CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP045353	Vibrio sp. THAF100 plasmid pTHAF100_c, complete sequence	0 crisprs	NA	0	0
NZ_CP045352	Vibrio sp. THAF100 plasmid pTHAF100_b, complete sequence	0 crisprs	NA	0	2
NZ_CP045351	Vibrio sp. THAF100 plasmid pTHAF100_a, complete sequence	1 crisprs	DEDDh,RT,cas3,csa3,WYL	2	0
NZ_CP045350	Vibrio sp. THAF100 chromosome, complete genome	1 crisprs	DEDDh,TnsE_C,csa3,cas3,cas5,cas8c,cas7,cas4,cas1,cas2,DinG,csx1	5	4

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1108 : 10261

Vibrio_phage(33.33%)

tail

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_152432800.1\|1108_1645_+	hypothetical protein	A0A1V0E872	Vibrio_phage	3.0e-17	41.0
WP_152432801.1\|1712_1910_+	hypothetical protein	NA	NA	NA	NA
WP_152432802.1\|1912_3079_+	hypothetical protein	Q6R4W2	Vibrio_virus	1.7e-54	32.9
WP_152432803.1\|3078_3555_+\|tail	phage major tail tube protein	NA	NA	NA	NA
WP_152432804.1\|3715_4273_+	hypothetical protein	NA	NA	NA	NA
WP_152432805.1\|4397_6851_+\|tail	phage tail tape measure protein	A0A0R6PIE5	Moraxella_phage	1.7e-14	25.1
WP_152432806.1\|6854_7250_+\|tail	phage tail protein	NA	NA	NA	NA
WP_152432807.1\|7224_7434_+	hypothetical protein	NA	NA	NA	NA
WP_152432808.1\|7424_8384_+	hypothetical protein	A2I2Y5	Vibrio_virus	1.5e-43	31.9
WP_152432809.1\|8387_8936_+	N-acetylmuramoyl-L-alanine amidase	A0A2I7RHK5	Vibrio_phage	2.5e-51	56.6
WP_152432810.1\|8925_9105_+	hypothetical protein	NA	NA	NA	NA
WP_152432811.1\|9101_9659_+	hypothetical protein	NA	NA	NA	NA
WP_152432812.1\|9679_10261_-	recombinase family protein	Q2A092	Sodalis_phage	7.4e-38	48.9

DBSCAN-SWA_2

28935 : 39476

Vibrio_virus(37.5%)

protease,terminase,tail,plate,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_152432852.1\|28935_31038_+\|terminase	phage terminase large subunit family protein	A0A219YAX2	Aeromonas_phage	7.5e-72	31.9
WP_152432853.1\|31027_31273_+	hypothetical protein	NA	NA	NA	NA
WP_152432854.1\|31269_32781_+\|portal	phage portal protein	S5MW34	Escherichia_phage	1.3e-41	28.3
WP_172971896.1\|32719_34849_+\|protease	ATP-dependent Clp protease proteolytic subunit	A0A1W6JT88	Pseudomonas_phage	2.8e-26	25.5
WP_152432857.1\|34913_35237_+	DUF2190 family protein	A0A2I7QRW1	Vibrio_phage	4.4e-08	40.2
WP_152432858.1\|35176_35518_+	hypothetical protein	NA	NA	NA	NA
WP_152432859.1\|35557_36076_+	hypothetical protein	NA	NA	NA	NA
WP_152432860.1\|36050_36542_+	hypothetical protein	NA	NA	NA	NA
WP_152432861.1\|36544_37270_+\|plate	phage baseplate assembly protein V	A2I2X5	Vibrio_virus	5.1e-12	38.4
WP_152432862.1\|37284_37491_+	hypothetical protein	NA	NA	NA	NA
WP_152432863.1\|37586_37913_+	hypothetical protein	A2I2X7	Vibrio_virus	9.6e-11	35.5
WP_152432864.1\|37909_38887_+\|plate	baseplate J/gp47 family protein	A0A1I9KG27	Aeromonas_phage	1.1e-33	31.2
WP_172971897.1\|38876_39476_+\|tail	phage tail protein I	Q6R4V7	Vibrio_virus	3.4e-14	33.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP045351

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP045351_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045351_1

362338-362520

Orphan

Consensus_repeat	Method
TGAGAAGTATTCCAATAGCCGATGTCTTGATTAAA	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP045351_1

>merge|NZ_CP045351|1|362338-362520|PILER-CR
TGAGGTATTCCAACGGCCAATGTCTTGATTAAAGTTCTCTGCTCCACCAAACATCGAATGCATCCATTTCACGTGAGATGTATTCCAGTAGCCGATGTCTTGATTAAACTTTTTGGCTCTAAAAAACATCCAAGCCATACTAACCACTTTAGAAGTATCCCAATAGCCGATGTCTTGATTAAA

>NZ_CP045351|1|1|362338-362520|PILER-CR
TGAGGTATTCCAACGGCCAATGTCTTGATTAAAGT	TCTCTGCTCCACCAAACATCGAATGCATCCATTTCACGTG
AGATGTATTCCAGTAGCCGATGTCTTGATTAAACT	TTTTGGCTCTAAAAAACATCCAAGCCATACTAACCACTTT
AGAAGTATCCCAATAGCCGATGTCTTGATTAAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045351.1\|WP_152432023.1\|354668_355079_-\|NUDIX-domain-containing-protein	unknown	unknown	gnl\|CDD\|239217
NZ_CP045351.1\|WP_152432033.1\|366632_367472_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045351.1\|WP_152432028.1\|359201_360317_-\|BspA-family-leucine-rich-repeat-surface-protein	unknown	unknown	gnl\|CDD\|308794
NZ_CP045351.1\|WP_114786344.1\|352694_353312_-\|OmpA-family-protein	unknown	unknown	gnl\|CDD\|143586
NZ_CP045351.1\|WP_152432026.1\|357396_358437_-\|BspA-family-leucine-rich-repeat-surface-protein	unknown	unknown	gnl\|CDD\|308794
NZ_CP045351.1\|WP_152432756.1\|371022_373380_+\|fatty-acid-cis/trans-isomerase	unknown	unknown	gnl\|CDD\|369142
NZ_CP045351.1\|WP_152432024.1\|355300_355921_-\|ATP-dependent-zinc-protease	unknown	unknown	gnl\|CDD\|226553
NZ_CP045351.1\|WP_152432032.1\|364635_366531_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|223715
NZ_CP045351.1\|WP_152432037.1\|375044_376637_-\|dipeptide-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226641
NZ_CP045351.1\|WP_114786331.1\|373419_373608_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045351.1\|WP_152432021.1\|353496_354114_+\|thioredoxin-domain-containing-protein	unknown	unknown	gnl\|CDD\|239317
NZ_CP045351.1\|WP_152432755.1\|367873_369166_-\|diguanylate-cyclase	unknown	unknown	gnl\|CDD\|270424
NZ_CP045351.1\|WP_152432031.1\|363713_364568_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045351.1\|WP_152432034.1\|369602_370835_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340911
NZ_CP045351.1\|WP_152432027.1\|358475_358913_-\|BspA-family-leucine-rich-repeat-surface-protein	unknown	unknown	gnl\|CDD\|308794
NZ_CP045351.1\|WP_152432036.1\|374207_375005_+\|transporter-substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|270422
NZ_CP045351.1\|WP_152432022.1\|354132_354606_+\|FKBP-type-peptidyl-prolyl-cis-trans-isomerase	unknown	unknown	gnl\|CDD\|223619
NZ_CP045351.1\|WP_152432035.1\|373689_374106_-\|RNA-binding-S4-domain-containing-protein	unknown	unknown	gnl\|CDD\|379097
NZ_CP045351.1\|WP_152432025.1\|355992_357174_-\|aromatic-amino-acid-transaminase	unknown	unknown	gnl\|CDD\|181731
NZ_CP045351.1\|WP_152432029.1\|360618_361737_-\|BspA-family-leucine-rich-repeat-surface-protein	unknown	unknown	gnl\|CDD\|308794

Protein	Function_ID	Function_description	E-value
NZ_CP045351.1\|WP_152432023.1\|354668_355079_-\|NUDIX-domain-containing-protein	gnl\|CDD\|239217	cd02883, Nudix_Hydrolase, Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ for their activity. Members of this family are recognized by a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which forms a structural motif that functions as a metal binding and catalytic site. Substrates of nudix hydrolase include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance and "house-cleaning" enzymes. Substrate specificity is used to define child families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required. This superfamily consists of at least nine families: IPP (isopentenyl diphosphate) isomerase, ADP ribose pyrophosphatase, mutT pyrophosphohydrolase, coenzyme-A pyrophosphatase, MTH1-7,8-dihydro-8-oxoguanine-triphosphatase, diadenosine tetraphosphate hydrolase, NADH pyrophosphatase, GDP-mannose hydrolase and the c-terminal portion of the mutY adenine glycosylase.	2.60328e-13
NZ_CP045351.1\|WP_152432035.1\|373689_374106_-\|RNA-binding-S4-domain-containing-protein	gnl\|CDD\|379097	pfam13275, S4_2, S4 domain. The S4 domain is a small domain consisting of 60-65 amino acid residues that was detected in the bacterial ribosomal protein S4.	6.13186e-23
NZ_CP045351.1\|WP_152432028.1\|359201_360317_-\|BspA-family-leucine-rich-repeat-surface-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	5.17819e-52
NZ_CP045351.1\|WP_114786344.1\|352694_353312_-\|OmpA-family-protein	gnl\|CDD\|143586	cd07185, OmpA_C-like, Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA. OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.	2.28636e-36
NZ_CP045351.1\|WP_152432026.1\|357396_358437_-\|BspA-family-leucine-rich-repeat-surface-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	3.05069e-54
NZ_CP045351.1\|WP_152432756.1\|371022_373380_+\|fatty-acid-cis/trans-isomerase	gnl\|CDD\|369142	pfam06934, CTI, Fatty acid cis/trans isomerase (CTI). This family consists of several fatty acid cis/trans isomerase proteins which appear to be found exclusively in bacteria of the orders Vibrionales and Pseudomonadales. Cis/trans isomerase (CTI) catalyzes the cis-trans isomerisation of esterified fatty acids in phospholipids, mainly cis-oleic acid (C(16:1,9)) and cis-vaccenic acid (C(18:1,11)), in response to solvents. The CTI protein has been shown to be involved in solvent resistance in Pseudomonas putida.	0
NZ_CP045351.1\|WP_152432024.1\|355300_355921_-\|ATP-dependent-zinc-protease	gnl\|CDD\|226553	COG4067, COG4067, Uncharacterized protein conserved in archaea [Posttranslational modification, protein turnover, chaperones].	7.77951e-57
NZ_CP045351.1\|WP_152432032.1\|364635_366531_-\|ATP-binding-protein	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.06979e-31
NZ_CP045351.1\|WP_152432037.1\|375044_376637_-\|dipeptide-ABC-transporter-ATP-binding-protein	gnl\|CDD\|226641	COG4172, COG4172, ABC-type uncharacterized transport system, duplicated ATPase component [General function prediction only].	0
NZ_CP045351.1\|WP_152432036.1\|374207_375005_+\|transporter-substrate-binding-domain-containing-protein	gnl\|CDD\|270422	cd13704, PBP2_HisK, The periplasmic sensor domain of histidine kinase receptors; the type 2 periplasmic binding fold protein. This subfamily includes the periplasmic sensor domain of the histidine kinase receptors (HisK) which are elements of the two-component signal transduction systems commonly found in bacteria and lower eukaryotes. Typically, the two-component system consists of a membrane-spanning histidine kinase sensor and a cytoplasmic response regulator. The two-component systems serve as a stimulus-response coupling mechanism to enable microorganisms to sense and respond to changes in environmental conditions. Extracellular stimuli such as small molecule ligands and ions are detected by the N-terminal periplasmic sensing domain of the sensor kinase receptor, which regulate the catalytic activity of the cytoplasmic kinase domain and promote ATP-dependent autophosphorylation of a conserved histidine residue. The phosphate is then transferred to a conserved aspartate in the response regulator through a phospho-transfer mechanism, and the activity of the response regulator is in turn regulated. The sensor domain belongs to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space through their function as an initial high-affinity binding component. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.48624e-15
NZ_CP045351.1\|WP_152432021.1\|353496_354114_+\|thioredoxin-domain-containing-protein	gnl\|CDD\|239317	cd03019, DsbA_DsbA, DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol oxidant known, due to the unusual stability of the thiolate anion form of the first cysteine in the CXXC motif. The highly unstable oxidized form of DsbA directly donates disulfide bonds to reduced proteins secreted into the bacterial periplasm. This rapid and unidirectional process helps to catalyze the folding of newly-synthesized polypeptides. To regain catalytic activity, reduced DsbA is then reoxidized by the membrane protein DsbB, which generates its disulfides from oxidized quinones, which in turn are reoxidized by the electron transport chain.	1.26547e-36
NZ_CP045351.1\|WP_152432755.1\|367873_369166_-\|diguanylate-cyclase	gnl\|CDD\|270424	cd13706, PBP2_HisK_like_1, Putative sensor domain similar to HisK; the type 2 periplasmic binding fold protein. This group includes periplasmic sensor domain of the histidine kinase receptors (HisK) which are elements of the two-component signal transduction systems commonly found in bacteria and lower eukaryotes. Typically, the two-component system consists of a membrane-spanning histidine kinase sensor and a cytoplasmic response regulator. The two-component systems serve as a stimulus-response coupling mechanism to enable microorganisms to sense and respond to changes in environmental conditions. Extracellular stimuli such as small molecule ligands and ions are detected by the N-terminal periplasmic sensing domain of the sensor kinase receptor, which regulate the catalytic activity of the cytoplasmic kinase domain and promote ATP-dependent autophosphorylation of a conserved histidine residue. The phosphate is then transferred to a conserved aspartate in the response regulator through a phospho-transfer mechanism, and the activity of the response regulator is in turn regulated. The sensor domain belongs to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space through their function as an initial high-affinity binding component. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	4.70831e-95
NZ_CP045351.1\|WP_152432034.1\|369602_370835_+\|MFS-transporter	gnl\|CDD\|340911	cd17353, MFS_OFA_like, Oxalate:formate antiporter (OFA) and similar proteins of the Major Facilitator Superfamily of transporters. This subfamily is composed of Oxalobacter formigenes oxalate:formate antiporter (OFA or OxlT) and similar proteins. O. formigenes, a commensal found in the gut of animals and humans, plays an important role in clearing dietary oxalate from the intestinal tract, which is carried out by OFA/OxlT, an anion transporter that facilitates the exchange of divalent oxalate with monovalent formate, the product of oxalate decarboxylation. This exchange generates an electrochemical proton gradient and is the source of energy for ATP synthesis in this cell. The OFA-like subfamily belongs to the Monocarboxylate transporter -like (MCT-like) family of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.39084e-101
NZ_CP045351.1\|WP_152432027.1\|358475_358913_-\|BspA-family-leucine-rich-repeat-surface-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	1.55253e-25
NZ_CP045351.1\|WP_152432022.1\|354132_354606_+\|FKBP-type-peptidyl-prolyl-cis-trans-isomerase	gnl\|CDD\|223619	COG0545, FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones].	2.49561e-61
NZ_CP045351.1\|WP_152432025.1\|355992_357174_-\|aromatic-amino-acid-transaminase	gnl\|CDD\|181731	PRK09257, PRK09257, aromatic amino acid transaminase.	0
NZ_CP045351.1\|WP_152432029.1\|360618_361737_-\|BspA-family-leucine-rich-repeat-surface-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	5.30323e-51

>NZ_CP045351.1|WP_152432029.1|360618_361737_-|BspA-family-leucine-rich-repeat-surface-protein
MKNTYALLALGSFLVLGHQAHASEISVKCSNDAVNSIIIKGGIEYLVVDNELIKNRYRLYDLEQGKIRFCTTHVTSMYSVFSSSKKFNADISDWDTSNVTDMGMMFSQALAFNQDIGNWDTSKVTSMAGMFASAESFNQNISHWNTSSVSDMSMMFSNAKSFNQNLGRWDTSNVTDMSDMFNWAESFDQDIGDWDTSNVELMSGMFSSARSFNQEIGSWDTSKVVSMSSMFGDTRAFNQNIGDWNTSNVTNMMAMFSGATAFNQDIGNWNTSKVTDVQFMFSGAQAFNQYIGLWDMSNATNMIGMFMDAIEFNQNISPWDTSNVKYMAHIFEGASSFSQNLTNWNVNNVEWHENYRKGSRLYNNKVPYSFRY
>NZ_CP045351.1|WP_152432028.1|359201_360317_-|BspA-family-leucine-rich-repeat-surface-protein
MIKKITSILAGSFVLASQCVFAIDISVKCPDQPINSVLIEKGQVYVVVDNALIRNQTMLDKLEKGHIGFCTTQVTNMDMVFFEKASFNADISDWDTSNVTSMHSMFLYAEAFNQDIGFWDTSNVATMLQMFSFAKAFNQDIGHWDTASVTEMQSMFHKAQAFNQDIGHWDTSKVTNMFGMFYQADAFNKNISHWDTANVTNMNNMFQGADVFNANIGSWDTSKVTTMDYMFNGAEAFNQDIGHWNTSQVTSMQGMFMVAYRFNQDIGHWDMSKVTNINRMFLGGYAFNQDIGHWDTSKVTDMSGTFNAALLFNQDIGHWDTSNVVNMKEMFSQATRFSQDLSNWNVSQVTEHNDFAKDSILTEQQLPIFTQ
>NZ_CP045351.1|WP_152432027.1|358475_358913_-|BspA-family-leucine-rich-repeat-surface-protein
MKLTSVILACMALGSAASFAEEDHIIRCDANPPGSVVIINERLYVVVDNALLRQEDYWQNFIHGKIELCTSHVTDMSDLFAQSPYFNYDISQWDTRRVTNMDRMFKGAKRFNQDLSNWSVEKVTRHQDFALQSGLPDYYLPQFQH
>NZ_CP045351.1|WP_152432026.1|357396_358437_-|BspA-family-leucine-rich-repeat-surface-protein
MKKNLLSLLVGAAALASQQAYAIDISVKCPDQPVNSVLMENGKVYIVVDNDLIRNQTLLDNLEQGHIGFCTTQVTNMDGVFSKRSTFNVDISDWDTSNVTSMHEMFTHAKAFNQDIGHWDTSKVTTMQRMFAGAYAFNQGIGHWDTSNVTSMNFMFNGADAFNQDIGHWDTSNVTNMWGMFYGADAFNQDIGYWDTSNVTYMGAMFYGTDTFNQGIGQWDTSNVTDMRDMFYLAKAFNQDIGQWDTFNVINMGRMFSYAVAFNQAIGHWDTSNVTDMRSMFYLAKAFNQDIGFWDTSNVTNMKEMFKGNATFSQDLSNWNVSQVTEHTDFAKDSVLTEEQLPIFIQ
>NZ_CP045351.1|WP_152432025.1|355992_357174_-|aromatic-amino-acid-transaminase
MFSHLPTPVLDPILSLSVAYRNDPRPDKVDLGIGVYKNSAGETPVMKAISQAQDIVVASQKTKSYVGLAGCEEFNQSMVELLLSGTSAMERVAAIQTPGASGALRMLGDLIKVAQPDTCVWLSNPSYVNHRPVMEAAGLKVKQYTYFSPQTKQVDTSRMLEELVHAGPNDVVLLHGCCHNPTGADIDFTTWQAITELAQKNGFVPFVDVAYQGFGDGLEQDVQGLRFMADNVEEMMITTSCSKNFGLYRERTGAAIVVGKSLQEVTNAKGRALTLARSTYTMPPDHGAALVKTILQSHELTGIWKQELSEMQQRLVSLRKSLCQEFQNTHNTSQFDFIENHKGMFTMLGFSQEQMAQLRETYGIYGVGDGRINIAGLTEKDMAYVADAIVKVC
>NZ_CP045351.1|WP_152432024.1|355300_355921_-|ATP-dependent-zinc-protease
MDRTSKALIAMLLSGGLMACSTTSQKPEEPQPKPAIEEPKDNPESPEAEKDKQTAEKPKPQPKKTADGKLILGQQEWVYVPGLEENFKARIDTGATTSSISATDVVEFERDGQDWVKFTIEHDGKKSKQMALPVVRWVKVRQSSSEESQRRAVVESWVQLGDLKEKTEFTLADRTHLNYPLLLGRSFVTDVAIVDVSKEFVQKKYK
>NZ_CP045351.1|WP_152432023.1|354668_355079_-|NUDIX-domain-containing-protein
MKYLSMAVVIKHGKVLIQERYRSNQGMVFEFPGGEVETNESGTDAAIRELYEETNMSGLSHVATYSDINEYGGRIYYVVLHASHHDEPRANDSSRQQTFHWLCLDNLPIDEFYKADVSFIRQHLAKHLQREVGEMA
>NZ_CP045351.1|WP_152432022.1|354132_354606_+|FKBP-type-peptidyl-prolyl-cis-trans-isomerase
MSKIIIPIVILVLAGFMIYRTLVTSKAGEENFAAGQAFLLENGKQEGVITTESGLQYKVLSKGEGTTNPSPKSKVKVHYHGTLIDGTVFDSSVERGEPISFGLNQVIKGWQEGLTYMVEGDKFRLFIPSTLAYGKKGTGPIPPASTLIFDVELLEIQ
>NZ_CP045351.1|WP_152432021.1|353496_354114_+|thioredoxin-domain-containing-protein
MRKILAFAGLILVALLAGCSKSEHPQEGKQFERLPTDLSAYQLPVVTEVFSLNCGHCANMESAIPQLEAATNQTFGKVHVIFNQSAQVSAMIYYSAQTQLGTTPSHDLMNAMFNAVQMEGATAQQQKQAINKAFTDQDLSSPDKLTEDQRRTLFAAMQQAAEISQKGQINAVPTFIVNGKYMVLLAGHKDLDGIANTINYLIQQP
>NZ_CP045351.1|WP_114786344.1|352694_353312_-|OmpA-family-protein
MKYLALPLLLLLTGCGNLAKEMRYMTDDMLETAPKTDMDVRYPSWGNAPRVASRSGVMGPMGREASYSDLQSFLMKNGVEHEVLPGDHLMVKLTDTIKFNTGSSMVEPSSAYWLNKMGSYLATQPGIDIVIDGHTDNTGPPSRNDVLSMKRAKAVKQQLIRNNVAMDAIFTRGYGEYVPACTNSTRAGKACNRRVEVLFIVANQR
>NZ_CP045351.1|WP_152432031.1|363713_364568_-|hypothetical-protein
MMKDIGKLGIVIALFISSTFASAQEVKYPNIDGIGKESIGLAVLELALSKSGADYTVTVDKRSVNQNRARSMVESRDLDVFDTGFQKDLEQRFLPIYLPLEMGLLGWRVPIVHRDTEAQLGNVKNLEQLTKFSVGQGQGWGDIPILKNAGFKVVTASKIEKLIKMVDGQRFDLFPLGATEVYQFLDKFGSGSNNLVVDSNVTIVYPYGRFFYVTKDNLKLADAITTGMENALADGSLLNLLKQHPFSKDAFDKANLTNRVRVDIDSPDTKESFSQIDSRWWYTP
>NZ_CP045351.1|WP_152432032.1|364635_366531_-|ATP-binding-protein
MSKRYVSRIGRRVLLILVVISSVITLTTTGLQLYLDYDREFSDVEATHQEIKQVYSGLLATSLWFYDIPSLQKRLKELTTLPKVDYLEVGLDGEVISSGIKPEGSHVTSRFEIKYFDQNTDLEATVGELYVTSNSEKIYHFLLQQFFISLLLNAVKTFLVCSILFWVFHKSINARVISIVKYLRHYSPRYATSNLQMNNKHWTIEDMDELSWVADEINKLTCTFTKLYQSIKAEQEKLQDFTYVSSDWLWETDNTHRLTFCSDPMRAALGISEDKMPVVHKIQGLNRSVKLQEKLEQKKSFSMCQDEIEFDGKAYYFVFQAIAKYSGDVFVGFRGTAINVSELKQAQLELEKLNHSLEATIAMRTQALQESLRELESTQEKLVESEKMAALGGLVAGVAHEVNTPLGIAVTATSLVEDSLNKLSDSFDNQTLTSTEFTSESQIMDKGLSMLKANLERASILIKDFKNTAVDHISENQSEFNIRQMLDAVLVSLESETKKVPVSIELIGEEGITINSLLGVLTQVMSNLILNSVYHAFEQTSKPANILISYQQSEHGITFVYQDNGQGIALEDQQKVFEPFYTTKRGSGGSGLGLTLVYNLVTQKLKGEILLESSIGNGVRYKITLPKSLSK
>NZ_CP045351.1|WP_152432033.1|366632_367472_+|hypothetical-protein
MKIITLLLLSVLFSSVSAREIRYPNLDGIGQQSIGLAMLKLAIEKSGSDMTAIVDSNEVNQNRARQLVENGQLDIFDTGFDETLDGRFKPIYLPIDLGLTGWRLFIIHQDTQAKVENVKNVSQLSPFVMGQGQGWGDIRILEASGLKVTTAPRIEILIKMVGGKRFDLFPLGATEVHQFLETYRGNQKQLMVENQLVLIYPYGRFFYIRNNDKELSDVMHKGLEAAFEDGSLQELLINHPFSSDAFTKANLAERTHIRIPSPTLTEGFKAIDNKWWYVP
>NZ_CP045351.1|WP_152432755.1|367873_369166_-|diguanylate-cyclase
MVTNSKAWKPFSYLDDDQQPAGILIDYWQQFAKHNNVEIEFLLLDWNDSLEAVRTGKADVHAGLLWSEGREAYLDYTPEIITIDTQMYINRDLIGLDLNDFMLGKHNYKVGVVTGGYEEEFTRNNYPNLQLVSFNNNQKMIDAAFKGEISAFVADLQVGNFYLLTSNQPNAFIGVRNLYSGDLRAAVKEGNKALQDRIIKGQETITTSEKQRILSRWMHINTVYPAYLAPILIVIAVGGAILYIFALRYSVRMKTRELALANEELKKLSETDSLTGLSNRRHFVSEFQQRIEMQGDVCVIVFDIDDFKSINDNYGHQVGDHVIKTVAEAVREKIGSDQLLGRIGGEEFALVMNNQDELRVKEVSHVICDLIRNLDFSDKLPYQVTVSLGCAYYPTAHQDIQLSDADQLMYQAKAQGKDQAVVKNMENSHS
>NZ_CP045351.1|WP_152432034.1|369602_370835_+|MFS-transporter
MSKIDKATRILLAGFCINLCLGILYAWSVFNKALVTESGWSAAEASSPYAIATIAFSICLLIAGILQDKMGPRKILILGTILTGLGMIASGFANSPLMLNITFGVMTGAGIGFGYACLSPSAMKWFHSSKKGMVNGLIAAGFGLAAIYLAPLTSSLIESMGIQTSFIVLGIGILVITVPLAATISNPPADYAPASPHNKASKSTNPSAHDSDLTWKSMLKTPQFYSLWIMYAFAASVGLMIIGNITTIASIQADLPNAVYLASILAIFNSGGRVIAGLLADKIGGIRTLLLAFILQGINMVMFATFNSEFTLILGTAVAAVGYGTLLAVFPTITAEFYGLRNYGTNYGVLYTAWGIGGAIGAAVVGLSMSNVENYSLAYTISAFMMATCIALALFTKPISMAKLGRLKKA
>NZ_CP045351.1|WP_152432756.1|371022_373380_+|fatty-acid-cis/trans-isomerase
MNVRKLFILSLITLFAGCATYAGLNYDKLFGYAQPRERLVETSSPSSDFFINQVKPIIDNRCVVCHACYDAPCQLKLSSTAGIDRGASKALIYQGTRLTAATPTRLFEDAQNTSQWRDFDFNPVLNERTQSPTANIEAGLMAKMLMQKQTHPLPMQTQLEGFDFSINREQQCPTIEEYAEYESKYPDWGMPYGMPNLTSAEYSTLMSWLQDGALMNAPLPLTSEQGALVNKYEQFLNASPRKVQLMARYIYEHLFLSHLYFSDLKESSPRFFTLVRSTTPPGQAIKRITTRRPYDDPKTERVYYRLIPVESTIVDKTHMPFALNKQRLANWKKWFIDSKYDVAKLPDYSVEVAANPMTAFIDLPVKARFKFMLDNAQNTINAYIKGPVCRGQLALNVINDRFWVFFLDPDKSDIPEVNEFYRSQADNLKLPGELESNTVPITNWVSYSRQQARYLEAKSEFINKWFKDGQNLTTDVIWTGNGTNPNAALTVFRHFDSASVVQGLVGKPPKTAWVLDYALIERIHYLLVAGFDVYGNFGHQLMTRMFMDFLRLEGESNFITLLPKDIRHVEQSSWYEDQSSQLSDFLQRNVKPFNQPSQVPYQTDNPKKELYNILQTQLSPVLHNRYDIEQTGLSPESEQALATIDDLKGGGIRYFPQIIILHIESEAGQSQVFTLLHNNAHTNISSLFDEQRNRDFDNDDFTLVRGILGSYPAAFLSLSEKEIPLFVNMIAQVKQEQDYVKLLDKFAIRRSSTEFWSFSDKIHQWYKKDQPVEFGLLDYNRFENR
>NZ_CP045351.1|WP_114786331.1|373419_373608_+|hypothetical-protein
MSIRDSIRAIEQQIYIACSEGDYDTVQMLEHQLESLRGKAEHPLDDDSYAPESKIPPEDLWY
>NZ_CP045351.1|WP_152432035.1|373689_374106_-|RNA-binding-S4-domain-containing-protein
MTEDDKSTQEIEIEAIGVEVSSEPIELYKVFKLANLVGGGGEAKYIISEGYVAVNGELETRKRRKMYHGDVFEFNQEFYVVICDADNSEYERTVNDSVTEEVRHEVAKRQVKPEKADSKKANSSNKKNKIGRSDIDFF
>NZ_CP045351.1|WP_152432036.1|374207_375005_+|transporter-substrate-binding-domain-containing-protein
MLKWTLILLLLSWRAAAFEPPVKVLVYGDDAYPPYSYVENGIARGIYSDILRRVFEDMPGYKIKIVPIPWKRGLKMLKSGRGFALFPPYYYADKRLYISPYSKPILNEEVVVFCNNDSVQDRPLNNWPSDYLGLTIGVNEAFALGGNEFWNAVKAGKITISEAKGSRPSLLKLYEKKIDCYMNDRLSILWEIKRMTTEGLLPEDWKLTLGAVVSAEQGYLGFTTIQPEKYPYKDDFVETFNSILTQLKEKGEIEVIVKAYLEKDL
>NZ_CP045351.1|WP_152432037.1|375044_376637_-|dipeptide-ABC-transporter-ATP-binding-protein
MAKDILTLNNLSVGFGVGNEINKVTNKVSFTISKGETLALVGESGSGKSVTANSILKLLPKGSSHYLEGTINFDDIEILNCSERELRGIRGNRIGMIFQEPMVSLNPLHKVGRQLVETLAIHSGVRQTQAEKLAVEWLQKVDIRYPEVKINAYPHELSGGERQRVMIAMALINKPELLIADEPTTALDVSVQAQILELLRDLQKELGMAMLFITHDLSIVRRIADKVAVMQDGQIVEQADCYSLFSAPKHPYTQTLIHSDPRGLPVEVAEDSESLIKVDKLKVWFPVTGGLFKRVVSHIKAVTDMDFDLKRGHSMGIVGESGSGKSTTGMAILRLVNSEGSICYERHELQGLNRKEMLPYRSKMQVVFQDPFSALNPRMSVAQVIGEGLYVHHDFDELTVDKMICEAMEDVDLDPETRHRYPNEFSGGQRQRIAIARALVLKPEFILLDEPTSSLDRTVQLQVLDLLKSLQQKYALTYLFISHDLNVVKSLCHHTIVMKQGLIVESGRTDQLFEGPKRSYTRKLVELSSF

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP045351_1	1.1\|362373\|40\|NZ_CP045351\|PILER-CR	362373-362412	40	NZ_CP045351	Vibrio sp. THAF100 plasmid pTHAF100_a, complete sequence	362371-362410	0	1.0
NZ_CP045351_1	1.2\|362448\|40\|NZ_CP045351\|PILER-CR	362448-362487	40	NZ_CP045351	Vibrio sp. THAF100 plasmid pTHAF100_a, complete sequence	362446-362485	0	1.0

1. spacer 1.1|362373|40|NZ_CP045351|PILER-CR matches to NZ_CP045351 (Vibrio sp. THAF100 plasmid pTHAF100_a, complete sequence) position: , mismatch: 0, identity: 1.0

gttctctgctccaccaaacatcgaatgcatccatttcacg	CRISPR spacer
gttctctgctccaccaaacatcgaatgcatccatttcacg	Protospacer
****************************************

2. spacer 1.2|362448|40|NZ_CP045351|PILER-CR matches to NZ_CP045351 (Vibrio sp. THAF100 plasmid pTHAF100_a, complete sequence) position: , mismatch: 0, identity: 1.0

ctttttggctctaaaaaacatccaagccatactaaccact	CRISPR spacer
ctttttggctctaaaaaacatccaagccatactaaccact	Protospacer
****************************************

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP045350

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP045350_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045350_1

1228868-1231342

TypeI

I-C

Consensus_repeat	Method
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	CRISPRCasFinder
GTCGCACCTCCCNCAGGTGCGTGGATTGAAAC	CRT
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	PILER-CR

37 spacers

cas2,cas1,cas4,cas7,cas8c,cas5,cas3

The CRISPR arrays of NZ_CP045350_1

>merge|NZ_CP045350|1|1228868-1231342|CRISPRCasFinder,CRT,PILER-CR
GTCGCACCTCCCGCAGGTGCGTGGATTGAAACACTGAAAATTAAAGGCGAGTAGTCGTGATTTTTAGGTCGCACCTCCCGCAGGTGCGTGGATTGAAACAAGTTCGCGACCAACACAATAAGCAATATATACAGTCGCACCTCCCGCAGGTGCGTGGATTGAAACATGCAATTGTTACCTTTAGAGTTTGCGCTCTAGAGGTCGCACCTCCCGCAGGTGCGTGGATTGAAACTTTGAAGCAGTCAGCAGATTGAGAGGACAGATTAGTCGCACCTCCCGCAGGTGCGTGGATTGAAACCTTTATGGTTCTCATTTGCAATAAAAGAGTTATGTCGCACCTCCCGCAGGTGCGTGGATTGAAACTATTAAACTATTATTAGAGCGATAAGCTGCTTGAGTCGCACCTCCCGCAGGTGCGTGGATTGAAACTGATCGATGTGGTCAAATTGAATCTTGGCCAGCGTCGCACCTCCCGCAGGTGCGTGGATTGAAACAAATCTTATTGTTCAGTCAGGGCCAATCATTGAGGTCGCACCTCCCGCAGGTGCGTGGATTGAAACATTGTCATTAGGTAATAAAGAAATTAACACATGACGTCGCACCTCCCGCAGGTGCGTGGATTGAAACAGGATGTCACCGTATCTGTATCGGGTTCTAATGGCGTCGCACCTCCCGCAGGTGCGTGGATTGAAACAACCAAAGTATTACCAAACTTTAACGGTGTAGGCGGTCGCACCTCCCGCAGGTGCGTGGATTGAAACAACTAAAGCTCTTAACTTAGTCATCAAATTATCAATGTCGCACCTCCCGCAGGTGCGTGGATTGAAACCACTAATTCGTCTGTATTGTTAGTTTGTTCTATGAGTCGCACCTCCCGCAGGTGCGTGGATTGAAACATTACAGTAGTTAGCAACTTGTACCTTTTGCTCCGTCGCACCTCCCGCAGGTGCGTGGATTGAAACCTTACGTCTGGTTATAGCTTCCTCCTTAGTCTCAGTCGCACCTCCCGCAGGTGCGTGGATTGAAACTTGTTTATTCATAATCTGAATGAGACCGCCATTTGTCGCACCTCCCGCAGGTGCGTGGATTGAAACACATTTGGTTATACGTTCAATCATCATCTCTACTTGTCGCACCTCCCGCAGGTGCGTGGATTGAAACTTGAGCCTCGCGCTGCTTTTTTATTTCGCCGAAGTCGCACCTCCCGCAGGTGCGTGGATTGAAACAGGACTAATGACCAATTTGGAGTTAAGAGCCAAGTCGCACCTCCCGCAGGTGCGTGGATTGAAACTTTTGCTGATGGAATAACTATAACTATCCGCTTAGTCGCACCTCCCGCAGGTGCGTGGATTGAAACCGGAGGAGTTTTATATTCCTGAAGCTACGCAAATGTCGCACCTCCCGCAGGTGCGTGGATTGAAACATCTTTTTCTACAAAACCATCGGGTGAAAATAAGTCGCACCTCCCGCAGGTGCGTGGATTGAAACATCCAACGGATAGCATGTAAATTCTGTGCTTCATGTCGCACCTCCCGCAGGTGCGTGGATTGAAACTCTTTAATTGAAGCAGTTGGTTAAGTGAGGCTGGTCGCACCTCCCACAGGTGCGTGGATTGAAACAAATTCAATATTGATCGATTCTCCATTAACTGAGTCGCACCTCCCACAGGTGCGTGGATTGAAACCAATAAACATGCATCTCTGATTGATACTCTTTTGCGTCGCACCTCCCACAGGTGCGTGGATTGAAACTTGTTTGGCGGTTTCACCATTGGAATAGATATGGTCGCACCTCCCACAGGTGCGTGGATTGAAACAGCTATCACTAGCAGCGTTTCTAAGAAAGAACCACGTCGCACCTCCCACAGGTGCGTGGATTGAAACAAGACTCCATAGCTGATTCAGTTCACAGAGTGTTGTCGCACCTCCCACAGGTGCGTGGATTGAAACTAGTTTCCCGTATCACATGGAGATGTGTAGGTGGTCGCACCTCCCACAGGTGCGTGGATTGAAACATTGATGCTATCGCCGACAATGTAGCGAATACGGTCGCACCTCCCACAGGTGCGTGGATTGAAACTTAACTCCACGGTACAGAGCCTAATGCCCTATTGTCGCACCTCCCACAGGTGCGTGGATTGAAACTTTAAACCTCGTGGTGTTGTTATAGCTGCACATGAGTCGCACCTCCCACAGGTGCGTGGATTGAAACCTTTTGATATTCGAAATTATATTGATAAAGCTGCGTCGCACCTCCCACAGGTGCGTGGATTGAAACAGATCCTGATAAAGGAGTGGAATCGTGTGTTAAAGTCGCACCTCCCACGGGTGCGTGGATTGAAACAAATTACTGGCACTCTGACTATCAAAACCATCACGTCGCACCTCCCACAGGTGCGTGGATTGAAACAATTGACTGAGCATCAACCTCATCAGCTAATGTCGTCGCACCTCCCGCAGGTGCGTGGATTGAAAC

>NZ_CP045350|1|1|1228868-1231342|CRISPRCasFinder
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	ACTGAAAATTAAAGGCGAGTAGTCGTGATTTTTAG
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	AAGTTCGCGACCAACACAATAAGCAATATATACA
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	ATGCAATTGTTACCTTTAGAGTTTGCGCTCTAGAG
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	TTTGAAGCAGTCAGCAGATTGAGAGGACAGATTA
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	CTTTATGGTTCTCATTTGCAATAAAAGAGTTAT
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	TATTAAACTATTATTAGAGCGATAAGCTGCTTGA
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	TGATCGATGTGGTCAAATTGAATCTTGGCCAGC
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	AAATCTTATTGTTCAGTCAGGGCCAATCATTGAG
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	ATTGTCATTAGGTAATAAAGAAATTAACACATGAC
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	AGGATGTCACCGTATCTGTATCGGGTTCTAATGGC
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	AACCAAAGTATTACCAAACTTTAACGGTGTAGGCG
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	AACTAAAGCTCTTAACTTAGTCATCAAATTATCAAT
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	CACTAATTCGTCTGTATTGTTAGTTTGTTCTATGA
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	ATTACAGTAGTTAGCAACTTGTACCTTTTGCTCC
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	CTTACGTCTGGTTATAGCTTCCTCCTTAGTCTCA
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	TTGTTTATTCATAATCTGAATGAGACCGCCATTT
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	ACATTTGGTTATACGTTCAATCATCATCTCTACTT
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	TTGAGCCTCGCGCTGCTTTTTTATTTCGCCGAA
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	AGGACTAATGACCAATTTGGAGTTAAGAGCCAA
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	TTTTGCTGATGGAATAACTATAACTATCCGCTTA
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	CGGAGGAGTTTTATATTCCTGAAGCTACGCAAAT
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	ATCTTTTTCTACAAAACCATCGGGTGAAAATAA
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	ATCCAACGGATAGCATGTAAATTCTGTGCTTCAT
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	TCTTTAATTGAAGCAGTTGGTTAAGTGAGGCTG
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	AAATTCAATATTGATCGATTCTCCATTAACTGA
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	CAATAAACATGCATCTCTGATTGATACTCTTTTGC
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	TTGTTTGGCGGTTTCACCATTGGAATAGATATG
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	AGCTATCACTAGCAGCGTTTCTAAGAAAGAACCAC
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	AAGACTCCATAGCTGATTCAGTTCACAGAGTGTT
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	TAGTTTCCCGTATCACATGGAGATGTGTAGGTG
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	ATTGATGCTATCGCCGACAATGTAGCGAATACG
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	TTAACTCCACGGTACAGAGCCTAATGCCCTATT
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	TTTAAACCTCGTGGTGTTGTTATAGCTGCACATGA
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	CTTTTGATATTCGAAATTATATTGATAAAGCTGC
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	AGATCCTGATAAAGGAGTGGAATCGTGTGTTAAA
GTCGCACCTCCCACGGGTGCGTGGATTGAAAC	AAATTACTGGCACTCTGACTATCAAAACCATCAC
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	AATTGACTGAGCATCAACCTCATCAGCTAATGTC
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC

>NZ_CP045350|1|1|1228868-1231342|CRT
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	ACTGAAAATTAAAGGCGAGTAGTCGTGATTTTTAG
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	AAGTTCGCGACCAACACAATAAGCAATATATACA
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	ATGCAATTGTTACCTTTAGAGTTTGCGCTCTAGAG
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	TTTGAAGCAGTCAGCAGATTGAGAGGACAGATTA
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	CTTTATGGTTCTCATTTGCAATAAAAGAGTTAT
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	TATTAAACTATTATTAGAGCGATAAGCTGCTTGA
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	TGATCGATGTGGTCAAATTGAATCTTGGCCAGC
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	AAATCTTATTGTTCAGTCAGGGCCAATCATTGAG
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	ATTGTCATTAGGTAATAAAGAAATTAACACATGAC
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	AGGATGTCACCGTATCTGTATCGGGTTCTAATGGC
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	AACCAAAGTATTACCAAACTTTAACGGTGTAGGCG
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	AACTAAAGCTCTTAACTTAGTCATCAAATTATCAAT
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	CACTAATTCGTCTGTATTGTTAGTTTGTTCTATGA
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	ATTACAGTAGTTAGCAACTTGTACCTTTTGCTCC
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	CTTACGTCTGGTTATAGCTTCCTCCTTAGTCTCA
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	TTGTTTATTCATAATCTGAATGAGACCGCCATTT
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	ACATTTGGTTATACGTTCAATCATCATCTCTACTT
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	TTGAGCCTCGCGCTGCTTTTTTATTTCGCCGAA
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	AGGACTAATGACCAATTTGGAGTTAAGAGCCAA
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	TTTTGCTGATGGAATAACTATAACTATCCGCTTA
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	CGGAGGAGTTTTATATTCCTGAAGCTACGCAAAT
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	ATCTTTTTCTACAAAACCATCGGGTGAAAATAA
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	ATCCAACGGATAGCATGTAAATTCTGTGCTTCAT
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC	TCTTTAATTGAAGCAGTTGGTTAAGTGAGGCTG
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	AAATTCAATATTGATCGATTCTCCATTAACTGA
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	CAATAAACATGCATCTCTGATTGATACTCTTTTGC
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	TTGTTTGGCGGTTTCACCATTGGAATAGATATG
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	AGCTATCACTAGCAGCGTTTCTAAGAAAGAACCAC
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	AAGACTCCATAGCTGATTCAGTTCACAGAGTGTT
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	TAGTTTCCCGTATCACATGGAGATGTGTAGGTG
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	ATTGATGCTATCGCCGACAATGTAGCGAATACG
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	TTAACTCCACGGTACAGAGCCTAATGCCCTATT
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	TTTAAACCTCGTGGTGTTGTTATAGCTGCACATGA
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	CTTTTGATATTCGAAATTATATTGATAAAGCTGC
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	AGATCCTGATAAAGGAGTGGAATCGTGTGTTAAA
GTCGCACCTCCCACGGGTGCGTGGATTGAAAC	AAATTACTGGCACTCTGACTATCAAAACCATCAC
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	AATTGACTGAGCATCAACCTCATCAGCTAATGTC
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC

>NZ_CP045350|1|1|1230455-1231342|PILER-CR
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	AAATTCAATATTGATCGATTCTCCATTAACTGA
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	CAATAAACATGCATCTCTGATTGATACTCTTTTGC
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	TTGTTTGGCGGTTTCACCATTGGAATAGATATG
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	AGCTATCACTAGCAGCGTTTCTAAGAAAGAACCAC
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	AAGACTCCATAGCTGATTCAGTTCACAGAGTGTT
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	TAGTTTCCCGTATCACATGGAGATGTGTAGGTG
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	ATTGATGCTATCGCCGACAATGTAGCGAATACG
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	TTAACTCCACGGTACAGAGCCTAATGCCCTATT
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	TTTAAACCTCGTGGTGTTGTTATAGCTGCACATGA
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	CTTTTGATATTCGAAATTATATTGATAAAGCTGC
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	AGATCCTGATAAAGGAGTGGAATCGTGTGTTAAA
GTCGCACCTCCCACGGGTGCGTGGATTGAAAC	AAATTACTGGCACTCTGACTATCAAAACCATCAC
GTCGCACCTCCCACAGGTGCGTGGATTGAAAC	AATTGACTGAGCATCAACCTCATCAGCTAATGTC
GTCGCACCTCCCGCAGGTGCGTGGATTGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045350.1\|WP_152430153.1\|1234424_1242692_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|339516
NZ_CP045350.1\|WP_152430156.1\|1252208_1257590_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045350.1\|WP_152430150.1\|1231663_1232662_+\|DUF3289-family-protein	unknown	unknown	gnl\|CDD\|371671
NZ_CP045350.1\|WP_152430158.1\|1258092_1258404_-\|DUF1496-domain-containing-protein	unknown	unknown	gnl\|CDD\|369340
NZ_CP045350.1\|WP_152430155.1\|1251604_1252009_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|366645
NZ_CP045350.1\|WP_152430140.1\|1217161_1218103_+\|1-phosphofructokinase	unknown	unknown	gnl\|CDD\|274464
NZ_CP045350.1\|WP_152430145.1\|1223880_1225848_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	pfam09709_cas8c_CAS-I-C	gnl\|CDD\|378245
NZ_CP045350.1\|WP_152430144.1\|1223179_1223884_+\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|187782
NZ_CP045350.1\|WP_152430159.1\|1258506_1259400_-\|pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|225313
NZ_CP045350.1\|WP_152430148.1\|1227353_1228385_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NZ_CP045350.1\|WP_152430149.1\|1228397_1228691_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP045350.1\|WP_152430151.1\|1232658_1232934_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045350.1\|WP_152430147.1\|1226733_1227357_+\|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl\|CDD\|187768
NZ_CP045350.1\|WP_152430152.1\|1233011_1234112_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|334404
NZ_CP045350.1\|WP_152430143.1\|1220664_1223148_+\|CRISPR-associated-helicase-Cas3'	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|350688
NZ_CP045350.1\|WP_172971819.1\|1242831_1251288_+\|ParB-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|214678
NZ_CP045350.1\|WP_152430146.1\|1225864_1226734_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	cd09689_cas7_CAS-I-C	gnl\|CDD\|187820
NZ_CP045350.1\|WP_152430141.1\|1218341_1218953_+\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|379312
NZ_CP045350.1\|WP_152430157.1\|1257639_1258041_-\|DUF296-domain-containing-protein	unknown	unknown	gnl\|CDD\|224575
NZ_CP045350.1\|WP_152430142.1\|1218956_1220084_+\|HNH-endonuclease	unknown	unknown	gnl\|CDD\|379157

Protein	Function_ID	Function_description	E-value
NZ_CP045350.1\|WP_152430153.1\|1234424_1242692_+\|hypothetical-protein	gnl\|CDD\|339516	pfam15645, Tox-PLDMTX, Dermonecrotoxin of the Papain-like fold. A papain fold toxin domain found in bacterial polymorphic toxin systems.	9.76045e-23
NZ_CP045350.1\|WP_152430150.1\|1231663_1232662_+\|DUF3289-family-protein	gnl\|CDD\|371671	pfam11692, DUF3289, Protein of unknown function (DUF3289). This family of proteins with unknown function appears to be restricted to Proteobacteria.	7.10902e-36
NZ_CP045350.1\|WP_152430155.1\|1251604_1252009_+\|hypothetical-protein	gnl\|CDD\|366645	pfam01442, Apolipoprotein, Apolipoprotein A1/A4/E domain. These proteins contain several 22 residue repeats which form a pair of alpha helices. This family includes: Apolipoprotein A-I. Apolipoprotein A-IV. Apolipoprotein E.	0.003429
NZ_CP045350.1\|WP_152430140.1\|1217161_1218103_+\|1-phosphofructokinase	gnl\|CDD\|274464	TIGR03168, 1-PFK, hexose kinase, 1-phosphofructokinase family. This family consists largely of 1-phosphofructokinases, but also includes tagatose-6-kinases and 6-phosphofructokinases.	5.87769e-106
NZ_CP045350.1\|WP_152430145.1\|1223880_1225848_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	7.71643e-146
NZ_CP045350.1\|WP_152430144.1\|1223179_1223884_+\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|187782	cd09651, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	9.49344e-94
NZ_CP045350.1\|WP_152430159.1\|1258506_1259400_-\|pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|225313	COG2515, Acd, 1-aminocyclopropane-1-carboxylate deaminase [Amino acid transport and metabolism].	3.52079e-62
NZ_CP045350.1\|WP_152430148.1\|1227353_1228385_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	1.31188e-166
NZ_CP045350.1\|WP_152430149.1\|1228397_1228691_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	9.30442e-31
NZ_CP045350.1\|WP_152430158.1\|1258092_1258404_-\|DUF1496-domain-containing-protein	gnl\|CDD\|369340	pfam07383, DUF1496, Protein of unknown function (DUF1496). This family consists of several bacterial proteins of around 90 residues in length. Members of this family seem to be found exclusively in the Orders Vibrionales and Enterobacteriales. The function of this family is unknown.	1.66178e-18
NZ_CP045350.1\|WP_152430147.1\|1226733_1227357_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|187768	cd09637, Cas4_I-A_I-B_I-C_I-D_II-B, CRISPR/Cas system-associated protein Cas4. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas4 is RecB-like nuclease with three-cysteine C-terminal cluster.	1.56068e-38
NZ_CP045350.1\|WP_152430152.1\|1233011_1234112_-\|hypothetical-protein	gnl\|CDD\|334404	pfam01150, GDA1_CD39, GDA1/CD39 (nucleoside phosphatase) family.	4.90703e-46
NZ_CP045350.1\|WP_152430143.1\|1220664_1223148_+\|CRISPR-associated-helicase-Cas3'	gnl\|CDD\|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	6.17811e-49
NZ_CP045350.1\|WP_172971819.1\|1242831_1251288_+\|ParB-N-terminal-domain-containing-protein	gnl\|CDD\|214678	smart00470, ParB, ParB-like nuclease domain. Plasmid RK2 ParB preferentially cleaves single-stranded DNA. ParB also nicks supercoiled plasmid DNA preferably at sites with potential single-stranded character, like AT-rich regions and sequences that can form cruciform structures. ParB also exhibits 5-->3 exonuclease activity.	8.26656e-06
NZ_CP045350.1\|WP_152430146.1\|1225864_1226734_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|187820	cd09689, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Csd2 family.	9.08256e-109
NZ_CP045350.1\|WP_152430141.1\|1218341_1218953_+\|methyltransferase-domain-containing-protein	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.86778e-13
NZ_CP045350.1\|WP_152430157.1\|1257639_1258041_-\|DUF296-domain-containing-protein	gnl\|CDD\|224575	COG1661, COG1661, Predicted DNA-binding protein with PD1-like DNA-binding motif [General function prediction only].	6.91116e-30
NZ_CP045350.1\|WP_152430142.1\|1218956_1220084_+\|HNH-endonuclease	gnl\|CDD\|379157	pfam13391, HNH_2, HNH endonuclease.	3.27142e-11

>NZ_CP045350.1|WP_152430149.1|1228397_1228691_+|CRISPR-associated-endonuclease-Cas2
MMILVTYDVSFDSKNGQKRLRQLAKVCLDYGVRVQYSVFECEIDAAQWLHFKNKLLSIYDSEVDSLRFYKLGKNWQNKVEHYGAKVAIDIFRDTLIL
>NZ_CP045350.1|WP_152430148.1|1227353_1228385_+|type-I-C-CRISPR-associated-endonuclease-Cas1
MKKLQNSLYITKDGAYLHKQRETLLIEQKVDGKKQKLMQLPIHSIGNIFCFGNIMVSPQLLGFCGENGTHLSFFDMHGRFLANVVGKQTGNVLLRRQQFSIEEQAANDLAKHIVTAKIRSSRMLLLRFRRNHTTTPQIEKAIERLKQIIEQLKGVTTHDTILGLEGEAASHYFSAFAEMFKGNESKQLFDKRTRRPPKDPVNAVISLLYSVLGQEISGALQGVGLDPQVGFLHKERPGRNSLALDVLEEFRAYIVDSIALKLFNNKTLTTKDFDTDCLGGVTIKDEARKAVFQAYQTKKQEEVMHPFLQEKVQIGLLPHVQAMLLARHMRGDLAHYPPFVIKK
>NZ_CP045350.1|WP_152430147.1|1226733_1227357_+|CRISPR-associated-protein-Cas4
MLEARLVNISALQHFAFCQRQCALIHLEQVWQENYLTAHGRHLHERVDNGEPEMRKGVRFERGVVVSAPQLGLTGKLDLLEHHKASNQFIPVEYKRGKPKTNDIDKVQLCAQALCIEEMLNVEVKQGALWYWQIRKRIDIKLDNQLRTRTKSLITQVQQLFANVKTPSPTKGKHCKVCSLIDICQPDVTNNDSSSGYITALFNTDVE
>NZ_CP045350.1|WP_152430146.1|1225864_1226734_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MTLQNKIDFALIFNVLNANPNGDPLNGNRPRTDYDGFGEITDVCLKRKIRDRVQESGESIFVQSDEKKTDGMTSLRNRAESDDFGLGKDTFNSKKTAPEQAAKLCCEKWFDVRAFGQVFAFKGTGSDGVSIPIRGPVTIQSAFSIEPVSITSTQITKSVSGEGDGTKKSSDTMGMKHRVDNATYVTFGAITPQLAEKTGFSNEDADKIKNVLVKLFEGDASSARPEGSMSISHLIWWQHESKWGQYSSAKVHQTLRAHIEQGLPLETSALNDSLISSLDGLKPEVVEGF
>NZ_CP045350.1|WP_152430145.1|1223880_1225848_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MTWLTTLYKSYDELEKRNANLPFEQQVMPICHTLQNAHIHIAINSQGKFLRAEVLEKTQVVLPATEQSAGRSSGLCAHALADKIQYIAKDYVEFGGIKKSGFEFYHAQLKAWCDSEFSHPAVSAVYQYIAKGTVVADLIAEKVLYAQDRQLLTKWHDEGDSPALLKILPKEKGLFDQGSALVCWSVEIPGEPQSKTWLDPSIQQSWIAFDSENGDNTALCYATGENKLVASNHPAKIRHSGDKAKLISANDKSGYTFRGRFLSNDEACNISFEVTQKAHNALRCLLTKQSVFRNDTQVYLAWAVSGKEVPKFNELDLNDLASFLEQTDNVDHTQDLGQAYANQLKRYFKGIKTKNQLDDNEQIALLGLDSATPGRMGILYYRETIAKEFLARLEQWHRDLGWQQRVKINEQWQWVNSAPSLYRVLDGVYGDVLKSADTLKKNLITRLYPCIVEGKPIPQDIMQSAFHRAINRVAYKSDQTWLWLQNVSIACSLIKGFYTRTTNSIIRKEYPMALQQDNTSRDYLFGRLLALANKVEKIALSSSEANRLTTAERFMAQFVNRPSSTWLNISNALVPYQQRLFNNYQGYDKATKALISQITDMFEPADFNSNQKLSPEFLLGFHNQMIWLETHKVEKGQWVKKVNDEQVKENLAETV
>NZ_CP045350.1|WP_152430144.1|1223179_1223884_+|type-I-C-CRISPR-associated-protein-Cas5
MKNSISFRLWGKYALFTDPITKVGGEKCTYHIPTYEAIKGVLKSIYWKPTLVWHVDRVRVIKPLRTQTKGTKPLNWGGGNTLSYYTFLHDVEYQVEAHFEWNKNRPELEKDRIDGKHFSIAKRMLEKGGRQDIFLGTRDCQGYVEPCVFGEGEGAYDDIDELGFGLMFHSFGYPDETGNNELISRFWHGVMKNGVIEYPHVTACPVTRHVRKMSAKSFELEQNLRSAEQTESCL
>NZ_CP045350.1|WP_152430143.1|1220664_1223148_+|CRISPR-associated-helicase-Cas3'
MDELSSSQYYIAHPDLEYGHHQSVYAHLKAVSELSGRLAEKIGFADLGQLIGLMHDFGKYSSVFQNYMRLIITEHTSYNPDNDEGSGEIQNSKRLKGKIDHSSAGAQWVLKTLWPHLGKLKQQDQVLAPYGIAVIQALSMCIASHHSGLIDSLSENENVFANRIKKPDELTHQNECVKNADPELLSQAQSLASFELILESSQHIKGMFDKFELSAIEHDYYLGMFTKMLFSCLIDADRIDSADFEQPGNKPERLKQTNWVYACDKIEGFIAQLKPDNSIDHIRAQISENCFQRAQDETGVYSLTVPTGGGKTYASLRFALHHAQKHNLDRIIYIIPFTSIIEQNANAIRGVLGEENADDWVLEHHSSLEPEQQTWRSKLACENWDKPIVLTTMVQFLESMFASGTRGSRRMHQLSNAVLIFDEIQTLPIRCVHLFNNTINYLTRFCNTTALMCTATQPLLNQLPEQIKSFGELQLPLENELTPNIGKLYQQLERVCLNNLTKKGGWNETEITELVQKQLTAVQSCLVIVNTKAWAKALYQALQSQAINETKIFHLSTGMCSAHRKEILDEVRARLERGLATLCISTQLIEAGVDVDFGSVIRFVAGLDSIAQAAGRCNRNGKQQKGHVFVLNPAQENVGMLEDIKTGIAATTRIFTEFNEADLLKPEAMTRYFQYYFYERHKEMAYPIKQDQSLLNLLSGNSRNINNTNNTPFALKQSFMTAAKQFKAIDAPVHSVIVPFNDEARSIITQLCALDKRFDAETYRSLLKLAQKYSVNIFPNVWRKLNENQVVYSIAQDEAVFYLSEEFYSQDFGLSIEVIGVQQDLII
>NZ_CP045350.1|WP_152430142.1|1218956_1220084_+|HNH-endonuclease
MSYQYYLDKFRSLTMNNANGKKSPHKVCMLLAVMDLIQASVITSNKIEFNQVLKDRFTQHFEKFAQGNDKNTPENPYFFLRSEGFWHLSYNAGYEEASTSRYSAKAIAFAYLDQELFDYMRSFIVTNELKDALISNFSDMSSRYRQWLMDVGKTEETAGKYLGVIQGSISNWLMDTGDICEPITSIKSYRQFTKYEDKVRQLDIFKLTDEKEQGLYSEALSHYQRFLVELAQIDLNADIRQVMVDKTLTDTEKSIMVSARVGQGHFRAQLLQMWGGCAVTGYRNTQMLLASHIKPWRDSNHQERLDKFNGLLLLANLDKAFDLGFISFDDSGKVLISHYLEAPEVLGLTEDMSFNVMAEHKPYLRYHRGELFKGL
>NZ_CP045350.1|WP_152430141.1|1218341_1218953_+|methyltransferase-domain-containing-protein
MNSTLDFYHKHATRLAKQYDSLEFETVHRSWSTFWPKCGANVLDVGAGSGRDARWFAAQECSVVAVEPCKKFLQLAKKSSTQPICWVEDSLPHLQNVTTSSNHYDLILLSAVWMHLDHKQRTVAIKRLHELLASNGTLIVTLRDGEFKDGRETFGVSVNELSLLCSSAGFEIYHVATDDDSLNREDIRWQTVVIKKVGSLKEY
>NZ_CP045350.1|WP_152430140.1|1217161_1218103_+|1-phosphofructokinase
MKQTKWVTVTLNPAIDLSATANGFAVNQVNTVQEEQRDAAGKGINVGRVLSDLGAQVTLTGFLGQNNSELFESMFKQRGLNNNFVMVAGTNRTNIKIHDSSGDTTDINFNGFAVTQDDIKLLHKRLLKLANTHQGFIFSGSLPSNLDPHIVVSWIKELKSLGKKVVLDSSKEMLRQGISAKPWMIKPNETEISELLGKPIVTVSEGAAAAMELVNQGIDNVLLSMGEKGLIWVNQKQVLLSTPPVLKPVSTVGAGDSVVAAFCWASQFNQPNKQLANATAMGALAVSQTGVGLSSQAELQAMLKRIEVKEYKA
>NZ_CP045350.1|WP_152430150.1|1231663_1232662_+|DUF3289-family-protein
MRYESFPYVPEERQETTRERAARQRQERRAELTYTAKDQKRWAENRERVLAERKLAEEWKPVEGNFPLLVYQTQNKMDDFDAPDMTFGDETKEEIEQYGLMTPFEDDSINLPFTDIAVFGEDQFTLPVSEHFERMRSLANDVALGIGFSTKGETKDIFFEMVDKFERNEGGYYSNPSLTSALKEHETTANFHQALKKCLEESLKNGKLPSDIVSVSSQYMKSSKGKPLPQFLVGDILDPHKNLFDGTVLNVHGIWSMRVYVEQLEYKGSQIRGLFKYEVQDHFGLDKKDINNNPMNGDKPFELISGFRSWYLLQHYKEYAYKPFITKMDFSL
>NZ_CP045350.1|WP_152430151.1|1232658_1232934_+|hypothetical-protein
MMTFIRYSLLLLPLCWYVLIWDSIVFNGSIPRPTINNYPPWVDGLLVPIFWLVITPLSFFIGSIYTAYKKLWWWFAAYMILGFGFWVYLRI
>NZ_CP045350.1|WP_152430152.1|1233011_1234112_-|hypothetical-protein
MNIRELSYLAAILVSSSALADTTFVIDAGSSGSRLFEYQYHHDISSEHGLPVIDEQIQHKDIKGGIQTVKETDLNTYIDSLFVETKTIPDHLYFYSTAGMRTISATERNLVNQRVKDALAKRFPDADIKVKTITGQTEGAYAWLTANYFNGAFFNSQKTTGIMDLGGASTQITFETNTGDDLFNVTVGNLNFTLSSTSYLGLGQNLAISQYLNQAACFPKDYPLPNDQLGTGEFGECAEKVEPLINDVQSVNTKSAQLGAGSDLYAISGFFFNSSELGINDSFSLSKLKETGKHFCSQPWEEVEQGKTDYKLNPHLYAGCFNAAYQYTLISKGYQLTDDTNHITPIRELKGNAISWTLGPVLAPDL
>NZ_CP045350.1|WP_152430153.1|1234424_1242692_+|hypothetical-protein
MPDDSKVLVPYNVLNTSSDQVTPLLYAGSGLTSIETNRAAAERAAHEFPQTPRLPISKPEPSVSIEGLNVPQVLDKRVSTSADPLELVWQAWQDKYEQAKTFIEQGYNEQNIDIQRDLITELEQAKESITNIPAELSSPVDAVIADANNKSKGWIDELAKSDRANAYQLARHIDGSLKAVTEALKAFEHDQNLQLETWKEKVCAGYKQKHGLTQDTENLRHHMTLRRHAVRNRLQDVRHELESSKNKIQRKGWRNTFKREDEVKHYFTKVMNALEVVINDLKNKQTQFDPSFKDSAASMFVSKAGQSKEEKRQRGEHKQDKESKSINLADVEVAMGEQILKFEDAAVKAGKATKSTVAKMGEGAKNKMAKVAMQVARTPTYVAPTAMHLLHKARSPMAKSVNKALNRNLSDEDQIIRSIVRSLCWVLIQPAFRMQYDYAPLLGAAQTLAKSKPSTTDSADLLETVTEGSAATSGINKAASAQSEEVSGEAEKSRQEVLEPSLKKAEQASESLLAQVSLGGNGALKDVLKHYPLSDLTQLLEQLQSLSISEETPDTKIRPSLNRDVHTLKNLLAQEPSSRGAQLNQVSASERERLVNILSTIKDMGLSEQRFNKTVEYFLGLGQEVLTQKGQESLGKIVVKIEDALRKGEAYKKVRAMALRLRSRATKASDYQDSSLDSIIHKARFAGLAARDAYDELDSLALKHTGQPLGPFSRRSRVAKDWGMCANEVLREAGHTDAALIPDTEVIRHTLTERGMLTGLASDNDPLGIFFSTRVEGEWRYAYRGETIKPMSPADYAAQEKTLAEFIVSWSQKRLARGVIVSFIEGGVDVVGGLTVTPIKIGIRAGIKVPISLIRIGYDVHKIKQGVMPGEDKPYKVIKARITHRLEQLGFKMLMIPVGNTVKTVFAAGVSAAAHAHNAMVEKEEDKVKISSWAKVLGTEALLTGGSVPVSLGAKTAADLVMEPSPKLTTEEQQVVEQIKQALVGESASQEMDAVDESSPISNAYPDIDRGEGEYKEAVDKSLAKIARTHFGRDLIESMNKQGVEVTQPNEEERLRQEGGQTFYATYANPEQNTIFFDPWNTLAAESDEQANDKPWLRRDPSIALFHEMLHLYYHSHPVKVNYQSDWFKIDELGAKLAPEGASEEEKESLSHGIFEHFVAGADYDANDVHLAFSDPSFIEQSVQVGNGRYISENDYREAFYRAQGQAVIKRLDYGDSSFTGHDGDRYAPQSKTSNSENPISDFDELPDADKAEYEEYMNEVKTWQYELEGSGHIEITGTEEYFDNISEVLNDLNNTETGKKIFHGLNNGQTYFICPPTPEVGREGEYRNRVSTDISTNTIYFDPLTCVSIDSETDGAHLPTLMLAHELIHLIDYQNISLDINSDVMTQEQRDLLEHMAVGIKYIASDGTEIDFSIKDVKHEYLRDGAPAITVNQLREELGLPKRSAYISSEGNNSGHLFYQSNGQSNVHIALLEDNIRGLEQQLEWLEAKKRNTWKIRFIKRKALNKRILERRSRINRIRSQIADLRAQEAPTPVEVTPEPIGRPDLIDISNSPQLQAIVSVHEQLSQHLRSLSSSSLYAETADQLQLRILEELKGDSANVGQPLKLDYIDIGLPMKSLGEGWGIEVSVDTELIDHLLKVSFPGIAETINSSSPVIVTSDNGDGSQALSILNVGQLISAGRSSRLDTPWGRVPFQVFRVPPSIEPIQTVLKNVHDKISSEPQDRLNRIYTAKSRYQRLDQSLQQHYRLTPGDFDRRPTPQNVVNAMNNLKGAIAYLAYDYELFMVRPADLNSSREGYAGYVEMREMVNRLKGSLDSYLESETGTRYLEPKAAVVAKALSDGSLESTIGSEINSRLLEEATKISVQFPEILKPDSVIEITHVIHDEFLGELTSVVRMSVSDMLMKTIPTGEWRCVSNCIGGGEISNSDRDRIIPIVTQARYNIETEIPFQQHVDIMNSELEFVLDTLLKVHTQEFLNKNAVPHYQKQLLESFLSGQQKAYRCAYDGHIIHSSVFIPYDANNGQNQLGTMPNKDGLLYSPYSGFTWINSSNYSLSDVQQEAIRSGLAPQGKSVFDRSVSTKFIYDSTLNKRFPVDPLRNFDTQIGDMSFDPDTLSQYLTNSMSEYFDKVFDHQHDSLQEEWAKVHNNLKTAVALLSLIAIPVPQLSLALVAGNITVSIITLTDPSSSRSDKAWAIAEIGLEALGAIGDVITLSKGASRTLMTTLEQFGSDSAEFKRVLSQLTEAELVQQKGRGNKLFGIVHRPKKPAVPSPRFNPDPSVGTYTRVSQTAEESAAINEIKSQVVRLPKMEGYITTPAENCQNAAEIIHQHLRGVEGVENIKIGNIAIWDEFIGKPADMFDNHWVIFARYKGVDVVFDPTAGQFSKYGIQGPIFDTSNNWFAQYQNALGGYKNRKILAKIAYPDNFGSSAPYRSQEIRSAFDPVTSGDPKVLVQSRWYNEIGFDSNLKSQSKPLLKGGNDGFSWPKWKASKPESTNIKVFDTTNTDGDPIKANVVRKKVGEDFMLYTTDDGVQADALWVSVHGGYHASPSILSAAGKTGDMPVPEGVTIEFLGPHGMALEDPTIGLMNSRSLSPYSTVTSDGATHATGDLLDASGSNQVGHIKDYRMSKYQRSSGRGAETEDKIASALVKNRLFDGNRKTDVLTVRDRSLTLSTIGLSDMFEQLKLNNSQYKYVTFSGCRNELSVSNPVGYSVKGEQRMLITVDISGDVPRVVYARPITDLLQHVDGQGDSTDSRSSDD
>NZ_CP045350.1|WP_172971819.1|1242831_1251288_+|ParB-N-terminal-domain-containing-protein
MPDDSKVLVPYNVLNTSSDQVTPLLYAGSGLTSIETNRAAAERAAHEFPQTPRLPISKPEPSVSIEGLNVPQVLDKRVSTSADPLELVWQAWQDKYEQAKTFIEQGYNEQNIDIQRDLITELKQAKEAITNIPAGLSSPVDAVIADANSKSKGWIDELAKSDRANAYQLARHIDGSLKAVTEALKAFKHDQNLDLDSWKERVSAGYKQKHGLTQDTENLRHHMTLRRHAVRNRLQDVRHELESSKNKIQRKGWRNTFKREAEVKAYFDQVMNVLQVVIRDLKSKETKFDPSLKDSAASMFISKAGQSKEEKRQRGEHEQDKESESINLADVELAMGEQILKFEKAAIKAGKSTKNKMAKVAMQVARTPTYVAPTALHLLHKARSPMAKGVNKALNRNLSDEDQIIRSIVRSLCWTLIQPAFRMQYDYAPLLGAAQSLAKSKHSTTDSADVLETVTEGSAATSGINKAASAQSEEVSGEAEKSRQEVLEPSLKKAEQASESLLAQVSLGGNGALKDVLKHYPLSDLTQLLEQLQSLSLSEKTPDTKIRPSLGKDVQTLKSLLAQAPSNRGAELNQVSASERQRLVNILATIKDMGLSEQRFKDTVAYFLGIGQEVLSEQGQKSLGETVVKIEHALRKGEAYQKLRVQALRLRARATKASEYKDSSLDSLIHKARFAGLAARDAYDELDSLALKHTGQPLGPFSRRSRVAKDWGMCANEVLRDAGHTQAALIPNSEVIRDVLTERNMLTGLVSVKDPLGIFFSTRIAGEWRYAYRGETIKPMSPAEYAAQEKTLAEFIVSWSQKRLARGVIVSFIEGGVDVVGGLTVTPIKIGIRAGIKVPISLIRIGYDVHKIKQGVMPGEDKPYKVIKARITHRLEQLGFKMLMIPVGNTVKTVFAAGVSAAAHAHNAMVEKEEDKVKISSWAKVLGTEALLTGGSVPVSLGAKTAADLVMEPSPKLTTEEQQVVEQIKQALTGESEPQEVNALDESSPISDDYPDINRGQGEYKEAVDKSLAKIARTSFGRHLIESMNEQGIEITMPSDHTNTSDGDHDHDPSVGNYANPDNDTIFFDPHYKPSTEDIKGRPWLDCDPSVVLFHEMLHLYYSENPIQFEVSGQTYQFGGKGDPISEHMVAGADYVNEQKVEFRFSDPEWVKQHLKMGNYVNENDLRRALSQPIRKDYYFDARHTGAEQARYFNPSSPVEEEPTLDVAEPEFKDKIRPYNQIISEHREPNITLETGSSDESYSARQLIHSFCNAPDGFQLGLPKLLNLIDSGRFSEGVSNLVREWAAEYQAGYGIDRNILEKVLKDKGYAGLTDHAIVVSDDQNSVYVSSLDKIMASTHLRSGYLSGFTEGTGAISIAELQDIYKQYQSMSRLIGSTFEHFRNNTDRTSASVQLYRDPIEYISEGAVWPNLNTFSAVLEPDDERAFKSTLQKMDALEQALRLLYKEILGVEPAYKLGVESREDLAQQLDSFGEPGSEFIDEHPEYLNYRLTWRKIEALGGDIADYLASPSHLNWPMAEDGIGEDATELASSYRSMPTDAKQELYSNAVEYVLFQIGRDNLLSQGTRDAAYNARLKNEPCVVVDSTKPNSFFLPDSPGAKSGLYIDLNKPGQPYQRKANLTYQPSDLVSLNTLSQQLVTITDSHANNDEEVADLIQHVLPKSILGAQVPDLGVSAEQVQLELEYTFATSSFSEYLRSISRPFASLASQTQLMIDDGNGVTLQQTEKNQQQAEYIGAWIDTGIGVVTLFIPQGRVLNAAQSWAGIAADVADGKDPDPVDLAGAILGSIPGSRAGAQIDKFSKTGGQGVRVLLKVGEETVDLIDFGRGVKQACESGDPLDLFNVLLTTGMKAQDVIERAHQIKPDLADADIPKQNQWLIENGVDNGWGSSRPPLGVEGNPPVPGTTGRSLYGQAVPFRRPELDGGEWTGQSGTLPGTDADYFAYINAGGTPEGYYATLKEAEPAVTQSLFSFFGKQYQGRVQDGQFEVKKVGSDEWRAGHWWEEFTWRFKNRGGRVQSSAELDKRILKAAAKDTGFNFLCNLSAINTAQASGELPKGVATSLQSTKFNSPVYKQAFSLPASVMEPSGSSLVEGPLSKESITESGFIHTGVKDEDGNVHYEHVIYAYVQDGEVTLYQSNSNTFYEAFGGDIQQPSNNRVGQSSLTKIEWSEKTDTKLAEEQRTNPNLVYSFTPTNQVKNVADISVQQNGDVEVSAGEQTEVFSVGNNAQEIARIPFMNEGRRVEVRGYTSEFQGKAGQEALSIHGDRQGNFYLARQGHPMTAQQLVDYLKSQGVDLKSGSGPVHLLSCYSKSSGAAQALADVINRPVIGYSNREVQLPTLQQLTQNPVQIGSKMGKFDPRRFLAQSDFKPATPRVYHPRSDSSQGGSTSGRASLEMAGSGSGSNAKQMAFNALPQMQASPSWYSAENIYTPKTSAHGVIFKDPDNPDRLIKFYKRPSDKGIAENNRDVMNRLYGQDAELITLTGPDGQRYYAVNMPKMEGVSIEDIKDPQVMQDMLEKIEEGDFIAHWAGKLQDNGIRVEDLNLGSVLYDPSTGRFSLVDFDSSTISDSVSNAHYKQMYRSLHTPIRDVLIRQAKTLFAGQQDKLDLVNRVEGKLSQRFRHLMELDERGEASFSTLMEERTPAEVEVAVGARNQETASAGHADEPIQLSQGDWDSIPNKMEMFGADSEYFYEDFDGQIYKYEAADGEITYLGKQDGEYINLKNDQTWQPRHYNVAGQNAIKTWLTGDPATLYADTDRVIADRSASYDNERLENIRNGFDQGHYLPPIDVRWDNGVFKVINGNHRLKVAIEMGMESIPYRLIR
>NZ_CP045350.1|WP_152430155.1|1251604_1252009_+|hypothetical-protein
MSDESLEPSSTNPIKSLTSLATPLVFAESGLTSIDANRIKSHGKSFWHSLQDTFEDSAGLLKQEVSQQYHDIHDQVEAEFQEVKHTIESVPEEISKQLGSAVTDMKEKMSDYQIDKRIESSFDSLKNAFDVFKW
>NZ_CP045350.1|WP_152430156.1|1252208_1257590_+|hypothetical-protein
MTEEINPLNSLPPYVFGEVSNTNLSVSPSIDHLTTPLILPWNGISEDGTVSRSKRTRRDTYAFNPASSPVRLDTISEVHGRLTRRLASMSTSDLNSLSSEVFMMDQLNWLRCYFSSDPEALRYIDGDLRARSLCLQWNVHSDTDSVLLDDLLAVGFPGLTDGVSATSPAILVSRINSGGARTWDAFHVLPLGKIFGASDGMRLEAAWGRATCRPLYQKSDNYRRGYASGSTGLPLEVDAIKSPLLWAYNQIRSEGTDKTIRSITATERYDQLERDMQARFGFSQGEFERTSQDPEILSTLIRLQGAVAYLAYDHAVLTGSNPQLDPAGEGYVGYMNLRNMFTALLAGLRRYLATSQSNMLEVKAQALTAGTLLDTVNANMKNLLDEEVRKFVAKFSAKYPRISLTEGSTFLIRSLSVPLIAPVGPMGAVSYPIGSNPYTMERMALSDMLMKPIPSGEWYYPDGRPVSNGDKACIADEITKTRSDMDTEIPFRFDQVLRSKQADYTRVLGSALELHANQFVHNEANPAHQRELVEKFKKGKKPAYKCAFKGHTVYGSVFIPYSDDDSQTKYGSDLSKNGLLYSPYNGFVWLETDRFTDTQYVAMRNGLSIQGKAELDAAMEVKSLPATGLIYPGYMGMGGYVQIPPISVGPLQYFEGQVDSEHLTFNYSTTPLYLTNSISEYFDEVFLASHVSLQDRWDEIRDHLMLAVSILNIAAIPFPYLGLALIAGNITIAIVTLADRTSSTGDRAWAIADLVLEPLGAVGDILTLSKRATKMLTDIAQTSGANSPAFTRKLIELAQVELIKQPKRVNDKIVGIVGRIGDNSDYPSFATATLTPNVPSDGMCRGLAFKDAISRLNGSPIDNLTTEFSQNLSLADDVQVLHHTQPVVLNRSQVLSSGEARLATRKAVGTSERGGNSVSLDEEMTFSRANAEILVQLAKHDELSMVIGTRTHAVSLSKSGIGANAKLTLFDPAADQLFEWPLGNEKQNVADILNYIASNYDKGVSRQLGDNPLFLTVLTKSPESRHIYVPKAGMESLMTAVNQLDLDVSQGRLIQPIMVKNSAEKAALQADLVTLAATKPELKPLLDSLEIEELQLNRLSALSIENSALTVVGQSDVPASDIVTDLSALPKGYIDIRYLDARRAANDSMSVNHLTRQSSSEHLVIVGGTDIKATPSEALATAMESAGYSHTRVRDGKLTFPLNRTREEWNIIGLEQRGRAKNVIAQNSNQSGDSNGVALALRDNRERKLLYLTSPRDYRGHKTLRYYLDMGVEREQICVININPRDEQLPDDIQALGKVIILNSRSGIEVEPNQVYHALTGSLGKNKSQFIDKLEGYEEVERELKAFGVDEPSDVGQSTRHIAHDIAGGDSQATKNFFTRTWNAYQNQAVNAEVTQQVDEVYRQIKDSITREGWEGVSLVWSRGLNSEEYSKLRSLGDRNSLSVSSPIEQVEEVKSFKLLDEQKRNPHHLMTPQLYETLKEVNTKKKMLTIPIGDPIEYSPYHSALTGAAKQYYLNSDVSDALNLLQYWNKSSELRDVNHGKFNQGVFLQQLFKKLSEDGIPLQQVGLRSGEMEKGAYMGIPTLYLEEHNAAKGSARLLPVTRGGESAREADESQRVKDDATKIAQKTKQIQKFNNDILKNNDKLSNIRATDSTHPGIAGIVKNIEKLEAKKKTLEAEVAQLEESIKAYQLDASFSAPHRVVNEGDGLGGLPYFIRENLENYVGLYAAQNPADMQSLRLWLRDIASQGADTAFERIPEHIAKGTMTPFEVDVLVNYIEDVIANFTAYRTTYLP
>NZ_CP045350.1|WP_152430157.1|1257639_1258041_-|DUF296-domain-containing-protein
MIEPIVIRLTKGQDLKTQIQSLVTKHAIQAGSIASCVGSLEQVSLRLAGATQSITLTQPFEIVSMMGTLTPTHQHIHLSVADETGKVIGGHLLDNTIIDTTAELIIHHYPNLSFSRQQDNTTGYSELVIDTNK
>NZ_CP045350.1|WP_152430158.1|1258092_1258404_-|DUF1496-domain-containing-protein
MRKSFLAVFLILAGPVSANIITTPGKAVIAIDGGNAGKRVCYYQDQAYSLGAILQVGEHYMTCDRANDFETNGALKWIPLDQANQEKPSAQAADPNVKTYSIK
>NZ_CP045350.1|WP_152430159.1|1258506_1259400_-|pyridoxal-phosphate-dependent-enzyme
MKLNNSPITQHKFEGIEFFLKRDDMLHPQFSGNKARKFMYLLQSEQPQIKTLISYGSPQANSLYSLAALCKLKGWKLEYYVDRIPDWLRDKPIGNYGGALKLRAKVIAVHDTSFHPVDFIQTVRCPDSSCLVVAEGGREQDAQHGIKGLADEIVSWSQSQKSMDFVVALPSGTGTTSAYLQQFLKPYGIEVITCPCVGGKDYLIDQIQSLNIDSLPQIQQLGNKHHFGKLYHNDYQIWLALLEQTRVEFDLLYDPMMWQCLLNWHPNNSDKTILYIHQGGVLGNESMLPRYQRKFGR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP045350_1	1.23\|1230356\|34\|NZ_CP045350\|CRISPRCasFinder,CRT	1230356-1230389	34	NZ_CP007006	Vibrio parahaemolyticus UCM-V493 plasmid pVPUCMV, complete sequence	14901-14934	3	0.912
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	MN850644	Escherichia phage ekra, complete genome	15786-15819	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	MN655999	Shigella phage Z31, complete genome	17629-17662	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	MN850577	Escherichia phage heid, complete genome	39039-39072	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	MN850605	Escherichia phage fjerdesal, complete genome	41614-41647	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	MN994498	Phage NBEco004, complete genome	16080-16113	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	MN850585	Escherichia phage skuden, complete genome	81691-81724	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	MT322327	UNVERIFIED: Escherichia phage SSBS18_WS_10_728, complete genome	54300-54333	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	MK295205	Shigella phage vB_SflM_004, complete genome	22525-22558	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	NC_041979	Escherichia coli O157 typing phage 1, complete genome	42609-42642	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	MN850631	Escherichia phage mio, complete genome	17366-17399	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	MN850639	Escherichia phage radambza, complete genome	68419-68452	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	MK482688	Escherichia phage vB_EcoM_LMP25, complete genome	17920-17953	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	KF055347	Escherichia phage JH2, complete genome	13266-13299	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	NC_042096	Salmonella phage BPS17L1, complete genome	13952-13985	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	NC_027360	Enterobacteriaphage UAB_Phi87, complete genome	30973-31006	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	KP869113	Escherichia coli O157 typing phage 15, partial genome	59370-59403	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	MN850633	Escherichia phage allfine, complete genome	61244-61277	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	MN850619	Escherichia phage finno, complete genome	33659-33692	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	KT184313	Enterobacteria phage KhF1, complete genome	8710-8743	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	KT184315	Enterobacteria phage KhF3, complete genome	59202-59235	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	KC139526	Salmonella phage FSL SP-010 hypothetical proteins, putative PseT polynucleotide 5'-kinase/3'-phosphatase, hypothetical protein, rIIB protein, rIIA protein, hypothetical proteins, nicotinamide phosphoribosyl transferase, putative ribose-phosphate pyrophosphokinase, hypothetical proteins, ribonucleotide reductase of class III, hypothetical proteins, ribonucleotide reductase of class III, HNH homing endonuclease, ribonucleotide reductase of class III, hypothetical protein, putative glutaredoxin, ribonucleoside triphosphate reductase, beta chain, hypothetical protein, ribonucleoside triphosphate reductase alpha chain, hypothetical proteins, NAD synthetase, putative HNH endonuclease, putative exodeoxyribonuclease, hypothetical proteins, putative phage DNA primase/helicase, hypothetical protein, putative deoxynucleotide monophosphate kinase, hypothetical proteins, putative DNA polymerase, endonuclease, putative DNA polymerase, hypothetical proteins, ATP-dependent DNA ligase, hypothetical proteins, putative transcriptional regulatory protein, hypothetical proteins, dihydrofolate reductase, thymidylate synthase, and hypothetical proteins genes, complete cds; and tail fiber protein gene, partial cds	8789-8822	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	MH586731	Salmonella phage Meda, complete genome	2980-3013	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	KT184314	Enterobacteria phage KhF2, complete genome	31840-31873	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	KP869110	Escherichia coli O157 typing phage 12, complete genome	28390-28423	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	MN850647	Escherichia phage tootiki, complete genome	71124-71157	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	NC_005282	Enterobacteria phage Felix 01, complete genome	85467-85500	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	JF461087	Salmonella phage FO1a, complete genome	82718-82751	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	MK482690	Escherichia phage vB_EcoM_LMP34, partial genome	76308-76341	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	MK482689	Escherichia phage vB_EcoM_LMP33, complete genome	47300-47333	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	MN994499	Phage NBEco005, complete genome	71970-72003	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	KC139638	Salmonella phage FSL SP-107 thymidylate synthase, dihydrofolate reductase, hypothetical proteins, putative transcriptional regulatory protein, hypothetical proteins, ATP-dependent DNA ligase, hypothetical proteins, putative DNA polymerase, endonuclease, putative DNA polymerase, hypothetical proteins, putative deoxynucleotide monophosphate kinase, hypothetical protein, putative phage DNA primase/helicase, hypothetical proteins, putative exodeoxyribonuclease, NAD synthetase, hypothetical proteins, ribonucleoside triphosphate reductase, alpha chain, hypothetical protein, ribonucleoside triphosphate reductase, beta chain, putative glutaredoxin, hypothetical protein, ribonucleotide reductase of class III, hypothetical proteins, ribonucleotide reductase of class III, hypothetical proteins, putative ribose-phosphate pyrophosphokinase, nicotinamide phosphoribosyl transferase, hypothetical proteins, rIIA protein, rIIB protein, hypothetical protein, putative PseT polynucleotide 5'-kinase/3'-phosphatase, and hypothetical proteins genes, complete cds	32492-32525	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	MN994503	Phage NBSal004, complete genome	70718-70751	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	MH571750	Escherichia phage vB_EcoM-Ro111lw, complete genome	71084-71117	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	NC_012749	Enterobacteria phage WV8, complete genome	87800-87833	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	LR699048	Escherichia phage VpaE1_ev035 genome assembly, chromosome: 1	86972-87005	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	MK965970	Salmonella phage DaR-2019b isolate 6717_4FA, complete genome	56087-56120	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	LC519489	Escherichia phage SP22 DNA, complete genome	86639-86672	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	EU877232	Enterobacteria phage WV8, complete sequence	87800-87833	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	MT446388	UNVERIFIED: Escherichia virus TH10, complete genome	80456-80489	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	MN850637	Escherichia phage warpig, complete genome	28172-28205	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	KC139544	Salmonella phage FSL SP-012 hypothetical protein gene, partial cds; and hypothetical proteins, thymidylate synthase, dihydrofolate reductase, hypothetical proteins, putative transcriptional regulatory protein, hypothetical proteins, ATP-dependent DNA ligase, hypothetical proteins, putative DNA polymerase, endonuclease, putative DNA polymerase, hypothetical proteins, putative deoxynucleotide monophosphate kinase, hypothetical protein, putative phage DNA primase/helicase, hypothetical proteins, putative exodeoxyribonuclease, hypothetical protein, NAD synthetase, hypothetical proteins, ribonucleoside triphosphate reductase alpha chain, hypothetical protein, ribonucleoside triphosphate reductase beta chain, putative glutaredoxin, hypothetical protein, ribonucleotide reductase of class III, homing endonuclease, ribonucleotide reductase of class III, hypothetical proteins, ribonucleotide reductase of class III, hypothetical proteins, putative ribose-phosphate pyrophosphokinase, nicotinamide phosphoribosyl transferase, hypothetical proteins, rIIA protein, rIIB protein, hypothetical protein, putative PseT polynucleotide 5'-kinase/3'-phosphatase, and hypothetical proteins genes, complete cds	33157-33190	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	MH051914	Enterobacteria phage vB_EcoM_IME338, complete genome	85063-85096	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	KP869106	Escherichia coli O157 typing phage 8, partial genome	18164-18197	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	KR014248	Escherichia phage vB_EcoM_AYO145A, complete genome	86685-86718	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	KP869109	Escherichia coli O157 typing phage 11, complete genome	85830-85863	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	AF320576	Bacteriophage Felix 01, complete genome	85467-85500	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	JX560968	Escherichia phage EC6, complete genome	72941-72974	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	MK965969	Salmonella phage DaR-2019a isolate 6712_28b, complete genome	56785-56818	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	KX377933	Escherichia phage vB_EcoM_Alf5, complete genome	86700-86733	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	NC_031939	Salmonella phage BPS15Q2, complete genome	74059-74092	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	MN850566	Escherichia phage garuso, complete genome	34019-34052	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	LR597658	Escherichia phage VpaE1_ev108 genome assembly, chromosome: 1	87125-87158	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	KT184316	Enterobacteria phage XTG1, complete genome	61426-61459	7	0.794
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	NC_027337	Escherichia phage vB_EcoM-VpaE1, complete genome	87791-87824	7	0.794
NZ_CP045350_1	1.33\|1231012\|35\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231012-1231046	35	MN693114	Marine virus AFVG_25M536, complete genome	20971-21005	8	0.771
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	MN481367	Salmonella phage D1-2, complete genome	14181-14214	8	0.765
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	MT833282	Escherichia coli phage vB_EcoM_Shy, complete genome	88073-88106	8	0.765
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	MG969404	UNVERIFIED: Salmonella phage GE_vB_7A, complete genome	69984-70017	8	0.765
NZ_CP045350_1	1.34\|1231079\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231079-1231112	34	MK524176	Escherichia phage PHB11, complete genome	71382-71415	8	0.765
NZ_CP045350_1	1.18\|1230029\|33\|NZ_CP045350\|CRISPRCasFinder,CRT	1230029-1230061	33	NZ_CP049159	Caballeronia sp. SBC1 plasmid pSBC1_3, complete sequence	477025-477057	9	0.727
NZ_CP045350_1	1.18\|1230029\|33\|NZ_CP045350\|CRISPRCasFinder,CRT	1230029-1230061	33	NZ_CP049320	Caballeronia sp. SBC2 plasmid pSBC2-4, complete sequence	29178-29210	9	0.727
NZ_CP045350_1	1.37\|1231277\|34\|NZ_CP045350\|CRISPRCasFinder,CRT,PILER-CR	1231277-1231310	34	NZ_CP032488	Yersinia hibernica strain CFS1934 plasmid pCFS1934, complete sequence	5862-5895	11	0.676

1. spacer 1.23|1230356|34|NZ_CP045350|CRISPRCasFinder,CRT matches to NZ_CP007006 (Vibrio parahaemolyticus UCM-V493 plasmid pVPUCMV, complete sequence) position: , mismatch: 3, identity: 0.912

atccaacggatagcatgtaaattctgtgcttcat	CRISPR spacer
atccaacgtatagcatgtatattctgtgcttcgt	Protospacer
******** ********** ************.*

2. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to MN850644 (Escherichia phage ekra, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

3. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to MN655999 (Shigella phage Z31, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

4. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to MN850577 (Escherichia phage heid, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

5. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to MN850605 (Escherichia phage fjerdesal, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

6. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to MN994498 (Phage NBEco004, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

7. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to MN850585 (Escherichia phage skuden, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

8. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to MT322327 (UNVERIFIED: Escherichia phage SSBS18_WS_10_728, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

9. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to MK295205 (Shigella phage vB_SflM_004, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

10. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to NC_041979 (Escherichia coli O157 typing phage 1, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

11. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to MN850631 (Escherichia phage mio, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

12. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to MN850639 (Escherichia phage radambza, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

13. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to MK482688 (Escherichia phage vB_EcoM_LMP25, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

14. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to KF055347 (Escherichia phage JH2, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

15. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to NC_042096 (Salmonella phage BPS17L1, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

16. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to NC_027360 (Enterobacteriaphage UAB_Phi87, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

17. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to KP869113 (Escherichia coli O157 typing phage 15, partial genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

18. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to MN850633 (Escherichia phage allfine, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

19. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to MN850619 (Escherichia phage finno, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

20. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to KT184313 (Enterobacteria phage KhF1, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

21. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to KT184315 (Enterobacteria phage KhF3, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

22. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to KC139526 (Salmonella phage FSL SP-010 hypothetical proteins, putative PseT polynucleotide 5'-kinase/3'-phosphatase, hypothetical protein, rIIB protein, rIIA protein, hypothetical proteins, nicotinamide phosphoribosyl transferase, putative ribose-phosphate pyrophosphokinase, hypothetical proteins, ribonucleotide reductase of class III, hypothetical proteins, ribonucleotide reductase of class III, HNH homing endonuclease, ribonucleotide reductase of class III, hypothetical protein, putative glutaredoxin, ribonucleoside triphosphate reductase, beta chain, hypothetical protein, ribonucleoside triphosphate reductase alpha chain, hypothetical proteins, NAD synthetase, putative HNH endonuclease, putative exodeoxyribonuclease, hypothetical proteins, putative phage DNA primase/helicase, hypothetical protein, putative deoxynucleotide monophosphate kinase, hypothetical proteins, putative DNA polymerase, endonuclease, putative DNA polymerase, hypothetical proteins, ATP-dependent DNA ligase, hypothetical proteins, putative transcriptional regulatory protein, hypothetical proteins, dihydrofolate reductase, thymidylate synthase, and hypothetical proteins genes, complete cds; and tail fiber protein gene, partial cds) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

23. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to MH586731 (Salmonella phage Meda, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

24. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to KT184314 (Enterobacteria phage KhF2, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

25. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to KP869110 (Escherichia coli O157 typing phage 12, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

26. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to MN850647 (Escherichia phage tootiki, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

27. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to NC_005282 (Enterobacteria phage Felix 01, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

28. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to JF461087 (Salmonella phage FO1a, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

29. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to MK482690 (Escherichia phage vB_EcoM_LMP34, partial genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

30. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to MK482689 (Escherichia phage vB_EcoM_LMP33, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

31. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to MN994499 (Phage NBEco005, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

32. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to KC139638 (Salmonella phage FSL SP-107 thymidylate synthase, dihydrofolate reductase, hypothetical proteins, putative transcriptional regulatory protein, hypothetical proteins, ATP-dependent DNA ligase, hypothetical proteins, putative DNA polymerase, endonuclease, putative DNA polymerase, hypothetical proteins, putative deoxynucleotide monophosphate kinase, hypothetical protein, putative phage DNA primase/helicase, hypothetical proteins, putative exodeoxyribonuclease, NAD synthetase, hypothetical proteins, ribonucleoside triphosphate reductase, alpha chain, hypothetical protein, ribonucleoside triphosphate reductase, beta chain, putative glutaredoxin, hypothetical protein, ribonucleotide reductase of class III, hypothetical proteins, ribonucleotide reductase of class III, hypothetical proteins, putative ribose-phosphate pyrophosphokinase, nicotinamide phosphoribosyl transferase, hypothetical proteins, rIIA protein, rIIB protein, hypothetical protein, putative PseT polynucleotide 5'-kinase/3'-phosphatase, and hypothetical proteins genes, complete cds) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

33. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to MN994503 (Phage NBSal004, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

34. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to MH571750 (Escherichia phage vB_EcoM-Ro111lw, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

35. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to NC_012749 (Enterobacteria phage WV8, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

36. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to LR699048 (Escherichia phage VpaE1_ev035 genome assembly, chromosome: 1) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

37. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to MK965970 (Salmonella phage DaR-2019b isolate 6717_4FA, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

38. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to LC519489 (Escherichia phage SP22 DNA, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaatcagct--	Protospacer
.*  ************* *******.**  ****

39. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to EU877232 (Enterobacteria phage WV8, complete sequence) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

40. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to MT446388 (UNVERIFIED: Escherichia virus TH10, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

41. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to MN850637 (Escherichia phage warpig, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

42. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to KC139544 (Salmonella phage FSL SP-012 hypothetical protein gene, partial cds; and hypothetical proteins, thymidylate synthase, dihydrofolate reductase, hypothetical proteins, putative transcriptional regulatory protein, hypothetical proteins, ATP-dependent DNA ligase, hypothetical proteins, putative DNA polymerase, endonuclease, putative DNA polymerase, hypothetical proteins, putative deoxynucleotide monophosphate kinase, hypothetical protein, putative phage DNA primase/helicase, hypothetical proteins, putative exodeoxyribonuclease, hypothetical protein, NAD synthetase, hypothetical proteins, ribonucleoside triphosphate reductase alpha chain, hypothetical protein, ribonucleoside triphosphate reductase beta chain, putative glutaredoxin, hypothetical protein, ribonucleotide reductase of class III, homing endonuclease, ribonucleotide reductase of class III, hypothetical proteins, ribonucleotide reductase of class III, hypothetical proteins, putative ribose-phosphate pyrophosphokinase, nicotinamide phosphoribosyl transferase, hypothetical proteins, rIIA protein, rIIB protein, hypothetical protein, putative PseT polynucleotide 5'-kinase/3'-phosphatase, and hypothetical proteins genes, complete cds) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

43. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to MH051914 (Enterobacteria phage vB_EcoM_IME338, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

44. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to KP869106 (Escherichia coli O157 typing phage 8, partial genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

45. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to KR014248 (Escherichia phage vB_EcoM_AYO145A, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

46. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to KP869109 (Escherichia coli O157 typing phage 11, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

47. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to AF320576 (Bacteriophage Felix 01, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

48. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to JX560968 (Escherichia phage EC6, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

49. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to MK965969 (Salmonella phage DaR-2019a isolate 6712_28b, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

50. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to KX377933 (Escherichia phage vB_EcoM_Alf5, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

51. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to NC_031939 (Salmonella phage BPS15Q2, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

52. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to MN850566 (Escherichia phage garuso, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

53. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to LR597658 (Escherichia phage VpaE1_ev108 genome assembly, chromosome: 1) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

54. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to KT184316 (Enterobacteria phage XTG1, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

55. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to NC_027337 (Escherichia phage vB_EcoM-VpaE1, complete genome) position: , mismatch: 7, identity: 0.794

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcagct--	Protospacer
.*  ************* *******.**  ****

56. spacer 1.33|1231012|35|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to MN693114 (Marine virus AFVG_25M536, complete genome) position: , mismatch: 8, identity: 0.771

tttaaacctcgtggtgttgttatagctgcacatga-	CRISPR spacer
gctaaacttcctggtgttgttatagctg-atataga	Protospacer
 .*****.** ***************** *.**..

57. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to MN481367 (Salmonella phage D1-2, complete genome) position: , mismatch: 8, identity: 0.765

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcaact--	Protospacer
.*  ************* *******.**  *.**

58. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to MT833282 (Escherichia coli phage vB_EcoM_Shy, complete genome) position: , mismatch: 8, identity: 0.765

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcaact--	Protospacer
.*  ************* *******.**  *.**

59. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to MG969404 (UNVERIFIED: Salmonella phage GE_vB_7A, complete genome) position: , mismatch: 8, identity: 0.765

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcaact--	Protospacer
.*  ************* *******.**  *.**

60. spacer 1.34|1231079|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to MK524176 (Escherichia phage PHB11, complete genome) position: , mismatch: 8, identity: 0.765

cttttgatattcgaaattatattgataa--agctgc	CRISPR spacer
ttggtgatattcgaaataatattgacaagcaact--	Protospacer
.*  ************* *******.**  *.**

61. spacer 1.18|1230029|33|NZ_CP045350|CRISPRCasFinder,CRT matches to NZ_CP049159 (Caballeronia sp. SBC1 plasmid pSBC1_3, complete sequence) position: , mismatch: 9, identity: 0.727

ttgagcctcgcgctgcttttttatttcgccgaa	CRISPR spacer
gtcagcctcgcgctgctgttctatttcctgcca	Protospacer
 * ************** **.****** .   *

62. spacer 1.18|1230029|33|NZ_CP045350|CRISPRCasFinder,CRT matches to NZ_CP049320 (Caballeronia sp. SBC2 plasmid pSBC2-4, complete sequence) position: , mismatch: 9, identity: 0.727

ttgagcctcgcgctgcttttttatttcgccgaa	CRISPR spacer
gtcagcctcgcgctgctgttctatttcctgcca	Protospacer
 * ************** **.****** .   *

63. spacer 1.37|1231277|34|NZ_CP045350|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP032488 (Yersinia hibernica strain CFS1934 plasmid pCFS1934, complete sequence) position: , mismatch: 11, identity: 0.676

aattgactgagcatcaacctcatcagctaatgtc	CRISPR spacer
aaatgactgaccatcaacctcatccagaggctcc	Protospacer
** ******* ************* .  ... .*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

193156 : 201192

Cafeteria_roenbergensis_virus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_152429332.1\|193156_193954_+	3-deoxy-8-phosphooctulonate synthase	E3T537	Cafeteria_roenbergensis_virus	1.5e-44	40.0
WP_152429333.1\|193956_194520_+	HAD hydrolase family protein	A0A140XBD6	Dickeya_phage	8.5e-23	38.5
WP_152429334.1\|194523_195276_+	3-deoxy-manno-octulosonate cytidylyltransferase	NA	NA	NA	NA
WP_152429335.1\|195276_196212_+	KpsF/GutQ family sugar-phosphate isomerase	A0A2P0VNK5	Tetraselmis_virus	4.5e-29	29.7
WP_152429336.1\|196371_197208_+	glycosyltransferase	F2Y1U7	Organic_Lake_phycodnavirus	4.1e-21	31.9
WP_152429337.1\|197372_198374_+	sugar transferase	NA	NA	NA	NA
WP_152429338.1\|198648_198984_+	DUF3135 domain-containing protein	NA	NA	NA	NA
WP_114785960.1\|199177_199471_+	co-chaperone GroES	A0A221S331	uncultured_virus	3.0e-11	40.4
WP_152429339.1\|199554_201192_+	chaperonin GroEL	A0A2I7SAK5	Vibrio_phage	1.7e-188	67.4

DBSCAN-SWA_2

609151 : 618639

Faustovirus(14.29%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_152429636.1\|609151_610366_+	IscS subfamily cysteine desulfurase	A0A1X7C038	Faustovirus	4.8e-31	29.9
WP_114788027.1\|610417_610798_+	Fe-S cluster assembly scaffold IscU	A0A218MKD1	uncultured_virus	2.4e-53	79.0
WP_114788028.1\|610867_611191_+	iron-sulfur cluster assembly protein IscA	A0A2H4N7N5	Lake_Baikal_phage	4.0e-25	52.3
WP_152429637.1\|611238_611754_+	co-chaperone HscB	NA	NA	NA	NA
WP_152429638.1\|611773_613627_+	Fe-S protein assembly chaperone HscA	A0A0N9QXN8	Chrysochromulina_ericina_virus	4.1e-106	39.9
WP_114788031.1\|613638_613977_+	ISC system 2Fe-2S type ferredoxin	NA	NA	NA	NA
WP_152429639.1\|614023_614218_+	Fe-S cluster assembly protein IscX	NA	NA	NA	NA
WP_152429640.1\|614380_615679_+	aminopeptidase PepB	Q6GYZ8	Mycoplasma_phage	1.3e-34	34.0
WP_152429641.1\|615728_616157_+	nucleoside-diphosphate kinase	A0A2P1ELL9	Moumouvirus	2.7e-21	42.9
WP_152429642.1\|616551_618639_+	elongation factor G	E4ZFJ7	Streptococcus_phage	2.6e-61	27.8

DBSCAN-SWA_3

1424292 : 1492864

Indivirus(11.11%)

transposase,lysis,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_152430296.1\|1424292_1424970_-\|lysis	CidB/LrgB family autolysis modulator	NA	NA	NA	NA
WP_152430297.1\|1424969_1425335_-	CidA/LrgA family protein	NA	NA	NA	NA
WP_152431677.1\|1425480_1426905_-	exodeoxyribonuclease I	NA	NA	NA	NA
WP_152430298.1\|1427014_1427776_-	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_152430299.1\|1427929_1429303_-	cation:dicarboxylase symporter family transporter	NA	NA	NA	NA
WP_152430300.1\|1429465_1430152_-	NAD(P)H-binding protein	NA	NA	NA	NA
WP_152430301.1\|1430824_1431853_+	succinylglutamate desuccinylase	NA	NA	NA	NA
WP_152430302.1\|1431955_1432951_+	vitamin B12 ABC transporter permease BtuC	NA	NA	NA	NA
WP_152430303.1\|1432937_1433693_+	vitamin B12 ABC transporter ATP-binding protein BtuD	A0A1V0SE00	Indivirus	3.7e-13	28.1
WP_152430304.1\|1433754_1434330_-	SAM-dependent methyltransferase	A0A088C537	Shewanella_sp._phage	1.3e-34	43.7
WP_152430305.1\|1434504_1435548_+	diguanylate cyclase	A0A127AWB9	Bacillus_phage	1.9e-15	34.5
WP_152430306.1\|1435594_1436161_-	DUF1415 family protein	NA	NA	NA	NA
WP_152430307.1\|1436206_1437421_-	MFS transporter	NA	NA	NA	NA
WP_152430308.1\|1437536_1438406_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_152430309.1\|1438529_1439744_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_152430310.1\|1439767_1442206_+	PAS domain S-box protein	Q8QKV7	Ectocarpus_siliculosus_virus	4.2e-34	29.0
WP_152430311.1\|1442209_1442437_-	glutaredoxin family protein	NA	NA	NA	NA
WP_152430312.1\|1442549_1443053_+	DUF45 domain-containing protein	NA	NA	NA	NA
WP_152430313.1\|1443144_1443345_+	hypothetical protein	NA	NA	NA	NA
WP_152430314.1\|1443341_1444007_-	type IV pilus biogenesis/stability protein PilW	NA	NA	NA	NA
WP_172971821.1\|1444128_1444935_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_152430316.1\|1445435_1452731_+	hypothetical protein	NA	NA	NA	NA
WP_152430317.1\|1453919_1454285_+	hypothetical protein	NA	NA	NA	NA
WP_152430318.1\|1454369_1454771_+	hypothetical protein	NA	NA	NA	NA
WP_152430319.1\|1454914_1455856_-	homoserine O-succinyltransferase	NA	NA	NA	NA
WP_152430320.1\|1455982_1456360_+	AAA family ATPase	A0A218M380	Acidovorax_phage	1.7e-19	40.7
WP_152430321.1\|1456459_1458190_+	glutamate decarboxylase	NA	NA	NA	NA
WP_152430322.1\|1458341_1459862_-	tripartite tricarboxylate transporter permease	NA	NA	NA	NA
WP_152430323.1\|1459874_1460393_-	tripartite tricarboxylate transporter TctB family protein	NA	NA	NA	NA
WP_152430324.1\|1460541_1461516_-	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_152430325.1\|1462089_1463064_-	glycerophosphodiester phosphodiesterase	NA	NA	NA	NA
WP_152430326.1\|1463169_1463928_-	protein kinase	A0A1V0SBL5	Catovirus	2.6e-06	34.0
WP_152430327.1\|1463929_1467313_-	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_152430328.1\|1467315_1468521_-	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_152430329.1\|1468526_1469858_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_114785787.1\|1469878_1470361_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_152430330.1\|1470360_1471299_-	FHA domain-containing protein	NA	NA	NA	NA
WP_152430331.1\|1471303_1472026_-	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_152430332.1\|1472022_1473015_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_152430333.1\|1473011_1475561_-	MFS transporter	NA	NA	NA	NA
WP_152430334.1\|1475582_1478195_-	type VI secretion system ATPase TssH	K4FB40	Cronobacter_phage	5.4e-88	32.2
WP_152430335.1\|1478256_1479186_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_152430336.1\|1479203_1480955_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_152430337.1\|1480947_1481370_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_152430338.1\|1481369_1482764_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_152430339.1\|1482824_1484303_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_152430340.1\|1484302_1484806_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_152430341.1\|1484825_1485347_-	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_152430342.1\|1485380_1486757_-	type VI secretion system ImpA family N-terminal domain-containing protein	NA	NA	NA	NA
WP_152430343.1\|1487047_1487350_-	PAAR domain-containing protein	NA	NA	NA	NA
WP_152430344.1\|1487346_1487916_-	hypothetical protein	NA	NA	NA	NA
WP_152430345.1\|1487920_1489903_-	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	4.9e-25	26.1
WP_152431678.1\|1490076_1490856_-	hypothetical protein	NA	NA	NA	NA
WP_152430346.1\|1491090_1491798_-	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_152430347.1\|1491895_1492864_-\|transposase	IS30 family transposase	A0A2K9V2S9	Faecalibacterium_phage	8.9e-28	32.4

DBSCAN-SWA_4

2713135 : 2722499

Vibrio_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_114787819.1\|2713135_2713333_-	carbon storage regulator CsrA	A0A2I7RT00	Vibrio_phage	4.0e-12	61.7
WP_152431286.1\|2713425_2714613_-	aspartate kinase	A0A1X9I5D0	Streptococcus_phage	6.9e-06	25.4
WP_152431287.1\|2714789_2717372_-\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	3.8e-78	38.1
WP_152431288.1\|2717600_2718065_-	recombination regulator RecX	NA	NA	NA	NA
WP_152431735.1\|2718140_2719187_-	recombinase RecA	A0A2D1GPX2	Mycobacterium_phage	3.3e-113	61.9
WP_152431289.1\|2719364_2719850_-	nicotinamide-nucleotide amidase	B5TK85	Pseudomonas_phage	3.7e-27	48.3
WP_152431290.1\|2719934_2722499_+	DNA mismatch repair protein MutS	A0A1V0SC35	Catovirus	1.5e-42	23.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP045352

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP045351

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_CP045350

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection