CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP045480	Amycolatopsis sp. YIM 10 chromosome, complete genome	10 crisprs	cas3,csa3,WYL,casR,DEDDh,cas4,RT,DinG	0	5	1	0
NZ_CP045481	Amycolatopsis sp. YIM 10 plasmid pAmyYIM10, complete sequence	0 crisprs	NA	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP045480_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045480_1

722724-722803

Orphan

Consensus_repeat	Method
CGCGACTGCGGGTAGCTCTGCTC	CRISPRCasFinder

1 spacers

WYL

The CRISPR arrays of NZ_CP045480_1

>merge|NZ_CP045480|1|722724-722803|CRISPRCasFinder
CGCGACTGCGGGTAGCTCTGCTCCGCCGGGCGGGGCGGGTAGTCGGACGCGGGTGTCCGGGACTGCGGGTAGCTCTGCTC

>NZ_CP045480|1|1|722724-722803|CRISPRCasFinder
CGCGACTGCGGGTAGCTCTGCTC	CGCCGGGCGGGGCGGGTAGTCGGACGCGGGTGTC
CGGGACTGCGGGTAGCTCTGCTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045480.1\|WP_153028983.1\|731155_732598_+\|NCS2-family-permease	unknown	unknown	gnl\|CDD\|225161
NZ_CP045480.1\|WP_153028978.1\|724716_727479_+\|molecular-chaperone-Hsp90	unknown	unknown	gnl\|CDD\|223403
NZ_CP045480.1\|WP_153028980.1\|728622_729807_-\|NAD(P)-binding-protein	unknown	unknown	gnl\|CDD\|223727
NZ_CP045480.1\|WP_153028973.1\|718343_718976_-\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|375982
NZ_CP045480.1\|WP_153028970.1\|714675_715446_-\|PhzF-family-phenazine-biosynthesis-isomerase	unknown	unknown	gnl\|CDD\|223461
NZ_CP045480.1\|WP_153036767.1\|733091_734432_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340863
NZ_CP045480.1\|WP_153028984.1\|732642_733074_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_CP045480.1\|WP_153036765.1\|720916_722674_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340863
NZ_CP045480.1\|WP_153028969.1\|714274_714649_-\|YccF-domain-containing-protein	unknown	unknown	gnl\|CDD\|236975
NZ_CP045480.1\|WP_153028979.1\|727540_728626_+\|IS630-family-transposase	unknown	unknown	gnl\|CDD\|315923
NZ_CP045480.1\|WP_153036766.1\|723139_723880_-\|glutaminyl-peptide-cyclotransferase	unknown	unknown	gnl\|CDD\|368283
NZ_CP045480.1\|WP_153028977.1\|723941_724733_+\|DUF3027-domain-containing-protein	unknown	unknown	gnl\|CDD\|378605
NZ_CP045480.1\|WP_153028976.1\|720408_720906_-\|DUF2771-family-protein	unknown	unknown	gnl\|CDD\|378520
NZ_CP045480.1\|WP_153028975.1\|719629_719860_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045480.1\|WP_153028974.1\|719031_719649_+\|HAD-hydrolase-like-protein	unknown	unknown	gnl\|CDD\|223620
NZ_CP045480.1\|WP_153036764.1\|720025_720412_+\|cold-shock-protein	unknown	unknown	gnl\|CDD\|224197
NZ_CP045480.1\|WP_153028982.1\|730814_731129_-\|DUF2530-domain-containing-protein	unknown	unknown	gnl\|CDD\|378488
NZ_CP045480.1\|WP_153028972.1\|717368_718331_-\|R2-like-ligand-binding-oxidase	unknown	unknown	gnl\|CDD\|236242
NZ_CP045480.1\|WP_153028981.1\|729838_730876_+\|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|225253
NZ_CP045480.1\|WP_153028971.1\|715529_717173_+\|AMP-binding-protein	unknown	unknown	gnl\|CDD\|236236

Protein	Function_ID	Function_description	E-value
NZ_CP045480.1\|WP_153028983.1\|731155_732598_+\|NCS2-family-permease	gnl\|CDD\|225161	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism].	1.6475e-120
NZ_CP045480.1\|WP_153028978.1\|724716_727479_+\|molecular-chaperone-Hsp90	gnl\|CDD\|223403	COG0326, HtpG, Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones].	3.56855e-06
NZ_CP045480.1\|WP_153028980.1\|728622_729807_-\|NAD(P)-binding-protein	gnl\|CDD\|223727	COG0654, UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion].	1.93436e-24
NZ_CP045480.1\|WP_153028973.1\|718343_718976_-\|TetR-family-transcriptional-regulator	gnl\|CDD\|375982	pfam18556, TetR_C_35, Bacterial Tetracyclin repressor, C-terminal domain. This is the C-terminal tetracyclin repressor domain found in bacteria. Family members include TetR family transcriptional regulators Rv3249c and Rv1816 found in Mycobacterium tuberculosis. Palmitic acid (a fatty acid) and isopropyl laurate (a fatty acid ester), were identified as binding ligands to Rv3249c and Rv1816 respectively. Similar to other TetR family regulators, these proteins are alpha-helical dimeric proteins consisting of a smaller N-terminal DNA-binding domain and a larger C-terminal regulatory domain.	5.55291e-26
NZ_CP045480.1\|WP_153028970.1\|714675_715446_-\|PhzF-family-phenazine-biosynthesis-isomerase	gnl\|CDD\|223461	COG0384, COG0384, Predicted epimerase, PhzC/PhzF homolog [General function prediction only].	4.35943e-65
NZ_CP045480.1\|WP_153036767.1\|733091_734432_+\|MFS-transporter	gnl\|CDD\|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.06458e-70
NZ_CP045480.1\|WP_153028984.1\|732642_733074_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	3.8952e-19
NZ_CP045480.1\|WP_153036765.1\|720916_722674_-\|MFS-transporter	gnl\|CDD\|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	7.79273e-25
NZ_CP045480.1\|WP_153028969.1\|714274_714649_-\|YccF-domain-containing-protein	gnl\|CDD\|236975	PRK11770, PRK11770, YccF domain-containing protein.	3.62223e-56
NZ_CP045480.1\|WP_153028979.1\|727540_728626_+\|IS630-family-transposase	gnl\|CDD\|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	4.14079e-16
NZ_CP045480.1\|WP_153036766.1\|723139_723880_-\|glutaminyl-peptide-cyclotransferase	gnl\|CDD\|368283	pfam05096, Glu_cyclase_2, Glutamine cyclotransferase. This family of enzymes EC:2.3.2.5 catalyze the cyclization of free L-glutamine and N-terminal glutaminyl residues in proteins to pyroglutamate (5-oxoproline) and pyroglutamyl residues respectively. This family includes plant and bacterial enzymes and seems unrelated to the mammalian enzymes.	4.13921e-110
NZ_CP045480.1\|WP_153028977.1\|723941_724733_+\|DUF3027-domain-containing-protein	gnl\|CDD\|378605	pfam11228, DUF3027, Protein of unknown function (DUF3027). This family of proteins with unknown function appears to be restricted to Actinobacteria.	1.47253e-108
NZ_CP045480.1\|WP_153028976.1\|720408_720906_-\|DUF2771-family-protein	gnl\|CDD\|378520	pfam10969, DUF2771, Protein of unknown function (DUF2771). This bacterial family of proteins has no known function.	4.01987e-21
NZ_CP045480.1\|WP_153028974.1\|719031_719649_+\|HAD-hydrolase-like-protein	gnl\|CDD\|223620	COG0546, Gph, Predicted phosphatases [General function prediction only].	3.69213e-26
NZ_CP045480.1\|WP_153036764.1\|720025_720412_+\|cold-shock-protein	gnl\|CDD\|224197	COG1278, CspC, Cold shock proteins [Transcription].	3.0359e-22
NZ_CP045480.1\|WP_153028982.1\|730814_731129_-\|DUF2530-domain-containing-protein	gnl\|CDD\|378488	pfam10745, DUF2530, Protein of unknown function (DUF2530). This family of proteins with unknown function appears to be restricted to mycobacteria.	6.88686e-22
NZ_CP045480.1\|WP_153028972.1\|717368_718331_-\|R2-like-ligand-binding-oxidase	gnl\|CDD\|236242	PRK08326, PRK08326, R2-like ligand-binding oxidase.	0
NZ_CP045480.1\|WP_153028981.1\|729838_730876_+\|WYL-domain-containing-protein	gnl\|CDD\|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	3.07982e-31
NZ_CP045480.1\|WP_153028971.1\|715529_717173_+\|AMP-binding-protein	gnl\|CDD\|236236	PRK08315, PRK08315, AMP-binding domain protein; Validated.	0

>NZ_CP045480.1|WP_153036765.1|720916_722674_-|MFS-transporter
MPTADDAPTGAVPQQSYAPNPDHFYTQPVRRDRDRERQAPPPPPPPPRPGTRSNLPPVPPNRPRGHSGEHERYDTGGFANEQQRRSFEESEHAASEHTKAAHGFEPPPAEAGRGMPRLPKKLTVTRVAALRSRQLTGQAVDAFQRAAKADGADKSGLTSLTYATMLNYASDAAMAIALANTLFFAASSGESKGKVALYLLITIAPFALVAPVIGPALDRIQRGRRLAMCATSAGQALMCVFMALHFDDWGLYPAALGKMVLSKSFMVLKSSVTPRVLPPEITLSKTNARLTVFGLVAGGAFGAVAAGINGIFDSSGALWFTAVICVVGAVQAMRIPSWVEVTEGEVPASLAAHPQKKKRQPMGRQIVVSLWANGSIRLVTGFLFLFAAFAVKAQTEGSGQSPFMQLLLLGVIGGAAGVGGFLGNALGSRMTFGKPDQVVIGCAAATLASTVLAAILAGLATAAIVGLVGATASALAKISLDAVIQADLPEESRASAFGRSETVLQLAWCFGGAVGLLLPPSYWIGFLVISALLAIGVVQTMLVHRGSSLIPGLGGDRPLRPDATSTPPRGMRSGGPAPSRGPAGS
>NZ_CP045480.1|WP_153028976.1|720408_720906_-|DUF2771-family-protein
MRGLGVLAVLAGGAFVLSGCSPVPPPEVTFFADGNTVRTGPFIHCDARVSSCEQNDGAEARLKVRPGKPVQISLPKEIVDTPWLVNVQYQDAAGNLQPVKQEFFSPGRQHAYTATAGPGDQLVVVEIQQISAATAIDGTGAAIEDEQGNPQLVVRGIWTLQVEPA
>NZ_CP045480.1|WP_153036764.1|720025_720412_+|cold-shock-protein
MPTGKVKWYDAEKGFGFVTQDGGADVYIRKAALPQGVAALKAGQRLEFGVADGRRGPQALSVRLLDPPPSVAEARRRPAEELHGLIEDMIKLLELKVQPDLRRNRYPDRKHTKQIAEIMRAVARDLDP
>NZ_CP045480.1|WP_153028975.1|719629_719860_-|hypothetical-protein
MESLPRTKPLLMRAGIGLFAVGMLAVLAVFVLFAAGLEDLPVWLSAVAGLVTPLGLGLGLWALIREHRKAARKAAE
>NZ_CP045480.1|WP_153028974.1|719031_719649_+|HAD-hydrolase-like-protein
MGITVGFDLDMTLIDPRPGMVAALDTLAEESGLPLDGERFAANLGPPLDAVLRGFEAPEERIPGLVDRFREIYPEIVVPSTVALPGAHAALDAVHRAGGRTVVVTGKFGPNAALHIKALGFNVDVLVGELWSTGKAAALTEHGAEVYVGDHLGDINGALAAGAVAVGVTTGPCGRDELAEAGARVVFDSLEEFPAWFESLTPPLS
>NZ_CP045480.1|WP_153028973.1|718343_718976_-|TetR-family-transcriptional-regulator
MSALCQAEVVSEVTSFTQRAKASLREELLVATTALLIEKGYAALRMVDVATRVGVSRQTLYNEFGTKAALVEAVALRTTAEFLDGIHQRFDAAPELLDGVRAATVFTIEHARENPLVAAALGTGPAEDLLPLLTTRAEPVLRAAADAAAEHYRSRAPWLGDECVELLAETVVRLNLSHLVLPTHSPAEAADQVCAVIAPAIEKYSSSTME
>NZ_CP045480.1|WP_153028972.1|717368_718331_-|R2-like-ligand-binding-oxidase
MTTTEKRSGFSSLRRGGLNWDSFPLRLFVKGNAKFWNPADIDFSQDAADWRTLTDDERRSATYLCAQFIAGEEAVTEDIQPFMKAMAATGRFGDEMYLSQFCFEEAKHTEVFRRWMDAVGLTEDLHPYVAENPHYRKLFYEELPSSLGVLADDPSPVNQVRASVTYNHVVEGSLALTGYYAWQKVCTTRNILPGMQELVRRIGDDERRHMAWGTFTCRRHVAADDSMWEVVQQRMGELLPHALGMIQWVNEQFEEPRPFDNDPQEFIEYAADRAQRRLGAIESARGTPVEQIDLDYTPEILEETFGEEDAKAFAEVVATA
>NZ_CP045480.1|WP_153028971.1|715529_717173_+|AMP-binding-protein
MPAVPSYSSGISDVPLLGDTIGDNLARTVAAFGDRDALVERLTGRRWTYAELAADVDALALGLLELGITKGDRVGIWSPNRAEWTLIQYATAKIGAILVNINPAYRSHELKFVLNQAGVRLLVAAESFKTSDYAGMIEQVRPECPGLEHVVLLGTPAWDSLVDNEIDADRLAGIAATLGADDPINIQYTSGTTGFPKGATLSHHNILNNGFFVGELCGYTEADRICIPVPFYHCFGMVMGNLAATSHGACMVIPSQAFEPKAALEAVQAERCTSLYGVPTMFIAELSEPDFGTYDLSSLRTGIMAGSPCPVEVMKQVIERMGMAEVSICYGMTETSPVSTQTRADDSVERRVSTVGRVGPHLEVKVVDPETGLTVPRGEPGELCTRGYSVMLGYWEQPEKSAEVIDAARWMHTGDLAVMDDEGYVNITGRIKDMVIRGGENVYPREIEEFLYTHPDVLDAQVIGVPDARYGEELMAWVRLREGAPELTAESLREFCTGKLAHYKIPRYVHVVDEFPMTVTGKVRKVEMREQAVTLLGLESAASSKHA
>NZ_CP045480.1|WP_153028970.1|714675_715446_-|PhzF-family-phenazine-biosynthesis-isomerase
MRLYLVDSFTDRAFAGNPAGVVLLDAPADEAWMQSVAAELKHSETAFVVTTGEGAKPLRWFTPVAEVALCGHATLATAHVLGGDQVFSTKSGELRCTSAGGWVRMDFPADPSEAVDIDPGAALPGVTVEHVARGKFDLLVVAENAAQVRGLVPDLAAIKAASSSDIRGMTVTAPSDREGIDFVSRFFAPAKGVDEDPVTGSAHCTLAPYWAARLGRNELVGEQASPRGGVVRVELAGDRVTLAGQAVTVFSGDLLA
>NZ_CP045480.1|WP_153028969.1|714274_714649_-|YccF-domain-containing-protein
MKTILNVIWLVLCGFWMAVGYAIAGIICCVLIITIPFGLASFRMANYALWPFGRTLVDRRGSGAFSVLGNIIWFLVAGWWLAIGHLVTGLALCITIIGIPLGVANFKMIPVSLVPLGKEIVPVP
>NZ_CP045480.1|WP_153036766.1|723139_723880_-|glutaminyl-peptide-cyclotransferase
MLTVVAGLTGCAAGSTESPATEELRVQVLETLPHDPGSFTQGLELDGGTLYEGTGLAGKSRLLAGPPGQPPVTQIPLPSPLFGEGVTVTDASVWQLTWQNGFAIEYDKATLTERRRVPYTGEGWGICQQDSGRLVMSDGTGKLTFRDPATFAETGSVSVARDKLNELECAGDSVYANVWQTDEILRIGPDGAITGHVDASGLLSAQERGSADVLNGIAAVPGTDEFLLTGKLWPKMFRVKFVPTTP
>NZ_CP045480.1|WP_153028977.1|723941_724733_+|DUF3027-domain-containing-protein
MTLLLTFDDGSVRESLVEAVELARSAAERDAGAEQVGAHAGVEREDAVSITHLFEAHVPGYRGWRWSVTVATAGPGEPVTVSEVVLRPGPEALTAPTWIPWERRVRAGDLGVGDIFPADENDPRLAPGYLASDDPAVEEVATEIGLGRVHVLSRYGREDAATRWHSGEFGPRSDMARSAPGSCGTCGFFLPLAGSMRAGFGACANDISPADGHVVDVAYGCGAHSEIRVEVTSSIPVAELVYDDSMLDTAPAEEENRASDTSE
>NZ_CP045480.1|WP_153028978.1|724716_727479_+|molecular-chaperone-Hsp90
MTLPSDPFGTESIRTPVLTAWRDSPTRFTEDTNTERDLRVGGYRDRLFVELAQNAADAAKLGGGPGTLRVSIVDGELRVANTGAPLDAAGVASLASLRASAKGEGLVGRFGVGFAAVLAVTDEPRVVSTSGGVRFSAARTRAESGRDGEVPVLRLPWPTEADEPPLPSGFDTEVRLPLRSDVDGRGLLAELDSAAEDLLLALPWLNRVDVDGRVWLRSEVAGALVITAPDGRTRRWLSHGSLDIDCVWAVQVLASGEPIRLESSVLHAPTPTDERLSLPARLIMTIPIEPSRRRVLPGPGVRAALAAAAAAYPGLVRKLHPEYRPALVPAATFPLSEVDTTLRELITERLRADAWLPAADGDDLTGGRGKVLTAESPKLVKLLAEAIPGLISLSGPRVQRDLAPVGVEPISIAQVIEQITGISRDPAWWRELYDQLLPLLEAHSVSAGELGGLPVPLVDGRTLPGPRGSLLFGAADDLLELLAEAGIGGLRLVHPDAAHPLLERLGAKQAEARDLLESPALREAVDRGAEGSDVVPLAGAVLRLAYEAPVDWLGSLVLPTERGWRRADELVLPTSPLLKIFDPDAIGEDAPLDVLDADFAEDWPADVLAGAGVLDTFVLQEDEDEPEVRDLDLVADDRWPDALRLLAARPNTWRVLSDPASRTARWLAVHAELAGRAPAEWRMPDATTLAGLYDPVPDVGLPDEVLIAAGVRTSLAITDPDDVAELMDRLADDAREVSPGLAARAHTVLADAEFADDYVPSRVRALDGSVCDAEDAVVLDTPWPLGVLPASRVVAALPGAERAARLAELLDLPFASERVVEVRVDSEGEFIPWRELAAVVVVADLLGLELPDGGVRIHEELTVAYGDSSVAVPWWSDGELHAADTSEGLARALAWAMNRWDDRHTITAFLDEPTAESLHA
>NZ_CP045480.1|WP_153028979.1|727540_728626_+|IS630-family-transposase
MPNPKLPELVLSEDEAGMLRCWTRRRKTAQALALRARIVLRCAEGGSNSEIAAELGITRATVAKWRSRFVTDRLDGLLDEARPGRPRTITDEQVEAVITATLESAPANATHWSTRSMAAESGLTQTAVTRIWNAFGLQPHRRESWKLSKDPLFVDKVKDVAGLYLAPPERAVVLCVDEKSQIQALNRTAPVLPMLPGTPQRATHDYTRHGTSSLYAALDITTGKVIGRLHARHRAIEFKKFLTAIDKEVPAELAVHLVMDNVSTHKTPVIKRWLASHPRFVVHFTPTSSSWLNLVERWFSELTTKKLQRASHTSVRALNRDIRAWIETWNDDPRPYVWTKTADQILDSIARYCTRINNSGH
>NZ_CP045480.1|WP_153028980.1|728622_729807_-|NAD(P)-binding-protein
MSTTAARVAFMHNTGKVVVVGGGIGGLALGAGLRRRGYEVAVYDRDTDVTATGGYHITLDERAQSALRTLVEPEIVRRLLASGSALRLRERDVFWDHHGRVLGHGPDLGDSSSVDVDRITLRKLLAEAVGTDLHLGQTVAGAGPGHVSFTDGTSTTAELVVGADGTHSVIARQLAGGPTNQPTGLIGFSGRTRRHDLSPAGQERLGRRSGFAIGPRASALYVGFLDPVGNAALDAPELRMSVTTGPTYIWGVMLAESAETEPLRELRGEQLRDALLDRFREREWAGQLLEVVERAAPDSVAGFRFHAASTNADDLAPWTAGPLTALGDAVHATPPTAGQGAGAAIRDAAGLLNHLGTATSLTEAVTRFEADMRRRGAEVLTLGMDTVRRILAAP
>NZ_CP045480.1|WP_153028981.1|729838_730876_+|WYL-domain-containing-protein
MASTSHRALRLLSLLASRRQWPLPELADRLGVSTRTTRRDIETLRDLGYRITTVHGPDGGYRLGAGHTLPPLLFDHDQALAVAVALQTAPTTTFGLDHDAARALSTLHQVMPAELRAAMESLRLTRLRNYWEFPAPPIDPAALTAVGTAARHRQVLVTETLRPDGTRPDPGEEDFRRARVEPHHLVVWAGRWYLVAYDLADEQWRVHRVDRLHPRPTTQRFTARDLPGGNLAHFVMSSHDRGDTLEVWPCTGSARLDLPAEVVARWAPGGSVVEHLDAEHSRLTLGAWSWAGVAGILATFDADLTDLEPPDLAEACRHLARRLTGATRPAEPTSSRGGRRPAARS
>NZ_CP045480.1|WP_153028982.1|730814_731129_-|DUF2530-domain-containing-protein
MPTRGTLPDVAESINSGAVKSKFQHTPELPERWIALWPVVVAGTGLWALAFLVLLVLKLLNGTGSDVWLWTCVAGVGLGFIGLGIMTWQRAAFRRGSKSAQRGA
>NZ_CP045480.1|WP_153028983.1|731155_732598_+|NCS2-family-permease
MKQKIDGFFKISERGSTPGREVRGGIVTFVTMAYIVVLNPLILGSFSADDAGAHKDAFGNILPVGQVAAVTALVAGVMTILFGLVANYPFAIATGLGVNSLVAVTIAPQMSWPAAMGLVVVNGLVVLLLVVTGVRTMVFNAVPAALKAAIAVGIGLFICLIGLVDAGFVRRVPDAAKTTVPVGLGIDGSIASWPTAVFVFGLVFTGILVAKKVRGAILIGVLTATVVSIALEAVVGAGPSQGTNPRGWNLGYPGLPDHVLGVPDLSLLGEFNFDAWVQIPAITAALLVFTLVLTDFFDTIGTMTGLGKEAGLIDKDGKLPGVGKALFVDSAAAVAGGAASSSSNTVFVESASGIAEGARTGLANVVTGLLFLAAMFLTPLYEVVPVEAAAPALVIVGALMIRQVTEIDFSDFSIALPAFLTIVVMPFTYSIANGIGAGFVSYVLIQLATGKARRVHPLMWVVAVAFVIYFAIGPIRAALG
>NZ_CP045480.1|WP_153028984.1|732642_733074_+|MarR-family-transcriptional-regulator
MPDSVQDRSLASRLRLSVVRLNRRLRAQSATETISLTQISALSTLHKCGALTPGQLAAKEGVQPPSMTRVIAALEELGYVERRPHPTDGRQAIVELSATGVAYIQQTISVREAWLDAQLAELSGEEREVLSRAAEIIDRMAGN
>NZ_CP045480.1|WP_153036767.1|733091_734432_+|MFS-transporter
MGSEAESTPTTTATRESVPVPAERPRRAGTFSSLKVRNYRLFFSGQVISNIGTWMQRIAQDWLVFTLSGNDPVALGIAVGLQFTPILFLSLWAGVLADRADKRKLLLGLQIVAGSQALVLGVLDITGVVEMWHVFVLCFVLGCVAAMEVPTRQSFVAEMVGREQVANAVALNSTIFNMARIVGPAIAGFVIVWVGTGWLFLANAVSTLAVLAGLLLMNPDKLFRGPRVERAKGQLREGLSYVRRRADLMTVMVLVFFVSTFGITFFTSLAIVAANVFGTEADGYGLLSTLLAVGTFTGALMSARRGSRGRPRVRVLLLSALALGLLEVATGYMPTYLAFGIALIPLGYATITFLNTANALVQTAVSPQMRGRVMGLYVLVLVGGNPIGAPMTGWLAEAFGGRSPFVIGGAVSALAALVCAVILVRRGGVSLPRRRFPGLRVLDRRA

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Crispr_ID: NZ_CP045480_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045480_2

1585212-1585325

Orphan

Consensus_repeat	Method
GTCGCCGTTGTTGGCGCGGGCGGTGAGGGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045480_2

>merge|NZ_CP045480|2|1585212-1585325|CRISPRCasFinder
GTCGCCGTTGTTGGCGCGGGCGGTGAGGGTCTTGACGTCGCCTCGTTTGGTGAGTAGCTGGGCCAGTGCCCGCGTGGCGGTTGTGTCGTCGTTGTTGGCGCGGGCGGTGAGGGT

>NZ_CP045480|2|2|1585212-1585325|CRISPRCasFinder
GTCGCCGTTGTTGGCGCGGGCGGTGAGGGT	CTTGACGTCGCCTCGTTTGGTGAGTAGCTGGGCCAGTGCCCGCGTGGCGGTTGT
GTCGTCGTTGTTGGCGCGGGCGGTGAGGGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045480.1\|WP_153029697.1\|1588346_1588598_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045480.1\|WP_153029699.1\|1589493_1589895_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045480.1\|WP_153029684.1\|1575742_1576351_+\|DNA-cytosine-methyltransferase	unknown	unknown	gnl\|CDD\|223348
NZ_CP045480.1\|WP_153029683.1\|1574271_1574853_+\|VUT-family-protein	unknown	unknown	gnl\|CDD\|376842
NZ_CP045480.1\|WP_153029687.1\|1579801_1581001_+\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271189
NZ_CP045480.1\|WP_153029690.1\|1583429_1583936_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045480.1\|WP_153029694.1\|1586649_1587126_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045480.1\|WP_153029691.1\|1583981_1584461_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045480.1\|WP_153029701.1\|1593381_1596057_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276938
NZ_CP045480.1\|WP_153029688.1\|1581205_1581610_+\|Lsr2-family-protein	unknown	unknown	gnl\|CDD\|378714
NZ_CP045480.1\|WP_153029686.1\|1578512_1579328_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238846
NZ_CP045480.1\|WP_153029703.1\|1597387_1598266_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP045480.1\|WP_153029700.1\|1589928_1592892_-\|CHAT-domain-containing-protein	unknown	unknown	gnl\|CDD\|378942
NZ_CP045480.1\|WP_153029696.1\|1588053_1588359_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045480.1\|WP_153029698.1\|1588666_1589494_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045480.1\|WP_153029692.1\|1584457_1584850_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045480.1\|WP_153029695.1\|1587387_1587525_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045480.1\|WP_153029702.1\|1596055_1596652_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238092
NZ_CP045480.1\|WP_153029685.1\|1577614_1578283_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377856
NZ_CP045480.1\|WP_153029689.1\|1581832_1582681_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|252734

Protein	Function_ID	Function_description	E-value
NZ_CP045480.1\|WP_153029687.1\|1579801_1581001_+\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	4.79266e-20
NZ_CP045480.1\|WP_153029686.1\|1578512_1579328_+\|hypothetical-protein	gnl\|CDD\|238846	cd01713, PAPS_reductase, This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly modified version of the P loop, the fingerprint peptide of mononucleotide-binding proteins, is present in the active site of the protein, which appears to be a positively charged cleft containing a number of conserved arginine and lysine residues. Although PAPS reductase has no ATPase activity, it shows a striking similarity to the structure of the ATP pyrophosphatase (ATP PPase) domain of GMP synthetase, indicating that both enzyme families have evolved from a common ancestral nucleotide-binding fold. The enzyme uses thioredoxin as an electron donor for the reduction of PAPS to phospho-adenosine-phosphate (PAP) . It is also found in NodP nodulation protein P from Rhizobium meliloti which has ATP sulphurylase activity (sulphate adenylate transferase) .	5.38917e-08
NZ_CP045480.1\|WP_153029703.1\|1597387_1598266_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	8.41379e-09
NZ_CP045480.1\|WP_153029700.1\|1589928_1592892_-\|CHAT-domain-containing-protein	gnl\|CDD\|378942	pfam12770, CHAT, CHAT domain. These proteins appear to be related to peptidases in peptidase clan CD that includes the caspases. This domain has been termed the CHAT domain for Caspase HetF Associated with Tprs. This family has been identified as a sister group to the separins.	1.20282e-31
NZ_CP045480.1\|WP_153029684.1\|1575742_1576351_+\|DNA-cytosine-methyltransferase	gnl\|CDD\|223348	COG0270, Dcm, Site-specific DNA methylase [DNA replication, recombination, and repair].	1.28396e-38
NZ_CP045480.1\|WP_153029688.1\|1581205_1581610_+\|Lsr2-family-protein	gnl\|CDD\|378714	pfam11774, Lsr2, Lsr2. Lsr2 is a small, basic DNA-bridging protein present in Mycobacterium and related actinomycetes. It is a functional homolog of the H-NS-like proteins. H-NS proteins play a role in nucleoid organisation and also function as a pleiotropic regulator of gene expression.	1.09036e-47
NZ_CP045480.1\|WP_153029683.1\|1574271_1574853_+\|VUT-family-protein	gnl\|CDD\|376842	pfam02592, Vut_1, Putative vitamin uptake transporter.	2.12819e-08
NZ_CP045480.1\|WP_153029702.1\|1596055_1596652_+\|hypothetical-protein	gnl\|CDD\|238092	cd00161, RICIN, Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ligand binding occurs on exposed surfaces of the compact domain sturcture.	0.00177455
NZ_CP045480.1\|WP_153029701.1\|1593381_1596057_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|276938	cd15831, BTAD, Bacterial Transcriptional Activation (BTA) domain. The Bacterial Transcriptional Activation (BTA) domain is present in the putative transcriptional regulator Mycobacterium EmbR and the related Streptomyces antibiotic regulatory protein (SARP) family of transcription factors, which includes DnrI and AfsR, among others. Members of this family contain an N-terminal DNA-binding domain, followed by the BTA domain, and many have diverse domains at the C-terminus. EmbR contains an C-terminal forkhead-associated (FHA) domain, which mediates binding to threonine-phosphorylated sites in a sequence-specific manner. The BTA domain of EmbR contains three Tetratricopeptide repeats (TPRs) and two C-terminal helices. The TPR motif typically contains 34 amino acids, and 5 or 6 tandem repeats of the motif generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein.	1.70208e-29
NZ_CP045480.1\|WP_153029685.1\|1577614_1578283_+\|hypothetical-protein	gnl\|CDD\|377856	pfam07508, Recombinase, Recombinase. This domain is usually found associated with pfam00239 in putative integrases/recombinases of mobile genetic elements of diverse bacteria and phages.	5.09305e-12
NZ_CP045480.1\|WP_153029689.1\|1581832_1582681_+\|hypothetical-protein	gnl\|CDD\|252734	pfam04672, Methyltransf_19, S-adenosyl methyltransferase. This family contains a SAM (S-adenosyl methyltransferase) domain, with a central beta sheet with 3 alpha-helices on both sides. Crystal packing analysis of the structure Structure 3giw suggests that a monomer is the solution state oligomeric form. An unidentified ligand (UNL, cyan) was found at the putative active site surrounded by the residues His57, His170, Phe171, Tyr216 and Met22. The UNL is likely to be a phenylalanine or phenylalanine-like molecule. (details derived from TOPSAN).	1.67527e-72

>NZ_CP045480.1|WP_153029692.1|1584457_1584850_-|hypothetical-protein
MERRIDLSNLDLDRAAEMVAARCAGWRERGLMVAELTWMDNDVSWPAPLLRDRGLVSRPKSLGARVHGEAGEAEFVLYAGGWADVMVIHPHIDEPASEYVELDDVEEFGSVLDRVVGFLASTGRARGRSS
>NZ_CP045480.1|WP_153029691.1|1583981_1584461_-|hypothetical-protein
MNGHEITAAFDDIFDQALIYHGFTDYMRDYEIVAYCTADPRTGIPPAHLRYRFIHCVRASVTSSVTPEIWSRSLDDRLLDFDQGRELDGYGWGARWQVLYPGAKLLSGTAETAMWADRLGCPFHEAVIEANGHTITLVFSDLSVDHIEPGYAPFTVTDL
>NZ_CP045480.1|WP_153029690.1|1583429_1583936_+|hypothetical-protein
MSVTRPGSAVPSGVPPAIDVYVWVEPGDVDGSLSRFIDRYVDVEQPGDPRFPAFVRTFVLREPARGDAEALAELSRDGETERVFSLYLRAIAHYGAIITITEEGALVLGLSLDDPLNAPETTDEASTLMAALMTEFGATGGIAGVELAPPQSTSEWREEYALLRTGTG
>NZ_CP045480.1|WP_153029689.1|1581832_1582681_+|hypothetical-protein
MSPTDAKAPSSVPVGVDPNRASIARVYDAALGGKDNYEIDREVIRQVKAVAPEIRDMAWANRNWLTRAVRCMVGQRIDQYIDCGSGLPTAENVHQVVQRANPDAVVVYTDNDPVVLAHAKALLADESKTYIASADIYEPSQVYDDPIVQNHIDFSRPIGLVHSSTIHHYPGDDYADLMRQYIDPLPSGSWVALSHFYDPERAELSEVARRMEDIFSHSAMGSGWFRTRAEILSMMPGLEIIAPQPGMDATVVPCDLWWPDGPPPRPLTTEQELIGCAVGYKP
>NZ_CP045480.1|WP_153029688.1|1581205_1581610_+|Lsr2-family-protein
MAQKVLVEMIDDIDGEIATQTVPFGLDGVSYEIDLSDDNAANLRDELARYVAAGRRTGGRKVRLATGEPASSSSGADRERARQVREWARENGYQVSERGRISAEITEAFEEAQRKPVAGKAPRKRAARKKVAAK
>NZ_CP045480.1|WP_153029687.1|1579801_1581001_+|tyrosine-type-recombinase/integrase
MPWAEQTGDLSWRVRYRREDDSIGSIPGFPDEKAAKTYIADMGTDQRRGSWIDPVAGQVTIAEFAPEWIDSLDVDQRTEENYQSFLKCHILPQWGSEPFSGMSNLGIRKWEKKLRAGKLAKTTVDSIIKCLSLMLTDAALEKIIAANPLQAKRRGRRRRSKRTPRKIWAEPHEVLAIADQVARYYSPAGALLILVAAWTGARWGELVGLQRHNVHLFDDNTGFIVIDPDNGALHEPNKGPLHLGPPKTEESARTITLPPFLVILLRQHLATLKHDHVFVTTSNQLHRRSNFARRALRPAADGNAQVKTPKIRLVAIKPGLTFHGLRHSHKTWMIDDGVPEIAQALRLGHVLEDKVQETYSHVAVAVEQRLLDALQTRWEKAMAASSTEPEHAHWRSAAA
>NZ_CP045480.1|WP_153029686.1|1578512_1579328_+|hypothetical-protein
MLLLACEGRIPRFDAALFADTGWEPKQVYAQLDTARRLGAQAGIPVLTVSGGNIRHDTLNPNARFVTMPFFVKNPDGSRGMARRQCTGDYKIRPLKKAVREILGYPHPVRVPRGVFVDQAIGISTDEFHRAKDSDVNYTRNIFPLLDLGMSRSDCLTYLRERGLGDVVKSSCIGCPYSGNSRLRYIRDTDPQAWADLIEFDKAIRHGSPRANAGGKPLRGRFFIHRSLLPLDQVDLEATRGRPGADEDDPDGCSPFSCRSGEPSTPGKQRP
>NZ_CP045480.1|WP_153029685.1|1577614_1578283_+|hypothetical-protein
MPTTRPNRVLHQLRRWLRTWHSRGAPRDIPAPAERPLRGTPAEVDVTAEQPVLGTASEATAALVRQGWNVHRPPYGYRTMDVAGTPSGSGRPRTRLTPDPLSAPVVQHIFYWRAVTGLDIDQITQRLNNHPDRYPPPGTSGTWHVSAVTRILTNLKYTGYQALRTRDENNRLRPAEQWVLSDQPAHRALITTALFWAAQNPTTDTRRALRHRLLAQPHDLPA
>NZ_CP045480.1|WP_153029684.1|1575742_1576351_+|DNA-cytosine-methyltransferase
MNAADPAIPAPGAGTHDDLRFVATEGPVIGSLCTGAGGLDLGVAAVLGGRIAWYSEVDPHAARVLAARLPGVPNLGDLRAVDFATVAPVEVLTAGFPCQDISAAGRRAGIEKGARSGLWTNILDAIRVLRPRIVVVENVAALRWRGGGLDRVLGGLAEAGYDAVWRCVRAADIGAAHRRERVFLCAIPTPGWDADDAHPAGP
>NZ_CP045480.1|WP_153029683.1|1574271_1574853_+|VUT-family-protein
MTASSQTASPVPAQAGRLRGRSCASGAALATGWGAAGGYLAVVAGTNWASTHHVLTLGGLAIPAGACLAGLAFTLRDVLHETFSVRGVPAAIAAGTVLSAAVAAPRIAVASAVAFALSEAADSWLYRRWRPHGTLAALAGSNLAGAVADTLVFVPWAFGSLALLPGQLTGKALTTALVLAVVAVWSKRREVPS
>NZ_CP045480.1|WP_153029694.1|1586649_1587126_+|hypothetical-protein
MFRRIFATLGVASAALLGAVVPASAQPDAAPHCQYGSSYGTIVKTAPVSATTGGAQVGTVELCRDSAYNYWGFVIYNEKMTASQYAQVYLQIYRDGSQTSEVTCDSPGGNDHVEPGQTRCWTPKVGGVSGRYTFRAWSDKYSSHTGALLASGRTPITR
>NZ_CP045480.1|WP_153029695.1|1587387_1587525_-|hypothetical-protein
MLAKVYAGSGDHGMAIKHGESSACRRHRIGDFDGEAYALTPLAQA
>NZ_CP045480.1|WP_153029696.1|1588053_1588359_+|hypothetical-protein
MRAAAVAPLAVRPAHDFSLSSLDSYRAIRFVATVIRGYTKPTDLLWSFGELAPGTGTAHRLAGPARGTAMTATLSPRLRVRAAVDLLAGAPSPRYSPRCGC
>NZ_CP045480.1|WP_153029697.1|1588346_1588598_+|hypothetical-protein
MRLLIDRVAEHRGLTPPDWPAQPSPVPTAALADARDQLAGLDVTGAAYELLGCPPPAARRQHLLRPARADRGHRPVQRRPATP
>NZ_CP045480.1|WP_153029698.1|1588666_1589494_-|hypothetical-protein
MDKLLPGLGTKLAERWINLLALPGVLFTVVLAFSWWVHPVGAVDLDALGRRLTEIAVPKQGTQLTMVASIGAVIATACAAIAAELSRPIARIWTGRDRGAILLLQPFLRRRIRKVRAAAPAGYGVPERYLPARATRIGDHIRLAEERIAAQYGVALVRVWPRLWHMSNADERAMTQHAWDRYTAAAMRAAWAVGYLLTGLLWWPAAVAGLLLYLSAWSAARRAAADLQTAIEALTDVKLLDLAAAIGISPAHGKFTPNDGAALETVLDKGSFLTR
>NZ_CP045480.1|WP_153029699.1|1589493_1589895_-|hypothetical-protein
MPSLFRRGGRPEPPPAPDESALALAWFCDRLPGLRAQADRLGWRHELEAEVQAIKAGQPAAKALHNLLLDDPATDRGDGAAGLQELWDPAPIGQRFSCPRFICPERGRGEDAAEPWCNLDDRPMNPSAHRLGP
>NZ_CP045480.1|WP_153029700.1|1589928_1592892_-|CHAT-domain-containing-protein
MPELLRFDFRLSQVTAVWWAANIEHVPYKRNQRTTAGPFCQAGAMRFRALIVAIVVALVAWGVWIGWRRHTLAFLPSENVFGNVGYVYDPVTDRRISLVAAGAIMIVGYPVLILILAGLVTLLFKGHAADIKVGWRALRVRPVVLGGGTAVVAVLPSTCLLVGYAVHAPEGMTFGTYLRTALFTDIPATATIFGAVLVVTVYLMAVGPWMLDYLPRVLRWSRMHRMISGKAAHDDDVAAAVAHLEQDFAVRPYRAQLIVSVLAQMQVAKLDGGEPLDEAILRTMALIPSLEEPAWTHRISPLLYDLDARYQFAETLVKTYARSDSRAHLDVAIRLLEGMHRRPPITTARRRRALIALTLAKALHLRDWADDRTRAHALVQRAARVAPDEAREARAVLLLAPGSERHELDEALTILRDRCEGERKKLIDGLIRRYEDSNDPADLHEALGLTRERLAEPGEDDTEVLAAHLAALGHLNDLESPELVDALDRVDALADPPWRLAHQATTLKGFRAMERGDIDGALTHFDQVLRLVNEAASLGLSRADRQSVLRQSRLAPTTAAALALMAGRVERAVELLEVSRTVIWWQVRELRGADTGDHAPRLAEVRAALRQPNYPEAGSGQDVLAAHRHAMTRAELAREWDEMVQRRAFGHRIRFAELREAARGGPVVMINTSTRRCDAIIVLADQDPIHVPLPGLTESDATVWAEGLLHAETRRMNVRAIAPRLWDIVAAPVLAAVEPHLGPSRRIWWCPTGALTSVPVHMAGRDEDAVLDKVVSSYTPSLWSLLDARRGDRTSTVEPTMLITSLRDTPPRPDGTTWAALPHAEEEADLICARIPAATKLAEREATVAAIRAALPGSTWAHFACHGDLRGLVLQDGSLGIDELTDMDLEGNEVAFLSACVTAVPDSQNLDEALHPAAALHLQGFSHVIGTLWHIRSEDGPTVADDFYTHLLDDTSPALALHRAQRRLRIVAPDDPARWAPFVHIGP
>NZ_CP045480.1|WP_153029701.1|1593381_1596057_-|tetratricopeptide-repeat-protein
MLRLLGEVVVGEGGPRELGSPRQRCVLAALAVDAGRVVTVERLMQRVWGDDAPVRARETLYSYVSRLRRTCGVTIDRRSGGYTLTAQAVDLHVFRDLCAEARQHQDKAAELLTEALQLWRGEALTGLDGEWAGAERGRLAREHLTARLDLVEARLRWEEGGELLEEVAALAEEHPLDERVAGQLLRALAQSGRRADALEHYRLFRARLIDELGVEPGAALREEHQRLLADSPVTTRPAVVLKQLPAAPALFVGREDELSRLGDAEFSGTLVISAIAGAGGIGKTWLALHWAHRHAAQFPDGQLFVDLRGFAPEGRPMDPATAVRGFLDALGVEKMPSDPHAQAALFRSLVADRRMLLVLDNAAGSAQVAPLLPGGGSCTVVVTSRDRLPGLITGHNARHVPLDVLPGVEARALLTHRIGAERCGAEPEAVDRLTALCGGFPLALAIIAAHAHTRPNTRLADLADDLHDLGLSAFDDGDPATSLPAVLSWSVHALTPRQAEAFRLLALAPGEDIGLEAAVSLTGWARADTRLALRGLEQASLLSQYAHGRYRMHDLVRNHAASTSDRSPETDEALRRVVDFYLYSSVSADKVLNPPREPVVPAPVDVHIPKDTAEAMAWFDAEHGCVLAALHMAAETGWHRTAWNLVWALETYHRRRGLLRLRLEVWQIALAAVEHVPDHAVLTHRLLGRAYADLGWHEKADDHLRQAFDLAVRDDDRTNQIHIHRTRAAARAARGDMHAAYAHAAEALRLCEGLGKPVWQARALNAVGWYAAHLGHHAEAYERCAAALELFERNEDPEGVATTLDSLGFITYGRGDHDQAVAHYEAALARYDELGFVSDMADTYDRLGHAHLALGRPNRTRAAWQLAVELYTAQQRDEDAERVRWQLIELG
>NZ_CP045480.1|WP_153029702.1|1596055_1596652_+|hypothetical-protein
MTTHLPTHHHARAELRRAGHCKEFTRPVGQSRRHRGVRRKGETMVRRIGSAVLTLTVAAGVTLATAAPASAATNKFAVPSGTGCLDGYNEHRPTELYTTGCNTGSFQRWGWGGVFNSRTQLRSSAVTSHCIQQDIENTAVSLEPCVNGRSTQAWLVQGRPGSLVIRSAAAPELCLTRAAENVDMAPCTSGRPAAWVLR
>NZ_CP045480.1|WP_153029703.1|1597387_1598266_-|alpha/beta-fold-hydrolase
MSWNTSSRPRSAPTFVLVHGSGSSSFMWAPIQRELALLGHRSFAVDLPGHGLDAQYPVAYQAPQDLDAWAAEPSTLATVTLRDNADLVVDTVRRLAEHGPVVLVGASLGGTAISVAGNLVPDLVDRLVYISAWSCVERANPIEYFGEPEFAANLMGPLAALNVGDPAELGVGRANYRTADQDLLTAMKAAIAADITDEQFRAFLNILQPDESIAVMTGDARVEADTWGTIARSYIRLTEDRSIPIAMQDRLIAEADALTPDNPYDVHTLDTSHVGFVFRAPEVAAILDKLSV

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Crispr_ID: NZ_CP045480_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045480_3

2640703-2640798

Orphan

Consensus_repeat	Method
CATGGAGGCGGCTCGTGGCTGAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045480_3

>merge|NZ_CP045480|3|2640703-2640798|CRISPRCasFinder
CATGGAGGCGGCTCGTGGCTGACAATCGCGAAGCGCACCACGAGTGCCGACCGGGTGCGGGTGCCCCGCAGAACAAGGAGGCGGCTCGTGGCTGAC

>NZ_CP045480|3|3|2640703-2640798|CRISPRCasFinder
CATGGAGGCGGCTCGTGGCTGAC	AATCGCGAAGCGCACCACGAGTGCCGACCGGGTGCGGGTGCCCCGCAGAA
CAAGGAGGCGGCTCGTGGCTGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045480.1\|WP_153030562.1\|2632277_2633471_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340887
NZ_CP045480.1\|WP_153030563.1\|2633987_2634752_+\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|367243
NZ_CP045480.1\|WP_153030574.1\|2650961_2652491_-\|flotillin-family-protein	unknown	unknown	gnl\|CDD\|259798
NZ_CP045480.1\|WP_153030570.1\|2645227_2646115_+\|peptidase	unknown	unknown	gnl\|CDD\|226119
NZ_CP045480.1\|WP_113693268.1\|2652487_2652694_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045480.1\|WP_153030567.1\|2642530_2643598_-\|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl\|CDD\|187652
NZ_CP045480.1\|WP_153030564.1\|2634770_2635802_+\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|237284
NZ_CP045480.1\|WP_153030573.1\|2649804_2650815_-\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|236196
NZ_CP045480.1\|WP_153030557.1\|2625853_2627320_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224048
NZ_CP045480.1\|WP_153030572.1\|2649206_2649785_-\|TIGR03086-family-protein	unknown	unknown	gnl\|CDD\|274424
NZ_CP045480.1\|WP_153030568.1\|2643669_2644572_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_CP045480.1\|WP_153036950.1\|2646222_2647602_+\|3-deoxy-7-phosphoheptulonate-synthase-class-II	unknown	unknown	gnl\|CDD\|366662
NZ_CP045480.1\|WP_153030558.1\|2627316_2628048_+\|methyltransferase	unknown	unknown	gnl\|CDD\|237872
NZ_CP045480.1\|WP_153030561.1\|2629845_2630658_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377194
NZ_CP045480.1\|WP_153030571.1\|2647624_2648950_-\|wax-ester/triacylglycerol-synthase-family-O-acyltransferase	unknown	unknown	gnl\|CDD\|274360
NZ_CP045480.1\|WP_153036949.1\|2633467_2633872_-\|nitroreductase-family-deazaflavin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|211538
NZ_CP045480.1\|WP_153036948.1\|2630757_2631927_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|225371
NZ_CP045480.1\|WP_153030560.1\|2629069_2629831_+\|phytanoyl-CoA-dioxygenase-family-protein	unknown	unknown	gnl\|CDD\|368580
NZ_CP045480.1\|WP_153030559.1\|2628047_2629073_+\|pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|107204
NZ_CP045480.1\|WP_153030569.1\|2644587_2644962_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227324

Protein	Function_ID	Function_description	E-value
NZ_CP045480.1\|WP_153030562.1\|2632277_2633471_+\|MFS-transporter	gnl\|CDD\|340887	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MdtH and similar multidrug resistance (MDR) transporters from bacteria and archaea, many of which remain uncharacterized. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtH confers resistance to norfloxacin and enoxacin. MdtH-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.48743e-45
NZ_CP045480.1\|WP_153030563.1\|2633987_2634752_+\|TetR-family-transcriptional-regulator	gnl\|CDD\|367243	pfam02909, TetR_C, Tetracyclin repressor, C-terminal all-alpha domain.	3.78886e-10
NZ_CP045480.1\|WP_153030574.1\|2650961_2652491_-\|flotillin-family-protein	gnl\|CDD\|259798	cd03399, SPFH_flotillin, Flotillin or reggie family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily. The flotillin (reggie) like proteins are lipid raft-associated. Individual proteins of this SPFH family may cluster to form membrane microdomains which may in turn recruit multiprotein complexes. In addition, microdomains formed from flotillin proteins may be dynamic units with their own regulatory functions. Flotillins have been implicated in signal transduction, vesicle trafficking, cytoskeleton rearrangement and interact with a variety of proteins. They may play a role in the progression of prion disease, in the pathogenesis of neurodegenerative diseases such as Parkinson's and Alzheimer's disease and in cancer invasion, and metastasis.	5.30124e-42
NZ_CP045480.1\|WP_153030570.1\|2645227_2646115_+\|peptidase	gnl\|CDD\|226119	COG3591, COG3591, V8-like Glu-specific endopeptidase [Amino acid transport and metabolism].	4.6395e-05
NZ_CP045480.1\|WP_153030567.1\|2642530_2643598_-\|NAD-dependent-epimerase/dehydratase-family-protein	gnl\|CDD\|187652	cd08948, 5beta-POR_like_SDR_a, progesterone 5-beta-reductase-like proteins (5beta-POR), atypical (a) SDRs. 5beta-POR catalyzes the reduction of progesterone to 5beta-pregnane-3,20-dione in Digitalis plants. This subgroup of atypical-extended SDRs, shares the structure of an extended SDR, but has a different glycine-rich nucleotide binding motif (GXXGXXG) and lacks the YXXXK active site motif of classical and extended SDRs. Tyr-179 and Lys 147 are present in the active site, but not in the usual SDR configuration. Given these differences, it has been proposed that this subfamily represents a new SDR class. Other atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.0177e-141
NZ_CP045480.1\|WP_153030564.1\|2634770_2635802_+\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|237284	PRK13108, PRK13108, prolipoprotein diacylglyceryl transferase; Reviewed.	4.02019e-134
NZ_CP045480.1\|WP_153030573.1\|2649804_2650815_-\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|236196	PRK08241, PRK08241, RNA polymerase subunit sigma-70.	1.02479e-173
NZ_CP045480.1\|WP_153030557.1\|2625853_2627320_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224048	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only].	1.16674e-122
NZ_CP045480.1\|WP_153030572.1\|2649206_2649785_-\|TIGR03086-family-protein	gnl\|CDD\|274424	TIGR03086, TIGR03086, TIGR03086 family protein. This family, like pfam07398 and TIGRFAMs family TIGR030834, belongs to the larger set of probable enzymes defined in family TIGR03083. Members are found primarily in the Actinobacteria (Mycobacterium, Streptomyces, etc.). The family is uncharacterized.	1.238e-17
NZ_CP045480.1\|WP_153030568.1\|2643669_2644572_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	2.82763e-41
NZ_CP045480.1\|WP_153036950.1\|2646222_2647602_+\|3-deoxy-7-phosphoheptulonate-synthase-class-II	gnl\|CDD\|366662	pfam01474, DAHP_synth_2, Class-II DAHP synthetase family. Members of this family are aldolase enzymes that catalyze the first step of the shikimate pathway.	0
NZ_CP045480.1\|WP_153030558.1\|2627316_2628048_+\|methyltransferase	gnl\|CDD\|237872	PRK14968, PRK14968, putative methyltransferase; Provisional.	1.68879e-16
NZ_CP045480.1\|WP_153030561.1\|2629845_2630658_+\|hypothetical-protein	gnl\|CDD\|377194	pfam04016, DUF364, Putative heavy-metal chelation. This domain of unknown function has a PLP-dependent transferase-like fold. Its genomic context suggests that it may have a role in anaerobic vitamin B12 biosynthesis. This domain is often found at the C-terminus of proteins containing DUF4213, pfam13938. The structure of UnioProtKB:B8FUJ5, Structure 3l5o, suggests that the protein has an enolase N-terminal-like fold and this Rossmann-like C-terminal domain. Structural and bioinformatic analyses reveal partial similarities to Rossmann-like methyltransferases, with residues from the enolase-like fold combining to form a unique active site that is likely to be involved in the condensation or hydrolysis of molecules implicated in the synthesis of flavins, pterins or other siderophores. The protein may be playing a role in heavy-metal chelation.	2.77078e-11
NZ_CP045480.1\|WP_153030571.1\|2647624_2648950_-\|wax-ester/triacylglycerol-synthase-family-O-acyltransferase	gnl\|CDD\|274360	TIGR02946, Putative_diacyglycerol_O-acyltransferase_Mb3115, acyltransferase, WS/DGAT/MGAT. This bacteria-specific protein family includes a characterized, homodimeric, broad specificity acyltransferase from Acinetobacter sp. strain ADP1, active as wax ester synthase, as acyl coenzyme A:diacylglycerol acyltransferase, and as acyl-CoA:monoacylglycerol acyltransferase. [Unknown function, Enzymes of unknown specificity].	2.70897e-110
NZ_CP045480.1\|WP_153036949.1\|2633467_2633872_-\|nitroreductase-family-deazaflavin-dependent-oxidoreductase	gnl\|CDD\|211538	TIGR00026, Hypothetical_protein_Rv1261c/MT1299/Mb1292c., deazaflavin-dependent oxidoreductase, nitroreductase family. This model represents a family of proteins found in paralogous families in the genera Mycobacterium and Streptomyces. Seven members are in Mycobacterium tuberculosis. Member protein Rv3547 has been characterized as a deazaflavin-dependent nitroreductase. [Unknown function, Enzymes of unknown specificity].	8.25267e-09
NZ_CP045480.1\|WP_153036948.1\|2630757_2631927_+\|MFS-transporter	gnl\|CDD\|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	3.79469e-16
NZ_CP045480.1\|WP_153030560.1\|2629069_2629831_+\|phytanoyl-CoA-dioxygenase-family-protein	gnl\|CDD\|368580	pfam05721, PhyH, Phytanoyl-CoA dioxygenase (PhyH). This family is made up of several eukaryotic phytanoyl-CoA dioxygenase (PhyH) proteins, ectoine hydroxylases and a number of bacterial deoxygenases. PhyH is a peroxisomal enzyme catalyzing the first step of phytanic acid alpha-oxidation. PhyH deficiency causes Refsum's disease (RD) which is an inherited neurological syndrome biochemically characterized by the accumulation of phytanic acid in plasma and tissues.	1.09519e-25
NZ_CP045480.1\|WP_153030559.1\|2628047_2629073_+\|pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|107204	cd01561, CBS_like, CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine. Deficiency of CBS leads to homocystinuria, an inherited disease of sulfur metabolism characterized by increased levels of the toxic metabolite homocysteine. Cysteine synthase on the other hand catalyzes the last step of cysteine biosynthesis. This subgroup also includes an O-Phosphoserine sulfhydrylase found in hyperthermophilic archaea which produces L-cysteine from sulfide and the more thermostable O-phospho-L-serine.	1.81682e-64
NZ_CP045480.1\|WP_153030569.1\|2644587_2644962_-\|hypothetical-protein	gnl\|CDD\|227324	COG4991, COG4991, Uncharacterized protein with a bacterial SH3 domain homologue [Function unknown].	0.00583612

>NZ_CP045480.1|WP_153030564.1|2634770_2635802_+|prolipoprotein-diacylglyceryl-transferase
MNTAAASFLASIPSPDRGVWHIGPIPIRAYALCIIAGIVVAIWLGERRWVARGGTKGTILDIAVYAVPFGLVGGRLYHVATDWHRYFGEGKDPIQALNIVNGGLGIWGAIALGGVGAWIGCRRKGIPLPAVADAIAPGIVIAQGVGRLGNYFNQELYGGHTDLPWALEIYARVNPDDPRIEDTLNGVALNNIPIDTVHPTFLYELLWNLGVALLVIWADRKLRLGHGRAFALYVAGYTLGRTWIELMRTDAATLVFGVRVNVWVSILVFAGALVYYFAAKSRGEREVPESLKGKDGDQPDEDLIDEETAVVPTTNGNDDATESGEDGKAEETAERSEKRDTKD
>NZ_CP045480.1|WP_153030563.1|2633987_2634752_+|TetR-family-transcriptional-regulator
MATDNGSDPARSLAILWRTREVASRKGKPELNVDRIARVAIELADADGLESLSMRKVAEKLGVGTMSLYTYVPGKAELVDVMVDLVQAETARPAEDDGDWRAKLELIARENLALYQRHPWLLQASHRSVLGPNVIEKYEWELRALEGIGLTEIEMDSVLTLLIGQAQVSARGRAEISRVERSSGLTEEQWWTQNAPLLDQVIDYNRFPVASRVGAAAGEAHHASYSPEHAFEFGLARILDGIEVLIGGRGDAGS
>NZ_CP045480.1|WP_153036949.1|2633467_2633872_-|nitroreductase-family-deazaflavin-dependent-oxidoreductase
MNRLFVGLQRTGLKLGGMYLLTVPGRKSGKPRTTPISLMEHQGGRYVVGGFPGADWVRNASAAGAGTLSHGRRHESVRLVELSAEQARPVLREFPAKVPSGVSMMTSAGIVESDSPDEFEALAGRCAVFRIESI
>NZ_CP045480.1|WP_153030562.1|2632277_2633471_+|MFS-transporter
MNRARPALLVALAIDNFGTGLFLPLTLVYLTRVVGLPLALAGTIVPLGTVAGLLVPPLAGRLTDRVGARLVVIIAQLVQAAGVFAYLLAGSAVTVMVAAVLVAAGQQLFYCSLYALVADVAGDVPKDHPFAVVGMVRAASFGAGGLVAAVLLTGFGPVGFRLAIGANAVTYLVAALVLLLCLRAPATRFLSPPRRLAAGPLRDRPYLTLILISGLFGLSLDVFLIGVPVFVLEQLHGPSWLPGAIIALLTLCTSVGGTLALRLTHRLSRIDAMRFGSLLYALWWLGCLGALLVPRAAQPGYLLAVTLIIATANLVFGPRANALAEAAAPRAARGRYLAAFQYAFTTAQVVAPAVVALFSVAVWLPWVVVAVCAVLAVFGLSGLAARLPAHAVHPPPS
>NZ_CP045480.1|WP_153036948.1|2630757_2631927_+|MFS-transporter
MARVLGPVLLASAVSLLPFTVFSTFLVPISADAGTSVAAMGGLRGLGGLAALGVGAAVAPLLDRVPKQYTAGGGLVLLGLSAVVGAAGQFLALAAFCLLVGAATSVLNPALAADAADRFGSGAAAGRAATLVTATQSLTAMLAAPLVALPALLWGWRGNLVAVAVISLALAVVFFRRRPTPVAESDAAPRLGYLASFRALAGVPGAVPLLLVALLRTAAFMGYLSYLAAFYDSRFELDPELFALVWTLSGASFFVGNLLAGRYTSAERPWIRPERMLTVSLLVALASVAGFYFATNLVWALVLTALLGAAHATVAACVVTLLVRRCGPLRGSALGVNAAGMSLGTFTGAAVGGIGLGVAGYPGTAVAFGAITLLALVAALFVRPEPSVA
>NZ_CP045480.1|WP_153030561.1|2629845_2630658_+|hypothetical-protein
MESVAALTEAVLAGEFGPSPAERTVTSAFWLHHTTRLAGGGVTYRNHYLLLRVGSGFGACSFEEGELEADFCATASGEPLDKLIGDDRMPVRIAALDAYLADARPHRDAGAEQVVLPIGTPEVRARARDEAIAGLLEIRPGARVALIGVVNPLVAAITERGGECLPCDLNLRTTQWGQPVSREMDEVLDVADAVVATGMTLSNGSFDRLLARSRERGLPLVVYAQTGSAVARAFLGHGVTAVSAEPFPFSQFSAEPSTVYRYRAVSDRAS
>NZ_CP045480.1|WP_153030560.1|2629069_2629831_+|phytanoyl-CoA-dioxygenase-family-protein
MNDPGYRVLPGLFGGDELARLAEAAEVVQREVLAKAASGRTSVEVWPDGHRLESVDGTTLHWEPEAPGTIRSLAPVAHLHPEFEALWTDPRLTAPMADLLGVAEPGPFVSKLNFKRAGVGSEFAWHQDFPFWYCCAGPHARDIATAMIYLDDAGTGNGALSVIPGSHLDGPAPRDLAEPTGLLVDASKVDSSQERVLDLSAGSVLMFPGTLVHRSAPNRSDRDRRTLLFCFQPAGRPRLADLTYRPEMLADLP
>NZ_CP045480.1|WP_153030559.1|2628047_2629073_+|pyridoxal-phosphate-dependent-enzyme
MHDHFAEAVKEPDLIRVREDLLCVRFETMKIYSALGAVRQLLETGAVRPGDTLIDSSSGIYAHALALACNRYGLHCHIVGSTTIDATLKVQLEILGATLEQVQPSRSLKLDQSLRVRRIAEILRENPSYHWMRQYHDEIHYLGYRAVAEQIDRAVPPGPLSLSGGVGTGASTGAIASYLGELGREVTLIGVQPFGSVTFGAERVADPEMIIAGIGSSIEFENVRHELYDRIHWISFDYAMSAAVDLLRSSGVFAGLSAGAAYLAAHWEHEREPERLHVFLAADTGHRYAESAYSRHREAHDLHRMRPREVGVLSELACPWSAMDWARRPACARDHDVLGVA
>NZ_CP045480.1|WP_153030558.1|2627316_2628048_+|methyltransferase
MSEESWALHASLPPTLSTAEILEVNPPRNDLHTVRSHTYRDWEFELPPGVFRPGETSKMIHDRLLDGRIPVAGKTYVAMGSGLGVEAVTAGIAGAARIYALDVHPASVAATEAHYRRFVGDTPPLHAIVSDLFTAFPDKAQADVITFNPPAVALKTSEDPDVVRNVCVGAGITARFFDQVLARDLLAPGGEIHLIVSNTANLRDIIAHAIESGFVPEVRERRTWPDDDVQTYLFRLRAKGDTA
>NZ_CP045480.1|WP_153030557.1|2625853_2627320_+|ATP-binding-cassette-domain-containing-protein
MSALVEVDSLSARAGDAILLRDIGFRLWPGKVTALVGPSGSGKTTAALSLLGESAPGVRLSGSVTVAGSSVLDGELPRGLRGGVVSYLPQHPGSALNPARRIGTTLRELAKLHRANESTEDVVAEALRAAQLPGDRKLLRRFPHQFSGGQRQRVALAQALVCGPRVLVLDEPSTGLDTVTRLRLAGELAELAATGLAILLLSHQHDLVRALADHVVLLDHGRVAATGTPDEVLGEVAPPAGDWAAPSAAEALLELRGLSASVRPRGRQPILRDIDLALPPGGRIGVVGPSGSGKTTLARCVAGLHERYTGELLLDGRPLPVLRKRRRDLRRRVQYVWQEVRGSFDDRRPVLDQVARTGIRLRGLDSAAARAEAVELLAELGVTEETAARHPDGLSGGELQRAALVRALLAEPEVLVCDEITTALDPGTARKVTTLLARLNEQRGTALLWISHDLGLIAAVTSEVLVLDEGMATGLGQDRPSLDRKESV
>NZ_CP045480.1|WP_153030567.1|2642530_2643598_-|NAD-dependent-epimerase/dehydratase-family-protein
MSNGSMNNKVALVVGAHGVIGSNLVDHLAALGDWTVIGLSRRGGEPSPNVRHLAVDLLDADDSREKLGGLTDVTHVFYAAYQDRPTWAELVPPNLAMLVNVVDAIEPVATGLRHISLMQGYKVYGAHLGPFKTPAREDDAGHLPPEFNVDQQEFLERRQEGKSWTWSAIRPAVVGGTALGNPMNLAVSIAVYATISKELGLPLRFPGKPGAYDKLLEMTDAGLLARATVWAATDERGANQAFNINNGDLFRWSDLWPKIARYFGMETAPPLPMSLDVVMADKEPLWDRIVTEHNLESTPYQRVSAWPFMDFVLSWDYDMFADGTKARRFGFHEFVDTEEMMWRLFDELRKRHIIP
>NZ_CP045480.1|WP_153030568.1|2643669_2644572_+|LysR-family-transcriptional-regulator
MSTLRRFEYLVAVVDEGSFTRAAERLHVTQPALSHQIRALEQDAGGVLLERLPRAIRLTAMGRAMLPHARAALADAERAVCAAKQAAGLEVAELRVATVFSVSLGVLPPVLREWNRRHPGVAITLAEHRHTGELREAMLAGQADLAVGPRPVDWDGPVRTLGEEEFVLVLPEEDPADPADPGKPVRLADFADRGWVHYAPENGLAEVLDQACAAAGFSPRAAISTAQTAVAPLLAAAGLGPALVPSNVLPDGFGGRVLRLDPPVRRELTVYTRGVPDPVSAAFTELLAEAKTLMAKASSP
>NZ_CP045480.1|WP_153030569.1|2644587_2644962_-|hypothetical-protein
MNTILRPARLAGLAAVGAVLATVVTGTVASAAEPVAAAPATVECGQYWDADFNTNGVNIRSGPGTGYAVVGAGYVGDKIDICTSTSGTFVDCGGGRRSDWWDEIINRRTGVRGFISQCFVNYER
>NZ_CP045480.1|WP_153030570.1|2645227_2646115_+|peptidase
MRRASVLTAIGLALGALLTAPAVGQAQTAADYWTPEKMRAAVPIERLLTAPRASAGEVLAGLPEVVPAAFPTTGAPWTGGGDVVKTAGRVFFTMGGQNASCSGDAVTSANKSTVITAGHCVKYQGAFHTNWVFVPAYDNGNAPYGEWPATSTLTTPQWEASEDINYDVGAAVVDQVGGQSLTDVVGSQGIAFNQPRNQNMYTFGYPAADPYDGTTLIHCSGGTFTDFLLTQDHGMSCGMTGGSSGGPWFLQFDEQTGRGVQASVNSFGYVFLPGFMFGPYFGAEAQALYNEAQAA
>NZ_CP045480.1|WP_153036950.1|2646222_2647602_+|3-deoxy-7-phosphoheptulonate-synthase-class-II
MDVPVDTLPELPPLPPELRARLDEALARPAAQQPDWPDQGLTRRVRGVLESVPPITVPAEIDRLHQRLAMVANGEAFLLQGGDCAETFESNTEPHIRANLRTLLQMAVVLTYGASLPVVKVGRIAGQYAKPRSASTDSLGLPVYRGDIVNSLVAKPELRVPDPGRMIRAYANAGAAMNLVRALTAAGMADLAQLHDWNRDFVRTSPAGERYEALASEIDRGLRFMSACGVTDTSLHTTEIFASHEALLLDYERSLLRLDNADADNPKLYNLSSHFLWIGERTRQLDGAHIAFAELLHNPIGLKIGPTTTPEQAVEYVRRLDPRNEPGRLTLIARMGNGKVREVLPAIVEKVEASGHKVIWQCDPMHGNTHEASTGYKTRHFDRIVDEVQGFFEVHRMLGSYPGGIHIELTGEDVTECLGGAQDISDIDLAGRYETACDPRLNTQQSLELAFLVAEMLRS
>NZ_CP045480.1|WP_153030571.1|2647624_2648950_-|wax-ester/triacylglycerol-synthase-family-O-acyltransferase
MLDGQLSGLDVAFLCLEGERTPMHMGAVVTFDGPVDTDRLALLLAARAARIPKLRKHIRPTLLPPGGAVWAEDPGFDPAGHIHVHHVSSLYEPEPLAAFASLWIAEPLDMDRPLWDLSLVTGLPGGRFAVLLKLHHALTDGAGAFAIGSGLLDELPGARAIRATTAKTVRSKPARSTLSLLKDGFSSAFAQAAEGASIASSVLRAARPYPTSPISAPNADERSLGFVRLDLADLRRVRKAHGGTTNDVVLAIVAGALRSWLVNRGQRADDRTLRALIPVSVRARQQGNTDGNQLSGYLCDLPVGLDDPVARLHAVRRSMEHAKAKGTATGPGAFPILANRLPAPVHRLATRAAGRVAPLLFDTVVTNVPMPGLPLTLDGARLREIYPLVPLPPNQALGIAVSIYRDAVHIGLQANGEAVADLGSLRDAFDKSAAKLVGTCP
>NZ_CP045480.1|WP_153030572.1|2649206_2649785_-|TIGR03086-family-protein
MPMPPPPGALAGGADLLERAVSYALGCLRLVTAGAMANATPCRDWDLRALLAHLDDALTALAEAAESGRVGLDPVPPVPGDPATAVRARAGELLGALAGEPHAGLVSVAGAPMTAAVIAGAGALEVAVHGWDVARACGHDRPLPPALAAEMLELSALFVTAADRPERFAAPIELTREAAPGDRLLAFLGRRA
>NZ_CP045480.1|WP_153030573.1|2649804_2650815_-|sigma-70-family-RNA-polymerase-sigma-factor
MTETVSPGVEGDFLTQADPYRRELMAHCYRMLGSVHDAEDLVQETYLRAWRAYDRFEGRSSLRTWLYRIATSACLTALESRGRRPMPTGLGAPGCEPEDDLQERHEVPWLEPVPDALTGADGADPAAIVTSRESIRLALVAALQHLPARQRAVLILRDVLKWRAAEVAELMDISTAAVNSILQRARAQLEKIAPTENEVTEPSAAGQRELLDKFVTAFEAKDIPAIISLFTEDAVWEMPPFAGWYLGAERIARHLATRCPCRPGHTRLLPTWANGQPAFGTYLRDGDGERFRAFNLQVLTVGPAGITHVANFVDANLFAVFDLPESLPADYPAATG
>NZ_CP045480.1|WP_153030574.1|2650961_2652491_-|flotillin-family-protein
MTSHFYWGVTDVDPLILAGVVVGAIIVLFVLLRMLYKVAEPNEALIISGWGVRVQRSETADSLGFKIITGKGVLVIPGFQTARRLSLDTRGANLQVSCVTKQGLPVTVRAVVIYKVGDDFASIANAARRFLDQQDGMNNTIHELFAGHLRSIVGGLTIEEMIHNRDALTGEIRSSSANEMIKLGLVVDSLQIQEIDDESGYILNLGKPHAAAVAASARIAEAQRDQEATEAEQIAAAQKAGAIRESEIKQAGFQAEVDQARAKAGQSGPLAEATARQEVVVQETRAAELEADLAEQRLQSEVRKPADARAYDTRTSADAERDAAIAKAQAEAKETELRAAADATKVKTAAEAEAQATRARGEASAAATKATGDAQAHAAKAQGLAEAEAARAKGLADAEAAKAKGLAEADAIKARAAALAENQEAVVAQQLAERWPEIVEAGAKAFGSVDHMVVLNGADGVSDMFSKALSLGGTGLGLARQLMEAMGQTSKPAEPETNGSVVPTTTDLR
>NZ_CP045480.1|WP_113693268.1|2652487_2652694_-|hypothetical-protein
MIGSRGRVTGTIGPGLIGEVLLSVRGGTEAFYAYPADGEERFENGTQVLVVDFEAPRTVYVQRWQPLV

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Crispr_ID: NZ_CP045480_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045480_4

6007732-6007826

Orphan

Consensus_repeat	Method
AGCCCGCAGATGCCGGGCATGCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045480_4

>merge|NZ_CP045480|4|6007732-6007826|CRISPRCasFinder
AGCCCGCAGATGCCGGGCATGCCGCAGGTGCCGGCCGCGGGCCTGCCCGGTGGCGGACCGGGCTCCCCCGGCAGCCCGCAGCTGCCGGGCATGCC

>NZ_CP045480|4|4|6007732-6007826|CRISPRCasFinder
AGCCCGCAGATGCCGGGCATGCC	GCAGGTGCCGGCCGCGGGCCTGCCCGGTGGCGGACCGGGCTCCCCCGGC
AGCCCGCAGCTGCCGGGCATGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045480.1\|WP_153033275.1\|6011148_6015981_+\|type-IV-secretion-protein-Rhs	unknown	unknown	gnl\|CDD\|225750
NZ_CP045480.1\|WP_153033274.1\|6010524_6011130_+\|YbaB/EbfC-family-DNA-binding-protein	unknown	unknown	gnl\|CDD\|376829
NZ_CP045480.1\|WP_153033271.1\|6003925_6006319_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|379262
NZ_CP045480.1\|WP_153033266.1\|5998244_5998835_-\|pyridoxamine-5'-phosphate-oxidase	unknown	unknown	gnl\|CDD\|274679
NZ_CP045480.1\|WP_153033270.1\|6002299_6003118_-\|NAD(P)H-binding-protein	unknown	unknown	gnl\|CDD\|187578
NZ_CP045480.1\|WP_153033273.1\|6008690_6009461_+\|ESX-secretion-associated-protein-EspG	unknown	unknown	gnl\|CDD\|379414
NZ_CP045480.1\|WP_153033278.1\|6022392_6023100_+\|DNA-primase	unknown	unknown	unknown
NZ_CP045480.1\|WP_153037311.1\|6026550_6027312_-\|DUF5131-family-protein	unknown	unknown	gnl\|CDD\|377854
NZ_CP045480.1\|WP_153037309.1\|6003167_6003755_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225107
NZ_CP045480.1\|WP_153033280.1\|6027461_6027617_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045480.1\|WP_153033281.1\|6028112_6030122_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045480.1\|WP_153033268.1\|6000118_6001291_-\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|223157
NZ_CP045480.1\|WP_153033264.1\|5996618_5997230_-\|amino-acid-transporter	unknown	unknown	gnl\|CDD\|224198
NZ_CP045480.1\|WP_153033277.1\|6020436_6021840_-\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271177
NZ_CP045480.1\|WP_153033267.1\|5998868_6000107_+\|glycoside-hydrolase-family-27-protein	unknown	unknown	gnl\|CDD\|269893
NZ_CP045480.1\|WP_153033276.1\|6016675_6020059_-\|TM0106-family-RecB-like-putative-nuclease	unknown	unknown	gnl\|CDD\|274603
NZ_CP045480.1\|WP_153037310.1\|6006472_6006871_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045480.1\|WP_153033269.1\|6001624_6002290_+\|DUF4142-domain-containing-protein	unknown	unknown	gnl\|CDD\|379301
NZ_CP045480.1\|WP_153033279.1\|6025346_6026576_+\|three-Cys-motif-partner-protein-TcmP	unknown	unknown	gnl\|CDD\|275267
NZ_CP045480.1\|WP_153033265.1\|5997299_5998199_+\|ArgP/LysG-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|235144

Protein	Function_ID	Function_description	E-value
NZ_CP045480.1\|WP_153033275.1\|6011148_6015981_+\|type-IV-secretion-protein-Rhs	gnl\|CDD\|225750	COG3209, RhsA, Rhs family protein [Cell envelope biogenesis, outer membrane].	3.36308e-45
NZ_CP045480.1\|WP_153033274.1\|6010524_6011130_+\|YbaB/EbfC-family-DNA-binding-protein	gnl\|CDD\|376829	pfam02575, YbaB_DNA_bd, YbaB/EbfC DNA-binding family. This is a family of DNA-binding proteins. Members of this family form homodimers which bind DNA via a tweezer-like structure. The conformation of the DNA is changed when bound to these proteins. In bacteria, these proteins may play a role in DNA replication-recovery following DNA damage.	3.61845e-10
NZ_CP045480.1\|WP_153033271.1\|6003925_6006319_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	1.43196e-08
NZ_CP045480.1\|WP_153033266.1\|5998244_5998835_-\|pyridoxamine-5'-phosphate-oxidase	gnl\|CDD\|274679	TIGR03618, Rv1155_F420, PPOX class probable F420-dependent enzyme. A Genome Properties metabolic reconstruction for F420 biosynthesis shows that slightly over 10 percent of all prokaryotes with fully sequenced genomes, including about two thirds of the Actinomyces, make F420. The Partial Phylogenetic Profiling algorithm identifies this members of this protein family as high-scoring proteins to the F420 biosynthesis profile. A member of this family, Rv1155, was crytallized after expression in Escherichia coli, which does not synthesize F420; the crystal structure shown to resemble FMN-binding proteins, but with a recognizable empty cleft corresponding to, yet differing profounding from, the FMN site of pyridoxine 5'-phosphate oxidase. We propose that this protein family consists of F420-binding enzymes. [Unknown function, Enzymes of unknown specificity].	2.9568e-09
NZ_CP045480.1\|WP_153033270.1\|6002299_6003118_-\|NAD(P)H-binding-protein	gnl\|CDD\|187578	cd05269, TMR_SDR_a, triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs. TMR is an atypical NADP-binding protein of the SDR family. It lacks the active site residues of the SDRs but has a glycine rich NAD(P)-binding motif that matches the extended SDRs. Proteins in this subgroup however, are more similar in length to the classical SDRs. TMR was identified as a reducer of triphenylmethane dyes, important environmental pollutants. This subgroup also includes Escherichia coli NADPH-dependent quinine oxidoreductase (QOR2), which catalyzes two-electron reduction of quinone; but is unlikely to play a major role in protecting against quinone cytotoxicity. Atypical SDRs are distinct from classical SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	2.99626e-54
NZ_CP045480.1\|WP_153033273.1\|6008690_6009461_+\|ESX-secretion-associated-protein-EspG	gnl\|CDD\|379414	pfam14011, ESX-1_EspG, EspG family. This family of proteins contains the the EspG1, EspG2 and EspG3 proteins from M. tuberculosis. These proteins are involved in the ESAT-6 secretion system 1 (ESX-1) of Mycobacterium tuberculosis which is important for virulence and intercellular spread. Proteins in this family are typically between 254 and 295 amino acids in length.	1.20504e-49
NZ_CP045480.1\|WP_153037311.1\|6026550_6027312_-\|DUF5131-family-protein	gnl\|CDD\|377854	pfam07505, DUF5131, Protein of unknown function (DUF5131). This is a family of bacterial and phage proteins of unknown function. There are three highly conserved cysteine residues in the disposition, Cx6Cxxc, amongst many highly conserved residues.	8.59651e-149
NZ_CP045480.1\|WP_153037309.1\|6003167_6003755_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	5.64471e-23
NZ_CP045480.1\|WP_153033268.1\|6000118_6001291_-\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|223157	COG0079, HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase [Amino acid transport and metabolism].	7.38643e-64
NZ_CP045480.1\|WP_153033264.1\|5996618_5997230_-\|amino-acid-transporter	gnl\|CDD\|224198	COG1279, COG1279, Lysine efflux permease [General function prediction only].	1.26175e-57
NZ_CP045480.1\|WP_153033277.1\|6020436_6021840_-\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271177	cd00796, INT_Rci_Hp1_C, Shufflon-specific DNA recombinase Rci and Bacteriophage Hp1_like integrase, C-terminal catalytic domain. Rci protein is a tyrosine recombinase specifically involved in Shufflon type of DNA rearrangement in bacteria. The shufflon of plasmid R64 consists of four invertible DNA segments which are separated and flanked by seven 19-bp repeat sequences. RCI recombinase facilitates the site-specific recombination between any inverted repeats results in an inversion of the DNA segment(s) either independently or in groups. HP1 integrase promotes site-specific recombination of the HP1 genome into that of Haemophilus influenza. Bacteriophage Hp1_like integrases are tyrosine based site specific recombinases. They belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	1.04549e-24
NZ_CP045480.1\|WP_153033267.1\|5998868_6000107_+\|glycoside-hydrolase-family-27-protein	gnl\|CDD\|269893	cd14792, GH27, glycosyl hydrolase family 27 (GH27). GH27 enzymes occur in eukaryotes, prokaryotes, and archaea with a wide range of hydrolytic activities, including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-N-acetylgalactosaminidase, and 3-alpha-isomalto-dextranase. All GH27 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein. GH27 members are retaining enzymes that cleave their substrates via an acid/base-catalyzed, double-displacement mechanism involving a covalent glycosyl-enzyme intermediate. Two aspartic acid residues have been identified as the catalytic nucleophile and the acid/base, respectively.	1.05711e-135
NZ_CP045480.1\|WP_153033276.1\|6016675_6020059_-\|TM0106-family-RecB-like-putative-nuclease	gnl\|CDD\|274603	TIGR03491, TIGR03491, RecB family nuclease, putative, TM0106 family. Members of this uncharacterized protein family are found broadly but sporadically among bacteria. The N-terminal region is homologous to the Cas4 protein of CRISPR systems, although this protein family shows no signs of association with CRISPR repeats.	1.18995e-65
NZ_CP045480.1\|WP_153033269.1\|6001624_6002290_+\|DUF4142-domain-containing-protein	gnl\|CDD\|379301	pfam13628, DUF4142, Domain of unknown function (DUF4142). This is a bacterial family of unknown function.	6.40195e-14
NZ_CP045480.1\|WP_153033279.1\|6025346_6026576_+\|three-Cys-motif-partner-protein-TcmP	gnl\|CDD\|275267	TIGR04474, conserved_hypothetical_protein, three-Cys-motif partner protein. Members of this family occur regularly as a partner to as a member of family pfam07505, which has been called a phage protein but which seems to occur also in other contexts. Members average about 400 residues in length, but the conserved region covered by the model averages 260 residues and excludes the C-terminus. Conserved motifs suggest enzymatic activity. Note that its frequent partner protein (see pfam07505) has a three-cysteine motif that resembles the Cx3CxxC motif of radical SAM proteins, and that in one branch (see TIGR04471) actually becomes Cx3CxxC. We suggest the name three-Cys-motif partner protein (tcmP), and renaming pfam07505 to three-Cys-motif family protein.	5.61529e-24
NZ_CP045480.1\|WP_153033265.1\|5997299_5998199_+\|ArgP/LysG-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|235144	PRK03635, PRK03635, ArgP/LysG family DNA-binding transcriptional regulator.	7.80147e-146

>NZ_CP045480.1|WP_153037310.1|6006472_6006871_+|hypothetical-protein
MPTQATVVALAARVERLQKQVASGDLALDPAVGDEIRGMLTEQMDQVDVWLRKAIDLGRQAPLGQNPVAEAMAGKFQQRAGDADSALAGVLVPYRELLAKAHETVGTAMQRYGDFEHQSIDLLRTANGETNA
>NZ_CP045480.1|WP_153033271.1|6003925_6006319_+|tetratricopeptide-repeat-protein
MVNDGQRTDESAFGALLLRHRRAAGLTQADLAENSGVSIRALSDLERGRAQGAQRRSAAALADALGLVGDDRQEFLEAARQGRRRTPRAEEEIEAAPSVTLPPAVPDLLGREGELAKLHEEASSDAPGGVVVSVVGHPGVGKTALAVTAAHQLRARFPDGAFALDLRGMDEEPVTPRSALTQLLRALSVPPQQIPVTVPEQSALFRSLLSGRRILLLLDNAADEAQVRPLLAASSGCLTLITCRSALAGLESGRWLWLEPLVDLGAVELLTAIAGETRVRAEPRATAELVALCGNLPLAVRIAGNRLASRPHWTIAYLTTQLRNERTRLSSLSAGDLQVRSAFEMSHRRLSPAARLVFRRLAIVPGPDFGAELAGVATGMAEADVQVHADELVDANLLQAAASPGRYQFHDLIRIFAVERLEAEEKPADRDRHRRTMLDHLLLTASEAGRAFMPDALVAPTHAARRFTTREAAGVWLDVEAGNWLAAHREAPVEGLHREVVDLARALHWYSDGRTQQRPWDEIFQRGVESARVLGSQLDEAVLLNFVGWARYFCFGDNDGGLAAHNEALAVAIEIGDKAEQAWALGYRGSVLMRLGRLDEALESVRRAVDLAEVLGFWTGEGTIRNALGRILRVLGKHEESLEVHRRVLEDAQARRAEANPDTRRFQRSVTLLDVGSTLLAMRDWHEAARTLREARGYFEESGFRIEEAETALQEGIARREAGEYVVARECFGLALNVFTGVANRWKRANTLAELITMLELMGDPTADEYRAGALALCAELKTDAAAALAARLRHEG
>NZ_CP045480.1|WP_153037309.1|6003167_6003755_-|helix-turn-helix-transcriptional-regulator
MTVLAADPFVFAGVSGELKSKPGVHLVDGRADVVVAVPDSTRKLHEVLAGIDPEARVVLVADDPRPAELLTAVEHGLAVLLPRQEATTARLLHAINDAYQGRGALPAEQLGELLKGVTRLQREVLEPRDLTLSGLSRRETDVLRLLAEGRDTAEIAAEMAYSERTVKNILHGLLTRLDLRNRTHAVAHALRLGLI
>NZ_CP045480.1|WP_153033270.1|6002299_6003118_-|NAD(P)H-binding-protein
MRKILVTGATGNIGGRVLAALTDTGAEVRAFARDPRGLPGGVAGDLSHPDTLVPALRGVDRVFLVWPGIPVQPRVVELIAEHARQVVYLSADVADLADGEQPSSFHQEIERQIRGTGLDWTFLRAIDFATNTLAWAPQIRRGVVELPYGRAARSLIHERDIAEVAAHVLTTEGHHGGKYVLTGPESIQQAELVRTIGEAIGREVRWRELAPEVALERFTEAWGDRAFAAARLAAWKSFVETPERVTDTVTRLLGRPARDFRTWAAEHAGDFR
>NZ_CP045480.1|WP_153033269.1|6001624_6002290_+|DUF4142-domain-containing-protein
MRHTRRTTRLRPRTLVITIAIVALAALVPVVISLQSGDNTANAVTAPGQFDAAQQGEAGTAGPVTELDKTFLVKVRQAGLWEIPAGRLAQTNGSSEAVKRAGHHLLEGHSRLDQLVREDAQILGVELPNEATEEQQQWVTQMEGLRGEEFDKFFANVLRSSHGKIFATIGEVRAGTQNDLIRRHAREANQTVLDHMEVLEDTGLVTGETLAEVETAVTPPK
>NZ_CP045480.1|WP_153033268.1|6000118_6001291_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MRHSAGGADALFGQTAHSPSYFELARAGEQGPPPIDFCIPCNPYFPTPAMFDLLAGNLEAVLKFYPSDAATIGRQLARVLGLNPATLAMANGSTELITWIDHLWVRESLAVPVPTFGRWTDQPLETGKRVDMFPLRESGGFELDVDAYIRFIRARGSRVAVLCNPNNPDGRYLPRREVLRFADELGDLDLVVIDESFVDFVEQERNPSVAAEVALRPNVVVLKSLGKNFGLHGIRFGYLVANPALAGKMSRTLPKWNLNSLAETVIFMLAEYAEEYRESLYLLARDRYLMGVELSRLPELTVYPSQANFLLVKLSAGIDGTALRDDLYARHGILIRECGNKLGMSNQFLRLVVRPEADVTRLVAGILDHTRPGEDAGENTGAFEMVRSVS
>NZ_CP045480.1|WP_153033267.1|5998868_6000107_+|glycoside-hydrolase-family-27-protein
MIPVRRALAALTGLTVLTATAAGPAQAAEPAPTPPLGWNSWNTFGCDINEQLIRDTADSMVSSGMAAAGYEYVVIDDCWFDPERAADGSLRAHPERFPSGIKALADYIHGKGLKFGIYQVPTEVTCAQRGGAYPGATGSLGHEAQDAQTFADWGVDYLKYDWCSPEGTLEEQIESFTLMRDALRATGRDILYSINPNSYHPDKNGAKYDWSDIADQWRTTEDIKPVWRTGNPNTYPMGVTDIIDVTEPLRDWAGPGHWNDPDMLEVGVYNVEGFPGLTDTEAAAHFSMWAMLAAPMIAGNDLRSIPDGVHSILTNRAVLAVNQDPKGVAADRVRDDGDLEVWARPLAGGDVAVALFNRSEKAAKISTTAKEVGAPGKRHRVTDLWTGKKWLSHGTISAEVPSHGVTLLRLRR
>NZ_CP045480.1|WP_153033266.1|5998244_5998835_-|pyridoxamine-5'-phosphate-oxidase
MRQQQVTNHVNSAFRAHGTSGAAPGVRSEVMIPVLGEPRASVPIMYGAPAPPGGLLPWEWAHRRLVDARNYWIATTRPGGRPHCRPVWGVWLDTGFWFSTGSLAVGNLSSNDQITVHLEDGQEVVIVEGTARTGHDREALRPLCEAYGPKYDYPISPREDGTVVDDLGLGGPVFHVVPEVVFGWDRDMSSPTRWRF
>NZ_CP045480.1|WP_153033265.1|5997299_5998199_+|ArgP/LysG-family-DNA-binding-transcriptional-regulator
MMTELPLDQVRTLLAVVDEGTFDAAAAALHVTPSAISQRVKALEQRTGRVLLLRTKPVRPTESGEVVVRFARQLARLELDARTELGMAETGEPARLSIAVNADSLATWFLPALAEVPGHLKTFFELHREDQDHTTALLREGVVMAAVTSSPDPVAGCSVRALGKMRYLPMASPAFRARWLADRPLRQALPEAPVVLFDRRDDLQDRLTRKLTRGRGAGGGRHYLPSSEAFVAGVAAGLGWGMVPVAQAEPHLRDGTLVDLAPEHAIDVPLFWQQWKLDSPALAAAADVVTKAAAAALNR
>NZ_CP045480.1|WP_153033264.1|5996618_5997230_-|amino-acid-transporter
MGNLLLAAAAGFGTGLSLIVAIGAQNAFVLRQGIRRDGVLAVVAICAVSDAVLIALGVAGVGAVVTAWPGAVTAVGLIGGAFLLCYGVLAARRVFRPAAMQVDPARPGSPRRAVLTCLAMTWLNPHVYLDTVLLLGSVAAARGDLRWAFGLGAVLASLCWFTALGFGARLLTGFFARPSSWRWLDGLVAATMITFGVLLVGGA
>NZ_CP045480.1|WP_153033273.1|6008690_6009461_+|ESX-secretion-associated-protein-EspG
MNTPDFVLSAHEFDIVWGELDLGRLPYPLDVPSTGRTVEQRAQLAAEVYRELGDRGLARGQRVDADLESLLLLLSQFDVAVDAIGHIGYPVRALAAARGNAAVLAVLAGGELWLKEIRPTALARSIVEVLPSADAGPGQAMSVPYQALAEAAEPQEDEDDPYGGDLDERVVLSRAGVSRNDAGALVELANNRKAGGQLGVTIGGGRRTERVPTLVTWFDTHQGRYLMVREDSWLSIAPADNERIEQRVATVLAGAR
>NZ_CP045480.1|WP_153033274.1|6010524_6011130_+|YbaB/EbfC-family-DNA-binding-protein
MTNPLGALGQDPSQVEADIDRWAQGFAEKAQRYQAAQAQVDQIRTTASSPDGTVKVTVRADGSVTDLQFSDRIRQIAPAELSAMVMRTMQTAQSQVVGQVGETMQANLGDEDQQTRSLMMDELRTRFPEPDPEVEAAGEAVSEKWDYDEGDDTPRTPPPPAPPAPPAPPAPPAPPAAGPTRRRRPDDGEDDIDPDFDPLRD
>NZ_CP045480.1|WP_153033275.1|6011148_6015981_+|type-IV-secretion-protein-Rhs
MGNPLVAEVKDSTTAISGVPILESISETSKAIESGDWAAGVLGAAGTALDALGMAMDPFGSILAAGVGWLIEHCGPLSDALDALTGNPDEIKAHSETWKNVGTELSSISADLAKMIEEDTASWLGPAGDAYRTRGADTATLIAGAQTAAEGASSGIATAGEVVGAVRSLVRDIIAELVGHMISWALQVLFTLGIGLAWVVPQVVSAVAKTAMKIADITKKLVQALSKLSPLLKKLGDSFGDAAKALKNIKGGNPPKPETTRGGGGDTTPSGAGPTPKPPPGQSNGGNTTPSSAPKDPPPTPTPTPSPPPASKTPDPTPTPTPTPPPAPKSNTTPSSAPVAPRDTSVPPSKRNCETDPVDIATGEVILEQTDLELPGLLLERVHVSSYRAGRWFGPSWASTVDQRLEVDGNDICYVGPDGVILVYPLPATGEPVLPIEGPRWPLSRHADGTFTVDQPRRALHFTGTGPVRRLHAVDGSDGERIELLYGDDGAPALLTHSNGVRVRFQVDGGRLTELSVLGGGRTPDVVVLSYRYDDRGRLTEVVNSSGLPTRFDYDNDGRMTGWQDRNGVWYRYVYDADGRCVRTVGDGAFLDGAFTYDRERLLTTYTDSLGNTKVFELNQAGQTIRETDALGHVTAFEWDRYDNLLSRTDPLGRVTRYEYAPDGTPTRVTRADGSVVELEHIGDVLTSVSVTDGDQVWRRYYEAGAAPEPTSDAVGVASAYRTDLPANQPPQPDSADRDQFGRPRSLPEVGGGRVLLGWTVDGKRASRTGPRAERAVWRYDGEHNEVEHIDELGQVTRRDYGPFDTLVATTDPTGARTEHTYDTELRLVATTDPTGRVWTYRYDAAGRLTGQTDFDGRSWTYEYDPAGQLVRSTAPDGAVTGYRYDVLGNLVELHTPDGVTTYAYDPVGEVVRVASAHSVVEFERDEFGRVVRESVDGHAVTFAYDADRNTIRRRTPSGAESVWSFDEAEQPVSLTTAGHTVRYRLDEDGRTLAREVDGASVLEQSFGPGGRLTAQQLTAASVPVQRRGFEYRADGSLAGVHDELTGPARFTRDAAGRITAVSTAHGQEELRYDPAGNLIGWSGGAGLSFDYDHLGRRVRQRLGDRTWEYVWTGELLTELRTPDGNRWLYRYDPLGRRTAKQCVRPDGSVAESFRFVWDGTVLIEQEHVDVHGARWITTWDRLPGTAAPVTQFERGPAGARFHSVVTDALGTPTELVDERGHLAWSGRRTLWGRELPSPGARAAIPLRFPGQYADAESGLHYNVFRYYDPATARYLSQDPLGLEAGPNPTAYVTDPFAEFDALGLMNCSTTTPSGSGSGNPPSTNPPAKHNAGNSGGSSATPTPAPNKGKRKADGSGNNPPAKKPKKSNPDPFAKRPAFNKATKDEHAKRKDDPNDPAYKSGGDYDGRHIISWQTMRDNTKAWVDEKFPPGHPDRDAMTKKYVDELKQMNTKIENLPLGEGEINSSIGRVVDNFKTVESRIDGTYTPSGKNQPDAPMTPSEAFDKSAGYSKELRSEFADPIFKAADDIKDPAERKEFLDDVKFSSDFDWPGGTTAEHKEWKNIRNEFDNLGKNPGDYTPAHVDDLISRFKALDAPSGQHPGVSEWNSRPK
>NZ_CP045480.1|WP_153033276.1|6016675_6020059_-|TM0106-family-RecB-like-putative-nuclease
MYTPSDLADLLECEHRSVLKQALSAGLPGAPRPGSGADQLAVKHGRAHEEATLNRLRGEKHTVVEIDHVDHATAVSDTAVALWSGAPVVYQAVFDDGEFTGRADFLLRDDQGRYEVYDTKLARRARPAAVLQLTAYADALRSAGWPAGPNMHLLLGDGSTRTLRVDDFLPLLRRLRARLLARPAHLPEQLWADPRPGCASCGFADHCAQGREADRDLSLVAGMRSDQRRKLVEAGLGTIDALAKAEPGDRPRELSAASFTTLRAQAKIQVKQDETGEVSYEIIDEEPLAALPQASPGDVFFDMEGDPYALGGTGLEYLFGAVTTDGGQRFTPFWAHSRPEEKRAFERFVDFTMARLAEHPGAHVYHYAPYEVTALKQLAALHGTREEQVDELLRGGVLIDLYAVVRKALLVSQRSYSIKYLEPLYMPEARDGDVKTAVSSIEAYEEYLTLSQLGENEQAAEVLRGISDYNEYDCVSTLRLFEFLHQIREKAGIEPLPAPDESEVDALLRDSADDVAAQRRAERAARLAALVDPLLDGLPADPVDFTESERARALLAASVGYHRRETNPAWWEHFRQLAAPLTDLETDTSCAVPISIQAGEWVPPTGRARTAKRALTIACDPEHPHPFTTGDKVRLRYGQESRDARVVAASAEELTLEESSKVDETTADRPQAVLPGDPVRPAPKDEAVADLAQLVVDQLPKLPPHPGVDLLRRLPPRLRKGNKLPAPGEDLVATVIEAVDALDGSALAVQGPPGAGKTYLAGKLIAHLVRAGKTVAVTSNSHKAVENVLTAAMANAPELPCAKRPRKAPDPELPWEQPKDNNALARWRTEHDTGHLVGGTAWTFANAALRAEPFDVLIVDEAGQFALADALAVSMCARNLVLLGDPQQLPQVVQGTHPAGAEASALGHLIGEADVIDPELGYFLDQSRRMHPAVCDPVSRLSYAGRLHAHPTAADRGIDGVPAGLYVSEVDHRGNTTRSVEEAAEIVEIVRALHGRKWTDRGEVRPLDDGDILVVAPYNLQARVVGRALEKAGFPGVRVGTVDRFQGQEAPVVLTTMTSSSAVDLPRGLDFLLSRNRLNVALSRAQAVAVLVCSPRLVEADIRTVDQMRLVSGLVGLMAGAEPFDQA
>NZ_CP045480.1|WP_153033277.1|6020436_6021840_-|tyrosine-type-recombinase/integrase
MADQKIPPIGVKLSGDIEELAGPKGTSFRARVRWTIPGSRKRRSLSQVHETYEAASDWIEKMQLAAASGLDPHVATMDLAAYGKANMKLALRNLEQKSIGAYLAGWRKRVVPTLGHIPVRMVTFGVVDRAVQGWIAEAVGRSSIKNSLAVLVRVMEQALRDGLVDRNPARVTGWQRDYTQAEDELDDPRALALPNWETLKRLADALVAASSTEYPGWGDVVIFAACTGARIGEVSGCRVRDIDRAEWTWTVRRQTTPAPGGLIDKGTKGKRAREVPIIEKIRELVDRRIALTDGTKDARLFTGPRGGRISTAVLRDATSWDDVVGRLGLEHLRRHDLRHTALTWFADAGVPVHHLQKIAGHGSLTTTQRYLHPNRKTVVDAGELLSEHLSGSGAEPTAMESRSLPELDAEVIDLKSAKPGERARAAARSYWRRFGQYPNVPTLVKLASVSRGTAWNALAELRERPAV
>NZ_CP045480.1|WP_153033278.1|6022392_6023100_+|DNA-primase
MAERVWLDVPFREKDEAKAAGARWDPGVKRWYAPRPGMTALERWAAQPDVPALLPGEDRGFGSGLFVDLVPKSCWFTNVRYCISERDWERVRRMLLGRAGHRCEVCQREEDREVRRWLEAHERWSFDWSARVQKLVRLICLCTDCHQATHYGLAQVRGQDAAAFEHLRAVTGWSEQDTQAHIEGAFEVWAQRSQVDWHLDLSMLTGAGIALAKPPAAATRTGIAIEELRAGRSQP
>NZ_CP045480.1|WP_153033279.1|6025346_6026576_+|three-Cys-motif-partner-protein-TcmP
MSASQEFFRDRKAQAVFKHEILARYPVVFAAKAGLGRPVVFLDGYAGRGEYEDGTEGSPVLLSKHAERVDSFRTVTGIYVERNKADYLKLKEVMAKRGRPQDYVRGGDFRDLLPEILTIARGAALFAFLDPFGTALDRDQLVAQLLNGRGHAPTEVLLHVSISTVARMGGLLRKRRQEGKPLSPADQKTVDHANRFLGGTWWQKHFEPVTDATDERRATEAALAVAAEYQAGIRRDAHCMSLSMPIRHKPNQLPKYLLVLFTRHQDGLWWFADAVGKAGREWEGAWRGAELRQAKQRAEKNDEDALFSAEQLLPEPDSFDIDEYVKQNRASWERIIGQNIRRVLDLEGSFVLAQRLDEVYARVFGAASYVHVRAAVKSLHEQQVVQNTGKGNYFFREPIIPIRPTQATA
>NZ_CP045480.1|WP_153037311.1|6026550_6027312_-|DUF5131-family-protein
MSDGSSIEWTEATWNPTTGCDRVSAGCDNCYALTLAKRLKAMGSAKYQNDGDPRTSGPGFGVATHTAALGEPFRWRQPRRVFVNSMSDLFHAKVPIDFVRRVFAVMEATPQHTYQVLTKRSRRIRRVAQSLDWPANLWLGVSVEDERVVDRIDDLREVPAAVRFLSCEPLLGPLPELNLDGIGWVIVGGESGPGARPMAATWATEIRDQCQRAAVPFFFKQWGGRTPKAGGRELDGRTWSEYPTAVRPSPVSA
>NZ_CP045480.1|WP_153033280.1|6027461_6027617_+|hypothetical-protein
MTDASPRLCNKCGTEPTEDQKIGILCRGCRAMIEASDPLGGRIGQRADSAS
>NZ_CP045480.1|WP_153033281.1|6028112_6030122_+|hypothetical-protein
MTSTITPPTDVVGEETQMLRPVRTLPDVADPDVVRAVRRDAQKHLGMSELGAKAMSTMWANPGEVLPQISSPHRMRITGGDLLYIQAPAWTARLVPDPANPRIASSYAYQLAFREDADQAIRFERITPAQPMTPAELQTSAASQKDLVKQLNDSIAKTCKANEPYPPIAEQGIMDAPFGVMTQFNFSDGGNPIAVPVVREGSTRVSYGLEYLGLTAEDVLFRMPASTRPLRSLISDVNGVVQSPAETVRLEDLAKARVATVQFILIVGFHPDQGDTPDLAAAVKAKVAQEHINTKNNWKPSDRDATMADDCLASALNAGVVSADEHRWLSGDMSRDTAAKLGFGTYTEDRFLELVYLFATPEPKVHRAIRQPIAFVLARDNVRSGVQVRRTSKLPLAVELTVRELRFGDSGAAIDRIAKVLAGGANIAGKHVARPTSRTVEQLEEQAQAELDERKDTTPGPAGIELALRALYHGAYHGAFHIPRNDLGARSDRRPVHHVLQDMLGTPSGILQLGRIVENGRAGTPPVTIDEHGITVLAADGNPAPLTNEVIRYQLYPRGAATNEKTSDPVAAARKVMLEHMRDTCNAFSDFKMADGGRGGAEGLSADVAEQLIRQLTSMKEDADTWFRNGLKHAAMAELAAMSKPEHHADEESDEADVAAFPETQDGAS

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Crispr_ID: NZ_CP045480_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045480_6

6519442-6519511

Orphan

Consensus_repeat	Method
GCTGGCCCGGCTGCGATTGCCCCGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045480_6

>merge|NZ_CP045480|6|6519442-6519511|CRISPRCasFinder
GCTGGCCCGGCTGCGATTGCCCCGGTTGTGGCGCCTGGTAACCCGGCTGGCCCGGCTGCGATACCCCCGG

>NZ_CP045480|6|6|6519442-6519511|CRISPRCasFinder
GCTGGCCCGGCTGCGATTGCCCCGG	TTGTGGCGCCTGGTAACCCG
GCTGGCCCGGCTGCGATACCCCCGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045480.1\|WP_153037348.1\|6510300_6511101_+\|DUF692-family-protein	unknown	unknown	gnl\|CDD\|377459
NZ_CP045480.1\|WP_153033670.1\|6527235_6528141_+\|chitin-binding-protein	unknown	unknown	gnl\|CDD\|376983
NZ_CP045480.1\|WP_153033658.1\|6511097_6511445_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045480.1\|WP_153033667.1\|6520791_6521403_-\|DUF4178-domain-containing-protein	unknown	unknown	gnl\|CDD\|379368
NZ_CP045480.1\|WP_153033663.1\|6516428_6516983_+\|DUF3000-family-protein	unknown	unknown	gnl\|CDD\|378665
NZ_CP045480.1\|WP_153037351.1\|6528808_6529999_+\|acetyl-CoA-C-acyltransferase	unknown	unknown	gnl\|CDD\|273881
NZ_CP045480.1\|WP_153033661.1\|6513819_6515238_-\|protoporphyrinogen-oxidase	unknown	unknown	gnl\|CDD\|237009
NZ_CP045480.1\|WP_153033666.1\|6520332_6520764_-\|DUF4247-domain-containing-protein	unknown	unknown	gnl\|CDD\|379437
NZ_CP045480.1\|WP_153033668.1\|6522830_6524087_+\|ribonuclease-D	unknown	unknown	gnl\|CDD\|223426
NZ_CP045480.1\|WP_153033662.1\|6515240_6516320_-\|uroporphyrinogen-decarboxylase	unknown	unknown	gnl\|CDD\|234644
NZ_CP045480.1\|WP_153033671.1\|6528140_6528680_+\|DUF305-domain-containing-protein	unknown	unknown	gnl\|CDD\|367619
NZ_CP045480.1\|WP_153033669.1\|6524951_6527204_+\|chitinase	unknown	unknown	gnl\|CDD\|119365
NZ_CP045480.1\|WP_153033660.1\|6513139_6513832_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377705
NZ_CP045480.1\|WP_040406084.1\|6522051_6522768_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225107
NZ_CP045480.1\|WP_153037349.1\|6511415_6512687_-\|carnitine-dehydratase	unknown	unknown	gnl\|CDD\|367110
NZ_CP045480.1\|WP_153033672.1\|6529995_6532104_+\|3-hydroxyacyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|236864
NZ_CP045480.1\|WP_153037350.1\|6524136_6524742_-\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|366102
NZ_CP045480.1\|WP_153033664.1\|6516979_6518554_-\|polyamine-aminopropyltransferase	unknown	unknown	gnl\|CDD\|235139
NZ_CP045480.1\|WP_153033665.1\|6518550_6518973_-\|DUF350-domain-containing-protein	unknown	unknown	gnl\|CDD\|377187
NZ_CP045480.1\|WP_153033659.1\|6512759_6513089_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP045480.1\|WP_153037348.1\|6510300_6511101_+\|DUF692-family-protein	gnl\|CDD\|377459	pfam05114, DUF692, Protein of unknown function (DUF692). This family consists of several uncharacterized bacterial proteins.	1.61452e-108
NZ_CP045480.1\|WP_153037351.1\|6528808_6529999_+\|acetyl-CoA-C-acyltransferase	gnl\|CDD\|273881	TIGR01930, 3-ketoacyl-CoA_thiolase, acetyl-CoA acetyltransferases. This model represents a large family of enzymes which catalyze the thiolysis of a linear fatty acid CoA (or acetoacetyl-CoA) using a second CoA molecule to produce acetyl-CoA and a CoA-ester product two carbons shorter (or, alternatively, the condensation of two molecules of acetyl-CoA to produce acetoacetyl-CoA and CoA). This enzyme is also known as "thiolase", "3-ketoacyl-CoA thiolase", "beta-ketothiolase" and "Fatty oxidation complex beta subunit". When catalyzing the degradative reaction on fatty acids the corresponding EC number is 2.3.1.16. The condensation reaction corresponds to 2.3.1.9. Note that the enzymes which catalyze the condensation are generally not involved in fatty acid biosynthesis, which is carried out by a decarboxylating condensation of acetyl and malonyl esters of acyl carrier proteins. Rather, this activity may produce acetoacetyl-CoA for pathways such as IPP biosynthesis in the absence of sufficient fatty acid oxidation. [Fatty acid and phospholipid metabolism, Other].	4.24471e-150
NZ_CP045480.1\|WP_153033671.1\|6528140_6528680_+\|DUF305-domain-containing-protein	gnl\|CDD\|367619	pfam03713, DUF305, Domain of unknown function (DUF305). Domain found in small family of bacterial secreted proteins with no known function. Also found in Paramecium bursaria chlorella virus 1. This domain is short and found in one or two copies. The domain has a conserved HH motif that may be functionally important. This domain belongs to the ferritin superfamily. It contains two sequence similar repeats each of which is composed of two alpha helices.	4.07692e-35
NZ_CP045480.1\|WP_153033667.1\|6520791_6521403_-\|DUF4178-domain-containing-protein	gnl\|CDD\|379368	pfam13785, DUF4178, Domain of unknown function (DUF4178).	6.12752e-32
NZ_CP045480.1\|WP_040406084.1\|6522051_6522768_+\|response-regulator-transcription-factor	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	2.51418e-57
NZ_CP045480.1\|WP_153033663.1\|6516428_6516983_+\|DUF3000-family-protein	gnl\|CDD\|378665	pfam11452, DUF3000, Protein of unknown function (DUF3000). This is a bacterial family of uncharacterized proteins.	5.46501e-89
NZ_CP045480.1\|WP_153033661.1\|6513819_6515238_-\|protoporphyrinogen-oxidase	gnl\|CDD\|237009	PRK11883, PRK11883, protoporphyrinogen oxidase; Reviewed.	1.40244e-143
NZ_CP045480.1\|WP_153033666.1\|6520332_6520764_-\|DUF4247-domain-containing-protein	gnl\|CDD\|379437	pfam14042, DUF4247, Domain of unknown function (DUF4247). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 143 and 271 amino acids in length.	3.34966e-17
NZ_CP045480.1\|WP_153033668.1\|6522830_6524087_+\|ribonuclease-D	gnl\|CDD\|223426	COG0349, Rnd, Ribonuclease D [Translation, ribosomal structure and biogenesis].	6.35726e-92
NZ_CP045480.1\|WP_153033662.1\|6515240_6516320_-\|uroporphyrinogen-decarboxylase	gnl\|CDD\|234644	PRK00115, hemE, uroporphyrinogen decarboxylase; Validated.	0
NZ_CP045480.1\|WP_153033672.1\|6529995_6532104_+\|3-hydroxyacyl-CoA-dehydrogenase	gnl\|CDD\|236864	PRK11154, fadJ, fatty acid oxidation complex subunit alpha FadJ.	2.65927e-119
NZ_CP045480.1\|WP_153033669.1\|6524951_6527204_+\|chitinase	gnl\|CDD\|119365	cd06548, GH18_chitinase, The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an eight-stranded alpha/beta barrel with a pronounced active-site cleft at the C-terminal end of the beta-barrel.	4.98689e-122
NZ_CP045480.1\|WP_153033660.1\|6513139_6513832_-\|hypothetical-protein	gnl\|CDD\|377705	pfam06778, Chlor_dismutase, Chlorite dismutase. This family contains chlorite dismutase enzymes of bacterial and archaeal origin. This enzyme catalyzes the disproportionation of chlorite into chloride and oxygen. Note that many family members are hypothetical proteins.	9.76922e-101
NZ_CP045480.1\|WP_153037349.1\|6511415_6512687_-\|carnitine-dehydratase	gnl\|CDD\|367110	pfam02515, CoA_transf_3, CoA-transferase family III. CoA-transferases are found in organisms from all lines of descent. Most of these enzymes belong to two well-known enzyme families, but recent work on unusual biochemical pathways of anaerobic bacteria has revealed the existence of a third family of CoA-transferases. The members of this enzyme family differ in sequence and reaction mechanism from CoA-transferases of the other families. Currently known enzymes of the new family are a formyl-CoA: oxalate CoA-transferase, a succinyl-CoA: (R)-benzylsuccinate CoA-transferase, an (E)-cinnamoyl-CoA: (R)-phenyllactate CoA-transferase, and a butyrobetainyl-CoA: (R)-carnitine CoA-transferase. In addition, a large number of proteins of unknown or differently annotated function from Bacteria, Archaea and Eukarya apparently belong to this enzyme family. Properties and reaction mechanisms of the CoA-transferases of family III are described and compared to those of the previously known CoA-transferases.	2.48852e-42
NZ_CP045480.1\|WP_153037350.1\|6524136_6524742_-\|TetR-family-transcriptional-regulator	gnl\|CDD\|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	4.63558e-12
NZ_CP045480.1\|WP_153033670.1\|6527235_6528141_+\|chitin-binding-protein	gnl\|CDD\|376983	pfam03067, LPMO_10, Lytic polysaccharide mono-oxygenase, cellulose-degrading. This domain is found associated with a wide variety of cellulose binding domains. This is a family of two very closely related proteins that together act as both a C1- and a C4-oxidising lytic polysaccharide mono-oxygenase, degrading cellulose. This domain is also found in baculoviral spheroidins and spindolins, protein of unknown function.	2.60937e-56
NZ_CP045480.1\|WP_153033665.1\|6518550_6518973_-\|DUF350-domain-containing-protein	gnl\|CDD\|377187	pfam03994, DUF350, Domain of Unknown Function (DUF350). This domain occurs in a small set of of bacterial proteins. It has two transmembrane regions, and often occurs as tandem repeats. The are no conserved catalytic residues.	9.41234e-09
NZ_CP045480.1\|WP_153033664.1\|6516979_6518554_-\|polyamine-aminopropyltransferase	gnl\|CDD\|235139	PRK03612, PRK03612, polyamine aminopropyltransferase.	0

>NZ_CP045480.1|WP_153033665.1|6518550_6518973_-|DUF350-domain-containing-protein
MSELVLGLLATLAYGAVGTILMALGFALVDLATPGKLRELIWVQGNRNASVLLASGLLGVGVIVTTAIITSDSDLVTGLLSTVVFGLAGLALMSIAFVLLDLATPGKLGEILARPEPHPAVWVSAAVHVAVSAIIAAAIT
>NZ_CP045480.1|WP_153033664.1|6516979_6518554_-|polyamine-aminopropyltransferase
MTTTETETEVAAPRTRLARAAVLLAVFVCAACGLVYELALVALGSYLIGDTVGQASIVLSVMVFAMGVGALLAKPLQRRAEAAFAGIEIALALLGGLSVLLLYAAYAWLSLYVPALVVIALLLGMLIGAEIPLLMVLLQRIRKQDAGSAVADLFAADYVGALLGGLAFPFLLLPVFGQIRGALLVGAVNAIAGLGLVLTVFRKRLRRRTQAVLSVAAVGVTVVLTGTFVFAGQFELSARQALYADPVVHAERTPYQEIVITESVDLSGPADVRFYLNGDLQFSSVDEYRYHEALVHPVLAGPHESVLILGGGDGLGLREVLRYPDVRRVTLVELDPEVVRLARSQPDLLAMNQGAFNDPRVQVVTADAFTWLRENAARYDSIIVDMPDPDSTATAKLYSVEFYALVRRAMADGGRMVVQAGSPYFAPRSYWCVEASLREVGLRSTPYYMSVPSFGDWGFHLATANAEPELRLSPGAPALRALDTESLRAAGVFPVDRRRIPDVPSSSLMQPRVLEYAKDEWRNY
>NZ_CP045480.1|WP_153033663.1|6516428_6516983_+|DUF3000-family-protein
MTHAPDLFREAVAALDSVRSRPEVVLEPMRAPQRLAPWAYALSCEVTGPADVLASGRLVLLHDPDGQEGWNGVLRMVIYVRAELDRELATDPFLPDVGWSWLTDALEHNGAAFSSLGGTVTETSSARFGDIAGPSRTDDLELRASWTPDDASLRPHGEAFVQLMSSVVGLPPVGVSLFEQRQGS
>NZ_CP045480.1|WP_153033662.1|6515240_6516320_-|uroporphyrinogen-decarboxylase
MSSSVSAPATATARRALPDAPFLLAARGERPARLPVWFMRQAGRSLPEYRELRAGTAMLDACFDPEMLAEITLQPVRRHGVDAAILFSDIVVPLKAAGLDIDIVAGTGPVVAGPVRDAAAVAALPELDAEQVVPVAEGIRLLVERLGDTPLIGFAGAPFTLASYLIEGGPSRNHERTKALMHSEPAVWHALAGKLADIALGFLRVQIAAGVDAIQLFDSWAGALSPRDYREFVLPHSAKVFAGVADAGVPRIHFGVGTGELLSDLRDAGPDVVGVDWRVPLDEAVRRLTATRPGSAPVVQGNLDPALLFGSWPVLEAEVRRIAEEGRAAAGHIFNLGHGVLPDTDPEVITRVVELVHSL
>NZ_CP045480.1|WP_153033661.1|6513819_6515238_-|protoporphyrinogen-oxidase
MTTRIAVVGGGVSGLAAAYRLRRLLGADAELTVFESTGAPGGKLRTGTLAGRPFDLGAEAFLARRPEAVALARELGLEVVHPTGARATVRAGGRARRLPPGTMMGVPASADAVSSVLSPEGLAAVAAEAELTPVELPAEDVPLGGLLRSRFGDELVDRLVDPLLGGVYAGGADGLGLRATMPGLAGALDRGVPTLTEAAASLVPASPSSAPVFGTLGSGLGTLIERLVAASGARVRTGTTVRELHRLSGGWRLVLGAAATAHAPEESTVDFDAVLLAVPAPAARRLLDGVAPAASAAYGRVELASMAVIGLALPPGTELPDASGVLVGASERREDGRPFAVKAFTFSARKWAHHGGDEVLLRGSVGRFREPGALHADDDELVRLVLDDLAELTGVRADPVDSVVTRWGGGLPQYGAGHTGLVASIDRAVAELPGLEVAGATLRGVGIPACVATADAAATRLAEFAKMDAWRG
>NZ_CP045480.1|WP_153033660.1|6513139_6513832_-|hypothetical-protein
MARLNYNELNDTIRYTAWSVFRAEPGRLPEDRGPAARETTEFLDGLESKGVVVRGVYDVAGLRADADYLIWWHAEEIEQVQAAYTGFRRTPLGRASVPVWSQVALHRPAEFNRSHIPAFLAGEEPRKYVCVYPFVRSYEWYLLPDDERRKMLADHGKEARDYPDVRANTVASFALGDYEWILAFEADELHRIVDLMRHLRGTEARLHVREEIPFYTGTRVPPAELIQNLP
>NZ_CP045480.1|WP_153033659.1|6512759_6513089_-|hypothetical-protein
MSFPEIDRKQKQMRHDIDDIHELLDHTNKRVDVIDTKVESILEVQEAHGEQLHKIDERLHGIETRLSGHDAQFETLNARLDGQSARLDSQGEQLNQIIELLRGQRPETN
>NZ_CP045480.1|WP_153037349.1|6511415_6512687_-|carnitine-dehydratase
MTVSGDESVLPGPFRVAAAAAASVGVATLAAAELLRLRGIEPPPVEVEIRHAVAAFHSERHLRVDGEVPGELWAPLTGDYLATDGWVRLHCNYPRHVSAVCWGLGAAATREAVTEAVAKRRAREVQEAVIAAGGAAALMRTRQDWLNHPQGAAVAGQPLVELHQTGSAPPKRLFESDRPLGGVRVLELTHVIAGPVAGRVLAAHGADVLHIGAAHLPRIDPLWIDTGLGKRSAFTDLTQDAGRARLRKLLAKADVFVQSFRPGALARWGFSPEELADEFPGLITLDLSAYGPSGPWRNRRGFDSLVQLATGIAAHAGLDRPHPLPAQALDHATGWLAAATVMTALRRAVTDGGGWRGQVALARTAEWLESLGRREITDTGYTADDLLAKLPSPYGELTCVPVPGANPQWTEGTRLPGTDRPSW
>NZ_CP045480.1|WP_153033658.1|6511097_6511445_+|hypothetical-protein
MSRERLAAQQAELLRALLAGGAAPAGFDPGRVEVEVRALRAKRRRIVAYLRPELPQELGDRFVPLFTEYAATHPREEGVRMRQDAENFANWLTARGELKRPRWWQRLPGRAVRAR
>NZ_CP045480.1|WP_153037348.1|6510300_6511101_+|DUF692-family-protein
MPRFGVGIGWRPELDLSVPRLPGVDWVEVVAENLQPGALPASLTALRDRGVPVLPHAVSLSLGGAEELDTRRVEHLAELTAALGAPVASDHVCFVRAGGLDSGHLMPLPRTREALDVLVDNVKLAQSILGVPFALENIAALLEWPDPELSEARFLTELTDRTGCLLIVDVANLYANARNLGSDPVSFLDEIPLDRLAYVHVAGGEEHHGVYHDTHAHAVPPQVLDLLGELRSRVDPPGVLLERDDAYPTDAELAAELAAIRAVVDA
>NZ_CP045480.1|WP_153033666.1|6520332_6520764_-|DUF4247-domain-containing-protein
MKYRLWFVLGGILAVIALIIAVNLLFFGGTSVANFVDNEFDRDTSQDFDDDVRSYTSGEKPSAVSTLIVTDWKPLAQSADNSGIYLRYSSDAVVITPRGTGSTIQVMDVDRAYRRYGGHAGGSWGWTSTHGGDFRGRGPGAGK
>NZ_CP045480.1|WP_153033667.1|6520791_6521403_-|DUF4178-domain-containing-protein
MVDALVVVLLVLILVALVVVGVLLARRGRAKPPAPASTAADPFSSADVDAVRGDPRELAPGALVEIRGESYGVRGTLRLTEDGWSWTEHLLENAAGRRFWLSVEEDPELELVLFTELSDVTVAPGKTIELDGRTYRHQESGTATFTAEGTTGLNSGGTVHYQDYAAGDDARLSLESYGESGKWEVSRGEVLSRYEVRSYPSGD
>NZ_CP045480.1|WP_040406084.1|6522051_6522768_+|response-regulator-transcription-factor
MAAVGLSQAVRSTPAGALPASMVPHPREELFSVLVVDDHPLLREAIAARLAQMGAGTVHEAATVAEARARATATGPCDLAILDLGLPDGSGIELVTELRSHGWPRVVVLASSDDPYAVRSAFQAGAQAYLLKSASPVVVTDGVRRVLEGGVYADPSVAPVLATGTRVAGTDNTPRELSAREVEVLQLVADGQSNKEIGEELSLSALTVKSHLSRIGRKLGTGDRAQMVALAMRAGVIR
>NZ_CP045480.1|WP_153033668.1|6522830_6524087_+|ribonuclease-D
MDTADQDGATSGTPESPAPIPLREPAEGTPGVIADPEELERACARIAEGAGAIAVDTERASGYRYWPKAYLVQLRREGVGSFLVDPIPLSGQLGPLADVLNGAEWVLHAASQDLPCLAELELRPTALFDTELAGRLAGYDRVALGTLVEKLLGYQLEKGHSAADWSRRPLPVDWLNYAALDVELLIPLREKLEAELEAQGKLDWARQEFEAVRTAPPPPPRAEPWRRVSGIHKIRSPRGLAAVREFWQIRDEMARKRDRAPSRVLPDSAIVSAVLADPKTTAELQALPVFSGRVQRKFASTWMRPLQVARTLAKSELPLPAQPTDGPPPPNRWADKDPEAAARLSAARAALNALAEHHRLPVENLLLPELVRRTCWRPPEDLSEAGVAEVLRAGGARPWQIELTAPALAKALTAKPEA
>NZ_CP045480.1|WP_153037350.1|6524136_6524742_-|TetR-family-transcriptional-regulator
MLDAAAELFTTTGYTATTTRAIAELAGLRQASIYYHFPAKEDLLAALLAETVDPSLAVARELLGEFAPAEIRLWALSYSDIRLLGLARHNLGVLCLLPEVKALNLTGFRVARAELKDCYRALIAEAGAEPASLDICTSLAFGLVESVASARRDDPDLDVEAHARHGADAVLRLAGLPGASGSVRAAGLDLLHAAELERSRV
>NZ_CP045480.1|WP_153033669.1|6524951_6527204_+|chitinase
MRHTPRRLLSALLAFLLALTVSAALGRPAAAAGPLTAAFTLTGTTGQYQVTNSGTTAVTGWTINFRLPAGVTATSGQHATVTQNGTEVTLTPAYYLNTLQPGRSTYPYNPTFQLSAAATPTACRVAGANCDGSPDTPPSAPGNVQATVKTTKSVTLTWTASAPGSLPVASYEVFNSSAKAATVTSPTATISGLTPNTDYSFTVVAKDTAGLASPASAPLSVRTNNPSDDTQAPTAPGNLHATGTDAGSVSLAWTASTDNTGVAAYDVYRGTTLAATVTTTSAKISGLTPSTSYSFTVRARDGYDNTSAPSNAITAKTGDIVGGYAKIGYFVQWGIYGRQFFVRNLDTNGAAAKLTHLNYAFGNIDPVNLTCLHGVTKGTSPNPQDPNQGDGAGDAEADYSRPMSAAQSVDGVADTGWEKLRGNYNQLKKLKAKHPNLKVLISLGGWTYSKYFSDVAATDAARKKFVSSCLDIYLKGNLPVYNGAGGPGTAAGIFDGIDLDWEWPGAEGHPGNHVSPADKVNNTLLINEFRKQLDELGAQQGKRYQLTAFTPADPAKIEAGWELGPVANSLDIFNVQGYDFHGAGSDNSWEPNRTGHQGNLYTDPDDPYNFHFSVENAIKPYLDAGVNPRKLTVGLAFYGRGWQGVTDGGKAGEWQQANGAAPGQFAEEAGTRGYSNLVAGVPNCTVHHDEAAVATSCFTGNGGQWWTFDDAWAIGKKTAWIKSKGLLGAMIWEMSGDTGTLMTATDNGLK
>NZ_CP045480.1|WP_153033670.1|6527235_6528141_+|chitin-binding-protein
MNTRRTAAASLAGAAAATLFVALPSPPASAHGTLSNPPSRVYTCKEEGPETPKSGACKAAVAAGGTQPFYDWNEVSLLDAGGRHREIIPDGKLCSAGRAKYRGLDLPRTDWPATKVAPGPLTVTYHATAPHANSNFEFYVTREGWSPGKPLAWADLVPLESFPNQNPSTFTDWTVTLPQRSGRHLLYSIWQRVQGSAEAFYTCSDVDFGGGTSTPAPQDPEPEPQPEPPNPEPEPPQQPEPPQPQPPQSEPPQPGGTWAAGTTYRVGDEVTFDGTTYRCRQAHTTIAGWEPPVVPALWLPV
>NZ_CP045480.1|WP_153033671.1|6528140_6528680_+|DUF305-domain-containing-protein
MRYAFAVLALVLLGACSPSGATESASGEPTPHNAADVGFLQSMVPHHEEGVRIAVLAERSEREEVRLLGGAIEATQVAEIETMSKQLDDWEQPATPPSGHHEHEERPSTAPAELTSLEQATGAEFDRRFLNLMLAHQDDAIQLARQEVLNGQDPATKELAGRIDRSRSAQIEQMLSMLG
>NZ_CP045480.1|WP_153037351.1|6528808_6529999_+|acetyl-CoA-C-acyltransferase
MRNVAFVEGVRTPFGKAGDKGIYAGTRADDLVVKVIRELLRRHPELPPERVDEVAVAATTQTGDQGLTIGRTAALLAGLPKSVPGFAIDRMCAGAMTAVTTTASGIGFGAYDIAIAGGVEHMGRHPMGEGVDPNPRIIADKLVDPTALVMGQTAENVHDRFPEITKQRTDAYAARSQERYADAVKAGKIGPELVPVATRHAELGWGLATEDEPPRPGTTVEQLAGLKTPFRPHGRVTAGNAAGLNDGATGAILAAEEVAEELGLPIGMRLVSYAFAGVEPEVMGIGPVPATEKLLARTGLSISDIGLFEINEAFAVQVLAFLDHFGISEDDPRVNQWGGAIACGHPLASSGVRLMTQLSRQFAERPDVRYGLTTMCIGIGMGGTVIWENPAWEGNK
>NZ_CP045480.1|WP_153033672.1|6529995_6532104_+|3-hydroxyacyl-CoA-dehydrogenase
MISAAEAEAAFPDEVVTRAVTRLITVPGLDGQVALITIDNGHDHARPSTFGPQSLVSLNSAIDAAFAAEPVAIAVTGKPFIFAVGADLSGVEQIAGRDLALQIAQTGHDVFRRLTESKIPTFAFVNGAVMGGGLELALSCHYRTLSENTAAIAFPEVFLGLFPGWGGTQLLPNLIGPDAAVTVTIENALSQNKMLKPAQAAQLGIVDEVFGSADYLEQSLLWLAKVVRGEVTPARREIDRGEEWDRAVARAKSIVDGKTKGASPGANKAVELLELARANDLDRGYAAETEALADVLMTDTLRAGLYSFNLVNKRAKRPAGAPDKSLARPVNKVGIVGAGLMASQLALLFVRRLKVPVVLTDIDQERVDKGVGYVHGEIDKLLAKKRVSPDAANRLKALVSGSLDKAAFADADFVIEAVFEELGVKQQVFAEVEAHVKPEAILATNTSSLSITEMAAKLEHPERVVGFHFFNPVAVLPLLEIVRGEKTDDASLATAFAVGKQLKKSSVLVSDAPAFVVNRLLTRFLGEVLAAVDEGTPFEVADRALDPLGLPMSPLTLLQLVGPPVALHVAETMHRAFPDRFGVSQNLKKFVEAGKSAVWQWDDKGNATVDPEVAALWEQGDRPSTEEQLRERALSVLAEEVRIMLDEGVVAEAQDIDLCLILGAGWPFWLGGITPYLDRSGVSEKVNGKPFLAPGIASVPSA

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Crispr_ID: NZ_CP045480_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045480_5

6519010-6519368

Orphan

Consensus_repeat	Method
GCTGGCCCGGCTGCGATTGCCCCGG	CRISPRCasFinder

5 spacers

The CRISPR arrays of NZ_CP045480_5

>merge|NZ_CP045480|5|6519010-6519368|CRISPRCasFinder
AACGGCCGTGCGGCCACTGCCCCGGCGGCTGCTGAGGCGGATACTGCGGCCACCCCGGCGCCTGCCCACCCTGCTGCCCCGGCTGATATTGGCCGGGTTGCTGGCCTGACTGCTGCTGGCCGGGCTGAGGGCCTGGTTGGTGATGCCCGGGTTGCTGCCCCGGGTGCTGCGGCCCGGGCTGGTGTGGTTGTCCCGAATGCTGCTGCTGCCCCGGCCACGGCTGTTGCCCTGGCTGGTGCTGTCCCGGCTGGTGCCCCGGGTGGTACGGCCCGGACTGCTGGCCCGGCTGCTGGTACCCGGGCTGCGATTGACCCGGCTGGTGCTGTCCAGGCGACTGGCCCGGCGGCGGTTGCTGCCCA

>NZ_CP045480|5|5|6519010-6519368|CRISPRCasFinder
AACGGCCGTGCGGCCACTGCCCCGG	CGGCTGCTGAGGCGGATACTGCGGCCACCCCGGCGCCTGCCCACCCT
GCTGCCCCGGCTGATATTGGCCGGG	TTGCTGGCCTGACTGCTGCTGGCCGGGCTGAGGGCCTGGTTGGTGATGCCCGGGTT
GCTGCCCCGGGTGCTGCGGCCCGGG	CTGGTGTGGTTGTCCCGAATGCTGCTGCTGCCCCGGCCACGGCT
GTTGCCCTGGCTGGTGCTGTCCCGG	CTGGTGCCCCGGGTGGTACGGCCCGGACT
GCTGGCCCGGCTGCTGGTACCCGGG	CTGCGATTGACCCGGCTGGTGCTGTCCAGGCG
ACTGGCCCGGCGGCGGTTGCTGCCCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045480.1\|WP_153037348.1\|6510300_6511101_+\|DUF692-family-protein	unknown	unknown	gnl\|CDD\|377459
NZ_CP045480.1\|WP_153033670.1\|6527235_6528141_+\|chitin-binding-protein	unknown	unknown	gnl\|CDD\|376983
NZ_CP045480.1\|WP_153033658.1\|6511097_6511445_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045480.1\|WP_153033667.1\|6520791_6521403_-\|DUF4178-domain-containing-protein	unknown	unknown	gnl\|CDD\|379368
NZ_CP045480.1\|WP_153033663.1\|6516428_6516983_+\|DUF3000-family-protein	unknown	unknown	gnl\|CDD\|378665
NZ_CP045480.1\|WP_153037351.1\|6528808_6529999_+\|acetyl-CoA-C-acyltransferase	unknown	unknown	gnl\|CDD\|273881
NZ_CP045480.1\|WP_153033661.1\|6513819_6515238_-\|protoporphyrinogen-oxidase	unknown	unknown	gnl\|CDD\|237009
NZ_CP045480.1\|WP_153033666.1\|6520332_6520764_-\|DUF4247-domain-containing-protein	unknown	unknown	gnl\|CDD\|379437
NZ_CP045480.1\|WP_153033668.1\|6522830_6524087_+\|ribonuclease-D	unknown	unknown	gnl\|CDD\|223426
NZ_CP045480.1\|WP_153033662.1\|6515240_6516320_-\|uroporphyrinogen-decarboxylase	unknown	unknown	gnl\|CDD\|234644
NZ_CP045480.1\|WP_153033671.1\|6528140_6528680_+\|DUF305-domain-containing-protein	unknown	unknown	gnl\|CDD\|367619
NZ_CP045480.1\|WP_153033669.1\|6524951_6527204_+\|chitinase	unknown	unknown	gnl\|CDD\|119365
NZ_CP045480.1\|WP_153033660.1\|6513139_6513832_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377705
NZ_CP045480.1\|WP_040406084.1\|6522051_6522768_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225107
NZ_CP045480.1\|WP_153037349.1\|6511415_6512687_-\|carnitine-dehydratase	unknown	unknown	gnl\|CDD\|367110
NZ_CP045480.1\|WP_153033672.1\|6529995_6532104_+\|3-hydroxyacyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|236864
NZ_CP045480.1\|WP_153037350.1\|6524136_6524742_-\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|366102
NZ_CP045480.1\|WP_153033664.1\|6516979_6518554_-\|polyamine-aminopropyltransferase	unknown	unknown	gnl\|CDD\|235139
NZ_CP045480.1\|WP_153033665.1\|6518550_6518973_-\|DUF350-domain-containing-protein	unknown	unknown	gnl\|CDD\|377187
NZ_CP045480.1\|WP_153033659.1\|6512759_6513089_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP045480.1\|WP_153037348.1\|6510300_6511101_+\|DUF692-family-protein	gnl\|CDD\|377459	pfam05114, DUF692, Protein of unknown function (DUF692). This family consists of several uncharacterized bacterial proteins.	1.61452e-108
NZ_CP045480.1\|WP_153037351.1\|6528808_6529999_+\|acetyl-CoA-C-acyltransferase	gnl\|CDD\|273881	TIGR01930, 3-ketoacyl-CoA_thiolase, acetyl-CoA acetyltransferases. This model represents a large family of enzymes which catalyze the thiolysis of a linear fatty acid CoA (or acetoacetyl-CoA) using a second CoA molecule to produce acetyl-CoA and a CoA-ester product two carbons shorter (or, alternatively, the condensation of two molecules of acetyl-CoA to produce acetoacetyl-CoA and CoA). This enzyme is also known as "thiolase", "3-ketoacyl-CoA thiolase", "beta-ketothiolase" and "Fatty oxidation complex beta subunit". When catalyzing the degradative reaction on fatty acids the corresponding EC number is 2.3.1.16. The condensation reaction corresponds to 2.3.1.9. Note that the enzymes which catalyze the condensation are generally not involved in fatty acid biosynthesis, which is carried out by a decarboxylating condensation of acetyl and malonyl esters of acyl carrier proteins. Rather, this activity may produce acetoacetyl-CoA for pathways such as IPP biosynthesis in the absence of sufficient fatty acid oxidation. [Fatty acid and phospholipid metabolism, Other].	4.24471e-150
NZ_CP045480.1\|WP_153033671.1\|6528140_6528680_+\|DUF305-domain-containing-protein	gnl\|CDD\|367619	pfam03713, DUF305, Domain of unknown function (DUF305). Domain found in small family of bacterial secreted proteins with no known function. Also found in Paramecium bursaria chlorella virus 1. This domain is short and found in one or two copies. The domain has a conserved HH motif that may be functionally important. This domain belongs to the ferritin superfamily. It contains two sequence similar repeats each of which is composed of two alpha helices.	4.07692e-35
NZ_CP045480.1\|WP_153033667.1\|6520791_6521403_-\|DUF4178-domain-containing-protein	gnl\|CDD\|379368	pfam13785, DUF4178, Domain of unknown function (DUF4178).	6.12752e-32
NZ_CP045480.1\|WP_040406084.1\|6522051_6522768_+\|response-regulator-transcription-factor	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	2.51418e-57
NZ_CP045480.1\|WP_153033663.1\|6516428_6516983_+\|DUF3000-family-protein	gnl\|CDD\|378665	pfam11452, DUF3000, Protein of unknown function (DUF3000). This is a bacterial family of uncharacterized proteins.	5.46501e-89
NZ_CP045480.1\|WP_153033661.1\|6513819_6515238_-\|protoporphyrinogen-oxidase	gnl\|CDD\|237009	PRK11883, PRK11883, protoporphyrinogen oxidase; Reviewed.	1.40244e-143
NZ_CP045480.1\|WP_153033666.1\|6520332_6520764_-\|DUF4247-domain-containing-protein	gnl\|CDD\|379437	pfam14042, DUF4247, Domain of unknown function (DUF4247). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 143 and 271 amino acids in length.	3.34966e-17
NZ_CP045480.1\|WP_153033668.1\|6522830_6524087_+\|ribonuclease-D	gnl\|CDD\|223426	COG0349, Rnd, Ribonuclease D [Translation, ribosomal structure and biogenesis].	6.35726e-92
NZ_CP045480.1\|WP_153033662.1\|6515240_6516320_-\|uroporphyrinogen-decarboxylase	gnl\|CDD\|234644	PRK00115, hemE, uroporphyrinogen decarboxylase; Validated.	0
NZ_CP045480.1\|WP_153033672.1\|6529995_6532104_+\|3-hydroxyacyl-CoA-dehydrogenase	gnl\|CDD\|236864	PRK11154, fadJ, fatty acid oxidation complex subunit alpha FadJ.	2.65927e-119
NZ_CP045480.1\|WP_153033669.1\|6524951_6527204_+\|chitinase	gnl\|CDD\|119365	cd06548, GH18_chitinase, The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an eight-stranded alpha/beta barrel with a pronounced active-site cleft at the C-terminal end of the beta-barrel.	4.98689e-122
NZ_CP045480.1\|WP_153033660.1\|6513139_6513832_-\|hypothetical-protein	gnl\|CDD\|377705	pfam06778, Chlor_dismutase, Chlorite dismutase. This family contains chlorite dismutase enzymes of bacterial and archaeal origin. This enzyme catalyzes the disproportionation of chlorite into chloride and oxygen. Note that many family members are hypothetical proteins.	9.76922e-101
NZ_CP045480.1\|WP_153037349.1\|6511415_6512687_-\|carnitine-dehydratase	gnl\|CDD\|367110	pfam02515, CoA_transf_3, CoA-transferase family III. CoA-transferases are found in organisms from all lines of descent. Most of these enzymes belong to two well-known enzyme families, but recent work on unusual biochemical pathways of anaerobic bacteria has revealed the existence of a third family of CoA-transferases. The members of this enzyme family differ in sequence and reaction mechanism from CoA-transferases of the other families. Currently known enzymes of the new family are a formyl-CoA: oxalate CoA-transferase, a succinyl-CoA: (R)-benzylsuccinate CoA-transferase, an (E)-cinnamoyl-CoA: (R)-phenyllactate CoA-transferase, and a butyrobetainyl-CoA: (R)-carnitine CoA-transferase. In addition, a large number of proteins of unknown or differently annotated function from Bacteria, Archaea and Eukarya apparently belong to this enzyme family. Properties and reaction mechanisms of the CoA-transferases of family III are described and compared to those of the previously known CoA-transferases.	2.48852e-42
NZ_CP045480.1\|WP_153037350.1\|6524136_6524742_-\|TetR-family-transcriptional-regulator	gnl\|CDD\|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	4.63558e-12
NZ_CP045480.1\|WP_153033670.1\|6527235_6528141_+\|chitin-binding-protein	gnl\|CDD\|376983	pfam03067, LPMO_10, Lytic polysaccharide mono-oxygenase, cellulose-degrading. This domain is found associated with a wide variety of cellulose binding domains. This is a family of two very closely related proteins that together act as both a C1- and a C4-oxidising lytic polysaccharide mono-oxygenase, degrading cellulose. This domain is also found in baculoviral spheroidins and spindolins, protein of unknown function.	2.60937e-56
NZ_CP045480.1\|WP_153033665.1\|6518550_6518973_-\|DUF350-domain-containing-protein	gnl\|CDD\|377187	pfam03994, DUF350, Domain of Unknown Function (DUF350). This domain occurs in a small set of of bacterial proteins. It has two transmembrane regions, and often occurs as tandem repeats. The are no conserved catalytic residues.	9.41234e-09
NZ_CP045480.1\|WP_153033664.1\|6516979_6518554_-\|polyamine-aminopropyltransferase	gnl\|CDD\|235139	PRK03612, PRK03612, polyamine aminopropyltransferase.	0

>NZ_CP045480.1|WP_153033665.1|6518550_6518973_-|DUF350-domain-containing-protein
MSELVLGLLATLAYGAVGTILMALGFALVDLATPGKLRELIWVQGNRNASVLLASGLLGVGVIVTTAIITSDSDLVTGLLSTVVFGLAGLALMSIAFVLLDLATPGKLGEILARPEPHPAVWVSAAVHVAVSAIIAAAIT
>NZ_CP045480.1|WP_153033664.1|6516979_6518554_-|polyamine-aminopropyltransferase
MTTTETETEVAAPRTRLARAAVLLAVFVCAACGLVYELALVALGSYLIGDTVGQASIVLSVMVFAMGVGALLAKPLQRRAEAAFAGIEIALALLGGLSVLLLYAAYAWLSLYVPALVVIALLLGMLIGAEIPLLMVLLQRIRKQDAGSAVADLFAADYVGALLGGLAFPFLLLPVFGQIRGALLVGAVNAIAGLGLVLTVFRKRLRRRTQAVLSVAAVGVTVVLTGTFVFAGQFELSARQALYADPVVHAERTPYQEIVITESVDLSGPADVRFYLNGDLQFSSVDEYRYHEALVHPVLAGPHESVLILGGGDGLGLREVLRYPDVRRVTLVELDPEVVRLARSQPDLLAMNQGAFNDPRVQVVTADAFTWLRENAARYDSIIVDMPDPDSTATAKLYSVEFYALVRRAMADGGRMVVQAGSPYFAPRSYWCVEASLREVGLRSTPYYMSVPSFGDWGFHLATANAEPELRLSPGAPALRALDTESLRAAGVFPVDRRRIPDVPSSSLMQPRVLEYAKDEWRNY
>NZ_CP045480.1|WP_153033663.1|6516428_6516983_+|DUF3000-family-protein
MTHAPDLFREAVAALDSVRSRPEVVLEPMRAPQRLAPWAYALSCEVTGPADVLASGRLVLLHDPDGQEGWNGVLRMVIYVRAELDRELATDPFLPDVGWSWLTDALEHNGAAFSSLGGTVTETSSARFGDIAGPSRTDDLELRASWTPDDASLRPHGEAFVQLMSSVVGLPPVGVSLFEQRQGS
>NZ_CP045480.1|WP_153033662.1|6515240_6516320_-|uroporphyrinogen-decarboxylase
MSSSVSAPATATARRALPDAPFLLAARGERPARLPVWFMRQAGRSLPEYRELRAGTAMLDACFDPEMLAEITLQPVRRHGVDAAILFSDIVVPLKAAGLDIDIVAGTGPVVAGPVRDAAAVAALPELDAEQVVPVAEGIRLLVERLGDTPLIGFAGAPFTLASYLIEGGPSRNHERTKALMHSEPAVWHALAGKLADIALGFLRVQIAAGVDAIQLFDSWAGALSPRDYREFVLPHSAKVFAGVADAGVPRIHFGVGTGELLSDLRDAGPDVVGVDWRVPLDEAVRRLTATRPGSAPVVQGNLDPALLFGSWPVLEAEVRRIAEEGRAAAGHIFNLGHGVLPDTDPEVITRVVELVHSL
>NZ_CP045480.1|WP_153033661.1|6513819_6515238_-|protoporphyrinogen-oxidase
MTTRIAVVGGGVSGLAAAYRLRRLLGADAELTVFESTGAPGGKLRTGTLAGRPFDLGAEAFLARRPEAVALARELGLEVVHPTGARATVRAGGRARRLPPGTMMGVPASADAVSSVLSPEGLAAVAAEAELTPVELPAEDVPLGGLLRSRFGDELVDRLVDPLLGGVYAGGADGLGLRATMPGLAGALDRGVPTLTEAAASLVPASPSSAPVFGTLGSGLGTLIERLVAASGARVRTGTTVRELHRLSGGWRLVLGAAATAHAPEESTVDFDAVLLAVPAPAARRLLDGVAPAASAAYGRVELASMAVIGLALPPGTELPDASGVLVGASERREDGRPFAVKAFTFSARKWAHHGGDEVLLRGSVGRFREPGALHADDDELVRLVLDDLAELTGVRADPVDSVVTRWGGGLPQYGAGHTGLVASIDRAVAELPGLEVAGATLRGVGIPACVATADAAATRLAEFAKMDAWRG
>NZ_CP045480.1|WP_153033660.1|6513139_6513832_-|hypothetical-protein
MARLNYNELNDTIRYTAWSVFRAEPGRLPEDRGPAARETTEFLDGLESKGVVVRGVYDVAGLRADADYLIWWHAEEIEQVQAAYTGFRRTPLGRASVPVWSQVALHRPAEFNRSHIPAFLAGEEPRKYVCVYPFVRSYEWYLLPDDERRKMLADHGKEARDYPDVRANTVASFALGDYEWILAFEADELHRIVDLMRHLRGTEARLHVREEIPFYTGTRVPPAELIQNLP
>NZ_CP045480.1|WP_153033659.1|6512759_6513089_-|hypothetical-protein
MSFPEIDRKQKQMRHDIDDIHELLDHTNKRVDVIDTKVESILEVQEAHGEQLHKIDERLHGIETRLSGHDAQFETLNARLDGQSARLDSQGEQLNQIIELLRGQRPETN
>NZ_CP045480.1|WP_153037349.1|6511415_6512687_-|carnitine-dehydratase
MTVSGDESVLPGPFRVAAAAAASVGVATLAAAELLRLRGIEPPPVEVEIRHAVAAFHSERHLRVDGEVPGELWAPLTGDYLATDGWVRLHCNYPRHVSAVCWGLGAAATREAVTEAVAKRRAREVQEAVIAAGGAAALMRTRQDWLNHPQGAAVAGQPLVELHQTGSAPPKRLFESDRPLGGVRVLELTHVIAGPVAGRVLAAHGADVLHIGAAHLPRIDPLWIDTGLGKRSAFTDLTQDAGRARLRKLLAKADVFVQSFRPGALARWGFSPEELADEFPGLITLDLSAYGPSGPWRNRRGFDSLVQLATGIAAHAGLDRPHPLPAQALDHATGWLAAATVMTALRRAVTDGGGWRGQVALARTAEWLESLGRREITDTGYTADDLLAKLPSPYGELTCVPVPGANPQWTEGTRLPGTDRPSW
>NZ_CP045480.1|WP_153033658.1|6511097_6511445_+|hypothetical-protein
MSRERLAAQQAELLRALLAGGAAPAGFDPGRVEVEVRALRAKRRRIVAYLRPELPQELGDRFVPLFTEYAATHPREEGVRMRQDAENFANWLTARGELKRPRWWQRLPGRAVRAR
>NZ_CP045480.1|WP_153037348.1|6510300_6511101_+|DUF692-family-protein
MPRFGVGIGWRPELDLSVPRLPGVDWVEVVAENLQPGALPASLTALRDRGVPVLPHAVSLSLGGAEELDTRRVEHLAELTAALGAPVASDHVCFVRAGGLDSGHLMPLPRTREALDVLVDNVKLAQSILGVPFALENIAALLEWPDPELSEARFLTELTDRTGCLLIVDVANLYANARNLGSDPVSFLDEIPLDRLAYVHVAGGEEHHGVYHDTHAHAVPPQVLDLLGELRSRVDPPGVLLERDDAYPTDAELAAELAAIRAVVDA
>NZ_CP045480.1|WP_153033666.1|6520332_6520764_-|DUF4247-domain-containing-protein
MKYRLWFVLGGILAVIALIIAVNLLFFGGTSVANFVDNEFDRDTSQDFDDDVRSYTSGEKPSAVSTLIVTDWKPLAQSADNSGIYLRYSSDAVVITPRGTGSTIQVMDVDRAYRRYGGHAGGSWGWTSTHGGDFRGRGPGAGK
>NZ_CP045480.1|WP_153033667.1|6520791_6521403_-|DUF4178-domain-containing-protein
MVDALVVVLLVLILVALVVVGVLLARRGRAKPPAPASTAADPFSSADVDAVRGDPRELAPGALVEIRGESYGVRGTLRLTEDGWSWTEHLLENAAGRRFWLSVEEDPELELVLFTELSDVTVAPGKTIELDGRTYRHQESGTATFTAEGTTGLNSGGTVHYQDYAAGDDARLSLESYGESGKWEVSRGEVLSRYEVRSYPSGD
>NZ_CP045480.1|WP_040406084.1|6522051_6522768_+|response-regulator-transcription-factor
MAAVGLSQAVRSTPAGALPASMVPHPREELFSVLVVDDHPLLREAIAARLAQMGAGTVHEAATVAEARARATATGPCDLAILDLGLPDGSGIELVTELRSHGWPRVVVLASSDDPYAVRSAFQAGAQAYLLKSASPVVVTDGVRRVLEGGVYADPSVAPVLATGTRVAGTDNTPRELSAREVEVLQLVADGQSNKEIGEELSLSALTVKSHLSRIGRKLGTGDRAQMVALAMRAGVIR
>NZ_CP045480.1|WP_153033668.1|6522830_6524087_+|ribonuclease-D
MDTADQDGATSGTPESPAPIPLREPAEGTPGVIADPEELERACARIAEGAGAIAVDTERASGYRYWPKAYLVQLRREGVGSFLVDPIPLSGQLGPLADVLNGAEWVLHAASQDLPCLAELELRPTALFDTELAGRLAGYDRVALGTLVEKLLGYQLEKGHSAADWSRRPLPVDWLNYAALDVELLIPLREKLEAELEAQGKLDWARQEFEAVRTAPPPPPRAEPWRRVSGIHKIRSPRGLAAVREFWQIRDEMARKRDRAPSRVLPDSAIVSAVLADPKTTAELQALPVFSGRVQRKFASTWMRPLQVARTLAKSELPLPAQPTDGPPPPNRWADKDPEAAARLSAARAALNALAEHHRLPVENLLLPELVRRTCWRPPEDLSEAGVAEVLRAGGARPWQIELTAPALAKALTAKPEA
>NZ_CP045480.1|WP_153037350.1|6524136_6524742_-|TetR-family-transcriptional-regulator
MLDAAAELFTTTGYTATTTRAIAELAGLRQASIYYHFPAKEDLLAALLAETVDPSLAVARELLGEFAPAEIRLWALSYSDIRLLGLARHNLGVLCLLPEVKALNLTGFRVARAELKDCYRALIAEAGAEPASLDICTSLAFGLVESVASARRDDPDLDVEAHARHGADAVLRLAGLPGASGSVRAAGLDLLHAAELERSRV
>NZ_CP045480.1|WP_153033669.1|6524951_6527204_+|chitinase
MRHTPRRLLSALLAFLLALTVSAALGRPAAAAGPLTAAFTLTGTTGQYQVTNSGTTAVTGWTINFRLPAGVTATSGQHATVTQNGTEVTLTPAYYLNTLQPGRSTYPYNPTFQLSAAATPTACRVAGANCDGSPDTPPSAPGNVQATVKTTKSVTLTWTASAPGSLPVASYEVFNSSAKAATVTSPTATISGLTPNTDYSFTVVAKDTAGLASPASAPLSVRTNNPSDDTQAPTAPGNLHATGTDAGSVSLAWTASTDNTGVAAYDVYRGTTLAATVTTTSAKISGLTPSTSYSFTVRARDGYDNTSAPSNAITAKTGDIVGGYAKIGYFVQWGIYGRQFFVRNLDTNGAAAKLTHLNYAFGNIDPVNLTCLHGVTKGTSPNPQDPNQGDGAGDAEADYSRPMSAAQSVDGVADTGWEKLRGNYNQLKKLKAKHPNLKVLISLGGWTYSKYFSDVAATDAARKKFVSSCLDIYLKGNLPVYNGAGGPGTAAGIFDGIDLDWEWPGAEGHPGNHVSPADKVNNTLLINEFRKQLDELGAQQGKRYQLTAFTPADPAKIEAGWELGPVANSLDIFNVQGYDFHGAGSDNSWEPNRTGHQGNLYTDPDDPYNFHFSVENAIKPYLDAGVNPRKLTVGLAFYGRGWQGVTDGGKAGEWQQANGAAPGQFAEEAGTRGYSNLVAGVPNCTVHHDEAAVATSCFTGNGGQWWTFDDAWAIGKKTAWIKSKGLLGAMIWEMSGDTGTLMTATDNGLK
>NZ_CP045480.1|WP_153033670.1|6527235_6528141_+|chitin-binding-protein
MNTRRTAAASLAGAAAATLFVALPSPPASAHGTLSNPPSRVYTCKEEGPETPKSGACKAAVAAGGTQPFYDWNEVSLLDAGGRHREIIPDGKLCSAGRAKYRGLDLPRTDWPATKVAPGPLTVTYHATAPHANSNFEFYVTREGWSPGKPLAWADLVPLESFPNQNPSTFTDWTVTLPQRSGRHLLYSIWQRVQGSAEAFYTCSDVDFGGGTSTPAPQDPEPEPQPEPPNPEPEPPQQPEPPQPQPPQSEPPQPGGTWAAGTTYRVGDEVTFDGTTYRCRQAHTTIAGWEPPVVPALWLPV
>NZ_CP045480.1|WP_153033671.1|6528140_6528680_+|DUF305-domain-containing-protein
MRYAFAVLALVLLGACSPSGATESASGEPTPHNAADVGFLQSMVPHHEEGVRIAVLAERSEREEVRLLGGAIEATQVAEIETMSKQLDDWEQPATPPSGHHEHEERPSTAPAELTSLEQATGAEFDRRFLNLMLAHQDDAIQLARQEVLNGQDPATKELAGRIDRSRSAQIEQMLSMLG
>NZ_CP045480.1|WP_153037351.1|6528808_6529999_+|acetyl-CoA-C-acyltransferase
MRNVAFVEGVRTPFGKAGDKGIYAGTRADDLVVKVIRELLRRHPELPPERVDEVAVAATTQTGDQGLTIGRTAALLAGLPKSVPGFAIDRMCAGAMTAVTTTASGIGFGAYDIAIAGGVEHMGRHPMGEGVDPNPRIIADKLVDPTALVMGQTAENVHDRFPEITKQRTDAYAARSQERYADAVKAGKIGPELVPVATRHAELGWGLATEDEPPRPGTTVEQLAGLKTPFRPHGRVTAGNAAGLNDGATGAILAAEEVAEELGLPIGMRLVSYAFAGVEPEVMGIGPVPATEKLLARTGLSISDIGLFEINEAFAVQVLAFLDHFGISEDDPRVNQWGGAIACGHPLASSGVRLMTQLSRQFAERPDVRYGLTTMCIGIGMGGTVIWENPAWEGNK
>NZ_CP045480.1|WP_153033672.1|6529995_6532104_+|3-hydroxyacyl-CoA-dehydrogenase
MISAAEAEAAFPDEVVTRAVTRLITVPGLDGQVALITIDNGHDHARPSTFGPQSLVSLNSAIDAAFAAEPVAIAVTGKPFIFAVGADLSGVEQIAGRDLALQIAQTGHDVFRRLTESKIPTFAFVNGAVMGGGLELALSCHYRTLSENTAAIAFPEVFLGLFPGWGGTQLLPNLIGPDAAVTVTIENALSQNKMLKPAQAAQLGIVDEVFGSADYLEQSLLWLAKVVRGEVTPARREIDRGEEWDRAVARAKSIVDGKTKGASPGANKAVELLELARANDLDRGYAAETEALADVLMTDTLRAGLYSFNLVNKRAKRPAGAPDKSLARPVNKVGIVGAGLMASQLALLFVRRLKVPVVLTDIDQERVDKGVGYVHGEIDKLLAKKRVSPDAANRLKALVSGSLDKAAFADADFVIEAVFEELGVKQQVFAEVEAHVKPEAILATNTSSLSITEMAAKLEHPERVVGFHFFNPVAVLPLLEIVRGEKTDDASLATAFAVGKQLKKSSVLVSDAPAFVVNRLLTRFLGEVLAAVDEGTPFEVADRALDPLGLPMSPLTLLQLVGPPVALHVAETMHRAFPDRFGVSQNLKKFVEAGKSAVWQWDDKGNATVDPEVAALWEQGDRPSTEEQLRERALSVLAEEVRIMLDEGVVAEAQDIDLCLILGAGWPFWLGGITPYLDRSGVSEKVNGKPFLAPGIASVPSA

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Crispr_ID: NZ_CP045480_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045480_7

7238820-7238922

Orphan

Consensus_repeat	Method
CGCGCAGGCGAAACCGGCGCCACGTCAG	CRISPRCasFinder

1 spacers

WYL

The CRISPR arrays of NZ_CP045480_7

>merge|NZ_CP045480|7|7238820-7238922|CRISPRCasFinder
CGCGCAGGCGAAACCGGCGCCACGTCAGCGAACCCGGCGGGCAGCCCCAGCCGCGTCAGCCGACCGGCAGGCTGCCGCGCAGGCGAAACCGGCGCCGCGTCAG

>NZ_CP045480|7|7|7238820-7238922|CRISPRCasFinder
CGCGCAGGCGAAACCGGCGCCACGTCAG	CGAACCCGGCGGGCAGCCCCAGCCGCGTCAGCCGACCGGCAGGCTGC
CGCGCAGGCGAAACCGGCGCCGCGTCAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045480.1\|WP_153034215.1\|7231934_7232417_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045480.1\|WP_153037423.1\|7246265_7247168_-\|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|225253
NZ_CP045480.1\|WP_153034225.1\|7239914_7240268_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319898
NZ_CP045480.1\|WP_153034228.1\|7243602_7244403_+\|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|225052
NZ_CP045480.1\|WP_153034214.1\|7229712_7230690_+\|serine-hydrolase	unknown	unknown	gnl\|CDD\|365903
NZ_CP045480.1\|WP_153037422.1\|7243198_7243468_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|224647
NZ_CP045480.1\|WP_153034230.1\|7244866_7245514_-\|deaminase	unknown	unknown	gnl\|CDD\|223340
NZ_CP045480.1\|WP_153034218.1\|7234500_7235277_-\|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|238141
NZ_CP045480.1\|WP_153034222.1\|7238216_7238807_+\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379883
NZ_CP045480.1\|WP_153037421.1\|7230780_7231938_+\|acyltransferase-family-protein	unknown	unknown	gnl\|CDD\|224748
NZ_CP045480.1\|WP_153034231.1\|7245666_7246269_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045480.1\|WP_153034219.1\|7235310_7235754_-\|SRPBCC-family-protein	unknown	unknown	gnl\|CDD\|176863
NZ_CP045480.1\|WP_153034227.1\|7242298_7243123_-\|NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224995
NZ_CP045480.1\|WP_153034226.1\|7240322_7242236_-\|prolyl-oligopeptidase-family-serine-peptidase	unknown	unknown	gnl\|CDD\|224423
NZ_CP045480.1\|WP_153034229.1\|7244408_7244861_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|372667
NZ_CP045480.1\|WP_153034221.1\|7236759_7238220_+\|oxygenase	unknown	unknown	gnl\|CDD\|235728
NZ_CP045480.1\|WP_153034220.1\|7235814_7236687_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|225117
NZ_CP045480.1\|WP_153034224.1\|7239324_7239906_+\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|132427
NZ_CP045480.1\|WP_153034216.1\|7232413_7233793_-\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|223715
NZ_CP045480.1\|WP_153034217.1\|7233789_7234476_-\|response-regulator	unknown	unknown	gnl\|CDD\|223816

Protein	Function_ID	Function_description	E-value
NZ_CP045480.1\|WP_153037423.1\|7246265_7247168_-\|WYL-domain-containing-protein	gnl\|CDD\|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	4.44716e-45
NZ_CP045480.1\|WP_153034225.1\|7239914_7240268_-\|VOC-family-protein	gnl\|CDD\|319898	cd06587, VOC, vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). Type I extradiol dioxygenases catalyze the incorporation of both atoms of molecular oxygen into aromatic substrates, which results in the cleavage of aromatic rings. They are key enzymes in the degradation of aromatic compounds. Type I extradiol dioxygenases include class I and class II enzymes. Class I and II enzymes show sequence similarity; the two-domain class II enzymes evolved from a class I enzyme through gene duplication. Glyoxylase I catalyzes the glutathione-dependent inactivation of toxic methylglyoxal, requiring zinc or nickel ions for activity. The antibiotic resistance proteins in this family use a variety of mechanisms to block the function of antibiotics. Bleomycin resistance protein (BLMA) sequesters bleomycin's activity by directly binding to it. Whereas, three types of fosfomycin resistance proteins employ different mechanisms to render fosfomycin inactive by modifying the fosfomycin molecule. Although the proteins in this superfamily are functionally distinct, their structures are similar. The difference among the three dimensional structures of the three types of proteins in this superfamily is interesting from an evolutionary perspective. Both glyoxalase I and BLMA show domain swapping between subunits. However, there is no domain swapping for type 1 extradiol dioxygenases.	4.91116e-05
NZ_CP045480.1\|WP_153034228.1\|7243602_7244403_+\|LLM-class-flavin-dependent-oxidoreductase	gnl\|CDD\|225052	COG2141, COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Energy production and conversion].	1.2236e-38
NZ_CP045480.1\|WP_153034214.1\|7229712_7230690_+\|serine-hydrolase	gnl\|CDD\|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	3.16353e-30
NZ_CP045480.1\|WP_153037422.1\|7243198_7243468_-\|transcriptional-regulator	gnl\|CDD\|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	8.28852e-29
NZ_CP045480.1\|WP_153034230.1\|7244866_7245514_-\|deaminase	gnl\|CDD\|223340	COG0262, FolA, Dihydrofolate reductase [Coenzyme metabolism].	2.31155e-12
NZ_CP045480.1\|WP_153034218.1\|7234500_7235277_-\|SGNH/GDSL-hydrolase-family-protein	gnl\|CDD\|238141	cd00229, SGNH_hydrolase, SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the typical Ser-His-Asp(Glu) triad from other serine hydrolases, but may lack the carboxlic acid.	6.10557e-08
NZ_CP045480.1\|WP_153034222.1\|7238216_7238807_+\|TetR-family-transcriptional-regulator	gnl\|CDD\|379883	pfam16859, TetR_C_11, Bacterial transcriptional repressor C-terminal. This family of bacterial transcriptional repressors is characterized by the short approximately 50 amino acid stretch of residues constituting the helix-turn-helix DNA binding motif, around the YRFhY motif. The target proteins that are repressed are involved in the transcriptional control of multi-drug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. Another target protein is BetI, an osmoprotectant which controls the choline-glycine betaine pathway in E.coli.	1.99706e-15
NZ_CP045480.1\|WP_153037421.1\|7230780_7231938_+\|acyltransferase-family-protein	gnl\|CDD\|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	3.19714e-44
NZ_CP045480.1\|WP_153034219.1\|7235310_7235754_-\|SRPBCC-family-protein	gnl\|CDD\|176863	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins. The PYR/PYL/RCAR-like family belongs to the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket. PYR/PYL/RCAR plant proteins are receptors involved in signal transduction. They bind abscisic acid (ABA) and mediate its signaling. ABA is a vital plant hormone, which regulates plant growth, development, and response to environmental stresses. Upon binding ABA, these plant proteins interact with a type 2C protein phosphatase (PP2C), such as ABI1 and ABI2, and inhibit their activity. When ABA is bound, a loop (designated the gate/CL2 loop) closes over the ligand binding pocket, resulting in the weakening of the inactive PYL dimer and facilitating type 2C protein phosphatase binding. In the ABA:PYL1:ABI1 complex, the gate blocks substrate access to the phosphatase active site. A conserved Trp from PP2C inserts into PYL to lock the receptor in a closed formation. This group also contains Methylobacterium extorquens AM1 MxaD. The mxaD gene is located within the mxaFJGIR(S)ACKLDEHB cluster which encodes proteins involved in methanol oxidation. MxaD may participate in the periplasmic electron transport chain for oxidation of methanol. Mutants lacking MxaD exhibit a reduced growth on methanol, and a lower rate of respiration with methanol.	1.37828e-12
NZ_CP045480.1\|WP_153034227.1\|7242298_7243123_-\|NAD(P)-dependent-oxidoreductase	gnl\|CDD\|224995	COG2084, MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism].	3.05562e-25
NZ_CP045480.1\|WP_153034226.1\|7240322_7242236_-\|prolyl-oligopeptidase-family-serine-peptidase	gnl\|CDD\|224423	COG1506, DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism].	8.65835e-87
NZ_CP045480.1\|WP_153034229.1\|7244408_7244861_-\|VOC-family-protein	gnl\|CDD\|372667	pfam13669, Glyoxalase_4, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.	3.03864e-12
NZ_CP045480.1\|WP_153034221.1\|7236759_7238220_+\|oxygenase	gnl\|CDD\|235728	PRK06184, PRK06184, hypothetical protein; Provisional.	2.4676e-87
NZ_CP045480.1\|WP_153034220.1\|7235814_7236687_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	5.21636e-29
NZ_CP045480.1\|WP_153034224.1\|7239324_7239906_+\|TetR-family-transcriptional-regulator	gnl\|CDD\|132427	TIGR03384, betaine_BetI, transcriptional repressor BetI. BetI is a DNA-binding transcriptional repressor of the bet (betaine) regulon. In sequence, it is related to TetR (pfam00440). Choline, through BetI, induces the expression of the betaine biosynthesis genes betA and betB by derepression. The choline porter gene betT is also part of this regulon in Escherichia coli. Note that a different transcriptional regulator, ArcA, controls the expression of bet regulon genes in response to oxygen, as BetA is an oxygen-dependent enzyme. [Regulatory functions, DNA interactions].	3.52314e-12
NZ_CP045480.1\|WP_153034216.1\|7232413_7233793_-\|HAMP-domain-containing-protein	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	4.81664e-48
NZ_CP045480.1\|WP_153034217.1\|7233789_7234476_-\|response-regulator	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	2.1901e-82

>NZ_CP045480.1|WP_153034222.1|7238216_7238807_+|TetR-family-transcriptional-regulator
MNRGRPRDPGTDTAILRAAAEVFVERGVEGASIEQIAKRAGVGKVTVYRRWSTKEELIAQSVEALLADQVSHPPAELIATSSPYELVENAIDSTAETAASPEFRALAARVLGSAVSHPELMAVYWEHYIRPRRDLTRALLRRAQEEGTVPGDADLDVLTDMIAGAVTYRALQPNPPDAAGMRTYLRAVFRQAGLLR
>NZ_CP045480.1|WP_153034221.1|7236759_7238220_+|oxygenase
MTVLVTGAGPTGLALACALRLHGVEVRVLDRATGPAETSRANFLHARGSEVLARLGALGELPRESIPAMRITTYAGARPIMRIRFGDPGLRTAAPPMVVSQARVEAALRARLAELGVEPEWGTEVTGAGQDGDGVQVRLGDGGHLTASWLVGCDGSGSAVRRLAGIGFPGAKLSERFLLADLDIDWDLDRDGTSGWVHPDGLFAAMPMPGGSWRLFSYDPDGGAERPEPTEIVDRLRQHLARRTGRTATFGHCTWASVFSVHRRLADTYRRGRIFLAGDAAHVHAPFGGQGMPTGMGDAENLAWKLAMVIDGQAAPELLDTYEAERRPLAENVLRGTALATRVNIADSAAGRFLRDKVLIKLGGLPWVQRKATYTASQLWVSYRKGPLGGRRPLGDRIADLDCVREDASRTTLHAELGGTWALLLPASGGDRVAEEAREGLGKRVVVLRRTDEGQAPALVRPDGHLAWRGETGLGDWLAGALGRAG
>NZ_CP045480.1|WP_153034220.1|7235814_7236687_-|helix-turn-helix-domain-containing-protein
MFESADFDLAPYAEVDLPAQVRRTYCSWSDAGWRSLLVQCFDHAPEAEPFPMPAVADLHLVLCVAGDVEMRTRADGKPVRRRWLPGYFELMVPGLASVRDYRTTSALRTIQVTVPSATVERAAAGLGDREPDFPALAAITGDPMVEQLVRALPPAGGADDLYAESAAAFLVAHLLTKGRHERLPGPEHAAVSRAAALMRERLAEPLTVAEIAAEAHLSVYHFIRVFRAATGETPHRFLTRLRIERARRLLSDTDLTIAQIADRCGFASPGALSSAFLGQVGVRPSVYRRN
>NZ_CP045480.1|WP_153034219.1|7235310_7235754_-|SRPBCC-family-protein
MRKYDATAATAAPPAVVWRLLVDARTWPVWSAVDELVLDRSSGLDPDGHDPVGAVRAFRTGRTVTGERVTGLVEEKQLTYEDAFNSAIHDYRAVVDLTATPDGGTFIHWHGTYSARKGLGWLMQGVMRRVMQRMADGLAAHAAAQPR
>NZ_CP045480.1|WP_153034218.1|7234500_7235277_-|SGNH/GDSL-hydrolase-family-protein
MASGHGPGSVVPMTKRRKALAAVFAVLAVAACSPAEPAAAPVAPPSKFLWMGDSVAEGLAGPLAAAARAGGSSMESIASTGGGNVSGIPELTGSTWDQLTAKLGSFDPDVVAYQVSTYDWGTEQEQLAAYEKLLATVTGAGATLVFVTMPPIRADEFYAGHMEELQRTGGLARRVADGSGGKAVVLDSAAVWGPEYRMDRDGKRDRSPDGIHTCPQGAARFAAWLMGELAARFPGFTPAAPESWANSGWAGGPAFRDC
>NZ_CP045480.1|WP_153034217.1|7233789_7234476_-|response-regulator
MAVILLIEDDPLVSRGLQLALTRYGNTVTTAATGEDGLRACHETAPELVVLDVMLPDLDGFEVCRRLRARGPVPIIMLTARGDDFDVVAGLAAGADDYVTKPVRPAVLDARIKAVLRRGGPRDSDRSNGAQTHGELEIDAAGAVVRKRGQPVALTPIELRTLLALSAAPGRVFTRQQLLEQVWEHDYLGDSRLVDNCVQRLRAKIEDVPAEPVYVQTVRGFGYRFGPV
>NZ_CP045480.1|WP_153034216.1|7232413_7233793_-|HAMP-domain-containing-protein
MRRLFRPRGLRVRLVLAFVLVAVAGAAAAAWAGAASAGASLVGAAERRHTEDLVHRIEAVAPDLNLPPDQEMLDRVRASIGEHTQVTYQGRSSGELPLITGELRAAARDRLVFQRVDTGEGPRLLIGTPIVTTGLDLRRTPSGIEVYAVRDLSDVAGQVDGLVGTAALTSAVALPLAVLLALVAAGGVLRPVRRVRDTAVALAGGDLSARISTGGADELEDLGETVNRMADSLQEVLTEQRRFVADVSHELRTPLTTLTAVVEVLAESADDRRPMARESAELAVAETERLVALVEDLMEVSRFDAGMARLRTEPVEVPDAIRDCLRARGWLDDVQLDLPEPVSATLDRRRLDVIVANLVGNALCHGEPPVRLTLRADDGELEIEVTDHGPGLSPEALAHVFDRFYKADSARPRSPGSGLGLAISLANARLHGGDLVAGNAGGGGARFVLRLPRHHEEAE
>NZ_CP045480.1|WP_153034215.1|7231934_7232417_-|hypothetical-protein
MRRTLLGGLALLLAGCGVSPSGITTGTDAPTGVAPEISLFFVDARQRLQPQPRPTGKLGTITEALALLLTGPGPDSPLHTEISASGQTRTVVDTTADQILVRLPLAERDLTALGVDQVVCTALGVHRQGGGSPSAVVRVRFTVPHEEPGPPRRCPVLPAG
>NZ_CP045480.1|WP_153037421.1|7230780_7231938_+|acyltransferase-family-protein
MPGLDGLRGVAVAGVLLFHAGHFGGGFLGVDLFFALSGFLITGLLLRDGTGSPRAFWGRRARRLLPALTVMLAGTTLAVWALGDKNLWSTALADGPWVQANLVNWHLLAESAAYWDRFGPGRVFGHLWSIAVEEQFYLLWPVVVLLIVRAGGRAGHRVALVAALASVLSLVLMVFLFTPSDSTRVYTGTDTRAFSLLLGALMATAPATRLVSKVASREVVLALLFGVLAVFWLVADGENAHWLFRGGLFAHSLLAAALIALCAQTPGSPVTRALGWAPLRGLGSVSYSLYLWHWPVFLVLSEERIGMTGWARTAIVCAVSLALAVLSKVLVEDPIRFRATWARGRTGVGAVAVATLALAALWVAVPRPPVVQVDVTGLVVPMVTS
>NZ_CP045480.1|WP_153034214.1|7229712_7230690_+|serine-hydrolase
MDAEPKIYGDERLATRLGELLGPRHPVAAAALVSDQDVAVAGLRADLDADFEIGSITKGVTGLLYADALARGEIGQDTTLGELLPLGDVPAARLTLRSLSTHSSGLPRLPKSAHPLRRTIALWRHGTNPYGEDLGQLLDQARGVQVGKPRPRYSNFGFELLGHALAAAASTTYADLVHERIAKPLDLDFSVPATNAQLRPGALTGRSRRGKPREPWTGEALGPAGGIRASINAMARFTAAVLDGSAPGTAALDPVAPFGAGGRIGAAWLTIRVKGRSVTWHNGGTGGFRTWLGFDREAGTGAVILSATSLPVDRQGFALLSGSGQ
>NZ_CP045480.1|WP_153034224.1|7239324_7239906_+|TetR-family-transcriptional-regulator
MPTSADDSFIRAARRRQLVECAVEMIAEHGLAEASTVRIAKHAGVSRGVLTYHFRDRAELLNQVVRRVYELGAEVIGPAVTEAASPREALLAFIGGSVELHARYPRHLAALTEIFAAEARHDEQRRHARELDDLAAILRAGQEQGQFRAFDIDVMATTIRRALDGALAAIAGGVPADRYATELREIFDAATRL
>NZ_CP045480.1|WP_153034225.1|7239914_7240268_-|VOC-family-protein
MDLYSIVGVSDRKRAVEWFGVFFGRPADEVIGEEYLWQVGENAWVVVDDRDVRSGLVGRAMITFGVTGLDDILARLVANGIEHEPVETYGNGVRHVDVVDPDGNRLSLAEAPADHPG
>NZ_CP045480.1|WP_153034226.1|7240322_7242236_-|prolyl-oligopeptidase-family-serine-peptidase
MALPPLIDVGTLFADPEFSAAVISPDGTRIAYLAPKYGRTNVWVRGVEEEHADAVCVTHNARRGIKSFWWTDDPRWLLYRQDTDGNEDWHLFRVDLDAPEAPPVDLTPMPPGSRVVGADVLKAFPGKVMVAMNRRPMFFDTFLIDIATGETTVHLEQPDLMGGYLVGPRGEARFYTELADDGVVEYHAIDPRTREKRLVRRQGGPEHPMGIYPQLVTPDGDGLILGAFQDSDDLSLIRVDGETGEETVVAAVDGHSFCTMGQLSLDFGIPASVFTSRRTGALLAARFVGDRPRIEVLDPDFAEVYAALSQLSGGVLSALSSDDAEQRWVATFDHDREPGLTYFYDHGTGESRLLFRPFPQLDPAELAPMTGVHITARDGLPLPAFLTLPVGVDPVGLPLILLVHGGPWVHDGWGYNREVQFFANRGYAVLQVNYRGSSGYGKRHLTSAIGELAGKMHDDLLDAVDWAVERGYADPDRIGIFGGSYGGYATLVGVTFTPDRFAAAAEYVGISSLVNFMETTPEFVKPWLRNNWLRYGGDPADPEQRADLLARSPITRVHEVRTPLLIAQGAQDARVVQAESDNMVEALRAGGVEVEYLVFEDEGHDFQNPENLVTVFHAVDRHFGKHLGGRSGSPAGR
>NZ_CP045480.1|WP_153034227.1|7242298_7243123_-|NAD(P)-dependent-oxidoreductase
MGVSMTVSVLGMGAMGQALAAAFVRAGRPTVVWNRSAGKTEAVTGLGAVRAASVAEAVLAADLIVVCVLDHAAVREVLEPVAAHLGGRVLLNVTNGTADQAREVAAWAAGHGVSYLDGGIMAIPQTIGLPASTILFSGSREAYDRWADALGAWGTGNFLGEEPGLAALHDLALLGAMYGMFAGAFHATAMVGTEGVPTGRFTTELLVPWLRSMVDVLPMLVDAEVSAEQRLVEQAALANIVGTAAAQGVPGRMTAPIRALLTDHDRDPDHADFA
>NZ_CP045480.1|WP_153037422.1|7243198_7243468_-|transcriptional-regulator
MVSGKWKVLLLWELHERPCRFGELRRRLTGISEKVLSAQLRELEADGLCRRVEYPGAVLHVEYSLTDSGTALLEALVPITEWSLAHLGN
>NZ_CP045480.1|WP_153034228.1|7243602_7244403_+|LLM-class-flavin-dependent-oxidoreductase
MTNQALWLPLFDDLADPRTVARLAAEAEAGGWDGVFVWDHVRWQAPVRQVADPWITLTAMATATERLRFGPMITPLARRRPVKVARETATLDQLSGGRLTLGVGLGSDRFGQELSKTGEQLDDRVRARMLDESLEILTAAWSGEPVHHHGEHYTVDGIEFLPRPAQRPGIPVWAAGFPGNVKPLRRAARHDGFFPVNLEHPDQLAEVVSTITGLRNTTAPYDYAVALAPGTDPAPYAEAGATWVLAEFSPGVSLDEVRGVLREGPR
>NZ_CP045480.1|WP_153034229.1|7244408_7244861_-|VOC-family-protein
MSDFYHLCFVVQDIERATADLTRAVGVRWSPIRDGKLGDWDYRIVFSVEGPPFFEVIQGDPGSPWDATAGSRFDHIGYWSEDVNADKHRLSERGARLEFDSCPYGRSFTYHRIDSIGARVELVDIAAQEGFLRTWSPGGAPMPPLEPLEP
>NZ_CP045480.1|WP_153034230.1|7244866_7245514_-|deaminase
MNQLLRVQNFNVSADGFGAGENQSLERPFGDADPGDMFAWAGATASWPNRTDPGGSRGLDDYLTRDFAHNIGAEIMGRNKFGPQRGPWTDHDWLGWWGDEPPFHTPVFVLTHHPRPSFTLSDTTFHFVDGEPAAVLEQAKEAARGKDVRLGGGATTIREFLDADLVDTLHVAVSQVKLGSGTRLWESPDELRDRFHVDVVPSPGGAVTHHLFWRK
>NZ_CP045480.1|WP_153034231.1|7245666_7246269_+|hypothetical-protein
MTCEAEQPGRLRPLRRTEVLSRSLHTIEHTGSAYTVEVDTTRDWQARLYRDGEGHAVADMPATFPVPGGKIEVDSSLYGVTRVHLVLDSGEERRLAPVAGTAEHLRAALARRYPRVSRAIGVAAILVLVVNLVTAVPTALEFLTRIPKVAAHFGTFTSPLALPGWLNLALLFAGVLAAVERVLTLRKNRVLDIETMWASL
>NZ_CP045480.1|WP_153037423.1|7246265_7247168_-|WYL-domain-containing-protein
MLEILQAGGTRTVADLAGRLEVDERTVRRYVDHLLDLGIPVRSIRGRHGGYRLAAGYRMPPLMLTGEEALAVLLGLHAGRSTSTAESAAAKVRRVLPDPLARRLDALLSTAGFTAPARSGLSAEAGVLFEVAEAARDRCPIRIDYTAGHGGTSERTVHPYGIVAHSGRWYLTGADSSSARVRTFRVDRITALEVLDGTFDAPAGFDPAEHVLTSLAEAPHRYEVSLRIQATAEHIRTLFPPAVATLEAITGDEIRVRIRAQHLDWIATRLAALDRPFVIERPDDLRDLVRELAQRLSSYL

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Crispr_ID: NZ_CP045480_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045480_8

9358034-9358117

Orphan

Consensus_repeat	Method
TGCGACTTCACCGAGGCCGACCTC	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of NZ_CP045480_8

>merge|NZ_CP045480|8|9358034-9358117|CRISPRCasFinder
TGCGACTTCACCGAGGCCGACCTCCGCGGCCTGGTGACGCAGGGCTGCACCTTCGACGAATGCGACTTCACCAAGGCCGACCTC

>NZ_CP045480|8|8|9358034-9358117|CRISPRCasFinder
TGCGACTTCACCGAGGCCGACCTC	CGCGGCCTGGTGACGCAGGGCTGCACCTTCGACGAA
TGCGACTTCACCAAGGCCGACCTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045480.1\|WP_153035889.1\|9362134_9362986_+\|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase	unknown	unknown	gnl\|CDD\|237637
NZ_CP045480.1\|WP_153035879.1\|9352299_9353124_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293798
NZ_CP045480.1\|WP_153035878.1\|9351689_9352274_-\|Fe-S-cluster-assembly-protein-HesB	unknown	unknown	gnl\|CDD\|132296
NZ_CP045480.1\|WP_153035893.1\|9369480_9369933_-\|HNH-endonuclease	unknown	unknown	gnl\|CDD\|224321
NZ_CP045480.1\|WP_153035876.1\|9349665_9350889_-\|NADP-dependent-isocitrate-dehydrogenase	unknown	unknown	gnl\|CDD\|236226
NZ_CP045480.1\|WP_153035894.1\|9369999_9373323_-\|DNA-polymerase-III-subunit-alpha	unknown	unknown	gnl\|CDD\|235553
NZ_CP045480.1\|WP_153037635.1\|9366712_9367309_-\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP045480.1\|WP_153035892.1\|9368580_9369435_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|225375
NZ_CP045480.1\|WP_153035888.1\|9361118_9362129_+\|EamA-like-transporter-family-protein	unknown	unknown	gnl\|CDD\|377396
NZ_CP045480.1\|WP_153035891.1\|9367357_9368584_+\|amidohydrolase-family-protein	unknown	unknown	gnl\|CDD\|238624
NZ_CP045480.1\|WP_153035883.1\|9354978_9356160_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|225371
NZ_CP045480.1\|WP_153035880.1\|9353120_9353693_-\|Fe-S-cluster-assembly-protein-HesB	unknown	unknown	gnl\|CDD\|132296
NZ_CP045480.1\|WP_153037634.1\|9363063_9363297_+\|DUF3017-domain-containing-protein	unknown	unknown	gnl\|CDD\|378602
NZ_CP045480.1\|WP_153035877.1\|9351083_9351449_+\|DUF2203-family-protein	unknown	unknown	gnl\|CDD\|378330
NZ_CP045480.1\|WP_153035881.1\|9353748_9354393_-\|spermidine-synthase	unknown	unknown	gnl\|CDD\|223498
NZ_CP045480.1\|WP_153035882.1\|9354410_9354929_-\|TrmH-family-RNA-methyltransferase	unknown	unknown	gnl\|CDD\|349964
NZ_CP045480.1\|WP_153035885.1\|9356754_9357927_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|182234
NZ_CP045480.1\|WP_153035884.1\|9356248_9356566_+\|metalloregulator-ArsR/SmtB-family-transcription-factor	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|223713
NZ_CP045480.1\|WP_153035887.1\|9358622_9361004_-\|DUF4237-domain-containing-protein	unknown	unknown	gnl\|CDD\|379424
NZ_CP045480.1\|WP_153035890.1\|9363366_9364851_+\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|312032

Protein	Function_ID	Function_description	E-value
NZ_CP045480.1\|WP_153035889.1\|9362134_9362986_+\|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase	gnl\|CDD\|237637	PRK14193, PRK14193, bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional.	1.60022e-179
NZ_CP045480.1\|WP_153035879.1\|9352299_9353124_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293798	cd07712, MBLAC2-like_MBL-fold, uncharacterized human metallo-beta-lactamase domain-containing protein 2 and related proteins; MBL-fold metallo hydrolase domain. Includes the MBL-fold metallo hydrolase domain of uncharacterized human MBLAC2 and related proteins. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	6.24235e-22
NZ_CP045480.1\|WP_153035878.1\|9351689_9352274_-\|Fe-S-cluster-assembly-protein-HesB	gnl\|CDD\|132296	TIGR03252, TIGR03252, uncharacterized HhH-GPD family protein. This model describes a small, well-conserved bacterial protein family. Its sequence largely consists of a domain, HhH-GPD, found in a variety of related base excision DNA repair enzymes (see pfam00730). [DNA metabolism, DNA replication, recombination, and repair].	3.95684e-98
NZ_CP045480.1\|WP_153035893.1\|9369480_9369933_-\|HNH-endonuclease	gnl\|CDD\|224321	COG1403, McrA, Restriction endonuclease [Defense mechanisms].	5.4419e-14
NZ_CP045480.1\|WP_153035876.1\|9349665_9350889_-\|NADP-dependent-isocitrate-dehydrogenase	gnl\|CDD\|236226	PRK08299, PRK08299, NADP-dependent isocitrate dehydrogenase.	0
NZ_CP045480.1\|WP_153035894.1\|9369999_9373323_-\|DNA-polymerase-III-subunit-alpha	gnl\|CDD\|235553	PRK05672, dnaE2, error-prone DNA polymerase; Validated.	0
NZ_CP045480.1\|WP_153037635.1\|9366712_9367309_-\|TetR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.4192e-05
NZ_CP045480.1\|WP_153035892.1\|9368580_9369435_+\|alpha/beta-hydrolase	gnl\|CDD\|225375	COG2819, COG2819, Predicted hydrolase of the alpha/beta superfamily [General function prediction only].	1.52989e-21
NZ_CP045480.1\|WP_153035888.1\|9361118_9362129_+\|EamA-like-transporter-family-protein	gnl\|CDD\|377396	pfam04657, DMT_YdcZ, Putative inner membrane exporter, YdcZ. DMT_YdcZ is a family of putative inner membrane exporters from both Gram-positive and Gram-negative bacteria.	5.11494e-19
NZ_CP045480.1\|WP_153035891.1\|9367357_9368584_+\|amidohydrolase-family-protein	gnl\|CDD\|238624	cd01299, Met_dep_hydrolase_A, Metallo-dependent hydrolases, subgroup A is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a conserved metal binding site, involving four histidines and one aspartic acid residue. In the common reaction mechanism, the metal ion (or ions) deprotonate a water molecule for a nucleophilic attack on the substrate. The function of this subgroup is unknown.	3.31817e-92
NZ_CP045480.1\|WP_153035883.1\|9354978_9356160_-\|MFS-transporter	gnl\|CDD\|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	1.52289e-74
NZ_CP045480.1\|WP_153035880.1\|9353120_9353693_-\|Fe-S-cluster-assembly-protein-HesB	gnl\|CDD\|132296	TIGR03252, TIGR03252, uncharacterized HhH-GPD family protein. This model describes a small, well-conserved bacterial protein family. Its sequence largely consists of a domain, HhH-GPD, found in a variety of related base excision DNA repair enzymes (see pfam00730). [DNA metabolism, DNA replication, recombination, and repair].	1.80085e-91
NZ_CP045480.1\|WP_153037634.1\|9363063_9363297_+\|DUF3017-domain-containing-protein	gnl\|CDD\|378602	pfam11222, DUF3017, Protein of unknown function (DUF3017). This bacterial family of proteins with unknown function appear to be restricted to Actinobacteria.	1.38762e-10
NZ_CP045480.1\|WP_153035877.1\|9351083_9351449_+\|DUF2203-family-protein	gnl\|CDD\|378330	pfam09969, DUF2203, Uncharacterized conserved protein (DUF2203). This domain, found in various hypothetical bacterial proteins, has no known function.	2.26624e-42
NZ_CP045480.1\|WP_153035881.1\|9353748_9354393_-\|spermidine-synthase	gnl\|CDD\|223498	COG0421, SpeE, Spermidine synthase [Amino acid transport and metabolism].	1.72119e-23
NZ_CP045480.1\|WP_153035882.1\|9354410_9354929_-\|TrmH-family-RNA-methyltransferase	gnl\|CDD\|349964	cd18091, SpoU-like_TRM3-like, SAM-dependent tRNA methylase related to TRM3. Yeast tRNA (guanosine(18)-2'-O)-methyltransferase TRM3 catalyzes the formation of 2'-O-methylguanosine at position 18 (Gm18) in various tRNAs. TRM3 is similar to C-terminal domain of TAR (HIV-1) RNA binding protein 1 (TARBP1), a protein binding to TAR, which functions as a RNA regulatory signal by forming a stable stem-loop structure to which transactivator protein Tat binds. The role of TARBP1 is believed to be to disengage RNA polymerase II from TAR during transcriptional elongation. TRM3 and the C-terminal methyltransferase domain of TARBP1 are members of the SPOUT methyltransferase superfamily.	1.17287e-41
NZ_CP045480.1\|WP_153035885.1\|9356754_9357927_+\|MFS-transporter	gnl\|CDD\|182234	PRK10091, PRK10091, MFS transport protein AraJ; Provisional.	1.24786e-93
NZ_CP045480.1\|WP_153035884.1\|9356248_9356566_+\|metalloregulator-ArsR/SmtB-family-transcription-factor	gnl\|CDD\|223713	COG0640, ArsR, Predicted transcriptional regulators [Transcription].	9.41607e-11
NZ_CP045480.1\|WP_153035887.1\|9358622_9361004_-\|DUF4237-domain-containing-protein	gnl\|CDD\|379424	pfam14021, TNT, Tuberculosis necrotizing toxin. This is the C-terminal domain secreted by Mycobacterium tuberculosis (Mtb). It induces necrosis of infected cells to evade immune responses. Mtb utilizes the protein CpnT to kill human macrophages by secreting its C-terminal domain (CTD), named tuberculosis necrotizing toxin (TNT) that induces necrosis. It acts as a NAD+ glycohydrolase which hydrolyzes the essential cellular coenzyme NAD+ in the cytosol of infected macrophages resulting in necrotic cell death. CpnT transports its toxic CTD from the cell surface of M. tuberculosis by proteolytic cleavage, where the toxin is cleaved to induce host cell death. Structural analysis determined that the TNT core contains only six beta-strands as opposed to seven found in all known NAD+-utilizing toxins, and is significantly smaller, with only two short alpha-helices and two 3/10 helices. Furthermore, the putative NAD+ binding pocket identified Q822, Y765 and R757 as residues possibly involved in NAD+-binding and hydrolysis based on similar positions of catalytic amino acids of ADP-ribosylating toxins. While glutamine 822 residue was detected to be highly conserved among TNT homologs.	8.27605e-33
NZ_CP045480.1\|WP_153035890.1\|9363366_9364851_+\|alpha/beta-fold-hydrolase	gnl\|CDD\|312032	pfam08386, Abhydrolase_4, TAP-like protein. This is a family of putative bacterial peptidases and hydrolases that bear similarity to a tripeptidyl aminopeptidase isolated from Streptomyces lividans. A member of this family is thought to be involved in the C-terminal processing of propionicin F, a bacteriocidin characterized from Propionibacterium freudenreichii.	8.73413e-20

>NZ_CP045480.1|WP_153035885.1|9356754_9357927_+|MFS-transporter
MPIALLALAIGAFGIGTTEFVMMGVLPETAADFGVSIPTAGHLISGYALGVVIGAPLLTAVAVRLPRKTMLLAMMAMFTVGNLLFALSPNHEWGVIFRFLAGLPHGAFFGAGAVVASSLVGRENRAKAVSMMFVGLTLANVIGVPLGTLLGQQVGWRATFGVVAVIGLVAMAAIQKLVPFQGKPAEGSLRGELGAFRRPQVWFALAIVTFGLGGVFACLSYIAPMLTDVAGYAPGDVTLLLSLAGLGMTLGNLLGGRLADRALMPSLYVALTALAAVLAVFTVTAQGKVGAAITVFGIGVAGFMIGPMLQARIMEKAGGTPSLVSAAVQSAFNIANSIGAYLGGLVIAGGLGLVAPNWVGASLAVLGLSIAVVSGLLDRREQPTPAPVPA
>NZ_CP045480.1|WP_153035884.1|9356248_9356566_+|metalloregulator-ArsR/SmtB-family-transcription-factor
MPTETAPAYTYPDRDEIRIEPVLHALADPVRLEIVRQLAATGEIACGNLDVRVSKSTLTHHLRTLREAGVIMGRQQGTARYNSLRQKDLDALFPGLLNGILHAPR
>NZ_CP045480.1|WP_153035883.1|9354978_9356160_-|MFS-transporter
MPDSSRRTYVLALGAFSVGTSAYVVAGLLPALVSALHVSTAAAAQLVTAFAIAYAVGAPLLSALTSQWERRTLLVAALAVTAAGNLLAALVTGYPLLFGARIVTAIGAAVYTPVASAVAAELTPPERRGRAVAMVFGGLTVATILGVPLGSLMSQHGGYRLVFALVGVVALAGAVAVRLMLPSVAPQPPVPILTRFTVAKDPRVLALLAATALGCLGAFTVYTFITPLLAETAGVHGTLVSLLLFAYGAGGVLGNSVGGRITDRWGSRRPLIAVMSAMTLTLAVMPFTATSVAGAAVTLFVWGLSTWSVNPPIQHRLIEVAGPSAGLALSLNASAIYLGVGLAGVAGGVVTRFGGPPLLPSVAAVLTVCAGSIAMLAWRRRAVVAPPVPAAVG
>NZ_CP045480.1|WP_153035882.1|9354410_9354929_-|TrmH-family-RNA-methyltransferase
MSPAIRVRTPGELRASRRRRAHRCWGHLLAAPLWPLHGANLGTLLRTCDAVGACLAVPRFPWVPEALRRGNTLRQPACVHWVNDPLGWLAREREAGSAVVGVELADESIRLADLPAARGRTIVVLGHEQHGVPPDALDLLDSVVEIPMVGTGSSLNVAVAGSLVLYKLAGLV
>NZ_CP045480.1|WP_153035881.1|9353748_9354393_-|spermidine-synthase
MTEVLAEVEGVCGQLVLRQAGADFEVIANGVFLMDTRNGESERLLVSVAADLVPGRARLLIGGLGVGYSLRAALDHAGVGEIFVVEREPAVIEWNRTGPLRAVHGDALADPRVTVVEADLVRWLRKTEETFDALCLDIDNGPKWTVTAGNASLYSAAGLDDLAARLRPGGVLAVWSAEASDEFTARLRDRFNEVRVLEIPVPRGEPDVVWIARV
>NZ_CP045480.1|WP_153035880.1|9353120_9353693_-|Fe-S-cluster-assembly-protein-HesB
MTRKLRLTGDAAADKLLSDDPFALLTGMLLDQQIAMEIAFIGPRKIADRMDGFSVTKIAEADLEEFVELCVRKPAIHRYGGSMARRVHALAQHVVENYGGKTDGIWKKGKPDGKEVLKRLKALPGFGDQKARIFLALLGKQRGVQPEGWREAAGAYGEEGSHRSIADVTSPESLAEVRAFKKATKAAAKQ
>NZ_CP045480.1|WP_153035879.1|9352299_9353124_-|MBL-fold-metallo-hydrolase
MSPGNLDVRWHPGHPVPKFDTAPPLQVHAYDERTLILRQNKALNYEAPFLFLLSGDERSLLLDTGATADPAYFPLRATVDDLIGDRELVVAHTHGHGDHVAADGQFADRPRTTVVGRELADVAEFFGFRDWPEDVRQFDLGGRVLDLIPGPGHQDAAVVFHDRETGILFTGDTLYPGRLYVFDLPAYTATIDRLIGFCGQKQVTHVLGCHIEMTAEPGVDYPIGTTYQPDEPPLQLTPGHLRDLRAALAKVDGGHGIHVFDEFIVHHHAVHRHR
>NZ_CP045480.1|WP_153035878.1|9351689_9352274_-|Fe-S-cluster-assembly-protein-HesB
MTRTLHLTGDAAADELLSADPLALLTGMLLDQQVAMEVAFIGPKKIADRLGADRLDAAKIAEHDPEEFAALCATPPAVHRFPGSMAKRIQALCQFIVEHYDGDTAAIWSEGAPTGKEVLKRLKALPGYGDQKARIFLALLGKQRDVQPEGWREAAGAYGEEGSRRSIADVTSPETLAEVRAFKKATKAAGKKTG
>NZ_CP045480.1|WP_153035877.1|9351083_9351449_+|DUF2203-family-protein
MGLFTVPEARAELEQLKPCIEELITLRADAAELAASLTPEGTATPLGGLPELKAAQARLDELMSTIQQTGAELKGFAPLLIDFPADLDGVPVLLCWLEGDEGLTWYHRADLGFAGRRRLDA
>NZ_CP045480.1|WP_153035876.1|9349665_9350889_-|NADP-dependent-isocitrate-dehydrogenase
MAKIKVEGTVVELDGDEMTRIIWQFIKDKLVHPYLDVNLEYYDLGIEERDRTDDQITVDSANAIKRHGVGVKCATITPDEARVEEFGLKKMWRSPNGTIRNILGGVVFREPIIIQNIPRLVPGWTKPIIIGRHAHGDQYKATDFKVPGPGTLTMTYTPQDGSEPMEFEVAQYPEGGGVAIGMYNFRRSIEDFARASLQYGLDREMPVYMSTKNTILKAYDGMFKDVFQEIFDAEFKADFDAKGLTYEHRLIDDMVAAALKWEGGYVWACKNYDGDVQSDTVAQGFGSLGLMTSVLRTPDGKTVEAEAAHGTVTRHYRQHQQGKPTSTNPIASIYAWTRGLEHRGKLDSNAELIGFANKLEQVVIETVESGKMTKDLALLVGKDQPFQTTEEFLATLDENLAKKVAQG
>NZ_CP045480.1|WP_153035887.1|9358622_9361004_-|DUF4237-domain-containing-protein
MCRALPERTSQNVGVAQPTTQLNATEQDTLVKQIGLALLRAAPRDWQRVTAEYRAVGRYHELTGEIVTADGDSREWVATHDIATLFGRLRGGMYRDGRGTWFNARYQLDHPSSYNLEYDRDEPTWDLMPPPQAYADELRMFPRAEENIPEWLMRRMSGLGPERPGPRFRIARVFDGTDPAGHPVITRPDLDHDEQDRLLDYLDAAPVVVPGRGYDTDRLAEVPEAAVPIAFHSDGTWIWPAAVNYYLRTYGVSPEQDLIDHIHQHNFTVAEVPEATRQAAAGYVHNSGPPQRPGAPSSPPPVAPPAPVAPPAPAAPPEPQFEQFDEPQQSYNEAAYDDQYEAEYDDKTPQGQDQYATEPHAYPDPQDGYQPGFDDQGFTEPEPAAHGAHEVDIDDEDEFVPAGPDQATRFTPAPKPDVPAAAPTQVAMSPVAPGGPPPVEEPEPVEHGDPVLNDLQDKLDELRIPDEEYRIGEPAEHGWSLERIDAGWRVGWYDGELTNPAVFGDADDAAAFMLGKLLLNGRPQPRSQAQPPAAPPAPPPPQPQAPPPPPPQAPPAAPPTQVVAPVREEPPEPPQQPFRQPPPRQASTPVGALLDGDQAGPGLMTTLTPEVAPPAPPAPPSRPEPPARPPEPAPTQQVQVPPVEPPRPATPPAPPRPAPRREDPAAGGSGGGAGGQQWPIKPLAGEPPLTLFRGKELRELPAGSELDRFGGPNGNLTYVAGTPFEERSLVPEWVNRPYHVYRVQRPLEALAGIAIPWFNQPGGGAAYLLPASIEELLNEGDLIELDPGEPPVD
>NZ_CP045480.1|WP_153035888.1|9361118_9362129_+|EamA-like-transporter-family-protein
MSTVREPTGTVTAPERAPSVAAKVLGVSLAVFSGVTMAVQGRINGQLGVELGDPMLAAVFSFGGGLVLLLAALPFAPKMRKGVGRLRDAVRAGELRPWHCLGGLAGAMFVAGQALVVVAIGVAMFTVGVVAGQTVSSLAVDRAGLGPAGPRPLTWPRVVGAVLTLVAVLGSVSGGLGETDAGELWLMVLPLVAGFCVAVQQAVNGRVGAASGSALTATLGNFTVGFAALLLAWVISLLIRGGPSGFPSNPLLYAGGIVGILFISIASLVVRWTGVLLLGLAAIAGQLIGALLLDLLLPAHGEHLAPETIGGVVLALIAIGIAALGGGRRRARGLPQ
>NZ_CP045480.1|WP_153035889.1|9362134_9362986_+|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase
MTATVLDGKATKDAIFDELKPRVAALAERGITPGLATVLVGDDPGSHWYVKAKHADSAKVGVNSIRRDLPAGITQDKLEAVVDELNADPACTGYIVQMPLPKHLDTGAILERIDPDKDADGLAPVSLGRLVLGETAPLPCTPLGIVELLRRYDVPLDGARVTVIGRGITVGRPLGLLLTRRSENSTVTLCHTGTRDLAAEVKRADIVVAAAGVPGIITPEMVKPGAAVLDVGVSRVDGKIAGDLAAGVEEVAGFISPNPGGVGPMTRAMLISNVVEAAERAAR
>NZ_CP045480.1|WP_153037634.1|9363063_9363297_+|DUF3017-domain-containing-protein
MALVALAALRIGMYHWRQGAALIGGALLTAAVLRGVLSDARAGLLAIRGKAVDVITYTTFAALILFVALTITRGPGV
>NZ_CP045480.1|WP_153035890.1|9363366_9364851_+|alpha/beta-fold-hydrolase
MIRSTFFATALTGVLALAVVVAPAATAGPSLAWGPCTESGLERYQCAIAEVPIDHAHPDGPKLGLSVVRQPAADPARRIGTLFLAVGGPGGSGVDSAKGRELAQGELAERFDVVTFDQRGIGRSGQIRCFGSAAEQEEFWAGAVIPPANRAEERAAAERSRAYAAGCAEHGGELRKHLTTADAARDLDWLREAVGDAKLTYSGGSYASYLGQVYGAMFPERVRALQLTAMIDPEGYTNRTTSTLLERSAGTEGVLREFARLCDSAGPRCALSGNALARNAAVLDRLKQGPIHVGSLAVHYRDVVPTQANMLYDTQVGWPAFAALVAELERGPSGDEALVSEILNASAFRLDFLDSFTAITCADVRAPQLPEAWPLLNRAFDAQSPHYGRSWWYLTQPCGAWPPSPQRHTGPWQLRSETPALLINNRYDPVTPLSYAHTAQRLLGNAHLLVVEGHGHTPQSTCADEARTHYLLTQSPPTGHTSTCPATPVPFPPT
>NZ_CP045480.1|WP_153037635.1|9366712_9367309_-|TetR-family-transcriptional-regulator
MILSSTERTGDARERLLARLLDAFDEALPAPEVSLREIAARAGTSHALLRYHFGSLPGVLAAMLKAQRARDNEALFEAAQQGTFDDLVVAIWRTYTRPEQLSRVRGFFHVVGLAAYSPENFREFIDSLDDLTKILASLAEREGLDAEEALTTATVTIAAIRGLLLQEVLTPAAHSEDAVALILRMRRDQSAPRTPPGP
>NZ_CP045480.1|WP_153035891.1|9367357_9368584_+|amidohydrolase-family-protein
MGPFQITGATVVDGSGRDPVDVAVTVEDGRIAQLGASSASGERLDAGGLTMTPGLIDAHVHLGLSSPIQPQFSFRLSAAEIAADIFATAGATLDAGFTTVRDTGGIDGGVVTTIAKGKVRGPRVLSCGPVQCQTGGHGYYGAEWEPTELWSSHHVPGLCALSMMSGNADELRGNVREAFRRGASFLKLCVTGGVVGAHDRLTDTQFTVDEIAVAVQEAAARGTYVTVHAHNNDGIRNAVEAGVRCVEHGTDLDESTATLMATNEVSLVPTFAVVEQLLHDTAGAGLDESARERVLGVRERMTEALAIATKAGVRIGLGSDLLGPAQHRRGEELTLRAQLQTPMDALVAATKTNAEILGLADRVGVIAAGMQADLVLWNGNPLDDPKLFTDPANAVLVVQAGRIVKDIR
>NZ_CP045480.1|WP_153035892.1|9368580_9369435_+|alpha/beta-hydrolase
MNTMWQGCLADTDYFEIRSSGGHDYGIWVTTPPGYDPATTPAPAVYVLDGNWAVGMTAPLIVTQLDPMQRIQPYIQISVGYAGDDAQHWDRLRNRDLVPPGEPIAKELIDAVEAGVQAGARTREESDAYLAELRDTHADAFLRFLTTELHPRIERDYGTATSGHGLFGYSYGGLFSLYTWLTSSTLFDSIGAGSPGVTGENSQIFTLLHELGDRLPAAQLHVTLNEQELLGDLPIYQNLTKNTATLLHHLTARNATVTSTVLSETHVTGLQASFLSYLRTCRAQ
>NZ_CP045480.1|WP_153035893.1|9369480_9369933_-|HNH-endonuclease
MDVLVLNAGYEPLQRVSVPHAVRMLVRNVAVVHEAGAGPAFGVYPRPRIVRLLKYVVMKWRYGAQPRWSRRGVLRRDKHLCAYCGRRAATVDHVVPLSRGGERTSWLNTVAACGGCNARKANNLPREVGMNLRFPPRVPTWDELSELVPR
>NZ_CP045480.1|WP_153035894.1|9369999_9373323_-|DNA-polymerase-III-subunit-alpha
MGWNNPPVRWQELERELSGQQPIPPESERDGGDSPAWTRRRDGYHPPADLRSRRGDDQAGAAVRVPYAELHCHSNFSFLDGASHPEELVEEAVRLGLDALALTDRDGMYGVVRFAEAAADLGLRTVFGTELSLGLSGPQNGVPDPEGESLLLLAYQQEGYGNLCRAITRGQLQGPQSEKGRPVYDLESVAEDTAGKCVVLTGGRRGAVRRALADGGLDAARARLDQLVALFGREHVVAELVSHGEPMDDHHNDAIRDLAESFGLPLIATGGVHYATPRRGRRLAAGLAAIRARRSIEEMEGWLPAADNAFLRSGAEMAEIFVRYPGAVQRAALLGTECAFDLSLVAPELPPFEVPDGHTEASFLRQEVMKGAAHWYAGNEDAYRQLEHELRIIEELGFPGYFLIVWEIVDFCRRNNIYCQGRGSAANSAVCFALGITKVDSVKWKLLFERFLAPDRDGYPDIDLDIESGRREEVIQHVYQKYGRLHTAQVANVITYRSRSAVRDAARALGYSPGQQDAWSKQLDRWGPLKSTKDDHEHDIPAEVLEMAEDLEGFPRHLGIHSGGMVICDRPVSEVCPIEWARMADRSVLQWEKDDCATAGLVKFDLLGLGMLSALHHMVDLVAEFEGMTVELGALDLEDKKVYEMLQRADAIGVFQVESRAQLATLPRLAPRKFYDLAVEVALIRPGPIQGGSVHPFIRRYTGKEEWDFDHPLLANALGKTYGVPLFQEQMMQIALDVAGFSAAEADQLRHAMGSKRSEKRMEQLRQRFYDGAEAKGVERELAARIFGKLQAFANFGFPESHALSFAYLVFASAYFKLYYPAAFCAALLRAQPMGFYSPQSLVADARRHGVVVLGPDVNASDWHATLEPHDDGKNAVRTGLATIRNIGEDVAKALVAERASGGPFADMADVARRVRLKTPQVEALATAGAFGCFEADRRKALWAAGAVAGERPEKLPGSAVGVAAPALPGMDDMELAVADVWATGMSPDSFPTQFVRDQLDALGALSAEALHGVEQGTRVLAGGAVTHRQRPATAGGITFINLEDETGMINVVCSAGLWRRYHRVARDSSALLVRGVIERADGVVNLIADRLQRLQLRIPAKSRDFR

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Crispr_ID: NZ_CP045480_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045480_9

9943582-9943657

Orphan

Consensus_repeat	Method
TACGGCCAGCAGCCCGGTTACGACC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045480_9

>merge|NZ_CP045480|9|9943582-9943657|CRISPRCasFinder
TACGGCCAGCAGCCCGGTTACGACCCCTACGGCCAGCAGCAACAGCAGCCGTACGGTCAGCAGCAGCCCTACGGCC

>NZ_CP045480|9|9|9943582-9943657|CRISPRCasFinder
TACGGCCAGCAGCCCGGTTACGACC	CCTACGGCCAGCAGCAACAGCAGCCG
TACGGTCAGCAGCAGCCCTACGGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045480.1\|WP_153037697.1\|9936871_9937228_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045480.1\|WP_153036374.1\|9954259_9955846_+\|choline-dehydrogenase	unknown	unknown	gnl\|CDD\|235000
NZ_CP045480.1\|WP_153036365.1\|9939628_9940009_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380033
NZ_CP045480.1\|WP_153036371.1\|9945482_9946529_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379274
NZ_CP045480.1\|WP_153037698.1\|9937742_9938564_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379262
NZ_CP045480.1\|WP_153036373.1\|9953204_9953444_-\|phosphoribosylformylglycinamidine-synthase-subunit-PurS	unknown	unknown	gnl\|CDD\|235659
NZ_CP045480.1\|WP_153036364.1\|9938776_9939613_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|252734
NZ_CP045480.1\|WP_153036368.1\|9941731_9942649_+\|lysozyme	unknown	unknown	gnl\|CDD\|119374
NZ_CP045480.1\|WP_153036367.1\|9940788_9941595_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|119374
NZ_CP045480.1\|WP_153037703.1\|9957356_9958439_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340863
NZ_CP045480.1\|WP_153037699.1\|9946533_9948804_-\|phosphoribosylformylglycinamidine-synthase-subunit-PurL	unknown	unknown	gnl\|CDD\|234921
NZ_CP045480.1\|WP_153036369.1\|9942772_9943333_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045480.1\|WP_153036366.1\|9940072_9940693_+\|type-VII-secretion-system-associated-protein	unknown	unknown	unknown
NZ_CP045480.1\|WP_153036372.1\|9952521_9953208_-\|phosphoribosylformylglycinamidine-synthase-subunit-PurQ	unknown	unknown	gnl\|CDD\|235140
NZ_CP045480.1\|WP_153037700.1\|9949009_9950605_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP045480.1\|WP_153037696.1\|9937277_9937493_-\|DUF397-domain-containing-protein	unknown	unknown	gnl\|CDD\|377231
NZ_CP045480.1\|WP_153036363.1\|9935155_9936694_-\|amidophosphoribosyltransferase	unknown	unknown	gnl\|CDD\|236113
NZ_CP045480.1\|WP_153037702.1\|9953583_9954021_-\|L,D-transpeptidase-family-protein	unknown	unknown	gnl\|CDD\|341130
NZ_CP045480.1\|WP_153036375.1\|9955826_9957320_-\|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|143417
NZ_CP045480.1\|WP_153037701.1\|9950655_9952323_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224055

Protein	Function_ID	Function_description	E-value
NZ_CP045480.1\|WP_153036374.1\|9954259_9955846_+\|choline-dehydrogenase	gnl\|CDD\|235000	PRK02106, PRK02106, choline dehydrogenase; Validated.	0
NZ_CP045480.1\|WP_153036365.1\|9939628_9940009_-\|hypothetical-protein	gnl\|CDD\|380033	pfam17844, SCP_3, Bacterial SCP ortholog. This domain is found in MSMEG_5817 gene product from M. smegmatis. It has been shown to be vital for mycobacterial survival within host macrophages. Crystal structure revealed a Rossmann-like fold alpha/beta two-layer sandwich forming a highly hydrophobic interface cavity and with high structural homology to the SCP family. Hence, it has been suggested that this domain may be involved in the interaction of apolar ligands through its hydrophobic cavity. Alanine-scanning mutagenesis of the hydrophobic cavity of MSMEG_5817 protein demonstrated that the conserved Val82 residue plays an important role in ligand binding.	1.1966e-54
NZ_CP045480.1\|WP_153036371.1\|9945482_9946529_+\|hypothetical-protein	gnl\|CDD\|379274	pfam13576, Pentapeptide_3, Pentapeptide repeats (9 copies).	9.32098e-07
NZ_CP045480.1\|WP_153037698.1\|9937742_9938564_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	4.53902e-09
NZ_CP045480.1\|WP_153036373.1\|9953204_9953444_-\|phosphoribosylformylglycinamidine-synthase-subunit-PurS	gnl\|CDD\|235659	PRK05974, PRK05974, phosphoribosylformylglycinamidine synthase subunit PurS; Reviewed.	9.97468e-34
NZ_CP045480.1\|WP_153036364.1\|9938776_9939613_+\|hypothetical-protein	gnl\|CDD\|252734	pfam04672, Methyltransf_19, S-adenosyl methyltransferase. This family contains a SAM (S-adenosyl methyltransferase) domain, with a central beta sheet with 3 alpha-helices on both sides. Crystal packing analysis of the structure Structure 3giw suggests that a monomer is the solution state oligomeric form. An unidentified ligand (UNL, cyan) was found at the putative active site surrounded by the residues His57, His170, Phe171, Tyr216 and Met22. The UNL is likely to be a phenylalanine or phenylalanine-like molecule. (details derived from TOPSAN).	2.13229e-86
NZ_CP045480.1\|WP_153036368.1\|9941731_9942649_+\|lysozyme	gnl\|CDD\|119374	cd06412, GH25_CH-type, CH-type (Chalaropsis-type) lysozymes represent one of four functionally-defined classes of peptidoglycan hydrolases (also referred to as endo-N-acetylmuramidases) that cleave bacterial cell wall peptidoglycans. CH-type lysozymes exhibit both lysozyme (acetylmuramidase) and diacetylmuramidase activity. The first member of this family to be described was a muramidase from the fungus Chalaropsis. However, a majority of the CH-type lysozymes are found in bacteriophages and Gram-positive bacteria such as Streptomyces and Clostridium. CH-type lysozymes have a single glycosyl hydrolase family 25 (GH25) domain with an unusual beta/alpha-barrel fold in which the last strand of the barrel is antiparallel to strands beta7 and beta1. Most CH-type lysozymes appear to lack the cell wall-binding domain found in other GH25 muramidases.	2.26067e-109
NZ_CP045480.1\|WP_153036367.1\|9940788_9941595_+\|hypothetical-protein	gnl\|CDD\|119374	cd06412, GH25_CH-type, CH-type (Chalaropsis-type) lysozymes represent one of four functionally-defined classes of peptidoglycan hydrolases (also referred to as endo-N-acetylmuramidases) that cleave bacterial cell wall peptidoglycans. CH-type lysozymes exhibit both lysozyme (acetylmuramidase) and diacetylmuramidase activity. The first member of this family to be described was a muramidase from the fungus Chalaropsis. However, a majority of the CH-type lysozymes are found in bacteriophages and Gram-positive bacteria such as Streptomyces and Clostridium. CH-type lysozymes have a single glycosyl hydrolase family 25 (GH25) domain with an unusual beta/alpha-barrel fold in which the last strand of the barrel is antiparallel to strands beta7 and beta1. Most CH-type lysozymes appear to lack the cell wall-binding domain found in other GH25 muramidases.	2.46646e-106
NZ_CP045480.1\|WP_153037703.1\|9957356_9958439_-\|MFS-transporter	gnl\|CDD\|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	9.87542e-10
NZ_CP045480.1\|WP_153037699.1\|9946533_9948804_-\|phosphoribosylformylglycinamidine-synthase-subunit-PurL	gnl\|CDD\|234921	PRK01213, PRK01213, phosphoribosylformylglycinamidine synthase subunit PurL.	0
NZ_CP045480.1\|WP_153036372.1\|9952521_9953208_-\|phosphoribosylformylglycinamidine-synthase-subunit-PurQ	gnl\|CDD\|235140	PRK03619, PRK03619, phosphoribosylformylglycinamidine synthase subunit PurQ.	1.93684e-143
NZ_CP045480.1\|WP_153037696.1\|9937277_9937493_-\|DUF397-domain-containing-protein	gnl\|CDD\|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	3.07142e-21
NZ_CP045480.1\|WP_153037700.1\|9949009_9950605_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	2.73011e-77
NZ_CP045480.1\|WP_153037702.1\|9953583_9954021_-\|L,D-transpeptidase-family-protein	gnl\|CDD\|341130	cd16913, YkuD_like, L,D-transpeptidases/carboxypeptidases similar to Bacillus YkuD. Members of the YkuD-like family of proteins are found in a range of bacteria. The best studied member Bacillus YkuD has been shown to act as an L,D-transpeptidase that gives rise to an alternative pathway for peptidoglycan cross-linking. Another member Helicobacter pylori Csd6 functions as an L,D-carboxypeptidase and regulates helical cell shape and motility. The conserved region contains a conserved histidine and cysteine, with the cysteine thought to be an active site residue.	3.69447e-21
NZ_CP045480.1\|WP_153036375.1\|9955826_9957320_-\|aldehyde-dehydrogenase-family-protein	gnl\|CDD\|143417	cd07099, ALDH_DDALDH, Methylomonas sp. 4,4'-diapolycopene-dialdehyde dehydrogenase-like. The 4,4'-diapolycopene-dialdehyde dehydrogenase (DDALDH) involved in C30 carotenoid synthesis in Methylomonas sp. strain 16a and other similar sequences are present in this CD. DDALDH converts 4,4'-diapolycopene-dialdehyde into 4,4'-diapolycopene-diacid.	0
NZ_CP045480.1\|WP_153037701.1\|9950655_9952323_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	5.87589e-114
NZ_CP045480.1\|WP_153036363.1\|9935155_9936694_-\|amidophosphoribosyltransferase	gnl\|CDD\|236113	PRK07847, PRK07847, amidophosphoribosyltransferase; Provisional.	0

>NZ_CP045480.1|WP_153036369.1|9942772_9943333_+|hypothetical-protein
MTYEEPGRKPPTGLLIGIAAGVVVLAVLGFTAFIAPGFLTGDPEPVAAPATTSSAPARTTTPPSSRPTETPSPAPSSAEPAPGGRGGSGPADASVEKVIKDFVAALNAGDANGAKELMCAGGRGDDSAVGALAAQKPSLAVSGLQAKSSKVLTGQVTGTAGGKPVEASVTATAAIGEACVGLFTVS
>NZ_CP045480.1|WP_153036368.1|9941731_9942649_+|lysozyme
MSMRRSRRLSGAVVTISAGLLLLGTLAPASASTYNDDTGTAPAEAVPAFIDGLPVDEYVRKYDHPIGSQIRLVEGDHSTEETKEAARREPAVGPDGKQVLASVEGIDVSGHQQNVNWQNWWNQGKRFAFVKATEGTGYKNPYFTQQYNGSYNIGMIRGAYHFALPDRSSGAAQADYFVNNGGGWSGDGKTLPGALDMEYNPYGATCYGKSQASMGAWVREFHDRYHARTGRWPVIYTSTSWWNQCVGTSQNFGSTVPLWVARYSSSVGTLPHGWGFYSFWQYTSTPIDFNRWNGDYAQLQKMATG
>NZ_CP045480.1|WP_153036367.1|9940788_9941595_+|hypothetical-protein
MRPFPCLAMCAGLALIAPAISAVPATADYSLAENNRAGSQIAAIEGVHGVPDHGRYAAEGQTLGHDVSGHQGAVDWPAAAGAGAKFVYVKATEGTGFTNPRFGQQYNGAHGAGLVRGAYHFARPDVSGGAEQAHYFVDNGGGWSGDGRTLPGALDVEYNPYSDDKCYGRDAAGMTAWIKDFSDTYAQRTGRAPAIYTSTSWWKKCTGDTAAFGGTNPLWLARYAPEIGPLPAGWAHQSIWQWADAGALPGDQNYFNGTEDRVTAMAGG
>NZ_CP045480.1|WP_153036366.1|9940072_9940693_+|type-VII-secretion-system-associated-protein
MAQRDDSDRATADGRPVAIPKITDEMRANARANPDSWLYVIDEAFDPNGPVPSWAVVGAYPVNTAGDVVEDFHPNDRYRPSPKALGFPEPGNELERLLQLVRTKHRPAGDLPRVILDSTLFVYAMSPVQRTVIGFHNTDGRVLVPAYTAKSLVPKDWPHARAVLGRDMVELLAGHPVAINPHDVVTAVVPAEHLLKALAEEAADQG
>NZ_CP045480.1|WP_153036365.1|9939628_9940009_-|hypothetical-protein
MPASRSVDPAELRTAVAAVVPWLTGDGPEPARQELAKAVRLSLRTLAADAPGRSVEVRVPPFAAVQCVDGPRHTRGTPPNVVETDPRTWLELATGRLDWAAAVDAGRVSASGSRADLAHWLPILRL
>NZ_CP045480.1|WP_153036364.1|9938776_9939613_+|hypothetical-protein
MPAGTAASSERVPVGVDPTRASIARVYDAFLNGKDNYEIDREVLRGVQQKAPEAQDLATENRGFLIRACRFLAGQTGVTQYLDLGSGLPTAENTHQVVQRLVPDSVVVYVDNDPVVLAHGRALLEENDQTHLTSANIFKPREVLENEDVKANLDFSQPIALLQAGTLHHHVGDPAEPAQIMREYIDALAPGSYVVISHFLDPENEHSPVARKMEEVFVHSPMGSGTFRTHKELLELFDGLEMVEPGLTRCADWWPDGPRIKPLNQVQHCIAGGIGRKN
>NZ_CP045480.1|WP_153037698.1|9937742_9938564_-|helix-turn-helix-domain-containing-protein
MVLGTQLRRLREREGVTRAEAGYSIRASESKISRMELGRVGFKERDVVDLLTMYGVDDPEERSAFVELVKQSNQPGWWNRYNDLMPRWFDDYVGLEEASQRIQTYELQFVPGLLQTEDYARAIVSHGRPESRDDDVERRVAIRMRRQKLLNRPEAPRLWAVVDESVLHRPIGGRKVFKEQLDHLLEMTTMSHISLQVVPYRLSGYSAEGAFTLLRFAEPELPNIVYIEHLAGALYLEKLADFELYSRALDRLAVDAETPERSRTTIAKIRAEL
>NZ_CP045480.1|WP_153037696.1|9937277_9937493_-|DUF397-domain-containing-protein
MPADLLAGAQWRKSSRSGALGNCVEVAPLATGEIAVRNSRFPTGPALVYTRAEMAAFLAGAKDGEFDDVLS
>NZ_CP045480.1|WP_153037697.1|9936871_9937228_-|hypothetical-protein
MRRLIDRGFQFVHPRSPEGEVLAVVGIRAHENVIDVVRLHAEDDVIATRMPGGEPDILAPRTTLWQVSGSVLTVIDQLLALPDQPAEVAVAAETGGQGGRGCWVPGRGGAAKWLPASA
>NZ_CP045480.1|WP_153036363.1|9935155_9936694_-|amidophosphoribosyltransferase
MVSDQSTTGPAVTDQPDPEPREECGVFGVWAPGEEVAKLAYYGLYALQHRGQEAAGISVSDGKQIVVFKDLGLVSQVFDEQVLSSLQGHIAVGHCRYSTTGSTIWENAQPIFRTTDTGSGLSFAHNGNLVNTAELRERTLAAGLKPHAGLTGSSSDSDLVCGLLASAAADRGIEAAALDLLPTLRGAFCLVFADESTLYAARDPHGVRPLVLGRLERGWVVASETAALDIVGASFVREVEPGELIAIDAEGLRSSRFANPEPKGCVFEYVYLARPDTSIAGRSVHATRVDIGKRLAKEFPADADLVIPVPESGTPAAIGYAQASGIPYGSGLVKNAYVGRTFIQPSQTIRQLGIRLKLNPLRDVIRGKRLVVVDDSIVRGNTQRALVRMLREAGALEVHVRIASPPVRWPCFYGIDFASRAELIANGVDADGVRRSIGADSLGYVSLEGLIAASEQPKSRLCSACFDGEYPIALPDDALIGKHLLESLDAADGAAKPVTPAGYGAEDAVRRP
>NZ_CP045480.1|WP_153036371.1|9945482_9946529_+|hypothetical-protein
MRRALKSPLALTIALAVVLLVGISAWLLTDPKTTRADALRTGGLAGGAIVALYALWLNDRRRKVEEGRQEIERQRHVLESHRAERDLERVSDERFAKAVELLGDDADQVRVGALHALAGLARTRVAYRQTVLDVLCSYLRRPFEQKDEQPENERERVVRQTAQRLIAELLPKRDDTEAEVYNLDLTTATLEQFDLSGRRVGELTLRHASLHRSTRFHEMRIEGPLWMTAAELHGKLRLHDSTIGRGWFSGTKFLAAAHFERSEFGEQVSFAGAVFSDEAVFEGTTFADSLSLHRTKFDDYLDFRITAVPVPLELYHTLVRPEREHELPAGLETQRQPNGDVRIVAVRP
>NZ_CP045480.1|WP_153037699.1|9946533_9948804_-|phosphoribosylformylglycinamidine-synthase-subunit-PurL
MTSTDTTEHAAATPDVPQPYLELGLAEDEYARIREILGRRPTDAELAMYSVMWSEHCSYKSSKVHLGYFGETTTDEMRSKMLAGIGENAGVVDIGDGWAVTFKVESHNHPSYVEPYQGAATGVGGIVRDILAMGARPLAVADPLRFGPADAPDTRRVLPGVVAGVAGYGNCLGLPNIGGEVVFDESYAGNPLVNALCVGAMRVEDLHLAHASGTGNKIILFGARTGLDGIGGVSVLASDSFSENTGRKKLPSVQVGDPFTEKVLIECCLELFAQKLVVGIQDLGGAGLSCATSELAAAGDGGMHIVLDRVPLRAEGMTPAEILSSESQERMCAVVAPSDVDAFMAVCAKWDVTATEIGEVTDGEHLVITWHDEVVVDVPPRTVAHQGPVYHRPFARPSTQDALQADTTASLERPSTGDEIRETVLKVISSPNQASKEWVTSQYDRYVRGNTVLAQPSNSGVIRIDESTGRGVAVSTDCNSKFVYLDPYLGTQLALAESYRNVATSGATPVAVTNCLNFGAPTDPGVMWQFERAVHGLADGCAELGVPVTGGNVSFFNQTGDTAILPTPVVGVLGVIDDVRRRIPTGIGAEAGESLLLLGDTHDELDGSAWAHIVHGHLGGLPPKVDLAREKLLAEILVAGSRDGMISAAHDLSDGGLAQTLVETVLIGQCGARVVLDDEQDPFVQLFSESAGRVLVAVPRTEELRFTEMCTARGLPWRKTGVVDPDSGSLEIQGVTSFGLDELRETWERTLPALFD
>NZ_CP045480.1|WP_153037700.1|9949009_9950605_+|ATP-binding-cassette-domain-containing-protein
MRLPERLTPLGYLLAVLRSRPWLAGGTAVLGALWLVPGALLPLVVGQAIDAGIAGADTAALVWNVVLIAGLGVLQTVFGAGLLFSAHGMWLHAASTTQRLVSHHTLRLGAGLRGQADTGDMMAIASSDENRVGAIFEVFGRVLGAVVAFLTVGIVLLGTSPLLAAVALVGVPLAVAGIGPLIAPLQRRQEAQREDLSTVNALAADIVSGLRVLRGVGGERQFAKRFATASQRVREQGNAVASSTSWLVGAEVLLPGLVTVAITWLGAKLAVAGTITVGELVAFYGASAFLIIPVSTTTEAAGSFSGAMVAARKVCKMLNLRPKLTDAADPIALPDGPLELHDTESGFTAVAGKLTVVESPDAEELAARLARFTDPAEPVLVSGVDVRRAALAELRSRVVYAHNQDVWFSGVLREQIVTPGSVTVEAALTAADADDIVDALPLGLDELIGERGREVSGGQRQRLNLARALALDADVLLLDEPTSAVDAHTEARITERVAELRRGRTTVVFSQSPLWRAVADEYVVKERQPCS
>NZ_CP045480.1|WP_153037701.1|9950655_9952323_+|ATP-binding-cassette-domain-containing-protein
MKAFRREFVLVILFFCLAGAAGLVGPQVLGLLVDSVVEGGGLSLDLLALVFVVVLVVQAVLKKAANRRAGLLGERVLAKTREEFVGDALKLPLGTVEAAGTGDLLSRATSDVDKVDYAMRYAVPEITVALITVALTVVAMVLTSPLLALGLLVAVPVLYLPTRWYWRRVPSVIERMLDAWGDVQSGLHESTEGARTADALGMIERRVADGDRRLARAVDGERHLRKLQVRWAPWLELSHALPVAAMLLIGAWAYTRGWVGLGTITTMVLYMQIMAGPLDELLWWIEDVQVSGTALRRVIGVRNAASTPPTGAESPSGTEIEVRDVRFGYSADREVLHGISLSIPRGQRLAIVGPSGAGKSTLGRLLAGIAAPDSGSVTIGGAEVSRLPEDVLRGEVLLLTQEHHVFAGTLRENLTLPAGTWSDEALFDALDSVGAGSWARSLPDGLDTKLSSSAVPAAMAQQLALARVVLADPHTLVLDEATSLLDTGSARELERSLTQVLAGRTVIAIAHRLHTAAAADRVAVIDGGTITELGTHEELLAADGPYARLVQAATA
>NZ_CP045480.1|WP_153036372.1|9952521_9953208_-|phosphoribosylformylglycinamidine-synthase-subunit-PurQ
MSARIGVITFPGTLDDVDASRAARYSDAEAVPLWHADHDLRGVDAVIVPGGFSYGDYLRCGAIAKFAPVMTEVVEAAAKGMPVLGICNGFQILCEAGLLPGALVRNHKLHFVCRDQWLRVENNTTAWSTRYEQGAEILVPLKSGEGGYVADQPTLDMLEGEGRVVFRYVGENPNGSRNDIAGITSANGRVVGLMPHPEHAIDALTGPSDDGLGMFYSAVDTLTGALTS
>NZ_CP045480.1|WP_153036373.1|9953204_9953444_-|phosphoribosylformylglycinamidine-synthase-subunit-PurS
MARVVVDVMPKPEILDPQGQAVAGALPRLGFEGVTDVRQGKHFVLEVDDSVDDETLAKIAEGLLANPVIEDWTVRRVDA
>NZ_CP045480.1|WP_153037702.1|9953583_9954021_-|L,D-transpeptidase-family-protein
MLRKITGVVAGSAAIGALGLFAAPSASAASMPCSAKASACVDLSAKQAWLAEGGEVTYGPVPMASGKSGYRTPPGTFKVTYKDIDHWSKAFDGPMPYSVFFTTSGIAFHEGNIKQQSHGCIRLTHNAAVTFYRALQPGEVVEVVR
>NZ_CP045480.1|WP_153036374.1|9954259_9955846_+|choline-dehydrogenase
MAERETFDYVIVGAGSAGCVLANRLSADPSVSVLLLEAGGEDTDDEFHIPAAFPSLFKTQHDWNYETVEQKYLGKTSYWPRGKVLGGCSSINAMIYIRGNRADYDRWRDEHGAAGWGYEDVLPYFIRAEGNTRLGGPLHGTDGPLHVEDRVFTHELSHAWVNSATTWGLKPTDDFNGENQEGAGLYQVTCRRGRRWSTADAYLRPALTRKNLVVRTHAQTTKVLLDGTKAIGVSYLDKGADRPVYAEREVLLSGGAVNSPQLLMLSGIGPAEHLRELGIDVAVALPGVGENLHDHPAAGIIWATKGTTDLVDAATPAGLVRYQLTKRGPLASNVGEAGGFMPTIDGLAAPDMQFHVAPTLFYDNGMREPTTPGFTSAATLVEVASRGRLRLRSANPLWRPEIDPSYYSEPADFTAMLAGLRTLMEIGRGGELKRYLDRPFLPESHDIDDDALTEHVRQNTQTLYHPVGTCAMGTGELAVVDPELKVRGVENLRVVDASIMPVVPRGNTNAPTVMVAEKAAELISASRA
>NZ_CP045480.1|WP_153036375.1|9955826_9957320_-|aldehyde-dehydrogenase-family-protein
MTAVQPKPATQETFDSLSPATDEVVGTYPVHTADDVEAAVARARDAAAWWDSLGFGGRAQRLQQWKGVLTRRLQQLCQVVRDETGKPIADAQLESVLAIEHIAWAAKNARKVLGRKRRPAGLLMSNQAATVEYLPLGVVGVIGPWNYPVFTPLGSIAYALAAGNAVVFKPSEFTPGVGKWLVDAFAEVVPEQPVLQLVTGYGATGAALTRAGVDKIAFTGSTATGKKIMAACAETLTPVVIEAGGKDPVLVDEDADLDAAADATVWGAFSNSGQTCIGVERVYVHERVHDEFVAKVVEKSKAVRAGSDHDAQYGPVTMPSQLKVIKQHITDALSRGGKALVGGADAVGDRYAQPTVLVDVPEDAEAVREETFGPTVTIAKVASMDEAVEKANATRYGLAATVFSKSRGMELARRLRTGMAAINAPLSFAGIASLPFGGVGDSGFGRIHGQEGLREFARTKAIARQRFTAPIALTTFDRKEKTDALVAKLITVMHGKR
>NZ_CP045480.1|WP_153037703.1|9957356_9958439_-|MFS-transporter
MAPLAFTVLTTATTGSYRLGGVMMAVFVVAELAGSVPAGRLLDRIGPSRGLVLFLLCAAAGLGGLAFAASAGASPAVLLVLVVLPGLIAGGLSGGFRALLAGTVSGPLLPRAVSVDAMLIDAVIIGGPLLVALLAGFGAVLPIAAMAVVFAVSALLVPRREAPVPVSGERPPLPIRAAVPWLACQFTIGHLLSTIEVAPFALAQRLGAAEGAAALIITVLSGASIVGGALYAWRGVHLTVSPRAQAITLLGGFIAGGCTVALDLGWPGLLTGVVLIGFCTGPLVTVASVQMQGLLPEGRRSEGFSLTFVVQASGFGLGALTVGVLPLWLAPVFGVASAVLACAILGRGPARVVGTLPATS

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Crispr_ID: NZ_CP045480_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045480_10

10239441-10239586

Orphan

Consensus_repeat	Method
GGCAGGCCGCCACCCAGGATCGCGTC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP045480_10

>merge|NZ_CP045480|10|10239441-10239586|CRISPRCasFinder
GGCAGGCCGCCACCCAGGATCGCGTCCGTCGGCAGCACGCCACCGGTCACGTCACCGGTGGGCAGGCCGCCACCCAGGATCGCGTCGGTGGGCAGGCCACCGCCGAGGATCGCGTCGGTCGGCAGACCGCCACCCAGCAGCGCGTC

>NZ_CP045480|10|10|10239441-10239586|CRISPRCasFinder
GGCAGGCCGCCACCCAGGATCGCGTC	CGTCGGCAGCACGCCACCGGTCACGTCACCGGTG
GGCAGGCCGCCACCCAGGATCGCGTC	GGTGGGCAGGCCACCGCCGAGGATCGCGTCGGTC
GGCAGACCGCCACCCAGCAGCGCGTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045480.1\|WP_153036630.1\|10246347_10246998_+\|response-regulator	unknown	unknown	gnl\|CDD\|225107
NZ_CP045480.1\|WP_153036624.1\|10237018_10237702_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045480.1\|WP_153036632.1\|10250956_10251832_-\|ribokinase	unknown	unknown	gnl\|CDD\|238579
NZ_CP045480.1\|WP_153036633.1\|10252005_10252161_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|367272
NZ_CP045480.1\|WP_153036619.1\|10231536_10232364_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|131480
NZ_CP045480.1\|WP_153037738.1\|10244060_10245212_+\|AI-2E-family-transporter	unknown	unknown	gnl\|CDD\|279875
NZ_CP045480.1\|WP_153036618.1\|10230852_10231533_+\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|367243
NZ_CP045480.1\|WP_153036629.1\|10245208_10246351_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|226951
NZ_CP045480.1\|WP_153036623.1\|10236194_10236959_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187620
NZ_CP045480.1\|WP_153036620.1\|10232360_10232954_-\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|366102
NZ_CP045480.1\|WP_153036617.1\|10229679_10230786_-\|FAD-dependent-monooxygenase	unknown	unknown	gnl\|CDD\|223727
NZ_CP045480.1\|WP_153036621.1\|10234275_10235763_+\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|312032
NZ_CP045480.1\|WP_153036634.1\|10252200_10253865_+\|DUF2339-domain-containing-protein	unknown	unknown	gnl\|CDD\|378390
NZ_CP045480.1\|WP_153037740.1\|10247844_10248462_+\|DUF1707-domain-containing-protein	unknown	unknown	gnl\|CDD\|377959
NZ_CP045480.1\|WP_153036631.1\|10248445_10250092_-\|phosphoenolpyruvate--protein-phosphotransferase	unknown	unknown	gnl\|CDD\|224006
NZ_CP045480.1\|WP_153036625.1\|10237752_10238340_-\|PadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224609
NZ_CP045480.1\|WP_153037739.1\|10247146_10247851_+\|DUF1707-domain-containing-protein	unknown	unknown	gnl\|CDD\|377959
NZ_CP045480.1\|WP_153036622.1\|10235805_10236207_+\|glyoxalase	unknown	unknown	gnl\|CDD\|319943
NZ_CP045480.1\|WP_153036628.1\|10242778_10243735_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045480.1\|WP_153036626.1\|10238452_10239232_+\|dioxygenase	unknown	unknown	gnl\|CDD\|153375

Protein	Function_ID	Function_description	E-value
NZ_CP045480.1\|WP_153036630.1\|10246347_10246998_+\|response-regulator	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	4.60412e-65
NZ_CP045480.1\|WP_153036621.1\|10234275_10235763_+\|alpha/beta-fold-hydrolase	gnl\|CDD\|312032	pfam08386, Abhydrolase_4, TAP-like protein. This is a family of putative bacterial peptidases and hydrolases that bear similarity to a tripeptidyl aminopeptidase isolated from Streptomyces lividans. A member of this family is thought to be involved in the C-terminal processing of propionicin F, a bacteriocidin characterized from Propionibacterium freudenreichii.	7.67805e-14
NZ_CP045480.1\|WP_153036632.1\|10250956_10251832_-\|ribokinase	gnl\|CDD\|238579	cd01174, ribokinase, Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides and histidine, and for entry into the pentose phosphate pathway. Ribokinase is dimeric in solution.	5.8311e-104
NZ_CP045480.1\|WP_153036633.1\|10252005_10252161_-\|hypothetical-protein	gnl\|CDD\|367272	pfam02956, TT_ORF1, TT viral orf 1. TT virus (TTV), isolated initially from a Japanese patient with hepatitis of unknown aetiology, has since been found to infect both healthy and diseased individuals and numerous prevalence studies have raised questions about its role in unexplained hepatitis. ORF1 is a large 750 residue protein. The N-terminal half of this protein corresponds to the capsid protein.	1.82719e-07
NZ_CP045480.1\|WP_153036629.1\|10245208_10246351_+\|ATP-binding-protein	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	1.04167e-23
NZ_CP045480.1\|WP_153036618.1\|10230852_10231533_+\|TetR-family-transcriptional-regulator	gnl\|CDD\|367243	pfam02909, TetR_C, Tetracyclin repressor, C-terminal all-alpha domain.	2.02149e-15
NZ_CP045480.1\|WP_153036619.1\|10231536_10232364_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|131480	TIGR02427, b-ketoadipate_enol-lactone_hydrolase, 3-oxoadipate enol-lactonase. Members of this family are 3-oxoadipate enol-lactonase. Note that the substrate is known as 3-oxoadipate enol-lactone, 2-oxo-2,3-dihydrofuran-5-acetate, 4,5-Dihydro-5-oxofuran-2-acetate, and 5-oxo-4,5-dihydrofuran-2-acetate. The enzyme the catalyzes the fourth step in the protocatechuate degradation to beta-ketoadipate and then to succinyl-CoA and acetyl-CoA. 4-hydroxybenzoate, 3-hydroxybenzoate, and vanillate all can be converted in one step to protocatechuate. This enzyme also acts in catechol degradation. In genomes that catabolize both catechol and protocatechuate, two forms of this enzyme may be found. All members of the seed alignment for this model were chosen from within protocatechuate degradation operons of at least three genes of the pathway, from genomes with the complete pathway through beta-ketoadipate. [Energy metabolism, Other].	1.35468e-30
NZ_CP045480.1\|WP_153036623.1\|10236194_10236959_-\|SDR-family-oxidoreductase	gnl\|CDD\|187620	cd05362, THN_reductase-like_SDR_c, tetrahydroxynaphthalene/trihydroxynaphthalene reductase-like, classical (c) SDRs. 1,3,6,8-tetrahydroxynaphthalene reductase (4HNR) of Magnaporthe grisea and the related 1,3,8-trihydroxynaphthalene reductase (3HNR) are typical members of the SDR family containing the canonical glycine rich NAD(P)-binding site and active site tetrad, and function in fungal melanin biosynthesis. This subgroup also includes an SDR from Norway spruce that may function to protect against both biotic and abitoic stress. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	6.98642e-79
NZ_CP045480.1\|WP_153037738.1\|10244060_10245212_+\|AI-2E-family-transporter	gnl\|CDD\|279875	pfam01594, AI-2E_transport, AI-2E family transporter. This family includes four different proteins from E. coli alone. One of them, YdgG or TqsA, has been shown to mediate transport of the quorum-sensing signal autoinducer 2 (AI-2). It is not clear if TqsA enhances secretion of AI-2 or inhibits AI-2 uptake. By altering the intracellular concentration of AI-2, TqsA affects gene expression in biofilms and biofilm formation. TsqA belongs to the AI-2 exporter (AI-2E) superfamily.	5.922e-52
NZ_CP045480.1\|WP_153036617.1\|10229679_10230786_-\|FAD-dependent-monooxygenase	gnl\|CDD\|223727	COG0654, UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion].	1.05502e-28
NZ_CP045480.1\|WP_153036634.1\|10252200_10253865_+\|DUF2339-domain-containing-protein	gnl\|CDD\|378390	pfam10101, DUF2339, Predicted membrane protein (DUF2339). This domain, found in various hypothetical bacterial proteins, has no known function.	1.02822e-11
NZ_CP045480.1\|WP_153036620.1\|10232360_10232954_-\|TetR-family-transcriptional-regulator	gnl\|CDD\|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	1.91898e-11
NZ_CP045480.1\|WP_153037740.1\|10247844_10248462_+\|DUF1707-domain-containing-protein	gnl\|CDD\|377959	pfam08044, DUF1707, Domain of unknown function (DUF1707). This domain is found in a variety of Actinomycetales proteins. All of the proteins containing this domain are hypothetical and probably membrane bound or associated. Currently, it is unclear to the function of this domain.	4.31426e-17
NZ_CP045480.1\|WP_153036631.1\|10248445_10250092_-\|phosphoenolpyruvate--protein-phosphotransferase	gnl\|CDD\|224006	COG1080, PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism].	3.4239e-174
NZ_CP045480.1\|WP_153036625.1\|10237752_10238340_-\|PadR-family-transcriptional-regulator	gnl\|CDD\|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	1.6894e-08
NZ_CP045480.1\|WP_153037739.1\|10247146_10247851_+\|DUF1707-domain-containing-protein	gnl\|CDD\|377959	pfam08044, DUF1707, Domain of unknown function (DUF1707). This domain is found in a variety of Actinomycetales proteins. All of the proteins containing this domain are hypothetical and probably membrane bound or associated. Currently, it is unclear to the function of this domain.	5.81642e-19
NZ_CP045480.1\|WP_153036622.1\|10235805_10236207_+\|glyoxalase	gnl\|CDD\|319943	cd08355, TioX_like, Micromonospora sp. TioX and similar proteins. Micromonospora sp. TioX is encoded by a gene of the thiocoraline biosynthetic gene cluster. Thiocoraline is a thiodepsipeptide with potent antitumor activity. TioX may be involved in thiocoraline resistance or secretion. TioX belongs to vicinal oxygen chelate (VOC) superfamily that is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	7.00248e-39
NZ_CP045480.1\|WP_153036626.1\|10238452_10239232_+\|dioxygenase	gnl\|CDD\|153375	cd07363, 45_DOPA_Dioxygenase, The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine. This subfamily is composed of plant 4,5-DOPA Dioxygenase, the uncharacterized Escherichia coli protein Jw3007, and similar proteins. 4,5-DOPA Dioxygenase catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine (4,5-DOPA). The reaction results in the opening of the cyclic ring between carbons 4 and 5 and producing an unstable seco-DOPA that rearranges to betalamic acid. 4,5-DOPA Dioxygenase is a key enzyme in the biosynthetic pathway of the plant pigment betalain. Homologs of DODA are present not only in betalain-producing plants but also in bacteria and archaea. This enzyme is a member of the class III extradiol dioxygenase family, a group of enzymes which use a non-heme Fe(II) to cleave aromatic rings between a hydroxylated carbon and an adjacent non-hydroxylated carbon.	2.40571e-107

>NZ_CP045480.1|WP_153036626.1|10238452_10239232_+|dioxygenase
MTAAPVLYLSHGAPPLADDVTWTRQLADLSAGLARPTAILIVSAHWEEAPLTIGATTTVPLIYDFWGFPDRYYQVEYRAPGAPALAEKVRKLLRSAETPVHDDPARGLDHGAYVPLVEMFPDADVPVLQISMPSLDPVRLFELGRRLAPLRDEGVLIIGSGFFTHNLSGLNMHRDADHEPPAWSAEFDDWGAQVLAKNDVDAILDFTHKAPAPSLAHPRIEHFAPLFVSLGAGGEAGGAPKTVIDGFWYGLAKRSVQLD
>NZ_CP045480.1|WP_153036625.1|10237752_10238340_-|PadR-family-transcriptional-regulator
MSATRLLVLGAVRGFGRAHGYLVRTELLTWGADEWANVKWGSLYHALRQLAKDGLLRAIDVPDSGGRVDYEITEAGDEEFFRLLREALRQPELRQDMLTAGLALLPALPRAEAVELLEKRLHALESGRADIVEQTSTWADPGHVQELFDLWVHNATSGVDWTRGLIDRLKAGAHTMAGEDPAGFGMPGTWTPTQV
>NZ_CP045480.1|WP_153036624.1|10237018_10237702_-|hypothetical-protein
MRTLLPGAVSLLLAPPLLLAGVLLRLPHDLFFPAQLAAYASGPGRMFAAYSCFLLGVVALWPGILLLAHRIGGGFGLWGGVLALFGLFARAFHAGVDHLAFQLVRVLGQDTATRVIADSYGAYHVLRVCTVPMIFGWVVLAIGAWRSRALGRVGAVALGAMTAMPVGVLKGTEWLSVVAAVGLCVALVPLGVRVLRECRWPAPAVVVRWSVVGAGSVAAMYFLGQAG
>NZ_CP045480.1|WP_153036623.1|10236194_10236959_-|SDR-family-oxidoreductase
MELTGKTALVTGASRGIGRAVAERLAGAGALVAVHYGSNDAAAKDTVESIERAGGKAFAVRAELGVDGDVDTLFAGLERGLAGRPLDILVNNAAIVSGKLDEVTPVEFDRLFAVNVRAPYFIVQRALPLLADNGRVINVSSGVTRIAFPETAYAMSKGALDAFGRNLANQLGDRGITVNTVAPGVTETDMNSWLADEPDRGNAVAAMSALGRIGRPSDVAAAVALLASPDAGWITGNWLDASGGLFLGPRPQAG
>NZ_CP045480.1|WP_153036622.1|10235805_10236207_+|glyoxalase
MTTTASLHAYFGYRDAQGALDWFQRAFGFEQTMAYPDDHGGIAHAELRYGTGVSFSLFTDEAGYDRAALKGETVGHGLYLRLGSNEEVDALYAKATAAGAKVIWQPEATEWGTYRFRVHDPEGYEWTFGTYPA
>NZ_CP045480.1|WP_153036621.1|10234275_10235763_+|alpha/beta-fold-hydrolase
MKKLGALVAAVAVGGATLLAGTAAADNGLSRFHHQELDWKACDHKALDEAGAQCADVEVPLNYAEPRGRTISVAISRIKATDPGKRRGVMLSNPGGPGGPGLDMTLGIREAMTPEVRAQYDLIGMDPRGIGRSNPVDCGWPVGLMLRSPGVDRAAFDRTVRLEADLARQCADTEGDLLRHISTRNTARDMDVIRGALGESKINYFGWSYGTYLGSVYTQMFPRQSDRFVLDSAVDSKRYGTRMFQDMGAPNEAALDEWAEWTAERDSEYHLGTTGKQVRALVEDLVQRSAKQPIRIGEYEVDQHALPIVLFMSLADPRANPALATDVRQLVDAADGKQVEPNPALKNTLEVMYRPTPETQLSGQAAVLCGDKVEHRDPEYYWRNIERTRAEQPLFGAFANGISACAFWGPPAEKATVVRNSVPALIVQTTGDTRTSYESGVDLHRSMKGSKLVTLQDVRVHAVFGNFPNSCAENAVNTYFADGTLPATDLTCRAD
>NZ_CP045480.1|WP_153036620.1|10232360_10232954_-|TetR-family-transcriptional-regulator
MTRMTRAQQQQRTHERLLEAGSAVFERRGFLAATVEEIVAEAGYTRGALYKHFEGKEGLWLAITEARAEEHILDLGARLDLVADRDELVAALVPAGPAFGEDVPRWSVATYEFSAWLAGQPELAATVVDTQRQREERIAELLERTCARLGVRPALPLPQVVVLIGALGGSLALRRAVDPATDVHAVASGTIAAVFGA
>NZ_CP045480.1|WP_153036619.1|10231536_10232364_-|alpha/beta-fold-hydrolase
MSVRFTRNGNVEIAYETFGSAPGRPLLLIQGAGAPMLGWADEFCEALVERGFHVARCDNRDAGRSSRATRPYTVADMATDGLAVLDALGWPAAHVAGISLGGMIGQVMAARHPDRVLSLTSMCSAPDASVRRTKLGFLLRYFALNWRKPAGPDAAGERLVKLHRLLGSTGHPRDEEWLRRIGREGHAHRTDAAAGRRQAAAARASGDRRAELATITAPTLVLSGEADPVQPPRAGRATADAIPGARFVSHPGMGHDLPPALWPAIIDDIDKIASA
>NZ_CP045480.1|WP_153036618.1|10230852_10231533_+|TetR-family-transcriptional-regulator
MLVWERPEPPERPAPAPLSRERIVRAAIRLADANGLDAVSLRKVAAALDVGPMRLYGYIATKEELLDLMLDAVHAEIRPVGGNWREVLRSLAETTRRTAHQHEWLADLLGGRPQLGPNTLAGGEAVLAAMDGVDLDTVVPAVAAVNAYVVGAVRREITEQRAERSSGMDKRQWQTTYGPYLERTFATGRFPALATVVRDGPHLDADETFLAGLEFLLDGIEARISN
>NZ_CP045480.1|WP_153036617.1|10229679_10230786_-|FAD-dependent-monooxygenase
MDIAIVGAGPGGLALARVLHVNGIDAVVYEREPSRDARGQGGMLDIHSGQRALREAGLIDQFFAIARGAGQDMRLLEPDGTLLLQEDTPDDAPLARPEVDRADLRALLLDSLPDGVVRWGHAFESAGDGVLRFADGRSASYDLLVGADGAQSRVRPLVTDARPVHIGQNVVEIGIPDIDRTHPDLAAMVGRGNYWVLGDGLSLAAQRNGDGRVRIGISFYRTGEDWFATSGIPFDDPAAAKARLIDLLPGWDARFVALIEACDDTIAARSITTLPIGLTWPSKPDVTLVGDAAHLMPPVGEGANMALLDGAQLGLALVAHPDDIPAAVEKYEREMFDRAGAAARMSADIQEMLMSPNASKKMLAFFQP
>NZ_CP045480.1|WP_153036628.1|10242778_10243735_-|hypothetical-protein
MAEVAANQRGAKRAGRWTSRALLVAGGVLAGTAAAWAFATGASAAEAPTAPAAPETDTAGLTPVTDATVQGLDDLTGGVSELSGDTAGAAARATEVPSTGSSRAVGEDVTAAVDQFTSEAVVRPVERTLGAFEHIARQPEDAPKVIEQTLTPANQGVQDFGKKFWDFLQPRGEDALAELPRLPFGGADQVVPEQPVTVVPEAGTVGIHTVGVPAGPHDGSWLAAFDASRAGGGITDEGDAGDRELPSPFSPLRAPLAPLTVPTVPGGGNSAGGHFDGLLIGVPAGSAAAFDTAPIGSVRSGVRHLMVEPGAQPGVTPD
>NZ_CP045480.1|WP_153037738.1|10244060_10245212_+|AI-2E-family-transporter
MPVELDVTTVVPRGLRIGAALAWRFLVVIAALYVIVWLVGYLSVVVIPLSIALLLAALMAPGVGWLVKAGLPRGLAAGIVLIGGLGLLGGLLTFVVAQFTSGLPALQQQLTESLDQIQDWLVNGPLHLRQTQIQDFINQAVDFLKKNQATITDSALTTAGTVGEVLTGFVLTLFILIFFLAGGEQIWTFLTRGVPRQVRNRVDVAGRRGFASLVSYVRATAAVAVVDAVGIGIGLWILGVPLVIPLATLVFLGAFVPIIGAVLTGAVAVLVALVTNGFVTALIVLGVVILVMQLESHILQPLLLGRAVKLHPLAVVLAITAGLVAAGIAGALLAVPLLAVLNSGIKSLLHERDPDPAAVDVLEDQSAEPNTKAPDDDGAEPAK
>NZ_CP045480.1|WP_153036629.1|10245208_10246351_+|ATP-binding-protein
MTARFGPTTRDLASPLWWGAIGLRVLTWVFAAGIGVVHQDEYRRAWLAWTVLGVMAIWTVLTSLVYAREALRWRWRWLVVADVGLTACLVLTSPWILSDAQLAAADPLITTVWAAVPPLVAGARFGAVGGLAGGLVIALCTGAARAEFTVDVARDGVLLLASGLLIGMTASTARRSGSALAQALRTEAATAERERLARSIHDSVLQVLARVRKRGAELGGEAAELAELAGEQEIALRALVTTEPTRPTDETADLRAALQLLGTSTVHISGPAGPVSLPAHVTTELADAVREALANVAKHAEGAQAWVLLEDLGDEVVVSVRDDGPGIPAGRLERARAEGRLGVAKSIQDRVTGLGGTISLDTAPGAGTEWEIRVPKGASG
>NZ_CP045480.1|WP_153036630.1|10246347_10246998_+|response-regulator
MSAISVMVVDDHPIWRDGVARDLGEHGFEVLATAPDGDAAIRIAKTVRPDVVLMDMNLGETSGVDATRAITGALPETRVLVLSASGEHEDVLEAVKAGASGYLVKSASSAELAEAVRRTAAGDPVFTAGLAGLVLGEYRRMADAPPTIGEPPRLTERETDVLRQVAKGLTARQIAEKLVISHRTVENHVQSTLRKLQLHNRVELARYAIEHGLDSD
>NZ_CP045480.1|WP_153037739.1|10247146_10247851_+|DUF1707-domain-containing-protein
MNTVPEESEAAAAAPEAASPPAPKEFSARDLRVSDAEREHVVGVLQKAIGRGMLDLDEFTERTDKALASRTRGELNSVLADLPGLVHRDAAPVLATGAAPAPAPQYAPAPQYAPPSGTPLELRAHGSNLKRSGQWQVPSHLRVRNKYASTKLDFTEAVLTSPVVYIELDTKWGGVELVVPEEAGVDLNAITEVKWGSVEDKRKRQPASGSPTIIVTGRVHGGPLVVRNGRRSRW
>NZ_CP045480.1|WP_153037740.1|10247844_10248462_+|DUF1707-domain-containing-protein
MVSDRELRVSDAERDHVAALLQKAVGQGLLDLEEFTARTDLALAARTRGELNRVLTDLPGLVHHGVNGTVPARRDRLVLRTLMGGTRRTGHWRVPHEILVQNQMGSTELDFTEAEFSQAEVRIELSVAAGSVELLLPATASLSTSDVKIRAGTLTDRTEFDRAAGKPRFVLSGSVFAGSVEIRTPRYYRFGRVQVRLPWRVTWGS
>NZ_CP045480.1|WP_153036631.1|10248445_10250092_-|phosphoenolpyruvate--protein-phosphotransferase
MSSTKLSGVAVSPGRASGPVVRVAEPLGAPPSTPAPPDPAAEAARVEPAAQLVAARLEKQAETATGEAATILQTTAAMAADPTLVSQAEALVKNERLPAARAVHQAAEGFAEMLAAAGGYLAERVRDIHDIRDRIVAELLGLAPPGVPELTGPSVLVARDLAPADTAGLDPAKVLALVTEEGGPTSHTAILARALGIPAVVAVRGLLAVEAEALLVDGDTGEVEPVDASAPVLAATTNGPAEWDGTGVTADGHRVKVLGNVGSAADAQSAADAGAEGVGLFRTEFCYLDASTEPTVEAQRAAYAAVLSPFKDKPVIVRTLDAGADKPLAFLSPDTEPNPALGVRGLRIAFDRPEILDRQLEAIALAAQDSGAEVSVMAPMVATAAEAAWFAERVHAAGITRAGVMIEIPAAALAAREILDAVDFVSIGTNDLAQYTFAADRQLGAVAALNDPWQPALLRLIALIGEAAAATGKPAGVCGEAAADPQLARVLTGLGLTSLSMNAAAVRAVGASLAAVTRAECEAVADAALAAADPAAARQAVSAVTSPR
>NZ_CP045480.1|WP_153036632.1|10250956_10251832_-|ribokinase
MTAEVLVAGSINADLVVSADRRPGAGETVLGGDTVLLPGGKGANTAVAASLIGADVAMVGAVGDDANGRLLLNSLREAGVSVDLVRTVDRPTGAAYIVVTPDGENSILVSPGANSALEPSALDGAFDGARVLAVSMEIPLPTVEHAVIAAAEAGVRVLLNLSPVAKVSPRTLKAVDVLLVNEHEAAWLLGTEGTQADPRGLLELGPHSAVLTRGAEGALVITADEVVEVASPKVEAVDTTGAGDAFTGALAASLADGANLPDAARLAVKVAAISVTRPGAQPSYPRAGELD
>NZ_CP045480.1|WP_153036633.1|10252005_10252161_-|hypothetical-protein
MLRCLGRGGRRRRGGRRRRVRRRRRHRRRRRFDWRRRAVRGRWQSAQFLAE
>NZ_CP045480.1|WP_153036634.1|10252200_10253865_+|DUF2339-domain-containing-protein
MPPPVMPPPAMPPFPMPRWQPQPQPPKVTLADKLAKDGAGSKVLAWIGGAVTLLGVVLLLVLAIQRGWVGPVPRVLLGAALGGTLAGLGVWLHRNPAARTGAFALAATGVAVLYADIVAATAFLELVPSWAGLLLGLVVAVGGLALAGYWKAHGLAVFVLLGCAVCAPVLTSGLTVSLMTFLLILAVAAAPIQLTREWPGVVLAAGLPPVAGSALTVSFAAGAWFETGPEIGVAVLAVLTSLLVLATATATTALHRADVTPIGLLAVAPLPTMLLPFLLDRPLAAAFTGGLTAVLAGLWIGGRKRLPSGVSMTAGVLASLLAFETTAVALSGETQVIVVLAEAIALAAVAIRLKSKGMVAAGAAFGVAGLLTAMATVATPVLLLLPLRTGPATDGLITAAVVSPLIALAAVLVAVAAFHTGAAKSAAPLVNIFAGMAVLYGAAGTVLYPVRLLVDGQLGFLIGHALITVSWTVAALVLLLRGIRRKAFRITGLVLVAAALAKLVLFDLSSLDGIARVGAFLGAGLVLLAAGTRYARLVSATRSAQDTASGSMRM

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP045480_9	9.1\|9943607\|26\|NZ_CP045480\|CRISPRCasFinder	9943607-9943632	26	NZ_CP023721	Rhodococcus sp. H-CA8f plasmid unnamed, complete sequence	152128-152153	3	0.885
NZ_CP045480_9	9.1\|9943607\|26\|NZ_CP045480\|CRISPRCasFinder	9943607-9943632	26	MT310894	Microbacterium phage Tempo, complete genome	43104-43129	4	0.846
NZ_CP045480_9	9.1\|9943607\|26\|NZ_CP045480\|CRISPRCasFinder	9943607-9943632	26	NZ_CP022424	Vitreoscilla filiformis strain ATCC 15551 plasmid pVF1, complete sequence	222570-222595	4	0.846
NZ_CP045480_9	9.1\|9943607\|26\|NZ_CP045480\|CRISPRCasFinder	9943607-9943632	26	NZ_CP040937	Hymenobacter sp. DG01 plasmid unnamed, complete sequence	28756-28781	4	0.846
NZ_CP045480_9	9.1\|9943607\|26\|NZ_CP045480\|CRISPRCasFinder	9943607-9943632	26	NZ_CP029990	Salmonella enterica subsp. diarizonae serovar 48:i:z strain SA20121591 plasmid pSA20121591.1, complete sequence	70114-70139	4	0.846
NZ_CP045480_9	9.1\|9943607\|26\|NZ_CP045480\|CRISPRCasFinder	9943607-9943632	26	NZ_CP029356	Azospirillum sp. CFH 70021 plasmid unnamed1	772040-772065	4	0.846
NZ_CP045480_9	9.1\|9943607\|26\|NZ_CP045480\|CRISPRCasFinder	9943607-9943632	26	NZ_CP006588	Hymenobacter sp. APR13 plasmid pHA, complete sequence	15756-15781	4	0.846
NZ_CP045480_9	9.1\|9943607\|26\|NZ_CP045480\|CRISPRCasFinder	9943607-9943632	26	MT889397	Mycobacterium phage OfUltron, complete genome	9808-9833	4	0.846
NZ_CP045480_9	9.1\|9943607\|26\|NZ_CP045480\|CRISPRCasFinder	9943607-9943632	26	MT889396	Mycobacterium phage Seabastian, complete genome	9808-9833	4	0.846
NZ_CP045480_9	9.1\|9943607\|26\|NZ_CP045480\|CRISPRCasFinder	9943607-9943632	26	KY290953	Aeromonas phage 51, complete genome	5155-5180	4	0.846
NZ_CP045480_9	9.1\|9943607\|26\|NZ_CP045480\|CRISPRCasFinder	9943607-9943632	26	MK359307	Mycobacterium phage Ochi17, complete genome	9808-9833	4	0.846
NZ_CP045480_9	9.1\|9943607\|26\|NZ_CP045480\|CRISPRCasFinder	9943607-9943632	26	MK813942	Aeromonas phage 4_4512, complete genome	33438-33463	4	0.846
NZ_CP045480_9	9.1\|9943607\|26\|NZ_CP045480\|CRISPRCasFinder	9943607-9943632	26	MN428051	Mycobacterium phage Modragons, complete genome	9808-9833	4	0.846
NZ_CP045480_9	9.1\|9943607\|26\|NZ_CP045480\|CRISPRCasFinder	9943607-9943632	26	NC_028923	Mycobacterium phage Llama, complete genome	9808-9833	4	0.846
NZ_CP045480_9	9.1\|9943607\|26\|NZ_CP045480\|CRISPRCasFinder	9943607-9943632	26	NC_019527	Aeromonas phage vB_AsaM-56, complete genome	5155-5180	4	0.846
NZ_CP045480_9	9.1\|9943607\|26\|NZ_CP045480\|CRISPRCasFinder	9943607-9943632	26	KY290954	Aeromonas phage 56, complete genome	5155-5180	4	0.846
NZ_CP045480_9	9.1\|9943607\|26\|NZ_CP045480\|CRISPRCasFinder	9943607-9943632	26	NZ_LR134465	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 23, complete sequence	409263-409288	5	0.808
NZ_CP045480_9	9.1\|9943607\|26\|NZ_CP045480\|CRISPRCasFinder	9943607-9943632	26	NC_008757	Polaromonas naphthalenivorans CJ2 plasmid pPNAP01, complete sequence	216051-216076	5	0.808
NZ_CP045480_9	9.1\|9943607\|26\|NZ_CP045480\|CRISPRCasFinder	9943607-9943632	26	NZ_CP035507	Haematobacter massiliensis strain OT1 plasmid pOT1-7, complete sequence	63179-63204	5	0.808
NZ_CP045480_9	9.1\|9943607\|26\|NZ_CP045480\|CRISPRCasFinder	9943607-9943632	26	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	446307-446332	5	0.808
NZ_CP045480_9	9.1\|9943607\|26\|NZ_CP045480\|CRISPRCasFinder	9943607-9943632	26	NZ_CP029358	Azospirillum sp. CFH 70021 plasmid unnamed3	96408-96433	5	0.808
NZ_CP045480_9	9.1\|9943607\|26\|NZ_CP045480\|CRISPRCasFinder	9943607-9943632	26	NZ_CP035227	Bacillus subtilis strain SRCM103517 plasmid unnamed1	16920-16945	5	0.808
NZ_CP045480_9	9.1\|9943607\|26\|NZ_CP045480\|CRISPRCasFinder	9943607-9943632	26	KX196154	Shewanella phage SFCi1, complete genome	28078-28103	5	0.808
NZ_CP045480_9	9.1\|9943607\|26\|NZ_CP045480\|CRISPRCasFinder	9943607-9943632	26	NC_048098	Arthrobacter phage Andrew, complete genome	5535-5560	5	0.808
NZ_CP045480_9	9.1\|9943607\|26\|NZ_CP045480\|CRISPRCasFinder	9943607-9943632	26	MK479295	Salmonella phage SEE-1, complete genome	22615-22640	6	0.769
NZ_CP045480_9	9.1\|9943607\|26\|NZ_CP045480\|CRISPRCasFinder	9943607-9943632	26	MT012729	Salmonella phage vB_SenTO17, complete genome	32701-32726	6	0.769
NZ_CP045480_9	9.1\|9943607\|26\|NZ_CP045480\|CRISPRCasFinder	9943607-9943632	26	MK214385	Salmonella phage TS6, complete genome	20179-20204	6	0.769
NZ_CP045480_9	9.1\|9943607\|26\|NZ_CP045480\|CRISPRCasFinder	9943607-9943632	26	NZ_CP044989	Deinococcus sp. AJ005 plasmid p380k, complete sequence	349412-349437	6	0.769
NZ_CP045480_5	5.5\|6519311\|32\|NZ_CP045480\|CRISPRCasFinder	6519311-6519342	32	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	1043103-1043134	7	0.781
NZ_CP045480_5	5.5\|6519311\|32\|NZ_CP045480\|CRISPRCasFinder	6519311-6519342	32	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	770022-770053	7	0.781
NZ_CP045480_9	9.1\|9943607\|26\|NZ_CP045480\|CRISPRCasFinder	9943607-9943632	26	NC_029106	Achromobacter phage phiAxp-2, complete genome	34316-34341	7	0.731
NZ_CP045480_10	10.1\|10239467\|34\|NZ_CP045480\|CRISPRCasFinder	10239467-10239500	34	NZ_CP046906	Streptomyces sp. QHH-9511 plasmid unnamed, complete sequence	32394-32427	7	0.794
NZ_CP045480_10	10.2\|10239527\|34\|NZ_CP045480\|CRISPRCasFinder	10239527-10239560	34	MT723937	Gordonia phage JKSyngboy, complete genome	37959-37992	8	0.765
NZ_CP045480_10	10.1\|10239467\|34\|NZ_CP045480\|CRISPRCasFinder	10239467-10239500	34	NZ_CP012182	Pseudonocardia sp. EC080610-09 plasmid pBCI2-1, complete sequence	634912-634945	9	0.735
NZ_CP045480_10	10.1\|10239467\|34\|NZ_CP045480\|CRISPRCasFinder	10239467-10239500	34	NZ_CP010990	Pseudonocardia sp. EC080625-04 plasmid pFRP1-1, complete sequence	274869-274902	9	0.735
NZ_CP045480_10	10.1\|10239467\|34\|NZ_CP045480\|CRISPRCasFinder	10239467-10239500	34	NZ_CP012185	Pseudonocardia sp. EC080619-01 plasmid pBCI1-2, complete sequence	412493-412526	9	0.735
NZ_CP045480_10	10.1\|10239467\|34\|NZ_CP045480\|CRISPRCasFinder	10239467-10239500	34	NC_017311	Desulfovibrio vulgaris RCH1 plasmid pDEVAL01, complete sequence	20876-20909	9	0.735
NZ_CP045480_10	10.1\|10239467\|34\|NZ_CP045480\|CRISPRCasFinder	10239467-10239500	34	NC_005863	Desulfovibrio vulgaris str. Hildenborough plasmid pDV, complete sequence	26320-26353	9	0.735
NZ_CP045480_10	10.2\|10239527\|34\|NZ_CP045480\|CRISPRCasFinder	10239527-10239560	34	NZ_CP016287	Rhizobium leguminosarum strain Vaf10 plasmid unnamed1, complete sequence	106781-106814	9	0.735
NZ_CP045480_1	1.1\|722747\|34\|NZ_CP045480\|CRISPRCasFinder	722747-722780	34	NZ_LR134470	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 28, complete sequence	29883-29916	10	0.706
NZ_CP045480_5	5.5\|6519311\|32\|NZ_CP045480\|CRISPRCasFinder	6519311-6519342	32	NZ_CP053565	Pseudonocardia sp. Gen01 plasmid unnamed1, complete sequence	34691-34722	10	0.688
NZ_CP045480_10	10.2\|10239527\|34\|NZ_CP045480\|CRISPRCasFinder	10239527-10239560	34	NC_009621	Sinorhizobium medicae WSM419 plasmid pSMED02, complete sequence	910992-911025	11	0.676

1. spacer 9.1|9943607|26|NZ_CP045480|CRISPRCasFinder matches to NZ_CP023721 (Rhodococcus sp. H-CA8f plasmid unnamed, complete sequence) position: , mismatch: 3, identity: 0.885

cctacggccagcagcaacagcagccg	CRISPR spacer
cgtacggccagcagcctcagcagccg	Protospacer
* *************  *********

2. spacer 9.1|9943607|26|NZ_CP045480|CRISPRCasFinder matches to MT310894 (Microbacterium phage Tempo, complete genome) position: , mismatch: 4, identity: 0.846

cctacggccagcagcaacagcagccg	CRISPR spacer
gcggcggccagcagcaacagcagcag	Protospacer
 * .******************** *

3. spacer 9.1|9943607|26|NZ_CP045480|CRISPRCasFinder matches to NZ_CP022424 (Vitreoscilla filiformis strain ATCC 15551 plasmid pVF1, complete sequence) position: , mismatch: 4, identity: 0.846

cctacggccagcagcaacagcagccg	CRISPR spacer
gctgcgcccagcagcaacagcagcgg	Protospacer
 **.** ***************** *

4. spacer 9.1|9943607|26|NZ_CP045480|CRISPRCasFinder matches to NZ_CP040937 (Hymenobacter sp. DG01 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.846

cctacggccagcagcaacagcagccg	CRISPR spacer
gccacggccagcagcagcagcagcgg	Protospacer
 *.*************.******* *

5. spacer 9.1|9943607|26|NZ_CP045480|CRISPRCasFinder matches to NZ_CP029990 (Salmonella enterica subsp. diarizonae serovar 48:i:z strain SA20121591 plasmid pSA20121591.1, complete sequence) position: , mismatch: 4, identity: 0.846

cctacggccagcagcaacagcagccg	CRISPR spacer
cggatggccagctgcaacagcagccg	Protospacer
*  *.******* *************

6. spacer 9.1|9943607|26|NZ_CP045480|CRISPRCasFinder matches to NZ_CP029356 (Azospirillum sp. CFH 70021 plasmid unnamed1) position: , mismatch: 4, identity: 0.846

cctacggccagcagcaacagcagccg	CRISPR spacer
cgcacggccagcagccgcagcagccg	Protospacer
* .************ .*********

7. spacer 9.1|9943607|26|NZ_CP045480|CRISPRCasFinder matches to NZ_CP006588 (Hymenobacter sp. APR13 plasmid pHA, complete sequence) position: , mismatch: 4, identity: 0.846

cctacggccagcagcaacagcagccg	CRISPR spacer
gccacggccagcagcagcagcagcgg	Protospacer
 *.*************.******* *

8. spacer 9.1|9943607|26|NZ_CP045480|CRISPRCasFinder matches to MT889397 (Mycobacterium phage OfUltron, complete genome) position: , mismatch: 4, identity: 0.846

cctacggccagcagcaacagcagccg	CRISPR spacer
cagacggcccgcagcaacatcagccg	Protospacer
*  ****** ********* ******

9. spacer 9.1|9943607|26|NZ_CP045480|CRISPRCasFinder matches to MT889396 (Mycobacterium phage Seabastian, complete genome) position: , mismatch: 4, identity: 0.846

cctacggccagcagcaacagcagccg	CRISPR spacer
cagacggcccgcagcaacatcagccg	Protospacer
*  ****** ********* ******

10. spacer 9.1|9943607|26|NZ_CP045480|CRISPRCasFinder matches to KY290953 (Aeromonas phage 51, complete genome) position: , mismatch: 4, identity: 0.846

cctacggccagcagcaacagcagccg	CRISPR spacer
cacaaggccagcagcaacagcagcgg	Protospacer
* .* ******************* *

11. spacer 9.1|9943607|26|NZ_CP045480|CRISPRCasFinder matches to MK359307 (Mycobacterium phage Ochi17, complete genome) position: , mismatch: 4, identity: 0.846

cctacggccagcagcaacagcagccg	CRISPR spacer
cagacggcccgcagcaacatcagccg	Protospacer
*  ****** ********* ******

12. spacer 9.1|9943607|26|NZ_CP045480|CRISPRCasFinder matches to MK813942 (Aeromonas phage 4_4512, complete genome) position: , mismatch: 4, identity: 0.846

cctacggccagcagcaacagcagccg	CRISPR spacer
cacaaggccagcagcaacagcagcgg	Protospacer
* .* ******************* *

13. spacer 9.1|9943607|26|NZ_CP045480|CRISPRCasFinder matches to MN428051 (Mycobacterium phage Modragons, complete genome) position: , mismatch: 4, identity: 0.846

cctacggccagcagcaacagcagccg	CRISPR spacer
cagacggcccgcagcaacatcagccg	Protospacer
*  ****** ********* ******

14. spacer 9.1|9943607|26|NZ_CP045480|CRISPRCasFinder matches to NC_028923 (Mycobacterium phage Llama, complete genome) position: , mismatch: 4, identity: 0.846

cctacggccagcagcaacagcagccg	CRISPR spacer
cagacggcccgcagcaacatcagccg	Protospacer
*  ****** ********* ******

15. spacer 9.1|9943607|26|NZ_CP045480|CRISPRCasFinder matches to NC_019527 (Aeromonas phage vB_AsaM-56, complete genome) position: , mismatch: 4, identity: 0.846

cctacggccagcagcaacagcagccg	CRISPR spacer
cacaaggccagcagcaacagcagcgg	Protospacer
* .* ******************* *

16. spacer 9.1|9943607|26|NZ_CP045480|CRISPRCasFinder matches to KY290954 (Aeromonas phage 56, complete genome) position: , mismatch: 4, identity: 0.846

cctacggccagcagcaacagcagccg	CRISPR spacer
cacaaggccagcagcaacagcagcgg	Protospacer
* .* ******************* *

17. spacer 9.1|9943607|26|NZ_CP045480|CRISPRCasFinder matches to NZ_LR134465 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 23, complete sequence) position: , mismatch: 5, identity: 0.808

cctacggccagcagcaacagcagccg	CRISPR spacer
gcgacggccagcaggaacagcagcac	Protospacer
 * *********** *********

18. spacer 9.1|9943607|26|NZ_CP045480|CRISPRCasFinder matches to NC_008757 (Polaromonas naphthalenivorans CJ2 plasmid pPNAP01, complete sequence) position: , mismatch: 5, identity: 0.808

cctacggccagcagcaacagcagccg	CRISPR spacer
gtaaaggcccgcagcaacagcagccg	Protospacer
 . * **** ****************

19. spacer 9.1|9943607|26|NZ_CP045480|CRISPRCasFinder matches to NZ_CP035507 (Haematobacter massiliensis strain OT1 plasmid pOT1-7, complete sequence) position: , mismatch: 5, identity: 0.808

cctacggccagcagcaacagcagccg	CRISPR spacer
gcgacggccagcggcaacagcagcgc	Protospacer
 * *********.***********

20. spacer 9.1|9943607|26|NZ_CP045480|CRISPRCasFinder matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.808

cctacggccagcagcaacagcagccg	CRISPR spacer
acggcggccagcagcaccagcagcca	Protospacer
 * .************ ********.

21. spacer 9.1|9943607|26|NZ_CP045480|CRISPRCasFinder matches to NZ_CP029358 (Azospirillum sp. CFH 70021 plasmid unnamed3) position: , mismatch: 5, identity: 0.808

cctacggccagcagcaacagcagccg	CRISPR spacer
aggacggccagcagcatcagcggccg	Protospacer
   ************* ****.****

22. spacer 9.1|9943607|26|NZ_CP045480|CRISPRCasFinder matches to NZ_CP035227 (Bacillus subtilis strain SRCM103517 plasmid unnamed1) position: , mismatch: 5, identity: 0.808

cctacggccagcagcaacagcagccg	CRISPR spacer
aaaacgtccagctgcaacagcagccg	Protospacer
   *** ***** *************

23. spacer 9.1|9943607|26|NZ_CP045480|CRISPRCasFinder matches to KX196154 (Shewanella phage SFCi1, complete genome) position: , mismatch: 5, identity: 0.808

cctacggccagcagcaacagcagccg	CRISPR spacer
cccaaggccagcagcaacagcagaac	Protospacer
**.* ******************

24. spacer 9.1|9943607|26|NZ_CP045480|CRISPRCasFinder matches to NC_048098 (Arthrobacter phage Andrew, complete genome) position: , mismatch: 5, identity: 0.808

cctacggccagcagcaacagcagccg	CRISPR spacer
agcacggccagcagcggcagcagccg	Protospacer
  .************..*********

25. spacer 9.1|9943607|26|NZ_CP045480|CRISPRCasFinder matches to MK479295 (Salmonella phage SEE-1, complete genome) position: , mismatch: 6, identity: 0.769

cctacggccagcagcaacagcagccg	CRISPR spacer
agccagcccagcagcaacagcagccg	Protospacer
  .  * *******************

26. spacer 9.1|9943607|26|NZ_CP045480|CRISPRCasFinder matches to MT012729 (Salmonella phage vB_SenTO17, complete genome) position: , mismatch: 6, identity: 0.769

cctacggccagcagcaacagcagccg	CRISPR spacer
agccagcccagcagcaacagcagccg	Protospacer
  .  * *******************

27. spacer 9.1|9943607|26|NZ_CP045480|CRISPRCasFinder matches to MK214385 (Salmonella phage TS6, complete genome) position: , mismatch: 6, identity: 0.769

cctacggccagcagcaacagcagccg	CRISPR spacer
agccagcccagcagcaacagcagccg	Protospacer
  .  * *******************

28. spacer 9.1|9943607|26|NZ_CP045480|CRISPRCasFinder matches to NZ_CP044989 (Deinococcus sp. AJ005 plasmid p380k, complete sequence) position: , mismatch: 6, identity: 0.769

cctacggccagcagcaacagcagccg	CRISPR spacer
cagacggccagcagcaacagcacggc	Protospacer
*  *******************

29. spacer 5.5|6519311|32|NZ_CP045480|CRISPRCasFinder matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 7, identity: 0.781

ctgcga-ttgacccggctggtgctgtccaggcg	CRISPR spacer
-ggcgagaagacccggctggtgctggccgggct	Protospacer
  ****   **************** **.***

30. spacer 5.5|6519311|32|NZ_CP045480|CRISPRCasFinder matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 7, identity: 0.781

ctgcga-ttgacccggctggtgctgtccaggcg	CRISPR spacer
-ggcgagaagacccggctggtgctggccgggct	Protospacer
  ****   **************** **.***

31. spacer 9.1|9943607|26|NZ_CP045480|CRISPRCasFinder matches to NC_029106 (Achromobacter phage phiAxp-2, complete genome) position: , mismatch: 7, identity: 0.731

cctacggccagcagcaacagcagccg	CRISPR spacer
gtggcggccagcagcaacagcaggtt	Protospacer
 . .******************* .

32. spacer 10.1|10239467|34|NZ_CP045480|CRISPRCasFinder matches to NZ_CP046906 (Streptomyces sp. QHH-9511 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cgtcggcagc-acgccaccggtcacgtcaccggtg	CRISPR spacer
-gtcacccatgacgccaccggtcacgtcaccagtg	Protospacer
 ***. * .. ********************.***

33. spacer 10.2|10239527|34|NZ_CP045480|CRISPRCasFinder matches to MT723937 (Gordonia phage JKSyngboy, complete genome) position: , mismatch: 8, identity: 0.765

ggtgggcaggccaccgccgaggatcgcgtcggtc	CRISPR spacer
ctcgaacaggccaccgccggggatcgcgtaggcc	Protospacer
  .*..*************.********* **.*

34. spacer 10.1|10239467|34|NZ_CP045480|CRISPRCasFinder matches to NZ_CP012182 (Pseudonocardia sp. EC080610-09 plasmid pBCI2-1, complete sequence) position: , mismatch: 9, identity: 0.735

-----cgtcggcagcacgccaccggtcacgtcaccggtg	CRISPR spacer
gaggacaccg-----acgccaccgggcacgtcgccggtg	Protospacer
     *..**     ********** ******.******

35. spacer 10.1|10239467|34|NZ_CP045480|CRISPRCasFinder matches to NZ_CP010990 (Pseudonocardia sp. EC080625-04 plasmid pFRP1-1, complete sequence) position: , mismatch: 9, identity: 0.735

-----cgtcggcagcacgccaccggtcacgtcaccggtg	CRISPR spacer
gaggacaccg-----acgccaccgggcacgtcgccggtg	Protospacer
     *..**     ********** ******.******

36. spacer 10.1|10239467|34|NZ_CP045480|CRISPRCasFinder matches to NZ_CP012185 (Pseudonocardia sp. EC080619-01 plasmid pBCI1-2, complete sequence) position: , mismatch: 9, identity: 0.735

-----cgtcggcagcacgccaccggtcacgtcaccggtg	CRISPR spacer
gaggacaccg-----acgccaccgggcacgtcgccggtg	Protospacer
     *..**     ********** ******.******

37. spacer 10.1|10239467|34|NZ_CP045480|CRISPRCasFinder matches to NC_017311 (Desulfovibrio vulgaris RCH1 plasmid pDEVAL01, complete sequence) position: , mismatch: 9, identity: 0.735

cgtcggcagcacgccaccggtcacgtcaccggtg	CRISPR spacer
cgcacccggcacgccaccgggctcgtcaccggac	Protospacer
**.   *.************ * *********

38. spacer 10.1|10239467|34|NZ_CP045480|CRISPRCasFinder matches to NC_005863 (Desulfovibrio vulgaris str. Hildenborough plasmid pDV, complete sequence) position: , mismatch: 9, identity: 0.735

cgtcggcagcacgccaccggtcacgtcaccggtg	CRISPR spacer
cgcacccggcacgccaccgggctcgtcaccggac	Protospacer
**.   *.************ * *********

39. spacer 10.2|10239527|34|NZ_CP045480|CRISPRCasFinder matches to NZ_CP016287 (Rhizobium leguminosarum strain Vaf10 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.735

ggtgggc-aggccaccgccgaggatcgcgtcggtc	CRISPR spacer
-atggatgaggccaacgccgaggatcgtgtcgtag	Protospacer
 .***.. ****** ************.****

40. spacer 1.1|722747|34|NZ_CP045480|CRISPRCasFinder matches to NZ_LR134470 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 28, complete sequence) position: , mismatch: 10, identity: 0.706

cgccgggcggggcgggtagtcggacgcgggtgtc	CRISPR spacer
atccgggcggggcgggtgggcggacgaatgggga	Protospacer
  ***************.* ****** . * *

41. spacer 5.5|6519311|32|NZ_CP045480|CRISPRCasFinder matches to NZ_CP053565 (Pseudonocardia sp. Gen01 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

ctgcgattgacccggctggtgctgtccaggcg	CRISPR spacer
taggagatgacgcggctggtgctgtcccggga	Protospacer
. * .. **** *************** ** .

42. spacer 10.2|10239527|34|NZ_CP045480|CRISPRCasFinder matches to NC_009621 (Sinorhizobium medicae WSM419 plasmid pSMED02, complete sequence) position: , mismatch: 11, identity: 0.676

ggtgggcaggccaccgccgaggatcgcgtcggtc	CRISPR spacer
cagccgcaggccaccgccgacgatctcgtgcgga	Protospacer
 .   *************** **** ***  *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

10172595 : 10197684

Streptomyces_phage(61.11%)

capsid,portal,terminase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_153036561.1\|10172595_10173858_+\|terminase	PBSX family phage terminase large subunit	A0A1J0MC69	Streptomyces_phage	1.3e-119	54.0
WP_153036562.1\|10173817_10174096_-	hypothetical protein	NA	NA	NA	NA
WP_153036563.1\|10174129_10175728_+\|portal	phage portal protein	A0A1J0MCN7	Streptomyces_phage	1.1e-107	45.2
WP_153036564.1\|10175699_10177769_+	hypothetical protein	A0A1J0MCS2	Streptomyces_phage	7.9e-58	30.3
WP_153036565.1\|10177756_10178017_+	hypothetical protein	NA	NA	NA	NA
WP_153036566.1\|10178013_10178679_-	hypothetical protein	NA	NA	NA	NA
WP_153036567.1\|10178675_10178891_-	hypothetical protein	NA	NA	NA	NA
WP_153036568.1\|10179026_10179698_+	hypothetical protein	A0A1J0MD42	Streptomyces_phage	2.3e-22	45.8
WP_153036569.1\|10179715_10180720_+\|capsid	phage capsid protein	G9FH86	Rhodococcus_phage	1.8e-153	82.6
WP_153036570.1\|10180719_10181004_+	hypothetical protein	G9FH87	Rhodococcus_phage	1.9e-07	50.9
WP_153036571.1\|10181073_10181499_+	hypothetical protein	NA	NA	NA	NA
WP_153036572.1\|10181489_10181819_+	hypothetical protein	NA	NA	NA	NA
WP_153036573.1\|10181833_10182178_+	hypothetical protein	G9FH91	Rhodococcus_phage	6.8e-15	48.4
WP_153036574.1\|10182174_10182603_+	hypothetical protein	NA	NA	NA	NA
WP_153036575.1\|10182629_10183139_+	hypothetical protein	NA	NA	NA	NA
WP_153036576.1\|10183138_10183684_+	hypothetical protein	A0A0U4JH92	Gordonia_phage	2.1e-10	29.4
WP_153036577.1\|10183866_10186263_+	hypothetical protein	A0A0S2MU35	Streptomyces_phage	8.6e-16	30.0
WP_153036578.1\|10186262_10187147_+	hypothetical protein	A0A1J0MCF9	Streptomyces_phage	4.9e-33	36.7
WP_153036579.1\|10187162_10188362_+	hypothetical protein	NA	NA	NA	NA
WP_153036580.1\|10188385_10189495_+	hypothetical protein	A0A1J0MCX4	Streptomyces_phage	4.7e-41	31.9
WP_153036581.1\|10189494_10190244_+	hypothetical protein	NA	NA	NA	NA
WP_153037729.1\|10190329_10190701_+	hypothetical protein	A0A0R8VA19	Thermobifida_phage	2.3e-16	40.8
WP_153036582.1\|10190705_10191719_+	lysozyme	A0A068F1N1	Mycobacterium_phage	2.7e-27	36.3
WP_153036583.1\|10191721_10192030_+	hypothetical protein	NA	NA	NA	NA
WP_153036584.1\|10192033_10192384_+	hypothetical protein	NA	NA	NA	NA
WP_153036585.1\|10192370_10192673_+	hypothetical protein	NA	NA	NA	NA
WP_153036586.1\|10192686_10193730_+	hypothetical protein	A0A142K917	Gordonia_phage	7.0e-47	36.5
WP_153036587.1\|10193729_10194347_+	hypothetical protein	NA	NA	NA	NA
WP_153036588.1\|10194355_10194817_-	NUDIX domain-containing protein	A0A0M4RQ80	Streptomyces_phage	3.2e-36	53.3
WP_153036589.1\|10194888_10195530_-	dTMP kinase	A0A0M4QTT3	Streptomyces_phage	1.3e-38	47.3
WP_153036590.1\|10195526_10196987_-	radical SAM protein	A0A0M4R1U9	Streptomyces_phage	1.9e-175	64.8
WP_153037730.1\|10196964_10197684_-	hypothetical protein	A0A0M4RBB7	Streptomyces_phage	3.8e-44	44.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP045480

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection