CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP045411	Roseovarius sp. THAF8 plasmid pTHAF8_a, complete sequence	0 crisprs	NA	0	0	0	0
NZ_CP045412	Roseovarius sp. THAF8 plasmid pTHAF8_b, complete sequence	0 crisprs	csa3	0	0	0	0
NZ_CP045414	Roseovarius sp. THAF8 plasmid pTHAF8_d, complete sequence	0 crisprs	NA	0	0	0	0
NZ_CP045410	Roseovarius sp. THAF8 chromosome, complete genome	5 crisprs	cas3,DEDDh,csa3,WYL	0	2	2	0
NZ_CP045415	Roseovarius sp. THAF8 plasmid pTHAF8_e, complete sequence	0 crisprs	NA	0	0	0	0
NZ_CP045413	Roseovarius sp. THAF8 plasmid pTHAF8_c, complete sequence	0 crisprs	NA	0	0	0	0

1. NZ_CP045410

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP045410_1

• CRISPR_ID: NZ_CP045410_1
• CRISPR_location: 719483-719576
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP045410_1

Consensus_repeat	Method
AAGCCCGCGTAGGGTGGGTGAAAGCCCACGCGCC	CRISPRCasFinder

spacers of NZ_CP045410_1

>1.1|719517|26|NZ_CP045410|CRISPRCasFinder
ACGACGCCCGGAGGCGCGCCGCGAGC

CRISPR arrays and Neighbor proteins around NZ_CP045410_1

CRISPR arrays

The CRISPR arrays of NZ_CP045410_1

>merge|NZ_CP045410|1|719483-719576|CRISPRCasFinder
AAGCCCGCGTAGGGTGGGTGAAAGCCCACGCGCCACGACGCCCGGAGGCGCGCCGCGAGCAAGCCCGCGTAGGGTGGGTGAAAACCCACGCGCC

>NZ_CP045410|1|1|719483-719576|CRISPRCasFinder
AAGCCCGCGTAGGGTGGGTGAAAGCCCACGCGCC	ACGACGCCCGGAGGCGCGCCGCGAGC
AAGCCCGCGTAGGGTGGGTGAAAACCCACGCGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045410.1|WP_152495857.1|706143_707970_+|M24-family-metallopeptidase	unknown	unknown	gnl|CDD|238518
NZ_CP045410.1|WP_152495869.1|725815_726415_-|superoxide-dismutase	unknown	unknown	gnl|CDD|223678
NZ_CP045410.1|WP_152492061.1|719598_719820_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP045410.1|WP_152495868.1|724840_725737_-|EamA-family-transporter-RarD	unknown	unknown	gnl|CDD|225510
NZ_CP045410.1|WP_152495871.1|727390_730417_-|sarcosine-oxidase-subunit-alpha-family-protein	unknown	unknown	gnl|CDD|273584
NZ_CP045410.1|WP_152492072.1|703609_704014_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP045410.1|WP_152495866.1|720124_721942_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|227590
NZ_CP045410.1|WP_152492053.1|730413_730743_-|sarcosine-oxidase-subunit-delta	unknown	unknown	gnl|CDD|377276
NZ_CP045410.1|WP_152495859.1|708468_709458_-|fatty-acid-desaturase	unknown	unknown	gnl|CDD|239584
NZ_CP045410.1|WP_152495862.1|711864_713202_-|PQQ-binding-like-beta-propeller-repeat-protein	unknown	unknown	gnl|CDD|379140
NZ_CP045410.1|WP_152495856.1|704109_705984_+|cobaltochelatase-subunit-CobT	unknown	unknown	gnl|CDD|130712
NZ_CP045410.1|WP_152495861.1|710316_711780_-|ribosome-biogenesis-GTPase-Der	unknown	unknown	gnl|CDD|234628
NZ_CP045410.1|WP_152495858.1|708071_708413_+|DUF427-domain-containing-protein	unknown	unknown	gnl|CDD|377265
NZ_CP045410.1|WP_152495860.1|709610_710324_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP045410.1|WP_152492059.1|722109_722235_+|entericidin-A/B-family-lipoprotein	unknown	unknown	gnl|CDD|227797
NZ_CP045410.1|WP_152495867.1|724328_724880_+|TIGR00730-family-Rossman-fold-protein	unknown	unknown	gnl|CDD|129813
NZ_CP045410.1|WP_152495864.1|714166_715507_+|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl|CDD|273776
NZ_CP045410.1|WP_152495863.1|713251_713929_-|hypothetical-protein	unknown	unknown	gnl|CDD|226996
NZ_CP045410.1|WP_152498167.1|722348_723428_-|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl|CDD|236880
NZ_CP045410.1|WP_152495870.1|726828_727398_-|sarcosine-oxidase-subunit-gamma	unknown	unknown	gnl|CDD|226949

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP045410.1|WP_152495866.1|720124_721942_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|227590	COG5265, ATM1, ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones].	0
NZ_CP045410.1|WP_152495869.1|725815_726415_-|superoxide-dismutase	gnl|CDD|223678	COG0605, SodA, Superoxide dismutase [Inorganic ion transport and metabolism].	6.89551e-88
NZ_CP045410.1|WP_152492059.1|722109_722235_+|entericidin-A/B-family-lipoprotein	gnl|CDD|227797	COG5510, COG5510, Predicted small secreted protein [Function unknown].	9.00312e-05
NZ_CP045410.1|WP_152495868.1|724840_725737_-|EamA-family-transporter-RarD	gnl|CDD|225510	COG2962, RarD, Predicted permeases [General function prediction only].	1.0712e-75
NZ_CP045410.1|WP_152495871.1|727390_730417_-|sarcosine-oxidase-subunit-alpha-family-protein	gnl|CDD|273584	TIGR01372, sarcosine_oxidase_alpha_subunit, sarcosine oxidase, alpha subunit family, heterotetrameric form. This model describes the alpha subunit of a family of known and putative heterotetrameric sarcosine oxidases. Five operons of such oxidases are found in Mesorhizobium loti and three in Agrobacterium tumefaciens, a high enough copy number to suggest that not all members are share the same function. The model is designated as subfamily rather than equivalog for this reason.Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine to glycine. The reaction converts tetrahydrofolate to 5,10-methylene-tetrahydrofolate. The enzyme is known in monomeric and heterotetrameric (alpha,beta,gamma,delta) forms [Energy metabolism, Amino acids and amines].	0
NZ_CP045410.1|WP_152495857.1|706143_707970_+|M24-family-metallopeptidase	gnl|CDD|238518	cd01085, APP, X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide.	1.61069e-112
NZ_CP045410.1|WP_152492053.1|730413_730743_-|sarcosine-oxidase-subunit-delta	gnl|CDD|377276	pfam04267, SoxD, Sarcosine oxidase, delta subunit family. Sarcosine oxidase is a hetero-tetrameric enzyme that contains both covalently bound FMN and non-covalently bound FAD and NAD(+). This enzyme catalyzes the oxidative demethylation of sarcosine to yield glycine, H2O2, and 5,10-CH2-tetrahydrofolate (H4folate) in a reaction requiring H4folate and O2.	3.8639e-36
NZ_CP045410.1|WP_152495859.1|708468_709458_-|fatty-acid-desaturase	gnl|CDD|239584	cd03507, Delta12-FADS-like, The Delta12 Fatty Acid Desaturase (Delta12-FADS)-like CD includes the integral-membrane enzymes, delta-12 acyl-lipid desaturases, oleate 12-hydroxylases, omega3 and omega6 fatty acid desaturases, and other related proteins, found in a wide range of organisms including higher plants, green algae, diatoms, nematodes, fungi, and bacteria. The expression of these proteins appears to be temperature dependent: decreases in temperature result in increased levels of fatty acid desaturation within membrane lipids subsequently altering cell membrane fluidity. An important enzyme for the production of polyunsaturates in plants is the oleate delta-12 desaturase (Arabidopsis FAD2) of the endoplasmic reticulum. This enzyme accepts l-acyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate and requires NADH:cytochrome b oxidoreductase, cytochrome b, and oxygen for activity. FAD2 converts oleate(18:1) to linoleate (18:2) and is closely related to oleate 12-hydroxylase which catalyzes the hydroxylation of oleate to ricinoleate. Plastid-bound desaturases (Arabidopsis delta-12 desaturase (FAD6), omega-3 desaturase (FAD8), omega-6 desaturase (FAD6)), as well as, the cyanobacterial thylakoid-bound FADSs require oxygen, ferredoxin, and ferredoxin oxidoreductase for activity. As in higher plants, the cyanobacteria delta-12 (DesA) and omega-3 (DesB) FADSs desaturate oleate (18:1) to linoleate (18:2) and linoleate (18:2) to linolenate (18:3), respectively. Omega-3 (DesB/FAD8) and omega-6 (DesD/FAD6) desaturases catalyze reactions that introduce a double bond between carbons three and four, and carbons six and seven, respectively, from the methyl end of fatty acids. As with other members of this superfamily, this domain family has extensive hydrophobic regions that would be capable of spanning the membrane bilayer at least twice. Comparison of sequences also reveals the existence of three regions of conserved histidine cluster motifs that contain eight histidine residues: HXXXH, HXX(X)HH, and HXXHH. These histidine residues are reported to be catalytically essential and proposed to be the ligands for the iron atoms contained within the homologue, stearoyl CoA desaturase. Mutation of any one of four of these histidines in the Synechocystis delta-12 acyl-lipid desaturase resulted in complete inactivity.	3.09003e-61
NZ_CP045410.1|WP_152495862.1|711864_713202_-|PQQ-binding-like-beta-propeller-repeat-protein	gnl|CDD|379140	pfam13360, PQQ_2, PQQ-like domain. This domain contains several repeats of the PQQ repeat.	2.88154e-55
NZ_CP045410.1|WP_152495856.1|704109_705984_+|cobaltochelatase-subunit-CobT	gnl|CDD|130712	TIGR01651, CobT, cobaltochelatase, CobT subunit. This model describes Pseudomonas denitrificans CobT gene product, which is a cobalt chelatase subunit that functions in cobalamin biosynthesis. Cobalamin (vitamin B12) can be synthesized via several pathways, including an aerobic pathway (found in Pseudomonas denitrificans) and an anaerobic pathway (found in P. shermanii and Salmonella typhimurium). These pathways differ in the point of cobalt insertion during corrin ring formation. There are apparently a number of variations on these two pathways, where the major differences seem to be concerned with the process of ring contraction. Confusion regarding the functions of enzymes found in the aerobic vs. anaerobic pathways has arisen because nonhomologous genes in these different pathways were given the same gene symbols. Thus, cobT in the aerobic pathway (P. denitrificans) is not a homolog of cobT in the anaerobic pathway (S. typhimurium). It should be noted that E. coli synthesizes cobalamin only when it is supplied with the precursor cobinamide, which is a complex intermediate. Additionally, all E. coli cobalamin synthesis genes (cobU, cobS and cobT) were named after their Salmonella typhimurium homologs which function in the anaerobic cobalamin synthesis pathway. This model describes the aerobic cobalamin pathway Pseudomonas denitrificans CobT gene product, which is a cobalt chelatase subunit, with a MW ~70 kDa. The aerobic pathway cobalt chelatase is a heterotrimeric, ATP-dependent enzyme that catalyzes cobalt insertion during cobalamin biosynthesis. The other two subunits are the P. denitrificans CobS (TIGR01650) and CobN (pfam02514 CobN/Magnesium Chelatase) proteins. To avoid potential confusion with the nonhomologous Salmonella typhimurium/E.coli cobT gene product, the P. denitrificans gene symbol is not used in the name of this model. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin].	0
NZ_CP045410.1|WP_152495861.1|710316_711780_-|ribosome-biogenesis-GTPase-Der	gnl|CDD|234628	PRK00093, PRK00093, GTP-binding protein Der; Reviewed.	0
NZ_CP045410.1|WP_152495858.1|708071_708413_+|DUF427-domain-containing-protein	gnl|CDD|377265	pfam04248, NTP_transf_9, Domain of unknown function (DUF427). This domain contains a beta-tent fold.	2.85855e-42
NZ_CP045410.1|WP_152495867.1|724328_724880_+|TIGR00730-family-Rossman-fold-protein	gnl|CDD|129813	TIGR00730, LOG_family_protein_YJL055W, TIGR00730 family protein. This model represents one branch of a subfamily of proteins of unknown function. Both PSI-BLAST and weak hits by this model show a low level of similarity to and suggest an evolutionary relationship of the subfamily to the DprA/Smf family of DNA-processing proteins involved in chromosomal transformation with foreign DNA. Both Aquifex aeolicus and Mycobacterium leprae have one member in each of two branches of this subfamily, suggesting that the branches may have distinct functions. [Hypothetical proteins, Conserved].	4.95899e-52
NZ_CP045410.1|WP_152495864.1|714166_715507_+|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl|CDD|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	1.22193e-34
NZ_CP045410.1|WP_152495863.1|713251_713929_-|hypothetical-protein	gnl|CDD|226996	COG4649, COG4649, Uncharacterized protein conserved in bacteria [Function unknown].	1.34865e-12
NZ_CP045410.1|WP_152498167.1|722348_723428_-|LysM-peptidoglycan-binding-domain-containing-protein	gnl|CDD|236880	PRK11198, PRK11198, LysM domain/BON superfamily protein; Provisional.	9.69213e-15
NZ_CP045410.1|WP_152495870.1|726828_727398_-|sarcosine-oxidase-subunit-gamma	gnl|CDD|226949	COG4583, COG4583, Sarcosine oxidase gamma subunit [Amino acid transport and metabolism].	1.17004e-21

Protein sequences

>NZ_CP045410.1|WP_152495864.1|714166_715507_+|efflux-RND-transporter-periplasmic-adaptor-subunit
MRLFPIFAAILVCAAIYALVMERDSIAALFAPVEDTELAEAVAPDTDQGDDPLAETPEEREGTVGVVALRSTARTIDTAVTVRGQTEADRQVELRAETPGQIVSEPIRKGAFVEEDQTLCQIDPGTREANLAEALARLAEARSRIPEAEAAVPEAAARVEESRARLVEARAVLSEAEINANAADKLSTDGFASQTRVAQTKAAVEGAKAQITSAEAALKAAESGQETAAAGIEAARSGVESAQAAVASARKEIERLTIKAPFSGLLESDTAELGSLLQAGSLCATVIQLDPIMLVGYIPETEIAKVSAGAPATARLASGGTVEGEVTFISRAADPTTRTFRVDIRVPNEDLALRDGQTAEIRIESEGVKAHLLPQSALTLDDDGALGVRIVSPDKTAQFKPVTLLRDSPTGVFVAGLEETSDVIILGQEFVADGVPVEPAFRETIQ
>NZ_CP045410.1|WP_152495863.1|713251_713929_-|hypothetical-protein
MSQSDSFIDEVTEEVRRDRLYRNFKRYGWIGILAVLLLVAGAAFNEWRKAQERAEAEALGDAIIAALGEEDAAARNAALDAIQPETGGARAIVGLLAAGEGGADNAPQTADQLLRLADSADVPLVYRQIATLKAVALPGSGLSPEDKRARLEGMAASGGIVRLLAEEQLALVDLEAGDRDAALERLRGLYESAEATAGLRRRVEQLIVALDGDIEEEPVGETDGN
>NZ_CP045410.1|WP_152495862.1|711864_713202_-|PQQ-binding-like-beta-propeller-repeat-protein
MAVKTLAGVIGLSALCLVAACAKKENILTGERQEISDILQTEPGDSALAPQAVSGAVPPLALPAARSNASWAQSISNARTRVAHPALRGTPQLAWTANIGQGDSRKSRITADPVVGGGRVYTLDSRAQVTAVSTSGQVIWTRDLVPANDGAIDGSGGGLAYDNGQLFVSSGFGLLTAIDAATGQVQWQQNLRATGSGSPTVAGDLVYAVAGDELAWALDRTDGRIAWQLEATSDIRNVLGAPSPAVSDKYVVFGFGSGEVQGAFLKGGLRRWTTQIAGKRRGYSSGIIEDVTGEPVIEGNTIFAGNHSGRTVALNLGNGERLWTAADGPLYRVWPAGDSIFMVSDRNELLRLAQSDGRRLWGVKLPFFTKSKPKKQARIFAHHGPIIAGGRLIIASSDGLMRFFDPTNGASLGQVQMPGGATTNPVVAGNTLYVVSSKGQLMAFR
>NZ_CP045410.1|WP_152495861.1|710316_711780_-|ribosome-biogenesis-GTPase-Der
MSFTLAIVGRPNVGKSTLFNRLVGKRLALVDDQPGVTRDLREGDARLADLRFTVIDTAGLEDATDDSLEGRMRKLTERAVDMADVCLFLIDARAGVTALDEMFAEILRKRADHVFVAANKSEGSAADAGVLEAYSLGLGEPIRLSAEHGEGMHDLYTALLPLADGYAERAEAEAPEVDVAVDEDGEADPEGVRKPTKARPLQVAVVGRPNAGKSTLINKILGEDRLLTGPEAGITRDAISVKMDWDGLPMRIFDTAGMRKKAKVQEKLEKLSVSDGLRAVKFAEVVVVLLDAAIPFEQQDLRIADLAEREGRAVVVAVNKWDIEDDKQGKLRDLREAFERLLPQLRGAPLVTVSAKTGKGLDRLHAAIEKAYDVWNRRVSTARLNRWLTGVLEAHPPPAPGGRRIKLRYMTQAKTRPPGFVVMCSHPDKMPASYSRYLVNGLREDFDMPGTPIRLTLRSQSDKNPYKAKKKAGPSKLRKHIKGRGPS
>NZ_CP045410.1|WP_152495860.1|709610_710324_+|hypothetical-protein
MHKVKAIFALVAAILFAMSPVYSSGFNGFSAGQFPIPQDTPPVQPAGYAFSIWGLIYIWLLAGALFGLINRYDDPAWDAMRWPYIVSLVLGSAWIPVANISPAWATALIWLMWGTAALALMRAGTRDRIWLRTPIALYTGWLTAASCVALGLLLPGYGVLSQSTAALLMIALALALSAAMLALRPDTPEFAAAVVWALVGIAVTNADPVNWPVLALSGAGVVALALLVLRGRPDRLS
>NZ_CP045410.1|WP_152495859.1|708468_709458_-|fatty-acid-desaturase
MTIRDYLRDYAQKSDGMGALSLGATFAVYGAALGLGAWAWPAWWAVLPCVVVLSFASVRLYVLQHDCGHYSLFATRWANDVAGHVLSVFSLTPYRVMQFNHNQHHAYLGNLEHRETTEVYTMTLQEWRDAGAWTRVWYRIYRNPVVMLSLGGIYAYFIAYRWPVNTMKVGPWGVVAHNIAVAAYVAAVWALLGVPGLVVLGASAVLAGVIGVFLVYLQHNFEDTYWDRKPDLDFRKATLEGSSSLDLGHWWDIGTGNIAYHDLHHYNPQIPSYNLRRAQKNLPDDLRVHDEIRWREALASFRLKLWDEESGKLVPFPRRRSPREAAVGA
>NZ_CP045410.1|WP_152495858.1|708071_708413_+|DUF427-domain-containing-protein
MAKITIHKADGTWTVRAGGAVLVESRNALVLAEEGLNDVIYFPREDIAMAFLDESDHRTTCPHKGEASHFSIVTKSKTLENAAWSYEDPKPDVARIKDHLAFYSSDDVTVEQV
>NZ_CP045410.1|WP_152495857.1|706143_707970_+|M24-family-metallopeptidase
MTDLPDTVFQSFTETSSPEQGPPRLKLLRAELEREGVDGFMIPRADAHQGEYVAAGDERLAWLTGFTGSAGFCIVLQDIAGVFIDGRYRGQVRAQVDTDHFTPVDWPETRPAGWLKAHLPNGGTVAYDPWLYTPEQITAIEDGLKDTRITLTPTENLLDRTWPDRPAPPTGAVRVYPDDLAGKSHADKRRELAETLAEDGHRAAILTLPDSIAWLLNIRGSDIPRNPIPHAFAILHDDAKVDLYIDPAKLDDTVRTHLVEDITLALPQDFEPAISALSGPVRLDHGSVPLRIVTLLEDAGTDTAYAGDPCILPKACKTDAEIAATTKAHLRDAAAMCTFLAWFDAQAPGTITEIDVVKKLEACRRDTGALLDISFDTIAGSGPHGALPHYRVSEATDRTLQDGDLLVLDSGGQYQDGTTDITRTLAIGQPGDTERAAFTRVLQGMIAMSRARWPKGLAGRDLDAIARYPLWLAGQDYDHGTGHGVGVHLCVHEGPQRLSRASTEPLQPGMILSNEPGYYREGAFGIRIENLVVVTPAPALPDGDDTRQMLHFTTLNYVPIDRRLIDAAALSDPERDWLNAYHATCRDRIGPRLDDASRDWLTGATAPL
>NZ_CP045410.1|WP_152495856.1|704109_705984_+|cobaltochelatase-subunit-CobT
MAHSDNPADPFKKALAEATKVLADDPDLNVSYSVDPAGVSGDSMRLPQISRRMTKDEVLQARGTADALALRHKYHDAGTHTRYCPPGDMARDLYEAMETARCEAMGARHMPGTAGNIDAKIGAEARRRGYDQITDAAEAPLANAAGYLIRHLATGRDLPDGARNVMELWKGFIEEQAGGTLEDLQSKLSDQSEFARFARQIIDDLGYGDQLGDDPDALDDEDETEAEADQEEEEQPDSTGEDDSDEAEADADPEQSQDQQQDEAQAQVSMDDMADQEQGDETEMPEGEAPLDPPPPLPISDADPNYAVYNSAFDEEIHAEDLAEPIELERLRAFLDQQLEPLKGAVSRLANKLQRRLQAQQNRSWEFDREEGILDAGRLARVVANPTTPLSFKVEKDTEFRDTVVTLLLDNSGSMRGRPISIAAICADVLARTLERCNVKVEILGFTTRAWKGGQSRESWLNEGRPQLPGRLNDLRHIIYKSADAPMRRTRSNLGLMMKEGLLKENIDGEALEWAHRRLAGRREARKILMVISDGAPVDDSTLSVNPANYLEKHLRDVIAMVERRKQVELLAIGIGHDVTRYYNRAVTITDADQLAGVMTEQLAALFDSDPRARARVMGMKRAS
>NZ_CP045410.1|WP_152492072.1|703609_704014_+|hypothetical-protein
MTNEKHTLAAAAFLITSTLAAPSNALSLAEQAEAFATCAGRYSAMATRQSATHNPDSDATRALQSSFESLLEAMLPHAAEAGIDPRRARSWQASGWSEMAQLMRLQQRSADATHADRASRDMHRRLSTCRQLIL
>NZ_CP045410.1|WP_152492061.1|719598_719820_-|hypothetical-protein
MFRGTILYFSDDGGVAHIWCAKAGNPLFRARASDFPDLWPDLRVGMVVTVVGSTGTDEAQTVVTLEIAPQDEG
>NZ_CP045410.1|WP_152495866.1|720124_721942_-|ATP-binding-cassette-domain-containing-protein
MRRRPTTATEMPDNALQVIRRVAPYLWPEGQSWAKRRVVLALMALVLAKVVAVGTPFFYKAAVDSLSGEGQEAAWMLGAGAIGLTVAYGMARLMNVGFQQLRDAIFAPVAQRGLRRLALETFQHIHQMSMRFHMTRKTGGLSRIIERGVKSVEFLLRFLVFSVGPLILELLMIGVVLWTLFDFSYLAVVMGVIATYAVFTFKVTEWRVKLRRRMNEQDTDANQKAIDSLLNFETVKYFGAEGREAARYDRAMEGYESAALQTSYSLAFLNVGQSFLITGGLVAVMVMAAMGVQSGALTVGDFVMVNAYMIQITMPLNFLGTVYREIRQSLVDMAQMFDLLEQTPDVTDGSDAKGLKIEGGSVRFREVSFGYDPERPILHDVSLSVAAGETVALVGPSGSGKSTIGRLLFRFYDVSGGALEIDGQDVRGVTQESLHAAIGVVPQDTVLFNDTIGYNIAYGRDGATQDEIEAAAKAAQIHEFIARLPKGYETQVGERGLKLSGGEKQRVGIARTLLKDPPILLLDEATSALDTETEREIQDALRRAGEGRTVITIAHRLSTVADADRIVVLEDGRIVEEGTHAELLAREGRYAGLWARQASERERAA
>NZ_CP045410.1|WP_152492059.1|722109_722235_+|entericidin-A/B-family-lipoprotein
MRFIAALTALFALAACETTEGFGRDLSNLGDNIEEEAEEND
>NZ_CP045410.1|WP_152498167.1|722348_723428_-|LysM-peptidoglycan-binding-domain-containing-protein
MTKERAAEEAAGGVETAALSDPAEPAQEDQQGVPESGTEGSDVARTAAPEQVDGGGSDGGTESVGAAGEGAAADEASTQQATARDAGDDAGPSAAGTGRDEGASAQADTEQAATGGGAGDAETARATGGAATGQGTDAASGGQSADSATDSATDSAADRVGGGTGDDATDQPDPAPGAAVLMSDADGVRVIQPAPGDASPEVMAVVALDAISYSDTGAVELSGRGASDGFVRVYLDNTPVTTSRIAADGSWQSDLPEVDTGVYTLRIDEVDADGNVTSRVETPFKREDEALLADATQAGKLVQAVTVQPGYTLWGISRRNYGEGIEYVRIFEANRDRIRDPDLIYPGQVFTIPDQVAVQ
>NZ_CP045410.1|WP_152495867.1|724328_724880_+|TIGR00730-family-Rossman-fold-protein
MPKRSVCVFCGSRKGRNPAYEAAAKALGTALAEHDMRLVYGAGDVGLMGAVARAAQAAGGETFGVIPDHLVKWEVGKTDLTRYIVTETMHERKKVMFMNCDAVVVLPGGAGSLDEYFEVLTWRQIGLHEKPVFLLDTEGYWTRLIQLIDHVIDEGFADASLRDYTQVVDTVQDLMDGLGATGR
>NZ_CP045410.1|WP_152495868.1|724840_725737_-|EamA-family-transporter-RarD
MTETAKGVAAIVLACTIWGLSGLFYKLLAGLPVLDVLAHRTIWGAVFFLLILGVQGRVAVPFRALGAGRTLRVLAAASLLIGFNWMLFVWAIKSDQALEASLGYYIFPLVVVLFGLMFFGERLGRGETLAVLLAALAVIVLTAGLGVAPWIALGIALSFGAYGAVKKRLDMGPVVSVTAESLLLVGPALGWLAWQAAQGGAVLGGSWPLALTLMLAGPMTATPLILFSYGARRIDLASVGVLSYLNPSLQFAVAVVIFAEPFTGWHMIAFAMIWGALALYSVARWRYRPVAPRPSIRS
>NZ_CP045410.1|WP_152495869.1|725815_726415_-|superoxide-dismutase
MAFELPDLPYAHDALASKGMSKETLEYHHDIHHNAYVTNGNKAIEGTEWDGKSMEEIIKGTYDPNAVAQSGIFNNISQLWNHNQFWEMMTPEDSKMPGELEKAINDSFGSVDKFKDEFKAAGGGQFGSGWAWLVKDTDGSLKVTKTENGVNPVCFNQTALLGCDVWEHSYYIDFRNKRPDYLANFLDNLVNWENVASRM
>NZ_CP045410.1|WP_152495870.1|726828_727398_-|sarcosine-oxidase-subunit-gamma
MSKAVSALQGAVYQGYVEVREMGLQGMITLRGDLSSAKMKKAVKDACGVDLPGQREIAVAGDKGAAWMSPDELLLMVPYEGVGDALAAVEKALSGEHFLAVNVSDARAVFQVQGASAREIIAKLCPVDMAPGAFEPGQIRRTRMAQIAAAFWMVDAETIRVVCFRSVAEYAFNLLKDAAEPGGETGLFA
>NZ_CP045410.1|WP_152495871.1|727390_730417_-|sarcosine-oxidase-subunit-alpha-family-protein
MSTRLANGGRLVNKAHAMEFTFNGKRLKGYEGDTLASALLANDQMLVGRSFKYHRPRGIVASGGEEPNGLVNMGRGESFEPNQRVTTTELFDGLEATSQNHWPSLEFDVGAINAKFSRFLPAGFYYKMFIHPRPLWKHVYEPFIRQSAGLGKAPKDKDGDKYEHLYAFYDVVVIGGGVAGLMAARAAGAAGAKVLLMEQTAAWGGRTPVDGPLYSATVNDGPVDKFVDELVAELDEMSNVEMRLRMMGAGVYDHGYLLGYERVNDHTPKAKGPRHRLWRIRAGQIVTATGAIERPLSFAGNDVPGVMLASAVRDYVVNYGVSVGDRTVVVTNNDDAYLTALALKAAGLDVPAIIDARAAGAGVLAEKAKAAGIRVETGKGIAKVRGGKRVTGVGICAQAGEGSALEEIACDAVAMSGGWSPVVHLWSHCGGKLLWDETQAMFRPDPEKAPTGAAGEAYVSTAGTASGELDLGAVLADAEEAGRAAAKAVGKTPKKAEKPTAEGVQCNVIQPIWMMPQGANVKLRMKSWLDYQNDVKVSDVQLAAREGYESVEHAKRYTTLGMATDQGKLSNINGLAILSDALNQPIPQTGTTTFRPPYTPISMASIAGEARGEIFQPLRKTPMHDWHEANGAYWEPVGHWRRPYTFRQNPGEEISAAVKREINQTRGSLGLLDASTLGKLIVKGPDAGRFLDMLYTNMMSTLKPGRCRYGLMCSENGFLMDDGVVARLDDDTFLCHTTTGGADSIHAHMEEWLQTEWWDWKVYVANVTEQYAQIGVVGPKARKTLEKLTDADLSAEALPFMAWQDIDFGDVKARVFRISFSGELSYEIAVPASQGRAFWDQLLEAGKEFGVMPYGTEGLHVMRAEKGFIMIGDETDGTVIPQDLGMQWAISKKKDDYIGKRAQQRSHMADPERWQLVGLQTVDGSVLPDGAYCVAEGDNANGQRNVQGRVTSTYYSPTLDRGIAMGLVKYGTDRMDEVIEFAKVDGTTVPTRIVSAVFYDPEGEKQNV
>NZ_CP045410.1|WP_152492053.1|730413_730743_-|sarcosine-oxidase-subunit-delta
MLILECPYCGVKGEETEFAGGGEAHLKRFGPDSSDDDFHAYLFKRENPKGVHLERWRHTNGCGKWFHAARNTVTLEVYGTYSAQTTEPPKDIKDKISAKVPGWSWREFS

Crispr_ID: NZ_CP045410_2

• CRISPR_ID: NZ_CP045410_2
• CRISPR_location: 1945972-1946046
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP045410_2

Consensus_repeat	Method
CGTAGGGTGGGTGAAAACCCACCAC	CRISPRCasFinder

spacers of NZ_CP045410_2

>2.1|1945997|25|NZ_CP045410|CRISPRCasFinder
GCCCCTCACCCCTCGCGCAACATCG

CRISPR arrays and Neighbor proteins around NZ_CP045410_2

CRISPR arrays

The CRISPR arrays of NZ_CP045410_2

>merge|NZ_CP045410|2|1945972-1946046|CRISPRCasFinder
CGTAGGGTGGGTGAAAACCCACCACGCCCCTCACCCCTCGCGCAACATCGCGTAGGGTGGGTGAAAACCCACGCA

>NZ_CP045410|2|2|1945972-1946046|CRISPRCasFinder
CGTAGGGTGGGTGAAAACCCACCAC	GCCCCTCACCCCTCGCGCAACATCG
CGTAGGGTGGGTGAAAACCCACGCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045410.1|WP_152496715.1|1938374_1940567_-|PBP1A-family-penicillin-binding-protein	unknown	unknown	gnl|CDD|223815
NZ_CP045410.1|WP_172978852.1|1953716_1954394_-|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223736
NZ_CP045410.1|WP_152496717.1|1942745_1943642_+|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl|CDD|376806
NZ_CP045410.1|WP_152496713.1|1935864_1936623_+|VacJ-family-lipoprotein	unknown	unknown	gnl|CDD|377309
NZ_CP045410.1|WP_152496722.1|1947467_1948952_+|AMP-nucleosidase	unknown	unknown	gnl|CDD|236222
NZ_CP045410.1|WP_152496716.1|1941276_1942620_+|ammonium-transporter	unknown	unknown	gnl|CDD|274697
NZ_CP045410.1|WP_152496723.1|1951544_1952234_+|ZinT/AdcA-family-metal-binding-protein	unknown	unknown	gnl|CDD|370371
NZ_CP045410.1|WP_152496712.1|1933921_1935658_-|type-I-secretion-system-permease/ATPase	unknown	unknown	gnl|CDD|226969
NZ_CP045410.1|WP_152490975.1|1936624_1937218_+|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|377516
NZ_CP045410.1|WP_152490972.1|1940909_1941248_+|P-II-family-nitrogen-regulator	unknown	unknown	gnl|CDD|366157
NZ_CP045410.1|WP_152490963.1|1949633_1951178_+|amino-acid-carrier-protein	unknown	unknown	gnl|CDD|376500
NZ_CP045410.1|WP_152490964.1|1949157_1949592_+|universal-stress-protein	unknown	unknown	gnl|CDD|366180
NZ_CP045410.1|WP_152496721.1|1946929_1947373_-|VOC-family-protein	unknown	unknown	gnl|CDD|319910
NZ_CP045410.1|WP_152496725.1|1954540_1955386_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|319973
NZ_CP045410.1|WP_152496718.1|1943703_1944666_+|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta	unknown	unknown	gnl|CDD|235547
NZ_CP045410.1|WP_152496726.1|1955382_1956381_+|ArsJ-associated-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl|CDD|169599
NZ_CP045410.1|WP_152496714.1|1937349_1938336_+|YihY-family-inner-membrane-protein	unknown	unknown	gnl|CDD|224214
NZ_CP045410.1|WP_152496720.1|1946053_1946920_-|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|187576
NZ_CP045410.1|WP_152496719.1|1944662_1945937_+|bifunctional-folylpolyglutamate-synthase/dihydrofolate-synthase	unknown	unknown	gnl|CDD|223362
NZ_CP045410.1|WP_152490961.1|1952534_1953605_-|PAS-domain-containing-protein	unknown	unknown	gnl|CDD|237427

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP045410.1|WP_152496715.1|1938374_1940567_-|PBP1A-family-penicillin-binding-protein	gnl|CDD|223815	COG0744, MrcB, Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane].	0
NZ_CP045410.1|WP_172978852.1|1953716_1954394_-|Crp/Fnr-family-transcriptional-regulator	gnl|CDD|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	2.11432e-20
NZ_CP045410.1|WP_152496717.1|1942745_1943642_+|CPBP-family-intramembrane-metalloprotease	gnl|CDD|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	2.24839e-10
NZ_CP045410.1|WP_152496713.1|1935864_1936623_+|VacJ-family-lipoprotein	gnl|CDD|377309	pfam04333, MlaA, MlaA lipoprotein. MlaA is a component of the Mla pathway, an ABC transport system that functions to maintain the asymmetry of the outer membrane. MlaA is required for the intercellular spreading of Shigella flexneri. It is attached to the outer membrane by a lipid anchor.	1.0585e-75
NZ_CP045410.1|WP_152496722.1|1947467_1948952_+|AMP-nucleosidase	gnl|CDD|236222	PRK08292, PRK08292, AMP nucleosidase; Provisional.	0
NZ_CP045410.1|WP_152496716.1|1941276_1942620_+|ammonium-transporter	gnl|CDD|274697	TIGR03644, marine_trans_1, probable ammonium transporter, marine subtype. Members of this protein family are well conserved subclass of putative ammonimum transporters, belonging to the much broader set of ammonium/methylammonium transporter described by TIGR00836. Species with this transporter tend to be marine bacteria. Partial phylogenetic profiling (PPP) picks a member of this protein family as the single best-scoring protein vs. a reference profile for the marine environment Genome Property for a large number of different query genomes. This finding by PPP suggests that this transporter family represents an important adaptation to the marine environment.	0
NZ_CP045410.1|WP_152496723.1|1951544_1952234_+|ZinT/AdcA-family-metal-binding-protein	gnl|CDD|370371	pfam09223, ZinT, ZinT (YodA) periplasmic lipocalin-like zinc-recruitment. ZinT plays a critical role in recruiting periplasmic zinc to the bacterial zinc-uptake complex ZnuABC, consisting of families pfam01297,pfam00950, pfam00005, regulated by the transcription-regulator FUR, pfam01475. ZinT acts as a Zn2+-buffering protein that delivers Zn2+ to ZnuA (TroA), pfam01297. Members of this family of prokaryotic domains were first identified as part of the response of bacteria to a challenge with the toxic heavy metal cadmium. They are able to bind to cadmium, and ensure its subsequent elimination.	1.96747e-111
NZ_CP045410.1|WP_152496712.1|1933921_1935658_-|type-I-secretion-system-permease/ATPase	gnl|CDD|226969	COG4618, ArpD, ABC-type protease/lipase transport system, ATPase and permease components [General function prediction only].	0
NZ_CP045410.1|WP_152490975.1|1936624_1937218_+|ABC-transporter-substrate-binding-protein	gnl|CDD|377516	pfam05494, MlaC, MlaC protein. MlaC is a component of the Mla pathway, an ABC transport system that functions to maintain the asymmetry of the outer membrane. This family of proteins is involved in toluene tolerance, which is mediated by increased cell membrane rigidity resulting from changes in fatty acid and phospholipid compositions, exclusion of toluene from the cell membrane, and removal of intracellular toluene by degradation. Many proteins are involved in these processes.	4.47118e-34
NZ_CP045410.1|WP_152490972.1|1940909_1941248_+|P-II-family-nitrogen-regulator	gnl|CDD|366157	pfam00543, P-II, Nitrogen regulatory protein P-II. P-II modulates the activity of glutamine synthetase.	6.45286e-50
NZ_CP045410.1|WP_152490963.1|1949633_1951178_+|amino-acid-carrier-protein	gnl|CDD|376500	pfam01235, Na_Ala_symp, Sodium:alanine symporter family.	4.58204e-155
NZ_CP045410.1|WP_152490964.1|1949157_1949592_+|universal-stress-protein	gnl|CDD|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	9.15934e-30
NZ_CP045410.1|WP_152496721.1|1946929_1947373_-|VOC-family-protein	gnl|CDD|319910	cd07246, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	4.07443e-09
NZ_CP045410.1|WP_152496725.1|1954540_1955386_+|helix-turn-helix-domain-containing-protein	gnl|CDD|319973	cd16345, LMWP_ArsC, Arsenate reductase of the LMWP family. Arsenate reductase plays an important role in the reduction of intracellular arsenate to arsenite, an important step in arsenic detoxification. The reduction involves three different thiolate nucleophiles. In arsenate reductases of the LMWP family, reduction can be coupled with thioredoxin (Trx)/thioredoxin reductase (TrxR) or glutathione (GSH)/glutaredoxin (Grx).	1.00915e-56
NZ_CP045410.1|WP_152496718.1|1943703_1944666_+|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta	gnl|CDD|235547	PRK05654, PRK05654, acetyl-CoA carboxylase carboxyltransferase subunit beta.	6.87155e-173
NZ_CP045410.1|WP_152496726.1|1955382_1956381_+|ArsJ-associated-glyceraldehyde-3-phosphate-dehydrogenase	gnl|CDD|169599	PRK08955, PRK08955, glyceraldehyde-3-phosphate dehydrogenase; Validated.	0
NZ_CP045410.1|WP_152496714.1|1937349_1938336_+|YihY-family-inner-membrane-protein	gnl|CDD|224214	COG1295, Rbn, Ribonuclease BN family enzyme [Replication, recombination, and repair].	8.60544e-62
NZ_CP045410.1|WP_152496720.1|1946053_1946920_-|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|187576	cd05266, SDR_a4, atypical (a) SDRs, subgroup 4. Atypical SDRs in this subgroup are poorly defined, one member is identified as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is related to, but is different from, the archetypical SDRs, GXGXXG. This subgroup also lacks most of the characteristic active site residues of the SDRs; however, the upstream Ser is present at the usual place, and some potential catalytic residues are present in place of the usual YXXXK active site motif. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.3019e-83
NZ_CP045410.1|WP_152496719.1|1944662_1945937_+|bifunctional-folylpolyglutamate-synthase/dihydrofolate-synthase	gnl|CDD|223362	COG0285, FolC, Folylpolyglutamate synthase [Coenzyme metabolism].	2.58951e-133
NZ_CP045410.1|WP_152490961.1|1952534_1953605_-|PAS-domain-containing-protein	gnl|CDD|237427	PRK13559, PRK13559, hypothetical protein; Provisional.	1.07742e-48

Protein sequences

>NZ_CP045410.1|WP_152496719.1|1944662_1945937_+|bifunctional-folylpolyglutamate-synthase/dihydrofolate-synthase
MTAPTSDVILDRMMALHPKIIDLTLDRVWRLLEALGNPQNDLPPVIHIAGTNGKGSTLAMIRAGIEGAGKTAHAYTSPHLARFHERIRLAGELITEPHLTEVLDECYAANGGEPITYFEITTCAAILAMSRTPADYTLLEVGLGGRLDATNVVATPALTIITPVSMDHEQYLGDTLAKIATEKAGILKRGVTCVVGPQDEEGMDAIEAAAQRTHSPLRAHGQHWHVTTERGRLIYQDETGLRDLPLPNLPGAHQYENAGAALAALRHLHLGDTALEAAVTHAHWPARMQRLSTGPLAEAAPQAELWLDGGHNPAAGRALAAHLASLPPRPTHLVCGMLNTKDISGYLSPLAGVAQSLTAISIPGEANTLPADATATAAANAGLPSGTAASARAAIEDIAAKDPTARILICGSLYLAGAILRENG
>NZ_CP045410.1|WP_152496718.1|1943703_1944666_+|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta
MNWITNYVRPRINSIFSRREIPENLWTKCDECGTMLFHRELRENLNVCTSCGHHMAITPRDRFTALFDGGTFAQVSVPQPTADPLQFRDQKKYPDRLRAAQKATGETEAMLVASGEIGRTPIVAAAQDFSFMAGSMGMYVGNAIIAAAEEAVKLKRPLVLFSAAGGARMQEGILSLMQMPRTTVAVQMLKEAGLPYIVVLTHPTTGGVTASYAMLGDVHIAEPGALICFAGPRVIEQTIREKLPEGFQRAEYLLDHGMLDRVTPRGEMRTELITILRMLLNLPPAVTADLPAPELPAEEESQHAAQPDTAEEQSADDTDK
>NZ_CP045410.1|WP_152496717.1|1942745_1943642_+|CPBP-family-intramembrane-metalloprotease
MSDAYRPFEALVAPARRTASLVRLVLGGVMLAVLFLSTIFAASTLLNLVLPGAPLDETAAALANGGTPYGVLANLYIFGFIILALAITGRAVHDRSLPSFVGDWRRARQHFGRVCLYMVGLHLALSILLPATPDLTPEANLAPSSWLAFLPLALPAILVQTGAEELVFRGYLQSQLAARFANPRIWIIVPAVLFGLLHYDPAINGDATWLIVGWATLFGIAAADLTARTGTIGAALGLHFVNNFFAILVAAPAGNFDGLALYTYPFAVGDTDALWVWAPLDLMLLLVSWLTARLALRV
>NZ_CP045410.1|WP_152496716.1|1941276_1942620_+|ammonium-transporter
MKRIIHLGLAATAIAVLPQFGFAQEAAEAAEAEAAAPGFDEIGPYIMTTLLFCMAGFLVFFMAAGFAMLEGGLVRSKNVTMQMTKNIALFSIAAIMYWLVGFNTMYPGDFNGYFAIGGQTVLDPVGVAAADAALDYASIGSDFFFQLVFVAATASIVSGALAERIKLWPFLIFVVILTGFMYPISGSWKWGAGWLDAMGFQDFAGSTVVHSVGGWAALAGAIVLGPRLGKYGKDGKVHPMPGSNLALATLGTFILWLGWFGFNGGSQLAMGTVGDVSDVSRIFANTNMAAASGAVTALILSQVMYKKPDLTMVLNGALAGLVSITAEPLAPTLFGALWIGAVGGVIVVLTIPMLDKLKIDDVVGAVPVHLFAGIWGTIAVIFYNGDANLMTQLTGIVAYGVFTFVASLIIWFILKAVMGIRVGEEEEIAGLDMSELGMEAYPEFSKG
>NZ_CP045410.1|WP_152490972.1|1940909_1941248_+|P-II-family-nitrogen-regulator
MKLIIATIKPFKLEDVREALTGIGVRGMMVTEIKGFGSQSGHTEIYRGAEYAVNFVPKIKLEIAVTAGMVDQVVETIATTARTGKIGDGKIFVLDIGQAMRVRTGETNDDAL
>NZ_CP045410.1|WP_152496715.1|1938374_1940567_-|PBP1A-family-penicillin-binding-protein
MGNQGRKAPRLVADRRYGKTTKTPAKSRAKTAARKPAKPARTRRKSGGGSGGGRGPVAWIKRLFRWILRLFWVVTWRVTAVALLVTALAVAYVYAGLPDVRALLDGRARGSVTMLDREGDVFAWRGDQFGGVVTADTVSPDLRNAVLATEDKRFYRHFGLSPRGIASAIRINLSEGRGPLSGHGGSTITQQTAKLLCLGVEYDESEWESEAEYVRDCRRGSLGRKAKEAVYAMAMEAKYSKNEILSIYLNRAYFGGGAFGVEAAAQRYFGVSAREVNAAQSAMLAGLLTAPTRLAPTTNLERSQNRAATVLRLMNEQGYLTDAEAQAAQDNPATLSEAAAAQAGGYFADWVMDSGPELFTRDTTEDVIIQTTLDQRMQRAAEEALTHVFENKVSDGSEAQAAIVVMSADGAVRAMVGGRKSRVTGAFNRATMAKRQTGSAFKPFVYATALELGYEPTSMVVDEPYCRNIAGSGQWCPENYDKKFHGRVPLIRALAQSYNIPAVKVAESVGLDLVRRVASDFGIDNDLAEGPALALGTSESTLLEMTGAYAGILNGGSSVTPYGLVELKLLGDDDPLMRKSGGIGERVIQQEAAQKLTGMMYEVVQSGTGARAKLPDRQAAGKTGTTQAARDAWFLGFTADYVTGVWMGYDDNTPLKGVTGGGLPADIWRETMVRVNEGVPVSDLPMIFVQPEPEPQVQQQWPQQQQPQGDRDNTINRMLEELLEGTGNRR
>NZ_CP045410.1|WP_152496714.1|1937349_1938336_+|YihY-family-inner-membrane-protein
MPDKGRGHTADHPHHISRHGWWDVVLRLKDGIASDHMSVVSAGVAFFGLLAIFPAVVALISIAGFLLNPQDVANNLEQIIAILPENAAAIIQDQIMKVTGGDEAATGLAALLGLLLALYGATKGMMTLMEGMNIAYGEKEKRGFVRLHATGLALTLFIIVGVLSALGLMIVLPAVIGYLGLSETLETTILWLQWPVLGCLAVLGLGVLYRFGPSRRNARWRWITPGAVVAMILWLAGTVAFSVYTQNFASYNETYGTLGGAIILLTWLWLSSFIVLAGAKLNAELEHQTRRDTTTGPERPEGERGAVKSDTFPDTGTQATSHAAPGKD
>NZ_CP045410.1|WP_152490975.1|1936624_1937218_+|ABC-transporter-substrate-binding-protein
MSRRFLIGAGAAFTLLPAAATPALALTEGRARALIDQVVADINRVIGSGKSTSAMIRDFERIFARYADVNIIARSTLGADSRRASSGQMRAFTAAFQGYIARKYGKRFREFVGGQVSVTGVRQVKSWHEVRANVKLRGKSPFTVLFLVSDRSGRDLFFDMVIEGVSLRLTERTEIGAMLDRNGGNIDALIADVQRAG
>NZ_CP045410.1|WP_152496713.1|1935864_1936623_+|VacJ-family-lipoprotein
MAGLLLAVGLAVSGCTPTPAGHPPGEVFDPYEGENRRTHTFNRALDRKLLRPAGKGASGFIPDDVENMIGRFAFHLSIPGAVVNNILQGNMKGATEDTYRFVVNTTIGLGGLFDTATELNMPQATDADFGQTLHVWGVREGAYLELPLLGPSTERAAAGKVVDLFTNPLSYVLDEPANYAIPAASAASGLSDRGRYADTIDSILYESADSYAQARSLYSQNRRFKLGGGSGGALEDPYDAQLGALPEDPYDE
>NZ_CP045410.1|WP_152496712.1|1933921_1935658_-|type-I-secretion-system-permease/ATPase
MQLSKARLDAGREELRAARRESRALYWFVGVLSFFVNLLMLTGPLYMLQVYDRVLGSRSVETLIALSVLVVFLYGMMGLLDYARGRIMGRVAARFQARLDRRVFDAVIRKAALAPDEHTQTGLRDLEAVQRLMASPVLMAIFDMPWTPVFLAGIWLFHPWLGALALIGGGIIILVTLVNQMVTRQPAMKSARATGAAEALSSQIRNESEMVQAMGMRDQAFSRWQKARDESLKSQIASSDLVGTFTTTTRTFRLFLQSAMLGLGAYLVLQNALTPGAMIAGSILMGRALAPIELAVGQWALVQRAMQGWDSLARLLALVPPEQPRTPLPKPKALLEVRQVTVVPPGDQQAALKTIGFTVEPGQAVGVIGPSGAGKSTLARALTGVWRPAGGKIRLDGASLDQFEPRVLGEHIGYLPQRVQLFEGTIAENISRLAEEPDPAKIVAAARKADAHDMILKLPDGYDTRINAGGGRLSGGQMQRIGLARAMYGDPVLVVLDEPNSNLDNEGSEAVNHAIRQFKAEGKSVLIMAHRPAAIRECDLLLMLDGGVVRSFGPKDEVLKDVVKNAEEIGHARIGGVQ
>NZ_CP045410.1|WP_152496720.1|1946053_1946920_-|SDR-family-NAD(P)-dependent-oxidoreductase
MGKVLLSFGHGFSARALARRLVPQGWRVIGTTRSAEKAEALRDEGVEGVVWPGSDLSEVLGAATHLLTSVSPGEDGDPVLNALGDDIAAIAGRLEWAGYLSTTGVYGDHEGDWVDEDSPLEPSTERGQKRVVAEAAWAAIPGLPLHIFRLAGIYGPGRGPFEKVRRGTARRIIKQGQVFSRTHVEDIAQVLEASINRPNPGAAYNVCDDDPAPPQDVIGYAAELLGLPLPPAVDFEEAEMSPMARSFYAESKRVENSRIKDELGVQLIYPDYKAGLEALLAEENAREG
>NZ_CP045410.1|WP_152496721.1|1946929_1947373_-|VOC-family-protein
MDFETVKPEVFGASLRGMGLNLLVRDVAREVAFLEAVFGMRGHRVSGDFAIMVYGDQLMQLHVDATYGSHPALGLLPESGPRGAGAQIHLFDSDPDEAANKAEAAGGHVLQPPTDKPHGLRETTILCENGYAWVASRPLQDISGGEP
>NZ_CP045410.1|WP_152496722.1|1947467_1948952_+|AMP-nucleosidase
MAQTADDGRYHSPEAPAPQNFTEAAAAVDHLVALYDDAVSFLCEAFQAAMLNGQPSRPVRAFYPEIRISTSSYAKIDSRLSFGHLAEPGTYATTVTRPRMFRNYLEQQIGLLLHNHDVPVTIGVSDTPMPVHFAVANDASITVPQQGAADFTLRDYFDVPDLSTTNDDIVNGTYTVMQQSPAPLAPFTAQRVDYSLARLAHYTATAPEHFQNHVLFTNYQFYVAEFEAYARKVLANPDSGYDSFVGPGDATITGPDDVLRPTTKLPQMPTYHLKRKGSSGITLVNIGVGPSNAKTATDHIAVLRPHAWIMVGHCAGLRNSQSLGDFVLAHAYLREDAVLDADLPAWVPIPALAEVQIALEKAVAAETELEGYALKSVMRTGTVASFDNRNWELRDQSGPVQRLSQSRAIALDMESATIAANGFRFRVPYGTLLCVSDKPLHGELKLPGMASDFYKTQVSRHLMIGIHAMEHIRDMPLERIHSRKLRSFDETAFL
>NZ_CP045410.1|WP_152490964.1|1949157_1949592_+|universal-stress-protein
MSKKLVLGFDDSESAKAALDFATTLAKAQGAEVIVAHVLEWSPYSFLTKEELEERHMRRKEELARAEDALLKPVLKRLSDAGITATTVLRYGHIADTLVDIIKENNAEMIVIGRTGHSALSSRLFGSVAGSLAQAAPVPVTIVP
>NZ_CP045410.1|WP_152490963.1|1949633_1951178_+|amino-acid-carrier-protein
MKHAFKTPLAALFALLALSAPALAQSIDETVNEIFANSTGWFVSLIFSDFPGTSFPWIVGWLVIAATVFTVYFGVVQLRWVGHSIALVKGDYSDPNDAGEVSHFQALATALSGTVGLGNIAGVAVAVGIGGPGATFWMILAGLLGMASKFTECTLGVKYRNEYPDGKVSGGPMYYLSKGFKERGIFGGGILAVLFSIFCILGALGGGNMFQANQAHAQLSNVLGDYPGWITGLVMAAVVFAVIVGGLKSIAKVTEKVVPFMGILYVGTALIIIAMNYDQIGTAFGRIFEGAFTGLGVAGGMVGALIQGFRRAAFSNEAGVGSAAIAHSAVRTKEPITEGFVSLLEPFIDTVVVCTMTALVIIITDQLITDPETGLFVLNEAGNAVQTVDGNTGVALTSAAFSSSIDGFKYVLALAVILFAFSTMLSWSYYGLKAWTFLFGEGQTKELIFKLIFCLFVVIGAASSLGPVIDFSDAAIFAMAVVNVLGLYFLMPIVKRELHSYAARLRSGEIKKYK
>NZ_CP045410.1|WP_152496723.1|1951544_1952234_+|ZinT/AdcA-family-metal-binding-protein
MQQTFARCVAAVATGALLVLSAPAFAQSDSTHDHDHDHSEEHDHSEKHDHGDDKVYNGYFEDDQIEDRTLSDWEGDWQSVYPLLQDGTLDPVMAHKAEHGDKTAAEYTDYYETGYATDVDRILIEGDSVTFFEDGTPLQGRYANDGYEVLTYKAGNRGVRYIFEKSGGDAGAPAFIQFSDHAIAPQDAGHFHLYWGDDRAKLLEEVTNWPTYYPAELSGEDVAEEMMAH
>NZ_CP045410.1|WP_152490961.1|1952534_1953605_-|PAS-domain-containing-protein
MKPEDMEMGENEVEQAIRLSPLSMVLTDPRLDDNPITYVNSAFESLTLYSRRYAIGRNCRFLQGEETDAADVQKLRSGLDSAEEFEVVITNHRADGTAFRNQLLVAPIHGSDGALTGFFGLQREIPQTVTMPEQDDATLGLLRELQHRVKNHLAMIVSMIRIQARQDVTEESLKAIGRRIEALSVLYDELLSGGNSEKIETGAYLSRIASVVSSLEPRGAIRVNVECDEVSLPVDQAARLGLLLSEFLTNAFEHAFAGRSTGTVEVRFQRTGAQGLRLSVEDDGIGLPEDSNWPFGAASIETQRERAEDHDGALDTTGDSGKPGVGGSIVVALTQSLEADLSVETLEQGTRVTVEV
>NZ_CP045410.1|WP_172978852.1|1953716_1954394_-|Crp/Fnr-family-transcriptional-regulator
MSASTREAVGARCEPVALKAGDVLHRMGDTTSAVYFPETAVISTLASYSDGSGVEMANVGREACSALNLILRHPRQLAADEVQIAGRALRLPAERFRELKSEYRDFENALFSVVQSVLYQAMVSGACNAAHEAKPRLARWLLTMGDRTDGNEMRLTHDFLAQMLGVRRATVTNAALDLQSQGLIKYARGRLEITDIKGLRGASCECYDLVRSANAELLPDKRSGD
>NZ_CP045410.1|WP_152496725.1|1954540_1955386_+|helix-turn-helix-domain-containing-protein
MEILIPHRLATLGHPQRMAVFRLLMRRYPDAVPATELAHALDLKPNTLSTYVNALAQAGLITRTRQGTSLRYSVDMTAIRQTLDYLIGDCCRGRPDACSTTSLHTLLGVPQMTDRKYNVLFICTGNSARSIFAESLLRAEAGDRFNAYSAGTKPRSELNPFALDVLEQKGHDTSVLEAKNVSVFQGPDAPQFDFVFTVCNQAANEECPAWTGQPVSAHWGMPDPVKAEGTDAQKALAFQQAYGALQNRIKAFTSLSLDSLDRISLQKAVDDIANINSGASA
>NZ_CP045410.1|WP_152496726.1|1955382_1956381_+|ArsJ-associated-glyceraldehyde-3-phosphate-dehydrogenase
MTTYAVNGLGRIGKLILKPLLERGAKIAWINDAVGDAEMHAHLLEFDTVHGRWDAEFAHDSDSVTIDGTRLSFIGTKDLSALPLDGVDVVIDCTGVYKTEAKLAPYFEAGVKKVVVSAPVKDGDAANIVMGVNHDIYDAARHRIVTAASCTTNCLAPVVKVIHENLRIKHGSMTTIHDVTNTQTIVDRPAKDLRRARSALNSMIPTTTGSATAITLIYPELKGRLNGHAVRVPLLNASITDCVFEVERETTAEEVNSLFKAASEGSLKNILGYEERPLVSADYTNDTRSGIVDAPSTMVVNGTHVKIYAWYDNEMGYAYRLVDVALMVGASL

Crispr_ID: NZ_CP045410_5

• CRISPR_ID: NZ_CP045410_5
• CRISPR_location: 3303628-3303790
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP045410_5

Consensus_repeat	Method
CTCGCCTTCGTAGACATCGCCGTTG	CRISPRCasFinder

spacers of NZ_CP045410_5

>5.1|3303653|44|NZ_CP045410|CRISPRCasFinder
GGATAGGTGATCGTCGCCGTGCCTTCCTTGACGCCGTTCACCCA
>5.2|3303722|44|NZ_CP045410|CRISPRCasFinder
GGGCTTTCCATTTTGCCGCGGCCGTGGTGCTGGGCGTTGCGGAA

CRISPR arrays and Neighbor proteins around NZ_CP045410_5

CRISPR arrays

The CRISPR arrays of NZ_CP045410_5

>merge|NZ_CP045410|5|3303628-3303790|CRISPRCasFinder
CTGGCCTTCATAGACCGCACCATCGGGATAGGTGATCGTCGCCGTGCCTTCCTTGACGCCGTTCACCCAGTCGCCGTCGTAGACATAGCCGCCGGGGCTTTCCATTTTGCCGCGGCCGTGGTGCTGGGCGTTGCGGAAGCCGCCCTCGTAGCGGACGCCGTTG

>NZ_CP045410|5|5|3303628-3303790|CRISPRCasFinder
CTGGCCTTCATAGACCGCACCATCG	GGATAGGTGATCGTCGCCGTGCCTTCCTTGACGCCGTTCACCCA
GTCGCCGTCGTAGACATAGCCGCCG	GGGCTTTCCATTTTGCCGCGGCCGTGGTGCTGGGCGTTGCGGAA
GCCGCCCTCGTAGCGGACGCCGTTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045410.1|WP_152497614.1|3300789_3302319_+|cryptochrome/photolyase-family-protein	unknown	unknown	gnl|CDD|225588
NZ_CP045410.1|WP_152497621.1|3314436_3315348_-|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293806
NZ_CP045410.1|WP_152493450.1|3311138_3312200_-|polyamine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|226361
NZ_CP045410.1|WP_152493459.1|3298301_3299867_-|2-isopropylmalate-synthase	unknown	unknown	gnl|CDD|234864
NZ_CP045410.1|WP_152497617.1|3308383_3309415_-|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|270382
NZ_CP045410.1|WP_152497612.1|3296274_3297297_+|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|270260
NZ_CP045410.1|WP_152497610.1|3293501_3294176_+|nitroreductase-family-protein	unknown	unknown	gnl|CDD|380313
NZ_CP045410.1|WP_152493452.1|3309441_3310248_-|ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|224098
NZ_CP045410.1|WP_152498286.1|3300130_3300796_+|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|181609
NZ_CP045410.1|WP_152497607.1|3290826_3291957_+|SPFH-domain-containing-protein	unknown	unknown	gnl|CDD|372597
NZ_CP045410.1|WP_152497618.1|3310240_3311137_-|ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|224097
NZ_CP045410.1|WP_152497620.1|3314001_3314397_-|metallopeptidase-family-protein	unknown	unknown	gnl|CDD|240572
NZ_CP045410.1|WP_172978902.1|3316934_3319040_-|nitrate--and-nitrite-sensing-domain-containing-protein	unknown	unknown	gnl|CDD|214599
NZ_CP045410.1|WP_152497611.1|3294186_3296079_-|acyl-CoA-synthetase	unknown	unknown	gnl|CDD|236043
NZ_CP045410.1|WP_152497616.1|3304330_3305989_+|NAD+-synthase	unknown	unknown	gnl|CDD|237577
NZ_CP045410.1|WP_152497622.1|3315527_3316853_+|glutamate--tRNA-ligase	unknown	unknown	gnl|CDD|183594
NZ_CP045410.1|WP_152497619.1|3312262_3313708_-|amidase	unknown	unknown	gnl|CDD|223232
NZ_CP045410.1|WP_152497613.1|3297473_3298235_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|180993
NZ_CP045410.1|WP_152497609.1|3292401_3293505_+|primosomal-protein-N'-(replication-factor-Y)---superfamily-II-helicase	unknown	unknown	gnl|CDD|371721
NZ_CP045410.1|WP_172978901.1|3291953_3292397_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP045410.1|WP_152497614.1|3300789_3302319_+|cryptochrome/photolyase-family-protein	gnl|CDD|225588	COG3046, COG3046, Uncharacterized protein related to deoxyribodipyrimidine photolyase [General function prediction only].	0
NZ_CP045410.1|WP_152493450.1|3311138_3312200_-|polyamine-ABC-transporter-ATP-binding-protein	gnl|CDD|226361	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism].	9.86412e-163
NZ_CP045410.1|WP_152493459.1|3298301_3299867_-|2-isopropylmalate-synthase	gnl|CDD|234864	PRK00915, PRK00915, 2-isopropylmalate synthase; Validated.	0
NZ_CP045410.1|WP_152497617.1|3308383_3309415_-|extracellular-solute-binding-protein	gnl|CDD|270382	cd13664, PBP2_PotD_PotF_like_3, TThe periplasmic substrate-binding component of an uncharacterized active transport system closely related to spermidine and putrescine transporters; contains the type 2 periplasmic binding fold. This family represents the periplasmic substrate-binding domain that functions as the primary high-affinity receptors of ABC-type polyamine transport systems. Polyamine transport plays an essential role in the regulation of intracellular polyamine levels which are known to be elevated in rapidly proliferating cells and tumors. Natural polyamines are putrescine, spermindine, and spermine. They are polycations that play multiple roles in cell growth, survival and proliferation, and plant stress and disease resistance. They can interact with negatively charged molecules, such as nucleic acids, to modulate their functions. Members of this family belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	6.86572e-143
NZ_CP045410.1|WP_152497612.1|3296274_3297297_+|extracellular-solute-binding-protein	gnl|CDD|270260	cd13542, PBP2_FutA1_ilke, Substrate binding domain of ferric iron-binding protein, a member of the type 2 periplasmic binding fold superfamily. FutA1 is the periplasmic component of an ABC-type iron transporter and serves as the primary receptor in Synerchosystis species. The periplasmic iron binding protein plays an essential role in the iron uptake pathway of Gram-negative pathogenic bacteria and is critical for survival of these pathogens within the host. After binding iron with high affinity, FutA1 interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The iron- and thiamine-binding proteins belong to the PBPI2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.64289e-146
NZ_CP045410.1|WP_152497610.1|3293501_3294176_+|nitroreductase-family-protein	gnl|CDD|380313	cd02136, PnbA_NfnB-like, nitroreductase similar to Mycobacterium smegmatis NfnB. Members of this family utilize FMN as a cofactor and catalyze reduction of a variety of nitroaromatic compounds, including nitrofurans, nitrobenzens, nitrophenol, nitrobenzoate and quinones by using either NADH or NADPH as a source of reducing equivalents in an obligatory two-election transfer mechanism. The enzyme is typically a homodimer. Mycobacterium smegmatis nitroreductase NfnB plays a role in resistance to benzothiazinone.	3.6645e-30
NZ_CP045410.1|WP_152493452.1|3309441_3310248_-|ABC-transporter-permease-subunit	gnl|CDD|224098	COG1177, PotC, ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism].	1.50293e-80
NZ_CP045410.1|WP_152498286.1|3300130_3300796_+|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|181609	PRK09009, PRK09009, SDR family oxidoreductase.	3.76311e-56
NZ_CP045410.1|WP_152497607.1|3290826_3291957_+|SPFH-domain-containing-protein	gnl|CDD|372597	pfam13421, Band_7_1, SPFH domain-Band 7 family.	3.16947e-131
NZ_CP045410.1|WP_152497618.1|3310240_3311137_-|ABC-transporter-permease-subunit	gnl|CDD|224097	COG1176, PotB, ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism].	3.3366e-91
NZ_CP045410.1|WP_152497620.1|3314001_3314397_-|metallopeptidase-family-protein	gnl|CDD|240572	cd12952, MMP_ACEL2062, Minimal MMP-like domain found in Acidothermus cellulolyticus hypothetical protein ACEL2062 and similar protein. The subfamily includes an uncharacterized protein from Acidothermus cellulolyticus (ACEL2062) and its homologs from bacteria. Although its biological role remains unclear, ACEL2062 contains a minimal metalloprotease (MMP)-like domain consisting of 3-stranded mixed 2-beta sheets and a HExxHxxGxxD/S (x could be any amino acid) motif. It may belong to a superfamily of bacterial zinc metallo-peptidases, which is characterized by a conserved HExxHxxGxxD motif.	5.50713e-43
NZ_CP045410.1|WP_172978902.1|3316934_3319040_-|nitrate--and-nitrite-sensing-domain-containing-protein	gnl|CDD|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	4.08977e-56
NZ_CP045410.1|WP_152497611.1|3294186_3296079_-|acyl-CoA-synthetase	gnl|CDD|236043	PRK07529, PRK07529, AMP-binding domain protein; Validated.	0
NZ_CP045410.1|WP_152497616.1|3304330_3305989_+|NAD+-synthase	gnl|CDD|237577	PRK13981, PRK13981, NAD synthetase; Provisional.	0
NZ_CP045410.1|WP_152497622.1|3315527_3316853_+|glutamate--tRNA-ligase	gnl|CDD|183594	PRK12558, PRK12558, glutamyl-tRNA synthetase; Provisional.	0
NZ_CP045410.1|WP_152497621.1|3314436_3315348_-|MBL-fold-metallo-hydrolase	gnl|CDD|293806	cd07720, OPHC2-like_MBL-fold, Pseudomonas pseudoalcaligenes organophosphorus hydrolase C2, and related proteins; MBL-fold metallo hydrolase domain. Pseudomonas pseudoalcaligenes OPHC2 is a thermostable organophosphorus hydrolase which a broad substrate activity spectrum: it hydrolyzes various phosphotriesters, esters, and a lactone. This subgroup also includes Pseudomonas oleovorans PoOPH which exhibits high lactonase and esterase activities, and latent PTE activity. However, double mutations His250Ile/Ile263Trp switch PoOPH into an efficient and thermostable PTE. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	4.80076e-79
NZ_CP045410.1|WP_152497613.1|3297473_3298235_+|SDR-family-oxidoreductase	gnl|CDD|180993	PRK07478, PRK07478, short chain dehydrogenase; Provisional.	5.74849e-119
NZ_CP045410.1|WP_152497609.1|3292401_3293505_+|primosomal-protein-N'-(replication-factor-Y)---superfamily-II-helicase	gnl|CDD|371721	pfam11781, zf-RRN7, Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7. This is the zinc-finger at the start of transcription-binding factor that associates strongly with both Rrn6 and Rrn7 to form a complex which itself binds the TATA-binding protein and is required for transcription by the core domain of the RNA PolI promoter.	4.21963e-06
NZ_CP045410.1|WP_152497619.1|3312262_3313708_-|amidase	gnl|CDD|223232	COG0154, GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis].	2.15848e-102

Protein sequences

>NZ_CP045410.1|WP_152497614.1|3300789_3302319_+|cryptochrome/photolyase-family-protein
MVKRLILVLGDQLSNNLSALRDADKERDIVVMAEVADEASYVGHHPKKIALIFAAMRHFAEELQDDGWQVAYSRLDDDDTSKSIVGELMRRGQEHDTTEVVATRPGEWRLVEALDNAPLTVTMLPDDRFVASLDEFNTWAEGRKSLRMEYFYRDMRRKTGLMMEGDEPAGKKWNYDHENRKPASGDMLRSKPMEFTPDKITEEVLDLVEEKFGNNFGALRPFTYAVSRGQALRALDHFAKNLLDCFGDYQDAMLQDDRFLHHSLLSQYLNIGLLDPVEICTRVEEEWKAGNVPINAAEGFIRQIIGWREYVRGIYFREGPDYVTRNALGHERDLPWMYWGGETQMNCVAHAVDQTRELAYAHHIQRLMVTGNFALLAGVDPHQVHEWYLAVYHDAFEWVEAPNVIGMSQFADDGIIASKPYVSSGNYIDKMSDYCGSCAYSVKDKTGEKACPFNLLYWDFLVRHREKFSNNPRMGQMYATWDRMKDDRKDAVLKGAKRILDRLDACEIV
>NZ_CP045410.1|WP_152498286.1|3300130_3300796_+|SDR-family-NAD(P)-dependent-oxidoreductase
MKDALVIGASGGIGSALVSALEKRDVRVTGLSRSGDGLDVTDEASVEAHLGALEGEYDLVFVATGALELEGSGPEKSLKELRSEAMEAQFRVNCIGPSLVLKHSVRLLPRDRECRFAALSARVGSIGDNGLGGWYSYRTAKAAVNQMIHGGAIELARTHGQSICVALHPGTVETPLTKKFAGGHTTVTPEEAAQNLLDVLAGLTPENTGQFFDWAGEPVPW
>NZ_CP045410.1|WP_152493459.1|3298301_3299867_-|2-isopropylmalate-synthase
MTNSEQNRVVIFDTTLRDGEQSPGATMTHAEKLEIAGLLDEMGVDIIEAGFPIASEGDFRAVSEIAKNAKNSVICGLARANLKDIDRCWDAVKHASQPRIHTFIGTSPLHRAIPNLNKDEMAERIHETVTHARNLCDNVQWSPMDATRTEWDYLARVVEIAIKAGATTINIPDTVGYTAPVESADLIRRLIAEVPGADEVVFATHCHNDLGMATANSLAAVEGGARQIECTINGLGERAGNTALEEVVMAMKVRNDIIPYHTRIDSTKIMHLSRRVATVSGFQVQPNKAIVGKNAFAHESGIHQDGMLKNAETFEIMRPEDVGLTETNIVMGKHSGRAALRSKLKNLGIDLAENQLSDVFVRFKELADRKKEVFDEDLIALVTAGEDAENDRLVLKSLRVVCGTGGQAEAEMVMSIDGVETSATEQGDGPVDATFKAVRQLHPNDAHLSLYQVHAVTEGTDAQATVSVRLEEGGNIATGQSADTDTVVASAKAYINALNRLLTRRAKLGENEKEVSYKDVS
>NZ_CP045410.1|WP_152497613.1|3297473_3298235_+|SDR-family-oxidoreductase
MLLQDRSIIITGASSGIGAAAALIFAAQGARLVLGARRADMLSRIAGQINQSNGHAVAVAGDVCDPGYAQRLVDAARDAYGGLDGALNNAGTVGSGAMLADTQDAEWAEVLATNLTAGFHAARAQIPALRERGGGSLVFTGTFVGHTATLPGMGAYAASKAGLVGLVQAIAVETGGEGIRANVLMPGGTMTEMAKDAATNPETADFIAGLHALKRMAQPQEIANAALFLLSDLSSFVTGAAMLADGGNSIAKV
>NZ_CP045410.1|WP_152497612.1|3296274_3297297_+|extracellular-solute-binding-protein
MAHLTSRSLVAALALSGVAMPAVAQEVNVYSSRHYDTDDSLYEAFTEETGITVNRIEADADELIARLEAEGENSPADVLITVDAGRMARAEELDLLAAYDSQTIEDRIPDHLEHPENLWYGIAQRARIIYYDKEKVENPPQTYEELADPAWEGKICIRSSSNIYNQSLMASIIETHGEEAAKEWAQGIVNNMARDPQGGDTDQLRGIVSGECEVAVGNHYYFVRGFESDVEGLSDGIEKIGWVWPNQDDRGTHVNLSTAAMLKTAPNPENAMKLMEFFTSDTAQTNLATGNHEYPAVEDAPGTATTERLGEFKPDETTPTAAFSRNAAKAQELFNAVGWD
>NZ_CP045410.1|WP_152497611.1|3294186_3296079_-|acyl-CoA-synthetase
MTFSTRQDVIAIQQEMPWEARDVPKTVYQMLADTATAFPDRPAVSYQLLSGPMDKSQTLTWSEFHGRVCQAANLFRSLKISETDVIALVMPNCLETAIATIGAMVAGIANPINPLLEPEQIGAILRETDARVVVTLRSFPKTDVAQKMAEAVRNAPRVHTVLEVDLVRYLTPPKSWIVPLIRPKNPDNHHADVKNFNAEARKHPNTLVFKDSATDRVAAYFHTGGTTGMPKVAQHKYSGMVYNGWLGHRLLFDEHDSIMCPLPLFHVFACHVILMAMIKSGAHVVFPTPAGYRGDGVFDNFWKLLERWGTTFVITVPTATAALMQRKVNADISKVKNAFSGSAPMPLELFKRFESATGMTVIEGYGLTEATCLVSCNPPTGEKKVGSVGVPLPYTDVKIYKTDGTECGPDEVGEIGIANPGVFAGNTYTEVAKNKDLYHHEVYLRTGDLGRIDDDGYLWITGRAKDLIIRGGHNIDPADIEEALMAHAEVAGAGAIGQPDAHSGELPCAYVELVSGGSVDSAALLEHCKVHVHERAAIPKYIEVLDELPKTAVGKVFKPDLRKRAITRVYNAALADAGINAEVTEVIDDKKRGLVACLSKTGDADEAAISQCLGEFTRPWIWADAKPKAD
>NZ_CP045410.1|WP_152497610.1|3293501_3294176_+|nitroreductase-family-protein
MSGDGDALKRLMQARYSCRAFRPDPVADAVIERIVDTARHTASWNNTQPWELLVTRGTETEAFRQALLSEVRTGKPGPDMDWPESYPGELGERRRTCGYALYNAVGIAREDREARARQSMRNFELFDAPHVAILHIPQVLGPYGALDAGGFLTAFMLAATAEGLGTIAQAAVAAYPHVIRRQFGLPEHHAILCAISFGYADETHPVNQYRTEREDVGAILSFKG
>NZ_CP045410.1|WP_152497609.1|3292401_3293505_+|primosomal-protein-N'-(replication-factor-Y)---superfamily-II-helicase
MLDSPTVDQEHRFPCDQCGADFRFDPQAGKLICDHCGNEAEMEQAGPWAAPLKELDFGAAVKGTLDASEIEETRVATCPNCAAQVEFDATVHARECPFCATPVVTDTGTHRHIKPRGVLPFKVDEPAARGAMTDWLGRLWFAPNGLQEYARKGRKMQGIYVPYWTYDADTRSSYTGERGTVYYETKTVMRDGKRQQVQVAKVRWTPVRGRVARFFDDVLVLASKTLPKRYTDALEPWELGELQPYSPEFLAGFRAEGYQVTLEDGFVQARQIMDARIARDVRFDIGGDRQRIHSIDTAVSDVTFKHILLPVWLAAYKYRGETYRFVVNGRTGKVQGERPYSAIKIAIAVVIGIIVAAAVGYGVAISQ
>NZ_CP045410.1|WP_172978901.1|3291953_3292397_+|hypothetical-protein
MRAFKARRLATQVLHWTTGVLLYLLLSVDDRIFGLLGWAFVVSGGALCVLWLCFGLLNKGPGPALEGVLRTAHPWLSRGMYVLLGWAVVALAAGALERPLPGPEARTALLVLGAAALFHAIFHLWRHTALRDGALRRIIPVKLHKYL
>NZ_CP045410.1|WP_152497607.1|3290826_3291957_+|SPFH-domain-containing-protein
MGIFDFLSGEFIDVIHWVDDTRDTMVWRFERHGHEIKYGAKLTVREGQAAVFVHEGQLADVFTPGLYMLETNNMPIMTTLQHWDHGFQSPFKSEIYFVNTTRFTDLKWGTKNPIMLRDPEFGPTRIRAFGTYSTRVTDPAKFLTEIVGTDGEFTMDEISYQVRNIIVQSFSRIIAGSGIPVLDMAANTADLGKLVAAEISAVVADYGLTIPEFYIENISLPPAVEEALDKRTSMGLAGDLGKFTQYSAAEAMTAAAKNPGGAGGGMGAGIGAGLGMAMAGQMAGQGGPWGQAAHQPSSAAAPAPPPPPVEHVWHIAENGQTHGPYSKAALGRMASDGKLTRDSHVWTAGQDGWLKAGDVQELAQLFTILPPPPPGA
>NZ_CP045410.1|WP_152497616.1|3304330_3305989_+|NAD+-synthase
MADRFRVTLAQLNATVGDLGGNAALARKAWEAGREAGADLVALPEMFITGYNTQDLIRKPVFHQAAIAKIEDLAKECAVGPALAIGGPALEGAELYNAYYILKGGSITACVLKHHLPNETVFDEVRLYASGDVMGPYAVDGVRIGSPICEDSWHDDVPETLAETGAEFLLVPNGSPYYRGKLAHRHQLMVNRVVETGLPLIYLNLVGAQDDQVFDGGTFALNPGGGLAVQMPLFEEDIAHVDLVRGDDGWRIETKALAHIPDTLESDYHAMVLALRDYMRKTGFGKVLLGLSGGVDSAIVATIAVDALGAENVRCVMLPSEYTSQGSLDDAKACAKALGARYDFVPIAEGRAAITNTLAPLFEGTEPGITEENIQSRLRGLLLMALSNKFGEMLLTTGNKSEVAVGYATIYGDMAGGYNPIKDLYKTRVFDVCRWRNANHRDWMMGPGGEVIPETIIEKPPSAELRADQKDSDSLPDYPVLDGILQILVDEDGSIEDCVKAGYSRADAARVEHLIYISEYKRFQSAPGTRLSKRAFWLDRRYPIVNRWRDGG
>NZ_CP045410.1|WP_152497617.1|3308383_3309415_-|extracellular-solute-binding-protein
MTMKTYLTTTVATIALAGAAHAEGSLNIYNWGNYTSPEMIEKFEQEFDVDVTITDYDSNTTALAKIEAGGHGFDIVVPTHSYMGVYIDKGLLMKPGIPEMENYGNISEQWKNVEWDPNREYSVPWQWGTTGIAVNKSAYDGDINTSSIFLDPPEELVGKVNVVPEMQDVMNLTLFYVGGEPCTTDKEMLKKARDVLIEAKPKWMSMDYGMTEKLSNGDVMASVNWNGSTFRARNNNEDVSYGYPKEGYPVWMDSAAILADAQNVENAKLFLNFIMDPENAAMLSDFARYANGIDGSEEFMPEDMRSAPEIVVPEDLKAAGQFTTACPAEAQEFYTAIWTELQK
>NZ_CP045410.1|WP_152493452.1|3309441_3310248_-|ABC-transporter-permease-subunit
MAKGKSFSVTTLPGFTAIALTTFVLLYAPIVTMVIYSFNDSQSVALWGGFSTRWYVEAWDNTQVQEATVRSLVIAVSAAFISTTVATMAALGTTRRGRFKGQTLIYVMINQPLMVPEIVTAVALLIFFASIKVATGYTGLAYLILAHSAFCVPFAYLPIRARLEGMDLALETAASDLYARPWQTFRHVTLPLMMPGIAAGAMLAFVISLDDVIITEFVKSAGQDTLPTYMLGQLRRVVTPEVNAISTALLALTVLLLTAFFILNRKRD
>NZ_CP045410.1|WP_152497618.1|3310240_3311137_-|ABC-transporter-permease-subunit
MAGTTHGSGRTGWILSIPALILLALGAAGPLLIVVVYAFLEPGEYSGVVWDFTTEAWFRVFFERDIFDDTVTFADAHLTIFWRSVKLSVLTTLIAFAIGFPTAWFIATRPPNKRGFWLFLITIPFWTNLLIRTFAIMEVVRNQGLLNSFLMNLGIIDQPLQILYTDTAVLIGMAYVYLPLMVLPLFAAIDRFDFRLVEAGYDLYATRMKVLRRVILPIVKPGIVAGSILVFVPSLGAYVTPRILSGGKNMMIGNFIELQFGQGRNWPLGAALSLLLLMIVLVALLAYVRVTSRDETNG
>NZ_CP045410.1|WP_152493450.1|3311138_3312200_-|polyamine-ABC-transporter-ATP-binding-protein
MTEAAVEARSARKEYGAGEKKVRALNDVSVVINKGEFFTLLGPSGCGKTTLLRLIAGFESPTAGMILLGARDISTMAPYDRPVNTVFQSYALFPHLSVADNIGFGLTMQGTPKAQVQARVAEMLALVKLEAFAARKPQQLSGGQQQRVALARALAPAPEVLLLDEPLSALDLKLRKEMQLELKRLQTETGITFVFVTHDQEEALTMSDRIGVMRDGSILQIGGPREIYNKPVNRFVADFIGETNVLIGTVEQGGVRLPTGDVIAVDNLDAATQGTKVSLAVRPEQVRIGDGALQGRVAETVYFGTDTHCHLRMSDDTEVVARMQSPPSGDTGLQEGQTVAFDFVPGAVRVLED
>NZ_CP045410.1|WP_152497619.1|3312262_3313708_-|amidase
MDDYRAHDMTSLAGLVAKGEVTPDDLLDTALARMHAVNPALNAVVHDYSDTARRMIADGLPKGPLTGVPFLLKDMGAESTRHPASLGSRLLANTSYRMNSTIYDRLEASGLVTFGRTAAPEGGVGAATEAAVYGGPTRNPWDTSRTPGGSSGGSGAAVAAGIVPGAHGSDGGGSIRIPASNCGLVGFKPTRAMVPDGPYAGEGWAGMAIEGFLTRSVRDTALLLDIVCGPDLGAPYVAPPMPCTFMESLDRPNGPLRIALCDTTLTGEAIHPECQVAVQDAAALLHDMGHHVTQARPAADTTGMMHAWTKIVACGTASWVRAALAKQGRELRQGDIEGVARGAVEYAKTISGADYLDAVETVHAYGRQMAAFFVDHDILLTPTMAEPPAAIGRFAHDTEDYVAYRVGEGGIFAYSPYTAAFNATGQPAVSLPLCRGADGLPIGIHLAARFGADTALMSLCADIERARPWFDQIPALPGIDT
>NZ_CP045410.1|WP_152497620.1|3314001_3314397_-|metallopeptidase-family-protein
MPAPDTSLDWMEDVARRTVAGFPQAFAEAARAVAIHVADWPDREMLDSLDMTDPVELTGLYDGIPMTEKSVFDQPTGPDIVWLFRQPILAEWRDRGDVDLADLVAHVTVHEFAHHFGWSDDDIASIDRWWE
>NZ_CP045410.1|WP_152497621.1|3314436_3315348_-|MBL-fold-metallo-hydrolase
MSTLSRRTFLASATALSAAPALPAWATAPMLGAATPPFRRFKLGAFEVTTLLAGEATRPDPHTIFGLNVDEAEFTAVSEAAMIPTDQAQFFFTPTVVNTGSELVLFDTGLNAEGTTAALDAAGYSADMIDTVVITHMHGDHIGGLMEGDAPTFANADYVTGSAEFDHWSAAGDDNFEAKVRPLAEQFTMIGDGDAGFSGHTAMAAFGHTPGHMVHLIESEGESLMIAADFANHYVWSLAHPDWEVKFDMDKAAAAQTRKTILDMLAAEKMPFIGYHMPWPATGFVEKTDSGYAYVPSSYQLRL
>NZ_CP045410.1|WP_152497622.1|3315527_3316853_+|glutamate--tRNA-ligase
MTTTRFAPSPTGYIHIGNLRTALMNFLIARKNGGTFILRIDDTDPERSKQEYVDAIKQDLEWLGLTWDRVERQSERLDRYAQAAETLRGMGRFYEAFETPTELDLKRKKQLNMGKPPVYDRAALGLSDEQKDALRAERGDGVWRFKLDHERIEWDDGILGDISIDAASVSDPVLIRGDGQVLYTLASVVDDTEMGVTHVVRGSDHVTNTATQIQIIEALGGTVPSFAHHSLLTGPQGESLSKRLGTLSLRDLRAQGVEPMALLSLMARLGSADPVELRSEMAELIEGFDISRFGSAPTKFDANDLFPLTARVLQGRDFADVKAHILGLGVPEDQAERFWSVTRENITTLHDLEPWWVMFRDGAEPVIDDEDREFVAQALALLPEGPHDGDTWGQWTNAVKEETGRKGKGLFMPLRKALTGQNHGPDMSQVLPLLQVIRAKG
>NZ_CP045410.1|WP_172978902.1|3316934_3319040_-|nitrate--and-nitrite-sensing-domain-containing-protein
MRLRVVMFLVIAPLFAAVGYLTSVEVAQKRADAGQAETSRILAHESAIVGALVHELQKERGFSAGLIASRGANFRSDLARQRTDSDAAIAAFAAEVSALRRARPPEIASVNTRLDQLEDMRKQVDAFGLAVPDMAAFYTETITHLLELERPVAARTTRGETNALLEARTLLSAAKEAAGLERAMGATGLGSGFRPAVFNRYLRLNGAQEALLTEAAGTLEDPEWLARIRASDASATIRSARDRILAGTRTRNFDGLTAPEWFAISTAWIDLLRAEELKLFEAVRVKSAEIEATADTTLKRFAIFGSVLAVSVLAFAVFAFERMIARIKYLISVINKFTGGDFSVYIDGIDSKDELGQMASAIFHFKQETIEMRKGAEALKADQERIKAEQDQVVTALRDGLNRLSDGDLAQRFDNPFPQEYESLRHDFNTTVSRLNDALCKVVDATRSIRSGSGALERSSGDLSFKAEEQAQNVRNTADAVKEVTSSVRAASLGAGEVQQTTQAAKNAALESDPVVRQAVDAMEEISGSSEQIAQIIVLIEDIAFQTNLLALNAGVEAARAGDAGRGFAVVASEVRALAQRSTEAAMQIKTLIGNSSLQVKNGVELVNEAGTALKSILERVAQIDKLVADMAKATEEQASELENINTTVTRVDSVTQETATMAAEARTTCEDLNTYAGHLEQLVGQFSLTRPERDGLPSAA

Crispr_ID: NZ_CP045410_4

• CRISPR_ID: NZ_CP045410_4
• CRISPR_location: 3303352-3303515
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP045410_4

Consensus_repeat	Method
CTCGCCTTCGTAGACATCGCCGTTG	CRISPRCasFinder

spacers of NZ_CP045410_4

>4.1|3303377|44|NZ_CP045410|CRISPRCasFinder
GAGCCGGTGAAGGTGCCTTGCCCGTGGCGGCTGTCATCGGCGAA
>4.2|3303446|44|NZ_CP045410|CRISPRCasFinder
TTGTAGACCACGCGGCCCGTGCCCTCGCGCCGGCCCGCCACGAG

CRISPR arrays and Neighbor proteins around NZ_CP045410_4

CRISPR arrays

The CRISPR arrays of NZ_CP045410_4

>merge|NZ_CP045410|4|3303352-3303515|CRISPRCasFinder
GGAGCCTTCGTAGCGGTAGCCGTCGGAGCCGGTGAAGGTGCCTTGCCCGTGGCGGCTGTCATCGGCGAACTCGCCTTCGTAGACATCGCCGTTGTTGTAGACCACGCGGCCCGTGCCCTCGCGCCGGCCCGCCACGAGCTCGCCTTCGTAGACGTCGCCGTTGG

>NZ_CP045410|4|4|3303352-3303515|CRISPRCasFinder
GGAGCCTTCGTAGCGGTAGCCGTCG	GAGCCGGTGAAGGTGCCTTGCCCGTGGCGGCTGTCATCGGCGAA
CTCGCCTTCGTAGACATCGCCGTTG	TTGTAGACCACGCGGCCCGTGCCCTCGCGCCGGCCCGCCACGAG
CTCGCCTTCGTAGACGTCGCCGTTGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045410.1|WP_152497614.1|3300789_3302319_+|cryptochrome/photolyase-family-protein	unknown	unknown	gnl|CDD|225588
NZ_CP045410.1|WP_152497621.1|3314436_3315348_-|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293806
NZ_CP045410.1|WP_152493450.1|3311138_3312200_-|polyamine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|226361
NZ_CP045410.1|WP_152493459.1|3298301_3299867_-|2-isopropylmalate-synthase	unknown	unknown	gnl|CDD|234864
NZ_CP045410.1|WP_152497617.1|3308383_3309415_-|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|270382
NZ_CP045410.1|WP_152497612.1|3296274_3297297_+|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|270260
NZ_CP045410.1|WP_152497610.1|3293501_3294176_+|nitroreductase-family-protein	unknown	unknown	gnl|CDD|380313
NZ_CP045410.1|WP_152493452.1|3309441_3310248_-|ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|224098
NZ_CP045410.1|WP_152498286.1|3300130_3300796_+|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|181609
NZ_CP045410.1|WP_152497607.1|3290826_3291957_+|SPFH-domain-containing-protein	unknown	unknown	gnl|CDD|372597
NZ_CP045410.1|WP_152497618.1|3310240_3311137_-|ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|224097
NZ_CP045410.1|WP_152497620.1|3314001_3314397_-|metallopeptidase-family-protein	unknown	unknown	gnl|CDD|240572
NZ_CP045410.1|WP_172978902.1|3316934_3319040_-|nitrate--and-nitrite-sensing-domain-containing-protein	unknown	unknown	gnl|CDD|214599
NZ_CP045410.1|WP_152497611.1|3294186_3296079_-|acyl-CoA-synthetase	unknown	unknown	gnl|CDD|236043
NZ_CP045410.1|WP_152497616.1|3304330_3305989_+|NAD+-synthase	unknown	unknown	gnl|CDD|237577
NZ_CP045410.1|WP_152497622.1|3315527_3316853_+|glutamate--tRNA-ligase	unknown	unknown	gnl|CDD|183594
NZ_CP045410.1|WP_152497619.1|3312262_3313708_-|amidase	unknown	unknown	gnl|CDD|223232
NZ_CP045410.1|WP_152497613.1|3297473_3298235_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|180993
NZ_CP045410.1|WP_152497609.1|3292401_3293505_+|primosomal-protein-N'-(replication-factor-Y)---superfamily-II-helicase	unknown	unknown	gnl|CDD|371721
NZ_CP045410.1|WP_172978901.1|3291953_3292397_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP045410.1|WP_152497614.1|3300789_3302319_+|cryptochrome/photolyase-family-protein	gnl|CDD|225588	COG3046, COG3046, Uncharacterized protein related to deoxyribodipyrimidine photolyase [General function prediction only].	0
NZ_CP045410.1|WP_152493450.1|3311138_3312200_-|polyamine-ABC-transporter-ATP-binding-protein	gnl|CDD|226361	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism].	9.86412e-163
NZ_CP045410.1|WP_152493459.1|3298301_3299867_-|2-isopropylmalate-synthase	gnl|CDD|234864	PRK00915, PRK00915, 2-isopropylmalate synthase; Validated.	0
NZ_CP045410.1|WP_152497617.1|3308383_3309415_-|extracellular-solute-binding-protein	gnl|CDD|270382	cd13664, PBP2_PotD_PotF_like_3, TThe periplasmic substrate-binding component of an uncharacterized active transport system closely related to spermidine and putrescine transporters; contains the type 2 periplasmic binding fold. This family represents the periplasmic substrate-binding domain that functions as the primary high-affinity receptors of ABC-type polyamine transport systems. Polyamine transport plays an essential role in the regulation of intracellular polyamine levels which are known to be elevated in rapidly proliferating cells and tumors. Natural polyamines are putrescine, spermindine, and spermine. They are polycations that play multiple roles in cell growth, survival and proliferation, and plant stress and disease resistance. They can interact with negatively charged molecules, such as nucleic acids, to modulate their functions. Members of this family belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	6.86572e-143
NZ_CP045410.1|WP_152497612.1|3296274_3297297_+|extracellular-solute-binding-protein	gnl|CDD|270260	cd13542, PBP2_FutA1_ilke, Substrate binding domain of ferric iron-binding protein, a member of the type 2 periplasmic binding fold superfamily. FutA1 is the periplasmic component of an ABC-type iron transporter and serves as the primary receptor in Synerchosystis species. The periplasmic iron binding protein plays an essential role in the iron uptake pathway of Gram-negative pathogenic bacteria and is critical for survival of these pathogens within the host. After binding iron with high affinity, FutA1 interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The iron- and thiamine-binding proteins belong to the PBPI2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.64289e-146
NZ_CP045410.1|WP_152497610.1|3293501_3294176_+|nitroreductase-family-protein	gnl|CDD|380313	cd02136, PnbA_NfnB-like, nitroreductase similar to Mycobacterium smegmatis NfnB. Members of this family utilize FMN as a cofactor and catalyze reduction of a variety of nitroaromatic compounds, including nitrofurans, nitrobenzens, nitrophenol, nitrobenzoate and quinones by using either NADH or NADPH as a source of reducing equivalents in an obligatory two-election transfer mechanism. The enzyme is typically a homodimer. Mycobacterium smegmatis nitroreductase NfnB plays a role in resistance to benzothiazinone.	3.6645e-30
NZ_CP045410.1|WP_152493452.1|3309441_3310248_-|ABC-transporter-permease-subunit	gnl|CDD|224098	COG1177, PotC, ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism].	1.50293e-80
NZ_CP045410.1|WP_152498286.1|3300130_3300796_+|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|181609	PRK09009, PRK09009, SDR family oxidoreductase.	3.76311e-56
NZ_CP045410.1|WP_152497607.1|3290826_3291957_+|SPFH-domain-containing-protein	gnl|CDD|372597	pfam13421, Band_7_1, SPFH domain-Band 7 family.	3.16947e-131
NZ_CP045410.1|WP_152497618.1|3310240_3311137_-|ABC-transporter-permease-subunit	gnl|CDD|224097	COG1176, PotB, ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism].	3.3366e-91
NZ_CP045410.1|WP_152497620.1|3314001_3314397_-|metallopeptidase-family-protein	gnl|CDD|240572	cd12952, MMP_ACEL2062, Minimal MMP-like domain found in Acidothermus cellulolyticus hypothetical protein ACEL2062 and similar protein. The subfamily includes an uncharacterized protein from Acidothermus cellulolyticus (ACEL2062) and its homologs from bacteria. Although its biological role remains unclear, ACEL2062 contains a minimal metalloprotease (MMP)-like domain consisting of 3-stranded mixed 2-beta sheets and a HExxHxxGxxD/S (x could be any amino acid) motif. It may belong to a superfamily of bacterial zinc metallo-peptidases, which is characterized by a conserved HExxHxxGxxD motif.	5.50713e-43
NZ_CP045410.1|WP_172978902.1|3316934_3319040_-|nitrate--and-nitrite-sensing-domain-containing-protein	gnl|CDD|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	4.08977e-56
NZ_CP045410.1|WP_152497611.1|3294186_3296079_-|acyl-CoA-synthetase	gnl|CDD|236043	PRK07529, PRK07529, AMP-binding domain protein; Validated.	0
NZ_CP045410.1|WP_152497616.1|3304330_3305989_+|NAD+-synthase	gnl|CDD|237577	PRK13981, PRK13981, NAD synthetase; Provisional.	0
NZ_CP045410.1|WP_152497622.1|3315527_3316853_+|glutamate--tRNA-ligase	gnl|CDD|183594	PRK12558, PRK12558, glutamyl-tRNA synthetase; Provisional.	0
NZ_CP045410.1|WP_152497621.1|3314436_3315348_-|MBL-fold-metallo-hydrolase	gnl|CDD|293806	cd07720, OPHC2-like_MBL-fold, Pseudomonas pseudoalcaligenes organophosphorus hydrolase C2, and related proteins; MBL-fold metallo hydrolase domain. Pseudomonas pseudoalcaligenes OPHC2 is a thermostable organophosphorus hydrolase which a broad substrate activity spectrum: it hydrolyzes various phosphotriesters, esters, and a lactone. This subgroup also includes Pseudomonas oleovorans PoOPH which exhibits high lactonase and esterase activities, and latent PTE activity. However, double mutations His250Ile/Ile263Trp switch PoOPH into an efficient and thermostable PTE. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	4.80076e-79
NZ_CP045410.1|WP_152497613.1|3297473_3298235_+|SDR-family-oxidoreductase	gnl|CDD|180993	PRK07478, PRK07478, short chain dehydrogenase; Provisional.	5.74849e-119
NZ_CP045410.1|WP_152497609.1|3292401_3293505_+|primosomal-protein-N'-(replication-factor-Y)---superfamily-II-helicase	gnl|CDD|371721	pfam11781, zf-RRN7, Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7. This is the zinc-finger at the start of transcription-binding factor that associates strongly with both Rrn6 and Rrn7 to form a complex which itself binds the TATA-binding protein and is required for transcription by the core domain of the RNA PolI promoter.	4.21963e-06
NZ_CP045410.1|WP_152497619.1|3312262_3313708_-|amidase	gnl|CDD|223232	COG0154, GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis].	2.15848e-102

Protein sequences

>NZ_CP045410.1|WP_152497614.1|3300789_3302319_+|cryptochrome/photolyase-family-protein
MVKRLILVLGDQLSNNLSALRDADKERDIVVMAEVADEASYVGHHPKKIALIFAAMRHFAEELQDDGWQVAYSRLDDDDTSKSIVGELMRRGQEHDTTEVVATRPGEWRLVEALDNAPLTVTMLPDDRFVASLDEFNTWAEGRKSLRMEYFYRDMRRKTGLMMEGDEPAGKKWNYDHENRKPASGDMLRSKPMEFTPDKITEEVLDLVEEKFGNNFGALRPFTYAVSRGQALRALDHFAKNLLDCFGDYQDAMLQDDRFLHHSLLSQYLNIGLLDPVEICTRVEEEWKAGNVPINAAEGFIRQIIGWREYVRGIYFREGPDYVTRNALGHERDLPWMYWGGETQMNCVAHAVDQTRELAYAHHIQRLMVTGNFALLAGVDPHQVHEWYLAVYHDAFEWVEAPNVIGMSQFADDGIIASKPYVSSGNYIDKMSDYCGSCAYSVKDKTGEKACPFNLLYWDFLVRHREKFSNNPRMGQMYATWDRMKDDRKDAVLKGAKRILDRLDACEIV
>NZ_CP045410.1|WP_152498286.1|3300130_3300796_+|SDR-family-NAD(P)-dependent-oxidoreductase
MKDALVIGASGGIGSALVSALEKRDVRVTGLSRSGDGLDVTDEASVEAHLGALEGEYDLVFVATGALELEGSGPEKSLKELRSEAMEAQFRVNCIGPSLVLKHSVRLLPRDRECRFAALSARVGSIGDNGLGGWYSYRTAKAAVNQMIHGGAIELARTHGQSICVALHPGTVETPLTKKFAGGHTTVTPEEAAQNLLDVLAGLTPENTGQFFDWAGEPVPW
>NZ_CP045410.1|WP_152493459.1|3298301_3299867_-|2-isopropylmalate-synthase
MTNSEQNRVVIFDTTLRDGEQSPGATMTHAEKLEIAGLLDEMGVDIIEAGFPIASEGDFRAVSEIAKNAKNSVICGLARANLKDIDRCWDAVKHASQPRIHTFIGTSPLHRAIPNLNKDEMAERIHETVTHARNLCDNVQWSPMDATRTEWDYLARVVEIAIKAGATTINIPDTVGYTAPVESADLIRRLIAEVPGADEVVFATHCHNDLGMATANSLAAVEGGARQIECTINGLGERAGNTALEEVVMAMKVRNDIIPYHTRIDSTKIMHLSRRVATVSGFQVQPNKAIVGKNAFAHESGIHQDGMLKNAETFEIMRPEDVGLTETNIVMGKHSGRAALRSKLKNLGIDLAENQLSDVFVRFKELADRKKEVFDEDLIALVTAGEDAENDRLVLKSLRVVCGTGGQAEAEMVMSIDGVETSATEQGDGPVDATFKAVRQLHPNDAHLSLYQVHAVTEGTDAQATVSVRLEEGGNIATGQSADTDTVVASAKAYINALNRLLTRRAKLGENEKEVSYKDVS
>NZ_CP045410.1|WP_152497613.1|3297473_3298235_+|SDR-family-oxidoreductase
MLLQDRSIIITGASSGIGAAAALIFAAQGARLVLGARRADMLSRIAGQINQSNGHAVAVAGDVCDPGYAQRLVDAARDAYGGLDGALNNAGTVGSGAMLADTQDAEWAEVLATNLTAGFHAARAQIPALRERGGGSLVFTGTFVGHTATLPGMGAYAASKAGLVGLVQAIAVETGGEGIRANVLMPGGTMTEMAKDAATNPETADFIAGLHALKRMAQPQEIANAALFLLSDLSSFVTGAAMLADGGNSIAKV
>NZ_CP045410.1|WP_152497612.1|3296274_3297297_+|extracellular-solute-binding-protein
MAHLTSRSLVAALALSGVAMPAVAQEVNVYSSRHYDTDDSLYEAFTEETGITVNRIEADADELIARLEAEGENSPADVLITVDAGRMARAEELDLLAAYDSQTIEDRIPDHLEHPENLWYGIAQRARIIYYDKEKVENPPQTYEELADPAWEGKICIRSSSNIYNQSLMASIIETHGEEAAKEWAQGIVNNMARDPQGGDTDQLRGIVSGECEVAVGNHYYFVRGFESDVEGLSDGIEKIGWVWPNQDDRGTHVNLSTAAMLKTAPNPENAMKLMEFFTSDTAQTNLATGNHEYPAVEDAPGTATTERLGEFKPDETTPTAAFSRNAAKAQELFNAVGWD
>NZ_CP045410.1|WP_152497611.1|3294186_3296079_-|acyl-CoA-synthetase
MTFSTRQDVIAIQQEMPWEARDVPKTVYQMLADTATAFPDRPAVSYQLLSGPMDKSQTLTWSEFHGRVCQAANLFRSLKISETDVIALVMPNCLETAIATIGAMVAGIANPINPLLEPEQIGAILRETDARVVVTLRSFPKTDVAQKMAEAVRNAPRVHTVLEVDLVRYLTPPKSWIVPLIRPKNPDNHHADVKNFNAEARKHPNTLVFKDSATDRVAAYFHTGGTTGMPKVAQHKYSGMVYNGWLGHRLLFDEHDSIMCPLPLFHVFACHVILMAMIKSGAHVVFPTPAGYRGDGVFDNFWKLLERWGTTFVITVPTATAALMQRKVNADISKVKNAFSGSAPMPLELFKRFESATGMTVIEGYGLTEATCLVSCNPPTGEKKVGSVGVPLPYTDVKIYKTDGTECGPDEVGEIGIANPGVFAGNTYTEVAKNKDLYHHEVYLRTGDLGRIDDDGYLWITGRAKDLIIRGGHNIDPADIEEALMAHAEVAGAGAIGQPDAHSGELPCAYVELVSGGSVDSAALLEHCKVHVHERAAIPKYIEVLDELPKTAVGKVFKPDLRKRAITRVYNAALADAGINAEVTEVIDDKKRGLVACLSKTGDADEAAISQCLGEFTRPWIWADAKPKAD
>NZ_CP045410.1|WP_152497610.1|3293501_3294176_+|nitroreductase-family-protein
MSGDGDALKRLMQARYSCRAFRPDPVADAVIERIVDTARHTASWNNTQPWELLVTRGTETEAFRQALLSEVRTGKPGPDMDWPESYPGELGERRRTCGYALYNAVGIAREDREARARQSMRNFELFDAPHVAILHIPQVLGPYGALDAGGFLTAFMLAATAEGLGTIAQAAVAAYPHVIRRQFGLPEHHAILCAISFGYADETHPVNQYRTEREDVGAILSFKG
>NZ_CP045410.1|WP_152497609.1|3292401_3293505_+|primosomal-protein-N'-(replication-factor-Y)---superfamily-II-helicase
MLDSPTVDQEHRFPCDQCGADFRFDPQAGKLICDHCGNEAEMEQAGPWAAPLKELDFGAAVKGTLDASEIEETRVATCPNCAAQVEFDATVHARECPFCATPVVTDTGTHRHIKPRGVLPFKVDEPAARGAMTDWLGRLWFAPNGLQEYARKGRKMQGIYVPYWTYDADTRSSYTGERGTVYYETKTVMRDGKRQQVQVAKVRWTPVRGRVARFFDDVLVLASKTLPKRYTDALEPWELGELQPYSPEFLAGFRAEGYQVTLEDGFVQARQIMDARIARDVRFDIGGDRQRIHSIDTAVSDVTFKHILLPVWLAAYKYRGETYRFVVNGRTGKVQGERPYSAIKIAIAVVIGIIVAAAVGYGVAISQ
>NZ_CP045410.1|WP_172978901.1|3291953_3292397_+|hypothetical-protein
MRAFKARRLATQVLHWTTGVLLYLLLSVDDRIFGLLGWAFVVSGGALCVLWLCFGLLNKGPGPALEGVLRTAHPWLSRGMYVLLGWAVVALAAGALERPLPGPEARTALLVLGAAALFHAIFHLWRHTALRDGALRRIIPVKLHKYL
>NZ_CP045410.1|WP_152497607.1|3290826_3291957_+|SPFH-domain-containing-protein
MGIFDFLSGEFIDVIHWVDDTRDTMVWRFERHGHEIKYGAKLTVREGQAAVFVHEGQLADVFTPGLYMLETNNMPIMTTLQHWDHGFQSPFKSEIYFVNTTRFTDLKWGTKNPIMLRDPEFGPTRIRAFGTYSTRVTDPAKFLTEIVGTDGEFTMDEISYQVRNIIVQSFSRIIAGSGIPVLDMAANTADLGKLVAAEISAVVADYGLTIPEFYIENISLPPAVEEALDKRTSMGLAGDLGKFTQYSAAEAMTAAAKNPGGAGGGMGAGIGAGLGMAMAGQMAGQGGPWGQAAHQPSSAAAPAPPPPPVEHVWHIAENGQTHGPYSKAALGRMASDGKLTRDSHVWTAGQDGWLKAGDVQELAQLFTILPPPPPGA
>NZ_CP045410.1|WP_152497616.1|3304330_3305989_+|NAD+-synthase
MADRFRVTLAQLNATVGDLGGNAALARKAWEAGREAGADLVALPEMFITGYNTQDLIRKPVFHQAAIAKIEDLAKECAVGPALAIGGPALEGAELYNAYYILKGGSITACVLKHHLPNETVFDEVRLYASGDVMGPYAVDGVRIGSPICEDSWHDDVPETLAETGAEFLLVPNGSPYYRGKLAHRHQLMVNRVVETGLPLIYLNLVGAQDDQVFDGGTFALNPGGGLAVQMPLFEEDIAHVDLVRGDDGWRIETKALAHIPDTLESDYHAMVLALRDYMRKTGFGKVLLGLSGGVDSAIVATIAVDALGAENVRCVMLPSEYTSQGSLDDAKACAKALGARYDFVPIAEGRAAITNTLAPLFEGTEPGITEENIQSRLRGLLLMALSNKFGEMLLTTGNKSEVAVGYATIYGDMAGGYNPIKDLYKTRVFDVCRWRNANHRDWMMGPGGEVIPETIIEKPPSAELRADQKDSDSLPDYPVLDGILQILVDEDGSIEDCVKAGYSRADAARVEHLIYISEYKRFQSAPGTRLSKRAFWLDRRYPIVNRWRDGG
>NZ_CP045410.1|WP_152497617.1|3308383_3309415_-|extracellular-solute-binding-protein
MTMKTYLTTTVATIALAGAAHAEGSLNIYNWGNYTSPEMIEKFEQEFDVDVTITDYDSNTTALAKIEAGGHGFDIVVPTHSYMGVYIDKGLLMKPGIPEMENYGNISEQWKNVEWDPNREYSVPWQWGTTGIAVNKSAYDGDINTSSIFLDPPEELVGKVNVVPEMQDVMNLTLFYVGGEPCTTDKEMLKKARDVLIEAKPKWMSMDYGMTEKLSNGDVMASVNWNGSTFRARNNNEDVSYGYPKEGYPVWMDSAAILADAQNVENAKLFLNFIMDPENAAMLSDFARYANGIDGSEEFMPEDMRSAPEIVVPEDLKAAGQFTTACPAEAQEFYTAIWTELQK
>NZ_CP045410.1|WP_152493452.1|3309441_3310248_-|ABC-transporter-permease-subunit
MAKGKSFSVTTLPGFTAIALTTFVLLYAPIVTMVIYSFNDSQSVALWGGFSTRWYVEAWDNTQVQEATVRSLVIAVSAAFISTTVATMAALGTTRRGRFKGQTLIYVMINQPLMVPEIVTAVALLIFFASIKVATGYTGLAYLILAHSAFCVPFAYLPIRARLEGMDLALETAASDLYARPWQTFRHVTLPLMMPGIAAGAMLAFVISLDDVIITEFVKSAGQDTLPTYMLGQLRRVVTPEVNAISTALLALTVLLLTAFFILNRKRD
>NZ_CP045410.1|WP_152497618.1|3310240_3311137_-|ABC-transporter-permease-subunit
MAGTTHGSGRTGWILSIPALILLALGAAGPLLIVVVYAFLEPGEYSGVVWDFTTEAWFRVFFERDIFDDTVTFADAHLTIFWRSVKLSVLTTLIAFAIGFPTAWFIATRPPNKRGFWLFLITIPFWTNLLIRTFAIMEVVRNQGLLNSFLMNLGIIDQPLQILYTDTAVLIGMAYVYLPLMVLPLFAAIDRFDFRLVEAGYDLYATRMKVLRRVILPIVKPGIVAGSILVFVPSLGAYVTPRILSGGKNMMIGNFIELQFGQGRNWPLGAALSLLLLMIVLVALLAYVRVTSRDETNG
>NZ_CP045410.1|WP_152493450.1|3311138_3312200_-|polyamine-ABC-transporter-ATP-binding-protein
MTEAAVEARSARKEYGAGEKKVRALNDVSVVINKGEFFTLLGPSGCGKTTLLRLIAGFESPTAGMILLGARDISTMAPYDRPVNTVFQSYALFPHLSVADNIGFGLTMQGTPKAQVQARVAEMLALVKLEAFAARKPQQLSGGQQQRVALARALAPAPEVLLLDEPLSALDLKLRKEMQLELKRLQTETGITFVFVTHDQEEALTMSDRIGVMRDGSILQIGGPREIYNKPVNRFVADFIGETNVLIGTVEQGGVRLPTGDVIAVDNLDAATQGTKVSLAVRPEQVRIGDGALQGRVAETVYFGTDTHCHLRMSDDTEVVARMQSPPSGDTGLQEGQTVAFDFVPGAVRVLED
>NZ_CP045410.1|WP_152497619.1|3312262_3313708_-|amidase
MDDYRAHDMTSLAGLVAKGEVTPDDLLDTALARMHAVNPALNAVVHDYSDTARRMIADGLPKGPLTGVPFLLKDMGAESTRHPASLGSRLLANTSYRMNSTIYDRLEASGLVTFGRTAAPEGGVGAATEAAVYGGPTRNPWDTSRTPGGSSGGSGAAVAAGIVPGAHGSDGGGSIRIPASNCGLVGFKPTRAMVPDGPYAGEGWAGMAIEGFLTRSVRDTALLLDIVCGPDLGAPYVAPPMPCTFMESLDRPNGPLRIALCDTTLTGEAIHPECQVAVQDAAALLHDMGHHVTQARPAADTTGMMHAWTKIVACGTASWVRAALAKQGRELRQGDIEGVARGAVEYAKTISGADYLDAVETVHAYGRQMAAFFVDHDILLTPTMAEPPAAIGRFAHDTEDYVAYRVGEGGIFAYSPYTAAFNATGQPAVSLPLCRGADGLPIGIHLAARFGADTALMSLCADIERARPWFDQIPALPGIDT
>NZ_CP045410.1|WP_152497620.1|3314001_3314397_-|metallopeptidase-family-protein
MPAPDTSLDWMEDVARRTVAGFPQAFAEAARAVAIHVADWPDREMLDSLDMTDPVELTGLYDGIPMTEKSVFDQPTGPDIVWLFRQPILAEWRDRGDVDLADLVAHVTVHEFAHHFGWSDDDIASIDRWWE
>NZ_CP045410.1|WP_152497621.1|3314436_3315348_-|MBL-fold-metallo-hydrolase
MSTLSRRTFLASATALSAAPALPAWATAPMLGAATPPFRRFKLGAFEVTTLLAGEATRPDPHTIFGLNVDEAEFTAVSEAAMIPTDQAQFFFTPTVVNTGSELVLFDTGLNAEGTTAALDAAGYSADMIDTVVITHMHGDHIGGLMEGDAPTFANADYVTGSAEFDHWSAAGDDNFEAKVRPLAEQFTMIGDGDAGFSGHTAMAAFGHTPGHMVHLIESEGESLMIAADFANHYVWSLAHPDWEVKFDMDKAAAAQTRKTILDMLAAEKMPFIGYHMPWPATGFVEKTDSGYAYVPSSYQLRL
>NZ_CP045410.1|WP_152497622.1|3315527_3316853_+|glutamate--tRNA-ligase
MTTTRFAPSPTGYIHIGNLRTALMNFLIARKNGGTFILRIDDTDPERSKQEYVDAIKQDLEWLGLTWDRVERQSERLDRYAQAAETLRGMGRFYEAFETPTELDLKRKKQLNMGKPPVYDRAALGLSDEQKDALRAERGDGVWRFKLDHERIEWDDGILGDISIDAASVSDPVLIRGDGQVLYTLASVVDDTEMGVTHVVRGSDHVTNTATQIQIIEALGGTVPSFAHHSLLTGPQGESLSKRLGTLSLRDLRAQGVEPMALLSLMARLGSADPVELRSEMAELIEGFDISRFGSAPTKFDANDLFPLTARVLQGRDFADVKAHILGLGVPEDQAERFWSVTRENITTLHDLEPWWVMFRDGAEPVIDDEDREFVAQALALLPEGPHDGDTWGQWTNAVKEETGRKGKGLFMPLRKALTGQNHGPDMSQVLPLLQVIRAKG
>NZ_CP045410.1|WP_172978902.1|3316934_3319040_-|nitrate--and-nitrite-sensing-domain-containing-protein
MRLRVVMFLVIAPLFAAVGYLTSVEVAQKRADAGQAETSRILAHESAIVGALVHELQKERGFSAGLIASRGANFRSDLARQRTDSDAAIAAFAAEVSALRRARPPEIASVNTRLDQLEDMRKQVDAFGLAVPDMAAFYTETITHLLELERPVAARTTRGETNALLEARTLLSAAKEAAGLERAMGATGLGSGFRPAVFNRYLRLNGAQEALLTEAAGTLEDPEWLARIRASDASATIRSARDRILAGTRTRNFDGLTAPEWFAISTAWIDLLRAEELKLFEAVRVKSAEIEATADTTLKRFAIFGSVLAVSVLAFAVFAFERMIARIKYLISVINKFTGGDFSVYIDGIDSKDELGQMASAIFHFKQETIEMRKGAEALKADQERIKAEQDQVVTALRDGLNRLSDGDLAQRFDNPFPQEYESLRHDFNTTVSRLNDALCKVVDATRSIRSGSGALERSSGDLSFKAEEQAQNVRNTADAVKEVTSSVRAASLGAGEVQQTTQAAKNAALESDPVVRQAVDAMEEISGSSEQIAQIIVLIEDIAFQTNLLALNAGVEAARAGDAGRGFAVVASEVRALAQRSTEAAMQIKTLIGNSSLQVKNGVELVNEAGTALKSILERVAQIDKLVADMAKATEEQASELENINTTVTRVDSVTQETATMAAEARTTCEDLNTYAGHLEQLVGQFSLTRPERDGLPSAA

Crispr_ID: NZ_CP045410_3

• CRISPR_ID: NZ_CP045410_3
• CRISPR_location: 3302938-3303239
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of NZ_CP045410_3

Consensus_repeat	Method
CTCGCCTTCGTAGACATCGCCGTTG	CRISPRCasFinder

spacers of NZ_CP045410_3

>3.1|3302963|29|NZ_CP045410|CRISPRCasFinder
GGCATGGTGATCTTGCCGGTGCCGTGGCG
>3.2|3303017|59|NZ_CP045410|CRISPRCasFinder
TAGACCGTGCCGTCGGCATAGGTGGCGGTGCCCTGGCCGTGGCGTTGACCATCGCGCCA
>3.3|3303101|44|NZ_CP045410|CRISPRCasFinder
GGATAGGTCATCACGCCCTGGCCGTGGTTCTTGGCGTTCTGGAA
>3.4|3303170|44|NZ_CP045410|CRISPRCasFinder
GGATAGGTCGCCTTGCCTTGCCCGTCGATCACGCCGCCCGACCA

CRISPR arrays and Neighbor proteins around NZ_CP045410_3

CRISPR arrays

The CRISPR arrays of NZ_CP045410_3

>merge|NZ_CP045410|3|3302938-3303239|CRISPRCasFinder
CTCGCCTTCGTAGACGAAGCCGTCCGGCATGGTGATCTTGCCGGTGCCGTGGCGCTGGCCATCGACGAATTCGCCTTCGTAGACCGTGCCGTCGGCATAGGTGGCGGTGCCCTGGCCGTGGCGTTGACCATCGCGCCATGCGCCTTCGTAGCGGTAGCCGTCGGGATAGGTCATCACGCCCTGGCCGTGGTTCTTGGCGTTCTGGAATTCGCCTTCGTAGACCAGACCGTTGGGATAGGTCGCCTTGCCTTGCCCGTCGATCACGCCGCCCGACCATTCGCCCTCGTAGGTGGCGCCGTCGG

>NZ_CP045410|3|3|3302938-3303239|CRISPRCasFinder
CTCGCCTTCGTAGACGAAGCCGTCC	GGCATGGTGATCTTGCCGGTGCCGTGGCG
CTGGCCATCGACGAATTCGCCTTCG	TAGACCGTGCCGTCGGCATAGGTGGCGGTGCCCTGGCCGTGGCGTTGACCATCGCGCCA
TGCGCCTTCGTAGCGGTAGCCGTCG	GGATAGGTCATCACGCCCTGGCCGTGGTTCTTGGCGTTCTGGAA
TTCGCCTTCGTAGACCAGACCGTTG	GGATAGGTCGCCTTGCCTTGCCCGTCGATCACGCCGCCCGACCA
TTCGCCCTCGTAGGTGGCGCCGTCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045410.1|WP_152497614.1|3300789_3302319_+|cryptochrome/photolyase-family-protein	unknown	unknown	gnl|CDD|225588
NZ_CP045410.1|WP_152497621.1|3314436_3315348_-|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293806
NZ_CP045410.1|WP_152493450.1|3311138_3312200_-|polyamine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|226361
NZ_CP045410.1|WP_152493459.1|3298301_3299867_-|2-isopropylmalate-synthase	unknown	unknown	gnl|CDD|234864
NZ_CP045410.1|WP_152497617.1|3308383_3309415_-|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|270382
NZ_CP045410.1|WP_152497612.1|3296274_3297297_+|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|270260
NZ_CP045410.1|WP_152497610.1|3293501_3294176_+|nitroreductase-family-protein	unknown	unknown	gnl|CDD|380313
NZ_CP045410.1|WP_152493452.1|3309441_3310248_-|ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|224098
NZ_CP045410.1|WP_152498286.1|3300130_3300796_+|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|181609
NZ_CP045410.1|WP_152497607.1|3290826_3291957_+|SPFH-domain-containing-protein	unknown	unknown	gnl|CDD|372597
NZ_CP045410.1|WP_152497618.1|3310240_3311137_-|ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|224097
NZ_CP045410.1|WP_152497620.1|3314001_3314397_-|metallopeptidase-family-protein	unknown	unknown	gnl|CDD|240572
NZ_CP045410.1|WP_172978902.1|3316934_3319040_-|nitrate--and-nitrite-sensing-domain-containing-protein	unknown	unknown	gnl|CDD|214599
NZ_CP045410.1|WP_152497611.1|3294186_3296079_-|acyl-CoA-synthetase	unknown	unknown	gnl|CDD|236043
NZ_CP045410.1|WP_152497616.1|3304330_3305989_+|NAD+-synthase	unknown	unknown	gnl|CDD|237577
NZ_CP045410.1|WP_152497622.1|3315527_3316853_+|glutamate--tRNA-ligase	unknown	unknown	gnl|CDD|183594
NZ_CP045410.1|WP_152497619.1|3312262_3313708_-|amidase	unknown	unknown	gnl|CDD|223232
NZ_CP045410.1|WP_152497613.1|3297473_3298235_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|180993
NZ_CP045410.1|WP_152497609.1|3292401_3293505_+|primosomal-protein-N'-(replication-factor-Y)---superfamily-II-helicase	unknown	unknown	gnl|CDD|371721
NZ_CP045410.1|WP_172978901.1|3291953_3292397_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP045410.1|WP_152497614.1|3300789_3302319_+|cryptochrome/photolyase-family-protein	gnl|CDD|225588	COG3046, COG3046, Uncharacterized protein related to deoxyribodipyrimidine photolyase [General function prediction only].	0
NZ_CP045410.1|WP_152493450.1|3311138_3312200_-|polyamine-ABC-transporter-ATP-binding-protein	gnl|CDD|226361	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism].	9.86412e-163
NZ_CP045410.1|WP_152493459.1|3298301_3299867_-|2-isopropylmalate-synthase	gnl|CDD|234864	PRK00915, PRK00915, 2-isopropylmalate synthase; Validated.	0
NZ_CP045410.1|WP_152497617.1|3308383_3309415_-|extracellular-solute-binding-protein	gnl|CDD|270382	cd13664, PBP2_PotD_PotF_like_3, TThe periplasmic substrate-binding component of an uncharacterized active transport system closely related to spermidine and putrescine transporters; contains the type 2 periplasmic binding fold. This family represents the periplasmic substrate-binding domain that functions as the primary high-affinity receptors of ABC-type polyamine transport systems. Polyamine transport plays an essential role in the regulation of intracellular polyamine levels which are known to be elevated in rapidly proliferating cells and tumors. Natural polyamines are putrescine, spermindine, and spermine. They are polycations that play multiple roles in cell growth, survival and proliferation, and plant stress and disease resistance. They can interact with negatively charged molecules, such as nucleic acids, to modulate their functions. Members of this family belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	6.86572e-143
NZ_CP045410.1|WP_152497612.1|3296274_3297297_+|extracellular-solute-binding-protein	gnl|CDD|270260	cd13542, PBP2_FutA1_ilke, Substrate binding domain of ferric iron-binding protein, a member of the type 2 periplasmic binding fold superfamily. FutA1 is the periplasmic component of an ABC-type iron transporter and serves as the primary receptor in Synerchosystis species. The periplasmic iron binding protein plays an essential role in the iron uptake pathway of Gram-negative pathogenic bacteria and is critical for survival of these pathogens within the host. After binding iron with high affinity, FutA1 interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The iron- and thiamine-binding proteins belong to the PBPI2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.64289e-146
NZ_CP045410.1|WP_152497610.1|3293501_3294176_+|nitroreductase-family-protein	gnl|CDD|380313	cd02136, PnbA_NfnB-like, nitroreductase similar to Mycobacterium smegmatis NfnB. Members of this family utilize FMN as a cofactor and catalyze reduction of a variety of nitroaromatic compounds, including nitrofurans, nitrobenzens, nitrophenol, nitrobenzoate and quinones by using either NADH or NADPH as a source of reducing equivalents in an obligatory two-election transfer mechanism. The enzyme is typically a homodimer. Mycobacterium smegmatis nitroreductase NfnB plays a role in resistance to benzothiazinone.	3.6645e-30
NZ_CP045410.1|WP_152493452.1|3309441_3310248_-|ABC-transporter-permease-subunit	gnl|CDD|224098	COG1177, PotC, ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism].	1.50293e-80
NZ_CP045410.1|WP_152498286.1|3300130_3300796_+|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|181609	PRK09009, PRK09009, SDR family oxidoreductase.	3.76311e-56
NZ_CP045410.1|WP_152497607.1|3290826_3291957_+|SPFH-domain-containing-protein	gnl|CDD|372597	pfam13421, Band_7_1, SPFH domain-Band 7 family.	3.16947e-131
NZ_CP045410.1|WP_152497618.1|3310240_3311137_-|ABC-transporter-permease-subunit	gnl|CDD|224097	COG1176, PotB, ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism].	3.3366e-91
NZ_CP045410.1|WP_152497620.1|3314001_3314397_-|metallopeptidase-family-protein	gnl|CDD|240572	cd12952, MMP_ACEL2062, Minimal MMP-like domain found in Acidothermus cellulolyticus hypothetical protein ACEL2062 and similar protein. The subfamily includes an uncharacterized protein from Acidothermus cellulolyticus (ACEL2062) and its homologs from bacteria. Although its biological role remains unclear, ACEL2062 contains a minimal metalloprotease (MMP)-like domain consisting of 3-stranded mixed 2-beta sheets and a HExxHxxGxxD/S (x could be any amino acid) motif. It may belong to a superfamily of bacterial zinc metallo-peptidases, which is characterized by a conserved HExxHxxGxxD motif.	5.50713e-43
NZ_CP045410.1|WP_172978902.1|3316934_3319040_-|nitrate--and-nitrite-sensing-domain-containing-protein	gnl|CDD|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	4.08977e-56
NZ_CP045410.1|WP_152497611.1|3294186_3296079_-|acyl-CoA-synthetase	gnl|CDD|236043	PRK07529, PRK07529, AMP-binding domain protein; Validated.	0
NZ_CP045410.1|WP_152497616.1|3304330_3305989_+|NAD+-synthase	gnl|CDD|237577	PRK13981, PRK13981, NAD synthetase; Provisional.	0
NZ_CP045410.1|WP_152497622.1|3315527_3316853_+|glutamate--tRNA-ligase	gnl|CDD|183594	PRK12558, PRK12558, glutamyl-tRNA synthetase; Provisional.	0
NZ_CP045410.1|WP_152497621.1|3314436_3315348_-|MBL-fold-metallo-hydrolase	gnl|CDD|293806	cd07720, OPHC2-like_MBL-fold, Pseudomonas pseudoalcaligenes organophosphorus hydrolase C2, and related proteins; MBL-fold metallo hydrolase domain. Pseudomonas pseudoalcaligenes OPHC2 is a thermostable organophosphorus hydrolase which a broad substrate activity spectrum: it hydrolyzes various phosphotriesters, esters, and a lactone. This subgroup also includes Pseudomonas oleovorans PoOPH which exhibits high lactonase and esterase activities, and latent PTE activity. However, double mutations His250Ile/Ile263Trp switch PoOPH into an efficient and thermostable PTE. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	4.80076e-79
NZ_CP045410.1|WP_152497613.1|3297473_3298235_+|SDR-family-oxidoreductase	gnl|CDD|180993	PRK07478, PRK07478, short chain dehydrogenase; Provisional.	5.74849e-119
NZ_CP045410.1|WP_152497609.1|3292401_3293505_+|primosomal-protein-N'-(replication-factor-Y)---superfamily-II-helicase	gnl|CDD|371721	pfam11781, zf-RRN7, Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7. This is the zinc-finger at the start of transcription-binding factor that associates strongly with both Rrn6 and Rrn7 to form a complex which itself binds the TATA-binding protein and is required for transcription by the core domain of the RNA PolI promoter.	4.21963e-06
NZ_CP045410.1|WP_152497619.1|3312262_3313708_-|amidase	gnl|CDD|223232	COG0154, GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis].	2.15848e-102

Protein sequences

>NZ_CP045410.1|WP_152497614.1|3300789_3302319_+|cryptochrome/photolyase-family-protein
MVKRLILVLGDQLSNNLSALRDADKERDIVVMAEVADEASYVGHHPKKIALIFAAMRHFAEELQDDGWQVAYSRLDDDDTSKSIVGELMRRGQEHDTTEVVATRPGEWRLVEALDNAPLTVTMLPDDRFVASLDEFNTWAEGRKSLRMEYFYRDMRRKTGLMMEGDEPAGKKWNYDHENRKPASGDMLRSKPMEFTPDKITEEVLDLVEEKFGNNFGALRPFTYAVSRGQALRALDHFAKNLLDCFGDYQDAMLQDDRFLHHSLLSQYLNIGLLDPVEICTRVEEEWKAGNVPINAAEGFIRQIIGWREYVRGIYFREGPDYVTRNALGHERDLPWMYWGGETQMNCVAHAVDQTRELAYAHHIQRLMVTGNFALLAGVDPHQVHEWYLAVYHDAFEWVEAPNVIGMSQFADDGIIASKPYVSSGNYIDKMSDYCGSCAYSVKDKTGEKACPFNLLYWDFLVRHREKFSNNPRMGQMYATWDRMKDDRKDAVLKGAKRILDRLDACEIV
>NZ_CP045410.1|WP_152498286.1|3300130_3300796_+|SDR-family-NAD(P)-dependent-oxidoreductase
MKDALVIGASGGIGSALVSALEKRDVRVTGLSRSGDGLDVTDEASVEAHLGALEGEYDLVFVATGALELEGSGPEKSLKELRSEAMEAQFRVNCIGPSLVLKHSVRLLPRDRECRFAALSARVGSIGDNGLGGWYSYRTAKAAVNQMIHGGAIELARTHGQSICVALHPGTVETPLTKKFAGGHTTVTPEEAAQNLLDVLAGLTPENTGQFFDWAGEPVPW
>NZ_CP045410.1|WP_152493459.1|3298301_3299867_-|2-isopropylmalate-synthase
MTNSEQNRVVIFDTTLRDGEQSPGATMTHAEKLEIAGLLDEMGVDIIEAGFPIASEGDFRAVSEIAKNAKNSVICGLARANLKDIDRCWDAVKHASQPRIHTFIGTSPLHRAIPNLNKDEMAERIHETVTHARNLCDNVQWSPMDATRTEWDYLARVVEIAIKAGATTINIPDTVGYTAPVESADLIRRLIAEVPGADEVVFATHCHNDLGMATANSLAAVEGGARQIECTINGLGERAGNTALEEVVMAMKVRNDIIPYHTRIDSTKIMHLSRRVATVSGFQVQPNKAIVGKNAFAHESGIHQDGMLKNAETFEIMRPEDVGLTETNIVMGKHSGRAALRSKLKNLGIDLAENQLSDVFVRFKELADRKKEVFDEDLIALVTAGEDAENDRLVLKSLRVVCGTGGQAEAEMVMSIDGVETSATEQGDGPVDATFKAVRQLHPNDAHLSLYQVHAVTEGTDAQATVSVRLEEGGNIATGQSADTDTVVASAKAYINALNRLLTRRAKLGENEKEVSYKDVS
>NZ_CP045410.1|WP_152497613.1|3297473_3298235_+|SDR-family-oxidoreductase
MLLQDRSIIITGASSGIGAAAALIFAAQGARLVLGARRADMLSRIAGQINQSNGHAVAVAGDVCDPGYAQRLVDAARDAYGGLDGALNNAGTVGSGAMLADTQDAEWAEVLATNLTAGFHAARAQIPALRERGGGSLVFTGTFVGHTATLPGMGAYAASKAGLVGLVQAIAVETGGEGIRANVLMPGGTMTEMAKDAATNPETADFIAGLHALKRMAQPQEIANAALFLLSDLSSFVTGAAMLADGGNSIAKV
>NZ_CP045410.1|WP_152497612.1|3296274_3297297_+|extracellular-solute-binding-protein
MAHLTSRSLVAALALSGVAMPAVAQEVNVYSSRHYDTDDSLYEAFTEETGITVNRIEADADELIARLEAEGENSPADVLITVDAGRMARAEELDLLAAYDSQTIEDRIPDHLEHPENLWYGIAQRARIIYYDKEKVENPPQTYEELADPAWEGKICIRSSSNIYNQSLMASIIETHGEEAAKEWAQGIVNNMARDPQGGDTDQLRGIVSGECEVAVGNHYYFVRGFESDVEGLSDGIEKIGWVWPNQDDRGTHVNLSTAAMLKTAPNPENAMKLMEFFTSDTAQTNLATGNHEYPAVEDAPGTATTERLGEFKPDETTPTAAFSRNAAKAQELFNAVGWD
>NZ_CP045410.1|WP_152497611.1|3294186_3296079_-|acyl-CoA-synthetase
MTFSTRQDVIAIQQEMPWEARDVPKTVYQMLADTATAFPDRPAVSYQLLSGPMDKSQTLTWSEFHGRVCQAANLFRSLKISETDVIALVMPNCLETAIATIGAMVAGIANPINPLLEPEQIGAILRETDARVVVTLRSFPKTDVAQKMAEAVRNAPRVHTVLEVDLVRYLTPPKSWIVPLIRPKNPDNHHADVKNFNAEARKHPNTLVFKDSATDRVAAYFHTGGTTGMPKVAQHKYSGMVYNGWLGHRLLFDEHDSIMCPLPLFHVFACHVILMAMIKSGAHVVFPTPAGYRGDGVFDNFWKLLERWGTTFVITVPTATAALMQRKVNADISKVKNAFSGSAPMPLELFKRFESATGMTVIEGYGLTEATCLVSCNPPTGEKKVGSVGVPLPYTDVKIYKTDGTECGPDEVGEIGIANPGVFAGNTYTEVAKNKDLYHHEVYLRTGDLGRIDDDGYLWITGRAKDLIIRGGHNIDPADIEEALMAHAEVAGAGAIGQPDAHSGELPCAYVELVSGGSVDSAALLEHCKVHVHERAAIPKYIEVLDELPKTAVGKVFKPDLRKRAITRVYNAALADAGINAEVTEVIDDKKRGLVACLSKTGDADEAAISQCLGEFTRPWIWADAKPKAD
>NZ_CP045410.1|WP_152497610.1|3293501_3294176_+|nitroreductase-family-protein
MSGDGDALKRLMQARYSCRAFRPDPVADAVIERIVDTARHTASWNNTQPWELLVTRGTETEAFRQALLSEVRTGKPGPDMDWPESYPGELGERRRTCGYALYNAVGIAREDREARARQSMRNFELFDAPHVAILHIPQVLGPYGALDAGGFLTAFMLAATAEGLGTIAQAAVAAYPHVIRRQFGLPEHHAILCAISFGYADETHPVNQYRTEREDVGAILSFKG
>NZ_CP045410.1|WP_152497609.1|3292401_3293505_+|primosomal-protein-N'-(replication-factor-Y)---superfamily-II-helicase
MLDSPTVDQEHRFPCDQCGADFRFDPQAGKLICDHCGNEAEMEQAGPWAAPLKELDFGAAVKGTLDASEIEETRVATCPNCAAQVEFDATVHARECPFCATPVVTDTGTHRHIKPRGVLPFKVDEPAARGAMTDWLGRLWFAPNGLQEYARKGRKMQGIYVPYWTYDADTRSSYTGERGTVYYETKTVMRDGKRQQVQVAKVRWTPVRGRVARFFDDVLVLASKTLPKRYTDALEPWELGELQPYSPEFLAGFRAEGYQVTLEDGFVQARQIMDARIARDVRFDIGGDRQRIHSIDTAVSDVTFKHILLPVWLAAYKYRGETYRFVVNGRTGKVQGERPYSAIKIAIAVVIGIIVAAAVGYGVAISQ
>NZ_CP045410.1|WP_172978901.1|3291953_3292397_+|hypothetical-protein
MRAFKARRLATQVLHWTTGVLLYLLLSVDDRIFGLLGWAFVVSGGALCVLWLCFGLLNKGPGPALEGVLRTAHPWLSRGMYVLLGWAVVALAAGALERPLPGPEARTALLVLGAAALFHAIFHLWRHTALRDGALRRIIPVKLHKYL
>NZ_CP045410.1|WP_152497607.1|3290826_3291957_+|SPFH-domain-containing-protein
MGIFDFLSGEFIDVIHWVDDTRDTMVWRFERHGHEIKYGAKLTVREGQAAVFVHEGQLADVFTPGLYMLETNNMPIMTTLQHWDHGFQSPFKSEIYFVNTTRFTDLKWGTKNPIMLRDPEFGPTRIRAFGTYSTRVTDPAKFLTEIVGTDGEFTMDEISYQVRNIIVQSFSRIIAGSGIPVLDMAANTADLGKLVAAEISAVVADYGLTIPEFYIENISLPPAVEEALDKRTSMGLAGDLGKFTQYSAAEAMTAAAKNPGGAGGGMGAGIGAGLGMAMAGQMAGQGGPWGQAAHQPSSAAAPAPPPPPVEHVWHIAENGQTHGPYSKAALGRMASDGKLTRDSHVWTAGQDGWLKAGDVQELAQLFTILPPPPPGA
>NZ_CP045410.1|WP_152497616.1|3304330_3305989_+|NAD+-synthase
MADRFRVTLAQLNATVGDLGGNAALARKAWEAGREAGADLVALPEMFITGYNTQDLIRKPVFHQAAIAKIEDLAKECAVGPALAIGGPALEGAELYNAYYILKGGSITACVLKHHLPNETVFDEVRLYASGDVMGPYAVDGVRIGSPICEDSWHDDVPETLAETGAEFLLVPNGSPYYRGKLAHRHQLMVNRVVETGLPLIYLNLVGAQDDQVFDGGTFALNPGGGLAVQMPLFEEDIAHVDLVRGDDGWRIETKALAHIPDTLESDYHAMVLALRDYMRKTGFGKVLLGLSGGVDSAIVATIAVDALGAENVRCVMLPSEYTSQGSLDDAKACAKALGARYDFVPIAEGRAAITNTLAPLFEGTEPGITEENIQSRLRGLLLMALSNKFGEMLLTTGNKSEVAVGYATIYGDMAGGYNPIKDLYKTRVFDVCRWRNANHRDWMMGPGGEVIPETIIEKPPSAELRADQKDSDSLPDYPVLDGILQILVDEDGSIEDCVKAGYSRADAARVEHLIYISEYKRFQSAPGTRLSKRAFWLDRRYPIVNRWRDGG
>NZ_CP045410.1|WP_152497617.1|3308383_3309415_-|extracellular-solute-binding-protein
MTMKTYLTTTVATIALAGAAHAEGSLNIYNWGNYTSPEMIEKFEQEFDVDVTITDYDSNTTALAKIEAGGHGFDIVVPTHSYMGVYIDKGLLMKPGIPEMENYGNISEQWKNVEWDPNREYSVPWQWGTTGIAVNKSAYDGDINTSSIFLDPPEELVGKVNVVPEMQDVMNLTLFYVGGEPCTTDKEMLKKARDVLIEAKPKWMSMDYGMTEKLSNGDVMASVNWNGSTFRARNNNEDVSYGYPKEGYPVWMDSAAILADAQNVENAKLFLNFIMDPENAAMLSDFARYANGIDGSEEFMPEDMRSAPEIVVPEDLKAAGQFTTACPAEAQEFYTAIWTELQK
>NZ_CP045410.1|WP_152493452.1|3309441_3310248_-|ABC-transporter-permease-subunit
MAKGKSFSVTTLPGFTAIALTTFVLLYAPIVTMVIYSFNDSQSVALWGGFSTRWYVEAWDNTQVQEATVRSLVIAVSAAFISTTVATMAALGTTRRGRFKGQTLIYVMINQPLMVPEIVTAVALLIFFASIKVATGYTGLAYLILAHSAFCVPFAYLPIRARLEGMDLALETAASDLYARPWQTFRHVTLPLMMPGIAAGAMLAFVISLDDVIITEFVKSAGQDTLPTYMLGQLRRVVTPEVNAISTALLALTVLLLTAFFILNRKRD
>NZ_CP045410.1|WP_152497618.1|3310240_3311137_-|ABC-transporter-permease-subunit
MAGTTHGSGRTGWILSIPALILLALGAAGPLLIVVVYAFLEPGEYSGVVWDFTTEAWFRVFFERDIFDDTVTFADAHLTIFWRSVKLSVLTTLIAFAIGFPTAWFIATRPPNKRGFWLFLITIPFWTNLLIRTFAIMEVVRNQGLLNSFLMNLGIIDQPLQILYTDTAVLIGMAYVYLPLMVLPLFAAIDRFDFRLVEAGYDLYATRMKVLRRVILPIVKPGIVAGSILVFVPSLGAYVTPRILSGGKNMMIGNFIELQFGQGRNWPLGAALSLLLLMIVLVALLAYVRVTSRDETNG
>NZ_CP045410.1|WP_152493450.1|3311138_3312200_-|polyamine-ABC-transporter-ATP-binding-protein
MTEAAVEARSARKEYGAGEKKVRALNDVSVVINKGEFFTLLGPSGCGKTTLLRLIAGFESPTAGMILLGARDISTMAPYDRPVNTVFQSYALFPHLSVADNIGFGLTMQGTPKAQVQARVAEMLALVKLEAFAARKPQQLSGGQQQRVALARALAPAPEVLLLDEPLSALDLKLRKEMQLELKRLQTETGITFVFVTHDQEEALTMSDRIGVMRDGSILQIGGPREIYNKPVNRFVADFIGETNVLIGTVEQGGVRLPTGDVIAVDNLDAATQGTKVSLAVRPEQVRIGDGALQGRVAETVYFGTDTHCHLRMSDDTEVVARMQSPPSGDTGLQEGQTVAFDFVPGAVRVLED
>NZ_CP045410.1|WP_152497619.1|3312262_3313708_-|amidase
MDDYRAHDMTSLAGLVAKGEVTPDDLLDTALARMHAVNPALNAVVHDYSDTARRMIADGLPKGPLTGVPFLLKDMGAESTRHPASLGSRLLANTSYRMNSTIYDRLEASGLVTFGRTAAPEGGVGAATEAAVYGGPTRNPWDTSRTPGGSSGGSGAAVAAGIVPGAHGSDGGGSIRIPASNCGLVGFKPTRAMVPDGPYAGEGWAGMAIEGFLTRSVRDTALLLDIVCGPDLGAPYVAPPMPCTFMESLDRPNGPLRIALCDTTLTGEAIHPECQVAVQDAAALLHDMGHHVTQARPAADTTGMMHAWTKIVACGTASWVRAALAKQGRELRQGDIEGVARGAVEYAKTISGADYLDAVETVHAYGRQMAAFFVDHDILLTPTMAEPPAAIGRFAHDTEDYVAYRVGEGGIFAYSPYTAAFNATGQPAVSLPLCRGADGLPIGIHLAARFGADTALMSLCADIERARPWFDQIPALPGIDT
>NZ_CP045410.1|WP_152497620.1|3314001_3314397_-|metallopeptidase-family-protein
MPAPDTSLDWMEDVARRTVAGFPQAFAEAARAVAIHVADWPDREMLDSLDMTDPVELTGLYDGIPMTEKSVFDQPTGPDIVWLFRQPILAEWRDRGDVDLADLVAHVTVHEFAHHFGWSDDDIASIDRWWE
>NZ_CP045410.1|WP_152497621.1|3314436_3315348_-|MBL-fold-metallo-hydrolase
MSTLSRRTFLASATALSAAPALPAWATAPMLGAATPPFRRFKLGAFEVTTLLAGEATRPDPHTIFGLNVDEAEFTAVSEAAMIPTDQAQFFFTPTVVNTGSELVLFDTGLNAEGTTAALDAAGYSADMIDTVVITHMHGDHIGGLMEGDAPTFANADYVTGSAEFDHWSAAGDDNFEAKVRPLAEQFTMIGDGDAGFSGHTAMAAFGHTPGHMVHLIESEGESLMIAADFANHYVWSLAHPDWEVKFDMDKAAAAQTRKTILDMLAAEKMPFIGYHMPWPATGFVEKTDSGYAYVPSSYQLRL
>NZ_CP045410.1|WP_152497622.1|3315527_3316853_+|glutamate--tRNA-ligase
MTTTRFAPSPTGYIHIGNLRTALMNFLIARKNGGTFILRIDDTDPERSKQEYVDAIKQDLEWLGLTWDRVERQSERLDRYAQAAETLRGMGRFYEAFETPTELDLKRKKQLNMGKPPVYDRAALGLSDEQKDALRAERGDGVWRFKLDHERIEWDDGILGDISIDAASVSDPVLIRGDGQVLYTLASVVDDTEMGVTHVVRGSDHVTNTATQIQIIEALGGTVPSFAHHSLLTGPQGESLSKRLGTLSLRDLRAQGVEPMALLSLMARLGSADPVELRSEMAELIEGFDISRFGSAPTKFDANDLFPLTARVLQGRDFADVKAHILGLGVPEDQAERFWSVTRENITTLHDLEPWWVMFRDGAEPVIDDEDREFVAQALALLPEGPHDGDTWGQWTNAVKEETGRKGKGLFMPLRKALTGQNHGPDMSQVLPLLQVIRAKG
>NZ_CP045410.1|WP_172978902.1|3316934_3319040_-|nitrate--and-nitrite-sensing-domain-containing-protein
MRLRVVMFLVIAPLFAAVGYLTSVEVAQKRADAGQAETSRILAHESAIVGALVHELQKERGFSAGLIASRGANFRSDLARQRTDSDAAIAAFAAEVSALRRARPPEIASVNTRLDQLEDMRKQVDAFGLAVPDMAAFYTETITHLLELERPVAARTTRGETNALLEARTLLSAAKEAAGLERAMGATGLGSGFRPAVFNRYLRLNGAQEALLTEAAGTLEDPEWLARIRASDASATIRSARDRILAGTRTRNFDGLTAPEWFAISTAWIDLLRAEELKLFEAVRVKSAEIEATADTTLKRFAIFGSVLAVSVLAFAVFAFERMIARIKYLISVINKFTGGDFSVYIDGIDSKDELGQMASAIFHFKQETIEMRKGAEALKADQERIKAEQDQVVTALRDGLNRLSDGDLAQRFDNPFPQEYESLRHDFNTTVSRLNDALCKVVDATRSIRSGSGALERSSGDLSFKAEEQAQNVRNTADAVKEVTSSVRAASLGAGEVQQTTQAAKNAALESDPVVRQAVDAMEEISGSSEQIAQIIVLIEDIAFQTNLLALNAGVEAARAGDAGRGFAVVASEVRALAQRSTEAAMQIKTLIGNSSLQVKNGVELVNEAGTALKSILERVAQIDKLVADMAKATEEQASELENINTTVTRVDSVTQETATMAAEARTTCEDLNTYAGHLEQLVGQFSLTRPERDGLPSAA

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP045410_1	1.1|719517|26|NZ_CP045410|CRISPRCasFinder	719517-719542	26	MK305888	Streptomyces phage Austintatious, complete genome	23857-23882	3	0.885
NZ_CP045410_1	1.1|719517|26|NZ_CP045410|CRISPRCasFinder	719517-719542	26	NZ_CP045481	Amycolatopsis sp. YIM 10 plasmid pAmyYIM10, complete sequence	37746-37771	4	0.846
NZ_CP045410_1	1.1|719517|26|NZ_CP045410|CRISPRCasFinder	719517-719542	26	NZ_CP014169	Sphingomonas panacis strain DCY99 plasmid unnamed, complete sequence	5648-5673	4	0.846
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP038636	Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence	154749-154777	4	0.862
NZ_CP045410_1	1.1|719517|26|NZ_CP045410|CRISPRCasFinder	719517-719542	26	NZ_CP054841	Acidovorax sp. 16-35-5 plasmid unnamed1, complete sequence	393293-393318	5	0.808
NZ_CP045410_1	1.1|719517|26|NZ_CP045410|CRISPRCasFinder	719517-719542	26	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	199243-199268	5	0.808
NZ_CP045410_1	1.1|719517|26|NZ_CP045410|CRISPRCasFinder	719517-719542	26	NZ_CP038636	Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence	815961-815986	5	0.808
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP029830	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed1, complete sequence	325203-325231	5	0.828
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP054616	Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence	222255-222283	5	0.828
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	MT118296	Pseudomonas phage Epa19, complete genome	27060-27088	5	0.828
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	MT108731	Pseudomonas phage Epa43, complete genome	46240-46268	5	0.828
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	MT108725	Pseudomonas phage Epa5, complete genome	19152-19180	5	0.828
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP016083	Streptomyces sp. SAT1 plasmid unnamed3, complete sequence	257762-257790	5	0.828
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	MT770738	Rhizobium phage B1VFA, complete genome	97969-97997	6	0.793
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_LR134454	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 12, complete sequence	148158-148186	6	0.793
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP017322	Xanthomonas campestris pv. campestris str. CN18 plasmid unnamed3, complete sequence	17774-17802	6	0.793
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP017322	Xanthomonas campestris pv. campestris str. CN18 plasmid unnamed3, complete sequence	34950-34978	6	0.793
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	AP021851	Deinococcus grandis ATCC 43672 plasmid: pDEGR-2 DNA, complete genome	298477-298505	6	0.793
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP015231	Epibacterium mobile F1926 plasmid unnamed1, complete sequence	386903-386931	6	0.793
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP029831	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed7, complete sequence	151868-151896	6	0.793
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NC_016623	Azospirillum lipoferum 4B plasmid AZO_p3, complete sequence	256094-256122	6	0.793
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NC_013857	Azospirillum sp. B510 plasmid pAB510c, complete sequence	519409-519437	6	0.793
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP026526	Sinorhizobium meliloti strain AK21 plasmid pSymA, complete sequence	104333-104361	6	0.793
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP017309	Xanthomonas campestris pv. campestris str. CN03 plasmid unnamed, complete sequence	21691-21719	6	0.793
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NC_016585	Azospirillum lipoferum 4B plasmid AZO_p1, complete sequence	87112-87140	6	0.793
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	MH926061	Corynebacterium phage Troy, complete genome	20433-20461	6	0.793
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NC_048069	Corynebacterium phage SamW, complete genome	20433-20461	6	0.793
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NC_048790	Corynebacterium phage Lederberg, complete genome	20454-20482	6	0.793
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_LT703506	Mycobacterium chimaera strain Mycobacterium chimaera MC045 isolate Mycobacterium chimaera plasmid 2	274254-274282	6	0.793
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP013634	Rhizobium sp. N324 plasmid pRspN324d, complete sequence	417428-417456	6	0.793
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	811114-811142	6	0.793
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP020887	Xanthomonas citri pv. citri strain TX160149 plasmid unnamed2, complete sequence	53190-53218	6	0.793
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP029357	Azospirillum sp. CFH 70021 plasmid unnamed2	89609-89637	6	0.793
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP054617	Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence	463595-463623	6	0.793
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP017105	Rhizobium gallicum strain IE4872 plasmid pRgalIE4872d, complete sequence	149101-149129	6	0.793
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	MG945580	UNVERIFIED: Microviridae sp. isolate 3655-1711, complete genome	5392-5420	6	0.793
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NC_020062	Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence	185382-185410	7	0.759
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NC_003078	Sinorhizobium meliloti 1021 plasmid pSymB, complete sequence	144622-144650	7	0.759
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	LT599585	Pseudomonas veronii 1YdBTEX2 genome assembly, plasmid: PVE_plasmid	64273-64301	7	0.759
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP019586	Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymB, complete sequence	147359-147387	7	0.759
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP021799	Sinorhizobium meliloti strain USDA1106 plasmid psymB, complete sequence	212159-212187	7	0.759
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP021828	Sinorhizobium meliloti strain KH35c plasmid psymB, complete sequence	1394612-1394640	7	0.759
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP045120	Rubrobacter sp. SCSIO 52909 plasmid unnamed1, complete sequence	59846-59874	7	0.759
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP021823	Sinorhizobium meliloti strain KH46 plasmid psymB, complete sequence	1511145-1511173	7	0.759
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP021795	Sinorhizobium meliloti strain USDA1157 plasmid psymB, complete sequence	1060763-1060791	7	0.759
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP021806	Sinorhizobium meliloti strain T073 plasmid psymB, complete sequence	1099448-1099476	7	0.759
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP019484	Sinorhizobium meliloti strain B401 plasmid pSymB, complete sequence	354389-354417	7	0.759
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP019487	Sinorhizobium meliloti strain B399 plasmid pSym, complete sequence	141985-142013	7	0.759
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NC_020560	Sinorhizobium meliloti 2011 plasmid pSymB, complete sequence	144622-144650	7	0.759
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NC_019849	Sinorhizobium meliloti GR4 plasmid pRmeGR4d, complete sequence	1607329-1607357	7	0.759
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP028348	Novosphingobium sp. THN1 plasmid pTHN, complete sequence	453651-453679	7	0.759
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NC_017326	Sinorhizobium meliloti SM11 plasmid pSmeSM11d, complete sequence	1547534-1547562	7	0.759
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NC_017323	Sinorhizobium meliloti BL225C plasmid pSINMEB02, complete sequence	1152540-1152568	7	0.759
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP009146	Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence	1532464-1532492	7	0.759
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NC_018701	Sinorhizobium meliloti Rm41 plasmid pSYMB, complete sequence	1580037-1580065	7	0.759
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP021802	Sinorhizobium meliloti strain USDA1021 plasmid psymB, complete sequence	178935-178963	7	0.759
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP021820	Sinorhizobium meliloti strain M162 plasmid psymB, complete sequence	244057-244085	7	0.759
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP021831	Sinorhizobium meliloti strain HM006 plasmid psymB, complete sequence	163709-163737	7	0.759
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP021814	Sinorhizobium meliloti strain M270 plasmid psymB, complete sequence	1475630-1475658	7	0.759
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP021810	Sinorhizobium meliloti strain Rm41 plasmid psymB, complete sequence	703934-703962	7	0.759
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP026527	Sinorhizobium meliloti strain AK21 plasmid pSymB, complete sequence	1590609-1590637	7	0.759
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP049248	Rhizobium rhizoryzae strain DSM 29514 plasmid unnamed2, complete sequence	13704-13732	7	0.759
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_LR134461	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 19, complete sequence	7593-7621	8	0.724
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP013109	Sinorhizobium americanum strain CFNEI 73 plasmid B, complete sequence	97637-97665	8	0.724
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP032696	Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525b, complete sequence	219907-219935	8	0.724
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_CP013053	Sinorhizobium americanum CCGM7 plasmid B, complete sequence	95949-95977	8	0.724
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NC_019957	Mycobacterium sp. JS623 plasmid pMYCSM01, complete sequence	238420-238448	8	0.724
NZ_CP045410_3	3.1|3302963|29|NZ_CP045410|CRISPRCasFinder	3302963-3302991	29	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	1516350-1516378	8	0.724

1. spacer 1.1|719517|26|NZ_CP045410|CRISPRCasFinder matches to MK305888 (Streptomyces phage Austintatious, complete genome) position: , mismatch: 3, identity: 0.885

acgacgcccggaggcgcgccgcgagc	CRISPR spacer
tcggcgcccggaagcgcgccgcgagc	Protospacer
 **.********.*************

2. spacer 1.1|719517|26|NZ_CP045410|CRISPRCasFinder matches to NZ_CP045481 (Amycolatopsis sp. YIM 10 plasmid pAmyYIM10, complete sequence) position: , mismatch: 4, identity: 0.846

acgacgcccggaggcgcgccgcgagc	CRISPR spacer
acgacgcgcgggggcgcgccgcggtc	Protospacer
******* ***.***********. *

3. spacer 1.1|719517|26|NZ_CP045410|CRISPRCasFinder matches to NZ_CP014169 (Sphingomonas panacis strain DCY99 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.846

acgacgcccggaggcgcgccgcgagc	CRISPR spacer
tcgacgcctggtggcgcgccgcgaac	Protospacer
 *******.** ************.*

4. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP038636 (Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.862

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
atcatgatgatcttgccggtgccgcggcg	Protospacer
. ****.*****************.****

5. spacer 1.1|719517|26|NZ_CP045410|CRISPRCasFinder matches to NZ_CP054841 (Acidovorax sp. 16-35-5 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.808

acgacgcccggaggcgcgccgcgagc	CRISPR spacer
gttccgcccggcggcgcgccgcgagc	Protospacer
..  ******* **************

6. spacer 1.1|719517|26|NZ_CP045410|CRISPRCasFinder matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 5, identity: 0.808

acgacgcccggaggcgcgccgcgagc	CRISPR spacer
ctaacgccgtgaggcgcgccgcgagc	Protospacer
 ..*****  ****************

7. spacer 1.1|719517|26|NZ_CP045410|CRISPRCasFinder matches to NZ_CP038636 (Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.808

acgacgcccggaggcgcgccgcgagc	CRISPR spacer
gcggcgcccgcaggcgcgccgcgatg	Protospacer
.**.****** *************  

8. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP029830 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.828

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
gcaatggtggtcttgccggtgccggggct	Protospacer
*  ******.************** *** 

9. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP054616 (Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence) position: , mismatch: 5, identity: 0.828

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
gcaatggtggtcttgccggtgccggggct	Protospacer
*  ******.************** *** 

10. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to MT118296 (Pseudomonas phage Epa19, complete genome) position: , mismatch: 5, identity: 0.828

ggcatggtgatcttgccggtgccgtggcg-	CRISPR spacer
ggcatggtgaacttgccggtg-cgggctgc	Protospacer
********** ********** ** * .* 

11. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to MT108731 (Pseudomonas phage Epa43, complete genome) position: , mismatch: 5, identity: 0.828

ggcatggtgatcttgccggtgccgtggcg-	CRISPR spacer
ggcatggtgaacttgccggtg-cgggctgc	Protospacer
********** ********** ** * .* 

12. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to MT108725 (Pseudomonas phage Epa5, complete genome) position: , mismatch: 5, identity: 0.828

ggcatggtgatcttgccggtgccgtggcg-	CRISPR spacer
ggcatggtgaacttgccggtg-cgggctgc	Protospacer
********** ********** ** * .* 

13. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP016083 (Streptomyces sp. SAT1 plasmid unnamed3, complete sequence) position: , mismatch: 5, identity: 0.828

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
agcagggtgctcttgccggtgccgttggg	Protospacer
.*** **** *************** * *

14. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to MT770738 (Rhizobium phage B1VFA, complete genome) position: , mismatch: 6, identity: 0.793

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
aggatcgtggtcttgccggtgccgtggaa	Protospacer
.* ** ***.***************** .

15. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_LR134454 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 12, complete sequence) position: , mismatch: 6, identity: 0.793

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
agcatggtgctcttgccggcgccgttggc	Protospacer
.******** *********.***** *  

16. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP017322 (Xanthomonas campestris pv. campestris str. CN18 plasmid unnamed3, complete sequence) position: , mismatch: 6, identity: 0.793

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
agcatcgtggtcttgccggtgccggcgag	Protospacer
.**** ***.**************  * *

17. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP017322 (Xanthomonas campestris pv. campestris str. CN18 plasmid unnamed3, complete sequence) position: , mismatch: 6, identity: 0.793

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
agcatcgtggtcttgccggtgccgcgagg	Protospacer
.**** ***.**************.*. *

18. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to AP021851 (Deinococcus grandis ATCC 43672 plasmid: pDEGR-2 DNA, complete genome) position: , mismatch: 6, identity: 0.793

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
agcgtggtggtcttgccggtgccgggtcc	Protospacer
.**.*****.************** * * 

19. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP015231 (Epibacterium mobile F1926 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.793

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
tgaatggtgatcgtgctggtgccgtgccc	Protospacer
 * ********* ***.********* * 

20. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP029831 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed7, complete sequence) position: , mismatch: 6, identity: 0.793

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
gacatggtgctcttgccggcgccgttcgg	Protospacer
*.******* *********.*****   *

21. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NC_016623 (Azospirillum lipoferum 4B plasmid AZO_p3, complete sequence) position: , mismatch: 6, identity: 0.793

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
gacatggtgctcttgccggcgccgttcgg	Protospacer
*.******* *********.*****   *

22. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NC_013857 (Azospirillum sp. B510 plasmid pAB510c, complete sequence) position: , mismatch: 6, identity: 0.793

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
gacatggtgctcttgccggcgccgttcgg	Protospacer
*.******* *********.*****   *

23. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP026526 (Sinorhizobium meliloti strain AK21 plasmid pSymA, complete sequence) position: , mismatch: 6, identity: 0.793

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
agcatggtgctcttgccggagccggaacg	Protospacer
.******** ********* **** ..**

24. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP017309 (Xanthomonas campestris pv. campestris str. CN03 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
agcatcgtggtcttgccggtgccggcgag	Protospacer
.**** ***.**************  * *

25. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NC_016585 (Azospirillum lipoferum 4B plasmid AZO_p1, complete sequence) position: , mismatch: 6, identity: 0.793

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
atcatggtggtcttgccggcgccgttggg	Protospacer
. *******.*********.***** * *

26. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to MH926061 (Corynebacterium phage Troy, complete genome) position: , mismatch: 6, identity: 0.793

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
gccatggtgattttgccggtggcgtcgac	Protospacer
* *********.********* *** *  

27. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NC_048069 (Corynebacterium phage SamW, complete genome) position: , mismatch: 6, identity: 0.793

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
gccatggtgattttgccggtggcgtcgac	Protospacer
* *********.********* *** *  

28. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NC_048790 (Corynebacterium phage Lederberg, complete genome) position: , mismatch: 6, identity: 0.793

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
gccatggtgattttgccggtggcgtcgac	Protospacer
* *********.********* *** *  

29. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_LT703506 (Mycobacterium chimaera strain Mycobacterium chimaera MC045 isolate Mycobacterium chimaera plasmid 2) position: , mismatch: 6, identity: 0.793

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
gcgatggtggtcttgccggtgccgggcgg	Protospacer
*  ******.************** *  *

30. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP013634 (Rhizobium sp. N324 plasmid pRspN324d, complete sequence) position: , mismatch: 6, identity: 0.793

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
agcatggtcgtcttgccggtgccggtgcc	Protospacer
.******* .**************  ** 

31. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 6, identity: 0.793

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
gacagggtgatcgtgccggtgccgttgac	Protospacer
*.** ******* ************ *  

32. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP020887 (Xanthomonas citri pv. citri strain TX160149 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.793

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
agcatcgtggtcttgccggtgccggcgag	Protospacer
.**** ***.**************  * *

33. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP029357 (Azospirillum sp. CFH 70021 plasmid unnamed2) position: , mismatch: 6, identity: 0.793

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
agcatggtgatctcgacggtgccgacgcc	Protospacer
.************.* ********  ** 

34. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP054617 (Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence) position: , mismatch: 6, identity: 0.793

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
cggatggcgatcttgccggtgccggagag	Protospacer
 * ****.**************** .* *

35. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP017105 (Rhizobium gallicum strain IE4872 plasmid pRgalIE4872d, complete sequence) position: , mismatch: 6, identity: 0.793

--ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
tcgcctt--tgatcttgccggtgccgttgcc	Protospacer
  * * *  ****************** ** 

36. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to MG945580 (UNVERIFIED: Microviridae sp. isolate 3655-1711, complete genome) position: , mismatch: 6, identity: 0.793

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
agcaaggtgagcttgccggtgccgaagct	Protospacer
.*** ***** ************* .** 

37. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NC_020062 (Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence) position: , mismatch: 7, identity: 0.759

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
attgtggcgatcttgccggtgccgtggat	Protospacer
. ..***.*******************  

38. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NC_003078 (Sinorhizobium meliloti 1021 plasmid pSymB, complete sequence) position: , mismatch: 7, identity: 0.759

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
cacatggtgagcttgccgttgccgtccca	Protospacer
 .******** ******* ******  *.

39. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to LT599585 (Pseudomonas veronii 1YdBTEX2 genome assembly, plasmid: PVE_plasmid) position: , mismatch: 7, identity: 0.759

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
agcacggtggtcttgccggtgccggacgg	Protospacer
.***.****.************** .  *

40. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP019586 (Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymB, complete sequence) position: , mismatch: 7, identity: 0.759

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
cacatggtgagcttgccgttgccgtccca	Protospacer
 .******** ******* ******  *.

41. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP021799 (Sinorhizobium meliloti strain USDA1106 plasmid psymB, complete sequence) position: , mismatch: 7, identity: 0.759

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
cacatggtgagcttgccgttgccgtccca	Protospacer
 .******** ******* ******  *.

42. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP021828 (Sinorhizobium meliloti strain KH35c plasmid psymB, complete sequence) position: , mismatch: 7, identity: 0.759

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
cacatggtgagcttgccgttgccgtccca	Protospacer
 .******** ******* ******  *.

43. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP045120 (Rubrobacter sp. SCSIO 52909 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.759

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
gattcggtgatcttgccggggccgtcgcc	Protospacer
*.. .************** ***** ** 

44. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP021823 (Sinorhizobium meliloti strain KH46 plasmid psymB, complete sequence) position: , mismatch: 7, identity: 0.759

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
cacatggtgagcttgccgttgccgtccca	Protospacer
 .******** ******* ******  *.

45. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP021795 (Sinorhizobium meliloti strain USDA1157 plasmid psymB, complete sequence) position: , mismatch: 7, identity: 0.759

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
cacatggtgagcttgccgttgccgtccca	Protospacer
 .******** ******* ******  *.

46. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP021806 (Sinorhizobium meliloti strain T073 plasmid psymB, complete sequence) position: , mismatch: 7, identity: 0.759

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
cacatggtgagcttgccgttgccgtccca	Protospacer
 .******** ******* ******  *.

47. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP019484 (Sinorhizobium meliloti strain B401 plasmid pSymB, complete sequence) position: , mismatch: 7, identity: 0.759

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
cacatggtgagcttgccgttgccgtccca	Protospacer
 .******** ******* ******  *.

48. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP019487 (Sinorhizobium meliloti strain B399 plasmid pSym, complete sequence) position: , mismatch: 7, identity: 0.759

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
cacatggtgagcttgccgttgccgtccca	Protospacer
 .******** ******* ******  *.

49. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NC_020560 (Sinorhizobium meliloti 2011 plasmid pSymB, complete sequence) position: , mismatch: 7, identity: 0.759

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
cacatggtgagcttgccgttgccgtccca	Protospacer
 .******** ******* ******  *.

50. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NC_019849 (Sinorhizobium meliloti GR4 plasmid pRmeGR4d, complete sequence) position: , mismatch: 7, identity: 0.759

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
cacatggtgagcttgccgttgccgtccca	Protospacer
 .******** ******* ******  *.

51. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP028348 (Novosphingobium sp. THN1 plasmid pTHN, complete sequence) position: , mismatch: 7, identity: 0.759

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
tcgttgccgatcttgccgatgccgtggcg	Protospacer
    ** .**********.**********

52. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NC_017326 (Sinorhizobium meliloti SM11 plasmid pSmeSM11d, complete sequence) position: , mismatch: 7, identity: 0.759

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
cacatggtgagcttgccgttgccgtccca	Protospacer
 .******** ******* ******  *.

53. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NC_017323 (Sinorhizobium meliloti BL225C plasmid pSINMEB02, complete sequence) position: , mismatch: 7, identity: 0.759

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
cacatggtgagcttgccgttgccgtccca	Protospacer
 .******** ******* ******  *.

54. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP009146 (Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence) position: , mismatch: 7, identity: 0.759

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
cacatggtgagcttgccgttgccgtccca	Protospacer
 .******** ******* ******  *.

55. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NC_018701 (Sinorhizobium meliloti Rm41 plasmid pSYMB, complete sequence) position: , mismatch: 7, identity: 0.759

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
cacatggtgagcttgccgttgccgtccca	Protospacer
 .******** ******* ******  *.

56. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP021802 (Sinorhizobium meliloti strain USDA1021 plasmid psymB, complete sequence) position: , mismatch: 7, identity: 0.759

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
cacatggtgagcttgccgttgccgtccca	Protospacer
 .******** ******* ******  *.

57. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP021820 (Sinorhizobium meliloti strain M162 plasmid psymB, complete sequence) position: , mismatch: 7, identity: 0.759

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
cacatggtgagcttgccgttgccgtccca	Protospacer
 .******** ******* ******  *.

58. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP021831 (Sinorhizobium meliloti strain HM006 plasmid psymB, complete sequence) position: , mismatch: 7, identity: 0.759

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
cacatggtgagcttgccgttgccgtccca	Protospacer
 .******** ******* ******  *.

59. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP021814 (Sinorhizobium meliloti strain M270 plasmid psymB, complete sequence) position: , mismatch: 7, identity: 0.759

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
cacatggtgagcttgccgttgccgtccca	Protospacer
 .******** ******* ******  *.

60. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP021810 (Sinorhizobium meliloti strain Rm41 plasmid psymB, complete sequence) position: , mismatch: 7, identity: 0.759

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
cacatggtgagcttgccgttgccgtccca	Protospacer
 .******** ******* ******  *.

61. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP026527 (Sinorhizobium meliloti strain AK21 plasmid pSymB, complete sequence) position: , mismatch: 7, identity: 0.759

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
cacatggtgagcttgccgttgccgtccca	Protospacer
 .******** ******* ******  *.

62. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP049248 (Rhizobium rhizoryzae strain DSM 29514 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.759

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
aacatggtggtcttgccggcgccgttcgg	Protospacer
..*******.*********.*****   *

63. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_LR134461 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 19, complete sequence) position: , mismatch: 8, identity: 0.724

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
gtggtggtggtcttgccggtgccgttcac	Protospacer
*  .*****.***************    

64. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP013109 (Sinorhizobium americanum strain CFNEI 73 plasmid B, complete sequence) position: , mismatch: 8, identity: 0.724

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
tcggccgcgatcttgccggttccgtggcg	Protospacer
   .. *.************ ********

65. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP032696 (Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525b, complete sequence) position: , mismatch: 8, identity: 0.724

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
ttggccgtgaccttgccggttccgtggcg	Protospacer
   .. ****.********* ********

66. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_CP013053 (Sinorhizobium americanum CCGM7 plasmid B, complete sequence) position: , mismatch: 8, identity: 0.724

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
tcggccgcgatcttgccggttccgtggcg	Protospacer
   .. *.************ ********

67. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NC_019957 (Mycobacterium sp. JS623 plasmid pMYCSM01, complete sequence) position: , mismatch: 8, identity: 0.724

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
gcgatggtggtcttgccggtgccgccctt	Protospacer
*  ******.**************.  . 

68. spacer 3.1|3302963|29|NZ_CP045410|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 8, identity: 0.724

ggcatggtgatcttgccggtgccgtggcg	CRISPR spacer
acggtggtggtcttgccggtgccgttgac	Protospacer
.  .*****.*************** *  

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	371527 : 401188	29	Acidithiobacillus_phage(22.22%)	transposase,terminase,integrase	attL 361778:361808|attR 407464:407494
DBSCAN-SWA_2	1970517 : 1983370	14	Enterobacteria_phage(33.33%)	NA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP045410|371527:401188|DBSCAN-SWA
CTCAGAACGCGGGCTGCCGATATTCCTGTTTCTTCGTGAGCATCGCCCAGATGATCCTGGCTGCCTTGTTCGCCATCGCGGTTGTGGCCAGCCGGAACGGCTTGTCCGCGATAGTCTTGGCGGTCCATAGGTCGACTTTCTCGGGTGAGCGCTTCGCCATGACGGCGCGCGATGTCATGCTGACGACCAGCAGCTTTCGAATGTAGCGATCGCCTTTCTTAGTGATCTTGCCGAGACGCTCCTTACCCCCACTCGATTTGTTGAGCGGGGTTAAGCCCAACCACGCCGCCAGGTCACGTCCTGTTCGGAACTGATGCGCGTCACCGATCGTGGCGACAATCGCCGAGGCGGTGATCGGCCCGATCCCAGGCATGCGCATCAACCTACGCGCATCCGCATTGAGTAGCGCGTGTTGTTCGATCATCTTGGAATAGCCGTCAATGCGCTCGTTCAGGCCGATGAACTGATAACACTGGATGCCGAGCATGCTGTTGGCGATCTCCGGCATGTCCGGGTGATCACCGTTAAGGTGGCGCTTTGCAAAGGCCGTTACCGCTTCGATCCCGATGGGCAAGATATGCCCAAACTCGCGCAGAAGGCTACGGATCATATTGGCCATCTGGGTGCGTTGCCGAACAGCCAGGTCTCGCGTTCGATGAATAGAGAGAATGGCTTGCTGTTCCTCCGTTTTGATCTCGACAAAGCGCATGGTCGGGCGCCGAACTGCTTCGCAGATCGCTTCCGCATCAACAGCGTCGTTCTTCCCGCGCTTCACATACGGTTTGACGTAGCCAGCGGGCATGAGCTTCACATCATGGCCAAGCTTACGCAGCTGCCGGCCCCAGTGATGCGAAGAACCACACGCTTCCATGCCGACCGTGCAAGCCGCCAGCGTCTCGAAGAACGACAACAGCTTGGCGCGCTTGATTGCCTTGTTGAAGATAACCCGGCCATTCTCTGAAATGCCGTGCACTTGAAATACGTCCTTGGCCAAATCGAGGCCCACAGTCTTTACTGTCATTGGGTGGCTCCTTTGCTCGCAGTCTATGACAACTGCACTTTGGCACGTTCGATGCCGGTGGAGCAGGAGCCATCCACCTCATCCGCTTTGGGCCGGTAGCTAACCAGTTCGACTACAATACGGTTTTGAGGGTACCCGTGCTTTGCTGCAAGCTTTAATTCTTGACCTGTCTGCGATGGAGCTTCGGCAACGGCCTATGCCATCTAGAAATGAGCTACATGTCCGTCGCCAGAGTACTTCGGAGTTCTGAGGCGTTTTGGTAACGGAGGCTCAACAACGACTAGCTAAGCGTCTTCGGGTTCACCTATATCTATCGCGTAAAGGTCTGCCTGAGTGCCGCAACATGCCGGAGAGAGCCGCACTGCTACAGGCTTTGAAGCAACCCTTGCGATGGAGTGCCTGTCACAGGTAGGCCGCGGCTTTCTTGGTAGGCGCGGATTGCAGCCTCCGTGTCGCGACCTATCACACCATCCGCGCCCTGGGTATCGAAACCACGCGCAGTCAGACGCTTCTGCAGGCGCACTCGATCAGCCTTGGTTAGGCCGTTGGCATCGGGTGGGAACGCCGTCCGCAAAGGACCACCGCCGCGAATACGGTCGGACAAATGCCCGACGCCGATCGCATAGGCGTCCGAGTTGTTATAGCGCTTGATCACACTGAAATTGCGCGTGGTGGCGAAGCGTGGGCCGCCGGGCTGTGGCTGAAGTGACCCATTGCTTGTCTCAGACCCCCAGCGAACACCGCGCTGCCAACCATTGCGTTGCAGATAAGCGGCCGCAGAGGCCAAAGCATCGCTGGGGTCATCAGACCAGATGTCGCGCCGTCCATCGCCAGTGTAATCAACAGCAAATTGCAGGTAAGATGTTGGGATGAACTGGGTGTGGCCCATCGCCCCTGCCCAGCTACCCGTCATGCGGCTGGCCGGAATATCGCCATTCTGAACAATGCGCAGTGCCGCGATTAGCTGCTGTTCGAAGAACTGCCCGCGTCGACCATCAAATGCCAAGGTCGAAGTGGCCGATATCACAGGCACCTCCCCCCGCCTTTCACCGTAGAAGCTTTCCAAGCCCCAGATAGCGGCGATGATATAGGCATCCACACCATAGCGATCTTCAAGCGCCATTAGCGTTCCGCGATGGCGAGCAAAGGCGGCCCGTCCCTTTTGAACCCGCTCCTCCGAGGCGGCAATCGCGAGGTAGTCCTCCAAGCTGCGTTTGAACTCGGTCTGATTACGGTCCCGCGTAACAACCCCCGGTAGATAGCCGGTATTACGGAAAGCCGAGGCGAGAGTGCTTTGTGAAATGCCTTTCGTCGCTGCGCGCTCGCGGAAGGAAGCAACCCAAGCGTCGTAATTTACATTTGGTACGGGCCTGAGATCGGCCGGAAGACCACTCGGAATGGTGGATCTGACCGTGCCTGGCCCTGAACTGCCACAGGCGGATACGCCCAAAGCAATCGCCCCAAGCCCAAAGCTGCGTCTTGTTATTTGTATCCGTCTGCTCATCACTTGATGCGTTTTCCCTACTAAGGAGGCCCTCCGGGACTAAGACACCGAGTGGCCGTTCTTGATGCCTAATGCAGGATTGAGCCTCGGTCCATCTGGATATTCAAACTAGCTGTGGGAGCGGCACCGGTCCATGATGTTCGTCCAGTTTGTCACGCATAGTGCGAGGTCGCAATCATCGTACTTTGCTTTCGCAGTAAGCGGCAGGTTTTATGGGCCGCGAGGCAGTATCTAGCGGACCTTATGACCGGTAGTAATGTAGCGGGAGCGAGTATGTGCCAGCTTTCGGACCAACGTCAGCTGTGCGGACAAAGCTGACGTTCCTTCTGCGCCGAAAAATGACTAGTATTGGGAAAATGAATTGAGGGCAGCGCCTAAGCTGAGCTGAGCATGATAGAACTGCATGGCTGGTCTACAATCAGAGAAGCGTTTCGCGAACAAGATGAATCTGATGAAGTGTTGTCTTCTGCAATTTCGCAAATTGAGCAGGCTATCAGTAAGTTGAGCGATTTCAATCTGGCTGCAAAGCTAATGTCGCAGAACGGGATTAATAGCCTGCTGATAAATGGAAACTTTAATCATCGAGACATGGTGACCTGCTCCCCTTGGAGTCCGCATTTATCAGTTAGCTCTGTTCAGGGTTTGGTCCTCTTCTGACCGTTGGTGATACTCCCGCGGCGTGAGCCCGTCGAGGCTCGAATGCGGGCGGTGTTGATTGTAGTCTTCGCGCCATGCCGCAATCATGCGGCAGGCATGGCGCAGAGACGGGAACAGATGCTCGTTAAGGCATTCCTCGCGCCTCCGGCCGTTGAAGCTCTCGACCAAGCCATTCTGCATCGGCTTGCCGGGAGCAATGTAATGCCAGTCGACCTTGCGGTTCTCCTGCCATTTCAGCATCGCATTCGAGGTCAGCTCGGTGCCGTTGTCGCTGACCACCATGCAAGGGTAGCCGCGCAGTTCTGCGATACGGTCCAGCTCGCGGGCGACACGTGCACCGCCGATTGATGTGTCGACGACAGCTGCCAGGCATTCCCGGGTGAAGTCGTCAATGACGTTCAGCACCCGGAACCTGCGACCGTCCTCAAGCGCGTCGGACATGAAGTCGAGTGACCACCGCTGGTTCGGTCCCTGCGGTATCGCCATCGGCGTTCTGGTGCCCACCGCACGCTTGCGACCGCCCCGTTTACGAACGGTTAACCCTTCTTCGCGGTAGACACGATAGAGCTTCTTCCAATTGAGCTCCCAGCCTTCGCGCCTTAGCAGAATATGCAGCCGACGATACCCGAACCGCCGCCGTTCAGAAGCCAGTTCCTTCATCCGAGCGCGCAGCTCTGTGTCCTGCGGTCGCTTCGTCTTGCGCCGATACACACGCGGTTCGATCCCGGCCAGCGCACAGGCGCGTCGCTGATTGTAGCCCTTGGTCTTCATAGCCCAGTCCACGGCATTCCTCCTCGAACCGGGCTTCAGAAGTTTTTTCCGAGCATCTCTTTCAGGGTGGCAACGTCGAGCATCTGCTCCGCCAGCATCTTCTTCAGCTTCGCGTTCTCAGCCTCCAATGCCTTCAGACGCCGGGCGTCAGACACCTCCATGCCGCCATACCTCGACCGCCACTTGTAGAACGTGGCGTCGCTGATCCCGTGCTTGCGACACAGCTCCTTCGCACCGAAACCAGCCTGGTGCTCCTTCAGGATGCCTATGATCTGCTCTTCGCTGAAACGGCTTCTCTTCATCATCTGTCTCCTTCGTTGGAGAACAGGCTAACCTTAAATCGAGGACTTTTCAGAGGAGCAGGTCAGGTGGCTCCTTTGCTCGCAGTCTATGACAACTGCACTTTGGCACGTTCGATGCCGGTGGAGCAGGAGCCATCCACCTCATCCGCAATGGGCCGGTAGCTGACTGGTTTAGCGACAATACGGCTTCGAGGGAATCGCCCGAGAAGCTTCGGTTTCGAATTTTCGATACCTACCGCCTGAGTACCGAGGGCAGTCTCTGGCATGTCCGGCAGCTATTACAGCAGCCCCCAGATCCAAACCATCCTTGTCCCAGCAGACGCCTACCCAGCGGTCATAGGTCTTCTCACCGCTGAACTCGCAAGTGATCAAAGCATTGCCGTAGGCGTTCTGCATCCAGCGCTTCCCGGCCCGTCCGCCCCGTTCGTCCAATTCGGGAGCATCAACCCCATTGAGCCTCACGGCAATGCGTCCGCGACTTGTTGCAATCTCGATAGTGTCTGCGTCGCGTACGTGAACAAGTTTACCGCTGAGGGTTGTTGCCAGAGCGTGCGAAGGAGCGCCAAATGCGCAGACTGTTGTGAGTAGCACGGCGGAGAATTTGGATTTCAGCATTGAGATATCCGTTACATTTTGAAGACTTCTGCAGACCGGGGCCTAAACAGACATGCTGGCAACTTACAGGCAGTCTTGTGGTTAATTCTGACTTTCACTTGTTTGCTCCGTGCCCATGAGCAGCCGTTCTTTCGCTGTTCCCCACTTTGCGAAGTAGTCCCTGGCATTTTCACTGAGCCCGTATTTTGCAGCGTAGGCCGCAAGGATCCGCTCTGCTTCTTCCAGTCGAGCTTTGGTCATCTCTAGGTCTCCTGTGCAGGGAGTGTCGCATCCGAAGGTTAACAAACCATTATCGCGGCGCGCGTGTATCCTTCCCCAATCGCCAATTGCTTGTGGAGGACTGGATAATGGCACGTGAGTTTGATCGGGAAACGGAGCGCATGGCAACAGTTGTGAAGCTGGCCGACATACCCAAGAACCACCGAGAAGAACTAATACGAGAATATCGAGAGCGCTCTGAGGCTGCCTTCGCACCGACCACTCTGCGCAACTTTCGCCAGATCACTCACAACTTCCAAGTATGGTGTCGCGAGCATGGCTTCGACCCGCATCCGCCGATCGATCCGAGAGCTGTGGCTGAGTACGTGGATTCCCTCGGCGGCAAAGTTCGGTGCACGACCATTGAAACCAGGCTCTGGGCCATTTCAGAAATGCATCGAGCGGCGTTCCAACCGACGCCGTGTCGCCACAGGCTTGTTGAACTCGCCTTGAAGGGCGTGAAGCGAAAGTACGGTGCGTGGGTGCGTCAGGCTCCGCCCCTGTGCAAGGCAGAGGTCTATAAGGCCATCGACAAACTGGGAAGTTCCAGACTCGAAACCCGCGACAAAGCCGTACTCTGGATTGCTACGGATAGTTGGTGTCGTGCGTCGGAAATCATCGCTCTCAGGGTTCGCGACTTGATGCGGCAAGACGATGGATCGAGTTTGCTGTTCATCGCGCGTTCCAAGACCGATCAGTTCGGGCACGGTGCATACGCCTATCTTTCCGAGGCGGGTACTCAGGCAGTCCTAGAGTGGATCGAGATGGCGAAACTCAAGAACGATGACCCTCTGGTCACCAAGCACCAAGCAAACGCTCAGGTCGGCCCGATGGACGCAGCCACGATTTCCCGGATCATCAAGCGCTGCACAGGACGAACTGACGTCTCTGCTCACAGCATGAGGGTTGGCGGGGTACATGATGCCTTCCGCATTGGCTGCGACCTGTCCTCGATCATGGTGGCCGGGCGGTGGAGTTCGCCTGAGATGCCCGCGCGGTATGGCAGAAGAATACTGGCCAGCAATTCTGCCGCCGCTCGGGTTTCCCAGGTCCTCGGTGCAAAACGGCAGCCGAAAGCTTAGTTCGGGCGCTCCGCATCCTTGAGGATCTTAACAACCTCGGGTTCGGTCATGGCAAAATTCGAACGTGGCCACGAGTCCATCGGGTCTATGCGTCCATAGGCTCGCCAGTCGGTCCCTTGGAGTGAGCGCGACAGGGCTTCAAGCTCGGTCTTTTGAAGATGAGCGCGCTCAACAAAATGCCGGTCAAGCGCGGCGAAATGCGTTCGCACCTGAACTTCCCGAATTTGCGGGGCCAAATGACCATAGGTCCGGCTTACCGTGTCAGTGTTGGCGTGACCGAGTTGCTGAGCAACGACAATCAGCGGCGTCCCCGCCTGGACGAGTTGACTCGCATACGTATGTCGTAATCCATGGAAAACGAAAGCAGTTGGGAGCTCGGCTTGAATGACGGCTTCTCGAAAGAGATGCTTGTGGCCGTTTTGCCATGACTGCCCCGACTGTCGCCGGAACACCAAGTCATCGGGCAACCGACCAGCACACAGGTCAAGAAAGAATGCCATACCTTCATCGGGCAGGAAGACATAGCGTGGCTTCCTAGATTTCAGAGGCTCGACATAGAGGCCGAACACGTGCGCGGCCACGTCTCTGACCCGAAGCTTGGCAAGTTCAGTGATGCGGCACCCCGTGTAGAGAGCGCCTTGAACAATTTCCCGAAGGTCCGGACGGCAACAATCCAGAAGCCTGCTGCATTCTTCTCGCGTGAGAAAAATGGTTCTCGGGGTGTCCGCCAATGGTACCCTGCGGATACACCGCCATGAACGTTCAGAGTCCGTTTCGCCGTTTTCCCAAGCCAGTTGCACGGCCAGGCGCAGGACACCGATCAAGCCGTTCAGCGTCTTCTTGCGCTTTCGAAGGTCGTCTGGGTCGAGCTCAATCAAAGGAAGGCGCTCAATAGCTTTCTGTTTGCCGCGTTTAGGTGGCGTTTCGAGAACATCGAGAGAGAACTGCACGATGTGCCGACCCGTCAATTCATCGAGCGGCATATGCCCAAGCCTTGGAAGAATGTGGTGGTTGATCCGGCTCACCATCGAGTCGAAGTGGCTCTTGGTTGCGGAGATTCTTTTCCACTCCACGTAGTCCCGCATCGCATGGCCCACTGTGAAGACATTCCCCCAAGGGCAGTAATTGAGGTCCTGCTTTGACCCTATCGGAAATGGATCAGCTGCCTGCTTCGCGATTTTAGGTTGACTGAACCAACGTCTGGCAGCCTCCAAGGCTTCGTCGTAGTTGTCTGTCTGAGCTTCCCACGGGATCAGGCGCTTTTGGTAGTATCCAAGCGATTTGTTACGGATACGAGCGACCCAATATCCTGAGACGGGTGTTTTCTTCTGTAGGCCGATATGGCGGCAATATTCGAGAATCTGCCAGTGCGGCGCTTCTCGCGACTTCAAGGTTTCTATTGTCTGGCTATTGCTAAGGTCTGGCATGCGGGAGGTCTCCGAAGGTACTCGGGGAATAAGCCTCACATGCAAACTGTTGGCAGTGGATGTGAATTGTTGGAGCGGGCAACAGTTCTGACAGAGATTTTTTGGCTTCTGTCCCCATTATTCCACAATTGGATAACGCTTTGCGTTGAGTTTGGTAACGGAAATGTTGAGCCGACACTTTCAAGAAAAACCGTTATTGGCTTCAATAAAATTTCGTACTTGGACGCAAAGGTCGTCGCCCATGTTGCGCTATGAAAGGTGTGCGCAAAGTCCCTTAATGGATGGCATTCCGCTACTCGGATTTTGGAGCCTCGTTTCACGTTTGCCCCCTCGAAACGGGTTGTTTCGCAGACAACCCTGAACGGCCAATTTTAGACACATTCGCGCCGCATTTTGCGCACGGACAAATCGCAAAGCTGACTATCAGTAACGAGTGGTTAAAACTGATTTCTATGATGAAAGCGGCGACCGTCCGTGACTGGCGGTTGCCGCATTTTTCATTTTGCCAATAGAGCCAGATCCCGGTGGTTCTTGGCGATCTCGACGCAAACGCGAATGGCCCAGACGTGCTTGGCAGCAAGGGTCGTTTCTGGCGACGATACGACCTTTGTTCCAAGCGGGTCTGCAGGCTCGAATTGCAGGTAAGTTCGCAATTGTCATGGCGATTGCTCCGATCGGTCACTCCCCGCCTCAACGCCAACCCGACGTTTGCAATAGAGTATACCACAATCGGATGAATCCGCAGTTAGGAGCGTGGTAAAAAGAGTAACCTTATATACTGCCGCAGCAACATGACCTGCCCAGCCGTCATTTTAGGCTCACCCAGCGACTTGGCAATCACGATCCCACCTTCGACCACCGTACTGACGAAATCGGCAAGCGCATTCAGGTCGACTTCTTCTTGGGGCGGATACACCTTCGCGATCTCGTCGAACATCTCTCGGAAGCGCCGCCGCCAACCCAATACGGCCCGCCGGTTGGCATCGCGGACCGCCTGGTTGAACAGCCGCTCCTGATAAGCTGCCGTGGCGACGATGCATCCAGGGTGCCCGGCCTCCATGTCCTCCAACAATTCGGCAAGAAGCTTGAGCCCGATCAGAGCTCGATGGAGAGGGTCATCCGATAGCTCTGCCGCCCGAGCGAAGAGGTCATCGAATATCTGATCCTCAAATATGACATGGCGTTCGATCAGGGCCAGAGCCAAAGCGTTTTTGTCGGCAAAATGATAGAAGAAACCGCCGCGCGTGATATCCGCCGCTGCAACGATCTCGTCTATAGAGGTTGCATCGAAGCCTTTTGCCAGAATCGAATCCTGCGCGATGTCGAGCAGCTTTTCCCGGTGGCTCGGTCTTGGCATGTCAAACTGGACCTTCGGTAAGGTTTCAACCGGGGTAGACTAGGTGCGGATCCGCTGCCCAATCATCAATACATTGAAATAAATCGAAAATTCTCACAGAGACGAAAGTGTACCATGCGTCTGCTGTTCAAAAAAGAGCTGCTCGATCAAAACGAGCGAACCAAGAATTTAGGAGCACAGCAATGGCACATGCAGCAAGTTTCAACAATTTCATTACGTCTAACCAGGCATGGGTGGCAGATGGCGGGCTTGAGACCGACCTGATCTTTTCCGACGGCCTCGACCTTCCGCACTTCGCCTCGTTCCATGTCTTCGACACGGAAGAAGGTTGCGCGACCCTGGCACGGTACTATGACCGCTATATCGAGGTTGCACGCAGCGCGGGCACCGGCTTTGTGCTGGATACGGCGACCTGGCGATCAGGCGCGTTCTGGCCCGAGACCGTGGGCCGGTCGCTCGCCGATCTTGAGGCCGCGACTCGCGAGGCGGTGCGATTTGCGCGCGACACCCGTGGGCGGCACGCAGATGTGCCGATGGTTCTGAATGGCGCCATCGGTCCGGCGGGCGACGGCTATGCGCCTGACCGGCTCTACAATCAAGATGCGGCCGAGGCACTTCACGCACATCAGGTTCGCTGGATGGCGGAGGAAGGGATCGAGATGATAACCGCGGTGACGATGACACATCCCGACGAGGCGATTGGGCTCGTCCGCGCAGCAAGTGATTGGGATCTGCCCGTGGTTGTCAGCTTTACGACCGAGACCGATGGCCACCTGCCGACCGGCGAGACCATCGAGTGGGCAATCACCAAGACGGATGTTGCCACTGGCGGTGCTCCGGTCTTCTACATGATCAACTGCGCCCATCCCGATCATTTTGCGGCGGAGCTGGCTGGCGATTGGACATCACGCATCGGTGGAATCCGCGCTAATGCCAGTCGCATGAGTCACGAAGAACTGGATGAGGCCCAGGAACTGGATGCCGGCGACCCCGACGAGTTCGGCAAGCTTTACGGTGATCTCTTTCAGACCTTGCCAAGGCTCAGAGTCATCGGGGGATGCTGCGGAACTGACAAGCGCCACATCGGTTGTGCGGCGCATCATGTCATCAACCGGTTCGGCCAAGGTTGGAATGAAGAGGTCATCGCATCGTAGTTTGCAGACAGGCTGTTTCATAAAGGTCAGGCGAAAGCCCGACCCGTTCCACCGCCTGATCGGGAAATTGGCAGAGTAATCGTTCACGGAAGCAATCCATCAGCTGGCTTTTTGGCGGTATTCTGACTTGCCGCAGCAGGACTTAACCCCAACCTAAGATGAAGTCATCGAACGGAAACTTTATCTCGACAGGAGCGCCTTGATGCGCGGCACATCAAACGATTGTTTCGCGCCTAAGGGAGCCTTCGGCCACACCGCTTGCTTGCTGGTTTATCGATAGGGCTCGTTTTTTTGTTCTGCTGCGGCAGAGATTTCGGAGACTGAGATGATCACACTGGAACCCCCATTCAGGTTTGCCACACCCTCGGACTCGGCAGAGCTCGCGGATCTCGTGAACTTCGCTGGAGAGGGCCTTCCTTTGTACATATGGAAAAGCCTTGCGGCCAATGGTCAGGATCCTTGGGACATCGGCAAGGCGCGCCAGGCAGAGAAAGCGCGGGAAGGTCAGATCGCCGTGGTGGACCTTGGCCAAGGCGCGGTCGCATGCCTGACCGGGTATGTCATTGGTAATGAGCCGACGGCAATCGGGGAAGATTTTCCTGCCCTGTTTCGCCCTTTGCAGGAGTTGGAAAATCAGGCCCTCGACAGCTGGTACGTAAATGTGCTGGCCTGCTATCCCACGCACCGCGGCAAGGGGATTGGATCGCAGCTTCTGGATCTGGCGGATGAGATAGGACGCTCCGAAGGGGTGCGCCAAATGAGCATTATCGTGGCGAGTAACAATACCGGAGCTCGACGGTTGTACGAACGTCATGGATACGTCGAGACAGCAACCGCTCCTTGCATCAAAGAGAACTGGGCGACCCGCACCGAGAAGTGGGTTCTCCTGCTTAAGCGCCTCTAGGCCAGATTGGCGGCTTCATCCCGCACGCTACCAGTCGCGCTCAGAACGTTTTTGCAGCCGCAGCGAACGGCCGGAATGGTGCGCCGTACCTCGGCACTGCCGTGGGTGTGCGAAGATCGGCTCAGTGCCGGGAGCGGCCTGGTGCCAGAGATAAGGCGAGCGTCAGCTGTGCGGGACGGAGCTGCTGTTGGTTTCTTCGACAAATACCGGGGAGTTAGATAAGAGTGTCGGCGACGATACCGCCACAGGAACCAGCGACCCATGCCAATGCCGTGGACATATCGGCACGCCTCCAAAGAATGGCGCGCTTTCCTCGATGACGTGAAAGAGCGCATGTCCCTCGAGTCAGACAATATGGCTTACACGGCGGTCGATGCGGTCTTTCAGGTGTTCCGGCGTCGTCTGACCGCTCAGGAGGGCTTGAACTTCGCAAGTATCTTGCCAAGCGTGCTTCGCGCGATCTTTCTTCAAAACTGGGATGTTACGGAGCCTCGCGCGGCGTTTGAAGACCGAGAGACGCTCATCTCGGAAGTCAAGGAGGTGCGGGTGAACCACAACCTAACGCCGGACAATGCGATTGAGGCGACGGCATGGGCGGTTCGGCGCTGCACTAACGGAAGAGACTTCGAGCGCGTTTTGGCCAAGCTCCCGGCTGAAGCGCGCGCCTTCTGGCATGTCGACGTTGCCGATCCTGCCGAGCTGGAGCAACGGATCATTTAGCGGCTTTGCACCATTCAGAAGGTTTGGGCTCATTTTAGTCGTTCGCAGCAAGGTGCCTGAGACCTAGGCAGGGCATTCCGGTACATGAACCGTCCAGCCGTCATAGACCACCATCGGTGAGAGCGGCGGCATTATGCAGGCTCTTAGGTGCGCTGAGTAAAGACGAGATGTCGGCAAACGGGAACGTGGCCACCGTCACTGGACAATTCTGCCGTTCGGTGTGGCATGCGTCGACGTTTGTTTTGCTGAGCAGTTAACAAAGCTTTTCAGTCTTCAGATGAGGCCACCATATCTCCTGCATAGGCATCCATAAGCTCCGCTCCAAATTCTTCTTCACCTTCGCCTCTGAGAGCCGAGATACTTGCAAGCGCTTCATCGCGAACTGACCGGTTGGGGTATACCGTTACAACAGCAAAACGGTCCAATTCCGTGTCGACGAGCATTGAGCGCTCTGCGCCCAGTGCAATGAGCCCAGGAAAGTATTTTCGTAACATCAATTGTTTCACATGCTCGAGGTTCTCAGCCTCGCCTACCATTCGCCATGTCGTGATGGAAACAAAGCTCATTCGACCTTCCTCCGCAAAATGAACATAGCACATATTTGAGCCCCGGTCCCTTTCGCAATCGCAGTCAGGCTTTGCATGGCAGTCCTTGTTCGAACTTTGTTGCGCCGCGAATAAGATGCGAGAAGCGCCGATCGCTTTGAATAGCTTGGGTGCTTGTACTCCGGCGGCAACCACCTCAACGTGACAGCCGCACCAACAACCCGCGCACGTTCGAGACGTGCCATCGGCCTCCCCGTCGAGTCATTATCCCGCGGTCATTCAGCGCTCCCGCGATGCCTCGGAGTGTCGTCACGTCGTTCGCTTGCAGGCCCTGGATCACTGGCGCCAGGCCTTCTGCGAACGCATCCGCATTCGCAGCAACTGCCGCCCTTAAGGCTTCTCCACCCTTCCCCGCCCGCCTGAGCGCCGCAGCCCCGTTCGGGTTGCCCAGCTTCACCCCGCGCGCCTTGGCCGCGGCCAGCGCCTCCTTCGTGCGGCGTGAGATCGCCTCCCGCTCTTGCTGAGCCACCAACGCCATGATGCCGACGGTCAGGTCATTGGCGTCGGGCACGTCACAGGCGAGGAAGCGGACACCACTGTCTCGAAGTGTGAGCAGGAAAGCGGCGTTGCGGGAGAGGCGATCGAGCTTGGCAATGATGAGCGTCGCCCCAGTCAGCCTTGCAAGCTCCAATGATCTTTGCAGTTCTGGCCGATTATCCCTGCGCCCCGACTCCACTTCGGTAAAGCGGGCCAGGACCTGCGCGTTCTTTTCCACCGCAAAATCGTCGATGGCCTTGCGTTGGGCGTCGAGCCCGAGCCCGGATCGCCCCTGCCGCGCCGTCGAGACCCGCTCGTAGGCGACCAGCTTCAAGAGTGAGACAGTGTGGCTGACCATGTACAAACCTGCCTAACGTTGGTTTGGCAGTTCTGTACGATGGAAGCCTCGAAAAGTGTAGGCAGATCAGTGCTTTAATCGCGCCGTCCAGGCTTGTGAGTGACTCTCACGGGTTCGCGTGGGGTGTCTAGCTCCGTTTCGTCGTCCGGCGAACCCTCCTCGACGTTATTGCCGTCCTTGTCGGTGTAGACTGTCACGAACTTGATCGTTGTGACCGGATCTTTCATCGCAGCCGTCTCGGCCATGTCCACGCGCGTGCGCGCCACCGGTGTCAGGCCCAGTTCGGACATGTAACGGCCCATCAGCTCCATCTGCTTGTTCGCAACCGTCAGCCAGGGCGACTGCTGGACGTACCCGCTTGGTGTCTTGAGCAGCGCGGGCCCCTCTCCCAGCTTTTCTTCCGCCTGCACCCAACGGGCGTAGGCCTGACAATAGGCCGCGAGGGCCGCACGGTCTGCAAGAGTCAGGATGCCCGCTTCGTGAAGTGGCGTCGCGAGCCTGCGCCATTCCTTTCGAGCCACGTCATTTAGATGCGACGGGCACCGCGGCAGGGCGTTCAGCGGTGAGTTGGACAACGTGCCCGCTTTGGGCACGGGCTTACGGCCGCGCATCGATTCCATCCGAGCGGGCTTTGATCGCGCTCAGCCAGGCCATCAAGCCGCCTCCACCTGCCGTCTCGATGCGACCTCCTCGAAGCTGCGGCCATCCTCATCTAGCGTCGCCGTCTCGCCAGTGAAGCTTTCCCAGCGTCGCACAGCTACATCCACATAGGCCGGGTCCAGTTCCATGGCGTGGCATACCCGCCCGCAGGTTTCGGCCGCAATAAGACTCGTCCCCGACCCGGAAAAGGGTTCATAGACGGCCTGTCCGGGGCTCGAGTTGTTCAGCATCGGCCGACGCATGCATTCCACGGGTTTCTGCGTACCGTGGATCGTCTGGGCGTCCTGGTCCCGGTTCGGAATCTCCCATAGCGTCGATTGCTTGCGGTCGCCCGACCAGTGTCCCTTGCCCCTGACGCAATACCAGGCGGGCTCGTGCTGCCAGTGGTAATGTCCCCGCGACAGGACCAGCCGCTCCTTGGCCCAGATGATCTGGCTGCGGATCTCGAAACCGCTGGCGACCAGGCTCTCCGCAACCGTGCCCGCGTGCAGAGCGCCATGCCAGACATAGGCCACGTCCCCGGGAAAGAGCGCCCAAGCCTCGCGCCAGTCCGCTCTGTCGTCATTGGCCACCCTGCCCGTCCGCTTCGTTCTGGTCGCGCCGGTCTCGTTGCGCCAAGCAGGATCGTAGTTCACGCCAAACGGCGGATCTGTCGCCATGAGATGCGGCCGAACGTCGCCCAGAAGACGGCTCACATCATCCCGGTTCGTGGCATCCCCACAGAGCAGCCGATGGTTTCCGAGGCGCCACAGATCACCCGGGCGCGACACCGGGTTCGCCGGCGGCACCGGCGTTTCCTCTTCGCGCGGGTCCGCCGAGCCGTTGTCCAGCAAGGCATCGAGTTCAGCGCCCTCAAAGCCAAGGTCAGACAGATCGACGCCCAGCTCGGAGAGGTCTCCCAGTTCCAGCGCCAGCAGTTCCCTGTCCCACCCTGCCCGCTCGGCCAGCCGGTTGTCCGCCAGGATGTAGGCCCGCTTCTGTGCCTCGGAGAGATGCGCAAGTTCGATGACCGGCACTTCCTTTAACCTCAGTCGGCGCGCGGCCTCCAGGCGCCCATGCCCCGCGATGATGCCGTTCGCGCCATCAACCAGCACCGGGTTGTTGAATCCGAACTCCCGGATTGACCCCGCTATCAGCGCGATCTGCGCGTCGGAATGCGTCCGCGCGTTGTTGGCGTAGGGGATCAGTTCCTCCACCGGACATTGCCGGATCGCCGTTGCGCGCCTGTCTGCTCTCGTTGCCACGGTACCCCCCGATCTTTATTGCACCCGTCTGTGTGCCTACCTCTCGGGGAGTATATCAAGCCGGATAAATATTTGTAATTGTGACAATTTCTGACAATCAACGCCAGAGAGCGACGAACCTGTGAATCGTGTGCACCTGAAGCAAGCGCAAATAAACCAGTGATTGGCGCAATGTCGGTTACCTTTAGGCACTGGAATGAGCAGATGTGTCTATCGCTACACGGCGAAAAACCGAAATACCTTGCCTCCTATTTCCGTTTACCATGTCGCAGGGTTAGGCCGACATCTCCAGTTCCGACAATTTTCTGTGTCGCTGCAGTTTCTGCGGGTACTGTTGGTGAGTAGAAATTTTCGGAGGTCATGGTGGATCTGGAAGTTTATTCGAAGCTGACTTGGGCCAAAGGTGAGCTGCAAGTGCGTGAAATAATCAAAGAACGTGACGACGTGCTGAAGAGGTTTTCTCCCGCCTTTAGACCCGCCGCTGTGGCCGACCTTGACGAGGCTGATTTCAGGGAATTCCTTAGTATCAAGCACAACAAGCACTGGACGGGCCTCGAGCGACAACCGCAGGTATATGCGAACATGAAGCGATTGCGGCAAGTGCTCAGCATTCTTGTGGACGAGTCACGTCCGATCAGTGGGCGGGTTGATAGCGCGATTAAGGCTCCTGGCATGGGGGTGGCGAAACTCTCCGCCATTTTGTTGGTGACTTATCCAGAAAAGTACGGGGTTTGGAACGGGACTTCGGAGAAGGCCCTTCGCTCTCTAGGGCTCTGGCCCGCCTTCAGGCGCGGAATAACAACAGGAGAACGATATGTCGCTGTAAATGAGGTGCTGCTTGATCTGACCCGGAAGCTTGATATCGATTTGTGGACACTGGATGCGCTCTGGTGGGGTGTCAAAGATGAGGGAACTGCCTCGAAAACCTCGGTCGAAAATGACGGCGAAGCAAAGGCGAAGGCCCTCGCGAACATGAAAAATTCGATTCTTGTCACGAACCGGTTTGCCAACGGGCAATTTGAGAATGTGACAATTAAGAGAAAAGACCTGAAGATGTCTGACAGCGAGCTTGATGCACTTTTGGCTCGTCTCTTGAAAAAGCAGGAAGAACGGTGTGCGATCACTGGGCTGCCTTTTAAGTACAGAGGTGACAAGAACATGCTACCGTCAGCAGACCGGAAAGATAGCAATGGGCACTATGAAGCGGCAAACCTTCAGCTGGTCTGCCGCTTTGTCAATTTCTGGAAGCAAGCGACTCCGGACCACGTATTCCGTCGCCTGATTGCAGCTGTGCGCGAAAGCAGTTTGTCTTGAGGCTCTCTATGCTGATCCGTTGACACGCCTGCCGGGAACACCTTTTACAGAAGGTCGGTCCTTTCGGCGCCTGAGTACTCAACCACTCAAGGTCGATCGACCACATACAAAAAAAACCGGACATTCGCTATAAGCCTCATTAAAGTCAGCTATGCGGGACAGAGCTGCCGTTGCGGGTTGTCTGTCGAATGCCCGCTCTCGGTTATTGGCGCGAGATTGACTTCAACCCGAGTAGCAACGCTGCGCCAATCATAAAGCCACCGCCGATCCGTTCGATCCAGACCCGTGCGCTGCCCTTGAACCGTTTGACAATCCAACTCGACCCGAGGCCATAGGCAGACAGGAAGAGCCCGTCCATGACGATGTAAGTTGCGGACAATATCAGAAACTGGGGCCAGAAAGCGGCGTCGCTCGTGATAAATTGTGGGAAGAGCGCCGCGAAGAAAACAACGGCCTTCGGGTTCGCAGCGGACGTCAGGAAGCCTTGGAGCCATAGGGTCCGCAGCGATGCTTTCTTCTGTTCTGAAAGCTCGGCTGATTCATCCGGTTTGGCTCGTCGGATCATGCGGATACCCAACCAGATCAGATACGCAACCCCTGCCCACTTGATGACAGTCAGGGCTGTCGCAGAGGCCGCGATAATCGTGGCTAGCCCCAGACCCGCCGCCAGCATCTGCAAGGCGTTTGCTGAAAGGTCGCCTGCGGCGGTCCACAACGAACGTTGGAAACCATAAACGCCGCTGTTGGTAAGCATCAACAACTGGCTTGGTCCAGGCGTGCTCATCAAAGCCAGAACTGTCAAAACATACAAAGTCCAAGTTTCAATTGGCATACGCTGGTCTCCTCCACTTCACTGCAGGCTTGAGTTTGAACGAAAATTCACCCAGTTGGGAAGCGCTTTCGCACCGCGCGTTCGGGGATAACGGTCATTGGTACGCAGCGCAGCAATCGGAAAAATTGGGCTCAAAGCTGAAGTTCGCCGCGTGTTTCACCAACGACCGCTGACAGCATCATTCTGACGCGCGCGCATCTAAATTCGCCATCCAGACAGTTTTCCAAGGGCAATTTCGAGGAGACATCGCACTTGTGCTTCGTCACCAGCCCCCCACCAGGCCCGCTGCCAGCACCGGCCCCGGCCGTCACGTCGATAGGCAGCCGATTTAAGGGTCATTTCCCTATAAGAACTATACATAGGGTTTTGACCCTTAAATGCTGACCTTTTAAACGCCAGCTTCGCCTCATTGGAGTTGCCGAATAGCTCTGGATGCAAAGCGGCGGCATCCGCCGGACTGTCCACAGCCACGCTCGCCAAGAGCATCTGCTGGAACAAGTATGGCTTTTCAGCGTCCCAGGTCGTCAGGCGGTCATAAACAAGCGGTAACGCCACGTCTGCCAGTATGTGCACCTCCAGCGGATTGGCGGCAGATCTGTTCACACCGCGCCCTCGGCCGATTGCCTGCACCATTTCATCGTCGCAGATTGCCGCGCGCAGGGTCTCTGCAGTTCCATCTTTATGCCGAACCGCGGCGAGCCCGCACGTCCGACCTGTGCGCATGTGCAGTCCGACACGATCCGAGACATAGCCGGACTCTTCGACGCCGCCGAACAGCACTCTGGCCAAGTCTTCGGTTTCCTGGCTCGGAGGAAGTGGCCGGCCAATGCTGATGAGCATCACGACATCCTTGTAGATGTCGAGCCCGGCGACGGCGTTGAAATGCGCCGTCACGACGTTCGGAATATCACTAAATGCATCCTCTATGGCTTGGTAAGTCACCACCAGCACATCGCGCGGAAAAACCCGGAGCGCATGCCAGCGCACATAATCCACGCATTCCCGCAGACGGTTTCCCCTGCGCTTGAGTTCTTCTGCTGGAAGGCCCGGCAACGGGCAGATCATGGACTTCCCGAAGCTCCCCGTGACCTGGCGGAGATGCATGTGCGGCGCCGAGACGTCGATGCACTCGATCTCCATCGGCGGCAGGATCGCTTCTGCGAGGCTCTGTCGAAGCGTCGCATCGAGGTGAAGGACAGGTTTCCCTCGCAGACTGTCATGCACGCGCTTGACCCGCCGCATCTCGATCGCCTGCCGGCCATCTGACCCGGCCGGGCGCACCTGCAGGGACTGCCCCGGTTGCTCGCCATGGCGCAGCAAATCGGCCAGGGCGCGCCAGAGGCGGCTTAACAGGTCGATCCTCTGGTTTGCCTTGGCCGTGCGCAGGGCTTTCGCGCGATGGGCTCTGTCGAGCCCAGGCATAAAGGCCGCATCGGTTTTGCGCCACTCTTCCAGTTTCGCCGCGTGCTGGCAGTCCTCATACGTCAGACCTTCGGCGCGCAGACTGCGGATCAAGGAAATGCCTTTTTGCCCTTGGCGCAATGCTCGAGCGGCAGCCTGCCGGAAAGCCGAAAGATCAGCCATCGCGGCGACCGGCGATCCGCCCACCCTGTTCTCGCCCATCCTATGGAAGGGCTCGTCGAGCAGATCCTCAACGAACAGATCTGAACAAGTCTCGACAGCCCGCTGCCAGCACCCTTCGTCGACCAGGATGAGCCCAACATTGTCTTCCGAGAAAGCAAGGCCGGAAAACAGCGTATCATAGGGCGCCACGACAACGTCTGCCGCGGCGACGTCCTTGCGGTTCTGCTGCTTGAGGCAGCTATCGAAGTATCTACATTGGTTGCCTTCACGCGACCGACAGGCGTGGTCCTGCACGGAAAGCCCGCTCGCGAGAACGGCCCGAACCATCTCGATATCGCGACACATCGGATCACCAGTTGCCGGGTCCTTGCGCTCGTAGCCTCGGAGCACCGCCGCGTCGATCCCGAGGTCGCGCCCGGCGCAAGCGGTTTCCTCAGCCAGGGCGTGAGACGGCGTGAAGACGAGAATGCGATGCGGCAGGCCCTCGTTGCGGAGCGCTTTCTTCATGTCCCTGATCGCTGCGCGCGCGGCGCGGGACTTGCCAAGACCTACCGTCGCTCGCACGCCGAGCGACGGTGGTTCTTCCTCGTGGATCCGGTGCCATGCCAGAACTTGCTGACAGTAGGCTGACAGCAGCTCCTGCAAACGCGTGCGGCCTTCTTCCACAGACAGCGCGGCTGGCGTGTAATCCGGCGTGGGCGTGGAGATCTCCCTGCCGGGCAGCCGACCCTCATCCAGCAGGCGCAGCTTGTCGGCGACCTTGCGTGTGGCGTCAGCCACATCAAACGCACGGCCGGTCGACGAACGCGGGCGATCAAGATCGGTGGTGTTGGCAAACCGCTCCCAGACGAGGGAGGCAAGGGTAACTGGGACCGGCGTTTCACCCCGATCGAGCAGATCATGCACACTGTGGAACGCGATCTGGCTCAGCCAGGCATCCCGCCCGTCCACGACACGCCCGTTGCGGCGGATGACCTCGACCGGGCCTGTCGCCGCGCTTGGTGCACTACTCTTTGACCGCCTTGCGCCCCACTGCGGTCCAGGGTGAACTTCGGCCAGAAAGGCCCGTGCGTCGTCTTCCGTGATGAGGGGCAAGTCGTCGATCTTGCAATCGAGGACTGTCTCACCCATTGGCCAGTAATAGGGTTTACCGGTGCCGGAATGAATCCCGAAGGCCACGAACTGTTGACCGGCACCCAAGATCTCCACGGATCCTGTTTTGAGCTTTGGGAACGCATGATCTGCCCGGTAGAGCAGCAGTCGTTTCGGCCATTGACCGACCCGGACGAGTGTCGTACCGAACCGCGCCTCCGCCAGCGACTGGACACGGTGGGCCTCATGTGCGTCCAGGCAATCGATGTCGAGCCCGATGAGCCGTCCCGTGCGAAGGCCCACGCCGCAATTGGCGTGCGTACGGCACCATTGCGCCACCTTCGCGTCGTCGATCTCCACGCTGGACCAGCGTGTGACCGCGGGCGCTTTCCCGCCCATCCGGATAGGCAGTGGCTCGAAACCCTGCGACAGCAATTGCTCGGCGGCCAGCCCGAATGTGATGTGACCAGCACCAACGGGGCCGCCATTGGCAGCCCGGTTGCTGTTTTCGTTTGTCTGTGGAGCCGGAAGAGTCCGCTCCACGCGCATGGCCTATTGCGGGTCCCTTTGCCGGCGGCCCGCTTCCTCGAATGCCTCCACGTCCGACCGGCGATAGAGCACGCGACCGCAGATCTTGAGCCAGTCAGGCCCCCTGCCCTGCGCGCGCCAGCGCTCCAGCGTGCGGCGGCTGACGCGCCACCGAAATGCGAGATCGTGTTGCGTGAGGTGCGACGGCATGTGTTCGGTCATTGCCCCACCCTTTCCCCGTCACGGCTTGCCCGGTAGATCGCGAAGAGCGGCGTGCCCTCCTCGGTCGGTTCGACGTAATGCACCTGGTAGTCGTCACGGCGGTCGATGACGAAGGGTAGATCCCAGAGCCGGTATAGCCCCGGGATCCGCTGATACGCCTGATCCTCTGTTTCCATGTGAAGTGTCCTTGCTTGAGTCTTTGAGGTGAAAAGCCACTCCGGAGGCCCGAATGGGACAGTCATCAGGAAAGTTTTCCGTCGAGGGCGCGCAACTTCGCCAATGCGCGCTGGTAGCGCTTGCGGGCCGCGTCGTGGCCCATCCCCAACGCCCGCGCCGCTTCCTTCTGAGTAAACCCCATCAGCACCACGGCCACCACGAGACCGGCATCCTGGCCGATCAGCGGCTTCAATCGTTGCAAGGCGAGATCCGGAGAGGTGTTCGGCGGCGCCTCCGCCGCGGCGATGCTCTCGTCGAGAGGCGCTTCCTTGCGCGCCCAGTCTCGCTTGAGGGGCCGCATGATATCGCGGCGCACATTCATCAGCAGTGTTGCGGCCAGGCGATCCACGCGCGCGAGGTCGACGCGGGCGATGGCCTCCGCCATGCGCGCCGAGAGCTCCGCGCAGAGGATGTCGGGATGCTGTCTGTAGTAACGAGACAAACGCCCGTGCAGGGCGTCGAGCCCGGGCCAGAGTGCCAGCAGTACGAGGATCCGCGCTGTGTCTGCAAAGGCGGCGTGTGATTGCGCCGCCGTCACCAGCGCCCGCAGTGTTTCGTTCTTCGTGTTGGGATCGCCGTACCGTGCATGCTGGTGTTCCAGCAACGCCGGCACGTCCGGAAAACCTGCCAGATCGGGATGTTTGCTTTGAATGTCGCGGAAGTAGTTTGTGATCACCAGCCGCTCCGTCTGCCGGAGAAGCTGCGCGTGAAGCGCGTGCCAAGAGGCTCGCATGAGACGCCTGCCTTTCGGCCGGGCGTCAGGCGCCTCATCGTGGCCAGGTCAGGGCGTCGCGCGCCTCTCGGATTGAAAAAGAAAAGCGTGCGACCGTCAGGCCGCCCGCTTGGAGATCAGGTTTCGTTCAAGGTGTCGCAGCTCCGGCACACCGCAGATGCAGGGCGCGAGATGCGGTAGCGGTGCCCGCGCGCGAACTGCACCAGGATCGCCGATCCGTGCCGGCGGCCGAGCAGCTTGCCGCAGCAGGTGCAGCGCCAGTCGGCGCTGACCGCTGGTCCGCTCGTGTCATGTGCAGAAACTTTGTACTGGATGGTGGTTCGTGTCGTCATTTGTAGGCTCCTGACATAGTGGAGCCCGTCACATGACGCTTGGAATCAGAGTTAGTCAGACCCCGTGACCGGAGCCGGACCGGAGTTGAACGTCAGATGGCAATCTGCCATTTGCCCTTCCCAGGACTTCGAAGGAATTCTGCTTTCAACTTGTTCCAAAGCGGTTGGTTGAAGATGTTCGCCAGCGACTGGTCCTTGGCGATCCCGTCGACAAGGTCGGCCGTCGCCATCGGCATCGGGCCAGAGTTGTGGGCATCGACCAGGCGCTGAATAACTACGATGCGGTTCTCACCCTTAATATCGATGGTACCTGTACCTGGAACAAATAGGATTGCCATGTTGTCGCCAACGCGGGCAAGTTCCACGGCCTGTCCACCTCTGGCAAGCAGTCGATGTCGACGAAATACAGACCGGAGCTTGTCTGCAACCAACGCGATTTCCGGTTGATCACCTTCGATCTGATCGGCAAGCGGCGTCATTACATTCGCGGCCAGACACGGCCCCGCCGCATTTCCTGCCTGAAGGACGAGTCCTATCCCGAGGTGGTGGCGGGCCCGAAGCTCCGTATCGACAGAGGACCTTATCTTCTCATTATCAATACAGCGAACGAGGTAGACCGGAACATCCCTCTCGTCGACGACAAGCATTCCGAGGTAGAAAAGGTACTTGTTGATTTCTTCGATGGCTGGCGCATCCAGTGTGCCCTCAAGGCGCTCCTTCAGGTGGTCTTCGACCCAACCGTTGCGCACCCTGTAAAGCCTGTAGTAATCCGGGATTCCCGAAGCTACGTGCCCGTCCGTAATGGTTAATTCTGCCACTTTGTAGTTTTTCGAGTCTGCATCTCTCTGTTCGACCTTGACGTCCACCCCGGCCACTACAGGACCGATCTGGTCCTCGTCATCGAGCAGATCGTCTCCCTCCCATCCGACAGGCACCAGAAAGCCCAGCTCGGTCAGAATGCCCGGATCTACCTTACGCGCCTGAAGCCACGCGCCGGATACATTGTCGCGCCCGATGTCCCATATGGCCAACAACGCAGGGATGACAGCCGTACTCTCCTTATCGGTGGGCGCGCGGCCCTCGCGGAGGATGTTCCAGTGACGCAGCAGACGATGTCCCAGTACCCGTTCAAACGGATCATCAAGGCTAAGAAGGCTGCTGGTGTTGCGATCGGTCAGCGTGAAGTTGAGGGTTTTCACCTCTGCACCAGCCCGGCGATACCGAACCGCGATTTCGACGAAGCGGATTGCAACTGCCTTTTCGAAGGTCTTCGCGAGTCCCGGCTGATCGTCAATGATCTCAGAAATGGACTGATCGATCGTGGTGGAGAGCGAGAGACGGTTTGCCAAATTGCCAATGCTAATGTCCGCACGGATGACCCTCGCGCGGTCAATCACAGCCTCCTCAAGATCCGGCAGCTCCAGGTCGAGCTCCTTCAGGAAATGCGAGATATCATAAGCCTGAAAATCTACCGGCTGATTAGAATAAGTCTGGTCCAGCGCCGTTTCAACGAAGCGCTCGGCAATGGTGTGCCGTAAGTTTCTGTTGCCCGCTCGAACGTGAACACGTCCGGTGGACGGCGTATAGACGATCATCGCCTCTCCGGGCGGCCGAAAATAGATGCTTTTGCGGTTGCCTTCGTCGTCAATCTCCCGAACGCTTGCAGGCGCATTGGGATGAAAGAGCAGATACATCTCTGCGGAAGGTTCATCTCCATCCTCGGGTATTTCAAATTTGTCGATACTGTAGCCTTCGCCACGATCAAGCTCGGCGTTGAGGTCCGCGAGAAGATCATCGAGCACTTTGCTACCTTCCTCAGGCCCACCCTCGATCGAGGGTTCGGCCATGAAGGTCTGATAGTGTTTGTCGTAGCGGCGATATAGACGCAGGTGCAGACTATTTTCCACGGCTTCGAATAAGCCAGGATCATTGAGAAACAGCCAAAGACTTCTGGCAAGTCGATCTCTCTGATTTCGCAAGTCCATGGCGCGTTGGGGTTCTAGTCGGGTGCGTGCCAGACCTTCCAATACATAATCGCCTCTATCGCTTGCCACCGTGACGATTCTCGCAGCCTGTTCTTCGAGTGGGCTGAGTTGCTGCTTGGTCTCTGTTCTGAGCATGCTGCTTACGTCAATATCGACGTCCTGTTCCCAACCTTCAGATTTGTAGGGGTCGAGCCACTTGAGGCGGTCGAAGACTCCACTTCGAAGAAACGCCGCCAGCAGTTCTGGCTCGGCGTCATCGAACAGACGAGATAGGTTTGGACATGTCTTAGCTGGCGCACGTACCAAGTCGTTTCCTCAATGCCTTTTTCATAAACTATAGGTTGTAGGTCGTGCCGCACGCAAATTATTGGGAATTGAACGTCCCAACGGGCCCCTAAAACTGGCTTTTCTCCGAAAAGGAGAAACGCATGAAACGGCCCAACCCGCTCAATCCGTCCCACATGAAGGCAATGGAACGCCGCGCCGAGCTATGCAAGCTCCTGGCGCTCGGCCTAGTCCGCCTGCATCAGCGCCAGTCAAGCGAAGTATCTACACGGATTTGAGAAAGTTCGCTTCACTCTCCGCCCGACCGGAGCGGTCATGCAACCGAACCAGGAGGACACGCATGACAAAGCAAGACCCGATCCCCGCACGCCTGGCTGCACTGAAGACCGCCTCGACACCGGAACTGAAGGCGCAATGGCGCGACCTCTTCGACAGCGAGCCGCCGCCCTTCAACCGCCGATACCTGGAAAGCCGCCTGGCCTACCGCATCCAGGAACTGACGTATGGTGGGCTGAAGCCGGAGACCATCCGGCGGCTGGAGCGGCTAGGCGAGGAACTCGACGGCGGCGATCGCAAGAAGAGCCGACGCCGTGCCGATCACGGCATGCCCATCGCCGGCACGCGCCTCATCCGGGAATGGCAAGGCGTCGAACAGGTCGTCACTGTCACCACGGATGGCTTCGAGTGGCAAGGGCGACCCTACAAGTCGCTATCGGCCATCGCCCGCGCCATCACAGGCACCCGCTGGAACGGATGGATTTTCTTCGGGCTCAAGAACCGGAGGGCTCAGACATGACGAAGCCAGTTATCCGCAAGCTGCGCTGCGCGATCTACACCCGCAAGTCCTCCGAGGAAGGGCTGGAGCAGGAGTTCAATTCGCTCCACGCTCAACGGGAAGCCTGCGAAGCGTTCATCGCAAGTCAGCGCTCCGAGGGCTGGGTTCTGGTCCGCGATCAGTACGACGACGGCGGCATCTCGGGTGGCACGCTCGACCGCCCTGCCCTGCAGCGTCTCACGGAAGACATCGAGGACGGGCTGGTCGACGTGGTCGTAGTCTACAAGATCGACCGCCTCAGCCGCTCGCTCACCGACTTTGCCAAGCTGGTCGAGGTGTTCGACCGCAACGGTGTCACCTTCGTGTCGGTGACGCAGTCCTTCAACACCACCACGTCCATGGGGCGGTTGACGCTAAACATCCTGCTCAGCTTCGCGCAGTTCGAGCGCGAGGTTACGGCTGAGCGCATTTGCGACAAGATCGCGGCATCTCGGCGCAAAGGCATGTGGATGGGCGGCGTGCCGCCTTTTGGCTACCGGGTCGAGAACCGGAAGCTGCGGATCGATGAAGAGAAAGCCGAACACGTCCGATGGATCTTCGCTCGTTTTCTTGAAATCGGCTCGGGAACAGAACTGGCGCGCGAAGTCGATCAACGCGGAATCCGTACACCGCGTGGCAATCGGATCGACAAGAAGTACCTGTACCGGATGTTAAACAACCGCGCCTATATCGGCGAGGCGGTCCACAAGGGCGAGAGCTACCCCGGCGAACACGACGCCATCATCGACCGCGAGACTTGGGAACGGGTCCACGCCATCCTGAAGGAGAGCCCGCGCAAGCGAGCCGCCCGCACCCGCGCCGAGACACCTGCCCTGCTAAAGGGGCTGCTGTTCGGGCCCGAAGGTGCGGCCTTCTCGCCGACGCACACCCGAAAAGGCGAAAAGCTCTACCGCTATTATGTCAGTCAAACAGTTTTGAAACATGGTGCCGGATCCTGCCCGGTCGGCCGCTTGCCGGCAGGCGAAATCGAAGCGGCCGTCATCGACCAGTTACGCGCCGTGTTTCGCCAGCCTGAAATCGTGGCAGGGACATGGAAGGCGGCACGTGGCCATGCCGATGACATTGCCGAGGCCGACGCCCGCACTGCCCTGCAACAGCTTGATCCGCTGTGGGACGAACTCTTCCCCGCCGAGCAGGCACGGATCGTCGCGCTGCTGGTCGAGCGCGTGGAGATCGGTACGGACGGATTCAACGTTCGCCTGCGCGTCGATGGCCTCGGCGGCCTCGCGCGCGAGATGCTGTCCGATGGGATCGGAGAGGCCGCATGACACGCGGCATGCCGATCCCCGAGACTGTCACGCTCCATGTCCCGTTCCGCGTCGTGAAGCGCGGCGAGCGGAAGGAGATGCAGATGCCGGACGGTGCCATGCAGCCGTGCCGGACAGACAGCACTCTCGTCAAGGCGCTGGCCCGTGCCTTCCGCTGGAAACGGATGCTGGAGTCGGATGAATTCGCCACCATCGCCGAACTCGCGCAGCGAGAGGGCATTGCGCCCTCCTATATGACGCGCGTGCTACGGCTCACACTGCTAGAGCCAAAAATTGTCGAGGCGATCCTGGACGGGATCCAGGGACCGGAGATGACGCTGGCGCGGGTGCTGGAGCCGTTTCCGGCGGAGTGGAGTTTGCAGACAGTCAATCACCGGTAGTCGCTTGTTCGACATTCGCTTGGCATGGCGGCTCGCCCCTGCGACAGTCCCCTGATCCGCCCTGAATATTGATAACGAAGATGACAGAGATAAGGTTTTCAAGCTTCCCGCGCACGACGCCGCCTCCTGAGTTTACCACTGACTTGATCAATGCCTTCGTAGAGGTTGAACAGGAGATTGGGACGCAGCATTTGGAAAAAGGTCTCACCAGCGATGCCGTCCTAGAAAAGCTCAGACCAGCACTTTTGAAGCTCGGATTTGAGGTCGAACATAGTAAAACGGCAGATGGCAAAGTTCGCAGACCCGTATTCTTCGGGGAGAATGGCGCTCCCGACCTTCAGTACGAGATCGACGCATTTCAACCTAGTTGGGGCTGTGGACTGGAAGTGGAGGCTGGCCGTGCATGGATGGGCAACGCAATTTATCGGGACCTTATCCAGGCGCTGGTAATGGACAGGTCGACGTTTTGGCTCTAGCCGTACCTATCGGGTATAGATATCGATCCAGCGGTCGCGGTGTCGTCAGCAAGGATTACACAAACACATGCGCGGTTGCAGATGCCTTGTACGGGCACAGTCGCATGATCATGCCCTATAAACTTTTGCTAATTGGGTACTGACCGAATCTCCTATTGGGGACCCATGATACGTCGTGAAAAGCAAATTCGGCCCAATGCCGACCTTCAGCTTTGGATTAGAATGCCGCATCGCAGCCCGTCAAAGCTGCCGTTCGCCGCGCTTGCGAACCCCGGCGGGGTCCGAAGGTCCCCAGTGCGGGACAAACCCGCCTTTTGCTCACGCGGCTATTGCTAGCGCAGCATTCTCTCGCCCGTGCAGAACGTTTGTTGTTGCAGTGCAGCGCAAGTCACCGAAGCAGTCATTCCACGGCGTTGATTTGGTTCGAACCGAAACTGAACTTCCGCCGCACTCCGATCCAACAACTAAGACGCGGACATCTTGTCCGGAACGTCGCGCTCAACCATGGGTGCATAGCGCGAAAGCGGACGTTCGCTGCTTTCAGGACAAAGGTCAGCAATGGGCCGTCCTTATCGCTACCCGAACGCCGCGACAGTAGAGATGCCGCGCCGCATCCGAGGTCCAGAGTGAGCCCTCTATGACATGCGAGAAGATGCAGCATTTTGCGGGCGCAGCAAGACTGCGCGGGAAAGGAGGGCCCGAAGTAGAAGTCCGCATCGCAATCCGAATGCCGCGGTGAAGCCCTTCAGACCAGACTTGCGTGCGACGAAGGTTCCCACTCCGCCTATCACTAAACTAGATCACACCGCGTGCCATCAGGATATGAAATGCTGAGCCGATGAGCGCCAGGAGCCAGCCCGCCAGTAGCGTTGCGGCCAGGCCGACCTCGTCCAGCATCACGCCGATCAACCGCGTCAGGTCGGCGCCACGTCCGCCGGTAACAGCGGTTGCCGGATCGTGAGTCACGCAGGCAGCGGTAAGCAGGCAGCCCAAGGCGAGATAGGCGACCGCAAAAACGTAGTGCGTCTGGCTTCCGCTTTTAGGGAGAGGAATGGTCATCGCCAGTCTTTTCCAGTCTGTTGGCGTTCGGTTGTGATACCACTGATTCGTCCTAAATATGGCCATCTTGCGGAGCATTGTGGTCTAAACGATGAAAACACCGTTGCCTCCGCGATCTAGCGGGAAGCAGCACTGCATTCGTTTGTGCCGCTCTAAGGTGTGAGTGGGCGGGAAGCCATAGCGGTTTGCACTGCAATCTTGGATTATCGGATACCATGGAACACTCAATAGGCGACAAGTACGGTAGCTGCTGTTTATGACGCAAGCACAGACTTTTCGCGTAAACGGTGAATGACCACTTACAATCAGGCCTTCCAATTCCTTCGCAAGAGTAGCAGGGATTGAGCATCTCCGGCGAACGGCAACTCTGCCCCGCGAAGGTTCGACCGTGTCGCGATTTTGCGCCAGCAGCGAATGACAGGAAAGCGGGCTGCAACCGCAGAAGTTCGAAGACACGGTGAAAGGCAGCAATGGGCCGAAAGCGTCGGTTGTAGGGGATCTACCCTACGCCCGCTCCGTCTCGCGACCTGGTCCTTGCCCTTCGTGACCTCGCTGCTTGATGTTTGAACGGCAGGTTGTCACGCTGCACCGCGATACCAAAAACTGAGCAGATGCAGAAAATTCTCTGCCGGGTGCGCGCGCAGCGAAATATCGTCACTTCTGCTGTGGGCTCGAAGCGGACCTCGGATGCGACGCAGCATCCTGTGATATATTTGCATCGTCAACGTCGGGTTGTCGTTGTGGGAGGGCATGGCGGATCGGAGGATCAGTCATGGAAACACCAAACTTACCAGCCATTCGTGCGCTTCGCCCGGCTTGGAACAAGGGACGCATCGTCGGGCAAAAACGGCCACTGAAACCAAAACACGTCTGGGCAATCCGCGTTCGACTTGAATTGGCAGAAAATCACCGTGACCTCGCCCTGTTCAACATGGCGATCGACAGCAAATTACGCGGCTGTGACCTGGTAAAAATGAAAGTCGTCGACGTCATGGCGTCTGGTCAGATCAAAGAACGGGCATCGGTGCTACAAAGCAAGACACAGAAACCTGTGCGGTTTGAGATATTCGAAGGAACACGCGCCTCTGTCAAAAAATGGATGGAAGACGAACTCATGGTCGGCTCGGAGTACCTTTGGCCGGGTCGGTTCCATGAACGTCTGCACATCTCGACACGCCAGTACGCCCGGATCGTCCGGGATTGGGTCACGTCGATCGGTCTGGAAGCAAGCGCATACGGAACGCATTCGATGCGGAGGACGAAAGTCACACAGATCTACAAGAAGACCGGTAACCTGAGGGCGATCCAGCTGCTACTTGGGCACACCAAAATGGACAGCACCGTCCGGTATCTCGGCGTTGAACTGGAAGATGCCCTTGCGATTGCAGAGGCCATTGAAATCTAA

Protein sequences of DBSCAN-SWA_1

>NZ_CP045410|371527:401188|383564_383864_-|WP_152495644.1|DBSCAN-SWA
MSFVSITTWRMVGEAENLEHVKQLMLRKYFPGLIALGAERSMLVDTELDRFAVVTVYPNRSVRDEALASISALRGEGEEEFGAELMDAYAGDMVASSED
>NZ_CP045410|371527:401188|400555_401188_+|WP_152495659.1|integrase|DBSCAN-SWA
METPNLPAIRALRPAWNKGRIVGQKRPLKPKHVWAIRVRLELAENHRDLALFNMAIDSKLRGCDLVKMKVVDVMASGQIKERASVLQSKTQKPVRFEIFEGTRASVKKWMEDELMVGSEYLWPGRFHERLHISTRQYARIVRDWVTSIGLEASAYGTHSMRRTKVTQIYKKTGNLRAIQLLLGHTKMDSTVRYLGVELEDALAIAEAIEI
>NZ_CP045410|371527:401188|398328_398724_+|WP_152495657.1|DBSCAN-SWA
MTEIRFSSFPRTTPPPEFTTDLINAFVEVEQEIGTQHLEKGLTSDAVLEKLRPALLKLGFEVEHSKTADGKVRRPVFFGENGAPDLQYEIDAFQPSWGCGLEVEAGRAWMGNAIYRDLIQALVMDRSTFWL
>NZ_CP045410|371527:401188|384812_385349_-|WP_152495646.1|terminase|DBSCAN-SWA
MRGRKPVPKAGTLSNSPLNALPRCPSHLNDVARKEWRRLATPLHEAGILTLADRAALAAYCQAYARWVQAEEKLGEGPALLKTPSGYVQQSPWLTVANKQMELMGRYMSELGLTPVARTRVDMAETAAMKDPVTTIKFVTVYTDKDGNNVEEGSPDDETELDTPREPVRVTHKPGRRD
>NZ_CP045410|371527:401188|374672_375781_-|WP_152495637.1|transposase|DBSCAN-SWA
MKRSRFSEEQIIGILKEHQAGFGAKELCRKHGISDATFYKWRSRYGGMEVSDARRLKALEAENAKLKKMLAEQMLDVATLKEMLGKKLLKPGSRRNAVDWAMKTKGYNQRRACALAGIEPRVYRRKTKRPQDTELRARMKELASERRRFGYRRLHILLRREGWELNWKKLYRVYREEGLTVRKRGGRKRAVGTRTPMAIPQGPNQRWSLDFMSDALEDGRRFRVLNVIDDFTRECLAAVVDTSIGGARVARELDRIAELRGYPCMVVSDNGTELTSNAMLKWQENRKVDWHYIAPGKPMQNGLVESFNGRRREECLNEHLFPSLRHACRMIAAWREDYNQHRPHSSLDGLTPREYHQRSEEDQTLNRAN
>NZ_CP045410|371527:401188|382839_383298_+|WP_152495643.1|DBSCAN-SWA
MPMPWTYRHASKEWRAFLDDVKERMSLESDNMAYTAVDAVFQVFRRRLTAQEGLNFASILPSVLRAIFLQNWDVTEPRAAFEDRETLISEVKEVRVNHNLTPDNAIEATAWAVRRCTNGRDFERVLAKLPAEARAFWHVDVADPAELEQRII
>NZ_CP045410|371527:401188|396557_397868_+|WP_152495655.1|DBSCAN-SWA
MTKPVIRKLRCAIYTRKSSEEGLEQEFNSLHAQREACEAFIASQRSEGWVLVRDQYDDGGISGGTLDRPALQRLTEDIEDGLVDVVVVYKIDRLSRSLTDFAKLVEVFDRNGVTFVSVTQSFNTTTSMGRLTLNILLSFAQFEREVTAERICDKIAASRRKGMWMGGVPPFGYRVENRKLRIDEEKAEHVRWIFARFLEIGSGTELAREVDQRGIRTPRGNRIDKKYLYRMLNNRAYIGEAVHKGESYPGEHDAIIDRETWERVHAILKESPRKRAARTRAETPALLKGLLFGPEGAAFSPTHTRKGEKLYRYYVSQTVLKHGAGSCPVGRLPAGEIEAAVIDQLRAVFRQPEIVAGTWKAARGHADDIAEADARTALQQLDPLWDELFPAEQARIVALLVERVEIGTDGFNVRLRVDGLGGLAREMLSDGIGEAA
>NZ_CP045410|371527:401188|387002_387956_+|WP_152495647.1|DBSCAN-SWA
MVDLEVYSKLTWAKGELQVREIIKERDDVLKRFSPAFRPAAVADLDEADFREFLSIKHNKHWTGLERQPQVYANMKRLRQVLSILVDESRPISGRVDSAIKAPGMGVAKLSAILLVTYPEKYGVWNGTSEKALRSLGLWPAFRRGITTGERYVAVNEVLLDLTRKLDIDLWTLDALWWGVKDEGTASKTSVENDGEAKAKALANMKNSILVTNRFANGQFENVTIKRKDLKMSDSELDALLARLLKKQEERCAITGLPFKYRGDKNMLPSADRKDSNGHYEAANLQLVCRFVNFWKQATPDHVFRRLIAAVRESSLS
>NZ_CP045410|371527:401188|392210_392390_-|WP_152495650.1|DBSCAN-SWA
METEDQAYQRIPGLYRLWDLPFVIDRRDDYQVHYVEPTEEGTPLFAIYRASRDGERVGQ
>NZ_CP045410|371527:401188|397864_398248_+|WP_152495656.1|DBSCAN-SWA
MTRGMPIPETVTLHVPFRVVKRGERKEMQMPDGAMQPCRTDSTLVKALARAFRWKRMLESDEFATIAELAQREGIAPSYMTRVLRLTLLEPKIVEAILDGIQGPEMTLARVLEPFPAEWSLQTVNHR
>NZ_CP045410|371527:401188|392455_393106_-|WP_152495651.1|DBSCAN-SWA
MITNYFRDIQSKHPDLAGFPDVPALLEHQHARYGDPNTKNETLRALVTAAQSHAAFADTARILVLLALWPGLDALHGRLSRYYRQHPDILCAELSARMAEAIARVDLARVDRLAATLLMNVRRDIMRPLKRDWARKEAPLDESIAAAEAPPNTSPDLALQRLKPLIGQDAGLVVAVVLMGFTQKEAARALGMGHDAARKRYQRALAKLRALDGKLS
>NZ_CP045410|371527:401188|396105_396561_+|WP_152495654.1|DBSCAN-SWA
MTKQDPIPARLAALKTASTPELKAQWRDLFDSEPPPFNRRYLESRLAYRIQELTYGGLKPETIRRLERLGEELDGGDRKKSRRRADHGMPIAGTRLIREWQGVEQVVTVTTDGFEWQGRPYKSLSAIARAITGTRWNGWIFFGLKNRRAQT
>NZ_CP045410|371527:401188|393587_395786_-|WP_152495653.1|DBSCAN-SWA
MVRAPAKTCPNLSRLFDDAEPELLAAFLRSGVFDRLKWLDPYKSEGWEQDVDIDVSSMLRTETKQQLSPLEEQAARIVTVASDRGDYVLEGLARTRLEPQRAMDLRNQRDRLARSLWLFLNDPGLFEAVENSLHLRLYRRYDKHYQTFMAEPSIEGGPEEGSKVLDDLLADLNAELDRGEGYSIDKFEIPEDGDEPSAEMYLLFHPNAPASVREIDDEGNRKSIYFRPPGEAMIVYTPSTGRVHVRAGNRNLRHTIAERFVETALDQTYSNQPVDFQAYDISHFLKELDLELPDLEEAVIDRARVIRADISIGNLANRLSLSTTIDQSISEIIDDQPGLAKTFEKAVAIRFVEIAVRYRRAGAEVKTLNFTLTDRNTSSLLSLDDPFERVLGHRLLRHWNILREGRAPTDKESTAVIPALLAIWDIGRDNVSGAWLQARKVDPGILTELGFLVPVGWEGDDLLDDEDQIGPVVAGVDVKVEQRDADSKNYKVAELTITDGHVASGIPDYYRLYRVRNGWVEDHLKERLEGTLDAPAIEEINKYLFYLGMLVVDERDVPVYLVRCIDNEKIRSSVDTELRARHHLGIGLVLQAGNAAGPCLAANVMTPLADQIEGDQPEIALVADKLRSVFRRHRLLARGGQAVELARVGDNMAILFVPGTGTIDIKGENRIVVIQRLVDAHNSGPMPMATADLVDGIAKDQSLANIFNQPLWNKLKAEFLRSPGKGKWQIAI
>NZ_CP045410|371527:401188|384039_384738_-|WP_152495645.1|DBSCAN-SWA
MVSHTVSLLKLVAYERVSTARQGRSGLGLDAQRKAIDDFAVEKNAQVLARFTEVESGRRDNRPELQRSLELARLTGATLIIAKLDRLSRNAAFLLTLRDSGVRFLACDVPDANDLTVGIMALVAQQEREAISRRTKEALAAAKARGVKLGNPNGAAALRRAGKGGEALRAAVAANADAFAEGLAPVIQGLQANDVTTLRGIAGALNDRGIMTRRGGRWHVSNVRGLLVRLSR
>NZ_CP045410|371527:401188|376740_377736_+|WP_152498152.1|integrase|DBSCAN-SWA
MMAREFDRETERMATVVKLADIPKNHREELIREYRERSEAAFAPTTLRNFRQITHNFQVWCREHGFDPHPPIDPRAVAEYVDSLGGKVRCTTIETRLWAISEMHRAAFQPTPCRHRLVELALKGVKRKYGAWVRQAPPLCKAEVYKAIDKLGSSRLETRDKAVLWIATDSWCRASEIIALRVRDLMRQDDGSSLLFIARSKTDQFGHGAYAYLSEAGTQAVLEWIEMAKLKNDDPLVTKHQANAQVGPMDAATISRIIKRCTGRTDVSAHSMRVGGVHDAFRIGCDLSSIMVAGRWSSPEMPARYGRRILASNSAAARVSQVLGAKRQPKA
>NZ_CP045410|371527:401188|393279_393495_-|WP_152495652.1|DBSCAN-SWA
MTTRTTIQYKVSAHDTSGPAVSADWRCTCCGKLLGRRHGSAILVQFARGHRYRISRPASAVCRSCDTLNET
>NZ_CP045410|371527:401188|380702_381674_+|WP_152495641.1|DBSCAN-SWA
MAHAASFNNFITSNQAWVADGGLETDLIFSDGLDLPHFASFHVFDTEEGCATLARYYDRYIEVARSAGTGFVLDTATWRSGAFWPETVGRSLADLEAATREAVRFARDTRGRHADVPMVLNGAIGPAGDGYAPDRLYNQDAAEALHAHQVRWMAEEGIEMITAVTMTHPDEAIGLVRAASDWDLPVVVSFTTETDGHLPTGETIEWAITKTDVATGGAPVFYMINCAHPDHFAAELAGDWTSRIGGIRANASRMSHEELDEAQELDAGDPDEFGKLYGDLFQTLPRLRVIGGCCGTDKRHIGCAAHHVINRFGQGWNEEVIAS
>NZ_CP045410|371527:401188|392016_392202_-|WP_152498154.1|DBSCAN-SWA
MPSHLTQHDLAFRWRVSRRTLERWRAQGRGPDWLKICGRVLYRRSDVEAFEEAGRRQRDPQ
>NZ_CP045410|371527:401188|388158_388788_-|WP_152495648.1|DBSCAN-SWA
MPIETWTLYVLTVLALMSTPGPSQLLMLTNSGVYGFQRSLWTAAGDLSANALQMLAAGLGLATIIAASATALTVIKWAGVAYLIWLGIRMIRRAKPDESAELSEQKKASLRTLWLQGFLTSAANPKAVVFFAALFPQFITSDAAFWPQFLILSATYIVMDGLFLSAYGLGSSWIVKRFKGSARVWIERIGGGFMIGAALLLGLKSISRQ
>NZ_CP045410|371527:401188|379908_380520_-|WP_152495640.1|DBSCAN-SWA
MPRPSHREKLLDIAQDSILAKGFDATSIDEIVAAADITRGGFFYHFADKNALALALIERHVIFEDQIFDDLFARAAELSDDPLHRALIGLKLLAELLEDMEAGHPGCIVATAAYQERLFNQAVRDANRRAVLGWRRRFREMFDEIAKVYPPQEEVDLNALADFVSTVVEGGIVIAKSLGEPKMTAGQVMLLRQYIRLLFLPRS
>NZ_CP045410|371527:401188|371527_372547_-|WP_152495634.1|transposase|DBSCAN-SWA
MTVKTVGLDLAKDVFQVHGISENGRVIFNKAIKRAKLLSFFETLAACTVGMEACGSSHHWGRQLRKLGHDVKLMPAGYVKPYVKRGKNDAVDAEAICEAVRRPTMRFVEIKTEEQQAILSIHRTRDLAVRQRTQMANMIRSLLREFGHILPIGIEAVTAFAKRHLNGDHPDMPEIANSMLGIQCYQFIGLNERIDGYSKMIEQHALLNADARRLMRMPGIGPITASAIVATIGDAHQFRTGRDLAAWLGLTPLNKSSGGKERLGKITKKGDRYIRKLLVVSMTSRAVMAKRSPEKVDLWTAKTIADKPFRLATTAMANKAARIIWAMLTKKQEYRQPAF
>NZ_CP045410|371527:401188|377732_379163_-|WP_152495639.1|integrase|DBSCAN-SWA
MPDLSNSQTIETLKSREAPHWQILEYCRHIGLQKKTPVSGYWVARIRNKSLGYYQKRLIPWEAQTDNYDEALEAARRWFSQPKIAKQAADPFPIGSKQDLNYCPWGNVFTVGHAMRDYVEWKRISATKSHFDSMVSRINHHILPRLGHMPLDELTGRHIVQFSLDVLETPPKRGKQKAIERLPLIELDPDDLRKRKKTLNGLIGVLRLAVQLAWENGETDSERSWRCIRRVPLADTPRTIFLTREECSRLLDCCRPDLREIVQGALYTGCRITELAKLRVRDVAAHVFGLYVEPLKSRKPRYVFLPDEGMAFFLDLCAGRLPDDLVFRRQSGQSWQNGHKHLFREAVIQAELPTAFVFHGLRHTYASQLVQAGTPLIVVAQQLGHANTDTVSRTYGHLAPQIREVQVRTHFAALDRHFVERAHLQKTELEALSRSLQGTDWRAYGRIDPMDSWPRSNFAMTEPEVVKILKDAERPN
>NZ_CP045410|371527:401188|385391_386642_-|WP_172978773.1|DBSCAN-SWA
MATRADRRATAIRQCPVEELIPYANNARTHSDAQIALIAGSIREFGFNNPVLVDGANGIIAGHGRLEAARRLRLKEVPVIELAHLSEAQKRAYILADNRLAERAGWDRELLALELGDLSELGVDLSDLGFEGAELDALLDNGSADPREEETPVPPANPVSRPGDLWRLGNHRLLCGDATNRDDVSRLLGDVRPHLMATDPPFGVNYDPAWRNETGATRTKRTGRVANDDRADWREAWALFPGDVAYVWHGALHAGTVAESLVASGFEIRSQIIWAKERLVLSRGHYHWQHEPAWYCVRGKGHWSGDRKQSTLWEIPNRDQDAQTIHGTQKPVECMRRPMLNNSSPGQAVYEPFSGSGTSLIAAETCGRVCHAMELDPAYVDVAVRRWESFTGETATLDEDGRSFEEVASRRQVEAA
>NZ_CP045410|371527:401188|399519_399783_-|WP_152495658.1|DBSCAN-SWA
MTIPLPKSGSQTHYVFAVAYLALGCLLTAACVTHDPATAVTGGRGADLTRLIGVMLDEVGLAATLLAGWLLALIGSAFHILMARGVI
>NZ_CP045410|371527:401188|374441_374708_+|WP_152495636.1|DBSCAN-SWA
MIELHGWSTIREAFREQDESDEVLSSAISQIEQAISKLSDFNLAAKLMSQNGINSLLINGNFNHRDMVTCSPWSPHLSVSSVQGLVLF
>NZ_CP045410|371527:401188|376477_376636_-|WP_172978772.1|DBSCAN-SWA
MTKARLEEAERILAAYAAKYGLSENARDYFAKWGTAKERLLMGTEQTSESQN
>NZ_CP045410|371527:401188|381999_382578_+|WP_152495642.1|DBSCAN-SWA
MITLEPPFRFATPSDSAELADLVNFAGEGLPLYIWKSLAANGQDPWDIGKARQAEKAREGQIAVVDLGQGAVACLTGYVIGNEPTAIGEDFPALFRPLQELENQALDSWYVNVLACYPTHRGKGIGSQLLDLADEIGRSEGVRQMSIIVASNNTGARRLYERHGYVETATAPCIKENWATRTEKWVLLLKRL
>NZ_CP045410|371527:401188|388986_392013_-|WP_152495649.1|DBSCAN-SWA
MRVERTLPAPQTNENSNRAANGGPVGAGHITFGLAAEQLLSQGFEPLPIRMGGKAPAVTRWSSVEIDDAKVAQWCRTHANCGVGLRTGRLIGLDIDCLDAHEAHRVQSLAEARFGTTLVRVGQWPKRLLLYRADHAFPKLKTGSVEILGAGQQFVAFGIHSGTGKPYYWPMGETVLDCKIDDLPLITEDDARAFLAEVHPGPQWGARRSKSSAPSAATGPVEVIRRNGRVVDGRDAWLSQIAFHSVHDLLDRGETPVPVTLASLVWERFANTTDLDRPRSSTGRAFDVADATRKVADKLRLLDEGRLPGREISTPTPDYTPAALSVEEGRTRLQELLSAYCQQVLAWHRIHEEEPPSLGVRATVGLGKSRAARAAIRDMKKALRNEGLPHRILVFTPSHALAEETACAGRDLGIDAAVLRGYERKDPATGDPMCRDIEMVRAVLASGLSVQDHACRSREGNQCRYFDSCLKQQNRKDVAAADVVVAPYDTLFSGLAFSEDNVGLILVDEGCWQRAVETCSDLFVEDLLDEPFHRMGENRVGGSPVAAMADLSAFRQAAARALRQGQKGISLIRSLRAEGLTYEDCQHAAKLEEWRKTDAAFMPGLDRAHRAKALRTAKANQRIDLLSRLWRALADLLRHGEQPGQSLQVRPAGSDGRQAIEMRRVKRVHDSLRGKPVLHLDATLRQSLAEAILPPMEIECIDVSAPHMHLRQVTGSFGKSMICPLPGLPAEELKRRGNRLRECVDYVRWHALRVFPRDVLVVTYQAIEDAFSDIPNVVTAHFNAVAGLDIYKDVVMLISIGRPLPPSQETEDLARVLFGGVEESGYVSDRVGLHMRTGRTCGLAAVRHKDGTAETLRAAICDDEMVQAIGRGRGVNRSAANPLEVHILADVALPLVYDRLTTWDAEKPYLFQQMLLASVAVDSPADAAALHPELFGNSNEAKLAFKRSAFKGQNPMYSSYREMTLKSAAYRRDGRGRCWQRAWWGAGDEAQVRCLLEIALGKLSGWRI
>NZ_CP045410|371527:401188|372911_374051_-|WP_152495635.1|DBSCAN-SWA
MSRRIQITRRSFGLGAIALGVSACGSSGPGTVRSTIPSGLPADLRPVPNVNYDAWVASFRERAATKGISQSTLASAFRNTGYLPGVVTRDRNQTEFKRSLEDYLAIAASEERVQKGRAAFARHRGTLMALEDRYGVDAYIIAAIWGLESFYGERRGEVPVISATSTLAFDGRRGQFFEQQLIAALRIVQNGDIPASRMTGSWAGAMGHTQFIPTSYLQFAVDYTGDGRRDIWSDDPSDALASAAAYLQRNGWQRGVRWGSETSNGSLQPQPGGPRFATTRNFSVIKRYNNSDAYAIGVGHLSDRIRGGGPLRTAFPPDANGLTKADRVRLQKRLTARGFDTQGADGVIGRDTEAAIRAYQESRGLPVTGTPSQGLLQSL

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
361778:361808	attL	NA	NA	NA	NA
WP_152495634.1|371527_372547_-|transposase	IS110 family transposase	NA	NA	NA	NA
WP_152495635.1|372911_374051_-	lytic murein transglycosylase	NA	NA	NA	NA
WP_152495636.1|374441_374708_+	hypothetical protein	NA	NA	NA	NA
WP_152495637.1|374672_375781_-|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	5.3e-53	43.5
WP_172978772.1|376477_376636_-	hypothetical protein	NA	NA	NA	NA
WP_152498152.1|376740_377736_+|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_152495639.1|377732_379163_-|integrase	tyrosine-type recombinase/integrase	A0A1R3Y6Z3	Salmonella_virus	2.2e-11	26.9
WP_152495640.1|379908_380520_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_152495641.1|380702_381674_+	homocysteine S-methyltransferase family protein	NA	NA	NA	NA
WP_152495642.1|381999_382578_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_152495643.1|382839_383298_+	DUF2267 domain-containing protein	NA	NA	NA	NA
WP_152495644.1|383564_383864_-	hypothetical protein	NA	NA	NA	NA
WP_152495645.1|384039_384738_-	recombinase family protein	A0A0F7L6S1	uncultured_marine_virus	1.1e-35	45.2
WP_152495646.1|384812_385349_-|terminase	phage terminase small subunit P27 family	Q6DMU4	Streptococcus_phage	7.3e-24	40.5
WP_172978773.1|385391_386642_-	site-specific DNA-methyltransferase	A0A0A8ILE7	Aurantimonas_phage	1.0e-129	55.9
WP_152495647.1|387002_387956_+	hypothetical protein	NA	NA	NA	NA
WP_152495648.1|388158_388788_-	LysE family transporter	NA	NA	NA	NA
WP_152495649.1|388986_392013_-	bifunctional DNA primase/polymerase	I6NPA6	Burkholderia_phage	1.9e-20	31.9
WP_152498154.1|392016_392202_-	DNA-binding protein	NA	NA	NA	NA
WP_152495650.1|392210_392390_-	hypothetical protein	NA	NA	NA	NA
WP_152495651.1|392455_393106_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_152495652.1|393279_393495_-	hypothetical protein	NA	NA	NA	NA
WP_152495653.1|393587_395786_-	hypothetical protein	NA	NA	NA	NA
WP_152495654.1|396105_396561_+	DUF2924 domain-containing protein	K4I3X1	Acidithiobacillus_phage	1.7e-21	43.1
WP_152495655.1|396557_397868_+	recombinase family protein	K4ICM1	Acidithiobacillus_phage	8.4e-122	52.7
WP_152495656.1|397864_398248_+	hypothetical protein	NA	NA	NA	NA
WP_152495657.1|398328_398724_+	hypothetical protein	NA	NA	NA	NA
WP_152495658.1|399519_399783_-	hypothetical protein	NA	NA	NA	NA
WP_152495659.1|400555_401188_+|integrase	tyrosine-type recombinase/integrase	A0A0A8WF93	Clostridium_phage	3.0e-08	27.7
407464:407494	attR	NA	NA	NA	NA

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NZ_CP045410|1970517:1983370|DBSCAN-SWA
ATTATCCCAAGGCGCCCATCTGGGCCGTGGCCAACCGTCCGCCATACGCCTCCTGAAGGTTGGCGCGGGTAAAGGCATCGGCCACCGACCCTTCGGCAATCTTGCTGGTGCTGATGACGAAGACGCGGTCGAAATACTCGGTGACCGTCGACAGGTCGTGATGCACCGCGACCACCGTCTTGCCCAGTCCGCGCAGGTCCTTCAGCACGGAGATTATCGCCGTCTCGGTCGCGGCATCGACCCCCGCGAAAGGCTCGTCCAGAAGATAGAGGTCCGCATCCTGCGCCAGGGCTCGCGCCAGGAACACCCGCTGTTGCTGACCGCCGGACAATTGCCCGATCTGCCTGTCCGCAAAGCCGTCCATACCCACGCGCTCGAGACAGTGCAGCGCGGCTTGCATGTGCTTGGTTCTTATCCGCCCCAGCAGGCCGAGGTCCCGGTATTGGCCCATCAACACCACGTCCAGAACCCGCGCGGGGAAATCCCAGTCCACGCTGGCCCGTTGCGGCACATAGGCGATCCGGGCCCGCATCTTTTCGAGCGCCTCGCCCCACGCCGTGACCCGCCCGGAGACTGGCTTGACGATCCCCAGCGCGGCCTTCAGCATCGTCGACTTGCCCGCGCCGTTCGGCCCGATGATGGCCGTCATCGCGCCTTGCTGAAACGTCGCATCCAGGGAAAACACGGCAGGCTTTTCCCCGTAGGACACGGTCAGGCCACGCACCGCGAGCGGGCTCGCCGCCAGCGCATCGCGATCCTCGCGCTCGGCCTCGGTCGTTACCACCTTCACGGTCACCGCCTCAGCTCCCTTCCGCCAGCTTGCCCTGCATGCCGCGGTCTGGCACCTCGCCGCCCAGCGCCTGGGCAATGGTCGTGACATTGTGGTCGATCATCCCGATATAGGTGCCGGTATACGTGCCCGGCGCACCCATCGCGTCGGAATAGAGTTCACCCCCGATCTTCACCTCGTGGCCCTGCGCCGCCGCCCCTTCGATCAGGGCGCGCACGTTGCGGTCGCTGACGGAGGTTTCGACAAACACCGCCCCGATGCCGCGTTCCACCAGCATATCGGCCAATGTCCTGATCCGGTTCAGCCCGGCCTCCGACTCCGTGGAGATGCCCTGAATCCCGACGACTTCGAAATCATAGGCCTCGCCGAAATAGCCAAAGGCGTCATGCGCGCTCAACAGGACGCGAGCAGAAGACGGCACCGTCTCCAGCACGCGGTGCGCATAGGACGCCAGGGCGTCCAGTTCCTTCAGGTAGGCGGCTGCGTTCGCCGCGAATTGATCGGCGTGATCCGGCGCCACATCGCTCAACGCGTCACGGACGCCATTCACCACGTAAGCCCAAAGTTCGGGCACCATCCAGACATGCGGGTCGAACTTGTCGGCGTAATCCTCATGCGCGATCCGCCGGTCCCGCGGCACGCTTTCGCCCACCGGCACCGCGGTCCCGCGTTCGTCCAGCTTCAGCAGGAACTCCTCCATTTGCGCCTCGAGGTACAACCCGTGCCAAAGAACCACGTCGGCGCGCAGGGCGGCCTGGATGTCGGTTCGGGTCTGGCGATAGGAATGCGGATCGATACCCGGACCCATCAGCGCCGTGACCTCCACGAGGTCGCCTCCGACACGCCGCGCGGCGTCGGCGATCATCCCGGTTGTGGCAACCACTGACAGAGCCGCGCCTTGCGCCCGCAGCGGCGTCCCGGCCAGAGCAGCGGCAGACAGCGAGGTGATCAACAGATTTCGGCGAGACAATTGCATGATTTCAGGACTCTCTTTGAGGCGCTTAAAATGATTATGCAAGTCATTCTCAAAAAGTCAACCCGGTGCGGTGCCCCAATCCGCCGCGACGGGAACGGAAAATAGCGAAAACGCGGACTGTAAGTGTCACGTCTTGCGCTGTAATAGCGGATCGGCAAGATTTCGGTTTCGACTGAACGATCCTTAATGGTGAAAATAAGGTAAGGCGACATGATCACACCAGTGCTTTTGTGCGGCGGGTCCGGGACACGGCTTTGGCCGCTCAGCCGGAAATCCTACCCGAAACAATTTGCGCCGGTCTGGGATCAGGGCACGCTTTTCCAGCGGACAGCGCAGCGTCTGTCGGGCCGGGATTACACCGCGCCCCTGGTGATCACCGCATCCGATTTTCGCTTCATTGTCGCGGAGCAGTTGCAGGAGGTCGGCATAGATCCCGGCACGATCATGCTGGAACCCGATGGGCGCAACACCGTTCCGGCCATCCTTGCCGCCGCGCTTTACCTGTCGAAACAGGACCCGGACGCCCTGATGCTCGTCGCGCCGTGCGATCACGCGTTCAACGACGCGGAGGCCTTTCGCGCCACCGTGCAAGCCGGCGTGCCTGCCGCGCTCAAGGGCGATCTGGTCACGTTCGGCATCACCCCCAGCTATGCCGAAACCGGCTACGGCTATCTCCAGCTTGCCGCAGAGCCGGACGGCACCACCCCCGTGGCCCTTTCGCGGTTCGTCGAAAAACCTGATGCCGCGCGGGCAGCCGAGATGGTGGCCGATGGACGTCACCTGTGGAACGGCGGGATCTTCCTGTTCCGCGCCAGCGATATCCTGACAGCCTTCGACGCCAGTGCGCCGACTCTCGTGGAACCCGTTCGCGCGGCACTGGAGGGCGCACAGCCCGACCTTGGCTTCCTTCGCCTCGCGCCCGAGCCCTGGGCGCGCGCCGAGGACATCTCGATCGACTTCGCTGTCATGGAACGCTCGAAGAACCTGTCGGTGGTTCCGCTGTCGCACGGCTGGTCGGACCTTGGCGGCTGGGACGCGATATGGCGCGAAAGCCCACAGGATGAAAAAGGTGTCGCCACCAGTGGCCCCGCCACGGCATTGGAGTGCGAAAACACGCTTCTGCGTTCTGAATCCGACAGGCTCGAACTGGTCGGCATCGGTCTCAAGGATATCGTGGCCGTCGCCATGCCCGATGCCGTCCTGGTGGCACACGCCTCGCAGGCTCAAAGTGTGAAGAAAGCCGTCGACGCGCTGAAGAAAAAGTCCGCCGCGCAAGCAACGCAGTTTCCCAAGGACCACCGCCCTTGGGGCTGGTTCGAAAGCCTCGCGCGTGGCAAGCGATTCCAGGTCAAGCGCATCCACGTGCATCCCGGCGCCGCGCTCAGCCTGCAAAGCCACAACCACCGCTCCGAACACTGGATCGTGGTCCAGGGCACCGCCAAGGTGACGATCGACGGCAAGGAAGAGCTGATCACGGAAAACCAGTCGGTCTACATCCCGCTTGGCGCGGTCCACCGGATGGAAAACCCCGGCAAGGTGCCAATGGTCCTGATCGAGGTTCAAACCGGCAGCTACCTGGGCGAAGATGACATCATCCGCTACGAGGACGTATATGCGCGGTCATAGGCCCGTAGCGGCCGTCTTTACCGCTGCAAAGGTGCCATCGTCGCGTCGTGACATCGTCCCGATCGGCTGATACTACCGGAACGATTTCAAGCGGAGGCGCGCCTGTGAACATCACCGAAACTGCCTTGCCGGGCGTATTGCTGCTCGAGCCGGCCCGCTTCGGCGACTCGCGCGGCTTCTTCAGTGAAAGCTGGAGTCGCAAGACGCTGGCGGCCCATGGAATCGAAATCGACTTCGTTCAGGACAACCATTCGCTGTCAGAGCAGGCCGACACGGTGCGCGGTCTGCATTTTCAGTCACCCCCCCACGCCCAAGCCAAACTGGTGCGCTGCGGGCGCGGGCGGCTGTTCGATGTGGTCGTCGACATCCGCAAGGGCAGCCCCACCTACGGGCAATGGCTGGGCTACGACCTCAGCTTCGAGAACGGCCTGCAGCTTCTGATCCCCGAAGGCTTCCTGCACGGGTTCGCCACGCGCGAACCCGCCACCGAAATCGTCTACAAATGCGGCGATTACTATGCGCCCGAATGCGATGGCGCGGTGTTCTTCGATGATCCCGATATCGGCATCGACTGGAACCTTTCCGGCGACGCGGTTCTGTCGGAAAAGGACGCGGCCGCGCCGCGCCTGGCCGAGTTCGACAGCCCCTTCGTCTGGACGGGTGCGCCATGAAGCTGCTCGTGACCGGCGGCGCCGGATTCATAGGATCGGCCGTGGTGCGCCTGGCCATCGCGCGCGGCCACGCGGTGGTGAACCTCGATGCCCTGACCTATGCCGCCTGCCTGGACAACGTGGCCCCCGTGGCCTCCGATCCCGGATACAGTTTCGTCAAGGCCGACATCCGCGACCGGCCCGCGCTCGATGCCGCCCTGGCCGAACACCAGCCCGACGCGATCATGCACCTGGCCGCGGAATCCCATGTCGACCGCTCGATCGACGGACCGGGTGCGTTCATCGACACCAATGTCATGGGCACCTACACCCTGCTCGAAGCGTCTCGCGACTATTGGGAGGTCCGGGGCCGCCCCGAGACCTTCCGGTTCCATCACATCTCGACCGACGAGGTCTTTGGCTCGCTCGGTCCGACCGGCATGTTCACCGAGACCACGCCCTACGATCCGCGCTCGCCCTACTCGGCCTCCAAGGCGGCCTCGGACCACCTGGTGCGCGCCTGGCACGAAACCTACAGCTTGCCGGTGGTGCTCACCAACTGTTCCAACAATTACGGCCCCTACCACTTCCCGGAAAAGCTGATCCCGGTGATCATCCTCAACGCGCTGGCCGGCAAGCCGCTGCCGATCTACGGCGACGGATCAAACGTGCGCGACTGGCTTTATGTCGAGGATCACGCCGACGCCCTGCTGACCGTGCTGGCGAAAGGCGTCGTTGGCGAAAGCTACAACATCGGTGGCGAGAACGAGCGCACGAATCTCGAACTGGTCCAGTCTCTCTGCGCGATCCTCGACGACAAGCGCCCGAAGGCCAGCGGCTCCTACGCGGATCAGATCACCTTCGTCACCGACCGCCCCGGCCACGACGCCCGCTATGCCATCGACCCCACGCGCATCCGGCAGGAACTGGGCTGGCGCCCGTCCGTCACCGTCGAAGAAGGGCTGGAGCGGACCGTGCAGTGGTATCTGGACAACGAGGCGTGGTGGCGCGCATTGCAGACCCGCGACGGCGTCGGGCAACGTCTTGGCGCAGGGGGCGTGCGATAGGCCCCGGGACAAACCGTTTGGCAGAACCGCGCGTCAGGGACTATCGACGCGGGGGCCCGTCAGCCGGGTCAACGCAATTGGAGCACGACGGATGAGCACACTTGTTTTCGGCAGCTCGGGCCAGGTGGCAACCGAACTGCGTCTCTCGGCACCCGACGCCAGGTTTCTGGGACGCGACAGCGCAGACCTGGCCGACCCCGCCGCCTGCGCTGCCGCGATCGCCGCGCACCGTCCCGACCTTGTGATCAACGCCGCTGCCTACACCGCCGTCGACCGCGCCGAGGAGGAAGAGGCGCTGGCCCACGTCATCAACGCCGACGCCCCCGGCGCGATGGCGCGCGCGGCGGCGGAGCTGGGCGTGCCCTTCGTTCATATTTCCACCGATTACGTCTTTGCCGGCACCGGCACCGGCACCCGCCCCTGGGCACCCTCCGACGCGACCGCGCCGCAAAACGCCTATGGCCGCACCAAGCTGGCGGGCGAAGAGGCGGTGCGGGCCGCCGGCGGCGTCCACGCCATCCTGCGCACCTCCTGGGTGGTGTCGGCGCACGGGGCGAATTTCGTCAAGACCATGCTGCGCCTCGGGGCCGAGCGGGACGCGCTGACCATCGTCGCCGATCAGGTGGGCGGGCCGACGCCCGCGCGCGACATCGCGACGGCCTGCCTGCGTATCGGCGACGCGCTGCGCCACGATCCTGCGCTGTCGGGCTCCTTCCACTTCTCGGGTGCGCCCGATGTCAGCTGGGCCGATTTCGCCCGCGCGATCTTCGACAAGGCCGGGCTGAACTGCGCGGTCACGGACATCCCCACCGCGGACTATCCGACCCCGGCGGCCCGGCCATTGAACTCGCGGCTGGATTGCACCAGAACCGAAAGCGTATTCGGCCTGTCCCGCCCCGACTGGCGCGACGGCCTCGACGACATTCTGAAGGCCCTGAAGGAGGCGCAAGATGCTTGATCTGACGACGCACCTGCGTGACCGCGGGACCGGCCCGCGCCCGGAGGGATGCGCATGACACGCAAGGGCATCATCCTCGCCGGCGGCTCCGGCACGCGGCTCTACCCGATCACGATGGGCGTCTCGAAACAGCTTCTGCCGATCTATGACAAGCCGATGATCTATTACCCGCTCTCGGTGCTCATGCTGGCCGGTATCCGCGAGATTGCCATCATTACCACGCCCCAGGATCAGGCCCAGTTCATCCGCACGCTGGGGGATGGCGCCCAGTGGGGCCTCAGCCTGACCTATATCGAGCAACCCTCGCCCGACGGGCTGGCCCAGGCCTATATCCTGGCCAGGGATTTCCTCGCCGGCGCCCCGTCTGCGATGGTGTTGGGCGACAACATCTTCTTCGGCCACGGCCTGCCGCAACAACTGGCCGAGGCCAGCGCGATCGAAACCGGCGGCACCGTGTTCGGCTACCGCGTCGCAGACCCCGAGCGGTATGGCGTGGTCGATTTTGCCCCCGACGGCACGGTGAAGACGATCATCGAAAAGCCCGCCAGACCGCCCTCGAACTACGCGGTCACCGGACTTTACTTCCTCGACGGCACCGCCCCCGAACGGGCCGCCAGGGTGCAGCCGTCCGAGCGTGGCGAGCTCGAGATCACGTCGCTTCTGGACATGTACCTCGCCGACGGGCAACTGACCGTCCAGCAAATGGGCCGCGGCTATGCCTGGCTCGATACCGGAACCCACGGCTCGCTTCTCGATGCGGGCAACTTCGTGCGTACGCTGTCGGAACGCCAGGGCCAGCAGGTCGGCTGCCCCGAGGAGATCGCATATGAGCAGGGTTGGATCAACGCCGAGGACCTGGCCCGGCGCGCGCGGCTGTTCGAGAAGACCAATTACGGGGCCTATCTGAAGGGGCTTCTCTGAGCCTCGGAACAATGACCATTCCGGAGGTTGGCGTGTCGCGGGCACCTGGTTTTCAAGGTCTCCTTTGCGGGACGAAGCCGCCGTTCACGACGGAGGCGAGCGTCAGCCCCAGCGCGGAGTCAGGCCGCAGGCCACGCGCCATCGCCGTGCCGCCCCCACGGCCCGGCGATTGGGTGACGTTCGGTGCATCGCTCAATCATGTTTTGGATTTGGCTTGGATAAAGCGCTGCCGACCCCCCGTCGGATCGCCGCGCCGCGGCCCGCCAATGGCGCTCGATACCAGGGTCTCGCAACGACCCATGAACTGCCATCTCCAAGTGTAGTGACCCCCCGCCACAGAACCCGCCTCACGCGCCTGGTGTAACCGCCATGAAAAAGCCCCCGCCAACAGGGGCGGGGGCAAGGTGAGTGCCATGTGTCAGGCCACAGGCACCGGCGGTGTTCTTGAATGTCCTGGGACTGGCTAGTTGGCGCGGTCGGCCATCTCGGCCCGGATCTGCTGCCGGAACACGTCGATGGACACCGGCTTGCCGTCACGCTTGATGCACCAGTAGGTCCAGCCGTTGCAGCTGGGCGCGCCTTCCAGCGCCGCGCCGACCTGGTGAATCGAGCCTTTGACGTCATCGCCCACCAGCGTGCCATCGGCGCGCAGCTTGGCCTTATGACGTCCGTTCATGCTCAAGAGTTCCTCGCCCGGCCGCAACATGCCCCGCTCGATCAGCTGGCCAAACGGCACCCGCGGCTCGGCGCGCTTGCTGGTGCTGACCTGCAACGCCTCGCGGTCGTATTTGCGCACCGAAGACAGCCGTTTCTCGGCCACTTTGCGATAGGCCGCCTCGCGCTCGATCCCGATGAACTCGCGCCCCAGCATCTTGGCGACCGCGCCCGTTGTGCCGGTGCCGAAAAACGGGTCCAGCACCACATCGCCGGGGTTGGTCGTGCCCAGAAGGACCCGGTGCAGCAGGCTCTCGGGCTTCTGCGTCGGATGCGCCTTGTCGCCTTGCTCGTCCTTCAGCCGCTCGTGCCCGGTACAGATCGGCAGCACCCAGTCGCTGCGCATCTGGATGCCTTCGTTCAGCGATTTCAGCGCCTCGTAGTTGAACGTGTATTTCGCCGCCTCGTCCCGGCTCGCCCAGATCAGCGTCTCATGCGCGTTGGTCAGCCGCTTTCCCCGGAAATTCGGCATCGGGTTGGACTTGCGCCACACCACGTCGTTCAGGATCCAGAAACCCGCGTCCTGCAACGCCGCGCCGACGCGGAAGATGTTGTGATAGGACCCGATCACCCAGATCGCGCCATTGGGCTTCAACAGACGCCGCGCGGCCTTCAGCCAGTCGCGAGTGAAGCGGTCATAGACCTCGAAACTGGCGAACTGATCCCACGCGTCATCGACCGCGTCCACCTGGCTGTTGTCCGGCCGGTGCAGGTCGCCACGCAATTGCAGGTTGTAAGGAGGGTCGGCGAATATCAGGTCGACGCTGCCTTCCGGCAGGCCGTTCATGACCTCGATACAATCTCCACCAAGGACAGTATTCAACGGGAGCGTTTCCACGCCCTTCTTGGTCTTTGTCGTCATCTTTTCTGCCTCTGTCCCGGCGCCTTGTTGTGCGCTCTGGTCGTTGACGCCAAGGATGAGTCAAAGCGGATTCGCGGTCAATTTCTTTTTGAATCAGTCGGTTAGGTTTTTTTCTTGATACAAGATATTGTGGACCGGCTTGAACGAACGTCTATGGTGTGGGGTCGGCCCGAGATTTTGCAAAGCGGCCATGTGGCTTTTCGAGCCATACCCTGCGTTGGTCTCCCAACCATAGCCCGGATACTGTTGCGCCAAATCCCACATGATGCGGTCGCGCCTCACTTTTGCCATAATCGAGGCCGCCGAAATCGACAGGCAAACCGCGTCGCCCCTGATGATCGCGCGCCCCTCGCAGGGCATGTCGCGGGGCAGAAGGTTGCCATCGACCAGCGCCAGGCAGGGCGGGCGCGACAGCCCCGCCAGCGCCCGCGTCATTGCCAGATGCGATGCCCGCAGGATGTTGATCTCGTCGATCTCCTCGACACTGGCATGGGCCACCGAAACCTCGGCCACCTCCAGGATCGCGTCGTGCAGAGCCGCGCGTCGCTTCGCCGTCAGCATCTTGGAGTCGTTCAGCCCCTCGGGTATGCGCCCGGGCGCCAGGATCACCGCCGCCGCCGTCACCGGCCCGGCCAGAGGGCCGCGCCCGACCTCGTCCACCCCGGCCACTTGCAACGCGCCAGCGGCCAGCGCCTCGGTCTCGAACTGAAAATGGGGCCCATGCACGGTTATGCTCATGGGCCCTTCAGTAGTCGCGTTTTCATGGAAGGAAAAGAAGGGAGGCGCACGAAGGATGCTTCGAGCCGCGCGCCTCCCCTCACTGCTCGACCGGTATCCGCGCTCTTATTTGCGGTACTTGTCGCTTCTGCGATCGTTGAACCCGTACCGCTCCAGGCACTGGCTGCCATAGATGACGCCGCGCCGGCCGTGCCCGCGTGTCTCCACAGCGCAGCGATGCGGCAGCGCATTGAACCGCGGATAATTTTTCAGCAGGCAATGCCGCCCATACCCGCGCAGCACGCCGCCCCGGACCCGCACGTCGCGGCGGCACTGCTGCGGCAATGCAAACCGATCGCCATGACGCCCACGATGACCATAGCCGTCATGCCCGCGCCGATGCCCGCGATTGTCGTACCGGTCGTACCCGCGGCGATGCCCGTTGTTGAACCGTGGCCCGTGGCCGCCCTGAAGGCGCGTCACCGCGCGGTCGTCGCGGCGCTGGTCGGCGATGGCCGCGCCGATCAGCCCCAGGGCGACCGCCCCCGCCACCCATTTGGCCACGTCCTTGTCACCGGCCTGCGCCGGCGCGGCTGTCATCCCCGTCACGGCGAGCGCCGCCGCCAGGATCAGCGATATGAATGTCCGATGTGTCATGTCAGGTCCTTTCTCTGCTTGAGCCTTGATCGGTCCCCACCCCGGTCATGACGTCACCGTGTCGGCCCGGGTCAGGCGATGCATCAAGGATGGGTCCAGCCCGCCGAGACAGGCAATAACGGCCACCTGCTATCCGATAACACGGCGCAAAAGGCCGTTTCCCGCCAACCCGATATTGAATAGCGGCAGGGATACGCGCATCTTGGCGCCATGAAACGCAAAACCCTTCCCCTCGTCGTGACGCTCGGCCTTGCCACCGCCACGACCGGCGCCGCACAGGCCGCCTGCTATGCCGAGTACAAGGCCAAGCGCGACACCCCGTTCGAGCTCATCTACGAGGTTGCGCAGGTCAGCGGGCCCTGTACCGTCGCCAACGCCACCGCCCAGCTTGGCGCCCGCCTTGCCGGACAGGGCCTGACCTTGCTCAAGGTCCTGTCGGTCCGCGAAGGCTAGCGCAGGGGGCCAGGGGCACGTGCAGGATCTCGACACTTCCATCACCGACACCCGCCGCTCCGGCAACCGGATCGTGCTCTTTGGCGTCGCGGCCATCGTCACCATTCTCGTCGGTGCCGCCATCCTCCTGGTGCTCACGTTGCCCGACGCCAACGCCTTCAACGACAAGGTGGCGCAGATTTTCGCCGAGAACGACGCGCTCACCTCGGACGCCGAGATCAAGCTCCTGGAAATCCTCGCCCTCTCGGGCACCGCCTTTTCCGAAACCCTGGGCAGCTACCGGATGCTCATCCTCGTGCTGCTGATCTTCGCCACGGCCCTCCTCGTGGCCGCGCTGGTCTTCCTGGTGATGCTCGCCGGCATGAATCGCCGCCTCGCGCAGATCGAACATTCCGGCATCCAGGTCAGTTCGCTGCTCATCAGCCGCGAGGAAAACGCCGTCTACCTTAACAACATGGGGTTCAAGCTGACCGATGCGGCGATGGAAACGCTCGCCGTGCTGGCCGAGGCGCGGATGGACGATGACGTGCTCTCGGGCGCCGAGATCGAGGCGGTGATCTCGGGCCGCGCCGCCGACGACTGCGAGGAAGCCGCGGGCGCGACCCGGATCAAGCGCCTGCGCGACACGCTGGGCAACCAGATGGTGTCGGAACTGCTGGTCAAGAACATCGCGCGGCGCGGCTACATGCTGGCCATCGACAAGAAAGTCATCCGGGTGATCTGACGCCGCCCGCGCCCTAGGACGCGTGTTTCGCTTGGCGCGCTACCAAAAGTTGTGGAACTCACCGCACCCCCACTGCGTTCAAGACCTTAACGTTCAAGAACGAAAAACGTCCAGAGGGGGACAGTCATATGACTACGTGGGTTGAACGGATGGGCCTGAAAACCGATCCGGTGATTTTTTCCGTATCCGCAATCTTCACCCTCGTTTTCGTCCTCGCACTGGTCATTGCCCCCGAACCCATCGGCGACGCCTTCGCTGCCGGGCGCGCTTGGATCGTTTCTCACCTGGGGTGGTTCTTCATCCTCGGCGTCAATCTCTGGCTCGGCTTCCTCGTCTGGACGGCCATGAGCCGCCACGGACATATCCGTCTCGGCCCGCGCGATTCGCGCCCCGATTACACCAACCTGTCTTGGTTCACGATGCTCTTCGCCGGCGGCATCGGCACGGTGCTGATGTTCTGGGGCGTGGCCGAACCCATGAGCCATTTCGCCACCCCGCCCCTGCCCGGGGTCGAGCCCTTCTCCCAGGAGGCCGCGCAAGACGCGATCTCCATCGCCACCTACCACCTCGCCCTGCACACCTGGACGATCTTCGCCCTGCCGGGGCTGGCCTTTGCCTATTTCATCAATCGCTACGACCTGCCCGTGCGGGTCAGTTCGGTCTTCTACCCCCTTCTCAAGGATCGGATCTACGGCCCGTGGGGCAAAGCCATCGACATCGCCGCGGTTCTCGGCACGCTCTTCGGCGTCGCGGTCTCGCTCGGCCTCGGCTCGTCCCAGATCGCCGCCGGGCTCGAGGCCCTGTTCGGCTGGGAAAGCGGCGTCATGCTCAAGGTCGCGATCCTCACGGTGCTGACAGCGGTGGCCGTGGTCTCCATCGTCGCGGGCCTCGACAAGGGCGTGAAGCTGCTGTCGAACATCAATATCGGCATGGCCGTGGGCCTGATGATCTTCGTGCTGATCTGCGGCTCGACGCTCTTTTTGCTGCGCGGCATGGTTGAAACCGTCGGGCTTTACCTCGGCAACCTTCCGCGCCTCGCGTTCTGGAACGACATGCTGGCCGATATTGGCCCCGATTCCGACGGCTGGGGCTGGCAGGGCGGCTGGACCGTCTTCTACTGGGCCTGGACCGTGACGTGGTCCCCTTTCATCGGCCTCTTCGTGGCCCGGATCTCGCGCGGGCGCACGATCCGCGAATTCGTCTTCGGGGTCCTTCTGGCGCCCTCGCTCTTCACCCTGATCTGGTTCTCGATCTTCGGCTGGCAGGCGATGGAAATCGACGGCATCGGCGCCGCCGCGCGCGAGGCGCTGGGCGACCAGGCCGGCGCGCTCAGCGATGCGGTGGCCGAGTCGGTGCCGCTCGCCATGTTCGCCTTCTTCGAAAACTTCCCCTTCGCCGACCTCGTACAGGGTATCGCCGTGCTCGTGGTCGCGATTTTCTTCGCAACCTCTTCGGACTCCGCCTCGCTGGTGGTCGACATGCTCTGCACCGGCTCCCCCGATCCCGGCCCGACCCGCCAGCGCGTGTTCTGGGGCGTCTCCGAAGGGCTGGTGGCCACGATGCTGATCGTCCTCGCCGGCGACGCCGGCCTCACCGCCCTGCAACAGGTCATCACCGTTGTCGGCCTGCCGATCTTCTGCCTGGTGTTCCTGATGATACCCGCCCTGATCCTCGGCCTGCGCAACGAGGAGATCGATCACATCACCATCGGCAAGCGTCCCGGTCTGACGAAGTTCTGA

Protein sequences of DBSCAN-SWA_2

>NZ_CP045410|1970517:1983370|1980926_1981631_+|WP_172978854.1|DBSCAN-SWA
MQDLDTSITDTRRSGNRIVLFGVAAIVTILVGAAILLVLTLPDANAFNDKVAQIFAENDALTSDAEIKLLEILALSGTAFSETLGSYRMLILVLLIFATALLVAALVFLVMLAGMNRRLAQIEHSGIQVSSLLISREENAVYLNNMGFKLTDAAMETLAVLAEARMDDDVLSGAEIEAVISGRAADDCEEAAGATRIKRLRDTLGNQMVSELLVKNIARRGYMLAIDKKVIRVI
>NZ_CP045410|1970517:1983370|1974012_1974579_+|WP_152496738.1|DBSCAN-SWA
MNITETALPGVLLLEPARFGDSRGFFSESWSRKTLAAHGIEIDFVQDNHSLSEQADTVRGLHFQSPPHAQAKLVRCGRGRLFDVVVDIRKGSPTYGQWLGYDLSFENGLQLLIPEGFLHGFATREPATEIVYKCGDYYAPECDGAVFFDDPDIGIDWNLSGDAVLSEKDAAAPRLAEFDSPFVWTGAP
>NZ_CP045410|1970517:1983370|1979173_1979818_-|WP_152496743.1|DBSCAN-SWA
MSITVHGPHFQFETEALAAGALQVAGVDEVGRGPLAGPVTAAAVILAPGRIPEGLNDSKMLTAKRRAALHDAILEVAEVSVAHASVEEIDEINILRASHLAMTRALAGLSRPPCLALVDGNLLPRDMPCEGRAIIRGDAVCLSISAASIMAKVRRDRIMWDLAQQYPGYGWETNAGYGSKSHMAALQNLGPTPHHRRSFKPVHNILYQEKNLTD
>NZ_CP045410|1970517:1983370|1977967_1979080_-|WP_152496742.1|DBSCAN-SWA
MTTKTKKGVETLPLNTVLGGDCIEVMNGLPEGSVDLIFADPPYNLQLRGDLHRPDNSQVDAVDDAWDQFASFEVYDRFTRDWLKAARRLLKPNGAIWVIGSYHNIFRVGAALQDAGFWILNDVVWRKSNPMPNFRGKRLTNAHETLIWASRDEAAKYTFNYEALKSLNEGIQMRSDWVLPICTGHERLKDEQGDKAHPTQKPESLLHRVLLGTTNPGDVVLDPFFGTGTTGAVAKMLGREFIGIEREAAYRKVAEKRLSSVRKYDREALQVSTSKRAEPRVPFGQLIERGMLRPGEELLSMNGRHKAKLRADGTLVGDDVKGSIHQVGAALEGAPSCNGWTYWCIKRDGKPVSIDVFRQQIRAEMADRAN
>NZ_CP045410|1970517:1983370|1971316_1972282_-|WP_152496736.1|DBSCAN-SWA
MQLSRRNLLITSLSAAALAGTPLRAQGAALSVVATTGMIADAARRVGGDLVEVTALMGPGIDPHSYRQTRTDIQAALRADVVLWHGLYLEAQMEEFLLKLDERGTAVPVGESVPRDRRIAHEDYADKFDPHVWMVPELWAYVVNGVRDALSDVAPDHADQFAANAAAYLKELDALASYAHRVLETVPSSARVLLSAHDAFGYFGEAYDFEVVGIQGISTESEAGLNRIRTLADMLVERGIGAVFVETSVSDRNVRALIEGAAAQGHEVKIGGELYSDAMGAPGTYTGTYIGMIDHNVTTIAQALGGEVPDRGMQGKLAEGS
>NZ_CP045410|1970517:1983370|1976637_1977504_+|WP_152496741.1|DBSCAN-SWA
MTRKGIILAGGSGTRLYPITMGVSKQLLPIYDKPMIYYPLSVLMLAGIREIAIITTPQDQAQFIRTLGDGAQWGLSLTYIEQPSPDGLAQAYILARDFLAGAPSAMVLGDNIFFGHGLPQQLAEASAIETGGTVFGYRVADPERYGVVDFAPDGTVKTIIEKPARPPSNYAVTGLYFLDGTAPERAARVQPSERGELEITSLLDMYLADGQLTVQQMGRGYAWLDTGTHGSLLDAGNFVRTLSERQGQQVGCPEEIAYEQGWINAEDLARRARLFEKTNYGAYLKGLL
>NZ_CP045410|1970517:1983370|1970517_1971396_-|WP_152490945.1|DBSCAN-SWA
MSRPLPRRWAARCQTAACRASWRKGAEAVTVKVVTTEAEREDRDALAASPLAVRGLTVSYGEKPAVFSLDATFQQGAMTAIIGPNGAGKSTMLKAALGIVKPVSGRVTAWGEALEKMRARIAYVPQRASVDWDFPARVLDVVLMGQYRDLGLLGRIRTKHMQAALHCLERVGMDGFADRQIGQLSGGQQQRVFLARALAQDADLYLLDEPFAGVDAATETAIISVLKDLRGLGKTVVAVHHDLSTVTEYFDRVFVISTSKIAEGSVADAFTRANLQEAYGGRLATAQMGALG
>NZ_CP045410|1970517:1983370|1980664_1980907_+|WP_152490935.1|DBSCAN-SWA
MKRKTLPLVVTLGLATATTGAAQAACYAEYKAKRDTPFELIYEVAQVSGPCTVANATAQLGARLAGQGLTLLKVLSVREG
>NZ_CP045410|1970517:1983370|1979923_1980454_-|WP_152490936.1|DBSCAN-SWA
MTHRTFISLILAAALAVTGMTAAPAQAGDKDVAKWVAGAVALGLIGAAIADQRRDDRAVTRLQGGHGPRFNNGHRRGYDRYDNRGHRRGHDGYGHRGRHGDRFALPQQCRRDVRVRGGVLRGYGRHCLLKNYPRFNALPHRCAVETRGHGRRGVIYGSQCLERYGFNDRRSDKYRK
>NZ_CP045410|1970517:1983370|1972492_1973908_+|WP_152496737.1|DBSCAN-SWA
MITPVLLCGGSGTRLWPLSRKSYPKQFAPVWDQGTLFQRTAQRLSGRDYTAPLVITASDFRFIVAEQLQEVGIDPGTIMLEPDGRNTVPAILAAALYLSKQDPDALMLVAPCDHAFNDAEAFRATVQAGVPAALKGDLVTFGITPSYAETGYGYLQLAAEPDGTTPVALSRFVEKPDAARAAEMVADGRHLWNGGIFLFRASDILTAFDASAPTLVEPVRAALEGAQPDLGFLRLAPEPWARAEDISIDFAVMERSKNLSVVPLSHGWSDLGGWDAIWRESPQDEKGVATSGPATALECENTLLRSESDRLELVGIGLKDIVAVAMPDAVLVAHASQAQSVKKAVDALKKKSAAQATQFPKDHRPWGWFESLARGKRFQVKRIHVHPGAALSLQSHNHRSEHWIVVQGTAKVTIDGKEELITENQSVYIPLGAVHRMENPGKVPMVLIEVQTGSYLGEDDIIRYEDVYARS
>NZ_CP045410|1970517:1983370|1977556_1977700_-|WP_172978853.1|DBSCAN-SWA
MSDAPNVTQSPGRGGGTAMARGLRPDSALGLTLASVVNGGFVPQRRP
>NZ_CP045410|1970517:1983370|1974575_1975625_+|WP_152496739.1|DBSCAN-SWA
MKLLVTGGAGFIGSAVVRLAIARGHAVVNLDALTYAACLDNVAPVASDPGYSFVKADIRDRPALDAALAEHQPDAIMHLAAESHVDRSIDGPGAFIDTNVMGTYTLLEASRDYWEVRGRPETFRFHHISTDEVFGSLGPTGMFTETTPYDPRSPYSASKAASDHLVRAWHETYSLPVVLTNCSNNYGPYHFPEKLIPVIILNALAGKPLPIYGDGSNVRDWLYVEDHADALLTVLAKGVVGESYNIGGENERTNLELVQSLCAILDDKRPKASGSYADQITFVTDRPGHDARYAIDPTRIRQELGWRPSVTVEEGLERTVQWYLDNEAWWRALQTRDGVGQRLGAGGVR
>NZ_CP045410|1970517:1983370|1981759_1983370_+|WP_152490934.1|DBSCAN-SWA
MTTWVERMGLKTDPVIFSVSAIFTLVFVLALVIAPEPIGDAFAAGRAWIVSHLGWFFILGVNLWLGFLVWTAMSRHGHIRLGPRDSRPDYTNLSWFTMLFAGGIGTVLMFWGVAEPMSHFATPPLPGVEPFSQEAAQDAISIATYHLALHTWTIFALPGLAFAYFINRYDLPVRVSSVFYPLLKDRIYGPWGKAIDIAAVLGTLFGVAVSLGLGSSQIAAGLEALFGWESGVMLKVAILTVLTAVAVVSIVAGLDKGVKLLSNINIGMAVGLMIFVLICGSTLFLLRGMVETVGLYLGNLPRLAFWNDMLADIGPDSDGWGWQGGWTVFYWAWTVTWSPFIGLFVARISRGRTIREFVFGVLLAPSLFTLIWFSIFGWQAMEIDGIGAAAREALGDQAGALSDAVAESVPLAMFAFFENFPFADLVQGIAVLVVAIFFATSSDSASLVVDMLCTGSPDPGPTRQRVFWGVSEGLVATMLIVLAGDAGLTALQQVITVVGLPIFCLVFLMIPALILGLRNEEIDHITIGKRPGLTKF
>NZ_CP045410|1970517:1983370|1975716_1976583_+|WP_152496740.1|DBSCAN-SWA
MSTLVFGSSGQVATELRLSAPDARFLGRDSADLADPAACAAAIAAHRPDLVINAAAYTAVDRAEEEEALAHVINADAPGAMARAAAELGVPFVHISTDYVFAGTGTGTRPWAPSDATAPQNAYGRTKLAGEEAVRAAGGVHAILRTSWVVSAHGANFVKTMLRLGAERDALTIVADQVGGPTPARDIATACLRIGDALRHDPALSGSFHFSGAPDVSWADFARAIFDKAGLNCAVTDIPTADYPTPAARPLNSRLDCTRTESVFGLSRPDWRDGLDDILKALKEAQDA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_152490945.1|1970517_1971396_-	ATP-binding cassette domain-containing protein	M1I1A6	Acanthocystis_turfacea_Chlorella_virus	7.5e-10	31.4
WP_152496736.1|1971316_1972282_-	zinc ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_152496737.1|1972492_1973908_+	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	A0A1V0SH58	Hokovirus	5.2e-53	29.8
WP_152496738.1|1974012_1974579_+	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	4.4e-35	42.9
WP_152496739.1|1974575_1975625_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	2.3e-90	51.4
WP_152496740.1|1975716_1976583_+	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	2.9e-30	37.8
WP_152496741.1|1976637_1977504_+	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	1.2e-87	56.3
WP_172978853.1|1977556_1977700_-	hypothetical protein	NA	NA	NA	NA
WP_152496742.1|1977967_1979080_-	site-specific DNA-methyltransferase	A0A249XUJ2	Enterococcus_phage	2.9e-30	31.4
WP_152496743.1|1979173_1979818_-	ribonuclease HII	G9E3X7	Emiliania_huxleyi_virus	2.6e-23	40.1
WP_152490936.1|1979923_1980454_-	hypothetical protein	NA	NA	NA	NA
WP_152490935.1|1980664_1980907_+	hypothetical protein	NA	NA	NA	NA
WP_172978854.1|1980926_1981631_+	hypothetical protein	NA	NA	NA	NA
WP_152490934.1|1981759_1983370_+	BCCT family transporter	A0A2I7QNT1	Vibrio_phage	2.2e-15	25.3