CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP042217	Enterococcus faecalis strain L8 plasmid pL8, complete sequence	1 crisprs	NA	0	1	5	0
NZ_CP042216	Enterococcus faecalis strain L8 chromosome, complete genome	2 crisprs	csa3,cas3,cas9,cas1,cas2,csn2,cas14j,DinG,DEDDh,RT	0	11	5	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP042217_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042217_1

84204-84307

Orphan

Consensus_repeat	Method
TTACACAAATGAAAATGTGTAAAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP042217_1

>merge|NZ_CP042217|1|84204-84307|CRISPRCasFinder
TTACACAAATGAAAATGTGTAAATGTGTAAAAAAACATTGATTATTTAAATTGTCTATTGTATAATTTAAGTATAGAGATTTACACAAATGTAAATGTGTAAAT

>NZ_CP042217|1|1|84204-84307|CRISPRCasFinder
TTACACAAATGAAAATGTGTAAAT	GTGTAAAAAAACATTGATTATTTAAATTGTCTATTGTATAATTTAAGTATAGAGAT
TTACACAAATGTAAATGTGTAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042217.1\|WP_002365953.1\|79111_80071_+\|conjugal-transfer-protein-TraA	unknown	unknown	unknown
NZ_CP042217.1\|WP_153246995.1\|86284_86395_-\|type-I-toxin-antitoxin-system-Fst-family-toxin	unknown	unknown	unknown
NZ_CP042217.1\|WP_002394799.1\|89264_89498_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042217.1\|WP_002369734.1\|74109_74295_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042217.1\|WP_002394802.1\|86889_87207_+\|heavy-metal-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|179188
NZ_CP042217.1\|WP_002403278.1\|77049_77355_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042217.1\|WP_002365954.1\|77936_78293_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042217.1\|WP_002354485.1\|89573_90260_+\|IS6-like-element-IS1216-family-transposase	unknown	unknown	gnl\|CDD\|225853
NZ_CP042217.1\|WP_002372553.1\|74366_77039_-\|surface-exclusion-protein-SEA1/PrgA	unknown	unknown	gnl\|CDD\|275124
NZ_CP042217.1\|WP_011109599.1\|78860_78929_-\|sex-pheromone-inhibitor-determinant	unknown	unknown	unknown
NZ_CP042217.1\|WP_010711268.1\|88365_88962_+\|recombinase-family-protein	unknown	unknown	gnl\|CDD\|239737
NZ_CP042217.1\|WP_002394798.1\|88978_89263_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042217.1\|WP_002382053.1\|85248_85590_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042217.1\|WP_153246994.1\|80071_81703_-\|peptide-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|173869
NZ_CP042217.1\|WP_002354485.1\|87483_88170_+\|IS6-like-element-IS1216-family-transposase	unknown	unknown	gnl\|CDD\|225853
NZ_CP042217.1\|WP_011109609.1\|73998_74091_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042217.1\|WP_010711041.1\|81729_82896_-\|TraB-family-protein	unknown	unknown	gnl\|CDD\|224828
NZ_CP042217.1\|WP_002382056.1\|82939_83947_-\|replication-initiator-protein-A	unknown	unknown	gnl\|CDD\|369151
NZ_CP042217.1\|WP_002403282.1\|85748_86045_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042217.1\|WP_153246996.1\|90341_90818_+\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806

Protein	Function_ID	Function_description	E-value
NZ_CP042217.1\|WP_010711268.1\|88365_88962_+\|recombinase-family-protein	gnl\|CDD\|239737	cd03768, SR_ResInv, Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1.	8.50077e-44
NZ_CP042217.1\|WP_153246994.1\|80071_81703_-\|peptide-ABC-transporter-substrate-binding-protein	gnl\|CDD\|173869	cd08504, PBP2_OppA, The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold. This family represents the periplasmic substrate-binding component of an ATP-binding cassette (ABC)-type oligopeptide transport system comprised of 5 subunits. The transport system OppABCDEF contains two homologous integral membrane proteins OppB and OppF that form the translocation pore; two homologous nucleotide-binding domains OppD and OppF that drive the transport process through binding and hydrolysis of ATP; and the substrate-binding protein or receptor OppA that determines the substrate specificity of the transport system. The dipeptide (DppA) and oligopeptide (OppA) binding proteins differ in several ways. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0
NZ_CP042217.1\|WP_002354485.1\|87483_88170_+\|IS6-like-element-IS1216-family-transposase	gnl\|CDD\|225853	COG3316, COG3316, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.80773e-92
NZ_CP042217.1\|WP_002394802.1\|86889_87207_+\|heavy-metal-binding-domain-containing-protein	gnl\|CDD\|179188	PRK00967, PRK00967, hypothetical protein; Provisional.	4.00631e-49
NZ_CP042217.1\|WP_010711041.1\|81729_82896_-\|TraB-family-protein	gnl\|CDD\|224828	COG1916, COG1916, Uncharacterized homolog of PrgY (pheromone shutdown protein) [Function unknown].	1.13596e-89
NZ_CP042217.1\|WP_002382056.1\|82939_83947_-\|replication-initiator-protein-A	gnl\|CDD\|369151	pfam06970, RepA_N, Replication initiator protein A (RepA) N-terminus. This of family of predicted proteins represents the N-terminus (approximately 80 residues) of replication initiator protein A (RepA), a DNA replication initiator in plasmids. Most proteins in this family are bacterial, but archaeal and eukaryotic members are also included.	1.67554e-28
NZ_CP042217.1\|WP_153246996.1\|90341_90818_+\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	1.45013e-16
NZ_CP042217.1\|WP_002372553.1\|74366_77039_-\|surface-exclusion-protein-SEA1/PrgA	gnl\|CDD\|275124	TIGR04320, hypothetical_protein, SEC10/PgrA surface exclusion domain. This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.	6.77357e-40
NZ_CP042217.1\|WP_002354485.1\|89573_90260_+\|IS6-like-element-IS1216-family-transposase	gnl\|CDD\|225853	COG3316, COG3316, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.80773e-92

>NZ_CP042217.1|WP_002382056.1|82939_83947_-|replication-initiator-protein-A
MENFQFYKSKEIYREKYYQMPKVFFTNEVYKSLSNDAKIAYMLLKDRFDNSVKNNWVDSEDNVYFIYTVAELMTLLNCREGKVSKIKKELEAVNLLKQKKGRVKKINGKIETTPNLLYLGKPNVTSEDVFKINEEQNNVNPVIAKIANTEKVNNINENPVIAKIANTEKVNDINENPVIAKIADNLFYTSYLDTLDTLDTKKEALQQQLLLDQFSEVQENTFLNKDSLKFIAAFSNTIQEAHEQVGTIIRAKTKVEKEYNLVLIGEDYQEEIDKCLRRVMHKIKTDSTVKSPKGLFYKSFYNLFVECALEKKSQLNKKSNSNTPGVITHNWVENQ
>NZ_CP042217.1|WP_010711041.1|81729_82896_-|TraB-family-protein
MSFESENKNVEKIIVSNKTYYLVGTSHISENSVKLVKEVIERVQPDTVSIELDKKRYEKYTNSNQWGNTDIIKIIKEKKLVVLISNIVYSAYQKKLANTKGTTQAGELIQAIKSAKEIGANIQLIDRDIQVTFKRMWRHLSFLEKPKLFMTFFTEFDDIEQDKLEEYLESDSFDKVFISLSKKYPSLYQDMITDRDKYMSTKLKNNSSQVNVVVVGKAHMKGIKEKLEKRTEFSLDNLNEIPPKKLSTKLLEFSLPAIIIILLVLSLVSGFEVGVSQILKWLVWNGGLAALFTCFALANPLTILTSFIMAPVGALSPVLSVGMFSALMEASIKKPTVNDFMNAQDDISSIKSIYKNRLLKVGLIFVLASAGGAIGNIIGGIELFKNLI
>NZ_CP042217.1|WP_153246994.1|80071_81703_-|peptide-ABC-transporter-substrate-binding-protein
MKKRTMLSFFFVSMLVLILGACNGKEGTKNNSKSKEVEQVATFSAMTPVQSLDPATAVDQTSITLLANVMEGLYRLDEKNQPQPAIAAGQPKISNNGKTYIIVIRDGAKWADGTDITADDFVTAWQRVVDPKTASPSVELFSAIKNAKEIASGKQSKETLAVKSNGNKTIEIELEKPTPYFTDLLAITAYYPVQQKAIKEYGKDYGTSQKSIVTNGAFNLTSLEGVGTSDKWTISKNKEYWDQKEVSMEKINFQVVKEINTGINLYNDGQLDDTPVTGEYAKQYKDNKEFSTTLMANTMYLELNQREKNSILKNKNVRKAISYAIDRSNYAKNILDNGSISAVGVVAKDVAFDPSTKKDFANKMLVHFDTEKAQSYWNKAKKELNIKEQVTLNILTNEEETTKKAAEYIQGQLEENLKGLKITITPVPANVQIERVMKHDFTISLSGWQADYPDPMSFLGNFESNSVLNFGGYSNTKYDEYLKDTSDKRWKSLKKAEELLLEDAGVVPFLQVGNSKLLKSTMRNIEMHSIGAKYDYKKMKRLE
>NZ_CP042217.1|WP_002365953.1|79111_80071_+|conjugal-transfer-protein-TraA
MFLYELFKEQRKLYNFTQEEFYEGIFKKRAASSFEVHNTHDLKVKDLPVLSDRSMMSILEIIHYAKEEFISPYDEDLNSLFDIFQNNTEKENKDYIYKLYKKSIELKEHSIIYWNLYLIIKIQCSEYDSRIVPTDSQDLSELKKMILSKQKFTLYDYKIVTNLSLVFSYKELQPFLSSLFPLDSNAPTVTSEAAYYLLENITTKLVQNRDFESCTEVLNIYNDLLQKFPSYKYKLNYLITYNLVGYFLTNNMDSLNNSIKYVDLLGDLENVELAKLMKDNIYLMISKKNNGSMSKPDTLLTKENNHIKLNEKKITKRLE
>NZ_CP042217.1|WP_011109599.1|78860_78929_-|sex-pheromone-inhibitor-determinant
MSKRAMKKIIPLITLFVVTLVG
>NZ_CP042217.1|WP_002365954.1|77936_78293_-|hypothetical-protein
MSCFSVLRIEHVGYYGNRIIVFGQREKRKLPNATSKFVRKTKTYRIEGMFAVQIEKYFKGKKLCEREVGQVPLRSVYKQIKHVYDHNGVLIARRNSPSGPLKVTGRGMSKFLDYDKKS
>NZ_CP042217.1|WP_002403278.1|77049_77355_-|hypothetical-protein
MTKKEQSIWRKEMLALMNEDADWYRNEDTERFKRIQELAKKIETASTRQFSSHISKERFEAYQRMGLQFKEIAEEFNITTTALQQWRKDNGYPIYNKNNRK
>NZ_CP042217.1|WP_002372553.1|74366_77039_-|surface-exclusion-protein-SEA1/PrgA
MKKFASTGLSILVATGVAGIGGNEVKAAEQTQPKTPENSSTEQPAVKATQTTEQAITEKQQQVTEKQAIVDQKQQVADTAKKEKDAIDQSVKDQQAVVNQNKDALDQSQQAVTDQQAVVDEAKKVVDEATPSAIEKAKDQVATDTQAVDDQQKVVDQAQTDVNQQQAVVDEKAKETNAAKVQNEKDQQAVTAAKQEQAKLEELAKNAEAEKAKAEKEQAAKEAELAKKQKEEAKAKDQKTKDDQAVADQQTVVTTSQEKVADAKADTAAKQADLTAKENALKDKQAATKQAQNTLDSSKEELKGHKGINLPANFTPDYYKKLSEQEKQAMEKEALALNKVFPENQADAAKATEMINVKNPTEKQKQQMSDYVVGLINDVREKLGLQKLKISNQAMKFAWDVAKYDNPKEFDHDVNAINRAAKENGFKEFPGQNFYENLSMGRFTTQEGKVSMYDFEKAARNALVSMLMNDGHSGYSHLDSLLDANETNMAVSISGDLNDISAKIHIISYNQSKLVETNTYEEGTAPVFKSKETLQKEVATNQEKLATAQQVESDAQQARSASQQALNTAKTTQATAEKELSVHKATLANLQAVATKSTTNYEEKVRQTATAEKSLQQTKDQLATINELIQNRAAVLEKAKTNVAEAQAIEQTSAKVLKEKQEAQKAEEKTLNSLKEVLNLAEENLNQKQVALKTSTRSLARLENAQPTYEKAVNELNKAEAAVVQAKEAYENSLKSLEELKEQQAVATLSYTQAQEDLSNAKLELQQYQGVLRDLEAQQAEQRRQEALQEQVAKEQQRLEREAKQQQMLVASATSADKTPGLQQLSFSKQKEQPKAQTLTHSEPRKTKQVAKAQESLPHTGEQKSIWLTIFGLFMAVGAISFKNKRRKNS
>NZ_CP042217.1|WP_002369734.1|74109_74295_-|hypothetical-protein
MAKKINLVSIFCSHEALEQIYILSYPYCLIKQYLFKRIEDIFGSFFIGEMTLLWRNRSRLK
>NZ_CP042217.1|WP_011109609.1|73998_74091_-|hypothetical-protein
MFYLIMQGANPCQQVGFTVNDPDCRLAKTV
>NZ_CP042217.1|WP_002382053.1|85248_85590_+|hypothetical-protein
MTENRKPSLIGNRNKNLYQETPRPEQPYSGAETIPKDILANERGTIRVPLDQKIEFDALLATSEYHYTYELMAELVYEAVKNKTKEENKKYQETLAMLREKELKKIERKKMKK
>NZ_CP042217.1|WP_002403282.1|85748_86045_-|hypothetical-protein
MPRKTFVYPHPINAYIIKQLGITVEEFCELHAFSQGTVSSWITRNKKIETLPISFIYSLSLSASQTMDQVYSDLLKLQDDYLLHLEHHRRTKKIIDER
>NZ_CP042217.1|WP_153246995.1|86284_86395_-|type-I-toxin-antitoxin-system-Fst-family-toxin
MLFVKDSMSLVIAPIFVGLVLEMISRVLDEEDDNRK
>NZ_CP042217.1|WP_002394802.1|86889_87207_+|heavy-metal-binding-domain-containing-protein
MLITTSEKLYGVEYETLDVVFGVTTHSKNIVKNIGAGLKNLVGGEIKAYTEMQQEARKIAMDRLKEEAKNIGADAIIAMRFDSGSISNDMQSVVAYGTAVKFKNQ
>NZ_CP042217.1|WP_002354485.1|87483_88170_+|IS6-like-element-IS1216-family-transposase
MTMNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHTTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLNNLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLLGIPA
>NZ_CP042217.1|WP_010711268.1|88365_88962_+|recombinase-family-protein
MSIYGYSRVSTSNQDYKTQIQKLEQAGAEKIFSEKYTGTKKEGRKELEELLSIVKPDDKVLVTKIDRLARSIVDLNSIISSLNNSGVTITFLDNALTFEPNKSDSMQTLMMNMLGSFAQFERDLIVTRTQEGKQWHRANNKNYREGRPKRVLNDKYKHALELMETNSMREVEKKTGISLSTLKRIKKQAKEEQLLSEK
>NZ_CP042217.1|WP_002394798.1|88978_89263_+|hypothetical-protein
MENREKIIQLLENPLISGYGIEKMSNGRLYSANFQRYKKRVAKEKQPMVIFDTMSVKVEKLLLELTEEVLRVQPKTKQEYREMVARYSFRNGEN
>NZ_CP042217.1|WP_002394799.1|89264_89498_+|hypothetical-protein
MVVRKKYDYWGIEITTWNKTNVVAYVACDCGQLARRELGKYNHFKCSSCKKEYKLSNGSYVEIRTKKELKKGKILIK
>NZ_CP042217.1|WP_002354485.1|89573_90260_+|IS6-like-element-IS1216-family-transposase
MTMNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHTTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLNNLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLLGIPA
>NZ_CP042217.1|WP_153246996.1|90341_90818_+|CPBP-family-intramembrane-metalloprotease
MNIIKTNHPFLTKKNILIILVATLIDRGIAIGGTLLLNMQGHTTTANDSTLIKLFSGVSPVLVVLLLGIAAPIMEEIVFRGGIIGYLVENNALLAILISSFLFGIIHGPTNFISFGMYFFMGIILSVSYYKTKDLRVSISIHFLNNLFPAIAIAYGLI

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP042217_1	1.1\|84228\|56\|NZ_CP042217\|CRISPRCasFinder	84228-84283	56	MH830363	Enterococcus faecalis plasmid p1, complete sequence	62829-62884	0	1.0
NZ_CP042217_1	1.1\|84228\|56\|NZ_CP042217\|CRISPRCasFinder	84228-84283	56	NZ_CP042217	Enterococcus faecalis strain L8 plasmid pL8, complete sequence	84228-84283	0	1.0
NZ_CP042217_1	1.1\|84228\|56\|NZ_CP042217\|CRISPRCasFinder	84228-84283	56	NZ_CP022486	Enterococcus faecalis ARO1/DG plasmid pARO1.3, complete sequence	13563-13618	0	1.0
NZ_CP042217_1	1.1\|84228\|56\|NZ_CP042217\|CRISPRCasFinder	84228-84283	56	NC_014726	Enterococcus faecalis plasmid pTW9, complete sequence	5433-5488	0	1.0
NZ_CP042217_1	1.1\|84228\|56\|NZ_CP042217\|CRISPRCasFinder	84228-84283	56	NZ_CP028721	Enterococcus faecalis strain CVM N48037F plasmid pN48037F-1, complete sequence	25936-25991	1	0.982

1. spacer 1.1|84228|56|NZ_CP042217|CRISPRCasFinder matches to MH830363 (Enterococcus faecalis plasmid p1, complete sequence) position: , mismatch: 0, identity: 1.0

gtgtaaaaaaacattgattatttaaattgtctattgtataatttaagtatagagat	CRISPR spacer
gtgtaaaaaaacattgattatttaaattgtctattgtataatttaagtatagagat	Protospacer
********************************************************

