CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP045750	Listeria monocytogenes strain CFSAN008100 plasmid pCFSAN008100, complete sequence	0 crisprs	cas5,csa3	0	0	1	0
NZ_CP045749	Listeria monocytogenes strain CFSAN008100 chromosome, complete genome	2 crisprs	WYL,DinG,cas3,DEDDh,RT,casR,csa3	0	0	6	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

40154 : 48999

Streptococcus_phage(33.33%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003728521.1\|40154_40538_-	DUF3850 domain-containing protein	C9E2N9	Enterococcus_phage	2.2e-14	53.4
WP_003731676.1\|40550_41213_-	DUF2786 domain-containing protein	NA	NA	NA	NA
WP_003728462.1\|41212_41539_-	hypothetical protein	A0A2K9V3N4	Faecalibacterium_phage	3.2e-06	40.8
WP_003728463.1\|41669_41921_+	hypothetical protein	NA	NA	NA	NA
WP_003728464.1\|41981_42224_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_003728465.1\|42217_42559_+	type II toxin-antitoxin system PemK/MazF family toxin	NA	NA	NA	NA
WP_003728466.1\|42751_44887_-	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	1.6e-247	64.5
WP_003728467.1\|44886_45246_-	Cd(II)-sensing metalloregulatory transcriptional repressor CadC	E4ZFI8	Streptococcus_phage	3.1e-26	50.0
WP_003728468.1\|45525_46080_+	recombinase family protein	A0A0F7LA37	Escherichia_phage	7.0e-38	53.4
WP_003728469.1\|46083_48999_+\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	1.9e-174	36.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP045749

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP045749_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045749_1

2606794-2607051

Orphan

Consensus_repeat	Method
CATATTAGTAACGGAACTCGTATC	CRISPRCasFinder

3 spacers

The CRISPR arrays of NZ_CP045749_1

>merge|NZ_CP045749|1|2606794-2607051|CRISPRCasFinder
CATGTCAGTCATTGAACTGGTATCAAAGGTACTTAAATCTAGCTCTTCAAGACTAGTACAATTTTGAAACATTCTATTCATATTAGTAACGGAACTCGTATCCCAATTGCTTACATCCAAAATCTCCAGTGATCCACAACCCGAAAACATGGAATACATATTAGTAACGGAACTGGTATCAAAATGACTTAAATCTAACTCTTCAAGACCAGAGCAAAATTGAAACATGCCATATATATTAGTTATAGCACTCGTATC

>NZ_CP045749|1|1|2606794-2607051|CRISPRCasFinder
CATGTCAGTCATTGAACTGGTATC	AAAGGTACTTAAATCTAGCTCTTCAAGACTAGTACAATTTTGAAACATTCTATT
CATATTAGTAACGGAACTCGTATC	CCAATTGCTTACATCCAAAATCTCCAGTGATCCACAACCCGAAAACATGGAATA
CATATTAGTAACGGAACTGGTATC	AAAATGACTTAAATCTAACTCTTCAAGACCAGAGCAAAATTGAAACATGCCATA
TATATTAGTTATAGCACTCGTATC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045749.1\|WP_003728092.1\|2614502_2616053_-\|hydantoinase/oxoprolinase-family-protein	unknown	unknown	gnl\|CDD\|223223
NZ_CP045749.1\|WP_023550583.1\|2604921_2605407_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045749.1\|WP_003725189.1\|2617146_2618430_-\|cytosine-permease	unknown	unknown	gnl\|CDD\|271377
NZ_CP045749.1\|WP_046811179.1\|2610063_2612067_-\|BspA-family-leucine-rich-repeat-surface-protein	unknown	unknown	gnl\|CDD\|308794
NZ_CP045749.1\|WP_003725208.1\|2599509_2600613_-\|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN	unknown	unknown	gnl\|CDD\|237717
NZ_CP045749.1\|WP_023550311.1\|2612330_2613869_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|368260
NZ_CP045749.1\|WP_003740428.1\|2618564_2620160_-\|PucR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225306
NZ_CP045749.1\|WP_023550585.1\|2605426_2605900_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045749.1\|WP_003725775.1\|2604246_2604513_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045749.1\|WP_009930283.1\|2604588_2604894_-\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|273478
NZ_CP045749.1\|WP_003728986.1\|2600763_2602464_-\|oleate-hydratase	unknown	unknown	gnl\|CDD\|227060
NZ_CP045749.1\|WP_003721271.1\|2598417_2598783_-\|heme-oxygenase-IsdG	unknown	unknown	gnl\|CDD\|183970
NZ_CP045749.1\|WP_003725186.1\|2622412_2624572_+\|transglutaminase	unknown	unknown	gnl\|CDD\|376628
NZ_CP045749.1\|WP_003721242.1\|2620315_2621263_+\|MoxR-family-ATPase	unknown	unknown	gnl\|CDD\|223786
NZ_CP045749.1\|WP_003728093.1\|2616045_2617146_-\|DUF917-domain-containing-protein	unknown	unknown	gnl\|CDD\|226065
NZ_CP045749.1\|WP_003731249.1\|2596380_2598144_-\|RNA-directed-DNA-polymerase	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|238824
NZ_CP045749.1\|WP_026747115.1\|2607858_2609928_-\|BspA-family-leucine-rich-repeat-surface-protein	unknown	unknown	gnl\|CDD\|308794
NZ_CP045749.1\|WP_003725209.1\|2598940_2599420_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|226231
NZ_CP045749.1\|WP_003733207.1\|2602573_2603134_-\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379534
NZ_CP045749.1\|WP_009929138.1\|2621267_2622416_+\|DUF58-domain-containing-protein	unknown	unknown	gnl\|CDD\|224635

Protein	Function_ID	Function_description	E-value
NZ_CP045749.1\|WP_003731249.1\|2596380_2598144_-\|RNA-directed-DNA-polymerase	gnl\|CDD\|238824	cd01646, RT_Bac_retron_I, RT_Bac_retron_I: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA branches out from a small ssRNA molecule via a 2'-5'phosphodiester linkage. Bacterial retron RTs produce cDNA corresponding to only a small portion of the retron genome.	1.43128e-28
NZ_CP045749.1\|WP_003725189.1\|2617146_2618430_-\|cytosine-permease	gnl\|CDD\|271377	cd11484, SLC-NCS1sbd_CobB-like, nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain. This NCS1 subfamily includes Escherichia coli CodB (cytosine permease), and the Saccharomyces cerevisiae transporters: Fcy21p (Purine-cytosine permease), and vitamin B6 transporter Tpn1. NCS1s are essential components of salvage pathways for nucleobases and related metabolites; their known substrates include allantoin, uracil, thiamine, and nicotinamide riboside. NCS1s belong to a superfamily which also contains the solute carrier 5 family sodium/glucose transporters (SLC5s), and solute carrier 6 family neurotransmitter transporters (SLC6s).	2.40318e-96
NZ_CP045749.1\|WP_046811179.1\|2610063_2612067_-\|BspA-family-leucine-rich-repeat-surface-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	1.33017e-30
NZ_CP045749.1\|WP_003725208.1\|2599509_2600613_-\|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN	gnl\|CDD\|237717	PRK14455, PRK14455, ribosomal RNA large subunit methyltransferase N; Provisional.	0
NZ_CP045749.1\|WP_023550311.1\|2612330_2613869_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|368260	pfam05043, Mga, Mga helix-turn-helix domain. M regulator protein trans-acting positive regulator (Mga) is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. This domain is found in the centre of the Mga proteins. This family also contains a number of bacterial RofA transcriptional regulators that seem to be largely restricted to streptococci. These proteins have been shown to regulate the expression of important bacterial adhesins. This is presumably a DNA-binding domain.	1.01429e-19
NZ_CP045749.1\|WP_003740428.1\|2618564_2620160_-\|PucR-family-transcriptional-regulator	gnl\|CDD\|225306	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism].	2.42853e-59
NZ_CP045749.1\|WP_009930283.1\|2604588_2604894_-\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|273478	TIGR01167, Zinc_metalloprotease_ZmpB, LPXTG-motif cell wall anchor domain. This model describes the LPXTG motif-containing region found at the C-terminus of many surface proteins of Streptococcus and Streptomyces species. Cleavage between the Thr and Gly by sortase or a related enzyme leads to covalent anchoring at the new C-terminal Thr to the cell wall. Hits that do not lie at the C-terminus or are not found in Gram-positive bacteria are probably false-positive. A common feature of this proteins containing this domain appears to be a high proportion of charged and zwitterionic residues immediatedly upstream of the LPXTG motif. This model differs from other descriptions of the LPXTG region by including a portion of that upstream charged region. [Cell envelope, Other].	1.67487e-05
NZ_CP045749.1\|WP_003728986.1\|2600763_2602464_-\|oleate-hydratase	gnl\|CDD\|227060	COG4716, COG4716, Myosin-crossreactive antigen [Function unknown].	0
NZ_CP045749.1\|WP_003721271.1\|2598417_2598783_-\|heme-oxygenase-IsdG	gnl\|CDD\|183970	PRK13316, PRK13316, heme oxygenase IsdG.	3.55164e-70
NZ_CP045749.1\|WP_003725186.1\|2622412_2624572_+\|transglutaminase	gnl\|CDD\|376628	pfam01841, Transglut_core, Transglutaminase-like superfamily. This family includes animal transglutaminases and other bacterial proteins of unknown function. Sequence conservation in this superfamily primarily involves three motifs that centre around conserved cysteine, histidine, and aspartate residues that form the catalytic triad in the structurally characterized transglutaminase, the human blood clotting factor XIIIa'. On the basis of the experimentally demonstrated activity of the Methanobacterium phage pseudomurein endoisopeptidase, it is proposed that many, if not all, microbial homologs of the transglutaminases are proteases and that the eukaryotic transglutaminases have evolved from an ancestral protease.	4.40206e-28
NZ_CP045749.1\|WP_003721242.1\|2620315_2621263_+\|MoxR-family-ATPase	gnl\|CDD\|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	7.47241e-102
NZ_CP045749.1\|WP_003728093.1\|2616045_2617146_-\|DUF917-domain-containing-protein	gnl\|CDD\|226065	COG3535, COG3535, Uncharacterized conserved protein [Function unknown].	0
NZ_CP045749.1\|WP_003725209.1\|2598940_2599420_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|226231	COG3708, COG3708, Uncharacterized protein conserved in bacteria [Function unknown].	1.03205e-42
NZ_CP045749.1\|WP_026747115.1\|2607858_2609928_-\|BspA-family-leucine-rich-repeat-surface-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	8.72154e-31
NZ_CP045749.1\|WP_003728092.1\|2614502_2616053_-\|hydantoinase/oxoprolinase-family-protein	gnl\|CDD\|223223	COG0145, HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	1.15698e-106
NZ_CP045749.1\|WP_003733207.1\|2602573_2603134_-\|TetR-family-transcriptional-regulator	gnl\|CDD\|379534	pfam14278, TetR_C_8, Transcriptional regulator C-terminal region. This domain is a tetracycline repressor, domain 2, or C-terminus.	2.23521e-25
NZ_CP045749.1\|WP_009929138.1\|2621267_2622416_+\|DUF58-domain-containing-protein	gnl\|CDD\|224635	COG1721, COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only].	1.37557e-52

>NZ_CP045749.1|WP_023550585.1|2605426_2605900_-|hypothetical-protein
MKKKRVVIISLLLLLVSVIGISSYFLFKDKINLLDVDPSAVEWNGKKQKDTSGEENTIAIPGFEKVTLYANETTQAVNFHNPEINDCYFKISLIHPDGSVLWISDLIEPGKGMYSIELEKPLAVGEYENAVLKYECFSLNDQSPLNGSEINLKLVVV
>NZ_CP045749.1|WP_023550583.1|2604921_2605407_-|hypothetical-protein
MNKLVLSTLSVAAMGMVIFSGGTAYAADKEGNTVVEYSVEGDYTLVVPEKVNLSNDNATEMSVKTINRNLEPGKEVEVTLSSGLSADGEIELQRVGATSDVITSSFKSNNSVVPMANPIIGSFSGYAMEETEVSKIQIGNPQGDKKAGAYQTTLTFTAAFK
>NZ_CP045749.1|WP_009930283.1|2604588_2604894_-|LPXTG-cell-wall-anchor-domain-containing-protein
MKRKLVLAMVLISFCGMFLLSPERVQASQTVVEVFISEDDLDVSEENIQEIPKKELAASSDKDNKQHTLPKAGDTVTNYTLLGLVLILIWLIMQRKRKKKE
>NZ_CP045749.1|WP_003725775.1|2604246_2604513_-|hypothetical-protein
MARIEYEEKIQKSLLVLYFRGSTIQSICREYGIPRYEFHKWMKLHDADKLETKEVKTFLQIRELKQQKNKLEEEILFLNEAINLLESP
>NZ_CP045749.1|WP_003733207.1|2602573_2603134_-|TetR-family-transcriptional-regulator
MAESLITKKAIAGGLMELCQHKRFEKISIADITNICGLNRQTFYYHFTDKYDLLTWTYENDFFHCLADGITLGNWDKHVLKMLESIKENADFYKNTVSADASILSFCFSKLTNSLFMDLFEKIDTNGAVNEADRVFYAEFFSYGCSGVLIKWITRGFKEAPETIANQLFRLAKDTEFLANSMYREN
>NZ_CP045749.1|WP_003728986.1|2600763_2602464_-|oleate-hydratase
MKNKKRTLVALTGAAIGTGIAAKKISEQKAAEKERAVDEAIKARYYGDKQVYFVGGGIASLAGAVYLIRDANFDGKNIHIIEGMHILGGSNDGAGSVEHGFVCRGGRMLNEETYENFWDLFSSIPSLDMPNFSVTEEILNFDHLHPTHAQARLVDKDRNILDAHSMGFNNNDRMLMTKLLATPEEKLDNLTIRDWFDEHFFETNFWYMWQTTFAFQKWSSLFEFRRYMNRMMLEFSRIDTLEGVTRTPLNQYESLILPLKTFLDKHHVDFTINQTVEDIDFKDAPGITATALHLSDGSTIELGPDDDVIMTNACMTDSATLGDMNTPAPKPEEKPISGELWYKVAQKKPNLGNPEPFFGHEEETNWQSFTVTCHGDKLLKRIERFTGNIPGSGALMTFKDSNWLMSTVVAAQPHFKAQDANTTIFWGYGLYPDRVGDFVKKPMKECTGEEILYELMCHLNWQDDFEEIKADIINVIPCYMPYIDAQFEPRAMSDRPAVVPEGSTNFAMISQFVEIPKDMVFTEEYSVRAARIAVYTLLDIDKKICPVTPHNRDPKVLAKATQTMFR
>NZ_CP045749.1|WP_003725208.1|2599509_2600613_-|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN
MEKSSIYGLTWTKLTEWLEAHGQKKFRATQVWDWLYRKRVKTFEEMSNVPKETIELLTANFVMNTLEEQVVQESTDGTTKYLFKLSDGNLIETVMMKQEYGLSVCVTTQVGCNIGCTFCASGLLKKSRDLTAGEIVEQIMNVQHYLDGRNLEERVSHVVVMGIGEPFDNYDNVMDFLRVINHDKGLAIGARHITVSTSGLAPRIIDFANEDFQVNLAISLHAPNNELRTSIMRINKTYSIEKLMEAIHYYVNKTNRRITFEYIMLKGVNDHKKEALELAALLGEHRHLAYVNLIPYNPVDEHIDYERSTKEDVLAFYDTLKKNGINCVIRREHGTDIDAACGQLRSKQIKRVGVRERMKQKQAAAEE
>NZ_CP045749.1|WP_003725209.1|2598940_2599420_-|AraC-family-transcriptional-regulator
MEVEIVERNAFTAVGKKRTFSVENDAQKEKISQFWQEANTNGDAERINELAEFATIDGILGVCKMNGDKMDYYIAIESELTPPADMEKLIIPASKWAIFKSVGPLPSAIQKVWEYIYGEWFQTSNYAHGNAPELEVYTEGDTTAADYYSEVWIPVVEKE
>NZ_CP045749.1|WP_003721271.1|2598417_2598783_-|heme-oxygenase-IsdG
MIIVTNTIKVEKGAAEHVIRQFTGANGDGHPTKDIAEVEGFLGFELWHSKPEDKDYEEVVVTSKWESEEAQRNWVKSDSFKKAHGRTKDTREQREDRKGIVGNAIARFEVVHVQNPVIVEK
>NZ_CP045749.1|WP_003731249.1|2596380_2598144_-|RNA-directed-DNA-polymerase
MRKKVDVLSMDNEKAREFFMKPSSYFSQNLPKYFNLGYLLESAESKLGKKQLKKEMYFENKVYSNFPNVNFLIQTNKTISTYRPITLLHPYIYVDYVNFLTEIKIWEELKERFQNLQEEVKEKIICSSLPFDIETSKEDDSKKEMALNFWKSIEQETIKYSLGYNYLLKLDISNFYGSIYTHTLCWAFHGENYSKEAKNSKNLQNLTGDKCDRKFQWMNYGETVGIPQGNVISDLMSELLLAYIDSELVKKIDDEIDYKIIRYRDDYRIFTKRLEDSTLVKRELVVLLQRFKLNLGESKTSQTTDIISGSLKEDKMYWIEHDPVTKLTSDKFYRSPKILMKKSLEEHKNKKYKTRVFNEFFKKHFHNRTYQATLQKHLLIIKVFSDLYPNSGQLIAALHEFEGRLLDLNYKDFRNIGTEVEVLIAILVDIIKKNPKITEIGVKLLSTLLKKINFEEFEMKYLESNNSNEVQSDFEVKLAYINSVNHKLSNSNYNDYLEIWMQRLVVKNLKESTTLSDLYIEQSKNELVKFCNSIIRGKEMIQIFNEDWLKDEHKIELSKFINLNEIDKLTDIISDDEIYLAEYNQMT
>NZ_CP045749.1|WP_026747115.1|2607858_2609928_-|BspA-family-leucine-rich-repeat-surface-protein
MKKLSIRVILIVTIIFIACGSANVSIAQERDIINKLPEVELGSLYTSNLITEEVAQDKPAEVENLEQAPTTDDLVQNPDVLEQPIADSDDSDLTVVNSGDFWTIYRNTVNGEYSLHMFGNVPSSKPTAWNSYLNRIKHIEIEEATLTGNFSSYFRNNVFTVLESVRIERSNLSRVTSFALAFYGSGIEKVIIRDNNYPTAPSLLTTEGMFKNCSNLMEVDLSGLDTSAVTTMWDMFNSCRALEELDVSNFDTSSVTNMSYMFYDNRNLEVLDVSNLDTGSVTNMYAMFEDCTSLEELDVSNFDTSSVTDMYRVFNGCEKLKKLDVSNFDTSSATAMVQMFRNCSALEKLDVSNFNTSLVTDMRAMFAGCTSLEALDVSNFDTSSVTNMAAMFSDNEKLEKLDLSTFDTSSVTNMGTMFKNCTALKSLFLDNFTHAASSTDMFTGTTSLSYLFVSHNVSNFNGLENTNWYDEKNWVQFSNLSQLQTYHRKQSEPTGYRKGEFLSLTMDAMGGQFEDAEEQKVQSKISGEYWEEVIPVKEGHYFDGWYLDQNFTNKFDFSLPATVSATLYAKWVENYTVVIPASISLNEATELKVEGINRGSKTLSVGLNYEETTISESNKLTLSNTADTTVQCLAPLSWDGSETNPKNAILTLAPGSEITEGDAVMEIESPENIQAGTYTGNLVFSINYE
>NZ_CP045749.1|WP_046811179.1|2610063_2612067_-|BspA-family-leucine-rich-repeat-surface-protein
MKKFSMRVVLIISVLFIALGNANVSIAQERDTTNKLPEVEIGSLDTSDVIAEEVAQDKPAEVENLEEIPTTDDLMQNPNVLEKSVADSDDSDLTVVSSGAYWTLYYNSANGEYSLRMFGNVPSSKPSAWNSYLNSIKHIEIEEATLTGSFASYFRDTGFPVLESVRIEQCNLSGVTSFARAFEGDSESESPLEKVIIRDNYYQETPSLTNISRMFTLCRKLSELDVSGLNTSSVTKMDTIFSNANSLKELDVSHFDTSSVTDMSSMFAACNSLEELDVSNFDTSSVTNMKYMLSGLHLKKLDVSNFDTSSVNNMLHMFYVCNNLEELDLSNFDTSSVTNMFAMFAYCTSLKEIDVSNFDTSSVTTMSAMFFECSSLEALDLSNFDTSSVTTMASMFENSTALKSLYLDNFTDAASMTDMFKGTTSLTYLFVSHNLSTFNRLENTSWYDEKNWVQFSNLSQLQTYHRKQSEPTGYRKGAFLSLTMDAMGGEFEDAEEQKVQNKVSGEYWEEIVPVKEDYYFDGWYLDQNFTNKFDFSLPAAVSTTIYAKWVENYTVIIPASISLNEATELKVEGINRGSKALSVGLNRLATSVSESNELTLANTADTTVQCSAPLSWDGSENNPEKAILTLAPGSEITEGDAVMAIEAPENIQAGKYTGNLVFSINYE
>NZ_CP045749.1|WP_023550311.1|2612330_2613869_-|helix-turn-helix-domain-containing-protein
MREYLDSKSQKKVALLEKIFYAENHTSTQEELLNDLNITYPTLISTIKTINFDIERFGYKAFSIVHSAPNLSYTLKISDNCSIQLIINAYIRESPKFQILETLLLASFPNLQALAKKVHVSYSGIKKEIKELNEELRERNLSISTGNQVEITGDEFSLRIFYAFLFLVAYSGDRWPFSFVQYDEITDILESCPKEIYRANSIDKAMMIHYYVAMHLLRDRMNCQIDTTRQFKVALYKACTEESKKSESAFIKKVAKQLPNRNYKEMTYTTQIILSTIVAFGSYSSIEKMPSFFYMDEQLEEMGFMKLVDFASEQVNDNLSIPFSEKEMELLRYSFASINYRYFLLDNLINKFNNIVPGYTNLDRNIRKIHKVNHLEPLISQLVNLKEMDPLKPFEERLASDYLIILDKRIDFSIHTLPIKVTILSTISNETAVFDFMRYFSSYYNLEIINQVDPVVDLYISDFSVSPEVLTSLRINQPIIYVNTRWLESDYVKINDNLAKIARKKFIANKKN
>NZ_CP045749.1|WP_003728092.1|2614502_2616053_-|hydantoinase/oxoprolinase-family-protein
MYKIGIDVGGTNTDAVILDENQQLIHSVKMPTSEDIETGITESLHRVLSETGIDRSKVTHAMLGTTQCTNAIVERKKLAKVGVLRLGYPATASVLPYTAWPEDMVGFLSGKYKLTGGGYEYDGQVLSEINEAEIRETLASWKGEVESVAVVGVFSSLKNDQELAVQKIIEEELGADIPVSISSSVGSVGLIERENATILNAALFKVIAATSDGFEKALEQEGIAHAEIYLCQNDGTLMSLNYARQFPILTIACGPTNSIRGASYLAGLKDAMVLDVGGTTSDIGVLTDGFPRESSLAVDVGGVRTNFRMPDIISIGLGGGSIVREKDGDITIGPDSVGYRISEEALVFGGKTMTTTDIAVRLGRAEIGNPELVAHIPTDFAEKAYKKIAEMTEDAIDKMKTSSGSVSLVLVGGGSVIIPDEISGVAQIFRDKNGPVANAIGASISQISGQYEQIYIYSQIEREEALQDAEQKAREQATLAGAVTDSIEVVEVEEIPLAYHPGNATRLRVKVVGNLV
>NZ_CP045749.1|WP_003728093.1|2616045_2617146_-|DUF917-domain-containing-protein
MRYLDEQAIENIAIGAAFLGTGGGGDPYIGKMMALTAIKKHGPIKLLSPEEIADDDYFIPAAMMGAPSVLIEKFPKGDEFVRVFEKLGRYVGKEVKGTFPMEAGGVNSMIPIVVAAQLGLPMVDCDGMGRAFPELQMVTFHLDGISATPMAITDEKGNIGIMETIDNKWTERLARVTTVEMGASSLVSLYPCNGAQIKQSSIKNIVTLSEEIGKVIRETSMDEAEKLQKLLDVTHGYHLFEGKITDVVRETRAGFNFGRVKIDGLNKDTGSEVIVHFQNENLVAEKNGEPIAITPDLICMVDLETLMPVTTEALKYGKRVRVMALPADDAWRTDKGIETVGPRYFGYDVDFEPLEELVKKEERRHV
>NZ_CP045749.1|WP_003725189.1|2617146_2618430_-|cytosine-permease
MTEKKSVEQTQSWQSLAFVWTGAMICVPSLLVGGTLISGMPLWEAILIALLGYGVIVLFMIYQGMQSSDLGIPAVSVASQVFGEQGSKKIISILLAIACLGWFGIQANVCGAAFSQFLGIYGINLPVPVSSLIWGVIMLLSAIYGIRILSILNYIAVPVLLFVCIYGLVVSLNDGGLAIVENYKPAGSMSFMTGLAITIGSFALGAVIAGDYSQYTKSRKDVVKAAIVGILPSGVLMITVGAVLALTAGTADISVVFTNLGLPVLGIIGLILAAWTTNAVNAFSGGIAIINVFNISEKYHKVAVAVAGGLGTILAVIGILNHFVPIMSVLSAMVPPVAGVMIASYWIVQKGDKSKWAPVPGVNWLGVSSWLVGAVIAGIPVILTFFPELPQLPNQPLIGIILSLAVYLIGAKVLSGKTNNVENLEGK
>NZ_CP045749.1|WP_003740428.1|2618564_2620160_-|PucR-family-transcriptional-regulator
MSVKLADLMKLPSLKEAKVVSGKSGLSKLVSSISVLEYTEVALLEDDLFDNDEFYGSEIVVSAFVNIRDDVEAQCRTIERLHKVGEVALILYYVGIFVPKMDQKLIDFANELDFTIIVMPENEMSLRYSEVIYEVVEAIVKQEMTDTNFVTESLEQISSVRPPQRNIDTTLKILSDRTHTSLVLTDNSFQVINSITWPRTRHWDFERIIEASKQIGEHELVQLTLDERDFYTARKPIFQDGMQAMHLFMMKEKGVLTADVVMQITEVVQVFMNLWGRNYVEISTAELMKAILNDESVKMRRLGKILNVDVSSIKWMWLVKTEEIRDNEQVLAELKSFVASHFQVSLIDLFEDNIVVLLDNSVAQRDRTHTANEFAMMMKEHGIDLKITVCQGMEQTSDVQSAYSLVNEYKNAANAIYANKSIYSLQEIDFAAKCVEIVDRGELAIAEQMRPLKPLEDNDELIETLSVFLLEGESNYNQAAELLFLHKNTIKYRIQRINELLQYPATKIPESYNLYLAVAIRRILGGNNNNK
>NZ_CP045749.1|WP_003721242.1|2620315_2621263_+|MoxR-family-ATPase
MSIEPSIKIEEIINEVEKVIVGKRHVVKLSLTALLAGGHVLLEDVPGVGKTMMVRTLSKTIGVSFKRIQFTPDLLPADVTGVSIFNPETRDFEFRPGPVMGNIVLADEINRTAPRTQAALLEGMAENSVTVDGITRKLANPFFVMATQNPIEYEGTYALPEAQLDRFLLKINIGYPTVEEEMQLLTLKQYQDPLDQTQQVVTLSELLDLKNKAKQVFIDDVLKNYIIRLVDATRKHPSVALGISPRGSLAFMQAAQAFALIEGRDYVIPDDIQYLAPYIFTHRLILKSEAYYNEETAESIIASILKNTSVPVEKR
>NZ_CP045749.1|WP_009929138.1|2621267_2622416_+|DUF58-domain-containing-protein
MLKKRLLLAFRWIIMLIIYAGLWTYTLFQGDTASWFLTYFFSFILLLLFLSSIYPLKAWKVNRRFVKNTYHDGDLIDMQVSFTRKSRYPVGYLLFQQKIPASFGNVSARQQVVYPLFKKHFTVTLAGFVGVRGIHSFPPVDVETSDAFGLLERSRQLSSEKSLTIYPTYFPDVLEKISEASPENERNAAYWTLKKNSNLHSLREFSSGDRISLIDWKSSAKSDQLMTREFENSATSRLSVIFYGASHPNFELSLRAAYSFIRKISEDNGEIRVTLLGDQTSKFAPAKGTSRLQDISTAFAEIAPVDSLTLQESLDSNLHSGEKILLFTPCIDTMLMQKVTRLTDNKQLQIITFQSEHSKAMDAPAIFLEPASLLSRWEREAK
>NZ_CP045749.1|WP_003725186.1|2622412_2624572_+|transglutaminase
MKRYLTLVMLFILSVLLISEWIYPFAELTELSTANWIILFITLSLGSFFLRLKYYWTIPLHIVMIIFVSGIYYAKGGILAGNWFVSFFQITFNGFRDMVQFRSSDISMDFILIVFLIALWLLSYITTYSILRKQRVMSVLVLTVAYLAVINTFTDYNSNWAIVRTVLEGFLLLHLALASRIAAPNRISADSLKRNGLFYHIFVILLLAVFVFSSLMLPKKAPIFPDPVPTIKNALGINTTRTVGYSEDDTTLGGALKKDNATVFTARAEKGHYWRVESKTVYTGTGWANANSADVISFSSGDNFPIQLTEQTTGATNTAEISFASSNDYMPYPYGTQTVNGAVDSFSANLTIERVGPVDTIKNYTVQLKTPVYNIEKMQNADFSTLSNAFVSQYTQTPKDLPDRVTKLANKVTKDADSIYDKTKAIERYLSASGTFTYSTEDAKETPRGADYVDQFLFETQIGYCDNFSTSMVVMLRSLGIPARWAKGYTPGEGEKKENDAKTTYTITNNNAHSWPEVFFPGTGWVPFEPTATFSNPENFQEPTTETANKPETPNDSTSTPETPNTADKTPEQDNGSSSTGETPKKEEPKTETAASNFEIPSWVWWIPAGLVVTLLALAIIFRRRIRRYLLLRSLRNSPEFGKTYHRLMKLLASYGYVRESSETLRHFSTRVDAELTTTEFSRLTKMYEAQIYSNNLTEKVITAEETQLVQQVIARLTK

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Crispr_ID: NZ_CP045749_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045749_2

2608687-2609271

Orphan

Consensus_repeat	Method
CATATNAGTTACTGAACTNGTATCAAAATTACTTACATC	CRT

7 spacers

The CRISPR arrays of NZ_CP045749_2

>merge|NZ_CP045749|2|2608687-2609271|CRT
CATGTTAGTCACTGAACTGGTATCAAAGGTACTTAAATCAAGCTTCTCCAGTTTTTCATTATCAGAAAACATGGCAGCCATATTAGTTACTGAACTCGTATCAAAATTACTTACATCTAACGCTTCAAGACTAGTACAACCAGCAAACATGGCACGCATATCAGTTACTAAGCTCGTATTAAAATTACTTACATCCAACTTCTCAAGGGCGCTACAATTTCTAAACATTTGAACCATTGCAGTAGCGGAACTGGTATCGAAATTACTTACATCTAGTTTCTTCAGTTTTTCACAGCCATTAAACACTCTATACATATCAGTTACTGAACTCGTATCAAAATTACTTACATCCAGCTCTTCAAGACTAGTACAATCTTCAAACATGGCATACATATTAGTTACTGAACCGGTATCAAGGTTGCTTACATCCAGCACCTCAAGGTTTCTATTATCATAAAACATGTAAGACATATTAGTTACTGAACTCGTATCAAAATTACTTACATCCAGTTCCTCAAGTGCCCTACAGCTGTTAAACATATCCCACATAGTAGTTACCGCACTAGTATCAAGACCACTCAAATC

>NZ_CP045749|2|1|2608687-2609271|CRT
CATGTTAGTCACTGAACTGGTATCAAAGGTACTTAAATC	AAGCTTCTCCAGTTTTTCATTATCAGAAAACATGGCAGC
CATATTAGTTACTGAACTCGTATCAAAATTACTTACATC	TAACGCTTCAAGACTAGTACAACCAGCAAACATGGCACG
CATATCAGTTACTAAGCTCGTATTAAAATTACTTACATC	CAACTTCTCAAGGGCGCTACAATTTCTAAACATTTGAAC
CATTGCAGTAGCGGAACTGGTATCGAAATTACTTACATC	TAGTTTCTTCAGTTTTTCACAGCCATTAAACACTCTATA
CATATCAGTTACTGAACTCGTATCAAAATTACTTACATC	CAGCTCTTCAAGACTAGTACAATCTTCAAACATGGCATA
CATATTAGTTACTGAACCGGTATCAAGGTTGCTTACATC	CAGCACCTCAAGGTTTCTATTATCATAAAACATGTAAGA
CATATTAGTTACTGAACTCGTATCAAAATTACTTACATC	CAGTTCCTCAAGTGCCCTACAGCTGTTAAACATATCCCA
CATAGTAGTTACCGCACTAGTATCAAGACCACTCAAATC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045749.1\|WP_003728092.1\|2614502_2616053_-\|hydantoinase/oxoprolinase-family-protein	unknown	unknown	gnl\|CDD\|223223
NZ_CP045749.1\|WP_023550583.1\|2604921_2605407_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045749.1\|WP_003725189.1\|2617146_2618430_-\|cytosine-permease	unknown	unknown	gnl\|CDD\|271377
NZ_CP045749.1\|WP_046811179.1\|2610063_2612067_-\|BspA-family-leucine-rich-repeat-surface-protein	unknown	unknown	gnl\|CDD\|308794
NZ_CP045749.1\|WP_003725208.1\|2599509_2600613_-\|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN	unknown	unknown	gnl\|CDD\|237717
NZ_CP045749.1\|WP_003734632.1\|2624688_2625444_+\|DUF4866-domain-containing-protein	unknown	unknown	gnl\|CDD\|379782
NZ_CP045749.1\|WP_023550311.1\|2612330_2613869_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|368260
NZ_CP045749.1\|WP_003740428.1\|2618564_2620160_-\|PucR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225306
NZ_CP045749.1\|WP_023550585.1\|2605426_2605900_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045749.1\|WP_003725775.1\|2604246_2604513_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045749.1\|WP_003728986.1\|2600763_2602464_-\|oleate-hydratase	unknown	unknown	gnl\|CDD\|227060
NZ_CP045749.1\|WP_046811180.1\|2605965_2607723_-\|BspA-family-leucine-rich-repeat-surface-protein	unknown	unknown	gnl\|CDD\|308794
NZ_CP045749.1\|WP_003725186.1\|2622412_2624572_+\|transglutaminase	unknown	unknown	gnl\|CDD\|376628
NZ_CP045749.1\|WP_003721242.1\|2620315_2621263_+\|MoxR-family-ATPase	unknown	unknown	gnl\|CDD\|223786
NZ_CP045749.1\|WP_003728093.1\|2616045_2617146_-\|DUF917-domain-containing-protein	unknown	unknown	gnl\|CDD\|226065
NZ_CP045749.1\|WP_003725209.1\|2598940_2599420_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|226231
NZ_CP045749.1\|WP_009929138.1\|2621267_2622416_+\|DUF58-domain-containing-protein	unknown	unknown	gnl\|CDD\|224635
NZ_CP045749.1\|WP_009930283.1\|2604588_2604894_-\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|273478
NZ_CP045749.1\|WP_003733207.1\|2602573_2603134_-\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379534
NZ_CP045749.1\|WP_003721271.1\|2598417_2598783_-\|heme-oxygenase-IsdG	unknown	unknown	gnl\|CDD\|183970

Protein	Function_ID	Function_description	E-value
NZ_CP045749.1\|WP_003725189.1\|2617146_2618430_-\|cytosine-permease	gnl\|CDD\|271377	cd11484, SLC-NCS1sbd_CobB-like, nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain. This NCS1 subfamily includes Escherichia coli CodB (cytosine permease), and the Saccharomyces cerevisiae transporters: Fcy21p (Purine-cytosine permease), and vitamin B6 transporter Tpn1. NCS1s are essential components of salvage pathways for nucleobases and related metabolites; their known substrates include allantoin, uracil, thiamine, and nicotinamide riboside. NCS1s belong to a superfamily which also contains the solute carrier 5 family sodium/glucose transporters (SLC5s), and solute carrier 6 family neurotransmitter transporters (SLC6s).	2.40318e-96
NZ_CP045749.1\|WP_046811179.1\|2610063_2612067_-\|BspA-family-leucine-rich-repeat-surface-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	1.33017e-30
NZ_CP045749.1\|WP_003725208.1\|2599509_2600613_-\|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN	gnl\|CDD\|237717	PRK14455, PRK14455, ribosomal RNA large subunit methyltransferase N; Provisional.	0
NZ_CP045749.1\|WP_023550311.1\|2612330_2613869_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|368260	pfam05043, Mga, Mga helix-turn-helix domain. M regulator protein trans-acting positive regulator (Mga) is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. This domain is found in the centre of the Mga proteins. This family also contains a number of bacterial RofA transcriptional regulators that seem to be largely restricted to streptococci. These proteins have been shown to regulate the expression of important bacterial adhesins. This is presumably a DNA-binding domain.	1.01429e-19
NZ_CP045749.1\|WP_003740428.1\|2618564_2620160_-\|PucR-family-transcriptional-regulator	gnl\|CDD\|225306	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism].	2.42853e-59
NZ_CP045749.1\|WP_003734632.1\|2624688_2625444_+\|DUF4866-domain-containing-protein	gnl\|CDD\|379782	pfam16160, DUF4866, Domain of unknown function (DUF4866). This family consists of uncharacterized proteins around 250 residues in length and is mainly found in various human gut Firmicute species and abundant in human gut metagenomic datasets. The function of this family is unknown.	2.71521e-121
NZ_CP045749.1\|WP_009930283.1\|2604588_2604894_-\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|273478	TIGR01167, Zinc_metalloprotease_ZmpB, LPXTG-motif cell wall anchor domain. This model describes the LPXTG motif-containing region found at the C-terminus of many surface proteins of Streptococcus and Streptomyces species. Cleavage between the Thr and Gly by sortase or a related enzyme leads to covalent anchoring at the new C-terminal Thr to the cell wall. Hits that do not lie at the C-terminus or are not found in Gram-positive bacteria are probably false-positive. A common feature of this proteins containing this domain appears to be a high proportion of charged and zwitterionic residues immediatedly upstream of the LPXTG motif. This model differs from other descriptions of the LPXTG region by including a portion of that upstream charged region. [Cell envelope, Other].	1.67487e-05
NZ_CP045749.1\|WP_003728986.1\|2600763_2602464_-\|oleate-hydratase	gnl\|CDD\|227060	COG4716, COG4716, Myosin-crossreactive antigen [Function unknown].	0
NZ_CP045749.1\|WP_046811180.1\|2605965_2607723_-\|BspA-family-leucine-rich-repeat-surface-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	5.56848e-29
NZ_CP045749.1\|WP_003725186.1\|2622412_2624572_+\|transglutaminase	gnl\|CDD\|376628	pfam01841, Transglut_core, Transglutaminase-like superfamily. This family includes animal transglutaminases and other bacterial proteins of unknown function. Sequence conservation in this superfamily primarily involves three motifs that centre around conserved cysteine, histidine, and aspartate residues that form the catalytic triad in the structurally characterized transglutaminase, the human blood clotting factor XIIIa'. On the basis of the experimentally demonstrated activity of the Methanobacterium phage pseudomurein endoisopeptidase, it is proposed that many, if not all, microbial homologs of the transglutaminases are proteases and that the eukaryotic transglutaminases have evolved from an ancestral protease.	4.40206e-28
NZ_CP045749.1\|WP_003721242.1\|2620315_2621263_+\|MoxR-family-ATPase	gnl\|CDD\|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	7.47241e-102
NZ_CP045749.1\|WP_003728093.1\|2616045_2617146_-\|DUF917-domain-containing-protein	gnl\|CDD\|226065	COG3535, COG3535, Uncharacterized conserved protein [Function unknown].	0
NZ_CP045749.1\|WP_003725209.1\|2598940_2599420_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|226231	COG3708, COG3708, Uncharacterized protein conserved in bacteria [Function unknown].	1.03205e-42
NZ_CP045749.1\|WP_009929138.1\|2621267_2622416_+\|DUF58-domain-containing-protein	gnl\|CDD\|224635	COG1721, COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only].	1.37557e-52
NZ_CP045749.1\|WP_003728092.1\|2614502_2616053_-\|hydantoinase/oxoprolinase-family-protein	gnl\|CDD\|223223	COG0145, HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	1.15698e-106
NZ_CP045749.1\|WP_003733207.1\|2602573_2603134_-\|TetR-family-transcriptional-regulator	gnl\|CDD\|379534	pfam14278, TetR_C_8, Transcriptional regulator C-terminal region. This domain is a tetracycline repressor, domain 2, or C-terminus.	2.23521e-25
NZ_CP045749.1\|WP_003721271.1\|2598417_2598783_-\|heme-oxygenase-IsdG	gnl\|CDD\|183970	PRK13316, PRK13316, heme oxygenase IsdG.	3.55164e-70

>NZ_CP045749.1|WP_046811180.1|2605965_2607723_-|BspA-family-leucine-rich-repeat-surface-protein
MKKFSMRVVLIISVLFIALGSANVSTAQERDTTNKLPEVELGSLDTSNIIAEEVAQEKPAEVEQLEEIPTTDELMQNPDVLEQPVADSDDTDLTVVSSGDFWTIYRNTVNNEYSLCMFGNVPSSRPTAWNTYLNRIKHIEIEEATLTGSFASYFSGDYFTVLESVKIEQCNLSGVTSFEKAFYNSGIEKVIIRDNDYPTAPSLLTTQYMFQLCRKLSELDLSGLDTSAITNIYGMFQFCSGLEELDLSHFDTSSVTNMYSMFSGCGSLEILDVSNWDTSSVTNMNRMFQNCTSLEELDLSTFDTSSMTDMGMMFNGCTALKSLYLDNFTDAAIMTDMFTGTTSLTYLFVSHNLSTFNNLENTSWYDEKNWVQFSNLSQLQTYHRNQSEPTGYRKGAFLSLTMDAMGGEFEDAEEQKVQNKISGEYWEEVIPVKEGHYFDGWYLDQNFTNKFDFSLPAAVSTTIYAKWVENYTVVIPASISLNEATELKVEGINRGSKTLSVGLNYGETTISGNNKLTLSNTADATVQCLVPLSWDGSENNPENAILTLAPGSEITEGDAVMEIKSPENIQAGKYTGNVVFSIKYE
>NZ_CP045749.1|WP_023550585.1|2605426_2605900_-|hypothetical-protein
MKKKRVVIISLLLLLVSVIGISSYFLFKDKINLLDVDPSAVEWNGKKQKDTSGEENTIAIPGFEKVTLYANETTQAVNFHNPEINDCYFKISLIHPDGSVLWISDLIEPGKGMYSIELEKPLAVGEYENAVLKYECFSLNDQSPLNGSEINLKLVVV
>NZ_CP045749.1|WP_023550583.1|2604921_2605407_-|hypothetical-protein
MNKLVLSTLSVAAMGMVIFSGGTAYAADKEGNTVVEYSVEGDYTLVVPEKVNLSNDNATEMSVKTINRNLEPGKEVEVTLSSGLSADGEIELQRVGATSDVITSSFKSNNSVVPMANPIIGSFSGYAMEETEVSKIQIGNPQGDKKAGAYQTTLTFTAAFK
>NZ_CP045749.1|WP_009930283.1|2604588_2604894_-|LPXTG-cell-wall-anchor-domain-containing-protein
MKRKLVLAMVLISFCGMFLLSPERVQASQTVVEVFISEDDLDVSEENIQEIPKKELAASSDKDNKQHTLPKAGDTVTNYTLLGLVLILIWLIMQRKRKKKE
>NZ_CP045749.1|WP_003725775.1|2604246_2604513_-|hypothetical-protein
MARIEYEEKIQKSLLVLYFRGSTIQSICREYGIPRYEFHKWMKLHDADKLETKEVKTFLQIRELKQQKNKLEEEILFLNEAINLLESP
>NZ_CP045749.1|WP_003733207.1|2602573_2603134_-|TetR-family-transcriptional-regulator
MAESLITKKAIAGGLMELCQHKRFEKISIADITNICGLNRQTFYYHFTDKYDLLTWTYENDFFHCLADGITLGNWDKHVLKMLESIKENADFYKNTVSADASILSFCFSKLTNSLFMDLFEKIDTNGAVNEADRVFYAEFFSYGCSGVLIKWITRGFKEAPETIANQLFRLAKDTEFLANSMYREN
>NZ_CP045749.1|WP_003728986.1|2600763_2602464_-|oleate-hydratase
MKNKKRTLVALTGAAIGTGIAAKKISEQKAAEKERAVDEAIKARYYGDKQVYFVGGGIASLAGAVYLIRDANFDGKNIHIIEGMHILGGSNDGAGSVEHGFVCRGGRMLNEETYENFWDLFSSIPSLDMPNFSVTEEILNFDHLHPTHAQARLVDKDRNILDAHSMGFNNNDRMLMTKLLATPEEKLDNLTIRDWFDEHFFETNFWYMWQTTFAFQKWSSLFEFRRYMNRMMLEFSRIDTLEGVTRTPLNQYESLILPLKTFLDKHHVDFTINQTVEDIDFKDAPGITATALHLSDGSTIELGPDDDVIMTNACMTDSATLGDMNTPAPKPEEKPISGELWYKVAQKKPNLGNPEPFFGHEEETNWQSFTVTCHGDKLLKRIERFTGNIPGSGALMTFKDSNWLMSTVVAAQPHFKAQDANTTIFWGYGLYPDRVGDFVKKPMKECTGEEILYELMCHLNWQDDFEEIKADIINVIPCYMPYIDAQFEPRAMSDRPAVVPEGSTNFAMISQFVEIPKDMVFTEEYSVRAARIAVYTLLDIDKKICPVTPHNRDPKVLAKATQTMFR
>NZ_CP045749.1|WP_003725208.1|2599509_2600613_-|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN
MEKSSIYGLTWTKLTEWLEAHGQKKFRATQVWDWLYRKRVKTFEEMSNVPKETIELLTANFVMNTLEEQVVQESTDGTTKYLFKLSDGNLIETVMMKQEYGLSVCVTTQVGCNIGCTFCASGLLKKSRDLTAGEIVEQIMNVQHYLDGRNLEERVSHVVVMGIGEPFDNYDNVMDFLRVINHDKGLAIGARHITVSTSGLAPRIIDFANEDFQVNLAISLHAPNNELRTSIMRINKTYSIEKLMEAIHYYVNKTNRRITFEYIMLKGVNDHKKEALELAALLGEHRHLAYVNLIPYNPVDEHIDYERSTKEDVLAFYDTLKKNGINCVIRREHGTDIDAACGQLRSKQIKRVGVRERMKQKQAAAEE
>NZ_CP045749.1|WP_003725209.1|2598940_2599420_-|AraC-family-transcriptional-regulator
MEVEIVERNAFTAVGKKRTFSVENDAQKEKISQFWQEANTNGDAERINELAEFATIDGILGVCKMNGDKMDYYIAIESELTPPADMEKLIIPASKWAIFKSVGPLPSAIQKVWEYIYGEWFQTSNYAHGNAPELEVYTEGDTTAADYYSEVWIPVVEKE
>NZ_CP045749.1|WP_003721271.1|2598417_2598783_-|heme-oxygenase-IsdG
MIIVTNTIKVEKGAAEHVIRQFTGANGDGHPTKDIAEVEGFLGFELWHSKPEDKDYEEVVVTSKWESEEAQRNWVKSDSFKKAHGRTKDTREQREDRKGIVGNAIARFEVVHVQNPVIVEK
>NZ_CP045749.1|WP_046811179.1|2610063_2612067_-|BspA-family-leucine-rich-repeat-surface-protein
MKKFSMRVVLIISVLFIALGNANVSIAQERDTTNKLPEVEIGSLDTSDVIAEEVAQDKPAEVENLEEIPTTDDLMQNPNVLEKSVADSDDSDLTVVSSGAYWTLYYNSANGEYSLRMFGNVPSSKPSAWNSYLNSIKHIEIEEATLTGSFASYFRDTGFPVLESVRIEQCNLSGVTSFARAFEGDSESESPLEKVIIRDNYYQETPSLTNISRMFTLCRKLSELDVSGLNTSSVTKMDTIFSNANSLKELDVSHFDTSSVTDMSSMFAACNSLEELDVSNFDTSSVTNMKYMLSGLHLKKLDVSNFDTSSVNNMLHMFYVCNNLEELDLSNFDTSSVTNMFAMFAYCTSLKEIDVSNFDTSSVTTMSAMFFECSSLEALDLSNFDTSSVTTMASMFENSTALKSLYLDNFTDAASMTDMFKGTTSLTYLFVSHNLSTFNRLENTSWYDEKNWVQFSNLSQLQTYHRKQSEPTGYRKGAFLSLTMDAMGGEFEDAEEQKVQNKVSGEYWEEIVPVKEDYYFDGWYLDQNFTNKFDFSLPAAVSTTIYAKWVENYTVIIPASISLNEATELKVEGINRGSKALSVGLNRLATSVSESNELTLANTADTTVQCSAPLSWDGSENNPEKAILTLAPGSEITEGDAVMAIEAPENIQAGKYTGNLVFSINYE
>NZ_CP045749.1|WP_023550311.1|2612330_2613869_-|helix-turn-helix-domain-containing-protein
MREYLDSKSQKKVALLEKIFYAENHTSTQEELLNDLNITYPTLISTIKTINFDIERFGYKAFSIVHSAPNLSYTLKISDNCSIQLIINAYIRESPKFQILETLLLASFPNLQALAKKVHVSYSGIKKEIKELNEELRERNLSISTGNQVEITGDEFSLRIFYAFLFLVAYSGDRWPFSFVQYDEITDILESCPKEIYRANSIDKAMMIHYYVAMHLLRDRMNCQIDTTRQFKVALYKACTEESKKSESAFIKKVAKQLPNRNYKEMTYTTQIILSTIVAFGSYSSIEKMPSFFYMDEQLEEMGFMKLVDFASEQVNDNLSIPFSEKEMELLRYSFASINYRYFLLDNLINKFNNIVPGYTNLDRNIRKIHKVNHLEPLISQLVNLKEMDPLKPFEERLASDYLIILDKRIDFSIHTLPIKVTILSTISNETAVFDFMRYFSSYYNLEIINQVDPVVDLYISDFSVSPEVLTSLRINQPIIYVNTRWLESDYVKINDNLAKIARKKFIANKKN
>NZ_CP045749.1|WP_003728092.1|2614502_2616053_-|hydantoinase/oxoprolinase-family-protein
MYKIGIDVGGTNTDAVILDENQQLIHSVKMPTSEDIETGITESLHRVLSETGIDRSKVTHAMLGTTQCTNAIVERKKLAKVGVLRLGYPATASVLPYTAWPEDMVGFLSGKYKLTGGGYEYDGQVLSEINEAEIRETLASWKGEVESVAVVGVFSSLKNDQELAVQKIIEEELGADIPVSISSSVGSVGLIERENATILNAALFKVIAATSDGFEKALEQEGIAHAEIYLCQNDGTLMSLNYARQFPILTIACGPTNSIRGASYLAGLKDAMVLDVGGTTSDIGVLTDGFPRESSLAVDVGGVRTNFRMPDIISIGLGGGSIVREKDGDITIGPDSVGYRISEEALVFGGKTMTTTDIAVRLGRAEIGNPELVAHIPTDFAEKAYKKIAEMTEDAIDKMKTSSGSVSLVLVGGGSVIIPDEISGVAQIFRDKNGPVANAIGASISQISGQYEQIYIYSQIEREEALQDAEQKAREQATLAGAVTDSIEVVEVEEIPLAYHPGNATRLRVKVVGNLV
>NZ_CP045749.1|WP_003728093.1|2616045_2617146_-|DUF917-domain-containing-protein
MRYLDEQAIENIAIGAAFLGTGGGGDPYIGKMMALTAIKKHGPIKLLSPEEIADDDYFIPAAMMGAPSVLIEKFPKGDEFVRVFEKLGRYVGKEVKGTFPMEAGGVNSMIPIVVAAQLGLPMVDCDGMGRAFPELQMVTFHLDGISATPMAITDEKGNIGIMETIDNKWTERLARVTTVEMGASSLVSLYPCNGAQIKQSSIKNIVTLSEEIGKVIRETSMDEAEKLQKLLDVTHGYHLFEGKITDVVRETRAGFNFGRVKIDGLNKDTGSEVIVHFQNENLVAEKNGEPIAITPDLICMVDLETLMPVTTEALKYGKRVRVMALPADDAWRTDKGIETVGPRYFGYDVDFEPLEELVKKEERRHV
>NZ_CP045749.1|WP_003725189.1|2617146_2618430_-|cytosine-permease
MTEKKSVEQTQSWQSLAFVWTGAMICVPSLLVGGTLISGMPLWEAILIALLGYGVIVLFMIYQGMQSSDLGIPAVSVASQVFGEQGSKKIISILLAIACLGWFGIQANVCGAAFSQFLGIYGINLPVPVSSLIWGVIMLLSAIYGIRILSILNYIAVPVLLFVCIYGLVVSLNDGGLAIVENYKPAGSMSFMTGLAITIGSFALGAVIAGDYSQYTKSRKDVVKAAIVGILPSGVLMITVGAVLALTAGTADISVVFTNLGLPVLGIIGLILAAWTTNAVNAFSGGIAIINVFNISEKYHKVAVAVAGGLGTILAVIGILNHFVPIMSVLSAMVPPVAGVMIASYWIVQKGDKSKWAPVPGVNWLGVSSWLVGAVIAGIPVILTFFPELPQLPNQPLIGIILSLAVYLIGAKVLSGKTNNVENLEGK
>NZ_CP045749.1|WP_003740428.1|2618564_2620160_-|PucR-family-transcriptional-regulator
MSVKLADLMKLPSLKEAKVVSGKSGLSKLVSSISVLEYTEVALLEDDLFDNDEFYGSEIVVSAFVNIRDDVEAQCRTIERLHKVGEVALILYYVGIFVPKMDQKLIDFANELDFTIIVMPENEMSLRYSEVIYEVVEAIVKQEMTDTNFVTESLEQISSVRPPQRNIDTTLKILSDRTHTSLVLTDNSFQVINSITWPRTRHWDFERIIEASKQIGEHELVQLTLDERDFYTARKPIFQDGMQAMHLFMMKEKGVLTADVVMQITEVVQVFMNLWGRNYVEISTAELMKAILNDESVKMRRLGKILNVDVSSIKWMWLVKTEEIRDNEQVLAELKSFVASHFQVSLIDLFEDNIVVLLDNSVAQRDRTHTANEFAMMMKEHGIDLKITVCQGMEQTSDVQSAYSLVNEYKNAANAIYANKSIYSLQEIDFAAKCVEIVDRGELAIAEQMRPLKPLEDNDELIETLSVFLLEGESNYNQAAELLFLHKNTIKYRIQRINELLQYPATKIPESYNLYLAVAIRRILGGNNNNK
>NZ_CP045749.1|WP_003721242.1|2620315_2621263_+|MoxR-family-ATPase
MSIEPSIKIEEIINEVEKVIVGKRHVVKLSLTALLAGGHVLLEDVPGVGKTMMVRTLSKTIGVSFKRIQFTPDLLPADVTGVSIFNPETRDFEFRPGPVMGNIVLADEINRTAPRTQAALLEGMAENSVTVDGITRKLANPFFVMATQNPIEYEGTYALPEAQLDRFLLKINIGYPTVEEEMQLLTLKQYQDPLDQTQQVVTLSELLDLKNKAKQVFIDDVLKNYIIRLVDATRKHPSVALGISPRGSLAFMQAAQAFALIEGRDYVIPDDIQYLAPYIFTHRLILKSEAYYNEETAESIIASILKNTSVPVEKR
>NZ_CP045749.1|WP_009929138.1|2621267_2622416_+|DUF58-domain-containing-protein
MLKKRLLLAFRWIIMLIIYAGLWTYTLFQGDTASWFLTYFFSFILLLLFLSSIYPLKAWKVNRRFVKNTYHDGDLIDMQVSFTRKSRYPVGYLLFQQKIPASFGNVSARQQVVYPLFKKHFTVTLAGFVGVRGIHSFPPVDVETSDAFGLLERSRQLSSEKSLTIYPTYFPDVLEKISEASPENERNAAYWTLKKNSNLHSLREFSSGDRISLIDWKSSAKSDQLMTREFENSATSRLSVIFYGASHPNFELSLRAAYSFIRKISEDNGEIRVTLLGDQTSKFAPAKGTSRLQDISTAFAEIAPVDSLTLQESLDSNLHSGEKILLFTPCIDTMLMQKVTRLTDNKQLQIITFQSEHSKAMDAPAIFLEPASLLSRWEREAK
>NZ_CP045749.1|WP_003725186.1|2622412_2624572_+|transglutaminase
MKRYLTLVMLFILSVLLISEWIYPFAELTELSTANWIILFITLSLGSFFLRLKYYWTIPLHIVMIIFVSGIYYAKGGILAGNWFVSFFQITFNGFRDMVQFRSSDISMDFILIVFLIALWLLSYITTYSILRKQRVMSVLVLTVAYLAVINTFTDYNSNWAIVRTVLEGFLLLHLALASRIAAPNRISADSLKRNGLFYHIFVILLLAVFVFSSLMLPKKAPIFPDPVPTIKNALGINTTRTVGYSEDDTTLGGALKKDNATVFTARAEKGHYWRVESKTVYTGTGWANANSADVISFSSGDNFPIQLTEQTTGATNTAEISFASSNDYMPYPYGTQTVNGAVDSFSANLTIERVGPVDTIKNYTVQLKTPVYNIEKMQNADFSTLSNAFVSQYTQTPKDLPDRVTKLANKVTKDADSIYDKTKAIERYLSASGTFTYSTEDAKETPRGADYVDQFLFETQIGYCDNFSTSMVVMLRSLGIPARWAKGYTPGEGEKKENDAKTTYTITNNNAHSWPEVFFPGTGWVPFEPTATFSNPENFQEPTTETANKPETPNDSTSTPETPNTADKTPEQDNGSSSTGETPKKEEPKTETAASNFEIPSWVWWIPAGLVVTLLALAIIFRRRIRRYLLLRSLRNSPEFGKTYHRLMKLLASYGYVRESSETLRHFSTRVDAELTTTEFSRLTKMYEAQIYSNNLTEKVITAEETQLVQQVIARLTK
>NZ_CP045749.1|WP_003734632.1|2624688_2625444_+|DUF4866-domain-containing-protein
MTTIFPKEQNVAPLFEQILANPTACRRFKDVFLDNLESYQETRGFEKDDTLFAKIILSAYRQSDVSALLLGVCGRTLFELLRQAFLIPKKLTVDNPFFLTDKEGNFIAKKDDISNREQEKFQEIYQSDLHHSETTIFLVDDDDIIHSYEPDFSISTKRINKKRGILVLYSLPDTLKLGMTESEVYAFIWKTFLHIQEIIPSSRIFYGQETSENADELGVFLPIHHFEKKMLQNIEQVNELVDALREQMVNK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

468831 : 476673

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003722610.1\|468831_469791_+	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	2.0e-88	53.7
WP_009918601.1\|469907_470891_+	UDP-glucose 4-epimerase GalE	A0A2K9L5H6	Tupanvirus	3.1e-52	38.7
WP_009918600.1\|470907_471969_+	galactose mutarotase	NA	NA	NA	NA
WP_003725409.1\|472010_473741_+	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	9.5e-174	53.1
WP_003722606.1\|473848_474724_+	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	1.9e-08	29.7
WP_003731212.1\|474725_475694_+	YvcK family protein	A1IMD5	Streptococcus_phage	1.8e-68	43.6
WP_003725407.1\|475701_476673_+	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	5.2e-52	39.4

DBSCAN-SWA_2

620995 : 663671

Listeria_phage(95.08%)

holin,tail,terminase,plate,portal,integrase

attL 626341:626356|attR 661623:661638

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003739618.1\|620995_621343_+	helix-turn-helix transcriptional regulator	A0A0A7RTK4	Clostridium_phage	9.9e-06	40.7
WP_031644186.1\|621397_621874_-	competence protein ComK	NA	NA	NA	NA
WP_009911646.1\|621864_623223_-	recombinase family protein	Q8LTD8	Listeria_phage	2.0e-251	97.1
WP_003770015.1\|623286_624162_-	hypothetical protein	A0A0B5D0D1	Listeria_phage	2.2e-150	94.5
WP_003770013.1\|624183_624906_-	hypothetical protein	A0A059T7P9	Listeria_phage	7.4e-88	84.6
WP_025370648.1\|624921_625140_-	zinc-ribbon domain-containing protein	A0A059T6E3	Listeria_phage	1.3e-32	97.2
WP_009911346.1\|625162_625654_-	bacteriophage gp35-type protein	A8ATX4	Listeria_phage	1.1e-90	98.8
WP_009911345.1\|625684_625993_-	helix-turn-helix transcriptional regulator	A8ATX5	Listeria_phage	7.8e-47	98.0
WP_003731220.1\|626141_626393_+	helix-turn-helix transcriptional regulator	A8ATX6	Listeria_phage	7.6e-40	100.0
626341:626356	attL	NA	NA	NA	NA
WP_003727743.1\|626396_626663_+	hypothetical protein	A0A059T7Q1	Listeria_phage	2.5e-41	100.0
WP_003735007.1\|626886_627081_+	hypothetical protein	A0A059T6E5	Listeria_phage	1.3e-26	100.0
WP_003769996.1\|627092_627377_+	hypothetical protein	A0A0B5D168	Listeria_phage	1.6e-46	98.9
WP_003733634.1\|627416_627653_+	hypothetical protein	A0A059T5E9	Listeria_phage	3.3e-37	100.0
WP_003769995.1\|627649_627931_+	hypothetical protein	Q9T180	Listeria_phage	1.4e-39	96.8
WP_025370647.1\|628116_628359_-	hypothetical protein	A0A059T7Q3	Listeria_phage	1.5e-37	98.8
WP_046811268.1\|628422_629202_+	antirepressor	A0A059T6E7	Listeria_phage	3.8e-138	96.1
WP_031644191.1\|629323_629860_+	hypothetical protein	Q9T177	Listeria_phage	7.2e-80	88.1
WP_031644193.1\|629852_630068_+	hypothetical protein	Q9T176	Listeria_phage	1.8e-26	87.3
WP_031644195.1\|630175_630364_+	hypothetical protein	A8ATY3	Listeria_phage	1.3e-28	98.4
WP_031644196.1\|630595_631555_+	hypothetical protein	Q9T173	Listeria_phage	8.7e-153	83.1
WP_031644198.1\|631557_632373_+	recombinase RecT	Q9T172	Listeria_phage	1.7e-144	94.8
WP_031644200.1\|632392_633325_+	DnaD domain-containing protein	A8ATY7	Listeria_phage	2.6e-149	89.3
WP_031690742.1\|633321_634035_+	SAM-dependent DNA methyltransferase	A8ATD5	Listeria_phage	7.7e-130	97.9
WP_031644274.1\|634045_634990_+\|integrase	site-specific integrase	A8ATD6	Listeria_phage	4.5e-178	98.4
WP_023548471.1\|635002_635683_+	hypothetical protein	A8ATD7	Listeria_phage	3.3e-122	97.8
WP_031670092.1\|635679_636228_+	DUF1642 domain-containing protein	A0A059T7S4	Listeria_phage	3.7e-71	75.3
WP_046811267.1\|636224_636746_+	hypothetical protein	A0A059T7V5	Listeria_phage	2.4e-32	47.8
WP_046811266.1\|636916_637597_+	pentapeptide repeat-containing protein	A0A060AFJ6	Listeria_phage	1.2e-34	94.7
WP_046811265.1\|637800_638001_+	hypothetical protein	NA	NA	NA	NA
WP_020830692.1\|637997_638399_+	hypothetical protein	A0A059T6C9	Listeria_phage	1.9e-53	76.7
WP_020830693.1\|638395_638674_+	hypothetical protein	NA	NA	NA	NA
WP_046811264.1\|638673_639153_+	single-stranded DNA-binding protein	A0A059T5E0	Listeria_phage	5.4e-79	94.4
WP_039382681.1\|639184_639490_+	hypothetical protein	A8ATZ8	Listeria_phage	1.9e-37	83.2
WP_003759675.1\|639486_639627_+	BH0509 family protein	A8ATZ9	Listeria_phage	4.7e-15	87.0
WP_031644573.1\|639592_639997_+	endodeoxyribonuclease	A8AU00	Listeria_phage	2.7e-71	98.5
WP_031644575.1\|640125_640290_+	hypothetical protein	A8ASQ0	Listeria_phage	7.4e-20	94.4
WP_003735131.1\|640308_640743_+	hypothetical protein	A8ASQ1	Listeria_phage	4.3e-75	99.3
WP_009911405.1\|641137_641437_+	phage protein	A0A2H4JBC0	uncultured_Caudovirales_phage	3.8e-14	40.7
WP_010990212.1\|641463_641727_+	hypothetical protein	A0A0S2MYE7	Enterococcus_phage	1.7e-34	78.2
WP_010990213.1\|641784_642327_+\|terminase	terminase small subunit	A8ASJ1	Listeria_phage	5.4e-91	98.9
WP_010990214.1\|642295_643627_+\|terminase	PBSX family phage terminase large subunit	A8ASJ2	Listeria_phage	1.1e-259	98.6
WP_014601086.1\|643639_645130_+\|portal	phage portal protein	Q9T1C0	Listeria_phage	3.3e-284	99.6
WP_039393322.1\|645135_646275_+	hypothetical protein	A0A0B5D147	Listeria_phage	4.9e-203	96.8
WP_014601084.1\|646353_646944_+	scaffold protein	Q9T1B8	Listeria_phage	7.7e-75	91.5
WP_046811263.1\|646943_647945_+	hypothetical protein	A0A059T6D4	Listeria_phage	8.2e-186	99.4
WP_010989952.1\|647963_648359_+	hypothetical protein	A0A059T5E3	Listeria_phage	4.8e-65	97.7
WP_031645712.1\|648358_648721_+	hypothetical protein	A0A0B5D151	Listeria_phage	1.8e-58	91.7
WP_031645711.1\|648720_649059_+	hypothetical protein	A0A059T7W4	Listeria_phage	7.0e-57	97.3
WP_031645710.1\|649058_649466_+	hypothetical protein	A0A0B5CU21	Listeria_phage	1.5e-66	98.5
WP_012582409.1\|649468_649906_+	hypothetical protein	A0A0B5CYN3	Listeria_phage	4.2e-78	98.6
WP_045552940.1\|649835_650168_+	Ig-like virion protein	Q9T1B0	Listeria_phage	1.5e-30	70.9
WP_003769943.1\|650220_650643_+	hypothetical protein	Q9T1A9	Listeria_phage	5.9e-69	97.9
WP_003735024.1\|650648_651248_+	hypothetical protein	A0A0B5CTW0	Listeria_phage	1.9e-76	72.0
WP_046811262.1\|651258_656622_+	tape measure protein	Q9T1A7	Listeria_phage	0.0e+00	97.3
WP_031645707.1\|656623_657442_+\|tail	phage tail family protein	Q9T1A6	Listeria_phage	3.8e-149	93.4
WP_046811261.1\|657450_658476_+	phage minor structural protein	Q9T1A5	Listeria_phage	1.5e-182	88.6
WP_046811260.1\|658476_659505_+	hypothetical protein	Q9T1A4	Listeria_phage	3.3e-190	98.5
WP_046811259.1\|659504_660578_+\|plate	phage baseplate upper protein	Q9T1A3	Listeria_phage	9.1e-191	95.8
WP_003727798.1\|660589_660907_+	hypothetical protein	Q9T1A2	Listeria_phage	1.3e-49	92.4
WP_003722524.1\|660911_661070_+	hypothetical protein	Q9T1A1	Listeria_phage	6.0e-19	100.0
WP_003722523.1\|661097_661463_+	hypothetical protein	Q9T1A0	Listeria_phage	7.4e-12	100.0
WP_003722522.1\|661475_661757_+\|holin	holin	A8ASL4	Listeria_phage	3.4e-41	94.6
661623:661638	attR	NA	NA	NA	NA
WP_031644606.1\|661756_662608_+	peptidase M15	A0A059T7Y8	Listeria_phage	1.4e-138	93.3
WP_023548524.1\|662872_663040_+	hypothetical protein	NA	NA	NA	NA
WP_003725136.1\|663437_663671_+	hypothetical protein	A8ATC5	Listeria_phage	1.2e-34	92.2

DBSCAN-SWA_3

1190576 : 1198862

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003729814.1\|1190576_1191869_+	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	2.5e-17	33.0
WP_003726214.1\|1191949_1192663_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3F9V5	Synechococcus_phage	2.0e-40	38.3
WP_003722248.1\|1192674_1192920_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_003726212.1\|1192923_1193607_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_031644866.1\|1193599_1195819_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.7e-159	41.0
WP_003722245.1\|1195803_1197231_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.1e-53	34.6
WP_003726210.1\|1197249_1198299_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	3.2e-63	44.4
WP_003726209.1\|1198295_1198862_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	8.3e-26	36.4

DBSCAN-SWA_4

1689957 : 1864731

210

Listeria_phage(80.43%)

protease,holin,tail,head,terminase,plate,portal,tRNA,capsid,integrase

attL 1818022:1818045|attR 1863291:1863314

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003726415.1\|1689957_1691220_-\|protease	RIP metalloprotease RseP	NA	NA	NA	NA
WP_003726414.1\|1691233_1692376_-	1-deoxy-D-xylulose-5-phosphate reductoisomerase	NA	NA	NA	NA
WP_003727496.1\|1692390_1693179_-	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_003727497.1\|1693192_1693951_-	isoprenyl transferase	R9W0U9	Flavobacterium_phage	4.4e-22	42.1
WP_003723450.1\|1694181_1694739_-	ribosome recycling factor	NA	NA	NA	NA
WP_003723449.1\|1694738_1695467_-	UMP kinase	NA	NA	NA	NA
WP_003727498.1\|1695759_1696134_+	hypothetical protein	NA	NA	NA	NA
WP_012681273.1\|1696111_1697317_+	helicase SNF2	L0P6E9	Lactobacillus_phage	7.0e-91	46.6
WP_003731336.1\|1697306_1698611_+	DUF3440 domain-containing protein	A0A220GKF8	Streptococcus_phage	1.2e-133	52.1
WP_003726669.1\|1698620_1699127_+	ParB-like nuclease domain-containing protein	A0A220GKT8	Streptococcus_phage	1.4e-56	66.7
WP_003726668.1\|1699148_1699880_+	class I SAM-dependent methyltransferase	A0A1X9I6N4	Streptococcus_phage	2.3e-81	58.0
WP_003726667.1\|1699928_1700168_-	YneF family protein	NA	NA	NA	NA
WP_009928628.1\|1700388_1702383_-	transketolase	NA	NA	NA	NA
WP_003727501.1\|1702529_1702757_-	DUF896 domain-containing protein	NA	NA	NA	NA
WP_003734518.1\|1702850_1703180_-	cell division suppressor protein YneA	NA	NA	NA	NA
WP_009928625.1\|1703335_1703950_+	transcriptional repressor LexA	A0A1B2APZ1	Phage_Wrath	9.3e-15	62.1
WP_003734519.1\|1703980_1704505_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_023550496.1\|1704538_1705834_-	arsenic transporter	A0A2H4PQU3	Staphylococcus_phage	2.2e-146	62.1
WP_003723435.1\|1705977_1707312_-	type I glutamate--ammonia ligase	A0A1V0SJ53	Klosneuvirus	2.0e-06	26.4
WP_003719570.1\|1707382_1707751_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_003727505.1\|1707952_1709179_-	methionine gamma-lyase family protein	NA	NA	NA	NA
WP_012681271.1\|1709171_1710395_-	GTPase HflX	NA	NA	NA	NA
WP_003719566.1\|1710505_1710739_-	RNA chaperone Hfq	NA	NA	NA	NA
WP_003726658.1\|1710860_1711778_-\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_003723738.1\|1711904_1713581_-	glycerol-3-phosphate dehydrogenase/oxidase	NA	NA	NA	NA
WP_023550494.1\|1713813_1714512_-	glycerophosphodiester phosphodiesterase	A0A0S2MYI4	Enterococcus_phage	8.4e-12	31.9
WP_003727507.1\|1714724_1716611_+	acetyltransferase	B5WZU0	Pseudomonas_phage	3.8e-43	32.2
WP_023550490.1\|1716643_1718452_-	class 1 internalin InlK	NA	NA	NA	NA
WP_003726814.1\|1719080_1719548_-	S-ribosylhomocysteine lyase	NA	NA	NA	NA
WP_010958880.1\|1719630_1722090_-	DNA topoisomerase IV subunit A	G3M9Z5	Bacillus_virus	1.1e-101	31.8
WP_003727510.1\|1722086_1724054_-	DNA topoisomerase IV subunit B	G3M9Z3	Bacillus_virus	5.1e-123	42.5
WP_003727511.1\|1724234_1724642_-	CoA-binding protein	NA	NA	NA	NA
WP_003726698.1\|1724799_1725396_+	glycerol-3-phosphate 1-O-acyltransferase PlsY	NA	NA	NA	NA
WP_003726697.1\|1725437_1726310_-	aldose 1-epimerase family protein	NA	NA	NA	NA
WP_003724130.1\|1726312_1726624_-	hypothetical protein	NA	NA	NA	NA
WP_023550487.1\|1726646_1727066_-	acyl-CoA thioesterase	NA	NA	NA	NA
WP_003726695.1\|1727168_1727948_-	GTP-sensing pleiotropic transcriptional regulator CodY	NA	NA	NA	NA
WP_003727514.1\|1727968_1729378_-\|protease	ATP-dependent protease ATPase subunit HslU	W6AS21	Erwinia_phage	7.5e-44	27.8
WP_003724001.1\|1729391_1729931_-\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_023550485.1\|1729951_1730854_-	tyrosine recombinase XerC	A0A142K7N4	Mycobacterium_phage	1.8e-14	29.5
WP_003726401.1\|1731136_1732441_-\|tRNA	FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO	NA	NA	NA	NA
WP_003727517.1\|1732503_1734582_-	type I DNA topoisomerase	A0A1V0SB35	Catovirus	5.4e-107	37.5
WP_003727518.1\|1734854_1735715_-	DNA-protecting protein DprA	NA	NA	NA	NA
WP_003727519.1\|1735848_1736634_-	ribonuclease HII	G4YAY0	Emiliania_huxleyi_virus	6.7e-26	37.6
WP_003726396.1\|1736630_1737494_-	ribosome biogenesis GTPase YlqF	NA	NA	NA	NA
WP_003727520.1\|1737503_1738046_-	type I signal peptidase SipZ	NA	NA	NA	NA
WP_003726394.1\|1738147_1738717_-	type I signal peptidase SipY	NA	NA	NA	NA
WP_003726393.1\|1738751_1739318_-	type I signal peptidase SipX	NA	NA	NA	NA
WP_003723886.1\|1739436_1740696_-\|protease	ATP-dependent protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.4e-145	63.2
WP_003723884.1\|1740880_1742164_-	trigger factor	NA	NA	NA	NA
WP_003727521.1\|1742278_1743217_-	hypothetical protein	NA	NA	NA	NA
WP_003731300.1\|1743478_1744144_-	hypothetical protein	NA	NA	NA	NA
WP_003727523.1\|1744159_1744693_-\|protease	matrixin family metalloprotease	NA	NA	NA	NA
WP_052750972.1\|1744975_1745197_-	hypothetical protein	A8ATX1	Listeria_phage	1.4e-21	89.7
WP_052750971.1\|1745193_1745427_-	hypothetical protein	A8ATC5	Listeria_phage	1.1e-32	87.0
WP_003731544.1\|1745736_1746102_+	hypothetical protein	A8ATJ4	Listeria_phage	6.4e-56	94.2
WP_023559354.1\|1746115_1746319_+	hypothetical protein	A8ATJ3	Listeria_phage	2.6e-30	95.5
WP_046811238.1\|1746346_1746568_+	helix-turn-helix transcriptional regulator	A8ATJ2	Listeria_phage	9.3e-34	97.3
WP_003731541.1\|1746629_1747463_-	N-acetylmuramoyl-L-alanine amidase	A0A1S7FZ94	Listeria_phage	2.5e-47	43.8
WP_031648624.1\|1747465_1747720_-\|holin	phage holin	A8ATJ0	Listeria_phage	9.4e-38	95.2
WP_031648623.1\|1747730_1747946_-	LysM peptidoglycan-binding domain-containing protein	A8ATI9	Listeria_phage	1.8e-26	93.0
WP_003731538.1\|1747965_1748412_-	hypothetical protein	A8ATI8	Listeria_phage	1.7e-63	95.9
WP_003731537.1\|1748387_1748834_-	hypothetical protein	A8ATI7	Listeria_phage	9.3e-73	97.3
WP_003731536.1\|1749019_1749361_-	hypothetical protein	A8ATI5	Listeria_phage	1.5e-43	93.5
WP_003731535.1\|1749366_1750095_-	hypothetical protein	A8ATI4	Listeria_phage	2.7e-130	93.4
WP_003731534.1\|1750116_1750758_-	hypothetical protein	A8ATI3	Listeria_phage	4.5e-113	99.1
WP_046811237.1\|1750747_1751899_-\|plate	baseplate J/gp47 family protein	A8ATI2	Listeria_phage	2.4e-165	77.0
WP_003731532.1\|1751891_1752254_-	DUF2634 domain-containing protein	A8ATI1	Listeria_phage	2.0e-41	70.0
WP_046811236.1\|1752250_1752589_-	hypothetical protein	A8ATI0	Listeria_phage	9.2e-49	86.6
WP_046811279.1\|1752589_1753396_-	hypothetical protein	A8ATH9	Listeria_phage	6.1e-131	86.9
WP_003731529.1\|1753401_1753773_-	hypothetical protein	A8ATH8	Listeria_phage	5.4e-50	77.0
WP_046811235.1\|1753772_1754321_-	LysM peptidoglycan-binding domain-containing protein	A8ATH7	Listeria_phage	7.1e-83	84.5
WP_046811234.1\|1754326_1759357_-	peptidoglycan DD-metalloendopeptidase family protein	A8ATH6	Listeria_phage	0.0e+00	74.6
WP_031642248.1\|1759358_1759571_-	hypothetical protein	A8ATH5	Listeria_phage	1.9e-28	91.4
WP_049961612.1\|1759533_1759890_-	hypothetical protein	A8ATH4	Listeria_phage	2.3e-58	97.5
WP_049961613.1\|1759942_1760341_-	hypothetical protein	A8ATH3	Listeria_phage	4.0e-67	99.2
WP_046811233.1\|1760357_1761353_-	DUF3383 family protein	A8ATH2	Listeria_phage	3.5e-181	99.4
WP_031648613.1\|1761357_1761840_-	hypothetical protein	A8ATH1	Listeria_phage	1.1e-82	96.9
WP_046811232.1\|1761829_1762204_-	hypothetical protein	A8ATH0	Listeria_phage	8.0e-62	95.2
WP_031648611.1\|1762203_1762803_-	hypothetical protein	A8ATG9	Listeria_phage	3.7e-109	98.5
WP_031648610.1\|1762802_1763138_-	DUF4054 domain-containing protein	A8ATG8	Listeria_phage	3.6e-53	99.1
WP_039378284.1\|1763149_1763536_-	hypothetical protein	A8ATG7	Listeria_phage	2.1e-65	98.4
WP_046811231.1\|1763558_1764464_-	DUF2184 domain-containing protein	A8ATG6	Listeria_phage	9.7e-162	97.0
WP_046811230.1\|1764484_1764934_-	hypothetical protein	A8ATG5	Listeria_phage	1.0e-74	98.0
WP_039378288.1\|1764933_1766043_-	DUF2213 domain-containing protein	A8ATG4	Listeria_phage	9.4e-175	99.5
WP_046811229.1\|1766258_1767668_-\|head	phage head morphogenesis protein	A8ATG2	Listeria_phage	5.6e-265	98.9
WP_046811228.1\|1767660_1769046_-	DUF1073 domain-containing protein	A8ATG1	Listeria_phage	9.7e-262	98.0
WP_046811227.1\|1769059_1770520_-\|terminase	phage terminase large subunit	A8ATG0	Listeria_phage	1.0e-277	95.1
WP_046811226.1\|1770497_1771382_-	hypothetical protein	A8ATF9	Listeria_phage	2.2e-126	92.9
WP_003731509.1\|1771423_1771711_-	hypothetical protein	A0A0S2MYE7	Enterococcus_phage	9.9e-20	55.4
WP_003731508.1\|1771748_1771979_-	hypothetical protein	A8ATN7	Listeria_phage	3.7e-33	98.7
WP_003731507.1\|1772108_1772306_-	hypothetical protein	A8ATN6	Listeria_phage	5.2e-28	100.0
WP_046811225.1\|1772353_1773691_-	chromosome partitioning protein ParB	A8ATN5	Listeria_phage	7.2e-246	94.8
WP_046811224.1\|1773763_1774240_-	hypothetical protein	A0A1P8BMT7	Lactococcus_phage	5.5e-07	30.2
WP_046811222.1\|1774553_1775321_-	Rha family transcriptional regulator	A8ATN0	Listeria_phage	9.8e-139	98.4
WP_003731502.1\|1775333_1775756_-	hypothetical protein	A8ATM9	Listeria_phage	6.3e-71	100.0
WP_046811221.1\|1775836_1776397_-	phage protein	A8ATM8	Listeria_phage	4.5e-101	95.7
WP_046811220.1\|1776408_1776663_-	DUF3850 domain-containing protein	A8ATM7	Listeria_phage	5.9e-32	82.5
WP_046811219.1\|1776655_1776856_-	hypothetical protein	NA	NA	NA	NA
WP_046811218.1\|1776852_1777185_-	hypothetical protein	A8ATZ5	Listeria_phage	4.5e-08	93.1
WP_003731497.1\|1777184_1777373_-	hypothetical protein	NA	NA	NA	NA
WP_003731496.1\|1777391_1777775_-	preprotein translocase subunit YajC	A8ATZ3	Listeria_phage	2.4e-53	88.2
WP_046811217.1\|1777915_1778170_-	hypothetical protein	A0A059T6G3	Listeria_phage	7.4e-27	74.4
WP_046811216.1\|1778166_1778544_-	hypothetical protein	NA	NA	NA	NA
WP_046811215.1\|1778560_1779922_-	hypothetical protein	A8ATM0	Listeria_phage	2.4e-249	94.7
WP_046811214.1\|1779918_1780341_-	hypothetical protein	A8ATL9	Listeria_phage	6.1e-50	88.6
WP_046811213.1\|1780493_1780874_-	hypothetical protein	A8ATL7	Listeria_phage	1.6e-65	95.2
WP_046811212.1\|1780914_1781535_-	hypothetical protein	A8ATL6	Listeria_phage	6.1e-107	98.1
WP_046811211.1\|1781554_1781992_-	RusA family crossover junction endodeoxyribonuclease	A8ATL5	Listeria_phage	8.5e-71	91.0
WP_046811210.1\|1781972_1782212_-	hypothetical protein	A8ATL4	Listeria_phage	3.6e-31	98.6
WP_046811277.1\|1782168_1782390_-	hypothetical protein	A8ATL3	Listeria_phage	1.2e-28	85.3
WP_041918379.1\|1782376_1782577_-	hypothetical protein	A8ATL2	Listeria_phage	4.0e-28	89.4
WP_031648583.1\|1782573_1783389_-	ATP-binding protein	A8ATL1	Listeria_phage	4.1e-143	99.3
WP_003731482.1\|1783312_1784230_-	DUF4373 domain-containing protein	A8ATL0	Listeria_phage	2.2e-169	100.0
WP_046811209.1\|1784241_1784937_-	MBL fold metallo-hydrolase	A8ATK9	Listeria_phage	4.3e-125	97.4
WP_046811208.1\|1784936_1785668_-	phage recombination protein Bet	A8ATK8	Listeria_phage	6.0e-77	61.4
WP_046811207.1\|1785671_1787615_-	AAA family ATPase	A8ATK7	Listeria_phage	0.0e+00	98.3
WP_046811206.1\|1787601_1787943_-	hypothetical protein	A8ATK6	Listeria_phage	6.7e-23	51.3
WP_046811205.1\|1787960_1788188_-	hypothetical protein	A8ATK5	Listeria_phage	5.2e-32	98.7
WP_046811204.1\|1788365_1788650_-	hypothetical protein	A8ATK4	Listeria_phage	9.2e-26	54.2
WP_046811203.1\|1789128_1789653_-	hypothetical protein	A8ATK1	Listeria_phage	6.6e-86	90.8
WP_046811202.1\|1789729_1789915_-	helix-turn-helix transcriptional regulator	A8ATK0	Listeria_phage	5.8e-29	100.0
WP_046811201.1\|1790073_1790502_+	helix-turn-helix transcriptional regulator	A8ATJ9	Listeria_phage	2.0e-72	99.3
WP_046811200.1\|1790518_1790938_+	ImmA/IrrE family metallo-endopeptidase	A8ATJ8	Listeria_phage	3.4e-77	98.6
WP_046811199.1\|1790984_1791377_+	hypothetical protein	A8ATJ7	Listeria_phage	2.6e-55	94.6
WP_046811198.1\|1791466_1792882_+	recombinase family protein	A0A1L2JY12	Aeribacillus_phage	3.0e-117	47.1
WP_003723563.1\|1793198_1793594_+	helix-turn-helix transcriptional regulator	A9D9J6	Lactobacillus_prophage	1.3e-14	57.4
WP_003734523.1\|1793673_1794813_+\|protease	PrsW family intramembrane metalloprotease	NA	NA	NA	NA
WP_003726720.1\|1794959_1795790_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	3.6e-46	42.4
WP_023550483.1\|1795773_1797021_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	7.2e-107	51.8
WP_031644533.1\|1797046_1797961_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_003726717.1\|1798149_1798614_+	hypothetical protein	NA	NA	NA	NA
WP_003726723.1\|1798652_1799114_-	NUDIX hydrolase	NA	NA	NA	NA
WP_003727531.1\|1799231_1800716_+	PTS system trehalose-specific EIIBC component	NA	NA	NA	NA
WP_014929571.1\|1800734_1802381_+	alpha,alpha-phosphotrehalase	NA	NA	NA	NA
WP_003726055.1\|1802411_1803125_-	trehalose operon repressor	NA	NA	NA	NA
WP_003726054.1\|1803742_1804591_+	YitT family protein	NA	NA	NA	NA
WP_003726053.1\|1804657_1804852_+	hypothetical protein	NA	NA	NA	NA
WP_003726052.1\|1804891_1805551_-	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_003726051.1\|1805755_1806961_+	MFS transporter	NA	NA	NA	NA
WP_003726050.1\|1806957_1807203_+	hypothetical protein	NA	NA	NA	NA
WP_003727535.1\|1807240_1807717_-	8-oxo-dGTP diphosphatase	NA	NA	NA	NA
WP_003726048.1\|1807884_1808148_-	DUF3116 domain-containing protein	NA	NA	NA	NA
WP_023550481.1\|1808172_1809585_-	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	4.9e-51	32.0
WP_009928848.1\|1809708_1809969_+	hypothetical protein	NA	NA	NA	NA
WP_003726045.1\|1810000_1810600_-	histidine phosphatase family protein	A0A1X9IGJ2	Lactococcus_phage	1.3e-29	41.0
WP_003726044.1\|1810764_1811172_+	glyoxalase/bleomycin resistance/extradiol dioxygenase family protein	NA	NA	NA	NA
WP_003726043.1\|1811308_1811902_+	hypothetical protein	NA	NA	NA	NA
WP_003726042.1\|1811944_1813303_-	DUF1254 domain-containing protein	NA	NA	NA	NA
WP_046811197.1\|1813425_1817556_-	LapB repeat-containing protein	NA	NA	NA	NA
1818022:1818045	attL	NA	NA	NA	NA
WP_009928186.1\|1818224_1818587_-	hypothetical protein	NA	NA	NA	NA
WP_003726037.1\|1818692_1819166_-	hypothetical protein	NA	NA	NA	NA
WP_031672409.1\|1819858_1820050_-	hypothetical protein	A8ATC6	Listeria_phage	1.7e-28	98.4
WP_014930932.1\|1820046_1820280_-	hypothetical protein	A8ATX0	Listeria_phage	2.3e-35	94.8
WP_025370597.1\|1820758_1821460_-	DUF3800 domain-containing protein	R4IBV1	Listeria_phage	6.4e-129	97.8
WP_025370596.1\|1821607_1822315_-	M15 family metallopeptidase	A8ATW4	Listeria_phage	1.0e-129	97.9
WP_003723294.1\|1822314_1822596_-\|holin	phage holin	A8ATW3	Listeria_phage	3.0e-45	100.0
WP_003733957.1\|1822595_1822901_-	hypothetical protein	A0A059T5E6	Listeria_phage	1.8e-43	100.0
WP_046811196.1\|1822951_1824043_-	hypothetical protein	A0A059T7R4	Listeria_phage	1.7e-189	91.8
WP_026749927.1\|1824032_1826327_-	hypothetical protein	A0A059T7Y6	Listeria_phage	0.0e+00	99.2
WP_153648966.1\|1826339_1827989_-\|tail	phage tail protein	A0A059T682	Listeria_phage	0.0e+00	98.7
WP_153648967.1\|1827981_1832901_-\|tail	phage tail tape measure protein	A0A059T5F4	Listeria_phage	0.0e+00	97.1
WP_046811195.1\|1833116_1833449_-	hypothetical protein	A0A059T7R2	Listeria_phage	1.5e-51	96.4
WP_014929552.1\|1833519_1834107_-\|tail	phage tail protein	A0A059T7Y4	Listeria_phage	2.9e-106	98.5
WP_046811194.1\|1834127_1834511_-	hypothetical protein	A0A059T681	Listeria_phage	1.1e-66	98.4
WP_012951550.1\|1834507_1834909_-	hypothetical protein	A0A059T5F3	Listeria_phage	2.1e-68	100.0
WP_014929549.1\|1834905_1835271_-	hypothetical protein	A0A059T6F2	Listeria_phage	2.9e-64	100.0
WP_014930914.1\|1835254_1835554_-	hypothetical protein	A0A059T7R0	Listeria_phage	5.3e-48	100.0
WP_014930913.1\|1835740_1836892_-\|capsid	phage major capsid protein	A0A059T678	Listeria_phage	6.3e-214	100.0
WP_046811193.1\|1836918_1837716_-\|protease	Clp protease ClpP	A0A059T5F2	Listeria_phage	1.1e-143	99.6
WP_023548926.1\|1837712_1838843_-\|portal	phage portal protein	A8AT96	Listeria_phage	1.7e-203	93.1
WP_109217207.1\|1838854_1840498_-\|terminase	terminase large subunit	A0A059T7Q8	Listeria_phage	0.0e+00	98.2
WP_014929542.1\|1840494_1840851_-	hypothetical protein	A0A059T7Y1	Listeria_phage	4.5e-46	97.0
WP_009928009.1\|1840899_1841214_-	HNH endonuclease	A8ATF8	Listeria_phage	3.8e-57	99.0
WP_009917711.1\|1841574_1842318_-	DUF559 domain-containing protein	NA	NA	NA	NA
WP_009917712.1\|1842415_1842841_-	DUF722 domain-containing protein	A0A059T6H4	Listeria_phage	8.0e-74	100.0
WP_003731655.1\|1842853_1843081_-	hypothetical protein	NA	NA	NA	NA
WP_003731657.1\|1843325_1843595_-	hypothetical protein	NA	NA	NA	NA
WP_046811274.1\|1843591_1844125_-	DUF3310 domain-containing protein	A0A059T7T5	Listeria_phage	1.1e-80	82.5
WP_039389924.1\|1844235_1844505_-	hypothetical protein	W0GBM0	Listeria_phage	5.3e-15	73.6
WP_046811192.1\|1844501_1844822_-	VRR-NUC domain-containing protein	W0G8N0	Listeria_phage	5.8e-53	95.3
WP_046811191.1\|1845114_1847388_-	DNA primase	A8ATF3	Listeria_phage	0.0e+00	94.7
WP_015987323.1\|1847410_1847893_-	DUF669 domain-containing protein	A8ATF2	Listeria_phage	4.9e-88	100.0
WP_109217206.1\|1847915_1849172_-	DEAD/DEAH box helicase	R4IBK4	Listeria_phage	9.5e-224	97.0
WP_023553843.1\|1849235_1849925_-	AAA family ATPase	R4IDY8	Listeria_phage	4.8e-129	98.3
WP_003731665.1\|1849944_1850424_-	siphovirus Gp157 family protein	R4IBM0	Listeria_phage	7.6e-57	76.7
WP_012951535.1\|1850425_1850809_-	hypothetical protein	A8ATE8	Listeria_phage	5.3e-61	92.9
WP_003731670.1\|1851312_1851579_-	hypothetical protein	NA	NA	NA	NA
WP_003731671.1\|1851568_1851799_-	hypothetical protein	NA	NA	NA	NA
WP_003731672.1\|1851795_1852029_-	hypothetical protein	NA	NA	NA	NA
WP_012951531.1\|1852047_1852677_-	hypothetical protein	A0A191KBJ8	Streptococcus_virus	1.1e-66	58.4
WP_012951530.1\|1852677_1853157_-	hypothetical protein	NA	NA	NA	NA
WP_046811189.1\|1853709_1854423_-	pentapeptide repeat-containing protein	A8ATE4	Listeria_phage	1.9e-35	89.0
WP_046811284.1\|1854596_1855001_-	hypothetical protein	R4ICD6	Listeria_phage	1.2e-42	66.4
WP_031643753.1\|1854987_1855194_-	hypothetical protein	NA	NA	NA	NA
WP_023548959.1\|1855355_1855544_-	hypothetical protein	NA	NA	NA	NA
WP_023548961.1\|1855536_1856112_-	DUF1642 domain-containing protein	Q8W5X2	Listeria_phage	1.0e-31	42.9
WP_009928035.1\|1856108_1856789_-	hypothetical protein	A8ATD7	Listeria_phage	1.1e-120	96.5
WP_023548963.1\|1856801_1857746_-\|integrase	site-specific integrase	A8ATD6	Listeria_phage	2.7e-178	99.0
WP_023548965.1\|1857756_1858470_-	SAM-dependent DNA methyltransferase	A8ATD5	Listeria_phage	5.4e-131	98.3
WP_023548967.1\|1858993_1859179_-	hypothetical protein	A0A059T7Z3	Listeria_phage	4.4e-29	98.4
WP_015987310.1\|1859181_1859424_-	hypothetical protein	A8ATD2	Listeria_phage	1.4e-43	100.0
WP_009929536.1\|1859425_1859629_-	helix-turn-helix transcriptional regulator	A0A059T5F8	Listeria_phage	3.1e-28	100.0
WP_025370565.1\|1859694_1860012_+	hypothetical protein	NA	NA	NA	NA
WP_046811187.1\|1860472_1860796_+	helix-turn-helix transcriptional regulator	Q8W5Y0	Listeria_phage	1.2e-37	72.0
WP_052750973.1\|1860812_1861265_+	ImmA/IrrE family metallo-endopeptidase	A0A059T7S0	Listeria_phage	2.3e-71	84.0
WP_012951517.1\|1861316_1861973_+	DUF4352 domain-containing protein	NA	NA	NA	NA
WP_046811186.1\|1862118_1863273_+\|integrase	site-specific integrase	A0A059T688	Listeria_phage	2.8e-214	97.7
WP_003726034.1\|1863558_1864083_-	metallophosphoesterase	NA	NA	NA	NA
1863291:1863314	attR	NA	NA	NA	NA
WP_009928777.1\|1864119_1864731_-	XTP/dITP diphosphatase	Q66YC8	Euphorbia_ringspot_virus	8.7e-05	28.0

DBSCAN-SWA_5

1984876 : 1992299

Hokovirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023550418.1\|1984876_1986433_-	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	6.0e-18	29.2
WP_009929871.1\|1986561_1986966_-	PTS lactose transporter subunit IIBC	NA	NA	NA	NA
WP_009929872.1\|1987026_1987335_-	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_023550416.1\|1987347_1988172_-	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	1.3e-67	52.2
WP_003721509.1\|1988183_1989674_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	9.5e-114	49.7
WP_026747136.1\|1989882_1990896_-	glycosyltransferase	A0A1V0SAH6	Catovirus	1.8e-10	31.2
WP_003727002.1\|1990910_1991894_-	glycosyltransferase family 2 protein	A0A1V0SAH6	Catovirus	2.0e-11	33.8
WP_003730941.1\|1991915_1992299_-	glycerol-3-phosphate cytidylyltransferase	A0A1V0SGE7	Hokovirus	1.4e-16	40.7

DBSCAN-SWA_6

2988546 : 2995073

Streptococcus_pyogenes_phage(33.33%)

tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003734720.1\|2988546_2989365_-\|tail	phage tail family protein	A0A060AFE1	Staphylococcus_phage	7.2e-39	35.0
WP_046811173.1\|2989361_2991230_-	membrane protein	A0A097PAU2	Streptococcus_pyogenes_phage	4.5e-20	45.8
WP_003740367.1\|2991216_2991621_-	hypothetical protein	NA	NA	NA	NA
WP_003721745.1\|2991662_2991965_-	hypothetical protein	NA	NA	NA	NA
WP_003721744.1\|2992012_2992525_-\|tail	phage major tail protein, TP901-1 family	A0A097PBF4	Streptococcus_pyogenes_phage	1.2e-47	62.7
WP_003728212.1\|2992537_2992927_-	DUF5072 domain-containing protein	NA	NA	NA	NA
WP_003731177.1\|2993206_2993623_-	hypothetical protein	A8ASQ1	Listeria_phage	6.5e-20	37.9
WP_009927883.1\|2993634_2994063_-	hypothetical protein	NA	NA	NA	NA
WP_003721740.1\|2994279_2994615_+	helix-turn-helix transcriptional regulator	A0A2H4JAR9	uncultured_Caudovirales_phage	4.0e-20	52.5
WP_003728215.1\|2994620_2995073_+	ImmA/IrrE family metallo-endopeptidase	A0A059T7S0	Listeria_phage	4.0e-31	47.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP045750

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP045749

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection