CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP045147	Yersinia pestis strain SCPM-O-B-6899 (231) plasmid pCD, complete sequence	0 crisprs	NA	0	0	1	0
NZ_CP045146	Yersinia pestis strain SCPM-O-B-6899 (231) plasmid pMT, complete sequence	0 crisprs	NA	0	0	1	0
NZ_CP045145	Yersinia pestis strain SCPM-O-B-6899 (231) chromosome, complete genome	7 crisprs	csa3,cas3,cas1,cas3f,cas8f,cas5f,cas7f,cas6f,DEDDh,DinG	3	10	14	1
NZ_CP045148	Yersinia pestis strain SCPM-O-B-6899 (231) plasmid pPCP, complete sequence	0 crisprs	NA	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

8910 : 67503

Enterobacteria_phage(42.86%)

protease,transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000255944.1\|8910_9933_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_002213278.1\|10596_12003_+	T3SS effector protein-tyrosine-phosphatase YopH	NA	NA	NA	NA
WP_002212907.1\|14091_14439_-	type III secretion system exported negative regulator LcrQ/YscM1	NA	NA	NA	NA
WP_002212909.1\|14663_15296_-	HrpE/YscL family type III secretion apparatus protein	NA	NA	NA	NA
WP_002361471.1\|15274_15904_-	type III secretion system sorting platform protein YscK	NA	NA	NA	NA
WP_002212912.1\|15903_16638_-	type III secretion inner membrane ring lipoprotein SctJ	NA	NA	NA	NA
WP_002212914.1\|16644_16992_-	type III secretion system inner rod subunit SctI	NA	NA	NA	NA
WP_002212915.1\|16992_17490_-	YopR family type III secretion effector	NA	NA	NA	NA
WP_002229801.1\|17486_17834_-	YscG family type III secretion protein	NA	NA	NA	NA
WP_002212916.1\|17835_18099_-	type III secretion system needle filament subunit SctF	NA	NA	NA	NA
WP_002212917.1\|18099_18300_-	EscE/YscE/SsaE family type III secretion system needle protein co-chaperone	NA	NA	NA	NA
WP_002212919.1\|18296_19556_-	type III secretion system inner membrane ring subunit SctD	NA	NA	NA	NA
WP_002212923.1\|19552_21376_-	type III secretion system outer membrane ring subunit SctC	NA	NA	NA	NA
WP_002212925.1\|21381_21795_-	type III secretion system chaperone YscB	NA	NA	NA	NA
WP_002229797.1\|22020_22119_-	type III secretion system protein YscA	NA	NA	NA	NA
WP_002212931.1\|22197_23013_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_002222527.1\|23136_23532_-	type III secretion system chaperone YscW	NA	NA	NA	NA
WP_002212936.1\|24107_25172_-	type III secretion system export apparatus switch protein YscU	NA	NA	NA	NA
WP_002212938.1\|25171_25957_-	type III secretion system export apparatus protein SctT	NA	NA	NA	NA
WP_002212945.1\|25953_26220_-	type III secretion system export apparatus subunit SctS	NA	NA	NA	NA
WP_002212947.1\|26221_26875_-	type III secretion system export apparatus protein SctR	NA	NA	NA	NA
WP_002212948.1\|26871_27795_-	YscQ/HrcQ family type III secretion apparatus protein	NA	NA	NA	NA
WP_002212950.1\|27791_29159_-	type III secretion system needle length determinant	NA	NA	NA	NA
WP_002212952.1\|29158_29623_-	type III secretion system central stalk protein YscO	NA	NA	NA	NA
WP_002212955.1\|29619_30939_-	EscN/YscN/HrcN family type III secretion system ATPase	NA	NA	NA	NA
WP_002212958.1\|31136_32018_+	type III secretion system gatekeeper subunit YopN	NA	NA	NA	NA
WP_002212965.1\|31998_32277_+	type III secretion system gatekeeper subunit TyeA	NA	NA	NA	NA
WP_002229794.1\|32263_32635_+	type III secretion chaperone SycN	NA	NA	NA	NA
WP_002212969.1\|32631_33000_+	type III secretion system protein YscX	NA	NA	NA	NA
WP_002229791.1\|32996_33341_+	type III secretion system chaperone YscY	NA	NA	NA	NA
WP_002212971.1\|33327_35442_+	type III secretion system export apparatus subunit SctV	NA	NA	NA	NA
WP_002220918.1\|35438_35879_+	type III secretion system regulator LcrR	NA	NA	NA	NA
WP_002212973.1\|35920_36208_+	type III secretion protein LcrG	NA	NA	NA	NA
WP_002212981.1\|36209_37190_+	type III secretion system protein LcrV	NA	NA	NA	NA
WP_002222758.1\|37202_37709_+	type III secretion system chaperone LcrH	NA	NA	NA	NA
WP_002212985.1\|37686_38892_+	type III secretion system translocon subunit YopB	NA	NA	NA	NA
WP_002212987.1\|38910_39831_+	type III secretion system translocon subunit YopD	NA	NA	NA	NA
WP_002229781.1\|40956_41166_+	hypothetical protein	NA	NA	NA	NA
WP_002222517.1\|41496_42789_+	T3SS effector E3 ubiquitin ligase YopM	NA	NA	NA	NA
WP_116442925.1\|43030_43276_-	hypothetical protein	NA	NA	NA	NA
WP_002393889.1\|44024_44375_-	hypothetical protein	NA	NA	NA	NA
WP_002213004.1\|45148_45547_-	type III secretion system chaperone SycT	NA	NA	NA	NA
WP_002213006.1\|45546_46515_-\|protease	T3SS effector cysteine protease YopT	NA	NA	NA	NA
WP_002213007.1\|47014_47563_+	hypothetical protein	NA	NA	NA	NA
WP_002229770.1\|48160_48790_+	hypothetical protein	NA	NA	NA	NA
WP_002220902.1\|50801_51968_+	plasmid-partitioning protein SopA	Q7Y3Y6	Yersinia_phage	3.5e-196	85.3
WP_002213354.1\|51964_52930_+	ParB/RepB/Spo0J family plasmid partition protein	Q7Y3Y7	Yersinia_phage	3.1e-89	56.6
WP_154020274.1\|53089_53326_+	hypothetical protein	NA	NA	NA	NA
WP_002224342.1\|54192_54435_+	type II toxin-antitoxin system ParD family antitoxin	NA	NA	NA	NA
WP_002213360.1\|54427_54727_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_002229754.1\|54866_55526_-	type III secretion system effector GTPase activator YopE	NA	NA	NA	NA
WP_002213403.1\|55719_56112_+	YopE transcriptional regulator YerA	NA	NA	NA	NA
WP_002220893.1\|56921_58094_+\|transposase	IS21 family transposase	U5N3F9	Enterobacteria_phage	1.6e-220	95.4
WP_002213267.1\|58868_59294_+	type III secretion system chaperone SycH	NA	NA	NA	NA
WP_086016640.1\|59441_60541_-\|transposase	IS3-like element ISYpe1 family transposase	S5WIU1	Leptospira_phage	1.4e-45	38.5
WP_002229829.1\|60640_60970_-	hypothetical protein	NA	NA	NA	NA
WP_002224338.1\|61108_61573_-	hypothetical protein	NA	NA	NA	NA
WP_002213258.1\|61591_62143_-	recombinase family protein	Q1MVP4	Enterobacteria_phage	5.9e-77	80.3
WP_002213256.1\|62306_64622_+\|transposase	Tn3 family transposase	Q1MVP5	Enterobacteria_phage	1.0e-279	51.6
WP_042469136.1\|67233_67503_-\|transposase	transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP045146

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 97793

Salmonella_phage(79.22%)

tail,terminase,integrase,transposase

attL 13544:13561|attR 26602:26619

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002214164.1\|0_1065_+	replication protein RepA	J9Q7H0	Salmonella_phage	2.4e-188	98.6
WP_002222711.1\|1633_1846_-	hypothetical protein	J9Q7S8	Salmonella_phage	6.8e-34	95.7
WP_002227818.1\|1845_2181_-	hypothetical protein	J9Q7Z5	Salmonella_phage	5.2e-52	91.0
WP_002228796.1\|2177_2357_-	hypothetical protein	J9Q6J1	Salmonella_phage	5.8e-18	86.4
WP_002228797.1\|2397_2673_-	hypothetical protein	J9Q738	Salmonella_phage	1.7e-45	95.6
WP_002222869.1\|2740_3151_-	hypothetical protein	J9Q7G9	Salmonella_phage	4.1e-75	97.8
WP_002222868.1\|3134_3506_-	DUF2591 domain-containing protein	J9Q7S7	Salmonella_phage	4.0e-61	87.8
WP_002222866.1\|3659_4490_-	hypothetical protein	J9Q7Z4	Salmonella_phage	9.3e-127	98.6
WP_002213439.1\|4493_4694_-	hypothetical protein	J9Q6J0	Salmonella_phage	1.1e-25	97.0
WP_161597819.1\|4784_5816_-	recombinase	J9Q736	Salmonella_phage	6.9e-196	99.1
WP_000920226.1\|5863_6130_-	hypothetical protein	J9Q7G8	Salmonella_phage	1.6e-40	100.0
WP_002225551.1\|6129_7074_-	exonuclease	J9Q7S6	Salmonella_phage	1.3e-180	99.0
WP_002213135.1\|8277_8709_-	hypothetical protein	J9Q6I8	Salmonella_phage	2.6e-72	98.6
WP_002215095.1\|8929_9181_+	hypothetical protein	NA	NA	NA	NA
WP_002213141.1\|9253_9817_+	DNA-binding protein	J9Q7G7	Salmonella_phage	2.2e-63	64.6
WP_002425587.1\|9846_10272_-	hypothetical protein	J9Q7S4	Salmonella_phage	7.5e-72	100.0
WP_002221186.1\|10286_13811_-	DNA polymerase III subunit alpha	J9Q7Z2	Salmonella_phage	0.0e+00	99.2
13544:13561	attL	NA	NA	NA	NA
WP_002211767.1\|13991_15227_-	AAA domain-containing protein	J9Q733	Salmonella_phage	3.0e-238	99.3
WP_002211766.1\|15323_17690_-	porphyrin biosynthesis protein	J9Q7G6	Salmonella_phage	0.0e+00	94.4
WP_002228800.1\|17799_18012_-	hypothetical protein	NA	NA	NA	NA
WP_002228802.1\|18274_18661_+	hypothetical protein	NA	NA	NA	NA
WP_002353208.1\|18655_19759_-\|integrase	site-specific integrase	A0A1P8DTG6	Proteus_phage	5.2e-24	30.9
WP_002216410.1\|20518_21031_-	F1 capsule protein	NA	NA	NA	NA
WP_002211763.1\|21111_23613_-	F1 capsule-anchoring protein	NA	NA	NA	NA
WP_002211762.1\|23637_24414_-	chaperone Caf1M	NA	NA	NA	NA
WP_002211761.1\|24741_25647_+	F1 operon transcriptional regulator Caf1R	NA	NA	NA	NA
WP_002224363.1\|26161_26467_-	hypothetical protein	J9Q7S1	Salmonella_phage	3.2e-48	97.0
WP_002224361.1\|26612_26828_-	hypothetical protein	J9Q6I3	Salmonella_phage	7.7e-33	98.6
26602:26619	attR	NA	NA	NA	NA
WP_002233024.1\|26987_28025_-	DNA ligase	J9Q7G5	Salmonella_phage	1.8e-207	99.4
WP_001297096.1\|28100_28880_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_000255944.1\|28879_29902_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_002211744.1\|30025_32035_-	ParB/RepB/Spo0J family partition protein	G8DH78	Emiliania_huxleyi_virus	7.7e-26	30.3
WP_002211745.1\|32107_32338_-	DUF905 domain-containing protein	NA	NA	NA	NA
WP_002211746.1\|33050_33557_-	antirestriction protein	A0A1I9S7Y0	Rhodococcus_phage	1.1e-08	29.5
WP_002211747.1\|33955_34735_-	hypothetical protein	NA	NA	NA	NA
WP_002215082.1\|34788_35208_-	DUF1380 domain-containing protein	NA	NA	NA	NA
WP_002211748.1\|35218_35440_-	hypothetical protein	NA	NA	NA	NA
WP_002211749.1\|35439_36117_-	DNA methylase	A0A2I7RE86	Vibrio_phage	1.6e-28	36.9
WP_002211750.1\|36617_36818_+	hypothetical protein	NA	NA	NA	NA
WP_002228775.1\|36979_38377_-	AAA family ATPase	NA	NA	NA	NA
WP_002215070.1\|38755_39727_-	ParB/RepB/Spo0J family partition protein	Q1MVJ4	Enterobacteria_phage	1.5e-112	67.3
WP_002211752.1\|39723_40929_-	ParA family protein	Q1MVJ3	Enterobacteria_phage	1.7e-206	90.5
WP_002211753.1\|41230_41458_+	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
WP_002215068.1\|41457_41784_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_002211754.1\|41983_42604_+	recombinase family protein	A0A1V0E035	Clostridioides_phage	6.5e-08	31.1
WP_002215065.1\|42669_43611_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	Q2A0A7	Sodalis_phage	1.0e-68	54.8
WP_002211756.1\|43633_43909_-	hypothetical protein	NA	NA	NA	NA
WP_002211757.1\|44647_45136_+	phospholipase D family protein	NA	NA	NA	NA
WP_002211758.1\|45213_46977_+	phospholipase D	NA	NA	NA	NA
WP_002211760.1\|49052_50075_-\|transposase	IS110-like element IS1618 family transposase	NA	NA	NA	NA
WP_002209743.1\|50543_51752_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_002224263.1\|51785_52508_-	DUF4145 domain-containing protein	NA	NA	NA	NA
WP_002224265.1\|52760_53555_+	hypothetical protein	J9Q7Z0	Salmonella_phage	3.7e-141	96.6
WP_002224267.1\|53855_54113_+	hypothetical protein	J9Q7R9	Salmonella_phage	1.3e-34	94.1
WP_000255944.1\|54514_55537_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_001297096.1\|55536_56316_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_002211769.1\|56449_57058_-\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	4.8e-64	62.2
WP_002211770.1\|57359_60248_-\|tail	phage tail protein	J9Q6E3	Salmonella_phage	4.5e-11	33.1
WP_002211771.1\|60328_60907_-	DUF4376 domain-containing protein	Q9LA61	Enterobacterial_phage	3.4e-27	38.8
WP_002214118.1\|60963_65595_-	DUF1983 domain-containing protein	J9Q713	Salmonella_phage	0.0e+00	88.6
WP_002211773.1\|65616_66204_-\|tail	tail assembly protein	J9Q7F8	Salmonella_phage	5.1e-103	92.8
WP_002211774.1\|66191_66989_-\|tail	tail protein	J9Q7R4	Salmonella_phage	1.4e-156	96.2
WP_002211775.1\|66981_67680_-\|tail	phage minor tail protein L	J9Q7Y5	Salmonella_phage	7.1e-136	99.1
WP_000440566.1\|67769_68105_-\|tail	phage tail protein	J9Q6E1	Salmonella_phage	5.7e-59	97.3
WP_002211776.1\|68146_72724_-	tape measure protein	J9Q712	Salmonella_phage	0.0e+00	90.5
WP_000952684.1\|72731_72956_-	hypothetical protein	J9Q7F7	Salmonella_phage	4.2e-34	100.0
WP_000163862.1\|73081_73399_-	hypothetical protein	J9Q7R3	Salmonella_phage	6.0e-50	98.1
WP_002211778.1\|73458_74205_-	Ig domain-containing protein	J9Q7Y4	Salmonella_phage	5.2e-129	98.8
WP_002211779.1\|74279_74663_-	hypothetical protein	J9Q6D8	Salmonella_phage	1.1e-66	98.4
WP_002211780.1\|74664_75138_-	hypothetical protein	J9Q711	Salmonella_phage	8.9e-82	99.4
WP_001027662.1\|75128_75473_-	hypothetical protein	J9Q7F6	Salmonella_phage	1.9e-57	100.0
WP_002211781.1\|75570_76404_-	hypothetical protein	J9Q7R2	Salmonella_phage	2.9e-152	99.6
WP_002211782.1\|76403_76838_-	hypothetical protein	J9Q7Y3	Salmonella_phage	3.1e-73	99.3
WP_002211783.1\|76881_77544_-	Ig domain-containing protein	J9Q6D6	Salmonella_phage	8.5e-107	97.2
WP_002211784.1\|77618_78494_-	hypothetical protein	J9Q710	Salmonella_phage	8.5e-163	99.7
WP_002231160.1\|78520_79417_-	hypothetical protein	J9Q7F4	Salmonella_phage	3.9e-147	96.3
WP_002211786.1\|79439_81014_-	hypothetical protein	J9Q7R1	Salmonella_phage	2.4e-301	99.2
WP_002211787.1\|81047_82304_-\|terminase	terminase	J9Q7Y2	Salmonella_phage	1.8e-251	100.0
WP_002211788.1\|82306_82948_-	hypothetical protein	J9Q6D4	Salmonella_phage	1.2e-108	98.1
WP_000176291.1\|83143_83410_-	hypothetical protein	J9Q757	Salmonella_phage	1.3e-42	100.0
WP_002211789.1\|83419_84310_-	hypothetical protein	J9Q7I6	Salmonella_phage	6.2e-169	99.7
WP_002211790.1\|84315_84570_-	hypothetical protein	J9Q7U0	Salmonella_phage	2.0e-40	97.6
WP_002211791.1\|84562_85201_-	ATP-binding cassette domain-containing protein	J9Q807	Salmonella_phage	4.7e-110	98.1
WP_002211792.1\|85197_85866_-	ParB N-terminal domain-containing protein	J9Q6L1	Salmonella_phage	9.5e-114	98.2
WP_002228791.1\|85865_86564_-	ParB N-terminal domain-containing protein	J9Q756	Salmonella_phage	9.6e-125	98.7
WP_002211794.1\|86628_88188_+	DEAD/DEAH box helicase	J9Q7I4	Salmonella_phage	1.1e-293	99.0
WP_002214131.1\|88190_88469_+	hypothetical protein	J9Q7T9	Salmonella_phage	4.4e-41	97.8
WP_002211796.1\|88528_88951_+	hypothetical protein	J9Q806	Salmonella_phage	4.1e-62	85.0
WP_002214134.1\|88955_89483_+	transcriptional regulator	J9Q6L0	Salmonella_phage	6.4e-81	98.0
WP_002211799.1\|89806_90457_+	hypothetical protein	J9Q754	Salmonella_phage	4.1e-114	99.5
WP_002214137.1\|90541_90769_+	hypothetical protein	NA	NA	NA	NA
WP_002211801.1\|91407_91890_-	hypothetical protein	J9Q805	Salmonella_phage	5.1e-85	94.4
WP_002211802.1\|92095_92377_-	hypothetical protein	J9Q753	Salmonella_phage	6.1e-46	93.5
WP_002213759.1\|92576_93035_-\|transposase	IS200/IS605-like element IS1541A family transposase	D9CGB6	Hyperthermophilic_Archaeal_Virus_2	5.0e-13	35.3
WP_002214145.1\|93243_93813_-	hypothetical protein	J9Q7Z7	Salmonella_phage	5.8e-104	100.0
WP_002213303.1\|93825_94572_-	hypothetical protein	J9Q6J5	Salmonella_phage	4.1e-134	96.4
WP_038918515.1\|94561_94921_-	hypothetical protein	J9Q741	Salmonella_phage	5.2e-58	100.0
WP_002213300.1\|96707_97793_-	exonuclease	J9Q7S9	Salmonella_phage	7.7e-206	98.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP045145

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP045145_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045145_1

542715-543115

Orphan

Consensus_repeat	Method
AGGATAGGGCGCGAGGGGAATGACTGTCCACGACACTTTTCATAAAAGAAAGCGGCTTACCG	PILER-CR

3 spacers

The CRISPR arrays of NZ_CP045145_1

>merge|NZ_CP045145|1|542715-543115|PILER-CR
AGGATAGGGCGTGAGAGGAATGACTGTCCACGACACTTTTCATAAAAGAAAGCGGCTTACCGGTCAACGCCACTCATTCCACAAAATCCCGCTTCGGCGGGTTTTTGCTTTGGAGGATAGGGCGTGAGGGGAATGACTGTCCACGACACTTTTCATAAAAGAAAGCGGCTTACCGGTCAACGCCACTCATTCCACAAAATCCCGCTTCGGCGGGTTTTTGCTTTGCAGGATAGGGCGCGAGGGGAATGACTGTCCACGACACTTTTTATAAAAGAAAGCGGCTTACCGGTCAACGCCACTCATGCCACAAAATCCCGCTTCGGCGGGTTTTTGCTTTGCAGGATAGGGCGCGAGGGGAATGACTGTCCACGACACTTTTTATAAAAGAAAGCGGCTTACCG

>NZ_CP045145|1|1|542715-543115|PILER-CR
AGGATAGGGCGTGAGAGGAATGACTGTCCACGACACTTTTCATAAAAGAAAGCGGCTTACCG	GTCAACGCCACTCATTCCACAAAATCCCGCTTCGGCGGGTTTTTGCTTTGG
AGGATAGGGCGTGAGGGGAATGACTGTCCACGACACTTTTCATAAAAGAAAGCGGCTTACCG	GTCAACGCCACTCATTCCACAAAATCCCGCTTCGGCGGGTTTTTGCTTTGC
AGGATAGGGCGCGAGGGGAATGACTGTCCACGACACTTTTTATAAAAGAAAGCGGCTTACCG	GTCAACGCCACTCATGCCACAAAATCCCGCTTCGGCGGGTTTTTGCTTTGC
AGGATAGGGCGCGAGGGGAATGACTGTCCACGACACTTTTTATAAAAGAAAGCGGCTTACCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045145.1\|WP_002210149.1\|541378_542278_+\|16S-rRNA-(cytidine(1402)-2'-O)-methyltransferase	unknown	unknown	gnl\|CDD\|184956
NZ_CP045145.1\|WP_152329034.1\|539342_541316_-\|penicillin-binding-protein-activator	unknown	unknown	gnl\|CDD\|225649
NZ_CP045145.1\|WP_002210150.1\|543214_543919_-\|pirin-family-protein	unknown	unknown	gnl\|CDD\|224655
NZ_CP045145.1\|WP_002210151.1\|544180_545074_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176122
NZ_CP045145.1\|WP_002209028.1\|548015_549002_+\|hydrolase	unknown	unknown	gnl\|CDD\|223489
NZ_CP045145.1\|WP_002210145.1\|537458_538034_-\|divisome-associated-lipoprotein-YraP	unknown	unknown	gnl\|CDD\|182907
NZ_CP045145.1\|WP_001297096.1\|546155_546935_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|181681
NZ_CP045145.1\|WP_002210143.1\|535876_536530_+\|isoprenoid-biosynthesis-glyoxalase-ElbB	unknown	unknown	gnl\|CDD\|236980
NZ_CP045145.1\|WP_002209034.1\|555402_556035_-\|two-component-system-response-regulator	unknown	unknown	gnl\|CDD\|185267
NZ_CP045145.1\|WP_002210142.1\|533298_535635_+\|aerobic-respiration-two-component-sensor-histidine-kinase-ArcB	unknown	unknown	gnl\|CDD\|236842
NZ_CP045145.1\|WP_002228691.1\|526831_531289_-\|glutamate-synthase-large-subunit	unknown	unknown	gnl\|CDD\|236968
NZ_CP045145.1\|WP_002209030.1\|550727_551039_-\|DUF485-domain-containing-protein	unknown	unknown	gnl\|CDD\|225704
NZ_CP045145.1\|WP_002210147.1\|538905_539259_-\|YraN-family-protein	unknown	unknown	gnl\|CDD\|237119
NZ_CP045145.1\|WP_002209029.1\|549075_550731_-\|cation/acetate-symporter-ActP	unknown	unknown	gnl\|CDD\|236495
NZ_CP045145.1\|WP_002210144.1\|536526_537252_+\|monofunctional-biosynthetic-peptidoglycan-transglycosylase	unknown	unknown	gnl\|CDD\|234603
NZ_CP045145.1\|WP_002209033.1\|553908_555225_+\|glutamate/aspartate:proton-symporter-GltP	unknown	unknown	gnl\|CDD\|183075
NZ_CP045145.1\|WP_000255944.1\|546934_547957_-\|IS21-like-element-IS100-family-transposase	unknown	unknown	gnl\|CDD\|226950
NZ_CP045145.1\|WP_002210140.1\|532111_533035_+\|TIGR01212-family-radical-SAM-protein	unknown	unknown	gnl\|CDD\|224163
NZ_CP045145.1\|WP_002209031.1\|551095_553054_-\|acetate--CoA-ligase	unknown	unknown	gnl\|CDD\|234677
NZ_CP045145.1\|WP_002210146.1\|538044_538635_-\|DnaA-initiator-associating-protein-DiaA	unknown	unknown	gnl\|CDD\|182811

Protein	Function_ID	Function_description	E-value
NZ_CP045145.1\|WP_002210149.1\|541378_542278_+\|16S-rRNA-(cytidine(1402)-2'-O)-methyltransferase	gnl\|CDD\|184956	PRK14994, PRK14994, SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional.	0
NZ_CP045145.1\|WP_152329034.1\|539342_541316_-\|penicillin-binding-protein-activator	gnl\|CDD\|225649	COG3107, LppC, Putative lipoprotein [General function prediction only].	0
NZ_CP045145.1\|WP_002210150.1\|543214_543919_-\|pirin-family-protein	gnl\|CDD\|224655	COG1741, COG1741, Pirin-related protein [General function prediction only].	1.10509e-65
NZ_CP045145.1\|WP_002210151.1\|544180_545074_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176122	cd08431, PBP2_HupR, The C-terminal substrate binding domain of LysR-type transcriptional regulator, HupR, which regulates expression of the heme uptake receptor HupA; contains the type 2 periplasmic binding fold. HupR, a member of the LysR family, activates hupA transcription under low-iron conditions in the presence of hemin. The expression of many iron-uptake genes, such as hupA, is regulated at the transcriptional level by iron and an iron-binding repressor protein called Fur (ferric uptake regulation). Under iron-abundant conditions with heme, the active Fur repressor protein represses transcription of the iron-uptake gene hupA, and prevents transcriptional activation via HupR. Under low-iron conditions with heme, the Fur repressor is inactive and transcription of the hupA is allowed. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	7.28073e-52
NZ_CP045145.1\|WP_002209028.1\|548015_549002_+\|hydrolase	gnl\|CDD\|223489	COG0412, COG0412, Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism].	1.04062e-12
NZ_CP045145.1\|WP_002210145.1\|537458_538034_-\|divisome-associated-lipoprotein-YraP	gnl\|CDD\|182907	PRK11023, PRK11023, divisome-associated lipoprotein YraP.	1.95051e-112
NZ_CP045145.1\|WP_001297096.1\|546155_546935_-\|AAA-family-ATPase	gnl\|CDD\|181681	PRK09183, PRK09183, transposase/IS protein; Provisional.	5.26232e-178
NZ_CP045145.1\|WP_002210143.1\|535876_536530_+\|isoprenoid-biosynthesis-glyoxalase-ElbB	gnl\|CDD\|236980	PRK11780, PRK11780, isoprenoid biosynthesis glyoxalase ElbB.	6.53077e-145
NZ_CP045145.1\|WP_002209034.1\|555402_556035_-\|two-component-system-response-regulator	gnl\|CDD\|185267	PRK15369, PRK15369, two component system response regulator.	9.65251e-141
NZ_CP045145.1\|WP_002210142.1\|533298_535635_+\|aerobic-respiration-two-component-sensor-histidine-kinase-ArcB	gnl\|CDD\|236842	PRK11091, PRK11091, aerobic respiration control sensor protein ArcB; Provisional.	0
NZ_CP045145.1\|WP_002228691.1\|526831_531289_-\|glutamate-synthase-large-subunit	gnl\|CDD\|236968	PRK11750, gltB, glutamate synthase subunit alpha; Provisional.	0
NZ_CP045145.1\|WP_002209030.1\|550727_551039_-\|DUF485-domain-containing-protein	gnl\|CDD\|225704	COG3162, COG3162, Predicted membrane protein [Function unknown].	1.68243e-49
NZ_CP045145.1\|WP_002210147.1\|538905_539259_-\|YraN-family-protein	gnl\|CDD\|237119	PRK12497, PRK12497, YraN family protein.	4.17484e-53
NZ_CP045145.1\|WP_002209029.1\|549075_550731_-\|cation/acetate-symporter-ActP	gnl\|CDD\|236495	PRK09395, actP, cation/acetate symporter ActP.	0
NZ_CP045145.1\|WP_002210144.1\|536526_537252_+\|monofunctional-biosynthetic-peptidoglycan-transglycosylase	gnl\|CDD\|234603	PRK00056, mtgA, monofunctional biosynthetic peptidoglycan transglycosylase; Provisional.	1.31484e-142
NZ_CP045145.1\|WP_002209033.1\|553908_555225_+\|glutamate/aspartate:proton-symporter-GltP	gnl\|CDD\|183075	PRK11283, gltP, glutamate/aspartate:proton symporter; Provisional.	0
NZ_CP045145.1\|WP_000255944.1\|546934_547957_-\|IS21-like-element-IS100-family-transposase	gnl\|CDD\|226950	COG4584, COG4584, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	3.49492e-79
NZ_CP045145.1\|WP_002210140.1\|532111_533035_+\|TIGR01212-family-radical-SAM-protein	gnl\|CDD\|224163	COG1242, COG1242, Predicted Fe-S oxidoreductase [General function prediction only].	6.23198e-179
NZ_CP045145.1\|WP_002209031.1\|551095_553054_-\|acetate--CoA-ligase	gnl\|CDD\|234677	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional.	0
NZ_CP045145.1\|WP_002210146.1\|538044_538635_-\|DnaA-initiator-associating-protein-DiaA	gnl\|CDD\|182811	PRK10886, PRK10886, DnaA initiator-associating protein DiaA; Provisional.	2.90112e-140

>NZ_CP045145.1|WP_002210149.1|541378_542278_+|16S-rRNA-(cytidine(1402)-2'-O)-methyltransferase
MNQHDRAVISASTLYVVPTPIGNLGDITHRALEVLKGVDLIAAEDTRHTGLLLQHFAINARLFALHDHNEQQKADQLLAKLQEGQSIALVSDAGTPLINDPGYHLVRRCREAGIRVVPLPGACAAITALSAAGLASDRFCYEGFLPAKTKGRKDTLQALIEEPRTLIFYESTHRLLESLQDMVTVLGPQRYVVLARELTKTWESIHGAPVGELLAWVKEEETRRRGEMVLIVEGHKVQSDDALPADALRTLALLQKELPLKKAAALAAEIHGVKKNALYKYALEQQQGDVETEEDDIQQ
>NZ_CP045145.1|WP_152329034.1|539342_541316_-|penicillin-binding-protein-activator
MLSSTFVRSKAGLVPVILAALILAACTGDAPQTPPPVNIQDEASANSDYYLQQLQQSSDDNKADWQLLAIRALLREAKVPQAAEQLSTLPANLSDTQRQEQQLLAAELLIAQKNTPAAADILAKLEATQLSANQKVRYYQAQIAANQDKATLPLIRAFIAQEPLLTDKAHQDNIDGTWQSLSQLTPQELNTMVINADENVLQGWLDLLRVYQDNKQDPELLKAGIKDWQTRYPQNPAAKNLPTALTQISNFSQASTAKIALLLPLSGPAQVFADAIQQGFTAAQNGSAVTASVPVTPNVTESSPTDTAAVVSDDTPATLPTTMPPPVVTNAQVKIYDTNTQPLAALLAQAQQDGATLVVGPLLKPEVEQLSATPSTLNILALNQPEASNNSPNICYFALSPEDEARDAAHHLWEQQKRMPLLLVPRGALGERIAKAFADEWQKQGGQTVLQQNFGSTTELKQSINSGAGIRLTGTPVSVSNVAAAPASVTIAGLTIPAPPIDAPVVSTSSSGNIDAVYIIATPSELTLIKPMIDMATSSRSKPALFASSRSYQAGAGPDYRLEMEGIQFSDIPLMAGSNPALLQQASAKYANDYSLVRLYAMGIDAWALANHFSEMRQIPGFQVKGVTGDLTASSDCVITRKLPWLQYRQGMVVPLA
>NZ_CP045145.1|WP_002210147.1|538905_539259_-|YraN-family-protein
MSQRDTGAHYENLARRHLERAGLVFQAANVAFRGGEIDLIMRDGDAWVFVEVRFRRNDLFGGAAASITPRKQQRLHLAAAVWLAQRGASFATTSCRFDVVAITGNQLEWLPNAFNTD
>NZ_CP045145.1|WP_002210146.1|538044_538635_-|DnaA-initiator-associating-protein-DiaA
MLERIKGCFTESIQTQIAAAEALPDAISCAAMALVQSLLNGNKILCCGNGTSAANAQHFAASMINRFETERPSLPAIALNADNVVLTAITNDRLHDEVYAKQVRALGQAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVALTGYDGGELAGLLGQLDVEIRIPSHRGARVQELHMLTVNCLCDLIDNTLFPHQND
>NZ_CP045145.1|WP_002210145.1|537458_538034_-|divisome-associated-lipoprotein-YraP
MKVGYIFAMLFSTLLLQGCVGAVVVGSAAVATKTATDPRTIGTQVDDGTLEARVVNALSKDKEIKSQTRFVVTAYQGKVLLTGQTPSAELSNRAKQIASGVDGVTEVYNEMRLGKPVDLSTASMDTWITTKVRSQLLTSDSVKSSNVKVTTENGEVFLLGLVTQQEAQSAAQIASKVSGVKHVTTAFTIVK
>NZ_CP045145.1|WP_002210144.1|536526_537252_+|monofunctional-biosynthetic-peptidoglycan-transglycosylase
MISVRRGFSQLWYWGKRGVIGIIALWMAGILIFAFLPVPFSMVMIERQLGAWLTGDFAYVAHSDWVPMDEISPYMALAVMAAEDQKFPDHWGFDVGAIESALSHNQRNQKRIRGASTLSQQTAKNVFLWDGRSWVRKGLEVGLTAGIELIWTKRRILTVYLNIAEFGNGIFGVEAAARHFFNKPASKLSASEAALLAAVLPNPLRFKVNAPSGYVISRQQWILRQMHQLGGKTFLQENTLD
>NZ_CP045145.1|WP_002210143.1|535876_536530_+|isoprenoid-biosynthesis-glyoxalase-ElbB
MKTVGVVLSGCGVLDGAEIHESVLTMLALDRAGAEVLFFAPDKPQLHVINHITGEIVAEERNVLVESARIARGLITPLSAADPEVLDALIVPGGFGAAKNLCDFAIKGGECSVEPDLYKLIQLMHKSGKPIGLMCISPVMLPKLLGKPIRLTIGNDPDTIDAIEIMGGEHVICPADDVVIDLENKVVTTPAYMLAGSISEAAKGIDKLVTKVLDLTE
>NZ_CP045145.1|WP_002210142.1|533298_535635_+|aerobic-respiration-two-component-sensor-histidine-kinase-ArcB
MKQIRVLAQYYVDLMVKLGLVRFSLLLASALVLLAMVVQMAVTFVLRGSVETLDLVRSIFFGLLITPWAVYFLSVVVEQLEESRQRLSRLVDKLEVMRHRDLELNKQLTENITQLNQEIVEREKAEKAHLQVVDKLKEEMGHREQAQIELGQQSALLRSFLDASPDLVYYRNEDNEFSGCNRAMELLTGKSEKQLVGLTPKDVYAPDIAEKVMETDEKVFRHNVSLTYEQWLVYPDGRKACFELRKVPFYDRVGKRHGLMGFGRDITERKRYQDALENASRDKTTFISTISHELRTPLNGIVGLSRILLDTELDAEQLKYLKTIHVSAITLGNIFNDIIEMDKLERRKVQLDNQPVDFTGFMADLENLSGLLVQPKGLKFIMEPQLPLPEKVIADGTRLRQILWNLIGNAVKFTQQGKIVVRVRREGNDRLIFEVEDSGMGIPEDEQDKIFAMYYQVKDRNGGRPATGTGIGLAVSKRLAQSMGGDITVKSTQGVGSCFTLTIKAPAVQEASNAPSGDDMPLPALHVLLVEDIELNVIVARSVLEKLGNSVDVAMNGHDALAMFNPEDFDLVLLDIQLPDMSGLDIARQIRAEYGKQSLPPLVALTANVLKDKKEYLDAGMDDVLSKPLSVPALTAMIKQFWDSKPSSAVQKQEHKVMQTHESLLDTTMLEQYIDLVGPQLIHQSLEMFEQMMPGYLAVLDSNMTARDQKGITEEAHKIKGAAGSVGLRHIQQLAQQIQTPTLPAWWDNVQDWVDELKLEWRNDVQVLREWAAEVEKK
>NZ_CP045145.1|WP_002210140.1|532111_533035_+|TIGR01212-family-radical-SAM-protein
MQLQQLVNMFGADLQRRYGEKIHKLTLHGGFSCPNRDGTLGRGGCTFCQVASFADEQMQQQSITQQLAIQAKKANRANRYLAYFQAYTSTYAEVNALAAMYQQALCEADIVGLCVGTRPDCVPDAVLDLLSSYQQQGYEVWLELGLQTANDKTLKRINRGHDFACYQQTARRARARGLKVCCHLIVGLPGEDRAQGRETLEKVVTTGVDGIKLHPLHIVEGSTMAKAWRAGRLTALALEDYVLTAGEMIRHTPAEVVYHRISASARRPTLLAPLWCENRWTGMNELNNYLLQHGVQGTAIGDAYCYR
>NZ_CP045145.1|WP_002228691.1|526831_531289_-|glutamate-synthase-large-subunit
MLYDQSQERDNCGFGLIAHIEGEPSHKVVRTAIHALARMQHRGAILADGKTGDGCGLLLQKPDHFFRMVAEERGWRLAKNYAVGMMFLSQDEELAKASRRIVEEELQNETLSIVGWREVPTNPDVLGEIALSSLPRIEQIFVNAPAGWRSRDMERRLFVARRRIEKRISDKDFYACSFSNLVTIYKGLCMPADLPRFYLDLADLRLESAICLFHQRFSTNTVPRWPLAQPFRYLAHNGEINTIAGNRQWAKARAYKFKTPLIPDLQDAAPFVNETGSDSSSLDNMLELFLSGGMDLIRAMRLLVPPAWQNNPDMDTDLRAFFDFNSMHMEPWDGPAGIVMSDGRYAACNLDRNGLRPARYVITKDKLITCASEVGIWDYQPDEVVEKGRVGPGELMVIDTRSGKILHSAETDNDLKSRHPYKEWMEKNVKRLVPFEDLPEEQVGSRQLDDSQLETYQKQFGYSNEELDQIIRVLGENGQEATGSMGDDTPFAVLSSGPRIIYDYFRQQFAQVTNPPIDPLREAHVMSLATSIGREMNVFCEAEGQAHRLSFKSPILLYSDFQQLTTLEGEHYRADRLDLTFNPAENDLEQAVLSLCDEAERKVRDGAVMLVLSDRAIAPNRLPVPAPMAVGAIQTRLVDKSLRCDANIIVETASARDPHHFAVLLGFGATAIYPYLAYESLAKLVDSQAIDKKYRDVMLNYRNGINKGLYKIMSKMGISTVASYRCAKLFEAVGLHRDLSDLCFQGVVSRIGGASFSDFQQDLQNLSKRAWLKRKPLDQGGLLKFVHNGEYHAYNPDVVSTLQKAVHSGEYSDYQAYAKLVNERPIATLRDLLAIKPQGTPIPVDQVEPAESLFKRFDTAAMSIGALSPEAHESLAIAMNSLGGFSNSGEGGEDPARYGTNKVSRIKQVASGRFGVTPAYLVNADVIQIKVAQGAKPGEGGQLPGDKVTPYIAKLRYSVPGVTLISPPPHHDIYSIEDLAQLIFDLKQVNPKAMISVKLVSEPGVGTIATGVAKAYADLITIAGYDGGTGASPLSSVKYAGCPWELGLVETQQALVANGLRHKIRLQVDGGLKTGVDIVKAAILGAESFGFGTGPMVALGCKYLRICHLNNCATGVATQDEKLRRDHYHGLPERVVNYFHFIARETREIMAELGVSQLVDLIGRTDMLLELDGISAKQNKLDLSPMLKTATPHPGKALYCTESNPPFDKGLLNKELLSQAEPYIEAKQSKTFYFDIRNTDRSVGAALSGAIATKHGDQGLATDPIKAYFSGTAGQSFGVWNAGGVELMLTGDANDYVGKGMAGGRIAVRPPVGSNFRSHEASIIGNTCLYGATGGKLFAAGRAGERFAVRNSGAITVVEGIGDNGCEYMTGGIVCVLGRTGINFGAGMTGGFAYVLDEDGEFRKRVNPELVEVLDVEQLAIHEEHLRGLITEHVQLTGSSRGEEILANWPEWVTKFALVKPKSSDVKALLGHRSRSAAELRVQAQ
>NZ_CP045145.1|WP_002210150.1|543214_543919_-|pirin-family-protein
MITCRTAEQCGQADFGWLQARYTFSFGHYFDPTLLGYASLRVLNQEVLAPGAAFQPRTYPQVDILNLILQGEAEYRDSLGNHVHAKTGDALLFSPQQGVSYSEHNLSANKSLTRIQLWLNACPERESAPTQHQRLSTRPVQLLASPAGEQGSLQLRQQMWIHHLALAAGEQQKMPLHGHRAYLQSIHGTVDATGPQTGTSQRLTCGDGAFVEEEQHLVIKAITPLRALLIDLPV
>NZ_CP045145.1|WP_002210151.1|544180_545074_+|LysR-family-transcriptional-regulator
MARDRALTLEALRVMDAIDRRGSFAAAADELGRVPSALSYTMQKLEEELDVVLFDRSGHRTKFTNVGRMLLERGRVLLEAADKLTTDAEALARGWETHITIVSEALSPAWKLFPLIDKLALKANTQVSILTEVLAGAWERLEQGRADIVIAPDMHFRASSEINSRKLYKVTSVYVASPDHPIHQEPEPLSELTRVKYRGIAVADTARERPVITVQLLDKQQRLTVSTIEDKRRALLAGLGVATMPYEMVEKDIAAGRLRVIGPEYSREADIIMAWRRDSMGEAKSWCLREIPKLLGK
>NZ_CP045145.1|WP_001297096.1|546155_546935_-|AAA-family-ATPase
MMELQHQRLMALAGQLQLESLISAAPALSQQAVDQEWSYMDFLEHLLHEEKLARHQRKQAMYTRMAAFPAVKTFEEYDFTFATGAPQKQLQSLRSLSFIERNENIVLLGPSGVGKTHLAIAMGYEAVRAGIKVRFTTAADLLLQLSTAQRQGRYKTTLQRGVMAPRLLIIDEIGYLPFSQEEAKLFFQVIAKRYEKSAMILTSNLPFGQWDQTFAGDAALTSAMLDRILHHSHVVQIKGESYRLRQKRKAGVIAEANPE
>NZ_CP045145.1|WP_000255944.1|546934_547957_-|IS21-like-element-IS100-family-transposase
MVTFETVMEIKILHKQGMSSRAIARELGISRNTVKRYLQAKSEPPKYTPRPAVASLLDEYRDYIRQRIADAHPYKIPATVIAREIRDQGYRGGMTILRAFIRSLSVPQEQEPAVRFETEPGRQMQVDWGTMRNGRSPLHVFVAVLGYSRMLYIEFTDNMRYDTLETCHRNAFRFFGGVPREVLYDNMKTVVLQRDAYQTGQHRFHPSLWQFGKEMGFSPRLCRPFRAQTKGKVERMVQYTRNSFYIPLMTRLRPMGITVDVETANRHGLRWLHDVANQRKHETIQARPCDRWLEEQQSMLALPPEKKEYDVHLDENLVNFDKHPLHHPLSIYDSFCRGVA
>NZ_CP045145.1|WP_002209028.1|548015_549002_+|hydrolase
MDHYCTVRYRSDTRKILRQALLTPNSTITFSAEKIEQQDRGSYIAEKIALNITDESRVLGLLLTPKTKGPHPAIVLLHDHGSKFDIGKEKMIRPWGDSAKLASAQAWSDKFFSGKFVGDELAKRGYVVFSIDSIGWGDRGPMSYERQQALASNFFNLGRSLAGTMAYEDMRTVDFMTTLPSVDRKRIGVLGFSMGAYRAWQLAALSDQVAATAAISWFGNYKGLMTPDNNVLRGQSSFYMLHPGIANKLDFPDIASLAAPRPMLLFNGGKDKLFPAQAVEQAYDKVHAIWRSQNAEPRLVTRSWPTLGHVFYQEQQDVVFLWLDRWLK
>NZ_CP045145.1|WP_002209029.1|549075_550731_-|cation/acetate-symporter-ActP
MKIRHWSALSLFVLPALAQAEALTGEVHRQPLNIQAIVMFLLFVGGTLYITYWASKRTRSRQDYYTAGGRITGFQNGLAIAGDYMSAASFLGISALVYASGYDGLIYSIGFLIGWPIILFLIAERLRNLGRYTFADVASYRLQQRPIRTLSACGSLVVVALYLIAQMVGAGKLIQLLFGLNYHVAVVLVGILMVLYVLFGGMLATTWVQIIKAVMLLSGATFMAIMVMKSVNFNFNTLFSEAVKVHPKGLSIMSPGGLVSDPISALSLGLALMFGTAGLPHILMRFFTVSDAKEARKSVFYATGFIGYFYILTFIIGFGAILLVGPNQTFKDAAGALLGGNNMAAVHLANAVGGSFFLGFISAVAFATILAVVAGLTLAGASAVSHDLYASVIKKGKANERDELRVSKITVIILGIVAIGLGILFENQNIAFMVGLAFSIAASCNFPIIIISMYWDKLTTRGAMIGGWLGLSTAVILMILGPTIWVTILGHEKPIYPYEYPALFSMIAAFVGTWFFSITDNSETGKQERLLFKSQFVRSQTGLGASKGGAH
>NZ_CP045145.1|WP_002209030.1|550727_551039_-|DUF485-domain-containing-protein
MNDSIYQEIEDNPRFQELVKKRSRFAWLLSLITLTMYVAFIFLIAFEPQWLGTPIYTGSSVTRGIPVGVGLIVTSFILTGIYVIRANGEFDRLTAEIIREVKQ
>NZ_CP045145.1|WP_002209031.1|551095_553054_-|acetate--CoA-ligase
MSQIHKHPIPAAIAEHALITPEKYQHYYQQSVQNPDEFWGEQGKIIDWIKPYKTVKNTSFDPGHVSIRWFEDGTLNLAANCLDRHLAERGDQTAIIWEGDDPNQSKTVTYKQLHHDVCQFANVLKSLGVKKGDVVAIYMPMVPEAAVAMLACARIGAVHSVIFGGFSPDAVAGRIIDSHSKLVITADEGIRAGRAIPLKKNVDEALKNPAITSIKNVVVFQRTGNASYWEDGRDVWWHDLIKEASADCPPEEMNAEDPLFILYTSGSTGKPKGVVHTTGGYLVYAALTFKYVFDYHPGDIYWCTADVGWVTGHSYLLYGPLACGAITLMFEGVPNYPGVNRLSQVVDKHKVNILYTAPTAIRALMAEGDKAIEGTKRDSLRIMGSVGEPINPEAWEWYYNKIGNSKCPIVDTWWQTETGGFMITPLPGATELKAGSATRPFFGVQPALVDNLGNPQEGVAEGNLVITDSWPGQARTLFGDHERFEQTYFSTFKGMYFSGDGARRDEDGYYWITGRVDDVLNVSGHRLGTAEIESALVAHPKIAEAAVVGVPHNIKGQAIYAYITLNHGEEPTPELYTEVRNWVRKEIGPLATPDILHWTDSLPKTRSGKIMRRILRKIATGDTSNLGDTSTLADPSVVEKLLEEKQSMQTPS
>NZ_CP045145.1|WP_002209033.1|553908_555225_+|glutamate/aspartate:proton-symporter-GltP
MKSIKISLAWQILIALVLGILVGAVLHNQIESREWLVSNILSPAGDIFIRLIKMIVVPIVISTLIVGIAGVGDAKKLGRIGLKTIIYFEVITTIAIIIGITLANVFQPGVGIDMSALTVVDISQYEKTTEQVQSGSHSLVSTILSLIPANVFASMAKGDMLPIIFFSVLFGLGLSSLPKETKEPLLNVFKAVSESMFKVTHMIMRYAPIGVFGLISVTVANFGFASLIPLAKLVILVYAAILFFALVILGTVARLCKLRIWILIRILKDELILAYSTASSETVLPRIIEKMEAYGAPKAITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGIELSIGQEIILVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGNALAVLVIAKWENQFDDKKAKAYEKTLFAVEQTPANQS
>NZ_CP045145.1|WP_002209034.1|555402_556035_-|two-component-system-response-regulator
MNTKLLIVDDHELIIHGIKNMLAAYPRYLIVGQADNGLEVYNLCRQTEPDMVILDLGLPGMDGLDVIIQLLRRWPALKILTLTARNEEHYASRTFNSGALGYVLKKSPQQILMAAIQTVAIGKRYIDPALDASMVIKLTQGSDNTPPVLTPRERQILKLITEGSCNRVIAAQLSISQKTVETHRLNMMKKLDVHKVAELIHWSYRLGLNV

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Crispr_ID: NZ_CP045145_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045145_2

1267822-1268091

Orphan

I-F

Consensus_repeat	Method
GTTCACTGCCGCACAGGCAGCTTAGAAA	PILER-CR
GTTCACTGCCGCACAGGCAGCTTAGAAA	CRISPRCasFinder
GTTCACTGCCGCACAGGCAGCTTAGAAA	CRT

4 spacers

The CRISPR arrays of NZ_CP045145_2

>merge|NZ_CP045145|2|1267822-1268091|PILER-CR,CRISPRCasFinder,CRT
GTTCACTGCCGCACAGGCAGCTTAGAAACTGATACAATCATCCTATTTGTCCTATCCAGAAGTTCACTGCCGCACAGGCAGCTTAGAAAGACAAGAACCGAATCTTTCGCCGTGCCGTAAAGTTCACTGCCGCACAGGCAGCTTAGAAACCGAAATCATCAGATGTAATTAAGATTTTTGCTGTTCACTGCCGCACAGGCAGCTTAGAAAAGACTGATGCAAGATGGCGGTATGCGTACAGAGTTCACTGCCGCACAGGCAGCTTATAGA

>NZ_CP045145|2|2|1267822-1268031|PILER-CR
GTTCACTGCCGCACAGGCAGCTTAGAAA	CTGATACAATCATCCTATTTGTCCTATCCAGAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	GACAAGAACCGAATCTTTCGCCGTGCCGTAAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	CCGAAATCATCAGATGTAATTAAGATTTTTGCT
GTTCACTGCCGCACAGGCAGCTTAGAAA

>NZ_CP045145|2|1|1267822-1268091|CRISPRCasFinder
GTTCACTGCCGCACAGGCAGCTTAGAAA	CTGATACAATCATCCTATTTGTCCTATCCAGAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	GACAAGAACCGAATCTTTCGCCGTGCCGTAAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	CCGAAATCATCAGATGTAATTAAGATTTTTGCT
GTTCACTGCCGCACAGGCAGCTTAGAAA	AGACTGATGCAAGATGGCGGTATGCGTACAGA
GTTCACTGCCGCACAGGCAGCTTATAGA

>NZ_CP045145|2|1|1267822-1268091|CRT
GTTCACTGCCGCACAGGCAGCTTAGAAA	CTGATACAATCATCCTATTTGTCCTATCCAGAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	GACAAGAACCGAATCTTTCGCCGTGCCGTAAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	CCGAAATCATCAGATGTAATTAAGATTTTTGCT
GTTCACTGCCGCACAGGCAGCTTAGAAA	AGACTGATGCAAGATGGCGGTATGCGTACAGA
GTTCACTGCCGCACAGGCAGCTTATAGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045145.1\|WP_002210296.1\|1268094_1268949_-\|MurR/RpiR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224651
NZ_CP045145.1\|WP_002359655.1\|1270863_1272789_+\|3D-(3,5/4)-trihydroxycyclohexane-1,2-dione-acylhydrolase-(decyclizing)	unknown	unknown	gnl\|CDD\|226471
NZ_CP045145.1\|WP_002213775.1\|1259953_1260412_+\|IS200/IS605-like-element-IS1541B-family-transposase	unknown	unknown	gnl\|CDD\|224854
NZ_CP045145.1\|WP_002210304.1\|1278947_1280918_+\|5-dehydro-2-deoxygluconokinase	unknown	unknown	gnl\|CDD\|378281
NZ_CP045145.1\|WP_002216002.1\|1255683_1256265_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045145.1\|WP_002223316.1\|1266912_1267461_-\|DUF1440-domain-containing-protein	unknown	unknown	gnl\|CDD\|226008
NZ_CP045145.1\|WP_002209746.1\|1255014_1255416_-\|DUF1240-domain-containing-protein	unknown	unknown	gnl\|CDD\|336520
NZ_CP045145.1\|WP_002210297.1\|1269302_1270829_+\|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|143404
NZ_CP045145.1\|WP_002210303.1\|1277782_1278916_+\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NZ_CP045145.1\|WP_002210306.1\|1282000_1282816_+\|5-deoxy-glucuronate-isomerase	unknown	unknown	gnl\|CDD\|226241
NZ_CP045145.1\|WP_002209745.1\|1256937_1257183_+\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|372675
NZ_CP045145.1\|WP_002209749.1\|1253796_1254369_+\|Hcp-family-type-VI-secretion-system-effector	unknown	unknown	gnl\|CDD\|213799
NZ_CP045145.1\|WP_002223323.1\|1275171_1276719_+\|sugar-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224053
NZ_CP045145.1\|WP_002210302.1\|1276730_1277759_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224093
NZ_CP045145.1\|WP_002209748.1\|1254380_1254782_-\|DUF1240-domain-containing-protein	unknown	unknown	gnl\|CDD\|336520
NZ_CP045145.1\|WP_002210300.1\|1274193_1275123_+\|sugar-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380623
NZ_CP045145.1\|WP_138921619.1\|1257395_1259708_-\|penicillin-binding-protein-1C	unknown	unknown	gnl\|CDD\|273954
NZ_CP045145.1\|WP_002227852.1\|1253521_1253773_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045145.1\|WP_002210294.1\|1260527_1266506_-\|alpha-2-macroglobulin-family-protein	unknown	unknown	gnl\|CDD\|225248
NZ_CP045145.1\|WP_002227877.1\|1281070_1281991_+\|myo-inosose-2-dehydratase	unknown	unknown	gnl\|CDD\|275172

Protein	Function_ID	Function_description	E-value
NZ_CP045145.1\|WP_002210296.1\|1268094_1268949_-\|MurR/RpiR-family-transcriptional-regulator	gnl\|CDD\|224651	COG1737, RpiR, Transcriptional regulators [Transcription].	1.17523e-68
NZ_CP045145.1\|WP_002359655.1\|1270863_1272789_+\|3D-(3,5/4)-trihydroxycyclohexane-1,2-dione-acylhydrolase-(decyclizing)	gnl\|CDD\|226471	COG3962, COG3962, Acetolactate synthase [Amino acid transport and metabolism].	0
NZ_CP045145.1\|WP_002213775.1\|1259953_1260412_+\|IS200/IS605-like-element-IS1541B-family-transposase	gnl\|CDD\|224854	COG1943, COG1943, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.50747e-46
NZ_CP045145.1\|WP_002210304.1\|1278947_1280918_+\|5-dehydro-2-deoxygluconokinase	gnl\|CDD\|378281	pfam09863, DUF2090, Uncharacterized protein conserved in bacteria (DUF2090). This domain, found in various prokaryotic carbohydrate kinases, has no known function.	0
NZ_CP045145.1\|WP_002210297.1\|1269302_1270829_+\|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase	gnl\|CDD\|143404	cd07085, ALDH_F6_MMSDH, Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2. Methylmalonate semialdehyde dehydrogenase (MMSDH, EC=1.2.1.27) [acylating] from Bacillus subtilis is involved in valine metabolism and catalyses the NAD+- and CoA-dependent oxidation of methylmalonate semialdehyde into propionyl-CoA. Mitochondrial human MMSDH ALDH6A1 and Arabidopsis MMSDH ALDH6B2 are also present in this CD.	0
NZ_CP045145.1\|WP_002223316.1\|1266912_1267461_-\|DUF1440-domain-containing-protein	gnl\|CDD\|226008	COG3477, COG3477, Predicted periplasmic/secreted protein [Function unknown].	1.03166e-68
NZ_CP045145.1\|WP_002209746.1\|1255014_1255416_-\|DUF1240-domain-containing-protein	gnl\|CDD\|336520	pfam06836, DUF1240, Protein of unknown function (DUF1240). This family consists of a number of hypothetical putative membrane proteins which seem to be specific to Yersinia pestis. The function of this family is unknown.	5.05571e-40
NZ_CP045145.1\|WP_002210306.1\|1282000_1282816_+\|5-deoxy-glucuronate-isomerase	gnl\|CDD\|226241	COG3718, IolB, Uncharacterized enzyme involved in inositol metabolism [Carbohydrate transport and metabolism].	3.14642e-169
NZ_CP045145.1\|WP_002209745.1\|1256937_1257183_+\|transcriptional-regulator	gnl\|CDD\|372675	pfam13693, HTH_35, Winged helix-turn-helix DNA-binding.	5.27401e-36
NZ_CP045145.1\|WP_002209749.1\|1253796_1254369_+\|Hcp-family-type-VI-secretion-system-effector	gnl\|CDD\|213799	TIGR03344, VI_effect_Hcp1, type VI secretion system effector, Hcp1 family. This family includes Hcp1 (hemolysin coregulated protein 1), an exported, homohexameric ring-forming virulence protein from Pseudomonas aeruginosa. Hcp1 lacks a conventional signal sequence and is instead exported by means of the type VI secretion system, encoded by a pathogenicity cluster of a class previously designated IAHP (IcmF-associated homologous protein). Homologs of Hcp1, in this protein family, are found in various bacteria of which most but not all are known pathogens. Pathogens may have many multiple members of this family, with three to ten in Erwinia carotovora, Yersinia pestis, uropathogenic Escherichia coli, and the insect pathogen Photorhabdus luminescens. [Cellular processes, Pathogenesis].	2.31704e-76
NZ_CP045145.1\|WP_002223323.1\|1275171_1276719_+\|sugar-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	0
NZ_CP045145.1\|WP_002210302.1\|1276730_1277759_+\|ABC-transporter-permease	gnl\|CDD\|224093	COG1172, AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism].	8.15893e-97
NZ_CP045145.1\|WP_002209748.1\|1254380_1254782_-\|DUF1240-domain-containing-protein	gnl\|CDD\|336520	pfam06836, DUF1240, Protein of unknown function (DUF1240). This family consists of a number of hypothetical putative membrane proteins which seem to be specific to Yersinia pestis. The function of this family is unknown.	7.32611e-43
NZ_CP045145.1\|WP_002210300.1\|1274193_1275123_+\|sugar-ABC-transporter-substrate-binding-protein	gnl\|CDD\|380623	cd19968, PBP1_ABC_IbpA-like, periplasmic sugar-binding protein IbpA of an ABC transporter and similar proteins. The periplasmic binding protein (PBP) IbpA mediates the uptake of myo-inositol by an ABC transporter that consists of the PBP IbpA, the transmembrane permease IatP, and the ABC IatA. IbpA shares homology with a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein superfamily, which consists of two domains connected by a three-stranded hinge.	4.31227e-120
NZ_CP045145.1\|WP_138921619.1\|1257395_1259708_-\|penicillin-binding-protein-1C	gnl\|CDD\|273954	TIGR02073, Includes:_Penicillin-insensitive_transglycosylase, penicillin-binding protein 1C. This subfamily of the penicillin binding proteins includes the member from E. coli designated penicillin-binding protein 1C. Members have both transglycosylase and transpeptidase domains and are involved in forming cross-links in the late stages of peptidoglycan biosynthesis. All members of this subfamily are presumed to have the same basic function. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	0
NZ_CP045145.1\|WP_002210303.1\|1277782_1278916_+\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	2.07432e-69
NZ_CP045145.1\|WP_002210294.1\|1260527_1266506_-\|alpha-2-macroglobulin-family-protein	gnl\|CDD\|225248	COG2373, COG2373, Large extracellular alpha-helical protein [General function prediction only].	0
NZ_CP045145.1\|WP_002227877.1\|1281070_1281991_+\|myo-inosose-2-dehydratase	gnl\|CDD\|275172	TIGR04379, myo-inositol_catabolism_protein, myo-inosose-2 dehydratase. Members of this family include the enzyme myo-inosose-2 dehydratase, product of the gene iolE, as found in inositol utilization cassettes in many species. [Energy metabolism, Sugars].	8.43662e-165

>NZ_CP045145.1|WP_002223316.1|1266912_1267461_-|DUF1440-domain-containing-protein
MSEKRVNLQVIAWATIIGGFVSSLVKSGTEVNMPPRVVGEISPPAANIDAWLGWLGINSHSMDYVYQGVTISGAVVLYHWLFSFVFAFVYVLLSAYWPKVRLWYSAAYGLSITVAIHGVLIPALGFRHPAYLAGETGWLWNLNGYELWSEIIGHLCWSASLEICLVAVLAFFSKPIKGIWAN
>NZ_CP045145.1|WP_002210294.1|1260527_1266506_-|alpha-2-macroglobulin-family-protein
MDLLRFLLISPFALIKGLYRLSAYLLRLVGRLLRPVVGNLNWRAPQWMTKTANGLHCAFNRSEQWVAKHPKGISAAIVLLMAAASAAFYGYHWYLNRPQPIEPAPMVYQETSIRVSAPRTVNYQAQKPEAQPLSLNFMHSAAPITAMGQVVDQGISLTPAIEGEWKWATERTLVFTPKKAWPMGANYQITIDTEKLLAPQIKLNQTELNFTTPAFAYQLEKAEYYQDPQEAQKRSTIFHVQFNAPVDVASFEKQILLGLVEGKSKSEKKLNFSVVYDEKKLNAWIHSQPLMPMDKGGSVHLSINKGVNASVAATPTTQAQNKWVSVPNLYSLAVNSINATLVESDNNNGERALIIAISDAVKDKEIKNAVKAWLLPQHNFQAKESAKTSTDFYPWDMDDIDDNLLQQSTPLALTLNEAEQEYQPIFSFKFDAPSYRTLLIEVNNSLTSVGGYKMPEKIYQIVRVPDYPKTLRFMSQGSLLSMQGDKQISVAARNMTGMKLDIKRVIPSQLQHIVSFKSSEYSSAHFNRLSDEYFTEHFQYQTALNNDNPGEINYQGVDLSRYLANNPSARRGVFLLTLSAWDPEKRDNQQHSEEDYDEDQEWVGDSRFVVITDLGIITKQSQDRSRDVFVQSIHSGLPAADAKVSVVAKNGVVLLSQITDSKGHVHFPALDAFKNERQPVMFLVEKEGDVSFLPTRATYDRNLDFSRFDIDGEETPSDPRTLSSYLFSDRGVYRPGDRFNIGLITRTANWATALDGVPLRAEIRDPRDTLMSTLPITLDSSGFNELSYTTGENSPTGEWNVYLYLVGKNNETSMLLGHTTVNVKEFEPDRLKVQLQLTPERQQGWVKPQELQANINVQNLFGTPAQERRVTSRLILRPMYPSFAPFPDYLFYENRHNSDGFETELEEQTTDLQGMATIPLDLKSYADATYQLQLLSEAFEAGGGRSVAATARVLVSPYDSLVGVKADGDLSYINRDAVRKLNIIAVDPSLNKIALPDLSLSLIEQKYISVLTKQDSGVYKYQSRLKEQLVSEQPLQISPTGTDFTLVTQQPGDFILVVKDSQGQVLNRISYTVAGNANLTRSLDRNTELKLKLNQAEYLQGEEIEIAINAPYAGSGLITIEKDKVYSWQWFHSDTTSSVQRIRIPPAMEGNGYINVQFVRDVNSDEIFMSPLSYGVMPFKISTKARQAAIELASPSVIKPGEVLPIKVTTDSPQRVVVFAVDEGILQVARYRLKDPLDYFFRKRELSVQSAQILDLILPEFSKLMALTSAPGGDAGEGLDLHLNPFKRKQDKPVAYWSGITEVNGETTFNYPIPDYFNGKIRVMAISATPDRIGKVQTSTTVRDNFILTPNVPAMVAPGDEFDVTVGVSNNLQGLKGKAVDITVRLTPPPQLEVVGEAQHSLSLAEKRETLVSFRLRARSALGDAPLVFDASYGSQSSRRTVSTSVRPAMPFRTQSVMGRMEGNKHTVTNLRQMFDNYAQRQATASHSPLVLTQGLARYLADYPYYSSEQIVSRSIPLIMQSKHPEMDSALNQNEVRDQLKNMLRILSSRQNSTGAIGLWHASPTPDPFVTPYVVQFLLEAKSAGYSLPNDILEGANNALRLLAARPYDDLYSLRLRAFAVYLLTLQGEITTNTLASVQSTLQQLYPDSWQTDLSAIYLASSYRLLKMDDEANKLLQPTWKQLGKAYSKAWWTQNYFDPLVQDATRLYLITRHFPEKVSSIPPQALENMVLALRDEHYTTYSSAMSILALESYTSQVAAQQDTPETLQIIEISKSKGIDPNVISTLNGLFVQGDFTGEAKAIQFNNYASAPAWYVVNQSGYDLQPPKDAISNGLEISRSYTDEQGKPVTQVTLGQKVNVHLKIRANAKQGQNNLAIVDLLPGGFEVVQQTAPEPEFYDNQDDQDEETGSGWQSPLMVSGSSWYPDYSDIREDRVIIYGSASTDVKEFIYQIKSTNTGRFVVPPAYGEAMYDRNVQALSVGKGHILVVPPEAK
>NZ_CP045145.1|WP_002213775.1|1259953_1260412_+|IS200/IS605-like-element-IS1541B-family-transposase
MRDEKSLAHTRWNCKYHIVFAPKYRRQVFYREKRRAIGSILRKLCEWKNVNILEAECCVDHIHMLLEIPPKMSVSGFMGYLKGKSSLMLYEQFGDLKFKYRNREFWCRGYYVDTVGKNTARIQEYIKHQLEEDKMGEQLSIPYPGSPFTGRK
>NZ_CP045145.1|WP_138921619.1|1257395_1259708_-|penicillin-binding-protein-1C
MALFLLALLVIGFRLWPHPPLSQGLPLSTAYYDRHGTLLRLSLANDDRYRLWTPLEEISPLVIQGIQLHEDRGFYYHPGVNPISLLRGFWQSYVQGGRQQGGSTLTMQLARMHWHLNTRSPTGKLRQIARAIQLELSYSKHDILEAYLNYAPYGRNIESIAAASLIYFDKKPQQLTLPEALTLAVLPQSPSYRIDPTTGVLGSALTQARNRLFVRWQQTYPTDSSQMALFQLPLSLRQPEKMPYIAPHFIEQIRRQNQQLANTQSQVDTTLDANLQQLVEKQVEAFIRRNNSRGIHNAAVLLLDTRDMGVRALVGSANYYDREIQGQVNGTNAKRSPGSTLKPFIYALGLEQGILHPMTILKDVPSSFGAYAPENFDHRFLGPVTATDALNFSRNIPAVYVASRLRQPTLYQFLRLSGVTNMASENHYGLSLVLGGGEITLQELARLYAMLANRGTLHPIQMVQTDKTLPSIRLLSEAASFITLDMLRQHRRPGDTLAQSPTSLPVYWKTGTSWGFRDAWSAGIFGPYVLIVWEGNFAGKGNSAFVGADAAAPLFFNIIDSIQANYPALREPKHPWPPQLKRVAICLASGNLPTPWCQQQGKTWFIPGKSPIKVDTVYRPVVIDINSGQAACLPYDRSQTRTEVFEFWPSDLANVFAQAGLPKRQPPDRSHCKEGNTLASGNAPRITSPLRNTTYTLRQSQQGRDQIVFSATLDADSTTTYWFVDDIYLGSSTSKKSIDWHPTRSGQYRIRAIDDHGRADSRLIRVEKVD
>NZ_CP045145.1|WP_002209745.1|1256937_1257183_+|transcriptional-regulator
MDKQDWHPADILAGLKKRGTTMAALSRKSGLASSTLANTLLRPWPKGERLIAEVLELHPAEIWPSRYLKPKKSPAESVNPG
>NZ_CP045145.1|WP_002216002.1|1255683_1256265_-|hypothetical-protein
MKYNSVLKTFVDDDYRLEDHLDFKKQHADIRYQKLHKQLNEMSDENMHALLTIEEGEYFLKTLCNPNPHQSWKDAIFSCTDPTSVFFGSLVESLSVSRIVFEIRGFGVTATEYVGKNGSSYIKLSGYAGIRKYLDATRYLIDNPKILDIGIGTQGIENGIVRGARFCIVFSAAYRSVELLLKDEYGLADFLLI
>NZ_CP045145.1|WP_002209746.1|1255014_1255416_-|DUF1240-domain-containing-protein
MVKINRPLVGAFAILLFFLSSWGCWFSLSGYLAFFKLSDVIIFSWKVGFVIFAVPLLFYFSYLAFFSAIKNKPAIMNNKLANALAILAILGSIISLFSSAYISYSLTEYSYKSCPRSSWMSPNKYVKDIKLCP
>NZ_CP045145.1|WP_002209748.1|1254380_1254782_-|DUF1240-domain-containing-protein
MVKINRPLFGAFAVFLLFLSCWVSWFSLNGYWDFFKLSDVIIFSWKVGVMIFGAPVLFYFSYLAFYCAIKNKPAKVNNKLANTFAMLAMLGVVISFFSSVYIGYSLTEYGYKLCSRSSWMSPNEYVKDIKLCP
>NZ_CP045145.1|WP_002209749.1|1253796_1254369_+|Hcp-family-type-VI-secretion-system-effector
MSNLIYASVNGKKQGLISAGCSSLNSIGNRCQAGHEDQIQVLSLNHSISRQQNVAHHPVHFVKPIDKSSPLLGVAISENERINVVFYFYRVNSAGQLELYYEVKLTDASIVDITSVYPHSIDNNEMIPYEKIQLKYKSIAWDHKSAGTSGYSVWEDRVYSFLISSTLFQVCLNIFIFFNWLVYQNYFWEK
>NZ_CP045145.1|WP_002227852.1|1253521_1253773_+|hypothetical-protein
MMKNNKNINKDEFSDKLSQQIKEMINNSQLDSVEILSVVMESIFSLFSETEGHLAEMKFIDSAGEDYRFILRLEVPPILERQH
>NZ_CP045145.1|WP_002210296.1|1268094_1268949_-|MurR/RpiR-family-transcriptional-regulator
MTTASNLSELQQQIRDRYDNLSKRLQQVSRYVLDNTNSVAFDTVAVIAERADVPPSTLIRFANAFDFSGFNEMKQLFRMNLVEETASYTDRARLFRAMESEAVPETPLGILQEFARSNAQALQQLAARTEPEMLQRAVELLAQADTIYVVGLRRSFSVAAYLTYALSHLECRPVQLHGLGGMLREQVNSIKARDIVVSISFSPYAEETVMVSEIAASAGARQIVITDSQISPLATFSDLCFVVKEAQVDAFRSQSATLCLVQSLVVALAYQQEAQAGAALAHRQ
>NZ_CP045145.1|WP_002210297.1|1269302_1270829_+|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase
METVANFINGKCVFSCGNSVTSGSPRAQAIFNSATGEPIRQVMMSTAQETEQAITAAQQAFASWSRQAPLKRARVMFRFKSLLEQHLDALAQLISEEHGKVYSDAVGELTRGLEVVEFACGIPHLQKGEHSANVGTGVDNHSLMQPLGVCVGITPFNFPAMVPMWMFPIALATGNTFVLKPSEKDPSLAVRLAQLLTEAGLPDGVFNVVQGDKTAVDVLLTDPRVQAVSFVGSTPIAEYIYQTASAHGKRCQALGGAKNHCILMPDADMDMAASAIMGAAYGAAGERCMALSVVLAVGDETADNLCARLEQQISTLRVGPGLAQEPENDMGPLISAPHRAKVLGYIDSGVAQKATLRIDGRGLKVAGHEQGYFVGPTLFDHVTPAMTIYQEEIFGPVLSVVRIADYRSAVDLINRHEYGNGTAIFTRDGGTARRFCEEVQVGMVGVNVPIPVPVAFHSFGGWKRSIFGPLNVHGNDGVRFYTRMKTITARWPEAQHDQGAAFSMPTLG
>NZ_CP045145.1|WP_002359655.1|1270863_1272789_+|3D-(3,5/4)-trihydroxycyclohexane-1,2-dione-acylhydrolase-(decyclizing)
MKTVRMTMAQALVRFLNQQYVAIDGQEVAFVHGVMTIFGHGNVLGIGQALEENPGHLQVHQGCNEQGMAHMAIGFAKQYRRQRIYAVSSSIGPGAANMVTAAATATANRIPLLLLPGDIYASRQPDPVLQQIEQYHDLSISTNDCFRPVSRYWDRINRPEQLMSAMLSAMRVLTDPADTGAVTLCLPQDVQGEAWDYPASFFERRVHRIERRPPDTRRLSDALSLIARKRRPLVVCGGGVRYSGAHEAFRAFVENAQLPFTETQAGKGALPSDHPLNLGGIGVTGGLAANRLAPQADLVIGIGTRLTDFTTGSKALFSHPEVAFLLLNVAEFDALKLDATALIADARVGLEALTEGLAGYRTAWQGDIIEAKAAWCDECQRLWSRTWRPDEVPEVAGHLDDSLQEYAEVLNTTLTQTRVLGLINQHIEDDAIVVGAAGSLPGDLQRLWQVKTADTYHLEYGYSCMGYEIAAAIGAKIAMPHQPVYAMVGDGSYMMLHSELHTAVQEGLKITVLLFDNAGFGCINNLQMGHGMGSFCTESRHRNHESGQLNGPLICVDFAQNAESYGCRAWRVHDEPSLLAALAASRDHPGPVLLDIKVLPKSMTHDYASWWRTGDAQIARSPAVQQAAERTQMKVKRARQY
>NZ_CP045145.1|WP_002210300.1|1274193_1275123_+|sugar-ABC-transporter-substrate-binding-protein
MKKLILAALIVFTSGVAFAENEQIVFSTPNLAMPFEVHMQRTAVKTAKALGVKLQVLDGQGSSPKQVADLENAITRGAQGFIVSPNDINAISSAVEEIQQAKLPVVTLDRSVESEKKVPHFGANNYKGGEAIANYVKSMFPNGAEIVLLTGQPGSSSNIERTKGIRDSLKTGGDKYRIVVDQTGNWMRSEGMRIIESVLPSLPKPPQVILSANDDMALGAIEALQSHGMKPGEIMVTGFDAVPEALARVREGWMAVTADQRPGYAVTTAMNQLVANIRDQKAITGADFLPTMITKENLDQAERVSEAGK
>NZ_CP045145.1|WP_002223323.1|1275171_1276719_+|sugar-ABC-transporter-ATP-binding-protein
MSQPLLKITDMAKSFSGVWALSNVQLTLEQGEIHALLGENGAGKSTLLKALSGAQPQTHGEIWFNGEMLALDDSPVERQNKGIITIYQEVNLLPNMTVAENMFLGREPRRRQVFVDEKAVNQEAQAILDYLQLNVSPTTAVARLSIAQQQMVEIARALTLNAKLIVMDEPSAALSDSEVESLHRVVRELKGRGVSIIYVTHRLHEVFQLCDRFTVFQDGRYTGSDEVAGTNVEKIIRLMVGRDVVFNRRPASETHHQDQPIRLSVQGLCREKPPLDPHGVALKDISFHVHAGEVLGIAGLVGAGRTEVARCLFGAGAFTSGNFEIDGVPYQPRDPMFALEQGIALVPEDRKKEGAVQGLSIRDNLTLSSLAGLLQWRFFVNTRKEDQLIETYRLALQIKMVNSEQAVRKLSGGNQQKVILARCMALNPRILIVDEPTRGIDVGTKSEVHQVLFDMAKQGVAVIVISSDLPEVLAVSDRIITLSEGRVTGEIHGDDASEERLMTMMTINHNALNAA
>NZ_CP045145.1|WP_002210302.1|1276730_1277759_+|ABC-transporter-permease
MLQPLSKPQASVKSAMRFDPITFFERFGVLIFMFLLLIFFQLQNSNFLSERNIFNILTEVSIYGIMAVGMTFVILTAGIDLSVGSILAVSAMTAAYVIKGDNFTTIDPNAWGGMSWLIGLSICLAMGTLIGFLQGLGVTRLRLPPFIVTLGGMTIWRGLTLVINDGAPIAGFDAGYRWWGRGDLLGISIPIWIFAIVAIAGYLALHKTRWGRFVYAIGGNPEAARLAGVNVKRVLVSVYVVIGCLAGLAGFILSARLGSAEAVAGISFELRVIASVVIGGTSLMGGYGRIGGTIIGSIIMGILINGLVLMNVSAYYQQIITGLIIVLAVAFDTYAKNRRGAL
>NZ_CP045145.1|WP_002210303.1|1277782_1278916_+|Gfo/Idh/MocA-family-oxidoreductase
MKEVRIGLIGTGYIGKAHAIAYAQAPTVFELRGKLVREMVAEVSPALAAQRAQAFGFNRFTCDWRELVADPAIDVVDICSPNYLHKEMALAAIHHGKHVYAEKPLALNARDASEMAAAATRAGVKTLVGFNYIKNPSAKLAKEIIERGEIGEVIHFYGTHNEDYMADPNTPIHWHCLHATAGLGALGDLAAHIVSMAQYLVGEITQVCGDLKTVVVTRPASVGSSARVAVENEDQAHAMVRFVNGAQGVIEASRVACGRKMGLSYMITGTQGAISFTQERMAELKLYLHNDPVNRQGFRTLLVGPAHPEYAAFCMAAGHGIGFNDQKTVEVRDLIDGIAMDTPLWPDFAEGWKVSRILDAIALSHQDSRWVNVTDIV
>NZ_CP045145.1|WP_002210304.1|1278947_1280918_+|5-dehydro-2-deoxygluconokinase
MSVEKQFSVSAEKTCNTENKCNTEKKFDVICMGRIAVDLYGQQIGARLEDVASFAKYLGGSSGNVAYGSARQGLRSSMLARVGDEHMGRFLREELHQVGCDTSHLTTDKKRLTALVLLSIKDRDTFPLIFYRDNCADMAITAQDFSEQYIASARSLAITGTHLSHPNTREAVLTALRYARRNGVRTVLDIDYRPVLWGLTSLGDGETRFIESHQVTAELLAVFNLFDVIVGTEEEFHIAGGSTNTLDALRGVREVSDAALVCKRGALGCSVYTEAIPQTLDEGLTVSGVRVKVLNVLGAGDAFMSGLLRGYLNDEGWPQACRYANACGALVVSRHGCAPAMPSKIELDNYLARADAVVRPDLDVHLNHLHRVTTRRRQWPELCVMAFDHRSQLEEMALQCGADLCHISTLKTLILQASREAVHTAGLQGKAGLLCDGTFGQDALNAITGAGWWIGRPIELPGSRPLAMEHGNIGSQLIGWPQEHIVKCLVFFHPEDAYSLRLEQEQKIIEVYRACCQSGHELLLEVILPAGMPRSDELYLRAISRFYNLGVYPDWWKLPPLASEGWAALNKLIERRDPHCRGVVILGLDASLEALRTGFNAAAGYPIVKGFAVGRTLFGDASLAWLKRDIDDTQLIARIRDNYLQLITLWRERGQK
>NZ_CP045145.1|WP_002227877.1|1281070_1281991_+|myo-inosose-2-dehydratase
MRKTEADRHTTAVQLGINPLTWTNDDLPSLGAETSLETCLSEGKEAGFAGFELGNKFSREAGVLGPILEHHQLKLVSGWYSGRLLERSVEEEIVAVRSHLALLRELGAKVMVFAEVSGCIHGEQQTPVHLRPRFPPARWAEYGAKLTAFARYTQALGVQIAYHHHMGTVIESAQDIDNLMIHTGEEVGLLLDTGHLTFAGADPLAVAQRWIARINHVHCKDVRTSVLADVKNRKTSFLDAVLSGVFTVPGDGGVDYPPIMALLKQHGYQGWLVVEAEQDPNVAHPMTYARMGYHNLSRLAHNAGLI
>NZ_CP045145.1|WP_002210306.1|1282000_1282816_+|5-deoxy-glucuronate-isomerase
MSRLLSRRQAPDERGLTQRITPAQAGWGYVGFEVYELNEGQPLTLTAVPDERCLVLIAGRASISTPSAQFPNIGDRMSPFERHKPWAVYVTPGEAVQVQAITPLELAVCSAPGKGTYPTRLISPEDIGAEARGKGHNQRYVHNILPEDHPADSLLVVEVYTNEGASSSYPSHKHDTDNPPHETYLEETYYHRLNPEQGFCMQRVYTDDRSLDECMAVYNREVVMVPRGYHPVATMAGYDSYYLNVMAGPVRKWIFSWENDHVWINHNYPIT

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Crispr_ID: NZ_CP045145_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045145_3

1877657-1878104

TypeI-F

I-F

Consensus_repeat	Method
GTTCACTGCCGCACAGGCAGCTTAGAAA	PILER-CR
GTTCACTGCCGCACAGGCAGCTTAGAAA	CRISPRCasFinder
GTTCACTGCCGCACAGGCAGCTTAGAAA	CRT

7 spacers

cas1,cas3f,cas8f,cas5f,cas7f,cas6f

The CRISPR arrays of NZ_CP045145_3

>merge|NZ_CP045145|3|1877657-1878104|PILER-CR,CRISPRCasFinder,CRT
GTTCACTGCCGCACAGGCAGCTTAGAAACTGATGGGTAACTTTAATCCCAAATTCTTTTTGTTCACTGCCGCACAGGCAGCTTAGAAATGTTAAATCGTCGCCTAAATTTGTTTGACCGAGTTCACTGCCGCACAGGCAGCTTAGAAAGTGGAATGGCTATTGCTATCGCTCGAGAATATGTTCACTGCCGCACAGGCAGCTTAGAAATCGCGAACGCGCTCAGGTTCACGGAATGGCGAGTTCACTGCCGCACAGGCAGCTTAGAAAATCTGCGCCAAAGAAAATGCCATTCAGATAATGTTCACTGCTGCACAGGCAGCTTAGAAAAACTACTAGAAGCTTGCCCATCTTACCTTTTCGTTCACTGCCGCACAGGCAGCTTAGAAAATCATGAAAGACATTGTTCGCCAGTCCCCTGAGTTCACTGCCGCACAGGCAATAATCAAA

>NZ_CP045145|3|3|1877657-1878044|PILER-CR
GTTCACTGCCGCACAGGCAGCTTAGAAA	CTGATGGGTAACTTTAATCCCAAATTCTTTTT
GTTCACTGCCGCACAGGCAGCTTAGAAA	TGTTAAATCGTCGCCTAAATTTGTTTGACCGA
GTTCACTGCCGCACAGGCAGCTTAGAAA	GTGGAATGGCTATTGCTATCGCTCGAGAATAT
GTTCACTGCCGCACAGGCAGCTTAGAAA	TCGCGAACGCGCTCAGGTTCACGGAATGGCGA
GTTCACTGCCGCACAGGCAGCTTAGAAA	ATCTGCGCCAAAGAAAATGCCATTCAGATAAT
GTTCACTGCTGCACAGGCAGCTTAGAAA	AACTACTAGAAGCTTGCCCATCTTACCTTTTC
GTTCACTGCCGCACAGGCAGCTTAGAAA

>NZ_CP045145|3|2|1877657-1878104|CRISPRCasFinder
GTTCACTGCCGCACAGGCAGCTTAGAAA	CTGATGGGTAACTTTAATCCCAAATTCTTTTT
GTTCACTGCCGCACAGGCAGCTTAGAAA	TGTTAAATCGTCGCCTAAATTTGTTTGACCGA
GTTCACTGCCGCACAGGCAGCTTAGAAA	GTGGAATGGCTATTGCTATCGCTCGAGAATAT
GTTCACTGCCGCACAGGCAGCTTAGAAA	TCGCGAACGCGCTCAGGTTCACGGAATGGCGA
GTTCACTGCCGCACAGGCAGCTTAGAAA	ATCTGCGCCAAAGAAAATGCCATTCAGATAAT
GTTCACTGCTGCACAGGCAGCTTAGAAA	AACTACTAGAAGCTTGCCCATCTTACCTTTTC
GTTCACTGCCGCACAGGCAGCTTAGAAA	ATCATGAAAGACATTGTTCGCCAGTCCCCTGA
GTTCACTGCCGCACAGGCAATAATCAAA

>NZ_CP045145|3|2|1877657-1878104|CRT
GTTCACTGCCGCACAGGCAGCTTAGAAA	CTGATGGGTAACTTTAATCCCAAATTCTTTTT
GTTCACTGCCGCACAGGCAGCTTAGAAA	TGTTAAATCGTCGCCTAAATTTGTTTGACCGA
GTTCACTGCCGCACAGGCAGCTTAGAAA	GTGGAATGGCTATTGCTATCGCTCGAGAATAT
GTTCACTGCCGCACAGGCAGCTTAGAAA	TCGCGAACGCGCTCAGGTTCACGGAATGGCGA
GTTCACTGCCGCACAGGCAGCTTAGAAA	ATCTGCGCCAAAGAAAATGCCATTCAGATAAT
GTTCACTGCTGCACAGGCAGCTTAGAAA	AACTACTAGAAGCTTGCCCATCTTACCTTTTC
GTTCACTGCCGCACAGGCAGCTTAGAAA	ATCATGAAAGACATTGTTCGCCAGTCCCCTGA
GTTCACTGCCGCACAGGCAATAATCAAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045145.1\|WP_002210198.1\|1869073_1869949_+\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224096
NZ_CP045145.1\|WP_002211867.1\|1885447_1886452_+\|type-I-F-CRISPR-associated-protein-Csy3	cas7f	cd09677_cas7f_CAS-I-F	gnl\|CDD\|378222
NZ_CP045145.1\|WP_002210200.1\|1866366_1867407_-\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380502
NZ_CP045145.1\|WP_002210197.1\|1869949_1870774_+\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472
NZ_CP045145.1\|WP_002211865.1\|1887094_1888114_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381305
NZ_CP045145.1\|WP_002210196.1\|1870920_1871976_+\|glycosidase	unknown	unknown	gnl\|CDD\|350124
NZ_CP045145.1\|WP_002210194.1\|1873063_1874179_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045145.1\|WP_002221142.1\|1879440_1882728_+\|type-I-F-CRISPR-associated-helicase-Cas3	cas3f	cd09673_cas3f_CAS-I-F	gnl\|CDD\|187804
NZ_CP045145.1\|WP_002210201.1\|1864961_1866350_-\|phosphomannomutase/phosphoglucomutase	unknown	unknown	gnl\|CDD\|185312
NZ_CP045145.1\|WP_002210193.1\|1874217_1875492_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045145.1\|WP_002213840.1\|1872002_1872941_+\|DUF1861-family-protein	unknown	unknown	gnl\|CDD\|378102
NZ_CP045145.1\|WP_002222491.1\|1883136_1884483_+\|type-I-F-CRISPR-associated-protein-Csy1	cas8f	cd09675_cas8f_CAS-I-F	gnl\|CDD\|274203
NZ_CP045145.1\|WP_002210199.1\|1867678_1868965_+\|carbohydrate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224567
NZ_CP045145.1\|WP_002216551.1\|1890156_1890366_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045145.1\|WP_002211864.1\|1888124_1888628_-\|formaldehyde-activating-enzyme	unknown	unknown	gnl\|CDD\|224708
NZ_CP045145.1\|WP_002211863.1\|1888674_1890033_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340874
NZ_CP045145.1\|WP_002211868.1\|1884479_1885430_+\|type-I-F-CRISPR-associated-protein-Csy2	cas5f	cd09676_cas5f_CAS-I-F	gnl\|CDD\|187807
NZ_CP045145.1\|WP_002210191.1\|1878463_1879444_+\|type-I-F-CRISPR-associated-endonuclease-Cas1	cas1	cd09718_cas1_CAS-I-F	gnl\|CDD\|132676
NZ_CP045145.1\|WP_002211866.1\|1886462_1887017_+\|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	cas6f	cd09674_cas6f_CAS-I-F	gnl\|CDD\|378224
NZ_CP045145.1\|WP_002210192.1\|1876074_1877319_-\|mechanosensitive-ion-channel	unknown	unknown	gnl\|CDD\|223740

Protein	Function_ID	Function_description	E-value
NZ_CP045145.1\|WP_002210198.1\|1869073_1869949_+\|sugar-ABC-transporter-permease	gnl\|CDD\|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	2.26211e-58
NZ_CP045145.1\|WP_002211867.1\|1885447_1886452_+\|type-I-F-CRISPR-associated-protein-Csy3	gnl\|CDD\|378222	pfam09615, Cas_Csy3, CRISPR-associated protein (Cas_Csy3). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This entry, typified by YPO2463 of Yersinia pestis, is a CRISPR-associated (Cas) entry strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy3, for CRISPR/Cas Subtype Ypest protein 3.	0
NZ_CP045145.1\|WP_002210200.1\|1866366_1867407_-\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|380502	cd06279, PBP1_LacI-like, ligand-binding domain of an uncharacterized transcription regulator from Corynebacterium glutamicum and its close homologs from other bacteria. This group includes the ligand-binding domain of an uncharacterized transcription regulator from Corynebacterium glutamicum and its close homologs from other bacteria. This group belongs to the LacI-GalR family repressors and are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the sugar-binding domain of ABC-type transport systems that contain the type 1 periplasmic binding protein-like fold. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding.	1.56156e-83
NZ_CP045145.1\|WP_002210197.1\|1869949_1870774_+\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	4.72016e-69
NZ_CP045145.1\|WP_002211865.1\|1887094_1888114_-\|aldo/keto-reductase	gnl\|CDD\|381305	cd19079, AKR_EcYajO-like, Escherichia coli YajO and similar proteins. Escherichia coli YajO is the prototype of this family. It is an uncharacterized aldo/keto reductase family oxidoreductase.	6.34333e-143
NZ_CP045145.1\|WP_002210196.1\|1870920_1871976_+\|glycosidase	gnl\|CDD\|350124	cd18612, GH130_Lin0857-like, Glycoside hydrolase family 130 such as Listeria innocua beta-1,2-mannobiose phosphorylase. This subfamily contains the glycosyl hydrolase family 130 (GH130), as classified by the carbohydrate-active enzymes database (CAZY), enzymes that are phosphorylases and hydrolases for beta-mannosides, and includes Listeria innocua beta-1,2-mannobiose phosphorylase (Lin0857). hey possess 5-bladed beta-propeller domains similar to families 32, 43, 62, 68, 117 (GH32, GH43, GH62, GH68, GH117). GH130 enzymes are involved in the bacterial utilization of mannans or N-linked glycans. Structure of Lin0857 shows beta-1,2-mannotriose bound in a U-shape, interacting with a phosphate analog at both ends. Lin0857 has a unique dimer structure connected by a loop, with a significant open-close loop displacement observed for substrate entry. A long loop, which is exclusively present in Lin0857, covers the active site to limit the pocket size.	9.75278e-165
NZ_CP045145.1\|WP_002221142.1\|1879440_1882728_+\|type-I-F-CRISPR-associated-helicase-Cas3	gnl\|CDD\|187804	cd09673, Cas3_Cas2_I-F, CRISPR/Cas system-associated protein Cas3/Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas3/Cas2 fusion; This protein includes both DEAH and HD motifs for helicase and N-terminal domain corresponding to Cas2 RNAse; signature gene for Type I and subtype I-F.	0
NZ_CP045145.1\|WP_002210201.1\|1864961_1866350_-\|phosphomannomutase/phosphoglucomutase	gnl\|CDD\|185312	PRK15414, PRK15414, phosphomannomutase.	0
NZ_CP045145.1\|WP_002211866.1\|1886462_1887017_+\|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	gnl\|CDD\|378224	pfam09618, Cas_Csy4, CRISPR-associated protein (Cas_Csy4). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This protein family, typified by YPO2462 of Yersinia pestis, is a CRISPR-associated (Cas) family strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy4, for CRISPR/Cas Subtype Ypest protein 4.	1.71931e-94
NZ_CP045145.1\|WP_002213840.1\|1872002_1872941_+\|DUF1861-family-protein	gnl\|CDD\|378102	pfam08950, DUF1861, Protein of unknown function (DUF1861). This hypothetical protein, found in bacteria and in the eukaryote Leishmania, has no known function.	6.29599e-176
NZ_CP045145.1\|WP_002222491.1\|1883136_1884483_+\|type-I-F-CRISPR-associated-protein-Csy1	gnl\|CDD\|274203	TIGR02564, conserved_hypothetical_protein, CRISPR type I-F/YPEST-associated protein Csy1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This protein family, typified by YPO2465 of Yersinia pestis, is a CRISPR-associated (Cas) family strictly associated with the Ypest subtype of CRISPR/Cas locus. This family is designated Csy1, for CRISPR/Cas Subtype Ypest protein 1.	0
NZ_CP045145.1\|WP_002210199.1\|1867678_1868965_+\|carbohydrate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224567	COG1653, UgpB, ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism].	2.85244e-50
NZ_CP045145.1\|WP_002211864.1\|1888124_1888628_-\|formaldehyde-activating-enzyme	gnl\|CDD\|224708	COG1795, COG1795, Formaldehyde-activating enzyme nesessary for methanogenesis [Energy production and conversion].	1.50048e-90
NZ_CP045145.1\|WP_002211863.1\|1888674_1890033_-\|MFS-transporter	gnl\|CDD\|340874	cd17316, MFS_SV2_like, Metazoan Synaptic vesicle glycoprotein 2 (SV2) and related small molecule transporters of the Major Facilitator Superfamily. This family is composed of metazoan synaptic vesicle glycoprotein 2 (SV2) and related small molecule transporters including those that transport inorganic phosphate (Pht), aromatic compounds (PcaK and related proteins), proline/betaine (ProP), alpha-ketoglutarate (KgtP), citrate (CitA), shikimate (ShiA), and cis,cis-muconate (MucK), among others. SV2 is a transporter-like protein that serves as the receptor for botulinum neurotoxin A (BoNT/A), one of seven neurotoxins produced by the bacterium Clostridium botulinum. BoNT/A blocks neurotransmitter release by cleaving synaptosome-associated protein of 25 kD (SNAP-25) within presynaptic nerve terminals. Also included in this family is synaptic vesicle 2 (SV2)-related protein (SVOP) and similar proteins. SVOP is a transporter-like nucleotide binding protein that localizes to neurotransmitter-containing vesicles. The SV2-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.50877e-50
NZ_CP045145.1\|WP_002211868.1\|1884479_1885430_+\|type-I-F-CRISPR-associated-protein-Csy2	gnl\|CDD\|187807	cd09676, Csy2_I-F, CRISPR/Cas system-associated RAMP superfamily protein Csy2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; predicted Cas5 ortholog.	1.12008e-157
NZ_CP045145.1\|WP_002210191.1\|1878463_1879444_+\|type-I-F-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|132676	TIGR03637, cas1_YPEST, CRISPR-associated endonuclease Cas1, subtype I-F/YPEST. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the YPEST subtype of CRISPR/Cas system.	0
NZ_CP045145.1\|WP_002210192.1\|1876074_1877319_-\|mechanosensitive-ion-channel	gnl\|CDD\|223740	COG0668, MscS, Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane].	2.65074e-32

>NZ_CP045145.1|WP_002210192.1|1876074_1877319_-|mechanosensitive-ion-channel
MQQRISQWLERLGMEFSDVMSLTMVIGLILLISVMIHLVLHRVVLAALQRRGQQSQRIWQQAITKHKLFQRVALLLQGIIINLQAVLWLQNGSQTQAVIVTAAQVWIMAFALLALFSLLDTLLALLRQSSVAHQLPLRGICQGLKLVAAIFIGIMIVSLLMGRSPLLLLSGLGAMTAVLMLVFKDPILGLVAGIQLSANDMLKIGDWLEMPKYGADGAVTDIGLTTVKVRNWDNTVTTIPTYALISDSFKNWRSMSESGGRRIKRSINIDTTSVHFLSEQEQQRLTLNPLLQHYLSEKSQELNQYNQQIALDLSSPLNGRRLTNIGTLRAYLVAYLRAHLGIHQSMTLMVRQLAPTPEGLPLEVYAFTNTTIWAEYEGIQADIFDHIFAVVSEFDLRIHQTPSGNDMRSMLAKV
>NZ_CP045145.1|WP_002210193.1|1874217_1875492_+|hypothetical-protein
MKLLNTLVCIIGLTSFSSSAKLVNAEHLDALYQKVTVANKTELGLIHIYSEFPDYRWVKDPIEGVSAIDDVARAAIFYQRQYQATGSAADLEKVKSLVEFILYQRADNGYFYNFIYPDHSINKEYKTSVAEPNWWTWRALWALTQVYPTLVKTDNALAQRTRETIFATIDVIYKDFNFKQTRGEKEGVAVPEWLPHTAGDQASVLLMALSDAQALEAKPEIEKMMRSLAAGIMLMQVKDTSSPVNGAFLSWQNLWHGYGNSQAYALLVAGNRLGDRDMIKAAFNELDHFHPWLISNGLLNEFTVRQQGEKVTLIEQKKFSQIAYIIRPMVFANIKAWEISRDAVYLERAVDLSLWFFKNNPAQAQMYYPVTGIAFDGIDSATTVNKNSGAESTIEALLTLQLIESIPDAKRMLESALEKRNIKQ
>NZ_CP045145.1|WP_002210194.1|1873063_1874179_+|hypothetical-protein
MKHKKYLPLFLMAGICSVAQADNSPDVVSANNMDNRTFFAGDKIRIVKDGGETIEAVVELSDDNIGIVRIPKDEKAYFHGNWLAEYKIEHFRNEGRSTNSRPVHEIVFADGRVNFGDTGWNTGFLLKQVRFTSDSRNESNHKVDFRMVEMEIRPAWSKSIDKHWFMFEGIYLGKTGYEKNRTTGGDNNIGGDGYGFRPYYRYQVSDRLSVNTDVKMLVEDKDARGADNGRFQFYEALVNVNYRVADNVHVGIEVFRKEGQDFNHNGTKTANVLEQELRPWVAWNMGKNNFLFKMEPQLRRIGGQDGYRETSKAQKYIFNYSYPIADRVYLVAEYFYRVEHDKKFWDRGVRDNKSYSDTTTHFGKLGINYIF
>NZ_CP045145.1|WP_002213840.1|1872002_1872941_+|DUF1861-family-protein
MMRHAPPASVAQLFADYQKRTAHNTFSTGRLEFTGVGDKDVYNITAPFTSAGQVVIAGRVEARDSEHSTIVFFSEQQGQWAPVENAPTFQLQDPFFTRIEDELILGGVEINPHPDNPRQLIWHTVFFRGRDIHSLTRFASGPPGMKDIRLCHIQQGRIGVFTRPQGKIGGRGTIGYVEINNLEALTPETITSAELFEQQFNSEEWGGVNETHLLCDGTIGLLSHIACFDQHGRRHYYPGVFIFNPDTKNYTPIKIIAARDNFLPGATKRPDLVDVIFPGGLIVLPNNGWRLYVGASDAEAHWIDIEDPFSGF
>NZ_CP045145.1|WP_002210196.1|1870920_1871976_+|glycosidase
MMRYSGNPLITPQDITPSHPGFKVECAFNAGITKLGDETIMLIRIAESVIPESEGITVVPLLMEISGHWQVTTRVFKHDDPAYDFSDPRLISDIADPSTVYLTSLSHLRVARSHDGVTFVVDDQPFIFPANGDEAFGCEDARITQIDGAYYINYSAVSAKGICTALAVTQDFTDVKRLGLIFCPDNRDACLFPEKINGKYMTLHRPAPKHFGKPEIWLASSLDLLHWGDHRHLLGTSQDPWDALKLGGGAQMLKTEKGWLQIYHGVDATQRYSLGALLLDLEQPTKILAKSPVPLLQPQAPYELHGFFGNVVFTCGALIENDSLRVYYGAADECMCLAEMPLAQLWQHLSV
>NZ_CP045145.1|WP_002210197.1|1869949_1870774_+|carbohydrate-ABC-transporter-permease
MKKNINSLIIHLVMFSLALSWLYPYIWMVLSSFKQSADIYTTGLFGSAYSLDNYRFLFENSGRVEKPFLKTLFNSLFISTVVTVAVTLSSMFIGFALAKMQFKGQSLFRNLLFLQMVFPASMFIIPQFVLVRELGLLNTYSAMIVPFLMSSWGIFMISQSFQGTPNDYIHAAKIDNASLWQIMIYLMMPLNKAIIAIVALFTFVGTWDNFLWPLIVIQDESKMPLSVLLATFSKSYGVYVGPVIAGAVIQTIPIVVLFILFRKYFMQGMSLSLK
>NZ_CP045145.1|WP_002210198.1|1869073_1869949_+|sugar-ABC-transporter-permease
MTFLKLKDKQVGSVLAASYLGYTSIFWFYPFIWLAVLSLTEWRFVGIPTFNGLNNFILVMQDPLFWKSMLNVMRFLMYYLPIVFISSFLFAFGLQKLKHGRTFVALSFLLANVSSGVAYSIVFSKIFSQNGPLNTFLYDWFGFTLPWLTSPDFAMLSIALVVTWKFVGYYGLILFSGLNSIPKEIYSAAELDNTRTIKRLFHITLPMINPQLIMVLVLAITVSFAIFTEPYLITGGGPLNSTTTPMIVMYETAFMKMQPSWAATMSIFIALISFGIILGVRKLLERKVEIV
>NZ_CP045145.1|WP_002210199.1|1867678_1868965_+|carbohydrate-ABC-transporter-substrate-binding-protein
MLEKMKNTLISLAIASSCVVFTGCDNDTASAKNEKQDITLWIAPNNVQEAFWSEVVGEWNKQPDKKKVVFSTIPAAGSSEEAIMNAIASDRAPDISENIFTGFGSQLADLGQVVDLSTLDGYENLISTRQMTDIMDNWRYNGKNYILPIYMNPVLFWWRGDLLKEQGFSEVPKTYDEVYALSEKYTIPDKRYAIQATSGRNWWDRWFDFIALYYAQSDGKPYIANQQASYDNQAGRDVLDFMHTLFSKKWTLYDFGQDDPLVTGKVLGAVRGPWDISRYQQQYPEILKHIKMGPMLVKEQQDKPHTFADGKGLVLFSHSKVKPEAWEFIQWVFSQPKFDKRWMELTGMPPARADLLTNPFFAEYYQEHPYAAAYAEYVNVAIPPVSSGETVEIQRSMTQMIEKTAFNTATPDEALQQSIKEVNAILKP
>NZ_CP045145.1|WP_002210200.1|1866366_1867407_-|LacI-family-DNA-binding-transcriptional-regulator
MTTGKKRETLKTIAETLNVTHTTVSNVFNRPEKVSPELREKILAYAESINYHGPAGAGRFLRTGKCGTLGVIFNDNLSYVFSDRHDIALMRGIAEECEKNGINIALMPLKTNNALKKRMMGALVDGYILNATYNNDEVVQAALTSGLPVITTDIKLQNFTCVSIDDGAAMQAICHHLLAAGHKKFGIVSFPVKRLPGELTSLAEFSTDYDNGVAFGRISACITALSDAGIDLHTSYVAEQPHSETGGEKAAKALLAKEPGISAIICLSDRFAFGVYQFCQDHNIPVPGQIAITGFDDIDIQDPPVGLTTIRQPTVLKGREAARALISGQLDNDISLDFELVVRDSA
>NZ_CP045145.1|WP_002210201.1|1864961_1866350_-|phosphomannomutase/phosphoglucomutase
MEKLTCFKAYDIRGKLGSELNEEIAYRIGRAYCQWLKPAKVVVGGDARATSVELKNALAKGLMDGGADVIDIGMVGTEEVYFATRFYGVDGGIQVTASHNPIDYNGMKLVKKDAQPISGDNGLYEIQRLAQDNHFAPPGVRGQLETQLVREHYVEHLLSYIDLNALLPMKIVVNAGNGAAGPTLDALEAALAKRKVPISFIKINHQPDSSFPNGIPNPMLPENQWSTRQAVCEHQADLGIAWDGDFDRCFFFDHLGNFIEGYYIVGLLAEKFLLTNNMGKATHNTDKIIHDPRLTWNTIDIVQTLNGTAIESKTGHAFIKDAMRHHDAVYGGEMSAHHYFREFGYCDSGMIPWLLVIELLSKKTTSLFSLIESRKAKFPVSGELNFTVSDPKTKIQQIKQFYADSAIHVTGIDGLSMEFEHWRFNLRSSNTEPLVRLNIETRGDVTLLEQKTAQLTQLLYPK
>NZ_CP045145.1|WP_002210191.1|1878463_1879444_+|type-I-F-CRISPR-associated-endonuclease-Cas1
MENAIHSSDLKTILHSKRSNIYYLEYCRVLVNGGRVEYVTDEGKQSLYWNIPIANTTVIMLGTGTSVTQAAMREFARAGVLVGFCGGGGTPLFAANDVEVNVSWLTAQSEYRPTEYLHDWVSFWFDDEKRLAAAVAFQRIRIAQIQQHWLSSHIQRESLFPVNHDQLLFILTRFEQNLANCLTSNDLMVQEAVLTKALYKLAANTVNYGDFTRAKRGGGIDLANRFLDHGNYLAYGLAATATWVIGLPHGLSVLHGKTRRGGLVFDVADLIKDALVLPQAFIAAMQGEEEQEFRQRCISGFQRTEALDVMIDGIKETAALCSQVPR
>NZ_CP045145.1|WP_002221142.1|1879440_1882728_+|type-I-F-CRISPR-associated-helicase-Cas3
MNILLISQCHKRALNETRRILDQFAERKGDRTWQTAITQEGLNTLRKLLRRTARRNSAVACHWIKSNNQSELLWIVGNLRRFNAEGTVPTNTTQRDILRSQDENNWHSVETIALLAGIAGLFHDFGKANVLFQQGLQGQGKTYQPYRHEWVSLRLFQAFVEQKNDIQWLTALSQINPADETTLMSNLVKDGLDDYTNPLAALPPLAKTIAWLILSHHRLPVYPSKDYHRPPKVEEIDDWLHQQLMPVWNSTNMDSGDWREKDKLDVWRFPHGTPLQSAEWCKKAQKFAKRALRQPSLVNDGHLNQRFTSHMARLVLMLADHHYSSLPATPGWQDKNYQVFANTHNKMRDANAHSKTIEMKQRLDEHNIGVGQNALLLGRSLPHIRKTLPAITRHKGFKQRSVQEKYRWQDKAFDLAVTLRERSLQQGFFGVNMASTGCGKTFANARIMYGLSDEKQGCRFSVALGLRTLTLQTGTALQQKLTLQKDDLAVLIGSQSVLQLYQLNNDKLEPRGTGSQSADKFFSEHQYVSYDGSLDDGRLSTWLSNNDRLKRLLCAPVLVCTIDHLIPATESLRGGKQIAPMLRLLTSDLVLDEPDDFDRNDLPALCRLVNWAGMLGSRVLLSSATLPPALVQALFNAYRAGRADYQQASGQPDTPVNICCAWFDEHGVAQQDIQQSKDFIQHHGDFITRRVGKLSTAEVLRRAELIPVSSASVKNGSVLDAMAAVMRDSMLRLHQAHHQTHPSEKTVSVGVVRMANIDPLVAIAQRLYAMAAPENYRIHYCVYHSQHPLAVRSAIERRLDVTLTRYQPNALWQVAEIEHALQHHPEQHHLFVVLATSVVEVGRDHDYDWALAEPSSMRSFIQLAGRVQRHRQVAPQMANMHILQKNFKALTQKDPAIPVYCKPGFETTRCRLNTHDLDKLLLPSQYKVINAISRIQERTKLEPRDNFVDLEHLSLRLILQGSAEPLKYYAALWWRKQATWSGEQQRCTPFRQSSPDEQHNLWIDDEADKPVFKRLDSDQIEWKVSDGFQDVELTLAAGNSAWIDTDCLRIYQWLAESLNKELNEVSRQFGEVRLPKKDGERWHYHPLLGVFGALD
>NZ_CP045145.1|WP_002222491.1|1883136_1884483_+|type-I-F-CRISPR-associated-protein-Csy1
MSDEGLAAFIVSYIKSREQPKLEAFDKEAEKRLAGLTQAEDIALAQQEIAQQRQELIARYEVRNWLTDAANRAGQIKLATHAPKYTHSDSKSSGILNIELQSKKKDYFSSVDLAEQASDVIGNAAVFDLVKLLQSECEGGSLIKCLEQGDNSVLKLFSNDDELVEEWTTKFKSILNNEKFTSHKLAKQFYFPVGPDQYHLLSPLFSSSLAQAMHQRIIEARFSDQSKEAKAAHKAGRWHPTVRVLYLDTAVQHIGGTKPQNISYLNSVRGGKVWLLPCGAPSWKNIQKPPIKYRSIFHDRSEFTVLARNNLWQMQLYLLGVKPLSNTMDIRAARLACCDEIIDILFNYVAEIQNLDGTNGWSDAEDCKLKRSEQLWLDPTRAMDDPVFKLEREKEDWKQEVSQDFGYWLNRWLQHDELVFGYVEQREWSSLFKQRLREFEQGSLETSS
>NZ_CP045145.1|WP_002211868.1|1884479_1885430_+|type-I-F-CRISPR-associated-protein-Csy2
MSSLIVLHQVRVENANAIAGLTYGFPAITHFLGYSHALSRKLQSSHGLTLRGCAVICHYQQVHAYLSGWDYVFSLTRNPLTKEAKTAAFNEEGRMHMTVSLVIECDGTIANGDDGANALEKHLASLCLTQRLAGGTITNIRRVKVINYPETEVATRRLLCRLLPGFALLDRSELLAEHLNRLRQTNPQAEMLDAWLDFSALKIQAIPPQSDTPVESGAPAPWGYVGKPAAGYLVPIVTGYRAISPLYAPGEVDKTRDPHTPFRFVESLYGIGEWRGLHRITDLRQLLWGYHQEGDNYLCRCALPASVDTYLLNDEE
>NZ_CP045145.1|WP_002211867.1|1885447_1886452_+|type-I-F-CRISPR-associated-protein-Csy3
MAKATIKTASVLAFERKLSNSDAMMYAGNWGQTDNWQPIIIKEKAVRGTISNRLKNALASDPAKLDAEIQKANLQRVDVAALPFDTDTLKMSFTLRVLGNLATPSVCNDQEYQAELASVINGYISEQSFSVLAARYAENLANGRFLWRNRVGAEDIKVCITSQTKSYQFDSNEFSLRQFSQPSKELTALAQEIEQGLAGNGFAFFTVDAFVRLGNGQEVFPSQELVLDSNSKKSKVLYQIDGIAALHSQKVGNALRTIDDWYPDATELALGPIAVEPYGSVTSRGKAYRQPKQKMDFYTLLDNWVTKGTVPAVEQQHYVMATLIRGGVFGEKGE
>NZ_CP045145.1|WP_002211866.1|1886462_1887017_+|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4
MDHYLDIRVLPDPEFSAQTLLEALFAKLHRALVATIPGRVGVSFPTAGKTLGSQLRLHGSRGDLLELQSAGWLKGLQDYCECSEILPVPADVKHRTIRRVQVKSSAQRLRRRSVSKGWLTEEQARLRIPDSHDKRCDLPFLRLKSRSSEQYFLLFIEQGTLQASATTGEFSAYGLSVNATIPWF
>NZ_CP045145.1|WP_002211865.1|1887094_1888114_-|aldo/keto-reductase
MDYIKLGHCGLQVSRLCLGTMNMGSKQWKPWVFDKAESTPLIKHALDCGINFIDLADFYSAGVGEEVVGRIVKNLMSRDELVLTTKVGYPIGHGPNNQGHSRKHIMASIDASLKRLGTDYIDIYMLHYFDINTPVEETWSAMNDIIHSGKARYTGVSTMFTWQLSKILWCCERNGFAKPINMQLQLNCAYREEEREMIPQCRDQGLGISAFSPLARGLLSCDFSSVRNKTDFFTQEMYADVTSLNIAQSVERVAKNRGITPAQVAQAWVLNHPGTDCMLVGADTIEQINSAVTALRISLNAEEHFELERNYTPCDVINDYTAGQRIAREARPPSGIFAP
>NZ_CP045145.1|WP_002211864.1|1888124_1888628_-|formaldehyde-activating-enzyme
MQMYIGEGFAGNGVNAAHINIMIGPRDGVVGQAFAASLASPSQGHYPFIVVIKPNVAAKPMTLYVNKAEIRSELHGRATWGASQAAVAKAVAEALLANLFPPEAEDDWCIITANWVNIDCDDIDEVYRNNYRACTTALHAAMAKTPKRDQLTHALTQLSNPFFTPKA
>NZ_CP045145.1|WP_002211863.1|1888674_1890033_-|MFS-transporter
MQTLPSEKIRMDDVPLNRFHIRIAGLTFGAHFIDGYILGLIGFALIQLKPIMALTPLWEGLLGSAALIGLFLGSLILGWISDYIGRQKIFSFSFVIITLASALQFFASTPEQLFILRVIVGIGIGGDYSVGHTLLAEFSPRKHRGVLLGAFSVIWTFGYVSASFVGHYLSMVSPEAWRWLLSSAALPALLILLVRIGTPESPRWLMGKGREDDAMAIVHKYFGPNVTLIDEEPATSTRRFLSLFGRKYWRRTAFNSLFFVCLVIPYFAIYTFLPSILNVMALSQNFATDLLLNGLLVVGALVGIVLTAFCSRRSFLISSFIFLATCLLLLSILPSNQTFWLIALFAAFTLVMSAVSNLVGVFPAESFPTEVRSMGVGFATSMSRLGSAIGTSLLPLAIVNYGMPVTTTLLAFVLIIGAIVSIAWAPETKGLTLVDASQSATTPRPPSSIIPN
>NZ_CP045145.1|WP_002216551.1|1890156_1890366_+|hypothetical-protein
MVIGDLLTETDRLFQKRTAAMDDLFSSPGPVRLILFVMAMCQPKYKAASAFYAYPSEKKVRDPPLNSYK

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Crispr_ID: NZ_CP045145_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045145_4

2857303-2857512

Orphan

I-F

Consensus_repeat	Method
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	CRISPRCasFinder
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	CRT
AGGTTCACTGCCGCACAGGCAGCTTAGAAAAT	PILER-CR

3 spacers

DEDDh

The CRISPR arrays of NZ_CP045145_4

>merge|NZ_CP045145|4|2857303-2857512|CRISPRCasFinder,CRT,PILER-CR
TTATTGGGCTGCCTGTGCGGCAGTGAACGTTATACCCCGCGCAGGGAGTGAAGCGTTGACTTTCTAAGCTGCCTGTGCGGCAGTGAACTTAAGTTCTTTTTGTCAGCATCTTTAATAAATTTTCTAAGCTGCCTGTGCGGCAGTGAACCTGAAATACAAATAAAATAAATCGTCGAACATTTTCTAAGCTGCCTGTGCGGCAGTGAACGT

>NZ_CP045145|4|3|2857303-2857510|CRISPRCasFinder
TTATTGGGCTGCCTGTGCGGCAGTGAAC	GTTATACCCCGCGCAGGGAGTGAAGCGTTGAC
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	TTAAGTTCTTTTTGTCAGCATCTTTAATAAAT
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	CTGAAATACAAATAAAATAAATCGTCGAACAT
TTTCTAAGCTGCCTGTGCGGCAGTGAAC

>NZ_CP045145|4|3|2857303-2857510|CRT
TTATTGGGCTGCCTGTGCGGCAGTGAAC	GTTATACCCCGCGCAGGGAGTGAAGCGTTGAC
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	TTAAGTTCTTTTTGTCAGCATCTTTAATAAAT
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	CTGAAATACAAATAAAATAAATCGTCGAACAT
TTTCTAAGCTGCCTGTGCGGCAGTGAAC

>NZ_CP045145|4|4|2857363-2857512|PILER-CR
TTTCTAAGCTGCCTGTGCGGCAGTGAACTTAA	GTTCTTTTTGTCAGCATCTTTAATAAAT
TTTCTAAGCTGCCTGTGCGGCAGTGAACCTGA	AATACAAATAAAATAAATCGTCGAACAT
TTTCTAAGCTGCCTGTGCGGCAGTGAACGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045145.1\|WP_002216393.1\|2845062_2845803_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187626
NZ_CP045145.1\|WP_002211902.1\|2858004_2859396_-\|APC-family-permease	unknown	unknown	gnl\|CDD\|223605
NZ_CP045145.1\|WP_002216388.1\|2848990_2852143_+\|inverse-autotransporter-beta-barrel-domain-containing-protein	unknown	unknown	gnl\|CDD\|378762
NZ_CP045145.1\|WP_002209743.1\|2852105_2853314_-\|IS256-family-transposase	unknown	unknown	gnl\|CDD\|225865
NZ_CP045145.1\|WP_002211911.1\|2846661_2847966_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340877
NZ_CP045145.1\|WP_002211905.1\|2854435_2855545_-\|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl\|CDD\|187547
NZ_CP045145.1\|WP_002211916.1\|2844172_2845015_-\|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
NZ_CP045145.1\|WP_002211896.1\|2866131_2867031_+\|ATP-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|234781
NZ_CP045145.1\|WP_002211904.1\|2855837_2857268_+\|exodeoxyribonuclease-I	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|236979
NZ_CP045145.1\|WP_002231208.1\|2865801_2865849_+\|his-operon-leader-peptide	unknown	unknown	unknown
NZ_CP045145.1\|WP_002211900.1\|2862769_2863765_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224093
NZ_CP045145.1\|WP_002216311.1\|2861232_2862126_+\|sugar-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224053
NZ_CP045145.1\|WP_002211917.1\|2842863_2844141_-\|L-fuconate-dehydratase	unknown	unknown	gnl\|CDD\|239440
NZ_CP045145.1\|WP_002216312.1\|2859855_2860947_-\|oxidoreductase	unknown	unknown	gnl\|CDD\|182570
NZ_CP045145.1\|WP_002211912.1\|2846230_2846653_+\|thiol-disulfide-oxidoreductase-DCC-family-protein	unknown	unknown	gnl\|CDD\|225556
NZ_CP045145.1\|WP_002216310.1\|2862083_2862773_+\|sugar-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224053
NZ_CP045145.1\|WP_002211895.1\|2867034_2868366_+\|histidinol-dehydrogenase	unknown	unknown	gnl\|CDD\|234853
NZ_CP045145.1\|WP_157131899.1\|2864153_2864444_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|374732
NZ_CP045145.1\|WP_002211898.1\|2864598_2865426_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187576
NZ_CP045145.1\|WP_002217522.1\|2853684_2854002_-\|DUF496-family-protein	unknown	unknown	gnl\|CDD\|180070

Protein	Function_ID	Function_description	E-value
NZ_CP045145.1\|WP_002216393.1\|2845062_2845803_-\|SDR-family-oxidoreductase	gnl\|CDD\|187626	cd05368, DHRS6_like_SDR_c, human DHRS6-like, classical (c) SDRs. Human DHRS6, and similar proteins. These proteins are classical SDRs, with a canonical active site tetrad and a close match to the typical Gly-rich NAD-binding motif. Human DHRS6 is a cytosolic type 2 (R)-hydroxybutyrate dehydrogenase, which catalyses the conversion of (R)-hydroxybutyrate to acetoacetate. Also included in this subgroup is Escherichia coli UcpA (upstream cys P). Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction. Note: removed : needed to make this chiodl smaller when drew final trees: rmeoved text form description: Other proteins in this subgroup include Thermoplasma acidophilum aldohexose dehydrogenase, which has high dehydrogenase activity against D-mannose, Bacillus subtilis BacC involved in the biosynthesis of the dipeptide bacilysin and its antibiotic moiety anticapsin, Sphingomonas paucimobilis strain B90 LinC, involved in the degradation of hexachlorocyclohexane isomers...... P).	1.05065e-117
NZ_CP045145.1\|WP_002211902.1\|2858004_2859396_-\|APC-family-permease	gnl\|CDD\|223605	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism].	3.72025e-45
NZ_CP045145.1\|WP_002216388.1\|2848990_2852143_+\|inverse-autotransporter-beta-barrel-domain-containing-protein	gnl\|CDD\|378762	pfam11924, IAT_beta, Inverse autotransporter, beta-domain. This is a family of beta-barrel porin-like outer membrane proteins from enteropathogenic Gram-negative bacteria. Intimins and invasins are virulence factors produced by pathogenic Gram-negative bacteria. They carry C-terminal extracellular passenger domains that are involved in adhesion to host cells and N-terminal beta domains that are embedded in the outer membrane. This family represents the beta-barrel porin-like domain in the outer membrane that can be found in intimins, invasins and some inverse autotransporters.	1.47456e-126
NZ_CP045145.1\|WP_002209743.1\|2852105_2853314_-\|IS256-family-transposase	gnl\|CDD\|225865	COG3328, COG3328, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.39969e-152
NZ_CP045145.1\|WP_002211911.1\|2846661_2847966_-\|MFS-transporter	gnl\|CDD\|340877	cd17319, MFS_ExuT_GudP_like, Hexuronate transporter, Glucarate transporter, and similar transporters of the Major Facilitator Superfamily. This family is composed of predominantly bacterial transporters for hexuronate (ExuT), glucarate (GudP), galactarate (GarP), and galactonate (DgoT). They mediate the uptake of these compounds into the cell. They belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.17308e-74
NZ_CP045145.1\|WP_002211905.1\|2854435_2855545_-\|NAD-dependent-epimerase/dehydratase-family-protein	gnl\|CDD\|187547	cd05236, FAR-N_SDR_e, fatty acyl CoA reductases (FARs), extended (e) SDRs. SDRs are Rossmann-fold NAD(P)H-binding proteins, many of which may function as fatty acyl CoA reductases (FAR), acting on medium and long chain fatty acids, and have been reported to be involved in diverse processes such as biosynthesis of insect pheromones, plant cuticular wax production, and mammalian wax biosynthesis. In Arabidopsis thaliana, proteins with this particular architecture have also been identified as the MALE STERILITY 2 (MS2) gene product, which is implicated in male gametogenesis. Mutations in MS2 inhibit the synthesis of exine (sporopollenin), rendering plants unable to reduce pollen wall fatty acids to corresponding alcohols. This N-terminal domain shares the catalytic triad (but not the upstream Asn) and characteristic NADP-binding motif of the extended SDR family. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.89947e-61
NZ_CP045145.1\|WP_002211916.1\|2844172_2845015_-\|fumarylacetoacetate-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	8.96038e-107
NZ_CP045145.1\|WP_002211896.1\|2866131_2867031_+\|ATP-phosphoribosyltransferase	gnl\|CDD\|234781	PRK00489, hisG, ATP phosphoribosyltransferase; Reviewed.	6.63843e-161
NZ_CP045145.1\|WP_002211904.1\|2855837_2857268_+\|exodeoxyribonuclease-I	gnl\|CDD\|236979	PRK11779, sbcB, exonuclease I; Provisional.	0
NZ_CP045145.1\|WP_002211900.1\|2862769_2863765_+\|ABC-transporter-permease	gnl\|CDD\|224093	COG1172, AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism].	1.22935e-72
NZ_CP045145.1\|WP_002216311.1\|2861232_2862126_+\|sugar-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	3.90601e-98
NZ_CP045145.1\|WP_002211917.1\|2842863_2844141_-\|L-fuconate-dehydratase	gnl\|CDD\|239440	cd03324, rTSbeta_L-fuconate_dehydratase, Human rTS beta is encoded by the rTS gene which, through alternative RNA splicing, also encodes rTS alpha whose mRNA is complementary to thymidylate synthase mRNA. rTS beta expression is associated with the production of small molecules that appear to mediate the down-regulation of thymidylate synthase protein by a novel intercellular signaling mechanism. A member of this family, from Xanthomonas, has been characterized to be a L-fuconate dehydratase. rTS beta belongs to the enolase superfamily of enzymes, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion.	0
NZ_CP045145.1\|WP_002216312.1\|2859855_2860947_-\|oxidoreductase	gnl\|CDD\|182570	PRK10586, PRK10586, putative oxidoreductase; Provisional.	0
NZ_CP045145.1\|WP_002211912.1\|2846230_2846653_+\|thiol-disulfide-oxidoreductase-DCC-family-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	5.0494e-57
NZ_CP045145.1\|WP_002216310.1\|2862083_2862773_+\|sugar-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	1.76633e-90
NZ_CP045145.1\|WP_002211895.1\|2867034_2868366_+\|histidinol-dehydrogenase	gnl\|CDD\|234853	PRK00877, hisD, bifunctional histidinal dehydrogenase/ histidinol dehydrogenase; Reviewed.	0
NZ_CP045145.1\|WP_157131899.1\|2864153_2864444_+\|hypothetical-protein	gnl\|CDD\|374732	pfam16695, Tai4, Type VI secretion system (T6SS), amidase immunity protein. Tai4 is a new form of autoimmunity protein for a type VI secretion system, T6SS. T6SS has roles in interspecies interactions, as well as higher order host-infection, by injecting effector proteins into the periplasmic compartment of the recipient cells of closely related species. Pseudomonas aeruginosa produces at least three effector proteins to other cells and thus has three specific cognate immunity proteins to protect itself. Tae4, or type VI amidase effector 4, in Enterobacter cloacae has a cognate Tai4 or type VI amidase immunity 4 protein. The effector is Tae4, pfam14113.	4.0065e-14
NZ_CP045145.1\|WP_002211898.1\|2864598_2865426_-\|SDR-family-oxidoreductase	gnl\|CDD\|187576	cd05266, SDR_a4, atypical (a) SDRs, subgroup 4. Atypical SDRs in this subgroup are poorly defined, one member is identified as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is related to, but is different from, the archetypical SDRs, GXGXXG. This subgroup also lacks most of the characteristic active site residues of the SDRs; however, the upstream Ser is present at the usual place, and some potential catalytic residues are present in place of the usual YXXXK active site motif. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	2.54107e-68
NZ_CP045145.1\|WP_002217522.1\|2853684_2854002_-\|DUF496-family-protein	gnl\|CDD\|180070	PRK05423, PRK05423, DUF496 family protein.	5.26004e-59

>NZ_CP045145.1|WP_002211904.1|2855837_2857268_+|exodeoxyribonuclease-I
MSDKNKQPTFYVHDYETFGQRPALDRPAQFAGVRTDLDFNLVEEPLVIYCKPADDYLPQPEAVMITGITPQHALANGVNEAEFSRQIHQAFSVPGTCILGYNNIRFDDEVSRNIFYRNFYDPYAYSWQGGNSRWDLLDVMRACYALRPEGIVWPENDDGLPSFKLEHLTKANGVEHLQAHDAMSDVYATIAMAKLVKQAQPRLFDYLYQHRSKHKINALIDIAEMTPLVHVSGMFGAARGNTSWVAPLAWHPENKNAVIMCDLAGDMSPLLELDSDTLRERLYTRRDKLQAQESAIPIKLVHINKCPVLAPAKTLLPENADRLGIDRQRCLQNLQLLRQNPQVREKVVALFAQAEPFAVTDDVDTQLYNGFFSDADRATIKIIQQTESQNLPALDLTFQDPRLEALLFRFRARNYPNTLNDSEQQRWLQHRREALSPERVQDYVLQLEQFYNQYEDDKEKLALLKALFEYAKGLVS
>NZ_CP045145.1|WP_002211905.1|2854435_2855545_-|NAD-dependent-epimerase/dehydratase-family-protein
MKKLLLTGATGFLGGAVLEKLLLASSDFNYLLLVRANTPEQGLMRIRENLEKFYLPNELINKININHVLLGDLAEPDSFINDVRIDDVTHVINCAAIASFGNNPLIWKVNVEGTLAFGKRMAQVAGLQRFVHVGTAMACTPEADTVVDERVLSTENDAHLVEYTKSKSAIECLLAEHCPTLPLVFARPSIVVGHTRLGCQPSSSIFWVFRMALMLRKFMCSLDDHIDVIPVDYCADALLYILEYPNLPDDIYHISAGEKGSVSFSEIDQAMSVAAKQKPVGVNYSQVEYTALVQMRNQLKGIFGPCNERLMLKAMRLYGSFAMLNVRFSNERLLSLGMPRTPRFTDYIARCVESSHGMTIQQQMAVDFK
>NZ_CP045145.1|WP_002217522.1|2853684_2854002_-|DUF496-family-protein
MDNASKPTFQDVLEFVRMFRRKNKLQREIVDNEKKIRDNQKRVLLLDNLSEYIKPGMSIEEVQAIIANMRGDYEDRVDDYIIKNADLSKERRELSKKLKAMGEVK
>NZ_CP045145.1|WP_002209743.1|2852105_2853314_-|IS256-family-transposase
MDEKKLKALAAELAKGLKTEADLNAFSRMLTKLTVETALNAELTEHLGHEKNTPKSGSNTRNGYSSKTLLCDDGEIELNTPRDRENTFEPQLIKKNQTRITQMDSQILSLYAKGMTTREIVATFKEMYDADVSPTLISKVTDAVKEQVAEWQNRQLDALYPIVYMDCIVVKVRQNGSVINKAVFLALGINTEGQKELLGMWLAENEGAKFWLSVLTELKNRGLQDILIACVDGLKGFPDAINSVYPQTHIQLCIIHMVRNSLKYVSWKDYKAVTSGLKMVYQAPTEEAALMALDKFAEAWDDKYPQISKSWRTHWENLNTFFGYPPDIRKAIYTTNAIESVNSVIRAAIKKRKVFPTDDSVRKVVYLAIKDASKKWSMPIQNWRLAMSRFIIEFGDRLSDHL
>NZ_CP045145.1|WP_002216388.1|2848990_2852143_+|inverse-autotransporter-beta-barrel-domain-containing-protein
MSLYRISSLHQAKQLNKNKQLNKTRISKSVVWANIVIQAIFPLSIAFTPAVMAAETVGASDEKPRSASQAEQSTANAATRLASILTNDDSAKQASSIARGTAANAGNEALQKWFNQFGSAKVQLNLDEKLSLKGSQLDVLLPLTDSPDLLTFTQLGGRYIDDRVTLNVGLGQRHFFAQQMLGYNLFIDHDASYSHTRIGVGAEYGRDFINLAANGYFGVSGWKNSPDLDKYDEKVANGFDLRSEAYLPTLPQLGGKLIYEQYFGDEVGLFGVDNRQKNPLAVTLGVNYTPIPLFTVGVDHKMGRAGMNDTRFNLGFNYAFGTPLTHQLDSDAVAIKRSLMGSRYNLVDRNNQIVMKYRKQNRVTLELPARVSGAARQTMPLVANATAQQGIDRLEWEASALTLAGGKITGSGNNWQITLPSYLSGGEGNNTYRISAIAYDTLGNASPVAYSDLVVDSHGVNTNASGLTAAPEILPANASASSVIEFNIKDNANQPITGIADELAFSLELVELPEELAKAKARSVPLKTVSHTLTKITESAPGIYQATLTSGSKPQLINITAQINGVPLADVQTKVTLIADESTATLQTSSLQIITNGSLADDTDANQIRAVVVDAYGNKLSGVQVNFTVGNNAKITETTLSDKQGGVTAAITSTKAGTYTVTAELNGVTQQIDVNFIPDAGTATLDDSDEYKLQWVTNGQVADGESTNSVQLTVVDKFGNTVPGVDVAFTTDIGAIISEVTPTDANGVATAKIISSQAKSHTVKATLNRKEQTVEVNFIADTATAEITANNFTVEVDGQVAGSGTNQVQALVVDKKGNPVANMTVNFTATNGVVVETTSAKTDENGKVTTNLSMTNVGGTISTVTATMINSANVTSTQDKPVIFYPDFTKATLNTPANTYSGFNINSGFPTTGFKNTHFQLSPHGITGANSDYDWVSSHPNVSVSNTGAITLQDNPGGKVTITATWKHDSSKVFTYDFTLNYWVGLYSSTNLSWAQANASCINAGMRLPTNREVSAGQDVRGVGSLLSLSIILCNCHRIKGDRSGGHRTR
>NZ_CP045145.1|WP_002211911.1|2846661_2847966_-|MFS-transporter
MSNFNHYPDPTLNSAIKKAWYRLMPLMFIMYFVAFIDRINVGFAKDAMSADIGLSQSAFALGAGIFFAAYALFGIPANLMMNKLGAKVWLSSTTVVWGLLSAGTGLVSNEYQFVILRFLLGVAEAGFYPGILLLASIYFPNKIRASVIGIFVLGVPAALTLGSPISGALLDMQGFLGQPGWFWMFLLEGLPAVGLGIFAFFYLDDSPATARYLNPEEKQALLTQLSIEQSDTESSSVKAVLLSPKVWHLALIYGTIQVGVYGLIFFLPSQVATLLGSTLGFKESLVAAIPWAFSALGVYYIPRYADRKTHRRNPIATLNLVVAAIGLIISAYASPVLAIAALCLCAIGFLAVQPIFWTFPAQILSGKALAAGIGFCTTMGAFFSFLAPIIRVEAESQFNSPPAGLITLALFSLLSATLIFSLKFWPAKATAEVI
>NZ_CP045145.1|WP_002211912.1|2846230_2846653_+|thiol-disulfide-oxidoreductase-DCC-family-protein
MSAPLPYIKPGERVIIYDGVCALCTGWVNFLIRHDRRHTVRLSAVQSKKGHALLEWAGLPTDKINTLVLIENQQVYLRSEAIFRVIANLPWPWRILGVLRIFPRPLRDRCYDGIALNRYRLFGRYDAVRKLKADHERRFL
>NZ_CP045145.1|WP_002216393.1|2845062_2845803_-|SDR-family-oxidoreductase
MNLKGKKALVTAAGQGIGFNTATLFARKGAEVIASDINIAALSNIPGITAVSLDVTDTLAINDVAQAIGPIDVLFNCAGVVHSGDILTCSEQEWQFALDLNVTAMFHMIRAFLPGMIACQQGSIINMSSVASSIKGVPNRFAYSTSKAAVIGLTRSVAADYVTQGIRCNAICPGTVESPSLRQRIAVQAHAEGRSEADVFQAFAARQPIGRIGKAEEIAQLALYLASDASAYTTGTIHIIDGGWSN
>NZ_CP045145.1|WP_002211916.1|2844172_2845015_-|fumarylacetoacetate-hydrolase-family-protein
MKLLRYGPVGEERPALLDELGEIRDLSAHIEDISGKFLLPATLYKLRQLDSASLPLVRGEQRLGACVGHVGKFICVGLNYADHAAETGAEIPQEPVIFNKWTSAIIGPNDDIEIPRNSVKTDWEVELGVVIGTGGRYIGEANAMSYVAGYCVVNDISEREFQLEHGGTWDKGKGCDTFGPIGPWLVTRDEIPDPHQLGLWLDVDGRRYQNGSTRTMIFKIPQIISYLSRFMSLQSGDVISTGTPPGVGLGQKPPVYLHAGQIMRLGIEGLGEQCQKTIQA
>NZ_CP045145.1|WP_002211917.1|2842863_2844141_-|L-fuconate-dehydratase
MTIITALRTEDVRFPTSLELDGSDAMNPDPDYSAAYVILDTDNPALSGHGLTFTIGRGNEICCVAIHALEHLIVGRDLASMTANMGKFWREFTSDSQLRWIGPEKGAIHLATGAVINAVWDLWSKAEGKPLWRLVADMSPEELVRCIDFRYITDCITPEEALTLLQQRAHNKALRLEKLQDEGYPCYTTSAGWLGYPDDKLRRLCQDAVDAGFDYLKLKVGRDLEDDIRRVRITREVLGPDRKLMIDANQIWETNEAIPWVNQLAFANPWFIEEPTNPDDIEGHRRIRQGVAPVKVATGEMCQNRIMFKQFIMREAIDVVQIDACRLGGVNEVLAVMLMAAKYDLPVCPHAGGVGLCEYVQHLAMIDYLCIAGTDKGRVIEYVDHLHEHFVHPCVIKNAAYMPPEQPGFSIEMHQSSIEKYRFRV
>NZ_CP045145.1|WP_002211902.1|2858004_2859396_-|APC-family-permease
MAHDATVAVGTNQTGTNNRVQLRKTLTLVQVVMMGLAYLQPMTIFDTFGIVSGLTDGHVATSYAIALIAVLFTAVSYGKLVKRFPSAGSAYTYAQKSISPNVGFMVGWSSLLDYLFMPMINILLAKIYLEAIFPGVPSWIFVGALVSLMTLFNLRGINIVANLNSVIVVVQVAIMVVFMGLLIHGVYQGEGAGTLVSARPFYSENAHLVPMITGATILCFSFLGFDGISSLSEETPNAGKVIPKAIFLTALIGGIIFIAVSYCLQLYFPDISRFTDPEASQPEIMLFVAGKFFQSVILCFSCVTVLASGMAAHAGVSRLLYVMGRDGVFPEKVFGYVHPKWRTPAINVLLVGGVALSAISFDLVTATALINFGALVAFTFVNLSVIAQFYVRERRNSTFKDHFNYLILPMIGAGTVGVLWVNLESSSMTLGLVWGAIGLSYMVWKTRAFRRALPQFTEEPAQL
>NZ_CP045145.1|WP_002216312.1|2859855_2860947_-|oxidoreductase
MSANAIRVQVGPANYFSFPGAIDKLSEFYPQAALDKALWIYGERALAAAQDYLPKAFHGPQAVRAKFSTHCSQSTVADLVSAAGGDRQVVIGIGGGAVLDTAKVVARQLGVPLVAIPTIAATCAAWTPLSVWYNEAGQALNFEIFNDANHLVLVEPRIMLHAPVEYLLAGIGDTLAKWYEAVVLSPQPETLSLTVRLGLQAALEIRNVLLKQSEAALQAVAQGELTQDFLDVVDAIIAGGGMVGGLGERYTRVAAAHAVHNGLTLLPQTEHFLHGTKVAYGILVQTALLGQDEVLRSLIVAFNQLGLPTHLAALDVDINDREAIDRVIGRILKPGESIHYLPIALNSEKVWAAIEQVEIAAQH
>NZ_CP045145.1|WP_002216311.1|2861232_2862126_+|sugar-ABC-transporter-ATP-binding-protein
MSSIPPSRLEMRNISISFSGFHALQEVDFTLEGGSTHALIGANGAGKSTLMAILSGAHNHYRGEIFIDGQPIDIHSPRQARQHGIHVVQQEVDVALIPTLSVAENIMLDELADRGHLFNWPQLYRQAEALLEQLELKLNVRQRLESCTLAEKQQVLLARALSHQCRFLILDEPTAPLDQEESARLFRVVRRLQSEGIGIVFISHRIHELREVCDQLTVLRDGRRVSHDTMEGMSGEQIVEKMLGHTLEDISPLGERQSAAKHGCRKHYCRKHCYRSAAYMISISCAISPSHYIRAKF
>NZ_CP045145.1|WP_002216310.1|2862083_2862773_+|sugar-ABC-transporter-ATP-binding-protein
MRDISLTLHQGEILGIAGLAGAGKTELCKALFGDTPSTLERGELSGKAWRPRSPDRSVAQGLALVPEERRKEGIFIDEGIPMNLSVAADDSFSRWSLFSRRQELSWAKELIERLGIRTSSPQQKLAHLSGGNQQKVAIGKWLRGDAQVLIFDEPTKGVDIKAKQDLFSLIDQLAQQGKGIIYASGEFSELVGLCDRICVLWDGRIVAELNAAEVDEETLLLFSTGGTPQ
>NZ_CP045145.1|WP_002211900.1|2862769_2863765_+|ABC-transporter-permease
MSKELPLPDVQPWRHQLFDFLYKWGMLLTVVALIALFGLASDNFLDPNNIINILRSIAIVTVIAIGVSISLSIGGFDLSVGSTASLANAVVVSLFVWYGFGTTGAIILTLLICTLVGLFNAFLIVVLKIPDMLATLASLFVIQGVAMTYSRGGSITQSMLLPSGDMAEGVIPEIFSALGQVPVIVLIMLAVTVVVQLYLSLTKHGRRMYAIGGNPQAARLAGIRTVRYRVLAYVLSAQLAALGGILLASRIGSSQVNAGSGYLMDAVAAAYIGFSLAGSGKPNAFGTLIGAIILGVLQNGLVMLSVPYYAMDIIKGLVLAMALALTYIQKR
>NZ_CP045145.1|WP_157131899.1|2864153_2864444_+|hypothetical-protein
MQQKNNLENFALSICLAEGFPDGEINSEAFSAVGAYVELGAYPVEAYEEVSELAKKFLEKKYISKNGESKLTVMKCIDLSQSSELSAIKDKYTRHI
>NZ_CP045145.1|WP_002211898.1|2864598_2865426_-|SDR-family-oxidoreductase
MKKVAIIGLGWLGMPLAQSLSRRGIDVVGSKTTPDGVDAARMSGINCYPLVLTPELICEPDDLAQLMAVDALVITLPASRTTAGGDHYFQAVQQVVDSALAFGVPRIIFTSSTSVYGETRGRIKESSPLQPVTVAGKTLMALEQWLHQLPHTSVDILRLAGLVGTDRHPGRFLAGKTGVKGGSQGVNLVHQEDVIAAIELLLNRPKGGHLYNLCAPIHPRKRDFYPACARALQLTPPEFAVEEQEGANREIDGSKICSELGFEYLYPDPSRMPLN
>NZ_CP045145.1|WP_002231208.1|2865801_2865849_+|his-operon-leader-peptide
MNRVQFNHHHHHHPD
>NZ_CP045145.1|WP_002211896.1|2866131_2867031_+|ATP-phosphoribosyltransferase
MLDKTRLRIAMQKSGRLSDESQELLSRCGIKINLQQQRLIAFAENMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGDDPRYFTLRRLDFGGCRLSLAAPLDAEYTGPQCLQDTRIATSYPHILKQYLDKQGVRFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMSVDKQQLIDRLMTRIQGVIQARESKYIMMHAPSERLDEIITLLPGAERPTILPLAGDKSRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME
>NZ_CP045145.1|WP_002211895.1|2867034_2868366_+|histidinol-dehydrogenase
MQPTNFNTLINWQQCSEEQQKALLSRPAINASERITAAVSDILDRVKAEGDSALRDFSQRFDHVQVADIRITASEIAAASARLSDDVKHAMAQAVRNIEIFHNAQKMPVVDVETQPGVRCQQITRPIASVGLYIPGGSAPLPSTVLMLGTPARIAGCQRVVLCSPPPIADEILYAAQLCGIQEVFQIGGAQAIAAMAFGSESVPKVHKIFGPGNAYVTEAKRQVSQRLDGAAIDMPAGPSEVLVIADSGATPAFIAADLLSQAEHGPDSQVILLTPDAAIAQAVAVEVEQQLALLSRADIARQALESSRLIVTNDLQQCIDISNAYGPEHLILQIRQPEEIIDQIDNAGSVFMGDWSPESAGDYASGTNHVLPTYGYTSTYSSLGLADFVKRMTVQQLTPQGLLGLASTIETLAQAEQLTAHKNAVTLRVTALNNALTAVNKE

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Crispr_ID: NZ_CP045145_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045145_5

2982460-2982581

Orphan

Consensus_repeat	Method
CAATTGATTATATCGATTAATATTGGCATTAAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045145_5

>merge|NZ_CP045145|5|2982460-2982581|CRISPRCasFinder
CAATTGATTATATCGATTAATATTGGCATTAAGAGATTTAATACTGCAATATGTTTTTTTGGAAAAAACTCAATCCTCCCCCTCCACTACAATTGATTATGTCGATTAATATTGGCATTAAG

>NZ_CP045145|5|4|2982460-2982581|CRISPRCasFinder
CAATTGATTATATCGATTAATATTGGCATTAAG	AGATTTAATACTGCAATATGTTTTTTTGGAAAAAACTCAATCCTCCCCCTCCACTA
CAATTGATTATGTCGATTAATATTGGCATTAAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045145.1\|WP_002213039.1\|2983733_2986151_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366708
NZ_CP045145.1\|WP_002213036.1\|2981884_2982103_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045145.1\|WP_002213056.1\|2992226_2992643_-\|CoA-binding-protein	unknown	unknown	gnl\|CDD\|224745
NZ_CP045145.1\|WP_002213049.1\|2990177_2990456_-\|acylphosphatase	unknown	unknown	gnl\|CDD\|184675
NZ_CP045145.1\|WP_002213046.1\|2989796_2990126_+\|sulfurtransferase-TusE	unknown	unknown	gnl\|CDD\|225472
NZ_CP045145.1\|WP_002228570.1\|2975046_2975487_-\|lipocalin-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|372819
NZ_CP045145.1\|WP_002213028.1\|2977830_2979069_-\|hydroxymethylglutaryl-CoA-synthase-family-protein	unknown	unknown	gnl\|CDD\|225959
NZ_CP045145.1\|WP_002213052.1\|2990549_2991740_+\|23S-rRNA-(cytosine(1962)-C(5))-methyltransferase-RlmI	unknown	unknown	gnl\|CDD\|185082
NZ_CP045145.1\|WP_002213026.1\|2977118_2977838_-\|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl\|CDD\|223955
NZ_CP045145.1\|WP_002213017.1\|2974760_2975009_-\|acyl-carrier-protein	unknown	unknown	gnl\|CDD\|180851
NZ_CP045145.1\|WP_002213060.1\|2993817_2994282_+\|methylglyoxal-synthase	unknown	unknown	gnl\|CDD\|179969
NZ_CP045145.1\|WP_002213034.1\|2981096_2981621_-\|beta-hydroxyacyl-ACP-dehydratase	unknown	unknown	gnl\|CDD\|223835
NZ_CP045145.1\|WP_002213058.1\|2992958_2993639_+\|DUF2057-family-protein	unknown	unknown	gnl\|CDD\|179619
NZ_CP045145.1\|WP_002213054.1\|2991800_2992118_+\|heat-shock-protein-HspQ	unknown	unknown	gnl\|CDD\|184526
NZ_CP045145.1\|WP_002213024.1\|2975573_2976362_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|212491
NZ_CP045145.1\|WP_002213032.1\|2979823_2981107_-\|beta-ketoacyl-[acyl-carrier-protein]-synthase-family-protein	unknown	unknown	gnl\|CDD\|238430
NZ_CP045145.1\|WP_002213030.1\|2979084_2979822_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187594
NZ_CP045145.1\|WP_002213025.1\|2976364_2977117_-\|enoyl-CoA-hydratase	unknown	unknown	gnl\|CDD\|235936
NZ_CP045145.1\|WP_002221095.1\|2994342_2996397_-\|DNA-helicase-IV	unknown	unknown	gnl\|CDD\|182930
NZ_CP045145.1\|WP_002213038.1\|2982833_2983580_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|180440

Protein	Function_ID	Function_description	E-value
NZ_CP045145.1\|WP_002213039.1\|2983733_2986151_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366708	pfam01565, FAD_binding_4, FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidizes the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan.	1.41205e-31
NZ_CP045145.1\|WP_002213046.1\|2989796_2990126_+\|sulfurtransferase-TusE	gnl\|CDD\|225472	COG2920, DsrC, Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism].	2.4785e-71
NZ_CP045145.1\|WP_002213056.1\|2992226_2992643_-\|CoA-binding-protein	gnl\|CDD\|224745	COG1832, COG1832, Predicted CoA-binding protein [General function prediction only].	1.53332e-71
NZ_CP045145.1\|WP_002213049.1\|2990177_2990456_-\|acylphosphatase	gnl\|CDD\|184675	PRK14426, PRK14426, acylphosphatase; Provisional.	1.02172e-54
NZ_CP045145.1\|WP_002228570.1\|2975046_2975487_-\|lipocalin-like-domain-containing-protein	gnl\|CDD\|372819	pfam13924, Lipocalin_5, Lipocalin-like domain. This family includes domains distantly related to lipocalins. However, they do contain the important GXW motif in the first strand. The protein in this family include aln5, which is involved in biosynthesis of alnumycin. The family also includes the ZFK protein from Trypanosoma brucei which is a protein kinase. This domain is at the C-terminus of that protein. The domain is also found as the C-terminal domain in StiJ a protein involved in producing stigmatellin. This domain has been assumed to catalyze a final cyclisation reaction.	5.67247e-46
NZ_CP045145.1\|WP_002213028.1\|2977830_2979069_-\|hydroxymethylglutaryl-CoA-synthase-family-protein	gnl\|CDD\|225959	COG3425, PksG, 3-hydroxy-3-methylglutaryl CoA synthase [Lipid metabolism].	1.57028e-141
NZ_CP045145.1\|WP_002213052.1\|2990549_2991740_+\|23S-rRNA-(cytosine(1962)-C(5))-methyltransferase-RlmI	gnl\|CDD\|185082	PRK15128, PRK15128, 23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI.	0
NZ_CP045145.1\|WP_002213026.1\|2977118_2977838_-\|enoyl-CoA-hydratase/isomerase-family-protein	gnl\|CDD\|223955	COG1024, CaiD, Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism].	1.17502e-35
NZ_CP045145.1\|WP_002213017.1\|2974760_2975009_-\|acyl-carrier-protein	gnl\|CDD\|180851	PRK07117, PRK07117, acyl carrier protein; Validated.	4.77778e-09
NZ_CP045145.1\|WP_002213060.1\|2993817_2994282_+\|methylglyoxal-synthase	gnl\|CDD\|179969	PRK05234, mgsA, methylglyoxal synthase; Validated.	2.55286e-93
NZ_CP045145.1\|WP_002213034.1\|2981096_2981621_-\|beta-hydroxyacyl-ACP-dehydratase	gnl\|CDD\|223835	COG0764, FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases [Lipid metabolism].	1.09929e-42
NZ_CP045145.1\|WP_002213058.1\|2992958_2993639_+\|DUF2057-family-protein	gnl\|CDD\|179619	PRK03641, PRK03641, DUF2057 family protein.	4.09411e-122
NZ_CP045145.1\|WP_002213054.1\|2991800_2992118_+\|heat-shock-protein-HspQ	gnl\|CDD\|184526	PRK14129, PRK14129, heat shock protein HspQ; Provisional.	3.64231e-72
NZ_CP045145.1\|WP_002213024.1\|2975573_2976362_-\|SDR-family-oxidoreductase	gnl\|CDD\|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	5.49415e-40
NZ_CP045145.1\|WP_002213032.1\|2979823_2981107_-\|beta-ketoacyl-[acyl-carrier-protein]-synthase-family-protein	gnl\|CDD\|238430	cd00834, KAS_I_II, Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP.	2.93328e-136
NZ_CP045145.1\|WP_002213030.1\|2979084_2979822_-\|SDR-family-oxidoreductase	gnl\|CDD\|187594	cd05333, BKR_SDR_c, beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs. This subgroup includes the Escherichai coli K12 BKR, FabG. BKR catalyzes the NADPH-dependent reduction of ACP in the first reductive step of de novo fatty acid synthesis (FAS). FAS consists of four elongation steps, which are repeated to extend the fatty acid chain through the addition of two-carbo units from malonyl acyl-carrier protein (ACP): condensation, reduction, dehydration, and a final reduction. Type II FAS, typical of plants and many bacteria, maintains these activities on discrete polypeptides, while type I FAS utilizes one or two multifunctional polypeptides. BKR resembles enoyl reductase, which catalyzes the second reduction step in FAS. SDRs are a functionally diverse family of oxidoreductases that have a single domain with structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet) NAD(P)(H) binding region and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRS are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes have a 3-glycine N-terminal NAD(P)(H) binding pattern: TGxxxGxG in classical SDRs. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P) binding motif and an altered active site motif (YXXXN). Fungal type type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P) binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction. A critical catalytic Tyr residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering), is often found in a conserved YXXXK pattern. In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) or additional Ser, contributing to the active site. Substrates for these enzymes include sugars, steroids, alcohols, and aromatic compounds. The standard reaction mechanism is a proton relay involving the conserved Tyr-151 and Lys-155, and well as Asn-111 (or Ser). Some SDR family members, including 17 beta-hydroxysteroid dehydrogenase contain an additional helix-turn-helix motif that is not generally found among SDRs.	2.26541e-68
NZ_CP045145.1\|WP_002213025.1\|2976364_2977117_-\|enoyl-CoA-hydratase	gnl\|CDD\|235936	PRK07110, PRK07110, polyketide biosynthesis enoyl-CoA hydratase; Validated.	2.57932e-133
NZ_CP045145.1\|WP_002221095.1\|2994342_2996397_-\|DNA-helicase-IV	gnl\|CDD\|182930	PRK11054, helD, DNA helicase IV; Provisional.	0
NZ_CP045145.1\|WP_002213038.1\|2982833_2983580_+\|SDR-family-oxidoreductase	gnl\|CDD\|180440	PRK06172, PRK06172, SDR family oxidoreductase.	1.01866e-70

>NZ_CP045145.1|WP_002213036.1|2981884_2982103_-|hypothetical-protein
MYLLQQIELCPDQILHAWKISQNPQVSEVFEIEVVSSEEDAEEAVLFWKAYFSSLGETVIDGRHVGDTFSRF
>NZ_CP045145.1|WP_002213034.1|2981096_2981621_-|beta-hydroxyacyl-ACP-dehydratase
MKNTELNFLKTNFLFNQDITNELNTSFGQDIIKKMIPHREPFLMVDNVELINIECRLIKAIRRVDEKDPVFGGHFPNDPIYPGVLQQESMFQTALILMYFLLNETAIPPAEENIIHAVGTRVYDVFHLSAVRPGELMTIRCCITEYDTFLATAIVQITVNDQIVTVGKGEFHVF
>NZ_CP045145.1|WP_002213032.1|2979823_2981107_-|beta-ketoacyl-[acyl-carrier-protein]-synthase-family-protein
MSSDRIVITGVAINTPIGDTLDLVGNNLLSGKSAIGYWRNFDTSNIYSKIGGQIPEYDIEGKLHAFSNRIPDIVLSRAEKVFKQTTKGVQLSVLMAMEAWLDAGLFEHIIDPFDCGIICGGHNLSDKYLLDQQKIFSDEPEFIDAFSGLNSLDTDHSSSVAQVLNTKGFAYLVGGTCATGNIAIQTAINAIKVDKKQVVAVVCPMASFHPMMLHSLTILEAICYSQYQDTPTKASRPYDINRSGFLPSEGGAVLIFEQAEHAKNRGAKIYAELLGASVNSDANHLGDPSHEGQVRVIQDVLKKCNISPEQVDYVSAHATSTKLGDIVELKSIKRVFGSHAEKLIINAPKSLLGHTMWASGVVEAAIAIWQMRQGEFHQSHNIETLDPAVELNVCASGNVKKEVNIFLNNSFGMGGINSASLFSRYHG
>NZ_CP045145.1|WP_002213030.1|2979084_2979822_-|SDR-family-oxidoreductase
MNLFISGGASGIGRSVVIAALSKGWNVGFSYHNNKEGAQQLLDIAVAEFPRQLCRAYQLDVIDSGAVEYVGDRLLVDFSNIDAVVCNAGIDLPGNLVSMTDEDWALVLNTNLTGTFYLIRYFLPLFLANKYGRIVTLSSLAKDGSSGQAAYAASKAGLVGLTKTTAKEYGHFGITANVVVPGLINTEIIGDDIKGIKNFFAQYAPVGRLGSPSEVAEAILFLVAKESSYVNGAVFNVTGGIDWVY
>NZ_CP045145.1|WP_002213028.1|2977830_2979069_-|hydroxymethylglutaryl-CoA-synthase-family-protein
MNSIGIEKISIYPSSLALKLSELAQARGGDNKYIQESLMVIKRSLVPQWEDAVTLAVNSAKDMLNDQDRSDIGLFIIATESGLDQEKAISTWAHRYLGLPATCRVFELKSACHAGAAALKMAESWISSGLNRGKKVLLINVDISNNMICHGKMEYSLGAGAIALLISDNPVFAVIETGKSGIHTHEVTDVIRPLPWKEVAFDVEASLFSYMDGLENAFEEYCHQTPEARESTYFNYNLYHVPFPGISKEAHKVLLELQGLFGKEALATSFKQKVMPSLYYAQKIGATYCGSIFLSLFSLMVKAPEIKSGDRIGVYSYGSGSCAEYFSMQVGDQAVEIAQQQGAALDILLTQRKILDVAAYEQLENARSAQMQGKDYRLDGDNLQDWYTHHYSGSGLLILERIDNHLRRYRYA
>NZ_CP045145.1|WP_002213026.1|2977118_2977838_-|enoyl-CoA-hydratase/isomerase-family-protein
MHEYVTVPIKFSPDSLADFENRFISALNDERYKVIVLIGGPTYFSMGMDLTYISTHYDADFVSQFCHILKMVRNSHKPVLAKVEGNVIAGGLALLSVVDFILSSDSASFSLPEVTFGITPTIAMSCLLERIRPHHLKYFVWSSSVISAKQALKWGLIDQINTLENLDQDIQVISNKLSRIPKSAIRESKLLLAEQYSFEESLDLGSHLLVERLNDAQTIEKIRHYLEDIKLFNDEYADD
>NZ_CP045145.1|WP_002213025.1|2976364_2977117_-|enoyl-CoA-hydratase
MKKIYLRKSDEGIAFMHINDPVNKNAIDDEFCLQLHGIVDTIKQDKTIKVLILVGLPDIFCTGGTEAFLQSLITHYKTNIEHEYANHLKHFLNIPIPVIAAMEGSATGGGLVLGLYADILVAAEESRYGMSFMNMGFTPGMGSTAMSKEAFGYYTGFEMMVTGNYIRGSELKGKCCFNYILPRAMVMEKAIELATSIAEKPRHSLELLKKYMSIDRRKMLEETSTIEAFMHHIAFNQSNIEQQIQDNYTG
>NZ_CP045145.1|WP_002213024.1|2975573_2976362_-|SDR-family-oxidoreductase
MLNNLSEMTVLVTGGTKGIGRATVESFVKAGAKVYGTYFWGDNLDELENHFSQYLNRPVFLQADISDEEITTQLIEKIAQENKKIDILILNAAFAPQFKDTYKFRGLLDSIEHNSWPLITYIDCIKQHFGQYPGYVVAITSEGHRSCHITGYDYVAASKAVLETLTKYIGARENIIINCISPGVVDTEAFELVFGKKAQAFIRKFDPDFIVSPEAVGNVSVALCSGLMDAVRGQVITVDNGRMFTDNFTKWIDMIETNFIEK
>NZ_CP045145.1|WP_002228570.1|2975046_2975487_-|lipocalin-like-domain-containing-protein
MSNPNRNLFLGRWKLESCIGNSGGIHIYPIGREPFGMLIYTEQYMMVFISSVERTQFSTEDIRAIPSEQIVADFPKFETYCGHYIVNHDEKIVTHFIDNSKIPNQIGTQFRRYFSFEHEKLVLKSIDSLLLNDESWLFELVWNKQE
>NZ_CP045145.1|WP_002213017.1|2974760_2975009_-|acyl-carrier-protein
MDRDHIASIVKKHIVNSIDGAKEHEIDLQKSMADYGASSLDIVSVVSGVMRELKIKIPRTELKNIKSINGLIDLFVTSSSES
>NZ_CP045145.1|WP_002213038.1|2982833_2983580_+|SDR-family-oxidoreductase
MKKTILITGALSGIGNTATKLFSEMGYNVVFSGRRPEEGRVILDDLKRINKDVLYVNADMNSESDIKHLIEMTLERFGSLDVAVNCAGTVGETAEIQAVTQDNFHLVFNTNVLGTLLAMKYQIPVMVERGKGSIINISSIAGLVGLPSTGIYVASKHAIEGLTKTAALEVATTGVRINSISPGPVEGKMFDRFLGHDENNKKAFIEMMPNKRFTTQEEVAHTIVFLAEDNVTAITGQTITIDGGYTAQ
>NZ_CP045145.1|WP_002213039.1|2983733_2986151_+|GNAT-family-N-acetyltransferase
MTTTLDIINSAKDLDPAEYRAFFLQSKAPLFYDLRFLIAAEQSPLLNVSKIFYLLARDEGRLIALVPLYLQEFRSADPLGLLISSAKLSIESEERGLFSHIIHCTDTTIPTLSHDPSLYARIFDAITAIAQAELARYFCFLNVQDGVLLREAQRNGLNINYMVDKFSIELDAFPDFDSFAQALPKYRRYEMVRQLRIFNRSDAKVRILAPPFDNEIEKLARLYYLTTQRLGTPYYWPESQLAVFCRLCGDLVRLIVVEQNGQIVSGFICFEEDGALHFWSAGMDDESSDFSPYTLGVSAVYRYAFEKGINLIECGRLNSHIKTRLGFKPKRLYSIVSQDLGIPAATQTSLSQLKLASQLDGEVRLASHPAFDEWYLTSVWNGRGPTRRPAGIVRAATEADVIRTIVFAKERGMEVSVRGSGHNYVGCFLRVDTLMLDISGLKGLDIDSRHKRAIVESGVSSGQLCHALAAKGLAFPTGHVKEVGISGFLLGGGLGINCSQWGGMSVFNVQALDIVTADGHLRHVSETQEPDLFWAARGAGPCSFFVVTRFYLSCYSLPRVITNSLYTLPFTYLHDLLARLEDASPPTNLQVMVSVSPPTSGDTPAVLLNILAFTDSPQEAQALCESFETRLELPLTALAINQPSNFETIYEQFSSMVVSKRFYADNILTDNTQELVSILSRYLSDAPSRGALTTIFWRGVTTYPQAAFSAHGKFFVSTYAQWDDAKDDSVNKYWLKRMYDELQEIARSRYINEYDLETRAGETSKCFAAENWERLQRLRLEYDPDGVFVDVQQLEEHGDQPGANN
>NZ_CP045145.1|WP_002213046.1|2989796_2990126_+|sulfurtransferase-TusE
MLEFEGRIIDTDAQGYLKNSTDWSEALAPVLAEQEGITLTEPHWEVVRFVRAFYQEFNTSPAIRMLVKAMAQKYGEEKGNSRYLYRLFPKGPAKQATKIAGLPKPVKCI
>NZ_CP045145.1|WP_002213049.1|2990177_2990456_-|acylphosphatase
MSKIYIVAYVYGVVQGVGFRYSTQRQAQQLGVTGYAKNCDDGSVEVVASGNPQAVERLMEWIRQGGPRGARVDRLLTEPYPPTPFETFSIRY
>NZ_CP045145.1|WP_002213052.1|2990549_2991740_+|23S-rRNA-(cytosine(1962)-C(5))-methyltransferase-RlmI
MTVRLILAKGREKSLLRRHPWIFSGAVQRLEGDALSGETIDILDSQGKWLARAAYSPESQILARVWTFQQDEVIDCAFFIRRLQQAQNWRDWLAQRDGLNGYRLIAGESDGLPGITIDRFQNFLVLQLLSAGAEYQRETLVSALQHCYPECSIYDRSDVSVRKKEGLPLTQGLICGEMPPALLPISENGMQLFVDIQQGHKTGFYLDQRDSRLAARNYANGRRVLNCFSYTGAFAVAALMGNCQQVISVDTSQSVLDIAKQNIELNQLDLSKTEFVRDDVFQLLRSYRAQGEKFDLIIMDPPKFVENKSQLASACRGYKDINMLAIQLLRPGGILLSFSCSGLMPVDLFQKILADAALDAGHDIQFIEQFRQAADHPVIAAYPEGLYLKGFACRVM
>NZ_CP045145.1|WP_002213054.1|2991800_2992118_+|heat-shock-protein-HspQ
MIASKFGIGQQVRHSLHGYLGVVIDIDPEYSLAPPEPDEVANNKTLRSSPWYHVVIEDDDGQPVHTYLAEAQLTYEDVDAHPEQPSLDELAASIRHQLQAPHLRN
>NZ_CP045145.1|WP_002213056.1|2992226_2992643_-|CoA-binding-protein
MHDKDIADILKKVKTIALVGASDIPSRPSYRVMAYLLQQGYQVTPVNPKLAGELLLGQLVYAELADIPHAIDMVDVFRNSDAAYCIAQDAIAIGAKVLWLQIGVINEQAAILATDAGLQVVMDRCPKIELPRLGLEKG
>NZ_CP045145.1|WP_002213058.1|2992958_2993639_+|DUF2057-family-protein
MKLGLVAGMLAVCFSFSSVAMTLKLTPEIDLLVVDGKNMSGSLLKGADSLELNSGMHQILFKVIKPLPTDPLVLYSSPPLIVVFNAHNTRSVAIKLPVINTLRDGHQFSKNPLYQLIGDNGHPLSVRHDVLRQDHLNNSTTLETVMAAYNVGKYNASVPAFAAIPPSPVSAVPGTTIPVAGVNTPHKTASLQGENVTEQMLQYWFLQANPETQKRFLIWAKKQPIH
>NZ_CP045145.1|WP_002213060.1|2993817_2994282_+|methylglyoxal-synthase
MELTTRTIAARKHIALVSHDHCKKSLLAWVMENRDLLAQHELYATGTTGNLVQKATGIDVHCLLSGPMGGDQEVGALISEKKIDILIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNRSTADFLIGSTLFSSEVTIAIPDYDRYMQQRLDLK
>NZ_CP045145.1|WP_002221095.1|2994342_2996397_-|DNA-helicase-IV
MELKATSFGKHLSQHPYNRVRLLNAGIEVCGDKHQYLIPFNQLVSIQCKRGIVWGELEFELPQQKVVRLHGTEWQETQHFYHYLLGVWQQWSEEMSQVCAEVLHKQVESIKRIEQQDKWFKRSELGQIQVMIREAFSALPMPVERLAAFESCRADYECCLRWLQQGRHSVERCNQQWTARMLEEYQDFFQNVETSPLNASQSRAVVNGEDSVLVLAGAGSGKTSVLVARAGWLLRRNEALPEQILLLAFGRQAADEMNSRIKQRLGVDSIQAKTFHALALHIIQQGSRKTPVISKLESDSQARRALLIQHWQQQCSEKKAQAKGWREWLTDELEWDVADGDFWQDKRLAARLASRLERWVGLMRMYGGSQAEMIEQANDEVRDLFQKRIRLMAPLLKAWKTALKDEGAVDFSGLIHQAVNLLEKGRFVSPWKHVLVDEFQDISPQRAMLLAALRKQNKQTCLFAVGDDWQAIYRFSGAELSLTTAFSEHFGEGAECALDTTYRFNDRIGDIANRFIQQNPYQLKKPLNSLSKGNKKSVMILPDEQLEALLDKLSGFVKDGERILILARYHHLRPEVLQKAATRWPKLTIDFMTIHASKGQQADYVIIVGLHEGNDGFPAAARESVLEDVLLPPPEDFPDAEERRLLYVAITRAKHQVWLLQDTARPSIFVSQLSELGALVQRKP

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Crispr_ID: NZ_CP045145_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045145_6

3918037-3918116

Orphan

Consensus_repeat	Method
CAGCCGCAGCCACGCTCAGCCATTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045145_6

>merge|NZ_CP045145|6|3918037-3918116|CRISPRCasFinder
CAGCCGCAGCCACGCTCAGCCATTCGACACCCATATCAGAATGACTGCGGCAACGCAGCCGCAGCCACGCTCAGCCATTC

>NZ_CP045145|6|5|3918037-3918116|CRISPRCasFinder
CAGCCGCAGCCACGCTCAGCCATTC	GACACCCATATCAGAATGACTGCGGCAACG
CAGCCGCAGCCACGCTCAGCCATTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045145.1\|WP_002212196.1\|3913407_3914031_+\|SH3-domain-containing-protein	unknown	unknown	gnl\|CDD\|182809
NZ_CP045145.1\|WP_002212199.1\|3916756_3917116_-\|bifunctional-dihydroneopterin-aldolase/7,8-dihydroneopterin-epimerase	unknown	unknown	gnl\|CDD\|183219
NZ_CP045145.1\|WP_002212197.1\|3914190_3915429_+\|multifunctional-CCA-addition/repair-protein	unknown	unknown	gnl\|CDD\|182810
NZ_CP045145.1\|WP_002212201.1\|3918119_3919133_-\|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-transferase-subunit-TsaD	unknown	unknown	gnl\|CDD\|236585
NZ_CP045145.1\|WP_002210360.1\|3924774_3925230_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045145.1\|WP_002212195.1\|3911796_3913104_-\|inorganic-triphosphatase	unknown	unknown	gnl\|CDD\|225569
NZ_CP045145.1\|WP_002212194.1\|3908770_3911626_-\|bifunctional-[glutamate--ammonia-ligase]-adenylyl-L-tyrosine-phosphorylase/[glutamate--ammonia-ligase]-adenylyltransferase	unknown	unknown	gnl\|CDD\|236836
NZ_CP045145.1\|WP_002210361.1\|3925256_3925727_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045145.1\|WP_002210359.1\|3921795_3923634_+\|RNA-polymerase-sigma-factor-RpoD	unknown	unknown	gnl\|CDD\|235549
NZ_CP045145.1\|WP_002217581.1\|3917223_3917874_+\|glycerol-3-phosphate-1-O-acyltransferase-PlsY	unknown	unknown	gnl\|CDD\|234691
NZ_CP045145.1\|WP_002210362.1\|3925735_3927118_-\|HNH-endonuclease	unknown	unknown	gnl\|CDD\|238038
NZ_CP045145.1\|WP_002212193.1\|3907205_3908636_-\|bifunctional-D-glycero-beta-D-manno-heptose-7-phosphate-kinase/D-glycero-beta-D-manno-heptose-1-phosphate-adenylyltransferase-HldE	unknown	unknown	gnl\|CDD\|183085
NZ_CP045145.1\|WP_002214241.1\|3927250_3927481_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045145.1\|WP_000255944.1\|3929628_3930651_-\|IS21-like-element-IS100-family-transposase	unknown	unknown	gnl\|CDD\|226950
NZ_CP045145.1\|WP_002212192.1\|3905918_3907169_-\|L-methionine/branched-chain-amino-acid-transporter	unknown	unknown	gnl\|CDD\|236823
NZ_CP045145.1\|WP_001144069.1\|3919538_3919754_+\|30S-ribosomal-protein-S21	unknown	unknown	gnl\|CDD\|234707
NZ_CP045145.1\|WP_002212191.1\|3905312_3905594_+\|accessory-factor-UbiK-family-protein	unknown	unknown	gnl\|CDD\|225508
NZ_CP045145.1\|WP_002212198.1\|3915664_3916483_-\|undecaprenyl-diphosphate-phosphatase	unknown	unknown	gnl\|CDD\|234712
NZ_CP045145.1\|WP_001297096.1\|3928849_3929629_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|181681
NZ_CP045145.1\|WP_002210358.1\|3919889_3921638_+\|DNA-primase	unknown	unknown	gnl\|CDD\|235551

Protein	Function_ID	Function_description	E-value
NZ_CP045145.1\|WP_002212196.1\|3913407_3914031_+\|SH3-domain-containing-protein	gnl\|CDD\|182809	PRK10884, PRK10884, SH3 domain-containing protein; Provisional.	4.34503e-147
NZ_CP045145.1\|WP_002212199.1\|3916756_3917116_-\|bifunctional-dihydroneopterin-aldolase/7,8-dihydroneopterin-epimerase	gnl\|CDD\|183219	PRK11593, folB, bifunctional dihydroneopterin aldolase/7,8-dihydroneopterin epimerase.	2.02028e-82
NZ_CP045145.1\|WP_002212197.1\|3914190_3915429_+\|multifunctional-CCA-addition/repair-protein	gnl\|CDD\|182810	PRK10885, cca, multifunctional CCA addition/repair protein.	0
NZ_CP045145.1\|WP_002212201.1\|3918119_3919133_-\|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-transferase-subunit-TsaD	gnl\|CDD\|236585	PRK09604, PRK09604, tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD.	0
NZ_CP045145.1\|WP_002212195.1\|3911796_3913104_-\|inorganic-triphosphatase	gnl\|CDD\|225569	COG3025, COG3025, Uncharacterized conserved protein [Function unknown].	0
NZ_CP045145.1\|WP_002212194.1\|3908770_3911626_-\|bifunctional-[glutamate--ammonia-ligase]-adenylyl-L-tyrosine-phosphorylase/[glutamate--ammonia-ligase]-adenylyltransferase	gnl\|CDD\|236836	PRK11072, PRK11072, bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase.	0
NZ_CP045145.1\|WP_002210362.1\|3925735_3927118_-\|HNH-endonuclease	gnl\|CDD\|238038	cd00085, HNHc, HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and anaredoxins.	2.83623e-06
NZ_CP045145.1\|WP_002210359.1\|3921795_3923634_+\|RNA-polymerase-sigma-factor-RpoD	gnl\|CDD\|235549	PRK05658, PRK05658, RNA polymerase sigma factor RpoD; Validated.	0
NZ_CP045145.1\|WP_002217581.1\|3917223_3917874_+\|glycerol-3-phosphate-1-O-acyltransferase-PlsY	gnl\|CDD\|234691	PRK00220, PRK00220, glycerol-3-phosphate 1-O-acyltransferase PlsY.	6.06402e-111
NZ_CP045145.1\|WP_002212193.1\|3907205_3908636_-\|bifunctional-D-glycero-beta-D-manno-heptose-7-phosphate-kinase/D-glycero-beta-D-manno-heptose-1-phosphate-adenylyltransferase-HldE	gnl\|CDD\|183085	PRK11316, PRK11316, bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE.	0
NZ_CP045145.1\|WP_000255944.1\|3929628_3930651_-\|IS21-like-element-IS100-family-transposase	gnl\|CDD\|226950	COG4584, COG4584, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	3.49492e-79
NZ_CP045145.1\|WP_002212192.1\|3905918_3907169_-\|L-methionine/branched-chain-amino-acid-transporter	gnl\|CDD\|236823	PRK11021, PRK11021, putative transporter; Provisional.	0
NZ_CP045145.1\|WP_001144069.1\|3919538_3919754_+\|30S-ribosomal-protein-S21	gnl\|CDD\|234707	PRK00270, rpsU, 30S ribosomal protein S21; Reviewed.	8.25342e-17
NZ_CP045145.1\|WP_002212191.1\|3905312_3905594_+\|accessory-factor-UbiK-family-protein	gnl\|CDD\|225508	COG2960, COG2960, Uncharacterized protein conserved in bacteria [Function unknown].	1.21559e-35
NZ_CP045145.1\|WP_002212198.1\|3915664_3916483_-\|undecaprenyl-diphosphate-phosphatase	gnl\|CDD\|234712	PRK00281, PRK00281, undecaprenyl-diphosphate phosphatase.	5.08833e-116
NZ_CP045145.1\|WP_001297096.1\|3928849_3929629_-\|AAA-family-ATPase	gnl\|CDD\|181681	PRK09183, PRK09183, transposase/IS protein; Provisional.	5.26232e-178
NZ_CP045145.1\|WP_002210358.1\|3919889_3921638_+\|DNA-primase	gnl\|CDD\|235551	PRK05667, dnaG, DNA primase; Validated.	0

>NZ_CP045145.1|WP_002217581.1|3917223_3917874_+|glycerol-3-phosphate-1-O-acyltransferase-PlsY
MSAIALGMIIFAYLCGSISSAILVCRVARLPDPRTHGSGNPGATNVLRIGGRTAAVAVLLFDILKGMLPVWIAYLLHIPPLYLGLTAIAACLGHIYPVFFHFKGGKGVATAFGAIAPIGWDLTGLMTGTWLLTVLLSGYSSLGAIVSALIAPFYVWWFKPQFTFPVAMLSCLILMRHHDNIQRLWRGKEGKIWDKLRKKKQKTPAEEAAELEEKED
>NZ_CP045145.1|WP_002212199.1|3916756_3917116_-|bifunctional-dihydroneopterin-aldolase/7,8-dihydroneopterin-epimerase
MDIVFIEELSVITTIGVYDWEQTIQQKLVFDIEMGWDNRKAAGSDDVNDCLSYADISEAVIQHVGSQRFALVERVAEEVAELLLRRFNSPWVRIKVSKPGAVAQAKNVGVIIERGQRLS
>NZ_CP045145.1|WP_002212198.1|3915664_3916483_-|undecaprenyl-diphosphate-phosphatase
MTDMYSLFVAFILGVVEGLTEFLPVSSTGHMIIVGELLGFTGDKAKTFEVIIQLGSILAVVVVFWRRLFGLIGIHFGAVPHEGKTNGHLTLGHILLAMIPAVILGLAFHDVIKALFDPKSVMYALVAGGVLLLAAEWLKPKNPKAVGLDDITYRQAFAIGCFQCLALWPGFSRSGATISGGMLVGVNRYAASEFSFILAVPMMIGASGLDLYKSLHFLTLGDLPMFAVGFITAFIVALIAIKTFLSLIKRISFVPFAIYRFIVAAVVYWVFM
>NZ_CP045145.1|WP_002212197.1|3914190_3915429_+|multifunctional-CCA-addition/repair-protein
MNIYLVGGAVRDSLLNLPVTEQDWVVVGATPEQLLKLGYQQVGKDFPVFLHPVSHEEYALARTERKSGQGYTGFTCYAAPDVTLEDDLLRRDLTVNAIARSADGEFIDPYHGKQDLENRVLRHVSDAFGEDPLRVLRVARFAARFAYLGFTIAPETMSLMSNMAQSGELSALTPERVWKETEKALKTQSPHVYFQVLRDCGALAVLFPEIERLFGVPAPEKWHPEIDTGIHTLMTLAIAAQLSPEVDIRFAALCHDLGKGLTPKEHWPHHHGHGPAGVKLVEQLCQRLRIPNPVRDLAKLVAEYHDLIHTVNKLRPETLLKLFNAIDVWRKPERLEQMIMTSEADARGRTGFENNPYPQGDYLRAAFQIANGVSIQEVVASGLQGLAIRDELQRRRQQALAEWKQTQETASI
>NZ_CP045145.1|WP_002212196.1|3913407_3914031_+|SH3-domain-containing-protein
MQKLRLICLTILSVSLSWGAQAEEKRYISDELDTYVHSGPGNQYRIVGTLKGGDEVTLISVDNGTNYGQIRDSKGKTTWIPLNQLSETPSLRVRVPDLEQQVKTLTDKLANIDNSWNQRTAEMQQKVAASDSVISELQKENESLKNQLIVAQKKVNAVNLQLDDKQRTIILQWFMYGGGVAGIGLLLGLVLPHLIPSRKKNNRWMNC
>NZ_CP045145.1|WP_002212195.1|3911796_3913104_-|inorganic-triphosphatase
MTVEIELKFIATPAAIAALPEWIESQKNQHFPPQTLANIYFDTADKRLRQNDIGLRIRGYDGRYEMTVKTGGKVVGGLHQRPEYNVDIDSDQLDLARFPQDIWPEGWAVDLLQAELQPLFRTDFTREKWVITYGESEIELALDQGSISADTLSEPLSEIELELKQGTQGDLLALAAELAKMGGLRQSNLSKAARGYHLAQGNPPRELRPFLVFQPVAKSTVEQGMAGGLESILEHWQYHEELWLRGEPAAKTMIIDALAMVRQSLAIFGGLVPRKASTELRALLIALEPQLEPKSVDAALLCYSVDYLKCKLALTSWLITAGWRPFMDAKAQAKFDGSFKRFCDIMLSRSAADLKEAFGHNLDDDGYLAQLPRLNRQLIAFQLLSGFYPQSEWHPYIDAWFGLQQAIMARQGHWRDTARKEALSQAAFWLNGAVR
>NZ_CP045145.1|WP_002212194.1|3908770_3911626_-|bifunctional-[glutamate--ammonia-ligase]-adenylyl-L-tyrosine-phosphorylase/[glutamate--ammonia-ligase]-adenylyltransferase
MLPLPSELQIQAQSIKQRFSELPAPPDLRDEDIAVLALSDFVSDMLLIHPQWLEELHQQPPQPQEWQYYSQWLSQALAGVQDEAALLTALRLFRRRVMVRIAWSQVLQTSGTAETLQQLSTLAESMIIAARDWLYQVCCRELGTPCNRQGVPQPLLILGMGKLGGGELNFSSDIDLIFAYPENGQTQGGRRELDNAQFFTRLGQRLIKALDQHTIDGFVYRVDMRLRPFGDSGPLVLSFAALEDYYQEQGRDWERYAMVKARLMGGADDPYSQELRQMLRPFVFRRYIDFSVIQSLRNMKGMIAREVRRRGLKDNIKLGAGGIREIEFITQVFQLIRGGREPRLQERALLPTLQAVAELGLLPEQQVADLSGSYLFLRRLENLLQAIADEQTQTLPNDPLNQARLAWGMGYADWAAMSTALENHMQAVRVVFDDLIGDETPDIGEDPSHGLYKSLWQDVLEESDLAPLTPHLEEAARRQLLATISGFRHDVDKRTIGPRGREVLDQLMPRLFAEVCPRPDANVALSRLILLLLSIVTRTTYLELLVEYHAALKHVIRLCSASPMVASQLARYPLLLDELLDPQSLYQPLAPSAYRDELRQYLLRVPEDDEEQQLEALRQFKQAQQLRIAAGDITEALPVMKVSDHLTYLAEAIIDAVIQQAWNQMVARYGQPSHLQQSEGRGFAVIGYGKLGGWELGYSSDLDLVFLLDCPLDVMTDGDRSIDGRQFYLRLAQRIMHLFSTRTSSGILYEVDARLRPSGEAGMLVSTIEAFADYQRNEAWTWEHQALVRARIVYGSPKLHQQFDAIRQQILCRHREDPQLQQEVREMREKMRNHLGSKQRDIFDIKADAGGITDIEFIAQYLVLRYAASEPRLTRWSDNVRIFESMAHYDIMSPEEAAALTRAYVTMRDEIHHLALQEQSSKVAADSFIAEREQVAASWHKWLAANDANVS
>NZ_CP045145.1|WP_002212193.1|3907205_3908636_-|bifunctional-D-glycero-beta-D-manno-heptose-7-phosphate-kinase/D-glycero-beta-D-manno-heptose-1-phosphate-adenylyltransferase-HldE
MKVTLPDFRRAGVLVVGDVMLDRYWYGPTCRISPEAPVPVVKVDTIEERPGGAANVAMNIASLGAVARLVGLTGIDDAARALICKLSEVRVRCDFVSVPTHPTITKLRVLSRNQQLIRLDFEEGFDGVDPTPIFERIQLALPQIGALVLSDYAKGALNSVQPMIQLARKANVPVLIDPKGSDFERYRGATLLTPNLSEFEAVVGRCKNEEELVNRGMQLVADFELSALLVTRSEQGMTLLQLGKPPLHLPTQAKEVFDVTGAGDTVIGVLAAALAAGNSLEESCFLANAAAGVVVGKLGTSTVSPIELENAIRGRAETGFGVMDEQQLKIAVAQARQRGEKVVMTNGIFDILHAGHVSYLANARKLGDRLIVAVNSDASTKRLKGEKRPVNPLEQRMVVLGALEAVDWVVPFEEDTPQRLIADILPDLLVKGGDYKPHEIAGSEEVWAAGGEVKVLNFEDGVSTTNIIQSIKNGRG
>NZ_CP045145.1|WP_002212192.1|3905918_3907169_-|L-methionine/branched-chain-amino-acid-transporter
MGGLKQELSLAQGVGLLSTSLLGTGVFAVPALAAMLAGHDSLWAWPVLIVLVFPIAIAFAALGRHFPSAGGAAHFVAIAFGPKLGKVTGWLFLSVIPVGLPAALQIAAGFWQAMFGWSDTGLLMVQLVTLLVIWLLGTRSAGSSANLQTVIALLVIALVAAIWWQGDIRLSQIPWPALQDVSPPNIFNALAVMFWCFVGLEAFAHLATEFRHPERDFPRALIVGLLVAGAVYWGCTVAVLHFQAYGESQAAAASLPGIVVQLFGEHALWIACIIGYLACFASVNIYTQSFARMVWSQSQVRPQSKLARLSAGQTPVNALTAVVGSCLVFALLIYWLALPLDLLIVYANGIFVLIYLLCMLAGIRLLSGRARVMSVIGSLLCCVLLVMIGWKSVYALLMFALLWMLMSKPKTQLTQP
>NZ_CP045145.1|WP_002212191.1|3905312_3905594_+|accessory-factor-UbiK-family-protein
MIDPKKIEQIARQVHESMPKGIREFGEDVEKKIRLILQSQLTRLDLVNREEFDVQTQVLLRTREKLALLEQRVGALEAKFNSAPADHGEKTGE
>NZ_CP045145.1|WP_002212201.1|3918119_3919133_-|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-transferase-subunit-TsaD
MRVLGIETSCDETGIAVYDDKAGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQAALKEANLSAKDIDAVAYTAGPGLVGALLVGATIGRALAFAWGVPAVPVHHMEGHLLAPMLEENAPEFPFVALLVSGGHTQLISVTGIGEYLLLGESVDDAAGEAFDKTAKLLGLDYPGGPMLSRMAQQGTVGRFTFPRPMTDRPGLDFSFSGLKTFAANTIRANGDDDQTRADIARAFEDAVVDTLAIKSKRALDQTGFKRLVIAGGVSANQTLRLKLADMMQKRGGEVFYARPEFCTDNGAMIAYAGMVRLRSNLNSELSVSVRPRWPLSELPKV
>NZ_CP045145.1|WP_001144069.1|3919538_3919754_+|30S-ribosomal-protein-S21
MPVIKVRENEPFDVALRRFKRSCEKAGVLAEVRRREFYEKPTTERKRAKASAVKRHAKKLARENARRTRLY
>NZ_CP045145.1|WP_002210358.1|3919889_3921638_+|DNA-primase
MAGRIPRVFINDLLARTDIIDLIDARVKLKKQGKNYHACCPFHHEKTPSFTVNGEKQFYHCFGCGAHGNAVDFLMNYDRLEFVESIEELATMHGLEVPYEAGSGTTQIERHQRQSLYQLMESLSAFYQQSLKGQNAKQAREYLKHRGLSEEIIQHFAIGFAPPGWDNALKRFGRDGESRTALNDAGMLVTNDTGRTYDRFRERVMFPIRDKRGRVIAFGGRILGDGVPKYLNSPETEIFHKGRQLYGLYEAQVNHPNPTRLLVVEGYMDVVALAQFGIDYAVASLGTATTAEHIQLLFRATDNVICCYDGDRAGRDAAWRALETALPYLNDGRQLRFMFLPDGEDPDTLVRKEGKDAFEQRMEAAQPLSTFLFETLMPQVDLSSPDGRAKLSTLALPLISQVPGEALRLYLRQQLGNKLGLLDDSQLDKLMPKQIDNANTYQPPQLKRTTMRILIGLLVQNPQLATLIPSLQGLEQAKLAGLPLFIELVETCLAQPGLTTGQLLELYRDNKFSQQLETLATWNHMIVEDMVEPTFVDTLASLYDSILEQRQETLIARDRTHGLNAEERKELWSLNLALARKK
>NZ_CP045145.1|WP_002210359.1|3921795_3923634_+|RNA-polymerase-sigma-factor-RpoD
MEQNPQSQLKLLVTRGKEQGYLTYAEVNDHLPEDIVDSDQIEDIIQMINDMGIQVLEEAPDADDLMLAENTTDTDDDAAEAAAQVLSSVESEIGRTTDPVRMYMREMGTVELLTREGEIDIAKRIEDGINQVQCSVAEYPEAITYLLEQYDRVEAGESRLSDLITGFVDPNAEEDIAPTATHVGSELSTEEMDDEDEDEDEDDDAEDDNSIDPELARQKFSDLREQYENARMEIKKNGRNHANAAAEILKLSEVFKQFRLVPKQFDYLVNNMRAMMDRVRTQERIIMKLCVEQCKMPKKNFVTLFSSNETSDTWFNAAVAMGKPWSEKLKDVSEDVQRSLQKLRQIEEETGLTIEQVKDINRRMSIGEAKARRAKKEMVEANLRLVISIAKKYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQARTIRIPVHMIETINKLNRISRQMLQEMGREPTPEELAERMLMPEDKIRKVLKIAKEPISMETPIGDDEDSHLGDFIEDTTLELPLDSATSESLRSATHDVLAGLTAREAKVLRMRFGIDMNTDHTLEEVGKQFDVTRERIRQIEAKALRKLRHPSRSEVLRSFLDD
>NZ_CP045145.1|WP_002210360.1|3924774_3925230_-|hypothetical-protein
MANLEKAVNEFTRISKSMGYNINPPYTGKLETYDFGRDISPEQPDFWKQYGSFLRISNGSFADGCVFYGMSGGEDDAGLIEFNNALNIPDFKDETMTGLIVIGGNNTDTFYYDPRTGKWEACDRIGTDRVWESCDSLAELIETQIKMLENG
>NZ_CP045145.1|WP_002210361.1|3925256_3925727_-|hypothetical-protein
MTDIEKAVTTFQAYRAAIGYPKIPPYEGEVIEYDFGRKIESNQPDFWTQYHEFLRLSDGLAADGVYFYGIACEGKLIGNRLIDNNDALRDGEMYDESMDGLIAIGSSNSDIFVYDTNTHKWESRDRIAIDDINESYDTLAELIDSQLQRINIGDAF
>NZ_CP045145.1|WP_002210362.1|3925735_3927118_-|HNH-endonuclease
MSFNLPGMYLYYLSRDNLAPEEYERIISPHAAWARICREYEFDDSHNTSRYLINMREREQRSSPDQPRPGGIREKEKLEKLVFSGDVVMLSDMYGPARLFYINGEGQLMSTDPHAFRFEGAAKIIKAFDDSVKCRNYQRTGGKPRSTQTRRLKSTTNTIPDRSMVTRASDESGRVLSAKWQSVTDSAKTLWEATPFTHDKATTEAARGRIADGAVGTLEGLGTLMGPSAQEYMAGAFNPEQAAINKVRQQNQQAAGKAIYDNTKGAVTDAYQRNGLAGAAAMVVTASVAELAGTKGLGTVEKVGTLGDVAKLGKAVELEKLEGYLGTYKGQKVLLQNVDVVKMDYVRRSTADRNLLRKEFDNGVRKKFLKDIANNPEVVKRLDAFDRSVLAKGVVPDGYQVHHKLPLDDSGNNNFDNLVLISTRPEHAAFTTTQKHITKNLTPTGTNIVLWPKPQGIIYP
>NZ_CP045145.1|WP_002214241.1|3927250_3927481_-|hypothetical-protein
MDTLTTATPSVHRKYFRHILGACGSCYFERQAGKFILGEEGDQFFSAYVREDSAYRIERMESESPLGYQTSGAIPV
>NZ_CP045145.1|WP_001297096.1|3928849_3929629_-|AAA-family-ATPase
MMELQHQRLMALAGQLQLESLISAAPALSQQAVDQEWSYMDFLEHLLHEEKLARHQRKQAMYTRMAAFPAVKTFEEYDFTFATGAPQKQLQSLRSLSFIERNENIVLLGPSGVGKTHLAIAMGYEAVRAGIKVRFTTAADLLLQLSTAQRQGRYKTTLQRGVMAPRLLIIDEIGYLPFSQEEAKLFFQVIAKRYEKSAMILTSNLPFGQWDQTFAGDAALTSAMLDRILHHSHVVQIKGESYRLRQKRKAGVIAEANPE
>NZ_CP045145.1|WP_000255944.1|3929628_3930651_-|IS21-like-element-IS100-family-transposase
MVTFETVMEIKILHKQGMSSRAIARELGISRNTVKRYLQAKSEPPKYTPRPAVASLLDEYRDYIRQRIADAHPYKIPATVIAREIRDQGYRGGMTILRAFIRSLSVPQEQEPAVRFETEPGRQMQVDWGTMRNGRSPLHVFVAVLGYSRMLYIEFTDNMRYDTLETCHRNAFRFFGGVPREVLYDNMKTVVLQRDAYQTGQHRFHPSLWQFGKEMGFSPRLCRPFRAQTKGKVERMVQYTRNSFYIPLMTRLRPMGITVDVETANRHGLRWLHDVANQRKHETIQARPCDRWLEEQQSMLALPPEKKEYDVHLDENLVNFDKHPLHHPLSIYDSFCRGVA

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Crispr_ID: NZ_CP045145_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045145_7

4463974-4464085

Orphan

Consensus_repeat	Method
AAAGCACATTTGAGCAGCGAGTGAAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045145_7

>merge|NZ_CP045145|7|4463974-4464085|CRISPRCasFinder
AAAGCACATTTGAGCAGCGAGTGAAGCCAGACCATCATCCTTAGGCTTTTAATACGTTTTTGATTTTGAATGGGTTGTTGACGTCCAAAGCACATTTGAGCAGCCGAGTGAA

>NZ_CP045145|7|6|4463974-4464085|CRISPRCasFinder
AAAGCACATTTGAGCAGCGAGTGAAG	CCAGACCATCATCCTTAGGCTTTTAATACGTTTTTGATTTTGAATGGGTTGTTGACGTCC
AAAGCACATTTGAGCAGCCGAGTGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045145.1\|WP_002209485.1\|4452552_4455045_-\|TonB-dependent-hemoglobin/transferrin/lactoferrin-family-receptor	unknown	unknown	gnl\|CDD\|273807
NZ_CP045145.1\|WP_002209487.1\|4455643_4457017_-\|argininosuccinate-lyase	unknown	unknown	gnl\|CDD\|179883
NZ_CP045145.1\|WP_002209489.1\|4458125_4459130_-\|N-acetyl-gamma-glutamyl-phosphate-reductase	unknown	unknown	gnl\|CDD\|234761
NZ_CP045145.1\|WP_002209483.1\|4449739_4451548_-\|type-I-secretion-system-permease/ATPase	unknown	unknown	gnl\|CDD\|226969
NZ_CP045145.1\|WP_002208938.1\|4473067_4475266_+\|primosomal-protein-N'	unknown	unknown	gnl\|CDD\|235514
NZ_CP045145.1\|WP_002208934.1\|4466952_4469388_-\|bifunctional-aspartate-kinase/homoserine-dehydrogenase-II	unknown	unknown	gnl\|CDD\|236530
NZ_CP045145.1\|WP_002208942.1\|4477657_4478182_+\|ATP-dependent-protease-subunit-HslV	unknown	unknown	gnl\|CDD\|235477
NZ_CP045145.1\|WP_002208941.1\|4476712_4477558_+\|cell-division-protein-FtsN	unknown	unknown	gnl\|CDD\|237191
NZ_CP045145.1\|WP_002209491.1\|4460917_4463554_+\|phosphoenolpyruvate-carboxylase	unknown	unknown	gnl\|CDD\|234570
NZ_CP045145.1\|WP_002209488.1\|4457183_4457957_-\|acetylglutamate-kinase	unknown	unknown	gnl\|CDD\|239782
NZ_CP045145.1\|WP_002216737.1\|4472609_4472825_-\|50S-ribosomal-protein-L31	unknown	unknown	gnl\|CDD\|234576
NZ_CP045145.1\|WP_002209484.1\|4451713_4452331_-\|hemophore-HasA	unknown	unknown	gnl\|CDD\|368907
NZ_CP045145.1\|WP_002216730.1\|4475618_4476647_+\|DNA-binding-transcriptional-regulator-CytR	unknown	unknown	gnl\|CDD\|182923
NZ_CP045145.1\|WP_002208936.1\|4471593_4472049_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227027
NZ_CP045145.1\|WP_002208935.1\|4470927_4471245_+\|met-regulon-transcriptional-regulator-MetJ	unknown	unknown	gnl\|CDD\|179982
NZ_CP045145.1\|WP_002223919.1\|4459380_4460544_+\|acetylornithine-deacetylase	unknown	unknown	gnl\|CDD\|235346
NZ_CP045145.1\|WP_100067904.1\|4464295_4465650_+\|IS3-like-element-IS1661-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP045145.1\|WP_002209481.1\|4447467_4448271_-\|energy-transducer-TonB	unknown	unknown	gnl\|CDD\|223880
NZ_CP045145.1\|WP_002208933.1\|4465835_4466720_-\|methylenetetrahydrofolate-reductase	unknown	unknown	gnl\|CDD\|181852
NZ_CP045145.1\|WP_002209482.1\|4448335_4449664_-\|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|130902

Protein	Function_ID	Function_description	E-value
NZ_CP045145.1\|WP_002209485.1\|4452552_4455045_-\|TonB-dependent-hemoglobin/transferrin/lactoferrin-family-receptor	gnl\|CDD\|273807	TIGR01785, Heme/hemopexin_utilization_protein_C, TonB-dependent heme/hemoglobin receptor family protein. This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins].	8.20794e-132
NZ_CP045145.1\|WP_002209487.1\|4455643_4457017_-\|argininosuccinate-lyase	gnl\|CDD\|179883	PRK04833, PRK04833, argininosuccinate lyase; Provisional.	0
NZ_CP045145.1\|WP_002209489.1\|4458125_4459130_-\|N-acetyl-gamma-glutamyl-phosphate-reductase	gnl\|CDD\|234761	PRK00436, argC, N-acetyl-gamma-glutamyl-phosphate reductase; Validated.	0
NZ_CP045145.1\|WP_002209483.1\|4449739_4451548_-\|type-I-secretion-system-permease/ATPase	gnl\|CDD\|226969	COG4618, ArpD, ABC-type protease/lipase transport system, ATPase and permease components [General function prediction only].	0
NZ_CP045145.1\|WP_002208938.1\|4473067_4475266_+\|primosomal-protein-N'	gnl\|CDD\|235514	PRK05580, PRK05580, primosome assembly protein PriA; Validated.	0
NZ_CP045145.1\|WP_002208934.1\|4466952_4469388_-\|bifunctional-aspartate-kinase/homoserine-dehydrogenase-II	gnl\|CDD\|236530	PRK09466, metL, bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional.	0
NZ_CP045145.1\|WP_002208942.1\|4477657_4478182_+\|ATP-dependent-protease-subunit-HslV	gnl\|CDD\|235477	PRK05456, PRK05456, ATP-dependent protease subunit HslV.	1.88144e-131
NZ_CP045145.1\|WP_002208941.1\|4476712_4477558_+\|cell-division-protein-FtsN	gnl\|CDD\|237191	PRK12757, PRK12757, cell division protein FtsN; Provisional.	2.3223e-148
NZ_CP045145.1\|WP_002209491.1\|4460917_4463554_+\|phosphoenolpyruvate-carboxylase	gnl\|CDD\|234570	PRK00009, PRK00009, phosphoenolpyruvate carboxylase; Reviewed.	0
NZ_CP045145.1\|WP_002209488.1\|4457183_4457957_-\|acetylglutamate-kinase	gnl\|CDD\|239782	cd04249, AAK_NAGK-NC, AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of ornithine biosynthesis. There are two variants of this pathway. In one, typified by the pathway in Escherichia coli, glutamate is acetylated by acetyl-CoA and acetylornithine is deacylated hydrolytically. In this pathway, feedback inhibition by arginine occurs at the initial acetylation of glutamate and not at the phosphorylation of NAG by NAGK. Homodimeric NAGK-NC are members of the Amino Acid Kinase Superfamily (AAK).	2.92616e-136
NZ_CP045145.1\|WP_002216737.1\|4472609_4472825_-\|50S-ribosomal-protein-L31	gnl\|CDD\|234576	PRK00019, rpmE, 50S ribosomal protein L31; Reviewed.	4.16591e-39
NZ_CP045145.1\|WP_002209484.1\|4451713_4452331_-\|hemophore-HasA	gnl\|CDD\|368907	pfam06438, HasA, Heme-binding protein A (HasA). Free iron is limited in vertebrate hosts, thus an alternative to siderophores has been developed by pathogenic bacteria to access host iron bound in protein complexes. HasA is a secreted hemophore that has the ability to obtain iron from hemoglobin. Once bound to HasA, the heme is shuttled to the receptor HasR, which releases the heme into the bacterium.	9.51098e-102
NZ_CP045145.1\|WP_002216730.1\|4475618_4476647_+\|DNA-binding-transcriptional-regulator-CytR	gnl\|CDD\|182923	PRK11041, PRK11041, DNA-binding transcriptional regulator CytR; Provisional.	0
NZ_CP045145.1\|WP_002208936.1\|4471593_4472049_+\|hypothetical-protein	gnl\|CDD\|227027	COG4682, COG4682, Predicted membrane protein [Function unknown].	3.96467e-66
NZ_CP045145.1\|WP_002208935.1\|4470927_4471245_+\|met-regulon-transcriptional-regulator-MetJ	gnl\|CDD\|179982	PRK05264, PRK05264, met regulon transcriptional regulator MetJ.	5.3482e-81
NZ_CP045145.1\|WP_002223919.1\|4459380_4460544_+\|acetylornithine-deacetylase	gnl\|CDD\|235346	PRK05111, PRK05111, acetylornithine deacetylase; Provisional.	0
NZ_CP045145.1\|WP_100067904.1\|4464295_4465650_+\|IS3-like-element-IS1661-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	9.01643e-48
NZ_CP045145.1\|WP_002209481.1\|4447467_4448271_-\|energy-transducer-TonB	gnl\|CDD\|223880	COG0810, TonB, Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane].	1.51188e-39
NZ_CP045145.1\|WP_002208933.1\|4465835_4466720_-\|methylenetetrahydrofolate-reductase	gnl\|CDD\|181852	PRK09432, metF, methylenetetrahydrofolate reductase.	0
NZ_CP045145.1\|WP_002209482.1\|4448335_4449664_-\|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit	gnl\|CDD\|130902	TIGR01843, Hemolysin_secretion_protein_D_plasmid, type I secretion membrane fusion protein, HlyD family. Type I secretion is an ABC transport process that exports proteins, without cleavage of any signal sequence, from the cytosol to extracellular medium across both inner and outer membranes. The secretion signal is found in the C-terminus of the transported protein. This model represents the adaptor protein between the ATP-binding cassette (ABC) protein of the inner membrane and the outer membrane protein, and is called the membrane fusion protein. This model selects a subfamily closely related to HlyD; it is defined narrowly and excludes, for example, colicin V secretion protein CvaA and multidrug efflux proteins. [Protein fate, Protein and peptide secretion and trafficking].	3.16318e-105

>NZ_CP045145.1|WP_002209491.1|4460917_4463554_+|phosphoenolpyruvate-carboxylase
MNEQYSAMRSNVSMLGTLLGDTIKEALGEHILDRVETIRKLSKSSRAGNEASRQELLTTLQNLSNDELLPVARAFSQFLNLTNTAEQYHSISPHGEAASNPEALAQLFTRLKDKKLSDQDMRSAVDDLSIELVLTAHPTEITRRTLIHKLVEVNTCLSQLDHNDLADYERNKIMRRLRQLVAQSWHTDEIRKLRPSPVDEAKWGFAVVENSLWEGVPAFLREFNEQLENSLDYRLPVEAVPIRFTSWMGGDRDGNPNVTAEITRHVLLLSRWKATDLFLRDIQVLVSELSMSECTPELRELAGGEEVLEPYRQLMKNVRTQLTNTQAYLEARLKGERVLPPHDLLVSNDQLWEPLYACYQSLKACGMEIIANGQLLDTLRRVRCFGVPLVRIDVRQESTRHTDAIAELTRYLGLGDYESWSESDKQAFLVRELNSKRPLVPLKWEPSAETQEVLETCRVIAEAPQGSIAAYVISMAKVPSDVLAVHLLLKEAGCPFTLPVAPLFETLDDLNNADDVMTQLLGIDWYRGLIQGKQMVMIGYSDSAKDAGVMAASWAQYRAQDALIKTCEKAGITLTLFHGRGGSIGRGGAPAHAALLSQPPGSLKGGLRVTEQGEMIRFKFGLPEVTISSLALYAGAILEANLLPPPEPKKEWIEVMDLLSDASCDMYRSYVRENPEFVRYFRAATPELELGKLPLGSRPAKRRPDGGVESLRAIPWIFAWTQNRLMLPAWLGAGAGLQRAIDAGKQDVLATMCRDWPFFSTRIGMLEMVFAKADLWLAEYYDQRLVDKSLWPLGQQLRDQLAADIKVVLAIANDDHLMADLPWIAESIALRNVYTDPLNVLQAELLHRSRQQEHPDACVEQALMVTIAGVAAGMRNTG
>NZ_CP045145.1|WP_002223919.1|4459380_4460544_+|acetylornithine-deacetylase
MKLPPFIELYRALIATPSISAADSALDQSNEALINLLAGWFADLGFRVEIQPVPDTRHKFNLLASIGENENGEGHGGLLLAGHTDTVPYDEGRWTRDPFTLTEHDHKLYGLGTADMKGFFAFILDAVRDIDASKLTKPLYILATADEETTMAGARYFAANTQLRPDFAIIGEPTSLQPVRAHKGHISNAIRITGQSGHSSDPARGVNAIDLMHESITQLMALRTTLQERYHNPAFTIPYPTMNFGHINGGDAANRICACCELHMDIRPLPGLTLSDLNELMTEALEPVSQRWPGRLSIDELHPPIPGYECPTDHHMVGVIEKLLGERTAVVNYCTEAPFIQQVCPTLVLGPGSINQAHQPDEFIDMAFIEPTRELIGQLVDHFCQQK
>NZ_CP045145.1|WP_002209489.1|4458125_4459130_-|N-acetyl-gamma-glutamyl-phosphate-reductase
MLNTLIVGASGYAGAELTAYLNRHPHMNITGLAVSAQSADAGKLLSDLHPQLKGILDLPLQPLVDVAQAAKGIDVVFLATAHEVSHDLAPQFLAAGCVVFDLSGAFRVRDAAFYSQYYGFEHQHPDWLDKAVYGLAEWQSEDIKQAQLIAVPGCYPTASQLALKPLVDGQLLNDAQWPVINAVSGVSGAGRKASMGNSFCEVSLQPYGLFTHRHQPEIVTHLGTPVIFTPHLGNFARGILATITCRLKAGVTAQNIADAYHHAYQNKPLVRLYQQGVPALKAVVGLPFCDIGFSVQGEHLIIVATEDNLLKGAAAQAVQCMNIRFGFPETQSLL
>NZ_CP045145.1|WP_002209488.1|4457183_4457957_-|acetylglutamate-kinase
MNPLVIKLGGVLLDSEEALERLFTALVTYREKHERPLVIMHGGGCLVDELMKRLALPVVKKNGLRVTPADQIDIITGALAGTANKTLLAWAVKHQINAVGLCLADGNTVTVTLLDAELGHVGKAQPGSAALVQTLLAAGYMPIISSIGITVEGQLMNVNADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTAQKAEQLIAQGIITDGMVVKVNAALDAARSLGRPVDIASWRHSEQLPALFNGVPIGTRISV
>NZ_CP045145.1|WP_002209487.1|4455643_4457017_-|argininosuccinate-lyase
MALWGGRFSQAADQRFKQFNDSLRFDYRLAEQDIIGSVAWSKALVTVGVLNADEQQQLEQALSVLLEEVQANPHAILASDAEDIHSWVETKLIDKVGDLGKKLHTGRSRNDQVATDLKLWCKFQITELQTAVQQLQQALVMTAEANQDAVMPGYTHLQRAQPVTFAHWCLAYVEMLSRDESRLQDTLKRLDVSPLGCGALAGTAYAIDREQLAGWLGFASATRNSLDSVSDRDHVLELLSDASIGMVHLSRFAEDLIFFNSGEAAFVDLSDRVTSGSSLMPQKKNPDALELIRGKCGRVQGALTGMTMTLKGLPLAYNKDMQEDKEGLFDALDTWLDCLHMAALVLDGIQVKRPRCKEAAEQGYANATELADYLVAKGVPFREAHHIVGEAVVEAIRQGKALEALALSDLQQFSSVIGDDVYPILALQSCLDKRVAKGGVSPQQVASAIAEAKARLF
>NZ_CP045145.1|WP_002209485.1|4452552_4455045_-|TonB-dependent-hemoglobin/transferrin/lactoferrin-family-receptor
MDNIIRDKKTIISVNKITTCILFALVTQGYSGQLAANTAETPTNNNDMALDKLNVEGKGNAHDSDWIYDEPRSVSEITREQLDNRPARHAADILEQTPGVYSSVSQQDPGLSINIRGIQDYGRVNMNIDGMRQNFMKSGHGQRNGSMYIDPEILSNVVIERGIFNGIGGAGAIGGIATFNTINASDFLAPEKELGGHIRAMTGDNGTRFIGSGALALGNPNGDILLAVSERNLKDYWPGNKGVLAGLRLYSPTRNVGDDLKNTKTLFTGYKMRSQLAKVGWNFEAGQRLEFSYLQTQIASPNASMLSEVLALSPSGKEITKIGWRNTSFTNVENRNIALDYRLNPEHISWLDATAKIYYVDTNDETDNANSLFKEYFWTQTRLKTRGLQLQNTNTFTPSDAHQIRLKYGLEWFSDKSEGYSTRKLIERTTPPGKRAITSTFAQLNYEYDDWLRLEGGLRYDQFRLKGNTWLHTRSFLQPYTFENPCDRRIHEQSEKPGSRCSSRRPATMRWDVDRCEQQLSPTLAMGVKPGLEWLEFFGSYGKSWRPPAMTEVLATGTAHGYSWVLPNPFVAAERARTWEAGFNIQQSNLFIEDDHFAAKVAYFDTRIANYINLELGKAKPKFGGDSFTDVAYVNNLLKTRFRGLEYQLSYDAGTFYTNINYTRMIGVNNVCSPYAWLGGLQSVKYKYVGKVEQIYAVENEVANNYVTCMNANVLFGSSAYLPGDRGSLTLGSRIFDRRLDFGTVIRYNKGYQDRSAQDENGNPLTAYVADWPKYIVYDLYASYKVTNNLILRSSIENITNRAYLVNYGDTLSFAPSRGRTIQGGFEYKF
>NZ_CP045145.1|WP_002209484.1|4451713_4452331_-|hemophore-HasA
MSTTIQYNSNYADYSISSYLREWANNFGDIDQAPAETKDRGSFSGSSTLFSGTQYAIGSSHSNPEGMIAEGDLKYSFMPQHTFHGQIDTLQFGKDLATNAGGPSAGKHLEKIDITFNELDLSGEFDSGKSMTENHQGDMHKSVRGLMKGNPDPMLEVMKAKGINVDTAFKDLSIASQYPDSGYMSDAPMVDTVGVVDCHDMLLAA
>NZ_CP045145.1|WP_002209483.1|4449739_4451548_-|type-I-secretion-system-permease/ATPase
MESCKTPGASSVPPTILSVLAGNKKILWGIGLFTAVINLLMLAPAIYMLQVYDRVLASANTMTLLMLTVLVLGVFVFIGLLEWVRSAVVIRLGTQIDMQLNQPVFNAAFAANLKGHNTPAAQALNDLTVLRQFATGNALFAFFDAPWFPLYLLVIFLLHPWLGMLAAAGAGILVVLAWLNQWICKKPLHDASIITSHATQQANANLRNADVIEAMGMLKALRERWLMQHANFLYQQNLASDKSSRVTAVAKSSRQALQSMMLGLGALLVIYNEITAGVMIAGSILIGRVLGPIDQLIAVWKQWSHARLAYQRLSQLLAQHPSSPTGMVLPAPQGKLNVTQLMACKPGTHIPVLHSINFELQPGDVLGILGPSGSGKSTLAKLLVASQPTFSGTVRLDSADLSRWDKTQLGEFIGYLPQNIQLFRGTVAENIARFGAIDTAKVVAAAQLADVHDLILHLPQGYDTPLGDDGEGLSGGQRQRIALARAMYGIPRLIVLDEPNASLDKEGEQALLASIIQLKQQGCTIVMITHKPELLSGSDYLLFLKNGQMDLFDRTQAVLQNIQGKDKPAVQPEAKILNSRSGWSNGVSYGIGPARTTSSPKP
>NZ_CP045145.1|WP_002209482.1|4448335_4449664_-|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit
MLPESVCYSVANANRQPPLQINSGRYLNIGGGLVVIGFIGFLLWAGLAPLDKGVAVTGLLVVAENRKVIQPLQGGRIQQLHVTEGDEIVSGQLLVTLDDTAIRNQRDNLQHQYLSALAQEARLTAEQNDLDVITFPQALLEHATQPAVERNIILQQQLLHHRRQAHLSEIARLSTQLTRHQARLDGLQAMRSNHQRQSNLFQQQLDSVQLLAKDGHIAKNKLLEMESQSTSLQARVEQSTSDIAEAHKLIDETEQHVLQRREQYQSENSEQLAKAQQNTQELVQRLNIAEYELSHTRIFAPVSGSVIALAQHTVGGVVSSGQALMEIVPSGQPLFVEAQLPVELIDKVAVGLPVDLNFSAFNQSNTPRLQGSVWRIGADRIQPPPTSPPYYPLTVAIDLDPTELAIRPGMAVDVFIRTGERSLLSYLFKPFTDRLHLALAEE
>NZ_CP045145.1|WP_002209481.1|4447467_4448271_-|energy-transducer-TonB
MNRLQQSSDKLIFWLVGALLACGIHIYALWWLSTASIPAIPTSYPAAIMMELSAEPEFMQNLPQNSVVGITQNIIEPAVEQRVNQPDDIVDLPTLPEQPEGQREITRKEPIKVKRPAENRATSRKPVNKETQESDSKQSSPAAAASAMLSGTSQQVAAAVNSDSSHRQQAQVSWKSRLQGHLMGFKRYPSSARKQQQQGTAMIRFVVDKNGYVSSVQLSHSSGTSALDREALAIIKRAQPLPKPPAELLSQGQITLSLPVDFNLKRK
>NZ_CP045145.1|WP_100067904.1|4464295_4465650_+|IS3-like-element-IS1661-family-transposase
MKHPFSTRLAAVQHYLSGKATLRETARQFSVGKSPLTRWIRAFRRQGEAGLEHHLSRTYTPEFRLCVVRYMMANRCSAADASAHFNIPNETIIQNWMKRYREGGKEALNPSKTGPTMPKDKYEHDSKPFSEMTHAELEKELEYLRAENAYPKKAESPERRKGTQGAAEKTRIVQALTAEHRLSCLLCAAKLARSTYYYHASKPDGVIDDYADAVKAIGALSRRHAQRYGYRRMTVALRKEGFTLNHKTVRKLMNQHGLLSLIRRKKYRSYRADGGRASDNLLARNFTSEISGLKWCTDVTEFRVGAQKLYLSVIQDLFNNEIISWHMSERAALILTCKTLEKALKVKGRKEGLMLHSDQGWHYRTPMWRSMLVEAGIRQSMSRKGNCLDNAVMENFFSHLKAEMYHRKKYDSATVLKRDIVEYIHYYNTERISLKTGGMSPAEYRTQVEKQ
>NZ_CP045145.1|WP_002208933.1|4465835_4466720_-|methylenetetrahydrofolate-reductase
MSFFHANQREALNQSLSELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSTLKPKFVSVTYGANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPTQLRDIAIDYWNSGIRHIVALRGDLPPNSGKPEMYACDLVGLLKDVGDFDISVAAYPEIHPEAKSAQADLINLKRKIDAGANRAITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTSIFDGLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>NZ_CP045145.1|WP_002208934.1|4466952_4469388_-|bifunctional-aspartate-kinase/homoserine-dehydrogenase-II
MNATAVAAAATGRQLHKFGGSSLADVKCYLRVANIMANYSHPGDLMVVSAAGSTTNQLISWLKLSQNDRLSAHQVQQSLRRYQHDLINGLLPPEMAEPLISEFIHDLERLAGLLDNKIDDVIYAEVVGHGEIWSARLMSALLNKLDMDAVWLDARRFLRAERAAQPQIDESRSYPLLQQLMAQHPHQRLVVTGFISRNEAGETVLLGRNGSDYSATQVGALAGAERVTIWSDVAGVYSADPRKVKDACLLPLLRLDEASELARLAAPVLHTRTLQPVSGSDIDLQLRCSYQPEQGSTRIERVLASGLGAKIVTSHDDVCLIELQIASHHDFSLAQKEIDLLLKRAQIKPLATGIHPDRNLLQLCYTSEVVNSALRVLEDAALPGKLSLREGLALVALVGAGVSKNPLHSHRFYQQLKDQPVEFVWQAEDGISMVAVLRLGPTEHLIQGLHQSLFRAEKRIGLMLFGKGNIGARWLELFAREQKSLSARSGFEFVLAGVVDSRRSLLSYDGLDASRTLAFYNDEAKEQDEESLFLWMRAHPFDDLVVLDVTASPSLAEQYLDFASYGFHVISANKLAGASSSNNYRQIRDAFAKTGRHWLYNATVGAGLPVNHTVRDLRDSGDSILAISGIFSGTLSWLFLQFDGSVPFTELVDQAWQQGLTEPDPRVDLSGQDVMRKLVILAREAGYDIEPNQVRVESLVPAGAESGSVDQFFENGEALNQQMIQRLEAAKEMGLVLRYVARFDANGKARVGVEAVRTDHPLASLLPCDNVFAIESRWYRDNPLVIRGPGAGRDVTAGAIQSDLNRLSQLL
>NZ_CP045145.1|WP_002208935.1|4470927_4471245_+|met-regulon-transcriptional-regulator-MetJ
MAEWNGEYVSPYAEHGKKSKQVKKITVSIPLKVLKILTDERTRRQVNNLRHATNSELLCEAFLHAFTGQPLPNDEDLRKERSDEIPEAAKILMRELGVDPDTWEY
>NZ_CP045145.1|WP_002208936.1|4471593_4472049_+|hypothetical-protein
MNPNYAKPSAAFTAASWSALLGGFVIFLIGLWNADMQLNERGYYFAVLILGLFSAVSLQKTVRDKLEGLAITSIYYGLCWVAFIVAVLLLCIGLWNATLALSEKGFYGVTFFMTLFGAIAVQKNTRDSAMSSDTESASLFKKVRDQLKAED
>NZ_CP045145.1|WP_002216737.1|4472609_4472825_-|50S-ribosomal-protein-L31
MKQGIHPKYEQVTASCSCGNVIKINSTVGHDLNLDVCGECHPFYTGKQRDVASGGRVDRFNKRFSVPGAKK
>NZ_CP045145.1|WP_002208938.1|4473067_4475266_+|primosomal-protein-N'
MSVVQVALPVPLARTFDYRLDSAMACPVVGARVSVPFGKRKAIGIVVGLSDTSTFPLEQLKTIDAILDNHSLFPPSLWRILCWATEYYHYPIGEVLFHALPILLRQGRPAQSAPLWQWFVTEQGRATPPESLKRAPKQQQALAALLQKPVYRHQVNEMALTESALQALRSKGLIDLRAQEATTTDWRHSFSVLGERLRLNTEQATAVGAIRSEDNQFAAWLLAGVTGSGKTEVYLSVLENILAQGRQALILVPEIGLTPQTIARFRERFNAPVEVLHSGLNDSERLSVWLRARSGEAAIVIGTRSALFTPFSRLGVIIIDEEHDSSYKQQEGWRYHARDLAVFRAREEGIPIVMGTATPALETLHNVQMGKYRQLTLTKRAGSAKPAAQHLLDLKGLPLKVGLSQPLLKQMKTHLQAGNQVILFLNRRGYAPALLCHECGWIAECQRCDHYYTLHQNHRQLRCHHCDSQRPVPQQCPKCGSTHLVSVGVGTEQLENELAPLFPETPITRIDRDTTSRKGSLEQYLADVHQGGARILIGTQMLAKGHHFPDVTLVALLDVDGALFSADFRSAERFAQLYTQVSGRAGRAGKQGEVILQTHHPEHPLLQILLQQGYDAFAKQALEERKSVFLPPYTSHIIVRSEDHDNQQSALFLQQLRNLLEASPLKDEALWIMGPVPALQAKRGGRFRWQLLLQHPSRQLLQRLIKTSQPLISTLPQARKVKWTIDVDPIDS
>NZ_CP045145.1|WP_002216730.1|4475618_4476647_+|DNA-binding-transcriptional-regulator-CytR
MENKKEFTMTTMKDVAEMAGVSTATVSRALMNPEKVSTVTRQKVEQAVLAVGYSPHALSRNIKRNESRTILVIVPDISDPFFADVIQGIEHAAAQQGYLILIGDCAQQTQQERTFVNLIITKQIDGMLLLGSNLPFDASKEEQRNLPPMVMANEFAPELELPTVHIDNLTAAYEAVNYLHELGHKRIACIAGPESLPLSHYRLQGYIQALRRNGITVDNDYIIRGDFSYEAGAQSFAALMELPHPPTAIFSHNDVMAVGAIWQAKQLGLRIPQDVSLVGFDDLKLSQFCDPPLTTVAQPRYQIGQQAMLLLLEQLQGHSVQSGSRLLDTELIIRESTAAPKH
>NZ_CP045145.1|WP_002208941.1|4476712_4477558_+|cell-division-protein-FtsN
MAQRDYVSRGRSGARRKSTSRKKRSAPIVSKTVMALAVALLVVFVGGLYFITHNKPGELPLLPNHDPRTGNGLPPKPEERWRYIKELENRQIGVPMPTEPSAGGEVNAKTELTNEQRQLLEQMQADMRQQPTQLSEVPYNQGMQQVPRSAVTIKPPATSVQPQPVTPPRQTTIPVQPQAPAPVRTPPAAPVTQAVTPPKVEKEKEKTQRWMVQCGSFKAVDQAESIRAQLAFAGIESRITSGGGWNRVVLGPYNSKAAADKALQRLQGAGQSGCIPLSVGG
>NZ_CP045145.1|WP_002208942.1|4477657_4478182_+|ATP-dependent-protease-subunit-HslV
MTTIVSVRRDGHVVIGGDGQVTLGNTVMKGNAKKVRRLYNNKVIAGFAGGTADAFTLFELFERKLEMHQGHLTKAAVELAKDWRTDRMLRKLEALLAVADETASLIITGNGDVVQPEDDLIAIGSGGPYAQSAARALLENTELGARDIVEKSLSIAGDICIYTNRFQTIEELTY

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP045145_2	2.4\|1268032\|32\|NZ_CP045145\|CRISPRCasFinder,CRT	1268032-1268063	32	NZ_CP045145.1	2420482-2420513	0	1.0
NZ_CP045145_3	3.1\|1877685\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877685-1877716	32	NZ_CP045145.1	2426048-2426079	0	1.0
NZ_CP045145_1	1.1\|542777\|51\|NZ_CP045145\|PILER-CR	542777-542827	51	NZ_CP045145.1	542664-542714	1	0.98

1. spacer 2.4|1268032|32|NZ_CP045145|CRISPRCasFinder,CRT matches to position: 2420482-2420513, mismatch: 0, identity: 1.0

agactgatgcaagatggcggtatgcgtacaga	CRISPR spacer
agactgatgcaagatggcggtatgcgtacaga	Protospacer
********************************

2. spacer 3.1|1877685|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to position: 2426048-2426079, mismatch: 0, identity: 1.0

ctgatgggtaactttaatcccaaattcttttt	CRISPR spacer
ctgatgggtaactttaatcccaaattcttttt	Protospacer
********************************

3. spacer 1.1|542777|51|NZ_CP045145|PILER-CR matches to position: 542664-542714, mismatch: 1, identity: 0.98

gtcaacgccactcattccacaaaatcccgcttcggcgggtttttgctttgg	CRISPR spacer
gtcaactccactcattccacaaaatcccgcttcggcgggtttttgctttgg	Protospacer
****** ********************************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP045145_2	2.4\|1268032\|32\|NZ_CP045145\|CRISPRCasFinder,CRT	1268032-1268063	32	MT374852	Yersinia phage vB_YpM_3, complete genome	12-43	0	1.0
NZ_CP045145_4	4.4\|2857395\|28\|NZ_CP045145\|PILER-CR	2857395-2857422	28	MH616963	CrAssphage sp. isolate ctbg_1, complete genome	86944-86971	5	0.821
NZ_CP045145_4	4.4\|2857395\|28\|NZ_CP045145\|PILER-CR	2857395-2857422	28	MT774386	CrAssphage cr110_1, complete genome	42860-42887	5	0.821
NZ_CP045145_3	3.4\|1877865\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877865-1877896	32	MK820641	Gordonia phage EnalisNailo, complete genome	34088-34119	6	0.812
NZ_CP045145_3	3.4\|1877865\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877865-1877896	32	MK878898	Gordonia phage Zameen, complete genome	34513-34544	6	0.812
NZ_CP045145_3	3.4\|1877865\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877865-1877896	32	MK919483	Gordonia phage Suscepit, complete genome	34514-34545	6	0.812
NZ_CP045145_3	3.4\|1877865\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877865-1877896	32	MK284520	Gordonia phage Lilas, complete genome	35799-35830	6	0.812
NZ_CP045145_3	3.4\|1877865\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877865-1877896	32	MK016492	Gordonia phage Bialota, complete genome	35265-35296	6	0.812
NZ_CP045145_3	3.4\|1877865\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877865-1877896	32	MK820642	Gordonia phage Polly, complete genome	33956-33987	6	0.812
NZ_CP045145_3	3.4\|1877865\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877865-1877896	32	NC_041883	Gordonia phage Attis, complete genome	31646-31677	6	0.812
NZ_CP045145_3	3.4\|1877865\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877865-1877896	32	MK814755	Gordonia phage Antonio, complete genome	34513-34544	6	0.812
NZ_CP045145_3	3.4\|1877865\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877865-1877896	32	MK875796	Gordonia phage Tayonia, complete genome	34513-34544	6	0.812
NZ_CP045145_3	3.4\|1877865\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877865-1877896	32	MK801734	Gordonia phage LordFarquaad, complete genome	31627-31658	6	0.812
NZ_CP045145_3	3.4\|1877865\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877865-1877896	32	MK433274	Gordonia phage Bradissa, complete genome	34554-34585	6	0.812
NZ_CP045145_3	3.4\|1877865\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877865-1877896	32	KU963257	Gordonia phage Kita, complete genome	34522-34553	6	0.812
NZ_CP045145_3	3.4\|1877865\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877865-1877896	32	NC_031251	Gordonia phage SoilAssassin, complete genome	31645-31676	6	0.812
NZ_CP045145_3	3.4\|1877865\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877865-1877896	32	NC_031097	Gordonia phage Zirinka, complete genome	35253-35284	6	0.812
NZ_CP045145_3	3.4\|1877865\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877865-1877896	32	NZ_CP005086	Sphingobium sp. TKS plasmid pTK2, complete sequence	138555-138586	6	0.812
NZ_CP045145_4	4.4\|2857395\|28\|NZ_CP045145\|PILER-CR	2857395-2857422	28	NZ_CP028934	Campylobacter jejuni strain FORC_083 plasmid pFORC_083_2, complete sequence	25851-25878	6	0.786
NZ_CP045145_3	3.4\|1877865\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877865-1877896	32	NZ_AP014579	Burkholderia sp. RPE67 plasmid p1, complete sequence	440819-440850	7	0.781
NZ_CP045145_3	3.4\|1877865\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877865-1877896	32	NC_016626	Burkholderia sp. YI23 plasmid byi_1p, complete sequence	282870-282901	7	0.781
NZ_CP045145_3	3.4\|1877865\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877865-1877896	32	KJ433975	Mycobacterium phage 40BC, complete genome	23231-23262	7	0.781
NZ_CP045145_3	3.4\|1877865\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877865-1877896	32	KJ433973	Mycobacterium phage 39HC, complete genome	23231-23262	7	0.781
NZ_CP045145_3	3.4\|1877865\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877865-1877896	32	NC_024145	Mycobacterium phage Hosp, complete genome	21427-21458	7	0.781
NZ_CP045145_3	3.5\|1877925\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877925-1877956	32	JF974294	Aeromonas phage pIS4-A genomic sequence	21965-21996	7	0.781
NZ_CP045145_3	3.5\|1877925\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877925-1877956	32	NC_021534	Vibrio phage pYD38-A genomic sequence	3299-3330	7	0.781
NZ_CP045145_3	3.7\|1878045\|32\|NZ_CP045145\|CRISPRCasFinder,CRT	1878045-1878076	32	CP049262	Cronobacter sakazakii strain CS-09 plasmid pCsaCS09b, complete sequence	69636-69667	7	0.781
NZ_CP045145_4	4.2\|2857391\|32\|NZ_CP045145\|CRISPRCasFinder,CRT	2857391-2857422	32	MH616963	CrAssphage sp. isolate ctbg_1, complete genome	86942-86973	7	0.781
NZ_CP045145_4	4.4\|2857395\|28\|NZ_CP045145\|PILER-CR	2857395-2857422	28	MK415408	CrAssphage GF1-2_000079F, complete genome	71106-71133	7	0.75
NZ_CP045145_3	3.1\|1877685\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877685-1877716	32	NZ_CP047125	Lactobacillus hilgardii strain FLUB plasmid unnamed4	1912-1943	8	0.75
NZ_CP045145_3	3.2\|1877745\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877745-1877776	32	NZ_CP024873	Leptospira mayottensis 200901116 plasmid p1_L200901116, complete sequence	14979-15010	8	0.75
NZ_CP045145_3	3.5\|1877925\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877925-1877956	32	NZ_CP029117	Escherichia coli strain AR435 plasmid unnamed4	112580-112611	8	0.75
NZ_CP045145_4	4.2\|2857391\|32\|NZ_CP045145\|CRISPRCasFinder,CRT	2857391-2857422	32	NZ_CP010358	Acinetobacter johnsonii XBB1 plasmid pXBB1-8, complete sequence	46720-46751	8	0.75
NZ_CP045145_4	4.2\|2857391\|32\|NZ_CP045145\|CRISPRCasFinder,CRT	2857391-2857422	32	NC_019694	Oscillatoria acuminata PCC 6304 plasmid pOSCIL6304.02, complete sequence	20911-20942	8	0.75
NZ_CP045145_2	2.3\|1267971\|33\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1267971-1268003	33	NZ_CP040366	Bacillus flexus isolate 1-2-1 plasmid punnamed3, complete sequence	923-955	9	0.727
NZ_CP045145_3	3.5\|1877925\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877925-1877956	32	MF679145	Escherichia coli plasmid pBJ114-96, complete sequence	37586-37617	9	0.719
NZ_CP045145_3	3.5\|1877925\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877925-1877956	32	NZ_KP453775	Klebsiella pneumoniae strain ST11 plasmid pKP12226, complete sequence	60831-60862	9	0.719
NZ_CP045145_3	3.5\|1877925\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877925-1877956	32	NZ_CP021340	Escherichia coli strain 95NR1 plasmid p95NR1A, complete sequence	67671-67702	9	0.719
NZ_CP045145_3	3.5\|1877925\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877925-1877956	32	NZ_CP021336	Escherichia coli strain 95JB1 plasmid p95JB1A, complete sequence	67672-67703	9	0.719
NZ_CP045145_3	3.5\|1877925\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877925-1877956	32	NZ_CP040920	Escherichia coli strain FC853_EC plasmid p853EC1, complete sequence	33435-33466	9	0.719
NZ_CP045145_3	3.5\|1877925\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877925-1877956	32	NZ_CP024832	Escherichia coli strain CREC-532 plasmid pCREC-532_2, complete sequence	33830-33861	9	0.719
NZ_CP045145_3	3.5\|1877925\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877925-1877956	32	NZ_CP024817	Escherichia coli strain CREC-629 plasmid pCREC-629_2, complete sequence	62769-62800	9	0.719
NZ_CP045145_3	3.5\|1877925\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877925-1877956	32	NZ_CP029117	Escherichia coli strain AR435 plasmid unnamed4	15616-15647	9	0.719
NZ_CP045145_3	3.5\|1877925\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877925-1877956	32	NZ_CP023961	Escherichia coli strain FDAARGOS_448 plasmid unnamed2, complete sequence	16858-16889	9	0.719
NZ_CP045145_3	3.5\|1877925\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877925-1877956	32	AP023222	Escherichia coli M505 plasmid pM505-b DNA, complete genome	93734-93765	9	0.719
NZ_CP045145_3	3.5\|1877925\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877925-1877956	32	AP023233	Escherichia coli YJ4 plasmid pYJ4-b DNA, complete genome	47570-47601	9	0.719
NZ_CP045145_3	3.5\|1877925\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877925-1877956	32	NZ_CP019075	Escherichia coli strain CRE1493 plasmid p1493-4, complete sequence	16520-16551	9	0.719
NZ_CP045145_3	3.5\|1877925\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877925-1877956	32	NZ_CP015837	Escherichia coli strain MS6198 plasmid pMS6198C, complete sequence	3287-3318	9	0.719
NZ_CP045145_3	3.5\|1877925\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877925-1877956	32	NZ_CP011063	Escherichia coli str. Sanji plasmid pSJ_98, complete sequence	37637-37668	9	0.719
NZ_CP045145_3	3.6\|1877985\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877985-1878016	32	NZ_CP031943	Nostoc sphaeroides strain Kutzing En plasmid p2, complete sequence	4006-4037	9	0.719
NZ_CP045145_4	4.2\|2857391\|32\|NZ_CP045145\|CRISPRCasFinder,CRT	2857391-2857422	32	MT774386	CrAssphage cr110_1, complete genome	42858-42889	9	0.719
NZ_CP045145_4	4.2\|2857391\|32\|NZ_CP045145\|CRISPRCasFinder,CRT	2857391-2857422	32	NZ_CP028934	Campylobacter jejuni strain FORC_083 plasmid pFORC_083_2, complete sequence	25849-25880	9	0.719
NZ_CP045145_3	3.4\|1877865\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877865-1877896	32	NZ_JX627581	Methylobacterium oryzae CBMB20 plasmid pMOC2, complete sequence	30496-30527	10	0.688
NZ_CP045145_3	3.2\|1877745\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877745-1877776	32	NC_007974	Cupriavidus metallidurans CH34 megaplasmid, complete sequence	815356-815387	11	0.656
NZ_CP045145_3	3.2\|1877745\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877745-1877776	32	NC_007974	Cupriavidus metallidurans CH34 megaplasmid, complete sequence	820287-820318	11	0.656
NZ_CP045145_3	3.2\|1877745\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877745-1877776	32	NZ_CP046333	Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3	2180994-2181025	11	0.656
NZ_CP045145_3	3.2\|1877745\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877745-1877776	32	NZ_CP046333	Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3	2185925-2185956	11	0.656

1. spacer 2.4|1268032|32|NZ_CP045145|CRISPRCasFinder,CRT matches to MT374852 (Yersinia phage vB_YpM_3, complete genome) position: , mismatch: 0, identity: 1.0

agactgatgcaagatggcggtatgcgtacaga	CRISPR spacer
agactgatgcaagatggcggtatgcgtacaga	Protospacer
********************************

2. spacer 4.4|2857395|28|NZ_CP045145|PILER-CR matches to MH616963 (CrAssphage sp. isolate ctbg_1, complete genome) position: , mismatch: 5, identity: 0.821

aagttctttttgtcagcatctttaataa	CRISPR spacer
ataatctttttatcagcatcttttataa	Protospacer
* . *******.*********** ****

3. spacer 4.4|2857395|28|NZ_CP045145|PILER-CR matches to MT774386 (CrAssphage cr110_1, complete genome) position: , mismatch: 5, identity: 0.821

aagttctttttgtcagcatctttaataa	CRISPR spacer
agtttctttttatcagcatcttcaatag	Protospacer
*. ********.**********.****.

4. spacer 3.4|1877865|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to MK820641 (Gordonia phage EnalisNailo, complete genome) position: , mismatch: 6, identity: 0.812

tcgcgaacgcgctcaggttcacggaatggcga-	CRISPR spacer
tcgcgagcgcgctcaggatcacggcg-gacgac	Protospacer
******.********** ****** . *.***

5. spacer 3.4|1877865|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to MK878898 (Gordonia phage Zameen, complete genome) position: , mismatch: 6, identity: 0.812

tcgcgaacgcgctcaggttcacggaatggcga-	CRISPR spacer
tcgcgagcgcgctcaggatcacggcg-gacgac	Protospacer
******.********** ****** . *.***

6. spacer 3.4|1877865|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to MK919483 (Gordonia phage Suscepit, complete genome) position: , mismatch: 6, identity: 0.812

tcgcgaacgcgctcaggttcacggaatggcga-	CRISPR spacer
tcgcgagcgcgctcaggatcacggcg-gacgac	Protospacer
******.********** ****** . *.***

7. spacer 3.4|1877865|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to MK284520 (Gordonia phage Lilas, complete genome) position: , mismatch: 6, identity: 0.812

tcgcgaacgcgctcaggttcacggaatggcga-	CRISPR spacer
tcgcgagcgcgctcaggatcacggcg-gacgac	Protospacer
******.********** ****** . *.***

8. spacer 3.4|1877865|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to MK016492 (Gordonia phage Bialota, complete genome) position: , mismatch: 6, identity: 0.812

tcgcgaacgcgctcaggttcacggaatggcga-	CRISPR spacer
tcgcgagcgcgctcaggatcacggcg-gacgac	Protospacer
******.********** ****** . *.***

9. spacer 3.4|1877865|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to MK820642 (Gordonia phage Polly, complete genome) position: , mismatch: 6, identity: 0.812

tcgcgaacgcgctcaggttcacggaatggcga-	CRISPR spacer
tcgcgagcgcgctcaggatcacggcg-gacgac	Protospacer
******.********** ****** . *.***

10. spacer 3.4|1877865|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to NC_041883 (Gordonia phage Attis, complete genome) position: , mismatch: 6, identity: 0.812

tcgcgaacgcgctcaggttcacggaatggcga-	CRISPR spacer
tcgcgagcgcgctcaggatcacggcg-gacgac	Protospacer
******.********** ****** . *.***

11. spacer 3.4|1877865|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to MK814755 (Gordonia phage Antonio, complete genome) position: , mismatch: 6, identity: 0.812

tcgcgaacgcgctcaggttcacggaatggcga-	CRISPR spacer
tcgcgagcgcgctcaggatcacggcg-gacgac	Protospacer
******.********** ****** . *.***

12. spacer 3.4|1877865|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to MK875796 (Gordonia phage Tayonia, complete genome) position: , mismatch: 6, identity: 0.812

tcgcgaacgcgctcaggttcacggaatggcga-	CRISPR spacer
tcgcgagcgcgctcaggatcacggcg-gacgac	Protospacer
******.********** ****** . *.***

13. spacer 3.4|1877865|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to MK801734 (Gordonia phage LordFarquaad, complete genome) position: , mismatch: 6, identity: 0.812

tcgcgaacgcgctcaggttcacggaatggcga-	CRISPR spacer
tcgcgagcgcgctcaggatcacggcg-gacgac	Protospacer
******.********** ****** . *.***

14. spacer 3.4|1877865|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to MK433274 (Gordonia phage Bradissa, complete genome) position: , mismatch: 6, identity: 0.812

tcgcgaacgcgctcaggttcacggaatggcga-	CRISPR spacer
tcgcgagcgcgctcaggatcacggcg-gacgac	Protospacer
******.********** ****** . *.***

15. spacer 3.4|1877865|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to KU963257 (Gordonia phage Kita, complete genome) position: , mismatch: 6, identity: 0.812

tcgcgaacgcgctcaggttcacggaatggcga-	CRISPR spacer
tcgcgagcgcgctcaggatcacggcg-gacgac	Protospacer
******.********** ****** . *.***

16. spacer 3.4|1877865|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to NC_031251 (Gordonia phage SoilAssassin, complete genome) position: , mismatch: 6, identity: 0.812

tcgcgaacgcgctcaggttcacggaatggcga-	CRISPR spacer
tcgcgagcgcgctcaggatcacggcg-gacgac	Protospacer
******.********** ****** . *.***

17. spacer 3.4|1877865|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to NC_031097 (Gordonia phage Zirinka, complete genome) position: , mismatch: 6, identity: 0.812

tcgcgaacgcgctcaggttcacggaatggcga-	CRISPR spacer
tcgcgagcgcgctcaggatcacggcg-gacgac	Protospacer
******.********** ****** . *.***

18. spacer 3.4|1877865|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP005086 (Sphingobium sp. TKS plasmid pTK2, complete sequence) position: , mismatch: 6, identity: 0.812

--tcgcgaacgcgctcaggttcacggaatggcga	CRISPR spacer
ggtcacga--tcgctcaggttcagggaaaggcga	Protospacer
  **.***   ************ **** *****

19. spacer 4.4|2857395|28|NZ_CP045145|PILER-CR matches to NZ_CP028934 (Campylobacter jejuni strain FORC_083 plasmid pFORC_083_2, complete sequence) position: , mismatch: 6, identity: 0.786

aagttctttttgtcagcatctttaataa	CRISPR spacer
actttctttttgtcagcgtctgtaatgt	Protospacer
*  **************.*** ****.

20. spacer 3.4|1877865|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP014579 (Burkholderia sp. RPE67 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.781

tcgcgaacgcgctcaggttcacggaatggcga----	CRISPR spacer
tcgcgaacgcgcccaggttcccg----agcgaggtg	Protospacer
************.******* **    .****

21. spacer 3.4|1877865|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to NC_016626 (Burkholderia sp. YI23 plasmid byi_1p, complete sequence) position: , mismatch: 7, identity: 0.781

tcgcgaacgcgctcaggttcacggaatggcga----	CRISPR spacer
tcgcgaacgcgcccaggttcccg----agcgaggtg	Protospacer
************.******* **    .****

22. spacer 3.4|1877865|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to KJ433975 (Mycobacterium phage 40BC, complete genome) position: , mismatch: 7, identity: 0.781

tcgcgaacgcgctcaggttcacggaatggcga-	CRISPR spacer
gcgcgaacgcgctcgggtacacgg-gcggcggg	Protospacer
 *************.*** ***** ..****.

23. spacer 3.4|1877865|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to KJ433973 (Mycobacterium phage 39HC, complete genome) position: , mismatch: 7, identity: 0.781

tcgcgaacgcgctcaggttcacggaatggcga-	CRISPR spacer
gcgcgaacgcgctcgggtacacgg-gcggcggg	Protospacer
 *************.*** ***** ..****.

24. spacer 3.4|1877865|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to NC_024145 (Mycobacterium phage Hosp, complete genome) position: , mismatch: 7, identity: 0.781

tcgcgaacgcgctcaggttcacggaatggcga-	CRISPR spacer
gcgcgaacgcgctcgggtacacgg-gcggcggg	Protospacer
 *************.*** ***** ..****.

25. spacer 3.5|1877925|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to JF974294 (Aeromonas phage pIS4-A genomic sequence) position: , mismatch: 7, identity: 0.781

atctgcgccaaagaaaatgccattcagataat	CRISPR spacer
atcaggcataaagcaaatgccattcaggtaat	Protospacer
*** *   .**** *************.****

26. spacer 3.5|1877925|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to NC_021534 (Vibrio phage pYD38-A genomic sequence) position: , mismatch: 7, identity: 0.781

atctgcgccaaagaaaatgccattcagataat	CRISPR spacer
atcaggcataaagcaaatgccattcaggtaat	Protospacer
*** *   .**** *************.****

27. spacer 3.7|1878045|32|NZ_CP045145|CRISPRCasFinder,CRT matches to CP049262 (Cronobacter sakazakii strain CS-09 plasmid pCsaCS09b, complete sequence) position: , mismatch: 7, identity: 0.781

atcatgaaagacattgttcgccagtcccctga	CRISPR spacer
atcatgaaagagattgttcgccagcgcgacgt	Protospacer
*********** ************. *  .*

28. spacer 4.2|2857391|32|NZ_CP045145|CRISPRCasFinder,CRT matches to MH616963 (CrAssphage sp. isolate ctbg_1, complete genome) position: , mismatch: 7, identity: 0.781

ttaagttctttttgtcagcatctttaataaat	CRISPR spacer
taataatctttttatcagcatcttttataatt	Protospacer
* * . *******.*********** **** *

29. spacer 4.4|2857395|28|NZ_CP045145|PILER-CR matches to MK415408 (CrAssphage GF1-2_000079F, complete genome) position: , mismatch: 7, identity: 0.75

aagttctttttgtcagcatctttaataa	CRISPR spacer
ataagacttttatcagcatctttaataa	Protospacer
* .   .****.****************

30. spacer 3.1|1877685|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP047125 (Lactobacillus hilgardii strain FLUB plasmid unnamed4) position: , mismatch: 8, identity: 0.75

ctgatgggtaactttaatcccaaattcttttt	CRISPR spacer
attttgaataactttaatcccaaaagctttta	Protospacer
 *  **..****************  *****

31. spacer 3.2|1877745|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024873 (Leptospira mayottensis 200901116 plasmid p1_L200901116, complete sequence) position: , mismatch: 8, identity: 0.75

tgttaaatcgtcgcctaaatttgtttgaccga	CRISPR spacer
tttagaatcgtcgcctcaacttgtttgagtaa	Protospacer
* * .*********** **.******** ..*

32. spacer 3.5|1877925|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029117 (Escherichia coli strain AR435 plasmid unnamed4) position: , mismatch: 8, identity: 0.75

atctgc-gccaaagaaaatgccattcagataat	CRISPR spacer
-taaacagttaaagaaactgccaatcagataat	Protospacer
 *  .* *..******* ***** *********

33. spacer 4.2|2857391|32|NZ_CP045145|CRISPRCasFinder,CRT matches to NZ_CP010358 (Acinetobacter johnsonii XBB1 plasmid pXBB1-8, complete sequence) position: , mismatch: 8, identity: 0.75

ttaagttctttttgtcagcatctttaataaat	CRISPR spacer
gtgccatattttcgtcagcatcattaataaat	Protospacer
 *.   * ****.********* *********

34. spacer 4.2|2857391|32|NZ_CP045145|CRISPRCasFinder,CRT matches to NC_019694 (Oscillatoria acuminata PCC 6304 plasmid pOSCIL6304.02, complete sequence) position: , mismatch: 8, identity: 0.75

ttaagttctttttgtcagcatctttaataaat	CRISPR spacer
ttgatgctcttttggcagcttctttaataaat	Protospacer
**.*  ...***** **** ************

35. spacer 2.3|1267971|33|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040366 (Bacillus flexus isolate 1-2-1 plasmid punnamed3, complete sequence) position: , mismatch: 9, identity: 0.727

ccgaaatcatcagatgtaattaagatttttgct	CRISPR spacer
aatggattatcagatgtaattaagtttttttcc	Protospacer
   ..**.**************** ***** *.

36. spacer 3.5|1877925|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to MF679145 (Escherichia coli plasmid pBJ114-96, complete sequence) position: , mismatch: 9, identity: 0.719

atctgcgccaaagaaaatgccattcagataat	CRISPR spacer
aaaacagttaaagaaactgccaatcagataat	Protospacer
*     *..******* ***** *********

37. spacer 3.5|1877925|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KP453775 (Klebsiella pneumoniae strain ST11 plasmid pKP12226, complete sequence) position: , mismatch: 9, identity: 0.719

atctgcgccaaagaaaatgccattcagataat	CRISPR spacer
aaaacagttaaagaaactgccaatcagataat	Protospacer
*     *..******* ***** *********

38. spacer 3.5|1877925|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021340 (Escherichia coli strain 95NR1 plasmid p95NR1A, complete sequence) position: , mismatch: 9, identity: 0.719

atctgcgccaaagaaaatgccattcagataat	CRISPR spacer
aaaacagttaaagaaactgccaatcagataat	Protospacer
*     *..******* ***** *********

39. spacer 3.5|1877925|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021336 (Escherichia coli strain 95JB1 plasmid p95JB1A, complete sequence) position: , mismatch: 9, identity: 0.719

atctgcgccaaagaaaatgccattcagataat	CRISPR spacer
aaaacagttaaagaaactgccaatcagataat	Protospacer
*     *..******* ***** *********

40. spacer 3.5|1877925|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040920 (Escherichia coli strain FC853_EC plasmid p853EC1, complete sequence) position: , mismatch: 9, identity: 0.719

atctgcgccaaagaaaatgccattcagataat	CRISPR spacer
aaaacagttaaagaaactgccaatcagataat	Protospacer
*     *..******* ***** *********

41. spacer 3.5|1877925|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024832 (Escherichia coli strain CREC-532 plasmid pCREC-532_2, complete sequence) position: , mismatch: 9, identity: 0.719

atctgcgccaaagaaaatgccattcagataat	CRISPR spacer
aaaacagttaaagaaactgccaatcagataat	Protospacer
*     *..******* ***** *********

42. spacer 3.5|1877925|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024817 (Escherichia coli strain CREC-629 plasmid pCREC-629_2, complete sequence) position: , mismatch: 9, identity: 0.719

atctgcgccaaagaaaatgccattcagataat	CRISPR spacer
aaaacagttaaagaaactgccaatcagataat	Protospacer
*     *..******* ***** *********

43. spacer 3.5|1877925|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029117 (Escherichia coli strain AR435 plasmid unnamed4) position: , mismatch: 9, identity: 0.719

atctgcgccaaagaaaatgccattcagataat	CRISPR spacer
aaaacagttaaagaaactgccaatcagataat	Protospacer
*     *..******* ***** *********

44. spacer 3.5|1877925|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP023961 (Escherichia coli strain FDAARGOS_448 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

atctgcgccaaagaaaatgccattcagataat	CRISPR spacer
aaaacagttaaagaaactgccaatcagataat	Protospacer
*     *..******* ***** *********

45. spacer 3.5|1877925|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to AP023222 (Escherichia coli M505 plasmid pM505-b DNA, complete genome) position: , mismatch: 9, identity: 0.719

atctgcgccaaagaaaatgccattcagataat	CRISPR spacer
aaaacagttaaagaaactgccaatcagataat	Protospacer
*     *..******* ***** *********

46. spacer 3.5|1877925|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to AP023233 (Escherichia coli YJ4 plasmid pYJ4-b DNA, complete genome) position: , mismatch: 9, identity: 0.719

atctgcgccaaagaaaatgccattcagataat	CRISPR spacer
aaaacagttaaagaaactgccaatcagataat	Protospacer
*     *..******* ***** *********

47. spacer 3.5|1877925|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019075 (Escherichia coli strain CRE1493 plasmid p1493-4, complete sequence) position: , mismatch: 9, identity: 0.719

atctgcgccaaagaaaatgccattcagataat	CRISPR spacer
aaaacagttaaagaaactgccaatcagataat	Protospacer
*     *..******* ***** *********

48. spacer 3.5|1877925|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015837 (Escherichia coli strain MS6198 plasmid pMS6198C, complete sequence) position: , mismatch: 9, identity: 0.719

atctgcgccaaagaaaatgccattcagataat	CRISPR spacer
aaaacagttaaagaaactgccaatcagataat	Protospacer
*     *..******* ***** *********

49. spacer 3.5|1877925|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP011063 (Escherichia coli str. Sanji plasmid pSJ_98, complete sequence) position: , mismatch: 9, identity: 0.719

atctgcgccaaagaaaatgccattcagataat	CRISPR spacer
aaaacagttaaagaaactgccaatcagataat	Protospacer
*     *..******* ***** *********

50. spacer 3.6|1877985|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP031943 (Nostoc sphaeroides strain Kutzing En plasmid p2, complete sequence) position: , mismatch: 9, identity: 0.719

aactactagaagcttgcccatcttaccttttc	CRISPR spacer
taccactaaaagcttgcccatctttctcataa	Protospacer
 **.****.*************** *.. *

51. spacer 4.2|2857391|32|NZ_CP045145|CRISPRCasFinder,CRT matches to MT774386 (CrAssphage cr110_1, complete genome) position: , mismatch: 9, identity: 0.719

ttaagttctttttgtcagcatctttaataaat	CRISPR spacer
caagtttctttttatcagcatcttcaatagca	Protospacer
. *. ********.**********.****.

52. spacer 4.2|2857391|32|NZ_CP045145|CRISPRCasFinder,CRT matches to NZ_CP028934 (Campylobacter jejuni strain FORC_083 plasmid pFORC_083_2, complete sequence) position: , mismatch: 9, identity: 0.719

ttaagttctttttgtcagcatctttaataaat	CRISPR spacer
taactttctttttgtcagcgtctgtaatgtgc	Protospacer
* *  **************.*** ****. ..

53. spacer 3.4|1877865|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to NZ_JX627581 (Methylobacterium oryzae CBMB20 plasmid pMOC2, complete sequence) position: , mismatch: 10, identity: 0.688

tcgcgaacgcgctcaggttcacggaatggcga	CRISPR spacer
acgcgaatgcgctgaggttcacggctcgttag	Protospacer
 ******.***** **********  .* ...

54. spacer 3.2|1877745|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to NC_007974 (Cupriavidus metallidurans CH34 megaplasmid, complete sequence) position: , mismatch: 11, identity: 0.656

tgttaaatcgtcgcctaaatttgtttgaccga	CRISPR spacer
cagcggctccttgcctaaatttgtttgaccac	Protospacer
.. ... ** *.******************.

55. spacer 3.2|1877745|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to NC_007974 (Cupriavidus metallidurans CH34 megaplasmid, complete sequence) position: , mismatch: 11, identity: 0.656

tgttaaatcgtcgcctaaatttgtttgaccga	CRISPR spacer
cagcggctccttgcctaaatttgtttgaccac	Protospacer
.. ... ** *.******************.

56. spacer 3.2|1877745|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046333 (Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3) position: , mismatch: 11, identity: 0.656

tgttaaatcgtcgcctaaatttgtttgaccga	CRISPR spacer
cagcggctccttgcctaaatttgtttgaccac	Protospacer
.. ... ** *.******************.

57. spacer 3.2|1877745|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046333 (Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3) position: , mismatch: 11, identity: 0.656

tgttaaatcgtcgcctaaatttgtttgaccga	CRISPR spacer
cagcggctccttgcctaaatttgtttgaccac	Protospacer
.. ... ** *.******************.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

461888 : 524325

uncultured_Mediterranean_phage(18.18%)

protease,tail,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002210082.1\|461888_463334_+\|protease	metalloprotease TldD	NA	NA	NA	NA
WP_002210083.1\|463536_466395_-	RHS repeat protein	NA	NA	NA	NA
WP_002228695.1\|466419_469260_-	RHS repeat protein	NA	NA	NA	NA
WP_002210086.1\|469460_469820_-	DUF2570 domain-containing protein	NA	NA	NA	NA
WP_002210087.1\|469816_470218_-	M15 family metallopeptidase	A0A249XWK9	Proteus_phage	3.6e-36	61.0
WP_002214300.1\|470230_470533_-	hypothetical protein	NA	NA	NA	NA
WP_002210089.1\|470666_475157_-	toxin	NA	NA	NA	NA
WP_002220204.1\|475213_478807_-\|tail	phage tail tape measure protein	NA	NA	NA	NA
WP_002210090.1\|478847_481349_-	toxin	NA	NA	NA	NA
WP_002214297.1\|481584_482451_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002210092.1\|482711_483623_-	HTH-type transcriptional activator AaeR	NA	NA	NA	NA
WP_002210093.1\|483925_484129_+	AaeX family protein	NA	NA	NA	NA
WP_002210094.1\|484136_485072_+	p-hydroxybenzoic acid efflux pump subunit AaeA	NA	NA	NA	NA
WP_002210095.1\|485073_487029_+	p-hydroxybenzoic acid efflux pump subunit AaeB	NA	NA	NA	NA
WP_002214288.1\|488958_489432_+	ribonuclease Ba	NA	NA	NA	NA
WP_002210098.1\|489436_489718_+	ribonuclease inhibitor	NA	NA	NA	NA
WP_002210099.1\|489829_490378_-	ribosome-associated protein	NA	NA	NA	NA
WP_002210100.1\|490558_491899_+\|protease	metalloprotease PmbA	NA	NA	NA	NA
WP_011055205.1\|492147_492792_+	hypothetical protein	A0A1B0VBK8	Salmonella_phage	3.4e-52	49.0
WP_002210102.1\|492999_493386_+	cytochrome b562	NA	NA	NA	NA
WP_002210103.1\|493609_494020_-	nucleoside diphosphate kinase regulator	NA	NA	NA	NA
WP_002210104.1\|494372_496040_-	alpha,alpha-phosphotrehalase	NA	NA	NA	NA
WP_002215779.1\|496134_497550_-	PTS trehalose transporter subunit IIBC	NA	NA	NA	NA
WP_002210106.1\|497960_498914_-	HTH-type transcriptional regulator TreR	NA	NA	NA	NA
WP_002210107.1\|499147_499624_-	hypothetical protein	NA	NA	NA	NA
WP_002210109.1\|499922_500309_-	2-iminobutanoate/2-iminopropanoate deaminase	NA	NA	NA	NA
WP_002210110.1\|500446_500911_-	aspartate carbamoyltransferase regulatory subunit	NA	NA	NA	NA
WP_002210111.1\|500922_501858_-	aspartate carbamoyltransferase	M1HWF9	Paramecium_bursaria_Chlorella_virus	1.5e-48	38.5
WP_002210112.1\|502195_502468_-	PTS phosphocarrier protein NPr	NA	NA	NA	NA
WP_002210113.1\|502464_503319_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	3.2e-05	30.0
WP_002213952.1\|503624_504107_-	PTS IIA-like nitrogen regulatory protein PtsN	NA	NA	NA	NA
WP_002210115.1\|504535_505969_-	RNA polymerase factor sigma-54	NA	NA	NA	NA
WP_002210116.1\|506030_506756_-	LPS export ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.4e-22	28.4
WP_002210117.1\|506762_507308_-	lipopolysaccharide ABC transporter substrate-binding protein LptA	NA	NA	NA	NA
WP_002218352.1\|507291_507855_-	LPS export ABC transporter periplasmic protein LptC	NA	NA	NA	NA
WP_002228203.1\|507851_508415_-	3-deoxy-manno-octulosonate-8-phosphatase KdsC	A0A140XBD6	Dickeya_phage	9.6e-59	83.0
WP_002210119.1\|508663_509650_-	arabinose-5-phosphate isomerase KdsD	A0A2P0VNK5	Tetraselmis_virus	6.0e-40	30.8
WP_002210120.1\|509760_510735_-	calcium/sodium antiporter	NA	NA	NA	NA
WP_002210121.1\|510999_511818_+	phospholipid ABC transporter ATP-binding protein MlaF	G3M9Y6	Bacillus_virus	2.2e-19	31.7
WP_002210122.1\|512035_512818_+	lipid asymmetry maintenance ABC transporter permease subunit MlaE	NA	NA	NA	NA
WP_002210123.1\|512822_513380_+	outer membrane lipid asymmetry maintenance protein MlaD	NA	NA	NA	NA
WP_002210124.1\|513392_514016_+	phospholipid-binding protein MlaC	NA	NA	NA	NA
WP_002210125.1\|514051_514354_+	lipid asymmetry maintenance protein MlaB	NA	NA	NA	NA
WP_002210126.1\|514500_514755_+	BolA family iron metabolism protein IbaG	NA	NA	NA	NA
WP_002210127.1\|514908_516171_+	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_002210128.1\|516351_517440_-	outer membrane-stress sensor serine endopeptidase DegS	A0A1B1IRD3	uncultured_Mediterranean_phage	2.1e-09	31.8
WP_002213775.1\|517665_518124_+\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002218066.1\|518240_519614_-\|protease	serine endoprotease DegQ	A0A1B1IT49	uncultured_Mediterranean_phage	7.4e-20	28.2
WP_002210130.1\|519884_520289_-	DUF1043 family protein	NA	NA	NA	NA
WP_002210131.1\|520512_521640_+	cell division protein ZapE	NA	NA	NA	NA
WP_002210132.1\|521953_522382_+	50S ribosomal protein L13	NA	NA	NA	NA
WP_002210133.1\|522396_522789_+	30S ribosomal protein S9	NA	NA	NA	NA
WP_002230558.1\|522785_522983_-	hypothetical protein	NA	NA	NA	NA
WP_002210135.1\|523162_523804_+	stringent starvation protein A	NA	NA	NA	NA
WP_002216203.1\|523809_524325_+\|protease	ClpXP protease specificity-enhancing factor	A0A1S5R3H3	Pseudomonas_phage	3.6e-28	55.6

DBSCAN-SWA_2

678930 : 741024

Escherichia_phage(14.29%)

protease,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002209144.1\|678930_680166_-\|tRNA	tRNA epoxyqueuosine(34) reductase QueG	NA	NA	NA	NA
WP_002209145.1\|680164_681679_+	bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase	NA	NA	NA	NA
WP_002209146.1\|681689_682160_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	NA	NA	NA	NA
WP_002232017.1\|682167_684081_+	N-acetylmuramoyl-L-alanine amidase AmiB	M1HNA7	Bacillus_virus	2.1e-28	28.2
WP_002209148.1\|684096_686004_+	DNA mismatch repair endonuclease MutL	A0A1B2LRQ5	Wolbachia_phage	4.3e-58	41.3
WP_002209149.1\|685996_686938_+\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_002209151.1\|687053_687359_+	RNA chaperone Hfq	NA	NA	NA	NA
WP_002209152.1\|687457_688744_+	GTPase HflX	NA	NA	NA	NA
WP_002209154.1\|688984_690244_+\|protease	FtsH protease activity modulator HflK	NA	NA	NA	NA
WP_002209155.1\|690247_691252_+\|protease	protease modulator HflC	NA	NA	NA	NA
WP_002217227.1\|691423_691624_+	DUF2065 domain-containing protein	NA	NA	NA	NA
WP_002209157.1\|691723_693022_+	adenylosuccinate synthase	W5S5V7	Pithovirus	1.3e-66	35.4
WP_002217229.1\|693390_693816_+	nitric oxide-sensing transcriptional repressor NsrR	NA	NA	NA	NA
WP_002209159.1\|694056_696591_+	ribonuclease R	Q0GXV6	Lactococcus_phage	2.5e-66	33.3
WP_002209161.1\|696709_697450_+	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	NA	NA	NA	NA
WP_002353634.1\|697869_699501_+	isovaleryl-CoA dehydrogenase	NA	NA	NA	NA
WP_002215294.1\|699572_699884_-	biofilm peroxide resistance protein BsmA	NA	NA	NA	NA
WP_002228674.1\|700068_700173_+	hypothetical protein	NA	NA	NA	NA
WP_001297096.1\|700223_701003_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_000255944.1\|701002_702025_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_002210152.1\|702081_702783_+	esterase	NA	NA	NA	NA
WP_002210153.1\|703149_703542_+	30S ribosomal protein S6	NA	NA	NA	NA
WP_002430134.1\|703550_703868_+	primosomal replication protein N	NA	NA	NA	NA
WP_002210155.1\|703872_704100_+	30S ribosomal protein S18	NA	NA	NA	NA
WP_002210156.1\|704139_704592_+	50S ribosomal protein L9	NA	NA	NA	NA
WP_002213775.1\|704787_705246_+\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002210157.1\|705367_705823_-	DUF3757 domain-containing protein	NA	NA	NA	NA
WP_002210158.1\|705962_706703_-	peptidoglycan-binding protein LysM	NA	NA	NA	NA
WP_002228198.1\|707045_707666_+	peptidyl-prolyl cis-trans isomerase	NA	NA	NA	NA
WP_002210159.1\|707763_708429_-	iron-sulfur cluster repair protein YtfE	NA	NA	NA	NA
WP_002210160.1\|708583_710554_-	bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase	NA	NA	NA	NA
WP_002220539.1\|710988_711729_+	3'(2'),5'-bisphosphate nucleotidase CysQ	NA	NA	NA	NA
WP_002210162.1\|711731_712295_-	YtfJ family protein	NA	NA	NA	NA
WP_002210163.1\|712630_712843_+	DUF1107 domain-containing protein	NA	NA	NA	NA
WP_002210164.1\|712950_714282_-	HlyC/CorC family transporter	NA	NA	NA	NA
WP_002210165.1\|714559_715198_-	peptide-methionine (S)-S-oxide reductase MsrA	NA	NA	NA	NA
WP_002210166.1\|715472_717209_+	outer membrane protein assembly factor	NA	NA	NA	NA
WP_002210167.1\|717205_721123_+	hypothetical protein	NA	NA	NA	NA
WP_002210168.1\|721125_721482_+	gamma-glutamylcyclotransferase	NA	NA	NA	NA
WP_002210169.1\|721599_722127_-	inorganic diphosphatase	A0A2H4J8U1	uncultured_Caudovirales_phage	9.3e-56	62.7
WP_002213775.1\|722366_722825_-\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002216946.1\|723037_724051_-	class 1 fructose-bisphosphatase	A0A1V0SKX4	Klosneuvirus	3.0e-71	45.8
WP_002210171.1\|724221_725604_+	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase	NA	NA	NA	NA
WP_002210172.1\|725899_726163_-	peroxide/acid stress response protein YhcN	NA	NA	NA	NA
WP_002210173.1\|726551_727022_-	transcriptional regulator ArgR	NA	NA	NA	NA
WP_002210174.1\|727485_728424_+	malate dehydrogenase	NA	NA	NA	NA
WP_002210175.1\|728857_729133_-	transcriptional regulator	A0A2I7S995	Vibrio_phage	1.1e-18	64.2
WP_002210176.1\|729316_729664_+	putative DNA-binding transcriptional regulator	A0A0M3LPN5	Mannheimia_phage	7.3e-09	45.2
WP_002210177.1\|729760_730732_-	octaprenyl diphosphate synthase	A0A1V0SE37	Indivirus	6.0e-08	27.6
WP_002210178.1\|730991_731303_+	50S ribosomal protein L21	NA	NA	NA	NA
WP_002210179.1\|731322_731580_+	50S ribosomal protein L27	NA	NA	NA	NA
WP_002210180.1\|731667_732654_+	DMT family transporter	NA	NA	NA	NA
WP_002210181.1\|732654_733827_+	Obg family GTPase CgtA	NA	NA	NA	NA
WP_002210182.1\|733921_734989_-	two-component system sensor histidine kinase PmrB	W8CYF6	Bacillus_phage	4.7e-06	21.9
WP_002210183.1\|734985_735648_-	two-component system response regulator PmrA	W8CYM9	Bacillus_phage	8.4e-30	35.5
WP_002217314.1\|735653_737102_-	serine-type D-Ala-D-Ala carboxypeptidase	NA	NA	NA	NA
WP_002210184.1\|737359_737836_+	transcription elongation factor GreA	NA	NA	NA	NA
WP_002210185.1\|737963_738257_-	ribosome assembly RNA-binding protein YhbY	NA	NA	NA	NA
WP_002228196.1\|738403_739033_+	23S rRNA (uridine(2552)-2'-O)-methyltransferase RlmE	NA	NA	NA	NA
WP_002228195.1\|739089_741024_+\|protease	ATP-dependent zinc metalloprotease FtsH	G8DDJ2	Micromonas_pusilla_virus	4.4e-119	44.5

DBSCAN-SWA_3

1204334 : 1249001

uncultured_virus(30.0%)

protease,integrase,transposase,tRNA

attL 1225050:1225109|attR 1248978:1250293

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002208581.1\|1204334_1204814_-\|tRNA	Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK	NA	NA	NA	NA
WP_002208580.1\|1205077_1205887_-	hypothetical protein	NA	NA	NA	NA
WP_002223301.1\|1206407_1209293_-	copper-exporting P-type ATPase CopA	A0A218MNH6	uncultured_virus	1.0e-111	36.8
WP_002208578.1\|1209499_1209919_+	Cu(I)-responsive transcriptional regulator	NA	NA	NA	NA
WP_002208577.1\|1210027_1210477_-	NfeD family protein	NA	NA	NA	NA
WP_002208576.1\|1210479_1211394_-	SPFH/Band 7/PHB domain protein	NA	NA	NA	NA
WP_002208575.1\|1211588_1212458_-	co-chaperone YbbN	NA	NA	NA	NA
WP_002208574.1\|1212534_1213311_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_002208573.1\|1213697_1214333_-\|protease	multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1	NA	NA	NA	NA
WP_002208572.1\|1214303_1214990_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.6e-31	34.2
WP_002208571.1\|1214986_1217416_+	ABC transporter permease	NA	NA	NA	NA
WP_002208570.1\|1217459_1218524_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_002208569.1\|1218520_1219045_-	5-(carboxyamino)imidazole ribonucleotide mutase	NA	NA	NA	NA
WP_002208568.1\|1219340_1220063_-	UDP-2,3-diacylglucosamine diphosphatase	NA	NA	NA	NA
WP_002208567.1\|1220073_1220568_-	peptidylprolyl isomerase B	NA	NA	NA	NA
WP_002222677.1\|1220778_1222164_+\|tRNA	cysteine--tRNA ligase	A0A0G2Y344	Acanthamoeba_polyphaga_mimivirus	2.2e-40	28.5
WP_002213775.1\|1222510_1222969_+\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002209775.1\|1223115_1223328_-	ribosome-associated protein YbcJ	NA	NA	NA	NA
WP_002209774.1\|1223342_1224209_-	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	2.2e-30	34.1
WP_002215270.1\|1224563_1224746_-	AlpA family phage regulatory protein	NA	NA	NA	NA
1225050:1225109	attL	NA	NA	NA	NA
WP_002209743.1\|1225085_1226294_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_050882058.1\|1226327_1226528_-	hypothetical protein	NA	NA	NA	NA
WP_002228356.1\|1226641_1227139_-	hypothetical protein	NA	NA	NA	NA
WP_002215266.1\|1227274_1227613_-	hypothetical protein	NA	NA	NA	NA
WP_079866998.1\|1227695_1227974_-\|integrase	tyrosine-type recombinase/integrase	A0A192Y6Q1	Salmonella_phage	4.2e-31	73.5
WP_002354559.1\|1228185_1228392_+	hypothetical protein	NA	NA	NA	NA
WP_002209770.1\|1228791_1229394_+	CDP-alcohol phosphatidyltransferase family protein	NA	NA	NA	NA
WP_002209769.1\|1229386_1230316_+	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_002209768.1\|1230325_1230958_+	1-acyl-sn-glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
WP_002209767.1\|1230954_1232718_+	bifunctional alpha/beta hydrolase/class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_002209766.1\|1232710_1234030_+	phosphatase PAP2/dual specificity phosphatase family protein	NA	NA	NA	NA
WP_002209765.1\|1234011_1234413_+	hypothetical protein	NA	NA	NA	NA
WP_002215253.1\|1234509_1234815_+	hypothetical protein	NA	NA	NA	NA
WP_001297096.1\|1235181_1235961_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_000255944.1\|1235960_1236983_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_002209764.1\|1237076_1237970_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002209763.1\|1238024_1239014_-	aldo/keto reductase	NA	NA	NA	NA
WP_002209762.1\|1239039_1239891_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	1.2e-49	41.1
WP_002209759.1\|1240363_1241992_+	hypothetical protein	NA	NA	NA	NA
WP_002209758.1\|1242070_1244452_-	glycosyl hydrolase	NA	NA	NA	NA
WP_002209757.1\|1244610_1245141_-	GDYXXLXY domain-containing protein	NA	NA	NA	NA
WP_002209756.1\|1245133_1247341_-	DUF4401 domain-containing protein	NA	NA	NA	NA
WP_002209743.1\|1247792_1249001_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
1248978:1250293	attR	NA	NA	NA	NA

DBSCAN-SWA_4

1624093 : 1693098

Escherichia_phage(38.46%)

plate,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002213759.1\|1624093_1624552_+\|transposase	IS200/IS605-like element IS1541A family transposase	NA	NA	NA	NA
WP_002208491.1\|1624694_1625204_-	PTS glucose transporter subunit IIA	NA	NA	NA	NA
WP_002208490.1\|1625252_1626980_-	phosphoenolpyruvate-protein phosphotransferase PtsI	A0A1V0SGR7	Hokovirus	3.0e-18	33.3
WP_002208488.1\|1627028_1627286_-	phosphocarrier protein Hpr	NA	NA	NA	NA
WP_002222180.1\|1627784_1628753_-	cysteine synthase A	A0A1X9I5F1	Streptococcus_phage	4.8e-74	51.8
WP_002213487.1\|1628909_1629644_-	sulfate transporter CysZ	NA	NA	NA	NA
WP_002227089.1\|1629892_1630879_+	cell division protein ZipA	NA	NA	NA	NA
WP_002213368.1\|1630969_1632982_+	NAD-dependent DNA ligase LigA	A0A0K2QQN8	Ralstonia_phage	1.7e-142	42.2
WP_002213369.1\|1633001_1633217_+	DUF3820 family protein	NA	NA	NA	NA
WP_002213372.1\|1633317_1633665_-	hypothetical protein	NA	NA	NA	NA
WP_002213374.1\|1633796_1634402_-	nucleotidyltransferase family protein	NA	NA	NA	NA
WP_002213775.1\|1635115_1635574_-\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002222185.1\|1635766_1637182_-\|tRNA	glutamate--tRNA ligase	NA	NA	NA	NA
WP_002211622.1\|1638415_1639600_-	NupC/NupG family nucleoside CNT transporter	NA	NA	NA	NA
WP_002211621.1\|1640050_1641280_+	divalent metal cation transporter	NA	NA	NA	NA
WP_002354622.1\|1641372_1641687_-	DUF2502 domain-containing protein	NA	NA	NA	NA
WP_002211618.1\|1641956_1642946_-	glyceraldehyde 3-phosphate reductase	NA	NA	NA	NA
WP_002211617.1\|1643081_1643960_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_152329029.1\|1644062_1644548_+	multidrug/biocide efflux PACE transporter	NA	NA	NA	NA
WP_002211615.1\|1644728_1645700_+	glucokinase	NA	NA	NA	NA
WP_002211614.1\|1645777_1647025_-	DUF1479 domain-containing protein	NA	NA	NA	NA
WP_002211613.1\|1647290_1648526_+	alanine transaminase	NA	NA	NA	NA
WP_002211611.1\|1648789_1649314_+	cytochrome b	A0A0U2QLA7	Escherichia_phage	9.3e-24	47.1
WP_002211610.1\|1649408_1649840_-	hypothetical protein	Q7Y3V7	Yersinia_phage	2.4e-25	48.2
WP_002215847.1\|1650429_1651101_+	lipoprotein	NA	NA	NA	NA
WP_002215846.1\|1651127_1651484_+	DUF4810 domain-containing protein	NA	NA	NA	NA
WP_002211607.1\|1651480_1652137_+	DUF799 domain-containing protein	NA	NA	NA	NA
WP_002211606.1\|1652382_1652952_-	4Fe-4S binding protein	NA	NA	NA	NA
WP_002228419.1\|1652948_1653545_-	molecular chaperone	A0A077SLS7	Escherichia_phage	9.2e-44	49.2
WP_002211604.1\|1654026_1654803_-	dimethyl sulfoxide reductase anchor subunit	A0A077SK59	Escherichia_phage	3.9e-42	41.4
WP_002211603.1\|1654804_1655422_-	dimethylsulfoxide reductase subunit B	A0A077SL61	Escherichia_phage	1.1e-87	68.3
WP_002211602.1\|1655433_1657860_-	dimethyl sulfoxide reductase subunit A	A0A077SK27	Escherichia_phage	1.1e-255	54.4
WP_002211601.1\|1658690_1659539_+	DUF4225 domain-containing protein	NA	NA	NA	NA
WP_002354621.1\|1659768_1660248_-	Hcp family type VI secretion system effector	NA	NA	NA	NA
WP_002211599.1\|1660714_1661239_+	DUF2127 domain-containing protein	NA	NA	NA	NA
WP_002211598.1\|1661311_1662361_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.9e-21	32.4
WP_002215840.1\|1662357_1663944_-	iron ABC transporter permease	NA	NA	NA	NA
WP_002211596.1\|1663999_1665019_-	iron ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002211594.1\|1665347_1666442_+	lytic murein transglycosylase B	NA	NA	NA	NA
WP_002211590.1\|1667707_1668310_+	LuxR family transcriptional regulator	NA	NA	NA	NA
WP_002215321.1\|1668667_1669150_-	DcrB-related protein	NA	NA	NA	NA
WP_002211588.1\|1669146_1670829_-	OmpA family protein	NA	NA	NA	NA
WP_002224806.1\|1670829_1671531_-	hypothetical protein	NA	NA	NA	NA
WP_002211586.1\|1671527_1672865_-	glycosyl transferase	A0A292GJ55	Xanthomonas_phage	2.0e-70	32.8
WP_002215319.1\|1672904_1673936_-	fimbrial protein	NA	NA	NA	NA
WP_002211584.1\|1673942_1675124_-	ImpA family type VI secretion system protein	NA	NA	NA	NA
WP_002211583.1\|1675222_1676248_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_002211582.1\|1676247_1678128_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_002215317.1\|1678910_1681586_+	type VI secretion system ATPase TssH	A0A223W0B1	Agrobacterium_phage	1.0e-81	32.3
WP_002211580.1\|1681786_1682332_+	type 1 fimbrial protein	NA	NA	NA	NA
WP_002211579.1\|1682488_1683250_+	fimbria/pilus periplasmic chaperone	NA	NA	NA	NA
WP_002215157.1\|1683377_1684928_+	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_002209743.1\|1684949_1686158_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_002211577.1\|1686182_1687373_+	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_002211576.1\|1687357_1687966_+	type 1 fimbrial protein	NA	NA	NA	NA
WP_002211575.1\|1688070_1688595_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_002211574.1\|1688618_1690121_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_002211573.1\|1690446_1690932_+	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_002211572.1\|1691205_1691745_+	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_002211571.1\|1691748_1693098_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA

DBSCAN-SWA_5

2020162 : 2038133

Escherichia_phage(50.0%)

protease,transposase,coat

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000255944.1\|2020162_2021185_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_002215943.1\|2021591_2021981_+	ASCH domain-containing protein	NA	NA	NA	NA
WP_002210859.1\|2022090_2022330_-	YebV family protein	NA	NA	NA	NA
WP_002210858.1\|2022537_2023527_-\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_002210857.1\|2023732_2026180_-	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_002210856.1\|2026350_2027103_-	molecular chaperone	NA	NA	NA	NA
WP_002216611.1\|2027133_2027691_-\|coat	spore coat U domain-containing protein	NA	NA	NA	NA
WP_002216613.1\|2027711_2028242_-\|coat	spore coat U domain-containing protein	NA	NA	NA	NA
WP_002210852.1\|2028247_2028802_-\|coat	spore coat U domain-containing protein	NA	NA	NA	NA
WP_002216616.1\|2029280_2031932_-	PqiB family protein	NA	NA	NA	NA
WP_002367629.1\|2031900_2033148_-	membrane integrity lipid transport subunit YebS	NA	NA	NA	NA
WP_002210850.1\|2033379_2033877_+	GAF domain-containing protein	NA	NA	NA	NA
WP_002210849.1\|2033972_2034686_+	RNA chaperone ProQ	NA	NA	NA	NA
WP_002210848.1\|2034705_2036778_+	carboxy terminal-processing peptidase	A0A0R6PIZ1	Moraxella_phage	4.0e-86	34.8
WP_002210847.1\|2037251_2038133_+\|protease	protease HtpX	NA	NA	NA	NA

DBSCAN-SWA_6

2328663 : 2437794

109

Escherichia_phage(14.04%)

lysis,integrase,transposase,tail

attL 2333663:2333706|attR 2446809:2446852

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002209743.1\|2328663_2329872_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_002210642.1\|2329907_2330666_-	TonB system transport protein TonB	NA	NA	NA	NA
WP_002210643.1\|2330966_2331263_+	YciI family protein	NA	NA	NA	NA
WP_002217646.1\|2331485_2331731_+	hypothetical protein	NA	NA	NA	NA
WP_002210644.1\|2331846_2332110_-	hypothetical protein	NA	NA	NA	NA
WP_002210646.1\|2332330_2332870_-	outer membrane beta-barrel protein	A0A1B0VBR9	Salmonella_phage	2.1e-26	42.4
WP_002388651.1\|2333298_2333475_-	YciY family protein	NA	NA	NA	NA
2333663:2333706	attL	NA	NA	NA	NA
WP_002210648.1\|2333916_2335377_+	cardiolipin synthase	NA	NA	NA	NA
WP_002210649.1\|2335541_2335865_+	YciU family protein	NA	NA	NA	NA
WP_002210650.1\|2336163_2336379_-	hypothetical protein	NA	NA	NA	NA
WP_002210651.1\|2336939_2337941_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.7e-24	34.7
WP_002210652.1\|2337937_2338939_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.2e-14	29.2
WP_025470761.1\|2338950_2339859_-	oligopeptide ABC transporter permease OppC	NA	NA	NA	NA
WP_002210654.1\|2339874_2340795_-	oligopeptide ABC transporter permease OppB	NA	NA	NA	NA
WP_002218177.1\|2340881_2342519_-	oligopeptide ABC transporter substrate-binding protein OppA	NA	NA	NA	NA
WP_002210656.1\|2343356_2344001_-	YchE family NAAT transporter	NA	NA	NA	NA
WP_002210657.1\|2344807_2347483_+	bifunctional acetaldehyde-CoA/alcohol dehydrogenase	NA	NA	NA	NA
WP_000255944.1\|2348022_2349045_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_001297096.1\|2349044_2349824_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_002210659.1\|2350192_2350783_-	thymidine kinase	A0A1Z1LYD5	Serratia_phage	1.5e-54	55.8
WP_002223593.1\|2351532_2351940_+	DNA-binding transcriptional regulator H-NS	NA	NA	NA	NA
WP_002210664.1\|2352374_2353721_-	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	1.9e-81	38.3
WP_002210665.1\|2354027_2355044_-	two-component system response regulator RssB	NA	NA	NA	NA
WP_002213759.1\|2355930_2356389_-\|transposase	IS200/IS605-like element IS1541A family transposase	NA	NA	NA	NA
WP_002210666.1\|2357088_2357553_+	YchJ family protein	NA	NA	NA	NA
WP_002210667.1\|2357636_2358506_+	formyltetrahydrofolate deformylase	M4QRX9	Synechococcus_phage	5.5e-13	37.3
WP_002209743.1\|2358468_2359677_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_002211665.1\|2360548_2361409_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002211667.1\|2362218_2363025_+	exodeoxyribonuclease III	NA	NA	NA	NA
WP_002211668.1\|2363122_2363509_+	pyrimidine (deoxy)nucleoside triphosphate diphosphatase	NA	NA	NA	NA
WP_002211669.1\|2363521_2363812_-	DUF1496 domain-containing protein	NA	NA	NA	NA
WP_002211670.1\|2363808_2365734_-	DNA topoisomerase III	A0A1X9I6W8	Streptococcus_phage	4.2e-37	30.4
WP_002211671.1\|2365795_2366842_-	selenide, water dikinase SelD	NA	NA	NA	NA
WP_002211673.1\|2367066_2367618_-	NAD(P)H nitroreductase	NA	NA	NA	NA
WP_002211674.1\|2367780_2369631_+	signal peptide peptidase SppA	NA	NA	NA	NA
WP_002211675.1\|2369747_2370764_+	asparaginase	NA	NA	NA	NA
WP_002211676.1\|2370778_2371426_+	bifunctional nicotinamidase/pyrazinamidase	A0A2K9L6K4	Tupanvirus	1.8e-21	33.0
WP_002217933.1\|2371559_2371832_-	YeaC family protein	NA	NA	NA	NA
WP_002211677.1\|2371902_2372316_-	peptide-methionine (R)-S-oxide reductase MsrB	NA	NA	NA	NA
WP_002224141.1\|2372663_2373659_+	glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_016579925.1\|2373972_2374848_+	D-hexose-6-phosphate mutarotase	NA	NA	NA	NA
WP_002430110.1\|2374920_2375670_-	MipA/OmpV family protein	NA	NA	NA	NA
WP_002211681.1\|2376113_2378048_+	protein kinase YeaG	NA	NA	NA	NA
WP_002216501.1\|2378197_2379472_+	YeaH/YhbH family protein	A0A140HLI1	Bacillus_phage	1.5e-11	37.1
WP_002211683.1\|2379579_2380698_+	DMT family transporter	NA	NA	NA	NA
WP_002211684.1\|2380732_2381638_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002211685.1\|2381835_2382705_+	pirin family protein	NA	NA	NA	NA
WP_002216508.1\|2382969_2384172_+	multidrug effflux MFS transporter	S4TR35	Salmonella_phage	7.6e-29	29.1
WP_002211686.1\|2384187_2385492_-	D-amino acid dehydrogenase	NA	NA	NA	NA
WP_002211687.1\|2385957_2387493_+	SpoVR family protein	NA	NA	NA	NA
WP_002211688.1\|2387710_2388430_-	fatty acid metabolism transcriptional regulator FadR	NA	NA	NA	NA
WP_002211689.1\|2388673_2390248_+	sodium/proton antiporter NhaB	NA	NA	NA	NA
WP_002227934.1\|2390483_2391014_+	disulfide bond formation protein DsbB	NA	NA	NA	NA
WP_002214494.1\|2391430_2391787_-	hypothetical protein	NA	NA	NA	NA
WP_002211692.1\|2392878_2393619_+	hypothetical protein	NA	NA	NA	NA
WP_002211693.1\|2393635_2394835_+	cysteine desulfurase	A0A1X7QGF3	Faustovirus	2.4e-38	29.6
WP_002214492.1\|2394838_2396011_+	MFS transporter	NA	NA	NA	NA
WP_002209743.1\|2396315_2397524_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_097608205.1\|2397744_2398113_-\|tail	phage tail protein	B6SCW7	Bacteriophage	5.0e-08	42.0
WP_002211696.1\|2398174_2399092_-	hypothetical protein	NA	NA	NA	NA
WP_002211697.1\|2399108_2400107_-	hypothetical protein	NA	NA	NA	NA
WP_002211698.1\|2400106_2403310_-	host specificity protein J	F1C571	Cronobacter_phage	0.0e+00	60.5
WP_002359202.1\|2403485_2403707_+	hypothetical protein	NA	NA	NA	NA
WP_002211700.1\|2403881_2404502_-\|tail	tail assembly protein	K7PGY0	Enterobacteria_phage	3.2e-55	57.0
WP_002211701.1\|2404557_2404773_-	hypothetical protein	NA	NA	NA	NA
WP_002214482.1\|2404915_2405467_-	zinc ribbon domain-containing protein	S4TR42	Salmonella_phage	9.5e-27	58.0
WP_002211704.1\|2405565_2406573_-	hypothetical protein	A0A2H4J0P1	uncultured_Caudovirales_phage	4.1e-36	33.0
WP_002211705.1\|2406646_2406814_-	hypothetical protein	G9L6D7	Escherichia_phage	5.2e-13	61.8
WP_002211706.1\|2406937_2407369_+	Arc family DNA-binding protein	G9L6D6	Escherichia_phage	2.5e-30	58.4
WP_002211707.1\|2407447_2408080_-	hypothetical protein	NA	NA	NA	NA
WP_002211708.1\|2408340_2409051_-	peptidase P60	K7P6F5	Enterobacteria_phage	1.3e-108	76.8
WP_002211709.1\|2409053_2409806_-\|tail	phage minor tail protein L	A0A1W6JNX9	Morganella_phage	9.4e-102	67.7
WP_002213759.1\|2409926_2410385_-\|transposase	IS200/IS605-like element IS1541A family transposase	NA	NA	NA	NA
WP_002211710.1\|2410690_2411032_-\|tail	phage tail protein	Q6UAW6	Klebsiella_phage	1.7e-21	50.0
WP_002211711.1\|2411034_2414538_-\|tail	phage tail tape measure protein	K7PMB9	Enterobacterial_phage	5.2e-118	33.2
WP_071525538.1\|2414538_2414799_-	hypothetical protein	A0A0S2SY90	Pseudomonas_phage	3.7e-13	50.0
WP_002211712.1\|2414846_2415158_-	hypothetical protein	I6PDG2	Cronobacter_phage	1.4e-30	58.3
WP_002211713.1\|2415170_2416091_-\|tail	phage tail protein	I6PBN6	Cronobacter_phage	4.4e-61	49.1
WP_002211714.1\|2416156_2416564_-	DUF4128 domain-containing protein	NA	NA	NA	NA
WP_002211715.1\|2416560_2417145_-	hypothetical protein	G8C7Q1	Escherichia_phage	3.6e-48	52.1
WP_002211716.1\|2417146_2417497_-	hypothetical protein	I6PD77	Cronobacter_phage	6.9e-31	56.0
WP_002211717.1\|2417498_2417753_-	hypothetical protein	J9Q7U0	Salmonella_phage	2.2e-18	53.1
WP_002211718.1\|2417749_2418232_-	hypothetical protein	G8C7P9	Escherichia_phage	6.4e-27	46.1
WP_002211719.1\|2418279_2419485_-	hypothetical protein	A0A1B0VMF8	Pseudomonas_phage	1.8e-142	79.2
WP_002211720.1\|2419498_2420272_-	hypothetical protein	A0A1B0VMG1	Pseudomonas_phage	2.8e-69	62.3
WP_002211721.1\|2420393_2421506_-	hypothetical protein	I6PD76	Cronobacter_phage	6.0e-121	58.2
WP_002228446.1\|2421506_2422148_-	DUF4055 domain-containing protein	A0A1B0VMH0	Pseudomonas_phage	3.8e-59	54.1
WP_002228445.1\|2422166_2422895_-	hypothetical protein	A0A1B0VMH0	Pseudomonas_phage	4.6e-61	51.4
WP_002211722.1\|2422894_2423869_-	hypothetical protein	A0A1W6JNY3	Morganella_phage	2.3e-153	81.1
WP_002209743.1\|2423873_2425082_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_002211723.1\|2425129_2425714_-	hypothetical protein	A0A0R6PHH0	Moraxella_phage	4.8e-69	70.7
WP_002211724.1\|2425717_2426167_-	DUF2280 domain-containing protein	I6S1P9	Salmonella_phage	1.0e-47	72.9
WP_002211725.1\|2426197_2426833_-	hypothetical protein	I6S676	Salmonella_phage	7.2e-87	71.4
WP_002211727.1\|2427289_2428003_-	hypothetical protein	Q5MBW0	Stx1-converting_phage	7.6e-69	60.2
WP_002211729.1\|2428548_2429007_-\|lysis	lysis protein	A0A2H4JHL8	uncultured_Caudovirales_phage	4.9e-21	45.3
WP_002211730.1\|2428991_2429504_-	lysozyme	I6PBN2	Cronobacter_phage	9.7e-50	61.6
WP_002430108.1\|2429534_2429732_-	hypothetical protein	B6SD15	Bacteriophage	4.9e-18	64.4
WP_002215644.1\|2429977_2430253_+	hypothetical protein	NA	NA	NA	NA
WP_002211731.1\|2430249_2430459_-	hypothetical protein	NA	NA	NA	NA
WP_002211732.1\|2430882_2431446_-	hypothetical protein	B6SD63	Bacteriophage	9.4e-30	58.0
WP_002215638.1\|2431494_2431713_-	hypothetical protein	NA	NA	NA	NA
WP_002215636.1\|2431716_2432106_-	antitermination protein	A0A1W6JNX1	Morganella_phage	1.4e-45	68.8
WP_002211735.1\|2432106_2432712_-	recombination protein NinG	A0A1P8DTE0	Proteus_phage	2.8e-56	56.9
WP_002211736.1\|2432785_2433232_-	recombination protein NinB	A0A2H4J8D9	uncultured_Caudovirales_phage	3.9e-47	62.5
WP_071525537.1\|2433207_2433957_+	DNA adenine methylase	Q5QF26	Pseudomonas_virus	1.5e-54	48.5
WP_002215632.1\|2434256_2434517_+	excisionase family protein	Q859D3	Escherichia_coli_phage	1.7e-10	42.9
WP_001297096.1\|2434684_2435464_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_000255944.1\|2435463_2436486_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_002211738.1\|2436555_2437794_+\|integrase	site-specific integrase	Q20GI2	Phage_258-320	2.3e-121	53.3
2446809:2446852	attR	NA	NA	NA	NA

DBSCAN-SWA_7

2899984 : 2944502

Indivirus(14.29%)

lysis,plate,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002211870.1\|2899984_2902012_+\|tRNA	methionine--tRNA ligase	A0A1V0SDF2	Indivirus	8.0e-55	27.1
WP_002213775.1\|2902175_2902634_-\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002228565.1\|2902851_2903514_-	hypothetical protein	NA	NA	NA	NA
WP_002211975.1\|2904211_2905288_+	sugar ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002211974.1\|2905305_2906559_+	hypothetical protein	NA	NA	NA	NA
WP_002211973.1\|2906891_2908073_+	MFS transporter	NA	NA	NA	NA
WP_002211971.1\|2908314_2908722_+	CidA/LrgA family protein	NA	NA	NA	NA
WP_002211970.1\|2908718_2909414_+\|lysis	CidB/LrgB family autolysis modulator	NA	NA	NA	NA
WP_016580979.1\|2909739_2910624_+	cytidine deaminase	NA	NA	NA	NA
WP_002211968.1\|2910979_2912677_+	NAD-dependent malic enzyme	NA	NA	NA	NA
WP_002211966.1\|2912957_2913695_+	outer membrane permeability protein SanA	NA	NA	NA	NA
WP_002211965.1\|2914139_2915150_-	galactose/methyl galactoside ABC transporter permease MglC	NA	NA	NA	NA
WP_002211964.1\|2915170_2916691_-	galactose/methyl galactoside ABC transporter ATP-binding protein MglA	F2Y2R6	Organic_Lake_phycodnavirus	2.6e-10	29.9
WP_002211963.1\|2916920_2917913_-	galactose/glucose ABC transporter substrate-binding protein MglB	NA	NA	NA	NA
WP_002211961.1\|2918660_2919827_-	DUF418 family protein	NA	NA	NA	NA
WP_002211960.1\|2919881_2920544_-	GTP cyclohydrolase I FolE	R9TJA5	Vibrio_phage	5.8e-55	53.5
WP_002211959.1\|2920727_2921879_-	YbfB/YjiJ family MFS transporter	NA	NA	NA	NA
WP_002211958.1\|2922014_2922884_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002211957.1\|2923157_2924297_+	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase	E3SJ82	Synechococcus_phage	5.2e-35	29.9
WP_002211956.1\|2924317_2925160_+	S-formylglutathione hydrolase	NA	NA	NA	NA
WP_002227980.1\|2925416_2925629_+	peptide antibiotic darobactin C	NA	NA	NA	NA
WP_002215886.1\|2925712_2928073_+	darobactin export ABC transporter permease subunit	NA	NA	NA	NA
WP_002211952.1\|2928074_2929337_+	darobactin export ABC transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_002211951.1\|2929338_2930007_+	darobactin export ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.4e-35	40.0
WP_016581226.1\|2930016_2931327_+	darobactin maturation radical SAM/SPASM protein DarE	NA	NA	NA	NA
WP_002211949.1\|2931861_2933136_+	molybdopterin molybdotransferase MoeA	NA	NA	NA	NA
WP_002211948.1\|2933137_2933908_+	molybdopterin-synthase adenylyltransferase MoeB	NA	NA	NA	NA
WP_002209743.1\|2934043_2935252_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_002211947.1\|2935295_2935949_-	hypothetical protein	NA	NA	NA	NA
WP_002227996.1\|2936176_2937772_-	ABC-F family ATPase	A0A2K9L0W2	Tupanvirus	6.1e-58	28.5
WP_002211945.1\|2938454_2939078_+	hypothetical protein	NA	NA	NA	NA
WP_002211944.1\|2939289_2940657_-	membrane protein	NA	NA	NA	NA
WP_002211943.1\|2940681_2941134_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_002214552.1\|2941133_2941715_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_002211941.1\|2941689_2942775_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_002211940.1\|2942738_2944502_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA

DBSCAN-SWA_8

2969367 : 3036460

Streptococcus_phage(20.0%)

protease,plate,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002213011.1\|2969367_2970720_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_002214707.1\|2970731_2972282_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_002213014.1\|2972324_2972825_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_002213016.1\|2973813_2974662_-	ACP S-malonyltransferase	NA	NA	NA	NA
WP_002213017.1\|2974760_2975009_-	acyl carrier protein	NA	NA	NA	NA
WP_002228570.1\|2975046_2975487_-	lipocalin-like domain-containing protein	NA	NA	NA	NA
WP_002213024.1\|2975573_2976362_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_002213025.1\|2976364_2977117_-	enoyl-CoA hydratase	NA	NA	NA	NA
WP_002213026.1\|2977118_2977838_-	enoyl-CoA hydratase/isomerase family protein	NA	NA	NA	NA
WP_002213028.1\|2977830_2979069_-	hydroxymethylglutaryl-CoA synthase family protein	NA	NA	NA	NA
WP_002213030.1\|2979084_2979822_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_002213032.1\|2979823_2981107_-	beta-ketoacyl-[acyl-carrier-protein] synthase family protein	NA	NA	NA	NA
WP_002213034.1\|2981096_2981621_-	beta-hydroxyacyl-ACP dehydratase	NA	NA	NA	NA
WP_002213036.1\|2981884_2982103_-	hypothetical protein	NA	NA	NA	NA
WP_002213038.1\|2982833_2983580_+	SDR family oxidoreductase	F2NZ40	Diadromus_pulchellus_ascovirus	3.3e-14	31.4
WP_002213039.1\|2983733_2986151_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_002213046.1\|2989796_2990126_+	sulfurtransferase TusE	NA	NA	NA	NA
WP_002213049.1\|2990177_2990456_-	acylphosphatase	NA	NA	NA	NA
WP_002213052.1\|2990549_2991740_+	23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI	W6LLI2	Streptococcus_phage	2.1e-26	28.1
WP_002213054.1\|2991800_2992118_+	heat shock protein HspQ	NA	NA	NA	NA
WP_002213056.1\|2992226_2992643_-	CoA-binding protein	NA	NA	NA	NA
WP_002213058.1\|2992958_2993639_+	DUF2057 family protein	NA	NA	NA	NA
WP_002213060.1\|2993817_2994282_+	methylglyoxal synthase	NA	NA	NA	NA
WP_002221095.1\|2994342_2996397_-	DNA helicase IV	A7KV33	Bacillus_phage	1.5e-16	25.8
WP_002213062.1\|2996590_2997037_+	YccF domain-containing protein	NA	NA	NA	NA
WP_002213063.1\|2997066_2999205_+	TIGR01666 family membrane protein	NA	NA	NA	NA
WP_002213064.1\|2999306_2999942_-	TfoX/Sxy family DNA transformation protein	NA	NA	NA	NA
WP_002213065.1\|3000170_3000677_+	cell division inhibitor SulA	NA	NA	NA	NA
WP_002213066.1\|3001034_3002096_+	porin OmpA	NA	NA	NA	NA
WP_002213775.1\|3002285_3002744_+\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002226586.1\|3002912_3003368_-	macrodomain Ter protein MatP	NA	NA	NA	NA
WP_002224683.1\|3003578_3005330_+\|protease	Lon protease family protein	NA	NA	NA	NA
WP_002220006.1\|3005398_3005917_+	bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase	NA	NA	NA	NA
WP_002211286.1\|3006182_3006371_-	hypothetical protein	NA	NA	NA	NA
WP_000255944.1\|3007004_3008027_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_001297096.1\|3008026_3008806_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_002213775.1\|3009966_3010425_-\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002228015.1\|3010622_3010790_-	ribosome modulation factor	NA	NA	NA	NA
WP_002211289.1\|3011059_3011638_-	membrane integrity-associated transporter subunit PqiC	NA	NA	NA	NA
WP_002211290.1\|3012011_3013664_-	intermembrane transport protein PqiB	NA	NA	NA	NA
WP_002211291.1\|3013650_3014937_-	membrane integrity-associated transporter subunit PqiA	NA	NA	NA	NA
WP_002211292.1\|3015065_3016979_-	ABC transporter ATP-binding protein	A0A2K9L3Z8	Tupanvirus	1.5e-47	28.9
WP_002211293.1\|3016984_3019105_-	bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL	NA	NA	NA	NA
WP_002363919.1\|3019207_3020317_+	MOSC domain-containing protein	NA	NA	NA	NA
WP_002211295.1\|3020342_3020894_-	cell division protein ZapC	NA	NA	NA	NA
WP_002211296.1\|3021076_3022087_-	quinone-dependent dihydroorotate dehydrogenase	NA	NA	NA	NA
WP_002220013.1\|3022695_3025311_-	aminopeptidase N	NA	NA	NA	NA
WP_002228013.1\|3026026_3027232_+	nicotinate phosphoribosyltransferase	NA	NA	NA	NA
WP_002211301.1\|3027730_3029131_+\|tRNA	asparagine--tRNA ligase	A0A167RLM0	Powai_lake_megavirus	6.5e-80	35.2
WP_002354007.1\|3029431_3030511_+	porin OmpF	Q1MVN1	Enterobacteria_phage	3.2e-111	56.5
WP_002211303.1\|3030767_3031958_+	aspartate/tyrosine/aromatic aminotransferase	NA	NA	NA	NA
WP_002430096.1\|3032111_3032228_+	hypothetical protein	NA	NA	NA	NA
WP_002211304.1\|3032381_3033029_-	MBL fold metallo-hydrolase	A0A1X9I5D3	Streptococcus_phage	2.2e-22	32.3
WP_002211305.1\|3033089_3033638_-	YcbK family protein	A0A0K1LLY2	Rhodobacter_phage	7.8e-05	34.7
WP_002217987.1\|3033861_3035718_-	L,D-transpeptidase	NA	NA	NA	NA
WP_002213775.1\|3036001_3036460_-\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA

DBSCAN-SWA_9

3207009 : 3225374

Vibrio_phage(25.0%)

plate,transposase,coat,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002213775.1\|3207009_3207468_-\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002208835.1\|3207668_3208673_-	nucleoid-associated protein YejK	A0A1V0E8C0	Vibrio_phage	3.1e-84	47.7
WP_002208836.1\|3208850_3209078_+	YejL family protein	NA	NA	NA	NA
WP_002208837.1\|3209105_3210902_+	DUF3413 domain-containing protein	NA	NA	NA	NA
WP_002230704.1\|3211132_3211516_+	DUF927 domain-containing protein	A0A1W6JPG0	Morganella_phage	7.8e-36	66.7
WP_002208839.1\|3211872_3213021_+	HNH endonuclease	NA	NA	NA	NA
WP_002208840.1\|3213033_3213522_+	hypothetical protein	NA	NA	NA	NA
WP_002208841.1\|3214221_3214584_+	hypothetical protein	NA	NA	NA	NA
WP_002208842.1\|3214709_3216146_-	6-phospho-beta-glucosidase	NA	NA	NA	NA
WP_002208843.1\|3216436_3217177_-	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
WP_002208845.1\|3217474_3218254_-\|tail	tail fiber protein	Q9MCR6	Enterobacteria_phage	7.1e-52	52.4
WP_002208846.1\|3218350_3218698_-	DUF2313 domain-containing protein	A0A2P9JZK7	Alteromonadaceae_phage	6.4e-21	41.3
WP_002215458.1\|3218694_3218955_-	DUF2313 domain-containing protein	NA	NA	NA	NA
WP_002208847.1\|3218951_3220088_-\|plate	baseplate J/gp47 family protein	B5TK75	Pseudomonas_phage	4.5e-31	30.5
WP_002208848.1\|3220091_3220547_-	hypothetical protein	A0A0C4UR04	Shigella_phage	4.3e-17	43.8
WP_002215460.1\|3220543_3221140_-\|plate	baseplate assembly protein	NA	NA	NA	NA
WP_002208850.1\|3221155_3222211_-\|tail	tail protein	M1PVV2	Vibrio_phage	1.3e-37	27.2
WP_002208852.1\|3222207_3223614_-	hypothetical protein	Q8SBG8	Shigella_phage	2.1e-17	33.7
WP_002208853.1\|3223880_3225374_-\|coat	coat protein	NA	NA	NA	NA

DBSCAN-SWA_10

3303500 : 3339716

uncultured_virus(12.5%)

transposase,holin,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002228612.1\|3303500_3304439_-\|tRNA	tRNA dihydrouridine(16) synthase DusC	NA	NA	NA	NA
WP_002210776.1\|3304738_3305668_-	DUF4097 domain-containing protein	NA	NA	NA	NA
WP_002213759.1\|3306082_3306541_-\|transposase	IS200/IS605-like element IS1541A family transposase	NA	NA	NA	NA
WP_002209743.1\|3308352_3309561_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_002223532.1\|3309735_3310050_-	hypothetical protein	NA	NA	NA	NA
WP_002228617.1\|3310133_3310370_-	hypothetical protein	NA	NA	NA	NA
WP_016256670.1\|3310510_3310837_-	hypothetical protein	NA	NA	NA	NA
WP_002228620.1\|3310870_3311065_-	hypothetical protein	NA	NA	NA	NA
WP_002220152.1\|3312278_3313634_-	ATP-dependent RNA helicase RhlE	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	4.1e-55	35.6
WP_002220154.1\|3314024_3314735_+	transcriptional regulator CecR	NA	NA	NA	NA
WP_002220156.1\|3314786_3315773_+	secretion protein HlyD	NA	NA	NA	NA
WP_002220158.1\|3315786_3317529_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	6.3e-24	34.6
WP_002220159.1\|3317533_3318709_+	ABC transporter permease	NA	NA	NA	NA
WP_002220162.1\|3318721_3319828_+	ABC transporter permease	NA	NA	NA	NA
WP_002220163.1\|3319866_3320193_-	EthD family reductase	NA	NA	NA	NA
WP_002220165.1\|3320203_3320431_-	N5,N10-methylene tetrahydromethanopterin reductase	NA	NA	NA	NA
WP_002220168.1\|3320985_3321897_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002220169.1\|3321897_3323007_-	alkene reductase	NA	NA	NA	NA
WP_002220170.1\|3323354_3324719_-	sigma 54-interacting transcriptional regulator	Q6XM27	Feldmannia_irregularis_virus	1.3e-05	29.1
WP_002220171.1\|3324705_3326520_-	PAS domain-containing sensor histidine kinase	W8CYF6	Bacillus_phage	1.0e-16	28.4
WP_002220173.1\|3326877_3327351_+	zinc resistance sensor/chaperone ZraP	NA	NA	NA	NA
WP_002213759.1\|3328156_3328615_-\|transposase	IS200/IS605-like element IS1541A family transposase	NA	NA	NA	NA
WP_002214195.1\|3329543_3330407_-	xanthosine phosphorylase	Q5YBA4	Grouper_iridovirus	2.3e-51	40.7
WP_002214197.1\|3330752_3331601_+	DMT family transporter	NA	NA	NA	NA
WP_002214199.1\|3331638_3332532_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002228035.1\|3332763_3334812_-\|holin	choline transporter	A0A2I7QNT1	Vibrio_phage	1.4e-19	28.5
WP_002218278.1\|3335176_3335773_+	transcriptional regulator BetI	NA	NA	NA	NA
WP_016581311.1\|3335830_3337303_+	betaine-aldehyde dehydrogenase	NA	NA	NA	NA
WP_002220180.1\|3337325_3339029_+\|holin	choline dehydrogenase	A0A1V0S9M4	Catovirus	9.4e-57	31.5
WP_002213775.1\|3339257_3339716_-\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA

DBSCAN-SWA_11

3409430 : 3415602

Escherichia_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002210709.1\|3409430_3409631_+	AlpA family transcriptional regulator	A0A1V0E8E5	Vibrio_phage	1.6e-08	51.7
WP_002215949.1\|3409630_3410173_+	ash family protein	NA	NA	NA	NA
WP_002215950.1\|3410165_3411125_+	toprim domain-containing protein	A0A1W6JPG0	Morganella_phage	1.6e-50	41.0
WP_002210707.1\|3411121_3412210_+	AAA family ATPase	A0A2H4JFA4	uncultured_Caudovirales_phage	1.4e-114	60.4
WP_002210705.1\|3412558_3412873_-	putative addiction module antidote protein	NA	NA	NA	NA
WP_002215951.1\|3412878_3413196_-	type II toxin-antitoxin system RelE/ParE family toxin	A0A141GEX6	Brucella_phage	2.0e-13	48.1
WP_000255944.1\|3413800_3414823_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_001297096.1\|3414822_3415602_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6

DBSCAN-SWA_12

3656871 : 3732226

Staphylococcus_phage(25.0%)

protease,plate,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002213759.1\|3656871_3657330_-\|transposase	IS200/IS605-like element IS1541A family transposase	NA	NA	NA	NA
WP_002209965.1\|3657637_3659632_-	transketolase	NA	NA	NA	NA
WP_002209967.1\|3660122_3660875_+	M48 family metallopeptidase	NA	NA	NA	NA
WP_071525520.1\|3661020_3661131_+	gluconate 5-dehydrogenase	NA	NA	NA	NA
WP_002209968.1\|3661164_3661485_-	non-heme iron oxygenase ferredoxin subunit	NA	NA	NA	NA
WP_002213775.1\|3661695_3662154_-\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002209969.1\|3662354_3664334_-	biosynthetic arginine decarboxylase	NA	NA	NA	NA
WP_002209971.1\|3665540_3666695_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.7e-126	62.1
WP_002228653.1\|3666887_3667400_+\|protease	SprT family zinc-dependent metalloprotease	NA	NA	NA	NA
WP_002209973.1\|3667497_3668205_+	deoxyribonuclease I	NA	NA	NA	NA
WP_002209975.1\|3668456_3669188_+	16S rRNA (uracil(1498)-N(3))-methyltransferase	NA	NA	NA	NA
WP_002209976.1\|3669213_3670173_+	glutathione synthase	NA	NA	NA	NA
WP_002209977.1\|3670288_3670852_+	YqgE/AlgH family protein	NA	NA	NA	NA
WP_002209978.1\|3670851_3671274_+	Holliday junction resolvase RuvX	NA	NA	NA	NA
WP_002209979.1\|3671453_3672338_+	N-carbamoylputrescine amidase	A7IVZ1	Paramecium_bursaria_Chlorella_virus	3.1e-80	51.0
WP_002209980.1\|3672341_3673457_+	agmatine deiminase	M1I1E2	Acanthocystis_turfacea_Chlorella_virus	3.0e-96	50.7
WP_002209981.1\|3673565_3674690_-	type IV pilus twitching motility protein PilT	NA	NA	NA	NA
WP_002215609.1\|3674709_3675408_+	YggS family pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_002209983.1\|3675540_3676362_+	pyrroline-5-carboxylate reductase	NA	NA	NA	NA
WP_002209984.1\|3676649_3677204_+	YggT family protein	NA	NA	NA	NA
WP_002215612.1\|3677200_3677491_+	YggU family protein	NA	NA	NA	NA
WP_002215614.1\|3677590_3678184_+	XTP/dITP diphosphatase	NA	NA	NA	NA
WP_002209987.1\|3678176_3679307_+	radical SAM family heme chaperone HemW	NA	NA	NA	NA
WP_002224905.1\|3679496_3688829_-	phage minor structural protein	NA	NA	NA	NA
WP_002209989.1\|3690168_3691095_-	glutaminase B	NA	NA	NA	NA
WP_002209990.1\|3691205_3691532_-	YggL family protein	NA	NA	NA	NA
WP_002209991.1\|3691531_3692251_-\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_002228057.1\|3692588_3693704_+	A/G-specific adenine glycosylase	NA	NA	NA	NA
WP_002209994.1\|3693881_3694154_+	oxidative damage protection protein	NA	NA	NA	NA
WP_002209995.1\|3694336_3695413_+	membrane-bound lytic murein transglycosylase MltC	NA	NA	NA	NA
WP_002209997.1\|3695712_3696813_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002209998.1\|3696916_3698950_+	TonB-dependent siderophore receptor	A0A0P0I887	Acinetobacter_phage	4.5e-05	26.1
WP_002209999.1\|3699032_3700016_-	ABC transporter permease	NA	NA	NA	NA
WP_002210000.1\|3700048_3701548_-	sugar ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	5.2e-19	31.7
WP_002210001.1\|3701593_3702553_-	substrate-binding domain-containing protein	NA	NA	NA	NA
WP_002210002.1\|3703108_3705271_-	ornithine decarboxylase SpeF	NA	NA	NA	NA
WP_002210005.1\|3706599_3707235_-	DUF2345 domain-containing protein	NA	NA	NA	NA
WP_086016632.1\|3707842_3708540_-\|transposase	IS1 family transposase	A0A0U2RK18	Escherichia_phage	1.3e-60	48.5
WP_002210008.1\|3708635_3709403_-	hypothetical protein	NA	NA	NA	NA
WP_002210009.1\|3709389_3711687_-	M23 family metallopeptidase	NA	NA	NA	NA
WP_002210010.1\|3711702_3712338_-	DUF2345 domain-containing protein	NA	NA	NA	NA
WP_002216110.1\|3713562_3713757_-	hypothetical protein	NA	NA	NA	NA
WP_016257642.1\|3713940_3714297_-	hypothetical protein	NA	NA	NA	NA
WP_002210011.1\|3714440_3716663_-	hydroxyethylthiazole kinase	NA	NA	NA	NA
WP_002210012.1\|3716677_3719026_-	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	3.1e-18	33.3
WP_002210013.1\|3719022_3721671_-	type VI secretion system ATPase TssH	K4FB40	Cronobacter_phage	4.8e-92	29.5
WP_002210014.1\|3722088_3722580_-	Hcp family type VI secretion system effector	NA	NA	NA	NA
WP_002228049.1\|3722583_3724320_-	OmpA family protein	NA	NA	NA	NA
WP_002210015.1\|3724319_3725006_-	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_002211664.1\|3725002_3726355_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_002215896.1\|3726366_3727911_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_002211662.1\|3727953_3728454_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_002215900.1\|3730729_3731125_-	lipoprotein	NA	NA	NA	NA
WP_002215902.1\|3731575_3732226_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_13

4007873 : 4083745

Escherichia_phage(20.0%)

plate,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000255944.1\|4007873_4008896_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_001297096.1\|4008895_4009675_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_002210424.1\|4009936_4010323_-	8-oxo-dGTP diphosphatase MutT	A0A0B5CYJ3	Rhizoctonia_fumigata_mycovirus	8.4e-06	30.4
WP_002210426.1\|4010617_4013332_-	preprotein translocase subunit SecA	NA	NA	NA	NA
WP_002210427.1\|4013409_4013943_-	secA regulator SecM	NA	NA	NA	NA
WP_002210428.1\|4013971_4014496_+	DUF721 domain-containing protein	NA	NA	NA	NA
WP_002228285.1\|4014662_4015583_-	UDP-3-O-acyl-N-acetylglucosamine deacetylase	NA	NA	NA	NA
WP_002210430.1\|4015682_4016834_-	cell division protein FtsZ	NA	NA	NA	NA
WP_002210431.1\|4016906_4018163_-	cell division protein FtsA	NA	NA	NA	NA
WP_002228100.1\|4018189_4019017_-	cell division protein FtsQ	NA	NA	NA	NA
WP_002210432.1\|4019018_4019939_-	D-alanine--D-alanine ligase	NA	NA	NA	NA
WP_002216457.1\|4019931_4021407_-	UDP-N-acetylmuramate--L-alanine ligase	NA	NA	NA	NA
WP_002210434.1\|4021544_4022615_-	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase	NA	NA	NA	NA
WP_002210435.1\|4022611_4023814_-	cell division protein FtsW	NA	NA	NA	NA
WP_002210436.1\|4023813_4025130_-	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	NA	NA	NA	NA
WP_002210437.1\|4025132_4026215_-	phospho-N-acetylmuramoyl-pentapeptide- transferase	NA	NA	NA	NA
WP_002210438.1\|4026208_4027585_-	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase	NA	NA	NA	NA
WP_002210439.1\|4027581_4029069_-	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase	NA	NA	NA	NA
WP_002210440.1\|4029055_4030819_-	peptidoglycan glycosyltransferase FtsI	NA	NA	NA	NA
WP_002210441.1\|4030884_4031202_-	cell division protein FtsL	NA	NA	NA	NA
WP_002210442.1\|4031198_4032161_-	16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH	NA	NA	NA	NA
WP_002210443.1\|4032163_4032622_-	division/cell wall cluster transcriptional repressor MraZ	NA	NA	NA	NA
WP_087768171.1\|4033176_4033266_-	gluconate 5-dehydrogenase	NA	NA	NA	NA
WP_002210446.1\|4033723_4034164_+	L-alanine exporter AlaE	NA	NA	NA	NA
WP_002210447.1\|4034294_4035305_-	catabolite repressor/activator	NA	NA	NA	NA
WP_002213775.1\|4035809_4036268_-\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002424260.1\|4036466_4036991_-	acetolactate synthase small subunit	NA	NA	NA	NA
WP_002228103.1\|4036963_4038691_-	acetolactate synthase 3 large subunit	A0A0P0YLY7	Yellowstone_lake_phycodnavirus	7.8e-59	29.4
WP_002216437.1\|4039150_4040956_-	long-chain fatty acid--CoA ligase	A0A1V0SBX8	Catovirus	3.5e-38	23.2
WP_002216434.1\|4041509_4042466_-	transcriptional regulator LeuO	NA	NA	NA	NA
WP_002210452.1\|4043143_4043359_+	hypothetical protein	NA	NA	NA	NA
WP_050882072.1\|4043787_4044246_+\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002210453.1\|4044392_4045955_+	2-isopropylmalate synthase	NA	NA	NA	NA
WP_002210454.1\|4045957_4047049_+	3-isopropylmalate dehydrogenase	NA	NA	NA	NA
WP_002210455.1\|4047050_4048481_+	3-isopropylmalate dehydratase large subunit	NA	NA	NA	NA
WP_002210456.1\|4048495_4049098_+	3-isopropylmalate dehydratase small subunit	NA	NA	NA	NA
WP_002224086.1\|4049338_4050520_-	MFS transporter	NA	NA	NA	NA
WP_002210461.1\|4051183_4052845_+	HTH-type transcriptional regulator SgrR	NA	NA	NA	NA
WP_002214274.1\|4053784_4054777_+	thiamine ABC transporter substrate binding subunit	NA	NA	NA	NA
WP_002214276.1\|4054752_4056360_+	thiamine/thiamine pyrophosphate ABC transporter permease ThiP	NA	NA	NA	NA
WP_002210464.1\|4056346_4057057_+	thiamine ABC transporter ATP-binding protein ThiQ	G3M9Y6	Bacillus_virus	1.0e-20	34.1
WP_002210465.1\|4057125_4057893_-	DedA family protein	NA	NA	NA	NA
WP_002210466.1\|4058088_4060458_+	DNA polymerase II	A0A0P0YM26	Yellowstone_lake_phycodnavirus	1.5e-31	25.5
WP_002220588.1\|4060918_4063825_+	RNA polymerase-associated protein RapA	A0A1B1IUI1	uncultured_Mediterranean_phage	3.0e-23	37.6
WP_002210468.1\|4064080_4064434_-	hypothetical protein	NA	NA	NA	NA
WP_002210469.1\|4067958_4069569_-	OmpA family protein	NA	NA	NA	NA
WP_002210470.1\|4069565_4070921_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_002210471.1\|4071040_4071532_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_002214737.1\|4071524_4071890_-	DUF4150 domain-containing protein	NA	NA	NA	NA
WP_002210473.1\|4071895_4072513_-	DUF3540 domain-containing protein	NA	NA	NA	NA
WP_002214739.1\|4072505_4073609_-	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_002224087.1\|4073634_4075854_-	DUF2169 domain-containing protein	NA	NA	NA	NA
WP_002210474.1\|4075866_4078215_-	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	2.1e-14	32.9
WP_002210475.1\|4078318_4080907_-	type VI secretion system ATPase TssH	A0A248SJW6	Salicola_phage	1.9e-77	28.7
WP_002210476.1\|4080924_4081908_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_002210477.1\|4081900_4083745_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA

DBSCAN-SWA_14

4209208 : 4273489

Escherichia_phage(28.57%)

plate,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_071525507.1\|4209208_4209547_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_002209171.1\|4209890_4211264_-	hypothetical protein	NA	NA	NA	NA
WP_002209170.1\|4211235_4211958_-	histidine kinase	NA	NA	NA	NA
WP_002209169.1\|4212007_4213333_-	site-specific DNA-methyltransferase	NA	NA	NA	NA
WP_002209167.1\|4214356_4215673_-	McrC family protein	NA	NA	NA	NA
WP_002209166.1\|4215669_4217733_-	McrB family protein	K4I1H4	Acidithiobacillus_phage	5.3e-30	33.2
WP_000255944.1\|4217866_4218889_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_001297096.1\|4218888_4219668_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_086016626.1\|4220332_4221432_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	2.2e-46	39.2
WP_002218887.1\|4227102_4227288_+	hypothetical protein	NA	NA	NA	NA
WP_002210692.1\|4227755_4229345_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	2.2e-68	49.4
WP_002210691.1\|4229404_4230691_+	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_002355296.1\|4230838_4231492_-	DUF1481 domain-containing protein	NA	NA	NA	NA
WP_002210689.1\|4231541_4231817_-	DNA-binding protein HU-alpha	A7KV42	Bacillus_phage	3.6e-19	55.6
WP_002210688.1\|4232005_4232596_-	YjaG family protein	NA	NA	NA	NA
WP_002210687.1\|4232641_4233382_-	deoxyribonuclease V	NA	NA	NA	NA
WP_002210686.1\|4233411_4234479_-	uroporphyrinogen decarboxylase	NA	NA	NA	NA
WP_002210685.1\|4234597_4235383_-	hypothetical protein	NA	NA	NA	NA
WP_002210684.1\|4235475_4236258_-	NAD(+) diphosphatase	NA	NA	NA	NA
WP_002210683.1\|4236354_4236864_+	sigma D regulator	NA	NA	NA	NA
WP_002210682.1\|4237239_4239285_+	phosphomethylpyrimidine synthase ThiC	NA	NA	NA	NA
WP_002210681.1\|4239271_4239946_+	thiamine phosphate synthase	NA	NA	NA	NA
WP_002210680.1\|4239935_4240733_+	HesA/MoeB/ThiF family protein	A0A1V0SAV8	Catovirus	1.6e-11	27.8
WP_002217275.1\|4240729_4240945_+	sulfur carrier protein ThiS	NA	NA	NA	NA
WP_002228257.1\|4240946_4241762_+	thiazole synthase	NA	NA	NA	NA
WP_002210678.1\|4241754_4242885_+	2-iminoacetate synthase ThiH	NA	NA	NA	NA
WP_002213775.1\|4243316_4243775_+\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002210677.1\|4243901_4248122_-	DNA-directed RNA polymerase subunit beta'	A0A2I7QNZ7	Vibrio_phage	8.5e-67	27.0
WP_002210676.1\|4248250_4252279_-	DNA-directed RNA polymerase subunit beta	A0A0N9R0J7	Chrysochromulina_ericina_virus	1.2e-22	29.0
WP_002210675.1\|4252621_4252990_-	50S ribosomal protein L7/L12	NA	NA	NA	NA
WP_002210674.1\|4253056_4253554_-	50S ribosomal protein L10	NA	NA	NA	NA
WP_002210673.1\|4253918_4254623_-	50S ribosomal protein L1	NA	NA	NA	NA
WP_002210672.1\|4254626_4255055_-	50S ribosomal protein L11	NA	NA	NA	NA
WP_002210671.1\|4255245_4255791_-	transcription termination/antitermination protein NusG	A0A291AUS6	Sinorhizobium_phage	5.9e-13	28.3
WP_002210670.1\|4255792_4256176_-	preprotein translocase subunit SecE	NA	NA	NA	NA
WP_002210669.1\|4256426_4257611_-	elongation factor Tu	A0A2K9L516	Tupanvirus	2.0e-13	26.9
WP_001297096.1\|4258667_4259447_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_000255944.1\|4259446_4260469_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_002217850.1\|4260558_4261110_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_002212290.1\|4261320_4262271_+	type I pantothenate kinase	A0A1B1ISL9	uncultured_Mediterranean_phage	8.7e-28	31.2
WP_002212289.1\|4262305_4263265_-	bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA	NA	NA	NA	NA
WP_002212288.1\|4263261_4264299_-	UDP-N-acetylmuramate dehydrogenase	NA	NA	NA	NA
WP_002218887.1\|4269966_4270152_+	hypothetical protein	NA	NA	NA	NA
WP_002215920.1\|4270435_4270969_-	menaquinone-dependent protoporphyrinogen IX dehydrogenase	NA	NA	NA	NA
WP_002211550.1\|4270990_4272442_-	Trk system potassium transporter TrkH	NA	NA	NA	NA
WP_002213759.1\|4273030_4273489_-\|transposase	IS200/IS605-like element IS1541A family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr_ID: NZ_CP045145.1|WP_002214494.1|2391430_2391787_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_CP045145.1|WP_002214494.1|2391430_2391787_-|hypothetical-protein

2391430_2391787_-

118 aa aa

2328663-2437794

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP045145_2	Orphan	2.4\|1268032\|32\|NZ_CP045145\|CRISPRCasFinder,CRT	1268032-1268063	32	2420513-2420482	0
NZ_CP045145_3	TypeI-F	3.1\|1877685\|32\|NZ_CP045145\|PILER-CR,CRISPRCasFinder,CRT	1877685-1877716	32	2426048-2426079	0

1. spacer 2.4|1268032|32|NZ_CP045145|CRISPRCasFinder,CRT matches to NZ_CP045145 position: 2420513-2420482, mismatch: 0

agactgatgcaagatggcggtatgcgtacaga	CRISPR spacer
agactgatgcaagatggcggtatgcgtacaga	Protospacer
********************************

2. spacer 3.1|1877685|32|NZ_CP045145|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045145 position: 2426048-2426079, mismatch: 0

ctgatgggtaactttaatcccaaattcttttt	CRISPR spacer
ctgatgggtaactttaatcccaaattcttttt	Protospacer
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Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP045147

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP045146

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_CP045145

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information