2. spacer 1.1|84228|56|NZ_CP042217|CRISPRCasFinder matches to NZ_CP042217 (Enterococcus faecalis strain L8 plasmid pL8, complete sequence) position: , mismatch: 0, identity: 1.0

gtgtaaaaaaacattgattatttaaattgtctattgtataatttaagtatagagat	CRISPR spacer
gtgtaaaaaaacattgattatttaaattgtctattgtataatttaagtatagagat	Protospacer
********************************************************

3. spacer 1.1|84228|56|NZ_CP042217|CRISPRCasFinder matches to NZ_CP022486 (Enterococcus faecalis ARO1/DG plasmid pARO1.3, complete sequence) position: , mismatch: 0, identity: 1.0

gtgtaaaaaaacattgattatttaaattgtctattgtataatttaagtatagagat	CRISPR spacer
gtgtaaaaaaacattgattatttaaattgtctattgtataatttaagtatagagat	Protospacer
********************************************************

4. spacer 1.1|84228|56|NZ_CP042217|CRISPRCasFinder matches to NC_014726 (Enterococcus faecalis plasmid pTW9, complete sequence) position: , mismatch: 0, identity: 1.0

gtgtaaaaaaacattgattatttaaattgtctattgtataatttaagtatagagat	CRISPR spacer
gtgtaaaaaaacattgattatttaaattgtctattgtataatttaagtatagagat	Protospacer
********************************************************

5. spacer 1.1|84228|56|NZ_CP042217|CRISPRCasFinder matches to NZ_CP028721 (Enterococcus faecalis strain CVM N48037F plasmid pN48037F-1, complete sequence) position: , mismatch: 1, identity: 0.982

-gtgtaaaaaaacattgattatttaaattgtctattgtataatttaagtatagagat	CRISPR spacer
tgtgt-aaaaaacattgattatttaaattgtctattgtataatttaagtatagagat	Protospacer
 **** ***************************************************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 50974

Streptococcus_phage(52.17%)

integrase,transposase,holin

attL 1:60|attR 41005:41594

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1:60	attL	NA	NA	NA	NA
WP_096638011.1\|1240_1357_-	zeta-toxin	NA	NA	NA	NA
WP_002333004.1\|2202_3816_-	hypothetical protein	NA	NA	NA	NA
WP_002326774.1\|3839_4721_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	2.3e-22	30.2
WP_002326773.1\|5031_5628_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_153246986.1\|5712_6210_-	molecular chaperone DnaJ	NA	NA	NA	NA
WP_002326830.1\|6734_7052_-	hypothetical protein	A0A1W6JN36	Lactococcus_phage	3.5e-26	79.4
WP_087285024.1\|7548_8586_+\|transposase	IS1595-like element ISSag10 family transposase	NA	NA	NA	NA
WP_002837187.1\|8609_9104_+	lincosamide nucleotidyltransferase Lnu(C)	A0A2K5B286	Erysipelothrix_phage	2.1e-49	55.5
WP_153246987.1\|9242_9749_-	zeta-toxin	NA	NA	NA	NA
WP_153246988.1\|10867_13477_-	Cna B-type domain-containing protein	NA	NA	NA	NA
WP_080486621.1\|13685_14150_-	AAA family ATPase	NA	NA	NA	NA
WP_000301765.1\|14151_14424_-	antitoxin	A0A1X9I6E5	Streptococcus_phage	5.0e-05	100.0
WP_001835296.1\|14441_14657_-	peptide-binding protein	A0A1X9I6D5	Streptococcus_phage	4.2e-31	97.1
WP_002326827.1\|14748_15645_-	ParA family protein	A0A1X9I765	Streptococcus_phage	1.1e-152	97.9
WP_099780263.1\|16041_16173_-	hypothetical protein	E4ZFP9	Streptococcus_phage	5.7e-15	95.3
WP_002321849.1\|16177_16915_-	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B)	E4ZFQ0	Streptococcus_phage	3.7e-135	100.0
WP_013641314.1\|17039_17123_-	23S rRNA methyltransferase attenuator leader peptide ErmL	NA	NA	NA	NA
WP_000635249.1\|17171_17411_-	peptide-binding protein	A0A1X9I6D5	Streptococcus_phage	6.8e-22	81.5
WP_153246989.1\|17551_19696_-	DNA topoisomerase III	A0A1X9I6W8	Streptococcus_phage	1.7e-265	97.3
WP_153246990.1\|19695_20058_-	recombinase family protein	NA	NA	NA	NA
WP_153246991.1\|20139_20826_+\|transposase	IS6-like element IS1216 family transposase	A0A1X9I6C6	Streptococcus_phage	5.9e-127	99.1
WP_096710548.1\|21651_26022_-	restriction endonuclease	A0A1V0SEE0	Indivirus	3.0e-22	27.7
WP_010721123.1\|26014_26761_-	N-6 DNA methylase	A0A1D8KTL9	Synechococcus_phage	2.8e-05	29.1
WP_001092058.1\|27355_28018_-	methyltransferase domain-containing protein	A0A1X9I6N4	Streptococcus_phage	5.9e-07	30.3
WP_002360844.1\|28408_29140_+	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A)	E4ZFQ0	Streptococcus_phage	2.3e-60	51.9
WP_000067268.1\|29264_30047_-	aminoglycoside nucleotidyltransferase ANT(9)-Ia	NA	NA	NA	NA
WP_153246992.1\|30726_32694_-	ABC-F type ribosomal protection protein OptrA	A0A2K9L3Z8	Tupanvirus	1.8e-51	28.5
WP_002360186.1\|33024_34179_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_002300186.1\|35571_36657_-\|integrase	tyrosine-type recombinase/integrase	A0A2I7SCV1	Paenibacillus_phage	4.0e-13	33.9
WP_096710565.1\|36775_37096_-	DNA recombinase	NA	NA	NA	NA
WP_096710566.1\|37440_37695_-	hypothetical protein	NA	NA	NA	NA
WP_002370267.1\|37823_38036_-	hypothetical protein	NA	NA	NA	NA
WP_010721127.1\|38065_38689_-	recombinase family protein	M9Q1K0	Clostridium_phage	1.8e-13	30.1
WP_000774078.1\|38959_39472_-	hypothetical protein	NA	NA	NA	NA
WP_000357244.1\|39478_39997_-	YfbU family protein	NA	NA	NA	NA
WP_153246997.1\|40158_40389_-	hypothetical protein	NA	NA	NA	NA
WP_002354485.1\|40542_41229_+\|transposase	IS6-like element IS1216 family transposase	A0A1X9I6C6	Streptococcus_phage	2.0e-127	99.6
WP_000406546.1\|41641_42283_-	hypothetical protein	NA	NA	NA	NA
41005:41594	attR	NA	NA	NA	NA
WP_002383787.1\|42664_43978_-	hypothetical protein	NA	NA	NA	NA
WP_000865436.1\|44101_44965_-	DNA/RNA non-specific endonuclease	NA	NA	NA	NA
WP_153246993.1\|44954_45398_-	hypothetical protein	NA	NA	NA	NA
WP_002367766.1\|45611_46547_-	hypothetical protein	NA	NA	NA	NA
WP_001031355.1\|46688_46886_-	hypothetical protein	NA	NA	NA	NA
WP_002365924.1\|47361_47604_+\|holin	putative holin-like toxin	NA	NA	NA	NA
WP_000615486.1\|47822_48299_-	single-stranded DNA-binding protein	A0A1S5PRS2	Streptococcus_phage	8.8e-21	49.5
WP_002372583.1\|48438_49779_-	PcfJ	A8ATM0	Listeria_phage	1.9e-97	42.0
WP_000347505.1\|49769_50546_-	hypothetical protein	A8ATL9	Listeria_phage	2.5e-17	44.6
WP_001245899.1\|50707_50974_-	hypothetical protein	A0A1W6JN36	Lactococcus_phage	2.0e-22	68.2

DBSCAN-SWA_2

60939 : 61398

Lactococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002365911.1\|60939_61398_-	single-stranded DNA-binding protein	Q9B008	Lactococcus_phage	6.6e-42	59.2

DBSCAN-SWA_3

65019 : 66291

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010711028.1\|65019_66291_-	CHAP domain-containing protein	A0A1P8CMP9	Staphylococcus_phage	7.6e-11	36.2

DBSCAN-SWA_4

73434 : 73770

Enterococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002360910.1\|73434_73770_-	hypothetical protein	F0PIH7	Enterococcus_phage	2.3e-39	69.4

DBSCAN-SWA_5

84297 : 90260

Streptococcus_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002386477.1\|84297_85245_+	AAA family ATPase	F0PIG8	Enterococcus_phage	2.4e-30	34.8
WP_002382053.1\|85248_85590_+	hypothetical protein	NA	NA	NA	NA
WP_002403282.1\|85748_86045_-	hypothetical protein	NA	NA	NA	NA
WP_153246995.1\|86284_86395_-	type I toxin-antitoxin system Fst family toxin	NA	NA	NA	NA
WP_002394802.1\|86889_87207_+	heavy metal-binding domain-containing protein	NA	NA	NA	NA
WP_002354485.1\|87483_88170_+\|transposase	IS6-like element IS1216 family transposase	A0A1X9I6C6	Streptococcus_phage	2.0e-127	99.6
WP_010711268.1\|88365_88962_+	recombinase family protein	A0A0A8WIK3	Clostridium_phage	4.2e-20	37.1
WP_002394798.1\|88978_89263_+	hypothetical protein	NA	NA	NA	NA
WP_002394799.1\|89264_89498_+	hypothetical protein	NA	NA	NA	NA
WP_002354485.1\|89573_90260_+\|transposase	IS6-like element IS1216 family transposase	A0A1X9I6C6	Streptococcus_phage	2.0e-127	99.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP042216

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP042216_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042216_1

438809-439440

TypeII

II-A,II-B

Consensus_repeat	Method
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	PILER-CR
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	CRISPRCasFinder
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	CRT

9 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of NZ_CP042216_1

>merge|NZ_CP042216|1|438809-439440|PILER-CR,CRISPRCasFinder,CRT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAACACTGCTCATTCGTTTTCTCCTCCTAACACGCTGTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAACCAGCGCCGGAAAAGTAGCAAGCCCCACAGTGTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAACACGTGCCTTCAAATCCAAAAAAGGTTTGTTGTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAACTGTTTTAAATTCATACATAACGAAACATGTGTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAACTTAGAAAAGACGTGACAGAGCAAACAGCGCGTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAACAGGTACAATTTATGGATTGTCACATGTCATGTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAACTGATGAAAACCGATGGTATTTACTTTCACAGTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAACCTCGTTAGAATGCCCTTCACAGCTGTTAAAGTTTTAGAGTCATGTTGTTTAGAATGGTACCAAATCTCTAATGAGCATTCATTACATATGTAGAACGTTTTAGAGTCATGTTGTTTAGTTTTCGCAAATACG

>NZ_CP042216|1|1|438809-439374|PILER-CR
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	ACTGCTCATTCGTTTTCTCCTCCTAACACGCT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	CAGCGCCGGAAAAGTAGCAAGCCCCACAGT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	ACGTGCCTTCAAATCCAAAAAAGGTTTGTT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	TGTTTTAAATTCATACATAACGAAACATGT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	TTAGAAAAGACGTGACAGAGCAAACAGCGC
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	AGGTACAATTTATGGATTGTCACATGTCAT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	TGATGAAAACCGATGGTATTTACTTTCACA
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	CTCGTTAGAATGCCCTTCACAGCTGTTAAA
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAATC

>NZ_CP042216|1|1|438809-439440|CRISPRCasFinder
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	ACTGCTCATTCGTTTTCTCCTCCTAACACGCT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	CAGCGCCGGAAAAGTAGCAAGCCCCACAGT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	ACGTGCCTTCAAATCCAAAAAAGGTTTGTT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	TGTTTTAAATTCATACATAACGAAACATGT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	TTAGAAAAGACGTGACAGAGCAAACAGCGC
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	AGGTACAATTTATGGATTGTCACATGTCAT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	TGATGAAAACCGATGGTATTTACTTTCACA
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	CTCGTTAGAATGCCCTTCACAGCTGTTAAA
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAATC	TCTAATGAGCATTCATTACATATGTAGAAC
GTTTTAGAGTCATGTTGTTTAGTTTTCGCAAATACG

>NZ_CP042216|1|1|438809-439440|CRT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	ACTGCTCATTCGTTTTCTCCTCCTAACACGCT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	CAGCGCCGGAAAAGTAGCAAGCCCCACAGT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	ACGTGCCTTCAAATCCAAAAAAGGTTTGTT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	TGTTTTAAATTCATACATAACGAAACATGT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	TTAGAAAAGACGTGACAGAGCAAACAGCGC
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	AGGTACAATTTATGGATTGTCACATGTCAT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	TGATGAAAACCGATGGTATTTACTTTCACA
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	CTCGTTAGAATGCCCTTCACAGCTGTTAAA
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAATC	TCTAATGAGCATTCATTACATATGTAGAAC
GTTTTAGAGTCATGTTGTTTAGTTTTCGCAAATACG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042216.1\|WP_002378012.1\|438055_438715_+\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd09758_csn2_CAS-II-A	gnl\|CDD\|213408
NZ_CP042216.1\|WP_002378009.1\|432848_436862_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
NZ_CP042216.1\|WP_002378020.1\|448022_450209_+\|PBP1A-family-penicillin-binding-protein	unknown	unknown	gnl\|CDD\|273955
NZ_CP042216.1\|WP_002364837.1\|427957_429607_+\|polysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|240529
NZ_CP042216.1\|WP_002364833.1\|437725_438055_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_CP042216.1\|WP_002358655.1\|430583_431999_+\|dipeptidase-PepV	unknown	unknown	gnl\|CDD\|130941
NZ_CP042216.1\|WP_002378021.1\|450768_452004_+\|DNA-repair-exonuclease	unknown	unknown	gnl\|CDD\|277319
NZ_CP042216.1\|WP_002364834.1\|436862_437729_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NZ_CP042216.1\|WP_002401855.1\|444608_446129_+\|phosphoglucomutase	unknown	unknown	gnl\|CDD\|215211
NZ_CP042216.1\|WP_002367997.1\|446139_446694_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|224584
NZ_CP042216.1\|WP_002355509.1\|444119_444575_+\|arginine-repressor	unknown	unknown	gnl\|CDD\|224355
NZ_CP042216.1\|WP_002401854.1\|446817_447669_-\|RluA-family-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|223638
NZ_CP042216.1\|WP_002378005.1\|426227_427754_-\|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L--lysine-ligase	unknown	unknown	gnl\|CDD\|237588
NZ_CP042216.1\|WP_002367993.1\|441506_442460_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224050
NZ_CP042216.1\|WP_002355504.1\|432142_432376_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042216.1\|WP_002358653.1\|425588_426161_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223477
NZ_CP042216.1\|WP_002395370.1\|429676_430450_+\|rRNA-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|224108
NZ_CP042216.1\|WP_002378016.1\|442460_443978_+\|ABC-transporter-permease/substrate-binding-protein	unknown	unknown	gnl\|CDD\|270328
NZ_CP042216.1\|WP_002355518.1\|450271_450613_+\|YlbF-family-regulator	unknown	unknown	gnl\|CDD\|237467
NZ_CP042216.1\|WP_002381241.1\|440257_441271_-\|acyltransferase-family-protein	unknown	unknown	gnl\|CDD\|226122

Protein	Function_ID	Function_description	E-value
NZ_CP042216.1\|WP_002378012.1\|438055_438715_+\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	1.59659e-118
NZ_CP042216.1\|WP_002378009.1\|432848_436862_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
NZ_CP042216.1\|WP_002364834.1\|436862_437729_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	2.59266e-115
NZ_CP042216.1\|WP_002378020.1\|448022_450209_+\|PBP1A-family-penicillin-binding-protein	gnl\|CDD\|273955	TIGR02074, Includes:_Penicillin-insensitive_transglycosylase, penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	0
NZ_CP042216.1\|WP_002364837.1\|427957_429607_+\|polysaccharide-biosynthesis-protein	gnl\|CDD\|240529	cd13124, MATE_SpoVB_like, Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins. The integral membrane protein SpoVB has been implicated in the biosynthesis of the peptidoglycan component of the spore cortex in Bacillus subtilis. This model represents a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	2.27874e-136
NZ_CP042216.1\|WP_002367993.1\|441506_442460_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224050	COG1125, OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism].	4.78143e-140
NZ_CP042216.1\|WP_002358655.1\|430583_431999_+\|dipeptidase-PepV	gnl\|CDD\|130941	TIGR01886, Beta-Ala-Xaa_dipeptidase, dipeptidase PepV. This model represents a small clade of dipeptidase enzymes which are members of the larger M25 subfamily of metalloproteases. Two characterized enzymes are included in the seed. One, from Lactococcus lactis has been shown to act on a wide range of dipeptides, but not larger peptides. The enzyme from Lactobacillus delbrueckii was originally characterized as a Xaa-His dipeptidase, specifically a carnosinase (beta-Ala-His) by complementation of an E. coli mutant. Further study, including the crystallization of the enzyme, has shown it to also be a non-specific dipeptidase. This group also includes enzymes from Streptococcus and Enterococcus. [Protein fate, Degradation of proteins, peptides, and glycopeptides].	0
NZ_CP042216.1\|WP_002364833.1\|437725_438055_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	1.08189e-44
NZ_CP042216.1\|WP_002401855.1\|444608_446129_+\|phosphoglucomutase	gnl\|CDD\|215211	PLN02371, PLN02371, phosphoglucosamine mutase family protein.	0
NZ_CP042216.1\|WP_002367997.1\|446139_446694_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	5.36986e-26
NZ_CP042216.1\|WP_002355509.1\|444119_444575_+\|arginine-repressor	gnl\|CDD\|224355	COG1438, ArgR, Arginine repressor [Transcription].	1.0984e-46
NZ_CP042216.1\|WP_002401854.1\|446817_447669_-\|RluA-family-pseudouridine-synthase	gnl\|CDD\|223638	COG0564, RluA, Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis].	2.48238e-91
NZ_CP042216.1\|WP_002378005.1\|426227_427754_-\|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L--lysine-ligase	gnl\|CDD\|237588	PRK14022, PRK14022, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase.	0
NZ_CP042216.1\|WP_002378016.1\|442460_443978_+\|ABC-transporter-permease/substrate-binding-protein	gnl\|CDD\|270328	cd13610, PBP2_ChoS, Substrate-binding domain ChoS of an osmoregulated ABC-type transporter and related proteins; type 2 periplasmic-binding protein fold. Osmoprotectant binding lipoprotein ChoS of Lactococcus lactis is predicted to be involved in uptake of compatible solutes such as choline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ChoS belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.15846e-168
NZ_CP042216.1\|WP_002395370.1\|429676_430450_+\|rRNA-pseudouridine-synthase	gnl\|CDD\|224108	COG1187, RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis].	5.74514e-92
NZ_CP042216.1\|WP_002358653.1\|425588_426161_+\|hypothetical-protein	gnl\|CDD\|223477	COG0400, COG0400, Predicted esterase [General function prediction only].	4.15912e-18
NZ_CP042216.1\|WP_002378021.1\|450768_452004_+\|DNA-repair-exonuclease	gnl\|CDD\|277319	cd00840, MPP_Mre11_N, Mre11 nuclease, N-terminal metallophosphatase domain. Mre11 (also known as SbcD in Escherichia coli) is a subunit of the MRX protein complex. This complex includes: Mre11, Rad50, and Xrs2/Nbs1, and plays a vital role in several nuclear processes including DNA double-strand break repair, telomere length maintenance, cell cycle checkpoint control, and meiotic recombination, in eukaryotes. During double-strand break repair, the MRX complex is required to hold the two ends of a broken chromosome together. In vitro studies show that Mre11 has 3'-5' exonuclease activity on dsDNA templates and endonuclease activity on dsDNA and ssDNA templates. In addition to the N-terminal phosphatase domain, the eukaryotic MRE11 members of this family have a C-terminal DNA binding domain (not included in this alignment model). MRE11-like proteins are found in prokaryotes and archaea was well as in eukaryotes. Mre11 belongs to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	9.16125e-50
NZ_CP042216.1\|WP_002355518.1\|450271_450613_+\|YlbF-family-regulator	gnl\|CDD\|237467	PRK13676, PRK13676, YlbF/YmcA family competence regulator.	2.56028e-37
NZ_CP042216.1\|WP_002381241.1\|440257_441271_-\|acyltransferase-family-protein	gnl\|CDD\|226122	COG3594, NolL, Fucose 4-O-acetylase and related acetyltransferases [Carbohydrate transport and metabolism].	2.63008e-11

>NZ_CP042216.1|WP_002378012.1|438055_438715_+|type-II-A-CRISPR-associated-protein-Csn2
MRVNFSLLEEPIEIEKATFLTIKDVQTFAHLVKLIYQYDGENDLKLFDAQQKGLKPTELFVVTDILGYDVNSAATLKLIYGDLEAQLNDKPEVKSMIEKLTGTISQLIGYELLEHEMDLEEDGITVQELFKALGIKIETTSDTIFEKVMEITQVHRYLSKKKLLIFINACTYLTEDEVQQVVEYISLNNVDVLFLEQRVVQNRFQYILDENFYLSYEKA
>NZ_CP042216.1|WP_002364833.1|437725_438055_+|CRISPR-associated-endonuclease-Cas2
MSYRYMRLLLMFDMPTDTASDRKAYRKFRKFLINEGFIMHQFSVYSKILLNDTANKAMLARLKQNNPQRGLITLLNVTEKQFSRMIYLHGEQDNRVANSDERIVFLGEE
>NZ_CP042216.1|WP_002364834.1|436862_437729_+|type-II-CRISPR-associated-endonuclease-Cas1
MGWRTVVVNKHSKLSYKNNHLVFKAIDHQELIHLSEIDVLLLETTDISLTTMLLKRLIDEKILVLFCDDKRLPIGKILPFYGRHDSSLQLTRQLAWTEERKGQVWTAIIAQKITNQSLHLAQRDYGQKAAALLAMRAELRLFDPANREGHAARSYFNTLFGNDFTREQENDINAGLNYGYTLLLSIFARELVQTGCFTQLGLKHANQFNDFNLASDLMEPFRPLVDQIIYENRKEAFPIMKRKLFALFMNTYMYKKKQMFLTNIATDYTKHVVKVLNQEEEGVPEFGI
>NZ_CP042216.1|WP_002378009.1|432848_436862_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MKKDYVIGLDIGTNSVGWAVMTEDYQLVKKKMPIYGNTEKKKIKKNFWGVRLFEEGHTAEDRRLKRTARRRISRRRNRLRYLQAFFEEAMTALDENFFARLQESFLVPEDKKWHRHPIFAKLEDEVAYHETYPTIYHLRKKLADSSEQADLRLIYLALAHIVKYRGHFLIEGKLSTENISVKEQFQQFMIIYNQTFVNGESRLVSAPLPESVLIEEELTEKASRTKKSEKVLQQFPQEKANGLFGQFLKLMVGNKADFKKVFGLEEEAKITYASESYEEDLEGILAKVGDEYSDVFLAAKNVYDAVELSTILADSDKKSHAKLSSSMIVRFTEHQEDLKNFKRFIRENCPDEYDNLFKNEQKDGYAGYITHAGKVSQLKFYQYVKKIIQDIAGAEYFLEKIAQENFLRKQRTFDNGVIPHQIHLAELQAIIHRQAAYYPFLKENQEKIEQLVTFRIPYYVGPLSKGDANTFAWLKRQSEEPIRPWNLQETVDLDQSATAFIERMTNFDTYLPSEKVLPKHSLLYEKFMVFNELTKISYTDDRGIKANFSGKEKEKIFDYLFKTRRKVKKKDIIQFYRNEYNTEIVTLSGLEEDQFNASFSTYQDLLKCGLTRAELDHPDNAEKLEDIIKILTIFEDRQRIRTQLSTFKGQFSAEVLKKLERKHYTGWGRLSKKLINGIYDKESGKTILDYLIKDDGVSKHYNRNFMQLINDSQLSFKNAIQKAQSSEHEETLSETVNELAGSPAIKKGIYQSLKIVDELVAIMGYAPKRIVVEMARENQTTSTGKRRSIQRLKIVEKAMAEIGSNLLKEQPTTNEQLRDTRLFLYYMQNGKDMYTGDELSLHRLSHYDIDHIIPQSFMKDDSLDNLVLVGSTENRGKSDDVPSKEVVKDMKAYWEKLYAAGLISQRKFQRLTKGEQGGLTLEDKAHFIQRQLVETRQITKNVAGILDQRYNAKSKEKKVQIITLKASLTSQFRSIFGLYKVREVNDYHHGQDAYLNCVVATTLLKVYPNLAPEFVYGEYPKFQTFKENKATAKAIIYTNLLRFFTEDEPRFTKDGEILWSNSYLKTIKKELNYHQMNIVKKVEVQKGGFSKESIKPKGPSNKLIPVKNGLDPQKYGGFDSPIVAYTVLFTHEKGKKPLIKQEILGITIMEKTRFEQNPILFLEEKGFLRPRVLMKLPKYTLYQFPEGRRRLLASAKEAQKGNQMVLPEHLLTLLYHAKQCLLPNQSESLAYVEQHQPEFQEILERVVDFAEVHTLAKSKVQQIVKLFEANQTADVKEIAASFIQLMQFNAMGAPSTFKFFQKDIERARYTSIKEIFDATIIYQSTTGLYETRRKVVD
>NZ_CP042216.1|WP_002355504.1|432142_432376_+|hypothetical-protein
MSETLIVNYLIKGRVKMNVEELVQKAKDLIGEGNVEHAQQFIEEHKDELGEHYHKITAMLADTTTDGLFDKIKGLFQ
>NZ_CP042216.1|WP_002358655.1|430583_431999_+|dipeptidase-PepV
MTIDWTKEVEARKDDLLEDLQNLLRINSERDDAQATPEAPFGPGPVAGLKHMLAYGERDGFTVKNVDNYAGHIEYGEGDETLGIFGHMDVVPAGDGWETDPYEPVIKDGKIYARGASDDKGPSMAAYYAMKIIKELGLPVSKKIRFVVGSDEESGWGDMDYYFQHEEAPDFGFSPDAEFPIINGEKGNVTIRLTFRGGNGADYKLESFKSGLRENMVPGTADAVVTAASADEAASLAASFETFIKQEAKISGNAELSDKTVTFHVVGKGAHGASPQSGINAATFLATFLNDYSFAEGAYSFINTIAEFIHEDFYGEKLGVAFEDEKMGKLTMNAGIVNFDPENPENSLVTLNFRYPKGTSAEELQAKVQATVGETVTATQGDRNQEPHYVPVDDPLVATLLQVYEDHTGEKGQEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEFMELDDLFRAAAIYADAIYRLAK
>NZ_CP042216.1|WP_002395370.1|429676_430450_+|rRNA-pseudouridine-synthase
MSQAIFLKERGMTMRLDKFLADVGIGSRKEIKQLLKKKVVTVNGDVVKEAKTQVNEETDQIALMGEILTYQKFFYYMLHKPQGVISATEDQRDETVIDLLTDQDYRADLFPVGRLDKDTEGLLLLTNDGQLAHQLLSPKKHVDKEYLAEVEGLVTAEDCQLFAQGFALKDGEMVKPSRLVIETINEEEGTSVVRLVIQEGKFHQVKRMLATVGKPVTYLKRLRMGELWLDETLELGGYRPLTEAELQQLQPKQSYLN
>NZ_CP042216.1|WP_002364837.1|427957_429607_+|polysaccharide-biosynthesis-protein
MINQPNSVDQPILTNQEKMVKGSAWMTASNIISRMLGAIYIIPWYAWMGEHGNEANSLFSMGYTIYALFLMISTAGIPGAIAKQTSHYNSLNEYKISRQLFYRALQLMGGLGVVFAIVMYLASPALAALSGGGPELVPTMRSLSLAVLVFPSMSVIRGYFQGNQEMMPFALSQIVEQVARVFYMLLTAFIIMKVFEGNYVTAVTQATFAAFIGMLASFAVLGYYMYKQKPLFDYLEEHSANEHEIAPKELLIETFKEAIPFIVVGSGVTVFKLVDQFTFSNFMRLFTDYSDTQLRELFGIFNANPDKLTMIVVALATSISATGLPLITEAVTLKNHRELARLISNNLQLFVFVMLPATFGMIVLAQPLYTVFYMPDALGTSLLVQACYASLFLGLYMLVSNMLMGMYENRDAMRYLGIGLAVKLIVQFPAIRLFEVYGPLLATMIGFTVSCVLILRRIRQVTRFNYKLTLRRTLLMFCITVIMMIIALIFRQFLYLFLDPTRRFQAFIIVVIVAAAGGAFYGYSVLKIRLADRLLGKNAAKLRAKFNIK
>NZ_CP042216.1|WP_002378005.1|426227_427754_-|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L--lysine-ligase
MTISLFAIRDCLEKEDLLKEFISPEGWHLTLSDTLGQREVTALSYDSRDVTAETLFFCKGLNFKEIYLENAVKDGLEIYVSEVPYEVPAQLGIIVTDIKKAMAVLSMAFYDYPQNKLKLIGFTGTKGKTTAAYFTKYILDVATQQKTALLSTMNSTLDGKTFFKSALTTPESLDLYRMMATAVANGMTHFIMEVSSQAYKTNRVYKLFFDVGIFLNITPDHISPIEHPTFDDYFYCKRQLITHSKVIVLNHEADYFPLLKETAQQQKVPAIVYGSQPAPEVDYSFAVSSEDSLRFIVESPADALGLAGSYHLRLGGDFNKGNALSAAIASVLVGASKEECQQGIAATTVPGRMESLTNTNGATVYVDYAHNYDSLKNLLTFVREEHPDGRLIVLVGSTGDKAISRRKDFGRVLSELADVAVLTTDDPASEDPAKICQEIQAHITKEMPVYTILDRGEAIAHALSLSTTADDAIVLAGKGADLYQKVNGVDEPYAGDFALAEAFINKKN
>NZ_CP042216.1|WP_002358653.1|425588_426161_+|hypothetical-protein
MKQFFQKGSKPNQLVVAFHGTGGNEYQLLTTIATLYPEASVLSYLGTEGVGEQRRFFAPLVNGALPRANFDERVTAFLEEVWQPQKLYDEVIFIGYSNGANFILGLLEKNPTIANTVILLHPSNLGYQYVSGEFATKVIVTTGAQDELSIPGQVLSLANQLKKHFPVDFLLVDGGHGLSEEEVTKIKEVL
>NZ_CP042216.1|WP_002381241.1|440257_441271_-|acyltransferase-family-protein
MENDKRIYKWDNVKLFLIFLVIFGHILDREASPSRLMETINFWIYSFHMPAFIFVSGLFSKHAIKQRKYLRLLSFVWLYLLAKLLITLANFAFANKMNFDLLNETGVPWYLLSLASFYLITIFLQRVQPKIMLPIIIVIGCASGYLPVEGFLSLGRTLGFFPFFYCGYLMDIQKLQTFLDHRKVKWAAIGVILSSFLFVNSQWSLATKFWGFLTGWASYAEISPAFEYSSFIQLFFYVAAALVSLSWFALLPKRKLPLSALGKDTLYPYLLHMPLIILLESGLQLDTLFKEWFTFRILALFFLALFILAITNMPVVKRGADYLFNPQSIMIPKKIYK
>NZ_CP042216.1|WP_002367993.1|441506_442460_+|ABC-transporter-ATP-binding-protein
MIKFQNVSKVYQENAVLSDVNLTIQQGEFFVLVGPSGSGKTTTLKMINRLIEPTTGEVALNEQAVTNYPLRELRLKIGYVLQQIALFPNLTVAENIELIPEMKKWPKEQRRERTIELLKKVQLNPEEYLHRKPAALSGGEQQRIGILRAIAAEPEVILMDEPFSALDPISRHHLQRLVKELHQELASTIVFVTHDMNEALLLGERICIMDAGKIIQVDTPEAIQKHPKNNFVGQFFKQSSPELANYCGADLTAFLEAADETIEPVPTVFMETNLKEIVQLINAQEKANLVEKQQVLGCITSKTITRFMEQLLESEGQ
>NZ_CP042216.1|WP_002378016.1|442460_443978_+|ABC-transporter-permease/substrate-binding-protein
MQALIETFFARKEEYLQALIEHMQLSFISLLFAALIAIPLAIYLTSHRKLAESLLQVTGIFQTIPSLALLGLLIPLIGIGQPPAIVALVIYALFPILQNTYTGLTEIDPSLEEAAEAFGMSKKEKLFKFELQMALPFIISGIRTATVLIIGTATLAALIGAGGLGTFILLGIDRNNLSLIFIGALSSAALAVLFNYGIHWLEKANGRRLIIGGTILGLLLGGSFFWNQQTSSKEKQLTIAGKLGAEPDIIINMYKALIEENSDIQVTLKPNFGKTTFLYNALKSDEIDLYPEFTGTVIETFLKNPPQLDNQPQVVYEAARAGLKKQENLTLLKPMRYENTYAVAVKRSFAKAHQLKTISDLQKISNQLKAGFTLEFIDRQDGYKGLQEKYHLNLNVQSMEPALRYQAINNGEVNVIDAYSTDSELRQYDLVTLEDDQALFPPYQGAPLIKTATLEKYPELAEILNKLAGKISEEEMSEMNYQVNVEGQDPSIVAKDYLKEKNLLK
>NZ_CP042216.1|WP_002355509.1|444119_444575_+|arginine-repressor
MKKAERQRLIKQLIMQQEIETQDELITRLEELGVRATQATVSRDIREMSIVKTHGADGRVKYAIFSQAQGTSSEEKLRESVKDSVVRMERVQFIVILHTEMGNADVVSNFLDEVAYPEVAGTVAGADTIIVITRSEEDAEHFIERIENMIF
>NZ_CP042216.1|WP_002401855.1|444608_446129_+|phosphoglucomutase
MVELKALQNGSDIRGIALDTEEQTATLTATAVAEIAVGVVRWLQDKKQLPRKAQQRLTIAIGHDSRLTAEPIKQALVDTFLSLGIQVIDVGLATTPAMFMATQFPTLQCDAAIMITASHLPYYFNGLKFFTAEGGAEKEDIRYILSHTDPLTANENGTLMKQELLPIYAEHLVAKIRQGIHSPEEKPLQGFRIIVDAGNGAGGFFAEQVLQVLGADTTGSQFLEPDGHFPNHVPNPDNSEAMKSIQTAVLANQADLGIIFDTDVDRSAVVDQSGEVLNRNNLIAVLAAIVLKEAPGSYIVTNSPTSSHLKTFIEEKGGQQIRYISGYRNVINKMIELNHGGFQTPLAIETSGHAAFQENYNLDDGAYVVAKILMLLPELKQNNQTLGDLIATLKQPAETNEFRFKITAEDVTCYGQQVLRDFELFVESQADFAVDRENQEGVRGNVSGQYGSGWFLLRLSLHEPLLVLQVENDQSDKNACVIEKIATFLQKYEEIDSQQIENNLGN
>NZ_CP042216.1|WP_002367997.1|446139_446694_+|GNAT-family-N-acetyltransferase
MENVLKGKHIGFSHFREEYIEHIAKQQWDNELLRHLSWDALHPWGLEEWKDFTINKGEDDRFLFAILENTTEEFIGWVSLSDVQLKNRGANLGIAILQKEQRGQGYGFEAVSLICKFAFYELGLHKIRLAVNSNNQKAIHVYEKVGFKKEGIDREALFQDGQWLDIYNYGILQKEWLQMIKAES
>NZ_CP042216.1|WP_002401854.1|446817_447669_-|RluA-family-pseudouridine-synthase
MRLPENFSTMTVKELLENEWLVPRKVRHFLRTRKNVKINGETAAFHFPVQAGDCVTLTFEETDYVRPTIHLGEATHVKVLYEDEHLMIVNKPYGIKTHPNQPQETDTLLNHVAAYLAEKNQVPYVVHRLDKETSGAIVFAKNPFVLPILGRLLETKQIYRQYQAIVAGHFNQKEQTINQPIGRDRHDRRKRRIDPQKGDSAITHVQVVQALSNNQTAVTCVLETGRTHQIRVHLASEGHPIIGDPLYNPKSQAARLMLHASQLHLLHPFTKKQIVVTAAPGLW
>NZ_CP042216.1|WP_002378020.1|448022_450209_+|PBP1A-family-penicillin-binding-protein
MDNLKQFFSKVGVGLRHFWTWIKPYLIQFHQARKRIWKKYQINKIFLLIGLVVALGASIYLFYLAKSANVETLKSGLSESTRVYDESGEEVGKLFGQKGTFVELDNISPYIQDAVISTEDRGFYQHKGYSIKGIARAVVGKLTFGKIGGGGGGSTITQQLAKNAYLTQEQTLDRKARELFLAIEIEKKYSKKDILAMYLNNSYFGNGVWGVQDAARKYFGVDASQVTVGEAATLAGMLKGPGIYNPIDYIDNATARRNTVLQLMVDNKKLSQEEANQEASVNLASLLNDTYVGDENSYKYPYYFDAVIDEAVNRYKFKEEDILNKGYKIYTSLNQGYQDAMDATYKNDALFPPNAEDGAMVQSGSVAIDPKTGGVQALVGGRGEHVYRGFNFATQTKRSPGSSLKPISVYTPALEAGYKPDSVLEDKPQDYYPAQNYSRTYSGEVPMYQALGESLNLPAVWLLHQIGLDKGYEKTEKFGIPLSEKDRYYGLALGGLQTGVSPLTMAGAYSAFANEGYKTETHLITKIVDSTGAIVVDNTKVKKEQVITKDVADGITSMLLGVFSSGSGVNAQPAGYVMAGKTGTTETNFDSSKTNDQWVIGYTPEVVIATWLGFQETSKTHYLEGSSATYASQVFNSQASGILPQVKQAQFPVADAYATGGKVVDSNDSLTGGANSNWRDNLKDFGNSVQDGASNFGDTLNEVGGQIKDGAKKVKDKIEGIFGGLLGN
>NZ_CP042216.1|WP_002355518.1|450271_450613_+|YlbF-family-regulator
MSNIYDTANQIERELRELDEFKALQAAYEEVKADEAAYTLFKEFQGFQQGLQEKQMRGEEFTDEDAEKAQSIATKVQETAVINELMQKEQAFSLVVNDLNRIIMTPVRDMYND
>NZ_CP042216.1|WP_002378021.1|450768_452004_+|DNA-repair-exonuclease
MKLLHTADLHMDRSFEGLTGIPTALAKRLREANQQLLMNIVTVAIREAVDLVIFAGDTFHQSQTSISMQAQLMAALEQLKQAEIPVILTFGNHDYYKKDRYWFSFPDNVFLFEKEMVETLYFETRAGEQVAVSGFSYEHPWIDENKALEFPIKQADSDIHIGIYHGDTSRKAQQNYAPFTWKDLKATGYNYWALGHIHQPQIVSEQPLIVYPGTPQGHTKKEQSLQGVAVVTLSQNQATVQFEKVAEIDWTNEEVSLAQCRDTQSVLSYLETSLLTKWHAHQQQQLMALTLKETQHLDVTVVQAIVNGELLSYLQQQLLQKTQGDFFVYRLILQAEEPTKEPIYLSASPNLLTALEKTYLDPVIFEDTTKELLRYPEFAGIFSMDEQWRSESLRLAHEQINEDFTIQEDPL

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Crispr_ID: NZ_CP042216_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042216_2

1786710-1787141

Orphan

II-A,II-B

Consensus_repeat	Method
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CRISPRCasFinder
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CRT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	PILER-CR

6 spacers

The CRISPR arrays of NZ_CP042216_2

>merge|NZ_CP042216|2|1786710-1787141|CRISPRCasFinder,CRT,PILER-CR
GTGATAGTTTGTTTTTTAACAACATGGCTCTAAAACAAATTTTTTGAACTTAATGCAATTTCTTGAGTTTTGGTACCATTCTAAACAACATGACTCTAAAACAAAACTTTTGACGGCTCTTTAGTCAACCCAGTTTTGGTACCATTCTAAACAACATGACTCTAAAACGGAGAAATGTAGCTGCTGTTTTGACATTAGGTTTTGGTACCATTCTGAACAACATGACTCTAAAACTGTTTCATCGTCCTTTCTATTTGGGAAGTGGTTTTGGTACCATTCTAAACAACATGACTCTAAAACTTCTATTCTTGCCTTTGCCTTTAAATTAGCGTTTTGGTACCATTCTAAACAACATGACTCTAAAACTTAGATCTAACTAATTGCAAAGTTTTTTTTGTTTTGGTACCATTCTAAACAACATGACTCTAAAAC

>NZ_CP042216|2|2|1786710-1787141|CRISPRCasFinder
GTGATAGTTTGTTTTTTAACAACATGGCTCTAAAAC	AAATTTTTTGAACTTAATGCAATTTCTTGA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	AAAACTTTTGACGGCTCTTTAGTCAACCCA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	GGAGAAATGTAGCTGCTGTTTTGACATTAG
GTTTTGGTACCATTCTGAACAACATGACTCTAAAAC	TGTTTCATCGTCCTTTCTATTTGGGAAGTG
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	TTCTATTCTTGCCTTTGCCTTTAAATTAGC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	TTAGATCTAACTAATTGCAAAGTTTTTTTT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC

>NZ_CP042216|2|2|1786710-1787141|CRT
GTGATAGTTTGTTTTTTAACAACATGGCTCTAAAAC	AAATTTTTTGAACTTAATGCAATTTCTTGA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	AAAACTTTTGACGGCTCTTTAGTCAACCCA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	GGAGAAATGTAGCTGCTGTTTTGACATTAG
GTTTTGGTACCATTCTGAACAACATGACTCTAAAAC	TGTTTCATCGTCCTTTCTATTTGGGAAGTG
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	TTCTATTCTTGCCTTTGCCTTTAAATTAGC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	TTAGATCTAACTAATTGCAAAGTTTTTTTT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC

>NZ_CP042216|2|2|1786776-1787141|PILER-CR
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	AAAACTTTTGACGGCTCTTTAGTCAACCCA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	GGAGAAATGTAGCTGCTGTTTTGACATTAG
GTTTTGGTACCATTCTGAACAACATGACTCTAAAAC	TGTTTCATCGTCCTTTCTATTTGGGAAGTG
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	TTCTATTCTTGCCTTTGCCTTTAAATTAGC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	TTAGATCTAACTAATTGCAAAGTTTTTTTT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042216.1\|WP_002369164.1\|1774309_1776733_-\|DNA-translocase-FtsK	unknown	unknown	gnl\|CDD\|224588
NZ_CP042216.1\|WP_002364369.1\|1782136_1783870_-\|thiol-reductant-ABC-exporter-subunit-CydD	unknown	unknown	gnl\|CDD\|274323
NZ_CP042216.1\|WP_002360016.1\|1778286_1779192_-\|prenyltransferase	unknown	unknown	gnl\|CDD\|235695
NZ_CP042216.1\|WP_002356962.1\|1792155_1793394_+\|multidrug-efflux-MFS-transporter	unknown	unknown	gnl\|CDD\|340949
NZ_CP042216.1\|WP_002356976.1\|1783874_1784888_-\|cytochrome-d-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|376764
NZ_CP042216.1\|WP_002356974.1\|1784884_1786303_-\|cytochrome-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|376587
NZ_CP042216.1\|WP_002356961.1\|1793367_1793517_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042216.1\|WP_002360017.1\|1777046_1778258_-\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224172
NZ_CP042216.1\|WP_002360015.1\|1779313_1780294_+\|polyprenyl-synthetase-family-protein	unknown	unknown	gnl\|CDD\|223220
NZ_CP042216.1\|WP_100781779.1\|1786462_1786561_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042216.1\|WP_002388224.1\|1788246_1790328_-\|DNA-topoisomerase-III	unknown	unknown	gnl\|CDD\|236078
NZ_CP042216.1\|WP_002356965.1\|1790921_1791491_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379115
NZ_CP042216.1\|WP_016627602.1\|1780373_1782140_-\|thiol-reductant-ABC-exporter-subunit-CydC	unknown	unknown	gnl\|CDD\|227320
NZ_CP042216.1\|WP_002356959.1\|1794923_1795268_-\|DUF1831-domain-containing-protein	unknown	unknown	gnl\|CDD\|370163
NZ_CP042216.1\|WP_002356958.1\|1795335_1796481_-\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|224029
NZ_CP042216.1\|WP_002356960.1\|1793573_1794698_-\|tRNA-2-thiouridine(34)-synthase-MnmA	unknown	unknown	gnl\|CDD\|234664
NZ_CP042216.1\|WP_002372057.1\|1787298_1788162_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NZ_CP042216.1\|WP_002356963.1\|1791623_1792139_+\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	unknown	unknown	gnl\|CDD\|176643
NZ_CP042216.1\|WP_002356966.1\|1790458_1790824_-\|DUF1033-family-protein	unknown	unknown	gnl\|CDD\|336361
NZ_CP042216.1\|WP_153246939.1\|1776838_1776970_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP042216.1\|WP_002369164.1\|1774309_1776733_-\|DNA-translocase-FtsK	gnl\|CDD\|224588	COG1674, FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning].	1.01564e-174
NZ_CP042216.1\|WP_002364369.1\|1782136_1783870_-\|thiol-reductant-ABC-exporter-subunit-CydD	gnl\|CDD\|274323	TIGR02857, transport_ATP-binding_protein, thiol reductant ABC exporter, CydD subunit. The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD.	0
NZ_CP042216.1\|WP_002360016.1\|1778286_1779192_-\|prenyltransferase	gnl\|CDD\|235695	PRK06080, PRK06080, 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated.	8.82053e-105
NZ_CP042216.1\|WP_002356962.1\|1792155_1793394_+\|multidrug-efflux-MFS-transporter	gnl\|CDD\|340949	cd17391, MFS_MdtG_MDR_like, Multidrug resistance protein MdtG and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli multidrug resistance protein MdtG, Streptococcus pneumoniae multidrug resistance efflux pump PmrA, and similar multidrug resistance (MDR) transporters from bacteria. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtG confers resistance to fosfomycin and deoxycholate. PmrA serves as an efflux pump for various substrates and is associated with fluoroquinolone resistance. MdtG-like MDR transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.18762e-174
NZ_CP042216.1\|WP_002388224.1\|1788246_1790328_-\|DNA-topoisomerase-III	gnl\|CDD\|236078	PRK07726, PRK07726, DNA topoisomerase 3.	0
NZ_CP042216.1\|WP_002356974.1\|1784884_1786303_-\|cytochrome-ubiquinol-oxidase-subunit-I	gnl\|CDD\|376587	pfam01654, Cyt_bd_oxida_I, Cytochrome bd terminal oxidase subunit I. This family are the alternative oxidases found in many bacteria which oxidize ubiquinol and reduce oxygen as part of the electron transport chain. This family is the subunit I of the oxidase E. coli has two copies of the oxidase, bo and bd', both of which are represented here In some nitrogen fixing bacteria, e.g. Klebsiella pneumoniae this oxidase is responsible for removing oxygen in microaerobic conditions, making the oxidase required for nitrogen fixation. This subunit binds a single b-haem, through ligands at His186 and Met393 (using SW:P11026 numbering). In addition His19 is a ligand for the haem b found in subunit II.	0
NZ_CP042216.1\|WP_002360017.1\|1777046_1778258_-\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224172	COG1252, Ndh, NADH dehydrogenase, FAD-containing subunit [Energy production and conversion].	1.24993e-121
NZ_CP042216.1\|WP_002360015.1\|1779313_1780294_+\|polyprenyl-synthetase-family-protein	gnl\|CDD\|223220	COG0142, IspA, Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism].	2.52576e-80
NZ_CP042216.1\|WP_002356965.1\|1790921_1791491_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|379115	pfam13305, WHG, WHG domain. This presumed domain is around 80 amino acids in length. It is found to the C-terminus of a DNA-binding helix-turn-helix domain. This domain may be involved in binding to an as yet unknown ligand that allows a transcriptional regulation response to that molecule. The domain is named WHG after three conserved residues near the C-terminus of the domain.	2.91104e-15
NZ_CP042216.1\|WP_016627602.1\|1780373_1782140_-\|thiol-reductant-ABC-exporter-subunit-CydC	gnl\|CDD\|227320	COG4987, CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones].	0
NZ_CP042216.1\|WP_002356959.1\|1794923_1795268_-\|DUF1831-domain-containing-protein	gnl\|CDD\|370163	pfam08866, DUF1831, Putative amino acid metabolism. Solution of the structure of the Lactobacillus plantarum protein from this family has indicated a potential new fold with remote similarities to TBP-like (TATA-binding protein) structures. This similarity, in combination with genomic context analysis, leads us to propose an involvement in amino-acid metabolism. The potentially novel fold is an alpha + beta fold comprising two beta sheets packed against a single helix. The enzyme is present in the cytosol.	1.33245e-53
NZ_CP042216.1\|WP_002356958.1\|1795335_1796481_-\|cysteine-desulfurase	gnl\|CDD\|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	4.17386e-179
NZ_CP042216.1\|WP_002356960.1\|1793573_1794698_-\|tRNA-2-thiouridine(34)-synthase-MnmA	gnl\|CDD\|234664	PRK00143, mnmA, tRNA-specific 2-thiouridylase MnmA; Reviewed.	0
NZ_CP042216.1\|WP_002372057.1\|1787298_1788162_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	2.55306e-27
NZ_CP042216.1\|WP_002356963.1\|1791623_1792139_+\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	gnl\|CDD\|176643	cd00865, PEBP_bact_arch, PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea. PhosphatidylEthanolamine-Binding Proteins (PEBPs) are represented in all three major phylogenetic divisions (eukaryotes, bacteria, archaea). The members in this subgroup are present in bacterial and archaea. Members here include Escherichia coli YBHB and YBCL which are thought to regulate protein phosphorylation as well as Sulfolobus solfataricus SsCEI which inhibits serine proteases alpha-chymotrypsin and elastase. Although their overall structures are similar, the members of the PEBP family have very different substrates and oligomerization states (monomer/dimer/tetramer). In a few of the bacterial members present here the dimerization interface is proposed to form the ligand binding site, unlike in other PEBP members.	5.73504e-32
NZ_CP042216.1\|WP_002356966.1\|1790458_1790824_-\|DUF1033-family-protein	gnl\|CDD\|336361	pfam06279, DUF1033, Protein of unknown function (DUF1033). This family consists of several hypothetical bacterial proteins. Many of the sequences in this family are annotated as putative DNA binding proteins but the function of this family is unknown.	4.62165e-64
NZ_CP042216.1\|WP_002356976.1\|1783874_1784888_-\|cytochrome-d-ubiquinol-oxidase-subunit-II	gnl\|CDD\|376764	pfam02322, Cyt_bd_oxida_II, Cytochrome bd terminal oxidase subunit II. This family consists of cytochrome bd type terminal oxidases that catalyze quinol-dependent, Na+-independent oxygen uptake. Members of this family are integral membrane proteins and contain a protohaem IX centre B558. One member of the family, Klebsiella pneumoniae CydB, is implicated in having an important role in micro-aerobic nitrogen fixation in the enteric bacterium Klebsiella pneumoniae. The family forms an integral functional unit with subunit I, family Bac_Ubq_Cox, pfam01654.	9.60464e-103

>NZ_CP042216.1|WP_100781779.1|1786462_1786561_-|hypothetical-protein
MIEEREEILGAPKKIVRNASVLFGFCLRKLYT
>NZ_CP042216.1|WP_002356974.1|1784884_1786303_-|cytochrome-ubiquinol-oxidase-subunit-I
MFDIVTLARIQFAMTTVFHFFFVPFSIGLALVVAIMETMYVVKKEERYRKMAKFWGNIFLLSFAVGVVTGIIQEFQFGMNWSDYSRFVGDIFGAPLAVEALLAFFLESTFLGLWIFTWDKMNPKVHVTFIWLVVFGSMMSAFWILVANSFMQHPVGYVINNGRAEMVDFVAVISNPKVWYEFSHVIMGAFTLGGMAVAGMAAFQLLKKRDISFHKASMRIGLWVTLFGSIGVLLAGDLQMKALIEGQPMKFAAMEGAYEDSDDPAAWTLIAWADEREHKQVFGIDIPYMLSILSYNKLSGSVDGMDTVNKRLVEKYGDDKNYYPPVNTLFWSFRIMAGFGALMLLVAALGLFFTRKKKPSLYEKKWMLWIVALCTFAPFLANTTGWLVTELGRYPWTVYGLFTIEQSVSPNVSVASLITSNVIYFLLFAGLGSVMVYLVILELRKGPDYEAKKLAKENEPALDPFDKGVFGE
>NZ_CP042216.1|WP_002356976.1|1783874_1784888_-|cytochrome-d-ubiquinol-oxidase-subunit-II
MSTLQLLWFVLIGVLFSGFFFLEGFDFGVGMAVQTLAHNDDEKDQVVATIGPVWDGNEVWLLTAGGAMFASFPYWYASLFSGYYLILFTILFGLIIRGVSFEFRHNMPEGKRRRMWNWTLSIGSFLVPFFFGILFISLVQGMPLDANGNMHAQFTDYFNLFSIVGGVALTLLCYLHGMNYIALKTEGPIRERARNYAEILYGVLYVGLVVFAVLMYFKTDFYEKNFAVTLILTLAIVVLTVIANVGVFKRKEMLAFLASGLTLVVLVALLFSGLFPRVMIGSEGFDLLIKDATSTPYTLKIMTWISLSILPFVLAYTAWSYYIFRKRISQTAVPEGY
>NZ_CP042216.1|WP_002364369.1|1782136_1783870_-|thiol-reductant-ABC-exporter-subunit-CydD
MIDKDILQMPKIKKILVLLAGFSFLQAVFIIGQAFFLSKAIVGLWSGGHLNQQLQSILLFFIFYLGRHVITYFRERMLDTFSYERSKELREQLLTKIFRLGPNVVQKNGTGNMVTMALEGISQTENYLQLILTKMMNMMIIPWIILAFVFTQDIRSGVTLLIVFPIIIIFMIVLGYAAQSKADKQYAAFQMLSNHFIDSLRGIDTLKLFGLSKKYAGSIYHTSERFRKATMSTLKIAILSTFALDFFTTLSVAVVAVFLGLSLLNGTILLFPALVTLILAPEFFLPIRDFSSDYHATLDGKNSFQAIQAVLALPEAEQTDVLTLDDWHQESQLSVTALNFSYEDATQEAIQSLQFSVDGRKKIGIIGASGSGKSTLINLLSGFLLPTEETSQLAINGQTIPHFLQKDWQKQILYIPQAPYIFQDTLANNIRFYTPEATDEAIQQAIQLVGLDELVKDLPEGIHTLIGESGRMLSGGQAQRVALARAFVDQKRHVLLFDEPTAHLDIETEVEMKERMLPLMNNHLVFFATHRLHWMEEMDYILVMEKGQLVEQGTLAELIEKDGYYVQLMKQMRGGRQ
>NZ_CP042216.1|WP_016627602.1|1780373_1782140_-|thiol-reductant-ABC-exporter-subunit-CydC
MMEKQPTTKDVWKNDQWVRPFLKRYKKTLYFALLLGFLTFFSAGALMFTSGYLISRAASLPENILLIYIPIVLTRAFGIGRPVFRYVERLTSHNWVLKMTSDLRLKLYNVLEKDAIFFKTKYRTGDILGLLSEDINHIQNLYLRTIFPTVIAWILYIFLVIALGFFSWWFALCMLLMLGVVVFLLPLVSVLVNGARQEKHKYAKNELYQTLTDNILGVSDWVFSQRGSEFVARYETDEANVRALDEKMKQFNRGRDFVLQLLFGVIAIAVLAWTSVRFPGNHGGAANWIGAFVLTVFPLIDAFAPLPAAAQETTIYKDSIRRFNELPEGEDDSTEAPVQPNGTSLSIEHLSFAYENQEKKVLNDLSLTIPEKQKLAILGRSGSGKSTLASLIRGDLRPTSGEILLGNIPTEAFGETMTEYIGVMHQAPYLFRTTILNNIRIGREEASEAEVWAVLEKVGLKEMVTQLPEGLQTMVDEAGLRFSGGERHRLALARILLQDTPIVLLDEPTTGLDPITEQQLLETFFEALKDKTVIWITHHLQGVTLMDQVIFIEDGQLEMSGTPEELLATNAHYQKLYRIDRGISSFEE
>NZ_CP042216.1|WP_002360015.1|1779313_1780294_+|polyprenyl-synthetase-family-protein
MNTFWKSFPDVERSLTETCELIEQTLHTRNEDIEEALVTLARSGGKLLRPAFFFLFAQLGDEEKQEKQQLLKIAASLEILHMATLIHDDIIDDSPLRRGAVTIQSQYGKDVAVYTGDLLFTEFFTLIADAMNGSEFMKINAQGMKRLLLGELDQMSHRFDRRMSIPAYLRSVNGKTAELFSLSCLEGAYFGHSSKEVQRLAKRIGRHIGIAFQVYDDILDYTADTETLKKPALEDLSQGVYTLPLLFAYQAAPDVFSPYLDKGRAITLEEAAEVAALVNDYHGVTEAQAFAKKVTNKAITDIQQLPDGTAKETLLSLTELLLHRSF
>NZ_CP042216.1|WP_002360016.1|1778286_1779192_-|prenyltransferase
MNREIFFELVELKAKTASVLPFLLGICFSWYQYGRLHVGYVLIFFIAMFIFNMAVDILDNYNDYHHATEVHDYKEKTNIIGRENLSLPLIRKMIFWMILVSALMGIGLSFIVGWPLLIMGLYCYLIGIFYSSGPKPLSSLPLGEVFSGFTMGFMITLICVYINTFEVFNWSAANLWGIFLVALPNTCYIANLMLANNICDLEEDENNKRYTLVHYLGKASSLKLFVGLNTIAMLAILLAVGLGLTPPTMLLMLLTLPFVRKQTQALLKEQVKSKTFVCAVKILAVGATAQVLFFAIGLWWL
>NZ_CP042216.1|WP_002360017.1|1777046_1778258_-|NAD(P)/FAD-dependent-oxidoreductase
MNKKHVVILGAGYAGLKTLRELQKGAKDVEITLVDRNNYHYEATDLHEVAAGTQPAEKITYNIMDVVDEKMTTFIQGTVKTIDAATQTVALEDGQTINYDYLVVSLGFESESFGIPGVQEHALQMVDVKTALNVYEHIQEQMRQYKATQNEEFLKIVVCGAGFTGIELLGSLVENKPKFAEIAGVSADQIQIYCVEAVTRLLPMFNEKLANYGVQLLKDSAIHLLLGKPIKEIKPGAVVYQDNEAGDLAELSAKTIIWTTGVSGSHVVGDSGFEARRGRVMVQPDLTDANHSNVYIIGDCSAVMDTETNRPYPTTAQIALKMGAHAAKNIQAQLKGEATKPFSFKSQGSVCSVGNTRALGIVGKTDIKGYPASFMKKIIMNKALFETGGTKEMMAKGRFDLYH
>NZ_CP042216.1|WP_153246939.1|1776838_1776970_-|hypothetical-protein
MLFNFWRISDYFRRSWFCSRRLSVFEGGAKIQSDFCPTLIFLK
>NZ_CP042216.1|WP_002369164.1|1774309_1776733_-|DNA-translocase-FtsK
MAQKRATNKKKSTTKKKTKKQQQQQERLNYMFLGLIFILFGVFGLFRLGFLGTLLANCLRLVVGNTFPFAAILLILYGLLVMIYGKDFPLKRGRPIFGAVLIYISVLLFFHAFMFRNVSGSQPDILGNTWEFLQSDLKANQVTQNVGGGMIGALLYQGTYFLVAQFGSYLIATLLLLAGIFLMSMWDFQQIVDHFQSIQDRLSHVSAKSQARQEEKEAKRAAKKEAKAAERQAKIEAAAQQKLQERERMEQAAAERLTKTPVETHQPMVEEPAAPTPVQIDSFQQQNQAMPVPPIAATKPQREQEEEAADEAGVLEFEISEEAEDRDYQLPPTDLLDTIQATDQSGEYEKIEKNIGVLEQTFKSFGVDAKVVKASLGPSVTKFEVQPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNSAISTVSFRDIVEAQPSHPDKLLEVPLGRDISGMVQTADLSKMPHLLIAGSTGSGKSVAINGIITGILMQAKPHEVKLMMIDPKMVELNVYNGIPHLLTPVVTNPRKAAQALQKVVQEMEFRYEKFAATGVRNITGYNQLIQQKNAEDGENRPILPFIVVIVDELADLMMVASNEVEDAIIRLAQMARAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDTNGAEKLLGRGDMLFLPMGENKPIRIQGAFISDQEVERVVAFVTDQQEAEYQESMMPTDEPTTSGGGEAPQDELFEEAKNLVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVIGPSEGSKPRKVFLQAESEEAAPETPEQ
>NZ_CP042216.1|WP_002372057.1|1787298_1788162_-|AraC-family-transcriptional-regulator
MLANLNQAMDYIEEHLTEEVSFDELAKKTGISVYHFKRTFSFVAGMSLAEYIKKRRLAEANLALLAGEKVTDVAFKYGYQSIEGFSRAFRDWTGQAPSEVMKTQIQKTFPKFSFYIDIKGGQSMDVKLIEKPAFQIVGVSQKVPLQYQGENQAIIELAQRITPQQRAEMHTFDDVYPHQVVNASFDFQEGRTTEGGEMTHMIGFVTSQENTYEDLEQLSVPAHTWAVFPNEGPFPQTLQETWARIFSEWLPSSGYQVVAAPEISFTQYQGPAEAKYSEIWLAVTATK
>NZ_CP042216.1|WP_002388224.1|1788246_1790328_-|DNA-topoisomerase-III
MVAKQLIIAEKPSVAKDLSRVLGANQKNKNYYEGPNVIVTWALGHLLGLKMPEDLNKEWQTWQMETLPMIPKNLGIKPLPKTGHQLKAIKQLANRKDVSEAVIATDAGREGELVARWILEYVRFNKPVKRLWISSQTDKAIKDGFKKIRPAKDYDNLYYSALARAKADWLVGLNVTRALTVKYQDNLSAGRVQTPTLAMVRQQEKTIEQFKPQTYFTISLTVESEKAKMTQKNPYALKERQEAEQLVKELSKQKGLVTDIQEKVKTENAPLPYDLTEIQREANQRFQFSAKKTLSLVQSLYETHKIVSYPRTDSKYLTTDMKGTMKERLQAIADFSPEVKGYLKNGAVVKQQKVFQNAKVTDHHGLIPTEQRPRYEKLSNDEQKIYQMIVQRFLGLFAEPNQTKQTKVTVAFGKETFVFHQNKVVVAGWKTTAEQPLSTVQWQKGMTVAPNFTINKELTSPPKPLTEGTLLGKMEKHSLGTPATRAEIIEKLIKSELMERTNSGLSVSAKGKQLLDLVNPSLVTPELTEKWEKSLEAIASGQQKSQLFLKDIEEDTKKLVREIKQSEKKYQDFSITQKKCPDCGSNLREKNTKDGKIYVCTNQECSYRRRKDPKVSNHRCPQCHKKMVIIEGKNGRSFKCKFCSITEKIPDKKERKQKMTKHEERRLMKKYSQPDEPEESALAQALKAAMNQE
>NZ_CP042216.1|WP_002356966.1|1790458_1790824_-|DUF1033-family-protein
MYQVITMYGDNEPWWFFDDWQEDIVQEKTFDNLTDAETYYVEVWQKLSQNYTYVNTKPNYLTAFWNDGEERWCEECDEDLQQYFGLALLENHHAVTFENKAEFTTISNHFGKTKFCKRKVI
>NZ_CP042216.1|WP_002356965.1|1790921_1791491_-|TetR/AcrR-family-transcriptional-regulator
MAKKRNLTKAKILESARNLAEELGVQQLTFQNLAVDLGIKYPSLYNHFKNIAEVKNALVDLLIQELNDALRRALVGKSGAEAIRIYAETYQQFAFENSAVYELLISVPKTQNQQLIEGIHETNQIILQLLAFYPFNNEERLHKSRELRSLIHGYITLRFLGYFQREEATPEESYRRMIEDFIASLEVAG
>NZ_CP042216.1|WP_002356963.1|1791623_1792139_+|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein
MHITNRSHLADRYGKRTSAEFLLHERPILSFPISLAAIPKEARYLSWELIDYDTIPLIGFPFIHWLAANVPVTNEIPEDFSRTALKPTIQGKNSLASPLGKQMIPALATETLPELTERYLGLSPRSGVHTYTLYVYATKNPLNLKEGFFANELHQALNDQLLAKAKFEFLY
>NZ_CP042216.1|WP_002356962.1|1792155_1793394_+|multidrug-efflux-MFS-transporter
MYELIKSKIFRPRQPWEKNLLVLWFGTFMAGIGFSLVMPFMPLYINTLGTFTHQQLNFWSGITFSSTFLVTTIVSPWWGRLADRKGRKLMLLRASLGMAIVISLMGAVTSVYQLIGLRLLQGVFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTLLGPLLGGVTASIFGYRPTFFITGTILLLVFVLSLVFVHEEFVPIEKNQAASGKQILKKLEHPHVILGMFITTLIIQASNNSISPIISLYIQQLLGGHGNVTLISGVIASIPGIATLIAAPRFGRLGDRIGSERILTIGLILAIFVYLPMAFVQNVWQLAMLRFLVGISDACLLPAVQTLITRYSPSDAAGRIFSYNQSFQATGNVIGPMIGSSVSAAFGYRGVFISTSCLVLINLLWVRRSTAELKKEKNDD
>NZ_CP042216.1|WP_002356961.1|1793367_1793517_-|hypothetical-protein
MLVVKPVNIRFSFLFYMPIFFKIRKREKLKIQIVDNFSVYNLVIIFLFF
>NZ_CP042216.1|WP_002356960.1|1793573_1794698_-|tRNA-2-thiouridine(34)-synthase-MnmA
MADNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDTDENGVCTATEDYKDVAKVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRLGRTPNPDVMCNKEIKFKAFLDYAMQLGADYVATGHYAQVETDENGVVHMLRGIDNNKDQTYFLSQLSQAQLAKTMFPLGGMEKSEVRAIADRAGLATAKKKDSTGVCFIGEKNFKEFLSNYLPAKKGNMVTEDGEIKGQHDGLMYYTIGQRQGLGIGGGGKTQEPWFVIGKDLTTNTLYVGQGFHHEKLYATHLEASEVHFTVDTPMPKEFDCTAKFRYRQADIPVHVSLSEDGTKATVTFKEPARAVTPGQAVVFYDGMECLGGGLIDRAYQDEKELQYV
>NZ_CP042216.1|WP_002356959.1|1794923_1795268_-|DUF1831-domain-containing-protein
MAFTTTAAVEGSTVFYKVHPSAKRYTLKDNGFTETKSGNFQLIRSLDPTPQRNEGFKLKITITADLKELKMSITTANGLKPMNIFKNEQHEMSKEKYFFLMDGLISRGVLEKVE
>NZ_CP042216.1|WP_002356958.1|1795335_1796481_-|cysteine-desulfurase
MEPIYLDHAATTPLHPTVIQAMTENMQTTFGNPSSIHQFGRKAHGLLEEVRQTIAESLQAKPHEIIFNSGGTEGDNTAILAVAFSRQKEGKHIITTAIEHPAVLRTMEYLETLGFEVTYLPVNENGQISMDQFKKSLREETILVSMMYGNNEIGNRLPIAEVGAILKNHSAIFHTDAVQAYGSEVILPHELGIDLLSISAHKINGPKGVGFLFKSDAIQLPPLLHGGEQEEKRRAGTENLAGIIGMGTAVSLLTSAEKQARKTAYQSFQTIILKALEEANIDFSINGEPTNRLAHVLNLHLKGVPSDLLLMHLDLRGIAISTGSACTAGTVDPSHVLTAMYGENSSAIKESIRISFGYGNTPEEIATFSEVLVAVIQQLKK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP042216_2	2.3\|1786878\|30\|NZ_CP042216\|CRISPRCasFinder,CRT,PILER-CR	1786878-1786907	30	NZ_CP041739	Enterococcus faecalis EnGen0107 strain B594 plasmid p1, complete sequence	39957-39986	0	1.0
NZ_CP042216_2	2.3\|1786878\|30\|NZ_CP042216\|CRISPRCasFinder,CRT,PILER-CR	1786878-1786907	30	NZ_CP030043	Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence	37120-37149	0	1.0
NZ_CP042216_2	2.3\|1786878\|30\|NZ_CP042216\|CRISPRCasFinder,CRT,PILER-CR	1786878-1786907	30	NZ_CP030046	Enterococcus faecalis strain C54 plasmid pC54, complete sequence	53177-53206	0	1.0
NZ_CP042216_2	2.3\|1786878\|30\|NZ_CP042216\|CRISPRCasFinder,CRT,PILER-CR	1786878-1786907	30	NZ_CP022484	Enterococcus faecalis ARO1/DG plasmid pARO1.1, complete sequence	35711-35740	1	0.967
NZ_CP042216_2	2.3\|1786878\|30\|NZ_CP042216\|CRISPRCasFinder,CRT,PILER-CR	1786878-1786907	30	NZ_CP036248	Enterococcus faecalis R712 plasmid pR712_02, complete sequence	48629-48658	1	0.967
NZ_CP042216_2	2.3\|1786878\|30\|NZ_CP042216\|CRISPRCasFinder,CRT,PILER-CR	1786878-1786907	30	NZ_CP042217	Enterococcus faecalis strain L8 plasmid pL8, complete sequence	41683-41712	1	0.967
NZ_CP042216_2	2.3\|1786878\|30\|NZ_CP042216\|CRISPRCasFinder,CRT,PILER-CR	1786878-1786907	30	NZ_MK140641	Enterococcus faecalis strain E035 plasmid pE035, complete sequence	53005-53034	1	0.967
NZ_CP042216_2	2.3\|1786878\|30\|NZ_CP042216\|CRISPRCasFinder,CRT,PILER-CR	1786878-1786907	30	NZ_CP015884	Enterococcus faecalis strain sorialis plasmid Efsorialis-p1, complete sequence	44693-44722	3	0.9
NZ_CP042216_2	2.1\|1786746\|30\|NZ_CP042216\|CRISPRCasFinder,CRT	1786746-1786775	30	NZ_LR214986	Mycoplasma cynos strain NCTC10142 plasmid 13	726854-726883	5	0.833
NZ_CP042216_1	1.4\|439045\|30\|NZ_CP042216\|PILER-CR,CRISPRCasFinder,CRT	439045-439074	30	NZ_CP043436	Campylobacter fetus subsp. venerealis NCTC 10354 plasmid p3226, complete sequence	10209-10238	6	0.8
NZ_CP042216_1	1.4\|439045\|30\|NZ_CP042216\|PILER-CR,CRISPRCasFinder,CRT	439045-439074	30	NZ_CP014570	Campylobacter fetus subsp. venerealis strain 01/165 plasmid mp2, complete sequence	14813-14842	6	0.8
NZ_CP042216_1	1.4\|439045\|30\|NZ_CP042216\|PILER-CR,CRISPRCasFinder,CRT	439045-439074	30	NZ_CP008809	Campylobacter fetus subsp. fetus 04/554 plasmid pCFF04554, complete sequence	2921-2950	6	0.8
NZ_CP042216_1	1.4\|439045\|30\|NZ_CP042216\|PILER-CR,CRISPRCasFinder,CRT	439045-439074	30	NZ_CP008812	Campylobacter fetus subsp. venerealis 97/608 plasmid pCFV97608-2, complete sequence	10382-10411	6	0.8
NZ_CP042216_1	1.7\|439243\|30\|NZ_CP042216\|PILER-CR,CRISPRCasFinder,CRT	439243-439272	30	NZ_CP009691	Bacillus mycoides strain ATCC 6462 plasmid pBMX_1, complete sequence	40757-40786	6	0.8
NZ_CP042216_2	2.1\|1786746\|30\|NZ_CP042216\|CRISPRCasFinder,CRT	1786746-1786775	30	NC_019526	Enterobacteria phage vB_KleM-RaK2, complete genome	41998-42027	6	0.8
NZ_CP042216_2	2.1\|1786746\|30\|NZ_CP042216\|CRISPRCasFinder,CRT	1786746-1786775	30	MT708547	Klebsiella phage Muenster, complete genome	164106-164135	6	0.8
NZ_CP042216_2	2.1\|1786746\|30\|NZ_CP042216\|CRISPRCasFinder,CRT	1786746-1786775	30	AB897757	Klebsiella phage K64-1 DNA, complete genome	42006-42035	6	0.8
NZ_CP042216_2	2.6\|1787076\|30\|NZ_CP042216\|CRISPRCasFinder,CRT,PILER-CR	1787076-1787105	30	NC_009705	Yersinia pseudotuberculosis IP 31758 plasmid p_153kb, complete sequence	35536-35565	6	0.8
NZ_CP042216_1	1.9\|439375\|30\|NZ_CP042216\|CRISPRCasFinder,CRT	439375-439404	30	NZ_CP031270	Staphylococcus warneri strain 16A plasmid unnamed1, complete sequence	9754-9783	7	0.767
NZ_CP042216_1	1.9\|439375\|30\|NZ_CP042216\|CRISPRCasFinder,CRT	439375-439404	30	NZ_CP031270	Staphylococcus warneri strain 16A plasmid unnamed1, complete sequence	20272-20301	7	0.767
NZ_CP042216_2	2.3\|1786878\|30\|NZ_CP042216\|CRISPRCasFinder,CRT,PILER-CR	1786878-1786907	30	NZ_CP023544	Campylobacter jejuni strain CFSAN032806 plasmid pCFSAN032806, complete sequence	42911-42940	7	0.767
NZ_CP042216_2	2.3\|1786878\|30\|NZ_CP042216\|CRISPRCasFinder,CRT,PILER-CR	1786878-1786907	30	NZ_CP017872	Campylobacter coli strain BP3183 plasmid pCCDM183, complete sequence	31018-31047	7	0.767
NZ_CP042216_2	2.3\|1786878\|30\|NZ_CP042216\|CRISPRCasFinder,CRT,PILER-CR	1786878-1786907	30	NC_022355	Campylobacter coli CVM N29710 plasmid pN29710-1, complete sequence	42878-42907	7	0.767
NZ_CP042216_2	2.3\|1786878\|30\|NZ_CP042216\|CRISPRCasFinder,CRT,PILER-CR	1786878-1786907	30	NZ_CP045793	Campylobacter coli strain CFSAN032805 plasmid p1CFSAN032805, complete sequence	32829-32858	7	0.767
NZ_CP042216_2	2.3\|1786878\|30\|NZ_CP042216\|CRISPRCasFinder,CRT,PILER-CR	1786878-1786907	30	NZ_CP023546	Campylobacter coli strain CFSAN032805 plasmid pCFSAN032805_1, complete sequence	33400-33429	7	0.767
NZ_CP042216_2	2.4\|1786944\|30\|NZ_CP042216\|CRISPRCasFinder,CRT,PILER-CR	1786944-1786973	30	NC_019534	Bacteroides fragilis plasmid pBFUK1, complete sequence	7141-7170	7	0.767
NZ_CP042216_2	2.6\|1787076\|30\|NZ_CP042216\|CRISPRCasFinder,CRT,PILER-CR	1787076-1787105	30	MN855587	Siphoviridae sp. isolate 137, complete genome	548-577	7	0.767
NZ_CP042216_1	1.3\|438979\|30\|NZ_CP042216\|PILER-CR,CRISPRCasFinder,CRT	438979-439008	30	NZ_CP010111	Bacillus thuringiensis serovar indiana strain HD521 plasmid pBTHD521-5, complete sequence	134723-134752	8	0.733
NZ_CP042216_1	1.5\|439111\|30\|NZ_CP042216\|PILER-CR,CRISPRCasFinder,CRT	439111-439140	30	NZ_CP053022	Sphingobium yanoikuyae strain YC-XJ2 plasmid p-A-Sy, complete sequence	219326-219355	8	0.733
NZ_CP042216_1	1.5\|439111\|30\|NZ_CP042216\|PILER-CR,CRISPRCasFinder,CRT	439111-439140	30	NZ_CP053224	Sphingobium sp. RSMS plasmid pRSMS1, complete sequence	48396-48425	8	0.733
NZ_CP042216_1	1.5\|439111\|30\|NZ_CP042216\|PILER-CR,CRISPRCasFinder,CRT	439111-439140	30	NZ_CP020539	Sphingobium herbicidovorans strain MH plasmid pMSHV, complete sequence	710636-710665	8	0.733
NZ_CP042216_1	1.9\|439375\|30\|NZ_CP042216\|CRISPRCasFinder,CRT	439375-439404	30	NZ_CP031904	Escherichia coli O104:H4 strain FWSEC0009 plasmid unnamed19, complete sequence	60569-60598	8	0.733
NZ_CP042216_1	1.9\|439375\|30\|NZ_CP042216\|CRISPRCasFinder,CRT	439375-439404	30	NC_018654	Escherichia coli O104:H4 str. 2009EL-2050 plasmid pAA-09EL50, complete sequence	17881-17910	8	0.733
NZ_CP042216_1	1.9\|439375\|30\|NZ_CP042216\|CRISPRCasFinder,CRT	439375-439404	30	NZ_CP023530	Escherichia coli strain FDAARGOS_401 plasmid unnamed, complete sequence	6482-6511	8	0.733
NZ_CP042216_1	1.9\|439375\|30\|NZ_CP042216\|CRISPRCasFinder,CRT	439375-439404	30	NZ_CP041001	Escherichia coli strain FDAARGOS_772 plasmid unnamed1, complete sequence	63459-63488	8	0.733
NZ_CP042216_1	1.9\|439375\|30\|NZ_CP042216\|CRISPRCasFinder,CRT	439375-439404	30	CP025574	Escherichia coli strain E-1246 plasmid pE1246_1, complete sequence	51314-51343	8	0.733
NZ_CP042216_1	1.9\|439375\|30\|NZ_CP042216\|CRISPRCasFinder,CRT	439375-439404	30	NZ_CP023533	Escherichia coli strain FDAARGOS_403 plasmid unnamed2, complete sequence	24355-24384	8	0.733
NZ_CP042216_1	1.9\|439375\|30\|NZ_CP042216\|CRISPRCasFinder,CRT	439375-439404	30	NZ_CP027392	Escherichia coli O104:H4 strain FDAARGOS_349 plasmid unnamed2, complete sequence	4511-4540	8	0.733
NZ_CP042216_1	1.9\|439375\|30\|NZ_CP042216\|CRISPRCasFinder,CRT	439375-439404	30	NZ_CP023062	Escherichia coli strain FORC_069 plasmid pFORC69, complete sequence	55180-55209	8	0.733
NZ_CP042216_1	1.9\|439375\|30\|NZ_CP042216\|CRISPRCasFinder,CRT	439375-439404	30	NZ_CP023552	Escherichia coli strain FORC_043 plasmid pFORC43, complete sequence	47364-47393	8	0.733
NZ_CP042216_1	1.9\|439375\|30\|NZ_CP042216\|CRISPRCasFinder,CRT	439375-439404	30	NZ_KY706108	Escherichia coli strain pAA-ST131 plasmid ESBL20150001, complete sequence	60040-60069	8	0.733
NZ_CP042216_1	1.9\|439375\|30\|NZ_CP042216\|CRISPRCasFinder,CRT	439375-439404	30	NC_011752	Escherichia coli 55989 plasmid 55989p, complete sequence	49973-50002	8	0.733
NZ_CP042216_1	1.9\|439375\|30\|NZ_CP042216\|CRISPRCasFinder,CRT	439375-439404	30	CP042952	Escherichia coli strain D8-1 plasmid pD8-1_1, complete sequence	67474-67503	8	0.733
NZ_CP042216_1	1.9\|439375\|30\|NZ_CP042216\|CRISPRCasFinder,CRT	439375-439404	30	NZ_CP026724	Escherichia coli strain 266917_2 plasmid p266917_2_01, complete sequence	101148-101177	8	0.733
NZ_CP042216_1	1.9\|439375\|30\|NZ_CP042216\|CRISPRCasFinder,CRT	439375-439404	30	CP051693	Escherichia coli strain SCU-318 plasmid pSCU-318-1, complete sequence	31503-31532	8	0.733
NZ_CP042216_1	1.9\|439375\|30\|NZ_CP042216\|CRISPRCasFinder,CRT	439375-439404	30	NC_019000	Escherichia coli plasmid pHUSEC41-2, complete sequence	51056-51085	8	0.733
NZ_CP042216_1	1.9\|439375\|30\|NZ_CP042216\|CRISPRCasFinder,CRT	439375-439404	30	NZ_CP009053	Escherichia coli NCCP15648 plasmid p15648-3, complete sequence	55603-55632	8	0.733
NZ_CP042216_1	1.9\|439375\|30\|NZ_CP042216\|CRISPRCasFinder,CRT	439375-439404	30	NC_018666	Escherichia coli O104:H4 str. 2011C-3493 plasmid pAA-EA11, complete sequence	10746-10775	8	0.733
NZ_CP042216_1	1.9\|439375\|30\|NZ_CP042216\|CRISPRCasFinder,CRT	439375-439404	30	NC_018662	Escherichia coli O104:H4 str. 2009EL-2071 plasmid pAA-09EL71, complete sequence	58558-58587	8	0.733
NZ_CP042216_1	1.9\|439375\|30\|NZ_CP042216\|CRISPRCasFinder,CRT	439375-439404	30	NZ_CP013186	Escherichia coli strain FORC_029 plasmid FORC_029p, complete sequence	39899-39928	8	0.733
NZ_CP042216_1	1.9\|439375\|30\|NZ_CP042216\|CRISPRCasFinder,CRT	439375-439404	30	NZ_CP022087	Escherichia coli O104:H4 strain FDAARGOS_348 plasmid unnamed2, complete sequence	40046-40075	8	0.733
NZ_CP042216_1	1.9\|439375\|30\|NZ_CP042216\|CRISPRCasFinder,CRT	439375-439404	30	CP049615	Escherichia coli O157:H7 strain K1516 plasmid pK1516-3, complete sequence	17811-17840	8	0.733
NZ_CP042216_1	1.9\|439375\|30\|NZ_CP042216\|CRISPRCasFinder,CRT	439375-439404	30	NC_022743	Escherichia coli plasmid pHUSEC2011-2, complete sequence	53979-54008	8	0.733
NZ_CP042216_1	1.9\|439375\|30\|NZ_CP042216\|CRISPRCasFinder,CRT	439375-439404	30	KU886273	Freshwater phage uvFW-CGR-AMD-COM-C455, complete genome	26680-26709	8	0.733
NZ_CP042216_2	2.2\|1786812\|30\|NZ_CP042216\|CRISPRCasFinder,CRT,PILER-CR	1786812-1786841	30	NC_009453	Arthrobacter sp. Rue61a plasmid pAL1, complete sequence	17952-17981	8	0.733
NZ_CP042216_2	2.4\|1786944\|30\|NZ_CP042216\|CRISPRCasFinder,CRT,PILER-CR	1786944-1786973	30	NZ_CP034946	Enterococcus faecium strain NM213 plasmid unnamed3, complete sequence	4703-4732	8	0.733
NZ_CP042216_2	2.4\|1786944\|30\|NZ_CP042216\|CRISPRCasFinder,CRT,PILER-CR	1786944-1786973	30	MT188223	Acinetobacter phage vB_AbaM_D22, complete genome	95957-95986	8	0.733
NZ_CP042216_1	1.1\|438845\|32\|NZ_CP042216\|PILER-CR,CRISPRCasFinder,CRT	438845-438876	32	NC_020062	Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence	1915425-1915456	10	0.688

1. spacer 2.3|1786878|30|NZ_CP042216|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP041739 (Enterococcus faecalis EnGen0107 strain B594 plasmid p1, complete sequence) position: , mismatch: 0, identity: 1.0

ggagaaatgtagctgctgttttgacattag	CRISPR spacer
ggagaaatgtagctgctgttttgacattag	Protospacer
******************************

2. spacer 2.3|1786878|30|NZ_CP042216|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP030043 (Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence) position: , mismatch: 0, identity: 1.0

ggagaaatgtagctgctgttttgacattag	CRISPR spacer
ggagaaatgtagctgctgttttgacattag	Protospacer
******************************

3. spacer 2.3|1786878|30|NZ_CP042216|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP030046 (Enterococcus faecalis strain C54 plasmid pC54, complete sequence) position: , mismatch: 0, identity: 1.0

ggagaaatgtagctgctgttttgacattag	CRISPR spacer
ggagaaatgtagctgctgttttgacattag	Protospacer
******************************

4. spacer 2.3|1786878|30|NZ_CP042216|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022484 (Enterococcus faecalis ARO1/DG plasmid pARO1.1, complete sequence) position: , mismatch: 1, identity: 0.967

ggagaaatgtagctgctgttttgacattag	CRISPR spacer
gaagaaatgtagctgctgttttgacattag	Protospacer
*.****************************

5. spacer 2.3|1786878|30|NZ_CP042216|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP036248 (Enterococcus faecalis R712 plasmid pR712_02, complete sequence) position: , mismatch: 1, identity: 0.967

ggagaaatgtagctgctgttttgacattag	CRISPR spacer
gaagaaatgtagctgctgttttgacattag	Protospacer
*.****************************

6. spacer 2.3|1786878|30|NZ_CP042216|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP042217 (Enterococcus faecalis strain L8 plasmid pL8, complete sequence) position: , mismatch: 1, identity: 0.967

ggagaaatgtagctgctgttttgacattag	CRISPR spacer
gaagaaatgtagctgctgttttgacattag	Protospacer
*.****************************

7. spacer 2.3|1786878|30|NZ_CP042216|CRISPRCasFinder,CRT,PILER-CR matches to NZ_MK140641 (Enterococcus faecalis strain E035 plasmid pE035, complete sequence) position: , mismatch: 1, identity: 0.967

ggagaaatgtagctgctgttttgacattag	CRISPR spacer
gaagaaatgtagctgctgttttgacattag	Protospacer
*.****************************

8. spacer 2.3|1786878|30|NZ_CP042216|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP015884 (Enterococcus faecalis strain sorialis plasmid Efsorialis-p1, complete sequence) position: , mismatch: 3, identity: 0.9

ggagaaatgtagctgctgttttgacattag	CRISPR spacer
gaagaaaggtagctgctgttttaacattag	Protospacer
*.***** **************.*******

9. spacer 2.1|1786746|30|NZ_CP042216|CRISPRCasFinder,CRT matches to NZ_LR214986 (Mycoplasma cynos strain NCTC10142 plasmid 13) position: , mismatch: 5, identity: 0.833

aaattttttgaacttaatgcaatttcttga	CRISPR spacer
aaattttttgctcttaatgcaattacatta	Protospacer
**********  ************ * * *

10. spacer 1.4|439045|30|NZ_CP042216|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP043436 (Campylobacter fetus subsp. venerealis NCTC 10354 plasmid p3226, complete sequence) position: , mismatch: 6, identity: 0.8

tgttttaaattcatacataacgaaacatgt-	CRISPR spacer
tgttttaaattcatccataac-atttatatt	Protospacer
************** ****** *  .**.*

11. spacer 1.4|439045|30|NZ_CP042216|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014570 (Campylobacter fetus subsp. venerealis strain 01/165 plasmid mp2, complete sequence) position: , mismatch: 6, identity: 0.8

tgttttaaattcatacataacgaaacatgt-	CRISPR spacer
tgttttaaattcatccataac-atttatatt	Protospacer
************** ****** *  .**.*

12. spacer 1.4|439045|30|NZ_CP042216|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP008809 (Campylobacter fetus subsp. fetus 04/554 plasmid pCFF04554, complete sequence) position: , mismatch: 6, identity: 0.8

tgttttaaattcatacataacgaaacatgt-	CRISPR spacer
tgttttaaattcatccataac-atttatatt	Protospacer
************** ****** *  .**.*

13. spacer 1.4|439045|30|NZ_CP042216|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP008812 (Campylobacter fetus subsp. venerealis 97/608 plasmid pCFV97608-2, complete sequence) position: , mismatch: 6, identity: 0.8

tgttttaaattcatacataacgaaacatgt-	CRISPR spacer
tgttttaaattcatccataac-atttatatt	Protospacer
************** ****** *  .**.*

14. spacer 1.7|439243|30|NZ_CP042216|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009691 (Bacillus mycoides strain ATCC 6462 plasmid pBMX_1, complete sequence) position: , mismatch: 6, identity: 0.8

tgatgaaaaccgatggtatttactttcaca	CRISPR spacer
aggtaaaaaccgatggtattttctttcgaa	Protospacer
 *.*.**************** *****. *

15. spacer 2.1|1786746|30|NZ_CP042216|CRISPRCasFinder,CRT matches to NC_019526 (Enterobacteria phage vB_KleM-RaK2, complete genome) position: , mismatch: 6, identity: 0.8

aaattttttgaacttaatgcaat--ttcttga	CRISPR spacer
aaattttttgaacgtaatgccataatcgtt--	Protospacer
************* ****** **  *. **

16. spacer 2.1|1786746|30|NZ_CP042216|CRISPRCasFinder,CRT matches to MT708547 (Klebsiella phage Muenster, complete genome) position: , mismatch: 6, identity: 0.8

aaattttttgaacttaatgcaat--ttcttga	CRISPR spacer
aaattttttgaacgtaatgccataatcgtt--	Protospacer
************* ****** **  *. **

17. spacer 2.1|1786746|30|NZ_CP042216|CRISPRCasFinder,CRT matches to AB897757 (Klebsiella phage K64-1 DNA, complete genome) position: , mismatch: 6, identity: 0.8

aaattttttgaacttaatgcaat--ttcttga	CRISPR spacer
aaattttttgaacgtaatgccataatcgtt--	Protospacer
************* ****** **  *. **

18. spacer 2.6|1787076|30|NZ_CP042216|CRISPRCasFinder,CRT,PILER-CR matches to NC_009705 (Yersinia pseudotuberculosis IP 31758 plasmid p_153kb, complete sequence) position: , mismatch: 6, identity: 0.8

ttagatctaactaattgcaaagtttttttt	CRISPR spacer
cttggtttaactaattgaaaagtttttatt	Protospacer
.* *.*.********** ********* **

19. spacer 1.9|439375|30|NZ_CP042216|CRISPRCasFinder,CRT matches to NZ_CP031270 (Staphylococcus warneri strain 16A plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

tctaatgagcattcattacatatgtagaac	CRISPR spacer
ttaaatgagcattcattacttatatacatt	Protospacer
*. **************** ***.** * .

20. spacer 1.9|439375|30|NZ_CP042216|CRISPRCasFinder,CRT matches to NZ_CP031270 (Staphylococcus warneri strain 16A plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

tctaatgagcattcattacatatgtagaac	CRISPR spacer
ttaaatgagcattcattacttatatacatt	Protospacer
*. **************** ***.** * .

21. spacer 2.3|1786878|30|NZ_CP042216|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023544 (Campylobacter jejuni strain CFSAN032806 plasmid pCFSAN032806, complete sequence) position: , mismatch: 7, identity: 0.767

ggagaaatgtagctgctgttttgacattag	CRISPR spacer
ggaaaagtgtagctgctgttttgatgcttt	Protospacer
***.**.*****************...*

22. spacer 2.3|1786878|30|NZ_CP042216|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP017872 (Campylobacter coli strain BP3183 plasmid pCCDM183, complete sequence) position: , mismatch: 7, identity: 0.767

ggagaaatgtagctgctgttttgacattag	CRISPR spacer
ggaaaagtgtagctgctgttttgatgcttt	Protospacer
***.**.*****************...*

23. spacer 2.3|1786878|30|NZ_CP042216|CRISPRCasFinder,CRT,PILER-CR matches to NC_022355 (Campylobacter coli CVM N29710 plasmid pN29710-1, complete sequence) position: , mismatch: 7, identity: 0.767

ggagaaatgtagctgctgttttgacattag	CRISPR spacer
ggaaaagtgtagctgctgttttgatgcttt	Protospacer
***.**.*****************...*

24. spacer 2.3|1786878|30|NZ_CP042216|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP045793 (Campylobacter coli strain CFSAN032805 plasmid p1CFSAN032805, complete sequence) position: , mismatch: 7, identity: 0.767

ggagaaatgtagctgctgttttgacattag	CRISPR spacer
ggaaaagtgtagctgctgttttgatgcttt	Protospacer
***.**.*****************...*

25. spacer 2.3|1786878|30|NZ_CP042216|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023546 (Campylobacter coli strain CFSAN032805 plasmid pCFSAN032805_1, complete sequence) position: , mismatch: 7, identity: 0.767

ggagaaatgtagctgctgttttgacattag	CRISPR spacer
ggaaaagtgtagctgctgttttgatgcttt	Protospacer
***.**.*****************...*

26. spacer 2.4|1786944|30|NZ_CP042216|CRISPRCasFinder,CRT,PILER-CR matches to NC_019534 (Bacteroides fragilis plasmid pBFUK1, complete sequence) position: , mismatch: 7, identity: 0.767

tgtttcatcgtcctttctatttgggaagtg	CRISPR spacer
cgtttcatcgtcctttcttttttggcgtgg	Protospacer
.***************** *** ** .  *

27. spacer 2.6|1787076|30|NZ_CP042216|CRISPRCasFinder,CRT,PILER-CR matches to MN855587 (Siphoviridae sp. isolate 137, complete genome) position: , mismatch: 7, identity: 0.767

ttagatctaactaattgcaaagtttttttt	CRISPR spacer
caatatcttactaatttcaaagttttttgg	Protospacer
. * **** ******* ***********

28. spacer 1.3|438979|30|NZ_CP042216|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP010111 (Bacillus thuringiensis serovar indiana strain HD521 plasmid pBTHD521-5, complete sequence) position: , mismatch: 8, identity: 0.733

acgtgccttcaaatccaaaaaaggtttgtt	CRISPR spacer
aaacaacttcaaatcctaaaaaggattgta	Protospacer
* ... ********** ******* ****

29. spacer 1.5|439111|30|NZ_CP042216|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053022 (Sphingobium yanoikuyae strain YC-XJ2 plasmid p-A-Sy, complete sequence) position: , mismatch: 8, identity: 0.733

ttagaaaa---gacgtgacagagcaaacagcgc	CRISPR spacer
---gagcgtctgacgtgacagaggaaacagcga	Protospacer
   **. .   ************ ********

30. spacer 1.5|439111|30|NZ_CP042216|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053224 (Sphingobium sp. RSMS plasmid pRSMS1, complete sequence) position: , mismatch: 8, identity: 0.733

ttagaaaa---gacgtgacagagcaaacagcgc	CRISPR spacer
---gagcgtctgacgtgacagaggaaacagcga	Protospacer
   **. .   ************ ********

31. spacer 1.5|439111|30|NZ_CP042216|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020539 (Sphingobium herbicidovorans strain MH plasmid pMSHV, complete sequence) position: , mismatch: 8, identity: 0.733

ttagaaaa---gacgtgacagagcaaacagcgc	CRISPR spacer
---gagcgtctgacgtgacagaggaaacagcga	Protospacer
   **. .   ************ ********

32. spacer 1.9|439375|30|NZ_CP042216|CRISPRCasFinder,CRT matches to NZ_CP031904 (Escherichia coli O104:H4 strain FWSEC0009 plasmid unnamed19, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

33. spacer 1.9|439375|30|NZ_CP042216|CRISPRCasFinder,CRT matches to NC_018654 (Escherichia coli O104:H4 str. 2009EL-2050 plasmid pAA-09EL50, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

34. spacer 1.9|439375|30|NZ_CP042216|CRISPRCasFinder,CRT matches to NZ_CP023530 (Escherichia coli strain FDAARGOS_401 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

35. spacer 1.9|439375|30|NZ_CP042216|CRISPRCasFinder,CRT matches to NZ_CP041001 (Escherichia coli strain FDAARGOS_772 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

36. spacer 1.9|439375|30|NZ_CP042216|CRISPRCasFinder,CRT matches to CP025574 (Escherichia coli strain E-1246 plasmid pE1246_1, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

37. spacer 1.9|439375|30|NZ_CP042216|CRISPRCasFinder,CRT matches to NZ_CP023533 (Escherichia coli strain FDAARGOS_403 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

38. spacer 1.9|439375|30|NZ_CP042216|CRISPRCasFinder,CRT matches to NZ_CP027392 (Escherichia coli O104:H4 strain FDAARGOS_349 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

39. spacer 1.9|439375|30|NZ_CP042216|CRISPRCasFinder,CRT matches to NZ_CP023062 (Escherichia coli strain FORC_069 plasmid pFORC69, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

40. spacer 1.9|439375|30|NZ_CP042216|CRISPRCasFinder,CRT matches to NZ_CP023552 (Escherichia coli strain FORC_043 plasmid pFORC43, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

41. spacer 1.9|439375|30|NZ_CP042216|CRISPRCasFinder,CRT matches to NZ_KY706108 (Escherichia coli strain pAA-ST131 plasmid ESBL20150001, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

42. spacer 1.9|439375|30|NZ_CP042216|CRISPRCasFinder,CRT matches to NC_011752 (Escherichia coli 55989 plasmid 55989p, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

43. spacer 1.9|439375|30|NZ_CP042216|CRISPRCasFinder,CRT matches to CP042952 (Escherichia coli strain D8-1 plasmid pD8-1_1, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

44. spacer 1.9|439375|30|NZ_CP042216|CRISPRCasFinder,CRT matches to NZ_CP026724 (Escherichia coli strain 266917_2 plasmid p266917_2_01, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

45. spacer 1.9|439375|30|NZ_CP042216|CRISPRCasFinder,CRT matches to CP051693 (Escherichia coli strain SCU-318 plasmid pSCU-318-1, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

46. spacer 1.9|439375|30|NZ_CP042216|CRISPRCasFinder,CRT matches to NC_019000 (Escherichia coli plasmid pHUSEC41-2, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

47. spacer 1.9|439375|30|NZ_CP042216|CRISPRCasFinder,CRT matches to NZ_CP009053 (Escherichia coli NCCP15648 plasmid p15648-3, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

48. spacer 1.9|439375|30|NZ_CP042216|CRISPRCasFinder,CRT matches to NC_018666 (Escherichia coli O104:H4 str. 2011C-3493 plasmid pAA-EA11, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

49. spacer 1.9|439375|30|NZ_CP042216|CRISPRCasFinder,CRT matches to NC_018662 (Escherichia coli O104:H4 str. 2009EL-2071 plasmid pAA-09EL71, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

50. spacer 1.9|439375|30|NZ_CP042216|CRISPRCasFinder,CRT matches to NZ_CP013186 (Escherichia coli strain FORC_029 plasmid FORC_029p, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

51. spacer 1.9|439375|30|NZ_CP042216|CRISPRCasFinder,CRT matches to NZ_CP022087 (Escherichia coli O104:H4 strain FDAARGOS_348 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

52. spacer 1.9|439375|30|NZ_CP042216|CRISPRCasFinder,CRT matches to CP049615 (Escherichia coli O157:H7 strain K1516 plasmid pK1516-3, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

53. spacer 1.9|439375|30|NZ_CP042216|CRISPRCasFinder,CRT matches to NC_022743 (Escherichia coli plasmid pHUSEC2011-2, complete sequence) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
caaaatcagcattcattacatatgtaacta	Protospacer
.  *** *******************.

54. spacer 1.9|439375|30|NZ_CP042216|CRISPRCasFinder,CRT matches to KU886273 (Freshwater phage uvFW-CGR-AMD-COM-C455, complete genome) position: , mismatch: 8, identity: 0.733

tctaatgagcattcattacatatgtagaac	CRISPR spacer
ttgggctagtattcattacaaatgtagaac	Protospacer
*. ... **.********** *********

55. spacer 2.2|1786812|30|NZ_CP042216|CRISPRCasFinder,CRT,PILER-CR matches to NC_009453 (Arthrobacter sp. Rue61a plasmid pAL1, complete sequence) position: , mismatch: 8, identity: 0.733

aaaacttttgacggctctttagtcaaccca	CRISPR spacer
gcattttttgacggctctgaagtcaaccgt	Protospacer
. * .*************  ********

56. spacer 2.4|1786944|30|NZ_CP042216|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP034946 (Enterococcus faecium strain NM213 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.733

tgtttcatcgtcctttctatttgggaagtg	CRISPR spacer
tgttttatcgtcctttctatttttttacat	Protospacer
*****.****************    *

57. spacer 2.4|1786944|30|NZ_CP042216|CRISPRCasFinder,CRT,PILER-CR matches to MT188223 (Acinetobacter phage vB_AbaM_D22, complete genome) position: , mismatch: 8, identity: 0.733

tgtttcatcgtcctttctatttgggaagtg	CRISPR spacer
gctttcatcggcctttctatttgtgtttta	Protospacer
  ******** ************ *   *.

58. spacer 1.1|438845|32|NZ_CP042216|PILER-CR,CRISPRCasFinder,CRT matches to NC_020062 (Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence) position: , mismatch: 10, identity: 0.688

actgctcattcgttttctcctcctaacacgct	CRISPR spacer
actgctcattcgtttccccctccgcgaattgc	Protospacer
***************.*.*****  . *.  .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

680092 : 688013

Planktothrix_phage(16.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002355794.1\|680092_681151_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.0e-17	30.1
WP_002361357.1\|681150_682107_+	ATP-binding cassette domain-containing protein	A0A1J0FA64	Only_Syngen_Nebraska_virus	4.2e-06	23.9
WP_002355796.1\|682147_683218_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A288TXV8	Enterococcus_phage	7.6e-89	49.0
WP_002355797.1\|683617_684139_+	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	3.0e-14	33.3
WP_002355798.1\|684252_684453_+	50S ribosomal protein L35	NA	NA	NA	NA
WP_002355799.1\|684513_684873_+	50S ribosomal protein L20	NA	NA	NA	NA
WP_002363280.1\|684919_685270_-	hypothetical protein	NA	NA	NA	NA
WP_002361363.1\|685367_685727_+	DUF1304 domain-containing protein	NA	NA	NA	NA
WP_002361364.1\|685854_686289_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_002378095.1\|686306_686822_+	GrpB family protein	A0A2K5B2B6	Erysipelothrix_phage	7.7e-39	49.1
WP_002378096.1\|686837_688013_-	SulP family inorganic anion transporter	A0A2H4J153	uncultured_Caudovirales_phage	5.1e-86	48.0

DBSCAN-SWA_2

738473 : 792860

Streptococcus_phage(45.65%)

head,terminase,tail,integrase,portal,transposase,protease

attL 759529:759556|attR 794369:794396

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000420682.1\|738473_738788_+	YdcP family protein	A0A1S5SF38	Streptococcus_phage	5.2e-54	100.0
WP_000985015.1\|738803_739190_+	YdcP family protein	A0A1S5SF96	Streptococcus_phage	3.0e-64	100.0
WP_000813488.1\|739218_740604_+	DNA translocase FtsK	A0A1S5SFB5	Streptococcus_phage	1.1e-265	100.0
WP_000879507.1\|740606_740759_+	hypothetical protein	NA	NA	NA	NA
WP_000398284.1\|740781_741987_+	XRE family transcriptional regulator	A0A1S5SEX3	Streptococcus_phage	2.8e-233	100.0
WP_001009056.1\|742029_742251_+	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.3e-31	100.0
WP_000342539.1\|742367_742865_+	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	1.7e-91	100.0
WP_000506270.1\|742839_743346_+	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	8.6e-91	100.0
WP_000331160.1\|743329_745777_+	ATP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	100.0
WP_000804748.1\|745779_747957_+	membrane protein	A0A1S5SF30	Streptococcus_phage	0.0e+00	100.0
WP_000769868.1\|747953_748955_+	peptidase P60	A0A1S5SEZ8	Streptococcus_phage	5.0e-191	100.0
WP_001224318.1\|748951_749884_+	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	3.1e-171	99.4
WP_011058339.1\|750158_750245_+	tetracycline resistance determinant leader peptide	NA	NA	NA	NA
WP_002364936.1\|750260_752180_+	tetracycline resistance ribosomal protection protein Tet(M)	A0A1S5SF82	Streptococcus_phage	0.0e+00	94.5
WP_011860842.1\|752275_752470_+	conjugal transfer protein	D0R0F6	Streptococcus_phage	2.2e-18	64.9
WP_001227347.1\|752529_752883_-	helix-turn-helix transcriptional regulator	A0A1S5SFA6	Streptococcus_phage	1.3e-58	100.0
WP_013670292.1\|753087_753159_+	hypothetical protein	NA	NA	NA	NA
WP_000804885.1\|753387_753810_+	sigma-70 family RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	2.5e-72	100.0
WP_000857133.1\|753806_754037_+	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	2.7e-36	100.0
WP_001845478.1\|754262_754514_-	hypothetical protein	NA	NA	NA	NA
WP_000814511.1\|754497_754701_+	excisionase	A0A1S5SF07	Streptococcus_phage	4.0e-31	100.0
WP_001291561.1\|754782_756000_+\|transposase	transposase	A0A1S5SEW7	Streptococcus_phage	3.7e-233	100.0
WP_002378125.1\|756250_758143_+	TPM domain-containing protein	NA	NA	NA	NA
WP_002355866.1\|758571_758880_+	50S ribosomal protein L21	NA	NA	NA	NA
WP_002355867.1\|758912_759257_+\|protease	ribosomal-processing cysteine protease Prp	NA	NA	NA	NA
WP_002355868.1\|759269_759557_+	50S ribosomal protein L27	NA	NA	NA	NA
759529:759556	attL	NA	NA	NA	NA
WP_113821352.1\|759644_760799_-\|integrase	site-specific integrase	Q9AZK8	Lactococcus_phage	2.8e-65	36.1
WP_113821353.1\|760867_761437_-	DUF3221 domain-containing protein	NA	NA	NA	NA
WP_153246902.1\|761502_761931_-	ImmA/IrrE family metallo-endopeptidase	A0A0S2MV59	Bacillus_phage	3.8e-15	36.0
WP_016619057.1\|761951_762377_-	helix-turn-helix transcriptional regulator	A0A0M4QX29	Bacillus_phage	3.0e-36	59.0
WP_016619056.1\|762661_762847_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_113821355.1\|762876_763161_+	hypothetical protein	NA	NA	NA	NA
WP_113821356.1\|763174_763900_+	phage regulatory protein	A0A0P0IDD0	Lactobacillus_phage	1.4e-30	54.0
WP_002357001.1\|763925_764114_-	YegP family protein	NA	NA	NA	NA
WP_113821357.1\|764168_764378_+	hypothetical protein	D2IZ57	Enterococcus_phage	8.0e-19	75.8
WP_113821358.1\|764414_764753_+	hypothetical protein	NA	NA	NA	NA
WP_113821359.1\|764749_764977_+	hypothetical protein	D2IZX4	Enterococcus_phage	2.1e-33	94.7
WP_010712119.1\|764976_765090_+	hypothetical protein	D2IYT7	Enterococcus_phage	3.4e-08	93.5
WP_113821360.1\|765073_765553_+	siphovirus Gp157 family protein	A6M981	Geobacillus_virus	2.6e-33	50.3
WP_153246903.1\|765565_766549_+	hypothetical protein	E5DV80	Deep-sea_thermophilic_phage	2.9e-74	60.6
WP_113821362.1\|766600_767599_+	DUF4373 domain-containing protein	D2IZR2	Enterococcus_phage	3.9e-79	56.2
WP_113821363.1\|767602_767902_+	hypothetical protein	D2IZY1	Enterococcus_phage	3.0e-43	90.9
WP_113821364.1\|767919_768345_+	RusA family crossover junction endodeoxyribonuclease	D2IYU2	Enterococcus_phage	1.8e-65	88.6
WP_113821365.1\|768624_768885_+	hypothetical protein	NA	NA	NA	NA
WP_113821366.1\|769252_769669_+	autolysin	D2IZL7	Enterococcus_phage	1.0e-65	95.7
WP_105194856.1\|769761_770304_+	Bsp6I family restriction endonuclease	NA	NA	NA	NA
WP_105194857.1\|770410_771361_+	DNA cytosine methyltransferase	V5URQ5	Oenococcus_phage	2.1e-106	62.5
WP_113821367.1\|772306_772666_+	hypothetical protein	NA	NA	NA	NA
WP_113821368.1\|772724_773582_+\|terminase	small subunit of terminase	D2J000	Enterococcus_phage	1.5e-87	72.6
WP_113821369.1\|773559_774852_+\|terminase	PBSX family phage terminase large subunit	V5UQR5	Oenococcus_phage	1.2e-173	68.9
WP_104837029.1\|774851_776336_+\|portal	phage portal protein	A0A097QPZ5	Enterococcus_phage	3.8e-139	99.6
WP_113821370.1\|776328_777255_+\|head	phage head morphogenesis protein	A0A097QPZ9	Enterococcus_phage	1.8e-131	98.4
WP_002378456.1\|777359_778013_+	hypothetical protein	NA	NA	NA	NA
WP_002409777.1\|778026_778923_+	hypothetical protein	U3PDP8	Lactobacillus_phage	7.3e-69	49.5
WP_002363369.1\|778993_779326_+	hypothetical protein	A0A1W6JNH7	Staphylococcus_phage	2.7e-08	38.5
WP_002364301.1\|779322_779598_+	hypothetical protein	NA	NA	NA	NA
WP_002363372.1\|779594_779933_+	hypothetical protein	A0A1L2K255	Streptococcus_phage	1.8e-12	38.7
WP_002363373.1\|779929_780322_+	DUF3168 domain-containing protein	NA	NA	NA	NA
WP_002364302.1\|780340_780946_+\|tail	phage major tail protein, TP901-1 family	NA	NA	NA	NA
WP_002409776.1\|780948_781257_+	hypothetical protein	L0P8M2	Lactobacillus_phage	1.0e-06	74.3
WP_002409775.1\|781319_781718_+	hypothetical protein	NA	NA	NA	NA
WP_002364305.1\|781786_782092_+	hypothetical protein	NA	NA	NA	NA
WP_113821371.1\|782078_786533_+\|tail	phage tail tape measure protein	M1PKM6	Streptococcus_phage	2.9e-89	49.0
WP_002363380.1\|786529_787252_+	hypothetical protein	C5IUK4	Streptococcus_phage	1.2e-42	39.2
WP_113821372.1\|787251_788697_+	peptidase M23	A0A1X9IGI5	Lactococcus_phage	5.3e-77	39.2
WP_002363384.1\|789459_789912_+	hypothetical protein	C0LZY6	Enterococcus_phage	3.3e-17	40.3
WP_002363385.1\|789930_790326_+	hypothetical protein	NA	NA	NA	NA
WP_002368228.1\|790327_790450_+	XkdX family protein	NA	NA	NA	NA
WP_002364623.1\|790460_790670_+	hypothetical protein	NA	NA	NA	NA
WP_113821374.1\|790722_791829_+	N-acetylmuramoyl-L-alanine amidase	A0A139ZVY1	Enterococcus_phage	1.4e-85	49.0
WP_113821377.1\|791993_792860_+	ParA family protein	A0A1X9IGI7	Lactococcus_phage	2.6e-31	35.9
794369:794396	attR	NA	NA	NA	NA

DBSCAN-SWA_3

1105214 : 1122980

Enterococcus_phage(42.86%)

holin,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002366550.1\|1105214_1107608_+	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	1.7e-19	24.1
WP_002360497.1\|1107632_1107983_+	30S ribosome-binding factor RbfA	NA	NA	NA	NA
WP_002393873.1\|1108065_1108296_+	hypothetical protein	NA	NA	NA	NA
WP_002357857.1\|1108355_1108829_-	toxin	A0A097BY56	Enterococcus_phage	1.1e-60	71.2
WP_002361687.1\|1108875_1109358_-	helix-turn-helix transcriptional regulator	R9QTP6	Staphylococcus_phage	1.5e-20	48.6
WP_023627964.1\|1109524_1109707_+	hypothetical protein	NA	NA	NA	NA
WP_023627965.1\|1109737_1110508_+	DnaD domain protein	A0A0K0MX39	Streptococcus_phage	2.5e-33	57.0
WP_002366554.1\|1110526_1111369_+	ATP-binding protein	A0A0P0I3L9	Lactobacillus_phage	1.3e-30	30.7
WP_023627966.1\|1111371_1111464_+	hypothetical protein	NA	NA	NA	NA
WP_153246913.1\|1111456_1111828_+	hypothetical protein	NA	NA	NA	NA
WP_002379371.1\|1111847_1112255_+	transcriptional regulator	NA	NA	NA	NA
WP_153246914.1\|1112500_1112893_+	hypothetical protein	NA	NA	NA	NA
WP_002380206.1\|1112905_1113418_+\|tail	phage major tail protein, TP901-1 family	W6LP72	Streptococcus_phage	8.8e-35	49.4
WP_002357848.1\|1113450_1113810_+	hypothetical protein	A0A0F6N4J9	Staphylococcus_phage	7.6e-09	32.2
WP_153246915.1\|1113827_1114196_+	hypothetical protein	A0A1P8BLR3	Lactococcus_phage	1.7e-08	33.3
WP_016627154.1\|1114185_1117119_+	hypothetical protein	A0A1U9WR55	Streptococcus_virus	1.1e-09	25.0
WP_002365553.1\|1117120_1118047_+\|tail	phage tail family protein	C9E2K5	Enterococcus_phage	9.0e-147	78.6
WP_002397217.1\|1118059_1119517_+	phage minor structural protein, region	C9E2K6	Enterococcus_phage	1.5e-175	47.7
WP_016627152.1\|1119549_1121319_+	hypothetical protein	A0A097BYA8	Enterococcus_phage	8.9e-143	72.0
WP_002357842.1\|1121342_1121738_+\|holin	phage holin family protein	F0PIJ6	Enterococcus_phage	2.8e-33	48.9
WP_016627151.1\|1121882_1122980_+	SH3 domain protein	A0A139ZVY1	Enterococcus_phage	1.2e-76	44.3

DBSCAN-SWA_4

1551049 : 1559693

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002379519.1\|1551049_1551622_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	4.1e-25	35.1
WP_016626993.1\|1551618_1552650_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D8KMR0	Synechococcus_phage	2.2e-56	45.2
WP_016626992.1\|1552651_1554091_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	2.1e-49	33.0
WP_002360137.1\|1554066_1556286_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	2.2e-146	39.9
WP_002360136.1\|1556282_1556957_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_002357271.1\|1556957_1557209_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_010822912.1\|1557222_1557936_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3ELR0	Synechococcus_phage	7.4e-48	42.5
WP_153246934.1\|1558087_1559212_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_016626990.1\|1559204_1559693_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	6.4e-19	42.0

DBSCAN-SWA_5

1709072 : 1765019

Enterococcus_phage(62.5%)

tRNA,head,tail,integrase,portal,terminase,holin

attL 1724605:1724623|attR 1765075:1765093

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010717649.1\|1709072_1710842_-\|tRNA	aspartate--tRNA ligase	A0A2K9L424	Tupanvirus	3.0e-13	30.3
WP_002366882.1\|1710859_1712161_-\|tRNA	histidine--tRNA ligase	A0A2I2L577	Orpheovirus	8.8e-23	26.8
WP_002362050.1\|1712157_1712406_-	hypothetical protein	NA	NA	NA	NA
WP_002357080.1\|1712518_1712965_-\|tRNA	D-tyrosyl-tRNA(Tyr) deacylase	NA	NA	NA	NA
WP_002366884.1\|1712988_1715202_-	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	A0A2I2L310	Orpheovirus	1.3e-10	38.0
WP_002357078.1\|1715416_1716169_-	16S rRNA (uracil(1498)-N(3))-methyltransferase	NA	NA	NA	NA
WP_002357075.1\|1716170_1717118_-	50S ribosomal protein L11 methyltransferase	NA	NA	NA	NA
WP_002388170.1\|1717133_1717619_-	DUF3013 family protein	NA	NA	NA	NA
WP_002383132.1\|1717575_1718265_-	DNA-3-methyladenine glycosylase	NA	NA	NA	NA
WP_002360030.1\|1718381_1719659_+	replication-associated recombination protein A	A0A127AWE7	Bacillus_phage	1.8e-105	49.9
WP_002380425.1\|1719986_1720265_+	hypothetical protein	NA	NA	NA	NA
WP_002357065.1\|1720578_1721052_+	universal stress protein	NA	NA	NA	NA
WP_002357064.1\|1721156_1722344_-	acetate kinase	NA	NA	NA	NA
WP_002357063.1\|1722368_1723376_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_002357061.1\|1723504_1723858_-	hypothetical protein	NA	NA	NA	NA
WP_002357060.1\|1723857_1724292_-	ComGF family competence protein	NA	NA	NA	NA
WP_123836446.1\|1724281_1724731_-	type II secretion system protein	NA	NA	NA	NA
1724605:1724623	attL	NA	NA	NA	NA
WP_123836470.1\|1724803_1725289_-	hypothetical protein	NA	NA	NA	NA
WP_002388442.1\|1725364_1725835_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_123836447.1\|1725956_1727258_-	LysM peptidoglycan-binding domain-containing protein	D2J077	Enterococcus_phage	3.2e-230	95.6
WP_002380792.1\|1727260_1727467_-\|holin	holin	A0A0S2MYF6	Enterococcus_phage	2.6e-30	100.0
WP_002397443.1\|1727463_1727685_-	hypothetical protein	A0A0S2MYL7	Enterococcus_phage	3.7e-30	98.6
WP_052864560.1\|1727712_1727868_-	XkdX family protein	A0A1W6JQ64	Staphylococcus_phage	3.6e-08	53.3
WP_123836448.1\|1727869_1728202_-	hypothetical protein	NA	NA	NA	NA
WP_153246937.1\|1728220_1728763_-	hypothetical protein	X2KQE1	Enterococcus_phage	1.6e-18	31.0
WP_002357046.1\|1728762_1729050_-	collagen-like protein	NA	NA	NA	NA
WP_104877178.1\|1729046_1729643_-	hypothetical protein	NA	NA	NA	NA
WP_104877177.1\|1729635_1730517_-	DUF2479 domain-containing protein	NA	NA	NA	NA
WP_123836449.1\|1730535_1733328_-	CHAP domain-containing protein	Q9AZX5	Lactococcus_phage	1.8e-145	38.7
WP_002357042.1\|1733324_1734059_-	hypothetical protein	NA	NA	NA	NA
WP_123836450.1\|1734048_1736973_-	tape measure protein	D7RWD8	Brochothrix_phage	1.1e-78	47.0
WP_010820912.1\|1737193_1737544_-	hypothetical protein	A0A2H4JAA8	uncultured_Caudovirales_phage	5.0e-05	33.3
WP_010716866.1\|1737596_1738445_-\|tail	phi13 family phage major tail protein	A0A288TYF3	Enterococcus_phage	3.2e-05	42.5
WP_002357037.1\|1738445_1738820_-	hypothetical protein	NA	NA	NA	NA
WP_016633079.1\|1738822_1739221_-	HK97 gp10 family phage protein	NA	NA	NA	NA
WP_002407273.1\|1739213_1739582_-	hypothetical protein	NA	NA	NA	NA
WP_048954256.1\|1739578_1739923_-	hypothetical protein	NA	NA	NA	NA
WP_002387281.1\|1739936_1740119_-	hypothetical protein	NA	NA	NA	NA
WP_002357030.1\|1740147_1741035_-	hypothetical protein	NA	NA	NA	NA
WP_010820917.1\|1741048_1741672_-	DUF4355 domain-containing protein	NA	NA	NA	NA
WP_002380436.1\|1741890_1742211_-	hypothetical protein	NA	NA	NA	NA
WP_002380437.1\|1742267_1742498_-	hypothetical protein	NA	NA	NA	NA
WP_123836451.1\|1742498_1744400_-\|head	head protein	NA	NA	NA	NA
WP_010708015.1\|1744377_1745862_-\|portal	phage portal protein	A0A0A7AQF2	Bacillus_phage	2.5e-29	25.5
WP_002397463.1\|1745873_1747163_-\|terminase	PBSX family phage terminase large subunit	D2J001	Enterococcus_phage	1.1e-232	95.1
WP_123836452.1\|1747134_1747938_-\|terminase	small subunit of terminase	D2J000	Enterococcus_phage	2.4e-103	78.7
WP_104888267.1\|1747995_1748184_-	hypothetical protein	C9E2P9	Enterococcus_phage	2.0e-24	96.8
WP_002363360.1\|1748321_1748513_-	hypothetical protein	D2IZZ6	Enterococcus_phage	1.5e-24	95.2
WP_123836453.1\|1748550_1749885_-	chromosome partitioning protein ParB	D2IZZ5	Enterococcus_phage	1.5e-214	81.5
WP_002390186.1\|1749887_1750055_-	hypothetical protein	NA	NA	NA	NA
WP_123836454.1\|1750641_1750932_-	hypothetical protein	NA	NA	NA	NA
WP_002364337.1\|1750937_1751354_-	autolysin	D2IZL7	Enterococcus_phage	7.1e-67	97.8
WP_123836455.1\|1751815_1752379_-	DUF3850 domain-containing protein	C9E2N9	Enterococcus_phage	1.0e-44	52.7
WP_123836456.1\|1752390_1752597_-	hypothetical protein	NA	NA	NA	NA
WP_123836457.1\|1752727_1753078_-	hypothetical protein	D2IYU9	Enterococcus_phage	6.0e-35	98.6
WP_002396629.1\|1753227_1753983_-	N-6 DNA methylase	A0A2K9V411	Faecalibacterium_phage	9.6e-30	34.2
WP_002368217.1\|1754189_1754375_-	hypothetical protein	NA	NA	NA	NA
WP_033658923.1\|1754374_1754800_-	RusA family crossover junction endodeoxyribonuclease	D2IYU2	Enterococcus_phage	1.1e-67	91.5
WP_002396626.1\|1754799_1755753_-	hypothetical protein	C9E2N2	Enterococcus_phage	1.2e-96	66.8
WP_002396625.1\|1755756_1756437_-	hypothetical protein	C9E2N1	Enterococcus_phage	4.4e-98	75.2
WP_123836471.1\|1756433_1757372_-	DUF1351 domain-containing protein	A0A0S2MYB3	Enterococcus_phage	2.0e-93	66.1
WP_127341765.1\|1757356_1758034_-	ERF family protein	A0A0S2MYH3	Enterococcus_phage	2.5e-114	92.4
WP_002368203.1\|1758017_1758272_-	hypothetical protein	A0A0S2MYD6	Enterococcus_phage	2.9e-23	74.4
WP_099704310.1\|1758338_1758452_-	hypothetical protein	C9E2M6	Enterococcus_phage	1.1e-06	79.4
WP_010826439.1\|1758451_1758775_-	hypothetical protein	D2IYT5	Enterococcus_phage	7.2e-51	96.3
WP_002368200.1\|1758846_1759590_-	hypothetical protein	U4KJ90	Streptococcus_phage	3.7e-42	41.3
WP_002363338.1\|1759602_1760010_-	hypothetical protein	A0A097BY30	Enterococcus_phage	2.3e-17	39.4
WP_099704311.1\|1760053_1760278_-	hypothetical protein	D2IZW8	Enterococcus_phage	3.6e-25	100.0
WP_099704312.1\|1760288_1760474_-	hypothetical protein	D2IZW5	Enterococcus_phage	5.6e-24	98.3
WP_087548635.1\|1760484_1761198_-	phage regulatory protein	D2IYT0	Enterococcus_phage	1.2e-90	77.1
WP_010773395.1\|1761236_1761548_-	hypothetical protein	NA	NA	NA	NA
WP_002356998.1\|1761559_1761751_-	hypothetical protein	NA	NA	NA	NA
WP_002396615.1\|1762043_1762385_+	helix-turn-helix transcriptional regulator	Q8W5Y0	Listeria_phage	2.1e-16	39.6
WP_123836459.1\|1762389_1763040_+	ImmA/IrrE family metallo-endopeptidase	S4U0J6	uncultured_phage	3.5e-12	29.4
WP_010706502.1\|1763150_1763765_+	SHOCT domain-containing protein	O48432	Lactobacillus_phage	2.6e-09	33.6
WP_002396613.1\|1763870_1765019_+\|integrase	site-specific integrase	A0A0M5M609	Bacillus_phage	6.6e-38	28.8
1765075:1765093	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP042217

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP042216

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection