CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP040310	Escherichia coli strain 21B8 plasmid pO157, complete sequence	0 crisprs	NA	0	0	1	0
NZ_CP040309	Escherichia coli strain 21B8 chromosome, complete genome	6 crisprs	c2c9_V-U4,cas3,DEDDh,DinG,PrimPol,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,PD-DExK	1	8	14	1

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

8201 : 58244

Macacine_betaherpesvirus(45.45%)

protease,transposase,integrase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001034097.1\|8201_12104_+\|protease	serine protease autotransporter EspP	Q9LA58	Enterobacterial_phage	5.5e-238	40.4
WP_071525077.1\|13500_13680_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_001302199.1\|14281_15103_+	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_000975743.1\|15102_16209_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_000550559.1\|16298_18020_+	phosphoethanolamine transferase CptA	NA	NA	NA	NA
WP_001302181.1\|18093_19092_+	lauroyl-Kdo(2)-lipid IV(A) myristoyltransferase	NA	NA	NA	NA
WP_072141201.1\|19964_22661_+\|protease	metalloprotease StcE	NA	NA	NA	NA
WP_001302175.1\|22747_23623_+	type II secretion system protein GspC	NA	NA	NA	NA
WP_001449993.1\|23680_25591_+	variant type II secretion system secretin EtpD	NA	NA	NA	NA
WP_000092338.1\|25590_27096_+	type II secretion system protein GspE	NA	NA	NA	NA
WP_001173152.1\|27097_28321_+	type II secretion system protein GspF	NA	NA	NA	NA
WP_000082929.1\|28781_29336_+	type II secretion system protein GspH	NA	NA	NA	NA
WP_000173396.1\|29350_29698_+	type II secretion system protein GspI	NA	NA	NA	NA
WP_000082782.1\|29694_30294_+	type II secretion system protein GspJ	NA	NA	NA	NA
WP_000776550.1\|30290_31268_+	general secretion pathway protein GspK	NA	NA	NA	NA
WP_071525076.1\|31306_32479_+	type II secretion system protein GspL	NA	NA	NA	NA
WP_001004187.1\|32465_32978_+	type II secretion system protein M	NA	NA	NA	NA
WP_000096786.1\|33035_33869_+	prepilin peptidase	NA	NA	NA	NA
WP_000971918.1\|33960_34362_+	lipoprotein, PulS/OutS family	NA	NA	NA	NA
WP_000839950.1\|36252_36768_+	enterohemolysin-activating lysine-acyltransferase EhxC	NA	NA	NA	NA
WP_000217739.1\|36769_39766_+	enterohemolysin EhxA	NA	NA	NA	NA
WP_000987091.1\|39815_41936_+	enterohemolysin T1SS ABC transporter permease/ATPase EhxB	W8CYL7	Bacillus_phage	7.1e-46	30.2
WP_001213545.1\|41939_43379_+	enterohemolysin T1SS ABC transporter subunit EhxD	NA	NA	NA	NA
WP_001303402.1\|43445_43640_+	hypothetical protein	NA	NA	NA	NA
WP_001358890.1\|43669_43954_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_010891288.1\|44122_44353_+	hypothetical protein	NA	NA	NA	NA
WP_001066920.1\|44473_45214_+\|integrase	site-specific integrase	I3WFA4	Macacine_betaherpesvirus	2.0e-24	57.6
WP_000361615.1\|45498_46476_-	RepB family plasmid replication initiator protein	J9Q7H0	Salmonella_phage	5.1e-100	58.9
WP_000708307.1\|46883_47084_-	hypothetical protein	NA	NA	NA	NA
WP_001248529.1\|47080_47701_-	hypothetical protein	NA	NA	NA	NA
WP_010891291.1\|47697_48381_-	DNA-binding protein	NA	NA	NA	NA
WP_000813634.1\|48839_49058_+	type II toxin-antitoxin system antitoxin CcdA	NA	NA	NA	NA
WP_001159868.1\|49059_49365_+	type II toxin-antitoxin system toxin CcdB	NA	NA	NA	NA
WP_000016989.1\|49365_50172_+\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	3.7e-56	99.1
WP_077631973.1\|50848_50929_-	AMP nucleosidase	A0A0N7BTS3	Escherichia_phage	1.5e-07	100.0
WP_085948178.1\|50894_52108_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_000852148.1\|52183_52939_+	replication initiation protein RepE	I3WF20	Macacine_betaherpesvirus	1.1e-142	99.6
WP_000772446.1\|53526_54693_+	plasmid-partitioning protein SopA	A0A2I6B2X3	Macacine_betaherpesvirus	7.0e-229	100.0
WP_000817031.1\|54692_55664_+	ParB/RepB/Spo0J family plasmid partition protein	I3WF22	Macacine_betaherpesvirus	4.8e-175	100.0
WP_000273919.1\|56272_57175_+	DUF1281 domain-containing protein	NA	NA	NA	NA
WP_010891292.1\|57178_57484_+	hypothetical protein	NA	NA	NA	NA
WP_000085945.1\|57560_58244_+	DNA methylase	A0A2I7RE86	Vibrio_phage	8.7e-30	37.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP040309

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP040309_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040309_1

592838-592987

Orphan

Consensus_repeat	Method
CGCGTCTTATCAGGCCTACGAGTTCGGTGCTGTGTAGGTCGGATAAGGCGTTCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040309_1

>merge|NZ_CP040309|1|592838-592987|CRISPRCasFinder
CGCGTCTTATCAGGCCTACGAGTTCGGTGCTGTGTAGGTCGGATAAGGCGTTCATGCCGCATCCGACAATAACAGCATTGCCTGATGCGACGCTTGCGCGTCTTATCAGGCCTACGAGTTCAGTGCTGTGTAGGTCGGATAAGGCGTTCA

>NZ_CP040309|1|1|592838-592987|CRISPRCasFinder
CGCGTCTTATCAGGCCTACGAGTTCGGTGCTGTGTAGGTCGGATAAGGCGTTCA	TGCCGCATCCGACAATAACAGCATTGCCTGATGCGACGCTTG
CGCGTCTTATCAGGCCTACGAGTTCAGTGCTGTGTAGGTCGGATAAGGCGTTCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040309.1\|WP_001059397.1\|587424_587928_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP040309.1\|WP_000079623.1\|588120_589317_+\|DUF898-domain-containing-protein	unknown	unknown	gnl\|CDD\|226719
NZ_CP040309.1\|WP_000446132.1\|604406_604979_-\|Polarity-suppression-protein	unknown	unknown	gnl\|CDD\|311413
NZ_CP040309.1\|WP_000786399.1\|592226_592670_-\|DNA-polymerase-III-subunit-chi	unknown	unknown	gnl\|CDD\|235581
NZ_CP040309.1\|WP_000500712.1\|581906_582620_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|183714
NZ_CP040309.1\|WP_001294533.1\|597144_598647_-\|DUF853-domain-containing-protein	unknown	unknown	gnl\|CDD\|283518
NZ_CP040309.1\|WP_000397144.1\|593023_594535_-\|leucyl-aminopeptidase	unknown	unknown	gnl\|CDD\|234863
NZ_CP040309.1\|WP_000416407.1\|589371_592227_-\|valine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235582
NZ_CP040309.1\|WP_000256678.1\|582690_583284_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|366102
NZ_CP040309.1\|WP_001295681.1\|595901_596984_+\|LPS-export-ABC-transporter-permease-LptG	unknown	unknown	gnl\|CDD\|237900
NZ_CP040309.1\|WP_000012925.1\|585796_586801_-\|ornithine-carbamoyltransferase	unknown	unknown	gnl\|CDD\|179587
NZ_CP040309.1\|WP_000036491.1\|584003_585740_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040309.1\|WP_001301967.1\|598776_599796_-\|NADPH-dependent-aldehyde-reductase-Ahr	unknown	unknown	gnl\|CDD\|176186
NZ_CP040309.1\|WP_000936844.1\|601682_601988_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP040309.1\|WP_000584114.1\|594801_595902_+\|LPS-export-ABC-transporter-permease-LptF	unknown	unknown	gnl\|CDD\|185075
NZ_CP040309.1\|WP_000002953.1\|586962_587379_+\|ribonuclease-E-inhibitor-RraB	unknown	unknown	gnl\|CDD\|236876
NZ_CP040309.1\|WP_000772662.1\|600240_601515_+\|DUF4102-domain-containing-protein	unknown	unknown	gnl\|CDD\|170049
NZ_CP040309.1\|WP_001453880.1\|602064_602799_+\|type-II-restriction-endonuclease	unknown	unknown	unknown
NZ_CP040309.1\|WP_000095622.1\|602836_604081_-\|DNA-cytosine-methyltransferase	unknown	unknown	gnl\|CDD\|223348
NZ_CP040309.1\|WP_000583470.1\|583428_583881_+\|DUF386-domain-containing-protein	unknown	unknown	gnl\|CDD\|225345

Protein	Function_ID	Function_description	E-value
NZ_CP040309.1\|WP_001059397.1\|587424_587928_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	3.52162e-19
NZ_CP040309.1\|WP_000079623.1\|588120_589317_+\|DUF898-domain-containing-protein	gnl\|CDD\|226719	COG4269, COG4269, Predicted membrane protein [Function unknown].	5.35185e-152
NZ_CP040309.1\|WP_000446132.1\|604406_604979_-\|Polarity-suppression-protein	gnl\|CDD\|311413	pfam07455, Psu, Phage polarity suppression protein (Psu). This family contains a number of phage polarity suppression proteins (Psu) (approximately 190 residues long). The Psu protein of bacteriophage P4 causes suppression of transcriptional polarity in Escherichia coli by overcoming Rho termination factor activity.	5.7343e-53
NZ_CP040309.1\|WP_000786399.1\|592226_592670_-\|DNA-polymerase-III-subunit-chi	gnl\|CDD\|235581	PRK05728, PRK05728, DNA polymerase III subunit chi; Validated.	5.53743e-66
NZ_CP040309.1\|WP_000500712.1\|581906_582620_-\|SDR-family-oxidoreductase	gnl\|CDD\|183714	PRK12742, PRK12742, SDR family oxidoreductase.	2.19644e-150
NZ_CP040309.1\|WP_001294533.1\|597144_598647_-\|DUF853-domain-containing-protein	gnl\|CDD\|283518	pfam05872, DUF853, Bacterial protein of unknown function (DUF853). This family consists of several bacterial proteins of unknown function. BMEI1370 is thought to be an ATPase.	0
NZ_CP040309.1\|WP_000397144.1\|593023_594535_-\|leucyl-aminopeptidase	gnl\|CDD\|234863	PRK00913, PRK00913, multifunctional aminopeptidase A; Provisional.	0
NZ_CP040309.1\|WP_000416407.1\|589371_592227_-\|valine--tRNA-ligase	gnl\|CDD\|235582	PRK05729, valS, valyl-tRNA synthetase; Reviewed.	0
NZ_CP040309.1\|WP_000256678.1\|582690_583284_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	9.63528e-10
NZ_CP040309.1\|WP_001295681.1\|595901_596984_+\|LPS-export-ABC-transporter-permease-LptG	gnl\|CDD\|237900	PRK15071, PRK15071, lipopolysaccharide ABC transporter permease; Provisional.	0
NZ_CP040309.1\|WP_000012925.1\|585796_586801_-\|ornithine-carbamoyltransferase	gnl\|CDD\|179587	PRK03515, PRK03515, ornithine carbamoyltransferase subunit I; Provisional.	0
NZ_CP040309.1\|WP_001301967.1\|598776_599796_-\|NADPH-dependent-aldehyde-reductase-Ahr	gnl\|CDD\|176186	cd05283, CAD1, Cinnamyl alcohol dehydrogenases (CAD). Cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family, reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	5.44918e-169
NZ_CP040309.1\|WP_000936844.1\|601682_601988_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	2.8494e-12
NZ_CP040309.1\|WP_000584114.1\|594801_595902_+\|LPS-export-ABC-transporter-permease-LptF	gnl\|CDD\|185075	PRK15120, PRK15120, lipopolysaccharide ABC transporter permease LptF; Provisional.	0
NZ_CP040309.1\|WP_000002953.1\|586962_587379_+\|ribonuclease-E-inhibitor-RraB	gnl\|CDD\|236876	PRK11191, PRK11191, ribonuclease E inhibitor RraB.	4.50628e-69
NZ_CP040309.1\|WP_000772662.1\|600240_601515_+\|DUF4102-domain-containing-protein	gnl\|CDD\|170049	PRK09692, PRK09692, integrase; Provisional.	8.97279e-83
NZ_CP040309.1\|WP_000095622.1\|602836_604081_-\|DNA-cytosine-methyltransferase	gnl\|CDD\|223348	COG0270, Dcm, Site-specific DNA methylase [DNA replication, recombination, and repair].	4.0359e-78
NZ_CP040309.1\|WP_000583470.1\|583428_583881_+\|DUF386-domain-containing-protein	gnl\|CDD\|225345	COG2731, EbgC, Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism].	3.50239e-70

>NZ_CP040309.1|WP_000786399.1|592226_592670_-|DNA-polymerase-III-subunit-chi
MKNATFYLLDNDTTVDGLSAVEQLVCEIAAERWRSGKRVLIACEDEKQAYRLDEALWARPAESFVPHNLAGEGPRGGAPVEIAWPQKRSSSPRDILISLRTSFADFATAFTEVVDFVPYEDSLKQLARERYKAYRVAGFNLNTATWK
>NZ_CP040309.1|WP_000416407.1|589371_592227_-|valine--tRNA-ligase
MEKTYNPQDIEQPLYEHWEKQGYFKPNGDESQESFCIMIPPPNVTGSLHMGHAFQQTIMDTMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTRHDYGREAFIDKIWEWKAESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRLYKEDLIYRGKRLVNWDPKLRTAISDLEVENRESKGSMWHIRYPLADGAKTADGKDYLVVATTRPETLLGDTGVAVNPEDPRYKDLIGKYVILPLVNRRIPIVGDEHADMEKGTGCVKITPAHDFNDYEVGKRHALPMINILTFDGDIRESAQVFDTKGNESDVYSSEIPAEFQKLERFAARKAVVAAVDALGLLEEIKPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKPAVEAVENGDIQFVPKQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDEAGNVYVGRNEEEVRKENNLGADVALRQDEDVLDTWFSSALWTFSTLGWPENTDALRQFHPTSVMVSGFDIIFFWIARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQKMSKSKGNVIDPLDMVDGISLPELLEKRTGNMMQPQLADKIRKRTEKQFPNGIEPHGTDALRFTLAALASTGRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGFNGGEMTLSLADRWILAEFNQTIKAYREALDSFRFDIAAGILYEFTWNQFCDWYLELTKPVMNGGTEAELRGTRHTLVTVLEGLLRLAHPIIPFITETIWQRVKVLCGITADTIMLQPFPQYDASQVDEAALADTEWLKQAIVAVRNIRAEMNIAPGKPLELLLRGCSADAERRVNENRGFLQTLARLESITVLPADDKGPVSVTKIIDGAELLIPMAGLINKEDELARLAKEVAKIEGEISRIENKLANEGFVARAPEAVIAKEREKLEGYAEAKAKLIEQQAVIAAL
>NZ_CP040309.1|WP_000079623.1|588120_589317_+|DUF898-domain-containing-protein
MAQVINEMDVPSHSFVFHGTGERYFLICVVNVLLTIITLGIYLPWALMKCKRYLYANMEVNGQRFSYGITGGNVFFSCLVFVFFYFAILMTVSADMPLIGCVLTLSLLVLLIFMAAKGLRYQALMTSLNGVRFSFNCSMKGVWWVTFFLPILMAIGMGTVFFISTKMLHANSSSSVIVSVVLMAIVGIVSIGIFNGTLYSLVMSFLWSNTSFGIHRFKVKLDTAYCIKYAILAFLALLPFLAVAGYIIFDQILNAYDSSVYANDDIENLQQFMEMQRKMIIAQLIYYFGIAVSTSYLTVSLRNHFMSNLSLNDGRIRFRSTLTYHGMLYRMCALVVISGITGGLAYPLLKIWMIDWQAKNTYLLGDLDDLPLINKEEQPDKGFLASISRGIMPSLPFL
>NZ_CP040309.1|WP_001059397.1|587424_587928_-|GNAT-family-N-acetyltransferase
MNNIAPQSPVMRRLTLQDNPAIARVIRQVSAEYGLTADKGYTVADPNLDELYQVYSQPGHAYWVVEYEGEVVGGGGIAPLAGSESDICELQKMYFLPAIRGKGLAKKLALKAMEEAREMGFKRCYLETTAFLKEAIGLYEHLGFQHIDYALGCTGHVDCEVRMLREL
>NZ_CP040309.1|WP_000002953.1|586962_587379_+|ribonuclease-E-inhibitor-RraB
MANPEQLEEQREETRLIIEELLEDGSDPDALYTIEHHLSADDLETLEKAAVEAFKLGYEVTDPEELEVEDGDIVICCDILSECALNADLIDAQVEQLMTLAEKFDVEYDGWGTYFEDPNGEDGDDEDFVDEDDDGVRH
>NZ_CP040309.1|WP_000012925.1|585796_586801_-|ornithine-carbamoyltransferase
MSGFYHKHFLKLLDFTPAELNSLLQLAAKLKADKKSGKEEAKLTGKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPSGSQIGHKESIKDTARVLGRMYDGIQYRGYGQEIVETLAEYAGVPVWNGLTNEFHPTQLLADLLTMQEHLPGKPFNEMTLVYAGDARNNMGNSMLEAAALTGLDLRLVAPQACWPEAALVTECRALAQQNGGNITLTEDVAKGVEGADFIYTDVWVSMGEAKEKWAERIALLRDYQVNSKMMQLTGNPEVKFLHCLPAFHDDQTTLGKKMAEEFGLHGGMEVTDEVFESAASIVFDQAENRMHTIKAVMVATLSK
>NZ_CP040309.1|WP_000036491.1|584003_585740_+|hypothetical-protein
MSKISDLNYSQHITLADNFKQKSEVLNTWRVGMNNFARNAGGQDNTRNILNPKTFLEFLVKIFTLGYVDFSKRSNEAGRNMMAHIESSSYIKNNDGSEIMKFVMNNPEGERADSPKVIIEISLSTITTMGTRQGHTAIIFPQPDGSTNRYERKSFERKDESSLHLITNKVLACYQREANKEIARLLNNHQKLNNLQKLNNLQKLNNIQKLNNIQELNNSQELNNSQELNNSQDLKNSQVSCKGSVDFTITDLLEKSLNNALLAIRNEHLLLMPHVCSESISYLLGENGILEEIDKLYELNDHGIDNDKEGNNEINDIMINLSHILIESLDDAKVNLTPVIHSMLMTFLELPYNNDVKILEWCFNKSMQYFDDSAKIEHACSVINHINFRRDQSKVAETLFFNLDKEPYKNSPELQELIWKKLVVYVNDFNLSNREKTYLIQRIFNNVESLFNKVPVSILVNDIFMNDFFMKNTEMINWYFPRLLKSYEDEKIYFDKLGYNFNNKESNEEIMKNQPKDVIEEKLNNELKLRFRMMQTILKSEVNVSPFIDQQRLNTLNPPENLRIAIEKFGWKKKTITA
>NZ_CP040309.1|WP_000583470.1|583428_583881_+|DUF386-domain-containing-protein
MIIGNIHNLQPWLPQELRQAIEHIKAHVTAETPKGKHDIEGNRLFYLISEDMTEPYEARRAEYHARYLDIQIVLKGQEGMTFSTQPAGTPDTDWLADKDIAFLPEGVDEKTVILNEGDFVVFYPGEVHKPLCAVGAPAQVRKAVVKMLMA
>NZ_CP040309.1|WP_000256678.1|582690_583284_+|TetR/AcrR-family-transcriptional-regulator
MVTKKQSRVPGRPRRFAPEQAVSAAKVLFHQKGFDAVSVAEVTDYLGINPPSLYAAFGSKAGLFSRVLNEYVGTEAIPLVDILRDDRPVGECLAEVLKEAARRYSQNGGCAGCMVLEGIHSHDPQARDIAVQYYHAAETAIYDYIARLHPQSAQCVTDFMSTVMSGLSAKAREGHSLEQLCATAALAGEAIKTILKE
>NZ_CP040309.1|WP_000500712.1|581906_582620_-|SDR-family-oxidoreductase
MGAFTGKTVLILGGSRGIGAAIVRRFVTDGANVRFTYAGSKDAAERLAQETGATAVFTDSADRDAVIDVVRKSGALDILVVNAGIGVFGDALELNADDIDRLFKINIHAPYHASVEAARQMPEGGRILIIGSVNGDRMPVAGMAAYAASKSALQGMARGLARDFGPRGITINVVQPGPIDTDANPANGPMRDMLHSFMAIKRHGQPEEVAGMVAWLAGPEASFVTGAMHTIDGAFGA
>NZ_CP040309.1|WP_000397144.1|593023_594535_-|leucyl-aminopeptidase
MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFNVPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNVITRVIGEQQMKELGMHSYLAVGQGSQNESLMSVIEYKGNASEDARPIVLVGKGLTFDSGGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVLAGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMANHNPLAHELIAASEQSGDRAWRLPLGDEYQEQLESNFADMANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLAQFLLNRAGFNGEE
>NZ_CP040309.1|WP_000584114.1|594801_595902_+|LPS-export-ABC-transporter-permease-LptF
MIIIRYLVRETLKSQLAILFILLLIFFCQKLVRILGAAVDGDIPANLVLSLLGLGVPEMAQLILPLSLFLGLLMTLGKLYTESEITVMHACGLSKAVLVKAAMILAVFTAIVAAVNVMWAGPWSSRHQDEVLAEAKANPGMAALAQGQFQQATNGSSVLFIESVDGSDFKDVFLAQIRPKGNARPSVVVADSGHLTQLRDGSQVVTLNQGTRFEGTALLRDFRITDFQDYQAIIGHQAVALDPNDTDQMDMRTLWNTDTDRARAELNWRITLVFTVFMMALMVVPLSVVNPRQGRVLSMLPAMLLYLLFFLIQTSLKSNGGKGKLDPTLWMWTVNLIYLALAIVLNLWDTVPVRRLRASFSRKGAV
>NZ_CP040309.1|WP_001295681.1|595901_596984_+|LPS-export-ABC-transporter-permease-LptG
MQPFGVLDRYIGKTIFTTIMMTLFMLVSLSGIIKFVDQLKKAGQGSYDALGAGMYTLLSVPKDVQIFFPMAALLGALLGLGMLAQRSELVVMQASGFTRMQVALSVMKTAIPLVLLTMAIGEWVAPQGEQMARNYRAQAMYGGSLLSTQQGLWAKDGNNFVYIERVKGDEELGGISIYAFNENRRLQSVRYAATAKFDPEHKVWRLSQVDESDLTNPKQITGSQTVSGTWKTNLTPDKLGVVALDPDALSISGLHNYVKYLKSSGQDAGRYQLNMWSKIFQPLSVAVMMLMALSFIFGPLRSVPMGVRVVTGISFGFVFYVLDQIFGPLTLVYGIPPIIGALLPSASFFLISLWLLMRKS
>NZ_CP040309.1|WP_001294533.1|597144_598647_-|DUF853-domain-containing-protein
MSEPLLIARTPDTELFLLPGMANRHGLITGATGTGKTVTLQKLAESLSEIGVPVFMADVKGDLTGIAQAGTASEKLLARLKNIDVNDWQPHANPVVVWDIFGEKGHSVRATVSDLGPLLLARLLNLNDVQSGVLNIIFRIADDQGLLLLDFKDLRAITQYIGDNAKSFQNQYGNISSASVGAIQRGLLSLEQQGAAHFFGEPMLDIKDWMRTDANGKGVINILSAEKLYQMPKLYAASLLWMLSELYEQLPEAGDLEKPKLVFFFDEAHLLFNDAPQVLLDKIEQVIRLIRSKGVGVWFVSQNPSDIPDNVLGQLGNRVQHALRAFTPKDQKAVKAAAQTMRANPAFDTEKAIQELGTGEALISFLDAKGSPSVVERAMVIAPCSRMGPVTEDERNGLINHSPVYGKYEDEVDRESAYEMLQKGFQASTEQQNNPPAKGKEVAVDDGILGGLKDILFGTTGPRGGKKDGVVQTMAKSAARQVTNQIVRGMLGSLLGGRRR
>NZ_CP040309.1|WP_001301967.1|598776_599796_-|NADPH-dependent-aldehyde-reductase-Ahr
MSMIKSYAAKEAGGELEVYEYDPGELRPQDVEVQVDYCGICHSDLSMIDNEWGFSQYPLVAGHEVIGRVVALGSAAQDKGLQVGQRVGIGWTARSCGHCDACISGNQINCEQGAVPTIMNRGGFAEKLRADWQWVIPLPENIDIESAGPLLCGGITVFKPLLMHHITATSRVGVIGIGGLGHIAIKLLHAMGCEVTAFSSNPAKEQEVLAMGADKVVNSRDPQALKALSGQFDLIINTVNVSLDWQPYFEALTYGGNFHTVGAVLTPLPVPAFTLIAGDRSVSGSATGTPYELRKLMRFAARSKVAPTTELFPMSKINDAIKHVRDGKARYRVVLKADF
>NZ_CP040309.1|WP_000772662.1|600240_601515_+|DUF4102-domain-containing-protein
MKLNARQVETAKPKDKSYKMADGGGLYLEVSAKGSKYWRMKYRRPSDKKEDRLAFGVWPTVTLAEARTRRDEAKKLLAQGIDPKAVQKEAQAENAGAYNFETIAREWHASNKRWSEDHRARVLRYLELYIFPYIGLSDIRQLKTSHLLAPIKKVDASGKHDVAQRLQQRVTAIMRYAVQNDYIDSNPASDMAGALSTAKTRHYPALPSHRFPEFLARLAAYRGRMMTKIAVELSLLTFVRSSELRFARWDEFDFDKSLWRIPAKREEIKGVRYSYRGMKMKEEHLVPLSRQAIGLLEQLKQISGDKTLLFPGDHDATKVMSENTVNNALRAMGYDTKTEVCGHGFRTMARGALGESGLWSDDAIERQLSHSERNNVRAAYIHTSEHLDERRLMVQWWADYLYSNREKHISAFEFANKLNKNSLD
>NZ_CP040309.1|WP_000936844.1|601682_601988_+|helix-turn-helix-transcriptional-regulator
MLPIRLKKARLNAGLTQEQLGILVGIDECSASARMNQYEKGKHMPDFSLTKKIADLLNVPVSYFYTPEDDLAEIILLINKLDKKQRLILLKNLSDGFISHE
>NZ_CP040309.1|WP_001453880.1|602064_602799_+|type-II-restriction-endonuclease
MSETMSINPFMTPFIFDYHSLNDFDELVEAIIAKHLMTGHDTGFGKLIDEKILPRVFGAYKLDKSYRAANEPFIHPCFDEIDHVIQRDDGRIELLSLKAGKWTIQLTMAVQLNKAFHEIINNYPGVADNIVVGVFYGNSHGLTDKYRILRGINTGANHNVIDIRDKVHVYAGKEFWSWLNNGEAETQHWVLEGIERAVKEADIKEKNKDLIEKFKEHVAKKYNEQVLNADGTAQWHKLLEMINE
>NZ_CP040309.1|WP_000095622.1|602836_604081_-|DNA-cytosine-methyltransferase
MSSKKFISLFSGAMGLDLGLEEAGFELVACVEQDKAALKTIKTNKPNLAVFEGSIVDCTGSELLALAGVNDKEEIDLVAGGPPCQAFSVFGNRLGLEDARGQLIFEYVRMIKELNPKVFVMENVRGLLSMSIVPASKKKELSGTIAASAFEKGSLIKRVANEFNKLGYHVDCFVVNAANYGAPQIRERVILIGNRFGMIANFASPLFSNRVEDNLPPFKTLGDVIGPESGFVDKYPEVMNFSPRKLKYLSMVPPGGNWRSMPEEMQKESMGKSWYLKGGRSAYWRKLSFQFPSPTVVTMPNHAGTSMCHPTELRAISVGEAAAIQEFPDYWKFEGTTTEKFRQIGNAVPVRLGKVAGEAAMELLHRIQENKVADLVTPDYIETHIRPHIRTRSFFKNGQAYSGDVSYYDLEEEV
>NZ_CP040309.1|WP_000446132.1|604406_604979_-|Polarity-suppression-protein
MESTALQQAFDTCQNNKAAWLQRKNELAAAEQEYLRLLSGEGRNVSRLDELRNIIEVRKWQVNQAAGRYIRSHEAVQHISIRDRLNDFMQQHGTALAAALAPELMGYSELTAIARNCAIQRATDALREALLSWLAKGEKINYSAQDSDILTTIGFRPDAASVDDSREKFTPAQNMIFSRKSAQLASRQSV

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Crispr_ID: NZ_CP040309_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040309_2

799488-799619

Orphan

Consensus_repeat	Method
TTTTCAATATTGGTGAT	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP040309_2

>merge|NZ_CP040309|2|799488-799619|PILER-CR
TTTCAATATTGGTGATCCATAAAACAATATTGAAAATTTCTTTTTGCTACGCCGTGTTTTCAATATTGGTGAGGAACTTAACAATATTGAAAGTTGGATTTATCTGCGTGTGACATTTTCAATATTGGTGAT

>NZ_CP040309|2|1|799488-799619|PILER-CR
TTTCAATATTGGTGATC	CATAAAACAATATTGAAAATTTCTTTTTGCTACGCCGTGT
TTTCAATATTGGTGAGG	AACTTAACAATATTGAAAGTTGGATTTATCTGCGTGTGACAT
TTTCAATATTGGTGAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040309.1\|WP_001287748.1\|801486_802773_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|182273
NZ_CP040309.1\|WP_000597260.1\|786923_788072_+\|carbamoyl-phosphate-synthase-small-subunit	unknown	unknown	gnl\|CDD\|237139
NZ_CP040309.1\|WP_000125566.1\|807695_807929_+\|antitoxin	unknown	unknown	gnl\|CDD\|227619
NZ_CP040309.1\|WP_000600700.1\|804553_805084_+\|glutathione-regulated-potassium-efflux-system-oxidoreductase-KefF	unknown	unknown	gnl\|CDD\|234852
NZ_CP040309.1\|WP_000624372.1\|807130_807610_+\|type-3-dihydrofolate-reductase	unknown	unknown	gnl\|CDD\|182714
NZ_CP040309.1\|WP_001183179.1\|803114_804446_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340874
NZ_CP040309.1\|WP_001508854.1\|795202_796420_-\|L-carnitine-CoA-transferase	unknown	unknown	gnl\|CDD\|179589
NZ_CP040309.1\|WP_000122894.1\|792085_792676_-\|carnitine-operon-protein-CaiE	unknown	unknown	gnl\|CDD\|184189
NZ_CP040309.1\|WP_001126371.1\|788089_791311_+\|carbamoyl-phosphate-synthase-large-subunit	unknown	unknown	gnl\|CDD\|235393
NZ_CP040309.1\|WP_000347117.1\|796548_797691_-\|crotonobetainyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|179566
NZ_CP040309.1\|WP_000692204.1\|799709_800480_+\|electron-transfer-flavoprotein-FixA	unknown	unknown	gnl\|CDD\|179569
NZ_CP040309.1\|WP_001310172.1\|792681_793467_-\|crotonobetainyl-CoA-hydratase	unknown	unknown	gnl\|CDD\|179599
NZ_CP040309.1\|WP_000377184.1\|805076_806939_+\|glutathione-regulated-potassium-efflux-system-protein-KefC	unknown	unknown	gnl\|CDD\|235131
NZ_CP040309.1\|WP_000203741.1\|802769_803057_+\|ferredoxin-like-protein-FixX	unknown	unknown	gnl\|CDD\|185346
NZ_CP040309.1\|WP_000787124.1\|797721_799236_-\|L-carnitine/gamma-butyrobetaine-antiporter	unknown	unknown	gnl\|CDD\|179568
NZ_CP040309.1\|WP_001091483.1\|800494_801436_+\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	unknown	unknown	gnl\|CDD\|235120
NZ_CP040309.1\|WP_001301863.1\|793575_795129_-\|crotonobetaine/carnitine-CoA-ligase	unknown	unknown	gnl\|CDD\|181195
NZ_CP040309.1\|WP_000543582.1\|785646_786468_+\|4-hydroxy-tetrahydrodipicolinate-reductase	unknown	unknown	gnl\|CDD\|223366
NZ_CP040309.1\|WP_000333125.1\|791571_791967_+\|carnitine-metabolism-transcriptional-regulator-CaiF	unknown	unknown	gnl\|CDD\|183154
NZ_CP040309.1\|WP_001160975.1\|807931_808246_+\|plasmid-maintenance-protein-CcdB	unknown	unknown	gnl\|CDD\|376629

Protein	Function_ID	Function_description	E-value
NZ_CP040309.1\|WP_001287748.1\|801486_802773_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|182273	PRK10157, PRK10157, putative oxidoreductase FixC; Provisional.	0
NZ_CP040309.1\|WP_000597260.1\|786923_788072_+\|carbamoyl-phosphate-synthase-small-subunit	gnl\|CDD\|237139	PRK12564, PRK12564, carbamoyl-phosphate synthase small subunit.	0
NZ_CP040309.1\|WP_000125566.1\|807695_807929_+\|antitoxin	gnl\|CDD\|227619	COG5302, COG5302, Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid [General function prediction only].	2.77856e-23
NZ_CP040309.1\|WP_000600700.1\|804553_805084_+\|glutathione-regulated-potassium-efflux-system-oxidoreductase-KefF	gnl\|CDD\|234852	PRK00871, PRK00871, glutathione-regulated potassium-efflux system oxidoreductase KefF.	9.50739e-133
NZ_CP040309.1\|WP_000624372.1\|807130_807610_+\|type-3-dihydrofolate-reductase	gnl\|CDD\|182714	PRK10769, folA, type 3 dihydrofolate reductase.	1.59192e-126
NZ_CP040309.1\|WP_001183179.1\|803114_804446_+\|MFS-transporter	gnl\|CDD\|340874	cd17316, MFS_SV2_like, Metazoan Synaptic vesicle glycoprotein 2 (SV2) and related small molecule transporters of the Major Facilitator Superfamily. This family is composed of metazoan synaptic vesicle glycoprotein 2 (SV2) and related small molecule transporters including those that transport inorganic phosphate (Pht), aromatic compounds (PcaK and related proteins), proline/betaine (ProP), alpha-ketoglutarate (KgtP), citrate (CitA), shikimate (ShiA), and cis,cis-muconate (MucK), among others. SV2 is a transporter-like protein that serves as the receptor for botulinum neurotoxin A (BoNT/A), one of seven neurotoxins produced by the bacterium Clostridium botulinum. BoNT/A blocks neurotransmitter release by cleaving synaptosome-associated protein of 25 kD (SNAP-25) within presynaptic nerve terminals. Also included in this family is synaptic vesicle 2 (SV2)-related protein (SVOP) and similar proteins. SVOP is a transporter-like nucleotide binding protein that localizes to neurotransmitter-containing vesicles. The SV2-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.18052e-58
NZ_CP040309.1\|WP_001508854.1\|795202_796420_-\|L-carnitine-CoA-transferase	gnl\|CDD\|179589	PRK03525, PRK03525, L-carnitine CoA-transferase.	0
NZ_CP040309.1\|WP_000122894.1\|792085_792676_-\|carnitine-operon-protein-CaiE	gnl\|CDD\|184189	PRK13627, PRK13627, carnitine operon protein CaiE; Provisional.	2.91191e-141
NZ_CP040309.1\|WP_001126371.1\|788089_791311_+\|carbamoyl-phosphate-synthase-large-subunit	gnl\|CDD\|235393	PRK05294, carB, carbamoyl-phosphate synthase large subunit.	0
NZ_CP040309.1\|WP_000347117.1\|796548_797691_-\|crotonobetainyl-CoA-dehydrogenase	gnl\|CDD\|179566	PRK03354, PRK03354, crotonobetainyl-CoA dehydrogenase; Validated.	0
NZ_CP040309.1\|WP_000692204.1\|799709_800480_+\|electron-transfer-flavoprotein-FixA	gnl\|CDD\|179569	PRK03359, PRK03359, putative electron transfer flavoprotein FixA; Reviewed.	6.8619e-170
NZ_CP040309.1\|WP_001310172.1\|792681_793467_-\|crotonobetainyl-CoA-hydratase	gnl\|CDD\|179599	PRK03580, PRK03580, crotonobetainyl-CoA hydratase.	6.1008e-179
NZ_CP040309.1\|WP_000377184.1\|805076_806939_+\|glutathione-regulated-potassium-efflux-system-protein-KefC	gnl\|CDD\|235131	PRK03562, PRK03562, glutathione-regulated potassium-efflux system protein KefC; Provisional.	0
NZ_CP040309.1\|WP_000203741.1\|802769_803057_+\|ferredoxin-like-protein-FixX	gnl\|CDD\|185346	PRK15449, PRK15449, ferredoxin-like protein FixX; Provisional.	1.84173e-69
NZ_CP040309.1\|WP_000787124.1\|797721_799236_-\|L-carnitine/gamma-butyrobetaine-antiporter	gnl\|CDD\|179568	PRK03356, PRK03356, L-carnitine/gamma-butyrobetaine antiport BCCT transporter.	0
NZ_CP040309.1\|WP_001091483.1\|800494_801436_+\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	gnl\|CDD\|235120	PRK03363, fixB, electron transfer flavoprotein subunit alpha/FixB family protein.	0
NZ_CP040309.1\|WP_001301863.1\|793575_795129_-\|crotonobetaine/carnitine-CoA-ligase	gnl\|CDD\|181195	PRK08008, caiC, putative crotonobetaine/carnitine-CoA ligase; Validated.	0
NZ_CP040309.1\|WP_000543582.1\|785646_786468_+\|4-hydroxy-tetrahydrodipicolinate-reductase	gnl\|CDD\|223366	COG0289, DapB, Dihydrodipicolinate reductase [Amino acid transport and metabolism].	7.8312e-142
NZ_CP040309.1\|WP_000333125.1\|791571_791967_+\|carnitine-metabolism-transcriptional-regulator-CaiF	gnl\|CDD\|183154	PRK11476, PRK11476, carnitine metabolism transcriptional regulator CaiF.	1.42176e-74
NZ_CP040309.1\|WP_001160975.1\|807931_808246_+\|plasmid-maintenance-protein-CcdB	gnl\|CDD\|376629	pfam01845, CcdB, CcdB protein.	6.75893e-37

>NZ_CP040309.1|WP_000787124.1|797721_799236_-|L-carnitine/gamma-butyrobetaine-antiporter
MKNEKRKTGIEPKVFFPPLIIVGILCWLTVRDLDAANVVINAVFSYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGNEPPEFSTASWIFMMFASCTSAAVLFWGSIEIYYYISTPPFGLEPNSTGAKELGLAYSLFLWGPLPWATYSFLSVAFAYFFFVRKMEVIRPSSTLVPLVGEKHAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTECMQWLFGIPHTLQLDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIVSGASFIMNYFTDSVGMLLMYLPRMLFYTDPIAKGGFPQGWTVFYWAWWVIYAIQMSIFLARISRGRTVRELCFGMVMGLTASTWILWTVLGSNTLLLIDKNIINIPNLIEQYGVARAIIETWAALPLSTATMWGFFILCFIATVTLVNACSYTLAMSTCREVRDGEEPPLLVRIGWSILVGIIGIVLLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKDAKQNWKD
>NZ_CP040309.1|WP_000347117.1|796548_797691_-|crotonobetainyl-CoA-dehydrogenase
MDFNLNDEQELFVAGIRELMASENWEAYFAECDRDSVYPERFVKALADMGIDSLLIPEEHGGLDAGFVTLAAVWMELGRLGAPTYVLYQLPGGFNTFLREGTQEQIDKIMAFRGTGKQMWNSAITEPGAGSDVGSLKTTYTRRNGKIYLNGSKCFITSSAYTPYIVVMARDGASPDKPVYTEWFVDMSKPGIKVTKLEKLGLRMDSCCEITFDDVELDEKDMFGREGNGFNRVKEEFDHERFLVALTNYGTAMCAFEDAARYANQRVQFGEAIGRFQLIQEKFAHMAIKLNSMKNMLYEAAWKADNGTITSGDAAMCKYFCANAAFEVVDSAMQVLGGVGIAGNHRISRFWRDLRVDRVSGGSDEMQILTLGRAVLKQYR
>NZ_CP040309.1|WP_001508854.1|795202_796420_-|L-carnitine-CoA-transferase
MDHLPMPKFGPLAGLRVVFSGIEIAGPFAGQMFAEWGAEVIWIENVAWADTIRVQPNYPQLSRRNLHALSLNIFKDEGREAFLKLMETTDIFIEASKGPAFARRGITDEVLWQHNPKLVIAHLSGFGQYGTEEYTNLPAYNTIAQAFSGYLIQNGDVDQPMPAFPYTADYFSGLTATTAALAALHKARETGKGESIDIAMYEVMLRMGQYFMMDYFNGGEMCPRMSKGKDPYYAGCGLYKCADGYIVMELVGITQIEECFKDIGLAHLLGTPEIPEGTQLIHRIECPYGPLVEEKLDAWLAAHTIAEVKERFTELNIACAKVLTVPELESNPQYVARESITQWQTMDGRTCKGPNIMPKFKNNPGQIWRGMPSHGMDTAAILKNIGYSENDIQELVSKGLAKVED
>NZ_CP040309.1|WP_001301863.1|793575_795129_-|crotonobetaine/carnitine-CoA-ligase
MDIIGGQHLRQMWDDLADVYGHKTALICESSGGVVNRYSYLELNQEINRTANLFYTLGIRKGDKVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLREESAWILQNSQACLLVTSAQFYPMYQQIQQEDATQLRHICLTDVALPADDGVSSFTQLKNQQPATLCYAPPLSTDDTAEILFTSGTTSRPKGVVITHYNLRFAGYYSAWQCALRDDDVYLTVMPAFHIDCQCTAAMAAFSAGATFVLVEKYSARAFWGQVQKYRATITECIPMMIRTLMVQPPSANDRQHRLREVMFYLNLSEQEKDTFCERFGVRLLTSYGMTETIVGIIGDRPGDKRRWPSIGRAGFCYDAEIRDDHNRPLPAGEIGEICIKGVPGKTIFKEYFLNPKATAKVLEADGWLHTGDTGYRDEEGFFYFIDRRCNMIKRGGENVSCVELENIIATHPKIQDIVVVGIKDSIRDEAIKAFVVLNEGETLSEEEFFRFCEQNMAKFKVPSYLEIRKDLPRNCSGKIIRKNLK
>NZ_CP040309.1|WP_001310172.1|792681_793467_-|crotonobetainyl-CoA-hydratase
MSESLHLTRNGSILEITLDRPKANAIDAKTSFEMGEVFLNFRDDPQLRVAIITGAGEKFFSAGWDLKAAAEGEAPDADFGPGGFAGLTEIFNLDKPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKILPPAIVNEMVMTGRRMGAEEALRWGIVNRVVSQAELMDNARELAQQLVNSAPLAIAALKEIYRTTSEMPVEESYRYIRSGVLKHYPSVLHSEDAIEGPLAFAEKRDPVWKGR
>NZ_CP040309.1|WP_000122894.1|792085_792676_-|carnitine-operon-protein-CaiE
MSYYAFEGLIPVVHPTAFVHPSAVLIGDVIVGAGVYIGPLASLRGDYGRLIVQAGANIQDGCIMHGYTDTDTIVGENGHIGHGAILHGCVIGRDALVGMNSVIMDGAVIGEESIVAAMSFVKAGFHGEKRQLLMGTPARAVRSVSDDELHWKRLNTKEYQDLVGRCHASLHETQPLRQMEENRPRLQGTTDVTPKR
>NZ_CP040309.1|WP_000333125.1|791571_791967_+|carnitine-metabolism-transcriptional-regulator-CaiF
MCEGYVEKPLYLLIAEWMMAENRWVIAREISIHFDIEHSKAVNTLTYILSEVTEISCEVKMIPNKLEGRGCQCQRLVKVVDIDEQIYARLRNNSREKLVGVRKTPRIPAVPLTELNREQKWQMMLSKSMRR
>NZ_CP040309.1|WP_001126371.1|788089_791311_+|carbamoyl-phosphate-synthase-large-subunit
MPKRTDIKSILILGAGPIVIGQACEFDYSGAQACKALREEGYRVILVNSNPATIMTDPEMADATYIEPIHWEVVRKIIEKERPDAVLPTMGGQTALNCALELERQGVLEEFGVTMIGATADAIDKAEDRRRFDVAMKKIGLETARSGIAHTMEEALAVAADVGFPCIIRPSFTMGGSGGGIAYNREEFEEICARGLDLSPTKELLIDESLIGWKEYEMEVVRDKNDNCIIVCSIENFDAMGIHTGDSITVAPAQTLTDKEYQIMRNASMAVLREIGVETGGSNVQFAVNPKNGRLIVIEMNPRVSRSSALASKATGFPIAKVAAKLAVGYTLDELMNDITGGRTPASFEPSIDYVVTKIPRFNFEKFAGANDRLTTQMKSVGEVMAIGRTQQESLQKALRGLEVGATGFDPKVSLDDPEALTKIRRELKDAGAERIWYIADAFRAGLSVDGVFNLTNIDRWFLVQIEELVRLEEKVAEVGITGLNAEFLRQLKRKGFADARLAKLAGVREAEIRKLRDQYDLHPVYKRVDTCAAEFATDTAYMYSTYEEECEANPSTDREKIMVLGGGPNRIGQGIEFDYCCVHASLALREDGYETIMVNCNPETVSTDYDTSDRLYFEPVTLEDVLEIVRIEKPKGVIVQYGGQTPLKLARALEAAGVPVIGTSPDAIDRAEDRERFQHAVDRLKLKQPANATVTAIEMAVEKAKEIGYPLVVRPSYVLGGRAMEIVYDEADLRRYFQTAVSVSNDAPVLLDHFLDDAVEVDVDAICDGEMVLIGGIMEHIEQAGVHSGDSACSLPAYTLSQEIQDVMRQQVQKLAFELQVRGLMNVQFAVKNNEVYLIEVNPRAARTVPFVSKATGVPLAKVAARVMAGKSLAEQGVTKEVIPPYYSVKEVVLPFNKFPGVDPLLGPEMRSTGEVMGVGRTFAEAFAKAQLGSNSTMKKHGRALLSVREGDKERVVDLAAKLLKQGFELDATHGTAIVLGEAGINPRLVNKVHEGRPHIQDRIKNGEYTYIINTTSGRRAIEDSRVIRRSALQYKVHYDTTLNGGFATAMALNADATEKVISVQEMHAQIK
>NZ_CP040309.1|WP_000597260.1|786923_788072_+|carbamoyl-phosphate-synthase-small-subunit
MIKSALLVLEDGTQFHGRAIGATGSAVGEVVFNTSMTGYQEILTDPSYSRQIVTLTYPHIGNVGTNDADEESSQVHAQGLVIRDLPLIASNFRNTEDLSSYLKRHNIVAIADIDTRKLTRLLREKGAQNGCIIAGDNPDAALALEKARAFPGLNGMDLAKEVTTAEAYSWTQGSWTLTGGLPEAKKEDELPFHVVAYDFGAKRNILRMLVDRGCRLTIVPAQTSAEDVLKMNPDGIFLSNGPGDPAPCDYAITAIQKFLETDIPVFGICLGHQLLALASGAKTVKMKFGHHGGNHPVKDVEKNVVMITAQNHGFAVDEATLPANLRVTHKSLFDGTLQGIHRTDKPAFSFQGHPEASPGPHDAAPLFDHFIELIEQYRKTAK
>NZ_CP040309.1|WP_000543582.1|785646_786468_+|4-hydroxy-tetrahydrodipicolinate-reductase
MHDANIRVAIAGAGGRMGRQLIQAALALEGVQLGAALEREGSSLLGSDAGELAGAGKTGVTVQSSLDAIKDDFDVFIDFTRPEGTLNHLAFCRQHGKGMVIGTTGFDEAGKQAIRDAAADIAIVFAANFSVGVNVMLKLLEKAAKVMGDYTDIEIIEAHHRHKVDAPSGTALAMGEAIAHALDKDLKDCAVYSREGHTGERVPGTIGFATVRAGDIVGEHTAMFADIGERLEITHKASSRMTFANGAVRSALWLSGKENGLFDMRDVLDLNNL
>NZ_CP040309.1|WP_000692204.1|799709_800480_+|electron-transfer-flavoprotein-FixA
MKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDLNAIEAACQLKQQAAEAQVTALSVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQQTASALAAAAQKAGFDLILCGDGSSDLYAQQVGLLVGEILNIPAVNGVSKIISLTADTLTVERELEDETETLSIPLPAVVAVSTDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAEAAWSEQQVAAPKQRERQRIVIEGDGEEQIAAFAENLRKVI
>NZ_CP040309.1|WP_001091483.1|800494_801436_+|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein
MNTFSQVWVFSDTPSRLPELMNGAQALANQINAFVLNDADGAQAIQLGANHVWKLNGKPDDRMIEDYASVMADTIRQHGADGLVLLPNTRRGKLLAAKLGYRLKAAVSNDASTVSVQDGKATVKHMVYGGLAIGEERIATPYAVLTISSGTFDAAQPDASRTGETHTVEWQAPAVAITRTATQARQSNSVDLDKARLVVSVGRGIGSKENIALAEQLCKAIGAELACSRPVAENEKWMEHERYVGISNLMLKPELYLAVGISGQIQHMVGANASQTIFAINKDKNAPIFQYADYGIVGDAVKILPALTAALAR
>NZ_CP040309.1|WP_001287748.1|801486_802773_+|FAD-dependent-oxidoreductase
MSEDIFDAIIVGAGLAGSVAALVLAREGAQVLVIERGNSAGAKNVTGGRLYAHSLEHIIPGFAESAPVERLITHEKLAFMTEKSAMTMDYCNGDETSPSQRSYSVLRSKFDAWLMEQAEEAGAQLITGIRVDNLVQRDGKVVGVEADGDVIEAKTVILADGVNSILAEKLGMAKRVKPTNVAVGVKELIELPKSVIEDRFQLQGNQGAACLFAGSPTDGLMGGGFLYTNENTLSLGLVCGLHHLHDAKKSVPQMLEDFKQHPAVAPLIAGGKLVEYSAHVVPEAGINMLPELVGDGVLIAGDAAGMCMNLGFTIRGMDLAIAAGEAAAKTVLSAMKSDDFSKQKLAEYRQHLESGPLRDMRMYQKLPAFLDNPRMFSGYPELAVGVARDLFTIDGSAPELMRKKILRHGKKVGFINLIKDGMKGVTVL
>NZ_CP040309.1|WP_000203741.1|802769_803057_+|ferredoxin-like-protein-FixX
MTSPVNVDVKLGVNKFNVDEEHPHIVVKADADKQALELLVKACPAGLYKKQDDGSVRFDYAGCLECGTCRILGLGSALEQWEYPRGTFGVEFRYG
>NZ_CP040309.1|WP_001183179.1|803114_804446_+|MFS-transporter
MQPSRNFDDLKFSSIHRRILLWGSGGPFLDGYILVMIGVALEQLTPALKLDADWIGLLGAGTLAGLFVGTSLFGYISDKVGRRKMFLIDIIAIGVISVATMFVSSPVELLVMRVLIGIVIGADYPIATSMITEFSSTRQRAFSISFIAAMWYVGATCADLVGYWLYDVEGGWRWMLGSAAIPCLLILIGRFELPESPRWLLRKGRVKECEEMMIKLFGGPVAFDEEQPQQTRFRDLFNRRHFPFVLFVAAIWTCQVIPMFAIYTFGPQIVGLLGLGVGKNAALGNVVISLFFMLGCIPPMLWLNTAGRRPLLIGSFAMMTLALAVLGLIPDMGIWLVVMALAVYAFFSGGPGNLQWLYPNELFPTDIRASAVGVIMSLSRIGTIVSTWALPIFINNYGISNTMLMGAGISLFGLLISVAFAPETRGMSLAQTSNMTIRGQRMG
>NZ_CP040309.1|WP_000600700.1|804553_805084_+|glutathione-regulated-potassium-efflux-system-oxidoreductase-KefF
MILIIYAHPYPHHSHANKRMFEQARTLEGVEIRSLYQLYPDFNIDIAAEQEALSRADLIVWQHPMQWYSIPPLLKLWIDKVFSHGWAYGHGGTALHGKHLLWAVTTGGGESHFEIGAHPGFDVLSQPLQATAIYCGLNWLPPFAMHCTFICDDETLEGQARHYKQRLLEWQEAHHG
>NZ_CP040309.1|WP_000377184.1|805076_806939_+|glutathione-regulated-potassium-efflux-system-protein-KefC
MDSHTLVQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPWGLRLVTDAESILHFAEIGVVLMLFIIGLELDPQRLWKLRAAVFGGGALQMVICGGLLGLFCMLLGLRWQVAELIGMTLALSSTAIAMQAMNERNLMVTQMGRSAFAVLLFQDIAAIPLVAMIPLLAASSASTTMGAFALSALKVAGALVLVVLLGRYVTRPALRFVARSGLREVFSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLFFIGVGMSIDFGTLIENPLRIVILLLGFLIIKIAMLWLIARPLQVPNKQRRWFAVLLGQGSEFAFVVFGAAQMANVLEPEWAKSLTLAVALSMAATPILLVILNRLEQSSTEEAREADEIDEEQPRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTNLQLTEMVKEHFPHLQIIARARDVDHYICLRQAGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMAMVENDTKARAAVYKRTSAMLSEIITEDREHLSLIQRHGWQGTEEGKHTGNMADEPETKPSS
>NZ_CP040309.1|WP_000624372.1|807130_807610_+|type-3-dihydrofolate-reductase
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTRESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
>NZ_CP040309.1|WP_000125566.1|807695_807929_+|antitoxin
MTAKRTTQSVTVTVDRELVNRARDAGLNMSATLTVALNAELKKHAATRWREENAEAIAALNQLADETGCFSDEYRSF
>NZ_CP040309.1|WP_001160975.1|807931_808246_+|plasmid-maintenance-protein-CcdB
MQFTVYRSRSRNAAFPFVIDVTSDIIGVINRRIVIPLTPIERFSRIRPPERLNPILLLVDGKEYVLMTHETATVPVNALGTKFCDASAHRTLIKGALDFMLDGI

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Crispr_ID: NZ_CP040309_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040309_3

824389-824523

Orphan

Consensus_repeat	Method
TGCCGGATGCGCGTTGCTTATCCGGCCTACAAAATCGCAGCGTGTAGGCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040309_3

>merge|NZ_CP040309|3|824389-824523|CRISPRCasFinder
TGCCGGATGCGCGTTGCTTATCCGGCCTACAAAATCGCAGCGTGTAGGCCAGATAAGACGCGTCAGCGTCGCATCAGGCGCTGAATGCCGGATGCGCGTTGCTTATCCGGCCTACAAAATTGCAGCGTGTAGGCC

>NZ_CP040309|3|2|824389-824523|CRISPRCasFinder
TGCCGGATGCGCGTTGCTTATCCGGCCTACAAAATCGCAGCGTGTAGGCC	AGATAAGACGCGTCAGCGTCGCATCAGGCGCTGAA
TGCCGGATGCGCGTTGCTTATCCGGCCTACAAAATTGCAGCGTGTAGGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040309.1\|WP_000888654.1\|823679_824375_-\|L-ribulose-5-phosphate-4-epimerase	unknown	unknown	gnl\|CDD\|236181
NZ_CP040309.1\|WP_001117011.1\|818183_821090_-\|RNA-polymerase-associated-protein-RapA	unknown	unknown	gnl\|CDD\|235319
NZ_CP040309.1\|WP_000035699.1\|821253_823605_-\|DNA-polymerase-II	unknown	unknown	gnl\|CDD\|235595
NZ_CP040309.1\|WP_000800457.1\|811284_812571_-\|peptidylprolyl-isomerase-SurA	unknown	unknown	gnl\|CDD\|236758
NZ_CP040309.1\|WP_000916267.1\|829941_830640_-\|thiamine-ABC-transporter-ATP-binding-protein-ThiQ	unknown	unknown	gnl\|CDD\|182716
NZ_CP040309.1\|WP_001148407.1\|829090_829855_+\|DedA-family-protein	unknown	unknown	gnl\|CDD\|223659
NZ_CP040309.1\|WP_000746183.1\|812623_814978_-\|LPS-assembly-protein-LptD	unknown	unknown	gnl\|CDD\|235158
NZ_CP040309.1\|WP_001200573.1\|815232_816048_+\|co-chaperone-DjlA	unknown	unknown	gnl\|CDD\|236512
NZ_CP040309.1\|WP_001138626.1\|834362_836021_-\|HTH-type-transcriptional-regulator-SgrR	unknown	unknown	gnl\|CDD\|184188
NZ_CP040309.1\|WP_000151715.1\|824574_826077_-\|L-arabinose-isomerase	unknown	unknown	gnl\|CDD\|179503
NZ_CP040309.1\|WP_000235663.1\|830623_832234_-\|thiamine/thiamine-pyrophosphate-ABC-transporter-permease-ThiP	unknown	unknown	gnl\|CDD\|181853
NZ_CP040309.1\|WP_000525186.1\|817512_818172_-\|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA	unknown	unknown	gnl\|CDD\|236659
NZ_CP040309.1\|WP_001300811.1\|828126_829005_+\|arabinose-operon-transcriptional-regulator-AraC	unknown	unknown	gnl\|CDD\|236717
NZ_CP040309.1\|WP_000951872.1\|826087_827788_-\|ribulokinase	unknown	unknown	gnl\|CDD\|235221
NZ_CP040309.1\|WP_000241259.1\|810295_811285_-\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	unknown	unknown	gnl\|CDD\|234696
NZ_CP040309.1\|WP_001248768.1\|836109_836241_+\|glucose-uptake-inhibitor-SgrT	unknown	unknown	gnl\|CDD\|374203
NZ_CP040309.1\|WP_001304001.1\|816342_817095_+\|UDP-pyrophosphate-phosphatase	unknown	unknown	unknown
NZ_CP040309.1\|WP_001065380.1\|809477_810299_-\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	unknown	unknown	gnl\|CDD\|234708
NZ_CP040309.1\|WP_001301693.1\|832209_833193_-\|thiamine-ABC-transporter-substrate-binding-subunit	unknown	unknown	gnl\|CDD\|236883
NZ_CP040309.1\|WP_000868321.1\|833564_834134_+\|T3SS-effector-EspY2	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP040309.1\|WP_000888654.1\|823679_824375_-\|L-ribulose-5-phosphate-4-epimerase	gnl\|CDD\|236181	PRK08193, araD, L-ribulose-5-phosphate 4-epimerase AraD.	3.528e-179
NZ_CP040309.1\|WP_001117011.1\|818183_821090_-\|RNA-polymerase-associated-protein-RapA	gnl\|CDD\|235319	PRK04914, PRK04914, RNA polymerase-associated protein RapA.	0
NZ_CP040309.1\|WP_000035699.1\|821253_823605_-\|DNA-polymerase-II	gnl\|CDD\|235595	PRK05762, PRK05762, DNA polymerase II; Reviewed.	0
NZ_CP040309.1\|WP_000800457.1\|811284_812571_-\|peptidylprolyl-isomerase-SurA	gnl\|CDD\|236758	PRK10770, PRK10770, peptidyl-prolyl cis-trans isomerase SurA; Provisional.	0
NZ_CP040309.1\|WP_000916267.1\|829941_830640_-\|thiamine-ABC-transporter-ATP-binding-protein-ThiQ	gnl\|CDD\|182716	PRK10771, thiQ, thiamine ABC transporter ATP-binding protein ThiQ.	5.93317e-163
NZ_CP040309.1\|WP_001148407.1\|829090_829855_+\|DedA-family-protein	gnl\|CDD\|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	1.79494e-49
NZ_CP040309.1\|WP_000746183.1\|812623_814978_-\|LPS-assembly-protein-LptD	gnl\|CDD\|235158	PRK03761, PRK03761, LPS assembly outer membrane complex protein LptD; Provisional.	0
NZ_CP040309.1\|WP_001200573.1\|815232_816048_+\|co-chaperone-DjlA	gnl\|CDD\|236512	PRK09430, djlA, co-chaperone DjlA.	1.09407e-169
NZ_CP040309.1\|WP_001138626.1\|834362_836021_-\|HTH-type-transcriptional-regulator-SgrR	gnl\|CDD\|184188	PRK13626, PRK13626, HTH-type transcriptional regulator SgrR.	0
NZ_CP040309.1\|WP_000151715.1\|824574_826077_-\|L-arabinose-isomerase	gnl\|CDD\|179503	PRK02929, PRK02929, L-arabinose isomerase; Provisional.	0
NZ_CP040309.1\|WP_000235663.1\|830623_832234_-\|thiamine/thiamine-pyrophosphate-ABC-transporter-permease-ThiP	gnl\|CDD\|181853	PRK09433, thiP, thiamine transporter membrane protein; Reviewed.	0
NZ_CP040309.1\|WP_000525186.1\|817512_818172_-\|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA	gnl\|CDD\|236659	PRK10158, PRK10158, bifunctional tRNA pseudouridine(32) synthase/23S rRNA pseudouridine(746) synthase RluA.	5.25024e-158
NZ_CP040309.1\|WP_001300811.1\|828126_829005_+\|arabinose-operon-transcriptional-regulator-AraC	gnl\|CDD\|236717	PRK10572, PRK10572, arabinose operon transcriptional regulator AraC.	0
NZ_CP040309.1\|WP_000951872.1\|826087_827788_-\|ribulokinase	gnl\|CDD\|235221	PRK04123, PRK04123, ribulokinase; Provisional.	0
NZ_CP040309.1\|WP_000241259.1\|810295_811285_-\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	gnl\|CDD\|234696	PRK00232, pdxA, 4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed.	0
NZ_CP040309.1\|WP_001248768.1\|836109_836241_+\|glucose-uptake-inhibitor-SgrT	gnl\|CDD\|374203	pfam15894, SgrT, Inhibitor of glucose uptake transporter SgrT.	0.00111324
NZ_CP040309.1\|WP_001065380.1\|809477_810299_-\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	gnl\|CDD\|234708	PRK00274, ksgA, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA.	2.27697e-148
NZ_CP040309.1\|WP_001301693.1\|832209_833193_-\|thiamine-ABC-transporter-substrate-binding-subunit	gnl\|CDD\|236883	PRK11205, tbpA, thiamine transporter substrate binding subunit; Provisional.	0

>NZ_CP040309.1|WP_000888654.1|823679_824375_-|L-ribulose-5-phosphate-4-epimerase
MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDRERGVFVIKPSGVDYSIMTADDMVVVSIETGEVVEGAKKPSSDTPTHRLLYQAFPSIGGIVHTHSRHATIWAQAGQSIPATGTTHADYFYGTIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDAAQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEVAYMGIFCRQLAPQLPDMQQTLLDKHYLRKHGAKAYYGQ
>NZ_CP040309.1|WP_000035699.1|821253_823605_-|DNA-polymerase-II
MAQAGFILTRHWRDTPQGTEVSFWLATDNGPLQVTLAPQESVAFIPADQVPRAQHILRGEQGFRLTPLALKDFHRQPVYGLYCRAHRQLMNYEKRLREGGVTVYEADVRPPERYLMERFITSPVWVEGDMHNGAIVNARLKPHPDYRPPLKWVSIDIETTRHGELYCIGLEGCGQRIVYMLGPENGDASALDFELEYVASRPQLLEKLNAWFANYDPDVIIGWNVVQFDLRMLQKHAERYRIPLRLGRDNSELEWREHGFKNGVFFAQAKGRLIIDGIEALKSAFWNFSSFSLETVAQELLGEGKSIDNPWDRMDEIDRRFAEDKPALATYNLKDCELVTQIFHKTEIMPFLLERATVNGLPVDRHGGSVAAFGHLYFPRMHRAGYVAPNLGEVPPHASPGGYVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLVEGMAQPDPEHSTEGFLDAWFSREKHCLPEIVTNIWHGRDEAKRQGNKPLSQALKIIMNAFYGVLGTTACRFFDPRLVSSITMRGHQIMRQTKALIEAQGYDVIYGDTDSTFVWLKGAHSEEEATKIGRALVQHVNVWWAETLQKQQLTSALELEYETHFCRFLMPTIRGADTGSKKRYAGLIQEGDKQRMVFKGLETVRTDWTPLAQQFQQELYLRIFRNEPYQEYFRETIDKLMAGELDARLVYRKRLRRPLSEYQRNVPPHVRAARLADEENQKRGRPLQYQNRGTIKYVWTTNGPEPLDYQRSPLDYEHYLTRQLQPVAEGILPFIEDNFATLMTGQLGLF
>NZ_CP040309.1|WP_001117011.1|818183_821090_-|RNA-polymerase-associated-protein-RapA
MPFTLGQRWISDTESELGLGTVVAVDARTVTLLFPSTGENRLYARSDSPVTRVMFNPGDTITSHDGWQMQVEEVKEENGLLTYIGTRLDTEESGVALREVFLDSKLVFSKPQDRLFAGQIDRMDRFALRYRARKYSSEQFRMPYSGLRGQRTSLIPHQLNIAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIIVPETLQHQWLVEMLRRFNLRFALFDDERYAEAQHDAYNPFDTEQLVICSLDFARRSKQRLEHLCEAEWDLLVVDEAHHLVWSEDAPSREYQAIEQLAEHVPGVLLLTATPEQLGMESHFARLRLLDPNRFHDFAQFVEEQKNYRPVADAVAMLLAGNKLSNDELNMLGEMIGEQDIEPLLQAANSDSEDAQSARQELVSMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIKLPLPTQYQTAIKVSGIMGARKSAEDRARDMLYPERIYQEFEGDNATWWNFDPRVEWLMGYLTSHRSQKVLVICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIGSEGRNFQFASHMVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRWYHEGLDAFEHTCPTGRTIYDSVYNDLINYLASPDQTEGFDDLIKNCREQHEALKAQLEQGRDRLLEIHSNGGEKAQALAESIEEQDDDTNLIAFAMNLFDIIGINQDDRGDNMIVLTPSDHMLVPDFPGLSEDGITITFDREVALAREDAQFITWEHPLIRNGLDLILSGDTGSSTISLLKNKALPVGTLLVELIYVVEAQAPKQLQLNRFLPPTPVRMLLDKNGNNLAAQVEFETFNRQLNAVNRHTGSKLVNAVQQDVHAILQLGEAQIEKSARALIDAARNEADEKLSAELSRLEALRAVNPNIRDDELTAIESNRQQVMESLDQAGWRLDALRLIVVTHQ
>NZ_CP040309.1|WP_000525186.1|817512_818172_-|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA
MGMENYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDYPQAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPADF
>NZ_CP040309.1|WP_001304001.1|816342_817095_+|UDP-pyrophosphate-phosphatase
MKVSVPGMPATLLNMSNNDIYKMVSGDKMDMKMNIFQRLWETLRHLFWSDKQTEAYKLLFNFVNKKAGNINASKYFTGAVNENEKEKFIHSLELFNELKTCAKNPDEMVAKGNMSWVAQTFGDIELSVTFFIENKEICTQTLQLHKGPGNLGVDLREAYLPGVDMRDCYLGLKTMKGHNKVLYLEPGWNANLDGATLDGATLDGATVDGATHLYDEVIIINKITPKKIDTEEVATKQSTAEQITDNAIIE
>NZ_CP040309.1|WP_001200573.1|815232_816048_+|co-chaperone-DjlA
MQYWGKIIGVAVALLMGGGFWGVVLGLLIGHMFDKARSRKMAWFANQRERQALFFATTFEVMGHLTKSKGRVTEADIHIASQLMDRMNLHGASRTAAQNAFRVGKSDNYPLREKMRQFRSVCFGRFDLIRMFLEIQIQAAFADGSLHPNERAVLYVIAEELGISRAQFDQFLRMMQGGAQFGGGYQQQSGGGNWQQAQRGPTLEDACNVLGVKPTDDATTIKRAYRKLMSEHHPDKLVAKGLPPEMMEMAKQKAQEIQQAYELIKQQKGFK
>NZ_CP040309.1|WP_000746183.1|812623_814978_-|LPS-assembly-protein-LptD
MKKRIPTLLATMIATALYSQQGLAADLASQCMLGVPSYDRPLVQGDTNDLPVTINANHAKGDYPDDAVFTGSVDIMQGNSRLQADEVQLHQKEAPGQPEPVRTVDALGNVHYDDNQVILKGPKGWANLNTKDTNVWEGDYQMVGRQGRGKADLMKQRGENRYTILDNGSFTSCLPGSDTWSVVGSEIIHDREEQVAEIWNARFKVGPVSIFYSPYLQLPVGDKRRSGFLIPNAKYTTTNYFEFYLPYYWNIAPNMDATITPHYMHRRGNIMWENEFRYLSQAGAGLMELDYLPSDKVYEDEHPNDDSSRRWLFYWNHSGVMDQVWRFNVDYTKVSDPSYFNDFDNKYGSSTDGYATQKFSVGYAVQNFNATVSTKQFQVFSEQNTSSYSAEPQLDVNYYQNDVGPFDTRIYGQAVHFVNTRDDMPEATRVHLEPTINLPLSNNWGSINTEAKLLATHYQQTNLDWYNSRNTTKLDESVNRVMPQFKVDGKMVFERDMEMLAPGYTQTLEPRAQYLYVPYRDQSDIYNYDSSLLQSDYSGLFRDRTYGGLDRIASANQVTTGVTSRIYDDAAVERFNISVGQIYYFTESRTGDDNITWENDDKTGSLVWAGDTYWRISERWGLRGGIQYDTRLDNVATSNSSIEYRRDEDRLVQLNYRYASPEYIQATLPKYYSTAEQYKNGISQVGAVASWPIADRWSIVGAYYYDTNANKQADSMLGVQYSSCCYAIRVGYERKLNGWDNDKQHAVYDNAIGFNIELRGLSSNYGLGTQEMLRSNILPYQNTL
>NZ_CP040309.1|WP_000800457.1|811284_812571_-|peptidylprolyl-isomerase-SurA
MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDGLMQSVKLNAAQARQQLPDDATLRHQIMERLIMDQIILQMGQKMGVKISDEQLDQAIANIAKQNNMTLDQMRSRLAYDGLNYNTYRNQIRKEMIISEVRNNEVRRRITILPQEVESLAQQVGNQNDASTELNLSHILIPLPENPTSDQVNEAESQARAIVDQARNGADFGKLAIAHSADQQALNGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGESKNISVTEVHARHILLKPSPIMTDEQARVKLEQIAADIKSGKTTFAAAAKEFSQDPGSANQGGDLGWATPDIFDPAFRDALTRLNKGQMSAPVHSSFGWHLIELLDTRNVDKTDAAQKDRAYRMLMNRKFSEEAASWMQEQRASAYVKILSN
>NZ_CP040309.1|WP_000241259.1|810295_811285_-|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA
MVKTQRVVITPGEPAGIGPDLVVQLAQREWPVELVVCADATLLTDRAAMLGLPLTLRPYSPNSPAQPQTTGTLTLLPVALRESVTAGQLAIENGHYVVETLARACDGCLNGEFAALITGPVHKGVINDAGIPFTGHTEFFEERSQAKKVVMMLATEELRVALATTHLPLRDIADAITPALLHEVIAILHHDLRTKFGIAEPRILVCGLNPHAGEGGHMGTEEIDTIIPVLDELRAQGMKLNGPLPADTLFQPKYLDNADAVLAMYHDQGLPVLKYQGFGRGVNITLGLPFIRTSVDHGTALELAGRGEADVGSFITALNLAIKMIVNTQ
>NZ_CP040309.1|WP_001065380.1|809477_810299_-|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA
MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEIGPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTFNFGELAEKMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRLSVMAQYYCNVIPVLEVPPSAFTPPPKVDSAVVRLVPHATMPHPVKDVRVLSRITTEAFNQRRKTIRNSLGNLFSVEVLTGMGIDPAMRAENISVAQYCQMANYLAENAPFQES
>NZ_CP040309.1|WP_000151715.1|824574_826077_-|L-arabinose-isomerase
MTIFDNYEVWFVIGSQHLYGPETLRQVTQHAEHVVKALNTEAKLPCKLVLKPLGTTPDEITAICRDANYDDRCAGLVVWLHTFSPAKMWINGLTMLNKPLLQFHTQFNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKQAHERIGSWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVVNSISDGDVNALVDEYESCYTMTPATQIHGEKRQNVLEAARIELGMKRFLEQGGFHAFTTTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMEDYTYHFEKGNDLVLGSHMLEVCPSIAAEEKPILDVQHLGIGGKDDPARLIFNTQTGPAIVASLIDLGDRYRLLVNCIDTVKTPHSLPKLPVANALWKAQPDLPTASEAWILAGGAHHTVFSHALNLNDMRQFAEMHDIEITVIDNDTRLPAFKDALRWNEVYYGFRR
>NZ_CP040309.1|WP_000951872.1|826087_827788_-|ribulokinase
MAIAIGLDFGSDSVRALAVDCTTGEEIATSVEWYPRWQKGQFCDAPNNQFRHHPRDYIESMEAALKTVLAELSVEQRAAVVGIGVDSTGSTPAPIDADGNVLALRPEFAENPNAMFVLWKDHTAVEEAEEITRLCHAPGNVDYSRYIGGIYSSEWFWAKILHVTRQDSAVAQSAASWIELCDWVPALLSGTTRPQDIRRGRCSAGHKSLWHESWGGLPPASFFDELDPILNRHLPSPLFTDTWTADIPVGTLCPEWAQRLGLPESVVISGGAFDCHMGAVGAGAQPNALVKVIGTSTCDILIADKQSVGERAVKGICGQVDGSVVPGFIGLEAGQSAFGDIYAWFGRVLGWPLEQLAAQHPELKEQIDASQKQLLPALTEAWAKNPSLDHLPVVLDWFNGRRTPNANQRLKGVITDLNLATDAPLLFGGLIAATAFGARAIMECFTDQGIAVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAKVHADIPSAQQKMASAVEKTLQPRSEQAQRFEQLYRRYQQWAMSAEQHYLPTSAPAQAAQAVPTL
>NZ_CP040309.1|WP_001300811.1|828126_829005_+|arabinose-operon-transcriptional-regulator-AraC
MAEAQNDPLLPGYSFNAHLVAGLTPIEANGYLDFFIDRPLGMKGYILNLTIRGQGVVKNQGREFVCRPGDILLFPPGEIHHYGRHPEAREWYHQWVYFRPRAYWHEWLNWPSIFANTGFFRPDEAHQPHFSDLFGQIINAGQGEGRYSELLAINLLEQLLLRRMEAINESLHPPMDNRVREACQYISDHLADSNFDIASVAQHVCLSPSRLSHLFRQQLGISVLSWREDQRISQAKLLLSTTRMPIATVGRNVGFDDQLYFSRVFKKCTGASPSEFRAGCEEKVNDVAVKLS
>NZ_CP040309.1|WP_001148407.1|829090_829855_+|DedA-family-protein
MQALLEHFITQSTVYSLMAVVLVAFLESLALVGLILPGTVLMAGLGALIGSGELSFWHAWLAGIVGCLLGDWISFWLGWRFKKPLHRWSFLKKNKALLDKTEHALHQHSMFTILVGRFVGPTRPLVPMVAGMLDLPVAKFITPNIIGCLLWPPFYFLPGILAGAAIDIPAGMQSGEFKWLLLATAVFLWVGGWLCWRLWRSGKATDRLSHYLSRGRLLWLTPLISAIGVVALVVLVRHPLMPVYIDILRKVVGV
>NZ_CP040309.1|WP_000916267.1|829941_830640_-|thiamine-ABC-transporter-ATP-binding-protein-ThiQ
MLKLTDITWLYHHLPMRFSLTVERGEQVAILGPSGAGKSTLLNLIAGFLTPASGALTIDGVDHTTTPPSRRPVSMLFQENNLFSHLTVAQNIGLGLNPGLKLNAVQQEKMHAIARQMGIDNLMARLPGELSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEMLTLVSTSCQQQKMTLLMVSHSVEDAARIATRSVVVADGRIAWQGMTNELLSGKASASALLGITG
>NZ_CP040309.1|WP_000235663.1|830623_832234_-|thiamine/thiamine-pyrophosphate-ABC-transporter-permease-ThiP
MATRRQPLIPGWLIPGVSAATLVVAVALAAFLALWWNAPQGDWSAVWQDSYLWHVVRFSFWQAFLSALLSVVPAIFLARALYRRRFPGRLALLRLCAMTLILPVLVAVFGILSVYGRQGWLASLCQSLGLEWTFSPYGLQGILLAHVFFNLPMASRLLLQALENIPGEQRQLAAQLGMRGWHFFRFVEWPWLRRQIPPVTALIFMLCFASFATVLSLGGGPQATTIELAIYQALSYDYDPARAAMLALIQMVCCLGLVLLSQRLSKAIAPGTTLLQGWRDPDDRLHSRICDTMLIVLALLLLLPPLLAVIVDGVNRQLPEVLAQPVLWQALWTSLRIALAAGVLCVVLTMMLLWSSRELRARQKMLAGQALEMSGMLILAMPGIVLATGFFLLLNNTIGLPQSADGIVIFTNALMAIPYALKVLENPMRDITARYSMLCQSLGIEGWSRLKVVELRALKRPLAQALAFACVLSIGDFGVVALFGNDDFRTLPFYLYQQIGSYRSQDGAVTALILLLLCFLLFSVIEKIPGRNVKTD
>NZ_CP040309.1|WP_001301693.1|832209_833193_-|thiamine-ABC-transporter-substrate-binding-subunit
MLKKCLPLLLLCTAPVFAKPVLTVYTYDSFAADWGPGPVVKKAFEADCNCELKLVALEDGVSLLNRLRMEGKNSKADVVLGLDNNLLDAASKTGLFAKSGVAADAVNVPGGWNNDIFVPFDYGYFAFVYDKNKLKNPPQSLKELVESDQNWRVIYQDPRTSTPGLGLLLWMQKVYGDDAPQAWQKLAKKTVTVTKGWSEAYGLFLKGESDLVLSYTTSPAYHILEEKKDNYAAANFSEGHYLQVEVAARTAASKQPELAQKFLQFMVSPAFQNAIPTGNWMYPVANVTLPAGFEKLTKPATTLEFTPAEVAAQRQAWISEWQRAVSR
>NZ_CP040309.1|WP_000868321.1|833564_834134_+|T3SS-effector-EspY2
MKVRNPEQISIPASNTTKDPGLTNSQIIRMANLVKKTENMNIFEELWETLRNLFQSDKHSQTAARQILKDAFYFQNSDDYSKYFTGAVDGKARDKLTHWLIKFNELKEYAKDPENMAAKASLSPEGTLCVSFFIGDEAIFTLELQLKKSTRTGGIDLSNAYFNGVVICGIDCLEVDLSNAETNNSRWYD
>NZ_CP040309.1|WP_001138626.1|834362_836021_-|HTH-type-transcriptional-regulator-SgrR
MPSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLLNTMQDRGWLTWEAEVGRGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKATVRQMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEENGELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIADIVSPTPWTLDIHLTQPDRWLPLLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRNSTNQLKIQAFDDFFGYRALIDEVNVWVLPEIADEPAGGLMLKGPQGEEKEIESRLEEGCYYLLFDSRTHRGANQQVRDWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHARTITSEKPAGLESLTLTFYQDHSEHRVIAGIMQQILASHQVTLEIKEISYDQWHEGEIESDIWLNSANFTLPLDFSLFAHLCEVPLLQHCIPIDWQVDAARWRNGEMNLANWCQQLVASKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDPE
>NZ_CP040309.1|WP_001248768.1|836109_836241_+|glucose-uptake-inhibitor-SgrT
MRQFYQHYFTATAKLCWLRWLSVPQRLTMLEELMQWEGSHSDY

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Crispr_ID: NZ_CP040309_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040309_4

3615882-3615993

Orphan

Consensus_repeat	Method
TTTTCTTACCTGATTCGGGTAA	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP040309_4

>merge|NZ_CP040309|4|3615882-3615993|PILER-CR
TTACCTGATTCGGGTAAGTGCCTTTACCTGATTTGGGTAAACTTTTCTTACCTGATTCAGGTAAATTTACCTCTTTCAGGTAAACTTTATTTTTCTTACCTGATTCGGGTAA

>NZ_CP040309|4|2|3615882-3615993|PILER-CR
TTACCTGATTCGGGTAAGTGCC	TTTACCTGATTTGGGTAAACTTTTC
TTACCTGATTCAGGTAAATTTA	CCTCTTTCAGGTAAACTTTATTTTTC
TTACCTGATTCGGGTAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040309.1\|WP_000971055.1\|3612092_3612233_-\|YlcG-family-protein	unknown	unknown	unknown
NZ_CP040309.1\|WP_001481254.1\|3614010_3614208_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040309.1\|WP_023148105.1\|3620243_3620534_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236900
NZ_CP040309.1\|WP_000100847.1\|3620911_3621697_+\|phage-recombination-protein-Bet	unknown	unknown	gnl\|CDD\|273871
NZ_CP040309.1\|WP_000995395.1\|3620609_3620906_+\|host-nuclease-inhibitor-protein-Gam	unknown	unknown	gnl\|CDD\|368728
NZ_CP040309.1\|WP_000186740.1\|3621693_3622371_+\|YqaJ-viral-recombinase-family-protein	unknown	unknown	gnl\|CDD\|378216
NZ_CP040309.1\|WP_001182876.1\|3616430_3616970_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368819
NZ_CP040309.1\|WP_000712399.1\|3617333_3618026_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225484
NZ_CP040309.1\|WP_000145928.1\|3614435_3614720_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040309.1\|WP_072141214.1\|3613493_3613595_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040309.1\|WP_000224907.1\|3612871_3613042_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182029
NZ_CP040309.1\|WP_001053021.1\|3613041_3613497_-\|DNA-base-flipping-protein-YbcN	unknown	unknown	gnl\|CDD\|182057
NZ_CP040309.1\|WP_000774504.1\|3612588_3612879_-\|DUF1364-domain-containing-protein	unknown	unknown	gnl\|CDD\|377777
NZ_CP040309.1\|WP_001099712.1\|3612229_3612592_-\|crossover-junction-endodeoxyribonuclease-RusA	unknown	unknown	gnl\|CDD\|182075
NZ_CP040309.1\|WP_000548547.1\|3622525_3622717_+\|DUF1382-family-protein	unknown	unknown	gnl\|CDD\|369224
NZ_CP040309.1\|WP_032195523.1\|3622370_3622553_+\|DUF1317-domain-containing-protein	unknown	unknown	gnl\|CDD\|284449
NZ_CP040309.1\|WP_000390541.1\|3613685_3613967_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040309.1\|WP_000788906.1\|3614716_3615418_-\|Replication-protein-14	unknown	unknown	gnl\|CDD\|369163
NZ_CP040309.1\|WP_001362421.1\|3618132_3619740_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238697
NZ_CP040309.1\|WP_001444000.1\|3622727_3623009_+\|cell-division-protein-ZapA	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP040309.1\|WP_032195523.1\|3622370_3622553_+\|DUF1317-domain-containing-protein	gnl\|CDD\|284449	pfam07026, DUF1317, Protein of unknown function (DUF1317). This family consists of several hypothetical bacterial and phage proteins of around 60 residues in length. The function of this family is unknown.	1.06441e-33
NZ_CP040309.1\|WP_023148105.1\|3620243_3620534_+\|hypothetical-protein	gnl\|CDD\|236900	PRK11354, kil, FtsZ inhibitor protein; Reviewed.	1.93326e-13
NZ_CP040309.1\|WP_000100847.1\|3620911_3621697_+\|phage-recombination-protein-Bet	gnl\|CDD\|273871	TIGR01913, Uncharacterized_protein_UU154, phage recombination protein Bet. This model represents the phage recombination protein Bet from a number of phage, including phage lambda. All members of this family are found in phage genomes or in putative prophage regions of bacterial genomes. [Mobile and extrachromosomal element functions, Prophage functions].	1.45393e-64
NZ_CP040309.1\|WP_001182876.1\|3616430_3616970_-\|hypothetical-protein	gnl\|CDD\|368819	pfam06254, YdaT_toxin, Putative bacterial toxin ydaT. YdaT_toxin is a family of putative bacterial toxins that are neutralized by the putative antitoxin YdaS, UniProtKB:P76063, family pfam144549.	3.00893e-37
NZ_CP040309.1\|WP_000186740.1\|3621693_3622371_+\|YqaJ-viral-recombinase-family-protein	gnl\|CDD\|378216	pfam09588, YqaJ, YqaJ-like viral recombinase domain. This protein family is found in many different bacterial species but is of viral origin. The protein forms an oligomer and functions as a processive alkaline exonuclease that digests linear double-stranded DNA in a Mg(2+)-dependent reaction, It has a preference for 5'-phosphorylated DNA ends. It thus forms part of the two-component SynExo viral recombinase functional unit.	1.4465e-29
NZ_CP040309.1\|WP_000995395.1\|3620609_3620906_+\|host-nuclease-inhibitor-protein-Gam	gnl\|CDD\|368728	pfam06064, Gam, Host-nuclease inhibitor protein Gam. The Gam protein inhibits RecBCD nuclease and is found in both bacteria and bacteriophage.	1.84559e-52
NZ_CP040309.1\|WP_000712399.1\|3617333_3618026_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|225484	COG2932, COG2932, Predicted transcriptional regulator [Transcription].	2.74867e-27
NZ_CP040309.1\|WP_000548547.1\|3622525_3622717_+\|DUF1382-family-protein	gnl\|CDD\|369224	pfam07131, DUF1382, Protein of unknown function (DUF1382). This family consists of several hypothetical Escherichia coli and bacteriophage lambda-like proteins of around 60 residues in length. The function of this family is unknown. Structural modelling suggests this domain may bind nucleic acids.	1.38504e-21
NZ_CP040309.1\|WP_000224907.1\|3612871_3613042_-\|hypothetical-protein	gnl\|CDD\|182029	PRK09689, PRK09689, prophage protein NinE; Provisional.	4.47204e-27
NZ_CP040309.1\|WP_001053021.1\|3613041_3613497_-\|DNA-base-flipping-protein-YbcN	gnl\|CDD\|182057	PRK09741, PRK09741, hypothetical protein; Provisional.	1.28739e-94
NZ_CP040309.1\|WP_000774504.1\|3612588_3612879_-\|DUF1364-domain-containing-protein	gnl\|CDD\|377777	pfam07102, DUF1364, Protein of unknown function (DUF1364). This family consists of several bacterial and phage proteins of around 95 residues in length. The function of this family is unknown.	5.39804e-47
NZ_CP040309.1\|WP_001099712.1\|3612229_3612592_-\|crossover-junction-endodeoxyribonuclease-RusA	gnl\|CDD\|182075	PRK09786, PRK09786, endodeoxyribonuclease RUS; Reviewed.	1.39408e-70
NZ_CP040309.1\|WP_000788906.1\|3614716_3615418_-\|Replication-protein-14	gnl\|CDD\|369163	pfam06992, Phage_lambda_P, Replication protein P. This family consists of several Bacteriophage lambda replication protein P like proteins. The bacteriophage lambda P protein promoters replication of the phage chromosome by recruiting a key component of the cellular replication machinery to the viral origin. Specifically, P protein delivers one or more molecules of Escherichia coli DnaB helicase to a nucleoprotein structure formed by the lambda O initiator at the lambda replication origin.	4.0258e-82
NZ_CP040309.1\|WP_001362421.1\|3618132_3619740_+\|hypothetical-protein	gnl\|CDD\|238697	cd01406, SIR2-like, Sir2-like: Prokaryotic group of uncharacterized Sir2-like proteins which lack certain key catalytic residues and conserved zinc binding cysteines; and are members of the SIR2 superfamily of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation.	5.66651e-43

>NZ_CP040309.1|WP_000788906.1|3614716_3615418_-|Replication-protein-14
MKNIAAQMVNFDREQMRRIANNMPEQYDEKPQVQQVAQIINGVFSQLLATFPASLANRDQNEVNEIRRQWVLAFRENGITSMEQVNAGMRVARRQNRPFLPSPGQFVAWCREEASVIAGLPNVSELVDMVYEYCRKRGLYPDAESYPWKSNAHYWLVTNLYQNMRANALTDAELRRKAADELTCMTARINRGEAIPEPVKQLPVMGGRPLNRVQALAKIAEIKAKFGLKGASV
>NZ_CP040309.1|WP_000145928.1|3614435_3614720_-|hypothetical-protein
MTGKEAIIHYLGTHNSFCAPDVAALTGATVTSINQAAAKMARAGLLVIEGKVWRTVYYRFATKEEREGKVSTNMIFKECRQSAAMKRVLLVYRT
>NZ_CP040309.1|WP_001481254.1|3614010_3614208_-|hypothetical-protein
MSGCSVEVVNVNTTKEPVNVFYSRKDCEESMKNIMLNHALYHEVSGREPYMAKCEQVFVSKSLMK
>NZ_CP040309.1|WP_000390541.1|3613685_3613967_-|hypothetical-protein
MEDYLVFGLGYEGDIKNDEAGLDKISVVTKSVVRSTNSNEPVVYQVTEFKEFNVVRHQAFDSEYYNIAFDVLPSRVRIDAAIRKYHPKKSSSA
>NZ_CP040309.1|WP_072141214.1|3613493_3613595_-|hypothetical-protein
MRTYNPNSLLPSLMQKCTCGSLHPTFDLCGGEA
>NZ_CP040309.1|WP_001053021.1|3613041_3613497_-|DNA-base-flipping-protein-YbcN
MNLPQDGIKLHRGNFTAIGQQIQPYLENGKCFRMVLKPWREKRSLSQNALSHMWYSEISEYLISRGKSFATSAWVKDALKHTYLGYETKDLVDVVTGEITTIQSLRHTSDLGTGEMYVFLCKVEAWAMNIGCHLTIPQSCEFQLLRDKQEA
>NZ_CP040309.1|WP_000224907.1|3612871_3613042_-|hypothetical-protein
MATPLIRVMNGHIYKVPNRRKRKPELKPSEIPTLLGYTASLVDKKWLRLAARRNHG
>NZ_CP040309.1|WP_000774504.1|3612588_3612879_-|DUF1364-domain-containing-protein
MADLRKAARSRECQVRIPGVCNGNPETSVLAHIRLTGLCGTGTKPPDLIATIACSACHDEIDRRTHFVDAAYAKECALEGMARTQVIWLKEGVIKA
>NZ_CP040309.1|WP_001099712.1|3612229_3612592_-|crossover-junction-endodeoxyribonuclease-RusA
MNTYSITLPWPPSNNRYYRHNRGRTHVSAEGQAYRDNVARIIKNAMLDIGLAMPVKIRIECHMPDRRRRDLDNLQKAAFDALTKAGFWLDDAQVVDYRVVKMPVTKGGRLELTITEMGNE
>NZ_CP040309.1|WP_000971055.1|3612092_3612233_-|YlcG-family-protein
MMFEFNMAELLRHRWGRLRLYRFPGSVLTDYRILKNYAKTLTGAGV
>NZ_CP040309.1|WP_001182876.1|3616430_3616970_-|hypothetical-protein
MQPLTYQQTSGFSPTAVINRSQIKQVPGHEKIRDAVRAWSAVDNQDVVATLIVNEYREQGGGTIDFPDDVSRTRQKLFRFLDNKFDSEKYRNNVRELTPAILAVLPLEYRGYLVEQDSFMARLAEMEKELSEAKQAVILNAPRHQKLKEISEGIVSMFRVDPELAGPLMAMVTTMLGAI
>NZ_CP040309.1|WP_000712399.1|3617333_3618026_+|helix-turn-helix-transcriptional-regulator
MKKETLADRLNLAMEQSGMSQGALAKASGVAQPTIWRLTSGNARGSTKIVEIANALGVRTEWLSSGIGPMRNDGQQSGKPAVNHSKYFKIDVLDIEVSAGPGVINREFVEVLRSVEYSFDDARHMFDGRKAENIRIINVRGDSMSGTIEPGDLLFVDITVKSFDGDGIYAFLYDDTAHVKRLQMMKDKLLVISDNKSYSPWDPIEKDEMNRVFIFGKVIGSMPQTYRKHG
>NZ_CP040309.1|WP_001362421.1|3618132_3619740_+|hypothetical-protein
MDMSKKNFEFKNYPIVFIGSGISKRYLENYPTWEELLNEYWKITNPTNDFYSYLLTIKESHKNNSDNDIDHKIYTEAASKIENDYNLLFRTGKLKLNGLDAKRVFSEDISPFKYAICQRFSNNTIRKDVNLDELASFKTLIKKAKIIITTNYDAFIENLLQEQNVTPKLYIGNNGFFEDTIGWSELYKIHGDIKDPHSIIINKDDYEKYDNKSILISAKILSNMIKNPIVFLGYSLTDRNVKKLLSDFSSQLPREDGRKSAERIILIEYKENEQEVVPKQITDQQLQITYTSVKTDNYKQIYDEISAVDEGLSPYDVLRYQRAIKTLIINEGEKGHLDTLLVSPSDLDRLEESVKQGKNLVVALGDKKYVFTQVKEINYLEDYLFNKNEISNKLAIDFILGSVNSLQLPFSKTITSCNLKELSLPAKYVLKLNQRIERHGKLDDLLNKITLDKINANKIYTNIKDIKDATFKKYKELSIVIKNIKNIPKEEIEDYVKKEAFVQFKACDVDNLKTQYRKLFLAYDLLIHGNVEKIN
>NZ_CP040309.1|WP_023148105.1|3620243_3620534_+|hypothetical-protein
MTTGGHPPPEYAQKSLYVQQPSLRAGVFMVHQHYGTQTVNRGAVMPGMLVKHKDGTWTASANLRGRLYLHRGIERTYTRDLLVEVFLDGRGNGLNR
>NZ_CP040309.1|WP_000995395.1|3620609_3620906_+|host-nuclease-inhibitor-protein-Gam
MNAYYIQDCLEAQSWARYYQQIAREEKEAELADDMEKGLPQHLFESLCIDHLQRHGASKKAITRAFDDDVEFQERMAEHIRYMVETIAHHQVDIDSEV
>NZ_CP040309.1|WP_000100847.1|3620911_3621697_+|phage-recombination-protein-Bet
MSTALATLAGKLAERVGMDSVDPQELITTLRQTAFKGDASDAQFIALLIVANQYGLNPWTKEIYAFPDKQNGIVPVVGVDGWSRIINENQQFDGMDFEQDNESCTCRIYRKDRNHPICVTEWMDECRREPFKTREGREITGPWQSHPKRMLRHKAMIQCARLAFGFAGIYDKDEAERIVENTAYTAERQPERDITPVNDETMQEINTLLIALDKTWDDDLLPLCSQIFRRDIRASSELTQAEAVKALGFLKQKATEQKVAA
>NZ_CP040309.1|WP_000186740.1|3621693_3622371_+|YqaJ-viral-recombinase-family-protein
MTPDIILQRTGIDVRAVEQGDDAWHKLRLGVITASEIHNVIAKPRSGKKWPDMKMSYFHTLLAEVCTGVAPEVNAKALAWGKQYENDARTLFEFTSGVNVTESPIIYRDESMRTACSPDGLCSDGNGLELKCPFTSRDFMKFRLGGFEAIKSAYMAQVQYSMWVTRKDAWYFANYDPRMKREGLHYVVIERNEKYMASFDEMVPEFIEKMDEALAEIGFVYGEQW
>NZ_CP040309.1|WP_032195523.1|3622370_3622553_+|DUF1317-domain-containing-protein
MKHPHDNIRVGTITFAYSVTKRGWVFPGLSVIRNPLKAQRLAEEINNKRGAVCTKHLLLN
>NZ_CP040309.1|WP_000548547.1|3622525_3622717_+|DUF1382-family-protein
MHKASPVELRTSIGMAHSLAQIGVRFVPIPVETDEEFHTLATSLSQKLEMMAAKAEANERDPA
>NZ_CP040309.1|WP_001444000.1|3622727_3623009_+|cell-division-protein-ZapA
MHFSGSRLHILCAYACRHGTCSMTPQQENALRSIARQANSEIKKARQQFPDKNVDDICRSVLKKHRETVTLMGFTPTHLSLAIGMLNGVFKER

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Crispr_ID: NZ_CP040309_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040309_5

4280985-4281197

TypeI-E

I-E

Consensus_repeat	Method
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CRISPRCasFinder
CGGTTTATCCCCGCTGGCGCGGGGAACACA	CRT
CGGTTTATCCCCGCTGGCGCGGGGAACACA	PILER-CR

3 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of NZ_CP040309_5

>merge|NZ_CP040309|5|4280985-4281197|CRISPRCasFinder,CRT,PILER-CR
CGGTTTATCCCCGCTGATGCGGGGAACACAGCGGCACGCTGGATTGAACAAATCCCTGGGCCGGTTTATCCCCGCTGGCGCGGGGAACACAAACCGAAACACACGATCAATCCGAATATGAGCGGTTTATCCCCGCTGGCGCGGGGAACACTTTGGTGACAGTTTTTGTCACTGTTTTGGTGACGGTTTATCCCCGCTGGCGCGGGGAACACA

>NZ_CP040309|5|3|4280985-4281196|CRISPRCasFinder
CGGTTTATCCCCGCTGATGCGGGGAACAC	AGCGGCACGCTGGATTGAACAAATCCCTGGGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AAACCGAAACACACGATCAATCCGAATATGAG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TTTGGTGACAGTTTTTGTCACTGTTTTGGTGA
CGGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP040309|5|1|4280985-4281197|CRT
CGGTTTATCCCCGCTGATGCGGGGAACACA	GCGGCACGCTGGATTGAACAAATCCCTGGGC
CGGTTTATCCCCGCTGGCGCGGGGAACACA	AACCGAAACACACGATCAATCCGAATATGAG
CGGTTTATCCCCGCTGGCGCGGGGAACACT	TTGGTGACAGTTTTTGTCACTGTTTTGGTGA
CGGTTTATCCCCGCTGGCGCGGGGAACACA

>NZ_CP040309|5|3|4281046-4281197|PILER-CR
CGGTTTATCCCCGCTGGCGCGGGGAACACA	AACCGAAACACACGATCAATCCGAATATGAG
CGGTTTATCCCCGCTGGCGCGGGGAACACT	TTGGTGACAGTTTTTGTCACTGTTTTGGTGA
CGGTTTATCCCCGCTGGCGCGGGGAACACA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040309.1\|WP_000246158.1\|4275064_4275775_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
NZ_CP040309.1\|WP_000956458.1\|4290042_4290195_-\|type-I-toxin-antitoxin-system-Hok-family-toxin	unknown	unknown	gnl\|CDD\|366840
NZ_CP040309.1\|WP_001084082.1\|4285491_4287054_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
NZ_CP040309.1\|WP_000029325.1\|4284958_4285495_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09670_cse2gr11_CAS-I-E	gnl\|CDD\|274193
NZ_CP040309.1\|WP_001173673.1\|4276671_4277277_-\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
NZ_CP040309.1\|WP_000206445.1\|4283891_4284947_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	cd09646_cas7_CAS-I-E	gnl\|CDD\|273843
NZ_CP040309.1\|WP_001233978.1\|4287151_4289851_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP040309.1\|WP_000085058.1\|4283134_4283881_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776
NZ_CP040309.1\|WP_000517476.1\|4275793_4276105_-\|cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156
NZ_CP040309.1\|WP_000281463.1\|4282502_4283153_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09664_cas6e_CAS-I-E	gnl\|CDD\|273869
NZ_CP040309.1\|WP_000039864.1\|4290458_4291193_-\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NZ_CP040309.1\|WP_000372111.1\|4278705_4279614_-\|sulfate-adenylyltransferase-subunit-CysD	unknown	unknown	gnl\|CDD\|235375
NZ_CP040309.1\|WP_000063176.1\|4281292_4281586_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930
NZ_CP040309.1\|WP_001090366.1\|4277276_4278704_-\|sulfate-adenylyltransferase-subunit-CysN	unknown	unknown	gnl\|CDD\|235349
NZ_CP040309.1\|WP_001219242.1\|4274585_4275065_-\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851
NZ_CP040309.1\|WP_001295182.1\|4272797_4273559_-\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
NZ_CP040309.1\|WP_000568934.1\|4273539_4274589_-\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884
NZ_CP040309.1\|WP_000144847.1\|4281582_4282506_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NZ_CP040309.1\|WP_001246103.1\|4276298_4276622_-\|DUF3561-family-protein	unknown	unknown	gnl\|CDD\|371891
NZ_CP040309.1\|WP_000490413.1\|4279865_4280903_+\|aminopeptidase	unknown	unknown	gnl\|CDD\|182299

Protein	Function_ID	Function_description	E-value
NZ_CP040309.1\|WP_000246158.1\|4275064_4275775_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	6.38982e-120
NZ_CP040309.1\|WP_000956458.1\|4290042_4290195_-\|type-I-toxin-antitoxin-system-Hok-family-toxin	gnl\|CDD\|366840	pfam01848, HOK_GEF, Hok/gef family.	8.32243e-12
NZ_CP040309.1\|WP_001084082.1\|4285491_4287054_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	0
NZ_CP040309.1\|WP_000029325.1\|4284958_4285495_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|274193	TIGR02548, CRISPR_system_Cascade_subunit_CasB, CRISPR type I-E/ECOLI-associated protein CasB/Cse2. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It was designated Cse2 originally, and renamed CasB based on its characterization in the CASCADE complex.	3.2742e-30
NZ_CP040309.1\|WP_001173673.1\|4276671_4277277_-\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	7.34447e-148
NZ_CP040309.1\|WP_000206445.1\|4283891_4284947_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	2.45802e-155
NZ_CP040309.1\|WP_001233978.1\|4287151_4289851_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	0
NZ_CP040309.1\|WP_000085058.1\|4283134_4283881_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	7.00414e-48
NZ_CP040309.1\|WP_000517476.1\|4275793_4276105_-\|cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	5.55235e-62
NZ_CP040309.1\|WP_000281463.1\|4282502_4283153_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|273869	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1974 from Chlorobium tepidum, is found in the Ecoli subtype of CRISPR/Cas regions and is designated Cse3 (CRISPR/Cas Subtype Ecoli protein 3). The representative of this family from Thermus thermophilus HB8 (TTHB192) has been crystallized and found to have a structure consisting of two domains with opposing parallel beta-sheets known as a beta-sheet platform. This structure is similar to those found in the Sex-lethal protein and poly(A)-binding protein. This structure is consistent with an RNA-binding function.	5.5854e-93
NZ_CP040309.1\|WP_000039864.1\|4290458_4291193_-\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	5.85899e-137
NZ_CP040309.1\|WP_000372111.1\|4278705_4279614_-\|sulfate-adenylyltransferase-subunit-CysD	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
NZ_CP040309.1\|WP_000063176.1\|4281292_4281586_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	2.35543e-65
NZ_CP040309.1\|WP_001090366.1\|4277276_4278704_-\|sulfate-adenylyltransferase-subunit-CysN	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
NZ_CP040309.1\|WP_001219242.1\|4274585_4275065_-\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	1.56248e-104
NZ_CP040309.1\|WP_001295182.1\|4272797_4273559_-\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.92279e-150
NZ_CP040309.1\|WP_000568934.1\|4273539_4274589_-\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0
NZ_CP040309.1\|WP_000144847.1\|4281582_4282506_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	7.06391e-157
NZ_CP040309.1\|WP_001246103.1\|4276298_4276622_-\|DUF3561-family-protein	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	3.44794e-52
NZ_CP040309.1\|WP_000490413.1\|4279865_4280903_+\|aminopeptidase	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0

>NZ_CP040309.1|WP_000490413.1|4279865_4280903_+|aminopeptidase
MFSALRHRTAALALGVCFILPVHASSPKPGDFANTQARHIATFFPGRMTGTPAEMLSADYIRQQFQQMGYRSDIRTFNSRYIYTARDNRKNWHNVTGSTVIAAHEGKAPQQIIIMAHLDTYAPQSDADADANLGGLTLQGMDDNAAGLGVMLELAERLKNTPTEYGIRFVATSGEEEGKLGAENLLKRMSDTEKKNTLLVINLDNLIVGDKLYFNSGVKTPEAVRKLTRDRALAIARSHGIAATTNPGLNKNYPKGTGCCNDAEIFDKAGIAVLSVEATNWNLGNKDGYQQRAKTAAFPAGNSWHDVRLDNQQHIDKALPGRIERRCRDVMRIMLPLVKELAKAS
>NZ_CP040309.1|WP_000372111.1|4278705_4279614_-|sulfate-adenylyltransferase-subunit-CysD
MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHQNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
>NZ_CP040309.1|WP_001090366.1|4277276_4278704_-|sulfate-adenylyltransferase-subunit-CysN
MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYSEETFTRIREDYLTFAGQLPGNLDIRFVPLSALEGDNVASQSESMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRSRVDGIRYQVDINNLTQREVENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAAPSEFSAFELELNALVRRHFPHWGARDLLGEK
>NZ_CP040309.1|WP_001173673.1|4276671_4277277_-|adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
>NZ_CP040309.1|WP_001246103.1|4276298_4276622_-|DUF3561-family-protein
MRNSHNITLTNNDSLTEDEETTWSLPGAVVGFISWLFALAMPMLIYGSNTLFFFIYTWPFFLALMPVAVVVGIALHSLMDGKLRYSIVFTLMTVGIMFGALFMWLLG
>NZ_CP040309.1|WP_000517476.1|4275793_4276105_-|cell-division-protein-FtsB
MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNAKLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNNR
>NZ_CP040309.1|WP_000246158.1|4275064_4275775_-|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVYALLAHPRVKRVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKAAGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEGAAITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQENT
>NZ_CP040309.1|WP_001219242.1|4274585_4275065_-|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
>NZ_CP040309.1|WP_000568934.1|4273539_4274589_-|tRNA-pseudouridine(13)-synthase-TruD
MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHILVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLSAFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYFGAQRFGIGGSNLQGALRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEELVELQRRVNDKELMITAALPGSGEWGTQREALAFEQAAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVVRELINTTGDYAHIAE
>NZ_CP040309.1|WP_001295182.1|4272797_4273559_-|5'/3'-nucleotidase-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINVPDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQDVVSDWLNSVGVGTQW
>NZ_CP040309.1|WP_000063176.1|4281292_4281586_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MSMVVVVTENVPPRLRGRLAIWLLEVRAGVYVGDTSKRIREMIWQQITQLAGCGNVVMAWATNTESGFEFQTWGENRRIPVDLDGLRLVSFLPVDNQ
>NZ_CP040309.1|WP_000144847.1|4281582_4282506_-|type-I-E-CRISPR-associated-endonuclease-Cas1
MTFVPLSPIPLKDRTSMIFLQYGQIDVLDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVHLAATVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQAKLALTEDLRLKVVRKMYELRFREPPPARRSVDQLRGIEGSRVRQTYALLAKQYGVKWNGRKYDPKDWEKGDVVNRCISAATSCLYGISEAAVLAAGYAPAIGFIHSGKPLSFVYDIADIIKFDSVVPKAFEIAARQPAEPDKEVRLACRDIFRSTKLTGKLIPLIEKVLAAGEIEPPQPAPDMLPPAIPEPETLGDSGHRGRGG
>NZ_CP040309.1|WP_000281463.1|4282502_4283153_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSRITLHTGQLSPAQLLHLVDRGEYVMHQWLWDLFPGGKERQFLYRREELQGAFRFFVLSQERPAESETFTIECRSFVPELRTGQQLCFNLRANPTICKAGKRHDLLMEAKRQVRGQAEGSDVWLHQQQAALDWLAAQGERSGFTLLDTSVDAYRQQQLRRENSRQLIQFSSVDYTGMLTVTDPGLFLQRLSQGYGKSRAFGCGLMLIKPGAEV
>NZ_CP040309.1|WP_000085058.1|4283134_4283881_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSQYLIFQLHGPMASWGVDAPGEVRHTHELPSRSALLGLLAAGVGIRRDDTERLNAFNRHYSLVVCASRNPRWARDYHTVQMPKEVRKARYFSRREELSAPDLLSAIISRRDYYTDAWWMVAVATTPDAPYSLEQLQDGLRHPVFPLYLGRKSHPLALPLAPLLLEGNASDVLRNAYQQYQDSFRELKVSLPKLQDECWWEGEHDGLVASKILRRRDVPLNRQQWLFGERTINQGPWLSKEEPCTSQE
>NZ_CP040309.1|WP_000206445.1|4283891_4284947_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGATRLRVSSQSLKRAWRTSALFEQALAGHIGIRSGRIAREAATILIEKGIEEKKAIEWAAKIADYLGKAKNDKKPKDPLTNAETEQLVHISPAEFDAVKALAHQLAEEKRAPKEEDLALLRKDRMAVDIAMFGRMLANKPEFNVEAACQVAHAFGVSETIVEDDFFTAVDDLRQASEDAGAGHLGETGFGSALFYTYICIDKDLLVENLGGDEALANQTLRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTEQPRSLAAAFYEPINGTRQLDVAVQRITTLRENMNTVYEQKTECASFDVMNKQGSMKDVLDFICA
>NZ_CP040309.1|WP_000029325.1|4284958_4285495_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSIVKEEHKATLRKWHEELQEKRGERASLRRSTTVNDVCLTDGFRLFLKNRQIKWQDEPEWRITALALIAALSANVKAIDERLPFAAQLAAVMSKGRFTRLSAVKTPDELLRQLRRVVRLLNGSVNLDSLAEGVFRWCQESDDLLNHHRRHQRPTEFIRIRWALEYYQAGDVDNEQNQ
>NZ_CP040309.1|WP_001084082.1|4285491_4287054_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MNSFSLLTTPWLPVRFKDGTTGKLAPVDLADENVVDIAAPRADLQGAAWQFLLGLLQSSFAPKDYRRWDDIWEDGLEAEKLREALLSLEHPFQFGPDSPSFMQDFEVLMGDKVQVASLLPEIPGAQTTKFNKDHFIKRGVTEHVCSHCSALALFSLQLNAPSGGKGYRTGLRGGGPMTTLIELQEYQGNQQAPLWRKLWLNVMPQDEADLPLPKKFDDLVFPWLGPTRTSELAGAVVTDDQVNKLQAYWGMPRRIRIDFNTTTVGNCDICGEQSDALLSLMTTKNYGANYAMWQHPLTPYRVPLKEGGEFYSVKPQPGGLIWRDWLGLIETGKSENNTELPALVVKLFNASSLKQAKVGLWGFGYDFDNMKARCWYEHHFPLLLNKKEGQIPKLRLAAQTASRILSLLRSALKEAWFSDPKGARGDFSFVDIDFWNKTQHRFLRLVRQIEEGQDADELLGKWQKEIWLFARQDFDERVFTNPYEPVDLERVMTARKKYFTTSAEKQSAKAAREKKQEAAE
>NZ_CP040309.1|WP_001233978.1|4287151_4289851_-|CRISPR-associated-helicase/endonuclease-Cas3
MRKYPLSLLKDKNIVTFFDFWGKTRRGEKEGGDGYHLLCWHSLDVAAMGYLMVKRNCFGLADYFRQLGISDKEQAAQFFAWLLCWHDIGKFARSFQQLYLAPELKIPEGSRKNYEKISHSTLGYWLWNYYLSECEELLPSSSLSSRKLTRVIEMWMSITTGHHGRPPDRIDELDNFLPEDKAAARDFLLEIKALFPLIEIPTFWDDDEGVELLKQLSWYISATVVLADWTGSSTRFFPRVAHPMDIKDYWQKTLVQAQNALTVFPPKAETAPFTGINTLFPFIEHPTPLQQKVLDLDISQPGPQLFILEDVTGAGKTEAALILAHRLMAARKAQGLFFGLPTMATANAMYDRLVKTWLAFYSPESRPSLVLAHSARTLMDRFNESLWSGDLVGSEEPDEQTFSQGCAAWFANSNKKALLAEIGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAYMSCILEGLIERQARGGNSVILLSATLSQQQRDKLVAAFARGTEGQQEAPFLEKDDYPWLTHVTKSDVNSHRVATRKDVERSVSVGWLHSEQESIARIESAVSQGKCIAWIRNSVDDAIKVHRQLLARGVIPASSLSLFHSRFAFSDRQRIEMETLARFGKEDGSQRAGKVLICTQVLEQSVDCDLDEMISDLAPVDLLIQRAGRLQRHIRDINGQLKRDGKDERSPPELLILAPVWDDAPGDEWFGSAMRNSAYVYPDHGRIWLTQRVLREQGAIQMPHAARLLIESVYGEDVVMPEGFARSEQEQVGKYYCDRAMAKKFVLNFKPGYAANINDYLPEKLSTRLAEESVSLWLATCIAGVVKPYATGAHAWEMSVVRVRRSWWKKHRDEFSLLEGEAFRQWCIEQRQDPEMANVILVTDDESCGYSAREGLIGKVD
>NZ_CP040309.1|WP_000956458.1|4290042_4290195_-|type-I-toxin-antitoxin-system-Hok-family-toxin
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK
>NZ_CP040309.1|WP_000039864.1|4290458_4291193_-|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRILALAETNAQLEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKNGLKYHPLWDEGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG

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Crispr_ID: NZ_CP040309_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040309_6

4306827-4306915

Unclear

I-E

Consensus_repeat	Method
GGTTTATCCCCACTGGCGCGGGGAACTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040309_6

>merge|NZ_CP040309|6|4306827-4306915|CRISPRCasFinder
GGTTTATCCCCACTGGCGCGGGGAACTCCTCGACTTTAATTTTTTCGCTGCCCGCTTTTGCGGTTTATCCCCGCTGGCGCGGGGAACTC

>NZ_CP040309|6|4|4306827-4306915|CRISPRCasFinder
GGTTTATCCCCACTGGCGCGGGGAACTC	CTCGACTTTAATTTTTTCGCTGCCCGCTTTTGC
GGTTTATCCCCGCTGGCGCGGGGAACTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040309.1\|WP_001301644.1\|4298655_4299435_-\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	unknown	unknown	gnl\|CDD\|224997
NZ_CP040309.1\|WP_000021347.1\|4302366_4303152_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187605
NZ_CP040309.1\|WP_000059304.1\|4300842_4302297_-\|FAD-linked-oxidoreductase	unknown	unknown	gnl\|CDD\|223354
NZ_CP040309.1\|WP_012779383.1\|4310767_4311682_+\|YgcG-family-protein	unknown	unknown	gnl\|CDD\|224429
NZ_CP040309.1\|WP_001130278.1\|4297075_4297651_+\|glycerol-3-phosphate-responsive-antiterminator	unknown	unknown	gnl\|CDD\|224865
NZ_CP040309.1\|WP_000210878.1\|4313127_4314765_-\|CTP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|235437
NZ_CP040309.1\|WP_000211937.1\|4292978_4294778_-\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	unknown	unknown	gnl\|CDD\|182862
NZ_CP040309.1\|WP_042909427.1\|4308080_4308701_+\|LemA-family-protein	unknown	unknown	gnl\|CDD\|224618
NZ_CP040309.1\|WP_001217990.1\|4309622_4310771_+\|YgcG-family-protein	unknown	unknown	gnl\|CDD\|224429
NZ_CP040309.1\|WP_000254738.1\|4315854_4316190_-\|endoribonuclease-MazF	unknown	unknown	gnl\|CDD\|182138
NZ_CP040309.1\|WP_000581937.1\|4316189_4316438_-\|type-II-toxin-antitoxin-system-antitoxin-MazE	unknown	unknown	gnl\|CDD\|182082
NZ_CP040309.1\|WP_001164582.1\|4303470_4304748_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|349949
NZ_CP040309.1\|WP_000109503.1\|4296798_4297059_+\|ferredoxin-family-protein	unknown	unknown	gnl\|CDD\|225289
NZ_CP040309.1\|WP_001301471.1\|4295536_4296808_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|182194
NZ_CP040309.1\|WP_001071672.1\|4314992_4315784_-\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569
NZ_CP040309.1\|WP_000036723.1\|4311741_4313040_-\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NZ_CP040309.1\|WP_001199973.1\|4307254_4307926_-\|7-carboxy-7-deazaguanine-synthase-QueE	unknown	unknown	gnl\|CDD\|275126
NZ_CP040309.1\|WP_001243487.1\|4308714_4309389_+\|YgcG-family-protein	unknown	unknown	gnl\|CDD\|224429
NZ_CP040309.1\|WP_000039701.1\|4304774_4306253_+\|sugar-kinase	unknown	unknown	gnl\|CDD\|212662
NZ_CP040309.1\|WP_000987944.1\|4295093_4295459_+\|6-carboxytetrahydropterin-synthase-QueD	unknown	unknown	gnl\|CDD\|238264

Protein	Function_ID	Function_description	E-value
NZ_CP040309.1\|WP_001301644.1\|4298655_4299435_-\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	gnl\|CDD\|224997	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion].	1.2806e-65
NZ_CP040309.1\|WP_000021347.1\|4302366_4303152_-\|SDR-family-oxidoreductase	gnl\|CDD\|187605	cd05347, Ga5DH-like_SDR_c, gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs. Ga5DH catalyzes the NADP-dependent conversion of carbon source D-gluconate and 5-keto-D-gluconate. This SDR subgroup has a classical Gly-rich NAD(P)-binding motif and a conserved active site tetrad pattern. However, it has been proposed that Arg104 (Streptococcus suis Ga5DH numbering), as well as an active site Ca2+, play a critical role in catalysis. In addition to Ga5DHs this subgroup contains Erwinia chrysanthemi KduD which is involved in pectin degradation, and is a putative 2,5-diketo-3-deoxygluconate dehydrogenase. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107,15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	2.24046e-138
NZ_CP040309.1\|WP_000059304.1\|4300842_4302297_-\|FAD-linked-oxidoreductase	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	4.96301e-83
NZ_CP040309.1\|WP_012779383.1\|4310767_4311682_+\|YgcG-family-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	1.30872e-104
NZ_CP040309.1\|WP_001130278.1\|4297075_4297651_+\|glycerol-3-phosphate-responsive-antiterminator	gnl\|CDD\|224865	COG1954, GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription].	1.96043e-88
NZ_CP040309.1\|WP_000210878.1\|4313127_4314765_-\|CTP-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NZ_CP040309.1\|WP_000211937.1\|4292978_4294778_-\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	gnl\|CDD\|182862	PRK10953, cysJ, NADPH-dependent assimilatory sulfite reductase flavoprotein subunit.	0
NZ_CP040309.1\|WP_042909427.1\|4308080_4308701_+\|LemA-family-protein	gnl\|CDD\|224618	COG1704, LemA, Uncharacterized conserved protein [Function unknown].	2.13345e-77
NZ_CP040309.1\|WP_001217990.1\|4309622_4310771_+\|YgcG-family-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	5.38776e-66
NZ_CP040309.1\|WP_000254738.1\|4315854_4316190_-\|endoribonuclease-MazF	gnl\|CDD\|182138	PRK09907, PRK09907, endoribonuclease MazF.	1.17475e-74
NZ_CP040309.1\|WP_000581937.1\|4316189_4316438_-\|type-II-toxin-antitoxin-system-antitoxin-MazE	gnl\|CDD\|182082	PRK09798, PRK09798, MazF-MazE toxin-antitoxin system antitoxin MazE.	6.19513e-48
NZ_CP040309.1\|WP_001164582.1\|4303470_4304748_+\|MFS-transporter	gnl\|CDD\|349949	cd06174, MFS, Major Facilitator Superfamily. The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate, while symporters and antiporters transport two substrates in the same or in opposite directions, respectively, across membranes. MFS proteins are typically 400 to 600 amino acids in length, and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members, GlpT (glycerol-3-phosphate transporter), LacY (lactose permease), and EmrD (multidrug transporter), MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake, and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4, which is impaired in type II diabetes, and glucose-6-phosphate transporter (G6PT), which causes glycogen storage disease when mutated.	7.69151e-30
NZ_CP040309.1\|WP_000109503.1\|4296798_4297059_+\|ferredoxin-family-protein	gnl\|CDD\|225289	COG2440, FixX, Ferredoxin-like protein [Energy production and conversion].	1.18571e-41
NZ_CP040309.1\|WP_001301471.1\|4295536_4296808_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|182194	PRK10015, PRK10015, oxidoreductase; Provisional.	4.44674e-126
NZ_CP040309.1\|WP_001071672.1\|4314992_4315784_-\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	1.24402e-159
NZ_CP040309.1\|WP_000036723.1\|4311741_4313040_-\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NZ_CP040309.1\|WP_001199973.1\|4307254_4307926_-\|7-carboxy-7-deazaguanine-synthase-QueE	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	3.98248e-155
NZ_CP040309.1\|WP_001243487.1\|4308714_4309389_+\|YgcG-family-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	3.44494e-83
NZ_CP040309.1\|WP_000039701.1\|4304774_4306253_+\|sugar-kinase	gnl\|CDD\|212662	cd07779, FGGY_ygcE_like, uncharacterized ygcE-like proteins. This subfamily consists of uncharacterized hypothetical bacterial proteins with similarity to Escherichia coli sugar kinase ygcE , whose functional roles are not yet clear. Escherichia coli ygcE is recognized by this model, but is not present in the alignment as it contains a deletion relative to other members of the group. These proteins belong to the FGGY family of carbohydrate kinases, the monomers of which contain two large domains, which are separated by a deep cleft that forms the active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain.	1.25899e-108
NZ_CP040309.1\|WP_000987944.1\|4295093_4295459_+\|6-carboxytetrahydropterin-synthase-QueD	gnl\|CDD\|238264	cd00470, PTPS, 6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a carrier-mediated active transport system. Most microbes and plants lack this system and must synthesize folates de novo from guanosine triphosphate. One enzyme from this pathway is PTPS which catalyzes the conversion of dihydroneopterin triphosphate to 6-pyruvoyl tetrahydropterin. The functional enzyme is a hexamer of identical subunits.	9.8593e-60

>NZ_CP040309.1|WP_000039701.1|4304774_4306253_+|sugar-kinase
MSKKYIIGIDGGSQSTKVVMYDLEGNVVCEGKGLLQPMHTPDADTAEHPDDDLWASLCFAGHDLMSQFAGNKEDIVGIGLGSIRCCRALLKADGTPAAPLISWQDARVTRPYEHTNPDVAYVTSFSGYLTHRLTGEFKDNIANYFGQWPVDYKSWAWSEDAAVMEKFNIPRHMLFDVQMPGTVLGQITPQAALATHFPAGLPVVCTTSDKPVEALGAGLLDDETAVISLGTYIALMMNGKALPKDPVAYWPIMSSIPQTLLYEGYGIRKGMWTVSWLRDMLGESLIQDARAQDLSPEDLLNKKASCVPPGCNGLMTVLDWLTNPWEPYKRGIMIGFDSSMDYAWIYRSILESVALTLKNNYDNMCNEMNHFAKHVIITGGGSNSDLFMQIFADVFNLPARRNAINGCASLGAAINTAVGLGLYPDYATAVDKMVRVKDIFIPIESNAKRYDAMNKGIFKALTKHTDVILKKSYEVMHGELGNADSIQSWSNA
>NZ_CP040309.1|WP_001164582.1|4303470_4304748_+|MFS-transporter
MQHNSYRRWITLAIISFSGGVSFDLAYLRYIYQIPMAKFMGFSNTEIGLIMSTFGIAAIILYAPSGVIADKFSHRKMITSAMIITGLLGLLMATYPPLWVMLCIQVAFAITTILMLWSVSIKAASLLGDHSEQGKIMGWMEGLRGVGVMSLAVFTMWVFSRFAPDDSTSLKTVIIIYSVVYILLGILCWFFVSDNNNLRSANNEEKQSFQLSDILAVLRISTTWYCSMVIFGVFTIYAILSYSTNYLTEMYGMSLVAASYMGIVINKIFRALCGPLGGIITTYSKVKSPTRVIQILSVLGLLALTALLVTNSNPQSVAMGIGLILLLGFTCYASRGLYWACPGEARTPSYIMGTTVGICSVIGFLPDVFVYPIIGHWQDTQPAAEAYRNMWLMGMAALAMVIVFTFLLFQKIRTADSAPAMASSK
>NZ_CP040309.1|WP_000021347.1|4302366_4303152_-|SDR-family-oxidoreductase
MSIESLNAFSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANVFIPSFVKDNGETKEMIENQGVEVDFMQVDITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAYCDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVLDHIPANRWGDTQDLMGAAVFLASQASNYVNGHLLVVDGGYLVR
>NZ_CP040309.1|WP_000059304.1|4300842_4302297_-|FAD-linked-oxidoreductase
MSLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHGIYTLPIPAAVVKLGSTEQVSRVLNFMNAHKINGVPRTGASATEGGLETVVENSVVLDGSAMNQIINIDIENMQATAQCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRSIGQFSTLYGAIEDMVVGLEAVLADGTVTRIKNVPRRAAGPDIRHIIIGNEGALCYITEVTVKIFKFTPENNLFYGYILEDMKTGFNILREIMVEGYRPSIARLYDAEDGTQHFTHFADGKCVLIFMAEGNPRIAKATGEGIAEIVARYPQCQRVDSKLIETWFNNLNWGPDKVAAERVQILKTGNMGFTTEVSGCWSCIHEIYESVINRIRTEFPHADDITMLGGHSSHSYQNGTNMYFVYDYNVVNCKPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWSKLEHGSAWALLEGLKKQFDPNGIMNTGTIYPIEK
>NZ_CP040309.1|WP_001301644.1|4298655_4299435_-|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein
MNILLAFKAEPDAGMLAEKEWQAAAHGNSGPDISLLRSLLGADEQAAAALLLAQRKNGTPMSLTALSMGDERALHWLRYLMALGFEEAVLLETAADLRFASEFVARHIAEWQRQNPLDLIITGCQSSEGQNGQTPFLLAEMLGWPCFTQVERFTLDAPFITLEQRTEHGLRCCRIRLPAVIAVRQCGEVALPVPGMRQRMAAGKAEIIRKTVAAELPAMQCLQLARAEQRRGATLIDGQTVAEKAQKLWQDYLRQRMQP
>NZ_CP040309.1|WP_001130278.1|4297075_4297651_+|glycerol-3-phosphate-responsive-antiterminator
MPLLHLLRQNPVIAAVKDNASLQLAIDSECQFISVLYGNICTISQIVKKIKNAGKYAFIHVDLLEGASNKEVVIQFLKLVTEADGIISTKASMLKAARAEGFFCIHRLFIVDSISFHNIDKQVAQSNPDCIEILPGCMPKVLGWVTEKIRQPLIAGGLVCDEEDARNAINAGVVALSTTNTGVWTLAKKLL
>NZ_CP040309.1|WP_000109503.1|4296798_4297059_+|ferredoxin-family-protein
MSVARNLWRAADAPHIVPADSVERQMVQRLINACPVGLFSLTPEGDLRVDYHGCLECGTCRLLCDESTLQQWRYPPSGFGITYRFG
>NZ_CP040309.1|WP_001301471.1|4295536_4296808_+|FAD-dependent-oxidoreductase
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQFHLTAPLERRITHESLSLLTPDCATTFSSLQPGGESWSVLRARFDPWLVAEAEKEGVECIPGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVLAERHGLVTRPAGEAMALGIKEVLSLETSAIEERFHLENNEGAALLFSGGICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQSRVPASELLARFKTHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDALRSCVNTGISVRGMDTALTGAQAAAQTLISACQHREPQNLFPLYHHNVERSLLWDVLQRYQHVPVLLQRPGWYRTWPALMQDISRDLWDQGDKPVPPLRQLLWRHLRRHGLWNLAGDVIRSVRCL
>NZ_CP040309.1|WP_000987944.1|4295093_4295459_+|6-carboxytetrahydropterin-synthase-QueD
MMSTTLFKDFTFEAAHRLPHVPEGHKCGRLHGHSFMVRLEITGEVDPHTGWIIDFAELKAAFKPTYERLDHHYLNDIPGLENPTSEVLAKWIWDQVKPVVPLLSAVMVKETCTAGCIYRGE
>NZ_CP040309.1|WP_000211937.1|4292978_4294778_-|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit
MTTQVPPSALLPLNPEQLARLQAATTDLTPTQLAWVSGYFWGVLNQQPAALAATPAPAAEMPGITIISASQTGNARRVAEALRDDLLTAKLNVKLVNAGDYKFKQIASEKLLIVVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDSSYEFFCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDALKSRAPVAAPSQSVATGVVNEIHTSPYSKDAPLVASLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDALGVWYQNDPALVKELVELLWLKGDEPVTVEGKTLPLNEALQWHFELTVNTANIVENYATLTRSETLLPLVGDKAKLQHYAATTPIVDMVRFSPAQLDAEALINLLRPLTPRLYSIASSQEEVENEVHVTVGVVRYDVEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPANPETPVIMIGPGTGIAPFRAFMQQRAADEAPGKNWLFFGNPHFTEDFLYQVEWQRYVKEGVLTRIDLAWSRDQKEKVYVQDKLREQGAELWRWINDGAHIYVCGDANRMAKDVEQALLEVIAEFGGMDTEAADEFLSELRVERRYQRDVY
>NZ_CP040309.1|WP_001199973.1|4307254_4307926_-|7-carboxy-7-deazaguanine-synthase-QueE
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWEKLEDREVSLFSILAKTKESDKWGAASSEDLLAVIGRQGYTARHVVITGGEPCIHDLLPLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYEVLSQALERANEIKHPVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIARNWRLSMQTHKYLNIA
>NZ_CP040309.1|WP_042909427.1|4308080_4308701_+|LemA-family-protein
MKRDLNTLRIFIVIIFIFNLSGCGYNDIQTYDEQVNASWSEVLNQYQRRADLIPNLVASIKGYSSHERDVLEAVTLARSQANRASSDLQQTPGDEQKLQAWQQAQAQVTRTLGQLTIISERYPELKSQELYQNLMVQLEGSENRIAVARGRYIKAIEQYNVTIRKFPAVLTAKVMDYTPKKNYLPDDVAAVSKAPTIDFSQNANAH
>NZ_CP040309.1|WP_001243487.1|4308714_4309389_+|YgcG-family-protein
MRNFIFLMAFFCSSVFATQIPVPESPKYVNDLTGTLTNSEVNTLTNQIKALTQKNYAQLVVLVVETTGDETIEQYATRVFDSWKPGDKDRDDGVLLLVAWQDHTVRIEIGYGLEGIITDAQSGKIIRNSIIPAFKKGDLAGGLQKGISDIESRLTGNNLATITPTDHPLPFSGWWALLVWAIVLTFISARGYIKTLGVICFAAIVLAFVLPIAGFSGSWGVLAT
>NZ_CP040309.1|WP_001217990.1|4309622_4310771_+|YgcG-family-protein
MRIFLLLLMLCGFQVFAERLPSVTDLTGTLTTEEQTALTQQLQTLEQQNHFQVAVLVTPTTGGKNIKLAASQRYGVYHWKPVGEKRYGEGILILVVWPEGLASMKIGHGLEEMLPPEQAAQIVRYHMQPEFEKNNLFAGLTGGIESIAQFTHIKANLSPLDALANHLFANPQRSLPCLAWTLLMIVAIVVLWLFASRPRRGIWMISMITPMVWFFSFQDDVIIRRVSVVCFSLLLATTCKQRLAVVFNMCRVFPMMLTPKNKNAKVKKQKKTPQVRESGRNSLFVVMLIIIVGWCLVFASNKDIAFISTIIGLIDHFIGPITIAGIVLLIIVAKFTGNLKLGSGEKSNRKTGNRNAHSRSSSRNSFRGGGGSSGGGGSSVRW
>NZ_CP040309.1|WP_012779383.1|4310767_4311682_+|YgcG-family-protein
MIVMRLIFILFTLWCLPGLAQQIAVPELRQQVTDITGTLSTSEQQSLTQQLQDITHKTRAQVAVLVVPSTGDDSIEQYATRVFDSWKLGDKQRNDGILLLVAWEDHAVRIEVGYGLEGVVTDLQAAKIIRDILIPAFKSDDLMGGLTLASENIGALLLNGELPEDRGDYYSINPPIPLSLAVIILLAVLSYFIVFTDPSNLPWITLTGAIYGMVFLYVAEPGPWTNLIVACGMLTPFAIVPLVIFWLIVNKKLRAKYKKLSKDRASRKGSSSSSSGGGSSGGGSGGGFSGGGGSSGGGGASGRW
>NZ_CP040309.1|WP_000036723.1|4311741_4313040_-|phosphopyruvate-hydratase
MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>NZ_CP040309.1|WP_000210878.1|4313127_4314765_-|CTP-synthase-(glutamine-hydrolyzing)
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK
>NZ_CP040309.1|WP_001071672.1|4314992_4315784_-|nucleoside-triphosphate-pyrophosphohydrolase
MNQIDRLLTIMQRLRDPENGCPWDKEQTFATITPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFADSSAENSSEVLARWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWTTLGPVVDKVYEEIDEVMYEARQAVVDQAKLEEEMGDLLFATVNLARHLGTKAEIALQKANEKFERRFREVERIVAARGLEMTGVDLETMEEVWQQVKRQEIDL
>NZ_CP040309.1|WP_000254738.1|4315854_4316190_-|endoribonuclease-MazF
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
>NZ_CP040309.1|WP_000581937.1|4316189_4316438_-|type-II-toxin-antitoxin-system-antitoxin-MazE
MIHSSVKRWGNSPAVRIPATLMQALNLNIDDEVKIDLVDGKLIIEPVRKEPVFTLAELVNDITPENLHENIDWGEPKDKEVW

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP040309_4	4.2\|3615951\|26\|NZ_CP040309\|PILER-CR	3615951-3615976	26	NZ_CP040309.1	2322288-2322313	0	1.0

1. spacer 4.2|3615951|26|NZ_CP040309|PILER-CR matches to position: 2322288-2322313, mismatch: 0, identity: 1.0

atttacctctttcaggtaaactttat	CRISPR spacer
atttacctctttcaggtaaactttat	Protospacer
**************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP040309_2	2.2\|799562\|42\|NZ_CP040309\|PILER-CR	799562-799603	42	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	141085-141126	0	1.0
NZ_CP040309_4	4.1\|3615904\|25\|NZ_CP040309\|PILER-CR	3615904-3615928	25	NZ_AP023208	Escherichia coli strain TUM18781 plasmid pMTY18781-3, complete sequence	44572-44596	0	1.0
NZ_CP040309_4	4.2\|3615951\|26\|NZ_CP040309\|PILER-CR	3615951-3615976	26	NC_049946	Escherichia virus Lambda_4A7 genome assembly, chromosome: 1	37604-37629	0	1.0
NZ_CP040309_4	4.2\|3615951\|26\|NZ_CP040309\|PILER-CR	3615951-3615976	26	LR595861	Escherichia virus Lambda_4C10 genome assembly, chromosome: 1	37887-37912	0	1.0
NZ_CP040309_4	4.2\|3615951\|26\|NZ_CP040309\|PILER-CR	3615951-3615976	26	NZ_AP023208	Escherichia coli strain TUM18781 plasmid pMTY18781-3, complete sequence	44524-44549	1	0.962
NZ_CP040309_5	5.3\|4281136\|32\|NZ_CP040309\|CRISPRCasFinder	4281136-4281167	32	MK047640	Phage NV18, complete genome	15645-15676	1	0.969
NZ_CP040309_5	5.6\|4281137\|31\|NZ_CP040309\|CRT,PILER-CR	4281137-4281167	31	MK047640	Phage NV18, complete genome	15646-15676	1	0.968
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	101196-101230	2	0.943
NZ_CP040309_4	4.1\|3615904\|25\|NZ_CP040309\|PILER-CR	3615904-3615928	25	NC_049946	Escherichia virus Lambda_4A7 genome assembly, chromosome: 1	37652-37676	2	0.92
NZ_CP040309_4	4.1\|3615904\|25\|NZ_CP040309\|PILER-CR	3615904-3615928	25	LR595861	Escherichia virus Lambda_4C10 genome assembly, chromosome: 1	37935-37959	2	0.92
NZ_CP040309_5	5.3\|4281136\|32\|NZ_CP040309\|CRISPRCasFinder	4281136-4281167	32	MF417881	Uncultured Caudovirales phage clone 7AX_3, partial genome	2718-2749	2	0.938
NZ_CP040309_5	5.6\|4281137\|31\|NZ_CP040309\|CRT,PILER-CR	4281137-4281167	31	MF417881	Uncultured Caudovirales phage clone 7AX_3, partial genome	2718-2748	2	0.935
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	165464-165498	3	0.914
NZ_CP040309_4	4.2\|3615951\|26\|NZ_CP040309\|PILER-CR	3615951-3615976	26	NZ_CP015341	Lactobacillus brevis strain 100D8 plasmid unnamed3, complete sequence	35661-35686	4	0.846
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP048307	Escherichia coli strain 9 plasmid p009_C, complete sequence	14239-14273	5	0.857
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP044308	Escherichia coli strain C27A plasmid pC27A-3, complete sequence	56080-56114	5	0.857
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	6804-6838	6	0.829
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	208981-209015	6	0.829
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	219475-219509	6	0.829
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	210309-210343	6	0.829
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	191264-191298	6	0.829
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP010208	Escherichia coli strain M11 plasmid B, complete sequence	30177-30211	6	0.829
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	MT230312	Escherichia coli strain DH5alpha plasmid pESBL31, complete sequence	170-204	6	0.829
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_AP023209	Escherichia coli strain TUM18781 plasmid pMTY18781-4, complete sequence	88-122	6	0.829
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	87137-87171	7	0.8
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	138033-138067	7	0.8
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	43-77	7	0.8
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	3372-3406	7	0.8
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	208887-208921	7	0.8
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	42-76	7	0.8
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	3371-3405	7	0.8
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	219381-219415	7	0.8
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	42-76	7	0.8
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	3371-3405	7	0.8
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	210215-210249	7	0.8
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	42-76	7	0.8
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	3371-3405	7	0.8
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	191170-191204	7	0.8
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP010208	Escherichia coli strain M11 plasmid B, complete sequence	27246-27280	7	0.8
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP044307	Escherichia coli strain C27A plasmid pC27A-2, complete sequence	18350-18384	7	0.8
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP044307	Escherichia coli strain C27A plasmid pC27A-2, complete sequence	15018-15052	7	0.8
NZ_CP040309_5	5.4\|4281015\|31\|NZ_CP040309\|CRT	4281015-4281045	31	NC_015512	Haliscomenobacter hydrossis DSM 1100 plasmid pHALHY02, complete sequence	90200-90230	7	0.774
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	61916-61950	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	4114-4148	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229148-229182	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229249-229283	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229350-229384	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229451-229485	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	203852-203886	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	204038-204072	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	204131-204165	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	4113-4147	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239642-239676	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239743-239777	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239844-239878	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239945-239979	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	214346-214380	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	214532-214566	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	214625-214659	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	4113-4147	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230554-230588	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230655-230689	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230756-230790	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230857-230891	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	205180-205214	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	205366-205400	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	205459-205493	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	4113-4147	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211524-211558	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211625-211659	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211726-211760	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211827-211861	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	186135-186169	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	186321-186355	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	186414-186448	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP044307	Escherichia coli strain C27A plasmid pC27A-2, complete sequence	14272-14306	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP044147	Escherichia coli O157 strain AR-0428 plasmid pAR-0428-2	6744-6778	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP044147	Escherichia coli O157 strain AR-0428 plasmid pAR-0428-2	7392-7426	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	CP044351	Escherichia coli strain 194195 plasmid p194195_1, complete sequence	83590-83624	8	0.771
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	CP044351	Escherichia coli strain 194195 plasmid p194195_1, complete sequence	84216-84250	8	0.771
NZ_CP040309_5	5.1\|4281014\|32\|NZ_CP040309\|CRISPRCasFinder	4281014-4281045	32	NC_015512	Haliscomenobacter hydrossis DSM 1100 plasmid pHALHY02, complete sequence	90200-90231	8	0.75
NZ_CP040309_5	5.6\|4281137\|31\|NZ_CP040309\|CRT,PILER-CR	4281137-4281167	31	NC_011370	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG203, complete sequence	102901-102931	8	0.742
NZ_CP040309_5	5.6\|4281137\|31\|NZ_CP040309\|CRT,PILER-CR	4281137-4281167	31	NZ_CP032697	Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525a, complete sequence	313484-313514	8	0.742
NZ_CP040309_5	5.6\|4281137\|31\|NZ_CP040309\|CRT,PILER-CR	4281137-4281167	31	NZ_CP049249	Rhizobium rhizoryzae strain DSM 29514 plasmid unnamed3, complete sequence	984473-984503	8	0.742
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	386558-386592	9	0.743
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	4013-4047	9	0.743
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	4012-4046	9	0.743
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	4012-4046	9	0.743
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	4012-4046	9	0.743
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP044308	Escherichia coli strain C27A plasmid pC27A-3, complete sequence	13988-14022	9	0.743
NZ_CP040309_3	3.1\|824439\|35\|NZ_CP040309\|CRISPRCasFinder	824439-824473	35	NZ_CP019246	Escherichia coli strain Combat13F7 plasmid pCombat13F7-1, complete sequence	41415-41449	9	0.743
NZ_CP040309_5	5.3\|4281136\|32\|NZ_CP040309\|CRISPRCasFinder	4281136-4281167	32	NC_011370	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG203, complete sequence	102900-102931	9	0.719
NZ_CP040309_5	5.3\|4281136\|32\|NZ_CP040309\|CRISPRCasFinder	4281136-4281167	32	NZ_CP032697	Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525a, complete sequence	313483-313514	9	0.719
NZ_CP040309_5	5.3\|4281136\|32\|NZ_CP040309\|CRISPRCasFinder	4281136-4281167	32	NZ_CP049249	Rhizobium rhizoryzae strain DSM 29514 plasmid unnamed3, complete sequence	984472-984503	9	0.719

1. spacer 2.2|799562|42|NZ_CP040309|PILER-CR matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 0, identity: 1.0

gaacttaacaatattgaaagttggatttatctgcgtgtgaca	CRISPR spacer
gaacttaacaatattgaaagttggatttatctgcgtgtgaca	Protospacer
******************************************

2. spacer 4.1|3615904|25|NZ_CP040309|PILER-CR matches to NZ_AP023208 (Escherichia coli strain TUM18781 plasmid pMTY18781-3, complete sequence) position: , mismatch: 0, identity: 1.0

gtgcctttacctgatttgggtaaac	CRISPR spacer
gtgcctttacctgatttgggtaaac	Protospacer
*************************

3. spacer 4.2|3615951|26|NZ_CP040309|PILER-CR matches to NC_049946 (Escherichia virus Lambda_4A7 genome assembly, chromosome: 1) position: , mismatch: 0, identity: 1.0

atttacctctttcaggtaaactttat	CRISPR spacer
atttacctctttcaggtaaactttat	Protospacer
**************************

4. spacer 4.2|3615951|26|NZ_CP040309|PILER-CR matches to LR595861 (Escherichia virus Lambda_4C10 genome assembly, chromosome: 1) position: , mismatch: 0, identity: 1.0

atttacctctttcaggtaaactttat	CRISPR spacer
atttacctctttcaggtaaactttat	Protospacer
**************************

5. spacer 4.2|3615951|26|NZ_CP040309|PILER-CR matches to NZ_AP023208 (Escherichia coli strain TUM18781 plasmid pMTY18781-3, complete sequence) position: , mismatch: 1, identity: 0.962

atttacctctttcaggtaaactttat	CRISPR spacer
atttacctctttaaggtaaactttat	Protospacer
************ *************

6. spacer 5.3|4281136|32|NZ_CP040309|CRISPRCasFinder matches to MK047640 (Phage NV18, complete genome) position: , mismatch: 1, identity: 0.969

tttggtgacagtttttgtcactgttttggtga	CRISPR spacer
tttggtgacactttttgtcactgttttggtga	Protospacer
********** *********************

7. spacer 5.6|4281137|31|NZ_CP040309|CRT,PILER-CR matches to MK047640 (Phage NV18, complete genome) position: , mismatch: 1, identity: 0.968

ttggtgacagtttttgtcactgttttggtga	CRISPR spacer
ttggtgacactttttgtcactgttttggtga	Protospacer
********* *********************

8. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 2, identity: 0.943

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgccagcgtcgcatcaggcgctgaa	Protospacer
 ***********.**********************

9. spacer 4.1|3615904|25|NZ_CP040309|PILER-CR matches to NC_049946 (Escherichia virus Lambda_4A7 genome assembly, chromosome: 1) position: , mismatch: 2, identity: 0.92

gtgcctttacctgatttgggtaaac	CRISPR spacer
acgcctttacctgatttgggtaaac	Protospacer
..***********************

10. spacer 4.1|3615904|25|NZ_CP040309|PILER-CR matches to LR595861 (Escherichia virus Lambda_4C10 genome assembly, chromosome: 1) position: , mismatch: 2, identity: 0.92

gtgcctttacctgatttgggtaaac	CRISPR spacer
acgcctttacctgatttgggtaaac	Protospacer
..***********************

11. spacer 5.3|4281136|32|NZ_CP040309|CRISPRCasFinder matches to MF417881 (Uncultured Caudovirales phage clone 7AX_3, partial genome) position: , mismatch: 2, identity: 0.938

tttggtgacagtttttgtcactgttttggtga	CRISPR spacer
tttggtgacactttttgtcactgatttggtga	Protospacer
********** ************ ********

12. spacer 5.6|4281137|31|NZ_CP040309|CRT,PILER-CR matches to MF417881 (Uncultured Caudovirales phage clone 7AX_3, partial genome) position: , mismatch: 2, identity: 0.935

ttggtgacagtttttgtcactgttttggtga	CRISPR spacer
ttggtgacactttttgtcactgatttggtga	Protospacer
********* ************ ********

13. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 3, identity: 0.914

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
agataagacgcgtcagcgtcgcatcaggcgttaca	Protospacer
******************************.*. *

14. spacer 4.2|3615951|26|NZ_CP040309|PILER-CR matches to NZ_CP015341 (Lactobacillus brevis strain 100D8 plasmid unnamed3, complete sequence) position: , mismatch: 4, identity: 0.846

atttacctctttcaggtaaactttat	CRISPR spacer
aggtatctcattcaggtaaactttat	Protospacer
*  **.*** ****************

15. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP048307 (Escherichia coli strain 9 plasmid p009_C, complete sequence) position: , mismatch: 5, identity: 0.857

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgacagcggcgcatcaggcgctggt	Protospacer
 *********** ***** **************.

16. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP044308 (Escherichia coli strain C27A plasmid pC27A-3, complete sequence) position: , mismatch: 5, identity: 0.857

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
cgctaagacgcgccagcgtcgcatcaggcgttgag	Protospacer
 * *********.*****************.***.

17. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 6, identity: 0.829

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
agataagacgcgtcagcgtcgcatctggcataaac	Protospacer
************************* ***.. .*

18. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 6, identity: 0.829

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgtcagcgtcgcatcaggcatctga	Protospacer
 ****************************... .*

19. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 6, identity: 0.829

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgtcagcgtcgcatcaggcatctga	Protospacer
 ****************************... .*

20. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 6, identity: 0.829

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgtcagcgtcgcatcaggcatctga	Protospacer
 ****************************... .*

21. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 6, identity: 0.829

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgtcagcgtcgcatcaggcatctga	Protospacer
 ****************************... .*

22. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP010208 (Escherichia coli strain M11 plasmid B, complete sequence) position: , mismatch: 6, identity: 0.829

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgtcagcgtcgcatcaggcatcaga	Protospacer
 ****************************.....*

23. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to MT230312 (Escherichia coli strain DH5alpha plasmid pESBL31, complete sequence) position: , mismatch: 6, identity: 0.829

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgtcagcgtcgcatcaggcttcaat	Protospacer
 **************************** ...*

24. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_AP023209 (Escherichia coli strain TUM18781 plasmid pMTY18781-4, complete sequence) position: , mismatch: 6, identity: 0.829

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgtcagcgtcgcatcaggcatcggc	Protospacer
 ****************************...*.

25. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 7, identity: 0.8

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcggcagcgtcgcatcaggcatcgtg	Protospacer
 *********** ****************...* .

26. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 7, identity: 0.8

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcattagcgtcgcatcaggcagcgca	Protospacer
 **********.*.***************. .* *

27. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 7, identity: 0.8

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgtcagcgtcgcatcaggcatcagc	Protospacer
 ****************************.....

28. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 7, identity: 0.8

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgccagcgtcgcatcaggcacctgc	Protospacer
 ***********.****************.*. .

29. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 7, identity: 0.8

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataaaacgcgtcagcgtcgcatcaggcatcggc	Protospacer
 *****.**********************...*.

30. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 7, identity: 0.8

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgtcagcgtcgcatcaggcatcagc	Protospacer
 ****************************.....

31. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 7, identity: 0.8

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgccagcgtcgcatcaggcacctgc	Protospacer
 ***********.****************.*. .

32. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 7, identity: 0.8

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataaaacgcgtcagcgtcgcatcaggcatcggc	Protospacer
 *****.**********************...*.

33. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 7, identity: 0.8

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgtcagcgtcgcatcaggcatcagc	Protospacer
 ****************************.....

34. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 7, identity: 0.8

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgccagcgtcgcatcaggcacctgc	Protospacer
 ***********.****************.*. .

35. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 7, identity: 0.8

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataaaacgcgtcagcgtcgcatcaggcatcggc	Protospacer
 *****.**********************...*.

36. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 7, identity: 0.8

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgtcagcgtcgcatcaggcatcagc	Protospacer
 ****************************.....

37. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 7, identity: 0.8

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgccagcgtcgcatcaggcacctgc	Protospacer
 ***********.****************.*. .

38. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 7, identity: 0.8

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataaaacgcgtcagcgtcgcatcaggcatcggc	Protospacer
 *****.**********************...*.

39. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP010208 (Escherichia coli strain M11 plasmid B, complete sequence) position: , mismatch: 7, identity: 0.8

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgtctgcgtcgcatctggcaccggt	Protospacer
 ************* ********** ***.*.*.

40. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP044307 (Escherichia coli strain C27A plasmid pC27A-2, complete sequence) position: , mismatch: 7, identity: 0.8

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgtcagcgtcgcatcaggcatcagc	Protospacer
 ****************************.....

41. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP044307 (Escherichia coli strain C27A plasmid pC27A-2, complete sequence) position: , mismatch: 7, identity: 0.8

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgccagcgtcgcatcaggcacctgg	Protospacer
 ***********.****************.*. ..

42. spacer 5.4|4281015|31|NZ_CP040309|CRT matches to NC_015512 (Haliscomenobacter hydrossis DSM 1100 plasmid pHALHY02, complete sequence) position: , mismatch: 7, identity: 0.774

gcggcacgctggattgaacaaat---ccctgggc	CRISPR spacer
gcggcacgatgggttgaacaaatggactttg---	Protospacer
******** ***.**********   *..**

43. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
agataagacgcgccagcgtcgcatctggcatctgc	Protospacer
************.************ ***... .

44. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgccagcgtcgcatcaggcatctgc	Protospacer
 ***********.****************... .

45. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgttagcgtcgcatcaggcatctgc	Protospacer
 ************.***************... .

46. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgttagcgtcgcatcaggcatctgc	Protospacer
 ************.***************... .

47. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgttagcgtcgcatcaggcatctgc	Protospacer
 ************.***************... .

48. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgttagcgtcgcatcaggcatctgc	Protospacer
 ************.***************... .

49. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagtcgcgtcagcgacgcatcaggcatcggc	Protospacer
 ****** ********** **********...*.

50. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagtcgcgtcagcggcgcatcaggcatcggt	Protospacer
 ****** ********** **********...*.

51. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagtcgcgtcagcggcgcatcaggcatcggt	Protospacer
 ****** ********** **********...*.

52. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgccagcgtcgcatcaggcatctgc	Protospacer
 ***********.****************... .

53. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgttagcgtcgcatcaggcatctgc	Protospacer
 ************.***************... .

54. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgttagcgtcgcatcaggcatctgc	Protospacer
 ************.***************... .

55. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgttagcgtcgcatcaggcatctgc	Protospacer
 ************.***************... .

56. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgttagcgtcgcatcaggcatctgc	Protospacer
 ************.***************... .

57. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagtcgcgtcagcgacgcatcaggcatcggc	Protospacer
 ****** ********** **********...*.

58. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagtcgcgtcagcggcgcatcaggcatcggt	Protospacer
 ****** ********** **********...*.

59. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagtcgcgtcagcggcgcatcaggcatcggt	Protospacer
 ****** ********** **********...*.

60. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgccagcgtcgcatcaggcatctgc	Protospacer
 ***********.****************... .

61. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgttagcgtcgcatcaggcatctgc	Protospacer
 ************.***************... .

62. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgttagcgtcgcatcaggcatctgc	Protospacer
 ************.***************... .

63. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgttagcgtcgcatcaggcatctgc	Protospacer
 ************.***************... .

64. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgttagcgtcgcatcaggcatctgc	Protospacer
 ************.***************... .

65. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagtcgcgtcagcgacgcatcaggcatcggc	Protospacer
 ****** ********** **********...*.

66. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagtcgcgtcagcggcgcatcaggcatcggt	Protospacer
 ****** ********** **********...*.

67. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagtcgcgtcagcggcgcatcaggcatcggt	Protospacer
 ****** ********** **********...*.

68. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgccagcgtcgcatcaggcatctgc	Protospacer
 ***********.****************... .

69. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgttagcgtcgcatcaggcatctgc	Protospacer
 ************.***************... .

70. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgttagcgtcgcatcaggcatctgc	Protospacer
 ************.***************... .

71. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgttagcgtcgcatcaggcatctgc	Protospacer
 ************.***************... .

72. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgttagcgtcgcatcaggcatctgc	Protospacer
 ************.***************... .

73. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagtcgcgtcagcgacgcatcaggcatcggc	Protospacer
 ****** ********** **********...*.

74. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagtcgcgtcagcggcgcatcaggcatcggt	Protospacer
 ****** ********** **********...*.

75. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagtcgcgtcagcggcgcatcaggcatcggt	Protospacer
 ****** ********** **********...*.

76. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP044307 (Escherichia coli strain C27A plasmid pC27A-2, complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagatgcgccagcgtcgcatcaggtaattca	Protospacer
 *******.***.***************.. *  *

77. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP044147 (Escherichia coli O157 strain AR-0428 plasmid pAR-0428-2) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgtcagcgtcgtatcaggcatctgc	Protospacer
 ********************.*******... .

78. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP044147 (Escherichia coli O157 strain AR-0428 plasmid pAR-0428-2) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgccagcgtcgcatcaggcatccgg	Protospacer
 ***********.****************... ..

79. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to CP044351 (Escherichia coli strain 194195 plasmid p194195_1, complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgtcagcgtcgtatcaggcatctgc	Protospacer
 ********************.*******... .

80. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to CP044351 (Escherichia coli strain 194195 plasmid p194195_1, complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgccagcgtcgcatcaggcatccgg	Protospacer
 ***********.****************... ..

81. spacer 5.1|4281014|32|NZ_CP040309|CRISPRCasFinder matches to NC_015512 (Haliscomenobacter hydrossis DSM 1100 plasmid pHALHY02, complete sequence) position: , mismatch: 8, identity: 0.75

agcggcacgctggattgaacaaat---ccctgggc	CRISPR spacer
tgcggcacgatgggttgaacaaatggactttg---	Protospacer
 ******** ***.**********   *..**

82. spacer 5.6|4281137|31|NZ_CP040309|CRT,PILER-CR matches to NC_011370 (Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG203, complete sequence) position: , mismatch: 8, identity: 0.742

ttggtgacagtttttgtcactgttttggtga	CRISPR spacer
cagtcaagagtctttggcactgttttggtga	Protospacer
. * ..* ***.**** **************

83. spacer 5.6|4281137|31|NZ_CP040309|CRT,PILER-CR matches to NZ_CP032697 (Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525a, complete sequence) position: , mismatch: 8, identity: 0.742

ttggtgacagtttttgtcactgttttggtga	CRISPR spacer
cagtcaagagtctttggcactgttttggtga	Protospacer
. * ..* ***.**** **************

84. spacer 5.6|4281137|31|NZ_CP040309|CRT,PILER-CR matches to NZ_CP049249 (Rhizobium rhizoryzae strain DSM 29514 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.742

ttggtgacagtttttgtcactgttttggtga	CRISPR spacer
cagtcaagagtttttggcaccgttttggtga	Protospacer
. * ..* ******** ***.**********

85. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 9, identity: 0.743

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgttagcatcgcatcaggcatcagc	Protospacer
 ************.***.***********.....

86. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 9, identity: 0.743

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgctagcgtcgcatcaggcatctgc	Protospacer
 ***********..***************... .

87. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 9, identity: 0.743

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgctagcgtcgcatcaggcatctgc	Protospacer
 ***********..***************... .

88. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 9, identity: 0.743

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgctagcgtcgcatcaggcatctgc	Protospacer
 ***********..***************... .

89. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 9, identity: 0.743

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgctagcgtcgcatcaggcatctgc	Protospacer
 ***********..***************... .

90. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP044308 (Escherichia coli strain C27A plasmid pC27A-3, complete sequence) position: , mismatch: 9, identity: 0.743

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
cgataagacgcgccagcgtcgcatcgggcatccgt	Protospacer
 ***********.************.***... .

91. spacer 3.1|824439|35|NZ_CP040309|CRISPRCasFinder matches to NZ_CP019246 (Escherichia coli strain Combat13F7 plasmid pCombat13F7-1, complete sequence) position: , mismatch: 9, identity: 0.743

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgccagcgtcgcatcagacatcagc	Protospacer
 ***********.**************.*.....

92. spacer 5.3|4281136|32|NZ_CP040309|CRISPRCasFinder matches to NC_011370 (Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG203, complete sequence) position: , mismatch: 9, identity: 0.719

tttggtgacagtttttgtcactgttttggtga	CRISPR spacer
acagtcaagagtctttggcactgttttggtga	Protospacer
 . * ..* ***.**** **************

93. spacer 5.3|4281136|32|NZ_CP040309|CRISPRCasFinder matches to NZ_CP032697 (Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525a, complete sequence) position: , mismatch: 9, identity: 0.719

tttggtgacagtttttgtcactgttttggtga	CRISPR spacer
gcagtcaagagtctttggcactgttttggtga	Protospacer
 . * ..* ***.**** **************

94. spacer 5.3|4281136|32|NZ_CP040309|CRISPRCasFinder matches to NZ_CP049249 (Rhizobium rhizoryzae strain DSM 29514 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.719

tttggtgacagtttttgtcactgttttggtga	CRISPR spacer
gcagtcaagagtttttggcaccgttttggtga	Protospacer
 . * ..* ******** ***.**********

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

357247 : 371912

Enterobacteria_phage(40.0%)

integrase,tail,tRNA

attL 358528:358543|attR 376057:376072

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000956557.1\|357247_357781_+	hypothetical protein	K7PKJ4	Enterobacteria_phage	1.1e-99	100.0
WP_001093918.1\|358198_358480_-	hypothetical protein	K7PGU0	Enterobacteria_phage	8.7e-45	98.9
358528:358543	attL	NA	NA	NA	NA
WP_000829415.1\|358824_359022_-	hypothetical protein	K7PH57	Enterobacteria_phage	7.5e-11	68.6
WP_000145668.1\|359357_359642_-	hypothetical protein	I6S1S6	Salmonella_phage	1.3e-40	83.9
WP_001242740.1\|359638_359989_-	hypothetical protein	A0A0P0ZBF8	Stx2-converting_phage	1.6e-56	94.8
WP_000008211.1\|359979_360516_-	5'-deoxynucleotidase	U5P0T3	Shigella_phage	3.1e-99	98.3
WP_001230514.1\|361837_362437_+	Ail/Lom family protein	A0A0P0ZE39	Stx2-converting_phage	5.7e-110	99.0
WP_000268945.1\|362501_363815_+\|tail	tail fiber protein	A0A0P0ZE15	Stx2-converting_phage	2.5e-81	98.2
WP_001023355.1\|363816_364086_+\|tail	phage tail protein	A0A0P0ZEF0	Stx2-converting_phage	2.7e-43	96.6
WP_001118000.1\|364197_364770_+	DUF1076 domain-containing protein	H6WZN1	Escherichia_phage	2.5e-46	53.2
WP_072140863.1\|364842_365472_+	DUF1076 domain-containing protein	B6DZB9	Enterobacteria_phage	1.4e-79	93.5
WP_001143816.1\|365553_366195_+	DUF1076 domain-containing protein	B6DZC0	Enterobacteria_phage	1.1e-106	99.1
WP_001217541.1\|366355_366604_-	DinI-like family protein	A5LH55	Enterobacteria_phage	3.1e-38	98.8
WP_000332269.1\|366665_367763_-\|integrase	site-specific integrase	S5MDN5	Escherichia_phage	2.1e-211	99.5
WP_000543819.1\|367851_368889_+\|tRNA	tRNA dihydrouridine(20/20a) synthase DusA	NA	NA	NA	NA
WP_000891404.1\|369022_369265_+	envelope stress response protein PspG	NA	NA	NA	NA
WP_000235522.1\|369430_370414_-	quinone oxidoreductase	NA	NA	NA	NA
WP_000918366.1\|370496_371912_+	replicative DNA helicase DnaB	O80281	Escherichia_phage	8.3e-200	78.1
376057:376072	attR	NA	NA	NA	NA

DBSCAN-SWA_2

508792 : 567820

Pectobacterium_phage(11.11%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000312488.1\|508792_510052_+\|protease	FtsH protease activity modulator HflK	A0A1L2CVV0	Pectobacterium_phage	3.6e-05	25.5
WP_001232412.1\|510054_511059_+\|protease	protease modulator HflC	NA	NA	NA	NA
WP_001089295.1\|511140_511338_+	DUF2065 domain-containing protein	NA	NA	NA	NA
WP_000527955.1\|511441_512740_+	adenylosuccinate synthase	W5S5V7	Pithovirus	2.2e-66	35.9
WP_001177639.1\|512944_513370_+	nitric oxide-sensing transcriptional repressor NsrR	NA	NA	NA	NA
WP_000076303.1\|513408_515850_+	ribonuclease R	Q0GXV6	Lactococcus_phage	2.4e-66	32.9
WP_001293282.1\|516030_516762_+	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	NA	NA	NA	NA
WP_000220128.1\|516888_517290_+	DUF2170 family protein	NA	NA	NA	NA
WP_000511966.1\|517308_518007_+	PspA/IM30 family protein	NA	NA	NA	NA
WP_000012572.1\|518057_518717_+	YjfK family protein	NA	NA	NA	NA
WP_000547760.1\|518734_519133_+	DUF350 domain-containing protein	NA	NA	NA	NA
WP_000101670.1\|519142_519781_+	DUF1190 domain-containing protein	NA	NA	NA	NA
WP_000943960.1\|519783_520947_+	glutathionylspermidine synthase family protein	B2ZXR7	Ralstonia_phage	8.3e-81	43.8
WP_001301849.1\|521030_522656_+	isovaleryl-CoA dehydrogenase	NA	NA	NA	NA
WP_000811566.1\|522772_523048_-\|protease	protease activator YjfN	NA	NA	NA	NA
WP_000254636.1\|523196_523526_-	biofilm peroxide resistance protein BsmA	NA	NA	NA	NA
WP_153038067.1\|523707_524457_+	esterase	NA	NA	NA	NA
WP_000133631.1\|524453_525209_-	HTH-type transcriptional regulator UlaR	NA	NA	NA	NA
WP_001301921.1\|526735_528133_+	PTS ascorbate transporter subunit IIC	NA	NA	NA	NA
WP_000218362.1\|528148_528454_+	PTS ascorbate transporter subunit IIB	NA	NA	NA	NA
WP_000776517.1\|528463_528928_+	PTS ascorbate transporter subunit IIA	NA	NA	NA	NA
WP_000056760.1\|528941_529592_+	3-keto-L-gulonate-6-phosphate decarboxylase UlaD	NA	NA	NA	NA
WP_000949511.1\|529601_530456_+	L-ribulose-5-phosphate 3-epimerase UlaE	NA	NA	NA	NA
WP_001170812.1\|530455_531142_+	L-ribulose-5-phosphate 4-epimerase UlaF	NA	NA	NA	NA
WP_000492914.1\|531270_531546_-	DUF1471 domain-containing protein	NA	NA	NA	NA
WP_001216676.1\|531872_532268_+	30S ribosomal protein S6	NA	NA	NA	NA
WP_001296681.1\|532274_532589_+	primosomal replication protein N	NA	NA	NA	NA
WP_000135199.1\|532593_532821_+	30S ribosomal protein S18	NA	NA	NA	NA
WP_001196062.1\|532862_533312_+	50S ribosomal protein L9	NA	NA	NA	NA
WP_001301745.1\|533382_534177_-	DUF2686 family protein	NA	NA	NA	NA
WP_000604943.1\|534799_535231_-\|transposase	IS200/IS605-like element IS609 family transposase	A0A1S5RHE3	Helicobacter_phage	5.7e-43	59.9
WP_000826431.1\|535238_536447_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A077SL42	Escherichia_phage	5.4e-208	93.0
WP_001119481.1\|536581_537220_-	cell division protein YtfB	NA	NA	NA	NA
WP_000211225.1\|537437_538058_+	FKBP-type peptidyl-prolyl cis-trans isomerase	NA	NA	NA	NA
WP_000228346.1\|538366_539779_+	D-serine/D-alanine/glycine transporter	NA	NA	NA	NA
WP_000331454.1\|539823_540486_-	iron-sulfur cluster repair protein YtfE	NA	NA	NA	NA
WP_001301505.1\|540593_541559_-	DMT family transporter	NA	NA	NA	NA
WP_000560631.1\|541666_542527_-	NAD(P)H:quinone oxidoreductase	NA	NA	NA	NA
WP_001302935.1\|542615_542996_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000589488.1\|543113_545057_-	2',3'-cyclic-nucleotide 2'-phosphodiesterase	NA	NA	NA	NA
WP_000886884.1\|545246_545987_+	3'(2'),5'-bisphosphate nucleotidase CysQ	NA	NA	NA	NA
WP_000937658.1\|546198_547137_+	hypothetical protein	NA	NA	NA	NA
WP_000175296.1\|547199_547754_-	YtfJ family protein	NA	NA	NA	NA
WP_000689228.1\|548078_548285_+	DUF1107 domain-containing protein	NA	NA	NA	NA
WP_000935036.1\|548380_549724_-	HlyC/CorC family transporter	NA	NA	NA	NA
WP_001301936.1\|550046_550685_-	peptide-methionine (S)-S-oxide reductase MsrA	NA	NA	NA	NA
WP_001269327.1\|550890_552624_+	autotransporter assembly complex protein TamA	NA	NA	NA	NA
WP_000060930.1\|552620_556400_+	autotransporter assembly complex protein TamB	NA	NA	NA	NA
WP_001219160.1\|556402_556744_+	gamma-glutamylcyclotransferase	NA	NA	NA	NA
WP_001223210.1\|556955_557207_+	type II toxin-antitoxin system ChpS family antitoxin	NA	NA	NA	NA
WP_000239579.1\|557200_557551_+	endoribonuclease toxin ChpB	NA	NA	NA	NA
WP_000055075.1\|557630_558161_-	inorganic diphosphatase	A0A2H4J8U1	uncultured_Caudovirales_phage	1.2e-55	63.3
WP_000265942.1\|558470_559427_+	galactofuranose ABC transporter substrate-binding protein YtfQ	NA	NA	NA	NA
WP_000205805.1\|559566_561069_+	sugar ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	1.8e-11	30.3
WP_001301928.1\|561082_562105_+	ABC transporter permease	NA	NA	NA	NA
WP_000596020.1\|562091_563087_+	sugar ABC transporter permease YjfF	NA	NA	NA	NA
WP_000853749.1\|563119_564118_-	class 1 fructose-bisphosphatase	A0A1V0SKX4	Klosneuvirus	2.1e-69	42.6
WP_001219792.1\|564293_565667_+	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase	NA	NA	NA	NA
WP_000166270.1\|565822_566374_-	ribosome-associated protein	NA	NA	NA	NA
WP_001162171.1\|566467_567820_+\|protease	metalloprotease PmbA	NA	NA	NA	NA

DBSCAN-SWA_3

600240 : 612816

Enterobacteria_phage(81.82%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000772662.1\|600240_601515_+	DUF4102 domain-containing protein	B7SYF8	Stenotrophomonas_phage	4.1e-73	41.0
WP_000936844.1\|601682_601988_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_001453880.1\|602064_602799_+	type II restriction endonuclease	NA	NA	NA	NA
WP_000095622.1\|602836_604081_-	DNA cytosine methyltransferase	F2Y148	Organic_Lake_phycodnavirus	9.3e-46	31.1
WP_000446132.1\|604406_604979_-	Polarity suppression protein	Q7M2A1	Enterobacteria_phage	2.2e-95	97.3
WP_000638634.1\|605052_605553_-	transactivation protein	NA	NA	NA	NA
WP_001283021.1\|605549_606284_-	hypothetical protein	Q7M2A2	Enterobacteria_phage	2.3e-129	98.8
WP_001149160.1\|606835_607102_+	AlpA family transcriptional regulator	Q7M299	Enterobacteria_phage	4.9e-45	100.0
WP_000980224.1\|607098_607689_+	host cell division inhibitor Icd-like protein	Q7M2A7	Enterobacteria_phage	5.3e-60	90.3
WP_001244670.1\|607681_607969_+	hypothetical protein	Q7M2A0	Enterobacteria_phage	2.5e-47	96.8
WP_000459287.1\|607961_608417_+	hypothetical protein	Q7M298	Enterobacteria_phage	4.7e-64	98.2
WP_000856729.1\|608552_608873_+	hypothetical protein	NA	NA	NA	NA
WP_000783684.1\|608887_611221_+	DNA primase	Q7M2A8	Enterobacteria_phage	0.0e+00	99.1
WP_044815386.1\|611576_611771_+	hypothetical protein	Q38404	Enterobacteria_phage	1.5e-24	100.0
WP_001301682.1\|611988_612816_+	DUF4102 domain-containing protein	Q7M297	Enterobacteria_phage	4.3e-55	40.4

DBSCAN-SWA_4

1007579 : 1089597

Shigella_phage(46.55%)

integrase,holin,terminase,plate,head,capsid,lysis,transposase,tail,portal,protease

attL 1024827:1024841|attR 1090013:1090027

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000246433.1\|1007579_1008911_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_001080153.1\|1008913_1009438_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_001113707.1\|1009434_1010715_-	type VI secretion system-associated FHA domain protein TagH	NA	NA	NA	NA
WP_000348794.1\|1010739_1011822_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_000393844.1\|1011785_1013636_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_000599596.1\|1013639_1014053_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_000056994.1\|1014143_1015535_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_000123970.1\|1015585_1015810_-	hypothetical protein	NA	NA	NA	NA
WP_000037399.1\|1015844_1016345_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_001142958.1\|1017041_1017560_+	Hcp family type VI secretion system effector	NA	NA	NA	NA
WP_000103335.1\|1017769_1019911_+	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	1.4e-25	25.0
WP_000509142.1\|1019986_1024210_+	RHS repeat protein	A0A2H4JHK7	uncultured_Caudovirales_phage	2.4e-21	42.3
WP_000247943.1\|1024411_1024675_+	hypothetical protein	NA	NA	NA	NA
WP_120795385.1\|1024589_1024775_-	protein YncO	NA	NA	NA	NA
1024827:1024841	attL	NA	NA	NA	NA
WP_000027427.1\|1024855_1026028_+\|transposase	ISAs1-like element ISEc26 family transposase	NA	NA	NA	NA
WP_001118031.1\|1026145_1026916_-	2-oxoglutaramate amidase	NA	NA	NA	NA
WP_000532698.1\|1027069_1027543_+	C-lysozyme inhibitor	NA	NA	NA	NA
WP_000973071.1\|1027585_1030030_-	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_000284050.1\|1030269_1030848_+	D-sedoheptulose 7-phosphate isomerase	A0A067XQR2	Caulobacter_phage	1.1e-14	32.0
WP_001301698.1\|1030952_1031720_+	class II glutamine amidotransferase	NA	NA	NA	NA
WP_001225679.1\|1031690_1032431_-	murein L,D-transpeptidase	NA	NA	NA	NA
WP_001303998.1\|1032586_1032847_-	type II toxin-antitoxin system mRNA interferase toxin YafQ	NA	NA	NA	NA
WP_000729705.1\|1032865_1033126_-	type II toxin-antitoxin system antitoxin DinJ	NA	NA	NA	NA
WP_000543891.1\|1033311_1034085_+	NlpC/P60 family protein	A0A1V0DZX6	Clostridioides_phage	1.2e-19	37.7
WP_001301901.1\|1034902_1036642_-	flagellar type III secretion system protein FlhA	NA	NA	NA	NA
WP_001301640.1\|1036601_1037372_+	putative lateral flagellar export/assembly protein LafU	NA	NA	NA	NA
WP_001226186.1\|1037442_1038498_+	DNA polymerase IV	NA	NA	NA	NA
WP_000554757.1\|1038549_1038843_+	type I toxin-antitoxin system antitoxin YafN	NA	NA	NA	NA
WP_001263495.1\|1038845_1039244_+	type II toxin-antitoxin system YafO family toxin	NA	NA	NA	NA
WP_001059871.1\|1039253_1039706_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_001303804.1\|1040012_1040279_+	hypothetical protein	NA	NA	NA	NA
WP_077626217.1\|1040211_1040748_+	peptide chain release factor H	NA	NA	NA	NA
WP_001293009.1\|1040804_1042262_-	cytosol nonspecific dipeptidase	NA	NA	NA	NA
WP_001291990.1\|1042522_1042981_+	xanthine phosphoribosyltransferase	NA	NA	NA	NA
WP_000189536.1\|1043072_1044317_+	esterase FrsA	NA	NA	NA	NA
WP_000174701.1\|1044374_1044776_+	sigma factor-binding protein Crl	NA	NA	NA	NA
WP_000749881.1\|1044814_1045870_-	phosphoporin PhoE	Q1MVN1	Enterobacteria_phage	7.7e-118	60.9
WP_001285288.1\|1046157_1047261_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.1e-61	40.4
WP_000893282.1\|1047272_1048526_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	3.4e-96	47.2
WP_000051887.1\|1048730_1049894_-\|integrase	site-specific integrase	U5P434	Shigella_phage	2.4e-229	100.0
WP_077769569.1\|1049770_1050205_-	helix-turn-helix domain-containing protein	U5P4J3	Shigella_phage	1.0e-76	98.6
WP_000206732.1\|1050120_1050426_-	hypothetical protein	U5P0J0	Shigella_phage	6.8e-51	100.0
WP_001242749.1\|1050425_1050788_-	phage protein	U5P092	Shigella_phage	2.1e-67	100.0
WP_000008235.1\|1050778_1051315_-	5'-deoxynucleotidase	S5MW55	Escherichia_phage	8.2e-100	98.9
WP_000917896.1\|1051991_1052288_-	hypothetical protein	Q8SBF7	Shigella_phage	1.2e-52	100.0
WP_001020634.1\|1052565_1053258_-	helix-turn-helix transcriptional regulator	S5FUZ3	Shigella_phage	1.0e-126	100.0
WP_001191674.1\|1053355_1053616_+	helix-turn-helix transcriptional regulator	S5FKP1	Shigella_phage	7.1e-41	100.0
WP_000515845.1\|1053608_1054160_+	protein YmfL	S5FXP0	Shigella_phage	3.4e-101	99.5
WP_001250269.1\|1054335_1054515_+	DUF4222 domain-containing protein	S5M7S5	Escherichia_phage	7.8e-15	68.5
WP_000104949.1\|1054504_1055446_+	helix-turn-helix domain-containing protein	S5FM81	Shigella_phage	3.3e-144	99.7
WP_072141203.1\|1055442_1055937_+	PerC family transcriptional regulator	A0A0P0ZCF0	Stx2-converting_phage	1.6e-86	98.1
WP_001303054.1\|1055936_1056590_+	phage N-6-adenine-methyltransferase	A5LH72	Enterobacteria_phage	2.1e-126	99.1
WP_000210141.1\|1056586_1056913_+	LexA family transcriptional regulator	A0A291AWY9	Escherichia_phage	3.9e-52	97.2
WP_000767113.1\|1056909_1057299_+	RusA family crossover junction endodeoxyribonuclease	A0A0P0ZD39	Stx2-converting_phage	7.1e-69	100.0
WP_001061444.1\|1057318_1058128_+	KilA-N domain-containing protein	A0A291AWU7	Escherichia_phage	1.8e-151	100.0
WP_001360050.1\|1058135_1059125_+	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	1.5e-195	100.0
WP_001008431.1\|1059138_1059891_+	antitermination protein	Q8SBE4	Shigella_phage	1.7e-135	98.0
WP_000484663.1\|1060106_1060646_+	hypothetical protein	NA	NA	NA	NA
WP_001310393.1\|1060789_1061023_+	hypothetical protein	NA	NA	NA	NA
WP_001449601.1\|1061301_1061595_+	site-specific DNA-methyltransferase	Q8SBE2	Shigella_phage	1.5e-42	90.7
WP_001120501.1\|1061731_1062067_+\|holin	phage holin, lambda family	Q8SBE1	Shigella_phage	2.0e-59	99.1
WP_001197766.1\|1062070_1062547_+	glycoside hydrolase family protein	K7PKV2	Enterobacteria_phage	3.0e-85	96.2
WP_001228695.1\|1062763_1062946_+\|lysis	prophage lysis lipoprotein RzoD	K7PHU6	Enterobacteria_phage	2.9e-17	98.3
WP_000738423.1\|1063036_1063330_-	increased serum survival lipoprotein Iss	K7PL54	Enterobacteria_phage	2.0e-44	91.8
WP_085948178.1\|1064028_1065242_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_000929175.1\|1065644_1066139_+\|terminase	phage terminase small subunit P27 family	U5P067	Shigella_phage	3.9e-88	99.4
WP_128484532.1\|1066372_1067869_+\|terminase	terminase large subunit	A0A1C9IIA1	Salmonella_phage	5.3e-290	98.8
WP_000923141.1\|1068016_1069243_+\|portal	phage portal protein	Q8SBI0	Shigella_phage	4.1e-240	98.8
WP_000999805.1\|1069235_1069838_+\|head,protease	HK97 family phage prohead protease	Q8SBH9	Shigella_phage	6.8e-111	100.0
WP_000766100.1\|1069848_1071078_+\|capsid	phage major capsid protein	Q8SBH8	Shigella_phage	7.6e-226	99.3
WP_000924828.1\|1071156_1071480_+\|head,tail	phage gp6-like head-tail connector protein	Q8SBH7	Shigella_phage	3.5e-53	100.0
WP_000702395.1\|1071476_1071887_+\|head	phage head closure protein	M1FJ87	Enterobacteria_phage	5.7e-69	93.4
WP_000224836.1\|1071861_1072368_+	hypothetical protein	Q8SBH5	Shigella_phage	2.9e-83	92.9
WP_000779288.1\|1072364_1072925_+	hypothetical protein	M1FQV7	Enterobacteria_phage	6.8e-105	99.5
WP_000497751.1\|1072933_1073104_+	DUF2635 domain-containing protein	Q8SBH3	Shigella_phage	9.3e-26	100.0
WP_000155728.1\|1073087_1074584_+\|tail	tail sheath protein	M1FN90	Enterobacteria_phage	1.1e-271	98.8
WP_000090993.1\|1074583_1074940_+	hypothetical protein	U5P076	Shigella_phage	1.2e-62	99.2
WP_000661054.1\|1074939_1075209_+\|tail	phage tail assembly protein	M1FPE4	Enterobacteria_phage	3.5e-43	100.0
WP_000807197.1\|1075350_1077186_+\|tail	phage tail tape measure protein	Q8SBG9	Shigella_phage	1.5e-307	99.7
WP_000219910.1\|1077246_1078575_+	DNA circularization protein	Q8SBG8	Shigella_phage	2.5e-246	98.9
WP_000999513.1\|1078571_1079651_+\|plate	baseplate protein	U5P0H6	Shigella_phage	9.1e-207	99.7
WP_001259066.1\|1079650_1080199_+\|plate	phage baseplate assembly protein V	U5P081	Shigella_phage	3.6e-95	97.8
WP_000424732.1\|1080198_1080624_+	hypothetical protein	U5P0R9	Shigella_phage	2.3e-81	100.0
WP_000785302.1\|1080610_1081669_+\|plate	baseplate J/gp47 family protein	Q8SBG4	Shigella_phage	1.6e-200	98.9
WP_000383550.1\|1081659_1082244_+	YmfQ family protein	O22003	Shigella_phage	7.8e-112	98.5
WP_032195359.1\|1082514_1082910_+	hypothetical protein	A0A0F7LBW5	Escherichia_phage	4.8e-65	96.9
WP_001008234.1\|1082930_1083374_+\|tail	tail fiber assembly protein	A0A0F7LDZ0	Escherichia_phage	2.2e-82	100.0
WP_000368084.1\|1083345_1083948_-\|tail	tail fiber assembly protein	M1SV83	Escherichia_phage	1.2e-99	90.5
WP_001145352.1\|1083947_1084466_-\|tail	tail fiber protein	A0A0F7LCR3	Escherichia_phage	1.2e-55	62.0
WP_000905124.1\|1084496_1085051_+	site-specific DNA recombinase	A0A0F7LA37	Escherichia_phage	2.8e-87	87.8
WP_000355484.1\|1085111_1085885_-	hypothetical protein	G9IA57	Pseudomonas_phage	2.4e-36	38.5
WP_000246059.1\|1086709_1087453_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_001130487.1\|1088415_1089597_+\|integrase	tyrosine-type recombinase/integrase	Q7M297	Enterobacteria_phage	2.4e-144	61.3
1090013:1090027	attR	NA	NA	NA	NA

DBSCAN-SWA_5

1668563 : 1706658

Enterobacteria_phage(51.22%)

integrase,holin,terminase,lysis,tail,portal,protease

attL 1658005:1658019|attR 1690294:1690308

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1658005:1658019	attL	NA	NA	NA	NA
WP_024219169.1\|1668563_1669445_-\|integrase	tyrosine-type recombinase/integrase	K7P6P6	Enterobacteria_phage	7.2e-162	99.7
WP_001303849.1\|1669607_1669826_-	excisionase	Q77WA4	Escherichia_phage	3.7e-35	100.0
WP_000545728.1\|1669865_1670033_-	hypothetical protein	A0A0K2FJ46	Enterobacteria_phage	1.3e-27	98.2
WP_000120056.1\|1670275_1670878_+	hypothetical protein	NA	NA	NA	NA
WP_000763363.1\|1671088_1671310_-	TraR/DksA family transcriptional regulator	A0A0N7C211	Escherichia_phage	6.4e-35	98.6
WP_023436627.1\|1671408_1671690_-	hypothetical protein	A0A0P0ZE02	Stx2-converting_phage	1.6e-46	97.8
WP_000548536.1\|1671700_1671892_-	DUF1382 family protein	A0A0P0ZC67	Stx2-converting_phage	1.1e-25	96.8
WP_000682316.1\|1671864_1672047_-	DUF1317 domain-containing protein	A0A0P0ZAS9	Stx2-converting_phage	4.1e-27	95.0
WP_000186844.1\|1672043_1672724_-	YqaJ viral recombinase family protein	A0A0P0ZCD4	Stx2-converting_phage	3.5e-132	99.6
WP_001254218.1\|1673421_1673604_+	NinE family protein	Q8H9Z6	Enterobacteria_phage	4.8e-28	96.7
WP_000567001.1\|1673600_1673771_+	protein ninF	Q716C4	Shigella_phage	7.9e-25	96.4
WP_001108055.1\|1673763_1674384_+	recombination protein NinG	Q716C3	Shigella_phage	1.6e-94	96.1
WP_001028857.1\|1674380_1675046_+	serine/threonine protein phosphatase	Q5TJL8	Enterobacteria_phage	9.4e-130	99.1
WP_000750155.1\|1675257_1676217_-	lipid A deacylase LpxR family protein	NA	NA	NA	NA
WP_032160865.1\|1676554_1676677_+	YlcG family protein	NA	NA	NA	NA
WP_001097238.1\|1676691_1677381_+	Q antiterminator encoded by prophage CP-933P	I6PDF8	Cronobacter_phage	1.5e-58	48.1
WP_001302581.1\|1677564_1678308_+	hypothetical protein	NA	NA	NA	NA
WP_000499454.1\|1678393_1678552_+	DUF3927 domain-containing protein	NA	NA	NA	NA
WP_012578864.1\|1678632_1679031_-	hypothetical protein	H6WZJ8	Escherichia_phage	6.9e-11	83.3
WP_000284524.1\|1679173_1679389_+\|holin	holin	A0A0P0ZC45	Stx2-converting_phage	4.5e-33	98.6
WP_000075107.1\|1679388_1679886_+	lysozyme	A0A1B5FP97	Escherichia_phage	7.1e-90	98.2
WP_000092302.1\|1679882_1680350_+\|lysis	lysis protein	A0A291AWW3	Escherichia_phage	9.4e-76	97.4
WP_001139679.1\|1680337_1680490_+	hypothetical protein	K7PKL2	Enterobacteria_phage	8.9e-20	96.0
WP_000934137.1\|1681654_1683757_+\|terminase	phage terminase large subunit family protein	A0A291AWY5	Escherichia_phage	0.0e+00	96.7
WP_001072975.1\|1683753_1683966_+	hypothetical protein	A5LH28	Enterobacteria_phage	1.1e-31	100.0
WP_010904538.1\|1683893_1685018_+\|portal	phage portal protein	K7PJP3	Enterobacteria_phage	5.4e-194	99.4
WP_127446149.1\|1685139_1685475_+\|portal	phage portal protein	A5LH29	Enterobacteria_phage	9.1e-57	99.1
WP_001136598.1\|1685419_1687447_+\|protease	Clp protease ClpP	K7PGT6	Enterobacteria_phage	0.0e+00	99.2
WP_001097050.1\|1687533_1687857_+	DUF2190 family protein	A0A291AWX2	Escherichia_phage	8.5e-52	100.0
WP_001283153.1\|1687849_1688125_+	DNA breaking-rejoining protein	K7PH43	Enterobacteria_phage	2.3e-45	100.0
WP_000677094.1\|1688136_1688715_+\|tail	phage tail protein	A5LH33	Enterobacteria_phage	6.1e-101	99.0
WP_001079422.1\|1688711_1689113_+\|tail	tail protein	A5LH34	Enterobacteria_phage	2.0e-71	98.5
WP_000211123.1\|1689123_1689867_+\|tail	phage tail protein	A5LH35	Enterobacteria_phage	9.5e-131	98.0
WP_153038097.1\|1689927_1690314_+\|tail	phage minor tail protein G	A0A291AWW5	Escherichia_phage	3.6e-65	99.2
1690294:1690308	attR	NA	NA	NA	NA
WP_001161009.1\|1690322_1690652_+\|tail	phage tail assembly protein T	A5LH37	Enterobacteria_phage	7.6e-56	100.0
WP_000371994.1\|1690623_1693689_+\|tail	phage tail tape measure protein	A0A291AWX1	Escherichia_phage	0.0e+00	98.9
WP_000447253.1\|1693688_1694018_+\|tail	phage tail protein	A5LH39	Enterobacteria_phage	1.7e-60	100.0
WP_001152360.1\|1694027_1694726_+\|tail	phage minor tail protein L	A5LH40	Enterobacteria_phage	3.9e-134	99.1
WP_000194779.1\|1694731_1695475_+\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	2.0e-149	97.6
WP_001508920.1\|1695411_1696020_+\|tail	tail assembly protein	A5LH42	Enterobacteria_phage	7.1e-100	93.6
WP_001233141.1\|1699564_1700164_+	outer membrane protein	H6WZM8	Escherichia_phage	1.8e-103	92.5
WP_000741874.1\|1700223_1701540_+\|tail	tail fiber protein	Q6H9S9	Enterobacteria_phage	2.0e-67	95.6
WP_001024022.1\|1701541_1701811_+\|tail	phage tail protein	A0A1I9LJT0	Stx_converting_phage	4.9e-45	98.9
WP_000950813.1\|1701987_1702968_+	type III secretion system effector arginine glycosyltransferase NleB2	Q8HAB2	Salmonella_phage	2.9e-87	49.5
WP_115801843.1\|1703001_1704021_+\|protease	type III secretion system effector zinc metalloprotease NleC	NA	NA	NA	NA
WP_072127173.1\|1704517_1704679_+\|tail	phage tail protein	K7PMH7	Enterobacteria_phage	3.9e-13	72.5
WP_000951026.1\|1704847_1705729_+	type III secretion system effector kinase NleH1-1	A5LH48	Enterobacteria_phage	8.6e-147	90.1
WP_001247925.1\|1705959_1706658_+\|protease	T3SS effector zinc metalloprotease NleD	NA	NA	NA	NA

DBSCAN-SWA_6

1923366 : 1992931

Escherichia_phage(26.67%)

integrase,holin,head,transposase,portal,tail,protease

attL 1931854:1931869|attR 1953220:1953235

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000156526.1\|1923366_1925127_-\|protease	Lon protease family protein	NA	NA	NA	NA
WP_000877161.1\|1925312_1925765_+	macrodomain Ter protein MatP	NA	NA	NA	NA
WP_000750416.1\|1925840_1926881_-	porin OmpA	NA	NA	NA	NA
WP_000288710.1\|1927237_1927747_-	cell division inhibitor SulA	NA	NA	NA	NA
WP_000839159.1\|1927965_1928595_+	CRP-S regulon transcriptional coactivator Sxy	NA	NA	NA	NA
WP_000875023.1\|1928557_1930720_-	TIGR01666 family membrane protein	NA	NA	NA	NA
WP_001261230.1\|1930729_1931176_-	YccF domain-containing protein	NA	NA	NA	NA
WP_001301436.1\|1931298_1933353_+	DNA helicase IV	A7KV33	Bacillus_phage	5.9e-21	27.9
1931854:1931869	attL	NA	NA	NA	NA
WP_000424181.1\|1933384_1933843_-	methylglyoxal synthase	NA	NA	NA	NA
WP_000847791.1\|1933938_1934601_-	DUF2057 family protein	NA	NA	NA	NA
WP_000665217.1\|1934773_1935187_+	CoA-binding protein	NA	NA	NA	NA
WP_001295356.1\|1935231_1935549_-	heat shock protein HspQ	NA	NA	NA	NA
WP_000116288.1\|1935606_1936797_-	23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI	NA	NA	NA	NA
WP_000048252.1\|1936891_1937170_+	acylphosphatase	NA	NA	NA	NA
WP_000904442.1\|1937166_1937496_-	sulfurtransferase TusE	NA	NA	NA	NA
WP_000375128.1\|1937586_1938246_-\|protease	FtsH protease modulator YccA	A0A2H4JFM9	uncultured_Caudovirales_phage	1.8e-48	55.3
WP_001299351.1\|1938653_1939673_-\|integrase	tyrosine-type recombinase/integrase	A0A192Y7M7	Salmonella_phage	1.3e-85	49.7
WP_000273151.1\|1939650_1939893_-	DUF4224 domain-containing protein	NA	NA	NA	NA
WP_000034474.1\|1939960_1942432_-	exonuclease	A0A192Y6E0	Salmonella_phage	8.8e-56	56.6
WP_001098307.1\|1942525_1942717_-	DUF1482 family protein	NA	NA	NA	NA
WP_000413705.1\|1942713_1942902_-	cell division inhibition protein DicB	NA	NA	NA	NA
WP_001133046.1\|1943475_1943661_+	hypothetical protein	NA	NA	NA	NA
WP_000394511.1\|1943847_1944237_-	hypothetical protein	NA	NA	NA	NA
WP_000379575.1\|1944378_1944534_-	DUF1391 domain-containing protein	M4QQ57	Salicola_phage	3.0e-07	53.2
WP_001303876.1\|1944811_1945099_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_000536233.1\|1945098_1945290_-	hypothetical protein	NA	NA	NA	NA
WP_000986592.1\|1945317_1945719_-	helix-turn-helix domain-containing protein	A0A1B5FPF4	Escherichia_phage	7.4e-13	54.5
WP_000887453.1\|1945827_1946100_+	hypothetical protein	A0A0U2S629	Escherichia_phage	1.1e-12	45.8
WP_000693855.1\|1946083_1946509_+	Rha family transcriptional regulator	NA	NA	NA	NA
WP_000273724.1\|1946715_1947171_-	hypothetical protein	NA	NA	NA	NA
WP_001205823.1\|1947249_1948341_+	hypothetical protein	V5URT9	Shigella_phage	5.1e-133	70.0
WP_000788751.1\|1948347_1949094_+	replication protein	A0A088CBP4	Shigella_phage	6.2e-114	84.2
WP_000450992.1\|1949115_1949886_+	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	6.1e-80	64.5
WP_001151233.1\|1949901_1950315_+	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	9.8e-61	89.1
WP_000160654.1\|1950666_1951440_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_000955173.1\|1951805_1951943_-	hypothetical protein	Q7Y2Q9	Escherichia_phage	5.4e-08	96.6
WP_001013642.1\|1951987_1952200_+	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	1.5e-25	95.4
WP_001341388.1\|1952367_1952646_+	hypothetical protein	I6PCV7	Cronobacter_phage	5.7e-12	48.4
WP_001265172.1\|1952647_1953697_+	DUF968 domain-containing protein	U5P0K4	Shigella_phage	1.2e-110	54.9
1953220:1953235	attR	NA	NA	NA	NA
WP_001217436.1\|1953709_1954081_+	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	1.3e-35	63.7
WP_000090264.1\|1954070_1954442_+	antitermination protein	Q777W5	Enterobacteria_phage	4.0e-53	83.2
WP_000265265.1\|1954593_1955412_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_001303877.1\|1955698_1955938_+	hypothetical protein	Q9MC00	Enterobacteria_phage	7.7e-18	98.0
WP_000261909.1\|1956032_1956746_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_000874392.1\|1957512_1959363_+	SASA family carbohydrate esterase	B6DZ89	Enterobacteria_phage	0.0e+00	96.1
WP_085948178.1\|1959538_1960751_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_001303878.1\|1960956_1961271_-	PerC family transcriptional regulator	NA	NA	NA	NA
WP_012816791.1\|1961798_1961984_-	membrane protein	A0A0P0ZCT3	Stx2-converting_phage	1.2e-18	100.0
WP_000675931.1\|1962205_1962319_-	hypothetical protein	A0A2L1IV24	Escherichia_phage	6.6e-12	100.0
WP_001003118.1\|1962539_1963073_-	lysozyme	A0A1U9AJ98	Stx1_converting_phage	3.1e-99	94.4
WP_000138558.1\|1963232_1963505_+	hypothetical protein	NA	NA	NA	NA
WP_000411791.1\|1963760_1963967_-\|holin	holin	Q6H9V8	Enterobacteria_phage	4.5e-30	97.1
WP_000235421.1\|1964717_1964993_+	hypothetical protein	A0A1I9KFT4	Aeromonas_phage	2.4e-10	51.5
WP_001171554.1\|1965068_1965449_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZBP6	Stx2-converting_phage	1.4e-66	100.0
WP_000612591.1\|1965445_1965793_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	2.2e-61	100.0
WP_000998048.1\|1965842_1967381_+\|transposase	IS66-like element ISEc8 family transposase	A0A0P0ZBS5	Stx2-converting_phage	1.5e-300	100.0
WP_001301919.1\|1967430_1967673_+	DNA packaging protein	NA	NA	NA	NA
WP_000259002.1\|1969557_1969764_+\|head,tail	head-tail joining protein	K7PM10	Enterobacteria_phage	7.9e-11	56.9
WP_000831796.1\|1969760_1971353_+\|portal	phage portal protein	K7P6U7	Enterobacteria_phage	8.7e-182	60.5
WP_001254002.1\|1971342_1972848_+	S49 family peptidase	A0A2I6TC87	Escherichia_phage	1.2e-100	54.2
WP_000256723.1\|1972884_1973232_+\|head	head decoration protein	C6ZCY1	Enterobacteria_phage	2.6e-22	58.1
WP_001301534.1\|1973289_1973556_+	hypothetical protein	NA	NA	NA	NA
WP_029208397.1\|1973537_1974278_+\|tail	phage tail protein	Q687F6	Enterobacteria_phage	3.6e-130	98.0
WP_000479117.1\|1974291_1974723_+\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	2.4e-41	68.1
WP_000533402.1\|1974749_1975163_+\|tail	phage tail assembly protein T	S5MDP5	Escherichia_phage	1.6e-42	82.2
WP_000082473.1\|1975143_1977723_+\|tail	phage tail tape measure protein	A0A2R9YJM8	Escherichia_phage	0.0e+00	79.9
WP_000847298.1\|1977719_1978049_+\|tail	phage tail protein	Q687F2	Enterobacteria_phage	4.3e-59	100.0
WP_001302968.1\|1978048_1978747_+\|tail	phage minor tail protein L	A0A0P0ZBE3	Stx2-converting_phage	2.9e-129	97.8
WP_001371725.1\|1978757_1979501_+\|tail	phage tail protein	Q6H9T4	Enterobacteria_phage	8.6e-148	97.6
WP_050546863.1\|1979446_1980079_+\|tail	tail assembly protein	A0A0P0ZC16	Stx2-converting_phage	5.8e-105	99.5
WP_000649827.1\|1980269_1980797_-	superoxide dismutase family protein	Q9MC02	Salmonella_phage	4.8e-52	55.8
WP_000515109.1\|1980930_1984404_+	host specificity protein J	A0A0P0ZCI5	Stx2-converting_phage	0.0e+00	96.2
WP_001230444.1\|1984471_1985071_+	outer membrane protein	A0A0P0ZCF6	Stx2-converting_phage	8.8e-111	99.0
WP_000268855.1\|1985135_1986449_+\|tail	tail fiber protein	A0A0P0ZE15	Stx2-converting_phage	2.0e-83	99.1
WP_001023407.1\|1986450_1986720_+\|tail	phage tail protein	H6WZN0	Escherichia_phage	1.4e-44	98.9
WP_001301613.1\|1988712_1989831_+	hydrogenase 1 small subunit	NA	NA	NA	NA
WP_000107391.1\|1989827_1991621_+	Ni/Fe-hydrogenase large subunit	NA	NA	NA	NA
WP_001186424.1\|1991639_1992347_+	Ni/Fe-hydrogenase b-type cytochrome subunit	NA	NA	NA	NA
WP_000003653.1\|1992343_1992931_+\|protease	hydrogenase 1 maturation protease	NA	NA	NA	NA

DBSCAN-SWA_7

2243915 : 2364465

155

Enterobacteria_phage(38.18%)

integrase,holin,terminase,head,capsid,tRNA,lysis,transposase,tail,portal,protease

attL 2309826:2309841|attR 2338080:2338095

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000952736.1\|2243915_2244737_+	NAD-dependent protein deacylase	A0A2I7S9Y2	Vibrio_phage	5.6e-23	35.6
WP_000759316.1\|2244892_2245939_-	spermidine/putrescine ABC transporter substrate-binding protein PotD	NA	NA	NA	NA
WP_000580316.1\|2245935_2246730_-	spermidine/putrescine ABC transporter permease PotC	NA	NA	NA	NA
WP_000074985.1\|2246896_2248015_-\|integrase	tyrosine-type recombinase/integrase	Q77Z04	Phage_21	1.0e-83	43.9
WP_000003742.1\|2247983_2248253_-	excisionase	NA	NA	NA	NA
WP_077699040.1\|2248314_2248704_-	3'-5' exoribonuclease	K7PLW7	Enterobacteria_phage	1.3e-38	60.0
WP_000559928.1\|2248836_2249352_+	hypothetical protein	NA	NA	NA	NA
WP_001414141.1\|2249466_2249619_-	DUF1391 domain-containing protein	M4QQ57	Salicola_phage	1.0e-07	55.3
WP_000948454.1\|2249934_2250411_-	hypothetical protein	A0A2D1GNH0	Pseudomonas_phage	5.7e-12	53.4
WP_000711018.1\|2250535_2250859_+	transcriptional regulator	A0A0R6PH31	Moraxella_phage	6.2e-10	44.9
WP_000693962.1\|2250842_2251268_+	Rha family transcriptional regulator	NA	NA	NA	NA
WP_001262323.1\|2251336_2252374_+	hypothetical protein	A0A0U2RT81	Escherichia_phage	3.3e-89	79.5
WP_001301518.1\|2252405_2252828_+	hypothetical protein	A0A0U2JGJ0	Escherichia_phage	1.8e-73	91.4
WP_000451012.1\|2252861_2253578_+	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	2.1e-71	62.4
WP_000017339.1\|2253574_2253892_+	hypothetical protein	A0A222YXX1	Escherichia_phage	1.1e-32	70.6
WP_153038080.1\|2253888_2254191_+	DUF4406 domain-containing protein	A0A0U2SAZ1	Escherichia_phage	7.2e-45	86.9
WP_001017965.1\|2254180_2254498_+	DUF4752 family protein	A0A1I9LJV1	Stx_converting_phage	2.1e-42	92.4
WP_000156547.1\|2254451_2254769_+	hypothetical protein	A0A088CQ13	Enterobacteria_phage	4.4e-45	90.0
WP_000515959.1\|2254755_2255193_+	ead/Ea22-like family protein	Q8VNQ2	Enterobacteria_phage	1.9e-38	94.0
WP_001014296.1\|2255194_2255386_+	hypothetical protein	G9L660	Escherichia_phage	1.6e-26	98.4
WP_000207955.1\|2255388_2255976_+	DUF551 domain-containing protein	K7PH57	Enterobacteria_phage	7.5e-38	45.8
WP_001278450.1\|2256091_2256196_+	hypothetical protein	NA	NA	NA	NA
WP_000887477.1\|2256384_2256597_+	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	3.1e-18	68.6
WP_001341388.1\|2256764_2257043_+	hypothetical protein	I6PCV7	Cronobacter_phage	5.7e-12	48.4
WP_001265159.1\|2257044_2258094_+	DUF968 domain-containing protein	U5P0K4	Shigella_phage	1.4e-106	53.2
WP_001217410.1\|2258106_2258481_+	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	2.1e-33	62.7
WP_000762929.1\|2258477_2259299_+	antitermination protein	K7P7B9	Enterobacteria_phage	1.3e-83	58.6
WP_000216629.1\|2259895_2260063_+	DUF3927 domain-containing protein	H6WZJ7	Escherichia_phage	1.9e-10	72.5
WP_000023167.1\|2260377_2262315_+	SASA family carbohydrate esterase	Q6H9W1	Enterobacteria_phage	2.5e-292	76.8
WP_001213059.1\|2262462_2262645_+	DUF1378 family protein	A0A2R2Z345	Escherichia_phage	1.0e-14	67.8
WP_001289717.1\|2262682_2262952_+	DUF826 domain-containing protein	A0A2R2Z348	Escherichia_phage	8.2e-08	75.3
WP_000284518.1\|2263027_2263243_+\|holin	holin	Q6H9V8	Enterobacteria_phage	2.0e-33	100.0
WP_000731241.1\|2263247_2263592_+	YdfR family protein	A0A0P0ZD64	Stx2-converting_phage	1.7e-58	99.1
WP_000992148.1\|2263642_2264176_+	lysozyme	B6DZ92	Enterobacteria_phage	3.0e-102	99.4
WP_001056806.1\|2264446_2265016_+	hypothetical protein	A0A1I9LJR6	Stx_converting_phage	3.1e-105	100.0
WP_000539792.1\|2265015_2265162_+	hypothetical protein	A0A0P0ZE99	Stx2-converting_phage	2.6e-16	100.0
WP_001208682.1\|2265389_2265596_+	hypothetical protein	H6WRZ6	Salmonella_phage	7.1e-12	64.7
WP_000735655.1\|2265660_2265885_+	hypothetical protein	NA	NA	NA	NA
WP_000347013.1\|2266241_2266382_+	hypothetical protein	NA	NA	NA	NA
WP_001302977.1\|2266511_2266697_-	DUF3950 domain-containing protein	H6WZK6	Escherichia_phage	3.7e-20	90.4
WP_000279796.1\|2266738_2267104_+	HNH endonuclease	B6ETE5	Enterobacteria_phage	3.1e-66	100.0
WP_000958387.1\|2267395_2267959_+\|terminase	terminase small subunit	A0A0N7KZJ8	Stx2-converting_phage	8.1e-90	100.0
WP_001301491.1\|2267955_2269617_+\|terminase	terminase large subunit	A0A0P0ZD10	Stx2-converting_phage	0.0e+00	100.0
WP_000172999.1\|2269680_2271618_+\|capsid	phage major capsid protein	B6DZ99	Enterobacteria_phage	0.0e+00	100.0
WP_001063099.1\|2271662_2271884_+	hypothetical protein	B6DZA0	Enterobacteria_phage	5.8e-36	100.0
WP_000267292.1\|2271829_2274331_+\|portal	phage portal protein	B6DZA1	Enterobacteria_phage	0.0e+00	99.2
WP_000126019.1\|2274410_2274737_+\|head,tail	phage gp6-like head-tail connector protein	A0A0P0ZDA0	Stx2-converting_phage	9.2e-54	100.0
WP_001007901.1\|2274746_2275097_+\|head	phage head closure protein	A0A0P0ZCU6	Stx2-converting_phage	7.0e-60	100.0
WP_000573374.1\|2275093_2275540_+	HK97 gp10 family phage protein	A0A0P0ZCD2	Stx2-converting_phage	8.1e-77	100.0
WP_000133388.1\|2275536_2275881_+	DUF3168 domain-containing protein	A0A0P0ZC17	Stx2-converting_phage	1.4e-57	100.0
WP_001275434.1\|2275939_2276656_+\|tail	tail protein	A0A0P0ZDV1	Stx2-converting_phage	1.6e-127	100.0
WP_000710952.1\|2276670_2277045_+\|tail	tail assembly protein	A0A0P0ZE84	Stx2-converting_phage	4.6e-65	100.0
WP_001453746.1\|2277140_2277350_+	DUF4035 domain-containing protein	A0A0P0ZED8	Stx2-converting_phage	2.6e-33	100.0
WP_000212827.1\|2277397_2280640_+\|tail	phage tail tape measure protein	A0A0P0ZDY0	Stx2-converting_phage	0.0e+00	100.0
WP_000807954.1\|2280632_2280974_+\|tail	phage tail protein	A0A0P0ZBQ8	Stx2-converting_phage	5.1e-63	100.0
WP_001152182.1\|2280973_2281672_+\|tail	phage minor tail protein L	A0A0P0ZBE3	Stx2-converting_phage	8.1e-132	98.3
WP_000170104.1\|2281688_2281943_-	Arc family DNA-binding protein	NA	NA	NA	NA
WP_010904626.1\|2282052_2282163_+	Arc family DNA-binding protein	NA	NA	NA	NA
WP_000835336.1\|2282465_2283344_+	phage repressor protein/antirepressor Ant	I6R977	Salmonella_phage	2.5e-93	77.2
WP_000967271.1\|2283397_2284135_+\|tail	phage tail protein	B6ETG2	Enterobacteria_phage	8.2e-151	100.0
WP_071526731.1\|2284080_2284317_+\|tail	tail assembly protein	B6ETG3	Enterobacteria_phage	2.8e-20	80.3
WP_115801847.1\|2284329_2284419_+	hypothetical protein	NA	NA	NA	NA
WP_001301673.1\|2284438_2286787_+	type III secretion system effector E3 ubiquitin ligase NleL	NA	NA	NA	NA
WP_001301984.1\|2287377_2290779_+	type III secretion system effector EspN	A0A0N7KZG3	Stx2-converting_phage	1.7e-219	39.2
WP_001301834.1\|2292882_2293008_+	hypothetical protein	Q8HAB2	Salmonella_phage	8.7e-05	58.3
WP_001303921.1\|2293087_2293363_-	hypothetical protein	NA	NA	NA	NA
WP_000938118.1\|2293423_2294785_-	type III secretion system effector EspK	Q9MBM1	Phage_Gifsy-1	1.4e-50	29.2
WP_000799385.1\|2295148_2296012_-	spermidine/putrescine ABC transporter permease PotB	Q6GZ02	Mycoplasma_phage	6.7e-11	28.7
WP_000531594.1\|2295995_2297132_-	spermidine/putrescine ABC transporter ATP-binding protein PotA	Q6GZ03	Mycoplasma_phage	5.5e-29	39.8
WP_000359446.1\|2297381_2298608_+	peptidase T	NA	NA	NA	NA
WP_001301987.1\|2298656_2299778_-	cupin domain-containing protein	NA	NA	NA	NA
WP_085952403.1\|2300139_2301353_-\|transposase	IS3 family transposase	Q6H9S6	Enterobacteria_phage	3.4e-170	99.7
WP_032174463.1\|2301351_2302569_+\|integrase	site-specific integrase	A0A2H4JB45	uncultured_Caudovirales_phage	6.1e-127	56.8
WP_000953272.1\|2302933_2303122_+	AlpA family transcriptional regulator	A0A2H4JB58	uncultured_Caudovirales_phage	2.0e-13	66.0
WP_125090562.1\|2303171_2303498_-	hypothetical protein	NA	NA	NA	NA
WP_000106745.1\|2303622_2303796_-	hypothetical protein	A0A2H4JB52	uncultured_Caudovirales_phage	8.4e-06	51.2
WP_000226782.1\|2303926_2304124_+	host cell division inhibitor Icd-like protein	NA	NA	NA	NA
WP_000609225.1\|2304116_2304329_+	hypothetical protein	NA	NA	NA	NA
WP_000551675.1\|2304318_2304783_+	hypothetical protein	NA	NA	NA	NA
WP_001204985.1\|2304775_2305009_+	hypothetical protein	NA	NA	NA	NA
WP_000770178.1\|2305014_2305314_+	DUF4222 domain-containing protein	NA	NA	NA	NA
WP_000833626.1\|2305310_2306711_+	AAA family ATPase	A0A2H4JFA4	uncultured_Caudovirales_phage	3.6e-115	49.3
WP_000192401.1\|2306911_2307163_+	hypothetical protein	NA	NA	NA	NA
WP_000126695.1\|2307159_2307570_+	single-stranded DNA-binding protein	NA	NA	NA	NA
WP_000233304.1\|2307580_2307853_+	PerC family transcriptional regulator	NA	NA	NA	NA
WP_001132079.1\|2307979_2308204_+	hypothetical protein	NA	NA	NA	NA
WP_000796968.1\|2308455_2308662_+	hypothetical protein	NA	NA	NA	NA
WP_000907465.1\|2308661_2309717_+\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	1.5e-68	43.3
WP_000380883.1\|2309729_2310065_+\|head	head decoration protein	NA	NA	NA	NA
2309826:2309841	attL	NA	NA	NA	NA
WP_000224603.1\|2310077_2310491_+	hypothetical protein	NA	NA	NA	NA
WP_000835281.1\|2310696_2311239_+\|terminase	terminase	O64316	Escherichia_phage	1.8e-33	44.2
WP_000133424.1\|2311494_2311776_+	hypothetical protein	NA	NA	NA	NA
WP_000735407.1\|2312376_2313837_-	two-component system sensor histidine kinase PhoQ	NA	NA	NA	NA
WP_001265474.1\|2313836_2314508_-	two-component system response regulator PhoP	NA	NA	NA	NA
WP_000423729.1\|2314676_2316047_-	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	4.2e-108	44.9
WP_001301618.1\|2316050_2316692_-	high frequency lysogenization protein HflD	NA	NA	NA	NA
WP_001301861.1\|2316727_2317834_-\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_000476093.1\|2317887_2318349_-	phosphatase NudJ	NA	NA	NA	NA
WP_001248690.1\|2318358_2319012_-	23S rRNA pseudouridine(2457) synthase RluE	NA	NA	NA	NA
WP_000444477.1\|2319183_2320434_+	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	3.8e-23	100.0
WP_000741454.1\|2320547_2321690_-\|integrase	tyrosine-type recombinase/integrase	O21940	Phage_21	8.1e-206	100.0
WP_000088657.1\|2321679_2321916_-	excisionase	NA	NA	NA	NA
WP_000945520.1\|2322019_2322844_+	replication protein	A0A0K2FJ31	Enterobacteria_phage	3.8e-96	69.3
WP_000788869.1\|2322840_2323542_+	Replication protein P	A0A0P0ZD31	Stx2-converting_phage	1.3e-129	99.6
WP_000145915.1\|2323538_2323841_+	protein ren	A0A0N6WES4	Escherichia_phage	1.1e-42	95.7
WP_001070446.1\|2323908_2324241_+	SMR family multidrug efflux protein EmrE	NA	NA	NA	NA
WP_001302833.1\|2324305_2324428_+	hypothetical protein	NA	NA	NA	NA
WP_000709077.1\|2324485_2326012_+	recombinase family protein	Q3HQV4	Burkholderia_phage	1.2e-31	31.1
WP_001053040.1\|2326513_2326969_+	hypothetical protein	I6PD71	Cronobacter_phage	8.6e-58	64.9
WP_000224907.1\|2326968_2327139_+	hypothetical protein	K7P7K0	Enterobacteria_phage	5.3e-13	67.9
WP_000774504.1\|2327131_2327422_+	DUF1364 domain-containing protein	K7PGZ6	Enterobacteria_phage	2.8e-46	92.7
WP_001099695.1\|2327418_2327781_+	crossover junction endodeoxyribonuclease RusA	K7PM48	Enterobacteria_phage	7.3e-60	95.7
WP_000971093.1\|2327777_2327918_+	YlcG family protein	K7PHH3	Enterobacteria_phage	7.7e-10	71.1
WP_001097228.1\|2327914_2328604_+	Q antiterminator encoded by prophage CP-933P	I6PDF8	Cronobacter_phage	1.7e-57	48.9
WP_000544528.1\|2328925_2329231_+\|holin	holin	A0A286N2Q5	Klebsiella_phage	7.0e-40	87.6
WP_001180487.1\|2329217_2329694_+	glycoside hydrolase family protein	K7PKV2	Enterobacteria_phage	4.3e-84	95.6
WP_010917798.1\|2329910_2330093_+\|lysis	prophage lysis lipoprotein RzoD	K7PHU6	Enterobacteria_phage	4.7e-15	93.3
WP_000738495.1\|2330183_2330477_-	serum resistance lipoprotein Bor	K7PL54	Enterobacteria_phage	1.5e-47	99.0
WP_000079504.1\|2330768_2331179_-	DUF1398 domain-containing protein	C6ZCX4	Enterobacteria_phage	2.7e-71	98.5
WP_001031427.1\|2331464_2331671_+	hypothetical protein	A0A0K2FJ18	Enterobacteria_phage	5.8e-30	100.0
WP_001300120.1\|2331835_2332030_-	DUF3950 domain-containing protein	A0A0K2FIR8	Escherichia_phage	1.5e-27	98.4
WP_000453564.1\|2332418_2332964_+	DNA-packaging protein	A0A0K2FIG2	Enterobacteria_phage	2.6e-93	97.8
WP_024748455.1\|2332938_2334864_+\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	0.0e+00	99.1
WP_000198153.1\|2334860_2335067_+\|head,tail	head-tail joining protein	A0A2R9YJL2	Escherichia_phage	2.2e-29	98.5
WP_001301524.1\|2335063_2336665_+\|portal	phage portal protein	A0A0K2FJC0	Enterobacteria_phage	1.4e-307	98.7
WP_000123254.1\|2336645_2337965_+	S49 family peptidase	A0A2I6TC87	Escherichia_phage	3.4e-232	98.2
WP_001295978.1\|2337974_2338307_+\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	3.8e-55	99.1
2338080:2338095	attR	NA	NA	NA	NA
WP_000063233.1\|2338361_2339387_+\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	5.6e-190	98.5
WP_000158906.1\|2339428_2339827_+	DNA-packaging protein FI	A0A0K2FIR1	Enterobacteria_phage	3.5e-63	98.5
WP_000752995.1\|2339838_2340192_+\|tail	tail attachment protein	A0A2R9YJJ5	Escherichia_phage	9.9e-62	99.1
WP_000975100.1\|2340203_2340782_+\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	1.3e-79	99.0
WP_000683105.1\|2340778_2341174_+\|tail	tail protein	A0A0K2FIF4	Enterobacteria_phage	1.0e-70	100.0
WP_001143002.1\|2341181_2341922_+\|tail	phage tail protein	A0A0K2FJ05	Enterobacteria_phage	8.3e-127	95.9
WP_000479161.1\|2341937_2342360_+\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	2.4e-70	96.4
WP_000459457.1\|2342341_2342776_+\|tail	phage tail assembly protein T	A0A0K2FJB3	Enterobacteria_phage	6.9e-65	100.0
WP_001509030.1\|2342768_2345318_+\|tail	phage tail tape measure protein	A0A0K2FI43	Enterobacteria_phage	0.0e+00	87.2
WP_000847331.1\|2345314_2345644_+\|tail	phage tail protein	A0A2R9YJM0	Escherichia_phage	2.5e-59	100.0
WP_001152612.1\|2345643_2346342_+\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	2.1e-132	98.7
WP_000194779.1\|2346347_2347091_+\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	2.0e-149	97.6
WP_000090920.1\|2347027_2347660_+\|tail	tail assembly protein	A0A2R9YJH6	Escherichia_phage	1.7e-96	99.5
WP_000515612.1\|2347720_2351119_+	host specificity protein J	K7PKJ2	Enterobacteria_phage	0.0e+00	90.7
WP_001230336.1\|2351185_2351785_+	Ail/Lom family outer membrane beta-barrel protein	A0A291AWV3	Escherichia_phage	3.0e-111	99.5
WP_000279120.1\|2351849_2354765_+	membrane protein	Q6H9S9	Enterobacteria_phage	1.1e-57	98.3
WP_000885630.1\|2354764_2355346_+\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	6.1e-101	93.7
WP_000488340.1\|2355465_2356356_-	manganese catalase family protein	NA	NA	NA	NA
WP_001079482.1\|2356374_2356881_-	ferritin-like domain-containing protein	NA	NA	NA	NA
WP_001166090.1\|2356917_2357418_-	ferritin-like domain-containing protein	NA	NA	NA	NA
WP_000134810.1\|2357496_2357679_-	general stress protein	NA	NA	NA	NA
WP_000239881.1\|2358176_2358845_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_000937476.1\|2358901_2359150_+\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	1.7e-12	76.5
WP_001171554.1\|2359225_2359606_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZBP6	Stx2-converting_phage	1.4e-66	100.0
WP_000612591.1\|2359602_2359950_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	2.2e-61	100.0
WP_000998048.1\|2359999_2361538_+\|transposase	IS66-like element ISEc8 family transposase	A0A0P0ZBS5	Stx2-converting_phage	1.5e-300	100.0
WP_001226373.1\|2361840_2363325_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_001201843.1\|2363511_2364465_-\|protease	omptin family outer membrane protease OmpT	NA	NA	NA	NA

DBSCAN-SWA_8

2449049 : 2516576

Stx2-converting_phage(38.78%)

integrase,holin,terminase,head,capsid,transposase,tail,portal,protease

attL 2448886:2448913|attR 2501048:2501075

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2448886:2448913	attL	NA	NA	NA	NA
WP_000113674.1\|2449049_2450180_-\|integrase	tyrosine-type recombinase/integrase	O21940	Phage_21	3.4e-103	51.4
WP_000113189.1\|2450157_2450406_-	excisionase	NA	NA	NA	NA
WP_153038081.1\|2450470_2452942_-	exonuclease	A0A192Y6E0	Salmonella_phage	1.5e-58	58.6
WP_001090200.1\|2453034_2453226_-	DUF1482 family protein	NA	NA	NA	NA
WP_000449192.1\|2453222_2453411_-	cell division inhibition protein DicB	NA	NA	NA	NA
WP_001356681.1\|2453808_2453976_+	hypothetical protein	NA	NA	NA	NA
WP_000920491.1\|2453969_2454203_+	hypothetical protein	NA	NA	NA	NA
WP_000394552.1\|2454180_2454588_-	hypothetical protein	A0A2R2Z306	Escherichia_phage	7.0e-11	37.8
WP_001171903.1\|2454610_2454829_-	hypothetical protein	NA	NA	NA	NA
WP_001240336.1\|2454901_2455201_-	hypothetical protein	NA	NA	NA	NA
WP_000787428.1\|2455464_2455872_-	helix-turn-helix domain-containing protein	I6PD69	Cronobacter_phage	9.8e-29	49.6
WP_000912298.1\|2455948_2456176_+	transcriptional regulator	NA	NA	NA	NA
WP_000705621.1\|2456159_2456711_+	hypothetical protein	NA	NA	NA	NA
WP_000020556.1\|2456682_2457723_+	DNA-binding protein	A0A0U2RT81	Escherichia_phage	7.9e-91	87.2
WP_001302276.1\|2457754_2458177_+	replication protein	A0A0U2JGJ0	Escherichia_phage	1.2e-77	98.6
WP_000774808.1\|2458363_2458945_+	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	8.6e-79	80.2
WP_001505071.1\|2458941_2459106_+	hypothetical protein	NA	NA	NA	NA
WP_001449026.1\|2459804_2460563_+	AcfC family adhesin Paa	NA	NA	NA	NA
WP_000961820.1\|2460841_2461054_+	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	1.4e-15	70.0
WP_001217394.1\|2461274_2461532_+	hypothetical protein	NA	NA	NA	NA
WP_010917803.1\|2461601_2461880_+	hypothetical protein	I6PCV7	Cronobacter_phage	2.2e-11	48.4
WP_001302148.1\|2461881_2462928_+	DUF968 domain-containing protein	U5P0K4	Shigella_phage	4.2e-108	54.2
WP_000904166.1\|2462940_2463300_+	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	3.6e-35	60.9
WP_000640048.1\|2463308_2463839_+	DUF1133 family protein	A0A0U2S606	Escherichia_phage	9.3e-72	72.6
WP_000917750.1\|2464080_2464278_+	hypothetical protein	S5MQK8	Escherichia_phage	1.0e-28	98.5
WP_000935548.1\|2464428_2465487_+	site-specific DNA-methyltransferase	S5MDR0	Escherichia_phage	1.1e-199	94.3
WP_000143067.1\|2466283_2468137_+	DUF1737 domain-containing protein	H6WZJ9	Escherichia_phage	0.0e+00	97.9
WP_000284517.1\|2468286_2468502_+\|holin	holin	A0A0P0ZC45	Stx2-converting_phage	4.5e-33	98.6
WP_000731259.1\|2468506_2468851_+	YdfR family protein	B6DZ91	Enterobacteria_phage	4.5e-59	100.0
WP_000992137.1\|2468901_2469435_+	lysozyme	B6DZ92	Enterobacteria_phage	3.5e-103	100.0
WP_001056806.1\|2469705_2470275_+	hypothetical protein	A0A1I9LJR6	Stx_converting_phage	3.1e-105	100.0
WP_000539792.1\|2470274_2470421_+	hypothetical protein	A0A0P0ZE99	Stx2-converting_phage	2.6e-16	100.0
WP_012816791.1\|2470648_2470834_+	membrane protein	A0A0P0ZCT3	Stx2-converting_phage	1.2e-18	100.0
WP_000095736.1\|2471258_2471486_-	DUF3950 domain-containing protein	A0A0P0ZE23	Stx2-converting_phage	1.7e-35	100.0
WP_015994246.1\|2471527_2471893_+	HNH endonuclease	B6DZ96	Enterobacteria_phage	1.5e-65	100.0
WP_000958387.1\|2472182_2472746_+\|terminase	terminase small subunit	A0A0N7KZJ8	Stx2-converting_phage	8.1e-90	100.0
WP_001301491.1\|2472742_2474404_+\|terminase	terminase large subunit	A0A0P0ZD10	Stx2-converting_phage	0.0e+00	100.0
WP_000172999.1\|2474467_2476405_+\|capsid	phage major capsid protein	B6DZ99	Enterobacteria_phage	0.0e+00	100.0
WP_001063099.1\|2476449_2476671_+	hypothetical protein	B6DZA0	Enterobacteria_phage	5.8e-36	100.0
WP_000267292.1\|2476616_2479118_+\|portal	phage portal protein	B6DZA1	Enterobacteria_phage	0.0e+00	99.2
WP_000126019.1\|2479197_2479524_+\|head,tail	phage gp6-like head-tail connector protein	A0A0P0ZDA0	Stx2-converting_phage	9.2e-54	100.0
WP_001007901.1\|2479533_2479884_+\|head	phage head closure protein	A0A0P0ZCU6	Stx2-converting_phage	7.0e-60	100.0
WP_000573374.1\|2479880_2480327_+	HK97 gp10 family phage protein	A0A0P0ZCD2	Stx2-converting_phage	8.1e-77	100.0
WP_000133388.1\|2480323_2480668_+	DUF3168 domain-containing protein	A0A0P0ZC17	Stx2-converting_phage	1.4e-57	100.0
WP_001275508.1\|2480726_2481443_+\|tail	tail protein	A0A0P0ZD29	Stx2-converting_phage	2.9e-129	100.0
WP_001030063.1\|2481448_2481823_+\|tail	tail assembly protein	A0A0N7KZA2	Stx2-converting_phage	7.8e-65	100.0
WP_001453698.1\|2481918_2482128_+	DUF4035 domain-containing protein	A0A0P0ZDE6	Stx2-converting_phage	2.0e-33	100.0
WP_064261924.1\|2482180_2485423_+\|tail	phage tail tape measure protein	A0A0P0ZDY0	Stx2-converting_phage	0.0e+00	99.4
WP_000807954.1\|2485415_2485757_+\|tail	phage tail protein	A0A0P0ZBQ8	Stx2-converting_phage	5.1e-63	100.0
WP_001303038.1\|2485756_2486455_+\|tail	phage minor tail protein L	A0A0P0ZBE3	Stx2-converting_phage	1.5e-133	100.0
WP_024748465.1\|2486465_2487209_+\|tail	phage tail protein	A0A0P0ZE89	Stx2-converting_phage	6.6e-148	97.6
WP_129137391.1\|2487154_2487787_+\|tail	tail assembly protein	Q6H9T3	Enterobacteria_phage	3.5e-102	95.7
WP_024748464.1\|2488033_2491513_+	host specificity protein J	B6DZB5	Enterobacteria_phage	0.0e+00	96.1
WP_001230495.1\|2491579_2492179_+	Ail/Lom family outer membrane beta-barrel protein	A0A0P0ZE39	Stx2-converting_phage	3.7e-109	98.0
WP_024748463.1\|2492243_2493557_+\|tail	tail fiber protein	A0A0P0ZCC1	Stx2-converting_phage	6.5e-82	98.6
WP_001023426.1\|2493558_2493828_+\|tail	phage tail protein	B6DZB8	Enterobacteria_phage	1.6e-43	97.8
WP_085952403.1\|2495476_2496690_-\|transposase	IS3 family transposase	Q6H9S6	Enterobacteria_phage	3.4e-170	99.7
WP_001079499.1\|2501225_2501732_-	ferritin-like domain-containing protein	NA	NA	NA	NA
2501048:2501075	attR	NA	NA	NA	NA
WP_001056491.1\|2501777_2502278_-	ferritin-like domain-containing protein	NA	NA	NA	NA
WP_000807651.1\|2502363_2502543_-	general stress protein	NA	NA	NA	NA
WP_000443092.1\|2502923_2503730_-	tryptophan synthase subunit alpha	NA	NA	NA	NA
WP_000209521.1\|2503729_2504923_-	tryptophan synthase subunit beta	NA	NA	NA	NA
WP_001416116.1\|2504934_2506293_-	bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF	A0A0P0IR83	Acinetobacter_phage	7.3e-36	40.3
WP_000763503.1\|2506296_2507892_-	bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD	A0A0N7IRD9	Acinetobacter_phage	5.0e-52	38.2
WP_001194607.1\|2507891_2509454_-	anthranilate synthase component I	NA	NA	NA	NA
WP_001700591.1\|2509545_2509590_-	trp operon leader peptide	NA	NA	NA	NA
WP_001285675.1\|2509727_2510609_+	5'-3' exoribonuclease	NA	NA	NA	NA
WP_001295575.1\|2510605_2511226_+	threonylcarbamoyl-AMP synthase	NA	NA	NA	NA
WP_001302160.1\|2511253_2512837_+	DUF2207 domain-containing protein	NA	NA	NA	NA
WP_001291216.1\|2513049_2513922_+	23S rRNA pseudouridine(2605) synthase RluB	NA	NA	NA	NA
WP_001278878.1\|2513961_2514552_-	cob(I)yrinic acid a,c-diamide adenosyltransferase	NA	NA	NA	NA
WP_000559268.1\|2514548_2515307_-	YciK family oxidoreductase	A0A0N9R355	Chrysochromulina_ericina_virus	6.7e-07	23.9
WP_000422055.1\|2515526_2516576_+\|protease	protease SohB	A0A2H4UUF9	Bodo_saltans_virus	1.3e-21	31.5

DBSCAN-SWA_9

2789286 : 2936635

176

Stx2-converting_phage(30.77%)

holin,integrase,terminase,head,capsid,transposase,tail,portal

attL 2836310:2836357|attR 2939520:2939567

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000214712.1\|2789286_2789490_+	putative selenium delivery protein YdfZ	J9Q802	Salmonella_phage	1.6e-11	55.2
WP_000527769.1\|2789525_2790986_-	mannitol dehydrogenase family protein	H8ZJP8	Ostreococcus_tauri_virus	1.9e-42	29.6
WP_000347470.1\|2791074_2792358_-	MHS family MFS transporter	NA	NA	NA	NA
WP_016241229.1\|2792417_2792732_+	DinI-like family protein	Q687E4	Enterobacteria_phage	2.4e-27	83.3
WP_001143804.1\|2792893_2793535_-	DUF1076 domain-containing protein	B6DZC0	Enterobacteria_phage	3.8e-104	96.7
WP_153038083.1\|2793616_2794207_-	DUF1076 domain-containing protein	B6DZB9	Enterobacteria_phage	7.4e-78	94.0
WP_001131658.1\|2794279_2794855_-	DUF1076 domain-containing protein	H6WZN1	Escherichia_phage	4.1e-89	88.9
WP_001023407.1\|2794968_2795238_-\|tail	phage tail protein	H6WZN0	Escherichia_phage	1.4e-44	98.9
WP_024748460.1\|2795239_2796553_-\|tail	tail fiber protein	A0A0P0ZE15	Stx2-converting_phage	6.9e-76	96.6
WP_001230509.1\|2796617_2797217_-	Ail/Lom family protein	A0A0P0ZE39	Stx2-converting_phage	3.3e-110	99.5
WP_137049505.1\|2797284_2800695_-	host specificity protein J	B6DZB5	Enterobacteria_phage	0.0e+00	99.6
WP_050546863.1\|2800998_2801631_-\|tail	tail assembly protein	A0A0P0ZC16	Stx2-converting_phage	5.8e-105	99.5
WP_024748514.1\|2801576_2802320_-\|tail	phage tail protein	Q6H9T4	Enterobacteria_phage	6.1e-146	96.4
WP_001416783.1\|2802330_2803029_-\|tail	phage minor tail protein L	A0A0P0ZBE3	Stx2-converting_phage	3.1e-131	98.3
WP_000847298.1\|2803028_2803358_-\|tail	phage tail protein	Q687F2	Enterobacteria_phage	4.3e-59	100.0
WP_024748467.1\|2803354_2805967_-\|tail	phage tail tape measure protein	Q687F3	Enterobacteria_phage	0.0e+00	95.8
WP_000533440.1\|2805947_2806361_-\|tail	phage tail assembly protein T	Q687F4	Enterobacteria_phage	3.2e-43	83.2
WP_000479046.1\|2806387_2806810_-\|tail	phage minor tail protein G	Q687F5	Enterobacteria_phage	2.4e-70	97.9
WP_000235090.1\|2806823_2807576_-\|tail	phage tail protein	Q687F6	Enterobacteria_phage	5.8e-136	100.0
WP_000683063.1\|2807583_2807979_-\|tail	tail protein	A0A2R9YJI2	Escherichia_phage	3.3e-58	81.7
WP_000975020.1\|2807975_2808509_-\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	5.9e-58	66.7
WP_000753016.1\|2808523_2808877_-\|tail	tail attachment protein	A0A2R9YJJ5	Escherichia_phage	1.9e-57	92.3
WP_000158906.1\|2808888_2809287_-	DNA-packaging protein FI	A0A0K2FIR1	Enterobacteria_phage	3.5e-63	98.5
WP_024748468.1\|2809328_2810354_-\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	9.6e-190	98.5
WP_001295978.1\|2810409_2810742_-\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	3.8e-55	99.1
WP_000123254.1\|2810751_2812071_-	S49 family peptidase	A0A2I6TC87	Escherichia_phage	3.4e-232	98.2
WP_001301524.1\|2812051_2813653_-\|portal	phage portal protein	A0A0K2FJC0	Enterobacteria_phage	1.4e-307	98.7
WP_000198153.1\|2813649_2813856_-\|head,tail	head-tail joining protein	A0A2R9YJL2	Escherichia_phage	2.2e-29	98.5
WP_153038084.1\|2813852_2815778_-\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	0.0e+00	97.8
WP_000867498.1\|2815752_2816298_-\|terminase	terminase small subunit	A0A0K2FIG2	Enterobacteria_phage	9.6e-80	83.3
WP_001303940.1\|2816684_2816909_+	DUF3950 domain-containing protein	A0A0K2FIR8	Escherichia_phage	1.7e-19	90.6
WP_001302717.1\|2816990_2817305_-	PerC family transcriptional regulator	NA	NA	NA	NA
WP_001208680.1\|2817830_2818016_-	membrane protein	A0A1U9AJA4	Stx1_converting_phage	1.7e-20	80.3
WP_000539795.1\|2818238_2818385_-	hypothetical protein	A0A0P0ZG36	Escherichia_phage	1.1e-11	87.0
WP_001056806.1\|2818384_2818954_-	hypothetical protein	A0A1I9LJR6	Stx_converting_phage	3.1e-105	100.0
WP_000992137.1\|2819224_2819758_-	lysozyme	B6DZ92	Enterobacteria_phage	3.5e-103	100.0
WP_000731259.1\|2819808_2820153_-	YdfR family protein	B6DZ91	Enterobacteria_phage	4.5e-59	100.0
WP_000411805.1\|2820157_2820364_-\|holin	holin	A0A0P0ZC45	Stx2-converting_phage	4.0e-31	98.5
WP_000023184.1\|2820812_2822663_-	SASA family carbohydrate esterase	B6DZ89	Enterobacteria_phage	0.0e+00	98.9
WP_001302123.1\|2823140_2823572_-	tellurite resistance protein	H6WZJ6	Escherichia_phage	1.6e-66	96.5
WP_000301797.1\|2824022_2824736_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_000917763.1\|2824871_2825069_-	hypothetical protein	S5MQK8	Escherichia_phage	8.9e-28	96.9
WP_000640035.1\|2825293_2825848_-	DUF1133 family protein	A0A0U2S606	Escherichia_phage	1.0e-65	67.4
WP_001217444.1\|2825910_2826216_-	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	7.1e-32	66.3
WP_001265229.1\|2826228_2827278_-	DUF968 domain-containing protein	U5P0K4	Shigella_phage	1.2e-110	54.6
WP_000191872.1\|2827279_2827552_-	hypothetical protein	S4TNP0	Salmonella_phage	1.1e-12	53.0
WP_000756596.1\|2827673_2828018_-	YgiW/YdeI family stress tolerance OB fold protein	A0A1I9LJU6	Stx_converting_phage	6.1e-56	99.1
WP_000935259.1\|2828137_2828350_-	type I toxin-antitoxin system Hok family toxin	A0A0P0ZAX5	Stx2-converting_phage	6.0e-30	100.0
WP_000104474.1\|2828583_2829141_-	DUF551 domain-containing protein	A0A0N7KZV3	Escherichia_phage	2.8e-34	41.7
WP_000683609.1\|2829142_2829361_-	DUF4014 domain-containing protein	A0A2R2Z311	Escherichia_phage	2.3e-21	72.2
WP_001289673.1\|2829488_2829800_-	hypothetical protein	A0A0U2QV73	Escherichia_phage	7.2e-56	92.2
WP_000699809.1\|2829792_2830020_-	hypothetical protein	A0A1B5FPG2	Escherichia_phage	5.1e-11	49.3
WP_000603384.1\|2830016_2830298_-	DNA-binding protein	A0A222YXX1	Escherichia_phage	1.0e-29	73.6
WP_000450627.1\|2830330_2831047_-	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	3.3e-72	62.8
WP_001379651.1\|2831080_2831503_-	replication protein	A0A0U2JGJ0	Escherichia_phage	5.7e-72	90.0
WP_001262402.1\|2831534_2832578_-	hypothetical protein	A0A0U2RT81	Escherichia_phage	1.4e-82	65.1
WP_000693878.1\|2832646_2833072_-	Rha family transcriptional regulator	NA	NA	NA	NA
WP_000747948.1\|2833055_2833298_-	hypothetical protein	H9C161	Pectobacterium_phage	4.8e-07	55.8
WP_001416688.1\|2833689_2834028_+	peptidase S24	H9C160	Pectobacterium_phage	1.9e-06	30.1
WP_000380316.1\|2834320_2834473_+	DUF1391 domain-containing protein	M4QQ57	Salicola_phage	5.1e-07	53.2
WP_000394548.1\|2834484_2835123_+	hypothetical protein	A0A2R2Z306	Escherichia_phage	2.5e-07	41.9
WP_001133037.1\|2835123_2835333_-	hypothetical protein	NA	NA	NA	NA
WP_000449175.1\|2835897_2836086_+	cell division inhibitor	NA	NA	NA	NA
WP_000199475.1\|2836082_2836271_+	DUF1482 family protein	NA	NA	NA	NA
2836310:2836357	attL	NA	NA	NA	NA
WP_000102123.1\|2836363_2837608_+	exonuclease	H6WRX1	Salmonella_phage	1.4e-86	50.3
WP_016241229.1\|2838246_2838561_+	DinI-like family protein	Q687E4	Enterobacteria_phage	2.4e-27	83.3
WP_001171554.1\|2839523_2839904_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZBP6	Stx2-converting_phage	1.4e-66	100.0
WP_000612591.1\|2839900_2840248_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	2.2e-61	100.0
WP_000998048.1\|2840297_2841836_+\|transposase	IS66-like element ISEc8 family transposase	A0A0P0ZBS5	Stx2-converting_phage	1.5e-300	100.0
WP_001121225.1\|2842418_2843069_-	DUF1076 domain-containing protein	B6ETE1	Enterobacteria_phage	1.2e-121	99.1
WP_001131642.1\|2843778_2844354_-	DUF1076 domain-containing protein	H6WZN1	Escherichia_phage	4.1e-57	60.5
WP_001023362.1\|2844467_2844737_-\|tail	phage tail protein	H6WZN0	Escherichia_phage	6.4e-45	98.9
WP_153038085.1\|2844738_2845908_-\|tail	phage tail protein	B6DZB7	Enterobacteria_phage	3.6e-84	99.5
WP_001230509.1\|2845972_2846572_-	Ail/Lom family protein	A0A0P0ZE39	Stx2-converting_phage	3.3e-110	99.5
WP_001304111.1\|2846639_2846855_-	hypothetical protein	Q9LA64	Enterobacterial_phage	1.0e-32	97.2
WP_012779365.1\|2846857_2850118_-	host specificity protein J	A0A0P0ZBW1	Stx2-converting_phage	0.0e+00	92.3
WP_024748472.1\|2850305_2850743_-\|tail	phage minor tail protein L	Q6H9T5	Enterobacteria_phage	5.0e-63	100.0
WP_000807954.1\|2850742_2851084_-\|tail	phage tail protein	A0A0P0ZBQ8	Stx2-converting_phage	5.1e-63	100.0
WP_000212827.1\|2851076_2854319_-\|tail	phage tail tape measure protein	A0A0P0ZDY0	Stx2-converting_phage	0.0e+00	100.0
WP_001453746.1\|2854366_2854576_-	DUF4035 domain-containing protein	A0A0P0ZED8	Stx2-converting_phage	2.6e-33	100.0
WP_000710952.1\|2854671_2855046_-\|tail	tail assembly protein	A0A0P0ZE84	Stx2-converting_phage	4.6e-65	100.0
WP_001275434.1\|2855060_2855777_-\|tail	tail protein	A0A0P0ZDV1	Stx2-converting_phage	1.6e-127	100.0
WP_000133388.1\|2855835_2856180_-	DUF3168 domain-containing protein	A0A0P0ZC17	Stx2-converting_phage	1.4e-57	100.0
WP_000573374.1\|2856176_2856623_-	HK97 gp10 family phage protein	A0A0P0ZCD2	Stx2-converting_phage	8.1e-77	100.0
WP_001007901.1\|2856619_2856970_-\|head	phage head closure protein	A0A0P0ZCU6	Stx2-converting_phage	7.0e-60	100.0
WP_000126019.1\|2856979_2857306_-\|head,tail	phage gp6-like head-tail connector protein	A0A0P0ZDA0	Stx2-converting_phage	9.2e-54	100.0
WP_000267292.1\|2857385_2859887_-\|portal	phage portal protein	B6DZA1	Enterobacteria_phage	0.0e+00	99.2
WP_001063099.1\|2859832_2860054_-	hypothetical protein	B6DZA0	Enterobacteria_phage	5.8e-36	100.0
WP_000172999.1\|2860098_2862036_-\|capsid	phage major capsid protein	B6DZ99	Enterobacteria_phage	0.0e+00	100.0
WP_001301491.1\|2862099_2863761_-\|terminase	terminase large subunit	A0A0P0ZD10	Stx2-converting_phage	0.0e+00	100.0
WP_000958387.1\|2863757_2864321_-\|terminase	terminase small subunit	A0A0N7KZJ8	Stx2-converting_phage	8.1e-90	100.0
WP_001303046.1\|2864609_2864975_-	HNH endonuclease	A0A0P0ZCH0	Stx2-converting_phage	2.0e-65	100.0
WP_000074669.1\|2865016_2865241_+	DUF3950 domain-containing protein	A0A0K2FIR8	Escherichia_phage	2.7e-20	92.5
WP_001303878.1\|2865322_2865637_-	PerC family transcriptional regulator	NA	NA	NA	NA
WP_001208680.1\|2866164_2866350_-	membrane protein	A0A1U9AJA4	Stx1_converting_phage	1.7e-20	80.3
WP_000075112.1\|2866566_2867064_-	lysozyme	A0A0N7KZA0	Stx2-converting_phage	9.9e-92	99.4
WP_000411802.1\|2867063_2867270_-\|holin	holin	A0A0P0ZC45	Stx2-converting_phage	2.4e-31	100.0
WP_024748518.1\|2867717_2869568_-	SASA family carbohydrate esterase	B6DZ89	Enterobacteria_phage	0.0e+00	99.2
WP_000483497.1\|2870059_2871118_-	site-specific DNA-methyltransferase	S5MDR0	Escherichia_phage	2.3e-207	99.1
WP_000917735.1\|2871268_2871466_-	hypothetical protein	S5MQK8	Escherichia_phage	1.8e-28	98.5
WP_000762904.1\|2871692_2872514_-	antitermination protein	K7P7B9	Enterobacteria_phage	1.2e-81	61.2
WP_000904137.1\|2872510_2872885_-	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	2.4e-34	62.7
WP_001304183.1\|2873948_2874227_-	hypothetical protein	I6PCV7	Cronobacter_phage	1.1e-10	46.9
WP_000967408.1\|2874756_2874969_-	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	1.1e-26	94.3
WP_001278450.1\|2875157_2875262_-	hypothetical protein	NA	NA	NA	NA
WP_000610379.1\|2875377_2875740_-	DUF551 domain-containing protein	A0A0P0ZCX1	Stx2-converting_phage	8.6e-69	98.3
WP_000137941.1\|2875736_2876108_-	hypothetical protein	A0A0N7KZJ2	Stx2-converting_phage	1.3e-48	78.0
WP_000063625.1\|2876143_2876356_-	hypothetical protein	A0A2R2Z310	Escherichia_phage	1.4e-31	87.1
WP_001302146.1\|2876404_2876761_-	hypothetical protein	A0A2R2Z307	Escherichia_phage	3.7e-56	94.9
WP_001118161.1\|2876817_2877213_-	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	1.0e-30	51.4
WP_000450888.1\|2877228_2877999_-	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	3.8e-82	66.0
WP_000790456.1\|2878028_2878769_-	DNA replication protein DnaC	V5UQI5	Shigella_phage	7.8e-117	85.6
WP_000095667.1\|2878775_2879729_-	DNA-binding protein	U5P0A0	Shigella_phage	5.2e-73	51.7
WP_000693888.1\|2879751_2880177_-	Rha family transcriptional regulator	NA	NA	NA	NA
WP_024213789.1\|2880160_2880436_-	Rha family transcriptional regulator	A0A0M4QX15	Salmonella_phage	1.1e-15	54.8
WP_000367559.1\|2880538_2880928_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_000380314.1\|2881097_2881250_+	DUF1391 domain-containing protein	M4QQ57	Salicola_phage	2.5e-06	51.1
WP_000450222.1\|2881737_2881926_+	cell division inhibitor	NA	NA	NA	NA
WP_000092782.1\|2881922_2882111_+	DUF1482 family protein	NA	NA	NA	NA
WP_000102181.1\|2882203_2884648_+	exonuclease	V5UQJ3	Shigella_phage	2.2e-176	58.5
WP_000113189.1\|2884712_2884961_+	excisionase	NA	NA	NA	NA
WP_001500821.1\|2884938_2886069_+\|integrase	tyrosine-type recombinase/integrase	O21940	Phage_21	4.9e-102	50.9
WP_000147167.1\|2886556_2886775_+	hypothetical protein	NA	NA	NA	NA
WP_001302903.1\|2887368_2887797_-	DUF1076 domain-containing protein	B6DZB9	Enterobacteria_phage	1.4e-22	42.1
WP_001144877.1\|2889525_2890116_-	T3SS effector guanine nucleotide exchange factor EspM1	NA	NA	NA	NA
WP_001303944.1\|2890299_2890947_+	T3SS effector E3 ubiquitin-protein ligase NleG	B6ETE1	Enterobacteria_phage	1.6e-41	41.1
WP_001414184.1\|2891083_2891230_-	hypothetical protein	NA	NA	NA	NA
WP_001303943.1\|2891657_2891936_+	hypothetical protein	NA	NA	NA	NA
WP_001171554.1\|2892275_2892656_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZBP6	Stx2-converting_phage	1.4e-66	100.0
WP_000612591.1\|2892652_2893000_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	2.2e-61	100.0
WP_000998048.1\|2893049_2894588_+\|transposase	IS66-like element ISEc8 family transposase	A0A0P0ZBS5	Stx2-converting_phage	1.5e-300	100.0
WP_001025672.1\|2897252_2898578_+	type III secretion system effector NleA	H6WZN2	Escherichia_phage	1.9e-214	81.2
WP_001023474.1\|2899604_2899874_-\|tail	phage tail protein	A0A1U9AJC2	Stx1_converting_phage	3.2e-44	98.9
WP_024748516.1\|2899875_2901189_-\|tail	tail fiber protein	A0A0P0ZE15	Stx2-converting_phage	7.2e-81	98.2
WP_001228304.1\|2901340_2901940_-	outer membrane protein	Q9EV15	Enterobacteria_phage	1.6e-107	96.5
WP_129137390.1\|2902007_2904353_-	host specificity protein J	Q9EYE7	Enterobacteria_phage	0.0e+00	99.7
WP_001304109.1\|2904304_2905480_-	host specificity protein J	Q9EYE6	Enterobacteria_phage	1.2e-228	96.9
WP_050439450.1\|2905822_2906455_-\|tail	tail assembly protein	B6ETG3	Enterobacteria_phage	3.9e-101	97.1
WP_046671488.1\|2906400_2907144_-\|tail	phage tail protein	A0A0P0ZE89	Stx2-converting_phage	7.7e-149	98.4
WP_001303038.1\|2907154_2907853_-\|tail	phage minor tail protein L	A0A0P0ZBE3	Stx2-converting_phage	1.5e-133	100.0
WP_000807954.1\|2907852_2908194_-\|tail	phage tail protein	A0A0P0ZBQ8	Stx2-converting_phage	5.1e-63	100.0
WP_064261924.1\|2908186_2911429_-\|tail	phage tail tape measure protein	A0A0P0ZDY0	Stx2-converting_phage	0.0e+00	99.4
WP_001453698.1\|2911481_2911691_-	DUF4035 domain-containing protein	A0A0P0ZDE6	Stx2-converting_phage	2.0e-33	100.0
WP_001030063.1\|2911786_2912161_-\|tail	tail assembly protein	A0A0N7KZA2	Stx2-converting_phage	7.8e-65	100.0
WP_001275508.1\|2912166_2912883_-\|tail	tail protein	A0A0P0ZD29	Stx2-converting_phage	2.9e-129	100.0
WP_000133388.1\|2912941_2913286_-	DUF3168 domain-containing protein	A0A0P0ZC17	Stx2-converting_phage	1.4e-57	100.0
WP_000573374.1\|2913282_2913729_-	HK97 gp10 family phage protein	A0A0P0ZCD2	Stx2-converting_phage	8.1e-77	100.0
WP_001007901.1\|2913725_2914076_-\|head	phage head closure protein	A0A0P0ZCU6	Stx2-converting_phage	7.0e-60	100.0
WP_000126019.1\|2914085_2914412_-\|head,tail	phage gp6-like head-tail connector protein	A0A0P0ZDA0	Stx2-converting_phage	9.2e-54	100.0
WP_000267292.1\|2914491_2916993_-\|portal	phage portal protein	B6DZA1	Enterobacteria_phage	0.0e+00	99.2
WP_001063099.1\|2916938_2917160_-	hypothetical protein	B6DZA0	Enterobacteria_phage	5.8e-36	100.0
WP_000172999.1\|2917204_2919142_-\|capsid	phage major capsid protein	B6DZ99	Enterobacteria_phage	0.0e+00	100.0
WP_024748457.1\|2919205_2920867_-\|terminase	terminase large subunit	A0A0P0ZD10	Stx2-converting_phage	0.0e+00	99.5
WP_001303051.1\|2920863_2921427_-\|terminase	terminase small subunit	B6DZ97	Enterobacteria_phage	2.8e-90	99.5
WP_015994246.1\|2921716_2922082_-	HNH endonuclease	B6DZ96	Enterobacteria_phage	1.5e-65	100.0
WP_000095736.1\|2922123_2922351_+	DUF3950 domain-containing protein	A0A0P0ZE23	Stx2-converting_phage	1.7e-35	100.0
WP_012816791.1\|2922775_2922961_-	membrane protein	A0A0P0ZCT3	Stx2-converting_phage	1.2e-18	100.0
WP_000539792.1\|2923188_2923335_-	hypothetical protein	A0A0P0ZE99	Stx2-converting_phage	2.6e-16	100.0
WP_001056806.1\|2923334_2923904_-	hypothetical protein	A0A1I9LJR6	Stx_converting_phage	3.1e-105	100.0
WP_000992137.1\|2924174_2924708_-	lysozyme	B6DZ92	Enterobacteria_phage	3.5e-103	100.0
WP_000731259.1\|2924758_2925103_-	YdfR family protein	B6DZ91	Enterobacteria_phage	4.5e-59	100.0
WP_000411805.1\|2925107_2925314_-\|holin	holin	A0A0P0ZC45	Stx2-converting_phage	4.0e-31	98.5
WP_024748470.1\|2925762_2927613_-	SASA family carbohydrate esterase	B6DZ89	Enterobacteria_phage	0.0e+00	98.2
WP_001303509.1\|2928091_2928520_-	tellurite resistance protein	H6WZJ6	Escherichia_phage	4.4e-64	97.8
WP_001059381.1\|2929155_2929845_-	antiterminator	I6PDF8	Cronobacter_phage	4.0e-59	51.1
WP_001217455.1\|2929841_2930201_-	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	5.9e-38	67.5
WP_001265161.1\|2930213_2931263_-	DUF968 domain-containing protein	U5P0K4	Shigella_phage	1.4e-108	53.7
WP_012779366.1\|2931264_2931543_-	hypothetical protein	I6PCV7	Cronobacter_phage	5.7e-12	48.4
WP_000887477.1\|2931710_2931923_-	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	3.1e-18	68.6
WP_001278450.1\|2932111_2932216_-	hypothetical protein	NA	NA	NA	NA
WP_000206793.1\|2932331_2932916_-	DUF551 domain-containing protein	A0A0P0ZD75	Stx2-converting_phage	1.9e-33	84.8
WP_001118159.1\|2932972_2933368_-	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	7.8e-31	51.4
WP_000788936.1\|2934178_2934919_-	DNA replication protein DnaC	A0A088CBP4	Shigella_phage	2.3e-124	89.8
WP_000095670.1\|2934925_2935888_-	DNA-binding protein	U5P0A0	Shigella_phage	1.8e-81	57.0
WP_000693943.1\|2935910_2936336_-	Rha family transcriptional regulator	NA	NA	NA	NA
WP_000172738.1\|2936332_2936635_-	transcriptional regulator	K7PHA1	Enterobacteria_phage	8.6e-06	34.8
2939520:2939567	attR	NA	NA	NA	NA

DBSCAN-SWA_10

3250194 : 3302629

Enterobacteria_phage(64.52%)

integrase,transposase,tail,tRNA

attL 3243418:3243433|attR 3302708:3302723

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3243418:3243433	attL	NA	NA	NA	NA
WP_001025318.1\|3250194_3251928_+\|tRNA	arginine--tRNA ligase	A0A2K9L6Z2	Tupanvirus	4.0e-87	33.7
WP_001302043.1\|3252104_3252593_+	lysozyme inhibitor LprI family protein	NA	NA	NA	NA
WP_001259575.1\|3252712_3253105_-	flagellar protein FlhE	NA	NA	NA	NA
WP_000067016.1\|3253104_3255183_-	flagellar biosynthesis protein FlhA	NA	NA	NA	NA
WP_001278932.1\|3255175_3256324_-	flagellar type III secretion system protein FlhB	NA	NA	NA	NA
WP_000983602.1\|3256525_3257170_-	protein phosphatase CheZ	NA	NA	NA	NA
WP_000763867.1\|3257180_3257570_-	chemotaxis protein CheY	A0A2K9L4R0	Tupanvirus	1.3e-06	32.0
WP_000036370.1\|3257584_3258634_-	chemotaxis response regulator protein-glutamate methylesterase	Q56AR1	Bacillus_thuringiensis_phage	1.0e-05	32.8
WP_000204340.1\|3258636_3259497_-	protein-glutamate O-methyltransferase CheR	NA	NA	NA	NA
WP_000483251.1\|3259515_3261117_-	methyl-accepting chemotaxis protein IV	A0A2H4J162	uncultured_Caudovirales_phage	5.4e-14	29.8
WP_001302081.1\|3261162_3262824_-	methyl-accepting chemotaxis protein II	A0A2H4J162	uncultured_Caudovirales_phage	5.8e-11	38.4
WP_000147302.1\|3262966_3263470_-	chemotaxis protein CheW	NA	NA	NA	NA
WP_001322280.1\|3263490_3265455_-	chemotaxis protein CheA	NA	NA	NA	NA
WP_000795630.1\|3265459_3266386_-	motility protein MotB	NA	NA	NA	NA
WP_000906325.1\|3266382_3267270_-	flagellar motor stator protein MotA	NA	NA	NA	NA
WP_001291603.1\|3267396_3267975_-	flagellar transcriptional regulator FlhC	NA	NA	NA	NA
WP_001302091.1\|3267977_3268328_-	flagellar transcriptional regulator FlhD	NA	NA	NA	NA
WP_000122432.1\|3269107_3269536_+	universal stress protein UspC	NA	NA	NA	NA
WP_001295646.1\|3269542_3270967_-	alpha,alpha-trehalose-phosphate synthase	NA	NA	NA	NA
WP_001302045.1\|3270941_3271742_-	trehalose-phosphatase	NA	NA	NA	NA
WP_001302082.1\|3271908_3272895_-	L-arabinose ABC transporter permease AraH	NA	NA	NA	NA
WP_001187819.1\|3272909_3274424_-	L-arabinose ABC transporter ATP-binding protein AraG	A0A2H4PQG7	Staphylococcus_phage	4.3e-13	27.1
WP_000548680.1\|3274493_3275483_-	arabinose ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000179469.1\|3276279_3276783_+	non-heme ferritin-like protein	NA	NA	NA	NA
WP_000084172.1\|3276862_3277114_-	DUF2766 domain-containing protein	NA	NA	NA	NA
WP_010723106.1\|3277228_3277315_-	stress response protein AzuC	NA	NA	NA	NA
WP_001237873.1\|3277576_3277900_+	hypothetical protein	NA	NA	NA	NA
WP_000917208.1\|3278070_3278568_+	non-heme ferritin	NA	NA	NA	NA
WP_000377224.1\|3278604_3278844_-	YecH family protein	NA	NA	NA	NA
WP_000797566.1\|3279035_3280247_+	tyrosine transporter TyrP	NA	NA	NA	NA
WP_000847882.1\|3280308_3280974_-	UPF0149 family protein YecA	NA	NA	NA	NA
WP_001303019.1\|3281330_3282332_-\|integrase	tyrosine-type recombinase/integrase	Q94N03	Haemophilus_virus	3.5e-104	59.1
WP_000865208.1\|3282337_3282685_-	DUF2511 domain-containing protein	NA	NA	NA	NA
WP_000290345.1\|3282714_3283365_-	hypothetical protein	NA	NA	NA	NA
WP_000786773.1\|3283380_3283785_-	transcriptional regulator	Q6QID2	Burkholderia_phage	2.7e-23	53.8
WP_001673482.1\|3283874_3284012_-	hypothetical protein	NA	NA	NA	NA
WP_000014504.1\|3284083_3284287_+	DNA-binding protein	P79674	Haemophilus_phage	3.1e-07	45.2
WP_000739029.1\|3284308_3284659_+	DUF4761 family protein	A0A0A7NV42	Enterobacteria_phage	8.6e-50	81.9
WP_000159449.1\|3284669_3284948_+	hypothetical protein	A0A0A7NRX5	Enterobacteria_phage	4.8e-35	80.4
WP_000514287.1\|3284959_3285202_+	DUF4754 domain-containing protein	A0A0A7NQ71	Enterobacteria_phage	1.2e-37	98.8
WP_000021655.1\|3285198_3285312_+	hypothetical protein	A0A0A7NPW7	Enterobacteria_phage	6.2e-10	100.0
WP_000991913.1\|3285404_3285821_+	hypothetical protein	NA	NA	NA	NA
WP_000985157.1\|3285844_3286048_+	hypothetical protein	A0A0A7NPS8	Enterobacteria_phage	2.5e-25	83.6
WP_000153707.1\|3286044_3286311_+	winged helix-turn-helix transcriptional regulator	A0A0A7NV47	Enterobacteria_phage	3.1e-31	77.3
WP_000104305.1\|3286307_3286607_+	hypothetical protein	A0A0A7NRX6	Enterobacteria_phage	1.6e-41	89.9
WP_000775057.1\|3286929_3287160_+	derepression protein	A0A0A7NV48	Enterobacteria_phage	5.9e-31	94.7
WP_000599379.1\|3287232_3287598_+	hypothetical protein	A0A0A7NRY1	Enterobacteria_phage	6.6e-61	96.7
WP_000123463.1\|3287604_3290427_+	replication endonuclease	A0A0A7NQ77	Enterobacteria_phage	0.0e+00	97.7
WP_000686523.1\|3290503_3291463_+	recombinase	A0A0A7NPX4	Enterobacteria_phage	1.2e-178	99.1
WP_000211280.1\|3291467_3291782_+	peptide transporter	A0A0A7NPT5	Enterobacteria_phage	1.1e-19	52.9
WP_000257965.1\|3292987_3293404_+\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	3.6e-63	84.7
WP_000954203.1\|3293447_3294020_-	serine acetyltransferase	A0A1L2JYI5	Streptococcus_phage	1.0e-07	34.4
WP_000979955.1\|3294176_3294665_-\|tail	phage tail protein	A0A0A7NV65	Enterobacteria_phage	1.0e-85	100.0
WP_085952403.1\|3295176_3296390_-\|transposase	IS3 family transposase	Q6H9S6	Enterobacteria_phage	3.4e-170	99.7
WP_000763327.1\|3298780_3298909_-\|tail	GpE family phage tail protein	A0A0A7NQ96	Enterobacteria_phage	3.0e-16	97.6
WP_000665314.1\|3298944_3299310_-\|tail	tail protein	A0A0A7NPZ0	Enterobacteria_phage	1.7e-56	98.3
WP_000290456.1\|3299364_3299877_-\|tail	phage major tail tube protein	A0A0A7NPV8	Enterobacteria_phage	2.1e-92	99.4
WP_000005444.1\|3299876_3301061_-\|tail	phage tail sheath family protein	A0A0A7NV69	Enterobacteria_phage	1.7e-219	96.7
WP_000132765.1\|3301218_3301542_+	phage late control D family protein	A0A0A7NQ97	Enterobacteria_phage	2.1e-42	97.8
WP_032161583.1\|3301492_3302629_-\|transposase	IS30-like element IS30 family transposase	W5R8L2	Staphylococcus_phage	2.0e-42	35.6
3302708:3302723	attR	NA	NA	NA	NA

DBSCAN-SWA_11

3360200 : 3427271

Enterobacteria_phage(31.11%)

holin,integrase,terminase,head,transposase,tail,portal

attL 3375864:3375879|attR 3431616:3431631

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001023396.1\|3360200_3360470_-\|tail	phage tail protein	B6DZB8	Enterobacteria_phage	3.8e-45	100.0
WP_153038086.1\|3360471_3361641_-\|tail	phage tail protein	B6DZB7	Enterobacteria_phage	2.8e-84	97.4
WP_001230509.1\|3361705_3362305_-	Ail/Lom family protein	A0A0P0ZE39	Stx2-converting_phage	3.3e-110	99.5
WP_000514788.1\|3362372_3365852_-	host specificity protein J	B6DZB5	Enterobacteria_phage	0.0e+00	99.6
WP_129137391.1\|3366098_3366731_-\|tail	tail assembly protein	Q6H9T3	Enterobacteria_phage	3.5e-102	95.7
WP_153038087.1\|3366676_3367420_-\|tail	phage tail protein	A0A0P0ZE89	Stx2-converting_phage	1.5e-144	96.0
WP_001151105.1\|3367430_3368129_-\|tail	phage minor tail protein L	A0A0P0ZBE3	Stx2-converting_phage	1.2e-130	97.8
WP_000847298.1\|3368128_3368458_-\|tail	phage tail protein	Q687F2	Enterobacteria_phage	4.3e-59	100.0
WP_128484525.1\|3368454_3371034_-\|tail	phage tail tape measure protein	A0A2R9YJM8	Escherichia_phage	0.0e+00	79.7
WP_000533402.1\|3371014_3371428_-\|tail	phage tail assembly protein T	S5MDP5	Escherichia_phage	1.6e-42	82.2
WP_000479117.1\|3371454_3371886_-\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	2.4e-41	68.1
WP_029208397.1\|3371899_3372640_-\|tail	phage tail protein	Q687F6	Enterobacteria_phage	3.6e-130	98.0
WP_001301534.1\|3372621_3372888_-	hypothetical protein	NA	NA	NA	NA
WP_000256723.1\|3372945_3373293_-\|head	head decoration protein	C6ZCY1	Enterobacteria_phage	2.6e-22	58.1
WP_001254002.1\|3373329_3374835_-	S49 family peptidase	A0A2I6TC87	Escherichia_phage	1.2e-100	54.2
WP_000831796.1\|3374824_3376417_-\|portal	phage portal protein	K7P6U7	Enterobacteria_phage	8.7e-182	60.5
3375864:3375879	attL	NA	NA	NA	NA
WP_000259002.1\|3376413_3376620_-\|head,tail	head-tail joining protein	K7PM10	Enterobacteria_phage	7.9e-11	56.9
WP_001302857.1\|3376603_3378532_-\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	3.3e-260	65.9
WP_000235436.1\|3378503_3379013_-\|terminase	terminase	A0A1I9KFT4	Aeromonas_phage	1.6e-12	32.7
WP_001299328.1\|3379407_3379632_+	DUF3950 domain-containing protein	A0A0K2FIR8	Escherichia_phage	4.1e-21	92.7
WP_001302690.1\|3379713_3380028_-	PerC family transcriptional regulator	NA	NA	NA	NA
WP_001208680.1\|3380554_3380740_-	membrane protein	A0A1U9AJA4	Stx1_converting_phage	1.7e-20	80.3
WP_001280929.1\|3380967_3381099_-	hypothetical protein	A0A0N7BYT9	Escherichia_phage	9.4e-10	88.4
WP_001303555.1\|3381111_3381294_-	hypothetical protein	NA	NA	NA	NA
WP_000992126.1\|3381449_3381983_-	lysozyme	A0A0N7KZF9	Stx2-converting_phage	1.4e-99	97.7
WP_000731204.1\|3382033_3382378_-	YdfR family protein	B6DZ91	Enterobacteria_phage	1.7e-58	99.1
WP_000411809.1\|3382382_3382589_-\|holin	holin	Q6H9V8	Enterobacteria_phage	2.4e-31	100.0
WP_085948178.1\|3382908_3384121_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_000023257.1\|3384203_3386054_-	SASA family carbohydrate esterase	B6DZ89	Enterobacteria_phage	0.0e+00	96.4
WP_001059369.1\|3387593_3388283_-	antiterminator	I6PDF8	Cronobacter_phage	1.5e-58	51.1
WP_000904141.1\|3388279_3388639_-	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	1.5e-36	64.9
WP_001265075.1\|3388651_3389701_-	DUF968 domain-containing protein	U5P0K4	Shigella_phage	1.3e-109	54.9
WP_001310296.1\|3389702_3389981_-	hypothetical protein	I6PCV7	Cronobacter_phage	1.3e-11	48.4
WP_000902687.1\|3390148_3390361_-	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	7.6e-25	90.0
WP_001278460.1\|3390547_3390652_-	hypothetical protein	NA	NA	NA	NA
WP_000137954.1\|3390761_3391325_-	hypothetical protein	H6WZG0	Escherichia_phage	4.5e-48	94.9
WP_000111243.1\|3391451_3391763_-	hypothetical protein	A0A222YY67	Escherichia_phage	2.4e-51	83.5
WP_001414276.1\|3391759_3391912_-	hypothetical protein	NA	NA	NA	NA
WP_001290006.1\|3391944_3392301_-	hypothetical protein	A0A222YY85	Escherichia_phage	3.1e-15	65.8
WP_000702797.1\|3392297_3392522_-	hypothetical protein	A0A1B5FPG2	Escherichia_phage	3.6e-09	42.3
WP_000450610.1\|3392543_3393242_-	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	1.6e-71	59.5
WP_000373320.1\|3393276_3393699_-	hypothetical protein	A0A0U2JGJ0	Escherichia_phage	5.0e-76	96.4
WP_024748451.1\|3393730_3394768_-	phage replisome organiser	A0A0U2RT81	Escherichia_phage	1.1e-87	68.3
WP_000693816.1\|3394836_3395262_-	Rha family transcriptional regulator	NA	NA	NA	NA
WP_001261752.1\|3395258_3395486_-	cell division protein	NA	NA	NA	NA
WP_000444607.1\|3395583_3396228_+	LexA family transcriptional regulator	A0A1P8DTH0	Proteus_phage	2.8e-06	24.9
WP_000367376.1\|3396502_3396655_+	DUF1391 domain-containing protein	M4QQ57	Salicola_phage	8.7e-07	53.2
WP_000449168.1\|3397135_3397324_+	cell division inhibitor	NA	NA	NA	NA
WP_000199485.1\|3397320_3397509_+	DUF1482 family protein	NA	NA	NA	NA
WP_000034457.1\|3397604_3400076_+	exonuclease	A0A192Y6E0	Salmonella_phage	8.8e-56	56.6
WP_000094838.1\|3400134_3400338_+	DUF4224 domain-containing protein	NA	NA	NA	NA
WP_046671474.1\|3400337_3401372_+\|integrase	tyrosine-type recombinase/integrase	A0A192Y7M7	Salmonella_phage	2.1e-99	57.4
WP_001302302.1\|3401582_3402380_+	DgsA anti-repressor MtfA	NA	NA	NA	NA
WP_014714124.1\|3402869_3410852_+	inverse autotransporter adhesin-like protein YeeJ	NA	NA	NA	NA
WP_000480501.1\|3411113_3412166_-	glycosyltransferase family 9 protein	NA	NA	NA	NA
WP_000378596.1\|3412479_3413796_+	shikimate transporter	NA	NA	NA	NA
WP_001060244.1\|3413897_3415352_+	AMP nucleosidase	NA	NA	NA	NA
WP_000532909.1\|3415694_3416411_+	YebC/PmpR family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_122989775.1\|3417036_3418680_-	toxic metabolite efflux MATE transporter YeeO	NA	NA	NA	NA
WP_001011000.1\|3418797_3419748_-	HTH-type transcriptional regulator Cbl	NA	NA	NA	NA
WP_001011474.1\|3419849_3420767_-	nitrogen assimilation transcriptional regulator	NA	NA	NA	NA
WP_000986334.1\|3421223_3422159_-	L,D-transpeptidase	NA	NA	NA	NA
WP_001193830.1\|3422220_3423300_-	nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase	NA	NA	NA	NA
WP_001295633.1\|3423311_3424055_-	adenosylcobinamide-GDP ribazoletransferase	NA	NA	NA	NA
WP_000973176.1\|3424051_3424597_-	bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase	NA	NA	NA	NA
WP_001171554.1\|3424958_3425339_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZBP6	Stx2-converting_phage	1.4e-66	100.0
WP_000612591.1\|3425335_3425683_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	2.2e-61	100.0
WP_000998048.1\|3425732_3427271_+\|transposase	IS66-like element ISEc8 family transposase	A0A0P0ZBS5	Stx2-converting_phage	1.5e-300	100.0
3431616:3431631	attR	NA	NA	NA	NA

DBSCAN-SWA_12

3529150 : 3630093

109

Enterobacteria_phage(50.7%)

holin,integrase,terminase,tRNA,tail,portal,protease

attL 3582651:3582671|attR 3627599:3627619

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000476014.1\|3529150_3530512_+\|tRNA	tRNA 5-hydroxyuridine modification protein YegQ	Q6DW11	Phage_TP	1.9e-217	99.7
WP_001303579.1\|3530841_3531159_-	hypothetical protein	NA	NA	NA	NA
WP_000807362.1\|3531564_3532464_+	lipid kinase YegS	A0A1V0SBJ0	Catovirus	1.3e-12	29.0
WP_000178551.1\|3532545_3533325_-	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
WP_000844219.1\|3533424_3534465_-	galactitol-1-phosphate 5-dehydrogenase	NA	NA	NA	NA
WP_000490697.1\|3534512_3535868_-	galactitol permease IIC component	NA	NA	NA	NA
WP_000823288.1\|3535871_3536156_-	PTS galactitol transporter subunit IIB	NA	NA	NA	NA
WP_000182899.1\|3536186_3536639_-	PTS galactitol transporter subunit IIA	NA	NA	NA	NA
WP_000853846.1\|3536648_3537911_-	tagatose-bisphosphate aldolase subunit GatZ	NA	NA	NA	NA
WP_001301486.1\|3537939_3538794_-	tagatose-bisphosphate aldolase subunit GatY	NA	NA	NA	NA
WP_000129551.1\|3539092_3540145_-	class I fructose-bisphosphate aldolase	NA	NA	NA	NA
WP_024177454.1\|3540401_3541679_+	MFS transporter	NA	NA	NA	NA
WP_000846238.1\|3541675_3542680_+	ADP-ribosylglycohydrolase family protein	A0A1S6UB21	Serratia_phage	4.9e-13	29.4
WP_000011970.1\|3542676_3543642_+	kinase	NA	NA	NA	NA
WP_000434038.1\|3543615_3544362_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_001301907.1\|3544413_3545232_-	glycosyl hydrolase 25 family protein	D0R7H8	Paenibacillus_phage	4.2e-23	37.6
WP_000822268.1\|3545296_3546097_-	bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase	NA	NA	NA	NA
WP_001195634.1\|3546093_3546882_-	hydroxyethylthiazole kinase	NA	NA	NA	NA
WP_000141034.1\|3547215_3547455_+	hypothetical protein	NA	NA	NA	NA
WP_000836936.1\|3548505_3548853_+	hypothetical protein	NA	NA	NA	NA
WP_000735648.1\|3548862_3549177_+	outer membrane protein	NA	NA	NA	NA
WP_000019944.1\|3549286_3549559_-	Ni(II)/Co(II)-binding transcriptional repressor RcnR	NA	NA	NA	NA
WP_000134629.1\|3549679_3550531_+	nickel/cobalt efflux protein RcnA	NA	NA	NA	NA
WP_000153070.1\|3550748_3551087_+	Ni(II)/Co(II) efflux transporter accessory subunit RcnB	NA	NA	NA	NA
WP_001301545.1\|3551168_3552203_-	fimbrial protein	NA	NA	NA	NA
WP_000945390.1\|3552213_3554694_-	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_000677409.1\|3554709_3555384_-	fimbria/pilus periplasmic chaperone	NA	NA	NA	NA
WP_000682830.1\|3555471_3556014_-	fimbrial protein	NA	NA	NA	NA
WP_010904812.1\|3556305_3556587_-	DUF2574 family protein	NA	NA	NA	NA
WP_001005448.1\|3556848_3557958_-	iron-sulfur cluster carrier protein ApbC	NA	NA	NA	NA
WP_001301615.1\|3558089_3560123_+\|tRNA	methionine--tRNA ligase	A0A1V0SDF2	Indivirus	1.4e-54	27.6
WP_001411921.1\|3564085_3565366_+	WGR domain-containing protein	NA	NA	NA	NA
WP_000356841.1\|3567079_3570709_+	DUF4132 domain-containing protein	NA	NA	NA	NA
WP_000636932.1\|3570770_3571088_+	hypothetical protein	NA	NA	NA	NA
WP_001302026.1\|3572328_3573417_+	MoxR family ATPase	NA	NA	NA	NA
WP_001294377.1\|3573427_3574957_+	hypothetical protein	NA	NA	NA	NA
WP_000528951.1\|3574975_3575707_+	hypothetical protein	NA	NA	NA	NA
WP_001302810.1\|3575699_3576836_+	VWA domain-containing protein	Q9EYF7	Enterobacteria_phage	1.9e-167	100.0
WP_001087225.1\|3576832_3578836_+	hypothetical protein	Q9EYF6	Enterobacteria_phage	0.0e+00	100.0
WP_001295429.1\|3578960_3579422_+	YehR family lipoprotein	Q9EYF5	Enterobacteria_phage	1.9e-76	100.0
WP_001295430.1\|3579463_3579934_-	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	1.8e-82	100.0
WP_000598641.1\|3579980_3580700_-	two-component system response regulator BtsR	NA	NA	NA	NA
WP_001301761.1\|3580696_3582382_-	two-component regulatory system sensor histidine kinase BtsS	Q9EYF3	Enterobacteria_phage	1.7e-305	100.0
3582651:3582671	attL	NA	NA	NA	NA
WP_001261939.1\|3582896_3583145_+	DNA damage-inducible protein DinI	B6DZC1	Enterobacteria_phage	1.4e-38	100.0
WP_001143784.1\|3583306_3583948_-	DUF1076 domain-containing protein	B6DZC0	Enterobacteria_phage	6.8e-109	100.0
WP_072142879.1\|3584029_3584446_-	DUF1076 domain-containing protein	B6DZB9	Enterobacteria_phage	2.2e-76	100.0
WP_001023396.1\|3584606_3584876_-\|tail	phage tail protein	B6DZB8	Enterobacteria_phage	3.8e-45	100.0
WP_088136427.1\|3584877_3586047_-\|tail	phage tail protein	B6DZB7	Enterobacteria_phage	1.1e-83	99.5
WP_001230508.1\|3586111_3586711_-	outer membrane protein	A0A0P0ZE39	Stx2-converting_phage	1.2e-110	100.0
WP_137049505.1\|3586778_3590189_-	host specificity protein J	B6DZB5	Enterobacteria_phage	0.0e+00	99.6
WP_050546863.1\|3590492_3591125_-\|tail	tail assembly protein	A0A0P0ZC16	Stx2-converting_phage	5.8e-105	99.5
WP_024748514.1\|3591070_3591814_-\|tail	phage tail protein	Q6H9T4	Enterobacteria_phage	6.1e-146	96.4
WP_001416783.1\|3591824_3592523_-\|tail	phage minor tail protein L	A0A0P0ZBE3	Stx2-converting_phage	3.1e-131	98.3
WP_000847298.1\|3592522_3592852_-\|tail	phage tail protein	Q687F2	Enterobacteria_phage	4.3e-59	100.0
WP_000532073.1\|3595537_3595846_-\|tail	phage tail assembly protein T	Q687F4	Enterobacteria_phage	1.3e-54	100.0
WP_000479062.1\|3595872_3596295_-\|tail	phage minor tail protein G	Q687F5	Enterobacteria_phage	2.2e-71	97.9
WP_024748478.1\|3596308_3597061_-\|tail	phage tail protein	Q687F6	Enterobacteria_phage	2.9e-135	99.6
WP_000682716.1\|3597068_3597467_-\|tail	tail protein	Q9EYD7	Enterobacteria_phage	5.9e-71	100.0
WP_000974966.1\|3597479_3598103_-	hypothetical protein	Q9EYD6	Enterobacteria_phage	6.6e-101	100.0
WP_001281350.1\|3598105_3598387_-	DNA breaking-rejoining protein	Q8VNN4	Enterobacteria_phage	3.9e-45	97.8
WP_001097065.1\|3598379_3598706_-	DUF2190 family protein	Q9EYD5	Enterobacteria_phage	6.1e-50	100.0
WP_001114421.1\|3598793_3600818_-\|protease	Clp protease ClpP	S5M7Q8	Escherichia_phage	0.0e+00	99.7
WP_000974568.1\|3600762_3602265_-\|portal	phage portal protein	S5MW34	Escherichia_phage	6.3e-291	100.0
WP_000102415.1\|3602264_3602477_-	hypothetical protein	S5MBY8	Escherichia_phage	3.0e-29	98.6
WP_001077626.1\|3602473_3604597_-\|terminase	phage terminase large subunit family protein	S5MDQ1	Escherichia_phage	0.0e+00	99.0
WP_000348565.1\|3604593_3605070_-	DUF1441 family protein	Q9EYD0	Enterobacteria_phage	2.1e-83	100.0
WP_012816791.1\|3605587_3605773_-	membrane protein	A0A0P0ZCT3	Stx2-converting_phage	1.2e-18	100.0
WP_000539792.1\|3606000_3606147_-	hypothetical protein	A0A0P0ZE99	Stx2-converting_phage	2.6e-16	100.0
WP_001056806.1\|3606146_3606716_-	hypothetical protein	A0A1I9LJR6	Stx_converting_phage	3.1e-105	100.0
WP_000087728.1\|3606986_3607520_-	lysozyme	A0A1I9LJR4	Stx_converting_phage	1.8e-102	100.0
WP_000284506.1\|3607524_3607740_-\|holin	holin	Q9ZWW2	Enterobacteria_phage	6.9e-34	100.0
WP_001290230.1\|3607817_3608063_-	DUF826 domain-containing protein	A0A0P0ZGR2	Escherichia_phage	8.8e-17	100.0
WP_000143458.1\|3608103_3608283_-	DUF1378 family protein	A0A2R2Z345	Escherichia_phage	2.2e-25	100.0
WP_001356551.1\|3611171_3611324_-	DNA methylase	A0A2R2Z327	Escherichia_phage	4.0e-20	100.0
WP_001204769.1\|3611572_3612007_-	antitermination protein	G9L695	Escherichia_phage	1.3e-79	97.2
WP_000971055.1\|3612092_3612233_-	YlcG family protein	K7PHH3	Enterobacteria_phage	1.1e-08	69.8
WP_001099712.1\|3612229_3612592_-	crossover junction endodeoxyribonuclease RusA	K7PM48	Enterobacteria_phage	4.3e-60	96.5
WP_000774504.1\|3612588_3612879_-	DUF1364 domain-containing protein	K7PGZ6	Enterobacteria_phage	2.8e-46	92.7
WP_000224907.1\|3612871_3613042_-	hypothetical protein	K7P7K0	Enterobacteria_phage	5.3e-13	67.9
WP_001053021.1\|3613041_3613497_-	DNA base-flipping protein YbcN	I6PD71	Cronobacter_phage	5.9e-59	66.2
WP_072141214.1\|3613493_3613595_-	hypothetical protein	NA	NA	NA	NA
WP_000390541.1\|3613685_3613967_-	hypothetical protein	NA	NA	NA	NA
WP_001481254.1\|3614010_3614208_-	hypothetical protein	NA	NA	NA	NA
WP_000145928.1\|3614435_3614720_-	hypothetical protein	A0A0P0ZCJ0	Stx2-converting_phage	3.7e-43	96.7
WP_000788906.1\|3614716_3615418_-	Replication protein 14	Q9EYB6	Enterobacteria_phage	5.8e-130	100.0
WP_001417283.1\|3615414_3616344_-	replication protein	A0A0M5M7Y1	Salmonella_phage	8.9e-110	63.8
WP_001182876.1\|3616430_3616970_-	hypothetical protein	M9NZI6	Enterobacteria_phage	2.6e-61	66.1
WP_000712399.1\|3617333_3618026_+	helix-turn-helix transcriptional regulator	Q76H56	Enterobacteria_phage	2.5e-109	86.1
WP_001362421.1\|3618132_3619740_+	hypothetical protein	A0A1S5SA14	Streptococcus_phage	6.9e-94	49.0
WP_023148105.1\|3620243_3620534_+	hypothetical protein	K7P6H3	Enterobacteria_phage	5.0e-27	85.1
WP_000995395.1\|3620609_3620906_+	host-nuclease inhibitor protein Gam	Q9EYA6	Enterobacteria_phage	4.3e-50	100.0
WP_000100847.1\|3620911_3621697_+	phage recombination protein Bet	A0A1I9LJN0	Stx_converting_phage	6.3e-149	100.0
WP_000186740.1\|3621693_3622371_+	YqaJ viral recombinase family protein	A0A1I9LJM9	Stx_converting_phage	4.6e-132	100.0
WP_032195523.1\|3622370_3622553_+	DUF1317 domain-containing protein	A0A0P0ZAS9	Stx2-converting_phage	1.6e-28	98.3
WP_000548547.1\|3622525_3622717_+	DUF1382 family protein	A0A1I9LJM8	Stx_converting_phage	1.9e-27	100.0
WP_001444000.1\|3622727_3623009_+	cell division protein ZapA	A0A0P0ZBQ0	Stx2-converting_phage	1.9e-47	100.0
WP_000763383.1\|3623107_3623329_+	TraR/DksA family transcriptional regulator	A0A1I9LJM6	Stx_converting_phage	2.9e-35	100.0
WP_001289954.1\|3623325_3624273_+	ead/Ea22-like family protein	A0A0P0ZE96	Stx2-converting_phage	3.6e-183	100.0
WP_001356547.1\|3624274_3624451_+	hypothetical protein	B6DZ55	Enterobacteria_phage	4.6e-28	100.0
WP_000207903.1\|3624784_3625141_+	hypothetical protein	A0A0N7KZJ2	Stx2-converting_phage	3.1e-63	100.0
WP_000610375.1\|3625137_3625500_+	DUF551 domain-containing protein	Q9EY98	Enterobacteria_phage	1.8e-71	100.0
WP_000457728.1\|3625587_3625830_+	DUF4222 domain-containing protein	B6DZ51	Enterobacteria_phage	1.5e-37	100.0
WP_000556583.1\|3625833_3625968_+	hypothetical protein	A0A0P0ZDP5	Stx2-converting_phage	4.9e-22	100.0
WP_001193437.1\|3625986_3626241_+	excisionase	Q859D3	Escherichia_coli_phage	3.0e-44	100.0
WP_000063648.1\|3626274_3627561_+\|integrase	site-specific integrase	Q9EY96	Enterobacteria_phage	7.6e-253	100.0
WP_027868261.1\|3627581_3628283_+	HTH-type transcriptional regulator MlrA	Q9EYF2	Enterobacteria_phage	4.6e-103	100.0
3627599:3627619	attR	NA	NA	NA	NA
WP_001216963.1\|3628342_3628450_+	protein YohO	NA	NA	NA	NA
WP_000783120.1\|3628430_3629162_-	glycine betaine ABC transporter permease YehW	NA	NA	NA	NA
WP_000569336.1\|3629166_3630093_-	glycine betaine ABC transporter ATP binding protein YehX	G3M9Y6	Bacillus_virus	4.8e-23	30.8

DBSCAN-SWA_13

3874374 : 3879761

Enterobacteria_phage(50.0%)

integrase

attL 3864825:3864841|attR 3876789:3876805

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3864825:3864841	attL	NA	NA	NA	NA
WP_000368131.1\|3874374_3875307_+	transporter	E7DYY8	Enterobacteria_phage	1.2e-167	100.0
WP_000958700.1\|3875618_3876776_+\|integrase	prophage integrase IntS	E7DYQ6	Enterobacteria_phage	2.2e-222	100.0
WP_153038089.1\|3876950_3878087_-	acyltransferase	Q716G3	Shigella_phage	9.0e-80	72.4
3876789:3876805	attR	NA	NA	NA	NA
WP_000960724.1\|3878096_3878777_-	DNA transfer protein	G5DA80	Enterobacteria_phage	1.8e-59	71.0
WP_000403517.1\|3878763_3879231_-	DUF2824 family protein	Q2A0B3	Sodalis_phage	1.7e-64	74.7
WP_001005794.1\|3879230_3879761_-	hypothetical protein	Q716G6	Shigella_phage	5.7e-69	99.3

DBSCAN-SWA_14

4121480 : 4180970

Enterobacteria_phage(31.58%)

holin,integrase,tRNA,transposase,tail

attL 4138928:4138942|attR 4185929:4185943

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000997403.1\|4121480_4122518_-\|tRNA	tRNA/rRNA methyltransferase	NA	NA	NA	NA
WP_001098726.1\|4122724_4123144_+	thioredoxin TrxC	A0A0K2FIM3	Achromobacter_phage	2.8e-15	38.5
WP_000138184.1\|4123212_4123911_+	DTW domain-containing protein	NA	NA	NA	NA
WP_000082974.1\|4123942_4126603_+	protein lysine acetyltransferase	NA	NA	NA	NA
WP_000949265.1\|4126716_4128072_+	CDP-diacylglycerol--serine O-phosphatidyltransferase	NA	NA	NA	NA
WP_001322343.1\|4128117_4128441_+	YfiM family lipoprotein	NA	NA	NA	NA
WP_000852126.1\|4128437_4129736_-	alpha-ketoglutarate permease	Q6JIH2	Burkholderia_virus	7.4e-46	32.2
WP_001235102.1\|4135511_4138085_-	ATP-dependent chaperone ClpB	H6X3M6	Enterobacteria_phage	2.6e-127	35.3
WP_000040152.1\|4138214_4138946_-	polyphenol oxidase	NA	NA	NA	NA
4138928:4138942	attL	NA	NA	NA	NA
WP_000079092.1\|4138942_4139923_-	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	NA	NA	NA	NA
WP_000197686.1\|4140057_4140795_+	outer membrane protein assembly factor BamD	NA	NA	NA	NA
WP_000178456.1\|4141065_4141407_+	ribosome-associated translation inhibitor RaiA	NA	NA	NA	NA
WP_001386991.1\|4141510_4141558_+	hypothetical protein	NA	NA	NA	NA
WP_000200120.1\|4141656_4142817_+	bifunctional chorismate mutase/prephenate dehydratase	NA	NA	NA	NA
WP_000225204.1\|4142859_4143981_-	bifunctional chorismate mutase/prephenate dehydrogenase	NA	NA	NA	NA
WP_001168032.1\|4143991_4145062_-	3-deoxy-7-phosphoheptulonate synthase AroF	A0A0F6R6T6	Escherichia_coli_O157_typing_phage	6.9e-90	51.2
WP_001301878.1\|4145271_4145637_+	DUF2799 domain-containing protein	NA	NA	NA	NA
WP_001212391.1\|4145786_4146305_+	DUF4154 domain-containing protein	NA	NA	NA	NA
WP_000969012.1\|4146294_4147521_+	diguanylate cyclase DgcN	NA	NA	NA	NA
WP_000589828.1\|4147536_4148019_+	OmpA family protein	NA	NA	NA	NA
WP_000065253.1\|4148095_4148443_-	50S ribosomal protein L19	NA	NA	NA	NA
WP_000264777.1\|4148484_4149252_-\|tRNA	tRNA (guanosine(37)-N1)-methyltransferase TrmD	NA	NA	NA	NA
WP_000043335.1\|4149282_4149831_-	ribosome maturation factor RimM	NA	NA	NA	NA
WP_000256450.1\|4149849_4150098_-	30S ribosomal protein S16	NA	NA	NA	NA
WP_000460035.1\|4150234_4151596_-	signal recognition particle protein	NA	NA	NA	NA
WP_001338897.1\|4151762_4152554_+	inner membrane protein YpjD	NA	NA	NA	NA
WP_077626229.1\|4152575_4153862_+	HlyC/CorC family transporter	NA	NA	NA	NA
WP_001296310.1\|4153916_4154510_-	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_001059175.1\|4154632_4155511_+	NAD(+) kinase	NA	NA	NA	NA
WP_000880924.1\|4155596_4157258_+	DNA repair protein RecN	NA	NA	NA	NA
WP_001203437.1\|4157406_4157748_+	outer membrane protein assembly factor BamE	NA	NA	NA	NA
WP_001117844.1\|4157809_4158100_-	RnfH family protein	NA	NA	NA	NA
WP_000600190.1\|4158089_4158566_-	type II toxin-antitoxin system toxin RatA	NA	NA	NA	NA
WP_000162574.1\|4158697_4159180_+	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	4.0e-29	46.8
WP_001217542.1\|4160025_4160274_+	DNA damage-inducible protein DinI	A5LH55	Enterobacteria_phage	3.1e-38	98.8
WP_001132157.1\|4160775_4161366_-	T3SS effector guanine nucleotide exchange factor EspM2	NA	NA	NA	NA
WP_001144077.1\|4161548_4162199_+	DUF1076 domain-containing protein	B6DZZ5	Stx2-converting_phage	2.8e-25	37.2
WP_001301665.1\|4162277_4163336_+	T3SS effector EspW	NA	NA	NA	NA
WP_000442132.1\|4163465_4163888_-	DUF1076 domain-containing protein	B6DZB9	Enterobacteria_phage	5.7e-72	97.0
WP_001023396.1\|4164048_4164318_-\|tail	phage tail protein	B6DZB8	Enterobacteria_phage	3.8e-45	100.0
WP_001303014.1\|4164319_4164886_-\|transposase	transposase	A0A0P0ZBS5	Stx2-converting_phage	7.9e-69	99.3
WP_000612591.1\|4164935_4165283_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	2.2e-61	100.0
WP_001171554.1\|4165279_4165660_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZBP6	Stx2-converting_phage	1.4e-66	100.0
WP_000731241.1\|4166016_4166361_-	YdfR family protein	A0A0P0ZD64	Stx2-converting_phage	1.7e-58	99.1
WP_000284517.1\|4166365_4166581_-\|holin	holin	A0A0P0ZC45	Stx2-converting_phage	4.5e-33	98.6
WP_000143065.1\|4166730_4168584_-	DUF1737 domain-containing protein	H6WZJ9	Escherichia_phage	0.0e+00	97.9
WP_000499458.1\|4168991_4169159_-	DUF3927 domain-containing protein	NA	NA	NA	NA
WP_001302581.1\|4169244_4169988_-	hypothetical protein	NA	NA	NA	NA
WP_001235472.1\|4170240_4170864_-	antitermination protein	K7PM87	Enterobacteria_phage	2.2e-112	98.1
WP_001028854.1\|4170860_4171526_-	serine/threonine protein phosphatase	Q5TJL8	Enterobacteria_phage	5.0e-131	99.5
WP_001223948.1\|4171522_4172134_-	protein ninG	A0A1U9AJF8	Stx1_converting_phage	2.5e-92	95.6
WP_001108081.1\|4172108_4172675_-	HNH endonuclease	A0A1U9AJK5	Stx1_converting_phage	2.3e-108	100.0
WP_001254939.1\|4173046_4173802_+\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_001417601.1\|4173837_4174140_+	outer membrane protein assembly factor BamE	NA	NA	NA	NA
WP_064234917.1\|4174215_4175502_-	hypothetical protein	NA	NA	NA	NA
WP_000361847.1\|4175897_4176311_-	hypothetical protein	NA	NA	NA	NA
WP_001052051.1\|4176408_4176807_-	hypothetical protein	NA	NA	NA	NA
WP_000428092.1\|4178449_4179763_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_000540864.1\|4179764_4180970_-\|integrase	site-specific integrase	NA	NA	NA	NA
4185929:4185943	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr_ID: NZ_CP040309.1|WP_001302977.1|2266511_2266697_-|DUF3950-domain-containing-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_CP040309.1|WP_001302977.1|2266511_2266697_-|DUF3950-domain-containing-protein

2266511_2266697_-

61 aa aa

2243915-2364465

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP040309_4	Orphan	4.2\|3615951\|26\|NZ_CP040309\|PILER-CR	3615951-3615976	26	2322313-2322288	0

1. spacer 4.2|3615951|26|NZ_CP040309|PILER-CR matches to NZ_CP040309 position: 2322313-2322288, mismatch: 0

atttacctctttcaggtaaactttat	CRISPR spacer
atttacctctttcaggtaaactttat	Protospacer
**************************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP040310

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP040309

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information