CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP045225	Clostridioides difficile strain TW11 plasmid p_TW11, complete sequence	0 crisprs	NA	0	0	0	0
NZ_CP045224	Clostridioides difficile strain TW11 chromosome, complete genome	15 crisprs	cas14j,WYL,csa3,cas6,cas8b2,cas7,cas5,cas3,cas4,cas1,cas2,DEDDh,cas8b1,cas7b,cas14k,RT,DinG	5	108	8	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP045224_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045224_1

337030-338120

TypeV

Consensus_repeat	Method
GGAGNAACAGGNNCAACAGG	CRT

16 spacers

cas14j

The CRISPR arrays of NZ_CP045224_1

>merge|NZ_CP045224|1|337030-338120|CRT
GGTGCAACCGGAGCAGATGGAGTAACAGGCCCAACAGGCCCAACCGGAGCAACCGGAGCAAATGGAATAACAGGTCCAACAGGTGCAACCGGAGCAACAGGATTTGGAGTGACAGGTCCAACAGGCCCAACCGGAGCAACAGGAGTAGGAGTAACAGGAGCAACAGGATTAATAGGCCCAACCGGAGCAACAGGAACACCTGGAGTAACAGGTCCAACAGGGGCAGTAGGAGCAACAGGAATAGGAATAACAGGTCCAACAGGTCCAACCGGAGCAACCGGAGCAGATGGAGCAACAGGGGCAACGGGCCCAACAGGAGCAACAGGGACAACCGGAGCAGATGGAGTAACAGGTCCAACAGGTGCAACTGGAGCAACAGGATTTGGAGTGACAGGTCCAACCGGCCCAACCGGAGCAACAGGAGTAGGAGTAACAGGAGCAACAGGGTTAATAGGTCCAACAGGCCCAACCGGAGCAACAGGGTTAATAGGTCCAACAGGAGTAACAGGGGCAACTGGAGCAGATGGAGTAACAGGCCCAACAGGTCCAACCGGAGCAACCGGAGCAGATGGAGCAACCGGAGTAACAGGTCCAACAGGTGCAACAGGGGCAACCGGAGCAGATGGATTAGTAGGTCCAACAGGGGCAACCGGAGCAACTGGAGCAGATGGAGTAACAGGCCCAACAGGGGCAACCGGAGCAACCGGAGTAGGAGTAACAGGAGCAACAGGGGCAACTGGAGCAACTGGCCCAACCGGAGCAGATGGATTAGTAGGTCCAACCGGAGCAACAGGAAATACCGGAGCAGATGGAGTAGCAGGTCCAACAGGAGCAACAGGAGCAACAGGAAATACTGGAGCAGATGGAGCAACAGGTCCAACAGGAGCAACAGGAAATACCGGAGCAGATGGAGCAACAGGCCCAACAGGTCCAACAGGGGCAACCGGAGTAGCAGGAGTAACTGGGGCAACAGGCCCAACAGGAGCAACAGGGGCAACAGGAGCAGATGGGGCAACAGGCCCAACAGGAGCAACAGGGGCAACAGGAGCAGATGGATTAGTAGGTCCAACAGGGGCAACAGGAGCAACAGG

>NZ_CP045224|1|1|337030-338120|CRT
GGTGCAACCGGAGCAGATGG	AGTAACAGGCCCAACAGGCCCAACCGGAGCAACCGGAGCAAATGGAATAACAGGTCCAACA
GGTGCAACCGGAGCAACAGG	ATTTGGAGTGACAGGTCCAACAGGCCCAACCGGAGCAACAGGAGTA
GGAGTAACAGGAGCAACAGG	ATTAATAGGCCCAACCGGAGCAACAGGAACACCT
GGAGTAACAGGTCCAACAGG	GGCAGTAGGAGCAACAGGAATA
GGAATAACAGGTCCAACAGG	TCCAACCGGAGCAACCGGAGCAGATGGAGCAACA
GGGGCAACGGGCCCAACAGG	AGCAACAGGGACAACCGGAGCAGAT
GGAGTAACAGGTCCAACAGG	TGCAACTGGAGCAACAGGATTT
GGAGTGACAGGTCCAACCGG	CCCAACCGGAGCAACAGGAGTA
GGAGTAACAGGAGCAACAGG	GTTAATAGGTCCAACAGGCCCAACCGGAGCAACAGGGTTAATAGGTCCAACA
GGAGTAACAGGGGCAACTGG	AGCAGATGGAGTAACAGGCCCAACAGGTCCAACCGGAGCAACCGGAGCAGATGGAGCAACC
GGAGTAACAGGTCCAACAGG	TGCAACAGGGGCAACCGGAGCAGATGGATTAGTAGGTCCAACAGGGGCAACCGGAGCAACTGGAGCAGAT
GGAGTAACAGGCCCAACAGG	GGCAACCGGAGCAACCGGAGTAGGAGTAACAGGAGCAACAGGGGCAACT
GGAGCAACTGGCCCAACCGG	AGCAGATGGATTAGTAGGTCCAACCGGAGCAACAGGAAATACCGGAGCAGATGGAGTAGCAGGTCCAACA
GGAGCAACAGGAGCAACAGG	AAATACTGGAGCAGATGGAGCAACAGGTCCAACAGGAGCAACAGGAAATACCGGAGCAGAT
GGAGCAACAGGCCCAACAGG	TCCAACAGGGGCAACCGGAGTAGCAGGAGTAACTGGGGCAACAGGCCCAACAGGAGCAACAGGGGCAACAGGAGCAGAT
GGGGCAACAGGCCCAACAGG	AGCAACAGGGGCAACAGGAGCAGATGGATTAGTAGGTCCAACA
GGGGCAACAGGAGCAACAGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045224.1\|WP_003417027.1\|339919_340198_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|337191
NZ_CP045224.1\|WP_003417016.1\|331730_332399_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225917
NZ_CP045224.1\|WP_003417008.1\|327395_328934_-\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|223562
NZ_CP045224.1\|WP_003417012.1\|330546_330870_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224647
NZ_CP045224.1\|WP_032510113.1\|334151_334610_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|225117
NZ_CP045224.1\|WP_003417026.1\|338853_339615_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224516
NZ_CP045224.1\|WP_003417031.1\|344943_346002_+\|flippase-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|377103
NZ_CP045224.1\|WP_003417034.1\|348445_349279_+\|formate-dehydrogenase-accessory-sulfurtransferase-FdhD	unknown	unknown	gnl\|CDD\|376873
NZ_CP045224.1\|WP_077699411.1\|346252_348397_+\|formate-dehydrogenase-subunit-alpha	unknown	unknown	gnl\|CDD\|130652
NZ_CP045224.1\|WP_009906406.1\|340492_341068_+\|DUF1062-domain-containing-protein	unknown	unknown	gnl\|CDD\|368855
NZ_CP045224.1\|WP_003417030.1\|344073_344733_+\|two-component-system-response-regulator-CprR	unknown	unknown	gnl\|CDD\|223816
NZ_CP045224.1\|WP_003417018.1\|332513_333929_+\|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|224089
NZ_CP045224.1\|WP_003417022.1\|334606_335191_+\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	unknown	unknown	gnl\|CDD\|178955
NZ_CP045224.1\|WP_003417024.1\|335493_336570_+\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|133005
NZ_CP045224.1\|WP_003417010.1\|330215_330542_+\|DJ-1/PfpI-family-protein	unknown	unknown	gnl\|CDD\|153229
NZ_CP045224.1\|WP_003417037.1\|349499_350051_+\|4Fe-4S-dicluster-domain-containing-protein	unknown	unknown	gnl\|CDD\|319876
NZ_CP045224.1\|WP_003417014.1\|331021_331540_+\|nitroreductase-family-protein	unknown	unknown	gnl\|CDD\|380330
NZ_CP045224.1\|WP_041160426.1\|341717_342836_+\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	cas14j	-	gnl\|CDD\|223747
NZ_CP045224.1\|WP_003417029.1\|343134_343764_-\|DUF3786-domain-containing-protein	unknown	unknown	gnl\|CDD\|372241
NZ_CP045224.1\|WP_032510114.1\|326405_327119_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816

Protein	Function_ID	Function_description	E-value
NZ_CP045224.1\|WP_003417027.1\|339919_340198_+\|hypothetical-protein	gnl\|CDD\|337191	pfam08765, Mor, Mor transcription activator family. Mor (Middle operon regulator) is a sequence specific DNA binding protein. It mediates transcription activation through its interactions with the C-terminal domains of the alpha and sigma subunits of bacterial RNA polymerase. The N terminal region of Mor is the dimerization region, and the C terminal contains a helix-turn-helix motif which binds DNA.	0.000564406
NZ_CP045224.1\|WP_003417016.1\|331730_332399_-\|hypothetical-protein	gnl\|CDD\|225917	COG3382, COG3382, Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only].	3.2873e-13
NZ_CP045224.1\|WP_003417008.1\|327395_328934_-\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	1.52176e-162
NZ_CP045224.1\|WP_003417012.1\|330546_330870_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	2.63757e-45
NZ_CP045224.1\|WP_032510113.1\|334151_334610_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	3.174e-29
NZ_CP045224.1\|WP_003417026.1\|338853_339615_+\|hypothetical-protein	gnl\|CDD\|224516	COG1600, COG1600, Uncharacterized Fe-S protein [Energy production and conversion].	2.20403e-18
NZ_CP045224.1\|WP_003417031.1\|344943_346002_+\|flippase-like-domain-containing-protein	gnl\|CDD\|377103	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region. LPG_synthase_TM is the N-terminal region of this family of bacterial phosphatidylglycerol lysyltransferases. The function of the family is to add lysyl groups to membrane lipids, and this region is the transmembrane domain of 7xTMs. In order to counteract attack by membrane-damaging external cationic antimicrobial molecules - from host immune systems, bacteriocins, defencins, etc - bacteria modify their anionic membrane phosphatidylglycerol with positively-charged L-lysine; this results in repulsion of the foreign cationic peptides.	7.28111e-17
NZ_CP045224.1\|WP_003417034.1\|348445_349279_+\|formate-dehydrogenase-accessory-sulfurtransferase-FdhD	gnl\|CDD\|376873	pfam02634, FdhD-NarQ, FdhD/NarQ family. A pan-bacterial lineage of proteins. Nitrate assimilation protein, NarQ, and FdhD are required for formate dehydrogenase activity. Structurally, they possess a deaminase fold with a characteristic binding pocket, suggesting that they might bind a nucleotide or related molecule allosterically to regulate the formate dehydrogenase catalytic subunit.	9.67487e-88
NZ_CP045224.1\|WP_077699411.1\|346252_348397_+\|formate-dehydrogenase-subunit-alpha	gnl\|CDD\|130652	TIGR01591, Formate_dehydrogenase_subunit_alpha, formate dehydrogenase, alpha subunit, archaeal-type. This model describes a subset of formate dehydrogenase alpha chains found mainly archaea but also in alpha and gamma proteobacteria and a small number of gram positive bacteria. The alpha chain contains domains for molybdopterin dinucleotide binding and molybdopterin oxidoreductase (pfam01568 and pfam00384, respectively). The holo-enzyme also contains beta and gamma subunits. The enzyme catalyzes the oxidation of formate (produced from pyruvate during anaerobic growth) to carbon dioxide with the concomitant release of two electrons and two protons. The enzyme's purpose is to allow growth on formate in some circumstances and, in the case of FdhH in gamma proteobacteria, to pass electrons to hydrogenase (by which process acid is neutralized). This model is well-defined, with only a single fragmentary sequence falling between trusted and noise. The alpha subunit of a version of nitrate reductase is closely related.	0
NZ_CP045224.1\|WP_009906406.1\|340492_341068_+\|DUF1062-domain-containing-protein	gnl\|CDD\|368855	pfam06353, DUF1062, Protein of unknown function (DUF1062). This family consists of several hypothetical bacterial proteins of unknown function.	1.7332e-57
NZ_CP045224.1\|WP_003417030.1\|344073_344733_+\|two-component-system-response-regulator-CprR	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.82528e-71
NZ_CP045224.1\|WP_003417018.1\|332513_333929_+\|PLP-dependent-aminotransferase-family-protein	gnl\|CDD\|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	2.26648e-130
NZ_CP045224.1\|WP_003417022.1\|334606_335191_+\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	2.4028e-134
NZ_CP045224.1\|WP_003417024.1\|335493_336570_+\|glycosyltransferase-family-2-protein	gnl\|CDD\|133005	cd02511, Beta4Glucosyltransferase, UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide. UDP-glucose: lipooligosaccharide (LOS) beta-1-4-glucosyltransferase catalyzes the addition of the first residue, glucose, of the lacto-N-neotetrase structure to HepI of the LOS inner core. LOS is the major constituent of the outer leaflet of the outer membrane of gram-positive bacteria. It consists of a short oligosaccharide chain of variable composition (alpha chain) attached to a branched inner core which is lined in turn to lipid A. Beta 1,4 glucosyltransferase is required to attach the alpha chain to the inner core.	1.42191e-45
NZ_CP045224.1\|WP_003417010.1\|330215_330542_+\|DJ-1/PfpI-family-protein	gnl\|CDD\|153229	cd03135, GATase1_DJ-1, Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1. Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1. DJ-1 is involved in multiple physiological processes including cancer, Parkinson's disease and male fertility. It is unclear how DJ-1 functions in these. DJ-1 has been shown to possess chaperone activity. DJ-1 is preferentially expressed in the testis and moderately in other tissues; it is induced together with genes involved in oxidative stress response. The Drosophila homologue (DJ-1A) plays an essential role in oxidative stress response and neuronal maintenance. Inhibition of DJ-1A function through RNAi, results in the cellular accumulation of reactive oxygen species, organismal hypersensitivity to oxidative stress, and dysfunction and degeneration of dopaminergic and photoreceptor neurons. DJ-1 has lacks enzymatic activity and the catalytic triad of typical GATase1 domains, however it does contain the highly conserved cysteine located at the nucelophile elbow region typical of these domains. This cysteine been proposed to be a site of regulation of DJ-1 activity by oxidation. DJ-1 is a dimeric enzyme.	3.61604e-18
NZ_CP045224.1\|WP_003417037.1\|349499_350051_+\|4Fe-4S-dicluster-domain-containing-protein	gnl\|CDD\|319876	cd10554, HycB_like, HycB, HydN and similar proteins. This family includes HycB, the FeS subunit of a membrane-associated formate hydrogenlyase system (FHL-1) in Escherichia coli that breaks down formate, produced during anaerobic fermentation, to H2 and CO2. FHL-1 consists of formate dehydrogenase H (FDH-H) and the hydrogenase 3 complex (Hyd-3). HycB is thought to code for the [4Fe-4S] ferredoxin subunit of hydrogenase 3, which functions as an intermediate electron carrier protein between hydrogenase 3 and formate dehydrogenase. HydN codes for the [4Fe-4S] ferredoxin subunit of FDH-H; a hydN in-frame deletion mutation causes only weak reduction in hydrogenase activity, but loss of more than 60% of FDH-H activity. This pathway is only active at low pH and high formate concentrations, and is thought to provide a detoxification/de-acidification system countering the buildup of formate during fermentation.	6.62365e-66
NZ_CP045224.1\|WP_003417014.1\|331021_331540_+\|nitroreductase-family-protein	gnl\|CDD\|380330	cd20609, nitroreductase, nitroreductase family protein. A subfamily of the nitroreductase family containing uncharacterized proteins. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer.often found to be homodimers.	6.17932e-93
NZ_CP045224.1\|WP_041160426.1\|341717_342836_+\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl\|CDD\|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	9.21493e-56
NZ_CP045224.1\|WP_003417029.1\|343134_343764_-\|DUF3786-domain-containing-protein	gnl\|CDD\|372241	pfam12654, DUF3786, Domain of unknown function (DUF3786). This presumed domain is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 201 and 257 amino acids in length. Some proteins also contains an iron-sulfur cluster.	6.49549e-62
NZ_CP045224.1\|WP_032510114.1\|326405_327119_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	7.1188e-78

>NZ_CP045224.1|WP_003417024.1|335493_336570_+|glycosyltransferase-family-2-protein
MITISLCMIVKNEEEVIGRCLECVKDIVDEIIIVDTGSTDSTKEIVSKYTDMVYDFEWIDDFSAARNFSFSKASKDYTMWLDADDIILEADREKLLKIKESLDTSIDIVMAKYNVSFDENGSPTLSYYRERLFKRSSNHKWVDPIHEVVPLSGEVFYSDIAISHKKLHRQDPLRNLRIFEKMISEGKVLEPRHQFYYSRELYYNAKYKEAIEGFTKFLDSSRGWIEDCISACRDLATCYYLINDEKSALYSLFRSFEFDEPRAEICCDIGKHMFDRQKYKEAIFWYKVALTRDKNDTNGGFKSNDCYGYIPYIQLSVCYDRLGESNKAIYYHEKTKEIKPNDSAVLHNENYFNKFKNS
>NZ_CP045224.1|WP_003417022.1|334606_335191_+|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP
MSLVPHVIEQTSQGERSYDIYSKLLKDRIIFIGEEINDAIASLVVAQLLFLESEDPDSDIIIYINSPGGSVTAGFAIYDTMNYVRCDVSTICIGMAASMSAFLLAGGTHGKRYALPNAEIMIHQPMGGAKGQATDVKIAVDNILKIKERLDRIFSENTGKSIEDIRRDTDRDNFMTALEAKEYGLIDYIMNRNE
>NZ_CP045224.1|WP_032510113.1|334151_334610_+|helix-turn-helix-domain-containing-protein
MEIIDYIEENLTENLNLDKIADIANYSKYHLHRMFTNIVGCTIHQYIQRRRLTEAARQLIFTDKYIIDIAITAGYSTHQSFTLAFRNLYKESPQVYRNKDEFYPIQQRFVLNLNHQIQSEKYISYANMNCKQRIDEINSYLNFNINCEVKVA
>NZ_CP045224.1|WP_003417018.1|332513_333929_+|PLP-dependent-aminotransferase-family-protein
MWITINRNSNISLSRQIYCEIKDMILNGSLKFEQKLPSSRTLSKELSVSRNTVLDAYNQLIAEGYLETRNGYGTIVAKGISGHKVDFKLNYIFRDEKDLHTNKQKNYIDFRSGVPELKLFPRKELSKLYKQILYDLSDSDFRYGSTAGVWVLRAEISKYLFRTRGIRCNPKNIMIVSGSTQGLSLISQLLYKSNKKVAVEDPIHKGLLKVISSIGYSVVGVKVDDKGINTNLIKSIKGISFVYTTPSHQYPLGGILPIQRRLELIKYATENGYYIIEDDYDSEFRYEGQPISSLYELNPNKVIYIGSFSKILSPAIRVGFILLPDNILESYKTLKMYSDVHTETILQHVLAEFIGNGGLEKYIFRMKKLYNRKRKYLIKVLNTEFKNEFKIKGEAAGLHIVAHFYNVKFTESLIHKIFEAGIKVYPIQQYAIEKILEYDHEIILGYAHLSFDEIEKGVKILSKIIHINQGT
>NZ_CP045224.1|WP_003417016.1|331730_332399_-|hypothetical-protein
MLEISHKVKEIYPNIKFGVMVINITHSKPNKENFLILKNSTIKNIIEKHPEYNRKEKIKTEPVSSYIKYYKKFKKTYPVLLQLESILLKSKGIPDVGVTIESMFLAELKNLLLTAGHDLDKIELPLKIDLANGSEHFYGIGAKEQILTKDDLFLSDNIGILSSILNGPDNRTAITKDTKNIMYFVYGPDKISEKQIQDHLNDIKYYISSAFPDLKINSIDIF
>NZ_CP045224.1|WP_003417014.1|331021_331540_+|nitroreductase-family-protein
MNFVELAKKRYSCRNYQDRKVEKEKLDKVLDVARIAPTGGNRQPQRLIVIQEKEGLNKLSKAANIYDAPLAILVCGDKEKVWTRPFDGKQLTDIDTSIVTDHMMLQATELGLASVWVCYFNPDIIREEFSLPDNLEPINILLMGYESKVADSPDRHEKTRVPLSEIVSYEIL
>NZ_CP045224.1|WP_003417012.1|330546_330870_-|helix-turn-helix-transcriptional-regulator
MKKCLDNYSCPIEATLALIGGKYKTLILWHLKDTILRFNELKKLIPKATPKMLTQQLRELESDGLIIRVVYPVVPPKVEYSLSDFGKSIIPILDSMCDWGSDYLEKL
>NZ_CP045224.1|WP_003417010.1|330215_330542_+|DJ-1/PfpI-family-protein
MSSYLNLIREFNLKEKIIAFICVSALLIGKSCVLKNRKATTYHLKNSKRQRQLSEFDVNVVNEPTVVNQNIITSYYTETAPHVAFKLLEMLISKKQLDEVKLAMGFKL
>NZ_CP045224.1|WP_003417008.1|327395_328934_-|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MSLLKVTNLSQCFMDKSLYEKANFDLFKGEHIGVVGQNGTGKSTLIKILLGEVIPDSGEIKWQPNINIGHLDQYAEINRDTTISLYLHTAFEELYKIEKEMNLLYQESAISGNEQHLIKASDYQEQLIANNFYSIDNEVNKIANGLGLDSIGMNRVVGELSGGQRAKVILAKLLLSNHEVLLLDEPTNFLDKEHVEWLSNYLNTFSGAFIVVSHDFDFLEKISTGILDIEFGMIKKYHGKYSEFLKQKLHLREDYIRRYQSQQKKIEKEEAFIRKNKAGVNSKIARGRQKQLDKIERIAPPGFTGKPNIKFSEIEISAQNALTVTNLEVGYYYSLLPKLNFSVDGGQKIVITGFNGIGKSTLLKTLVKDIPCISGDFQFSEQVKLAYYEQDLKWENPTKTPLQIVADKYPKLNTKEIRRHLARCGVKEEHVSRSVSTLSGGEQSKVKLCCMMLFPCNFLILDEPTNHFDAETKDALQNALKQFRGSIILVSHEEKFYKGWIDKVFNIEKQLV
>NZ_CP045224.1|WP_032510114.1|326405_327119_+|response-regulator-transcription-factor
MDTYFNKKILLVDDEKDIVDLIEEVLINDGFKNIIKAYNGLDAISLCKIACPDVVILDIMLPDIDGIEVCKKIREFSYCSILFLSSKNDDIDKILGLSSGGDDYITKPFSPREIVFRVKAQLRRQQYQSIVPSDSSVIKIGDITIDIEGNRVYKDRKEIELTGREYHLLSYMAQNVNKIIGKERLYEQVWGVYSSICDNTIMVHIRHIREKIEDNPSNPKILITVKGLGYKLVNRID
>NZ_CP045224.1|WP_003417026.1|338853_339615_+|hypothetical-protein
MKNKIETLMNNFVKDYHKFNSITTKWQELLFAYASAEDDMFQKLKSVVGTSHAMPKDFLKNGKTIITYFIPFDESINNSNIGGFECSEIWARAYIETNMLISNLNSYLCEELEKIGFDSYAIPGSYNFDSEKLVSDWSQRHVAFISGLGTFGLNNMLITEKGCCGRIGSIITSLELEPTKRPENEYCLYKHNNSCKKCVNKCVKEALKEDRFDRNKCYEMCTINEKKYTYIGGCDICGKCIVGVPCSVINPSR
>NZ_CP045224.1|WP_003417027.1|339919_340198_+|hypothetical-protein
MSYKKAIHILPEELLELIQEYVDGEYIYIPRKSNNKKEWGSNTSTREELAIRNMQIYEDYQVGYDLQYLSEKYYLSLKSIQRIVLQEKRKDI
>NZ_CP045224.1|WP_009906406.1|340492_341068_+|DUF1062-domain-containing-protein
MQKITWEVEYTSQLPVIRYCKKCGKKTEYVCSGLFRVNAQHKYLDIWLIYKCLNCDSTWNSTIYSRVNPNNLSPEVLEQFHTNDDNLANQYAMNIELLHRNGAEVGIPEYKIVGQEIDINDLTQIRIVSKYPSQLKVSTLLREKLGLSRKVFDEMLDCGTIKSVSGVDLRRSKLNYEIVLEVGKEKQKSSN
>NZ_CP045224.1|WP_041160426.1|341717_342836_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MIAVEKAYKFRMYPNKKQQELINKTFGCCRFVYNKYLAKRIDVYKNNKETFTYKQCSSDLTNLKKELKWLKEPDKFSLQNALKDLENAYEKFFKEKTGFPKFKSKKTNRFSYKTNFTNGNIMYCGQHIKLPKLGMVKIRDKQVPKGRILNATISKEPSGRYYVSLCCTDVDTEAFENTNNQIGLDLGIKEFCISSCGEFIENPKYLKKSLSKLAKLQRELSRKTIGSLNRNKARLKVARLQEHIANQRNDFLQKLSTKLIKENDIICIEDLQVKNMIRNHKLSRLISDVSWSEFIRQLEYKANWHGRQIVKVGKFFASSQICNKCGYKNEEVKDLNIRDWICPSCNETHDRDINASINILKEGLRLITIQNK
>NZ_CP045224.1|WP_003417029.1|343134_343764_-|DUF3786-domain-containing-protein
MDEKIRSSNYNVPFDYARKKFKELDPHTISNLSNISFNNDSNKFILNFFDRQYIIDYPSGEVWNDDGSICKNFELKILIIRYLTNAKGIPRTNKYVTFKEIPGGNVYYPNFLNRTLSRLSEVFTCQIDKYKLVMENMGAEKVDMGDLAYKFTYMGNTSMIFILWFGDDEFPPNSNILFDSNIIYYFNAEDLAVVPDTAIDAILNKINQL
>NZ_CP045224.1|WP_003417030.1|344073_344733_+|two-component-system-response-regulator-CprR
MSKILVIDDELDVLKLIENVLKRDGHEVKVISDIENAMDIEFNSFNLIILDVMMPKMDGFEVCKAIRNKVDCPILFLTAKNMESDIMYGLGIGADDYITKPFGVGELRARITAHLRRESREKKNLLTISNVQFNFLGKEVLIDGKKINFTKSEYLICEFLAKNKGQVFSKERIYESVYGFDGESDISTITEHVKNIRSKLKQYDIYTIETVWGIGYKWV
>NZ_CP045224.1|WP_003417031.1|344943_346002_+|flippase-like-domain-containing-protein
MDRLKSIRKSLLQYTFLFLLIGITIYLVFKTLDIKMLSNVMVMVDKKFLFIGALAIMCHIMLEGVVMKIIIESTHKVNIRFIGFKLAIMGFYYNLITPFASGSQPVQIYVLKKCKMPLSKASAVVTNKSIIFQIVVTFYCTILVLMNFAMLEKQMKMIMPLVFLGIAINSFVLIMIILVILNPQKIKYFMRITIKHLSKIKFLKFLDNKIESIESFIDDYSKAINFFAKNKKVLISTIIVTFIQLSAYFSVSFWIYKAFNLQGYSYIYILTLQAFLYMAISPIPTPGNVGANELAFFTIFKSVFPQPLMGYAVFLYGGFMYYLILIGSGIFTVITHYRMKNRIGRNIVLSEN
>NZ_CP045224.1|WP_077699411.1|346252_348397_+|formate-dehydrogenase-subunit-alpha
MEKKILTVCPYCGAGCQLYLVVKDNKILRAEPANGRTNQESLCLKGRYGWDFLNDPKILTPRLKKPMIRKQGVLEEVEWDEAINYAASRLNEIKEKYGPDSIMGTGSARGPGNEANYIMQKFMRATIGTNNVDHCARVUHAPSVAGLAYSLGSGAMSNSIPEIENADVLFIFGYNGADSHPIVANRIVKAKKNGAKLIVTDPRVTESARIADIHLPIKGGTNMVLVNAFGNVLIEEGLYNKEFVQNHTQGFDEYKEIVKPYTAKYAEKITGIPEELIRKAMREYAKGKKAMILYGMGVCQFGQAVDVVKGLASIALLTGNFGRESVGIGPVRGQNNVQGACDMGALPNVYPGYQNVTDDKIREKFEKAWGVKLSPNNGYSLTQVPDLVLKEKKLKAYYIFGEDPVQSDPDASEVREALDELEFVIVQDIFMNKTALHADVILPATSWGEHEGVYTCADRGFQLMRKAIEPQGDVKPDWQIISEISTAMGYPMNYKNTKEIWDELRQLCPSFLGATYEKIEAQGCVQWPCKSESMEDKGTMYLYEGQKFSTPNGKGNLFAAEWRPPMEVEDDEYPFSLCTVREVGHYSVRTMTGNCRTLSSLEDEPGRVQINSNDAKKLGIEDDELVRISSRRGSVITRATVTDRVKEGATYMTYQWWVGACNELTIANLDPISKTPEYKYCAVKLEKLEDQELAEKCVREEYKSLKDKMTATNI
>NZ_CP045224.1|WP_003417034.1|348445_349279_+|formate-dehydrogenase-accessory-sulfurtransferase-FdhD
MNNIYSKTKLQQNSKDKVFENSYSLVEHKYLNSFNVEVSKINEHEVSIDNEEIIAEYPLSFILNNKYINTFLCTPSNLEELIVGFLKTKGYIENKKSLLKFEINESERFAKVTIHEKQKNQNEQIIFLNSLDYITCAPVESNIKINYDTIYSIMDRNLNSSELFKNTGGVHSVSIFNFDKRIVTCEDVARHNAMDKAIGFCVLNDIALKDKIVAVSGRISLEMILKAAMTQIPIVVSKSAPTNLSIELSKKLNITLIGFVRGRRMNIYANPQRVIKK
>NZ_CP045224.1|WP_003417037.1|349499_350051_+|4Fe-4S-dicluster-domain-containing-protein
MKNKIGSFVIADPNKCTGCRACEVACFTMHNQHNNVGYTVGTVDIPVIPRLYLVKGDNFCMPIQCRHCEDAPCLNSCPQKAIIKENNIMSVNEEKCIGCKTCLLACPFGAIDLLPQYQDGKEVEQVILDENKKIAYKCDLCKDSEKIACISACPQEALKLVTPIDDKKAKNRQAALSLLLTNK

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Crispr_ID: NZ_CP045224_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045224_2

454359-455366

Orphan

Consensus_repeat	Method
NCAACAGGNCCAACNGGA	CRT

15 spacers

The CRISPR arrays of NZ_CP045224_2

>merge|NZ_CP045224|2|454359-455366|CRT
CCAACAGGTCCAACAGGTCCAACAGGTGCTACTGGTCCAACGGGTCCGACTGGACCTAGAGGTGCAACCGGAGCAACGGGAGCAAATGGAATAACAGGTCCAACAGGAAACACAGGAGCAACAGGAGCGAATGGAATAACAGGTCCAACAGGAAATATGGGAGCGACTGGACCAAATGGAGCAACAGGTTCTACAGGTCCAACCGGAGCAACGGGAGCAACGGGAGCAAATGGAATAACAGGTCCAACAGGAAATACGGGAGCAACGGGAGCAAATGGAATAACAGGTCCAACAGGAAACAAAGGAGCAACGGGAGCAAATGGAATAACAGGTTCTACAGGTCCAACAGGAAATACAGGAGCAACCGGGGCAAATGGAATAACAGGTCCAACAGGAAATACGGGAGCAACCGGAGCAACAGGTCCAACTGGACTAACCGGAGCAACAGGGGCAACTGGAGCAAATGGAATAACAGGTCCAACAGGAAATACAGGAGCAACGGGAGCAAATGGAGTAACAGGTTCTACAGGTCCAACAGGAAGTACAGGAGCAACAGGCCCAACCGGAGCAGTAGGAGCAACCGGAGCAAATGGAGTGACAGGGGCAACAGGTCCAATAGGAGCAACAGGTCCAACTGGAGCAGATGGAGAGGTAGGTCCAACAGGAGCAGTAGGAGCAACAGGTCCAGATGGAGTAATAGGTCCAACAGGCCCAACGGGAGCAACCGGAGCAACTGGAGCAAATGGTTTGGTAGGCCCAACAGGCCCAACGGGAGCAACCGGAGCAAATGGTTTGGTAGGTCCAACAGGCCCAACGGGAGCAACCGGAGTAGCTGGGGCAATAGGTCCAACCGGAACAGTAGGAGCAACAGGCCCAACTGGAGCAGATGGAGCAGTAGGTCCAACCGGAGCGACAGGAGCGACAGGGGCAAATGGAGCAACAGGTCCAACCGGAGCAGTAGGAGCAACCGGAGCAACGGGAGTAGCAGGTCCAATAGGTCCAACAGGT

>NZ_CP045224|2|2|454359-455366|CRT
CCAACAGGTCCAACAGGT	CCAACAGGTGCTACTGGTCCAACGGGTCCGACTGGACCTAGAGGTGCAACCGGAGCAACGGGAGCAAATGGA
ATAACAGGTCCAACAGGA	AACACAGGAGCAACAGGAGCGAATGGAATAACAGGTCCAACAGGAAATATGGGAGCGACTGGACCAAATGGAGCAACAGGT
TCTACAGGTCCAACCGGA	GCAACGGGAGCAACGGGAGCAAATGGAATAACAGGTCCAACAGGAAATACGGGAGCAACGGGAGCAAATGGA
ATAACAGGTCCAACAGGA	AACAAAGGAGCAACGGGAGCAAATGGAATAACAGGTTCTACAGGTCCAACAGGAAATACAGGAGCAACCGGGGCAAATGGA
ATAACAGGTCCAACAGGA	AATACGGGAGCAACCGGAGCAACAGGTCCAACTGGACTAACCGGAGCAACAGGGGCAACTGGAGCAAATGGA
ATAACAGGTCCAACAGGA	AATACAGGAGCAACGGGAGCAAATGGAGTAACAGGTTCTACAGGTCCAACAGGAAGTACAGGA
GCAACAGGCCCAACCGGA	GCAGTAGGAGCAACCGGAGCAAATGGAGTGACAGGG
GCAACAGGTCCAATAGGA	GCAACAGGTCCAACTGGAGCAGATGGAGAGGTAGGT
CCAACAGGAGCAGTAGGA	GCAACAGGTCCAGATGGAGTAATAGGT
CCAACAGGCCCAACGGGA	GCAACCGGAGCAACTGGAGCAAATGGTTTGGTAGGC
CCAACAGGCCCAACGGGA	GCAACCGGAGCAAATGGTTTGGTAGGT
CCAACAGGCCCAACGGGA	GCAACCGGAGTAGCTGGG
GCAATAGGTCCAACCGGA	ACAGTAGGAGCAACAGGCCCAACTGGAGCAGATGGA
GCAGTAGGTCCAACCGGA	GCGACAGGAGCGACAGGGGCAAATGGA
GCAACAGGTCCAACCGGA	GCAGTAGGAGCAACCGGAGCAACGGGAGTAGCAGGT
CCAATAGGTCCAACAGGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045224.1\|WP_003422077.1\|453420_453960_+\|hypoxanthine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|223707
NZ_CP045224.1\|WP_003422094.1\|444325_444793_+\|D-proline-reductase	unknown	unknown	gnl\|CDD\|275273
NZ_CP045224.1\|WP_003422090.1\|445311_446319_+\|proline-racemase	unknown	unknown	gnl\|CDD\|184427
NZ_CP045224.1\|WP_003422079.1\|451784_453092_+\|serine-dehydratase-subunit-alpha-family-protein	unknown	unknown	gnl\|CDD\|226206
NZ_CP045224.1\|WP_003422058.1\|464099_465293_+\|L-serine-ammonia-lyase	unknown	unknown	gnl\|CDD\|273233
NZ_CP045224.1\|WP_003422063.1\|460460_461348_-\|4-hydroxy-tetrahydrodipicolinate-synthase	unknown	unknown	gnl\|CDD\|235107
NZ_CP045224.1\|WP_003422064.1\|459643_460393_-\|4-hydroxy-tetrahydrodipicolinate-reductase	unknown	unknown	gnl\|CDD\|234595
NZ_CP045224.1\|WP_003422084.1\|448804_449374_+\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|225136
NZ_CP045224.1\|WP_003422061.1\|461464_462466_-\|aspartate-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|237845
NZ_CP045224.1\|WP_003422060.1\|462895_463777_-\|4-hydroxy-tetrahydrodipicolinate-synthase	unknown	unknown	gnl\|CDD\|235107
NZ_CP045224.1\|WP_003422088.1\|446438_447320_+\|TSUP-family-transporter	unknown	unknown	gnl\|CDD\|376667
NZ_CP045224.1\|WP_003422081.1\|449585_451361_+\|sigma-54-interacting-transcriptional-regulator	unknown	unknown	gnl\|CDD\|226350
NZ_CP045224.1\|WP_009906341.1\|457473_458463_+\|membrane-protein	unknown	unknown	gnl\|CDD\|259800
NZ_CP045224.1\|WP_003422070.1\|456275_457031_-\|4-hydroxy-tetrahydrodipicolinate-reductase	unknown	unknown	gnl\|CDD\|234595
NZ_CP045224.1\|WP_003422082.1\|449451_449589_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_003422066.1\|458745_459462_-\|2,3,4,5-tetrahydropyridine-2,6-dicarboxylate-N-acetyltransferase	unknown	unknown	gnl\|CDD\|132571
NZ_CP045224.1\|WP_009906336.1\|466746_466992_+\|small,-acid-soluble-spore-protein,-alpha/beta-type	unknown	unknown	gnl\|CDD\|365990
NZ_CP045224.1\|WP_003422057.1\|465497_466616_+\|N-acetyldiaminopimelate-deacetylase	unknown	unknown	gnl\|CDD\|349920
NZ_CP045224.1\|WP_003422086.1\|447985_448621_+\|single-stranded-DNA-binding-protein	unknown	unknown	gnl\|CDD\|235616
NZ_CP045224.1\|WP_003422092.1\|444809_445292_+\|D-proline-reductase-(dithiol)	unknown	unknown	gnl\|CDD\|275273

Protein	Function_ID	Function_description	E-value
NZ_CP045224.1\|WP_003422077.1\|453420_453960_+\|hypoxanthine-phosphoribosyltransferase	gnl\|CDD\|223707	COG0634, Hpt, Hypoxanthine-guanine phosphoribosyltransferase [Nucleotide transport and metabolism].	8.93252e-77
NZ_CP045224.1\|WP_003422094.1\|444325_444793_+\|D-proline-reductase	gnl\|CDD\|275273	TIGR04480, D-proline_reductase_PrdA_proprotein, D-proline reductase (dithiol), PrdA proprotein. Members of this family are the PrdA proprotein. The polypeptide undergoes an autocatalytic cleavage that creates two subunits, one with a Cys-derived pyruvoyl motiety critical for activity. The D-proline reductase complex also contains a subunit derived from the prdB gene. The complex acts on D-proline, which may be supplied from L-proline by an active proline racemase encoded nearby.	6.50378e-55
NZ_CP045224.1\|WP_003422090.1\|445311_446319_+\|proline-racemase	gnl\|CDD\|184427	PRK13969, PRK13969, proline racemase; Provisional.	0
NZ_CP045224.1\|WP_003422079.1\|451784_453092_+\|serine-dehydratase-subunit-alpha-family-protein	gnl\|CDD\|226206	COG3681, COG3681, L-cysteine desulfidase [Amino acid transport and metabolism].	2.38578e-106
NZ_CP045224.1\|WP_003422058.1\|464099_465293_+\|L-serine-ammonia-lyase	gnl\|CDD\|273233	TIGR00720, hypothetical_protein_NEICINOT_00681, L-serine dehydratase, iron-sulfur-dependent, single chain form. This enzyme is also called serine deaminase and L-serine dehydratase 1. L-serine ammonia-lyase converts serine into pyruvate in the gluconeogenesis pathway from serine. This enzyme is comprised of a single chain in Escherichia coli, Mycobacterium tuberculosis, and several other species, but has separate alpha and beta chains in Bacillus subtilis and related species. The beta and alpha chains are homologous to the N-terminal and C-terminal regions, respectively, but are rather deeply branched in a UPGMA tree. This enzyme requires iron and dithiothreitol for activation in vitro, and is a predicted 4Fe-4S protein. Escherichia coli Pseudomonas aeruginosa have two copies of this protein. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	6.67523e-139
NZ_CP045224.1\|WP_003422063.1\|460460_461348_-\|4-hydroxy-tetrahydrodipicolinate-synthase	gnl\|CDD\|235107	PRK03170, PRK03170, dihydrodipicolinate synthase; Provisional.	6.4792e-159
NZ_CP045224.1\|WP_003422084.1\|448804_449374_+\|methyltransferase-domain-containing-protein	gnl\|CDD\|225136	COG2226, UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism].	4.46184e-05
NZ_CP045224.1\|WP_003422061.1\|461464_462466_-\|aspartate-semialdehyde-dehydrogenase	gnl\|CDD\|237845	PRK14874, PRK14874, aspartate-semialdehyde dehydrogenase; Provisional.	0
NZ_CP045224.1\|WP_003422060.1\|462895_463777_-\|4-hydroxy-tetrahydrodipicolinate-synthase	gnl\|CDD\|235107	PRK03170, PRK03170, dihydrodipicolinate synthase; Provisional.	5.85003e-152
NZ_CP045224.1\|WP_003422088.1\|446438_447320_+\|TSUP-family-transporter	gnl\|CDD\|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	3.71323e-08
NZ_CP045224.1\|WP_003422081.1\|449585_451361_+\|sigma-54-interacting-transcriptional-regulator	gnl\|CDD\|226350	COG3829, RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms].	6.30268e-151
NZ_CP045224.1\|WP_009906341.1\|457473_458463_+\|membrane-protein	gnl\|CDD\|259800	cd03402, SPFH_like_u2, Uncharacterized family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily. This model summarizes an uncharacterized family of proteins similar to stomatin, prohibitin, flotillin, HflK/C (SPFH) and podocin. The conserved domain common to the SPFH superfamily has also been referred to as the Band 7 domain. Many superfamily members are associated with lipid rafts. Individual proteins of the SPFH superfamily may cluster to form membrane microdomains which may in turn recruit multiprotein complexes. Microdomains formed from flotillin proteins may in addition be dynamic units with their own regulatory functions. Flotillins have been implicated in signal transduction, vesicle trafficking, cytoskeleton rearrangement and are known to interact with a variety of proteins. Stomatin interacts with and regulates members of the degenerin/epithelia Na+ channel family in mechanosensory cells of Caenorhabditis elegans and vertebrate neurons and participates in trafficking of Glut1 glucose transporters. Prohibitin may act as a chaperone for the stabilization of mitochondrial proteins. Prokaryotic HflK/C plays a role in the decision between lysogenic and lytic cycle growth during lambda phage infection. Flotillins have been implicated in the progression of prion disease, in the pathogenesis of neurodegenerative diseases such as Parkinson's and Alzheimer's disease, and in cancer invasion and metastasis. Mutations in the podocin gene give rise to autosomal recessive steroid resistant nephritic syndrome.	1.88916e-128
NZ_CP045224.1\|WP_003422070.1\|456275_457031_-\|4-hydroxy-tetrahydrodipicolinate-reductase	gnl\|CDD\|234595	PRK00048, PRK00048, dihydrodipicolinate reductase; Provisional.	5.63811e-105
NZ_CP045224.1\|WP_003422064.1\|459643_460393_-\|4-hydroxy-tetrahydrodipicolinate-reductase	gnl\|CDD\|234595	PRK00048, PRK00048, dihydrodipicolinate reductase; Provisional.	1.28396e-104
NZ_CP045224.1\|WP_003422066.1\|458745_459462_-\|2,3,4,5-tetrahydropyridine-2,6-dicarboxylate-N-acetyltransferase	gnl\|CDD\|132571	TIGR03532, DapD_Ac, 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase. This enzyme is part of the diaminopimelate pathway of lysine biosynthesis. Alternate name: tetrahydrodipicolinate N-acetyltransferase. Note that IUBMB lists this alternate name as the accepted name. Unfortunately, the related succinyl transferase acting on the same substrate (EC:2.3.1.117, TIGR00695) uses the opposite standard. We have decided to give these two enzymes names which more clearly indicated that they act on the same substrate.	6.72494e-109
NZ_CP045224.1\|WP_009906336.1\|466746_466992_+\|small,-acid-soluble-spore-protein,-alpha/beta-type	gnl\|CDD\|365990	pfam00269, SASP, Small, acid-soluble spore proteins, alpha/beta type.	7.63487e-06
NZ_CP045224.1\|WP_003422057.1\|465497_466616_+\|N-acetyldiaminopimelate-deacetylase	gnl\|CDD\|349920	cd05670, M20_Acy1_YkuR-like, M20 Peptidase aminoacyclase-1 YkuR-like proteins, including YkuR and Ama/HipO/HyuC proteins. Peptidase M20 family, aminoacyclase-1 YkuR-like subfamily including YkuR and Ama/HipO/HyuC proteins, most of which have not been well characterized to date. N-terminal acetylation of proteins is a widespread and highly conserved process that is involved in the protection and stability of proteins. Several types of aminoacylases can be distinguished on the basis of substrate specificity; substrates include indoleacetic acid (IAA) N-conjugates of amino acids, N-acetyl-L-amino acids and aminobenzoylglutamate. ACY1 breaks down cytosolic aliphatic N-acyl-alpha-amino acids (except L-aspartate), especially N-acetyl-methionine and acetyl-glutamate into L-amino acids and an acyl group. However, ACY1 can also catalyze the reverse reaction, the synthesis of acetylated amino acids. ACY1 may also play a role in xenobiotic bioactivation as well as in the inter-organ processing of amino acid-conjugated xenobiotic derivatives (S-substituted-N-acetyl-L-cysteine). ACY1 appears to physically interact with Sphingosine kinase type 1 (SphK1) and may influence its physiological functions; SphK1 and its product sphingosine-1-phosphate have been shown to promote cell growth and inhibit apoptosis of tumor cells. Strong expression of the human gene and its mouse ortholog Acy1 in brain, liver, and kidney suggest a role of the enzyme in amino acid metabolism of these organs.	0
NZ_CP045224.1\|WP_003422086.1\|447985_448621_+\|single-stranded-DNA-binding-protein	gnl\|CDD\|235616	PRK05813, PRK05813, single-stranded DNA-binding protein; Provisional.	1.92637e-126
NZ_CP045224.1\|WP_003422092.1\|444809_445292_+\|D-proline-reductase-(dithiol)	gnl\|CDD\|275273	TIGR04480, D-proline_reductase_PrdA_proprotein, D-proline reductase (dithiol), PrdA proprotein. Members of this family are the PrdA proprotein. The polypeptide undergoes an autocatalytic cleavage that creates two subunits, one with a Cys-derived pyruvoyl motiety critical for activity. The D-proline reductase complex also contains a subunit derived from the prdB gene. The complex acts on D-proline, which may be supplied from L-proline by an active proline racemase encoded nearby.	3.06142e-33

>NZ_CP045224.1|WP_003422077.1|453420_453960_+|hypoxanthine-phosphoribosyltransferase
MDIETKKWEVLYSEEKIKDKLKELGAIIEKDYKDKNLMVVSLLKGSFIFCADLVRNINLPLRVNFMTTSSYGNNEESTGKVKVVSDVTTDIAGYDVLVVDDITDSALTMDFVLKHLKAKNPASLKCCVLLDKPSRRKVDLVPDYCGFEIEDKFVVGYGFDFGDYYRNVPYIFNVTDEDR
>NZ_CP045224.1|WP_003422079.1|451784_453092_+|serine-dehydratase-subunit-alpha-family-protein
MRDIRKELVEMLKAEVKPAVGCTEPVALALACAKAKELLGEEIVENRMLVSPSIYKNGMCVGIPGTERLGLKIAAALGIVGGHSENGLSVLETLTKEEVKIAEDYMDNTPLSITPADTREKVFIEVVLKGKNHIAKVRIRTKHDNFTFLEKDGEVLLDNEPKVSASNDSAEKVESLMDTVTIQELIKNVEGIDFKDIEFLLDGVKMNEEMAEYGLKQKTGIGVGYGIKKSIEEGLLGNDVINYAMMLTAGASDARMAGVKMPVMSSNGSGNHGLTAILPIVAYNKKFPQSDERLAKALAISHLVTGYIKNYTGRLSAVCGCGVAASTGATAGISWLMNGTEKQIEGAIENMIADLSGMICDGAKAGCALKLSSAASAAIQSAIIAKQDCFVPPLNGIVGSSVEQSIQNLGRVSDKGMSITDEIILNVMNDMNKVD
>NZ_CP045224.1|WP_003422081.1|449585_451361_+|sigma-54-interacting-transcriptional-regulator
MMIMIGLEYIKSDIQNIAEAIVSVLNIDVTIVNKDLFRIAGTGVYIDKIGEKVDKYTAFKKSLTEQITILIDDPKSSDICRECYKSGACVEFAEVCCPIICDGVSHGVIGLIAFTKEQAQIIENNKSGLINFLGKMADLISNKLKAQIKTYELELEKKKLETLLNNMDKAVVSIDVDGKIDKYNSKFKELFNIKDNITGKNIFVELDFIKKPSINNFKKDKSCSFFYKRYGYDSKGIYNINKIVLKNELKGYVIDFIDKRDAIKNYNKMNKDYRIKLENIIGESVAIRNSKKEALIASKSTSTVLITGESGTGKELFARAIHNHSNRVDNPFIAVNCAAIPDNLLESELFGYEEGAFTGAKKGGKLGMFEVAHKGSIFLDEIGDMSLHLQSKLLRVLQEKELNKIGSKSNVSIDVRIIAATNKDLEKMVQNGTFREDLYYRLNVIPIKLPSLKERKEDIPLIIKHMVKEYSKKLDKNVIDIDSRVVDAMMEYKWPGNIRELQNIIEYSVNMSSSSIITMNVIPQKIKNTSVEELEVRSDRIIPLDELEKIEIIKALNKYKDYKKDKELTAKALGISRATLYRKIEKYNIIS
>NZ_CP045224.1|WP_003422082.1|449451_449589_+|hypothetical-protein
MEINYELIIIVMLFVILMSIQFTLNKIYLILKEIRQILMLKKNKE
>NZ_CP045224.1|WP_003422084.1|448804_449374_+|methyltransferase-domain-containing-protein
MKSILCQINKQPVKAKYTSDELECFLDTIEYNVGDKILLVGHIGNLGKRLRGLGTSVTILENSNYEDVCYSLVYNENCNVVKGKLEFLPFDDNQFNKIIIVDQFNVITDCEKASSEIQRVLKGNGEVILEDLNLKNLKVKLNYLKHKFCGSVAKIHYPHEVFNIFSRLNFDGMIKESNKLKYIYVGKRR
>NZ_CP045224.1|WP_003422086.1|447985_448621_+|single-stranded-DNA-binding-protein
MIAVKDENNVVNLRGELDNKLEFSHEIFGEKFYNMKIKINRLSDSFDILPMTVSERLLQDIDLDKQNLVNVVGQLRSYNKTLNNKNRLVLTVFVREIKSIDEENKDPNSIFLDGYVCKEPVYRKTPLGREITDLLVAINRPYNKSDYIPSIVWGRNAKFAKNLKVGDRIQLWGRVQSREYEKKIDENNVVKKMAYEVSISKIKKLDENNNE
>NZ_CP045224.1|WP_003422088.1|446438_447320_+|TSUP-family-transporter
MVAILKALYVVFAAIFAVVFGKDVAKANKEGKLEEQSTPKVAVTGFITDFFDTLGIGSFAPTIAMSKALKLNIPDKKMPGTLNVAHTIPVVTEAFIFTSIIPVDGVTLVSMVVAAAVGSYIGAGIIAKMDERKIQLVMGVTLALTAILMLLGHPWVNVLPGGGNELGLTGVKLVIGVIGNFILGALMTAGIGLYAPGMAMVYFLGMSAKVAFPIVMGSCALLMPVASMKFIKEDAYTKKASVIIAICGLIGVFVAAYIVKTLPMDILKALVIVVIAYTSATMIMAANKNKKTA
>NZ_CP045224.1|WP_003422090.1|445311_446319_+|proline-racemase
MKFSRSIQAIDSHTAGEATRIVVGGIPNIKGNSMPEKKEYLEENLDYLRTAIMLEPRGHNDMFGSVMTQPCCPDADFGIIFMDGGGYLNMCGHGTIGAMTAAIETGVVPAVEPVTHVVMEAPAGIIRGDVTVVDGKAKEVSFLNVPAFLYKEGVEVDLPGVGTVKFDISFGGSFFAIIHASQLGLKIEPQNAGKLTELAMKLRDIINEKIEIQHPTLAHIKTVDLVEIYDEPTHPEATYKNVVIFGQGQVDRSPCGTGTSAKLATLHAKGELKVGEKFVYESILGTLFKGEIVEETKVADFNAVVPKITGSAYITGFNHFVIDEEDPLKHGFILK
>NZ_CP045224.1|WP_003422092.1|444809_445292_+|D-proline-reductase-(dithiol)
MSFVGISTSMKNTSLHIFRDPLLDLIDNDSDIDLLGVVVVGTSEHNEWKTFLATRLGRWIESLRPDGVIITLDMAGNQHIDFTNAIAEFVKSDIPTVGLTIMGVDGLVITNPYLDKATIIDYKKTTGYIETEVVGDNHMDEVDVKKALAFLKLKMRKDAK
>NZ_CP045224.1|WP_003422094.1|444325_444793_+|D-proline-reductase
MGIGPSTKETSLHHFRDPLLDIVESDKDVDLLGVIVVGTPDGNENKTFVGQRTAAWLEAMRVDGAIVSSDGWGNSHVDYANTFEEIGKRDIPVVGVTFNGTQAKFVVSNQYMDTIVDMNKSKEGIETEVVGENNTNEIDAKKALAFLKLKMRKHG
>NZ_CP045224.1|WP_003422070.1|456275_457031_-|4-hydroxy-tetrahydrodipicolinate-reductase
MLKVIISGYNGTMGRVLAECVKKDNELKLVCGVARSADEKSHHSDTKLYKTMTDVTEKADVIIDFSHHETLEPILSYALKNNTPVVLATTGYDESDLSKIEEASKNIPILLSSNTSLGVNILIKLVKDASKMLEGFDIEIIEKHHNRKEDAPSGTATMIANAIKEVLPESTNTHGRYGRDCKRKANEIGIHSIRGGNIISDHDVIFAGDNEVLTLSHHSQSDEVFANGSIVAAKFLVGKQSGLYKMSDILG
>NZ_CP045224.1|WP_009906341.1|457473_458463_+|membrane-protein
MLKEEKTYQEKEAKVFNGVAALIMIVLFLVVSIGIMVFGIVKLDSGFTGIGSLMLIFGLIFIVVDFILFFGLKMINPKEAIVLVLFGNYYGTIKKEGYYWVNPFCSAINPAASRINVSKSSSDEKVDISTNSRGKKVSLKTMTLNNEKQKVNDLLGNPIIIGVVVIWKVIDATKAVFNVDNYNTFLSIQCDSTIRNVSRLYPYDVSEDGDEKSLRGSSQEIADRLKDELQSRVDIAGIEVCEVRITHLSYAPEIAAAMLQRQQAEAIIAARKKIVEGAVSMVEMALTNLSENNVVTLDEERKAAMVSNLLVVLCGNKDAQPVVNSSSIY
>NZ_CP045224.1|WP_003422066.1|458745_459462_-|2,3,4,5-tetrahydropyridine-2,6-dicarboxylate-N-acetyltransferase
MVNLNDAYEIARYIKEVKKKTPVKVYVNTNSLHFQSTDKFKVFGCNGSYIFVGDYEDIMEVLDKHGNDIIDTHVEYDRRNSAIPLKNTLSEHARIEPGAIIRDMVTIEKNAVVMMGAVINIGAVIGEGSMVDMNAVIGARGTLGKNVHLGAGAVVAGVLEPPSATPVIVEDDVLIGANAVILEGVRIGKGAVVAAGAVVTTDVEAGAVVAGSPAKVIKMKDEKTADKTKLMEDLRNLD
>NZ_CP045224.1|WP_003422064.1|459643_460393_-|4-hydroxy-tetrahydrodipicolinate-reductase
MLKVIATGYDGKMGKILADTIREDSELELVCVAARGLDSYEDDLKIYEDMSTIVEEADVVIDFSHHSNLDNILSYVLKTKTPLVIATTGYNDEEMNKIHEAAKVIPVFQSYNMSLGVNVLVKLVKDAAKLLEGFDIEIIEKHHNRKVDAPSGTAVMIANAIKEVLPNVENNYGRYGRSAKRQPNEVGIHAIRGGNIVGEHDALFAGDNEVLTISHQAQSRGIFASGSIAAAKYLVKQKPGFYNMDSMLG
>NZ_CP045224.1|WP_003422063.1|460460_461348_-|4-hydroxy-tetrahydrodipicolinate-synthase
MIFKGSAVALVTPFTKDNKVDFDKLGELVEYQIANGTDAIVSCGTTGEANTMTDEEQLATIKYVVEKVNKRVPVIAGSGSNDTMHSVNLSQEAEKLGVDALLIITPYYNKANKAGLKRHFETIANSVKLPIILYNVPGRTCVNISPSLIVELAKIDNIVAVKEASGDLGQVAEIASLVPDDFAIYSGNDDTILPLLSLGGQGVISVLANVCPQETHDLVAKFFEGDIEGSRKLQLGMDALIAALFIEVNPIPVKTAMNLLGFNVGDLRLPLAEMDPANLEVLKKELVNFGLKVNA
>NZ_CP045224.1|WP_003422061.1|461464_462466_-|aspartate-semialdehyde-dehydrogenase
MKKVNVAIVGATGMVGRTFLKVLEERNFPIENLFLFSSSKSAGSKVMFCGKEYIVEELKETSFTDRGIQIALFSAGGSISEKYAPIAASNGILVVDNSSQWRMNPDVPLVVPEVNPEAIKNHKGIIANPNCSTIQAMVPLKALDDKYKIKRVVYSTYQAVSGSGVKGVEDLEKGMNGNPTGFYPHQISYNCLPHIDSFTENGYTKEEMKMVNETMKILDNYDLKITATTVRVPVKNGHSESINVEFNNPFELDDLVKTLEEAPGVVVVDNPAKNEYPTAVEFDDRDEVFVGRIRRDFSVDNGVNLWVVADNIRKGAATNAIQIAEMALSYDLV
>NZ_CP045224.1|WP_003422060.1|462895_463777_-|4-hydroxy-tetrahydrodipicolinate-synthase
MLFKGSAVALVTPFTEDNNVNFEKLGELIEYHIENDTDALVVCGTTGEATTMSESEIFAVIKYTVEKVNKRIPVIAGTGSNNTMLSVHMSQEAEKLGVDGLLIITPYYNKTNEKGLKLHFETIANSVKLPIILYNVPGRTKVNIKPSVVAELAKIDNIVAVKEASGDLAQVAEIAKLVPEDFAIYSGNDDTILPLLSLGGSGVISVLANICPKETHDLVAKFFEGDIEGSKKLQLDMDALIAALFIEVNPVPVKTAMNILGFNVGDLRLPLAEMEETNLNVLKHKLTNFGFKF
>NZ_CP045224.1|WP_003422058.1|464099_465293_+|L-serine-ammonia-lyase
MDTLKELFKIGSGPSSSHTMGPQRAAERFKNENPDAESFRAILYGSLAATGKGHLTDYIIEKTIAPKKVEIVWEEDIIKDFHPNGMKFEALDKDKNVTAEWTVYSVGGGTIAEEGQRNSKSNSIYHLDTMDEIVKWCKENNKTLVDFVLECEPKDIKDYIKTIKDAMRKSIDDGLSTDEIIPGKLLLKRRASTFYNAYKKDKSFSTLVYAYALAASEQNASGNIIVTAPTCGSAGVIPGIFFAMQDFYNYDDEKIIEALLVAGIIGNIIKTNASISGAEVGCQGEVGAACSMAAAAVAYLKGGTIDHIEYAAEIALEHHLGMTCDPVYGYVQIPCIERNAMAAQRAYDAANYALLTDGSHSVSLDQVVETMKETGIDMMDKYKETAKGGLAKHFFSC
>NZ_CP045224.1|WP_003422057.1|465497_466616_+|N-acetyldiaminopimelate-deacetylase
MREASYLQEQLYKHRKSLNPIAEIGRKEYKTSKYIRDYLDKLGIEYEIYLETGIVGVIEGKRPKKDIAFRADIDGLHSEEGVKHLCGHDGHATILLGLIEYLNDNKEDLNDNIVFIFQPAEEGPGGAKALIDEGVLRKYNVDEIYGLHIYPELPEGYVGTREGYFMAQIGDIDIEIVSKSGHGAMPQNGIDGIVIASNFVNSLQTIVSRNISPIDNAVLTIGRIEGGARRNIIAENIKMEGTMRCFSPEVYEKMKLRVRELARGFELAYNCKVNINIIDDYIAVKNDKDLYQEFVEAVGSDTVVELEPLMISEDFSYYQKEVPGLFFMLGSRNEEKGFVNGLHNINFNFDEKICVNALNVYSALLKYKEAID
>NZ_CP045224.1|WP_009906336.1|466746_466992_+|small,-acid-soluble-spore-protein,-alpha/beta-type
MKEKVQIEKKITNGKNTKILTNDDIMKYEIASELGLMDKVGERGWAGLTAKEAGRIGGMLTSRKKRLKKIVEEQNKKDESI

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Click the colored protein region to show detailed information

Crispr_ID: NZ_CP045224_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045224_3

778952-781073

Unclear

I-A

Consensus_repeat	Method
GTTTTATATTAACTAAGTGGTATGTAAAG	PILER-CR
GTTTTATATTAACTAAGTGGTATGTAAAG	CRISPRCasFinder
GTTTTATATTAACTAAGTGGTATGTAAAG	CRT

32 spacers

cas2,cas1,cas4,cas3,cas5,cas7,cas8b2,cas6,WYL

The CRISPR arrays of NZ_CP045224_3

>merge|NZ_CP045224|3|778952-781073|PILER-CR,CRISPRCasFinder,CRT
GTTTTATATTAACTAAGTGGTATGTAAAGCAATATATTCTAGCAGGAGCAGATTTAGGAGCTTTACAAGTTTTATATTAACTAAGTGGTATGTAAAGATTCTTTATACAGAGAAACACGATACTATTTACAGGTTTTATATTAACTAAGTGGTATGTAAAGATATCTTTGTACTCTTGATTTTCCAGCTTTGATATAGTTTTATATTAACTAAGTGGTATGTAAAGAATTGCATAATATTAGAGAGTTTAATACCATCAAGTGTTTTATATTAACTAAGTGGTATGTAAAGGATGGTAAAATGGGAGATACTTTCTTTGGATTAACAGGTTTTATATTAACTAAGTGGTATGTAAAGTTGCTTATACTTACAACTTTTTCTGCTGTAGCATGTTTTATATTAACTAAGTGGTATGTAAAGAAAACTGTTTCTACTTTTTTAGTCCCAAGTAATTCCGTTTTATATTAACTAAGTGGTATGTAAAGCGCATTTTTGCTTTTATATTGCTTCTTCTATCTTCTAGTTTTATATTAACTAAGTGGTATGTAAAGTCTAAAATATCCTCACAACTCCTGTAATTGTATTTTCTGTTTTATATTAACTAAGTGGTATGTAAAGTGGTTTACTAAGAAAATAACGGATTTTTAAGAGAAAAGTTTTATATTAACTAAGTGGTATGTAAAGTTTGATGAAAAAGAAGAATATAAGAGGGATGTGGCAAGTTTTATATTAACTAAGTGGTATGTAAAGTAACTCCAAACTCCGTAAGTCTTGCCATTTCTCCAAGTTTTATATTAACTAAGTGGTATGTAAAGGAGTATCAAGAGACCAGGGAAAGGCAGGTAAAGCAGGTTTTATATTAACTAAGTGGTATGTAAAGAATGGTAAAATGAAGGCATAATAAATTTCAATATAGGTTTTATATTAACTAAGTGGTATGTAAAGAGAGACAGTTTAAAACTAAATCAGAAGAAAAGTCTTATAGTTTTATATTAACTAAGTGGTATGTAAAGTTTAAAGCACCCTTAAAATCTGGTTGGGCATGTTCTCGTTTTATATTAACTAAGTGGTATGTAAAGTTGGTAGACAACCTGGTACTTGGCTTAAGATTGATAAGTTTTATATTAACTAAGTGGTATGTAAAGCATGTGATAGAGATAATATACAATATGATAGAGAAAGTTTTATATTAACTAAGTGGTATGTAAAGGCATAAAATACCTTCAAAAATAGCTTCTACTGACAGTTTTATATTAACTAAGTGGTATGTAAAGCGAAATAATGTTTTGTTTTCGATGGGTATATATACGGGTTTTATATTAACTAAGTGGTATGTAAAGTAGCTTTTGCGACTGGAAGATACGCAGATAATTTAGTTTTATATTAACTAAGTGGTATGTAAAGATTGTAAGCTCTTTAATTTCTAAATTAGCTCCGATTGTTTTATATTAACTAAGTGGTATGTAAAGTTAAGTAGAGCAATGTATCATGGTTATGTGAAAAGTGTTTTATATTAACTAAGTGGTATGTAAAGCTAGTAAATTTTGCTAAAAGGCACTATTATTGTAGTGTTTTATATTAACTAAGTGGTATGTAAAGCAGTTGACACAATGAGTAAAAGCGAAGCAGAGCAAGATTTTATATTAACTAAGTGGTATGTAAAGTTATGTTATAGGAGCAGGTTGCAAGAAGTATAAGCAAGTTTTATATTAACTAAGTGGTATGTAAAGCATAGATTTTGGAGATTTAAGGGAAGGCAATATGTGTGTTTTATATTAACTAAGTGGTATGTAAAGGGGTTTGCATCTTTATTAGATAATTTTATTAATAGAGTTTTATATTAACTAAGTGGTATGTAAAGTAAATATAGAATAAAGCATTTTAGTTTACAATGCAAGTTTTATATTAACTAAGTGGTATGTAAAGACCTAAAAAATCAATGCAGCTTATCTTATATGCAATGGTTTTATATTAACTAAGTGGTATGTAAAGATTAAGGAATAGTAATTACAGTGGACTGGAGTTAGTGTTTTATATTAACTAAGTGGTATGTAAAGACGTTTCGCAAGGGATTTTTTAAAGCGAATGGATAAGTTTTATATTAACTAAATCATATCTAAAT

>NZ_CP045224|3|1|778952-781008|PILER-CR
GTTTTATATTAACTAAGTGGTATGTAAAG	CAATATATTCTAGCAGGAGCAGATTTAGGAGCTTTACAA
GTTTTATATTAACTAAGTGGTATGTAAAG	ATTCTTTATACAGAGAAACACGATACTATTTACAG
GTTTTATATTAACTAAGTGGTATGTAAAG	ATATCTTTGTACTCTTGATTTTCCAGCTTTGATATA
GTTTTATATTAACTAAGTGGTATGTAAAG	AATTGCATAATATTAGAGAGTTTAATACCATCAAGT
GTTTTATATTAACTAAGTGGTATGTAAAG	GATGGTAAAATGGGAGATACTTTCTTTGGATTAACAG
GTTTTATATTAACTAAGTGGTATGTAAAG	TTGCTTATACTTACAACTTTTTCTGCTGTAGCAT
GTTTTATATTAACTAAGTGGTATGTAAAG	AAAACTGTTTCTACTTTTTTAGTCCCAAGTAATTCC
GTTTTATATTAACTAAGTGGTATGTAAAG	CGCATTTTTGCTTTTATATTGCTTCTTCTATCTTCTA
GTTTTATATTAACTAAGTGGTATGTAAAG	TCTAAAATATCCTCACAACTCCTGTAATTGTATTTTCT
GTTTTATATTAACTAAGTGGTATGTAAAG	TGGTTTACTAAGAAAATAACGGATTTTTAAGAGAAAA
GTTTTATATTAACTAAGTGGTATGTAAAG	TTTGATGAAAAAGAAGAATATAAGAGGGATGTGGCAA
GTTTTATATTAACTAAGTGGTATGTAAAG	TAACTCCAAACTCCGTAAGTCTTGCCATTTCTCCAA
GTTTTATATTAACTAAGTGGTATGTAAAG	GAGTATCAAGAGACCAGGGAAAGGCAGGTAAAGCAG
GTTTTATATTAACTAAGTGGTATGTAAAG	AATGGTAAAATGAAGGCATAATAAATTTCAATATAG
GTTTTATATTAACTAAGTGGTATGTAAAG	AGAGACAGTTTAAAACTAAATCAGAAGAAAAGTCTTATA
GTTTTATATTAACTAAGTGGTATGTAAAG	TTTAAAGCACCCTTAAAATCTGGTTGGGCATGTTCTC
GTTTTATATTAACTAAGTGGTATGTAAAG	TTGGTAGACAACCTGGTACTTGGCTTAAGATTGATAA
GTTTTATATTAACTAAGTGGTATGTAAAG	CATGTGATAGAGATAATATACAATATGATAGAGAAA
GTTTTATATTAACTAAGTGGTATGTAAAG	GCATAAAATACCTTCAAAAATAGCTTCTACTGACA
GTTTTATATTAACTAAGTGGTATGTAAAG	CGAAATAATGTTTTGTTTTCGATGGGTATATATACGG
GTTTTATATTAACTAAGTGGTATGTAAAG	TAGCTTTTGCGACTGGAAGATACGCAGATAATTTA
GTTTTATATTAACTAAGTGGTATGTAAAG	ATTGTAAGCTCTTTAATTTCTAAATTAGCTCCGATT
GTTTTATATTAACTAAGTGGTATGTAAAG	TTAAGTAGAGCAATGTATCATGGTTATGTGAAAAGT
GTTTTATATTAACTAAGTGGTATGTAAAG	CTAGTAAATTTTGCTAAAAGGCACTATTATTGTAGT
GTTTTATATTAACTAAGTGGTATGTAAAG	CAGTTGACACAATGAGTAAAAGCGAAGCAGAGCAAG
ATTTTATATTAACTAAGTGGTATGTAAAG	TTATGTTATAGGAGCAGGTTGCAAGAAGTATAAGCAA
GTTTTATATTAACTAAGTGGTATGTAAAG	CATAGATTTTGGAGATTTAAGGGAAGGCAATATGTGT
GTTTTATATTAACTAAGTGGTATGTAAAG	GGGTTTGCATCTTTATTAGATAATTTTATTAATAGA
GTTTTATATTAACTAAGTGGTATGTAAAG	TAAATATAGAATAAAGCATTTTAGTTTACAATGCAA
GTTTTATATTAACTAAGTGGTATGTAAAG	ACCTAAAAAATCAATGCAGCTTATCTTATATGCAATG
GTTTTATATTAACTAAGTGGTATGTAAAG	ATTAAGGAATAGTAATTACAGTGGACTGGAGTTAGT
GTTTTATATTAACTAAGTGGTATGTAAAG

>NZ_CP045224|3|1|778952-781073|CRISPRCasFinder
GTTTTATATTAACTAAGTGGTATGTAAAG	CAATATATTCTAGCAGGAGCAGATTTAGGAGCTTTACAA
GTTTTATATTAACTAAGTGGTATGTAAAG	ATTCTTTATACAGAGAAACACGATACTATTTACAG
GTTTTATATTAACTAAGTGGTATGTAAAG	ATATCTTTGTACTCTTGATTTTCCAGCTTTGATATA
GTTTTATATTAACTAAGTGGTATGTAAAG	AATTGCATAATATTAGAGAGTTTAATACCATCAAGT
GTTTTATATTAACTAAGTGGTATGTAAAG	GATGGTAAAATGGGAGATACTTTCTTTGGATTAACAG
GTTTTATATTAACTAAGTGGTATGTAAAG	TTGCTTATACTTACAACTTTTTCTGCTGTAGCAT
GTTTTATATTAACTAAGTGGTATGTAAAG	AAAACTGTTTCTACTTTTTTAGTCCCAAGTAATTCC
GTTTTATATTAACTAAGTGGTATGTAAAG	CGCATTTTTGCTTTTATATTGCTTCTTCTATCTTCTA
GTTTTATATTAACTAAGTGGTATGTAAAG	TCTAAAATATCCTCACAACTCCTGTAATTGTATTTTCT
GTTTTATATTAACTAAGTGGTATGTAAAG	TGGTTTACTAAGAAAATAACGGATTTTTAAGAGAAAA
GTTTTATATTAACTAAGTGGTATGTAAAG	TTTGATGAAAAAGAAGAATATAAGAGGGATGTGGCAA
GTTTTATATTAACTAAGTGGTATGTAAAG	TAACTCCAAACTCCGTAAGTCTTGCCATTTCTCCAA
GTTTTATATTAACTAAGTGGTATGTAAAG	GAGTATCAAGAGACCAGGGAAAGGCAGGTAAAGCAG
GTTTTATATTAACTAAGTGGTATGTAAAG	AATGGTAAAATGAAGGCATAATAAATTTCAATATAG
GTTTTATATTAACTAAGTGGTATGTAAAG	AGAGACAGTTTAAAACTAAATCAGAAGAAAAGTCTTATA
GTTTTATATTAACTAAGTGGTATGTAAAG	TTTAAAGCACCCTTAAAATCTGGTTGGGCATGTTCTC
GTTTTATATTAACTAAGTGGTATGTAAAG	TTGGTAGACAACCTGGTACTTGGCTTAAGATTGATAA
GTTTTATATTAACTAAGTGGTATGTAAAG	CATGTGATAGAGATAATATACAATATGATAGAGAAA
GTTTTATATTAACTAAGTGGTATGTAAAG	GCATAAAATACCTTCAAAAATAGCTTCTACTGACA
GTTTTATATTAACTAAGTGGTATGTAAAG	CGAAATAATGTTTTGTTTTCGATGGGTATATATACGG
GTTTTATATTAACTAAGTGGTATGTAAAG	TAGCTTTTGCGACTGGAAGATACGCAGATAATTTA
GTTTTATATTAACTAAGTGGTATGTAAAG	ATTGTAAGCTCTTTAATTTCTAAATTAGCTCCGATT
GTTTTATATTAACTAAGTGGTATGTAAAG	TTAAGTAGAGCAATGTATCATGGTTATGTGAAAAGT
GTTTTATATTAACTAAGTGGTATGTAAAG	CTAGTAAATTTTGCTAAAAGGCACTATTATTGTAGT
GTTTTATATTAACTAAGTGGTATGTAAAG	CAGTTGACACAATGAGTAAAAGCGAAGCAGAGCAAG
ATTTTATATTAACTAAGTGGTATGTAAAG	TTATGTTATAGGAGCAGGTTGCAAGAAGTATAAGCAA
GTTTTATATTAACTAAGTGGTATGTAAAG	CATAGATTTTGGAGATTTAAGGGAAGGCAATATGTGT
GTTTTATATTAACTAAGTGGTATGTAAAG	GGGTTTGCATCTTTATTAGATAATTTTATTAATAGA
GTTTTATATTAACTAAGTGGTATGTAAAG	TAAATATAGAATAAAGCATTTTAGTTTACAATGCAA
GTTTTATATTAACTAAGTGGTATGTAAAG	ACCTAAAAAATCAATGCAGCTTATCTTATATGCAATG
GTTTTATATTAACTAAGTGGTATGTAAAG	ATTAAGGAATAGTAATTACAGTGGACTGGAGTTAGT
GTTTTATATTAACTAAGTGGTATGTAAAG	ACGTTTCGCAAGGGATTTTTTAAAGCGAATGGATAA
GTTTTATATTAACTAAATCATATCTAAAT

>NZ_CP045224|3|3|778952-781073|CRT
GTTTTATATTAACTAAGTGGTATGTAAAG	CAATATATTCTAGCAGGAGCAGATTTAGGAGCTTTACAA
GTTTTATATTAACTAAGTGGTATGTAAAG	ATTCTTTATACAGAGAAACACGATACTATTTACAG
GTTTTATATTAACTAAGTGGTATGTAAAG	ATATCTTTGTACTCTTGATTTTCCAGCTTTGATATA
GTTTTATATTAACTAAGTGGTATGTAAAG	AATTGCATAATATTAGAGAGTTTAATACCATCAAGT
GTTTTATATTAACTAAGTGGTATGTAAAG	GATGGTAAAATGGGAGATACTTTCTTTGGATTAACAG
GTTTTATATTAACTAAGTGGTATGTAAAG	TTGCTTATACTTACAACTTTTTCTGCTGTAGCAT
GTTTTATATTAACTAAGTGGTATGTAAAG	AAAACTGTTTCTACTTTTTTAGTCCCAAGTAATTCC
GTTTTATATTAACTAAGTGGTATGTAAAG	CGCATTTTTGCTTTTATATTGCTTCTTCTATCTTCTA
GTTTTATATTAACTAAGTGGTATGTAAAG	TCTAAAATATCCTCACAACTCCTGTAATTGTATTTTCT
GTTTTATATTAACTAAGTGGTATGTAAAG	TGGTTTACTAAGAAAATAACGGATTTTTAAGAGAAAA
GTTTTATATTAACTAAGTGGTATGTAAAG	TTTGATGAAAAAGAAGAATATAAGAGGGATGTGGCAA
GTTTTATATTAACTAAGTGGTATGTAAAG	TAACTCCAAACTCCGTAAGTCTTGCCATTTCTCCAA
GTTTTATATTAACTAAGTGGTATGTAAAG	GAGTATCAAGAGACCAGGGAAAGGCAGGTAAAGCAG
GTTTTATATTAACTAAGTGGTATGTAAAG	AATGGTAAAATGAAGGCATAATAAATTTCAATATAG
GTTTTATATTAACTAAGTGGTATGTAAAG	AGAGACAGTTTAAAACTAAATCAGAAGAAAAGTCTTATA
GTTTTATATTAACTAAGTGGTATGTAAAG	TTTAAAGCACCCTTAAAATCTGGTTGGGCATGTTCTC
GTTTTATATTAACTAAGTGGTATGTAAAG	TTGGTAGACAACCTGGTACTTGGCTTAAGATTGATAA
GTTTTATATTAACTAAGTGGTATGTAAAG	CATGTGATAGAGATAATATACAATATGATAGAGAAA
GTTTTATATTAACTAAGTGGTATGTAAAG	GCATAAAATACCTTCAAAAATAGCTTCTACTGACA
GTTTTATATTAACTAAGTGGTATGTAAAG	CGAAATAATGTTTTGTTTTCGATGGGTATATATACGG
GTTTTATATTAACTAAGTGGTATGTAAAG	TAGCTTTTGCGACTGGAAGATACGCAGATAATTTA
GTTTTATATTAACTAAGTGGTATGTAAAG	ATTGTAAGCTCTTTAATTTCTAAATTAGCTCCGATT
GTTTTATATTAACTAAGTGGTATGTAAAG	TTAAGTAGAGCAATGTATCATGGTTATGTGAAAAGT
GTTTTATATTAACTAAGTGGTATGTAAAG	CTAGTAAATTTTGCTAAAAGGCACTATTATTGTAGT
GTTTTATATTAACTAAGTGGTATGTAAAG	CAGTTGACACAATGAGTAAAAGCGAAGCAGAGCAAG
ATTTTATATTAACTAAGTGGTATGTAAAG	TTATGTTATAGGAGCAGGTTGCAAGAAGTATAAGCAA
GTTTTATATTAACTAAGTGGTATGTAAAG	CATAGATTTTGGAGATTTAAGGGAAGGCAATATGTGT
GTTTTATATTAACTAAGTGGTATGTAAAG	GGGTTTGCATCTTTATTAGATAATTTTATTAATAGA
GTTTTATATTAACTAAGTGGTATGTAAAG	TAAATATAGAATAAAGCATTTTAGTTTACAATGCAA
GTTTTATATTAACTAAGTGGTATGTAAAG	ACCTAAAAAATCAATGCAGCTTATCTTATATGCAATG
GTTTTATATTAACTAAGTGGTATGTAAAG	ATTAAGGAATAGTAATTACAGTGGACTGGAGTTAGT
GTTTTATATTAACTAAGTGGTATGTAAAG	ACGTTTCGCAAGGGATTTTTTAAAGCGAATGGATAA
GTTTTATATTAACTAAATCATATCTAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045224.1\|WP_003422619.1\|777518_778499_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NZ_CP045224.1\|WP_003422618.1\|776964_777516_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NZ_CP045224.1\|WP_003422610.1\|771148_772999_+\|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1	cas8b2	cd09665_cas8b2_CAS-I-B	gnl\|CDD\|313005
NZ_CP045224.1\|WP_003422616.1\|774628_776950_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|273707
NZ_CP045224.1\|WP_003422608.1\|770405_771143_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	pfam01881_cas6_CAS-I:CAS-III	gnl\|CDD\|187783
NZ_CP045224.1\|WP_003422606.1\|767215_769132_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376899
NZ_CP045224.1\|WP_003422621.1\|778501_778768_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP045224.1\|WP_003422632.1\|782024_782795_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_009906180.1\|783118_783664_+\|biotin-transporter-BioY	unknown	unknown	gnl\|CDD\|376871
NZ_CP045224.1\|WP_003422641.1\|787169_787760_+\|dipicolinate-synthase-subunit-B	unknown	unknown	gnl\|CDD\|181370
NZ_CP045224.1\|WP_003422643.1\|787966_788167_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_003422628.1\|781133_781562_+\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|236715
NZ_CP045224.1\|WP_003422630.1\|781697_781865_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_003422635.1\|783684_784821_+\|thiolase-family-protein	unknown	unknown	gnl\|CDD\|238383
NZ_CP045224.1\|WP_003422607.1\|769410_770328_+\|transcriptional-regulator	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl\|CDD\|379100
NZ_CP045224.1\|WP_003422637.1\|784824_786216_+\|AMP-binding-protein	unknown	unknown	gnl\|CDD\|341288
NZ_CP045224.1\|WP_003422639.1\|786291_787167_+\|dipicolinate-synthase-subunit-DpsA	unknown	unknown	gnl\|CDD\|181371
NZ_CP045224.1\|WP_009906182.1\|773000_773915_+\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	cas7	cd09687_cas7_CAS-I-B	gnl\|CDD\|187818
NZ_CP045224.1\|WP_003422645.1\|788670_791325_+\|bifunctional-acetaldehyde-CoA/alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|237515
NZ_CP045224.1\|WP_003422614.1\|773916_774618_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cd09658_cas5_CAS-I-B	gnl\|CDD\|187789

Protein	Function_ID	Function_description	E-value
NZ_CP045224.1\|WP_003422619.1\|777518_778499_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	2.35554e-174
NZ_CP045224.1\|WP_003422618.1\|776964_777516_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	9.40575e-61
NZ_CP045224.1\|WP_003422610.1\|771148_772999_+\|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1	gnl\|CDD\|313005	pfam09706, Cas_CXXC_CXXC, CRISPR-associated protein (Cas_CXXC_CXXC). CRISPR is a term for Clustered, Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This entry describes a conserved region of about 65 amino acids from an otherwise highly divergent protein found in a minority of CRISPR-associated protein regions. This region features two motifs of CXXC.	1.22053e-18
NZ_CP045224.1\|WP_003422616.1\|774628_776950_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|273707	TIGR01587, CRISPR-associated_endonuclease/helicase_Cas3, CRISPR-associated helicase Cas3. This model represents the highly conserved core region of an alignment of Cas3, a protein found in association with CRISPR repeat elements in a broad range of bacteria and archaea. Cas3 appears to be a helicase, with regions found by pfam00270 (DEAD/DEAH box helicase) and pfam00271 (Helicase conserved C-terminal domain). Some but not all members have an N-terminal HD domain region (pfam01966) that is not included within this model.	1.45683e-57
NZ_CP045224.1\|WP_003422608.1\|770405_771143_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|187783	cd09652, Cas6-I-III, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex; RAMP superfamily protein; Possesses double RRM/ferredoxin fold.	9.11445e-20
NZ_CP045224.1\|WP_003422606.1\|767215_769132_+\|ABC-transporter-permease	gnl\|CDD\|376899	pfam02687, FtsX, FtsX-like permease family. This is a family of predicted permeases and hypothetical transmembrane proteins. Buchnera aphidicola LolC has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both LolC and Streptococcus cristatus TptD have been shown to require ATP. This region contains three transmembrane helices.	2.4854e-09
NZ_CP045224.1\|WP_003422621.1\|778501_778768_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.9342e-28
NZ_CP045224.1\|WP_009906180.1\|783118_783664_+\|biotin-transporter-BioY	gnl\|CDD\|376871	pfam02632, BioY, BioY family. A number of bacterial genes are involved in bioconversion of pimelate into dethiobiotin. BioY is a component of the BioMNY transport system involved in biotin uptake in prokaryotes.	2.69375e-36
NZ_CP045224.1\|WP_003422641.1\|787169_787760_+\|dipicolinate-synthase-subunit-B	gnl\|CDD\|181370	PRK08305, spoVFB, dipicolinate synthase subunit B; Reviewed.	1.97666e-125
NZ_CP045224.1\|WP_003422628.1\|781133_781562_+\|N-acetyltransferase	gnl\|CDD\|236715	PRK10562, PRK10562, putative acetyltransferase; Provisional.	7.042e-46
NZ_CP045224.1\|WP_003422635.1\|783684_784821_+\|thiolase-family-protein	gnl\|CDD\|238383	cd00751, thiolase, Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and eukaryotes (cytosol, microbodies and mitochondria). There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.	6.94409e-113
NZ_CP045224.1\|WP_003422607.1\|769410_770328_+\|transcriptional-regulator	gnl\|CDD\|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	6.43666e-41
NZ_CP045224.1\|WP_003422637.1\|784824_786216_+\|AMP-binding-protein	gnl\|CDD\|341288	cd17633, AFD_YhfT-like, fatty acid-CoA ligase VraA. This family of acyl-CoA ligases includes Bacillus subtilis YhfT, as well as long-chain fatty acid-CoA ligase VraA, all of which are as yet to be characterized. These proteins belong to the adenylate-forming enzymes which catalyze an ATP-dependent two-step reaction to first activate a carboxylate substrate as an adenylate and then transfer the carboxylate to the pantetheine group of either coenzyme A or an acyl-carrier protein. The active site of the domain is located at the interface of a large N-terminal subdomain and a smaller C-terminal subdomain	5.1537e-141
NZ_CP045224.1\|WP_003422639.1\|786291_787167_+\|dipicolinate-synthase-subunit-DpsA	gnl\|CDD\|181371	PRK08306, PRK08306, dipicolinate synthase subunit DpsA.	4.46497e-131
NZ_CP045224.1\|WP_009906182.1\|773000_773915_+\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	gnl\|CDD\|187818	cd09687, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Cst2/DevR family.	3.27427e-54
NZ_CP045224.1\|WP_003422645.1\|788670_791325_+\|bifunctional-acetaldehyde-CoA/alcohol-dehydrogenase	gnl\|CDD\|237515	PRK13805, PRK13805, bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional.	0
NZ_CP045224.1\|WP_003422614.1\|773916_774618_+\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|187789	cd09658, Cas5_I-B, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	1.81963e-63

>NZ_CP045224.1|WP_003422621.1|778501_778768_+|CRISPR-associated-endonuclease-Cas2
MFVIVTYDIVEAKSLNRIRKILRKYLTWTQNSVFEGNITDGKLHKCISEIENIIDNREDSIYIYEIKNPNSIKKKCYGIDKYSDEMFI
>NZ_CP045224.1|WP_003422619.1|777518_778499_+|type-I-B-CRISPR-associated-endonuclease-Cas1
MYKDYYIISNGNIKRKENTIYYYNLEGDKKILPVEQVDDIHIYGEVDLNTKLINYISQYGVMLHFYNYYGYYSGTYYPRKKNVSGFSLVCQSACYLDKNERLYLAKSFVESASYHILRNMRYYKVDESLIDAIKDELNDLNDVKEISELMGKEGRIRKTYYKSFNQILKDDFEFYKREKRPPKDPVNALMSFGNSIMYTNVLSEIYKTQLDPTISFLHEPSTKRFSLSLDIAEIFKPIIIDTIIFSLINNKRINKNDFEYQDKICYLSEKGKKKFLQEFENKMQTTIKHRNLNRKVSYRMFIRLECYKLIKHFINDERYKVLKVWW
>NZ_CP045224.1|WP_003422618.1|776964_777516_+|CRISPR-associated-protein-Cas4
MWLKFTKEGEFVPIDLDLLKVQGVKINYYYVCKRKLWLFSKGITMEQNSSRVLSGKIVHEDSYKRMKNKEMLIDDILKLDIIKDEYVKEVKISSKMKEADEMQLYYYLYYLKNSMGIEKKGTINYVKEKKQEELILTEEKERIIENTLININEINMKLSPPKIEKKPYCTKCAYYEFCFVKEE
>NZ_CP045224.1|WP_003422616.1|774628_776950_+|CRISPR-associated-helicase/endonuclease-Cas3
MLYAKSNPVETLREHTDELLKQMNVLRESYGTNINSLNFLEEEIFWQLLDFVIEFHDIGKAFSPFQELIISRMDTKINEPKIVTHLENNVGHNYLSPAFIDYSYIDKKKNKELRAVLNQVIVYHHERDIFIDKDFKNLIQKILDEDLINKVYELQHEFKVRYPIKTEKLSKVYLQSVEKRIDKNHKYYNLYIMLKGILHRLDHSASAHEVVECNNVMNIGEHTENYLMKEFGSLRETQSFAQSNRNKNIILIASTGMGKTETALIWIDKDKAFFTLPLRVSINALFDRAKNIVGVGESNDTFLGLLHSTAIDYLEESNQENSSEIVDLAKLLSCKLTFSTIDQIFKFPFLYRGYEKVYSTLAYSKVVIDEIQAYSPEIAAVLVKGIEMIHKIGGKFMIMTATMPTIYIDELKKRGVVDSNLANLTCNTEKIRHCVSIVENSIDENLEQIIQSGINKKVLVIVNTVKSAIEKYELIEEIIKSKGIDINVNLLHSMYIQEDRAKLEKYIKEFADSDSNGIWITTQLVEASLDIDFDELHTENSTLDSLFQRFGRCYRSREYEENSPNIFIYTEKATGIGSIYDKDIVEKGLELLKNCMNGKKCFKMKEKHKVQMVKILYSKESLKDTDFEKKFTRALDILDTITPYSLGSNEAQNILRNIEGYTVIPEDIYRKIEKTLIRDYEELGQELTEAYSNDDRQLINEIKSKRKKARREIIKKTVNLPIYKAKQNIVDIQVKGLEDLKILLYKYDIHEDVHTKHIFGKGVIIGKEIDQFI
>NZ_CP045224.1|WP_003422614.1|773916_774618_+|type-I-B-CRISPR-associated-protein-Cas5
MKVLKLDLFQETACYKKPFAMKITETYPLPPYSTINGLIHKILNATEYIPFNISVQGTYESIFNNYQTTYFYKKDSITSMPMNSHMLLNVNLIIHIGGDFDLLKEIYDSLLNYNEHLSLGRKEDLVRITDIRFVEVNKFEIDEDIQLDDYENYKLSECDIRMPIYIPKTSLQDKDIDGISYRLNNYYDNNAVGDKKRVWNKVDSYYVEDGNTISVGDILLDNEGDLLYFNNIN
>NZ_CP045224.1|WP_009906182.1|773000_773915_+|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR
MKRGLTFTVIAQAQSLNYGEGIGNISELKKLSRADGNIYTFASRQCLRYDIVRLAAELFNWNLQVVDKEKGTIQFKDNISIRESEEMDLFGYMKTNKKDEKDKKGGSLTREAAVRLSNAISLEPYRSDMDFLNNKGLADRIGEHPNLANIEQHLSYYTYTVTIDLSKIGKDGEIELDNKEKCRRVVEFLEIIKVLNRNIRGRQENLSPLFVVGGVYEIANPFFLGRIKLKGDKNGFKINKQAIEEVVQGTFLGKYLKEFTYVGMVDGVFINKEEFKGLFEDNFLSVDKFFGQLVKEVKEYYGVN
>NZ_CP045224.1|WP_003422610.1|771148_772999_+|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1
MKLRVYRGDWFFNMGIVGFLNIIKKSNKQAEIFIMEDYIEFDSSFLENFHEYYFNYFMDEYDVSKRIKKSIDYSINFIKSKPDKVKDGIKKIKDTVKQQNDKVKKFDEEKFNLIKEKLDSISKIKSYDEFDSLEILVDETIDIFKIKSINDRLTANLYKYVVQDNYFGQVSFFNVAKAKLDLDGLKQVMFNDYLRQIIYFGELEDLLEENDYDKLKNYLNDRLNSIAKDISEKKVSKSSVNTIEKIMKEINKNFIKKNKSIENIKEYMDSLEICEMCGLYKGILDEYSESNFAPLGVSTNNARNMFWKQEYVSSICDVCKLILFCTPAGATYTRKDYLTNEENEFYLFVNMDTSINELFDRNNSLKAQKSESSNSKDENPFNQLIKSIVEENKLKSEWQLRNILFVEFKASIDSKKCKINYFNIPTYLAKFFVKENKKIQSIYDYKLKSNVLDLILKSKDLKHLINNTLRNIVKSNLESNNKSNISGLSCFNVVQLRTILNNYKRGVYKMDYKKLRKIYESGCEIHDYYIDKNAKNKIEGITYKILNLIKVGNKNDFMQTILRIFSPSEKTPPEEILQIFVEEDLDFESVGYAFVTGLISGKYEGKDKLSNEKEEK
>NZ_CP045224.1|WP_003422608.1|770405_771143_+|CRISPR-associated-endoribonuclease-Cas6
MKMKIEFSTSCIPISYNSLFMSIIKEAIKKSNEDYYKNMYYYKEKNNKKTKNFTFSVYVKKYSIEGDNFIIEDKVILNISTPDLELGFHIYNGLMTSKKCLYKDYELTRIRIDLSREKKVTEERVLFNALSPICVKSKEGKFLEITDDRYIEELNYITNEVVKNYRGSGLKRKLEFENIDLKKVVVKESLREFKKITGKEYQYINGYKGKFILKGDIDDLNIIYNLGLGFRRAQGFGDVDILEWR
>NZ_CP045224.1|WP_003422607.1|769410_770328_+|transcriptional-regulator
MMILIQSRGKMKCKELAEELEVSERQIKSYKMYLEQAGIFINSTPGIYGGYEIDKCNSISLIKLLDSEVSILDMINSQLEYNNDIYKTEFNSIVEKIKAVLNTRVKSDTYMDYFTIQPQRNCDYKFEKNKCNEIIRAYTTKRKLWIEYYSLNSGNSERIVHPYGLFNYKSDTYMVAFCEKRFKFIDFKLCRIKNYKVLEEKYNVDKSFSWDEYSKNSIGIYKGEEINVVIKISHPFSTIIKEKVWVNNQQIIEYDDKSIMFKAKMRGYEEIKSWILSMGAYVEVVDPDSLRNDILSEIEKMKKIY
>NZ_CP045224.1|WP_003422606.1|767215_769132_+|ABC-transporter-permease
MNIKQFAINNISRNIKAYLGYLASITISSSLLFSFVMFTSHPDLDLSQFPDYLKEGLKMSKIIAYLFLFFFVFYSVSVFLKSRYKEFGILYITGISNRQVMKLIFIENMIINIVSSVIGIIIGLIFAKIFLVVMSTFLELSPLKFYIPFNAILSTLIYFMILAVLTSLFTSFIVKENQVLKLLKGTKTPKPEPKTSLMLAILSICLFIIAYYNAVTSTDQYTTYLRLVPVTSLTIAATYLFFSQFSVFFIKKLKLNKRFYRKNTNMLWISNLIYKVKDNARIFFLITITSAVAFTAIGTVYSFWKDVKRQINLIYPNTIYYSTMTLHNDPKKPDSKEKDKERMRFIENNLKKEDIDYTRINGEFKTVFPKKSDFNVRIMKESKYLEITEVIGVKPISFEDNESISLLSSSLPGNKKIKENVTVGNRSLKVAKQVEECVMPAYYKNMYVVKDNFYDSIESKFIVDRFTAFEVEDSSKTIEICREFENKFDNESGMQPYLFFSKELMIETGKLMYSTFIFLAIFIGLIFFVTTSSFLYNKFYMDCQVDKKKYEQLNKLGMTYNEIKKASTIEIGIVFLLPYVVAVIHSIFALTALKNSFDLEVASSAVLVMGSLFLVQIVYFLIVRNNYLKEIKLNLVNY
>NZ_CP045224.1|WP_003422628.1|781133_781562_+|N-acetyltransferase
MIRKLNNKDINKIMEIWEESTIKAHGFISKEYWQNNHNAVKNEYIPISDTFVYDIGDEIKGFISIIDKSFIGALFIKPKYQNLGIGGKLLDYATEKYKSLSLAVYKDNKKAVIFYNKKGFNVVKGQLNEDSGFKEYIMEYSK
>NZ_CP045224.1|WP_003422630.1|781697_781865_+|hypothetical-protein
MVTKEENKIVWCISNLTNLPFKNNKFDIILNVLSPVNYKRFERVLNNYGMARKVC
>NZ_CP045224.1|WP_003422632.1|782024_782795_-|hypothetical-protein
MKVNENNIDEELDELSRKVYLESPDFWISISDKIIDKVFDEMLLFFAVKYNYFNIVCFAIENNYLDLNMPSKNKKYTNIMEHLLDTSKQNEDKKIYNYLLNLNKDNNLDERPILDELNYNTSSDTFEKKDIYLPKYLCPSCNSNIFDTGYKVSNDITYKFSSKEAEPIEISNEVSSIRCCNCDELLEDVTLDKLSNLCKIQNCNNCGSNLTKVGIIAKKKMNFDENTEKFKDVSTSYCCGNCDSEINLSQREHFKI
>NZ_CP045224.1|WP_009906180.1|783118_783664_+|biotin-transporter-BioY
MKNTKVNIQDLTKMSICVALLCISSYIYIPLPFTPAGVTAQTIMINLIALILTPRQAFSTVGVYIMIGLIGIPVFGGGTSGIGKLLSPTGGFYFGFLFAALIISLLKGRNNDIKRYILITIFVGMPIIYFMGTVFMCYFNQMTVEAALFAAVVPFLIGDTIKSVIASFLGTKLNNVLRKNL
>NZ_CP045224.1|WP_003422635.1|783684_784821_+|thiolase-family-protein
MEEVFILGGLRSHIGLKNGIFQFVQPELLGASVLKHLIKKYEIDKIDEIICGNAVGTGGNIARLMTLTAGVSNEVPAFTVDMQCASAMMSIDIAFSKIKSGQCDLIIAGGFESSSLQPMRTYHKNDKRYNINNPNYTVAQFSPDDNSQNSMLEGAERVAELYQIKKAELDFWVKESHKRAKEAREEKIFDDIIFPINNSTCDEGIRDKMSQRLLDRMPSILGKESITNAANSCLINDGASFIILCSKKYLEHAKNKPIAKIVNTCTIGTDANLSPTSAIKAMDKLLEIESLSYLDVSAVEFNEAFAVIDVLFQRKYPELIDRYNIFGGALAYGHPYGASGAIIALHLLKALEKTKGRYGICSIAAAGGLGSALMIERV
>NZ_CP045224.1|WP_003422637.1|784824_786216_+|AMP-binding-protein
MNYYELLRIKSDRHKNKNFLIIDGEKYTYENILSYSEEIGKQIYLGENIPILIYSKNIMFQLISFFAINYSKNIPIICHYNLSKKVLDDILLKNNISIIISDESMDVIDLYDDNNNEVAKKVNLSIFNPKFNIYMYQYKKLINYLDKSICMGALSSGSTSVPKVLYRTYESWAGFFPIQNAIFNISGESILFINGTLSFTGNLNSIMSVLYEGGSIVISSGLNCKSWIRTIKQYNVTNIYLIPIKLQLLVKHLKESVLKVVSIFTGSQLLFEDTARNLKKYMPKSEIILYYGASELNYITYLCYDELIERPLSVGRPFPGIDVYIREEKIFVNTEYAVYNATKPYSVNDIGYFDNDGYLIFEGRSDDIVNIGGFKVSSTKIENEVKKIPQIEDAVVLPYSDTIRGNQIVLFVITIDKITKKDLLIKMKDNLMKNEIPKKIIFLNSFPYTSSEKIDRLALLKML
>NZ_CP045224.1|WP_003422639.1|786291_787167_+|dipicolinate-synthase-subunit-DpsA
MSNQYDITVIGGDLRQVYMVKKLINKGYSVVTYGISNEIINGIVGKSTSLAEALSKSSIILCPIPFTKNQVNIENTDNCLDATIDNLLINLSPNQILFGGNIPTKVCKFCEQHSIQIYDFMKMNDVAILNAVATAEGAISEAIKRSIINIHQSNCLVLGYGRCAQILAKKLYALDANVCVGARNNDARSTASAFGYSSISLNQLDEKLLQFDYIFNTIPDCILTKERLEKVSQEVTIIDIASSPGGVDYSATKEVGINATLCLGLPGKYSPKTSGEILVNAIENIINERRD
>NZ_CP045224.1|WP_003422641.1|787169_787760_+|dipicolinate-synthase-subunit-B
MRLEGLTIGVGFTGSFCTYDKIFIELENLVKEGANVHTIFSDVSQNIDCRFGNSEEFMKKAYELTGNKPIVTIEDAEPFGPKGIADIIIIAPCTGNTAAKLANGITDSPVLMAAKGHLRNDKPLVISISTNDALSFNFKNIGILLNSKNIYFVPFGQDNCKAKPNSMIAHTELIIPTIELALENKQLQPVIKSPHQ
>NZ_CP045224.1|WP_003422643.1|787966_788167_-|hypothetical-protein
MKKLKIISIFSLIISVILTIGGIGIVTYYVNNLFIRGLSVFVLIMSSSFVSTTVRLIFEESKRYKF
>NZ_CP045224.1|WP_003422645.1|788670_791325_+|bifunctional-acetaldehyde-CoA/alcohol-dehydrogenase
MAHKEQVIIENKKENEVMSVGLDTVNNVESLVKKLAKIKEAQKIFATYTQEQVDKIFLAASLAANKQRVPLAIMAQKETGMGIAEDKVIKNHYASEYIYNAYKETKTCGVIEKDEAFGMTKIAEPIGVIAAVVPTTNPTSTAIFKALLALKTRNGIIFSPHPRAKNSTIEAAKVVLEAAVLAGAPEGIIGWIDEPSLELTTTVMKEVDLTLATGGPGMVKSAYSSGKPAIGVGAGNTPAIIDESADIKTAVNSILVSKTFDNGMICASEQSVIVLENIYNEVKKEFKERGAYLLDKDETEKIRNIILVNGGLNSKIVGQTACTIAKLAGFEVPVDTKVLIGEVESVEIEEAFAHEKLSPVLAMYKASDFDDAVRKAEKLVEDGGFGHTSSLYIDDVNQREKLDKFTSAMKTCRILINTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVSENVGVKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVALKELKDVMDKKRAFIVTDTFLYNNGYTKAVTDLLDEMNIKHTTFFEVEPDPTLECAKIGAKAMREFNPDVIISIGGGSAMDAGKIMWTLYEHPDVDFQDLAMRFMDIRKRVYTFPKMGEKANFVAIPTSAGTGSEVTPFAVITDQDTGVKYPLADYELMPNMAIVDSDMMMNMPKSLTSASGIDALTHALEAYVSMLATDYTNGLALQAIKSIFEYLPRAYDNGAKDPEAREKMANASTMAGMAFANAFLGVCHSMAHKLGAFHHVPHGVANALLITEVMKFNSSDAPKKMGAFSQYKYPEALKRYAEVASFLGLKGNSEEEKFQSLLSAIEDLKFKVGIPKTIKEFGVEESKFMDSIDEMVIQAFDDQCTGANPRYPLMNEIKDMYLNSYYGR

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Crispr_ID: NZ_CP045224_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045224_4

886576-886658

Orphan

Consensus_repeat	Method
AATCCACCAGTACCACCATCAGAAGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045224_4

>merge|NZ_CP045224|4|886576-886658|CRISPRCasFinder
AATCCACCAGTACCACCATCAGAAGATATGACAAATCCACCAATACCAGAGGTAGTTAATCCACCAATACCACCATCAGAAGA

>NZ_CP045224|4|2|886576-886658|CRISPRCasFinder
AATCCACCAGTACCACCATCAGAAGA	TATGACAAATCCACCAATACCAGAGGTAGTT
AATCCACCAATACCACCATCAGAAGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045224.1\|WP_003422792.1\|889163_890354_-\|pyridoxal-phosphate-dependent-aminotransferase	unknown	unknown	gnl\|CDD\|180720
NZ_CP045224.1\|WP_003422778.1\|872421_873120_+\|response-regulator	unknown	unknown	gnl\|CDD\|381091
NZ_CP045224.1\|WP_003422790.1\|887247_887910_+\|zinc-metalloprotease-Zmp1	unknown	unknown	gnl\|CDD\|380333
NZ_CP045224.1\|WP_003422788.1\|882471_883650_+\|cation-transporter	unknown	unknown	gnl\|CDD\|223131
NZ_CP045224.1\|WP_003422795.1\|892283_892814_+\|flavodoxin	unknown	unknown	gnl\|CDD\|378898
NZ_CP045224.1\|WP_003422799.1\|897030_897612_+\|dihydrofolate-reductase	unknown	unknown	gnl\|CDD\|223340
NZ_CP045224.1\|WP_003422780.1\|873403_874492_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226458
NZ_CP045224.1\|WP_009906135.1\|897856_899584_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP045224.1\|WP_003422791.1\|888031_888994_-\|EamA-family-transporter	unknown	unknown	gnl\|CDD\|273359
NZ_CP045224.1\|WP_044482736.1\|876005_877508_+\|AbgT-family-transporter	unknown	unknown	gnl\|CDD\|225525
NZ_CP045224.1\|WP_003422787.1\|879006_881781_+\|calcium-translocating-P-type-ATPase,-PMCA-type	unknown	unknown	gnl\|CDD\|223550
NZ_CP045224.1\|WP_003422798.1\|895620_896733_-\|alanine-racemase	unknown	unknown	gnl\|CDD\|143494
NZ_CP045224.1\|WP_003422774.1\|869258_870530_+\|serine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235461
NZ_CP045224.1\|WP_003422794.1\|891107_892202_+\|NADH:flavin-oxidoreductase	unknown	unknown	gnl\|CDD\|239201
NZ_CP045224.1\|WP_003422796.1\|893140_893974_+\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133378
NZ_CP045224.1\|WP_003422786.1\|877579_878836_+\|serine-hydroxymethyltransferase	unknown	unknown	gnl\|CDD\|234571
NZ_CP045224.1\|WP_003422776.1\|870802_872308_+\|histidine-kinase	unknown	unknown	gnl\|CDD\|340432
NZ_CP045224.1\|WP_003422770.1\|866870_868472_+\|amidohydrolase	unknown	unknown	gnl\|CDD\|238625
NZ_CP045224.1\|WP_003422782.1\|874722_875907_+\|amidohydrolase	unknown	unknown	gnl\|CDD\|349882
NZ_CP045224.1\|WP_003422793.1\|890659_891106_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224759

Protein	Function_ID	Function_description	E-value
NZ_CP045224.1\|WP_003422792.1\|889163_890354_-\|pyridoxal-phosphate-dependent-aminotransferase	gnl\|CDD\|180720	PRK06836, PRK06836, pyridoxal phosphate-dependent aminotransferase.	0
NZ_CP045224.1\|WP_003422778.1\|872421_873120_+\|response-regulator	gnl\|CDD\|381091	cd17536, REC_YesN-like, phosphoacceptor receiver (REC) domain of YesN and related helix-turn-helix containing response regulators. This family is composed of uncharacterized response regulators that contain a REC domain and a AraC family helix-turn-helix (HTH) DNA-binding output domain, including Bacillus subtilis uncharacterized transcriptional regulatory protein YesN and Staphylococcus aureus uncharacterized response regulatory protein SAR0214. YesN is a member of the two-component regulatory system YesM/YesN and SAR0214 is a member of the probable two-component regulatory system SAR0215/SAR0214. Also included in this family is the AlgR-like group of LytTR/AlgR family response, which includes Pseudomonas aeruginosa positive alginate biosynthesis regulatory protein AlgR and Bacillus subtilis sensory transduction protein LytT, among others. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	5.38958e-43
NZ_CP045224.1\|WP_003422790.1\|887247_887910_+\|zinc-metalloprotease-Zmp1	gnl\|CDD\|380333	cd20183, M34_PPEP, Pro-Pro endopeptidase (PPEP) and similar proteins; belongs to peptidase family M34. This subfamily includes the enzyme Pro-Pro endopeptidase (PPEP-1, EC 3.4.24.89, also known as Zmp1 (Clostridium difficile-type)), an extracellular metalloprotease showing a unique specificity for hydrolyzing a Pro-Pro bond. It belongs to peptidase family M34 and has the hallmark metalloprotease motif HEXXH, where the two His residues bind a single zinc atom, and the Glu has a catalytic role. PPEP-1 cleaves two C. difficile cell surface proteins (CD2831 and CD3246) involved in adhesion, one of which is encoded by the gene adjacent to the ppep-1 gene. There are multiple PPEP-1 cleavage sites located just above the site of attachment to the peptidoglycan layer. PPEP-1 may play a role in switching from an adhesive to a motile phenotype. Also included in this subfamily is Paenibacillus alvei PPEP-2, a secreted Pro-Pro endopeptidase. The cleavage motif of PPEP-2, PLP PVP, is distinct from that of PPEP-1 (VNP PVP). PPEP-2 cleavage sites in a cell-surface protein, with putative extracellular matrix-binding domains, and encoded by the adjacent gene, suggests a similar role of PPEP-2 in controlling bacterial adhesion.	3.51846e-105
NZ_CP045224.1\|WP_003422788.1\|882471_883650_+\|cation-transporter	gnl\|CDD\|223131	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism].	3.90032e-76
NZ_CP045224.1\|WP_003422795.1\|892283_892814_+\|flavodoxin	gnl\|CDD\|378898	pfam12641, Flavodoxin_3, Flavodoxin domain. This family represents a flavodoxin domain.	2.71623e-67
NZ_CP045224.1\|WP_003422799.1\|897030_897612_+\|dihydrofolate-reductase	gnl\|CDD\|223340	COG0262, FolA, Dihydrofolate reductase [Coenzyme metabolism].	1.02782e-20
NZ_CP045224.1\|WP_003422780.1\|873403_874492_+\|hypothetical-protein	gnl\|CDD\|226458	COG3949, COG3949, Uncharacterized membrane protein [Function unknown].	8.27479e-47
NZ_CP045224.1\|WP_009906135.1\|897856_899584_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.32402e-155
NZ_CP045224.1\|WP_003422791.1\|888031_888994_-\|EamA-family-transporter	gnl\|CDD\|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	2.0282e-15
NZ_CP045224.1\|WP_044482736.1\|876005_877508_+\|AbgT-family-transporter	gnl\|CDD\|225525	COG2978, AbgT, Putative p-aminobenzoyl-glutamate transporter [Coenzyme metabolism].	0
NZ_CP045224.1\|WP_003422787.1\|879006_881781_+\|calcium-translocating-P-type-ATPase,-PMCA-type	gnl\|CDD\|223550	COG0474, MgtA, Cation transport ATPase [Inorganic ion transport and metabolism].	0
NZ_CP045224.1\|WP_003422798.1\|895620_896733_-\|alanine-racemase	gnl\|CDD\|143494	cd06820, PLPDE_III_LS_D-TA_like, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Low Specificity D-Threonine Aldolase-like. This subfamily is composed of uncharacterized bacterial proteins with similarity to low specificity D-threonine aldolase (D-TA), which is a fold type III PLP-dependent enzyme that catalyzes the interconversion between D-threonine/D-allo-threonine and glycine plus acetaldehyde. Both PLP and divalent cations (eg. Mn2+) are required for catalytic activity. Low specificity D-TAs show similarity to bacterial alanine racemase (AR), which contains an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain. AR exists as homodimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. Based on its similarity to AR, it is possible that low specificity D-TAs also form dimers in solution. Experimental data show that the monomeric form of low specificity D-TAs exhibit full catalytic activity.	1.24422e-97
NZ_CP045224.1\|WP_003422774.1\|869258_870530_+\|serine--tRNA-ligase	gnl\|CDD\|235461	PRK05431, PRK05431, seryl-tRNA synthetase; Provisional.	0
NZ_CP045224.1\|WP_003422794.1\|891107_892202_+\|NADH:flavin-oxidoreductase	gnl\|CDD\|239201	cd02803, OYE_like_FMN_family, Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Members of OYE family include trimethylamine dehydrogenase, 2,4-dienoyl-CoA reductase, enoate reductase, pentaerythriol tetranitrate reductase, xenobiotic reductase, and morphinone reductase.	1.47836e-80
NZ_CP045224.1\|WP_003422796.1\|893140_893974_+\|MerR-family-transcriptional-regulator	gnl\|CDD\|133378	cd00592, HTH_MerR-like, Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators. Helix-turn-helix (HTH) MerR-like transcription regulator, N-terminal domain. The MerR family transcription regulators have been shown to mediate responses to stress including exposure to heavy metals, drugs, or oxygen radicals in eubacterial and some archaeal species. They regulate transcription of multidrug/metal ion transporter genes and oxidative stress regulons by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	4.73345e-24
NZ_CP045224.1\|WP_003422786.1\|877579_878836_+\|serine-hydroxymethyltransferase	gnl\|CDD\|234571	PRK00011, glyA, serine hydroxymethyltransferase; Reviewed.	0
NZ_CP045224.1\|WP_003422776.1\|870802_872308_+\|histidine-kinase	gnl\|CDD\|340432	cd16956, HATPase_YehU-like, Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli YehU. This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) including Escherichia coli YehU, a HK of the two-component system (TCS) YehU-YehT which is involved in a nutrient sensing regulatory network. Proteins having this HATPase domain also contain a histidine kinase domain (His-kinase); some have a GAF sensor domain while some have a cupin domain.	3.39542e-46
NZ_CP045224.1\|WP_003422770.1\|866870_868472_+\|amidohydrolase	gnl\|CDD\|238625	cd01300, YtcJ_like, YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling.	5.85783e-158
NZ_CP045224.1\|WP_003422782.1\|874722_875907_+\|amidohydrolase	gnl\|CDD\|349882	cd03886, M20_Acy1, M20 Peptidase Aminoacylase 1 family. Peptidase M20 family, Aminoacylase 1 (ACY1; hippuricase; acylase I; amido acid deacylase; IAA-amino acid hydrolase; dehydropeptidase II; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14) subfamily. ACY1 is the most abundant of the aminoacylases, a class of zinc binding homodimeric enzymes involved in the hydrolysis of N-acetylated proteins. It is encoded by the aminoacylase 1 gene (Acy1) on chromosome 3p21 that comprises 15 exons. N-terminal acetylation of proteins is a widespread and highly conserved process that is involved in the protection and stability of proteins. Several types of aminoacylases can be distinguished on the basis of substrate specificity; substrates include indoleacetic acid (IAA) N-conjugates of amino acids, N-acetyl-L-amino acids and aminobenzoylglutamate. ACY1 breaks down cytosolic aliphatic N-acyl-alpha-amino acids (except L-aspartate), especially N-acetyl-methionine and acetyl-glutamate into L-amino acids and an acyl group. However, ACY1 can also catalyze the reverse reaction, the synthesis of acetylated amino acids. ACY1 may also play a role in xenobiotic bioactivation as well as the inter-organ processing of amino acid-conjugated xenobiotic derivatives (S-substituted-N-acetyl-L-cysteine). ACY1 appears to physically interact with Sphingosine kinase type 1 (SphK1) and may influence its physiological functions; SphK1 and its product sphingosine-1-phosphate have been shown to promote cell growth and inhibit apoptosis of tumor cells. Strong expression of the human gene and its mouse ortholog Acy1 in brain, liver, and kidney, suggest a role of the enzyme in amino acid metabolism of these organs. Defects in ACY1 are the cause of aminoacylase-1 deficiency (ACY1D), resulting in a metabolic disorder manifesting encephalopathy and psychomotor delay.	0
NZ_CP045224.1\|WP_003422793.1\|890659_891106_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|224759	COG1846, MarR, Transcriptional regulators [Transcription].	9.70256e-19

>NZ_CP045224.1|WP_003422788.1|882471_883650_+|cation-transporter
MFSKILVKTFIRDSENVQNRDVRNKYGYVAGVVGILSNLLLFVIKVFIGMLTSSIAIMADAFNNLSDMASSAITMIGFKLASKPADKEHPFGHGRIEYLSALIVAFMVMLVGLQFVKSSIERIVNPVPIKFEVIPLILLIASIMIKIWLSRFNKFMGNKIDSSALKAVSLDALGDVFTSSCVVISFIVARFTNFPIDGYVGIVVSLVILYAGFSLVKDTINPLLGEAPDEDMVNSIIELLLSYKHIIGTHDLIIHNYGVGRCIASIHAEIPSNIDIMEIHEIIDTAEREISEKLDIYLVIHMDPVCLEDKEVMSAKKELEEILKKNSLVKSMHDFRIVGKGSKKNLIFDIVVNPSEFSKNMSEDDLKEDITKLVKEINPEYDCVIVVDKDFI
>NZ_CP045224.1|WP_003422787.1|879006_881781_+|calcium-translocating-P-type-ATPase,-PMCA-type
MRYYNKPTKEVLKYLKTNPEIGLDDNEVEERKLRYGLNEFTIKEGRTFWDELGESLTEPMILILIGAAVISSFVGELHDALGILGAIFIGISIGIITEGKSKKAAQALSKLTENIEVKVLRNGKIIKISKNDLVPGDIVYIETGDMIPADGRLIQSINLKLREDMLTGESDDVAKNADAVLDMEVVYSKTEIIEQDAIPAKQVNMVFGGTLVAYGRGIMVVTHTGDKTEMGKIAQNLSNEDQQTPLQIKLGKLGAKIAGISGVIATLLCMFMIIQMQRKGMLILDTSSVLSFLQSLEPAKNAYMVCIALIVATVPEGLPTMINITLAITMQKMAKINALVTKKEACETIGSVSVICSDKTGTLTQNKMMVEVAYVDGKYISGGEYQSNSYFEQNCIVNSTADIEKEDNSFKYIGSATECALLLYHNDKNYNEMRKQTYLISQIPFSSEEKKMSTLIRQEDSDILLSKGAPEVLLKKCSYVQQGKNIVPITSKIEKSILDEIKKLQIKSMRTLGFAYKKMSNSKTEVAITSEGELNLIGSSRSYMKEDNLVFSGFVGIIDPLREGVKESIDKAFNAGVDVKMLTGDNINTATAIGNELGLLNDGKKAVEATYIDVLTDKELREEIKGISIVARSKPDTKMRIVSALQKSGEVVAVTGDGINDAPALSQADVGIAMGISGTEVSKNAADIILTDDSFSTIVEGIKWGRGIYENFQRFIQFQLTVNIVAFIIAIISQLTGKDMPFTTIQLLWVNIIMDGPPALALGLEPVRDYVLKRKPINRHSGIIARSMFVNIIINAILIITIVFAQSAFNILGATSEEQGTVIFSLFAFSALFNALNCREFGLNSTIPNFFKNKLALQIIVVTGIIQIIFTQVFQSFFNSVSLDFDMWIKIILFASTILLSNEFVKLILRMMKNSRTMNCNSKN
>NZ_CP045224.1|WP_003422786.1|877579_878836_+|serine-hydroxymethyltransferase
MLKTTKISDPELYKIVANELVRQEHNIEMIASESTAPTEVLELSGCVFTNKTEEGYPGARFQAGSEEADKLETLAIKRAKEVFGAEHVNVQPYSGSTANYCVYSSILKPNDTVLSMRLDQGGHLTHGSTVNFLHDIYKYEFYGVDPNTGRIDYDALEAKAKECKPKLIIAGASSYPRLIDYERISKVAKEVGAYFMVDMAHVAGLVAAKVIPSPVPYADFVSSSTTKTFCGPRSGIILCKAEHAKKLDKGVFPGTLGSIHLNTVAAKAFSLLYLGTDKFKKIMEQVVVNAQTLASELISHGFSIVSGGTDNHIVMVDLRSKNLTGKQFEKALEYVGITVNKNVIPDDPQSPFVTSGVRIGLTSISQRGLKEKEVIQIAGIMNKVAENIDNKEVLDECKAEAQELISKFPLYPEGYFED
>NZ_CP045224.1|WP_044482736.1|876005_877508_+|AbgT-family-transporter
MRALNVIERAGNKLPDPVTIFLLLCIIVVILSAIISNLGVEEIHPSTKEVVKVVNLLEKEQIQSYLGSIVTNFQSFAPLGLVLVTMLGAGVAEKSGFMEVLMKKGISKVPQKLVTVAIVFAGMLSHTAADVGFIILPPLAALVFLGIGRHPLVGMFAAFAGVAGGFAANVMLSTTDVLLAGFTIPAAQMMDSSYQGNPAMNLYFAFVSAIILTFAGAFVTEKFIAPRFSKYSDAVNDKDMEELSELENKGIKYALLSLLAIVVIIVALCIGENAFMKDPETGSILSSNAPLMKGIVPIITIIFLTPGLVYGRVSNKIKNDKELVSMMGSSMSDMGGYIVLAFIASQFINLFNLSNLGTILSITGAKVLAESGIPSYGLIIGFILLSGFINLFVGSASAKWAILAPIFVPMFMLLDFNPALTQIAYRIGDASTNPISPLFPYFPVILAFARRYDKDIGIGTVISNMIPYSVVFTLIEVIILLLFMSIGIPLGPGGGISYVL
>NZ_CP045224.1|WP_003422782.1|874722_875907_+|amidohydrolase
MHELISISEKYKEDILDFFTDIHMHPELSFKEFRTTKVIKDLLVSLDIEILDLGMETGVVGLLKGKYDGPTVALRGDIDALPICEEVDIEYKSRYDGIMHACGHDIHTSCLVGCAYVLSHIRDSLHGNVKFIFQPAEEVNKGAKMLVERGVMENPKVDAIFGLHNHPDIPCGKIGVKLGGLMAAVDTIKIEVNGFGGHGGIPNRTIDPIVASSAIIMGIQTIVSRNISPLESAVISIGTINGGTANNVISEKVDMTGTCRSFSNEVRKKISENLEKIVCEIARGYQATAKLDYLFDLPAVINSKEMYTIACKSVCDLYSEDAIVDPVPSTGGEDFSIFMEKAPGFFYWLGVGNKEQDCMYQWHNPKFKADKNSILVGTNVLCQSVINYMDKLKK
>NZ_CP045224.1|WP_003422780.1|873403_874492_+|hypothetical-protein
MSDKVNIKNIICIAGAYLATAIGSGFATGQEILQFFASQGYMGLVGALISMVLFSFLGAEVITRGRELKLKEPTRIYTFYCGKILGKFYEWFSPIFLFGILIVMISGAGSTLTEYYGINPYLGRVLMAVATLITVSMGLEKLVSILGRIGPVIAVFTIAVGLISLFKHFDGLSMVGEAMKNIEVTKASESPIISGVIYNTLNIIVMIVFLTGMGASIESKKDAFWGGLLGGIVFMTAGIVMYLAMISDIGNLYMKEIPSLYLADNIAPIVGVCFSVALILGIYTTAVPLLWSVTNRIVEDEHPKFKLVTTVIAILACIGGFLPFGKLVNILYPYTGYMGLLILVCMVYKAITCREKSTQGQE
>NZ_CP045224.1|WP_003422778.1|872421_873120_+|response-regulator
MRRALIIDDEEAVLKIITHFIEMKDMPIKIVGKATSGDEAVDKITGLEPDIVFIDIQMPIYNGLEVIEKTSHLSKKINFVVITAFDYFEYAQKALRLNVKDILLKPLDMKEFTKSVEKIIGYQYTNNDLLNEILEYINLNYSNDLKLNDCARLFLTNPSNISRIFKSNLNTTFISYLNHIRIEKSIELLENTTKSINEIAEIVGYNSLNNFYKNFKIKKGMTPKVYKLNTKN
>NZ_CP045224.1|WP_003422776.1|870802_872308_+|histidine-kinase
MKIQNTEWGYIEWKHTYDENNPKQAMNIYIAVTMPGKKHFNHVHYGQEQMIYILEGEGLYIINGVWKPFYQGMIFYIESGSTHETINTGDREIKELVVSNIVNNFETSEILEFNKNNKIENTPVNYSENTLNLYAAVESIRGQFIDPFKIPLIIYDDYWNIVLKNPYFPLFCFEKCNPMKFPQNCDCMNQKSANQFTCKYGITIYNISIIYKNNSIGVIRGGYILMSDSSLGVGHRNLYDIPEGAARTMKRLLNQIAKNIINFCSFNDIRKDLQEKEKTIARTYHYGEQLEMNLKVAQDMVTNLRINHHFLFNTLNSMVSIALDDGSYDLYSAIIDLSRMFRYTMRSDLRFVELESEILYIENYLNLQKLRYGDALKVKYLIPKKLYNLSVPFNFIQPIVENAFTHGSRDIDTEKRIEIIARLDSQYAIIEIHNNGTILDKNNIDKIKAGIRINNGHGLSLIYTKFTSAYGNNFDMDIKSSDNEGTYIMIKIPSENYKEYV
>NZ_CP045224.1|WP_003422774.1|869258_870530_+|serine--tRNA-ligase
MLDIKRIRENLDCIKKAMERRGEKAFNLDEVVKLDDERRKILQEVEVMKNKLNTASKNIPNLIKEGKDVENEKIKLKDLSDKIKVIDQNLKEVEDKMEYLLMRIPNVPHPGVPQGETDDDNVEVRSWGETTKFDFESKAHWEIGTELGILDFETASKITGSRFTLYKGLGARLERALLNFYLDTNTKVNGYTEVIPPFMANRNSFLGTGQLPKFEEDMFKIEGLDYFMIPTSEVPLTNIHANEILKFEQLPINYTAYTPCFRSEAGSAGRDTRGLVRQHQFNKVEMVKIVAPEESYNELEKLTNNAETMLQLLNLPYRVVKICTGDLGFTASFKYDVEVWMPSYNRYVEISSCSNCEDFQARRAGIRFKRDKDSKAEYAHTLNGSGLAIGRSVAAILENYQQEDGSVIVPEVLRPYMGVSVIK
>NZ_CP045224.1|WP_003422770.1|866870_868472_+|amidohydrolase
MKEKIYYNGNIITMEDSICGDAILIKDKIIKKIGTKEEVFALKNKDTEIIDLQGKTLMPSFIDSHSHLIAFATTLKLVPLEDATSFKDIVKKIQDFKESNNIKKGDWIIGFSYDNNFLEENKHPDKNVLDSASSENPILISHASGHMGVANTLGLKQLGVTNETYDPEGGHIGRVEGSEEPNGYLEENAFFNVSSKIKPPSSNEIFNSIEKAQDIYLSYGITTAQEGLMEENQFNLLKAMANQNKLKIDVVGYVNLKKSKPVADNNREFIKKYINRFKIGGYKIFLDGSPQGKTAWLSKPYENSDDGYCGYPIYKDEEVEKFIDISLKEKMQLLTHCNGDAAAEQLIDVFEKVLTLKEQSSNNMRPVMIHAQTVREDQIDDMKRINMIPSYFVAHTYYWGDIHIKNLGEDRAFKISPLKTTIEKGLIYTLHQDTPVIAPNMLETVWCAVNRITKKGVQIGENEKISPLDALKGVTINAAYQYFEEDKKGSIKEGKLANLIILDENPLTIDPMKIKDIKVLQTIREGEVLYSLK
>NZ_CP045224.1|WP_003422790.1|887247_887910_+|zinc-metalloprotease-Zmp1
MRPSKKLLIAIISIFLISSVPVSAHAESTTIQQNKDILSQIVVFPTGNYDKNEANAMVNRLANIDGKYLNVLNQNNLKIKLLSGKLTDEKEYAYLKGVVPKGWEGTGKTWDDVPGLGGSTVALRIGFSNKGKGHDAINLELHETAHAIDHIVLNDISKSAQFKQIFAKEGRSLGNVNYLGVYPEEFFAEAFAYYYLNQDTNSKLKSACPQTYSFLQNLAK
>NZ_CP045224.1|WP_003422791.1|888031_888994_-|EamA-family-transporter
MKKGYVYIILTTLFFSSMEISLKTVTNDFNPLQITLSRFFVGGLVLLPFAVKRLRALNLSITKSDLKYFAFLGFMCVVVSMSLYQLAVLNTKASVVAVLFSCNPVFVMLLAYLILKEKIYRHNVISLILEVLGIIVIINPLHTKLTLSGIFLTLSSAIIFSMYTVFGKRKTLKFGGIVVTCFSFIFGSLEMLILVLLTKINFIADILSKNKLNVFANIPIFSGYTLHNMPIMIYVFVFVTGVGYALYFMAMEATSTSLTSLVFFFKPVISPILALLILKEIIPINMIIGILLIVIGSIISIIPTIITQMHNKHVEALYKE
>NZ_CP045224.1|WP_003422792.1|889163_890354_-|pyridoxal-phosphate-dependent-aminotransferase
MISNKMQTLVANSSVIRAMFEEGKKLSDIYGEENVFDFSIGNPSVEPPETIKAVINDILNEESPNLVHGYMNNSGYEDVRDAIAEHINKKDGLNLTKENLIMTCGAAGGLNIILKTLLNPGDEVIAFAPYFGEYKNYTENYDGKLIEVPTNIETFEPDLDALENAITPKTRALIINTPNNPTGVIYSEELLKNLGELLDSKQKEFNTNIYLISDEPYREIIYDGAKVPCVLKYYRNSFIGYSYSKSLSLPGERIGYIVANGQMDDFDDVMSSLNVANRILGFVNAPSLFQRVIARSLDAEVDVNIYKKNFDLLYNSLIDMGYSCVKPSGTFYLFPKAPIEDDKKFCNDAKQFNLLLVPGSSFGCPGHFRVSYCVSYDKVKSSLPAFEKLAKLYNLK
>NZ_CP045224.1|WP_003422793.1|890659_891106_+|MarR-family-transcriptional-regulator
MDFKNLQYESLSYIICNLQKNFKLYCEKCLKPYKLTNGLYFYLIYINKNRNCSLNDVSTEFEVDKAHTTRTISRLEQDGYIEKIQNPNDSRAFQLRVTDKGEEVLGDIKNIFSKWDNRIKKEFSDEEYKELVKKLHVVKDIKTAMEEE
>NZ_CP045224.1|WP_003422794.1|891107_892202_+|NADH:flavin-oxidoreductase
MYCNLLKPIKIGNLELKNRVSFAPTSMGLKLEEKIKKFCDIAKSGVALITLGDVSVRPSFHNMAMSLTDEDGVMKYKKIVDEIHNSGAKVSAQIFCSDYDVNLIKDTMKMGITSHVEIKKIMNDGVKDYITNMPKEEIKNIINLFKVTALNAKKAGFDMIQIHGDRLIGSFSSSIFNNRNDEYGGTCENRSRFASEIISSIRNEVKDIPIDYKFAIRQENPHYGNAGVLFSEVEYFVKKFESLGVNSFHVTLANHSKLEDTIPINNHPYFKDEGCFLYLADEVKKHTNLPVCGVGKLSSPDFIESIISNNRVDMISMSRQLLADSNWLQKVKDGRVDEIKKCCYCNKKCADALQTHSQFGCILD
>NZ_CP045224.1|WP_003422795.1|892283_892814_+|flavodoxin
MKSLILYSSLTGNTKKIACSIYEAIQGKKEIKNISELVDDSIDYENYDIVFLGYWVDKGICDKNSKQVLENIHNKKIALFGTMGASTKGSYGASIIEKIESIIPKDNEILGSFICQGKIAEGLKVKYKEMLKLSPDNEHIRQQLNNHEESQSHPDEQEIYEANVFAKNMMIKASTM
>NZ_CP045224.1|WP_003422796.1|893140_893974_+|MerR-family-transcriptional-regulator
MTIKEVEEKTGLTRSNIRFYENENLIKPLRNERNGYREYSDENIEDIKKIAYLRTLGITIDDIRNIILQKVSLVEVVEKQEKVLETKISDLENAKTMCNKMLESDELSYLNLKVEQYITELPEYWNKNKPVFKLDSVSFLYIWGRKITWGIITIACLLIAIIVFPKLPHQIPIQWNNGVANYVDKKFIYAYPAICVVFRILLRPFIWRWLQIHAFYSDTIADYLTNFMCFVALSIEIFSILFIYNIARHVTIIIFIDIFVFIALLIIGVYKLFKKYN
>NZ_CP045224.1|WP_003422798.1|895620_896733_-|alanine-racemase
MKISEVSTPNFLLDLDQLEKNIDKIQQICTNNNKQLWPMLKTHKSTYIARLQKNAGASGFLVGTLDEGEALIKAGFEDIMLAYPYMGEVNINRIVTMASKINLICATDNIECAKAYSEAFSKSKLECKLLIIVDCGLHRFGVEPEKVVELATEISKLENIKIVGISSHPGQVYGCSSPEGVPDVCVQEDSSMEKAYKALTDNGFNIEIVASGSTPTVEAEAVSKTITAVRPGNYVYYDAIQIGLGCATEDMCALTVVCTVISKNSSGYYLIDCGSKCLGLDKGAHGNSSIVGYGRVCGHPELTIDSLSEEVGKIKVNGETDIKIGDRIRIIPNHSCSTANLTSNLLGFRGDTIERVIEVDIRENSKQIIL
>NZ_CP045224.1|WP_003422799.1|897030_897612_+|dihydrofolate-reductase
MLEVVNMRGVVNMRKVILYIATSLDGYIAEEDGSVSFLDEISSVFKNEQEDDYNTFYDTIDTIIMGNSTYVQIANELSPNEWYYKGKECYVYSNIINEITENVKYTNLEPKKLIEQIGREKDKKDIWIVGGGDIVKLFMKDNLIDDYYIYILPIILGRGISLFKSGIDKTNLNFKKASNIGELVKLEYSKKQK
>NZ_CP045224.1|WP_009906135.1|897856_899584_+|ABC-transporter-ATP-binding-protein
MKLILSYLKNYKLLIVLNILAIFSFALVELGIPTIIAKIIDNGIANQNIAYIKQMGIVIVIISIIGVVGSVLLGYCSAKVSTSVTRDIRNDIFEKSQEFSHTEYNKFGISSMITRTTNDAFQIQQFVNILLRTALLTPVMFIISIIMTIRTSVELSIVLAISVPFIIIGVAIIAKVSQAISSKQQKGLDKLNLISRENLTGIRVIRAFGNDDYETERFEKTNTYYANVSKKLFKLMSITQPAFFLLLNIAVLAVFWISSEKINIGELQVGQLVAFLEYLFHAMFSIMLFSMVFIMYPRAEVSANRIKELLNEEPLIKNPENGIKENENKGIIEFDNVTFTYPDGEASVLKDISFTAKTGETVAFIGSTGSGKSTLINLIPRFYDVTEGSIKINGVDIREYDLKALRKKIGFIPQKSLLFTGSIANNIRFGKHKAGESELEYSAKVAQAYEFISKKPRKFDELISEGGANVSGGQKQRLSIARAIIRRPEIYIFDDSFSALDFKTDAILRAKLKKETKDAIVLIVAQRISSIIDADKIIVLNEGQVVGMGTHKELLKNCEIYYEIATSQLKKEELE

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Crispr_ID: NZ_CP045224_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045224_6

983212-983386

Orphan

Consensus_repeat	Method
TATATGTTTAGAAGCTGTAAAAAAA	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP045224_6

>merge|NZ_CP045224|6|983212-983386|CRISPRCasFinder
TATATGTATAGAAGCAGTAAGAGGTTCATTTGAAGAACTTGAAATAAAAGAAATATTAAGTTATGTAAAGATACCAACAGAAAGAATATTTGTAGAAGCAGTAAAGCAAAATGGAAAAATTCTTAAATATGTAGAAAATCAGACAGAATTAATATGTTTAGAGGCAGTAAGAGAA

>NZ_CP045224|6|4|983212-983386|CRISPRCasFinder
TATATGTATAGAAGCAGTAAGAGGT	TCATTTGAAGAACTTGAAATAAAAGAAATATTAAGTTATGTAAAGATACCAACAGAAAG
AATATTTGTAGAAGCAGTAAAGCAA	AATGGAAAAATTCTTAAATATGTAGAAAATCAGACAGAATT
AATATGTTTAGAGGCAGTAAGAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045224.1\|WP_003422896.1\|978747_980460_+\|phosphoenolpyruvate--protein-phosphotransferase	unknown	unknown	gnl\|CDD\|224006
NZ_CP045224.1\|WP_003422914.1\|988992_991443_+\|single-stranded-DNA-specific-exonuclease-RecJ	unknown	unknown	gnl\|CDD\|273193
NZ_CP045224.1\|WP_003422918.1\|991455_991968_+\|adenine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|235028
NZ_CP045224.1\|WP_003422891.1\|974766_976500_+\|N-6-DNA-methylase	unknown	unknown	gnl\|CDD\|380294
NZ_CP045224.1\|WP_003422898.1\|981251_981917_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_003422924.1\|994737_995352_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293792
NZ_CP045224.1\|WP_003422923.1\|994273_994723_+\|D-tyrosyl-tRNA(Tyr)-deacylase	unknown	unknown	gnl\|CDD\|235383
NZ_CP045224.1\|WP_003422907.1\|985112_986492_+\|thioether-cross-link-forming-SCIFF-peptide-maturase	unknown	unknown	gnl\|CDD\|274892
NZ_CP045224.1\|WP_003422884.1\|970874_971519_+\|di-trans,poly-cis-decaprenylcistransferase	unknown	unknown	gnl\|CDD\|259850
NZ_CP045224.1\|WP_003422882.1\|970265_970736_-\|DUF4358-domain-containing-protein	unknown	unknown	gnl\|CDD\|379531
NZ_CP045224.1\|WP_003422888.1\|972778_974326_+\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|238923
NZ_CP045224.1\|WP_003422909.1\|986520_987018_+\|gamma-carbonic-anhydrase-family-protein	unknown	unknown	gnl\|CDD\|100051
NZ_CP045224.1\|WP_003422889.1\|974328_974727_+\|Rrf2-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224870
NZ_CP045224.1\|WP_003422886.1\|971561_972467_+\|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl\|CDD\|119407
NZ_CP045224.1\|WP_003422903.1\|984666_984813_+\|cyclic-lactone-autoinducer-peptide	unknown	unknown	gnl\|CDD\|275064
NZ_CP045224.1\|WP_003422921.1\|992041_994249_+\|bifunctional-(p)ppGpp-synthetase/guanosine-3',5'-bis(diphosphate)-3'-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|223394
NZ_CP045224.1\|WP_003422895.1\|978134_978395_+\|HPr-family-phosphocarrier-protein	unknown	unknown	gnl\|CDD\|376329
NZ_CP045224.1\|WP_003422893.1\|976731_977943_+\|patatin-like-phospholipase-family-protein	unknown	unknown	gnl\|CDD\|132848
NZ_CP045224.1\|WP_003422926.1\|995442_996999_+\|coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236187
NZ_CP045224.1\|WP_003422911.1\|987315_988980_+\|AarF/ABC1/UbiB-kinase-family-protein	unknown	unknown	gnl\|CDD\|223733

Protein	Function_ID	Function_description	E-value
NZ_CP045224.1\|WP_003422896.1\|978747_980460_+\|phosphoenolpyruvate--protein-phosphotransferase	gnl\|CDD\|224006	COG1080, PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism].	0
NZ_CP045224.1\|WP_003422914.1\|988992_991443_+\|single-stranded-DNA-specific-exonuclease-RecJ	gnl\|CDD\|273193	TIGR00644, recJ, single-stranded-DNA-specific exonuclease RecJ. All proteins in this family are 5'-3' single-strand DNA exonucleases. These proteins are used in some aspects of mismatch repair, recombination, and recombinational repair. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP045224.1\|WP_003422918.1\|991455_991968_+\|adenine-phosphoribosyltransferase	gnl\|CDD\|235028	PRK02304, PRK02304, adenine phosphoribosyltransferase; Provisional.	1.93617e-100
NZ_CP045224.1\|WP_003422891.1\|974766_976500_+\|N-6-DNA-methylase	gnl\|CDD\|380294	NF033452, BREX_1_MTaseX, BREX-1 system adenine-specific DNA-methyltransferase PglX. This protein, PglX, is a site-specific DNA methyltransferase associated BREX (bacteriophage exclusion) type 1 systems. The phage resistance appears not to be through restriction-modification, as phage DNA appears not to get degraded, but it does manage to inhibit phage replication.	2.22622e-17
NZ_CP045224.1\|WP_003422924.1\|994737_995352_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293792	cd06262, metallo-hydrolase-like_MBL-fold, mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases which can catalyze the hydrolysis of a wide range of beta-lactam antibiotics, hydroxyacylglutathione hydrolases (also called glyoxalase II) which hydrolyze S-d-lactoylglutathione to d-lactate in the second step of the glycoxlase system, AHL lactonases which catalyze the hydrolysis and opening of the homoserine lactone rings of acyl homoserine lactones (AHLs), persulfide dioxygenase which catalyze the oxidation of glutathione persulfide to glutathione and persulfite in the mitochondria, flavodiiron proteins which catalyze the reduction of oxygen and/or nitric oxide to water or nitrous oxide respectively, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J which has both 5'-3' exoribonucleolytic and endonucleolytic activity and ribonuclease Z which catalyzes the endonucleolytic removal of the 3' extension of the majority of tRNA precursors, cyclic nucleotide phosphodiesterases which decompose cyclic adenosine and guanosine 3', 5'-monophosphate (cAMP and cGMP) respectively, insecticide hydrolases, and proteins required for natural transformation competence. The diversity of biological roles is reflected in variations in the active site metallo-chemistry, for example classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, human persulfide dioxygenase ETHE1 is a mono-iron binding member of the superfamily; Arabidopsis thaliana hydroxyacylglutathione hydrolases incorporates iron, manganese, and zinc in its dinuclear metal binding site, and flavodiiron proteins contains a diiron site.	7.83179e-73
NZ_CP045224.1\|WP_003422923.1\|994273_994723_+\|D-tyrosyl-tRNA(Tyr)-deacylase	gnl\|CDD\|235383	PRK05273, PRK05273, D-tyrosyl-tRNA(Tyr) deacylase; Provisional.	4.5057e-99
NZ_CP045224.1\|WP_003422907.1\|985112_986492_+\|thioether-cross-link-forming-SCIFF-peptide-maturase	gnl\|CDD\|274892	TIGR03974, six-Cys-in-45_modification_radical_SAM_protein, SCIFF radical SAM maturase. Members of this protein family are predicted radical SAM enzymes universally associated with Six Cysteines in Forty-Five protein, or SCIFF (family TIGR03973), a predicted ribosomal natural product precursor that is nearly universal in the class Clostridia. Similarity of this family to radical SAM maturases (PqqE and subtilosin A maturase) found in the vicinity of other peptide precursors suggests this protein is the SCIFF radical SAM maturase. [Cellular processes, Biosynthesis of natural products].	0
NZ_CP045224.1\|WP_003422884.1\|970874_971519_+\|di-trans,poly-cis-decaprenylcistransferase	gnl\|CDD\|259850	cd00475, Cis_IPPS, Cis (Z)-Isoprenyl Diphosphate Synthases. Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.	1.5916e-60
NZ_CP045224.1\|WP_003422882.1\|970265_970736_-\|DUF4358-domain-containing-protein	gnl\|CDD\|379531	pfam14270, DUF4358, Domain of unknown function (DUF4358). This domain family is found in bacteria, and is approximately 110 amino acids in length.	5.32255e-05
NZ_CP045224.1\|WP_003422888.1\|972778_974326_+\|EAL-domain-containing-protein	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	1.59544e-88
NZ_CP045224.1\|WP_003422909.1\|986520_987018_+\|gamma-carbonic-anhydrase-family-protein	gnl\|CDD\|100051	cd04645, LbH_gamma_CA_like, Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism, involving the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide, followed by the regeneration of the active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. They are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionary distinct groups - alpha, beta and gamma carbonic anhydrases - which show no significant sequence identity or structural similarity. Gamma CAs are trimeric enzymes with left-handed parallel beta helix (LbH) structural domain.	2.27481e-80
NZ_CP045224.1\|WP_003422889.1\|974328_974727_+\|Rrf2-family-transcriptional-regulator	gnl\|CDD\|224870	COG1959, COG1959, Predicted transcriptional regulator [Transcription].	5.29636e-10
NZ_CP045224.1\|WP_003422886.1\|971561_972467_+\|N-acetylmuramoyl-L-alanine-amidase	gnl\|CDD\|119407	cd02696, MurNAc-LAA, N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino acids in certain cell wall glycopeptides. These proteins are Zn-dependent peptidases with highly conserved residues involved in cation co-ordination. MurNAc-LAA in this family is one of several peptidoglycan hydrolases (PGHs) found in bacterial and bacteriophage or prophage genomes that are involved in the degradation of the peptidoglycan. In Escherichia coli, there are five MurNAc-LAAs present: AmiA, AmiB, AmiC and AmiD that are periplasmic, and AmpD that is cytoplasmic. Three of these (AmiA, AmiB and AmiC) belong to this family, the other two (AmiD and AmpD) do not. E. coli AmiA, AmiB and AmiC play an important role in cleaving the septum to release daughter cells after cell division. In general, bacterial MurNAc-LAAs are members of the bacterial autolytic system and carry a signal peptide in their N-termini that allows their transport across the cytoplasmic membrane. However, the bacteriophage MurNAc-LAAs are endolysins since these phage-encoded enzymes break down bacterial peptidoglycan at the terminal stage of the phage reproduction cycle. As opposed to autolysins, almost all endolysins have no signal peptides and their translocation through the cytoplasmic membrane is thought to proceed with the help of phage-encoded holin proteins. The amidase catalytic module is fused to another functional module (cell wall binding module or CWBM) either at the N- or C-terminus, which is responsible for high affinity binding of the protein to the cell wall.	4.49831e-72
NZ_CP045224.1\|WP_003422903.1\|984666_984813_+\|cyclic-lactone-autoinducer-peptide	gnl\|CDD\|275064	TIGR04223, quorum_AgrD, cyclic lactone autoinducer peptide. Members of this family of short peptides are precursors to thiolactone (unless Cys is replaced by Ser) cyclic autoinducer peptides, used in quorum-sensing systems in Gram-positive bacteria. The best characterized is the AgrD precursor, processed by the AgrB protein. Nearby proteins regularly encountered include a histidine kinase and a response regulator. This model is related to pfam05931 but is newer and currently broader in scope.	6.35203e-08
NZ_CP045224.1\|WP_003422921.1\|992041_994249_+\|bifunctional-(p)ppGpp-synthetase/guanosine-3',5'-bis(diphosphate)-3'-pyrophosphohydrolase	gnl\|CDD\|223394	COG0317, SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription].	0
NZ_CP045224.1\|WP_003422895.1\|978134_978395_+\|HPr-family-phosphocarrier-protein	gnl\|CDD\|376329	pfam00381, PTS-HPr, PTS HPr component phosphorylation site.	1.66602e-32
NZ_CP045224.1\|WP_003422893.1\|976731_977943_+\|patatin-like-phospholipase-family-protein	gnl\|CDD\|132848	cd07209, Pat_hypo_Ecoli_Z1214_like, Hypothetical patatin similar to Z1214 protein of Escherichia coli. Patatin-like phospholipase similar to Z1214 protein of Escherichia coli. This family predominantly consists of bacterial patatin glycoproteins and some representatives from eukaryotes and archaea. The patatin protein accounts for up to 40% of the total soluble protein in potato tubers. Patatin is a storage protein, but it also has the enzymatic activity of a lipid acyl hydrolase, catalyzing the cleavage of fatty acids from membrane lipids. Members of this family have also been found in vertebrates.	2.49293e-60
NZ_CP045224.1\|WP_003422926.1\|995442_996999_+\|coproporphyrinogen-III-oxidase	gnl\|CDD\|236187	PRK08207, PRK08207, coproporphyrinogen III oxidase; Provisional.	0
NZ_CP045224.1\|WP_003422911.1\|987315_988980_+\|AarF/ABC1/UbiB-kinase-family-protein	gnl\|CDD\|223733	COG0661, AarF, Predicted unusual protein kinase [General function prediction only].	7.00807e-141

>NZ_CP045224.1|WP_003422898.1|981251_981917_-|hypothetical-protein
MKGKIVQYNFADIEEEVYSLDYAIAWNTDEENVNIIPFTNKFCKESIESFCLGKIDNFVEILNEGFVENHHYVHLDKMISVPKKKVNLVYQQDTHGYLLRDDNGNLIPAKITSEQSKSISSKMELFCAGEEKCLINILLKADPSYILDVDSIKDKNILNLGYESIDRYKEYNFDNDKILIFFINKKRYSVIMKKTNNSDNDLVSRNNAIKELFTNKAVNLN
>NZ_CP045224.1|WP_003422896.1|978747_980460_+|phosphoenolpyruvate--protein-phosphotransferase
MAYKGIGASPGVALGKALVVEHSELVIEKKSIDNVEAEIAKLENAVAVSKDELVKVKEKASEELGAEEAEIFEAHLLVLEDPELIGSAIDKIKTENVNAEYALNEIKEMFVSMFESMDNEYMKERAADIKDVTNRILRHILGIKVVDLSALSEEVVLIAHDLTPSDTATMNKKMVLGFLTDIGGRTSHTAIMSRTLEIAAIVGLNDITSKVKDGDFVVFNGDTGEVIVNPDKETINKYTELKAKYEDERKALQLLKGKPSVTLDGKHVELAGNIGTPNDIEGLIKNDAEGVGLYRTEFLYMDRDSFPTEEVQYEAYKAVLEGMDGKPIVIRTLDIGGDKELSYLNMEPEMNPFLGYRAIRLCLDRKDIFKTQLRALYRASVHGRLRIMFPMISSLEELLQAKEVVKEVLAELDSEGVAYAKDVEIGMMIEVPSAAVISDVLAKHVDFFSIGTNDLIQYTCAVDRMNQKISYLYNQFNPAVLRLIKTVIDNAHKEGKWAGMCGESAGDQKMIPILLGMGLDEFSMSPISILPARKLITSVKESDMKKLADEVLNMGTAEEIKSYIEKTFNI
>NZ_CP045224.1|WP_003422895.1|978134_978395_+|HPr-family-phosphocarrier-protein
MEKVVSIKNASGLHARPAGMFVKKAAEFKSTVEVVAKDKTVNAKSIMGIMSLGLAQGEELKLVVNGEDEEVALAAMVELVESGFGE
>NZ_CP045224.1|WP_003422893.1|976731_977943_+|patatin-like-phospholipase-family-protein
MKGLVLEGGGTKGAYQIGAYKALRELGIEFQGVTGTSIGALNGAYIIQNDIEVMEDIWLNYDYTHFMNIDRETYERFKNVDFTTKNLNAVFELINKARKNEGIDISPLRQLMETTLNEDIIRKSKKDFGLVTVWWDKKINPYPLYIEDIPKGRLIDYLIASSSLPIFQTNMMDDKLYLDGMFCDNMPIGLLEDKGYEDVVVIRLIDDFIGKMNLNRHQNINIKTIIPSEYLGGSLNKDRDNVEKNIRLGYLDTMKAYERCTGIKYYFDVEYKYNEEYCFDKFRSMSNETIQYICNLLNIKRDVSLRTVMESIIPKLGEVLGLPKDFSYKDLFYCIYEKKLEENNINRIKLYDFNKVIDVVNTNIDSNRKLASNFEIRPKISIKKNKNTKLLTNCIIKDIKNQS
>NZ_CP045224.1|WP_003422891.1|974766_976500_+|N-6-DNA-methylase
MDDISQDNFLLSKEYENSLDVDTKKASGIYYTPKIIVDYIVKKTLKNHDIIKNPYPRILDISCGCGNFLLEVYDILYDLFEENIYELKKKYDENYWTVDNIHSHILNYCIYGADIDEKAISILKDSLINKKVVNDLDESDIKINLFCCDSLKKKWRYKFDYIVGNPPYIGHKKLEKKYKKFLLEKYSEVYKDKADLYFCFYKKIIDILKQGGIGSVITPRYFLESLSGKDLREYIKSNVNVQEIVDFLGANIFKNIGVSSCILTFDKKKTKKTYIDVFKIKNEDICINKFEILEELLKSSKFEHFNINQRLLSDEWILVNKEDETFYNKIQEKCKYSLEDIAISFQGIITGCDKAFILSKDDVKLNLVDDKFLKCWIKSKNINKYVVDKSEYRLIYSNDIDNENTNKKILDEIIGIYKTKLENRRECKSGIRKWYELQWGREKLFFERKKIMYPYKSNENRFAIDYDNNFSSADVYSFFIKEEYLGIFSYEYLVGILNSSIYDKYFKITAKKMSKNIYDYYPNKVMKIRIFRDNNYDEIENLSKQIISILLNKSIDKGKVEKLQIKMDNLIMDSLGI
>NZ_CP045224.1|WP_003422889.1|974328_974727_+|Rrf2-family-transcriptional-regulator
MISEDVDYSIRIIRAIFNNGEDNPIDAKMILKNEEIPTLTLYRLLRKLCANNILTFNKEDGKKYMLNVSLDTISLRTIVEAIDGKIYINKCTRYVSNCSNCLKGCKVNRELLEIEKEIYKLLSRKSIRQILE
>NZ_CP045224.1|WP_003422888.1|972778_974326_+|EAL-domain-containing-protein
MNKNSMTKIYSLNKIIFIIIGILGIVLLTRHIGVGVKVLILILLILFSINVFISHLKIQVYEDKINLGLINNPDKFINITKDENFLKHVQNYIISNEKENCVMACFDLCRLKLINDIYGYELGDEVLNNILSNLKYYFGKEAIYVKLKSAVFVLIIKLEDREQKIPYLVNLIKNKIVILNQIDNFKMDINIEASIGIYKFNNNEIDIKKAIDNADMARIKSKRLKHIEYVEFDNAMEEEIQSIMKIERDLFLAIKNKEFVIHYQPKVDSSTGNIIGSEALIRWLHPSLGMIAPNKFIPIAEKNGLINNIGRWLIQEVFGTINKWILEGINVLPVSINLSRVELYKNDLVDFFKLMFNTYNIPKELIELEITETTALRDVKFISERLYEIKSLGMNISLDDFGVGNSNFINLKGIPLDVIKIDRSLILDIVTNTKTKFMVKAIVNLSHDLNVTVICEGVEDMNQVKVLSELGCNFIQGYVFFKPLDEINYKRLLTDGSYINLEDTLLDKCMAVEEE
>NZ_CP045224.1|WP_003422886.1|971561_972467_+|N-acetylmuramoyl-L-alanine-amidase
MKKKLLDGKITLIICKSVKIYTKKGEEMSKGNNNNNSRNKSKKTSHLNRKKRKLNKKKLAVLICFTVLFLFIAFKVTQGVVALVKSMDKGNKTSQQQNVNSEQFDLGNEEENKNKKYTVFIDPGHGGNDKGTESKTSHRYEKDLNLQIAKKLANKLSKQKDIQVVVSRTDDTYISLKDRAILANNSSADVLVSIHLNAEKNGNTATGIETWYRNKATDGSKELAQTVQSTIVSYVKVRDRGIVENNFEVLRESNMPAILIECGFLTTPSDEQKIINEKYQEQLAEGIVQGVLSYLDSKGNK
>NZ_CP045224.1|WP_003422884.1|970874_971519_+|di-trans,poly-cis-decaprenylcistransferase
MRIPKHVGIIPDGNRRWASQNGMTKDKGYESGIDPGLESYRLCRDLGCEEVTFYGFTTDNTRRPSVQTKAFTKACIDAANILIDEGAALLVVGNTKSPMFPEELLPYTNRIKAKEGQIKANLLVNYGWYWDLNNISGVENVNKNNIQDYIQSFDVSRLDLIIRWGGRRRLSGFLPVQSIYADFYVIDNYWPDFKSDDIKDAFSWYDTQDVTLGG
>NZ_CP045224.1|WP_003422882.1|970265_970736_-|DUF4358-domain-containing-protein
MKKILILFFSIILSLGMVSCSSSGDYKNVSTSKIKKALKSSDLLIKESKIFDAKDFNYFNDVEEYIIQGFVINSSEKLSLEDIIVIKTDEVDKIYKTLENYKKDMIQAPFGEGHGEKINSEIANNTIIEKAGRYVYLISAENAPQIENKILSIIKK
>NZ_CP045224.1|WP_003422903.1|984666_984813_+|cyclic-lactone-autoinducer-peptide
MKKFIVRFMKFASSLALSTAILSANSTCPWIIHQPKVPKEISNLKKKN
>NZ_CP045224.1|WP_003422907.1|985112_986492_+|thioether-cross-link-forming-SCIFF-peptide-maturase
MSMIHKFSMNGYNIVLDVNGGAVHVLDDVAYDLLDFYKEKSKEEILEILKSKYQEEKINEAYEEILNLEKEGLLYTEDTYQYHPSFVHREPVVKALCLNVAHDCNLKCKYCFAAQGDFGGEKELMSFEVGKAAIDYLIANSGSRKNLEIDFFGGEPLMNFEVVKQLVYYGRSVEKDYNKNIRFTITTNGVLLNDEIIDYINENMHNVVLSLDGRKEVNDNMRPTLNDKGSYDITLPRFKKLVEKRAKDKYYYIRGTFTRDNLDFSKDVMHFADLGFKLTSVEPVVGDESNPYALREEDLPKIFEEYEKFAVEYADRQLQGDGFKFFHFMIDLNQGPCVIKRITGCGAGNEYLSITPNGDIYPCHQFVGNEEFKMANIFDEEIVLPENLKNMFREAHVYTKEECKQCWNKFYCSGGCHANAINFNNDISKPYELGCEMQRKRTECSIMIQAKLMLEGATN
>NZ_CP045224.1|WP_003422909.1|986520_987018_+|gamma-carbonic-anhydrase-family-protein
MIRDYLEDKPLIDESVFVAKSADVIGNVKIGKDSSIWYNAVVRGDEGPITIGENTNIQDCSIVHGDTETIIGNNVTVGHRSIVHGCKISDNVLIGMGSIILDNAEIGEYTLIGAGTLITSNKKFPPGVLIMGSPGKVVRELTEEDKRYIDESYEWYLEAAQNQKY
>NZ_CP045224.1|WP_003422911.1|987315_988980_+|AarF/ABC1/UbiB-kinase-family-protein
MRISYRNLKRYREIGYVLIKYGFSFIVERLNIEGIAYKIPLFDPPEEIKNMTTGERIKRVLEELGPTYIKIGQILSTRKDLLDQDIIDEISKLRDDVEKFDSNIAIEIFKEEVGLSIEEIFLEFKEEPIAAASIGQVYEGILRTGEEVIVKIQRPNIEKIIKSDLEILRTIANTLKDLKKDFNLDLVQMIEEFQTQLMRELDYTFEAINATKFSRIFKNSDEVYIPKIYSEYNTKKILVMEKVNGTKLSDVEKIKRLGYNTKTIVEIGVRSFFTQVLSHGFFHADPHPGNIFVVAKNKIAYIDFGMIGIIDNKTLNQLNEIALAGVEKNVDKIIYLLMEMDALNGEADIKGLRQDLLYLIHYYYDISIEKINVTDILNELFRFFRQYKIVMPAQFVTLAKTVITLEGTSRTLNTDFSFGSMGKEFMKHHYKSKFNPKNVVLSSRQNIEEILLDIKTIPKQLKAILKNIERNNIKMQIEDVKMTRLENCIIELTSQISLSLVLASIIVGSSLIIASPNIENNIWIKFTAIAGFFISFIIGLCLVIRSIRSKYKKD
>NZ_CP045224.1|WP_003422914.1|988992_991443_+|single-stranded-DNA-specific-exonuclease-RecJ
MKKWILKYKGKIEESEFSKKLNISPEICQILKNRGICTEKDSEIFMNPSLDYLRDPFLMKDMQKAVDRIKSAVEKNEKIWIYGDYDVDGVSSTSILCLYFKSIGYHVDYYIPNRLEEGYGINEDAIKLISSRGCDLIISVDCGITSVSEVNTANDLGIDVIITDHHECQNEIPVAFAVINPKQEDCNYPFDSLCGCGVAFKIIQALTPKEEFKTSMYDYLEIVTLATICDIVPLIDENRIIVKNGLKSMKEGKNIGLRELIKVCGVESDKIGSSHIGFAIGPRINASGRLGYSYLGVELFTTQSQEEAVEIASILKEKNNERQMIEAKMYHEAEEMLKSNSRYNDDKVLVLAKEGWQHGIIGIVASKLTEKYYKPTILLSIENGEATGSARSIKGFNIFEALVKCKDLMTKFGGHEQAAGLSLDSDNVEILANEINKFADYNLTEDDMIENINVEFELQENVINLNLVEELHKLEPFGLNNPNPRFIVRNYILKDLKVIGKNQQHLKLNIEKEKSYECIGFNMSHLKSMYKVGDKVDVLFQLDENNYMGNRKVQFLLKDIRLARPKSASNDKLSLKLMSKIIPKDTQSLYNISVSDFELFDGNTDINIFDYFEKDTLIISNSINGFYRAMSDISLIDLDFNINYNIIEDVSKNTDKLELIFSPNIDKIDLKRYNNIILYDYLYNKGEYSYIYENKREESEIIKYYNKTDLLYLKNVVSNIVPSRDEFITIYKQALIKKEIDLDMVNIRGTFNVIPLKFFTILNVFRELNLLDFNLNYEKNSVLIRILPKPQKKLDLNESLILNNLKNLEKQYNSSY
>NZ_CP045224.1|WP_003422918.1|991455_991968_+|adenine-phosphoribosyltransferase
MDLKNFIRNIDDFPKPGIDFKDVTTLFKDGDAFKYAVDSIVEELKDKGVDLVIGPEARGFLMGTPVAYALGVGFVPIRKPGKLPGEVESYEYGLEYGTDTLEIHKDAIKKGQKVAIVDDLLATGGTMEAAAKLVEKLGGEVVSMQFLIELKFLNGREKLSNYDVNSLIKY
>NZ_CP045224.1|WP_003422921.1|992041_994249_+|bifunctional-(p)ppGpp-synthetase/guanosine-3',5'-bis(diphosphate)-3'-pyrophosphohydrolase
MHDKELQEIIEKIKVYAPNANFEMVEKAYNLAKKAHEGQYRKSGEPYFIHPLAVANILIEMELDIETITAGLLHDVVEDTEYTYEDIKKEFGKEVADLVDGVTKLGQIKYRSKEETQSENLRKMFLAMAKDIRVILIKLADRLHNMRTLKYMPPEKAKYKAKETLEIYGGIAHRLGISKIKWELEDRALRFMDPEGYYDLVSRVSMKRSQREDYIQGIVELLKDKFKDLSIPCDVYGRPKHFYSIYRKMQKKHKTFEEIFDLTAVRILVDNVKDCYAVLGIVHTLWRPIPGRFKDYIAMPKPNMYQSLHTTVVGPDGEPLEIQIRTHEMHNIAENGIAAHWKYKEGISSKESKVEEKLQWLRQMMEWEKDLKDPQEFMDALKEDVFNSQVYVFTPKGDVIELPAESTPIDFAYRVHTNVGNKCVGAKIDGRIVPIDYKLQNGNIVEVLTSSNSNGPSRDWLNIVKTPNAKSRIRQFFKKERREENVDRGNTILEREFKKHDIPQKDPLVEKYMALVAKKFNQPSVEDLIATVGYGGIMSSQVVSKVKDLYLKEVKKAKKEQQIQEEDLNKHNISETEYSKKRKKNASQGIIVKGLDNILVRFAKCCNPLPGDEIVGYITKGRGVAIHRADCPNANNNGDFFQNRLVEVSWSSAGKGKFEAEIQIKAIDRRGIVNEITHIVAMDKLSLNGINARKGKDSIVSINLLVEVNDTEELKILMKKLKAIPGVESIYRMTN
>NZ_CP045224.1|WP_003422923.1|994273_994723_+|D-tyrosyl-tRNA(Tyr)-deacylase
MRAVVQRVSSSKVTVDENTIGQINKGLLVLLGVTHDDKSSDVDYMIDKILNLRIFEDENDKMNLSLMDIGGELLVVSQFTLYGDCRKGRRPGFSNAAKPELANNLYEEFVKKAKDKGVTVGTGQFAAHMMVELTNDGPVTILLDSSKSF
>NZ_CP045224.1|WP_003422924.1|994737_995352_+|MBL-fold-metallo-hydrolase
MIIKKFVDSYFGVNTYVLGDEKTKKCAVIDPGGSLVETLSFVKENELNIEYIILTHGHGDHIGYVKDIKEKTGAKVVAHIDEKELLNDKNKNLSYTMRCGAQEFDADIYVNDKDKLELGELKMTFLHTPGHTQGCMCIRVEDEMFTGDTLFAGSIGRTDLYSGNFNQMEKSLKKLCKYEDAVRVYPGHGPTSTLGVEKKTNPYM
>NZ_CP045224.1|WP_003422926.1|995442_996999_+|coproporphyrinogen-III-oxidase
MLYVFLKGHDYKYEVAELIKLFTSEFKFNDFNANNNMESKNLINRLIYENGVLFSSTVYYENGNLKYESIQNIENMNLEFLDGFDGNKTIEEFLNSLDNESKRNFKKLCKESIKKSMFVVLKQIFNSYVPWGILTGIRPVKIVHNLMDKNLDDNSIRTILKDNYFIIDEKIDLALEIAKRERLFMYPIDKNKISLYVSIPFCPTRCVYCSFPSNSLKQFGHLKREYVYKLIEEIKGFAKIIRETNKEVETLYIGGGTPTTLDEEELDLLINSLFNELDLSKIREFTVEAGRPDTITEQKLRVLKKHNVSRISINPQTMNDDTLVKIGREHRVSDLVDCFNMARRMGFDNINMDIILGLIDEDLNMVKNTLDEIKKLSPESLTVHTLAIKRASNLNINMDRYKEHLTQYEEMVKMIDLSMKYAKDMGLNPYYMYRQKHMLGNLENIGYAKEGYECIYNIQIMEEKQSNYALGAGAISKFVYVDEDRIERVENVKNVEQYIERVDEMIKRKKEEVYKNVD

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Crispr_ID: NZ_CP045224_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045224_5

982522-983105

Orphan

Consensus_repeat	Method
TATATGTTTAGAAGCTGTAAAAAAA	CRISPRCasFinder

8 spacers

The CRISPR arrays of NZ_CP045224_5

>merge|NZ_CP045224|5|982522-983105|CRISPRCasFinder
AGTATGTATGGAAGCAGTAAAACAGACATATAAAGCTCTTAAGTATATAACAAATCAAAATGAGGATATTTGTATAGAAGCAGTAAAACAGAACTACAGAGCTTTGTACTACATAAATAATAAGACAGAAAATGTACTAATTGAAGCTATAAAAAATGCATCAACTTATGATGTTATGGAAGTATTTAAATTTGTAGAAGAGCAGACAGAAGATGTATGTCTAGCATTTATAGAAAGAGCATCTAAAAATGATGTCGCAGAGATACTAAAAGGAATAAAAGAGCAAACTCCAGCTATATGTTTAGAAGCTGTAAAAAAAGACGGAAAATCTTTAGCTTATGTAAAGGAACAAAGTAATAGTATATGTTTAGAAGCTGTAAAAGAAAACTACAGTGCACTGTCTTGTGTAAAAGAGCAAACAGAAGAAATATGTATAGAAGCAGTAAAACAGAATGACTTTGCATTGTATTATGTAAATGAACAGACAGAAAAAATATGTATGGAAGCAGTAAAAAGAAGTTATATGGCTCTACAGTATGTAAATAAGCAAACAGAAGAGATTTGTTTGGAAGCAGTAAGAATTG

>NZ_CP045224|5|3|982522-983105|CRISPRCasFinder
AGTATGTATGGAAGCAGTAAAACAG	ACATATAAAGCTCTTAAGTATATAACAAATCAAAATGAGGA
TATTTGTATAGAAGCAGTAAAACAG	AACTACAGAGCTTTGTACTACATAAATAATAAGACAGAAAA
TGTACTAATTGAAGCTATAAAAAAT	GCATCAACTTATGATGTTATGGAAGTATTTAAATTTGTAGAAGAGCAGACAGAAGA
TGTATGTCTAGCATTTATAGAAAGA	GCATCTAAAAATGATGTCGCAGAGATACTAAAAGGAATAAAAGAGCAAACTCCAGC
TATATGTTTAGAAGCTGTAAAAAAA	GACGGAAAATCTTTAGCTTATGTAAAGGAACAAAGTAATAG
TATATGTTTAGAAGCTGTAAAAGAA	AACTACAGTGCACTGTCTTGTGTAAAAGAGCAAACAGAAGA
AATATGTATAGAAGCAGTAAAACAG	AATGACTTTGCATTGTATTATGTAAATGAACAGACAGAAAA
AATATGTATGGAAGCAGTAAAAAGA	AGTTATATGGCTCTACAGTATGTAAATAAGCAAACAGAAGA
GATTTGTTTGGAAGCAGTAAGAATTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045224.1\|WP_003422896.1\|978747_980460_+\|phosphoenolpyruvate--protein-phosphotransferase	unknown	unknown	gnl\|CDD\|224006
NZ_CP045224.1\|WP_003422914.1\|988992_991443_+\|single-stranded-DNA-specific-exonuclease-RecJ	unknown	unknown	gnl\|CDD\|273193
NZ_CP045224.1\|WP_003422918.1\|991455_991968_+\|adenine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|235028
NZ_CP045224.1\|WP_003422891.1\|974766_976500_+\|N-6-DNA-methylase	unknown	unknown	gnl\|CDD\|380294
NZ_CP045224.1\|WP_003422898.1\|981251_981917_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_003422924.1\|994737_995352_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293792
NZ_CP045224.1\|WP_003422923.1\|994273_994723_+\|D-tyrosyl-tRNA(Tyr)-deacylase	unknown	unknown	gnl\|CDD\|235383
NZ_CP045224.1\|WP_003422907.1\|985112_986492_+\|thioether-cross-link-forming-SCIFF-peptide-maturase	unknown	unknown	gnl\|CDD\|274892
NZ_CP045224.1\|WP_003422884.1\|970874_971519_+\|di-trans,poly-cis-decaprenylcistransferase	unknown	unknown	gnl\|CDD\|259850
NZ_CP045224.1\|WP_003422882.1\|970265_970736_-\|DUF4358-domain-containing-protein	unknown	unknown	gnl\|CDD\|379531
NZ_CP045224.1\|WP_003422888.1\|972778_974326_+\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|238923
NZ_CP045224.1\|WP_003422909.1\|986520_987018_+\|gamma-carbonic-anhydrase-family-protein	unknown	unknown	gnl\|CDD\|100051
NZ_CP045224.1\|WP_003422889.1\|974328_974727_+\|Rrf2-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224870
NZ_CP045224.1\|WP_003422886.1\|971561_972467_+\|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl\|CDD\|119407
NZ_CP045224.1\|WP_003422903.1\|984666_984813_+\|cyclic-lactone-autoinducer-peptide	unknown	unknown	gnl\|CDD\|275064
NZ_CP045224.1\|WP_003422921.1\|992041_994249_+\|bifunctional-(p)ppGpp-synthetase/guanosine-3',5'-bis(diphosphate)-3'-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|223394
NZ_CP045224.1\|WP_003422895.1\|978134_978395_+\|HPr-family-phosphocarrier-protein	unknown	unknown	gnl\|CDD\|376329
NZ_CP045224.1\|WP_003422893.1\|976731_977943_+\|patatin-like-phospholipase-family-protein	unknown	unknown	gnl\|CDD\|132848
NZ_CP045224.1\|WP_003422926.1\|995442_996999_+\|coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236187
NZ_CP045224.1\|WP_003422911.1\|987315_988980_+\|AarF/ABC1/UbiB-kinase-family-protein	unknown	unknown	gnl\|CDD\|223733

Protein	Function_ID	Function_description	E-value
NZ_CP045224.1\|WP_003422896.1\|978747_980460_+\|phosphoenolpyruvate--protein-phosphotransferase	gnl\|CDD\|224006	COG1080, PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism].	0
NZ_CP045224.1\|WP_003422914.1\|988992_991443_+\|single-stranded-DNA-specific-exonuclease-RecJ	gnl\|CDD\|273193	TIGR00644, recJ, single-stranded-DNA-specific exonuclease RecJ. All proteins in this family are 5'-3' single-strand DNA exonucleases. These proteins are used in some aspects of mismatch repair, recombination, and recombinational repair. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP045224.1\|WP_003422918.1\|991455_991968_+\|adenine-phosphoribosyltransferase	gnl\|CDD\|235028	PRK02304, PRK02304, adenine phosphoribosyltransferase; Provisional.	1.93617e-100
NZ_CP045224.1\|WP_003422891.1\|974766_976500_+\|N-6-DNA-methylase	gnl\|CDD\|380294	NF033452, BREX_1_MTaseX, BREX-1 system adenine-specific DNA-methyltransferase PglX. This protein, PglX, is a site-specific DNA methyltransferase associated BREX (bacteriophage exclusion) type 1 systems. The phage resistance appears not to be through restriction-modification, as phage DNA appears not to get degraded, but it does manage to inhibit phage replication.	2.22622e-17
NZ_CP045224.1\|WP_003422924.1\|994737_995352_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293792	cd06262, metallo-hydrolase-like_MBL-fold, mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases which can catalyze the hydrolysis of a wide range of beta-lactam antibiotics, hydroxyacylglutathione hydrolases (also called glyoxalase II) which hydrolyze S-d-lactoylglutathione to d-lactate in the second step of the glycoxlase system, AHL lactonases which catalyze the hydrolysis and opening of the homoserine lactone rings of acyl homoserine lactones (AHLs), persulfide dioxygenase which catalyze the oxidation of glutathione persulfide to glutathione and persulfite in the mitochondria, flavodiiron proteins which catalyze the reduction of oxygen and/or nitric oxide to water or nitrous oxide respectively, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J which has both 5'-3' exoribonucleolytic and endonucleolytic activity and ribonuclease Z which catalyzes the endonucleolytic removal of the 3' extension of the majority of tRNA precursors, cyclic nucleotide phosphodiesterases which decompose cyclic adenosine and guanosine 3', 5'-monophosphate (cAMP and cGMP) respectively, insecticide hydrolases, and proteins required for natural transformation competence. The diversity of biological roles is reflected in variations in the active site metallo-chemistry, for example classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, human persulfide dioxygenase ETHE1 is a mono-iron binding member of the superfamily; Arabidopsis thaliana hydroxyacylglutathione hydrolases incorporates iron, manganese, and zinc in its dinuclear metal binding site, and flavodiiron proteins contains a diiron site.	7.83179e-73
NZ_CP045224.1\|WP_003422923.1\|994273_994723_+\|D-tyrosyl-tRNA(Tyr)-deacylase	gnl\|CDD\|235383	PRK05273, PRK05273, D-tyrosyl-tRNA(Tyr) deacylase; Provisional.	4.5057e-99
NZ_CP045224.1\|WP_003422907.1\|985112_986492_+\|thioether-cross-link-forming-SCIFF-peptide-maturase	gnl\|CDD\|274892	TIGR03974, six-Cys-in-45_modification_radical_SAM_protein, SCIFF radical SAM maturase. Members of this protein family are predicted radical SAM enzymes universally associated with Six Cysteines in Forty-Five protein, or SCIFF (family TIGR03973), a predicted ribosomal natural product precursor that is nearly universal in the class Clostridia. Similarity of this family to radical SAM maturases (PqqE and subtilosin A maturase) found in the vicinity of other peptide precursors suggests this protein is the SCIFF radical SAM maturase. [Cellular processes, Biosynthesis of natural products].	0
NZ_CP045224.1\|WP_003422884.1\|970874_971519_+\|di-trans,poly-cis-decaprenylcistransferase	gnl\|CDD\|259850	cd00475, Cis_IPPS, Cis (Z)-Isoprenyl Diphosphate Synthases. Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.	1.5916e-60
NZ_CP045224.1\|WP_003422882.1\|970265_970736_-\|DUF4358-domain-containing-protein	gnl\|CDD\|379531	pfam14270, DUF4358, Domain of unknown function (DUF4358). This domain family is found in bacteria, and is approximately 110 amino acids in length.	5.32255e-05
NZ_CP045224.1\|WP_003422888.1\|972778_974326_+\|EAL-domain-containing-protein	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	1.59544e-88
NZ_CP045224.1\|WP_003422909.1\|986520_987018_+\|gamma-carbonic-anhydrase-family-protein	gnl\|CDD\|100051	cd04645, LbH_gamma_CA_like, Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism, involving the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide, followed by the regeneration of the active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. They are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionary distinct groups - alpha, beta and gamma carbonic anhydrases - which show no significant sequence identity or structural similarity. Gamma CAs are trimeric enzymes with left-handed parallel beta helix (LbH) structural domain.	2.27481e-80
NZ_CP045224.1\|WP_003422889.1\|974328_974727_+\|Rrf2-family-transcriptional-regulator	gnl\|CDD\|224870	COG1959, COG1959, Predicted transcriptional regulator [Transcription].	5.29636e-10
NZ_CP045224.1\|WP_003422886.1\|971561_972467_+\|N-acetylmuramoyl-L-alanine-amidase	gnl\|CDD\|119407	cd02696, MurNAc-LAA, N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino acids in certain cell wall glycopeptides. These proteins are Zn-dependent peptidases with highly conserved residues involved in cation co-ordination. MurNAc-LAA in this family is one of several peptidoglycan hydrolases (PGHs) found in bacterial and bacteriophage or prophage genomes that are involved in the degradation of the peptidoglycan. In Escherichia coli, there are five MurNAc-LAAs present: AmiA, AmiB, AmiC and AmiD that are periplasmic, and AmpD that is cytoplasmic. Three of these (AmiA, AmiB and AmiC) belong to this family, the other two (AmiD and AmpD) do not. E. coli AmiA, AmiB and AmiC play an important role in cleaving the septum to release daughter cells after cell division. In general, bacterial MurNAc-LAAs are members of the bacterial autolytic system and carry a signal peptide in their N-termini that allows their transport across the cytoplasmic membrane. However, the bacteriophage MurNAc-LAAs are endolysins since these phage-encoded enzymes break down bacterial peptidoglycan at the terminal stage of the phage reproduction cycle. As opposed to autolysins, almost all endolysins have no signal peptides and their translocation through the cytoplasmic membrane is thought to proceed with the help of phage-encoded holin proteins. The amidase catalytic module is fused to another functional module (cell wall binding module or CWBM) either at the N- or C-terminus, which is responsible for high affinity binding of the protein to the cell wall.	4.49831e-72
NZ_CP045224.1\|WP_003422903.1\|984666_984813_+\|cyclic-lactone-autoinducer-peptide	gnl\|CDD\|275064	TIGR04223, quorum_AgrD, cyclic lactone autoinducer peptide. Members of this family of short peptides are precursors to thiolactone (unless Cys is replaced by Ser) cyclic autoinducer peptides, used in quorum-sensing systems in Gram-positive bacteria. The best characterized is the AgrD precursor, processed by the AgrB protein. Nearby proteins regularly encountered include a histidine kinase and a response regulator. This model is related to pfam05931 but is newer and currently broader in scope.	6.35203e-08
NZ_CP045224.1\|WP_003422921.1\|992041_994249_+\|bifunctional-(p)ppGpp-synthetase/guanosine-3',5'-bis(diphosphate)-3'-pyrophosphohydrolase	gnl\|CDD\|223394	COG0317, SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription].	0
NZ_CP045224.1\|WP_003422895.1\|978134_978395_+\|HPr-family-phosphocarrier-protein	gnl\|CDD\|376329	pfam00381, PTS-HPr, PTS HPr component phosphorylation site.	1.66602e-32
NZ_CP045224.1\|WP_003422893.1\|976731_977943_+\|patatin-like-phospholipase-family-protein	gnl\|CDD\|132848	cd07209, Pat_hypo_Ecoli_Z1214_like, Hypothetical patatin similar to Z1214 protein of Escherichia coli. Patatin-like phospholipase similar to Z1214 protein of Escherichia coli. This family predominantly consists of bacterial patatin glycoproteins and some representatives from eukaryotes and archaea. The patatin protein accounts for up to 40% of the total soluble protein in potato tubers. Patatin is a storage protein, but it also has the enzymatic activity of a lipid acyl hydrolase, catalyzing the cleavage of fatty acids from membrane lipids. Members of this family have also been found in vertebrates.	2.49293e-60
NZ_CP045224.1\|WP_003422926.1\|995442_996999_+\|coproporphyrinogen-III-oxidase	gnl\|CDD\|236187	PRK08207, PRK08207, coproporphyrinogen III oxidase; Provisional.	0
NZ_CP045224.1\|WP_003422911.1\|987315_988980_+\|AarF/ABC1/UbiB-kinase-family-protein	gnl\|CDD\|223733	COG0661, AarF, Predicted unusual protein kinase [General function prediction only].	7.00807e-141

>NZ_CP045224.1|WP_003422898.1|981251_981917_-|hypothetical-protein
MKGKIVQYNFADIEEEVYSLDYAIAWNTDEENVNIIPFTNKFCKESIESFCLGKIDNFVEILNEGFVENHHYVHLDKMISVPKKKVNLVYQQDTHGYLLRDDNGNLIPAKITSEQSKSISSKMELFCAGEEKCLINILLKADPSYILDVDSIKDKNILNLGYESIDRYKEYNFDNDKILIFFINKKRYSVIMKKTNNSDNDLVSRNNAIKELFTNKAVNLN
>NZ_CP045224.1|WP_003422896.1|978747_980460_+|phosphoenolpyruvate--protein-phosphotransferase
MAYKGIGASPGVALGKALVVEHSELVIEKKSIDNVEAEIAKLENAVAVSKDELVKVKEKASEELGAEEAEIFEAHLLVLEDPELIGSAIDKIKTENVNAEYALNEIKEMFVSMFESMDNEYMKERAADIKDVTNRILRHILGIKVVDLSALSEEVVLIAHDLTPSDTATMNKKMVLGFLTDIGGRTSHTAIMSRTLEIAAIVGLNDITSKVKDGDFVVFNGDTGEVIVNPDKETINKYTELKAKYEDERKALQLLKGKPSVTLDGKHVELAGNIGTPNDIEGLIKNDAEGVGLYRTEFLYMDRDSFPTEEVQYEAYKAVLEGMDGKPIVIRTLDIGGDKELSYLNMEPEMNPFLGYRAIRLCLDRKDIFKTQLRALYRASVHGRLRIMFPMISSLEELLQAKEVVKEVLAELDSEGVAYAKDVEIGMMIEVPSAAVISDVLAKHVDFFSIGTNDLIQYTCAVDRMNQKISYLYNQFNPAVLRLIKTVIDNAHKEGKWAGMCGESAGDQKMIPILLGMGLDEFSMSPISILPARKLITSVKESDMKKLADEVLNMGTAEEIKSYIEKTFNI
>NZ_CP045224.1|WP_003422895.1|978134_978395_+|HPr-family-phosphocarrier-protein
MEKVVSIKNASGLHARPAGMFVKKAAEFKSTVEVVAKDKTVNAKSIMGIMSLGLAQGEELKLVVNGEDEEVALAAMVELVESGFGE
>NZ_CP045224.1|WP_003422893.1|976731_977943_+|patatin-like-phospholipase-family-protein
MKGLVLEGGGTKGAYQIGAYKALRELGIEFQGVTGTSIGALNGAYIIQNDIEVMEDIWLNYDYTHFMNIDRETYERFKNVDFTTKNLNAVFELINKARKNEGIDISPLRQLMETTLNEDIIRKSKKDFGLVTVWWDKKINPYPLYIEDIPKGRLIDYLIASSSLPIFQTNMMDDKLYLDGMFCDNMPIGLLEDKGYEDVVVIRLIDDFIGKMNLNRHQNINIKTIIPSEYLGGSLNKDRDNVEKNIRLGYLDTMKAYERCTGIKYYFDVEYKYNEEYCFDKFRSMSNETIQYICNLLNIKRDVSLRTVMESIIPKLGEVLGLPKDFSYKDLFYCIYEKKLEENNINRIKLYDFNKVIDVVNTNIDSNRKLASNFEIRPKISIKKNKNTKLLTNCIIKDIKNQS
>NZ_CP045224.1|WP_003422891.1|974766_976500_+|N-6-DNA-methylase
MDDISQDNFLLSKEYENSLDVDTKKASGIYYTPKIIVDYIVKKTLKNHDIIKNPYPRILDISCGCGNFLLEVYDILYDLFEENIYELKKKYDENYWTVDNIHSHILNYCIYGADIDEKAISILKDSLINKKVVNDLDESDIKINLFCCDSLKKKWRYKFDYIVGNPPYIGHKKLEKKYKKFLLEKYSEVYKDKADLYFCFYKKIIDILKQGGIGSVITPRYFLESLSGKDLREYIKSNVNVQEIVDFLGANIFKNIGVSSCILTFDKKKTKKTYIDVFKIKNEDICINKFEILEELLKSSKFEHFNINQRLLSDEWILVNKEDETFYNKIQEKCKYSLEDIAISFQGIITGCDKAFILSKDDVKLNLVDDKFLKCWIKSKNINKYVVDKSEYRLIYSNDIDNENTNKKILDEIIGIYKTKLENRRECKSGIRKWYELQWGREKLFFERKKIMYPYKSNENRFAIDYDNNFSSADVYSFFIKEEYLGIFSYEYLVGILNSSIYDKYFKITAKKMSKNIYDYYPNKVMKIRIFRDNNYDEIENLSKQIISILLNKSIDKGKVEKLQIKMDNLIMDSLGI
>NZ_CP045224.1|WP_003422889.1|974328_974727_+|Rrf2-family-transcriptional-regulator
MISEDVDYSIRIIRAIFNNGEDNPIDAKMILKNEEIPTLTLYRLLRKLCANNILTFNKEDGKKYMLNVSLDTISLRTIVEAIDGKIYINKCTRYVSNCSNCLKGCKVNRELLEIEKEIYKLLSRKSIRQILE
>NZ_CP045224.1|WP_003422888.1|972778_974326_+|EAL-domain-containing-protein
MNKNSMTKIYSLNKIIFIIIGILGIVLLTRHIGVGVKVLILILLILFSINVFISHLKIQVYEDKINLGLINNPDKFINITKDENFLKHVQNYIISNEKENCVMACFDLCRLKLINDIYGYELGDEVLNNILSNLKYYFGKEAIYVKLKSAVFVLIIKLEDREQKIPYLVNLIKNKIVILNQIDNFKMDINIEASIGIYKFNNNEIDIKKAIDNADMARIKSKRLKHIEYVEFDNAMEEEIQSIMKIERDLFLAIKNKEFVIHYQPKVDSSTGNIIGSEALIRWLHPSLGMIAPNKFIPIAEKNGLINNIGRWLIQEVFGTINKWILEGINVLPVSINLSRVELYKNDLVDFFKLMFNTYNIPKELIELEITETTALRDVKFISERLYEIKSLGMNISLDDFGVGNSNFINLKGIPLDVIKIDRSLILDIVTNTKTKFMVKAIVNLSHDLNVTVICEGVEDMNQVKVLSELGCNFIQGYVFFKPLDEINYKRLLTDGSYINLEDTLLDKCMAVEEE
>NZ_CP045224.1|WP_003422886.1|971561_972467_+|N-acetylmuramoyl-L-alanine-amidase
MKKKLLDGKITLIICKSVKIYTKKGEEMSKGNNNNNSRNKSKKTSHLNRKKRKLNKKKLAVLICFTVLFLFIAFKVTQGVVALVKSMDKGNKTSQQQNVNSEQFDLGNEEENKNKKYTVFIDPGHGGNDKGTESKTSHRYEKDLNLQIAKKLANKLSKQKDIQVVVSRTDDTYISLKDRAILANNSSADVLVSIHLNAEKNGNTATGIETWYRNKATDGSKELAQTVQSTIVSYVKVRDRGIVENNFEVLRESNMPAILIECGFLTTPSDEQKIINEKYQEQLAEGIVQGVLSYLDSKGNK
>NZ_CP045224.1|WP_003422884.1|970874_971519_+|di-trans,poly-cis-decaprenylcistransferase
MRIPKHVGIIPDGNRRWASQNGMTKDKGYESGIDPGLESYRLCRDLGCEEVTFYGFTTDNTRRPSVQTKAFTKACIDAANILIDEGAALLVVGNTKSPMFPEELLPYTNRIKAKEGQIKANLLVNYGWYWDLNNISGVENVNKNNIQDYIQSFDVSRLDLIIRWGGRRRLSGFLPVQSIYADFYVIDNYWPDFKSDDIKDAFSWYDTQDVTLGG
>NZ_CP045224.1|WP_003422882.1|970265_970736_-|DUF4358-domain-containing-protein
MKKILILFFSIILSLGMVSCSSSGDYKNVSTSKIKKALKSSDLLIKESKIFDAKDFNYFNDVEEYIIQGFVINSSEKLSLEDIIVIKTDEVDKIYKTLENYKKDMIQAPFGEGHGEKINSEIANNTIIEKAGRYVYLISAENAPQIENKILSIIKK
>NZ_CP045224.1|WP_003422903.1|984666_984813_+|cyclic-lactone-autoinducer-peptide
MKKFIVRFMKFASSLALSTAILSANSTCPWIIHQPKVPKEISNLKKKN
>NZ_CP045224.1|WP_003422907.1|985112_986492_+|thioether-cross-link-forming-SCIFF-peptide-maturase
MSMIHKFSMNGYNIVLDVNGGAVHVLDDVAYDLLDFYKEKSKEEILEILKSKYQEEKINEAYEEILNLEKEGLLYTEDTYQYHPSFVHREPVVKALCLNVAHDCNLKCKYCFAAQGDFGGEKELMSFEVGKAAIDYLIANSGSRKNLEIDFFGGEPLMNFEVVKQLVYYGRSVEKDYNKNIRFTITTNGVLLNDEIIDYINENMHNVVLSLDGRKEVNDNMRPTLNDKGSYDITLPRFKKLVEKRAKDKYYYIRGTFTRDNLDFSKDVMHFADLGFKLTSVEPVVGDESNPYALREEDLPKIFEEYEKFAVEYADRQLQGDGFKFFHFMIDLNQGPCVIKRITGCGAGNEYLSITPNGDIYPCHQFVGNEEFKMANIFDEEIVLPENLKNMFREAHVYTKEECKQCWNKFYCSGGCHANAINFNNDISKPYELGCEMQRKRTECSIMIQAKLMLEGATN
>NZ_CP045224.1|WP_003422909.1|986520_987018_+|gamma-carbonic-anhydrase-family-protein
MIRDYLEDKPLIDESVFVAKSADVIGNVKIGKDSSIWYNAVVRGDEGPITIGENTNIQDCSIVHGDTETIIGNNVTVGHRSIVHGCKISDNVLIGMGSIILDNAEIGEYTLIGAGTLITSNKKFPPGVLIMGSPGKVVRELTEEDKRYIDESYEWYLEAAQNQKY
>NZ_CP045224.1|WP_003422911.1|987315_988980_+|AarF/ABC1/UbiB-kinase-family-protein
MRISYRNLKRYREIGYVLIKYGFSFIVERLNIEGIAYKIPLFDPPEEIKNMTTGERIKRVLEELGPTYIKIGQILSTRKDLLDQDIIDEISKLRDDVEKFDSNIAIEIFKEEVGLSIEEIFLEFKEEPIAAASIGQVYEGILRTGEEVIVKIQRPNIEKIIKSDLEILRTIANTLKDLKKDFNLDLVQMIEEFQTQLMRELDYTFEAINATKFSRIFKNSDEVYIPKIYSEYNTKKILVMEKVNGTKLSDVEKIKRLGYNTKTIVEIGVRSFFTQVLSHGFFHADPHPGNIFVVAKNKIAYIDFGMIGIIDNKTLNQLNEIALAGVEKNVDKIIYLLMEMDALNGEADIKGLRQDLLYLIHYYYDISIEKINVTDILNELFRFFRQYKIVMPAQFVTLAKTVITLEGTSRTLNTDFSFGSMGKEFMKHHYKSKFNPKNVVLSSRQNIEEILLDIKTIPKQLKAILKNIERNNIKMQIEDVKMTRLENCIIELTSQISLSLVLASIIVGSSLIIASPNIENNIWIKFTAIAGFFISFIIGLCLVIRSIRSKYKKD
>NZ_CP045224.1|WP_003422914.1|988992_991443_+|single-stranded-DNA-specific-exonuclease-RecJ
MKKWILKYKGKIEESEFSKKLNISPEICQILKNRGICTEKDSEIFMNPSLDYLRDPFLMKDMQKAVDRIKSAVEKNEKIWIYGDYDVDGVSSTSILCLYFKSIGYHVDYYIPNRLEEGYGINEDAIKLISSRGCDLIISVDCGITSVSEVNTANDLGIDVIITDHHECQNEIPVAFAVINPKQEDCNYPFDSLCGCGVAFKIIQALTPKEEFKTSMYDYLEIVTLATICDIVPLIDENRIIVKNGLKSMKEGKNIGLRELIKVCGVESDKIGSSHIGFAIGPRINASGRLGYSYLGVELFTTQSQEEAVEIASILKEKNNERQMIEAKMYHEAEEMLKSNSRYNDDKVLVLAKEGWQHGIIGIVASKLTEKYYKPTILLSIENGEATGSARSIKGFNIFEALVKCKDLMTKFGGHEQAAGLSLDSDNVEILANEINKFADYNLTEDDMIENINVEFELQENVINLNLVEELHKLEPFGLNNPNPRFIVRNYILKDLKVIGKNQQHLKLNIEKEKSYECIGFNMSHLKSMYKVGDKVDVLFQLDENNYMGNRKVQFLLKDIRLARPKSASNDKLSLKLMSKIIPKDTQSLYNISVSDFELFDGNTDINIFDYFEKDTLIISNSINGFYRAMSDISLIDLDFNINYNIIEDVSKNTDKLELIFSPNIDKIDLKRYNNIILYDYLYNKGEYSYIYENKREESEIIKYYNKTDLLYLKNVVSNIVPSRDEFITIYKQALIKKEIDLDMVNIRGTFNVIPLKFFTILNVFRELNLLDFNLNYEKNSVLIRILPKPQKKLDLNESLILNNLKNLEKQYNSSY
>NZ_CP045224.1|WP_003422918.1|991455_991968_+|adenine-phosphoribosyltransferase
MDLKNFIRNIDDFPKPGIDFKDVTTLFKDGDAFKYAVDSIVEELKDKGVDLVIGPEARGFLMGTPVAYALGVGFVPIRKPGKLPGEVESYEYGLEYGTDTLEIHKDAIKKGQKVAIVDDLLATGGTMEAAAKLVEKLGGEVVSMQFLIELKFLNGREKLSNYDVNSLIKY
>NZ_CP045224.1|WP_003422921.1|992041_994249_+|bifunctional-(p)ppGpp-synthetase/guanosine-3',5'-bis(diphosphate)-3'-pyrophosphohydrolase
MHDKELQEIIEKIKVYAPNANFEMVEKAYNLAKKAHEGQYRKSGEPYFIHPLAVANILIEMELDIETITAGLLHDVVEDTEYTYEDIKKEFGKEVADLVDGVTKLGQIKYRSKEETQSENLRKMFLAMAKDIRVILIKLADRLHNMRTLKYMPPEKAKYKAKETLEIYGGIAHRLGISKIKWELEDRALRFMDPEGYYDLVSRVSMKRSQREDYIQGIVELLKDKFKDLSIPCDVYGRPKHFYSIYRKMQKKHKTFEEIFDLTAVRILVDNVKDCYAVLGIVHTLWRPIPGRFKDYIAMPKPNMYQSLHTTVVGPDGEPLEIQIRTHEMHNIAENGIAAHWKYKEGISSKESKVEEKLQWLRQMMEWEKDLKDPQEFMDALKEDVFNSQVYVFTPKGDVIELPAESTPIDFAYRVHTNVGNKCVGAKIDGRIVPIDYKLQNGNIVEVLTSSNSNGPSRDWLNIVKTPNAKSRIRQFFKKERREENVDRGNTILEREFKKHDIPQKDPLVEKYMALVAKKFNQPSVEDLIATVGYGGIMSSQVVSKVKDLYLKEVKKAKKEQQIQEEDLNKHNISETEYSKKRKKNASQGIIVKGLDNILVRFAKCCNPLPGDEIVGYITKGRGVAIHRADCPNANNNGDFFQNRLVEVSWSSAGKGKFEAEIQIKAIDRRGIVNEITHIVAMDKLSLNGINARKGKDSIVSINLLVEVNDTEELKILMKKLKAIPGVESIYRMTN
>NZ_CP045224.1|WP_003422923.1|994273_994723_+|D-tyrosyl-tRNA(Tyr)-deacylase
MRAVVQRVSSSKVTVDENTIGQINKGLLVLLGVTHDDKSSDVDYMIDKILNLRIFEDENDKMNLSLMDIGGELLVVSQFTLYGDCRKGRRPGFSNAAKPELANNLYEEFVKKAKDKGVTVGTGQFAAHMMVELTNDGPVTILLDSSKSF
>NZ_CP045224.1|WP_003422924.1|994737_995352_+|MBL-fold-metallo-hydrolase
MIIKKFVDSYFGVNTYVLGDEKTKKCAVIDPGGSLVETLSFVKENELNIEYIILTHGHGDHIGYVKDIKEKTGAKVVAHIDEKELLNDKNKNLSYTMRCGAQEFDADIYVNDKDKLELGELKMTFLHTPGHTQGCMCIRVEDEMFTGDTLFAGSIGRTDLYSGNFNQMEKSLKKLCKYEDAVRVYPGHGPTSTLGVEKKTNPYM
>NZ_CP045224.1|WP_003422926.1|995442_996999_+|coproporphyrinogen-III-oxidase
MLYVFLKGHDYKYEVAELIKLFTSEFKFNDFNANNNMESKNLINRLIYENGVLFSSTVYYENGNLKYESIQNIENMNLEFLDGFDGNKTIEEFLNSLDNESKRNFKKLCKESIKKSMFVVLKQIFNSYVPWGILTGIRPVKIVHNLMDKNLDDNSIRTILKDNYFIIDEKIDLALEIAKRERLFMYPIDKNKISLYVSIPFCPTRCVYCSFPSNSLKQFGHLKREYVYKLIEEIKGFAKIIRETNKEVETLYIGGGTPTTLDEEELDLLINSLFNELDLSKIREFTVEAGRPDTITEQKLRVLKKHNVSRISINPQTMNDDTLVKIGREHRVSDLVDCFNMARRMGFDNINMDIILGLIDEDLNMVKNTLDEIKKLSPESLTVHTLAIKRASNLNINMDRYKEHLTQYEEMVKMIDLSMKYAKDMGLNPYYMYRQKHMLGNLENIGYAKEGYECIYNIQIMEEKQSNYALGAGAISKFVYVDEDRIERVENVKNVEQYIERVDEMIKRKKEEVYKNVD

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Crispr_ID: NZ_CP045224_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045224_7

1068945-1071941

Orphan

I-A

Consensus_repeat	Method
GTTTTATATTAACTATGTGGTATGTAAAG	PILER-CR
GTTTTATATTAACTATGTGGTATGTAAAG	CRISPRCasFinder
GTTTTATATTAACTATGTGGTATGTAAAG	CRT

45 spacers

The CRISPR arrays of NZ_CP045224_7

>merge|NZ_CP045224|7|1068945-1071941|PILER-CR,CRISPRCasFinder,CRT
GTTTTATATTAACTATGTGGTATGTAAAGTAGACTGATATTCATCCATACTGATGATTCCTAAAGAAGTTTTATATTAACTATGTGGTATGTAAAGAGGGTTGAGTTCTGGCGTATTAAGAGGTGAGGAGCGTTTTATATTAACTATGTGGTATGTAAAGTGGAGAAGGTCTTGGATTAGCACCAATAGGTCATAGAGTTTTATATTAACTATGTGGTATGTAAAGAGTGAAAGCAAGGCTATTCCTAATTCTTGGAGTGGAGTTTTATATTAACTATGTGGTATGTAAAGAAATAAGTTTTGAAGCAGAATTTACACACAATAAACTAGTTTTATATTAACTATGTGGTATGTAAAGAAATAAAAGAATTAGGATTTACTCAACAATCAATTAAGTTTTATATTAACTATGTGGTATGTAAAGACCAATTTTTGTATGCTATATCACAATCTTTACTCTCGTTTTATATTAACTATGTGGTATGTAAAGTCTTCCACTTTAGGTTTATATGCTGACCTATACTTTGGTTTTATATTAACTATGTGGTATGTAAAGCTGCATTATCTACAAGTGGGTGGTTTTTTAAATTAGTGTTTTATATTAACTATGTGGTATGTAAAGAAGAAAGACAAACATGTTCAAAGTCATGTTCAAACAGTTTTATATTAACTATGTGGTATGTAAAGCGGCAAATAAGAGCAGTATATTCATCAGATTTAAATAGTTTTATATTAACTATGTGGTATGTAAAGGAGGTTGATGCTTATAGATTAAGTAAATTAGCTACTGGTTTTATATTAACTATGTGGTATGTAAAGGTTAGTGTATGTCCTGGTACTAACGCTACCTTCATTAGTTTTATATTAACTATGTGGTATGTAAAGTCATTATAACCCCAACCAACTACAGTTGCAGGGATTTGTTTTATATTAACTATGTGGTATGTAAAGTATAGCTAAATCTATTGTGGATTTAATTATTTCTGCCTCGTTTTATATTAACTATGTGGTATGTAAAGAACTCTTTTGCTATTCGTTTCACTACATTATTATCATGTTTTATATTAACTATGTGGTATGTAAAGAAAAGTAATGAGAGTTTAGAAGATAGAAGGTTTAGGAGTTTTATATTAACTATGTGGTATGTAAAGTTATTTTCTCTGATAATTCTACTAAGGTATTATTTAAAGTTTTATATTAACTATGTGGTATGTAAAGATATGACAGCACAAGGAACACCTACAGCACAAGCAGTTTTATATTAACTATGTGGTATGTAAAGAAAAACTAAAACAGTCTATGGCTATATGAAAATCTCGTTTTATATTAACTATGTGGTATGTAAAGAAGAAAATAAGACGTTCAAATCAAAAAAGACGAAGTAGTTTTATATTAACTATGTGGTATGTAAAGTCTATTCCAACATAAAGATACAAAGTAGTTTCTTTTTGTTTTATATTAACTATGTGGTATGTAAAGAAACAAATCATCACACAAGCAATTATTATGCTTACTAAGTTTTATATTAACTATGTGGTATGTAAAGGTCGTAAAACTTAAAGATGAAACAAAAGGAATGATTGTTTTATATTAACTATGTGGTATGTAAAGAGATTCGACGGAGAACTTTTATCTAATAAAGAAAAACGTTTTATATTAACTATGTGGTATGTAAAGATCACCTGGTGATATACCCCTCTATCATCTCCTGCTAGTTTTATATTAACTATGTGGTATGTAAAGTGGTTTGTTGCAACATATGTGTTCCTTCAACATATCCGTTTTATATTAACTATGTGGTATGTAAAGGAATCTGGAGCAGGTTTATAAGTTTCTGGATAGCTAGAGTTTTATATTAACTATGTGGTATGTAAAGAAAAAATATAAAAGAGCTAAGCACATGAAGGATAATGTTTTATATTAACTATGTGGTATGTAAAGTATGTTAAATTTGTTGATGAATTATATCCCAATTTTTAGTTTTATATTAACTATGTGGTATGTAAAGCACCTCTCACTACTATAGAATCTTTATCAACGCTAAGTTTTATATTAACTATGTGGTATGTAAAGGGAAGTATAATTTTTACTTTATCTCCATACTCAAAAAGTTTTATATTAACTATGTGGTATGTAAAGTGTATTGAGGGGTCGAAAATAAGTGTGTTCAAACTTAGTTTTATATTAACTATGTGGTATGTAAAGTTTGTAAATGTAACAGTTTTATCTAACATTTTACCGCGTTTTATATTAACTATGTGGTATGTAAAGGTATTTAGATATTGCAAGTAAATTACCTTCGGTATCGTTTTATATTAACTATGTGGTATGTAAAGTTTCATCTAATACCTCCTTGTTTTATCAAGAGGGTTAAGTTTTATATTAACTATGTGGTATGTAAAGATTAATTCAGAACTTGCACAGTTGTATATAGAACTTGTTTTATATTAACTATGTGGTATGTAAAGATATTCATATACTACATATTCTTTTCCTTCATCATTAAGTTTTATATTAACTATGTGGTATGTAAAGAGGTCTAAAATTTGTATTTAGACATACTAAGTTATTTGTTTTATATTAACTATGTGGTATGTAAAGTCACAAAAACAAGGAATACTTAAGTTAGCATCAATGAGTTTTATATTAACTATGTGGTATGTAAAGTCACAAAAACAAGGAATACTTAAGTTAGCATCAATGAGTTTTATATTAACTATGTGGTATGTAAAGTAGAGTATTGTTCTACAATTATATTTCCAACTGAACTGTTTTATATTAACTATGTGGTATGTAAAGTGAAGTTTTCTTTTAAATTATCATCCTGTATAGCCTTGTTTTATATTAACTATGTGGTATGTAAAGATACAGGAACAGGAGTCGGAACAGAAAAAAACGCCTCATTTTATATTAACTATGTGGTATGTAAAGGTTGTATTACCTCTGTAATTATTTTTTCCAAAATTACGCTTTATATTAACTAAGTGGTGAATTTAA

>NZ_CP045224|7|2|1068945-1071743|PILER-CR
GTTTTATATTAACTATGTGGTATGTAAAG	TAGACTGATATTCATCCATACTGATGATTCCTAAAGAA
GTTTTATATTAACTATGTGGTATGTAAAG	AGGGTTGAGTTCTGGCGTATTAAGAGGTGAGGAGC
GTTTTATATTAACTATGTGGTATGTAAAG	TGGAGAAGGTCTTGGATTAGCACCAATAGGTCATAGA
GTTTTATATTAACTATGTGGTATGTAAAG	AGTGAAAGCAAGGCTATTCCTAATTCTTGGAGTGGA
GTTTTATATTAACTATGTGGTATGTAAAG	AAATAAGTTTTGAAGCAGAATTTACACACAATAAACTA
GTTTTATATTAACTATGTGGTATGTAAAG	AAATAAAAGAATTAGGATTTACTCAACAATCAATTAA
GTTTTATATTAACTATGTGGTATGTAAAG	ACCAATTTTTGTATGCTATATCACAATCTTTACTCTC
GTTTTATATTAACTATGTGGTATGTAAAG	TCTTCCACTTTAGGTTTATATGCTGACCTATACTTTG
GTTTTATATTAACTATGTGGTATGTAAAG	CTGCATTATCTACAAGTGGGTGGTTTTTTAAATTAGT
GTTTTATATTAACTATGTGGTATGTAAAG	AAGAAAGACAAACATGTTCAAAGTCATGTTCAAACA
GTTTTATATTAACTATGTGGTATGTAAAG	CGGCAAATAAGAGCAGTATATTCATCAGATTTAAATA
GTTTTATATTAACTATGTGGTATGTAAAG	GAGGTTGATGCTTATAGATTAAGTAAATTAGCTACTG
GTTTTATATTAACTATGTGGTATGTAAAG	GTTAGTGTATGTCCTGGTACTAACGCTACCTTCATTA
GTTTTATATTAACTATGTGGTATGTAAAG	TCATTATAACCCCAACCAACTACAGTTGCAGGGATTT
GTTTTATATTAACTATGTGGTATGTAAAG	TATAGCTAAATCTATTGTGGATTTAATTATTTCTGCCTC
GTTTTATATTAACTATGTGGTATGTAAAG	AACTCTTTTGCTATTCGTTTCACTACATTATTATCAT
GTTTTATATTAACTATGTGGTATGTAAAG	AAAAGTAATGAGAGTTTAGAAGATAGAAGGTTTAGGA
GTTTTATATTAACTATGTGGTATGTAAAG	TTATTTTCTCTGATAATTCTACTAAGGTATTATTTAAA
GTTTTATATTAACTATGTGGTATGTAAAG	ATATGACAGCACAAGGAACACCTACAGCACAAGCA
GTTTTATATTAACTATGTGGTATGTAAAG	AAAAACTAAAACAGTCTATGGCTATATGAAAATCTC
GTTTTATATTAACTATGTGGTATGTAAAG	AAGAAAATAAGACGTTCAAATCAAAAAAGACGAAGTA
GTTTTATATTAACTATGTGGTATGTAAAG	TCTATTCCAACATAAAGATACAAAGTAGTTTCTTTTT
GTTTTATATTAACTATGTGGTATGTAAAG	AAACAAATCATCACACAAGCAATTATTATGCTTACTAA
GTTTTATATTAACTATGTGGTATGTAAAG	GTCGTAAAACTTAAAGATGAAACAAAAGGAATGATT
GTTTTATATTAACTATGTGGTATGTAAAG	AGATTCGACGGAGAACTTTTATCTAATAAAGAAAAAC
GTTTTATATTAACTATGTGGTATGTAAAG	ATCACCTGGTGATATACCCCTCTATCATCTCCTGCTA
GTTTTATATTAACTATGTGGTATGTAAAG	TGGTTTGTTGCAACATATGTGTTCCTTCAACATATCC
GTTTTATATTAACTATGTGGTATGTAAAG	GAATCTGGAGCAGGTTTATAAGTTTCTGGATAGCTAGA
GTTTTATATTAACTATGTGGTATGTAAAG	AAAAAATATAAAAGAGCTAAGCACATGAAGGATAAT
GTTTTATATTAACTATGTGGTATGTAAAG	TATGTTAAATTTGTTGATGAATTATATCCCAATTTTTA
GTTTTATATTAACTATGTGGTATGTAAAG	CACCTCTCACTACTATAGAATCTTTATCAACGCTAA
GTTTTATATTAACTATGTGGTATGTAAAG	GGAAGTATAATTTTTACTTTATCTCCATACTCAAAAA
GTTTTATATTAACTATGTGGTATGTAAAG	TGTATTGAGGGGTCGAAAATAAGTGTGTTCAAACTTA
GTTTTATATTAACTATGTGGTATGTAAAG	TTTGTAAATGTAACAGTTTTATCTAACATTTTACCGC
GTTTTATATTAACTATGTGGTATGTAAAG	GTATTTAGATATTGCAAGTAAATTACCTTCGGTATC
GTTTTATATTAACTATGTGGTATGTAAAG	TTTCATCTAATACCTCCTTGTTTTATCAAGAGGGTTAA
GTTTTATATTAACTATGTGGTATGTAAAG	ATTAATTCAGAACTTGCACAGTTGTATATAGAACTT
GTTTTATATTAACTATGTGGTATGTAAAG	ATATTCATATACTACATATTCTTTTCCTTCATCATTAA
GTTTTATATTAACTATGTGGTATGTAAAG	AGGTCTAAAATTTGTATTTAGACATACTAAGTTATTT
GTTTTATATTAACTATGTGGTATGTAAAG	TCACAAAAACAAGGAATACTTAAGTTAGCATCAATGA
GTTTTATATTAACTATGTGGTATGTAAAG	TCACAAAAACAAGGAATACTTAAGTTAGCATCAATGA
GTTTTATATTAACTATGTGGTATGTAAAG	TAGAGTATTGTTCTACAATTATATTTCCAACTGAACT
GTTTTATATTAACTATGTGGTATGTAAAG

>NZ_CP045224|7|5|1068945-1071941|CRISPRCasFinder
GTTTTATATTAACTATGTGGTATGTAAAG	TAGACTGATATTCATCCATACTGATGATTCCTAAAGAA
GTTTTATATTAACTATGTGGTATGTAAAG	AGGGTTGAGTTCTGGCGTATTAAGAGGTGAGGAGC
GTTTTATATTAACTATGTGGTATGTAAAG	TGGAGAAGGTCTTGGATTAGCACCAATAGGTCATAGA
GTTTTATATTAACTATGTGGTATGTAAAG	AGTGAAAGCAAGGCTATTCCTAATTCTTGGAGTGGA
GTTTTATATTAACTATGTGGTATGTAAAG	AAATAAGTTTTGAAGCAGAATTTACACACAATAAACTA
GTTTTATATTAACTATGTGGTATGTAAAG	AAATAAAAGAATTAGGATTTACTCAACAATCAATTAA
GTTTTATATTAACTATGTGGTATGTAAAG	ACCAATTTTTGTATGCTATATCACAATCTTTACTCTC
GTTTTATATTAACTATGTGGTATGTAAAG	TCTTCCACTTTAGGTTTATATGCTGACCTATACTTTG
GTTTTATATTAACTATGTGGTATGTAAAG	CTGCATTATCTACAAGTGGGTGGTTTTTTAAATTAGT
GTTTTATATTAACTATGTGGTATGTAAAG	AAGAAAGACAAACATGTTCAAAGTCATGTTCAAACA
GTTTTATATTAACTATGTGGTATGTAAAG	CGGCAAATAAGAGCAGTATATTCATCAGATTTAAATA
GTTTTATATTAACTATGTGGTATGTAAAG	GAGGTTGATGCTTATAGATTAAGTAAATTAGCTACTG
GTTTTATATTAACTATGTGGTATGTAAAG	GTTAGTGTATGTCCTGGTACTAACGCTACCTTCATTA
GTTTTATATTAACTATGTGGTATGTAAAG	TCATTATAACCCCAACCAACTACAGTTGCAGGGATTT
GTTTTATATTAACTATGTGGTATGTAAAG	TATAGCTAAATCTATTGTGGATTTAATTATTTCTGCCTC
GTTTTATATTAACTATGTGGTATGTAAAG	AACTCTTTTGCTATTCGTTTCACTACATTATTATCAT
GTTTTATATTAACTATGTGGTATGTAAAG	AAAAGTAATGAGAGTTTAGAAGATAGAAGGTTTAGGA
GTTTTATATTAACTATGTGGTATGTAAAG	TTATTTTCTCTGATAATTCTACTAAGGTATTATTTAAA
GTTTTATATTAACTATGTGGTATGTAAAG	ATATGACAGCACAAGGAACACCTACAGCACAAGCA
GTTTTATATTAACTATGTGGTATGTAAAG	AAAAACTAAAACAGTCTATGGCTATATGAAAATCTC
GTTTTATATTAACTATGTGGTATGTAAAG	AAGAAAATAAGACGTTCAAATCAAAAAAGACGAAGTA
GTTTTATATTAACTATGTGGTATGTAAAG	TCTATTCCAACATAAAGATACAAAGTAGTTTCTTTTT
GTTTTATATTAACTATGTGGTATGTAAAG	AAACAAATCATCACACAAGCAATTATTATGCTTACTAA
GTTTTATATTAACTATGTGGTATGTAAAG	GTCGTAAAACTTAAAGATGAAACAAAAGGAATGATT
GTTTTATATTAACTATGTGGTATGTAAAG	AGATTCGACGGAGAACTTTTATCTAATAAAGAAAAAC
GTTTTATATTAACTATGTGGTATGTAAAG	ATCACCTGGTGATATACCCCTCTATCATCTCCTGCTA
GTTTTATATTAACTATGTGGTATGTAAAG	TGGTTTGTTGCAACATATGTGTTCCTTCAACATATCC
GTTTTATATTAACTATGTGGTATGTAAAG	GAATCTGGAGCAGGTTTATAAGTTTCTGGATAGCTAGA
GTTTTATATTAACTATGTGGTATGTAAAG	AAAAAATATAAAAGAGCTAAGCACATGAAGGATAAT
GTTTTATATTAACTATGTGGTATGTAAAG	TATGTTAAATTTGTTGATGAATTATATCCCAATTTTTA
GTTTTATATTAACTATGTGGTATGTAAAG	CACCTCTCACTACTATAGAATCTTTATCAACGCTAA
GTTTTATATTAACTATGTGGTATGTAAAG	GGAAGTATAATTTTTACTTTATCTCCATACTCAAAAA
GTTTTATATTAACTATGTGGTATGTAAAG	TGTATTGAGGGGTCGAAAATAAGTGTGTTCAAACTTA
GTTTTATATTAACTATGTGGTATGTAAAG	TTTGTAAATGTAACAGTTTTATCTAACATTTTACCGC
GTTTTATATTAACTATGTGGTATGTAAAG	GTATTTAGATATTGCAAGTAAATTACCTTCGGTATC
GTTTTATATTAACTATGTGGTATGTAAAG	TTTCATCTAATACCTCCTTGTTTTATCAAGAGGGTTAA
GTTTTATATTAACTATGTGGTATGTAAAG	ATTAATTCAGAACTTGCACAGTTGTATATAGAACTT
GTTTTATATTAACTATGTGGTATGTAAAG	ATATTCATATACTACATATTCTTTTCCTTCATCATTAA
GTTTTATATTAACTATGTGGTATGTAAAG	AGGTCTAAAATTTGTATTTAGACATACTAAGTTATTT
GTTTTATATTAACTATGTGGTATGTAAAG	TCACAAAAACAAGGAATACTTAAGTTAGCATCAATGA
GTTTTATATTAACTATGTGGTATGTAAAG	TCACAAAAACAAGGAATACTTAAGTTAGCATCAATGA
GTTTTATATTAACTATGTGGTATGTAAAG	TAGAGTATTGTTCTACAATTATATTTCCAACTGAACT
GTTTTATATTAACTATGTGGTATGTAAAG	TGAAGTTTTCTTTTAAATTATCATCCTGTATAGCCTT
GTTTTATATTAACTATGTGGTATGTAAAG	ATACAGGAACAGGAGTCGGAACAGAAAAAAACGCCTC
ATTTTATATTAACTATGTGGTATGTAAAG	GTTGTATTACCTCTGTAATTATTTTTTCCAAAATTAC
GCTTTATATTAACTAAGTGGTGAATTTAA

>NZ_CP045224|7|4|1068945-1071941|CRT
GTTTTATATTAACTATGTGGTATGTAAAG	TAGACTGATATTCATCCATACTGATGATTCCTAAAGAA
GTTTTATATTAACTATGTGGTATGTAAAG	AGGGTTGAGTTCTGGCGTATTAAGAGGTGAGGAGC
GTTTTATATTAACTATGTGGTATGTAAAG	TGGAGAAGGTCTTGGATTAGCACCAATAGGTCATAGA
GTTTTATATTAACTATGTGGTATGTAAAG	AGTGAAAGCAAGGCTATTCCTAATTCTTGGAGTGGA
GTTTTATATTAACTATGTGGTATGTAAAG	AAATAAGTTTTGAAGCAGAATTTACACACAATAAACTA
GTTTTATATTAACTATGTGGTATGTAAAG	AAATAAAAGAATTAGGATTTACTCAACAATCAATTAA
GTTTTATATTAACTATGTGGTATGTAAAG	ACCAATTTTTGTATGCTATATCACAATCTTTACTCTC
GTTTTATATTAACTATGTGGTATGTAAAG	TCTTCCACTTTAGGTTTATATGCTGACCTATACTTTG
GTTTTATATTAACTATGTGGTATGTAAAG	CTGCATTATCTACAAGTGGGTGGTTTTTTAAATTAGT
GTTTTATATTAACTATGTGGTATGTAAAG	AAGAAAGACAAACATGTTCAAAGTCATGTTCAAACA
GTTTTATATTAACTATGTGGTATGTAAAG	CGGCAAATAAGAGCAGTATATTCATCAGATTTAAATA
GTTTTATATTAACTATGTGGTATGTAAAG	GAGGTTGATGCTTATAGATTAAGTAAATTAGCTACTG
GTTTTATATTAACTATGTGGTATGTAAAG	GTTAGTGTATGTCCTGGTACTAACGCTACCTTCATTA
GTTTTATATTAACTATGTGGTATGTAAAG	TCATTATAACCCCAACCAACTACAGTTGCAGGGATTT
GTTTTATATTAACTATGTGGTATGTAAAG	TATAGCTAAATCTATTGTGGATTTAATTATTTCTGCCTC
GTTTTATATTAACTATGTGGTATGTAAAG	AACTCTTTTGCTATTCGTTTCACTACATTATTATCAT
GTTTTATATTAACTATGTGGTATGTAAAG	AAAAGTAATGAGAGTTTAGAAGATAGAAGGTTTAGGA
GTTTTATATTAACTATGTGGTATGTAAAG	TTATTTTCTCTGATAATTCTACTAAGGTATTATTTAAA
GTTTTATATTAACTATGTGGTATGTAAAG	ATATGACAGCACAAGGAACACCTACAGCACAAGCA
GTTTTATATTAACTATGTGGTATGTAAAG	AAAAACTAAAACAGTCTATGGCTATATGAAAATCTC
GTTTTATATTAACTATGTGGTATGTAAAG	AAGAAAATAAGACGTTCAAATCAAAAAAGACGAAGTA
GTTTTATATTAACTATGTGGTATGTAAAG	TCTATTCCAACATAAAGATACAAAGTAGTTTCTTTTT
GTTTTATATTAACTATGTGGTATGTAAAG	AAACAAATCATCACACAAGCAATTATTATGCTTACTAA
GTTTTATATTAACTATGTGGTATGTAAAG	GTCGTAAAACTTAAAGATGAAACAAAAGGAATGATT
GTTTTATATTAACTATGTGGTATGTAAAG	AGATTCGACGGAGAACTTTTATCTAATAAAGAAAAAC
GTTTTATATTAACTATGTGGTATGTAAAG	ATCACCTGGTGATATACCCCTCTATCATCTCCTGCTA
GTTTTATATTAACTATGTGGTATGTAAAG	TGGTTTGTTGCAACATATGTGTTCCTTCAACATATCC
GTTTTATATTAACTATGTGGTATGTAAAG	GAATCTGGAGCAGGTTTATAAGTTTCTGGATAGCTAGA
GTTTTATATTAACTATGTGGTATGTAAAG	AAAAAATATAAAAGAGCTAAGCACATGAAGGATAAT
GTTTTATATTAACTATGTGGTATGTAAAG	TATGTTAAATTTGTTGATGAATTATATCCCAATTTTTA
GTTTTATATTAACTATGTGGTATGTAAAG	CACCTCTCACTACTATAGAATCTTTATCAACGCTAA
GTTTTATATTAACTATGTGGTATGTAAAG	GGAAGTATAATTTTTACTTTATCTCCATACTCAAAAA
GTTTTATATTAACTATGTGGTATGTAAAG	TGTATTGAGGGGTCGAAAATAAGTGTGTTCAAACTTA
GTTTTATATTAACTATGTGGTATGTAAAG	TTTGTAAATGTAACAGTTTTATCTAACATTTTACCGC
GTTTTATATTAACTATGTGGTATGTAAAG	GTATTTAGATATTGCAAGTAAATTACCTTCGGTATC
GTTTTATATTAACTATGTGGTATGTAAAG	TTTCATCTAATACCTCCTTGTTTTATCAAGAGGGTTAA
GTTTTATATTAACTATGTGGTATGTAAAG	ATTAATTCAGAACTTGCACAGTTGTATATAGAACTT
GTTTTATATTAACTATGTGGTATGTAAAG	ATATTCATATACTACATATTCTTTTCCTTCATCATTAA
GTTTTATATTAACTATGTGGTATGTAAAG	AGGTCTAAAATTTGTATTTAGACATACTAAGTTATTT
GTTTTATATTAACTATGTGGTATGTAAAG	TCACAAAAACAAGGAATACTTAAGTTAGCATCAATGA
GTTTTATATTAACTATGTGGTATGTAAAG	TCACAAAAACAAGGAATACTTAAGTTAGCATCAATGA
GTTTTATATTAACTATGTGGTATGTAAAG	TAGAGTATTGTTCTACAATTATATTTCCAACTGAACT
GTTTTATATTAACTATGTGGTATGTAAAG	TGAAGTTTTCTTTTAAATTATCATCCTGTATAGCCTT
GTTTTATATTAACTATGTGGTATGTAAAG	ATACAGGAACAGGAGTCGGAACAGAAAAAAACGCCTC
ATTTTATATTAACTATGTGGTATGTAAAG	GTTGTATTACCTCTGTAATTATTTTTTCCAAAATTAC
GCTTTATATTAACTAAGTGGTGAATTTAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045224.1\|WP_003424190.1\|1068513_1068666_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_003424163.1\|1077703_1077988_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_003424185.1\|1072655_1072844_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197775
NZ_CP045224.1\|WP_003415950.1\|1059929_1061120_+\|pyridoxal-phosphate-dependent-aminotransferase	unknown	unknown	gnl\|CDD\|224090
NZ_CP045224.1\|WP_003415953.1\|1062672_1063062_+\|DUF1232-domain-containing-protein	unknown	unknown	gnl\|CDD\|225876
NZ_CP045224.1\|WP_003424195.1\|1065362_1065527_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_003424162.1\|1078264_1078501_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|183035
NZ_CP045224.1\|WP_003424194.1\|1065750_1066596_-\|DUF4878-domain-containing-protein	unknown	unknown	gnl\|CDD\|379023
NZ_CP045224.1\|WP_003424180.1\|1073501_1073882_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_003424164.1\|1077123_1077381_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_003424166.1\|1075598_1076171_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378443
NZ_CP045224.1\|WP_003415961.1\|1064132_1064963_+\|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl\|CDD\|119407
NZ_CP045224.1\|WP_003415948.1\|1059238_1059535_+\|membrane-protein	unknown	unknown	gnl\|CDD\|182513
NZ_CP045224.1\|WP_003415957.1\|1063226_1063373_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_003424168.1\|1074418_1074613_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_003424182.1\|1073251_1073509_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_003424165.1\|1076613_1076985_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_003424184.1\|1073031_1073265_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_003424813.1\|1061567_1062569_+\|aspartate--ammonia-ligase	unknown	unknown	gnl\|CDD\|235456
NZ_CP045224.1\|WP_003421558.1\|1056849_1058037_+\|DUF3798-domain-containing-protein	unknown	unknown	gnl\|CDD\|378916

Protein	Function_ID	Function_description	E-value
NZ_CP045224.1\|WP_003424166.1\|1075598_1076171_+\|hypothetical-protein	gnl\|CDD\|378443	pfam10543, ORF6N, ORF6N domain. This domain was identified by Iyer and colleagues.	1.73523e-06
NZ_CP045224.1\|WP_003424185.1\|1072655_1072844_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	5.68544e-09
NZ_CP045224.1\|WP_003424162.1\|1078264_1078501_-\|hypothetical-protein	gnl\|CDD\|183035	PRK11199, tyrA, bifunctional chorismate mutase/prephenate dehydrogenase; Provisional.	0.00552244
NZ_CP045224.1\|WP_003415961.1\|1064132_1064963_+\|N-acetylmuramoyl-L-alanine-amidase	gnl\|CDD\|119407	cd02696, MurNAc-LAA, N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino acids in certain cell wall glycopeptides. These proteins are Zn-dependent peptidases with highly conserved residues involved in cation co-ordination. MurNAc-LAA in this family is one of several peptidoglycan hydrolases (PGHs) found in bacterial and bacteriophage or prophage genomes that are involved in the degradation of the peptidoglycan. In Escherichia coli, there are five MurNAc-LAAs present: AmiA, AmiB, AmiC and AmiD that are periplasmic, and AmpD that is cytoplasmic. Three of these (AmiA, AmiB and AmiC) belong to this family, the other two (AmiD and AmpD) do not. E. coli AmiA, AmiB and AmiC play an important role in cleaving the septum to release daughter cells after cell division. In general, bacterial MurNAc-LAAs are members of the bacterial autolytic system and carry a signal peptide in their N-termini that allows their transport across the cytoplasmic membrane. However, the bacteriophage MurNAc-LAAs are endolysins since these phage-encoded enzymes break down bacterial peptidoglycan at the terminal stage of the phage reproduction cycle. As opposed to autolysins, almost all endolysins have no signal peptides and their translocation through the cytoplasmic membrane is thought to proceed with the help of phage-encoded holin proteins. The amidase catalytic module is fused to another functional module (cell wall binding module or CWBM) either at the N- or C-terminus, which is responsible for high affinity binding of the protein to the cell wall.	5.73283e-32
NZ_CP045224.1\|WP_003415948.1\|1059238_1059535_+\|membrane-protein	gnl\|CDD\|182513	PRK10519, PRK10519, hypothetical protein; Provisional.	5.65553e-29
NZ_CP045224.1\|WP_003415950.1\|1059929_1061120_+\|pyridoxal-phosphate-dependent-aminotransferase	gnl\|CDD\|224090	COG1168, MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism].	2.77724e-179
NZ_CP045224.1\|WP_003415953.1\|1062672_1063062_+\|DUF1232-domain-containing-protein	gnl\|CDD\|225876	COG3339, COG3339, Uncharacterized conserved protein [Function unknown].	1.1592e-06
NZ_CP045224.1\|WP_003424194.1\|1065750_1066596_-\|DUF4878-domain-containing-protein	gnl\|CDD\|379023	pfam13026, DUF3887, Protein of unknown function (DUF3887). This domain family is found in bacteria and archaea, and is approximately 90 amino acids in length.	0.000618735
NZ_CP045224.1\|WP_003424813.1\|1061567_1062569_+\|aspartate--ammonia-ligase	gnl\|CDD\|235456	PRK05425, PRK05425, asparagine synthetase AsnA; Provisional.	0
NZ_CP045224.1\|WP_003421558.1\|1056849_1058037_+\|DUF3798-domain-containing-protein	gnl\|CDD\|378916	pfam12683, DUF3798, Protein of unknown function (DUF3798). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 247 and 417 amino acids in length. Most of the proteins in this family have an N-terminal lipoprotein attachment site. These proteins have distant similarity to periplasmic ligand binding families such as pfam02608, which suggests that this family have a similar role.	4.14246e-120

>NZ_CP045224.1|WP_003424190.1|1068513_1068666_+|hypothetical-protein
MDNFLQGILASLVASLIVYLTSKLFKKVKSHSGRSDFSFELEIKFKKNKH
>NZ_CP045224.1|WP_003424194.1|1065750_1066596_-|DUF4878-domain-containing-protein
MNITKRMTLLLTLLIVILITGCSPKESASEVAKKYIDKMNSGDYETAYSLLSKDSKKKISLENLEDFQNILVSTKRIISYKIGKEKIIKKYKHDGKEYKNVVKLEETFNIKNLLYKKDDSLKVNRYFVVENNKYKLLLYESFKKEFGINSMDLAQLKLNDFGLKYFKEVDLILKKAIAINPTDSTLYYAQACNYMNFDGFPDYPDATYNALDSINKSLKYLDKNDSDYKKNASNIYNLKGVILMFHKRFDEAQQDLNKSLYFNKDNEDPKSNLNTIKKHLK
>NZ_CP045224.1|WP_003424195.1|1065362_1065527_+|hypothetical-protein
MFGKPKESVRFLDFNDVAEKFGEKKAVAIFDAIAGKKSKEHIIKDIEKLVKNEV
>NZ_CP045224.1|WP_003415961.1|1064132_1064963_+|N-acetylmuramoyl-L-alanine-amidase
MKICITVGHSILKSGACTSADGVVNEYQYNKSLAPVLADTFRKEGHKVDVITCPERQFSSKNEEKSHKIPRVNSGGYDLLIELHLNASNGQGKGSEVLYYSNKGLEYATRVCDKLGTVFKNRGAKLDKNLYILNSSKPTAVLIESFFCDNKEDYESAKKLGYEGMAKLIVEGILNKGVANNEVKQMYKHTIVYSGDDKVSAEILGLYYKRAKENYLVSDIKDYEPHQTQNLYVIGGETCNKMKEMSNTTGEKFTEIYSDDVWSTMDKAIEFVKEKL
>NZ_CP045224.1|WP_003415957.1|1063226_1063373_-|hypothetical-protein
MLLYGTNKKTILDRLGHIDIKIAINKYSHVLEEVKKEISENLSKILFK
>NZ_CP045224.1|WP_003415953.1|1062672_1063062_+|DUF1232-domain-containing-protein
MDFLKIIINIVLDILKKILVRFKNAKFGLVFVFDLLKLPDFMTDKRINIADKIKVISVLIFTISYFVSGVDIIPEMIAGAFGFIDDVIVLIWSIGIVNEEINKYRVIAKKDKHSTIIENVNFSIKDEEE
>NZ_CP045224.1|WP_003424813.1|1061567_1062569_+|aspartate--ammonia-ligase
MSTIIPKDYKSSLNVIDTQIAIKKLKDFFEMRLSNELNLIRVSSPLFVLPETGANDNLNGEKAVSFDIPFMNKNAEIVQSLAKWKRLALKKYGFEVGSGLYTDMNAIRKNEELDNIHSLYVDQWDWELVIDKSSRNEKTLKDVVKRLYGVFKDTEIFVCSMYEDIKEILPEEITFITSQELEDMYPELSPKEREDKIVKEKKAVFITQIGKTLISGEKHDGRSPDYDDWELNGDILFYNPVLDSALELSSMGIRVDEESLDRQLKLAGCEERKEFDYHKMLLNGELPYTIGGGIGQSRICMYFLQKAHIGEVQVGVWPQDMIQNCSSAGIELL
>NZ_CP045224.1|WP_003415950.1|1059929_1061120_+|pyridoxal-phosphate-dependent-aminotransferase
MSKYNFDRVIDRVGTDCVKWDFRTNCSTKAQEDGLPFWIADMDFECAEPIIEALRKKVEHKIFGYSSNDSDKYFNAVCDWYKRRFNWEINRKDIIFSPGVVPAVAILVRILTNSNEGVIIQKPVYYPFEAKVKSNNREVVNNPLIYENGTYRMDYDDLEEKAKCSNNKVLILCSPHNPVGRVWREDELKKVVEICKKYDLWIIADEIHSDLIRKGFKHTPLQSLCPEYKDKIVTCIAPSKTFNLAGMQLSNIIVNNDELKKKYQEEVTAVGVATSPNPFAIVATIAAYNKSEDWLNELNEYLDNNIQFIDEYLKENLPKVKLVYPEGTYLAWLDFTAYGLNEVELEDLMFKKANVLFDEGYIFGKEGIGFERINVACPQSLLKECMGRLKTTFENL
>NZ_CP045224.1|WP_003415948.1|1059238_1059535_+|membrane-protein
MSEVVKKEVQVKKGNVIDAFIGGARNGFQISTNSMAPNVIFGFAIISVFNLTGLLDVIGTIFTPVMSIFGLPGVVATAIMTIVISRRGFPLLYTKTKM
>NZ_CP045224.1|WP_003421558.1|1056849_1058037_+|DUF3798-domain-containing-protein
MLRKITAFMLSICLIIGLTGCSLLVGKKDKEKVIDDFKVAVVTQPLSENKVQYNMVEEMAKEYEEENKIDKDKDGQTKVKQTIKHVVLPENFTSNIDSAINKIVKLADDKEVQAIVVSTDQAGLLPALQKVKEKRPEIITISAPMGDDKNQLSQFVDVNLGVSAEERGKVLAERSKEMGAKAFIHYASTDDLKDVNIAKRLEMIKETCKNIGLPFVQVNTPNINAEEDKNKVKQFLNEDIEKQVKKYGKDINVFGVNDYMDEVILTKALELKYIVAEQSNPSPIQTYPSVMGLKISKKDAQNYDKINDMISEKAKAFGMSNRLGGYPMPMDAFLPSLAIYLATEMVKQDLTQEDVCDPDYLEAFTELRFGIGSEFTPLTEVLYNYQSVILSQLIY
>NZ_CP045224.1|WP_003424185.1|1072655_1072844_-|helix-turn-helix-transcriptional-regulator
MTLQDRIKEERLKLGLNQVELSKKFNMTKQTVSNWESENRIQDTLMLTKLADFLCISRFSLG
>NZ_CP045224.1|WP_003424184.1|1073031_1073265_+|hypothetical-protein
MNTKKTKGIYKNGGLKVSRTAICSVCGELLVDGYGDEFTNTKIIDLHGREFVIIIYKNCLEELLRKCANGGISNDNN
>NZ_CP045224.1|WP_003424182.1|1073251_1073509_+|hypothetical-protein
MIIIRSQDRLDLMRVNRVEIDSKYVYAVFGEESNVREIGRYKSEERAIEVLSRIQDAIIAGTKFDIIKKDGVRYYKEKVFEMPVE
>NZ_CP045224.1|WP_003424180.1|1073501_1073882_+|hypothetical-protein
MNKEGSEMLKVEKYFSGSLGINIIEDDPTCRNYLALYCCLVGIERKGKKVIPRIDSMLSEFGVKSRCKRPHNNKLIRLINVKTGEVKEFKSIDSTACFLGLKQPAVSHILKRKTPSRSGWRAEYIK
>NZ_CP045224.1|WP_003424168.1|1074418_1074613_+|hypothetical-protein
MNILIYKYIVNEHRDEADELDRDYGEFKIFNGGKCFSGCGRNFYTLAKFKKMIITCPHYEKNIK
>NZ_CP045224.1|WP_003424166.1|1075598_1076171_+|hypothetical-protein
MNENLSKEIKILGTIEVEEMKFHDIEGGFGVGKKSMSVKDIDEIHNGKLKDINKNINNNRKRFKDMINTLDLKVSDLKSLSLEMGYSNQSYANANNIYLLPERDYSKRLKILEGKQYEKIVDGYFSMRKELNNPLLSASKELQAIFMLDKKQEFLETKIESVNEKLENFMDDAPLFNIEFESIVKIVLWK
>NZ_CP045224.1|WP_003424165.1|1076613_1076985_+|hypothetical-protein
MKKQIMALGLTGLIGLGGLGLLANKSFADTPNKLKGDTTVAQGLNKNATAKDVTEQVDTTIGKGLDKNAIVKDVVENNGEKSDTTVAPGLDKNATVKDTAEKGNTTIAPGLDKNTIVKDIVVK
>NZ_CP045224.1|WP_003424164.1|1077123_1077381_+|hypothetical-protein
MVKCTKLIGGVITMKKNILGVLLPLLTMIIIFVLSFENIITNSLGLSDMDIKGILISGVVLYIPVSFLVNGIICAKKQIKWKISK
>NZ_CP045224.1|WP_003424163.1|1077703_1077988_+|hypothetical-protein
MTFEVEFYTFEGINMEAEMYVQVAMMASKVVKITGVDEVIKKLVKKFLNNKVEEALGKQRSKKELKLIENNFNEYMERSYKNYIYMNTIVFRNQ
>NZ_CP045224.1|WP_003424162.1|1078264_1078501_-|hypothetical-protein
MAPNFNVENIVLEDKEIVSTPQKYVLISRYYDNGKTIAFIEMNSTKYKTEYIRNFDQYVDEFSTLEETEECLQECLSA

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Crispr_ID: NZ_CP045224_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045224_8

1793062-1795725

TypeI-B

III-B

Consensus_repeat	Method
NGTTAAACAGTAACATGAGATGTATTTAAAT	CRT
GTTAAACAGTAACATGAGATGTATTTAAAT	CRISPRCasFinder
GTTAAACAGTAACATGAGATGTATTTAAAT	PILER-CR

40 spacers

cas3,cas5,cas7b,cas8b1,cas6,cas4,cas1,cas2

The CRISPR arrays of NZ_CP045224_8

>merge|NZ_CP045224|8|1793062-1795725|CRT,CRISPRCasFinder,PILER-CR
TGTATATTAGTGTTTTCAGTGTATTTAAGGGAATTATATTTTTAAGAAGTACTGATTTTAAAGTGGTTAAACAGTAACATGAGATGTATTTAAATATGTTTAAGTCAGATGGCTCACCAAATCAAATGTTTGTTAAACAGTAACATGAGATGTATTTAAATTTTATTGTAGCTGTTATAACTTCTTTATTTGTATTAGTTAAACAGTAACATGAGATGTATTTAAATTGATTTATTAGAGGAAAATAGAGAATTAAATATTAAGTTAAACAGTAACATGAGATGTATTTAAATTATTGCTCTAAATTTAGTAGACCAAGTTCAATTTCTGTTAAACAGTAACATGAGATGTATTTAAATTTAAATGCTTTATAAAGTATTAATTCATTTTGTAACGTTAAACAGTAACATGAGATGTATTTAAATTATTAATCCTTCTATTGGAAAATATCGTCTTCAAGAGTTAAACAGTAACATGAGATGTATTTAAATTATAGTTTTGTAGCTCTTTCAAGTTCATCTGCATTTGTTAAACAGTAACATGAGATGTATTTAAATATATATCTAAATGGATTATTATATCTAACTCCATCTGTTAAACAGTAACATGAGATGTATTTAAATATTTTATAATGGTAAAAAAGAGTTTTACATAGCTGGTTAAACAGTAACATGAGATGTATTTAAATTTTTGAAGTTTAGTTATATCTGGGTCACCAGTCTGTGTTAAACAGTAACATGAGATGTATTTAAATCAGCATCTAAACCTTCTCTTCTTGCTTCCTCTGAAGTTAAACAGTAACATGAGATGTATTTAAATTTAAAATTCAATTTAGTAAATGAAGTTAATTCTGGAGTTAAACAGTAACATGAGATGTATTTAAATTTTTCTTTTGCAGCACTTCCTAGAACATCTCCATCAGTTAAACAGTAACATGAGATGTATTTAAATTCAAATCTAACTGATGTTCTTTTATTATCAAAAGGTTAAACAGTAACATGAGATGTATTTAAATTCTTTAGCTTTTTCTATTTCAGCAATTATCTCTACTGTTAAACAGTAACATGAGATGTATTTAAATGGATTATCCAATCTTTAATCTTATTACCATACCATTGTTAAACAGTAACATGAGATGTATTTAAATTATCTCTTAAAGCACTATCTAATTCAACAATAGTTGGTTAAACAGTAACATGAGATGTATTTAAATTATTGAACTTAGCATCTAATTTAGTATTTTTAGTAGGTTAAACAGTAACATGAGATGTATTTAAATTAGAATAAAAATTACTTGCAGAATAAAAAATGTCTTCGTTAAACAGTAACATGAGATGTATTTAAATTAGAAAAAAGTGTACATTGACAACTGAATATCCCCTGTTAAACAGTAACATGAGATGTATTTAAATACACTTATTTTGATTTTATTTATTTTAATTTTTTATGTTAAACAGTAACATGAGATGTATTTAAATTCCATCTACTTTTTTACTTTTAGCTTTTTCTTTAGTGTTAAACAGTAACATGAGATGTATTTAAATAGTCTGAAGATGAGCGAATGTGCTATATCTGTAATAGTTAAACAGTAACATGAGATGTATTTAAATTTAAATATAATAAATCGTAATGTACAAAAATAACTTAGTTAAACAGTAACATGAGATGTATTTAAATTTTCTTGAGTTAATTGAACCCCCATTTTTAAGCTCCGTTAAACAGTAACATGAGATGTATTTAAATTTTTCTTCTAGCTCTTTTTTCTTAGCCATTTTACCAGTTAAACAGTAACATGAGATGTATTTAAATATGTTTATACATGAGTTTAGTGATAGGTTCTTGGTCGTTAAACAGTAACATGAGATGTATTTAAATAAGGCAAGTGATTTGCTATTTAGAATAGGTGTAAACGTTAAACAGTAACATGAGATGTATTTAAATATTTCTTTTTGTGAAGTGTTAAGAGATTGCTCTTCGTTAAACAGTAACATGAGATGTATTTAAATACAGTAGCTATTCCAATTTCTTCTGCTTGTGGCATAGTTAAACAGTAACATGAGATGTATTTAAATTCAAAGATGCCCCTCTAGCTGGTTTTTGGGTATCTAGTTAAACAGTAACATGAGATGTATTTAAATTGTGTTGAGTCGTGATATTGACTTTTTCGGAAACGGGTTAAACAGTAACATGAGATGTATTTAAATTTGTAGTCCTTCCATTTCCATCACACAAAAAGCATGTTAAACAGTAACATGAGATGTATTTAAATTCTATGTTATGTACATGATTACCTTGTTTGAGTAGGTTAAACAGTAACATGAGATGTATTTAAATTAAGAGTCTCTTTGTATATCAATTTCTCTAGTAGATGTTAAACAGTAACATGAGATGTATTTAAATTAAATTATTAGTTTTAAAATTTAAAGGGGGAAAAAAGTTAAACAGTAACATGAGATGTATTTAAATGCTAACTTAATTACTTGTTCCACATTTGCTAATACCGTTAAACAGTAACATGAGATGTATTTAAATAAATATTCAATATAGTTTTTAAATACACTTTCCATTGTTAAACAGTAACATGAGATGTATTTAAATTCATTAGTACTTGTTATTCCAGTAAAAGCTACTTTGGTTAAACAGTAACATAAGATGTATCTAAAT

>NZ_CP045224|8|5|1793062-1795725|CRT
TGTATATTAGTGTTTTCAGTGTATTTAAGG	GAATTATATTTTTAAGAAGTACTGATTTTAAAGTG
GTTAAACAGTAACATGAGATGTATTTAAAT	ATGTTTAAGTCAGATGGCTCACCAAATCAAATGTTT
GTTAAACAGTAACATGAGATGTATTTAAAT	TTTATTGTAGCTGTTATAACTTCTTTATTTGTATTA
GTTAAACAGTAACATGAGATGTATTTAAAT	TGATTTATTAGAGGAAAATAGAGAATTAAATATTAA
GTTAAACAGTAACATGAGATGTATTTAAAT	TATTGCTCTAAATTTAGTAGACCAAGTTCAATTTCT
GTTAAACAGTAACATGAGATGTATTTAAAT	TTAAATGCTTTATAAAGTATTAATTCATTTTGTAAC
GTTAAACAGTAACATGAGATGTATTTAAAT	TATTAATCCTTCTATTGGAAAATATCGTCTTCAAGA
GTTAAACAGTAACATGAGATGTATTTAAAT	TATAGTTTTGTAGCTCTTTCAAGTTCATCTGCATTT
GTTAAACAGTAACATGAGATGTATTTAAAT	ATATATCTAAATGGATTATTATATCTAACTCCATCT
GTTAAACAGTAACATGAGATGTATTTAAAT	ATTTTATAATGGTAAAAAAGAGTTTTACATAGCTG
GTTAAACAGTAACATGAGATGTATTTAAAT	TTTTGAAGTTTAGTTATATCTGGGTCACCAGTCTGT
GTTAAACAGTAACATGAGATGTATTTAAAT	CAGCATCTAAACCTTCTCTTCTTGCTTCCTCTGAA
GTTAAACAGTAACATGAGATGTATTTAAAT	TTAAAATTCAATTTAGTAAATGAAGTTAATTCTGGA
GTTAAACAGTAACATGAGATGTATTTAAAT	TTTTCTTTTGCAGCACTTCCTAGAACATCTCCATCA
GTTAAACAGTAACATGAGATGTATTTAAAT	TCAAATCTAACTGATGTTCTTTTATTATCAAAAG
GTTAAACAGTAACATGAGATGTATTTAAAT	TCTTTAGCTTTTTCTATTTCAGCAATTATCTCTACT
GTTAAACAGTAACATGAGATGTATTTAAAT	GGATTATCCAATCTTTAATCTTATTACCATACCATT
GTTAAACAGTAACATGAGATGTATTTAAAT	TATCTCTTAAAGCACTATCTAATTCAACAATAGTTG
GTTAAACAGTAACATGAGATGTATTTAAAT	TATTGAACTTAGCATCTAATTTAGTATTTTTAGTAG
GTTAAACAGTAACATGAGATGTATTTAAAT	TAGAATAAAAATTACTTGCAGAATAAAAAATGTCTTC
GTTAAACAGTAACATGAGATGTATTTAAAT	TAGAAAAAAGTGTACATTGACAACTGAATATCCCCT
GTTAAACAGTAACATGAGATGTATTTAAAT	ACACTTATTTTGATTTTATTTATTTTAATTTTTTAT
GTTAAACAGTAACATGAGATGTATTTAAAT	TCCATCTACTTTTTTACTTTTAGCTTTTTCTTTAGT
GTTAAACAGTAACATGAGATGTATTTAAAT	AGTCTGAAGATGAGCGAATGTGCTATATCTGTAATA
GTTAAACAGTAACATGAGATGTATTTAAAT	TTAAATATAATAAATCGTAATGTACAAAAATAACTTA
GTTAAACAGTAACATGAGATGTATTTAAAT	TTTCTTGAGTTAATTGAACCCCCATTTTTAAGCTCC
GTTAAACAGTAACATGAGATGTATTTAAAT	TTTTCTTCTAGCTCTTTTTTCTTAGCCATTTTACCA
GTTAAACAGTAACATGAGATGTATTTAAAT	ATGTTTATACATGAGTTTAGTGATAGGTTCTTGGTC
GTTAAACAGTAACATGAGATGTATTTAAAT	AAGGCAAGTGATTTGCTATTTAGAATAGGTGTAAAC
GTTAAACAGTAACATGAGATGTATTTAAAT	ATTTCTTTTTGTGAAGTGTTAAGAGATTGCTCTTC
GTTAAACAGTAACATGAGATGTATTTAAAT	ACAGTAGCTATTCCAATTTCTTCTGCTTGTGGCATA
GTTAAACAGTAACATGAGATGTATTTAAAT	TCAAAGATGCCCCTCTAGCTGGTTTTTGGGTATCTA
GTTAAACAGTAACATGAGATGTATTTAAAT	TGTGTTGAGTCGTGATATTGACTTTTTCGGAAACGG
GTTAAACAGTAACATGAGATGTATTTAAAT	TTGTAGTCCTTCCATTTCCATCACACAAAAAGCAT
GTTAAACAGTAACATGAGATGTATTTAAAT	TCTATGTTATGTACATGATTACCTTGTTTGAGTAG
GTTAAACAGTAACATGAGATGTATTTAAAT	TAAGAGTCTCTTTGTATATCAATTTCTCTAGTAGAT
GTTAAACAGTAACATGAGATGTATTTAAAT	TAAATTATTAGTTTTAAAATTTAAAGGGGGAAAAAA
GTTAAACAGTAACATGAGATGTATTTAAAT	GCTAACTTAATTACTTGTTCCACATTTGCTAATACC
GTTAAACAGTAACATGAGATGTATTTAAAT	AAATATTCAATATAGTTTTTAAATACACTTTCCATT
GTTAAACAGTAACATGAGATGTATTTAAAT	TCATTAGTACTTGTTATTCCAGTAAAAGCTACTTTG
GTTAAACAGTAACATAAGATGTATCTAAAT

>NZ_CP045224|8|6|1793127-1795725|CRISPRCasFinder
GTTAAACAGTAACATGAGATGTATTTAAAT	ATGTTTAAGTCAGATGGCTCACCAAATCAAATGTTT
GTTAAACAGTAACATGAGATGTATTTAAAT	TTTATTGTAGCTGTTATAACTTCTTTATTTGTATTA
GTTAAACAGTAACATGAGATGTATTTAAAT	TGATTTATTAGAGGAAAATAGAGAATTAAATATTAA
GTTAAACAGTAACATGAGATGTATTTAAAT	TATTGCTCTAAATTTAGTAGACCAAGTTCAATTTCT
GTTAAACAGTAACATGAGATGTATTTAAAT	TTAAATGCTTTATAAAGTATTAATTCATTTTGTAAC
GTTAAACAGTAACATGAGATGTATTTAAAT	TATTAATCCTTCTATTGGAAAATATCGTCTTCAAGA
GTTAAACAGTAACATGAGATGTATTTAAAT	TATAGTTTTGTAGCTCTTTCAAGTTCATCTGCATTT
GTTAAACAGTAACATGAGATGTATTTAAAT	ATATATCTAAATGGATTATTATATCTAACTCCATCT
GTTAAACAGTAACATGAGATGTATTTAAAT	ATTTTATAATGGTAAAAAAGAGTTTTACATAGCTG
GTTAAACAGTAACATGAGATGTATTTAAAT	TTTTGAAGTTTAGTTATATCTGGGTCACCAGTCTGT
GTTAAACAGTAACATGAGATGTATTTAAAT	CAGCATCTAAACCTTCTCTTCTTGCTTCCTCTGAA
GTTAAACAGTAACATGAGATGTATTTAAAT	TTAAAATTCAATTTAGTAAATGAAGTTAATTCTGGA
GTTAAACAGTAACATGAGATGTATTTAAAT	TTTTCTTTTGCAGCACTTCCTAGAACATCTCCATCA
GTTAAACAGTAACATGAGATGTATTTAAAT	TCAAATCTAACTGATGTTCTTTTATTATCAAAAG
GTTAAACAGTAACATGAGATGTATTTAAAT	TCTTTAGCTTTTTCTATTTCAGCAATTATCTCTACT
GTTAAACAGTAACATGAGATGTATTTAAAT	GGATTATCCAATCTTTAATCTTATTACCATACCATT
GTTAAACAGTAACATGAGATGTATTTAAAT	TATCTCTTAAAGCACTATCTAATTCAACAATAGTTG
GTTAAACAGTAACATGAGATGTATTTAAAT	TATTGAACTTAGCATCTAATTTAGTATTTTTAGTAG
GTTAAACAGTAACATGAGATGTATTTAAAT	TAGAATAAAAATTACTTGCAGAATAAAAAATGTCTTC
GTTAAACAGTAACATGAGATGTATTTAAAT	TAGAAAAAAGTGTACATTGACAACTGAATATCCCCT
GTTAAACAGTAACATGAGATGTATTTAAAT	ACACTTATTTTGATTTTATTTATTTTAATTTTTTAT
GTTAAACAGTAACATGAGATGTATTTAAAT	TCCATCTACTTTTTTACTTTTAGCTTTTTCTTTAGT
GTTAAACAGTAACATGAGATGTATTTAAAT	AGTCTGAAGATGAGCGAATGTGCTATATCTGTAATA
GTTAAACAGTAACATGAGATGTATTTAAAT	TTAAATATAATAAATCGTAATGTACAAAAATAACTTA
GTTAAACAGTAACATGAGATGTATTTAAAT	TTTCTTGAGTTAATTGAACCCCCATTTTTAAGCTCC
GTTAAACAGTAACATGAGATGTATTTAAAT	TTTTCTTCTAGCTCTTTTTTCTTAGCCATTTTACCA
GTTAAACAGTAACATGAGATGTATTTAAAT	ATGTTTATACATGAGTTTAGTGATAGGTTCTTGGTC
GTTAAACAGTAACATGAGATGTATTTAAAT	AAGGCAAGTGATTTGCTATTTAGAATAGGTGTAAAC
GTTAAACAGTAACATGAGATGTATTTAAAT	ATTTCTTTTTGTGAAGTGTTAAGAGATTGCTCTTC
GTTAAACAGTAACATGAGATGTATTTAAAT	ACAGTAGCTATTCCAATTTCTTCTGCTTGTGGCATA
GTTAAACAGTAACATGAGATGTATTTAAAT	TCAAAGATGCCCCTCTAGCTGGTTTTTGGGTATCTA
GTTAAACAGTAACATGAGATGTATTTAAAT	TGTGTTGAGTCGTGATATTGACTTTTTCGGAAACGG
GTTAAACAGTAACATGAGATGTATTTAAAT	TTGTAGTCCTTCCATTTCCATCACACAAAAAGCAT
GTTAAACAGTAACATGAGATGTATTTAAAT	TCTATGTTATGTACATGATTACCTTGTTTGAGTAG
GTTAAACAGTAACATGAGATGTATTTAAAT	TAAGAGTCTCTTTGTATATCAATTTCTCTAGTAGAT
GTTAAACAGTAACATGAGATGTATTTAAAT	TAAATTATTAGTTTTAAAATTTAAAGGGGGAAAAAA
GTTAAACAGTAACATGAGATGTATTTAAAT	GCTAACTTAATTACTTGTTCCACATTTGCTAATACC
GTTAAACAGTAACATGAGATGTATTTAAAT	AAATATTCAATATAGTTTTTAAATACACTTTCCATT
GTTAAACAGTAACATGAGATGTATTTAAAT	TCATTAGTACTTGTTATTCCAGTAAAAGCTACTTTG
GTTAAACAGTAACATAAGATGTATCTAAAT

>NZ_CP045224|8|3|1793325-1795659|PILER-CR
GTTAAACAGTAACATGAGATGTATTTAAAT	TATTGCTCTAAATTTAGTAGACCAAGTTCAATTTCT
GTTAAACAGTAACATGAGATGTATTTAAAT	TTAAATGCTTTATAAAGTATTAATTCATTTTGTAAC
GTTAAACAGTAACATGAGATGTATTTAAAT	TATTAATCCTTCTATTGGAAAATATCGTCTTCAAGA
GTTAAACAGTAACATGAGATGTATTTAAAT	TATAGTTTTGTAGCTCTTTCAAGTTCATCTGCATTT
GTTAAACAGTAACATGAGATGTATTTAAAT	ATATATCTAAATGGATTATTATATCTAACTCCATCT
GTTAAACAGTAACATGAGATGTATTTAAAT	ATTTTATAATGGTAAAAAAGAGTTTTACATAGCTG
GTTAAACAGTAACATGAGATGTATTTAAAT	TTTTGAAGTTTAGTTATATCTGGGTCACCAGTCTGT
GTTAAACAGTAACATGAGATGTATTTAAAT	CAGCATCTAAACCTTCTCTTCTTGCTTCCTCTGAA
GTTAAACAGTAACATGAGATGTATTTAAAT	TTAAAATTCAATTTAGTAAATGAAGTTAATTCTGGA
GTTAAACAGTAACATGAGATGTATTTAAAT	TTTTCTTTTGCAGCACTTCCTAGAACATCTCCATCA
GTTAAACAGTAACATGAGATGTATTTAAAT	TCAAATCTAACTGATGTTCTTTTATTATCAAAAG
GTTAAACAGTAACATGAGATGTATTTAAAT	TCTTTAGCTTTTTCTATTTCAGCAATTATCTCTACT
GTTAAACAGTAACATGAGATGTATTTAAAT	GGATTATCCAATCTTTAATCTTATTACCATACCATT
GTTAAACAGTAACATGAGATGTATTTAAAT	TATCTCTTAAAGCACTATCTAATTCAACAATAGTTG
GTTAAACAGTAACATGAGATGTATTTAAAT	TATTGAACTTAGCATCTAATTTAGTATTTTTAGTAG
GTTAAACAGTAACATGAGATGTATTTAAAT	TAGAATAAAAATTACTTGCAGAATAAAAAATGTCTTC
GTTAAACAGTAACATGAGATGTATTTAAAT	TAGAAAAAAGTGTACATTGACAACTGAATATCCCCT
GTTAAACAGTAACATGAGATGTATTTAAAT	ACACTTATTTTGATTTTATTTATTTTAATTTTTTAT
GTTAAACAGTAACATGAGATGTATTTAAAT	TCCATCTACTTTTTTACTTTTAGCTTTTTCTTTAGT
GTTAAACAGTAACATGAGATGTATTTAAAT	AGTCTGAAGATGAGCGAATGTGCTATATCTGTAATA
GTTAAACAGTAACATGAGATGTATTTAAAT	TTAAATATAATAAATCGTAATGTACAAAAATAACTTA
GTTAAACAGTAACATGAGATGTATTTAAAT	TTTCTTGAGTTAATTGAACCCCCATTTTTAAGCTCC
GTTAAACAGTAACATGAGATGTATTTAAAT	TTTTCTTCTAGCTCTTTTTTCTTAGCCATTTTACCA
GTTAAACAGTAACATGAGATGTATTTAAAT	ATGTTTATACATGAGTTTAGTGATAGGTTCTTGGTC
GTTAAACAGTAACATGAGATGTATTTAAAT	AAGGCAAGTGATTTGCTATTTAGAATAGGTGTAAAC
GTTAAACAGTAACATGAGATGTATTTAAAT	ATTTCTTTTTGTGAAGTGTTAAGAGATTGCTCTTC
GTTAAACAGTAACATGAGATGTATTTAAAT	ACAGTAGCTATTCCAATTTCTTCTGCTTGTGGCATA
GTTAAACAGTAACATGAGATGTATTTAAAT	TCAAAGATGCCCCTCTAGCTGGTTTTTGGGTATCTA
GTTAAACAGTAACATGAGATGTATTTAAAT	TGTGTTGAGTCGTGATATTGACTTTTTCGGAAACGG
GTTAAACAGTAACATGAGATGTATTTAAAT	TTGTAGTCCTTCCATTTCCATCACACAAAAAGCAT
GTTAAACAGTAACATGAGATGTATTTAAAT	TCTATGTTATGTACATGATTACCTTGTTTGAGTAG
GTTAAACAGTAACATGAGATGTATTTAAAT	TAAGAGTCTCTTTGTATATCAATTTCTCTAGTAGAT
GTTAAACAGTAACATGAGATGTATTTAAAT	TAAATTATTAGTTTTAAAATTTAAAGGGGGAAAAAA
GTTAAACAGTAACATGAGATGTATTTAAAT	GCTAACTTAATTACTTGTTCCACATTTGCTAATACC
GTTAAACAGTAACATGAGATGTATTTAAAT	AAATATTCAATATAGTTTTTAAATACACTTTCCATT
GTTAAACAGTAACATGAGATGTATTTAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045224.1\|WP_003424500.1\|1795809_1796304_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NZ_CP045224.1\|WP_003424487.1\|1805270_1805495_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_003424497.1\|1797547_1797838_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP045224.1\|WP_003424527.1\|1780675_1781455_+\|phosphatidate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|366491
NZ_CP045224.1\|WP_003424492.1\|1800061_1801066_+\|RIP-metalloprotease-RseP	unknown	unknown	gnl\|CDD\|308008
NZ_CP045224.1\|WP_003424502.1\|1790378_1792937_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|187770
NZ_CP045224.1\|WP_071585686.1\|1782216_1782315_+\|diguanylate-cyclase	unknown	unknown	gnl\|CDD\|143635
NZ_CP045224.1\|WP_003424519.1\|1782512_1784333_+\|bifunctional-diguanylate-cyclase/phosphodiesterase	unknown	unknown	gnl\|CDD\|238923
NZ_CP045224.1\|WP_003424488.1\|1803949_1805074_-\|DUF3810-domain-containing-protein	unknown	unknown	gnl\|CDD\|378933
NZ_CP045224.1\|WP_003424499.1\|1796338_1797337_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|187853
NZ_CP045224.1\|WP_003424515.1\|1784417_1784999_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_003424505.1\|1786870_1788631_+\|hypothetical-protein	cas8b1	mkCas0106_cas8b1_CAS-I-B	gnl\|CDD\|188234
NZ_CP045224.1\|WP_003424494.1\|1798894_1800049_+\|1-deoxy-D-xylulose-5-phosphate-reductoisomerase	unknown	unknown	gnl\|CDD\|235472
NZ_CP045224.1\|WP_003424503.1\|1789614_1790355_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NZ_CP045224.1\|WP_009890274.1\|1798527_1798731_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|226181
NZ_CP045224.1\|WP_003424522.1\|1781983_1782127_+\|diguanylate-cyclase	unknown	unknown	gnl\|CDD\|143635
NZ_CP045224.1\|WP_003424506.1\|1786184_1786880_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl\|CDD\|273848
NZ_CP045224.1\|WP_003424490.1\|1801248_1802304_+\|flavodoxin-dependent-(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate-synthase	unknown	unknown	gnl\|CDD\|377382
NZ_CP045224.1\|WP_003424489.1\|1802651_1803476_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_032510215.1\|1788623_1789613_+\|type-I-CRISPR-associated-protein-Cas7	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl\|CDD\|377458

Protein	Function_ID	Function_description	E-value
NZ_CP045224.1\|WP_003424500.1\|1795809_1796304_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	9.71529e-51
NZ_CP045224.1\|WP_003424497.1\|1797547_1797838_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.32926e-26
NZ_CP045224.1\|WP_003424527.1\|1780675_1781455_+\|phosphatidate-cytidylyltransferase	gnl\|CDD\|366491	pfam01148, CTP_transf_1, Cytidylyltransferase family. The members of this family are integral membrane protein cytidylyltransferases. The family includes phosphatidate cytidylyltransferase EC:2.7.7.41 as well as Sec59 from yeast. Sec59 is a dolichol kinase EC:2.7.1.108.	1.80505e-48
NZ_CP045224.1\|WP_003424492.1\|1800061_1801066_+\|RIP-metalloprotease-RseP	gnl\|CDD\|308008	pfam02163, Peptidase_M50, Peptidase family M50.	1.00896e-72
NZ_CP045224.1\|WP_003424502.1\|1790378_1792937_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|187770	cd09639, Cas3_I, CRISPR/Cas system-associated protein Cas3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; DEAD/DEAH box helicase DNA helicase cas3'; Often but not always is fused to HD nuclease domain; signature gene for Type I.	1.91612e-33
NZ_CP045224.1\|WP_071585686.1\|1782216_1782315_+\|diguanylate-cyclase	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	1.47328e-07
NZ_CP045224.1\|WP_003424519.1\|1782512_1784333_+\|bifunctional-diguanylate-cyclase/phosphodiesterase	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	3.28674e-84
NZ_CP045224.1\|WP_003424488.1\|1803949_1805074_-\|DUF3810-domain-containing-protein	gnl\|CDD\|378933	pfam12725, DUF3810, Protein of unknown function (DUF3810). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 333 and 377 amino acids in length. There is a conserved HEXXH sequence motif that is characteristic of metallopeptidases. This family may therefore belong to an as yet uncharacterized family of peptidase enzymes.	4.41063e-125
NZ_CP045224.1\|WP_003424499.1\|1796338_1797337_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187853	cd09722, Cas1_I-B, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	2.60063e-138
NZ_CP045224.1\|WP_003424505.1\|1786870_1788631_+\|hypothetical-protein	gnl\|CDD\|188234	TIGR02591, cas_Csh1, CRISPR-associated protein Cas8b/Csh1, subtype I-B/HMARI. This domain is found in the C-terminal 2/3 of a family of CRISPR associated proteins of the Hmari subtype. Except for the two sequences from halophilic archaea this domain contains a pair of CXXC motifs.	9.50984e-15
NZ_CP045224.1\|WP_003424494.1\|1798894_1800049_+\|1-deoxy-D-xylulose-5-phosphate-reductoisomerase	gnl\|CDD\|235472	PRK05447, PRK05447, 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional.	0
NZ_CP045224.1\|WP_003424503.1\|1789614_1790355_+\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	8.69345e-53
NZ_CP045224.1\|WP_009890274.1\|1798527_1798731_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|226181	COG3655, COG3655, Predicted transcriptional regulator [Transcription].	5.3259e-13
NZ_CP045224.1\|WP_003424522.1\|1781983_1782127_+\|diguanylate-cyclase	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	2.95513e-16
NZ_CP045224.1\|WP_003424506.1\|1786184_1786880_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	3.07743e-18
NZ_CP045224.1\|WP_003424490.1\|1801248_1802304_+\|flavodoxin-dependent-(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate-synthase	gnl\|CDD\|377382	pfam04551, GcpE, GcpE protein. In a variety of organisms, including plants and several eubacteria, isoprenoids are synthesized by the mevalonate-independent 2-C-methyl-D-erythritol 4-phosphate (MEP) pathway. Although different enzymes of this pathway have been described, the terminal biosynthetic steps of the MEP pathway have not been fully elucidated. GcpE gene of Escherichia coli is involved in this pathway.	0
NZ_CP045224.1\|WP_032510215.1\|1788623_1789613_+\|type-I-CRISPR-associated-protein-Cas7	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	1.0311e-49

>NZ_CP045224.1|WP_003424502.1|1790378_1792937_+|CRISPR-associated-helicase/endonuclease-Cas3
MYFKKVELFDISNNINNCKNIYAHINKDRKPETLKEHSDLSYSYLMKLCVKKDLSSCLERIENKFFKKDSFLSKNFYREIILNMVYMHDIGKINSSFQFVKMQNKNFKKISLRYTKHSFISSMLYFDYYFEKLKKYDFEEKKILSLFLMINTYTISKHHGVLKSFKEFLFLFKDEFINIKENFKDLFKNNYNLELKSVPKTIEKMVRGVEGYLDDSHIKDNLAIDLYIYSKLMFSIVTSCDFYATSEYNSGNSIDGFGTIDNYNKYYDVLKKSEIYKGMKKYREYLNNNSECPYKENDINRLRTEMSIEAEDAITHNTRKRIFYLEAPTGSGKTVTSINLALKSIELNQSLKKIFYIFPFNTLVEQTKDVFINEIFNSVKDIQKDVVVINSITPIQTEDKEEDNKNVEYCVTKQEIDYDKSLLNRQFLHYPIVLTTNIGFFNYLFGVSREECFPLIHMINSVIILDEIQNYKNEIWKEIILFLEKYADILNIKFIIMSATLPRLNKLGCNDDNFAYLVKNREKFFKNHLFKDRVNISFEMLNSEINDIEEISEKVIEEAEIYNKILIEFIKKSSALEFYKNIKEKLKYKLEDVFLLTGDDNKLERKKIINKIKDMNSVILVATQVVEAGVDIDMDLGFKDISTIDSDEQFLGRINRSCKKLNSKVYFFNLDDASKIYKKDVRKERHLTLNEESNRKIILDKDFEKYYDKIIARIEENKHKHNDKNIEVFIKDIVGNLNFTEVKKWMALIPDLKEYTIFLNTIVKDESGNMIVGSDVWYEYISLLKNDNVEYSEKRVKMSEIMEKLDYFTYKVQKFDNSFNDLVGDIFYIDDGSKYFTEGKFDRSKFNQNEFL
>NZ_CP045224.1|WP_003424503.1|1789614_1790355_+|type-I-B-CRISPR-associated-protein-Cas5
MEVLKFNLSGKTAFFKKPDVNSIIYFTYGNIHKIALMGILGACLGLGGYNQQSKEDEYPEFYSLLKDIKMSIVPKHEFGYINKKVHIFNNSVGYASKEEGGNLIIKEQWLENVSWDIYIQLEDSTTSRELKRRFLSNKFVYIPYLGKNDHIANISEIEIITDFYKTEDINRVDSFFIREDFEFEKSYFDDNDDYEEPFKYQEKLPYRLHRMTNQYILETIIFTNMSVKLINKKEVYQVKGLNLIFI
>NZ_CP045224.1|WP_032510215.1|1788623_1789613_+|type-I-CRISPR-associated-protein-Cas7
MNRRVYGVLGIKSIMSNWNADFSGYPKTTSTGEVFGSDKALKFPMKKMWENEGEKVLYVKSLKIDESKKGEIKIRPKSLKERYEELFDIEELKLEKNQQKVLENLFKAIDVKNFGATFAEEGNNIGIMGAVQIGQGFNKYEDINVEEQQILSPFRDPRAKDKKKSTNEEEKEDANSTTLGKKIVSDEAHYFYPFSINPKAYEVFVNMGVTDGYTKNDYKKFKEAALVSATAFNTNSKLGCENEFALFVETDEELYLPDLAQYITFEKREKSKDLICINIIHLIAELKDDIKSVEIYYNPYKIEIKPFKDEILPKIDKVKFMNIFTRKEV
>NZ_CP045224.1|WP_003424505.1|1786870_1788631_+|hypothetical-protein
MVIGGENLLKDCLEIFEKEYKSLGNRLITDSYVLSYGTYILVKNFSNIDILEVSKNNVDSTEDIYHKFCELDYLSKLVSIDKSVDSKKIIHSNNYLSFFVKKENLRPDKNNNVKLTEEIIDNYYDALLNPRIKYKSDKRKKEIYDSIENKYGKVDENKLNKIRLWIKTNIFDLVESVKKDKNYLKIFFDEKIELYNDENQKYLYPNIYNKNDFNVIIDGKNYGLPNDNMQLNEKKPFLKLKTRIRNSTPYLISDDEVLLQKAFFDYLMNKAANGEEVVYISSEKGIHRKTDIPNEFSGYILRIKKGKELEIHDFDTVVNLNTKIKRINVECIIPIEYERHNLKPNLEIGYINNLIKLEKTIDTIFFNKFMCNSYFKEIKNINLSDLVLRDILIRHREGLYTWFYKGRDNIVKQTFSNYSMGIIENSIKNNNYIRAKEQYNLRIAIINYFHGGSNMADKIKVISESLFEKINSIKTKCIQSDEEYYFAVGQLASYFISKNKSKNKNHSLINPILNAQNRKKIMLEIEKLFKKYNYDISYDNNRRFKNLYSMIVGYEVEEKKVNRDLLIGGYLYYSLIYTKSEENENE
>NZ_CP045224.1|WP_003424506.1|1786184_1786880_+|CRISPR-associated-endoribonuclease-Cas6
MIKCLEMSVKVYLLENISLDNTSKEIRKLIDDTLIIEEKYKEFHNKAGFKNYSFNLLYPLEKDKVYKKDCIYTFIIRTVDSELGMYFMNNLKNQYSDKIKVITMSKKVIPKKHIESIYSVTPIIAKFEDGYWRSNKTVEDLEKRIRENLIKKYNEFTNSKIDEDFELFQVIKFINRKPISTKYKNISLLGDKISFKVSENDMAQEIANFALGVGVGEINSRGFGFVNYRWL
>NZ_CP045224.1|WP_003424515.1|1784417_1784999_-|hypothetical-protein
MSYLLKINQFERSYDIGIFKNEQSIHKFIEKIPFVKKDSSNFNYTNYYMEFEDIPEYYEVNFNNYLYIITKFSFIPDGTEIFFTWDEIHCWDEKVATDKTFINGETLVDSYSFPNNEVKNYIQKRESLYRETKKYYKEKGLKIKRHALGSEDGEYVELVDDSILYLLDVHAVEIWEQSKNIEEFLYKYKKYFE
>NZ_CP045224.1|WP_003424519.1|1782512_1784333_+|bifunctional-diguanylate-cyclase/phosphodiesterase
MKKKYDFLIYAAIWLVAIIIFIFSLYHSIEHIKIINYTGIISSETQKVTKQELNNKRNDKLISQLDSILIELRTGNGKHRLQRCDNKEFQEKLIEMDAMWDSMKKEIRKVRNGGSGDKLYKLSEKYSSLSNQVVFISEKHSDIKLHFFATVLFIYLIISTISLLIWEYYNKRKFDKIFYTDNLTKIKNQVAFENRAIEILSHAYNKEYVLLNIDIDNFKYINDTHGYEYGDKVLVIVANVLAKTFNTKETCARVGSDNFVILAKYRESLLYEISKTLTDAIISELNMNVTQTISFCIGAYLVEIEKSNYKYINSIMDKANIAHKVSKMRGISSTVWYNENLLKQLQMENSIYNHMYKALENEEFQMYLQPKFQISSLNVVSAEALVRWFSPELGFLSPDQFIPLFEKSGFIIELDFYMLKKACSFIKKTFMKKNKYTYPIAVNFSRVTIYQNDFYQRFLDTVREYEIPFKYIEIEVTESAFNEISEPVISILDKLEKLGFLISMDDFGSGYSSLSLLCSLSINGLKLDKSLLKEKFNRAKVYSIIKCIIEMSHSIDMSIVCEGIETKKDLEFLKTVKCDLGQGFYFSKPIEEKEFFNKYVMDKQYN
>NZ_CP045224.1|WP_071585686.1|1782216_1782315_+|diguanylate-cyclase
MSVSIGISLYSKYGEQFYKLYRHADSALYRVK
>NZ_CP045224.1|WP_003424522.1|1781983_1782127_+|diguanylate-cyclase
MYNFKYVKDSMGYVFGDKILIDLAECLKRYFRETDTVGRVGGDEFII
>NZ_CP045224.1|WP_003424527.1|1780675_1781455_+|phosphatidate-cytidylyltransferase
MLTRIIASLALVPLFLFVVYGGIPLYIAETAIVYIALHEFYKAFKIKDVNPIFIIGYLFSIYLAVKNIFNLPLEYTYAVIFILFLASIIYMLMGKNNVIDVSITFLGVFYIGVFLDFIIITINEFEKGSIYVWLIFVISFMTDIFAYFSGYLLGKHKLIPKVSPKKTIEGAIGGIIGSTLCCILFGYLFGIDLLQLAIIGSIGSVIAQLGDLFASSIKRYVGIKDYGKIIPGHGGILDRFDSVILVAPFVYSAIKFFIR
>NZ_CP045224.1|WP_003424500.1|1795809_1796304_+|CRISPR-associated-protein-Cas4
MKITGTLINYYFHCKRQCWLLGNRINLEENSEDVKIGRLLHELKEEKSKYKEIAIENIKIDKLTREYLVEVKKSDADIEAVKWQVLLYLKKLKEKGIVRKGKIEFIEKNKTNKKIVFVDLSEVSEEQLISIEREIVNLINSDKAPCPDLKKGCKKCAYYEYCYI
>NZ_CP045224.1|WP_003424499.1|1796338_1797337_+|type-I-B-CRISPR-associated-endonuclease-Cas1
MGKTKYITSMGELTRKDNSICFRKNGRNVYIPVENTSEIFCLNEVSLNSKLLDFLSRANIVVHFFNYYGGYSGTFYPKEYLISGKVTVAQVKTFEDRREEIAKSIVNGIRINAINTLSHYYKHGNSEIQPLLSHLKKDSINKLEKSNNIKEILSVEGDIWQTFYTSFKYILREEFIFNKRVKRPPDNPLNAMISFGNSILYSKTVTAIYNTHLNQSVSFLHEPSESRFSLSLDLSENFKHVITFKTIFDLVNNRKINIEKHFDKNLNYCVLNDEGKQIFINSLEERLESVKEHPKLKRKVSLKTCIKLDAYKMLKCIMEEKSFIPYNIKDGL
>NZ_CP045224.1|WP_003424497.1|1797547_1797838_+|CRISPR-associated-endonuclease-Cas2
MKKKNNLNYNYVFVVYDVGEKRVSKVFKVCKKYLSHFQKSVFRGEITPSKIMSLKRDLENIIDKDNDFVCIIKLMNSNTFEEEILGNNSNCENMIL
>NZ_CP045224.1|WP_009890274.1|1798527_1798731_+|helix-turn-helix-domain-containing-protein
MISYAPLWKLLIDRKIKKMEFVNISGISISVLGRLGNDKSVSMDTMEKICLALDCKIEDVVEIKKGI
>NZ_CP045224.1|WP_003424494.1|1798894_1800049_+|1-deoxy-D-xylulose-5-phosphate-reductoisomerase
MKKISILGSTGSIGKQTLDVVREHRDKFEIVAISANSNIELLLEQIVEFKPKYVTVFEENKALKLKEMLPKNIEIEVLAGMEGLKIISSLDEVDVLLTAVVGMIGLVPTLCAIKKGIDIALANKETLVTAGELVMKEAEKYNVNILPVDSEHSAIFQCLNGENKKNIEKIILTASGGPFRGKKKGELVNITKNEALKHPNWSMGRKISIDSSTLMNKGLEVIEARWLFGVEQENIDVVVHPQSIIHSMVQYADSSIIAQLGCPDMRLPIQYALTYPDRMESSFERMNFSKFSTLTFEEPDLETFPCLKLAYECLKMGGTYSSVLNSANEVLVSEFLEDKIGFYDIPYYIEKTLEVHSSISEPTLEEILETDRWSRAYVANLIKK
>NZ_CP045224.1|WP_003424492.1|1800061_1801066_+|RIP-metalloprotease-RseP
MTIIAALILFSIIVLIHELGHFIFAKRSGIKVNEFSIGMGPKIYSVKKDTEYSIRALPIGGYVSMEGEDEEQISPNSFGNKSILQRFSTIVAGPIFNIILAAILLVPVFLYIGSPTTKLGKIMPDTPAQAVGLQVGDKINKINGNSVKTWDEVANIINTSSGGELKLSITRDGSDKVVNVTPKNNNGKYEIGIQPQREKDFWGSIVNACKTTVDMTKQMLTFLGQMITGRVPGGIGNAVAGPVGVIGMVSDAARTGIINVVYLAAVISLNLGIVNLLPIPALDGWRILMLLLEAVRGGKKLDPNKEGMINVVGFGALMLFMLFITYKDILRLFQ
>NZ_CP045224.1|WP_003424490.1|1801248_1802304_+|flavodoxin-dependent-(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate-synthase
MSYERRKTREVSVGTVKIGGENPISIQSMTNTDTRDADATIAQIKRLEEAGCDIVRVAVPDIKAAKNIAKIKSSVNIPIIADIHFDYKLALEAIEQGVDGIRINPGNIGSIERVKMVVEKCKERNLKIRIGVNGGSLEKELLKKYGSATAEALVESAMGHIKILEDLDFHNIVISLKSSDIYKTVDAYELISKKVDYPLHIGITESGSVHKGTIKSSIGVGALLLKGIGDTVRISLTGDPVEEVIVGKQILRSLGLLNDKIKVISCPTCGRCNIDLISVVNEVEEKIGSMEKNITVAIMGCAVNGPGEAREADIGIAGGKGEGLLFKKGEIVRMIDGNKLVDELLEEIEKL
>NZ_CP045224.1|WP_003424489.1|1802651_1803476_+|hypothetical-protein
MRYKKISSLPILVVALLITGTTTTFSLSTTNSEKTSVYLASTVSTITKKVSDIQSSKGLVYNENIPLFINNSKIQYDDTPYHWPSNVISLTNSSEKAIMDYEITCLAYDKNGKPLELYWDAQNVAADGEVGSVGFSPAGVDYGIVTGISPVSPKSYSHTYRKMQQSPPQDIISMFEKQQGKAWVENWLKEWKQMEKEYAKQNAIAPGKNQNDAFLLFDKWKQSTGEHGVKYIISCVKQVTFNDGSVWKNSAYENWLKSFQGKEVSNSVLENYYK
>NZ_CP045224.1|WP_003424488.1|1803949_1805074_-|DUF3810-domain-containing-protein
MSKKTKYFSLILFPIALLLNFIASKVPNIVEKYYSQFIDKIIVQVLSKVSGIFPFSLYEITMYIIVISIFLFLCCTLSTIFNKKKKLNIFLKNSILNILSIVSIVYFLFVVLWGINYNRIPLETTLINNYNLENNTSIQSKQHSVKELTKLYKFLIIKANETRKLTLQDKNGIVKSNTDYNGVINRAQLGYDNILDILPSVSGSYSKPKYIISSNLMCYTGITGIYFPFTGEANVNIAIPDLYIPCTVEHEMAHQRGFASEDEANFIAYLTSIKHPNIDFNYSGYILALNYTASALSKVDYNAYVDISAGISDSVRRDLKNESKFWQKYEGKIDEISNEFNNSYLKANGVTEGTQSYGKMVDLLLTYYELYPYN
>NZ_CP045224.1|WP_003424487.1|1805270_1805495_+|hypothetical-protein
MIIKLTKDDFNFRFKQYEGMFFHAEIIESMESIRYKITKDKEGTELKEFGSTHIKDNMIYVPQIEAYIDLKSIK

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Crispr_ID: NZ_CP045224_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045224_9

1905827-1906793

Orphan

I-A

Consensus_repeat	Method
GTTTTATATTAACTAAGTGGTATGTAAA	PILER-CR
GTTTTATATTAACTAAGTGGTATGTAAAT	CRISPRCasFinder
NNNNNNGTTTTATATTAACTAAGTGGTATGTAAAT	CRT

14 spacers

The CRISPR arrays of NZ_CP045224_9

>merge|NZ_CP045224|9|1905827-1906793|PILER-CR,CRISPRCasFinder,CRT
GTTTTATATTAACTAAGTGGTATGTAAATTTAAGCTTAAAGATTATGGTTTTCAAGTTTTAGTTAAGTTTTATATTAACTAAGTGGTATGTAAATTTAAGAAATGCAGATAATAGGATACCTTTCAACTGGGTTTTATATTAACTAAGTGGTATGTAAATTGGAAACTAATATTTATATAAAACTTGTAAATATACAGGTTTTATATTAACTAAGTGGTATGTAAATCGAGAAATTGAGCTAATTTTACTATTATCAGCATTGTTTTATATTAACTAAGTGGTATGTAAATAAAGGTGTGAAAAGAGATGAGTTAAATCAAAGTGAAGTTTTATATTAACTAAGTGGTATGTAAATGAAACGAAGCTAGTTATTGTGATTATACAAGTTTCCGTTTTATATTAACTAAGTGGTATGTAAATTTAATAGCACATCTTCGCTTTCAAGTTTCTCTATCAGTTTTATATTAACTAAGTGGTATGTAAATTATATATTGGATGTCAATGTCAAGAATACAAAATTTAGTTTTATATTAACTAAGTGGTATGTAAATATAGGAAAATAGAGATAGGTTCACAATCTAATGATAGGTTTTATATTAACTAAGTGGTATGTAAATATTTTTTCTTTTAGTTTTTTAGGAACTGGTAATCCACAGTTTTATATTAACTAAGTGGTATGTAAATTTCTGAATCATATGAAAACAAAATCTTATTTGTATTGTTTTATATTAACTAAGTGGTATGTAAGTGAAATTATTAATGTTATTTCTACTCTTGCAGTTGCGTTTTATATTAACTAAGTGGTATATAAAGCATAGTCTATTGAACATTTATTAAGAGATAACTTTCGTTTTATATAGTTTTATATTAGCTATATTGAATTTAAATGTTTCACTATTGGACAACGGAAGTTTTTTCAGTGAGTAAAGATTGAATCACTTTATATTTATCTTAATTATGTGATAA

>NZ_CP045224|9|4|1905827-1906639|PILER-CR
GTTTTATATTAACTAAGTGGTATGTAAA	TTTAAGCTTAAAGATTATGGTTTTCAAGTTTTAGTTAA
GTTTTATATTAACTAAGTGGTATGTAAA	TTTAAGAAATGCAGATAATAGGATACCTTTCAACTGG
GTTTTATATTAACTAAGTGGTATGTAAA	TTGGAAACTAATATTTATATAAAACTTGTAAATATACAG
GTTTTATATTAACTAAGTGGTATGTAAA	TCGAGAAATTGAGCTAATTTTACTATTATCAGCATT
GTTTTATATTAACTAAGTGGTATGTAAA	TAAAGGTGTGAAAAGAGATGAGTTAAATCAAAGTGAA
GTTTTATATTAACTAAGTGGTATGTAAA	TGAAACGAAGCTAGTTATTGTGATTATACAAGTTTCC
GTTTTATATTAACTAAGTGGTATGTAAA	TTTAATAGCACATCTTCGCTTTCAAGTTTCTCTATCA
GTTTTATATTAACTAAGTGGTATGTAAA	TTATATATTGGATGTCAATGTCAAGAATACAAAATTTA
GTTTTATATTAACTAAGTGGTATGTAAA	TATAGGAAAATAGAGATAGGTTCACAATCTAATGATAG
GTTTTATATTAACTAAGTGGTATGTAAA	TATTTTTTCTTTTAGTTTTTTAGGAACTGGTAATCCACA
GTTTTATATTAACTAAGTGGTATGTAAA	TTTCTGAATCATATGAAAACAAAATCTTATTTGTATT
GTTTTATATTAACTAAGTGGTATGTAAG	TGAAATTATTAATGTTATTTCTACTCTTGCAGTTGC
GTTTTATATTAACTAAGTGGTATATAAA

>NZ_CP045224|9|7|1905827-1906715|CRISPRCasFinder
GTTTTATATTAACTAAGTGGTATGTAAAT	TTAAGCTTAAAGATTATGGTTTTCAAGTTTTAGTTAA
GTTTTATATTAACTAAGTGGTATGTAAAT	TTAAGAAATGCAGATAATAGGATACCTTTCAACTGG
GTTTTATATTAACTAAGTGGTATGTAAAT	TGGAAACTAATATTTATATAAAACTTGTAAATATACAG
GTTTTATATTAACTAAGTGGTATGTAAAT	CGAGAAATTGAGCTAATTTTACTATTATCAGCATT
GTTTTATATTAACTAAGTGGTATGTAAAT	AAAGGTGTGAAAAGAGATGAGTTAAATCAAAGTGAA
GTTTTATATTAACTAAGTGGTATGTAAAT	GAAACGAAGCTAGTTATTGTGATTATACAAGTTTCC
GTTTTATATTAACTAAGTGGTATGTAAAT	TTAATAGCACATCTTCGCTTTCAAGTTTCTCTATCA
GTTTTATATTAACTAAGTGGTATGTAAAT	TATATATTGGATGTCAATGTCAAGAATACAAAATTTA
GTTTTATATTAACTAAGTGGTATGTAAAT	ATAGGAAAATAGAGATAGGTTCACAATCTAATGATAG
GTTTTATATTAACTAAGTGGTATGTAAAT	ATTTTTTCTTTTAGTTTTTTAGGAACTGGTAATCCACA
GTTTTATATTAACTAAGTGGTATGTAAAT	TTCTGAATCATATGAAAACAAAATCTTATTTGTATT
GTTTTATATTAACTAAGTGGTATGTAAGT	GAAATTATTAATGTTATTTCTACTCTTGCAGTTGC
GTTTTATATTAACTAAGTGGTATATAAAG	CATAGTCTATTGAACATTTATTAAGAGATAACTTTCGTTTTATATA
GTTTTATATTAGCTATATTGAATTTAAAT

>NZ_CP045224|9|6|1905827-1906793|CRT
GTTTTATATTAACTAAGTGGTATGTAAAT	TTAAGCTTAAAGATTATGGTTTTCAAGTTTTAGTTAA
GTTTTATATTAACTAAGTGGTATGTAAAT	TTAAGAAATGCAGATAATAGGATACCTTTCAACTGG
GTTTTATATTAACTAAGTGGTATGTAAAT	TGGAAACTAATATTTATATAAAACTTGTAAATATACAG
GTTTTATATTAACTAAGTGGTATGTAAAT	CGAGAAATTGAGCTAATTTTACTATTATCAGCATT
GTTTTATATTAACTAAGTGGTATGTAAAT	AAAGGTGTGAAAAGAGATGAGTTAAATCAAAGTGAA
GTTTTATATTAACTAAGTGGTATGTAAAT	GAAACGAAGCTAGTTATTGTGATTATACAAGTTTCC
GTTTTATATTAACTAAGTGGTATGTAAAT	TTAATAGCACATCTTCGCTTTCAAGTTTCTCTATCA
GTTTTATATTAACTAAGTGGTATGTAAAT	TATATATTGGATGTCAATGTCAAGAATACAAAATTTA
GTTTTATATTAACTAAGTGGTATGTAAAT	ATAGGAAAATAGAGATAGGTTCACAATCTAATGATAG
GTTTTATATTAACTAAGTGGTATGTAAAT	ATTTTTTCTTTTAGTTTTTTAGGAACTGGTAATCCACA
GTTTTATATTAACTAAGTGGTATGTAAAT	TTCTGAATCATATGAAAACAAAATCTTATTTGTATT
GTTTTATATTAACTAAGTGGTATGTAAGT	GAAATTATTAATGTTATTTCTACTCTTGCAGTTGC
GTTTTATATTAACTAAGTGGTATATAAAG	CATAGTCTATTGAACATTTATTAAGAGATAACTTTCGTTTTATATA
GTTTTATATTAGCTATATTGAATTTAAAT	GTTTCACTATTGGACAACGGAAGTTTTTTCAGTGAGTAAAGATTGAATC
ACTTTATATTTATCTTAATTATGTGATAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045224.1\|WP_003424249.1\|1914723_1915758_+\|N-acetyl-gamma-glutamyl-phosphate-reductase	unknown	unknown	gnl\|CDD\|234761
NZ_CP045224.1\|WP_003424292.1\|1894921_1896622_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_003424265.1\|1909165_1909633_-\|DUF2975-domain-containing-protein	unknown	unknown	gnl\|CDD\|378586
NZ_CP045224.1\|WP_003424267.1\|1908939_1909155_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|226181
NZ_CP045224.1\|WP_003424287.1\|1897769_1898963_+\|aspartate-kinase	unknown	unknown	gnl\|CDD\|235843
NZ_CP045224.1\|WP_003424252.1\|1913278_1914046_+\|YoaP-domain-containing-protein	unknown	unknown	gnl\|CDD\|379530
NZ_CP045224.1\|WP_009905700.1\|1907430_1907715_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_003424254.1\|1912512_1912986_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379326
NZ_CP045224.1\|WP_003424281.1\|1901297_1902383_-\|AI-2E-family-transporter	unknown	unknown	gnl\|CDD\|223701
NZ_CP045224.1\|WP_003424272.1\|1905343_1905529_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|271189
NZ_CP045224.1\|WP_003424258.1\|1910618_1911317_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|274612
NZ_CP045224.1\|WP_003424284.1\|1900469_1901144_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|367360
NZ_CP045224.1\|WP_003424290.1\|1896791_1897409_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_003424273.1\|1904318_1905191_+\|MurR/RpiR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224651
NZ_CP045224.1\|WP_003424247.1\|1915798_1917016_+\|bifunctional-glutamate-N-acetyltransferase/amino-acid-acetyltransferase-ArgJ	unknown	unknown	gnl\|CDD\|239065
NZ_CP045224.1\|WP_003424276.1\|1903346_1903925_+\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|377744
NZ_CP045224.1\|WP_003424279.1\|1902573_1903290_+\|rRNA-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|224108
NZ_CP045224.1\|WP_003424286.1\|1898980_1900273_+\|diaminopimelate-decarboxylase	unknown	unknown	gnl\|CDD\|143501
NZ_CP045224.1\|WP_003424268.1\|1908623_1908797_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_003424257.1\|1911574_1912132_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228

Protein	Function_ID	Function_description	E-value
NZ_CP045224.1\|WP_003424249.1\|1914723_1915758_+\|N-acetyl-gamma-glutamyl-phosphate-reductase	gnl\|CDD\|234761	PRK00436, argC, N-acetyl-gamma-glutamyl-phosphate reductase; Validated.	5.49771e-179
NZ_CP045224.1\|WP_003424286.1\|1898980_1900273_+\|diaminopimelate-decarboxylase	gnl\|CDD\|143501	cd06828, PLPDE_III_DapDC, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase. Diaminopimelate decarboxylase (DapDC, EC 4.1.1.20) participates in the last step of lysine biosynthesis. It converts meso-2,6-diaminoheptanedioate to L-lysine. It is a fold type III PLP-dependent enzyme that contains an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain, similar to bacterial alanine racemases. DapDC exists as homodimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. Homodimer formation and the presence of the PLP cofactor are required for catalytic activity.	5.1589e-169
NZ_CP045224.1\|WP_003424267.1\|1908939_1909155_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|226181	COG3655, COG3655, Predicted transcriptional regulator [Transcription].	6.30851e-28
NZ_CP045224.1\|WP_003424287.1\|1897769_1898963_+\|aspartate-kinase	gnl\|CDD\|235843	PRK06635, PRK06635, aspartate kinase; Reviewed.	8.79458e-175
NZ_CP045224.1\|WP_003424252.1\|1913278_1914046_+\|YoaP-domain-containing-protein	gnl\|CDD\|379530	pfam14268, YoaP, YoaP-like. The YoaP-like domain is found at the C-terminus of the B. subtilis YoaP protein. It is found in bacteria and archaea, and is approximately 40 amino acids in length. The family is found in association with pfam00583. There is a single completely conserved residue A that may be functionally important.	5.60315e-14
NZ_CP045224.1\|WP_003424258.1\|1910618_1911317_-\|alpha/beta-hydrolase	gnl\|CDD\|274612	TIGR03502, lipase_Pla1_cef, extracellular lipase, Pla-1/cef family. Members of this protein family are bacterial lipoproteins largely from the Gammaproteobacteria. Characterized members are expressed extracellularly and have esterase activity. Members include the lipase Pla-1 from Aeromonas hydrophila (AF092033) and CHO cell elongation factor (cef) from Vibrio hollisae.	0.000240752
NZ_CP045224.1\|WP_003424254.1\|1912512_1912986_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379326	pfam13673, Acetyltransf_10, Acetyltransferase (GNAT) domain. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.50449e-48
NZ_CP045224.1\|WP_003424281.1\|1901297_1902383_-\|AI-2E-family-transporter	gnl\|CDD\|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	4.292e-37
NZ_CP045224.1\|WP_003424272.1\|1905343_1905529_-\|hypothetical-protein	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	3.23694e-06
NZ_CP045224.1\|WP_003424257.1\|1911574_1912132_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	3.82601e-09
NZ_CP045224.1\|WP_003424284.1\|1900469_1901144_+\|hypothetical-protein	gnl\|CDD\|367360	pfam03154, Atrophin-1, Atrophin-1 family. Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteristic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.	2.25319e-06
NZ_CP045224.1\|WP_003424273.1\|1904318_1905191_+\|MurR/RpiR-family-transcriptional-regulator	gnl\|CDD\|224651	COG1737, RpiR, Transcriptional regulators [Transcription].	1.10432e-65
NZ_CP045224.1\|WP_003424247.1\|1915798_1917016_+\|bifunctional-glutamate-N-acetyltransferase/amino-acid-acetyltransferase-ArgJ	gnl\|CDD\|239065	cd02152, OAT, Ornithine acetyltransferase (OAT) family; also referred to as ArgJ. OAT catalyzes the first and fifth steps in arginine biosynthesis, coupling acetylation of glutamate with deacetylation of N-acetylornithine, which allows recycling of the acetyl group in the arginine biosynthetic pathway. Members of this family may experience feedback inhibition by L-arginine. The active enzyme is a heterotetramer of two alpha and two beta chains, where the alpha and beta chains are the result of autocatalytic cleavage. OATs found in the clavulanic acid biosynthesis gene cluster catalyze the fifth step only, and may utilize acetyl acceptors other than glutamate.	0
NZ_CP045224.1\|WP_003424276.1\|1903346_1903925_+\|methyltransferase-domain-containing-protein	gnl\|CDD\|377744	pfam06962, rRNA_methylase, Putative rRNA methylase. This family contains a number of putative rRNA methylases. Note that many family members are hypothetical proteins.	7.51313e-74
NZ_CP045224.1\|WP_003424279.1\|1902573_1903290_+\|rRNA-pseudouridine-synthase	gnl\|CDD\|224108	COG1187, RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis].	4.04358e-99
NZ_CP045224.1\|WP_003424265.1\|1909165_1909633_-\|DUF2975-domain-containing-protein	gnl\|CDD\|378586	pfam11188, DUF2975, Protein of unknown function (DUF2975). This family of bacterial proteins have no known function. These proteins are likely to be integral membrane proteins. The proteins contain a highly conserved glutamic acid close to their C-terminus.	0.000275657

>NZ_CP045224.1|WP_003424272.1|1905343_1905529_-|hypothetical-protein
MKIHNLRYTGASLLHLVGTNMKIVSERFCHTDLKLTMNIYSYVLEEMYKKTSNNLSKILFR
>NZ_CP045224.1|WP_003424273.1|1904318_1905191_+|MurR/RpiR-family-transcriptional-regulator
MEETNEMKDSKHLISNIQSQYTRLSKGQKLIAQYILNNYDKVAFMTACKLGETVGVSESTVVRFANALGYSGYPKLQAALQELIKNKLTTVQRVEMAHDYSDDFAILNKVLKSDIDNIRSTLEEIDERAFKEASNKLLRARKIYILGMRSSFVVAQYLGFYLDIILDNVHIIRMDMGDAFEQIVRINEEDVIVAISFPRYSKKSYQIVNYAKEKGAHVISLTDSLFAPVASLADNTLLVKSNMASFVDSLVPALSISNALAISVGMKEKEDIKQHFDDLEQIWKRYSVYE
>NZ_CP045224.1|WP_003424276.1|1903346_1903925_+|methyltransferase-domain-containing-protein
MAYAKYLTKITDINKFYLENIINEGDIVIDATMGNGYDTRYLAEKVGEKGFVYAFDIQEEAIKSTRKKLEKEGYTDRVKLIFDGHEKMNQYIKEEVSCVLFNLGYLPRAKHSIITKPDTTLKAIKLSLEMLKENGVISIAIYTGHDGGQEEKDCIYNLVNNLNQDEFNVLESKFLNQVNNPPQLILIEKKKA
>NZ_CP045224.1|WP_003424279.1|1902573_1903290_+|rRNA-pseudouridine-synthase
MRINKYIASCGIASRRKAEEIILEGRIKVNGSIVKELFFNVDEEKDIVEFDNKKVKPSENYIYIVLNKPEGYITTVKDQFNRPSVIDILKDVKERVYPIGRLDYETSGLLILTNDGDLTYKLTHPKHEIDKTYVASVKGIISGDEIRKFETGLKIEDYTTAPAKIKVTKENKEKNYSVCEITIHEGRNRQVRKMCKAINHPVLNLRRISVGKIVLKDTKVGEYRYLTEDEIKYLKSIK
>NZ_CP045224.1|WP_003424281.1|1901297_1902383_-|AI-2E-family-transporter
MIIISKENIKYYLIVVFIGILFFKFINTPSDFISSIEGFLKFFSPFLLAILLALLLNPLVMLFEVKFKAHRLLAIFLSYIFIGFILAFAIRLLIPSIANTLNRLINEMPMYTDYINSFIEKNMSNIDFLKTLIPHIQHSLDNVLKEASNFIGKISKNFLIYTLSISSMLFNMTMGFILSIYIIYDKEKIALGFKRFLYSSTTRNKADSIIEFFRTTHDIFYDYLLGRILDSLIIGIIAFLGFQFVIRIENALFLASIIFLGNIIPYFGPFIGAIPPIAMTILYSPQKTIWVIAFLFILQQLDGNFIEPKVMGNQVGIGAIWVISAILVGQSLFGFIGVFLSVPIAAVVKTYVDKYIDNRLQ
>NZ_CP045224.1|WP_003424284.1|1900469_1901144_+|hypothetical-protein
MTRRDLMRGRVILLISILSIFLVGCSFNKKDEINLVEQGKTYLEKHNYKKAMESLSSALEEDSTNENARAMYMQAMRMSNMTEFEELKNYEGAIKELKLIEKIKNGSSVIKEEATKKKEELTKLEKEQNEAEEQRKKKAKDTAGEDRYRVESDARKSSYSGSSKNNKSSSKNNKKSDSDKSDNNNNSSQNQEKPNSSNPTPAPTPQDTSGGSDSSGNSQNSNNQ
>NZ_CP045224.1|WP_003424286.1|1898980_1900273_+|diaminopimelate-decarboxylase
MKLHGTMTVNNDELYIGGVSCLELSKKYQTPLYVFDEALVRQNCREYIKYFRAREGKNKVAYAGKAFLPLYMCNLINEEQMCLDVVSGGELYTAYKSNFPMEKVFFHGNNKTKEEINMGLDLGVGKFVVDNFYELDLLEALCEDKGKTQEIYFRITPGIEAHTHDYIKTGQIDSKFGFALVNGDLFRAIEKLSDYKNIKLVGLHAHIGSQIFDVEPYIDTVDIMMNLVKEIKEKFNIHLTEIDLGGGVGVYYSEGDKPKTIKEFCETIITKAETSCKELGIEVPTLVIEPGRSIVANAGSTLYTVGSIKDIKDVRVYVSVDGGMTDNVRPSLYQASYECSIVNKINHKAMNHVTIAGKCCESGDILIGDINIMDIKSGDILITTSTGAYGYSMSSNYNKIPRAAVVSVFDGNDKIICKRQSYEDLLALEV
>NZ_CP045224.1|WP_003424287.1|1897769_1898963_+|aspartate-kinase
MSIIVQKYGGSSVADTEKIKSIAENIIERRKENPQMVIVVSAMGKSTDEYITLAKELSNEPSKRELDALMSTGEMISASLLSIALNALGCKAISYNAYQLNIKTSGLHGKSQIDDINVNRIKNSLDEGNVVIVTGFQGINEDGDVTTLGRGGSDTSAVALAVKLNGKCEIYTDVDGIYFTDPRKYSKASKLDEIEYEEMLELASLGAQVMHSRSIELAQKYGVEIYVGRTCGTEKGTYIRGGKDMKLEDKVITGLATSDDDSSITIKDFKAENISSLFEDIATIGISVDMISQTAPILDKISVSFTVPKEELGECKKIVSKYTDEEHVVIDNNITKFSLVGLGMKNTSGVAAKVFKIFNENGIMIKLITTSEIRITCAINSDDKQVAIEKIAEVFNI
>NZ_CP045224.1|WP_003424290.1|1896791_1897409_+|hypothetical-protein
MTNMEKEILLLISRVRCVTESQFRKIYGDQKRYNKKNFKKTLRKMCSEYTLKKYPCDVDYYNYKDLSYVYYLNGSKLFKGDDLIKALVGSELVVRINTAGCDVKRFYRNVSVDDVKYDLFIEYTDQFGNIKQVLVDVDLNNEIDISKYENLSKKIDKSTIPFFKVPNVLVVTPDNLSELNDLERYDNEYSINFIDLGLNKLFNCI
>NZ_CP045224.1|WP_003424292.1|1894921_1896622_+|hypothetical-protein
MKRYLKTYGVALIIVIIYAFIKLPVLRLDFTSLFSVGIIFFVVAGILDMMLDRNERASKMAKYNFSIAIALLVYIVVVPFITSTPVFHAKSYRELLGKVTESKFTDDISPVSVNDIRLVDEDMAMKLGDKKLGEVPAIGSVSKLGKFHIQNVDGELYWVAPLVHRDIIKWITSLSGTSGYVKVSASNPQDVQLVQEIDGKPIKIVYQPEAYLHQDLQRHLYIHGIVNVGMTDFTLEINDEGRPYWVVSLYEHKIGYGGANATGIATVDAETGKINVYDVKNTPKWVDRIQPQNFITDQIKDWGVYVNGFLNSVISEKGVLVPTEGTSLVYGNDNRSYWYTGITSSGGDESTIGFMLVDSRTKEARLYKQPGATETAAMKSAEGNVQEKNYEATFPVMYNILGQPTYVSSLKDKAGLVKRVAFVSVEDYNVLGIGEDKNEALRNYKDALESKGNDLKLDNELKDEVIEGTITRISPDVRGGNTNYYVTLDTNKGIIFRATSKVSSELPLTQVGDKVKISYSKEESGVIEMSEFDNLNIANFEDKKAKEGTGTDENTDSQDSENQGNV
>NZ_CP045224.1|WP_009905700.1|1907430_1907715_+|hypothetical-protein
MIVYNKNFYPNDIFSRLDFSKIKRQLKLIDNELSDFGNICIIEKEHYTISVNSIGEINVYYDLEYENKVYGIVEEIEKLFKSQVGKFSISTYRN
>NZ_CP045224.1|WP_003424268.1|1908623_1908797_-|hypothetical-protein
MKRKLSTYFKGYVLGLCIAFLLFSFILKKLMISNIIGIVIGTGIAFLLICLFNKKRK
>NZ_CP045224.1|WP_003424267.1|1908939_1909155_-|helix-turn-helix-transcriptional-regulator
MAIVVNLDVMMAKRKISLKDLAEKIDITNANLSILKTGKAKAIRFTTLNEICKALDCQPGDILEYVEDENE
>NZ_CP045224.1|WP_003424265.1|1909165_1909633_-|DUF2975-domain-containing-protein
MITKFFSNILSVFLYFLLSLLGVAGIIFLCMIPMFLYDFSSDKVIALITRILYFSDYFVVILFLIFIINSTKYSPFILENVKRFKMMGCCLLVNTIIECVVGYKSNTSLIMIFGDNSGGISPLMVISFIFALMCFVIAETFDKAIKIKKDNDLTI
>NZ_CP045224.1|WP_003424258.1|1910618_1911317_-|alpha/beta-hydrolase
MEKKYFKIHGVPSILWGNPSSKLYIYIHGQCGNKEEAEAFANIAVPQECQVLSVDLPEHGERKGEKNSFDPWHVVPELVSIMEYAKCHWNQISLYANSIGAWFSMLSFEKENLRECIFVSPILDMQQLISNMMLWANVSEEQLKHELIIPTSFGHTLSWEYLQYVKQHPIIQWNVPTKILYGKHDELTEIGVVEKFVEKFNCNLTIMEDGKHWFNTPQELNSLYEWLNTLVK
>NZ_CP045224.1|WP_003424257.1|1911574_1912132_+|TetR/AcrR-family-transcriptional-regulator
MRVSREIVIQATSDIVNKDGLNKVSLKVIAENLGIRTPSLYNHIESLDDLLLEVAHKGMREMNNQMTKAVIGNFGDTAIKCISIAYFNFIISNPGVYETIQWATWHGNNETLEIFDEYKSLLEKLILSCNLNTKNTGEVLNLIMSVLHGYSTLQLGKSLMSKEEAIKGLTDSIDTVLLGIHKKYD
>NZ_CP045224.1|WP_003424254.1|1912512_1912986_-|GNAT-family-N-acetyltransferase
MFNEHLIRELKEDDIKDALELIWNVFEEFESPDYCDEGIMTFHQFIEYNSIIEKVKEKTLFFWGCFDCEKLIGVLAIRDLNHICMLFVDKNYHKRGVAKKLMTIGIEYCICNKFSLTEITVNSSPYAVEVYHKLGFKDTAVEQISDGIRFTPMKLLI
>NZ_CP045224.1|WP_003424252.1|1913278_1914046_+|YoaP-domain-containing-protein
MQIIDININNIDNEHICCSISEKKGENCVFSKKLWMKNNFDKGLVFKRFDVRGKAFIEYIPAENAWCPIIADNYMFINCFWISGKFKGKGYSNLLLQECVDDAKLKGKYGLVVLSSSKKMPFLSDAKYLKYKRFRLADTSVPNYELLYFPFTDNTPIPCFKNCVKQRKLNENGIVLYYSNQCPHTEKYALILKKIANSRGIDANLIKFETANEAQNAPAPFTAYSLFFNGEFVTNEVLSEKKIEKFLENEVKKFN
>NZ_CP045224.1|WP_003424249.1|1914723_1915758_+|N-acetyl-gamma-glutamyl-phosphate-reductase
MSKIKVGIIGATGYVGAELIRLLINHDKAELTAIGSNSYVGKDIVDIYPSIGYKNNMICIENEKVIDVCDVVFTALPHGVSEKFVIKAIKSKKKVIDLGADFRIKDEEVYSKWYGVSFIDKILHKKAVYGLSEIYKDDIKDADIIANPGCYPTSISLPLMPLLSSKLIKSNNIIIDSKSGLTGAGRELSISSHFTEVNENITAYKIGKHRHTPEIEQNLSESCQEKVSVVFTPNLIPVNRGILSTIYCTKADNISINDIHRKLTDYYEFKEFIEVLPLDKVASLKNVRFSNKCVISLHENVDTLIICSAIDNMIKGAAGQAIQNMNIMFGIEENTGLKNIVPSF
>NZ_CP045224.1|WP_003424247.1|1915798_1917016_+|bifunctional-glutamate-N-acetyltransferase/amino-acid-acetyltransferase-ArgJ
MEIIKGGVTVSEGFFASGIHCGLRKNKEKRDLALVYSDVLCDAAAVVTQNKVKGNPVYVTQEHIKNGKAQAIIVNSANANTFNGKEGLINAYKMAKFTSDKLKIKESDVLVASTGVIGKPLNIDLIEENMDELVNNLSKQGHIGAREAIMTTDIIKKEIAVAIMYGDKKITIGGMAKGSGMIHPNMATTLGFITTDANIDGVLLKEALKIAVDKSFNRVSVDGDTSTNDMVMILANGKAKNDRINKKDEHYQVFLSALTYVCIELAKLVAKDGEGCTKLIECYINGALSEEHAVKLAKTVISSSLVKTAVFGADANWGRILCALGYAGEEIDMEKVDIIFESMKGYIEVCKNGNGLDFNEEKAKKILEDDEISILVDLNMGNARGNAWGCDLSYDYVRINGSYRN

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Crispr_ID: NZ_CP045224_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045224_10

2318759-2319907

TypeV

I-A

Consensus_repeat	Method
GTTTTATATTAACTATGTGGTATGTAAAT	PILER-CR
ATTTACATACCACATAGTTAATATAAAAC	CRISPRCasFinder
ATTTACATACCACATAGTTAATATAAAAC	CRT

17 spacers

cas14j

The CRISPR arrays of NZ_CP045224_10

>merge|NZ_CP045224|10|2318759-2319907|PILER-CR,CRISPRCasFinder,CRT
ATTTACATACCACATAGTTAATATAAAACATTCGCAAGTTCTTAATCAAAAACCCAATTTTCTTTATTTACATACCACATAGTTAATATAAAACGCTAGTTGTACTTAACCAATAGCCAAATTGTTGACTTCATTTACATACCACATAGTTAATATAAAACTATTATTATTTACACATTTACTTTCAAAACTTCTTTTATTTACATACCACATAGTTAATATAAAACTATCCTAAGAATTCTCTCTTAGCATTTGGACATCTTAATTTACATACCACATAGTTAATATAAAACACTCCTGTAGTATTTTCAAAAGTTATTGCGCTAAGCAAATTTACATACCACATAGTTAATATAAAACAAGAACGTGCGCTTATTCTTGGATATCAATATAAAGAATTTACATACCACATAGTTAATATAAAACCCATGTTCATTTCGCCTTTAAATTCAACTTTCTCATAATTTACATACCACATAGTTAATATAAAACAAGAAGGTGAAATAATATTCTATGAAGGGCAATTAAAATTTACATACCACATAGTTAATATAAAACCTTGATGTTTAGCTTTTTGAAATAATTCAAGTTTTAAATTTACATACCACATAGTTAATATAAAACTTTTAAATAACCCCCCTCCCCTTCTGATTTTTTCGTGATTTACATACCACATAGTTAATATAAAACCGCCCTTTTCGCTATTATTTTTTTTATAACCCTTCAATTTACATACCACATAGTTAATATAAAACTGAAAAATTAAAAGAATTAATAGATAAGCAATTAATAATTTACATACCACATAGTTAATATAAAACCTTCTCTGAAAATCGTATATTCTTTTTTAAAAGAGTTATTTACATACCACATAGTTAATATAAAACGAACTAACCTCGTTTCCTGTGTTAATAAACTATGATATTTACATACCACATAGTTAATATAAAACCAGGACAAAATAGATTATTTGACTGGTTAAGAAATAAATTTACATACCACATAGTTAATATAAAACAGTTTATTTGGGGATTAGATAAAAATAAGGTAGCATCATTTACATACCACATAGTTAATATAAAACAATCTGTTTTTCTTCTTCTTCTGCATTATCTACAAGATTTACATACCACATAGTTAATATAAAAC

>NZ_CP045224|10|5|2318759-2319907|PILER-CR
ATTTACATACCACATAGTTAATATAAAAC	ATTCGCAAGTTCTTAATCAAAAACCCAATTTTCTTT
ATTTACATACCACATAGTTAATATAAAAC	GCTAGTTGTACTTAACCAATAGCCAAATTGTTGACTTC
ATTTACATACCACATAGTTAATATAAAAC	TATTATTATTTACACATTTACTTTCAAAACTTCTTTT
ATTTACATACCACATAGTTAATATAAAAC	TATCCTAAGAATTCTCTCTTAGCATTTGGACATCTTA
ATTTACATACCACATAGTTAATATAAAAC	ACTCCTGTAGTATTTTCAAAAGTTATTGCGCTAAGCAA
ATTTACATACCACATAGTTAATATAAAAC	AAGAACGTGCGCTTATTCTTGGATATCAATATAAAGA
ATTTACATACCACATAGTTAATATAAAAC	CCATGTTCATTTCGCCTTTAAATTCAACTTTCTCATA
ATTTACATACCACATAGTTAATATAAAAC	AAGAAGGTGAAATAATATTCTATGAAGGGCAATTAAA
ATTTACATACCACATAGTTAATATAAAAC	CTTGATGTTTAGCTTTTTGAAATAATTCAAGTTTTAA
ATTTACATACCACATAGTTAATATAAAAC	TTTTAAATAACCCCCCTCCCCTTCTGATTTTTTCGTG
ATTTACATACCACATAGTTAATATAAAAC	CGCCCTTTTCGCTATTATTTTTTTTATAACCCTTCA
ATTTACATACCACATAGTTAATATAAAAC	TGAAAAATTAAAAGAATTAATAGATAAGCAATTAATA
ATTTACATACCACATAGTTAATATAAAAC	CTTCTCTGAAAATCGTATATTCTTTTTTAAAAGAGTT
ATTTACATACCACATAGTTAATATAAAAC	GAACTAACCTCGTTTCCTGTGTTAATAAACTATGAT
ATTTACATACCACATAGTTAATATAAAAC	CAGGACAAAATAGATTATTTGACTGGTTAAGAAATAA
ATTTACATACCACATAGTTAATATAAAAC	AGTTTATTTGGGGATTAGATAAAAATAAGGTAGCATC
ATTTACATACCACATAGTTAATATAAAAC	AATCTGTTTTTCTTCTTCTTCTGCATTATCTACAAG
ATTTACATACCACATAGTTAATATAAAAC

>NZ_CP045224|10|8|2318759-2319907|CRISPRCasFinder
ATTTACATACCACATAGTTAATATAAAAC	ATTCGCAAGTTCTTAATCAAAAACCCAATTTTCTTT
ATTTACATACCACATAGTTAATATAAAAC	GCTAGTTGTACTTAACCAATAGCCAAATTGTTGACTTC
ATTTACATACCACATAGTTAATATAAAAC	TATTATTATTTACACATTTACTTTCAAAACTTCTTTT
ATTTACATACCACATAGTTAATATAAAAC	TATCCTAAGAATTCTCTCTTAGCATTTGGACATCTTA
ATTTACATACCACATAGTTAATATAAAAC	ACTCCTGTAGTATTTTCAAAAGTTATTGCGCTAAGCAA
ATTTACATACCACATAGTTAATATAAAAC	AAGAACGTGCGCTTATTCTTGGATATCAATATAAAGA
ATTTACATACCACATAGTTAATATAAAAC	CCATGTTCATTTCGCCTTTAAATTCAACTTTCTCATA
ATTTACATACCACATAGTTAATATAAAAC	AAGAAGGTGAAATAATATTCTATGAAGGGCAATTAAA
ATTTACATACCACATAGTTAATATAAAAC	CTTGATGTTTAGCTTTTTGAAATAATTCAAGTTTTAA
ATTTACATACCACATAGTTAATATAAAAC	TTTTAAATAACCCCCCTCCCCTTCTGATTTTTTCGTG
ATTTACATACCACATAGTTAATATAAAAC	CGCCCTTTTCGCTATTATTTTTTTTATAACCCTTCA
ATTTACATACCACATAGTTAATATAAAAC	TGAAAAATTAAAAGAATTAATAGATAAGCAATTAATA
ATTTACATACCACATAGTTAATATAAAAC	CTTCTCTGAAAATCGTATATTCTTTTTTAAAAGAGTT
ATTTACATACCACATAGTTAATATAAAAC	GAACTAACCTCGTTTCCTGTGTTAATAAACTATGAT
ATTTACATACCACATAGTTAATATAAAAC	CAGGACAAAATAGATTATTTGACTGGTTAAGAAATAA
ATTTACATACCACATAGTTAATATAAAAC	AGTTTATTTGGGGATTAGATAAAAATAAGGTAGCATC
ATTTACATACCACATAGTTAATATAAAAC	AATCTGTTTTTCTTCTTCTTCTGCATTATCTACAAG
ATTTACATACCACATAGTTAATATAAAAC

>NZ_CP045224|10|7|2318759-2319907|CRT
ATTTACATACCACATAGTTAATATAAAAC	ATTCGCAAGTTCTTAATCAAAAACCCAATTTTCTTT
ATTTACATACCACATAGTTAATATAAAAC	GCTAGTTGTACTTAACCAATAGCCAAATTGTTGACTTC
ATTTACATACCACATAGTTAATATAAAAC	TATTATTATTTACACATTTACTTTCAAAACTTCTTTT
ATTTACATACCACATAGTTAATATAAAAC	TATCCTAAGAATTCTCTCTTAGCATTTGGACATCTTA
ATTTACATACCACATAGTTAATATAAAAC	ACTCCTGTAGTATTTTCAAAAGTTATTGCGCTAAGCAA
ATTTACATACCACATAGTTAATATAAAAC	AAGAACGTGCGCTTATTCTTGGATATCAATATAAAGA
ATTTACATACCACATAGTTAATATAAAAC	CCATGTTCATTTCGCCTTTAAATTCAACTTTCTCATA
ATTTACATACCACATAGTTAATATAAAAC	AAGAAGGTGAAATAATATTCTATGAAGGGCAATTAAA
ATTTACATACCACATAGTTAATATAAAAC	CTTGATGTTTAGCTTTTTGAAATAATTCAAGTTTTAA
ATTTACATACCACATAGTTAATATAAAAC	TTTTAAATAACCCCCCTCCCCTTCTGATTTTTTCGTG
ATTTACATACCACATAGTTAATATAAAAC	CGCCCTTTTCGCTATTATTTTTTTTATAACCCTTCA
ATTTACATACCACATAGTTAATATAAAAC	TGAAAAATTAAAAGAATTAATAGATAAGCAATTAATA
ATTTACATACCACATAGTTAATATAAAAC	CTTCTCTGAAAATCGTATATTCTTTTTTAAAAGAGTT
ATTTACATACCACATAGTTAATATAAAAC	GAACTAACCTCGTTTCCTGTGTTAATAAACTATGAT
ATTTACATACCACATAGTTAATATAAAAC	CAGGACAAAATAGATTATTTGACTGGTTAAGAAATAA
ATTTACATACCACATAGTTAATATAAAAC	AGTTTATTTGGGGATTAGATAAAAATAAGGTAGCATC
ATTTACATACCACATAGTTAATATAAAAC	AATCTGTTTTTCTTCTTCTTCTGCATTATCTACAAG
ATTTACATACCACATAGTTAATATAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045224.1\|WP_032510205.1\|2308455_2309229_-\|ABC-transporter-permease	unknown	unknown	unknown
NZ_CP045224.1\|WP_003420348.1\|2309234_2310122_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213231
NZ_CP045224.1\|WP_003420338.1\|2316814_2317366_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380339
NZ_CP045224.1\|WP_003420340.1\|2315661_2316624_-\|cysteine-synthase-family-protein	unknown	unknown	gnl\|CDD\|107204
NZ_CP045224.1\|WP_003420336.1\|2317900_2318188_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_003420322.1\|2327508_2328966_-\|aminomethyl-transferring-glycine-dehydrogenase-subunit-GcvPB	unknown	unknown	gnl\|CDD\|235292
NZ_CP045224.1\|WP_003420346.1\|2310134_2311157_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_003420319.1\|2328965_2331440_-\|aminomethyl-transferring-glycine-dehydrogenase-subunit-GcvPA	unknown	unknown	gnl\|CDD\|234769
NZ_CP045224.1\|WP_041160405.1\|2322110_2323229_+\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	cas14j	-	gnl\|CDD\|223747
NZ_CP045224.1\|WP_003420306.1\|2337931_2339791_-\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|238923
NZ_CP045224.1\|WP_003420312.1\|2336232_2337030_+\|lipoprotein	unknown	unknown	gnl\|CDD\|224381
NZ_CP045224.1\|WP_003420313.1\|2334936_2335923_+\|lipoate--protein-ligase	unknown	unknown	gnl\|CDD\|161920
NZ_CP045224.1\|WP_003420345.1\|2312205_2312382_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_003420307.1\|2337132_2337732_+\|TerD-family-protein	unknown	unknown	gnl\|CDD\|226595
NZ_CP045224.1\|WP_003420342.1\|2313533_2315381_-\|glycerophosphodiester-phosphodiesterase	unknown	unknown	gnl\|CDD\|176521
NZ_CP045224.1\|WP_003420315.1\|2332722_2334453_-\|Na+/H+-antiporter-NhaC-family-protein	unknown	unknown	gnl\|CDD\|224671
NZ_CP045224.1\|WP_003420354.1\|2306211_2307615_-\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NZ_CP045224.1\|WP_003420327.1\|2324331_2324649_+\|pyrimidine/purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|377724
NZ_CP045224.1\|WP_003420325.1\|2324733_2327091_-\|HAD-IC-family-P-type-ATPase	unknown	unknown	gnl\|CDD\|319795
NZ_CP045224.1\|WP_003420352.1\|2307618_2308344_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816

Protein	Function_ID	Function_description	E-value
NZ_CP045224.1\|WP_003420307.1\|2337132_2337732_+\|TerD-family-protein	gnl\|CDD\|226595	COG4110, COG4110, Uncharacterized protein involved in stress response [General function prediction only].	7.68444e-79
NZ_CP045224.1\|WP_003420348.1\|2309234_2310122_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213231	cd03264, ABC_drug_resistance_like, ABC-type multidrug transport system, ATPase component. The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	6.28598e-107
NZ_CP045224.1\|WP_003420338.1\|2316814_2317366_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|380339	cd02209, cupin_XRE_C, XRE (Xenobiotic Response Element) family transcriptional regulators, C-terminal cupin domain. This family contains transcriptional regulators containing an N-terminal XRE (Xenobiotic Response Element) family helix-turn-helix (HTH) DNA-binding domain and a C-terminal cupin domain. Included in this family is Escherichia coli transcription factor SutR (YdcN) that plays a regulatory role in sulfur utilization; it regulates a set of genes involved in the generation of sulfate and its reduction, the synthesis of cysteine, the synthesis of enzymes containing Fe-S as cofactors, and the modification of tRNA with use of sulfur-containing substrates. This family belongs to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	1.67456e-17
NZ_CP045224.1\|WP_003420340.1\|2315661_2316624_-\|cysteine-synthase-family-protein	gnl\|CDD\|107204	cd01561, CBS_like, CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine. Deficiency of CBS leads to homocystinuria, an inherited disease of sulfur metabolism characterized by increased levels of the toxic metabolite homocysteine. Cysteine synthase on the other hand catalyzes the last step of cysteine biosynthesis. This subgroup also includes an O-Phosphoserine sulfhydrylase found in hyperthermophilic archaea which produces L-cysteine from sulfide and the more thermostable O-phospho-L-serine.	1.60519e-105
NZ_CP045224.1\|WP_003420306.1\|2337931_2339791_-\|EAL-domain-containing-protein	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	1.85153e-84
NZ_CP045224.1\|WP_041160405.1\|2322110_2323229_+\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl\|CDD\|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.00854e-54
NZ_CP045224.1\|WP_003420319.1\|2328965_2331440_-\|aminomethyl-transferring-glycine-dehydrogenase-subunit-GcvPA	gnl\|CDD\|234769	PRK00451, PRK00451, aminomethyl-transferring glycine dehydrogenase subunit GcvPA.	0
NZ_CP045224.1\|WP_003420312.1\|2336232_2337030_+\|lipoprotein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	3.07907e-94
NZ_CP045224.1\|WP_003420313.1\|2334936_2335923_+\|lipoate--protein-ligase	gnl\|CDD\|161920	TIGR00545, Probable_lipoate-protein_ligase_A, lipoyltransferase and lipoate-protein ligase. One member of this group of proteins is bovine lipoyltransferase, which transfers the lipoyl group from lipoyl-AMP to the specific Lys of lipoate-dependent enzymes. However, it does not first activate lipoic acid with ATP to create lipoyl-AMP and pyrophosphate. Another member of this group, lipoate-protein ligase A from E. coli, catalyzes both the activation and the transfer of lipoate. Homology between the two is full-length, except for the bovine mitochondrial targeting signal, but is strongest toward the N-terminus. [Protein fate, Protein modification and repair].	8.21907e-95
NZ_CP045224.1\|WP_003420322.1\|2327508_2328966_-\|aminomethyl-transferring-glycine-dehydrogenase-subunit-GcvPB	gnl\|CDD\|235292	PRK04366, PRK04366, aminomethyl-transferring glycine dehydrogenase subunit GcvPB.	0
NZ_CP045224.1\|WP_003420342.1\|2313533_2315381_-\|glycerophosphodiester-phosphodiesterase	gnl\|CDD\|176521	cd08579, GDPD_memb_like, Glycerophosphodiester phosphodiesterase domain of uncharacterized bacterial glycerophosphodiester phosphodiesterases. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in uncharacterized bacterial glycerophosphodiester phosphodiesterases. In addition to a C-terminal GDPD domain, most members in this family have an N-terminus that functions as a membrane anchor.	1.2911e-88
NZ_CP045224.1\|WP_003420315.1\|2332722_2334453_-\|Na+/H+-antiporter-NhaC-family-protein	gnl\|CDD\|224671	COG1757, NhaC, Na+/H+ antiporter [Energy production and conversion].	2.5665e-58
NZ_CP045224.1\|WP_003420354.1\|2306211_2307615_-\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.30987e-43
NZ_CP045224.1\|WP_003420327.1\|2324331_2324649_+\|pyrimidine/purine-nucleoside-phosphorylase	gnl\|CDD\|377724	pfam06865, DUF1255, Protein of unknown function (DUF1255). This family consists of several conserved hypothetical bacterial proteins of around 95 residues in length. The function of this family is unknown.	3.7867e-54
NZ_CP045224.1\|WP_003420325.1\|2324733_2327091_-\|HAD-IC-family-P-type-ATPase	gnl\|CDD\|319795	cd02609, P-type_ATPase, uncharacterized subfamily of P-type ATPase transporter, similar to uncharacterized Streptococcus pneumoniae exported protein 7, Exp7. This subfamily contains P-type ATPase transporters of unknown function, similar to Streptococcus pneumoniae Exp7. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids. They are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle. A general characteristic of P-type ATPases is a bundle of transmembrane helices which make up the transport path, and three domains on the cytoplasmic side of the membrane. Members include pumps that transport various light metal ions, such as H(+), Na(+), K(+), Ca(2+), and Mg(2+), pumps that transport indispensable trace elements, such as Zn(2+) and Cu(2+), pumps that remove toxic heavy metal ions, such as Cd(2+), and pumps such as aminophospholipid translocases which transport phosphatidylserine and phosphatidylethanolamine.	0
NZ_CP045224.1\|WP_003420352.1\|2307618_2308344_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	4.41058e-80

>NZ_CP045224.1|WP_003420336.1|2317900_2318188_-|hypothetical-protein
MKKFLYALYSFIVIIANFRLKEKNYNFILLAIFFILLLIQNGVLKTGYQNRATFYQDNYFNGEDKNDKIKFMTIKIFIFLSLPLCFNILFDYLTS
>NZ_CP045224.1|WP_003420338.1|2316814_2317366_+|helix-turn-helix-transcriptional-regulator
MSINTIIAKNLNRLRNERNLSLGQLAELSGVSKVMLSQIEKGDSNPTVNTIWKIASGLNVPYTAILEQPQNETFIVSKTDIDVQVSENKDYRLYCYYPNTPTRNFELFQMELEEGHSYTSVGHSEKSQEYIMIIEGQLKLEVNDSIYQLRENDSICFSAESMHTYHNQGEKTLKAVIINYYPV
>NZ_CP045224.1|WP_003420340.1|2315661_2316624_-|cysteine-synthase-family-protein
MRVLNNVTEAIGNTHMLHLSKIVDEFGVQGNIYAKMEYLNPGFSKKDRVALQMITEAENAGLLVPGQAVVELTSGNTGTGLAIACACKGYKFIACMSKGNSMERARMMKALGAEVVLVDQMPNSVHGQVSGEDLALVEIEAQRITKERNAFRADQFNLEACNHAHENYTAEEMWEQLDGNIDVFVDFLGSGSTFAGCSKALKGHKSSIKCYVVEPKTAAIYSGKEITDQGHKIQGGGYSMDLPLVDKKLIDGYIQITDEEATDVARKLAKLEGVFAGFSSGANVCAAIKLLKSTERGKNIVLTLNDSGLKYLSTDLYEEL
>NZ_CP045224.1|WP_003420342.1|2313533_2315381_-|glycerophosphodiester-phosphodiesterase
MTKRVLSNFTLTGKNILSKFIFMIRYNFSTLILFELFYKGLALLLILPSIKYIFDNLLKSLNIFYLNMDNIIKILSNPISIVLIILSVIILAFYAFFEFTSVIICFNRSIKCEKIGLFELIKMSFKKSINLLYPKNILLFIFVLLIIPLVNTVLISGFIGKIQIPDYILDYIKSNNILNIVYMISLFIIYILVIRWIFSVHEITLNTENFKIARKESVNLIKGRIIRTVIYSLILSLVMAIIGYVIYHIGIISIGIWTKYYTNIGSLKELFINRCISFEDYFSLILSIFIFIVDIAFISATYYEYKGVNISRNNIIKEKKSIPKTIFKLSLIILIFCVESNAYSSHVNGLFNTSFSFNTTTIAHRAGAERAPENTLIALKEALNAKADYAEIDVQETKDGELIILHDSNFKRTTRVDKNVWDVNYDEVRTYDAGSFYYDGKGYYDERFVGEKIPTLDEMIKYSKGRIKLLIEIKLTGHEKGDVTKKVVQLIKENNFENQCIIASMDKTVLQKVKKLDKNLMTCYFMAVAYGDFSKLNYIDVYGIESTFVNTTVVEKIHKMNKKIFVWTVNSYSLIEKMLDLNVDSIITDNPYLVDGAIVWKKNGFINKVSDYLFS
>NZ_CP045224.1|WP_003420345.1|2312205_2312382_+|hypothetical-protein
MFIGEIDKCTHILTAYISSSYDYCNFLDTQLDDFISEYGETVVEICLYQVLLLVSRYN
>NZ_CP045224.1|WP_003420346.1|2310134_2311157_-|hypothetical-protein
MVNWEIKKLIKSKSMFISLGILILILSINIFVKPVLETENYYIDKERGRIEDTRNSEEIGNYKFQNKINVLKQLSSQKDMDVFSKKIKSISTNKLYNLIINEYKDVSFWKVFNYRATNSLINVGMLIIIVIIISNIYVDELVFSVRDIILSSKEKKKALNSKIVIAFLVPLTIYSVYLIGIFITTCMQQGMPINGDLEAFRIVDNIATLKCNSSIINYVISNIGIEFLMFEGLAMIALLGSFISKSSITSISFFIFTIVITKIISVIHILPKNLLLAISTVNYYDLIFGFNKIIGNYLGEIIIFKIHIDIVNLLIGVLVAIFIGAMSFCFIIIKSDYISK
>NZ_CP045224.1|WP_003420348.1|2309234_2310122_-|ABC-transporter-ATP-binding-protein
MNKLEIKNLSKIYGKKVANDKITVTLENGVYGLLGPNGAGKSTLMKQITTLIKPDEGQIFYNGEDIFKMDDDYRNILGYLPQEFGVYKNFTAKEFLQYIGALKGLKGKYLSSKIEELLDLVGLYDVRDKSIGKFSGGMKRRVGIAQVLLNDPKIIVLDEPTAGLDPQERARFRNLIAKISRNKIIVLSTHIISDIESVAKETIMIKDGKLLMKGTHKEILSHMENKVYNVQVKNECEVDDIQSKYKVVSIQSDIDSIVLRIVSEDIPIGDNIQPVQAKFEDVYMFYFDLEDAREA
>NZ_CP045224.1|WP_032510205.1|2308455_2309229_-|ABC-transporter-permease
MMYLVKIEMIKILKSKSVWIIWLFLLFFGFVLIRKFDVLDTYADIFYKIEGSIPLIGLIMFIITSGNYIKEYDSNMTGLINTTKNGKKSVVLSKLVANGLILSIINISFILLVGIRGFSFFDFKNLNEPIHNLWYFGNSSLNLTVIQMYIIVILTTIFASFVFAQIGLTLSSIFKSAVIPFILGGLIMAIPYFSVGFIPDKAIKFMSVTPNWIMMSQQIVRYNVPSILIGFSIVISIILMIVLTKITYKNFTSSKRF
>NZ_CP045224.1|WP_003420352.1|2307618_2308344_-|response-regulator-transcription-factor
MENRVLIIDDEVEILKLLETVLKKEGLSNIYTAKTRKEGLEVFKNINPDLIILDIMLPDGEGYDICKEIRKTSNSPIIFLSAKTEELDKLLGLAIGGDDYVTKPFSPKEVAFRVKAHLRRLSYFSDSQNENTDSDNNEEKTISFGPYILNESRAELIKDGKSIGLSAKELKILSLFANNQNQIISKEKLWDKVWGEDYVGFDNTIMVHIRKIREKLEDNPSKPEYILTIKGLGYKLSVKED
>NZ_CP045224.1|WP_003420354.1|2306211_2307615_-|HAMP-domain-containing-histidine-kinase
MKWKITRNFIFTIVFVVISVVIINIISILYVISTDNFLKVVDSRNNPEEFARSFEKDLYEKDGELKLSKIGADKLEKSNSWIQVLNDLGEEVFGVNVPKDTPQKYTPFQMVNNYKYIETEYVNFVLEKYLNKKHLNIIVGIPSRDVSRIILTYSQNNTKKTLNKIIIIILVIDGMVALGVGYLFSRKLTKPISSVLWSIETMANGNYSLYLKDRGIYEEVFKNINMLADTLRVNEVERKENEELREEWLANITHDIKTPLASIQGYAEIINDKDYEFSEDEIREYAEIIYNKSKYIKDLVDDLNLSTRLKNNTIVLDKKKVNLVGLVRNIIIDILNDNRYKNRNIEFESNEDLIEVYVDSILFRRAITNLIFNSIVHNSEGTLISVKIVKKDNIEIIIKDSGVGISKNDLKHIFKKYYRGTNTGEMHKGSGLGMAISKEIIEIHKGKIYLNSEIGIGTEIIIEINQN
>NZ_CP045224.1|WP_041160405.1|2322110_2323229_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MVVVEKAYKFRMYPNKKQQELINKTFGCCRFVYNKYLAKRIDVYKNDKETFTYKQCSSDLTNLKKELKWLKEPDKFSLQNALKDLENAYEKFFKEKAGFPKFKSKKTNRFSYKTNFTNGNIMYCGQHIKLPKLGMVKIRDKQVPQGRILNATISKEPSGRYYVSLCCTDVDIEAFENTNNQIGLDLGIKEFCISSCGEFIENPKYLKKSLNKLAKLQRELSIKTIGSLNRNKARLKVARLQEHIANQRKDFLQKLSTKLIKENDIICIEDLQVKNMIRNRKLSRLISDVSWSEFIRQLEYKANWHGRKIVRVGKFFASSQICNKCGYKNEEVKNLNIREWICPSCNETHDRDINASMNILKEGLRLITIQNK
>NZ_CP045224.1|WP_003420327.1|2324331_2324649_+|pyrimidine/purine-nucleoside-phosphorylase
MNEFKNVTAVKKANVYFDGKVSSRVIILPNGERKTLGLMLPGEYTFSTREEEIMEILAGSMDVKLPGSNEFVTYKEGQKFNVPSDSSFDLKVNEVVDYCCSYIAD
>NZ_CP045224.1|WP_003420325.1|2324733_2327091_-|HAD-IC-family-P-type-ATPase
MGNLNLKRYNCDIKMGLSSEQIQSRIDNNLVNVFDNGKTKTYKQIFKDNVFTLFNLINIILVCLLVSVGSFKNTLFIFIAVINTIIGVIQEIRAKRLLDNLSVIVSNKVSVIRDKEKKEIDVQELVLDDIMILKTGNQICADSKVLDGRLEVNESLITGESDIVIKNKGDFLYSGSFVVSGEAFVRVENIGKDNYANKIANDAKISKKHNSQLRNSLNAILKVVGIIIIPLGLILFAKQHFGNGDSIVTSIVGTVAAVNGMIPEGLTLLTSIALALGTIKLASHKTLVQELYCVETLARVDTLCLDKTGTITEGKMQVDDVVMLEELDIDDIMGNICNALKDDNATLNAIRDKYSILDTHKVKNLIPFSSERKYSGVIFEGEGTYLLGAFEFIFKDKYKELKTEVEKYSKKGNRVIVLAHSNSYMEDNNIPEDIKPLAFILILDKIRDEAKETLEFFYNEGVDIKIISGDNPMTVSEVARKAGLKTAGNFIDATTLKNDEDIYEAVDKYNVFGRVSPQQKKQMILALKKQNHTVAMTGDGVNDVLALKEADCSIAMASGSDVTKNVSNLVLLDSNFASMPKVVMEGRKVINNIQRTASLFLVKTIFSFFLSILTLFFFSRQYPFVPIQLALIGAVTVGIPSFFLALEANRGRISGNFLLNILKNALPGALCVTINVIIVYNIVEYLGYNSSVFSTMCAILTGVCGLLILRQQCLPFNKERIFLIVSMTIAFIVGILFLGGLFSFVALSKQLILITVVLAVLMPIMIKVMRFVLDEILGAIVPNLN
>NZ_CP045224.1|WP_003420322.1|2327508_2328966_-|aminomethyl-transferring-glycine-dehydrogenase-subunit-GcvPB
MKEYNSLLIDISKKGRKAYSLPKLDIDDIKIEDMIDQNMIRKSELNLPEVGELELVRHYTLLSNKNFGVDTGFYPLGSCTMKYNPKINEDMAALPNFTGMHPYQSSDTAQGSLSLMYDLSRRLSEITGMDEVTLQPSAGSHGEFTGLMIIKAYHENRGDHKRTKVIIPDSAHGTNPASAAMANFDVIQIASDKNGAVDINALKEVLNDEVAALMLTNPSTLGLFEKNIKEIATLVHEAGGLLYYDGANMNAIMGITRPGNMGFDVVHLNLHKTFSTPHGGGGPGAGPVGVKKELVSFLPIPVIEKREDKYILNYDREKSIGKIKNFYGNFGVLVRAYTYILTMGRDGLKEASEMAVLNANYIKESIKDDYILPIDTLCKHEFVLGGLPRGEANIKTIDIAKRLLDYGYHPPTMYFPLIINEALMIEPTESESIETLDSFIDAMKSVAKEAKEEPELLKTAPHNTLVKRVDDARAVKKPILTWSQR
>NZ_CP045224.1|WP_003420319.1|2328965_2331440_-|aminomethyl-transferring-glycine-dehydrogenase-subunit-GcvPA
MNELKRVSLYNIHKELGAKLVEFAGWEMPLEYEGINKEHDMVRKSAGIFDVSHMGEVQIKGVESEKFIQNLVTNDISTLNINDIIYTPMCYENGGVVDDLLIYKFGEEDYLLVINAGNIDKDVAWIIKQSERYNVDIKNISSEVSQLAIQGPKAEEILQKITDIDLNSIKFYKSIPSVKVCGCPCLVSRTGYTGEDGFEIYCENKYAEIIWNEVLKVGGEDICPAGLGCRDTLRFEAALPLYGHEINEHISPVEGGLSIFVKTNKESFIGKSILSKEKENGAKRKLVGFEMQGKGMPRNGYDIRIGDKIVGFVTTGCASPTTGKILGMGIIDSEYAKVGNEIGIAIRKKVVPAVIAKKPFYKKQYKKDNIILNKENKFSYIPATSEDKSKMLKVVGLNSVDELFSDIPEEVKLKRDLNLEIGKSELEVSKIVKRLSEENLSLEDLTCFLGAGAYDHYIPSIIKHITSRSEFYTAYTPYQAEISQGTLQVVFEFQSMIAEITGMEIANASMYDGATSAIEACIMAMNQTRKNKIVVSKTTHPETLSVLRTYLQYKDCEIVEIDFCNEYGTTDIEKLKASVDKDTACVLIQTPNFFGIIEEMEEIEKITHENKAMLIMSVDPISLGVLKTPGEIGADIVVGEAQSLGNPLNFGGPYVGFLASKSKYTRKMPGRIVGQSLDTEGKIAYVLTLQTREQHVRREKATSNICSNQALNALVASIYMATMGKEGFKEVGMQSMKKAHYTYNKLVQTGKYKPIFKGKFFKEFAIQGNLNIETINDKLLEENILGGYNLEYNYPELKNSTLLCVTEKRSKEEIDKLVGIMEGL
>NZ_CP045224.1|WP_003420315.1|2332722_2334453_-|Na+/H+-antiporter-NhaC-family-protein
MRNKKINIIFLTTIMFIMSTVMVFAEEDIDTIALANAEKFGILTLIPPLVAIILAFITKNVIISLLIGILSGSFIIKASGINVFATFIQAFLDLVDRALVSLADPWNAGIILQVLAIGGVINLVAKMGGAKAIAEALAKRAKSAKGTQLITWFLGLLVFFDDYANSLIVGPMMRPVADKMKISREKLAFIIDATAAPVAGLAIISTWIGLEVGLIHDAFESISIDVDAFGIFLNTIPFRFYNILILAFIIISALLLKEFGPMRKAEIKSRSRKIDIDLDEGVEELDDLAPKNGVKLSVWNAIIPIGTLIIVALASFYYSGYTSIMGGEDKALIQLFTNSPYSFEAIKEAFSASDASRALFQSALVASLVAIIMAVIKKIFTISEAIDVWIDGMKSLVITGVILILAWSLSSVIKELGTAKFLIHLLSGSLPPFLLPSLIFGLGAIISFATGTAYGTMGILMPLAIPLAYSLNPDMSYVIVSTSAVLTGAIFGDHCSPISDTTILSSMGAGCNHIDHVNTQMPYAIFTAVITIVFGYIPAGLGLPIYIVLPVAIAAIFVGIQIIGKRVDEAEIELVE
>NZ_CP045224.1|WP_003420313.1|2334936_2335923_+|lipoate--protein-ligase
MLLIYNEKTNPYFNLAMEEYLLKNFDEDLFILWRNEPSIIVGKNQNTLSEINLEYIKEYSIPVVRRQSGGGAVFHDLGNINFTFIACNNNNFSDFRRFTQPIIDLLKTLDVNAEFSGRNDLLIDGKKFSGNAQYNYKNKVMHHGTLLFSSEINDLSKALKVKPIKFEGKGIKSVKSRVTNISEHLHSKMDILEFKDAIMNYLSKTNTDNTNYCLSELDIEQIEKLTKSKYETWDWNFGNSPKYTLSNELKYSGGNVEFNLNVDKGIITSIKFFGDFFGKCDVSFVENKLIGIRHEENALRNTLNSIEINDYFLGADTDILVSGILGVK
>NZ_CP045224.1|WP_003420312.1|2336232_2337030_+|lipoprotein
MKFKKLLCLLLCLVLTLAVVGCSKAKDDKKIVVGATLVPGGELLEELKPLIKEKGYTLEVKNFDDYILPNEALNNGEIDANLFQHEPYLKEAVKAKGYKIMAGKKLYVCPAILYSYKIKSVDEFKKGDTIAISNNPSSCSKNLRYLESIGLLTLPKGDGLVSPKDIIENPKGIQFKELDIAQIPSSLPDVTAAFIDTTYAVPAGLDAKKNGIYTAPINDEYANLLAFRTEDKDSEKIKVLQDVLTSDKARSLIEEKYKGIVIPTF
>NZ_CP045224.1|WP_003420307.1|2337132_2337732_+|TerD-family-protein
MAIELKKGQKINLTKKENSDLGEILVNLNWNQKVQKKGFFGSLRSSNIDLDLGCLFEMKNGVKGAVQALGNAFGSLDNPPFAQLDGDDRTGSNAQGENLRINGNKIKEIKRILIYAFIYEGVANWSEADGIVTIKQKQDSDLVVKLDEHKNGYNMCSIALIENVNDETFSVEKVVKYFKGHREMDTEFHWGLKWVAGRK
>NZ_CP045224.1|WP_003420306.1|2337931_2339791_-|EAL-domain-containing-protein
MKRFLRRIILVLFILLIFISFISIKLIHNVGDYGKLINYVGIVRGASQRLTKLEMNHKPNDELIEYIDEILQELITGHGNYGLVLTDCNKYNEDLLLLEKKWEDLNSEIKKVRMKEPNNQLLSISEEFFSLANDTVFEIENFSKEKSNYLMTLIIIISIIGILACIILILQYSKKMIKLEKLNVDLKNIAYKDELTGVNTIEKFKLDANQNICMHKDKKFAVFYIDFENFKYINDIFGYDYGDMILKRYANLMMNDIGKYEIFAREIADRFVALRCYIDKEDLVVRQRIVDSELINTTNEIKNKHSITVVSGICCIEDVNEKLSIDGLINRANFAQKTVKNKPGTNYAFYNDSIRKKMIEENTIKSRIHEAIEKREFIVYLQPKVNLHNQKINCAEALVRWLTPDKGIISPAIFIPVLEKNFFIALVDKYVFEEVCKWIRKRLDENKPFVQISVNVSRIQFYNTKFVETYSNIQNKYRIPKNTIEIEFTESVAFENQNHLLEIIHDLHENGFTCSLDDFGKGYSSLSVLKDLPFDALKLDSMFFKASLDKDKEKIVIKNIVHMLKELNITTVAEGIEYEEQVEFLRDIGCDLVQGFVFYKPMPILEFEEILDKEFVYNS

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Crispr_ID: NZ_CP045224_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045224_11

2466569-2466666

Orphan

Consensus_repeat	Method
TTTATCAAGTAAAATATAGTTATATTAATATAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045224_11

>merge|NZ_CP045224|11|2466569-2466666|CRISPRCasFinder
TTTATCAAGTAAAATATAGTTATATTAATATAATTATTTTAGATAATAAGGTAGAAATATTTTAGTTTATCAAGTAAAATATAGTTATGTTAATATAA

>NZ_CP045224|11|9|2466569-2466666|CRISPRCasFinder
TTTATCAAGTAAAATATAGTTATATTAATATAA	TTATTTTAGATAATAAGGTAGAAATATTTTAG
TTTATCAAGTAAAATATAGTTATGTTAATATAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045224.1\|WP_003420072.1\|2457973_2459368_-\|NADPH-dependent-glutamate-synthase	unknown	unknown	gnl\|CDD\|183780
NZ_CP045224.1\|WP_003420054.1\|2469742_2470417_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213222
NZ_CP045224.1\|WP_003420045.1\|2476591_2477473_+\|polysaccharide-deacetylase	unknown	unknown	gnl\|CDD\|200569
NZ_CP045224.1\|WP_029158134.1\|2454490_2455237_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
NZ_CP045224.1\|WP_003420078.1\|2452610_2454491_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376899
NZ_CP045224.1\|WP_003420080.1\|2451100_2452492_-\|MATE-family-efflux-transporter	unknown	unknown	gnl\|CDD\|240548
NZ_CP045224.1\|WP_003420065.1\|2461865_2463479_-\|gamma-glutamyltransferase	unknown	unknown	gnl\|CDD\|223482
NZ_CP045224.1\|WP_003420055.1\|2468502_2469735_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|223914
NZ_CP045224.1\|WP_009905491.1\|2459367_2460261_-\|sulfide/dihydroorotate-dehydrogenase-like-FAD/NAD-binding-protein	unknown	unknown	gnl\|CDD\|235747
NZ_CP045224.1\|WP_003420052.1\|2470419_2471652_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223650
NZ_CP045224.1\|WP_003420046.1\|2475261_2476206_-\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|223769
NZ_CP045224.1\|WP_003420048.1\|2474493_2475039_-\|NADH-peroxidase	unknown	unknown	gnl\|CDD\|153105
NZ_CP045224.1\|WP_003420061.1\|2465634_2466402_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
NZ_CP045224.1\|WP_003420049.1\|2473254_2474403_-\|DUF362-domain-containing-protein	unknown	unknown	gnl\|CDD\|224917
NZ_CP045224.1\|WP_003420051.1\|2471936_2473202_-\|dihydroorotase	unknown	unknown	gnl\|CDD\|236479
NZ_CP045224.1\|WP_003420074.1\|2455389_2457609_-\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|238923
NZ_CP045224.1\|WP_003420062.1\|2463710_2465648_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376899
NZ_CP045224.1\|WP_003420057.1\|2467387_2468392_+\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|340424
NZ_CP045224.1\|WP_003420059.1\|2466689_2467364_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_CP045224.1\|WP_003420067.1\|2460886_2461738_+\|sulfurtransferase	unknown	unknown	gnl\|CDD\|225450

Protein	Function_ID	Function_description	E-value
NZ_CP045224.1\|WP_003420072.1\|2457973_2459368_-\|NADPH-dependent-glutamate-synthase	gnl\|CDD\|183780	PRK12831, PRK12831, putative oxidoreductase; Provisional.	0
NZ_CP045224.1\|WP_003420054.1\|2469742_2470417_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	1.19086e-109
NZ_CP045224.1\|WP_003420045.1\|2476591_2477473_+\|polysaccharide-deacetylase	gnl\|CDD\|200569	cd10944, CE4_SmPgdA_like, Catalytic NodB homology domain of Streptococcus mutans polysaccharide deacetylase PgdA, Bacillus subtilis YheN, and similar proteins. This family is represented by a putative polysaccharide deacetylase PgdA from the oral pathogen Streptococcus mutans (SmPgdA) and Bacillus subtilis YheN (BsYheN), which are members of the carbohydrate esterase 4 (CE4) superfamily. SmPgdA is an extracellular metal-dependent polysaccharide deacetylase with a typical CE4 fold, with metal bound to a His-His-Asp triad. It possesses de-N-acetylase activity toward a hexamer of chitooligosaccharide N-acetylglucosamine, but not shorter chitooligosaccharides or a synthetic peptidoglycan tetrasaccharide. SmPgdA plays a role in tuning cell surface properties and in interactions with (salivary) agglutinin, an essential component of the innate immune system, most likely through deacetylation of an as-yet-unidentified polysaccharide. SmPgdA shows significant homology to the catalytic domains of peptidoglycan deacetylases from Streptococcus pneumoniae (SpPgdA) and Listeria monocytogenes (LmPgdA), both of which are involved in the bacterial defense mechanism against human mucosal lysozyme. The Bacillus subtilis genome contains six polysaccharide deacetylase gene homologs: pdaA, pdaB (previously known as ybaN), yheN, yjeA, yxkH and ylxY. The biological function of BsYheN is still unknown. This family also includes many uncharacterized polysaccharide deacetylases mainly found in bacteria.	2.82771e-75
NZ_CP045224.1\|WP_029158134.1\|2454490_2455237_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	9.5071e-102
NZ_CP045224.1\|WP_003420078.1\|2452610_2454491_-\|ABC-transporter-permease	gnl\|CDD\|376899	pfam02687, FtsX, FtsX-like permease family. This is a family of predicted permeases and hypothetical transmembrane proteins. Buchnera aphidicola LolC has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both LolC and Streptococcus cristatus TptD have been shown to require ATP. This region contains three transmembrane helices.	6.94468e-07
NZ_CP045224.1\|WP_003420080.1\|2451100_2452492_-\|MATE-family-efflux-transporter	gnl\|CDD\|240548	cd13143, MATE_MepA_like, Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Streptococcus aureus MepA and Vibrio vulnificus VmrA and functions most likely as a multidrug efflux pump.	3.39881e-140
NZ_CP045224.1\|WP_003420065.1\|2461865_2463479_-\|gamma-glutamyltransferase	gnl\|CDD\|223482	COG0405, Ggt, Gamma-glutamyltransferase [Amino acid transport and metabolism].	0
NZ_CP045224.1\|WP_003420055.1\|2468502_2469735_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|223914	COG0845, AcrA, Membrane-fusion protein [Cell envelope biogenesis, outer membrane].	7.07051e-21
NZ_CP045224.1\|WP_009905491.1\|2459367_2460261_-\|sulfide/dihydroorotate-dehydrogenase-like-FAD/NAD-binding-protein	gnl\|CDD\|235747	PRK06222, PRK06222, sulfide/dihydroorotate dehydrogenase-like FAD/NAD-binding protein.	0
NZ_CP045224.1\|WP_003420052.1\|2470419_2471652_+\|ABC-transporter-permease	gnl\|CDD\|223650	COG0577, SalY, ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms].	6.78715e-36
NZ_CP045224.1\|WP_003420046.1\|2475261_2476206_-\|DMT-family-transporter	gnl\|CDD\|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	2.55984e-12
NZ_CP045224.1\|WP_003420048.1\|2474493_2475039_-\|NADH-peroxidase	gnl\|CDD\|153105	cd01046, Rubrerythrin_like, rubrerythrin-like, diiron-binding domain. Rubrerythrin-like domain, similar to rubrerythrin, a nonheme iron binding domain found in many air-sensitive bacteria and archaea, and member of a broad superfamily of ferritin-like diiron-carboxylate proteins. Rubrerythrin is thought to reduce hydrogen peroxide as part of an oxidative stress protection system. The rubrerythrin protein has two domains, a binuclear metal center located within a four-helix bundle of the rubrerythrin domain, and a rubredoxin domain. The Rubrerythrin-like domains in this CD are singular domains (no C-terminus rubredoxin domain) and are phylogenetically distinct from rubrerythrin domains of rubrerythrin-rubredoxin proteins.	9.79702e-55
NZ_CP045224.1\|WP_003420061.1\|2465634_2466402_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	3.19794e-102
NZ_CP045224.1\|WP_003420049.1\|2473254_2474403_-\|DUF362-domain-containing-protein	gnl\|CDD\|224917	COG2006, COG2006, Uncharacterized conserved protein [Function unknown].	3.03391e-76
NZ_CP045224.1\|WP_003420051.1\|2471936_2473202_-\|dihydroorotase	gnl\|CDD\|236479	PRK09357, pyrC, dihydroorotase; Validated.	0
NZ_CP045224.1\|WP_003420074.1\|2455389_2457609_-\|EAL-domain-containing-protein	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	1.83458e-98
NZ_CP045224.1\|WP_003420062.1\|2463710_2465648_-\|ABC-transporter-permease	gnl\|CDD\|376899	pfam02687, FtsX, FtsX-like permease family. This is a family of predicted permeases and hypothetical transmembrane proteins. Buchnera aphidicola LolC has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both LolC and Streptococcus cristatus TptD have been shown to require ATP. This region contains three transmembrane helices.	1.73546e-05
NZ_CP045224.1\|WP_003420057.1\|2467387_2468392_+\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|340424	cd16948, HATPase_BceS-YxdK-YvcQ-like, Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ. This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.	3.55793e-54
NZ_CP045224.1\|WP_003420059.1\|2466689_2467364_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	6.598e-73
NZ_CP045224.1\|WP_003420067.1\|2460886_2461738_+\|sulfurtransferase	gnl\|CDD\|225450	COG2897, SseA, Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism].	1.23875e-68

>NZ_CP045224.1|WP_003420061.1|2465634_2466402_-|ABC-transporter-ATP-binding-protein
MEEILSVENIKKEYGRKGSKHEALRGITFKVYKGEFVGIMGSSGAGKSTLLNIISTIDLPSSGDIYINGKNTIKMKQNELADFRRDNLGFVFQDSNLLDTLTIKENIMLPLSLKNERVSVIENRINEISRELNIESILDKYPSEVSGGQKQRGAVCRAIATKPSLVLADEPTGALDSKSARDLLNCLLKLNKDSNKTILMVTHDAISASFCNRILFIKDGIIFTEIVKGESNREFYNKIVNTVSLIGGVNKNDFI
>NZ_CP045224.1|WP_003420062.1|2463710_2465648_-|ABC-transporter-permease
MTLFRIAMKNVKNSFFNYLMYFISIVFSVFIFFSFKSIEYNKALSSLGEKTRMSINTSSILIVAFVFLFIYYSNSFFFNRRSREVGTYSLLGMRKNQIGKIFLYETFLMGIVAILIGIFLGLLFSKLMTMMLVKLMNEMIVVNMNLSIKALVQTLAVFLTIFIVIGIRNTIVIRNKRIIELFNKPPEKCRFKKFIKLKGALGVLLITISYLMSISYFIAENIMFSVFILVTIIPGTFLFFSSVMYMIIDAVKKRKGFYYKGQNLIAFSELGFKLKSNSSVLAIIAILIATSVTILGFTISLYYDIDRNISENYKYSYTINLGNSHVNNKIDKLLDKYKKDNKIIFDKTIELIDKDINLEMYYKNGNSYIEDRTSVDIIRESDFKKLRQYQNNNYEELISKESVYYVSDSYKKILFKDFEIEKINLHFKDTSECDINLFTVQKTILEPEINSQATFDLIVVKDKVFNQLKLHGDSRLIRLIDIKNEKKELNLTLKLKNIVSENMEFTYPFNFTSSIESYDNLIKLSGLMLFIGIFLSVVFLLCTGSIILFKQLSNIYDDRERYIMLTKLGANNKDIEKIISKQLKVIFLMPLVVGTVHNLFAMSIVQKFIPRSLLVPIIITLVIYFIGYFIYYFLTLKYALNMITE
>NZ_CP045224.1|WP_003420065.1|2461865_2463479_-|gamma-glutamyltransferase
MKFNAYQHKYSSIRNVVYAKNGAVATSTPLASQAGLEILKKGGNAVDAAVATAATLAVVEPTSNGIGGDAYALVWIEEEKRLYGLNSSGFAPENMELKNYNNMKEMPKYGFGAVTVPGIPAAWSELNKKYGKLSLIECLSPAINYAREGYVVSPNVAKVWKKSYELYEKELIGEEFKPWFDTFSKDGKAPEAGDIFICEEQASTLEEIANTQAESFYRGRLADKIDEYSRKFNGAIRKSDLECFYPTWVEPISTEYKGYKIFEIPPNGHGITVLMALNILKELKLEGNIENVEDIHKIIESLKLAFADSKTYVTDIEHMKVKIQELLSQEYAKKRSLLIDNKEALYPTAGEPYCGGTVYLCTADKDGNMVSYIQSNYINFGSGIVIPRTGIALHSRGNNFNLDPEHHNVVKPFKKPYHTIIPGFLGKEDKAIGPFGVMGAFMQPQGHIQVLTNMIDFGLNPQEALDAPRWQWIKGKEIEVESEMPKHIIDSLIEKGHEIKVIHDTVDMGRGQIIFKTEQESYICGTESRCDGHIAVY
>NZ_CP045224.1|WP_003420067.1|2460886_2461738_+|sulfurtransferase
MKNIISAKELISKLEQNDNLVVIDCRFDLINRTYGIDSYKKGHIKGSFILDIDKDLSSPTKEHGGKNPLQDPLILKEKLEKMGVDNNTTIVTYDDGDLNGACRLFFQLKHLGLKNVYVLDGGITSFVKEGGELEKKVNVPSCTGKEIKPNINNDLVVPMEYVKSKLYKKDTVIIDCRANERYQGLVEPAYSKAGHIPSAKNYFCKDLIKSDFENGSLKDIEFLKKFFKDLNNYDEVILSCGSGISACVNSLALRELDIPHKIYIGSFSDWISYDDNEIKTGQE
>NZ_CP045224.1|WP_009905491.1|2459367_2460261_-|sulfide/dihydroorotate-dehydrogenase-like-FAD/NAD-binding-protein
MSNKIVSKRQLTDSIYLMEIEAPRVAKSSQPGQFIIIKNDEKGERIPLTIADYDREKGTVTIVFQTVGASTKKLAMFEENDFVMDFVGPLGQASEFIHEDIEELKNKKILFVAGGVGSAPVYPQVKWFKEHGLDVDVIIGARTKELIILEDDMKKVAKNVYVSTDDGTYGFNGRVTDLLKDLVDNQGKKYDQAIVIGPMIMMKFMCQLTKELNIPTIVSLNTIMIDGTGMCGGCRVSVGNETKFACVDGPEFDGHLVDFDQAMRRQSMYKTQEGRAMLKLEEGDSHHHSNCGCGGNK
>NZ_CP045224.1|WP_003420072.1|2457973_2459368_-|NADPH-dependent-glutamate-synthase
MDAKKVKVPVREQEPAVRATNFDEVCLGYNKEEAMAEANRCLACKKPKCVGGCPVGIDIPGFITKIKEDDIEGAAKVIAKSSSLPAVCGRVCPQESQCEGVCILGIKSDAVSIGKLERFVADWSKENDINLSDTEPKKNQKVAVIGSGPAGLACAGDLAKKGYDVTIFEAMHEPGGVLTYGIPEFRLPKQAVVQPEIDNIRKLGVKIETNVIVGKTITVDELIEDEGFEAIFIGSGAGLPMFMNIPGENANGVFSANEFLTRVNLMKAYRDDYDTPISSGKKVAVVGGGNVAMDAARTALRLGSESYIVYRRSEKELPARAEEVHHAKEEGIIFNTLTNPKEILVDENGYVKGMVCIRMELGEPDDSGRRRPIEIEGSEFVLDVDTVIMSLGTSPNPLISSTTKSLDINKKRCLITDENGQTSKEGVFAGGDAVTGAATVISAMGAGKTAAASIDEYLKAKVNA
>NZ_CP045224.1|WP_003420074.1|2455389_2457609_-|EAL-domain-containing-protein
MKKREKVFDGLVFKHILILLILLVLIDLTSTIIYASNSMEITSRNMIETSKRELENYLEINISLLKALSKDDRFSDSETSLIEKGKLLRPYQKEYNLFMIGITDTKGNTSSTYREKVGSIKDRPSFEKAIKTKQVVVSDIEVSNVTGDKVFIIYVPIIKNNEMIGTIFASFYFQDVNNLISRSNLDDSIKFLMIDKNYTIISHPNKKYVNDKSKILDLEGNIIGTTKSEILKNINEKCQGKFLYWDNWRLYNVKYTNIKWTNWTLVSKCNIFKNFQSLIVNFMIKLYFYIVIFMILWKLSNAKLIEQLKKLAYYDSLSGIKNKEKFRKDSMYILKNYYQDNFYLVQLDVNKFKYINEMFGYAEGNKILIHISQVLNNNTNKYEICARMDNDHFILLIACSTEDELLNRLSKINKEICNLSTTNSSKYKIVMSSGIYKINKKDDIKKIDLLIDRANIAAKSKKEKYEHSYSFFNEETRNRLYKEKRLEDNMNKALEKGEFIVYYQPKYSLNDVNEIEGAEALIRWNSPEFGFISPIDFVPLFEKNGFIVNIDMFVFEEVCKTLNKWINKGYTPVPISVNMSRVHLYRDNFIENITDLISKYNISPEFIELELTESVVFDNLNILIDIMKKIKEIGFLISMDDFGSGYSSLNLLKDLSFDILKLDRGFLIETTDTKRGKIIISKIVEMAKAIDIKVICEGVETYEQVEFLREIGCDKVQGYLFAKPMVLDEFEKHLNFKFD
>NZ_CP045224.1|WP_029158134.1|2454490_2455237_-|ABC-transporter-ATP-binding-protein
MNILSIRNISKTYCGNIPFKALDKVSLNIDKGEFVSVMGPSGSGKSTLLNIISTVDRQSEGEVILDGYDISKLEGEKLAEFRRKQLGFVFQDFNLIDTLTVGENIMLPLTLEGASIKDINIQTRNISKFLGIDKILDRKTYEISGGQAQRCAIARAIINKPAILLADEPTGNLDSKSTDDVLKLFTKINIEQNVTTLMVTHEAYSASYSDRVIFIKDGCIYTEIKKSESSNSFYSDILAVLSQIGGVR
>NZ_CP045224.1|WP_003420078.1|2452610_2454491_-|ABC-transporter-permease
MDFKKFAYNNIVRNFRAYLAYFLSSVFSIMIFFVFAVSMFHPIIMKSGIQSGFTAFMALMTSELIILGFSLLFILYSLGNFLKYRLKDFGVLMIIGMSNRQLKKLILIENLIIGFLAVMLGILLGLSISKLFLLYLSKLFYMNLTELYFPVKAILLTVVSFMILFLITGPMSLKLLNKKSILELLLGTKKPKKEIKSSKLFGIAGIVCLILGYAMILFGNKLKINGGMYTTTLLITLGIFLFFSQFTILILKYLKNKEKFYKNKVNMLLISNLMYKLKDNTRLLFLITILLSATLVAFTTTSTLVSSQGESSKNNFPMVYSYFSEHNNEKEYEELQKIRDTIKRYDYKELSFPILQYNREVLLNVKDYNKLSKELGLDKISSKLRKYEGIIIPSSNSQEHINSLKELRNYSIKNLNIKIKKSTNKIIFPTGLFSKVVVISDDLYNEVKGEFSKMNFHGFDYKNWQNSAKITENLKVKHFNLDREYNRSYFLTLPDMYLVELQQSKILQFMGVFIGVILFIAVFSFLYFRLYTDEMEDNVKYKKLSKIGLSFKNMNKIVSIEIGTLFFIPYFIAIINSIISLLFLNQVLNNSFNLENLGILLLISSIYSLYFYLLKKFYTRKVWFFD
>NZ_CP045224.1|WP_003420080.1|2451100_2452492_-|MATE-family-efflux-transporter
MENQQLLGTERISKLLLKYSIPAIIGMLVNSLYNVVDRIFIGNIPGVGPLAITGLGVTMPIMTIILAFGMLIGIGTTTTISIKLGQGKVEEARKLIGNAMTLSVITGIIIMILGILFANKILTLFGASENTLIYAKSYINIILLGTVVNLLSFSLNHSIRADGSPKISAGIMIVGCLTNIVLDWILIFGFNLGIQGAAIATVTSQALTAVLTIGYYISGKSNLRFSKSNLKLDTKLIKAVFAIGMSPFAMQLAASLVQVISNIALKTHGGDLAIGAMATISSIAMVFLMPIFGINQGAQPIIGFNYGAEKYDRVKKAYLGSLAVATIILCMGMVVIMLFPEAIIGIFNKDPELMNISVNGLRIYLLMLPIVGLSVTGTNFIQSIGKAKMAMLLSLLRQVILLIPAVLILPTFLGLQGVWTAQPVSDFIATVITGIVVFRELKRYTPKTEKLNENERLNEITTE
>NZ_CP045224.1|WP_003420059.1|2466689_2467364_+|response-regulator-transcription-factor
MFKIMVVEDDVSLKNIIAECLTKWGHNVHQIENLENIIEEFKNYKPQLVLLDINLPFYDGFYWCNEIRKISKVPIIFISSRNSNMDVIMGVNLGADDYIQKPFSIDVLVAKVNALLRRTYNFVDNNSNQIIHNGVTLDLSTATINYEDNTIELTKNEIKILHELMKYKGQIVSRNKLMKKLWDNDWFVDDNTLTVNVNRIRSKLNEIGLEDFIETKRGLGYIIN
>NZ_CP045224.1|WP_003420057.1|2467387_2468392_+|HAMP-domain-containing-histidine-kinase
MSFKDFLKDKLGFLVYNFTFLIFTIAVIIFSPVDVFLIDTILYILVINVVFLFLYLFISYIKKNKFLDKIKNDTFKININTTELAKCKNEEKIYLNIIKNHQYQCNNIINKNIKKFEENKEILNMWVHDVKIPIAIIKLTLEQNENLIDEKISDDIDSEIFRIENSVEKILYLSRLEDFHKDFLIQEVNIEKIIRNIIKKYSKYFISKKIILNLNNLNFKVLSDEKWLYFIFEQLLSNSLKYSSLGDNISIYCKRSKNYLQLRVEDTGCGIKKEDLNRIFNKGFTGNNGRNNSKSTGLGLYLVKELCDKLGHKIAVDSEYNQYTKFTITFKCDL
>NZ_CP045224.1|WP_003420055.1|2468502_2469735_+|efflux-RND-transporter-periplasmic-adaptor-subunit
MSFLKKFKNKRFRNNSFKSNNFRSSSFGSSGFNSKNKGFKNNPFKNKRFKIYAGIAVIILLILGVLAYVDSKNTKLQANENFIETYTIPENEKIFINGMVVPKQTKDFNISGDYELSDVNVTNGQKVNQGDLLFTAKNPTIIAEIDSLKSQLSQYKKQKISLSDIAENRDAIASINAQITTLNSQIASLDKKAYDRVTAPFDGTVYLNDQTGNPDQPVSFMTIQGLEFYMKGQASEQDLPKMKIDQMVNILVFSTDQKLTGRISFISDKPSTPNTEMGAQQNTLSYYDINIAFDNQEGLVNGFHLQASLEVSNSSFKIPASCVLKDKKHSYVFKDLDGILKKQIVDVASQNDDFAVVRGGLEQGDIIIKHPTKEMKEGDPVQGDGVTAGSNNNGDTTPNKKVEEVNMDVN
>NZ_CP045224.1|WP_003420054.1|2469742_2470417_+|ABC-transporter-ATP-binding-protein
MLIKLENIQKYYKVGKDELHVLKSLNLEIESGEFVMIMGKSGSGKTTLLNILGFLDVFDEGRYIFDGTDVTNLSENERSVFRNINIGFVFQQFNLIETLNVYQNVELPLIYNKSLKKSNREEIVKDKLSSVGLLDKLKQKPLQLSGGQQQRVAIARCLANDPQIIFADEPTGALDSETSREIMELLTRLNKQGKTIIMVTHDQDLTKYATKVIRLKDGVFTSEV
>NZ_CP045224.1|WP_003420052.1|2470419_2471652_+|ABC-transporter-permease
MSLLKNSLANLKGHKLRVFVALLWIIIGITSVILVSSIGNGFQKEIKKSVNNVNPNKTTISFESADNTGLTDDMSIFLKPFNAKDLEELSFVEGVERIAPSRDGFNLDSVYSSQASFDKKTTYVDVGPVKKDSKINLICGRDFSLDDEKRKVILLTLQSTSEIFENPEDALGHGININGTIFEIIGVLDDSQQNQAGGFFGGYQDMQFTTSLIPKKAFDTLMSQNSYSNEIYQLDLVSSKGYNVNEVANNVISKLYEMHPGINGSYTTPDPTEQTAYLESINSNVNKYVSIITVVAMFVGGIGVMNIMYVSVMERQREIGIRRAIGAKPRSILFQFLVEAVFITVCGGILGTIVGFAATNYVSKYIGFEAIPSLNSLFYAIIATILTGVVFGLIPAFKASKLDPIKAIYK
>NZ_CP045224.1|WP_003420051.1|2471936_2473202_-|dihydroorotase
MILIKNGRVIDPKSQRDENIDLIIKENKIYKIGKFDESDEYEKIIDASGNVVAPGLVDVHVHFRDPGFTYKEDIESGAKSAARGGFTTVICMANTNPIVDNEDTFNYVKEKSKNACINVLQAAAITKGFEGKELVDMEALKKAGVPGFTDDGLPLMDSNLIMEAMVKAKELDVPLSFHEEDPSLVGNPGVNAGKIASELGLKGASSVAEDVMVARDCMLALKTGAKVDIQHISSGVSVDMVRFAKYLGANVVAEASPHHFTLTEEDVLEFGTNAKMNPPLRSKWDRDKIIEGLNDGTIEIIATDHAPHSREEKDREFIKAPSGIIGLETSLALGITNLVHKNHLSMMQLIEKMSTNPAKLYNLNTGFIEEGAVADIVIFNPEEEWTVESFVSKADNSPFKGKSLYGKINYTICNGKIVYNA
>NZ_CP045224.1|WP_003420049.1|2473254_2474403_-|DUF362-domain-containing-protein
MKSVSVRSCKTYNYEEVRLSIEKNLEDIGGIDKFVKKGSKVLIKPNLLMKKKPEEATTTHPMVVKVVCEKLLELNCDITIADSPGGPYNQSSLKSIYKASGIEEVANELGIKLNYDVSDVKVHSEKAHVLKYMDIIKPVVDSDYIINLCKLKTHIMATFTGGTKNLYGCIAGLKKAEIHYRFPTEELFCENVLLDICDYIKPTLTIMDGIVGMEGDGPSAGTTREIGVLLASQNPYAIDVVACKIISLIPNRVATIRGAIKRGYIREDFSDIEILGEDINDLIIKNYKVPNVSKDLRLFSVKLPKFLNEPISKLITPKPVVRFQDCIKCGKCKEACPAATIEIGTKGAIIDLSKCIRCYCCHELCPKKAIDVKRNFVFKYVK
>NZ_CP045224.1|WP_003420048.1|2474493_2475039_-|NADH-peroxidase
MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEMVWADEHRIGVAQGVDAEIIEGLRANFTGECTEVGMYLAMSRQADREGYPEVAEAYKRIAFEEAEHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKRAKELGLDAIHDTVHEMCKDEARHGKAFLGLLNRYFGK
>NZ_CP045224.1|WP_003420046.1|2475261_2476206_-|DMT-family-transporter
MQKNKKEGALLKKYFGEIGLIFIAIIWGSGFVATQFALDGGLTPLQIITLRFFLAAIIMNLLFFKQIRANMGKKLLKAGGILGIFLFLAFTVQTIGLMYTTPSKNAFITAANVVIVPFIGFILYRRKLDKIGIISSLVALIGIGILSLEADFSINFGDFLTLICSFGFAFHIFFTSEFAKDNNPMALTAIQFTVAFLMSVIVQAFAGQLKMEAELSGYMGTMYLAVFSTTIGFLFQTICQKRVDGTRTAIILSTEAVFGTIFSIIILKELITAKLVIGSILIFVAIITAETKLSFLKSKKVKLKDSEESSLESI
>NZ_CP045224.1|WP_003420045.1|2476591_2477473_+|polysaccharide-deacetylase
MVKKRKKKTVALTIIVVIVIGIFSMAWADMSRKKEMKETQERLKAERLEKERIEKEKNEPIIGAKKEAIKEYGYDAKIVWDKLNKYDYSNNGEKIVFLTFDDGPSTTNTPQVLDILKRHGVRGTFFIKGDSLERKGANEILKRTFDEGNAIAHHSYTHDYKKLYPGRSLNLDTFVNELNKTDEAMKKVLGKNFSSNVVRCPGGYMSWKNMEPLGNYLKEKNMASIDWNALNADAEGKKKNAQELFEHAKKSSEGKEMVVLLMHDTYGKQETVNALDQIITYFKDNGYQFKILI

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Crispr_ID: NZ_CP045224_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045224_12

2802314-2802940

Orphan

I-A

Consensus_repeat	Method
GTTTTATATTAACTAAGTGGTATGTAAAG	PILER-CR
CTTTACATACCACTTAGTTAATATAAAAC	CRISPRCasFinder
CTTTACATACCACTTAGTTAATATAAAAC	CRT

9 spacers

The CRISPR arrays of NZ_CP045224_12

>merge|NZ_CP045224|12|2802314-2802940|PILER-CR,CRISPRCasFinder,CRT
CTTTACATACCACTTAGTTAATATAAAACAATATTTATCTTGTTTCAATGCTTCTATACATATTTCCTTTACATACCACTTAGTTAATATAAAACAAGATAAAAGTGAAATATCTGAATATATAGAAAAACTCTTTACATACCACTTAGTTAATATAAAACCACCATTAATTAAGGGGCAATTTAGCCTTGCAAATTTCTTTACATACCACTTAATTAATATAAAACTGTCCCAAAATAGCATCATTACTTTAAGTTCAGCATTCTTTACATACCACTTAGTTAATATAAAACCAATATCCATTTCTCCTTTTCCAGCAATATTAAATTTCTTTACATACCACTTAGTTAATATAAAACGAGTGTATGCTGAATATGGTTTAAGAAGTCCTGACATACTTTACATACCACTTAGTTAATATAAAACGTCTTTTCAATCTGTTCAACTACCTTAGGTTCATTCAGCTTTACATACCACTTAGTTAATATAAAACCTTATACTTCCGTTATTAAACATCATATCTGCTATTATCTTTACATACCACTTAGTTAATATAAAACGGCAATCCCTTAACCATAGCCAACTATTTAATTTTGAGCTTTACATACCACTTAGTTAATATAAAAC

>NZ_CP045224|12|6|2802314-2802940|PILER-CR
CTTTACATACCACTTAGTTAATATAAAAC	AATATTTATCTTGTTTCAATGCTTCTATACATATTTC
CTTTACATACCACTTAGTTAATATAAAAC	AAGATAAAAGTGAAATATCTGAATATATAGAAAAACT
CTTTACATACCACTTAGTTAATATAAAAC	CACCATTAATTAAGGGGCAATTTAGCCTTGCAAATTT
CTTTACATACCACTTAATTAATATAAAAC	TGTCCCAAAATAGCATCATTACTTTAAGTTCAGCATT
CTTTACATACCACTTAGTTAATATAAAAC	CAATATCCATTTCTCCTTTTCCAGCAATATTAAATTT
CTTTACATACCACTTAGTTAATATAAAAC	GAGTGTATGCTGAATATGGTTTAAGAAGTCCTGACATA
CTTTACATACCACTTAGTTAATATAAAAC	GTCTTTTCAATCTGTTCAACTACCTTAGGTTCATTCAG
CTTTACATACCACTTAGTTAATATAAAAC	CTTATACTTCCGTTATTAAACATCATATCTGCTATTAT
CTTTACATACCACTTAGTTAATATAAAAC	GGCAATCCCTTAACCATAGCCAACTATTTAATTTTGAG
CTTTACATACCACTTAGTTAATATAAAAC

>NZ_CP045224|12|10|2802314-2802940|CRISPRCasFinder
CTTTACATACCACTTAGTTAATATAAAAC	AATATTTATCTTGTTTCAATGCTTCTATACATATTTC
CTTTACATACCACTTAGTTAATATAAAAC	AAGATAAAAGTGAAATATCTGAATATATAGAAAAACT
CTTTACATACCACTTAGTTAATATAAAAC	CACCATTAATTAAGGGGCAATTTAGCCTTGCAAATTT
CTTTACATACCACTTAATTAATATAAAAC	TGTCCCAAAATAGCATCATTACTTTAAGTTCAGCATT
CTTTACATACCACTTAGTTAATATAAAAC	CAATATCCATTTCTCCTTTTCCAGCAATATTAAATTT
CTTTACATACCACTTAGTTAATATAAAAC	GAGTGTATGCTGAATATGGTTTAAGAAGTCCTGACATA
CTTTACATACCACTTAGTTAATATAAAAC	GTCTTTTCAATCTGTTCAACTACCTTAGGTTCATTCAG
CTTTACATACCACTTAGTTAATATAAAAC	CTTATACTTCCGTTATTAAACATCATATCTGCTATTAT
CTTTACATACCACTTAGTTAATATAAAAC	GGCAATCCCTTAACCATAGCCAACTATTTAATTTTGAG
CTTTACATACCACTTAGTTAATATAAAAC

>NZ_CP045224|12|8|2802314-2802940|CRT
CTTTACATACCACTTAGTTAATATAAAAC	AATATTTATCTTGTTTCAATGCTTCTATACATATTTC
CTTTACATACCACTTAGTTAATATAAAAC	AAGATAAAAGTGAAATATCTGAATATATAGAAAAACT
CTTTACATACCACTTAGTTAATATAAAAC	CACCATTAATTAAGGGGCAATTTAGCCTTGCAAATTT
CTTTACATACCACTTAATTAATATAAAAC	TGTCCCAAAATAGCATCATTACTTTAAGTTCAGCATT
CTTTACATACCACTTAGTTAATATAAAAC	CAATATCCATTTCTCCTTTTCCAGCAATATTAAATTT
CTTTACATACCACTTAGTTAATATAAAAC	GAGTGTATGCTGAATATGGTTTAAGAAGTCCTGACATA
CTTTACATACCACTTAGTTAATATAAAAC	GTCTTTTCAATCTGTTCAACTACCTTAGGTTCATTCAG
CTTTACATACCACTTAGTTAATATAAAAC	CTTATACTTCCGTTATTAAACATCATATCTGCTATTAT
CTTTACATACCACTTAGTTAATATAAAAC	GGCAATCCCTTAACCATAGCCAACTATTTAATTTTGAG
CTTTACATACCACTTAGTTAATATAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045224.1\|WP_003419282.1\|2798175_2798685_-\|glycopeptide-resistance-protein-VanZ1	unknown	unknown	gnl\|CDD\|377417
NZ_CP045224.1\|WP_009905375.1\|2796034_2796397_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_003419276.1\|2799708_2800146_+\|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224759
NZ_CP045224.1\|WP_003419254.1\|2807541_2807826_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|180266
NZ_CP045224.1\|WP_003419270.1\|2801671_2801923_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_003419258.1\|2805007_2805820_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_009905368.1\|2813031_2814357_-\|pyrimidine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|274244
NZ_CP045224.1\|WP_003419256.1\|2806001_2807516_+\|recombinase-family-protein	unknown	unknown	gnl\|CDD\|238206
NZ_CP045224.1\|WP_003419264.1\|2803226_2803385_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_003419262.1\|2803522_2804968_-\|cell-wall-binding-repeat-containing-protein	unknown	unknown	gnl\|CDD\|380277
NZ_CP045224.1\|WP_003419268.1\|2802101_2802236_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP045224.1\|WP_003419289.1\|2796963_2797380_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|180266
NZ_CP045224.1\|WP_003419284.1\|2797872_2798067_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_003419240.1\|2810893_2811568_-\|O-methyltransferase	unknown	unknown	gnl\|CDD\|226607
NZ_CP045224.1\|WP_003419238.1\|2811739_2812819_-\|endolytic-transglycosylase-MltG	unknown	unknown	gnl\|CDD\|376862
NZ_CP045224.1\|WP_003419272.1\|2801318_2801507_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_003419242.1\|2809659_2810907_-\|U32-family-peptidase	unknown	unknown	gnl\|CDD\|223896
NZ_CP045224.1\|WP_003419274.1\|2800201_2800861_+\|DUF4386-family-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_003419244.1\|2807923_2809588_-\|penicillin-binding-protein-2	unknown	unknown	gnl\|CDD\|223839
NZ_CP045224.1\|WP_003419280.1\|2799220_2799385_+\|C40-family-peptidase	unknown	unknown	gnl\|CDD\|366353

Protein	Function_ID	Function_description	E-value
NZ_CP045224.1\|WP_003419282.1\|2798175_2798685_-\|glycopeptide-resistance-protein-VanZ1	gnl\|CDD\|377417	pfam04892, VanZ, VanZ like family. This family contains several examples of the VanZ protein, but also contains examples of phosphotransbutyrylases.	1.07615e-16
NZ_CP045224.1\|WP_003419276.1\|2799708_2800146_+\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224759	COG1846, MarR, Transcriptional regulators [Transcription].	8.13782e-10
NZ_CP045224.1\|WP_003419254.1\|2807541_2807826_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|180266	PRK05803, PRK05803, RNA polymerase sporulation sigma factor SigK.	1.70744e-41
NZ_CP045224.1\|WP_009905368.1\|2813031_2814357_-\|pyrimidine-nucleoside-phosphorylase	gnl\|CDD\|274244	TIGR02644, Thymidine_phosphorylase, pyrimidine-nucleoside phosphorylase. In general, members of this protein family are designated pyrimidine-nucleoside phosphorylase, enzyme family EC 2.4.2.2, as in Bacillus subtilis, and more narrowly as the enzyme family EC 2.4.2.4, thymidine phosphorylase (alternate name: pyrimidine phosphorylase), as in Escherichia coli. The set of proteins encompassed by this model is designated subfamily rather than equivalog for this reason; the protein name from this model should be used when TIGR02643 does not score above trusted cutoff. [Purines, pyrimidines, nucleosides, and nucleotides, Other].	0
NZ_CP045224.1\|WP_003419238.1\|2811739_2812819_-\|endolytic-transglycosylase-MltG	gnl\|CDD\|376862	pfam02618, YceG, YceG-like family. This family of proteins is found in bacteria. Proteins in this family are typically between 332 and 389 amino acids in length. This family was previously incorrectly annotated and names as aminodeoxychorismate lyase. The structure of YceG was solved by X-ray crystallography.	1.61962e-116
NZ_CP045224.1\|WP_003419262.1\|2803522_2804968_-\|cell-wall-binding-repeat-containing-protein	gnl\|CDD\|380277	NF033435, S-layer_Clost, S-layer protein SlpA. In Clostridiodes difficile, the S-layer protein precursor, SlpA, is one member of a large paralogous family of protein that share several cell wall-binding repeats. SlpA is cleaved into a larger and smaller protein. The S-layer protein itself is important to adhesion, and portions of it are highly variable, and then N-terminal and C-terminal are well-conserved.	6.77802e-19
NZ_CP045224.1\|WP_003419268.1\|2802101_2802236_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	0.00050055
NZ_CP045224.1\|WP_003419289.1\|2796963_2797380_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|180266	PRK05803, PRK05803, RNA polymerase sporulation sigma factor SigK.	1.7187e-70
NZ_CP045224.1\|WP_003419256.1\|2806001_2807516_+\|recombinase-family-protein	gnl\|CDD\|238206	cd00338, Ser_Recombinase, Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and serine recombinase. Serine recombinases demonstrate functional versatility and include resolvases, invertases, integrases, and transposases. Resolvases and invertases (i.e. Tn3, gamma-delta, Tn5044 resolvases, Gin and Hin invertases) in this family contain a C-terminal DNA binding domain and comprise a major phylogenic group. Also included are phage- and bacterial-encoded recombinases such as phiC31 integrase, SpoIVCA excisionase, and Tn4451 TnpX transposase. These integrases and transposases have larger C-terminal domains compared to resolvases/invertases and are referred to as large serine recombinases. Also belonging to this family are proteins with N-terminal DNA binding domains similar to IS607- and IS1535-transposases from Helicobacter and Mycobacterium.	7.13593e-29
NZ_CP045224.1\|WP_003419240.1\|2810893_2811568_-\|O-methyltransferase	gnl\|CDD\|226607	COG4122, COG4122, Predicted O-methyltransferase [General function prediction only].	4.81502e-60
NZ_CP045224.1\|WP_003419242.1\|2809659_2810907_-\|U32-family-peptidase	gnl\|CDD\|223896	COG0826, COG0826, Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones].	4.85095e-146
NZ_CP045224.1\|WP_003419244.1\|2807923_2809588_-\|penicillin-binding-protein-2	gnl\|CDD\|223839	COG0768, FtsI, Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane].	5.95773e-97
NZ_CP045224.1\|WP_003419280.1\|2799220_2799385_+\|C40-family-peptidase	gnl\|CDD\|366353	pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.	1.40608e-06

>NZ_CP045224.1|WP_003419268.1|2802101_2802236_+|helix-turn-helix-transcriptional-regulator
MFEKTNINTSVMNIIESDERPIRDDELIIFAKIFGVSINYILGL
>NZ_CP045224.1|WP_003419270.1|2801671_2801923_-|hypothetical-protein
MSSYFITRGDVMKILQQFKPYKYDKEKNIEYDEKIIANQNTEVYIVYPRISDEENRRRWEEFNEVAKEVAINIAMKKVETVES
>NZ_CP045224.1|WP_003419272.1|2801318_2801507_+|hypothetical-protein
MIGFKKRDTKYLLKIVARAHGISVAEAIVEMQTTINNARNNPDPEKQAEFIISLNTIFTKNL
>NZ_CP045224.1|WP_003419274.1|2800201_2800861_+|DUF4386-family-protein
MNIVVGVLSILSAFCIAGSMIGLMFSFGYPKIIRENPIIILKRMQNKKTMISLLFYLFGIGGFMVVQASIALRFIEQSKGEFIWSNFAYINGIIYGVLLFVGILRYTKTFPMLSNQMINKQITEKEAGQLYKVLNTYIGETMTEHVAFVFLSFMIFCNSMSLLSINYVANWIGLLGIIIAIGLFIGNLEFLGIKKLFIVNRVFSSLSAFWLLLLGICII
>NZ_CP045224.1|WP_003419276.1|2799708_2800146_+|winged-helix-turn-helix-transcriptional-regulator
MEEHEIFNTFVQILNWASERNKNSKSYGTDDKLYIAEIHTLVMIGKMPGILQKELCKEVGVTKGRMSVIIAHLQEKNLIEMRREQGNGCTIPIYLTTLGEQIYHNHNEQEMNMKIQIYQVLSKCSQEEIEKFNGILRDILEILRQ
>NZ_CP045224.1|WP_003419280.1|2799220_2799385_+|C40-family-peptidase
MFFHSTYNNGSYISHIGIYIGNNHMYHVNNPIGYADLTSAYLQQHLIGAGRIKQ
>NZ_CP045224.1|WP_003419282.1|2798175_2798685_-|glycopeptide-resistance-protein-VanZ1
MKSKKYNITKGLFIVYIIILTWIILFKLQFDVSSIETMNLRSINLVPFAGSLIINNKVDISEIILNVAIFIPFGIYICMLKEEWSFIKKVIPIFITSLAFETLQYIFALGASDITDLIGNTLGGIIGIAVFMLLSKIFKNNTIKIINILAFIVTIIVVLFLGLVIFANL
>NZ_CP045224.1|WP_003419284.1|2797872_2798067_+|hypothetical-protein
MSVIVMCSRCGKEIDKYRNKYITYYEKNTNAEIKVCINCALDLLEKTRENQELNIQEFQDTIIL
>NZ_CP045224.1|WP_003419289.1|2796963_2797380_+|sigma-70-family-RNA-polymerase-sigma-factor
MAALKSFEKPLTPEEEIEYLTKFKIENDKSAKDTLIERNMRLVAYIAKKYNNSTEDQDDLISIGTIGLIKAIETYNIDKGTRLATYASRCIENEILMNIRSNKKNKTQVSLQDPIGTDKEGNEIHTTFYMLFSTIIYI
>NZ_CP045224.1|WP_009905375.1|2796034_2796397_-|hypothetical-protein
MKIRKRGFISIECVISIAILYVAVYLVSTSLYSCYSFVSRNISDRKMLSTAKKYIEDEKYRIQNSKYELIENKIEKNYINGYEISSRVEQILDYYQCYEINIEIKNEFKKLRFNSYVTRK
>NZ_CP045224.1|WP_003419264.1|2803226_2803385_-|hypothetical-protein
MDNFLLSILASILASYIVYLISKLFRKRKKPLKAGTKSGWELDFKIKFHKFK
>NZ_CP045224.1|WP_003419262.1|2803522_2804968_-|cell-wall-binding-repeat-containing-protein
MKIKKLLTIGLSLSMFIASCHISANALDKIESIKGADKYETTGIIADKQNYTTAILINADSTMADGLSASGLAGATNAPILLTKKNNIPNATLKRLEKAKKVYIIGGENSIDKYTETVLKGKGIEIKRLQGSDRIKTSYNVAKEINSINKVNKVILTNAFKGEPDAMSAAPVAVREKAAIVLTDGKSVPFNTTGVESYVIGGTSSMNDKLVNDTNSTRLGGTDRYDTNKKIINKFYGGVKEFYIASGTDLVYALVGSTVAKNNAIVLVNNDSNKSVLKSTTKLTAIGNLSDSILQQCLNVTKNIGDSNTGRQYTVEDAANAVKKLLGVKKFYYNENYPEDEDVIFLLDENFEFSGKQFYAFGYVTENSEGDVRYCVEKNDMSKVYTYNVSGVMQVCNPDDYKKKEMISEEKAKQLALEECARKHKVGVDLLKVNIAYIDDFDDIKVYAVRIDSKPHPNQTYGWYFIDVYSGYAYKDVWNNI
>NZ_CP045224.1|WP_003419258.1|2805007_2805820_-|hypothetical-protein
MCNFKKILGLFMIIMLSVSMVACSSGGDSKDESKGKDKQFIEDLGKGLKKRWDLASKEEAGTLNLEQNEAYEKFVEVEMDAVSKYKDAEFDSPELGKLAKDYIKALEDSKEAIKYYSNDQLKFSELWEKPYNERSTILLTLVDKFGLKVDEKEFKVLKDNAQIVNEENDLKEKVNAMAKGIKFEKVKDEYDWKTYQATVENTSDLDLQDFYLDINLIDKDGVIIETQTSTSVNGTWKKGQKVRLEFSTDKDFEKIEWTPHYSANNYSITE
>NZ_CP045224.1|WP_003419256.1|2806001_2807516_+|recombinase-family-protein
MSVAIYLRKSRADEEAEKQGEFETLSRHKSTLLKLAKEQSLDVIEIKEELVSGESIIHRPKMLELLKEVEENKYDAVLVMDLDRLGRGDMKDQGIILETFKESKTKIITPRKTYDLTDEFDEEYSEFEAFMARKELKLISRRMQRGRIKSVEEGNFIGTSAPFGYDAVTTGRKERILVPNKDADIVRTIFDLYINEDMGCSKISKYLNNLGIKTATGANWYNSAITNIIKNKVYCGYIQWQKKDYKKSKNPNKIKTVKLRPKDEWIEAKGKHEPLISEITWKKAQNILKKNGHVSYGNQIKNPLAGIVICKNCGRPLVYRPYADHNYIICYHPGCNKSSRFEFIEAAILKSLEDTVKKYQLKTSDIDLDKNNKDSNIEFQKRVLKGLETELKELSKQKNKLYDLLERGIYDEDTFIERSNNISSRTEEIKDSIKTVKNRLSTVKKDNAKIIEDIKTVLSLYHDSDSLGKNKLLKSVIDKAVYYKSKEQKLDSFELMVHLKLHED
>NZ_CP045224.1|WP_003419254.1|2807541_2807826_+|sigma-70-family-RNA-polymerase-sigma-factor
MCNEISLLDILGTEANYVLDEVELKVQVGKLYEQLNKILTPREREIVQLRYGLTPYGYKTQREIAQKLDISRSYVSRIEKKALKKLEKELVQES
>NZ_CP045224.1|WP_003419244.1|2807923_2809588_-|penicillin-binding-protein-2
MSKKKTPFLKKVGKRSWCVFTIILIIYSALIYRLVDIQVLKGDKYKQSVESQSVEKVELNSGRGIIYDRNNKKLTDTSKYQVLVVEKEKLNNNYKILELIKKATKMNDLDIYKAVQEQLTRPIIQIQAKNIDKNMKKELEKNGIMIEEKTMRYSKDGLLSHTIGYIKEDDKSGQSGIEKSMDSVLRNSNEKYISAFKAGDAGNEKSLNILKGSVKTIDNKDKDRHLKTTIDYNIQRKLEQILNKEENPTAAIISEVSTGEILAMCSRPNFDQNDISKSLKGKNGEFENRVIKATYPPGSVFKMVVLFSALENGVIDENYTYNCTGKTKVGNTNEILRCNKRDGHGFQNLRQAFSNSCNPAFLDIAMKLGKEKILKSAEKLHLFEKVDIGLDEEKIREAPKNISIRNLAIGQENIEFTPLQINQMTQIMANNGTFKPLYLYKSLVDNDMNTIKTYKSSKKEELISPYVCTQVKEYMKSVSRTGTAKDLKDIEGGCGVKTGTAQSSLNKKAIDHGWITGFYPEERPKYVITVLVEGTQKGNKSATPIFKEICESIQ
>NZ_CP045224.1|WP_003419242.1|2809659_2810907_-|U32-family-peptidase
MELNKVELLAPAGDLERLKIAITYGADAVYIGGEIFGMRSAAKNFSKEDMAEGVAFAHERGKKVFVTVNIIPHNEDFLQLEDYLLELEEIGIDAVIIADPGVLSVIKKVIPNMEIHLSTQANTTNYLSANFWYEHGIKRVVVARELSFDEISEIRAKTPLDMDIEAFMHGAMCISYSGRCLISNYMTGRDANKGSCAQSCRWQYHLVEEKRPGEYFPIYEDERGTFFFNSKDLCMIEYIPELIKSGITSLKIEGRMKTAYYVATVVRAYRMAIDEFYKDPENWKFNPMWMEELKKGSHRHFTSGFYLNKPTTEDQNYQSASYVRNYDFIGIVRETEDEDGLIVVEQRNKMCVGDEIEVMGPYKETMFTKIEAMYNEEGEAIESAPHPRQIVKLKLSVKVGKDYMLRKVIEEKVEE
>NZ_CP045224.1|WP_003419240.1|2810893_2811568_-|O-methyltransferase
MSNIVNDLVEDYIRVTLKEKEGFLKDLEIYAEENSVPIIHKEVSDLLKVLLKIQKPKRVLEVGCAIGYSSIFFATIIGKDADIITVERNEKMIEKAKENIKLAGFENNITILEGDAEEKLSQVQGEFDLIFIDAAKGQYKLFFDLVIDKLKDGGLLVSDNILYKGMVAHDDFVVRRKKTIVKRMRNYLDYICNCDYLSTSLIPIGDGVALSYKESKRGDVDGIK
>NZ_CP045224.1|WP_003419238.1|2811739_2812819_-|endolytic-transglycosylase-MltG
MNFKENRLKIAALIIVILIILAGIFVSMQIGPYNKNNKKDVIIDIPNGASIGKISDILYENKLIKNELLFKLLVKVSNKAPSIKSGTYLLNQSYSNNDIISLLVSGKIYQDGIKVTIPEGATSKEIIAMLVSKNLGDKATFENLIKKPQEFYDKFPYLKEDGITSLEGFLYPETYYFNSKKQSEEDILSEMLKVFDSKYTDKFKKKQKKLNMTLQEVMEMASIIEKEAVLDKDRPIIASVFYNRLKVGMPLQSDATIQYIFEERKKIVTYDDLKIDSPYNSYKNKGLPPTPISNPGIKSIEAALYPDKTDYLYFVAKIDGGNNYSTNYQDHLKYVKEYKEARDKQSKDTKATNKENTKK
>NZ_CP045224.1|WP_009905368.1|2813031_2814357_-|pyrimidine-nucleoside-phosphorylase
MRMYDIIRKKRDNLELSKKEINYFIENYSKGDIPDYQASALLMSIYLNKMNKQETVHLTEAMMNSGDMINLSEIDGIKVDKHSTGGVGDKTTIALIPLVASCGAPVAKMSGRGLGHTGGTIDKLESIPGFSTEMEISKFINSVNKSKIAVCGQSAKVAIADKKIYALRDVTATVDNISLIASSVMSKKLASGADAIVLDVKTGDGAFMKTLEESFDLAKSMVDIGTGMNRDTIGIVTDMDEPLGFAVGNSLEVIEAIETLKGNGPKDLVELCEVLGAYMLVLSKVAYDFDDGVEKIRESIKSGDAIHKLKEFIENQGGNKDVVDDYSLFKKSKYKYPVKSTKSGYINKIKAEDVGVSAMILGAGRETKDDVLDLSVGIILEKKVGDYINEGEVLAYMYYNDEQKLSLAKDRFIDSYSIVDSKVEKNKLIYGIVTKEGIKKF

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Crispr_ID: NZ_CP045224_13

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045224_13

3182227-3182790

Orphan

Consensus_repeat	Method
TAACTGCTTCCATACATATTTCTTCTGTTTGATTTT	CRISPRCasFinder

8 spacers

The CRISPR arrays of NZ_CP045224_13

>merge|NZ_CP045224|13|3182227-3182790|CRISPRCasFinder
TTACTGCTCTTAAACAGATTGTTTCAGTTTGATTTTTTACAAATTTCAAATCAAGCCCATTTTGCCTAACTGCTTCCATACATATTTCTTCTGTTTGATTTTCTACCCATTTTAGATTATAGCTACAATGTTTAACTGCTTCCATACATATTTTTTCTGTTTGATTTTTCACTCTTGCCAATCCAAATTCACTATTTCTAACTGCTTCTATACATATTTCTTCTGTTTGTTCTTTTACATACTCCAAAGCAGTACCATTTTTTTCAACAGCTCTTAGGCACAACTCTTCTGTCTGATTTTCTATGTATTTTAAGGCTGTTCCATCTTGGTTAATAGCCAACATACAAATTTCTTCTGTTGGTTCTTCCACAAATTCTAACATTCTCCAATCTTGTTTAACCGCCTCTATACATATTTTTTCTGTCTGATTCTGAACACATTTTATTGCATTGCAATTTTGTCTAACAGCCTCTAGGCATATCTCTTCTGTTTGATTTTTTATGTATATTAAATTCAATCCATTTTTTCTTACTAGCTCTAAACATTCTTCTTCTGTTTTATTAT

>NZ_CP045224|13|11|3182227-3182790|CRISPRCasFinder
TTACTGCTCTTAAACAGATTGTTTCAGTTTGATTTT	TTACAAATTTCAAATCAAGCCCATTTTGCC
TAACTGCTTCCATACATATTTCTTCTGTTTGATTTT	CTACCCATTTTAGATTATAGCTACAATGTT
TAACTGCTTCCATACATATTTTTTCTGTTTGATTTT	TCACTCTTGCCAATCCAAATTCACTATTTC
TAACTGCTTCTATACATATTTCTTCTGTTTGTTCTT	TTACATACTCCAAAGCAGTACCATTTTTTT
CAACAGCTCTTAGGCACAACTCTTCTGTCTGATTTT	CTATGTATTTTAAGGCTGTTCCATCTTGGT
TAATAGCCAACATACAAATTTCTTCTGTTGGTTCTT	CCACAAATTCTAACATTCTCCAATCTTGTT
TAACCGCCTCTATACATATTTTTTCTGTCTGATTCT	GAACACATTTTATTGCATTGCAATTTTGTC
TAACAGCCTCTAGGCATATCTCTTCTGTTTGATTTT	TTATGTATATTAAATTCAATCCATTTTTTC
TTACTAGCTCTAAACATTCTTCTTCTGTTTTATTAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045224.1\|WP_003418469.1\|3191302_3192097_-\|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl\|CDD\|180270
NZ_CP045224.1\|WP_003418490.1\|3177416_3178112_+\|FadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225097
NZ_CP045224.1\|WP_003418494.1\|3173990_3175868_-\|PTS-glucose-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|273919
NZ_CP045224.1\|WP_003418471.1\|3189868_3191209_-\|GntP-family-permease	unknown	unknown	gnl\|CDD\|225330
NZ_CP045224.1\|WP_009905130.1\|3181207_3181696_-\|flavodoxin-family-protein	unknown	unknown	gnl\|CDD\|223788
NZ_CP045224.1\|WP_003418496.1\|3171377_3172226_-\|PRD-domain-containing-protein	unknown	unknown	gnl\|CDD\|170086
NZ_CP045224.1\|WP_009905133.1\|3170025_3170718_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_CP045224.1\|WP_003418478.1\|3183329_3183674_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_003418465.1\|3193642_3194398_-\|NAD(+)-synthase	unknown	unknown	gnl\|CDD\|238309
NZ_CP045224.1\|WP_003418475.1\|3186512_3187307_-\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	unknown	unknown	gnl\|CDD\|238847
NZ_CP045224.1\|WP_003418473.1\|3188499_3189732_-\|CoA-transferase	unknown	unknown	gnl\|CDD\|224717
NZ_CP045224.1\|WP_003418495.1\|3172253_3173660_-\|glycoside-hydrolase-family-1-protein	unknown	unknown	gnl\|CDD\|225343
NZ_CP045224.1\|WP_003418484.1\|3179216_3181145_-\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|238923
NZ_CP045224.1\|WP_003418474.1\|3187317_3188460_-\|acyl-CoA-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|173847
NZ_CP045224.1\|WP_003418467.1\|3192840_3193560_-\|YebC/PmpR-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|234640
NZ_CP045224.1\|WP_009905132.1\|3176203_3177391_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341043
NZ_CP045224.1\|WP_003418476.1\|3185479_3186502_-\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	unknown	unknown	gnl\|CDD\|224936
NZ_CP045224.1\|WP_003418488.1\|3178283_3178586_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|99911
NZ_CP045224.1\|WP_003418487.1\|3178607_3179018_-\|universal-stress-protein	unknown	unknown	gnl\|CDD\|238182
NZ_CP045224.1\|WP_003418477.1\|3184004_3185381_-\|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|226350

Protein	Function_ID	Function_description	E-value
NZ_CP045224.1\|WP_003418469.1\|3191302_3192097_-\|enoyl-CoA-hydratase/isomerase-family-protein	gnl\|CDD\|180270	PRK05809, PRK05809, short-chain-enoyl-CoA hydratase.	5.41738e-112
NZ_CP045224.1\|WP_003418490.1\|3177416_3178112_+\|FadR-family-transcriptional-regulator	gnl\|CDD\|225097	COG2186, FadR, Transcriptional regulators [Transcription].	1.67637e-27
NZ_CP045224.1\|WP_003418494.1\|3173990_3175868_-\|PTS-glucose-transporter-subunit-IIA	gnl\|CDD\|273919	TIGR01995, beta-glucosides_PTS_EIIBCA, PTS system, beta-glucoside-specific IIABC component. This model represents a family of PTS enzyme II proteins in which all three domains are found in the same polypeptide chain and which appear to have a broad specificity for beta-glucosides including salicin (beta-D-glucose-1-salicylate) and arbutin (Hydroquinone-O-beta-D-glucopyranoside). These are distinct from the closely related sucrose-specific and trehalose-specific PTS transporters.	0
NZ_CP045224.1\|WP_003418471.1\|3189868_3191209_-\|GntP-family-permease	gnl\|CDD\|225330	COG2610, GntT, H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism].	3.47169e-48
NZ_CP045224.1\|WP_009905130.1\|3181207_3181696_-\|flavodoxin-family-protein	gnl\|CDD\|223788	COG0716, FldA, Flavodoxins [Energy production and conversion].	8.57901e-12
NZ_CP045224.1\|WP_003418496.1\|3171377_3172226_-\|PRD-domain-containing-protein	gnl\|CDD\|170086	PRK09772, PRK09772, transcriptional antiterminator BglG; Provisional.	3.55303e-50
NZ_CP045224.1\|WP_009905133.1\|3170025_3170718_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	6.31987e-77
NZ_CP045224.1\|WP_003418473.1\|3188499_3189732_-\|CoA-transferase	gnl\|CDD\|224717	COG1804, CaiB, Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion].	1.13035e-105
NZ_CP045224.1\|WP_003418465.1\|3193642_3194398_-\|NAD(+)-synthase	gnl\|CDD\|238309	cd00553, NAD_synthase, NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD+ occurs via an NAD-adenylate intermediate and requires ATP and Mg2+. The intemediate is subsequently cleaved into NAD+ and AMP. In many prokaryotes, such as E. coli , NAD synthetase consists of a single domain and is strictly ammonia dependent. In contrast, eukaryotes and other prokaryotes have an additional N-terminal amidohydrolase domain that prefer glutamine, Interestingly, NAD+ synthases in these prokaryotes, can also utilize ammonia as an amide source .	6.43775e-87
NZ_CP045224.1\|WP_003418475.1\|3186512_3187307_-\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	gnl\|CDD\|238847	cd01714, ETF_beta, The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an alpha and a beta subunit which binds one molecule of FAD per dimer . A similar system also exists in some bacteria. The homologous pair of proteins (FixA/FixB) are essential for nitrogen fixation. The beta subunit protein is distantly related to and forms a heterodimer with the alpha subunit.	6.53481e-92
NZ_CP045224.1\|WP_003418495.1\|3172253_3173660_-\|glycoside-hydrolase-family-1-protein	gnl\|CDD\|225343	COG2723, BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase [Carbohydrate transport and metabolism].	0
NZ_CP045224.1\|WP_003418484.1\|3179216_3181145_-\|EAL-domain-containing-protein	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	1.17351e-82
NZ_CP045224.1\|WP_003418474.1\|3187317_3188460_-\|acyl-CoA-dehydrogenase-family-protein	gnl\|CDD\|173847	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases. Short chain acyl-CoA dehydrogenase (SCAD). SCAD is a mitochondrial beta-oxidation enzyme. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of SCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. This subgroup also contains the eukaryotic short/branched chain acyl-CoA dehydrogenase(SBCAD), the bacterial butyryl-CoA dehydorgenase(BCAD) and 2-methylbutyryl-CoA dehydrogenase, which is involved in isoleucine catabolism. These enzymes are homotetramers.	0
NZ_CP045224.1\|WP_003418467.1\|3192840_3193560_-\|YebC/PmpR-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|234640	PRK00110, PRK00110, YebC/PmpR family DNA-binding transcriptional regulator.	1.07713e-139
NZ_CP045224.1\|WP_009905132.1\|3176203_3177391_+\|MFS-transporter	gnl\|CDD\|341043	cd17490, MFS_YxlH_like, Bacillus subtilis YxlH and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Bacillus subtilis YxlH uncharacterized MFS-type transporter YxlH and similar proteins. The biological function of YxlH remains unclear. The YxlH-like subfamily belongs to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.39965e-153
NZ_CP045224.1\|WP_003418476.1\|3185479_3186502_-\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	gnl\|CDD\|224936	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion].	2.12567e-137
NZ_CP045224.1\|WP_003418488.1\|3178283_3178586_-\|hypothetical-protein	gnl\|CDD\|99911	cd05569, PTS_IIB_fructose, PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and FruB) each containing 3 domains. The FruA protein contains two tandem nonidentical IIB domains and a C-terminal IIC transmembrane domain. Both IIB domains of FruA are included in this alignment. The FruB protein (also referred to as diphosphoryl transfer protein) contains a IIA domain, a domain of unknown function, and an Hpr-like domain called FPr (fructose-inducible HPr). This familiy also includes the IIB domains of several fructose-like PTS permeases including the Frv permease encoded by the frvABXR operon, the Frw permease encoded by the frwACBD operon, the Frx permease encoded by the hrsA gene, and the Fry permease encoded by the fryABC (ypdDGH) operon. FruAB takes up exogenous fructose, releasing the 1-phosphate ester in to the cytoplasm in preparation for metabolism primarily via glycolysis. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include fructose, chitobiose/lichenan, ascorbate, lactose, galactitol, mannitol, and a sensory system with similarity to the bacterial bgl system.	2.41131e-06
NZ_CP045224.1\|WP_003418487.1\|3178607_3179018_-\|universal-stress-protein	gnl\|CDD\|238182	cd00293, USP_Like, Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae Usp reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, athough Usp lacks ATP-binding activity.	2.76739e-19
NZ_CP045224.1\|WP_003418477.1\|3184004_3185381_-\|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl\|CDD\|226350	COG3829, RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms].	2.75453e-154

>NZ_CP045224.1|WP_009905130.1|3181207_3181696_-|flavodoxin-family-protein
MKITILYQTRSGNTERVAKLIEDGAKKVDGVDVKLMRLDNIDLDYLNESKAVIFGTPTYLANTTWEVKKWFDEDSKKVNLAGKLGAVFATCDYICGGPDVAILTVVGHLMVKGMLVYSGGGSLGKPFIHLGHVHSIEGPELQDEKAIIFGERIATKAKELFN
>NZ_CP045224.1|WP_003418484.1|3179216_3181145_-|EAL-domain-containing-protein
MVWHIEYEVFSAIIVIFLMVYFFRSKFIPTLQNKIYCALLIFSFLFIISNILGSFCLNNIEKIPIFITFLLNQIYSLLLPIPAALVSFYVMAIIYQDIRYMKKRLLFLSIPLLICIILSITNPFTHILFGLSKETGYIRGCGYVATFSSFFFYAIYSALLSFKYRKAMHESKIWAIRGFLIVSIVAIILQAIFLQYLLTGTACACSLLLTYLSMQNRGLIIDDLTGVLNRQSFIQELDLNINTEQSGFIITIALDDFKFMNETFGTKNGDIALKEVGKYLVHIHDVNHVYRIGGDIFSIVVNSQLGIKPEDLIKKIEERFKKTWLVEEISFNLATSIAVVYYPENAETTEDVIVAIDFSIHEAKRSESRRVVYADASISEKIKRKHVIKNCLEEALKNDGFEVYYQPIFSNSRGRFTSAEALLRLEHKELGFIPPDEFITIAEQTGLINLIGLVVFEKVCRFIASDEFEGLKLDNIAVNLSVVQCMQKNLADDLLYLMDKYNISPTKFKLEITETVAMGSFNIIKETMERLIDLGVKFALDDFGIGYSGVSNMLSLPFSVIKLDKSLIWSMNEDSRHKLTVETIIALINKLNMKAVAEGVETIKCAEDLIAMECEYLQGYYFSKPIPEDAFKNLLKENAFTG
>NZ_CP045224.1|WP_003418487.1|3178607_3179018_-|universal-stress-protein
MNKKKILVPIDGTERSMHSLEFIKGIFKKDEVEVEIMNVKELVFIDGISLAEEIKNSENLGRRILDKAAEIMGEYDVKVHFTFGYPGDEIIRKAKEDNVDFIVMTKSTKKGLTRMIGSVTASVVKQAKCIVMIVPE
>NZ_CP045224.1|WP_003418488.1|3178283_3178586_-|hypothetical-protein
MNKKIVAVCESERSLNSLKMAANDLGFDLVYEIQENDNIKNELSIYDIEDASIVLFVTSDSIESIEKIDRFIDREFYEVDPKYIIEDAKSIVSEILIDLN
>NZ_CP045224.1|WP_003418490.1|3177416_3178112_+|FadR-family-transcriptional-regulator
MKSLNATEKIIDYIKLNILNGTFKINSKLPSERKIADLFNISRIPVRNAINILCKEGILRAVPYSSPIVEGFKKIDLFDDGEIYKNHNIQEFYVESLRARQLIESEATRLAILNATSKEIQKIKYTYLKSIEELDKVSQGLIEECYDADLQFHKEIILASHNPIFIRYYELIPKTISSNQYFGFKYRNSLKDMISHHNNIIIAFDSKDSNLGYTSMYNHLEDVIQLFQHDD
>NZ_CP045224.1|WP_009905132.1|3176203_3177391_+|MFS-transporter
MKKTSNQKLLLLSIVTFFWFSQYVYIPFQSPYLSACNVSTNMIGIIIGAYGISQCLLRLPVGVFADSINKHKIFILSGIFFAGLASLIRVFFPEGNGFLLANILSGISSSTWISYMVHYTNFFSKEHQQKATSTIILVNNLGMLIGFVMSTLFYEKLGMTALCIMSVLSSVIGTILALNIKNHNSKKMPKKISIKKYLSICKDKRLIFFSFMALIQQGIQMSTTMSFTTQILKNLGSSSTLIGLSSIFYMVCAVISSGFASTKFCTKYEPKFWIPLVFILVSAYCFLVPTIKNINIIFVLQVLPGISTGILLSYLTSESMKNVPKHQRSTAMGFFQAIYAIGMSVFPMIVGKISEYTSIRYGYFVLAIIAIVASILSYTYYKKLDLTLNYDIIQS
>NZ_CP045224.1|WP_003418494.1|3173990_3175868_-|PTS-glucose-transporter-subunit-IIA
MDYKNIAQEILLNVGGKENVNEVTHCMTRLRFKVKSASKVNKDKLSKIEGVITVVESMGQIQVVIGNKVKKVYDEVIKIVPQSNEVGKKNESEEKQGIINSILSAVAGIFTPTIPAIAGVGMIKGILSVLAMYYMNKNGVDIKETQSYIILNAMADSIFYFMPIILGYTAAKVFNANKIISMVLGATLCYPTFTALMAGEEAVRFLGLAVTKATYTSSVIPIIIAIWALSYVEKVLEKYIPEVIKIIMVPTLSLVIMLPATLFLFGPIGIYIGNIINFSYKYIYELSPALCGAFVGGLWCVLVIFGAHRALLPIGISDVAQTGRQNLLAFAGAANFSQAGAALGVFFKTKNQGLKTISMSATITALFGITEPAIYGANLRLKKPMVCAVICGAVGGAIMGMGGAYGNAFANQGVLTIPVYAEAGALGFLSYLGGCAIAFFGSAISTYLVGFEDLEESSNKENSFIKVETKDGAIDITSPVEGECIELSEVKDDVFASKAMGEGIAILPTKGVITAPTDCEVASLFPTLHAIGLKLDNGAEMLIHVGINTVELNGKYFTKHVNQGDLVKKGDKLISFDIDKIKKAGYDVTTPVIVNNTFDFGQVVSCKSSYVSTNDNIISLVLAGN
>NZ_CP045224.1|WP_003418495.1|3172253_3173660_-|glycoside-hydrolase-family-1-protein
MNTGFPKDFLWGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHLQADTKVASDFYNNYEEDIELMKELGMKTYRFSISWARIIPDGEGEINQKGIDFYNKIIDKLIECDIEPFVTLYHFDLPFTLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQPHNEQNLIVRVEERINIYDETDSWKIDKMRAQMDYNLCLAHALAVNACHEMIKESKIGAAVSSSVTYPLTSKPEDVYAARMNDNFKVYYMLDMHHYGEYPGYYMRYLEKRNIVPHMEDGDKEVLKKAKMDFIAVNYYRTNCAGAFPEDSQHPFGLREGTVDFSMYGLFKMSMNPNLEASEYGAAIDPSGLRVALNEYWQRYHLPVIITENGLGAKDILEDGKIHDDYRIDYLRSHINACRLAIEDGVEMIGYCPWSFTDLLSSSQGFNKRYGLVYINRTDHEVLDLKRIKKDSFYWYKEVIENNGIVK
>NZ_CP045224.1|WP_003418496.1|3171377_3172226_-|PRD-domain-containing-protein
MYITKVLNNSLLLARDDNDEEIILMGKGIGHNYKAGSELNKKDIEKIFVLHDENIKKSIIQLATEIDAEYFGIAQMIIAYGIEKYNLKLMNHIYLALTDHIAFAVRRFKEGIMIENHYLFEIKEFNPKEYDIGKYAITVFKEVLGLELPEEEIGNIAGHFINAQQDNPYSDRNKRSAKIVNAILQIVHYHFSIVYNKESFYYRRFVMHLKAFSQRFLANEPSKEKIDFIYEQVQKNCKEEYECVKKVGAYMYKEYSRELPRQEELYLMIHIHKILGELCENS
>NZ_CP045224.1|WP_009905133.1|3170025_3170718_-|response-regulator-transcription-factor
MNKVLIIDDDKDLCILLKKSISIEHIEANYCHSGRDGLVELSKQDYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKNDNYSKVHGLRAGADDYLTKPFEIAEFTARVLSLIRRYTRFNPKNEESQQLSFKGLLIDLDQHTVTTNGETMLLPPKEFGVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQTIKGIGYQFNTEV
>NZ_CP045224.1|WP_003418478.1|3183329_3183674_+|hypothetical-protein
MDQIKRLHELQQKSYLTKEEFEELKNNTYIEKFELRDECDNSYIYTFYTNDKCNDIKFIKSQFIVTLIKIGFLCECGGVFRQKKIVDEYDYGYNAIYKCDSCGKELDKEVENYD
>NZ_CP045224.1|WP_003418477.1|3184004_3185381_-|sigma-54-dependent-Fis-family-transcriptional-regulator
MKEQWYKDIFARVLSMTDDGFIVVNTSGVIIDINDKYCDFLGKERKDIIGHSIQSIIPNTKMLDVMRDKYCEEGAIHHYSGGNTKEKSVIVSRSYVENDNGEVVAGVAQVKFRLQSFDVAKKLMSEYMELQYYKEQFKDNCGFDKLIGENKDFIELKKTGVKASKTNFPVLLTGETGTGKEVFARAIHNNSSRSDKPMVSINCAAIPEELLESELFGYDEGAFTGAKKGGKKGKFLVANNGTIFLDEIGDMPLTMQAKLLRVLQESEIEPVGGLKTIKIDVRVISATRKNLSKMVEEGLFREDLYYRLNVINIHMMELKDRQDDILLLANYILNKLNVEYKELKVLSDKVKNCFINYTWPGNIRELQNVIKSAYAVSDDMVIMMCDLPSKMDNISRVAQCNVDSNCSIHEMVENYEKSLIIDVLRKYNWKCSKAAEVMGIHKSLLYKKIKKYEIELNN
>NZ_CP045224.1|WP_003418476.1|3185479_3186502_-|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein
MMRAKVNQGINLNDYNGVWVIGEQREGKINPVTIELIGEGRKLADQLGKELAVVIAGYEVEKEVKELLHYSVDKVYYINDPLLKDFTTDGYAISIANLIERKKPEVVLVGATSIGRDIAPRIAGKVGTGLTADCTKLEIDSTDNKLLQTRPAFGGNLMATIVCPKNRPQMSTVRPGVMAKAVRNESETGILEVVTPELTEKMIRTRLVEILPQEKKSVNLTDARIIVSGGRGLKRAEGFELIKELADKLGAEIGASRAAVDSGWIEHSHQVGQTGTTVRPELYIACGISGAIQHLAGMSDSKYIVAINKDAKAPIFSMCDYGIVGDLYEIIPEMIESLNR
>NZ_CP045224.1|WP_003418475.1|3186512_3187307_-|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein
MNIVVCLKQVPDTNEVKINKETGTLIRDGVPSIINPDDRNALEEALKMKDELGAVIKVISMGPPQAKSALKEALAMGADEAYLISDRAFGGSDTWATSTIIAAAIEKVGKYDVIFCGRQAIDGDTAQVGPEVAEFLGIPQVTYAKEVKVQDDKLLVTRYTETGDYLIEAKMPVLLTAIKELNNPRYPSVKGILEAYNNGDAKINVLTLADLDVDTTQIGLKGSPTNVYKSFVPVKDKHNEIIEGINKKEKAEKLIEILFDLKLV
>NZ_CP045224.1|WP_003418474.1|3187317_3188460_-|acyl-CoA-dehydrogenase-family-protein
MDFRLTEAQLMLQRVAKEFAENEIAPIAAETDKTGIFPRELFSKMAKIGFNGIGTPVEYSGSGGADIEKVIVVTEIAKKCAASAAILSIHTIYAQAILKFGTEEQKKKYLPMMAEGGCVGAFALTEPNAGSDAARAATTAIIDEETDEYVLNGTKCFISGGGQAESLIIFALTDPSKGIKGMSAIIVDKGTPGFSIGKIEEKMGIHGSETAELIFDNCRVPKSNLLGKEGKGFNIAMTCLDGARIGVGAQAVGIAEGALEESIKYSKERVQFGKPISALQGIQWYIADMATMVESAKLLVYYAADLKARGEKHTKEAAMAKYNASHTAREVTNLALQIHGGYGYMKDYPLERMYRDAKITEIYEGTSEIHKVVISRAVLG
>NZ_CP045224.1|WP_003418473.1|3188499_3189732_-|CoA-transferase
MLNKPLEGVKVIDLTYFVAGPGTSKILADWGADVIKVEPSFGDPGRKTGATMTMPIDDYNNPFYSTYNSNKRGLSINLKSKAGIEIMDKLLSEANVFVSSYRTGALKRLGLDYESLSKKHPHLIWGQINGFGDFGPAKDNAGFDTVAFWARSGAMLDIAEKDTSPINPPIAFGDATTSCSLSGGICAALYQQAKTGKGQKVMASLFGQAIWNASSLLASTQFSDEYPKTRKNAISPVINSYRCKDGKWIFLSILEHERYFEALCRLFGREDLIKEEKFASSVESKKNATELINILDGEFAKFTQNEMVEKLTAADIAHEKIQHVNDVVTDEQAIANNYIYEHTSKNGNKTMLASTPVKFGNIEVNMTCDAPLIGEHSDEILRELGYSDSDIEALIESGIVTMNKEACEIC
>NZ_CP045224.1|WP_003418471.1|3189868_3191209_-|GntP-family-permease
MNTGVIISLVGIIIALSLLVVMVMKGINIFIIAIVCSSLVAITGSLNVYDALKVDYMTGFVGFLQANFFIFLTGTLMGKIMEITGGAKSIAKMIVRWIGKDKALLSIPIACGILAYGGVSVFVVSFAVFPIALEIFKEADLPRRFIPAALTFGCSTFAMVAPGAPQIQNIVPASTLGTDIMAGAVNGFISCAVMFVVGSTILYKMVSKEKANGGHFIAHESDVFDESEATNSKKENGPNGVIALIPLIISILIINVKINGQAIVPIEVGVFIGALLVYLLLNKYQDNAKIVGHVGDACKTTVVAICNTCAVVAFGSVVKSAVGFDFIVNAMTNIPGPPIAGAAVGTTVIAGICGSASGGLGIAAPLLGPVFLAKGVSAAALTRTMAISSAALDSLPHNGYIVTVTNGLCKETHKDAYMPIFWVTVLTPFIGTIVAVLLFTMFPGLP
>NZ_CP045224.1|WP_003418469.1|3191302_3192097_-|enoyl-CoA-hydratase/isomerase-family-protein
MESIMENLNNLKVEVKDKVCVITINRPKALNALNNDTLRELSQVIDVISENEAILGVIITGEGKVFVAGADIRQMQNYKSEEGRKYAGYAQGIFDKIEALEKTVIAAVNGYALGGGCELAMSCDIRIASEKAIFGQPEVNLGVIPCFGGTQRLSRLVGTGIAKELIFTGRQVNAEEAKSIGLINKVVPSDLLLEESIKMMNQIVEKAPIAIRYAKVVINKGIDMDLKSALELEKDIAGLTFATRDKQEGMNAFIEKRKPVFENK
>NZ_CP045224.1|WP_003418467.1|3192840_3193560_-|YebC/PmpR-family-DNA-binding-transcriptional-regulator
MGRIGNIINRKGKQDAQRAKIFTKHARAIAVAAKDGGADPEYNAALKTAIEKAKADNMPNDNIDRAIAKGAGAGAGEDYETIVYEGYGPGGVAVIVETLTDNKNRTAGNVRYYFDKNGGNLGTSGCVSFMFDKKGQILVGLGDGVSEEELMDVALEAGAEDFITEEDGYEIITTPEDFSSVRDELKAKGYEFISADVKMIPQTTTVLTEESHLKMMNKLVDMLEEDDDVQDIYHNWEVE
>NZ_CP045224.1|WP_003418465.1|3193642_3194398_-|NAD(+)-synthase
MSNIKIQIDKTVEWLINKVNEANAKGLIVGVSGGIDSAVVANLIKKAFPENSMGVIMSIKSNPQDREDALKVIEGCDIEYLDLDLIEPQSAILDMVVGNLKDKHLYREEYLKMTDANLRARVRMSTIYTIANNLGYLVVGTDNAAEIHTGYFTKFGDGGVDILPIANLTKGEVYEWAKELGVHEDLINKAPSAGLWEGQTDEDEMGTTYNMIDAVLEGRLDEVPKRDQEIIERLHRLSEHKRKTPSQPPKF

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Crispr_ID: NZ_CP045224_14

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045224_14

3936168-3936247

Orphan

Consensus_repeat	Method
TTATAATATTATCCACATTATAAACA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045224_14

>merge|NZ_CP045224|14|3936168-3936247|CRISPRCasFinder
TTATAATATTATCCACATTATAAACAGTTGATTCATATTGCTTTAACTTATTACATTAAATATTATCCACATTATAAACA

>NZ_CP045224|14|12|3936168-3936247|CRISPRCasFinder
TTATAATATTATCCACATTATAAACA	GTTGATTCATATTGCTTTAACTTATTAC
ATTAAATATTATCCACATTATAAACA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045224.1\|WP_003420710.1\|3916709_3917462_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|239470
NZ_CP045224.1\|WP_003420711.1\|3916151_3916709_-\|2-oxoacid:acceptor-oxidoreductase-family-protein	unknown	unknown	gnl\|CDD\|376567
NZ_CP045224.1\|WP_009904773.1\|3914633_3915980_-\|phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670
NZ_CP045224.1\|WP_003421107.1\|3955312_3955744_-\|50S-ribosomal-protein-L13	unknown	unknown	gnl\|CDD\|181703
NZ_CP045224.1\|WP_003421109.1\|3955863_3956595_-\|tRNA-pseudouridine(38-40)-synthase-TruA	unknown	unknown	gnl\|CDD\|234577
NZ_CP045224.1\|WP_003420701.1\|3920595_3921498_-\|phosphate-butyryltransferase	unknown	unknown	gnl\|CDD\|180267
NZ_CP045224.1\|WP_003421608.1\|3940011_3941196_+\|pyridoxal-phosphate-dependent-aminotransferase	unknown	unknown	gnl\|CDD\|235596
NZ_CP045224.1\|WP_003421607.1\|3937287_3939639_-\|anaerobic-ribonucleoside-triphosphate-reductase	unknown	unknown	gnl\|CDD\|235937
NZ_CP045224.1\|WP_003420706.1\|3918569_3918785_-\|4Fe-4S-binding-protein	unknown	unknown	gnl\|CDD\|225131
NZ_CP045224.1\|WP_003421111.1\|3956627_3957431_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	unknown	unknown	gnl\|CDD\|223692
NZ_CP045224.1\|WP_009904772.1\|3953678_3954383_-\|N-acetylmuramoyl-L-alanine-amidase-CwlD	unknown	unknown	gnl\|CDD\|274337
NZ_CP045224.1\|WP_003421605.1\|3936726_3937266_-\|anaerobic-ribonucleoside-triphosphate-reductase-activating-protein	unknown	unknown	gnl\|CDD\|274161
NZ_CP045224.1\|WP_003420704.1\|3918827_3919505_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_003420707.1\|3917461_3918541_-\|3-methyl-2-oxobutanoate-dehydrogenase-subunit-VorB	unknown	unknown	gnl\|CDD\|235942
NZ_CP045224.1\|WP_003421115.1\|3958278_3959112_-\|energy-coupling-factor-transporter-ATPase	unknown	unknown	gnl\|CDD\|275313
NZ_CP045224.1\|WP_003421113.1\|3957424_3958291_-\|energy-coupling-factor-transporter-ATPase	unknown	unknown	gnl\|CDD\|237455
NZ_CP045224.1\|WP_003421105.1\|3954891_3955284_-\|30S-ribosomal-protein-S9	unknown	unknown	gnl\|CDD\|178888
NZ_CP045224.1\|WP_003420699.1\|3921801_3922983_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227193
NZ_CP045224.1\|WP_003420702.1\|3919494_3920574_-\|butyrate-kinase	unknown	unknown	gnl\|CDD\|235099
NZ_CP045224.1\|WP_003420697.1\|3922979_3923819_-\|TIGR00159-family-protein	unknown	unknown	gnl\|CDD\|224539

Protein	Function_ID	Function_description	E-value
NZ_CP045224.1\|WP_003420710.1\|3916709_3917462_-\|MFS-transporter	gnl\|CDD\|239470	cd03375, TPP_OGFOR, Thiamine pyrophosphate (TPP family), 2-oxoglutarate ferredoxin oxidoreductase (OGFOR) subfamily, TPP-binding module; OGFOR catalyzes the oxidative decarboxylation of 2-oxo-acids, with ferredoxin acting as an electron acceptor. In the TCA cycle, OGFOR catalyzes the oxidative decarboxylation of 2-oxoglutarate to succinyl-CoA. In the reductive tricarboxylic acid cycle found in the anaerobic autotroph Hydrogenobacter thermophilus, OGFOR catalyzes the reductive carboxylation of succinyl-CoA to produce 2-oxoglutarate. Thauera aromatica OGFOR has been shown to provide reduced ferredoxin to benzoyl-CoA reductase, a key enzyme in the anaerobic metabolism of aromatic compounds. OGFOR is dependent on TPP and a divalent metal cation for activity.	1.15077e-77
NZ_CP045224.1\|WP_003420711.1\|3916151_3916709_-\|2-oxoacid:acceptor-oxidoreductase-family-protein	gnl\|CDD\|376567	pfam01558, POR, Pyruvate ferredoxin/flavodoxin oxidoreductase. This family includes a region of the large protein pyruvate-flavodoxin oxidoreductase and the whole pyruvate ferredoxin oxidoreductase gamma subunit protein. It is not known whether the gamma subunit has a catalytic or regulatory role. Pyruvate oxidoreductase (POR) catalyzes the final step in the fermentation of carbohydrates in anaerobic microorganisms. This involves the oxidative decarboxylation of pyruvate with the participation of thiamine followed by the transfer of an acetyl moiety to coenzyme A for the synthesis of acetyl-CoA. The family also includes pyruvate flavodoxin oxidoreductase as encoded by the nifJ gene in cyanobacterium which is required for growth on molecular nitrogen when iron is limited.	1.49735e-43
NZ_CP045224.1\|WP_009904773.1\|3914633_3915980_-\|phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0
NZ_CP045224.1\|WP_003421107.1\|3955312_3955744_-\|50S-ribosomal-protein-L13	gnl\|CDD\|181703	PRK09216, rplM, 50S ribosomal protein L13; Reviewed.	1.05591e-98
NZ_CP045224.1\|WP_003421109.1\|3955863_3956595_-\|tRNA-pseudouridine(38-40)-synthase-TruA	gnl\|CDD\|234577	PRK00021, truA, tRNA pseudouridine(38-40) synthase TruA.	1.99745e-131
NZ_CP045224.1\|WP_003420701.1\|3920595_3921498_-\|phosphate-butyryltransferase	gnl\|CDD\|180267	PRK05805, PRK05805, phosphate butyryltransferase; Validated.	1.26101e-179
NZ_CP045224.1\|WP_003421608.1\|3940011_3941196_+\|pyridoxal-phosphate-dependent-aminotransferase	gnl\|CDD\|235596	PRK05764, PRK05764, aspartate aminotransferase; Provisional.	7.27196e-180
NZ_CP045224.1\|WP_003421607.1\|3937287_3939639_-\|anaerobic-ribonucleoside-triphosphate-reductase	gnl\|CDD\|235937	PRK07111, PRK07111, anaerobic ribonucleoside triphosphate reductase; Provisional.	0
NZ_CP045224.1\|WP_003420706.1\|3918569_3918785_-\|4Fe-4S-binding-protein	gnl\|CDD\|225131	COG2221, DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Energy production and conversion].	6.6539e-10
NZ_CP045224.1\|WP_003421111.1\|3956627_3957431_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	8.11538e-50
NZ_CP045224.1\|WP_009904772.1\|3953678_3954383_-\|N-acetylmuramoyl-L-alanine-amidase-CwlD	gnl\|CDD\|274337	TIGR02883, spore_cwlD, N-acetylmuramoyl-L-alanine amidase CwlD. Members of this protein family are the CwlD family of N-acetylmuramoyl-L-alanine amidase. This family has been called the germination-specific N-acetylmuramoyl-L-alanine amidase. CwlD is required, along with the putative deactylase PdaA, to make muramic delta-lactam, a novel peptidoglycan constituent found only in spores. CwlD mutants show a germination defect. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan, Cellular processes, Sporulation and germination].	2.54204e-77
NZ_CP045224.1\|WP_003421605.1\|3936726_3937266_-\|anaerobic-ribonucleoside-triphosphate-reductase-activating-protein	gnl\|CDD\|274161	TIGR02491, Anaerobic_ribonucleoside-triphosphate_reductase, anaerobic ribonucleoside-triphosphate reductase activating protein. This enzyme is a member of the radical-SAM family (pfam04055) and utilizes S-adenosyl methionine, an iron-sulfur cluster and a reductant (dihydroflavodoxin) to produce a glycine-centered radical in the class III (anaerobic) ribonucleotide triphosphate reductase (NrdD, TIGR02487). The two components form an alpha-2/beta-2 heterodimer. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism, Protein fate, Protein modification and repair].	1.03956e-50
NZ_CP045224.1\|WP_003420707.1\|3917461_3918541_-\|3-methyl-2-oxobutanoate-dehydrogenase-subunit-VorB	gnl\|CDD\|235942	PRK07119, PRK07119, 2-ketoisovalerate ferredoxin reductase; Validated.	0
NZ_CP045224.1\|WP_003421115.1\|3958278_3959112_-\|energy-coupling-factor-transporter-ATPase	gnl\|CDD\|275313	TIGR04520, ECF_ATPase_1, energy-coupling factor transporter ATPase. Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate].	4.67177e-174
NZ_CP045224.1\|WP_003421113.1\|3957424_3958291_-\|energy-coupling-factor-transporter-ATPase	gnl\|CDD\|237455	PRK13637, cbiO, energy-coupling factor transporter ATPase.	0
NZ_CP045224.1\|WP_003421105.1\|3954891_3955284_-\|30S-ribosomal-protein-S9	gnl\|CDD\|178888	PRK00132, rpsI, 30S ribosomal protein S9; Reviewed.	3.31674e-84
NZ_CP045224.1\|WP_003420699.1\|3921801_3922983_-\|hypothetical-protein	gnl\|CDD\|227193	COG4856, COG4856, Uncharacterized protein conserved in bacteria [Function unknown].	2.38896e-22
NZ_CP045224.1\|WP_003420702.1\|3919494_3920574_-\|butyrate-kinase	gnl\|CDD\|235099	PRK03011, PRK03011, butyrate kinase; Provisional.	0
NZ_CP045224.1\|WP_003420697.1\|3922979_3923819_-\|TIGR00159-family-protein	gnl\|CDD\|224539	COG1624, COG1624, Uncharacterized conserved protein [Function unknown].	1.4029e-80

>NZ_CP045224.1|WP_003420697.1|3922979_3923819_-|TIGR00159-family-protein
MLDINSFLNGFFNIILRMSIYDLIDISIVAYIFYKIFMFIKDTRAEQVFKGIIFLLLATQLSNTFKLHTVYWISLKALDYGVIAALIIFQPEFRAGLEHIGRAKFNLFGKNVNTSEETLNRNIEEIVEALYSLSRQKIGALIIMERETRISDIINTGTIIDAEISRQLLINIFIPNTPLHDGAVVIRDSKVKAAACFLPLTESKDLSKDLGTRHRAGIGVSEVSDCITLIVSEETGGVSIAKAGKLYRDISRERMMNILRSNLKTNTETRSFFKGGIFK
>NZ_CP045224.1|WP_003420699.1|3921801_3922983_-|hypothetical-protein
MINRLKNNTKIKIISFLSAIALWMYVMAVVDPEETKGFEDIPVSISNMNDLKDKNLVIYPDEKLTADVYIKGSLSKVQSVKKEDIHVHGTIEDPIQGQKEVYLKANIPQGVTIEFKHDVLVVNLEKNIKEKRDIKVEVSGNSKKNINKIELSKEFVDVSGPRTLVKEVKSVRANLDVGNETDDFSKKLQLIPLNSDGTKVEGVTLSSSFVTAKIELLKEKIVPIRVNLNDNKDNDALKNYKLSKEQVTIKGKKEDIDKINYIKTKPIDLADLANGEEKEVSLEVPEGITLEGASITIKLNDTKQLSAEFLYSAGDIELRNIPTNMDNPSVISDVDIKVVVESTEDLSKLNKKDISLYIDLSQGPEEDSKYKIKYETTYQFKKINIEPNIVEVE
>NZ_CP045224.1|WP_003420701.1|3920595_3921498_-|phosphate-butyryltransferase
MRSFEEVIKFAKERGPKTISVACCQDKEVLMAVEMARKEKIANAILVGDIEKTKEIAKSIDMDIENYELIDIKDLAEASLKSVELVSQGKADMVMKGLVDTSIILKAVLNKEVGLRTGNVLSHVAVFDVEGYDRLFFVTDAAMNLAPDTNTKKQIIENACTVAHSLDISEPKVAAICAKEKVNPKMKDTVEAKELEEMYERGEIKGCMVGGPFAIDNAVSLEAAKHKGINHPVAGRADILLAPDIEGGNILYKALVFFSKSKNAGVIVGAKAPIILTSRADSEETKLNSIALGVLMAAKA
>NZ_CP045224.1|WP_003420702.1|3919494_3920574_-|butyrate-kinase
MSKIFKILTINPGSTSTKIAVFDNEDLVFEKTLRHSSEEIGKYEKVSDQFEFRKQVIEEALKEGGVKTSELDAVVGRGGLLKPIKGGTYSVSAAMIEDLKVGVLGEHASNLGGIIAKQIGEEVNVPSYIVDPVVVDELEDVARISGMPEISRASVVHALNQKAIARRYAREINKKYEDINLIVAHMGGGVSVGAHKNGKIVDVANALDGEGPFSPERSGGLPVGALVKMCFSGKYTQDEIKKKIKGNGGLVAYLNTNDAREVEERIEAGDEKAKLVYEAMAYQISKEIGASAAVLKGDVKAILLTGGIAYSKMFTEMIADRVKFIADVKVYPGEDEMIALAQGGLRVLTGEEEAQVYDN
>NZ_CP045224.1|WP_003420704.1|3918827_3919505_-|hypothetical-protein
MITNDKRIRIITGHYGSGKSEFAMNYVVKLRDMVSGKVAIADLDVVNVYFRTREKKELMKSLGIQPIDSSINAPTLDLPAVSAEVMSPMVDHSYNSVIDLGGDNVGARVIGRFSHLLKEGDYDMLFVINANREKTQTSEEVIQYIKEIEKSSKLKVTGLINNTHLIRFTTIDDVLRGQKVAKEVSEKCNIPIRYVACLENLVEQLPKDLEGEIFPIKLYMREDWM
>NZ_CP045224.1|WP_003420706.1|3918569_3918785_-|4Fe-4S-binding-protein
MAKGKVSFNQERCKGCGLCVEACPVKIIQLDSNVINKKGYNPATVFEMEKCIGCASCATMCPDVVITVERD
>NZ_CP045224.1|WP_003420707.1|3917461_3918541_-|3-methyl-2-oxobutanoate-dehydrogenase-subunit-VorB
MAKILMKGNEAFGKAAIEAGCKYFFGYPITPQSELPEYLSRELPKIGGAFVQAESEVSAINMVYGGAGAGARVMTSSSSPGVALKQEGITYAVGAEVPCVVLNVMRGGPGLGSIQPSQADYFMSTRGGGNGDYRTPVFAPATVQEAVDMIMEAFDVADYYRSPVMVVADGMIGQMMEPVEFRAPEKKRELPPKDWATVGTKGKRKPNVINSLYLEPEVLEDHCWHLQEKFDAMEKNEVQYEMYKTEDAEFVFAAYGTTSRVVKSAIDILREEGIKAGLIRPKVLWPFPFEAFNQIPNARNILTVEMSMGQMVEDVKMAVEGRLPVYFHGRPGGMTPTPAEIVEKAKKIIAGELVAGGAR
>NZ_CP045224.1|WP_003420710.1|3916709_3917462_-|MFS-transporter
MAVVFKKTEGLQDTQTHYCPGCTHGIIHRLVGEVLEELGVLGDAVGVVPVGCSVLGYKYFNCDTQEAAHGRAPAAATGIKRVHPENTVFTYQGDGDLASIGTAEIVHAAARGEKITTIFVNNTTYGMTGGQMAPTTLVGQRATTAQSGRNAETQGYPIRVSEMLATLTGAVFVERVAVDTPAHVRQAKKAIKKAFQVQQAGLGFGIVEVLSTCPTNWGLAPNDALQWLRDNMIPYYPLGNFKNVEVEEVK
>NZ_CP045224.1|WP_003420711.1|3916151_3916709_-|2-oxoacid:acceptor-oxidoreductase-family-protein
MSTARVICAGFGGQGVMSMGQLLTYAGMLEGKEVSWLPSYGPEMRGGTANCAVTVSNEPVGSPLITDDATAAILLNIPAFEKFKDDVIPGGKIIVNSSLIKEKVDRTDVDVYYIPANELAAELGNDKVANMIMLGAYLKVSDTVDIESVLEAFKKVFGPRKEKFVPLNREALQKGMDATCSKATN
>NZ_CP045224.1|WP_009904773.1|3914633_3915980_-|phosphoglucosamine-mutase
MRKYFGTDGVRGVANTELTCDLAYKLGRAGGFVLAQGDHRVKVVVGKDTRISGDMLEASLIAGLMSVGCDVITVGIIPTPAVAYLTRKYGADCGVVISASHNPVEYNGIKFFNKNGYKLDDEIELKIEEYIDDIDKIDCMPIGENVGRKLHEHCAQRDYVDYLKSIISTDFKGLKVVLDCANGASYKVAPIVFDELGASVISINSSPDGNNINYKCGSTHPEQLQSAVLEHNADLGLAYDGDADRLIAVNEKGQIVDGDHIMILSALNLKKNNKLAQDTLVVTVMSNIGLTIAAKENGINLSTTAVGDRYVLEDMVKNGYNLGGEQSGHMIFLDYNTTGDGVLSSLILANIILQEKKPLSELASIMSQYPQVLVNATIKNENKNKYMEYPEIKTEIERIESILDGNGRVLIRPSGTEPLVRVMLEGKEEGQIKELATNLANLIQEKLS
>NZ_CP045224.1|WP_003421605.1|3936726_3937266_-|anaerobic-ribonucleoside-triphosphate-reductase-activating-protein
MKIRMSSTISYDSIVDGPGLRMVIWTQGCIHNCKECHNPQTHDLCGGFYMDTEEIINKVKSLKLQKGITLSGGEPFLQPEPLEVIAREAKTNGLDVWSYTGFTFEQLLDKRNSAYFKNLNLLKQIDILVDGKFVAEKKDISLKFRGSSNQRIIDVQKSLKYKKVFLVEQYMKDDLSIAE
>NZ_CP045224.1|WP_003421607.1|3937287_3939639_-|anaerobic-ribonucleoside-triphosphate-reductase
MVEFVKKRDGRVIPFNEDRITRAIFLAATNVAEREGIVPDYKLSEQLTQEVIKFLNHKYSESVPSVEDIQDSVVKVLIETGHAKTSEEYIIYRTERSRIRNSKTRLMKAIEEITFEDAEDADIKRENANINGNTAMGTMLQYGSTVSKEFCKTHILKPEHSFAHDNGDIHIHDMDFLNMGTLTCCQIDVKKLFNGGFSTGHGFLREPQDIISYGALAAIAIQSNQNDQHGGQSIPFFDYGLAEGVYKTFKKFYIGNLAKALKLFKGIENNDVIKNIVYNTEKETNQKVGLKRDELYLNLEKEKLIQTFDIDEELVNKMQNFAFEESYKETDKKTYQSMEAFIHNLNTMHSRAGAQVPFSSVNFGTDTSEEGRMVTKNLLLSQERGLGNGETPIFPILIFKVKEGINLNPEDPNYDLFKLSCRVSAKRLFPNFSFLDAPFNAKYYKKGEPDTEATYMGCRTRVLSNVCGSETVSGRGNISFTTVNLPRLGIKHGIINNEKANLDGFFEELDEKINLIIEQLLERLEVQGNKKMKNFPFLMGQGVWKGSDELGPEDTLKEVIKQGTLTIGFIGLAECLIALIGKHHGESKEAQELGLKIVSHMRDKMDEATDKYKLNFSLMGTPAEGLSGRFTKIDKKVYGEIKGITDKEYYTNSFHVPVYYNISAYDKIEIEAPYHELTNAGHITYVELDGDPSDNLEAFETVIKAMKDLGIGYGSINHPVDRDPICGFSGVITSNICPVCGRNEDESDIKFERIRRITGYLVGTVDRFNNAKKAEVRDRVKHR
>NZ_CP045224.1|WP_003421608.1|3940011_3941196_+|pyridoxal-phosphate-dependent-aminotransferase
MLSKRLNFITPSYTIGISSKVKEMENNGIKVINLSIGEPDFNVPNNAKSYGIDSLNKDYTKYDLVPGLKILREEICKKLIEENNCKYSIDEIVVSSGAKNSITNTLLALTDEGDEVLLPKPYWVSYPEMVKLVNAVPIFIDTKKENDFKLTKEELEKSITDKTKILVINNPSNPTGSVYTKDELIEIVDVCIQNKIYILADEIYEKICYSGEFTSIASLSEEAKDITITINGFSKSAAMTGLRLGYTASNKAIAKAMSSIQGHLISHPSLTAQYIAYGALKDCSTDIDNMVKTYKSRRDLIKSKLDSIENIGYVNPNGAFYAFIDLSKVSEKFEYKDSFSIEFCNQFLEEYNVAVVPGIAFGMDKYIRISYACSENTFLSGLNKLKEFVYKIMA
>NZ_CP045224.1|WP_009904772.1|3953678_3954383_-|N-acetylmuramoyl-L-alanine-amidase-CwlD
MRKYIKHIIFSFAMICLVVVSIFEIKNISEDVIKYMPVTNKTIILDAGHGGIDPGALNKDKSTSEKDINLAITLKLRELIESSGGLVILTREDDSSLYKEENNKTTRQKYNENLKNRKEIISNSNANMFVSIHLNAFEQSKYYGAQTFYPKDKQDSKELSKCIQEELKRVVDKTNNREVKPRDDIYLLKENNIPSVLIECGFLSNEKESKLLTDETYQEKIAWAIYIGIQKYLS
>NZ_CP045224.1|WP_003421105.1|3954891_3955284_-|30S-ribosomal-protein-S9
MANVQYYGTGRRKSSVARVRLVAGEGNILVNGRALENYFNYETLIRDVKQPLVLTGNENKYDVIVKVEGGGFTGQAGAIRHGISRALLKADLDLRPALKKEGFLTRDARMKERKKYGLKAARRAPQFSKR
>NZ_CP045224.1|WP_003421107.1|3955312_3955744_-|50S-ribosomal-protein-L13
MKSYIAKPADVQRKWYLVDAEGKTLGRLATEIATVLRGKHKPTFTPHVDGGDFVVVVNAEKIVLSGKKLDQKYYRYHTGYVGGLKEISYRDMMDKKPEEVISHAVSGMLPKNKLRSRMMTRLRVFAGAEHTHAAQNPEVLNFK
>NZ_CP045224.1|WP_003421109.1|3955863_3956595_-|tRNA-pseudouridine(38-40)-synthase-TruA
MRNIKITIQYNGKNYCGWQKQLDSLGIQGTIERAIYDITKEKVSLIGSGRTDSGVHAIGQIANFKTNSSISIESIPMALNAKLPKDISVIDACEVNDDFHSRYSAKGKTYKYLVYNSKFRNPILSEISYQVKYELDFDKMCSEAKLLLGTHDFKGFMSSGSSVKDTVRTIYDIDIIRKDDLITFEISGNGFLYNMVRIIVGTLVDIGRGRINEPFLDIIQSKTRSRCGHTAPAQGLFLKKVHY
>NZ_CP045224.1|WP_003421111.1|3956627_3957431_-|energy-coupling-factor-transporter-transmembrane-protein-EcfT
MLKDITIGQYYPTSSAIHKLDPRIKLVATIVFMISIFVVNKFWPYIVVLLCLLAMIKLANIPIKYIVKGVKPLKWIILFTFFINIFFLPGDEIWSFGFLTITSQGLRQAIFMAIRLIFLVVGTSLLTLTTSPIELTDGIERLLNPFKKIGLPVHELAMMMTIALRFIPTLLDETDKIMKAQMSRGADFESKNLINRAKNLVPLLVPLFVSAFRRADELAMAMEARCYRGGHNRTKMRESVISRRDYMACVFQVVYLGAIIATRFIAI
>NZ_CP045224.1|WP_003421113.1|3957424_3958291_-|energy-coupling-factor-transporter-ATPase
MSIIVKNLTHIYNEGMPFASKALDDISFEIKDRDFVGLIGHTGSGKSTLIQHLNGLLKPSSGEIFINDFNITDKNLNLTEIRKRVGVVFQYPEYQLFEETIDKDIAFGPSNLGLEESEIHNRVKASMEAVGLDYEEFKDKSPFELSGGQKRRVAIAGVIAMNPEVLILDEPTAGLDPGGRDEIFNLIKSLHEKKNMTIILSSHSMDDMAKLAKTLIVMNHGSVEFIGTPREVFKSNASKLKDIGLDIPQVLELALKLREKGFDISEDILTLEEAKQEILKVVRGRGLC
>NZ_CP045224.1|WP_003421115.1|3958278_3959112_-|energy-coupling-factor-transporter-ATPase
MDNIVKVNNISFEYITDEAKLKAIDNLSLDVKKGEFVAIIGHNGSGKSTLSKNLNAILMPTEGNILIDGMNTKEEERLWDIRQTAGMVFQNPDNQIVATIVEEDVAFGPENLGIEPKEIRRIVEESLKSVGMYDLRDRQPHLLSGGQKQRVAIAGIIAMRPKCIIFDEATAMLDPSGRKEVMKTIKRLNKEENITVIHITHFMEEAVEADRVVVMEKGKKILEGTPREVFSKIKMLKEIGLDVPCMTELSSLLIEEGINISGDILTVDEMVMELCRL

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Crispr_ID: NZ_CP045224_15

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045224_15

4054075-4054160

Orphan

Consensus_repeat	Method
AAAGTGCTAACGCACAGCGCCAAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045224_15

>merge|NZ_CP045224|15|4054075-4054160|CRISPRCasFinder
AAAGTGCTAACGCACAGCGCCAACAAACAAACTTCAGATGCGTTCAGTTTATTCTGTTGCTTAAAGTGCTAATGCACAGCGCCAAC

>NZ_CP045224|15|13|4054075-4054160|CRISPRCasFinder
AAAGTGCTAACGCACAGCGCCAAC	AAACAAACTTCAGATGCGTTCAGTTTATTCTGTTGCTT
AAAGTGCTAATGCACAGCGCCAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045224.1\|WP_009887752.1\|4072594_4072945_-\|YbaB/EbfC-family-nucleoid-associated-protein	unknown	unknown	gnl\|CDD\|234669
NZ_CP045224.1\|WP_003421260.1\|4042691_4046123_-\|pyruvate-carboxylase	unknown	unknown	gnl\|CDD\|237263
NZ_CP045224.1\|WP_003421612.1\|4056246_4057452_+\|glycosyl-transferase	unknown	unknown	gnl\|CDD\|340861
NZ_CP045224.1\|WP_003421255.1\|4039099_4039594_-\|UvrB/UvrC-motif-containing-protein	unknown	unknown	gnl\|CDD\|226397
NZ_CP045224.1\|WP_009887752.1\|4058496_4058847_-\|YbaB/EbfC-family-nucleoid-associated-protein	unknown	unknown	gnl\|CDD\|234669
NZ_CP045224.1\|WP_003421256.1\|4039600_4040065_-\|CtsR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|226869
NZ_CP045224.1\|WP_003421251.1\|4038058_4039084_-\|protein-arginine-kinase	unknown	unknown	gnl\|CDD\|234894
NZ_CP045224.1\|WP_009904742.1\|4040521_4042450_-\|elongation-factor-G	unknown	unknown	gnl\|CDD\|237186
NZ_CP045224.1\|WP_003421262.1\|4046435_4046849_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_003421629.1\|4063519_4064401_-\|mechanosensitive-ion-channel	unknown	unknown	gnl\|CDD\|182386
NZ_CP045224.1\|WP_003421618.1\|4057884_4058484_-\|recombination-protein-RecR	unknown	unknown	gnl\|CDD\|234616
NZ_CP045224.1\|WP_003421627.1\|4061789_4063061_-\|serine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235461
NZ_CP045224.1\|WP_003421624.1\|4061012_4061468_-\|nucleoside-deaminase	unknown	unknown	gnl\|CDD\|223663
NZ_CP045224.1\|WP_003421247.1\|4034071_4035445_-\|DNA-repair-protein-RadA	unknown	unknown	gnl\|CDD\|236994
NZ_CP045224.1\|WP_003421631.1\|4064412_4064922_-\|transcription-repressor-NadR	unknown	unknown	gnl\|CDD\|224740
NZ_CP045224.1\|WP_131005793.1\|4057522_4057684_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_003421245.1\|4032998_4034069_-\|DNA-integrity-scanning-protein-DisA	unknown	unknown	gnl\|CDD\|237395
NZ_CP045224.1\|WP_003421243.1\|4031815_4032910_-\|PIN/TRAM-domain-containing-protein	unknown	unknown	gnl\|CDD\|227292
NZ_CP045224.1\|WP_131005793.1\|4071621_4071783_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045224.1\|WP_003421249.1\|4035624_4038072_-\|ATP-dependent-Clp-protease-ATP-binding-subunit	unknown	unknown	gnl\|CDD\|223616

Protein	Function_ID	Function_description	E-value
NZ_CP045224.1\|WP_009887752.1\|4072594_4072945_-\|YbaB/EbfC-family-nucleoid-associated-protein	gnl\|CDD\|234669	PRK00153, PRK00153, YbaB/EbfC family nucleoid-associated protein.	1.04649e-45
NZ_CP045224.1\|WP_003421260.1\|4042691_4046123_-\|pyruvate-carboxylase	gnl\|CDD\|237263	PRK12999, PRK12999, pyruvate carboxylase; Reviewed.	0
NZ_CP045224.1\|WP_003421612.1\|4056246_4057452_+\|glycosyl-transferase	gnl\|CDD\|340861	cd17507, GT28_Beta-DGS-like, beta-diglucosyldiacylglycerol synthase and similar proteins. beta-diglucosyldiacylglycerol synthase (processive diacylglycerol beta-glucosyltransferase EC 2.4.1.315) is involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. This family of glycosyltransferases also contains plant major galactolipid synthase (chloroplastic monogalactosyldiacylglycerol synthase 1 EC 2.4.1.46). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.	1.3214e-147
NZ_CP045224.1\|WP_003421255.1\|4039099_4039594_-\|UvrB/UvrC-motif-containing-protein	gnl\|CDD\|226397	COG3880, COG3880, Modulator of heat shock repressor CtsR, McsA [Signal transduction mechanisms].	2.05547e-43
NZ_CP045224.1\|WP_009887752.1\|4058496_4058847_-\|YbaB/EbfC-family-nucleoid-associated-protein	gnl\|CDD\|234669	PRK00153, PRK00153, YbaB/EbfC family nucleoid-associated protein.	1.04649e-45
NZ_CP045224.1\|WP_003421256.1\|4039600_4040065_-\|CtsR-family-transcriptional-regulator	gnl\|CDD\|226869	COG4463, CtsR, Transcriptional repressor of class III stress genes [Transcription].	1.67585e-42
NZ_CP045224.1\|WP_003421251.1\|4038058_4039084_-\|protein-arginine-kinase	gnl\|CDD\|234894	PRK01059, PRK01059, ATP:guanido phosphotransferase; Provisional.	3.36621e-164
NZ_CP045224.1\|WP_009904742.1\|4040521_4042450_-\|elongation-factor-G	gnl\|CDD\|237186	PRK12740, PRK12740, elongation factor G-like protein EF-G2.	0
NZ_CP045224.1\|WP_003421624.1\|4061012_4061468_-\|nucleoside-deaminase	gnl\|CDD\|223663	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis].	7.52683e-52
NZ_CP045224.1\|WP_003421629.1\|4063519_4064401_-\|mechanosensitive-ion-channel	gnl\|CDD\|182386	PRK10334, PRK10334, small-conductance mechanosensitive channel MscS.	1.89288e-61
NZ_CP045224.1\|WP_003421627.1\|4061789_4063061_-\|serine--tRNA-ligase	gnl\|CDD\|235461	PRK05431, PRK05431, seryl-tRNA synthetase; Provisional.	0
NZ_CP045224.1\|WP_003421249.1\|4035624_4038072_-\|ATP-dependent-Clp-protease-ATP-binding-subunit	gnl\|CDD\|223616	COG0542, clpA, ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones].	0
NZ_CP045224.1\|WP_003421631.1\|4064412_4064922_-\|transcription-repressor-NadR	gnl\|CDD\|224740	COG1827, COG1827, Predicted small molecule binding protein (contains 3H domain) [General function prediction only].	1.01095e-43
NZ_CP045224.1\|WP_003421618.1\|4057884_4058484_-\|recombination-protein-RecR	gnl\|CDD\|234616	PRK00076, recR, recombination protein RecR; Reviewed.	6.04881e-129
NZ_CP045224.1\|WP_003421245.1\|4032998_4034069_-\|DNA-integrity-scanning-protein-DisA	gnl\|CDD\|237395	PRK13482, PRK13482, DNA integrity scanning protein DisA; Provisional.	0
NZ_CP045224.1\|WP_003421243.1\|4031815_4032910_-\|PIN/TRAM-domain-containing-protein	gnl\|CDD\|227292	COG4956, COG4956, Integral membrane protein (PIN domain superfamily) [General function prediction only].	9.37001e-140
NZ_CP045224.1\|WP_003421247.1\|4034071_4035445_-\|DNA-repair-protein-RadA	gnl\|CDD\|236994	PRK11823, PRK11823, DNA repair protein RadA; Provisional.	0

>NZ_CP045224.1|WP_003421262.1|4046435_4046849_-|hypothetical-protein
MYIVIGNEIVDSEELKVIIDKNSKFKVEKDLSKSTKREDVIAYQLSIDLNYLDSLISEQCNLASLSDEEKFDEYMTLSDELALNLEELMPKYTIINARAYKLDEVDGVVKIILAVAYADLGHLKLSDVLMRISRQVD
>NZ_CP045224.1|WP_003421260.1|4042691_4046123_-|pyruvate-carboxylase
MLKKFNKILVANRGEIAIRIFRACSELGIKSVGIYSKEDKYGLFRTKADESYLIGEGKGPIDAYLDMDGIIDLAKRKKVDAIHPGYGFLAENAEFARKCEENGITFIGPSSKVMNMMGDKINSKKIAKEVNVQTIPGVEKAIRSTEEAKEVANKIGYPVMIKASNGGGGRGMRIVHHEEDLELEYETACSESRKAFGEDIIFIEKYIADPKHIEVQILGDNYGNIVHLYERDCSVQRRHQKIIEYAPAFSLDDKVRKEICEDAVKLSKHVGYSNAGTLEFLVDANGGHYFIEMNTRVQVEHTVTEMVTGIDIVQSQILIAQGYSLDSEEINIKSQDDVEIRGYSIQCRITTEDPKNKFMPDTGKIQVYRTGSGFGIRLDGGNGFTGANISPHYDSLLVKTISWDRTFQGAINKTIRSIKELRVRGVKTNVGFLVNVLNNPIFSNGKCSTKFIDENPDLFEITESKDRGTKLLQFIGDVIVNDNACKEKPLFDALHDPRMDKDGSKAEGSKILFDKLGKSAYIEKIKNDKKLLLTDTTMRDAHQSLLATRIRTYDLLKAAKPTEKYQKDLFSLEMWGGATYDVAYRFLKESPWRRLQKLREEIPSIMFQMLLRASNGVGYKNYPDNVIEEFTKESARQGIDVFRIFDSLNWVENMKPSINTALETGKIVEATMCYTGDILDKTKTKYNLEYYIKMAQELESLGADIIAIKDMSGLLKPYSAYTLVKELKKNIKAPIHLHTHDTSGNGVATCLMASEAGVDIIDAALESMAGLTSQPSLNAIVEALKNTERDTGIDLFGYDELGKYYKDLRKVYSKFESDLTNSCAEIYNFEIPGGQYTNLKPQADSLGLVNRFDEVKEKYKEANEVVGDIIKVTPSSKVVGDLAIFMTKNKLDKDNIIEEGKNLSFPDSVVDYCKGMIGQPEGGIPKDLQEVVLKGEEAITVRPGSLLPEEDFDEIAKYLNEKYDINANIRNVISYALYPKVYEDYIKHLQHYNDISKLESDVFFYGLNKNEECEVEIEEGKVLTIRLVEIGEVKENGFRTIGFELNGMVREVEIKDKNFSGKINNVEKADMNDPLQIGASIPGKVIKIMVKEEDEVKANQPLIVIEAMKMETIIVAKTDGVIKSIKVKEDDMVEDKQLLMIMK
>NZ_CP045224.1|WP_009904742.1|4040521_4042450_-|elongation-factor-G
MKVYDSKMLRNVAVLGHSGCGKTNLIETIAYTANTNKIPKLTDKVNMTYSMGLIPIEYNDYKFNLLDTPGYFDFSGDVVSSLRASDAAIIVIDATAPIQVGTEKSLELTESIPKIMFINKIDNEKARYKDAIAMLREKYNNKIVPMISPIYKDKNFVKLHNVFENIDDLEGEFKEQAMSVKEALMELIAETDDQILDKYFNGEELTTEEIQKGIIIGIQRGDIIPVICGSTINNIGTKEILDTISNYLEPIFTEESKPFRGLVFKTMVDPFVGKMSYIKITEGVLSKDKDVFNINKNVKEKIANIYTLKNSELVEVEKAKAGDIVVVTKINSLKTGDTISIDKDAEALENIDFPKPQIYYAVTPKNKGDEEKVASVLNRLVEEDPTLHSYRNTETKQALLGGQGELHIKTIKNKMKDKFGVDVELNDLKVPYRETIKGKSDVQGKHKKQSGGHGQYGDVKIRFERCESDFEFAEEIFGGSVPKQYIPAVEKGIKDSMQKGILAGYPVTNIKATLYDGSYHDVDSSEMAFKMAASVAFKKGMEEAHPILLEPIMKLKITVPEEYMGDVMGDINKRRGKIFGMEPDDKGKQIIFAEAPQAETFKYAIDLRAMTQGRGYFEMELERYGEVPSQFAEKIIGLATAK
>NZ_CP045224.1|WP_003421256.1|4039600_4040065_-|CtsR-family-transcriptional-regulator
MATMTDIIEKFIKDLMEEDNSIQIQRNELANLFSCAPSQINYVLTTRFTIDRGYYIESKKGGGGYVQIEKIRKSKDGHIRELLNEKIGNQISYKKAKELLEGLKESDLINERELKLILYAIDDKSLCMPIYELKEKVRSNILKNIIIGLFSIEE
>NZ_CP045224.1|WP_003421255.1|4039099_4039594_-|UvrB/UvrC-motif-containing-protein
MLCQKCNKNKASVYYNKIVNGEKTEMYLCSECAKENTEMNFNLDMPFSMMDIFSNLGFQPKKELEEKLVCPKCNTTYSEFKNNGRFGCSECYNAFSSQVNPMLQNIHGHIEHTGKAPKKSFYKISVENEIKELKEDLDRAIKNEEYELAAQFRDKIKYLKGSID
>NZ_CP045224.1|WP_003421251.1|4038058_4039084_-|protein-arginine-kinase
MKENIVMKSRVRLARNLNNYSFPNKLDKECAMEIIEKVKNAFINSNLEQKEEFDFYKIEDLDQSKKMLMVEEHIISPDLAESDKSAVIVKKDKTVSIMINEEDHIRIQTMCDDLNLEYAYSVANEIDDLLESSLEYAFSTKLGYLTSCPTNTGTGMRASVMMHLPALSQLGYMDELYKISSQIGIAIRGIYGERTEALGNIYQISNQLTLGRTESNIIENVSGLTKDAISKEIKAREILQKKLGIKLEDKIFRSIGTLENSRIMSSAEAMSHLSNIKMGIEMNYIDKLDLRAIEQLMIGIQPAHQSIMYKSDDVENRDINRATYIRETLEKLRGGMNCELQ
>NZ_CP045224.1|WP_003421249.1|4035624_4038072_-|ATP-dependent-Clp-protease-ATP-binding-subunit
MNFNRFTQRAKKAIDLAFESAKGLGHNIVGSEHILLGLLREEEGIAAKVLSKVGFTEAYLEGKIVDMEGKGEEISEDIVLSPRSKQILELSGMFANKLKTNYIGTEHILLAIIQEGEGIANKILNYAGVNDRTLAQLTIDMMGISDKNQYKAENSYTGNQNQAESKVLDKYGRNLTLYAKQNKIDPVIGREKEIQRVIQILSRRTKNNPVLIGDPGVGKTAIAEGLATNIALGNVPETLKNKTLYSLEMGSLLAGAKYRGEFEERIKEVVDEVVKNGNIILFIDEMHTIIGAGSTGEGSIDASNILKPALARGEIQVIGATTIDEYRKHVEKDSALERRFQPVMVDEPTKEDSIKILEGLRDKYEAHHKVKITDDAIKAAVELSTRYISDRYLPDKAIDLIDEAASKVRLKENTPPSEIKKLELEIENIDKEKEEAVRCQDFEKAAKIRDEQGLLKKQLEDVRERWSKSSKHSDLVDGEVIAEVVGLWTGIPVNKILEEEADRLLRLEEILHNRVIGQEQAVKSISKAIRRSRAGLKDPNRPIGSFLFLGPTGVGKTELSKALAEVQFGDENQIIRIDMSEYMEKHAVSRMIGSPPGYVGHDEGGQLTEKVRRNPYSVILFDEIEKAHPDVFNILLQILDDGRLTDSKGRTVDFKNTIVIMTSNVGASTIGRQKTLGFSIAKGDEEEKSQYEKMKENIMGELKQRFRPEFLNRIDDIIVFHSLNENHISKIVLLMAAKLQERLKEMDIKLEMSDEAVKLISKSGFDLEYGARPLKRALQKELEDELSEAILKGNVKKGSNVVAKVKDEKIVFETK
>NZ_CP045224.1|WP_003421247.1|4034071_4035445_-|DNA-repair-protein-RadA
MAKIKTKYVCQSCGYETAKWLGKCPECTKWNTFVEEIDQKSTKKEVFIIDKSSSKPVTINSIESKEEERFTTDINELDRVLGGGIVKGSLVLVGGDPGIGKSTLLIQVSSNVANLGKTVLYITGEESESQIKMRAKRLGINSENLYIFAENNLSIIESYLEVVNPELIILDSIQTVFSPEISSAPGTVSQIKEGTSKFMKISKKMGISTFIVGHVTKEGSLAGPKLLEHMVDTVLYFEGERYNTYRLVRAVKNRFGSTNELGVFEMRDLGLVELDNPSKILISEKPKDVAGSVIISTVEGTRPMLLELQALVSPTSFGIPKRTSTGVDYNRVGMLLAVLEKRVGLQIQNQDVYINIVGGIKINEPSIDLGIAISVASSFRNIPIDEDIAVTGEVGLTGEVRAVSFIEKRIAECKKLGFKKIVVPRSNYDVIKDTKGIEIWPVDNLRQAINIVLGRNQ
>NZ_CP045224.1|WP_003421245.1|4032998_4034069_-|DNA-integrity-scanning-protein-DisA
MENFLDNKNMLYALKMISPGTPLRLGLNNVLRAKTGGLIVIATNEDVMKIVDGGFAINAEYSPSYLYELAKMDGAIVLSGDVKKILFANAQLIPDYFIETSETGTRHRTAERVAKQTGAIVIGISQRRNVITVYRGNEKYVVEDISKIFTKANQAIQTLEKYKTVLDQAITNLNALEFNDLVTIYDVALVMQKMEMVMRVTSIIEKYVIELGDEGTLVSMQLEELMGTTRIDQKLIFKDYNKENTEIKELMKKVKNLNSEELIELVNMAKLLGYSGFSESMDMPIKTRGYRILSKIHRLPTAIIENLVNYFENFQQILDASIEELDEVEGIGEIRATYIKNGLIKMKQLVLLDRHI
>NZ_CP045224.1|WP_003421243.1|4031815_4032910_-|PIN/TRAM-domain-containing-protein
MIRKVTRILFILLGFTIGITTYLTLMKDFEILTFGKETYGYIAAVVAGIIIAILGYFIEPWVVNKVKEIAKIVDKELSKYPQTDILLGSMGLIVGFVIAYLLSGLVNRIPIVGGILSLLLYLFLGYLGMKVALKSKNDLFNIGKLGRLANPIKDKDKDKENKKDIKAIPPKVLDTSVIIDGRIADICKTGFIEGKLIIPAFVLEELRHIADSSDDLKRVRGRRGLDILNIIQKELNIEVEISERDFDDIAEVDSKLLKLAQVLNGKVVTNDYNLNKVAQFQGVEVLNINELANAIKPVAIPGEDMVVQVVKEGKEAQQGVAYLDDGTMIVVDGGRKYMNETIKVLVTSVLQTPAGRMIFAKPKN
>NZ_CP045224.1|WP_003421612.1|4056246_4057452_+|glycosyl-transferase
MSKKVLIMSASTGGGHNRAALAIKEELTSKTLDGEPIECEIIDSLKLVNNTMDKIISRGYEKSAIYTPKAYGSVYRLSETNLLSKNEFKDNLLITFMAKKFKKLIRSEKPDLIIGTHPFPMIALSTLKKNFNLHNNESNAYTDHFYKHYTNTINVPPLISVLTDYTTHSTWIQNEIDYYIVGHEYVKELLVFDGVEPSKIRTFGIPVEKSFLSHRDKDTVLSELNLSPDKLTVLLMGGSFGAGNIKETLDELLDTDRDFQILVITGKNESLKEKIEKKLISRYHDKNVCVLGYTDKMNDILASIDVLVSKPGGLTTTEALLKDVPMIVPYYIPGQEEENLDFLSNCGAALRTTKKYNLSILLKVLIDDPSRLEMLKRNIKSIRKSNSAQNIANLILNIISG
>NZ_CP045224.1|WP_131005793.1|4057522_4057684_-|hypothetical-protein
MKSKDKPKYDDFEDISFSNKKKTKKNVRNKNAEFRNNYKNYQYDYEEDFYEPI
>NZ_CP045224.1|WP_003421618.1|4057884_4058484_-|recombination-protein-RecR
MQVYTGPITRLIEEFSKLPGVGRKTAQRLAFHIINMNTNDVEALSKAIIDAKREIRYCSICCNITDTDPCSMCSNKSRDSSVICVVEDPRDVAAMERTREFKGQYHVLNGVISPMDGIGPDMLKIKELIQRLGNQEVKEIIMATNPTIEGEATAMYIARLVKPMGIKVTRIAHGLPVGGDLEYADEVTISKALEGRREI
>NZ_CP045224.1|WP_009887752.1|4058496_4058847_-|YbaB/EbfC-family-nucleoid-associated-protein
MAKKGFGGGMMPGGGNMNNLLKQAQKMQENMQKAQQELESKEVEASVGGGAVTVKVNGKKEVIDITIKPEVVDPDDIEMLQDLVLSAVNQALRNIDDIQASQMSKVTGGMNIPGLF
>NZ_CP045224.1|WP_003421624.1|4061012_4061468_-|nucleoside-deaminase
MESSFYMKEALKEAYKAYNKKETPIGAIIVKDNQIIARAHNLTETLKDSTAHAEILAIKQASEKLGGWRLTDCDLYVTMEPCIMCSGAIVNSRIKKLIIGTRHVKNSYIEKQHEFKLDYFNNNNVKVAFDVLQEECSIILQEFFKALRKRD
>NZ_CP045224.1|WP_003421627.1|4061789_4063061_-|serine--tRNA-ligase
MLDIKRIRENLDDIKKAMERRGEKEFDLDAVVELDNKRREILQEVEVMKNELNVNSKNIPQLIKEGKDVTEEKARLKELSDKIKGIDEKVKEVEAKMEYALMRIPNVPHPEVPQGETDEDNVQIRTWGEPTKFDFEHKAHWDIGTGLGILDFERAGKITGSRFTLYRGLGARLERSLMNFFLNTHTAKHGYTEVLPPFMANRNSFIGTGQLPKFEEDMFKIEGLEYFLIPTAEVPVTNIHANEILDVAELPIKYCAYTPCFRSEAGSAGRDTRGLVRQHQFNKVELVKFVKPEDSYNELESLTHDAETMLQMLGLPYRVVKICTGDLGFTAAFKYDLEVWMPSYNRYVEISSCSNFEDFQARRAGIRFKRDKKSKAEYVHTLNGSGLAIGRCLAAILENYQQADGSVVVPEELRPYMGVDVIR
>NZ_CP045224.1|WP_003421629.1|4063519_4064401_-|mechanosensitive-ion-channel
MNFLSLAKSASTNSNITKRTLENMLDNFSDNIPNIIYAIIVFVIGIYISKIVRRMVSKFLIKYGMSKGVNNFIVYGIYISMLSIISLISLGIIGIQTTSVVAVLGAAGFSIGLAFKEILSNLGSGMIILFFKPFNIGDYIQGSGVEGTVSDIQIFSTVLKTPDNKTIIIPNFQLTSNNIINYTHQNKRRIDFSYNISYDSDIDLVKSILNEIFINEKRILDDPRPIIGLNSIGNNTMQIVARPWVKTDDYWDVYFDVMEKVKNKFDENNIKVPFVPSSLLFNNMSNLNTMDKR
>NZ_CP045224.1|WP_003421631.1|4064412_4064922_-|transcription-repressor-NadR
MNSNERRSKLIDILKESKHPVKGGTLAELLNVSRQVIVQDIAIIRARGFEIIATPQGYIIYNQPYFTKQIKCKNHKDSKEIYDELKIIVDLGGIIKDVIVNHPTYGQITAELNIYSKMDIDNFMKKVETNEFKQLSVLTECSHIHTIEAIKEETIEAIVKELKDNGILS
>NZ_CP045224.1|WP_131005793.1|4071621_4071783_-|hypothetical-protein
MKSKDKPKYDDFEDISFSNKKKTKKNVRNKNAEFRNNYKNYQYDYEEDFYEPI
>NZ_CP045224.1|WP_009887752.1|4072594_4072945_-|YbaB/EbfC-family-nucleoid-associated-protein
MAKKGFGGGMMPGGGNMNNLLKQAQKMQENMQKAQQELESKEVEASVGGGAVTVKVNGKKEVIDITIKPEVVDPDDIEMLQDLVLSAVNQALRNIDDIQASQMSKVTGGMNIPGLF

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP045224_12	12.6\|2802673\|38\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2802673-2802710	38	NZ_CP045224.1	4043957-4043994	0	1.0
NZ_CP045224_15	15.1\|4054099\|38\|NZ_CP045224\|CRISPRCasFinder	4054099-4054136	38	NZ_CP045224.1	2999059-2999096	1	0.974
NZ_CP045224_15	15.1\|4054099\|38\|NZ_CP045224\|CRISPRCasFinder	4054099-4054136	38	NZ_CP045224.1	4087925-4087962	1	0.974
NZ_CP045224_15	15.1\|4054099\|38\|NZ_CP045224\|CRISPRCasFinder	4054099-4054136	38	NZ_CP045224.1	143447-143484	1	0.974
NZ_CP045224_15	15.1\|4054099\|38\|NZ_CP045224\|CRISPRCasFinder	4054099-4054136	38	NZ_CP045224.1	273928-273965	1	0.974
NZ_CP045224_15	15.1\|4054099\|38\|NZ_CP045224\|CRISPRCasFinder	4054099-4054136	38	NZ_CP045224.1	1027183-1027220	1	0.974
NZ_CP045224_1	1.4\|337251\|22\|NZ_CP045224\|CRT	337251-337272	22	NZ_CP045224.1	338103-338124	2	0.909
NZ_CP045224_1	1.6\|337347\|25\|NZ_CP045224\|CRT	337347-337371	25	NZ_CP045224.1	337023-337047	2	0.92
NZ_CP045224_2	2.15\|455313\|36\|NZ_CP045224\|CRT	455313-455348	36	NZ_CP045224.1	455448-455483	2	0.944
NZ_CP045224_15	15.1\|4054099\|38\|NZ_CP045224\|CRISPRCasFinder	4054099-4054136	38	NZ_CP045224.1	3928769-3928806	2	0.947
NZ_CP045224_15	15.1\|4054099\|38\|NZ_CP045224\|CRISPRCasFinder	4054099-4054136	38	NZ_CP045224.1	3934183-3934220	2	0.947
NZ_CP045224_15	15.1\|4054099\|38\|NZ_CP045224\|CRISPRCasFinder	4054099-4054136	38	NZ_CP045224.1	3944744-3944781	2	0.947
NZ_CP045224_15	15.1\|4054099\|38\|NZ_CP045224\|CRISPRCasFinder	4054099-4054136	38	NZ_CP045224.1	3951628-3951665	2	0.947
NZ_CP045224_15	15.1\|4054099\|38\|NZ_CP045224\|CRISPRCasFinder	4054099-4054136	38	NZ_CP045224.1	4082427-4082464	2	0.947

1. spacer 12.6|2802673|38|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to position: 4043957-4043994, mismatch: 0, identity: 1.0

gagtgtatgctgaatatggtttaagaagtcctgacata	CRISPR spacer
gagtgtatgctgaatatggtttaagaagtcctgacata	Protospacer
**************************************

2. spacer 15.1|4054099|38|NZ_CP045224|CRISPRCasFinder matches to position: 2999059-2999096, mismatch: 1, identity: 0.974

aaacaaacttcagatgcgttcagtttattctgttgctt	CRISPR spacer
aaacaaacttcacatgcgttcagtttattctgttgctt	Protospacer
************ *************************

3. spacer 15.1|4054099|38|NZ_CP045224|CRISPRCasFinder matches to position: 4087925-4087962, mismatch: 1, identity: 0.974

aaacaaacttcagatgcgttcagtttattctgttgctt	CRISPR spacer
aaacaaacttcacatgcgttcagtttattctgttgctt	Protospacer
************ *************************

4. spacer 15.1|4054099|38|NZ_CP045224|CRISPRCasFinder matches to position: 143447-143484, mismatch: 1, identity: 0.974

aaacaaacttcagatgcgttcagtttattctgttgctt	CRISPR spacer
aaacaaacttcacatgcgttcagtttattctgttgctt	Protospacer
************ *************************

5. spacer 15.1|4054099|38|NZ_CP045224|CRISPRCasFinder matches to position: 273928-273965, mismatch: 1, identity: 0.974

aaacaaacttcagatgcgttcagtttattctgttgctt	CRISPR spacer
aaacaaacttcacatgcgttcagtttattctgttgctt	Protospacer
************ *************************

6. spacer 15.1|4054099|38|NZ_CP045224|CRISPRCasFinder matches to position: 1027183-1027220, mismatch: 1, identity: 0.974

aaacaaacttcagatgcgttcagtttattctgttgctt	CRISPR spacer
aaacaaacttcacatgcgttcagtttattctgttgctt	Protospacer
************ *************************

7. spacer 1.4|337251|22|NZ_CP045224|CRT matches to position: 338103-338124, mismatch: 2, identity: 0.909

ggcagtaggagcaacaggaata	CRISPR spacer
ggcaacaggagcaacaggaata	Protospacer
****..****************

8. spacer 1.6|337347|25|NZ_CP045224|CRT matches to position: 337023-337047, mismatch: 2, identity: 0.92

agcaacagggacaaccggagcagat	CRISPR spacer
agcaacaggtgcaaccggagcagat	Protospacer
********* .**************

9. spacer 2.15|455313|36|NZ_CP045224|CRT matches to position: 455448-455483, mismatch: 2, identity: 0.944

gcagtaggagcaaccggagcaacgggagtagcaggt	CRISPR spacer
gcagtaggagcaaccggagcaaatggagtagcaggt	Protospacer
**********************  ************

10. spacer 15.1|4054099|38|NZ_CP045224|CRISPRCasFinder matches to position: 3928769-3928806, mismatch: 2, identity: 0.947

aaacaaacttcagatgcgttcagtttattctgttgctt	CRISPR spacer
aaacaaacttcacatgtgttcagtttattctgttgctt	Protospacer
************ ***.*********************

11. spacer 15.1|4054099|38|NZ_CP045224|CRISPRCasFinder matches to position: 3934183-3934220, mismatch: 2, identity: 0.947

aaacaaacttcagatgcgttcagtttattctgttgctt	CRISPR spacer
aaacaaacttcacatgtgttcagtttattctgttgctt	Protospacer
************ ***.*********************

12. spacer 15.1|4054099|38|NZ_CP045224|CRISPRCasFinder matches to position: 3944744-3944781, mismatch: 2, identity: 0.947

aaacaaacttcagatgcgttcagtttattctgttgctt	CRISPR spacer
aaacaaacttcacatgtgttcagtttattctgttgctt	Protospacer
************ ***.*********************

13. spacer 15.1|4054099|38|NZ_CP045224|CRISPRCasFinder matches to position: 3951628-3951665, mismatch: 2, identity: 0.947

aaacaaacttcagatgcgttcagtttattctgttgctt	CRISPR spacer
aaacaaacttcacatgtgttcagtttattctgttgctt	Protospacer
************ ***.*********************

14. spacer 15.1|4054099|38|NZ_CP045224|CRISPRCasFinder matches to position: 4082427-4082464, mismatch: 2, identity: 0.947

aaacaaacttcagatgcgttcagtttattctgttgctt	CRISPR spacer
aaacaaacttcacatgtgttcagtttattctgttgctt	Protospacer
************ ***.*********************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP045224_3	3.6\|779309\|34\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779309-779342	34	NZ_CP029155	Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence	96290-96323	0	1.0
NZ_CP045224_3	3.6\|779309\|34\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779309-779342	34	MF547662	Clostridioides phage LIBA6276, complete genome	50143-50176	0	1.0
NZ_CP045224_3	3.6\|779309\|34\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779309-779342	34	MF547663	Clostridioides phage LIBA2945, complete genome	49993-50026	0	1.0
NZ_CP045224_3	3.7\|779372\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779372-779407	36	LN681541	Clostridium phage phiMMP01, complete genome	36335-36370	0	1.0
NZ_CP045224_3	3.11\|779636\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779636-779672	37	MK473382	Clostridium phage JD032, complete genome	493-529	0	1.0
NZ_CP045224_3	3.12\|779702\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779702-779737	36	NC_048665	Clostridium phage phiCDHM14, complete genome	9236-9271	0	1.0
NZ_CP045224_3	3.12\|779702\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779702-779737	36	MK473382	Clostridium phage JD032, complete genome	25441-25476	0	1.0
NZ_CP045224_3	3.12\|779702\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779702-779737	36	JX145342	Clostridium phage phiMMP04, complete genome	9222-9257	0	1.0
NZ_CP045224_3	3.12\|779702\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779702-779737	36	NC_028838	Clostridium phage phiCD506, complete genome	9662-9697	0	1.0
NZ_CP045224_3	3.12\|779702\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779702-779737	36	HG796225	Clostridium phage phiCDHM13 complete genome	9204-9239	0	1.0
NZ_CP045224_3	3.12\|779702\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779702-779737	36	LN681538	Clostridium phage phiCD481-1, complete genome	9689-9724	0	1.0
NZ_CP045224_3	3.12\|779702\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779702-779737	36	HG798901	Clostridium phage phiCDHM11 complete genome	9203-9238	0	1.0
NZ_CP045224_3	3.13\|779767\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779767-779802	36	NC_048665	Clostridium phage phiCDHM14, complete genome	12408-12443	0	1.0
NZ_CP045224_3	3.13\|779767\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779767-779802	36	HG796225	Clostridium phage phiCDHM13 complete genome	12376-12411	0	1.0
NZ_CP045224_3	3.13\|779767\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779767-779802	36	HG798901	Clostridium phage phiCDHM11 complete genome	12375-12410	0	1.0
NZ_CP045224_3	3.13\|779767\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779767-779802	36	MK473382	Clostridium phage JD032, complete genome	22269-22304	0	1.0
NZ_CP045224_3	3.14\|779832\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779832-779867	36	NC_048665	Clostridium phage phiCDHM14, complete genome	27689-27724	0	1.0
NZ_CP045224_3	3.14\|779832\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779832-779867	36	JX145342	Clostridium phage phiMMP04, complete genome	26659-26694	0	1.0
NZ_CP045224_3	3.14\|779832\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779832-779867	36	HG796225	Clostridium phage phiCDHM13 complete genome	27723-27758	0	1.0
NZ_CP045224_3	3.14\|779832\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779832-779867	36	LN681538	Clostridium phage phiCD481-1, complete genome	27458-27493	0	1.0
NZ_CP045224_3	3.14\|779832\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779832-779867	36	HG798901	Clostridium phage phiCDHM11 complete genome	27720-27755	0	1.0
NZ_CP045224_3	3.17\|780031\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	780031-780067	37	NZ_CP029155	Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence	96659-96695	0	1.0
NZ_CP045224_3	3.17\|780031\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	780031-780067	37	MF547662	Clostridioides phage LIBA6276, complete genome	50512-50548	0	1.0
NZ_CP045224_3	3.17\|780031\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	780031-780067	37	MF547663	Clostridioides phage LIBA2945, complete genome	50362-50398	0	1.0
NZ_CP045224_3	3.17\|780031\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	780031-780067	37	JX145342	Clostridium phage phiMMP04, complete genome	16987-17023	0	1.0
NZ_CP045224_3	3.29\|780813\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	780813-780848	36	NC_028905	Clostridium phage phiCD111, complete genome	34736-34771	0	1.0
NZ_CP045224_3	3.30\|780878\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	780878-780914	37	NZ_CP020426	Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence	61044-61080	0	1.0
NZ_CP045224_3	3.30\|780878\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	780878-780914	37	MF547663	Clostridioides phage LIBA2945, complete genome	64508-64544	0	1.0
NZ_CP045224_3	3.30\|780878\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	780878-780914	37	CP011970	Peptoclostridium phage phiCDIF1296T strain DSM 1296, complete sequence	60920-60956	0	1.0
NZ_CP045224_3	3.30\|780878\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	780878-780914	37	LN681537	Clostridium phage phiCD211, complete genome	69782-69818	0	1.0
NZ_CP045224_7	7.2\|1069041\|35\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069041-1069075	35	HG531805	Clostridium phage CDMH1 complete genome	15144-15178	0	1.0
NZ_CP045224_7	7.6\|1069303\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069303-1069339	37	LN681539	Clostridium phage phiCD505, complete genome	46819-46855	0	1.0
NZ_CP045224_7	7.6\|1069303\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069303-1069339	37	LN681542	Clostridium phage phiMMP03, complete genome	48619-48655	0	1.0
NZ_CP045224_7	7.6\|1069303\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069303-1069339	37	NC_009231	Clostridium phage phiC2, complete genome	52157-52193	0	1.0
NZ_CP045224_7	7.6\|1069303\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069303-1069339	37	NC_011398	Clostridium phage phiCD27, complete genome	46118-46154	0	1.0
NZ_CP045224_7	7.6\|1069303\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069303-1069339	37	NC_048642	Clostridium phage CDKM9, complete genome	47263-47299	0	1.0
NZ_CP045224_7	7.10\|1069567\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069567-1069602	36	AY855346	Clostridium difficile bacteriophage phi CD119, complete genome	2395-2430	0	1.0
NZ_CP045224_7	7.10\|1069567\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069567-1069602	36	NC_007917	Clostridium phage phi CD119, complete genome	2395-2430	0	1.0
NZ_CP045224_7	7.10\|1069567\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069567-1069602	36	NC_028996	Clostridium phage phiCDHM19, complete genome	2642-2677	0	1.0
NZ_CP045224_7	7.14\|1069830\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069830-1069866	37	NZ_CP020425	Clostridioides difficile strain FDAARGOS_267 plasmid unnamed1, complete sequence	20608-20644	0	1.0
NZ_CP045224_7	7.14\|1069830\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069830-1069866	37	FN668942	Clostridium difficile BI1 plasmid pCDBI1, complete sequence	19253-19289	0	1.0
NZ_CP045224_7	7.14\|1069830\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069830-1069866	37	NZ_CP011969	Clostridioides difficile ATCC 9689 = DSM 1296 plasmid unnamed, complete sequence	15930-15966	0	1.0
NZ_CP045224_7	7.14\|1069830\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069830-1069866	37	HG531805	Clostridium phage CDMH1 complete genome	25917-25953	0	1.0
NZ_CP045224_7	7.16\|1069964\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069964-1070000	37	NC_011398	Clostridium phage phiCD27, complete genome	48599-48635	0	1.0
NZ_CP045224_7	7.17\|1070030\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070030-1070066	37	LN681542	Clostridium phage phiMMP03, complete genome	20289-20325	0	1.0
NZ_CP045224_7	7.17\|1070030\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070030-1070066	37	NC_009231	Clostridium phage phiC2, complete genome	20242-20278	0	1.0
NZ_CP045224_7	7.17\|1070030\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070030-1070066	37	LN681541	Clostridium phage phiMMP01, complete genome	20288-20324	0	1.0
NZ_CP045224_7	7.20\|1070227\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070227-1070262	36	NC_008226	Clostridioides difficile 630 plasmid pCD630, complete sequence	6558-6593	0	1.0
NZ_CP045224_7	7.20\|1070227\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070227-1070262	36	NZ_CP016319	Clostridioides difficile strain 630 delta erm plasmid pCD630, complete sequence	1579-1614	0	1.0
NZ_CP045224_7	7.24\|1070491\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070491-1070526	36	NC_048665	Clostridium phage phiCDHM14, complete genome	8812-8847	0	1.0
NZ_CP045224_7	7.24\|1070491\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070491-1070526	36	HG796225	Clostridium phage phiCDHM13 complete genome	8780-8815	0	1.0
NZ_CP045224_7	7.24\|1070491\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070491-1070526	36	HG798901	Clostridium phage phiCDHM11 complete genome	8779-8814	0	1.0
NZ_CP045224_7	7.24\|1070491\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070491-1070526	36	MK473382	Clostridium phage JD032, complete genome	25865-25900	0	1.0
NZ_CP045224_7	7.25\|1070556\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070556-1070592	37	MK473382	Clostridium phage JD032, complete genome	12222-12258	0	1.0
NZ_CP045224_7	7.27\|1070688\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070688-1070724	37	NC_028838	Clostridium phage phiCD506, complete genome	6223-6259	0	1.0
NZ_CP045224_7	7.27\|1070688\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070688-1070724	37	LN681538	Clostridium phage phiCD481-1, complete genome	6249-6285	0	1.0
NZ_CP045224_7	7.28\|1070754\|38\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070754-1070791	38	NZ_CP029156	Clostridioides difficile strain CD161 plasmid unnamed2, complete sequence	30916-30953	0	1.0
NZ_CP045224_7	7.28\|1070754\|38\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070754-1070791	38	NZ_CP029153	Clostridioides difficile strain CDT4 plasmid unnamed1, complete sequence	24960-24997	0	1.0
NZ_CP045224_7	7.28\|1070754\|38\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070754-1070791	38	MK473382	Clostridium phage JD032, complete genome	19287-19324	0	1.0
NZ_CP045224_7	7.28\|1070754\|38\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070754-1070791	38	JX145342	Clostridium phage phiMMP04, complete genome	15368-15405	0	1.0
NZ_CP045224_7	7.29\|1070821\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070821-1070856	36	NC_028838	Clostridium phage phiCD506, complete genome	6082-6117	0	1.0
NZ_CP045224_7	7.40\|1071546\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1071546-1071582	37	NC_048642	Clostridium phage CDKM9, complete genome	41013-41049	0	1.0
NZ_CP045224_7	7.41\|1071612\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1071612-1071648	37	NC_048642	Clostridium phage CDKM9, complete genome	41013-41049	0	1.0
NZ_CP045224_7	7.45\|1071876\|37\|NZ_CP045224\|CRISPRCasFinder,CRT	1071876-1071912	37	NZ_MF547664	Clostridioides difficile strain LIBA-6289 plasmid LIBA6289, complete sequence	66323-66359	0	1.0
NZ_CP045224_8	8.7\|1793487\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1793487-1793522	36	NZ_CP029155	Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence	106698-106733	0	1.0
NZ_CP045224_8	8.7\|1793487\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1793487-1793522	36	MF547662	Clostridioides phage LIBA6276, complete genome	60551-60586	0	1.0
NZ_CP045224_8	8.7\|1793487\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1793487-1793522	36	MF547663	Clostridioides phage LIBA2945, complete genome	60401-60436	0	1.0
NZ_CP045224_8	8.7\|1793487\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1793487-1793522	36	CP011970	Peptoclostridium phage phiCDIF1296T strain DSM 1296, complete sequence	52848-52883	0	1.0
NZ_CP045224_8	8.7\|1793487\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1793487-1793522	36	LN681537	Clostridium phage phiCD211, complete genome	61710-61745	0	1.0
NZ_CP045224_8	8.7\|1793487\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1793487-1793522	36	NZ_CP020426	Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence	69117-69152	0	1.0
NZ_CP045224_8	8.11\|1793750\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1793750-1793785	36	NZ_CP020426	Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence	99213-99248	0	1.0
NZ_CP045224_8	8.11\|1793750\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1793750-1793785	36	NZ_CP029155	Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence	77943-77978	0	1.0
NZ_CP045224_8	8.11\|1793750\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1793750-1793785	36	CP011970	Peptoclostridium phage phiCDIF1296T strain DSM 1296, complete sequence	22752-22787	0	1.0
NZ_CP045224_8	8.11\|1793750\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1793750-1793785	36	LN681537	Clostridium phage phiCD211, complete genome	31614-31649	0	1.0
NZ_CP045224_8	8.17\|1794143\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794143-1794178	36	NZ_CP020426	Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence	101810-101845	0	1.0
NZ_CP045224_8	8.17\|1794143\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794143-1794178	36	CP011970	Peptoclostridium phage phiCDIF1296T strain DSM 1296, complete sequence	20155-20190	0	1.0
NZ_CP045224_8	8.17\|1794143\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794143-1794178	36	LN681537	Clostridium phage phiCD211, complete genome	29017-29052	0	1.0
NZ_CP045224_8	8.18\|1794209\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794209-1794244	36	NZ_CP020426	Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence	102792-102827	0	1.0
NZ_CP045224_8	8.18\|1794209\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794209-1794244	36	NZ_CP029155	Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence	74441-74476	0	1.0
NZ_CP045224_8	8.18\|1794209\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794209-1794244	36	CP011970	Peptoclostridium phage phiCDIF1296T strain DSM 1296, complete sequence	19173-19208	0	1.0
NZ_CP045224_8	8.18\|1794209\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794209-1794244	36	LN681537	Clostridium phage phiCD211, complete genome	28035-28070	0	1.0
NZ_CP045224_8	8.19\|1794275\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794275-1794310	36	NZ_CP029155	Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence	74090-74125	0	1.0
NZ_CP045224_8	8.32\|1795134\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1795134-1795169	36	KU057941	Clostridium phage CDSH1, complete genome	21442-21477	0	1.0
NZ_CP045224_8	8.32\|1795134\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1795134-1795169	36	NC_028905	Clostridium phage phiCD111, complete genome	21182-21217	0	1.0
NZ_CP045224_8	8.32\|1795134\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1795134-1795169	36	HM568888	Clostridium phage phiCD38-2, complete genome	20938-20973	0	1.0
NZ_CP045224_8	8.32\|1795134\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1795134-1795169	36	NC_028958	Clostridium phage phiCD146, complete genome	20500-20535	0	1.0
NZ_CP045224_8	8.32\|1795134\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1795134-1795169	36	LN881738	Escherichia phage slur17, complete genome	40579-40614	0	1.0
NZ_CP045224_8	8.38\|1795528\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1795528-1795563	36	AY855346	Clostridium difficile bacteriophage phi CD119, complete genome	41065-41100	0	1.0
NZ_CP045224_8	8.38\|1795528\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1795528-1795563	36	NC_007917	Clostridium phage phi CD119, complete genome	41065-41100	0	1.0
NZ_CP045224_8	8.38\|1795528\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1795528-1795563	36	HG531805	Clostridium phage CDMH1 complete genome	43917-43952	0	1.0
NZ_CP045224_9	9.7\|1906247\|37\|NZ_CP045224\|PILER-CR	1906247-1906283	37	NZ_CP020425	Clostridioides difficile strain FDAARGOS_267 plasmid unnamed1, complete sequence	1757-1793	0	1.0
NZ_CP045224_9	9.7\|1906247\|37\|NZ_CP045224\|PILER-CR	1906247-1906283	37	FN668942	Clostridium difficile BI1 plasmid pCDBI1, complete sequence	420-456	0	1.0
NZ_CP045224_9	9.7\|1906247\|37\|NZ_CP045224\|PILER-CR	1906247-1906283	37	NZ_CP011969	Clostridioides difficile ATCC 9689 = DSM 1296 plasmid unnamed, complete sequence	42266-42302	0	1.0
NZ_CP045224_9	9.19\|1906248\|36\|NZ_CP045224\|CRISPRCasFinder,CRT	1906248-1906283	36	NZ_CP020425	Clostridioides difficile strain FDAARGOS_267 plasmid unnamed1, complete sequence	1757-1792	0	1.0
NZ_CP045224_9	9.19\|1906248\|36\|NZ_CP045224\|CRISPRCasFinder,CRT	1906248-1906283	36	FN668942	Clostridium difficile BI1 plasmid pCDBI1, complete sequence	420-455	0	1.0
NZ_CP045224_9	9.19\|1906248\|36\|NZ_CP045224\|CRISPRCasFinder,CRT	1906248-1906283	36	NZ_CP011969	Clostridioides difficile ATCC 9689 = DSM 1296 plasmid unnamed, complete sequence	42266-42301	0	1.0
NZ_CP045224_10	10.11\|2319449\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2319449-2319484	36	GU949551	Clostridium phage phiCD6356, complete genome	2657-2692	0	1.0
NZ_CP045224_10	10.15\|2319711\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2319711-2319747	37	AY855346	Clostridium difficile bacteriophage phi CD119, complete genome	34810-34846	0	1.0
NZ_CP045224_10	10.15\|2319711\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2319711-2319747	37	NC_007917	Clostridium phage phi CD119, complete genome	34810-34846	0	1.0
NZ_CP045224_10	10.15\|2319711\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2319711-2319747	37	LN681542	Clostridium phage phiMMP03, complete genome	35246-35282	0	1.0
NZ_CP045224_10	10.15\|2319711\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2319711-2319747	37	NC_009231	Clostridium phage phiC2, complete genome	38783-38819	0	1.0
NZ_CP045224_10	10.15\|2319711\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2319711-2319747	37	JX145341	Clostridium phage phiMMP02, complete genome	35766-35802	0	1.0
NZ_CP045224_10	10.15\|2319711\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2319711-2319747	37	LN681541	Clostridium phage phiMMP01, complete genome	32536-32572	0	1.0
NZ_CP045224_10	10.15\|2319711\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2319711-2319747	37	NC_011398	Clostridium phage phiCD27, complete genome	37556-37592	0	1.0
NZ_CP045224_10	10.15\|2319711\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2319711-2319747	37	NC_048642	Clostridium phage CDKM9, complete genome	36730-36766	0	1.0
NZ_CP045224_12	12.7\|2802740\|38\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2802740-2802777	38	NC_008226	Clostridioides difficile 630 plasmid pCD630, complete sequence	6216-6253	0	1.0
NZ_CP045224_12	12.7\|2802740\|38\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2802740-2802777	38	NZ_CP016319	Clostridioides difficile strain 630 delta erm plasmid pCD630, complete sequence	1237-1274	0	1.0
NZ_CP045224_12	12.8\|2802807\|38\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2802807-2802844	38	NZ_MG266000	Clostridioides difficile strain 7032985 plasmid pCD-ISS1, complete sequence	7213-7250	0	1.0
NZ_CP045224_14	14.1\|3936194\|28\|NZ_CP045224\|CRISPRCasFinder	3936194-3936221	28	NZ_CP033215	Clostridioides difficile strain 12038 plasmid unnamed1, complete sequence	5105-5132	0	1.0
NZ_CP045224_1	1.7\|337392\|22\|NZ_CP045224\|CRT	337392-337413	22	MK213796	Escherichia phage T1, complete genome	18173-18194	1	0.955
NZ_CP045224_1	1.7\|337392\|22\|NZ_CP045224\|CRT	337392-337413	22	NC_047785	Shigella phage SH6, complete genome	18870-18891	1	0.955
NZ_CP045224_1	1.7\|337392\|22\|NZ_CP045224\|CRT	337392-337413	22	MN153797	Escherichia virus T1 isolate 22, complete genome	18173-18194	1	0.955
NZ_CP045224_1	1.7\|337392\|22\|NZ_CP045224\|CRT	337392-337413	22	KU194206	Escherichia phage JMPW1, complete genome	19183-19204	1	0.955
NZ_CP045224_1	1.7\|337392\|22\|NZ_CP045224\|CRT	337392-337413	22	NC_041873	Escherichia phage JMPW2, complete genome	19131-19152	1	0.955
NZ_CP045224_1	1.7\|337392\|22\|NZ_CP045224\|CRT	337392-337413	22	JX912252	Escherichia phage ADB-2, complete genome	23136-23157	1	0.955
NZ_CP045224_1	1.7\|337392\|22\|NZ_CP045224\|CRT	337392-337413	22	NC_049831	Shigella virus Sfin-3, complete genome	15312-15333	1	0.955
NZ_CP045224_1	1.7\|337392\|22\|NZ_CP045224\|CRT	337392-337413	22	HM035024	Shigella phage Shfl1, complete genome	19535-19556	1	0.955
NZ_CP045224_1	1.7\|337392\|22\|NZ_CP045224\|CRT	337392-337413	22	MH917278	Shigella phage phi2457T, complete genome	19302-19323	1	0.955
NZ_CP045224_1	1.7\|337392\|22\|NZ_CP045224\|CRT	337392-337413	22	MT682715	Escherichia phage vB_EcoS_Chapo, complete genome	19208-19229	1	0.955
NZ_CP045224_1	1.7\|337392\|22\|NZ_CP045224\|CRT	337392-337413	22	KY985004	Escherichia phage vB_EcoS_SH2, complete genome	18697-18718	1	0.955
NZ_CP045224_1	1.7\|337392\|22\|NZ_CP045224\|CRT	337392-337413	22	NC_005833	Enterobacteria phage T1, complete genome	18173-18194	1	0.955
NZ_CP045224_1	1.7\|337392\|22\|NZ_CP045224\|CRT	337392-337413	22	KP085586	Shigella phage pSf-2, complete genome	25399-25420	1	0.955
NZ_CP045224_1	1.7\|337392\|22\|NZ_CP045224\|CRT	337392-337413	22	MH051912	Enterobacteria phage vB_EcoS_IME167, complete genome	30681-30702	1	0.955
NZ_CP045224_1	1.7\|337392\|22\|NZ_CP045224\|CRT	337392-337413	22	NC_049832	Escherichia phage vB_EcoS-DELF2 DNA, complete genome	47732-47753	1	0.955
NZ_CP045224_1	1.7\|337392\|22\|NZ_CP045224\|CRT	337392-337413	22	NC_041995	Shigella phage vB_SsoS-ISF002, complete genome	25720-25741	1	0.955
NZ_CP045224_3	3.2\|779049\|35\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779049-779083	35	NC_048642	Clostridium phage CDKM9, complete genome	41504-41538	1	0.971
NZ_CP045224_3	3.4\|779178\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779178-779213	36	LN681542	Clostridium phage phiMMP03, complete genome	20933-20968	1	0.972
NZ_CP045224_3	3.4\|779178\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779178-779213	36	HG531805	Clostridium phage CDMH1 complete genome	22030-22065	1	0.972
NZ_CP045224_3	3.4\|779178\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779178-779213	36	NC_009231	Clostridium phage phiC2, complete genome	20886-20921	1	0.972
NZ_CP045224_3	3.4\|779178\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779178-779213	36	LN681541	Clostridium phage phiMMP01, complete genome	20932-20967	1	0.972
NZ_CP045224_3	3.7\|779372\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779372-779407	36	AY855346	Clostridium difficile bacteriophage phi CD119, complete genome	37275-37310	1	0.972
NZ_CP045224_3	3.7\|779372\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779372-779407	36	NC_007917	Clostridium phage phi CD119, complete genome	37275-37310	1	0.972
NZ_CP045224_3	3.7\|779372\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779372-779407	36	LN681539	Clostridium phage phiCD505, complete genome	38774-38809	1	0.972
NZ_CP045224_3	3.7\|779372\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779372-779407	36	LN681542	Clostridium phage phiMMP03, complete genome	40017-40052	1	0.972
NZ_CP045224_3	3.7\|779372\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779372-779407	36	HG531805	Clostridium phage CDMH1 complete genome	40261-40296	1	0.972
NZ_CP045224_3	3.7\|779372\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779372-779407	36	NC_009231	Clostridium phage phiC2, complete genome	43554-43589	1	0.972
NZ_CP045224_3	3.7\|779372\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779372-779407	36	KX228400	Clostridium phage CDKM15, complete genome	40539-40574	1	0.972
NZ_CP045224_3	3.9\|779503\|38\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779503-779540	38	NC_028996	Clostridium phage phiCDHM19, complete genome	41368-41405	1	0.974
NZ_CP045224_3	3.11\|779636\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779636-779672	37	NC_008226	Clostridioides difficile 630 plasmid pCD630, complete sequence	5600-5636	1	0.973
NZ_CP045224_3	3.11\|779636\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779636-779672	37	NZ_CP016319	Clostridioides difficile strain 630 delta erm plasmid pCD630, complete sequence	621-657	1	0.973
NZ_CP045224_3	3.11\|779636\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779636-779672	37	NC_048665	Clostridium phage phiCDHM14, complete genome	31765-31801	1	0.973
NZ_CP045224_3	3.11\|779636\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779636-779672	37	NC_028838	Clostridium phage phiCD506, complete genome	32852-32888	1	0.973
NZ_CP045224_3	3.11\|779636\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779636-779672	37	HG796225	Clostridium phage phiCDHM13 complete genome	32715-32751	1	0.973
NZ_CP045224_3	3.11\|779636\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779636-779672	37	LN681538	Clostridium phage phiCD481-1, complete genome	32446-32482	1	0.973
NZ_CP045224_3	3.22\|780356\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	780356-780391	36	JX145342	Clostridium phage phiMMP04, complete genome	9722-9757	1	0.972
NZ_CP045224_3	3.26\|780616\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	780616-780652	37	NZ_CP029156	Clostridioides difficile strain CD161 plasmid unnamed2, complete sequence	27115-27151	1	0.973
NZ_CP045224_3	3.26\|780616\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	780616-780652	37	NZ_CP029153	Clostridioides difficile strain CDT4 plasmid unnamed1, complete sequence	21159-21195	1	0.973
NZ_CP045224_3	3.26\|780616\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	780616-780652	37	NC_048665	Clostridium phage phiCDHM14, complete genome	18138-18174	1	0.973
NZ_CP045224_3	3.26\|780616\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	780616-780652	37	HG796225	Clostridium phage phiCDHM13 complete genome	17638-17674	1	0.973
NZ_CP045224_3	3.26\|780616\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	780616-780652	37	HG798901	Clostridium phage phiCDHM11 complete genome	17637-17673	1	0.973
NZ_CP045224_3	3.30\|780878\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	780878-780914	37	NZ_CP029155	Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence	114752-114788	1	0.973
NZ_CP045224_7	7.2\|1069041\|35\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069041-1069075	35	LN681542	Clostridium phage phiMMP03, complete genome	14004-14038	1	0.971
NZ_CP045224_7	7.2\|1069041\|35\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069041-1069075	35	NC_009231	Clostridium phage phiC2, complete genome	14035-14069	1	0.971
NZ_CP045224_7	7.2\|1069041\|35\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069041-1069075	35	LN681541	Clostridium phage phiMMP01, complete genome	14004-14038	1	0.971
NZ_CP045224_7	7.4\|1069171\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069171-1069206	36	LN681539	Clostridium phage phiCD505, complete genome	36578-36613	1	0.972
NZ_CP045224_7	7.4\|1069171\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069171-1069206	36	LN681542	Clostridium phage phiMMP03, complete genome	36640-36675	1	0.972
NZ_CP045224_7	7.4\|1069171\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069171-1069206	36	NC_009231	Clostridium phage phiC2, complete genome	40177-40212	1	0.972
NZ_CP045224_7	7.4\|1069171\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069171-1069206	36	NC_048642	Clostridium phage CDKM9, complete genome	38124-38159	1	0.972
NZ_CP045224_7	7.5\|1069236\|38\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069236-1069273	38	LN681542	Clostridium phage phiMMP03, complete genome	15825-15862	1	0.974
NZ_CP045224_7	7.5\|1069236\|38\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069236-1069273	38	NC_009231	Clostridium phage phiC2, complete genome	15856-15893	1	0.974
NZ_CP045224_7	7.5\|1069236\|38\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069236-1069273	38	LN681541	Clostridium phage phiMMP01, complete genome	15825-15862	1	0.974
NZ_CP045224_7	7.14\|1069830\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069830-1069866	37	NC_048665	Clostridium phage phiCDHM14, complete genome	18934-18970	1	0.973
NZ_CP045224_7	7.14\|1069830\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069830-1069866	37	LN681539	Clostridium phage phiCD505, complete genome	28459-28495	1	0.973
NZ_CP045224_7	7.14\|1069830\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069830-1069866	37	JX145342	Clostridium phage phiMMP04, complete genome	18939-18975	1	0.973
NZ_CP045224_7	7.14\|1069830\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069830-1069866	37	LN681542	Clostridium phage phiMMP03, complete genome	27438-27474	1	0.973
NZ_CP045224_7	7.14\|1069830\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069830-1069866	37	NC_028838	Clostridium phage phiCD506, complete genome	19063-19099	1	0.973
NZ_CP045224_7	7.14\|1069830\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069830-1069866	37	HG796225	Clostridium phage phiCDHM13 complete genome	18434-18470	1	0.973
NZ_CP045224_7	7.14\|1069830\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069830-1069866	37	JX145341	Clostridium phage phiMMP02, complete genome	27690-27726	1	0.973
NZ_CP045224_7	7.14\|1069830\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069830-1069866	37	LN681541	Clostridium phage phiMMP01, complete genome	24681-24717	1	0.973
NZ_CP045224_7	7.14\|1069830\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069830-1069866	37	NC_011398	Clostridium phage phiCD27, complete genome	27974-28010	1	0.973
NZ_CP045224_7	7.14\|1069830\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069830-1069866	37	HG798901	Clostridium phage phiCDHM11 complete genome	18433-18469	1	0.973
NZ_CP045224_7	7.14\|1069830\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069830-1069866	37	KX228400	Clostridium phage CDKM15, complete genome	29839-29875	1	0.973
NZ_CP045224_7	7.22\|1070358\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070358-1070394	37	LN681539	Clostridium phage phiCD505, complete genome	25906-25942	1	0.973
NZ_CP045224_7	7.22\|1070358\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070358-1070394	37	LN681542	Clostridium phage phiMMP03, complete genome	24885-24921	1	0.973
NZ_CP045224_7	7.28\|1070754\|38\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070754-1070791	38	NZ_CP020425	Clostridioides difficile strain FDAARGOS_267 plasmid unnamed1, complete sequence	16703-16740	1	0.974
NZ_CP045224_7	7.28\|1070754\|38\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070754-1070791	38	FN668942	Clostridium difficile BI1 plasmid pCDBI1, complete sequence	15348-15385	1	0.974
NZ_CP045224_7	7.28\|1070754\|38\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070754-1070791	38	NZ_CP011969	Clostridioides difficile ATCC 9689 = DSM 1296 plasmid unnamed, complete sequence	12025-12062	1	0.974
NZ_CP045224_7	7.29\|1070821\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070821-1070856	36	LN681538	Clostridium phage phiCD481-1, complete genome	6108-6143	1	0.972
NZ_CP045224_7	7.32\|1071018\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1071018-1071054	37	NC_009231	Clostridium phage phiC2, complete genome	17675-17711	1	0.973
NZ_CP045224_8	8.2\|1793157\|36\|NZ_CP045224\|CRT,CRISPRCasFinder	1793157-1793192	36	NZ_CP020426	Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence	52293-52328	1	0.972
NZ_CP045224_8	8.2\|1793157\|36\|NZ_CP045224\|CRT,CRISPRCasFinder	1793157-1793192	36	NZ_CP029155	Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence	123047-123082	1	0.972
NZ_CP045224_8	8.2\|1793157\|36\|NZ_CP045224\|CRT,CRISPRCasFinder	1793157-1793192	36	CP011970	Peptoclostridium phage phiCDIF1296T strain DSM 1296, complete sequence	69672-69707	1	0.972
NZ_CP045224_8	8.2\|1793157\|36\|NZ_CP045224\|CRT,CRISPRCasFinder	1793157-1793192	36	LN681537	Clostridium phage phiCD211, complete genome	78534-78569	1	0.972
NZ_CP045224_8	8.8\|1793553\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1793553-1793588	36	NZ_CP029155	Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence	79416-79451	1	0.972
NZ_CP045224_8	8.16\|1794077\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794077-1794112	36	NZ_CP029155	Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence	78642-78677	1	0.972
NZ_CP045224_8	8.16\|1794077\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794077-1794112	36	CP011970	Peptoclostridium phage phiCDIF1296T strain DSM 1296, complete sequence	23451-23486	1	0.972
NZ_CP045224_8	8.16\|1794077\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794077-1794112	36	LN681537	Clostridium phage phiCD211, complete genome	32313-32348	1	0.972
NZ_CP045224_8	8.16\|1794077\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794077-1794112	36	NZ_CP020426	Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence	98514-98549	1	0.972
NZ_CP045224_8	8.19\|1794275\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794275-1794310	36	NZ_CP020426	Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence	103143-103178	1	0.972
NZ_CP045224_8	8.19\|1794275\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794275-1794310	36	CP011970	Peptoclostridium phage phiCDIF1296T strain DSM 1296, complete sequence	18822-18857	1	0.972
NZ_CP045224_8	8.19\|1794275\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794275-1794310	36	LN681537	Clostridium phage phiCD211, complete genome	27684-27719	1	0.972
NZ_CP045224_8	8.21\|1794408\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794408-1794443	36	GU949551	Clostridium phage phiCD6356, complete genome	36074-36109	1	0.972
NZ_CP045224_8	8.23\|1794540\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794540-1794575	36	NZ_CP020426	Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence	47983-48018	1	0.972
NZ_CP045224_8	8.23\|1794540\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794540-1794575	36	NZ_CP029155	Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence	125389-125424	1	0.972
NZ_CP045224_8	8.23\|1794540\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794540-1794575	36	CP011970	Peptoclostridium phage phiCDIF1296T strain DSM 1296, complete sequence	73982-74017	1	0.972
NZ_CP045224_8	8.23\|1794540\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794540-1794575	36	LN681537	Clostridium phage phiCD211, complete genome	82844-82879	1	0.972
NZ_CP045224_8	8.24\|1794606\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794606-1794641	36	NZ_CP029155	Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence	111280-111315	1	0.972
NZ_CP045224_8	8.24\|1794606\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794606-1794641	36	MF547662	Clostridioides phage LIBA6276, complete genome	64625-64660	1	0.972
NZ_CP045224_8	8.24\|1794606\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794606-1794641	36	CP011970	Peptoclostridium phage phiCDIF1296T strain DSM 1296, complete sequence	57448-57483	1	0.972
NZ_CP045224_8	8.24\|1794606\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794606-1794641	36	LN681537	Clostridium phage phiCD211, complete genome	66310-66345	1	0.972
NZ_CP045224_8	8.24\|1794606\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794606-1794641	36	NZ_CP020426	Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence	64517-64552	1	0.972
NZ_CP045224_8	8.37\|1795462\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1795462-1795497	36	NZ_MF547664	Clostridioides difficile strain LIBA-6289 plasmid LIBA6289, complete sequence	62659-62694	1	0.972
NZ_CP045224_8	8.38\|1795528\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1795528-1795563	36	LN681539	Clostridium phage phiCD505, complete genome	41179-41214	1	0.972
NZ_CP045224_9	9.7\|1906247\|37\|NZ_CP045224\|PILER-CR	1906247-1906283	37	NZ_CP029156	Clostridioides difficile strain CD161 plasmid unnamed2, complete sequence	45851-45887	1	0.973
NZ_CP045224_9	9.7\|1906247\|37\|NZ_CP045224\|PILER-CR	1906247-1906283	37	NZ_CP029153	Clostridioides difficile strain CDT4 plasmid unnamed1, complete sequence	39895-39931	1	0.973
NZ_CP045224_9	9.17\|1906118\|36\|NZ_CP045224\|CRISPRCasFinder,CRT	1906118-1906153	36	LN681539	Clostridium phage phiCD505, complete genome	49161-49196	1	0.972
NZ_CP045224_9	9.17\|1906118\|36\|NZ_CP045224\|CRISPRCasFinder,CRT	1906118-1906153	36	HG531805	Clostridium phage CDMH1 complete genome	51883-51918	1	0.972
NZ_CP045224_9	9.17\|1906118\|36\|NZ_CP045224\|CRISPRCasFinder,CRT	1906118-1906153	36	JX145341	Clostridium phage phiMMP02, complete genome	48240-48275	1	0.972
NZ_CP045224_9	9.17\|1906118\|36\|NZ_CP045224\|CRISPRCasFinder,CRT	1906118-1906153	36	NC_011398	Clostridium phage phiCD27, complete genome	50766-50801	1	0.972
NZ_CP045224_9	9.17\|1906118\|36\|NZ_CP045224\|CRISPRCasFinder,CRT	1906118-1906153	36	NC_048642	Clostridium phage CDKM9, complete genome	49605-49640	1	0.972
NZ_CP045224_9	9.19\|1906248\|36\|NZ_CP045224\|CRISPRCasFinder,CRT	1906248-1906283	36	NZ_CP029156	Clostridioides difficile strain CD161 plasmid unnamed2, complete sequence	45852-45887	1	0.972
NZ_CP045224_9	9.19\|1906248\|36\|NZ_CP045224\|CRISPRCasFinder,CRT	1906248-1906283	36	NZ_CP029153	Clostridioides difficile strain CDT4 plasmid unnamed1, complete sequence	39896-39931	1	0.972
NZ_CP045224_10	10.10\|2319383\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2319383-2319419	37	MK473382	Clostridium phage JD032, complete genome	35043-35079	1	0.973
NZ_CP045224_12	12.7\|2802740\|38\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2802740-2802777	38	NZ_MG266000	Clostridioides difficile strain 7032985 plasmid pCD-ISS1, complete sequence	6382-6419	1	0.974
NZ_CP045224_1	1.7\|337392\|22\|NZ_CP045224\|CRT	337392-337413	22	MH285980	Escherichia phage Eco_BIFF, complete genome	8915-8936	2	0.909
NZ_CP045224_1	1.7\|337392\|22\|NZ_CP045224\|CRT	337392-337413	22	NZ_LT969521	Pseudomonas aeruginosa isolate RW109 genome assembly, plasmid: RW109 plasmid 2	59024-59045	2	0.909
NZ_CP045224_1	1.7\|337392\|22\|NZ_CP045224\|CRT	337392-337413	22	NC_047959	Enterobacteria phage vB_EcoS_IME18, complete genome	46594-46615	2	0.909
NZ_CP045224_3	3.3\|779113\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779113-779148	36	LN681539	Clostridium phage phiCD505, complete genome	33801-33836	2	0.944
NZ_CP045224_3	3.3\|779113\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779113-779148	36	JX145341	Clostridium phage phiMMP02, complete genome	33030-33065	2	0.944
NZ_CP045224_3	3.6\|779309\|34\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779309-779342	34	LN681538	Clostridium phage phiCD481-1, complete genome	17348-17381	2	0.941
NZ_CP045224_3	3.7\|779372\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779372-779407	36	NC_028996	Clostridium phage phiCDHM19, complete genome	41037-41072	2	0.944
NZ_CP045224_3	3.7\|779372\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779372-779407	36	JX145341	Clostridium phage phiMMP02, complete genome	38199-38234	2	0.944
NZ_CP045224_3	3.8\|779437\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779437-779473	37	AY855346	Clostridium difficile bacteriophage phi CD119, complete genome	21499-21535	2	0.946
NZ_CP045224_3	3.8\|779437\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779437-779473	37	NC_048665	Clostridium phage phiCDHM14, complete genome	14654-14690	2	0.946
NZ_CP045224_3	3.8\|779437\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779437-779473	37	NC_007917	Clostridium phage phi CD119, complete genome	21499-21535	2	0.946
NZ_CP045224_3	3.8\|779437\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779437-779473	37	NC_028996	Clostridium phage phiCDHM19, complete genome	21752-21788	2	0.946
NZ_CP045224_3	3.8\|779437\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779437-779473	37	MK473382	Clostridium phage JD032, complete genome	20019-20055	2	0.946
NZ_CP045224_3	3.8\|779437\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779437-779473	37	HG796225	Clostridium phage phiCDHM13 complete genome	14622-14658	2	0.946
NZ_CP045224_3	3.8\|779437\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779437-779473	37	LN681538	Clostridium phage phiCD481-1, complete genome	15110-15146	2	0.946
NZ_CP045224_3	3.8\|779437\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779437-779473	37	HG798901	Clostridium phage phiCDHM11 complete genome	14621-14657	2	0.946
NZ_CP045224_3	3.25\|780551\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	780551-780586	36	GU949551	Clostridium phage phiCD6356, complete genome	10970-11005	2	0.944
NZ_CP045224_3	3.27\|780682\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	780682-780718	37	AY855346	Clostridium difficile bacteriophage phi CD119, complete genome	40544-40580	2	0.946
NZ_CP045224_3	3.27\|780682\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	780682-780718	37	NC_007917	Clostridium phage phi CD119, complete genome	40544-40580	2	0.946
NZ_CP045224_3	3.27\|780682\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	780682-780718	37	HG531805	Clostridium phage CDMH1 complete genome	43397-43433	2	0.946
NZ_CP045224_7	7.1\|1068974\|38\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1068974-1069011	38	NC_011398	Clostridium phage phiCD27, complete genome	49299-49336	2	0.947
NZ_CP045224_7	7.5\|1069236\|38\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069236-1069273	38	HG531805	Clostridium phage CDMH1 complete genome	17018-17055	2	0.947
NZ_CP045224_7	7.14\|1069830\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069830-1069866	37	MN718463	Clostridium phage phiCDKH01, complete genome	4382-4418	2	0.946
NZ_CP045224_7	7.14\|1069830\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069830-1069866	37	NC_048642	Clostridium phage CDKM9, complete genome	26661-26697	2	0.946
NZ_CP045224_7	7.28\|1070754\|38\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070754-1070791	38	NC_048665	Clostridium phage phiCDHM14, complete genome	15385-15422	2	0.947
NZ_CP045224_7	7.28\|1070754\|38\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070754-1070791	38	HG796225	Clostridium phage phiCDHM13 complete genome	15353-15390	2	0.947
NZ_CP045224_7	7.28\|1070754\|38\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070754-1070791	38	HG798901	Clostridium phage phiCDHM11 complete genome	15352-15389	2	0.947
NZ_CP045224_7	7.29\|1070821\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070821-1070856	36	MK473382	Clostridium phage JD032, complete genome	29020-29055	2	0.944
NZ_CP045224_7	7.29\|1070821\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070821-1070856	36	NC_048665	Clostridium phage phiCDHM14, complete genome	5624-5659	2	0.944
NZ_CP045224_7	7.29\|1070821\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070821-1070856	36	HG796225	Clostridium phage phiCDHM13 complete genome	5625-5660	2	0.944
NZ_CP045224_7	7.29\|1070821\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070821-1070856	36	HG798901	Clostridium phage phiCDHM11 complete genome	5624-5659	2	0.944
NZ_CP045224_7	7.37\|1071348\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1071348-1071383	36	KX905163	Clostridioides phage phiSemix9P1, complete genome	16013-16048	2	0.944
NZ_CP045224_8	8.3\|1793223\|36\|NZ_CP045224\|CRT,CRISPRCasFinder	1793223-1793258	36	CP011970	Peptoclostridium phage phiCDIF1296T strain DSM 1296, complete sequence	33780-33815	2	0.944
NZ_CP045224_8	8.3\|1793223\|36\|NZ_CP045224\|CRT,CRISPRCasFinder	1793223-1793258	36	LN681537	Clostridium phage phiCD211, complete genome	42642-42677	2	0.944
NZ_CP045224_8	8.3\|1793223\|36\|NZ_CP045224\|CRT,CRISPRCasFinder	1793223-1793258	36	NZ_CP020426	Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence	88185-88220	2	0.944
NZ_CP045224_8	8.8\|1793553\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1793553-1793588	36	CP011970	Peptoclostridium phage phiCDIF1296T strain DSM 1296, complete sequence	24225-24260	2	0.944
NZ_CP045224_8	8.8\|1793553\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1793553-1793588	36	LN681537	Clostridium phage phiCD211, complete genome	33087-33122	2	0.944
NZ_CP045224_8	8.8\|1793553\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1793553-1793588	36	NZ_CP020426	Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence	97740-97775	2	0.944
NZ_CP045224_8	8.24\|1794606\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794606-1794641	36	MF547663	Clostridioides phage LIBA2945, complete genome	63090-63125	2	0.944
NZ_CP045224_9	9.5\|1906117\|37\|NZ_CP045224\|PILER-CR	1906117-1906153	37	LN681539	Clostridium phage phiCD505, complete genome	49160-49196	2	0.946
NZ_CP045224_9	9.5\|1906117\|37\|NZ_CP045224\|PILER-CR	1906117-1906153	37	HG531805	Clostridium phage CDMH1 complete genome	51882-51918	2	0.946
NZ_CP045224_9	9.5\|1906117\|37\|NZ_CP045224\|PILER-CR	1906117-1906153	37	JX145341	Clostridium phage phiMMP02, complete genome	48239-48275	2	0.946
NZ_CP045224_9	9.5\|1906117\|37\|NZ_CP045224\|PILER-CR	1906117-1906153	37	NC_011398	Clostridium phage phiCD27, complete genome	50765-50801	2	0.946
NZ_CP045224_9	9.5\|1906117\|37\|NZ_CP045224\|PILER-CR	1906117-1906153	37	NC_048642	Clostridium phage CDKM9, complete genome	49604-49640	2	0.946
NZ_CP045224_9	9.20\|1906313\|37\|NZ_CP045224\|CRISPRCasFinder,CRT	1906313-1906349	37	NC_048665	Clostridium phage phiCDHM14, complete genome	13309-13345	2	0.946
NZ_CP045224_9	9.20\|1906313\|37\|NZ_CP045224\|CRISPRCasFinder,CRT	1906313-1906349	37	MK473382	Clostridium phage JD032, complete genome	21367-21403	2	0.946
NZ_CP045224_9	9.20\|1906313\|37\|NZ_CP045224\|CRISPRCasFinder,CRT	1906313-1906349	37	HG796225	Clostridium phage phiCDHM13 complete genome	13277-13313	2	0.946
NZ_CP045224_9	9.20\|1906313\|37\|NZ_CP045224\|CRISPRCasFinder,CRT	1906313-1906349	37	HG798901	Clostridium phage phiCDHM11 complete genome	13276-13312	2	0.946
NZ_CP045224_10	10.9\|2319317\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2319317-2319353	37	NC_048665	Clostridium phage phiCDHM14, complete genome	205-241	2	0.946
NZ_CP045224_10	10.9\|2319317\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2319317-2319353	37	JX145342	Clostridium phage phiMMP04, complete genome	226-262	2	0.946
NZ_CP045224_10	10.9\|2319317\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2319317-2319353	37	HG796225	Clostridium phage phiCDHM13 complete genome	205-241	2	0.946
NZ_CP045224_10	10.9\|2319317\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2319317-2319353	37	HG798901	Clostridium phage phiCDHM11 complete genome	205-241	2	0.946
NZ_CP045224_10	10.10\|2319383\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2319383-2319419	37	NC_048665	Clostridium phage phiCDHM14, complete genome	32247-32283	2	0.946
NZ_CP045224_10	10.10\|2319383\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2319383-2319419	37	JX145342	Clostridium phage phiMMP04, complete genome	31297-31333	2	0.946
NZ_CP045224_10	10.10\|2319383\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2319383-2319419	37	NC_028838	Clostridium phage phiCD506, complete genome	60-96	2	0.946
NZ_CP045224_10	10.10\|2319383\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2319383-2319419	37	HG796225	Clostridium phage phiCDHM13 complete genome	33197-33233	2	0.946
NZ_CP045224_10	10.10\|2319383\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2319383-2319419	37	LN681538	Clostridium phage phiCD481-1, complete genome	83-119	2	0.946
NZ_CP045224_10	10.10\|2319383\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2319383-2319419	37	HG798901	Clostridium phage phiCDHM11 complete genome	31600-31636	2	0.946
NZ_CP045224_10	10.14\|2319646\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2319646-2319681	36	JX145342	Clostridium phage phiMMP04, complete genome	27308-27343	2	0.944
NZ_CP045224_10	10.16\|2319777\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2319777-2319813	37	LN681539	Clostridium phage phiCD505, complete genome	32018-32054	2	0.946
NZ_CP045224_12	12.5\|2802607\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2802607-2802643	37	NZ_CP020425	Clostridioides difficile strain FDAARGOS_267 plasmid unnamed1, complete sequence	26227-26263	2	0.946
NZ_CP045224_12	12.5\|2802607\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2802607-2802643	37	NZ_CP029156	Clostridioides difficile strain CD161 plasmid unnamed2, complete sequence	20514-20550	2	0.946
NZ_CP045224_12	12.5\|2802607\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2802607-2802643	37	NZ_CP029153	Clostridioides difficile strain CDT4 plasmid unnamed1, complete sequence	14558-14594	2	0.946
NZ_CP045224_12	12.5\|2802607\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2802607-2802643	37	FN668942	Clostridium difficile BI1 plasmid pCDBI1, complete sequence	24872-24908	2	0.946
NZ_CP045224_12	12.5\|2802607\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2802607-2802643	37	NZ_CP011969	Clostridioides difficile ATCC 9689 = DSM 1296 plasmid unnamed, complete sequence	21549-21585	2	0.946
NZ_CP045224_12	12.8\|2802807\|38\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2802807-2802844	38	NC_008226	Clostridioides difficile 630 plasmid pCD630, complete sequence	7047-7084	2	0.947
NZ_CP045224_12	12.8\|2802807\|38\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2802807-2802844	38	NZ_CP016319	Clostridioides difficile strain 630 delta erm plasmid pCD630, complete sequence	2068-2105	2	0.947
NZ_CP045224_15	15.1\|4054099\|38\|NZ_CP045224\|CRISPRCasFinder	4054099-4054136	38	NZ_CP033215	Clostridioides difficile strain 12038 plasmid unnamed1, complete sequence	3094-3131	2	0.947
NZ_CP045224_1	1.7\|337392\|22\|NZ_CP045224\|CRT	337392-337413	22	NC_028998	Phormidium phage MIS-PhV1B, complete genome	7436-7457	3	0.864
NZ_CP045224_2	2.14\|455268\|27\|NZ_CP045224\|CRT	455268-455294	27	MN693816	Marine virus AFVG_250M124, complete genome	30618-30644	3	0.889
NZ_CP045224_3	3.8\|779437\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779437-779473	37	JX145342	Clostridium phage phiMMP04, complete genome	14637-14673	3	0.919
NZ_CP045224_3	3.8\|779437\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779437-779473	37	NC_028838	Clostridium phage phiCD506, complete genome	15083-15119	3	0.919
NZ_CP045224_3	3.19\|780162\|35\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	780162-780196	35	NZ_CP020426	Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence	74943-74977	3	0.914
NZ_CP045224_3	3.19\|780162\|35\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	780162-780196	35	NZ_CP029155	Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence	99230-99264	3	0.914
NZ_CP045224_3	3.19\|780162\|35\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	780162-780196	35	MF547662	Clostridioides phage LIBA6276, complete genome	53083-53117	3	0.914
NZ_CP045224_3	3.19\|780162\|35\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	780162-780196	35	MF547663	Clostridioides phage LIBA2945, complete genome	52933-52967	3	0.914
NZ_CP045224_3	3.19\|780162\|35\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	780162-780196	35	CP011970	Peptoclostridium phage phiCDIF1296T strain DSM 1296, complete sequence	47023-47057	3	0.914
NZ_CP045224_3	3.19\|780162\|35\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	780162-780196	35	LN681537	Clostridium phage phiCD211, complete genome	55885-55919	3	0.914
NZ_CP045224_7	7.19\|1070163\|35\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070163-1070197	35	AY855346	Clostridium difficile bacteriophage phi CD119, complete genome	12603-12637	3	0.914
NZ_CP045224_7	7.19\|1070163\|35\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070163-1070197	35	NC_007917	Clostridium phage phi CD119, complete genome	12603-12637	3	0.914
NZ_CP045224_7	7.19\|1070163\|35\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070163-1070197	35	NC_028996	Clostridium phage phiCDHM19, complete genome	12848-12882	3	0.914
NZ_CP045224_8	8.21\|1794408\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794408-1794443	36	NC_028838	Clostridium phage phiCD506, complete genome	31845-31880	3	0.917
NZ_CP045224_8	8.25\|1794672\|37\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794672-1794708	37	NZ_CP029155	Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence	103288-103324	3	0.919
NZ_CP045224_8	8.25\|1794672\|37\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794672-1794708	37	MF547662	Clostridioides phage LIBA6276, complete genome	57141-57177	3	0.919
NZ_CP045224_8	8.25\|1794672\|37\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794672-1794708	37	MF547663	Clostridioides phage LIBA2945, complete genome	56991-57027	3	0.919
NZ_CP045224_9	9.3\|1905986\|39\|NZ_CP045224\|PILER-CR	1905986-1906024	39	AY855346	Clostridium difficile bacteriophage phi CD119, complete genome	37528-37566	3	0.923
NZ_CP045224_9	9.3\|1905986\|39\|NZ_CP045224\|PILER-CR	1905986-1906024	39	NC_007917	Clostridium phage phi CD119, complete genome	37528-37566	3	0.923
NZ_CP045224_9	9.3\|1905986\|39\|NZ_CP045224\|PILER-CR	1905986-1906024	39	NC_028996	Clostridium phage phiCDHM19, complete genome	41290-41328	3	0.923
NZ_CP045224_9	9.3\|1905986\|39\|NZ_CP045224\|PILER-CR	1905986-1906024	39	LN681542	Clostridium phage phiMMP03, complete genome	40270-40308	3	0.923
NZ_CP045224_9	9.3\|1905986\|39\|NZ_CP045224\|PILER-CR	1905986-1906024	39	NC_009231	Clostridium phage phiC2, complete genome	43807-43845	3	0.923
NZ_CP045224_9	9.3\|1905986\|39\|NZ_CP045224\|PILER-CR	1905986-1906024	39	JX145341	Clostridium phage phiMMP02, complete genome	38452-38490	3	0.923
NZ_CP045224_9	9.3\|1905986\|39\|NZ_CP045224\|PILER-CR	1905986-1906024	39	NC_011398	Clostridium phage phiCD27, complete genome	39277-39315	3	0.923
NZ_CP045224_9	9.3\|1905986\|39\|NZ_CP045224\|PILER-CR	1905986-1906024	39	KX228400	Clostridium phage CDKM15, complete genome	40792-40830	3	0.923
NZ_CP045224_9	9.8\|1906312\|38\|NZ_CP045224\|PILER-CR	1906312-1906349	38	MK473382	Clostridium phage JD032, complete genome	21367-21404	3	0.921
NZ_CP045224_9	9.8\|1906312\|38\|NZ_CP045224\|PILER-CR	1906312-1906349	38	NC_048665	Clostridium phage phiCDHM14, complete genome	13308-13345	3	0.921
NZ_CP045224_9	9.8\|1906312\|38\|NZ_CP045224\|PILER-CR	1906312-1906349	38	HG796225	Clostridium phage phiCDHM13 complete genome	13276-13313	3	0.921
NZ_CP045224_9	9.8\|1906312\|38\|NZ_CP045224\|PILER-CR	1906312-1906349	38	HG798901	Clostridium phage phiCDHM11 complete genome	13275-13312	3	0.921
NZ_CP045224_9	9.15\|1905987\|38\|NZ_CP045224\|CRISPRCasFinder,CRT	1905987-1906024	38	AY855346	Clostridium difficile bacteriophage phi CD119, complete genome	37529-37566	3	0.921
NZ_CP045224_9	9.15\|1905987\|38\|NZ_CP045224\|CRISPRCasFinder,CRT	1905987-1906024	38	NC_007917	Clostridium phage phi CD119, complete genome	37529-37566	3	0.921
NZ_CP045224_9	9.15\|1905987\|38\|NZ_CP045224\|CRISPRCasFinder,CRT	1905987-1906024	38	NC_028996	Clostridium phage phiCDHM19, complete genome	41291-41328	3	0.921
NZ_CP045224_9	9.15\|1905987\|38\|NZ_CP045224\|CRISPRCasFinder,CRT	1905987-1906024	38	LN681542	Clostridium phage phiMMP03, complete genome	40271-40308	3	0.921
NZ_CP045224_9	9.15\|1905987\|38\|NZ_CP045224\|CRISPRCasFinder,CRT	1905987-1906024	38	NC_009231	Clostridium phage phiC2, complete genome	43808-43845	3	0.921
NZ_CP045224_9	9.15\|1905987\|38\|NZ_CP045224\|CRISPRCasFinder,CRT	1905987-1906024	38	JX145341	Clostridium phage phiMMP02, complete genome	38453-38490	3	0.921
NZ_CP045224_9	9.15\|1905987\|38\|NZ_CP045224\|CRISPRCasFinder,CRT	1905987-1906024	38	NC_011398	Clostridium phage phiCD27, complete genome	39278-39315	3	0.921
NZ_CP045224_9	9.15\|1905987\|38\|NZ_CP045224\|CRISPRCasFinder,CRT	1905987-1906024	38	KX228400	Clostridium phage CDKM15, complete genome	40793-40830	3	0.921
NZ_CP045224_12	12.2\|2802409\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2802409-2802445	37	GU949551	Clostridium phage phiCD6356, complete genome	34408-34444	3	0.919
NZ_CP045224_12	12.4\|2802541\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2802541-2802577	37	NC_005326	[Clostridium] difficile plasmid pCD6, complete sequence	6388-6424	3	0.919
NZ_CP045224_10	10.8\|2319251\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2319251-2319287	37	NC_009231	Clostridium phage phiC2, complete genome	25925-25961	4	0.892
NZ_CP045224_10	10.9\|2319317\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2319317-2319353	37	MK473382	Clostridium phage JD032, complete genome	34438-34474	4	0.892
NZ_CP045224_10	10.9\|2319317\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2319317-2319353	37	NC_028838	Clostridium phage phiCD506, complete genome	665-701	4	0.892
NZ_CP045224_10	10.9\|2319317\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2319317-2319353	37	LN681538	Clostridium phage phiCD481-1, complete genome	688-724	4	0.892
NZ_CP045224_13	13.5\|3182527\|30\|NZ_CP045224\|CRISPRCasFinder	3182527-3182556	30	NZ_CP012644	Rufibacter tibetensis strain 1351 plasmid 1, complete sequence	141401-141430	4	0.867
NZ_CP045224_1	1.6\|337347\|25\|NZ_CP045224\|CRT	337347-337371	25	CP011076	Brevibacillus laterosporus strain B9 plasmid unnamed2, complete sequence	252018-252042	5	0.8
NZ_CP045224_1	1.6\|337347\|25\|NZ_CP045224\|CRT	337347-337371	25	NZ_CP014284	Bacillus thuringiensis strain Bt185 plasmid pBT1850294, complete sequence	179067-179091	5	0.8
NZ_CP045224_1	1.6\|337347\|25\|NZ_CP045224\|CRT	337347-337371	25	NZ_CP032609	Bacillus thuringiensis strain QZL38 plasmid p.2, complete sequence	270968-270992	5	0.8
NZ_CP045224_2	2.11\|455133\|27\|NZ_CP045224\|CRT	455133-455159	27	MN480762	Streptococcus salivarius strain NU10 plasmid pSsal-NU10, complete sequence	176920-176946	5	0.815
NZ_CP045224_3	3.15\|779897\|39\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779897-779935	39	NZ_CP020425	Clostridioides difficile strain FDAARGOS_267 plasmid unnamed1, complete sequence	20149-20187	5	0.872
NZ_CP045224_3	3.15\|779897\|39\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779897-779935	39	FN668942	Clostridium difficile BI1 plasmid pCDBI1, complete sequence	18794-18832	5	0.872
NZ_CP045224_3	3.15\|779897\|39\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779897-779935	39	NZ_CP011969	Clostridioides difficile ATCC 9689 = DSM 1296 plasmid unnamed, complete sequence	15471-15509	5	0.872
NZ_CP045224_7	7.3\|1069105\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069105-1069141	37	HG531805	Clostridium phage CDMH1 complete genome	20853-20889	5	0.865
NZ_CP045224_7	7.24\|1070491\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070491-1070526	36	JX145342	Clostridium phage phiMMP04, complete genome	8798-8833	5	0.861
NZ_CP045224_10	10.1\|2318788\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2318788-2318823	36	MK473382	Clostridium phage JD032, complete genome	34535-34570	5	0.861
NZ_CP045224_2	2.9\|455034\|27\|NZ_CP045224\|CRT	455034-455060	27	NZ_CP023312	Vibrio anguillarum strain VIB12 isolate Sea bass plasmid p292, complete sequence	259440-259466	6	0.778
NZ_CP045224_2	2.15\|455313\|36\|NZ_CP045224\|CRT	455313-455348	36	CP011076	Brevibacillus laterosporus strain B9 plasmid unnamed2, complete sequence	251929-251964	6	0.833
NZ_CP045224_3	3.8\|779437\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779437-779473	37	NZ_CP020425	Clostridioides difficile strain FDAARGOS_267 plasmid unnamed1, complete sequence	15975-16011	6	0.838
NZ_CP045224_3	3.8\|779437\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779437-779473	37	FN668942	Clostridium difficile BI1 plasmid pCDBI1, complete sequence	14620-14656	6	0.838
NZ_CP045224_3	3.8\|779437\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779437-779473	37	NZ_CP011969	Clostridioides difficile ATCC 9689 = DSM 1296 plasmid unnamed, complete sequence	11297-11333	6	0.838
NZ_CP045224_3	3.24\|780486\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	780486-780521	36	MK473382	Clostridium phage JD032, complete genome	6548-6583	6	0.833
NZ_CP045224_7	7.14\|1069830\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1069830-1069866	37	MK473382	Clostridium phage JD032, complete genome	15449-15485	6	0.838
NZ_CP045224_13	13.3\|3182395\|30\|NZ_CP045224\|CRISPRCasFinder	3182395-3182424	30	NZ_CP040675	Exiguobacterium mexicanum strain A-EM plasmid punnamed1, complete sequence	7748-7777	6	0.8
NZ_CP045224_14	14.1\|3936194\|28\|NZ_CP045224\|CRISPRCasFinder	3936194-3936221	28	KY971610	Pseudomonas phage PspYZU05, complete genome	134240-134267	6	0.786
NZ_CP045224_2	2.9\|455034\|27\|NZ_CP045224\|CRT	455034-455060	27	AP014366	Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S41-C63, * SEQUENCING IN PROGRESS *	24598-24624	7	0.741
NZ_CP045224_7	7.43\|1071744\|37\|NZ_CP045224\|CRISPRCasFinder,CRT	1071744-1071780	37	NZ_CP013206	Paenibacillus sp. IHB B 3084 plasmid pHD03, complete sequence	39283-39319	7	0.811
NZ_CP045224_8	8.10\|1793685\|35\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1793685-1793719	35	MN855865	Myoviridae sp. isolate 346, complete genome	2209-2243	7	0.8
NZ_CP045224_12	12.2\|2802409\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2802409-2802445	37	NZ_CP043618	Sulfurimonas sp. GYSZ_1 plasmid unnamed, complete sequence	3662-3698	7	0.811
NZ_CP045224_12	12.2\|2802409\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2802409-2802445	37	NZ_CP043618	Sulfurimonas sp. GYSZ_1 plasmid unnamed, complete sequence	32895-32931	7	0.811
NZ_CP045224_13	13.4\|3182461\|30\|NZ_CP045224\|CRISPRCasFinder	3182461-3182490	30	HM452126	Aeromonas phage phiAS5, complete genome	188022-188051	7	0.767
NZ_CP045224_13	13.7\|3182659\|30\|NZ_CP045224\|CRISPRCasFinder	3182659-3182688	30	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	60200-60229	7	0.767
NZ_CP045224_13	13.8\|3182725\|30\|NZ_CP045224\|CRISPRCasFinder	3182725-3182754	30	NZ_CP015323	Bacillus filamentosus strain Hbe603 plasmid pBEH1, complete sequence	34052-34081	7	0.767
NZ_CP045224_13	13.8\|3182725\|30\|NZ_CP045224\|CRISPRCasFinder	3182725-3182754	30	NC_025171	Acinetobacter sp. M131 plasmid pM131-5, complete sequence	4697-4726	7	0.767
NZ_CP045224_2	2.10\|455079\|36\|NZ_CP045224\|CRT	455079-455114	36	CP011076	Brevibacillus laterosporus strain B9 plasmid unnamed2, complete sequence	251929-251964	8	0.778
NZ_CP045224_2	2.10\|455079\|36\|NZ_CP045224\|CRT	455079-455114	36	KF437907	Phormidium phage MIS-PhV1A, complete genome	8690-8725	8	0.778
NZ_CP045224_7	7.24\|1070491\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070491-1070526	36	NC_013944	Staphylococcus simulans bv. staphylolyticus strain NRRL B-2628 plasmid pACK1, complete sequence	26064-26099	8	0.778
NZ_CP045224_7	7.24\|1070491\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070491-1070526	36	NC_013945	Staphylococcus simulans bv. staphylolyticus strain NRRL B-2628 plasmid pACK3, complete sequence	26064-26099	8	0.778
NZ_CP045224_8	8.10\|1793685\|35\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1793685-1793719	35	NC_017736	Helicobacter cetorum MIT 99-5656 plasmid pHCD, complete sequence	8468-8502	8	0.771
NZ_CP045224_8	8.10\|1793685\|35\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1793685-1793719	35	NC_017736	Helicobacter cetorum MIT 99-5656 plasmid pHCD, complete sequence	8705-8739	8	0.771
NZ_CP045224_8	8.27\|1794805\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794805-1794840	36	MH884511	Exiguobacterium phage vB_EalM-132, complete genome	57668-57703	8	0.778
NZ_CP045224_8	8.37\|1795462\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1795462-1795497	36	NZ_CP007513	Bacillus bombysepticus plasmid pBb, complete genome	32365-32400	8	0.778
NZ_CP045224_8	8.37\|1795462\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1795462-1795497	36	CP046512	Bacillus cereus strain JHU plasmid p1, complete sequence	393669-393704	8	0.778
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	AP013453	Uncultured Mediterranean phage uvMED DNA, complete genome, group G17, isolate: uvMED-CGR-U-MedDCM-OCT-S28-C28	9566-9597	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NZ_CP025426	Enterococcus faecium strain SC4 plasmid p1, complete sequence	150973-151004	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	LT603679	Enterococcus faecium isolate Ef_DMG1500501 genome assembly, plasmid: 2	68291-68322	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NZ_CP040369	Enterococcus faecium strain VB3240 plasmid unnamed1, complete sequence	111143-111174	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NZ_CP043485	Enterococcus faecium strain DMEA02 plasmid pDMEA1, complete sequence	100671-100702	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NZ_CP020485	Enterococcus faecium strain CFSAN059070 plasmid unnamed1, complete sequence	23887-23918	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NZ_CP013995	Enterococcus faecium strain 6E6 plasmid unnamed1, complete sequence	118355-118386	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NZ_CP027518	Enterococcus faecium strain AUSMDU00004024 plasmid unnamed1, complete sequence	144805-144836	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NZ_CP027498	Enterococcus faecium strain AUSMDU00004167 plasmid unnamed1, complete sequence	66860-66891	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NZ_CP027507	Enterococcus faecium strain AUSMDU00004055 plasmid unnamed1, complete sequence	44298-44329	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NZ_CP046076	Enterococcus faecium strain VRE plasmid p5_03A17012, complete sequence	140254-140285	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NZ_LR135236	Enterococcus faecium isolate E7067 plasmid 2	73999-74030	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NZ_CP019209	Enterococcus faecium strain 2014-VREF-41 plasmid p41-1, complete sequence	175685-175716	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NZ_LR135429	Enterococcus faecium isolate E8927 plasmid 2	97410-97441	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NZ_LR135476	Enterococcus faecium isolate E8423 plasmid 2	145680-145711	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NZ_LR135220	Enterococcus faecium isolate E7040 plasmid 2	74349-74380	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NZ_LR135358	Enterococcus faecium isolate E7948 plasmid 2	162261-162292	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NZ_LR135352	Enterococcus faecium isolate E8014 plasmid 2	144808-144839	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NZ_LR134106	Enterococcus faecium isolate E6043 plasmid 2	74349-74380	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NC_025146	Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111	10348-10379	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NZ_CP011829	Enterococcus faecium strain UW8175 plasmid unnamed1, complete sequence	206389-206420	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NZ_CP045013	Enterococcus faecium strain LAC7.2 plasmid pI, complete sequence	93865-93896	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NC_012654	Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence	105050-105081	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NZ_CP025687	Enterococcus faecium strain CBA7134 plasmid pCBA710401, complete sequence	179991-180022	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NZ_CP040741	Enterococcus faecium strain VRE1 plasmid pVRE1-1, complete sequence	142337-142368	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NZ_CP040877	Enterococcus faecium strain HB-1 plasmid punnamed, complete sequence	119042-119073	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NZ_CP032307	Enterococcus faecium strain HY07 plasmid unnamed2, complete sequence	170141-170172	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NZ_CP031095	Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence	7078-7109	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NZ_CP019993	Enterococcus faecium isolate 2014-VREF-268 plasmid p268-1, complete sequence	191990-192021	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NZ_CP035655	Enterococcus faecium strain UAMSEF_08 plasmid unnamed1, complete sequence	84548-84579	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NZ_CP035137	Enterococcus faecium strain SRCM103341 plasmid unnamed1, complete sequence	50736-50767	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NZ_CP035661	Enterococcus faecium strain UAMSEF_09 plasmid unnamed1, complete sequence	78181-78212	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NZ_CP035667	Enterococcus faecium strain UAMSEF_20 plasmid unnamed1, complete sequence	78183-78214	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NZ_CP035649	Enterococcus faecium strain UAMSEF_01 plasmid unnamed1, complete sequence	84553-84584	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NZ_CP035221	Enterococcus faecium strain SRCM103470 plasmid unnamed1	203456-203487	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	LR135186	Enterococcus faecium isolate E4413 genome assembly, plasmid: 2	85929-85960	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NZ_CP042833	Enterococcus faecium strain FA3 plasmid unnamed1	135451-135482	8	0.75
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NZ_MG674581	Enterococcus faecium strain HL1 plasmid pHLSA, complete sequence	69501-69532	8	0.75
NZ_CP045224_12	12.2\|2802409\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2802409-2802445	37	NC_041928	Staphylococcus phage phiIBB-SEP1, complete genome	37105-37141	8	0.784
NZ_CP045224_12	12.2\|2802409\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2802409-2802445	37	KP027447	Staphylococcus phage phiIPLA-C1C, complete genome	35955-35991	8	0.784
NZ_CP045224_12	12.2\|2802409\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2802409-2802445	37	MH321490	Staphylococcus phage Quidividi, complete genome	71906-71942	8	0.784
NZ_CP045224_12	12.2\|2802409\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2802409-2802445	37	MF417868	Uncultured Caudovirales phage clone 7AX_1, partial genome	110184-110220	8	0.784
NZ_CP045224_13	13.7\|3182659\|30\|NZ_CP045224\|CRISPRCasFinder	3182659-3182688	30	NC_014663	Acinetobacter phage Acj9, complete genome	46685-46714	8	0.733
NZ_CP045224_1	1.3\|337197\|34\|NZ_CP045224\|CRT	337197-337230	34	MT375529	Pelagibacter phage Kolga EXVC01, complete genome	13660-13693	9	0.735
NZ_CP045224_1	1.3\|337197\|34\|NZ_CP045224\|CRT	337197-337230	34	NZ_CP012101	Bacillus thuringiensis strain HS18-1 plasmid pHS18-2, complete sequence	132930-132963	9	0.735
NZ_CP045224_1	1.5\|337293\|34\|NZ_CP045224\|CRT	337293-337326	34	MG945433	UNVERIFIED: Microviridae sp. isolate 4854-1711, complete genome	5255-5288	9	0.735
NZ_CP045224_7	7.38\|1071413\|38\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1071413-1071450	38	MG065657	UNVERIFIED: Campylobacter phage C4, complete genome	13370-13407	9	0.763
NZ_CP045224_7	7.38\|1071413\|38\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1071413-1071450	38	MG065649	UNVERIFIED: Campylobacter phage A143, complete genome	21552-21589	9	0.763
NZ_CP045224_7	7.38\|1071413\|38\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1071413-1071450	38	KC710998	Shigella phage pSf-1, complete genome	51055-51092	9	0.763
NZ_CP045224_7	7.38\|1071413\|38\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1071413-1071450	38	NC_049821	Salmonella phage slyngel, complete genome	28580-28617	9	0.763
NZ_CP045224_7	7.38\|1071413\|38\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1071413-1071450	38	MK373798	Escherichia phage vB_EcoS_G29-2, complete genome	34911-34948	9	0.763
NZ_CP045224_7	7.38\|1071413\|38\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1071413-1071450	38	MG065681	UNVERIFIED: Campylobacter phage A139, complete genome	45515-45552	9	0.763
NZ_CP045224_7	7.38\|1071413\|38\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1071413-1071450	38	MG065680	UNVERIFIED: Campylobacter phage A113, complete genome	22100-22137	9	0.763
NZ_CP045224_7	7.38\|1071413\|38\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1071413-1071450	38	MG065643	UNVERIFIED: Campylobacter phage E6, complete genome	36773-36810	9	0.763
NZ_CP045224_8	8.15\|1794013\|34\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794013-1794046	34	NC_015851	Acidithiobacillus caldus SM-1 megaplasmid, complete sequence	236190-236223	9	0.735
NZ_CP045224_8	8.15\|1794013\|34\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794013-1794046	34	NZ_CP005987	Acidithiobacillus caldus ATCC 51756 plasmid megap mpAca1.1, complete sequence	119031-119064	9	0.735
NZ_CP045224_8	8.15\|1794013\|34\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794013-1794046	34	NZ_CP026329	Acidithiobacillus caldus strain MTH-04 plasmid p1, complete sequence	174745-174778	9	0.735
NZ_CP045224_8	8.35\|1795331\|35\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1795331-1795365	35	MT774406	CrAssphage cr124_1, complete genome	86796-86830	9	0.743
NZ_CP045224_10	10.12\|2319514\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2319514-2319550	37	NZ_LR215006	Mycoplasma conjunctivae strain NCTC10147 plasmid 10	11741-11777	9	0.757
NZ_CP045224_10	10.12\|2319514\|37\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2319514-2319550	37	LR214957	Mycoplasma fermentans strain NCTC10117 genome assembly, plasmid: 3	10204-10240	9	0.757
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NZ_LR214939	Mycoplasma salivarium strain NCTC10113 plasmid 2	379558-379589	9	0.719
NZ_CP045224_11	11.1\|2466602\|32\|NZ_CP045224\|CRISPRCasFinder	2466602-2466633	32	NC_019763	Oscillatoria nigro-viridis PCC 7112 plasmid pOSC7112.01, complete sequence	147487-147518	9	0.719
NZ_CP045224_1	1.3\|337197\|34\|NZ_CP045224\|CRT	337197-337230	34	NZ_CP020744	Bacillus mycoides strain Gnyt1 plasmid unnamed1, complete sequence	49881-49914	10	0.706
NZ_CP045224_1	1.3\|337197\|34\|NZ_CP045224\|CRT	337197-337230	34	NZ_CP020744	Bacillus mycoides strain Gnyt1 plasmid unnamed1, complete sequence	49989-50022	10	0.706
NZ_CP045224_1	1.3\|337197\|34\|NZ_CP045224\|CRT	337197-337230	34	NZ_CP020744	Bacillus mycoides strain Gnyt1 plasmid unnamed1, complete sequence	50025-50058	10	0.706
NZ_CP045224_1	1.5\|337293\|34\|NZ_CP045224\|CRT	337293-337326	34	NZ_CP028489	Yersinia massiliensis strain GTA plasmid unnamed2, complete sequence	28755-28788	10	0.706
NZ_CP045224_1	1.5\|337293\|34\|NZ_CP045224\|CRT	337293-337326	34	MG945309	UNVERIFIED: Microviridae sp. isolate 786-1711, complete genome	5351-5384	10	0.706
NZ_CP045224_1	1.5\|337293\|34\|NZ_CP045224\|CRT	337293-337326	34	NC_009704	Yersinia pseudotuberculosis IP 31758 plasmid p_59kb, complete sequence	12935-12968	10	0.706
NZ_CP045224_2	2.10\|455079\|36\|NZ_CP045224\|CRT	455079-455114	36	MN693862	Marine virus AFVG_250M91, complete genome	4477-4512	10	0.722
NZ_CP045224_2	2.10\|455079\|36\|NZ_CP045224\|CRT	455079-455114	36	MN694690	Marine virus AFVG_250M90, complete genome	19764-19799	10	0.722
NZ_CP045224_2	2.10\|455079\|36\|NZ_CP045224\|CRT	455079-455114	36	MN693992	Marine virus AFVG_250M87, complete genome	8724-8759	10	0.722
NZ_CP045224_2	2.10\|455079\|36\|NZ_CP045224\|CRT	455079-455114	36	KF437907	Phormidium phage MIS-PhV1A, complete genome	8672-8707	10	0.722
NZ_CP045224_2	2.10\|455079\|36\|NZ_CP045224\|CRT	455079-455114	36	KF437907	Phormidium phage MIS-PhV1A, complete genome	8681-8716	10	0.722
NZ_CP045224_2	2.10\|455079\|36\|NZ_CP045224\|CRT	455079-455114	36	MN694247	Marine virus AFVG_250M89, complete genome	17674-17709	10	0.722
NZ_CP045224_2	2.10\|455079\|36\|NZ_CP045224\|CRT	455079-455114	36	MN693850	Marine virus AFVG_250M88, complete genome	20514-20549	10	0.722
NZ_CP045224_3	3.2\|779049\|35\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	779049-779083	35	MN033866	Leviviridae sp. isolate H1_Bulk_Litter_6_scaffold_308 hypothetical protein (H1BulkLitter6308_000001), hypothetical protein (H1BulkLitter6308_000002), RNA-dependent RNA polymerase (H1BulkLitter6308_000003), and hypothetical protein (H1BulkLitter6308_000004) genes, complete cds	3011-3045	10	0.714
NZ_CP045224_7	7.19\|1070163\|35\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	1070163-1070197	35	NZ_CP003988	Streptomyces sp. 769 plasmid pSGZL, complete sequence	80296-80330	10	0.714
NZ_CP045224_8	8.10\|1793685\|35\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1793685-1793719	35	NZ_CP034172	Chryseobacterium taklimakanense strain H4753 plasmid unnamed, complete sequence	21901-21935	10	0.714
NZ_CP045224_8	8.22\|1794474\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794474-1794509	36	NZ_CP050647	Escherichia coli strain PapM-36-2 plasmid pIncFIB, complete sequence	2680-2715	10	0.722
NZ_CP045224_8	8.22\|1794474\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794474-1794509	36	NC_019348	Lactococcus lactis subsp. cremoris plasmid pAF07, complete sequence	2990-3025	10	0.722
NZ_CP045224_8	8.22\|1794474\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794474-1794509	36	MN693542	Marine virus AFVG_25M165, complete genome	18964-18999	10	0.722
NZ_CP045224_8	8.22\|1794474\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794474-1794509	36	MN693056	Marine virus AFVG_25M10, complete genome	18618-18653	11	0.694
NZ_CP045224_8	8.22\|1794474\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794474-1794509	36	MN693152	Marine virus AFVG_25M11, complete genome	41143-41178	11	0.694
NZ_CP045224_8	8.22\|1794474\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794474-1794509	36	MN693342	Marine virus AFVG_25M9, complete genome	18790-18825	11	0.694
NZ_CP045224_8	8.22\|1794474\|36\|NZ_CP045224\|CRT,CRISPRCasFinder,PILER-CR	1794474-1794509	36	MN693020	Marine virus AFVG_117M64, complete genome	41144-41179	11	0.694
NZ_CP045224_10	10.17\|2319843\|36\|NZ_CP045224\|PILER-CR,CRISPRCasFinder,CRT	2319843-2319878	36	NC_014389	Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence	203717-203752	11	0.694
NZ_CP045224_7	7.44\|1071810\|37\|NZ_CP045224\|CRISPRCasFinder,CRT	1071810-1071846	37	HG796590	Uncultured bacterium plasmid pRGI01759	395-431	12	0.676

1. spacer 3.6|779309|34|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029155 (Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

ttgcttatacttacaactttttctgctgtagcat	CRISPR spacer
ttgcttatacttacaactttttctgctgtagcat	Protospacer
**********************************

2. spacer 3.6|779309|34|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to MF547662 (Clostridioides phage LIBA6276, complete genome) position: , mismatch: 0, identity: 1.0

ttgcttatacttacaactttttctgctgtagcat	CRISPR spacer
ttgcttatacttacaactttttctgctgtagcat	Protospacer
**********************************

3. spacer 3.6|779309|34|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to MF547663 (Clostridioides phage LIBA2945, complete genome) position: , mismatch: 0, identity: 1.0

ttgcttatacttacaactttttctgctgtagcat	CRISPR spacer
ttgcttatacttacaactttttctgctgtagcat	Protospacer
**********************************

4. spacer 3.7|779372|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to LN681541 (Clostridium phage phiMMP01, complete genome) position: , mismatch: 0, identity: 1.0

aaaactgtttctacttttttagtcccaagtaattcc	CRISPR spacer
aaaactgtttctacttttttagtcccaagtaattcc	Protospacer
************************************

5. spacer 3.11|779636|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to MK473382 (Clostridium phage JD032, complete genome) position: , mismatch: 0, identity: 1.0

tttgatgaaaaagaagaatataagagggatgtggcaa	CRISPR spacer
tttgatgaaaaagaagaatataagagggatgtggcaa	Protospacer
*************************************

6. spacer 3.12|779702|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_048665 (Clostridium phage phiCDHM14, complete genome) position: , mismatch: 0, identity: 1.0

taactccaaactccgtaagtcttgccatttctccaa	CRISPR spacer
taactccaaactccgtaagtcttgccatttctccaa	Protospacer
************************************

7. spacer 3.12|779702|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to MK473382 (Clostridium phage JD032, complete genome) position: , mismatch: 0, identity: 1.0

taactccaaactccgtaagtcttgccatttctccaa	CRISPR spacer
taactccaaactccgtaagtcttgccatttctccaa	Protospacer
************************************

8. spacer 3.12|779702|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to JX145342 (Clostridium phage phiMMP04, complete genome) position: , mismatch: 0, identity: 1.0

taactccaaactccgtaagtcttgccatttctccaa	CRISPR spacer
taactccaaactccgtaagtcttgccatttctccaa	Protospacer
************************************

9. spacer 3.12|779702|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_028838 (Clostridium phage phiCD506, complete genome) position: , mismatch: 0, identity: 1.0

taactccaaactccgtaagtcttgccatttctccaa	CRISPR spacer
taactccaaactccgtaagtcttgccatttctccaa	Protospacer
************************************

10. spacer 3.12|779702|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to HG796225 (Clostridium phage phiCDHM13 complete genome) position: , mismatch: 0, identity: 1.0

taactccaaactccgtaagtcttgccatttctccaa	CRISPR spacer
taactccaaactccgtaagtcttgccatttctccaa	Protospacer
************************************

11. spacer 3.12|779702|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to LN681538 (Clostridium phage phiCD481-1, complete genome) position: , mismatch: 0, identity: 1.0

taactccaaactccgtaagtcttgccatttctccaa	CRISPR spacer
taactccaaactccgtaagtcttgccatttctccaa	Protospacer
************************************

12. spacer 3.12|779702|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to HG798901 (Clostridium phage phiCDHM11 complete genome) position: , mismatch: 0, identity: 1.0

taactccaaactccgtaagtcttgccatttctccaa	CRISPR spacer
taactccaaactccgtaagtcttgccatttctccaa	Protospacer
************************************

13. spacer 3.13|779767|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_048665 (Clostridium phage phiCDHM14, complete genome) position: , mismatch: 0, identity: 1.0

gagtatcaagagaccagggaaaggcaggtaaagcag	CRISPR spacer
gagtatcaagagaccagggaaaggcaggtaaagcag	Protospacer
************************************

14. spacer 3.13|779767|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to HG796225 (Clostridium phage phiCDHM13 complete genome) position: , mismatch: 0, identity: 1.0

gagtatcaagagaccagggaaaggcaggtaaagcag	CRISPR spacer
gagtatcaagagaccagggaaaggcaggtaaagcag	Protospacer
************************************

15. spacer 3.13|779767|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to HG798901 (Clostridium phage phiCDHM11 complete genome) position: , mismatch: 0, identity: 1.0

gagtatcaagagaccagggaaaggcaggtaaagcag	CRISPR spacer
gagtatcaagagaccagggaaaggcaggtaaagcag	Protospacer
************************************

16. spacer 3.13|779767|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to MK473382 (Clostridium phage JD032, complete genome) position: , mismatch: 0, identity: 1.0

gagtatcaagagaccagggaaaggcaggtaaagcag	CRISPR spacer
gagtatcaagagaccagggaaaggcaggtaaagcag	Protospacer
************************************

17. spacer 3.14|779832|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_048665 (Clostridium phage phiCDHM14, complete genome) position: , mismatch: 0, identity: 1.0

aatggtaaaatgaaggcataataaatttcaatatag	CRISPR spacer
aatggtaaaatgaaggcataataaatttcaatatag	Protospacer
************************************

18. spacer 3.14|779832|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to JX145342 (Clostridium phage phiMMP04, complete genome) position: , mismatch: 0, identity: 1.0

aatggtaaaatgaaggcataataaatttcaatatag	CRISPR spacer
aatggtaaaatgaaggcataataaatttcaatatag	Protospacer
************************************

19. spacer 3.14|779832|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to HG796225 (Clostridium phage phiCDHM13 complete genome) position: , mismatch: 0, identity: 1.0

aatggtaaaatgaaggcataataaatttcaatatag	CRISPR spacer
aatggtaaaatgaaggcataataaatttcaatatag	Protospacer
************************************

20. spacer 3.14|779832|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to LN681538 (Clostridium phage phiCD481-1, complete genome) position: , mismatch: 0, identity: 1.0

aatggtaaaatgaaggcataataaatttcaatatag	CRISPR spacer
aatggtaaaatgaaggcataataaatttcaatatag	Protospacer
************************************

21. spacer 3.14|779832|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to HG798901 (Clostridium phage phiCDHM11 complete genome) position: , mismatch: 0, identity: 1.0

aatggtaaaatgaaggcataataaatttcaatatag	CRISPR spacer
aatggtaaaatgaaggcataataaatttcaatatag	Protospacer
************************************

22. spacer 3.17|780031|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029155 (Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

ttggtagacaacctggtacttggcttaagattgataa	CRISPR spacer
ttggtagacaacctggtacttggcttaagattgataa	Protospacer
*************************************

23. spacer 3.17|780031|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to MF547662 (Clostridioides phage LIBA6276, complete genome) position: , mismatch: 0, identity: 1.0

ttggtagacaacctggtacttggcttaagattgataa	CRISPR spacer
ttggtagacaacctggtacttggcttaagattgataa	Protospacer
*************************************

24. spacer 3.17|780031|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to MF547663 (Clostridioides phage LIBA2945, complete genome) position: , mismatch: 0, identity: 1.0

ttggtagacaacctggtacttggcttaagattgataa	CRISPR spacer
ttggtagacaacctggtacttggcttaagattgataa	Protospacer
*************************************

25. spacer 3.17|780031|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to JX145342 (Clostridium phage phiMMP04, complete genome) position: , mismatch: 0, identity: 1.0

ttggtagacaacctggtacttggcttaagattgataa	CRISPR spacer
ttggtagacaacctggtacttggcttaagattgataa	Protospacer
*************************************

26. spacer 3.29|780813|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_028905 (Clostridium phage phiCD111, complete genome) position: , mismatch: 0, identity: 1.0

taaatatagaataaagcattttagtttacaatgcaa	CRISPR spacer
taaatatagaataaagcattttagtttacaatgcaa	Protospacer
************************************

27. spacer 3.30|780878|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020426 (Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

acctaaaaaatcaatgcagcttatcttatatgcaatg	CRISPR spacer
acctaaaaaatcaatgcagcttatcttatatgcaatg	Protospacer
*************************************

28. spacer 3.30|780878|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to MF547663 (Clostridioides phage LIBA2945, complete genome) position: , mismatch: 0, identity: 1.0

acctaaaaaatcaatgcagcttatcttatatgcaatg	CRISPR spacer
acctaaaaaatcaatgcagcttatcttatatgcaatg	Protospacer
*************************************

29. spacer 3.30|780878|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to CP011970 (Peptoclostridium phage phiCDIF1296T strain DSM 1296, complete sequence) position: , mismatch: 0, identity: 1.0

acctaaaaaatcaatgcagcttatcttatatgcaatg	CRISPR spacer
acctaaaaaatcaatgcagcttatcttatatgcaatg	Protospacer
*************************************

30. spacer 3.30|780878|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to LN681537 (Clostridium phage phiCD211, complete genome) position: , mismatch: 0, identity: 1.0

acctaaaaaatcaatgcagcttatcttatatgcaatg	CRISPR spacer
acctaaaaaatcaatgcagcttatcttatatgcaatg	Protospacer
*************************************

31. spacer 7.2|1069041|35|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to HG531805 (Clostridium phage CDMH1 complete genome) position: , mismatch: 0, identity: 1.0

agggttgagttctggcgtattaagaggtgaggagc	CRISPR spacer
agggttgagttctggcgtattaagaggtgaggagc	Protospacer
***********************************

32. spacer 7.6|1069303|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to LN681539 (Clostridium phage phiCD505, complete genome) position: , mismatch: 0, identity: 1.0

aaataaaagaattaggatttactcaacaatcaattaa	CRISPR spacer
aaataaaagaattaggatttactcaacaatcaattaa	Protospacer
*************************************

33. spacer 7.6|1069303|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to LN681542 (Clostridium phage phiMMP03, complete genome) position: , mismatch: 0, identity: 1.0

aaataaaagaattaggatttactcaacaatcaattaa	CRISPR spacer
aaataaaagaattaggatttactcaacaatcaattaa	Protospacer
*************************************

34. spacer 7.6|1069303|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_009231 (Clostridium phage phiC2, complete genome) position: , mismatch: 0, identity: 1.0

aaataaaagaattaggatttactcaacaatcaattaa	CRISPR spacer
aaataaaagaattaggatttactcaacaatcaattaa	Protospacer
*************************************

35. spacer 7.6|1069303|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_011398 (Clostridium phage phiCD27, complete genome) position: , mismatch: 0, identity: 1.0

aaataaaagaattaggatttactcaacaatcaattaa	CRISPR spacer
aaataaaagaattaggatttactcaacaatcaattaa	Protospacer
*************************************

36. spacer 7.6|1069303|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_048642 (Clostridium phage CDKM9, complete genome) position: , mismatch: 0, identity: 1.0

aaataaaagaattaggatttactcaacaatcaattaa	CRISPR spacer
aaataaaagaattaggatttactcaacaatcaattaa	Protospacer
*************************************

37. spacer 7.10|1069567|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to AY855346 (Clostridium difficile bacteriophage phi CD119, complete genome) position: , mismatch: 0, identity: 1.0

aagaaagacaaacatgttcaaagtcatgttcaaaca	CRISPR spacer
aagaaagacaaacatgttcaaagtcatgttcaaaca	Protospacer
************************************

38. spacer 7.10|1069567|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_007917 (Clostridium phage phi CD119, complete genome) position: , mismatch: 0, identity: 1.0

aagaaagacaaacatgttcaaagtcatgttcaaaca	CRISPR spacer
aagaaagacaaacatgttcaaagtcatgttcaaaca	Protospacer
************************************

39. spacer 7.10|1069567|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_028996 (Clostridium phage phiCDHM19, complete genome) position: , mismatch: 0, identity: 1.0

aagaaagacaaacatgttcaaagtcatgttcaaaca	CRISPR spacer
aagaaagacaaacatgttcaaagtcatgttcaaaca	Protospacer
************************************

40. spacer 7.14|1069830|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020425 (Clostridioides difficile strain FDAARGOS_267 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

tcattataaccccaaccaactacagttgcagggattt	CRISPR spacer
tcattataaccccaaccaactacagttgcagggattt	Protospacer
*************************************

41. spacer 7.14|1069830|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to FN668942 (Clostridium difficile BI1 plasmid pCDBI1, complete sequence) position: , mismatch: 0, identity: 1.0

tcattataaccccaaccaactacagttgcagggattt	CRISPR spacer
tcattataaccccaaccaactacagttgcagggattt	Protospacer
*************************************

42. spacer 7.14|1069830|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP011969 (Clostridioides difficile ATCC 9689 = DSM 1296 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

tcattataaccccaaccaactacagttgcagggattt	CRISPR spacer
tcattataaccccaaccaactacagttgcagggattt	Protospacer
*************************************

43. spacer 7.14|1069830|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to HG531805 (Clostridium phage CDMH1 complete genome) position: , mismatch: 0, identity: 1.0

tcattataaccccaaccaactacagttgcagggattt	CRISPR spacer
tcattataaccccaaccaactacagttgcagggattt	Protospacer
*************************************

44. spacer 7.16|1069964|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_011398 (Clostridium phage phiCD27, complete genome) position: , mismatch: 0, identity: 1.0

aactcttttgctattcgtttcactacattattatcat	CRISPR spacer
aactcttttgctattcgtttcactacattattatcat	Protospacer
*************************************

45. spacer 7.17|1070030|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to LN681542 (Clostridium phage phiMMP03, complete genome) position: , mismatch: 0, identity: 1.0

aaaagtaatgagagtttagaagatagaaggtttagga	CRISPR spacer
aaaagtaatgagagtttagaagatagaaggtttagga	Protospacer
*************************************

46. spacer 7.17|1070030|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_009231 (Clostridium phage phiC2, complete genome) position: , mismatch: 0, identity: 1.0

aaaagtaatgagagtttagaagatagaaggtttagga	CRISPR spacer
aaaagtaatgagagtttagaagatagaaggtttagga	Protospacer
*************************************

47. spacer 7.17|1070030|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to LN681541 (Clostridium phage phiMMP01, complete genome) position: , mismatch: 0, identity: 1.0

aaaagtaatgagagtttagaagatagaaggtttagga	CRISPR spacer
aaaagtaatgagagtttagaagatagaaggtttagga	Protospacer
*************************************

48. spacer 7.20|1070227|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_008226 (Clostridioides difficile 630 plasmid pCD630, complete sequence) position: , mismatch: 0, identity: 1.0

aaaaactaaaacagtctatggctatatgaaaatctc	CRISPR spacer
aaaaactaaaacagtctatggctatatgaaaatctc	Protospacer
************************************

49. spacer 7.20|1070227|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016319 (Clostridioides difficile strain 630 delta erm plasmid pCD630, complete sequence) position: , mismatch: 0, identity: 1.0

aaaaactaaaacagtctatggctatatgaaaatctc	CRISPR spacer
aaaaactaaaacagtctatggctatatgaaaatctc	Protospacer
************************************

50. spacer 7.24|1070491|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_048665 (Clostridium phage phiCDHM14, complete genome) position: , mismatch: 0, identity: 1.0

gtcgtaaaacttaaagatgaaacaaaaggaatgatt	CRISPR spacer
gtcgtaaaacttaaagatgaaacaaaaggaatgatt	Protospacer
************************************

51. spacer 7.24|1070491|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to HG796225 (Clostridium phage phiCDHM13 complete genome) position: , mismatch: 0, identity: 1.0

gtcgtaaaacttaaagatgaaacaaaaggaatgatt	CRISPR spacer
gtcgtaaaacttaaagatgaaacaaaaggaatgatt	Protospacer
************************************

52. spacer 7.24|1070491|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to HG798901 (Clostridium phage phiCDHM11 complete genome) position: , mismatch: 0, identity: 1.0

gtcgtaaaacttaaagatgaaacaaaaggaatgatt	CRISPR spacer
gtcgtaaaacttaaagatgaaacaaaaggaatgatt	Protospacer
************************************

53. spacer 7.24|1070491|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to MK473382 (Clostridium phage JD032, complete genome) position: , mismatch: 0, identity: 1.0

gtcgtaaaacttaaagatgaaacaaaaggaatgatt	CRISPR spacer
gtcgtaaaacttaaagatgaaacaaaaggaatgatt	Protospacer
************************************

54. spacer 7.25|1070556|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to MK473382 (Clostridium phage JD032, complete genome) position: , mismatch: 0, identity: 1.0

agattcgacggagaacttttatctaataaagaaaaac	CRISPR spacer
agattcgacggagaacttttatctaataaagaaaaac	Protospacer
*************************************

55. spacer 7.27|1070688|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_028838 (Clostridium phage phiCD506, complete genome) position: , mismatch: 0, identity: 1.0

tggtttgttgcaacatatgtgttccttcaacatatcc	CRISPR spacer
tggtttgttgcaacatatgtgttccttcaacatatcc	Protospacer
*************************************

56. spacer 7.27|1070688|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to LN681538 (Clostridium phage phiCD481-1, complete genome) position: , mismatch: 0, identity: 1.0

tggtttgttgcaacatatgtgttccttcaacatatcc	CRISPR spacer
tggtttgttgcaacatatgtgttccttcaacatatcc	Protospacer
*************************************

57. spacer 7.28|1070754|38|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029156 (Clostridioides difficile strain CD161 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

gaatctggagcaggtttataagtttctggatagctaga	CRISPR spacer
gaatctggagcaggtttataagtttctggatagctaga	Protospacer
**************************************

58. spacer 7.28|1070754|38|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029153 (Clostridioides difficile strain CDT4 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

gaatctggagcaggtttataagtttctggatagctaga	CRISPR spacer
gaatctggagcaggtttataagtttctggatagctaga	Protospacer
**************************************

59. spacer 7.28|1070754|38|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to MK473382 (Clostridium phage JD032, complete genome) position: , mismatch: 0, identity: 1.0

gaatctggagcaggtttataagtttctggatagctaga	CRISPR spacer
gaatctggagcaggtttataagtttctggatagctaga	Protospacer
**************************************

60. spacer 7.28|1070754|38|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to JX145342 (Clostridium phage phiMMP04, complete genome) position: , mismatch: 0, identity: 1.0

gaatctggagcaggtttataagtttctggatagctaga	CRISPR spacer
gaatctggagcaggtttataagtttctggatagctaga	Protospacer
**************************************

61. spacer 7.29|1070821|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_028838 (Clostridium phage phiCD506, complete genome) position: , mismatch: 0, identity: 1.0

aaaaaatataaaagagctaagcacatgaaggataat	CRISPR spacer
aaaaaatataaaagagctaagcacatgaaggataat	Protospacer
************************************

62. spacer 7.40|1071546|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_048642 (Clostridium phage CDKM9, complete genome) position: , mismatch: 0, identity: 1.0

tcacaaaaacaaggaatacttaagttagcatcaatga	CRISPR spacer
tcacaaaaacaaggaatacttaagttagcatcaatga	Protospacer
*************************************

63. spacer 7.41|1071612|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_048642 (Clostridium phage CDKM9, complete genome) position: , mismatch: 0, identity: 1.0

tcacaaaaacaaggaatacttaagttagcatcaatga	CRISPR spacer
tcacaaaaacaaggaatacttaagttagcatcaatga	Protospacer
*************************************

64. spacer 7.45|1071876|37|NZ_CP045224|CRISPRCasFinder,CRT matches to NZ_MF547664 (Clostridioides difficile strain LIBA-6289 plasmid LIBA6289, complete sequence) position: , mismatch: 0, identity: 1.0

gttgtattacctctgtaattattttttccaaaattac	CRISPR spacer
gttgtattacctctgtaattattttttccaaaattac	Protospacer
*************************************

65. spacer 8.7|1793487|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP029155 (Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

tattaatccttctattggaaaatatcgtcttcaaga	CRISPR spacer
tattaatccttctattggaaaatatcgtcttcaaga	Protospacer
************************************

66. spacer 8.7|1793487|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to MF547662 (Clostridioides phage LIBA6276, complete genome) position: , mismatch: 0, identity: 1.0

tattaatccttctattggaaaatatcgtcttcaaga	CRISPR spacer
tattaatccttctattggaaaatatcgtcttcaaga	Protospacer
************************************

67. spacer 8.7|1793487|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to MF547663 (Clostridioides phage LIBA2945, complete genome) position: , mismatch: 0, identity: 1.0

tattaatccttctattggaaaatatcgtcttcaaga	CRISPR spacer
tattaatccttctattggaaaatatcgtcttcaaga	Protospacer
************************************

68. spacer 8.7|1793487|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to CP011970 (Peptoclostridium phage phiCDIF1296T strain DSM 1296, complete sequence) position: , mismatch: 0, identity: 1.0

tattaatccttctattggaaaatatcgtcttcaaga	CRISPR spacer
tattaatccttctattggaaaatatcgtcttcaaga	Protospacer
************************************

69. spacer 8.7|1793487|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to LN681537 (Clostridium phage phiCD211, complete genome) position: , mismatch: 0, identity: 1.0

tattaatccttctattggaaaatatcgtcttcaaga	CRISPR spacer
tattaatccttctattggaaaatatcgtcttcaaga	Protospacer
************************************

70. spacer 8.7|1793487|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP020426 (Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

tattaatccttctattggaaaatatcgtcttcaaga	CRISPR spacer
tattaatccttctattggaaaatatcgtcttcaaga	Protospacer
************************************

71. spacer 8.11|1793750|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP020426 (Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

ttttgaagtttagttatatctgggtcaccagtctgt	CRISPR spacer
ttttgaagtttagttatatctgggtcaccagtctgt	Protospacer
************************************

72. spacer 8.11|1793750|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP029155 (Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

ttttgaagtttagttatatctgggtcaccagtctgt	CRISPR spacer
ttttgaagtttagttatatctgggtcaccagtctgt	Protospacer
************************************

73. spacer 8.11|1793750|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to CP011970 (Peptoclostridium phage phiCDIF1296T strain DSM 1296, complete sequence) position: , mismatch: 0, identity: 1.0

ttttgaagtttagttatatctgggtcaccagtctgt	CRISPR spacer
ttttgaagtttagttatatctgggtcaccagtctgt	Protospacer
************************************

74. spacer 8.11|1793750|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to LN681537 (Clostridium phage phiCD211, complete genome) position: , mismatch: 0, identity: 1.0

ttttgaagtttagttatatctgggtcaccagtctgt	CRISPR spacer
ttttgaagtttagttatatctgggtcaccagtctgt	Protospacer
************************************

75. spacer 8.17|1794143|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP020426 (Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

ggattatccaatctttaatcttattaccataccatt	CRISPR spacer
ggattatccaatctttaatcttattaccataccatt	Protospacer
************************************

76. spacer 8.17|1794143|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to CP011970 (Peptoclostridium phage phiCDIF1296T strain DSM 1296, complete sequence) position: , mismatch: 0, identity: 1.0

ggattatccaatctttaatcttattaccataccatt	CRISPR spacer
ggattatccaatctttaatcttattaccataccatt	Protospacer
************************************

77. spacer 8.17|1794143|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to LN681537 (Clostridium phage phiCD211, complete genome) position: , mismatch: 0, identity: 1.0

ggattatccaatctttaatcttattaccataccatt	CRISPR spacer
ggattatccaatctttaatcttattaccataccatt	Protospacer
************************************

78. spacer 8.18|1794209|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP020426 (Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

tatctcttaaagcactatctaattcaacaatagttg	CRISPR spacer
tatctcttaaagcactatctaattcaacaatagttg	Protospacer
************************************

79. spacer 8.18|1794209|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP029155 (Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

tatctcttaaagcactatctaattcaacaatagttg	CRISPR spacer
tatctcttaaagcactatctaattcaacaatagttg	Protospacer
************************************

80. spacer 8.18|1794209|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to CP011970 (Peptoclostridium phage phiCDIF1296T strain DSM 1296, complete sequence) position: , mismatch: 0, identity: 1.0

tatctcttaaagcactatctaattcaacaatagttg	CRISPR spacer
tatctcttaaagcactatctaattcaacaatagttg	Protospacer
************************************

81. spacer 8.18|1794209|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to LN681537 (Clostridium phage phiCD211, complete genome) position: , mismatch: 0, identity: 1.0

tatctcttaaagcactatctaattcaacaatagttg	CRISPR spacer
tatctcttaaagcactatctaattcaacaatagttg	Protospacer
************************************

82. spacer 8.19|1794275|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP029155 (Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

tattgaacttagcatctaatttagtatttttagtag	CRISPR spacer
tattgaacttagcatctaatttagtatttttagtag	Protospacer
************************************

83. spacer 8.32|1795134|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to KU057941 (Clostridium phage CDSH1, complete genome) position: , mismatch: 0, identity: 1.0

tcaaagatgcccctctagctggtttttgggtatcta	CRISPR spacer
tcaaagatgcccctctagctggtttttgggtatcta	Protospacer
************************************

84. spacer 8.32|1795134|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to NC_028905 (Clostridium phage phiCD111, complete genome) position: , mismatch: 0, identity: 1.0

tcaaagatgcccctctagctggtttttgggtatcta	CRISPR spacer
tcaaagatgcccctctagctggtttttgggtatcta	Protospacer
************************************

85. spacer 8.32|1795134|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to HM568888 (Clostridium phage phiCD38-2, complete genome) position: , mismatch: 0, identity: 1.0

tcaaagatgcccctctagctggtttttgggtatcta	CRISPR spacer
tcaaagatgcccctctagctggtttttgggtatcta	Protospacer
************************************

86. spacer 8.32|1795134|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to NC_028958 (Clostridium phage phiCD146, complete genome) position: , mismatch: 0, identity: 1.0

tcaaagatgcccctctagctggtttttgggtatcta	CRISPR spacer
tcaaagatgcccctctagctggtttttgggtatcta	Protospacer
************************************

87. spacer 8.32|1795134|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to LN881738 (Escherichia phage slur17, complete genome) position: , mismatch: 0, identity: 1.0

tcaaagatgcccctctagctggtttttgggtatcta	CRISPR spacer
tcaaagatgcccctctagctggtttttgggtatcta	Protospacer
************************************

88. spacer 8.38|1795528|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to AY855346 (Clostridium difficile bacteriophage phi CD119, complete genome) position: , mismatch: 0, identity: 1.0

gctaacttaattacttgttccacatttgctaatacc	CRISPR spacer
gctaacttaattacttgttccacatttgctaatacc	Protospacer
************************************

89. spacer 8.38|1795528|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to NC_007917 (Clostridium phage phi CD119, complete genome) position: , mismatch: 0, identity: 1.0

gctaacttaattacttgttccacatttgctaatacc	CRISPR spacer
gctaacttaattacttgttccacatttgctaatacc	Protospacer
************************************

90. spacer 8.38|1795528|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to HG531805 (Clostridium phage CDMH1 complete genome) position: , mismatch: 0, identity: 1.0

gctaacttaattacttgttccacatttgctaatacc	CRISPR spacer
gctaacttaattacttgttccacatttgctaatacc	Protospacer
************************************

91. spacer 9.7|1906247|37|NZ_CP045224|PILER-CR matches to NZ_CP020425 (Clostridioides difficile strain FDAARGOS_267 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

tttaatagcacatcttcgctttcaagtttctctatca	CRISPR spacer
tttaatagcacatcttcgctttcaagtttctctatca	Protospacer
*************************************

92. spacer 9.7|1906247|37|NZ_CP045224|PILER-CR matches to FN668942 (Clostridium difficile BI1 plasmid pCDBI1, complete sequence) position: , mismatch: 0, identity: 1.0

tttaatagcacatcttcgctttcaagtttctctatca	CRISPR spacer
tttaatagcacatcttcgctttcaagtttctctatca	Protospacer
*************************************

93. spacer 9.7|1906247|37|NZ_CP045224|PILER-CR matches to NZ_CP011969 (Clostridioides difficile ATCC 9689 = DSM 1296 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

tttaatagcacatcttcgctttcaagtttctctatca	CRISPR spacer
tttaatagcacatcttcgctttcaagtttctctatca	Protospacer
*************************************

94. spacer 9.19|1906248|36|NZ_CP045224|CRISPRCasFinder,CRT matches to NZ_CP020425 (Clostridioides difficile strain FDAARGOS_267 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

ttaatagcacatcttcgctttcaagtttctctatca	CRISPR spacer
ttaatagcacatcttcgctttcaagtttctctatca	Protospacer
************************************

95. spacer 9.19|1906248|36|NZ_CP045224|CRISPRCasFinder,CRT matches to FN668942 (Clostridium difficile BI1 plasmid pCDBI1, complete sequence) position: , mismatch: 0, identity: 1.0

ttaatagcacatcttcgctttcaagtttctctatca	CRISPR spacer
ttaatagcacatcttcgctttcaagtttctctatca	Protospacer
************************************

96. spacer 9.19|1906248|36|NZ_CP045224|CRISPRCasFinder,CRT matches to NZ_CP011969 (Clostridioides difficile ATCC 9689 = DSM 1296 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

ttaatagcacatcttcgctttcaagtttctctatca	CRISPR spacer
ttaatagcacatcttcgctttcaagtttctctatca	Protospacer
************************************

97. spacer 10.11|2319449|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to GU949551 (Clostridium phage phiCD6356, complete genome) position: , mismatch: 0, identity: 1.0

cgcccttttcgctattattttttttataacccttca	CRISPR spacer
cgcccttttcgctattattttttttataacccttca	Protospacer
************************************

98. spacer 10.15|2319711|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to AY855346 (Clostridium difficile bacteriophage phi CD119, complete genome) position: , mismatch: 0, identity: 1.0

caggacaaaatagattatttgactggttaagaaataa	CRISPR spacer
caggacaaaatagattatttgactggttaagaaataa	Protospacer
*************************************

99. spacer 10.15|2319711|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_007917 (Clostridium phage phi CD119, complete genome) position: , mismatch: 0, identity: 1.0

caggacaaaatagattatttgactggttaagaaataa	CRISPR spacer
caggacaaaatagattatttgactggttaagaaataa	Protospacer
*************************************

100. spacer 10.15|2319711|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to LN681542 (Clostridium phage phiMMP03, complete genome) position: , mismatch: 0, identity: 1.0

caggacaaaatagattatttgactggttaagaaataa	CRISPR spacer
caggacaaaatagattatttgactggttaagaaataa	Protospacer
*************************************

101. spacer 10.15|2319711|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_009231 (Clostridium phage phiC2, complete genome) position: , mismatch: 0, identity: 1.0

caggacaaaatagattatttgactggttaagaaataa	CRISPR spacer
caggacaaaatagattatttgactggttaagaaataa	Protospacer
*************************************

102. spacer 10.15|2319711|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to JX145341 (Clostridium phage phiMMP02, complete genome) position: , mismatch: 0, identity: 1.0

caggacaaaatagattatttgactggttaagaaataa	CRISPR spacer
caggacaaaatagattatttgactggttaagaaataa	Protospacer
*************************************

103. spacer 10.15|2319711|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to LN681541 (Clostridium phage phiMMP01, complete genome) position: , mismatch: 0, identity: 1.0

caggacaaaatagattatttgactggttaagaaataa	CRISPR spacer
caggacaaaatagattatttgactggttaagaaataa	Protospacer
*************************************

104. spacer 10.15|2319711|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_011398 (Clostridium phage phiCD27, complete genome) position: , mismatch: 0, identity: 1.0

caggacaaaatagattatttgactggttaagaaataa	CRISPR spacer
caggacaaaatagattatttgactggttaagaaataa	Protospacer
*************************************

105. spacer 10.15|2319711|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_048642 (Clostridium phage CDKM9, complete genome) position: , mismatch: 0, identity: 1.0

caggacaaaatagattatttgactggttaagaaataa	CRISPR spacer
caggacaaaatagattatttgactggttaagaaataa	Protospacer
*************************************

106. spacer 12.7|2802740|38|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_008226 (Clostridioides difficile 630 plasmid pCD630, complete sequence) position: , mismatch: 0, identity: 1.0

gtcttttcaatctgttcaactaccttaggttcattcag	CRISPR spacer
gtcttttcaatctgttcaactaccttaggttcattcag	Protospacer
**************************************

107. spacer 12.7|2802740|38|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016319 (Clostridioides difficile strain 630 delta erm plasmid pCD630, complete sequence) position: , mismatch: 0, identity: 1.0

gtcttttcaatctgttcaactaccttaggttcattcag	CRISPR spacer
gtcttttcaatctgttcaactaccttaggttcattcag	Protospacer
**************************************

108. spacer 12.8|2802807|38|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MG266000 (Clostridioides difficile strain 7032985 plasmid pCD-ISS1, complete sequence) position: , mismatch: 0, identity: 1.0

cttatacttccgttattaaacatcatatctgctattat	CRISPR spacer
cttatacttccgttattaaacatcatatctgctattat	Protospacer
**************************************

109. spacer 14.1|3936194|28|NZ_CP045224|CRISPRCasFinder matches to NZ_CP033215 (Clostridioides difficile strain 12038 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

gttgattcatattgctttaacttattac	CRISPR spacer
gttgattcatattgctttaacttattac	Protospacer
****************************

110. spacer 1.7|337392|22|NZ_CP045224|CRT matches to MK213796 (Escherichia phage T1, complete genome) position: , mismatch: 1, identity: 0.955

tgcaactggagcaacaggattt	CRISPR spacer
tgcaactgtagcaacaggattt	Protospacer
******** *************

111. spacer 1.7|337392|22|NZ_CP045224|CRT matches to NC_047785 (Shigella phage SH6, complete genome) position: , mismatch: 1, identity: 0.955

tgcaactggagcaacaggattt	CRISPR spacer
tgcaactgtagcaacaggattt	Protospacer
******** *************

112. spacer 1.7|337392|22|NZ_CP045224|CRT matches to MN153797 (Escherichia virus T1 isolate 22, complete genome) position: , mismatch: 1, identity: 0.955

tgcaactggagcaacaggattt	CRISPR spacer
tgcaactgtagcaacaggattt	Protospacer
******** *************

113. spacer 1.7|337392|22|NZ_CP045224|CRT matches to KU194206 (Escherichia phage JMPW1, complete genome) position: , mismatch: 1, identity: 0.955

tgcaactggagcaacaggattt	CRISPR spacer
tgcaactgtagcaacaggattt	Protospacer
******** *************

114. spacer 1.7|337392|22|NZ_CP045224|CRT matches to NC_041873 (Escherichia phage JMPW2, complete genome) position: , mismatch: 1, identity: 0.955

tgcaactggagcaacaggattt	CRISPR spacer
tgcaactgtagcaacaggattt	Protospacer
******** *************

115. spacer 1.7|337392|22|NZ_CP045224|CRT matches to JX912252 (Escherichia phage ADB-2, complete genome) position: , mismatch: 1, identity: 0.955

tgcaactggagcaacaggattt	CRISPR spacer
tgcaactgtagcaacaggattt	Protospacer
******** *************

116. spacer 1.7|337392|22|NZ_CP045224|CRT matches to NC_049831 (Shigella virus Sfin-3, complete genome) position: , mismatch: 1, identity: 0.955

tgcaactggagcaacaggattt	CRISPR spacer
tgcaactgtagcaacaggattt	Protospacer
******** *************

117. spacer 1.7|337392|22|NZ_CP045224|CRT matches to HM035024 (Shigella phage Shfl1, complete genome) position: , mismatch: 1, identity: 0.955

tgcaactggagcaacaggattt	CRISPR spacer
tgcaactgtagcaacaggattt	Protospacer
******** *************

118. spacer 1.7|337392|22|NZ_CP045224|CRT matches to MH917278 (Shigella phage phi2457T, complete genome) position: , mismatch: 1, identity: 0.955

tgcaactggagcaacaggattt	CRISPR spacer
tgcaactgtagcaacaggattt	Protospacer
******** *************

119. spacer 1.7|337392|22|NZ_CP045224|CRT matches to MT682715 (Escherichia phage vB_EcoS_Chapo, complete genome) position: , mismatch: 1, identity: 0.955

tgcaactggagcaacaggattt	CRISPR spacer
tgcaactgtagcaacaggattt	Protospacer
******** *************

120. spacer 1.7|337392|22|NZ_CP045224|CRT matches to KY985004 (Escherichia phage vB_EcoS_SH2, complete genome) position: , mismatch: 1, identity: 0.955

tgcaactggagcaacaggattt	CRISPR spacer
tgcaactgtagcaacaggattt	Protospacer
******** *************

121. spacer 1.7|337392|22|NZ_CP045224|CRT matches to NC_005833 (Enterobacteria phage T1, complete genome) position: , mismatch: 1, identity: 0.955

tgcaactggagcaacaggattt	CRISPR spacer
tgcaactgtagcaacaggattt	Protospacer
******** *************

122. spacer 1.7|337392|22|NZ_CP045224|CRT matches to KP085586 (Shigella phage pSf-2, complete genome) position: , mismatch: 1, identity: 0.955

tgcaactggagcaacaggattt	CRISPR spacer
tgcaactgtagcaacaggattt	Protospacer
******** *************

123. spacer 1.7|337392|22|NZ_CP045224|CRT matches to MH051912 (Enterobacteria phage vB_EcoS_IME167, complete genome) position: , mismatch: 1, identity: 0.955

tgcaactggagcaacaggattt	CRISPR spacer
tgcaactgtagcaacaggattt	Protospacer
******** *************

124. spacer 1.7|337392|22|NZ_CP045224|CRT matches to NC_049832 (Escherichia phage vB_EcoS-DELF2 DNA, complete genome) position: , mismatch: 1, identity: 0.955

tgcaactggagcaacaggattt	CRISPR spacer
tgcaactgtagcaacaggattt	Protospacer
******** *************

125. spacer 1.7|337392|22|NZ_CP045224|CRT matches to NC_041995 (Shigella phage vB_SsoS-ISF002, complete genome) position: , mismatch: 1, identity: 0.955

tgcaactggagcaacaggattt	CRISPR spacer
tgcaactgtagcaacaggattt	Protospacer
******** *************

126. spacer 3.2|779049|35|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_048642 (Clostridium phage CDKM9, complete genome) position: , mismatch: 1, identity: 0.971

attctttatacagagaaacacgatactatttacag	CRISPR spacer
attctttatacagagaaacacgatactatttatag	Protospacer
********************************.**

127. spacer 3.4|779178|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to LN681542 (Clostridium phage phiMMP03, complete genome) position: , mismatch: 1, identity: 0.972

aattgcataatattagagagtttaataccatcaagt	CRISPR spacer
aattgtataatattagagagtttaataccatcaagt	Protospacer
*****.******************************

128. spacer 3.4|779178|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to HG531805 (Clostridium phage CDMH1 complete genome) position: , mismatch: 1, identity: 0.972

aattgcataatattagagagtttaataccatcaagt	CRISPR spacer
aattgtataatattagagagtttaataccatcaagt	Protospacer
*****.******************************

129. spacer 3.4|779178|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_009231 (Clostridium phage phiC2, complete genome) position: , mismatch: 1, identity: 0.972

aattgcataatattagagagtttaataccatcaagt	CRISPR spacer
aattgtataatattagagagtttaataccatcaagt	Protospacer
*****.******************************

130. spacer 3.4|779178|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to LN681541 (Clostridium phage phiMMP01, complete genome) position: , mismatch: 1, identity: 0.972

aattgcataatattagagagtttaataccatcaagt	CRISPR spacer
aattgtataatattagagagtttaataccatcaagt	Protospacer
*****.******************************

131. spacer 3.7|779372|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to AY855346 (Clostridium difficile bacteriophage phi CD119, complete genome) position: , mismatch: 1, identity: 0.972

aaaactgtttctacttttttagtcccaagtaattcc	CRISPR spacer
aaaattgtttctacttttttagtcccaagtaattcc	Protospacer
****.*******************************

132. spacer 3.7|779372|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_007917 (Clostridium phage phi CD119, complete genome) position: , mismatch: 1, identity: 0.972

aaaactgtttctacttttttagtcccaagtaattcc	CRISPR spacer
aaaattgtttctacttttttagtcccaagtaattcc	Protospacer
****.*******************************

133. spacer 3.7|779372|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to LN681539 (Clostridium phage phiCD505, complete genome) position: , mismatch: 1, identity: 0.972

aaaactgtttctacttttttagtcccaagtaattcc	CRISPR spacer
aaaactgtttctacttttttagtaccaagtaattcc	Protospacer
*********************** ************

134. spacer 3.7|779372|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to LN681542 (Clostridium phage phiMMP03, complete genome) position: , mismatch: 1, identity: 0.972

aaaactgtttctacttttttagtcccaagtaattcc	CRISPR spacer
aaaactgtttctacttttttagtaccaagtaattcc	Protospacer
*********************** ************

135. spacer 3.7|779372|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to HG531805 (Clostridium phage CDMH1 complete genome) position: , mismatch: 1, identity: 0.972

aaaactgtttctacttttttagtcccaagtaattcc	CRISPR spacer
aaaactgtttctacttttttagtaccaagtaattcc	Protospacer
*********************** ************

136. spacer 3.7|779372|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_009231 (Clostridium phage phiC2, complete genome) position: , mismatch: 1, identity: 0.972

aaaactgtttctacttttttagtcccaagtaattcc	CRISPR spacer
aaaactgtttctacttttttagtaccaagtaattcc	Protospacer
*********************** ************

137. spacer 3.7|779372|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to KX228400 (Clostridium phage CDKM15, complete genome) position: , mismatch: 1, identity: 0.972

aaaactgtttctacttttttagtcccaagtaattcc	CRISPR spacer
aaaactgtttctacttttttagtaccaagtaattcc	Protospacer
*********************** ************

138. spacer 3.9|779503|38|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_028996 (Clostridium phage phiCDHM19, complete genome) position: , mismatch: 1, identity: 0.974

tctaaaatatcctcacaactcctgtaattgtattttct	CRISPR spacer
tctaaaatatcctcacaactcctgtaattgtattttcc	Protospacer
*************************************.

139. spacer 3.11|779636|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_008226 (Clostridioides difficile 630 plasmid pCD630, complete sequence) position: , mismatch: 1, identity: 0.973

tttgatgaaaaagaagaatataagagggatgtggcaa	CRISPR spacer
tttgatgaaaaagaagagtataagagggatgtggcaa	Protospacer
*****************.*******************

140. spacer 3.11|779636|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016319 (Clostridioides difficile strain 630 delta erm plasmid pCD630, complete sequence) position: , mismatch: 1, identity: 0.973

tttgatgaaaaagaagaatataagagggatgtggcaa	CRISPR spacer
tttgatgaaaaagaagagtataagagggatgtggcaa	Protospacer
*****************.*******************

141. spacer 3.11|779636|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_048665 (Clostridium phage phiCDHM14, complete genome) position: , mismatch: 1, identity: 0.973

tttgatgaaaaagaagaatataagagggatgtggcaa	CRISPR spacer
tttgatgaaaaagaagagtataagagggatgtggcaa	Protospacer
*****************.*******************

142. spacer 3.11|779636|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_028838 (Clostridium phage phiCD506, complete genome) position: , mismatch: 1, identity: 0.973

tttgatgaaaaagaagaatataagagggatgtggcaa	CRISPR spacer
tttgatgaaaaagaagagtataagagggatgtggcaa	Protospacer
*****************.*******************

143. spacer 3.11|779636|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to HG796225 (Clostridium phage phiCDHM13 complete genome) position: , mismatch: 1, identity: 0.973

tttgatgaaaaagaagaatataagagggatgtggcaa	CRISPR spacer
tttgatgaaaaagaagagtataagagggatgtggcaa	Protospacer
*****************.*******************

144. spacer 3.11|779636|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to LN681538 (Clostridium phage phiCD481-1, complete genome) position: , mismatch: 1, identity: 0.973

tttgatgaaaaagaagaatataagagggatgtggcaa	CRISPR spacer
tttgatgaaaaagaagagtataagagggatgtggcaa	Protospacer
*****************.*******************

145. spacer 3.22|780356|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to JX145342 (Clostridium phage phiMMP04, complete genome) position: , mismatch: 1, identity: 0.972

attgtaagctctttaatttctaaattagctccgatt	CRISPR spacer
attgtaagctctttgatttctaaattagctccgatt	Protospacer
**************.*********************

146. spacer 3.26|780616|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029156 (Clostridioides difficile strain CD161 plasmid unnamed2, complete sequence) position: , mismatch: 1, identity: 0.973

ttatgttataggagcaggttgcaagaagtataagcaa	CRISPR spacer
ttatgttataggagcaggttgcaagaaatataagcaa	Protospacer
***************************.*********

147. spacer 3.26|780616|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029153 (Clostridioides difficile strain CDT4 plasmid unnamed1, complete sequence) position: , mismatch: 1, identity: 0.973

ttatgttataggagcaggttgcaagaagtataagcaa	CRISPR spacer
ttatgttataggagcaggttgcaagaaatataagcaa	Protospacer
***************************.*********

148. spacer 3.26|780616|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_048665 (Clostridium phage phiCDHM14, complete genome) position: , mismatch: 1, identity: 0.973

ttatgttataggagcaggttgcaagaagtataagcaa	CRISPR spacer
ttatgttataggagcaggttgcaagaaatataagcaa	Protospacer
***************************.*********

149. spacer 3.26|780616|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to HG796225 (Clostridium phage phiCDHM13 complete genome) position: , mismatch: 1, identity: 0.973

ttatgttataggagcaggttgcaagaagtataagcaa	CRISPR spacer
ttatgttataggagcaggttgcaagaaatataagcaa	Protospacer
***************************.*********

150. spacer 3.26|780616|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to HG798901 (Clostridium phage phiCDHM11 complete genome) position: , mismatch: 1, identity: 0.973

ttatgttataggagcaggttgcaagaagtataagcaa	CRISPR spacer
ttatgttataggagcaggttgcaagaaatataagcaa	Protospacer
***************************.*********

151. spacer 3.30|780878|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029155 (Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence) position: , mismatch: 1, identity: 0.973

acctaaaaaatcaatgcagcttatcttatatgcaatg	CRISPR spacer
acctaaaaaatcaatgcaacttatcttatatgcaatg	Protospacer
******************.******************

152. spacer 7.2|1069041|35|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to LN681542 (Clostridium phage phiMMP03, complete genome) position: , mismatch: 1, identity: 0.971

agggttgagttctggcgtattaagaggtgaggagc	CRISPR spacer
agggttgagttctggcgtattaagaggtgaggaac	Protospacer
*********************************.*

153. spacer 7.2|1069041|35|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_009231 (Clostridium phage phiC2, complete genome) position: , mismatch: 1, identity: 0.971

agggttgagttctggcgtattaagaggtgaggagc	CRISPR spacer
agggttgagttctggcgtattaagaggtgaggaac	Protospacer
*********************************.*

154. spacer 7.2|1069041|35|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to LN681541 (Clostridium phage phiMMP01, complete genome) position: , mismatch: 1, identity: 0.971

agggttgagttctggcgtattaagaggtgaggagc	CRISPR spacer
agggttgagttctggcgtattaagaggtgaggaac	Protospacer
*********************************.*

155. spacer 7.4|1069171|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to LN681539 (Clostridium phage phiCD505, complete genome) position: , mismatch: 1, identity: 0.972

agtgaaagcaaggctattcctaattcttggagtgga	CRISPR spacer
agtgaaagcaaggctattcctaattcttggagttga	Protospacer
********************************* **

156. spacer 7.4|1069171|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to LN681542 (Clostridium phage phiMMP03, complete genome) position: , mismatch: 1, identity: 0.972

agtgaaagcaaggctattcctaattcttggagtgga	CRISPR spacer
agtgaaagcaaggctattcctaattctcggagtgga	Protospacer
***************************.********

157. spacer 7.4|1069171|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_009231 (Clostridium phage phiC2, complete genome) position: , mismatch: 1, identity: 0.972

agtgaaagcaaggctattcctaattcttggagtgga	CRISPR spacer
agtgaaagcaaggctattcctaattctcggagtgga	Protospacer
***************************.********

158. spacer 7.4|1069171|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_048642 (Clostridium phage CDKM9, complete genome) position: , mismatch: 1, identity: 0.972

agtgaaagcaaggctattcctaattcttggagtgga	CRISPR spacer
agtgaaagcaaggctattcctaattctcggagtgga	Protospacer
***************************.********

159. spacer 7.5|1069236|38|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to LN681542 (Clostridium phage phiMMP03, complete genome) position: , mismatch: 1, identity: 0.974

aaataagttttgaagcagaatttacacacaataaacta	CRISPR spacer
aaataagttttgaagcagaatttacacataataaacta	Protospacer
****************************.*********

160. spacer 7.5|1069236|38|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_009231 (Clostridium phage phiC2, complete genome) position: , mismatch: 1, identity: 0.974

aaataagttttgaagcagaatttacacacaataaacta	CRISPR spacer
aaataagttttgaagcagaatttacacataataaacta	Protospacer
****************************.*********

161. spacer 7.5|1069236|38|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to LN681541 (Clostridium phage phiMMP01, complete genome) position: , mismatch: 1, identity: 0.974

aaataagttttgaagcagaatttacacacaataaacta	CRISPR spacer
aaataagttttgaagcagaatttacacataataaacta	Protospacer
****************************.*********

162. spacer 7.14|1069830|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_048665 (Clostridium phage phiCDHM14, complete genome) position: , mismatch: 1, identity: 0.973

tcattataaccccaaccaactacagttgcagggattt	CRISPR spacer
tcattatacccccaaccaactacagttgcagggattt	Protospacer
******** ****************************

163. spacer 7.14|1069830|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to LN681539 (Clostridium phage phiCD505, complete genome) position: , mismatch: 1, identity: 0.973

tcattataaccccaaccaactacagttgcagggattt	CRISPR spacer
tcattataaccccagccaactacagttgcagggattt	Protospacer
**************.**********************

164. spacer 7.14|1069830|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to JX145342 (Clostridium phage phiMMP04, complete genome) position: , mismatch: 1, identity: 0.973

tcattataaccccaaccaactacagttgcagggattt	CRISPR spacer
tcattatagccccaaccaactacagttgcagggattt	Protospacer
********.****************************

165. spacer 7.14|1069830|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to LN681542 (Clostridium phage phiMMP03, complete genome) position: , mismatch: 1, identity: 0.973

tcattataaccccaaccaactacagttgcagggattt	CRISPR spacer
tcattataaccccagccaactacagttgcagggattt	Protospacer
**************.**********************

166. spacer 7.14|1069830|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_028838 (Clostridium phage phiCD506, complete genome) position: , mismatch: 1, identity: 0.973

tcattataaccccaaccaactacagttgcagggattt	CRISPR spacer
tcattataaccccaaccaaccacagttgcagggattt	Protospacer
********************.****************

167. spacer 7.14|1069830|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to HG796225 (Clostridium phage phiCDHM13 complete genome) position: , mismatch: 1, identity: 0.973

tcattataaccccaaccaactacagttgcagggattt	CRISPR spacer
tcattatacccccaaccaactacagttgcagggattt	Protospacer
******** ****************************

168. spacer 7.14|1069830|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to JX145341 (Clostridium phage phiMMP02, complete genome) position: , mismatch: 1, identity: 0.973

tcattataaccccaaccaactacagttgcagggattt	CRISPR spacer
tcattataaccccagccaactacagttgcagggattt	Protospacer
**************.**********************

169. spacer 7.14|1069830|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to LN681541 (Clostridium phage phiMMP01, complete genome) position: , mismatch: 1, identity: 0.973

tcattataaccccaaccaactacagttgcagggattt	CRISPR spacer
tcattatagccccaaccaactacagttgcagggattt	Protospacer
********.****************************

170. spacer 7.14|1069830|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_011398 (Clostridium phage phiCD27, complete genome) position: , mismatch: 1, identity: 0.973

tcattataaccccaaccaactacagttgcagggattt	CRISPR spacer
tcattataaccccaaccaactacagttgcagagattt	Protospacer
*******************************.*****

171. spacer 7.14|1069830|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to HG798901 (Clostridium phage phiCDHM11 complete genome) position: , mismatch: 1, identity: 0.973

tcattataaccccaaccaactacagttgcagggattt	CRISPR spacer
tcattatacccccaaccaactacagttgcagggattt	Protospacer
******** ****************************

172. spacer 7.14|1069830|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to KX228400 (Clostridium phage CDKM15, complete genome) position: , mismatch: 1, identity: 0.973

tcattataaccccaaccaactacagttgcagggattt	CRISPR spacer
tcattataaccccagccaactacagttgcagggattt	Protospacer
**************.**********************

173. spacer 7.22|1070358|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to LN681539 (Clostridium phage phiCD505, complete genome) position: , mismatch: 1, identity: 0.973

tctattccaacataaagatacaaagtagtttcttttt	CRISPR spacer
tctattccaacataaagatataaagtagtttcttttt	Protospacer
********************.****************

174. spacer 7.22|1070358|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to LN681542 (Clostridium phage phiMMP03, complete genome) position: , mismatch: 1, identity: 0.973

tctattccaacataaagatacaaagtagtttcttttt	CRISPR spacer
tctattccaacataaagatataaagtagtttcttttt	Protospacer
********************.****************

175. spacer 7.28|1070754|38|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020425 (Clostridioides difficile strain FDAARGOS_267 plasmid unnamed1, complete sequence) position: , mismatch: 1, identity: 0.974

gaatctggagcaggtttataagtttctggatagctaga	CRISPR spacer
gaatctggagcaggtttataagtttcgggatagctaga	Protospacer
************************** ***********

176. spacer 7.28|1070754|38|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to FN668942 (Clostridium difficile BI1 plasmid pCDBI1, complete sequence) position: , mismatch: 1, identity: 0.974

gaatctggagcaggtttataagtttctggatagctaga	CRISPR spacer
gaatctggagcaggtttataagtttcgggatagctaga	Protospacer
************************** ***********

177. spacer 7.28|1070754|38|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP011969 (Clostridioides difficile ATCC 9689 = DSM 1296 plasmid unnamed, complete sequence) position: , mismatch: 1, identity: 0.974

gaatctggagcaggtttataagtttctggatagctaga	CRISPR spacer
gaatctggagcaggtttataagtttcgggatagctaga	Protospacer
************************** ***********

178. spacer 7.29|1070821|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to LN681538 (Clostridium phage phiCD481-1, complete genome) position: , mismatch: 1, identity: 0.972

aaaaaatataaaagagctaagcacatgaaggataat	CRISPR spacer
aaaaaatataaaagagctaagcacatgaaagataat	Protospacer
*****************************.******

179. spacer 7.32|1071018|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_009231 (Clostridium phage phiC2, complete genome) position: , mismatch: 1, identity: 0.973

ggaagtataatttttactttatctccatactcaaaaa	CRISPR spacer
ggaagtataatttttactttatctccatattcaaaaa	Protospacer
*****************************.*******

180. spacer 8.2|1793157|36|NZ_CP045224|CRT,CRISPRCasFinder matches to NZ_CP020426 (Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence) position: , mismatch: 1, identity: 0.972

atgtttaagtcagatggctcaccaaatcaaatgttt	CRISPR spacer
atgtttaagtcagatggttcaccaaatcaaatgttt	Protospacer
*****************.******************

181. spacer 8.2|1793157|36|NZ_CP045224|CRT,CRISPRCasFinder matches to NZ_CP029155 (Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence) position: , mismatch: 1, identity: 0.972

atgtttaagtcagatggctcaccaaatcaaatgttt	CRISPR spacer
atgtttaagtcagatggttcaccaaatcaaatgttt	Protospacer
*****************.******************

182. spacer 8.2|1793157|36|NZ_CP045224|CRT,CRISPRCasFinder matches to CP011970 (Peptoclostridium phage phiCDIF1296T strain DSM 1296, complete sequence) position: , mismatch: 1, identity: 0.972

atgtttaagtcagatggctcaccaaatcaaatgttt	CRISPR spacer
atgtttaagtcagatggttcaccaaatcaaatgttt	Protospacer
*****************.******************

183. spacer 8.2|1793157|36|NZ_CP045224|CRT,CRISPRCasFinder matches to LN681537 (Clostridium phage phiCD211, complete genome) position: , mismatch: 1, identity: 0.972

atgtttaagtcagatggctcaccaaatcaaatgttt	CRISPR spacer
atgtttaagtcagatggttcaccaaatcaaatgttt	Protospacer
*****************.******************

184. spacer 8.8|1793553|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP029155 (Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence) position: , mismatch: 1, identity: 0.972

tatagttttgtagctctttcaagttcatctgcattt	CRISPR spacer
tatagttttgtagctctctcaagttcatctgcattt	Protospacer
*****************.******************

185. spacer 8.16|1794077|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP029155 (Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence) position: , mismatch: 1, identity: 0.972

tctttagctttttctatttcagcaattatctctact	CRISPR spacer
tctttagctttttctatttcagcaattatttctact	Protospacer
*****************************.******

186. spacer 8.16|1794077|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to CP011970 (Peptoclostridium phage phiCDIF1296T strain DSM 1296, complete sequence) position: , mismatch: 1, identity: 0.972

tctttagctttttctatttcagcaattatctctact	CRISPR spacer
tctttagctttttctatttcagcaattatttctact	Protospacer
*****************************.******

187. spacer 8.16|1794077|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to LN681537 (Clostridium phage phiCD211, complete genome) position: , mismatch: 1, identity: 0.972

tctttagctttttctatttcagcaattatctctact	CRISPR spacer
tctttagctttttctatttcagcaattatttctact	Protospacer
*****************************.******

188. spacer 8.16|1794077|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP020426 (Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence) position: , mismatch: 1, identity: 0.972

tctttagctttttctatttcagcaattatctctact	CRISPR spacer
tctttagctttttctatttcagcaattatttctact	Protospacer
*****************************.******

189. spacer 8.19|1794275|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP020426 (Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence) position: , mismatch: 1, identity: 0.972

tattgaacttagcatctaatttagtatttttagtag	CRISPR spacer
tattaaacttagcatctaatttagtatttttagtag	Protospacer
****.*******************************

190. spacer 8.19|1794275|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to CP011970 (Peptoclostridium phage phiCDIF1296T strain DSM 1296, complete sequence) position: , mismatch: 1, identity: 0.972

tattgaacttagcatctaatttagtatttttagtag	CRISPR spacer
tattaaacttagcatctaatttagtatttttagtag	Protospacer
****.*******************************

191. spacer 8.19|1794275|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to LN681537 (Clostridium phage phiCD211, complete genome) position: , mismatch: 1, identity: 0.972

tattgaacttagcatctaatttagtatttttagtag	CRISPR spacer
tattaaacttagcatctaatttagtatttttagtag	Protospacer
****.*******************************

192. spacer 8.21|1794408|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to GU949551 (Clostridium phage phiCD6356, complete genome) position: , mismatch: 1, identity: 0.972

tagaaaaaagtgtacattgacaactgaatatcccct	CRISPR spacer
tagaaaaaagtgtacattaacaactgaatatcccct	Protospacer
******************.*****************

193. spacer 8.23|1794540|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP020426 (Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence) position: , mismatch: 1, identity: 0.972

tccatctacttttttacttttagctttttctttagt	CRISPR spacer
tccatctacttttttacttttagctttttctttaat	Protospacer
**********************************.*

194. spacer 8.23|1794540|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP029155 (Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence) position: , mismatch: 1, identity: 0.972

tccatctacttttttacttttagctttttctttagt	CRISPR spacer
tccatctacttttttacttttagctttttctttaat	Protospacer
**********************************.*

195. spacer 8.23|1794540|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to CP011970 (Peptoclostridium phage phiCDIF1296T strain DSM 1296, complete sequence) position: , mismatch: 1, identity: 0.972

tccatctacttttttacttttagctttttctttagt	CRISPR spacer
tccatctacttttttacttttagctttttctttaat	Protospacer
**********************************.*

196. spacer 8.23|1794540|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to LN681537 (Clostridium phage phiCD211, complete genome) position: , mismatch: 1, identity: 0.972

tccatctacttttttacttttagctttttctttagt	CRISPR spacer
tccatctacttttttacttttagctttttctttaat	Protospacer
**********************************.*

197. spacer 8.24|1794606|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP029155 (Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence) position: , mismatch: 1, identity: 0.972

agtctgaagatgagcgaatgtgctatatctgtaata	CRISPR spacer
agtctgaagatgagagaatgtgctatatctgtaata	Protospacer
************** *********************

198. spacer 8.24|1794606|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to MF547662 (Clostridioides phage LIBA6276, complete genome) position: , mismatch: 1, identity: 0.972

agtctgaagatgagcgaatgtgctatatctgtaata	CRISPR spacer
agtctgaagatgagagaatgtgctatatctgtaata	Protospacer
************** *********************

199. spacer 8.24|1794606|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to CP011970 (Peptoclostridium phage phiCDIF1296T strain DSM 1296, complete sequence) position: , mismatch: 1, identity: 0.972

agtctgaagatgagcgaatgtgctatatctgtaata	CRISPR spacer
agtctgaagatgagagaatgtgctatatctgtaata	Protospacer
************** *********************

200. spacer 8.24|1794606|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to LN681537 (Clostridium phage phiCD211, complete genome) position: , mismatch: 1, identity: 0.972

agtctgaagatgagcgaatgtgctatatctgtaata	CRISPR spacer
agtctgaagatgagagaatgtgctatatctgtaata	Protospacer
************** *********************

201. spacer 8.24|1794606|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP020426 (Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence) position: , mismatch: 1, identity: 0.972

agtctgaagatgagcgaatgtgctatatctgtaata	CRISPR spacer
agtctgaagatgagagaatgtgctatatctgtaata	Protospacer
************** *********************

202. spacer 8.37|1795462|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to NZ_MF547664 (Clostridioides difficile strain LIBA-6289 plasmid LIBA6289, complete sequence) position: , mismatch: 1, identity: 0.972

taaattattagttttaaaatttaaagggggaaaaaa	CRISPR spacer
taaattattagttttaaaatttaaagggggaaaata	Protospacer
********************************** *

203. spacer 8.38|1795528|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to LN681539 (Clostridium phage phiCD505, complete genome) position: , mismatch: 1, identity: 0.972

gctaacttaattacttgttccacatttgctaatacc	CRISPR spacer
gctaacttaattacttgttccacatttgccaatacc	Protospacer
*****************************.******

204. spacer 9.7|1906247|37|NZ_CP045224|PILER-CR matches to NZ_CP029156 (Clostridioides difficile strain CD161 plasmid unnamed2, complete sequence) position: , mismatch: 1, identity: 0.973

tttaatagcacatcttcgctttcaagtttctctatca	CRISPR spacer
tttaatagtacatcttcgctttcaagtttctctatca	Protospacer
********.****************************

205. spacer 9.7|1906247|37|NZ_CP045224|PILER-CR matches to NZ_CP029153 (Clostridioides difficile strain CDT4 plasmid unnamed1, complete sequence) position: , mismatch: 1, identity: 0.973

tttaatagcacatcttcgctttcaagtttctctatca	CRISPR spacer
tttaatagtacatcttcgctttcaagtttctctatca	Protospacer
********.****************************

206. spacer 9.17|1906118|36|NZ_CP045224|CRISPRCasFinder,CRT matches to LN681539 (Clostridium phage phiCD505, complete genome) position: , mismatch: 1, identity: 0.972

aaaggtgtgaaaagagatgagttaaatcaaagtgaa	CRISPR spacer
aaaggtgtgaaaagagatgagttaaatcaaagcgaa	Protospacer
********************************.***

207. spacer 9.17|1906118|36|NZ_CP045224|CRISPRCasFinder,CRT matches to HG531805 (Clostridium phage CDMH1 complete genome) position: , mismatch: 1, identity: 0.972

aaaggtgtgaaaagagatgagttaaatcaaagtgaa	CRISPR spacer
aaaggtgtgaaaagagatgagttaaatcaaagcgaa	Protospacer
********************************.***

208. spacer 9.17|1906118|36|NZ_CP045224|CRISPRCasFinder,CRT matches to JX145341 (Clostridium phage phiMMP02, complete genome) position: , mismatch: 1, identity: 0.972

aaaggtgtgaaaagagatgagttaaatcaaagtgaa	CRISPR spacer
aaaggtgtgaaaagagatgagttaaatcaaagcgaa	Protospacer
********************************.***

209. spacer 9.17|1906118|36|NZ_CP045224|CRISPRCasFinder,CRT matches to NC_011398 (Clostridium phage phiCD27, complete genome) position: , mismatch: 1, identity: 0.972

aaaggtgtgaaaagagatgagttaaatcaaagtgaa	CRISPR spacer
aaaggtgtgaaaagagatgagttaaatcaaagcgaa	Protospacer
********************************.***

210. spacer 9.17|1906118|36|NZ_CP045224|CRISPRCasFinder,CRT matches to NC_048642 (Clostridium phage CDKM9, complete genome) position: , mismatch: 1, identity: 0.972

aaaggtgtgaaaagagatgagttaaatcaaagtgaa	CRISPR spacer
aaaggtgtgaaaagagatgagttaaatcaaagcgaa	Protospacer
********************************.***

211. spacer 9.19|1906248|36|NZ_CP045224|CRISPRCasFinder,CRT matches to NZ_CP029156 (Clostridioides difficile strain CD161 plasmid unnamed2, complete sequence) position: , mismatch: 1, identity: 0.972

ttaatagcacatcttcgctttcaagtttctctatca	CRISPR spacer
ttaatagtacatcttcgctttcaagtttctctatca	Protospacer
*******.****************************

212. spacer 9.19|1906248|36|NZ_CP045224|CRISPRCasFinder,CRT matches to NZ_CP029153 (Clostridioides difficile strain CDT4 plasmid unnamed1, complete sequence) position: , mismatch: 1, identity: 0.972

ttaatagcacatcttcgctttcaagtttctctatca	CRISPR spacer
ttaatagtacatcttcgctttcaagtttctctatca	Protospacer
*******.****************************

213. spacer 10.10|2319383|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to MK473382 (Clostridium phage JD032, complete genome) position: , mismatch: 1, identity: 0.973

ttttaaataacccccctccccttctga-ttttttcgtg	CRISPR spacer
ttttaaataacccccctccccttctgatttttttcgt-	Protospacer
*************************** *********

214. spacer 12.7|2802740|38|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MG266000 (Clostridioides difficile strain 7032985 plasmid pCD-ISS1, complete sequence) position: , mismatch: 1, identity: 0.974

gtcttttcaatctgttcaactaccttaggttcattcag	CRISPR spacer
gtcttttcaatctgttcaactaccttaggttcatttag	Protospacer
***********************************.**

215. spacer 1.7|337392|22|NZ_CP045224|CRT matches to MH285980 (Escherichia phage Eco_BIFF, complete genome) position: , mismatch: 2, identity: 0.909

tgcaactggagcaacaggattt	CRISPR spacer
tgcaactgtagcaacaggatta	Protospacer
******** ************

216. spacer 1.7|337392|22|NZ_CP045224|CRT matches to NZ_LT969521 (Pseudomonas aeruginosa isolate RW109 genome assembly, plasmid: RW109 plasmid 2) position: , mismatch: 2, identity: 0.909

tgcaactggagcaacaggattt	CRISPR spacer
ggcaactggagcaacaggatat	Protospacer
 ******************* *

217. spacer 1.7|337392|22|NZ_CP045224|CRT matches to NC_047959 (Enterobacteria phage vB_EcoS_IME18, complete genome) position: , mismatch: 2, identity: 0.909

tgcaactggagcaacaggattt	CRISPR spacer
tgcaactgtagcaacaggatta	Protospacer
******** ************

218. spacer 3.3|779113|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to LN681539 (Clostridium phage phiCD505, complete genome) position: , mismatch: 2, identity: 0.944

atatctttgtactcttgattttccagctttgatata	CRISPR spacer
atatctttgtactcttgattttctagttttgatata	Protospacer
***********************.**.*********

219. spacer 3.3|779113|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to JX145341 (Clostridium phage phiMMP02, complete genome) position: , mismatch: 2, identity: 0.944

atatctttgtactcttgattttccagctttgatata	CRISPR spacer
atatctttgtactcttgattttctagttttgatata	Protospacer
***********************.**.*********

220. spacer 3.6|779309|34|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to LN681538 (Clostridium phage phiCD481-1, complete genome) position: , mismatch: 2, identity: 0.941

ttgcttatacttacaactttttctgctgtagcat	CRISPR spacer
ttgcttatacttacatttttttctgctgtagcat	Protospacer
*************** .*****************

221. spacer 3.7|779372|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_028996 (Clostridium phage phiCDHM19, complete genome) position: , mismatch: 2, identity: 0.944

aaaactgtttctacttttttagtcccaagtaattcc	CRISPR spacer
aaaattgtttctacttttttagtaccaagtaattcc	Protospacer
****.****************** ************

222. spacer 3.7|779372|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to JX145341 (Clostridium phage phiMMP02, complete genome) position: , mismatch: 2, identity: 0.944

aaaactgtttctacttttttagtcccaagtaattcc	CRISPR spacer
aaaattgtttctacttttttagtctcaagtaattcc	Protospacer
****.*******************.***********

223. spacer 3.8|779437|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to AY855346 (Clostridium difficile bacteriophage phi CD119, complete genome) position: , mismatch: 2, identity: 0.946

cgcatttttgcttttatattgcttcttctatcttcta	CRISPR spacer
ctcatttttgcttttatattacttcttctatcttcta	Protospacer
* ******************.****************

224. spacer 3.8|779437|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_048665 (Clostridium phage phiCDHM14, complete genome) position: , mismatch: 2, identity: 0.946

cgcatttttgcttttatattgcttcttctatcttcta	CRISPR spacer
cgcatctttgcttttatattacttcttctatcttcta	Protospacer
*****.**************.****************

225. spacer 3.8|779437|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_007917 (Clostridium phage phi CD119, complete genome) position: , mismatch: 2, identity: 0.946

cgcatttttgcttttatattgcttcttctatcttcta	CRISPR spacer
ctcatttttgcttttatattacttcttctatcttcta	Protospacer
* ******************.****************

226. spacer 3.8|779437|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_028996 (Clostridium phage phiCDHM19, complete genome) position: , mismatch: 2, identity: 0.946

cgcatttttgcttttatattgcttcttctatcttcta	CRISPR spacer
ctcatttttgcttttatattacttcttctatcttcta	Protospacer
* ******************.****************

227. spacer 3.8|779437|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to MK473382 (Clostridium phage JD032, complete genome) position: , mismatch: 2, identity: 0.946

cgcatttttgcttttatattgcttcttctatcttcta	CRISPR spacer
ctcatttttgcttttatattacttcttctatcttcta	Protospacer
* ******************.****************

228. spacer 3.8|779437|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to HG796225 (Clostridium phage phiCDHM13 complete genome) position: , mismatch: 2, identity: 0.946

cgcatttttgcttttatattgcttcttctatcttcta	CRISPR spacer
cgcatctttgcttttatattacttcttctatcttcta	Protospacer
*****.**************.****************

229. spacer 3.8|779437|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to LN681538 (Clostridium phage phiCD481-1, complete genome) position: , mismatch: 2, identity: 0.946

cgcatttttgcttttatattgcttcttctatcttcta	CRISPR spacer
ctcatttttgcttttatattacttcttctatcttcta	Protospacer
* ******************.****************

230. spacer 3.8|779437|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to HG798901 (Clostridium phage phiCDHM11 complete genome) position: , mismatch: 2, identity: 0.946

cgcatttttgcttttatattgcttcttctatcttcta	CRISPR spacer
cgcatctttgcttttatattacttcttctatcttcta	Protospacer
*****.**************.****************

231. spacer 3.25|780551|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to GU949551 (Clostridium phage phiCD6356, complete genome) position: , mismatch: 2, identity: 0.944

cagttgacacaatgagtaaaagcgaagcagagcaag	CRISPR spacer
cagttgttacaatgagtaaaagcgaagcagagcaag	Protospacer
****** .****************************

232. spacer 3.27|780682|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to AY855346 (Clostridium difficile bacteriophage phi CD119, complete genome) position: , mismatch: 2, identity: 0.946

catagattttggagatttaagggaaggcaatatgtgt	CRISPR spacer
tatagattttggagatttaagagaaggcaatatgtgt	Protospacer
.********************.***************

233. spacer 3.27|780682|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_007917 (Clostridium phage phi CD119, complete genome) position: , mismatch: 2, identity: 0.946

catagattttggagatttaagggaaggcaatatgtgt	CRISPR spacer
tatagattttggagatttaagagaaggcaatatgtgt	Protospacer
.********************.***************

234. spacer 3.27|780682|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to HG531805 (Clostridium phage CDMH1 complete genome) position: , mismatch: 2, identity: 0.946

catagattttggagatttaagggaaggcaatatgtgt	CRISPR spacer
tatagattttggagatttaagagaaggcaatatgtgt	Protospacer
.********************.***************

235. spacer 7.1|1068974|38|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_011398 (Clostridium phage phiCD27, complete genome) position: , mismatch: 2, identity: 0.947

tagactgatattcatccatactgatgattcctaaagaa	CRISPR spacer
tagaatgatattcatccatgctgatgattcctaaagaa	Protospacer
**** **************.******************

236. spacer 7.5|1069236|38|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to HG531805 (Clostridium phage CDMH1 complete genome) position: , mismatch: 2, identity: 0.947

aaataagttttgaagcagaatttacacacaataaacta	CRISPR spacer
aaataagttttgaagcagagtttacacacaataaatta	Protospacer
*******************.***************.**

237. spacer 7.14|1069830|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to MN718463 (Clostridium phage phiCDKH01, complete genome) position: , mismatch: 2, identity: 0.946

tcattataaccccaaccaactacagttgcagggattt	CRISPR spacer
tcattataaccccagccaacaacagttgcagggattt	Protospacer
**************.***** ****************

238. spacer 7.14|1069830|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_048642 (Clostridium phage CDKM9, complete genome) position: , mismatch: 2, identity: 0.946

tcattataaccccaaccaactacagttgcagggattt	CRISPR spacer
tcattataaccccatccaacaacagttgcagggattt	Protospacer
************** ***** ****************

239. spacer 7.28|1070754|38|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_048665 (Clostridium phage phiCDHM14, complete genome) position: , mismatch: 2, identity: 0.947

gaatctggagcaggtttataagtttctggatagctaga	CRISPR spacer
gaatccggagcaggtttataagtttcgggatagctaga	Protospacer
*****.******************** ***********

240. spacer 7.28|1070754|38|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to HG796225 (Clostridium phage phiCDHM13 complete genome) position: , mismatch: 2, identity: 0.947

gaatctggagcaggtttataagtttctggatagctaga	CRISPR spacer
gaatccggagcaggtttataagtttcgggatagctaga	Protospacer
*****.******************** ***********

241. spacer 7.28|1070754|38|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to HG798901 (Clostridium phage phiCDHM11 complete genome) position: , mismatch: 2, identity: 0.947

gaatctggagcaggtttataagtttctggatagctaga	CRISPR spacer
gaatccggagcaggtttataagtttcgggatagctaga	Protospacer
*****.******************** ***********

242. spacer 7.29|1070821|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to MK473382 (Clostridium phage JD032, complete genome) position: , mismatch: 2, identity: 0.944

aaaaaatataaaagagctaagcacatgaaggataat	CRISPR spacer
aaaaaatacaaaagagctaagcacatgaaagataat	Protospacer
********.********************.******

243. spacer 7.29|1070821|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_048665 (Clostridium phage phiCDHM14, complete genome) position: , mismatch: 2, identity: 0.944

aaaaaatataaaagagctaagcacatgaaggataat	CRISPR spacer
aaaaaatacaaaagagctaagcacatgaaagataat	Protospacer
********.********************.******

244. spacer 7.29|1070821|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to HG796225 (Clostridium phage phiCDHM13 complete genome) position: , mismatch: 2, identity: 0.944

aaaaaatataaaagagctaagcacatgaaggataat	CRISPR spacer
aaaaaatacaaaagagctaagcacatgaaagataat	Protospacer
********.********************.******

245. spacer 7.29|1070821|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to HG798901 (Clostridium phage phiCDHM11 complete genome) position: , mismatch: 2, identity: 0.944

aaaaaatataaaagagctaagcacatgaaggataat	CRISPR spacer
aaaaaatacaaaagagctaagcacatgaaagataat	Protospacer
********.********************.******

246. spacer 7.37|1071348|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to KX905163 (Clostridioides phage phiSemix9P1, complete genome) position: , mismatch: 2, identity: 0.944

attaattcagaacttgcacagttgtatatagaactt	CRISPR spacer
gttaattcagaacttgcacagttatatatagaactt	Protospacer
.**********************.************

247. spacer 8.3|1793223|36|NZ_CP045224|CRT,CRISPRCasFinder matches to CP011970 (Peptoclostridium phage phiCDIF1296T strain DSM 1296, complete sequence) position: , mismatch: 2, identity: 0.944

tttattgtagctgttataacttctttatttgtatta	CRISPR spacer
tttattgtagcttgtataacttctttatttgtatta	Protospacer
************  **********************

248. spacer 8.3|1793223|36|NZ_CP045224|CRT,CRISPRCasFinder matches to LN681537 (Clostridium phage phiCD211, complete genome) position: , mismatch: 2, identity: 0.944

tttattgtagctgttataacttctttatttgtatta	CRISPR spacer
tttattgtagcttgtataacttctttatttgtatta	Protospacer
************  **********************

249. spacer 8.3|1793223|36|NZ_CP045224|CRT,CRISPRCasFinder matches to NZ_CP020426 (Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence) position: , mismatch: 2, identity: 0.944

tttattgtagctgttataacttctttatttgtatta	CRISPR spacer
tttattgtagcttgtataacttctttatttgtatta	Protospacer
************  **********************

250. spacer 8.8|1793553|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to CP011970 (Peptoclostridium phage phiCDIF1296T strain DSM 1296, complete sequence) position: , mismatch: 2, identity: 0.944

tatagttttgtagctctttcaagttcatctgcattt	CRISPR spacer
tatagttttgtagctctctcaagctcatctgcattt	Protospacer
*****************.*****.************

251. spacer 8.8|1793553|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to LN681537 (Clostridium phage phiCD211, complete genome) position: , mismatch: 2, identity: 0.944

tatagttttgtagctctttcaagttcatctgcattt	CRISPR spacer
tatagttttgtagctctctcaagctcatctgcattt	Protospacer
*****************.*****.************

252. spacer 8.8|1793553|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP020426 (Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence) position: , mismatch: 2, identity: 0.944

tatagttttgtagctctttcaagttcatctgcattt	CRISPR spacer
tatagttttgtagctctctcaagctcatctgcattt	Protospacer
*****************.*****.************

253. spacer 8.24|1794606|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to MF547663 (Clostridioides phage LIBA2945, complete genome) position: , mismatch: 2, identity: 0.944

agtctgaagatgagcgaatgtgctatatctgtaata	CRISPR spacer
agtctgaagatgagcgaatgtgttatatctgtaatg	Protospacer
**********************.************.

254. spacer 9.5|1906117|37|NZ_CP045224|PILER-CR matches to LN681539 (Clostridium phage phiCD505, complete genome) position: , mismatch: 2, identity: 0.946

taaaggtgtgaaaagagatgagttaaatcaaagtgaa	CRISPR spacer
aaaaggtgtgaaaagagatgagttaaatcaaagcgaa	Protospacer
 ********************************.***

255. spacer 9.5|1906117|37|NZ_CP045224|PILER-CR matches to HG531805 (Clostridium phage CDMH1 complete genome) position: , mismatch: 2, identity: 0.946

taaaggtgtgaaaagagatgagttaaatcaaagtgaa	CRISPR spacer
aaaaggtgtgaaaagagatgagttaaatcaaagcgaa	Protospacer
 ********************************.***

256. spacer 9.5|1906117|37|NZ_CP045224|PILER-CR matches to JX145341 (Clostridium phage phiMMP02, complete genome) position: , mismatch: 2, identity: 0.946

taaaggtgtgaaaagagatgagttaaatcaaagtgaa	CRISPR spacer
aaaaggtgtgaaaagagatgagttaaatcaaagcgaa	Protospacer
 ********************************.***

257. spacer 9.5|1906117|37|NZ_CP045224|PILER-CR matches to NC_011398 (Clostridium phage phiCD27, complete genome) position: , mismatch: 2, identity: 0.946

taaaggtgtgaaaagagatgagttaaatcaaagtgaa	CRISPR spacer
aaaaggtgtgaaaagagatgagttaaatcaaagcgaa	Protospacer
 ********************************.***

258. spacer 9.5|1906117|37|NZ_CP045224|PILER-CR matches to NC_048642 (Clostridium phage CDKM9, complete genome) position: , mismatch: 2, identity: 0.946

taaaggtgtgaaaagagatgagttaaatcaaagtgaa	CRISPR spacer
aaaaggtgtgaaaagagatgagttaaatcaaagcgaa	Protospacer
 ********************************.***

259. spacer 9.20|1906313|37|NZ_CP045224|CRISPRCasFinder,CRT matches to NC_048665 (Clostridium phage phiCDHM14, complete genome) position: , mismatch: 2, identity: 0.946

tatatattggatgtcaatgtcaagaatacaaaattta	CRISPR spacer
tatatattagatatcaatgtcaagaatacaaaattta	Protospacer
********.***.************************

260. spacer 9.20|1906313|37|NZ_CP045224|CRISPRCasFinder,CRT matches to MK473382 (Clostridium phage JD032, complete genome) position: , mismatch: 2, identity: 0.946

tatatattggatgtcaatgtcaagaatacaaaattta	CRISPR spacer
tatatattagatatcaatgtcaagaatacaaaattta	Protospacer
********.***.************************

261. spacer 9.20|1906313|37|NZ_CP045224|CRISPRCasFinder,CRT matches to HG796225 (Clostridium phage phiCDHM13 complete genome) position: , mismatch: 2, identity: 0.946

tatatattggatgtcaatgtcaagaatacaaaattta	CRISPR spacer
tatatattagatatcaatgtcaagaatacaaaattta	Protospacer
********.***.************************

262. spacer 9.20|1906313|37|NZ_CP045224|CRISPRCasFinder,CRT matches to HG798901 (Clostridium phage phiCDHM11 complete genome) position: , mismatch: 2, identity: 0.946

tatatattggatgtcaatgtcaagaatacaaaattta	CRISPR spacer
tatatattagatatcaatgtcaagaatacaaaattta	Protospacer
********.***.************************

263. spacer 10.9|2319317|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_048665 (Clostridium phage phiCDHM14, complete genome) position: , mismatch: 2, identity: 0.946

cttgatgtttagctttttgaaataattcaagttttaa	CRISPR spacer
cttgatgtttagccttttgaaataattcaagtttcaa	Protospacer
*************.********************.**

264. spacer 10.9|2319317|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to JX145342 (Clostridium phage phiMMP04, complete genome) position: , mismatch: 2, identity: 0.946

cttgatgtttagctttttgaaataattcaagttttaa	CRISPR spacer
cttgatgtttcgctttttgaaataattcaagctttaa	Protospacer
********** ********************.*****

265. spacer 10.9|2319317|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to HG796225 (Clostridium phage phiCDHM13 complete genome) position: , mismatch: 2, identity: 0.946

cttgatgtttagctttttgaaataattcaagttttaa	CRISPR spacer
cttgatgtttagccttttgaaataattcaagtttcaa	Protospacer
*************.********************.**

266. spacer 10.9|2319317|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to HG798901 (Clostridium phage phiCDHM11 complete genome) position: , mismatch: 2, identity: 0.946

cttgatgtttagctttttgaaataattcaagttttaa	CRISPR spacer
cttgatgtttagccttttgaaataattcaagtttcaa	Protospacer
*************.********************.**

267. spacer 10.10|2319383|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_048665 (Clostridium phage phiCDHM14, complete genome) position: , mismatch: 2, identity: 0.946

ttttaaataacccccctccccttctgattttttcgtg	CRISPR spacer
ttttaaataacccccctcccattctgattttttcatg	Protospacer
******************** *************.**

268. spacer 10.10|2319383|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to JX145342 (Clostridium phage phiMMP04, complete genome) position: , mismatch: 2, identity: 0.946

ttttaaataacccccctccccttctgattttttcgtg	CRISPR spacer
ttttaaataacccccctcccattctgattttttcatg	Protospacer
******************** *************.**

269. spacer 10.10|2319383|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_028838 (Clostridium phage phiCD506, complete genome) position: , mismatch: 2, identity: 0.946

ttttaaataacccccctccccttctgattttttcgtg	CRISPR spacer
ttttaaataacccccctcccattctgattttttcatg	Protospacer
******************** *************.**

270. spacer 10.10|2319383|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to HG796225 (Clostridium phage phiCDHM13 complete genome) position: , mismatch: 2, identity: 0.946

ttttaaataacccccctccccttctgattttttcgtg	CRISPR spacer
ttttaaataacccccctcccattctgattttttcatg	Protospacer
******************** *************.**

271. spacer 10.10|2319383|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to LN681538 (Clostridium phage phiCD481-1, complete genome) position: , mismatch: 2, identity: 0.946

ttttaaataacccccctccccttctgattttttcgtg	CRISPR spacer
ttttaaataacccccctcccattctgattttttcatg	Protospacer
******************** *************.**

272. spacer 10.10|2319383|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to HG798901 (Clostridium phage phiCDHM11 complete genome) position: , mismatch: 2, identity: 0.946

ttttaaataacccccctccccttctgattttttcgtg	CRISPR spacer
ttttaaataacccccctcccattctgattttttcatg	Protospacer
******************** *************.**

273. spacer 10.14|2319646|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to JX145342 (Clostridium phage phiMMP04, complete genome) position: , mismatch: 2, identity: 0.944

gaactaacctcgtttcctgtgttaataaactatgat	CRISPR spacer
gaactaacctcgtttcctgtgttaacaagctatgat	Protospacer
*************************.**.*******

274. spacer 10.16|2319777|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to LN681539 (Clostridium phage phiCD505, complete genome) position: , mismatch: 2, identity: 0.946

agtttatttggggattagataaaaataaggtagcatc	CRISPR spacer
agtttatttggggattagatggaaataaggtagcatc	Protospacer
********************..***************

275. spacer 12.5|2802607|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020425 (Clostridioides difficile strain FDAARGOS_267 plasmid unnamed1, complete sequence) position: , mismatch: 2, identity: 0.946

caatatccatttctccttttccagcaatattaaattt	CRISPR spacer
cgatatccatttctccttttccagtaatattaaattt	Protospacer
*.**********************.************

276. spacer 12.5|2802607|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029156 (Clostridioides difficile strain CD161 plasmid unnamed2, complete sequence) position: , mismatch: 2, identity: 0.946

caatatccatttctccttttccagcaatattaaattt	CRISPR spacer
cgatatccatttctccttttccagtaatattaaattt	Protospacer
*.**********************.************

277. spacer 12.5|2802607|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029153 (Clostridioides difficile strain CDT4 plasmid unnamed1, complete sequence) position: , mismatch: 2, identity: 0.946

caatatccatttctccttttccagcaatattaaattt	CRISPR spacer
cgatatccatttctccttttccagtaatattaaattt	Protospacer
*.**********************.************

278. spacer 12.5|2802607|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to FN668942 (Clostridium difficile BI1 plasmid pCDBI1, complete sequence) position: , mismatch: 2, identity: 0.946

caatatccatttctccttttccagcaatattaaattt	CRISPR spacer
cgatatccatttctccttttccagtaatattaaattt	Protospacer
*.**********************.************

279. spacer 12.5|2802607|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP011969 (Clostridioides difficile ATCC 9689 = DSM 1296 plasmid unnamed, complete sequence) position: , mismatch: 2, identity: 0.946

caatatccatttctccttttccagcaatattaaattt	CRISPR spacer
cgatatccatttctccttttccagtaatattaaattt	Protospacer
*.**********************.************

280. spacer 12.8|2802807|38|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_008226 (Clostridioides difficile 630 plasmid pCD630, complete sequence) position: , mismatch: 2, identity: 0.947

cttatacttccgttattaaacatcatatctgctattat	CRISPR spacer
cttatacttccgttattaaacattatatctgctatcat	Protospacer
***********************.***********.**

281. spacer 12.8|2802807|38|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016319 (Clostridioides difficile strain 630 delta erm plasmid pCD630, complete sequence) position: , mismatch: 2, identity: 0.947

cttatacttccgttattaaacatcatatctgctattat	CRISPR spacer
cttatacttccgttattaaacattatatctgctatcat	Protospacer
***********************.***********.**

282. spacer 15.1|4054099|38|NZ_CP045224|CRISPRCasFinder matches to NZ_CP033215 (Clostridioides difficile strain 12038 plasmid unnamed1, complete sequence) position: , mismatch: 2, identity: 0.947

aaacaaacttcagatgcgttcagtttattctgttgctt	CRISPR spacer
aaacaaacttcacatgtgttcagtttattctgttgctt	Protospacer
************ ***.*********************

283. spacer 1.7|337392|22|NZ_CP045224|CRT matches to NC_028998 (Phormidium phage MIS-PhV1B, complete genome) position: , mismatch: 3, identity: 0.864

tgcaactggagcaacaggattt	CRISPR spacer
tgcaactggagcaacaggagcg	Protospacer
******************* .

284. spacer 2.14|455268|27|NZ_CP045224|CRT matches to MN693816 (Marine virus AFVG_250M124, complete genome) position: , mismatch: 3, identity: 0.889

gcgacaggagcgacaggggcaaatgga	CRISPR spacer
gcgacaggagcgacaggagcaactggt	Protospacer
*****************.**** ***

285. spacer 3.8|779437|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to JX145342 (Clostridium phage phiMMP04, complete genome) position: , mismatch: 3, identity: 0.919

cgcatttttgcttttatattgcttcttctatcttcta	CRISPR spacer
ctcatctttgcttttatattacttcttctatcttcta	Protospacer
* ***.**************.****************

286. spacer 3.8|779437|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_028838 (Clostridium phage phiCD506, complete genome) position: , mismatch: 3, identity: 0.919

cgcatttttgcttttatattgcttcttctatcttcta	CRISPR spacer
ctcatctttgcttttatattacttcttctatcttcta	Protospacer
* ***.**************.****************

287. spacer 3.19|780162|35|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020426 (Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence) position: , mismatch: 3, identity: 0.914

gcataaaataccttcaaaaatagcttctactgaca	CRISPR spacer
acataaaataccttcaaaaacagcttctattgaca	Protospacer
.*******************.********.*****

288. spacer 3.19|780162|35|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029155 (Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.914

gcataaaataccttcaaaaatagcttctactgaca	CRISPR spacer
acataaaataccttcaaaaacagcttctattgaca	Protospacer
.*******************.********.*****

289. spacer 3.19|780162|35|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to MF547662 (Clostridioides phage LIBA6276, complete genome) position: , mismatch: 3, identity: 0.914

gcataaaataccttcaaaaatagcttctactgaca	CRISPR spacer
acataaaataccttcaaaaacagcttctattgaca	Protospacer
.*******************.********.*****

290. spacer 3.19|780162|35|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to MF547663 (Clostridioides phage LIBA2945, complete genome) position: , mismatch: 3, identity: 0.914

gcataaaataccttcaaaaatagcttctactgaca	CRISPR spacer
acataaaataccttcaaaaacagcttctattgaca	Protospacer
.*******************.********.*****

291. spacer 3.19|780162|35|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to CP011970 (Peptoclostridium phage phiCDIF1296T strain DSM 1296, complete sequence) position: , mismatch: 3, identity: 0.914

gcataaaataccttcaaaaatagcttctactgaca	CRISPR spacer
acataaaataccttcaaaaacagcttctattgaca	Protospacer
.*******************.********.*****

292. spacer 3.19|780162|35|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to LN681537 (Clostridium phage phiCD211, complete genome) position: , mismatch: 3, identity: 0.914

gcataaaataccttcaaaaatagcttctactgaca	CRISPR spacer
acataaaataccttcaaaaacagcttctattgaca	Protospacer
.*******************.********.*****

293. spacer 7.19|1070163|35|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to AY855346 (Clostridium difficile bacteriophage phi CD119, complete genome) position: , mismatch: 3, identity: 0.914

atatgacagcacaaggaacacctacagcacaagca	CRISPR spacer
acatgacagcacaagggacacctacagcacaagcc	Protospacer
*.**************.*****************

294. spacer 7.19|1070163|35|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_007917 (Clostridium phage phi CD119, complete genome) position: , mismatch: 3, identity: 0.914

atatgacagcacaaggaacacctacagcacaagca	CRISPR spacer
acatgacagcacaagggacacctacagcacaagcc	Protospacer
*.**************.*****************

295. spacer 7.19|1070163|35|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_028996 (Clostridium phage phiCDHM19, complete genome) position: , mismatch: 3, identity: 0.914

atatgacagcacaaggaacacctacagcacaagca	CRISPR spacer
acatgacagcacaagggacacctacagcacaagcc	Protospacer
*.**************.*****************

296. spacer 8.21|1794408|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to NC_028838 (Clostridium phage phiCD506, complete genome) position: , mismatch: 3, identity: 0.917

tagaaaaaagtgtacattgacaactgaatatcccct	CRISPR spacer
tagaaaaaagtgtacattgacaactgaatattcctc	Protospacer
*******************************.**..

297. spacer 8.25|1794672|37|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP029155 (Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.919

ttaaatataataaatcgtaatgtacaaaaataactta-	CRISPR spacer
ttaaatataagaaatcataatgtac-aaaataacttat	Protospacer
********** *****.******** ***********

298. spacer 8.25|1794672|37|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to MF547662 (Clostridioides phage LIBA6276, complete genome) position: , mismatch: 3, identity: 0.919

ttaaatataataaatcgtaatgtacaaaaataactta-	CRISPR spacer
ttaaatataagaaatcataatgtac-aaaataacttat	Protospacer
********** *****.******** ***********

299. spacer 8.25|1794672|37|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to MF547663 (Clostridioides phage LIBA2945, complete genome) position: , mismatch: 3, identity: 0.919

ttaaatataataaatcgtaatgtacaaaaataactta-	CRISPR spacer
ttaaatataagaaatcataatgtac-aaaataacttat	Protospacer
********** *****.******** ***********

300. spacer 9.3|1905986|39|NZ_CP045224|PILER-CR matches to AY855346 (Clostridium difficile bacteriophage phi CD119, complete genome) position: , mismatch: 3, identity: 0.923

ttggaaactaata---tttatataaaacttgtaaatatacag	CRISPR spacer
---gaaactaataatgtttatataaaacttgtaaatatacag	Protospacer
   **********   **************************

301. spacer 9.3|1905986|39|NZ_CP045224|PILER-CR matches to NC_007917 (Clostridium phage phi CD119, complete genome) position: , mismatch: 3, identity: 0.923

ttggaaactaata---tttatataaaacttgtaaatatacag	CRISPR spacer
---gaaactaataatgtttatataaaacttgtaaatatacag	Protospacer
   **********   **************************

302. spacer 9.3|1905986|39|NZ_CP045224|PILER-CR matches to NC_028996 (Clostridium phage phiCDHM19, complete genome) position: , mismatch: 3, identity: 0.923

ttggaaactaata---tttatataaaacttgtaaatatacag	CRISPR spacer
---gaaactaataatgtttatataaaacttgtaaatatacag	Protospacer
   **********   **************************

303. spacer 9.3|1905986|39|NZ_CP045224|PILER-CR matches to LN681542 (Clostridium phage phiMMP03, complete genome) position: , mismatch: 3, identity: 0.923

ttggaaactaata---tttatataaaacttgtaaatatacag	CRISPR spacer
---gaaactaataatgtttatataaaacttgtaaatatacag	Protospacer
   **********   **************************

304. spacer 9.3|1905986|39|NZ_CP045224|PILER-CR matches to NC_009231 (Clostridium phage phiC2, complete genome) position: , mismatch: 3, identity: 0.923

ttggaaactaata---tttatataaaacttgtaaatatacag	CRISPR spacer
---gaaactaataatgtttatataaaacttgtaaatatacag	Protospacer
   **********   **************************

305. spacer 9.3|1905986|39|NZ_CP045224|PILER-CR matches to JX145341 (Clostridium phage phiMMP02, complete genome) position: , mismatch: 3, identity: 0.923

ttggaaactaata---tttatataaaacttgtaaatatacag	CRISPR spacer
---gaaactaataatgtttatataaaacttgtaaatatacag	Protospacer
   **********   **************************

306. spacer 9.3|1905986|39|NZ_CP045224|PILER-CR matches to NC_011398 (Clostridium phage phiCD27, complete genome) position: , mismatch: 3, identity: 0.923

ttggaaactaata---tttatataaaacttgtaaatatacag	CRISPR spacer
---gaaactaataatgtttatataaaacttgtaaatatacag	Protospacer
   **********   **************************

307. spacer 9.3|1905986|39|NZ_CP045224|PILER-CR matches to KX228400 (Clostridium phage CDKM15, complete genome) position: , mismatch: 3, identity: 0.923

ttggaaactaata---tttatataaaacttgtaaatatacag	CRISPR spacer
---gaaactaataatgtttatataaaacttgtaaatatacag	Protospacer
   **********   **************************

308. spacer 9.8|1906312|38|NZ_CP045224|PILER-CR matches to MK473382 (Clostridium phage JD032, complete genome) position: , mismatch: 3, identity: 0.921

ttatatattggatgtcaatgtcaagaatacaaaattta	CRISPR spacer
atatatattagatatcaatgtcaagaatacaaaattta	Protospacer
 ********.***.************************

309. spacer 9.8|1906312|38|NZ_CP045224|PILER-CR matches to NC_048665 (Clostridium phage phiCDHM14, complete genome) position: , mismatch: 3, identity: 0.921

ttatatattggatgtcaatgtcaagaatacaaaattta	CRISPR spacer
atatatattagatatcaatgtcaagaatacaaaattta	Protospacer
 ********.***.************************

310. spacer 9.8|1906312|38|NZ_CP045224|PILER-CR matches to HG796225 (Clostridium phage phiCDHM13 complete genome) position: , mismatch: 3, identity: 0.921

ttatatattggatgtcaatgtcaagaatacaaaattta	CRISPR spacer
atatatattagatatcaatgtcaagaatacaaaattta	Protospacer
 ********.***.************************

311. spacer 9.8|1906312|38|NZ_CP045224|PILER-CR matches to HG798901 (Clostridium phage phiCDHM11 complete genome) position: , mismatch: 3, identity: 0.921

ttatatattggatgtcaatgtcaagaatacaaaattta	CRISPR spacer
atatatattagatatcaatgtcaagaatacaaaattta	Protospacer
 ********.***.************************

312. spacer 9.15|1905987|38|NZ_CP045224|CRISPRCasFinder,CRT matches to AY855346 (Clostridium difficile bacteriophage phi CD119, complete genome) position: , mismatch: 3, identity: 0.921

tggaaactaata---tttatataaaacttgtaaatatacag	CRISPR spacer
---aaactaataatgtttatataaaacttgtaaatatacag	Protospacer
   *********   **************************

313. spacer 9.15|1905987|38|NZ_CP045224|CRISPRCasFinder,CRT matches to NC_007917 (Clostridium phage phi CD119, complete genome) position: , mismatch: 3, identity: 0.921

tggaaactaata---tttatataaaacttgtaaatatacag	CRISPR spacer
---aaactaataatgtttatataaaacttgtaaatatacag	Protospacer
   *********   **************************

314. spacer 9.15|1905987|38|NZ_CP045224|CRISPRCasFinder,CRT matches to NC_028996 (Clostridium phage phiCDHM19, complete genome) position: , mismatch: 3, identity: 0.921

tggaaactaata---tttatataaaacttgtaaatatacag	CRISPR spacer
---aaactaataatgtttatataaaacttgtaaatatacag	Protospacer
   *********   **************************

315. spacer 9.15|1905987|38|NZ_CP045224|CRISPRCasFinder,CRT matches to LN681542 (Clostridium phage phiMMP03, complete genome) position: , mismatch: 3, identity: 0.921

tggaaactaata---tttatataaaacttgtaaatatacag	CRISPR spacer
---aaactaataatgtttatataaaacttgtaaatatacag	Protospacer
   *********   **************************

316. spacer 9.15|1905987|38|NZ_CP045224|CRISPRCasFinder,CRT matches to NC_009231 (Clostridium phage phiC2, complete genome) position: , mismatch: 3, identity: 0.921

tggaaactaata---tttatataaaacttgtaaatatacag	CRISPR spacer
---aaactaataatgtttatataaaacttgtaaatatacag	Protospacer
   *********   **************************

317. spacer 9.15|1905987|38|NZ_CP045224|CRISPRCasFinder,CRT matches to JX145341 (Clostridium phage phiMMP02, complete genome) position: , mismatch: 3, identity: 0.921

tggaaactaata---tttatataaaacttgtaaatatacag	CRISPR spacer
---aaactaataatgtttatataaaacttgtaaatatacag	Protospacer
   *********   **************************

318. spacer 9.15|1905987|38|NZ_CP045224|CRISPRCasFinder,CRT matches to NC_011398 (Clostridium phage phiCD27, complete genome) position: , mismatch: 3, identity: 0.921

tggaaactaata---tttatataaaacttgtaaatatacag	CRISPR spacer
---aaactaataatgtttatataaaacttgtaaatatacag	Protospacer
   *********   **************************

319. spacer 9.15|1905987|38|NZ_CP045224|CRISPRCasFinder,CRT matches to KX228400 (Clostridium phage CDKM15, complete genome) position: , mismatch: 3, identity: 0.921

tggaaactaata---tttatataaaacttgtaaatatacag	CRISPR spacer
---aaactaataatgtttatataaaacttgtaaatatacag	Protospacer
   *********   **************************

320. spacer 12.2|2802409|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to GU949551 (Clostridium phage phiCD6356, complete genome) position: , mismatch: 3, identity: 0.919

aagataaaagtgaaatatctgaatatatagaaaaact	CRISPR spacer
aagacaaaagtgaaatatctgagtatatagaaaaaat	Protospacer
****.*****************.************ *

321. spacer 12.4|2802541|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_005326 ([Clostridium] difficile plasmid pCD6, complete sequence) position: , mismatch: 3, identity: 0.919

tgtcccaaaatagcatcattactttaagttcagcatt	CRISPR spacer
tatcccaaaatagcatcattactttaagttcagcacg	Protospacer
*.*********************************.

322. spacer 10.8|2319251|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_009231 (Clostridium phage phiC2, complete genome) position: , mismatch: 4, identity: 0.892

aagaaggtgaaataatattctatgaagggcaattaaa	CRISPR spacer
aagaaggcgaaataatattctatgaaggacaatcgaa	Protospacer
*******.********************.****..**

323. spacer 10.9|2319317|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to MK473382 (Clostridium phage JD032, complete genome) position: , mismatch: 4, identity: 0.892

cttgatgtttagctttttgaaataattcaagttttaa	CRISPR spacer
cttgatgtttggctttttgaaatagttcaagtttaag	Protospacer
**********.*************.********* *.

324. spacer 10.9|2319317|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_028838 (Clostridium phage phiCD506, complete genome) position: , mismatch: 4, identity: 0.892

cttgatgtttagctttttgaaataattcaagttttaa	CRISPR spacer
cttgatgtttagctttctgaaataattcaagcctcaa	Protospacer
****************.**************..*.**

325. spacer 10.9|2319317|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to LN681538 (Clostridium phage phiCD481-1, complete genome) position: , mismatch: 4, identity: 0.892

cttgatgtttagctttttgaaataattcaagttttaa	CRISPR spacer
cttgatgtttagctttctgaaataattcaagcctcaa	Protospacer
****************.**************..*.**

326. spacer 13.5|3182527|30|NZ_CP045224|CRISPRCasFinder matches to NZ_CP012644 (Rufibacter tibetensis strain 1351 plasmid 1, complete sequence) position: , mismatch: 4, identity: 0.867

-ctatgtattttaaggctgttccatcttggt	CRISPR spacer
actttgt-ttttaagcctgttccttcttggt	Protospacer
 ** *** ******* ******* *******

327. spacer 1.6|337347|25|NZ_CP045224|CRT matches to CP011076 (Brevibacillus laterosporus strain B9 plasmid unnamed2, complete sequence) position: , mismatch: 5, identity: 0.8

agcaacagggacaaccggagcagat	CRISPR spacer
ggcaacaggggcaaccggagcaacc	Protospacer
.*********.***********. .

328. spacer 1.6|337347|25|NZ_CP045224|CRT matches to NZ_CP014284 (Bacillus thuringiensis strain Bt185 plasmid pBT1850294, complete sequence) position: , mismatch: 5, identity: 0.8

agcaacagggacaaccggagcagat	CRISPR spacer
tgcaacagggtcaaccggagcaacg	Protospacer
 ********* ***********.

329. spacer 1.6|337347|25|NZ_CP045224|CRT matches to NZ_CP032609 (Bacillus thuringiensis strain QZL38 plasmid p.2, complete sequence) position: , mismatch: 5, identity: 0.8

agcaacagggacaaccggagcagat	CRISPR spacer
tgcaacagggtcaaccggagcaacg	Protospacer
 ********* ***********.

330. spacer 2.11|455133|27|NZ_CP045224|CRT matches to MN480762 (Streptococcus salivarius strain NU10 plasmid pSsal-NU10, complete sequence) position: , mismatch: 5, identity: 0.815

gcaaccggagcaaatggtttggtaggt	CRISPR spacer
gttacgggagcaactggtttggtaggg	Protospacer
*. ** ******* ************

331. spacer 3.15|779897|39|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020425 (Clostridioides difficile strain FDAARGOS_267 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.872

agagacagtttaaaactaaatcagaagaaaagtcttata	CRISPR spacer
aaaagcaatttaaaactaaatcagaagaaaagtcatata	Protospacer
*.*..**.************************** ****

332. spacer 3.15|779897|39|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to FN668942 (Clostridium difficile BI1 plasmid pCDBI1, complete sequence) position: , mismatch: 5, identity: 0.872

agagacagtttaaaactaaatcagaagaaaagtcttata	CRISPR spacer
aaaagcaatttaaaactaaatcagaagaaaagtcatata	Protospacer
*.*..**.************************** ****

333. spacer 3.15|779897|39|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP011969 (Clostridioides difficile ATCC 9689 = DSM 1296 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.872

agagacagtttaaaactaaatcagaagaaaagtcttata	CRISPR spacer
aaaagcaatttaaaactaaatcagaagaaaagtcatata	Protospacer
*.*..**.************************** ****

334. spacer 7.3|1069105|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to HG531805 (Clostridium phage CDMH1 complete genome) position: , mismatch: 5, identity: 0.865

tggagaaggtcttggattagcaccaataggtcataga	CRISPR spacer
aggagaaggtcttggattagcaccaattggacacaaa	Protospacer
 ************************** ** **.*.*

335. spacer 7.24|1070491|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to JX145342 (Clostridium phage phiMMP04, complete genome) position: , mismatch: 5, identity: 0.861

gtcgtaaaacttaaagatgaaacaaaaggaatgatt	CRISPR spacer
gctataaaattaaaagatgaaacaaaaggaatgatt	Protospacer
*...*****.* ************************

336. spacer 10.1|2318788|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to MK473382 (Clostridium phage JD032, complete genome) position: , mismatch: 5, identity: 0.861

attcgcaagttcttaatcaaaaacccaattttcttt	CRISPR spacer
attagcaagttcttcatcaaaaacccaattgccctt	Protospacer
*** ********** *************** .*.**

337. spacer 2.9|455034|27|NZ_CP045224|CRT matches to NZ_CP023312 (Vibrio anguillarum strain VIB12 isolate Sea bass plasmid p292, complete sequence) position: , mismatch: 6, identity: 0.778

gcaacaggtccagatggagtaataggt	CRISPR spacer
gcaacagtcccagatggagtaattaag	Protospacer
******* .************** ..

338. spacer 2.15|455313|36|NZ_CP045224|CRT matches to CP011076 (Brevibacillus laterosporus strain B9 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.833

gcagtaggagcaaccggagcaacgggagtagcaggt	CRISPR spacer
gcaaccggagcaaccggagcaactggaggagcagga	Protospacer
***.. ***************** **** ******

339. spacer 3.8|779437|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020425 (Clostridioides difficile strain FDAARGOS_267 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.838

cgcatttttgcttttatattgcttcttctatcttcta	CRISPR spacer
ctcatctttgcttttatattgcttcttctagtatcga	Protospacer
* ***.************************ . ** *

340. spacer 3.8|779437|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to FN668942 (Clostridium difficile BI1 plasmid pCDBI1, complete sequence) position: , mismatch: 6, identity: 0.838

cgcatttttgcttttatattgcttcttctatcttcta	CRISPR spacer
ctcatctttgcttttatattgcttcttctagtatcga	Protospacer
* ***.************************ . ** *

341. spacer 3.8|779437|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP011969 (Clostridioides difficile ATCC 9689 = DSM 1296 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.838

cgcatttttgcttttatattgcttcttctatcttcta	CRISPR spacer
ctcatctttgcttttatattgcttcttctagtatcga	Protospacer
* ***.************************ . ** *

342. spacer 3.24|780486|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to MK473382 (Clostridium phage JD032, complete genome) position: , mismatch: 6, identity: 0.833

ctagtaaattttgctaaaaggcactattattgtagt	CRISPR spacer
gaggcaaattttgttaaaaggtactattattgtagt	Protospacer
  .*.********.*******.**************

343. spacer 7.14|1069830|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to MK473382 (Clostridium phage JD032, complete genome) position: , mismatch: 6, identity: 0.838

tcattataaccccaaccaactacagttgcagggattt	CRISPR spacer
gaaccataaccccaaccaagcacagttgcagggattt	Protospacer
  *..************** .****************

344. spacer 13.3|3182395|30|NZ_CP045224|CRISPRCasFinder matches to NZ_CP040675 (Exiguobacterium mexicanum strain A-EM plasmid punnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

tcactctt-----gccaatccaaattcactatttc	CRISPR spacer
-----cttagtgagccaatctaaattcactatttc	Protospacer
     ***     *******.**************

345. spacer 14.1|3936194|28|NZ_CP045224|CRISPRCasFinder matches to KY971610 (Pseudomonas phage PspYZU05, complete genome) position: , mismatch: 6, identity: 0.786

gttgattcatattgctttaacttattac	CRISPR spacer
gatgattcgtattgctgtaacttatcgt	Protospacer
* ******.******* ********...

346. spacer 2.9|455034|27|NZ_CP045224|CRT matches to AP014366 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S41-C63, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 7, identity: 0.741

gcaacaggtccagatggagtaataggt	CRISPR spacer
tactcaggtccagatggattaatagca	Protospacer
    ************** ******

347. spacer 7.43|1071744|37|NZ_CP045224|CRISPRCasFinder,CRT matches to NZ_CP013206 (Paenibacillus sp. IHB B 3084 plasmid pHD03, complete sequence) position: , mismatch: 7, identity: 0.811

-tgaagttttcttttaaattatcatcctgtatagcctt	CRISPR spacer
atgaaa-attcatttaaatcatcatcctgtatagctct	Protospacer
 ****.  *** *******.***************..*

348. spacer 8.10|1793685|35|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to MN855865 (Myoviridae sp. isolate 346, complete genome) position: , mismatch: 7, identity: 0.8

attttataatggtaaaaaagagttttacatagctg-	CRISPR spacer
atttgataatggtaaaaaagcgtttt-tattattgc	Protospacer
**** *************** ***** .** ..**

349. spacer 12.2|2802409|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP043618 (Sulfurimonas sp. GYSZ_1 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.811

aagataaaagtgaaatatctgaatatatagaaaaact	CRISPR spacer
caaataaaagtgaaatatatgaatatataaaaacttt	Protospacer
 *.*************** **********.***  .*

350. spacer 12.2|2802409|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP043618 (Sulfurimonas sp. GYSZ_1 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.811

aagataaaagtgaaatatctgaatatatagaaaaact	CRISPR spacer
caaataaaagtgaaatatatgaatatataaaaacttt	Protospacer
 *.*************** **********.***  .*

351. spacer 13.4|3182461|30|NZ_CP045224|CRISPRCasFinder matches to HM452126 (Aeromonas phage phiAS5, complete genome) position: , mismatch: 7, identity: 0.767

ttacatactccaaagcagtaccattttttt	CRISPR spacer
tcgcatactccaaagcagaacgatttgaat	Protospacer
*..*************** ** ****   *

352. spacer 13.7|3182659|30|NZ_CP045224|CRISPRCasFinder matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 7, identity: 0.767

gaacacattttattgcattgcaattttgtc	CRISPR spacer
taacacattttattgcattacaattagtag	Protospacer
 ******************.*****

353. spacer 13.8|3182725|30|NZ_CP045224|CRISPRCasFinder matches to NZ_CP015323 (Bacillus filamentosus strain Hbe603 plasmid pBEH1, complete sequence) position: , mismatch: 7, identity: 0.767

ttatgtatattaaattcaatccattttttc	CRISPR spacer
gtttagacattaaattcaatctatttttta	Protospacer
 * *. *.*************.*******

354. spacer 13.8|3182725|30|NZ_CP045224|CRISPRCasFinder matches to NC_025171 (Acinetobacter sp. M131 plasmid pM131-5, complete sequence) position: , mismatch: 7, identity: 0.767

ttatgtatattaaattcaatccattttttc	CRISPR spacer
cattttttattaaattcactctattttttc	Protospacer
.  * * *********** **.********

355. spacer 2.10|455079|36|NZ_CP045224|CRT matches to CP011076 (Brevibacillus laterosporus strain B9 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.778

gcaaccggagcaactggagcaaatggtttggtaggc	CRISPR spacer
gcaaccggagcaaccggagcaactggaggagcagga	Protospacer
**************.******* ***   .*.***

356. spacer 2.10|455079|36|NZ_CP045224|CRT matches to KF437907 (Phormidium phage MIS-PhV1A, complete genome) position: , mismatch: 8, identity: 0.778

gcaaccggagcaactggagcaaatggtttggtaggc	CRISPR spacer
gcaactggagcaactggagcaactggagcgatcgga	Protospacer
*****.**************** ***  .*.* **

357. spacer 7.24|1070491|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_013944 (Staphylococcus simulans bv. staphylolyticus strain NRRL B-2628 plasmid pACK1, complete sequence) position: , mismatch: 8, identity: 0.778

gtcgtaaaac----ttaaagatgaaacaaaaggaatgatt	CRISPR spacer
----caaaatgtcattgaagatgaaacaataggaatgatt	Protospacer
    .****.    **.************ **********

358. spacer 7.24|1070491|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_013945 (Staphylococcus simulans bv. staphylolyticus strain NRRL B-2628 plasmid pACK3, complete sequence) position: , mismatch: 8, identity: 0.778

gtcgtaaaac----ttaaagatgaaacaaaaggaatgatt	CRISPR spacer
----caaaatgtcattgaagatgaaacaataggaatgatt	Protospacer
    .****.    **.************ **********

359. spacer 8.10|1793685|35|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to NC_017736 (Helicobacter cetorum MIT 99-5656 plasmid pHCD, complete sequence) position: , mismatch: 8, identity: 0.771

attttataatggtaaaaaagagttttacatagctg	CRISPR spacer
gttttttaatgctaaaaaagagttttttaatgcta	Protospacer
.**** ***** ************** .*  ***.

360. spacer 8.10|1793685|35|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to NC_017736 (Helicobacter cetorum MIT 99-5656 plasmid pHCD, complete sequence) position: , mismatch: 8, identity: 0.771

attttataatggtaaaaaagagttttacatagctg	CRISPR spacer
gttttttaatgctaaaaaagagttttttaatgcta	Protospacer
.**** ***** ************** .*  ***.

361. spacer 8.27|1794805|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to MH884511 (Exiguobacterium phage vB_EalM-132, complete genome) position: , mismatch: 8, identity: 0.778

ttttcttctagctcttttttcttagccattttacca	CRISPR spacer
atgtcttcttgctcttttttcctagccatctcagct	Protospacer
 * ****** ***********.*******.*.* *

362. spacer 8.37|1795462|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP007513 (Bacillus bombysepticus plasmid pBb, complete genome) position: , mismatch: 8, identity: 0.778

taaattattagttttaaaatttaaagggggaaaaaa------	CRISPR spacer
taaattaatatttttaaaatttaaag------aaaacttatt	Protospacer
******* ** ***************      ****

363. spacer 8.37|1795462|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to CP046512 (Bacillus cereus strain JHU plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.778

taaattattagttttaaaatttaaagggggaaaaaa------	CRISPR spacer
taaattaatatttttaaaatttaaag------aaaacttatt	Protospacer
******* ** ***************      ****

364. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to AP013453 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G17, isolate: uvMED-CGR-U-MedDCM-OCT-S28-C28) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
ttattttagataataaagaagaaacaaacttt	Protospacer
****************.* *****.*  .*

365. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NZ_CP025426 (Enterococcus faecium strain SC4 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
tttcccttgataataaggtaggaataatttat	Protospacer
** ...* *************.**** ****

366. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to LT603679 (Enterococcus faecium isolate Ef_DMG1500501 genome assembly, plasmid: 2) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
tttcccttgataataaggtaggaataatttat	Protospacer
** ...* *************.**** ****

367. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NZ_CP040369 (Enterococcus faecium strain VB3240 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
tttcccttgataataaggtaggaataatttat	Protospacer
** ...* *************.**** ****

368. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NZ_CP043485 (Enterococcus faecium strain DMEA02 plasmid pDMEA1, complete sequence) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
tttcccttgataataaggtaggaataatttat	Protospacer
** ...* *************.**** ****

369. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NZ_CP020485 (Enterococcus faecium strain CFSAN059070 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
tttcccttgataataaggtaggaataatttat	Protospacer
** ...* *************.**** ****

370. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NZ_CP013995 (Enterococcus faecium strain 6E6 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
tttcccttgataataaggtaggaataatttat	Protospacer
** ...* *************.**** ****

371. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NZ_CP027518 (Enterococcus faecium strain AUSMDU00004024 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
tttcccttgataataaggtaggaataatttat	Protospacer
** ...* *************.**** ****

372. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NZ_CP027498 (Enterococcus faecium strain AUSMDU00004167 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
tttcccttgataataaggtaggaataatttat	Protospacer
** ...* *************.**** ****

373. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NZ_CP027507 (Enterococcus faecium strain AUSMDU00004055 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
tttcccttgataataaggtaggaataatttat	Protospacer
** ...* *************.**** ****

374. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NZ_CP046076 (Enterococcus faecium strain VRE plasmid p5_03A17012, complete sequence) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
tttcccttgataataaggtaggaataatttat	Protospacer
** ...* *************.**** ****

375. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NZ_LR135236 (Enterococcus faecium isolate E7067 plasmid 2) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
tttcccttgataataaggtaggaataatttat	Protospacer
** ...* *************.**** ****

376. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NZ_CP019209 (Enterococcus faecium strain 2014-VREF-41 plasmid p41-1, complete sequence) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
tttcccttgataataaggtaggaataatttat	Protospacer
** ...* *************.**** ****

377. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NZ_LR135429 (Enterococcus faecium isolate E8927 plasmid 2) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
tttcccttgataataaggtaggaataatttat	Protospacer
** ...* *************.**** ****

378. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NZ_LR135476 (Enterococcus faecium isolate E8423 plasmid 2) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
tttcccttgataataaggtaggaataatttat	Protospacer
** ...* *************.**** ****

379. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NZ_LR135220 (Enterococcus faecium isolate E7040 plasmid 2) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
tttcccttgataataaggtaggaataatttat	Protospacer
** ...* *************.**** ****

380. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NZ_LR135358 (Enterococcus faecium isolate E7948 plasmid 2) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
tttcccttgataataaggtaggaataatttat	Protospacer
** ...* *************.**** ****

381. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NZ_LR135352 (Enterococcus faecium isolate E8014 plasmid 2) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
tttcccttgataataaggtaggaataatttat	Protospacer
** ...* *************.**** ****

382. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NZ_LR134106 (Enterococcus faecium isolate E6043 plasmid 2) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
tttcccttgataataaggtaggaataatttat	Protospacer
** ...* *************.**** ****

383. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NC_025146 (Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
taattttagataataaagtagatatctaaaat	Protospacer
* **************.***** ** *   *

384. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NZ_CP011829 (Enterococcus faecium strain UW8175 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
tttcccttgataataaggtaggaataatttat	Protospacer
** ...* *************.**** ****

385. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NZ_CP045013 (Enterococcus faecium strain LAC7.2 plasmid pI, complete sequence) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
tttcccttgataataaggtaggaataatttat	Protospacer
** ...* *************.**** ****

386. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NC_012654 (Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
taattttagataataaagtagatatctaaaat	Protospacer
* **************.***** ** *   *

387. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NZ_CP025687 (Enterococcus faecium strain CBA7134 plasmid pCBA710401, complete sequence) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
tttcccttgataataaggtaggaataatttat	Protospacer
** ...* *************.**** ****

388. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NZ_CP040741 (Enterococcus faecium strain VRE1 plasmid pVRE1-1, complete sequence) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
tttcccttgataataaggtaggaataatttat	Protospacer
** ...* *************.**** ****

389. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NZ_CP040877 (Enterococcus faecium strain HB-1 plasmid punnamed, complete sequence) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
tttcccttgataataaggtaggaataatttat	Protospacer
** ...* *************.**** ****

390. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NZ_CP032307 (Enterococcus faecium strain HY07 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
tttcccttgataataaggtaggaataatttat	Protospacer
** ...* *************.**** ****

391. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NZ_CP031095 (Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
taattttagataataaagtagatatctaaaat	Protospacer
* **************.***** ** *   *

392. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NZ_CP019993 (Enterococcus faecium isolate 2014-VREF-268 plasmid p268-1, complete sequence) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
tttcccttgataataaggtaggaataatttat	Protospacer
** ...* *************.**** ****

393. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NZ_CP035655 (Enterococcus faecium strain UAMSEF_08 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
tttcccttgataataaggtaggaataatttat	Protospacer
** ...* *************.**** ****

394. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NZ_CP035137 (Enterococcus faecium strain SRCM103341 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
tttcccttgataataaggtaggaataatttat	Protospacer
** ...* *************.**** ****

395. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NZ_CP035661 (Enterococcus faecium strain UAMSEF_09 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
tttcccttgataataaggtaggaataatttat	Protospacer
** ...* *************.**** ****

396. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NZ_CP035667 (Enterococcus faecium strain UAMSEF_20 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
tttcccttgataataaggtaggaataatttat	Protospacer
** ...* *************.**** ****

397. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NZ_CP035649 (Enterococcus faecium strain UAMSEF_01 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
tttcccttgataataaggtaggaataatttat	Protospacer
** ...* *************.**** ****

398. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NZ_CP035221 (Enterococcus faecium strain SRCM103470 plasmid unnamed1) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
tttcccttgataataaggtaggaataatttat	Protospacer
** ...* *************.**** ****

399. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to LR135186 (Enterococcus faecium isolate E4413 genome assembly, plasmid: 2) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
tttcccttgataataaggtaggaataatttat	Protospacer
** ...* *************.**** ****

400. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NZ_CP042833 (Enterococcus faecium strain FA3 plasmid unnamed1) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
tttcccttgataataaggtaggaataatttat	Protospacer
** ...* *************.**** ****

401. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NZ_MG674581 (Enterococcus faecium strain HL1 plasmid pHLSA, complete sequence) position: , mismatch: 8, identity: 0.75

ttattttagataataaggtagaaatattttag	CRISPR spacer
tttcccttgataataaggtaggaataatttat	Protospacer
** ...* *************.**** ****

402. spacer 12.2|2802409|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_041928 (Staphylococcus phage phiIBB-SEP1, complete genome) position: , mismatch: 8, identity: 0.784

aagataaaagtgaaatatctgaatatatagaaaaact	CRISPR spacer
aaactaaaagagaaatatctgattatataggtcaagt	Protospacer
**. ****** *********** *******.  ** *

403. spacer 12.2|2802409|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to KP027447 (Staphylococcus phage phiIPLA-C1C, complete genome) position: , mismatch: 8, identity: 0.784

aagataaaagtgaaatatctgaatatatagaaaaact	CRISPR spacer
aaactaaaagagaaatatctgattatataggtcaagt	Protospacer
**. ****** *********** *******.  ** *

404. spacer 12.2|2802409|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to MH321490 (Staphylococcus phage Quidividi, complete genome) position: , mismatch: 8, identity: 0.784

aagataaaagtgaaatatctgaatatatagaaaaact	CRISPR spacer
aaactaaaagagaaatatctgattatataggtcaagt	Protospacer
**. ****** *********** *******.  ** *

405. spacer 12.2|2802409|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to MF417868 (Uncultured Caudovirales phage clone 7AX_1, partial genome) position: , mismatch: 8, identity: 0.784

aagataaaagtgaaatatctgaatatatagaaaaact	CRISPR spacer
aaactaaaagagaaatatctgattatataggtcaagt	Protospacer
**. ****** *********** *******.  ** *

406. spacer 13.7|3182659|30|NZ_CP045224|CRISPRCasFinder matches to NC_014663 (Acinetobacter phage Acj9, complete genome) position: , mismatch: 8, identity: 0.733

gaacacattttattgcattgcaattttgtc	CRISPR spacer
aaacaaattttgttgcattgcaatgacaac	Protospacer
.**** *****.************  .. *

407. spacer 1.3|337197|34|NZ_CP045224|CRT matches to MT375529 (Pelagibacter phage Kolga EXVC01, complete genome) position: , mismatch: 9, identity: 0.735

attaataggcccaaccggagcaacaggaacacct	CRISPR spacer
cccaataggcccaacaggtgcaacaggcccagca	Protospacer
 ..************ ** ********  ** *

408. spacer 1.3|337197|34|NZ_CP045224|CRT matches to NZ_CP012101 (Bacillus thuringiensis strain HS18-1 plasmid pHS18-2, complete sequence) position: , mismatch: 9, identity: 0.735

attaataggcccaaccggagcaacaggaacacct	CRISPR spacer
aggaataggcccaaccgggccaacagggcccggt	Protospacer
*  ***************. *******. *   *

409. spacer 1.5|337293|34|NZ_CP045224|CRT matches to MG945433 (UNVERIFIED: Microviridae sp. isolate 4854-1711, complete genome) position: , mismatch: 9, identity: 0.735

tccaaccggagcaaccggagcagatggagcaaca	CRISPR spacer
agtagacggagcaacaggagcagaaggagcagaa	Protospacer
  .*. ********* ******** ******. *

410. spacer 7.38|1071413|38|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to MG065657 (UNVERIFIED: Campylobacter phage C4, complete genome) position: , mismatch: 9, identity: 0.763

atattcatatactacatattcttttccttcatcattaa	CRISPR spacer
aatttgacgatctacatattcttcaccttcatcattaa	Protospacer
*  ** *..  ************. *************

411. spacer 7.38|1071413|38|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to MG065649 (UNVERIFIED: Campylobacter phage A143, complete genome) position: , mismatch: 9, identity: 0.763

atattcatatactacatattcttttccttcatcattaa	CRISPR spacer
aatttgacgatctacatattcttcaccttcatcattaa	Protospacer
*  ** *..  ************. *************

412. spacer 7.38|1071413|38|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to KC710998 (Shigella phage pSf-1, complete genome) position: , mismatch: 9, identity: 0.763

atattcatatactacatattcttttccttcatcattaa	CRISPR spacer
aatttgacgatctacatattcttcaccttcatcattaa	Protospacer
*  ** *..  ************. *************

413. spacer 7.38|1071413|38|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_049821 (Salmonella phage slyngel, complete genome) position: , mismatch: 9, identity: 0.763

atattcatatactacatattcttttccttcatcattaa	CRISPR spacer
aatttgacgatctacatattcttcaccttcatcattaa	Protospacer
*  ** *..  ************. *************

414. spacer 7.38|1071413|38|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to MK373798 (Escherichia phage vB_EcoS_G29-2, complete genome) position: , mismatch: 9, identity: 0.763

atattcatatactacatattcttttccttcatcattaa	CRISPR spacer
aatttgacgatctacatattcttcaccttcatcattaa	Protospacer
*  ** *..  ************. *************

415. spacer 7.38|1071413|38|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to MG065681 (UNVERIFIED: Campylobacter phage A139, complete genome) position: , mismatch: 9, identity: 0.763

atattcatatactacatattcttttccttcatcattaa	CRISPR spacer
aatttgacgatctacatattcttcaccttcatcattaa	Protospacer
*  ** *..  ************. *************

416. spacer 7.38|1071413|38|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to MG065680 (UNVERIFIED: Campylobacter phage A113, complete genome) position: , mismatch: 9, identity: 0.763

atattcatatactacatattcttttccttcatcattaa	CRISPR spacer
aatttgacgatctacatattcttcaccttcatcattaa	Protospacer
*  ** *..  ************. *************

417. spacer 7.38|1071413|38|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to MG065643 (UNVERIFIED: Campylobacter phage E6, complete genome) position: , mismatch: 9, identity: 0.763

atattcatatactacatattcttttccttcatcattaa	CRISPR spacer
aatttgacgatctacatattcttcaccttcatcattaa	Protospacer
*  ** *..  ************. *************

418. spacer 8.15|1794013|34|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to NC_015851 (Acidithiobacillus caldus SM-1 megaplasmid, complete sequence) position: , mismatch: 9, identity: 0.735

tcaaatctaactgatgttcttttattatcaaaag	CRISPR spacer
acaaatctaactgaaggtcttttattggacgaat	Protospacer
 ************* * *********.   .**

419. spacer 8.15|1794013|34|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP005987 (Acidithiobacillus caldus ATCC 51756 plasmid megap mpAca1.1, complete sequence) position: , mismatch: 9, identity: 0.735

tcaaatctaactgatgttcttttattatcaaaag	CRISPR spacer
acaaatctaactgaaggtcttttattggacgaat	Protospacer
 ************* * *********.   .**

420. spacer 8.15|1794013|34|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP026329 (Acidithiobacillus caldus strain MTH-04 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.735

tcaaatctaactgatgttcttttattatcaaaag	CRISPR spacer
acaaatctaactgaaggtcttttattggacgaat	Protospacer
 ************* * *********.   .**

421. spacer 8.35|1795331|35|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to MT774406 (CrAssphage cr124_1, complete genome) position: , mismatch: 9, identity: 0.743

tctatgttatgtacatgattaccttgtttgagtag	CRISPR spacer
aggatattatgtacatgattagcttgttaaagatg	Protospacer
   **.*************** ****** .**  *

422. spacer 10.12|2319514|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR215006 (Mycoplasma conjunctivae strain NCTC10147 plasmid 10) position: , mismatch: 9, identity: 0.757

tgaaaaattaaaagaattaatagataagcaattaata	CRISPR spacer
tgaaaaattaaatgaattaatagttaaaataaaatca	Protospacer
************ ********** ***.  *  * .*

423. spacer 10.12|2319514|37|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to LR214957 (Mycoplasma fermentans strain NCTC10117 genome assembly, plasmid: 3) position: , mismatch: 9, identity: 0.757

tgaaaaattaaaagaattaatagataagcaattaata	CRISPR spacer
tgaaaaattaaatgaattaatagttaaaataaaatca	Protospacer
************ ********** ***.  *  * .*

424. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NZ_LR214939 (Mycoplasma salivarium strain NCTC10113 plasmid 2) position: , mismatch: 9, identity: 0.719

ttattttagataataaggtagaaatattttag	CRISPR spacer
atgataataataattaggtagaaatgttttag	Protospacer
 *. *   .***** **********.******

425. spacer 11.1|2466602|32|NZ_CP045224|CRISPRCasFinder matches to NC_019763 (Oscillatoria nigro-viridis PCC 7112 plasmid pOSC7112.01, complete sequence) position: , mismatch: 9, identity: 0.719

ttattttagataataaggtagaaatattttag	CRISPR spacer
cttcgtgagataataacttagaaatattttca	Protospacer
.* . * *********  ************ .

426. spacer 1.3|337197|34|NZ_CP045224|CRT matches to NZ_CP020744 (Bacillus mycoides strain Gnyt1 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.706

attaataggcccaaccggagcaacaggaacacct	CRISPR spacer
agaaataggtccaacgggagcaacaggtctgaca	Protospacer
*  ******.***** ***********  .. *

427. spacer 1.3|337197|34|NZ_CP045224|CRT matches to NZ_CP020744 (Bacillus mycoides strain Gnyt1 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.706

attaataggcccaaccggagcaacaggaacacct	CRISPR spacer
agaaataggtccaacgggagcaacaggtctgaca	Protospacer
*  ******.***** ***********  .. *

428. spacer 1.3|337197|34|NZ_CP045224|CRT matches to NZ_CP020744 (Bacillus mycoides strain Gnyt1 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.706

attaataggcccaaccggagcaacaggaacacct	CRISPR spacer
agaaataggtccaacgggagcaacaggtctgaca	Protospacer
*  ******.***** ***********  .. *

429. spacer 1.5|337293|34|NZ_CP045224|CRT matches to NZ_CP028489 (Yersinia massiliensis strain GTA plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.706

tccaaccggagcaaccggagcagatggagcaaca	CRISPR spacer
tcgcgataatgcaaccggcgcagatggggcaaca	Protospacer
**  . ... ******** ********.******

430. spacer 1.5|337293|34|NZ_CP045224|CRT matches to MG945309 (UNVERIFIED: Microviridae sp. isolate 786-1711, complete genome) position: , mismatch: 10, identity: 0.706

tccaaccggagcaaccggagcagatggagcaaca	CRISPR spacer
agtagagggagcaacaggagcagaaggagcagaa	Protospacer
  .*.  ******** ******** ******. *

431. spacer 1.5|337293|34|NZ_CP045224|CRT matches to NC_009704 (Yersinia pseudotuberculosis IP 31758 plasmid p_59kb, complete sequence) position: , mismatch: 10, identity: 0.706

tccaaccggagcaaccggagcagatggagcaaca	CRISPR spacer
tcgcgataatgcaaccggcgcagatggggcaaca	Protospacer
**  . ... ******** ********.******

432. spacer 2.10|455079|36|NZ_CP045224|CRT matches to MN693862 (Marine virus AFVG_250M91, complete genome) position: , mismatch: 10, identity: 0.722

gcaaccggagcaactggagcaaatggtttggtaggc	CRISPR spacer
gcaaccggtgcaactggagcaactggcgcaactggt	Protospacer
******** ************* ***. .... **.

433. spacer 2.10|455079|36|NZ_CP045224|CRT matches to MN694690 (Marine virus AFVG_250M90, complete genome) position: , mismatch: 10, identity: 0.722

gcaaccggagcaactggagcaaatggtttggtaggc	CRISPR spacer
gcaaccggtgcaactggagcaactggcgcaactggt	Protospacer
******** ************* ***. .... **.

434. spacer 2.10|455079|36|NZ_CP045224|CRT matches to MN693992 (Marine virus AFVG_250M87, complete genome) position: , mismatch: 10, identity: 0.722

gcaaccggagcaactggagcaaatggtttggtaggc	CRISPR spacer
gcaaccggtgcaactggagcaactggcgcaactggt	Protospacer
******** ************* ***. .... **.

435. spacer 2.10|455079|36|NZ_CP045224|CRT matches to KF437907 (Phormidium phage MIS-PhV1A, complete genome) position: , mismatch: 10, identity: 0.722

gcaaccggagcaactggagcaaatggtttggtaggc	CRISPR spacer
gcaactggagcaactggagcaactggagcaactgga	Protospacer
*****.**************** ***  .... **

436. spacer 2.10|455079|36|NZ_CP045224|CRT matches to KF437907 (Phormidium phage MIS-PhV1A, complete genome) position: , mismatch: 10, identity: 0.722

gcaaccggagcaactggagcaaatggtttggtaggc	CRISPR spacer
gcaactggagcaactggagcaactggagcaactgga	Protospacer
*****.**************** ***  .... **

437. spacer 2.10|455079|36|NZ_CP045224|CRT matches to MN694247 (Marine virus AFVG_250M89, complete genome) position: , mismatch: 10, identity: 0.722

gcaaccggagcaactggagcaaatggtttggtaggc	CRISPR spacer
gcaaccggtgcaactggagcaactggcgcaactggt	Protospacer
******** ************* ***. .... **.

438. spacer 2.10|455079|36|NZ_CP045224|CRT matches to MN693850 (Marine virus AFVG_250M88, complete genome) position: , mismatch: 10, identity: 0.722

gcaaccggagcaactggagcaaatggtttggtaggc	CRISPR spacer
gcaaccggtgcaactggagcaactggcgcaactggt	Protospacer
******** ************* ***. .... **.

439. spacer 3.2|779049|35|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to MN033866 (Leviviridae sp. isolate H1_Bulk_Litter_6_scaffold_308 hypothetical protein (H1BulkLitter6308_000001), hypothetical protein (H1BulkLitter6308_000002), RNA-dependent RNA polymerase (H1BulkLitter6308_000003), and hypothetical protein (H1BulkLitter6308_000004) genes, complete cds) position: , mismatch: 10, identity: 0.714

attctttatacagagaaacacgatactatttacag	CRISPR spacer
taaagcgatacagagaaacacgatactctgtacgg	Protospacer
     . ******************** * ***.*

440. spacer 7.19|1070163|35|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP003988 (Streptomyces sp. 769 plasmid pSGZL, complete sequence) position: , mismatch: 10, identity: 0.714

atatgacagcacaaggaacacctacagcacaagca	CRISPR spacer
cggggacagcacaaggcccacctacagcacgtgtt	Protospacer
  . ************  ************. *.

441. spacer 8.10|1793685|35|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP034172 (Chryseobacterium taklimakanense strain H4753 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.714

attttataatggtaaaaaagagttttacatagctg	CRISPR spacer
tttttataatgttaaaaaagatttttcttttatta	Protospacer
 ********** ********* **** . * ..*.

442. spacer 8.22|1794474|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP050647 (Escherichia coli strain PapM-36-2 plasmid pIncFIB, complete sequence) position: , mismatch: 10, identity: 0.722

acacttattttgattttatttattttaattttttat	CRISPR spacer
gtgataaagatgattttattttttttaatcttttat	Protospacer
... * *   *********** *******.******

443. spacer 8.22|1794474|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to NC_019348 (Lactococcus lactis subsp. cremoris plasmid pAF07, complete sequence) position: , mismatch: 10, identity: 0.722

acacttattttgattttatttattttaattttttat	CRISPR spacer
acgaaatttttgatttgctttattttaatttttgcg	Protospacer
**.    *********  ***************

444. spacer 8.22|1794474|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to MN693542 (Marine virus AFVG_25M165, complete genome) position: , mismatch: 10, identity: 0.722

acacttattttgattttatttattttaattttttat	CRISPR spacer
ctttatattttgattttattttttctaatttatgaa	Protospacer
 . . **************** **.****** * *

445. spacer 8.22|1794474|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to MN693056 (Marine virus AFVG_25M10, complete genome) position: , mismatch: 11, identity: 0.694

acacttattttgattttatttattttaattttttat	CRISPR spacer
ctttatattttgattttattttttctaatttatgca	Protospacer
 . . **************** **.****** *

446. spacer 8.22|1794474|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to MN693152 (Marine virus AFVG_25M11, complete genome) position: , mismatch: 11, identity: 0.694

acacttattttgattttatttattttaattttttat	CRISPR spacer
ctttatattttgattttattttttctaatttatgca	Protospacer
 . . **************** **.****** *

447. spacer 8.22|1794474|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to MN693342 (Marine virus AFVG_25M9, complete genome) position: , mismatch: 11, identity: 0.694

acacttattttgattttatttattttaattttttat	CRISPR spacer
ctttatattttgattttattttttctaatttatgca	Protospacer
 . . **************** **.****** *

448. spacer 8.22|1794474|36|NZ_CP045224|CRT,CRISPRCasFinder,PILER-CR matches to MN693020 (Marine virus AFVG_117M64, complete genome) position: , mismatch: 11, identity: 0.694

acacttattttgattttatttattttaattttttat	CRISPR spacer
ctttatattttgattttattttttctaatttatgca	Protospacer
 . . **************** **.****** *

449. spacer 10.17|2319843|36|NZ_CP045224|PILER-CR,CRISPRCasFinder,CRT matches to NC_014389 (Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence) position: , mismatch: 11, identity: 0.694

aatctgtttttcttcttcttctgcattatctacaag	CRISPR spacer
ctcctgtttttcttcttcttcggtattataattgat	Protospacer
  .****************** *.*****   ..*

450. spacer 7.44|1071810|37|NZ_CP045224|CRISPRCasFinder,CRT matches to HG796590 (Uncultured bacterium plasmid pRGI01759) position: , mismatch: 12, identity: 0.676

atacaggaacaggagtcggaacagaaaaaaacgcctc	CRISPR spacer
gggttggaacaggggttggaacagaaaaaaagctttt	Protospacer
. .. ********.**.**************  ..*.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

954315 : 963267

Catovirus(50.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009906099.1\|954315_955155_+	glycosyltransferase family 2 protein	A0A2P1ELT8	Moumouvirus	1.8e-05	25.9
WP_022615338.1\|955169_956345_+	CDP-glycerol glycerophosphotransferase family protein	NA	NA	NA	NA
WP_003422862.1\|956373_957123_+	glycosyltransferase family 2 protein	A0A1V0SAH6	Catovirus	1.2e-16	38.8
WP_003422864.1\|957144_958053_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_003422866.1\|958100_958853_+	glycosyltransferase family 2 protein	A0A1V0SAH6	Catovirus	3.5e-16	40.5
WP_170324422.1\|958830_960174_+	nucleotide sugar dehydrogenase	A0A127AXI2	Bacillus_phage	1.1e-89	43.4
WP_003422869.1\|960179_961271_+	glycosyltransferase	A0A1V0SL50	Klosneuvirus	1.0e-16	26.2
WP_009906096.1\|961353_963267_+	polysaccharide biosynthesis protein	A0A1V0SAI8	Catovirus	1.1e-26	29.8

DBSCAN-SWA_2

1126777 : 1144299

Streptococcus_phage(100.0%)

integrase

attL 1125692:1125708|attR 1148011:1148027

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1125692:1125708	attL	NA	NA	NA	NA
WP_000420682.1\|1126777_1127092_+	YdcP family protein	A0A1S5SF38	Streptococcus_phage	5.2e-54	100.0
WP_000985015.1\|1127107_1127494_+	YdcP family protein	A0A1S5SF96	Streptococcus_phage	3.0e-64	100.0
WP_000813488.1\|1127522_1128908_+	DNA translocase FtsK	A0A1S5SFB5	Streptococcus_phage	1.1e-265	100.0
WP_000879507.1\|1128910_1129063_+	hypothetical protein	NA	NA	NA	NA
WP_000398284.1\|1129085_1130291_+	replication initiation factor domain-containing protein	A0A1S5SEX3	Streptococcus_phage	2.8e-233	100.0
WP_001009056.1\|1130333_1130555_+	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.3e-31	100.0
WP_000342539.1\|1130671_1131169_+	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	1.7e-91	100.0
WP_000506270.1\|1131143_1131650_+	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	8.6e-91	100.0
WP_000804748.1\|1134082_1136260_+	membrane protein	A0A1S5SF30	Streptococcus_phage	0.0e+00	100.0
WP_000769868.1\|1136256_1137258_+	lysozyme family protein	A0A1S5SEZ8	Streptococcus_phage	5.0e-191	100.0
WP_001224319.1\|1137254_1138187_+	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	1.1e-171	100.0
WP_001791010.1\|1138431_1138548_+	tetracycline resistance determinant leader peptide	NA	NA	NA	NA
WP_000691727.1\|1138563_1140483_+	tetracycline resistance ribosomal protection protein Tet(M)	A0A1S5SF82	Streptococcus_phage	0.0e+00	100.0
WP_000336323.1\|1140601_1140769_+	cysteine-rich KTR domain-containing protein	D0R0F6	Streptococcus_phage	1.6e-14	68.0
WP_001227347.1\|1140828_1141182_-	helix-turn-helix domain-containing protein	A0A1S5SFA6	Streptococcus_phage	1.3e-58	100.0
WP_000804885.1\|1141686_1142109_+	sigma-70 family RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	2.5e-72	100.0
WP_000857133.1\|1142105_1142336_+	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	2.7e-36	100.0
WP_000814511.1\|1142796_1143000_+	excisionase	A0A1S5SF07	Streptococcus_phage	4.0e-31	100.0
WP_001291561.1\|1143081_1144299_+\|integrase	tyrosine-type recombinase/integrase	A0A1S5SEW7	Streptococcus_phage	3.7e-233	100.0
1148011:1148027	attR	NA	NA	NA	NA

DBSCAN-SWA_3

1938110 : 1959461

Streptococcus_phage(94.74%)

integrase

attL 1926685:1926699|attR 1959686:1959700

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1926685:1926699	attL	NA	NA	NA	NA
WP_000420682.1\|1938110_1938425_+	YdcP family protein	A0A1S5SF38	Streptococcus_phage	5.2e-54	100.0
WP_000985015.1\|1938440_1938827_+	YdcP family protein	A0A1S5SF96	Streptococcus_phage	3.0e-64	100.0
WP_000813488.1\|1938855_1940241_+	DNA translocase FtsK	A0A1S5SFB5	Streptococcus_phage	1.1e-265	100.0
WP_000879507.1\|1940243_1940396_+	hypothetical protein	NA	NA	NA	NA
WP_000398284.1\|1940418_1941624_+	replication initiation factor domain-containing protein	A0A1S5SEX3	Streptococcus_phage	2.8e-233	100.0
WP_001009056.1\|1941666_1941888_+	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.3e-31	100.0
WP_000506270.1\|1942475_1942982_+	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	8.6e-91	100.0
WP_000331160.1\|1942965_1945413_+	ATP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	100.0
WP_000804748.1\|1945415_1947593_+	membrane protein	A0A1S5SF30	Streptococcus_phage	0.0e+00	100.0
WP_000769868.1\|1947589_1948591_+	lysozyme family protein	A0A1S5SEZ8	Streptococcus_phage	5.0e-191	100.0
WP_001224319.1\|1948587_1949520_+	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	1.1e-171	100.0
WP_001791010.1\|1949764_1949881_+	tetracycline resistance determinant leader peptide	NA	NA	NA	NA
WP_000691727.1\|1949896_1951816_+	tetracycline resistance ribosomal protection protein Tet(M)	A0A1S5SF82	Streptococcus_phage	0.0e+00	100.0
WP_000336323.1\|1951934_1952102_+	cysteine-rich KTR domain-containing protein	D0R0F6	Streptococcus_phage	1.6e-14	68.0
WP_001227347.1\|1952161_1952515_-	helix-turn-helix domain-containing protein	A0A1S5SFA6	Streptococcus_phage	1.3e-58	100.0
WP_000804885.1\|1953019_1953442_+	sigma-70 family RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	2.5e-72	100.0
WP_000857133.1\|1953438_1953669_+	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	2.7e-36	100.0
WP_000814511.1\|1954129_1954333_+	excisionase	A0A1S5SF07	Streptococcus_phage	4.0e-31	100.0
WP_001291561.1\|1954414_1955632_+\|integrase	tyrosine-type recombinase/integrase	A0A1S5SEW7	Streptococcus_phage	3.7e-233	100.0
WP_009905633.1\|1955906_1956464_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_003424097.1\|1956704_1957565_-	YitT family protein	M1Q1P6	Streptococcus_phage	1.3e-35	32.8
WP_003424094.1\|1958063_1959461_+	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	2.0e-20	27.2
1959686:1959700	attR	NA	NA	NA	NA

DBSCAN-SWA_4

2559326 : 2569055

Pandoravirus(37.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003419891.1\|2559326_2560493_-	RNA polymerase sigma factor RpoD	M4SMP8	Cyanophage	9.6e-37	36.8
WP_009905444.1\|2560510_2562301_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	1.2e-51	32.6
WP_003419887.1\|2562555_2563341_-	3-deoxy-7-phosphoheptulonate synthase	E3T537	Cafeteria_roenbergensis_virus	1.7e-13	27.9
WP_003419886.1\|2563321_2563828_-	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	S4VNV0	Pandoravirus	4.2e-13	33.9
WP_022615216.1\|2563820_2564186_-	dihydroneopterin aldolase	NA	NA	NA	NA
WP_003419883.1\|2564196_2564988_-	dihydropteroate synthase	A0A0B5J4J5	Pandoravirus	1.1e-23	30.0
WP_003419881.1\|2565053_2565626_-	GTP cyclohydrolase I FolE	E7DN69	Pneumococcus_phage	2.3e-44	51.6
WP_003419879.1\|2565651_2566353_-	hypothetical protein	NA	NA	NA	NA
WP_003419877.1\|2566386_2567130_-	aminotransferase class IV	NA	NA	NA	NA
WP_003419875.1\|2567119_2568469_-	aminodeoxychorismate synthase component I	S4VNU7	Pandoravirus	7.7e-38	41.6
WP_003419873.1\|2568470_2569055_-	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	2.5e-57	53.2

DBSCAN-SWA_5

2597782 : 2671888

Clostridium_phage(46.43%)

tail,integrase,portal,plate

attL 2592489:2592507|attR 2644184:2644202

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2592489:2592507	attL	NA	NA	NA	NA
WP_003419836.1\|2597782_2598127_+\|integrase	tyrosine-type recombinase/integrase	A0A090EUH1	Clostridium_phage	2.6e-30	69.1
WP_003419835.1\|2598317_2599673_+	MATE family efflux transporter	NA	NA	NA	NA
WP_003419834.1\|2599790_2600459_-	diphthine--ammonia ligase	NA	NA	NA	NA
WP_003419833.1\|2600525_2600954_-	DMT family transporter	NA	NA	NA	NA
WP_003419829.1\|2601065_2601659_+	DUF308 domain-containing protein	NA	NA	NA	NA
WP_009905437.1\|2601778_2602714_+	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	9.1e-46	62.3
WP_003419824.1\|2603015_2603960_-	EamA family transporter	NA	NA	NA	NA
WP_003419821.1\|2604277_2605720_+	sigma 54-interacting transcriptional regulator	NA	NA	NA	NA
WP_003419819.1\|2605919_2606504_+	zinc dependent phospholipase C family protein	NA	NA	NA	NA
WP_003419804.1\|2606597_2607377_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_003419802.1\|2607434_2608691_-	competence/damage-inducible protein A	B5TK85	Pseudomonas_phage	5.5e-14	34.0
WP_003419800.1\|2608948_2609848_+	D-alanine--D-alanine ligase	NA	NA	NA	NA
WP_003419798.1\|2609871_2611320_+	PLP-dependent aminotransferase family protein	NA	NA	NA	NA
WP_003419795.1\|2611378_2612185_+	M15 family metallopeptidase	NA	NA	NA	NA
WP_003419773.1\|2616263_2616611_-	PqqD family protein	NA	NA	NA	NA
WP_009905432.1\|2616597_2618529_-	oligopeptide transporter, OPT family	NA	NA	NA	NA
WP_003419766.1\|2618939_2621129_-	amino acid adenylation domain-containing protein	A0A2K9KZV5	Tupanvirus	4.4e-59	32.1
WP_003419763.1\|2621462_2622194_+	glycerophosphodiester phosphodiesterase	M1HTS7	Paramecium_bursaria_Chlorella_virus	1.0e-23	33.8
WP_003419760.1\|2622273_2622909_+	cysteine hydrolase	NA	NA	NA	NA
WP_003419758.1\|2623160_2623754_-	DUF3867 domain-containing protein	NA	NA	NA	NA
WP_003419753.1\|2623824_2624688_-	LD-carboxypeptidase	NA	NA	NA	NA
WP_003419751.1\|2624850_2626020_+	amidohydrolase	NA	NA	NA	NA
WP_003419749.1\|2626120_2626597_+	SAM-dependent methyltransferase	NA	NA	NA	NA
WP_022615211.1\|2627162_2627957_+	M55 family metallopeptidase	NA	NA	NA	NA
WP_003424678.1\|2627980_2628424_+	membrane protein	NA	NA	NA	NA
WP_003419735.1\|2628512_2629799_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_003419730.1\|2630016_2630907_-	DMT family transporter	NA	NA	NA	NA
WP_003419725.1\|2631198_2631543_+	RidA family protein	NA	NA	NA	NA
WP_003419722.1\|2631703_2633800_-	CocE/NonD family hydrolase	NA	NA	NA	NA
WP_003419720.1\|2633812_2634973_-	DUF819 family protein	NA	NA	NA	NA
WP_003419717.1\|2634991_2636059_-	dipeptide epimerase	Q6A202	Oenococcus_phage	3.1e-18	27.9
WP_003419715.1\|2636409_2636976_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003419711.1\|2637193_2638180_-	biotin-dependent carboxyltransferase	NA	NA	NA	NA
WP_009905429.1\|2638209_2638905_-	5-oxoprolinase subunit PxpB	NA	NA	NA	NA
WP_003419704.1\|2638924_2640145_-	divalent metal cation transporter	NA	NA	NA	NA
WP_003419698.1\|2640173_2640965_-	LamB/YcsF family protein	NA	NA	NA	NA
WP_003419696.1\|2641551_2642181_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_009905427.1\|2642291_2643806_-	glycerol kinase GlpK	NA	NA	NA	NA
WP_003419690.1\|2644049_2644592_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
2644184:2644202	attR	NA	NA	NA	NA
WP_003419688.1\|2644593_2647098_+	MFS transporter	NA	NA	NA	NA
WP_003419686.1\|2647515_2647914_+	helix-turn-helix domain-containing protein	A0A059T669	Listeria_phage	1.0e-06	34.5
WP_009905424.1\|2648130_2648340_-	hypothetical protein	NA	NA	NA	NA
WP_003419680.1\|2648371_2648581_-	helix-turn-helix transcriptional regulator	Q5YAA3	Bacillus_phage	5.9e-06	47.2
WP_003419677.1\|2648876_2649296_+	helix-turn-helix transcriptional regulator	S5MUV6	Brevibacillus_phage	1.6e-05	35.9
WP_003419674.1\|2649523_2649979_+	hypothetical protein	NA	NA	NA	NA
WP_003419670.1\|2650189_2650450_-	hypothetical protein	E2ELK7	Clostridium_phage	9.9e-35	90.6
WP_003419667.1\|2650712_2651066_-	hypothetical protein	A0A0A8WJF2	Clostridium_phage	5.5e-12	42.1
WP_003419666.1\|2651082_2656260_-	chromosome condensation regulator	A0A0A8WEY5	Clostridium_phage	2.6e-81	27.2
WP_003419664.1\|2656281_2657268_-\|tail	phage tail protein	A0A2H4J039	uncultured_Caudovirales_phage	7.6e-59	45.8
WP_003419661.1\|2657268_2657967_-	DUF2313 domain-containing protein	A0A090D815	Clostridium_phage	9.5e-48	56.9
WP_003419658.1\|2657963_2659016_-\|plate	baseplate J/gp47 family protein	A0A0A8WFP3	Clostridium_phage	3.5e-139	70.4
WP_003419656.1\|2659008_2659437_-	DUF2634 domain-containing protein	A0A0A8WJ32	Clostridium_phage	3.7e-63	81.0
WP_003419655.1\|2659436_2659763_-	DUF2577 domain-containing protein	J9QE86	Clostridium_phage	3.9e-52	92.6
WP_003419653.1\|2659778_2661308_-	C40 family peptidase	A0A1V0DZX6	Clostridioides_phage	1.3e-243	81.1
WP_003419651.1\|2661589_2662012_-	hypothetical protein	A0A090DBR9	Clostridium_phage	1.7e-52	71.1
WP_003419649.1\|2662011_2664465_-	hypothetical protein	A0A1V0DZX3	Clostridioides_phage	1.4e-16	58.4
WP_003419647.1\|2664658_2665105_-\|portal	phage portal protein	A0A090EUD0	Clostridium_phage	8.2e-13	36.0
WP_003419646.1\|2665218_2665647_-\|tail	phage tail tube protein	A0A1V0DZX1	Clostridioides_phage	2.8e-34	51.8
WP_003419645.1\|2665660_2666725_-\|tail	phage tail sheath subtilisin-like domain-containing protein	A0A1V0DZX4	Clostridioides_phage	5.8e-97	53.1
WP_003419644.1\|2666729_2667173_-	hypothetical protein	A0A1V0DZX9	Clostridioides_phage	2.0e-19	36.7
WP_003419643.1\|2667421_2667862_-	hypothetical protein	A0A090EUN5	Clostridium_phage	1.1e-28	47.9
WP_003419641.1\|2667965_2668163_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003419639.1\|2668331_2668652_+	XRE family transcriptional regulator	A0A0A8WE28	Clostridium_phage	9.7e-24	55.5
WP_003419636.1\|2668733_2669240_+	hypothetical protein	A0A0A8WEK1	Clostridium_phage	1.1e-56	67.7
WP_009889131.1\|2669940_2670696_+	peptidylprolyl isomerase	NA	NA	NA	NA
WP_009889129.1\|2670838_2671267_-	CBS domain-containing protein	NA	NA	NA	NA
WP_003419624.1\|2671687_2671888_-	cold-shock protein	A0A1W6JNX5	Morganella_phage	2.7e-16	66.2

DBSCAN-SWA_6

3385345 : 3455158

Streptococcus_phage(25.0%)

tRNA,protease,transposase,coat

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003418123.1\|3385345_3386443_-\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_003418119.1\|3386815_3386986_-	hypothetical protein	NA	NA	NA	NA
WP_003418116.1\|3387157_3387601_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_003418111.1\|3388314_3389205_-	radical SAM protein	NA	NA	NA	NA
WP_003418110.1\|3389584_3390382_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_003418109.1\|3390764_3391286_-	PadR family transcriptional regulator	NA	NA	NA	NA
WP_003418107.1\|3391816_3392494_+	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_003418106.1\|3393067_3393649_-	4Fe-4S binding protein	NA	NA	NA	NA
WP_003418105.1\|3393641_3393872_-	4Fe-4S binding protein	NA	NA	NA	NA
WP_003418102.1\|3394929_3395205_-	transcriptional regulator	NA	NA	NA	NA
WP_003418100.1\|3395280_3396582_-	AAA family ATPase	A0A218KST2	Xenohaliotis_phage	6.3e-21	29.3
WP_009904996.1\|3397050_3398289_-	conserved phage C-terminal domain-containing protein	A0A1V0E018	Clostridioides_phage	3.8e-15	40.6
WP_003418096.1\|3398736_3398994_-	transcriptional regulator	NA	NA	NA	NA
WP_003418094.1\|3399572_3399794_+	DUF1659 domain-containing protein	NA	NA	NA	NA
WP_003418092.1\|3400118_3400358_+	DUF2922 domain-containing protein	NA	NA	NA	NA
WP_003418089.1\|3400362_3400512_+	YvrJ family protein	NA	NA	NA	NA
WP_003418088.1\|3400768_3401206_+	LytTR family transcriptional regulator DNA-binding domain-containing protein	NA	NA	NA	NA
WP_003418087.1\|3401459_3402353_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_003418086.1\|3402518_3403343_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_170324423.1\|3403438_3404047_+	TetR family transcriptional regulator	NA	NA	NA	NA
WP_003418084.1\|3404150_3404327_+	hypothetical protein	NA	NA	NA	NA
WP_003418082.1\|3404620_3405895_+	sensor histidine kinase	X5JAC0	Clostridium_phage	1.4e-12	23.9
WP_003418080.1\|3406231_3406801_-	GrpB family protein	NA	NA	NA	NA
WP_003418078.1\|3407171_3407777_+	urea carboxylase-associated family protein	NA	NA	NA	NA
WP_003418075.1\|3408465_3410040_-	ClC family H(+)/Cl(-) exchange transporter	NA	NA	NA	NA
WP_009904989.1\|3410200_3410737_-	GrpB family protein	NA	NA	NA	NA
WP_003418071.1\|3410810_3411224_-	DUF3795 domain-containing protein	NA	NA	NA	NA
WP_003418069.1\|3411687_3412473_+	hypothetical protein	NA	NA	NA	NA
WP_003418066.1\|3413026_3413560_-	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	5.9e-34	49.4
WP_003418064.1\|3413721_3414375_-	DNA-3-methyladenine glycosylase 2 family protein	NA	NA	NA	NA
WP_003418062.1\|3415166_3415739_-	manganese catalase family protein	NA	NA	NA	NA
WP_003418056.1\|3415802_3416066_-\|coat	spore coat protein CotJB	NA	NA	NA	NA
WP_003418053.1\|3416065_3416287_-\|coat	spore coat associated protein CotJA	NA	NA	NA	NA
WP_003418051.1\|3416784_3417321_-	ParB-like nuclease domain-containing protein	A0A220GKT8	Streptococcus_phage	2.1e-63	69.7
WP_003418050.1\|3417338_3418652_-	DUF3440 domain-containing protein	A0A220GKF8	Streptococcus_phage	3.3e-94	41.5
WP_003418048.1\|3418986_3419427_+	DUF3788 domain-containing protein	NA	NA	NA	NA
WP_009904984.1\|3419596_3419785_-	hypothetical protein	NA	NA	NA	NA
WP_003418041.1\|3420682_3425893_-	50S ribosome-binding GTPase	NA	NA	NA	NA
WP_003418039.1\|3425907_3428424_-	hypothetical protein	NA	NA	NA	NA
WP_003418037.1\|3428843_3429131_-	hypothetical protein	NA	NA	NA	NA
WP_003418035.1\|3429150_3429426_-	hypothetical protein	NA	NA	NA	NA
WP_003418032.1\|3430552_3431734_+	GGDEF domain-containing protein	G3MA91	Bacillus_virus	6.6e-09	26.0
WP_029158113.1\|3432083_3432965_+	GGDEF domain-containing protein	NA	NA	NA	NA
WP_003418025.1\|3433012_3435097_+	EAL domain-containing protein	G3MA91	Bacillus_virus	2.9e-07	26.6
WP_009904978.1\|3435356_3437924_-	pyruvate, phosphate dikinase	A0A1V0SGR7	Hokovirus	3.5e-47	39.2
WP_003418018.1\|3437926_3438532_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_003418016.1\|3438900_3440361_-	NADP-dependent glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_003418014.1\|3440661_3441240_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_003418012.1\|3441290_3441524_+	hypothetical protein	NA	NA	NA	NA
WP_003421731.1\|3441532_3442783_+	MFS transporter	NA	NA	NA	NA
WP_009902004.1\|3442943_3443513_+	hydrolase	NA	NA	NA	NA
WP_003418006.1\|3443854_3445195_-	sensor histidine kinase	X5JAC0	Clostridium_phage	1.4e-79	39.7
WP_003418003.1\|3445554_3445752_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003418000.1\|3446099_3447191_-\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_009904969.1\|3447915_3449835_-\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	1.8e-144	39.9
WP_003417996.1\|3450627_3451230_-	DUF445 family protein	NA	NA	NA	NA
WP_003417993.1\|3451408_3452227_-	putative sporulation protein YtxC	NA	NA	NA	NA
WP_003417991.1\|3452229_3452991_-	hypothetical protein	NA	NA	NA	NA
WP_041160395.1\|3454039_3455158_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A0H3UZC2	Geobacillus_virus	1.4e-109	52.7

DBSCAN-SWA_7

3535655 : 3570590

Streptococcus_phage(81.48%)

integrase

attL 3528781:3528796|attR 3565605:3565620

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3528781:3528796	attL	NA	NA	NA	NA
WP_003417815.1\|3535655_3536846_-\|integrase	site-specific integrase	A0A1S5SEW7	Streptococcus_phage	3.1e-155	67.0
WP_002347229.1\|3536924_3537128_-	excisionase	A0A1S5SF07	Streptococcus_phage	1.9e-25	82.1
WP_009896525.1\|3537503_3537743_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_009896527.1\|3537735_3538164_-	hypothetical protein	A0A1S5SEW0	Streptococcus_phage	1.9e-22	43.1
WP_003417802.1\|3538444_3538669_-	hypothetical protein	NA	NA	NA	NA
WP_003417799.1\|3538795_3540529_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	7.1e-44	29.7
WP_003417796.1\|3540578_3542129_+	recombinase family protein	A0A2K5B2B2	Erysipelothrix_phage	8.6e-158	55.4
WP_000510187.1\|3542129_3542543_+	hypothetical protein	NA	NA	NA	NA
WP_003417792.1\|3542546_3544118_+	recombinase family protein	A0A2K5B2B4	Erysipelothrix_phage	1.1e-173	61.1
WP_000228166.1\|3544472_3545342_+	nucleotidyltransferase domain-containing protein	A0A1X9I6C9	Streptococcus_phage	4.3e-159	95.8
WP_000662263.1\|3545322_3546057_+	class I SAM-dependent methyltransferase	A0A1X9I6N4	Streptococcus_phage	1.5e-141	100.0
WP_001255864.1\|3546089_3546998_+	aminoglycoside nucleotidyltransferase ANT(6)-Ia	E4ZFP8	Streptococcus_phage	2.0e-167	93.4
WP_000627290.1\|3546994_3547537_+	streptothricin N-acetyltransferase Sat4	A0A1B0RXL7	Streptococcus_phage	8.9e-94	100.0
WP_001096887.1\|3547629_3548424_+	aminoglycoside O-phosphotransferase APH(3')-IIIa	E4ZFP6	Streptococcus_phage	2.3e-154	100.0
WP_001079938.1\|3548699_3549272_+	HTH domain-containing protein	A0A1B0RXM1	Streptococcus_phage	5.5e-102	99.5
WP_072387101.1\|3549244_3549652_+	WYL domain-containing protein	A0A1B0RXM3	Streptococcus_phage	1.1e-59	98.3
WP_000802831.1\|3549762_3550422_+	RibD family protein	A0A1B0RXM8	Streptococcus_phage	3.1e-125	100.0
WP_000582200.1\|3551083_3551335_+	hypothetical protein	NA	NA	NA	NA
WP_001277639.1\|3551453_3551825_+	hypothetical protein	NA	NA	NA	NA
WP_001085751.1\|3553255_3555073_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	4.8e-35	25.7
WP_003417631.1\|3555196_3556156_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000473997.1\|3556268_3557180_-	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	4.1e-83	52.1
WP_000768246.1\|3557196_3558204_-	lysozyme family protein	A0A1S5SEZ8	Streptococcus_phage	3.1e-132	68.8
WP_003417629.1\|3558200_3560411_-	hypothetical protein	A0A1S5SF30	Streptococcus_phage	1.6e-186	59.9
WP_003417628.1\|3560410_3562861_-	ATP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	76.1
WP_003061368.1\|3562838_3563237_-	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	4.1e-48	73.0
WP_003417623.1\|3563346_3563850_-	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	7.5e-55	60.8
WP_003417621.1\|3563867_3564371_-	antirestriction protein ArdA	NA	NA	NA	NA
WP_010774377.1\|3564289_3564586_-	hypothetical protein	NA	NA	NA	NA
WP_003417620.1\|3564686_3565160_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_002323342.1\|3565236_3565458_-	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	9.0e-29	87.7
WP_003417615.1\|3565458_3565593_-	DUF3789 domain-containing protein	NA	NA	NA	NA
WP_003417612.1\|3565604_3566801_-	XRE family transcriptional regulator	A0A1S5SEX3	Streptococcus_phage	4.3e-149	62.8
3565605:3565620	attR	NA	NA	NA	NA
WP_003417609.1\|3567045_3567462_-	hypothetical protein	NA	NA	NA	NA
WP_003417607.1\|3567465_3568848_-	cell division protein FtsK	A0A1S5SFB5	Streptococcus_phage	2.0e-174	66.7
WP_009274548.1\|3568948_3569275_-	hypothetical protein	NA	NA	NA	NA
WP_003417606.1\|3569290_3569698_-	helix-turn-helix domain-containing protein	A0A0A7AQV8	Bacillus_phage	2.6e-05	42.3
WP_003417604.1\|3569864_3570248_-	YdcP family protein	A0A1S5SF96	Streptococcus_phage	2.3e-32	55.9
WP_003417601.1\|3570263_3570590_-	YdcP family protein	A0A1S5SF38	Streptococcus_phage	2.0e-24	51.5

DBSCAN-SWA_8

3802273 : 3808977

Synechococcus_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003420974.1\|3802273_3803806_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	E3SNU8	Prochlorococcus_phage	2.3e-38	49.7
WP_003420972.1\|3803798_3804392_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	3.6e-24	39.9
WP_003420970.1\|3804385_3805462_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F760	Synechococcus_phage	2.9e-64	42.8
WP_003420968.1\|3805455_3806823_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.2e-49	31.0
WP_003420966.1\|3806834_3807533_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3F9V5	Synechococcus_phage	1.5e-45	43.9
WP_003420964.1\|3807538_3808015_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	3.1e-26	45.8
WP_003420963.1\|3808464_3808977_+	nitroreductase family protein	A0A1V0E011	Clostridioides_phage	1.7e-83	87.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP045224

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection