CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP045155	Yersinia pestis strain SCPM-O-B-5935 (I-1996) plasmid pMT, complete sequence	0 crisprs	NA	0	0	1	0
NZ_CP045154	Yersinia pestis strain SCPM-O-B-5935 (I-1996) chromosome, complete genome	5 crisprs	csa3,cas3,DinG,DEDDh,cas6f,cas7f,cas5f,cas8f,cas3f,cas1	1	10	13	1
NZ_CP045156	Yersinia pestis strain SCPM-O-B-5935 (I-1996) plasmid pCD, complete sequence	0 crisprs	NA	0	0	1	0
NZ_CP045157	Yersinia pestis strain SCPM-O-B-5935 (I-1996) plasmid pPCP, complete sequence	0 crisprs	NA	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 96100

Salmonella_phage(78.38%)

integrase,terminase,tail,transposase

attL 13549:13566|attR 26607:26624

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002214164.1\|0_1065_+	replication protein RepA	J9Q7H0	Salmonella_phage	2.4e-188	98.6
WP_002222711.1\|1633_1846_-	hypothetical protein	J9Q7S8	Salmonella_phage	6.8e-34	95.7
WP_002227818.1\|1845_2181_-	hypothetical protein	J9Q7Z5	Salmonella_phage	5.2e-52	91.0
WP_002228796.1\|2177_2357_-	hypothetical protein	J9Q6J1	Salmonella_phage	5.8e-18	86.4
WP_002228797.1\|2397_2673_-	hypothetical protein	J9Q738	Salmonella_phage	1.7e-45	95.6
WP_002222869.1\|2740_3151_-	hypothetical protein	J9Q7G9	Salmonella_phage	4.1e-75	97.8
WP_002222868.1\|3134_3506_-	DUF2591 domain-containing protein	J9Q7S7	Salmonella_phage	4.0e-61	87.8
WP_002222866.1\|3659_4490_-	hypothetical protein	J9Q7Z4	Salmonella_phage	9.3e-127	98.6
WP_002213439.1\|4493_4694_-	hypothetical protein	J9Q6J0	Salmonella_phage	1.1e-25	97.0
WP_161597819.1\|4784_5816_-	recombinase	J9Q736	Salmonella_phage	6.9e-196	99.1
WP_000920226.1\|5863_6130_-	hypothetical protein	J9Q7G8	Salmonella_phage	1.6e-40	100.0
WP_002225551.1\|6129_7074_-	exonuclease	J9Q7S6	Salmonella_phage	1.3e-180	99.0
WP_002213132.1\|7134_8163_-	hypothetical protein	J9Q7Z3	Salmonella_phage	1.3e-165	98.5
WP_011114024.1\|8282_8714_-	hypothetical protein	J9Q6I8	Salmonella_phage	2.2e-71	97.9
WP_002215095.1\|8934_9186_+	hypothetical protein	NA	NA	NA	NA
WP_002213141.1\|9258_9822_+	DNA-binding protein	J9Q7G7	Salmonella_phage	2.2e-63	64.6
WP_002425587.1\|9851_10277_-	hypothetical protein	J9Q7S4	Salmonella_phage	7.5e-72	100.0
WP_002221186.1\|10291_13816_-	DNA polymerase III subunit alpha	J9Q7Z2	Salmonella_phage	0.0e+00	99.2
13549:13566	attL	NA	NA	NA	NA
WP_002211767.1\|13996_15232_-	AAA domain-containing protein	J9Q733	Salmonella_phage	3.0e-238	99.3
WP_002211766.1\|15328_17695_-	porphyrin biosynthesis protein	J9Q7G6	Salmonella_phage	0.0e+00	94.4
WP_002228800.1\|17804_18017_-	hypothetical protein	NA	NA	NA	NA
WP_002228802.1\|18279_18666_+	hypothetical protein	NA	NA	NA	NA
WP_002353208.1\|18660_19764_-\|integrase	site-specific integrase	A0A1P8DTG6	Proteus_phage	5.2e-24	30.9
WP_002216410.1\|20523_21036_-	F1 capsule protein	NA	NA	NA	NA
WP_002211763.1\|21116_23618_-	F1 capsule-anchoring protein	NA	NA	NA	NA
WP_002211762.1\|23642_24419_-	chaperone Caf1M	NA	NA	NA	NA
WP_002211761.1\|24746_25652_+	F1 operon transcriptional regulator Caf1R	NA	NA	NA	NA
WP_002224363.1\|26166_26472_-	hypothetical protein	J9Q7S1	Salmonella_phage	3.2e-48	97.0
WP_002224361.1\|26617_26833_-	hypothetical protein	J9Q6I3	Salmonella_phage	7.7e-33	98.6
26607:26624	attR	NA	NA	NA	NA
WP_002233024.1\|26992_28030_-	DNA ligase	J9Q7G5	Salmonella_phage	1.8e-207	99.4
WP_001297096.1\|28105_28885_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_000255944.1\|28884_29907_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_002224267.1\|30308_30566_-	hypothetical protein	J9Q7R9	Salmonella_phage	1.3e-34	94.1
WP_002224265.1\|30866_31661_-	hypothetical protein	J9Q7Z0	Salmonella_phage	3.7e-141	96.6
WP_002224263.1\|31913_32636_+	DUF4145 domain-containing protein	NA	NA	NA	NA
WP_002209743.1\|32669_33878_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_002211760.1\|34346_35369_+\|transposase	IS110-like element IS1618 family transposase	NA	NA	NA	NA
WP_002211758.1\|37444_39208_-	phospholipase D	NA	NA	NA	NA
WP_002211757.1\|39285_39774_-	phospholipase D family protein	NA	NA	NA	NA
WP_002211756.1\|40512_40788_+	hypothetical protein	NA	NA	NA	NA
WP_002215065.1\|40810_41752_-\|transposase	Rpn family recombination-promoting nuclease/putative transposase	Q2A0A7	Sodalis_phage	1.0e-68	54.8
WP_002211754.1\|41817_42438_-	recombinase family protein	A0A1V0E035	Clostridioides_phage	6.5e-08	31.1
WP_002215068.1\|42637_42964_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_002211753.1\|42963_43191_-	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
WP_002211752.1\|43492_44698_+	ParA family protein	Q1MVJ3	Enterobacteria_phage	1.7e-206	90.5
WP_002215070.1\|44694_45666_+	ParB/RepB/Spo0J family partition protein	Q1MVJ4	Enterobacteria_phage	1.5e-112	67.3
WP_002228775.1\|46044_47442_+	AAA family ATPase	NA	NA	NA	NA
WP_002211750.1\|47603_47804_-	hypothetical protein	NA	NA	NA	NA
WP_002211749.1\|48304_48982_+	DNA methylase	A0A2I7RE86	Vibrio_phage	1.6e-28	36.9
WP_002211748.1\|48981_49203_+	hypothetical protein	NA	NA	NA	NA
WP_002215082.1\|49213_49633_+	DUF1380 domain-containing protein	NA	NA	NA	NA
WP_002211747.1\|49686_50466_+	hypothetical protein	NA	NA	NA	NA
WP_002211746.1\|50864_51371_+	antirestriction protein	A0A1I9S7Y0	Rhodococcus_phage	1.1e-08	29.5
WP_002211745.1\|52083_52314_+	DUF905 domain-containing protein	NA	NA	NA	NA
WP_002211744.1\|52386_54396_+	ParB/RepB/Spo0J family partition protein	G8DH78	Emiliania_huxleyi_virus	7.7e-26	30.3
WP_000255944.1\|54519_55542_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_001297096.1\|55541_56321_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_002211769.1\|56450_57059_-\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	4.8e-64	62.2
WP_002211770.1\|57360_60249_-\|tail	phage tail protein	J9Q6E3	Salmonella_phage	4.5e-11	33.1
WP_002211771.1\|60329_60908_-	DUF4376 domain-containing protein	Q9LA61	Enterobacterial_phage	3.4e-27	38.8
WP_002214118.1\|60964_65596_-	DUF1983 domain-containing protein	J9Q713	Salmonella_phage	0.0e+00	88.6
WP_002211773.1\|65617_66205_-\|tail	tail assembly protein	J9Q7F8	Salmonella_phage	5.1e-103	92.8
WP_002211774.1\|66192_66990_-\|tail	tail protein	J9Q7R4	Salmonella_phage	1.4e-156	96.2
WP_002211775.1\|66982_67681_-\|tail	phage minor tail protein L	J9Q7Y5	Salmonella_phage	7.1e-136	99.1
WP_000440566.1\|67770_68106_-\|tail	phage tail protein	J9Q6E1	Salmonella_phage	5.7e-59	97.3
WP_002211776.1\|68147_72725_-	tape measure protein	J9Q712	Salmonella_phage	0.0e+00	90.5
WP_000952684.1\|72732_72957_-	hypothetical protein	J9Q7F7	Salmonella_phage	4.2e-34	100.0
WP_000163862.1\|73082_73400_-	hypothetical protein	J9Q7R3	Salmonella_phage	6.0e-50	98.1
WP_002211778.1\|73459_74206_-	Ig domain-containing protein	J9Q7Y4	Salmonella_phage	5.2e-129	98.8
WP_002211779.1\|74280_74664_-	hypothetical protein	J9Q6D8	Salmonella_phage	1.1e-66	98.4
WP_002211780.1\|74665_75139_-	hypothetical protein	J9Q711	Salmonella_phage	8.9e-82	99.4
WP_001027662.1\|75129_75474_-	hypothetical protein	J9Q7F6	Salmonella_phage	1.9e-57	100.0
WP_002211781.1\|75571_76405_-	hypothetical protein	J9Q7R2	Salmonella_phage	2.9e-152	99.6
WP_002211782.1\|76404_76839_-	hypothetical protein	J9Q7Y3	Salmonella_phage	3.1e-73	99.3
WP_002211783.1\|76882_77545_-	Ig domain-containing protein	J9Q6D6	Salmonella_phage	8.5e-107	97.2
WP_002211784.1\|77619_78495_-	hypothetical protein	J9Q710	Salmonella_phage	8.5e-163	99.7
WP_002211786.1\|79444_81019_-	hypothetical protein	J9Q7R1	Salmonella_phage	2.4e-301	99.2
WP_002211787.1\|81052_82309_-\|terminase	terminase	J9Q7Y2	Salmonella_phage	1.8e-251	100.0
WP_002211788.1\|82311_82953_-	hypothetical protein	J9Q6D4	Salmonella_phage	1.2e-108	98.1
WP_000176291.1\|83148_83415_-	hypothetical protein	J9Q757	Salmonella_phage	1.3e-42	100.0
WP_002211789.1\|83424_84315_-	hypothetical protein	J9Q7I6	Salmonella_phage	6.2e-169	99.7
WP_002211790.1\|84320_84575_-	hypothetical protein	J9Q7U0	Salmonella_phage	2.0e-40	97.6
WP_002211791.1\|84567_85206_-	ATP-binding cassette domain-containing protein	J9Q807	Salmonella_phage	4.7e-110	98.1
WP_002211792.1\|85202_85871_-	ParB N-terminal domain-containing protein	J9Q6L1	Salmonella_phage	9.5e-114	98.2
WP_002228791.1\|85870_86569_-	ParB N-terminal domain-containing protein	J9Q756	Salmonella_phage	9.6e-125	98.7
WP_002211794.1\|86633_88193_+	DEAD/DEAH box helicase	J9Q7I4	Salmonella_phage	1.1e-293	99.0
WP_002214131.1\|88195_88474_+	hypothetical protein	J9Q7T9	Salmonella_phage	4.4e-41	97.8
WP_002211796.1\|88533_88956_+	hypothetical protein	J9Q806	Salmonella_phage	4.1e-62	85.0
WP_002214134.1\|88960_89488_+	transcriptional regulator	J9Q6L0	Salmonella_phage	6.4e-81	98.0
WP_002211799.1\|89811_90462_+	hypothetical protein	J9Q754	Salmonella_phage	4.1e-114	99.5
WP_002214137.1\|90546_90774_+	hypothetical protein	NA	NA	NA	NA
WP_002213775.1\|90883_91342_-\|transposase	IS200/IS605-like element IS1541B family transposase	D9CGB6	Hyperthermophilic_Archaeal_Virus_2	5.0e-13	35.3
WP_002214145.1\|91550_92120_-	hypothetical protein	J9Q7Z7	Salmonella_phage	5.8e-104	100.0
WP_002213303.1\|92132_92879_-	hypothetical protein	J9Q6J5	Salmonella_phage	4.1e-134	96.4
WP_002213300.1\|95014_96100_-	exonuclease	J9Q7S9	Salmonella_phage	7.7e-206	98.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP045154

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP045154_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045154_1

259346-259458

Orphan

Consensus_repeat	Method
CTTCACTCGGCTGCTCAAATGTGCTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045154_1

>merge|NZ_CP045154|1|259346-259458|CRISPRCasFinder
CTTCACTCGGCTGCTCAAATGTGCTTTGGACGTCAACAACCCATTCAAAATCAAAAACGTATTAAAAGCCTAAGGATGATGGTCTGGCTTCACTCGCTGCTCAAATGTGCTTT

>NZ_CP045154|1|1|259346-259458|CRISPRCasFinder
CTTCACTCGGCTGCTCAAATGTGCTTT	GGACGTCAACAACCCATTCAAAATCAAAAACGTATTAAAAGCCTAAGGATGATGGTCTG
GCTTCACTCGCTGCTCAAATGTGCTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045154.1\|WP_002209489.1\|264301_265306_+\|N-acetyl-gamma-glutamyl-phosphate-reductase	unknown	unknown	gnl\|CDD\|234761
NZ_CP045154.1\|WP_002208936.1\|251382_251838_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227027
NZ_CP045154.1\|WP_002208938.1\|248183_250382_-\|primosomal-protein-N'	unknown	unknown	gnl\|CDD\|235514
NZ_CP045154.1\|WP_100067904.1\|257781_259136_-\|IS3-like-element-IS1661-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP045154.1\|WP_002223919.1\|262887_264051_-\|acetylornithine-deacetylase	unknown	unknown	gnl\|CDD\|235346
NZ_CP045154.1\|WP_002208943.1\|243864_245196_-\|HslU--HslV-peptidase-ATPase-subunit	unknown	unknown	gnl\|CDD\|235364
NZ_CP045154.1\|WP_002216737.1\|250624_250840_+\|50S-ribosomal-protein-L31	unknown	unknown	gnl\|CDD\|234576
NZ_CP045154.1\|WP_002209488.1\|265474_266248_+\|acetylglutamate-kinase	unknown	unknown	gnl\|CDD\|239782
NZ_CP045154.1\|WP_002208934.1\|254043_256479_+\|bifunctional-aspartate-kinase/homoserine-dehydrogenase-II	unknown	unknown	gnl\|CDD\|236530
NZ_CP045154.1\|WP_002208942.1\|245266_245791_-\|ATP-dependent-protease-subunit-HslV	unknown	unknown	gnl\|CDD\|235477
NZ_CP045154.1\|WP_002209491.1\|259877_262514_-\|phosphoenolpyruvate-carboxylase	unknown	unknown	gnl\|CDD\|234570
NZ_CP045154.1\|WP_002209485.1\|268386_270879_+\|TonB-dependent-hemoglobin/transferrin/lactoferrin-family-receptor	unknown	unknown	gnl\|CDD\|273807
NZ_CP045154.1\|WP_002209482.1\|273767_275096_+\|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|130902
NZ_CP045154.1\|WP_002208935.1\|252186_252504_-\|met-regulon-transcriptional-regulator-MetJ	unknown	unknown	gnl\|CDD\|179982
NZ_CP045154.1\|WP_002209484.1\|271100_271718_+\|hemophore-HasA	unknown	unknown	gnl\|CDD\|368907
NZ_CP045154.1\|WP_002209487.1\|266414_267788_+\|argininosuccinate-lyase	unknown	unknown	gnl\|CDD\|179883
NZ_CP045154.1\|WP_002209481.1\|275160_275964_+\|energy-transducer-TonB	unknown	unknown	gnl\|CDD\|223880
NZ_CP045154.1\|WP_002208941.1\|245890_246736_-\|cell-division-protein-FtsN	unknown	unknown	gnl\|CDD\|237191
NZ_CP045154.1\|WP_002209483.1\|271883_273692_+\|type-I-secretion-system-permease/ATPase	unknown	unknown	gnl\|CDD\|226969
NZ_CP045154.1\|WP_002208933.1\|256711_257596_+\|methylenetetrahydrofolate-reductase	unknown	unknown	gnl\|CDD\|181852

Protein	Function_ID	Function_description	E-value
NZ_CP045154.1\|WP_002209489.1\|264301_265306_+\|N-acetyl-gamma-glutamyl-phosphate-reductase	gnl\|CDD\|234761	PRK00436, argC, N-acetyl-gamma-glutamyl-phosphate reductase; Validated.	0
NZ_CP045154.1\|WP_002208936.1\|251382_251838_-\|hypothetical-protein	gnl\|CDD\|227027	COG4682, COG4682, Predicted membrane protein [Function unknown].	3.96467e-66
NZ_CP045154.1\|WP_002208938.1\|248183_250382_-\|primosomal-protein-N'	gnl\|CDD\|235514	PRK05580, PRK05580, primosome assembly protein PriA; Validated.	0
NZ_CP045154.1\|WP_100067904.1\|257781_259136_-\|IS3-like-element-IS1661-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	9.01643e-48
NZ_CP045154.1\|WP_002223919.1\|262887_264051_-\|acetylornithine-deacetylase	gnl\|CDD\|235346	PRK05111, PRK05111, acetylornithine deacetylase; Provisional.	0
NZ_CP045154.1\|WP_002208943.1\|243864_245196_-\|HslU--HslV-peptidase-ATPase-subunit	gnl\|CDD\|235364	PRK05201, hslU, ATP-dependent protease ATPase subunit HslU.	0
NZ_CP045154.1\|WP_002216737.1\|250624_250840_+\|50S-ribosomal-protein-L31	gnl\|CDD\|234576	PRK00019, rpmE, 50S ribosomal protein L31; Reviewed.	4.16591e-39
NZ_CP045154.1\|WP_002209488.1\|265474_266248_+\|acetylglutamate-kinase	gnl\|CDD\|239782	cd04249, AAK_NAGK-NC, AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of ornithine biosynthesis. There are two variants of this pathway. In one, typified by the pathway in Escherichia coli, glutamate is acetylated by acetyl-CoA and acetylornithine is deacylated hydrolytically. In this pathway, feedback inhibition by arginine occurs at the initial acetylation of glutamate and not at the phosphorylation of NAG by NAGK. Homodimeric NAGK-NC are members of the Amino Acid Kinase Superfamily (AAK).	2.92616e-136
NZ_CP045154.1\|WP_002208934.1\|254043_256479_+\|bifunctional-aspartate-kinase/homoserine-dehydrogenase-II	gnl\|CDD\|236530	PRK09466, metL, bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional.	0
NZ_CP045154.1\|WP_002208942.1\|245266_245791_-\|ATP-dependent-protease-subunit-HslV	gnl\|CDD\|235477	PRK05456, PRK05456, ATP-dependent protease subunit HslV.	1.88144e-131
NZ_CP045154.1\|WP_002209491.1\|259877_262514_-\|phosphoenolpyruvate-carboxylase	gnl\|CDD\|234570	PRK00009, PRK00009, phosphoenolpyruvate carboxylase; Reviewed.	0
NZ_CP045154.1\|WP_002209485.1\|268386_270879_+\|TonB-dependent-hemoglobin/transferrin/lactoferrin-family-receptor	gnl\|CDD\|273807	TIGR01785, Heme/hemopexin_utilization_protein_C, TonB-dependent heme/hemoglobin receptor family protein. This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins].	8.20794e-132
NZ_CP045154.1\|WP_002209482.1\|273767_275096_+\|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit	gnl\|CDD\|130902	TIGR01843, Hemolysin_secretion_protein_D_plasmid, type I secretion membrane fusion protein, HlyD family. Type I secretion is an ABC transport process that exports proteins, without cleavage of any signal sequence, from the cytosol to extracellular medium across both inner and outer membranes. The secretion signal is found in the C-terminus of the transported protein. This model represents the adaptor protein between the ATP-binding cassette (ABC) protein of the inner membrane and the outer membrane protein, and is called the membrane fusion protein. This model selects a subfamily closely related to HlyD; it is defined narrowly and excludes, for example, colicin V secretion protein CvaA and multidrug efflux proteins. [Protein fate, Protein and peptide secretion and trafficking].	3.16318e-105
NZ_CP045154.1\|WP_002208935.1\|252186_252504_-\|met-regulon-transcriptional-regulator-MetJ	gnl\|CDD\|179982	PRK05264, PRK05264, met regulon transcriptional regulator MetJ.	5.3482e-81
NZ_CP045154.1\|WP_002209484.1\|271100_271718_+\|hemophore-HasA	gnl\|CDD\|368907	pfam06438, HasA, Heme-binding protein A (HasA). Free iron is limited in vertebrate hosts, thus an alternative to siderophores has been developed by pathogenic bacteria to access host iron bound in protein complexes. HasA is a secreted hemophore that has the ability to obtain iron from hemoglobin. Once bound to HasA, the heme is shuttled to the receptor HasR, which releases the heme into the bacterium.	9.51098e-102
NZ_CP045154.1\|WP_002209487.1\|266414_267788_+\|argininosuccinate-lyase	gnl\|CDD\|179883	PRK04833, PRK04833, argininosuccinate lyase; Provisional.	0
NZ_CP045154.1\|WP_002209481.1\|275160_275964_+\|energy-transducer-TonB	gnl\|CDD\|223880	COG0810, TonB, Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane].	1.51188e-39
NZ_CP045154.1\|WP_002208941.1\|245890_246736_-\|cell-division-protein-FtsN	gnl\|CDD\|237191	PRK12757, PRK12757, cell division protein FtsN; Provisional.	2.3223e-148
NZ_CP045154.1\|WP_002209483.1\|271883_273692_+\|type-I-secretion-system-permease/ATPase	gnl\|CDD\|226969	COG4618, ArpD, ABC-type protease/lipase transport system, ATPase and permease components [General function prediction only].	0
NZ_CP045154.1\|WP_002208933.1\|256711_257596_+\|methylenetetrahydrofolate-reductase	gnl\|CDD\|181852	PRK09432, metF, methylenetetrahydrofolate reductase.	0

>NZ_CP045154.1|WP_100067904.1|257781_259136_-|IS3-like-element-IS1661-family-transposase
MKHPFSTRLAAVQHYLSGKATLRETARQFSVGKSPLTRWIRAFRRQGEAGLEHHLSRTYTPEFRLCVVRYMMANRCSAADASAHFNIPNETIIQNWMKRYREGGKEALNPSKTGPTMPKDKYEHDSKPFSEMTHAELEKELEYLRAENAYPKKAESPERRKGTQGAAEKTRIVQALTAEHRLSCLLCAAKLARSTYYYHASKPDGVIDDYADAVKAIGALSRRHAQRYGYRRMTVALRKEGFTLNHKTVRKLMNQHGLLSLIRRKKYRSYRADGGRASDNLLARNFTSEISGLKWCTDVTEFRVGAQKLYLSVIQDLFNNEIISWHMSERAALILTCKTLEKALKVKGRKEGLMLHSDQGWHYRTPMWRSMLVEAGIRQSMSRKGNCLDNAVMENFFSHLKAEMYHRKKYDSATVLKRDIVEYIHYYNTERISLKTGGMSPAEYRTQVEKQ
>NZ_CP045154.1|WP_002208933.1|256711_257596_+|methylenetetrahydrofolate-reductase
MSFFHANQREALNQSLSELQGQINVSFEFFPPRTSEMEDTLWSSIDRLSTLKPKFVSVTYGANSGERDRTHSIIKGIKERTGLEAAPHLTCIDASPTQLRDIAIDYWNSGIRHIVALRGDLPPNSGKPEMYACDLVGLLKDVGDFDISVAAYPEIHPEAKSAQADLINLKRKIDAGANRAITQFFFDVESYLRFRDRCVATGIDVEIVPGILPVSNFKQLQRFATMTNVRVPNWMTSIFDGLDNDPETRKMVGASVAMDMVKILSREGVKDFHFYTLNRAELSYAICHTLGVRP
>NZ_CP045154.1|WP_002208934.1|254043_256479_+|bifunctional-aspartate-kinase/homoserine-dehydrogenase-II
MNATAVAAAATGRQLHKFGGSSLADVKCYLRVANIMANYSHPGDLMVVSAAGSTTNQLISWLKLSQNDRLSAHQVQQSLRRYQHDLINGLLPPEMAEPLISEFIHDLERLAGLLDNKIDDVIYAEVVGHGEIWSARLMSALLNKLDMDAVWLDARRFLRAERAAQPQIDESRSYPLLQQLMAQHPHQRLVVTGFISRNEAGETVLLGRNGSDYSATQVGALAGAERVTIWSDVAGVYSADPRKVKDACLLPLLRLDEASELARLAAPVLHTRTLQPVSGSDIDLQLRCSYQPEQGSTRIERVLASGLGAKIVTSHDDVCLIELQIASHHDFSLAQKEIDLLLKRAQIKPLATGIHPDRNLLQLCYTSEVVNSALRVLEDAALPGKLSLREGLALVALVGAGVSKNPLHSHRFYQQLKDQPVEFVWQAEDGISMVAVLRLGPTEHLIQGLHQSLFRAEKRIGLMLFGKGNIGARWLELFAREQKSLSARSGFEFVLAGVVDSRRSLLSYDGLDASRTLAFYNDEAKEQDEESLFLWMRAHPFDDLVVLDVTASPSLAEQYLDFASYGFHVISANKLAGASSSNNYRQIRDAFAKTGRHWLYNATVGAGLPVNHTVRDLRDSGDSILAISGIFSGTLSWLFLQFDGSVPFTELVDQAWQQGLTEPDPRVDLSGQDVMRKLVILAREAGYDIEPNQVRVESLVPAGAESGSVDQFFENGEALNQQMIQRLEAAKEMGLVLRYVARFDANGKARVGVEAVRTDHPLASLLPCDNVFAIESRWYRDNPLVIRGPGAGRDVTAGAIQSDLNRLSQLL
>NZ_CP045154.1|WP_002208935.1|252186_252504_-|met-regulon-transcriptional-regulator-MetJ
MAEWNGEYVSPYAEHGKKSKQVKKITVSIPLKVLKILTDERTRRQVNNLRHATNSELLCEAFLHAFTGQPLPNDEDLRKERSDEIPEAAKILMRELGVDPDTWEY
>NZ_CP045154.1|WP_002208936.1|251382_251838_-|hypothetical-protein
MNPNYAKPSAAFTAASWSALLGGFVIFLIGLWNADMQLNERGYYFAVLILGLFSAVSLQKTVRDKLEGLAITSIYYGLCWVAFIVAVLLLCIGLWNATLALSEKGFYGVTFFMTLFGAIAVQKNTRDSAMSSDTESASLFKKVRDQLKAED
>NZ_CP045154.1|WP_002216737.1|250624_250840_+|50S-ribosomal-protein-L31
MKQGIHPKYEQVTASCSCGNVIKINSTVGHDLNLDVCGECHPFYTGKQRDVASGGRVDRFNKRFSVPGAKK
>NZ_CP045154.1|WP_002208938.1|248183_250382_-|primosomal-protein-N'
MSVVQVALPVPLARTFDYRLDSAMACPVVGARVSVPFGKRKAIGIVVGLSDTSTFPLEQLKTIDAILDNHSLFPPSLWRILCWATEYYHYPIGEVLFHALPILLRQGRPAQSAPLWQWFVTEQGRATPPESLKRAPKQQQALAALLQKPVYRHQVNEMALTESALQALRSKGLIDLRAQEATTTDWRHSFSVLGERLRLNTEQATAVGAIRSEDNQFAAWLLAGVTGSGKTEVYLSVLENILAQGRQALILVPEIGLTPQTIARFRERFNAPVEVLHSGLNDSERLSVWLRARSGEAAIVIGTRSALFTPFSRLGVIIIDEEHDSSYKQQEGWRYHARDLAVFRAREEGIPIVMGTATPALETLHNVQMGKYRQLTLTKRAGSAKPAAQHLLDLKGLPLKVGLSQPLLKQMKTHLQAGNQVILFLNRRGYAPALLCHECGWIAECQRCDHYYTLHQNHRQLRCHHCDSQRPVPQQCPKCGSTHLVSVGVGTEQLENELAPLFPETPITRIDRDTTSRKGSLEQYLADVHQGGARILIGTQMLAKGHHFPDVTLVALLDVDGALFSADFRSAERFAQLYTQVSGRAGRAGKQGEVILQTHHPEHPLLQILLQQGYDAFAKQALEERKSVFLPPYTSHIIVRSEDHDNQQSALFLQQLRNLLEASPLKDEALWIMGPVPALQAKRGGRFRWQLLLQHPSRQLLQRLIKTSQPLISTLPQARKVKWTIDVDPIDS
>NZ_CP045154.1|WP_002208941.1|245890_246736_-|cell-division-protein-FtsN
MAQRDYVSRGRSGARRKSTSRKKRSAPIVSKTVMALAVALLVVFVGGLYFITHNKPGELPLLPNHDPRTGNGLPPKPEERWRYIKELENRQIGVPMPTEPSAGGEVNAKTELTNEQRQLLEQMQADMRQQPTQLSEVPYNQGMQQVPRSAVTIKPPATSVQPQPVTPPRQTTIPVQPQAPAPVRTPPAAPVTQAVTPPKVEKEKEKTQRWMVQCGSFKAVDQAESIRAQLAFAGIESRITSGGGWNRVVLGPYNSKAAADKALQRLQGAGQSGCIPLSVGG
>NZ_CP045154.1|WP_002208942.1|245266_245791_-|ATP-dependent-protease-subunit-HslV
MTTIVSVRRDGHVVIGGDGQVTLGNTVMKGNAKKVRRLYNNKVIAGFAGGTADAFTLFELFERKLEMHQGHLTKAAVELAKDWRTDRMLRKLEALLAVADETASLIITGNGDVVQPEDDLIAIGSGGPYAQSAARALLENTELGARDIVEKSLSIAGDICIYTNRFQTIEELTY
>NZ_CP045154.1|WP_002208943.1|243864_245196_-|HslU--HslV-peptidase-ATPase-subunit
MSEMTPREIVSELDSHIIGQDKAKRAVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRDLTDAAVKMVRHQSIEKMRYRAEELAEERILDVLIPPAKNNWGVPDESQEPSATRQTFRKKLREGQLDDKEIEIDLAAAPMGVEIMAPPGMEEMTNQLQSMFQNIAGQKQKPRKIKIKEALKLLIEEEAAKLVNPEELKQQAIDAVEQHGIVFIDEIDKICKRGQTSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQVSSPSDLIPELQGRLPIRVELQALTTDDFERILTEPSASLTEQYKALMATEGVTIEFTREGIRKIAEAAWQVNERTENIGARRLHTVLERLMEDISYDASESSGQSITIDAEYVGKHLDELVADEDLSRFIL
>NZ_CP045154.1|WP_002209491.1|259877_262514_-|phosphoenolpyruvate-carboxylase
MNEQYSAMRSNVSMLGTLLGDTIKEALGEHILDRVETIRKLSKSSRAGNEASRQELLTTLQNLSNDELLPVARAFSQFLNLTNTAEQYHSISPHGEAASNPEALAQLFTRLKDKKLSDQDMRSAVDDLSIELVLTAHPTEITRRTLIHKLVEVNTCLSQLDHNDLADYERNKIMRRLRQLVAQSWHTDEIRKLRPSPVDEAKWGFAVVENSLWEGVPAFLREFNEQLENSLDYRLPVEAVPIRFTSWMGGDRDGNPNVTAEITRHVLLLSRWKATDLFLRDIQVLVSELSMSECTPELRELAGGEEVLEPYRQLMKNVRTQLTNTQAYLEARLKGERVLPPHDLLVSNDQLWEPLYACYQSLKACGMEIIANGQLLDTLRRVRCFGVPLVRIDVRQESTRHTDAIAELTRYLGLGDYESWSESDKQAFLVRELNSKRPLVPLKWEPSAETQEVLETCRVIAEAPQGSIAAYVISMAKVPSDVLAVHLLLKEAGCPFTLPVAPLFETLDDLNNADDVMTQLLGIDWYRGLIQGKQMVMIGYSDSAKDAGVMAASWAQYRAQDALIKTCEKAGITLTLFHGRGGSIGRGGAPAHAALLSQPPGSLKGGLRVTEQGEMIRFKFGLPEVTISSLALYAGAILEANLLPPPEPKKEWIEVMDLLSDASCDMYRSYVRENPEFVRYFRAATPELELGKLPLGSRPAKRRPDGGVESLRAIPWIFAWTQNRLMLPAWLGAGAGLQRAIDAGKQDVLATMCRDWPFFSTRIGMLEMVFAKADLWLAEYYDQRLVDKSLWPLGQQLRDQLAADIKVVLAIANDDHLMADLPWIAESIALRNVYTDPLNVLQAELLHRSRQQEHPDACVEQALMVTIAGVAAGMRNTG
>NZ_CP045154.1|WP_002223919.1|262887_264051_-|acetylornithine-deacetylase
MKLPPFIELYRALIATPSISAADSALDQSNEALINLLAGWFADLGFRVEIQPVPDTRHKFNLLASIGENENGEGHGGLLLAGHTDTVPYDEGRWTRDPFTLTEHDHKLYGLGTADMKGFFAFILDAVRDIDASKLTKPLYILATADEETTMAGARYFAANTQLRPDFAIIGEPTSLQPVRAHKGHISNAIRITGQSGHSSDPARGVNAIDLMHESITQLMALRTTLQERYHNPAFTIPYPTMNFGHINGGDAANRICACCELHMDIRPLPGLTLSDLNELMTEALEPVSQRWPGRLSIDELHPPIPGYECPTDHHMVGVIEKLLGERTAVVNYCTEAPFIQQVCPTLVLGPGSINQAHQPDEFIDMAFIEPTRELIGQLVDHFCQQK
>NZ_CP045154.1|WP_002209489.1|264301_265306_+|N-acetyl-gamma-glutamyl-phosphate-reductase
MLNTLIVGASGYAGAELTAYLNRHPHMNITGLAVSAQSADAGKLLSDLHPQLKGILDLPLQPLVDVAQAAKGIDVVFLATAHEVSHDLAPQFLAAGCVVFDLSGAFRVRDAAFYSQYYGFEHQHPDWLDKAVYGLAEWQSEDIKQAQLIAVPGCYPTASQLALKPLVDGQLLNDAQWPVINAVSGVSGAGRKASMGNSFCEVSLQPYGLFTHRHQPEIVTHLGTPVIFTPHLGNFARGILATITCRLKAGVTAQNIADAYHHAYQNKPLVRLYQQGVPALKAVVGLPFCDIGFSVQGEHLIIVATEDNLLKGAAAQAVQCMNIRFGFPETQSLL
>NZ_CP045154.1|WP_002209488.1|265474_266248_+|acetylglutamate-kinase
MNPLVIKLGGVLLDSEEALERLFTALVTYREKHERPLVIMHGGGCLVDELMKRLALPVVKKNGLRVTPADQIDIITGALAGTANKTLLAWAVKHQINAVGLCLADGNTVTVTLLDAELGHVGKAQPGSAALVQTLLAAGYMPIISSIGITVEGQLMNVNADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTAQKAEQLIAQGIITDGMVVKVNAALDAARSLGRPVDIASWRHSEQLPALFNGVPIGTRISV
>NZ_CP045154.1|WP_002209487.1|266414_267788_+|argininosuccinate-lyase
MALWGGRFSQAADQRFKQFNDSLRFDYRLAEQDIIGSVAWSKALVTVGVLNADEQQQLEQALSVLLEEVQANPHAILASDAEDIHSWVETKLIDKVGDLGKKLHTGRSRNDQVATDLKLWCKFQITELQTAVQQLQQALVMTAEANQDAVMPGYTHLQRAQPVTFAHWCLAYVEMLSRDESRLQDTLKRLDVSPLGCGALAGTAYAIDREQLAGWLGFASATRNSLDSVSDRDHVLELLSDASIGMVHLSRFAEDLIFFNSGEAAFVDLSDRVTSGSSLMPQKKNPDALELIRGKCGRVQGALTGMTMTLKGLPLAYNKDMQEDKEGLFDALDTWLDCLHMAALVLDGIQVKRPRCKEAAEQGYANATELADYLVAKGVPFREAHHIVGEAVVEAIRQGKALEALALSDLQQFSSVIGDDVYPILALQSCLDKRVAKGGVSPQQVASAIAEAKARLF
>NZ_CP045154.1|WP_002209485.1|268386_270879_+|TonB-dependent-hemoglobin/transferrin/lactoferrin-family-receptor
MDNIIRDKKTIISVNKITTCILFALVTQGYSGQLAANTAETPTNNNDMALDKLNVEGKGNAHDSDWIYDEPRSVSEITREQLDNRPARHAADILEQTPGVYSSVSQQDPGLSINIRGIQDYGRVNMNIDGMRQNFMKSGHGQRNGSMYIDPEILSNVVIERGIFNGIGGAGAIGGIATFNTINASDFLAPEKELGGHIRAMTGDNGTRFIGSGALALGNPNGDILLAVSERNLKDYWPGNKGVLAGLRLYSPTRNVGDDLKNTKTLFTGYKMRSQLAKVGWNFEAGQRLEFSYLQTQIASPNASMLSEVLALSPSGKEITKIGWRNTSFTNVENRNIALDYRLNPEHISWLDATAKIYYVDTNDETDNANSLFKEYFWTQTRLKTRGLQLQNTNTFTPSDAHQIRLKYGLEWFSDKSEGYSTRKLIERTTPPGKRAITSTFAQLNYEYDDWLRLEGGLRYDQFRLKGNTWLHTRSFLQPYTFENPCDRRIHEQSEKPGSRCSSRRPATMRWDVDRCEQQLSPTLAMGVKPGLEWLEFFGSYGKSWRPPAMTEVLATGTAHGYSWVLPNPFVAAERARTWEAGFNIQQSNLFIEDDHFAAKVAYFDTRIANYINLELGKAKPKFGGDSFTDVAYVNNLLKTRFRGLEYQLSYDAGTFYTNINYTRMIGVNNVCSPYAWLGGLQSVKYKYVGKVEQIYAVENEVANNYVTCMNANVLFGSSAYLPGDRGSLTLGSRIFDRRLDFGTVIRYNKGYQDRSAQDENGNPLTAYVADWPKYIVYDLYASYKVTNNLILRSSIENITNRAYLVNYGDTLSFAPSRGRTIQGGFEYKF
>NZ_CP045154.1|WP_002209484.1|271100_271718_+|hemophore-HasA
MSTTIQYNSNYADYSISSYLREWANNFGDIDQAPAETKDRGSFSGSSTLFSGTQYAIGSSHSNPEGMIAEGDLKYSFMPQHTFHGQIDTLQFGKDLATNAGGPSAGKHLEKIDITFNELDLSGEFDSGKSMTENHQGDMHKSVRGLMKGNPDPMLEVMKAKGINVDTAFKDLSIASQYPDSGYMSDAPMVDTVGVVDCHDMLLAA
>NZ_CP045154.1|WP_002209483.1|271883_273692_+|type-I-secretion-system-permease/ATPase
MESCKTPGASSVPPTILSVLAGNKKILWGIGLFTAVINLLMLAPAIYMLQVYDRVLASANTMTLLMLTVLVLGVFVFIGLLEWVRSAVVIRLGTQIDMQLNQPVFNAAFAANLKGHNTPAAQALNDLTVLRQFATGNALFAFFDAPWFPLYLLVIFLLHPWLGMLAAAGAGILVVLAWLNQWICKKPLHDASIITSHATQQANANLRNADVIEAMGMLKALRERWLMQHANFLYQQNLASDKSSRVTAVAKSSRQALQSMMLGLGALLVIYNEITAGVMIAGSILIGRVLGPIDQLIAVWKQWSHARLAYQRLSQLLAQHPSSPTGMVLPAPQGKLNVTQLMACKPGTHIPVLHSINFELQPGDVLGILGPSGSGKSTLAKLLVASQPTFSGTVRLDSADLSRWDKTQLGEFIGYLPQNIQLFRGTVAENIARFGAIDTAKVVAAAQLADVHDLILHLPQGYDTPLGDDGEGLSGGQRQRIALARAMYGIPRLIVLDEPNASLDKEGEQALLASIIQLKQQGCTIVMITHKPELLSGSDYLLFLKNGQMDLFDRTQAVLQNIQGKDKPAVQPEAKILNSRSGWSNGVSYGIGPARTTSSPKP
>NZ_CP045154.1|WP_002209482.1|273767_275096_+|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit
MLPESVCYSVANANRQPPLQINSGRYLNIGGGLVVIGFIGFLLWAGLAPLDKGVAVTGLLVVAENRKVIQPLQGGRIQQLHVTEGDEIVSGQLLVTLDDTAIRNQRDNLQHQYLSALAQEARLTAEQNDLDVITFPQALLEHATQPAVERNIILQQQLLHHRRQAHLSEIARLSTQLTRHQARLDGLQAMRSNHQRQSNLFQQQLDSVQLLAKDGHIAKNKLLEMESQSTSLQARVEQSTSDIAEAHKLIDETEQHVLQRREQYQSENSEQLAKAQQNTQELVQRLNIAEYELSHTRIFAPVSGSVIALAQHTVGGVVSSGQALMEIVPSGQPLFVEAQLPVELIDKVAVGLPVDLNFSAFNQSNTPRLQGSVWRIGADRIQPPPTSPPYYPLTVAIDLDPTELAIRPGMAVDVFIRTGERSLLSYLFKPFTDRLHLALAEE
>NZ_CP045154.1|WP_002209481.1|275160_275964_+|energy-transducer-TonB
MNRLQQSSDKLIFWLVGALLACGIHIYALWWLSTASIPAIPTSYPAAIMMELSAEPEFMQNLPQNSVVGITQNIIEPAVEQRVNQPDDIVDLPTLPEQPEGQREITRKEPIKVKRPAENRATSRKPVNKETQESDSKQSSPAAAASAMLSGTSQQVAAAVNSDSSHRQQAQVSWKSRLQGHLMGFKRYPSSARKQQQQGTAMIRFVVDKNGYVSSVQLSHSSGTSALDREALAIIKRAQPLPKPPAELLSQGQITLSLPVDFNLKRK

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Crispr_ID: NZ_CP045154_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045154_2

1429754-1430023

Orphan

I-F

Consensus_repeat	Method
GTTCACTGCCGCACAGGCAGCTTAGA	PILER-CR
GTTCACTGCCGCACAGGCAGCTTAGAAA	CRISPRCasFinder
GTTCACTGCCGCACAGGCAGCTTAGAAA	CRT

4 spacers

The CRISPR arrays of NZ_CP045154_2

>merge|NZ_CP045154|2|1429754-1430023|PILER-CR,CRISPRCasFinder,CRT
GTTCACTGCCGCACAGGCAGCTTAGAAACTGATACAATCATCCTATTTGTCCTATCCAGAAGTTCACTGCCGCACAGGCAGCTTAGAAAGACAAGAACCGAATCTTTCGCCGTGCCGTAAAGTTCACTGCCGCACAGGCAGCTTAGAAACCGAAATCATCAGATGTAATTAAGATTTTTGCTGTTCACTGCCGCACAGGCAGCTTAGAAAAGACTGATGCAAGATGGCGGTATGCGTACAGAGTTCACTGCCGCACAGGCAGCTTATAGA

>NZ_CP045154|2|1|1429754-1430021|PILER-CR
GTTCACTGCCGCACAGGCAGCTTAGA	AACTGATACAATCATCCTATTTGTCCTATCCAGAA
GTTCACTGCCGCACAGGCAGCTTAGA	AAGACAAGAACCGAATCTTTCGCCGTGCCGTAAA
GTTCACTGCCGCACAGGCAGCTTAGA	AACCGAAATCATCAGATGTAATTAAGATTTTTGCT
GTTCACTGCCGCACAGGCAGCTTAGA	AAAGACTGATGCAAGATGGCGGTATGCGTACAGA
GTTCACTGCCGCACAGGCAGCTTATA

>NZ_CP045154|2|2|1429754-1430023|CRISPRCasFinder
GTTCACTGCCGCACAGGCAGCTTAGAAA	CTGATACAATCATCCTATTTGTCCTATCCAGAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	GACAAGAACCGAATCTTTCGCCGTGCCGTAAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	CCGAAATCATCAGATGTAATTAAGATTTTTGCT
GTTCACTGCCGCACAGGCAGCTTAGAAA	AGACTGATGCAAGATGGCGGTATGCGTACAGA
GTTCACTGCCGCACAGGCAGCTTATAGA

>NZ_CP045154|2|1|1429754-1430023|CRT
GTTCACTGCCGCACAGGCAGCTTAGAAA	CTGATACAATCATCCTATTTGTCCTATCCAGAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	GACAAGAACCGAATCTTTCGCCGTGCCGTAAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	CCGAAATCATCAGATGTAATTAAGATTTTTGCT
GTTCACTGCCGCACAGGCAGCTTAGAAA	AGACTGATGCAAGATGGCGGTATGCGTACAGA
GTTCACTGCCGCACAGGCAGCTTATAGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045154.1\|WP_002227877.1\|1443002_1443923_+\|myo-inosose-2-dehydratase	unknown	unknown	gnl\|CDD\|275172
NZ_CP045154.1\|WP_002210302.1\|1438662_1439691_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224093
NZ_CP045154.1\|WP_002209745.1\|1418870_1419116_+\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|372675
NZ_CP045154.1\|WP_002227852.1\|1415454_1415706_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045154.1\|WP_002216002.1\|1417616_1418198_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045154.1\|WP_138921619.1\|1419328_1421641_-\|penicillin-binding-protein-1C	unknown	unknown	gnl\|CDD\|273954
NZ_CP045154.1\|WP_002210294.1\|1422459_1428438_-\|alpha-2-macroglobulin-family-protein	unknown	unknown	gnl\|CDD\|225248
NZ_CP045154.1\|WP_002223323.1\|1437103_1438651_+\|sugar-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224053
NZ_CP045154.1\|WP_002359655.1\|1432795_1434721_+\|3D-(3,5/4)-trihydroxycyclohexane-1,2-dione-acylhydrolase-(decyclizing)	unknown	unknown	gnl\|CDD\|226471
NZ_CP045154.1\|WP_002209749.1\|1415729_1416302_+\|Hcp-family-type-VI-secretion-system-effector	unknown	unknown	gnl\|CDD\|213799
NZ_CP045154.1\|WP_002210306.1\|1443932_1444748_+\|5-deoxy-glucuronate-isomerase	unknown	unknown	gnl\|CDD\|226241
NZ_CP045154.1\|WP_002210303.1\|1439714_1440848_+\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NZ_CP045154.1\|WP_002210296.1\|1430026_1430881_-\|MurR/RpiR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224651
NZ_CP045154.1\|WP_002210297.1\|1431234_1432761_+\|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|143404
NZ_CP045154.1\|WP_002210300.1\|1436125_1437055_+\|sugar-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380623
NZ_CP045154.1\|WP_002223316.1\|1428844_1429393_-\|DUF1440-domain-containing-protein	unknown	unknown	gnl\|CDD\|226008
NZ_CP045154.1\|WP_002210304.1\|1440879_1442850_+\|5-dehydro-2-deoxygluconokinase	unknown	unknown	gnl\|CDD\|378281
NZ_CP045154.1\|WP_002209748.1\|1416313_1416715_-\|DUF1240-domain-containing-protein	unknown	unknown	gnl\|CDD\|336520
NZ_CP045154.1\|WP_002209746.1\|1416947_1417349_-\|DUF1240-domain-containing-protein	unknown	unknown	gnl\|CDD\|336520
NZ_CP045154.1\|WP_002213775.1\|1421886_1422345_+\|IS200/IS605-like-element-IS1541B-family-transposase	unknown	unknown	gnl\|CDD\|224854

Protein	Function_ID	Function_description	E-value
NZ_CP045154.1\|WP_002210302.1\|1438662_1439691_+\|ABC-transporter-permease	gnl\|CDD\|224093	COG1172, AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism].	8.15893e-97
NZ_CP045154.1\|WP_002209745.1\|1418870_1419116_+\|transcriptional-regulator	gnl\|CDD\|372675	pfam13693, HTH_35, Winged helix-turn-helix DNA-binding.	5.27401e-36
NZ_CP045154.1\|WP_002227877.1\|1443002_1443923_+\|myo-inosose-2-dehydratase	gnl\|CDD\|275172	TIGR04379, myo-inositol_catabolism_protein, myo-inosose-2 dehydratase. Members of this family include the enzyme myo-inosose-2 dehydratase, product of the gene iolE, as found in inositol utilization cassettes in many species. [Energy metabolism, Sugars].	8.43662e-165
NZ_CP045154.1\|WP_138921619.1\|1419328_1421641_-\|penicillin-binding-protein-1C	gnl\|CDD\|273954	TIGR02073, Includes:_Penicillin-insensitive_transglycosylase, penicillin-binding protein 1C. This subfamily of the penicillin binding proteins includes the member from E. coli designated penicillin-binding protein 1C. Members have both transglycosylase and transpeptidase domains and are involved in forming cross-links in the late stages of peptidoglycan biosynthesis. All members of this subfamily are presumed to have the same basic function. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	0
NZ_CP045154.1\|WP_002210294.1\|1422459_1428438_-\|alpha-2-macroglobulin-family-protein	gnl\|CDD\|225248	COG2373, COG2373, Large extracellular alpha-helical protein [General function prediction only].	0
NZ_CP045154.1\|WP_002223323.1\|1437103_1438651_+\|sugar-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	0
NZ_CP045154.1\|WP_002359655.1\|1432795_1434721_+\|3D-(3,5/4)-trihydroxycyclohexane-1,2-dione-acylhydrolase-(decyclizing)	gnl\|CDD\|226471	COG3962, COG3962, Acetolactate synthase [Amino acid transport and metabolism].	0
NZ_CP045154.1\|WP_002209749.1\|1415729_1416302_+\|Hcp-family-type-VI-secretion-system-effector	gnl\|CDD\|213799	TIGR03344, VI_effect_Hcp1, type VI secretion system effector, Hcp1 family. This family includes Hcp1 (hemolysin coregulated protein 1), an exported, homohexameric ring-forming virulence protein from Pseudomonas aeruginosa. Hcp1 lacks a conventional signal sequence and is instead exported by means of the type VI secretion system, encoded by a pathogenicity cluster of a class previously designated IAHP (IcmF-associated homologous protein). Homologs of Hcp1, in this protein family, are found in various bacteria of which most but not all are known pathogens. Pathogens may have many multiple members of this family, with three to ten in Erwinia carotovora, Yersinia pestis, uropathogenic Escherichia coli, and the insect pathogen Photorhabdus luminescens. [Cellular processes, Pathogenesis].	2.31704e-76
NZ_CP045154.1\|WP_002210306.1\|1443932_1444748_+\|5-deoxy-glucuronate-isomerase	gnl\|CDD\|226241	COG3718, IolB, Uncharacterized enzyme involved in inositol metabolism [Carbohydrate transport and metabolism].	3.14642e-169
NZ_CP045154.1\|WP_002210303.1\|1439714_1440848_+\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	2.07432e-69
NZ_CP045154.1\|WP_002210296.1\|1430026_1430881_-\|MurR/RpiR-family-transcriptional-regulator	gnl\|CDD\|224651	COG1737, RpiR, Transcriptional regulators [Transcription].	1.17523e-68
NZ_CP045154.1\|WP_002210297.1\|1431234_1432761_+\|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase	gnl\|CDD\|143404	cd07085, ALDH_F6_MMSDH, Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2. Methylmalonate semialdehyde dehydrogenase (MMSDH, EC=1.2.1.27) [acylating] from Bacillus subtilis is involved in valine metabolism and catalyses the NAD+- and CoA-dependent oxidation of methylmalonate semialdehyde into propionyl-CoA. Mitochondrial human MMSDH ALDH6A1 and Arabidopsis MMSDH ALDH6B2 are also present in this CD.	0
NZ_CP045154.1\|WP_002210300.1\|1436125_1437055_+\|sugar-ABC-transporter-substrate-binding-protein	gnl\|CDD\|380623	cd19968, PBP1_ABC_IbpA-like, periplasmic sugar-binding protein IbpA of an ABC transporter and similar proteins. The periplasmic binding protein (PBP) IbpA mediates the uptake of myo-inositol by an ABC transporter that consists of the PBP IbpA, the transmembrane permease IatP, and the ABC IatA. IbpA shares homology with a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein superfamily, which consists of two domains connected by a three-stranded hinge.	4.31227e-120
NZ_CP045154.1\|WP_002223316.1\|1428844_1429393_-\|DUF1440-domain-containing-protein	gnl\|CDD\|226008	COG3477, COG3477, Predicted periplasmic/secreted protein [Function unknown].	1.03166e-68
NZ_CP045154.1\|WP_002210304.1\|1440879_1442850_+\|5-dehydro-2-deoxygluconokinase	gnl\|CDD\|378281	pfam09863, DUF2090, Uncharacterized protein conserved in bacteria (DUF2090). This domain, found in various prokaryotic carbohydrate kinases, has no known function.	0
NZ_CP045154.1\|WP_002209748.1\|1416313_1416715_-\|DUF1240-domain-containing-protein	gnl\|CDD\|336520	pfam06836, DUF1240, Protein of unknown function (DUF1240). This family consists of a number of hypothetical putative membrane proteins which seem to be specific to Yersinia pestis. The function of this family is unknown.	7.32611e-43
NZ_CP045154.1\|WP_002209746.1\|1416947_1417349_-\|DUF1240-domain-containing-protein	gnl\|CDD\|336520	pfam06836, DUF1240, Protein of unknown function (DUF1240). This family consists of a number of hypothetical putative membrane proteins which seem to be specific to Yersinia pestis. The function of this family is unknown.	5.05571e-40
NZ_CP045154.1\|WP_002213775.1\|1421886_1422345_+\|IS200/IS605-like-element-IS1541B-family-transposase	gnl\|CDD\|224854	COG1943, COG1943, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.50747e-46

>NZ_CP045154.1|WP_002223316.1|1428844_1429393_-|DUF1440-domain-containing-protein
MSEKRVNLQVIAWATIIGGFVSSLVKSGTEVNMPPRVVGEISPPAANIDAWLGWLGINSHSMDYVYQGVTISGAVVLYHWLFSFVFAFVYVLLSAYWPKVRLWYSAAYGLSITVAIHGVLIPALGFRHPAYLAGETGWLWNLNGYELWSEIIGHLCWSASLEICLVAVLAFFSKPIKGIWAN
>NZ_CP045154.1|WP_002210294.1|1422459_1428438_-|alpha-2-macroglobulin-family-protein
MDLLRFLLISPFALIKGLYRLSAYLLRLVGRLLRPVVGNLNWRAPQWMTKTANGLHCAFNRSEQWVAKHPKGISAAIVLLMAAASAAFYGYHWYLNRPQPIEPAPMVYQETSIRVSAPRTVNYQAQKPEAQPLSLNFMHSAAPITAMGQVVDQGISLTPAIEGEWKWATERTLVFTPKKAWPMGANYQITIDTEKLLAPQIKLNQTELNFTTPAFAYQLEKAEYYQDPQEAQKRSTIFHVQFNAPVDVASFEKQILLGLVEGKSKSEKKLNFSVVYDEKKLNAWIHSQPLMPMDKGGSVHLSINKGVNASVAATPTTQAQNKWVSVPNLYSLAVNSINATLVESDNNNGERALIIAISDAVKDKEIKNAVKAWLLPQHNFQAKESAKTSTDFYPWDMDDIDDNLLQQSTPLALTLNEAEQEYQPIFSFKFDAPSYRTLLIEVNNSLTSVGGYKMPEKIYQIVRVPDYPKTLRFMSQGSLLSMQGDKQISVAARNMTGMKLDIKRVIPSQLQHIVSFKSSEYSSAHFNRLSDEYFTEHFQYQTALNNDNPGEINYQGVDLSRYLANNPSARRGVFLLTLSAWDPEKRDNQQHSEEDYDEDQEWVGDSRFVVITDLGIITKQSQDRSRDVFVQSIHSGLPAADAKVSVVAKNGVVLLSQITDSKGHVHFPALDAFKNERQPVMFLVEKEGDVSFLPTRATYDRNLDFSRFDIDGEETPSDPRTLSSYLFSDRGVYRPGDRFNIGLITRTANWATALDGVPLRAEIRDPRDTLMSTLPITLDSSGFNELSYTTGENSPTGEWNVYLYLVGKNNETSMLLGHTTVNVKEFEPDRLKVQLQLTPERQQGWVKPQELQANINVQNLFGTPAQERRVTSRLILRPMYPSFAPFPDYLFYENRHNSDGFETELEEQTTDLQGMATIPLDLKSYADATYQLQLLSEAFEAGGGRSVAATARVLVSPYDSLVGVKADGDLSYINRDAVRKLNIIAVDPSLNKIALPDLSLSLIEQKYISVLTKQDSGVYKYQSRLKEQLVSEQPLQISPTGTDFTLVTQQPGDFILVVKDSQGQVLNRISYTVAGNANLTRSLDRNTELKLKLNQAEYLQGEEIEIAINAPYAGSGLITIEKDKVYSWQWFHSDTTSSVQRIRIPPAMEGNGYINVQFVRDVNSDEIFMSPLSYGVMPFKISTKARQAAIELASPSVIKPGEVLPIKVTTDSPQRVVVFAVDEGILQVARYRLKDPLDYFFRKRELSVQSAQILDLILPEFSKLMALTSAPGGDAGEGLDLHLNPFKRKQDKPVAYWSGITEVNGETTFNYPIPDYFNGKIRVMAISATPDRIGKVQTSTTVRDNFILTPNVPAMVAPGDEFDVTVGVSNNLQGLKGKAVDITVRLTPPPQLEVVGEAQHSLSLAEKRETLVSFRLRARSALGDAPLVFDASYGSQSSRRTVSTSVRPAMPFRTQSVMGRMEGNKHTVTNLRQMFDNYAQRQATASHSPLVLTQGLARYLADYPYYSSEQIVSRSIPLIMQSKHPEMDSALNQNEVRDQLKNMLRILSSRQNSTGAIGLWHASPTPDPFVTPYVVQFLLEAKSAGYSLPNDILEGANNALRLLAARPYDDLYSLRLRAFAVYLLTLQGEITTNTLASVQSTLQQLYPDSWQTDLSAIYLASSYRLLKMDDEANKLLQPTWKQLGKAYSKAWWTQNYFDPLVQDATRLYLITRHFPEKVSSIPPQALENMVLALRDEHYTTYSSAMSILALESYTSQVAAQQDTPETLQIIEISKSKGIDPNVISTLNGLFVQGDFTGEAKAIQFNNYASAPAWYVVNQSGYDLQPPKDAISNGLEISRSYTDEQGKPVTQVTLGQKVNVHLKIRANAKQGQNNLAIVDLLPGGFEVVQQTAPEPEFYDNQDDQDEETGSGWQSPLMVSGSSWYPDYSDIREDRVIIYGSASTDVKEFIYQIKSTNTGRFVVPPAYGEAMYDRNVQALSVGKGHILVVPPEAK
>NZ_CP045154.1|WP_002213775.1|1421886_1422345_+|IS200/IS605-like-element-IS1541B-family-transposase
MRDEKSLAHTRWNCKYHIVFAPKYRRQVFYREKRRAIGSILRKLCEWKNVNILEAECCVDHIHMLLEIPPKMSVSGFMGYLKGKSSLMLYEQFGDLKFKYRNREFWCRGYYVDTVGKNTARIQEYIKHQLEEDKMGEQLSIPYPGSPFTGRK
>NZ_CP045154.1|WP_138921619.1|1419328_1421641_-|penicillin-binding-protein-1C
MALFLLALLVIGFRLWPHPPLSQGLPLSTAYYDRHGTLLRLSLANDDRYRLWTPLEEISPLVIQGIQLHEDRGFYYHPGVNPISLLRGFWQSYVQGGRQQGGSTLTMQLARMHWHLNTRSPTGKLRQIARAIQLELSYSKHDILEAYLNYAPYGRNIESIAAASLIYFDKKPQQLTLPEALTLAVLPQSPSYRIDPTTGVLGSALTQARNRLFVRWQQTYPTDSSQMALFQLPLSLRQPEKMPYIAPHFIEQIRRQNQQLANTQSQVDTTLDANLQQLVEKQVEAFIRRNNSRGIHNAAVLLLDTRDMGVRALVGSANYYDREIQGQVNGTNAKRSPGSTLKPFIYALGLEQGILHPMTILKDVPSSFGAYAPENFDHRFLGPVTATDALNFSRNIPAVYVASRLRQPTLYQFLRLSGVTNMASENHYGLSLVLGGGEITLQELARLYAMLANRGTLHPIQMVQTDKTLPSIRLLSEAASFITLDMLRQHRRPGDTLAQSPTSLPVYWKTGTSWGFRDAWSAGIFGPYVLIVWEGNFAGKGNSAFVGADAAAPLFFNIIDSIQANYPALREPKHPWPPQLKRVAICLASGNLPTPWCQQQGKTWFIPGKSPIKVDTVYRPVVIDINSGQAACLPYDRSQTRTEVFEFWPSDLANVFAQAGLPKRQPPDRSHCKEGNTLASGNAPRITSPLRNTTYTLRQSQQGRDQIVFSATLDADSTTTYWFVDDIYLGSSTSKKSIDWHPTRSGQYRIRAIDDHGRADSRLIRVEKVD
>NZ_CP045154.1|WP_002209745.1|1418870_1419116_+|transcriptional-regulator
MDKQDWHPADILAGLKKRGTTMAALSRKSGLASSTLANTLLRPWPKGERLIAEVLELHPAEIWPSRYLKPKKSPAESVNPG
>NZ_CP045154.1|WP_002216002.1|1417616_1418198_-|hypothetical-protein
MKYNSVLKTFVDDDYRLEDHLDFKKQHADIRYQKLHKQLNEMSDENMHALLTIEEGEYFLKTLCNPNPHQSWKDAIFSCTDPTSVFFGSLVESLSVSRIVFEIRGFGVTATEYVGKNGSSYIKLSGYAGIRKYLDATRYLIDNPKILDIGIGTQGIENGIVRGARFCIVFSAAYRSVELLLKDEYGLADFLLI
>NZ_CP045154.1|WP_002209746.1|1416947_1417349_-|DUF1240-domain-containing-protein
MVKINRPLVGAFAILLFFLSSWGCWFSLSGYLAFFKLSDVIIFSWKVGFVIFAVPLLFYFSYLAFFSAIKNKPAIMNNKLANALAILAILGSIISLFSSAYISYSLTEYSYKSCPRSSWMSPNKYVKDIKLCP
>NZ_CP045154.1|WP_002209748.1|1416313_1416715_-|DUF1240-domain-containing-protein
MVKINRPLFGAFAVFLLFLSCWVSWFSLNGYWDFFKLSDVIIFSWKVGVMIFGAPVLFYFSYLAFYCAIKNKPAKVNNKLANTFAMLAMLGVVISFFSSVYIGYSLTEYGYKLCSRSSWMSPNEYVKDIKLCP
>NZ_CP045154.1|WP_002209749.1|1415729_1416302_+|Hcp-family-type-VI-secretion-system-effector
MSNLIYASVNGKKQGLISAGCSSLNSIGNRCQAGHEDQIQVLSLNHSISRQQNVAHHPVHFVKPIDKSSPLLGVAISENERINVVFYFYRVNSAGQLELYYEVKLTDASIVDITSVYPHSIDNNEMIPYEKIQLKYKSIAWDHKSAGTSGYSVWEDRVYSFLISSTLFQVCLNIFIFFNWLVYQNYFWEK
>NZ_CP045154.1|WP_002227852.1|1415454_1415706_+|hypothetical-protein
MMKNNKNINKDEFSDKLSQQIKEMINNSQLDSVEILSVVMESIFSLFSETEGHLAEMKFIDSAGEDYRFILRLEVPPILERQH
>NZ_CP045154.1|WP_002210296.1|1430026_1430881_-|MurR/RpiR-family-transcriptional-regulator
MTTASNLSELQQQIRDRYDNLSKRLQQVSRYVLDNTNSVAFDTVAVIAERADVPPSTLIRFANAFDFSGFNEMKQLFRMNLVEETASYTDRARLFRAMESEAVPETPLGILQEFARSNAQALQQLAARTEPEMLQRAVELLAQADTIYVVGLRRSFSVAAYLTYALSHLECRPVQLHGLGGMLREQVNSIKARDIVVSISFSPYAEETVMVSEIAASAGARQIVITDSQISPLATFSDLCFVVKEAQVDAFRSQSATLCLVQSLVVALAYQQEAQAGAALAHRQ
>NZ_CP045154.1|WP_002210297.1|1431234_1432761_+|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase
METVANFINGKCVFSCGNSVTSGSPRAQAIFNSATGEPIRQVMMSTAQETEQAITAAQQAFASWSRQAPLKRARVMFRFKSLLEQHLDALAQLISEEHGKVYSDAVGELTRGLEVVEFACGIPHLQKGEHSANVGTGVDNHSLMQPLGVCVGITPFNFPAMVPMWMFPIALATGNTFVLKPSEKDPSLAVRLAQLLTEAGLPDGVFNVVQGDKTAVDVLLTDPRVQAVSFVGSTPIAEYIYQTASAHGKRCQALGGAKNHCILMPDADMDMAASAIMGAAYGAAGERCMALSVVLAVGDETADNLCARLEQQISTLRVGPGLAQEPENDMGPLISAPHRAKVLGYIDSGVAQKATLRIDGRGLKVAGHEQGYFVGPTLFDHVTPAMTIYQEEIFGPVLSVVRIADYRSAVDLINRHEYGNGTAIFTRDGGTARRFCEEVQVGMVGVNVPIPVPVAFHSFGGWKRSIFGPLNVHGNDGVRFYTRMKTITARWPEAQHDQGAAFSMPTLG
>NZ_CP045154.1|WP_002359655.1|1432795_1434721_+|3D-(3,5/4)-trihydroxycyclohexane-1,2-dione-acylhydrolase-(decyclizing)
MKTVRMTMAQALVRFLNQQYVAIDGQEVAFVHGVMTIFGHGNVLGIGQALEENPGHLQVHQGCNEQGMAHMAIGFAKQYRRQRIYAVSSSIGPGAANMVTAAATATANRIPLLLLPGDIYASRQPDPVLQQIEQYHDLSISTNDCFRPVSRYWDRINRPEQLMSAMLSAMRVLTDPADTGAVTLCLPQDVQGEAWDYPASFFERRVHRIERRPPDTRRLSDALSLIARKRRPLVVCGGGVRYSGAHEAFRAFVENAQLPFTETQAGKGALPSDHPLNLGGIGVTGGLAANRLAPQADLVIGIGTRLTDFTTGSKALFSHPEVAFLLLNVAEFDALKLDATALIADARVGLEALTEGLAGYRTAWQGDIIEAKAAWCDECQRLWSRTWRPDEVPEVAGHLDDSLQEYAEVLNTTLTQTRVLGLINQHIEDDAIVVGAAGSLPGDLQRLWQVKTADTYHLEYGYSCMGYEIAAAIGAKIAMPHQPVYAMVGDGSYMMLHSELHTAVQEGLKITVLLFDNAGFGCINNLQMGHGMGSFCTESRHRNHESGQLNGPLICVDFAQNAESYGCRAWRVHDEPSLLAALAASRDHPGPVLLDIKVLPKSMTHDYASWWRTGDAQIARSPAVQQAAERTQMKVKRARQY
>NZ_CP045154.1|WP_002210300.1|1436125_1437055_+|sugar-ABC-transporter-substrate-binding-protein
MKKLILAALIVFTSGVAFAENEQIVFSTPNLAMPFEVHMQRTAVKTAKALGVKLQVLDGQGSSPKQVADLENAITRGAQGFIVSPNDINAISSAVEEIQQAKLPVVTLDRSVESEKKVPHFGANNYKGGEAIANYVKSMFPNGAEIVLLTGQPGSSSNIERTKGIRDSLKTGGDKYRIVVDQTGNWMRSEGMRIIESVLPSLPKPPQVILSANDDMALGAIEALQSHGMKPGEIMVTGFDAVPEALARVREGWMAVTADQRPGYAVTTAMNQLVANIRDQKAITGADFLPTMITKENLDQAERVSEAGK
>NZ_CP045154.1|WP_002223323.1|1437103_1438651_+|sugar-ABC-transporter-ATP-binding-protein
MSQPLLKITDMAKSFSGVWALSNVQLTLEQGEIHALLGENGAGKSTLLKALSGAQPQTHGEIWFNGEMLALDDSPVERQNKGIITIYQEVNLLPNMTVAENMFLGREPRRRQVFVDEKAVNQEAQAILDYLQLNVSPTTAVARLSIAQQQMVEIARALTLNAKLIVMDEPSAALSDSEVESLHRVVRELKGRGVSIIYVTHRLHEVFQLCDRFTVFQDGRYTGSDEVAGTNVEKIIRLMVGRDVVFNRRPASETHHQDQPIRLSVQGLCREKPPLDPHGVALKDISFHVHAGEVLGIAGLVGAGRTEVARCLFGAGAFTSGNFEIDGVPYQPRDPMFALEQGIALVPEDRKKEGAVQGLSIRDNLTLSSLAGLLQWRFFVNTRKEDQLIETYRLALQIKMVNSEQAVRKLSGGNQQKVILARCMALNPRILIVDEPTRGIDVGTKSEVHQVLFDMAKQGVAVIVISSDLPEVLAVSDRIITLSEGRVTGEIHGDDASEERLMTMMTINHNALNAA
>NZ_CP045154.1|WP_002210302.1|1438662_1439691_+|ABC-transporter-permease
MLQPLSKPQASVKSAMRFDPITFFERFGVLIFMFLLLIFFQLQNSNFLSERNIFNILTEVSIYGIMAVGMTFVILTAGIDLSVGSILAVSAMTAAYVIKGDNFTTIDPNAWGGMSWLIGLSICLAMGTLIGFLQGLGVTRLRLPPFIVTLGGMTIWRGLTLVINDGAPIAGFDAGYRWWGRGDLLGISIPIWIFAIVAIAGYLALHKTRWGRFVYAIGGNPEAARLAGVNVKRVLVSVYVVIGCLAGLAGFILSARLGSAEAVAGISFELRVIASVVIGGTSLMGGYGRIGGTIIGSIIMGILINGLVLMNVSAYYQQIITGLIIVLAVAFDTYAKNRRGAL
>NZ_CP045154.1|WP_002210303.1|1439714_1440848_+|Gfo/Idh/MocA-family-oxidoreductase
MKEVRIGLIGTGYIGKAHAIAYAQAPTVFELRGKLVREMVAEVSPALAAQRAQAFGFNRFTCDWRELVADPAIDVVDICSPNYLHKEMALAAIHHGKHVYAEKPLALNARDASEMAAAATRAGVKTLVGFNYIKNPSAKLAKEIIERGEIGEVIHFYGTHNEDYMADPNTPIHWHCLHATAGLGALGDLAAHIVSMAQYLVGEITQVCGDLKTVVVTRPASVGSSARVAVENEDQAHAMVRFVNGAQGVIEASRVACGRKMGLSYMITGTQGAISFTQERMAELKLYLHNDPVNRQGFRTLLVGPAHPEYAAFCMAAGHGIGFNDQKTVEVRDLIDGIAMDTPLWPDFAEGWKVSRILDAIALSHQDSRWVNVTDIV
>NZ_CP045154.1|WP_002210304.1|1440879_1442850_+|5-dehydro-2-deoxygluconokinase
MSVEKQFSVSAEKTCNTENKCNTEKKFDVICMGRIAVDLYGQQIGARLEDVASFAKYLGGSSGNVAYGSARQGLRSSMLARVGDEHMGRFLREELHQVGCDTSHLTTDKKRLTALVLLSIKDRDTFPLIFYRDNCADMAITAQDFSEQYIASARSLAITGTHLSHPNTREAVLTALRYARRNGVRTVLDIDYRPVLWGLTSLGDGETRFIESHQVTAELLAVFNLFDVIVGTEEEFHIAGGSTNTLDALRGVREVSDAALVCKRGALGCSVYTEAIPQTLDEGLTVSGVRVKVLNVLGAGDAFMSGLLRGYLNDEGWPQACRYANACGALVVSRHGCAPAMPSKIELDNYLARADAVVRPDLDVHLNHLHRVTTRRRQWPELCVMAFDHRSQLEEMALQCGADLCHISTLKTLILQASREAVHTAGLQGKAGLLCDGTFGQDALNAITGAGWWIGRPIELPGSRPLAMEHGNIGSQLIGWPQEHIVKCLVFFHPEDAYSLRLEQEQKIIEVYRACCQSGHELLLEVILPAGMPRSDELYLRAISRFYNLGVYPDWWKLPPLASEGWAALNKLIERRDPHCRGVVILGLDASLEALRTGFNAAAGYPIVKGFAVGRTLFGDASLAWLKRDIDDTQLIARIRDNYLQLITLWRERGQK
>NZ_CP045154.1|WP_002227877.1|1443002_1443923_+|myo-inosose-2-dehydratase
MRKTEADRHTTAVQLGINPLTWTNDDLPSLGAETSLETCLSEGKEAGFAGFELGNKFSREAGVLGPILEHHQLKLVSGWYSGRLLERSVEEEIVAVRSHLALLRELGAKVMVFAEVSGCIHGEQQTPVHLRPRFPPARWAEYGAKLTAFARYTQALGVQIAYHHHMGTVIESAQDIDNLMIHTGEEVGLLLDTGHLTFAGADPLAVAQRWIARINHVHCKDVRTSVLADVKNRKTSFLDAVLSGVFTVPGDGGVDYPPIMALLKQHGYQGWLVVEAEQDPNVAHPMTYARMGYHNLSRLAHNAGLI
>NZ_CP045154.1|WP_002210306.1|1443932_1444748_+|5-deoxy-glucuronate-isomerase
MSRLLSRRQAPDERGLTQRITPAQAGWGYVGFEVYELNEGQPLTLTAVPDERCLVLIAGRASISTPSAQFPNIGDRMSPFERHKPWAVYVTPGEAVQVQAITPLELAVCSAPGKGTYPTRLISPEDIGAEARGKGHNQRYVHNILPEDHPADSLLVVEVYTNEGASSSYPSHKHDTDNPPHETYLEETYYHRLNPEQGFCMQRVYTDDRSLDECMAVYNREVVMVPRGYHPVATMAGYDSYYLNVMAGPVRKWIFSWENDHVWINHNYPIT

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Crispr_ID: NZ_CP045154_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045154_3

1986282-1986403

Orphan

Consensus_repeat	Method
CTTAATGCCAATATTAATCGACATAATCAATTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045154_3

>merge|NZ_CP045154|3|1986282-1986403|CRISPRCasFinder
CTTAATGCCAATATTAATCGACATAATCAATTGTAGTGGAGGGGGAGGATTGAGTTTTTTCCAAAAAAACATATTGCAGTATTAAATCTCTTAATGCCAATATTAATCGATATAATCAATTG

>NZ_CP045154|3|3|1986282-1986403|CRISPRCasFinder
CTTAATGCCAATATTAATCGACATAATCAATTG	TAGTGGAGGGGGAGGATTGAGTTTTTTCCAAAAAAACATATTGCAGTATTAAATCT
CTTAATGCCAATATTAATCGATATAATCAATTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045154.1\|WP_002221095.1\|1972468_1974523_+\|DNA-helicase-IV	unknown	unknown	gnl\|CDD\|182930
NZ_CP045154.1\|WP_002213039.1\|1982711_1985129_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366708
NZ_CP045154.1\|WP_002213058.1\|1975226_1975907_-\|DUF2057-family-protein	unknown	unknown	gnl\|CDD\|179619
NZ_CP045154.1\|WP_002213026.1\|1991024_1991744_+\|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl\|CDD\|223955
NZ_CP045154.1\|WP_002213056.1\|1976222_1976639_+\|CoA-binding-protein	unknown	unknown	gnl\|CDD\|224745
NZ_CP045154.1\|WP_002213036.1\|1986759_1986978_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045154.1\|WP_002213017.1\|1993853_1994102_+\|acyl-carrier-protein	unknown	unknown	gnl\|CDD\|180851
NZ_CP045154.1\|WP_002213060.1\|1974583_1975048_-\|methylglyoxal-synthase	unknown	unknown	gnl\|CDD\|179969
NZ_CP045154.1\|WP_002213024.1\|1992500_1993289_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|212491
NZ_CP045154.1\|WP_002213030.1\|1989040_1989778_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187594
NZ_CP045154.1\|WP_002213052.1\|1977125_1978316_-\|23S-rRNA-(cytosine(1962)-C(5))-methyltransferase-RlmI	unknown	unknown	gnl\|CDD\|185082
NZ_CP045154.1\|WP_002213034.1\|1987241_1987766_+\|beta-hydroxyacyl-ACP-dehydratase	unknown	unknown	gnl\|CDD\|223835
NZ_CP045154.1\|WP_002213032.1\|1987755_1989039_+\|beta-ketoacyl-[acyl-carrier-protein]-synthase-family-protein	unknown	unknown	gnl\|CDD\|238430
NZ_CP045154.1\|WP_002213038.1\|1985282_1986029_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|180440
NZ_CP045154.1\|WP_162006469.1\|1993375_1993816_+\|lipocalin-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|372819
NZ_CP045154.1\|WP_002213046.1\|1978739_1979069_-\|sulfurtransferase-TusE	unknown	unknown	gnl\|CDD\|225472
NZ_CP045154.1\|WP_002213049.1\|1978409_1978688_+\|acylphosphatase	unknown	unknown	gnl\|CDD\|184675
NZ_CP045154.1\|WP_002213028.1\|1989793_1991032_+\|hydroxymethylglutaryl-CoA-synthase-family-protein	unknown	unknown	gnl\|CDD\|225959
NZ_CP045154.1\|WP_002213025.1\|1991745_1992498_+\|enoyl-CoA-hydratase	unknown	unknown	gnl\|CDD\|235936
NZ_CP045154.1\|WP_002213054.1\|1976747_1977065_-\|heat-shock-protein-HspQ	unknown	unknown	gnl\|CDD\|184526

Protein	Function_ID	Function_description	E-value
NZ_CP045154.1\|WP_002221095.1\|1972468_1974523_+\|DNA-helicase-IV	gnl\|CDD\|182930	PRK11054, helD, DNA helicase IV; Provisional.	0
NZ_CP045154.1\|WP_002213039.1\|1982711_1985129_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366708	pfam01565, FAD_binding_4, FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidizes the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan.	1.41205e-31
NZ_CP045154.1\|WP_002213058.1\|1975226_1975907_-\|DUF2057-family-protein	gnl\|CDD\|179619	PRK03641, PRK03641, DUF2057 family protein.	4.09411e-122
NZ_CP045154.1\|WP_002213026.1\|1991024_1991744_+\|enoyl-CoA-hydratase/isomerase-family-protein	gnl\|CDD\|223955	COG1024, CaiD, Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism].	1.17502e-35
NZ_CP045154.1\|WP_002213056.1\|1976222_1976639_+\|CoA-binding-protein	gnl\|CDD\|224745	COG1832, COG1832, Predicted CoA-binding protein [General function prediction only].	1.53332e-71
NZ_CP045154.1\|WP_002213030.1\|1989040_1989778_+\|SDR-family-oxidoreductase	gnl\|CDD\|187594	cd05333, BKR_SDR_c, beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs. This subgroup includes the Escherichai coli K12 BKR, FabG. BKR catalyzes the NADPH-dependent reduction of ACP in the first reductive step of de novo fatty acid synthesis (FAS). FAS consists of four elongation steps, which are repeated to extend the fatty acid chain through the addition of two-carbo units from malonyl acyl-carrier protein (ACP): condensation, reduction, dehydration, and a final reduction. Type II FAS, typical of plants and many bacteria, maintains these activities on discrete polypeptides, while type I FAS utilizes one or two multifunctional polypeptides. BKR resembles enoyl reductase, which catalyzes the second reduction step in FAS. SDRs are a functionally diverse family of oxidoreductases that have a single domain with structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet) NAD(P)(H) binding region and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRS are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes have a 3-glycine N-terminal NAD(P)(H) binding pattern: TGxxxGxG in classical SDRs. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P) binding motif and an altered active site motif (YXXXN). Fungal type type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P) binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction. A critical catalytic Tyr residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering), is often found in a conserved YXXXK pattern. In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) or additional Ser, contributing to the active site. Substrates for these enzymes include sugars, steroids, alcohols, and aromatic compounds. The standard reaction mechanism is a proton relay involving the conserved Tyr-151 and Lys-155, and well as Asn-111 (or Ser). Some SDR family members, including 17 beta-hydroxysteroid dehydrogenase contain an additional helix-turn-helix motif that is not generally found among SDRs.	2.26541e-68
NZ_CP045154.1\|WP_002213017.1\|1993853_1994102_+\|acyl-carrier-protein	gnl\|CDD\|180851	PRK07117, PRK07117, acyl carrier protein; Validated.	4.77778e-09
NZ_CP045154.1\|WP_002213060.1\|1974583_1975048_-\|methylglyoxal-synthase	gnl\|CDD\|179969	PRK05234, mgsA, methylglyoxal synthase; Validated.	2.55286e-93
NZ_CP045154.1\|WP_002213024.1\|1992500_1993289_+\|SDR-family-oxidoreductase	gnl\|CDD\|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	5.49415e-40
NZ_CP045154.1\|WP_002213052.1\|1977125_1978316_-\|23S-rRNA-(cytosine(1962)-C(5))-methyltransferase-RlmI	gnl\|CDD\|185082	PRK15128, PRK15128, 23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI.	0
NZ_CP045154.1\|WP_002213034.1\|1987241_1987766_+\|beta-hydroxyacyl-ACP-dehydratase	gnl\|CDD\|223835	COG0764, FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases [Lipid metabolism].	1.09929e-42
NZ_CP045154.1\|WP_002213032.1\|1987755_1989039_+\|beta-ketoacyl-[acyl-carrier-protein]-synthase-family-protein	gnl\|CDD\|238430	cd00834, KAS_I_II, Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP.	2.93328e-136
NZ_CP045154.1\|WP_002213038.1\|1985282_1986029_-\|SDR-family-oxidoreductase	gnl\|CDD\|180440	PRK06172, PRK06172, SDR family oxidoreductase.	1.01866e-70
NZ_CP045154.1\|WP_162006469.1\|1993375_1993816_+\|lipocalin-like-domain-containing-protein	gnl\|CDD\|372819	pfam13924, Lipocalin_5, Lipocalin-like domain. This family includes domains distantly related to lipocalins. However, they do contain the important GXW motif in the first strand. The protein in this family include aln5, which is involved in biosynthesis of alnumycin. The family also includes the ZFK protein from Trypanosoma brucei which is a protein kinase. This domain is at the C-terminus of that protein. The domain is also found as the C-terminal domain in StiJ a protein involved in producing stigmatellin. This domain has been assumed to catalyze a final cyclisation reaction.	7.96303e-46
NZ_CP045154.1\|WP_002213046.1\|1978739_1979069_-\|sulfurtransferase-TusE	gnl\|CDD\|225472	COG2920, DsrC, Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism].	2.4785e-71
NZ_CP045154.1\|WP_002213049.1\|1978409_1978688_+\|acylphosphatase	gnl\|CDD\|184675	PRK14426, PRK14426, acylphosphatase; Provisional.	1.02172e-54
NZ_CP045154.1\|WP_002213028.1\|1989793_1991032_+\|hydroxymethylglutaryl-CoA-synthase-family-protein	gnl\|CDD\|225959	COG3425, PksG, 3-hydroxy-3-methylglutaryl CoA synthase [Lipid metabolism].	1.57028e-141
NZ_CP045154.1\|WP_002213025.1\|1991745_1992498_+\|enoyl-CoA-hydratase	gnl\|CDD\|235936	PRK07110, PRK07110, polyketide biosynthesis enoyl-CoA hydratase; Validated.	2.57932e-133
NZ_CP045154.1\|WP_002213054.1\|1976747_1977065_-\|heat-shock-protein-HspQ	gnl\|CDD\|184526	PRK14129, PRK14129, heat shock protein HspQ; Provisional.	3.64231e-72

>NZ_CP045154.1|WP_002213038.1|1985282_1986029_-|SDR-family-oxidoreductase
MKKTILITGALSGIGNTATKLFSEMGYNVVFSGRRPEEGRVILDDLKRINKDVLYVNADMNSESDIKHLIEMTLERFGSLDVAVNCAGTVGETAEIQAVTQDNFHLVFNTNVLGTLLAMKYQIPVMVERGKGSIINISSIAGLVGLPSTGIYVASKHAIEGLTKTAALEVATTGVRINSISPGPVEGKMFDRFLGHDENNKKAFIEMMPNKRFTTQEEVAHTIVFLAEDNVTAITGQTITIDGGYTAQ
>NZ_CP045154.1|WP_002213039.1|1982711_1985129_-|GNAT-family-N-acetyltransferase
MTTTLDIINSAKDLDPAEYRAFFLQSKAPLFYDLRFLIAAEQSPLLNVSKIFYLLARDEGRLIALVPLYLQEFRSADPLGLLISSAKLSIESEERGLFSHIIHCTDTTIPTLSHDPSLYARIFDAITAIAQAELARYFCFLNVQDGVLLREAQRNGLNINYMVDKFSIELDAFPDFDSFAQALPKYRRYEMVRQLRIFNRSDAKVRILAPPFDNEIEKLARLYYLTTQRLGTPYYWPESQLAVFCRLCGDLVRLIVVEQNGQIVSGFICFEEDGALHFWSAGMDDESSDFSPYTLGVSAVYRYAFEKGINLIECGRLNSHIKTRLGFKPKRLYSIVSQDLGIPAATQTSLSQLKLASQLDGEVRLASHPAFDEWYLTSVWNGRGPTRRPAGIVRAATEADVIRTIVFAKERGMEVSVRGSGHNYVGCFLRVDTLMLDISGLKGLDIDSRHKRAIVESGVSSGQLCHALAAKGLAFPTGHVKEVGISGFLLGGGLGINCSQWGGMSVFNVQALDIVTADGHLRHVSETQEPDLFWAARGAGPCSFFVVTRFYLSCYSLPRVITNSLYTLPFTYLHDLLARLEDASPPTNLQVMVSVSPPTSGDTPAVLLNILAFTDSPQEAQALCESFETRLELPLTALAINQPSNFETIYEQFSSMVVSKRFYADNILTDNTQELVSILSRYLSDAPSRGALTTIFWRGVTTYPQAAFSAHGKFFVSTYAQWDDAKDDSVNKYWLKRMYDELQEIARSRYINEYDLETRAGETSKCFAAENWERLQRLRLEYDPDGVFVDVQQLEEHGDQPGANN
>NZ_CP045154.1|WP_002213046.1|1978739_1979069_-|sulfurtransferase-TusE
MLEFEGRIIDTDAQGYLKNSTDWSEALAPVLAEQEGITLTEPHWEVVRFVRAFYQEFNTSPAIRMLVKAMAQKYGEEKGNSRYLYRLFPKGPAKQATKIAGLPKPVKCI
>NZ_CP045154.1|WP_002213049.1|1978409_1978688_+|acylphosphatase
MSKIYIVAYVYGVVQGVGFRYSTQRQAQQLGVTGYAKNCDDGSVEVVASGNPQAVERLMEWIRQGGPRGARVDRLLTEPYPPTPFETFSIRY
>NZ_CP045154.1|WP_002213052.1|1977125_1978316_-|23S-rRNA-(cytosine(1962)-C(5))-methyltransferase-RlmI
MTVRLILAKGREKSLLRRHPWIFSGAVQRLEGDALSGETIDILDSQGKWLARAAYSPESQILARVWTFQQDEVIDCAFFIRRLQQAQNWRDWLAQRDGLNGYRLIAGESDGLPGITIDRFQNFLVLQLLSAGAEYQRETLVSALQHCYPECSIYDRSDVSVRKKEGLPLTQGLICGEMPPALLPISENGMQLFVDIQQGHKTGFYLDQRDSRLAARNYANGRRVLNCFSYTGAFAVAALMGNCQQVISVDTSQSVLDIAKQNIELNQLDLSKTEFVRDDVFQLLRSYRAQGEKFDLIIMDPPKFVENKSQLASACRGYKDINMLAIQLLRPGGILLSFSCSGLMPVDLFQKILADAALDAGHDIQFIEQFRQAADHPVIAAYPEGLYLKGFACRVM
>NZ_CP045154.1|WP_002213054.1|1976747_1977065_-|heat-shock-protein-HspQ
MIASKFGIGQQVRHSLHGYLGVVIDIDPEYSLAPPEPDEVANNKTLRSSPWYHVVIEDDDGQPVHTYLAEAQLTYEDVDAHPEQPSLDELAASIRHQLQAPHLRN
>NZ_CP045154.1|WP_002213056.1|1976222_1976639_+|CoA-binding-protein
MHDKDIADILKKVKTIALVGASDIPSRPSYRVMAYLLQQGYQVTPVNPKLAGELLLGQLVYAELADIPHAIDMVDVFRNSDAAYCIAQDAIAIGAKVLWLQIGVINEQAAILATDAGLQVVMDRCPKIELPRLGLEKG
>NZ_CP045154.1|WP_002213058.1|1975226_1975907_-|DUF2057-family-protein
MKLGLVAGMLAVCFSFSSVAMTLKLTPEIDLLVVDGKNMSGSLLKGADSLELNSGMHQILFKVIKPLPTDPLVLYSSPPLIVVFNAHNTRSVAIKLPVINTLRDGHQFSKNPLYQLIGDNGHPLSVRHDVLRQDHLNNSTTLETVMAAYNVGKYNASVPAFAAIPPSPVSAVPGTTIPVAGVNTPHKTASLQGENVTEQMLQYWFLQANPETQKRFLIWAKKQPIH
>NZ_CP045154.1|WP_002213060.1|1974583_1975048_-|methylglyoxal-synthase
MELTTRTIAARKHIALVSHDHCKKSLLAWVMENRDLLAQHELYATGTTGNLVQKATGIDVHCLLSGPMGGDQEVGALISEKKIDILIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNRSTADFLIGSTLFSSEVTIAIPDYDRYMQQRLDLK
>NZ_CP045154.1|WP_002221095.1|1972468_1974523_+|DNA-helicase-IV
MELKATSFGKHLSQHPYNRVRLLNAGIEVCGDKHQYLIPFNQLVSIQCKRGIVWGELEFELPQQKVVRLHGTEWQETQHFYHYLLGVWQQWSEEMSQVCAEVLHKQVESIKRIEQQDKWFKRSELGQIQVMIREAFSALPMPVERLAAFESCRADYECCLRWLQQGRHSVERCNQQWTARMLEEYQDFFQNVETSPLNASQSRAVVNGEDSVLVLAGAGSGKTSVLVARAGWLLRRNEALPEQILLLAFGRQAADEMNSRIKQRLGVDSIQAKTFHALALHIIQQGSRKTPVISKLESDSQARRALLIQHWQQQCSEKKAQAKGWREWLTDELEWDVADGDFWQDKRLAARLASRLERWVGLMRMYGGSQAEMIEQANDEVRDLFQKRIRLMAPLLKAWKTALKDEGAVDFSGLIHQAVNLLEKGRFVSPWKHVLVDEFQDISPQRAMLLAALRKQNKQTCLFAVGDDWQAIYRFSGAELSLTTAFSEHFGEGAECALDTTYRFNDRIGDIANRFIQQNPYQLKKPLNSLSKGNKKSVMILPDEQLEALLDKLSGFVKDGERILILARYHHLRPEVLQKAATRWPKLTIDFMTIHASKGQQADYVIIVGLHEGNDGFPAAARESVLEDVLLPPPEDFPDAEERRLLYVAITRAKHQVWLLQDTARPSIFVSQLSELGALVQRKP
>NZ_CP045154.1|WP_002213036.1|1986759_1986978_+|hypothetical-protein
MYLLQQIELCPDQILHAWKISQNPQVSEVFEIEVVSSEEDAEEAVLFWKAYFSSLGETVIDGRHVGDTFSRF
>NZ_CP045154.1|WP_002213034.1|1987241_1987766_+|beta-hydroxyacyl-ACP-dehydratase
MKNTELNFLKTNFLFNQDITNELNTSFGQDIIKKMIPHREPFLMVDNVELINIECRLIKAIRRVDEKDPVFGGHFPNDPIYPGVLQQESMFQTALILMYFLLNETAIPPAEENIIHAVGTRVYDVFHLSAVRPGELMTIRCCITEYDTFLATAIVQITVNDQIVTVGKGEFHVF
>NZ_CP045154.1|WP_002213032.1|1987755_1989039_+|beta-ketoacyl-[acyl-carrier-protein]-synthase-family-protein
MSSDRIVITGVAINTPIGDTLDLVGNNLLSGKSAIGYWRNFDTSNIYSKIGGQIPEYDIEGKLHAFSNRIPDIVLSRAEKVFKQTTKGVQLSVLMAMEAWLDAGLFEHIIDPFDCGIICGGHNLSDKYLLDQQKIFSDEPEFIDAFSGLNSLDTDHSSSVAQVLNTKGFAYLVGGTCATGNIAIQTAINAIKVDKKQVVAVVCPMASFHPMMLHSLTILEAICYSQYQDTPTKASRPYDINRSGFLPSEGGAVLIFEQAEHAKNRGAKIYAELLGASVNSDANHLGDPSHEGQVRVIQDVLKKCNISPEQVDYVSAHATSTKLGDIVELKSIKRVFGSHAEKLIINAPKSLLGHTMWASGVVEAAIAIWQMRQGEFHQSHNIETLDPAVELNVCASGNVKKEVNIFLNNSFGMGGINSASLFSRYHG
>NZ_CP045154.1|WP_002213030.1|1989040_1989778_+|SDR-family-oxidoreductase
MNLFISGGASGIGRSVVIAALSKGWNVGFSYHNNKEGAQQLLDIAVAEFPRQLCRAYQLDVIDSGAVEYVGDRLLVDFSNIDAVVCNAGIDLPGNLVSMTDEDWALVLNTNLTGTFYLIRYFLPLFLANKYGRIVTLSSLAKDGSSGQAAYAASKAGLVGLTKTTAKEYGHFGITANVVVPGLINTEIIGDDIKGIKNFFAQYAPVGRLGSPSEVAEAILFLVAKESSYVNGAVFNVTGGIDWVY
>NZ_CP045154.1|WP_002213028.1|1989793_1991032_+|hydroxymethylglutaryl-CoA-synthase-family-protein
MNSIGIEKISIYPSSLALKLSELAQARGGDNKYIQESLMVIKRSLVPQWEDAVTLAVNSAKDMLNDQDRSDIGLFIIATESGLDQEKAISTWAHRYLGLPATCRVFELKSACHAGAAALKMAESWISSGLNRGKKVLLINVDISNNMICHGKMEYSLGAGAIALLISDNPVFAVIETGKSGIHTHEVTDVIRPLPWKEVAFDVEASLFSYMDGLENAFEEYCHQTPEARESTYFNYNLYHVPFPGISKEAHKVLLELQGLFGKEALATSFKQKVMPSLYYAQKIGATYCGSIFLSLFSLMVKAPEIKSGDRIGVYSYGSGSCAEYFSMQVGDQAVEIAQQQGAALDILLTQRKILDVAAYEQLENARSAQMQGKDYRLDGDNLQDWYTHHYSGSGLLILERIDNHLRRYRYA
>NZ_CP045154.1|WP_002213026.1|1991024_1991744_+|enoyl-CoA-hydratase/isomerase-family-protein
MHEYVTVPIKFSPDSLADFENRFISALNDERYKVIVLIGGPTYFSMGMDLTYISTHYDADFVSQFCHILKMVRNSHKPVLAKVEGNVIAGGLALLSVVDFILSSDSASFSLPEVTFGITPTIAMSCLLERIRPHHLKYFVWSSSVISAKQALKWGLIDQINTLENLDQDIQVISNKLSRIPKSAIRESKLLLAEQYSFEESLDLGSHLLVERLNDAQTIEKIRHYLEDIKLFNDEYADD
>NZ_CP045154.1|WP_002213025.1|1991745_1992498_+|enoyl-CoA-hydratase
MKKIYLRKSDEGIAFMHINDPVNKNAIDDEFCLQLHGIVDTIKQDKTIKVLILVGLPDIFCTGGTEAFLQSLITHYKTNIEHEYANHLKHFLNIPIPVIAAMEGSATGGGLVLGLYADILVAAEESRYGMSFMNMGFTPGMGSTAMSKEAFGYYTGFEMMVTGNYIRGSELKGKCCFNYILPRAMVMEKAIELATSIAEKPRHSLELLKKYMSIDRRKMLEETSTIEAFMHHIAFNQSNIEQQIQDNYTG
>NZ_CP045154.1|WP_002213024.1|1992500_1993289_+|SDR-family-oxidoreductase
MLNNLSEMTVLVTGGTKGIGRATVESFVKAGAKVYGTYFWGDNLDELENHFSQYLNRPVFLQADISDEEITTQLIEKIAQENKKIDILILNAAFAPQFKDTYKFRGLLDSIEHNSWPLITYIDCIKQHFGQYPGYVVAITSEGHRSCHITGYDYVAASKAVLETLTKYIGARENIIINCISPGVVDTEAFELVFGKKAQAFIRKFDPDFIVSPEAVGNVSVALCSGLMDAVRGQVITVDNGRMFTDNFTKWIDMIETNFIEK
>NZ_CP045154.1|WP_162006469.1|1993375_1993816_+|lipocalin-like-domain-containing-protein
MSNTNRNLFLGRWKLESCIGNSGGIHIYPIGREPFGMLIYTEQYMMVFISSVERTQFSTEDIRAIPSEQIVADFPKFETYCGHYIVNHDEKIVTHFIDNSKIPNQIGTQFRRYFSFEHEKLVLKSIDSLLLNDESWLFELVWNKQE
>NZ_CP045154.1|WP_002213017.1|1993853_1994102_+|acyl-carrier-protein
MDRDHIASIVKKHIVNSIDGAKEHEIDLQKSMADYGASSLDIVSVVSGVMRELKIKIPRTELKNIKSINGLIDLFVTSSSES

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Crispr_ID: NZ_CP045154_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045154_4

2112086-2112293

Orphan

I-F

Consensus_repeat	Method
GTTCACTGCCGCACAGGCAGCTTAGAAA	PILER-CR
GTTCACTGCCGCACAGGCAGCTTAGAAA	CRISPRCasFinder
GTTCACTGCCGCACAGGCAGCTTAGAAA	CRT

3 spacers

DEDDh

The CRISPR arrays of NZ_CP045154_4

>merge|NZ_CP045154|4|2112086-2112293|PILER-CR,CRISPRCasFinder,CRT
GTTCACTGCCGCACAGGCAGCTTAGAAAATGTTCGACGATTTATTTTATTTGTATTTCAGGTTCACTGCCGCACAGGCAGCTTAGAAAATTTATTAAAGATGCTGACAAAAAGAACTTAAGTTCACTGCCGCACAGGCAGCTTAGAAAGTCAACGCTTCACTCCCTGCGCGGGGTATAACGTTCACTGCCGCACAGGCAGCCCAATAA

>NZ_CP045154|4|2|2112086-2112233|PILER-CR
GTTCACTGCCGCACAGGCAGCTTAGAAA	ATGTTCGACGATTTATTTTATTTGTATTTCAG
GTTCACTGCCGCACAGGCAGCTTAGAAA	ATTTATTAAAGATGCTGACAAAAAGAACTTAA
GTTCACTGCCGCACAGGCAGCTTAGAAA

>NZ_CP045154|4|4|2112086-2112293|CRISPRCasFinder
GTTCACTGCCGCACAGGCAGCTTAGAAA	ATGTTCGACGATTTATTTTATTTGTATTTCAG
GTTCACTGCCGCACAGGCAGCTTAGAAA	ATTTATTAAAGATGCTGACAAAAAGAACTTAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	GTCAACGCTTCACTCCCTGCGCGGGGTATAAC
GTTCACTGCCGCACAGGCAGCCCAATAA

>NZ_CP045154|4|2|2112086-2112293|CRT
GTTCACTGCCGCACAGGCAGCTTAGAAA	ATGTTCGACGATTTATTTTATTTGTATTTCAG
GTTCACTGCCGCACAGGCAGCTTAGAAA	ATTTATTAAAGATGCTGACAAAAAGAACTTAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	GTCAACGCTTCACTCCCTGCGCGGGGTATAAC
GTTCACTGCCGCACAGGCAGCCCAATAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045154.1\|WP_002216393.1\|2123792_2124533_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187626
NZ_CP045154.1\|WP_002211917.1\|2125454_2126732_+\|L-fuconate-dehydratase	unknown	unknown	gnl\|CDD\|239440
NZ_CP045154.1\|WP_002216388.1\|2117452_2120605_-\|inverse-autotransporter-beta-barrel-domain-containing-protein	unknown	unknown	gnl\|CDD\|378762
NZ_CP045154.1\|WP_157131899.1\|2104441_2104732_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|374732
NZ_CP045154.1\|WP_002231208.1\|2103036_2103084_-\|his-operon-leader-peptide	unknown	unknown	unknown
NZ_CP045154.1\|WP_002211904.1\|2112327_2113758_-\|exodeoxyribonuclease-I	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|236979
NZ_CP045154.1\|WP_002209743.1\|2116281_2117490_+\|IS256-family-transposase	unknown	unknown	gnl\|CDD\|225865
NZ_CP045154.1\|WP_002211898.1\|2103459_2104287_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187576
NZ_CP045154.1\|WP_002217522.1\|2115593_2115911_+\|DUF496-family-protein	unknown	unknown	gnl\|CDD\|180070
NZ_CP045154.1\|WP_002216312.1\|2107938_2109030_+\|oxidoreductase	unknown	unknown	gnl\|CDD\|182570
NZ_CP045154.1\|WP_002211916.1\|2124580_2125423_+\|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
NZ_CP045154.1\|WP_002216310.1\|2106112_2106802_-\|sugar-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224053
NZ_CP045154.1\|WP_002211902.1\|2110199_2111591_+\|APC-family-permease	unknown	unknown	gnl\|CDD\|223605
NZ_CP045154.1\|WP_002211912.1\|2122942_2123365_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	unknown	unknown	gnl\|CDD\|225556
NZ_CP045154.1\|WP_002211905.1\|2114050_2115160_+\|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl\|CDD\|187547
NZ_CP045154.1\|WP_002211911.1\|2121629_2122934_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340877
NZ_CP045154.1\|WP_002211896.1\|2101854_2102754_-\|ATP-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|234781
NZ_CP045154.1\|WP_002211900.1\|2105120_2106116_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224093
NZ_CP045154.1\|WP_002213775.1\|2109315_2109774_+\|IS200/IS605-like-element-IS1541B-family-transposase	unknown	unknown	gnl\|CDD\|224854
NZ_CP045154.1\|WP_002216311.1\|2106759_2107653_-\|sugar-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224053

Protein	Function_ID	Function_description	E-value
NZ_CP045154.1\|WP_002216393.1\|2123792_2124533_+\|SDR-family-oxidoreductase	gnl\|CDD\|187626	cd05368, DHRS6_like_SDR_c, human DHRS6-like, classical (c) SDRs. Human DHRS6, and similar proteins. These proteins are classical SDRs, with a canonical active site tetrad and a close match to the typical Gly-rich NAD-binding motif. Human DHRS6 is a cytosolic type 2 (R)-hydroxybutyrate dehydrogenase, which catalyses the conversion of (R)-hydroxybutyrate to acetoacetate. Also included in this subgroup is Escherichia coli UcpA (upstream cys P). Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction. Note: removed : needed to make this chiodl smaller when drew final trees: rmeoved text form description: Other proteins in this subgroup include Thermoplasma acidophilum aldohexose dehydrogenase, which has high dehydrogenase activity against D-mannose, Bacillus subtilis BacC involved in the biosynthesis of the dipeptide bacilysin and its antibiotic moiety anticapsin, Sphingomonas paucimobilis strain B90 LinC, involved in the degradation of hexachlorocyclohexane isomers...... P).	1.05065e-117
NZ_CP045154.1\|WP_002211917.1\|2125454_2126732_+\|L-fuconate-dehydratase	gnl\|CDD\|239440	cd03324, rTSbeta_L-fuconate_dehydratase, Human rTS beta is encoded by the rTS gene which, through alternative RNA splicing, also encodes rTS alpha whose mRNA is complementary to thymidylate synthase mRNA. rTS beta expression is associated with the production of small molecules that appear to mediate the down-regulation of thymidylate synthase protein by a novel intercellular signaling mechanism. A member of this family, from Xanthomonas, has been characterized to be a L-fuconate dehydratase. rTS beta belongs to the enolase superfamily of enzymes, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion.	0
NZ_CP045154.1\|WP_002216388.1\|2117452_2120605_-\|inverse-autotransporter-beta-barrel-domain-containing-protein	gnl\|CDD\|378762	pfam11924, IAT_beta, Inverse autotransporter, beta-domain. This is a family of beta-barrel porin-like outer membrane proteins from enteropathogenic Gram-negative bacteria. Intimins and invasins are virulence factors produced by pathogenic Gram-negative bacteria. They carry C-terminal extracellular passenger domains that are involved in adhesion to host cells and N-terminal beta domains that are embedded in the outer membrane. This family represents the beta-barrel porin-like domain in the outer membrane that can be found in intimins, invasins and some inverse autotransporters.	1.47456e-126
NZ_CP045154.1\|WP_157131899.1\|2104441_2104732_-\|hypothetical-protein	gnl\|CDD\|374732	pfam16695, Tai4, Type VI secretion system (T6SS), amidase immunity protein. Tai4 is a new form of autoimmunity protein for a type VI secretion system, T6SS. T6SS has roles in interspecies interactions, as well as higher order host-infection, by injecting effector proteins into the periplasmic compartment of the recipient cells of closely related species. Pseudomonas aeruginosa produces at least three effector proteins to other cells and thus has three specific cognate immunity proteins to protect itself. Tae4, or type VI amidase effector 4, in Enterobacter cloacae has a cognate Tai4 or type VI amidase immunity 4 protein. The effector is Tae4, pfam14113.	4.0065e-14
NZ_CP045154.1\|WP_002211904.1\|2112327_2113758_-\|exodeoxyribonuclease-I	gnl\|CDD\|236979	PRK11779, sbcB, exonuclease I; Provisional.	0
NZ_CP045154.1\|WP_002209743.1\|2116281_2117490_+\|IS256-family-transposase	gnl\|CDD\|225865	COG3328, COG3328, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.39969e-152
NZ_CP045154.1\|WP_002211898.1\|2103459_2104287_+\|SDR-family-oxidoreductase	gnl\|CDD\|187576	cd05266, SDR_a4, atypical (a) SDRs, subgroup 4. Atypical SDRs in this subgroup are poorly defined, one member is identified as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is related to, but is different from, the archetypical SDRs, GXGXXG. This subgroup also lacks most of the characteristic active site residues of the SDRs; however, the upstream Ser is present at the usual place, and some potential catalytic residues are present in place of the usual YXXXK active site motif. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	2.54107e-68
NZ_CP045154.1\|WP_002217522.1\|2115593_2115911_+\|DUF496-family-protein	gnl\|CDD\|180070	PRK05423, PRK05423, DUF496 family protein.	5.26004e-59
NZ_CP045154.1\|WP_002216312.1\|2107938_2109030_+\|oxidoreductase	gnl\|CDD\|182570	PRK10586, PRK10586, putative oxidoreductase; Provisional.	0
NZ_CP045154.1\|WP_002211916.1\|2124580_2125423_+\|fumarylacetoacetate-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	8.96038e-107
NZ_CP045154.1\|WP_002216310.1\|2106112_2106802_-\|sugar-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	1.76633e-90
NZ_CP045154.1\|WP_002211902.1\|2110199_2111591_+\|APC-family-permease	gnl\|CDD\|223605	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism].	3.72025e-45
NZ_CP045154.1\|WP_002211912.1\|2122942_2123365_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	5.0494e-57
NZ_CP045154.1\|WP_002211905.1\|2114050_2115160_+\|NAD-dependent-epimerase/dehydratase-family-protein	gnl\|CDD\|187547	cd05236, FAR-N_SDR_e, fatty acyl CoA reductases (FARs), extended (e) SDRs. SDRs are Rossmann-fold NAD(P)H-binding proteins, many of which may function as fatty acyl CoA reductases (FAR), acting on medium and long chain fatty acids, and have been reported to be involved in diverse processes such as biosynthesis of insect pheromones, plant cuticular wax production, and mammalian wax biosynthesis. In Arabidopsis thaliana, proteins with this particular architecture have also been identified as the MALE STERILITY 2 (MS2) gene product, which is implicated in male gametogenesis. Mutations in MS2 inhibit the synthesis of exine (sporopollenin), rendering plants unable to reduce pollen wall fatty acids to corresponding alcohols. This N-terminal domain shares the catalytic triad (but not the upstream Asn) and characteristic NADP-binding motif of the extended SDR family. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.89947e-61
NZ_CP045154.1\|WP_002211911.1\|2121629_2122934_+\|MFS-transporter	gnl\|CDD\|340877	cd17319, MFS_ExuT_GudP_like, Hexuronate transporter, Glucarate transporter, and similar transporters of the Major Facilitator Superfamily. This family is composed of predominantly bacterial transporters for hexuronate (ExuT), glucarate (GudP), galactarate (GarP), and galactonate (DgoT). They mediate the uptake of these compounds into the cell. They belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.17308e-74
NZ_CP045154.1\|WP_002211896.1\|2101854_2102754_-\|ATP-phosphoribosyltransferase	gnl\|CDD\|234781	PRK00489, hisG, ATP phosphoribosyltransferase; Reviewed.	6.63843e-161
NZ_CP045154.1\|WP_002211900.1\|2105120_2106116_-\|ABC-transporter-permease	gnl\|CDD\|224093	COG1172, AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism].	1.22935e-72
NZ_CP045154.1\|WP_002213775.1\|2109315_2109774_+\|IS200/IS605-like-element-IS1541B-family-transposase	gnl\|CDD\|224854	COG1943, COG1943, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.50747e-46
NZ_CP045154.1\|WP_002216311.1\|2106759_2107653_-\|sugar-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	3.90601e-98

>NZ_CP045154.1|WP_002211902.1|2110199_2111591_+|APC-family-permease
MAHDATVAVGTNQTGTNNRVQLRKTLTLVQVVMMGLAYLQPMTIFDTFGIVSGLTDGHVATSYAIALIAVLFTAVSYGKLVKRFPSAGSAYTYAQKSISPNVGFMVGWSSLLDYLFMPMINILLAKIYLEAIFPGVPSWIFVGALVSLMTLFNLRGINIVANLNSVIVVVQVAIMVVFMGLLIHGVYQGEGAGTLVSARPFYSENAHLVPMITGATILCFSFLGFDGISSLSEETPNAGKVIPKAIFLTALIGGIIFIAVSYCLQLYFPDISRFTDPEASQPEIMLFVAGKFFQSVILCFSCVTVLASGMAAHAGVSRLLYVMGRDGVFPEKVFGYVHPKWRTPAINVLLVGGVALSAISFDLVTATALINFGALVAFTFVNLSVIAQFYVRERRNSTFKDHFNYLILPMIGAGTVGVLWVNLESSSMTLGLVWGAIGLSYMVWKTRAFRRALPQFTEEPAQL
>NZ_CP045154.1|WP_002213775.1|2109315_2109774_+|IS200/IS605-like-element-IS1541B-family-transposase
MRDEKSLAHTRWNCKYHIVFAPKYRRQVFYREKRRAIGSILRKLCEWKNVNILEAECCVDHIHMLLEIPPKMSVSGFMGYLKGKSSLMLYEQFGDLKFKYRNREFWCRGYYVDTVGKNTARIQEYIKHQLEEDKMGEQLSIPYPGSPFTGRK
>NZ_CP045154.1|WP_002216312.1|2107938_2109030_+|oxidoreductase
MSANAIRVQVGPANYFSFPGAIDKLSEFYPQAALDKALWIYGERALAAAQDYLPKAFHGPQAVRAKFSTHCSQSTVADLVSAAGGDRQVVIGIGGGAVLDTAKVVARQLGVPLVAIPTIAATCAAWTPLSVWYNEAGQALNFEIFNDANHLVLVEPRIMLHAPVEYLLAGIGDTLAKWYEAVVLSPQPETLSLTVRLGLQAALEIRNVLLKQSEAALQAVAQGELTQDFLDVVDAIIAGGGMVGGLGERYTRVAAAHAVHNGLTLLPQTEHFLHGTKVAYGILVQTALLGQDEVLRSLIVAFNQLGLPTHLAALDVDINDREAIDRVIGRILKPGESIHYLPIALNSEKVWAAIEQVEIAAQH
>NZ_CP045154.1|WP_002216311.1|2106759_2107653_-|sugar-ABC-transporter-ATP-binding-protein
MSSIPPSRLEMRNISISFSGFHALQEVDFTLEGGSTHALIGANGAGKSTLMAILSGAHNHYRGEIFIDGQPIDIHSPRQARQHGIHVVQQEVDVALIPTLSVAENIMLDELADRGHLFNWPQLYRQAEALLEQLELKLNVRQRLESCTLAEKQQVLLARALSHQCRFLILDEPTAPLDQEESARLFRVVRRLQSEGIGIVFISHRIHELREVCDQLTVLRDGRRVSHDTMEGMSGEQIVEKMLGHTLEDISPLGERQSAAKHGCRKHYCRKHCYRSAAYMISISCAISPSHYIRAKF
>NZ_CP045154.1|WP_002216310.1|2106112_2106802_-|sugar-ABC-transporter-ATP-binding-protein
MRDISLTLHQGEILGIAGLAGAGKTELCKALFGDTPSTLERGELSGKAWRPRSPDRSVAQGLALVPEERRKEGIFIDEGIPMNLSVAADDSFSRWSLFSRRQELSWAKELIERLGIRTSSPQQKLAHLSGGNQQKVAIGKWLRGDAQVLIFDEPTKGVDIKAKQDLFSLIDQLAQQGKGIIYASGEFSELVGLCDRICVLWDGRIVAELNAAEVDEETLLLFSTGGTPQ
>NZ_CP045154.1|WP_002211900.1|2105120_2106116_-|ABC-transporter-permease
MSKELPLPDVQPWRHQLFDFLYKWGMLLTVVALIALFGLASDNFLDPNNIINILRSIAIVTVIAIGVSISLSIGGFDLSVGSTASLANAVVVSLFVWYGFGTTGAIILTLLICTLVGLFNAFLIVVLKIPDMLATLASLFVIQGVAMTYSRGGSITQSMLLPSGDMAEGVIPEIFSALGQVPVIVLIMLAVTVVVQLYLSLTKHGRRMYAIGGNPQAARLAGIRTVRYRVLAYVLSAQLAALGGILLASRIGSSQVNAGSGYLMDAVAAAYIGFSLAGSGKPNAFGTLIGAIILGVLQNGLVMLSVPYYAMDIIKGLVLAMALALTYIQKR
>NZ_CP045154.1|WP_157131899.1|2104441_2104732_-|hypothetical-protein
MQQKNNLENFALSICLAEGFPDGEINSEAFSAVGAYVELGAYPVEAYEEVSELAKKFLEKKYISKNGESKLTVMKCIDLSQSSELSAIKDKYTRHI
>NZ_CP045154.1|WP_002211898.1|2103459_2104287_+|SDR-family-oxidoreductase
MKKVAIIGLGWLGMPLAQSLSRRGIDVVGSKTTPDGVDAARMSGINCYPLVLTPELICEPDDLAQLMAVDALVITLPASRTTAGGDHYFQAVQQVVDSALAFGVPRIIFTSSTSVYGETRGRIKESSPLQPVTVAGKTLMALEQWLHQLPHTSVDILRLAGLVGTDRHPGRFLAGKTGVKGGSQGVNLVHQEDVIAAIELLLNRPKGGHLYNLCAPIHPRKRDFYPACARALQLTPPEFAVEEQEGANREIDGSKICSELGFEYLYPDPSRMPLN
>NZ_CP045154.1|WP_002231208.1|2103036_2103084_-|his-operon-leader-peptide
MNRVQFNHHHHHHPD
>NZ_CP045154.1|WP_002211896.1|2101854_2102754_-|ATP-phosphoribosyltransferase
MLDKTRLRIAMQKSGRLSDESQELLSRCGIKINLQQQRLIAFAENMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGDDPRYFTLRRLDFGGCRLSLAAPLDAEYTGPQCLQDTRIATSYPHILKQYLDKQGVRFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMSVDKQQLIDRLMTRIQGVIQARESKYIMMHAPSERLDEIITLLPGAERPTILPLAGDKSRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME
>NZ_CP045154.1|WP_002211904.1|2112327_2113758_-|exodeoxyribonuclease-I
MSDKNKQPTFYVHDYETFGQRPALDRPAQFAGVRTDLDFNLVEEPLVIYCKPADDYLPQPEAVMITGITPQHALANGVNEAEFSRQIHQAFSVPGTCILGYNNIRFDDEVSRNIFYRNFYDPYAYSWQGGNSRWDLLDVMRACYALRPEGIVWPENDDGLPSFKLEHLTKANGVEHLQAHDAMSDVYATIAMAKLVKQAQPRLFDYLYQHRSKHKINALIDIAEMTPLVHVSGMFGAARGNTSWVAPLAWHPENKNAVIMCDLAGDMSPLLELDSDTLRERLYTRRDKLQAQESAIPIKLVHINKCPVLAPAKTLLPENADRLGIDRQRCLQNLQLLRQNPQVREKVVALFAQAEPFAVTDDVDTQLYNGFFSDADRATIKIIQQTESQNLPALDLTFQDPRLEALLFRFRARNYPNTLNDSEQQRWLQHRREALSPERVQDYVLQLEQFYNQYEDDKEKLALLKALFEYAKGLVS
>NZ_CP045154.1|WP_002211905.1|2114050_2115160_+|NAD-dependent-epimerase/dehydratase-family-protein
MKKLLLTGATGFLGGAVLEKLLLASSDFNYLLLVRANTPEQGLMRIRENLEKFYLPNELINKININHVLLGDLAEPDSFINDVRIDDVTHVINCAAIASFGNNPLIWKVNVEGTLAFGKRMAQVAGLQRFVHVGTAMACTPEADTVVDERVLSTENDAHLVEYTKSKSAIECLLAEHCPTLPLVFARPSIVVGHTRLGCQPSSSIFWVFRMALMLRKFMCSLDDHIDVIPVDYCADALLYILEYPNLPDDIYHISAGEKGSVSFSEIDQAMSVAAKQKPVGVNYSQVEYTALVQMRNQLKGIFGPCNERLMLKAMRLYGSFAMLNVRFSNERLLSLGMPRTPRFTDYIARCVESSHGMTIQQQMAVDFK
>NZ_CP045154.1|WP_002217522.1|2115593_2115911_+|DUF496-family-protein
MDNASKPTFQDVLEFVRMFRRKNKLQREIVDNEKKIRDNQKRVLLLDNLSEYIKPGMSIEEVQAIIANMRGDYEDRVDDYIIKNADLSKERRELSKKLKAMGEVK
>NZ_CP045154.1|WP_002209743.1|2116281_2117490_+|IS256-family-transposase
MDEKKLKALAAELAKGLKTEADLNAFSRMLTKLTVETALNAELTEHLGHEKNTPKSGSNTRNGYSSKTLLCDDGEIELNTPRDRENTFEPQLIKKNQTRITQMDSQILSLYAKGMTTREIVATFKEMYDADVSPTLISKVTDAVKEQVAEWQNRQLDALYPIVYMDCIVVKVRQNGSVINKAVFLALGINTEGQKELLGMWLAENEGAKFWLSVLTELKNRGLQDILIACVDGLKGFPDAINSVYPQTHIQLCIIHMVRNSLKYVSWKDYKAVTSGLKMVYQAPTEEAALMALDKFAEAWDDKYPQISKSWRTHWENLNTFFGYPPDIRKAIYTTNAIESVNSVIRAAIKKRKVFPTDDSVRKVVYLAIKDASKKWSMPIQNWRLAMSRFIIEFGDRLSDHL
>NZ_CP045154.1|WP_002216388.1|2117452_2120605_-|inverse-autotransporter-beta-barrel-domain-containing-protein
MSLYRISSLHQAKQLNKNKQLNKTRISKSVVWANIVIQAIFPLSIAFTPAVMAAETVGASDEKPRSASQAEQSTANAATRLASILTNDDSAKQASSIARGTAANAGNEALQKWFNQFGSAKVQLNLDEKLSLKGSQLDVLLPLTDSPDLLTFTQLGGRYIDDRVTLNVGLGQRHFFAQQMLGYNLFIDHDASYSHTRIGVGAEYGRDFINLAANGYFGVSGWKNSPDLDKYDEKVANGFDLRSEAYLPTLPQLGGKLIYEQYFGDEVGLFGVDNRQKNPLAVTLGVNYTPIPLFTVGVDHKMGRAGMNDTRFNLGFNYAFGTPLTHQLDSDAVAIKRSLMGSRYNLVDRNNQIVMKYRKQNRVTLELPARVSGAARQTMPLVANATAQQGIDRLEWEASALTLAGGKITGSGNNWQITLPSYLSGGEGNNTYRISAIAYDTLGNASPVAYSDLVVDSHGVNTNASGLTAAPEILPANASASSVIEFNIKDNANQPITGIADELAFSLELVELPEELAKAKARSVPLKTVSHTLTKITESAPGIYQATLTSGSKPQLINITAQINGVPLADVQTKVTLIADESTATLQTSSLQIITNGSLADDTDANQIRAVVVDAYGNKLSGVQVNFTVGNNAKITETTLSDKQGGVTAAITSTKAGTYTVTAELNGVTQQIDVNFIPDAGTATLDDSDEYKLQWVTNGQVADGESTNSVQLTVVDKFGNTVPGVDVAFTTDIGAIISEVTPTDANGVATAKIISSQAKSHTVKATLNRKEQTVEVNFIADTATAEITANNFTVEVDGQVAGSGTNQVQALVVDKKGNPVANMTVNFTATNGVVVETTSAKTDENGKVTTNLSMTNVGGTISTVTATMINSANVTSTQDKPVIFYPDFTKATLNTPANTYSGFNINSGFPTTGFKNTHFQLSPHGITGANSDYDWVSSHPNVSVSNTGAITLQDNPGGKVTITATWKHDSSKVFTYDFTLNYWVGLYSSTNLSWAQANASCINAGMRLPTNREVSAGQDVRGVGSLLSLSIILCNCHRIKGDRSGGHRTR
>NZ_CP045154.1|WP_002211911.1|2121629_2122934_+|MFS-transporter
MSNFNHYPDPTLNSAIKKAWYRLMPLMFIMYFVAFIDRINVGFAKDAMSADIGLSQSAFALGAGIFFAAYALFGIPANLMMNKLGAKVWLSSTTVVWGLLSAGTGLVSNEYQFVILRFLLGVAEAGFYPGILLLASIYFPNKIRASVIGIFVLGVPAALTLGSPISGALLDMQGFLGQPGWFWMFLLEGLPAVGLGIFAFFYLDDSPATARYLNPEEKQALLTQLSIEQSDTESSSVKAVLLSPKVWHLALIYGTIQVGVYGLIFFLPSQVATLLGSTLGFKESLVAAIPWAFSALGVYYIPRYADRKTHRRNPIATLNLVVAAIGLIISAYASPVLAIAALCLCAIGFLAVQPIFWTFPAQILSGKALAAGIGFCTTMGAFFSFLAPIIRVEAESQFNSPPAGLITLALFSLLSATLIFSLKFWPAKATAEVI
>NZ_CP045154.1|WP_002211912.1|2122942_2123365_-|thiol-disulfide-oxidoreductase-DCC-family-protein
MSAPLPYIKPGERVIIYDGVCALCTGWVNFLIRHDRRHTVRLSAVQSKKGHALLEWAGLPTDKINTLVLIENQQVYLRSEAIFRVIANLPWPWRILGVLRIFPRPLRDRCYDGIALNRYRLFGRYDAVRKLKADHERRFL
>NZ_CP045154.1|WP_002216393.1|2123792_2124533_+|SDR-family-oxidoreductase
MNLKGKKALVTAAGQGIGFNTATLFARKGAEVIASDINIAALSNIPGITAVSLDVTDTLAINDVAQAIGPIDVLFNCAGVVHSGDILTCSEQEWQFALDLNVTAMFHMIRAFLPGMIACQQGSIINMSSVASSIKGVPNRFAYSTSKAAVIGLTRSVAADYVTQGIRCNAICPGTVESPSLRQRIAVQAHAEGRSEADVFQAFAARQPIGRIGKAEEIAQLALYLASDASAYTTGTIHIIDGGWSN
>NZ_CP045154.1|WP_002211916.1|2124580_2125423_+|fumarylacetoacetate-hydrolase-family-protein
MKLLRYGPVGEERPALLDELGEIRDLSAHIEDISGKFLLPATLYKLRQLDSASLPLVRGEQRLGACVGHVGKFICVGLNYADHAAETGAEIPQEPVIFNKWTSAIIGPNDDIEIPRNSVKTDWEVELGVVIGTGGRYIGEANAMSYVAGYCVVNDISEREFQLEHGGTWDKGKGCDTFGPIGPWLVTRDEIPDPHQLGLWLDVDGRRYQNGSTRTMIFKIPQIISYLSRFMSLQSGDVISTGTPPGVGLGQKPPVYLHAGQIMRLGIEGLGEQCQKTIQA
>NZ_CP045154.1|WP_002211917.1|2125454_2126732_+|L-fuconate-dehydratase
MTIITALRTEDVRFPTSLELDGSDAMNPDPDYSAAYVILDTDNPALSGHGLTFTIGRGNEICCVAIHALEHLIVGRDLASMTANMGKFWREFTSDSQLRWIGPEKGAIHLATGAVINAVWDLWSKAEGKPLWRLVADMSPEELVRCIDFRYITDCITPEEALTLLQQRAHNKALRLEKLQDEGYPCYTTSAGWLGYPDDKLRRLCQDAVDAGFDYLKLKVGRDLEDDIRRVRITREVLGPDRKLMIDANQIWETNEAIPWVNQLAFANPWFIEEPTNPDDIEGHRRIRQGVAPVKVATGEMCQNRIMFKQFIMREAIDVVQIDACRLGGVNEVLAVMLMAAKYDLPVCPHAGGVGLCEYVQHLAMIDYLCIAGTDKGRVIEYVDHLHEHFVHPCVIKNAAYMPPEQPGFSIEMHQSSIEKYRFRV

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Crispr_ID: NZ_CP045154_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045154_5

3088686-3088895

TypeI-F

I-F

Consensus_repeat	Method
TTTTCTAAGCTGCCTGTGCGGCAGTGAAC	CRISPRCasFinder
TTTTCTAAGCTGCCTGTGCGGCAGTGAAC	CRT
TGTTCACTGCCGCACAGGCAGCTTAGAAAA	PILER-CR

3 spacers

cas1,cas3f,cas8f,cas5f,cas7f,cas6f

The CRISPR arrays of NZ_CP045154_5

>merge|NZ_CP045154|5|3088686-3088895|CRISPRCasFinder,CRT,PILER-CR
ATTTGATTATTGCCTGTGCGGCAGTGAACTCAGGGGACTGGCGAACAATGTCTTTCATGATTTTCTAAGCTGCCTGTGCGGCAGTGAACGAAAAGGTAAGATGGGCAAGCTTCTAGTAGTTTTTCTAAGCTGCCTGTGCAGCAGTGAACATTATCTGAATGGCATTTTCTTTGGCGCAGATTTTCTAAGCTGCCTGTGCGGCAGTGAACA

>NZ_CP045154|5|5|3088686-3088894|CRISPRCasFinder
ATTTGATTATTGCCTGTGCGGCAGTGAAC	TCAGGGGACTGGCGAACAATGTCTTTCATGA
TTTTCTAAGCTGCCTGTGCGGCAGTGAAC	GAAAAGGTAAGATGGGCAAGCTTCTAGTAGT
TTTTCTAAGCTGCCTGTGCAGCAGTGAAC	ATTATCTGAATGGCATTTTCTTTGGCGCAGA
TTTTCTAAGCTGCCTGTGCGGCAGTGAAC

>NZ_CP045154|5|3|3088686-3088894|CRT
ATTTGATTATTGCCTGTGCGGCAGTGAAC	TCAGGGGACTGGCGAACAATGTCTTTCATGA
TTTTCTAAGCTGCCTGTGCGGCAGTGAAC	GAAAAGGTAAGATGGGCAAGCTTCTAGTAGT
TTTTCTAAGCTGCCTGTGCAGCAGTGAAC	ATTATCTGAATGGCATTTTCTTTGGCGCAGA
TTTTCTAAGCTGCCTGTGCGGCAGTGAAC

>NZ_CP045154|5|3|3088746-3088895|PILER-CR
TTTTCTAAGCTGCCTGTGCGGCAGTGAACG	AAAAGGTAAGATGGGCAAGCTTCTAGTAGT
TTTTCTAAGCTGCCTGTGCAGCAGTGAACA	TTATCTGAATGGCATTTTCTTTGGCGCAGA
TTTTCTAAGCTGCCTGTGCGGCAGTGAACA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045154.1\|WP_002210192.1\|3089231_3090476_+\|mechanosensitive-ion-channel	unknown	unknown	gnl\|CDD\|223740
NZ_CP045154.1\|WP_002210196.1\|3094568_3095624_-\|glycosidase	unknown	unknown	gnl\|CDD\|350124
NZ_CP045154.1\|WP_002213840.1\|3093603_3094542_-\|DUF1861-family-protein	unknown	unknown	gnl\|CDD\|378102
NZ_CP045154.1\|WP_002210197.1\|3095770_3096595_-\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472
NZ_CP045154.1\|WP_002211867.1\|3080338_3081343_-\|type-I-F-CRISPR-associated-protein-Csy3	cas7f	cd09677_cas7f_CAS-I-F	gnl\|CDD\|378222
NZ_CP045154.1\|WP_002211865.1\|3078676_3079696_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381305
NZ_CP045154.1\|WP_002210200.1\|3099137_3100178_+\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380502
NZ_CP045154.1\|WP_002210199.1\|3097579_3098866_-\|carbohydrate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224567
NZ_CP045154.1\|WP_002211864.1\|3078162_3078666_+\|formaldehyde-activating-enzyme	unknown	unknown	gnl\|CDD\|224708
NZ_CP045154.1\|WP_002222491.1\|3082307_3083654_-\|type-I-F-CRISPR-associated-protein-Csy1	cas8f	cd09675_cas8f_CAS-I-F	gnl\|CDD\|274203
NZ_CP045154.1\|WP_002216551.1\|3076424_3076634_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045154.1\|WP_002211868.1\|3081360_3082311_-\|type-I-F-CRISPR-associated-protein-Csy2	cas5f	cd09676_cas5f_CAS-I-F	gnl\|CDD\|187807
NZ_CP045154.1\|WP_002211866.1\|3079773_3080328_-\|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	cas6f	cd09674_cas6f_CAS-I-F	gnl\|CDD\|378224
NZ_CP045154.1\|WP_002228501.1\|3084062_3087350_-\|type-I-F-CRISPR-associated-helicase-Cas3	cas3f	cd09673_cas3f_CAS-I-F	gnl\|CDD\|187804
NZ_CP045154.1\|WP_002211863.1\|3076757_3078116_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340874
NZ_CP045154.1\|WP_002210201.1\|3100194_3101583_+\|phosphomannomutase/phosphoglucomutase	unknown	unknown	gnl\|CDD\|185312
NZ_CP045154.1\|WP_002210193.1\|3091052_3092327_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045154.1\|WP_002210194.1\|3092365_3093481_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045154.1\|WP_002210198.1\|3096595_3097471_-\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224096
NZ_CP045154.1\|WP_002210191.1\|3087346_3088327_-\|type-I-F-CRISPR-associated-endonuclease-Cas1	cas1	cd09718_cas1_CAS-I-F	gnl\|CDD\|132676

Protein	Function_ID	Function_description	E-value
NZ_CP045154.1\|WP_002210192.1\|3089231_3090476_+\|mechanosensitive-ion-channel	gnl\|CDD\|223740	COG0668, MscS, Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane].	2.65074e-32
NZ_CP045154.1\|WP_002210196.1\|3094568_3095624_-\|glycosidase	gnl\|CDD\|350124	cd18612, GH130_Lin0857-like, Glycoside hydrolase family 130 such as Listeria innocua beta-1,2-mannobiose phosphorylase. This subfamily contains the glycosyl hydrolase family 130 (GH130), as classified by the carbohydrate-active enzymes database (CAZY), enzymes that are phosphorylases and hydrolases for beta-mannosides, and includes Listeria innocua beta-1,2-mannobiose phosphorylase (Lin0857). hey possess 5-bladed beta-propeller domains similar to families 32, 43, 62, 68, 117 (GH32, GH43, GH62, GH68, GH117). GH130 enzymes are involved in the bacterial utilization of mannans or N-linked glycans. Structure of Lin0857 shows beta-1,2-mannotriose bound in a U-shape, interacting with a phosphate analog at both ends. Lin0857 has a unique dimer structure connected by a loop, with a significant open-close loop displacement observed for substrate entry. A long loop, which is exclusively present in Lin0857, covers the active site to limit the pocket size.	9.75278e-165
NZ_CP045154.1\|WP_002213840.1\|3093603_3094542_-\|DUF1861-family-protein	gnl\|CDD\|378102	pfam08950, DUF1861, Protein of unknown function (DUF1861). This hypothetical protein, found in bacteria and in the eukaryote Leishmania, has no known function.	6.29599e-176
NZ_CP045154.1\|WP_002210197.1\|3095770_3096595_-\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	4.72016e-69
NZ_CP045154.1\|WP_002211867.1\|3080338_3081343_-\|type-I-F-CRISPR-associated-protein-Csy3	gnl\|CDD\|378222	pfam09615, Cas_Csy3, CRISPR-associated protein (Cas_Csy3). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This entry, typified by YPO2463 of Yersinia pestis, is a CRISPR-associated (Cas) entry strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy3, for CRISPR/Cas Subtype Ypest protein 3.	0
NZ_CP045154.1\|WP_002211865.1\|3078676_3079696_+\|aldo/keto-reductase	gnl\|CDD\|381305	cd19079, AKR_EcYajO-like, Escherichia coli YajO and similar proteins. Escherichia coli YajO is the prototype of this family. It is an uncharacterized aldo/keto reductase family oxidoreductase.	6.34333e-143
NZ_CP045154.1\|WP_002211864.1\|3078162_3078666_+\|formaldehyde-activating-enzyme	gnl\|CDD\|224708	COG1795, COG1795, Formaldehyde-activating enzyme nesessary for methanogenesis [Energy production and conversion].	1.50048e-90
NZ_CP045154.1\|WP_002222491.1\|3082307_3083654_-\|type-I-F-CRISPR-associated-protein-Csy1	gnl\|CDD\|274203	TIGR02564, conserved_hypothetical_protein, CRISPR type I-F/YPEST-associated protein Csy1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This protein family, typified by YPO2465 of Yersinia pestis, is a CRISPR-associated (Cas) family strictly associated with the Ypest subtype of CRISPR/Cas locus. This family is designated Csy1, for CRISPR/Cas Subtype Ypest protein 1.	0
NZ_CP045154.1\|WP_002228501.1\|3084062_3087350_-\|type-I-F-CRISPR-associated-helicase-Cas3	gnl\|CDD\|187804	cd09673, Cas3_Cas2_I-F, CRISPR/Cas system-associated protein Cas3/Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas3/Cas2 fusion; This protein includes both DEAH and HD motifs for helicase and N-terminal domain corresponding to Cas2 RNAse; signature gene for Type I and subtype I-F.	0
NZ_CP045154.1\|WP_002211868.1\|3081360_3082311_-\|type-I-F-CRISPR-associated-protein-Csy2	gnl\|CDD\|187807	cd09676, Csy2_I-F, CRISPR/Cas system-associated RAMP superfamily protein Csy2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; predicted Cas5 ortholog.	1.12008e-157
NZ_CP045154.1\|WP_002211866.1\|3079773_3080328_-\|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	gnl\|CDD\|378224	pfam09618, Cas_Csy4, CRISPR-associated protein (Cas_Csy4). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This protein family, typified by YPO2462 of Yersinia pestis, is a CRISPR-associated (Cas) family strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy4, for CRISPR/Cas Subtype Ypest protein 4.	1.71931e-94
NZ_CP045154.1\|WP_002210200.1\|3099137_3100178_+\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|380502	cd06279, PBP1_LacI-like, ligand-binding domain of an uncharacterized transcription regulator from Corynebacterium glutamicum and its close homologs from other bacteria. This group includes the ligand-binding domain of an uncharacterized transcription regulator from Corynebacterium glutamicum and its close homologs from other bacteria. This group belongs to the LacI-GalR family repressors and are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the sugar-binding domain of ABC-type transport systems that contain the type 1 periplasmic binding protein-like fold. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding.	1.56156e-83
NZ_CP045154.1\|WP_002211863.1\|3076757_3078116_+\|MFS-transporter	gnl\|CDD\|340874	cd17316, MFS_SV2_like, Metazoan Synaptic vesicle glycoprotein 2 (SV2) and related small molecule transporters of the Major Facilitator Superfamily. This family is composed of metazoan synaptic vesicle glycoprotein 2 (SV2) and related small molecule transporters including those that transport inorganic phosphate (Pht), aromatic compounds (PcaK and related proteins), proline/betaine (ProP), alpha-ketoglutarate (KgtP), citrate (CitA), shikimate (ShiA), and cis,cis-muconate (MucK), among others. SV2 is a transporter-like protein that serves as the receptor for botulinum neurotoxin A (BoNT/A), one of seven neurotoxins produced by the bacterium Clostridium botulinum. BoNT/A blocks neurotransmitter release by cleaving synaptosome-associated protein of 25 kD (SNAP-25) within presynaptic nerve terminals. Also included in this family is synaptic vesicle 2 (SV2)-related protein (SVOP) and similar proteins. SVOP is a transporter-like nucleotide binding protein that localizes to neurotransmitter-containing vesicles. The SV2-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.50877e-50
NZ_CP045154.1\|WP_002210201.1\|3100194_3101583_+\|phosphomannomutase/phosphoglucomutase	gnl\|CDD\|185312	PRK15414, PRK15414, phosphomannomutase.	0
NZ_CP045154.1\|WP_002210199.1\|3097579_3098866_-\|carbohydrate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224567	COG1653, UgpB, ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism].	2.85244e-50
NZ_CP045154.1\|WP_002210198.1\|3096595_3097471_-\|sugar-ABC-transporter-permease	gnl\|CDD\|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	2.26211e-58
NZ_CP045154.1\|WP_002210191.1\|3087346_3088327_-\|type-I-F-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|132676	TIGR03637, cas1_YPEST, CRISPR-associated endonuclease Cas1, subtype I-F/YPEST. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the YPEST subtype of CRISPR/Cas system.	0

>NZ_CP045154.1|WP_002210191.1|3087346_3088327_-|type-I-F-CRISPR-associated-endonuclease-Cas1
MENAIHSSDLKTILHSKRSNIYYLEYCRVLVNGGRVEYVTDEGKQSLYWNIPIANTTVIMLGTGTSVTQAAMREFARAGVLVGFCGGGGTPLFAANDVEVNVSWLTAQSEYRPTEYLHDWVSFWFDDEKRLAAAVAFQRIRIAQIQQHWLSSHIQRESLFPVNHDQLLFILTRFEQNLANCLTSNDLMVQEAVLTKALYKLAANTVNYGDFTRAKRGGGIDLANRFLDHGNYLAYGLAATATWVIGLPHGLSVLHGKTRRGGLVFDVADLIKDALVLPQAFIAAMQGEEEQEFRQRCISGFQRTEALDVMIDGIKETAALCSQVPR
>NZ_CP045154.1|WP_002228501.1|3084062_3087350_-|type-I-F-CRISPR-associated-helicase-Cas3
MNILLISQCHKRALNETRRILDQFAERKGDRTWQTAITQEGLNTLRKLLRRTARRNSAVACHWIKSNNQSELLWIVGNLRRFNAEGTVPTNTTQRDILRSQDENNWHSVETIALLAGIAGLFHDFGKANVLFQQGLQGQGKTYQPYRHEWVSLRLFQAFVEQKNDIQWLTALSQINPADETTLMSNLVKDGLDDYTNPLAALPPLAKTIAWLILSHHRLPVYPSKDYHRPPKVEEIDDWLHQQLMPVWNSTNMDSGDWREKDKLDVWRFPHGTPLQSAEWCKKAQKFAKRALRQPSLVNDGHLNQRFTSHMARLVLMLADHHYSSLPATPGWQDKNYQVFANTHNKMRDANAHSKTIEMKQRLDEHNIGVGQNALLLGRSLPHIRKTLPAITRHKGFKQRSVQEKYRWQDKAFDLAVTLRERSLQQGFFGVNMASTGCGKTFANARIMYGLSDEKQGCRFSVALGLRTLTLQTGTALQQKLTLQKDDLAVLIGSQSVLQLYQLNNDKLEPRGTGSQSADKFFSEHQYVSYDGSLDDGRLSTWLSNNDRLKRLLCAPVLVCTIDHLIPATESLRGGKQIAPMLRLLTSDLVLDEPDDFDRNDLPALCRLVNWAGMLGSRVLLSSATLPPALVQALFNAYRAGRADYQQASGQPDTPVNICCAWFDEHGVAQQDIQQSKDFIQHHGDFITRRVGKLSTAEVLRRAELIPVSSASVKNGSVLDAMAAVMRDSMLRLHQAHHQTHPSEKTVSVGVVRMANIDPLVAIAQRLYAMAAPENYRIHYCVYHSQHPLAVRSAIERRLDVTLTRYQPNALWQVAEIEHALQHHPEQHHLFVVLATSVVEVGRDHDYDWALAEPSSMRSFIQLAGRVQRHRQVAPQMANMHILQKNFKALTQKDPAIPVYCKPGFETTRCRLNTHDLDKLLLPSQYKVINAISRIQERTKLEPRDNFVDLEHLSLRLILQGSAEPLKYYAALWWRKQATWSGEQQRCPPFRQSSPDEQHNLWIDDEADKPVFKRLDSDQIEWKVSDGFQDVELTLAAGNSAWIDTDCLRIYQWLAESLNKELNEVSRQFGEVRLPKKDGERWHYHPLLGVFGALD
>NZ_CP045154.1|WP_002222491.1|3082307_3083654_-|type-I-F-CRISPR-associated-protein-Csy1
MSDEGLAAFIVSYIKSREQPKLEAFDKEAEKRLAGLTQAEDIALAQQEIAQQRQELIARYEVRNWLTDAANRAGQIKLATHAPKYTHSDSKSSGILNIELQSKKKDYFSSVDLAEQASDVIGNAAVFDLVKLLQSECEGGSLIKCLEQGDNSVLKLFSNDDELVEEWTTKFKSILNNEKFTSHKLAKQFYFPVGPDQYHLLSPLFSSSLAQAMHQRIIEARFSDQSKEAKAAHKAGRWHPTVRVLYLDTAVQHIGGTKPQNISYLNSVRGGKVWLLPCGAPSWKNIQKPPIKYRSIFHDRSEFTVLARNNLWQMQLYLLGVKPLSNTMDIRAARLACCDEIIDILFNYVAEIQNLDGTNGWSDAEDCKLKRSEQLWLDPTRAMDDPVFKLEREKEDWKQEVSQDFGYWLNRWLQHDELVFGYVEQREWSSLFKQRLREFEQGSLETSS
>NZ_CP045154.1|WP_002211868.1|3081360_3082311_-|type-I-F-CRISPR-associated-protein-Csy2
MSSLIVLHQVRVENANAIAGLTYGFPAITHFLGYSHALSRKLQSSHGLTLRGCAVICHYQQVHAYLSGWDYVFSLTRNPLTKEAKTAAFNEEGRMHMTVSLVIECDGTIANGDDGANALEKHLASLCLTQRLAGGTITNIRRVKVINYPETEVATRRLLCRLLPGFALLDRSELLAEHLNRLRQTNPQAEMLDAWLDFSALKIQAIPPQSDTPVESGAPAPWGYVGKPAAGYLVPIVTGYRAISPLYAPGEVDKTRDPHTPFRFVESLYGIGEWRGLHRITDLRQLLWGYHQEGDNYLCRCALPASVDTYLLNDEE
>NZ_CP045154.1|WP_002211867.1|3080338_3081343_-|type-I-F-CRISPR-associated-protein-Csy3
MAKATIKTASVLAFERKLSNSDAMMYAGNWGQTDNWQPIIIKEKAVRGTISNRLKNALASDPAKLDAEIQKANLQRVDVAALPFDTDTLKMSFTLRVLGNLATPSVCNDQEYQAELASVINGYISEQSFSVLAARYAENLANGRFLWRNRVGAEDIKVCITSQTKSYQFDSNEFSLRQFSQPSKELTALAQEIEQGLAGNGFAFFTVDAFVRLGNGQEVFPSQELVLDSNSKKSKVLYQIDGIAALHSQKVGNALRTIDDWYPDATELALGPIAVEPYGSVTSRGKAYRQPKQKMDFYTLLDNWVTKGTVPAVEQQHYVMATLIRGGVFGEKGE
>NZ_CP045154.1|WP_002211866.1|3079773_3080328_-|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4
MDHYLDIRVLPDPEFSAQTLLEALFAKLHRALVATIPGRVGVSFPTAGKTLGSQLRLHGSRGDLLELQSAGWLKGLQDYCECSEILPVPADVKHRTIRRVQVKSSAQRLRRRSVSKGWLTEEQARLRIPDSHDKRCDLPFLRLKSRSSEQYFLLFIEQGTLQASATTGEFSAYGLSVNATIPWF
>NZ_CP045154.1|WP_002211865.1|3078676_3079696_+|aldo/keto-reductase
MDYIKLGHCGLQVSRLCLGTMNMGSKQWKPWVFDKAESTPLIKHALDCGINFIDLADFYSAGVGEEVVGRIVKNLMSRDELVLTTKVGYPIGHGPNNQGHSRKHIMASIDASLKRLGTDYIDIYMLHYFDINTPVEETWSAMNDIIHSGKARYTGVSTMFTWQLSKILWCCERNGFAKPINMQLQLNCAYREEEREMIPQCRDQGLGISAFSPLARGLLSCDFSSVRNKTDFFTQEMYADVTSLNIAQSVERVAKNRGITPAQVAQAWVLNHPGTDCMLVGADTIEQINSAVTALRISLNAEEHFELERNYTPCDVINDYTAGQRIAREARPPSGIFAP
>NZ_CP045154.1|WP_002211864.1|3078162_3078666_+|formaldehyde-activating-enzyme
MQMYIGEGFAGNGVNAAHINIMIGPRDGVVGQAFAASLASPSQGHYPFIVVIKPNVAAKPMTLYVNKAEIRSELHGRATWGASQAAVAKAVAEALLANLFPPEAEDDWCIITANWVNIDCDDIDEVYRNNYRACTTALHAAMAKTPKRDQLTHALTQLSNPFFTPKA
>NZ_CP045154.1|WP_002211863.1|3076757_3078116_+|MFS-transporter
MQTLPSEKIRMDDVPLNRFHIRIAGLTFGAHFIDGYILGLIGFALIQLKPIMALTPLWEGLLGSAALIGLFLGSLILGWISDYIGRQKIFSFSFVIITLASALQFFASTPEQLFILRVIVGIGIGGDYSVGHTLLAEFSPRKHRGVLLGAFSVIWTFGYVSASFVGHYLSMVSPEAWRWLLSSAALPALLILLVRIGTPESPRWLMGKGREDDAMAIVHKYFGPNVTLIDEEPATSTRRFLSLFGRKYWRRTAFNSLFFVCLVIPYFAIYTFLPSILNVMALSQNFATDLLLNGLLVVGALVGIVLTAFCSRRSFLISSFIFLATCLLLLSILPSNQTFWLIALFAAFTLVMSAVSNLVGVFPAESFPTEVRSMGVGFATSMSRLGSAIGTSLLPLAIVNYGMPVTTTLLAFVLIIGAIVSIAWAPETKGLTLVDASQSATTPRPPSSIIPN
>NZ_CP045154.1|WP_002216551.1|3076424_3076634_-|hypothetical-protein
MVIGDLLTETDRLFQKRTAAMDDLFSSPGPVRLILFVMAMCQPKYKAASAFYAYPSEKKVRDPPLNSYK
>NZ_CP045154.1|WP_002210192.1|3089231_3090476_+|mechanosensitive-ion-channel
MQQRISQWLERLGMEFSDVMSLTMVIGLILLISVMIHLVLHRVVLAALQRRGQQSQRIWQQAITKHKLFQRVALLLQGIIINLQAVLWLQNGSQTQAVIVTAAQVWIMAFALLALFSLLDTLLALLRQSSVAHQLPLRGICQGLKLVAAIFIGIMIVSLLMGRSPLLLLSGLGAMTAVLMLVFKDPILGLVAGIQLSANDMLKIGDWLEMPKYGADGAVTDIGLTTVKVRNWDNTVTTIPTYALISDSFKNWRSMSESGGRRIKRSINIDTTSVHFLSEQEQQRLTLNPLLQHYLSEKSQELNQYNQQIALDLSSPLNGRRLTNIGTLRAYLVAYLRAHLGIHQSMTLMVRQLAPTPEGLPLEVYAFTNTTIWAEYEGIQADIFDHIFAVVSEFDLRIHQTPSGNDMRSMLAKV
>NZ_CP045154.1|WP_002210193.1|3091052_3092327_-|hypothetical-protein
MKLLNTLVCIIGLTSFSSSAKLVNAEHLDALYQKVTVANKTELGLIHIYSEFPDYRWVKDPIEGVSAIDDVARAAIFYQRQYQATGSAADLEKVKSLVEFILYQRADNGYFYNFIYPDHSINKEYKTSVAEPNWWTWRALWALTQVYPTLVKTDNALAQRTRETIFATIDVIYKDFNFKQTRGEKEGVAVPEWLPHTAGDQASVLLMALSDAQALEAKPEIEKMMRSLAAGIMLMQVKDTSSPVNGAFLSWQNLWHGYGNSQAYALLVAGNRLGDRDMIKAAFNELDHFHPWLISNGLLNEFTVRQQGEKVTLIEQKKFSQIAYIIRPMVFANIKAWEISRDAVYLERAVDLSLWFFKNNPAQAQMYYPVTGIAFDGIDSATTVNKNSGAESTIEALLTLQLIESIPDAKRMLESALEKRNIKQ
>NZ_CP045154.1|WP_002210194.1|3092365_3093481_-|hypothetical-protein
MKHKKYLPLFLMAGICSVAQADNSPDVVSANNMDNRTFFAGDKIRIVKDGGETIEAVVELSDDNIGIVRIPKDEKAYFHGNWLAEYKIEHFRNEGRSTNSRPVHEIVFADGRVNFGDTGWNTGFLLKQVRFTSDSRNESNHKVDFRMVEMEIRPAWSKSIDKHWFMFEGIYLGKTGYEKNRTTGGDNNIGGDGYGFRPYYRYQVSDRLSVNTDVKMLVEDKDARGADNGRFQFYEALVNVNYRVADNVHVGIEVFRKEGQDFNHNGTKTANVLEQELRPWVAWNMGKNNFLFKMEPQLRRIGGQDGYRETSKAQKYIFNYSYPIADRVYLVAEYFYRVEHDKKFWDRGVRDNKSYSDTTTHFGKLGINYIF
>NZ_CP045154.1|WP_002213840.1|3093603_3094542_-|DUF1861-family-protein
MMRHAPPASVAQLFADYQKRTAHNTFSTGRLEFTGVGDKDVYNITAPFTSAGQVVIAGRVEARDSEHSTIVFFSEQQGQWAPVENAPTFQLQDPFFTRIEDELILGGVEINPHPDNPRQLIWHTVFFRGRDIHSLTRFASGPPGMKDIRLCHIQQGRIGVFTRPQGKIGGRGTIGYVEINNLEALTPETITSAELFEQQFNSEEWGGVNETHLLCDGTIGLLSHIACFDQHGRRHYYPGVFIFNPDTKNYTPIKIIAARDNFLPGATKRPDLVDVIFPGGLIVLPNNGWRLYVGASDAEAHWIDIEDPFSGF
>NZ_CP045154.1|WP_002210196.1|3094568_3095624_-|glycosidase
MMRYSGNPLITPQDITPSHPGFKVECAFNAGITKLGDETIMLIRIAESVIPESEGITVVPLLMEISGHWQVTTRVFKHDDPAYDFSDPRLISDIADPSTVYLTSLSHLRVARSHDGVTFVVDDQPFIFPANGDEAFGCEDARITQIDGAYYINYSAVSAKGICTALAVTQDFTDVKRLGLIFCPDNRDACLFPEKINGKYMTLHRPAPKHFGKPEIWLASSLDLLHWGDHRHLLGTSQDPWDALKLGGGAQMLKTEKGWLQIYHGVDATQRYSLGALLLDLEQPTKILAKSPVPLLQPQAPYELHGFFGNVVFTCGALIENDSLRVYYGAADECMCLAEMPLAQLWQHLSV
>NZ_CP045154.1|WP_002210197.1|3095770_3096595_-|carbohydrate-ABC-transporter-permease
MKKNINSLIIHLVMFSLALSWLYPYIWMVLSSFKQSADIYTTGLFGSAYSLDNYRFLFENSGRVEKPFLKTLFNSLFISTVVTVAVTLSSMFIGFALAKMQFKGQSLFRNLLFLQMVFPASMFIIPQFVLVRELGLLNTYSAMIVPFLMSSWGIFMISQSFQGTPNDYIHAAKIDNASLWQIMIYLMMPLNKAIIAIVALFTFVGTWDNFLWPLIVIQDESKMPLSVLLATFSKSYGVYVGPVIAGAVIQTIPIVVLFILFRKYFMQGMSLSLK
>NZ_CP045154.1|WP_002210198.1|3096595_3097471_-|sugar-ABC-transporter-permease
MTFLKLKDKQVGSVLAASYLGYTSIFWFYPFIWLAVLSLTEWRFVGIPTFNGLNNFILVMQDPLFWKSMLNVMRFLMYYLPIVFISSFLFAFGLQKLKHGRTFVALSFLLANVSSGVAYSIVFSKIFSQNGPLNTFLYDWFGFTLPWLTSPDFAMLSIALVVTWKFVGYYGLILFSGLNSIPKEIYSAAELDNTRTIKRLFHITLPMINPQLIMVLVLAITVSFAIFTEPYLITGGGPLNSTTTPMIVMYETAFMKMQPSWAATMSIFIALISFGIILGVRKLLERKVEIV
>NZ_CP045154.1|WP_002210199.1|3097579_3098866_-|carbohydrate-ABC-transporter-substrate-binding-protein
MLEKMKNTLISLAIASSCVVFTGCDNDTASAKNEKQDITLWIAPNNVQEAFWSEVVGEWNKQPDKKKVVFSTIPAAGSSEEAIMNAIASDRAPDISENIFTGFGSQLADLGQVVDLSTLDGYENLISTRQMTDIMDNWRYNGKNYILPIYMNPVLFWWRGDLLKEQGFSEVPKTYDEVYALSEKYTIPDKRYAIQATSGRNWWDRWFDFIALYYAQSDGKPYIANQQASYDNQAGRDVLDFMHTLFSKKWTLYDFGQDDPLVTGKVLGAVRGPWDISRYQQQYPEILKHIKMGPMLVKEQQDKPHTFADGKGLVLFSHSKVKPEAWEFIQWVFSQPKFDKRWMELTGMPPARADLLTNPFFAEYYQEHPYAAAYAEYVNVAIPPVSSGETVEIQRSMTQMIEKTAFNTATPDEALQQSIKEVNAILKP
>NZ_CP045154.1|WP_002210200.1|3099137_3100178_+|LacI-family-DNA-binding-transcriptional-regulator
MTTGKKRETLKTIAETLNVTHTTVSNVFNRPEKVSPELREKILAYAESINYHGPAGAGRFLRTGKCGTLGVIFNDNLSYVFSDRHDIALMRGIAEECEKNGINIALMPLKTNNALKKRMMGALVDGYILNATYNNDEVVQAALTSGLPVITTDIKLQNFTCVSIDDGAAMQAICHHLLAAGHKKFGIVSFPVKRLPGELTSLAEFSTDYDNGVAFGRISACITALSDAGIDLHTSYVAEQPHSETGGEKAAKALLAKEPGISAIICLSDRFAFGVYQFCQDHNIPVPGQIAITGFDDIDIQDPPVGLTTIRQPTVLKGREAARALISGQLDNDISLDFELVVRDSA
>NZ_CP045154.1|WP_002210201.1|3100194_3101583_+|phosphomannomutase/phosphoglucomutase
MEKLTCFKAYDIRGKLGSELNEEIAYRIGRAYCQWLKPAKVVVGGDARATSVELKNALAKGLMDGGADVIDIGMVGTEEVYFATRFYGVDGGIQVTASHNPIDYNGMKLVKKDAQPISGDNGLYEIQRLAQDNHFAPPGVRGQLETQLVREHYVEHLLSYIDLNALLPMKIVVNAGNGAAGPTLDALEAALAKRKVPISFIKINHQPDSSFPNGIPNPMLPENQWSTRQAVCEHQADLGIAWDGDFDRCFFFDHLGNFIEGYYIVGLLAEKFLLTNNMGKATHNTDKIIHDPRLTWNTIDIVQTLNGTAIESKTGHAFIKDAMRHHDAVYGGEMSAHHYFREFGYCDSGMIPWLLVIELLSKKTTSLFSLIESRKAKFPVSGELNFTVSDPKTKIQQIKQFYADSAIHVTGIDGLSMEFEHWRFNLRSSNTEPLVRLNIETRGDVTLLEQKTAQLTQLLYPK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP045154_2	2.8\|1429964\|32\|NZ_CP045154\|CRISPRCasFinder,CRT	1429964-1429995	32	NZ_CP045154.1	2549031-2549062	0	1.0

1. spacer 2.8|1429964|32|NZ_CP045154|CRISPRCasFinder,CRT matches to position: 2549031-2549062, mismatch: 0, identity: 1.0

agactgatgcaagatggcggtatgcgtacaga	CRISPR spacer
agactgatgcaagatggcggtatgcgtacaga	Protospacer
********************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP045154_2	2.8\|1429964\|32\|NZ_CP045154\|CRISPRCasFinder,CRT	1429964-1429995	32	MT374852	Yersinia phage vB_YpM_3, complete genome	12-43	0	1.0
NZ_CP045154_2	2.4\|1429962\|34\|NZ_CP045154\|PILER-CR	1429962-1429995	34	MT374852	Yersinia phage vB_YpM_3, complete genome	10-43	1	0.971
NZ_CP045154_4	4.2\|2112174\|32\|NZ_CP045154\|PILER-CR,CRISPRCasFinder,CRT	2112174-2112205	32	MH616963	CrAssphage sp. isolate ctbg_1, complete genome	86942-86973	7	0.781
NZ_CP045154_5	5.1\|3088715\|31\|NZ_CP045154\|CRISPRCasFinder,CRT	3088715-3088745	31	CP049262	Cronobacter sakazakii strain CS-09 plasmid pCsaCS09b, complete sequence	69637-69667	7	0.774
NZ_CP045154_5	5.3\|3088835\|31\|NZ_CP045154\|CRISPRCasFinder,CRT	3088835-3088865	31	NC_021534	Vibrio phage pYD38-A genomic sequence	3299-3329	7	0.774
NZ_CP045154_5	5.3\|3088835\|31\|NZ_CP045154\|CRISPRCasFinder,CRT	3088835-3088865	31	JF974294	Aeromonas phage pIS4-A genomic sequence	21966-21996	7	0.774
NZ_CP045154_5	5.4\|3088776\|30\|NZ_CP045154\|PILER-CR	3088776-3088805	30	NZ_CP031943	Nostoc sphaeroides strain Kutzing En plasmid p2, complete sequence	4007-4036	7	0.767
NZ_CP045154_5	5.5\|3088836\|30\|NZ_CP045154\|PILER-CR	3088836-3088865	30	NZ_CP013487	Vibrio alginolyticus strain ATCC 33787 plasmid pMBL287, complete sequence	166773-166802	7	0.767
NZ_CP045154_4	4.2\|2112174\|32\|NZ_CP045154\|PILER-CR,CRISPRCasFinder,CRT	2112174-2112205	32	NZ_CP010358	Acinetobacter johnsonii XBB1 plasmid pXBB1-8, complete sequence	46720-46751	8	0.75
NZ_CP045154_4	4.2\|2112174\|32\|NZ_CP045154\|PILER-CR,CRISPRCasFinder,CRT	2112174-2112205	32	NC_019694	Oscillatoria acuminata PCC 6304 plasmid pOSCIL6304.02, complete sequence	20911-20942	8	0.75
NZ_CP045154_5	5.2\|3088775\|31\|NZ_CP045154\|CRISPRCasFinder,CRT	3088775-3088805	31	NZ_CP031943	Nostoc sphaeroides strain Kutzing En plasmid p2, complete sequence	4007-4037	8	0.742
NZ_CP045154_2	2.7\|1429903\|33\|NZ_CP045154\|CRISPRCasFinder,CRT	1429903-1429935	33	NZ_CP040366	Bacillus flexus isolate 1-2-1 plasmid punnamed3, complete sequence	923-955	9	0.727
NZ_CP045154_4	4.2\|2112174\|32\|NZ_CP045154\|PILER-CR,CRISPRCasFinder,CRT	2112174-2112205	32	MT774386	CrAssphage cr110_1, complete genome	42858-42889	9	0.719
NZ_CP045154_4	4.2\|2112174\|32\|NZ_CP045154\|PILER-CR,CRISPRCasFinder,CRT	2112174-2112205	32	NZ_CP028934	Campylobacter jejuni strain FORC_083 plasmid pFORC_083_2, complete sequence	25849-25880	9	0.719
NZ_CP045154_5	5.3\|3088835\|31\|NZ_CP045154\|CRISPRCasFinder,CRT	3088835-3088865	31	MF679145	Escherichia coli plasmid pBJ114-96, complete sequence	37586-37616	9	0.71
NZ_CP045154_5	5.3\|3088835\|31\|NZ_CP045154\|CRISPRCasFinder,CRT	3088835-3088865	31	NZ_KP453775	Klebsiella pneumoniae strain ST11 plasmid pKP12226, complete sequence	60831-60861	9	0.71
NZ_CP045154_5	5.3\|3088835\|31\|NZ_CP045154\|CRISPRCasFinder,CRT	3088835-3088865	31	NZ_CP021340	Escherichia coli strain 95NR1 plasmid p95NR1A, complete sequence	67671-67701	9	0.71
NZ_CP045154_5	5.3\|3088835\|31\|NZ_CP045154\|CRISPRCasFinder,CRT	3088835-3088865	31	NZ_CP021336	Escherichia coli strain 95JB1 plasmid p95JB1A, complete sequence	67672-67702	9	0.71
NZ_CP045154_5	5.3\|3088835\|31\|NZ_CP045154\|CRISPRCasFinder,CRT	3088835-3088865	31	NZ_CP024832	Escherichia coli strain CREC-532 plasmid pCREC-532_2, complete sequence	33830-33860	9	0.71
NZ_CP045154_5	5.3\|3088835\|31\|NZ_CP045154\|CRISPRCasFinder,CRT	3088835-3088865	31	NZ_CP024817	Escherichia coli strain CREC-629 plasmid pCREC-629_2, complete sequence	62769-62799	9	0.71
NZ_CP045154_5	5.3\|3088835\|31\|NZ_CP045154\|CRISPRCasFinder,CRT	3088835-3088865	31	NZ_CP029117	Escherichia coli strain AR435 plasmid unnamed4	15616-15646	9	0.71
NZ_CP045154_5	5.3\|3088835\|31\|NZ_CP045154\|CRISPRCasFinder,CRT	3088835-3088865	31	NZ_CP029117	Escherichia coli strain AR435 plasmid unnamed4	112580-112610	9	0.71
NZ_CP045154_5	5.3\|3088835\|31\|NZ_CP045154\|CRISPRCasFinder,CRT	3088835-3088865	31	NZ_CP023961	Escherichia coli strain FDAARGOS_448 plasmid unnamed2, complete sequence	16858-16888	9	0.71
NZ_CP045154_5	5.3\|3088835\|31\|NZ_CP045154\|CRISPRCasFinder,CRT	3088835-3088865	31	AP023233	Escherichia coli YJ4 plasmid pYJ4-b DNA, complete genome	47570-47600	9	0.71
NZ_CP045154_5	5.3\|3088835\|31\|NZ_CP045154\|CRISPRCasFinder,CRT	3088835-3088865	31	NZ_CP019075	Escherichia coli strain CRE1493 plasmid p1493-4, complete sequence	16520-16550	9	0.71
NZ_CP045154_5	5.3\|3088835\|31\|NZ_CP045154\|CRISPRCasFinder,CRT	3088835-3088865	31	NZ_CP015837	Escherichia coli strain MS6198 plasmid pMS6198C, complete sequence	3287-3317	9	0.71
NZ_CP045154_5	5.3\|3088835\|31\|NZ_CP045154\|CRISPRCasFinder,CRT	3088835-3088865	31	NZ_CP011063	Escherichia coli str. Sanji plasmid pSJ_98, complete sequence	37637-37667	9	0.71
NZ_CP045154_5	5.3\|3088835\|31\|NZ_CP045154\|CRISPRCasFinder,CRT	3088835-3088865	31	NZ_CP040920	Escherichia coli strain FC853_EC plasmid p853EC1, complete sequence	33436-33466	9	0.71
NZ_CP045154_5	5.3\|3088835\|31\|NZ_CP045154\|CRISPRCasFinder,CRT	3088835-3088865	31	AP023222	Escherichia coli M505 plasmid pM505-b DNA, complete genome	93735-93765	9	0.71
NZ_CP045154_5	5.4\|3088776\|30\|NZ_CP045154\|PILER-CR	3088776-3088805	30	AP014500	Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S32-C79, * SEQUENCING IN PROGRESS *, 2 ordered pieces	26487-26516	9	0.7
NZ_CP045154_2	2.3\|1429901\|35\|NZ_CP045154\|PILER-CR	1429901-1429935	35	NZ_CP040366	Bacillus flexus isolate 1-2-1 plasmid punnamed3, complete sequence	923-957	10	0.714

1. spacer 2.8|1429964|32|NZ_CP045154|CRISPRCasFinder,CRT matches to MT374852 (Yersinia phage vB_YpM_3, complete genome) position: , mismatch: 0, identity: 1.0

agactgatgcaagatggcggtatgcgtacaga	CRISPR spacer
agactgatgcaagatggcggtatgcgtacaga	Protospacer
********************************

2. spacer 2.4|1429962|34|NZ_CP045154|PILER-CR matches to MT374852 (Yersinia phage vB_YpM_3, complete genome) position: , mismatch: 1, identity: 0.971

aaagactgatgcaagatggcggtatgcgtacaga	CRISPR spacer
caagactgatgcaagatggcggtatgcgtacaga	Protospacer
 *********************************

3. spacer 4.2|2112174|32|NZ_CP045154|PILER-CR,CRISPRCasFinder,CRT matches to MH616963 (CrAssphage sp. isolate ctbg_1, complete genome) position: , mismatch: 7, identity: 0.781

atttattaaagatgctgacaaaaagaacttaa	CRISPR spacer
aattataaaagatgctgataaaaagattatta	Protospacer
* **** ***********.******* . * *

4. spacer 5.1|3088715|31|NZ_CP045154|CRISPRCasFinder,CRT matches to CP049262 (Cronobacter sakazakii strain CS-09 plasmid pCsaCS09b, complete sequence) position: , mismatch: 7, identity: 0.774

tcaggggactggcgaacaatgtctttcatga	CRISPR spacer
acgtcgcgctggcgaacaatctctttcatga	Protospacer
 *.  * .************ **********

5. spacer 5.3|3088835|31|NZ_CP045154|CRISPRCasFinder,CRT matches to NC_021534 (Vibrio phage pYD38-A genomic sequence) position: , mismatch: 7, identity: 0.774

attatctgaatggcattttctttggcgcaga	CRISPR spacer
attacctgaatggcatttgctttatgcctga	Protospacer
****.************* ****.   * **

6. spacer 5.3|3088835|31|NZ_CP045154|CRISPRCasFinder,CRT matches to JF974294 (Aeromonas phage pIS4-A genomic sequence) position: , mismatch: 7, identity: 0.774

attatctgaatggcattttctttggcgcaga	CRISPR spacer
attacctgaatggcatttgctttatgcctga	Protospacer
****.************* ****.   * **

7. spacer 5.4|3088776|30|NZ_CP045154|PILER-CR matches to NZ_CP031943 (Nostoc sphaeroides strain Kutzing En plasmid p2, complete sequence) position: , mismatch: 7, identity: 0.767

aaaaggtaagatgggcaagcttctagtagt	CRISPR spacer
tatgagaaagatgggcaagcttttagtggt	Protospacer
 * ..* ***************.****.**

8. spacer 5.5|3088836|30|NZ_CP045154|PILER-CR matches to NZ_CP013487 (Vibrio alginolyticus strain ATCC 33787 plasmid pMBL287, complete sequence) position: , mismatch: 7, identity: 0.767

ttatctgaatggcattttctttggcgcaga	CRISPR spacer
cttgttcagtggcattttctttggcacaga	Protospacer
.*  .* *.****************.****

9. spacer 4.2|2112174|32|NZ_CP045154|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP010358 (Acinetobacter johnsonii XBB1 plasmid pXBB1-8, complete sequence) position: , mismatch: 8, identity: 0.75

atttattaaagatgctgacaaaaagaacttaa	CRISPR spacer
atttattaatgatgctgacgaaaatatggcac	Protospacer
********* *********.**** *   .*

10. spacer 4.2|2112174|32|NZ_CP045154|PILER-CR,CRISPRCasFinder,CRT matches to NC_019694 (Oscillatoria acuminata PCC 6304 plasmid pOSCIL6304.02, complete sequence) position: , mismatch: 8, identity: 0.75

atttattaaagatgctgacaaaaagaacttaa	CRISPR spacer
atttattaaagaagctgccaaaagagcatcaa	Protospacer
************ **** *****...  *.**

11. spacer 5.2|3088775|31|NZ_CP045154|CRISPRCasFinder,CRT matches to NZ_CP031943 (Nostoc sphaeroides strain Kutzing En plasmid p2, complete sequence) position: , mismatch: 8, identity: 0.742

gaaaaggtaagatgggcaagcttctagtagt	CRISPR spacer
ttatgagaaagatgggcaagcttttagtggt	Protospacer
  * ..* ***************.****.**

12. spacer 2.7|1429903|33|NZ_CP045154|CRISPRCasFinder,CRT matches to NZ_CP040366 (Bacillus flexus isolate 1-2-1 plasmid punnamed3, complete sequence) position: , mismatch: 9, identity: 0.727

ccgaaatcatcagatgtaattaagatttttgct	CRISPR spacer
aatggattatcagatgtaattaagtttttttcc	Protospacer
   ..**.**************** ***** *.

13. spacer 4.2|2112174|32|NZ_CP045154|PILER-CR,CRISPRCasFinder,CRT matches to MT774386 (CrAssphage cr110_1, complete genome) position: , mismatch: 9, identity: 0.719

atttattaaagatgctgacaaaaagaacttaa	CRISPR spacer
tgctattgaagatgctgataaaaagaaacttg	Protospacer
  .****.**********.******** .* .

14. spacer 4.2|2112174|32|NZ_CP045154|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP028934 (Campylobacter jejuni strain FORC_083 plasmid pFORC_083_2, complete sequence) position: , mismatch: 9, identity: 0.719

atttattaaagatgctgacaaaaagaacttaa	CRISPR spacer
gcacattacagacgctgacaaaaagaaagtta	Protospacer
.. .**** ***.**************  * *

15. spacer 5.3|3088835|31|NZ_CP045154|CRISPRCasFinder,CRT matches to MF679145 (Escherichia coli plasmid pBJ114-96, complete sequence) position: , mismatch: 9, identity: 0.71

attatctgaatggcattttctttggcgcaga	CRISPR spacer
attatctgattggcagtttctttaactgttt	Protospacer
********* ***** *******..*

16. spacer 5.3|3088835|31|NZ_CP045154|CRISPRCasFinder,CRT matches to NZ_KP453775 (Klebsiella pneumoniae strain ST11 plasmid pKP12226, complete sequence) position: , mismatch: 9, identity: 0.71

attatctgaatggcattttctttggcgcaga	CRISPR spacer
attatctgattggcagtttctttaactgttt	Protospacer
********* ***** *******..*

17. spacer 5.3|3088835|31|NZ_CP045154|CRISPRCasFinder,CRT matches to NZ_CP021340 (Escherichia coli strain 95NR1 plasmid p95NR1A, complete sequence) position: , mismatch: 9, identity: 0.71

attatctgaatggcattttctttggcgcaga	CRISPR spacer
attatctgattggcagtttctttaactgttt	Protospacer
********* ***** *******..*

18. spacer 5.3|3088835|31|NZ_CP045154|CRISPRCasFinder,CRT matches to NZ_CP021336 (Escherichia coli strain 95JB1 plasmid p95JB1A, complete sequence) position: , mismatch: 9, identity: 0.71

attatctgaatggcattttctttggcgcaga	CRISPR spacer
attatctgattggcagtttctttaactgttt	Protospacer
********* ***** *******..*

19. spacer 5.3|3088835|31|NZ_CP045154|CRISPRCasFinder,CRT matches to NZ_CP024832 (Escherichia coli strain CREC-532 plasmid pCREC-532_2, complete sequence) position: , mismatch: 9, identity: 0.71

attatctgaatggcattttctttggcgcaga	CRISPR spacer
attatctgattggcagtttctttaactgttt	Protospacer
********* ***** *******..*

20. spacer 5.3|3088835|31|NZ_CP045154|CRISPRCasFinder,CRT matches to NZ_CP024817 (Escherichia coli strain CREC-629 plasmid pCREC-629_2, complete sequence) position: , mismatch: 9, identity: 0.71

attatctgaatggcattttctttggcgcaga	CRISPR spacer
attatctgattggcagtttctttaactgttt	Protospacer
********* ***** *******..*

21. spacer 5.3|3088835|31|NZ_CP045154|CRISPRCasFinder,CRT matches to NZ_CP029117 (Escherichia coli strain AR435 plasmid unnamed4) position: , mismatch: 9, identity: 0.71

attatctgaatggcattttctttggcgcaga	CRISPR spacer
attatctgattggcagtttctttaactgttt	Protospacer
********* ***** *******..*

22. spacer 5.3|3088835|31|NZ_CP045154|CRISPRCasFinder,CRT matches to NZ_CP029117 (Escherichia coli strain AR435 plasmid unnamed4) position: , mismatch: 9, identity: 0.71

attatctgaatggcattttctttggcgcaga	CRISPR spacer
attatctgattggcagtttctttaactgttt	Protospacer
********* ***** *******..*

23. spacer 5.3|3088835|31|NZ_CP045154|CRISPRCasFinder,CRT matches to NZ_CP023961 (Escherichia coli strain FDAARGOS_448 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.71

attatctgaatggcattttctttggcgcaga	CRISPR spacer
attatctgattggcagtttctttaactgttt	Protospacer
********* ***** *******..*

24. spacer 5.3|3088835|31|NZ_CP045154|CRISPRCasFinder,CRT matches to AP023233 (Escherichia coli YJ4 plasmid pYJ4-b DNA, complete genome) position: , mismatch: 9, identity: 0.71

attatctgaatggcattttctttggcgcaga	CRISPR spacer
attatctgattggcagtttctttaactgttt	Protospacer
********* ***** *******..*

25. spacer 5.3|3088835|31|NZ_CP045154|CRISPRCasFinder,CRT matches to NZ_CP019075 (Escherichia coli strain CRE1493 plasmid p1493-4, complete sequence) position: , mismatch: 9, identity: 0.71

attatctgaatggcattttctttggcgcaga	CRISPR spacer
attatctgattggcagtttctttaactgttt	Protospacer
********* ***** *******..*

26. spacer 5.3|3088835|31|NZ_CP045154|CRISPRCasFinder,CRT matches to NZ_CP015837 (Escherichia coli strain MS6198 plasmid pMS6198C, complete sequence) position: , mismatch: 9, identity: 0.71

attatctgaatggcattttctttggcgcaga	CRISPR spacer
attatctgattggcagtttctttaactgttt	Protospacer
********* ***** *******..*

27. spacer 5.3|3088835|31|NZ_CP045154|CRISPRCasFinder,CRT matches to NZ_CP011063 (Escherichia coli str. Sanji plasmid pSJ_98, complete sequence) position: , mismatch: 9, identity: 0.71

attatctgaatggcattttctttggcgcaga	CRISPR spacer
attatctgattggcagtttctttaactgttt	Protospacer
********* ***** *******..*

28. spacer 5.3|3088835|31|NZ_CP045154|CRISPRCasFinder,CRT matches to NZ_CP040920 (Escherichia coli strain FC853_EC plasmid p853EC1, complete sequence) position: , mismatch: 9, identity: 0.71

attatctgaatggcattttctttggcgcaga	CRISPR spacer
attatctgattggcagtttctttaactgttt	Protospacer
********* ***** *******..*

29. spacer 5.3|3088835|31|NZ_CP045154|CRISPRCasFinder,CRT matches to AP023222 (Escherichia coli M505 plasmid pM505-b DNA, complete genome) position: , mismatch: 9, identity: 0.71

attatctgaatggcattttctttggcgcaga	CRISPR spacer
attatctgattggcagtttctttaactgttt	Protospacer
********* ***** *******..*

30. spacer 5.4|3088776|30|NZ_CP045154|PILER-CR matches to AP014500 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S32-C79, *** SEQUENCING IN PROGRESS ***, 2 ordered pieces) position: , mismatch: 9, identity: 0.7

aaaaggtaagatgggcaagcttctagtagt	CRISPR spacer
gttgtagaagatgtgcaagcttctagtaat	Protospacer
.  . . ****** **************.*

31. spacer 2.3|1429901|35|NZ_CP045154|PILER-CR matches to NZ_CP040366 (Bacillus flexus isolate 1-2-1 plasmid punnamed3, complete sequence) position: , mismatch: 10, identity: 0.714

aaccgaaatcatcagatgtaattaagatttttgct	CRISPR spacer
ataatggattatcagatgtaattaagtttttttcc	Protospacer
*    ..**.**************** ***** *.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

438042 : 510633

Escherichia_phage(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000255944.1\|438042_439065_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_001297096.1\|439064_439844_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_002211540.1\|439882_440218_+	deoxyribonuclease	NA	NA	NA	NA
WP_002211541.1\|440232_441255_+	porphobilinogen synthase	NA	NA	NA	NA
WP_002211542.1\|441364_441853_-	transcription/translation regulatory transformer protein RfaH	NA	NA	NA	NA
WP_002215917.1\|442100_443597_+	4-hydroxy-3-polyprenylbenzoate decarboxylase	NA	NA	NA	NA
WP_002215918.1\|443651_444353_+	NAD(P)H-flavin reductase	NA	NA	NA	NA
WP_002211545.1\|444512_445676_-	acetyl-CoA C-acyltransferase FadA	NA	NA	NA	NA
WP_002211546.1\|445687_447877_-	fatty acid oxidation complex subunit alpha FadB	NA	NA	NA	NA
WP_002211547.1\|448203_449535_+	Xaa-Pro dipeptidase	NA	NA	NA	NA
WP_002211548.1\|449534_449744_+	hypothetical protein	NA	NA	NA	NA
WP_002213759.1\|449848_450307_+\|transposase	IS200/IS605-like element IS1541A family transposase	NA	NA	NA	NA
WP_002211550.1\|450895_452347_+	Trk system potassium transporter TrkH	NA	NA	NA	NA
WP_002215920.1\|452368_452902_+	menaquinone-dependent protoporphyrinogen IX dehydrogenase	NA	NA	NA	NA
WP_002218887.1\|453185_453371_-	hypothetical protein	NA	NA	NA	NA
WP_161992928.1\|455666_455828_-	hypothetical protein	A0A140XBD7	Dickeya_phage	2.3e-21	88.7
WP_002212288.1\|459038_460076_+	UDP-N-acetylmuramate dehydrogenase	NA	NA	NA	NA
WP_002212289.1\|460072_461032_+	bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA	NA	NA	NA	NA
WP_002212290.1\|461066_462017_-	type I pantothenate kinase	A0A1B1ISL9	uncultured_Mediterranean_phage	8.7e-28	31.2
WP_002217850.1\|462227_462779_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000255944.1\|462868_463891_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_001297096.1\|463890_464670_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_002210669.1\|465726_466911_+	elongation factor Tu	A0A2K9L516	Tupanvirus	2.0e-13	26.9
WP_002210670.1\|467161_467545_+	preprotein translocase subunit SecE	NA	NA	NA	NA
WP_002210671.1\|467546_468092_+	transcription termination/antitermination protein NusG	A0A291AUS6	Sinorhizobium_phage	5.9e-13	28.3
WP_002210672.1\|468282_468711_+	50S ribosomal protein L11	NA	NA	NA	NA
WP_002210673.1\|468714_469419_+	50S ribosomal protein L1	NA	NA	NA	NA
WP_002210674.1\|469783_470281_+	50S ribosomal protein L10	NA	NA	NA	NA
WP_002210675.1\|470347_470716_+	50S ribosomal protein L7/L12	NA	NA	NA	NA
WP_002210676.1\|471058_475087_+	DNA-directed RNA polymerase subunit beta	A0A0N9R0J7	Chrysochromulina_ericina_virus	1.2e-22	29.0
WP_002210677.1\|475215_479436_+	DNA-directed RNA polymerase subunit beta'	A0A2I7QNZ7	Vibrio_phage	8.5e-67	27.0
WP_002213775.1\|479562_480021_-\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002210678.1\|480452_481583_-	2-iminoacetate synthase ThiH	NA	NA	NA	NA
WP_002228257.1\|481575_482391_-	thiazole synthase	NA	NA	NA	NA
WP_002217275.1\|482392_482608_-	sulfur carrier protein ThiS	NA	NA	NA	NA
WP_002210680.1\|482604_483402_-	HesA/MoeB/ThiF family protein	A0A1V0SAV8	Catovirus	1.6e-11	27.8
WP_002210681.1\|483391_484066_-	thiamine phosphate synthase	NA	NA	NA	NA
WP_002210682.1\|484052_486098_-	phosphomethylpyrimidine synthase ThiC	NA	NA	NA	NA
WP_002210683.1\|486473_486983_-	sigma D regulator	NA	NA	NA	NA
WP_002210684.1\|487079_487862_+	NAD(+) diphosphatase	NA	NA	NA	NA
WP_002210685.1\|487954_488740_+	hypothetical protein	NA	NA	NA	NA
WP_002210686.1\|488858_489926_+	uroporphyrinogen decarboxylase	NA	NA	NA	NA
WP_002210687.1\|489955_490696_+	deoxyribonuclease V	NA	NA	NA	NA
WP_002210688.1\|490741_491332_+	YjaG family protein	NA	NA	NA	NA
WP_002210689.1\|491520_491796_+	DNA-binding protein HU-alpha	A7KV42	Bacillus_phage	3.6e-19	55.6
WP_002355296.1\|491845_492499_+	DUF1481 domain-containing protein	NA	NA	NA	NA
WP_002210691.1\|492646_493933_-	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_002210692.1\|493992_495582_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	2.2e-68	49.4
WP_002218887.1\|496049_496235_-	hypothetical protein	NA	NA	NA	NA
WP_161992928.1\|498530_498692_-	hypothetical protein	A0A140XBD7	Dickeya_phage	2.3e-21	88.7
WP_002220999.1\|501941_503150_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_002217538.1\|503207_503738_-	molybdopterin-guanine dinucleotide biosynthesis protein B	NA	NA	NA	NA
WP_002213171.1\|503737_504325_-	molybdenum cofactor guanylyltransferase MobA	NA	NA	NA	NA
WP_002213170.1\|504478_504748_+	YihD family protein	NA	NA	NA	NA
WP_002213169.1\|504838_505825_+	serine/threonine protein kinase	NA	NA	NA	NA
WP_002213168.1\|505852_506476_+	thiol:disulfide interchange protein DsbA	NA	NA	NA	NA
WP_002213164.1\|506967_509766_+	DNA polymerase I	A0A218MKQ4	uncultured_virus	2.7e-69	32.8
WP_002213759.1\|510174_510633_+\|transposase	IS200/IS605-like element IS1541A family transposase	NA	NA	NA	NA

DBSCAN-SWA_2

627733 : 690092

Bodo_saltans_virus(16.67%)

plate,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002210509.1\|627733_630550_+\|tRNA	isoleucine--tRNA ligase	A0A2H4UVG0	Bodo_saltans_virus	1.0e-63	26.1
WP_002210508.1\|630549_631059_+	lipoprotein signal peptidase	NA	NA	NA	NA
WP_002228112.1\|631126_631585_+	FKBP-type peptidyl-prolyl cis-trans isomerase	NA	NA	NA	NA
WP_002210506.1\|631565_632519_+	4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NA	NA	NA	NA
WP_002213775.1\|632900_633359_+\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002210453.1\|633505_635068_+	2-isopropylmalate synthase	NA	NA	NA	NA
WP_002210454.1\|635070_636162_+	3-isopropylmalate dehydrogenase	NA	NA	NA	NA
WP_002210455.1\|636163_637594_+	3-isopropylmalate dehydratase large subunit	NA	NA	NA	NA
WP_002210456.1\|637608_638211_+	3-isopropylmalate dehydratase small subunit	NA	NA	NA	NA
WP_002224086.1\|638451_639633_-	MFS transporter	NA	NA	NA	NA
WP_002210461.1\|640296_641958_+	HTH-type transcriptional regulator SgrR	NA	NA	NA	NA
WP_002214274.1\|642897_643890_+	thiamine ABC transporter substrate binding subunit	NA	NA	NA	NA
WP_002214276.1\|643865_645473_+	thiamine/thiamine pyrophosphate ABC transporter permease ThiP	NA	NA	NA	NA
WP_002210464.1\|645459_646170_+	thiamine ABC transporter ATP-binding protein ThiQ	G3M9Y6	Bacillus_virus	1.0e-20	34.1
WP_002210465.1\|646238_647006_-	DedA family protein	NA	NA	NA	NA
WP_002210466.1\|647201_649571_+	DNA polymerase II	A0A0P0YM26	Yellowstone_lake_phycodnavirus	1.5e-31	25.5
WP_002220588.1\|650031_652938_+	RNA polymerase-associated protein RapA	A0A1B1IUI1	uncultured_Mediterranean_phage	3.0e-23	37.6
WP_002210468.1\|653193_653547_-	hypothetical protein	NA	NA	NA	NA
WP_002210469.1\|657071_658682_-	OmpA family protein	NA	NA	NA	NA
WP_002210470.1\|658678_660034_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_002210471.1\|660153_660645_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_002214737.1\|660637_661003_-	DUF4150 domain-containing protein	NA	NA	NA	NA
WP_002210473.1\|661008_661626_-	DUF3540 domain-containing protein	NA	NA	NA	NA
WP_002214739.1\|661618_662722_-	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_002224087.1\|662747_664967_-	DUF2169 domain-containing protein	NA	NA	NA	NA
WP_002210474.1\|664979_667328_-	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	2.1e-14	32.9
WP_002210475.1\|667431_670020_-	type VI secretion system ATPase TssH	A0A248SJW6	Salicola_phage	1.9e-77	28.7
WP_002210476.1\|670037_671021_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_002210477.1\|671013_672858_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_002210478.1\|672890_673334_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_002210479.1\|673407_673926_-	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_002210480.1\|674088_675591_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_002210481.1\|675599_676160_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_002210482.1\|676170_677184_-	ImpA family type VI secretion system protein	NA	NA	NA	NA
WP_002214747.1\|677513_678257_+	DUF2285 domain-containing protein	NA	NA	NA	NA
WP_002210485.1\|679479_680100_+\|tRNA	bifunctional tRNA pseudouridine(32) synthase/23S rRNA pseudouridine(746) synthase RluA	NA	NA	NA	NA
WP_002210486.1\|680397_681231_-	co-chaperone DjlA	NA	NA	NA	NA
WP_002228111.1\|681415_683758_+	LPS assembly protein LptD	NA	NA	NA	NA
WP_002210488.1\|683825_685130_+	peptidylprolyl isomerase SurA	NA	NA	NA	NA
WP_002210489.1\|685113_686109_+	4-hydroxythreonine-4-phosphate dehydrogenase PdxA	NA	NA	NA	NA
WP_002210490.1\|686101_686920_+	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	NA	NA	NA	NA
WP_002210491.1\|686933_687311_+	Co2+/Mg2+ efflux protein ApaG	NA	NA	NA	NA
WP_002210492.1\|687327_688197_+	bis(5'-nucleosyl)-tetraphosphatase (symmetrical)	NA	NA	NA	NA
WP_002210493.1\|688286_688751_-	DUF3757 domain-containing protein	NA	NA	NA	NA
WP_071525509.1\|688877_689192_-	DUF3757 domain-containing protein	NA	NA	NA	NA
WP_002213775.1\|689633_690092_-\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA

DBSCAN-SWA_3

1222713 : 1267349

uncultured_Mediterranean_phage(23.08%)

tRNA,transposase,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002213775.1\|1222713_1223172_-\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002208705.1\|1223357_1224962_-	chitin-binding domain protein	Q9J8B0	Spodoptera_exigua_multiple_nucleopolyhedrovirus	2.3e-20	31.0
WP_002216043.1\|1225158_1225464_-\|holin	holin	A0A286N2Q5	Klebsiella_phage	2.0e-10	46.2
WP_002208704.1\|1225890_1226349_+	xanthine phosphoribosyltransferase	NA	NA	NA	NA
WP_002208703.1\|1226475_1227723_+	esterase FrsA	NA	NA	NA	NA
WP_002208702.1\|1227782_1228184_+	sigma factor-binding protein Crl	NA	NA	NA	NA
WP_002208701.1\|1228360_1229464_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.5e-60	43.6
WP_002208700.1\|1229473_1230733_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	1.0e-92	45.4
WP_002213775.1\|1230995_1231454_+\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002264519.1\|1231779_1232529_+	flagellar brake protein	NA	NA	NA	NA
WP_002208698.1\|1232726_1232981_+	hypothetical protein	NA	NA	NA	NA
WP_099156357.1\|1233106_1233748_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_002208694.1\|1234477_1235035_+	methyltransferase	NA	NA	NA	NA
WP_002208693.1\|1235281_1235806_+	shikimate kinase AroL	NA	NA	NA	NA
WP_002208692.1\|1236295_1236583_+	pyrimidine/purine nucleoside phosphorylase	NA	NA	NA	NA
WP_042468846.1\|1236818_1237730_-	recombination-associated protein RdgC	S4TWL4	Salmonella_phage	7.4e-101	65.9
WP_000255944.1\|1237792_1238815_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_001297096.1\|1238814_1239594_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_002208690.1\|1240022_1240937_+	fructokinase	NA	NA	NA	NA
WP_002223265.1\|1241538_1245228_-	AAA family ATPase	G3MAB6	Bacillus_virus	2.2e-10	26.1
WP_002208687.1\|1245224_1246469_-	exonuclease subunit SbcD	NA	NA	NA	NA
WP_002208685.1\|1246736_1247426_+	phosphate response regulator transcription factor PhoB	W8CYM9	Bacillus_phage	1.7e-36	37.1
WP_002208684.1\|1247450_1248767_+	phosphate regulon sensor histidine kinase PhoR	W8CYF6	Bacillus_phage	7.1e-28	29.2
WP_002215524.1\|1248788_1249853_+	phosphate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002208680.1\|1250326_1251646_+	branched-chain amino acid transport system II carrier protein	NA	NA	NA	NA
WP_002223269.1\|1251721_1253113_+	proline-specific permease ProY	NA	NA	NA	NA
WP_002213775.1\|1253330_1253789_+\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002208678.1\|1254384_1256214_+	maltodextrin glucosidase	NA	NA	NA	NA
WP_002222306.1\|1256210_1256393_-	hypothetical protein	NA	NA	NA	NA
WP_002208677.1\|1256368_1257049_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_002208675.1\|1259410_1260013_-	peroxiredoxin C	NA	NA	NA	NA
WP_002216927.1\|1260311_1260893_-	ACP phosphodiesterase	NA	NA	NA	NA
WP_002208673.1\|1261095_1262166_+\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_002208672.1\|1262258_1263383_+\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	3.2e-90	45.8
WP_002208671.1\|1263494_1263830_+	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	6.4e-10	35.6
WP_002223272.1\|1263857_1265705_+	protein translocase subunit SecD	NA	NA	NA	NA
WP_002208669.1\|1265715_1266684_+	protein translocase subunit SecF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.9e-46	39.7
WP_002213759.1\|1266890_1267349_+\|transposase	IS200/IS605-like element IS1541A family transposase	NA	NA	NA	NA

DBSCAN-SWA_4

1367590 : 1422345

uncultured_virus(20.0%)

integrase,tRNA,transposase,protease

attL 1362928:1362946|attR 1438956:1438974

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1362928:1362946	attL	NA	NA	NA	NA
WP_002208581.1\|1367590_1368070_-\|tRNA	Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK	NA	NA	NA	NA
WP_002208580.1\|1368333_1369143_-	hypothetical protein	NA	NA	NA	NA
WP_002223301.1\|1369663_1372549_-	copper-exporting P-type ATPase CopA	A0A218MNH6	uncultured_virus	1.0e-111	36.8
WP_002208578.1\|1372755_1373175_+	Cu(I)-responsive transcriptional regulator	NA	NA	NA	NA
WP_002208577.1\|1373283_1373733_-	NfeD family protein	NA	NA	NA	NA
WP_002208576.1\|1373735_1374650_-	SPFH/Band 7/PHB domain protein	NA	NA	NA	NA
WP_002208575.1\|1374844_1375714_-	co-chaperone YbbN	NA	NA	NA	NA
WP_002208574.1\|1375790_1376567_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_002208573.1\|1376953_1377589_-\|protease	multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1	NA	NA	NA	NA
WP_002208572.1\|1377559_1378246_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.6e-31	34.2
WP_002208571.1\|1378242_1380672_+	ABC transporter permease	NA	NA	NA	NA
WP_002208570.1\|1380715_1381780_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_002208569.1\|1381776_1382301_-	5-(carboxyamino)imidazole ribonucleotide mutase	NA	NA	NA	NA
WP_002208568.1\|1382596_1383319_-	UDP-2,3-diacylglucosamine diphosphatase	NA	NA	NA	NA
WP_002208567.1\|1383329_1383824_-	peptidylprolyl isomerase B	NA	NA	NA	NA
WP_002222677.1\|1384034_1385420_+\|tRNA	cysteine--tRNA ligase	A0A0G2Y344	Acanthamoeba_polyphaga_mimivirus	2.2e-40	28.5
WP_002213775.1\|1385766_1386225_+\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002209775.1\|1386371_1386584_-	ribosome-associated protein YbcJ	NA	NA	NA	NA
WP_002209774.1\|1386598_1387465_-	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	2.2e-30	34.1
WP_002215270.1\|1387819_1388002_-	AlpA family phage regulatory protein	NA	NA	NA	NA
WP_002215268.1\|1388260_1388461_-	hypothetical protein	NA	NA	NA	NA
WP_002228356.1\|1388574_1389072_-	hypothetical protein	NA	NA	NA	NA
WP_002215266.1\|1389207_1389546_-	hypothetical protein	NA	NA	NA	NA
WP_079866998.1\|1389628_1389907_-\|integrase	tyrosine-type recombinase/integrase	A0A192Y6Q1	Salmonella_phage	4.2e-31	73.5
WP_002354559.1\|1390118_1390325_+	hypothetical protein	NA	NA	NA	NA
WP_002209770.1\|1390724_1391327_+	CDP-alcohol phosphatidyltransferase family protein	NA	NA	NA	NA
WP_002209769.1\|1391319_1392249_+	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_002209768.1\|1392258_1392891_+	1-acyl-sn-glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
WP_002209767.1\|1392887_1394651_+	bifunctional alpha/beta hydrolase/class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_002209766.1\|1394643_1395963_+	phosphatase PAP2/dual specificity phosphatase family protein	NA	NA	NA	NA
WP_002209765.1\|1395944_1396346_+	hypothetical protein	NA	NA	NA	NA
WP_002215253.1\|1396442_1396748_+	hypothetical protein	NA	NA	NA	NA
WP_001297096.1\|1397114_1397894_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_000255944.1\|1397893_1398916_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_002209764.1\|1399009_1399903_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002209763.1\|1399957_1400947_-	aldo/keto reductase	NA	NA	NA	NA
WP_002209762.1\|1400972_1401824_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	1.2e-49	41.1
WP_002209759.1\|1402296_1403925_+	hypothetical protein	NA	NA	NA	NA
WP_002209758.1\|1404003_1406385_-	glycosyl hydrolase	NA	NA	NA	NA
WP_002209757.1\|1406543_1407074_-	GDYXXLXY domain-containing protein	NA	NA	NA	NA
WP_002209756.1\|1407066_1409274_-	DUF4401 domain-containing protein	NA	NA	NA	NA
WP_002209743.1\|1409725_1410934_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_002209753.1\|1411335_1411917_-	hypothetical protein	NA	NA	NA	NA
WP_002224869.1\|1412205_1412328_-	hypothetical protein	NA	NA	NA	NA
WP_002209752.1\|1412451_1414368_-	autotransporter adhesin YapC	NA	NA	NA	NA
WP_002209751.1\|1415176_1415416_+	hypothetical protein	NA	NA	NA	NA
WP_002227852.1\|1415454_1415706_+	hypothetical protein	NA	NA	NA	NA
WP_002209749.1\|1415729_1416302_+	Hcp family type VI secretion system effector	NA	NA	NA	NA
WP_002209748.1\|1416313_1416715_-	DUF1240 domain-containing protein	NA	NA	NA	NA
WP_002209746.1\|1416947_1417349_-	DUF1240 domain-containing protein	NA	NA	NA	NA
WP_002216002.1\|1417616_1418198_-	hypothetical protein	NA	NA	NA	NA
WP_002209745.1\|1418870_1419116_+	transcriptional regulator	A0A2I7S995	Vibrio_phage	7.2e-19	64.2
WP_138921619.1\|1419328_1421641_-	penicillin-binding protein 1C	NA	NA	NA	NA
WP_002213775.1\|1421886_1422345_+\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
1438956:1438974	attR	NA	NA	NA	NA

DBSCAN-SWA_5

1704423 : 1749782

Pseudomonas_phage(25.0%)

transposase,coat,plate,tail,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002210815.1\|1704423_1704933_-\|protease	serine protease inhibitor ecotin	NA	NA	NA	NA
WP_002210816.1\|1704967_1705225_-	2Fe-2S ferredoxin-like protein	G9IAA2	Pseudomonas_phage	4.0e-20	54.9
WP_002210817.1\|1705228_1706359_-	ribonucleotide-diphosphate reductase subunit beta	G9IAA3	Pseudomonas_phage	7.6e-172	78.6
WP_002210818.1\|1706521_1708810_-	ribonucleoside-diphosphate reductase subunit alpha	I3UMG3	Colwellia_phage	1.1e-286	64.9
WP_002210820.1\|1709303_1710032_-	bifunctional 3-demethylubiquinone 3-O-methyltransferase/2-octaprenyl-6-hydroxy phenol methylase	NA	NA	NA	NA
WP_002210821.1\|1710293_1712969_+	DNA topoisomerase (ATP-hydrolyzing) subunit A	G3M9Z5	Bacillus_virus	4.0e-102	34.4
WP_080071931.1\|1713156_1716030_+	two-component system sensor histidine kinase RcsC	A0A1V0SGX0	Hokovirus	3.8e-42	28.3
WP_002210824.1\|1716097_1716751_-	transcriptional regulator RcsB	NA	NA	NA	NA
WP_002216094.1\|1716753_1717326_-	histidine phosphotransferase	NA	NA	NA	NA
WP_002216093.1\|1717493_1719446_-	phosphotransferase RcsD	NA	NA	NA	NA
WP_002210825.1\|1719469_1720624_-	MFS transporter	NA	NA	NA	NA
WP_002210826.1\|1721726_1722842_+	porin OmpC	Q1MVN1	Enterobacteria_phage	9.6e-111	57.6
WP_002213759.1\|1723043_1723502_+\|transposase	IS200/IS605-like element IS1541A family transposase	NA	NA	NA	NA
WP_002228026.1\|1724291_1725458_-	D-alanyl-D-alanine- carboxypeptidase/endopeptidase AmpH	NA	NA	NA	NA
WP_002208870.1\|1725732_1727259_-	MFS transporter	NA	NA	NA	NA
WP_002208869.1\|1727635_1728664_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_002208868.1\|1728737_1730525_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	4.0e-10	63.5
WP_002208867.1\|1730946_1731882_-	omptin family outer membrane beta-barrel protein YcoA	NA	NA	NA	NA
WP_002208866.1\|1732053_1732296_-	DinI family protein	K7PKR6	Enterobacteria_phage	6.9e-22	65.0
WP_002208864.1\|1732501_1733224_-	LexA family transcriptional regulator	F1C599	Cronobacter_phage	2.2e-63	51.9
WP_002215470.1\|1733497_1733977_+	antitermination protein Q	S5M7R9	Escherichia_phage	2.3e-37	61.0
WP_002208862.1\|1734187_1735492_+	four-carbon acid sugar kinase family protein	A0A077SLJ7	Escherichia_phage	1.7e-90	46.0
WP_002208861.1\|1736200_1737013_+	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
WP_002208860.1\|1736988_1737783_+	hydroxypyruvate isomerase family protein	NA	NA	NA	NA
WP_002208859.1\|1738413_1738704_+	hypothetical protein	H6WRZ3	Salmonella_phage	7.7e-12	46.3
WP_002208858.1\|1738749_1739367_+	ATP-binding protein	NA	NA	NA	NA
WP_002208857.1\|1739371_1739566_+	DUF2635 domain-containing protein	B5TK66	Pseudomonas_phage	3.5e-08	60.4
WP_002208856.1\|1739562_1741071_+\|tail	tail protein	B5TK67	Pseudomonas_phage	2.4e-104	44.2
WP_002208855.1\|1741092_1741461_+\|tail	phage tail protein	NA	NA	NA	NA
WP_002208854.1\|1741462_1741762_+\|tail	phage tail assembly protein	NA	NA	NA	NA
WP_002208853.1\|1741882_1743376_+\|coat	coat protein	NA	NA	NA	NA
WP_002208852.1\|1743642_1745049_+	hypothetical protein	Q8SBG8	Shigella_phage	2.1e-17	33.7
WP_002208850.1\|1745045_1746101_+\|tail	tail protein	M1PVV2	Vibrio_phage	1.3e-37	27.2
WP_002215460.1\|1746116_1746713_+\|plate	baseplate assembly protein	NA	NA	NA	NA
WP_002208848.1\|1746709_1747165_+	hypothetical protein	A0A0C4UR04	Shigella_phage	4.3e-17	43.8
WP_002208847.1\|1747168_1748305_+\|plate	baseplate J/gp47 family protein	B5TK75	Pseudomonas_phage	4.5e-31	30.5
WP_002215458.1\|1748301_1748562_+	DUF2313 domain-containing protein	NA	NA	NA	NA
WP_002208846.1\|1748558_1748906_+	DUF2313 domain-containing protein	A0A2P9JZK7	Alteromonadaceae_phage	6.4e-21	41.3
WP_002208845.1\|1749002_1749782_+\|tail	tail fiber protein	Q9MCR6	Enterobacteria_phage	7.1e-52	52.4

DBSCAN-SWA_6

1872642 : 2034842

120

Escherichia_phage(15.62%)

plate,protease,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002211349.1\|1872642_1872963_+\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	8.2e-15	42.7
WP_002211348.1\|1872988_1875265_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	7.4e-166	41.7
WP_002213759.1\|1875557_1876016_+\|transposase	IS200/IS605-like element IS1541A family transposase	NA	NA	NA	NA
WP_002211347.1\|1876387_1876606_-	translation initiation factor IF-1	NA	NA	NA	NA
WP_002211346.1\|1876771_1877482_-\|tRNA	leucyl/phenylalanyl-tRNA--protein transferase	NA	NA	NA	NA
WP_002211344.1\|1877700_1879425_-	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	A0A2R8FG22	Brazilian_cedratvirus	3.3e-17	31.8
WP_002217690.1\|1879427_1881194_-	cysteine/glutathione ABC transporter permease/ATP-binding protein CydD	W8CYL7	Bacillus_phage	6.8e-26	24.9
WP_002211341.1\|1881652_1882615_-	thioredoxin-disulfide reductase	A0A2I2L5E1	Orpheovirus	4.9e-63	45.7
WP_002211340.1\|1883381_1883876_+	leucine-responsive transcriptional regulator Lrp	NA	NA	NA	NA
WP_002211339.1\|1883998_1887916_+	DNA translocase FtsK	A0A218M9A2	Mycobacterium_phage	1.5e-89	48.8
WP_002211338.1\|1888108_1888717_+	outer membrane lipoprotein chaperone LolA	NA	NA	NA	NA
WP_002228009.1\|1888727_1890071_+	replication-associated recombination protein A	G3MBE0	Bacillus_virus	5.4e-76	39.4
WP_002211336.1\|1890312_1891605_+\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	4.0e-92	43.5
WP_001297096.1\|1892473_1893253_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_000255944.1\|1893252_1894275_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_002211334.1\|1895120_1895855_-	pyruvate formate lyase 1-activating protein	A0A2P0VNQ0	Tetraselmis_virus	3.6e-21	27.4
WP_002211333.1\|1896841_1897516_+	glycosyltransferase family 25 protein	A0A2H4UUT1	Bodo_saltans_virus	7.8e-31	40.5
WP_002211332.1\|1897633_1899916_-	formate C-acetyltransferase	A0A2P0VNR5	Tetraselmis_virus	1.6e-157	41.2
WP_002211331.1\|1899971_1900829_-	formate transporter FocA	NA	NA	NA	NA
WP_002211330.1\|1901525_1903292_-	30S ribosomal protein S12 methylthiotransferase accessory protein YcaO	NA	NA	NA	NA
WP_002211329.1\|1903440_1904478_+	L-asparaginase 2	NA	NA	NA	NA
WP_002211328.1\|1904746_1905841_+	hemagglutinin	B0FIT1	Escherichia_phage	3.7e-06	32.7
WP_002211327.1\|1905861_1907709_+	hypothetical protein	NA	NA	NA	NA
WP_002211326.1\|1908075_1909161_+	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	4.4e-84	46.1
WP_002211325.1\|1909323_1910610_+	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_002211324.1\|1910922_1911615_+	(d)CMP kinase	NA	NA	NA	NA
WP_002211323.1\|1911788_1913462_+	30S ribosomal protein S1	NA	NA	NA	NA
WP_002211322.1\|1913522_1913807_+	integration host factor subunit beta	A7KV42	Bacillus_phage	2.4e-10	40.2
WP_002211321.1\|1914353_1916645_+	ComEC family protein	NA	NA	NA	NA
WP_002211320.1\|1916680_1918429_+	lipid A ABC transporter ATP-binding protein/permease MsbA	W8CYL7	Bacillus_phage	8.7e-66	31.5
WP_002211319.1\|1918425_1919412_+	tetraacyldisaccharide 4'-kinase	NA	NA	NA	NA
WP_002226050.1\|1919419_1920847_-	VOC family protein	NA	NA	NA	NA
WP_002211317.1\|1921573_1921783_+	cold-shock protein	A0A1W6JNX5	Morganella_phage	3.0e-10	50.0
WP_002211315.1\|1922330_1922513_+	hypothetical protein	NA	NA	NA	NA
WP_002211314.1\|1922509_1923262_+	3-deoxy-manno-octulosonate cytidylyltransferase	NA	NA	NA	NA
WP_002211313.1\|1923624_1924518_+	YcbJ family phosphotransferase	NA	NA	NA	NA
WP_002211311.1\|1925290_1926076_+\|tRNA	tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM	NA	NA	NA	NA
WP_002211310.1\|1926072_1927395_+	chromosome partition protein MukF	NA	NA	NA	NA
WP_002211309.1\|1927375_1928104_+	chromosome partition protein MukE	NA	NA	NA	NA
WP_002211308.1\|1928100_1932558_+	chromosome partition protein MukB	NA	NA	NA	NA
WP_002213759.1\|1932773_1933232_+\|transposase	IS200/IS605-like element IS1541A family transposase	NA	NA	NA	NA
WP_002217987.1\|1933515_1935372_+	L,D-transpeptidase	NA	NA	NA	NA
WP_002211305.1\|1935595_1936144_+	YcbK family protein	A0A0K1LLY2	Rhodobacter_phage	7.8e-05	34.7
WP_002211304.1\|1936204_1936852_+	MBL fold metallo-hydrolase	A0A1X9I5D3	Streptococcus_phage	2.2e-22	32.3
WP_002430096.1\|1937005_1937122_-	hypothetical protein	NA	NA	NA	NA
WP_002211303.1\|1937275_1938466_-	aspartate/tyrosine/aromatic aminotransferase	NA	NA	NA	NA
WP_002354007.1\|1938722_1939802_-	porin OmpF	Q1MVN1	Enterobacteria_phage	3.2e-111	56.5
WP_002211301.1\|1940102_1941503_-\|tRNA	asparagine--tRNA ligase	A0A167RLM0	Powai_lake_megavirus	6.5e-80	35.2
WP_002228013.1\|1942001_1943207_-	nicotinate phosphoribosyltransferase	NA	NA	NA	NA
WP_002220013.1\|1943922_1946538_+	aminopeptidase N	NA	NA	NA	NA
WP_002211296.1\|1947155_1948166_+	quinone-dependent dihydroorotate dehydrogenase	NA	NA	NA	NA
WP_002211295.1\|1948348_1948900_+	cell division protein ZapC	NA	NA	NA	NA
WP_002363919.1\|1948925_1950035_-	MOSC domain-containing protein	NA	NA	NA	NA
WP_002211293.1\|1950137_1952258_+	bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL	NA	NA	NA	NA
WP_002211292.1\|1952263_1954177_+	ABC transporter ATP-binding protein	A0A2K9L3Z8	Tupanvirus	1.5e-47	28.9
WP_002211291.1\|1954305_1955592_+	membrane integrity-associated transporter subunit PqiA	NA	NA	NA	NA
WP_002211290.1\|1955578_1957231_+	intermembrane transport protein PqiB	NA	NA	NA	NA
WP_002211289.1\|1957227_1957806_+	membrane integrity-associated transporter subunit PqiC	NA	NA	NA	NA
WP_002228015.1\|1958075_1958243_+	ribosome modulation factor	NA	NA	NA	NA
WP_002213775.1\|1958440_1958899_+\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_001297096.1\|1960059_1960839_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_000255944.1\|1960838_1961861_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_002211286.1\|1962494_1962683_+	hypothetical protein	NA	NA	NA	NA
WP_002220006.1\|1962948_1963467_-	bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase	NA	NA	NA	NA
WP_002224683.1\|1963535_1965287_-\|protease	Lon protease family protein	NA	NA	NA	NA
WP_002226586.1\|1965497_1965953_+	macrodomain Ter protein MatP	NA	NA	NA	NA
WP_002213775.1\|1966121_1966580_-\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002213066.1\|1966769_1967831_-	porin OmpA	NA	NA	NA	NA
WP_002213065.1\|1968188_1968695_-	cell division inhibitor SulA	NA	NA	NA	NA
WP_002213064.1\|1968923_1969559_+	TfoX/Sxy family DNA transformation protein	NA	NA	NA	NA
WP_002213063.1\|1969660_1971799_-	TIGR01666 family membrane protein	NA	NA	NA	NA
WP_002213062.1\|1971828_1972275_-	YccF domain-containing protein	NA	NA	NA	NA
WP_002221095.1\|1972468_1974523_+	DNA helicase IV	A7KV33	Bacillus_phage	1.5e-16	25.8
WP_002213060.1\|1974583_1975048_-	methylglyoxal synthase	NA	NA	NA	NA
WP_002213058.1\|1975226_1975907_-	DUF2057 family protein	NA	NA	NA	NA
WP_002213056.1\|1976222_1976639_+	CoA-binding protein	NA	NA	NA	NA
WP_002213054.1\|1976747_1977065_-	heat shock protein HspQ	NA	NA	NA	NA
WP_002213052.1\|1977125_1978316_-	23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI	W6LLI2	Streptococcus_phage	2.1e-26	28.1
WP_002213049.1\|1978409_1978688_+	acylphosphatase	NA	NA	NA	NA
WP_002213046.1\|1978739_1979069_-	sulfurtransferase TusE	NA	NA	NA	NA
WP_002213039.1\|1982711_1985129_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_002213038.1\|1985282_1986029_-	SDR family oxidoreductase	F2NZ40	Diadromus_pulchellus_ascovirus	3.3e-14	31.4
WP_002213036.1\|1986759_1986978_+	hypothetical protein	NA	NA	NA	NA
WP_002213034.1\|1987241_1987766_+	beta-hydroxyacyl-ACP dehydratase	NA	NA	NA	NA
WP_002213032.1\|1987755_1989039_+	beta-ketoacyl-[acyl-carrier-protein] synthase family protein	NA	NA	NA	NA
WP_002213030.1\|1989040_1989778_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_002213028.1\|1989793_1991032_+	hydroxymethylglutaryl-CoA synthase family protein	NA	NA	NA	NA
WP_002213026.1\|1991024_1991744_+	enoyl-CoA hydratase/isomerase family protein	NA	NA	NA	NA
WP_002213025.1\|1991745_1992498_+	enoyl-CoA hydratase	NA	NA	NA	NA
WP_002213024.1\|1992500_1993289_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_162006469.1\|1993375_1993816_+	lipocalin-like domain-containing protein	NA	NA	NA	NA
WP_002213017.1\|1993853_1994102_+	acyl carrier protein	NA	NA	NA	NA
WP_002213016.1\|1994200_1995049_+	ACP S-malonyltransferase	NA	NA	NA	NA
WP_002211662.1\|1996037_1996538_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_002215896.1\|1996580_1998125_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_002211664.1\|1998136_1999489_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_002210015.1\|1999485_2000172_+	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_002228049.1\|2000171_2001908_+	OmpA family protein	NA	NA	NA	NA
WP_002210014.1\|2001911_2002403_+	Hcp family type VI secretion system effector	NA	NA	NA	NA
WP_002210013.1\|2002820_2005469_+	type VI secretion system ATPase TssH	K4FB40	Cronobacter_phage	4.8e-92	29.5
WP_152329052.1\|2005465_2007814_+	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	4.5e-17	32.1
WP_002211929.1\|2007829_2010130_+	M23 family metallopeptidase	NA	NA	NA	NA
WP_002211930.1\|2010126_2010900_+	hypothetical protein	NA	NA	NA	NA
WP_002211931.1\|2011053_2011314_+	DUF2345 domain-containing protein	NA	NA	NA	NA
WP_002211932.1\|2011329_2013513_+	M23 family metallopeptidase	NA	NA	NA	NA
WP_002214564.1\|2013685_2014156_+	hypothetical protein	NA	NA	NA	NA
WP_002211935.1\|2016320_2017553_+	hypothetical protein	NA	NA	NA	NA
WP_002211936.1\|2017549_2020972_+	type VI secretion system membrane subunit	NA	NA	NA	NA
WP_002211937.1\|2021015_2022617_+	type VI secretion system protein TssA	NA	NA	NA	NA
WP_002211938.1\|2022634_2023693_+	PAAR domain protein	NA	NA	NA	NA
WP_002211939.1\|2023707_2024163_+	hypothetical protein	NA	NA	NA	NA
WP_002211940.1\|2024383_2026147_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_002211941.1\|2026110_2027196_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_002214552.1\|2027170_2027752_+	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_002211943.1\|2027751_2028204_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_002211944.1\|2028228_2029596_+	membrane protein	NA	NA	NA	NA
WP_002211945.1\|2029807_2030431_-	hypothetical protein	NA	NA	NA	NA
WP_002227996.1\|2031113_2032709_+	ABC-F family ATPase	A0A2K9L0W2	Tupanvirus	6.1e-58	28.5
WP_002211947.1\|2032936_2033590_+	hypothetical protein	NA	NA	NA	NA
WP_002209743.1\|2033633_2034842_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8

DBSCAN-SWA_7

2521142 : 2621628

104

Escherichia_phage(14.81%)

transposase,lysis,integrase,tRNA,tail

attL 2531694:2531724|attR 2572708:2572738

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002211184.1\|2521142_2521841_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA
WP_002211183.1\|2521977_2522583_+	Slp family lipoprotein	NA	NA	NA	NA
WP_087768167.1\|2522583_2522691_-	gluconate 5-dehydrogenase	NA	NA	NA	NA
WP_002220632.1\|2523225_2524914_+	long-chain-fatty-acid--CoA ligase FadD	A0A2H4PQM9	Staphylococcus_phage	3.0e-31	28.9
WP_002211181.1\|2525073_2526195_+	ribonuclease D	NA	NA	NA	NA
WP_002211180.1\|2526431_2526701_-	cell division topological specificity factor MinE	NA	NA	NA	NA
WP_002211179.1\|2526704_2527517_-	septum site-determining protein MinD	NA	NA	NA	NA
WP_002220631.1\|2527541_2528228_-	septum site-determining protein MinC	NA	NA	NA	NA
WP_002211743.1\|2528948_2529221_+	hypothetical protein	NA	NA	NA	NA
WP_002215627.1\|2529361_2530447_+	lytic murein transglycosylase	NA	NA	NA	NA
WP_002211740.1\|2530517_2531174_+	fumarylacetoacetate hydrolase family protein	NA	NA	NA	NA
WP_002211739.1\|2531276_2531723_+	YcgN family cysteine cluster protein	NA	NA	NA	NA
2531694:2531724	attL	NA	NA	NA	NA
WP_002211738.1\|2531749_2532988_-\|integrase	site-specific integrase	Q20GI2	Phage_258-320	2.3e-121	53.3
WP_000255944.1\|2533057_2534080_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_001297096.1\|2534079_2534859_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_002215632.1\|2535026_2535287_-	excisionase family protein	Q859D3	Escherichia_coli_phage	1.7e-10	42.9
WP_071525537.1\|2535586_2536336_-	DNA adenine methylase	Q5QF26	Pseudomonas_virus	1.5e-54	48.5
WP_002211736.1\|2536311_2536758_+	recombination protein NinB	A0A2H4J8D9	uncultured_Caudovirales_phage	3.9e-47	62.5
WP_002211735.1\|2536831_2537437_+	recombination protein NinG	A0A1P8DTE0	Proteus_phage	2.8e-56	56.9
WP_002215636.1\|2537437_2537827_+	antitermination protein	A0A1W6JNX1	Morganella_phage	1.4e-45	68.8
WP_002215638.1\|2537830_2538049_+	hypothetical protein	NA	NA	NA	NA
WP_002211732.1\|2538097_2538661_+	hypothetical protein	B6SD63	Bacteriophage	9.4e-30	58.0
WP_002211731.1\|2539084_2539294_+	hypothetical protein	NA	NA	NA	NA
WP_002215644.1\|2539290_2539566_-	hypothetical protein	NA	NA	NA	NA
WP_002430108.1\|2539811_2540009_+	hypothetical protein	B6SD15	Bacteriophage	4.9e-18	64.4
WP_002211730.1\|2540039_2540552_+	lysozyme	I6PBN2	Cronobacter_phage	9.7e-50	61.6
WP_002211729.1\|2540536_2540995_+\|lysis	lysis protein	A0A2H4JHL8	uncultured_Caudovirales_phage	4.9e-21	45.3
WP_002211727.1\|2541540_2542254_+	hypothetical protein	Q5MBW0	Stx1-converting_phage	7.6e-69	60.2
WP_002211725.1\|2542710_2543346_+	hypothetical protein	I6S676	Salmonella_phage	7.2e-87	71.4
WP_002211724.1\|2543376_2543826_+	DUF2280 domain-containing protein	I6S1P9	Salmonella_phage	1.0e-47	72.9
WP_002211723.1\|2543829_2544414_+	hypothetical protein	A0A0R6PHH0	Moraxella_phage	4.8e-69	70.7
WP_002209743.1\|2544461_2545670_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_002211722.1\|2545674_2546649_+	hypothetical protein	A0A1W6JNY3	Morganella_phage	2.3e-153	81.1
WP_002228445.1\|2546648_2547377_+	hypothetical protein	A0A1B0VMH0	Pseudomonas_phage	4.6e-61	51.4
WP_002228446.1\|2547395_2548037_+	DUF4055 domain-containing protein	A0A1B0VMH0	Pseudomonas_phage	3.8e-59	54.1
WP_002211721.1\|2548037_2549150_+	hypothetical protein	I6PD76	Cronobacter_phage	6.0e-121	58.2
WP_002211720.1\|2549271_2550045_+	hypothetical protein	A0A1B0VMG1	Pseudomonas_phage	2.8e-69	62.3
WP_002211719.1\|2550058_2551264_+	hypothetical protein	A0A1B0VMF8	Pseudomonas_phage	1.8e-142	79.2
WP_002211718.1\|2551311_2551794_+	hypothetical protein	G8C7P9	Escherichia_phage	6.4e-27	46.1
WP_002211717.1\|2551790_2552045_+	hypothetical protein	J9Q7U0	Salmonella_phage	2.2e-18	53.1
WP_002211716.1\|2552046_2552397_+	hypothetical protein	I6PD77	Cronobacter_phage	6.9e-31	56.0
WP_002211715.1\|2552398_2552983_+	hypothetical protein	G8C7Q1	Escherichia_phage	3.6e-48	52.1
WP_002211714.1\|2552979_2553387_+	DUF4128 domain-containing protein	NA	NA	NA	NA
WP_002211713.1\|2553452_2554373_+\|tail	phage tail protein	I6PBN6	Cronobacter_phage	4.4e-61	49.1
WP_002211712.1\|2554385_2554697_+	hypothetical protein	I6PDG2	Cronobacter_phage	1.4e-30	58.3
WP_071525538.1\|2554744_2555005_+	hypothetical protein	A0A0S2SY90	Pseudomonas_phage	3.7e-13	50.0
WP_002211711.1\|2555005_2558509_+\|tail	phage tail tape measure protein	K7PMB9	Enterobacterial_phage	5.2e-118	33.2
WP_002211710.1\|2558511_2558853_+\|tail	phage tail protein	Q6UAW6	Klebsiella_phage	1.7e-21	50.0
WP_002211709.1\|2559026_2559779_+\|tail	phage minor tail protein L	A0A1W6JNX9	Morganella_phage	9.4e-102	67.7
WP_002211708.1\|2559781_2560492_+	peptidase P60	K7P6F5	Enterobacteria_phage	1.3e-108	76.8
WP_002211707.1\|2560752_2561385_+	hypothetical protein	NA	NA	NA	NA
WP_002211706.1\|2561463_2561895_-	Arc family DNA-binding protein	G9L6D6	Escherichia_phage	2.5e-30	58.4
WP_002211705.1\|2562018_2562186_+	hypothetical protein	G9L6D7	Escherichia_phage	5.2e-13	61.8
WP_002211704.1\|2562259_2563267_+	hypothetical protein	A0A2H4J0P1	uncultured_Caudovirales_phage	4.1e-36	33.0
WP_002214482.1\|2563365_2563917_+	zinc ribbon domain-containing protein	S4TR42	Salmonella_phage	9.5e-27	58.0
WP_002211701.1\|2564059_2564275_+	hypothetical protein	NA	NA	NA	NA
WP_002211700.1\|2564330_2564951_+\|tail	tail assembly protein	K7PGY0	Enterobacteria_phage	3.2e-55	57.0
WP_002359202.1\|2565125_2565347_-	hypothetical protein	NA	NA	NA	NA
WP_002211698.1\|2565522_2568726_+	host specificity protein J	F1C571	Cronobacter_phage	0.0e+00	60.5
WP_002211697.1\|2568725_2569724_+	hypothetical protein	NA	NA	NA	NA
WP_002211696.1\|2569740_2570658_+	hypothetical protein	NA	NA	NA	NA
WP_097608205.1\|2570719_2571088_+\|tail	phage tail protein	B6SCW7	Bacteriophage	5.0e-08	42.0
WP_002209743.1\|2571308_2572517_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_002214492.1\|2572821_2573994_-	MFS transporter	NA	NA	NA	NA
2572708:2572738	attR	NA	NA	NA	NA
WP_002211693.1\|2573997_2575197_-	cysteine desulfurase	A0A1X7QGF3	Faustovirus	2.4e-38	29.6
WP_002211692.1\|2575213_2575954_-	hypothetical protein	NA	NA	NA	NA
WP_002214494.1\|2577045_2577402_+	hypothetical protein	NA	NA	NA	NA
WP_002227934.1\|2577818_2578349_-	disulfide bond formation protein DsbB	NA	NA	NA	NA
WP_002211689.1\|2578584_2580159_-	sodium/proton antiporter NhaB	NA	NA	NA	NA
WP_002211688.1\|2580402_2581122_+	fatty acid metabolism transcriptional regulator FadR	NA	NA	NA	NA
WP_002211687.1\|2581339_2582875_-	SpoVR family protein	NA	NA	NA	NA
WP_002211686.1\|2583340_2584645_+	D-amino acid dehydrogenase	NA	NA	NA	NA
WP_002216508.1\|2584660_2585863_-	multidrug effflux MFS transporter	S4TR35	Salmonella_phage	7.6e-29	29.1
WP_002211685.1\|2586127_2586997_-	pirin family protein	NA	NA	NA	NA
WP_002211684.1\|2587194_2588100_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002211683.1\|2588134_2589253_-	DMT family transporter	NA	NA	NA	NA
WP_002216501.1\|2589360_2590635_-	YeaH/YhbH family protein	A0A140HLI1	Bacillus_phage	1.5e-11	37.1
WP_002211681.1\|2590784_2592719_-	protein kinase YeaG	NA	NA	NA	NA
WP_002430110.1\|2593162_2593912_+	MipA/OmpV family protein	NA	NA	NA	NA
WP_002211679.1\|2593984_2594860_-	D-hexose-6-phosphate mutarotase	NA	NA	NA	NA
WP_002224141.1\|2595173_2596169_-	glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_002211677.1\|2596516_2596930_+	peptide-methionine (R)-S-oxide reductase MsrB	NA	NA	NA	NA
WP_002217933.1\|2597000_2597273_+	YeaC family protein	NA	NA	NA	NA
WP_002211676.1\|2597406_2598054_-	bifunctional nicotinamidase/pyrazinamidase	A0A2K9L6K4	Tupanvirus	1.8e-21	33.0
WP_002211675.1\|2598068_2599085_-	asparaginase	NA	NA	NA	NA
WP_002211674.1\|2599201_2601052_-	signal peptide peptidase SppA	NA	NA	NA	NA
WP_002211673.1\|2601214_2601766_+	NAD(P)H nitroreductase	NA	NA	NA	NA
WP_002211671.1\|2601990_2603037_+	selenide, water dikinase SelD	NA	NA	NA	NA
WP_002211670.1\|2603098_2605024_+	DNA topoisomerase III	A0A1X9I6W8	Streptococcus_phage	4.2e-37	30.4
WP_002211669.1\|2605020_2605311_+	DUF1496 domain-containing protein	NA	NA	NA	NA
WP_002211668.1\|2605323_2605710_-	pyrimidine (deoxy)nucleoside triphosphate diphosphatase	NA	NA	NA	NA
WP_002211669.1\|2606549_2606840_+	DUF1496 domain-containing protein	NA	NA	NA	NA
WP_002211668.1\|2606852_2607239_-	pyrimidine (deoxy)nucleoside triphosphate diphosphatase	NA	NA	NA	NA
WP_002211667.1\|2607336_2608143_-	exodeoxyribonuclease III	NA	NA	NA	NA
WP_002211665.1\|2608952_2609813_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002209743.1\|2610684_2611893_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_002210667.1\|2611855_2612725_-	formyltetrahydrofolate deformylase	M4QRX9	Synechococcus_phage	5.5e-13	37.3
WP_002210666.1\|2612808_2613273_-	YchJ family protein	NA	NA	NA	NA
WP_002210665.1\|2614606_2615623_+	two-component system response regulator RssB	NA	NA	NA	NA
WP_016582239.1\|2615929_2617276_+	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	4.3e-81	38.0
WP_002223593.1\|2617710_2618118_-	DNA-binding transcriptional regulator H-NS	NA	NA	NA	NA
WP_002210659.1\|2618867_2619458_+	thymidine kinase	A0A1Z1LYD5	Serratia_phage	1.5e-54	55.8
WP_001297096.1\|2619826_2620606_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_000255944.1\|2620605_2621628_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0

DBSCAN-SWA_8

2885123 : 2943890

Tupanvirus(18.18%)

tRNA,transposase,protease,coat

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002211831.1\|2885123_2887511_-\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_002211832.1\|2887524_2888508_-\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2K9L3A8	Tupanvirus	7.6e-35	38.5
WP_152328947.1\|2888864_2888912_-	pheST operon leader peptide PheM	NA	NA	NA	NA
WP_002211833.1\|2889006_2889363_-	50S ribosomal protein L20	NA	NA	NA	NA
WP_002211834.1\|2889400_2889598_-	50S ribosomal protein L35	NA	NA	NA	NA
WP_002227898.1\|2889694_2890246_-	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	2.6e-16	33.7
WP_002211836.1\|2890249_2892178_-\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	1.1e-127	37.1
WP_002216696.1\|2892568_2892781_+	KTSC domain-containing protein	A0A0K1LMB5	Caulobacter_phage	9.9e-09	42.0
WP_002211839.1\|2893539_2893791_-	hypothetical protein	NA	NA	NA	NA
WP_002211840.1\|2894109_2894793_+	MarC family NAAT transporter	NA	NA	NA	NA
WP_002216686.1\|2894914_2895577_-	transglycosylase SLT domain-containing protein	NA	NA	NA	NA
WP_002211842.1\|2895788_2896757_+	iron/manganese ABC transporter substrate-binding protein YfeA	NA	NA	NA	NA
WP_002211843.1\|2896753_2897644_+	iron/manganese ABC transporter ATP-binding protein YfeB	A0A1V0SKJ1	Klosneuvirus	2.9e-09	27.5
WP_002211844.1\|2897643_2898528_+	iron/manganese ABC transporter permease subunit YfeC	NA	NA	NA	NA
WP_002211845.1\|2898524_2899418_+	iron/manganese ABC transporter permease subunit YfeD	NA	NA	NA	NA
WP_002216683.1\|2899485_2899698_+	hypothetical protein	NA	NA	NA	NA
WP_002211846.1\|2899722_2900598_+	fructosamine kinase family protein	NA	NA	NA	NA
WP_002211847.1\|2900726_2901281_-	yfeABCD regulator yfeE	NA	NA	NA	NA
WP_002220277.1\|2901691_2902357_+	hexitol phosphatase HxpB	NA	NA	NA	NA
WP_002209743.1\|2902607_2903816_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_002210828.1\|2903863_2904214_-	cupin domain-containing protein	NA	NA	NA	NA
WP_002210829.1\|2904549_2905386_+	5-dehydro-4-deoxy-D-glucuronate isomerase	NA	NA	NA	NA
WP_002210830.1\|2905477_2906239_+	2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD	Q06VL0	Trichoplusia_ni_ascovirus	3.1e-20	32.9
WP_002210831.1\|2906574_2908242_+	pectate disaccharide-lyase	NA	NA	NA	NA
WP_002210832.1\|2908282_2909173_+	sugar ABC transporter permease	NA	NA	NA	NA
WP_002210833.1\|2909165_2910086_+	carbohydrate ABC transporter permease	NA	NA	NA	NA
WP_002210834.1\|2910099_2911227_+	ABC transporter ATP-binding protein	W5SAS9	Pithovirus	1.6e-12	26.5
WP_002210835.1\|2911242_2912535_+	carbohydrate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002210836.1\|2912832_2913543_+	porin	NA	NA	NA	NA
WP_002210837.1\|2914022_2914571_+	metal-dependent hydrolase	A0A127AVX7	Bacillus_phage	4.0e-09	32.9
WP_002210838.1\|2914774_2916166_+	L-cystine transporter	NA	NA	NA	NA
WP_002210839.1\|2916380_2917232_-	N-acetylmuramoyl-L-alanine amidase	A0A1W6DX33	Sphingobium_phage	1.3e-11	28.8
WP_002210840.1\|2917616_2918408_-	DNA-binding transcriptional regulator KdgR	NA	NA	NA	NA
WP_002210841.1\|2918594_2919761_-	oligogalacturonate lyase	NA	NA	NA	NA
WP_002210842.1\|2920087_2921455_+	MFS transporter	NA	NA	NA	NA
WP_002210843.1\|2921508_2922312_-	molecular chaperone	NA	NA	NA	NA
WP_002215120.1\|2922308_2923472_-	type 1 fimbrial protein	NA	NA	NA	NA
WP_002210844.1\|2923468_2926081_-	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_002215118.1\|2926162_2926942_-	fimbrial chaperone	NA	NA	NA	NA
WP_002210846.1\|2927094_2927637_-	type 1 fimbrial protein	NA	NA	NA	NA
WP_002210847.1\|2928294_2929176_-\|protease	protease HtpX	NA	NA	NA	NA
WP_002210848.1\|2929649_2931722_-	carboxy terminal-processing peptidase	A0A0R6PIZ1	Moraxella_phage	4.0e-86	34.8
WP_002210849.1\|2931741_2932455_-	RNA chaperone ProQ	NA	NA	NA	NA
WP_002210850.1\|2932550_2933048_-	GAF domain-containing protein	NA	NA	NA	NA
WP_002367629.1\|2933279_2934527_+	membrane integrity lipid transport subunit YebS	NA	NA	NA	NA
WP_002216616.1\|2934495_2937147_+	PqiB family protein	NA	NA	NA	NA
WP_002210852.1\|2937625_2938180_+\|coat	spore coat U domain-containing protein	NA	NA	NA	NA
WP_002216613.1\|2938185_2938716_+\|coat	spore coat U domain-containing protein	NA	NA	NA	NA
WP_002216611.1\|2938736_2939294_+\|coat	spore coat U domain-containing protein	NA	NA	NA	NA
WP_002210856.1\|2939324_2940077_+	molecular chaperone	NA	NA	NA	NA
WP_002210857.1\|2940247_2942695_+	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_002210858.1\|2942900_2943890_+\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA

DBSCAN-SWA_9

3222365 : 3292391

uncultured_virus(22.22%)

plate,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_032465663.1\|3222365_3223196_-\|tRNA	tRNA pseudouridine(38-40) synthase TruA	NA	NA	NA	NA
WP_002209726.1\|3223246_3224257_-	aspartate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_002209725.1\|3224426_3225554_-	4-phosphoerythronate dehydrogenase PdxB	A0A285PXZ1	Cedratvirus	6.1e-20	27.9
WP_002209724.1\|3225600_3226386_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_002209722.1\|3226611_3227529_+	DMT family transporter	NA	NA	NA	NA
WP_002209721.1\|3227813_3228851_+	flagella biosynthesis regulator Flk	NA	NA	NA	NA
WP_002209720.1\|3229192_3229723_-	type 1 fimbrial protein	NA	NA	NA	NA
WP_002216161.1\|3230510_3231206_+	aspartate/glutamate racemase family protein	NA	NA	NA	NA
WP_002209717.1\|3231613_3232837_-	beta-ketoacyl-ACP synthase I	NA	NA	NA	NA
WP_002209716.1\|3233008_3235078_+\|tRNA	bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC	NA	NA	NA	NA
WP_002209715.1\|3235255_3235534_-	YfcL family protein	NA	NA	NA	NA
WP_002209714.1\|3235591_3236134_-	elongation factor P hydroxylase	NA	NA	NA	NA
WP_002209713.1\|3236233_3237040_-	TSUP family transporter	NA	NA	NA	NA
WP_002225365.1\|3237043_3237871_-	penicillin-insensitive murein endopeptidase	NA	NA	NA	NA
WP_002209711.1\|3237876_3238962_-	chorismate synthase	A0A291AU41	Pandoravirus	2.7e-89	47.4
WP_002209710.1\|3239038_3239971_-	50S ribosomal protein L3 N(5)-glutamine methyltransferase	NA	NA	NA	NA
WP_002227846.1\|3240340_3240871_+	endonuclease SmrB	NA	NA	NA	NA
WP_002209707.1\|3241248_3241740_-	phosphohistidine phosphatase SixA	NA	NA	NA	NA
WP_002209705.1\|3242308_3244633_-	fatty acid oxidation complex subunit alpha FadJ	NA	NA	NA	NA
WP_002209704.1\|3244632_3245943_-	acetyl-CoA C-acyltransferase FadI	NA	NA	NA	NA
WP_002227845.1\|3246229_3246526_-	YfcZ/YiiS family protein	NA	NA	NA	NA
WP_002209702.1\|3246939_3248205_+	long-chain fatty acid transporter FadL	NA	NA	NA	NA
WP_002209701.1\|3248311_3249076_-	phospholipid-binding lipoprotein MlaA	NA	NA	NA	NA
WP_002209700.1\|3249111_3250338_-	c-type cytochrome biogenesis protein CcmI	NA	NA	NA	NA
WP_002214855.1\|3250337_3250850_-	cytochrome c-type biogenesis protein CcmH	NA	NA	NA	NA
WP_002209699.1\|3250846_3251413_-	DsbE family thiol:disulfide interchange protein	NA	NA	NA	NA
WP_002209698.1\|3251409_3253380_-	heme lyase CcmF/NrfE family subunit	NA	NA	NA	NA
WP_002209697.1\|3253376_3253871_-	cytochrome c maturation protein CcmE	NA	NA	NA	NA
WP_002209696.1\|3253867_3254170_-	heme exporter protein CcmD	NA	NA	NA	NA
WP_002209695.1\|3254166_3254904_-	heme ABC transporter permease	NA	NA	NA	NA
WP_002209694.1\|3254966_3255626_-	heme exporter protein CcmB	NA	NA	NA	NA
WP_002209693.1\|3255595_3256252_-	cytochrome c biogenesis heme-transporting ATPase CcmA	A0A1V0SE00	Indivirus	4.8e-09	24.7
WP_002209692.1\|3256696_3257164_-	hypothetical protein	NA	NA	NA	NA
WP_002209691.1\|3257779_3258322_+	LemA family protein	NA	NA	NA	NA
WP_002209690.1\|3258326_3260366_+	DUF2207 domain-containing protein	NA	NA	NA	NA
WP_002209688.1\|3260741_3261083_+	alkylphosphonate utilization protein	NA	NA	NA	NA
WP_152329057.1\|3261157_3261499_-	hypothetical protein	NA	NA	NA	NA
WP_002209743.1\|3261555_3262764_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_002209686.1\|3262852_3263332_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_002209685.1\|3263460_3264267_-	ImpE family protein	NA	NA	NA	NA
WP_002354537.1\|3264286_3265129_-	TagK domain-containing protein	NA	NA	NA	NA
WP_002209684.1\|3265134_3265395_-	hypothetical protein	NA	NA	NA	NA
WP_011055427.1\|3265493_3268079_-	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	3.3e-29	23.1
WP_002214843.1\|3268372_3272200_-	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_002209681.1\|3272208_3273045_-	type VI secretion system protein TssL	NA	NA	NA	NA
WP_001297096.1\|3273060_3273840_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_000255944.1\|3273839_3274862_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_002211571.1\|3275540_3276890_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_002211572.1\|3276893_3277433_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_002211573.1\|3277706_3278192_-	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_002211574.1\|3278517_3280020_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_002211575.1\|3280043_3280568_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_002211576.1\|3280672_3281281_-	type 1 fimbrial protein	NA	NA	NA	NA
WP_002211577.1\|3281265_3282456_-	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_002209743.1\|3282480_3283689_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_002215157.1\|3283710_3285261_-	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_002211579.1\|3285388_3286150_-	fimbria/pilus periplasmic chaperone	NA	NA	NA	NA
WP_002211580.1\|3286306_3286852_-	type 1 fimbrial protein	NA	NA	NA	NA
WP_002215317.1\|3287052_3289728_-	type VI secretion system ATPase TssH	A0A223W0B1	Agrobacterium_phage	1.0e-81	32.3
WP_002211582.1\|3290510_3292391_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA

DBSCAN-SWA_10

3427737 : 3504175

Bacillus_phage(18.75%)

tRNA,transposase,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002213775.1\|3427737_3428196_-\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002209776.1\|3428371_3428998_-	uracil phosphoribosyltransferase	NA	NA	NA	NA
WP_002209777.1\|3429394_3430438_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D7SE90	Cyanophage	9.1e-71	41.3
WP_002209778.1\|3430552_3431191_+	phosphoribosylglycinamide formyltransferase	E3SNR5	Prochlorococcus_phage	3.1e-29	41.4
WP_002209779.1\|3431419_3431965_+	spermidine N1-acetyltransferase	NA	NA	NA	NA
WP_002209780.1\|3433475_3434288_-	phosphate ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.3e-16	32.8
WP_002214668.1\|3434315_3436028_-	phosphate ABC transporter permease PstA	NA	NA	NA	NA
WP_002214670.1\|3436027_3438259_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_002209782.1\|3438529_3440593_+	polyphosphate kinase 1	NA	NA	NA	NA
WP_002209783.1\|3440603_3442163_+	exopolyphosphatase	NA	NA	NA	NA
WP_012303868.1\|3442298_3442487_+	YfgG family protein	NA	NA	NA	NA
WP_002209784.1\|3442538_3444014_+	magnesium transporter	NA	NA	NA	NA
WP_002209785.1\|3444153_3445506_+	molecular chaperone	NA	NA	NA	NA
WP_002209786.1\|3445777_3446626_-	ABC transporter permease	NA	NA	NA	NA
WP_002209787.1\|3446687_3447953_-	ABC transporter permease	NA	NA	NA	NA
WP_002209788.1\|3447999_3449028_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002209789.1\|3449080_3450370_-	4-aminobutyrate--2-oxoglutarate transaminase	A0A1V0SKB7	Klosneuvirus	2.1e-24	27.8
WP_002209790.1\|3450551_3452057_+	PLP-dependent aminotransferase family protein	A0A1X9I5H2	Streptococcus_phage	4.0e-19	31.7
WP_002209791.1\|3452439_3453525_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	8.4e-27	34.8
WP_002214676.1\|3453888_3455223_+	MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_002209793.1\|3455222_3458381_+	MdtB/MuxB family multidrug efflux RND transporter permease subunit	NA	NA	NA	NA
WP_002209794.1\|3458377_3461452_+	multidrug efflux RND transporter permease subunit MdtC	NA	NA	NA	NA
WP_002209795.1\|3461485_3462883_+	MFS transporter	NA	NA	NA	NA
WP_002209796.1\|3464307_3465027_+	two-component system response regulator BaeR	W8CYM9	Bacillus_phage	2.3e-33	33.8
WP_002209797.1\|3465163_3465502_+	YegP family protein	NA	NA	NA	NA
WP_002209798.1\|3465776_3467171_+\|tRNA	tRNA 5-hydroxyuridine modification protein YegQ	Q6DW11	Phage_TP	1.5e-177	81.4
WP_002209799.1\|3467806_3468697_+	lipid kinase YegS	NA	NA	NA	NA
WP_002265214.1\|3468718_3468955_-	hypothetical protein	NA	NA	NA	NA
WP_002209800.1\|3468983_3469493_-	hypothetical protein	NA	NA	NA	NA
WP_002209801.1\|3470673_3471474_-	bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase	NA	NA	NA	NA
WP_002209803.1\|3471995_3472463_+	DUF943 family protein	NA	NA	NA	NA
WP_002209804.1\|3472521_3472800_+	hypothetical protein	NA	NA	NA	NA
WP_002209743.1\|3472811_3474020_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_002223532.1\|3474194_3474509_-	hypothetical protein	NA	NA	NA	NA
WP_002228617.1\|3474592_3474829_-	hypothetical protein	NA	NA	NA	NA
WP_016256670.1\|3474969_3475296_-	hypothetical protein	NA	NA	NA	NA
WP_002228620.1\|3475329_3475524_-	hypothetical protein	NA	NA	NA	NA
WP_002220152.1\|3476737_3478093_-	ATP-dependent RNA helicase RhlE	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	4.1e-55	35.6
WP_002220154.1\|3478483_3479194_+	transcriptional regulator CecR	NA	NA	NA	NA
WP_002220156.1\|3479245_3480232_+	secretion protein HlyD	NA	NA	NA	NA
WP_015683568.1\|3480245_3481988_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	6.3e-24	34.6
WP_002220159.1\|3481992_3483168_+	ABC transporter permease	NA	NA	NA	NA
WP_002220162.1\|3483180_3484287_+	ABC transporter permease	NA	NA	NA	NA
WP_002220163.1\|3484325_3484652_-	EthD family reductase	NA	NA	NA	NA
WP_002220165.1\|3484662_3484890_-	N5,N10-methylene tetrahydromethanopterin reductase	NA	NA	NA	NA
WP_002220168.1\|3485444_3486356_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_015683567.1\|3486356_3487466_-	alkene reductase	NA	NA	NA	NA
WP_002220170.1\|3487813_3489178_-	sigma 54-interacting transcriptional regulator	Q6XM27	Feldmannia_irregularis_virus	1.3e-05	29.1
WP_002220171.1\|3489164_3490979_-	PAS domain-containing sensor histidine kinase	W8CYF6	Bacillus_phage	1.0e-16	28.4
WP_002220173.1\|3491336_3491810_+	zinc resistance sensor/chaperone ZraP	NA	NA	NA	NA
WP_002213759.1\|3492615_3493074_-\|transposase	IS200/IS605-like element IS1541A family transposase	NA	NA	NA	NA
WP_002214195.1\|3494002_3494866_-	xanthosine phosphorylase	Q5YBA4	Grouper_iridovirus	2.3e-51	40.7
WP_002214197.1\|3495211_3496060_+	DMT family transporter	NA	NA	NA	NA
WP_002214199.1\|3496097_3496991_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002228035.1\|3497222_3499271_-\|holin	choline transporter	A0A2I7QNT1	Vibrio_phage	1.4e-19	28.5
WP_002218278.1\|3499635_3500232_+	transcriptional regulator BetI	NA	NA	NA	NA
WP_002218281.1\|3500289_3501762_+	betaine-aldehyde dehydrogenase	NA	NA	NA	NA
WP_002220180.1\|3501784_3503488_+\|holin	choline dehydrogenase	A0A1V0S9M4	Catovirus	9.4e-57	31.5
WP_002213775.1\|3503716_3504175_-\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA

DBSCAN-SWA_11

3573889 : 3580061

Escherichia_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002210709.1\|3573889_3574090_+	AlpA family transcriptional regulator	A0A1V0E8E5	Vibrio_phage	1.6e-08	51.7
WP_002215949.1\|3574089_3574632_+	ash family protein	NA	NA	NA	NA
WP_002215950.1\|3574624_3575584_+	toprim domain-containing protein	A0A1W6JPG0	Morganella_phage	1.6e-50	41.0
WP_002210707.1\|3575580_3576669_+	AAA family ATPase	A0A2H4JFA4	uncultured_Caudovirales_phage	1.4e-114	60.4
WP_002210705.1\|3577017_3577332_-	putative addiction module antidote protein	NA	NA	NA	NA
WP_002215951.1\|3577337_3577655_-	type II toxin-antitoxin system RelE/ParE family toxin	A0A141GEX6	Brucella_phage	2.0e-13	48.1
WP_000255944.1\|3578259_3579282_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_001297096.1\|3579281_3580061_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6

DBSCAN-SWA_12

3820059 : 3895410

Staphylococcus_phage(25.0%)

plate,protease,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002213759.1\|3820059_3820518_-\|transposase	IS200/IS605-like element IS1541A family transposase	NA	NA	NA	NA
WP_002209965.1\|3820825_3822820_-	transketolase	NA	NA	NA	NA
WP_002209967.1\|3823310_3824063_+	M48 family metallopeptidase	NA	NA	NA	NA
WP_071525520.1\|3824208_3824319_+	gluconate 5-dehydrogenase	NA	NA	NA	NA
WP_002209968.1\|3824352_3824673_-	non-heme iron oxygenase ferredoxin subunit	NA	NA	NA	NA
WP_002209969.1\|3824832_3826812_-	biosynthetic arginine decarboxylase	NA	NA	NA	NA
WP_002209971.1\|3828018_3829173_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.7e-126	62.1
WP_002228653.1\|3829365_3829878_+\|protease	SprT family zinc-dependent metalloprotease	NA	NA	NA	NA
WP_002209973.1\|3829975_3830683_+	deoxyribonuclease I	NA	NA	NA	NA
WP_002209975.1\|3830943_3831675_+	16S rRNA (uracil(1498)-N(3))-methyltransferase	NA	NA	NA	NA
WP_002209976.1\|3831700_3832660_+	glutathione synthase	NA	NA	NA	NA
WP_002209977.1\|3832775_3833339_+	YqgE/AlgH family protein	NA	NA	NA	NA
WP_002209978.1\|3833338_3833761_+	Holliday junction resolvase RuvX	NA	NA	NA	NA
WP_002209979.1\|3833940_3834825_+	N-carbamoylputrescine amidase	A7IVZ1	Paramecium_bursaria_Chlorella_virus	3.1e-80	51.0
WP_002209980.1\|3834828_3835944_+	agmatine deiminase	M1I1E2	Acanthocystis_turfacea_Chlorella_virus	3.0e-96	50.7
WP_002209981.1\|3836052_3837177_-	type IV pilus twitching motility protein PilT	NA	NA	NA	NA
WP_002215609.1\|3837196_3837895_+	YggS family pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_002209983.1\|3838027_3838849_+	pyrroline-5-carboxylate reductase	NA	NA	NA	NA
WP_002209984.1\|3839136_3839691_+	YggT family protein	NA	NA	NA	NA
WP_002215612.1\|3839687_3839978_+	YggU family protein	NA	NA	NA	NA
WP_002215614.1\|3840077_3840671_+	XTP/dITP diphosphatase	NA	NA	NA	NA
WP_002209987.1\|3840663_3841794_+	radical SAM family heme chaperone HemW	NA	NA	NA	NA
WP_042593583.1\|3841983_3851316_-	pore forming RTX toxin family protein	NA	NA	NA	NA
WP_002209989.1\|3852661_3853588_-	glutaminase B	NA	NA	NA	NA
WP_002213775.1\|3853749_3854208_-\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002209990.1\|3854409_3854736_-	YggL family protein	NA	NA	NA	NA
WP_002209991.1\|3854735_3855455_-\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_002228057.1\|3855792_3856908_+	A/G-specific adenine glycosylase	NA	NA	NA	NA
WP_002209994.1\|3857085_3857358_+	oxidative damage protection protein	NA	NA	NA	NA
WP_002209995.1\|3857540_3858617_+	membrane-bound lytic murein transglycosylase MltC	NA	NA	NA	NA
WP_002209997.1\|3858916_3860017_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002209998.1\|3860120_3862154_+	TonB-dependent siderophore receptor	A0A0P0I887	Acinetobacter_phage	4.5e-05	26.1
WP_002209999.1\|3862236_3863220_-	ABC transporter permease	NA	NA	NA	NA
WP_002210000.1\|3863252_3864752_-	sugar ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	5.2e-19	31.7
WP_002210001.1\|3864797_3865757_-	substrate-binding domain-containing protein	NA	NA	NA	NA
WP_002210002.1\|3866312_3868475_-	ornithine decarboxylase SpeF	NA	NA	NA	NA
WP_002210005.1\|3869803_3870439_-	DUF2345 domain-containing protein	NA	NA	NA	NA
WP_086016632.1\|3871046_3871744_-\|transposase	IS1 family transposase	A0A0U2RK18	Escherichia_phage	1.3e-60	48.5
WP_002210008.1\|3871839_3872607_-	hypothetical protein	NA	NA	NA	NA
WP_002210009.1\|3872593_3874891_-	M23 family metallopeptidase	NA	NA	NA	NA
WP_002210010.1\|3874906_3875542_-	DUF2345 domain-containing protein	NA	NA	NA	NA
WP_002216110.1\|3876766_3876961_-	hypothetical protein	NA	NA	NA	NA
WP_016257642.1\|3877154_3877511_-	hypothetical protein	NA	NA	NA	NA
WP_002210011.1\|3877654_3879877_-	hydroxyethylthiazole kinase	NA	NA	NA	NA
WP_152329053.1\|3879891_3882240_-	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	3.1e-18	33.3
WP_002211927.1\|3882242_3884885_-	type VI secretion system ATPase TssH	K4FB40	Cronobacter_phage	1.6e-92	31.6
WP_002210014.1\|3885272_3885764_-	Hcp family type VI secretion system effector	NA	NA	NA	NA
WP_002228049.1\|3885767_3887504_-	OmpA family protein	NA	NA	NA	NA
WP_002210015.1\|3887503_3888190_-	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_002211664.1\|3888186_3889539_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_002215896.1\|3889550_3891095_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_002211662.1\|3891137_3891638_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_002215900.1\|3893913_3894309_-	lipoprotein	NA	NA	NA	NA
WP_002215902.1\|3894759_3895410_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_13

4230023 : 4292459

uncultured_Mediterranean_phage(18.18%)

tail,protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002216203.1\|4230023_4230539_-\|protease	ClpXP protease specificity-enhancing factor	A0A1S5R3H3	Pseudomonas_phage	3.6e-28	55.6
WP_002210135.1\|4230544_4231186_-	stringent starvation protein A	NA	NA	NA	NA
WP_002230558.1\|4231365_4231563_+	hypothetical protein	NA	NA	NA	NA
WP_002210133.1\|4231559_4231952_-	30S ribosomal protein S9	NA	NA	NA	NA
WP_002210132.1\|4231966_4232395_-	50S ribosomal protein L13	NA	NA	NA	NA
WP_002210131.1\|4232708_4233836_-	cell division protein ZapE	NA	NA	NA	NA
WP_002210130.1\|4234059_4234464_+	DUF1043 family protein	NA	NA	NA	NA
WP_002218066.1\|4234734_4236108_+\|protease	serine endoprotease DegQ	A0A1B1IT49	uncultured_Mediterranean_phage	7.4e-20	28.2
WP_002213775.1\|4236224_4236683_-\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002210128.1\|4236908_4237997_+	outer membrane-stress sensor serine endopeptidase DegS	A0A1B1IRD3	uncultured_Mediterranean_phage	2.1e-09	31.8
WP_002210127.1\|4238177_4239440_-	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_002210126.1\|4239593_4239848_-	BolA family iron metabolism protein IbaG	NA	NA	NA	NA
WP_002210125.1\|4239994_4240297_-	lipid asymmetry maintenance protein MlaB	NA	NA	NA	NA
WP_002210124.1\|4240332_4240956_-	phospholipid-binding protein MlaC	NA	NA	NA	NA
WP_002210123.1\|4240968_4241526_-	outer membrane lipid asymmetry maintenance protein MlaD	NA	NA	NA	NA
WP_002210122.1\|4241530_4242313_-	lipid asymmetry maintenance ABC transporter permease subunit MlaE	NA	NA	NA	NA
WP_002210121.1\|4242530_4243349_-	phospholipid ABC transporter ATP-binding protein MlaF	G3M9Y6	Bacillus_virus	2.2e-19	31.7
WP_002210120.1\|4243613_4244588_+	calcium/sodium antiporter	NA	NA	NA	NA
WP_002210119.1\|4244698_4245685_+	arabinose-5-phosphate isomerase KdsD	A0A2P0VNK5	Tetraselmis_virus	6.0e-40	30.8
WP_002228203.1\|4245933_4246497_+	3-deoxy-manno-octulosonate-8-phosphatase KdsC	A0A140XBD6	Dickeya_phage	9.6e-59	83.0
WP_002218352.1\|4246493_4247057_+	LPS export ABC transporter periplasmic protein LptC	NA	NA	NA	NA
WP_002210117.1\|4247040_4247586_+	lipopolysaccharide ABC transporter substrate-binding protein LptA	NA	NA	NA	NA
WP_002210116.1\|4247592_4248318_+	LPS export ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.4e-22	28.4
WP_002210115.1\|4248379_4249813_+	RNA polymerase factor sigma-54	NA	NA	NA	NA
WP_002213952.1\|4250241_4250724_+	PTS IIA-like nitrogen regulatory protein PtsN	NA	NA	NA	NA
WP_002210113.1\|4251029_4251884_+	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	3.2e-05	30.0
WP_002210112.1\|4251880_4252153_+	PTS phosphocarrier protein NPr	NA	NA	NA	NA
WP_002210111.1\|4252490_4253426_+	aspartate carbamoyltransferase	M1HWF9	Paramecium_bursaria_Chlorella_virus	1.5e-48	38.5
WP_002210110.1\|4253437_4253902_+	aspartate carbamoyltransferase regulatory subunit	NA	NA	NA	NA
WP_002210109.1\|4254039_4254426_+	2-iminobutanoate/2-iminopropanoate deaminase	NA	NA	NA	NA
WP_002210107.1\|4254724_4255201_+	hypothetical protein	NA	NA	NA	NA
WP_002210106.1\|4255434_4256388_+	HTH-type transcriptional regulator TreR	NA	NA	NA	NA
WP_002215779.1\|4256798_4258214_+	PTS trehalose transporter subunit IIBC	NA	NA	NA	NA
WP_002210104.1\|4258308_4259976_+	alpha,alpha-phosphotrehalase	NA	NA	NA	NA
WP_002210103.1\|4260328_4260739_+	nucleoside diphosphate kinase regulator	NA	NA	NA	NA
WP_002210102.1\|4260970_4261357_-	cytochrome b562	NA	NA	NA	NA
WP_011055205.1\|4261564_4262209_-	hypothetical protein	A0A1B0VBK8	Salmonella_phage	3.4e-52	49.0
WP_002210100.1\|4262457_4263798_-\|protease	metalloprotease PmbA	NA	NA	NA	NA
WP_002210099.1\|4263978_4264527_+	ribosome-associated protein	NA	NA	NA	NA
WP_002210098.1\|4264638_4264920_-	ribonuclease inhibitor	NA	NA	NA	NA
WP_002214288.1\|4264924_4265398_-	ribonuclease Ba	NA	NA	NA	NA
WP_002210095.1\|4267327_4269283_-	p-hydroxybenzoic acid efflux pump subunit AaeB	NA	NA	NA	NA
WP_002210094.1\|4269284_4270220_-	p-hydroxybenzoic acid efflux pump subunit AaeA	NA	NA	NA	NA
WP_002210093.1\|4270227_4270431_-	AaeX family protein	NA	NA	NA	NA
WP_002210092.1\|4270733_4271645_+	HTH-type transcriptional activator AaeR	NA	NA	NA	NA
WP_002214297.1\|4271905_4272772_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002210090.1\|4273007_4275509_+	toxin	NA	NA	NA	NA
WP_002220204.1\|4275549_4279143_+\|tail	phage tail tape measure protein	NA	NA	NA	NA
WP_002210089.1\|4279199_4283690_+	toxin	NA	NA	NA	NA
WP_002214300.1\|4283823_4284126_+	hypothetical protein	NA	NA	NA	NA
WP_002210087.1\|4284138_4284540_+	M15 family metallopeptidase	A0A249XWK9	Proteus_phage	3.6e-36	61.0
WP_002210086.1\|4284536_4284896_+	DUF2570 domain-containing protein	NA	NA	NA	NA
WP_002210084.1\|4285096_4287928_+	RHS repeat protein	NA	NA	NA	NA
WP_002210083.1\|4287952_4290811_+	RHS repeat protein	NA	NA	NA	NA
WP_002210082.1\|4291013_4292459_-\|protease	metalloprotease TldD	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr_ID: NZ_CP045154.1|WP_002214494.1|2577045_2577402_+|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_CP045154.1|WP_002214494.1|2577045_2577402_+|hypothetical-protein

2577045_2577402_+

118 aa aa

HTH_GNTR

Identity	Hit_domain_coverage
0.4166666666666667	1.0

2521142-2621628

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP045154_2	Orphan	2.8\|1429964\|32\|NZ_CP045154\|CRISPRCasFinder,CRT	1429964-1429995	32	2549031-2549062	0

1. spacer 2.8|1429964|32|NZ_CP045154|CRISPRCasFinder,CRT matches to NZ_CP045154 position: 2549031-2549062, mismatch: 0

agactgatgcaagatggcggtatgcgtacaga	CRISPR spacer
agactgatgcaagatggcggtatgcgtacaga	Protospacer
********************************

3. NZ_CP045156

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

43798 : 66770

Enterobacteria_phage(50.0%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002213006.1\|43798_44767_-\|protease	T3SS effector cysteine protease YopT	NA	NA	NA	NA
WP_002213007.1\|45266_45815_+	hypothetical protein	NA	NA	NA	NA
WP_002229770.1\|46412_47042_+	hypothetical protein	NA	NA	NA	NA
WP_002220902.1\|49053_50220_+	plasmid-partitioning protein SopA	Q7Y3Y6	Yersinia_phage	3.5e-196	85.3
WP_002213354.1\|50216_51182_+	ParB/RepB/Spo0J family plasmid partition protein	Q7Y3Y7	Yersinia_phage	3.1e-89	56.6
WP_154020274.1\|51341_51578_+	hypothetical protein	NA	NA	NA	NA
WP_002224342.1\|52443_52686_+	type II toxin-antitoxin system ParD family antitoxin	NA	NA	NA	NA
WP_002213360.1\|52678_52978_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_002229754.1\|53117_53777_-	type III secretion system effector GTPase activator YopE	NA	NA	NA	NA
WP_002213403.1\|53970_54363_+	YopE transcriptional regulator YerA	NA	NA	NA	NA
WP_002220893.1\|55172_56345_+\|transposase	IS21 family transposase	U5N3F9	Enterobacteria_phage	1.6e-220	95.4
WP_002213267.1\|57119_57545_+	type III secretion system chaperone SycH	NA	NA	NA	NA
WP_086016640.1\|57692_58792_-\|transposase	IS3-like element ISYpe1 family transposase	S5WIU1	Leptospira_phage	1.4e-45	38.5
WP_002229829.1\|58891_59221_-	hypothetical protein	NA	NA	NA	NA
WP_002224338.1\|59359_59824_-	hypothetical protein	NA	NA	NA	NA
WP_002213258.1\|59842_60394_-	recombinase family protein	Q1MVP4	Enterobacteria_phage	5.9e-77	80.3
WP_002213256.1\|60557_62873_+\|transposase	Tn3 family transposase	Q1MVP5	Enterobacteria_phage	1.0e-279	51.6
WP_042469136.1\|65484_65754_-\|transposase	transposase	NA	NA	NA	NA
WP_002213246.1\|65822_66281_+	hypothetical protein	NA	NA	NA	NA
WP_002213244.1\|66452_66770_+\|transposase	transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP045155

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP045154

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information

3. NZ_CP045156

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection