CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP033116	Pseudomonas pelagia strain Kongs-67 chromosome, complete genome	2 crisprs	csa3,cas3,DEDDh,DinG,WYL	0	0	8	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP033116_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP033116_1

2949288-2949394

Orphan

Consensus_repeat	Method
CAGGATGTCCTGGCCGTCACCGCCAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP033116_1

>merge|NZ_CP033116|1|2949288-2949394|CRISPRCasFinder
CAGGATGTCCTGGCCGTCACCGCCAAGGAGGAAGTCATCGCCCTCGCCGGCGCGAATCTCCGAGCCGTCCGGCCCGGTGATCAGGAAGTCCTGGCCGTCACCGCCAA

>NZ_CP033116|1|1|2949288-2949394|CRISPRCasFinder
CAGGATGTCCTGGCCGTCACCGCCAA	GGAGGAAGTCATCGCCCTCGCCGGCGCGAATCTCCGAGCCGTCCGGCCCGGTGAT
CAGGAAGTCCTGGCCGTCACCGCCAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP033116.1\|WP_096348108.1\|2961473_2962325_-\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|224098
NZ_CP033116.1\|WP_096348109.1\|2959641_2960607_-\|amidohydrolase	unknown	unknown	gnl\|CDD\|368185
NZ_CP033116.1\|WP_096348121.1\|2939568_2940156_-\|adhesin	unknown	unknown	unknown
NZ_CP033116.1\|WP_096348118.1\|2942480_2944499_-\|calcium-binding-protein	unknown	unknown	gnl\|CDD\|380205
NZ_CP033116.1\|WP_096348114.1\|2954351_2955053_-\|NrdJb	unknown	unknown	gnl\|CDD\|236330
NZ_CP033116.1\|WP_096348119.1\|2941142_2942471_-\|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|130902
NZ_CP033116.1\|WP_096348124.1\|2937212_2937944_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP033116.1\|WP_096348117.1\|2944495_2946244_-\|type-I-secretion-system-permease/ATPase	unknown	unknown	gnl\|CDD\|226969
NZ_CP033116.1\|WP_096348112.1\|2957537_2958122_-\|DUF1285-domain-containing-protein	unknown	unknown	gnl\|CDD\|377736
NZ_CP033116.1\|WP_096348143.1\|2960749_2961388_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP033116.1\|WP_096348107.1\|2962321_2963200_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224097
NZ_CP033116.1\|WP_096348122.1\|2938755_2939514_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP033116.1\|WP_096348111.1\|2958132_2958729_-\|DUF4823-domain-containing-protein	unknown	unknown	gnl\|CDD\|374367
NZ_CP033116.1\|WP_096348144.1\|2935885_2937142_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|179798
NZ_CP033116.1\|WP_096348125.1\|2934529_2935861_+\|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225114
NZ_CP033116.1\|WP_096348110.1\|2958751_2959642_-\|B12-binding-domain-containing-radical-SAM-protein	unknown	unknown	gnl\|CDD\|214792
NZ_CP033116.1\|WP_096348113.1\|2955135_2957289_-\|adenosylcobalamin-dependent-ribonucleoside-diphosphate-reductase	unknown	unknown	gnl\|CDD\|274168
NZ_CP033116.1\|WP_096348115.1\|2953185_2954067_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|197666
NZ_CP033116.1\|WP_096348123.1\|2937982_2938681_-\|C39-family-peptidase	unknown	unknown	gnl\|CDD\|239103
NZ_CP033116.1\|WP_096348120.1\|2940157_2940568_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP033116.1\|WP_096348109.1\|2959641_2960607_-\|amidohydrolase	gnl\|CDD\|368185	pfam04909, Amidohydro_2, Amidohydrolase. These proteins are amidohydrolases that are related to pfam01979.	7.25601e-17
NZ_CP033116.1\|WP_096348114.1\|2954351_2955053_-\|NrdJb	gnl\|CDD\|236330	PRK08665, PRK08665, vitamin B12-dependent ribonucleotide reductase.	1.39198e-08
NZ_CP033116.1\|WP_096348118.1\|2942480_2944499_-\|calcium-binding-protein	gnl\|CDD\|380205	NF033203, entero_EhxA, enterohemolysin EhxA. Members of this family are the RTX toxin called enterohemolysin or EhxA, because it is found in enterohemorrhagic Escherichia coli (EHEC) strains such as O157:H7.	8.63499e-30
NZ_CP033116.1\|WP_096348119.1\|2941142_2942471_-\|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit	gnl\|CDD\|130902	TIGR01843, Hemolysin_secretion_protein_D_plasmid, type I secretion membrane fusion protein, HlyD family. Type I secretion is an ABC transport process that exports proteins, without cleavage of any signal sequence, from the cytosol to extracellular medium across both inner and outer membranes. The secretion signal is found in the C-terminus of the transported protein. This model represents the adaptor protein between the ATP-binding cassette (ABC) protein of the inner membrane and the outer membrane protein, and is called the membrane fusion protein. This model selects a subfamily closely related to HlyD; it is defined narrowly and excludes, for example, colicin V secretion protein CvaA and multidrug efflux proteins. [Protein fate, Protein and peptide secretion and trafficking].	4.08659e-105
NZ_CP033116.1\|WP_096348117.1\|2944495_2946244_-\|type-I-secretion-system-permease/ATPase	gnl\|CDD\|226969	COG4618, ArpD, ABC-type protease/lipase transport system, ATPase and permease components [General function prediction only].	0
NZ_CP033116.1\|WP_096348112.1\|2957537_2958122_-\|DUF1285-domain-containing-protein	gnl\|CDD\|377736	pfam06938, DUF1285, Protein of unknown function (DUF1285). This family consists of several hypothetical bacterial proteins of around 200 residues in length. The function of this family is unknown. The structures revealed a conserved core with domain duplication and a superficial similarity of the C-terminal domain to pleckstrin homology-like folds. The conservation of the domain- interface indicates a potential binding site that is likely to involve a nucleotide-based ligand, with genome-context and gene-fusion analyses additionally supporting a role for this family in signal transduction, possibly during oxidative stress.	4.98376e-86
NZ_CP033116.1\|WP_096348143.1\|2960749_2961388_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	5.95638e-16
NZ_CP033116.1\|WP_096348107.1\|2962321_2963200_-\|ABC-transporter-permease	gnl\|CDD\|224097	COG1176, PotB, ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism].	1.38673e-67
NZ_CP033116.1\|WP_096348110.1\|2958751_2959642_-\|B12-binding-domain-containing-radical-SAM-protein	gnl\|CDD\|214792	smart00729, Elp3, Elongator protein 3, MiaB family, Radical SAM. This superfamily contains MoaA, NifB, PqqE, coproporphyrinogen III oxidase, biotin synthase and MiaB families, and includes a representative in the eukaryotic elongator subunit, Elp-3. Some members of the family are methyltransferases.	1.78496e-26
NZ_CP033116.1\|WP_096348123.1\|2937982_2938681_-\|C39-family-peptidase	gnl\|CDD\|239103	cd02423, Peptidase_C39G, A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic). The cleavage is mediated by the transporter as part of the secretion process. Bacteriocins are antibiotic proteins secreted by some species of bacteria that inhibit the growth of other bacterial species. The bacteriocin is synthesized as a precursor with an N-terminal leader peptide, and processing involves removal of the leader peptide by cleavage at a Gly-Gly bond, followed by translocation of the mature bacteriocin across the cytoplasmic membrane. Most endopeptidases of family C39 are N-terminal domains in larger proteins (ABC transporters) that serve both functions. The proposed protease active site is conserved in this sub-family of proteins with a single peptidase domain, which are lacking the nucleotide-binding transporter signature.	1.43411e-54
NZ_CP033116.1\|WP_096348144.1\|2935885_2937142_-\|hypothetical-protein	gnl\|CDD\|179798	PRK04239, PRK04239, DNA-binding protein.	0.000982114
NZ_CP033116.1\|WP_096348125.1\|2934529_2935861_+\|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl\|CDD\|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	1.65175e-150
NZ_CP033116.1\|WP_096348108.1\|2961473_2962325_-\|ABC-transporter-permease-subunit	gnl\|CDD\|224098	COG1177, PotC, ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism].	3.10761e-51
NZ_CP033116.1\|WP_096348113.1\|2955135_2957289_-\|adenosylcobalamin-dependent-ribonucleoside-diphosphate-reductase	gnl\|CDD\|274168	TIGR02504, ribonucleotide_reductase, ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent. This model represents a group of adenosylcobalamin(B12)-dependent ribonucleotide reductases (Class II RNRs) related to the characterized species from Pyrococcus, Thermoplasma, Corynebacterium, and Deinococcus. RNR's are responsible for the conversion of the ribose sugar of RNA into the deoxyribose sugar of DNA. This is the rate-limiting step of DNA biosynthesis. This model identifies genes in a wide range of deeply branching bacteria. All are structurally related to the class I (non-heme iron dependent) RNRs. In most species this gene is known as NrdJ, while in mycobacteria it is called NrdZ. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism].	0
NZ_CP033116.1\|WP_096348115.1\|2953185_2954067_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	4.58141e-27
NZ_CP033116.1\|WP_096348111.1\|2958132_2958729_-\|DUF4823-domain-containing-protein	gnl\|CDD\|374367	pfam16105, DUF4823, Domain of unknown function (DUF4823). This family consists of hypothetical lipoproteins around 210 residues of length and is mainly found in various Pseudomonas species. The function of this family is unknown.	5.63127e-49

>NZ_CP033116.1|WP_096348117.1|2944495_2946244_-|type-I-secretion-system-permease/ATPase
MRKRDASTSSKRKSAEQLTKGFRGIFFFLFGMSGIINILALTGAFYMLQIYDRALTSGSLSTLLAISILALGLYCFQGIFDVIRSQILVRVGARLDKNIAPIAHRVAIDMPRFGFSTAESLERGRDVDTVRGFLGSQGPVALLDLPWMPLFLIFVYVLHPYLGALVFLGGLILAVLAIATELMTSKLSNSMQVAVITRNTIADSNARNAEILKAMGFAGRAVARFNRANADHLDLQTRTNDISGTLGAVARVLRMILQSAVLGLGAVLTIQGDLSAGAIIAASIASARALAPIDLAIGNWKSVVAARTAFARLKETVVALAEADEPMELPSPSSSLRVENITVAAPDSGQVLLSEVSFELKAGHAVGIIGPSGGGKTTLLRALTGIWPVLRGSVRLDDAELSQWHDEALGQLIGYLPQEIALLNGTIEENISRFQEKPDPRAVVAAAVAASVHEMIVRLPNGYQTQLGSLGASLSGGQRQRIGLARALFGNPFLVVLDEPNSNLDAEGEAALRAAIEGVRQRGGIAVVAAHRPSALAAVDLVGVVQNGRLAAFGLKDEIIGKSQVREVHPAKSPSKEALVKP
>NZ_CP033116.1|WP_096348118.1|2942480_2944499_-|calcium-binding-protein
MINVKGTKNASPETDTSQRYVQKSGDETSRTPHAISALLMGVTAYLTSIFAWGPERAPRPTPEEPIAAAVAPPSPEDMAEGMASSRKSHDLTDSEPPSSGTSSVDDAPRSTSLSYPGDSEGVLLAGRPTSGNSNAEIPDRGGRPADTSLANDDPALGGGGSSGAGSPPVDDLPADGADPTDGGDPTDDGESLDGDPLNPDIDDTDCVDRSDQNRAPRVSGPVYLLDVAPCTALLIALDDLLGKAYDPDGDVLWVENLVVSSGTLTEVDGGWVFQSDMGQLGPVTLTYQISDGELTTDAVARFSVVEQPVIVGTAANDTLLGSLCADEIDGADGDDNIDGRAGDDVLAGGAGDDHIVAGDGDDVVFGGDGNDIIFGGAGNDHLFGGDGDDRLFGDDGDDVIFGNAGEDRLSGGDGNDLLFGGDGADFLYGDAGDDTLAGGEGDDRLYGGAGQDVIDGGDGNDVIMDGAGRDQVFGGMGSDRVVAALDADDDVYDGGADSDTLDYSSAWEGIVVDLVNGVASGVEIGRDAITGFEKVLGGRGDDLFILGSEPVALTGGAGDDVFAFDIIGGDRPNAVSHVILDFGVGDRIRMSEYDIFSKADDDADDRFERIYQSNGDHDLPIRYRHDRDEGLDWTVIETDFEADEAWAAAITLQGTHTLLWSTERDDGLEWLS
>NZ_CP033116.1|WP_096348119.1|2941142_2942471_-|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit
MSTNGSSGGAGKPSPNPDNAFRLGPRVFVGAALALLLLVGVGGWAVSAQLSGAVIAQGFVTVDQDLKSIQHRDGGIVSEIAIREGDIVRAGDVLLRLQDTQTKAELSIVRSKLVELAIRRARLLAERDGLAAIEFPSDLNVEDSPDVFLGETRMFDGNRTSRESKKQQLELSVEQIKEEIKGLDAQRRSKGEEFQLVEAEYEANKGLVSKGIIARTLLVPLARDRVKLSGERGEIHASIARAKTRMSEIRVQIIAIDENARTEAQRELSSVEAEFSELRDRHIAIEDRLARTDIRAPISGTVNELNVHTIGGVITPAEELVTIVPEDAKLKVEVKLVPISIDQLWVGQAVRLRFTAFNQRTTPELKGELIYVSAATTRDDTTGESYYLGDVNVPAQELQKLGNVTLLPGMPVEVFITTEERTAMTYFIKPVTDQFSRAFREE
>NZ_CP033116.1|WP_096348120.1|2940157_2940568_-|hypothetical-protein
MIAPTSLLAAGGDILLSREVQPRAATREPLVPDPNPRVVNPKPSTYVGEDLQMGSVPGELNDGDFAAVTSGARMTQQLLSPTAQGVHSATSRLGNPSSVAGNNPVGHAGGSLGKIDSNVNRSIQQGLRPLQILQRQ
>NZ_CP033116.1|WP_096348121.1|2939568_2940156_-|adhesin
MNSANLVVAVAIASLLGSAAALGEMSANADIQSSGKGYNGVVMINQAAGDGQQQVNVRALAAGDNAQARIKVEQIRETIVEEQVQLDASVRIGAGAFSQGDGVLGINQSAGIGTQQINAFRIEVGSMPQSLDDSGLAQSVAPSSINSGAVAPQSGQRQVSIDDQAFADSRGVVQLNQSAGVGNRMVNNLGIRIMD
>NZ_CP033116.1|WP_096348122.1|2938755_2939514_-|hypothetical-protein
MKTQKLLTPLALAMVAMLSVGAHASGSGASADIVDAQNNEGNNAVNDTVENTAVVDGSLGGASGNVGVNVAAGDNNQQANAAAIATADTAFVFGIGVGASAQASIDVDQTNHHNEVENHGVPNNAALNNSANGTSGNVGVNIAAGNSNQQKNDMSVASSETAYTASAYVNVYQDSHDNLVSNESLGGSHGGYGYGYGGGGNQSGVAVINNAVLSGSLNGVSGNVGANIAAGSGNQQSNSLAIAAGCTACPNL
>NZ_CP033116.1|WP_096348123.1|2937982_2938681_-|C39-family-peptidase
MKGISLAIVLALLAAPLNPVQAQTASKPFAALPNGALIYKPVTSMRERRFINLVEQQTDFSCGAAALATVLNQAYGWEFTEADVIQGMLAEADMELVRTQGFSMLDMKRFAETIGLRARGYRIPPEQLEQVKVPAIVLIDVRGYKHFVVMQTSSDGWVYIGDPVLGHKKMTLEDFTQGWNGIIFAVIGPGYDRDNALLSPPEPLTAKHRLDRFRPVPDAELLDFGFIQSDFF
>NZ_CP033116.1|WP_096348124.1|2937212_2937944_-|hypothetical-protein
MNRKHWWVVGVISLSLPVNAASLFQPVEISDAELSQLRGRYVLPDRVIHFGVTMSTFWQNNAGQSIGANVTLQVRGQAQPSLHVSYVGQAESGGSAAVPGVGQVIGGNGLAQVQGISQSVRSAGDYNDALNDLSISISNTVESLPTPEGQAWSGSTQFSNEAGSVQITNQAGGLRLALDANGQGLAQQQIGGGNVLQQANINSSLNSVRNLAALNIALRDRPLNMDLANCTWEQLRALRPAGY
>NZ_CP033116.1|WP_096348144.1|2935885_2937142_-|hypothetical-protein
MIGVSSVAFAQPEEVDLRRQLEELQKRYEAQQNALMILEQRIRQVEGRRAEAVAEANQRNVPVSPPTQTAQSTQSSQSSQPTQTARAGSGYGESLKDSSEPAPSVEALYQEASGFFGSGTFSLEPGITYSHYDTRQLFLNGFLALDAIFLGNLGIDEINADTFTFDLTGRYNWRQRWQFDANIPVVYRQTTYQSAGAGGSSAQFSEEKVTGDPRLGDISVGLAYKFLDESPGIPDAVASLRVRMPTGKDPYGIKLDTVPGNDNLSVPEDLPTGNGVWSVTPGISLVKTVDPAVLFGNLSYTYHLEGDFSDISPQIGVKVPGKVQLGNYFQLGVGMAFALNERMSMSMSFSELISRSSRIRPDGGGWQTVNGSDVNAAYFNLGATFAATDRLTVVPSLAIGLTPDAPDFSVSVKFPYYY
>NZ_CP033116.1|WP_096348125.1|2934529_2935861_+|sigma-54-dependent-Fis-family-transcriptional-regulator
MLDKIDTGARKLLVVETFAEWSCLLNNLTQTGWRIVNTSLNHAAGKECDVGVIHLLDSHLQQQEMLKRVIRQSGGEWIAVIDQDVKDKTAMRSFISEWFFDFYTLPFDFQRMQAALGRAYGMSRLRNLTRHFALKEDHEFLGTSAQAKTLRKLVTRCATTDSPVLIRGESGTGKELVARALHWKSRRADKPFVAVNCGAIPDQLIQSEMFGHEKGAFTGAHQRKIGRIEAANGGTLFLDEIGDLPLELQANMLRFLQEMQIERVGSTQPIQVDVRVVAATHIDLEAAIVEGRFREDLYYRLNVLEIRTAPLRDRHADIPILAQHFAQLYAGEVGRKPRPFSEATINAMLQHGWPGNVRELANRVRRGMVLAEGRTIEPSDLGLTAVQERVKVAERLENYILRAEKQALQDALTLNPGNMCRVAETLGISRPTLYRMLHRHQII
>NZ_CP033116.1|WP_096348115.1|2953185_2954067_+|helix-turn-helix-domain-containing-protein
MQPKEYVLIIVRNIQNRVDNDFHHALRQAGYRVEIVPSGQDPVPLMQAHPPVAACFQFDYPDFEGLASLRETKTAMPSVPLLMITQAHSESLAVWAFRARVWDYFVQPIDIPRLMEVAAKLYRLHLPQKSRPPRHDAAQIRNQIPPEARTHCSTLLDDQALLQRIVSFTDQNLHRKIAQSEVANLCTMSCFQLSRFFKRVTGVTFQGYLLHRRINEAMRLLANPKVSITDVCFTVGFGDLSYFTRTFQRYVGMPPSRFRLEATELASTRQSAQISSVPTALPSVLDPVEGPYP
>NZ_CP033116.1|WP_096348114.1|2954351_2955053_-|NrdJb
MALKISSKIVDYSVVKADEPAQTAEPTEAAIQLEEMHEKLKRPEFLEGSTYKIKTPTSEHAIYVTINDVILNHGSDHEIRRPFEIFINSKNMEHYQWISALTLIISAVFRKGGDCTFLVEELRSVFDPKGGYMKRGGRWMPSLVAEIGDVLEQHLKRIGMMVDEMDEHQRAYLEQKRAEFVAIKPQGQAAADCDDSTAAYPPGAQMCGKCHTQAAVQMDGCMTCLNCGDSKCG
>NZ_CP033116.1|WP_096348113.1|2955135_2957289_-|adenosylcobalamin-dependent-ribonucleoside-diphosphate-reductase
MNQTAKVQRLHNVVNDIPMQPASLDIWDTKYRLKTKDGVALDKTVDESYQRVARAIADVEAPELREHWYEQFLWALRHGAIPAGRITSNAGALEHKPATSTINCTVSATIGDSMDDILSKLHEAGLTLKAGCGIGYEFSTLRPKGAYVSGAGAYTSGPLSFMDIYDKMCFTVSSAGGRRGAQMATFDVGHPDVMDFIRAKREGGRLRQFNLSLLITEDFMAAVAADSDWKLSFPLTQAEVDADQLDLDNDDQVIWRELPATQRYLTRKDGRVACRVSKVIKARRIWDMIMTSTYDFAEPGFILIDRVNQMNNNWFCEEIRATNPCGEQPLPPHGACLLGSINLTLFVRDPFTDKARFDWDEYRKVVDIFTRMLDNVVEINGLPLEQQRNEIFRKRRHGMGFLGLGSTMTMLCMKYGEAKSLDFTEQVSKEMAVQGWRTALQLAEEKGAAPIMDEDFTVTEAMLVKRPEMRKDGIKAGQKIKGKVLWAKYSRYMQQVAGEDAELVNALIEKGGRFTHHSSIAPTGTISLSLANNASNGIEPSFAHHYFRNVIREGKKSKEKVDVFSFELLAYRHFVNPEALPSMEAASRNLPDYFIAADDVKPTEHVDVQAAAQKWIDSSISKTANVPTDYPYEDFKDIYRYAFEKGLKGCTTFRFNPEAFQGVLVKEQDLANTTYRFKLEDGSFVEAKGGDEIEYDGEMHSAANLYDALKEGYYGKF
>NZ_CP033116.1|WP_096348112.1|2957537_2958122_-|DUF1285-domain-containing-protein
MSKRQLPPQSLIDSIPGGAAGEAREPAPVHLWNPPLSGEMDMQIARDGTWYHEGDAIGRKALVQLFAGILKYDDDGRYYLVTPVERWAIKVDDAPFVATQLKVEGQGEQQELVFTTNLQDSFVAGKDHPIRVTVDPETQEPSPYVLVRTNLEALINRNLFYELAELAVEREHNGKTCLGVWSQECFFPIDGSPA
>NZ_CP033116.1|WP_096348111.1|2958132_2958729_-|DUF4823-domain-containing-protein
MRWIGLLVVLGLLAGCMKPSDMQKSARYYLGDAGLMNHYEIKRNATWRLQPDSSLYIAQGHFVPVGHPYARPNVVAEEAFAAAVQVFPLTRRAEQPLGLEESLEQAYLHRSDYLLYTRFARADDAVGDAEHWNESRDLGDVGLDRAVLQMMLMETSTRQLVDFAVVETRGGFMQFYQAEPEDLLRPPLEDYTRRLLGR
>NZ_CP033116.1|WP_096348110.1|2958751_2959642_-|B12-binding-domain-containing-radical-SAM-protein
MSAFPIDYIEPVFRPPSEAHSLILPVTNGCSWNNCTFCEMYTAPQKKFRARDEDQVLEEIRKSGEQLIVQRVFLADGDAMILPTKRLLRILEAIREHMPSVERVTSYCLPRNLKRKSVEELRQLREAGLAMLYVGAESGDDQVLERVNKGETYASTEEALSKSGEAGMQRSVMILNGLGGKGLSEQHALNSARLMTATQPEFLSTLVVSFPQGLARYRERFPDFEPLDQPSLFRELESLISMLELDNTVFRSDHASNALVLKGVLGADKERMLAQVRAAISRPEQARLRPEWMRGL
>NZ_CP033116.1|WP_096348109.1|2959641_2960607_-|amidohydrolase
MNAQARDYAFSDAHFHYVDFFQESEGIKALLEKMDESNIDHIMFSGIPVAKKWHENEPQRPRYYAGDDAAAYWYSATDFIILRALEHLTPDQRKRFHPFLSGFNPNDKNADAHIRRLLEMNPGVWKGLGEVFTRHDDLTALISGDVPRANNEAMYRIYALAEEFDLPVMVHSNITSKRERMPLYLEEIEDPLRYFPNVRFIWAHAGTSMELHRHQEKLEFLFDTVKRMLETYPNLYIDLSWTVLDPYLVNKDGEANAQWVKLVTDYPDRFMLGSDVVGSFKNMDKYLDAFIPFLDALPEEVAHKVARDNFLAVLPSEKEQD
>NZ_CP033116.1|WP_096348143.1|2960749_2961388_-|TetR/AcrR-family-transcriptional-regulator
MQKESRKLREFRRREQEILDTALRLFLEQGEDSVTVEMIADEVGIGKGTIYKHFKSKAEIYLRLMLDYERDLSTLLNSEGIERDREALSRDYFEFRMSDPERYRLFDRLEEKLVKSNQLPELVEELHKIRASNFNHLTGVIQERIDDEKLENVPAYFHYCAAWALVHGAMAMYHSPFWQEVIEDKEGYMQFLMDIGVRMGNKSKRRKDTETP
>NZ_CP033116.1|WP_096348108.1|2961473_2962325_-|ABC-transporter-permease-subunit
MIASLPLSRRFRWTYAAYVLIFFVYLAAPLLVVGVFAFNDSRFPALPWQGFTLDWFIAEGGGRTGLFHDRAILRSVGTSALVASCVTMLSVSLATMNAFLFERHVFPGKNLLFILMLLPLVIPGVILGISILIFASRIANYFDFNHDIMLDMLRPGLLLVVLGQFAFLTTIATLVISARLRTFDTQLEEAACNLGASPLTAVRTVTLPFLAPAIIGAALVCFLMSFENFNTTLMLVGSDAPLTITLFSRLREGATPVLNAVSLLLMLGSMLLALISIRVQKKA
>NZ_CP033116.1|WP_096348107.1|2962321_2963200_-|ABC-transporter-permease
MAAPKVAARRLVGMSTLLLMLPLLLWLFLLIFLPHLDMFAVALRERVGFGEYRFSWMHFELFFSESLYWRTFLRTAVMSMLTTLLTLIIALPIAWYIAKLVRGRVRSLLFMACLIPFWVSELVRTYGWMILLRESGVISGVLQWSGLADAPVEMLYNDVAIMVGLIYASMLFMLVPLVTTLDSLDNSLVEAAYDLGGNHFTVTRDIIIPHAMPGIVSGSIVVFMLSLGNYLTPVLLGGKDSLWFTEQIFTQFITRFNWEQGAAFGVLLLVLSSLIVWLGLKLSGQSFAETMK

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Crispr_ID: NZ_CP033116_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP033116_2

4306584-4306683

Orphan

Consensus_repeat	Method
GCCATATTGGAGTGATCCATGCCCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP033116_2

>merge|NZ_CP033116|2|4306584-4306683|CRISPRCasFinder
CCCATGTTGGAATGGTCCATGCCGGCCATATTGGAGTGATCCATGCCCTGCATGCCGTCCATGCCGTCCATGCCAGCCATATTGGAGTGGTCCATGCCCT

>NZ_CP033116|2|2|4306584-4306683|CRISPRCasFinder
CCCATGTTGGAATGGTCCATGCCGG	CCATATTGGAGTGATCCATGCCCTGCATGCCGTCCATGCCGTCCATGCCA
GCCATATTGGAGTGGTCCATGCCCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP033116.1\|WP_096348546.1\|4316453_4319630_-\|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223911
NZ_CP033116.1\|WP_096347531.1\|4321225_4321588_+\|transposase	unknown	unknown	gnl\|CDD\|366690
NZ_CP033116.1\|WP_096348543.1\|4311359_4311854_-\|Cu(I)-responsive-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133383
NZ_CP033116.1\|WP_096348536.1\|4303568_4303793_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377540
NZ_CP033116.1\|WP_153274305.1\|4296258_4297677_-\|RND-transporter	unknown	unknown	gnl\|CDD\|224455
NZ_CP033116.1\|WP_153274306.1\|4297687_4298014_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP033116.1\|WP_096348538.1\|4305275_4306025_-\|copper-resistance-protein-B	unknown	unknown	gnl\|CDD\|377498
NZ_CP033116.1\|WP_096348540.1\|4307841_4308408_-\|copper-binding-protein	unknown	unknown	gnl\|CDD\|259873
NZ_CP033116.1\|WP_153274304.1\|4294865_4296257_-\|multicopper-oxidase-domain-containing-protein	unknown	unknown	gnl\|CDD\|259929
NZ_CP033116.1\|WP_096348542.1\|4309260_4310601_+\|GHKL-domain-containing-protein	unknown	unknown	gnl\|CDD\|340430
NZ_CP033116.1\|WP_096348548.1\|4310961_4311156_-\|heavy-metal-associated-domain-containing-protein	unknown	unknown	gnl\|CDD\|225328
NZ_CP033116.1\|WP_149332610.1\|4294352_4294844_-\|cupredoxin-family-protein	unknown	unknown	gnl\|CDD\|259873
NZ_CP033116.1\|WP_096348545.1\|4314990_4316457_-\|TolC-family-protein	unknown	unknown	gnl\|CDD\|224455
NZ_CP033116.1\|WP_096348541.1\|4308608_4309274_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_CP033116.1\|WP_153274307.1\|4298082_4298451_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP033116.1\|WP_096348537.1\|4303823_4305176_-\|APC-family-permease	unknown	unknown	gnl\|CDD\|223605
NZ_CP033116.1\|WP_096348547.1\|4319626_4320793_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273776
NZ_CP033116.1\|WP_096348535.1\|4301239_4303576_-\|cadmium-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319783
NZ_CP033116.1\|WP_153274308.1\|4298780_4300211_-\|IS1182-family-transposase	unknown	unknown	gnl\|CDD\|226192
NZ_CP033116.1\|WP_096348544.1\|4312324_4314898_-\|copper-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319783

Protein	Function_ID	Function_description	E-value
NZ_CP033116.1\|WP_096348546.1\|4316453_4319630_-\|efflux-RND-transporter-permease-subunit	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NZ_CP033116.1\|WP_096348543.1\|4311359_4311854_-\|Cu(I)-responsive-transcriptional-regulator	gnl\|CDD\|133383	cd01108, HTH_CueR, Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators. Helix-turn-helix (HTH) transcription regulators CueR and ActP, copper efflux regulators. In Bacillus subtilis, copper induced CueR regulates the copZA operon, preventing copper toxicity. In Rhizobium leguminosarum, ActP controls copper homeostasis; it detects cytoplasmic copper stress and activates transcription in response to increasing copper concentrations. These proteins are comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their conserved N-terminal domains contain winged HTH motifs that mediate DNA binding, while the C-terminal domains have two conserved cysteines that define a monovalent copper ion binding site. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements.	7.92018e-77
NZ_CP033116.1\|WP_096348536.1\|4303568_4303793_-\|hypothetical-protein	gnl\|CDD\|377540	pfam05656, DUF805, Protein of unknown function (DUF805). This family consists of several bacterial proteins of unknown function.	0.000972175
NZ_CP033116.1\|WP_153274305.1\|4296258_4297677_-\|RND-transporter	gnl\|CDD\|224455	COG1538, TolC, Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion].	6.94773e-22
NZ_CP033116.1\|WP_096348545.1\|4314990_4316457_-\|TolC-family-protein	gnl\|CDD\|224455	COG1538, TolC, Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion].	2.13084e-81
NZ_CP033116.1\|WP_096348538.1\|4305275_4306025_-\|copper-resistance-protein-B	gnl\|CDD\|377498	pfam05275, CopB, Copper resistance protein B precursor (CopB). This family consists of several bacterial copper resistance proteins. Copper is essential and serves as cofactor for more than 30 enzymes yet a surplus of copper is toxic and leads to radical formation and oxidation of biomolecules. Therefore, copper homeostasis is a key requisite for every organism. CopB serves to extrude copper when it approaches toxic levels.	1.26795e-79
NZ_CP033116.1\|WP_096348540.1\|4307841_4308408_-\|copper-binding-protein	gnl\|CDD\|259873	cd04211, Cupredoxin_like_2, Uncharacterized Cupredoxin-like subfamily. Cupredoxins contain type I copper centers and are involved in inter-molecular electron transfer reactions. Cupredoxins are blue copper proteins because they have an intense blue color due to the presence of a mononuclear type 1 (T1) copper site. Structurally, the cupredoxin-like fold consists of a beta-sandwich with 7 strands in 2 beta-sheets, which is arranged in a Greek-key beta-barrel. Some of these proteins have lost the ability to bind copper. Majority of family members contain multiple cupredoxin domain repeats; ceruloplasmin and coagulation factors V/VIII have six repeats; Laccase, ascorbate oxidase, and spore coat protein A, and multicopper oxidase CueO contain three repeats; and nitrite reductase has two repeats. Others are mono-domain cupredoxins, such as plastocyanin, pseudoazurin, plantacyanin, azurin, rusticyanin, stellacyanin, quinol oxidase and the periplasmic domain of cytochrome c oxidase subunit II.	4.37316e-39
NZ_CP033116.1\|WP_153274304.1\|4294865_4296257_-\|multicopper-oxidase-domain-containing-protein	gnl\|CDD\|259929	cd13860, CuRO_1_2dMco_1, The first cupredoxin domain of bacteria two domain multicopper oxidase. This subfamily includes bacterial two domain multicopper oxidases (2dMCOs) with similarity to McoN from Nitrosomonas europaea. 2dMCO is a trimeric type C blue copper oxidase. Each subunit houses a type 1 copper site in domain 1 and a type 2/type 3 trinuclear copper cluster at the subunit-subunit interface. The 2dMCO is proposed to be a key intermediate in the evolution of three domain MCOs. Multicopper oxidases couple oxidation of substrates with reduction of dioxygen to water. These MCOs are capable of oxidizing a vast range of substrates, varying from aromatic to inorganic compounds such as metals.	5.30497e-69
NZ_CP033116.1\|WP_096348542.1\|4309260_4310601_+\|GHKL-domain-containing-protein	gnl\|CDD\|340430	cd16954, HATPase_PhoQ-like, Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.	1.26935e-52
NZ_CP033116.1\|WP_096348548.1\|4310961_4311156_-\|heavy-metal-associated-domain-containing-protein	gnl\|CDD\|225328	COG2608, CopZ, Copper chaperone [Inorganic ion transport and metabolism].	2.78909e-16
NZ_CP033116.1\|WP_149332610.1\|4294352_4294844_-\|cupredoxin-family-protein	gnl\|CDD\|259873	cd04211, Cupredoxin_like_2, Uncharacterized Cupredoxin-like subfamily. Cupredoxins contain type I copper centers and are involved in inter-molecular electron transfer reactions. Cupredoxins are blue copper proteins because they have an intense blue color due to the presence of a mononuclear type 1 (T1) copper site. Structurally, the cupredoxin-like fold consists of a beta-sandwich with 7 strands in 2 beta-sheets, which is arranged in a Greek-key beta-barrel. Some of these proteins have lost the ability to bind copper. Majority of family members contain multiple cupredoxin domain repeats; ceruloplasmin and coagulation factors V/VIII have six repeats; Laccase, ascorbate oxidase, and spore coat protein A, and multicopper oxidase CueO contain three repeats; and nitrite reductase has two repeats. Others are mono-domain cupredoxins, such as plastocyanin, pseudoazurin, plantacyanin, azurin, rusticyanin, stellacyanin, quinol oxidase and the periplasmic domain of cytochrome c oxidase subunit II.	2.52381e-52
NZ_CP033116.1\|WP_096347531.1\|4321225_4321588_+\|transposase	gnl\|CDD\|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	1.67959e-07
NZ_CP033116.1\|WP_096348541.1\|4308608_4309274_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	5.34491e-72
NZ_CP033116.1\|WP_096348537.1\|4303823_4305176_-\|APC-family-permease	gnl\|CDD\|223605	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism].	4.59237e-28
NZ_CP033116.1\|WP_096348547.1\|4319626_4320793_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	1.28153e-79
NZ_CP033116.1\|WP_096348535.1\|4301239_4303576_-\|cadmium-translocating-P-type-ATPase	gnl\|CDD\|319783	cd02094, P-type_ATPase_Cu-like, P-type heavy metal-transporting ATPase, similar to human copper-transporting ATPases, ATP7A and ATP7B. The mammalian copper-transporting P-type ATPases, ATP7A and ATP7B are key molecules required for the regulation and maintenance of copper homeostasis. Menkes and Wilson diseases are caused by mutation in ATP7A and ATP7B respectively. This subfamily includes other copper-transporting ATPases such as: Bacillus subtilis CopA , Archeaoglobus fulgidus CopA, and Saccharomyces cerevisiae Ccc2p. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_CP033116.1\|WP_153274308.1\|4298780_4300211_-\|IS1182-family-transposase	gnl\|CDD\|226192	COG3666, COG3666, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	4.07744e-33
NZ_CP033116.1\|WP_096348544.1\|4312324_4314898_-\|copper-translocating-P-type-ATPase	gnl\|CDD\|319783	cd02094, P-type_ATPase_Cu-like, P-type heavy metal-transporting ATPase, similar to human copper-transporting ATPases, ATP7A and ATP7B. The mammalian copper-transporting P-type ATPases, ATP7A and ATP7B are key molecules required for the regulation and maintenance of copper homeostasis. Menkes and Wilson diseases are caused by mutation in ATP7A and ATP7B respectively. This subfamily includes other copper-transporting ATPases such as: Bacillus subtilis CopA , Archeaoglobus fulgidus CopA, and Saccharomyces cerevisiae Ccc2p. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0

>NZ_CP033116.1|WP_096348538.1|4305275_4306025_-|copper-resistance-protein-B
MSFFKSLAVTTLTGLVMMPALGLAQERRQDTTPRKDPLKVWGAQFEEFEYRYSDDDEELGVWSGDFFYGTDDLKVRWLTKGEYAIEEQAYEKLENQLVGQIPVSDFFDAKAGIRFDTPEGPDRTYAVLGIAGLAPQWFEIDANFYVSKDGDTSAELDAEYELLLTNYWILAAAFDATVAFSEDREIGVGKGLVSTETGLRLRYDLIDRSFSPYIGVVHERKYGDTADFARADGAGTEQWFAVIGARLSF
>NZ_CP033116.1|WP_096348537.1|4303823_4305176_-|APC-family-permease
MSKEQDRTTHYNEGSLTLAGTVMLGTGVMIGAGIFALTGQMAEMTGALFPLAFLAAAVIVSFSSYSYIKISNAYPSAGGIGMYLHKAYGDRLPTAFHALLMYFSMVIAQSFLARTFGSYTMQLFGGDESGLMVPILGVSLILAAFVINLLGNQMVQGVASFIGVLKITGILIIGLVGVWLADSLAVDFSSTGETGVAGNFLGATALGILAFKGFTTITNSGSEVKDPRRNVGRAIIISIVACVVIYTLVGFAVASNLSLAEIIETRDYSLAAAARPVLGEYGVWFTVAIAMMATAGGILASIFAVSRMLAMLTEMKLVPHSHFGMSGSIQKHTLVYTVVLGLILTAFFDLSRIAALGIIFYLIMDIAIHWGVLRYLREDVKAVSWVPVVAIMLDLLALGGFVWVKLNSDPFVLGVAVVAMIVIAIGEQVFLTSSARKKAVDDEHAHADHH
>NZ_CP033116.1|WP_096348536.1|4303568_4303793_-|hypothetical-protein
MMNESMYGNAMWSGHWLWTLVVAIVVVPVWQICRRTGYPGWLGLLMLIPMVNLVLLYFIAFADWPAHKAGTGNE
>NZ_CP033116.1|WP_096348535.1|4301239_4303576_-|cadmium-translocating-P-type-ATPase
MSDHQHDHHDHESRGENAVKDPVCGMSVDPHTAEHRSQHAGKSWYFCSSRCQSKFEDDSEKYLGEKSAEAEPVAPGTMYTCPMHPEIRQQGPGDCPICGMGLEPEEVSLNDGPSAELTDMTRRFWIGLVLTLPVFLLEMGGHLTGLDHIVSPQISNWIQLLLATPVVVYCGWPFFVRGWKSVLSRNLNMFTLISIGTGVALFYSLVATLMPQIFPGAFRQEDGSVAVYFEAAAVIVVLVLLGQVLELRAREKTSGAIKALLDLAPATARKLSDDGDESDVTLEQIKVGDRLRVRPGDKVPLDGEVLEGSSNVDESMVTGEPLAVSKKAGAQVVGGSINQQGSFIMRADKVGRDTMLSQIVQMVANAQRSRAPIQGLADKVAGWFVPAVIVIAVIAFVVWSIYGPTPPMAFGLIAAVSVLIIACPCALGLATPMSIMVGVGRGAQIGVLIRDAEALERMEKVDTVVVDKTGTLTEGKPQVTKLVTADGFSDEDLMRYAAGLEKGSEHPLAHAIIEKAKAMQLTLSDAYNFDSPNGKGVTGKIDGKRVLLGNRLLMESEAVDTSAFDKEADELRKDGATVIFAAVDGKICGLLAIADPVKETTAAAIAALQNEGVRVVMLTGDNRTSAEAVARKLRIDEVEAEVLPEDKGKIVQRLKDEGRIVAMAGDGVNDAPALATADVGIAMGTGTDVAIESSGITLLRGDLMGIVEARKLSRATMRNIRQNLFFAFVYNAAGIPVAAGLLYPFTGILLSPIIAAAAMSLSSVSVITNALRLRVIKL
>NZ_CP033116.1|WP_153274308.1|4298780_4300211_-|IS1182-family-transposase
MKRFIQGEHRGQSTLLPESLDDYVSDINPVRVVDVFVDELDLAKLGFDGVIPAETGRPAYHPAILLKIYIYGYLNRIQSSRRLEREAQRNVELMWLTGRLMPDFKTIANFRKDNSKAIRGVCRQFVLLCQQLGLFSENLVAIDGSKFKAVNNRDRNFTSAKLKRRMEEIEASISRYLASLDAADRQIPSDSKPDTVSLEDKIAKLKAQMKELQGIESQLNESPDKQVSLTDPDARSMMTRGSGIVGYNVQTAVDTQHHLIVAHEVTNRGSDRDQLSSMAKQAREAIGVETLSVVADRGYFKGEEILACYDANVTAYVPKPMTSSAKADGRFNKDAFVYDATRNEYTCPAGEALIWRFSSVEKGMNMHCYWSSKCQSCTLKSQCTPSTNRRVKRWEHEAVLEEMQRRLTRAPEMMKVRKRTVEHPFGTLKQWMGATHFLTRKLNGVSAEMSLNVLAYNMKRVMKIIGTEGLLKAMAA
>NZ_CP033116.1|WP_153274307.1|4298082_4298451_-|hypothetical-protein
MKTGVLRTCLLWLMILIIPAQAVAGAFSTSCAATPPATQQNEMPVEHAHHAMAEQTHDDTGQVVHSGCVLCAVSCHGISALTSCNSEPLAVFAPVLSGVPAYLLFVGQTPEPLKRPPRTVLL
>NZ_CP033116.1|WP_153274306.1|4297687_4298014_-|hypothetical-protein
MFSPTYCIGGLLAVLAWHSHAQATQPDPSGANVVPPVTYQSPLHSYRGFEHQAPGDWREANATVGRIGGWQAYAAEVWEASQSQDDGADAGIDNAADAGGDANSHQHH
>NZ_CP033116.1|WP_153274305.1|4296258_4297677_-|RND-transporter
MNKTNTAPARLGFIGVLLLTVAGCAGLAPQSSLEQVQQQSAELTGQDALHWATEQDQPPVVRERIAELLAEPLALESAVEIALMNNPGLQARLFDLGIADAQRVQASRLPNPGFSIGRMTRGSEVEWERGLHLNLGSLIALPLTRRIAEGQNAQVQREVSLSVMRLATDTRIAWYRAVAAQQSLAYSEQVLQAADAGAEMAHRMAAVGNYSALQQAREQSFYAEAALSHLQARQEQVASHERLVRLLGLWGEQTNFTLPERLPDVPAEPLDQPDIEQQAMASRLDVQAAQQGAERLATNLKLGKATRFINVLELGISNNSSNEEPVQRGYEITVELPLFDWSGARMAGNEARYMQQLQRTAEVAINARSQVRESYQAYRTAWDVAAHYRDEIVPLRKRISEENMLLYNGMFIGVFELLADAREQISTVNRYLQAQSDFWVAQSELDLVRFGPVTPSEANSASTTPASPAGGH
>NZ_CP033116.1|WP_153274304.1|4294865_4296257_-|multicopper-oxidase-domain-containing-protein
MVSRRDFFMGAGAITAAVAASSVSRVSLAGLPEPVIQSSPETMAPLEPNTGRPYKPVVTLNGWTLPWRMNNGVKEFHLVAEPVVREMAPGFNAHLWGYNGQSPGPTIEVVEGDRVRIFVTNKLPEHTSIHWHGQRLPNGMDGVAGLNQRAIPAGKTYVYEFEAKRPGTFMYHPHADEMVQMAMGMMGFWVTHPRDAHPNIDEVDRDYCFLLNAYDVEPGSYTPKIMEMLDFNIWTFNSRVFPGIDPLVARKDDKVRIRVGNLTMTNHPIHLHGHEFEVTGTDGGPVPRGARWPEVTTDVAVGQMRQIEFIASDLGDWAFHCHKSHHTMNAMGHDVPTMLGVDHRKVVTQINSLIPDYMVMGERGMADMAEMQMPLPENTIPMMTGDGPFGSVEMGGMFTMLKVRADQPAGDYSDPGWYQQPEGTQAFEWTGPLAEPARFKSESTTGKPAVEVQVRKPTGHSGH
>NZ_CP033116.1|WP_149332610.1|4294352_4294844_-|cupredoxin-family-protein
MNTLIRITVIAALSTLSFGVLAHGDAEDSARSAMPPEQKAWGIGASEDQVDRELVIRMNDNMRFTPDHFEVAEGETLKLVIKNEGKMLHELVLGTAAELKEHAALMAKFPGMEHDEPYMAHVAAGQTQTLIWTFNRAGRFDFACLLPGHFQAGMVGGLEVSTN
>NZ_CP033116.1|WP_096348540.1|4307841_4308408_-|copper-binding-protein
MSLSRFAVAAMAMSVSVSVLALGAGAHDGGHGKAVNIGEAANASDASRTINVVMHDNYYEPEAIDVKPGETVRFVIENKGSLVHEFNIGTASMHEAHQAEMMMMVEHGVIQGGKLNKEMMGMDHSMMGMDMDMGKGHSMKHDDPNSVLLEPGENKEIIWKFAEKGAIEFACNVPGHYQAGMYGDVNFN
>NZ_CP033116.1|WP_096348541.1|4308608_4309274_+|response-regulator-transcription-factor
MRLLLVEDDCLLAEGLASQLEKAGFSVDRTQTAKEAILLGEQEDYRVGVLDLGLPDGNGLDVLRSWRSSNASFPVLILTARGDWQDKVNGLKAGADDYLTKPFRTEELVARLNAIVRRSEGRVHTSVKAGGFELDENRQSLKIKDGSEHSLTGTEFRLLRCLMSRPGQVFSKEQLMEQLYNLSESPSDNIIEAYIRRLRKLVGANTIATRRGQGYLFDDAV
>NZ_CP033116.1|WP_096348542.1|4309260_4310601_+|GHKL-domain-containing-protein
MMLFKKPTSVKGTLLALLLPSGIALMATAWLVHGILLERMSWNFVESRLQDEVAFLETQIRQSDGKIDTLRTGDYFQEVFHHSFAIQSPTQTIISPSTWETLLGPLLQSDQQGAIRVRKTSAAGAPSDVIAFRKAFVVNDQPLVVIVSEDMAALKASQAELHAWTAIVSIMLILLLVGVIWIGITLSMRPVISLQASLKKLQGGEVSRIHVKAPEELQPLVKQLNQLLDFLDRRLERSRDALANLSHSVKTPIAAVRQILEDTSRPLDDDLRREMGSRLGDIDKQLEAEMRRSRFAGPQVGKSAFPVKQARDLLWMFGRLYPEKSFELTTDMTEEHRWPVEEHDLSEILGNLLDNAGKWSSTFVDLSLREDNKQMLIVVADDGTGVAQDAVSALGKRGLRLDEQTPGHGLGLAIVCDIVERYSGQTHFSHSSLGGLKIAIVFHRKT
>NZ_CP033116.1|WP_096348548.1|4310961_4311156_-|heavy-metal-associated-domain-containing-protein
MFRLHIPNMTCGGCAKSVTRALLNVDPQARIETDPPAREVRVNSDLAESAFLAALSEAGYPAKP
>NZ_CP033116.1|WP_096348543.1|4311359_4311854_-|Cu(I)-responsive-transcriptional-regulator
MNIGQASKLSGVSAKMIRYYEQIGLIPQAVRSDAGYRHYSLPEVHSLRFIRRARDLGFSVEQISALLVLWRDRDRASADVKAMALSHAAGLKAKIAELQAMAQTLEHLADHCHGNHRPDCPILTDLAAPAAAAEQWSQAPNRAPRFGVGTPASSRHRAAKEALS
>NZ_CP033116.1|WP_096348544.1|4312324_4314898_-|copper-translocating-P-type-ATPase
MASVSRQHHANPAVSADARFSLPVEGMTCASCVGRVERALKAVPGVQTASVNLATERADITFTGLADPQAAVRAIESAGYTVREETTELAIEDMTCASCVGRVEKALAKIPGVLEATVNLATERARVRYFVGVVSTVDLEAAVQQAGYKSRRLSAETANAGDQDTERRESEARALRRSFLTAAILTLPVFILEMGSHLIPAMHHWVMGVLGQQINWYVQFALATLVMFGPGLRFFRKGVPALLRGAPDMNSLVAVGTAAAYGYSIVATFVPEVLPQGTANVYFEAAAVIVTLILLGRMLEARAKGRTSQAIKRLVGLQAKTARVQHNGETVEIALDQVTTGDIVLVRPGEKIPVDGEVVEGASYVDESMITGEPVPVSKGMGAGVVGGTINKTGAFSFRVTKVGANTVLAQIIRLVEQAQGSKLPIQALVDKVTMWFVPAVMAAATLTFLVWLIFGPSPALTFALVNAVAVLIIACPCAMGLATPTSIMVGTGRAAELGVLFRKGEALQALRDVSVIALDKTGTLTKGRPELTDLVPAEGFEYNEVLALVAAVETRSEHPIAESIVTAAKQLNLTLAPIDSFDATPGFGVSAKVAGRTVAVGADRFMTQLGLDVSSFLSTAQRLGEQGKSPLYAAIDGRLAGVIAVADPIKETTPEAIKALHALGLKVAMITGDNAATAAAIAKQLGIDEVAAEVLPDGKVAALKRFRINGAQVAFVGDGINDAPALAEADVGLAIGTGTDVAIEAADVVLMSGDLRGVTNAIALSQATIRNIKQNLFWAFAYNAVLIPVAAGALYPLNGTLLSPIFAAAAMALSSVFVLGNALRLKRFRAPMSVEARSETSEGVIASPTSGLVDGH
>NZ_CP033116.1|WP_096348545.1|4314990_4316457_-|TolC-family-protein
MRRPSAKLLFLVSGFLFLAGCAAGPNYSSPALPSLPSSQFPTSFGETPAGLAAGAVDVAWWRAFDDPALVTLIRRALAVNHDIGIAAARLDEAKALLSENRQGFLPGGGATLSYEDRRRSKVETPPDQSRGSENYRGTIDASWEIDLFGRVRRSVEAAQAQVGSREALMRSVQAAVASEVAATWFELRGIEAEIAVVAGITQSQRESLALVERLVSAGSASEFDRLLAEALLRNVEAAAPELQRRRAVAANALAILVGETPQTLRLPPNTPVREALEVRTIVVGDPLSLISRRADIVAAERSLAAATARIGVETAGLYPDVQVQGSIGFVAGSLSALSWAGGQSGFIAPVIRWSFLDTGRVRARIAASEARTKEALILYDRTVLRALQEADDAFKAYGAAGSTLALRMQESEANRETARLARLQFSAGEGIYLDVLEAERSDLASRRALTAARTSQWLAVVSIYKALGGGWEVCEQSNQDCRGADGLK
>NZ_CP033116.1|WP_096348546.1|4316453_4319630_-|efflux-RND-transporter-permease-subunit
MTFPRFCIDRPIVAIVLSVLMMIAGIAAFFQLPLSEYPAVTPPTVQVTASYPGANPKVIAETVAAPLEQAITGVEGMQYMSSQSATDGRMILTVTFVQGTDADMAQVQVQNRVSSALPRLPEEVRRQGVITQKTSPDILMVVHLLSPDKRYDPLYISNYAYLQVRDDLSRIPGVSDVLVWGAGEYSMRLWLDPDLIAARGLTAGEVIAAVREQNVQVAAGSVGQTPDSNAAFQVAVNTLGRLTDEVQFGDIIIHTGDGGQVTRLRDVARVEMGADAYALRSLLDGEPAVALQIIQSPGANALDVSEAVRATMQRLEGKFPEGLSSRIAYDPTVFVRASLESVATTLLEAILLVVIVVMLFLRNWRASLIPLMAVPVSLIGTFAVMHLMGFSLNTLSLFGLVLSIGIVVDDAIVVVENVERHIENGEEPMQAARLAMDEVTGPIIAMTSVLAAVFIPTAFLSGLQGQFYQQFALTIAISTILSAVNSLTLSPALAGLLLRPRQAAILHDPRSLRGRADRLFRTLGQPFQRAPDAYGSTVRKIVGVSGVALLIYGGLLALTFFGFKVVPPGFVPMQDKYYLVAIAQLPNASSLDRTDAVVKQMSNIALTEPGVESVVAFPGLSINGFVNVPNAAVMFIMLDPFKDRTTPDLTATAIAGRLQAQFASIPDGFLGVFPPPPVPGLGATGGFKMQVEDRSGAGLAALMQQTQVLMTKATESGEVAGLMTSLDINAPQLDVTIDRTQVKSQGVHLADVFEALQVYLGSLYINDFNRFGRTYKVTAQADADHRMQAESIGRLQVRNAAGNMVPLSSFVSVTPSAGPDRVMHYNGYPTADISGGPMAGVSSGQAVAVMERLAKEVLPEGMSFEWTDLTYQQKLAGDLALYIFPLCVLLAYLILAAQYNSWLLPLAVLLIVPMCLLSAITGVWLAGGDNNVFVQIGLLVLVGLAAKNAILIVEFARSLEVAGSSALDAVVEACRLRLRPIVMTSLAFIAGVVPLILASGAGAEMRHAMGVAVFAGMLGVTLFGLFLTPVFYVVMQGLSARIERRRSRSTLHVRESKS
>NZ_CP033116.1|WP_096348547.1|4319626_4320793_-|efflux-RND-transporter-periplasmic-adaptor-subunit
MNIKRVILITAAIGAALVIAGCEEAVPSADSSQPPGVPVAEVIVRPVTPFAEFTGSLAAIERVELRPRVAGYLQDVSVPEGRFVKKGTTLFRIDPRVFQAAVNAAAARLREAEAALKLALTDHARAEQLFTQKVVARDRLDTATAALEVSKAQVDAAKAALAAAQLDLSFSHVTAPISGRVGQALVTAGNYVTSGVTPLTTIVSIDPLHVNFDIDERTYLRSVAANREIGDSQRTASEKVMVALLTDETYSRPGRIDFVSNSTDRGTGTIRIRAVVDNPDGQLTPGLFAKIKLETGTQQAAVLVSDQSIRTDQGSRYVLVVGSDNKTEYRPVVLGAMVDGLRVIEHGLQPGERIVVKGMVGPGMQVTPQSTAIEGSPIAALQTSGAGQ
>NZ_CP033116.1|WP_096347531.1|4321225_4321588_+|transposase
MNTSSVVKPAPKRRRFTSDFKASIVAACLEPGVSVSRIALDNRLNANMVRRWIRESQRSDTRYSTPSFVPVKLPAPALSSETRPHSAIRIEIPHTGGAVVVEWPTEQAHQCAALLRDLLR

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

68380 : 140473

Leptospira_phage(17.65%)

transposase,holin,integrase

attL 85403:85462|attR 145622:146851

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096348146.1\|68380_69468_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	9.9e-44	38.0
WP_096346984.1\|70793_72392_-\|holin	choline dehydrogenase	A0A1V0S9M4	Catovirus	4.4e-56	30.0
WP_096346983.1\|72419_73874_-	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_096346982.1\|73925_74444_-	rubredoxin	NA	NA	NA	NA
WP_096346985.1\|74582_75800_-	alkane 1-monooxygenase	A0A1V0SBK9	Catovirus	3.6e-42	33.4
WP_153274254.1\|77562_79086_+\|transposase	IS21 family transposase	K4I413	Acidithiobacillus_phage	5.6e-154	53.7
WP_153274255.1\|79100_79856_+	AAA family ATPase	K4HZD4	Acidithiobacillus_phage	3.6e-77	59.6
WP_096346304.1\|81321_82497_+	pyridine nucleotide-disulfide oxidoreductase	NA	NA	NA	NA
WP_153274310.1\|82809_83166_+	IS66 family insertion sequence element accessory protein TnpB	S5VXZ8	Leptospira_phage	1.5e-17	37.8
WP_153274256.1\|85135_85363_-	IS66 family insertion sequence element accessory protein TnpB	S5WJH4	Leptospira_phage	3.3e-10	43.8
85403:85462	attL	NA	NA	NA	NA
WP_096345320.1\|85462_85747_+\|transposase	transposase	A9YX41	Burkholderia_phage	1.6e-06	32.3
WP_153274257.1\|85743_86598_+\|transposase	IS3 family transposase	U5P429	Shigella_phage	2.7e-81	57.7
WP_096347161.1\|86626_86830_+	hypothetical protein	NA	NA	NA	NA
WP_096347160.1\|87280_88696_-	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_153274258.1\|88692_91866_-	efflux RND transporter permease subunit	NA	NA	NA	NA
WP_096347846.1\|91871_93020_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_096347848.1\|93213_93849_+	TetR family transcriptional regulator	NA	NA	NA	NA
WP_143520370.1\|93893_94160_-	hypothetical protein	NA	NA	NA	NA
WP_149331781.1\|94241_94460_-	YgdI/YgdR family lipoprotein	NA	NA	NA	NA
WP_096346981.1\|95977_96970_+	lipid A deacylase LpxR family protein	NA	NA	NA	NA
WP_096344939.1\|99637_100534_-	alpha/beta hydrolase	A0A223FN69	NY_014_poxvirus	8.8e-06	32.8
WP_096344938.1\|100526_101015_-	PaaI family thioesterase	NA	NA	NA	NA
WP_096344937.1\|101011_101497_-	PaaI family thioesterase	NA	NA	NA	NA
WP_096344936.1\|101651_102260_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_096344935.1\|102418_103504_-	aldo/keto reductase	NA	NA	NA	NA
WP_096344934.1\|103596_104403_-	dienelactone hydrolase family protein	NA	NA	NA	NA
WP_096344933.1\|104526_105105_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_096344940.1\|105249_105918_-	cupin	NA	NA	NA	NA
WP_096344932.1\|105981_106602_-	glutathione S-transferase	NA	NA	NA	NA
WP_096344931.1\|106787_107177_-	hypothetical protein	NA	NA	NA	NA
WP_096344930.1\|109459_110431_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_096344929.1\|110739_110931_-	4-oxalocrotonate tautomerase family protein	NA	NA	NA	NA
WP_096344928.1\|110942_111746_-	2-oxo-3-hexenedioate decarboxylase	NA	NA	NA	NA
WP_096344927.1\|111742_112780_-	4-hydroxy-2-oxovalerate aldolase	E5EQ69	Micromonas_sp._RCC1109_virus	2.1e-43	31.4
WP_096345073.1\|112793_113732_-	acetaldehyde dehydrogenase (acetylating)	E5EQ71	Micromonas_sp._RCC1109_virus	2.7e-37	35.3
WP_153274259.1\|113785_114571_-	2-oxopent-4-enoate hydratase	NA	NA	NA	NA
WP_096344620.1\|114573_115440_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_096344621.1\|115447_116908_-	2-hydroxymuconic semialdehyde dehydrogenase	NA	NA	NA	NA
WP_096344622.1\|116939_117860_-	catechol 2,3-dioxygenase	NA	NA	NA	NA
WP_096344623.1\|117870_118191_-	2Fe-2S iron-sulfur cluster binding domain-containing protein	NA	NA	NA	NA
WP_096344624.1\|118333_119110_-	1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase	NA	NA	NA	NA
WP_096344625.1\|119248_120259_-	ring-hydroxylating dioxygenase ferredoxin reductase family protein	NA	NA	NA	NA
WP_096344626.1\|120268_120757_-	benzoate 1,2-dioxygenase small subunit	NA	NA	NA	NA
WP_096344627.1\|120757_122113_-	benzoate 1,2-dioxygenase large subunit	NA	NA	NA	NA
WP_096344629.1\|122458_123064_-	hypothetical protein	A9YX10	Burkholderia_phage	2.2e-45	49.0
WP_096344630.1\|123742_124471_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.6e-18	25.8
WP_096344631.1\|124470_125229_-	ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	3.3e-14	29.0
WP_096344632.1\|125225_126254_-	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_096344633.1\|126276_127137_-	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_096344634.1\|127188_128370_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_096344635.1\|128450_129716_-	OprD family porin	NA	NA	NA	NA
WP_096344636.1\|130524_132192_+	SidA/IucD/PvdA family monooxygenase	NA	NA	NA	NA
WP_096344637.1\|132299_133547_+	serine hydrolase	NA	NA	NA	NA
WP_096344638.1\|133608_134502_+	3-hydroxyacyl-CoA dehydrogenase	NA	NA	NA	NA
WP_096344639.1\|135563_138224_+	hypothetical protein	NA	NA	NA	NA
WP_096344640.1\|138664_138889_-	helix-turn-helix transcriptional regulator	S5MTW4	Brevibacillus_phage	1.0e-08	43.5
WP_096344649.1\|139038_139275_+	hypothetical protein	NA	NA	NA	NA
WP_096344641.1\|139267_140473_+\|integrase	site-specific integrase	A0A1W6JTA0	Pseudomonas_phage	4.5e-37	31.0
145622:146851	attR	NA	NA	NA	NA

DBSCAN-SWA_2

375376 : 384936

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096345468.1\|375376_376039_+	response regulator	Q56AR1	Bacillus_thuringiensis_phage	1.1e-05	29.9
WP_096345469.1\|376035_377403_+	HAMP domain-containing protein	W8CYF6	Bacillus_phage	1.8e-18	26.9
WP_096345470.1\|377488_378262_+	glucose 1-dehydrogenase	Q06VL0	Trichoplusia_ni_ascovirus	7.1e-12	28.6
WP_096345471.1\|378349_382807_+	PAS domain-containing protein	A0A1V0SGX0	Hokovirus	2.7e-23	24.5
WP_096345634.1\|382913_383300_+	response regulator	W8CYM9	Bacillus_phage	5.1e-11	32.8
WP_096345635.1\|383376_384936_+	diguanylate cyclase	A0A127AWB9	Bacillus_phage	1.1e-14	39.1

DBSCAN-SWA_3

663403 : 727943

Staphylococcus_phage(14.29%)

transposase,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096346664.1\|663403_663871_-\|tRNA	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	NA	NA	NA	NA
WP_096346610.1\|664178_665609_-	nitrogen regulation protein NR(I)	NA	NA	NA	NA
WP_096346611.1\|665613_666693_-	nitrogen regulation protein NR(II)	Q8QKV7	Ectocarpus_siliculosus_virus	2.1e-06	23.9
WP_096346612.1\|667032_667677_-	DUF4124 domain-containing protein	NA	NA	NA	NA
WP_096346613.1\|667802_669206_-	glutamate--ammonia ligase	NA	NA	NA	NA
WP_096346614.1\|669662_671474_+	translational GTPase TypA	NA	NA	NA	NA
WP_096346615.1\|671638_672958_+	glycerophosphodiester phosphodiesterase	NA	NA	NA	NA
WP_096346616.1\|672950_673487_+	DUF924 domain-containing protein	NA	NA	NA	NA
WP_096346617.1\|673547_673973_+	VOC family protein	NA	NA	NA	NA
WP_096346618.1\|673976_675596_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_096346619.1\|675898_677275_+	META domain-containing protein	NA	NA	NA	NA
WP_096346620.1\|677316_677898_+	NnrU family protein	NA	NA	NA	NA
WP_096346665.1\|677935_678322_-	hypothetical protein	NA	NA	NA	NA
WP_096346621.1\|678463_679435_+	prolyl aminopeptidase	NA	NA	NA	NA
WP_096346622.1\|679450_679888_+\|tRNA	D-tyrosyl-tRNA(Tyr) deacylase	NA	NA	NA	NA
WP_096346623.1\|679903_680491_-	2-hydroxychromene-2-carboxylate isomerase	NA	NA	NA	NA
WP_096346624.1\|680524_681253_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_096346625.1\|681375_681870_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_096346626.1\|681910_683590_-	carboxylesterase family protein	A0A0M4JT58	Mollivirus	5.1e-31	27.1
WP_096346627.1\|683780_684488_-	16S rRNA (uracil(1498)-N(3))-methyltransferase	NA	NA	NA	NA
WP_096346628.1\|684484_685270_-	twin-arginine translocase subunit TatC	A0A1B1IVR7	uncultured_Mediterranean_phage	3.4e-30	35.4
WP_096346629.1\|685259_685703_-	twin-arginine translocase subunit TatB	NA	NA	NA	NA
WP_096346630.1\|685708_685939_-	twin-arginine translocase TatA/TatE family subunit	NA	NA	NA	NA
WP_096346631.1\|685982_686315_-	phosphoribosyl-ATP diphosphatase	NA	NA	NA	NA
WP_096346632.1\|686307_686721_-	phosphoribosyl-AMP cyclohydrolase	NA	NA	NA	NA
WP_096346633.1\|686780_688391_-	ubiquinone biosynthesis regulatory protein kinase UbiB	M4QMK7	Micromonas_pusilla_virus	3.3e-35	30.1
WP_096346634.1\|688387_689011_-	SCP2 domain-containing protein	NA	NA	NA	NA
WP_096346666.1\|689010_689772_-	bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE	NA	NA	NA	NA
WP_096346635.1\|689942_690218_+	polyhydroxyalkanoic acid system protein	NA	NA	NA	NA
WP_096346636.1\|690324_690747_+	phasin family protein	NA	NA	NA	NA
WP_096346637.1\|690767_691598_+	phasin family protein	NA	NA	NA	NA
WP_096346638.1\|691751_692186_+	poly(3-hydroxyalkanoate) granule-associated protein PhaI	NA	NA	NA	NA
WP_096346639.1\|692230_692845_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_096346640.1\|692854_694486_-	class II poly(R)-hydroxyalkanoic acid synthase	NA	NA	NA	NA
WP_096346641.1\|694525_695383_-	poly(3-hydroxyalkanoate) depolymerase	A0A1L7N183	Ralstonia_phage	2.6e-71	50.4
WP_096346642.1\|695406_697086_-	class II poly(R)-hydroxyalkanoic acid synthase	NA	NA	NA	NA
WP_096346643.1\|697330_697720_-	DUF971 domain-containing protein	NA	NA	NA	NA
WP_096346644.1\|697814_699155_-\|protease	ATP-dependent protease ATPase subunit HslU	A0A2H5BJT2	Erwinia_phage	1.1e-47	30.7
WP_096346667.1\|699176_699707_-\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_096346645.1\|699902_700499_-	cell division protein	NA	NA	NA	NA
WP_096346646.1\|700504_702250_-\|tRNA	arginine--tRNA ligase	A0A2K9L6Z2	Tupanvirus	3.1e-87	34.9
WP_096346647.1\|702330_704544_-	primosomal protein N'	NA	NA	NA	NA
WP_022963663.1\|704768_704981_+	50S ribosomal protein L31	NA	NA	NA	NA
WP_096346668.1\|705007_705802_+	nuclease	V5UN65	Mycobacterium_phage	1.6e-06	34.1
WP_096346648.1\|705798_707241_+\|protease	M48 family metalloprotease	NA	NA	NA	NA
WP_096346649.1\|707337_708600_+	malate dehydrogenase	NA	NA	NA	NA
WP_096346650.1\|708646_709705_-\|protease	ATP-dependent Clp protease ATP-binding subunit	K4FB40	Cronobacter_phage	8.2e-27	31.0
WP_096346651.1\|709726_710773_-	aliphatic amidase	NA	NA	NA	NA
WP_096346669.1\|710803_712411_-	GAF domain-containing protein	NA	NA	NA	NA
WP_096346652.1\|712524_712848_-	zinc ribbon domain-containing protein	NA	NA	NA	NA
WP_096346653.1\|712917_714147_-	acetamidase/formamidase family protein	A0A1V0S8X7	Catovirus	1.9e-136	58.9
WP_096346654.1\|714587_715832_+	urea ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_096346655.1\|715906_716830_+	urea ABC transporter permease subunit UrtB	NA	NA	NA	NA
WP_096346656.1\|716857_717994_+	urea ABC transporter permease subunit UrtC	NA	NA	NA	NA
WP_096346657.1\|717990_718731_+	urea ABC transporter ATP-binding protein UrtD	A0A2H4PQG7	Staphylococcus_phage	9.8e-19	28.2
WP_096346658.1\|718746_719436_+	urea ABC transporter ATP-binding subunit UrtE	A0A2H4PQG7	Staphylococcus_phage	4.1e-11	24.1
WP_096347531.1\|725632_725995_+\|transposase	transposase	A0A0P0ZBP6	Stx2-converting_phage	8.7e-05	36.7
WP_096347532.1\|725991_726327_+	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_096347533.1\|726401_727943_+\|transposase	IS66 family transposase	A0A218MNE7	uncultured_virus	3.6e-124	51.4

DBSCAN-SWA_4

1820913 : 1860635

Shigella_phage(33.33%)

transposase,integrase

attL 1816309:1816324|attR 1840586:1840601

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1816309:1816324	attL	NA	NA	NA	NA
WP_096344619.1\|1820913_1822344_+\|transposase	IS1182 family transposase	NA	NA	NA	NA
WP_096345893.1\|1822988_1824138_+\|transposase	IS3 family transposase	U5P429	Shigella_phage	1.6e-100	65.7
WP_123891502.1\|1825365_1826121_+	AAA family ATPase	K4HZD4	Acidithiobacillus_phage	3.6e-77	59.6
WP_096344956.1\|1826601_1827474_-	EamA family transporter	NA	NA	NA	NA
WP_096344954.1\|1827520_1828282_-	2OG-Fe dioxygenase family protein	NA	NA	NA	NA
WP_096344953.1\|1828291_1829515_-	argininosuccinate synthase	NA	NA	NA	NA
WP_096344955.1\|1829638_1830574_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_143520261.1\|1831608_1832064_+	hypothetical protein	NA	NA	NA	NA
WP_096344950.1\|1832071_1832329_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_096344949.1\|1832418_1832778_+	hypothetical protein	NA	NA	NA	NA
WP_096344948.1\|1833289_1834165_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_096344947.1\|1834218_1834953_+	serine/threonine protein phosphatase	K4K650	Caulobacter_phage	1.9e-43	43.1
WP_096344946.1\|1834987_1836307_+	hypothetical protein	NA	NA	NA	NA
WP_096344945.1\|1836372_1836696_+	hypothetical protein	NA	NA	NA	NA
WP_143520260.1\|1838818_1840117_+	hypothetical protein	NA	NA	NA	NA
WP_096344942.1\|1840117_1840750_+	lysine transporter LysE	NA	NA	NA	NA
1840586:1840601	attR	NA	NA	NA	NA
WP_096344941.1\|1840728_1841541_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_096348146.1\|1842203_1843290_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	9.9e-44	38.0
WP_096346757.1\|1843616_1844237_-	membrane integrity-associated transporter subunit PqiC	NA	NA	NA	NA
WP_096346756.1\|1844239_1845919_-	MCE family protein	NA	NA	NA	NA
WP_096346509.1\|1846058_1847145_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	8.7e-48	38.7
WP_153274276.1\|1847179_1847728_-	paraquat-inducible membrane protein A	NA	NA	NA	NA
WP_096346535.1\|1847724_1848354_-	paraquat-inducible protein A	NA	NA	NA	NA
WP_096346536.1\|1848525_1849935_-	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_096346537.1\|1849927_1853101_-	multidrug efflux RND transporter permease subunit	NA	NA	NA	NA
WP_096346538.1\|1853097_1854327_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_096346539.1\|1854566_1855034_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_096346540.1\|1855080_1855848_-	MipA/OmpV family protein	NA	NA	NA	NA
WP_096346541.1\|1855908_1856880_-	lipid A deacylase LpxR family protein	NA	NA	NA	NA
WP_096346542.1\|1857428_1858964_+	phospholipase D family protein	NA	NA	NA	NA
WP_153274277.1\|1859472_1860635_-\|transposase	IS3 family transposase	Q716C2	Shigella_phage	2.7e-87	51.9

DBSCAN-SWA_5

2517737 : 2559549

Enterobacteria_phage(10.53%)

transposase,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096347531.1\|2517737_2518100_+\|transposase	transposase	A0A0P0ZBP6	Stx2-converting_phage	8.7e-05	36.7
WP_096347532.1\|2518096_2518432_+	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_096347533.1\|2518506_2520048_+\|transposase	IS66 family transposase	A0A218MNE7	uncultured_virus	3.6e-124	51.4
WP_096344609.1\|2520692_2522618_+\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	3.3e-127	37.5
WP_096344610.1\|2522632_2523166_+	translation initiation factor IF-3	NA	NA	NA	NA
WP_149331953.1\|2523243_2523429_+	50S ribosomal protein L35	NA	NA	NA	NA
WP_096344612.1\|2523451_2523808_+	50S ribosomal protein L20	NA	NA	NA	NA
WP_096344613.1\|2523912_2524917_+\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2H4UW22	Bodo_saltans_virus	7.5e-30	38.9
WP_096344614.1\|2524956_2527338_+\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_036992243.1\|2527342_2527645_+	integration host factor subunit alpha	A0A0H3UZA0	Geobacillus_virus	5.2e-11	37.8
WP_096344615.1\|2527625_2527985_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_096344616.1\|2528410_2529496_-	hypothetical protein	NA	NA	NA	NA
WP_153274289.1\|2529742_2531014_+	hypothetical protein	NA	NA	NA	NA
WP_096344618.1\|2531204_2531468_+	AlpA family phage regulatory protein	Q7M299	Enterobacteria_phage	1.6e-11	52.6
WP_153274290.1\|2531932_2532529_+	inovirus Gp2 family protein	NA	NA	NA	NA
WP_153274282.1\|2532419_2533570_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	1.2e-100	65.7
WP_096346781.1\|2533640_2533928_+	inovirus Gp2 family protein	NA	NA	NA	NA
WP_096346780.1\|2534100_2534601_-	DUF1036 domain-containing protein	NA	NA	NA	NA
WP_096346779.1\|2534597_2535419_-	hypothetical protein	NA	NA	NA	NA
WP_096346783.1\|2536073_2536535_-	DNA repair protein RadC	NA	NA	NA	NA
WP_096346778.1\|2536588_2537530_-	hydrolase or metal-binding protein	NA	NA	NA	NA
WP_096346777.1\|2537607_2538615_-	alkaline phosphatase	A0A139ZPJ9	Marinitoga_camini_virus	3.3e-49	47.2
WP_096346776.1\|2538722_2539691_-	DUF932 domain-containing protein	A0A0H4INH5	Stenotrophomonas_phage	2.3e-60	41.6
WP_096346775.1\|2539782_2540091_-	hypothetical protein	NA	NA	NA	NA
WP_143520324.1\|2540427_2541555_-	hypothetical protein	NA	NA	NA	NA
WP_096346773.1\|2541799_2542339_-	DUF1523 family protein	A0A0S2MUU1	Bacillus_phage	3.4e-05	30.1
WP_096346772.1\|2542618_2543623_+	carboxylate--amine ligase	NA	NA	NA	NA
WP_096346771.1\|2543674_2544811_+\|protease	trypsin-like serine protease	W5SAB9	Pithovirus	7.7e-07	26.8
WP_096346770.1\|2544884_2546018_+	phosphoribosyltransferase	A0A172Q0Y1	Acinetobacter_phage	2.5e-29	28.4
WP_096346769.1\|2546007_2546766_+	trehalose phosphatase	NA	NA	NA	NA
WP_096346768.1\|2546758_2547853_+\|protease	cysteine protease StiP family protein	A0A172Q0S8	Acinetobacter_phage	3.0e-40	34.8
WP_096346767.1\|2547853_2548795_+	HpcH/HpaI aldolase/citrate lyase family protein	NA	NA	NA	NA
WP_096346766.1\|2548969_2549578_+	stress protein	A0A1J0GW82	Streptomyces_phage	3.5e-14	30.3
WP_096346765.1\|2549577_2550783_+	tellurium resistance protein TerA	NA	NA	NA	NA
WP_096346764.1\|2550831_2551281_+	tellurite resistance TerB family protein	Q1MVI3	Enterobacteria_phage	8.0e-08	25.6
WP_096346782.1\|2551291_2552341_+	TerC/Alx family metal homeostasis membrane protein	A0A1D7XFL1	Escherichia_phage	2.5e-76	46.9
WP_096346763.1\|2552360_2552936_+	TerD family protein	K4JRX3	Caulobacter_phage	3.8e-34	41.3
WP_096346762.1\|2552963_2553542_+	TerD family protein	NA	NA	NA	NA
WP_096346761.1\|2553801_2554938_+	DUF1311 domain-containing protein	NA	NA	NA	NA
WP_096346760.1\|2555072_2556257_+	DUF4236 domain-containing protein	NA	NA	NA	NA
WP_096346759.1\|2556346_2556715_+	hypothetical protein	NA	NA	NA	NA
WP_153274255.1\|2557255_2558011_-	AAA family ATPase	K4HZD4	Acidithiobacillus_phage	3.6e-77	59.6
WP_153274254.1\|2558025_2559549_-\|transposase	IS21 family transposase	K4I413	Acidithiobacillus_phage	5.6e-154	53.7

DBSCAN-SWA_6

3221573 : 3281552

Leptospira_phage(14.29%)

transposase,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096344815.1\|3221573_3222266_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_143520252.1\|3222392_3222539_-	DUF4177 domain-containing protein	NA	NA	NA	NA
WP_096344817.1\|3223415_3226463_-	efflux RND transporter permease subunit	S5VTK5	Leptospira_phage	2.5e-44	21.3
WP_096344818.1\|3226459_3227626_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_096344819.1\|3227786_3228419_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_096344820.1\|3228426_3229683_-	D-serine ammonia-lyase	NA	NA	NA	NA
WP_096344821.1\|3229749_3229926_+	DUF2897 family protein	NA	NA	NA	NA
WP_096344822.1\|3229978_3230509_+	DUF2058 domain-containing protein	NA	NA	NA	NA
WP_096344858.1\|3230569_3231202_-\|protease	ATP-dependent zinc protease	NA	NA	NA	NA
WP_096344823.1\|3231500_3232148_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_096344824.1\|3232283_3234080_+	DUF1446 domain-containing protein	NA	NA	NA	NA
WP_096344825.1\|3234119_3234989_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_096344826.1\|3234990_3236607_+	acyl-CoA carboxylase subunit beta	NA	NA	NA	NA
WP_096344827.1\|3236621_3237809_+	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_096344828.1\|3237805_3238603_+	enoyl-CoA hydratase	NA	NA	NA	NA
WP_096344829.1\|3238624_3240592_+	acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha	NA	NA	NA	NA
WP_096344830.1\|3240801_3242451_+	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	1.5e-11	32.0
WP_096344831.1\|3242473_3243793_-	TRAP transporter large permease subunit	NA	NA	NA	NA
WP_096344859.1\|3243990_3244587_+	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_096344832.1\|3244857_3246102_+	OprD family porin	NA	NA	NA	NA
WP_096344833.1\|3246528_3247737_-	ammonium transporter	H8ZJB2	Ostreococcus_tauri_virus	4.2e-43	33.3
WP_096344834.1\|3248130_3249294_+	EAL domain-containing protein	NA	NA	NA	NA
WP_143520253.1\|3249310_3250627_-	sensor histidine kinase	NA	NA	NA	NA
WP_096344836.1\|3250623_3251295_-	response regulator transcription factor	W8CYM9	Bacillus_phage	7.0e-24	34.2
WP_096344837.1\|3251294_3251648_-	PepSY domain-containing protein	NA	NA	NA	NA
WP_096344838.1\|3251631_3251937_-	peptidase	NA	NA	NA	NA
WP_096344839.1\|3252044_3253124_+	hypothetical protein	NA	NA	NA	NA
WP_096344840.1\|3253184_3253901_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_096344841.1\|3253861_3254764_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_096344842.1\|3254757_3255768_-	hydroxyacid dehydrogenase	A0A1M7XU89	Cedratvirus	1.1e-17	27.3
WP_096344860.1\|3255777_3256584_-	phosphonate ABC transporter, permease protein PhnE	NA	NA	NA	NA
WP_096344843.1\|3256617_3257478_-	phosphate/phosphite/phosphonate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_096344844.1\|3257474_3258308_-	phosphonate ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	3.6e-09	26.6
WP_096344845.1\|3258494_3259073_-	NlpC/P60 family protein	A0A1S5SEZ8	Streptococcus_phage	2.8e-13	36.3
WP_096344846.1\|3259157_3259829_-	3-methyladenine DNA glycosylase	NA	NA	NA	NA
WP_096344847.1\|3259863_3260538_-\|tRNA	tRNA 2-thiocytidine(32) synthetase TtcA	A0A0U2S5Z2	Escherichia_phage	1.5e-79	67.0
WP_096344848.1\|3260739_3261606_-\|tRNA	tRNA 2-thiocytidine(32) synthetase TtcA	A0A0U2S5Z2	Escherichia_phage	2.0e-95	65.7
WP_096344849.1\|3261906_3262287_-	hypothetical protein	NA	NA	NA	NA
WP_143520254.1\|3262331_3264011_-	hypothetical protein	NA	NA	NA	NA
WP_153274255.1\|3264075_3264831_-	AAA family ATPase	K4HZD4	Acidithiobacillus_phage	3.6e-77	59.6
WP_153274254.1\|3264845_3266369_-\|transposase	IS21 family transposase	K4I413	Acidithiobacillus_phage	5.6e-154	53.7
WP_096345067.1\|3266552_3266888_-	hypothetical protein	NA	NA	NA	NA
WP_096345068.1\|3267155_3267641_-	hypothetical protein	NA	NA	NA	NA
WP_096345069.1\|3267739_3268447_+	hypothetical protein	A0A172Q076	Acinetobacter_phage	4.3e-16	28.6
WP_096345070.1\|3268634_3270086_-	hypothetical protein	NA	NA	NA	NA
WP_143520267.1\|3270082_3271951_-	hypothetical protein	NA	NA	NA	NA
WP_096348146.1\|3272097_3273184_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	9.9e-44	38.0
WP_096345086.1\|3273218_3276263_-	hypothetical protein	NA	NA	NA	NA
WP_153274297.1\|3276619_3280066_-	hypothetical protein	NA	NA	NA	NA
WP_153274270.1\|3280419_3281552_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	3.9e-51	45.4

DBSCAN-SWA_7

4254928 : 4325452

uncultured_virus(21.43%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096346996.1\|4254928_4255957_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	1.1e-105	56.4
WP_022961595.1\|4256197_4256413_+	30S ribosomal protein S21	NA	NA	NA	NA
WP_096346995.1\|4256710_4258579_+	DNA primase	A0A1S5REW9	Helicobacter_phage	2.6e-44	31.7
WP_096346994.1\|4258678_4260535_+	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.2e-36	37.2
WP_096345320.1\|4261651_4261936_+\|transposase	transposase	A9YX41	Burkholderia_phage	1.6e-06	32.3
WP_153274303.1\|4261932_4262787_+\|transposase	IS3 family transposase	U5P429	Shigella_phage	1.2e-81	58.1
WP_096347190.1\|4263004_4263682_-	hypothetical protein	NA	NA	NA	NA
WP_096347189.1\|4263696_4264431_-	HupE/UreJ family protein	NA	NA	NA	NA
WP_096347188.1\|4264477_4264834_-	hypothetical protein	NA	NA	NA	NA
WP_096347187.1\|4264949_4265237_+	metal-sensing transcriptional repressor	NA	NA	NA	NA
WP_096347186.1\|4265260_4266097_+	nickel/cobalt efflux transporter RcnA	NA	NA	NA	NA
WP_096347185.1\|4266089_4266545_+	DedA family protein	NA	NA	NA	NA
WP_096347184.1\|4266769_4268086_-	OprD family porin	NA	NA	NA	NA
WP_096347183.1\|4268365_4268581_+	hypothetical protein	NA	NA	NA	NA
WP_096347182.1\|4268906_4272041_-	CusA/CzcA family heavy metal efflux RND transporter	NA	NA	NA	NA
WP_096347181.1\|4272052_4272394_-	P-II family nitrogen regulator	NA	NA	NA	NA
WP_096347180.1\|4272410_4273976_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_096347191.1\|4274083_4275280_-	TolC family protein	NA	NA	NA	NA
WP_096347179.1\|4275776_4276451_+	heavy metal response regulator transcription factor	W8CYM9	Bacillus_phage	4.7e-36	38.6
WP_096347178.1\|4276447_4277854_+	heavy metal sensor histidine kinase	NA	NA	NA	NA
WP_096347177.1\|4278029_4278674_-	thioredoxin domain-containing protein	NA	NA	NA	NA
WP_096347176.1\|4278670_4279111_-	disulfide bond formation protein B	NA	NA	NA	NA
WP_096347175.1\|4279197_4279650_-	Cd(II)/Pb(II)-responsive transcriptional regulator	NA	NA	NA	NA
WP_096347174.1\|4279732_4281964_+	heavy metal translocating P-type ATPase	E4ZFI9	Streptococcus_phage	1.5e-142	46.3
WP_096347173.1\|4281994_4282090_+	DUF3703 domain-containing protein	NA	NA	NA	NA
WP_096347172.1\|4282086_4283040_+	bile acid:sodium symporter	NA	NA	NA	NA
WP_096347171.1\|4283670_4284924_+	TolC family protein	NA	NA	NA	NA
WP_096347170.1\|4284920_4286378_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_096347169.1\|4286374_4289530_+	efflux RND transporter permease subunit	NA	NA	NA	NA
WP_096347168.1\|4289526_4289883_+	copper-binding protein	NA	NA	NA	NA
WP_096347167.1\|4290018_4290303_+	hypothetical protein	NA	NA	NA	NA
WP_096347166.1\|4290428_4291796_+	heavy metal sensor histidine kinase	Q8QKV7	Ectocarpus_siliculosus_virus	4.8e-11	26.3
WP_096347165.1\|4291812_4292496_-	heavy metal response regulator transcription factor	W8CYM9	Bacillus_phage	1.6e-28	32.6
WP_096347164.1\|4292654_4292981_-	four-helix bundle copper-binding protein	NA	NA	NA	NA
WP_096347163.1\|4293306_4293921_+	undecaprenyl diphosphate synthase family protein	A0A076FI83	Aureococcus_anophage	1.4e-10	22.9
WP_096347162.1\|4294027_4294321_-	copper-binding protein	NA	NA	NA	NA
WP_149332610.1\|4294352_4294844_-	cupredoxin family protein	NA	NA	NA	NA
WP_153274304.1\|4294865_4296257_-	multicopper oxidase domain-containing protein	NA	NA	NA	NA
WP_153274305.1\|4296258_4297677_-	RND transporter	NA	NA	NA	NA
WP_153274306.1\|4297687_4298014_-	hypothetical protein	NA	NA	NA	NA
WP_153274307.1\|4298082_4298451_-	hypothetical protein	NA	NA	NA	NA
WP_153274308.1\|4298780_4300211_-\|transposase	IS1182 family transposase	NA	NA	NA	NA
WP_096348535.1\|4301239_4303576_-	cadmium-translocating P-type ATPase	A0A218MNH6	uncultured_virus	5.2e-90	37.2
WP_096348536.1\|4303568_4303793_-	hypothetical protein	NA	NA	NA	NA
WP_096348537.1\|4303823_4305176_-	APC family permease	NA	NA	NA	NA
WP_096348538.1\|4305275_4306025_-	copper resistance protein B	NA	NA	NA	NA
WP_096348539.1\|4306021_4307758_-	copper resistance system multicopper oxidase	NA	NA	NA	NA
WP_096348540.1\|4307841_4308408_-	copper-binding protein	NA	NA	NA	NA
WP_096348541.1\|4308608_4309274_+	response regulator transcription factor	NA	NA	NA	NA
WP_096348542.1\|4309260_4310601_+	GHKL domain-containing protein	NA	NA	NA	NA
WP_096348548.1\|4310961_4311156_-	heavy-metal-associated domain-containing protein	NA	NA	NA	NA
WP_096348543.1\|4311359_4311854_-	Cu(I)-responsive transcriptional regulator	NA	NA	NA	NA
WP_096348544.1\|4312324_4314898_-	copper-translocating P-type ATPase	A0A218MNH6	uncultured_virus	3.4e-95	34.5
WP_096348545.1\|4314990_4316457_-	TolC family protein	NA	NA	NA	NA
WP_096348546.1\|4316453_4319630_-	efflux RND transporter permease subunit	NA	NA	NA	NA
WP_096348547.1\|4319626_4320793_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_096347531.1\|4321225_4321588_+\|transposase	transposase	A0A0P0ZBP6	Stx2-converting_phage	8.7e-05	36.7
WP_096347532.1\|4321584_4321920_+	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_096347533.1\|4321994_4323536_+\|transposase	IS66 family transposase	A0A218MNE7	uncultured_virus	3.6e-124	51.4
WP_096344619.1\|4324021_4325452_+\|transposase	IS1182 family transposase	NA	NA	NA	NA

DBSCAN-SWA_8

4403717 : 4469533

Leptospira_phage(22.22%)

portal,transposase,integrase

attL 4396170:4396186|attR 4466892:4466908

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
4396170:4396186	attL	NA	NA	NA	NA
WP_096346879.1\|4403717_4403966_+\|portal	portal protein	NA	NA	NA	NA
WP_096346880.1\|4403958_4404303_+	monovalent cation/H(+) antiporter subunit G	NA	NA	NA	NA
WP_096346881.1\|4404289_4405201_+	DUF4040 domain-containing protein	NA	NA	NA	NA
WP_096346882.1\|4405197_4405482_+	NADH:quinone oxidoreductase	NA	NA	NA	NA
WP_096346883.1\|4405478_4406903_+	NADH-quinone oxidoreductase subunit J	NA	NA	NA	NA
WP_096346912.1\|4406905_4408417_+	proton-conducting membrane transporter	NA	NA	NA	NA
WP_096346884.1\|4408413_4410066_+	sodium:proton antiporter	NA	NA	NA	NA
WP_096346885.1\|4410385_4412038_+	sodium:solute symporter family protein	NA	NA	NA	NA
WP_096346913.1\|4412270_4413308_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_096346886.1\|4413464_4413725_-	DUF1145 domain-containing protein	NA	NA	NA	NA
WP_096346887.1\|4413752_4415501_-	sulfatase-like hydrolase/transferase	A0A1V0SA98	Catovirus	3.6e-27	26.2
WP_096346888.1\|4415959_4417024_+	glycosyltransferase	NA	NA	NA	NA
WP_096346889.1\|4416967_4417516_-	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	8.3e-23	37.5
WP_096346890.1\|4417549_4418857_-	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_096346891.1\|4418887_4419661_-	glucose-1-phosphate cytidylyltransferase	NA	NA	NA	NA
WP_096346892.1\|4419700_4420747_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_096346893.1\|4421012_4421909_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_096346894.1\|4422013_4422382_-	hypothetical protein	NA	NA	NA	NA
WP_096346895.1\|4422948_4423353_+	nucleoside diphosphate kinase regulator	NA	NA	NA	NA
WP_096346896.1\|4423384_4424704_-	amidohydrolase	NA	NA	NA	NA
WP_096346897.1\|4424719_4425787_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_096346898.1\|4426022_4426706_-	LrgB family protein	NA	NA	NA	NA
WP_096346899.1\|4426705_4427056_-	CidA/LrgA family protein	NA	NA	NA	NA
WP_096346900.1\|4427058_4427565_-	DUF934 domain-containing protein	NA	NA	NA	NA
WP_096346901.1\|4427561_4429229_-	nitrite/sulfite reductase	NA	NA	NA	NA
WP_096346902.1\|4429503_4430907_+	cytochrome c oxidase accessory protein CcoG	NA	NA	NA	NA
WP_096346903.1\|4430937_4432353_+	PLP-dependent aminotransferase family protein	NA	NA	NA	NA
WP_153274282.1\|4432924_4434074_+\|transposase	IS3 family transposase	U5P429	Shigella_phage	1.2e-100	65.7
WP_096348568.1\|4434359_4434908_-	hypothetical protein	NA	NA	NA	NA
WP_143520399.1\|4435009_4435786_-	hypothetical protein	NA	NA	NA	NA
WP_096348565.1\|4436851_4440058_-	type I restriction endonuclease subunit R	NA	NA	NA	NA
WP_096348564.1\|4440058_4441450_-	restriction endonuclease subunit S	NA	NA	NA	NA
WP_096348570.1\|4441446_4443432_-	SAM-dependent DNA methyltransferase	A0A220A2U5	Liberibacter_phage	3.7e-28	23.8
WP_096348562.1\|4444031_4444790_-	hypothetical protein	NA	NA	NA	NA
WP_096348561.1\|4444898_4445216_-	hypothetical protein	NA	NA	NA	NA
WP_096348559.1\|4446318_4446567_+	hypothetical protein	NA	NA	NA	NA
WP_096348558.1\|4446550_4447435_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_096348557.1\|4447939_4451248_-	AAA family ATPase	A7KV33	Bacillus_phage	1.7e-30	23.7
WP_096348556.1\|4451250_4452213_-	hypothetical protein	NA	NA	NA	NA
WP_096348555.1\|4452382_4453459_+	taurine catabolism dioxygenase TauD	NA	NA	NA	NA
WP_096348554.1\|4453870_4454320_-	hypothetical protein	NA	NA	NA	NA
WP_096348553.1\|4454834_4455716_+	hypothetical protein	NA	NA	NA	NA
WP_096348552.1\|4455997_4456978_-	pirin	NA	NA	NA	NA
WP_096348551.1\|4456977_4457238_-	hypothetical protein	NA	NA	NA	NA
WP_096348569.1\|4457367_4458438_-\|integrase	site-specific integrase	W6MYA3	Pseudomonas_phage	6.1e-46	36.2
WP_096344603.1\|4458796_4460227_+\|integrase	integrase family protein	Q5QF66	Pseudomonas_virus	8.2e-22	26.8
WP_096344604.1\|4460766_4461675_-	cation transporter	NA	NA	NA	NA
WP_022961489.1\|4461822_4462164_-	P-II family nitrogen regulator	NA	NA	NA	NA
WP_096344605.1\|4462178_4465280_-	efflux RND transporter permease subunit	S5VTK5	Leptospira_phage	2.4e-82	24.4
WP_096344606.1\|4465294_4466401_-	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_096344607.1\|4466397_4467822_-	TolC family protein	NA	NA	NA	NA
4466892:4466908	attR	NA	NA	NA	NA
WP_096346509.1\|4468446_4469533_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	8.7e-48	38.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP033116

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection