CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP042489	Enterobacter hormaechei strain C15 plasmid pC15_001, complete sequence	0 crisprs	csa3	0	3
NZ_CP042491	Enterobacter hormaechei strain C15 plasmid pC15_003, complete sequence	0 crisprs	NA	0	0
NZ_CP042490	Enterobacter hormaechei strain C15 plasmid pC15_002	0 crisprs	DEDDh	0	0
NZ_CP042488	Enterobacter hormaechei strain C15 chromosome, complete genome	3 crisprs	WYL,csa3,DEDDh,RT,DinG,cas3	2	7
NZ_CP042492	Enterobacter hormaechei strain C15 plasmid pC15_004, complete sequence	0 crisprs	NA	0	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

70517 : 121462

Enterobacteria_phage(20.0%)

integrase,protease,transposase

attL 63348:63361|attR 128498:128511

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
63348:63361	attL	NA	NA	NA	NA
WP_001585166.1\|70517_71597_-\|protease	cysteine protease StiP family protein	A0A172Q0S8	Acinetobacter_phage	2.8e-38	34.1
WP_001040058.1\|71598_72372_-	hypothetical protein	NA	NA	NA	NA
WP_001280115.1\|72364_73507_-	hypothetical protein	A0A172Q0Y1	Acinetobacter_phage	6.5e-30	34.5
WP_012695441.1\|73516_74575_-	hypothetical protein	NA	NA	NA	NA
WP_000254137.1\|74895_75477_+	tellurium resistance-associated protein TerZ	K4JRX3	Caulobacter_phage	6.3e-13	30.0
WP_001054786.1\|75476_76634_+	tellurium resistance protein TerA	NA	NA	NA	NA
WP_000007449.1\|76656_77112_+	tellurite resistance TerB family protein	NA	NA	NA	NA
WP_000255079.1\|77134_78175_+	tellurium resistance membrane protein TerC	K7QKE8	Escherichia_phage	2.2e-77	48.0
WP_000116680.1\|78223_78802_+	tellurium resistance membrane protein TerD	A0A2P1N0L4	Streptomyces_phage	2.5e-06	40.0
WP_000301247.1\|78870_79446_+	tellurium resistance protein TerE	K4JRX3	Caulobacter_phage	8.7e-31	41.6
WP_001053340.1\|79874_81116_+	tellurium resistance protein TerF	NA	NA	NA	NA
WP_000374058.1\|81206_81662_+	hypothetical protein	NA	NA	NA	NA
WP_000398479.1\|81902_82094_-	hypothetical protein	NA	NA	NA	NA
WP_001151572.1\|82185_82527_-	hypothetical protein	NA	NA	NA	NA
WP_000880375.1\|83513_83768_+	hypothetical protein	NA	NA	NA	NA
WP_000166877.1\|83770_85810_-	ATP-dependent helicase	E3T5J8	Cafeteria_roenbergensis_virus	1.7e-25	25.3
WP_000211823.1\|85806_86793_-	hypothetical protein	NA	NA	NA	NA
WP_000341066.1\|87713_88106_+	hypothetical protein	NA	NA	NA	NA
WP_012695443.1\|88084_88396_+	hypothetical protein	NA	NA	NA	NA
WP_000462754.1\|88764_89421_+\|protease	trypsin-like serine protease	NA	NA	NA	NA
WP_123906519.1\|89460_89643_+	hypothetical protein	NA	NA	NA	NA
WP_000340139.1\|89623_90121_+	membrane protein	NA	NA	NA	NA
WP_012695445.1\|90125_91514_+	hypothetical protein	NA	NA	NA	NA
WP_012477377.1\|91914_92208_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000088044.1\|92212_93538_+	type II toxin-antitoxin system HipA family toxin	NA	NA	NA	NA
WP_000134171.1\|93598_93805_+	hypothetical protein	NA	NA	NA	NA
WP_000985909.1\|93905_94316_+	hypothetical protein	NA	NA	NA	NA
WP_001805097.1\|94328_94853_+	hypothetical protein	NA	NA	NA	NA
WP_050868990.1\|95034_96039_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_000405672.1\|96129_96564_-	Cd(II)/Pb(II)-responsive transcriptional regulator	NA	NA	NA	NA
WP_033488201.1\|96649_99055_+	heavy metal translocating P-type ATPase	E4ZFI9	Streptococcus_phage	3.9e-141	46.0
WP_000118563.1\|99051_100128_+	signal peptidase II	NA	NA	NA	NA
WP_000993245.1\|100136_100349_-	DUF3330 domain-containing protein	NA	NA	NA	NA
WP_001446012.1\|100311_100431_+	hypothetical protein	NA	NA	NA	NA
WP_001087807.1\|100414_100651_-	broad-spectrum mercury transporter MerE	NA	NA	NA	NA
WP_001277466.1\|100647_101013_-	mercury resistance co-regulator MerD	NA	NA	NA	NA
WP_000209296.1\|101030_102716_-	mercury(II) reductase	A0A2K5B2C5	Erysipelothrix_phage	1.8e-39	29.1
WP_000522996.1\|102754_103180_-	organomercurial transporter MerC	NA	NA	NA	NA
WP_000732275.1\|103207_103483_-	mercury resistance system periplasmic binding protein MerP	NA	NA	NA	NA
WP_001294656.1\|103498_103864_-	mercuric ion transporter MerT	NA	NA	NA	NA
WP_001166628.1\|103935_104391_+	Hg(II)-responsive transcriptional regulator	NA	NA	NA	NA
WP_000278471.1\|105068_105494_+	hypothetical protein	NA	NA	NA	NA
WP_001224686.1\|106042_106351_+	hypothetical protein	NA	NA	NA	NA
WP_000784387.1\|106366_107224_+	HNH endonuclease	G0X580	Salmonella_phage	3.9e-11	34.2
WP_001194554.1\|107285_107489_+	hypothetical protein	NA	NA	NA	NA
WP_001287391.1\|107830_108235_-	H-NS histone family protein	NA	NA	NA	NA
WP_001100635.1\|108412_108706_-	hypothetical protein	NA	NA	NA	NA
WP_000175475.1\|108731_108968_-	hypothetical protein	NA	NA	NA	NA
WP_000490638.1\|109522_110188_-	hypothetical protein	NA	NA	NA	NA
WP_001371925.1\|110245_110626_-	hypothetical protein	NA	NA	NA	NA
WP_000027057.1\|110955_111816_-	class A broad-spectrum beta-lactamase TEM-1	Q1MVP3	Enterobacteria_phage	4.6e-161	100.0
WP_001235713.1\|111998_112556_-	recombinase family protein	Q1MVP4	Enterobacteria_phage	7.0e-94	100.0
WP_001143760.1\|112719_115725_+\|transposase	Tn3-like element Tn3 family transposase	Q1MVP5	Enterobacteria_phage	0.0e+00	100.0
WP_001067855.1\|119516_120221_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_000174662.1\|120697_121462_-\|integrase	tyrosine-type recombinase/integrase	I3WFA4	Macacine_betaherpesvirus	1.9e-25	52.4
128498:128511	attR	NA	NA	NA	NA

DBSCAN-SWA_2

152293 : 184394

uncultured_Caudovirales_phage(46.15%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001067855.1\|152293_152998_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_001572372.1\|153163_153640_-	WbuC family cupin fold metalloprotein	NA	NA	NA	NA
WP_001572373.1\|153716_155336_-	phosphoethanolamine--lipid A transferase MCR-9.1	NA	NA	NA	NA
WP_001572374.1\|155524_156448_-\|transposase	IS5 family transposase	Q9MCT5	Escherichia_phage	2.4e-176	99.3
WP_004248839.1\|156531_157878_+	copper resistance membrane spanning protein PcoS	W8CYF6	Bacillus_phage	8.8e-18	26.6
WP_000723070.1\|158095_158530_+	hypothetical protein	NA	NA	NA	NA
WP_001572377.1\|158787_159903_-	nickel/cobalt efflux protein RcnA	NA	NA	NA	NA
WP_000019951.1\|160025_160298_+	Ni(II)/Co(II)-binding transcriptional repressor RcnR	NA	NA	NA	NA
WP_000193207.1\|160763_161582_+	DUF4942 domain-containing protein	NA	NA	NA	NA
WP_001371952.1\|161578_162784_+	hypothetical protein	NA	NA	NA	NA
WP_000121164.1\|162847_163051_-	hypothetical protein	NA	NA	NA	NA
WP_000078513.1\|163063_164383_-	DUF1173 family protein	NA	NA	NA	NA
WP_000833380.1\|164633_166061_-	DNA cytosine methyltransferase	E5E3X6	Burkholderia_phage	3.4e-100	52.3
WP_000464825.1\|166275_166791_+	thermonuclease family protein	A0A1X6WF84	Pacmanvirus	2.1e-07	38.6
WP_000975181.1\|166793_167690_+	hypothetical protein	NA	NA	NA	NA
WP_001005009.1\|167737_168052_+	hypothetical protein	NA	NA	NA	NA
WP_000637193.1\|168125_168383_+	hypothetical protein	NA	NA	NA	NA
WP_001371948.1\|168441_168675_+	hypothetical protein	NA	NA	NA	NA
WP_001046767.1\|168720_168975_+	hypothetical protein	NA	NA	NA	NA
WP_000443289.1\|169012_169300_+	hypothetical protein	NA	NA	NA	NA
WP_001371914.1\|169369_169567_+	hypothetical protein	NA	NA	NA	NA
WP_000864986.1\|169707_169983_+	hypothetical protein	NA	NA	NA	NA
WP_000927306.1\|170474_171953_+	SulP family inorganic anion transporter	A0A2H4J153	uncultured_Caudovirales_phage	7.3e-199	74.4
WP_001066652.1\|171971_172799_+	universal stress protein	A0A2H4J154	uncultured_Caudovirales_phage	4.9e-43	37.2
WP_000065802.1\|172858_173284_-	arsenate reductase (glutaredoxin)	A0A2H4J8T1	uncultured_Caudovirales_phage	1.6e-50	70.7
WP_000922628.1\|173296_174586_-	arsenic transporter	A0A2H4J144	uncultured_Caudovirales_phage	9.9e-168	71.4
WP_000941305.1\|174631_174952_-	transcriptional regulator	A0A2H4J145	uncultured_Caudovirales_phage	1.7e-20	53.7
WP_000130816.1\|175038_175743_+	arsenical resistance protein ArsH	A0A2H4J5V6	uncultured_Caudovirales_phage	8.8e-86	72.9
WP_000125668.1\|175775_177179_-\|transposase	ISNCY family transposase	NA	NA	NA	NA
WP_012695466.1\|177398_178322_-\|transposase	IS5-like element IS903B family transposase	Q1MVF0	Enterobacteria_phage	4.6e-175	98.7
WP_001567369.1\|178441_179074_+	hypothetical protein	NA	NA	NA	NA
WP_001567368.1\|179102_180506_-\|transposase	ISNCY-like element ISKpn21 family transposase	NA	NA	NA	NA
WP_000785965.1\|180719_181037_+	hypothetical protein	NA	NA	NA	NA
WP_001100610.1\|181059_181365_+	hypothetical protein	NA	NA	NA	NA
WP_000285959.1\|181409_182081_+	trypsin-like peptidase domain-containing protein	NA	NA	NA	NA
WP_001371904.1\|182538_182946_+	hypothetical protein	NA	NA	NA	NA
WP_000900745.1\|182996_183314_-	hypothetical protein	NA	NA	NA	NA
WP_122966916.1\|183282_183498_-	hypothetical protein	NA	NA	NA	NA
WP_100185530.1\|183479_184394_-\|transposase	IS5 family transposase	A0A077SK28	Escherichia_phage	3.6e-172	98.4

DBSCAN-SWA_3

227549 : 297444

Escherichia_phage(48.15%)

integrase,protease,transposase

attL 243426:243485|attR 299667:302706

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000219087.1\|227549_228788_-\|transposase	IS110 family transposase	A0A0U3ULR1	Bacillus_phage	2.5e-11	23.1
WP_000589001.1\|229209_230550_-\|transposase	ISNCY family transposase	NA	NA	NA	NA
WP_085949440.1\|230724_232094_-\|transposase	IS3-like element ISKpn8 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	9.4e-108	95.5
WP_000137794.1\|232426_233032_-	hypothetical protein	NA	NA	NA	NA
WP_000703842.1\|233248_233530_-	hypothetical protein	NA	NA	NA	NA
WP_000633161.1\|233905_234217_-	hypothetical protein	NA	NA	NA	NA
WP_000814953.1\|234439_234640_-	hypothetical protein	NA	NA	NA	NA
WP_000551490.1\|234679_234904_-	hypothetical protein	NA	NA	NA	NA
WP_000781547.1\|234958_235162_-	hypothetical protein	NA	NA	NA	NA
WP_024143014.1\|235341_235635_-	hypothetical protein	I7B2L9	Escherichia_phage	4.1e-05	38.6
WP_001371932.1\|235714_236206_-	DUF3085 domain-containing protein	NA	NA	NA	NA
WP_001165367.1\|236210_236522_-	DUF957 domain-containing protein	NA	NA	NA	NA
WP_000071366.1\|237038_237359_-	hypothetical protein	NA	NA	NA	NA
WP_001371935.1\|237537_237768_-	hypothetical protein	NA	NA	NA	NA
WP_000252081.1\|237939_238833_-	hypothetical protein	NA	NA	NA	NA
WP_001067855.1\|239142_239847_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_000842134.1\|240336_241446_-	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase	E3SJ82	Synechococcus_phage	2.8e-33	30.2
WP_001039466.1\|241540_242725_-	tetracycline efflux MFS transporter Tet(D)	NA	NA	NA	NA
WP_000113282.1\|242820_243477_+	TetR family transcriptional regulator	NA	NA	NA	NA
243426:243485	attL	NA	NA	NA	NA
WP_001067855.1\|243488_244193_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_001011939.1\|244336_244978_-	type A-2 chloramphenicol O-acetyltransferase CatII	G3CFL0	Escherichia_phage	7.3e-55	45.9
WP_001239317.1\|245127_245628_-	hypothetical protein	NA	NA	NA	NA
WP_001067855.1\|245707_246412_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_000057569.1\|246751_247093_+	hypothetical protein	NA	NA	NA	NA
WP_004248792.1\|247107_247899_-\|protease	zinc metalloprotease	NA	NA	NA	NA
WP_000480968.1\|248079_248916_-	aminoglycoside O-phosphotransferase APH(6)-Id	NA	NA	NA	NA
WP_001082319.1\|248915_249719_-	aminoglycoside O-phosphotransferase APH(3'')-Ib	NA	NA	NA	NA
WP_000845048.1\|249876_250890_+\|integrase	class 1 integron integrase IntI1	A0A1P8DJJ6	Virus_Rctr41k	1.0e-71	45.5
WP_072058701.1\|250858_251110_+\|transposase	transposase	NA	NA	NA	NA
WP_000019304.1\|251492_252062_-	trimethoprim-resistant dihydrofolate reductase DfrA19	A0A1V0SD48	Indivirus	3.5e-08	27.2
WP_002008781.1\|252061_252562_-	hypothetical protein	A0A1V0SB21	Catovirus	3.3e-10	31.7
WP_000050481.1\|252827_254369_-\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_000259031.1\|254773_255613_-	sulfonamide-resistant dihydropteroate synthase Sul1	A0A0B5J4J5	Pandoravirus	5.0e-11	27.2
WP_052238321.1\|255606_255942_-	ethidium bromide resistance protein	NA	NA	NA	NA
WP_025999322.1\|255834_256200_+	hydrogenase maturation nickel metallochaperone HypA	NA	NA	NA	NA
WP_004193231.1\|256203_257079_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_012579084.1\|257264_257921_-	quinolone resistance pentapeptide repeat protein QnrA1	NA	NA	NA	NA
WP_000050481.1\|258184_259726_-\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_000259031.1\|260130_260970_-	sulfonamide-resistant dihydropteroate synthase Sul1	A0A0B5J4J5	Pandoravirus	5.0e-11	27.2
WP_000679427.1\|260963_261311_-	quaternary ammonium compound efflux SMR transporter QacE delta 1	NA	NA	NA	NA
WP_001261740.1\|261474_262266_-	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA2	NA	NA	NA	NA
WP_000845048.1\|262411_263425_+\|integrase	class 1 integron integrase IntI1	A0A1P8DJJ6	Virus_Rctr41k	1.0e-71	45.5
WP_122997120.1\|263393_263669_+\|transposase	transposase	NA	NA	NA	NA
WP_001173919.1\|263767_264343_-	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	5.6e-46	52.7
WP_011191340.1\|264469_264718_-	type II toxin-antitoxin system YafQ family toxin	NA	NA	NA	NA
WP_001067834.1\|264976_265681_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	3.1e-139	99.6
WP_001138070.1\|265801_268768_+\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	0.0e+00	72.9
WP_000427619.1\|268846_269851_+\|transposase	IS110-like element IS5075 family transposase	NA	NA	NA	NA
WP_000027057.1\|270376_271237_-	class A broad-spectrum beta-lactamase TEM-1	Q1MVP3	Enterobacteria_phage	4.6e-161	100.0
WP_000971921.1\|272057_273428_-\|transposase	IS1182-like element ISCfr1 family transposase	NA	NA	NA	NA
WP_000080861.1\|273542_274679_-	DUF3883 domain-containing protein	NA	NA	NA	NA
WP_001330846.1\|274729_274975_-	hypothetical protein	NA	NA	NA	NA
WP_000951934.1\|274980_275172_+	hypothetical protein	NA	NA	NA	NA
WP_000587837.1\|275653_276196_-	AAA family ATPase	NA	NA	NA	NA
WP_000557454.1\|276208_277069_-	aminoglycoside N-acetyltransferase AAC(3)-IId	NA	NA	NA	NA
WP_001067855.1\|277301_278006_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_000219391.1\|278127_279033_+	Mph(A) family macrolide 2'-phosphotransferase	NA	NA	NA	NA
WP_000004159.1\|279029_280268_+	MFS transporter	NA	NA	NA	NA
WP_001137892.1\|280267_280852_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_001336397.1\|280797_281154_+	hypothetical protein	NA	NA	NA	NA
WP_001389365.1\|281344_282109_-\|transposase	IS6-like element IS6100 family transposase	A0A077SL39	Escherichia_phage	4.3e-86	65.7
WP_024143553.1\|282137_282320_+	hypothetical protein	NA	NA	NA	NA
WP_000130000.1\|282335_282641_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000184001.1\|282651_283857_-	chromate efflux transporter	NA	NA	NA	NA
WP_000427623.1\|284084_285089_+\|transposase	IS110-like element IS4321 family transposase	NA	NA	NA	NA
WP_004883563.1\|285270_285543_-	hypothetical protein	NA	NA	NA	NA
WP_001993321.1\|285561_285741_+	hypothetical protein	NA	NA	NA	NA
WP_000259031.1\|285670_286510_-	sulfonamide-resistant dihydropteroate synthase Sul1	A0A0B5J4J5	Pandoravirus	5.0e-11	27.2
WP_000679427.1\|286503_286851_-	quaternary ammonium compound efflux SMR transporter QacE delta 1	NA	NA	NA	NA
WP_001749986.1\|287073_287526_-	NAD(+)--rifampin ADP-ribosyltransferase Arr-3	NA	NA	NA	NA
WP_000186237.1\|287610_288243_-	type B-3 chloramphenicol O-acetyltransferase CatB3	A0A2R8FE91	Brazilian_cedratvirus	4.1e-26	41.2
WP_001334766.1\|288380_289211_-	oxacillin-hydrolyzing class D beta-lactamase OXA-1	NA	NA	NA	NA
WP_039052651.1\|289341_289941_-	AAC(6')-Ib family aminoglycoside 6'-N-acetyltransferase	NA	NA	NA	NA
WP_015344971.1\|290952_291237_+	hypothetical protein	NA	NA	NA	NA
WP_001067855.1\|291458_292163_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_071538079.1\|292153_292336_+	hypothetical protein	NA	NA	NA	NA
WP_002904004.1\|292299_293160_+	class A extended-spectrum beta-lactamase SHV-12	A0A077SL40	Escherichia_phage	2.2e-155	99.3
WP_002210513.1\|293180_293942_-	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	1.9e-134	100.0
WP_023148136.1\|293932_294166_+	hypothetical protein	NA	NA	NA	NA
WP_002903955.1\|294203_295106_+	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	2.6e-159	99.7
WP_001067855.1\|296739_297444_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
299667:302706	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP042488

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP042488_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042488_1

1283159-1283273

Orphan

Consensus_repeat	Method
GCCCTCACCCCAGCCCTCTCCCACAGGGAGAGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP042488_1

>merge|NZ_CP042488|1|1283159-1283273|CRISPRCasFinder
GCCCTCACCCCAGCCCTCTCCCACAGGGAGAGGGAGCAAACACTAAAAACGGCAACGGGGTTGCCGTTTTGCTTTTACCTCGCCCTCACCCCGGCCCTCTCCCACAGGGAGAGGG

>NZ_CP042488|1|1|1283159-1283273|CRISPRCasFinder
GCCCTCACCCCAGCCCTCTCCCACAGGGAGAGGG	AGCAAACACTAAAAACGGCAACGGGGTTGCCGTTTTGCTTTTACCTC
GCCCTCACCCCGGCCCTCTCCCACAGGGAGAGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042488.1\|WP_022650569.1\|1295203_1296163_-\|Fe2+-enterobactin-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|236806
NZ_CP042488.1\|WP_003858827.1\|1275717_1276305_-\|transcriptional-regulator-BetI	unknown	unknown	gnl\|CDD\|179115
NZ_CP042488.1\|WP_058691480.1\|1281663_1282503_+\|metal-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224033
NZ_CP042488.1\|WP_022650562.1\|1283290_1285531_-\|TonB-dependent-siderophore-receptor	unknown	unknown	gnl\|CDD\|237410
NZ_CP042488.1\|WP_032645860.1\|1285677_1286877_+\|enterochelin-esterase	unknown	unknown	gnl\|CDD\|236695
NZ_CP042488.1\|WP_003858806.1\|1286887_1287100_+\|MbtH-family-NRPS-accessory-protein	unknown	unknown	gnl\|CDD\|225790
NZ_CP042488.1\|WP_022650570.1\|1296351_1297527_+\|isochorismate-synthase-EntC	unknown	unknown	gnl\|CDD\|184977
NZ_CP042488.1\|WP_003858831.1\|1272553_1274218_-\|choline-dehydrogenase	unknown	unknown	gnl\|CDD\|235000
NZ_CP042488.1\|WP_022650558.1\|1279101_1280013_+\|iron/manganese-ABC-transporter-substrate-binding-protein-SitA	unknown	unknown	gnl\|CDD\|238557
NZ_CP042488.1\|WP_022650565.1\|1291010_1291811_-\|iron-enterobactin-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|182336
NZ_CP042488.1\|WP_151550372.1\|1276433_1278467_+\|choline-BCCT-transporter-BetT	unknown	unknown	gnl\|CDD\|236635
NZ_CP042488.1\|WP_022647369.1\|1280818_1281667_+\|iron/manganese-ABC-transporter-permease-subunit-SitC	unknown	unknown	gnl\|CDD\|334323
NZ_CP042488.1\|WP_022650559.1\|1280015_1280822_+\|iron/manganese-ABC-transporter-ATP-binding-protein-SitB	unknown	unknown	gnl\|CDD\|185016
NZ_CP042488.1\|WP_022650568.1\|1293909_1295157_+\|enterobactin-transporter-EntS	unknown	unknown	gnl\|CDD\|236700
NZ_CP042488.1\|WP_022650555.1\|1274231_1275704_-\|betaine-aldehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|183918
NZ_CP042488.1\|WP_022650564.1\|1287096_1290954_+\|enterobactin-non-ribosomal-peptide-synthetase-EntF	unknown	unknown	gnl\|CDD\|236668
NZ_CP042488.1\|WP_022650557.1\|1278605_1278890_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|225495
NZ_CP042488.1\|WP_022650561.1\|1282438_1283128_-\|enterobactin-synthase-subunit-EntD	unknown	unknown	gnl\|CDD\|182334
NZ_CP042488.1\|WP_072139725.1\|1291807_1292797_-\|iron-enterobactin-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|182463
NZ_CP042488.1\|WP_022650567.1\|1292796_1293801_-\|Fe(3+)-siderophore-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|182464

Protein	Function_ID	Function_description	E-value
NZ_CP042488.1\|WP_022650569.1\|1295203_1296163_-\|Fe2+-enterobactin-ABC-transporter-substrate-binding-protein	gnl\|CDD\|236806	PRK10957, PRK10957, iron-enterobactin transporter periplasmic binding protein; Provisional.	0
NZ_CP042488.1\|WP_003858827.1\|1275717_1276305_-\|transcriptional-regulator-BetI	gnl\|CDD\|179115	PRK00767, PRK00767, transcriptional regulator BetI; Validated.	3.33362e-117
NZ_CP042488.1\|WP_058691480.1\|1281663_1282503_+\|metal-ABC-transporter-permease	gnl\|CDD\|224033	COG1108, ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism].	3.2711e-72
NZ_CP042488.1\|WP_022650562.1\|1283290_1285531_-\|TonB-dependent-siderophore-receptor	gnl\|CDD\|237410	PRK13524, PRK13524, FepA family TonB-dependent siderophore receptor.	0
NZ_CP042488.1\|WP_032645860.1\|1285677_1286877_+\|enterochelin-esterase	gnl\|CDD\|236695	PRK10439, PRK10439, enterobactin/ferric enterobactin esterase; Provisional.	0
NZ_CP042488.1\|WP_003858806.1\|1286887_1287100_+\|MbtH-family-NRPS-accessory-protein	gnl\|CDD\|225790	COG3251, COG3251, Uncharacterized protein conserved in bacteria [Function unknown].	6.57585e-27
NZ_CP042488.1\|WP_022650570.1\|1296351_1297527_+\|isochorismate-synthase-EntC	gnl\|CDD\|184977	PRK15016, PRK15016, isochorismate synthase EntC; Provisional.	0
NZ_CP042488.1\|WP_003858831.1\|1272553_1274218_-\|choline-dehydrogenase	gnl\|CDD\|235000	PRK02106, PRK02106, choline dehydrogenase; Validated.	0
NZ_CP042488.1\|WP_022650558.1\|1279101_1280013_+\|iron/manganese-ABC-transporter-substrate-binding-protein-SitA	gnl\|CDD\|238557	cd01137, PsaA, Metal binding protein PsaA. These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species. They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains. In addition, these proteins sometimes have a low complexity region containing a metal-binding histidine-rich motif (repetitive HDH sequence).	9.21772e-151
NZ_CP042488.1\|WP_022650565.1\|1291010_1291811_-\|iron-enterobactin-ABC-transporter-ATP-binding-protein	gnl\|CDD\|182336	PRK10253, PRK10253, iron-enterobactin ABC transporter ATP-binding protein.	0
NZ_CP042488.1\|WP_151550372.1\|1276433_1278467_+\|choline-BCCT-transporter-BetT	gnl\|CDD\|236635	PRK09928, PRK09928, choline transport protein BetT; Provisional.	0
NZ_CP042488.1\|WP_022647369.1\|1280818_1281667_+\|iron/manganese-ABC-transporter-permease-subunit-SitC	gnl\|CDD\|334323	pfam00950, ABC-3, ABC 3 transport family.	6.83391e-81
NZ_CP042488.1\|WP_022650559.1\|1280015_1280822_+\|iron/manganese-ABC-transporter-ATP-binding-protein-SitB	gnl\|CDD\|185016	PRK15056, PRK15056, manganese/iron ABC transporter ATP-binding protein.	0
NZ_CP042488.1\|WP_022650568.1\|1293909_1295157_+\|enterobactin-transporter-EntS	gnl\|CDD\|236700	PRK10489, PRK10489, enterobactin transporter EntS.	0
NZ_CP042488.1\|WP_022650555.1\|1274231_1275704_-\|betaine-aldehyde-dehydrogenase	gnl\|CDD\|183918	PRK13252, PRK13252, betaine aldehyde dehydrogenase; Provisional.	0
NZ_CP042488.1\|WP_022650564.1\|1287096_1290954_+\|enterobactin-non-ribosomal-peptide-synthetase-EntF	gnl\|CDD\|236668	PRK10252, entF, enterobactin non-ribosomal peptide synthetase EntF.	0
NZ_CP042488.1\|WP_022650557.1\|1278605_1278890_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|225495	COG2944, COG2944, Predicted transcriptional regulator [Transcription].	4.42847e-14
NZ_CP042488.1\|WP_022650561.1\|1282438_1283128_-\|enterobactin-synthase-subunit-EntD	gnl\|CDD\|182334	PRK10251, PRK10251, enterobactin synthase subunit EntD.	6.17909e-70
NZ_CP042488.1\|WP_072139725.1\|1291807_1292797_-\|iron-enterobactin-ABC-transporter-permease	gnl\|CDD\|182463	PRK10440, PRK10440, iron-enterobactin ABC transporter permease.	0
NZ_CP042488.1\|WP_022650567.1\|1292796_1293801_-\|Fe(3+)-siderophore-ABC-transporter-permease	gnl\|CDD\|182464	PRK10441, PRK10441, Fe(3+)-siderophore ABC transporter permease.	3.57166e-175

>NZ_CP042488.1|WP_022650561.1|1282438_1283128_-|enterobactin-synthase-subunit-EntD
MHTTHSTFSLAGHTLHRITFDPTTFTDADLLWLPHHAQLANAGRKRKADHLAGRIAAAHALPDYTMPAIGPSGEPLWPQGISGSITHSGTQAIAVVTQYPALIGIDCETILSENEAREIKDGIIDTQEEPVLFRLGYPFALALTLVFSAKESLFKALFPQVQAWMGFDCARVTMLDDKTLTLALTCQLADFQEGTAFPLHWQQHGEQVITLLSHAPGDEPSRWSPQTSR
>NZ_CP042488.1|WP_058691480.1|1281663_1282503_+|metal-ABC-transporter-permease
MMTLLLEPFQFAFMNNALLISLLVAVPCALLSVFLVLKGWALMGDAMSHAVFPGVVLAWMMGLPLALGAFVAGLFCAVATGYLKDNSRIKQDTVMGIVFSGMFGAGLILYIAVKPEVHLDHILFGDMLGINVMDILQSGLVAGLIALVIGLKWRDFLLFCFDYQQAQASGLRTRWLHYGLLCMVSLTIVATLKAVGIILSISLLIAPGAVAVLITRRFHMALLVAVAVSVLVSVSGVYASFYLDSAPAPTIVVLFAMVFIVTFVVTSVKARRQERVTAE
>NZ_CP042488.1|WP_022647369.1|1280818_1281667_+|iron/manganese-ABC-transporter-permease-subunit-SitC
MNALLEPFGYEYMLNAMWVSAMVGGLCAFLSCYLMLKGWSLIGDALSHSIVPGVAGAYMLGLPFSLGAFLSGGLAAGSMLFLNQRSRLKEDAIIGLIFSSFFGLGLFMVSLNPTSVNIQTIVLGNILAIAPEDIVQLAIIGVVSIVILLFKWKDLMVTFFDENHARAIGLRPERLKILFFTLLAVSTVAALQTVGAFLVICLVVTPGATAWLLTDRFPRLLMIAVAIGSITSFLGAWASYYLDGATGGIIVVAQTLLFLLAFVFAPKHGLLASRRRAREAHP
>NZ_CP042488.1|WP_022650559.1|1280015_1280822_+|iron/manganese-ABC-transporter-ATP-binding-protein-SitB
MQKGIVVTDVTVTYRNGHTALRDASFSVPGGSIAALVGVNGSGKSTLFKAVMGFVRAASGTISILGLPPHRALRQNLVAYVPQSEEVDWSFPVLVEDVVMMGRYGHMGFLRRPKECDKQIVTDALKRVDMLELRHRQIGELSGGQKKRVFLARAIAQQGEVILLDEPFTGVDVKTEARIISLLRELRDEGKTMLVSTHNLGSVTEFCDYTVMVKGTVLASGPTDITFTAENLERAFSGVLRHVVLSGSEDRIITDDERPFVAHRQEAK
>NZ_CP042488.1|WP_022650558.1|1279101_1280013_+|iron/manganese-ABC-transporter-substrate-binding-protein-SitA
MHPRQGLKRLLLGALLMTATTTGALAAEKFQVITTFTVIADMAKNVAGDAAEVTSITKPGAEIHEYQPTPGDIKRAQKAQLILANGMNLELWFQRFYQHLNGVPEVVVTKGITPMGISEGPYNGKPNPHAWMSPDNALIYVDNIRDALVKYDPANAQIYQRNADAYKQKITATLEPLRKQVAEIPEDKRWMVTSEGAFSYLARDLGLKELYLWPINADQQGTPQQVRKVIDLVKKHHIPAVFSESTVSDKPARQVARETGAHYGGVLYVDSLSAENGPVPTYIDLLNVTTRTLVQGIRDGMKE
>NZ_CP042488.1|WP_022650557.1|1278605_1278890_+|helix-turn-helix-domain-containing-protein
MSIFDELKTSLEEAVEIHSGRKAASRVTRYEVADVRAIREQLNITQSEMAKALGTSVDTIKSWESKRRNPTGLAAKVLNVIRENPAFYKALAGQ
>NZ_CP042488.1|WP_151550372.1|1276433_1278467_+|choline-BCCT-transporter-BetT
MTDLSQDREKDKINPVVFYTSAGLILLFSLTTIFFRDFSAEWIGRTLDWVSKTFGWYYLLAATLYIVFVVCIACSRFGSVKLGPEQSKPEFSLLSWAAMLFAAGIGIDLMFFSVAEPVTQYMQPPEGAGQTMEAARQAMVWTLFHYGLTGWSMYALMGMALGYFSYRYNLPLTIRSALYPIFGKKINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPDSMAAKAALIALSVIIATISVTSGVDKGIRVLFELNVALALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRPTEWMNNWTLFFWAWWVAWSPFVGLFLARISRGRTIRQFVMGTLIIPFTFTLLWLSIFGNSALHEIIHGNATFAQEAMAHPERGFYSLLAQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSKLKDINSDAPNWLRIFWSVAIGLLTLGMLMTNGISALQNTTVIMGLPFSFVIFFVMAGLYKSLKVEDYRRVSASRDTAPRPLGAQDRLSWKKRLSRLMNYPGTRYTKQMMETVCFPAMEEVAQELKLRGAYVELKNLPPEEGENLGHLDLLVHMGDEQNFVYQIWPQQYSVPGFTYRARSGKSTYYRLETFLLEGSQGNDLMDYSKEQVITDILDQYERHLNFIHLHREAPGNSVMFPDA
>NZ_CP042488.1|WP_003858827.1|1275717_1276305_-|transcriptional-regulator-BetI
MPKVGMQPIRRRQLIDATLEAINEVGMHDATIAQIARRAGVSTGIISHYFKDKNGLLEATMRDITGQLRDAVLSRLRALPDGSAEQRLQAIVGGNFDETQVSGAAMKAWLAFWASSMHQPMLYRLQQVSSRRLLSNLVYEFRRELPREQAEEAGYGLAALIDGLWLRAALSGKPLDKTLAQSLTSHFISQHLPTD
>NZ_CP042488.1|WP_022650555.1|1274231_1275704_-|betaine-aldehyde-dehydrogenase
MSRMAEQQLYINGGYTSATSGRTFETINPANGEVLATVQAAGREDVDRAVESAKRGQKIWAAMTAMERSRILRRAVDILRERNDELATLETLDTGKAYSETSTVDIVTGADVLEYYAGLIPALEGSQIPLRDTSFVYTRREPLGVVAGIGAWNYPIQIALWKSAPALAAGNAMIFKPSEVTPLTALKLAEIYTEAGLPDGVFNVLPGVGAETGQYLTEHPGIAKVSFTGGVASGKKVMANSAASSLKEVTMELGGKSPLIVFDDADLDLAADIAMMANFFSSGQVCTNGTRVFVPAKFKAAFEQKIVERVGRIRAGDLFDEATNFGPMVSFPHRDSVMRYIAKGKEEGARVLCGGDVLKGEGFDNGAWVAPTVFTDCTDEMTIVREEIFGPVMSILTYESIEEAIRRANDTDYGLAAGIVTTDLNRAHGAIHQLEAGICWINTWGESAAEMPVGGYKHSGIGRENGVMTLQSYTQVKSIQVEMGKFQSIF
>NZ_CP042488.1|WP_003858831.1|1272553_1274218_-|choline-dehydrogenase
MQFDYIIIGAGSAGNVLATRLTEDPNTTVLLLEAGGPDYRFDFRTQMPAALAFPLQGKRYNWAYETEPEPYMNNRRMECGRGKGLGGSSLINGMCYVRGNAMDLDNWAKEPGLEHWSYLNCLPYYRKAETRDVGPNDYHGGDGPVSVTTSKPGVNPLFEAMVEAGVQAGYPRTDDLNGYQQEGFGPMDRTVTPQGRRASTARGYLDQAKPRPNLTIRTHAMTDHIIFDGKRAVGVEWLEGESTIPSKATAKKEVLLCAGAIASPQILQRSGVGNAELLKQFDIPLVHDLPGVGENLQDHLEMYLQYECKEPVSLYPALQWWNQPKIGAEWLFGGTGVGASNHFEAGGFIRSREEFEWPNIQYHFLPVAINYNGSNAVKEHGFQCHVGSMRSPSRGHVRIKSRDPHQHPAILFNYMSHEQDWQEFRDAIRITREIMHQPALDKYRGREISPGVECQTDEQLDEFVRNHAETAFHPCGTCKMGYDEMAVVDGEGRVHGLEGLRVVDASIMPQIITGNLNATTIMIGEKIADAIRGREPLAKSTAAYYVANGAPVRR
>NZ_CP042488.1|WP_022650562.1|1283290_1285531_-|TonB-dependent-siderophore-receptor
MNKKIHSLALLVNLGIYGVALPAMADDNTASAQNEDTMVITAAEQNLQAPGVSTITADEIRKNPPARDVAEIIRTMPGVNLTGNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVTSRNSIRLGWRGERDTRGDTGWVPPEMIERIEVIRGPAAARYGNGAAGGVVNIITKKFDDQWHGSWNTYLNAPEHKDEGSTKRTNFSLSGPLGGDFSFRMYGNLDKTQADAWDINQGHQSDRTGAYANTLPAGREGVENKDINGVVRWDFAPMQSLEFEAGYSRQNNLYAGDTQNTNNDNALVKKNYGKETNRIYRQNFAVTWNGGWDNGITTSNWAQYEHTRNSRLGEGLAGGLEGLFNSNKFTDTDLADVMLHSEINLPIDFIVNQNLTLGTEWNQQRMKDSTSFTQTQQGGTIPGMSEDRSPYTSAEIFSLFAENNMELTDSTMLTPALRFDHHTIVGNNWSPSLNLSQGLGDDFTLKMGIARAYKAPSLYQTNPNYLLYSKGQGCYASSDGVGCYMMGNDDLKAETSINKEIGLEWKRDGWLAGVTWFRNDYRNKIEAGYAPIGQTSTGKVTTDIYQWENVPKAVVEGLEGSLNVPVSDTINWTNNITYMLQSKNKETGDRLSIIPEYTLNSTLSWQVRQDVSLQSTFTWYGKQQPKKYNYKGQPVTGSEKDEVSPYSIVGLSATWDVTKNVSLTGGVDNVFDKRQWRAGNAQTTGNTTTGAYMYGAGAYTYNEPGRTWYMSVNTRF
>NZ_CP042488.1|WP_032645860.1|1285677_1286877_+|enterochelin-esterase
MTALTTGSEAWWQTKNGPERERHQENYRVTFWWRDPAGTQKTSTVKRVWLYVTGVTDHHQNARPQSLERIPDTDVWQWQGEFSPEWRGSYCFIPSDNENDFADAVFEGEQPDRMALREGWRKLLPHAVSDPLNPQSWRGGRGHAVSALEMPEAPVQPGWNHPDTPYNKPVCIDWHSARLKNRRRVWIFTTGDESPERPLAVLLDGQFWAESMPVWPALASLTHEGKLPPAVYVLIDVIDTAHRSRELPCNPDFWLAVQEELLPQVKSMAPFSDRADHTVVAGQSFGGLSSLYAGLNWPQRFGCILSQSGSYWWPHRGAQQDGLLIEQLKAGEKTARGLRIVLEAGRNEPLILRANQAIFAELHTQQPVFWRQVDGGHDALCWRGGLTQGLMTLWQPLIQ
>NZ_CP042488.1|WP_003858806.1|1286887_1287100_+|MbtH-family-NRPS-accessory-protein
MEFSNPFDNPQGQFAILQNDQGQYSLWPQQCELPAGWRVVCEPQSQEACQQWLAEQWQTLEPFYFAGERA
>NZ_CP042488.1|WP_022650564.1|1287096_1290954_+|enterobactin-non-ribosomal-peptide-synthetase-EntF
MNRLPLVAAQPGIWMAEQLSSLPNAWSAAHYTELKGAIDAPLLAKAIAEGMMQADTLRMRFAEDHGEVWQWIDEAMLLPEPSIVRVDSHDAAVALMEADLKQNLRVDSGQPLAFHQLIQVGESHWYWYQRYHHLVVDGFSFPAITRQIAAIYAAWQKGEPAPASPFTPFAEVVEEYQRYRDSEAYQRDGAFWAEQRQQLPSPVSLSSAPLPGHAATTDILRLKMAMDGRAFSQLAQMAGQAQRTDLALALVVLWLGRLTGRLDYAAGFIFMRRMGSAALTATGPVLNVLPLAVNIRPHESLPELALRLANQLKKMRRHQRYDAEQIVRNSGRAAGDEALFGPVLNVKVFDYQLDIDGVEAITHTLATGPVNDLELALFPDEQGGLSIEILANGQRYDEATLKGHAARLNAMLTQFAANPDLRCGDVDTVSEQEYARLARINDTGLALPSTTLADLVAEQASKTPDAPALADAHTELNYRQMREQVVALANLLRARGVKPGDSVAVALPRSVFLTLALHGIVEAGAAWLPLDTGYPDDRLRMMLEDAKPSLLITTDEQLPRFSDLSVETFSYNTLLPTSGAEPLRLAKPEQTAYIIFTSGSTGRPKGVMVGHTAIVNRLKWMQDHYPLTAHDVVAQKTPCSFDVSVWEFWWPFIAGAKLVMAEPDAHRDPQAMQSFFAEYGVTTTHFVPSMLAAFVASLTPENAHCCRTLKQVFCSGEALPTALCREWEQLTHAPLHNLYGPTEAAVDVSWYPAYGPELAAVEGNSVPIGFPVWNTGLRILDAMMRPVPFGVAGDLYLTGIQLAQGYLGRPDLTASRFIADPFAPGERMYRTGDVARWLDNGAVEYLGRSDDQLKIRGQRIELGEIDRAMLSLPDVAQAVAHACVFNQAAATGGDARQLVGYVVSESGLPLDRDALLASLKAQLPPHMVPVVLLQISALPLSANGKLDRKALPLPELTSRTSGRAPETQTEVAVAQAFSSLLGCAVNDIEADFFALGGHSLLAMRLAAQLSRAFSRKVTPGQIMVASTVSKLSALLDSQMSDEQAQRLGYETLLPLRESNGPTLFCFHPASGFAWQFSVLARYLSPRWSIVGIQSPRPNGPMQQCADLDGVIEHHLNTLRKQQPQGPYYLFGYSLGGTLAQGIAARLREQGEAVAFLGLLDTWPPETQNWAEKEANGLDPAVLAEIERERQAFIAAQQGQGSSELFNAIEGNYADAVRLLTTAHSARFDGKATLFVAERTRTQDPQAAWAPWVGELEVYSQDCAHVDIISPQAFEKIGPVLKEILG
>NZ_CP042488.1|WP_022650565.1|1291010_1291811_-|iron-enterobactin-ABC-transporter-ATP-binding-protein
MTDLTTRLRGENLTLGYGKKIIARDLSVAIPDGHFTAIIGPNGCGKSTLLRTLSRLMSPVEGSVFLDGEQIQRFASKEVARRIGLLAQNATTPGDITVQELVSRGRYPHQPLFTRWRKEDDEAVKRAMQATGITELAQQSVDTLSGGQRQRAWIAMVLAQETSIMLLDEPTTWLDISHQIDLLELLSELNRTQGYTLAAVLHDLNQACRYATHLIALRDGEIVAQGAPKEIVTPELIARIYGMRCMIIDDPVAGTPLVVPLGKRAV
>NZ_CP042488.1|WP_072139725.1|1291807_1292797_-|iron-enterobactin-ABC-transporter-permease
MAPSRRLLTSVALLVVACLLLAVWSLQSGAVTLDFAQVFHALTGSAPRNITMVVTEWRLPRVAMAILVGAALGVSGAIFQSLMRNPLGSPDVMGLNTGAWSGVLVAMVLFGQHLTAITFTAMAGGILTSLLIWALAWRNGIDTFRLIIIGIGIRAMLMAFNTWLLLQASLETALSAGLWYAGSLNGLTWVKTWPAAPLIILMFIGALLLVRRMRLLEMGDDSACALGVSVERSRLMLMLVAVLLTAASTAIAGPISFIALVAPHIARRLSGTARWGLTQAALCGAVLLLAADLCAQRLFTPYQLPVGVVTVSLGGIYLIVLLVQESRKK
>NZ_CP042488.1|WP_022650567.1|1292796_1293801_-|Fe(3+)-siderophore-ABC-transporter-permease
MSFSSSAVRALAVPVLLLLLILAIALSLLVGAKPLPASVIVDALSGTCQSADCTIVLDARLPRTLAGLLAGGALGLAGALMQTLTRNPLADPGILGVNSGASFAIVLGAALFGFTSPSEQLVMAFCGALAASLVVAFTGSQGGGQLSPVRLTLAGVALAAVLEGLSNGIALLNPDVYDQLRFWQAGSLDIRTLETLKVVVIPASVAAAVALCLSRALNSLSLGSDTATALGNRVARTQLTGLLAITVLCGSATAVVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLLFADVLGRLLVPGELRVSVVSAFIGAPVLIFLVRRRRGGGA
>NZ_CP042488.1|WP_022650568.1|1293909_1295157_+|enterobactin-transporter-EntS
MNQKSWLLNLSLLKTHPAYRAVFIARFISILSLGLLGVAVPVQIQTITHSSWLVGLSVTLTGGAMFIGLMVGGVLADRYERKKLILLARGTCGVGFVGLCLNAMLPEPSLVAIYVLGLWDGFFASLGVTALLAATPALVGRENLMQAGAITMLTVRLGSVISPMVGGLLLATGNVAWNYGLAAAGTFITTLTLLRLPLLPPPPQPREHPLKSLMAAIRFLFSNPLIGGIALLGGLLTMASAVRVLYPALAGEWQMSASEIGVLYAAIPLGAACGALTSGNLAQSARPGLIMLVATLASFIAIGFFSLMPVWALGVMCLVIFGWLSAVSSLLQYTLIQTQTPEGMLGRINGLWTAQNVTGDAIGAAILGGMGAIMTPVASASSSGFVLAMIGAILLVTLVELRRFRQEVALNDGAA
>NZ_CP042488.1|WP_022650569.1|1295203_1296163_-|Fe2+-enterobactin-ABC-transporter-substrate-binding-protein
MKIAAVCRNALLLTGLFVLGLTSAAADDWPRQVSDSRGVHTLESKPTRIVSTSVTLTGSLLAIDAPVIASGATTPNNRVADAQGFLRQWGDIAKQRKVARLYIGEPSAEAVAAQMPDLILISATGGDSALALYDQLSAIAPTLIINYDDKSWQELLTQLGTITGQERQAAERIAAFDKQLAQVKQQMKLPPQPVNAIVYTAAAHTANLWTTDSAQGKLLHQLGFTLADLPAGLQTSTSQGKRHDIIQLGGENLATGLNGEGLFVFAGDQKDVNAIYANPLLAHLPSVKNKRVWALGTETFRLDYYSAMLVLDRLNALFK
>NZ_CP042488.1|WP_022650570.1|1296351_1297527_+|isochorismate-synthase-EntC
MDTSLAEEVQHTATTLQADSFFFMSPYRSFTTSGCFARFSEPAVGGDDPAGPFQQKLAQAFRNAKNSGIAHPVMVGAIPFDTRKPSSLFIPQRWQTFSRPARQQSARYASGAQTLNVQQRSEIPPQPVFEEMVARAASLTATPQVNKVVLSRLIDIATDKQIDSSALMERLIAQNPASFNFHVPLEDGGVLLGASPELLLRKEGAHFSSLPLAGSARRQPDDVLDREAGTKLLASEKDRHEHDLVTQAMKTILEPRSHHLSMPASPQLITTPTLWHLATPVEGDARENENALTLACLLHPTPALSGFPHQAAKELIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCARLHQNTVRLFAGAGIVPASSPVGEWRETGVKLSTMLNVFGLH

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Crispr_ID: NZ_CP042488_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042488_2

1989651-1989774

Orphan

Consensus_repeat	Method
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP042488_2

>merge|NZ_CP042488|2|1989651-1989774|CRISPRCasFinder
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTACAGACGCAAGATGGTGCGTTCAATTGGACTCGAACCAACGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA

>NZ_CP042488|2|2|1989651-1989774|CRISPRCasFinder
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	CAGACGCAAGATGGTGCGTTCAATTGGACTCGAACCAA
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042488.1\|WP_022650940.1\|1999376_2000135_-\|NlpC/P60-family-protein	unknown	unknown	gnl\|CDD\|366353
NZ_CP042488.1\|WP_058691407.1\|1994965_1995877_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182948
NZ_CP042488.1\|WP_003857648.1\|1988559_1988802_+\|cell-surface-composition-regulator-GlgS	unknown	unknown	gnl\|CDD\|179501
NZ_CP042488.1\|WP_022650932.1\|1980815_1982222_+\|DUF1996-domain-containing-protein	unknown	unknown	gnl\|CDD\|370451
NZ_CP042488.1\|WP_058691408.1\|1989934_1991308_-\|MdtK-family-multidrug-efflux-MATE-transporter	unknown	unknown	gnl\|CDD\|234981
NZ_CP042488.1\|WP_003857665.1\|1982278_1982419_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042488.1\|WP_003857629.1\|1998672_1999254_-\|superoxide-dismutase-[Fe]	unknown	unknown	gnl\|CDD\|182534
NZ_CP042488.1\|WP_003857639.1\|1993653_1994853_-\|Bcr/CflA-family-multidrug-efflux-MFS-transporter	unknown	unknown	gnl\|CDD\|182924
NZ_CP042488.1\|WP_022650939.1\|1997468_1998635_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|225371
NZ_CP042488.1\|WP_003857643.1\|1991533_1992175_+\|riboflavin-synthase	unknown	unknown	gnl\|CDD\|183846
NZ_CP042488.1\|WP_003857632.1\|1997217_1997307_+\|YnhF-family-membrane-protein	unknown	unknown	unknown
NZ_CP042488.1\|WP_003857641.1\|1992206_1993355_-\|cyclopropane-fatty-acyl-phospholipid-synthase	unknown	unknown	gnl\|CDD\|183282
NZ_CP042488.1\|WP_003857662.1\|1983399_1984035_+\|carbonic-anhydrase	unknown	unknown	gnl\|CDD\|238449
NZ_CP042488.1\|WP_022650934.1\|1986544_1987075_+\|type-VI-secretion-system-lipoprotein-TssJ	unknown	unknown	gnl\|CDD\|378947
NZ_CP042488.1\|WP_003857659.1\|1984063_1985659_-\|FAD-NAD(P)-binding-protein	unknown	unknown	gnl\|CDD\|182134
NZ_CP042488.1\|WP_003857634.1\|1995894_1996920_-\|HTH-type-transcriptional-repressor-PurR	unknown	unknown	gnl\|CDD\|236739
NZ_CP042488.1\|WP_003857647.1\|1988974_1989445_+\|Hsp20-family-protein	unknown	unknown	gnl\|CDD\|107227
NZ_CP042488.1\|WP_022650933.1\|1982544_1983327_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293813
NZ_CP042488.1\|WP_003857652.1\|1987074_1987518_+\|type-VI-secretion-system-baseplate-subunit-TssE	unknown	unknown	gnl\|CDD\|274540
NZ_CP042488.1\|WP_032610209.1\|1987849_1988245_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182205

Protein	Function_ID	Function_description	E-value
NZ_CP042488.1\|WP_058691407.1\|1994965_1995877_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|182948	PRK11074, PRK11074, putative DNA-binding transcriptional regulator; Provisional.	0
NZ_CP042488.1\|WP_003857648.1\|1988559_1988802_+\|cell-surface-composition-regulator-GlgS	gnl\|CDD\|179501	PRK02922, PRK02922, cell surface composition regulator GlgS.	1.33233e-28
NZ_CP042488.1\|WP_003857659.1\|1984063_1985659_-\|FAD-NAD(P)-binding-protein	gnl\|CDD\|182134	PRK09897, PRK09897, FAD-NAD(P)-binding protein.	0
NZ_CP042488.1\|WP_022650932.1\|1980815_1982222_+\|DUF1996-domain-containing-protein	gnl\|CDD\|370451	pfam09362, DUF1996, Domain of unknown function (DUF1996). This family of proteins are functionally uncharacterized.	3.09012e-31
NZ_CP042488.1\|WP_003857639.1\|1993653_1994853_-\|Bcr/CflA-family-multidrug-efflux-MFS-transporter	gnl\|CDD\|182924	PRK11043, PRK11043, Bcr/CflA family multidrug efflux MFS transporter.	0
NZ_CP042488.1\|WP_003857629.1\|1998672_1999254_-\|superoxide-dismutase-[Fe]	gnl\|CDD\|182534	PRK10543, PRK10543, superoxide dismutase [Fe].	1.40399e-136
NZ_CP042488.1\|WP_022650939.1\|1997468_1998635_+\|MFS-transporter	gnl\|CDD\|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	2.13866e-99
NZ_CP042488.1\|WP_003857662.1\|1983399_1984035_+\|carbonic-anhydrase	gnl\|CDD\|238449	cd00884, beta_CA_cladeB, Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.	1.47181e-91
NZ_CP042488.1\|WP_022650940.1\|1999376_2000135_-\|NlpC/P60-family-protein	gnl\|CDD\|366353	pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.	1.9126e-42
NZ_CP042488.1\|WP_003857641.1\|1992206_1993355_-\|cyclopropane-fatty-acyl-phospholipid-synthase	gnl\|CDD\|183282	PRK11705, PRK11705, cyclopropane fatty acyl phospholipid synthase.	0
NZ_CP042488.1\|WP_003857643.1\|1991533_1992175_+\|riboflavin-synthase	gnl\|CDD\|183846	PRK13020, PRK13020, riboflavin synthase subunit alpha; Provisional.	5.19053e-120
NZ_CP042488.1\|WP_022650934.1\|1986544_1987075_+\|type-VI-secretion-system-lipoprotein-TssJ	gnl\|CDD\|378947	pfam12790, T6SS-SciN, Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113. One of the virulence mechanisms of E coli is the production of toxins which it produces from dedicated machineries called secretion systems. Seven secretion systems have been described, which assemble from 3 to up to more than 20 subunits. These secretion systems derive from or have co-evolved with bacterial organelles such as ABC transporters (type I), type IV pili (type 2), flagella (type 3), or conjugative machines (type IV). The type VI secretion system (T6SS) is present in most pathogens that have contact with animals, plants, or humans. SciN is a lipoprotein tethered to the outer membrane and expressed in the periplasm of E coli and is essential for T6S-dependent secretion of the Hcp-like SciD protein and for biofilm formation.	1.04658e-38
NZ_CP042488.1\|WP_003857634.1\|1995894_1996920_-\|HTH-type-transcriptional-repressor-PurR	gnl\|CDD\|236739	PRK10703, PRK10703, HTH-type transcriptional repressor PurR.	0
NZ_CP042488.1\|WP_003857647.1\|1988974_1989445_+\|Hsp20-family-protein	gnl\|CDD\|107227	cd06470, ACD_IbpA-B_like, Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins. IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation and protect against cell stress, and are generally active as large oligomers consisting of multiple subunits. IbpA and IbpB are produced during high-level production of various heterologous proteins, specifically human prorenin, renin and bovine insulin-like growth factor 2 (bIGF-2), and are strongly associated with inclusion bodies containing these heterologous proteins. IbpA and IbpB work as an integrated system to stabilize thermally aggregated proteins in a disaggregation competent state. The chaperone activity of IbpB is also significantly elevated as the temperature increases from normal to heat shock. The high temperature results in the disassociation of 2-3-MDa IbpB oligomers into smaller approximately 600-kDa structures. This elevated activity seen under heat shock conditions is retained for an extended period of time after the temperature is returned to normal. IbpA also forms multimers.	3.67422e-40
NZ_CP042488.1\|WP_022650933.1\|1982544_1983327_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293813	cd07727, YmaE-like_MBL-fold, uncharacterized subgroup which includes Bacillus subtilis YmaE and related proteins; MBL-fold metallo hydrolase domain. Includes the uncharacterized Bacillus subtilis YmaE and Nostoc all1228 proteins.Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) from which this fold was named are only a small fraction of the activities which are included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry. .	1.00513e-54
NZ_CP042488.1\|WP_003857652.1\|1987074_1987518_+\|type-VI-secretion-system-baseplate-subunit-TssE	gnl\|CDD\|274540	TIGR03357, hypothetical_protein_Atu4338, type VI secretion system lysozyme-like protein. The description for Pfam family pfam04965 cites acidic lysozyme activity for some phage-encoded members. This family represents a different subgroup of the proteins from pfam04965, where all members are associated with bacterial type VI secretion system genomic contexts.	1.57425e-27
NZ_CP042488.1\|WP_058691408.1\|1989934_1991308_-\|MdtK-family-multidrug-efflux-MATE-transporter	gnl\|CDD\|234981	PRK01766, PRK01766, multidrug efflux protein; Reviewed.	0
NZ_CP042488.1\|WP_032610209.1\|1987849_1988245_+\|hypothetical-protein	gnl\|CDD\|182205	PRK10040, PRK10040, hypothetical protein; Provisional.	2.49139e-16

>NZ_CP042488.1|WP_003857647.1|1988974_1989445_+|Hsp20-family-protein
MMTLRTFPVLNDLSDSLFADRFNRIDRLFSQLTGSTPLPSTPSYNIRRLGDNRYELTLSVPGWKESELEIETVGGQLNISGKREEEKTENGEEGWIHRGISRSDFRASYSLPEHVKVTGASLENGLLAIELHQDIPEEEKPQRIAINNNPAIEHKP
>NZ_CP042488.1|WP_003857648.1|1988559_1988802_+|cell-surface-composition-regulator-GlgS
MTLNSNRSDWRDMLMKRQDINALKNFDFLARSFARMYALGQPVDIDAVTGNMSNKQQAWFRERYDHYRKQAERARVIELR
>NZ_CP042488.1|WP_032610209.1|1987849_1988245_+|hypothetical-protein
MKMRILLLMVSVLFNMQADAARGRQPCSGSKGGIAHCTSDGRFVCNDGSLSQSKRFCSGYGASELPRQVKPSPSARKAQTKKRIAVKGQEQRVVENNAQFDTQPRQPTCAPLYMANKPGFTHLPICSGNQY
>NZ_CP042488.1|WP_003857652.1|1987074_1987518_+|type-VI-secretion-system-baseplate-subunit-TssE
MPRPSLYDMLYGNFAGGLDLHSVSEENQLILSVLDNMQRILNCRAGTLAHLPDYGLPDMTKILQGMPGTAHQLITTLSAVLLKYEPRLSRINVVMQEQIQPGELRYAIDAELKGVGLVRYGTEFMPEGRVLIRHLKQQQYLDNTARL
>NZ_CP042488.1|WP_022650934.1|1986544_1987075_+|type-VI-secretion-system-lipoprotein-TssJ
MKMAITAGKALAITLATLLTGCGLTQKVTDGTVAVTKSIFYRQVKTLHLDIQAREGVNNNAKGASLATVVRIYQLKERKAFDSTDYPSLFASDTQAIKADLVAEKDIRLRPGESVTLDMPMEESAQVVAVAGMFMAPDQVNDTWRITLTRDGLDPDKARVIEVSNNRLTLKPLEGE
>NZ_CP042488.1|WP_003857659.1|1984063_1985659_-|FAD-NAD(P)-binding-protein
MKKIAIIGSGPTGIYTFYSLLNNAAPLSITVFEKADQPGVGMPYSDEDNSRLMLANIASIEIPPIFITYLDWLKQQNAARLARYNVDSEKLHDRQFLPRILLGEYFHDRFLAVAAEAKKAGFHIEVHPNAEVTDIKADADGVALSVNDAPFSRRFDLAVVATGHVWPDENETTRAYFPSPWSGLMDAEVRACEVGIMGTSLSGLDAAMAVVMQHGRFSGKQFVVNKGSEGLKIMLMSRTGVLPEADFYCPIPYEPLSVLTDCVVESEIDKGPDGLLDRIFALMVKELELADPRWCQAIALGTLNADTLRDAWFEDRKKHGPFTWAEANLKEVERNKREKRTVAWRYTVLRLHEVVQAIVPSLNEHDRERFKSGLERVFIDNYAAIPPQSIRRLLALREAGIISVVALGDDYDLDIGSDQTVITTAKKSYRFDVFIDARGQKPLRNKDIPFPTLRKQLAGTGDDVPDVGEDYTLLAPASLRGRIAFGAIPWLMHDHPFVQGLSECAEIGKAMAKAAGKPASGVRRKLPYMEF
>NZ_CP042488.1|WP_003857662.1|1983399_1984035_+|carbonic-anhydrase
MQHIIEGFLSFQKEIFPQRKELFRSLASSQNPKALFISCSDSRLVPELVTQQEPGQLFVIRNAGNIVPPFGPEPGGVSATIEYAVVALGVTDIVICGHSNCGAMKAIADNADLEPMPAVSHWLRYSDAAKAVVEKKTWDKPIDKVNAMVQENVFAQLSNIKTHPSVAVGLRNNAIRLHGWVYDIESGKILALDKNTKSFVSLSENPEVFFE
>NZ_CP042488.1|WP_022650933.1|1982544_1983327_+|MBL-fold-metallo-hydrolase
MITLCKTCGTAYDEQPKNCPICDDDRQYVPVTGQAWTDFDSLTTTHTNKWQQLEPQLFSIKTVPAFAINQRALLLRTPQGNVLWDCIANLDPATRALVDALGGISAIAISHPHYYTTMQEWAAAFNAPIYLHASDRQWVMRDSPAIRFWEEDALEIMPLVTLLRLGGHFAGGTVLHWQSGDGVLLAGDILQVTPGKDAVSFMWSYPNMLPLPARTVESVIGRLTGKTYQRLYGAFEGQNIPVNADEIVQRSGQKYIACLR
>NZ_CP042488.1|WP_003857665.1|1982278_1982419_-|hypothetical-protein
MEIDLDNLVFNGLDEAEERNAERLDDADKKAQAIVADDDCGDACKI
>NZ_CP042488.1|WP_022650932.1|1980815_1982222_+|DUF1996-domain-containing-protein
MKRTVLTPALSATALLLTMQAAHAGPQAHVVCSYSHTLGDDAIMMFGMPNEAMLHDFFGNVHTDAYSSRESLRTQEKTTCDNKADSSAYWAPSLKLPDGTVVKPAYQKTYYQASNVDAWPLHPFPAGLSLLAGDHHGTAPNPHITFLCANGKGYTTRTGEVCGLRKAKDAVQFNIGIQFPNCWDGVNLKPAHGLANATYDTKGQCPSAFPVKIPTVNMNIAYVLPTISSLDTSKVQLSLDPIMHGSEREERWGSLYTAHADFMNGWTEDAARFMTDLCMNRGMDCGTTVPYGYSKAKANVWLSSMEPALSQPDPQVLLVQDNWKNGGRTKNSETLSLVKFHIPPLPAGQDPALFKYRVRIFGGKVETNGADQIFFYPASNDWDPATVSWHSRPSCNYRSDAVLYLNHSREYRMVDVDKVVRKALAEGKTEISWYIGGDRQGNHYQFETGSSPQSLILMLTGFSKTPEI
>NZ_CP042488.1|WP_058691408.1|1989934_1991308_-|MdtK-family-multidrug-efflux-MATE-transporter
MQKYMIEARQLLALAIPVIVAQVAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRDRVAHQVRQGFWLAGFVSVLIMIVLWNAGYIIRAMHNIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFGSMLTYIKHARSMRDIRNDTTFSTPDWSMLTRLTQLGLPIALALFFEVTLFAVVALLVSPLGIIDVAGHQIALNFSSLMFVLPMSLAAAVTIRVGFRLGQGSTLDAQTAARTGLGVGVCMAVCTALFTVLLREQIALLYNDNPEVVTLASHLMLLAAIYQISDSIQVIGSGVLRGYKDTRSIFFITFIAYWVLGLPCGYILALTDLVVDRMGPAGFWMGFIIGLTSAAIMMMLRMRFLQRQPSTVILQRAAG
>NZ_CP042488.1|WP_003857643.1|1991533_1992175_+|riboflavin-synthase
MFTGIVQGTAKVVSIDEKPNFRTHVVELPEYMLDGIETGASIAHNGCCLTVTEINGNQISFDLMKETLRITNLGELVVGDIINVERAAKFSDEIGGHLMSGHIMTTAEVAKIVTSENNRQIWFKVQDPSLMKYILYKGFIGIDGISLTVGEVTPTRFCVHLIPETLQRTTLGAKKLGQRVNIEIDPQTQAVVDTVERVLAAKEAAIIKTVEEE
>NZ_CP042488.1|WP_003857641.1|1992206_1993355_-|cyclopropane-fatty-acyl-phospholipid-synthase
MSSSCIEEVSVPDDNWSRIVSELLGRAGITINGSSPSDPQIKHPDFFKRVLQEGSLGLGESYMDGWWECERLDMFFSSVLRAGLEKQLPRHFKDTLRIASARLFNLQSKKRAWIVGKEHYDLGNDLFSRMLDPLMQYSCGYWKKATTLEEAQQDKLQLICDKLQLQPGMRVLDIGCGWGGLAWFMAKNYGVSVVGVTISAEQQKMAQERCLGLDVDIRLQDYRDLNEQFDRIVSVGMFEHVGPKNYKTYFEVADRNLKPDGIFLLHTIGSKRTDNNVDPWINKYIFPNGCLPSVRQIANASEPHFIVEDWHNFGADYDTTLMAWHERFQAAWPEIADNYSERFKRMFSYYLNACAGAFRARDIQLWQVVFSRGIEHGLRVAR
>NZ_CP042488.1|WP_003857639.1|1993653_1994853_-|Bcr/CflA-family-multidrug-efflux-MFS-transporter
MQPRKGFLVWLGGLSVLGFLATDMYLPAFAAMQEDLQTPAAAISASLSLFLAGFAFAQLLWGPLSDRFGRKPVLLLGLAIFAAGCLGMLWVRDAAWLLALRFIQAVGVCAAAVTWQALVTDYYPASRTNRIFATIMPLVGLSPALAPLLGSWILAHFDWQAIFATLFAITLVLMLPAFGLKPAHKKETHPDAKPITFTSLLRSKAYRGNVLIYAACSASFFAWLTGSPFILHDMGYSPAAIGLSYVPQTIAFLVGGYGCRAALQKWEGQQMLPWLLVLYALSVIATWAVGFIPGAGLAEILIPFCVMAIANGAIYPIVVAQALRPFPQATGRAAALQNTLQLGLCFLASLVVSALIATPLLTTTSVMLITVALAGLGYRMQSSALREQNDNAQTETSHA
>NZ_CP042488.1|WP_058691407.1|1994965_1995877_+|LysR-family-transcriptional-regulator
MWSDYSLEVVDAVARNGSFTGAAQELHRVPSAISYTVRQLEAWLAVPLFERRHRDVELTPAGAWFLKEGRSVIKKMQITREQCQQIANGWRGHLAIAVDNIVKPERTRQMIVDFYRHFSDVELRVSQEVFNGVWDALADGRAEMAIGATQAIPVGGRYAFRDMGMLSWTCVVARDHPLAALEGPLSDDTLRNWPSLVLEDTSRSLPKRITWLLDNQRRVVAPDWESSATCLSAGLCVGMVPVHFARPRIDTGEWVALTLENPFPDAACCLTWQQNDVSPAMAWLLDYLGDSETLNREWLREPA
>NZ_CP042488.1|WP_003857634.1|1995894_1996920_-|HTH-type-transcriptional-repressor-PurR
MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNIEKQRAYLSMMAQKRVDGLLVMCSEYPESVLSMLEEYRHIPMVVMDWGEARADFTDSVIDNAFEGGYMAGRYLVERGHREIGVIPGPLERNTGAGRLAGFMKAMEEALITVPENWIVQGDFEPESGYRAMQQIVSQPHRPTAVFCGGDIMAMGALCAADELGLRVPQDISVIGYDNVRNARFFTPALTTIHQPKDSLGETAFNMLLDRIVNKREQSQSIEVHPRLIERRSVADGPFRDYRR
>NZ_CP042488.1|WP_003857632.1|1997217_1997307_+|YnhF-family-membrane-protein
MSTDLKFSLFTTIVVLALIVAGGLTAALH
>NZ_CP042488.1|WP_022650939.1|1997468_1998635_+|MFS-transporter
MKINFPLLALAIGAFGIGTTEFSPMGLLPVIARGVDVSIPAAGMLISAYAIGVMVGAPLMTLLLSHRARRNALIFLMAIFTLGNVFSAISPDYTTLMLSRILTSLNHGAFFGLGSVVAASVVPKHKQASAVATMFMGLTIANIGGVPAATWLGEAIGWRMSFLATAGLGVVAMVALFFSLPKGSAGERPEVRKELAVLMRPQVLSALLTTVLGAGAVFTLYTYISPVLHDITHATPLFVTAMLVLIGVGFSIGNYLGGKFADRSVSGTLKGFLTLLIVIMVAIPWLARNEVGAAIAMVVWGAATFAVVPPLQMRVMRVAHEAPGLSSSVNIGAFNLGNALGAAAGGAVISGGLGYSFVPVMGAIIAALGLLLVIMSGRKQPQAVCTAE
>NZ_CP042488.1|WP_003857629.1|1998672_1999254_-|superoxide-dismutase-[Fe]
MSFELPALPYAKDALAPHISAETLEYHYGKHHQTYVTNLNNLIKGTDFEGKTLEEIVRSSDGGVFNNAAQVWNHTFYWHCLAPNAGGEPDGELAAAINAAFGSFADFKAKFTDAAVKNFGSGWTWLVKEADGKLAIVSTSNAGTPLTTSATPLMTVDVWEHAYYIDYRNARPNYLEHFWALVNWEFVAKNFAA
>NZ_CP042488.1|WP_022650940.1|1999376_2000135_-|NlpC/P60-family-protein
MARITKISMTLCALLFTTLSFTPAANASEQARHSAVQKTHLAKSTERKKKTTSKTVKKKTTAQTKKTASSKTKTLRSGTHKTTRTTASLVNEKCTVRKGHKTKCAKVTKLADVHKARMQKAQKTAMNKLMGQIGKPYRWGGTSPRTGFDCSGLVYYAYKDLVKFRIPRTANEMYHLRDAAPVNRGELQNGDLVFFRTQGRGTADHVGVYVGNGKFIQSPRSGQDIQITSLSEDYWVRHYVGARRVMTPKTIR

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Crispr_ID: NZ_CP042488_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042488_3

2820741-2820823

Orphan

Consensus_repeat	Method
TGGACACTGGCTGGACACCGGCTGGACA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP042488_3

>merge|NZ_CP042488|3|2820741-2820823|CRISPRCasFinder
TGGACACTGGCTGGACACCGGCTGGACACTCCACCTCCGCAGGCATTGGTACGACTGCGTTTGGGCTGGACACTGGCTGGACA

>NZ_CP042488|3|3|2820741-2820823|CRISPRCasFinder
TGGACACTGGCTGGACACCGGCTGGACA	CTCCACCTCCGCAGGCATTGGTACGAC
TGCGTTTGGGCTGGACACTGGCTGGACA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042488.1\|WP_058656829.1\|2816503_2817088_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042488.1\|WP_058691391.1\|2821449_2821995_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368819
NZ_CP042488.1\|WP_058691389.1\|2823531_2823969_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042488.1\|WP_022651075.1\|2824760_2825045_+\|host-nuclease-inhibitor-GamL	unknown	unknown	unknown
NZ_CP042488.1\|WP_058691393.1\|2818904_2820338_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|274672
NZ_CP042488.1\|WP_042889319.1\|2814866_2815067_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042488.1\|WP_058656828.1\|2815867_2816323_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182057
NZ_CP042488.1\|WP_022651072.1\|2826582_2827011_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042488.1\|WP_001281306.1\|2824112_2824322_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042488.1\|WP_022651094.1\|2815697_2815868_-\|NinE-family-protein	unknown	unknown	gnl\|CDD\|182029
NZ_CP042488.1\|WP_058691394.1\|2817643_2818030_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042488.1\|WP_022651095.1\|2815063_2815705_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368603
NZ_CP042488.1\|WP_001514158.1\|2824478_2824688_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236900
NZ_CP042488.1\|WP_022651096.1\|2814763_2814880_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042488.1\|WP_063842486.1\|2822287_2823040_+\|LexA-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224885
NZ_CP042488.1\|WP_045897862.1\|2814077_2814767_-\|antiterminator	unknown	unknown	gnl\|CDD\|368843
NZ_CP042488.1\|WP_022651073.1\|2825905_2826586_+\|YqaJ-viral-recombinase-family-protein	unknown	unknown	gnl\|CDD\|378216
NZ_CP042488.1\|WP_058656838.1\|2817097_2817352_-\|DNA-polymerase-III-subunit-theta	unknown	unknown	gnl\|CDD\|368909
NZ_CP042488.1\|WP_000102594.1\|2822012_2822246_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042488.1\|WP_022651074.1\|2825063_2825909_+\|phage-recombination-protein-Bet	unknown	unknown	gnl\|CDD\|273871

Protein	Function_ID	Function_description	E-value
NZ_CP042488.1\|WP_058691391.1\|2821449_2821995_-\|hypothetical-protein	gnl\|CDD\|368819	pfam06254, YdaT_toxin, Putative bacterial toxin ydaT. YdaT_toxin is a family of putative bacterial toxins that are neutralized by the putative antitoxin YdaS, UniProtKB:P76063, family pfam144549.	6.94018e-36
NZ_CP042488.1\|WP_022651074.1\|2825063_2825909_+\|phage-recombination-protein-Bet	gnl\|CDD\|273871	TIGR01913, Uncharacterized_protein_UU154, phage recombination protein Bet. This model represents the phage recombination protein Bet from a number of phage, including phage lambda. All members of this family are found in phage genomes or in putative prophage regions of bacterial genomes. [Mobile and extrachromosomal element functions, Prophage functions].	2.56013e-34
NZ_CP042488.1\|WP_022651095.1\|2815063_2815705_-\|hypothetical-protein	gnl\|CDD\|368603	pfam05766, NinG, Bacteriophage Lambda NinG protein. NinG or Rap is involved in recombination. Rap (recombination adept with plasmid) increases lambda-by-plasmid recombination catalyzed by Escherichia coli's RecBCD pathway.	2.43638e-61
NZ_CP042488.1\|WP_063842486.1\|2822287_2823040_+\|LexA-family-transcriptional-regulator	gnl\|CDD\|224885	COG1974, LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms].	1.7203e-36
NZ_CP042488.1\|WP_058691393.1\|2818904_2820338_-\|AAA-family-ATPase	gnl\|CDD\|274672	TIGR03600, phage_DnaB, phage replicative helicase, DnaB family, HK022 subfamily. Members of this family are phage (or prophage-region) homologs of the bacterial homohexameric replicative helicase DnaB. Some phage may rely on host DnaB, while others encode their own verions. This model describes the largest phage-specific clade among the close homologs of DnaB, but there are, or course, other DnaB homologs from phage that fall outside the scope of this model. [Mobile and extrachromosomal element functions, Prophage functions].	0
NZ_CP042488.1\|WP_022651094.1\|2815697_2815868_-\|NinE-family-protein	gnl\|CDD\|182029	PRK09689, PRK09689, prophage protein NinE; Provisional.	1.04554e-22
NZ_CP042488.1\|WP_045897862.1\|2814077_2814767_-\|antiterminator	gnl\|CDD\|368843	pfam06323, Phage_antiter_Q, Phage antitermination protein Q. This family consists of several phage antitermination protein Q and related bacterial sequences. Phage 82 gene Q encodes a phage-specific positive regulator of late gene expression, thought, by analogy to the corresponding gene of phage lambda, to be a transcription antiterminator.	5.42664e-90
NZ_CP042488.1\|WP_058656828.1\|2815867_2816323_-\|hypothetical-protein	gnl\|CDD\|182057	PRK09741, PRK09741, hypothetical protein; Provisional.	1.89023e-90
NZ_CP042488.1\|WP_022651073.1\|2825905_2826586_+\|YqaJ-viral-recombinase-family-protein	gnl\|CDD\|378216	pfam09588, YqaJ, YqaJ-like viral recombinase domain. This protein family is found in many different bacterial species but is of viral origin. The protein forms an oligomer and functions as a processive alkaline exonuclease that digests linear double-stranded DNA in a Mg(2+)-dependent reaction, It has a preference for 5'-phosphorylated DNA ends. It thus forms part of the two-component SynExo viral recombinase functional unit.	4.99622e-32
NZ_CP042488.1\|WP_058656838.1\|2817097_2817352_-\|DNA-polymerase-III-subunit-theta	gnl\|CDD\|368909	pfam06440, DNA_pol3_theta, DNA polymerase III, theta subunit. DNA polymerase III (EC 2.7.7.7) is comprised of three tightly associated subunits, alpha, epsilon and theta. This family contains the theta subunit. The structure of the theta subunit shows that the N-terminal two thirds is comprised of three helices while the C-terminal third is disordered. The function of the theta subunit is poorly understood, but the interaction of the theta subunit with the epsilon subunit is thought to enhance the 3' to 5' exonucleolytic proofreading activity of epsilon.	1.97266e-32
NZ_CP042488.1\|WP_001514158.1\|2824478_2824688_+\|hypothetical-protein	gnl\|CDD\|236900	PRK11354, kil, FtsZ inhibitor protein; Reviewed.	1.62359e-36

>NZ_CP042488.1|WP_058691393.1|2818904_2820338_-|AAA-family-ATPase
MTADFMAVPQNLEAEQSVIGGLLLDDDNSERVQKVLAMLKPESFYSRPHQLIFAEMRQMFRDNKPVDGLTLFDALEGKGLAEQVGGFAYLAEIAKNTPSAANIVAYAASVREAAMERYGINRLTEATELLYSRNGMSATQKYEAIQGIFTQLADHSKTGSRRGLRSFGEVMDDWVADLEKRFDPSGEQRGMSTGIPSLDRLLAPKGLVKGSLFVIGARPKMGKTTLYGQMAINCAVREKKPALMFSLEMPSDQILEKLVGQKSGVNPSIFYMPATDDADDQYQGDYDGDFKKAIATAGRLSEIDMLYIDDTPGLSLAHIVTECRRIKREKGCVGMILVDYLTLMTAEKADRNDLAYGMITKGLKNLAKELGCVVVLLTQLNRELEKRVNKRPLPSDSRDTGQIEQDCDYWVGIHREGAFDDSVPPGETELILRLNRHGSTGTVYCNQINGAIYDTDQQAAAAERRGREQQPKKKGGF
>NZ_CP042488.1|WP_058691394.1|2817643_2818030_-|hypothetical-protein
MSTTLKEWLLKTIAELEEERDVTPGVVNEDAAKALAAMKLALASLEAEAMTQVLSSRAGNDTSTIDKALPEGTVLYTAPPAPVVPDAISTRQAIAQMENHEPCDSINVAYKFGWNACRAAMLQGADGI
>NZ_CP042488.1|WP_058656838.1|2817097_2817352_-|DNA-polymerase-III-subunit-theta
MNDFNIAAKSQEERDKVNVDLAASGVAYKERLNMPVIAEVVMREQPEHLRDYFLEQLRHYREESLKLPKASDPRYIEMTEANTK
>NZ_CP042488.1|WP_058656829.1|2816503_2817088_-|hypothetical-protein
MELWVGSMIGGAIGAVIGHGANHFIGWFKENKQSSPERKFICAELVFLLENYAVKCAEVVQDDGEANGEQGEYESTTKLPEKIDYSLVKGNWKSLKSKTMYEICSLPMKQNEAIKSINFVGEYMSSPPDHREYFDERQYQFSLLGLKAAEIASGIRKENGFPATELAKWVLPALEERLQKIKDKRLKYQYEEDL
>NZ_CP042488.1|WP_058656828.1|2815867_2816323_-|hypothetical-protein
MILPRGGIKLHRGNFAAIGQQIQPLLDAGQCFRLQVKPWREKRSLSQNALSHMWYMEISEYLITRGKTFATPEWVKDAMKHTYLGYESKDRVDVVSGEVTTVQSLRHTSELETGEMYIFLCKVEAWAMNIGCHLTIPQSCEYQQLRDKQEA
>NZ_CP042488.1|WP_022651094.1|2815697_2815868_-|NinE-family-protein
MSSPLSRVITNEIFRVPTRRQRKPAVKPSDIPTLKGYTARLVDQKWLRLAARRAHG
>NZ_CP042488.1|WP_022651095.1|2815063_2815705_-|hypothetical-protein
MAKLPHRKCAHKACRQWFHPVRDGQVVCSFECASAIGKEQTAKAREAAQQKETQRQRTEEKAGRQRRKARLAELRPNGYYKAQAQQAFNAYIRARDAGLPCISCGETNPPDLHGGQWDCGHFKTVGANPELRFEERNAHKQCKSCNAGAGKYTAKEATVAQQYEAGLIARYGQEYVDWLNGPHEMTNYRREDFIRIRDEYRAKLKALKQREAA
>NZ_CP042488.1|WP_042889319.1|2814866_2815067_-|hypothetical-protein
MKTFTPVEARKFVASTWYETAQLSKRERLYAKARELISGDRAEIICQTENPEYRKSAREWWNHDQS
>NZ_CP042488.1|WP_022651096.1|2814763_2814880_-|hypothetical-protein
MTRADFEKYQAESVKRANLPPVAKHSQNKTNQPQKEAA
>NZ_CP042488.1|WP_045897862.1|2814077_2814767_-|antiterminator
MNSQQLEYVRQQLIVATADLSGATKGQLVAFAENAQFTATARSRGRKKITDPVTGRKVNPDAPPMSGSQSRAKGSSIALVSPVEFGTASWRRAVLSLEEHQKAWLLWNYSENIRFEYQVAITQWAWAEFREQLGAKKVAGKTMERLKKLIWLAAQDVKAELAGRETYEYQVLAELVGVAKSTWTETYLPHWLAMRNSFKRLDSGALISATRSRSQQKATNLDISLAKPN
>NZ_CP042488.1|WP_058691391.1|2821449_2821995_-|hypothetical-protein
MHSLAYQQGNKFSPTAMIYQNRREPDSSALNIDGIRAAVRAWAADCRSREFVAALIVEEWRATGGTGLDIPTDSHRQMQKVFRWIDGDTEYAANNIRQLATAIMAVLPLDYRHRLLPEDSFMSRLARLEKETSEAKVAVAMNAPRHQKLKELSEGIVEMFRVDPDLTAPLMAMVTSMLGVM
>NZ_CP042488.1|WP_000102594.1|2822012_2822246_-|hypothetical-protein
MSTELHRWRKAATTDEWAQLAKLANTTPGYLDQIAYGNRRASPEMASAIEKGTKNFHRQAPVLKESLVFASPRDTAA
>NZ_CP042488.1|WP_063842486.1|2822287_2823040_+|LexA-family-transcriptional-regulator
MLNTTQASFSNLHIYHFAKSSNNAGMENKEIRKANLEALYEKRQHESGMTKAQFAELIETSPAALSQLLGPNPHRNIGDKMARKIETALDLPFGWMDVLHASEEPSNVAFRGLNETKGSYPVISWVSAGQWMEAVEPYHRRAIDRWYDTTVVCSDDSFWLDVKGDSMTSPAGLSIPEGAAILVDPEVEPRNGKLVVAKLEGDNEATFKKLVIDAGRRFLKPLNPAYPMIEVNGNCKIIGVVVDAKILNIP
>NZ_CP042488.1|WP_058691389.1|2823531_2823969_+|hypothetical-protein
MLGDGNTAISTAQETMILFWLDWKSLLGPPARGHFFGGCMFATDISLKYGTHQPETILETMPIEEASEIIKEKLRDEVRQELECEYGDRLYEAEEEASNWESRADDYESDATCLAKAIREAFESANFEDAMVILERAMHDHKDYF
>NZ_CP042488.1|WP_001281306.1|2824112_2824322_+|hypothetical-protein
MSDLELGLKIYALWFVGTFLLGIAINSLTKKEHRQPLSKLAIDHVRMSSAITIVGLIVCGMGWFLFKVV
>NZ_CP042488.1|WP_001514158.1|2824478_2824688_+|hypothetical-protein
MMHHYGTTPLIRQCVTPGMMAMHEGRTYRVSAVIQERKWVYLHTDAEIIRLSDCVIDVLLDGHGNPIQH
>NZ_CP042488.1|WP_022651075.1|2824760_2825045_+|host-nuclease-inhibitor-GamL
MNAYLTYDRIEDRRWVEQQLTDEKEKWIDDRAQQIIDMMPKEPSGLFHFSVPIDSSPYEGLRSDKAGEAYNDFISAVAYAQAEYDWEHRTGCPF
>NZ_CP042488.1|WP_022651074.1|2825063_2825909_+|phage-recombination-protein-Bet
MANELTITATSLQEIGVDVSTWSALKNSIYPGAKDESVMMALDYCRARQLDPLLKPVHLVPMYVKDSKTGKGDWRDVVMPGIGLYRIQADRSGDYAGAREPEFGPDVTQTLTGVEVTFPQWCKYTVYKRMPSGEIVEFSAKEYWIENYATGGRDTTAPNAMWKKRPYGQLAKCAEAQALRKAWPEIGQQPTAEEMEGKSLDVDIRDVTPRNTTEALPPAASEETLQAITDLLTTLDKDWEKDFLPLCSDIFKRQILEASELTEEEAQKGFGFLQKRAKAAA
>NZ_CP042488.1|WP_022651073.1|2825905_2826586_+|YqaJ-viral-recombinase-family-protein
MTPEIILARTGIDVTTIQQGDEAWHRLRLGVITASEVHNVISKPRSGKKWTDMKMSYFHTLLAEVCTGVAPEVNAKALAWGKQYEEDARTLFEFTTDVKVTESPILFRDESMRTACSPDGLCSNDFGLELKCPFTSRDFMKFRLGGFEAIKSAYMAQVQYSMWVTGKDAWFFANYDPRMKREGIHHVVVERDPQYMTDFNEMVPEFIEKMDEALAEIGFTFGEQWK
>NZ_CP042488.1|WP_022651072.1|2826582_2827011_+|hypothetical-protein
MKRTPFYRRPGRTGQFSGLRERVIWMIQTRGRPVTGSEIAEKFGVTLIEFNRVANGITRGTGQIAQIVETEKWLNEDGICDRKFSLASKPKVVTPQGKSRLFTRRAIEQSQEGRRQECIQRAARRRRLIAQGLYIDEMESIL

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP042488_3	3.1\|2820769\|27\|NZ_CP042488\|CRISPRCasFinder	2820769-2820795	27	MN013086	Klebsiella phage vB_Kpn_Chronis, complete genome	33543-33569	1	0.963
NZ_CP042488_3	3.1\|2820769\|27\|NZ_CP042488\|CRISPRCasFinder	2820769-2820795	27	NZ_LR134256	Klebsiella aerogenes strain NCTC9644 plasmid 3, complete sequence	1565-1591	1	0.963
NZ_CP042488_2	2.1\|1989694\|38\|NZ_CP042488\|CRISPRCasFinder	1989694-1989731	38	NZ_CP043437	Enterobacter sp. LU1 plasmid unnamed	113727-113764	2	0.947
NZ_CP042488_3	3.1\|2820769\|27\|NZ_CP042488\|CRISPRCasFinder	2820769-2820795	27	NC_017077	Selenomonas ruminantium subsp. lactilytica TAM6421 plasmid pSRC7, complete sequence	20760-20786	5	0.815

1. spacer 3.1|2820769|27|NZ_CP042488|CRISPRCasFinder matches to MN013086 (Klebsiella phage vB_Kpn_Chronis, complete genome) position: , mismatch: 1, identity: 0.963

ctccacctccgcaggcattggtacgac	CRISPR spacer
atccacctccgcaggcattggtacgac	Protospacer
 **************************

2. spacer 3.1|2820769|27|NZ_CP042488|CRISPRCasFinder matches to NZ_LR134256 (Klebsiella aerogenes strain NCTC9644 plasmid 3, complete sequence) position: , mismatch: 1, identity: 0.963

ctccacctccgcaggcattggtacgac	CRISPR spacer
ctccacctccgcaggcattggtactac	Protospacer
************************ **

3. spacer 2.1|1989694|38|NZ_CP042488|CRISPRCasFinder matches to NZ_CP043437 (Enterobacter sp. LU1 plasmid unnamed) position: , mismatch: 2, identity: 0.947

cagacgcaagatggtgcgttcaattggactcgaaccaa	CRISPR spacer
cagacgcagaatggtgcgttcaattggactcgaaccaa	Protospacer
********..****************************

4. spacer 3.1|2820769|27|NZ_CP042488|CRISPRCasFinder matches to NC_017077 (Selenomonas ruminantium subsp. lactilytica TAM6421 plasmid pSRC7, complete sequence) position: , mismatch: 5, identity: 0.815

ctccacctccgcaggcattggtacgac	CRISPR spacer
tggcacctccgcaggcattggtgcggc	Protospacer
.  *******************.**.*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

434733 : 479591

Enterobacteria_phage(36.36%)

integrase,transposase

attL 428442:428457|attR 483852:483867

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
428442:428457	attL	NA	NA	NA	NA
WP_104009829.1\|434733_434967_+\|transposase	Tn3 family transposase	Q1MVP5	Enterobacteria_phage	5.8e-10	80.0
WP_151550363.1\|434979_435159_-	DUF1471 domain-containing protein	NA	NA	NA	NA
WP_016154441.1\|435489_435840_+	DUF3147 family protein	NA	NA	NA	NA
WP_085954962.1\|436821_437971_+\|transposase	IS3 family transposase	U5P429	Shigella_phage	9.8e-50	41.6
WP_009652402.1\|438556_438799_+	DUF1471 domain-containing protein	NA	NA	NA	NA
WP_016154439.1\|440725_441055_+	hypothetical protein	NA	NA	NA	NA
WP_000156887.1\|441372_442395_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_009654824.1\|442859_443996_-	hypothetical protein	A0A2H4J138	uncultured_Caudovirales_phage	5.6e-74	43.6
WP_016154438.1\|443988_444615_-	hypothetical protein	A0A2H4J137	uncultured_Caudovirales_phage	5.7e-44	42.6
WP_009654821.1\|445891_448030_+	AAA family ATPase	NA	NA	NA	NA
WP_016154436.1\|448310_448559_+	hypothetical protein	NA	NA	NA	NA
WP_016154435.1\|448943_449306_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_009654826.1\|449351_450356_-	cation diffusion facilitator family transporter	A0A1V0SED0	Indivirus	7.8e-19	25.1
WP_009654818.1\|450541_453037_+	copper-translocating P-type ATPase	A0A218MNH6	uncultured_virus	2.0e-92	34.6
WP_016154433.1\|453050_453515_+	Cu(I)-responsive transcriptional regulator	NA	NA	NA	NA
WP_009654812.1\|453604_454057_-	Cd(II)/Pb(II)-responsive transcriptional regulator	NA	NA	NA	NA
WP_016154432.1\|454138_456634_+	heavy metal translocating P-type ATPase	E4ZFI9	Streptococcus_phage	3.9e-144	45.8
WP_071687229.1\|456708_457131_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_009654822.1\|457120_457384_+	hypothetical protein	NA	NA	NA	NA
WP_023302364.1\|457696_458644_+	UDP-3-O-acyl-N-acetylglucosamine deacetylase	NA	NA	NA	NA
WP_023336667.1\|458863_459298_+	Cu(I)-responsive transcriptional regulator	NA	NA	NA	NA
WP_023302365.1\|459447_462888_+	molybdopterin-dependent oxidoreductase	NA	NA	NA	NA
WP_016154430.1\|463933_464386_-	peptide deformylase	Q6VT21	Vibrio_phage	7.8e-11	32.6
WP_016154429.1\|464562_465930_-	outer membrane porin, OprD family	NA	NA	NA	NA
WP_016154425.1\|467340_467553_-	DUF1471 domain-containing protein	NA	NA	NA	NA
WP_016154424.1\|467979_468717_-	hypothetical protein	U5N3V8	Enterobacteria_phage	9.7e-27	32.6
WP_094898333.1\|471050_472290_+\|transposase	IS3 family transposase	Q6H9S3	Enterobacteria_phage	1.4e-131	79.4
WP_016154418.1\|472742_474704_-	DUF3732 domain-containing protein	NA	NA	NA	NA
WP_016154417.1\|474700_475189_-	hypothetical protein	NA	NA	NA	NA
WP_016154416.1\|475185_476409_-	hypothetical protein	NA	NA	NA	NA
WP_016154415.1\|476976_477999_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_016154414.1\|478400_479591_-\|integrase	tyrosine-type recombinase/integrase	Q7M297	Enterobacteria_phage	1.5e-122	54.7
483852:483867	attR	NA	NA	NA	NA

DBSCAN-SWA_2

1019205 : 1026800

Enterobacteria_phage(30.0%)

integrase

attL 1011621:1011635|attR 1037308:1037322

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1011621:1011635	attL	NA	NA	NA	NA
WP_003863199.1\|1019205_1020258_-	phosphoporin PhoE	Q1MVN1	Enterobacteria_phage	2.6e-118	60.9
WP_003863197.1\|1020563_1021667_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.7e-59	39.9
WP_003863195.1\|1021678_1022932_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	2.3e-97	46.6
WP_058647473.1\|1023133_1024297_-\|integrase	site-specific integrase	A0A220NQU7	Salmonella_phage	7.7e-220	95.3
WP_003863191.1\|1024173_1024524_-	helix-turn-helix domain-containing protein	Q5G8V4	Enterobacteria_phage	1.5e-57	95.7
WP_003863189.1\|1024526_1024736_-	hypothetical protein	A0A220IH74	Escherichia_phage	2.1e-11	59.3
WP_032628143.1\|1024772_1025321_-	hypothetical protein	E5AGD3	Erwinia_phage	2.3e-20	35.0
WP_003863184.1\|1025329_1025530_-	hypothetical protein	G8C7S1	Escherichia_phage	1.1e-20	71.2
WP_022650432.1\|1025538_1026339_-	hypothetical protein	K7P7Q8	Enterobacteria_phage	6.6e-138	85.0
WP_022650433.1\|1026338_1026800_-	VUT family protein	A0A2H4N7D9	Pectobacterium_phage	4.1e-39	55.7
1037308:1037322	attR	NA	NA	NA	NA

DBSCAN-SWA_3

2096592 : 2103841

Escherichia_phage(83.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_022651054.1\|2096592_2097270_+	type A chloramphenicol O-acetyltransferase	G3CFL0	Escherichia_phage	1.5e-77	62.6
WP_032609101.1\|2097445_2097757_-	DNA damage-inducible protein	NA	NA	NA	NA
WP_017384547.1\|2097866_2098481_-	Tat proofreading chaperone DmsD	A0A077SLS7	Escherichia_phage	3.3e-28	34.7
WP_058691340.1\|2098525_2099380_-	dimethylsulfoxide reductase	A0A077SK59	Escherichia_phage	3.4e-23	34.6
WP_003858259.1\|2099381_2099999_-	dimethylsulfoxide reductase subunit B	A0A077SL61	Escherichia_phage	1.4e-74	59.1
WP_058691425.1\|2100009_2102448_-	dimethyl sulfoxide reductase subunit A	A0A077SK27	Escherichia_phage	1.7e-216	49.5
WP_003857424.1\|2102578_2102884_-	DUF1161 domain-containing protein	NA	NA	NA	NA
WP_003857421.1\|2102986_2103841_-	benzoate transporter	M1I711	Paramecium_bursaria_Chlorella_virus	8.1e-25	33.2

DBSCAN-SWA_4

2423111 : 2499764

Enterobacteria_phage(28.3%)

tRNA,plate,integrase,tail,terminase,holin

attL 2421752:2421767|attR 2447279:2447294

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2421752:2421767	attL	NA	NA	NA	NA
WP_003856933.1\|2423111_2424272_+	porin OmpS2	Q1MVN1	Enterobacteria_phage	2.5e-117	59.3
WP_022651250.1\|2424306_2424729_-	GFA family protein	NA	NA	NA	NA
WP_003856931.1\|2424732_2424930_-	hypothetical protein	NA	NA	NA	NA
WP_071785691.1\|2425350_2425551_+\|integrase	tyrosine-type recombinase/integrase	A0A0U2JGI6	Escherichia_phage	1.1e-20	71.7
WP_022651252.1\|2425875_2426565_+	SOS response-associated peptidase	A0A2H4J5W2	uncultured_Caudovirales_phage	1.1e-77	59.0
WP_071787990.1\|2426602_2426815_-	cold shock-like protein CspF	NA	NA	NA	NA
WP_022651253.1\|2427097_2427316_+	cold-shock protein	A0A1W6JNX5	Morganella_phage	2.9e-19	65.7
WP_032645629.1\|2427877_2428105_+	hypothetical protein	NA	NA	NA	NA
WP_022651254.1\|2428309_2428648_+	hypothetical protein	NA	NA	NA	NA
WP_022651255.1\|2429062_2429629_-	recombinase family protein	A0A1S6L009	Salmonella_phage	6.0e-77	80.0
WP_104468396.1\|2429711_2430542_+\|tail	tail fiber domain-containing protein	A0A192Y7T9	Enterobacteria_phage	8.4e-35	30.6
WP_022651260.1\|2431401_2432664_-	hypothetical protein	K7PM99	Enterobacterial_phage	3.2e-147	65.9
WP_022651261.1\|2432722_2432956_-	hypothetical protein	E4WL42	Enterobacteria_phage	9.5e-29	76.3
WP_022651262.1\|2433024_2433735_-	hypothetical protein	A0A2P0WA07	Enterobacter_phage	3.6e-87	72.6
WP_022651263.1\|2433735_2434050_-	hypothetical protein	A0A2P0WA17	Enterobacter_phage	6.6e-33	65.7
WP_058691451.1\|2434090_2437642_-	DUF1983 domain-containing protein	K7P840	Enterobacteria_phage	0.0e+00	84.6
WP_022651265.1\|2437694_2438321_-\|tail	tail assembly protein	K7PH91	Enterobacterial_phage	1.8e-53	59.9
WP_123839386.1\|2438432_2438999_-	hypothetical protein	NA	NA	NA	NA
WP_022651267.1\|2439075_2439789_-\|tail	phage tail protein	K7PLS6	Enterobacteria_phage	1.0e-142	97.4
WP_022651268.1\|2439790_2440546_-\|tail	phage minor tail protein L	G8C7J7	Escherichia_phage	2.0e-115	77.2
WP_022651269.1\|2440542_2440890_-\|tail	phage tail protein	I6PBN7	Cronobacter_phage	1.7e-37	62.6
WP_020690998.1\|2440946_2441300_-	hypothetical protein	A0A1V0E5P9	Salmonella_phage	6.0e-59	98.3
WP_022651270.1\|2441374_2444287_-\|tail	phage tail tape measure protein	A0A0K0VLY2	Klebsiella_phage	1.6e-128	34.7
WP_032645632.1\|2444283_2444598_-	hypothetical protein	I6PD79	Cronobacter_phage	1.1e-16	65.0
WP_022651271.1\|2444594_2444906_-	hypothetical protein	I6PDG2	Cronobacter_phage	1.8e-35	68.0
WP_022651272.1\|2444971_2445643_-	hypothetical protein	I6PBN6	Cronobacter_phage	7.4e-50	47.3
WP_022651273.1\|2445712_2446123_-	hypothetical protein	I6PDJ8	Cronobacter_phage	1.9e-32	52.2
WP_022651274.1\|2446119_2446704_-	hypothetical protein	G8C7Q1	Escherichia_phage	1.4e-49	55.3
WP_022651275.1\|2446705_2447056_-	hypothetical protein	I6PD77	Cronobacter_phage	2.1e-32	57.8
WP_022651276.1\|2447057_2447540_-	hypothetical protein	A0A0E3GMJ4	Enterobacteria_phage	2.6e-12	34.7
2447279:2447294	attR	NA	NA	NA	NA
WP_039268908.1\|2447857_2448811_-	Ig domain-containing protein	A0A1B0VMF8	Pseudomonas_phage	5.3e-134	75.0
WP_022651278.1\|2448823_2449594_-	hypothetical protein	A0A1B0VMG1	Pseudomonas_phage	6.3e-69	59.6
WP_022651279.1\|2449674_2450772_-	hypothetical protein	I6PD76	Cronobacter_phage	1.8e-117	57.9
WP_022651280.1\|2450773_2452162_-	DUF4055 domain-containing protein	A0A1B0VMH0	Pseudomonas_phage	2.1e-123	49.2
WP_022651281.1\|2452163_2453471_-	hypothetical protein	A0A1B1P9C9	Acinetobacter_phage	1.3e-143	57.3
WP_022651282.1\|2453448_2454447_-\|terminase	terminase small subunit	I6X6R5	Burkholderia_virus	1.1e-38	43.4
WP_032645635.1\|2454493_2454943_-	hypothetical protein	NA	NA	NA	NA
WP_032645710.1\|2456663_2456939_-	hypothetical protein	G8C7W1	Escherichia_phage	3.7e-32	84.4
WP_022651285.1\|2456946_2457576_-	glycoside hydrolase family 19 protein	G8C7W0	Escherichia_phage	2.3e-101	87.1
WP_022651286.1\|2457575_2457857_-\|holin	phage holin family protein	K7PKN9	Enterobacterial_phage	1.3e-19	46.2
WP_015570936.1\|2457843_2458230_-	hypothetical protein	A0A192Y8P2	Salmonella_phage	3.2e-45	78.1
WP_022651287.1\|2458323_2458512_-	hypothetical protein	NA	NA	NA	NA
WP_022651288.1\|2459015_2459207_-	hypothetical protein	NA	NA	NA	NA
WP_022651290.1\|2459732_2460566_-	antitermination protein	K7PKS8	Enterobacteria_phage	3.3e-124	78.7
WP_032645711.1\|2460562_2460925_-	RusA family crossover junction endodeoxyribonuclease	K7PM48	Enterobacteria_phage	5.2e-50	83.1
WP_071787980.1\|2460927_2461128_-	hypothetical protein	H6WRY8	Salmonella_phage	9.0e-28	78.8
WP_022651293.1\|2461132_2461735_-	DUF1367 family protein	A0A0M4QX23	Salmonella_phage	6.8e-95	82.5
WP_071605448.1\|2461774_2461972_-	hypothetical protein	K7PHG9	Enterobacteria_phage	1.4e-20	70.5
WP_022651294.1\|2462123_2462348_-	DinI family protein	H6WRY5	Salmonella_phage	1.8e-21	62.3
WP_022651295.1\|2462718_2463165_-	VOC family protein	NA	NA	NA	NA
WP_039268909.1\|2463651_2464833_+	diguanylate phosphodiesterase	NA	NA	NA	NA
WP_014884019.1\|2465178_2465397_-	hypothetical protein	NA	NA	NA	NA
WP_014832179.1\|2465698_2466148_-	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_014832180.1\|2466255_2466438_-	hypothetical protein	NA	NA	NA	NA
WP_014884021.1\|2466424_2467111_-	hypothetical protein	G8C7U6	Escherichia_phage	5.2e-83	63.4
WP_022651298.1\|2467107_2467965_-	phage replication protein O domain	K7PGZ0	Enterobacteria_phage	3.1e-101	70.1
WP_039268913.1\|2468109_2468661_-	hypothetical protein	K7PJT7	Enterobacteria_phage	7.5e-32	47.3
WP_022651300.1\|2468663_2468891_-	hypothetical protein	A0A0M4QX15	Salmonella_phage	1.6e-20	62.2
WP_022651301.1\|2468990_2469383_+	helix-turn-helix domain-containing protein	K7PM35	Enterobacteria_phage	6.3e-41	63.1
WP_039268914.1\|2470201_2473339_+	exodeoxyribonuclease	K7P6V4	Enterobacteria_phage	0.0e+00	64.4
WP_022651303.1\|2473348_2474434_+	recombinase RecT	K7PKR8	Enterobacteria_phage	2.8e-123	63.3
WP_020882485.1\|2474472_2474715_+	DUF4060 family protein	K7PHF4	Enterobacteria_phage	1.3e-33	93.6
WP_022651304.1\|2474779_2474992_+	hypothetical protein	A0A0U2RY08	Escherichia_phage	4.3e-20	63.4
WP_022651305.1\|2474993_2476232_+	DUF3596 domain-containing protein	A0A0U2JGI6	Escherichia_phage	4.3e-168	70.0
WP_003856923.1\|2476281_2477217_+\|tRNA	tRNA 2-thiocytidine(32) synthetase TtcA	A0A0U2S5Z2	Escherichia_phage	3.0e-142	95.7
WP_003856922.1\|2477260_2478634_-	ATP-dependent RNA helicase DbpA	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	1.1e-50	31.6
WP_099725433.1\|2478982_2479180_+	hypothetical protein	NA	NA	NA	NA
WP_003856916.1\|2479118_2480102_-	zinc transporter ZntB	NA	NA	NA	NA
WP_032609312.1\|2480192_2481164_-	chemoreceptor protein	A0A2H4J162	uncultured_Caudovirales_phage	2.2e-10	28.6
WP_003856913.1\|2481639_2482128_-	hypothetical protein	NA	NA	NA	NA
WP_022651307.1\|2482156_2483473_-	type VI secretion system protein VasL	NA	NA	NA	NA
WP_022651308.1\|2483496_2483952_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_003856903.1\|2485097_2485622_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_123839387.1\|2486185_2486461_-	hypothetical protein	NA	NA	NA	NA
WP_022651310.1\|2486506_2486980_-	hypothetical protein	NA	NA	NA	NA
WP_022651313.1\|2489609_2490617_-	hypothetical protein	NA	NA	NA	NA
WP_039268915.1\|2490606_2493069_-	type VI secretion system tip protein VgrG	NA	NA	NA	NA
WP_022651315.1\|2493073_2493598_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_022651316.1\|2493633_2494716_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_022651318.1\|2495048_2495540_-	hypothetical protein	NA	NA	NA	NA
WP_022651321.1\|2497994_2499764_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA

DBSCAN-SWA_5

2780352 : 2832734

Cronobacter_phage(32.14%)

tail,integrase,terminase,head,holin

attL 2782266:2782294|attR 2830521:2830549

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003859884.1\|2780352_2780997_-	protein-serine/threonine phosphatase	A0A222YWF0	Escherichia_phage	3.3e-55	49.8
WP_003859879.1\|2781164_2782145_+	DUF535 domain-containing protein	NA	NA	NA	NA
2782266:2782294	attL	NA	NA	NA	NA
WP_047724439.1\|2782622_2783294_+	SOS response-associated peptidase	A0A2H4J5W2	uncultured_Caudovirales_phage	2.6e-79	60.0
WP_032666022.1\|2783360_2783768_-	cell envelope integrity/translocation protein TolA	NA	NA	NA	NA
WP_003859872.1\|2783910_2785179_-	Y-family DNA polymerase	I6RSM4	Salmonella_phage	3.4e-229	91.5
WP_003859869.1\|2785178_2785484_-	hypothetical protein	I6PCW5	Cronobacter_phage	7.8e-15	40.6
WP_003859867.1\|2785596_2785959_+	GtrA family protein	U5P0S6	Shigella_phage	4.4e-49	85.0
WP_003859865.1\|2785955_2786885_+	glycosyltransferase family 2 protein	U5P087	Shigella_phage	5.7e-157	90.1
WP_039268929.1\|2786877_2788188_+	hypothetical protein	NA	NA	NA	NA
WP_003859861.1\|2788867_2791291_-	SGNH/GDSL hydrolase family protein	G0XNW5	Escherichia_phage	3.5e-142	39.8
WP_058691536.1\|2791346_2793824_-\|tail	phage tail protein	F1C5A7	Cronobacter_phage	0.0e+00	92.8
WP_058691537.1\|2793810_2794176_-	NlpC/P60 family protein	F1C5F2	Cronobacter_phage	7.8e-62	89.1
WP_015571561.1\|2794189_2794660_-	hypothetical protein	F1C5F1	Cronobacter_phage	1.0e-66	80.1
WP_058691538.1\|2794659_2795163_-	hypothetical protein	F1C5F0	Cronobacter_phage	1.1e-82	85.0
WP_058691539.1\|2795162_2797487_-	tape measure protein	A0A1B1W284	Salmonella_phage	7.3e-153	51.9
WP_058691540.1\|2797544_2797919_-	hypothetical protein	A0A0M4QWT0	Salmonella_phage	8.7e-24	52.4
WP_058691541.1\|2797991_2798735_-	hypothetical protein	G0ZNE7	Cronobacter_phage	1.9e-62	52.2
WP_047724454.1\|2798785_2799541_-	Ig domain-containing protein	G0ZNE6	Cronobacter_phage	9.9e-59	53.4
WP_047724455.1\|2799599_2799983_-	hypothetical protein	F1C5E4	Cronobacter_phage	2.9e-38	56.7
WP_047724457.1\|2799979_2800348_-	hypothetical protein	F1C5E3	Cronobacter_phage	3.0e-45	74.6
WP_047724459.1\|2800350_2800701_-	hypothetical protein	G0ZNE2	Cronobacter_phage	4.0e-39	67.0
WP_047724461.1\|2800700_2800874_-	hypothetical protein	Q5G8X7	Enterobacteria_phage	1.0e-11	49.1
WP_047724463.1\|2800873_2801254_-	hypothetical protein	F1C5E2	Cronobacter_phage	5.3e-29	54.5
WP_058691543.1\|2801256_2801622_-	hypothetical protein	NA	NA	NA	NA
WP_014884000.1\|2801631_2802729_-	hypothetical protein	F1C5E1	Cronobacter_phage	7.6e-161	77.7
WP_047724469.1\|2802738_2803173_-	hypothetical protein	F1C5E0	Cronobacter_phage	5.1e-52	74.3
WP_047724471.1\|2803176_2804373_-	DUF2213 domain-containing protein	F1C5D9	Cronobacter_phage	7.7e-90	48.3
WP_047724474.1\|2804418_2804775_+	hypothetical protein	NA	NA	NA	NA
WP_123971085.1\|2804976_2805327_-	hypothetical protein	NA	NA	NA	NA
WP_072058656.1\|2805425_2806424_-\|head	phage head morphogenesis protein	F1C5D8	Cronobacter_phage	3.9e-111	67.1
WP_047724482.1\|2806371_2807832_-	DUF1073 domain-containing protein	F1C5D7	Cronobacter_phage	9.4e-199	74.6
WP_047724485.1\|2807843_2809316_-\|terminase	terminase	A0A1W6JNY3	Morganella_phage	5.7e-252	83.7
WP_003859854.1\|2809315_2809834_-	hypothetical protein	A0A2H4J2I6	uncultured_Caudovirales_phage	3.9e-46	58.2
WP_151550382.1\|2810053_2810284_-	hypothetical protein	NA	NA	NA	NA
WP_047718953.1\|2810489_2810753_-	hypothetical protein	NA	NA	NA	NA
WP_003859849.1\|2810883_2811402_-	Rha family transcriptional regulator	Q38450	Enterobacteria_phage	6.1e-92	98.2
WP_003859846.1\|2811871_2812150_-	hypothetical protein	NA	NA	NA	NA
WP_003859844.1\|2812146_2812689_-	glycoside hydrolase family 108 protein	A0A0U2S643	Escherichia_phage	1.2e-74	70.4
WP_001514184.1\|2812691_2812967_-\|holin	phage holin family protein	S4TNV9	Salmonella_phage	5.8e-09	41.0
WP_001514183.1\|2812963_2813365_-	hypothetical protein	NA	NA	NA	NA
WP_003859838.1\|2813645_2813888_-	hypothetical protein	NA	NA	NA	NA
WP_045897862.1\|2814077_2814767_-	antiterminator	I6PDF8	Cronobacter_phage	2.5e-56	52.7
WP_022651096.1\|2814763_2814880_-	hypothetical protein	NA	NA	NA	NA
WP_042889319.1\|2814866_2815067_-	hypothetical protein	K9L458	Pectobacterium_phage	1.5e-06	60.4
WP_022651095.1\|2815063_2815705_-	hypothetical protein	M9NYX8	Enterobacteria_phage	2.9e-75	70.7
WP_022651094.1\|2815697_2815868_-	NinE family protein	G8C7V4	Escherichia_phage	7.7e-20	85.5
WP_058656828.1\|2815867_2816323_-	hypothetical protein	I6PD71	Cronobacter_phage	5.9e-59	66.2
WP_058656829.1\|2816503_2817088_-	hypothetical protein	NA	NA	NA	NA
WP_058656838.1\|2817097_2817352_-	DNA polymerase III subunit theta	G8C7V1	Escherichia_phage	1.1e-27	77.5
WP_058691394.1\|2817643_2818030_-	hypothetical protein	M9NZE4	Enterobacteria_phage	2.2e-22	57.3
WP_058691393.1\|2818904_2820338_-	AAA family ATPase	Q716D2	Shigella_phage	4.1e-231	86.9
WP_058691392.1\|2820327_2821227_-	hypothetical protein	Q8VNP8	Enterobacteria_phage	1.9e-80	55.1
WP_058691391.1\|2821449_2821995_-	hypothetical protein	G8C7U3	Escherichia_phage	1.1e-78	81.8
WP_000102594.1\|2822012_2822246_-	hypothetical protein	A0A0P0ZDD7	Stx2-converting_phage	2.6e-18	62.3
WP_063842486.1\|2822287_2823040_+	LexA family transcriptional regulator	A0A286S2B2	Klebsiella_phage	2.7e-72	64.0
WP_058691389.1\|2823531_2823969_+	hypothetical protein	K7P7N6	Enterobacteria_phage	1.8e-76	97.2
WP_001281306.1\|2824112_2824322_+	hypothetical protein	NA	NA	NA	NA
WP_001514158.1\|2824478_2824688_+	hypothetical protein	M9NZE2	Enterobacteria_phage	1.3e-32	92.8
WP_022651075.1\|2824760_2825045_+	host nuclease inhibitor GamL	G8C7T1	Escherichia_phage	1.0e-48	96.8
WP_022651074.1\|2825063_2825909_+	phage recombination protein Bet	A0A1I9KF88	Aeromonas_phage	1.1e-69	61.2
WP_022651073.1\|2825905_2826586_+	YqaJ viral recombinase family protein	M9NZE1	Enterobacteria_phage	2.0e-127	95.6
WP_022651072.1\|2826582_2827011_+	hypothetical protein	G8C7S8	Escherichia_phage	4.9e-71	93.7
WP_022651071.1\|2827007_2827160_+	DUF1317 family protein	T1SAR0	Salmonella_phage	1.6e-05	44.2
WP_022651070.1\|2827156_2827708_+	phage N-6-adenine-methyltransferase	E5AGF8	Erwinia_phage	4.8e-55	58.9
WP_032621601.1\|2827704_2827923_+	hypothetical protein	NA	NA	NA	NA
WP_006176201.1\|2827919_2828150_+	hypothetical protein	S4TRP7	Salmonella_phage	1.3e-06	39.7
WP_058656544.1\|2828241_2828460_+	TraR/DksA family transcriptional regulator	A0A0N7C211	Escherichia_phage	5.4e-18	63.9
WP_058656543.1\|2828459_2828699_+	DUF4222 domain-containing protein	Q6H9Z8	Enterobacteria_phage	9.8e-13	52.6
WP_045617122.1\|2828704_2828917_-	hypothetical protein	NA	NA	NA	NA
WP_023300430.1\|2829119_2829392_+	hypothetical protein	A0A2H4J5E1	uncultured_Caudovirales_phage	2.9e-29	64.4
WP_058691373.1\|2829360_2830446_+\|integrase	tyrosine-type recombinase/integrase	A0A2H4IYC8	uncultured_Caudovirales_phage	7.3e-148	68.4
WP_003859787.1\|2830768_2831107_-	YebY family protein	NA	NA	NA	NA
2830521:2830549	attR	NA	NA	NA	NA
WP_022651438.1\|2831123_2831993_-	copper homeostasis membrane protein CopD	NA	NA	NA	NA
WP_022651439.1\|2831994_2832366_-	CopC domain-containing protein YobA	NA	NA	NA	NA
WP_003859784.1\|2832503_2832734_+	DNA polymerase III subunit theta	H9C187	Pectobacterium_phage	7.0e-16	61.8

DBSCAN-SWA_6

2861434 : 2956054

103

Vibrio_phage(15.56%)

coat,portal,tRNA,plate,tail,terminase,integrase,holin,protease

attL 2888268:2888284|attR 2960721:2960737

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003859730.1\|2861434_2863168_+\|tRNA	arginine--tRNA ligase	A0A1V0SIS8	Klosneuvirus	8.8e-87	37.0
WP_003859729.1\|2863202_2864342_-	glycoside hydrolase family 105 protein	NA	NA	NA	NA
WP_003859727.1\|2864346_2865930_-	MFS transporter	NA	NA	NA	NA
WP_003859725.1\|2866191_2866584_-	flagellar protein FlhE	NA	NA	NA	NA
WP_003859723.1\|2866583_2868662_-	flagellar biosynthesis protein FlhA	NA	NA	NA	NA
WP_003859720.1\|2868654_2869803_-	flagellar type III secretion system protein FlhB	NA	NA	NA	NA
WP_003859718.1\|2869953_2870598_-	protein phosphatase CheZ	NA	NA	NA	NA
WP_000763862.1\|2870608_2870998_-	chemotaxis protein CheY	Q56AR1	Bacillus_thuringiensis_phage	1.3e-06	31.3
WP_003859716.1\|2871015_2872065_-	chemotaxis response regulator protein-glutamate methylesterase	Q56AR1	Bacillus_thuringiensis_phage	2.3e-05	32.0
WP_003859714.1\|2872061_2872928_-	protein-glutamate O-methyltransferase CheR	NA	NA	NA	NA
WP_022651450.1\|2872947_2874549_-	methyl-accepting chemotaxis protein IV	A0A2H4J162	uncultured_Caudovirales_phage	2.2e-07	77.3
WP_022651451.1\|2874593_2876261_-	methyl-accepting chemotaxis protein II	A0A2H4J162	uncultured_Caudovirales_phage	5.8e-11	34.7
WP_022651452.1\|2876346_2877309_-\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_022651453.1\|2877305_2879690_-	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_022651454.1\|2879665_2880427_-	molecular chaperone	NA	NA	NA	NA
WP_032609535.1\|2880443_2880992_-\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_003859701.1\|2880999_2881572_-	polyketide synthase	NA	NA	NA	NA
WP_003859700.1\|2881997_2883257_+	dicarboxylate/amino acid:cation symporter	NA	NA	NA	NA
WP_003859699.1\|2883302_2883806_-	chemotaxis protein CheW	NA	NA	NA	NA
WP_003859698.1\|2883825_2885835_-	chemotaxis protein CheA	NA	NA	NA	NA
WP_003859697.1\|2885839_2886769_-	flagellar motor protein MotB	NA	NA	NA	NA
WP_003859696.1\|2886765_2887653_-	flagellar motor stator protein MotA	NA	NA	NA	NA
WP_003859695.1\|2887776_2888355_-	flagellar transcriptional regulator FlhC	NA	NA	NA	NA
2888268:2888284	attL	NA	NA	NA	NA
WP_006811111.1\|2888357_2888717_-	flagellar transcriptional regulator FlhD	NA	NA	NA	NA
WP_003859692.1\|2889504_2889933_+	universal stress protein UspC	NA	NA	NA	NA
WP_003859691.1\|2889948_2891373_-	alpha,alpha-trehalose-phosphate synthase	NA	NA	NA	NA
WP_003859690.1\|2891347_2892151_-	trehalose-phosphatase	NA	NA	NA	NA
WP_003859689.1\|2892304_2893285_-	L-arabinose ABC transporter permease AraH	NA	NA	NA	NA
WP_003859688.1\|2893299_2894814_-	L-arabinose ABC transporter ATP-binding protein AraG	A0A285PWH2	Cedratvirus	3.1e-11	28.7
WP_003859687.1\|2894885_2895875_-	arabinose ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_003859686.1\|2896191_2896749_-	DJ-1/PfpI family protein	NA	NA	NA	NA
WP_003859685.1\|2897251_2897755_+	non-heme ferritin-like protein	NA	NA	NA	NA
WP_003859684.1\|2898329_2899673_+	anaerobic C4-dicarboxylate transporter	NA	NA	NA	NA
WP_003859683.1\|2899753_2900005_-	DUF2766 domain-containing protein	NA	NA	NA	NA
WP_003859682.1\|2900111_2900195_-	stress response protein AzuC	NA	NA	NA	NA
WP_003859681.1\|2900409_2901828_+	MFS transporter	NA	NA	NA	NA
WP_003859680.1\|2901871_2902510_-	RpiB/LacA/LacB family sugar-phosphate isomerase	NA	NA	NA	NA
WP_003859678.1\|2902755_2903094_+	hypothetical protein	NA	NA	NA	NA
WP_003859676.1\|2903294_2903792_+	non-heme ferritin	NA	NA	NA	NA
WP_003859673.1\|2903828_2904065_-	YecH family protein	NA	NA	NA	NA
WP_032645646.1\|2904256_2905468_+	tyrosine transporter TyrP	NA	NA	NA	NA
WP_003859671.1\|2905784_2906453_-	YecA family protein	NA	NA	NA	NA
WP_058691492.1\|2906864_2907986_+	branched-chain amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_003859667.1\|2908053_2908968_+	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_003859664.1\|2908979_2910254_+	high-affinity branched-chain amino acid ABC transporter permease LivM	NA	NA	NA	NA
WP_003859662.1\|2910250_2911126_+	ATP-binding cassette domain-containing protein	NA	NA	NA	NA
WP_003859661.1\|2911122_2911839_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.0e-12	28.5
WP_003859658.1\|2912002_2912473_+	hypothetical protein	NA	NA	NA	NA
WP_022651459.1\|2912478_2913405_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_003859653.1\|2913434_2913758_-	hypothetical protein	NA	NA	NA	NA
WP_099516328.1\|2913836_2913938_-	DNA invertase	NA	NA	NA	NA
WP_047737708.1\|2914641_2915238_+	Rha family transcriptional regulator	Q8H9L9	Vibrio_phage	1.7e-29	61.0
WP_004157630.1\|2915746_2915902_+	type II toxin-antitoxin system HicA family toxin	A0A0D4DC32	Acinetobacter_phage	1.2e-16	78.4
WP_047737705.1\|2915923_2916334_+	type II toxin-antitoxin system HicB family antitoxin	A0A0D4DCG1	Acinetobacter_phage	3.2e-35	53.4
WP_058691493.1\|2916415_2916982_+	serine acetyltransferase	NA	NA	NA	NA
WP_063842524.1\|2916985_2917408_-\|tail	tail fiber assembly protein	U5P083	Shigella_phage	3.4e-24	45.7
WP_045345258.1\|2919553_2920105_-\|tail	phage tail protein I	A0A0F7LDF3	Escherichia_phage	3.3e-27	41.0
WP_058691495.1\|2920097_2921012_-\|plate	baseplate assembly protein	A0A088FQL4	Escherichia_phage	6.3e-68	50.3
WP_058691496.1\|2920995_2921349_-\|plate	baseplate assembly protein	E5FFH4	Burkholderia_phage	5.0e-21	50.0
WP_058691497.1\|2921386_2922505_-	late control protein D	R9TNM7	Vibrio_phage	4.1e-37	33.1
WP_058691498.1\|2922507_2922723_-\|tail	phage tail protein	R9TR63	Vibrio_phage	6.7e-13	52.9
WP_053070193.1\|2922697_2923168_-\|tail	phage tail protein	D4HTW5	Vibrio_phage	2.4e-15	34.1
WP_058691499.1\|2923164_2925162_-	hypothetical protein	A0A2I7R3J9	Vibrio_phage	3.1e-27	31.7
WP_023299869.1\|2925276_2925564_-\|tail	phage tail assembly protein	NA	NA	NA	NA
WP_023299868.1\|2925615_2926122_-\|tail	phage major tail tube protein	NA	NA	NA	NA
WP_023299867.1\|2926118_2927588_-	hypothetical protein	R9TMQ0	Vibrio_phage	1.2e-76	46.8
WP_023299866.1\|2927626_2928250_-\|plate	phage baseplate assembly protein V	Q8HAB9	Salmonella_phage	5.5e-07	30.8
WP_023299865.1\|2928242_2928797_-	hypothetical protein	NA	NA	NA	NA
WP_023299864.1\|2928805_2929468_-	hypothetical protein	R9TR34	Vibrio_phage	1.9e-21	36.7
WP_058691500.1\|2929469_2929826_-	hypothetical protein	NA	NA	NA	NA
WP_058691501.1\|2929825_2930161_-	DUF2190 family protein	NA	NA	NA	NA
WP_032677243.1\|2930233_2932294_-\|protease	Clp protease ClpP	A0A1B0YZU0	Pseudomonas_phage	2.9e-201	57.8
WP_058691502.1\|2932283_2933804_-\|portal	phage portal protein	K7PHM5	Enterobacterial_phage	1.3e-153	55.6
WP_023299859.1\|2933812_2934028_-	hypothetical protein	NA	NA	NA	NA
WP_058691503.1\|2934024_2936145_-\|terminase	phage terminase large subunit family protein	A5LH27	Enterobacteria_phage	4.9e-305	74.8
WP_023299857.1\|2936148_2936652_-	DUF1441 family protein	K7PJY2	Enterobacterial_phage	3.1e-48	62.9
WP_058691504.1\|2936971_2937175_-	hypothetical protein	NA	NA	NA	NA
WP_080399903.1\|2937442_2938360_-	trypsin-like peptidase domain-containing protein	S5FV10	Shigella_phage	6.8e-70	68.1
WP_058691506.1\|2938459_2938651_-	hypothetical protein	A0A286SGR9	Klebsiella_phage	6.2e-18	76.4
WP_058691507.1\|2938601_2938880_-	hypothetical protein	G8C7W1	Escherichia_phage	7.9e-22	68.2
WP_058691508.1\|2939121_2939754_-	glycoside hydrolase family 19 protein	G8C7W0	Escherichia_phage	2.8e-99	85.2
WP_044489029.1\|2939750_2940047_-\|holin	phage holin family protein	G8C7V9	Escherichia_phage	5.5e-05	33.8
WP_058691509.1\|2940043_2940448_-	hypothetical protein	NA	NA	NA	NA
WP_058691510.1\|2941338_2941944_-	hypothetical protein	H9C175	Pectobacterium_phage	9.3e-76	66.2
WP_058691511.1\|2941940_2942297_-	RusA family crossover junction endodeoxyribonuclease	K7P6W0	Enterobacteria_phage	3.5e-38	58.5
WP_114078455.1\|2942289_2943990_-	DNA (cytosine-5-)-methyltransferase	A0A1B0V7P0	Salmonella_phage	2.3e-148	50.8
WP_032619479.1\|2943982_2944279_-	DUF968 domain-containing protein	Q6V7S4	Burkholderia_virus	2.6e-23	59.1
WP_032619477.1\|2944763_2945087_-	hypothetical protein	K7PGV5	Enterobacterial_phage	7.0e-30	60.8
WP_058691533.1\|2945270_2945783_-	hypothetical protein	NA	NA	NA	NA
WP_058691513.1\|2945790_2947017_-	ATP-binding protein	NA	NA	NA	NA
WP_058691514.1\|2947359_2948016_-	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	9.3e-13	26.1
WP_058691515.1\|2948033_2948774_-	DNA replication protein DnaC	S4TNF5	Salmonella_phage	3.9e-100	72.7
WP_080399904.1\|2948776_2949694_-	hypothetical protein	U5P0A0	Shigella_phage	1.4e-51	39.7
WP_058691534.1\|2949716_2950169_-	hypothetical protein	NA	NA	NA	NA
WP_032619472.1\|2950168_2950438_-	hypothetical protein	H6WRX5	Salmonella_phage	2.2e-08	38.7
WP_045897132.1\|2950510_2951002_+	helix-turn-helix domain-containing protein	A0A0R6PH50	Moraxella_phage	3.6e-17	56.2
WP_058691517.1\|2951276_2951471_+	hypothetical protein	NA	NA	NA	NA
WP_058691518.1\|2951448_2951703_-	hypothetical protein	NA	NA	NA	NA
WP_032619469.1\|2952131_2952404_+	hypothetical protein	K7P7B3	Enterobacteria_phage	2.7e-14	44.2
WP_058691519.1\|2952626_2954531_+	hypothetical protein	S4TNL0	Salmonella_phage	2.8e-25	36.4
WP_058691520.1\|2954517_2954760_+	DUF4060 family protein	M9P0E0	Enterobacteria_phage	3.2e-11	50.0
WP_032619466.1\|2954819_2955041_+	DUF4224 domain-containing protein	H9C153	Pectobacterium_phage	1.8e-08	42.9
WP_058691521.1\|2955040_2956054_+\|integrase	tyrosine-type recombinase/integrase	H9C152	Pectobacterium_phage	2.5e-134	69.0
2960721:2960737	attR	NA	NA	NA	NA

DBSCAN-SWA_7

3055198 : 3062944

Bodo_saltans_virus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003859480.1\|3055198_3055810_+	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE	A0A2H4UVM0	Bodo_saltans_virus	2.1e-14	29.3
WP_003859479.1\|3055848_3056829_-	LPS O-antigen chain length determinant protein WzzB	NA	NA	NA	NA
WP_003859478.1\|3057021_3058026_+	NAD-dependent epimerase	A0A2K9L0I7	Tupanvirus	1.1e-33	29.3
WP_003859477.1\|3058074_3059241_-	UDP-glucose 6-dehydrogenase	A0A1J0FA55	Only_Syngen_Nebraska_virus	4.1e-112	54.0
WP_003859476.1\|3059480_3060362_-	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	1.5e-103	62.4
WP_003859475.1\|3060362_3061448_-	dTDP-glucose 4,6-dehydratase	A0A291LAD7	Escherichia_phage	3.7e-99	52.6
WP_058691526.1\|3061537_3062944_-	NADP-dependent phosphogluconate dehydrogenase	M4QQM4	Ostreococcus_lucimarinus_virus	3.1e-37	28.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP042489

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP042488

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection