CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP045297	Paenibacillus brasilensis strain KACC 13842 plasmid unnamed1, complete sequence	0 crisprs	NA	0	0	0	0
NZ_CP045298	Paenibacillus brasilensis strain KACC 13842 chromosome, complete genome	13 crisprs	RT,csa3,WYL,cas14j,DinG,cas3,DEDDh,cas8b1,cas7b,cas5,cas4,cas1,cas2,cas8c,cas7	15	18	16	2

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP045298_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045298_1

1864862-1866385

Orphan

I-C

Consensus_repeat	Method
ATTTCAATCCACGCACTCATATAGAGTGCGAC	CRISPRCasFinder
ATTTCAATCCACGCACTCATATAGAGTGCGAC	CRT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	PILER-CR

22 spacers

The CRISPR arrays of NZ_CP045298_1

>merge|NZ_CP045298|1|1864862-1866385|CRISPRCasFinder,CRT,PILER-CR
TAGCAAATCCACGCACTCATACAGAGTGCGACACCGGTGTGTTGAGTTAGGGCGACTGGATTGTTTATTTCAATCCACGCACTCATATAGAGTGCGACAAGAATCCCGGAACAGTGCCCGGCGTAGTTGGATTGCGATTTCAATCCACGCACTCATATAGAGTGCGACGTCTAAAATATGACCCATTGGCAGATGATGAGTCATATTTCAATCCACGCACTCATATAGAGTGCGACAAATATGAACGTGAAATCGAAGTTGAGATTCCAGATATTTCAATCCACGCACTCATATAGAGTGCGACGGTCGACGGGGAGGTGCCCCGTGTGTTCATGTTCGAATTTCAATCCACGCACTCATATAGAGTGCGACTGTTACCTATTTCGGTCATCATTTCGCCCGCTACCCACTCATTTCAATCCACGCACTCATATAGAGTGCGACGTTAGAGTCCAAGAGAAAAACATCTCAAGAGTGGGCAATTTCAATCCACACACTCATATAGAGTGCGACTAAAGCCCGAGTTATCAACTGTAGCGCCTTGGAAATTTCAATCCACGCACTCATATAGAGTGCGACGGGAGGTATCGGTAAAAGAGGTTCGTCTGCGTGAAATATTTCAATCCACGCACTCATATAGAGTGCGACGGTCAAACACAAAGCCGCAGCGTGGGCATTTGCAATCATTTCAATCCACGCACTCATATAGAGTGCGACCAACTTTGCCTCTTTCTCTTCCAGGGTTCCTGGTAAATTTCAATCCACGCACTCATATAGAGTGCGACCTGGAAGATGAAGACCTGTATCCAGATGACGAAGTGATTTCAATCCACGCACTCATATAGAGTGCGACATGAAGCCCTGTATCGCCTTCTGGCCGATCTGGAGATTTCAATCCACGCACTCATATAGAGTGCGACGGTCCTGTTAACTTCACTCCTAACCAGTTCTTGAAATTTCAATCCACGCACTCATATAGAGTGCGACCTTGATGCCGTATTGGGCGGAGGTTGGCCAGCAGATTTCAATCCACGCACTCATATAGAGTGCGACGCATAGACCTGAAACGGTTGATCTACGCTCAGCCAATTTCAATCCACGCACTCATATAGAGTGCGACACCTCTTGAATGTCCTAATTAAAACCAAAAATGGATTTCAATCCACGCACTCATATAGAGTGCGACCTACGAAAATATAAGCGACTAAAGCAGTAGACAGTAAATTTCAATCCACGCACTCATATAGAGTGCGACTCCAAACGCTATACGGTCTTTGGTATCAAAGGAGCATTTCAATCCACGCACTCATATAGAGTGCGACTTTGCAATGGCTTTAGCCGTTTCCTTTTCATCAAATTTCAATCCACGCACTCATATAGAGTGCGACTTACCTGTTCCCGCAGCGTAGGCCACACCCCCCAGGAATTTCAATCCACGCACTCATATAGAGTGCGACCGATTCATCACGAAAGAGTAGACGACAATCAGAATATTTCAATCCACGCACTCATATAGAGTGCGAC

>NZ_CP045298|1|1|1864862-1866385|CRISPRCasFinder
TAGCAAATCCACGCACTCATACAGAGTGCGAC	ACCGGTGTGTTGAGTTAGGGCGACTGGATTGTTT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	AAGAATCCCGGAACAGTGCCCGGCGTAGTTGGATTGCG
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GTCTAAAATATGACCCATTGGCAGATGATGAGTCAT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	AAATATGAACGTGAAATCGAAGTTGAGATTCCAGAT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GGTCGACGGGGAGGTGCCCCGTGTGTTCATGTTCGA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TGTTACCTATTTCGGTCATCATTTCGCCCGCTACCCACTC
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GTTAGAGTCCAAGAGAAAAACATCTCAAGAGTGGGCA
ATTTCAATCCACACACTCATATAGAGTGCGAC	TAAAGCCCGAGTTATCAACTGTAGCGCCTTGGAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GGGAGGTATCGGTAAAAGAGGTTCGTCTGCGTGAAAT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GGTCAAACACAAAGCCGCAGCGTGGGCATTTGCAATC
ATTTCAATCCACGCACTCATATAGAGTGCGAC	CAACTTTGCCTCTTTCTCTTCCAGGGTTCCTGGTAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	CTGGAAGATGAAGACCTGTATCCAGATGACGAAGTG
ATTTCAATCCACGCACTCATATAGAGTGCGAC	ATGAAGCCCTGTATCGCCTTCTGGCCGATCTGGAG
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GGTCCTGTTAACTTCACTCCTAACCAGTTCTTGAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	CTTGATGCCGTATTGGGCGGAGGTTGGCCAGCAG
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GCATAGACCTGAAACGGTTGATCTACGCTCAGCCA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	ACCTCTTGAATGTCCTAATTAAAACCAAAAATGG
ATTTCAATCCACGCACTCATATAGAGTGCGAC	CTACGAAAATATAAGCGACTAAAGCAGTAGACAGTAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TCCAAACGCTATACGGTCTTTGGTATCAAAGGAGC
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TTTGCAATGGCTTTAGCCGTTTCCTTTTCATCAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TTACCTGTTCCCGCAGCGTAGGCCACACCCCCCAGGA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	CGATTCATCACGAAAGAGTAGACGACAATCAGAAT
ATTTCAATCCACGCACTCATATAGAGTGCGAC

>NZ_CP045298|1|1|1864862-1866385|CRT
TAGCAAATCCACGCACTCATACAGAGTGCGAC	ACCGGTGTGTTGAGTTAGGGCGACTGGATTGTTT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	AAGAATCCCGGAACAGTGCCCGGCGTAGTTGGATTGCG
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GTCTAAAATATGACCCATTGGCAGATGATGAGTCAT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	AAATATGAACGTGAAATCGAAGTTGAGATTCCAGAT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GGTCGACGGGGAGGTGCCCCGTGTGTTCATGTTCGA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TGTTACCTATTTCGGTCATCATTTCGCCCGCTACCCACTC
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GTTAGAGTCCAAGAGAAAAACATCTCAAGAGTGGGCA
ATTTCAATCCACACACTCATATAGAGTGCGAC	TAAAGCCCGAGTTATCAACTGTAGCGCCTTGGAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GGGAGGTATCGGTAAAAGAGGTTCGTCTGCGTGAAAT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GGTCAAACACAAAGCCGCAGCGTGGGCATTTGCAATC
ATTTCAATCCACGCACTCATATAGAGTGCGAC	CAACTTTGCCTCTTTCTCTTCCAGGGTTCCTGGTAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	CTGGAAGATGAAGACCTGTATCCAGATGACGAAGTG
ATTTCAATCCACGCACTCATATAGAGTGCGAC	ATGAAGCCCTGTATCGCCTTCTGGCCGATCTGGAG
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GGTCCTGTTAACTTCACTCCTAACCAGTTCTTGAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	CTTGATGCCGTATTGGGCGGAGGTTGGCCAGCAG
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GCATAGACCTGAAACGGTTGATCTACGCTCAGCCA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	ACCTCTTGAATGTCCTAATTAAAACCAAAAATGG
ATTTCAATCCACGCACTCATATAGAGTGCGAC	CTACGAAAATATAAGCGACTAAAGCAGTAGACAGTAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TCCAAACGCTATACGGTCTTTGGTATCAAAGGAGC
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TTTGCAATGGCTTTAGCCGTTTCCTTTTCATCAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TTACCTGTTCCCGCAGCGTAGGCCACACCCCCCAGGA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	CGATTCATCACGAAAGAGTAGACGACAATCAGAAT
ATTTCAATCCACGCACTCATATAGAGTGCGAC

>NZ_CP045298|1|1|1864928-1866385|PILER-CR
ATTTCAATCCACGCACTCATATAGAGTGCGAC	AAGAATCCCGGAACAGTGCCCGGCGTAGTTGGATTGCG
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GTCTAAAATATGACCCATTGGCAGATGATGAGTCAT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	AAATATGAACGTGAAATCGAAGTTGAGATTCCAGAT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GGTCGACGGGGAGGTGCCCCGTGTGTTCATGTTCGA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TGTTACCTATTTCGGTCATCATTTCGCCCGCTACCCACTC
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GTTAGAGTCCAAGAGAAAAACATCTCAAGAGTGGGCA
ATTTCAATCCACACACTCATATAGAGTGCGAC	TAAAGCCCGAGTTATCAACTGTAGCGCCTTGGAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GGGAGGTATCGGTAAAAGAGGTTCGTCTGCGTGAAAT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GGTCAAACACAAAGCCGCAGCGTGGGCATTTGCAATC
ATTTCAATCCACGCACTCATATAGAGTGCGAC	CAACTTTGCCTCTTTCTCTTCCAGGGTTCCTGGTAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	CTGGAAGATGAAGACCTGTATCCAGATGACGAAGTG
ATTTCAATCCACGCACTCATATAGAGTGCGAC	ATGAAGCCCTGTATCGCCTTCTGGCCGATCTGGAG
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GGTCCTGTTAACTTCACTCCTAACCAGTTCTTGAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	CTTGATGCCGTATTGGGCGGAGGTTGGCCAGCAG
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GCATAGACCTGAAACGGTTGATCTACGCTCAGCCA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	ACCTCTTGAATGTCCTAATTAAAACCAAAAATGG
ATTTCAATCCACGCACTCATATAGAGTGCGAC	CTACGAAAATATAAGCGACTAAAGCAGTAGACAGTAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TCCAAACGCTATACGGTCTTTGGTATCAAAGGAGC
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TTTGCAATGGCTTTAGCCGTTTCCTTTTCATCAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TTACCTGTTCCCGCAGCGTAGGCCACACCCCCCAGGA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	CGATTCATCACGAAAGAGTAGACGACAATCAGAAT
ATTTCAATCCACGCACTCATATAGAGTGCGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045298.1\|WP_167518666.1\|1868767_1869748_+\|EamA-family-transporter	unknown	unknown	gnl\|CDD\|307170
NZ_CP045298.1\|WP_152379741.1\|1860989_1862609_-\|spore-germination-protein	unknown	unknown	gnl\|CDD\|377020
NZ_CP045298.1\|WP_152379740.1\|1859769_1860990_-\|Ger(x)C-family-spore-germination-protein	unknown	unknown	gnl\|CDD\|274338
NZ_CP045298.1\|WP_025717775.1\|1867729_1868587_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176133
NZ_CP045298.1\|WP_152379750.1\|1874750_1875146_-\|transcriptional-repressor	unknown	unknown	gnl\|CDD\|133478
NZ_CP045298.1\|WP_152382126.1\|1854498_1856265_-\|precorrin-3B-C(17)-methyltransferase	unknown	unknown	gnl\|CDD\|381173
NZ_CP045298.1\|WP_152379736.1\|1853354_1854407_-\|sirohydrochlorin-chelatase	unknown	unknown	gnl\|CDD\|225049
NZ_CP045298.1\|WP_152379747.1\|1869840_1871826_-\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|223910
NZ_CP045298.1\|WP_152379739.1\|1859552_1859777_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045298.1\|WP_167518665.1\|1852260_1852425_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045298.1\|WP_152379749.1\|1873375_1873789_-\|BlaI/MecI/CopY-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|367747
NZ_CP045298.1\|WP_152379745.1\|1866945_1867659_-\|pirin-family-protein	unknown	unknown	gnl\|CDD\|380375
NZ_CP045298.1\|WP_152379735.1\|1852593_1853358_-\|precorrin-6A-reductase	unknown	unknown	gnl\|CDD\|376826
NZ_CP045298.1\|WP_025716630.1\|1871981_1872389_-\|DoxX-family-protein	unknown	unknown	gnl\|CDD\|225168
NZ_CP045298.1\|WP_152379738.1\|1857472_1858324_-\|uroporphyrinogen-III-synthase	unknown	unknown	gnl\|CDD\|235647
NZ_CP045298.1\|WP_025716633.1\|1873935_1874775_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_CP045298.1\|WP_152379737.1\|1856761_1857316_-\|TIGR00730-family-Rossman-fold-protein	unknown	unknown	gnl\|CDD\|129813
NZ_CP045298.1\|WP_152379742.1\|1863003_1864401_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|238045
NZ_CP045298.1\|WP_152379744.1\|1866594_1866930_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045298.1\|WP_152379748.1\|1872511_1873372_-\|M48-family-metalloprotease	unknown	unknown	gnl\|CDD\|320685

Protein	Function_ID	Function_description	E-value
NZ_CP045298.1\|WP_167518666.1\|1868767_1869748_+\|EamA-family-transporter	gnl\|CDD\|307170	pfam00892, EamA, EamA-like transporter family. This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region. The family used to be known as DUF6. Members of this family usually carry 5+5 transmembrane domains, and this domain attempts to model five of these.	3.42346e-10
NZ_CP045298.1\|WP_152379741.1\|1860989_1862609_-\|spore-germination-protein	gnl\|CDD\|377020	pfam03323, GerA, Bacillus/Clostridium GerA spore germination protein.	0
NZ_CP045298.1\|WP_152379740.1\|1859769_1860990_-\|Ger(x)C-family-spore-germination-protein	gnl\|CDD\|274338	TIGR02887, Spore_germination_protein_B3, germination protein, Ger(x)C family. Members of this protein family are restricted to endospore-forming members of the Firmicutes lineage of bacteria, including the genera Bacillus, Clostridium, Thermoanaerobacter, Carboxydothermus, etc. Members are nearly all predicted lipoproteins and belong to probable transport operons, some of which have been characterized as crucial to germination in response to alanine. Members typically have been gene symbols gerKC, gerAC, gerYC, etc. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Sporulation and germination].	5.04734e-87
NZ_CP045298.1\|WP_025717775.1\|1867729_1868587_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176133	cd08442, PBP2_YofA_SoxR_like, The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold. YofA is a LysR-like transcriptional regulator of cell growth in Bacillus subtillis. YofA controls cell viability and the formation of constrictions during cell division. YofaA positively regulates expression of the cell division gene ftsW, and thus is essential for cell viability during stationary-phase growth of Bacillus substilis. YofA shows significant homology to SoxR from Arthrobacter sp. TE1826. SoxR is a negative regulator for the sarcosine oxidase gene soxA. Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine, which is involved in the metabolism of creatine and choline. The topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.39928e-73
NZ_CP045298.1\|WP_152379750.1\|1874750_1875146_-\|transcriptional-repressor	gnl\|CDD\|133478	cd07153, Fur_like, Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators. Ferric uptake regulator (Fur) and related metalloregulatory proteins are iron-dependent, DNA-binding repressors and activators mainly involved in iron metabolism. A general model for Fur repression under iron-rich conditions is that activated Fur (a dimer having one Fe2+ coordinated per monomer) binds to specific DNA sequences (Fur boxes) in the promoter region of iron-responsive genes, hindering access of RNA polymerase, and repressing transcription. Positive regulation by Fur can be direct or indirect, as in the Fur repression of an anti-sense regulatory small RNA. Some members sense metal ions other than Fe2+. For example, the zinc uptake regulator (Zur) responds to Zn2+, the manganese uptake regulator (Mur) responds to Mn2+, and the nickel uptake regulator (Nur) responds to Ni2+. Other members sense signals other than metal ions. For example, PerR, a metal-dependent sensor of hydrogen peroxide. PerR regulates DNA-binding activity through metal-based protein oxidation, and co-ordinates Mn2+ or Fe2+ at its regulatory site. Fur family proteins contain an N-terminal winged-helix DNA-binding domain followed by a dimerization domain; this CD spans both those domains.	3.46313e-35
NZ_CP045298.1\|WP_152382126.1\|1854498_1856265_-\|precorrin-3B-C(17)-methyltransferase	gnl\|CDD\|381173	cd11646, Precorrin_3B_C17_MT, Precorrin-3B C(17)-methyltransferase (also named CobJ or CbiH). Precorrin-3B C(17)-methyltransferase participates in the pathway toward the biosynthesis of cobalamin (vitamin B12). There are two distinct cobalamin biosynthetic pathways. The aerobic pathway requires oxygen, and cobalt is inserted late in the pathway; the anaerobic pathway does not require oxygen, and cobalt insertion is the first committed step towards cobalamin synthesis. This model includes CobJ of the aerobic pathway and CbiH of the anaerobic pathway, both as stand-alone enzymes and when CobJ or CbiH form part of bifunctional enzymes, such as in Mycobacterium tuberculosis CobIJ where CobJ fuses with a precorrin-2 C(20)-methyltransferase domain, or Bacillus megaterium CbiH60, where CbiH is fused to a nitrite and sulfite reductase-like domain. In the aerobic pathway, once CobG has generated precorrin-3b, CobJ catalyzes the methylation of precorrin-3b at C-17 to form precorrin-4 (the extruded methylated C-20 fragment is left attached as an acyl group at C-1). In the corresponding anaerobic pathway, CbiH carries out this ring contraction, using cobalt-precorrin-3b as a substrate to generate a tetramethylated delta-lactone.	3.0491e-142
NZ_CP045298.1\|WP_152379736.1\|1853354_1854407_-\|sirohydrochlorin-chelatase	gnl\|CDD\|225049	COG2138, COG2138, Sirohydrochlorin ferrochelatase [Inorganic ion transport and metabolism].	1.45586e-54
NZ_CP045298.1\|WP_152379747.1\|1869840_1871826_-\|HAMP-domain-containing-protein	gnl\|CDD\|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	1.3945e-65
NZ_CP045298.1\|WP_025716633.1\|1873935_1874775_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	2.06587e-31
NZ_CP045298.1\|WP_152379738.1\|1857472_1858324_-\|uroporphyrinogen-III-synthase	gnl\|CDD\|235647	PRK05928, hemD, uroporphyrinogen-III synthase; Reviewed.	7.85067e-58
NZ_CP045298.1\|WP_152379745.1\|1866945_1867659_-\|pirin-family-protein	gnl\|CDD\|380375	cd02910, cupin_Yhhw_N, Escherichia coli YhhW and YhaK and related proteins, pirin-like bicupin, N-terminal cupin domain. This family includes the N-terminal cupin domains of YhhW and YhaK, Escherichia coli pirin-like proteins with unknown function. YhhW is structurally similar not only to human pirin but also to quercitin 2,3-dioxygenase (quercitinase). Although the function of YhhW is not completely understood, YhhW and its human ortholog have quercitinase activity and are likely to play an important role in transcription and apoptosis. This N-terminal cupin domain of YhhW has a metal coordination site and is thought to have catalytic activity while the C-terminal cupin-like domain has diverged considerably and has closer alignment with C-terminal pirin. YhaK is found in low abundance in the cytosol of E. coli and is strongly up-regulated by nitroso-glutathione (GSNO). There are major structural differences at the N-terminus of YhaK compared with YhhW; YhaK lacks the canonical cupin metal-binding residues of pirins and may be involved in chloride binding and/or sensing of oxidative stress in enterobacteria. YhaK showed no quercetinase and peroxidase activity; however, reduced YhaK was very sensitive to reactive oxygen species (ROS). Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold.	6.51488e-58
NZ_CP045298.1\|WP_152379735.1\|1852593_1853358_-\|precorrin-6A-reductase	gnl\|CDD\|376826	pfam02571, CbiJ, Precorrin-6x reductase CbiJ/CobK. This family consists of Precorrin-6x reductase EC:1.3.1.54. This enzyme catalyzes the reaction: precorrin-6Y + NADP(+) <=> precorrin-6X + NADPH. CbiJ and CobK both catalyze the reduction of macocycle in the colbalmin biosynthesis pathway.	5.27247e-106
NZ_CP045298.1\|WP_025716630.1\|1871981_1872389_-\|DoxX-family-protein	gnl\|CDD\|225168	COG2259, COG2259, Predicted membrane protein [Function unknown].	7.45536e-18
NZ_CP045298.1\|WP_152379737.1\|1856761_1857316_-\|TIGR00730-family-Rossman-fold-protein	gnl\|CDD\|129813	TIGR00730, LOG_family_protein_YJL055W, TIGR00730 family protein. This model represents one branch of a subfamily of proteins of unknown function. Both PSI-BLAST and weak hits by this model show a low level of similarity to and suggest an evolutionary relationship of the subfamily to the DprA/Smf family of DNA-processing proteins involved in chromosomal transformation with foreign DNA. Both Aquifex aeolicus and Mycobacterium leprae have one member in each of two branches of this subfamily, suggesting that the branches may have distinct functions. [Hypothetical proteins, Conserved].	4.96408e-62
NZ_CP045298.1\|WP_152379749.1\|1873375_1873789_-\|BlaI/MecI/CopY-family-transcriptional-regulator	gnl\|CDD\|367747	pfam03965, Penicillinase_R, Penicillinase repressor. The penicillinase repressor negatively regulates expression of the penicillinase gene. The N-terminal region of this protein is involved in operator recognition, while the C-terminal is responsible for dimerization of the protein.	3.8251e-26
NZ_CP045298.1\|WP_152379742.1\|1863003_1864401_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.0044e-07
NZ_CP045298.1\|WP_152379748.1\|1872511_1873372_-\|M48-family-metalloprotease	gnl\|CDD\|320685	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase. This family contains peptidase M56, which includes zinc metalloprotease domain in MecR1 as well as BlaR1. MecR1 is a transmembrane beta-lactam sensor/signal transducer protein that regulates the expression of an altered penicillin-binding protein PBP2a, which resists inactivation by beta-lactam antibiotics, in methicillin-resistant Staphylococcus aureus (MRSA). BlaR1 regulates the inducible expression of a class A beta-lactamase that hydrolytically destroys certain ?-lactam antibiotics in MRSA. Both, MecR1 and BlaR1, are transmembrane proteins that consist of four transmembrane helices, a cytoplasmic zinc protease domain, and the soluble C-terminal extracellular sensor domain, and are highly similar in sequence and function. The signal for protein expression is transmitted by site-specific proteolytic cleavage of both the transducer, which auto-activates, and the repressor, which is inactivated, unblocking gene transcription. All members contain the zinc metalloprotease motif (HEXXH). Homologs of this peptidase domain are also found in a number of other bacterial genome sequences, most of which are as yet uncharacterized.	5.91305e-49

>NZ_CP045298.1|WP_152379742.1|1863003_1864401_-|helix-turn-helix-domain-containing-protein
MKHTPMITTEFEAYLKQNNMTLAQFAEYSGVHQRTLSNWVTQRRSVSVQQLDRITKAMGLPEGYFYDLYIENYIIDLPPNMRRIEPLLYRCAELDRLDTIRRIVGHIMDNLLYSPRLFEIAETLFAQGRHAAALPLYENVADVEKYQHSERLATCQYRLFTIQIGEDQSRNLRVASVFEVFVERLDEIDQLDALKDLANVYRSMRKWDRLDETARKMKEKAKAQYTLRHQQKSRERGEAAKKLSRPMFVYITYADLLCASVCEAQGDYQQALQYTYAYANLDWVKETDEDTLHWIGLFQHWAEGNTYVYKLLSGNTSVLTDYVEFIAASTNKSDKEMVTKLLNVMLAANRYQIDVDNILRRFETEINFITQQQPSADMYTHQVVPEQSTRFKYELAKYYLNRGRYSIGFKYLLDVLSKSLAINKEAFFIRCIRLFEQFKEFADVQAHSNYETLVSKGKKYKLFYY
>NZ_CP045298.1|WP_152379741.1|1860989_1862609_-|spore-germination-protein
MRKGPKLPRLPWSRRAIPAADRKTQNTNALKGLPEPPWLEQPLRSSLEDNLTALRDIFKDCSDIVYRELMISPERKGLLAYVEGTVKSEDLQDHILRPFILGMMLKDPEVNGTLDPLDETRISMSQTKTMDQWKMVSAAILDGNAALFVDGKSRAYIFSAKGGVRRGVEEPQTEAVIRGPREGFTETLRVNTALLRFKLKTSRLKMHSMTIGTETQTSVVLAYIEGIIDPKLVEDVKKRLSDIKIDAVLETGYIEELIEDHPFSPFPQMEYTERPDTATAQLLEGRFAIFVDGTPFALIGPVTIWQMMQASEDYYERFFISNMVRWIRFLFLILALFLPALYVAVTTYHHDMLPTTLILSIAAARESIPFPALVEALMMEISFEALREAGIRLPKTVGQAVSILGALVIGQAAVQAGIVSAPIVIVVSLTGIASFTIPRFNFAITIRLLRFPIMLMAGVFGLFGIIIATTLIATHLTKLTSFGVPYMSGYSPYNHNDQKDIVVRAPWWKMIKRPSWIGNDNNKREKEKMNGSPTTEEGW
>NZ_CP045298.1|WP_152379740.1|1859769_1860990_-|Ger(x)C-family-spore-germination-protein
MKPKGSNAGKIRKAAMLSCLLLCSVLLGGCWDRREVNDVAFVMGTGLDKEGDQYRVTMQIALPGQLGSSGSTGGGGGTRGTKSYYLESKIGPSFRGASAEEQRGVSRTLNFSHRRVLLFGEALAREGISKMMDVLARIPQNRLSSLVVITKGTSLDVLQADAPIELYPAEMVRELNFSYMKKPRSIKLLMNSILMDGMDPAVPVMSLVKNGPATIKDKKTNIQVDGLAVFRKDRLTGMIDNHLSRFLLLGMGQAKDTEIFISPPKGSGYLSVRLIENTVQIKPYIRGNDIRMTVQLNCNGNVRENETTFDISHGENVKWLEQQAAQEIKKELGEVVRLIQQKYHSDALGLGRAIIMSRPDEWKRIKSQWEQLYPKVEVVIDPIVHIENIGAVTKPFGIKKEEIENE
>NZ_CP045298.1|WP_152379739.1|1859552_1859777_-|hypothetical-protein
MNKVFLFPLVLVMLLMYLIDRKSLNSAPAVNRWISRVLYVISIGIWLYGTSTKSSVYVATWLSRFIDLWLPPTL
>NZ_CP045298.1|WP_152379738.1|1857472_1858324_-|uroporphyrinogen-III-synthase
MAQRMAGKRVALAGPRKADEMALLVAKMGGEPVQRPAQGTVFLDDIELRNAVVAWVKHPPDWNIFTTGMGLNALFDMAEDMGVAEQIIELLQGSNIAARGYKTVNELKKRGFTPDVRDEDGSLDGLTRAFAPYDLKGKEVLLQLHGDPAPRLVKWLDEQGAVTRQVLPYKHIPPEEANLQALLADIVSRSVDAVTFTSGPQIRFLCQYAREQNRMEDLLEAFRQDVIAVSVGKVTAQSILEEGIERIVFPVEERMGAMMVELGKYFEHRGSAHGFGLEVVNGH
>NZ_CP045298.1|WP_152379737.1|1856761_1857316_-|TIGR00730-family-Rossman-fold-protein
MNSICVFAGSRPGHSSVYLEAAGKLGEAMARHHVRLIYGGSSRGLMGEVANGMLTGGGQVTGIMPTLLFDAEIVHRGVTEFIEVANMHERKAAMSEMADAFIALPGGLGTFEELFEVLCWAQIGIHRKPIGLLNVSGYFDPLVEMVRHSVQEGFTGSEHPSLLSISADPDELLRMLKNKAENLK
>NZ_CP045298.1|WP_152382126.1|1854498_1856265_-|precorrin-3B-C(17)-methyltransferase
MSPLGKLLVIGFGPGDMEHITKRALDALSESEVIIGYNTYVDLIRPLLNGQEIVRTGMTEEVSRAQEAVRQAEMGKKVAVISSGDAGVYGMAGLVYEVLMQKGWRREDGVEVEVVPGISAIQSCASLLGAPVMHDACTISLSDHLTPWETIVKRVEAAASADFVIALYNPRSGRRTRQIVETQSILLRYRDPQTPVGLVKSAYRERQQVIVTTLEDMLNHDIGMLTTVIIGNSSTMVYDGLIVTPRGYQRKYTLDATEQALKPHQRLRTEAEPWSLGAQAGAAPAVPGPSASVAATAVAAQARPQAVAAVQGSPSAAQAGSAPASLAAEALSRLAAGGRLPDDASARWSGQTPAVSASGVGAAAGTATGGFGKPALFEVGVSPGVGNKKFTARQMALLAEIAGEDGEVEYTPDHQIVLRVPCADPEELVGRLRDERLIVMPIGDVFKVKACDFCNMEKDDAVPVAEHLQVVLGGLQAPKETSIALNGCGMACYGAVLEDIGIVYRKGGYDLFLGGKKFGRNAHAAQPVAEGIPGEQITDIVEHIIAEYKEKGHPNERFHKFFKRVGVVAGFRHEDAPATVEVNAVCGD
>NZ_CP045298.1|WP_152379736.1|1853354_1854407_-|sirohydrochlorin-chelatase
MNAILLVGHGSRDPEGNEELLEFAQAVADRVPGTCVETCFLELTRPSIADGVQACVKRGATRVVLVPIILFAAGHAKIDIPMAIDRAKARHPQVEFVYGRPIGVHEKIVSILQSRLKEARPVAVPAGMNNAVEASAGVTDEETAVLVLGRGSSDPDANSDFFKMSRMLWEKLPYTWVESSFIGVTQPSFSDGLERCVRLGAKKIIVLPYFLFTGVLIKRIGEMTEEFAEAHPELQVEIGGYFGFHPQLVELVLERANEGLFGKVAANCDNCQFRLEAQEHHHHHHDHDHDHDHGHDHHHHHDHHGHHHEHDHAHAHSHNDHNHEHHHEHLHTPSVGDSSGIAGSGQVKNS
>NZ_CP045298.1|WP_152379735.1|1852593_1853358_-|precorrin-6A-reductase
MIFMLCGTSDARELALQIRDKGFRVLTSVVTESAAISLSEAGLDVRTGRMTADEMAAVVRELGVQAIVDASHPFAEEAHVNAMAAARESGVPYIRYERAGLVYDNHPLLHIVPSYEEAALEAKQLKGSVMLTTGSKTLGTFTRHLLGDPEIRLVARMLPRLDNMEKCSELGMEQKNIIAMQGPFSREMNEALYKHFGTTVMVTKESGRTGAVDEKVQSALELGIHVILISRPEVEFGTVFDHFDGVIDALRTAE
>NZ_CP045298.1|WP_167518665.1|1852260_1852425_-|hypothetical-protein
MNLKNEHKNGVVGMVLYKRSGRFCPRIPTLIIGFIQGIRGRWRWEAPSDCVVEQ
>NZ_CP045298.1|WP_152379744.1|1866594_1866930_-|hypothetical-protein
MAQQETWLIKHAVTGRSFADSRKQAFDCRLDTTDGLFRFTLQELPRETAETIVRYREELNVFRFVTPEEQSIVKHWYYVTPESVKYNDQTGELTLEAGSEIEYHPEEYWGD
>NZ_CP045298.1|WP_152379745.1|1866945_1867659_-|pirin-family-protein
MFTIYPAASRFSFDKGWLRGSHSFSFAEYQDENNTAFGPMRVCNDDVIAPGRGFGAHPHSDMEIVSIVLHGELRHEDNRGHVAVTRFGGIQRMSAGRGIIHTEHNASQTEDVSLLQLWFSPHTRGLEPSYEATAFNPERLHGQLLPVVAGKNAQGTEGEIAAIHQDLTIYLSKLQPGERVEFTQAEGRRVFLFIIEGSLRVNGEHILRGRDSARIEQEPKLSLEAQEPVFYMLIDLP
>NZ_CP045298.1|WP_025717775.1|1867729_1868587_-|LysR-family-transcriptional-regulator
MDLNDLNIFQTVAAHGSVSKAAAELSYVQSNVTARIKLLEKELQTPLFYRHKRGMILNAEGKRLLQYTKSILSQFEEMKHAFQSTSAPSGVLEIGIVETVVALPSILHAYYSHYPDVELSLKAGVTEHLVQEVAEMRLDGAFVTGPVKHPLIEQFDVFQEKLVLVSQGDDFSIEDITTRPLLLYKKGCGYRERLETWLKMEGIIPKQIMEFGTFETIVGSVAAGIGMTVFPESSISGLKAQGHVHCHALPEPYNEVTTVFIRRKEAYVTSTLQSFINEIIAQIQA
>NZ_CP045298.1|WP_167518666.1|1868767_1869748_+|EamA-family-transporter
MNRQIMTGSLLCLIASMSWGAMFPVSHIALQQVNPLYFSFLRYFSVTLILIVLLWLKEGRAAFRFEGKGKTLLFFGTMGFTIYNMAVFQGQHWMGAAGTIVASIMEVLMPMISIAMIWVMTRKMPPKYTLVSMVIALAGAVLVITNGKWTFFTLAGQHLLPLLLIFTGVVGWVVYSMGGSHFAGWSTLRYSTLTCLLGTLVSFVVVTVSSAFHWITVPGWQDVWSVKYEMSFMILLPGLAALLSWNAGIRMLSPLNGILFINFVPITTLVLMYFQGYTISQFELYGTLLVIFALVLNNMVQRGSLRTTSSPRRIRVRLDRPKSFQR
>NZ_CP045298.1|WP_152379747.1|1869840_1871826_-|HAMP-domain-containing-protein
MEETRKRKTIWTLRNKLILGFLLVLLLPSLSISIATYRSSYNAMEKQLHSSANQGVATANSIIEYAIASKIKDVKYLADRLDGAMIDGRNSPLIQPKLIQYKGLHEDANDIFVGTPEGLMIRGVPKENEGTYDPRKRDWYIEAMKQPGKVAITPVLINSSGIPVVVVSQTLSDQSGVIGISLNLESVRKLASIKVGQEGYIIILDHTKKFVVHPTAKPGSSLDASFINDMYAAPSGQYTYVYEGQEKYLNYVTNKDTGWKIAGTFYQSEISDATAAMRYVTIFVLAASLVIALIAIFLITRSVLIPIRNLQKSAEQISEGDLTGDLETGKTDEVGQLSSHFQTMVDSLRTMIRSVHETTDRVSTSAEELAAGADQTTKAIEHVTIAIQEVSVGSERQLQSVKHGSVSMEELAQQAASVSERMVGVSEQVKRNAESAQSGSKAATRAVQKMHDIDETVNDLGHAMDSLNERSGEIGNIISVISGIAKQTNLLALNASIEAARAGDHGKGFAVVATEVRKLAEESAKSATLISERIEAMQMDMDHALTAMQQARSRVTEGIDSVSTSEQSFAEISQAVERAMGHIDDITGVTQGMAHGAAGVVSIMSDISHISNEAAGNTESISAAAEQQLASIEEIASSSADLSQMAEELRELVGRFQIGEK
>NZ_CP045298.1|WP_025716630.1|1871981_1872389_-|DoxX-family-protein
MNQTLTNIGLLLVRIFTGVIFIVHGSQKFQGLDGTSGFFQSIGLPGWLAPVVATVELVGGIALVLGIGTRLAGAALTIVMIGVLLTAKKGQPFGSIEFDLLILFTSLQQALVGGRFLAVDQLFGRKKSESSNVQV
>NZ_CP045298.1|WP_152379748.1|1872511_1873372_-|M48-family-metalloprotease
MWKTRSKLLFTAGALISGFALIQMGMYAGQHIFGWELNFNVFQICRSLLQNYGIGYMVDALSGLVFLTFGIAGGEAIRQCMATRAAFRRLHRMRDLSLTEALGERYREIGAGRIWVIDYAKPAAFTMGLWKPRIVLSSALLSVLDKHEEEAVVYHEAYHMKHYDPLKTWLLQMCATLLFYLPVLRHITNHYKIAREILADNEAIHRTGSPMGIGSALLKLLSMKPANTRLVNSVACSSFAETSINYRISRILDPQQEPIIQMPWRSIMFSSYVLVMLTLMFALALM
>NZ_CP045298.1|WP_152379749.1|1873375_1873789_-|BlaI/MecI/CopY-family-transcriptional-regulator
MKRMNFKAGETGLNRFFGPLEAKIMDILWSTSDRSIKEVQTALEGDRDFNFNTVMTVMNRLVEKGILSKSIRGRTSLYRPVLSREEFMDEQSKELSHELVDEFGPLAVNHMIDALEVADPVLIERLEQKIKQWKKEM
>NZ_CP045298.1|WP_025716633.1|1873935_1874775_-|response-regulator-transcription-factor
MPKQANQVTNRFKADEMPTRVNGSWTTMLSDPSAPAFQTVPSNEPLYCPTTRRLVLISSVPGVVHGLVRTLSDACFDVMVFHRWEPEVQRHLGSDLLIYDLTATDTRSELLDFRNRLAAEHMKGIPVMYVVQDRLAVRAHELLPSEEVLVWPLVSNHMVHDIERMIVRHPAASRQAEQTSRRTVFKDIWIDRDKMLVYKEEKQLSLTKTEYDLLLKLIDAQGKVISREQMMHDIWETDFVGGSNVVDVHVKSLRKKLDDRPAEPEYIATVRGVGYRLAD
>NZ_CP045298.1|WP_152379750.1|1874750_1875146_-|transcriptional-repressor
MRTLNLTSQRQAVYDVVREAHDHPTAADVMNRLMERGYNLAYGTVYNSLRYLTDKELIRELKLGEAASRYDGRMDDHQHIICQVCGRVDEVMSEVPHDWIETVAHETGYNIAHAHVVFGGVCKECQSKRIK

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Crispr_ID: NZ_CP045298_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045298_2

2402063-2402156

Orphan

Consensus_repeat	Method
TCCATGCTGGATCTAAGATACAAGCAGAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045298_2

>merge|NZ_CP045298|2|2402063-2402156|CRISPRCasFinder
TCCATGCTGGATCTAAGATACAAGCAGAGAAATATACGAGATTTCCAGACGTTTGTCGATTTCGCTCCATGCTGGATCTAAGATACAAGCAGAG

>NZ_CP045298|2|2|2402063-2402156|CRISPRCasFinder
TCCATGCTGGATCTAAGATACAAGCAGAG	AAATATACGAGATTTCCAGACGTTTGTCGATTTCGC
TCCATGCTGGATCTAAGATACAAGCAGAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045298.1\|WP_152380054.1\|2364699_2365941_+\|beta-ketoacyl-ACP-synthase-II	unknown	unknown	gnl\|CDD\|274452
NZ_CP045298.1\|WP_025720931.1\|2404723_2405290_+\|pyridoxal-5'-phosphate-synthase-glutaminase-subunit-PdxT	unknown	unknown	gnl\|CDD\|237411
NZ_CP045298.1\|WP_007428073.1\|2407304_2407475_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045298.1\|WP_152380052.1\|2361755_2362979_+\|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|223944
NZ_CP045298.1\|WP_025720943.1\|2409730_2410231_-\|tRNA-adenosine(34)-deaminase-TadA	unknown	unknown	gnl\|CDD\|223663
NZ_CP045298.1\|WP_152380057.1\|2393487_2394522_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP045298.1\|WP_152380050.1\|2359413_2360184_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223696
NZ_CP045298.1\|WP_152380049.1\|2358123_2358651_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045298.1\|WP_152380053.1\|2362975_2364676_+\|thiamine-pyrophosphate-binding-protein	unknown	unknown	gnl\|CDD\|223107
NZ_CP045298.1\|WP_152380051.1\|2360196_2361657_+\|AMP-binding-protein	unknown	unknown	gnl\|CDD\|341228
NZ_CP045298.1\|WP_152380061.1\|2409087_2409651_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|224584
NZ_CP045298.1\|WP_152380058.1\|2402303_2403692_+\|D-alanyl-D-alanine-carboxypeptidase	unknown	unknown	gnl\|CDD\|224600
NZ_CP045298.1\|WP_152380059.1\|2405328_2406612_+\|serine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235461
NZ_CP045298.1\|WP_152380056.1\|2366423_2393378_+\|non-ribosomal-peptide-synthase/polyketide-synthase	unknown	unknown	gnl\|CDD\|237054
NZ_CP045298.1\|WP_025720938.1\|2407546_2407702_+\|small-acid-soluble-spore-protein-P	unknown	unknown	unknown
NZ_CP045298.1\|WP_025720936.1\|2406934_2407276_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045298.1\|WP_025720926.1\|2400455_2401913_+\|IMP-dehydrogenase	unknown	unknown	gnl\|CDD\|235507
NZ_CP045298.1\|WP_152380060.1\|2407900_2408977_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045298.1\|WP_025720930.1\|2403824_2404706_+\|pyridoxal-5'-phosphate-synthase-lyase-subunit-PdxS	unknown	unknown	gnl\|CDD\|179769
NZ_CP045298.1\|WP_152380055.1\|2365945_2366362_+\|beta-hydroxyacyl-ACP-dehydratase	unknown	unknown	gnl\|CDD\|238615

Protein	Function_ID	Function_description	E-value
NZ_CP045298.1\|WP_152380054.1\|2364699_2365941_+\|beta-ketoacyl-ACP-synthase-II	gnl\|CDD\|274452	TIGR03150, fabF, beta-ketoacyl-acyl-carrier-protein synthase II. 3-oxoacyl-[acyl-carrier-protein] synthase 2 (KAS-II, FabF) is involved in the condensation step of fatty acid biosynthesis in which the malonyl donor group is decarboxylated and the resulting carbanion used to attack and extend the acyl group attached to the acyl carrier protein. Most genomes encoding fatty acid biosynthesis contain a number of condensing enzymes, often of all three types: 1, 2 and 3. Synthase 2 is mechanistically related to synthase 1 (KAS-I, FabB) containing a number of absolutely conserved catalytic residues in common. This model is based primarily on genes which are found in apparent operons with other essential genes of fatty acid biosynthesis (GenProp0681). The large gap between the trusted cutoff and the noise cutoff contains many genes which are not found adjacent to genes of the fatty acid pathway in genomes that often also contain a better hit to this model. These genes may be involved in other processes such as polyketide biosyntheses. Some genomes contain more than one above-trusted hit to this model which may result from recent paralogous expansions. Second hits to this model which are not next to other fatty acid biosynthesis genes may be involved in other processes. FabB sequences should fall well below the noise cutoff of this model. [Fatty acid and phospholipid metabolism, Biosynthesis].	0
NZ_CP045298.1\|WP_025720931.1\|2404723_2405290_+\|pyridoxal-5'-phosphate-synthase-glutaminase-subunit-PdxT	gnl\|CDD\|237411	PRK13525, PRK13525, pyridoxal 5'-phosphate synthase glutaminase subunit PdxT.	9.70686e-121
NZ_CP045298.1\|WP_025720943.1\|2409730_2410231_-\|tRNA-adenosine(34)-deaminase-TadA	gnl\|CDD\|223663	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis].	2.51855e-75
NZ_CP045298.1\|WP_152380052.1\|2361755_2362979_+\|aldehyde-dehydrogenase-family-protein	gnl\|CDD\|223944	COG1012, PutA, NAD-dependent aldehyde dehydrogenases [Energy production and conversion].	2.2139e-28
NZ_CP045298.1\|WP_152380057.1\|2393487_2394522_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	6.13993e-19
NZ_CP045298.1\|WP_152380050.1\|2359413_2360184_+\|SDR-family-oxidoreductase	gnl\|CDD\|223696	COG0623, FabI, Enoyl-[acyl-carrier-protein].	1.63404e-137
NZ_CP045298.1\|WP_152380055.1\|2365945_2366362_+\|beta-hydroxyacyl-ACP-dehydratase	gnl\|CDD\|238615	cd01288, FabZ, FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid biosynthesis pathway.	1.18191e-33
NZ_CP045298.1\|WP_152380053.1\|2362975_2364676_+\|thiamine-pyrophosphate-binding-protein	gnl\|CDD\|223107	COG0028, IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] [Amino acid transport and metabolism / Coenzyme metabolism].	8.58542e-95
NZ_CP045298.1\|WP_152380051.1\|2360196_2361657_+\|AMP-binding-protein	gnl\|CDD\|341228	cd04433, AFD_class_I, Adenylate forming domain, Class I, also known as the ANL superfamily. This family is known as the ANL (acyl-CoA synthetases, the NRPS adenylation domains, and the Luciferase enzymes) superfamily. It includes acyl- and aryl-CoA ligases, as well as the adenylation domain of nonribosomal peptide synthetases and firefly luciferases.The adenylate-forming enzymes catalyze an ATP-dependent two-step reaction to first activate a carboxylate substrate as an adenylate and then transfer the carboxylate to the pantetheine group of either coenzyme A or an acyl-carrier protein. The active site of the domain is located at the interface of a large N-terminal subdomain and a smaller C-terminal subdomain.	5.18098e-66
NZ_CP045298.1\|WP_152380061.1\|2409087_2409651_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	2.77161e-34
NZ_CP045298.1\|WP_152380058.1\|2402303_2403692_+\|D-alanyl-D-alanine-carboxypeptidase	gnl\|CDD\|224600	COG1686, DacC, D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane].	5.13287e-111
NZ_CP045298.1\|WP_152380059.1\|2405328_2406612_+\|serine--tRNA-ligase	gnl\|CDD\|235461	PRK05431, PRK05431, seryl-tRNA synthetase; Provisional.	0
NZ_CP045298.1\|WP_152380056.1\|2366423_2393378_+\|non-ribosomal-peptide-synthase/polyketide-synthase	gnl\|CDD\|237054	PRK12316, PRK12316, peptide synthase; Provisional.	0
NZ_CP045298.1\|WP_025720926.1\|2400455_2401913_+\|IMP-dehydrogenase	gnl\|CDD\|235507	PRK05567, PRK05567, inosine 5'-monophosphate dehydrogenase; Reviewed.	0
NZ_CP045298.1\|WP_025720930.1\|2403824_2404706_+\|pyridoxal-5'-phosphate-synthase-lyase-subunit-PdxS	gnl\|CDD\|179769	PRK04180, PRK04180, pyridoxal 5'-phosphate synthase lyase subunit PdxS.	0

>NZ_CP045298.1|WP_025720926.1|2400455_2401913_+|IMP-dehydrogenase
MWEDKFGKEGLTFDDVLLVPRKSEVLPKEVSVATRLSDSVKLNIPLMSAGMDTVTEAVLAIAMAREGGIGIIHKNMSIEQQAEEVDRVKRSESGVITNPFSLNPNHLVSDAEAVMGKYRISGVPIVNEENKLVGIITNRDLRFIHDFNLKISEVMTKEELVTAPVGTTLQEAEVILQKHKIEKLPLVDDENYLKGLITIKDIEKAIQFPNAAKDAQGRLLVGAAVGISKDTFDRTEALVKAGVDVIVVDSAHGHHINIIEAVRKLRSAYPDLTIVAGNVATGDGTRELIEAGASVVKVGIGPGSICTTRVIAGIGVPQVTAIYDCATVAREYNIPIIADGGIKYSGEITKAIAAGASAVMLGSLFAGTEESPGESEIYQGRRFKVYRGMGSMAAMKQGSKDRYFQDDDKKLVPEGIEGRVAYKGPLSDTVHQLLGGLRSGMGYCGTANIEELRNDTSFIRITGAGLRESHPHDVQITKEAPNYSL
>NZ_CP045298.1|WP_152380057.1|2393487_2394522_-|alpha/beta-fold-hydrolase
MKQRRRTWIRIVFFVISCLLLVVISGFVYEWIASKQDKSQYPPLGKMVDAGGYRLHIRKLGAGSPTILLESGSGESSLSWRDIPEKLSSFATVVSYDRAGYAWSEEAATPRTGENIVRELHVALKNADVQAPYILVGHSLGGMYSRLYAQTHRDEVAGLVLVDARPENDARRTNEIYAKEQPKVNPSPLVSILLEKSGAFRLFPNFMLAGRVEAQDRKSFVNIVASPKYFRSVAEEGDRASTTEDAIRGQHLGNLPVRVIARGIRQNLTQFGISKNGNDQIENSWQMGQREMLNISTNSKFIVAKKSDHMIIHDQPELVIQVIRELISITHRPQLTVTKTNTDD
>NZ_CP045298.1|WP_152380056.1|2366423_2393378_+|non-ribosomal-peptide-synthase/polyketide-synthase
MNNNVHQFFPLTNAQQRIWYTELLYPNTSVSLLLGTVKFKGKMNIDALKRSINMVIKQYDAFRIRITAEDGIPRQYVVPFEDKEFTCLDAADFKSIDEMNSWLEGHKQAPFELLNNELFQFLFIKISDDEYWLSVKMHHIISDGISMVLFGNQLTEYYVDIIRGIEPQLGKKYSYIEYIETEGAYVQSDRFAKDKEFWNDKFAGLPDVTGLKPYDPLLLSTVAQRAHFTVDGGLYKQIKQFCQDNKVSLFQFFMAAMYIYMHKAIGEQDIAIGTSLANRSTKKEKNTVGMFVSTIAARSFVDPDADLISFLQSVVKDQTTILRHQKYPYNQLIQDLRETYRSKDIQRLFGVSMEYRPVSWVDLDDVRIHTDYDFGGDEVNDLVLHIAEMLDEDQLVLHVDYRSRLFDASEIARIIRHLLVITEHIVENPEQKISEISLINEQEKNEILTVFNDTKADYPKDKTIHQMFEEQAERTPEQTAVVFGESQLTYRELNERANRLARTLRAEGVQADQLVGLMAERSLDMMVGIFAILKAGGAYVPIDPDYPEERIRYMLEDSGAKLLLLPSHLQDRVHFAGRILKLDEAQAYVLDGSNLEPVADPRDIAYVIYTSGSTGKPKGVMVEHRSVINRLIWMQEAYPLDAGDTILQKTAITFDVSVWELFWWSFVGASMCLLPVGGEKDPEVIVETIAAQRISTMHFVPAMLNAFLEYIERQGEEAQGKLASLKQVFASGEALTPNAAARFQQFVAPVGQAKLVNLYGPTEATVDVSYFNLQADETYRTIPIGKPISNIRLYIVSEGGKLQPIGVPGELCIAGDGVARGYLNRPELTAEKFVDSPFVPGERMYRTGDLARWQADGNIEYLGRIDHQVKIRGYRIELGEVETQLLKVEAVQETVVVAREDGSGQKQMCAYFTANAELTASELRGALAQELPGYMIPSYFVQLDQMPLSPNGKIDRKALPAPEEHMNTGEEYIAPRSEREAQLARIWQEVLGLKIVGIKDNFFEIGGHSLRATIVTARIQKEMNVGISLREVFQAPTIEQMAQLLDGREHVNYASIPRVEEQADYPVSSAQKRLYLLSQLEGGETSYNMPGVLMVEGSLDRTRAEEAFRQLIRRHETLRTSFDVVNGEPVQRVHPEVPFALEYAQATEEEAPAYIRRFVRAFDLRQAPLLRVGLIELEAERHLLLFDMHHIVSDGASINILVEEFNRLYEGEELPQLRIQYKDYAAWQLAEARSERLDKQAAYWLDVYRDELPVLELPTDYARPPVQSFAGSSIEFVVDKRQTHALQQLAAQTGSTLFMVLLSAYTALLHKYTRQEDIIVGTPIAGRPHADLEGMIGMFVNTLALRNSPAADKTFYQYVLEVKESALKAYENQDFPFEELVEKLDLRRDLSRNPIFDTLFVLQNTEQGNQEIEGLQFKSYAHPHQTAKFDLTLNVTENEEELACSLEYATALFQRETVERMTKHLLQLIDVILEKPETKLSSIEIITPQEKVRIVEQFNATTADYPHEKTIHQLFEEQAAESLAQVAVVYEDARLTYCELNERANRLARTLRDKGVVQDQPVAIAAHRSIELVVGVLAILKAGGAYVPIDPDYPAERIGYMLEDSGVKLLLIRRDDMADIGFAGSIIDLDDDAAYAEDGSNLGLTGGSGDLAYVIYTSGTTGRPKGVMVEHRNVVRLVKNTDYVQLDETTRILQTGAVVFDASTFEIWGALLNGGQLYLASNDVILDARKLRQAIEQYGITTMWLTSPLFNQLSQQDSKLFGAIKTLIVGGDMLSAPHINRVLRDNPGLDIVNGYGPTENTTFSTTYAIPGELTESAPIGRPIRNSTAYVVDSSMKLLPIGAWGELIVGGDGVARGYLNRPELTVEKFVQDPVKPGEICYRTGDLVRWRADGNLEIKGRIDEQVKIRGFRIELGEVEAQLAKIESIREAVVIARADESEQKQLCAYFAASNRLSAGEIRSALAKELPNYMIPSYFVQLEQLPLTANGKVDRRALPAPEENVHTGTEYAAPRTAVEQALASVWQSVLGVRNIGIHDSFFDLGGDSIKSIQVSSRLFQAGYKLEMKDMFKHPTIEGLSQYVQTVSRIAEQGEVSGATKLLPVQRWFFEQHSVSPHHFNQAVMLYREDGFEEAVLHQTMKKIAEHHDALRLVFRQTEHGYEAWNRGMAEGELYTLEIVDFKEQVAPEAAIQAKASEIQRGIDLIHGPLMKLGLFRCAEGDHLLIVIHHLAVDGVSWRILFEDIATGYEQAVNGQEIQLPQKTDSYRTWAQQLSLYAESPAMEHERAYWEQLGQIVAEPLPKDEVQTCPLVLDSETITIQWTEEETELLLKQANRAYNTETNDLLLTALGLAIQAWSGIGRVLVNLEGHGREPIIPDIDITRTVGWFTSQFPVTLEIGSNNDLSGQIKRIKESMRSIPHKGIGFGLLKYGSANLERVIRELKPEISFNYLGQFDQDLDNSSLQLSPYSTGGAISEHAVQAYTLDMNGMISEGTLSLAITYSSKQYRKETVERLSELIRTSLQKVIRHCTSKETAELTPSDILLKGLTIEQLDQLASHHRHVGEIENVYKLTPMQKGMFFHSLLEPHSLSYFEQATFEWHGHFDARSFAQSLDALVQRHAALRTNFYNGWGDPVQIVYRTKRSEFNYEDLRGMEQLQREAYIRNYIDDDRNRGFDLTQDPLLRVSVLHKGEADYLLMWSFHHIIMDGWCVPLITQEVFQTYFAISQQREPEFLPALPYSRYIEWLDRQDDQAAAEYWSDYLADYEQHTQIPQAKAQNKPEAYVSKQIVCELGKDLTGRIEQAAKRYQVTVSTLMQTVWGIVLQKYNSSRDVVFGSVVSGRPAEIPGIESMIGLFINTIPVRVRSDETISFADMVKRQQQQYLASHAYDTYPLYEIQTQTGQQHLITHIMVFENYPVEQQIELLGGEQAAFEITDAELFEQTNYDFNLIVLPGEEFKIVFRYNELVYEQSGIEQIQGHLIHMLEQVVSRPNIRVNELKLATPQEEAQMLLLGGSATTAYPKEKTIHQLFEEQAARSLAQVAVVYEDARLTYRELNERANRLARTLRDKGVVRDQPVAIAAHRSTELVVGVLAILKAGGAYVPIDPDYPAERIGYMLEDSGAKLLLIRRDDVADIGFAGSVIDLDDDAAYAEDGSNLGLTGASGDLAYVIYTSGTTGRPKGVMVEHRNVVRLVKSTDYVQLDETTRILQTGAVVFDASTFEIWGALLNGGQLYLASNDVILDAWELKQAIERYGITTMWLTSPLFNQLSQQDSKLFGTIKTLIVGGDMLSVPHANRVLRDNPGLGIVNAYGPTENTTFSTTYAIPGELTESAPIGRPICNSTAYVVDSSMKLLPIGAWGELIVGGDGVARGYLNRPELTMEKFVQDPVKPGEICYRTGDLVRWRADGNLEIKGRIDEQVKIRGYRIELGEVEAHLLQVESVQEAVVIAREDQTGQKQLAAYFAAEKMLPASELKAALAQELPAYMLPAYFVQVDRLPLTPNGKIDRKALPAPQEIETAGSRHEAPRTPIEASLANIWQEVLGLKSVGIKDNFFDIGGHSLRATLLMSRIHKELNGHIALREVFQFPTIEQMAEIIESRDQAAYASIPVVGERSYYPVSSAQKRLYVLSQIEGGEISYNMPGVMTVEGELDRTRLEAAFRQLIRRHETLRTSFDVVDGEPVQKVHEEVSFAVEYAEVREEEAREHVREFIRPFDLRQAPLLRVGLLRLQKDRHLLLFDMHHIVSDGASMNILIEEFIQLYEGAELPELRIQYKDYAVWQQLEVQSERIGKQEAYWLDTFRGELPVLDLPTDGVRPALQSFEGDQIEFVIDASRSEALKRLAASTGSTLYMVLLSAYTTLLHKYTGQEDVIVGTPIAGRPHGELEGLIGMFVGTLALRNYPAGEKKFLDYLQEVKETALQAYEHQDYPLEELVAKLNLKRDLSRNPLFDTMFALHNLEQGQREIADLQFKPYPHEHTAAKFDLMFNVTEQGSELACSLEYASMLFKRETAERIANHFLQVIDAVVSMPETKLSEIAIITAPEQAQILEQFNATAADYPKDKTIHQMFEEQAERTPEQTAIVLGESRLTYRELNERANRLARTLRAEGVQVDQRVGLMTERSLDMMVGIFAILKAGGAYVPIDPDYPEERIRYMLEDSGAKLLLLQSHLQDRIRFAGQILKLDEAQAYVQDDSNLAPVAGPRDMAYVIYTSGSTGKPKGVMVEHQSVINRLTWMQKVYPFDAGEIILQKTAITFDVSVWELFGWSSVGASLCLLPVGGEKDPEVILETIEAQRISRIHFVPAMLNVFLEYIERQGEQAQSKLASLKLVSTSGEALTPIAAARFQQLVAPVSQAKLVNLYGPTEATVEVSYFNLRADETYRTIPIGKPISNIRLYIVSEGGRLQPIGVPGELCIAGDGVARGYLNRPELTAEKFVDDPFVPGERMYRTGDLTRWQADGNIEYLGRIDHQVKIRGYRIELGEVETQLLKVEAVQETVVVAREDESGQKQMCAYFTANTELTASGLRGALAQELPGYMIPSYFVQLEYMPLNPNGKIDRKALPAPESSLSAGTAYEAPRTAVEQALAAVWQGALGVEKIGIHDNFFDLGGDSIKSIQVSSRLLQAGYKLDMKHLFKYPTIAELSPHVQTAGRIADQGEVMGETPLLPIQRWFFEQAPVDLHHFNHAVMLYRAEGFELTALRQTMAKIAEHHDALRLVFRQTEHGYEAWNRGIGEGELYTLDIADFRGEADYAAAIEAKASDIQRSINLSEGPLLKLGLFHCADGDHLLIVIHHLAVDGVSWRILFEDIAAGYEQAASGREIRLPQKTDSFRTWAQQLPQYAASPAMEIEREYWQQIVQTAAAIEPLPKDQKHDNPTRSDGETVTMQWSEEETLLLLKQANHAYNTEVNDLLLTALGMAIHAWTGTEQVLVSLEGHGREPIIPDADITRTVGWFTSQYPVVLEMAAEQDISRSIKRVKEGFRRIPNKGIGYGILTYLSGDGENEGHALRLQPEISFNYLGQFDQDLDSNKLQISPYSVGASISEKMAQRYTLDMNGMISQGVLSLTIDYNGRQYRKETMEKLSQLLRTSLREVILHCADKEQPELTPSDLLLSDLSMEELEQLVQQTAHIGEIENVYKLTSMQKGMLFHSQLEPDSAAYFEQAVFSLQGSLDVEIFAQSLDALVQRHDVLRTGFYSGLAEPVQVVYRRKPCGFYYEDLRGLEEAEREAYAQAFSVNDTAAGFDLAQDALLRVSVLRIGEQTYQFYWSFHHIIMDGWCVPIMMQEVFEHYAAIQEQRQPELSVVLPYRQYIEWLDQQSPEEAATYWSKYLEDYDQQTLLPQEIQENPQNKAAGYVAEELDCDLGGELTRRMESIAKQHQVTINTLMQSAWGLVLQRYNGSRDVVFGSVVSGRPAEITGIETMIGLFINTIPVRIRAEEGAAFTDVLKATQELALASSAYDTYPLYEIQAQTEQKQSLISHIMVFENYPMEQQIEQSASGDEDAFEITNVSMFDQTSYDFNLIVIPGEAIRISFRYNSLVYKQAGVALMQGHFMHVLEQITANPNLPVSELELATQEEMAQILEQFNATAADYPKDKTIHQMFEEQAERTPEQTAVVFGESRLTYRELNERANRLARTLRAEGVQADQLVGLMAERSLDMMVGIFAILKAGGAYVPIDPGYPEERIRYMLEDSGAKLLLLPSHLQDHIRFEGRTLKLDEAQAYEQDGSNLAPVAGPGDMAYVIYTSGSTGKPKGVMIEHRSVINRLIWMQEAYPLDAGDTILQKTAITFDVSVWELFWWSFVGASMCLLPVGGEKDPEVMVETIAAQGISTMHFVPAMLNAFLEYIEHQGEPAQSKLSSLKQVFTSGEALTPNAAARFQQFIAPASQAKLVNLYGPTEATVDVSYFNLQADEAYRTVPIGKPISNIRLYIVSEGGKLQPIGVPGELCIAGDGVARGYLNRPELTAEKFVDSPFVPGERMYRTGDLTRWQSDGNIEYLGRIDHQVKIRGYRIELGEVEAQLLKVEAVQEAIVVAKEDENGQKQMCAYFTANAELTASELRGALGQELPSYMIPSYFVQLEQMPLSPNGKIDRKALPAPEGNLLTGAKYDAPTTPVEARLAQIWKDVLGVGHVGIKDNFFEIGGHSLRATLLVSRIHKELNAPIALREVFQFPTIEQMAKMIESRDQAAYASIPTVGERSYYPVSSEQKRLYVLSQLEGGEISYNMPGVMTVEGELDRTRLEAAFRRLIRRHETLRTSFDVVNGEPVQRVHEEVPFTVEYIEAQEEEAKDRIRDFIRPFDLQQAPLLRAGLIKLQQDRHLLLFDMHHIVSDGTSMGVLTEEFMQMYEGSELPELRIQYKDYAVWQQTEMQSERIEKQEAYWLDVFRGELPILDLPIDETRPAERSFAGKQVDFVIDAAKGQALQQLAAQTGSTLYMVLLSAYTALLHKYTGQEDVIVGTPIAGRSHSDLEGLIGMFVGTLALRNYPSGEKSFLDYLQEVKETALQAYEHQDYPFEELVAKLNLNRDMSRNPLFDTMFVLQNTEQSEREIAGLQFKPYVYENQSAKFDLTLLIAEQGEELVCSFEYASALFKQETVERLASQFVQVIHTVVSAPETKLSKIAIITAQEQAQILEQFNAPAVDYPKDKPIHQMFEEQVERTPDQTAVVFGESRLTYRELNDRVNQLAHALRAEGVRSEQFVGLMVERSLEMVIGIFGILKAGGAYVPIDPEYPEERIHYILKDSGTKLLLTQSHLRQEKPDLASFEGKMVDLDSSQAYAEDRSNPGITVKPKDLMYLIYTSGTTGLPKGTMITQQGLVNYIWWAKKVYVGEEKLDFPLYSSISFDLTLTSIFTPLITGNTIFIYEGADKGTLIQEIIEDNQVDILKLTPTHLSLIKDMKMPDHSRIRKMIVGGENLSTHLAKSISDLFGGNIEIFNEYGPTETVVGCMIYLYDPVRDTKESVPIGVPADNVYIYLLDSQRNLVPPGVPGEMYIAGDGVALGYLNRPELTAEKFVDNPFAPGGRMYRTGDLARWQADGNIEYLGRIDEQVKIRGYRIELGEVEAQLMKVEAVQEAVVTARASEDGQKQLCAYLVADRSLTASELRGVLAKELPSYMIPSYFVQLERLPYTPNGKVDRKALPAPEGSLPTGTAYEAPRTAVEQALITVWQGVLGVGRIGIHDNFFDLGGDSIKSIQVSSRLLQAGYKLDMKHLFKYLTIAELSPHAQIVGHIVDQGEVTGATPLLPIQHWFFEQTPVDPHHYNHSVMLYRAEGFEQTALRQTLAKIAEHHDALRLVFRLNDHGYEAWNRGIGEGELYTLDIADFRGEADYAAAIEAKASDIQRSMNLSEGPLLKLGLFHCADGDHLLIVIHHLAVDGVSWRILFEDIAAGYEQAASGREIRLPQKTDSFRTWAQQLSLHAASPTMEHEREYWRQIVQTAAAIEPLPMDFAHPTAQVRDSETVVAGWSEEETSLLLKQANHAYNTEVNDLLLTALGMAVHAWTGTEQVLVNLEGHGREPIIPDTDITRTVGWFTSQYPVVLETGAEQDISRSIKRVKEGLRHIPNKGIGYGILAHLSDNGVNGDDSLQLKPEISFNYLGQFDQDLDSSKLQISPYSTGVAISENSVRNYVLDINGMISEGTLKLAISYCGNQYRKETMEKLAELIQSSLKAIILHCAGKEQSELTPSDLLLSDLSLEELEQLVQQTRHVGEIENVYKLAPMQKGMLFLSLLESNSGSYFEQSTFGIRGSLDMQVFAQSLDALMQRHDALRTNFYNGLAEPVQVVFRNRQSDFYCEDLRGMDQAQCDAYAENFNVQDRAKGFDLTRDALLRVSILRTGEENYSLIWSFHHIIIDGWCVPLLMQEVFEHYTAILEQRQPKLPPAPSYSTYIEWLDRQDAGKATDYWSKYLEDYEQQTLLPQVKAQGKVEGYRLEYTICDLGEDMTKQIELLAKQHQVTVSMLMQAAWGILLQRYNNSRDVVFGNVVSGRPADIPGIENMVGLFINTVPVRVQTEEGETFAQLLKKLQEQYLASHAYDTYPLYEIQALTEQKQSLINHVMVFENYPVEERLGQMRQNDRDEMEITVLEAFEQTNYDFVLTIEPGAQLKLHMRYNALVFEADTISRLQAHAVHLLEQLLDNPHSPVCDLGMITPEEQSQIIEVWGDTAAPYPREKTLHRIFEEQAALTPDRTALIYGEIELTYGELHRQANRLARTLRAQGVKPDQPVGIMVERSLEMIIGIHAILKAGGAYVPIDPEFPEDRIRHMLEDSGAKLLLTKNHLKDRFPFAGTLLALDDPQAYHADDSNLEPIAGPEHLAYIIYTSGSTGKPKGVMIEHRSAVHTLSQLETEYPMLAGDRFLLKTTFTFDFSVPELFCWFFGQGTLVILPQGVDKDPLALLEAVDTNRITHLNLVPSMLSVLVQYLKESDTQGFLTLKYLFACGETLPAKLVEEYYKVSPHAVLENIYGPTEAAVYATRYTTSPETAALTHVPIGKPYANVQVWMMDSASQVSPVGVPGELCIAGEGVARGYFNQPELTAEKFIPHPYKPGARIYRTGDLARWLPDGNIEYLGRIDHQVKIRGYRIELGEVEAQILKVPSVQEAVVLALADATGSTQLCAYFVAEEGLAAGVLREALANELPSYMIPTAFVQLAQMPLNPNGKLDRKALPAPEALLRSTAEYIPPRTPTEVELAHIWSEVLGVQEIGVKDHFFELGGHSLKVLGLIQKISTGMGVQLPLQLVFNLPTVEEMAQEIFKLRAKAASDEEEMEILHFPGKGDLKVFCFPPRVGYSLGYYEMARELEGHCEVYGFEFIGDRVQGQDMLDRYVDAIEGIQAEGPYVFLGYSLGGNLAFEVAKAMESRGHQVSDLIMVDAMRKTSKDESTPEQLEEIVETVLDSIEDQYKAFLADPSDRERVKEKILIYSIYRNELVNEGEVQANIHALIAEDDTIGPVTSSDKLLWQQSTHGQYEEYGIIGTHDVLLDSGYVGENAKVLRQILGKVAEASSKSKPILS
>NZ_CP045298.1|WP_152380055.1|2365945_2366362_+|beta-hydroxyacyl-ACP-dehydratase
MNADDIRILDVLPHRYPFIMIDKVTGFENSKWARGYKNVTWNDWFVSEANPFMPHMMVVEALAQLGGFATMDETGISFLSSLNQVEMHEWAQPGDRLDLYFEVTKRKRGFLLGKGLATVGDRIIVKAEEIVSYTPKQV
>NZ_CP045298.1|WP_152380054.1|2364699_2365941_+|beta-ketoacyl-ACP-synthase-II
MRRRVVVTGQGVVTPVGLNLSDFWNSLLEGKSGIGPVTVFDTADIPTKIGAQVTGFDPLQYMSKKEANKVAQFTQFALAAARQAVEQSKLVIDERNASRVGVIVGSGAGGLDVIEENYRKLTELGPKRVSPYFVSSMMINSAPGEISIAIGAKGPSFAVVTACATGSNAIGEALRTIQYGTADVVVAGGAEANFSQLDLASFANIHALSRRNEEPQKASRPFDVDRDGFVIGGGAGVLVLEELEHALNRGATILAEVAGYGCTTDAYHITAPDPSGSGPAEAISIALQDGGLTPQEIDYVNAHGTSTPFNDRMEINAIQSVFGAHAPRLAISSIKSMTGHLMGGAGAVELIATVQSLLHNKVPPTLNCDNPEAPELNFVPHVYQEREVRAAISNSFGFGGHNVCLAVRKWLGE
>NZ_CP045298.1|WP_152380053.1|2362975_2364676_+|thiamine-pyrophosphate-binding-protein
MTASLLPWDAIIGYIKSAGVRHLFGLPSDDLKIVSSLPSSGMDFILCKDQRNAVFMAAGYALTTNQMSVCVVGKGPALSNTLTGLLEAKNLGAPLLLLALGTGGDKLGTRSFQEADQISLVKPLVKWAYRVEHVDRLVWALERAAFLAINGAPGPVYIELPENLMDQPLPTGLQFTPPEKLSCSPSLRELDAAWELIKTARRPVILVGGGMKSVTNDVIEVFANQHGAALFATASGRGAVDEDHELFCGVAGLYTDLSLRQIWKESDVVITLGSRLEETATFEWDILLENTPLIQVNVELEDFAHEYRGIKVLGDGYAALEQWVQRYGHKPDEVWLETIRSCKEKAFSNRAIYLEELKKTPGIHVPELLEIIQTEFPENLVLLQENGLQDMWSYFYPYFRFTQGSLSIVPSDQTSLGFGAAAALGASVATERPVVALVGDGAFNLFYSDFMTAVQYQIPLIYIVLNNGGYGWLQNQMNYKHLSDQSLPFVSEEAKAGIQIPQYEFVESLAIRSKGEAQEQLRLAWEKYQENKLVVVEVYANLADVHEKISHVYGDFPLYEQQASKN
>NZ_CP045298.1|WP_152380052.1|2361755_2362979_+|aldehyde-dehydrogenase-family-protein
MSMNPELEKNKLFLERHEAILKCLNYLIEHRQEVMDILTQFSSYRAANAEIDSTILTLQGALEEVQTYQPGWQRSMAVFMPSNVVLYSYALYLLIPALYVENIDFRPSSHVNEYVSMLHEKLQAVHGLPIYIRKVSQKVFMENSVMPADIVVFTGSYTNAEKIKKQIRKEQLYIFYGQGINPFIIGPDADLELAVTDVTRMRLYNSGQDCLGPDIILVHQDVRESFKNLLIKRLDQLVFGANNDPNANYSPIFYKDTLYSVSEYFNTNDKFIIYGGGIDFRTKKMEPTVVYSELDENLEIIEYFSPVFNVVIYRDDEQLIKRISSSYFSERAMGCSLYGSEHLSDVLRKKHTLTINQTLEDVDQGNKPFGGYGTMSNYIFYDFKLVSKPILISEIVAEYLSEKRSLV
>NZ_CP045298.1|WP_152380051.1|2360196_2361657_+|AMP-binding-protein
MLVTHTDCRIISPEGIMTRERLERDVVIFSRMLALRGISEEGRVILKAANSYYFIVSLFSLCNIAVSVTVVDEQTVHDEVAQIYDEADACCILTDCDPGLSHASVILIQDLIQEEAVHPHWVGEPEIYGIDFNKWCERSDALILYSSGTTGKPKGIVKAGSAFMDNIRHSIHAMNYLPSDHMLPVVPFSHFYGISLIFSWWLTSCSLIICNPKNLWSVIASITKDRATVVDANPSAFYTLLRMLNRKPEQLEMVKESPVRMWCVGGSPLTQDLEDKFNNIFGQPLLNGYGLSELGNVTLGTLECPQGCGKPLPGVDLKILDAAGSQQADGIVGEVWIRSAGCMEGYLNRPDLTQSVLQDGWFKTGDLGYLDDEMLYVIGRSGKTVNRMGYMVSPVYIEDRIGSLGYRSCVITLEDEAKGTLLIAYIEGESSQALSVLRKEMNRVLPSYMFPDLLLPLAHFPLNRNGKVNRLEMERIALEKVASRKV
>NZ_CP045298.1|WP_152380050.1|2359413_2360184_+|SDR-family-oxidoreductase
MAALLSGKNILIMGVANNRSIAWGTAQSLAAEGARLIFTYENERVADRVLKLVDTIPGSIVCPCNVQSDEELDTLADFLKEKVGVLHGYFHSVAYAKAEDLDGLFVDTSREGFAIAQEISAYSLAAVSRRIYPLMTEGGSIVTMTYIGAERAIKNYNVMGVAKASLEAGMRYLSNDLGTYGIRVNAISAGPIRTLAAYGIKDFSTMLKHIEETTPLRKTVDTSEVGDTALFLFSHLSRGITGEVIHVDAGYHITGM
>NZ_CP045298.1|WP_152380049.1|2358123_2358651_+|hypothetical-protein
MYIFIISAEVLFWVFVVAGLIARYMYDLKKLGGLLLLCTPVIDILLLIAVFITVSSGMEITTATGLAACYLGITVAFGHRLIKWADVRFSYWFGKGPKPQRKYGAAHAKEERTTWLLHLLGWAIGNVLLLAIIVYVGDLQRTASLEGLMKTWAVVLAIDFIVSFSYTLAPKKNKA
>NZ_CP045298.1|WP_152380058.1|2402303_2403692_+|D-alanyl-D-alanine-carboxypeptidase
MKANNQKQNSKRSMIKKSVTAVMALNMMYMSALPVVGNFDPTVATFAAGATTEATKITGTGSVNPPSLALRSAILIEPSTGQVLLSMNPDEPLPPASMTKMMTEYIVAEQVKQGKLKWTDKVTVNENAAKSIGSRIFLAQGDQHTVEELYIAMAVGSANDATVALAERVSGTEQDFVKLMNETAQKMGMKNTYFINSTGLDRKDMPKAYQPNTDRETVMTARDAAILASNIIKDHPDYKRFTTIQSYKFRPTDKAPIVNYNWMLEANKNITNFRKFAYPGLDGMKTGHTTNAGNCFTGTAERNGMRLISVVMGADSEPHRFTETAKVLNYGFDNFEVKQVVAPKTVVKGIENVPVTKGKETEVPVVTKDAVSFIVPKGASNPKVTFTTKITPASSLVAPLKQGAKVGTITYTYKTDGSDKGQMKTVDLVTATAVEEGGWFRMLFRAIGDFFGNLFQSIKNLF
>NZ_CP045298.1|WP_025720930.1|2403824_2404706_+|pyridoxal-5'-phosphate-synthase-lyase-subunit-PdxS
METGTSRVKRGMAEMQKGGVIMDVMNAEQAKIAEAAGATAVMALERVPSDIRAAGGVARMADPTIVEEVMKVVSIPVMAKARIGHFVEAKVLESLGVDYLDESEVLTPADEVFHIDKREFTVPFVCGAKDLGEALRRIGEGASMIRTKGEPGTGNIVEAVRHMRFINGQIRKVQNLSKDELYAEAKNLGVAYELLLEVHEHGKLPVVNFAAGGVATPADAALMMHLGADGVFVGSGIFKSDSPEKFARAIVEATTHYTDYKLIAEVSKNLGTPMKGIEISKLAPHERMQDRGW
>NZ_CP045298.1|WP_025720931.1|2404723_2405290_+|pyridoxal-5'-phosphate-synthase-glutaminase-subunit-PdxT
MKIGVLSLQGAVAEHIRSIECAGAEGVTVKKIEQLNELSGLIIPGGESTTIGKLMRKYEFIDAIRQFSDQGKPIFGTCAGLIVLAKKIQGQEEAHLGLMDITVSRNAFGRQRESFETDLNIKGIEQPVRAVFIRAPLIMSVGTGVDVLSEYNGEIVAARQGHLLASSFHPELTDDYRLHQYFVDMVRE
>NZ_CP045298.1|WP_152380059.1|2405328_2406612_+|serine--tRNA-ligase
MLDIKILRNELGRVEKALQNRGKSLDLINGFTDLDVSRRELLQESEALKNRRNVVSGEVAKLKKNKENADDLIAEMRQVSDRIKELDDQVRELEVQIDELVMSIPNIPNDTVPVGASEEDNVEIRRWSEPLEFSFTPKAHWELAQNLDILDFEAAAKVTGSRFTFYKGLGARLERALINFMMDLHSSEHGYEEMLPPYIVNRDSLYGTGQLPKFEEDLFKLRDTEYYLIPTAEVPVTNYHREEIMNAEQLPKYYVAYSSCFRSEAGSAGRDTRGLIRQHQFNKVEMLKLVHPDTSYEELEKMTNDAERVLQLLGLPYRVLALCTGDMGFTSAKTYDLEVWLPESGMYREISSCSNTEDFQARRANIRFRPDSKAKPEFVHTLNGSGLAVGRTVAAILENYQQEDGSIVIPEVLRPYMRGVEVITPKQ
>NZ_CP045298.1|WP_025720936.1|2406934_2407276_+|hypothetical-protein
MNREMTVDQQKLVEAWQEQLPILLNSGDKAQVQADEADSRTIRIHIEVEGRQMYSFDFACTYVDSREVQVNLVDVERDGKTVDERTDIIQQLVSDYTRHIHQCAQTLQSLTHS
>NZ_CP045298.1|WP_007428073.1|2407304_2407475_+|hypothetical-protein
MTKAKNGLDKNLSNIVDDLEQRPVNSHQAQQVQQDRNDRRHQDSLNHDKTEDLHHL
>NZ_CP045298.1|WP_025720938.1|2407546_2407702_+|small-acid-soluble-spore-protein-P
MSKPKAIPVPEAQDSGGGNERRERNHQQEPLSGSKKVKQRNHVDHHNREGS
>NZ_CP045298.1|WP_152380060.1|2407900_2408977_+|hypothetical-protein
MSKKLSVLVLTMVLLLMVALVGCSKKLEPKEAVTTGTANAMKLNSYESKSQFTVKDLTISSATLPSQQSAMITSMLKNADITLDGVYQKEPLQSEMTLGIHLKGDLSTSFTIPMVMTKDKLYVKIPNIPFYPLPQDVVGKFLIIDPQELAKKSGQEFNPATMDQEKSQKFANEVIAAIMGEYDQATYFFDIDPKDAKLPQGVEAKQVVQFKITNDNVKQAVDTFVTKAIPKVFDIMSKDEYTSLFQLKKEDLTAAKLAVETNTSDFKKKLDELKNYLTVKQFDINTALNKDNIPVYQDLNANVEMNDPATKDNVKLSVTGYTQYSKINEKATFKVGIPTSDQVLTIEQLQQKMQTVAP
>NZ_CP045298.1|WP_152380061.1|2409087_2409651_-|GNAT-family-N-acetyltransferase
MPMSLYNTPQGIFLRLIGLKDSESLLALRMRNRESCAPYEPLYEDSFFTLEKQQDYIRQKLLQTEEDRGYMFGIFLLKEERLIGYISISNLVRGAGQFADIGYMIDQLQGSGHMTAALKLIIQYAFRALSLHRLQAGTLLHNVRSQRVLEKCGFQPEGIARKLVQIQGTWQDHQMFALLAEDDVWQT
>NZ_CP045298.1|WP_025720943.1|2409730_2410231_-|tRNA-adenosine(34)-deaminase-TadA
MTIMDHAYWMKEAIQEAYKAEALGEVPIGAVIVKDNEIIGRGYNLRETDADPTAHAEIIAIRQASEHLGAWRLLDCRLYVTLEPCPMCAGAIVQSRIPHLIYGTTDPKAGCAGTLMNLLQEPRFNHCTEVTSGVLQEECASLLTNFFRNLRQKRAAAKLSSPPPSS

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Crispr_ID: NZ_CP045298_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045298_3

2713495-2714536

Orphan

I-C

Consensus_repeat	Method
ATTTCAATCCACGCACCCACATGGAGTGCGAC	PILER-CR
ATTTCAATCCACGCACCCACATGGAGTGCGAC	CRISPRCasFinder
ATTTCAATCCACGCACCCACATGGAGTGCGAC	CRT

15 spacers

The CRISPR arrays of NZ_CP045298_3

>merge|NZ_CP045298|3|2713495-2714536|PILER-CR,CRISPRCasFinder,CRT
ATTTCAATCCACGCACCCACATGGAGTGCGACTTAAATCATCGTTCCAGCCCATTGCAGCTTTCTGATTTCAATCCACGCACCCACATGGAGTGCGACACAGAAATACTCCAGCATAAACGATATGTTATCGGTATTTCAATCCACGCACCCACATGGAGTGCGACGTACAGGACTCACGTTGACACCGCGTAGCCGGCGTAAATTTCAATCCACGCACCCACATGGAGTGCGACTTCTTTTCGATACTCCCCACACCCTCAAAGCCGTTAATTTCAATCCACGCACCCACATGGAGTGCGACTTACCAACGGCAACACAGTATCATGCGGCTGTAAACATTTCAATCCACGCACCCACATGGAGTGCGACTCTCTAAGTTGATCTTTGCAACTACGTCCTTACGTGCAATTTCAATCCACGCACCCACATGGAGTGCGACACCGTTAAGCTGTTTAATCCAAGGTACAATACCAATTTCAATCCACGCACCCACATGGAGTGCGACTTGAAGAGTTTAAGGGAGTAAAGGCGTGGCTTGATAATTTCAATCCACGCACCCACATGGAGTGCGACACTGGTTCAGTCTTGGGAACTGGAGCCTGAGGAGATTTCAATCCACGCACCCACATGGAGTGCGACCCATCCGGGTCAAGAGGACCGCCATCATCCATTCTAATATTTCAATCCACGCACCCACATGGAGTGCGACCGGTCCAGCGCGTGCCGGCGAGTTTGACGTCCTCATTTCAATCCACGCACCCACATGGAGTGCGACGGCGCAAGCAAGGGGTGGTTCGAAATCAACGAAAAATTTCAATCCACGCACCCACATGGAGTGCGACGTGTTACTTTGAAGGGATTTGTTTACATCTTCACATTTCAATCCACGCACCCACATGGAGTGCGACCATCGTCCGTCATGCCAACCCTTTGCGGTATCCAATTTCAATCCACGCACCCACATGGAGTGCGACGGGCTTGTGATTCGGTCCGGCGGCTCGCTGGATGATTTCAATCCACGCACCCACATGGAGTGCGAC

>NZ_CP045298|3|2|2713495-2714536|PILER-CR
ATTTCAATCCACGCACCCACATGGAGTGCGAC	TTAAATCATCGTTCCAGCCCATTGCAGCTTTCTG
ATTTCAATCCACGCACCCACATGGAGTGCGAC	ACAGAAATACTCCAGCATAAACGATATGTTATCGGT
ATTTCAATCCACGCACCCACATGGAGTGCGAC	GTACAGGACTCACGTTGACACCGCGTAGCCGGCGTAA
ATTTCAATCCACGCACCCACATGGAGTGCGAC	TTCTTTTCGATACTCCCCACACCCTCAAAGCCGTTA
ATTTCAATCCACGCACCCACATGGAGTGCGAC	TTACCAACGGCAACACAGTATCATGCGGCTGTAAAC
ATTTCAATCCACGCACCCACATGGAGTGCGAC	TCTCTAAGTTGATCTTTGCAACTACGTCCTTACGTGCA
ATTTCAATCCACGCACCCACATGGAGTGCGAC	ACCGTTAAGCTGTTTAATCCAAGGTACAATACCA
ATTTCAATCCACGCACCCACATGGAGTGCGAC	TTGAAGAGTTTAAGGGAGTAAAGGCGTGGCTTGATA
ATTTCAATCCACGCACCCACATGGAGTGCGAC	ACTGGTTCAGTCTTGGGAACTGGAGCCTGAGGAG
ATTTCAATCCACGCACCCACATGGAGTGCGAC	CCATCCGGGTCAAGAGGACCGCCATCATCCATTCTAAT
ATTTCAATCCACGCACCCACATGGAGTGCGAC	CGGTCCAGCGCGTGCCGGCGAGTTTGACGTCCTC
ATTTCAATCCACGCACCCACATGGAGTGCGAC	GGCGCAAGCAAGGGGTGGTTCGAAATCAACGAAAA
ATTTCAATCCACGCACCCACATGGAGTGCGAC	GTGTTACTTTGAAGGGATTTGTTTACATCTTCAC
ATTTCAATCCACGCACCCACATGGAGTGCGAC	CATCGTCCGTCATGCCAACCCTTTGCGGTATCCA
ATTTCAATCCACGCACCCACATGGAGTGCGAC	GGGCTTGTGATTCGGTCCGGCGGCTCGCTGGATG
ATTTCAATCCACGCACCCACATGGAGTGCGAC

>NZ_CP045298|3|3|2713495-2714536|CRISPRCasFinder
ATTTCAATCCACGCACCCACATGGAGTGCGAC	TTAAATCATCGTTCCAGCCCATTGCAGCTTTCTG
ATTTCAATCCACGCACCCACATGGAGTGCGAC	ACAGAAATACTCCAGCATAAACGATATGTTATCGGT
ATTTCAATCCACGCACCCACATGGAGTGCGAC	GTACAGGACTCACGTTGACACCGCGTAGCCGGCGTAA
ATTTCAATCCACGCACCCACATGGAGTGCGAC	TTCTTTTCGATACTCCCCACACCCTCAAAGCCGTTA
ATTTCAATCCACGCACCCACATGGAGTGCGAC	TTACCAACGGCAACACAGTATCATGCGGCTGTAAAC
ATTTCAATCCACGCACCCACATGGAGTGCGAC	TCTCTAAGTTGATCTTTGCAACTACGTCCTTACGTGCA
ATTTCAATCCACGCACCCACATGGAGTGCGAC	ACCGTTAAGCTGTTTAATCCAAGGTACAATACCA
ATTTCAATCCACGCACCCACATGGAGTGCGAC	TTGAAGAGTTTAAGGGAGTAAAGGCGTGGCTTGATA
ATTTCAATCCACGCACCCACATGGAGTGCGAC	ACTGGTTCAGTCTTGGGAACTGGAGCCTGAGGAG
ATTTCAATCCACGCACCCACATGGAGTGCGAC	CCATCCGGGTCAAGAGGACCGCCATCATCCATTCTAAT
ATTTCAATCCACGCACCCACATGGAGTGCGAC	CGGTCCAGCGCGTGCCGGCGAGTTTGACGTCCTC
ATTTCAATCCACGCACCCACATGGAGTGCGAC	GGCGCAAGCAAGGGGTGGTTCGAAATCAACGAAAA
ATTTCAATCCACGCACCCACATGGAGTGCGAC	GTGTTACTTTGAAGGGATTTGTTTACATCTTCAC
ATTTCAATCCACGCACCCACATGGAGTGCGAC	CATCGTCCGTCATGCCAACCCTTTGCGGTATCCA
ATTTCAATCCACGCACCCACATGGAGTGCGAC	GGGCTTGTGATTCGGTCCGGCGGCTCGCTGGATG
ATTTCAATCCACGCACCCACATGGAGTGCGAC

>NZ_CP045298|3|2|2713495-2714536|CRT
ATTTCAATCCACGCACCCACATGGAGTGCGAC	TTAAATCATCGTTCCAGCCCATTGCAGCTTTCTG
ATTTCAATCCACGCACCCACATGGAGTGCGAC	ACAGAAATACTCCAGCATAAACGATATGTTATCGGT
ATTTCAATCCACGCACCCACATGGAGTGCGAC	GTACAGGACTCACGTTGACACCGCGTAGCCGGCGTAA
ATTTCAATCCACGCACCCACATGGAGTGCGAC	TTCTTTTCGATACTCCCCACACCCTCAAAGCCGTTA
ATTTCAATCCACGCACCCACATGGAGTGCGAC	TTACCAACGGCAACACAGTATCATGCGGCTGTAAAC
ATTTCAATCCACGCACCCACATGGAGTGCGAC	TCTCTAAGTTGATCTTTGCAACTACGTCCTTACGTGCA
ATTTCAATCCACGCACCCACATGGAGTGCGAC	ACCGTTAAGCTGTTTAATCCAAGGTACAATACCA
ATTTCAATCCACGCACCCACATGGAGTGCGAC	TTGAAGAGTTTAAGGGAGTAAAGGCGTGGCTTGATA
ATTTCAATCCACGCACCCACATGGAGTGCGAC	ACTGGTTCAGTCTTGGGAACTGGAGCCTGAGGAG
ATTTCAATCCACGCACCCACATGGAGTGCGAC	CCATCCGGGTCAAGAGGACCGCCATCATCCATTCTAAT
ATTTCAATCCACGCACCCACATGGAGTGCGAC	CGGTCCAGCGCGTGCCGGCGAGTTTGACGTCCTC
ATTTCAATCCACGCACCCACATGGAGTGCGAC	GGCGCAAGCAAGGGGTGGTTCGAAATCAACGAAAA
ATTTCAATCCACGCACCCACATGGAGTGCGAC	GTGTTACTTTGAAGGGATTTGTTTACATCTTCAC
ATTTCAATCCACGCACCCACATGGAGTGCGAC	CATCGTCCGTCATGCCAACCCTTTGCGGTATCCA
ATTTCAATCCACGCACCCACATGGAGTGCGAC	GGGCTTGTGATTCGGTCCGGCGGCTCGCTGGATG
ATTTCAATCCACGCACCCACATGGAGTGCGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045298.1\|WP_152380218.1\|2702293_2703118_+\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223472
NZ_CP045298.1\|WP_152380219.1\|2703148_2704930_+\|histidine-kinase	unknown	unknown	gnl\|CDD\|225519
NZ_CP045298.1\|WP_152380233.1\|2723775_2724495_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045298.1\|WP_152380224.1\|2709628_2710090_+\|pyridoxamine-5'-phosphate-oxidase-family-protein	unknown	unknown	unknown
NZ_CP045298.1\|WP_152380221.1\|2706181_2707093_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_CP045298.1\|WP_152380229.1\|2718781_2719660_+\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|372253
NZ_CP045298.1\|WP_152380228.1\|2717801_2718785_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP045298.1\|WP_167518686.1\|2721724_2721946_+\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	unknown	unknown	gnl\|CDD\|377551
NZ_CP045298.1\|WP_152380230.1\|2720598_2721486_+\|NmrA-family-NAD(P)-binding-protein	unknown	unknown	gnl\|CDD\|187561
NZ_CP045298.1\|WP_152380225.1\|2711177_2712233_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|293786
NZ_CP045298.1\|WP_152380227.1\|2716698_2717805_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045298.1\|WP_152380222.1\|2707899_2709276_+\|UbiD-family-decarboxylase	unknown	unknown	gnl\|CDD\|129252
NZ_CP045298.1\|WP_167518687.1\|2725534_2726179_-\|S-layer-homology-domain-containing-protein	unknown	unknown	gnl\|CDD\|306825
NZ_CP045298.1\|WP_152380223.1\|2709332_2709569_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045298.1\|WP_167518685.1\|2699492_2699651_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045298.1\|WP_152380220.1\|2704926_2706111_+\|response-regulator	unknown	unknown	gnl\|CDD\|381091
NZ_CP045298.1\|WP_152380226.1\|2716151_2716670_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|236602
NZ_CP045298.1\|WP_152380232.1\|2723300_2723696_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045298.1\|WP_152382149.1\|2715649_2715739_-\|transposase	unknown	unknown	gnl\|CDD\|379129
NZ_CP045298.1\|WP_152380217.1\|2699944_2701276_+\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|270452

Protein	Function_ID	Function_description	E-value
NZ_CP045298.1\|WP_152380218.1\|2702293_2703118_+\|ABC-transporter-permease-subunit	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	9.1996e-73
NZ_CP045298.1\|WP_152380219.1\|2703148_2704930_+\|histidine-kinase	gnl\|CDD\|225519	COG2972, COG2972, Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms].	1.72993e-46
NZ_CP045298.1\|WP_152380217.1\|2699944_2701276_+\|extracellular-solute-binding-protein	gnl\|CDD\|270452	cd14749, PBP2_XBP1_like, The periplasmic-binding component of ABC transport systems specific for xylo-oligosaccharides; possesses type 2 periplasmic binding fold. This group represents the periplasmic component of an ABC transport system XBP1 that shows preference for xylo-oligosaccharides in the order of xylotriose > xylobiose > xylotetraose. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.64899e-102
NZ_CP045298.1\|WP_152380221.1\|2706181_2707093_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	1.28448e-54
NZ_CP045298.1\|WP_152380229.1\|2718781_2719660_+\|ABC-transporter-permease-subunit	gnl\|CDD\|372253	pfam12679, ABC2_membrane_2, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family.	1.70621e-09
NZ_CP045298.1\|WP_152380228.1\|2717801_2718785_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	8.75955e-79
NZ_CP045298.1\|WP_152380225.1\|2711177_2712233_+\|hypothetical-protein	gnl\|CDD\|293786	sd00045, ANK, ankyrin repeats. Ankyrin repeats are one of the most abundant repeat motifs, and generally function as scaffolds for protein-protein interactions in processes including cell cycle, transcriptional regulation, signal transduction, vesicular trafficking, and inflammatory response. Although predominantly found in eukaryotic proteins, they are also found in some bacterial and viral proteins. Less is known of their physiological roles in prokaryotes. Some bacterial ANK proteins play key roles in microbial pathogenesis by mimicking or manipulating host function(s). The pathogen Providencia alcalifaciens N-formyltransferase ankyrin repeats function in small molecule binding and allosteric control. Ankyrin-repeat proteins have been associated with a number of human diseases.	7.46182e-18
NZ_CP045298.1\|WP_152380222.1\|2707899_2709276_+\|UbiD-family-decarboxylase	gnl\|CDD\|129252	TIGR00148, Uncharacterized_protein, UbiD family decarboxylase. The member of this family in E. coli is UbiD, 3-octaprenyl-4-hydroxybenzoate carboxy-lyase. The family described by this model, however, is broad enough that it is likely to contain several different decarboxylases. Found in bacteria, archaea, and yeast, with two members in A. fulgidus. No homologs were detected besides those classified as orthologs. The member from H. pylori has a C-terminal extension of just over 100 residues that is shared in part by the Aquifex aeolicus homolog. [Unknown function, General].	0
NZ_CP045298.1\|WP_167518687.1\|2725534_2726179_-\|S-layer-homology-domain-containing-protein	gnl\|CDD\|306825	pfam00395, SLH, S-layer homology domain.	5.21391e-10
NZ_CP045298.1\|WP_152380230.1\|2720598_2721486_+\|NmrA-family-NAD(P)-binding-protein	gnl\|CDD\|187561	cd05251, NmrA_like_SDR_a, NmrA (a transcriptional regulator) and HSCARG (an NADPH sensor) like proteins, atypical (a) SDRs. NmrA and HSCARG like proteins. NmrA is a negative transcriptional regulator of various fungi, involved in the post-translational modulation of the GATA-type transcription factor AreA. NmrA lacks the canonical GXXGXXG NAD-binding motif and has altered residues at the catalytic triad, including a Met instead of the critical Tyr residue. NmrA may bind nucleotides but appears to lack any dehydrogenase activity. HSCARG has been identified as a putative NADP-sensing molecule, and redistributes and restructures in response to NADPH/NADP ratios. Like NmrA, it lacks most of the active site residues of the SDR family, but has an NAD(P)-binding motif similar to the extended SDR family, GXXGXXG. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Atypical SDRs are distinct from classical SDRs. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	3.90157e-77
NZ_CP045298.1\|WP_167518686.1\|2721724_2721946_+\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	gnl\|CDD\|377551	pfam05717, TnpB_IS66, IS66 Orf2 like protein. This protein is found in insertion sequences related to IS66. The function of these proteins is uncertain, but they are probably essential for transposition.	1.8667e-27
NZ_CP045298.1\|WP_152380220.1\|2704926_2706111_+\|response-regulator	gnl\|CDD\|381091	cd17536, REC_YesN-like, phosphoacceptor receiver (REC) domain of YesN and related helix-turn-helix containing response regulators. This family is composed of uncharacterized response regulators that contain a REC domain and a AraC family helix-turn-helix (HTH) DNA-binding output domain, including Bacillus subtilis uncharacterized transcriptional regulatory protein YesN and Staphylococcus aureus uncharacterized response regulatory protein SAR0214. YesN is a member of the two-component regulatory system YesM/YesN and SAR0214 is a member of the probable two-component regulatory system SAR0215/SAR0214. Also included in this family is the AlgR-like group of LytTR/AlgR family response, which includes Pseudomonas aeruginosa positive alginate biosynthesis regulatory protein AlgR and Bacillus subtilis sensory transduction protein LytT, among others. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	2.74434e-42
NZ_CP045298.1\|WP_152380226.1\|2716151_2716670_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|236602	PRK09639, PRK09639, RNA polymerase sigma factor SigX; Provisional.	1.57158e-36
NZ_CP045298.1\|WP_152382149.1\|2715649_2715739_-\|transposase	gnl\|CDD\|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	3.2276e-06

>NZ_CP045298.1|WP_152380225.1|2711177_2712233_+|hypothetical-protein
MGKKKKTLPANFDELVKTNDISALKEVFELCEWDARGGYSKGTALSFRQIPDEMVRWLVEQGADINAADNYKRTPIHAQAATWSGNVSLLLELGADLEALDYQNETPLHSAAASYRTKAVRDLVIRGANVHAENKQKNTPLARGLLQCRNIDIVHMAEISGIMLDAGAAITPGMKESVRRIGKDFEFARTNYNKDQLQETENALLELYRKFDVEPIVKLEKHDGISPIKVTAASWPAQHQELWDVLVPASGHAKTVQGEVIRITGRVSHEILNNGGGNWDANYRKMLDALILHFSTGTPLAPVLLHEAAALSNRFRNIAGNEQPARLSELAVQWVLANPHPISMTQPDYSR
>NZ_CP045298.1|WP_152380224.1|2709628_2710090_+|pyridoxamine-5'-phosphate-oxidase-family-protein
MQTPRIGKELFMLLDGKTLENKQHEAMMLLTVTEDQWPHIAMISVGEIVALDEGNLRLALWPGTTTTGNMIRTGKATLAVFIGGKAHYVRLSLEHLPMLPGAKHVRERFAARVFAAREDSAQYADIVAGVTIRLKESEVVLNRWKETVTELLM
>NZ_CP045298.1|WP_152380223.1|2709332_2709569_+|hypothetical-protein
MHICPRCESNRSEVVSHSPVEGAWEVLLCPVCLFTWRTSEPDSITDPAKYKSAFKVDPRDIPNAIHVPLIAERRQDRS
>NZ_CP045298.1|WP_152380222.1|2707899_2709276_+|UbiD-family-decarboxylase
MAYKDFRDFLHALEKEGQLLTISDEVKPEPDIAAANRALNNLGDKTPALFFNNIYGYTDARIVMNVMGSWPNDALMMGMPKNTPLKEQFFEFARRYEQFPVPVKREETAPFHEVEITEDINLFDILPLFRLNQGDGGFYLDKAILVSRDLDDPDTYGKQNVGLYRMQVKGKNRLGIQPVPQHDIAIHIRQAEERGENLKVAIALGCEPVITTAASTPLLYDQSEYEMAGAIQGEPYRVVKAKDADLDLPWGAEIILEGEVLAGEREYEGPFGEFTGHYSGGRAMPVIQINRVYHRKQPIFEHLYIGMPWTETDYMIGVNTSVPLFQQLKDAFPNEIVAVNAMYTHGLVAIISTKTRYGGFAKAVGMRALTTPHGLGYCKLVIVVDEDVDPFNLPQVMWALSTKLHPKHDAVIVPGLSVLPLDPGSDPAGMTHKMILDATTPVAPDIRGHYSQPLGRKS
>NZ_CP045298.1|WP_152380221.1|2706181_2707093_-|LysR-family-transcriptional-regulator
MDIKHLHYFCVIVEEGQITKAARMLNMAQPPLSQQLKNMEDELGVKLIYREGKKWEVTEAGYALYTRAKRLLAEMEDTCREIGEFESNVTGTLSIGTSSVCMSLITGPLSRFHQDYPGVYIKIGHGDTHYLEELLHQNKVDLALLLLPVDDKSYHTIELEEIPFVVVLPCEWADRHPSGEITLQEVASYDLLLARRTEGLGIYETVIRKFQEQHLNPRVVLDCPEISTILSLVSTGMGITIIPDAGLGQEYGDRFRTLSIKEPFSFTRPVVVWRKDHYLSNAARKLIEHLQAGAGSTKKTAPE
>NZ_CP045298.1|WP_152380220.1|2704926_2706111_+|response-regulator
MNILIADDESMIRQGIRRTIGQALPTCGIHLAASTEEAAGILAEHSVDIVLTDILMPGMDGLEFMRISKRKHPHLQWVVISAHSDFQYAQRAVKLGAKDYLLKPIGKRKLLECINVLAAEALVASQQANEGRLLKSNMVYLREAVFQRYALGLDTGKLDIQPFIENYPEFHLFMVRMEPDHKQTHLEHFMIENVLSELIEAGGSGFVVSLDRHSLLGIARLRDEAEAARLETLLESHLKRYVKVPLQITRSGVHHNFASIPEEVARLRRTPEEIAAAAADIGECLRKGMHTVDVALQYIQAHFTEELSLEKVASVVFLNPVYFSQLFKQKTGQGYKDYVICLRMEEAKRLLSDPHLRLADISERIGYQNMRHFTQVFRRKCGMTPTEYRHQRVK
>NZ_CP045298.1|WP_152380219.1|2703148_2704930_+|histidine-kinase
MPRRFQSIQYRLFVLFLLSMSGIVLVVSLLFYNRTTVQFHDKASELARKNVSQTAGLFDLLLGSYNSLSKSISNNMDLVRLLTTDSSDLPAVNYINERTITNILGAIYYSREDLIGIHVITDTGKVYNYGNYMNVIDTQYEHTEWYKEIRKSAGKIAWLGVYPHSAIDQVETRPVFAFGRQLYDLDEHKPIGIVLFEAEPRSVLSALHNLRLGTNSQVYLLGHENRIVSATSSDPPPDLRGLEQQVAEDDVIVNRSNESAVIASKLPFADWSVISVTPSEDLNVELVQNQRYLLIVAPILIIVSALIASIVSRGISLPLKRVIREMNRVETGNFRHTVSIESYEEINQLANSFNHMVRRIAELIELVRISSVSEKNAELHALQTQVNPHFLYNTLDMIYWMLDEKGQDQLGEVVLSLSHMFPYSSHWEEGADVSLREEVEQISHYLTIIQARLEGRVSVDISMDERWLDIRLPKMTLQLLIENAVKHGLEPLPANTGGKLFVRAEEHGGVLSLHIIDNGAGMEYERWEVVQVALAEPGKQTGSGQAGGIGLQNLNLRLRHMFGEEYGLRISSTPGAGTTATVSVPLPQKEEET
>NZ_CP045298.1|WP_152380218.1|2702293_2703118_+|ABC-transporter-permease-subunit
MNTMKKAGVFFLLAMLIVTQLYPLFWLLTYSLKTNEEILSASFFALPVVPQWHNYQEAYEAGNYLRYLGNSVLVTGATMMFVIVLSSMTAYAITRFRWRFGAVVLTLFLIGMMIPLQATLLPLMVMFKNVHILNTYFALILPYIAFQIPIAVFILSGFMRSIPHEIEESAYIDGASIYRIFRSVILPISIPPIMTVCILTCINIWNEYIMAPTFISSEKLKTLPFGVYTFVSQYSVNYGNIGAFLVMGALPVIIIYFVLSEKITKGMVAGAVKG
>NZ_CP045298.1|WP_152380217.1|2699944_2701276_+|extracellular-solute-binding-protein
MGRTEIKAFAVVVVSALALTLAACNNGQSASPGNLGKQGGDTSTQDVTITFQNINPDPSTPSYKMIKQIVSQYEQDHPHVKIELDSLNTDQQKLKLKTQAAAKEVPDITIVNPAAQMKPFVDAGLLAPLDDVADKEGLKNTFQDGLLDYYSFDDKLYAFPDGNNIEVVFYNKELFEQAGILKLPTTFDELITTVKTLKTKGITPIAIGEKDSWTGSLLFMNILLRTNEGPNFLKDVLDGKKTFNDPAFVEAVDAFQELVQAGAFPDGATSIDYNAGCNIFKTGKAAMYIMGTWETGSIDASPVAGKVGAFQFPTVNGKGDVNEYVVAPGSAFAVSANSEHLQETKDFLHYFITEMPKIQFDLKNAIGSGQKIKGDLKEAGYSELAISLYELFKNVKGGDLAFDNTMNPAIAQAHLSSIQNLFVQKENSVQVAKEHQSVFEANK
>NZ_CP045298.1|WP_167518685.1|2699492_2699651_-|hypothetical-protein
MKEVFSKTSLHIDDYLDLLNLAVQVGDTKWQKEITRKLQALSVLQTEQVEID
>NZ_CP045298.1|WP_152382149.1|2715649_2715739_-|transposase
MLEPLLPPARKKQGGRPPKDRRQMLNAVV
>NZ_CP045298.1|WP_152380226.1|2716151_2716670_+|sigma-70-family-RNA-polymerase-sigma-factor
MSIPESSPFRNIFYEYYPTVRRKLAALVRDEAAADDLAQEVFLRLYRNPPDNPATLGAWLHRVLTRIGYDYLEKRARDRKLQNKQEMMYKGEAASESGEETLMRRLDQEEVQAWLDRLPERDRQALLLRYSGYSYAEIAEELNVRPPLIGSLLQRATRKLQATASKAMARQD
>NZ_CP045298.1|WP_152380227.1|2716698_2717805_+|hypothetical-protein
MTTKPQHTEADKSTHEAWERLQQKLATELVNAKWETWDVNNKEDGLKLADTLTPPADLAAIQDSASSLKVEAPAPVASFRRQAGKGRKWATAAAAAVIFGVVLATPVGNNALAAILNQFRVQDIATVDESTLEDMFNQLVPGKSADIENTFGQFTSESGNVRGEFTREQAASKLGYQLLPVNVAGTKESVYVTPSQKITMMLNVDELNKAMQRVGATKLLPESMDDKEIAFSTHEGVNYDLGTDQDHWATLTQMQAPEITVDPSVDTEEAVDAVLQLPILPSNLKEQVKRSRILAGSIPMPYVVNKSAETSEITVEGTKVLVTNMKYSSMTNRTAIWIKDGQFFSFEGGSAYESEADFMHKLKELIEA
>NZ_CP045298.1|WP_152380228.1|2717801_2718785_+|ATP-binding-cassette-domain-containing-protein
MSKSAIDAKGLTKEYSNGRGCRNVTITVGKGEAVGFLGPNGAGKSTFVKMLVGLIHPTAGEATLMSAPIGTLEAKRQIGYLPELYRYQEWLTGDEVVRLHGRLCGLDKQVIDKRVPELLHMVGVGQRGKDRVKHYSKGMQQRLGLACALVNDPAVIFLDEPSSAMDPVGRMHVRNILEELKQQGKTIFLNSHLLEDVEVLCDRMALLNNGQVLRHGRVVEVLQKRVCWRFKVGGFSPFLLSWLMDTTGLSFGVITDGKAEGGFTGETGIDDTVWLEAELESEEQVGWINTLLIGQGMTLYEVTKVRERLEEWFMEAVAGLNHRGEQE
>NZ_CP045298.1|WP_152380229.1|2718781_2719660_+|ABC-transporter-permease-subunit
MRIIWTMTWKELLRKRVLLLTLLLTVVFLLGFWFIAGAIGGDSASRVITGGTDNENMIQEFTLGMFILMLGFFFASFVLAFLAIFSSFSAIAGEAEQGVMQAMLPRPIPRWKWYMGRWLGYVSLGVIYALILYSLILWITDVHASIPRDPVVLVQAFLLFASVVPLLVTVSMFGSGYLSSVANGVVMTMLYGAGWLGGMVGKIIGSVGLEPGPMQTLNNITGVLSLIMPADGLQRKMQAVLFSFENINGLIPVRSGPFGIGEIPSTAFLMYAAFYTAVLFGLGLRRFVRKDL
>NZ_CP045298.1|WP_152380230.1|2720598_2721486_+|NmrA-family-NAD(P)-binding-protein
MNEKKILVLGATGQQGGAAVRHLLADGWEVRAFTRDVSSDRALKLSQLGAELVVGDMDDLAVLDAAMHGVYGIFSVQPPDWNHTTESNADEKRRGKAVADVAQKVNIQHFVYTSVGGAEAQSRFRDAKWEIEQYILSLGLPATILRPATFMENFADPMSAGIQNGTFTQAFKPDGAIPLVAVEDIGAFVALVFRSPDVYLGTTIEIAGDELTPLQIADALGRVTNRTIPYVQIPMESFRQHNEVLASVFEWVSDGGHKVDISIVRKLFPGLMDFDTWVERQGKAKFEALFHTERT
>NZ_CP045298.1|WP_167518686.1|2721724_2721946_+|IS66-family-insertion-sequence-element-accessory-protein-TnpB
MFCNRQRNKLKILLWDHNGFWLLYRRLEKGLFQWPSGNEGTVIISGHELRWLLDGLALEQHKAHSPIRAETII
>NZ_CP045298.1|WP_152380232.1|2723300_2723696_-|hypothetical-protein
MTHSFSSILTYCIQAIAILLIIFNLIKRNKKKIGKGSFSLLLAFLGMAVSFKFGNYILGDHLFSILGLSAWSNNVDNTGFHYTMFLSIIFFIPSLIIGYKNPEEFGVKIGKWVSSIYLFLIIVMFIFFIIS
>NZ_CP045298.1|WP_152380233.1|2723775_2724495_-|hypothetical-protein
MKMKKTSIILTCALALMAVSPVAAFAAPNNVEVSSQAKSDNSLEGLNLISVDKFVQKDAVKTTTYKTADEVFAAHGGTTKRVDLSSLPKNTAVIKVNTVDELDALLSGVSGSLSGEGENVVISPNQSQSNDSNNVSKVSPTAYTSSKSSNLYDAKTWWVRLYSNYTVTNAGIIDVQAYTALSGLTLGVTWNQTSATSTKISSKQWLTKGSGTYNLVIFIEGIGTVYSENVSGSHYVTVS
>NZ_CP045298.1|WP_167518687.1|2725534_2726179_-|S-layer-homology-domain-containing-protein
MKFIDVEGHWAKDAVNDMGSRMVINGVNKEEFNPNADITRSEFAAIIVRGLGLKPEEGQSSFDDVGSEDWYNTYFETAYSNGLIQGFEDGEFRPNDHITREQAMVIIAKAMNITGLQADTSSSSLNNFKDRSSVSEWAEQSVAQCMGAGLVSGRTSTEIAPKANVSRAEAAKLVQALLSKSNLDKPVKKPSSFRKKAFLMYAQQGIIFTMKSGM

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Crispr_ID: NZ_CP045298_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045298_4

3717410-3717965

TypeI-B

Consensus_repeat	Method
CTTTAACCACAACATGAGATGTATTGAAAT	PILER-CR
CTTTAACCACAACATGAGATGTATTGAAAT	CRISPRCasFinder
CTTTAACCACAACATGAGATGTATTGAAAT	CRT

8 spacers

cas8b1,cas7b,cas5,cas3,cas4,cas1,cas2

The CRISPR arrays of NZ_CP045298_4

>merge|NZ_CP045298|4|3717410-3717965|PILER-CR,CRISPRCasFinder,CRT
CTTTAACCACAACATGAGATGTATTGAAATGTTGCTAATATTATAGCATAAGTATGGAGGAAAGTACTTTAACCACAACATGAGATGTATTGAAATCAATGTTGTCGTTTTGGCTATTTAACAAGATGAAAACTTTAACCACAACATGAGATGTATTGAAATAACTGTTACAGTACTTTGTTACTCCGAAGGGCTACCTTTAACCACAGCATGAGATGTATTGAAATCATGTACATACACTTTCGATGGTATGAAGCCCATAGCTTTAACCACAACATGAGATGTATTGAAATAAGCCAGAGAGGGCCAGGTCAGCTCCGCTTTCCTCCCTTTAACCACAACATGAGATGTATTGAAATAGTGCTGGTATATATCCAGCCAATGCCTCGCCAGTACTTTAACCACAACATGAGATGTATTGAAATTCTTTGGCATAGCCATGAACGGCAGACTCCGTTGGGCTTTAACCACAACATGAGATGTATTGAAATGAGCTGTCGCTGCCTCCGCTGATCGTAAACTGTACCTTTAACCACAACATGAGATGTATTGAAAC

>NZ_CP045298|4|3|3717410-3717965|PILER-CR
CTTTAACCACAACATGAGATGTATTGAAAT	GTTGCTAATATTATAGCATAAGTATGGAGGAAAGTA
CTTTAACCACAACATGAGATGTATTGAAAT	CAATGTTGTCGTTTTGGCTATTTAACAAGATGAAAA
CTTTAACCACAACATGAGATGTATTGAAAT	AACTGTTACAGTACTTTGTTACTCCGAAGGGCTAC
CTTTAACCACAGCATGAGATGTATTGAAAT	CATGTACATACACTTTCGATGGTATGAAGCCCATAG
CTTTAACCACAACATGAGATGTATTGAAAT	AAGCCAGAGAGGGCCAGGTCAGCTCCGCTTTCCTCC
CTTTAACCACAACATGAGATGTATTGAAAT	AGTGCTGGTATATATCCAGCCAATGCCTCGCCAGTA
CTTTAACCACAACATGAGATGTATTGAAAT	TCTTTGGCATAGCCATGAACGGCAGACTCCGTTGGG
CTTTAACCACAACATGAGATGTATTGAAAT	GAGCTGTCGCTGCCTCCGCTGATCGTAAACTGTAC
CTTTAACCACAACATGAGATGTATTGAAAC

>NZ_CP045298|4|4|3717410-3717965|CRISPRCasFinder
CTTTAACCACAACATGAGATGTATTGAAAT	GTTGCTAATATTATAGCATAAGTATGGAGGAAAGTA
CTTTAACCACAACATGAGATGTATTGAAAT	CAATGTTGTCGTTTTGGCTATTTAACAAGATGAAAA
CTTTAACCACAACATGAGATGTATTGAAAT	AACTGTTACAGTACTTTGTTACTCCGAAGGGCTAC
CTTTAACCACAGCATGAGATGTATTGAAAT	CATGTACATACACTTTCGATGGTATGAAGCCCATAG
CTTTAACCACAACATGAGATGTATTGAAAT	AAGCCAGAGAGGGCCAGGTCAGCTCCGCTTTCCTCC
CTTTAACCACAACATGAGATGTATTGAAAT	AGTGCTGGTATATATCCAGCCAATGCCTCGCCAGTA
CTTTAACCACAACATGAGATGTATTGAAAT	TCTTTGGCATAGCCATGAACGGCAGACTCCGTTGGG
CTTTAACCACAACATGAGATGTATTGAAAT	GAGCTGTCGCTGCCTCCGCTGATCGTAAACTGTAC
CTTTAACCACAACATGAGATGTATTGAAAC

>NZ_CP045298|4|3|3717410-3717965|CRT
CTTTAACCACAACATGAGATGTATTGAAAT	GTTGCTAATATTATAGCATAAGTATGGAGGAAAGTA
CTTTAACCACAACATGAGATGTATTGAAAT	CAATGTTGTCGTTTTGGCTATTTAACAAGATGAAAA
CTTTAACCACAACATGAGATGTATTGAAAT	AACTGTTACAGTACTTTGTTACTCCGAAGGGCTAC
CTTTAACCACAGCATGAGATGTATTGAAAT	CATGTACATACACTTTCGATGGTATGAAGCCCATAG
CTTTAACCACAACATGAGATGTATTGAAAT	AAGCCAGAGAGGGCCAGGTCAGCTCCGCTTTCCTCC
CTTTAACCACAACATGAGATGTATTGAAAT	AGTGCTGGTATATATCCAGCCAATGCCTCGCCAGTA
CTTTAACCACAACATGAGATGTATTGAAAT	TCTTTGGCATAGCCATGAACGGCAGACTCCGTTGGG
CTTTAACCACAACATGAGATGTATTGAAAT	GAGCTGTCGCTGCCTCCGCTGATCGTAAACTGTAC
CTTTAACCACAACATGAGATGTATTGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045298.1\|WP_167518721.1\|3730412_3730601_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|197775
NZ_CP045298.1\|WP_152380919.1\|3729438_3729720_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP045298.1\|WP_152380916.1\|3723231_3724236_+\|CRISPR-associated-protein	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl\|CDD\|377458
NZ_CP045298.1\|WP_152380915.1\|3721226_3723248_+\|hypothetical-protein	cas8b1	mkCas0106_cas8b1_CAS-I-B	unknown
NZ_CP045298.1\|WP_152380912.1\|3715814_3716522_-\|response-regulator	unknown	unknown	gnl\|CDD\|223816
NZ_CP045298.1\|WP_152382197.1\|3725197_3727909_+\|CRISPR-associated-helicase-Cas3'	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|187770
NZ_CP045298.1\|WP_152380906.1\|3705344_3706568_-\|betaine/proline/choline-family-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226643
NZ_CP045298.1\|WP_152380907.1\|3709512_3711543_-\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|223910
NZ_CP045298.1\|WP_152380918.1\|3728418_3729432_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|187853
NZ_CP045298.1\|WP_152380917.1\|3724270_3725071_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NZ_CP045298.1\|WP_152380913.1\|3718132_3718981_+\|DNA-binding-protein	unknown	unknown	unknown
NZ_CP045298.1\|WP_152380908.1\|3711811_3712759_-\|EamA-family-transporter	unknown	unknown	gnl\|CDD\|307170
NZ_CP045298.1\|WP_152380905.1\|3701462_3702686_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|378925
NZ_CP045298.1\|WP_152380914.1\|3720500_3721205_+\|CRISPR-associated-protein-Cas6	unknown	unknown	gnl\|CDD\|273848
NZ_CP045298.1\|WP_152380909.1\|3713155_3713851_-\|ABC-transporter-permease-subunit	unknown	unknown	unknown
NZ_CP045298.1\|WP_152380910.1\|3713843_3714767_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|213235
NZ_CP045298.1\|WP_025721148.1\|3707083_3707647_+\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|224427
NZ_CP045298.1\|WP_152382196.1\|3707843_3709325_+\|carboxylesterase-family-protein	unknown	unknown	gnl\|CDD\|225181
NZ_CP045298.1\|WP_007429323.1\|3727905_3728400_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NZ_CP045298.1\|WP_152380911.1\|3714868_3715813_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|340423

Protein	Function_ID	Function_description	E-value
NZ_CP045298.1\|WP_167518721.1\|3730412_3730601_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	0.00023024
NZ_CP045298.1\|WP_152380919.1\|3729438_3729720_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.95413e-27
NZ_CP045298.1\|WP_152380916.1\|3723231_3724236_+\|CRISPR-associated-protein	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	6.98517e-34
NZ_CP045298.1\|WP_152380912.1\|3715814_3716522_-\|response-regulator	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	4.28755e-85
NZ_CP045298.1\|WP_152382197.1\|3725197_3727909_+\|CRISPR-associated-helicase-Cas3'	gnl\|CDD\|187770	cd09639, Cas3_I, CRISPR/Cas system-associated protein Cas3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; DEAD/DEAH box helicase DNA helicase cas3'; Often but not always is fused to HD nuclease domain; signature gene for Type I.	7.37047e-30
NZ_CP045298.1\|WP_152380906.1\|3705344_3706568_-\|betaine/proline/choline-family-ABC-transporter-ATP-binding-protein	gnl\|CDD\|226643	COG4175, ProV, ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism].	0
NZ_CP045298.1\|WP_152380910.1\|3713843_3714767_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|213235	cd03268, ABC_BcrA_bacitracin_resist, ATP-binding cassette domain of the bacitracin-resistance transporter. The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.	6.24488e-95
NZ_CP045298.1\|WP_152380918.1\|3728418_3729432_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187853	cd09722, Cas1_I-B, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	6.01599e-132
NZ_CP045298.1\|WP_152380917.1\|3724270_3725071_+\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	9.23748e-38
NZ_CP045298.1\|WP_152380908.1\|3711811_3712759_-\|EamA-family-transporter	gnl\|CDD\|307170	pfam00892, EamA, EamA-like transporter family. This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region. The family used to be known as DUF6. Members of this family usually carry 5+5 transmembrane domains, and this domain attempts to model five of these.	1.65759e-08
NZ_CP045298.1\|WP_152380905.1\|3701462_3702686_+\|ABC-transporter-permease	gnl\|CDD\|378925	pfam12698, ABC2_membrane_3, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family pfam01061.	7.78776e-33
NZ_CP045298.1\|WP_152380914.1\|3720500_3721205_+\|CRISPR-associated-protein-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	1.23237e-07
NZ_CP045298.1\|WP_152382196.1\|3707843_3709325_+\|carboxylesterase-family-protein	gnl\|CDD\|225181	COG2272, PnbA, Carboxylesterase type B [Lipid metabolism].	1.38534e-156
NZ_CP045298.1\|WP_152380907.1\|3709512_3711543_-\|HAMP-domain-containing-protein	gnl\|CDD\|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	4.78275e-57
NZ_CP045298.1\|WP_025721148.1\|3707083_3707647_+\|transcriptional-regulator	gnl\|CDD\|224427	COG1510, COG1510, Predicted transcriptional regulators [Transcription].	6.04672e-43
NZ_CP045298.1\|WP_007429323.1\|3727905_3728400_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	3.31109e-52
NZ_CP045298.1\|WP_152380911.1\|3714868_3715813_-\|sensor-histidine-kinase	gnl\|CDD\|340423	cd16947, HATPase_YcbM-like, Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM. This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).	2.78895e-60

>NZ_CP045298.1|WP_152380912.1|3715814_3716522_-|response-regulator
MNPHILLIEDDTAIAEMMLKALTKEGYKLTTASDGVEGLLAFACHTYDLVLVDLMMPKVDGMEVIRRIRTSSAVPILIMSAKDSDVDKALGLGFGADDYVAKPFSMLEMTARIQSAIRRSTTYARQQRQEEQPKAQILSYGNLHIDFDHFTVIRNKNEIQLTAKESDILKLFVTNPNRVFTKAQLYGFIWKEDYMGDENVINVHIRRLREKIEEDPSHPIHIKTLWGIGYKWENG
>NZ_CP045298.1|WP_152380911.1|3714868_3715813_-|sensor-histidine-kinase
MNIENLSEWIVVVVLTVIILWLWRERMAYKRSIKDVRTLLERIVTVNHAEKLLYVTGDAELQRLMTEINRLLNLNLRVSADYNRSQIAMRKMISNISHDLKTPLTVVLGYAEMLDGDPNISPEERTKLLSRIHQKTNEAIELIGSFFSLAKLEAHDTDIPLTRLEVGELCRRSILDFYDLLTAQGFAVHIDVPEHPVHALGNEGAIGRVLNNLISNAIRYGADGYTLGLTLSEQQDTVRIEVWDRGKGIQEPEQDKVFERMYTLEDSRNKAVQGSGLGLTIAKRLVEAMNGEIQLTSRPYEQTVFSFTLRKISY
>NZ_CP045298.1|WP_152380910.1|3713843_3714767_-|ATP-binding-cassette-domain-containing-protein
MTYILRTHQLTKALKGNEIVAGVSMNVRKGETYGFLGPNGAGKTTMMKMITNLLKPTSGEIELFGEKLTPKSYHLLGRMGSIIEYPIFYDRLTAQQNLELHCEYMGYYNKQAVRDALELVNLRNAGDKPVKDFSLGMKQRLGIARAIATKPELLILDEPINGLDPVGIKEIRQLFHMLCKEYGMTLLVSSHILAEIEQIADTVGVINHGRLIEEVTMEQVRENNTEYIEFTTNDCKKAVYVLSHHLDLNNIRVLNEQSVRIYDTSVPQKQITKTLIINDVEVDSIHQKNSTLEDYFLRLLNGGDLHA
>NZ_CP045298.1|WP_152380909.1|3713155_3713851_-|ABC-transporter-permease-subunit
MLKLMQLELKKFHLAGYIRSALIANVCILGLTCLIAHDTQSEGIHEFAQYTQILDLIDNLVRATFIVFASVLLCRFIVGEFKTKSITILFMYPIHRKKLMIAKLLVVLLFTFLSIIVSEIVLTAAIHLLNQFVVIVPDQLTLAVLGQQSARTLMNAVAASFMGLVPLYMGMRKYSVPTTIVTSILIVALLFSNNNGFILSSIAPVQIGFSVLGMLVAYAAIRRIEYKDITS
>NZ_CP045298.1|WP_152380908.1|3711811_3712759_-|EamA-family-transporter
MSQSTTVLTSKGFDRSSHMKSGFWLVAIGAALWGADPLFRIILLKSFTSAQIVLMEHVLLFIALAPILWKHREEIKAVRLRQVLAILFVSWGGSALASVIFTMALSNGDLNAVLLLQKLQPLVAIILARIILKEMLPRHFGILIVIALLGTYLLTFGWSLPFGHVHDFVHVGSLLALGAAVLWGGSTVMGSYLLRSMKYETVTSLRFMVALPLLIVLTSVEHAPWNMPAGTWAGAAVIINLLLQALLPGLLSLLLYYKGLSTTKASYATMAELSFPMVGVVINWIAFQQIVTVAQLTGFMLIWITLFMISRQQKN
>NZ_CP045298.1|WP_152380907.1|3709512_3711543_-|HAMP-domain-containing-protein
MTNAKQTIPWWSRFLRSFYLMRTKLMVSFLAVLLIPSILIGYFSYQGATTQLTQQVAGSVYTNLYLIRSNVNQYVTPIMKDVDVLATEIKSDSIASDEDALQKKLNVIVKAHPELDAALLGNTKGQYIRTPNKKEADYDPRERKWYKNAMQEKGKVFVSVPAVSVTTGNLVVNLSRTLEDGQGAISLALNLDKMRQNLQSVKIGERGGLFIVDSNHKVVSGAGAAFNNSGKKPTDTIEGLPEVEKNAENDTPSISQIKFMNRDVLAFTLKDPVTGWNIVALSDLEDYSDAARPILKQSLIVIVISVLIAAIIIALMIRSFLIPLRKLQAGTRIVRDGNLTERVNLSSKDEFGELAQNFDQMTHALHTMVSEVNQTSSRLASSSLMIKESTEQTTESVQHVAETVMESAENAATSAEASEQTANAVEEMAKGVSTIAESASSIVDSAGHTEDDVAQGSKMISNVRTQMDRILEAVSQTASLMDELSQLSDDAKQMNSAIAAIAKQTNLLSLNASIEASRAGEAGRGFAVVAVEVRKLSEQSKESADSISQIITQMLDLIQRSTATMNGNVRSQVGEGLRISQDAESAFANIERSTSHIVEQIQSVSAAAEEISASTEEVSATVTHLASLSRSSADSSQTTSAAAQEQMAAMEEIASSSQELSRMAQDLQELVKRFKI
>NZ_CP045298.1|WP_152382196.1|3707843_3709325_+|carboxylesterase-family-protein
MESIIVHTRLGQLRGESGNGYHVWKGIPYAQPPVGALRFHAPQPLKAWKDVRAATRFGPICPQPLPSADSMAGNLVEPPEQSEDCLYLNVWAPASEAPVEGRPVMVWIHGGAFVTGSGIIPLYDGARMAQKGDVVVVTMNYRLGPLGFLHLTPRGEGLTSNAGLLDQIAALEWIRDHIAAFGGNPNEVTVFGESSGAMSIAALLAMPAAEGLFQRAVLQSGASQVLPTSQAEQVTAMYLQQLGVDTQHPERLFTLPTDALMLAMAKTHEVLRPGMAMIYQPVVDGVTLPDVPLSAIAQGSAKQVSVLIGTNLHEGDYFIRKESHLMDKTAASQALEMMTGMPDAAELTEPFPVTIEDQAQMLTDLIFWRPALALAAAQSAYAPVWMYRFDWTFQGHPTFRKAVHGAEIAFVFDNLELLGKLGLDIQPSMRTLAHDMQQAWVTFARIGKPVLPEREWPTYDREERATAIFHQDITVEHDPQGNKRRQLTGQMNI
>NZ_CP045298.1|WP_025721148.1|3707083_3707647_+|transcriptional-regulator
MSLYQLGDEQQASLQKIRKRVIEAIGKNMDLYGITLSAGHLYGLLFFADKPMTLDEMGREMEMSKTSMSTGVRTLLDLKMVNKVWSKGSRKDLYEVEYDWYQTFTDFFAIKWRKAVETNLLVLRKAIDELDRLIAQGGEYAEFKAILQQDRLKMKQAVAYYKWLDRLIDSLESEEIYKLIPKEEVQE
>NZ_CP045298.1|WP_152380906.1|3705344_3706568_-|betaine/proline/choline-family-ABC-transporter-ATP-binding-protein
MTILEVKNVSKLFGPHAEQGVALLEQGWGKERLAKEKQITVGVNRANMEIKQGEIFVIMGLSGSGKSTLVRMLNRLIEPTSGEILVHGKDLRKMNKEQLREVRRKTISMVFQKFALFPHRTVLENVEYGLEIQKVDKARRQEKAQQALELVGLKNWGDKMPDELSGGMQQRVGLARALANDPEVLLMDEAFSALDPLIRRDMQDELLELQDKMKKTIVFITHDLDEALRIGDRIALMRDGAVVQIGTPEEIMIQPANSYVARFVEDVDLSKVLTAAHVMLRPETITMDRGPRVALELMRERGISNLFVIDRAKKLLGVINAEDAVHALRNHLKIEDILMTDGPQVAADNVINDLFEITSSSKVPLAVVDDKQKLLGVIVRGALLGALSGDVHTTKEVNAHDTETANR
>NZ_CP045298.1|WP_152380905.1|3701462_3702686_+|ABC-transporter-permease
MQDQQERLRIRDVFREEWLSIFRDRRFMAILLITPIVYTILFGFLYSHQRITEMPVTVYDGDNSQLSRQIIQAFDATDSFAVTLQATNQEDAVRQVETGEAKVGIVIPDNFTTRLKHGENPPVLTLIDGSNMMYSNSASRIANQVISSVSAGVSINSMKQKGMNADQAASTLSTIPFRSRVLFNPVYDYKLFMPLGVISAALQQCLLLGIALSCTRDKEAGTWGRFGVWKNTPWRLAIAKLAPYYAAGAFNVLTVFSISALCFDIPFRGQVLPLIMVSLAFNFALCGLGFLFSLFSKTRVDATQTLMLIAVPSFMLSGYTWPLEAMPGFLRGLAEILPLTYYLDAVRNITLKGLDISYVFKDTIALGVIGCVSLLVSFAIYPLFFRQHQTVGQQADVPTQESFTFKG
>NZ_CP045298.1|WP_152380913.1|3718132_3718981_+|DNA-binding-protein
MKAFDFDEVTDLDSIVGMLKMAFSLEEWEQMIQIADQLHTQAHRVYEQQQLELTKGGQPRTLHIKRPLVYYLGFSQLTKGIAFQKQGKYESSRECVEKYAELGWVEGLNEEGLQEVEDYRTLAKANTYTLDLLQGKEEVLPNYVRFLHENSSEELLPGMITILESTIVHNYNINGILREFKTRLTELGTFYEEPENIRYYVTYLYLLAVYRFIEEKYTVAIEVTLNALESADKKCVALFESFRSYANKYQKKKYKFIQKNVLERELKNEKNLLYDGYRIRIV
>NZ_CP045298.1|WP_152380914.1|3720500_3721205_+|CRISPR-associated-protein-Cas6
MYFEIHVTTLIKQFSHHLEIPERIGAWIGRAGLNDETLKQTHYDKDYKHYTFGSPFPREKAGVYKQGRVYVITIRSSIEITLRRISAALQALQEDEYFQFIAASPVQSKKLVHITELTTVTPAIVTIEGKPWVPGLSVELLLQRIHANAEKKYNHLYPDQPVRLEQPFIEGIQVLNHKPIALAYKGRKLLGNKLRLLVREDEYSQKLASVVLGSGAAEKNSILGAGFCIAKGLE
>NZ_CP045298.1|WP_152380915.1|3721226_3723248_+|hypothetical-protein
MLKDLTNSYLLAKKEFPNITFDRHRPKEGLYIRLRLDQSWNEQVSQFDSEYMIITKEEPDLTHNKLFEWFQQKDYVSSLISMNKAVDPGKQLHSNNPYTLYAKRDVFLAETQADGTTAMQAHVARFLDKTQATEVQKKWDELIGVKKTGSTSSTQQFFSQTDYAPALEYLVSEERRTSIAQIEQWYATNLSAFIDHIRTIPFKNYVKIFFTPESISLNSSNNNLFNESSSLYSWDEIYGYEYLLYTIPKIFNSNDYNQMVDGALTGLPGFNMSMNSKKPYLEHKTMRVGAPVRLSLEEALRVKEATEWLISQPKFRMNKFSYYTDFSKSISDAAEGYFFVYVEGKDNEIQDYENVPFSKQVYVNIRLKNALGLMTKNNDGEAFMKDYGYLENVEQLQKEISRRFFRGRMNGDFLQDEPKAREKDFTSGMVALFMQSKKGFHDWFFKGTTATIRSQFARVTLRLLEEQLLRVEPAGQEKSKLDLSGLADAMNVRLSLMAHLEGEEYTAMGNRLIAVSNKLKEKLDTLDKRKQKENAHGAGQTEQTANPEPVYVETDDEFYYLAGQLAFYLKSQSEAQQKKGDLLGPFFMAKRSGQLKRRIEEAYHLHRHKILLQYTKLNWALANVNAYQPDKEFQHEDAREMFLAGLFSDNWFWKKGENEKPSSEGENGHGEEN
>NZ_CP045298.1|WP_152380916.1|3723231_3724236_+|CRISPR-associated-protein
MAKKTNRVVGLIGIVSRMANWNADFSGQPKTTSTGQIFGSDKALKYSIKRLWAEEGQKVLYIRSYKVSSGKDKKVDKAKDADKGKEEKLQPRNLAERYEYLFGEEVSKNSREVLSKLFQCVDVMNFGATFAVKDQNIGLAGPVQIGQGFNKFDWSNLEVQDILSPFRNSNEKSEDNDATSIGKKRTVDESHYVYPFSVNPKHYDHYVELLAAGGFEGYTEEAYQAFKTGALTGATLQNTNSKSGAENAFALFVEFKAGSPAYLPNLDPYVKVDKDKDGEQTVYDLSALAPLLNDVNEEIETVELYVNPYASRVELDFPGLRTFNIFTRSELPQG
>NZ_CP045298.1|WP_152380917.1|3724270_3725071_+|type-I-B-CRISPR-associated-protein-Cas5
MQALRFELSGETAFFKKPDVNVYAYFTYSHIHKVALYGLLGAVLGLGGYTQQYERNMALGGKAKQDNPAMPYPEFYEVFRDASVSIVPHGDRGYFSKKIQIFNNTVGYASQEEGGVLNVREQWLERPRWTIYVADDGGVDREVFDRLADYVQHSKAEYIPYLGKNDHPATISKARLVELEPVDEPEYIDSLRAAHLSADVGGYVKDDQMQSYLQEYLPVGLNAANNGYILEPLVFSNQEIDTDELKAEDLQKMYRDADNGRTLYFI
>NZ_CP045298.1|WP_152382197.1|3725197_3727909_+|CRISPR-associated-helicase-Cas3'
MPIHVSIQHWLTEEGKGRLKAHTAIEEGLQQDEMLEEHSDLVMHHAEILMRDHGVEAAVHRALDRLGIDGEPLDESLRQMIMYYFRQAIYLHDLGKVNPAFQRIKMKNNEVKRNAELGDSNHSMLSAVLYLHIHLRQVQEWHDTTELYPNRKKHKRKVLAFLHHLLYSFAYTISRHHTYLGNMDEDMGGQINEFELKIRNQYNRIKENPDYIRYYRDQQDLLQNDNVFGCIRLEGNKRQNKIHRPFPFYVLVKLLYSTMVASDFRATYQYIEQQVPEMHYFGERLPVEPMLEAYRQTGIVRGIESYRQNPDASGLSEMNQLRAALFIETERRLLERLQEPVFYLEAPTGSGKTNMSINLALHLLNSGLGLNKLIYVFPFNSLIEQARQTLNGIFHKEQVNGYRVEVMNSITPMVTEEELEAEATLEGKDKEPDNTDFKRVLLERQLLQYPVTLTSHVNFFNYLFGTGREVNLAFAHLCNSVIVLDEIQSYRNELWKEMIHFLRSFADILNIKIIIMSATLPNLDLLLEQRDHEEAIQTYTLVQNRDRYFIHSLFRERVNLDFNLLKQGKMQPEQVLEHVESVIKRRKRDGQGNRVLIEFIKKKTARQFYNLVLEQDTDIDVYELTGDDSFSYRQELLQKLGKDEHGRFYMSDVIVVATQVIEAGVDIDMDVGFKDISLLDSEEQFLGRLNRSCLRDYCQAYFFNCDEASSVYKNDLRVAFDLKEEAYQKMLENKDFSGFYENVIREINKSREKPDKQHWSDFTKKVQELEFPDVQEHMNLIPDQSVTLFLNYTCPMKDAPPLNGQDVWDEFVRLSDKRLEMDYSERMIRLSLVRAQMNNFTFIYPVPHMYAKWGKVKPGIHTRCIGTLYFVEHGEQYMDMDERTNTKKFNRARYEEAEKRLLL
>NZ_CP045298.1|WP_007429323.1|3727905_3728400_+|CRISPR-associated-protein-Cas4
MRITGTMVNYYVHCRRQCWLFANGMNFEDDSEDVRIGKVMHELQSEGKKNREVAIEGIKVDKLTSDYVTEIKKSDADVEATKWQTLYYMYVLKQKGMERKGKIQFSERNKQASKTIELELDEAAEQAMEQLLAELEQYLQQEQPDPAIREKKCTRCAYLAYCFL
>NZ_CP045298.1|WP_152380918.1|3728418_3729432_+|type-I-B-CRISPR-associated-endonuclease-Cas1
MSKTAPSTRYIRTPGTLGREDNSLTFRSEEKGIIHLPIHGLKELYLLNEITLNSKLLSFLSMAGITVHFFDYYGHFRGTFYPKDARVSGKVKLLQAKACLERRIPIAAAFIGAIAANIHEVLYHYYKHGNKEIKPYLDWLKKDVPGLLDKMEDIPRLLSVEGEIWRRFYDTFKTFLPEDFKMNKRVKRPPDNPLNALISFGNTILYTKTISQIYHTHLDQSISFLHEPSDRRFSLSLDLSEPFKPLLVYRTIFELVNNRRIQVNKHFEKDYNYCILNGTGRDVFITALEDRMKQVFDHGTLKRKVSYLSAIKYDAYKLKKHIVEGTPFVPFLEKEKR
>NZ_CP045298.1|WP_152380919.1|3729438_3729720_+|CRISPR-associated-endonuclease-Cas2
MAKNYNYVILVYDIGEKRVGKVFKICKKYLVHFQKSVFRGEITPANLIQLRAELKKVIDEGTDFVAVFKMTGDYVFDEEIIGVRLNDSESLLL
>NZ_CP045298.1|WP_167518721.1|3730412_3730601_+|helix-turn-helix-domain-containing-protein
MPTDNKKSHTTKPRKQRKVKEEVTLSKIRELMLQRPGIKQKELAEILGISQSRVSQLKNKLN

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Crispr_ID: NZ_CP045298_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045298_5

3719762-3720251

TypeI-B

Consensus_repeat	Method
CTTTAACCACAACATGAGATGTATTGAAAT	PILER-CR
CTTTAACCACAACATGAGATGTATTGAAAT	CRISPRCasFinder
CTTTAACCACAACATGAGATGTATTGAAAT	CRT

7 spacers

cas8b1,cas7b,cas5,cas3,cas4,cas1,cas2

The CRISPR arrays of NZ_CP045298_5

>merge|NZ_CP045298|5|3719762-3720251|PILER-CR,CRISPRCasFinder,CRT
CTTTAACCACAACATGAGATGTATTGAAATATGCCTTTCTGTGAGACTGGCATCACCTGTTCGTTGCTTTAACCACAACATGAGATGTATTGAAATGGTTGCGAAAACGGAAGAAAACAGGGTATTTTCTTCCTTTAACCACAACATGAGATGTATTGAAATCATATACAGTCCCACATGCCGCCGCTTTGCCTACCTCTTTAACCACAACATGAGATGTATTGAAATTTTATGCGTGGATCAGGAAAGAATGTCGCCAGATCCTTTAACCACAACATGAGATGTATTGAAATAGGAAGTTCGAGTGCTCAACCGAGTCAGGGTACAACCTTTAACCACAACATGAGATGTATTGAAATGTTGCAGAACAGCATCCACCAATGAACCGTCATGTGCTTTAACCACAACATGAGATGTATTGAAATTAGTTGATCGTCCTAGCTTCTCTGGCGGCTTCATTCTTTAACCACAGCATGAAATGTACTCAGTC

>NZ_CP045298|5|4|3719762-3720186|PILER-CR
CTTTAACCACAACATGAGATGTATTGAAAT	ATGCCTTTCTGTGAGACTGGCATCACCTGTTCGTTG
CTTTAACCACAACATGAGATGTATTGAAAT	GGTTGCGAAAACGGAAGAAAACAGGGTATTTTCTTC
CTTTAACCACAACATGAGATGTATTGAAAT	CATATACAGTCCCACATGCCGCCGCTTTGCCTACCT
CTTTAACCACAACATGAGATGTATTGAAAT	TTTATGCGTGGATCAGGAAAGAATGTCGCCAGATC
CTTTAACCACAACATGAGATGTATTGAAAT	AGGAAGTTCGAGTGCTCAACCGAGTCAGGGTACAAC
CTTTAACCACAACATGAGATGTATTGAAAT	GTTGCAGAACAGCATCCACCAATGAACCGTCATGTG
CTTTAACCACAACATGAGATGTATTGAAAT

>NZ_CP045298|5|5|3719762-3720251|CRISPRCasFinder
CTTTAACCACAACATGAGATGTATTGAAAT	ATGCCTTTCTGTGAGACTGGCATCACCTGTTCGTTG
CTTTAACCACAACATGAGATGTATTGAAAT	GGTTGCGAAAACGGAAGAAAACAGGGTATTTTCTTC
CTTTAACCACAACATGAGATGTATTGAAAT	CATATACAGTCCCACATGCCGCCGCTTTGCCTACCT
CTTTAACCACAACATGAGATGTATTGAAAT	TTTATGCGTGGATCAGGAAAGAATGTCGCCAGATC
CTTTAACCACAACATGAGATGTATTGAAAT	AGGAAGTTCGAGTGCTCAACCGAGTCAGGGTACAAC
CTTTAACCACAACATGAGATGTATTGAAAT	GTTGCAGAACAGCATCCACCAATGAACCGTCATGTG
CTTTAACCACAACATGAGATGTATTGAAAT	TAGTTGATCGTCCTAGCTTCTCTGGCGGCTTCATT
CTTTAACCACAGCATGAAATGTACTCAGTC

>NZ_CP045298|5|4|3719762-3720251|CRT
CTTTAACCACAACATGAGATGTATTGAAAT	ATGCCTTTCTGTGAGACTGGCATCACCTGTTCGTTG
CTTTAACCACAACATGAGATGTATTGAAAT	GGTTGCGAAAACGGAAGAAAACAGGGTATTTTCTTC
CTTTAACCACAACATGAGATGTATTGAAAT	CATATACAGTCCCACATGCCGCCGCTTTGCCTACCT
CTTTAACCACAACATGAGATGTATTGAAAT	TTTATGCGTGGATCAGGAAAGAATGTCGCCAGATC
CTTTAACCACAACATGAGATGTATTGAAAT	AGGAAGTTCGAGTGCTCAACCGAGTCAGGGTACAAC
CTTTAACCACAACATGAGATGTATTGAAAT	GTTGCAGAACAGCATCCACCAATGAACCGTCATGTG
CTTTAACCACAACATGAGATGTATTGAAAT	TAGTTGATCGTCCTAGCTTCTCTGGCGGCTTCATT
CTTTAACCACAGCATGAAATGTACTCAGTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045298.1\|WP_167518721.1\|3730412_3730601_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|197775
NZ_CP045298.1\|WP_152380919.1\|3729438_3729720_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP045298.1\|WP_152380916.1\|3723231_3724236_+\|CRISPR-associated-protein	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl\|CDD\|377458
NZ_CP045298.1\|WP_152380915.1\|3721226_3723248_+\|hypothetical-protein	cas8b1	mkCas0106_cas8b1_CAS-I-B	unknown
NZ_CP045298.1\|WP_152380912.1\|3715814_3716522_-\|response-regulator	unknown	unknown	gnl\|CDD\|223816
NZ_CP045298.1\|WP_152382197.1\|3725197_3727909_+\|CRISPR-associated-helicase-Cas3'	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|187770
NZ_CP045298.1\|WP_152380906.1\|3705344_3706568_-\|betaine/proline/choline-family-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226643
NZ_CP045298.1\|WP_152380907.1\|3709512_3711543_-\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|223910
NZ_CP045298.1\|WP_152380918.1\|3728418_3729432_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|187853
NZ_CP045298.1\|WP_152380921.1\|3731053_3732133_-\|alcohol-dehydrogenase-catalytic-domain-containing-protein	unknown	unknown	gnl\|CDD\|223992
NZ_CP045298.1\|WP_152380913.1\|3718132_3718981_+\|DNA-binding-protein	unknown	unknown	unknown
NZ_CP045298.1\|WP_152380908.1\|3711811_3712759_-\|EamA-family-transporter	unknown	unknown	gnl\|CDD\|307170
NZ_CP045298.1\|WP_152380917.1\|3724270_3725071_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NZ_CP045298.1\|WP_152380914.1\|3720500_3721205_+\|CRISPR-associated-protein-Cas6	unknown	unknown	gnl\|CDD\|273848
NZ_CP045298.1\|WP_152380909.1\|3713155_3713851_-\|ABC-transporter-permease-subunit	unknown	unknown	unknown
NZ_CP045298.1\|WP_152380910.1\|3713843_3714767_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|213235
NZ_CP045298.1\|WP_025721148.1\|3707083_3707647_+\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|224427
NZ_CP045298.1\|WP_152382196.1\|3707843_3709325_+\|carboxylesterase-family-protein	unknown	unknown	gnl\|CDD\|225181
NZ_CP045298.1\|WP_007429323.1\|3727905_3728400_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NZ_CP045298.1\|WP_152380911.1\|3714868_3715813_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|340423

Protein	Function_ID	Function_description	E-value
NZ_CP045298.1\|WP_167518721.1\|3730412_3730601_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	0.00023024
NZ_CP045298.1\|WP_152380919.1\|3729438_3729720_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.95413e-27
NZ_CP045298.1\|WP_152380916.1\|3723231_3724236_+\|CRISPR-associated-protein	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	6.98517e-34
NZ_CP045298.1\|WP_152380912.1\|3715814_3716522_-\|response-regulator	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	4.28755e-85
NZ_CP045298.1\|WP_152382197.1\|3725197_3727909_+\|CRISPR-associated-helicase-Cas3'	gnl\|CDD\|187770	cd09639, Cas3_I, CRISPR/Cas system-associated protein Cas3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; DEAD/DEAH box helicase DNA helicase cas3'; Often but not always is fused to HD nuclease domain; signature gene for Type I.	7.37047e-30
NZ_CP045298.1\|WP_152380906.1\|3705344_3706568_-\|betaine/proline/choline-family-ABC-transporter-ATP-binding-protein	gnl\|CDD\|226643	COG4175, ProV, ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism].	0
NZ_CP045298.1\|WP_152380910.1\|3713843_3714767_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|213235	cd03268, ABC_BcrA_bacitracin_resist, ATP-binding cassette domain of the bacitracin-resistance transporter. The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.	6.24488e-95
NZ_CP045298.1\|WP_152380918.1\|3728418_3729432_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187853	cd09722, Cas1_I-B, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	6.01599e-132
NZ_CP045298.1\|WP_152380908.1\|3711811_3712759_-\|EamA-family-transporter	gnl\|CDD\|307170	pfam00892, EamA, EamA-like transporter family. This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region. The family used to be known as DUF6. Members of this family usually carry 5+5 transmembrane domains, and this domain attempts to model five of these.	1.65759e-08
NZ_CP045298.1\|WP_152380917.1\|3724270_3725071_+\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	9.23748e-38
NZ_CP045298.1\|WP_152380914.1\|3720500_3721205_+\|CRISPR-associated-protein-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	1.23237e-07
NZ_CP045298.1\|WP_152382196.1\|3707843_3709325_+\|carboxylesterase-family-protein	gnl\|CDD\|225181	COG2272, PnbA, Carboxylesterase type B [Lipid metabolism].	1.38534e-156
NZ_CP045298.1\|WP_152380907.1\|3709512_3711543_-\|HAMP-domain-containing-protein	gnl\|CDD\|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	4.78275e-57
NZ_CP045298.1\|WP_025721148.1\|3707083_3707647_+\|transcriptional-regulator	gnl\|CDD\|224427	COG1510, COG1510, Predicted transcriptional regulators [Transcription].	6.04672e-43
NZ_CP045298.1\|WP_152380921.1\|3731053_3732133_-\|alcohol-dehydrogenase-catalytic-domain-containing-protein	gnl\|CDD\|223992	COG1064, AdhP, Zn-dependent alcohol dehydrogenases [General function prediction only].	8.52061e-31
NZ_CP045298.1\|WP_007429323.1\|3727905_3728400_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	3.31109e-52
NZ_CP045298.1\|WP_152380911.1\|3714868_3715813_-\|sensor-histidine-kinase	gnl\|CDD\|340423	cd16947, HATPase_YcbM-like, Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM. This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).	2.78895e-60

>NZ_CP045298.1|WP_152380913.1|3718132_3718981_+|DNA-binding-protein
MKAFDFDEVTDLDSIVGMLKMAFSLEEWEQMIQIADQLHTQAHRVYEQQQLELTKGGQPRTLHIKRPLVYYLGFSQLTKGIAFQKQGKYESSRECVEKYAELGWVEGLNEEGLQEVEDYRTLAKANTYTLDLLQGKEEVLPNYVRFLHENSSEELLPGMITILESTIVHNYNINGILREFKTRLTELGTFYEEPENIRYYVTYLYLLAVYRFIEEKYTVAIEVTLNALESADKKCVALFESFRSYANKYQKKKYKFIQKNVLERELKNEKNLLYDGYRIRIV
>NZ_CP045298.1|WP_152380912.1|3715814_3716522_-|response-regulator
MNPHILLIEDDTAIAEMMLKALTKEGYKLTTASDGVEGLLAFACHTYDLVLVDLMMPKVDGMEVIRRIRTSSAVPILIMSAKDSDVDKALGLGFGADDYVAKPFSMLEMTARIQSAIRRSTTYARQQRQEEQPKAQILSYGNLHIDFDHFTVIRNKNEIQLTAKESDILKLFVTNPNRVFTKAQLYGFIWKEDYMGDENVINVHIRRLREKIEEDPSHPIHIKTLWGIGYKWENG
>NZ_CP045298.1|WP_152380911.1|3714868_3715813_-|sensor-histidine-kinase
MNIENLSEWIVVVVLTVIILWLWRERMAYKRSIKDVRTLLERIVTVNHAEKLLYVTGDAELQRLMTEINRLLNLNLRVSADYNRSQIAMRKMISNISHDLKTPLTVVLGYAEMLDGDPNISPEERTKLLSRIHQKTNEAIELIGSFFSLAKLEAHDTDIPLTRLEVGELCRRSILDFYDLLTAQGFAVHIDVPEHPVHALGNEGAIGRVLNNLISNAIRYGADGYTLGLTLSEQQDTVRIEVWDRGKGIQEPEQDKVFERMYTLEDSRNKAVQGSGLGLTIAKRLVEAMNGEIQLTSRPYEQTVFSFTLRKISY
>NZ_CP045298.1|WP_152380910.1|3713843_3714767_-|ATP-binding-cassette-domain-containing-protein
MTYILRTHQLTKALKGNEIVAGVSMNVRKGETYGFLGPNGAGKTTMMKMITNLLKPTSGEIELFGEKLTPKSYHLLGRMGSIIEYPIFYDRLTAQQNLELHCEYMGYYNKQAVRDALELVNLRNAGDKPVKDFSLGMKQRLGIARAIATKPELLILDEPINGLDPVGIKEIRQLFHMLCKEYGMTLLVSSHILAEIEQIADTVGVINHGRLIEEVTMEQVRENNTEYIEFTTNDCKKAVYVLSHHLDLNNIRVLNEQSVRIYDTSVPQKQITKTLIINDVEVDSIHQKNSTLEDYFLRLLNGGDLHA
>NZ_CP045298.1|WP_152380909.1|3713155_3713851_-|ABC-transporter-permease-subunit
MLKLMQLELKKFHLAGYIRSALIANVCILGLTCLIAHDTQSEGIHEFAQYTQILDLIDNLVRATFIVFASVLLCRFIVGEFKTKSITILFMYPIHRKKLMIAKLLVVLLFTFLSIIVSEIVLTAAIHLLNQFVVIVPDQLTLAVLGQQSARTLMNAVAASFMGLVPLYMGMRKYSVPTTIVTSILIVALLFSNNNGFILSSIAPVQIGFSVLGMLVAYAAIRRIEYKDITS
>NZ_CP045298.1|WP_152380908.1|3711811_3712759_-|EamA-family-transporter
MSQSTTVLTSKGFDRSSHMKSGFWLVAIGAALWGADPLFRIILLKSFTSAQIVLMEHVLLFIALAPILWKHREEIKAVRLRQVLAILFVSWGGSALASVIFTMALSNGDLNAVLLLQKLQPLVAIILARIILKEMLPRHFGILIVIALLGTYLLTFGWSLPFGHVHDFVHVGSLLALGAAVLWGGSTVMGSYLLRSMKYETVTSLRFMVALPLLIVLTSVEHAPWNMPAGTWAGAAVIINLLLQALLPGLLSLLLYYKGLSTTKASYATMAELSFPMVGVVINWIAFQQIVTVAQLTGFMLIWITLFMISRQQKN
>NZ_CP045298.1|WP_152380907.1|3709512_3711543_-|HAMP-domain-containing-protein
MTNAKQTIPWWSRFLRSFYLMRTKLMVSFLAVLLIPSILIGYFSYQGATTQLTQQVAGSVYTNLYLIRSNVNQYVTPIMKDVDVLATEIKSDSIASDEDALQKKLNVIVKAHPELDAALLGNTKGQYIRTPNKKEADYDPRERKWYKNAMQEKGKVFVSVPAVSVTTGNLVVNLSRTLEDGQGAISLALNLDKMRQNLQSVKIGERGGLFIVDSNHKVVSGAGAAFNNSGKKPTDTIEGLPEVEKNAENDTPSISQIKFMNRDVLAFTLKDPVTGWNIVALSDLEDYSDAARPILKQSLIVIVISVLIAAIIIALMIRSFLIPLRKLQAGTRIVRDGNLTERVNLSSKDEFGELAQNFDQMTHALHTMVSEVNQTSSRLASSSLMIKESTEQTTESVQHVAETVMESAENAATSAEASEQTANAVEEMAKGVSTIAESASSIVDSAGHTEDDVAQGSKMISNVRTQMDRILEAVSQTASLMDELSQLSDDAKQMNSAIAAIAKQTNLLSLNASIEASRAGEAGRGFAVVAVEVRKLSEQSKESADSISQIITQMLDLIQRSTATMNGNVRSQVGEGLRISQDAESAFANIERSTSHIVEQIQSVSAAAEEISASTEEVSATVTHLASLSRSSADSSQTTSAAAQEQMAAMEEIASSSQELSRMAQDLQELVKRFKI
>NZ_CP045298.1|WP_152382196.1|3707843_3709325_+|carboxylesterase-family-protein
MESIIVHTRLGQLRGESGNGYHVWKGIPYAQPPVGALRFHAPQPLKAWKDVRAATRFGPICPQPLPSADSMAGNLVEPPEQSEDCLYLNVWAPASEAPVEGRPVMVWIHGGAFVTGSGIIPLYDGARMAQKGDVVVVTMNYRLGPLGFLHLTPRGEGLTSNAGLLDQIAALEWIRDHIAAFGGNPNEVTVFGESSGAMSIAALLAMPAAEGLFQRAVLQSGASQVLPTSQAEQVTAMYLQQLGVDTQHPERLFTLPTDALMLAMAKTHEVLRPGMAMIYQPVVDGVTLPDVPLSAIAQGSAKQVSVLIGTNLHEGDYFIRKESHLMDKTAASQALEMMTGMPDAAELTEPFPVTIEDQAQMLTDLIFWRPALALAAAQSAYAPVWMYRFDWTFQGHPTFRKAVHGAEIAFVFDNLELLGKLGLDIQPSMRTLAHDMQQAWVTFARIGKPVLPEREWPTYDREERATAIFHQDITVEHDPQGNKRRQLTGQMNI
>NZ_CP045298.1|WP_025721148.1|3707083_3707647_+|transcriptional-regulator
MSLYQLGDEQQASLQKIRKRVIEAIGKNMDLYGITLSAGHLYGLLFFADKPMTLDEMGREMEMSKTSMSTGVRTLLDLKMVNKVWSKGSRKDLYEVEYDWYQTFTDFFAIKWRKAVETNLLVLRKAIDELDRLIAQGGEYAEFKAILQQDRLKMKQAVAYYKWLDRLIDSLESEEIYKLIPKEEVQE
>NZ_CP045298.1|WP_152380906.1|3705344_3706568_-|betaine/proline/choline-family-ABC-transporter-ATP-binding-protein
MTILEVKNVSKLFGPHAEQGVALLEQGWGKERLAKEKQITVGVNRANMEIKQGEIFVIMGLSGSGKSTLVRMLNRLIEPTSGEILVHGKDLRKMNKEQLREVRRKTISMVFQKFALFPHRTVLENVEYGLEIQKVDKARRQEKAQQALELVGLKNWGDKMPDELSGGMQQRVGLARALANDPEVLLMDEAFSALDPLIRRDMQDELLELQDKMKKTIVFITHDLDEALRIGDRIALMRDGAVVQIGTPEEIMIQPANSYVARFVEDVDLSKVLTAAHVMLRPETITMDRGPRVALELMRERGISNLFVIDRAKKLLGVINAEDAVHALRNHLKIEDILMTDGPQVAADNVINDLFEITSSSKVPLAVVDDKQKLLGVIVRGALLGALSGDVHTTKEVNAHDTETANR
>NZ_CP045298.1|WP_152380914.1|3720500_3721205_+|CRISPR-associated-protein-Cas6
MYFEIHVTTLIKQFSHHLEIPERIGAWIGRAGLNDETLKQTHYDKDYKHYTFGSPFPREKAGVYKQGRVYVITIRSSIEITLRRISAALQALQEDEYFQFIAASPVQSKKLVHITELTTVTPAIVTIEGKPWVPGLSVELLLQRIHANAEKKYNHLYPDQPVRLEQPFIEGIQVLNHKPIALAYKGRKLLGNKLRLLVREDEYSQKLASVVLGSGAAEKNSILGAGFCIAKGLE
>NZ_CP045298.1|WP_152380915.1|3721226_3723248_+|hypothetical-protein
MLKDLTNSYLLAKKEFPNITFDRHRPKEGLYIRLRLDQSWNEQVSQFDSEYMIITKEEPDLTHNKLFEWFQQKDYVSSLISMNKAVDPGKQLHSNNPYTLYAKRDVFLAETQADGTTAMQAHVARFLDKTQATEVQKKWDELIGVKKTGSTSSTQQFFSQTDYAPALEYLVSEERRTSIAQIEQWYATNLSAFIDHIRTIPFKNYVKIFFTPESISLNSSNNNLFNESSSLYSWDEIYGYEYLLYTIPKIFNSNDYNQMVDGALTGLPGFNMSMNSKKPYLEHKTMRVGAPVRLSLEEALRVKEATEWLISQPKFRMNKFSYYTDFSKSISDAAEGYFFVYVEGKDNEIQDYENVPFSKQVYVNIRLKNALGLMTKNNDGEAFMKDYGYLENVEQLQKEISRRFFRGRMNGDFLQDEPKAREKDFTSGMVALFMQSKKGFHDWFFKGTTATIRSQFARVTLRLLEEQLLRVEPAGQEKSKLDLSGLADAMNVRLSLMAHLEGEEYTAMGNRLIAVSNKLKEKLDTLDKRKQKENAHGAGQTEQTANPEPVYVETDDEFYYLAGQLAFYLKSQSEAQQKKGDLLGPFFMAKRSGQLKRRIEEAYHLHRHKILLQYTKLNWALANVNAYQPDKEFQHEDAREMFLAGLFSDNWFWKKGENEKPSSEGENGHGEEN
>NZ_CP045298.1|WP_152380916.1|3723231_3724236_+|CRISPR-associated-protein
MAKKTNRVVGLIGIVSRMANWNADFSGQPKTTSTGQIFGSDKALKYSIKRLWAEEGQKVLYIRSYKVSSGKDKKVDKAKDADKGKEEKLQPRNLAERYEYLFGEEVSKNSREVLSKLFQCVDVMNFGATFAVKDQNIGLAGPVQIGQGFNKFDWSNLEVQDILSPFRNSNEKSEDNDATSIGKKRTVDESHYVYPFSVNPKHYDHYVELLAAGGFEGYTEEAYQAFKTGALTGATLQNTNSKSGAENAFALFVEFKAGSPAYLPNLDPYVKVDKDKDGEQTVYDLSALAPLLNDVNEEIETVELYVNPYASRVELDFPGLRTFNIFTRSELPQG
>NZ_CP045298.1|WP_152380917.1|3724270_3725071_+|type-I-B-CRISPR-associated-protein-Cas5
MQALRFELSGETAFFKKPDVNVYAYFTYSHIHKVALYGLLGAVLGLGGYTQQYERNMALGGKAKQDNPAMPYPEFYEVFRDASVSIVPHGDRGYFSKKIQIFNNTVGYASQEEGGVLNVREQWLERPRWTIYVADDGGVDREVFDRLADYVQHSKAEYIPYLGKNDHPATISKARLVELEPVDEPEYIDSLRAAHLSADVGGYVKDDQMQSYLQEYLPVGLNAANNGYILEPLVFSNQEIDTDELKAEDLQKMYRDADNGRTLYFI
>NZ_CP045298.1|WP_152382197.1|3725197_3727909_+|CRISPR-associated-helicase-Cas3'
MPIHVSIQHWLTEEGKGRLKAHTAIEEGLQQDEMLEEHSDLVMHHAEILMRDHGVEAAVHRALDRLGIDGEPLDESLRQMIMYYFRQAIYLHDLGKVNPAFQRIKMKNNEVKRNAELGDSNHSMLSAVLYLHIHLRQVQEWHDTTELYPNRKKHKRKVLAFLHHLLYSFAYTISRHHTYLGNMDEDMGGQINEFELKIRNQYNRIKENPDYIRYYRDQQDLLQNDNVFGCIRLEGNKRQNKIHRPFPFYVLVKLLYSTMVASDFRATYQYIEQQVPEMHYFGERLPVEPMLEAYRQTGIVRGIESYRQNPDASGLSEMNQLRAALFIETERRLLERLQEPVFYLEAPTGSGKTNMSINLALHLLNSGLGLNKLIYVFPFNSLIEQARQTLNGIFHKEQVNGYRVEVMNSITPMVTEEELEAEATLEGKDKEPDNTDFKRVLLERQLLQYPVTLTSHVNFFNYLFGTGREVNLAFAHLCNSVIVLDEIQSYRNELWKEMIHFLRSFADILNIKIIIMSATLPNLDLLLEQRDHEEAIQTYTLVQNRDRYFIHSLFRERVNLDFNLLKQGKMQPEQVLEHVESVIKRRKRDGQGNRVLIEFIKKKTARQFYNLVLEQDTDIDVYELTGDDSFSYRQELLQKLGKDEHGRFYMSDVIVVATQVIEAGVDIDMDVGFKDISLLDSEEQFLGRLNRSCLRDYCQAYFFNCDEASSVYKNDLRVAFDLKEEAYQKMLENKDFSGFYENVIREINKSREKPDKQHWSDFTKKVQELEFPDVQEHMNLIPDQSVTLFLNYTCPMKDAPPLNGQDVWDEFVRLSDKRLEMDYSERMIRLSLVRAQMNNFTFIYPVPHMYAKWGKVKPGIHTRCIGTLYFVEHGEQYMDMDERTNTKKFNRARYEEAEKRLLL
>NZ_CP045298.1|WP_007429323.1|3727905_3728400_+|CRISPR-associated-protein-Cas4
MRITGTMVNYYVHCRRQCWLFANGMNFEDDSEDVRIGKVMHELQSEGKKNREVAIEGIKVDKLTSDYVTEIKKSDADVEATKWQTLYYMYVLKQKGMERKGKIQFSERNKQASKTIELELDEAAEQAMEQLLAELEQYLQQEQPDPAIREKKCTRCAYLAYCFL
>NZ_CP045298.1|WP_152380918.1|3728418_3729432_+|type-I-B-CRISPR-associated-endonuclease-Cas1
MSKTAPSTRYIRTPGTLGREDNSLTFRSEEKGIIHLPIHGLKELYLLNEITLNSKLLSFLSMAGITVHFFDYYGHFRGTFYPKDARVSGKVKLLQAKACLERRIPIAAAFIGAIAANIHEVLYHYYKHGNKEIKPYLDWLKKDVPGLLDKMEDIPRLLSVEGEIWRRFYDTFKTFLPEDFKMNKRVKRPPDNPLNALISFGNTILYTKTISQIYHTHLDQSISFLHEPSDRRFSLSLDLSEPFKPLLVYRTIFELVNNRRIQVNKHFEKDYNYCILNGTGRDVFITALEDRMKQVFDHGTLKRKVSYLSAIKYDAYKLKKHIVEGTPFVPFLEKEKR
>NZ_CP045298.1|WP_152380919.1|3729438_3729720_+|CRISPR-associated-endonuclease-Cas2
MAKNYNYVILVYDIGEKRVGKVFKICKKYLVHFQKSVFRGEITPANLIQLRAELKKVIDEGTDFVAVFKMTGDYVFDEEIIGVRLNDSESLLL
>NZ_CP045298.1|WP_167518721.1|3730412_3730601_+|helix-turn-helix-domain-containing-protein
MPTDNKKSHTTKPRKQRKVKEEVTLSKIRELMLQRPGIKQKELAEILGISQSRVSQLKNKLN
>NZ_CP045298.1|WP_152380921.1|3731053_3732133_-|alcohol-dehydrogenase-catalytic-domain-containing-protein
MKAAILKQFGMPLAIESLPDPILGTGEVIVDVAAAPVLSYMKEVISGERKYLMLLPQAPGAGAIGRVRAVGPDSTRLAVGDWVYCDPTVRSRDDALTPDITLQGLSARGEGGLHLQKHFRHGSYAQQILIPTENAIRVGSLDNEDAGKWCAFGTLAVPYGGLLKANLQAGETILVSGATGSFGSACIALALAMGAGCVVAPGRNEETLEDLSRRFGSRIRTVKLSGDEDDDRKRMQQAAPGPIDCVLDILPPFAPATAVRAAVMSVRPYGRAVLMGGVGMLGGAGLDLPYPWIMRNCITIHGQWLCPAEAPSRLVALIQSGLIALEQFDITAFDLDHANEAIEHAAANPGPFKLTVIKP

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Crispr_ID: NZ_CP045298_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045298_6

3729897-3730385

TypeI-B

Consensus_repeat	Method
CTTTAACCACAACATGAGATGTATTGAAAT	PILER-CR
CTTTAACCACAACATGAGATGTATTGAAAT	CRISPRCasFinder
CTTTAACCACAACATGAGATGTATTGAAAT	CRT

7 spacers

cas2,cas1,cas4,cas3,cas5,cas7b,cas8b1

The CRISPR arrays of NZ_CP045298_6

>merge|NZ_CP045298|6|3729897-3730385|PILER-CR,CRISPRCasFinder,CRT
CTTTAACCACAACATGAGATGTATTGAAATAGGTATATTTCCATTCGTTCGAGGCCGCCGTTTGCCTTTAACCACAACATGAGATGTATTGAAATAGTGCTGAAAGATTTGAAAGCAAATGGTAAAGAGCCTTTAACCACAACATGAGATGTATTGAAATCGGAATTAAGCGGGGAGGCTGCAATGCTAATCCGCTTTAACCACAACATGAGATGTATTGAAATGCAAGTGGCAGGAAAGACAATTGAGGAAAGACTCACCTTTAACCACAACATGAGATGTATTGAAATTGAATGAAGCCCAGGCCAGCCAGCACCTCCAGCGATCTTTAACCACAACATGAGATGTATTGAAATTTTGGATAGTGTAACTCAGCGTTTAGACGTTCGAAACTTTAACCACAACATGAGATGTATTGAAATTAATGTTTATGGGGGAACCGAAGATTTTATTAAATCTCTTTAACCACAACATGAGTGCATCCAGGGT

>NZ_CP045298|6|5|3729897-3730318|PILER-CR
CTTTAACCACAACATGAGATGTATTGAAAT	AGGTATATTTCCATTCGTTCGAGGCCGCCGTTTGC
CTTTAACCACAACATGAGATGTATTGAAAT	AGTGCTGAAAGATTTGAAAGCAAATGGTAAAGAGC
CTTTAACCACAACATGAGATGTATTGAAAT	CGGAATTAAGCGGGGAGGCTGCAATGCTAATCCG
CTTTAACCACAACATGAGATGTATTGAAAT	GCAAGTGGCAGGAAAGACAATTGAGGAAAGACTCAC
CTTTAACCACAACATGAGATGTATTGAAAT	TGAATGAAGCCCAGGCCAGCCAGCACCTCCAGCGAT
CTTTAACCACAACATGAGATGTATTGAAAT	TTTGGATAGTGTAACTCAGCGTTTAGACGTTCGAAA
CTTTAACCACAACATGAGATGTATTGAAAT

>NZ_CP045298|6|6|3729897-3730318|CRISPRCasFinder
CTTTAACCACAACATGAGATGTATTGAAAT	AGGTATATTTCCATTCGTTCGAGGCCGCCGTTTGC
CTTTAACCACAACATGAGATGTATTGAAAT	AGTGCTGAAAGATTTGAAAGCAAATGGTAAAGAGC
CTTTAACCACAACATGAGATGTATTGAAAT	CGGAATTAAGCGGGGAGGCTGCAATGCTAATCCG
CTTTAACCACAACATGAGATGTATTGAAAT	GCAAGTGGCAGGAAAGACAATTGAGGAAAGACTCAC
CTTTAACCACAACATGAGATGTATTGAAAT	TGAATGAAGCCCAGGCCAGCCAGCACCTCCAGCGAT
CTTTAACCACAACATGAGATGTATTGAAAT	TTTGGATAGTGTAACTCAGCGTTTAGACGTTCGAAA
CTTTAACCACAACATGAGATGTATTGAAAT

>NZ_CP045298|6|5|3729897-3730385|CRT
CTTTAACCACAACATGAGATGTATTGAAAT	AGGTATATTTCCATTCGTTCGAGGCCGCCGTTTGC
CTTTAACCACAACATGAGATGTATTGAAAT	AGTGCTGAAAGATTTGAAAGCAAATGGTAAAGAGC
CTTTAACCACAACATGAGATGTATTGAAAT	CGGAATTAAGCGGGGAGGCTGCAATGCTAATCCG
CTTTAACCACAACATGAGATGTATTGAAAT	GCAAGTGGCAGGAAAGACAATTGAGGAAAGACTCAC
CTTTAACCACAACATGAGATGTATTGAAAT	TGAATGAAGCCCAGGCCAGCCAGCACCTCCAGCGAT
CTTTAACCACAACATGAGATGTATTGAAAT	TTTGGATAGTGTAACTCAGCGTTTAGACGTTCGAAA
CTTTAACCACAACATGAGATGTATTGAAAT	TAATGTTTATGGGGGAACCGAAGATTTTATTAAATCT
CTTTAACCACAACATGAGTGCATCCAGGGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045298.1\|WP_167518721.1\|3730412_3730601_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|197775
NZ_CP045298.1\|WP_152380919.1\|3729438_3729720_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP045298.1\|WP_025718663.1\|3739844_3741041_+\|alanine-racemase	unknown	unknown	gnl\|CDD\|143481
NZ_CP045298.1\|WP_152380915.1\|3721226_3723248_+\|hypothetical-protein	cas8b1	mkCas0106_cas8b1_CAS-I-B	unknown
NZ_CP045298.1\|WP_152380912.1\|3715814_3716522_-\|response-regulator	unknown	unknown	gnl\|CDD\|223816
NZ_CP045298.1\|WP_152382197.1\|3725197_3727909_+\|CRISPR-associated-helicase-Cas3'	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|187770
NZ_CP045298.1\|WP_152380923.1\|3735370_3737002_+\|formate--tetrahydrofolate-ligase	unknown	unknown	gnl\|CDD\|376511
NZ_CP045298.1\|WP_007429334.1\|3741334_3741616_+\|ribbon-helix-helix-protein,-CopG-family	unknown	unknown	gnl\|CDD\|223932
NZ_CP045298.1\|WP_152380922.1\|3732258_3733077_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|375319
NZ_CP045298.1\|WP_152380918.1\|3728418_3729432_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|187853
NZ_CP045298.1\|WP_007429335.1\|3741622_3741973_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	unknown	unknown	gnl\|CDD\|367091
NZ_CP045298.1\|WP_152380913.1\|3718132_3718981_+\|DNA-binding-protein	unknown	unknown	unknown
NZ_CP045298.1\|WP_025718655.1\|3734242_3734746_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045298.1\|WP_152380924.1\|3736937_3737267_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223687
NZ_CP045298.1\|WP_152380917.1\|3724270_3725071_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NZ_CP045298.1\|WP_152380914.1\|3720500_3721205_+\|CRISPR-associated-protein-Cas6	unknown	unknown	gnl\|CDD\|273848
NZ_CP045298.1\|WP_152380916.1\|3723231_3724236_+\|CRISPR-associated-protein	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl\|CDD\|377458
NZ_CP045298.1\|WP_152380921.1\|3731053_3732133_-\|alcohol-dehydrogenase-catalytic-domain-containing-protein	unknown	unknown	gnl\|CDD\|223992
NZ_CP045298.1\|WP_007429323.1\|3727905_3728400_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NZ_CP045298.1\|WP_025718661.1\|3738299_3739574_+\|outer-membrane-lipoprotein-sorting-protein	unknown	unknown	gnl\|CDD\|225390

Protein	Function_ID	Function_description	E-value
NZ_CP045298.1\|WP_167518721.1\|3730412_3730601_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	0.00023024
NZ_CP045298.1\|WP_152380919.1\|3729438_3729720_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.95413e-27
NZ_CP045298.1\|WP_025718663.1\|3739844_3741041_+\|alanine-racemase	gnl\|CDD\|143481	cd00430, PLPDE_III_AR, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase. This family includes predominantly bacterial alanine racemases (AR), some serine racemases (SerRac), and putative bifunctional enzymes containing N-terminal UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase (murF) and C-terminal AR domains. These proteins are fold type III PLP-dependent enzymes that play essential roles in peptidoglycan biosynthesis. AR catalyzes the interconversion between L- and D-alanine, which is an essential component of the peptidoglycan layer of bacterial cell walls. SerRac converts L-serine into its D-enantiomer (D-serine) for peptidoglycan synthesis. murF catalyzes the addition of D-Ala-D-Ala to UDPMurNAc-tripeptide, the final step in the synthesis of the cytoplasmic precursor of bacterial cell wall peptidoglycan. Members of this family contain an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain. They exist as homodimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. AR and other members of this family require dimer formation and the presence of the PLP cofactor for catalytic activity. Fungal ARs and eukaryotic serine racemases, which are fold types I and II PLP-dependent enzymes respectively, are excluded from this family.	1.15263e-178
NZ_CP045298.1\|WP_152380912.1\|3715814_3716522_-\|response-regulator	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	4.28755e-85
NZ_CP045298.1\|WP_152382197.1\|3725197_3727909_+\|CRISPR-associated-helicase-Cas3'	gnl\|CDD\|187770	cd09639, Cas3_I, CRISPR/Cas system-associated protein Cas3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; DEAD/DEAH box helicase DNA helicase cas3'; Often but not always is fused to HD nuclease domain; signature gene for Type I.	7.37047e-30
NZ_CP045298.1\|WP_152380923.1\|3735370_3737002_+\|formate--tetrahydrofolate-ligase	gnl\|CDD\|376511	pfam01268, FTHFS, Formate--tetrahydrofolate ligase.	0
NZ_CP045298.1\|WP_007429334.1\|3741334_3741616_+\|ribbon-helix-helix-protein,-CopG-family	gnl\|CDD\|223932	COG0864, NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain [Transcription].	2.42846e-17
NZ_CP045298.1\|WP_152380922.1\|3732258_3733077_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|375319	pfam17765, MLTR_LBD, MmyB-like transcription regulator ligand binding domain. This domain is found in a family of actinobacterial transcription factors. The structure shows it has a PAS domain like fold and it is bound to Myristic acid.	4.84458e-53
NZ_CP045298.1\|WP_152380918.1\|3728418_3729432_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187853	cd09722, Cas1_I-B, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	6.01599e-132
NZ_CP045298.1\|WP_007429335.1\|3741622_3741973_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	gnl\|CDD\|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	2.5311e-40
NZ_CP045298.1\|WP_025718661.1\|3738299_3739574_+\|outer-membrane-lipoprotein-sorting-protein	gnl\|CDD\|225390	COG2834, LolA, Outer membrane lipoprotein-sorting protein [Cell envelope biogenesis, outer membrane].	7.7836e-30
NZ_CP045298.1\|WP_152380924.1\|3736937_3737267_-\|hypothetical-protein	gnl\|CDD\|223687	COG0614, FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism].	0.00692826
NZ_CP045298.1\|WP_152380917.1\|3724270_3725071_+\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	9.23748e-38
NZ_CP045298.1\|WP_152380914.1\|3720500_3721205_+\|CRISPR-associated-protein-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	1.23237e-07
NZ_CP045298.1\|WP_152380916.1\|3723231_3724236_+\|CRISPR-associated-protein	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	6.98517e-34
NZ_CP045298.1\|WP_152380921.1\|3731053_3732133_-\|alcohol-dehydrogenase-catalytic-domain-containing-protein	gnl\|CDD\|223992	COG1064, AdhP, Zn-dependent alcohol dehydrogenases [General function prediction only].	8.52061e-31
NZ_CP045298.1\|WP_007429323.1\|3727905_3728400_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	3.31109e-52

>NZ_CP045298.1|WP_152380919.1|3729438_3729720_+|CRISPR-associated-endonuclease-Cas2
MAKNYNYVILVYDIGEKRVGKVFKICKKYLVHFQKSVFRGEITPANLIQLRAELKKVIDEGTDFVAVFKMTGDYVFDEEIIGVRLNDSESLLL
>NZ_CP045298.1|WP_152380918.1|3728418_3729432_+|type-I-B-CRISPR-associated-endonuclease-Cas1
MSKTAPSTRYIRTPGTLGREDNSLTFRSEEKGIIHLPIHGLKELYLLNEITLNSKLLSFLSMAGITVHFFDYYGHFRGTFYPKDARVSGKVKLLQAKACLERRIPIAAAFIGAIAANIHEVLYHYYKHGNKEIKPYLDWLKKDVPGLLDKMEDIPRLLSVEGEIWRRFYDTFKTFLPEDFKMNKRVKRPPDNPLNALISFGNTILYTKTISQIYHTHLDQSISFLHEPSDRRFSLSLDLSEPFKPLLVYRTIFELVNNRRIQVNKHFEKDYNYCILNGTGRDVFITALEDRMKQVFDHGTLKRKVSYLSAIKYDAYKLKKHIVEGTPFVPFLEKEKR
>NZ_CP045298.1|WP_007429323.1|3727905_3728400_+|CRISPR-associated-protein-Cas4
MRITGTMVNYYVHCRRQCWLFANGMNFEDDSEDVRIGKVMHELQSEGKKNREVAIEGIKVDKLTSDYVTEIKKSDADVEATKWQTLYYMYVLKQKGMERKGKIQFSERNKQASKTIELELDEAAEQAMEQLLAELEQYLQQEQPDPAIREKKCTRCAYLAYCFL
>NZ_CP045298.1|WP_152382197.1|3725197_3727909_+|CRISPR-associated-helicase-Cas3'
MPIHVSIQHWLTEEGKGRLKAHTAIEEGLQQDEMLEEHSDLVMHHAEILMRDHGVEAAVHRALDRLGIDGEPLDESLRQMIMYYFRQAIYLHDLGKVNPAFQRIKMKNNEVKRNAELGDSNHSMLSAVLYLHIHLRQVQEWHDTTELYPNRKKHKRKVLAFLHHLLYSFAYTISRHHTYLGNMDEDMGGQINEFELKIRNQYNRIKENPDYIRYYRDQQDLLQNDNVFGCIRLEGNKRQNKIHRPFPFYVLVKLLYSTMVASDFRATYQYIEQQVPEMHYFGERLPVEPMLEAYRQTGIVRGIESYRQNPDASGLSEMNQLRAALFIETERRLLERLQEPVFYLEAPTGSGKTNMSINLALHLLNSGLGLNKLIYVFPFNSLIEQARQTLNGIFHKEQVNGYRVEVMNSITPMVTEEELEAEATLEGKDKEPDNTDFKRVLLERQLLQYPVTLTSHVNFFNYLFGTGREVNLAFAHLCNSVIVLDEIQSYRNELWKEMIHFLRSFADILNIKIIIMSATLPNLDLLLEQRDHEEAIQTYTLVQNRDRYFIHSLFRERVNLDFNLLKQGKMQPEQVLEHVESVIKRRKRDGQGNRVLIEFIKKKTARQFYNLVLEQDTDIDVYELTGDDSFSYRQELLQKLGKDEHGRFYMSDVIVVATQVIEAGVDIDMDVGFKDISLLDSEEQFLGRLNRSCLRDYCQAYFFNCDEASSVYKNDLRVAFDLKEEAYQKMLENKDFSGFYENVIREINKSREKPDKQHWSDFTKKVQELEFPDVQEHMNLIPDQSVTLFLNYTCPMKDAPPLNGQDVWDEFVRLSDKRLEMDYSERMIRLSLVRAQMNNFTFIYPVPHMYAKWGKVKPGIHTRCIGTLYFVEHGEQYMDMDERTNTKKFNRARYEEAEKRLLL
>NZ_CP045298.1|WP_152380917.1|3724270_3725071_+|type-I-B-CRISPR-associated-protein-Cas5
MQALRFELSGETAFFKKPDVNVYAYFTYSHIHKVALYGLLGAVLGLGGYTQQYERNMALGGKAKQDNPAMPYPEFYEVFRDASVSIVPHGDRGYFSKKIQIFNNTVGYASQEEGGVLNVREQWLERPRWTIYVADDGGVDREVFDRLADYVQHSKAEYIPYLGKNDHPATISKARLVELEPVDEPEYIDSLRAAHLSADVGGYVKDDQMQSYLQEYLPVGLNAANNGYILEPLVFSNQEIDTDELKAEDLQKMYRDADNGRTLYFI
>NZ_CP045298.1|WP_152380916.1|3723231_3724236_+|CRISPR-associated-protein
MAKKTNRVVGLIGIVSRMANWNADFSGQPKTTSTGQIFGSDKALKYSIKRLWAEEGQKVLYIRSYKVSSGKDKKVDKAKDADKGKEEKLQPRNLAERYEYLFGEEVSKNSREVLSKLFQCVDVMNFGATFAVKDQNIGLAGPVQIGQGFNKFDWSNLEVQDILSPFRNSNEKSEDNDATSIGKKRTVDESHYVYPFSVNPKHYDHYVELLAAGGFEGYTEEAYQAFKTGALTGATLQNTNSKSGAENAFALFVEFKAGSPAYLPNLDPYVKVDKDKDGEQTVYDLSALAPLLNDVNEEIETVELYVNPYASRVELDFPGLRTFNIFTRSELPQG
>NZ_CP045298.1|WP_152380915.1|3721226_3723248_+|hypothetical-protein
MLKDLTNSYLLAKKEFPNITFDRHRPKEGLYIRLRLDQSWNEQVSQFDSEYMIITKEEPDLTHNKLFEWFQQKDYVSSLISMNKAVDPGKQLHSNNPYTLYAKRDVFLAETQADGTTAMQAHVARFLDKTQATEVQKKWDELIGVKKTGSTSSTQQFFSQTDYAPALEYLVSEERRTSIAQIEQWYATNLSAFIDHIRTIPFKNYVKIFFTPESISLNSSNNNLFNESSSLYSWDEIYGYEYLLYTIPKIFNSNDYNQMVDGALTGLPGFNMSMNSKKPYLEHKTMRVGAPVRLSLEEALRVKEATEWLISQPKFRMNKFSYYTDFSKSISDAAEGYFFVYVEGKDNEIQDYENVPFSKQVYVNIRLKNALGLMTKNNDGEAFMKDYGYLENVEQLQKEISRRFFRGRMNGDFLQDEPKAREKDFTSGMVALFMQSKKGFHDWFFKGTTATIRSQFARVTLRLLEEQLLRVEPAGQEKSKLDLSGLADAMNVRLSLMAHLEGEEYTAMGNRLIAVSNKLKEKLDTLDKRKQKENAHGAGQTEQTANPEPVYVETDDEFYYLAGQLAFYLKSQSEAQQKKGDLLGPFFMAKRSGQLKRRIEEAYHLHRHKILLQYTKLNWALANVNAYQPDKEFQHEDAREMFLAGLFSDNWFWKKGENEKPSSEGENGHGEEN
>NZ_CP045298.1|WP_152380914.1|3720500_3721205_+|CRISPR-associated-protein-Cas6
MYFEIHVTTLIKQFSHHLEIPERIGAWIGRAGLNDETLKQTHYDKDYKHYTFGSPFPREKAGVYKQGRVYVITIRSSIEITLRRISAALQALQEDEYFQFIAASPVQSKKLVHITELTTVTPAIVTIEGKPWVPGLSVELLLQRIHANAEKKYNHLYPDQPVRLEQPFIEGIQVLNHKPIALAYKGRKLLGNKLRLLVREDEYSQKLASVVLGSGAAEKNSILGAGFCIAKGLE
>NZ_CP045298.1|WP_152380913.1|3718132_3718981_+|DNA-binding-protein
MKAFDFDEVTDLDSIVGMLKMAFSLEEWEQMIQIADQLHTQAHRVYEQQQLELTKGGQPRTLHIKRPLVYYLGFSQLTKGIAFQKQGKYESSRECVEKYAELGWVEGLNEEGLQEVEDYRTLAKANTYTLDLLQGKEEVLPNYVRFLHENSSEELLPGMITILESTIVHNYNINGILREFKTRLTELGTFYEEPENIRYYVTYLYLLAVYRFIEEKYTVAIEVTLNALESADKKCVALFESFRSYANKYQKKKYKFIQKNVLERELKNEKNLLYDGYRIRIV
>NZ_CP045298.1|WP_152380912.1|3715814_3716522_-|response-regulator
MNPHILLIEDDTAIAEMMLKALTKEGYKLTTASDGVEGLLAFACHTYDLVLVDLMMPKVDGMEVIRRIRTSSAVPILIMSAKDSDVDKALGLGFGADDYVAKPFSMLEMTARIQSAIRRSTTYARQQRQEEQPKAQILSYGNLHIDFDHFTVIRNKNEIQLTAKESDILKLFVTNPNRVFTKAQLYGFIWKEDYMGDENVINVHIRRLREKIEEDPSHPIHIKTLWGIGYKWENG
>NZ_CP045298.1|WP_167518721.1|3730412_3730601_+|helix-turn-helix-domain-containing-protein
MPTDNKKSHTTKPRKQRKVKEEVTLSKIRELMLQRPGIKQKELAEILGISQSRVSQLKNKLN
>NZ_CP045298.1|WP_152380921.1|3731053_3732133_-|alcohol-dehydrogenase-catalytic-domain-containing-protein
MKAAILKQFGMPLAIESLPDPILGTGEVIVDVAAAPVLSYMKEVISGERKYLMLLPQAPGAGAIGRVRAVGPDSTRLAVGDWVYCDPTVRSRDDALTPDITLQGLSARGEGGLHLQKHFRHGSYAQQILIPTENAIRVGSLDNEDAGKWCAFGTLAVPYGGLLKANLQAGETILVSGATGSFGSACIALALAMGAGCVVAPGRNEETLEDLSRRFGSRIRTVKLSGDEDDDRKRMQQAAPGPIDCVLDILPPFAPATAVRAAVMSVRPYGRAVLMGGVGMLGGAGLDLPYPWIMRNCITIHGQWLCPAEAPSRLVALIQSGLIALEQFDITAFDLDHANEAIEHAAANPGPFKLTVIKP
>NZ_CP045298.1|WP_152380922.1|3732258_3733077_-|helix-turn-helix-domain-containing-protein
MGDDSKRRKELGAFLKTCRLRLSPAEFGIQSSPHRRTNGLRREEVADLAGLSTIWYTWLEQGRDIRPSSQVLESLGKALRLNRHELLYLYTLAEHRPPYDLQADTQVEPSLQRMLDKLEPFPSIITGPRWDVLAWNQAACELVGDFNRMNTLERNSLWRMFVCPDYPDSLPEWPKVAKGLLAQFRSSYGRHIGDPWFEELVELLKKESDTFKDWWENHEVLSIPPGTKRIRHPVKGELEFDQQSMTLADHPDLKVTVYIPCIPLLDVQMSQV
>NZ_CP045298.1|WP_025718655.1|3734242_3734746_+|hypothetical-protein
MFVIRGTQKLLKEWAAEPLHVDIYPPLNSWHASLFLLNRRKNIVFMHDASRLSITLFGIKKSQYKHLPTLFVQALKELMISEGFDEQIVKAYTQEGEQMLATTTNSYSVMRTLDEIIFVMRELDMEHGCELEKNQWNNRIVFKTVQYQYPVDAFKEALEKHYKLESV
>NZ_CP045298.1|WP_152380923.1|3735370_3737002_+|formate--tetrahydrofolate-ligase
MKRIIEVAKEAGIEEEHLETYGKYKAKLNPSLWEQLKDRPNGKLVLVTAMNPTPAGEGKTLTTIGLSQALNALGHKTVAALREPSLGPCFGMKGGATGGGKAQIVPAEDINLHFTGDIHAISAAHNLLAAMIDNHLFHGNALRLKPERIVWKRAVDMNDRSLRSIVTGLGTGNGAVRESGFLITSASEVMAVLCLSENMNDLKVRLGRMVIGYNEAGETVTAGQLHAVEGMAVLLREALKPNLVQTLEGTPVIVHGGPFANIAHGCSSLIGTKLALKLGEVVVTEAGFGAELGAEKFFDIKCRQSGLQPDAAVLVITAKALKYNGGVSKNELDAENLEQLQLGLANMNRHVRNLQKFGVPVLVAINHFVTDHEAELELILAECRRLGVPAELSQVWAQGSRGGERLAQSLLNLLQEDKARFAPLYDAALDLPTKIGMIAKEIYGAAEVVYTAEAKRALSGMEQLGFGQLPVCIAKTPYSFSDQPSLLGAPEDFTIHVSRASLSAGAGFVVVETGNTMTMPGLPKSPAAEHMSLEADGSIQGLM
>NZ_CP045298.1|WP_152380924.1|3736937_3737267_-|hypothetical-protein
MGKSGFSSALCHPQGFQPVEPIQKVLDEGHGFIEIEPNELPAVRQGRVYFTDADRWNWSDAMTRQKLLTALPKLLGASLQDGRIFQKNTTLDPECFHQPPATYARRPGI
>NZ_CP045298.1|WP_025718661.1|3738299_3739574_+|outer-membrane-lipoprotein-sorting-protein
MRRISWMLAMVMCVTLLLAGCGKKSADDVVKDLSDVVSDLNSYHGTALMTLHTGDTPQEYKVDISYRKPSYYRIAMTNEKKDVTQIVLRNDEGVFVLTPSLNKSFRFKSDWPNNQGQVYLYETLVRSIIGDASRQLATDDKSYVFDVAANYNSHALVRQKIWLSKSNYAPTQVQVSDANAKVVVDLKFDQFAFDTKFDKDSFDMERNMASGKTNTKSEGAPSSGAVDSSSQLNPGGAIDGATGVKSSESGQEQGTAGNAAQQQSGKAKVDGAATDDTSKSDTAASTEQKQNPEASDAATGTSAGTDAAEAMMGEFGLIEPSYTPAGVQLKDTPELEENGTHAVMLRYSGTYNYTIVEARPKDRAVALTAGELVDIGGSFAVLTGSEQQTLTWMNDGIEFRITSADLPVSEMIQIAASIQDQSGK
>NZ_CP045298.1|WP_025718663.1|3739844_3741041_+|alanine-racemase
MQAQYRSTRAEINLDHLGANYEAFRKALPADKLLLVCVKANAYGHGAVEISKELERLGVDYLSVAFLDEALELRHAGIELPILVLGYTPPEAVQTAWEHDISLTVFSEEVLEGIRRLDRKGSGRKLKVHIKIDSGMGRLGLLPGETAIAFMQQAGQLEQVLLEGMYTHFARADEEDKSYTLLQYDRFRGVVEALREHGITIPIIHTGNSAATIDTPSLSPNLVRIGISIYGLYPSDEVNRQAVALLPVLSLKTAVVYTKTLPPGWGISYGTRYVTSSEERIGTLPIGYADGYSRMLSGKVDVLIRGRRVPVLGTICMDQCMVSLQSFAEDAEEIQTGEEVVLIGQQSGEAIAADELASKLGTIHYEVICMIAGRVPRVYTRGNAPVVRVNSLLPTRWN
>NZ_CP045298.1|WP_007429334.1|3741334_3741616_+|ribbon-helix-helix-protein,-CopG-family
MANLQNTKRIMISLPDHLLQEVDGIVAMENSNRSEFIRQAMKLYVGERKKRYIREAMQRGYMEMAKINLTMASEAFHAEEDANSTLGRTVSGV
>NZ_CP045298.1|WP_007429335.1|3741622_3741973_+|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin
MIVKRGDVFFADLSPVVGSEQGGVRPVLIIQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDAATHGFDRDSVVLLEQIRTIDKQRLTDKITHLDEETMRKVSDSLQISLGLIDF

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Crispr_ID: NZ_CP045298_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045298_7

4517735-4519712

TypeI

I-C

Consensus_repeat	Method
ATTTCAATCCACGCACTCATATAGAGTGCGAC	PILER-CR
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CRISPRCasFinder
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CRT

29 spacers

cas3,cas5,cas8c,cas7,cas4,cas1,cas2

The CRISPR arrays of NZ_CP045298_7

>merge|NZ_CP045298|7|4517735-4519712|PILER-CR,CRISPRCasFinder,CRT
GTCGCACTCTATATGAGTGCGTGGATTGAAATATCCGAGCTGCCAGAGGTACTGGGCTTGTGTGACCGTCGCACTCTATATGAGTGCGTGGATTGAAATCTTGAAACCCTGCTCGATTCGCTCGTCGTACACTGTCGCACTCTATATGAGTGCGTGGATTGAAATCTGTGAACAGTAATCCTGCTGTACAGATGTTTATTGGTCGCACTCTATATGAGTGCGTGGATTGAAATTCTCTCAATCTCGTCCTGATCTGCGTCACCGTCAGTGTCGCACTCTATATGAGTGCGTGGATTGAAATGACATTTCTGTTCGCAAGGAAAGTATGCCAAAGGGTCGTCGCACTCTATATGAGTGCGTGGATTGAAATAACTACGACCAGTTCATTGCCATGAAGAAATTTAGGTCGCACTCTATATGAGTGCGTGGATTGAAATAGCCTTGAAATGCCCGGTGCAAAGCTGGGAGAACGATGTCGCACTCTATATGAGTGCGTGGATTGAAATATATAGACCCTTGGAATCAGTTATCGAACGGAATGTCGCACTCTATATGAGTGCGTGGATTGAAATATATAGACCCTTGGAATCAGTTATCGAACGGAATGTCGCACTCTATATGAGTGCGTGGATTGAAATATCAATCGAGTAGGATTCAACCAGGTCACTGTAGTCGCACTCTATATGAGTGCGTGGATTGAAATACTAATGTTTAAAGCGAAGGCTTATAGTGAACTTCGTCGCACTCTATATGAGTGCGTGGATTGAAATCATACAACACAAAAATAATTGTACGGGACTGTATTGTCGCACTCTATATGAGTGCGTGGATTGAAATAGCTGCAGCAGGCACGCTCTCACAGAAGCATCAGGTACGTCGCACTCTATATGAGTGCGTGGATTGAAATCGTTTCCTTTGTTACGCGAGTATAGCGGTTGAGTTCGTCGCACTCTATATGAGTGCGTGGATTGAAATCAATGACTAACGGCAAAGAAGCATCTTGTTCAGGGGTCGCACTCTATATGAGTGCGTGGATTGAAATTGCGTCGCCGTCAATATCCTCTTCAGATTCAGCTGTCGCACTCTATATGAGTGCGTGGATTGAAATCTCAACCACCTTAAAAAACTCCCCGCGCTTATGGTCGCACTCTATATGAGTGCGTGGATTGAAATCCTCCTACTCTTGCTGTTTTTTGGGTATTCACTAATGTCGCACTCTATATGAGTGCGTGGATTGAAATATCTCGATCAAACCCCTTCTTCGTCGGGACGCCGTCGCACTCTATATGAGTGCGTGGATTGAAATAGCCAGTTGAATATAATCCAACTAACGATCATCTAGTCGCACTCTATATGAGTGCGTGGATTGAAATTGGAGCAATTACGCAAGGGAGGCGGAGGAAGCGGTCGCACTCTATATGAGTGCGTGGATTGAAATAATTTCCATTTGTATACGATGTAATCAAAATGAATCTGTCGCACTCTATATGAGTGCGTGGATTGAAATAGCTCGGGCCACTTGGAAACCTCATAGAGCGCTTGGCGTCGCACTCTATATGAGTGCGTGGATTGAAATTCACAATGAAGCAAGAAGAATCCTTTTTTGTTATGTCGCACTCTATATGAGTGCGTGGATTGAAATGTTGCGGGAGGATGCCGAAAACGCTGGTATTGACGTCGCACTCTATATGAGTGCGTGGATTGAAATTGGAAGAATTCCGGACTTTGATGACGGTGACGATGGTCGCACTCTATATGAGTGCGTGGATTGAAATCTGTTCCGCCTTTATCTGAAGCGAGCGTCGTACCAAAGTCGCACTCTATATGAGTGCGTGGATTGAAATTTCGAACTTGACCGCGTCGGTAAGGCGGTTAAGGTCGCACTCTATATGAGTGCGTGGATTGAAATTGCTATCGCAGTAATGTCTGTCAGTGTCGCTAGTCTCGTCGCACTCTATATGAGTGCGTGGGTTAAAAT

>NZ_CP045298|7|6|4517735-4519643|PILER-CR
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATCCGAGCTGCCAGAGGTACTGGGCTTGTGTGACC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CTTGAAACCCTGCTCGATTCGCTCGTCGTACACT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CTGTGAACAGTAATCCTGCTGTACAGATGTTTATTG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TCTCTCAATCTCGTCCTGATCTGCGTCACCGTCAGT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	GACATTTCTGTTCGCAAGGAAAGTATGCCAAAGGGTC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	AACTACGACCAGTTCATTGCCATGAAGAAATTTAG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	AGCCTTGAAATGCCCGGTGCAAAGCTGGGAGAACGAT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATATAGACCCTTGGAATCAGTTATCGAACGGAAT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATATAGACCCTTGGAATCAGTTATCGAACGGAAT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATCAATCGAGTAGGATTCAACCAGGTCACTGTA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ACTAATGTTTAAAGCGAAGGCTTATAGTGAACTTC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CATACAACACAAAAATAATTGTACGGGACTGTATT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	AGCTGCAGCAGGCACGCTCTCACAGAAGCATCAGGTAC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CGTTTCCTTTGTTACGCGAGTATAGCGGTTGAGTTC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CAATGACTAACGGCAAAGAAGCATCTTGTTCAGGG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TGCGTCGCCGTCAATATCCTCTTCAGATTCAGCT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CTCAACCACCTTAAAAAACTCCCCGCGCTTATG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CCTCCTACTCTTGCTGTTTTTTGGGTATTCACTAAT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATCTCGATCAAACCCCTTCTTCGTCGGGACGCC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	AGCCAGTTGAATATAATCCAACTAACGATCATCTA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TGGAGCAATTACGCAAGGGAGGCGGAGGAAGCG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	AATTTCCATTTGTATACGATGTAATCAAAATGAATCT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	AGCTCGGGCCACTTGGAAACCTCATAGAGCGCTTGGC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TCACAATGAAGCAAGAAGAATCCTTTTTTGTTAT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	GTTGCGGGAGGATGCCGAAAACGCTGGTATTGAC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TGGAAGAATTCCGGACTTTGATGACGGTGACGATG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CTGTTCCGCCTTTATCTGAAGCGAGCGTCGTACCAAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTCGAACTTGACCGCGTCGGTAAGGCGGTTAAG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT

>NZ_CP045298|7|7|4517735-4519712|CRISPRCasFinder
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATCCGAGCTGCCAGAGGTACTGGGCTTGTGTGACC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CTTGAAACCCTGCTCGATTCGCTCGTCGTACACT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CTGTGAACAGTAATCCTGCTGTACAGATGTTTATTG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TCTCTCAATCTCGTCCTGATCTGCGTCACCGTCAGT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	GACATTTCTGTTCGCAAGGAAAGTATGCCAAAGGGTC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	AACTACGACCAGTTCATTGCCATGAAGAAATTTAG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	AGCCTTGAAATGCCCGGTGCAAAGCTGGGAGAACGAT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATATAGACCCTTGGAATCAGTTATCGAACGGAAT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATATAGACCCTTGGAATCAGTTATCGAACGGAAT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATCAATCGAGTAGGATTCAACCAGGTCACTGTA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ACTAATGTTTAAAGCGAAGGCTTATAGTGAACTTC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CATACAACACAAAAATAATTGTACGGGACTGTATT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	AGCTGCAGCAGGCACGCTCTCACAGAAGCATCAGGTAC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CGTTTCCTTTGTTACGCGAGTATAGCGGTTGAGTTC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CAATGACTAACGGCAAAGAAGCATCTTGTTCAGGG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TGCGTCGCCGTCAATATCCTCTTCAGATTCAGCT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CTCAACCACCTTAAAAAACTCCCCGCGCTTATG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CCTCCTACTCTTGCTGTTTTTTGGGTATTCACTAAT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATCTCGATCAAACCCCTTCTTCGTCGGGACGCC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	AGCCAGTTGAATATAATCCAACTAACGATCATCTA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TGGAGCAATTACGCAAGGGAGGCGGAGGAAGCG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	AATTTCCATTTGTATACGATGTAATCAAAATGAATCT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	AGCTCGGGCCACTTGGAAACCTCATAGAGCGCTTGGC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TCACAATGAAGCAAGAAGAATCCTTTTTTGTTAT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	GTTGCGGGAGGATGCCGAAAACGCTGGTATTGAC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TGGAAGAATTCCGGACTTTGATGACGGTGACGATG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CTGTTCCGCCTTTATCTGAAGCGAGCGTCGTACCAAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTCGAACTTGACCGCGTCGGTAAGGCGGTTAAG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TGCTATCGCAGTAATGTCTGTCAGTGTCGCTAGTCTC
GTCGCACTCTATATGAGTGCGTGGGTTAAAAT

>NZ_CP045298|7|6|4517735-4519712|CRT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATCCGAGCTGCCAGAGGTACTGGGCTTGTGTGACC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CTTGAAACCCTGCTCGATTCGCTCGTCGTACACT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CTGTGAACAGTAATCCTGCTGTACAGATGTTTATTG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TCTCTCAATCTCGTCCTGATCTGCGTCACCGTCAGT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	GACATTTCTGTTCGCAAGGAAAGTATGCCAAAGGGTC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	AACTACGACCAGTTCATTGCCATGAAGAAATTTAG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	AGCCTTGAAATGCCCGGTGCAAAGCTGGGAGAACGAT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATATAGACCCTTGGAATCAGTTATCGAACGGAAT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATATAGACCCTTGGAATCAGTTATCGAACGGAAT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATCAATCGAGTAGGATTCAACCAGGTCACTGTA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ACTAATGTTTAAAGCGAAGGCTTATAGTGAACTTC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CATACAACACAAAAATAATTGTACGGGACTGTATT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	AGCTGCAGCAGGCACGCTCTCACAGAAGCATCAGGTAC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CGTTTCCTTTGTTACGCGAGTATAGCGGTTGAGTTC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CAATGACTAACGGCAAAGAAGCATCTTGTTCAGGG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TGCGTCGCCGTCAATATCCTCTTCAGATTCAGCT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CTCAACCACCTTAAAAAACTCCCCGCGCTTATG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CCTCCTACTCTTGCTGTTTTTTGGGTATTCACTAAT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATCTCGATCAAACCCCTTCTTCGTCGGGACGCC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	AGCCAGTTGAATATAATCCAACTAACGATCATCTA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TGGAGCAATTACGCAAGGGAGGCGGAGGAAGCG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	AATTTCCATTTGTATACGATGTAATCAAAATGAATCT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	AGCTCGGGCCACTTGGAAACCTCATAGAGCGCTTGGC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TCACAATGAAGCAAGAAGAATCCTTTTTTGTTAT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	GTTGCGGGAGGATGCCGAAAACGCTGGTATTGAC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TGGAAGAATTCCGGACTTTGATGACGGTGACGATG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CTGTTCCGCCTTTATCTGAAGCGAGCGTCGTACCAAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTCGAACTTGACCGCGTCGGTAAGGCGGTTAAG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TGCTATCGCAGTAATGTCTGTCAGTGTCGCTAGTCTC
GTCGCACTCTATATGAGTGCGTGGGTTAAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045298.1\|WP_152381400.1\|4523344_4525309_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	pfam09709_cas8c_CAS-I-C	gnl\|CDD\|187887
NZ_CP045298.1\|WP_152381403.1\|4531390_4532875_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|224089
NZ_CP045298.1\|WP_152381399.1\|4522628_4523348_+\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|273847
NZ_CP045298.1\|WP_152381402.1\|4527934_4528225_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP045298.1\|WP_025716873.1\|4505418_4505658_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045298.1\|WP_007430133.1\|4512083_4512359_+\|WXG100-family-type-VII-secretion-target	unknown	unknown	gnl\|CDD\|274862
NZ_CP045298.1\|WP_152378784.1\|4529289_4530407_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP045298.1\|WP_152381394.1\|4510451_4511294_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045298.1\|WP_152381393.1\|4506439_4510435_+\|type-VII-secretion-protein-EssC	unknown	unknown	gnl\|CDD\|274860
NZ_CP045298.1\|WP_152381401.1\|4526236_4526896_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|273040
NZ_CP045298.1\|WP_025716878.1\|4514752_4515505_+\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|238119
NZ_CP045298.1\|WP_025716886.1\|4526892_4527924_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NZ_CP045298.1\|WP_010346287.1\|4506051_4506372_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045298.1\|WP_152381397.1\|4516619_4517429_+\|3-oxoacyl-ACP-reductase-FabG	unknown	unknown	gnl\|CDD\|235546
NZ_CP045298.1\|WP_152381398.1\|4520026_4522516_+\|CRISPR-associated-helicase-Cas3'	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP045298.1\|WP_152382222.1\|4532984_4533914_+\|D-alanine--D-alanine-ligase	unknown	unknown	gnl\|CDD\|234948
NZ_CP045298.1\|WP_152381396.1\|4515517_4516354_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045298.1\|WP_025716884.1\|4525374_4526250_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	gnl\|CDD\|226175
NZ_CP045298.1\|WP_152381395.1\|4512656_4514681_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236545
NZ_CP045298.1\|WP_025716876.1\|4511299_4511836_+\|WXG100-family-type-VII-secretion-target	unknown	unknown	gnl\|CDD\|274862

Protein	Function_ID	Function_description	E-value
NZ_CP045298.1\|WP_152381400.1\|4523344_4525309_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|187887	cd09757, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Zn-finger domain containing protein, distant homologs of Cas8 proteins; signature gene for I-C subtype; also known as Csd1 family.	6.21097e-172
NZ_CP045298.1\|WP_152381403.1\|4531390_4532875_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	9.23074e-128
NZ_CP045298.1\|WP_152381399.1\|4522628_4523348_+\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|273847	TIGR01876, cas_Cas5d, CRISPR-associated protein Cas5, subtype I-C/DVULG. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum. This family belongs to a set of several Cas protein families, one each for a number of different CRISPR/Cas subtypes, that share a region of N-terminal sequence similarity modeled by TIGR02593. This family represents the Dvulg subtype of CRISPR/Cas locus.	1.76269e-95
NZ_CP045298.1\|WP_152381402.1\|4527934_4528225_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	9.97673e-31
NZ_CP045298.1\|WP_007430133.1\|4512083_4512359_+\|WXG100-family-type-VII-secretion-target	gnl\|CDD\|274862	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target. Members of this protein family include secretion targets for the two main variants of type VII secretion systems (T7SS), one found in the Actinobacteria, one found in the Firmicutes. This model was derived through iteration from pfam06013. The best characterized member of this family is ESAT-6 from Mycobacterium tuberculosis. Members of this family usually are ~100 amino acids in length but occasionally have a long C-terminal extension.	5.92216e-14
NZ_CP045298.1\|WP_152378784.1\|4529289_4530407_+\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	2.29228e-43
NZ_CP045298.1\|WP_152381393.1\|4506439_4510435_+\|type-VII-secretion-protein-EssC	gnl\|CDD\|274860	TIGR03928, T7_EssCb_Firm, type VII secretion protein EssC, C-terminal domain. This model describes the C-terminal domain, or longer subunit, of the Firmicutes type VII secretion protein EssC. This protein (homologous to EccC in Actinobacteria) and the WXG100 target proteins are the only homologous parts of type VII secretion between Firmicutes and Actinobacteria. [Protein fate, Protein and peptide secretion and trafficking].	0
NZ_CP045298.1\|WP_152381401.1\|4526236_4526896_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	7.96569e-27
NZ_CP045298.1\|WP_025716878.1\|4514752_4515505_+\|VWA-domain-containing-protein	gnl\|CDD\|238119	cd00198, vWFA, Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains.	7.72046e-08
NZ_CP045298.1\|WP_025716886.1\|4526892_4527924_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NZ_CP045298.1\|WP_152381397.1\|4516619_4517429_+\|3-oxoacyl-ACP-reductase-FabG	gnl\|CDD\|235546	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG.	2.74028e-91
NZ_CP045298.1\|WP_152381398.1\|4520026_4522516_+\|CRISPR-associated-helicase-Cas3'	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	7.82399e-72
NZ_CP045298.1\|WP_152382222.1\|4532984_4533914_+\|D-alanine--D-alanine-ligase	gnl\|CDD\|234948	PRK01372, ddl, D-alanine--D-alanine ligase; Reviewed.	2.43623e-144
NZ_CP045298.1\|WP_025716884.1\|4525374_4526250_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|226175	COG3649, COG3649, CRISPR system related protein [Defense mechanisms].	9.72403e-128
NZ_CP045298.1\|WP_152381395.1\|4512656_4514681_+\|hypothetical-protein	gnl\|CDD\|236545	PRK09510, tolA, cell envelope integrity inner membrane protein TolA; Provisional.	1.11e-10
NZ_CP045298.1\|WP_025716876.1\|4511299_4511836_+\|WXG100-family-type-VII-secretion-target	gnl\|CDD\|274862	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target. Members of this protein family include secretion targets for the two main variants of type VII secretion systems (T7SS), one found in the Actinobacteria, one found in the Firmicutes. This model was derived through iteration from pfam06013. The best characterized member of this family is ESAT-6 from Mycobacterium tuberculosis. Members of this family usually are ~100 amino acids in length but occasionally have a long C-terminal extension.	4.68428e-06

>NZ_CP045298.1|WP_152381397.1|4516619_4517429_+|3-oxoacyl-ACP-reductase-FabG
MSYTSAGNARFEGKTALITGAGSGIGKATAIQMAREGANVALFDVSNERILETEKEINAIREGSARAFDVDIADPVRVEKAVLEAVELFGGLHIVFANAGINGVVGPIEDLSIEDWRQTLSTNLDGTFLTVKYTVPHLKKNGGGSIIITSSINGNQRFTSFGMSAYSTSKAGQTGFAKMAALELAKFRIRVNVIYPGAISTNIDETTEKAERLKQITIPVKFPEGGQPLANGPGQPEQVADLVTFLASDHSRHITGAQIVIDGAESLLF
>NZ_CP045298.1|WP_152381396.1|4515517_4516354_+|hypothetical-protein
MNPLLSLLPASKRKGMNARLAQHFDYISSQTGDQPLSSHHSRFKCRYGYGRSAESASMGESGQDFAAVRIHKTVCCFVLCDGVGLSYRGDFAARYLGSSLLDWLEEGRDLSAEQLRMYLERLADTATVELDRQPLNHESGLMRSVLEDKRRQGSQSMYICGKIELPKRGARGRLRLAWQGDSRLRLWNGAEEISDLFAHTFSTAERWSTSRGPIGGKPHWYERSIPADMPMRLQVYSDGLSDLDPICEPVPDEQIQVLLDASHTGGLDDDAAFIELQW
>NZ_CP045298.1|WP_025716878.1|4514752_4515505_+|VWA-domain-containing-protein
MNYTIQASQRTPALIIYLIDISASMNMLMEGRRRIDVVYEAISLAIRQMVFRSTKGNRLTARYRIAILAYSDDVYDLLNGVKGIDEIAAIGSLPDLTPKRFSDSAKAFLQAERILQAELPGMQDCPAPLVCHMTDGVSTGDDPEPIAKRIMSMSVPDGNVLVENIFLSDRLLETPIQDPRRWKGLTHTTPLQDEHAVKLRNMSSVLPESYREMLFEADYQLGEGAIMMLPGTCAELVSIGFQMSAATPVR
>NZ_CP045298.1|WP_152381395.1|4512656_4514681_+|hypothetical-protein
MSFQPNPGDELIINGTAYVVGRHPVAPGLAYAQAGRQGIVYQLNAKSGAPHEAKALKVFFPKFRIPAMVYQSEHMEAYGDIPGLQVCKRDVLTPERNGSLIAEQPDLLYAVLMPWVHGTTWFDCLTDQRQLEASDSLALARALAGIGSAMEQKGLAHCDLSAPNVMLPFFSEVELPEGTSAVELVDVEQMYSTKMDRPDALLAGSPGYAAHRTVHSGLWSAYADRFAGAIIIGEMLGWSDRVIVDKAWGESYFDQHEMQTPCERYFILRKSLESRWGSKVVELFSRAWDSQDLSSCPTFGEWLVVLNGITEQEIPVEVEATELEATETAQAAAGSSSFQTASSLVAPLEAEQAALLNQAAEEQGQRGVTDKLFRQARDLEQQNKPAAALEVYRSLYHFVEDGSPLHVEVSAAITGLEEQLNPMTPEQPEKSAAWYRSKTFIASTAAAVVLLAAGIPTVKILADQSNQRQIEAAKQEEAVKAAQAKLAAEQEAAQKVLAEKQRQEAEEQAKQQALTQKQQEEQKKQQALIDQQIKYEAYLAQKEKDKQAAAKLAKQKAYDQQAKYEKYLAWKKDQEARAAQEEAARKAAAEAAHKQEASMHARNKENVLQLISLYNKAYASQEGGSTAKAKSFANRFRALYDSNPSYYRKVGEVGYRASSIYNFLSDTNFRLPKI
>NZ_CP045298.1|WP_007430133.1|4512083_4512359_+|WXG100-family-type-VII-secretion-target
MAGRILITPEQVDQVANQFKQSGEQSQQIVSSLTQSISGMEGQWEGMTKQRFFQEFQEASKQMQAFVTTLNSISQELTAIANKFRTVDQAK
>NZ_CP045298.1|WP_025716876.1|4511299_4511836_+|WXG100-family-type-VII-secretion-target
MRIRVEPDVLRGLSGQLQHAAEQIQQLTAGLEQALQSLDWDVSARETVLDHWMQAKRMSEQIHAYLHTSGAQLNRKAEEFQSVDHNYQTILSFASQSLGRPVTMLDWSNQQSPSILPGQTSEGSGLISNPQSVVHAITGIPSSDVGTLNQDILEQASSGSPQDWYFTDPSVVRDQPVA
>NZ_CP045298.1|WP_152381394.1|4510451_4511294_+|hypothetical-protein
MLTFQASKQKLITLKSKELFFLAGVLGSDRLLGVEDPFKGYLAEELAEEWEQVKAALLEKGYLKRVDKGKELAMPPTVFSRVAIAGLSNRACHIRYTRGGKRFEGYLHCTNERVVELVKSADEPDEYRLYDLGNVEKACESLIDEMGWVDRLVPESPALMFSKQAFNEIYKQSEGENVSLISSKLTEASGDAEGAAKLAQSLSSRVAEGELQLLVWNGREWESQRAAFVLCPAMSWIFRMSSNGNGDWLIAAMTSRDQFVDLLLNWLRQSTVTEEATEEG
>NZ_CP045298.1|WP_152381393.1|4506439_4510435_+|type-VII-secretion-protein-EssC
MNVLYQRSPRLRPALREEKLEILRPPAEPSKPSFSIISILIPLMMTLVTVGFYVYMSRTGKMGNSNYLMFQMVTVVMMLTSYTIPFFVYLNNKKEYKRKLEERDRMYREQLQKHREELELKREEQIRTLYEIHGDPQICAQIVKNRNSSLWERSPEDEDFLQVRIGTGQVPFHIKLQIPRPDGYDRDPLLGAADELEEEFRLVDAASIALPLFQSKVVGLVGEREHTLAALRVILAQVAVRHSPDEVKIASFYDEREESEWAWMRWLPHVWDDDRTQRMMSDRSSSAHQLADFLFARLNRRKNNRSERHGKGMEVPCYVIVLSDSQLIEEEPLLPLLLEDGRAIDACTIVLASRKEALPMQCQLIVEASKEQGVYARKSESAEVEQQSFKPDRLSKEEADALARYMAPIRLKRSSASDIPSVLPLFDMMSVADVEELDVTERWRRNRHPDTLPVPMGVRAGGKKIMINLHDKIERQGHGPHGLIAGTTGSGKSEVIQSIVASLAAEFHPHDLAFMLIDYKGGGMSNTFVNLPHVVGTITNLDNNLIERAKISLKAELVRRQKILNDAGNLQHIDEYYRLLRQRHEQPLPHLVIIIDEFAQLKRDQPEFMDELISIAAIGRTLGVHLILATQKPAGVVDDKIWSNSRFRICLRVQSEGDSRDMLKIPNAAWITKPGRGYFQVGSDEVFEEMQFAWSGAPYIGNSDISSALPVHEVRLNGKREALLTGGERASSGLKGEEAPKQLQIFIDYIANEAAKAGIERLQGPWLPPLPELLDLTHLSPCTQMDSASAPEELKALIGLVDDLPNQRQESIYAALDHGHWAVYGMPGMGKTTFLQTLLMSTAQRFDANRWNGYIIDMGRTMRDFGDLPQIGAVMMAEEDDRIKRLFRYLFKLVALRKEMISEAGVKTISSYRRSAVEDVPQIVVAIDGYLNFRNAYPDENELLESLLREGGSLGITFIITANRITDVFEKFRSNIPNAVSFELSDPSDYYYAVGRPAKTPGSLIPGRALVKGHIPPLEFQTALPSPGGDETERSAQLRRNIASIVQEWKGAHAPAILPLPERIPLAELLQQWDRTSGPSGALPYEVPVGLQSDDLEPFLLNLKEGPNFIVGSPMEGGKTSFLMSWILSLAYYTSPGQLEVFTLDTRYGGGGLSRLRHLPHVKAAAESEEEIGPLVQQVHDIVQQRSKDGNDPELLLVIDDADMLSKQLNDFIIKDQLSAIVRLGRDRNVHVVLSGVPSDFPTFGVDWFNDVKASQSGVLFGTLDSNDLSFFRIPYSEANAAAGGLKVLPPGQGYYVRRKFTRIKAAIPFSEQVSCEDWITKIRDRWHVVV
>NZ_CP045298.1|WP_010346287.1|4506051_4506372_+|hypothetical-protein
MILTVLSGRQETEWFDIEVADEYSVEHLKLMLGVRIFGEPPAEGMQYIMEAKFPEGLWFRVEDDQLLTGAGLREGCTVRIQRAFSTTQDEAPVYGRRSLFQNEKNG
>NZ_CP045298.1|WP_025716873.1|4505418_4505658_-|hypothetical-protein
MRTLITFQNKRIPVYFNQDNKQPMQKTLKLLSNTLENKISSGKRALQKCLNSLISIEIIGCEAILHSVSENDSLALSLY
>NZ_CP045298.1|WP_152381398.1|4520026_4522516_+|CRISPR-associated-helicase-Cas3'
MEYIAHIRESDQVIQTVAEHLLETRQLAEAFGDKIGIRHITGLAGMLHDLGKYTEEFQHYIRLAVQNPDNPPKRGSVDHSTAGGKLLYKLFHIQPQGAFDQQDFMNKALLSEVVGNAIISHHAYLQDFLDPTLESKFLDRVRDRELEGFDHAVSLFYEQVMEKSAFFRYVNQAGTELAHYMKREDKTDIELKMMFLSKFVFSALIDADRTNTRCFEENNAKNEKNSNAPMNRQQLFQTYYERLMERINDLQSGENADTTINLLRKQMSEQCEQFADKPSGILTLSIPTGGGKTLASLRYALKHAVTFEKKHIIYVVPFTTIIEQNAQEVREIIRDDANLLEHHSNVVMNEVEDIDGEDHELEDVVVNTHQKLKLAKDNWDSPIIFTTMVQFLNVFYADGSRNIRRLHNLSESVIIFDEVQKVPTHCISLFNQALNFLKTYASSSIVLCTATQPELDFVHNKLDIEPDTEMVHDLDHVIEKFKRVEIVDKATDDTLDTEKLADFVEQILADESSILVILNTKAVVKNLYHRLTEGNGTIPVYHLSTSMCPAHRNRILEEVKQHLEHKKPVVCISTQLIEAGVDISFDCVIRSLAGMDSIAQAAGRCNRHGRDGTKQVYVIDHEEEDLKRLKEIKIGKEITRKMFIDLKRDETCYGGNVLSAQAMEIYFKKYYTELETDLNYFIPQLRRNMTELLSANRRENTYYRSYYDEKGTILPLFLANCYKTAAEHFQVIEDHTTAIIVPYGDGDKEGKEIIADLNGQQSIEDLTSLLRRAQQFTINIFHYEKKQLDQNKALVSFLDGKILALTEGAYHDSYGLNLENDSPHGGFFI
>NZ_CP045298.1|WP_152381399.1|4522628_4523348_+|type-I-C-CRISPR-associated-protein-Cas5
MRNSIEFRVYGDYALFTDPLTKLGGEKLTYNVPTYQALKGIVESIYWKPTITMVVDKVRVLNAIRMESKGIRPIEYGGGNTLANYTYLKDPCYEVQAHFIFNLHRPEMEYDRNENKHHNILKRSLLAGGRRDIFLGTRECQAYVEPCVFGEAPGFYDSYGEIHLGNMVHGINYPDETGRNQLEVRLWNPVMKDGVIEFIPPEKCPQVRVIAEMQPKRFDENNVQSADELLAEWEGWGMK
>NZ_CP045298.1|WP_152381400.1|4523344_4525309_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MSWLLNLYETYKSNLGRVGVPEKKRDGREYTLLPISHTTQNAQIEVEITEQGDFHSARVLDKDEFSTLIPCTEKSASRAGSVVAPYPLHDKLSYVAGDFVAYGGKVKKEEPFATYIQQLEGWANSEYATPKLKSIYRYLSKRQLIKDLSDHSILYLDENQQLITKWDKKYERSPGEKPRIFTAVPGELESAFIRFNVYSPDKALTKVWLDTELYDSFISYYSQLLGEEDICYVTGKQLPSTDKHANKIRNSGDKAKLISANDTSGFTFRGRFADSHEAASISYEVSQKAHNALKWLIHRQGKIMDNRVFLVWGNDDPDVLSFTNNDNIFAMDFGPESSRPTAIKSHTNEELAFDLAKALSGYRNKLAVKSTSKANVNILVLDSATTGRMAVLYYRNLDKKLYFDKLIDWHSKCAWLHRYQKDEQGELLQFFGAPATKDIAFATYGPKANDKLVKGLMERMLPCIVDGRPVPQDIVRSATHRASNPVAMDKWEWEKTLSITCALINTQEGYNVSLDEEIRDRSYLFGRLLAIADVLERNALERSGQDRDKKRSTNAIRYMSVFSQHPERTWRTIQNALQPHQAKFGKQLNYYSIMIDEVASKIPFDEFNNEPLTGKYLLGFYSQRYEIYHNTDKKRHEGNNAGDENNQDDNIPGM
>NZ_CP045298.1|WP_025716884.1|4525374_4526250_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MSILDHKIDFAVVLSVAKANPNGDPLNGNRPRQNYDGYGEISDVALKRKIRNRLQDMGESIFVQSNDRKLDSFHSLRERAEANPELGKIFKSKEGSSEEFAKMACQEWMDVRSFGQVFAFKAAGKGAGVSVGIRGPVSIHTATSVLPIDITSMQITKSVNSEPGSEKGSDTMGMKHRVDFGVYVFKGSINTQLAEKTGFTNEDAGKIREALISLFENDVSSARPDGSMEVHKVYWWEHNSKLGKYSSAKVHRSLEVKPKENVNAADKSFDTHYECILTPLEGLEVQEYAGL
>NZ_CP045298.1|WP_152381401.1|4526236_4526896_+|CRISPR-associated-protein-Cas4
MQGYNEEDYLLLSGIQHFNFCRRQWALIHIEQQWEENVRTIEGNHLHRKADQPMIREKRGDKLVVRALPVHSRELGITGICDVVEFARDPLGVPLAGEEGTYLPFPVEYKRGKPKRNDSDHAQLVAQVMCLEEMLVCEISKGYFYYDEIKHRVEVIITAADRERVRTSLQEMRHYFEQNHTPKAKAGPHCLSCSLHNICVPEILNKKSVSSFIESRLAE
>NZ_CP045298.1|WP_025716886.1|4526892_4527924_+|type-I-C-CRISPR-associated-endonuclease-Cas1
MKKLLNTLFVTMPDTYLSLDGENIVIKQEESILARYPLHNLEAVCTFGYSGVSPGLMGACATRNIDLTFMTRSGRFLARVTGESRGNVVLRKEQYRISDDDRRSALVARNMITGKIYNHKWILERATRDHQLRIDTDRLKKVSTSLTEIMKQVREVEELDILRGLEGTAAVQYNSVFDELILQQKDNFYFHGRHKRPPLDNVNALLSFAYTLLSNDMKSALEAVGLDAYVGFLHRDRPGRASLALDVMEELRGVYADRFVLSLINKKLIHGKGFYKKENGAVMMDDDTRKIVLKAWQERKQDKIIHPYLNEKMSWGLVPYSQALLLARHIRGDLDEYPPFLWK
>NZ_CP045298.1|WP_152381402.1|4527934_4528225_+|CRISPR-associated-endonuclease-Cas2
MLILITYDVSTVDREGRKRLAKVAKKCVDHGQRVQNSVFECILDSAQFRRLKYELEELIDKKEDSLRFYNLGDNYKKKVEHIGTKEAYDMESLLIL
>NZ_CP045298.1|WP_152378784.1|4529289_4530407_+|IS3-family-transposase
MPRQRRTFTADFKKQMVQLYDNGKPRAAIAREYELSPSALDRWIKQAQTSGSFAEKDNRTAEENELLALRKENERLKIENDIFKASRADHGTKVKIIKQNSDKYSVSALCEVLQIARSTFYYEAKEKDNEDEVTTAIVEIFHTNRKAYGTRKLKVKLQEQGYTVSRRRIGRIMKEQGLVSTYTIAQYKPHKTACNEATTANVLKREFDQTEAKRFVVSDLTYVKVQHKWHYICVLIDLFNREIIGHSAGPNKDAALISRAFATVEGDLSDIQWFHTDRGSEFRNQTMDELLETFDIGRSLSMKGCPYDNAVAEATYKVMKTEFVNQMNFQSLHHLKLELYDYVNWFNKHRIHGTLRYMTPVQYKAAALKKVV
>NZ_CP045298.1|WP_152381403.1|4531390_4532875_+|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MFQDFKLVSDRPVSIQVKEYVNRLIIKGVLQADQKLPSTREMSVLLKVSRNTVIAAYEGLEDDGFTYAIPGKGSYVAAMMGQSDVDNGGSDSSATWEIDWKMRMNEYAVSAVDLDMMKQGIRAQKGTISFTSIAPDEQLFDLGDVRRAFMDRMAIEGQVLLNYGYAKGYKPLIDYLMHYMENKGVDISGKDMLITGGFTEGFDIVLSALRPSGRRGAAICENPTHYTAIKNLKLQGFEITGIPMERDGIDVERLEAVLQTNSFDLAYLTPSYHNPTGIVMSPAKRSAVMKLMTRYQIPIIEDGFNEELRYSGAHVAPLIASAGHGNGVIYIGSFSKVLFPGLRVGWVLGDRALIDTLESIKRARTIHTSTIDQSILYQYMLNGNFDKHVKKARTEYKRKYELTKACCEAHLPETQVSGDGGLHLFLTFPAGVNTRQLLEDCTEQGVIFTPGDRFFIQEGEGTNTLRLGFSRVTDENIERGIQIIGKQARSFPKA
>NZ_CP045298.1|WP_152382222.1|4532984_4533914_+|D-alanine--D-alanine-ligase
MKIGVIMGGISSEREISLQTGQEMINHLDRSRYEVIPIVIEQRADLIVQVQQAGIDIALLALHGQYGEDGTVQGALETLGIPYTGSGVLASSLCMNKQLSKTLLKATGVHTPAGLCWQGMDDYDPQVVERLGYPVIVKPNTGGSSIGIQLVQNEKDLLPAIQEACSLDQAILIEPYYKGTEITCSIVDGEVLPIISISSARSKWFDYKAKYEVGGAKEEVIELPPVIEQRVREAALASYRLLQCKVYARVDMILCQDRPYVLEVNTLPGMTANSLLPKSAAAAGITFTQLLDHIIAISLHERKQEWGMA

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Crispr_ID: NZ_CP045298_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045298_8

4528407-4529175

TypeI

I-C

Consensus_repeat	Method
ATTTCAATCCACGCACTCATATAGAGTGCGAC	PILER-CR
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CRISPRCasFinder
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CRT

11 spacers

cas2,cas1,cas4,cas7,cas8c,cas5,cas3

The CRISPR arrays of NZ_CP045298_8

>merge|NZ_CP045298|8|4528407-4529175|PILER-CR,CRISPRCasFinder,CRT
GTCGCACTCTATATGAGTGCGTGGATTGAAATCATGGCGCTCTGGTCATTGGTCGTTGTCATCGCTGCCGTCGCACTCTATATGAGTGCGTGGATTGAAATTTTGTCGAACTCGGAAGTTGTTTCTTCCAATTGTGTCGCACTCTATATGAGTGCGTGGATTGAAATTGACAAAAACGCCGGAGTCGCCTCCCGGACGCCGTCGCACTCTATATGAGTGCGTGGATTGAAATTACTTCCTCATAACGTATAGCCGCAAAACAACGTAGTCGCACTCTATATGAGTGCGTGGATTGAAATACCGCATACAGTGCATATCTTATGCTGCTGCATAGTCGCACTCTATATGAGTGCGTGGATTGAAATTCACCTCCCTCCGTGATATTTCTGTAGTCTGCGCTCGTCGCACTCTATATGAGTGCGTGGATTGAAATCAAAGAATACGGGACAACTCACTTTTATCCCGATCATGTCGCACTCTATATGAGTGCGTGGATTGAAATCTCCTCAATGTATGTAACCCCCTATCGCTCAGGTAGGGTCGCACTCTATATGAGTGCGTGGATTGAAATAAGTGCGATGCGCTCGTTGAACCACGTCGTTTTAAGTCGCACTCTATATGAGTGCGTGGATTGAAATCTCGCATGACCGCCGACTGTCGCTCCCGGCGAGGTCGCACTCTATATGAGTGCGTGGATTGAAATCTGTCTATCACTTCGAAATTATTAATAGTCGTTGTCGCACTCTATATGAGTGCGTGGATTGAAATC

>NZ_CP045298|8|7|4528407-4529174|PILER-CR
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CATGGCGCTCTGGTCATTGGTCGTTGTCATCGCTGCC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTTGTCGAACTCGGAAGTTGTTTCTTCCAATTGT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TGACAAAAACGCCGGAGTCGCCTCCCGGACGCC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TACTTCCTCATAACGTATAGCCGCAAAACAACGTA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ACCGCATACAGTGCATATCTTATGCTGCTGCATA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TCACCTCCCTCCGTGATATTTCTGTAGTCTGCGCTC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CAAAGAATACGGGACAACTCACTTTTATCCCGATCAT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CTCCTCAATGTATGTAACCCCCTATCGCTCAGGTAGG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	AAGTGCGATGCGCTCGTTGAACCACGTCGTTTTAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CTCGCATGACCGCCGACTGTCGCTCCCGGCGAG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CTGTCTATCACTTCGAAATTATTAATAGTCGTT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT

>NZ_CP045298|8|8|4528407-4529175|CRISPRCasFinder
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CATGGCGCTCTGGTCATTGGTCGTTGTCATCGCTGCC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTTGTCGAACTCGGAAGTTGTTTCTTCCAATTGT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TGACAAAAACGCCGGAGTCGCCTCCCGGACGCC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TACTTCCTCATAACGTATAGCCGCAAAACAACGTA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ACCGCATACAGTGCATATCTTATGCTGCTGCATA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TCACCTCCCTCCGTGATATTTCTGTAGTCTGCGCTC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CAAAGAATACGGGACAACTCACTTTTATCCCGATCAT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CTCCTCAATGTATGTAACCCCCTATCGCTCAGGTAGG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	AAGTGCGATGCGCTCGTTGAACCACGTCGTTTTAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CTCGCATGACCGCCGACTGTCGCTCCCGGCGAG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CTGTCTATCACTTCGAAATTATTAATAGTCGTT
GTCGCACTCTATATGAGTGCGTGGATTGAAATC

>NZ_CP045298|8|7|4528407-4529174|CRT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CATGGCGCTCTGGTCATTGGTCGTTGTCATCGCTGCC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTTGTCGAACTCGGAAGTTGTTTCTTCCAATTGT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TGACAAAAACGCCGGAGTCGCCTCCCGGACGCC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TACTTCCTCATAACGTATAGCCGCAAAACAACGTA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ACCGCATACAGTGCATATCTTATGCTGCTGCATA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TCACCTCCCTCCGTGATATTTCTGTAGTCTGCGCTC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CAAAGAATACGGGACAACTCACTTTTATCCCGATCAT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CTCCTCAATGTATGTAACCCCCTATCGCTCAGGTAGG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	AAGTGCGATGCGCTCGTTGAACCACGTCGTTTTAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CTCGCATGACCGCCGACTGTCGCTCCCGGCGAG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CTGTCTATCACTTCGAAATTATTAATAGTCGTT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045298.1\|WP_152381400.1\|4523344_4525309_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	pfam09709_cas8c_CAS-I-C	gnl\|CDD\|187887
NZ_CP045298.1\|WP_152381403.1\|4531390_4532875_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|224089
NZ_CP045298.1\|WP_152381399.1\|4522628_4523348_+\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|273847
NZ_CP045298.1\|WP_152382222.1\|4532984_4533914_+\|D-alanine--D-alanine-ligase	unknown	unknown	gnl\|CDD\|234948
NZ_CP045298.1\|WP_025716878.1\|4514752_4515505_+\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|238119
NZ_CP045298.1\|WP_152381397.1\|4516619_4517429_+\|3-oxoacyl-ACP-reductase-FabG	unknown	unknown	gnl\|CDD\|235546
NZ_CP045298.1\|WP_152381404.1\|4533915_4535106_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|181082
NZ_CP045298.1\|WP_152381401.1\|4526236_4526896_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|273040
NZ_CP045298.1\|WP_152381402.1\|4527934_4528225_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP045298.1\|WP_152381409.1\|4542464_4543460_-\|tRNA-glutamyl-Q(34)-synthetase-GluQRS	unknown	unknown	gnl\|CDD\|235573
NZ_CP045298.1\|WP_152382223.1\|4543758_4546287_+\|ATP-dependent-helicase-HrpB	unknown	unknown	gnl\|CDD\|273901
NZ_CP045298.1\|WP_025716886.1\|4526892_4527924_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NZ_CP045298.1\|WP_152381406.1\|4541429_4541597_+\|Spo0E-family-sporulation-regulatory-protein-aspartic-acid-phosphatase	unknown	unknown	gnl\|CDD\|378175
NZ_CP045298.1\|WP_152381398.1\|4520026_4522516_+\|CRISPR-associated-helicase-Cas3'	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP045298.1\|WP_152381396.1\|4515517_4516354_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045298.1\|WP_152381408.1\|4542025_4542400_+\|DUF1992-domain-containing-protein	unknown	unknown	gnl\|CDD\|182303
NZ_CP045298.1\|WP_025716884.1\|4525374_4526250_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	gnl\|CDD\|226175
NZ_CP045298.1\|WP_152378784.1\|4529289_4530407_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP045298.1\|WP_152381407.1\|4541707_4541902_+\|XRE-family-transcriptional-regulator	unknown	unknown	unknown
NZ_CP045298.1\|WP_152381405.1\|4539651_4541046_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|197775

Protein	Function_ID	Function_description	E-value
NZ_CP045298.1\|WP_152381400.1\|4523344_4525309_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|187887	cd09757, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Zn-finger domain containing protein, distant homologs of Cas8 proteins; signature gene for I-C subtype; also known as Csd1 family.	6.21097e-172
NZ_CP045298.1\|WP_152381403.1\|4531390_4532875_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	9.23074e-128
NZ_CP045298.1\|WP_152381399.1\|4522628_4523348_+\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|273847	TIGR01876, cas_Cas5d, CRISPR-associated protein Cas5, subtype I-C/DVULG. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum. This family belongs to a set of several Cas protein families, one each for a number of different CRISPR/Cas subtypes, that share a region of N-terminal sequence similarity modeled by TIGR02593. This family represents the Dvulg subtype of CRISPR/Cas locus.	1.76269e-95
NZ_CP045298.1\|WP_152382222.1\|4532984_4533914_+\|D-alanine--D-alanine-ligase	gnl\|CDD\|234948	PRK01372, ddl, D-alanine--D-alanine ligase; Reviewed.	2.43623e-144
NZ_CP045298.1\|WP_025716878.1\|4514752_4515505_+\|VWA-domain-containing-protein	gnl\|CDD\|238119	cd00198, vWFA, Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains.	7.72046e-08
NZ_CP045298.1\|WP_152381397.1\|4516619_4517429_+\|3-oxoacyl-ACP-reductase-FabG	gnl\|CDD\|235546	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG.	2.74028e-91
NZ_CP045298.1\|WP_152381404.1\|4533915_4535106_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|181082	PRK07682, PRK07682, aminotransferase.	0
NZ_CP045298.1\|WP_152381401.1\|4526236_4526896_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	7.96569e-27
NZ_CP045298.1\|WP_152381402.1\|4527934_4528225_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	9.97673e-31
NZ_CP045298.1\|WP_152381409.1\|4542464_4543460_-\|tRNA-glutamyl-Q(34)-synthetase-GluQRS	gnl\|CDD\|235573	PRK05710, PRK05710, tRNA glutamyl-Q(34) synthetase GluQRS.	4.61875e-115
NZ_CP045298.1\|WP_025716886.1\|4526892_4527924_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NZ_CP045298.1\|WP_152381406.1\|4541429_4541597_+\|Spo0E-family-sporulation-regulatory-protein-aspartic-acid-phosphatase	gnl\|CDD\|378175	pfam09388, SpoOE-like, Spo0E like sporulation regulatory protein. Spore formation is an extreme response to starvation and can also be a component of disease transmission. Sporulation is controlled by an expanded two-component system where starvation signals result in sensor kinase activation and phosphorylation of the master sporulation response regulator Spo0A. Phosphatases such as Spo0E dephosphorylate Spo0A thereby inhibiting sporulation. This is a family of Spo0E-like phosphatases. The structure of a Bacillus anthracis member of this family has revealed an anti-parallel alpha-helical structure.	8.57593e-08
NZ_CP045298.1\|WP_152381398.1\|4520026_4522516_+\|CRISPR-associated-helicase-Cas3'	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	7.82399e-72
NZ_CP045298.1\|WP_152381408.1\|4542025_4542400_+\|DUF1992-domain-containing-protein	gnl\|CDD\|182303	PRK10203, PRK10203, hypothetical protein; Provisional.	5.86244e-33
NZ_CP045298.1\|WP_025716884.1\|4525374_4526250_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|226175	COG3649, COG3649, CRISPR system related protein [Defense mechanisms].	9.72403e-128
NZ_CP045298.1\|WP_152378784.1\|4529289_4530407_+\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	2.29228e-43
NZ_CP045298.1\|WP_152382223.1\|4543758_4546287_+\|ATP-dependent-helicase-HrpB	gnl\|CDD\|273901	TIGR01970, ATP-dependent_RNA_helicase_HrpB, ATP-dependent helicase HrpB. This model represents HrpB, one of two related but uncharacterized DEAH-box ATP-dependent helicases in many Proteobacteria, but also in a few species of other lineages. The member from Rhizobium meliloti has been designated HelO. HrpB is typically about 800 residues in length, while its paralog HrpA (TIGR01967), also uncharacterized, is about 1300 amino acids long. Related characterized eukarotic proteins are RNA helicases associated with pre-mRNA processing. [Unknown function, Enzymes of unknown specificity].	0
NZ_CP045298.1\|WP_152381405.1\|4539651_4541046_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	4.79641e-05

>NZ_CP045298.1|WP_152381402.1|4527934_4528225_+|CRISPR-associated-endonuclease-Cas2
MLILITYDVSTVDREGRKRLAKVAKKCVDHGQRVQNSVFECILDSAQFRRLKYELEELIDKKEDSLRFYNLGDNYKKKVEHIGTKEAYDMESLLIL
>NZ_CP045298.1|WP_025716886.1|4526892_4527924_+|type-I-C-CRISPR-associated-endonuclease-Cas1
MKKLLNTLFVTMPDTYLSLDGENIVIKQEESILARYPLHNLEAVCTFGYSGVSPGLMGACATRNIDLTFMTRSGRFLARVTGESRGNVVLRKEQYRISDDDRRSALVARNMITGKIYNHKWILERATRDHQLRIDTDRLKKVSTSLTEIMKQVREVEELDILRGLEGTAAVQYNSVFDELILQQKDNFYFHGRHKRPPLDNVNALLSFAYTLLSNDMKSALEAVGLDAYVGFLHRDRPGRASLALDVMEELRGVYADRFVLSLINKKLIHGKGFYKKENGAVMMDDDTRKIVLKAWQERKQDKIIHPYLNEKMSWGLVPYSQALLLARHIRGDLDEYPPFLWK
>NZ_CP045298.1|WP_152381401.1|4526236_4526896_+|CRISPR-associated-protein-Cas4
MQGYNEEDYLLLSGIQHFNFCRRQWALIHIEQQWEENVRTIEGNHLHRKADQPMIREKRGDKLVVRALPVHSRELGITGICDVVEFARDPLGVPLAGEEGTYLPFPVEYKRGKPKRNDSDHAQLVAQVMCLEEMLVCEISKGYFYYDEIKHRVEVIITAADRERVRTSLQEMRHYFEQNHTPKAKAGPHCLSCSLHNICVPEILNKKSVSSFIESRLAE
>NZ_CP045298.1|WP_025716884.1|4525374_4526250_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MSILDHKIDFAVVLSVAKANPNGDPLNGNRPRQNYDGYGEISDVALKRKIRNRLQDMGESIFVQSNDRKLDSFHSLRERAEANPELGKIFKSKEGSSEEFAKMACQEWMDVRSFGQVFAFKAAGKGAGVSVGIRGPVSIHTATSVLPIDITSMQITKSVNSEPGSEKGSDTMGMKHRVDFGVYVFKGSINTQLAEKTGFTNEDAGKIREALISLFENDVSSARPDGSMEVHKVYWWEHNSKLGKYSSAKVHRSLEVKPKENVNAADKSFDTHYECILTPLEGLEVQEYAGL
>NZ_CP045298.1|WP_152381400.1|4523344_4525309_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MSWLLNLYETYKSNLGRVGVPEKKRDGREYTLLPISHTTQNAQIEVEITEQGDFHSARVLDKDEFSTLIPCTEKSASRAGSVVAPYPLHDKLSYVAGDFVAYGGKVKKEEPFATYIQQLEGWANSEYATPKLKSIYRYLSKRQLIKDLSDHSILYLDENQQLITKWDKKYERSPGEKPRIFTAVPGELESAFIRFNVYSPDKALTKVWLDTELYDSFISYYSQLLGEEDICYVTGKQLPSTDKHANKIRNSGDKAKLISANDTSGFTFRGRFADSHEAASISYEVSQKAHNALKWLIHRQGKIMDNRVFLVWGNDDPDVLSFTNNDNIFAMDFGPESSRPTAIKSHTNEELAFDLAKALSGYRNKLAVKSTSKANVNILVLDSATTGRMAVLYYRNLDKKLYFDKLIDWHSKCAWLHRYQKDEQGELLQFFGAPATKDIAFATYGPKANDKLVKGLMERMLPCIVDGRPVPQDIVRSATHRASNPVAMDKWEWEKTLSITCALINTQEGYNVSLDEEIRDRSYLFGRLLAIADVLERNALERSGQDRDKKRSTNAIRYMSVFSQHPERTWRTIQNALQPHQAKFGKQLNYYSIMIDEVASKIPFDEFNNEPLTGKYLLGFYSQRYEIYHNTDKKRHEGNNAGDENNQDDNIPGM
>NZ_CP045298.1|WP_152381399.1|4522628_4523348_+|type-I-C-CRISPR-associated-protein-Cas5
MRNSIEFRVYGDYALFTDPLTKLGGEKLTYNVPTYQALKGIVESIYWKPTITMVVDKVRVLNAIRMESKGIRPIEYGGGNTLANYTYLKDPCYEVQAHFIFNLHRPEMEYDRNENKHHNILKRSLLAGGRRDIFLGTRECQAYVEPCVFGEAPGFYDSYGEIHLGNMVHGINYPDETGRNQLEVRLWNPVMKDGVIEFIPPEKCPQVRVIAEMQPKRFDENNVQSADELLAEWEGWGMK
>NZ_CP045298.1|WP_152381398.1|4520026_4522516_+|CRISPR-associated-helicase-Cas3'
MEYIAHIRESDQVIQTVAEHLLETRQLAEAFGDKIGIRHITGLAGMLHDLGKYTEEFQHYIRLAVQNPDNPPKRGSVDHSTAGGKLLYKLFHIQPQGAFDQQDFMNKALLSEVVGNAIISHHAYLQDFLDPTLESKFLDRVRDRELEGFDHAVSLFYEQVMEKSAFFRYVNQAGTELAHYMKREDKTDIELKMMFLSKFVFSALIDADRTNTRCFEENNAKNEKNSNAPMNRQQLFQTYYERLMERINDLQSGENADTTINLLRKQMSEQCEQFADKPSGILTLSIPTGGGKTLASLRYALKHAVTFEKKHIIYVVPFTTIIEQNAQEVREIIRDDANLLEHHSNVVMNEVEDIDGEDHELEDVVVNTHQKLKLAKDNWDSPIIFTTMVQFLNVFYADGSRNIRRLHNLSESVIIFDEVQKVPTHCISLFNQALNFLKTYASSSIVLCTATQPELDFVHNKLDIEPDTEMVHDLDHVIEKFKRVEIVDKATDDTLDTEKLADFVEQILADESSILVILNTKAVVKNLYHRLTEGNGTIPVYHLSTSMCPAHRNRILEEVKQHLEHKKPVVCISTQLIEAGVDISFDCVIRSLAGMDSIAQAAGRCNRHGRDGTKQVYVIDHEEEDLKRLKEIKIGKEITRKMFIDLKRDETCYGGNVLSAQAMEIYFKKYYTELETDLNYFIPQLRRNMTELLSANRRENTYYRSYYDEKGTILPLFLANCYKTAAEHFQVIEDHTTAIIVPYGDGDKEGKEIIADLNGQQSIEDLTSLLRRAQQFTINIFHYEKKQLDQNKALVSFLDGKILALTEGAYHDSYGLNLENDSPHGGFFI
>NZ_CP045298.1|WP_152381397.1|4516619_4517429_+|3-oxoacyl-ACP-reductase-FabG
MSYTSAGNARFEGKTALITGAGSGIGKATAIQMAREGANVALFDVSNERILETEKEINAIREGSARAFDVDIADPVRVEKAVLEAVELFGGLHIVFANAGINGVVGPIEDLSIEDWRQTLSTNLDGTFLTVKYTVPHLKKNGGGSIIITSSINGNQRFTSFGMSAYSTSKAGQTGFAKMAALELAKFRIRVNVIYPGAISTNIDETTEKAERLKQITIPVKFPEGGQPLANGPGQPEQVADLVTFLASDHSRHITGAQIVIDGAESLLF
>NZ_CP045298.1|WP_152381396.1|4515517_4516354_+|hypothetical-protein
MNPLLSLLPASKRKGMNARLAQHFDYISSQTGDQPLSSHHSRFKCRYGYGRSAESASMGESGQDFAAVRIHKTVCCFVLCDGVGLSYRGDFAARYLGSSLLDWLEEGRDLSAEQLRMYLERLADTATVELDRQPLNHESGLMRSVLEDKRRQGSQSMYICGKIELPKRGARGRLRLAWQGDSRLRLWNGAEEISDLFAHTFSTAERWSTSRGPIGGKPHWYERSIPADMPMRLQVYSDGLSDLDPICEPVPDEQIQVLLDASHTGGLDDDAAFIELQW
>NZ_CP045298.1|WP_025716878.1|4514752_4515505_+|VWA-domain-containing-protein
MNYTIQASQRTPALIIYLIDISASMNMLMEGRRRIDVVYEAISLAIRQMVFRSTKGNRLTARYRIAILAYSDDVYDLLNGVKGIDEIAAIGSLPDLTPKRFSDSAKAFLQAERILQAELPGMQDCPAPLVCHMTDGVSTGDDPEPIAKRIMSMSVPDGNVLVENIFLSDRLLETPIQDPRRWKGLTHTTPLQDEHAVKLRNMSSVLPESYREMLFEADYQLGEGAIMMLPGTCAELVSIGFQMSAATPVR
>NZ_CP045298.1|WP_152378784.1|4529289_4530407_+|IS3-family-transposase
MPRQRRTFTADFKKQMVQLYDNGKPRAAIAREYELSPSALDRWIKQAQTSGSFAEKDNRTAEENELLALRKENERLKIENDIFKASRADHGTKVKIIKQNSDKYSVSALCEVLQIARSTFYYEAKEKDNEDEVTTAIVEIFHTNRKAYGTRKLKVKLQEQGYTVSRRRIGRIMKEQGLVSTYTIAQYKPHKTACNEATTANVLKREFDQTEAKRFVVSDLTYVKVQHKWHYICVLIDLFNREIIGHSAGPNKDAALISRAFATVEGDLSDIQWFHTDRGSEFRNQTMDELLETFDIGRSLSMKGCPYDNAVAEATYKVMKTEFVNQMNFQSLHHLKLELYDYVNWFNKHRIHGTLRYMTPVQYKAAALKKVV
>NZ_CP045298.1|WP_152381403.1|4531390_4532875_+|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MFQDFKLVSDRPVSIQVKEYVNRLIIKGVLQADQKLPSTREMSVLLKVSRNTVIAAYEGLEDDGFTYAIPGKGSYVAAMMGQSDVDNGGSDSSATWEIDWKMRMNEYAVSAVDLDMMKQGIRAQKGTISFTSIAPDEQLFDLGDVRRAFMDRMAIEGQVLLNYGYAKGYKPLIDYLMHYMENKGVDISGKDMLITGGFTEGFDIVLSALRPSGRRGAAICENPTHYTAIKNLKLQGFEITGIPMERDGIDVERLEAVLQTNSFDLAYLTPSYHNPTGIVMSPAKRSAVMKLMTRYQIPIIEDGFNEELRYSGAHVAPLIASAGHGNGVIYIGSFSKVLFPGLRVGWVLGDRALIDTLESIKRARTIHTSTIDQSILYQYMLNGNFDKHVKKARTEYKRKYELTKACCEAHLPETQVSGDGGLHLFLTFPAGVNTRQLLEDCTEQGVIFTPGDRFFIQEGEGTNTLRLGFSRVTDENIERGIQIIGKQARSFPKA
>NZ_CP045298.1|WP_152382222.1|4532984_4533914_+|D-alanine--D-alanine-ligase
MKIGVIMGGISSEREISLQTGQEMINHLDRSRYEVIPIVIEQRADLIVQVQQAGIDIALLALHGQYGEDGTVQGALETLGIPYTGSGVLASSLCMNKQLSKTLLKATGVHTPAGLCWQGMDDYDPQVVERLGYPVIVKPNTGGSSIGIQLVQNEKDLLPAIQEACSLDQAILIEPYYKGTEITCSIVDGEVLPIISISSARSKWFDYKAKYEVGGAKEEVIELPPVIEQRVREAALASYRLLQCKVYARVDMILCQDRPYVLEVNTLPGMTANSLLPKSAAAAGITFTQLLDHIIAISLHERKQEWGMA
>NZ_CP045298.1|WP_152381404.1|4533915_4535106_+|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MFIEKGIGRFVSSRVRDIRPSGIRAFFDLNAAGGEGDIIALGVGEPDFITPEKVREACIQALREGQTKYTSNAGLMELREEISAYFSGSFALSYDPEQEMIVTVGSSEAVDLALRAVIEPGDEVLIPAPSYIAYEPITHLHGGKIIEVAATAEEQFKLTPQALQAAITPHSKALMINYPCNPTGTVMTEQDWLPIAELIIQHNLVVISDEVYAELTYGRKHVSIASLPGMKERTIVISGFSKAFAMTGWRVGYACGPRELIAGMLKIHQYTAMCAPTIAQIAALESLRHGLAAKDEMMASYNERRKLFVAGLNAIGLACHEPEGAFYAFPSITSTGMSSEQFALRMLKEAKVALVPGHVFGSGGEGFIRCSYAASLVDLEKALGRMGRFMQVMQPV
>NZ_CP045298.1|WP_152381405.1|4539651_4541046_+|helix-turn-helix-domain-containing-protein
MKHTPTISAEFEAYLTQNDMTLAQFAEYSGVHQRTLSNWVTQHRPVSVQQLDRITVAMGLPEGYFYDLYIENYIINIPPNMRRIEPLLYRCAELDKLDAIRRMVGHIMDKLMYSPRLFEIAETLFAQGRRAAALPLYENVAEVEKYQHSERLAMCQYRIFTIQVGDDQSHNLKAATLFEPFVERLDEIDQLDALKDLANVYRSLRKWDRLDETARKMREKAKIQYTLKHQQKKPKGAELDKRLSRPMFVYITYSDLLCASVCEAQGDYQQALQYTYAYANLDWVIEKDESTQHWVNMFKYWAKGNTYVNKLLSGDISVLHDYVEYISVSSKTTEEDRVTQLLNIMMAANRYQVDVNDILQHFEIEIGSIIQQQPVNMYTYQVVPEQTTRFKYELAKYYLNSGNYSYGFNYLLDVLSKSLANNKESFFIRCIRLFEQFKQFADVRSFAKYESLASKGQRERLFYY
>NZ_CP045298.1|WP_152381406.1|4541429_4541597_+|Spo0E-family-sporulation-regulatory-protein-aspartic-acid-phosphatase
MLMNTGVTLLRVERARKRLYQVQKKYGFLTHPKVIEQSMKLDELLNQYQTCKMKS
>NZ_CP045298.1|WP_152381407.1|4541707_4541902_+|XRE-family-transcriptional-regulator
MNKRNPVTPFGWKIKQRLVEIQMDQRTFCDTYRVPASRLSNLIHGTRKAKKYRKQVSTLLGIEE
>NZ_CP045298.1|WP_152381408.1|4542025_4542400_+|DUF1992-domain-containing-protein
MGMFSRMAEQKIAEAMAKGEFDHLPGAGKPLVIEDLSHVPEELRMSYKLLKNAGILPEELQLQKECVQLRDLLHACHEAGEQQRISRRLTEKSLRLRMLLEERGLNTSSVFYEYESAVRKRLGE
>NZ_CP045298.1|WP_152381409.1|4542464_4543460_-|tRNA-glutamyl-Q(34)-synthetase-GluQRS
MELQAQPIRGRFAPTPSGWIHLGNARTALLSWLHVRSLGGTYVLRMEDIDMTRARSPLAQGIMEDLRWIGLEWDEGPDVGGSYGPYTQSQRLERFQAALEKLQGQDLLYPCFCSRADIVAAASAPHGLSGEGPAYSGTCRSLSPQEAEAKSQHKLPSLRFKVPQNQDSVISFQDQVAGNVTFGAAEGGDFIVKRADGMFSYQLAVVVDDADMHITDVLRGYDLLDSTPRQLLLYQALGLQPPRFAHVPLVLGPDGRRLAKRHGGVALRAMRRQGITPEAVIGWLAYFSGLLDSPEPVKAVDLIDGFHLDKLPNQPVILTKQFLRRLSELQR
>NZ_CP045298.1|WP_152382223.1|4543758_4546287_+|ATP-dependent-helicase-HrpB
MTDKQLPIIQVIPELKNTLQSQPAAVLIAQPGAGKTTVTPLELLHEPWLAGQKMIMLEPRRLAARAAAAQMAKALGEPTGKTVGYRVRMDTKVGPSTRIEVVTEGVLTRMLQHDQALEGVGLIIFDEFHERSLHADLGLALALQSQALLRPDLKILIMSATLEAEPVCGLLGDAPLLECPGTVFPVETFYRSKPASAILEDFTAETVEKALHAHEGDLLVFLPGAREIHRTERELASRNLPVHVKVIPLYGSMKLEQQDEAIRPSSLGSRKVVLATSIAESSLTIAGITVVIDSGLSRESVFSARTGMSRLTTVKVSKASADQRRGRAGRLQPGVCYRLWSAQEHAALPDASRPEIAAADLAPLALELAAWGVREPAELAWLDTPPEAAYRQATGLLRQLGCLHTAADGGAGGITAHGREVSALGVHPRLGHMLLRAAALGLAPAASRLAALLQERDPFRAHGGTDLRPRLDALREAAHARSTHSLLRTADDTVIRRIVQESRQLLATLPTAAAAQDEPDGSASCGLLLAFAYPDRIAQGRGDGRFLLSGGRGARLRQVEWMSRSSYLVAAEVDDEGADGVIQLAAPVELQELIEHCGELLLEKANVYWDNSASAVRARKVLQLGSLVVKETSYERPPAEEIAAALMQGVRERGLKLLSWNRQTLQLQARLIFMHFSAPEDWPDSSESALLDSLESWLLPFALGAKNMSDLQRLDGSELLLGRLNWEQRQQLEQEAPTHIRVPSGSRIPVDYSNPEAPALAVRLQELFGMRETPRIGRGRVPLVLHLLSPAQRPVQVTSDLSSFWSEAYFEVKKDLKGRYPKHYWPDDPLEAVPTSRAKPKR

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Crispr_ID: NZ_CP045298_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045298_9

4530428-4531201

TypeI

I-C

Consensus_repeat	Method
ATTTCAATCCACGCACTCATATAGAGTGCGAC	PILER-CR
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CRISPRCasFinder
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CRT

11 spacers

cas2,cas1,cas4,cas7,cas8c,cas5,cas3

The CRISPR arrays of NZ_CP045298_9

>merge|NZ_CP045298|9|4530428-4531201|PILER-CR,CRISPRCasFinder,CRT
GTCGCACTCTATATGAGTGCGTGGATTGAAATATCATCCCACTGGCCGGACACCTTGTTAAGCGCCGTCGCACTCTATATGAGTGCGTGGATTGAAATTCTCTCGCTTTGGTCGAGATGTGAAAAAGGTCGGCCAGGTCGCACTCTATATGAGTGCGTGGATTGAAATTTACAGTAATGTAAGTCGATAACCCAGTGAACGCTGTCGCACTCTATATGAGTGCGTGGATTGAAATCAGACGCGGCAACATACGAGTTCGCGAATGTACTTTCGTCGCACTCTATATGAGTGCGTGGATTGAAATTGTTCCAGATAATAAACATCTAACCTGGTACGTTTGGGTCGCACTCTATATGAGTGCGTGGATTGAAATTAGCGGGCATTGTTATCCTGGGGATACTCCAGATCATCGTCGCACTCTATATGAGTGCGTGGATTGAAATCATCTTCTTAACGTAGGCATCACCTTTACCCAGCTGTCGCACTCTATATGAGTGCGTGGATTGAAATATCTTATATCAGGATGGGAAAAGAATAACCAAGCTCGGGTCGCACTCTATATGAGTGCGTGGATTGAAATATTAGCTCGTCCGGTGGCGTTGGGCTGTGGATAATTGTCGCACTCTATATGAGTGCGTGGATTGAAATCATAGCTTTTCGTCCTCCAGGATACCCAATGATCTGGTCGCACTCTATATGAGTTCAAATTTGTCCAGCATGTGGAAGATTTGAAGGCCTTTAAGTCGCACTCCATGTGACAAATTGACGATGCGG

>NZ_CP045298|9|8|4530428-4531075|PILER-CR
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATCATCCCACTGGCCGGACACCTTGTTAAGCGCC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TCTCTCGCTTTGGTCGAGATGTGAAAAAGGTCGGCCAG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTACAGTAATGTAAGTCGATAACCCAGTGAACGCT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CAGACGCGGCAACATACGAGTTCGCGAATGTACTTTC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TGTTCCAGATAATAAACATCTAACCTGGTACGTTTGG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TAGCGGGCATTGTTATCCTGGGGATACTCCAGATCATC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CATCTTCTTAACGTAGGCATCACCTTTACCCAGCT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATCTTATATCAGGATGGGAAAAGAATAACCAAGCTCGG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATTAGCTCGTCCGGTGGCGTTGGGCTGTGGATAATT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT

>NZ_CP045298|9|9|4530428-4531075|CRISPRCasFinder
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATCATCCCACTGGCCGGACACCTTGTTAAGCGCC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TCTCTCGCTTTGGTCGAGATGTGAAAAAGGTCGGCCAG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTACAGTAATGTAAGTCGATAACCCAGTGAACGCT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CAGACGCGGCAACATACGAGTTCGCGAATGTACTTTC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TGTTCCAGATAATAAACATCTAACCTGGTACGTTTGG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TAGCGGGCATTGTTATCCTGGGGATACTCCAGATCATC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CATCTTCTTAACGTAGGCATCACCTTTACCCAGCT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATCTTATATCAGGATGGGAAAAGAATAACCAAGCTCGG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATTAGCTCGTCCGGTGGCGTTGGGCTGTGGATAATT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT

>NZ_CP045298|9|8|4530428-4531201|CRT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATCATCCCACTGGCCGGACACCTTGTTAAGCGCC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TCTCTCGCTTTGGTCGAGATGTGAAAAAGGTCGGCCAG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTACAGTAATGTAAGTCGATAACCCAGTGAACGCT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CAGACGCGGCAACATACGAGTTCGCGAATGTACTTTC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TGTTCCAGATAATAAACATCTAACCTGGTACGTTTGG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TAGCGGGCATTGTTATCCTGGGGATACTCCAGATCATC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CATCTTCTTAACGTAGGCATCACCTTTACCCAGCT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATCTTATATCAGGATGGGAAAAGAATAACCAAGCTCGG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATTAGCTCGTCCGGTGGCGTTGGGCTGTGGATAATT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CATAGCTTTTCGTCCTCCAGGATACCCAATGATCTG
GTCGCACTCTATATGAGTTCAAATTTGTCCAG	CATGTGGAAGATTTGAAGGCCTTTAA
GTCGCACTCCATGTGACAAATTGACGATGCGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045298.1\|WP_152381400.1\|4523344_4525309_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	pfam09709_cas8c_CAS-I-C	gnl\|CDD\|187887
NZ_CP045298.1\|WP_152381403.1\|4531390_4532875_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|224089
NZ_CP045298.1\|WP_152381399.1\|4522628_4523348_+\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|273847
NZ_CP045298.1\|WP_152382222.1\|4532984_4533914_+\|D-alanine--D-alanine-ligase	unknown	unknown	gnl\|CDD\|234948
NZ_CP045298.1\|WP_152378784.1\|4529289_4530407_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP045298.1\|WP_152381397.1\|4516619_4517429_+\|3-oxoacyl-ACP-reductase-FabG	unknown	unknown	gnl\|CDD\|235546
NZ_CP045298.1\|WP_152381404.1\|4533915_4535106_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|181082
NZ_CP045298.1\|WP_152381401.1\|4526236_4526896_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|273040
NZ_CP045298.1\|WP_152381410.1\|4547095_4548268_+\|acyltransferase-family-protein	unknown	unknown	gnl\|CDD\|376607
NZ_CP045298.1\|WP_152381402.1\|4527934_4528225_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP045298.1\|WP_152381409.1\|4542464_4543460_-\|tRNA-glutamyl-Q(34)-synthetase-GluQRS	unknown	unknown	gnl\|CDD\|235573
NZ_CP045298.1\|WP_152382223.1\|4543758_4546287_+\|ATP-dependent-helicase-HrpB	unknown	unknown	gnl\|CDD\|273901
NZ_CP045298.1\|WP_025716886.1\|4526892_4527924_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NZ_CP045298.1\|WP_152381406.1\|4541429_4541597_+\|Spo0E-family-sporulation-regulatory-protein-aspartic-acid-phosphatase	unknown	unknown	gnl\|CDD\|378175
NZ_CP045298.1\|WP_152381398.1\|4520026_4522516_+\|CRISPR-associated-helicase-Cas3'	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP045298.1\|WP_152381396.1\|4515517_4516354_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045298.1\|WP_152381408.1\|4542025_4542400_+\|DUF1992-domain-containing-protein	unknown	unknown	gnl\|CDD\|182303
NZ_CP045298.1\|WP_025716884.1\|4525374_4526250_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	gnl\|CDD\|226175
NZ_CP045298.1\|WP_152381407.1\|4541707_4541902_+\|XRE-family-transcriptional-regulator	unknown	unknown	unknown
NZ_CP045298.1\|WP_152381405.1\|4539651_4541046_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|197775

Protein	Function_ID	Function_description	E-value
NZ_CP045298.1\|WP_152381400.1\|4523344_4525309_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|187887	cd09757, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Zn-finger domain containing protein, distant homologs of Cas8 proteins; signature gene for I-C subtype; also known as Csd1 family.	6.21097e-172
NZ_CP045298.1\|WP_152381403.1\|4531390_4532875_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	9.23074e-128
NZ_CP045298.1\|WP_152381399.1\|4522628_4523348_+\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|273847	TIGR01876, cas_Cas5d, CRISPR-associated protein Cas5, subtype I-C/DVULG. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum. This family belongs to a set of several Cas protein families, one each for a number of different CRISPR/Cas subtypes, that share a region of N-terminal sequence similarity modeled by TIGR02593. This family represents the Dvulg subtype of CRISPR/Cas locus.	1.76269e-95
NZ_CP045298.1\|WP_152382222.1\|4532984_4533914_+\|D-alanine--D-alanine-ligase	gnl\|CDD\|234948	PRK01372, ddl, D-alanine--D-alanine ligase; Reviewed.	2.43623e-144
NZ_CP045298.1\|WP_152378784.1\|4529289_4530407_+\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	2.29228e-43
NZ_CP045298.1\|WP_152381397.1\|4516619_4517429_+\|3-oxoacyl-ACP-reductase-FabG	gnl\|CDD\|235546	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG.	2.74028e-91
NZ_CP045298.1\|WP_152381404.1\|4533915_4535106_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|181082	PRK07682, PRK07682, aminotransferase.	0
NZ_CP045298.1\|WP_152381401.1\|4526236_4526896_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	7.96569e-27
NZ_CP045298.1\|WP_152381410.1\|4547095_4548268_+\|acyltransferase-family-protein	gnl\|CDD\|376607	pfam01757, Acyl_transf_3, Acyltransferase family. This family includes a range of acyltransferase enzymes. This domain is found in many as yet uncharacterized C. elegans proteins and it is approximately 300 amino acids long.	6.868e-18
NZ_CP045298.1\|WP_152381402.1\|4527934_4528225_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	9.97673e-31
NZ_CP045298.1\|WP_152381409.1\|4542464_4543460_-\|tRNA-glutamyl-Q(34)-synthetase-GluQRS	gnl\|CDD\|235573	PRK05710, PRK05710, tRNA glutamyl-Q(34) synthetase GluQRS.	4.61875e-115
NZ_CP045298.1\|WP_025716886.1\|4526892_4527924_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NZ_CP045298.1\|WP_152381406.1\|4541429_4541597_+\|Spo0E-family-sporulation-regulatory-protein-aspartic-acid-phosphatase	gnl\|CDD\|378175	pfam09388, SpoOE-like, Spo0E like sporulation regulatory protein. Spore formation is an extreme response to starvation and can also be a component of disease transmission. Sporulation is controlled by an expanded two-component system where starvation signals result in sensor kinase activation and phosphorylation of the master sporulation response regulator Spo0A. Phosphatases such as Spo0E dephosphorylate Spo0A thereby inhibiting sporulation. This is a family of Spo0E-like phosphatases. The structure of a Bacillus anthracis member of this family has revealed an anti-parallel alpha-helical structure.	8.57593e-08
NZ_CP045298.1\|WP_152381398.1\|4520026_4522516_+\|CRISPR-associated-helicase-Cas3'	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	7.82399e-72
NZ_CP045298.1\|WP_152381408.1\|4542025_4542400_+\|DUF1992-domain-containing-protein	gnl\|CDD\|182303	PRK10203, PRK10203, hypothetical protein; Provisional.	5.86244e-33
NZ_CP045298.1\|WP_025716884.1\|4525374_4526250_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|226175	COG3649, COG3649, CRISPR system related protein [Defense mechanisms].	9.72403e-128
NZ_CP045298.1\|WP_152382223.1\|4543758_4546287_+\|ATP-dependent-helicase-HrpB	gnl\|CDD\|273901	TIGR01970, ATP-dependent_RNA_helicase_HrpB, ATP-dependent helicase HrpB. This model represents HrpB, one of two related but uncharacterized DEAH-box ATP-dependent helicases in many Proteobacteria, but also in a few species of other lineages. The member from Rhizobium meliloti has been designated HelO. HrpB is typically about 800 residues in length, while its paralog HrpA (TIGR01967), also uncharacterized, is about 1300 amino acids long. Related characterized eukarotic proteins are RNA helicases associated with pre-mRNA processing. [Unknown function, Enzymes of unknown specificity].	0
NZ_CP045298.1\|WP_152381405.1\|4539651_4541046_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	4.79641e-05

>NZ_CP045298.1|WP_152378784.1|4529289_4530407_+|IS3-family-transposase
MPRQRRTFTADFKKQMVQLYDNGKPRAAIAREYELSPSALDRWIKQAQTSGSFAEKDNRTAEENELLALRKENERLKIENDIFKASRADHGTKVKIIKQNSDKYSVSALCEVLQIARSTFYYEAKEKDNEDEVTTAIVEIFHTNRKAYGTRKLKVKLQEQGYTVSRRRIGRIMKEQGLVSTYTIAQYKPHKTACNEATTANVLKREFDQTEAKRFVVSDLTYVKVQHKWHYICVLIDLFNREIIGHSAGPNKDAALISRAFATVEGDLSDIQWFHTDRGSEFRNQTMDELLETFDIGRSLSMKGCPYDNAVAEATYKVMKTEFVNQMNFQSLHHLKLELYDYVNWFNKHRIHGTLRYMTPVQYKAAALKKVV
>NZ_CP045298.1|WP_152381402.1|4527934_4528225_+|CRISPR-associated-endonuclease-Cas2
MLILITYDVSTVDREGRKRLAKVAKKCVDHGQRVQNSVFECILDSAQFRRLKYELEELIDKKEDSLRFYNLGDNYKKKVEHIGTKEAYDMESLLIL
>NZ_CP045298.1|WP_025716886.1|4526892_4527924_+|type-I-C-CRISPR-associated-endonuclease-Cas1
MKKLLNTLFVTMPDTYLSLDGENIVIKQEESILARYPLHNLEAVCTFGYSGVSPGLMGACATRNIDLTFMTRSGRFLARVTGESRGNVVLRKEQYRISDDDRRSALVARNMITGKIYNHKWILERATRDHQLRIDTDRLKKVSTSLTEIMKQVREVEELDILRGLEGTAAVQYNSVFDELILQQKDNFYFHGRHKRPPLDNVNALLSFAYTLLSNDMKSALEAVGLDAYVGFLHRDRPGRASLALDVMEELRGVYADRFVLSLINKKLIHGKGFYKKENGAVMMDDDTRKIVLKAWQERKQDKIIHPYLNEKMSWGLVPYSQALLLARHIRGDLDEYPPFLWK
>NZ_CP045298.1|WP_152381401.1|4526236_4526896_+|CRISPR-associated-protein-Cas4
MQGYNEEDYLLLSGIQHFNFCRRQWALIHIEQQWEENVRTIEGNHLHRKADQPMIREKRGDKLVVRALPVHSRELGITGICDVVEFARDPLGVPLAGEEGTYLPFPVEYKRGKPKRNDSDHAQLVAQVMCLEEMLVCEISKGYFYYDEIKHRVEVIITAADRERVRTSLQEMRHYFEQNHTPKAKAGPHCLSCSLHNICVPEILNKKSVSSFIESRLAE
>NZ_CP045298.1|WP_025716884.1|4525374_4526250_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MSILDHKIDFAVVLSVAKANPNGDPLNGNRPRQNYDGYGEISDVALKRKIRNRLQDMGESIFVQSNDRKLDSFHSLRERAEANPELGKIFKSKEGSSEEFAKMACQEWMDVRSFGQVFAFKAAGKGAGVSVGIRGPVSIHTATSVLPIDITSMQITKSVNSEPGSEKGSDTMGMKHRVDFGVYVFKGSINTQLAEKTGFTNEDAGKIREALISLFENDVSSARPDGSMEVHKVYWWEHNSKLGKYSSAKVHRSLEVKPKENVNAADKSFDTHYECILTPLEGLEVQEYAGL
>NZ_CP045298.1|WP_152381400.1|4523344_4525309_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MSWLLNLYETYKSNLGRVGVPEKKRDGREYTLLPISHTTQNAQIEVEITEQGDFHSARVLDKDEFSTLIPCTEKSASRAGSVVAPYPLHDKLSYVAGDFVAYGGKVKKEEPFATYIQQLEGWANSEYATPKLKSIYRYLSKRQLIKDLSDHSILYLDENQQLITKWDKKYERSPGEKPRIFTAVPGELESAFIRFNVYSPDKALTKVWLDTELYDSFISYYSQLLGEEDICYVTGKQLPSTDKHANKIRNSGDKAKLISANDTSGFTFRGRFADSHEAASISYEVSQKAHNALKWLIHRQGKIMDNRVFLVWGNDDPDVLSFTNNDNIFAMDFGPESSRPTAIKSHTNEELAFDLAKALSGYRNKLAVKSTSKANVNILVLDSATTGRMAVLYYRNLDKKLYFDKLIDWHSKCAWLHRYQKDEQGELLQFFGAPATKDIAFATYGPKANDKLVKGLMERMLPCIVDGRPVPQDIVRSATHRASNPVAMDKWEWEKTLSITCALINTQEGYNVSLDEEIRDRSYLFGRLLAIADVLERNALERSGQDRDKKRSTNAIRYMSVFSQHPERTWRTIQNALQPHQAKFGKQLNYYSIMIDEVASKIPFDEFNNEPLTGKYLLGFYSQRYEIYHNTDKKRHEGNNAGDENNQDDNIPGM
>NZ_CP045298.1|WP_152381399.1|4522628_4523348_+|type-I-C-CRISPR-associated-protein-Cas5
MRNSIEFRVYGDYALFTDPLTKLGGEKLTYNVPTYQALKGIVESIYWKPTITMVVDKVRVLNAIRMESKGIRPIEYGGGNTLANYTYLKDPCYEVQAHFIFNLHRPEMEYDRNENKHHNILKRSLLAGGRRDIFLGTRECQAYVEPCVFGEAPGFYDSYGEIHLGNMVHGINYPDETGRNQLEVRLWNPVMKDGVIEFIPPEKCPQVRVIAEMQPKRFDENNVQSADELLAEWEGWGMK
>NZ_CP045298.1|WP_152381398.1|4520026_4522516_+|CRISPR-associated-helicase-Cas3'
MEYIAHIRESDQVIQTVAEHLLETRQLAEAFGDKIGIRHITGLAGMLHDLGKYTEEFQHYIRLAVQNPDNPPKRGSVDHSTAGGKLLYKLFHIQPQGAFDQQDFMNKALLSEVVGNAIISHHAYLQDFLDPTLESKFLDRVRDRELEGFDHAVSLFYEQVMEKSAFFRYVNQAGTELAHYMKREDKTDIELKMMFLSKFVFSALIDADRTNTRCFEENNAKNEKNSNAPMNRQQLFQTYYERLMERINDLQSGENADTTINLLRKQMSEQCEQFADKPSGILTLSIPTGGGKTLASLRYALKHAVTFEKKHIIYVVPFTTIIEQNAQEVREIIRDDANLLEHHSNVVMNEVEDIDGEDHELEDVVVNTHQKLKLAKDNWDSPIIFTTMVQFLNVFYADGSRNIRRLHNLSESVIIFDEVQKVPTHCISLFNQALNFLKTYASSSIVLCTATQPELDFVHNKLDIEPDTEMVHDLDHVIEKFKRVEIVDKATDDTLDTEKLADFVEQILADESSILVILNTKAVVKNLYHRLTEGNGTIPVYHLSTSMCPAHRNRILEEVKQHLEHKKPVVCISTQLIEAGVDISFDCVIRSLAGMDSIAQAAGRCNRHGRDGTKQVYVIDHEEEDLKRLKEIKIGKEITRKMFIDLKRDETCYGGNVLSAQAMEIYFKKYYTELETDLNYFIPQLRRNMTELLSANRRENTYYRSYYDEKGTILPLFLANCYKTAAEHFQVIEDHTTAIIVPYGDGDKEGKEIIADLNGQQSIEDLTSLLRRAQQFTINIFHYEKKQLDQNKALVSFLDGKILALTEGAYHDSYGLNLENDSPHGGFFI
>NZ_CP045298.1|WP_152381397.1|4516619_4517429_+|3-oxoacyl-ACP-reductase-FabG
MSYTSAGNARFEGKTALITGAGSGIGKATAIQMAREGANVALFDVSNERILETEKEINAIREGSARAFDVDIADPVRVEKAVLEAVELFGGLHIVFANAGINGVVGPIEDLSIEDWRQTLSTNLDGTFLTVKYTVPHLKKNGGGSIIITSSINGNQRFTSFGMSAYSTSKAGQTGFAKMAALELAKFRIRVNVIYPGAISTNIDETTEKAERLKQITIPVKFPEGGQPLANGPGQPEQVADLVTFLASDHSRHITGAQIVIDGAESLLF
>NZ_CP045298.1|WP_152381396.1|4515517_4516354_+|hypothetical-protein
MNPLLSLLPASKRKGMNARLAQHFDYISSQTGDQPLSSHHSRFKCRYGYGRSAESASMGESGQDFAAVRIHKTVCCFVLCDGVGLSYRGDFAARYLGSSLLDWLEEGRDLSAEQLRMYLERLADTATVELDRQPLNHESGLMRSVLEDKRRQGSQSMYICGKIELPKRGARGRLRLAWQGDSRLRLWNGAEEISDLFAHTFSTAERWSTSRGPIGGKPHWYERSIPADMPMRLQVYSDGLSDLDPICEPVPDEQIQVLLDASHTGGLDDDAAFIELQW
>NZ_CP045298.1|WP_152381403.1|4531390_4532875_+|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MFQDFKLVSDRPVSIQVKEYVNRLIIKGVLQADQKLPSTREMSVLLKVSRNTVIAAYEGLEDDGFTYAIPGKGSYVAAMMGQSDVDNGGSDSSATWEIDWKMRMNEYAVSAVDLDMMKQGIRAQKGTISFTSIAPDEQLFDLGDVRRAFMDRMAIEGQVLLNYGYAKGYKPLIDYLMHYMENKGVDISGKDMLITGGFTEGFDIVLSALRPSGRRGAAICENPTHYTAIKNLKLQGFEITGIPMERDGIDVERLEAVLQTNSFDLAYLTPSYHNPTGIVMSPAKRSAVMKLMTRYQIPIIEDGFNEELRYSGAHVAPLIASAGHGNGVIYIGSFSKVLFPGLRVGWVLGDRALIDTLESIKRARTIHTSTIDQSILYQYMLNGNFDKHVKKARTEYKRKYELTKACCEAHLPETQVSGDGGLHLFLTFPAGVNTRQLLEDCTEQGVIFTPGDRFFIQEGEGTNTLRLGFSRVTDENIERGIQIIGKQARSFPKA
>NZ_CP045298.1|WP_152382222.1|4532984_4533914_+|D-alanine--D-alanine-ligase
MKIGVIMGGISSEREISLQTGQEMINHLDRSRYEVIPIVIEQRADLIVQVQQAGIDIALLALHGQYGEDGTVQGALETLGIPYTGSGVLASSLCMNKQLSKTLLKATGVHTPAGLCWQGMDDYDPQVVERLGYPVIVKPNTGGSSIGIQLVQNEKDLLPAIQEACSLDQAILIEPYYKGTEITCSIVDGEVLPIISISSARSKWFDYKAKYEVGGAKEEVIELPPVIEQRVREAALASYRLLQCKVYARVDMILCQDRPYVLEVNTLPGMTANSLLPKSAAAAGITFTQLLDHIIAISLHERKQEWGMA
>NZ_CP045298.1|WP_152381404.1|4533915_4535106_+|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MFIEKGIGRFVSSRVRDIRPSGIRAFFDLNAAGGEGDIIALGVGEPDFITPEKVREACIQALREGQTKYTSNAGLMELREEISAYFSGSFALSYDPEQEMIVTVGSSEAVDLALRAVIEPGDEVLIPAPSYIAYEPITHLHGGKIIEVAATAEEQFKLTPQALQAAITPHSKALMINYPCNPTGTVMTEQDWLPIAELIIQHNLVVISDEVYAELTYGRKHVSIASLPGMKERTIVISGFSKAFAMTGWRVGYACGPRELIAGMLKIHQYTAMCAPTIAQIAALESLRHGLAAKDEMMASYNERRKLFVAGLNAIGLACHEPEGAFYAFPSITSTGMSSEQFALRMLKEAKVALVPGHVFGSGGEGFIRCSYAASLVDLEKALGRMGRFMQVMQPV
>NZ_CP045298.1|WP_152381405.1|4539651_4541046_+|helix-turn-helix-domain-containing-protein
MKHTPTISAEFEAYLTQNDMTLAQFAEYSGVHQRTLSNWVTQHRPVSVQQLDRITVAMGLPEGYFYDLYIENYIINIPPNMRRIEPLLYRCAELDKLDAIRRMVGHIMDKLMYSPRLFEIAETLFAQGRRAAALPLYENVAEVEKYQHSERLAMCQYRIFTIQVGDDQSHNLKAATLFEPFVERLDEIDQLDALKDLANVYRSLRKWDRLDETARKMREKAKIQYTLKHQQKKPKGAELDKRLSRPMFVYITYSDLLCASVCEAQGDYQQALQYTYAYANLDWVIEKDESTQHWVNMFKYWAKGNTYVNKLLSGDISVLHDYVEYISVSSKTTEEDRVTQLLNIMMAANRYQVDVNDILQHFEIEIGSIIQQQPVNMYTYQVVPEQTTRFKYELAKYYLNSGNYSYGFNYLLDVLSKSLANNKESFFIRCIRLFEQFKQFADVRSFAKYESLASKGQRERLFYY
>NZ_CP045298.1|WP_152381406.1|4541429_4541597_+|Spo0E-family-sporulation-regulatory-protein-aspartic-acid-phosphatase
MLMNTGVTLLRVERARKRLYQVQKKYGFLTHPKVIEQSMKLDELLNQYQTCKMKS
>NZ_CP045298.1|WP_152381407.1|4541707_4541902_+|XRE-family-transcriptional-regulator
MNKRNPVTPFGWKIKQRLVEIQMDQRTFCDTYRVPASRLSNLIHGTRKAKKYRKQVSTLLGIEE
>NZ_CP045298.1|WP_152381408.1|4542025_4542400_+|DUF1992-domain-containing-protein
MGMFSRMAEQKIAEAMAKGEFDHLPGAGKPLVIEDLSHVPEELRMSYKLLKNAGILPEELQLQKECVQLRDLLHACHEAGEQQRISRRLTEKSLRLRMLLEERGLNTSSVFYEYESAVRKRLGE
>NZ_CP045298.1|WP_152381409.1|4542464_4543460_-|tRNA-glutamyl-Q(34)-synthetase-GluQRS
MELQAQPIRGRFAPTPSGWIHLGNARTALLSWLHVRSLGGTYVLRMEDIDMTRARSPLAQGIMEDLRWIGLEWDEGPDVGGSYGPYTQSQRLERFQAALEKLQGQDLLYPCFCSRADIVAAASAPHGLSGEGPAYSGTCRSLSPQEAEAKSQHKLPSLRFKVPQNQDSVISFQDQVAGNVTFGAAEGGDFIVKRADGMFSYQLAVVVDDADMHITDVLRGYDLLDSTPRQLLLYQALGLQPPRFAHVPLVLGPDGRRLAKRHGGVALRAMRRQGITPEAVIGWLAYFSGLLDSPEPVKAVDLIDGFHLDKLPNQPVILTKQFLRRLSELQR
>NZ_CP045298.1|WP_152382223.1|4543758_4546287_+|ATP-dependent-helicase-HrpB
MTDKQLPIIQVIPELKNTLQSQPAAVLIAQPGAGKTTVTPLELLHEPWLAGQKMIMLEPRRLAARAAAAQMAKALGEPTGKTVGYRVRMDTKVGPSTRIEVVTEGVLTRMLQHDQALEGVGLIIFDEFHERSLHADLGLALALQSQALLRPDLKILIMSATLEAEPVCGLLGDAPLLECPGTVFPVETFYRSKPASAILEDFTAETVEKALHAHEGDLLVFLPGAREIHRTERELASRNLPVHVKVIPLYGSMKLEQQDEAIRPSSLGSRKVVLATSIAESSLTIAGITVVIDSGLSRESVFSARTGMSRLTTVKVSKASADQRRGRAGRLQPGVCYRLWSAQEHAALPDASRPEIAAADLAPLALELAAWGVREPAELAWLDTPPEAAYRQATGLLRQLGCLHTAADGGAGGITAHGREVSALGVHPRLGHMLLRAAALGLAPAASRLAALLQERDPFRAHGGTDLRPRLDALREAAHARSTHSLLRTADDTVIRRIVQESRQLLATLPTAAAAQDEPDGSASCGLLLAFAYPDRIAQGRGDGRFLLSGGRGARLRQVEWMSRSSYLVAAEVDDEGADGVIQLAAPVELQELIEHCGELLLEKANVYWDNSASAVRARKVLQLGSLVVKETSYERPPAEEIAAALMQGVRERGLKLLSWNRQTLQLQARLIFMHFSAPEDWPDSSESALLDSLESWLLPFALGAKNMSDLQRLDGSELLLGRLNWEQRQQLEQEAPTHIRVPSGSRIPVDYSNPEAPALAVRLQELFGMRETPRIGRGRVPLVLHLLSPAQRPVQVTSDLSSFWSEAYFEVKKDLKGRYPKHYWPDDPLEAVPTSRAKPKR
>NZ_CP045298.1|WP_152381410.1|4547095_4548268_+|acyltransferase-family-protein
MSQKERISEVALLRGLAFVAVVLQHSVAHYAVAQGARIQDGVLMTLLLLCSKFAVPVFVFITGMVLFYNYDGAFKYGTFLRKRFMDIIVPYIIWSLLYELGNQLVQSGGTIHPLDFLQKLLNGKSSYHLWYIVMIIQCYVLFPVFRYVVRRLSALLPSRWHPAALAGVGVLYFLLMFAVGPVYHAMDKLQLPVITSWFTLYADRNVIYFFFYFVLGAAAGMNVQRWNDWVTKAQMIYWPLFCVLTGYLLYEMTDLFQTPRGTVLSFNYLSLLRPIMAVFCVVSIFVAYRVAVWIAHKGGQVASMLTAIGTLSYGAYLMHAFMLRVTYYFDETLFADWSHVLRTLASFVLCVVFSIAGTWLLARMPLGKWIVGLRVRPRRAGGSSTLQKQA

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Crispr_ID: NZ_CP045298_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045298_10

4535602-4537240

TypeI

NA:I-C

Consensus_repeat	Method
ATTTCAATCCACGCACCCATATAGAGTGCGAC	PILER-CR
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CRISPRCasFinder
GTCGCACTCTATATGGGNTGCGTGGATTGAAAT	CRT

24 spacers

cas2,cas1,cas4,cas7,cas8c,cas5

The CRISPR arrays of NZ_CP045298_10

>merge|NZ_CP045298|10|4535602-4537240|PILER-CR,CRISPRCasFinder,CRT
GTCGCACTCTATATGGGTGCGTGGATTGAAATATTTTCCTTTTGGGACGGGATCGGTATCTACATGTCGTCGCACTCTATATGGGTGCGTGGATTGAAATGCCGCAGAGATGGCTTTTTCAGTGTCAGGTTTCAGTCGCACTCTATATGGGTGCGTGGATTGAAATACCAGTAAACGTGTGGTCTGCGATCCCTACGATAAGTCGCACTCTATATGGGTGCGTGGATTGAAATAACGTACTTAGCTCATTTTGAGATCGAGCCAGTACGTCGCACTCTATATGGGTGCGTGGATTGAAATCTCGTATAATTTCTCGTCGACTCCACCAGTGAAGTCGCACTCTATATGGGTGCGTGGATTGAAATTTGAGATACGATAACCAGCCTATCATAAAGCTAAAGTCGCACTCTATATGGGTGCGTGGATTGAAATTTGCACACGGGCCGACGTTTTCTCGGCCTGATCCTTGTCGCACTCTATATGGGTGCGTGGATTGAAATACTATTTCCCGGACCCGGACAACCCGGAGAAACGCCGCGTCGCACTCTATATGGGTGCGTGGATTGAAATCATTAGATCGCCATCCGATGAAACCATTAGGTCTGGTCGCACTCTATATGGGTGCGTGGATTGAAATATAAAAACTATGCTTGGTGTTCAAGCGGCGTACGTCGCACTCTATATGGGTGCGTGGATTGAAATTAATCCTAAGTCCCGAGAAACTTTGGCGAGTGAGGTCGCACTCTATATGGGTGCGTGGATTGAAATCACAACGATTCCCCATTATGAGGACAATGTGCAGGTCGCACTCTATATGGGTGCGTGGATTGAAATCTTTAGGCCGCGCGAAAGGTACTCGAAATTGTCGTCGCACTCTATATGGGTGCGTGGATTGAAATCCGAAGACGATCTATAATAAGGTTTGCCTCGTCCACGTCGCACTCTATATGGGTGCGTGGATTGAAATTTCCAGTTGGCTATGTCCGTCCGAAGTGATTTACTCGTCGCACTCTATATGGGTGCGTGGATTGAAATACTTAATGGAAGAACACGCAATATTGCTAAGCTATAACGTCGCACTCTATATGGGTGCGTGGATTGAAATCGCACAAACATTGTCGGATGAAGCACGCTTTAAGTCGCACTCTATATGGGTGCGTGGATTGAAATTCCAGCTGTTGCAGGCTCTGCAAACTGGTTGAGGGTCGCACTCTATATGGGTGCGTGGATTGAAATCTGTTATCCAATTTGTGCCGTCATGAGTAAACTTAGTCGCACTCTATATGGGTGCGTGGATTGAAATTGTACTGCAATCAGCGGAGAAACTGAAGCAAATATCGTCGCACTCTATATGAGTGCGTGGATTGAAATAATTGGAGTTTCCAGCAGCCAAGTACCCAGAAACAGTCGCACTCTATATGAGTGCGTGGATTGAAATATTAACACTGACTCCTTCATGCTCGTCTTCAGCGTCGCACTCTATATGAGTGCGTGGATTGAAATTATTCCTATTGTGGTATGGCGACAACTTGCAGAGTCGTCGCACTCTATATGAGTACGTGGATTGAAATTTTTGGCAATCACAAGTCACATTTTATAATCGGCCTGTCGTACTCTGTATGGAGTGTGTGGATTGGAA

>NZ_CP045298|10|9|4535602-4537172|PILER-CR
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	ATTTTCCTTTTGGGACGGGATCGGTATCTACATGTC
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	GCCGCAGAGATGGCTTTTTCAGTGTCAGGTTTCA
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	ACCAGTAAACGTGTGGTCTGCGATCCCTACGATAA
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	AACGTACTTAGCTCATTTTGAGATCGAGCCAGTAC
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	CTCGTATAATTTCTCGTCGACTCCACCAGTGAA
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	TTGAGATACGATAACCAGCCTATCATAAAGCTAAA
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	TTGCACACGGGCCGACGTTTTCTCGGCCTGATCCTT
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	ACTATTTCCCGGACCCGGACAACCCGGAGAAACGCCGC
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	CATTAGATCGCCATCCGATGAAACCATTAGGTCTG
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	ATAAAAACTATGCTTGGTGTTCAAGCGGCGTAC
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	TAATCCTAAGTCCCGAGAAACTTTGGCGAGTGAG
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	CACAACGATTCCCCATTATGAGGACAATGTGCAG
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	CTTTAGGCCGCGCGAAAGGTACTCGAAATTGTC
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	CCGAAGACGATCTATAATAAGGTTTGCCTCGTCCAC
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	TTCCAGTTGGCTATGTCCGTCCGAAGTGATTTACTC
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	ACTTAATGGAAGAACACGCAATATTGCTAAGCTATAAC
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	CGCACAAACATTGTCGGATGAAGCACGCTTTAA
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	TCCAGCTGTTGCAGGCTCTGCAAACTGGTTGAGG
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	CTGTTATCCAATTTGTGCCGTCATGAGTAAACTTA
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	TGTACTGCAATCAGCGGAGAAACTGAAGCAAATATC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	AATTGGAGTTTCCAGCAGCCAAGTACCCAGAAACA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATTAACACTGACTCCTTCATGCTCGTCTTCAGC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TATTCCTATTGTGGTATGGCGACAACTTGCAGAGTC
GTCGCACTCTATATGAGTACGTGGATTGAAAT

>NZ_CP045298|10|10|4535602-4537173|CRISPRCasFinder
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	ATTTTCCTTTTGGGACGGGATCGGTATCTACATGTC
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	GCCGCAGAGATGGCTTTTTCAGTGTCAGGTTTCA
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	ACCAGTAAACGTGTGGTCTGCGATCCCTACGATAA
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	AACGTACTTAGCTCATTTTGAGATCGAGCCAGTAC
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	CTCGTATAATTTCTCGTCGACTCCACCAGTGAA
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	TTGAGATACGATAACCAGCCTATCATAAAGCTAAA
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	TTGCACACGGGCCGACGTTTTCTCGGCCTGATCCTT
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	ACTATTTCCCGGACCCGGACAACCCGGAGAAACGCCGC
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	CATTAGATCGCCATCCGATGAAACCATTAGGTCTG
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	ATAAAAACTATGCTTGGTGTTCAAGCGGCGTAC
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	TAATCCTAAGTCCCGAGAAACTTTGGCGAGTGAG
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	CACAACGATTCCCCATTATGAGGACAATGTGCAG
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	CTTTAGGCCGCGCGAAAGGTACTCGAAATTGTC
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	CCGAAGACGATCTATAATAAGGTTTGCCTCGTCCAC
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	TTCCAGTTGGCTATGTCCGTCCGAAGTGATTTACTC
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	ACTTAATGGAAGAACACGCAATATTGCTAAGCTATAAC
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	CGCACAAACATTGTCGGATGAAGCACGCTTTAA
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	TCCAGCTGTTGCAGGCTCTGCAAACTGGTTGAGG
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	CTGTTATCCAATTTGTGCCGTCATGAGTAAACTTA
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	TGTACTGCAATCAGCGGAGAAACTGAAGCAAATATC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	AATTGGAGTTTCCAGCAGCCAAGTACCCAGAAACA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATTAACACTGACTCCTTCATGCTCGTCTTCAGC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TATTCCTATTGTGGTATGGCGACAACTTGCAGAGTC
GTCGCACTCTATATGAGTACGTGGATTGAAATT

>NZ_CP045298|10|9|4535602-4537240|CRT
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	ATTTTCCTTTTGGGACGGGATCGGTATCTACATGTC
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	GCCGCAGAGATGGCTTTTTCAGTGTCAGGTTTCA
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	ACCAGTAAACGTGTGGTCTGCGATCCCTACGATAA
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	AACGTACTTAGCTCATTTTGAGATCGAGCCAGTAC
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	CTCGTATAATTTCTCGTCGACTCCACCAGTGAA
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	TTGAGATACGATAACCAGCCTATCATAAAGCTAAA
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	TTGCACACGGGCCGACGTTTTCTCGGCCTGATCCTT
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	ACTATTTCCCGGACCCGGACAACCCGGAGAAACGCCGC
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	CATTAGATCGCCATCCGATGAAACCATTAGGTCTG
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	ATAAAAACTATGCTTGGTGTTCAAGCGGCGTAC
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	TAATCCTAAGTCCCGAGAAACTTTGGCGAGTGAG
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	CACAACGATTCCCCATTATGAGGACAATGTGCAG
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	CTTTAGGCCGCGCGAAAGGTACTCGAAATTGTC
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	CCGAAGACGATCTATAATAAGGTTTGCCTCGTCCAC
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	TTCCAGTTGGCTATGTCCGTCCGAAGTGATTTACTC
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	ACTTAATGGAAGAACACGCAATATTGCTAAGCTATAAC
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	CGCACAAACATTGTCGGATGAAGCACGCTTTAA
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	TCCAGCTGTTGCAGGCTCTGCAAACTGGTTGAGG
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	CTGTTATCCAATTTGTGCCGTCATGAGTAAACTTA
GTCGCACTCTATATGGGTGCGTGGATTGAAAT	TGTACTGCAATCAGCGGAGAAACTGAAGCAAATATC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	AATTGGAGTTTCCAGCAGCCAAGTACCCAGAAACA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATTAACACTGACTCCTTCATGCTCGTCTTCAGC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TATTCCTATTGTGGTATGGCGACAACTTGCAGAGTC
GTCGCACTCTATATGAGTACGTGGATTGAAAT	TTTTGGCAATCACAAGTCACATTTTATAATCGGCCT
GTCGTACTCTGTATGGAGTGTGTGGATTGGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045298.1\|WP_152381400.1\|4523344_4525309_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	pfam09709_cas8c_CAS-I-C	gnl\|CDD\|187887
NZ_CP045298.1\|WP_152381404.1\|4533915_4535106_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|181082
NZ_CP045298.1\|WP_152382224.1\|4549022_4550027_+\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NZ_CP045298.1\|WP_152381399.1\|4522628_4523348_+\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|273847
NZ_CP045298.1\|WP_152381406.1\|4541429_4541597_+\|Spo0E-family-sporulation-regulatory-protein-aspartic-acid-phosphatase	unknown	unknown	gnl\|CDD\|378175
NZ_CP045298.1\|WP_152378784.1\|4529289_4530407_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP045298.1\|WP_152382222.1\|4532984_4533914_+\|D-alanine--D-alanine-ligase	unknown	unknown	gnl\|CDD\|234948
NZ_CP045298.1\|WP_152381403.1\|4531390_4532875_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|224089
NZ_CP045298.1\|WP_152381401.1\|4526236_4526896_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|273040
NZ_CP045298.1\|WP_152381410.1\|4547095_4548268_+\|acyltransferase-family-protein	unknown	unknown	gnl\|CDD\|376607
NZ_CP045298.1\|WP_152381402.1\|4527934_4528225_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP045298.1\|WP_152381409.1\|4542464_4543460_-\|tRNA-glutamyl-Q(34)-synthetase-GluQRS	unknown	unknown	gnl\|CDD\|235573
NZ_CP045298.1\|WP_152381411.1\|4550167_4550551_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274340
NZ_CP045298.1\|WP_152382223.1\|4543758_4546287_+\|ATP-dependent-helicase-HrpB	unknown	unknown	gnl\|CDD\|273901
NZ_CP045298.1\|WP_025716886.1\|4526892_4527924_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NZ_CP045298.1\|WP_013310011.1\|4548640_4549003_+\|replication-termination-protein	unknown	unknown	gnl\|CDD\|376766
NZ_CP045298.1\|WP_152381408.1\|4542025_4542400_+\|DUF1992-domain-containing-protein	unknown	unknown	gnl\|CDD\|182303
NZ_CP045298.1\|WP_025716884.1\|4525374_4526250_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	gnl\|CDD\|226175
NZ_CP045298.1\|WP_152381407.1\|4541707_4541902_+\|XRE-family-transcriptional-regulator	unknown	unknown	unknown
NZ_CP045298.1\|WP_152381405.1\|4539651_4541046_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|197775

Protein	Function_ID	Function_description	E-value
NZ_CP045298.1\|WP_152381400.1\|4523344_4525309_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|187887	cd09757, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Zn-finger domain containing protein, distant homologs of Cas8 proteins; signature gene for I-C subtype; also known as Csd1 family.	6.21097e-172
NZ_CP045298.1\|WP_152381404.1\|4533915_4535106_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|181082	PRK07682, PRK07682, aminotransferase.	0
NZ_CP045298.1\|WP_152382224.1\|4549022_4550027_+\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	3.51143e-82
NZ_CP045298.1\|WP_152381399.1\|4522628_4523348_+\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|273847	TIGR01876, cas_Cas5d, CRISPR-associated protein Cas5, subtype I-C/DVULG. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum. This family belongs to a set of several Cas protein families, one each for a number of different CRISPR/Cas subtypes, that share a region of N-terminal sequence similarity modeled by TIGR02593. This family represents the Dvulg subtype of CRISPR/Cas locus.	1.76269e-95
NZ_CP045298.1\|WP_152381406.1\|4541429_4541597_+\|Spo0E-family-sporulation-regulatory-protein-aspartic-acid-phosphatase	gnl\|CDD\|378175	pfam09388, SpoOE-like, Spo0E like sporulation regulatory protein. Spore formation is an extreme response to starvation and can also be a component of disease transmission. Sporulation is controlled by an expanded two-component system where starvation signals result in sensor kinase activation and phosphorylation of the master sporulation response regulator Spo0A. Phosphatases such as Spo0E dephosphorylate Spo0A thereby inhibiting sporulation. This is a family of Spo0E-like phosphatases. The structure of a Bacillus anthracis member of this family has revealed an anti-parallel alpha-helical structure.	8.57593e-08
NZ_CP045298.1\|WP_152378784.1\|4529289_4530407_+\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	2.29228e-43
NZ_CP045298.1\|WP_152382222.1\|4532984_4533914_+\|D-alanine--D-alanine-ligase	gnl\|CDD\|234948	PRK01372, ddl, D-alanine--D-alanine ligase; Reviewed.	2.43623e-144
NZ_CP045298.1\|WP_152381403.1\|4531390_4532875_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	9.23074e-128
NZ_CP045298.1\|WP_152381401.1\|4526236_4526896_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	7.96569e-27
NZ_CP045298.1\|WP_152381410.1\|4547095_4548268_+\|acyltransferase-family-protein	gnl\|CDD\|376607	pfam01757, Acyl_transf_3, Acyltransferase family. This family includes a range of acyltransferase enzymes. This domain is found in many as yet uncharacterized C. elegans proteins and it is approximately 300 amino acids long.	6.868e-18
NZ_CP045298.1\|WP_152381402.1\|4527934_4528225_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	9.97673e-31
NZ_CP045298.1\|WP_152381409.1\|4542464_4543460_-\|tRNA-glutamyl-Q(34)-synthetase-GluQRS	gnl\|CDD\|235573	PRK05710, PRK05710, tRNA glutamyl-Q(34) synthetase GluQRS.	4.61875e-115
NZ_CP045298.1\|WP_152381411.1\|4550167_4550551_-\|hypothetical-protein	gnl\|CDD\|274340	TIGR02890, conserved_hypothetical_protein, regulatory protein, yteA family. Members of this predicted regulatory protein are found only in endospore-forming members of the Firmicutes group of bacteria, and in nearly every such species; Clostridium perfringens seems to be an exception. The member from Bacillus subtilis, the model system for the study of the sporulation program, has been designated both yteA and yzwB. Some (but not all) members of this family show a strong sequence match to Pfam family pfam01258 the C4-type zinc finger protein, DksA/TraR family, but only one of the four key Cys residues is conserved. All members of this protein family share an additional C-terminal domain. Smaller proteins from the proteobacteria with just the N-terminal domain, including DksA and DksA2 are RNA polymerase-binding regulatory proteins even if the Zn-binding site is not conserved. [Unknown function, General].	2.29679e-26
NZ_CP045298.1\|WP_025716886.1\|4526892_4527924_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NZ_CP045298.1\|WP_013310011.1\|4548640_4549003_+\|replication-termination-protein	gnl\|CDD\|376766	pfam02334, RTP, Replication terminator protein. The bacterial replication terminator protein (RTP) plays a role in the termination of DNA replication by impeding replication fork movement. Two RTP dimers bind to the two inverted repeat regions at the termination site.	1.76322e-55
NZ_CP045298.1\|WP_152381408.1\|4542025_4542400_+\|DUF1992-domain-containing-protein	gnl\|CDD\|182303	PRK10203, PRK10203, hypothetical protein; Provisional.	5.86244e-33
NZ_CP045298.1\|WP_025716884.1\|4525374_4526250_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|226175	COG3649, COG3649, CRISPR system related protein [Defense mechanisms].	9.72403e-128
NZ_CP045298.1\|WP_152382223.1\|4543758_4546287_+\|ATP-dependent-helicase-HrpB	gnl\|CDD\|273901	TIGR01970, ATP-dependent_RNA_helicase_HrpB, ATP-dependent helicase HrpB. This model represents HrpB, one of two related but uncharacterized DEAH-box ATP-dependent helicases in many Proteobacteria, but also in a few species of other lineages. The member from Rhizobium meliloti has been designated HelO. HrpB is typically about 800 residues in length, while its paralog HrpA (TIGR01967), also uncharacterized, is about 1300 amino acids long. Related characterized eukarotic proteins are RNA helicases associated with pre-mRNA processing. [Unknown function, Enzymes of unknown specificity].	0
NZ_CP045298.1\|WP_152381405.1\|4539651_4541046_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	4.79641e-05

>NZ_CP045298.1|WP_152381404.1|4533915_4535106_+|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MFIEKGIGRFVSSRVRDIRPSGIRAFFDLNAAGGEGDIIALGVGEPDFITPEKVREACIQALREGQTKYTSNAGLMELREEISAYFSGSFALSYDPEQEMIVTVGSSEAVDLALRAVIEPGDEVLIPAPSYIAYEPITHLHGGKIIEVAATAEEQFKLTPQALQAAITPHSKALMINYPCNPTGTVMTEQDWLPIAELIIQHNLVVISDEVYAELTYGRKHVSIASLPGMKERTIVISGFSKAFAMTGWRVGYACGPRELIAGMLKIHQYTAMCAPTIAQIAALESLRHGLAAKDEMMASYNERRKLFVAGLNAIGLACHEPEGAFYAFPSITSTGMSSEQFALRMLKEAKVALVPGHVFGSGGEGFIRCSYAASLVDLEKALGRMGRFMQVMQPV
>NZ_CP045298.1|WP_152382222.1|4532984_4533914_+|D-alanine--D-alanine-ligase
MKIGVIMGGISSEREISLQTGQEMINHLDRSRYEVIPIVIEQRADLIVQVQQAGIDIALLALHGQYGEDGTVQGALETLGIPYTGSGVLASSLCMNKQLSKTLLKATGVHTPAGLCWQGMDDYDPQVVERLGYPVIVKPNTGGSSIGIQLVQNEKDLLPAIQEACSLDQAILIEPYYKGTEITCSIVDGEVLPIISISSARSKWFDYKAKYEVGGAKEEVIELPPVIEQRVREAALASYRLLQCKVYARVDMILCQDRPYVLEVNTLPGMTANSLLPKSAAAAGITFTQLLDHIIAISLHERKQEWGMA
>NZ_CP045298.1|WP_152381403.1|4531390_4532875_+|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MFQDFKLVSDRPVSIQVKEYVNRLIIKGVLQADQKLPSTREMSVLLKVSRNTVIAAYEGLEDDGFTYAIPGKGSYVAAMMGQSDVDNGGSDSSATWEIDWKMRMNEYAVSAVDLDMMKQGIRAQKGTISFTSIAPDEQLFDLGDVRRAFMDRMAIEGQVLLNYGYAKGYKPLIDYLMHYMENKGVDISGKDMLITGGFTEGFDIVLSALRPSGRRGAAICENPTHYTAIKNLKLQGFEITGIPMERDGIDVERLEAVLQTNSFDLAYLTPSYHNPTGIVMSPAKRSAVMKLMTRYQIPIIEDGFNEELRYSGAHVAPLIASAGHGNGVIYIGSFSKVLFPGLRVGWVLGDRALIDTLESIKRARTIHTSTIDQSILYQYMLNGNFDKHVKKARTEYKRKYELTKACCEAHLPETQVSGDGGLHLFLTFPAGVNTRQLLEDCTEQGVIFTPGDRFFIQEGEGTNTLRLGFSRVTDENIERGIQIIGKQARSFPKA
>NZ_CP045298.1|WP_152378784.1|4529289_4530407_+|IS3-family-transposase
MPRQRRTFTADFKKQMVQLYDNGKPRAAIAREYELSPSALDRWIKQAQTSGSFAEKDNRTAEENELLALRKENERLKIENDIFKASRADHGTKVKIIKQNSDKYSVSALCEVLQIARSTFYYEAKEKDNEDEVTTAIVEIFHTNRKAYGTRKLKVKLQEQGYTVSRRRIGRIMKEQGLVSTYTIAQYKPHKTACNEATTANVLKREFDQTEAKRFVVSDLTYVKVQHKWHYICVLIDLFNREIIGHSAGPNKDAALISRAFATVEGDLSDIQWFHTDRGSEFRNQTMDELLETFDIGRSLSMKGCPYDNAVAEATYKVMKTEFVNQMNFQSLHHLKLELYDYVNWFNKHRIHGTLRYMTPVQYKAAALKKVV
>NZ_CP045298.1|WP_152381402.1|4527934_4528225_+|CRISPR-associated-endonuclease-Cas2
MLILITYDVSTVDREGRKRLAKVAKKCVDHGQRVQNSVFECILDSAQFRRLKYELEELIDKKEDSLRFYNLGDNYKKKVEHIGTKEAYDMESLLIL
>NZ_CP045298.1|WP_025716886.1|4526892_4527924_+|type-I-C-CRISPR-associated-endonuclease-Cas1
MKKLLNTLFVTMPDTYLSLDGENIVIKQEESILARYPLHNLEAVCTFGYSGVSPGLMGACATRNIDLTFMTRSGRFLARVTGESRGNVVLRKEQYRISDDDRRSALVARNMITGKIYNHKWILERATRDHQLRIDTDRLKKVSTSLTEIMKQVREVEELDILRGLEGTAAVQYNSVFDELILQQKDNFYFHGRHKRPPLDNVNALLSFAYTLLSNDMKSALEAVGLDAYVGFLHRDRPGRASLALDVMEELRGVYADRFVLSLINKKLIHGKGFYKKENGAVMMDDDTRKIVLKAWQERKQDKIIHPYLNEKMSWGLVPYSQALLLARHIRGDLDEYPPFLWK
>NZ_CP045298.1|WP_152381401.1|4526236_4526896_+|CRISPR-associated-protein-Cas4
MQGYNEEDYLLLSGIQHFNFCRRQWALIHIEQQWEENVRTIEGNHLHRKADQPMIREKRGDKLVVRALPVHSRELGITGICDVVEFARDPLGVPLAGEEGTYLPFPVEYKRGKPKRNDSDHAQLVAQVMCLEEMLVCEISKGYFYYDEIKHRVEVIITAADRERVRTSLQEMRHYFEQNHTPKAKAGPHCLSCSLHNICVPEILNKKSVSSFIESRLAE
>NZ_CP045298.1|WP_025716884.1|4525374_4526250_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MSILDHKIDFAVVLSVAKANPNGDPLNGNRPRQNYDGYGEISDVALKRKIRNRLQDMGESIFVQSNDRKLDSFHSLRERAEANPELGKIFKSKEGSSEEFAKMACQEWMDVRSFGQVFAFKAAGKGAGVSVGIRGPVSIHTATSVLPIDITSMQITKSVNSEPGSEKGSDTMGMKHRVDFGVYVFKGSINTQLAEKTGFTNEDAGKIREALISLFENDVSSARPDGSMEVHKVYWWEHNSKLGKYSSAKVHRSLEVKPKENVNAADKSFDTHYECILTPLEGLEVQEYAGL
>NZ_CP045298.1|WP_152381400.1|4523344_4525309_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MSWLLNLYETYKSNLGRVGVPEKKRDGREYTLLPISHTTQNAQIEVEITEQGDFHSARVLDKDEFSTLIPCTEKSASRAGSVVAPYPLHDKLSYVAGDFVAYGGKVKKEEPFATYIQQLEGWANSEYATPKLKSIYRYLSKRQLIKDLSDHSILYLDENQQLITKWDKKYERSPGEKPRIFTAVPGELESAFIRFNVYSPDKALTKVWLDTELYDSFISYYSQLLGEEDICYVTGKQLPSTDKHANKIRNSGDKAKLISANDTSGFTFRGRFADSHEAASISYEVSQKAHNALKWLIHRQGKIMDNRVFLVWGNDDPDVLSFTNNDNIFAMDFGPESSRPTAIKSHTNEELAFDLAKALSGYRNKLAVKSTSKANVNILVLDSATTGRMAVLYYRNLDKKLYFDKLIDWHSKCAWLHRYQKDEQGELLQFFGAPATKDIAFATYGPKANDKLVKGLMERMLPCIVDGRPVPQDIVRSATHRASNPVAMDKWEWEKTLSITCALINTQEGYNVSLDEEIRDRSYLFGRLLAIADVLERNALERSGQDRDKKRSTNAIRYMSVFSQHPERTWRTIQNALQPHQAKFGKQLNYYSIMIDEVASKIPFDEFNNEPLTGKYLLGFYSQRYEIYHNTDKKRHEGNNAGDENNQDDNIPGM
>NZ_CP045298.1|WP_152381399.1|4522628_4523348_+|type-I-C-CRISPR-associated-protein-Cas5
MRNSIEFRVYGDYALFTDPLTKLGGEKLTYNVPTYQALKGIVESIYWKPTITMVVDKVRVLNAIRMESKGIRPIEYGGGNTLANYTYLKDPCYEVQAHFIFNLHRPEMEYDRNENKHHNILKRSLLAGGRRDIFLGTRECQAYVEPCVFGEAPGFYDSYGEIHLGNMVHGINYPDETGRNQLEVRLWNPVMKDGVIEFIPPEKCPQVRVIAEMQPKRFDENNVQSADELLAEWEGWGMK
>NZ_CP045298.1|WP_152381405.1|4539651_4541046_+|helix-turn-helix-domain-containing-protein
MKHTPTISAEFEAYLTQNDMTLAQFAEYSGVHQRTLSNWVTQHRPVSVQQLDRITVAMGLPEGYFYDLYIENYIINIPPNMRRIEPLLYRCAELDKLDAIRRMVGHIMDKLMYSPRLFEIAETLFAQGRRAAALPLYENVAEVEKYQHSERLAMCQYRIFTIQVGDDQSHNLKAATLFEPFVERLDEIDQLDALKDLANVYRSLRKWDRLDETARKMREKAKIQYTLKHQQKKPKGAELDKRLSRPMFVYITYSDLLCASVCEAQGDYQQALQYTYAYANLDWVIEKDESTQHWVNMFKYWAKGNTYVNKLLSGDISVLHDYVEYISVSSKTTEEDRVTQLLNIMMAANRYQVDVNDILQHFEIEIGSIIQQQPVNMYTYQVVPEQTTRFKYELAKYYLNSGNYSYGFNYLLDVLSKSLANNKESFFIRCIRLFEQFKQFADVRSFAKYESLASKGQRERLFYY
>NZ_CP045298.1|WP_152381406.1|4541429_4541597_+|Spo0E-family-sporulation-regulatory-protein-aspartic-acid-phosphatase
MLMNTGVTLLRVERARKRLYQVQKKYGFLTHPKVIEQSMKLDELLNQYQTCKMKS
>NZ_CP045298.1|WP_152381407.1|4541707_4541902_+|XRE-family-transcriptional-regulator
MNKRNPVTPFGWKIKQRLVEIQMDQRTFCDTYRVPASRLSNLIHGTRKAKKYRKQVSTLLGIEE
>NZ_CP045298.1|WP_152381408.1|4542025_4542400_+|DUF1992-domain-containing-protein
MGMFSRMAEQKIAEAMAKGEFDHLPGAGKPLVIEDLSHVPEELRMSYKLLKNAGILPEELQLQKECVQLRDLLHACHEAGEQQRISRRLTEKSLRLRMLLEERGLNTSSVFYEYESAVRKRLGE
>NZ_CP045298.1|WP_152381409.1|4542464_4543460_-|tRNA-glutamyl-Q(34)-synthetase-GluQRS
MELQAQPIRGRFAPTPSGWIHLGNARTALLSWLHVRSLGGTYVLRMEDIDMTRARSPLAQGIMEDLRWIGLEWDEGPDVGGSYGPYTQSQRLERFQAALEKLQGQDLLYPCFCSRADIVAAASAPHGLSGEGPAYSGTCRSLSPQEAEAKSQHKLPSLRFKVPQNQDSVISFQDQVAGNVTFGAAEGGDFIVKRADGMFSYQLAVVVDDADMHITDVLRGYDLLDSTPRQLLLYQALGLQPPRFAHVPLVLGPDGRRLAKRHGGVALRAMRRQGITPEAVIGWLAYFSGLLDSPEPVKAVDLIDGFHLDKLPNQPVILTKQFLRRLSELQR
>NZ_CP045298.1|WP_152382223.1|4543758_4546287_+|ATP-dependent-helicase-HrpB
MTDKQLPIIQVIPELKNTLQSQPAAVLIAQPGAGKTTVTPLELLHEPWLAGQKMIMLEPRRLAARAAAAQMAKALGEPTGKTVGYRVRMDTKVGPSTRIEVVTEGVLTRMLQHDQALEGVGLIIFDEFHERSLHADLGLALALQSQALLRPDLKILIMSATLEAEPVCGLLGDAPLLECPGTVFPVETFYRSKPASAILEDFTAETVEKALHAHEGDLLVFLPGAREIHRTERELASRNLPVHVKVIPLYGSMKLEQQDEAIRPSSLGSRKVVLATSIAESSLTIAGITVVIDSGLSRESVFSARTGMSRLTTVKVSKASADQRRGRAGRLQPGVCYRLWSAQEHAALPDASRPEIAAADLAPLALELAAWGVREPAELAWLDTPPEAAYRQATGLLRQLGCLHTAADGGAGGITAHGREVSALGVHPRLGHMLLRAAALGLAPAASRLAALLQERDPFRAHGGTDLRPRLDALREAAHARSTHSLLRTADDTVIRRIVQESRQLLATLPTAAAAQDEPDGSASCGLLLAFAYPDRIAQGRGDGRFLLSGGRGARLRQVEWMSRSSYLVAAEVDDEGADGVIQLAAPVELQELIEHCGELLLEKANVYWDNSASAVRARKVLQLGSLVVKETSYERPPAEEIAAALMQGVRERGLKLLSWNRQTLQLQARLIFMHFSAPEDWPDSSESALLDSLESWLLPFALGAKNMSDLQRLDGSELLLGRLNWEQRQQLEQEAPTHIRVPSGSRIPVDYSNPEAPALAVRLQELFGMRETPRIGRGRVPLVLHLLSPAQRPVQVTSDLSSFWSEAYFEVKKDLKGRYPKHYWPDDPLEAVPTSRAKPKR
>NZ_CP045298.1|WP_152381410.1|4547095_4548268_+|acyltransferase-family-protein
MSQKERISEVALLRGLAFVAVVLQHSVAHYAVAQGARIQDGVLMTLLLLCSKFAVPVFVFITGMVLFYNYDGAFKYGTFLRKRFMDIIVPYIIWSLLYELGNQLVQSGGTIHPLDFLQKLLNGKSSYHLWYIVMIIQCYVLFPVFRYVVRRLSALLPSRWHPAALAGVGVLYFLLMFAVGPVYHAMDKLQLPVITSWFTLYADRNVIYFFFYFVLGAAAGMNVQRWNDWVTKAQMIYWPLFCVLTGYLLYEMTDLFQTPRGTVLSFNYLSLLRPIMAVFCVVSIFVAYRVAVWIAHKGGQVASMLTAIGTLSYGAYLMHAFMLRVTYYFDETLFADWSHVLRTLASFVLCVVFSIAGTWLLARMPLGKWIVGLRVRPRRAGGSSTLQKQA
>NZ_CP045298.1|WP_013310011.1|4548640_4549003_+|replication-termination-protein
MAFMISQRAFIKIYLITMVERHRGYGYQMLESMKDEFSGFGYVPPQSEVYRALHELVQEGVFYRTKRLKGTDPRVDFQEIVLYHFTDDGEEKARLYKKQVKADLDRCLGMLHKAEQDNYS
>NZ_CP045298.1|WP_152382224.1|4549022_4550027_+|Gfo/Idh/MocA-family-oxidoreductase
MGRKLKWGILGTAEIARIAVIPAVQQSERGEVLGIASRNADKAAEIAREFDIPKSYGSYEELLADPEIGAVYIPLPNHLHEEWTIRAAEAGKHVLCEKPSSLSSAGTSRMIEACKNAGVIFAEAFMYRYHPKHRRIKEIINSGEIGDIRGIHCTFTFNNADQANNVRFNKGMGGGSLYDVGVYPISAARMYLDREPEAVTVHALFSPEHDNVDMMASGLLEFPGGVNLTFDCGMWAANRSNMEILGSKGTIAMPKMFGWERTSVVPQIFVHVGSVTREERLKGFNSFELQVNAFAEAVLDGVPLPYEPEDAVSNMKVIDACIESAHSRKRVEIG
>NZ_CP045298.1|WP_152381411.1|4550167_4550551_-|hypothetical-protein
MNHLSESQLAELKHMLLEQINAALQRMKKGTYGICVESGEEIPFERLQAIPYTAYTVEHTPNRELSNDCPIEEQVMTPPPKGAGEVRQRNAGRFDDAGSWDAVEEYGTSNSPATAAKRDAASYDEGM

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Crispr_ID: NZ_CP045298_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045298_11

4537463-4539175

TypeI

I-C

Consensus_repeat	Method
ATTTCAATCCACGCACTCACATGGAGTGCGAC	PILER-CR
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CRISPRCasFinder
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	CRT

25 spacers

cas2,cas1,cas4,cas7,cas8c,cas5

The CRISPR arrays of NZ_CP045298_11

>merge|NZ_CP045298|11|4537463-4539175|PILER-CR,CRISPRCasFinder,CRT
GTCGCACTCCATGTGAGTGCGTGGATTGAAATAAACCTTTATACGATTTTATACAATCGAATGAAGTCGCACTCCATGTGAGTGCGTGGATTGAAATGTATGTGGGTGTGCACGGCTATGAGATGGGAGCCATCGTCGCACTCCATGTGAGTGCGTGGATTGAAATACGAAACGGATCATCGGCTAACGACCTACAAATATCGCGTCGCACTCCATGTGAGTGCGTGGATTGAAATTTAAATCAACCTCTCCTGAGCTGAGCATGTCAGGGTCGCACTCCATGTGAGTGCGTGGATTGAAATTTAGTTTAATTTAAATTTAATCTAAGAAATCATTTCGTCGCACTCCATGTGAGTGCGTGGATTGAAATATTTCGGCGTAACCGCAGGGCGTAAATTCTCGTCGCACTCCATGTGAGTGCGTGGATTGAAATTCCCCATCGCTATACTGCCAAAAGTCCCAGCTTGTGTCGCACTCCATGTGAGTGCGTGGATTGAAATTTCAAGGAAGTCGCTGTCCGAGATGCTTTCATTCAAGTCGCACTCCATGTGAGTGCGTGGATTGAAATAATCCTCACCTCGCTTAGTTCTACCCTCTCAATCAGGTCGCACTCCATGTGAGTGCGTGGATTGAAATCTCTCCCTTACCGTCCTTAGCCTTCCGATCGTTTTCGTCGCACTCCATGTGAGTGCGTGGATTGAAATTGATACCAACTTGCATGTAACTGCCGCCAAGCAAGTCGCACTCCATGTGAGTGCGTGGATTGAAATATGTATCTCTAAAAATTTGCACTTTTTTGATATGTCGCACTCCATGTGAGTGCGTGGATTGAAATATGAGTGCTATCAGCATAATCATGCCAAGCGCAGTCGCACTCCATGTGAGTGCGTGGATTGAAATTGGATTGCTGACCATCGCGGAGGTACGCAAGCAACGTCGCACTCCATGTGAGTGCGTGGATTGAAATCTGCTCCCATGCTGAAGCTCAGTAAGCCCTTTTGCAGTCGCACTCCATGTGAGTGCGTGGATTGAAATTACTTCCCACACTGCGGACATTGACCCCGAATAAGTCGCACTCCATGTGAGTGCGTGGATTGAAATTTTTACGAGATGCCGGAAATACCTGAGTTTACTGTCGCACTCCATGTGAGTGCGTGGATTGAAATCCATATGTTATCCGGATGCTGTGGCAGCATCGAGCAAGTCGCACTCCATGTGAGTGCGTGGATTGAAATAAATTCTGGTTGGTTATATTTTGTGCTGTCCCATGTCGCACTCCATGTGAGTGCGTGGATTGAAATAAACGGGTGTCCCAGTGTACGACGAGCGAATCGAGCGTCGCACTCCATGTGAGTGCGTGGATTGAAATTGACCATGAATCCGGTCAATACCATGACATATGCAGGTCGCACTCCATGTGAGTGCGTGGATTGAAATACCACGCCAGATGCAGGCGATAGGATACCTGGAACAGTCGCACTCCATGTGAGTGCGTGGATTGAAATAACTGCTGCAGGTGCATTAGCAGTTAAACGGACGAAGTCGCACTCCATGTGAGTGCGTGGATTGAAATTCTGCACCGGAATAATTAAGAGAATATTTAACGGAGTCGCGTCGCACTCCATGTGAGTGCGTGGATTGAAATTCCAAATATAACACAAAAGTTGGGAGGAAAGACTAAGTCGCACTCCATGTGAGTGCGTGGATTGAAAT

>NZ_CP045298|11|10|4537463-4539175|PILER-CR
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	AAACCTTTATACGATTTTATACAATCGAATGAA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	GTATGTGGGTGTGCACGGCTATGAGATGGGAGCCATC
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	ACGAAACGGATCATCGGCTAACGACCTACAAATATCGC
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TTAAATCAACCTCTCCTGAGCTGAGCATGTCAGG
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TTAGTTTAATTTAAATTTAATCTAAGAAATCATTTC
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	ATTTCGGCGTAACCGCAGGGCGTAAATTCTC
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TCCCCATCGCTATACTGCCAAAAGTCCCAGCTTGT
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TTCAAGGAAGTCGCTGTCCGAGATGCTTTCATTCAA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	AATCCTCACCTCGCTTAGTTCTACCCTCTCAATCAG
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	CTCTCCCTTACCGTCCTTAGCCTTCCGATCGTTTTC
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TGATACCAACTTGCATGTAACTGCCGCCAAGCAA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	ATGTATCTCTAAAAATTTGCACTTTTTTGATAT
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	ATGAGTGCTATCAGCATAATCATGCCAAGCGCA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TGGATTGCTGACCATCGCGGAGGTACGCAAGCAAC
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	CTGCTCCCATGCTGAAGCTCAGTAAGCCCTTTTGCA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TACTTCCCACACTGCGGACATTGACCCCGAATAA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TTTTACGAGATGCCGGAAATACCTGAGTTTACT
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	CCATATGTTATCCGGATGCTGTGGCAGCATCGAGCAA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	AAATTCTGGTTGGTTATATTTTGTGCTGTCCCAT
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	AAACGGGTGTCCCAGTGTACGACGAGCGAATCGAGC
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TGACCATGAATCCGGTCAATACCATGACATATGCAG
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	ACCACGCCAGATGCAGGCGATAGGATACCTGGAACA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	AACTGCTGCAGGTGCATTAGCAGTTAAACGGACGAA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TCTGCACCGGAATAATTAAGAGAATATTTAACGGAGTCGC
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TCCAAATATAACACAAAAGTTGGGAGGAAAGACTAA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT

>NZ_CP045298|11|11|4537463-4539175|CRISPRCasFinder
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	AAACCTTTATACGATTTTATACAATCGAATGAA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	GTATGTGGGTGTGCACGGCTATGAGATGGGAGCCATC
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	ACGAAACGGATCATCGGCTAACGACCTACAAATATCGC
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TTAAATCAACCTCTCCTGAGCTGAGCATGTCAGG
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TTAGTTTAATTTAAATTTAATCTAAGAAATCATTTC
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	ATTTCGGCGTAACCGCAGGGCGTAAATTCTC
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TCCCCATCGCTATACTGCCAAAAGTCCCAGCTTGT
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TTCAAGGAAGTCGCTGTCCGAGATGCTTTCATTCAA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	AATCCTCACCTCGCTTAGTTCTACCCTCTCAATCAG
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	CTCTCCCTTACCGTCCTTAGCCTTCCGATCGTTTTC
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TGATACCAACTTGCATGTAACTGCCGCCAAGCAA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	ATGTATCTCTAAAAATTTGCACTTTTTTGATAT
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	ATGAGTGCTATCAGCATAATCATGCCAAGCGCA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TGGATTGCTGACCATCGCGGAGGTACGCAAGCAAC
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	CTGCTCCCATGCTGAAGCTCAGTAAGCCCTTTTGCA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TACTTCCCACACTGCGGACATTGACCCCGAATAA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TTTTACGAGATGCCGGAAATACCTGAGTTTACT
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	CCATATGTTATCCGGATGCTGTGGCAGCATCGAGCAA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	AAATTCTGGTTGGTTATATTTTGTGCTGTCCCAT
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	AAACGGGTGTCCCAGTGTACGACGAGCGAATCGAGC
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TGACCATGAATCCGGTCAATACCATGACATATGCAG
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	ACCACGCCAGATGCAGGCGATAGGATACCTGGAACA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	AACTGCTGCAGGTGCATTAGCAGTTAAACGGACGAA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TCTGCACCGGAATAATTAAGAGAATATTTAACGGAGTCGC
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TCCAAATATAACACAAAAGTTGGGAGGAAAGACTAA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT

>NZ_CP045298|11|10|4537463-4539175|CRT
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	AAACCTTTATACGATTTTATACAATCGAATGAA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	GTATGTGGGTGTGCACGGCTATGAGATGGGAGCCATC
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	ACGAAACGGATCATCGGCTAACGACCTACAAATATCGC
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TTAAATCAACCTCTCCTGAGCTGAGCATGTCAGG
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TTAGTTTAATTTAAATTTAATCTAAGAAATCATTTC
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	ATTTCGGCGTAACCGCAGGGCGTAAATTCTC
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TCCCCATCGCTATACTGCCAAAAGTCCCAGCTTGT
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TTCAAGGAAGTCGCTGTCCGAGATGCTTTCATTCAA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	AATCCTCACCTCGCTTAGTTCTACCCTCTCAATCAG
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	CTCTCCCTTACCGTCCTTAGCCTTCCGATCGTTTTC
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TGATACCAACTTGCATGTAACTGCCGCCAAGCAA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	ATGTATCTCTAAAAATTTGCACTTTTTTGATAT
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	ATGAGTGCTATCAGCATAATCATGCCAAGCGCA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TGGATTGCTGACCATCGCGGAGGTACGCAAGCAAC
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	CTGCTCCCATGCTGAAGCTCAGTAAGCCCTTTTGCA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TACTTCCCACACTGCGGACATTGACCCCGAATAA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TTTTACGAGATGCCGGAAATACCTGAGTTTACT
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	CCATATGTTATCCGGATGCTGTGGCAGCATCGAGCAA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	AAATTCTGGTTGGTTATATTTTGTGCTGTCCCAT
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	AAACGGGTGTCCCAGTGTACGACGAGCGAATCGAGC
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TGACCATGAATCCGGTCAATACCATGACATATGCAG
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	ACCACGCCAGATGCAGGCGATAGGATACCTGGAACA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	AACTGCTGCAGGTGCATTAGCAGTTAAACGGACGAA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TCTGCACCGGAATAATTAAGAGAATATTTAACGGAGTCGC
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TCCAAATATAACACAAAAGTTGGGAGGAAAGACTAA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045298.1\|WP_152381400.1\|4523344_4525309_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	pfam09709_cas8c_CAS-I-C	gnl\|CDD\|187887
NZ_CP045298.1\|WP_152381404.1\|4533915_4535106_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|181082
NZ_CP045298.1\|WP_152382224.1\|4549022_4550027_+\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NZ_CP045298.1\|WP_152381399.1\|4522628_4523348_+\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|273847
NZ_CP045298.1\|WP_152381406.1\|4541429_4541597_+\|Spo0E-family-sporulation-regulatory-protein-aspartic-acid-phosphatase	unknown	unknown	gnl\|CDD\|378175
NZ_CP045298.1\|WP_152378784.1\|4529289_4530407_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP045298.1\|WP_152382222.1\|4532984_4533914_+\|D-alanine--D-alanine-ligase	unknown	unknown	gnl\|CDD\|234948
NZ_CP045298.1\|WP_152381403.1\|4531390_4532875_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|224089
NZ_CP045298.1\|WP_152381401.1\|4526236_4526896_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|273040
NZ_CP045298.1\|WP_152381410.1\|4547095_4548268_+\|acyltransferase-family-protein	unknown	unknown	gnl\|CDD\|376607
NZ_CP045298.1\|WP_152381402.1\|4527934_4528225_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP045298.1\|WP_152381409.1\|4542464_4543460_-\|tRNA-glutamyl-Q(34)-synthetase-GluQRS	unknown	unknown	gnl\|CDD\|235573
NZ_CP045298.1\|WP_152381411.1\|4550167_4550551_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274340
NZ_CP045298.1\|WP_152382223.1\|4543758_4546287_+\|ATP-dependent-helicase-HrpB	unknown	unknown	gnl\|CDD\|273901
NZ_CP045298.1\|WP_025716886.1\|4526892_4527924_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NZ_CP045298.1\|WP_013310011.1\|4548640_4549003_+\|replication-termination-protein	unknown	unknown	gnl\|CDD\|376766
NZ_CP045298.1\|WP_152381408.1\|4542025_4542400_+\|DUF1992-domain-containing-protein	unknown	unknown	gnl\|CDD\|182303
NZ_CP045298.1\|WP_025716884.1\|4525374_4526250_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	gnl\|CDD\|226175
NZ_CP045298.1\|WP_152381407.1\|4541707_4541902_+\|XRE-family-transcriptional-regulator	unknown	unknown	unknown
NZ_CP045298.1\|WP_152381405.1\|4539651_4541046_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|197775

Protein	Function_ID	Function_description	E-value
NZ_CP045298.1\|WP_152381400.1\|4523344_4525309_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|187887	cd09757, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Zn-finger domain containing protein, distant homologs of Cas8 proteins; signature gene for I-C subtype; also known as Csd1 family.	6.21097e-172
NZ_CP045298.1\|WP_152381404.1\|4533915_4535106_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|181082	PRK07682, PRK07682, aminotransferase.	0
NZ_CP045298.1\|WP_152382224.1\|4549022_4550027_+\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	3.51143e-82
NZ_CP045298.1\|WP_152381399.1\|4522628_4523348_+\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|273847	TIGR01876, cas_Cas5d, CRISPR-associated protein Cas5, subtype I-C/DVULG. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum. This family belongs to a set of several Cas protein families, one each for a number of different CRISPR/Cas subtypes, that share a region of N-terminal sequence similarity modeled by TIGR02593. This family represents the Dvulg subtype of CRISPR/Cas locus.	1.76269e-95
NZ_CP045298.1\|WP_152381406.1\|4541429_4541597_+\|Spo0E-family-sporulation-regulatory-protein-aspartic-acid-phosphatase	gnl\|CDD\|378175	pfam09388, SpoOE-like, Spo0E like sporulation regulatory protein. Spore formation is an extreme response to starvation and can also be a component of disease transmission. Sporulation is controlled by an expanded two-component system where starvation signals result in sensor kinase activation and phosphorylation of the master sporulation response regulator Spo0A. Phosphatases such as Spo0E dephosphorylate Spo0A thereby inhibiting sporulation. This is a family of Spo0E-like phosphatases. The structure of a Bacillus anthracis member of this family has revealed an anti-parallel alpha-helical structure.	8.57593e-08
NZ_CP045298.1\|WP_152378784.1\|4529289_4530407_+\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	2.29228e-43
NZ_CP045298.1\|WP_152382222.1\|4532984_4533914_+\|D-alanine--D-alanine-ligase	gnl\|CDD\|234948	PRK01372, ddl, D-alanine--D-alanine ligase; Reviewed.	2.43623e-144
NZ_CP045298.1\|WP_152381403.1\|4531390_4532875_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	9.23074e-128
NZ_CP045298.1\|WP_152381401.1\|4526236_4526896_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	7.96569e-27
NZ_CP045298.1\|WP_152381410.1\|4547095_4548268_+\|acyltransferase-family-protein	gnl\|CDD\|376607	pfam01757, Acyl_transf_3, Acyltransferase family. This family includes a range of acyltransferase enzymes. This domain is found in many as yet uncharacterized C. elegans proteins and it is approximately 300 amino acids long.	6.868e-18
NZ_CP045298.1\|WP_152381402.1\|4527934_4528225_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	9.97673e-31
NZ_CP045298.1\|WP_152381409.1\|4542464_4543460_-\|tRNA-glutamyl-Q(34)-synthetase-GluQRS	gnl\|CDD\|235573	PRK05710, PRK05710, tRNA glutamyl-Q(34) synthetase GluQRS.	4.61875e-115
NZ_CP045298.1\|WP_152381411.1\|4550167_4550551_-\|hypothetical-protein	gnl\|CDD\|274340	TIGR02890, conserved_hypothetical_protein, regulatory protein, yteA family. Members of this predicted regulatory protein are found only in endospore-forming members of the Firmicutes group of bacteria, and in nearly every such species; Clostridium perfringens seems to be an exception. The member from Bacillus subtilis, the model system for the study of the sporulation program, has been designated both yteA and yzwB. Some (but not all) members of this family show a strong sequence match to Pfam family pfam01258 the C4-type zinc finger protein, DksA/TraR family, but only one of the four key Cys residues is conserved. All members of this protein family share an additional C-terminal domain. Smaller proteins from the proteobacteria with just the N-terminal domain, including DksA and DksA2 are RNA polymerase-binding regulatory proteins even if the Zn-binding site is not conserved. [Unknown function, General].	2.29679e-26
NZ_CP045298.1\|WP_025716886.1\|4526892_4527924_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NZ_CP045298.1\|WP_013310011.1\|4548640_4549003_+\|replication-termination-protein	gnl\|CDD\|376766	pfam02334, RTP, Replication terminator protein. The bacterial replication terminator protein (RTP) plays a role in the termination of DNA replication by impeding replication fork movement. Two RTP dimers bind to the two inverted repeat regions at the termination site.	1.76322e-55
NZ_CP045298.1\|WP_152381408.1\|4542025_4542400_+\|DUF1992-domain-containing-protein	gnl\|CDD\|182303	PRK10203, PRK10203, hypothetical protein; Provisional.	5.86244e-33
NZ_CP045298.1\|WP_025716884.1\|4525374_4526250_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|226175	COG3649, COG3649, CRISPR system related protein [Defense mechanisms].	9.72403e-128
NZ_CP045298.1\|WP_152382223.1\|4543758_4546287_+\|ATP-dependent-helicase-HrpB	gnl\|CDD\|273901	TIGR01970, ATP-dependent_RNA_helicase_HrpB, ATP-dependent helicase HrpB. This model represents HrpB, one of two related but uncharacterized DEAH-box ATP-dependent helicases in many Proteobacteria, but also in a few species of other lineages. The member from Rhizobium meliloti has been designated HelO. HrpB is typically about 800 residues in length, while its paralog HrpA (TIGR01967), also uncharacterized, is about 1300 amino acids long. Related characterized eukarotic proteins are RNA helicases associated with pre-mRNA processing. [Unknown function, Enzymes of unknown specificity].	0
NZ_CP045298.1\|WP_152381405.1\|4539651_4541046_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	4.79641e-05

>NZ_CP045298.1|WP_152381404.1|4533915_4535106_+|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MFIEKGIGRFVSSRVRDIRPSGIRAFFDLNAAGGEGDIIALGVGEPDFITPEKVREACIQALREGQTKYTSNAGLMELREEISAYFSGSFALSYDPEQEMIVTVGSSEAVDLALRAVIEPGDEVLIPAPSYIAYEPITHLHGGKIIEVAATAEEQFKLTPQALQAAITPHSKALMINYPCNPTGTVMTEQDWLPIAELIIQHNLVVISDEVYAELTYGRKHVSIASLPGMKERTIVISGFSKAFAMTGWRVGYACGPRELIAGMLKIHQYTAMCAPTIAQIAALESLRHGLAAKDEMMASYNERRKLFVAGLNAIGLACHEPEGAFYAFPSITSTGMSSEQFALRMLKEAKVALVPGHVFGSGGEGFIRCSYAASLVDLEKALGRMGRFMQVMQPV
>NZ_CP045298.1|WP_152382222.1|4532984_4533914_+|D-alanine--D-alanine-ligase
MKIGVIMGGISSEREISLQTGQEMINHLDRSRYEVIPIVIEQRADLIVQVQQAGIDIALLALHGQYGEDGTVQGALETLGIPYTGSGVLASSLCMNKQLSKTLLKATGVHTPAGLCWQGMDDYDPQVVERLGYPVIVKPNTGGSSIGIQLVQNEKDLLPAIQEACSLDQAILIEPYYKGTEITCSIVDGEVLPIISISSARSKWFDYKAKYEVGGAKEEVIELPPVIEQRVREAALASYRLLQCKVYARVDMILCQDRPYVLEVNTLPGMTANSLLPKSAAAAGITFTQLLDHIIAISLHERKQEWGMA
>NZ_CP045298.1|WP_152381403.1|4531390_4532875_+|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MFQDFKLVSDRPVSIQVKEYVNRLIIKGVLQADQKLPSTREMSVLLKVSRNTVIAAYEGLEDDGFTYAIPGKGSYVAAMMGQSDVDNGGSDSSATWEIDWKMRMNEYAVSAVDLDMMKQGIRAQKGTISFTSIAPDEQLFDLGDVRRAFMDRMAIEGQVLLNYGYAKGYKPLIDYLMHYMENKGVDISGKDMLITGGFTEGFDIVLSALRPSGRRGAAICENPTHYTAIKNLKLQGFEITGIPMERDGIDVERLEAVLQTNSFDLAYLTPSYHNPTGIVMSPAKRSAVMKLMTRYQIPIIEDGFNEELRYSGAHVAPLIASAGHGNGVIYIGSFSKVLFPGLRVGWVLGDRALIDTLESIKRARTIHTSTIDQSILYQYMLNGNFDKHVKKARTEYKRKYELTKACCEAHLPETQVSGDGGLHLFLTFPAGVNTRQLLEDCTEQGVIFTPGDRFFIQEGEGTNTLRLGFSRVTDENIERGIQIIGKQARSFPKA
>NZ_CP045298.1|WP_152378784.1|4529289_4530407_+|IS3-family-transposase
MPRQRRTFTADFKKQMVQLYDNGKPRAAIAREYELSPSALDRWIKQAQTSGSFAEKDNRTAEENELLALRKENERLKIENDIFKASRADHGTKVKIIKQNSDKYSVSALCEVLQIARSTFYYEAKEKDNEDEVTTAIVEIFHTNRKAYGTRKLKVKLQEQGYTVSRRRIGRIMKEQGLVSTYTIAQYKPHKTACNEATTANVLKREFDQTEAKRFVVSDLTYVKVQHKWHYICVLIDLFNREIIGHSAGPNKDAALISRAFATVEGDLSDIQWFHTDRGSEFRNQTMDELLETFDIGRSLSMKGCPYDNAVAEATYKVMKTEFVNQMNFQSLHHLKLELYDYVNWFNKHRIHGTLRYMTPVQYKAAALKKVV
>NZ_CP045298.1|WP_152381402.1|4527934_4528225_+|CRISPR-associated-endonuclease-Cas2
MLILITYDVSTVDREGRKRLAKVAKKCVDHGQRVQNSVFECILDSAQFRRLKYELEELIDKKEDSLRFYNLGDNYKKKVEHIGTKEAYDMESLLIL
>NZ_CP045298.1|WP_025716886.1|4526892_4527924_+|type-I-C-CRISPR-associated-endonuclease-Cas1
MKKLLNTLFVTMPDTYLSLDGENIVIKQEESILARYPLHNLEAVCTFGYSGVSPGLMGACATRNIDLTFMTRSGRFLARVTGESRGNVVLRKEQYRISDDDRRSALVARNMITGKIYNHKWILERATRDHQLRIDTDRLKKVSTSLTEIMKQVREVEELDILRGLEGTAAVQYNSVFDELILQQKDNFYFHGRHKRPPLDNVNALLSFAYTLLSNDMKSALEAVGLDAYVGFLHRDRPGRASLALDVMEELRGVYADRFVLSLINKKLIHGKGFYKKENGAVMMDDDTRKIVLKAWQERKQDKIIHPYLNEKMSWGLVPYSQALLLARHIRGDLDEYPPFLWK
>NZ_CP045298.1|WP_152381401.1|4526236_4526896_+|CRISPR-associated-protein-Cas4
MQGYNEEDYLLLSGIQHFNFCRRQWALIHIEQQWEENVRTIEGNHLHRKADQPMIREKRGDKLVVRALPVHSRELGITGICDVVEFARDPLGVPLAGEEGTYLPFPVEYKRGKPKRNDSDHAQLVAQVMCLEEMLVCEISKGYFYYDEIKHRVEVIITAADRERVRTSLQEMRHYFEQNHTPKAKAGPHCLSCSLHNICVPEILNKKSVSSFIESRLAE
>NZ_CP045298.1|WP_025716884.1|4525374_4526250_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MSILDHKIDFAVVLSVAKANPNGDPLNGNRPRQNYDGYGEISDVALKRKIRNRLQDMGESIFVQSNDRKLDSFHSLRERAEANPELGKIFKSKEGSSEEFAKMACQEWMDVRSFGQVFAFKAAGKGAGVSVGIRGPVSIHTATSVLPIDITSMQITKSVNSEPGSEKGSDTMGMKHRVDFGVYVFKGSINTQLAEKTGFTNEDAGKIREALISLFENDVSSARPDGSMEVHKVYWWEHNSKLGKYSSAKVHRSLEVKPKENVNAADKSFDTHYECILTPLEGLEVQEYAGL
>NZ_CP045298.1|WP_152381400.1|4523344_4525309_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MSWLLNLYETYKSNLGRVGVPEKKRDGREYTLLPISHTTQNAQIEVEITEQGDFHSARVLDKDEFSTLIPCTEKSASRAGSVVAPYPLHDKLSYVAGDFVAYGGKVKKEEPFATYIQQLEGWANSEYATPKLKSIYRYLSKRQLIKDLSDHSILYLDENQQLITKWDKKYERSPGEKPRIFTAVPGELESAFIRFNVYSPDKALTKVWLDTELYDSFISYYSQLLGEEDICYVTGKQLPSTDKHANKIRNSGDKAKLISANDTSGFTFRGRFADSHEAASISYEVSQKAHNALKWLIHRQGKIMDNRVFLVWGNDDPDVLSFTNNDNIFAMDFGPESSRPTAIKSHTNEELAFDLAKALSGYRNKLAVKSTSKANVNILVLDSATTGRMAVLYYRNLDKKLYFDKLIDWHSKCAWLHRYQKDEQGELLQFFGAPATKDIAFATYGPKANDKLVKGLMERMLPCIVDGRPVPQDIVRSATHRASNPVAMDKWEWEKTLSITCALINTQEGYNVSLDEEIRDRSYLFGRLLAIADVLERNALERSGQDRDKKRSTNAIRYMSVFSQHPERTWRTIQNALQPHQAKFGKQLNYYSIMIDEVASKIPFDEFNNEPLTGKYLLGFYSQRYEIYHNTDKKRHEGNNAGDENNQDDNIPGM
>NZ_CP045298.1|WP_152381399.1|4522628_4523348_+|type-I-C-CRISPR-associated-protein-Cas5
MRNSIEFRVYGDYALFTDPLTKLGGEKLTYNVPTYQALKGIVESIYWKPTITMVVDKVRVLNAIRMESKGIRPIEYGGGNTLANYTYLKDPCYEVQAHFIFNLHRPEMEYDRNENKHHNILKRSLLAGGRRDIFLGTRECQAYVEPCVFGEAPGFYDSYGEIHLGNMVHGINYPDETGRNQLEVRLWNPVMKDGVIEFIPPEKCPQVRVIAEMQPKRFDENNVQSADELLAEWEGWGMK
>NZ_CP045298.1|WP_152381405.1|4539651_4541046_+|helix-turn-helix-domain-containing-protein
MKHTPTISAEFEAYLTQNDMTLAQFAEYSGVHQRTLSNWVTQHRPVSVQQLDRITVAMGLPEGYFYDLYIENYIINIPPNMRRIEPLLYRCAELDKLDAIRRMVGHIMDKLMYSPRLFEIAETLFAQGRRAAALPLYENVAEVEKYQHSERLAMCQYRIFTIQVGDDQSHNLKAATLFEPFVERLDEIDQLDALKDLANVYRSLRKWDRLDETARKMREKAKIQYTLKHQQKKPKGAELDKRLSRPMFVYITYSDLLCASVCEAQGDYQQALQYTYAYANLDWVIEKDESTQHWVNMFKYWAKGNTYVNKLLSGDISVLHDYVEYISVSSKTTEEDRVTQLLNIMMAANRYQVDVNDILQHFEIEIGSIIQQQPVNMYTYQVVPEQTTRFKYELAKYYLNSGNYSYGFNYLLDVLSKSLANNKESFFIRCIRLFEQFKQFADVRSFAKYESLASKGQRERLFYY
>NZ_CP045298.1|WP_152381406.1|4541429_4541597_+|Spo0E-family-sporulation-regulatory-protein-aspartic-acid-phosphatase
MLMNTGVTLLRVERARKRLYQVQKKYGFLTHPKVIEQSMKLDELLNQYQTCKMKS
>NZ_CP045298.1|WP_152381407.1|4541707_4541902_+|XRE-family-transcriptional-regulator
MNKRNPVTPFGWKIKQRLVEIQMDQRTFCDTYRVPASRLSNLIHGTRKAKKYRKQVSTLLGIEE
>NZ_CP045298.1|WP_152381408.1|4542025_4542400_+|DUF1992-domain-containing-protein
MGMFSRMAEQKIAEAMAKGEFDHLPGAGKPLVIEDLSHVPEELRMSYKLLKNAGILPEELQLQKECVQLRDLLHACHEAGEQQRISRRLTEKSLRLRMLLEERGLNTSSVFYEYESAVRKRLGE
>NZ_CP045298.1|WP_152381409.1|4542464_4543460_-|tRNA-glutamyl-Q(34)-synthetase-GluQRS
MELQAQPIRGRFAPTPSGWIHLGNARTALLSWLHVRSLGGTYVLRMEDIDMTRARSPLAQGIMEDLRWIGLEWDEGPDVGGSYGPYTQSQRLERFQAALEKLQGQDLLYPCFCSRADIVAAASAPHGLSGEGPAYSGTCRSLSPQEAEAKSQHKLPSLRFKVPQNQDSVISFQDQVAGNVTFGAAEGGDFIVKRADGMFSYQLAVVVDDADMHITDVLRGYDLLDSTPRQLLLYQALGLQPPRFAHVPLVLGPDGRRLAKRHGGVALRAMRRQGITPEAVIGWLAYFSGLLDSPEPVKAVDLIDGFHLDKLPNQPVILTKQFLRRLSELQR
>NZ_CP045298.1|WP_152382223.1|4543758_4546287_+|ATP-dependent-helicase-HrpB
MTDKQLPIIQVIPELKNTLQSQPAAVLIAQPGAGKTTVTPLELLHEPWLAGQKMIMLEPRRLAARAAAAQMAKALGEPTGKTVGYRVRMDTKVGPSTRIEVVTEGVLTRMLQHDQALEGVGLIIFDEFHERSLHADLGLALALQSQALLRPDLKILIMSATLEAEPVCGLLGDAPLLECPGTVFPVETFYRSKPASAILEDFTAETVEKALHAHEGDLLVFLPGAREIHRTERELASRNLPVHVKVIPLYGSMKLEQQDEAIRPSSLGSRKVVLATSIAESSLTIAGITVVIDSGLSRESVFSARTGMSRLTTVKVSKASADQRRGRAGRLQPGVCYRLWSAQEHAALPDASRPEIAAADLAPLALELAAWGVREPAELAWLDTPPEAAYRQATGLLRQLGCLHTAADGGAGGITAHGREVSALGVHPRLGHMLLRAAALGLAPAASRLAALLQERDPFRAHGGTDLRPRLDALREAAHARSTHSLLRTADDTVIRRIVQESRQLLATLPTAAAAQDEPDGSASCGLLLAFAYPDRIAQGRGDGRFLLSGGRGARLRQVEWMSRSSYLVAAEVDDEGADGVIQLAAPVELQELIEHCGELLLEKANVYWDNSASAVRARKVLQLGSLVVKETSYERPPAEEIAAALMQGVRERGLKLLSWNRQTLQLQARLIFMHFSAPEDWPDSSESALLDSLESWLLPFALGAKNMSDLQRLDGSELLLGRLNWEQRQQLEQEAPTHIRVPSGSRIPVDYSNPEAPALAVRLQELFGMRETPRIGRGRVPLVLHLLSPAQRPVQVTSDLSSFWSEAYFEVKKDLKGRYPKHYWPDDPLEAVPTSRAKPKR
>NZ_CP045298.1|WP_152381410.1|4547095_4548268_+|acyltransferase-family-protein
MSQKERISEVALLRGLAFVAVVLQHSVAHYAVAQGARIQDGVLMTLLLLCSKFAVPVFVFITGMVLFYNYDGAFKYGTFLRKRFMDIIVPYIIWSLLYELGNQLVQSGGTIHPLDFLQKLLNGKSSYHLWYIVMIIQCYVLFPVFRYVVRRLSALLPSRWHPAALAGVGVLYFLLMFAVGPVYHAMDKLQLPVITSWFTLYADRNVIYFFFYFVLGAAAGMNVQRWNDWVTKAQMIYWPLFCVLTGYLLYEMTDLFQTPRGTVLSFNYLSLLRPIMAVFCVVSIFVAYRVAVWIAHKGGQVASMLTAIGTLSYGAYLMHAFMLRVTYYFDETLFADWSHVLRTLASFVLCVVFSIAGTWLLARMPLGKWIVGLRVRPRRAGGSSTLQKQA
>NZ_CP045298.1|WP_013310011.1|4548640_4549003_+|replication-termination-protein
MAFMISQRAFIKIYLITMVERHRGYGYQMLESMKDEFSGFGYVPPQSEVYRALHELVQEGVFYRTKRLKGTDPRVDFQEIVLYHFTDDGEEKARLYKKQVKADLDRCLGMLHKAEQDNYS
>NZ_CP045298.1|WP_152382224.1|4549022_4550027_+|Gfo/Idh/MocA-family-oxidoreductase
MGRKLKWGILGTAEIARIAVIPAVQQSERGEVLGIASRNADKAAEIAREFDIPKSYGSYEELLADPEIGAVYIPLPNHLHEEWTIRAAEAGKHVLCEKPSSLSSAGTSRMIEACKNAGVIFAEAFMYRYHPKHRRIKEIINSGEIGDIRGIHCTFTFNNADQANNVRFNKGMGGGSLYDVGVYPISAARMYLDREPEAVTVHALFSPEHDNVDMMASGLLEFPGGVNLTFDCGMWAANRSNMEILGSKGTIAMPKMFGWERTSVVPQIFVHVGSVTREERLKGFNSFELQVNAFAEAVLDGVPLPYEPEDAVSNMKVIDACIESAHSRKRVEIG
>NZ_CP045298.1|WP_152381411.1|4550167_4550551_-|hypothetical-protein
MNHLSESQLAELKHMLLEQINAALQRMKKGTYGICVESGEEIPFERLQAIPYTAYTVEHTPNRELSNDCPIEEQVMTPPPKGAGEVRQRNAGRFDDAGSWDAVEEYGTSNSPATAAKRDAASYDEGM

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Crispr_ID: NZ_CP045298_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045298_12

5028930-5029160

Orphan

Consensus_repeat	Method
GTTTCAATCCACACACTCATATAGAGTGCGAC	PILER-CR
GTTTCAATCCACACACTCATATAGAGTGCGAC	CRISPRCasFinder
GTTTCAATCCACACACTCATATAGAGTGCGAC	CRT

3 spacers

The CRISPR arrays of NZ_CP045298_12

>merge|NZ_CP045298|12|5028930-5029160|PILER-CR,CRISPRCasFinder,CRT
GTTTCAATCCACACACTCATATAGAGTGCGACAGACGATTATACCACAAAGCTAGTTTTGGAAAGCGTTTCAATCCACACACTCATATAGAGTGCGACTCTATTCACCGGCGGATGCCGCGCATGTTGGAGCTGTTTCAATCCACACACTCATATAGAGTGCGACTATGTTCTATAAAACTGGTGCCGAAATTGGTGCCGTTTCAATCCACACACTCATATAGAGTGCGAC

>NZ_CP045298|12|11|5028930-5029160|PILER-CR
GTTTCAATCCACACACTCATATAGAGTGCGAC	AGACGATTATACCACAAAGCTAGTTTTGGAAAGC
GTTTCAATCCACACACTCATATAGAGTGCGAC	TCTATTCACCGGCGGATGCCGCGCATGTTGGAGCT
GTTTCAATCCACACACTCATATAGAGTGCGAC	TATGTTCTATAAAACTGGTGCCGAAATTGGTGCC
GTTTCAATCCACACACTCATATAGAGTGCGAC

>NZ_CP045298|12|12|5028930-5029160|CRISPRCasFinder
GTTTCAATCCACACACTCATATAGAGTGCGAC	AGACGATTATACCACAAAGCTAGTTTTGGAAAGC
GTTTCAATCCACACACTCATATAGAGTGCGAC	TCTATTCACCGGCGGATGCCGCGCATGTTGGAGCT
GTTTCAATCCACACACTCATATAGAGTGCGAC	TATGTTCTATAAAACTGGTGCCGAAATTGGTGCC
GTTTCAATCCACACACTCATATAGAGTGCGAC

>NZ_CP045298|12|11|5028930-5029160|CRT
GTTTCAATCCACACACTCATATAGAGTGCGAC	AGACGATTATACCACAAAGCTAGTTTTGGAAAGC
GTTTCAATCCACACACTCATATAGAGTGCGAC	TCTATTCACCGGCGGATGCCGCGCATGTTGGAGCT
GTTTCAATCCACACACTCATATAGAGTGCGAC	TATGTTCTATAAAACTGGTGCCGAAATTGGTGCC
GTTTCAATCCACACACTCATATAGAGTGCGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045298.1\|WP_152381674.1\|5031445_5031778_+\|transposase	unknown	unknown	gnl\|CDD\|225511
NZ_CP045298.1\|WP_152382248.1\|5034982_5035693_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|378924
NZ_CP045298.1\|WP_152381679.1\|5037818_5039120_+\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|225281
NZ_CP045298.1\|WP_152381672.1\|5029242_5030006_-\|IS5-family-transposase	unknown	unknown	gnl\|CDD\|379129
NZ_CP045298.1\|WP_152381673.1\|5030794_5031070_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045298.1\|WP_167518757.1\|5018251_5018428_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379402
NZ_CP045298.1\|WP_152381676.1\|5032861_5033146_+\|transposase	unknown	unknown	gnl\|CDD\|366690
NZ_CP045298.1\|WP_152381666.1\|5019125_5019530_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274791
NZ_CP045298.1\|WP_167518759.1\|5019586_5019841_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045298.1\|WP_152380558.1\|5036525_5036837_+\|transposase	unknown	unknown	gnl\|CDD\|366690
NZ_CP045298.1\|WP_152381664.1\|5014709_5016641_+\|fructose-bisphosphatase-class-III	unknown	unknown	gnl\|CDD\|377726
NZ_CP045298.1\|WP_152381670.1\|5022361_5023348_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|378925
NZ_CP045298.1\|WP_025718058.1\|5021588_5022365_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|366444
NZ_CP045298.1\|WP_152381668.1\|5020050_5020308_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045298.1\|WP_152381678.1\|5036827_5037754_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP045298.1\|WP_167518760.1\|5031807_5032701_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|366234
NZ_CP045298.1\|WP_152381671.1\|5023415_5026034_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|225461
NZ_CP045298.1\|WP_152381669.1\|5020628_5021576_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP045298.1\|WP_167518758.1\|5018462_5018774_+\|winged-helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379282
NZ_CP045298.1\|WP_152381677.1\|5033151_5033877_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853

Protein	Function_ID	Function_description	E-value
NZ_CP045298.1\|WP_152381674.1\|5031445_5031778_+\|transposase	gnl\|CDD\|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.03315e-07
NZ_CP045298.1\|WP_152381679.1\|5037818_5039120_+\|VWA-domain-containing-protein	gnl\|CDD\|225281	COG2425, COG2425, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain [General function prediction only].	6.67467e-47
NZ_CP045298.1\|WP_152381672.1\|5029242_5030006_-\|IS5-family-transposase	gnl\|CDD\|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	5.72923e-31
NZ_CP045298.1\|WP_167518757.1\|5018251_5018428_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|379402	pfam13936, HTH_38, Helix-turn-helix domain. This helix-turn-helix domain is often found in transferases and is likely to be DNA-binding.	0.00608629
NZ_CP045298.1\|WP_152381676.1\|5032861_5033146_+\|transposase	gnl\|CDD\|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	1.34699e-11
NZ_CP045298.1\|WP_152381666.1\|5019125_5019530_+\|hypothetical-protein	gnl\|CDD\|274791	TIGR03799, NOD_PanD_pyr, putative pyridoxal-dependent aspartate 1-decarboxylase. This enzyme is proposed here to be a form of aspartate 1-decarboxylase, pyridoxal-dependent, that represents a non-orthologous displacement to the more widely distributed pyruvoyl-dependent form (TIGR00223). Aspartate 1-decarboxylase makes beta-alanine, used usually in pathothenate biosynthesis, by decarboxylation from asparatate. A number of species with the PanB and PanC enzymes, however, lack PanD. This protein family occurs in a number of Proteobacteria that lack PanD. This enzyme family appears to be a pyridoxal-dependent enzyme (see pfam00282). The family was identified by Partial Phylogenetic Profiling; members in Geobacter sulfurreducens, G. metallireducens, and Pseudoalteromonas atlantica are clustered with the genes for PanB and PanC. We suggest the gene symbol panP (panthothenate biosynthesis enzyme, Pyridoxal-dependent). [Biosynthesis of cofactors, prosthetic groups, and carriers, Pantothenate and coenzyme A].	3.72269e-28
NZ_CP045298.1\|WP_152380558.1\|5036525_5036837_+\|transposase	gnl\|CDD\|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	5.9127e-08
NZ_CP045298.1\|WP_152381664.1\|5014709_5016641_+\|fructose-bisphosphatase-class-III	gnl\|CDD\|377726	pfam06874, FBPase_2, Firmicute fructose-1,6-bisphosphatase. This family consists of several bacterial fructose-1,6-bisphosphatase proteins (EC:3.1.3.11) which seem to be specific to phylum Firmicutes. Fructose-1,6-bisphosphatase (FBPase) is a well known enzyme involved in gluconeogenesis. This family does not seem to be structurally related to pfam00316.	0
NZ_CP045298.1\|WP_152381670.1\|5022361_5023348_+\|ABC-transporter-permease	gnl\|CDD\|378925	pfam12698, ABC2_membrane_3, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family pfam01061.	2.0221e-09
NZ_CP045298.1\|WP_025718058.1\|5021588_5022365_+\|ABC-transporter-permease	gnl\|CDD\|366444	pfam01061, ABC2_membrane, ABC-2 type transporter.	6.48308e-12
NZ_CP045298.1\|WP_152382248.1\|5034982_5035693_+\|alpha/beta-hydrolase	gnl\|CDD\|378924	pfam12697, Abhydrolase_6, Alpha/beta hydrolase family. This family contains alpha/beta hydrolase enzymes of diverse specificity.	5.85074e-05
NZ_CP045298.1\|WP_152381678.1\|5036827_5037754_+\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	1.38783e-26
NZ_CP045298.1\|WP_167518760.1\|5031807_5032701_+\|IS3-family-transposase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	2.65143e-20
NZ_CP045298.1\|WP_152381671.1\|5023415_5026034_+\|AAA-family-ATPase	gnl\|CDD\|225461	COG2909, MalT, ATP-dependent transcriptional regulator [Transcription].	3.13635e-112
NZ_CP045298.1\|WP_152381669.1\|5020628_5021576_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.56866e-98
NZ_CP045298.1\|WP_167518758.1\|5018462_5018774_+\|winged-helix-turn-helix-domain-containing-protein	gnl\|CDD\|379282	pfam13592, HTH_33, Winged helix-turn helix. This helix-turn-helix domain is often found in transferases and is likely to be DNA-binding.	4.40847e-19
NZ_CP045298.1\|WP_152381677.1\|5033151_5033877_+\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	5.0283e-33

>NZ_CP045298.1|WP_152381671.1|5023415_5026034_+|AAA-family-ATPase
MGSFQLLSAKLKAPALRKQYVPRPELYRKLDRLSDHKVLVVQGSAGSGKTTLMTSYMSERPDLGWYWITLDEANNDARSFWYYVLEALKGLFGQEPEHLRTMFDALSQKPNLDHLLVLLVNRLEECRAVGTLVLDDFHFIDDTTLLQSLTFFLRFSPETIRIVLLTRETPKLYLGELAMSGQYLEVNERELAFTHEEANLFLTQTLGLTLEPSTVHKLYQWAEGWVGGLQLSALAVVHHTHTLTEPVGTLNRYMVDYLSNEILRSVSDWEQQFMLQTSVLAYFNEKICNWMLDINDAAVIITKLVEKHLFVITVDEEEGLYRYHQVFGDFLRAKLREQGEDTVRSLHLRAAEVYERMGSSEESLQHYLWAEAYEEAIRLLLATGHHFPNWSYLRQIPLDILSSSRPLMFQRLFYHFCNLEIEDMRQIINLTPQQEEDGLGSLFQLCRFMLGDEVFDLPVGMEWLENWESFEMDAVTRAIILVTGGTMLSLKDQFATAMNWLNQAKRLEKLSPNPFLRFSILSSQAQVLETLGEFSACLSLYEIMFDLCENYPMLHPMKVINWIGLTGIQLKMMKLELAEESIATAKQIFFDDDSQLKSAYLYNEMELRVLHGDNTRAIELLEELKKFPLYQSPTYFTSILKYMLRYGLSNIEMENELLNRVEEPHSKAFIRLEDRLACARIRVARGEKELAYQHLDVLLPHARKHGIRTILVEGLLLKMTLIASASSVPGKELFQVLREAVHYGYENEYLSPFCLEMERLRPYFGLFLKDPDQELNSKEKCFAQLIQTLLEQSKMQVSLPVSPKEREKAILSERELEVLQVLATGCSNKEIGVMLCISLATVKSHVINIYAKLQVSNRVEAVERGRELGLLY
>NZ_CP045298.1|WP_152381670.1|5022361_5023348_+|ABC-transporter-permease
MKATFRIFCNHSLRMWNRRNVIVITLIMTLASMALAIYFTAQSELKGTLAVVTSQKVSLTLSSEQYRIQYLQQPPPKSELVKNRYDAVVTFNSDGSHRIESLKSDEFKQQLEQAIVHPHAPLPVMPQRGIGTNILGYLTMFLLIQALFYLQLFSDDKKTGTFRRTAVSPAGIVPYLSAQCLFGFMAVYVPTWLVLALAKAVGINIGFGLGTYSLLLVLPALLAVSFALFMAAWIENSDNGLSLSSAIILLSSVLSGSFYTIAHENGIMKVITSVFPQQHFITLVQEMELKGAVGLYWEHALYVIVASAVLAAAGWLICKNRFRKGFYG
>NZ_CP045298.1|WP_025718058.1|5021588_5022365_+|ABC-transporter-permease
MTDSRKKTGLLFPFSIILKRDFINLATNVSLILSNTIFPLLLIFVLGYLGGGLYGGSDVTSYDYYGVTILIYSALNVSMTAANSFMDQNVKRSNLRILYAPIPKSFIYLSKTAATFLFTGLCSIVLVALLQLVFNIRLGGTSAVYTAVVLLCFDLFSSALGVLFCCLFKGEELTNKILSIINSVLAILGGLFFQLDGLGRTAEVISFFSPVKWVVETVLRIVYDGDFSLFLPTLLSFVIASLLLLWGCKRTFKTEDYI
>NZ_CP045298.1|WP_152381669.1|5020628_5021576_+|ATP-binding-cassette-domain-containing-protein
MISNSPIIEVSELSKSFGSRTSLNNVTFDVHQGEILCFLGPNGAGKTTTINILSTSLRGDQGNIRYCGEPVERLMSQYKRELGIVPQDLAVYEDISAEANVRFFASLYGMTGTELEQGTNEALEIVGLTDRRKDKPKTFSGGMKRRLNMACAIAHRPKMIIMDEPTVGIDPQSRNHILGSIRKLRDEGATIIYTTHYMEEVEEISTRILIIDHGEVIASGTKEELKERLADEKRYEVEVEEINEMPDIDLYRIDGVKKVDIVGNRIHISTLKGIENLDQIIVNITSNGLKIINLTGFSPSLEMVFLNLTGRTLRD
>NZ_CP045298.1|WP_152381668.1|5020050_5020308_+|hypothetical-protein
MNELRGDADIRLTAGSATLGWTELTGRERINVHCGTGGIDILLPAIETTVLDQGFLPRAKRITTHTGSEISGVIGIGTFDIKHWQ
>NZ_CP045298.1|WP_167518759.1|5019586_5019841_+|hypothetical-protein
MKHMVLRMPKSLQTFPKGAIKNAQIHQRFPAIGITEFRIDVHTLENMLICFDAEKEISFVASGEKHLLLNEFALAAHSCSREVT
>NZ_CP045298.1|WP_152381666.1|5019125_5019530_+|hypothetical-protein
MLDEGIRKNHWMVKLLASHPAFELIGEPEINILTYRYIPASLREAVRSCTLRPEEHDRINHFNELLQEMQSQQGDSFVSRTTLCGIEGMPNSVVVLRVILANPLTTKAHIQSVLKIQQEIARDLELSFEYNTDS
>NZ_CP045298.1|WP_167518758.1|5018462_5018774_+|winged-helix-turn-helix-domain-containing-protein
MLEQQQPADVGFDARYTWTLPLVAEWIKREFGITMSVRGISAMLKRMNFSFTKATYTLAKADEEAQALIIPGVPIHPEQYISHLIREVVHHCINTSSPNLSAI
>NZ_CP045298.1|WP_167518757.1|5018251_5018428_+|helix-turn-helix-domain-containing-protein
MKNEEIERLHTAMKETTDKRLYERYLAVRLRLEGHSFAEIGDLLGRIRQTISIYWQSY
>NZ_CP045298.1|WP_152381664.1|5014709_5016641_+|fructose-bisphosphatase-class-III
MDEQFLDLLAEKYDTEEKVITEIINLEAISNLPKGTEHYVSDLHGEFHAFQHVLRNGSGNVKEKIKDLFREVWTDNEINDFAALVYYPEEKIQLVKADLCNKQALNRWHRQTIEQMLKLISYASSKYTRSKLRKALPEQFVYIVEELLYKTDLTNNKDSYYEEIYQQIISLGQADKLIIGLAYTTQSLVVDHLHVVGDIYDRGPDPDKIMDTLINYHSVDIQWGNHDVLWIGAYAGSLVCLANIIRICARYDNLDIVEDVYGINLRPLLNLAEKYYDDNPAFRPKLQVDHNASEQEILQITKIHQAIALIQFKLEIPIIKRRPYFNMSERLLLEQIDYDKNEIKIGGKTYPLENTCFATVNPQQPGQLLEEEQQVMEKLLFSVQHSEKLARHMNFLMKKGSLYLKYNGNLLIHGCIPLDEEGNMQEMQINDKTYSGRQLLDVFEDYLRYAFAHPEETDDLATDMVWYIWTGECSSLFGKREMTTFERYFIQDKETHKERKNPYYHLRENEEICRKILLEFDLNPDHGHVINGHTPVKEIRGENPVKANGKMVVIDGGFSKAYQSTTGIAGYTLLYNSFGMQLVAHKKFNSKEDVLCNGTDVLSVKRLVDKELERKLVRETNVGEKLLQKISNLKNLLEYRYMK
>NZ_CP045298.1|WP_152381672.1|5029242_5030006_-|IS5-family-transposase
MRRRYELTDEEWNILEPLLPPARKKQGGRPPKDRRQMLNAVLWVARTGAPWRDLPSTYGPWSSAYSFFWRLQKANIWNEILKHVAIEPDWEQVMIDATIVRVHQHGAGAKGGKDRQAIGRSRGGLTTKIHAMVDALGYPLRFELTPGQDHDSVTGYRLLHGLDVCPGEVLADRAYDTNAILELLQSRSITPVIPCKRNRRVKRPLDSETYKERHLVECFFNKVKNYRRLATRYEKTANMFMAFLTLLSIRLWLK
>NZ_CP045298.1|WP_152381673.1|5030794_5031070_+|hypothetical-protein
MAICLNYELVKIRGTVAEYRFGNCLSDLDGIFEIDLPKLIGGEISMEAPINEVVRLKNNSQSQAMVNRVFGKIYKHYLENNEYPSKDGYYA
>NZ_CP045298.1|WP_152381674.1|5031445_5031778_+|transposase
MQRRRFTMEFKQQVIQEAREVGNASQVARRHNINPKMLYRWMDQAEHTDWKTTDISAKAISAYAPSPQEFRALEGENKQLKEILGEKDLEIAVLRDLLKKQNPAYRTKLK
>NZ_CP045298.1|WP_167518760.1|5031807_5032701_+|IS3-family-transposase
MSRILRIVGVSEQIYYYRKKQPSNQTSVKHKGGRPVPGFSMTKTGVPMSDGQIQEWLCELLNDETEVYGYRKLTICLQREHHLVINKKKVYRLLAKMKMLQPQRRKRLKHPRKLANNREIKTSNELWEMDIKYGYIAGEQRFFYLLCVIDVLDREVIDFYMGLSCEGKHAAGLIQRTLWQRQLFETEQRPVIRTDNGPQFISHVFEEACVTHDVTHERIPPKTPNKNAHIEPFHSLLEAECLQRYEFSSYREAYETVTSYIRFYNERRMHGSLYDLAPKQFRQAIAMQQVQAKTVKV
>NZ_CP045298.1|WP_152381676.1|5032861_5033146_+|transposase
MTKKERRTFSAEFKAQMVQLYQSGKPRKDIIQEYDLNPSSLDKWVKQSATSGSFKEKDNRTPEELELIELRKQNKQLLMENDILKQAALIMGRK
>NZ_CP045298.1|WP_152381677.1|5033151_5033877_+|IS3-family-transposase
MRQNKHKYSVSAMCDVLKIPRSTYYYEEGKDEATSEDETSSIVIDIFQTSRQNYGTRKIKKALHQQGFTVSRRRIGRIMKEYGMVSSYTVAQYKPHSTRCNEAKQANVLDRKFEQEQELSVVVSDLTYVRVGSYGNYVCLFVDLFNREIISYSAGPHKDAKLVYRALASIKGNLNDIQLFHTDRGNEFKNKLIDDALEAFQIERSLSMKGCLYDNAVAEATFKIFKTEFVKKRHFESLADY
>NZ_CP045298.1|WP_152382248.1|5034982_5035693_+|alpha/beta-hydrolase
MIKQELKIEGIPAILWGGKSDKIFIAIHGNMSNKADDVIVIFAEEATVQGYQVISFDLPEHGDRKEEAYACKVQNCVHDLDIIMRYTQKQSDDISIFACSMGAYFSLLAYNNFPLKQCLFLSPVLDMERIIKNMMTWFSVSEDRLKVEREISTPIGQTLYWDYYCYVKSHPVDTWNKPTAILYGSEDDLCEYDVISTFASRFHCHLKVMKHGKHYFHTKEQLQFYRQWLKEHLFAN
>NZ_CP045298.1|WP_152380558.1|5036525_5036837_+|transposase
MTRNKHSREFKCQIVKEAIETGNKAAVARRYEIAVNMLHRWVKEFEEGKYGETSLETIHGLDSKVLSQENDQLKKLLGEQALEIAILRDLIKKKNPHLLKKWK
>NZ_CP045298.1|WP_152381678.1|5036827_5037754_+|IS3-family-transposase
MEVAEHYICEGYAVTLVLRLANIPRSSYYYHKNRKLIEKTASGGRQKPGYSLRSDGVKVPDAQIMERIMELISADGHAYGYRKLTVALRRDDGLIINKKKVYRLCRELSILRPQRKVNSSYPRKLVRNRMITNSNQRFETDIKYGYIAGEDRFFFIQSCLDVYDRSVVAYHIGLRCEAKDVIRTLQMALFKRQLFEVQTKPVIRSDNGPQFISHGFEAACKSFGVEHERIPPRTPNMNAHIESFHRLLQDECLARYDFETYSEAYEAVTEFIHFYNERRIHSSICDLSPSQFYEKNKTKPIPIREVRV
>NZ_CP045298.1|WP_152381679.1|5037818_5039120_+|VWA-domain-containing-protein
MEMSDKLKEVEEEGNKLFPSFQPLMGDLWAGLFKMKPELLEDVGEKLTMNRQLMEKVMADDGYTDFREFTCLDDLAAALGTTKYSETVLGWVKEQTKQDQDLAEALQQLMDGEQGASQQAADALSTALSQNGKSLSRMLSRAAQEAVEAKENVKSLLGGIQAGSGDGEMKKVPLKDQLFLAEKLSTDRRLREIAAWAGRMKVIANRKQRSKHKDAISRNGIRQGNDIEQLLPMELGSYASPISKMDFLRRYAEGQTLQYDTNGNEQLGKGPIILCLDQSGSMRDQDTISKGFALALMSIARKQRRDFAWIPFSSHASDPLIYERGKISVKNMIQLATVFLDGGTKFVAPLTKAAEVIKQSRFHQADIIFVTDGEAHVNDQFIDYWNELKKEKGFSVLSMLLGTESIQGVQGFSDRIVKASSFEDESVYQAFEI

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Crispr_ID: NZ_CP045298_13

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045298_13

5068039-5068112

Orphan

Consensus_repeat	Method
AATTCTTCCGCTGCTAACGAGCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045298_13

>merge|NZ_CP045298|13|5068039-5068112|CRISPRCasFinder
AATTCTTCCGCTGCTAACGAGCCATCTAAGGAGTTAACCGGCGAGGGTGCCAATTCTTCCGCTGCTAACGAGCC

>NZ_CP045298|13|13|5068039-5068112|CRISPRCasFinder
AATTCTTCCGCTGCTAACGAGCC	ATCTAAGGAGTTAACCGGCGAGGGTGCC
AATTCTTCCGCTGCTAACGAGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045298.1\|WP_152381701.1\|5061343_5061505_-\|MerR-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133382
NZ_CP045298.1\|WP_152381708.1\|5068927_5069671_+\|twin-arginine-translocase-subunit-TatC	unknown	unknown	gnl\|CDD\|376413
NZ_CP045298.1\|WP_152381711.1\|5073354_5074365_+\|hydrogenase-expression/formation-protein-HypE	unknown	unknown	gnl\|CDD\|100033
NZ_CP045298.1\|WP_152381705.1\|5067205_5067868_+\|hydrogenase-nickel-incorporation-protein-HypB	unknown	unknown	gnl\|CDD\|349775
NZ_CP045298.1\|WP_152381710.1\|5072037_5072262_+\|HypC/HybG/HupF-family-hydrogenase-formation-chaperone	unknown	unknown	gnl\|CDD\|376549
NZ_CP045298.1\|WP_167518763.1\|5059614_5060937_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379756
NZ_CP045298.1\|WP_152381699.1\|5058441_5059062_-\|phosphatase-PAP2-family-protein	unknown	unknown	gnl\|CDD\|239480
NZ_CP045298.1\|WP_152381712.1\|5074493_5075498_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225911
NZ_CP045298.1\|WP_152381703.1\|5066394_5066871_+\|hydrogenase-maturation-protease	unknown	unknown	gnl\|CDD\|99873
NZ_CP045298.1\|WP_152382252.1\|5072257_5073340_+\|hydrogenase-formation-protein-HypD	unknown	unknown	gnl\|CDD\|376666
NZ_CP045298.1\|WP_152381713.1\|5076129_5076303_+\|recombinase-family-protein	unknown	unknown	gnl\|CDD\|239737
NZ_CP045298.1\|WP_152381697.1\|5056324_5056858_-\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|224511
NZ_CP045298.1\|WP_167518764.1\|5076778_5077336_-\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|235339
NZ_CP045298.1\|WP_152381698.1\|5056902_5058168_-\|phosphatase-PAP2-family-protein	unknown	unknown	gnl\|CDD\|223659
NZ_CP045298.1\|WP_152381674.1\|5077365_5077698_-\|transposase	unknown	unknown	gnl\|CDD\|225511
NZ_CP045298.1\|WP_152382251.1\|5064973_5066392_+\|Ni,Fe-hydrogenase-I-large-subunit	unknown	unknown	gnl\|CDD\|380187
NZ_CP045298.1\|WP_152381704.1\|5066863_5067205_+\|hydrogenase-maturation-nickel-metallochaperone-HypA	unknown	unknown	gnl\|CDD\|376468
NZ_CP045298.1\|WP_152381702.1\|5064058_5064946_+\|hydrogenase-small-subunit	unknown	unknown	gnl\|CDD\|224654
NZ_CP045298.1\|WP_152381709.1\|5069701_5072065_+\|carbamoyltransferase-HypF	unknown	unknown	gnl\|CDD\|223146
NZ_CP045298.1\|WP_152381707.1\|5068185_5068935_+\|Sec-independent-protein-secretion-pathway-component-TatC	unknown	unknown	gnl\|CDD\|376413

Protein	Function_ID	Function_description	E-value
NZ_CP045298.1\|WP_152381701.1\|5061343_5061505_-\|MerR-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|133382	cd01107, HTH_BmrR, Helix-Turn-Helix DNA binding domain of the BmrR transcription regulator. Helix-turn-helix (HTH) multidrug-efflux transporter transcription regulator, BmrR and YdfL of Bacillus subtilis, and related proteins; N-terminal domain. Bmr is a membrane protein which causes the efflux of a variety of toxic substances and antibiotics. BmrR is comprised of two distinct domains that harbor a regulatory (effector-binding) site and an active (DNA-binding) site. The conserved N-terminal domain contains a winged HTH motif that mediates DNA binding, while the C-terminal domain binds coactivating, toxic compounds. BmrR shares the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements.	7.585e-16
NZ_CP045298.1\|WP_152381708.1\|5068927_5069671_+\|twin-arginine-translocase-subunit-TatC	gnl\|CDD\|376413	pfam00902, TatC, Sec-independent protein translocase protein (TatC). The bacterial Tat system has a remarkable ability to transport folded proteins even enzyme complexes across the cytoplasmic membrane. It is structurally and mechanistically similar to the Delta pH-driven thylakoidal protein import pathway. A functional Tat system or Delta pH-dependent pathway requires three integral membrane proteins: TatA/Tha4, TatB/Hcf106 and TatC/cpTatC. The TatC protein is essential for the function of both pathways. It might be involved in twin-arginine signal peptide recognition, protein translocation and proton translocation. Sequence analysis predicts that TatC contains six transmembrane helices (TMHs), and experimental data confirmed that N- and C-termini of TatC or cpTatC are exposed to the cytoplasmic or stromal face of the membrane. The cytoplasmic N-terminus and the first cytoplasmic loop region of the Escherichia coli TatC protein are essential for protein export. At least two TatC molecules co-exist within each Tat translocon.	5.94953e-44
NZ_CP045298.1\|WP_152381711.1\|5073354_5074365_+\|hydrogenase-expression/formation-protein-HypE	gnl\|CDD\|100033	cd02197, HypE, HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis. HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the ATP-binding domains of the AIR synthases, selenophosphate synthetase (SelD), and FGAM synthase and is thought to bind ATP.	1.57444e-164
NZ_CP045298.1\|WP_152381705.1\|5067205_5067868_+\|hydrogenase-nickel-incorporation-protein-HypB	gnl\|CDD\|349775	cd05390, HypB, nickel incorporation protein HypB. HypB is one of numerous accessory proteins required for the maturation of nickel-dependent hydrogenases, like carbon monoxide dehydrogenase or urease. HypB is a GTP-binding protein and has GTP hyrolase activity. It forms homodimer and is capable of binding two nickel ions and two zinc ions. The active site is located on the dimer interface. Energy from hydrolysis of GTP is used to insert nickels into hydrogenases.	2.67037e-105
NZ_CP045298.1\|WP_152381710.1\|5072037_5072262_+\|HypC/HybG/HupF-family-hydrogenase-formation-chaperone	gnl\|CDD\|376549	pfam01455, HupF_HypC, HupF/HypC family.	1.73062e-26
NZ_CP045298.1\|WP_167518763.1\|5059614_5060937_+\|hypothetical-protein	gnl\|CDD\|379756	pfam15978, TnsD, Tn7-like transposition protein D. TnsD is a family of putative Tn7-like transposition proteins type D.	2.69922e-66
NZ_CP045298.1\|WP_152381699.1\|5058441_5059062_-\|phosphatase-PAP2-family-protein	gnl\|CDD\|239480	cd03385, PAP2_BcrC_like, PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from Bacillus subtilis posesses undecaprenyl pyrophosphate (UPP) phospatase activity, and it is hypothesized that it competes with bacitracin for UPP, increasing the cell's resistance to bacitracin.	1.16666e-42
NZ_CP045298.1\|WP_152381712.1\|5074493_5075498_+\|hypothetical-protein	gnl\|CDD\|225911	COG3376, HoxN, High-affinity nickel permease [Inorganic ion transport and metabolism].	2.71869e-105
NZ_CP045298.1\|WP_152381703.1\|5066394_5066871_+\|hydrogenase-maturation-protease	gnl\|CDD\|99873	cd06062, H2MP_MemB-H2up, Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD from E. coli is well studied in this group. Maturation of [NiFe] hydrogenases include proteolytic processing of large subunit, assembly with other subunits, and formation of the nickel metallocenter. Hydrogenase maturation endopeptidase (HybD) cleaves a short C-terminal peptide after a His or an Arg residue in the large subunit (pre-HybC) of hydrogenase 2 (hyb operon) in E. coli. This cleavage is nickel dependent. A variety of endopeptidases belong to this group that are similar in function and sequence homology. They include such proteins as HynC, HoxM, and HupD.	1.4395e-45
NZ_CP045298.1\|WP_152382252.1\|5072257_5073340_+\|hydrogenase-formation-protein-HypD	gnl\|CDD\|376666	pfam01924, HypD, Hydrogenase formation hypA family. HypD is involved in hydrogenase formation. It contains many possible metal binding residues, which may bind to nickel. Transposon Tn5 insertions into hypD resulted in R. leguminosarum mutants that lacked any hydrogenase activity in symbiosis with peas.	0
NZ_CP045298.1\|WP_152381713.1\|5076129_5076303_+\|recombinase-family-protein	gnl\|CDD\|239737	cd03768, SR_ResInv, Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1.	7.76749e-13
NZ_CP045298.1\|WP_152381697.1\|5056324_5056858_-\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|224511	COG1595, RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription].	8.55892e-43
NZ_CP045298.1\|WP_167518764.1\|5076778_5077336_-\|tyrosine-type-recombinase/integrase	gnl\|CDD\|235339	PRK05084, xerS, site-specific tyrosine recombinase XerS; Reviewed.	6.20881e-58
NZ_CP045298.1\|WP_152381698.1\|5056902_5058168_-\|phosphatase-PAP2-family-protein	gnl\|CDD\|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	2.70999e-34
NZ_CP045298.1\|WP_152381674.1\|5077365_5077698_-\|transposase	gnl\|CDD\|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.03315e-07
NZ_CP045298.1\|WP_152382251.1\|5064973_5066392_+\|Ni,Fe-hydrogenase-I-large-subunit	gnl\|CDD\|380187	NF033181, NiFeSe_hydrog, nickel-dependent hydrogenase large subunit. Members of this family are the large subunit of the periplasmic nickel-dependent hydrogenase. Some members contain a selenocysteine residue.	0
NZ_CP045298.1\|WP_152381704.1\|5066863_5067205_+\|hydrogenase-maturation-nickel-metallochaperone-HypA	gnl\|CDD\|376468	pfam01155, HypA, Hydrogenase/urease nickel incorporation, metallochaperone, hypA. HypA is a metallochaperone that binds nickel to bring it safely to its target. The targets for Hypa are the nickel-containing enzymes [Ni,Fe]-hydrogenase and urease. The nickel coordinates with four nitrogens within the protein. The four conserved cysteines towards the C-terminus bind one zinc moiety probably to stabilize the protein fold.	3.6472e-39
NZ_CP045298.1\|WP_152381702.1\|5064058_5064946_+\|hydrogenase-small-subunit	gnl\|CDD\|224654	COG1740, HyaA, Ni,Fe-hydrogenase I small subunit [Energy production and conversion].	8.12501e-86
NZ_CP045298.1\|WP_152381709.1\|5069701_5072065_+\|carbamoyltransferase-HypF	gnl\|CDD\|223146	COG0068, HypF, Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones].	0
NZ_CP045298.1\|WP_152381707.1\|5068185_5068935_+\|Sec-independent-protein-secretion-pathway-component-TatC	gnl\|CDD\|376413	pfam00902, TatC, Sec-independent protein translocase protein (TatC). The bacterial Tat system has a remarkable ability to transport folded proteins even enzyme complexes across the cytoplasmic membrane. It is structurally and mechanistically similar to the Delta pH-driven thylakoidal protein import pathway. A functional Tat system or Delta pH-dependent pathway requires three integral membrane proteins: TatA/Tha4, TatB/Hcf106 and TatC/cpTatC. The TatC protein is essential for the function of both pathways. It might be involved in twin-arginine signal peptide recognition, protein translocation and proton translocation. Sequence analysis predicts that TatC contains six transmembrane helices (TMHs), and experimental data confirmed that N- and C-termini of TatC or cpTatC are exposed to the cytoplasmic or stromal face of the membrane. The cytoplasmic N-terminus and the first cytoplasmic loop region of the Escherichia coli TatC protein are essential for protein export. At least two TatC molecules co-exist within each Tat translocon.	8.72476e-39

>NZ_CP045298.1|WP_152381705.1|5067205_5067868_+|hydrogenase-nickel-incorporation-protein-HypB
MSSIKVVTSILKVNDELTQQNKKLMNEKGLYVINLMSSPGSGKTSILEKVIAKLKDEVKIAVIEGDLYTTKDAERIEAHGVQVVQINTEGGCHLDGQMIRNALTHLNLDETNLLIIENVGNLICPASFELGEDLIITVLSTTEGNDKPQKYPRMFEKSGIVILNKIDLVPHTNFDKDEFHKDIREINPKAKVIETSCMTGQGIDELCAWLKKTISISNPV
>NZ_CP045298.1|WP_152381704.1|5066863_5067205_+|hydrogenase-maturation-nickel-metallochaperone-HypA
MHEAAIVESALELILVKAEEHHLTKIRRITAKVGELSGALPEAMQFVFQNASQGTIAEGSDFIIEHVEATASCGSCDITFPIRYYHPVCPSCGGLDNQVLTGYELYIDTMEGD
>NZ_CP045298.1|WP_152381703.1|5066394_5066871_+|hydrogenase-maturation-protease
MKDTVVIGIGNILLKDDGIGVHTIRELENEDLPSTVELVDGGTSTLAMLSYFLESRRIIVIDALKAGLDPGTIYRISPEDIAGYEKGNLSIHDTQILDVVQMARMLGAAPNVIIFGIEPQEIGFELEMSDLMRSKIPEIIGLIKQELGFASQEEKNFA
>NZ_CP045298.1|WP_152382251.1|5064973_5066392_+|Ni,Fe-hydrogenase-I-large-subunit
MSTIKLDPVTRLEGHLKVEVTLDANNKVVSAAVAGMLFRDFENMLLNRPPRDAAFLTQRICGVCPVPQAVASVKAVEKIKGFKPNLQGLMLRNLIQGANFLDSGITHFYHLSLLDYIQGPQISPWVGGYTQDLRFSAADTQTLTDHYISALQIRRKANEMAAIFSGKLPHAANIVPGGVTALPSATEINNFRNYLNDIQSFISSTYQADVNMLASAYSDYYSMGTGYGNLITFGAFDTNTSGGLLFPAGTVTGGTVGAFNETNIKEFNKYSYYSSPSGQAPASGTTTASYGKSGAYTWLKSPRYNNTPFEAGPLARAWVSGDYRRGVSVMDRHMARYVEMAKLVSNMQTWLDQLTPGASGFTNIGDPVSGSASGLTEAPRGAIGHWLSVSSSQISKYQIITPTCWNASPMDDSGNPGPVEKALIGTQLADPAQPVELLRIVHSFDPCTGCSVHVMSPEGGEMSKFIVQPLGK
>NZ_CP045298.1|WP_152381702.1|5064058_5064946_+|hydrogenase-small-subunit
MRINRRDFLKWSAAAVAALKLEMDMDKLNMVMAAETDPPVIWLLGSGCSGCSISTLNVTNPTTIEDVLQNKISMKYDSTIMAASGESAMQALENAANQYNGQFILVIEGAIPGGASKNYCIIGEQNGVPLTMYDAVLKYGPKAKYVVASGTCASFGGVAAAAPNSTGCVSVKSLLSGKTPNPVVNLAGCPVNATVMVQTLLDLILTGLPSLDSNSRPSKFFGTTIHSVCPRKGQTQVSQPGIYGCYKNIGCKGPGNQSPCPSLMWNNKQGWCIQSDYPCIGCTAPVFPLNPIITV
>NZ_CP045298.1|WP_152381701.1|5061343_5061505_-|MerR-family-DNA-binding-transcriptional-regulator
MLKISVFSKLSRVSVKTLRFYDELGLLKPATVDKKHSANLNTTCCSVLFLPNV
>NZ_CP045298.1|WP_167518763.1|5059614_5060937_+|hypothetical-protein
MSGYLSRCTRDVGFHVWCELIHFHTLYLYYKPFCSIQQCRQVKEEMAADKSQRIQMIAGVMASIIRIHKVLKICPLCLQADLDQFGEAYWHRTHQLPGVLVCPIHNCLLLEKCHQCNEDFMDQRIQYPALPTAFCRNHHALSEMVRIVEDLRLIGLSDFSNYILKGGYSEYNKEQMYDKYIQRLIRLGYCTATGRVKQREVREFFLSQYNPQFLTQIAVKLPEDNDFNWLSTILRKSRRSQHPLLHILIIQLLWDSPESIKLEGASSPFGFGPWPCLNPISDHHHVNVIPHVKIKRCSNTRRPVGTFECPSCGFTYSRRGPDQDRSAIYTIGRIKKFGPIWISQLEQLSKDHALGLRELSRLMKCDPKTIKRYLIGSISLKNEVNNLTNFQQRKKKRKATPTTKKSNVTPVRVDWAIRDQEINMLIKDAIKKLNNKRVSL
>NZ_CP045298.1|WP_152381699.1|5058441_5059062_-|phosphatase-PAP2-family-protein
MNKEKSAMDYTLFQMINRLAGIYTFLNPLMKFLAEDAQYLFYGGVIIYWFTRTNRNRRMVIEAFASACLALGFGGILALLFYRDRPFVAHHVIQLINHPANASFPSDHATGAFVIAAAIWMFRKKDGLVWLILAASISISRIWTGVHYPSDVVTGAIIGMVSAIFVHRLFTRWYFADKCMSYGLEMYEKIEQKIWAKMQSPQGKTR
>NZ_CP045298.1|WP_152381698.1|5056902_5058168_-|phosphatase-PAP2-family-protein
MDQHGYLVLGIALTLELLALPLPGEVLMTYTGLLVFQGHLNWMVSILTAGLGTSMGMTISYWIGYKLGKPFFQKHGSKFHLGPEKLEKTSLWFERYGNKLLLFAYFIPGVRHLTGYFSGITRLPFRTYMIFAYTGAFLWTSMFISLGKILGPKWELFHHTITKYLIIAGLIAAVVFACVYVYKKYRDQIYDATLAGLRKGVKIFHTLGRVRFLLLTSFGVFLILFMVMASLIQDLLANEFADFDVVTSYIVHALFDESWAFWMNLFAYLASFQVLFTVAVLALIMILIKGEDRLLEWTFLLFVFVGGELWDEGLRRLFHRIGPSSLINTFPSEQTLITVIFLGFAAYLIVRHVKMAGVQTGASLLVLTVAFLVGISRIYFNIQYPSDVVAGYVFGGVWLSLNVVLLEVLRLMKHNKLNFST
>NZ_CP045298.1|WP_152381697.1|5056324_5056858_-|sigma-70-family-RNA-polymerase-sigma-factor
MDQELFRLIGKAKSGETEAFALLVKQYKDRVFRFAFGMLSDRMEAEDVSQEAFIKAYYSLSNLENSYAFSSWLTRIVSNLCYDRIQKRKKENIVSSDQIEAGISTQGIERRDLHLTIEEAMKTLSPEHREAILLRDVEGYTYDEIAGMLHIPLGTVKSRINAARVQLRKELKKGVEE
>NZ_CP045298.1|WP_152381707.1|5068185_5068935_+|Sec-independent-protein-secretion-pathway-component-TatC
MWESENIVSAVRWLGKFRARILAGVLVVIAAATAVYAVSDPLLKLLCRPLQDQPLFFMTPVDGVMTKLWVAMFGGVLASFPVLACLLVSMFASLLDRSIRLKIYFLTIPLAVVLFAGGIAFAYEFILPNTVDFLIQSGEGVLKPMISGSAYVSFIAFFLISVALVFELPIVMVALSRIGLIHSKMLMRKRKFAVLGIVIILALLSPTPDAFSLLAESIPVVALYEISIWTIYLLERKGMSRMKRVTTDD
>NZ_CP045298.1|WP_152381708.1|5068927_5069671_+|twin-arginine-translocase-subunit-TatC
MINQNRLQQDTDRPVVEHLAELRRRLIVTVASVIVLTAVIYSKAFLIVEVLKRSVGNEWLDLAFFSLTGAFVLRVKLSFIASLIALSPLIGYQLFAFIGPGLTAKERKVLLSAVFYMVPCFVLGVVLSYVVVVPSVLHALLTYGNSYMKAALSGEEYISFIAMLCVVFGLVFTLPFPLIALGKLGLLRSSWMKKVRVSIVLSVLIGEGLFAADITSVILLAIPLILIYEISLRVVIRMEKRREAASL
>NZ_CP045298.1|WP_152381709.1|5069701_5072065_+|carbamoyltransferase-HypF
MLSEVIRVDVQVKGIVQGVGFRPFVYRLAHQHDLKGWVTNDASGVRLEAEGRSPDIDAFLLSLRASPPPLSHIEELTAEVHSPIGYAEFRIKESAGASSHEVYLSPDICVCEDCLAELKDPDNRRFRYPYINCTNCGPRFTITVQVPYDRKHTTMRDFQLCPDCAKEYHDPTDRRFHAQPVACPVCGPSVSLLDASGKRVDLADAAACAAERLKSGAILAVKGLGGYHLACDATQETAVRELRSRKRRDGKPFAVMADTLETVLRICAVTEKERELLTSPKRPIVLLPLKTEARKLLPADTLSPDNNMLGVMLPYTPLQHLLFQDGLELMVMTSGNRSGEPIVYRDKEVTSALQGIADYYLVGDLPIHMRTDDTVTSVFREREYIIRRSRGYVPYPFDLTAVVQSAEVKPYKSGNSPILALGGELKNTFCLVKDRKAFVSHHIGDLDNLETLDSLIDGVAHFGRIFAAEAGVLAYDMHPGYRSSQYASVHKNIVKIPVQHHHAHIASCMAENGISGPVIGVAFDGTGLGEDGHVWGGEFFAGDYGGFERMAHFGYVPLPGGDAAVKEPWRMALSYLLNDEGTELPAHWLSTIEPYKRDIVNRQILQRINTPLTSSVGRLFDAVSSLTGLCHYAEYEGQAAIRLERAADRETSRIYPYEVKAVQGRLEIGAAPLIRELVLEIRDGRSISGISGAFHRTLAAIVGDICIRIRSERGLNEVALSGGVFQNRLLLAFTVDELERNGFRVWLHSKVPANDGGLSLGQAAIALGKYLTQEGMRESCVWQYPEK
>NZ_CP045298.1|WP_152381710.1|5072037_5072262_+|HypC/HybG/HupF-family-hydrogenase-formation-chaperone
MCLAIPGEVESVCGDKAVIDITGIRRQVSIALVDRVNVGDYLLVHAGCAIAIIDKQEAMETMELLHQLAGNIHD
>NZ_CP045298.1|WP_152382252.1|5072257_5073340_+|hydrogenase-formation-protein-HypD
MSELEKIQNQTLVEGLVKAIQRYDGKPVSIMEVCGTHTMAISRHGIRELLPPNVRLISGPGCPVCVTPSFYLKSALELGRREDTILATFGDMMRIPYKGVSLLTEKALGRDIRMVYSPLDSLDIARQHPDKKVIFLSVGFETTVPVTAIAVLEAAQQGLENFMILSANKTIPAAMHLLSSDPEVSVDGFMYPGHVSAVIGSGLYEELAKAYGIPGAITGFDPADILGSILYVLEQIRGNKATVANLYSKVVQPGGNPIAREKMDEVFEPSDAVWRGLGQIPGSGLRLREKYRAFDAWGLINGSVEEWDEEARGCRCGDILKGKCLPSDCKLFGKACTPETPVGSCMVSSEGTCTAYYRYQ
>NZ_CP045298.1|WP_152381711.1|5073354_5074365_+|hydrogenase-expression/formation-protein-HypE
MSEIITLAHGSGGKLTHQLIHGIFQKHFRNDWLLEGGDSAVLETLPGQLAFTTDSYVIHPLFFRGGNIGKLAICGTVNDLAVCGAIPRYISCAWIIEEGFALGELEEIAESMAATAKEAGVVIVTGDTKVVPRGCVDKLFINTSGVGFIPEGLRLSPALIRPGDRVIVTGTIGDHGTAILIEREQLQVETGLGSDCAPLNGMLELVTASMGGAVRLMRDPTRGGVATTLNEFTEGQSFGIRLEENALPVKGEVRGLCGMLGMDPLYIANEGKAILVVDGAQADRVIERLRSHPCGRDAAVIGEVVADHPGKVYMRTLAGGHRIIDMLVGDQLPRIC
>NZ_CP045298.1|WP_152381712.1|5074493_5075498_+|hypothetical-protein
MRRISASNGYVYFLVVLALHVLGGAGFLMATAREPKLWGLGLLAYTFGLRHAFDADHISAIDNTIRKLIERKRNPLGVGMYFSLGHSTVVFLMVLGIALSMNTFVLDNPKVREIGGLIGTLVSGFFLIFVGLINVFTLVNLWGRARGAANRTGRNFETGHMHGPRGMFTRFLAPAFRMINKSWHMYPLGFLFGLGFDTATEVSLLAISASTANESSSFISILSLPLLFAAGMSLMDTIDGAIMTRAYRWAFISYKKKTAYNLIVTGVSVVSAFFIGAVQLVHLIEAKWPQPAQWINRLGIDHLGYALAGFLILIWIVSMIIWRGMRGRHAVDGT
>NZ_CP045298.1|WP_152381713.1|5076129_5076303_+|recombinase-family-protein
MKIAYGRVSTKEQNIERQLLKFRELGIEERFVFVDKQSGKDFDRPRYQAMRLMLRVQ
>NZ_CP045298.1|WP_167518764.1|5076778_5077336_-|tyrosine-type-recombinase/integrase
MSRILRIVGVSEQIYYYRKKHHKILVSEEAVEEFLRFVAYDYGKQPELNKRHLSWYEDNRERDTAIVSLILGSGLRVNEVVNLILKDIDWEARCVLVTRKGKKMQSVPFLMRSKLDLEEYLRIRNSRYQPTVSETALFLTKGGKPMTKNAMQKMVNKYSRAYGKPLSVHILRHTFGTQLYKRKRI
>NZ_CP045298.1|WP_152381674.1|5077365_5077698_-|transposase
MQRRRFTMEFKQQVIQEAREVGNASQVARRHNINPKMLYRWMDQAEHTDWKTTDISAKAISAYAPSPQEFRALEGENKQLKEILGEKDLEIAVLRDLLKKQNPAYRTKLK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP045298_1	1.20\|1866184\|34\|NZ_CP045298\|CRISPRCasFinder,CRT,PILER-CR	1866184-1866217	34	NZ_CP045298.1	3588590-3588623	0	1.0
NZ_CP045298_1	1.21\|1866250\|37\|NZ_CP045298\|CRISPRCasFinder,CRT,PILER-CR	1866250-1866286	37	NZ_CP045298.1	3569843-3569879	0	1.0
NZ_CP045298_1	1.22\|1866319\|35\|NZ_CP045298\|CRISPRCasFinder,CRT,PILER-CR	1866319-1866353	35	NZ_CP045298.1	3476966-3477000	0	1.0
NZ_CP045298_3	3.2\|2713593\|36\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	2713593-2713628	36	NZ_CP045298.1	3626286-3626321	0	1.0
NZ_CP045298_3	3.15\|2714471\|34\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	2714471-2714504	34	NZ_CP045298.1	3574423-3574456	0	1.0
NZ_CP045298_7	7.1\|4517767\|35\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	4517767-4517801	35	NZ_CP045298.1	3476103-3476137	0	1.0
NZ_CP045298_7	7.2\|4517834\|34\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	4517834-4517867	34	NZ_CP045298.1	3634209-3634242	0	1.0
NZ_CP045298_7	7.3\|4517900\|36\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	4517900-4517935	36	NZ_CP045298.1	3554342-3554377	0	1.0
NZ_CP045298_8	8.1\|4528439\|37\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	4528439-4528475	37	NZ_CP045298.1	3570415-3570451	0	1.0
NZ_CP045298_8	8.2\|4528508\|34\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	4528508-4528541	34	NZ_CP045298.1	3603320-3603353	0	1.0
NZ_CP045298_11	11.1\|4537495\|33\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	4537495-4537527	33	NZ_CP045298.1	3546884-3546916	0	1.0
NZ_CP045298_11	11.2\|4537560\|37\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	4537560-4537596	37	NZ_CP045298.1	3548919-3548955	0	1.0
NZ_CP045298_11	11.3\|4537629\|38\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	4537629-4537666	38	NZ_CP045298.1	3560586-3560623	0	1.0
NZ_CP045298_11	11.20\|4538764\|36\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	4538764-4538799	36	NZ_CP045298.1	3634196-3634231	0	1.0
NZ_CP045298_9	9.5\|4530732\|37\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	4530732-4530768	37	NZ_CP045298.1	3657313-3657349	1	0.973

1. spacer 1.20|1866184|34|NZ_CP045298|CRISPRCasFinder,CRT,PILER-CR matches to position: 3588590-3588623, mismatch: 0, identity: 1.0

tttgcaatggctttagccgtttccttttcatcaa	CRISPR spacer
tttgcaatggctttagccgtttccttttcatcaa	Protospacer
**********************************

2. spacer 1.21|1866250|37|NZ_CP045298|CRISPRCasFinder,CRT,PILER-CR matches to position: 3569843-3569879, mismatch: 0, identity: 1.0

ttacctgttcccgcagcgtaggccacaccccccagga	CRISPR spacer
ttacctgttcccgcagcgtaggccacaccccccagga	Protospacer
*************************************

3. spacer 1.22|1866319|35|NZ_CP045298|CRISPRCasFinder,CRT,PILER-CR matches to position: 3476966-3477000, mismatch: 0, identity: 1.0

cgattcatcacgaaagagtagacgacaatcagaat	CRISPR spacer
cgattcatcacgaaagagtagacgacaatcagaat	Protospacer
***********************************

4. spacer 3.2|2713593|36|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to position: 3626286-3626321, mismatch: 0, identity: 1.0

acagaaatactccagcataaacgatatgttatcggt	CRISPR spacer
acagaaatactccagcataaacgatatgttatcggt	Protospacer
************************************

5. spacer 3.15|2714471|34|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to position: 3574423-3574456, mismatch: 0, identity: 1.0

gggcttgtgattcggtccggcggctcgctggatg	CRISPR spacer
gggcttgtgattcggtccggcggctcgctggatg	Protospacer
**********************************

6. spacer 7.1|4517767|35|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to position: 3476103-3476137, mismatch: 0, identity: 1.0

atccgagctgccagaggtactgggcttgtgtgacc	CRISPR spacer
atccgagctgccagaggtactgggcttgtgtgacc	Protospacer
***********************************

7. spacer 7.2|4517834|34|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to position: 3634209-3634242, mismatch: 0, identity: 1.0

cttgaaaccctgctcgattcgctcgtcgtacact	CRISPR spacer
cttgaaaccctgctcgattcgctcgtcgtacact	Protospacer
**********************************

8. spacer 7.3|4517900|36|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to position: 3554342-3554377, mismatch: 0, identity: 1.0

ctgtgaacagtaatcctgctgtacagatgtttattg	CRISPR spacer
ctgtgaacagtaatcctgctgtacagatgtttattg	Protospacer
************************************

9. spacer 8.1|4528439|37|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to position: 3570415-3570451, mismatch: 0, identity: 1.0

catggcgctctggtcattggtcgttgtcatcgctgcc	CRISPR spacer
catggcgctctggtcattggtcgttgtcatcgctgcc	Protospacer
*************************************

10. spacer 8.2|4528508|34|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to position: 3603320-3603353, mismatch: 0, identity: 1.0

tttgtcgaactcggaagttgtttcttccaattgt	CRISPR spacer
tttgtcgaactcggaagttgtttcttccaattgt	Protospacer
**********************************

11. spacer 11.1|4537495|33|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to position: 3546884-3546916, mismatch: 0, identity: 1.0

aaacctttatacgattttatacaatcgaatgaa	CRISPR spacer
aaacctttatacgattttatacaatcgaatgaa	Protospacer
*********************************

12. spacer 11.2|4537560|37|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to position: 3548919-3548955, mismatch: 0, identity: 1.0

gtatgtgggtgtgcacggctatgagatgggagccatc	CRISPR spacer
gtatgtgggtgtgcacggctatgagatgggagccatc	Protospacer
*************************************

13. spacer 11.3|4537629|38|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to position: 3560586-3560623, mismatch: 0, identity: 1.0

acgaaacggatcatcggctaacgacctacaaatatcgc	CRISPR spacer
acgaaacggatcatcggctaacgacctacaaatatcgc	Protospacer
**************************************

14. spacer 11.20|4538764|36|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to position: 3634196-3634231, mismatch: 0, identity: 1.0

aaacgggtgtcccagtgtacgacgagcgaatcgagc	CRISPR spacer
aaacgggtgtcccagtgtacgacgagcgaatcgagc	Protospacer
************************************

15. spacer 9.5|4530732|37|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to position: 3657313-3657349, mismatch: 1, identity: 0.973

tgttccagataataaacatctaacctggtacgtttgg	CRISPR spacer
tgttccagataataaacatctaccctggtacgtttgg	Protospacer
********************** **************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP045298_9	9.10\|4531076\|36\|NZ_CP045298\|CRT	4531076-4531111	36	NZ_CP010270	Paenibacillus polymyxa strain Sb3-1 plasmid pSb31l, complete sequence	125167-125202	0	1.0
NZ_CP045298_9	9.10\|4531076\|36\|NZ_CP045298\|CRT	4531076-4531111	36	NZ_CP011513	Paenibacillus peoriae strain HS311 plasmid unnamed, complete sequence	143111-143146	0	1.0
NZ_CP045298_7	7.10\|4518373\|33\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	4518373-4518405	33	NC_014628	Paenibacillus polymyxa SC2 plasmid pSC2, complete sequence	138219-138251	1	0.97
NZ_CP045298_7	7.11\|4518438\|35\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	4518438-4518472	35	NC_014628	Paenibacillus polymyxa SC2 plasmid pSC2, complete sequence	23004-23038	2	0.943
NZ_CP045298_7	7.23\|4519242\|37\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	4519242-4519278	37	NZ_CP040830	Paenibacillus polymyxa strain ZF129 plasmid pAP1, complete sequence	9942-9978	2	0.946
NZ_CP045298_10	10.14\|4536501\|36\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	4536501-4536536	36	NZ_CP040830	Paenibacillus polymyxa strain ZF129 plasmid pAP1, complete sequence	38355-38390	2	0.944
NZ_CP045298_11	11.17\|4538564\|33\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	4538564-4538596	33	NZ_CP038659	Citrobacter freundii strain 680 plasmid p680_1, complete sequence	381097-381129	5	0.848
NZ_CP045298_11	11.17\|4538564\|33\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	4538564-4538596	33	MN699848	Citrobacter pasteurii strain 175G8 plasmid pCfr-OXA-198, complete sequence	43992-44024	5	0.848
NZ_CP045298_11	11.1\|4537495\|33\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	4537495-4537527	33	NZ_CP048287	Paenibacillus sp. 14171R-81 plasmid unnamed1, complete sequence	196494-196526	6	0.818
NZ_CP045298_3	3.15\|2714471\|34\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	2714471-2714504	34	MG962366	Rhodococcus phage Finch, complete genome	4253-4286	7	0.794
NZ_CP045298_7	7.28\|4519579\|33\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	4519579-4519611	33	NZ_CP021071	Mesorhizobium sp. WSM1497 plasmid pWSM1497, complete sequence	168633-168665	7	0.788
NZ_CP045298_7	7.28\|4519579\|33\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	4519579-4519611	33	NZ_CP015063	Mesorhizobium ciceri strain CC1192 plasmid pMc1192, complete sequence	216672-216704	7	0.788
NZ_CP045298_7	7.28\|4519579\|33\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	4519579-4519611	33	NC_014918	Mesorhizobium ciceri biovar biserrulae WSM1271 plasmid pMESCI01, complete sequence	321470-321502	7	0.788
NZ_CP045298_8	8.2\|4528508\|34\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	4528508-4528541	34	NZ_CP054613	Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence	968407-968440	7	0.794
NZ_CP045298_3	3.7\|2713936\|34\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	2713936-2713969	34	MH884508	Bacillus phage vB_BcoS-136, complete genome	129664-129697	8	0.765
NZ_CP045298_3	3.11\|2714206\|34\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	2714206-2714239	34	NZ_CP039697	Novosphingobium sp. ABRDHK2 plasmid pABRDHK22, complete sequence	105035-105068	8	0.765
NZ_CP045298_8	8.10\|4529045\|33\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	4529045-4529077	33	NZ_CP022567	Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK03, complete sequence	342678-342710	8	0.758
NZ_CP045298_3	3.7\|2713936\|34\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	2713936-2713969	34	NC_025440	Listeria phage WIL-1, complete genome	78290-78323	9	0.735
NZ_CP045298_3	3.7\|2713936\|34\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	2713936-2713969	34	NC_047872	Listeria phage LMTA-94, complete genome	43839-43872	9	0.735
NZ_CP045298_3	3.7\|2713936\|34\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	2713936-2713969	34	KJ668715	Listeria phage LMTA-34, partial genome	30702-30735	9	0.735
NZ_CP045298_7	7.4\|4517968\|36\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	4517968-4518003	36	NC_015727	Cupriavidus necator N-1 plasmid pBB1, complete sequence	90269-90304	9	0.75
NZ_CP045298_7	7.24\|4519311\|34\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	4519311-4519344	34	NZ_LR214986	Mycoplasma cynos strain NCTC10142 plasmid 13	323197-323230	9	0.735
NZ_CP045298_9	9.5\|4530732\|37\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	4530732-4530768	37	NZ_KT897276	Clostridium botulinum strain INGR16-02E1 plasmid pINGR16-02E1, complete sequence	41687-41723	9	0.757
NZ_CP045298_9	9.5\|4530732\|37\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	4530732-4530768	37	NZ_KT897280	Clostridium botulinum strain FI1111E1 plasmid pFI1111E1, complete sequence	40598-40634	9	0.757
NZ_CP045298_9	9.5\|4530732\|37\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	4530732-4530768	37	NZ_KT897277	Clostridium botulinum strain ST0210E1 plasmid pST0210E1, complete sequence	41687-41723	9	0.757
NZ_CP045298_9	9.5\|4530732\|37\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	4530732-4530768	37	NZ_KT897278	Clostridium botulinum strain FWSKR40E1 plasmid pFWSKR40E1, complete sequence	40598-40634	9	0.757
NZ_CP045298_9	9.5\|4530732\|37\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	4530732-4530768	37	NZ_KT897279	Clostridium botulinum strain SWKR38E2 plasmid pSWKR38E2, complete sequence	40598-40634	9	0.757
NZ_CP045298_11	11.19\|4538698\|34\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	4538698-4538731	34	MN693287	Marine virus AFVG_25M168, complete genome	674-707	9	0.735
NZ_CP045298_1	1.18\|1866048\|37\|NZ_CP045298\|CRISPRCasFinder,CRT,PILER-CR	1866048-1866084	37	NC_010481	Acinetobacter baumannii plasmid pABIR, complete sequence	26426-26462	11	0.703
NZ_CP045298_1	1.18\|1866048\|37\|NZ_CP045298\|CRISPRCasFinder,CRT,PILER-CR	1866048-1866084	37	NZ_CP028557	Acinetobacter sp. WCHA45 plasmid p2_010045, complete sequence	3521-3557	11	0.703
NZ_CP045298_1	1.18\|1866048\|37\|NZ_CP045298\|CRISPRCasFinder,CRT,PILER-CR	1866048-1866084	37	KU500415	Acinetobacter baumannii strain JV1 plasmid ABA02, complete sequence	11785-11821	11	0.703

1. spacer 9.10|4531076|36|NZ_CP045298|CRT matches to NZ_CP010270 (Paenibacillus polymyxa strain Sb3-1 plasmid pSb31l, complete sequence) position: , mismatch: 0, identity: 1.0

catagcttttcgtcctccaggatacccaatgatctg	CRISPR spacer
catagcttttcgtcctccaggatacccaatgatctg	Protospacer
************************************

2. spacer 9.10|4531076|36|NZ_CP045298|CRT matches to NZ_CP011513 (Paenibacillus peoriae strain HS311 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

catagcttttcgtcctccaggatacccaatgatctg	CRISPR spacer
catagcttttcgtcctccaggatacccaatgatctg	Protospacer
************************************

3. spacer 7.10|4518373|33|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to NC_014628 (Paenibacillus polymyxa SC2 plasmid pSC2, complete sequence) position: , mismatch: 1, identity: 0.97

atcaatcgagtaggattcaaccaggtcactgta	CRISPR spacer
atcaatcgaataggattcaaccaggtcactgta	Protospacer
*********.***********************

4. spacer 7.11|4518438|35|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to NC_014628 (Paenibacillus polymyxa SC2 plasmid pSC2, complete sequence) position: , mismatch: 2, identity: 0.943

actaatgtttaaagcgaaggcttatagtgaacttc	CRISPR spacer
actaatgtttatagcgaaggcttacagtgaacttc	Protospacer
*********** ************.**********

5. spacer 7.23|4519242|37|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040830 (Paenibacillus polymyxa strain ZF129 plasmid pAP1, complete sequence) position: , mismatch: 2, identity: 0.946

agctcgggccacttggaaacctcatagagcgcttggc	CRISPR spacer
agctcgggccacttggaaacctcataaagggcttggc	Protospacer
**************************.** *******

6. spacer 10.14|4536501|36|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040830 (Paenibacillus polymyxa strain ZF129 plasmid pAP1, complete sequence) position: , mismatch: 2, identity: 0.944

ccgaagacgatctataataaggtttgcctcgtccac	CRISPR spacer
ccgaagacgatctataataaggtttgcctcatccat	Protospacer
******************************.****.

7. spacer 11.17|4538564|33|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038659 (Citrobacter freundii strain 680 plasmid p680_1, complete sequence) position: , mismatch: 5, identity: 0.848

ttttacgagatgccggaaatacctga--gtttact	CRISPR spacer
gtttacgagatgccctaaatacctgattgttta--	Protospacer
 *************  **********  *****

8. spacer 11.17|4538564|33|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to MN699848 (Citrobacter pasteurii strain 175G8 plasmid pCfr-OXA-198, complete sequence) position: , mismatch: 5, identity: 0.848

ttttacgagatgccggaaatacctga--gtttact	CRISPR spacer
gtttacgagatgccctaaatacctgattgttta--	Protospacer
 *************  **********  *****

9. spacer 11.1|4537495|33|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP048287 (Paenibacillus sp. 14171R-81 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.818

-aaacctttatacgattttatacaatcgaatgaa	CRISPR spacer
tccacctgt-tacgatttgatacaatcgaaggaa	Protospacer
   **** * ******** *********** ***

10. spacer 3.15|2714471|34|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to MG962366 (Rhodococcus phage Finch, complete genome) position: , mismatch: 7, identity: 0.794

gggcttgtgattcggtccggcggctcgctggatg	CRISPR spacer
gggcttgttattcggtgcggcggctctcaaggag	Protospacer
******** ******* ********* * .*. *

11. spacer 7.28|4519579|33|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021071 (Mesorhizobium sp. WSM1497 plasmid pWSM1497, complete sequence) position: , mismatch: 7, identity: 0.788

ttcgaacttgaccgcgtcggtaag--gcggttaag	CRISPR spacer
ttcgaacttgacctcgacggtaagcagcagctt--	Protospacer
************* ** *******  **.*.*

12. spacer 7.28|4519579|33|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015063 (Mesorhizobium ciceri strain CC1192 plasmid pMc1192, complete sequence) position: , mismatch: 7, identity: 0.788

ttcgaacttgaccgcgtcggtaag--gcggttaag	CRISPR spacer
ttcgaacttgacctcgacggtaagcagcagctt--	Protospacer
************* ** *******  **.*.*

13. spacer 7.28|4519579|33|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to NC_014918 (Mesorhizobium ciceri biovar biserrulae WSM1271 plasmid pMESCI01, complete sequence) position: , mismatch: 7, identity: 0.788

ttcgaacttgaccgcgtcggtaag--gcggttaag	CRISPR spacer
ttcgaacttgacctcgacggtaagcagcagctt--	Protospacer
************* ** *******  **.*.*

14. spacer 8.2|4528508|34|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP054613 (Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence) position: , mismatch: 7, identity: 0.794

tttgtcgaactcggaagttgtttcttccaattgt	CRISPR spacer
gcggtcgaagtcggaagttgtttcttccagctgc	Protospacer
 . ****** *******************..**.

15. spacer 3.7|2713936|34|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to MH884508 (Bacillus phage vB_BcoS-136, complete genome) position: , mismatch: 8, identity: 0.765

accgttaagctgtttaatccaaggtacaatacca	CRISPR spacer
attatttaattgtttaatccaaggtactacacca	Protospacer
*...** *..***************** *.****

16. spacer 3.11|2714206|34|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039697 (Novosphingobium sp. ABRDHK2 plasmid pABRDHK22, complete sequence) position: , mismatch: 8, identity: 0.765

cggtccagcgcgtgccggcgagtttgacgtcctc-	CRISPR spacer
cgatccagcgcgtgccggcgcg-ttgctgcgcgcg	Protospacer
**.***************** * *** .*. * *

17. spacer 8.10|4529045|33|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022567 (Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK03, complete sequence) position: , mismatch: 8, identity: 0.758

ctcgcatga-ccgccgactgtcgctcccggcgag	CRISPR spacer
-gcgagcggcccgccgactgccgcttccggcgag	Protospacer
  ** ..*. **********.****.********

18. spacer 3.7|2713936|34|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to NC_025440 (Listeria phage WIL-1, complete genome) position: , mismatch: 9, identity: 0.735

accgttaagctgtttaatccaaggtacaatacca	CRISPR spacer
gttgttcaactgtttaatccaaggtactgttcct	Protospacer
...*** *.****************** .* **

19. spacer 3.7|2713936|34|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to NC_047872 (Listeria phage LMTA-94, complete genome) position: , mismatch: 9, identity: 0.735

accgttaagctgtttaatccaaggtacaatacca	CRISPR spacer
gttgttcaactgtttaatccaaggtactgttcct	Protospacer
...*** *.****************** .* **

20. spacer 3.7|2713936|34|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to KJ668715 (Listeria phage LMTA-34, partial genome) position: , mismatch: 9, identity: 0.735

accgttaagctgtttaatccaaggtacaatacca	CRISPR spacer
gttgttcaactgtttaatccaaggtactgttcct	Protospacer
...*** *.****************** .* **

21. spacer 7.4|4517968|36|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to NC_015727 (Cupriavidus necator N-1 plasmid pBB1, complete sequence) position: , mismatch: 9, identity: 0.75

--tctctcaatctcgtcctgatctgcgtcaccgtcagt	CRISPR spacer
tgggcttcga--tcgtcctgatctgcgtaaccgccagt	Protospacer
    ..**.*  **************** ****.****

22. spacer 7.24|4519311|34|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR214986 (Mycoplasma cynos strain NCTC10142 plasmid 13) position: , mismatch: 9, identity: 0.735

tcacaatgaagcaagaagaatccttttttgttat	CRISPR spacer
gagcaatgaagcaaaaagaatacttttaacttaa	Protospacer
  .***********.****** *****   ***

23. spacer 9.5|4530732|37|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KT897276 (Clostridium botulinum strain INGR16-02E1 plasmid pINGR16-02E1, complete sequence) position: , mismatch: 9, identity: 0.757

tgttccagataataaacatctaacctggtacgtttgg	CRISPR spacer
ttatcgttataataagcatctaccctggtacgtttat	Protospacer
*  **   *******.****** ************.

24. spacer 9.5|4530732|37|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KT897280 (Clostridium botulinum strain FI1111E1 plasmid pFI1111E1, complete sequence) position: , mismatch: 9, identity: 0.757

tgttccagataataaacatctaacctggtacgtttgg	CRISPR spacer
ttatcgttataataagcatctaccctggtacgtttat	Protospacer
*  **   *******.****** ************.

25. spacer 9.5|4530732|37|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KT897277 (Clostridium botulinum strain ST0210E1 plasmid pST0210E1, complete sequence) position: , mismatch: 9, identity: 0.757

tgttccagataataaacatctaacctggtacgtttgg	CRISPR spacer
ttatcgttataataagcatctaccctggtacgtttat	Protospacer
*  **   *******.****** ************.

26. spacer 9.5|4530732|37|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KT897278 (Clostridium botulinum strain FWSKR40E1 plasmid pFWSKR40E1, complete sequence) position: , mismatch: 9, identity: 0.757

tgttccagataataaacatctaacctggtacgtttgg	CRISPR spacer
ttatcgttataataagcatctaccctggtacgtttat	Protospacer
*  **   *******.****** ************.

27. spacer 9.5|4530732|37|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KT897279 (Clostridium botulinum strain SWKR38E2 plasmid pSWKR38E2, complete sequence) position: , mismatch: 9, identity: 0.757

tgttccagataataaacatctaacctggtacgtttgg	CRISPR spacer
ttatcgttataataagcatctaccctggtacgtttat	Protospacer
*  **   *******.****** ************.

28. spacer 11.19|4538698|34|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to MN693287 (Marine virus AFVG_25M168, complete genome) position: , mismatch: 9, identity: 0.735

aaattctggttggttatattttgtgctgtcccat	CRISPR spacer
taattctgtttcgttatattttgtgcttggtaaa	Protospacer
 ******* ** ***************   . *

29. spacer 1.18|1866048|37|NZ_CP045298|CRISPRCasFinder,CRT,PILER-CR matches to NC_010481 (Acinetobacter baumannii plasmid pABIR, complete sequence) position: , mismatch: 11, identity: 0.703

ctacgaaaatataagcgactaaagcagtagacagtaa	CRISPR spacer
tgaaaaaaatataagcgaataaagtagtagagtagac	Protospacer
. * .************* *****.******  . *

30. spacer 1.18|1866048|37|NZ_CP045298|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP028557 (Acinetobacter sp. WCHA45 plasmid p2_010045, complete sequence) position: , mismatch: 11, identity: 0.703

ctacgaaaatataagcgactaaagcagtagacagtaa	CRISPR spacer
tgaaaaaaatataagcgaataaagtagtagagtagac	Protospacer
. * .************* *****.******  . *

31. spacer 1.18|1866048|37|NZ_CP045298|CRISPRCasFinder,CRT,PILER-CR matches to KU500415 (Acinetobacter baumannii strain JV1 plasmid ABA02, complete sequence) position: , mismatch: 11, identity: 0.703

ctacgaaaatataagcgactaaagcagtagacagtaa	CRISPR spacer
tgaaaaaaatataagcgaataaagtagtagagtagac	Protospacer
. * .************* *****.******  . *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

147585 : 301585

Paenibacillus_phage(28.57%)

transposase,protease

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_167518616.1\|147585_147750_-\|transposase	transposase	NA	NA	NA	NA
WP_152382067.1\|147770_148031_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_152378743.1\|148767_149307_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_152382068.1\|149320_150784_-	FAD-binding protein	NA	NA	NA	NA
WP_152378744.1\|151035_152496_-	MATE family efflux transporter	NA	NA	NA	NA
WP_167518617.1\|153029_169124_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_167518618.1\|169176_177846_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_152378747.1\|177838_189616_-	SDR family NAD(P)-dependent oxidoreductase	D0R7J2	Paenibacillus_phage	6.7e-37	30.8
WP_152378748.1\|189654_191943_-	ACP S-malonyltransferase	NA	NA	NA	NA
WP_152378750.1\|193194_194601_-	NADP-dependent phosphogluconate dehydrogenase	E3SPS4	Prochlorococcus_phage	9.2e-34	31.2
WP_025716139.1\|194774_195374_-	hypothetical protein	NA	NA	NA	NA
WP_025716138.1\|195370_195607_-	hypothetical protein	NA	NA	NA	NA
WP_152378751.1\|195652_196285_+	DUF1054 family protein	NA	NA	NA	NA
WP_152382069.1\|196309_197596_-	MFS transporter	NA	NA	NA	NA
WP_152378752.1\|197782_199258_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_007431055.1\|199369_199675_-	DUF1292 domain-containing protein	NA	NA	NA	NA
WP_152382070.1\|199754_200312_-	copper amine oxidase	NA	NA	NA	NA
WP_152378753.1\|200513_201275_+	MBL fold metallo-hydrolase	U5PU04	Bacillus_phage	6.7e-39	39.9
WP_025716132.1\|201393_201630_-	DUF3892 domain-containing protein	G3MB34	Bacillus_virus	8.8e-06	39.7
WP_152378754.1\|201732_202176_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_152378755.1\|202473_202608_-	hypothetical protein	NA	NA	NA	NA
WP_152378756.1\|203478_205197_+	oxaloacetate-decarboxylating malate dehydrogenase	NA	NA	NA	NA
WP_152378757.1\|205297_206257_+	AEC family transporter	NA	NA	NA	NA
WP_152378758.1\|206680_208444_+	HAMP domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	4.9e-08	70.2
WP_152378759.1\|208554_209607_-	arabinogalactan endo-1,4-beta-galactosidase	NA	NA	NA	NA
WP_152378760.1\|211790_212669_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_167518619.1\|216654_216807_+	hypothetical protein	NA	NA	NA	NA
WP_152378761.1\|216823_217261_-	DNA-entry nuclease	F8WPS9	Bacillus_phage	2.0e-35	65.4
WP_025716774.1\|217400_217598_+	hypothetical protein	NA	NA	NA	NA
WP_152378762.1\|217984_218287_+	hypothetical protein	NA	NA	NA	NA
WP_152378763.1\|218358_220245_-	tenascin	NA	NA	NA	NA
WP_025716776.1\|220366_220789_-	hypothetical protein	NA	NA	NA	NA
WP_025716777.1\|220805_221474_-	uracil-DNA glycosylase	A0A1R3T3N6	Sphenicid_alphaherpesvirus	6.9e-48	43.1
WP_152378764.1\|224725_226999_-	ACP S-malonyltransferase	NA	NA	NA	NA
WP_152378765.1\|227030_227984_-	acyltransferase domain-containing protein	NA	NA	NA	NA
WP_152378766.1\|228046_228916_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_152378767.1\|228977_236855_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_152378768.1\|236886_250305_-	SDR family NAD(P)-dependent oxidoreductase	D0R7J2	Paenibacillus_phage	1.4e-33	35.4
WP_152378769.1\|250355_270197_-	SDR family NAD(P)-dependent oxidoreductase	D0R7J2	Paenibacillus_phage	2.6e-33	29.4
WP_152378770.1\|270180_281364_-	amino acid adenylation domain-containing protein	D0R7J2	Paenibacillus_phage	2.1e-189	85.7
WP_025717359.1\|281654_282404_-	enoyl-CoA hydratase	NA	NA	NA	NA
WP_025717360.1\|282450_283212_-	enoyl-CoA hydratase/isomerase	NA	NA	NA	NA
WP_152378771.1\|283208_284471_-	3-hydroxy-3-methylglutaryl-ACP synthase	NA	NA	NA	NA
WP_152378772.1\|284486_285734_-	polyketide beta-ketoacyl:ACP synthase	NA	NA	NA	NA
WP_025717363.1\|285711_285951_-	acyl carrier protein	NA	NA	NA	NA
WP_152378773.1\|286072_286864_-	4'-phosphopantetheinyl transferase superfamily protein	NA	NA	NA	NA
WP_025717365.1\|286968_287490_-	antiterminator LoaP	NA	NA	NA	NA
WP_081752135.1\|287943_288579_-	MBL fold metallo-hydrolase	A0A1X9I5D3	Streptococcus_phage	9.3e-10	25.1
WP_152378774.1\|289382_290324_+	cysteine synthase A	A0A1X9I5K7	Streptococcus_phage	1.3e-84	53.6
WP_152378775.1\|291082_291637_+	hypothetical protein	NA	NA	NA	NA
WP_152378776.1\|291731_292304_-\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	6.8e-36	45.7
WP_152378777.1\|292237_292615_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_152378778.1\|292689_292896_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_167518620.1\|293118_294495_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_152378779.1\|295562_295871_-	DUF2500 family protein	NA	NA	NA	NA
WP_152378780.1\|296426_297353_-\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.9e-11	26.2
WP_152378781.1\|297343_297655_-\|transposase	transposase	NA	NA	NA	NA
WP_152378782.1\|300979_301585_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_2

577490 : 634934

Bacteriophage(16.67%)

integrase,transposase,protease,holin

attL 595708:595725|attR 623032:623049

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_152378940.1\|577490_578607_+\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	2.2e-115	72.5
WP_152378941.1\|578551_578932_-	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_152378942.1\|579158_579905_-	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_167518632.1\|580135_580279_-	hypothetical protein	NA	NA	NA	NA
WP_152378943.1\|580298_581180_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_152378944.1\|581497_582118_-	hypothetical protein	NA	NA	NA	NA
WP_010345194.1\|582381_582585_-	helix-turn-helix transcriptional regulator	A0A0C5ABM0	Bacteriophage	1.6e-11	50.0
WP_152378945.1\|582756_583044_+	hypothetical protein	NA	NA	NA	NA
WP_152378946.1\|583226_583703_-	hypothetical protein	NA	NA	NA	NA
WP_152378947.1\|585245_585977_-	hypothetical protein	NA	NA	NA	NA
WP_152378948.1\|586204_588001_-	hypothetical protein	NA	NA	NA	NA
WP_019686344.1\|588240_588444_-	helix-turn-helix transcriptional regulator	A0A0C5ABM0	Bacteriophage	4.1e-12	51.5
WP_152378949.1\|588615_588903_+	hypothetical protein	NA	NA	NA	NA
WP_152378950.1\|589126_589735_-	hypothetical protein	NA	NA	NA	NA
WP_152378951.1\|589916_590411_-	hypothetical protein	NA	NA	NA	NA
WP_152378952.1\|590780_591311_-	GNAT family N-acetyltransferase	A0A1B0RXL7	Streptococcus_phage	6.5e-41	46.1
WP_007431380.1\|591723_591816_-\|holin	putative holin-like toxin	NA	NA	NA	NA
WP_152378953.1\|592151_592580_-	hypothetical protein	NA	NA	NA	NA
WP_152378954.1\|592764_593148_-	SnoaL-like domain-containing protein	NA	NA	NA	NA
WP_152378955.1\|593855_594596_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_152378956.1\|594830_595337_-	DUF664 domain-containing protein	NA	NA	NA	NA
WP_152378957.1\|595547_596624_-	hypothetical protein	NA	NA	NA	NA
595708:595725	attL	NA	NA	NA	NA
WP_152378958.1\|596897_597251_-	hypothetical protein	NA	NA	NA	NA
WP_152378959.1\|597428_598196_-	hypothetical protein	NA	NA	NA	NA
WP_152378960.1\|598345_599341_-	hypothetical protein	NA	NA	NA	NA
WP_152378961.1\|599524_599992_-	DUF2691 family protein	NA	NA	NA	NA
WP_167518633.1\|600144_601158_-	hypothetical protein	NA	NA	NA	NA
WP_167518634.1\|601367_602339_-	hypothetical protein	NA	NA	NA	NA
WP_152378964.1\|602659_602884_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_152378965.1\|603037_603325_+	hypothetical protein	NA	NA	NA	NA
WP_152382084.1\|603504_603717_-	DUF3024 domain-containing protein	NA	NA	NA	NA
WP_152378966.1\|604071_604821_-	YfcE family phosphodiesterase	NA	NA	NA	NA
WP_152378967.1\|604960_605959_-\|integrase	tyrosine-type recombinase/integrase	S5W9T9	Leptospira_phage	4.0e-31	36.6
WP_152378968.1\|606332_608405_-	HAMP domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	3.8e-12	32.5
WP_152378969.1\|608696_609698_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_152378970.1\|609963_610515_-	hypothetical protein	NA	NA	NA	NA
WP_152378971.1\|610708_611266_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_152378972.1\|611292_612234_-	ADP-ribosylglycohydrolase family protein	A0A1S6UB21	Serratia_phage	2.8e-63	46.7
WP_152378973.1\|612647_613202_+	DUF1697 domain-containing protein	NA	NA	NA	NA
WP_152378974.1\|613389_613995_-	hypothetical protein	NA	NA	NA	NA
WP_152378975.1\|614296_615406_-	NADH:flavin oxidoreductase	NA	NA	NA	NA
WP_152378976.1\|615474_616056_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_152378977.1\|618824_619406_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_152378978.1\|619582_620326_+	SDR family NAD(P)-dependent oxidoreductase	A0A2P0VP75	Tetraselmis_virus	1.3e-07	27.6
WP_152378979.1\|620387_621209_+	SDR family NAD(P)-dependent oxidoreductase	W8CYX9	Bacillus_phage	7.1e-10	44.2
WP_025716921.1\|623493_624072_+	serine hydrolase family protein	NA	NA	NA	NA
623032:623049	attR	NA	NA	NA	NA
WP_152378980.1\|624137_626531_-	polyprenyl synthetase family protein	A0A1V0SE37	Indivirus	4.9e-11	26.6
WP_152378981.1\|630481_630931_-	ATP-binding cassette domain-containing protein	A0A1V0SE00	Indivirus	1.4e-15	39.5
WP_152378982.1\|630958_632080_-\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_152378983.1\|632164_633217_-	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	5.9e-17	26.5
WP_152378984.1\|633417_633846_-	hypothetical protein	NA	NA	NA	NA
WP_152378985.1\|633838_634147_-	hypothetical protein	NA	NA	NA	NA
WP_167518635.1\|634139_634451_-	hypothetical protein	NA	NA	NA	NA
WP_167518636.1\|634640_634934_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_3

775002 : 823882

uncultured_Caudovirales_phage(28.57%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_152379074.1\|775002_776040_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_152379075.1\|776345_776534_-	hypothetical protein	NA	NA	NA	NA
WP_167518639.1\|776673_776823_-	hypothetical protein	NA	NA	NA	NA
WP_152379076.1\|776827_777292_-	hypothetical protein	NA	NA	NA	NA
WP_152379077.1\|777483_778173_-	hypothetical protein	NA	NA	NA	NA
WP_152379078.1\|778197_778686_-	hypothetical protein	NA	NA	NA	NA
WP_152379079.1\|778793_780035_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_152379080.1\|780166_780385_-	hypothetical protein	NA	NA	NA	NA
WP_152379081.1\|780396_781173_-	recombinase family protein	A0A2H4J3Q1	uncultured_Caudovirales_phage	1.3e-18	27.1
WP_061828714.1\|781350_781560_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_152379082.1\|782079_782703_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_152379083.1\|783343_784024_-	hypothetical protein	NA	NA	NA	NA
WP_152379084.1\|784036_787375_-	hypothetical protein	NA	NA	NA	NA
WP_152379085.1\|787442_787865_-	DUF4280 domain-containing protein	NA	NA	NA	NA
WP_152379086.1\|787891_789316_-	hypothetical protein	NA	NA	NA	NA
WP_152379087.1\|789312_789930_-	hypothetical protein	NA	NA	NA	NA
WP_152379088.1\|790025_790793_-	DNA and RNA helicase	NA	NA	NA	NA
WP_152379089.1\|791154_791673_-	RDD family protein	NA	NA	NA	NA
WP_152379090.1\|791736_794388_-	molecular chaperone	NA	NA	NA	NA
WP_152379091.1\|794420_795110_-	iron-dependent peroxidase	NA	NA	NA	NA
WP_152379092.1\|795106_796426_-	normocyte-binding protein	NA	NA	NA	NA
WP_152379093.1\|796473_798360_-	serine/threonine protein phosphatase	NA	NA	NA	NA
WP_152379094.1\|798382_799213_-	SpoIIE family protein phosphatase	NA	NA	NA	NA
WP_152379095.1\|799249_799777_-	FHA domain-containing protein	NA	NA	NA	NA
WP_025716304.1\|799845_800394_-	FHA domain-containing protein	NA	NA	NA	NA
WP_152379096.1\|800426_800876_-	DnaJ domain-containing protein	E3T4P7	Cafeteria_roenbergensis_virus	4.6e-11	39.8
WP_152379097.1\|801006_801432_-\|protease	membrane-associated protease 1	NA	NA	NA	NA
WP_152382097.1\|801551_803720_-	transcriptional regulator	NA	NA	NA	NA
WP_152379098.1\|804358_806449_+	VWA domain-containing protein	NA	NA	NA	NA
WP_152379099.1\|806491_807403_-	protein kinase	A0A2I2L4T9	Orpheovirus	2.1e-15	32.9
WP_152379100.1\|807580_808846_-	MFS transporter	NA	NA	NA	NA
WP_152379101.1\|809038_809803_-	response regulator	A0A2R2ZGH8	Clostridioides_phage	3.3e-09	24.3
WP_152382098.1\|809799_811443_-	histidine kinase	Q9EYF3	Enterobacteria_phage	1.1e-51	27.7
WP_152379102.1\|811721_813218_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	2.6e-10	30.9
WP_152379103.1\|813470_814112_-	50S ribosomal protein L25	NA	NA	NA	NA
WP_152379104.1\|814324_815428_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	S6AND0	Bacillus_phage	6.3e-163	77.5
WP_167518640.1\|815680_815947_-	hypothetical protein	NA	NA	NA	NA
WP_167518641.1\|815970_816255_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_152382100.1\|816322_816976_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_152379105.1\|817028_817451_-	MFS transporter	NA	NA	NA	NA
WP_152379106.1\|817629_817968_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_152379107.1\|817999_818863_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_152379108.1\|818995_819655_-	type 1 glutamine amidotransferase domain-containing protein	NA	NA	NA	NA
WP_152379109.1\|820032_820329_+	NAD(P)-binding protein	NA	NA	NA	NA
WP_152379110.1\|820328_820511_+	NAD-binding protein	NA	NA	NA	NA
WP_152379111.1\|820491_820761_+	hypothetical protein	NA	NA	NA	NA
WP_152379112.1\|820775_821942_+	iron-containing alcohol dehydrogenase	NA	NA	NA	NA
WP_152382101.1\|821945_822263_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_152379113.1\|822378_822588_+	hypothetical protein	NA	NA	NA	NA
WP_152382102.1\|823228_823882_-\|transposase	IS630 family transposase	NA	NA	NA	NA

DBSCAN-SWA_4

1434586 : 1482380

Wolbachia_phage(22.22%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_152379494.1\|1434586_1435807_+\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	2.9e-52	31.9
WP_025719425.1\|1436674_1437259_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_152379495.1\|1437266_1438013_+	type I methionyl aminopeptidase	NA	NA	NA	NA
WP_152379496.1\|1438193_1438412_-	hypothetical protein	NA	NA	NA	NA
WP_152379497.1\|1438408_1441300_-	glycoside hydrolase family 81	A0A142C0M8	Faustovirus	6.6e-95	36.5
WP_152379498.1\|1441799_1442909_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	4.1e-53	38.0
WP_007432264.1\|1442905_1443670_-	GTP cyclohydrolase II	NA	NA	NA	NA
WP_152379499.1\|1443741_1444851_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_152379500.1\|1445106_1445442_+	transcriptional regulator	NA	NA	NA	NA
WP_025719419.1\|1445529_1445967_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_152379501.1\|1446121_1446640_+	DJ-1 family protein	NA	NA	NA	NA
WP_152379502.1\|1446674_1447580_-	DUF1835 domain-containing protein	NA	NA	NA	NA
WP_152379503.1\|1447748_1448450_+	DUF1275 family protein	NA	NA	NA	NA
WP_152379504.1\|1448459_1449635_-	hydrolase	NA	NA	NA	NA
WP_025719414.1\|1450275_1450836_-	NAD(P)H oxidoreductase	NA	NA	NA	NA
WP_152379505.1\|1450999_1451383_+	transcriptional regulator	NA	NA	NA	NA
WP_152379506.1\|1451676_1452450_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_152379507.1\|1452666_1453893_+	MFS transporter	NA	NA	NA	NA
WP_152379508.1\|1454438_1455476_-	aminotransferase class V-fold PLP-dependent enzyme	NA	NA	NA	NA
WP_049825229.1\|1455462_1455891_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_007432293.1\|1456067_1456238_-	hypothetical protein	NA	NA	NA	NA
WP_025719396.1\|1456257_1456452_-	H-type small acid-soluble spore protein	NA	NA	NA	NA
WP_152379509.1\|1456687_1457875_+	UDP-glucosyltransferase	Q0IKX4	Leucania_separata_nucleopolyhedrovirus	1.1e-08	28.2
WP_152379510.1\|1457903_1459442_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_152379511.1\|1460080_1460782_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_152379512.1\|1460879_1461620_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_152379513.1\|1461723_1462302_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_152382121.1\|1463222_1465004_-	response regulator	NA	NA	NA	NA
WP_152379514.1\|1465137_1465716_-	luciferase	NA	NA	NA	NA
WP_152379515.1\|1465917_1467267_-	erythromycin esterase family protein	NA	NA	NA	NA
WP_152379516.1\|1467528_1468410_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_152382122.1\|1468800_1470231_+\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_152379517.1\|1470502_1471984_-	sucrose-6-phosphate hydrolase	NA	NA	NA	NA
WP_152379518.1\|1471995_1473231_-	oligosaccharide MFS transporter	NA	NA	NA	NA
WP_167518657.1\|1473433_1474417_-	substrate-binding domain-containing protein	C6ZCU4	Enterobacteria_phage	3.9e-23	28.3
WP_152379520.1\|1474778_1475066_-	hypothetical protein	NA	NA	NA	NA
WP_152382123.1\|1475093_1475285_-	hypothetical protein	NA	NA	NA	NA
WP_152379522.1\|1477293_1478583_-	arsenical efflux pump membrane protein ArsB	A0A2H4PQU3	Staphylococcus_phage	2.5e-155	66.4
WP_152379494.1\|1479050_1480271_+\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	2.9e-52	31.9
WP_152379523.1\|1481144_1481489_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	1.5e-33	63.2
WP_152379524.1\|1481489_1482380_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	1.8e-43	55.8

DBSCAN-SWA_5

3108491 : 3120162

Mollivirus(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025719145.1\|3108491_3109790_+	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	5.3e-20	33.1
WP_167518700.1\|3110057_3110402_-	hypothetical protein	NA	NA	NA	NA
WP_152380478.1\|3110572_3111454_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0M4JBD3	Mollivirus	9.8e-42	34.6
WP_014279841.1\|3111515_3111761_+	phosphoribosylformylglycinamidine synthase subunit PurS	A0A0E3FJ99	Synechococcus_phage	1.4e-06	37.7
WP_025719141.1\|3111765_3112455_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_152380479.1\|3112432_3114676_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	8.0e-165	42.3
WP_025719138.1\|3114660_3116142_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	6.0e-52	31.6
WP_152380480.1\|3116853_3117894_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	7.7e-70	45.8
WP_152380481.1\|3117893_3118508_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	7.8e-22	35.9
WP_025719132.1\|3118614_3120162_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	1.5e-74	51.3

DBSCAN-SWA_6

3177013 : 3214483

uncultured_Caudovirales_phage(18.18%)

integrase,coat,transposase,terminase,portal

attL 3158386:3158420|attR 3230090:3230124

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3158386:3158420	attL	NA	NA	NA	NA
WP_152380518.1\|3177013_3177757_+\|transposase	transposase	A0A2H4JAE2	uncultured_Caudovirales_phage	4.4e-19	38.6
WP_152380519.1\|3177916_3178762_+\|integrase	tyrosine-type recombinase/integrase	A0A1B1IQT7	uncultured_Mediterranean_phage	2.9e-11	27.2
WP_152380520.1\|3180605_3180881_+	hypothetical protein	NA	NA	NA	NA
WP_152380521.1\|3181972_3183280_+\|portal	phage portal protein	A0A1V0DZW8	Clostridioides_phage	2.0e-54	31.7
WP_152380523.1\|3184059_3184680_+	DUF4355 domain-containing protein	S4UA71	Listeria_phage	2.1e-06	23.8
WP_152380524.1\|3184707_3185538_+\|coat	P22 coat protein - protein 5 domain protein	A0A1L2JY55	Aeribacillus_phage	4.0e-77	52.6
WP_152382168.1\|3185636_3185852_+	hypothetical protein	NA	NA	NA	NA
WP_152380525.1\|3185844_3186156_+	DNA-packaging protein	NA	NA	NA	NA
WP_152380526.1\|3186155_3186446_+	hypothetical protein	NA	NA	NA	NA
WP_152380527.1\|3186442_3187594_+	hypothetical protein	NA	NA	NA	NA
WP_152380528.1\|3187874_3189497_+	recombinase family protein	A0A2K5B2B4	Erysipelothrix_phage	1.9e-107	46.8
WP_152380529.1\|3190081_3190726_+	hypothetical protein	NA	NA	NA	NA
WP_167518701.1\|3190827_3191589_+	hypothetical protein	NA	NA	NA	NA
WP_167518702.1\|3192267_3192516_+	hypothetical protein	NA	NA	NA	NA
WP_152380531.1\|3193052_3193286_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_152380532.1\|3193820_3195779_+	N-6 DNA methylase	A0A220A2U4	Liberibacter_phage	1.1e-32	25.0
WP_152380533.1\|3195775_3196948_+	restriction endonuclease subunit S	NA	NA	NA	NA
WP_152380534.1\|3196961_3200090_+	HsdR family type I site-specific deoxyribonuclease	A0A220A398	Liberibacter_phage	3.8e-56	28.3
WP_152380535.1\|3200243_3200963_+	hypothetical protein	NA	NA	NA	NA
WP_152380536.1\|3201199_3204598_+	hypothetical protein	NA	NA	NA	NA
WP_165264052.1\|3204698_3204869_+	hypothetical protein	NA	NA	NA	NA
WP_152380537.1\|3204904_3206500_+	DNA/RNA helicase	NA	NA	NA	NA
WP_167518703.1\|3207112_3209266_+	hypothetical protein	NA	NA	NA	NA
WP_152380539.1\|3209497_3210763_+	ParB N-terminal domain-containing protein	A0A2I4R670	Erysipelothrix_phage	1.2e-109	49.4
WP_167518607.1\|3210802_3210943_+	hypothetical protein	NA	NA	NA	NA
WP_152380540.1\|3211008_3211752_+\|transposase	transposase	A0A2H4JAE2	uncultured_Caudovirales_phage	5.8e-19	37.9
WP_152380541.1\|3212932_3214483_+\|terminase	phage terminase large subunit	A0A0N7AEF1	Bacillus_phage	7.7e-74	33.7
3230090:3230124	attR	NA	NA	NA	NA

DBSCAN-SWA_7

3415240 : 3512083

Bacillus_phage(30.3%)

integrase,plate,transposase,bacteriocin,portal,tail,holin

attL 3467570:3467583|attR 3486455:3486469

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_152380661.1\|3415240_3416362_+\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_152380662.1\|3416666_3417128_-	penicillinase repressor	NA	NA	NA	NA
WP_167518708.1\|3417428_3418907_+	Cys-rich peptide radical SAM maturase CcpM	NA	NA	NA	NA
WP_152380664.1\|3418919_3419999_+	TIGR04066 family peptide maturation system protein	NA	NA	NA	NA
WP_152380665.1\|3420011_3420299_+	hypothetical protein	NA	NA	NA	NA
WP_152380666.1\|3420295_3420430_+\|bacteriocin	CLI_3235 family bacteriocin precursor	NA	NA	NA	NA
WP_152380667.1\|3420497_3421982_+	S8 family serine peptidase	NA	NA	NA	NA
WP_152380668.1\|3421983_3423657_+	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	1.3e-23	23.8
WP_152380669.1\|3425002_3425707_+	lysophospholipase	NA	NA	NA	NA
WP_152380670.1\|3427205_3428477_+	HAMP domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	2.0e-11	27.8
WP_152380671.1\|3428568_3428781_-	hypothetical protein	NA	NA	NA	NA
WP_152380672.1\|3428923_3429736_+	TIGR02206 family membrane protein	NA	NA	NA	NA
WP_152380673.1\|3429911_3431354_+	N-acyl-D-glucosamine 2-epimerase	NA	NA	NA	NA
WP_152380674.1\|3431989_3432667_-	peptidylprolyl isomerase	A0A1B1IVS0	uncultured_Mediterranean_phage	1.3e-22	46.6
WP_167518709.1\|3432782_3432953_+	hypothetical protein	NA	NA	NA	NA
WP_152380675.1\|3432997_3433255_-	DUF3886 domain-containing protein	NA	NA	NA	NA
WP_025716233.1\|3433420_3433600_+	aspartyl-phosphate phosphatase Spo0E family protein	NA	NA	NA	NA
WP_152382181.1\|3433617_3434523_-	EamA family transporter	NA	NA	NA	NA
WP_152380676.1\|3435391_3436402_+	substrate-binding domain-containing protein	NA	NA	NA	NA
WP_152380677.1\|3437050_3437809_+	hypothetical protein	NA	NA	NA	NA
WP_152380678.1\|3437816_3438788_+	sugar kinase	NA	NA	NA	NA
WP_152380679.1\|3438784_3440086_+	MFS transporter	NA	NA	NA	NA
WP_152380680.1\|3440082_3440832_+	3-hexulose-6-phosphate synthase	NA	NA	NA	NA
WP_152380681.1\|3440980_3441529_+	6-phospho-3-hexuloisomerase	NA	NA	NA	NA
WP_152380682.1\|3442894_3443746_+	TrmB family transcriptional regulator	NA	NA	NA	NA
WP_025716236.1\|3445243_3446326_-	bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase	A0A0F7L3G9	uncultured_marine_virus	2.3e-08	45.3
WP_152380683.1\|3447080_3447269_-	hypothetical protein	NA	NA	NA	NA
WP_152380684.1\|3447343_3447574_-	hypothetical protein	NA	NA	NA	NA
WP_152380685.1\|3448002_3449892_+	sensor histidine kinase	NA	NA	NA	NA
WP_152380686.1\|3449990_3450227_-	NHLP leader peptide family natural product precursor	NA	NA	NA	NA
WP_152380687.1\|3450302_3451238_-	hypothetical protein	NA	NA	NA	NA
WP_152380688.1\|3452654_3453167_+	hypothetical protein	NA	NA	NA	NA
WP_152380689.1\|3453830_3455057_-	acyltransferase family protein	NA	NA	NA	NA
WP_152380690.1\|3455270_3456278_+	substrate-binding domain-containing protein	NA	NA	NA	NA
WP_152382182.1\|3456354_3458337_+	histidine kinase	Q9EYF3	Enterobacteria_phage	1.8e-22	27.8
3456801:3456815	attL	NA	NA	NA	NA
WP_152380691.1\|3458299_3459568_+	response regulator	W8CYM9	Bacillus_phage	2.8e-05	30.9
3456801:3456815	attL	NA	NA	NA	NA
WP_025716246.1\|3459664_3460957_+	hydroxylamine reductase	NA	NA	NA	NA
WP_152380692.1\|3461174_3463286_+	hypothetical protein	NA	NA	NA	NA
WP_152380693.1\|3463288_3464803_+	hypothetical protein	NA	NA	NA	NA
WP_152380694.1\|3464922_3466185_+	DNA (cytosine-5-)-methyltransferase	M1PSQ0	Streptococcus_phage	4.7e-37	33.0
WP_152380695.1\|3466228_3467350_-\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_152380696.1\|3467575_3467881_+\|transposase	transposase	NA	NA	NA	NA
WP_167518710.1\|3467877_3468186_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_167518711.1\|3468255_3468459_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	A0A0P0I4A4	Acinetobacter_phage	5.6e-09	44.4
WP_152380699.1\|3468467_3468713_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	A0A2I6AZV9	Macacine_betaherpesvirus	5.3e-14	49.3
WP_152382183.1\|3468669_3468759_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_152380700.1\|3468905_3469253_-	helix-turn-helix domain-containing protein	B5LPU7	Bacillus_virus	3.8e-05	42.4
WP_152380701.1\|3470186_3470516_+	phosphoribosyl-ATP pyrophosphohydrolase	NA	NA	NA	NA
3469572:3469585	attR	NA	NA	NA	NA
WP_152382184.1\|3470502_3471333_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
3469572:3469585	attR	NA	NA	NA	NA
WP_152380702.1\|3471439_3472657_+	MFS transporter	NA	NA	NA	NA
WP_152380703.1\|3472676_3473273_+	hydrolase	NA	NA	NA	NA
WP_152380704.1\|3473588_3474674_+	substrate-binding domain-containing protein	NA	NA	NA	NA
WP_152380705.1\|3474708_3476259_+	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	6.2e-15	25.8
WP_152380706.1\|3476242_3477406_+	sugar ABC transporter permease	NA	NA	NA	NA
WP_152380707.1\|3477499_3478399_-	SDR family oxidoreductase	A0A2N9QUX2	Trichoplusia_ni_ascovirus	2.4e-51	41.9
WP_152380708.1\|3478460_3479213_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_025716259.1\|3479374_3479803_+	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_152380709.1\|3479859_3480378_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_152380710.1\|3480832_3482101_-	MFS transporter	NA	NA	NA	NA
WP_007429143.1\|3483892_3484390_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	1.7e-51	63.5
WP_152380711.1\|3484820_3485702_-	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	8.3e-57	44.6
WP_025716263.1\|3485694_3486186_-	6-carboxytetrahydropterin synthase QueD	J9PV91	Bacillus_phage	2.4e-58	69.9
WP_152380712.1\|3486178_3486862_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	1.6e-63	56.3
WP_152380713.1\|3487127_3487832_-	hypothetical protein	NA	NA	NA	NA
WP_152380714.1\|3487857_3488298_-	hypothetical protein	NA	NA	NA	NA
WP_167518712.1\|3488612_3488768_+	hypothetical protein	NA	NA	NA	NA
WP_152380715.1\|3488993_3489734_+	hypothetical protein	NA	NA	NA	NA
WP_152380716.1\|3489832_3490816_+	WYL domain-containing protein	NA	NA	NA	NA
WP_152380717.1\|3490856_3491528_-	exonuclease	NA	NA	NA	NA
WP_152380718.1\|3491727_3493629_-	LysM peptidoglycan-binding domain-containing protein	A0A2P1CFA9	Microbacterium_phage	9.0e-08	50.9
WP_152380719.1\|3493824_3494250_-	ImmA/IrrE family metallo-endopeptidase	A0A0S2SXM3	Bacillus_phage	3.1e-17	38.8
WP_152380720.1\|3494261_3494735_-	helix-turn-helix domain-containing protein	S6C481	Thermus_phage	2.1e-19	40.5
WP_007429156.1\|3495013_3495490_+	transcriptional regulator	A0A0C5AJ96	Bacteriophage	9.0e-42	61.9
WP_152382185.1\|3495680_3496544_+	aminoglycoside 6-adenylyltransferase	E4ZFP8	Streptococcus_phage	5.0e-91	54.6
WP_152380721.1\|3496878_3497847_+	hypothetical protein	NA	NA	NA	NA
WP_152380722.1\|3497857_3498076_+	hypothetical protein	NA	NA	NA	NA
WP_152380723.1\|3498078_3499545_+\|tail	phage tail sheath protein	A0A0N7AEC6	Bacillus_phage	3.1e-72	36.1
WP_007429163.1\|3499667_3500075_+\|tail	phage tail tube protein	A0A2H4J032	uncultured_Caudovirales_phage	3.2e-40	61.1
WP_007429164.1\|3500175_3500610_+	hypothetical protein	A0A2H4J883	uncultured_Caudovirales_phage	1.8e-20	42.0
WP_152380724.1\|3500786_3502529_+	hypothetical protein	NA	NA	NA	NA
WP_152380725.1\|3502565_3503207_+	LysM peptidoglycan-binding domain-containing protein	A0A0N7ACF7	Bacillus_phage	1.7e-43	52.3
WP_152380726.1\|3503203_3504181_+\|portal	phage portal protein	A0A0N6W8H4	Bacillus_phage	4.2e-78	47.4
WP_152380727.1\|3504173_3504581_+	hypothetical protein	A0A0N7ACD3	Bacillus_phage	8.6e-09	31.5
WP_025718321.1\|3504573_3505038_+	DUF2634 domain-containing protein	A0A0N7ACH4	Bacillus_phage	3.4e-25	38.6
WP_152380728.1\|3505037_3506189_+\|plate	Baseplate J family protein	S6AVU3	Thermus_phage	6.0e-39	34.4
WP_152382186.1\|3506235_3506805_+	DUF2313 domain-containing protein	A0A090D815	Clostridium_phage	1.1e-17	35.1
WP_152380729.1\|3506806_3509389_+	hypothetical protein	G9J201	Bacillus_phage	3.5e-23	26.5
WP_152380730.1\|3509405_3510017_+	hypothetical protein	NA	NA	NA	NA
WP_152380731.1\|3510078_3510348_+	hypothetical protein	NA	NA	NA	NA
WP_152380732.1\|3510506_3510953_+\|holin	holin	R9TMD4	Paenibacillus_phage	1.1e-41	60.4
WP_152380733.1\|3511117_3512083_+	1,4-beta-N-acetylmuramidase	D0R7H8	Paenibacillus_phage	1.3e-55	47.6

DBSCAN-SWA_8

3593045 : 3667133

104

Brevibacillus_phage(27.78%)

integrase,capsid,plate,transposase,terminase,tRNA,portal,tail,holin

attL 3659533:3659550|attR 3666594:3666611

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_152380793.1\|3593045_3593525_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	NA	NA	NA	NA
WP_152380794.1\|3593528_3594365_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA
WP_152380795.1\|3594382_3594898_+	ribosomal protein S18-alanine N-acetyltransferase	NA	NA	NA	NA
WP_152380796.1\|3594894_3595959_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	1.3e-59	38.0
WP_152380797.1\|3596510_3598475_-	ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	4.1e-56	29.6
WP_152380798.1\|3598746_3599382_+	5-formyltetrahydrofolate cyclo-ligase	NA	NA	NA	NA
WP_152380799.1\|3599439_3599928_+	cyclic pyranopterin monophosphate synthase MoaC	NA	NA	NA	NA
WP_013369877.1\|3600041_3600524_+	MogA/MoaB family molybdenum cofactor biosynthesis protein	NA	NA	NA	NA
WP_152380800.1\|3600582_3600834_+	twin-arginine translocase TatA/TatE family subunit	NA	NA	NA	NA
WP_152380801.1\|3600934_3601699_+	twin-arginine translocase subunit TatC	NA	NA	NA	NA
WP_025685233.1\|3601919_3602201_+	co-chaperone GroES	A0A221S3C8	uncultured_virus	6.3e-19	50.0
WP_010349766.1\|3602273_3603902_+	chaperonin GroEL	A0A219YK78	uncultured_virus	1.8e-158	57.6
WP_152380802.1\|3603968_3605165_-\|integrase	tyrosine-type recombinase/integrase	A0A0C5AN64	Paenibacillus_phage	9.3e-112	53.8
WP_152380803.1\|3605180_3606107_-	helix-turn-helix domain-containing protein	R9VW28	Paenibacillus_phage	1.9e-43	64.2
WP_019686451.1\|3606284_3606566_+	hypothetical protein	NA	NA	NA	NA
WP_152380804.1\|3606586_3606820_+	helix-turn-helix domain-containing protein	A0A0C5AN65	Paenibacillus_phage	1.4e-11	47.1
WP_152380805.1\|3606833_3607574_+	phage antirepressor Ant	R9VWW9	Paenibacillus_phage	1.0e-52	58.0
WP_152380806.1\|3607576_3607843_+	hypothetical protein	NA	NA	NA	NA
WP_152380807.1\|3607845_3608034_+	hypothetical protein	NA	NA	NA	NA
WP_152380808.1\|3608188_3608383_+	hypothetical protein	NA	NA	NA	NA
WP_167518715.1\|3608384_3608537_+	hypothetical protein	NA	NA	NA	NA
WP_152380809.1\|3608683_3608920_+	hypothetical protein	NA	NA	NA	NA
WP_152380810.1\|3608965_3609844_+	hypothetical protein	A0A0A7RUE9	Clostridium_phage	1.0e-83	60.2
WP_152380811.1\|3609830_3610631_+	hypothetical protein	A0A0A7RVR3	Clostridium_phage	7.8e-46	41.0
WP_152380812.1\|3610645_3611071_+	single-stranded DNA-binding protein	A0A0K2CYR2	Paenibacillus_phage	3.6e-50	70.4
WP_152380813.1\|3611089_3611425_+	hypothetical protein	NA	NA	NA	NA
WP_167518716.1\|3612433_3613084_+	ATP-binding protein	A0A1B1P7U2	Bacillus_phage	5.6e-26	34.9
WP_152380815.1\|3613109_3613385_+	hypothetical protein	NA	NA	NA	NA
WP_152380816.1\|3613381_3613732_+	DUF551 domain-containing protein	NA	NA	NA	NA
WP_152380817.1\|3613767_3614160_+	hypothetical protein	NA	NA	NA	NA
WP_167518717.1\|3614156_3614318_+	hypothetical protein	NA	NA	NA	NA
WP_152380818.1\|3614277_3614655_+	RusA family crossover junction endodeoxyribonuclease	A0A0K2CYQ8	Paenibacillus_phage	1.0e-35	52.5
WP_152380819.1\|3614666_3615260_+	sigma-70 family RNA polymerase sigma factor	A0A076FMK8	Aureococcus_anophage	6.2e-08	41.8
WP_152380820.1\|3615326_3615539_+	hypothetical protein	NA	NA	NA	NA
WP_152380821.1\|3615558_3615954_+	hypothetical protein	NA	NA	NA	NA
WP_152380822.1\|3616016_3616877_+	DNA (cytosine-5-)-methyltransferase	A0A218MKT0	uncultured_virus	8.7e-11	23.2
WP_152380823.1\|3616942_3617152_+	hypothetical protein	NA	NA	NA	NA
WP_152380824.1\|3617186_3617663_+	hypothetical protein	A0A059VFZ8	Pseudomonas_phage	1.2e-25	42.1
WP_152380825.1\|3617721_3617907_+	hypothetical protein	S5MP11	Brevibacillus_phage	8.9e-14	60.7
WP_152380826.1\|3617941_3618187_+	hypothetical protein	NA	NA	NA	NA
WP_152380827.1\|3618251_3618563_+	hypothetical protein	NA	NA	NA	NA
WP_152380828.1\|3618695_3619100_+	hypothetical protein	NA	NA	NA	NA
WP_152380829.1\|3619141_3619486_+	hypothetical protein	NA	NA	NA	NA
WP_152380830.1\|3619565_3619937_+	hypothetical protein	NA	NA	NA	NA
WP_152380831.1\|3619933_3620560_+	hypothetical protein	NA	NA	NA	NA
WP_152380832.1\|3620671_3620881_+	hypothetical protein	NA	NA	NA	NA
WP_152380833.1\|3620892_3621414_+	RNA polymerase subunit sigma-24	A0A1L2JY33	Aeribacillus_phage	8.7e-30	43.4
WP_152380834.1\|3621573_3622515_+	glycosyl hydrolase	NA	NA	NA	NA
WP_152380835.1\|3622659_3622911_+	hypothetical protein	NA	NA	NA	NA
WP_152380836.1\|3623010_3623238_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_152380837.1\|3623864_3624392_+	hypothetical protein	U5PUJ8	Bacillus_phage	5.2e-14	47.2
WP_152380838.1\|3624434_3624884_+\|terminase	terminase small subunit	A0A0K2CNQ5	Brevibacillus_phage	4.8e-37	55.9
WP_152380839.1\|3624864_3626124_+\|terminase	PBSX family phage terminase large subunit	S5MC58	Brevibacillus_phage	2.0e-197	79.8
WP_152380840.1\|3626138_3627608_+\|portal	phage portal protein	A0A0K2CNK4	Brevibacillus_phage	8.4e-155	60.3
WP_152380841.1\|3627604_3629314_+\|capsid	minor capsid protein	X5JAI9	Clostridium_phage	1.9e-94	50.1
WP_152380842.1\|3629480_3630107_+	hypothetical protein	S5M9M5	Brevibacillus_phage	2.2e-48	52.9
WP_152380843.1\|3630124_3630493_+	hypothetical protein	A0A0K2CNR0	Brevibacillus_phage	1.7e-40	70.2
WP_152380844.1\|3630511_3631558_+\|capsid	phage capsid protein	S5MNB6	Brevibacillus_phage	1.3e-141	71.2
WP_152380845.1\|3631603_3631918_+	hypothetical protein	NA	NA	NA	NA
WP_152380846.1\|3631877_3632252_+	hypothetical protein	A0A0A7RTF6	Clostridium_phage	1.3e-14	38.3
WP_152380847.1\|3632254_3632626_+	hypothetical protein	S5M673	Brevibacillus_phage	2.1e-14	40.4
WP_152380848.1\|3632622_3632886_+	HK97 gp10 family phage protein	A0A0A7RVN8	Clostridium_phage	2.7e-11	42.5
WP_152380849.1\|3634149_3634575_+	hypothetical protein	S5MBU4	Brevibacillus_phage	6.4e-31	47.9
WP_152380850.1\|3634567_3634816_+	hypothetical protein	NA	NA	NA	NA
WP_152380851.1\|3634812_3636138_+\|tail	phage tail sheath protein	S5MUG6	Brevibacillus_phage	2.7e-120	50.7
WP_064795248.1\|3636139_3636613_+\|tail	phage tail tube protein	A0A0K2CNG3	Brevibacillus_phage	2.1e-46	58.6
WP_152380852.1\|3636642_3637065_+\|portal	phage portal protein	X5JAB6	Clostridium_phage	1.6e-21	39.0
WP_152380853.1\|3637297_3637924_+	hypothetical protein	NA	NA	NA	NA
WP_152380854.1\|3637987_3640348_+	hypothetical protein	A0A0K2CP22	Brevibacillus_phage	6.4e-72	30.3
WP_152380855.1\|3640368_3640602_+	hypothetical protein	NA	NA	NA	NA
WP_152380856.1\|3640579_3640846_-	hypothetical protein	NA	NA	NA	NA
WP_152382190.1\|3641017_3641653_+	LysM peptidoglycan-binding domain-containing protein	S5MUH0	Brevibacillus_phage	4.9e-35	43.7
WP_152380857.1\|3641657_3642656_+	hypothetical protein	S5MNC9	Brevibacillus_phage	8.4e-98	54.1
WP_152380858.1\|3642659_3643019_+	DUF2577 family protein	A0A0A7RTJ2	Clostridium_phage	8.4e-16	39.3
WP_152380859.1\|3643015_3643423_+	DUF2634 domain-containing protein	S5MTX3	Brevibacillus_phage	1.0e-25	46.6
WP_152380860.1\|3643415_3644483_+\|plate	baseplate J protein	S6AVU3	Thermus_phage	2.8e-75	45.6
WP_152380861.1\|3644469_3645024_+	DUF2313 domain-containing protein	A0A0A7RUW8	Clostridium_phage	7.6e-24	34.3
WP_152380862.1\|3645016_3647524_+	hypothetical protein	S5YQ95	Bacillus_phage	4.5e-07	29.2
WP_152380863.1\|3647538_3648054_+	hypothetical protein	NA	NA	NA	NA
WP_152380864.1\|3648284_3648782_+\|holin	holin	M9Q253	Clostridium_phage	7.8e-20	40.8
WP_167518718.1\|3648729_3649512_+	M15 family metallopeptidase	U5PWQ2	Bacillus_phage	3.2e-36	51.3
WP_152380866.1\|3649514_3650075_+	hypothetical protein	D0R7H9	Paenibacillus_phage	1.4e-62	75.3
WP_152382191.1\|3650430_3650907_+	DUF4065 domain-containing protein	A0A0N9SGM1	Paenibacillus_phage	1.8e-26	42.2
WP_152380867.1\|3650899_3651553_+	hypothetical protein	NA	NA	NA	NA
WP_152380868.1\|3651634_3652081_+	nuclease	F8WPS9	Bacillus_phage	2.3e-39	68.6
WP_152380869.1\|3652146_3652401_+	hypothetical protein	NA	NA	NA	NA
WP_152380870.1\|3652500_3652716_+	hypothetical protein	NA	NA	NA	NA
WP_152380871.1\|3653518_3654934_+	transcriptional regulator	NA	NA	NA	NA
WP_152380872.1\|3655139_3655328_-	hypothetical protein	NA	NA	NA	NA
WP_152380873.1\|3655340_3655544_-	hypothetical protein	A0A0C5AEJ6	Paenibacillus_phage	5.0e-18	65.7
WP_152380874.1\|3655543_3655969_-	type II toxin-antitoxin system HicB family antitoxin	A0A090DBV2	Clostridium_phage	3.1e-33	53.0
WP_152380875.1\|3655998_3656193_-	addiction module toxin, HicA family	A0A1L2JY37	Aeribacillus_phage	1.4e-17	66.1
WP_152382192.1\|3656315_3656657_-	DUF3862 domain-containing protein	A0A218KCL9	Bacillus_phage	3.1e-12	58.5
WP_152380876.1\|3657290_3657659_-	Spo0E family sporulation regulatory protein-aspartic acid phosphatase	NA	NA	NA	NA
WP_152382193.1\|3657897_3658278_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_152380877.1\|3658549_3658789_+	oxidoreductase	NA	NA	NA	NA
3659533:3659550	attL	NA	NA	NA	NA
WP_152380878.1\|3659572_3661060_-	ABC-F type ribosomal protection protein	A0A2H4UUX5	Bodo_saltans_virus	1.2e-23	24.9
WP_152380879.1\|3661910_3662792_+	glycosyltransferase	A0A0F7L2F7	uncultured_marine_virus	5.4e-08	31.8
WP_152380880.1\|3663295_3663586_-	hypothetical protein	NA	NA	NA	NA
WP_152380881.1\|3663598_3664243_-	hypothetical protein	NA	NA	NA	NA
WP_152380882.1\|3664504_3665803_+	transcriptional regulator	NA	NA	NA	NA
WP_167518719.1\|3665996_3666296_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	A0A1B1P773	Bacillus_phage	8.5e-30	67.1
WP_152380884.1\|3666348_3666624_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	8.1e-11	46.8
3666594:3666611	attR	NA	NA	NA	NA
WP_152380885.1\|3666620_3667133_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_9

3997084 : 4047574

uncultured_Caudovirales_phage(25.0%)

transposase,integrase

attL 4040639:4040656|attR 4056478:4056495

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_152382207.1\|3997084_3998373_-\|transposase	IS3 family transposase	A0A0C5AC89	Paenibacillus_phage	3.5e-32	38.0
WP_152381088.1\|3998556_3999003_-	hypothetical protein	NA	NA	NA	NA
WP_152381089.1\|3999231_4000605_+	transcriptional regulator	NA	NA	NA	NA
WP_152381090.1\|4000779_4001559_+	TetR family transcriptional regulator	NA	NA	NA	NA
WP_025715957.1\|4001616_4002780_+	UDP-glucoronosyl and UDP-glucosyl transferase	NA	NA	NA	NA
WP_152381091.1\|4002822_4003944_-\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_152381092.1\|4004482_4004896_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_167518724.1\|4005375_4006320_+	MBL fold metallo-hydrolase	A0A1V0SGC6	Hokovirus	3.2e-06	21.8
WP_152381094.1\|4006372_4007350_+	aldo/keto reductase	NA	NA	NA	NA
WP_152381095.1\|4007624_4008479_+\|integrase	tyrosine-type recombinase/integrase	A0A1P8DJP1	Virus_Rctr41k	2.0e-07	23.2
WP_152381096.1\|4009219_4010617_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_167518725.1\|4010908_4011145_+	hypothetical protein	NA	NA	NA	NA
WP_152381097.1\|4011318_4012542_+	WXG100 family type VII secretion target	NA	NA	NA	NA
WP_071558868.1\|4012558_4012843_+	hypothetical protein	NA	NA	NA	NA
WP_152381098.1\|4013059_4013614_+	hypothetical protein	NA	NA	NA	NA
WP_167518726.1\|4014176_4014452_+	hypothetical protein	NA	NA	NA	NA
WP_152381099.1\|4014560_4015259_+	WXG100 family type VII secretion target	NA	NA	NA	NA
WP_152381100.1\|4015306_4015531_+	hypothetical protein	NA	NA	NA	NA
WP_152382208.1\|4015537_4015753_+	hypothetical protein	NA	NA	NA	NA
WP_152381101.1\|4015752_4016103_+	hypothetical protein	NA	NA	NA	NA
WP_152381102.1\|4016243_4016441_+	hypothetical protein	NA	NA	NA	NA
WP_152381103.1\|4016804_4017296_+	hypothetical protein	NA	NA	NA	NA
WP_152381104.1\|4017341_4017635_+	hypothetical protein	NA	NA	NA	NA
WP_167518727.1\|4017737_4018571_+	hypothetical protein	NA	NA	NA	NA
WP_152381106.1\|4018621_4018987_+	hypothetical protein	A0A0A0RP18	Bacillus_phage	1.1e-28	55.5
WP_152381107.1\|4019860_4020097_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_152381108.1\|4020962_4021409_+	hypothetical protein	NA	NA	NA	NA
WP_152381109.1\|4021841_4022552_+	zinc-ribbon domain-containing protein	NA	NA	NA	NA
WP_152381110.1\|4023228_4023546_+	hypothetical protein	NA	NA	NA	NA
WP_019687609.1\|4025071_4025236_+	hypothetical protein	NA	NA	NA	NA
WP_152381111.1\|4025339_4026056_+	hypothetical protein	NA	NA	NA	NA
WP_152381112.1\|4026108_4026423_+	hypothetical protein	NA	NA	NA	NA
WP_152381113.1\|4026785_4027259_+	hypothetical protein	NA	NA	NA	NA
WP_063208297.1\|4028203_4028881_+	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_142613176.1\|4028940_4029138_+	DUF2892 domain-containing protein	NA	NA	NA	NA
WP_063208301.1\|4029154_4029535_+	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_152381114.1\|4029801_4030512_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_152382209.1\|4030517_4030748_+	DUF3102 domain-containing protein	A0A2H4JAH5	uncultured_Caudovirales_phage	8.3e-09	67.5
WP_025721418.1\|4031444_4032062_+	recombinase family protein	A0A219YA40	Aeromonas_phage	3.0e-13	28.1
WP_152381115.1\|4032805_4034176_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_167518728.1\|4034394_4034580_+	hypothetical protein	NA	NA	NA	NA
WP_152381116.1\|4034788_4036048_+	WXG100 family type VII secretion target	NA	NA	NA	NA
WP_152381117.1\|4036048_4036378_+	hypothetical protein	NA	NA	NA	NA
WP_152381118.1\|4036515_4037439_-\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	3.6e-10	28.4
WP_152378781.1\|4037429_4037741_-\|transposase	transposase	NA	NA	NA	NA
WP_152381119.1\|4037991_4039389_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
4040639:4040656	attL	NA	NA	NA	NA
WP_167518794.1\|4040775_4041117_+	hypothetical protein	NA	NA	NA	NA
WP_167518729.1\|4041609_4042323_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_152381122.1\|4042411_4044316_+	hypothetical protein	NA	NA	NA	NA
WP_167518730.1\|4044662_4044824_+	hypothetical protein	NA	NA	NA	NA
WP_152381123.1\|4044915_4045722_+	hypothetical protein	NA	NA	NA	NA
WP_013309546.1\|4046162_4046348_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_152381124.1\|4046446_4047574_+\|integrase	tyrosine-type recombinase/integrase	A0A2H4JCB7	uncultured_Caudovirales_phage	5.2e-56	33.9
4056478:4056495	attR	NA	NA	NA	NA

DBSCAN-SWA_10

4104632 : 4113949

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_167518731.1\|4104632_4105502_+	glucose 1-dehydrogenase	A0A2N9QUX2	Trichoplusia_ni_ascovirus	1.3e-51	41.1
WP_152381164.1\|4105612_4107415_+	HAMP domain-containing protein	W8CYF6	Bacillus_phage	9.3e-39	36.3
WP_010349065.1\|4107544_4108276_+	response regulator transcription factor	W8CYM9	Bacillus_phage	1.6e-37	35.3
WP_152381165.1\|4108408_4109533_+	CBS domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	6.5e-06	33.7
WP_152381166.1\|4109660_4110419_+	phosphate ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	3.0e-15	33.5
WP_152381167.1\|4110457_4111117_+	phosphate signaling complex protein PhoU	NA	NA	NA	NA
WP_152381168.1\|4111294_4113949_+	DNA polymerase I	A0A060AM05	Listeria_phage	6.2e-47	30.1

DBSCAN-SWA_11

4938524 : 4965218

Escherichia_phage(25.0%)

transposase,integrase

attL 4939897:4939913|attR 4963440:4963456

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_152382242.1\|4938524_4938722_-\|transposase	transposase	NA	NA	NA	NA
WP_152381621.1\|4938820_4939708_-	substrate-binding domain-containing protein	NA	NA	NA	NA
4939897:4939913	attL	NA	NA	NA	NA
WP_152381623.1\|4941821_4942445_-\|integrase	tyrosine-type recombinase/integrase	A0A2L1IV36	Escherichia_phage	4.7e-06	26.5
WP_152382243.1\|4942713_4943199_-	NUDIX domain-containing protein	NA	NA	NA	NA
WP_152381624.1\|4943395_4944157_-	SUMF1/EgtB/PvdO family nonheme iron enzyme	A0A7F1	Microcystis_virus	2.0e-27	38.9
WP_152381625.1\|4947976_4949321_+\|transposase	IS3 family transposase	A0A0C5AC89	Paenibacillus_phage	1.3e-32	38.4
WP_152381626.1\|4949785_4950931_-	glycosyltransferase	NA	NA	NA	NA
WP_152381627.1\|4951092_4951884_+	hypothetical protein	NA	NA	NA	NA
WP_152382244.1\|4952019_4953450_+\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_152381628.1\|4953569_4954922_-	DUF4158 domain-containing protein	NA	NA	NA	NA
WP_152381629.1\|4955294_4956266_+	WYL domain-containing protein	NA	NA	NA	NA
WP_152381630.1\|4956346_4956766_+	RidA family protein	NA	NA	NA	NA
WP_152381631.1\|4956772_4957378_+	DUF1697 domain-containing protein	NA	NA	NA	NA
WP_152381632.1\|4957424_4957958_+	damage-inducible protein DinB	NA	NA	NA	NA
WP_167518752.1\|4958968_4959892_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_167518753.1\|4963039_4963405_+	YolD-like family protein	NA	NA	NA	NA
WP_152381634.1\|4963997_4965218_+\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	5.9e-53	32.1
4963440:4963456	attR	NA	NA	NA	NA

DBSCAN-SWA_12

5009925 : 5037754

Paenibacillus_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_152381660.1\|5009925_5011146_+\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	1.3e-52	32.1
WP_152381661.1\|5011580_5012192_+	DUF2239 family protein	NA	NA	NA	NA
WP_152381662.1\|5012245_5012686_+	DUF1330 domain-containing protein	NA	NA	NA	NA
WP_152381663.1\|5012704_5013595_+	alpha/beta fold hydrolase	A0A1J0GP80	Mycobacterium_phage	4.2e-08	28.5
WP_152381664.1\|5014709_5016641_+	fructose-bisphosphatase class III	NA	NA	NA	NA
WP_167518757.1\|5018251_5018428_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_167518758.1\|5018462_5018774_+	winged helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_152381666.1\|5019125_5019530_+	hypothetical protein	NA	NA	NA	NA
WP_167518759.1\|5019586_5019841_+	hypothetical protein	NA	NA	NA	NA
WP_152381668.1\|5020050_5020308_+	hypothetical protein	NA	NA	NA	NA
WP_152381669.1\|5020628_5021576_+	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	4.9e-23	30.4
WP_025718058.1\|5021588_5022365_+	ABC transporter permease	NA	NA	NA	NA
WP_152381670.1\|5022361_5023348_+	ABC transporter permease	NA	NA	NA	NA
WP_152381671.1\|5023415_5026034_+	AAA family ATPase	NA	NA	NA	NA
WP_152381672.1\|5029242_5030006_-\|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	1.3e-37	59.8
WP_152381673.1\|5030794_5031070_+	hypothetical protein	NA	NA	NA	NA
WP_152381674.1\|5031445_5031778_+\|transposase	transposase	NA	NA	NA	NA
WP_167518760.1\|5031807_5032701_+\|transposase	IS3 family transposase	A0A0C5AEA5	Paenibacillus_phage	7.4e-13	27.1
WP_152381676.1\|5032861_5033146_+\|transposase	transposase	A0A0C5AJ30	Paenibacillus_phage	3.9e-24	64.8
WP_152381677.1\|5033151_5033877_+\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	6.1e-82	64.3
WP_152382248.1\|5034982_5035693_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_152380558.1\|5036525_5036837_+\|transposase	transposase	NA	NA	NA	NA
WP_152381678.1\|5036827_5037754_+\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.1e-11	27.9

DBSCAN-SWA_13

5051026 : 5101859

uncultured_Mediterranean_phage(16.67%)

integrase,transposase,protease

attL 5076299:5076314|attR 5096896:5096911

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_152381691.1\|5051026_5052148_-\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_152381692.1\|5052401_5053037_-	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_152381693.1\|5053058_5054204_-	MFS transporter	NA	NA	NA	NA
WP_152381694.1\|5054363_5055026_-	DedA family protein	NA	NA	NA	NA
WP_152381695.1\|5054986_5055820_-	hypothetical protein	NA	NA	NA	NA
WP_152381696.1\|5055816_5056323_-	hypothetical protein	NA	NA	NA	NA
WP_152381697.1\|5056324_5056858_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_152381698.1\|5056902_5058168_-	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_152381699.1\|5058441_5059062_-	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_167518763.1\|5059614_5060937_+	hypothetical protein	NA	NA	NA	NA
WP_152381701.1\|5061343_5061505_-	MerR family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_152381702.1\|5064058_5064946_+	hydrogenase small subunit	NA	NA	NA	NA
WP_152382251.1\|5064973_5066392_+	Ni,Fe-hydrogenase I large subunit	NA	NA	NA	NA
WP_152381703.1\|5066394_5066871_+\|protease	hydrogenase maturation protease	NA	NA	NA	NA
WP_152381704.1\|5066863_5067205_+	hydrogenase maturation nickel metallochaperone HypA	NA	NA	NA	NA
WP_152381705.1\|5067205_5067868_+	hydrogenase nickel incorporation protein HypB	NA	NA	NA	NA
WP_152381706.1\|5067885_5068164_+	twin-arginine translocase TatA/TatE family subunit	NA	NA	NA	NA
WP_152381707.1\|5068185_5068935_+	Sec-independent protein secretion pathway component TatC	NA	NA	NA	NA
WP_152381708.1\|5068927_5069671_+	twin-arginine translocase subunit TatC	NA	NA	NA	NA
WP_152381709.1\|5069701_5072065_+	carbamoyltransferase HypF	NA	NA	NA	NA
WP_152381710.1\|5072037_5072262_+	HypC/HybG/HupF family hydrogenase formation chaperone	NA	NA	NA	NA
WP_152382252.1\|5072257_5073340_+	hydrogenase formation protein HypD	NA	NA	NA	NA
WP_152381711.1\|5073354_5074365_+	hydrogenase expression/formation protein HypE	NA	NA	NA	NA
WP_152381712.1\|5074493_5075498_+	hypothetical protein	NA	NA	NA	NA
WP_152381713.1\|5076129_5076303_+	recombinase family protein	NA	NA	NA	NA
5076299:5076314	attL	NA	NA	NA	NA
WP_167518764.1\|5076778_5077336_-\|integrase	tyrosine-type recombinase/integrase	A0A1B1IQT7	uncultured_Mediterranean_phage	4.6e-05	27.6
WP_152381674.1\|5077365_5077698_-\|transposase	transposase	NA	NA	NA	NA
WP_152381715.1\|5077835_5078681_-	hypothetical protein	NA	NA	NA	NA
WP_152381716.1\|5078696_5079458_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_152381717.1\|5079571_5079943_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_152382253.1\|5080352_5080925_+	recombinase family protein	A0A219YB42	Aeromonas_phage	1.9e-25	40.2
WP_152381718.1\|5081501_5082095_-	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	5.6e-25	38.7
WP_152382254.1\|5082406_5082988_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_152381719.1\|5083316_5083976_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_152381720.1\|5084024_5084669_+	NAD(P)H-binding protein	NA	NA	NA	NA
WP_152382255.1\|5085851_5086565_+	thioredoxin domain-containing protein	NA	NA	NA	NA
WP_152382256.1\|5087503_5088421_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_152379390.1\|5088697_5089918_+\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	7.7e-53	32.1
WP_152381721.1\|5090370_5090952_+	TetR family transcriptional regulator	NA	NA	NA	NA
WP_152381722.1\|5091014_5091857_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_167518765.1\|5093343_5093517_+	hypothetical protein	NA	NA	NA	NA
WP_167518766.1\|5093579_5093729_-	hypothetical protein	NA	NA	NA	NA
WP_152381723.1\|5094090_5094477_+	hypothetical protein	NA	NA	NA	NA
WP_152382257.1\|5094476_5094812_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_152381724.1\|5094860_5095283_+	hypothetical protein	NA	NA	NA	NA
WP_152381725.1\|5095671_5096742_+	tyrosine recombinase XerS	S5M9V8	Brevibacillus_phage	1.4e-05	22.1
WP_167518767.1\|5097226_5097478_-	hypothetical protein	NA	NA	NA	NA
5096896:5096911	attR	NA	NA	NA	NA
WP_167518768.1\|5097877_5098072_-	hypothetical protein	NA	NA	NA	NA
WP_167518769.1\|5098052_5098226_-	hypothetical protein	NA	NA	NA	NA
WP_152380265.1\|5098555_5099319_-\|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	1.3e-37	59.8
WP_152381726.1\|5100375_5101368_+	amidohydrolase family protein	NA	NA	NA	NA
WP_167518770.1\|5101688_5101859_-\|transposase	IS110 family transposase	NA	NA	NA	NA

DBSCAN-SWA_14

5140782 : 5157938

Tupanvirus(28.57%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_007432418.1\|5140782_5141034_-	hypothetical protein	A0A0C5ABD9	Paenibacillus_phage	1.4e-17	59.5
WP_152381741.1\|5141222_5141792_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_152381742.1\|5141918_5143391_+	DHA2 family efflux MFS transporter permease subunit	A0A0M3UL24	Mycobacterium_phage	5.1e-11	24.7
WP_152381743.1\|5143576_5145034_-	catalase	A0A2K9L0T1	Tupanvirus	4.9e-115	43.0
WP_152381744.1\|5145243_5145846_-	adenylyl-sulfate kinase	NA	NA	NA	NA
WP_152381745.1\|5145922_5146825_-	TIGR02452 family protein	G3MBH6	Bacillus_virus	2.3e-54	43.8
WP_152381746.1\|5146821_5147313_-	DUF1768 domain-containing protein	A0A0S0N9W6	Pseudomonas_phage	4.9e-43	56.8
WP_152381747.1\|5147337_5148243_-	NUDIX domain-containing protein	G3MA14	Bacillus_virus	5.9e-34	33.9
WP_152381748.1\|5148468_5149350_-	hypothetical protein	NA	NA	NA	NA
WP_152382260.1\|5149346_5157938_-	amino acid adenylation domain-containing protein	A0A2K9KZV5	Tupanvirus	5.3e-116	21.7

DBSCAN-SWA_15

5335270 : 5390110

Paenibacillus_phage(22.86%)

head,capsid,integrase,transposase,terminase,tail,holin

attL 5383989:5384003|attR 5396331:5396345

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_152381862.1\|5335270_5335831_-	hypothetical protein	D0R7H9	Paenibacillus_phage	9.5e-67	79.8
WP_152381863.1\|5335833_5336610_-	M15 family peptidase	U5PWQ2	Bacillus_phage	1.1e-36	52.3
WP_152381864.1\|5336566_5337055_-\|holin	holin	D9ZNF2	Clostridium_phage	4.2e-18	38.8
WP_152381865.1\|5337076_5337298_-	hypothetical protein	NA	NA	NA	NA
WP_152382266.1\|5337337_5338015_-	hypothetical protein	A0A2D1GQ65	Lysinibacillus_phage	2.9e-54	51.2
WP_152381866.1\|5339313_5339898_-	2,' 3'-cyclic nucleotide 2'-phosphodiesterase	R9TPZ8	Paenibacillus_phage	3.4e-14	34.3
WP_152381867.1\|5339962_5342113_-	hypothetical protein	A0A2H4JAC2	uncultured_Caudovirales_phage	3.2e-17	26.9
WP_152381868.1\|5342125_5342755_-	hypothetical protein	NA	NA	NA	NA
WP_152381869.1\|5342788_5342929_-	XkdX family protein	A0A0A7RTH5	Clostridium_phage	9.7e-13	71.1
WP_152381870.1\|5342925_5343390_-	hypothetical protein	NA	NA	NA	NA
WP_025717934.1\|5345745_5346156_-	hypothetical protein	H6BJ44	Methylophilales_phage	4.3e-24	41.6
WP_152381871.1\|5346168_5346723_-\|tail	phage tail protein	NA	NA	NA	NA
WP_152381872.1\|5346723_5352138_-	transglycosylase	NA	NA	NA	NA
WP_167518779.1\|5352238_5352382_-	hypothetical protein	NA	NA	NA	NA
WP_152381873.1\|5352524_5352863_-	hypothetical protein	NA	NA	NA	NA
WP_025717263.1\|5352927_5353716_-	hypothetical protein	NA	NA	NA	NA
WP_152381874.1\|5353760_5353973_-	hypothetical protein	NA	NA	NA	NA
WP_152381875.1\|5353983_5354418_-	hypothetical protein	NA	NA	NA	NA
WP_152381876.1\|5354414_5354993_-	hypothetical protein	NA	NA	NA	NA
WP_152381877.1\|5354989_5355565_-	hypothetical protein	NA	NA	NA	NA
WP_152381878.1\|5355564_5355999_-	hypothetical protein	NA	NA	NA	NA
WP_152381879.1\|5355988_5356378_-	hypothetical protein	NA	NA	NA	NA
WP_152381880.1\|5356395_5357409_-\|capsid	major capsid protein E	A0A1U9WQS4	Geobacillus_phage	8.4e-13	23.4
WP_090738476.1\|5357424_5357805_-\|head	head decoration protein	A0A139ZPE9	Marinitoga_camini_virus	1.6e-09	47.1
WP_152381881.1\|5357807_5359112_-	hypothetical protein	NA	NA	NA	NA
WP_152381882.1\|5359116_5360577_-	hypothetical protein	A0A0K2CP66	Brevibacillus_phage	8.3e-54	32.1
WP_152381883.1\|5360782_5361250_-	hypothetical protein	NA	NA	NA	NA
WP_152381884.1\|5361264_5361720_-	hypothetical protein	NA	NA	NA	NA
WP_152381885.1\|5361855_5362203_-	hypothetical protein	NA	NA	NA	NA
WP_152381886.1\|5362886_5363288_-	SnoaL-like domain-containing protein	NA	NA	NA	NA
WP_152381887.1\|5363695_5364313_-	DUF4367 domain-containing protein	NA	NA	NA	NA
WP_167518780.1\|5364328_5364820_-	hypothetical protein	NA	NA	NA	NA
WP_167518781.1\|5365177_5365396_+	hypothetical protein	NA	NA	NA	NA
WP_152381889.1\|5365384_5365594_-	hypothetical protein	NA	NA	NA	NA
WP_152381890.1\|5365818_5367276_-\|terminase	terminase B	A0A0A8WEW2	Clostridium_phage	1.1e-151	59.0
WP_152381891.1\|5367211_5368501_-	cell division protein FtsK	M4ZS05	Bacillus_phage	3.4e-35	50.0
WP_167518782.1\|5368593_5369079_-	hypothetical protein	NA	NA	NA	NA
WP_152381893.1\|5369213_5369414_-	hypothetical protein	NA	NA	NA	NA
WP_152382267.1\|5369410_5369704_-	DUF2829 domain-containing protein	I6X2Q9	Vibriophage	2.0e-36	73.7
WP_152381894.1\|5369816_5370770_-	glycosyl hydrolase	NA	NA	NA	NA
WP_152381895.1\|5371106_5371361_-	hypothetical protein	NA	NA	NA	NA
WP_069289728.1\|5371493_5372132_-	hypothetical protein	NA	NA	NA	NA
WP_152381896.1\|5372256_5372646_-	hypothetical protein	NA	NA	NA	NA
WP_152381897.1\|5372642_5372873_-	hypothetical protein	NA	NA	NA	NA
WP_167518783.1\|5372875_5373046_-	hypothetical protein	NA	NA	NA	NA
WP_152381898.1\|5373087_5373429_-	hypothetical protein	NA	NA	NA	NA
WP_152381899.1\|5373471_5373861_-	hypothetical protein	A0A0A0RVG0	Bacillus_phage	4.1e-08	52.5
WP_167518784.1\|5373853_5374087_-	hypothetical protein	A0A0C5AJ91	Bacteriophage	1.9e-05	45.0
WP_152380825.1\|5374130_5374316_-	hypothetical protein	S5MP11	Brevibacillus_phage	8.9e-14	60.7
WP_152381901.1\|5374361_5374868_-	hypothetical protein	S4S2L7	Puniceispirillum_phage	1.9e-10	33.1
WP_152381902.1\|5374933_5375794_-	DNA (cytosine-5-)-methyltransferase	Q7Y4B5	Escherichia_virus	1.6e-12	26.6
WP_152381903.1\|5375825_5376023_-	hypothetical protein	NA	NA	NA	NA
WP_152381904.1\|5376247_5376919_-	HNH endonuclease	D0R7I8	Paenibacillus_phage	2.9e-62	68.2
WP_152381905.1\|5377002_5377185_-	hypothetical protein	NA	NA	NA	NA
WP_152381906.1\|5377181_5377370_-	hypothetical protein	NA	NA	NA	NA
WP_152381907.1\|5377441_5377765_-	hypothetical protein	NA	NA	NA	NA
WP_167518785.1\|5377827_5377989_-	hypothetical protein	NA	NA	NA	NA
WP_152378784.1\|5378234_5379352_-\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	2.6e-116	72.8
WP_152381908.1\|5379696_5379921_+	helix-turn-helix domain-containing protein	A0A2I6UHW7	Bacillus_phage	1.9e-10	51.5
WP_152381909.1\|5379947_5380175_-	hypothetical protein	D0R7I6	Paenibacillus_phage	1.8e-32	94.7
WP_152382268.1\|5380171_5380468_-	hypothetical protein	A0A218KCM5	Bacillus_phage	3.9e-11	47.9
WP_152381910.1\|5380436_5380955_-	DUF1064 domain-containing protein	D0R7I5	Paenibacillus_phage	6.8e-67	75.0
WP_152381911.1\|5380951_5382085_-	DNA polymerase III subunit beta	D0R7I4	Paenibacillus_phage	4.0e-80	93.9
WP_152381912.1\|5382201_5383152_-	primosomal protein DnaI	S5MU12	Brevibacillus_phage	1.8e-65	50.0
WP_152381913.1\|5383158_5384172_-	hypothetical protein	E8ZDM9	Streptococcus_phage	1.3e-42	52.8
5383989:5384003	attL	NA	NA	NA	NA
WP_128574146.1\|5384206_5384605_-	hypothetical protein	A0A0K2CYI4	Paenibacillus_phage	2.1e-07	35.4
WP_152381914.1\|5384675_5385071_-	hypothetical protein	NA	NA	NA	NA
WP_152381915.1\|5385061_5385430_-	hypothetical protein	NA	NA	NA	NA
WP_152381916.1\|5385540_5385972_-	ABC transporter permease	A0A2P0VGQ9	Streptococcus_phage	1.3e-07	25.2
WP_152381917.1\|5385952_5387092_-	ParB N-terminal domain-containing protein	A0A1D6Z271	Staphylococcus_phage	6.5e-46	50.5
WP_167518786.1\|5387179_5387431_+	hypothetical protein	A0A0A7RTK6	Clostridium_phage	3.4e-16	50.0
WP_152381919.1\|5387432_5387654_-	hypothetical protein	NA	NA	NA	NA
WP_152381920.1\|5387667_5387934_-	group-specific protein	A0A1B1P7U4	Bacillus_phage	6.2e-24	55.8
WP_152381921.1\|5387957_5388173_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_152381922.1\|5388350_5388956_+	helix-turn-helix domain-containing protein	E5DV74	Deep-sea_thermophilic_phage	2.0e-41	45.0
WP_152381923.1\|5388967_5390110_+\|integrase	tyrosine-type recombinase/integrase	A0A0S2SXP1	Bacillus_phage	1.1e-58	61.7
5396331:5396345	attR	NA	NA	NA	NA

DBSCAN-SWA_16

5573319 : 5580439

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_152382038.1\|5573319_5574582_-	D-alanyl-D-alanine carboxypeptidase	A0A1P8VVG5	Erythrobacter_phage	6.6e-07	30.7
WP_152382039.1\|5574778_5575501_+	protein-glutamine gamma-glutamyltransferase	NA	NA	NA	NA
WP_025721026.1\|5575584_5576073_-	sporulation protein YtfJ	NA	NA	NA	NA
WP_152382040.1\|5576157_5576859_-	DUF2953 domain-containing protein	NA	NA	NA	NA
WP_152382041.1\|5576992_5577601_-	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	4.1e-15	32.8
WP_025721032.1\|5577569_5578364_-	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	3.7e-08	30.5
WP_025721033.1\|5578536_5579001_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	5.2e-42	59.9
WP_152382042.1\|5579030_5579714_-	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	2.2e-57	54.7
WP_025721037.1\|5579773_5580439_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	3.4e-39	40.5

Anti-CRISPR protein detection

Acr_ID: NZ_CP045298.1|WP_152380721.1|3496878_3497847_+|hypothetical-protein

Click the colored protein region to show detailed information

Acr_ID: NZ_CP045298.1|WP_167518720.1|3667295_3667532_+|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_CP045298.1|WP_152380721.1|3496878_3497847_+|hypothetical-protein

3496878_3497847_+

322 aa aa

HTH_XRE

Identity	Hit_domain_coverage
0.4827586206896552	0.9827586206896551

3415240-3512083

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP045298_1	Orphan	1.22\|1866319\|35\|NZ_CP045298\|CRISPRCasFinder,CRT,PILER-CR	1866319-1866353	35	3477000-3476966	0
NZ_CP045298_7	orTypeI	7.1\|4517767\|35\|NZ_CP045298\|PILER-CR,CRISPRCasFinder,CRT	4517767-4517801	35	3476103-3476137	0

1. spacer 1.22|1866319|35|NZ_CP045298|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP045298 position: 3477000-3476966, mismatch: 0

cgattcatcacgaaagagtagacgacaatcagaat	CRISPR spacer
cgattcatcacgaaagagtagacgacaatcagaat	Protospacer
***********************************

2. spacer 7.1|4517767|35|NZ_CP045298|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045298 position: 3476103-3476137, mismatch: 0

atccgagctgccagaggtactgggcttgtgtgacc	CRISPR spacer
atccgagctgccagaggtactgggcttgtgtgacc	Protospacer
***********************************

NZ_CP045298.1|WP_167518720.1|3667295_3667532_+|hypothetical-protein

3667295_3667532_+

78 aa aa

HTH_21,HTH_ARAC

Identity	Hit_domain_coverage
0.4230769230769231	0.864406779661017

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP045298

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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