CRISPRimmunity

Please click to download your results

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP045736	Aeromicrobium sp. MF47 plasmid p001, complete sequence	0 crisprs	NA	0	0	0	0
NZ_CP045737	Aeromicrobium sp. MF47 chromosome, complete genome	11 crisprs	cas3,DEDDh,csa3,WYL,DinG,casR	2	1	0	0

Cas Category Instructions

Results visualization

1. NZ_CP045737

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP045737_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045737_1

119748-119846

Orphan

Consensus_repeat	Method
ACGTGAGGGCGCGGAGGCGAACCGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045737_1

>merge|NZ_CP045737|1|119748-119846|CRISPRCasFinder
ACGTGAGGGCGCGGAGGCGAACCGCGTGGGTTCGTCCGCCTCGCTGCGCTCACGGTCGCTTCGCTCCCTGGCGAACGGGAGGGCGCGGAGGCGAACCGC

>NZ_CP045737|1|1|119748-119846|CRISPRCasFinder
ACGTGAGGGCGCGGAGGCGAACCGC	GTGGGTTCGTCCGCCTCGCTGCGCTCACGGTCGCTTCGCTCCCTGGCGA
ACGGGAGGGCGCGGAGGCGAACCGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045737.1\|WP_153651320.1\|129704_131456_+\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|224099
NZ_CP045737.1\|WP_153651314.1\|121568_122279_-\|FCD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224715
NZ_CP045737.1\|WP_153651312.1\|118199_119219_+\|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274928
NZ_CP045737.1\|WP_153651319.1\|128530_129703_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|226361
NZ_CP045737.1\|WP_153651306.1\|110346_111231_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|224137
NZ_CP045737.1\|WP_153651304.1\|107889_109101_+\|DUF1972-domain-containing-protein	unknown	unknown	gnl\|CDD\|340858
NZ_CP045737.1\|WP_153651322.1\|132758_133223_-\|MaoC-family-dehydratase	unknown	unknown	gnl\|CDD\|239534
NZ_CP045737.1\|WP_153651311.1\|117722_118157_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045737.1\|WP_153651318.1\|126389_128528_+\|CoA-binding-protein	unknown	unknown	gnl\|CDD\|223972
NZ_CP045737.1\|WP_153651315.1\|122509_123829_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377179
NZ_CP045737.1\|WP_153651309.1\|113193_114276_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|340831
NZ_CP045737.1\|WP_153654897.1\|116206_117646_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341047
NZ_CP045737.1\|WP_153651321.1\|131523_132675_+\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|224753
NZ_CP045737.1\|WP_153651305.1\|109273_110374_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|379337
NZ_CP045737.1\|WP_153651310.1\|114647_116006_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224799
NZ_CP045737.1\|WP_153654898.1\|120369_121533_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340883
NZ_CP045737.1\|WP_153651317.1\|124900_126382_+\|MmgE/PrpD-family-protein	unknown	unknown	gnl\|CDD\|377179
NZ_CP045737.1\|WP_153651316.1\|123851_125003_+\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|224871
NZ_CP045737.1\|WP_153651307.1\|111656_112196_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223515
NZ_CP045737.1\|WP_153651308.1\|112209_113181_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|340831

Protein	Function_ID	Function_description	E-value
NZ_CP045737.1\|WP_153651320.1\|129704_131456_+\|ABC-transporter-permease-subunit	gnl\|CDD\|224099	COG1178, ThiP, ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism].	2.36396e-80
NZ_CP045737.1\|WP_153651314.1\|121568_122279_-\|FCD-domain-containing-protein	gnl\|CDD\|224715	COG1802, GntR, Transcriptional regulators [Transcription].	7.00838e-43
NZ_CP045737.1\|WP_153651312.1\|118199_119219_+\|LLM-class-flavin-dependent-oxidoreductase	gnl\|CDD\|274928	TIGR04027, Luciferase-like_monooxygenase, putative FMN-dependent luciferase-like monooxygenase, KPN_01858 family. This protein family consists of luciferase-like monooxygenases (LLM), and include KPN_01858 from Klebsiella pneumoniae as a representative member. Most are from species that lack F420 biosynthesis, so the family is likely to bind FMN as its cofactor. This family is closely associated with a binding protein-dependent ABC transporter, suggesting a role in catabolism. [Unknown function, Enzymes of unknown specificity].	2.04276e-35
NZ_CP045737.1\|WP_153651319.1\|128530_129703_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|226361	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism].	1.69184e-134
NZ_CP045737.1\|WP_153651306.1\|110346_111231_+\|glycosyltransferase	gnl\|CDD\|224137	COG1216, COG1216, Predicted glycosyltransferases [General function prediction only].	1.7583e-20
NZ_CP045737.1\|WP_153651304.1\|107889_109101_+\|DUF1972-domain-containing-protein	gnl\|CDD\|340858	cd04955, GT4-like, glycosyltransferase family 4 proteins. This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in certain bacteria and Archaea.	8.27556e-59
NZ_CP045737.1\|WP_153651322.1\|132758_133223_-\|MaoC-family-dehydratase	gnl\|CDD\|239534	cd03450, NodN, NodN (nodulation factor N) contains a single hot dog fold similar to those of the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit. Rhizobium and related species form nodules on the roots of their legume hosts, a symbiotic process that requires production of Nod factors, which are signal molecules involved in root hair deformation and meristematic cell division. The nodulation gene products, including NodN, are involved in producing the Nod factors, however the role played by NodN is unclear.	2.416e-73
NZ_CP045737.1\|WP_153651315.1\|122509_123829_+\|hypothetical-protein	gnl\|CDD\|377179	pfam03972, MmgE_PrpD, MmgE/PrpD family. This family includes 2-methylcitrate dehydratase EC:4.2.1.79 (PrpD) that is required for propionate catabolism. It catalyzes the third step of the 2-methylcitric acid cycle.	2.08977e-56
NZ_CP045737.1\|WP_153651318.1\|126389_128528_+\|CoA-binding-protein	gnl\|CDD\|223972	COG1042, COG1042, Acyl-CoA synthetase (NDP forming) [Energy production and conversion].	4.17841e-89
NZ_CP045737.1\|WP_153651309.1\|113193_114276_-\|glycosyltransferase	gnl\|CDD\|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	1.29903e-12
NZ_CP045737.1\|WP_153654897.1\|116206_117646_+\|MFS-transporter	gnl\|CDD\|341047	cd17504, MFS_MMR_MDR_like, Methylenomycin A resistance protein (also called MMR peptide)-like multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of putative multidrug resistance (MDR) transporters including Chlamydia trachomatis antiseptic resistance protein QacA_2, and Serratia sp. DD3 Bmr3. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. This subfamily belongs to the Methylenomycin A resistance protein (also called MMR peptide) and similar multidrug resistance (MDR) transporters (MMR-like MDR transporter) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.21184e-78
NZ_CP045737.1\|WP_153651321.1\|131523_132675_+\|extracellular-solute-binding-protein	gnl\|CDD\|224753	COG1840, AfuA, ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism].	2.96444e-29
NZ_CP045737.1\|WP_153651305.1\|109273_110374_+\|glycosyltransferase	gnl\|CDD\|379337	pfam13692, Glyco_trans_1_4, Glycosyl transferases group 1.	1.73541e-15
NZ_CP045737.1\|WP_153651310.1\|114647_116006_-\|hypothetical-protein	gnl\|CDD\|224799	COG1887, TagB, Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane].	2.19979e-08
NZ_CP045737.1\|WP_153654898.1\|120369_121533_-\|MFS-transporter	gnl\|CDD\|340883	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters. This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.098e-25
NZ_CP045737.1\|WP_153651317.1\|124900_126382_+\|MmgE/PrpD-family-protein	gnl\|CDD\|377179	pfam03972, MmgE_PrpD, MmgE/PrpD family. This family includes 2-methylcitrate dehydratase EC:4.2.1.79 (PrpD) that is required for propionate catabolism. It catalyzes the third step of the 2-methylcitric acid cycle.	1.36138e-119
NZ_CP045737.1\|WP_153651316.1\|123851_125003_+\|acyl-CoA-dehydrogenase	gnl\|CDD\|224871	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism].	2.20677e-93
NZ_CP045737.1\|WP_153651307.1\|111656_112196_+\|hypothetical-protein	gnl\|CDD\|223515	COG0438, RfaG, Glycosyltransferase [Cell envelope biogenesis, outer membrane].	7.72498e-06
NZ_CP045737.1\|WP_153651308.1\|112209_113181_-\|glycosyltransferase	gnl\|CDD\|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	3.01363e-05

>NZ_CP045737.1|WP_153651312.1|118199_119219_+|LLM-class-flavin-dependent-oxidoreductase
MKNVGFLSFGHYQAVPGSQTRTASDVMLQSIDLAVAAEELGLDGAYFRVHHFARQLASPFPLLAAVGARTSRIEIGTGVIDMRYENPLYMAEDAAAADLISEGRLQLGISRGSPETALRGYEAFGHVPAEGTSDADMARAHAELFRAAIAGAGLVESDPRMTGRSVTLPVMPQAPGLADRIWWGSGTRATAEWTAQQGMNLMSSTLLTEDTGVPFDQLQLEQIELFRSAWAAAGWEREPRVSVSRSVIPVLDAQDRAWFGERSGEDQVGHLDGGLARFGKSYVGEPDVLAEELAADVAVQAADSLLLTVPNQLGVDYNARLLSALADYVLPAIGWKPRT
>NZ_CP045737.1|WP_153651311.1|117722_118157_+|hypothetical-protein
MRTRSQVLAPAVLVLAGALTACGGSDAKDSKASPEPTRATTTATPDVKDGVGADADPALVKLVCAPDKDGVWSARMTLVNSTDERAGYLARVAVLTTATSDVLGRQTLRVELGPGERAVVPFDRLAEGGKEGRSCEPRVVRMDD
>NZ_CP045737.1|WP_153654897.1|116206_117646_+|MFS-transporter
MTFAVLAVSVASFALLQSLVTPVLSEIQVDLNTDQTTVTWVLTAYLLSASVFTPIIGRIGDKVGKEKLLVVALVGLAIGSIIAALATSIGPMIVARIIQGVGGGVLPLAFGIIRDEFPEKKIPGAVGIIASLAAVGAGVGLVLAGPIVEALNYHWLFWIPGIVTAVAAVAAFFVVPASPVRTPGKISVLPAVLLSAWLVCLLLALSQGRSWGWTSGRVLGLIVAAVVLAVAWVMVEERSESPLIDMTMMRLPAVWTTNLVALLVGFAMYASFGFLPQFTQTPTEAGYGFGASITESGLILLPSSVTMFVVGLLSGTFVRLIGPKTVVVIGSLIAASSMAILAFAHDEKWELYVANAIMGVGVGLIFACLSNLIVAAVPPEQTGVASGMNANIRTIGGSVGAAVMASIVTASVFPNGLPKESGYTNGFIMLTIAFVVAALVALLIPRVKREVIEEHLVGEPEHPELGMVAAGTLVGDKSE
>NZ_CP045737.1|WP_153651310.1|114647_116006_-|hypothetical-protein
MILVAVVVLLAALSTGLLVRRSLTARPPLAAHVPGQPTWLSPAPPLRFRAWAIAAAVLTAITVACILFAPAFQVAAALLAAAVLGLMAAIAGRYASGCRESQEAVDAFAPRLAVPYAGKVGVHIGMWSPWIERTGIPWVIVARTPALFRELAAMYPGTPIVQGTIPASVTGAFYPHGAASNADFIAGSAATHVFLGHGDSDKPLSASDRVLQYDLVAVAGQAAIDRFAAAGLAIPADKIRVIGRPQTEGILPGRKRRSRPPVVLYAPTWRHADDSLNVSSLAVADQIVQALLDRGCTVHFRRHFAGQNHVEAEAMIVRVNELLEADHERTGRPHQWGAEAMERPLIDAFNDVDAMVSDVSGIVVDFMASTKPLVMYAAQYADPDEFRATHPTAQAAYVIDRDLAQLDKALDAALGKDPLAAVRAERADYYLGGPDRAEPAARFIALLEELGR
>NZ_CP045737.1|WP_153651309.1|113193_114276_-|glycosyltransferase
MRSLQETAIRVLPELRAVQVEQGLLMSPAMHWFFDTNYDLFETSIPPGFERMSLRRAAWRLLSSDASVLEVPEPLWARFLPQNVTLVVAWRLGGLLRLRNRKARTYAIENNSPGEALFGRSIPWPLDVFVRFALGAFMRMFFERVALGTPAAADSYATLPFFRRIEHSMILGLPTPSLGADEAEADPNTAIFVGHLDARKGLPELMSAWSEVEQRLPSASLVVVGAGPLRESVEKWVTARPGSRRYLGQLPHDRILSVVGQAAVVVAPSVRARRWREQVGLPIEEGLSMGRTIVTTSETGLADWLHQHGHSIIASDALETDLSRALVDALTYPIEPSSVLDSLPTRHGRLVADSWLHRAY
>NZ_CP045737.1|WP_153651308.1|112209_113181_-|glycosyltransferase
MSRGHVLVALGAGSRAGDAAWMNSGVATRVIHLDHAAPSGRRLRSRILGMGIDSLLIALKTAFSGVRGPVLAANPWVGVSLRLLGWRHVSVTGIYAEAGSRNHRVLRRLLGSSSVVTMVESEARSWREAGGRAIAVRYGNTLQYPPRVPKVNSAVRIFVGGSSDRDHQVLEDLIARVQSSQFEVHLTITLDEQPASWSNGSSTITRTGRLTNSEFGAQMSQADVVFLPLVDGSRAAGHMVAVGALETGAPVITTRSGGMDGYVDGTFVATLDEHADLLDQLVETGLAWRGRETEVREHWAREYSLEAYVVRVGEALSQLEAAR
>NZ_CP045737.1|WP_153651307.1|111656_112196_+|hypothetical-protein
MTLLNHPLLTEREQVAPRNNAGRPSVLVFGQFKPDRDIDLMAQLSESMGSGVDFRVSGRGWPDIAGWDMDRRFVPELEIDPLIRSASAVLIPYRRFFQSGVAIRCLEQGTPVVGPAESSLAEVLLDDRLLGKDEDVSSWVCAIRAAIDTNREDWAKVRRRYLEGTDAQWTEWVDGFKKR
>NZ_CP045737.1|WP_153651306.1|110346_111231_+|glycosyltransferase
MAARIRGIMKGLQEVQTVVVHHNSIETLRRCLASLLAQGLPADRIHVVDNSEMLGDVSEVASSAHSAIRVSSIANRGYAAAINYGVISIPSDSEASLLLVVTHEVTFSEGAVENMVRELHSDPSLKAVGPALRNASTGASWSEGGFLTRVLSLPRHQDGRTRGRGATLWLDGAAVLYRLEELQRHPMREDYFLYMEEVDYHLQINRRGGSVKVVQDAQAEQSSHGTPAYFLARNVQLFQASWGTLGLRSVAVLWECSKCFVRGLRAGAPLATLRQLAAGYGAGRKVLAERRTGL
>NZ_CP045737.1|WP_153651305.1|109273_110374_+|glycosyltransferase
MSAASSIRVLPELRSIQVERAEVLTPALHLYFAENYDLSRTSVPKSFRRVGLIGAVAVLARSRAVTLELPEPLWLREFPRTATMALVWRLRGLLSASRREVVMYAIENNDLETLVGKRSRVAHVLVVTALRIFISHFVDRIAFGSPSAASAYSALISGDVDGDGGVVESTKYAQFTELPAPRNSIDLDTSSTDAIFVGELSVRKGMEHLMAAWELVERQSPGARLRVVGTGPLTEKVVAWCSASPQTRHYMGFVEHGALDAHIEQCAVLVAPSRRAGRWREQIGLPIVEGLASGLTIVTSRDTGLAAWLEAQGHQVIRSDYQVVELAGALLEALGSPIPKKTVIGSLPLEPQRIRADRWLHESGAS
>NZ_CP045737.1|WP_153651304.1|107889_109101_+|DUF1972-domain-containing-protein
MLKQTGGSRPKRVAIIGTRGYPSYYGGFETAVRKLAPHLADHGWDVTVYGRKGQLKTDDPTLDGRIRSVETAGIDSNSLSTLTFGLSACLHAFLRKPDVVLVMNVANGYWLPLLKMRRIPVVVNVDGIEWHRAKWGRVAKAMFLWGARLTAKFADHLVFDARAIGEFWRKEFGRTGTFIPYGGETVGELPVEAGLSKHKYALMVARFVPENTISEFVLAAEKISRTHDVVLVGSAPEGHPIREEVASLAERNSRVYWMGHISDDRRLLALWQHAGAYFHGHSVGGTNPALVQAMTVGSPVVARDTVYNREVLADAGMFCEPTPEAIARSVISMIEDSGDYRERSIARAAEQYSWSGVCVAYESLLRSVLPTSETKTEPSAGAKNLFSASADSSGYGSVESDLR
>NZ_CP045737.1|WP_153654898.1|120369_121533_-|MFS-transporter
MVLISIASHAVLNGVRTLISYRALALGGDALSVGIVTASFAVLPLLVALPIGRAVDRGHGMRVLRGGLVLTVGAVVLAATSTNLGVLAGASALLGFGQILHTIACQSLIPLWSPPELMDKRFGQLTLGVSAGQFLGFPLAGIVATLSNSGAGGDGTLKTTFSLIVMAAVATAAVPLAYAFSPASRAVRSRREQVGTQQSSLTILRQPGMKPAMYSSMTVLSGLDLLTAYVPVLGEHLGLSVGMVTFLLTMRALASVLSRIALPALLVHVGRRWLIVSATLVSAIPVALIPLTTNVVALSAAMLVIGFFWGIGQPLTMVWVTTVSHRDNRATALSLRLAGNRIAQFAVPLGAGAVAGATGVGVIFYLTAGLLASSGLLSLSATRRMPD
>NZ_CP045737.1|WP_153651314.1|121568_122279_-|FCD-domain-containing-protein
MASDDVAIPGSRTAYVLERLRADLRNGLINPGDQLRQVELARRYGVSATPVREALRVLEADGMIDYHTHRGATVRDYTPQMATDLYRMRAEMESLAVTVAMERMTPEVLAGIRVANEELLAATDSAASSAELSRLNKALHFAIYQATSPVMIECIEMLWSRFTPSVTLWSVSGFTTELRHDHEAILSAIEDGDAERASRAMHEHIMHACDLRATHAALRPAGPVSDAAGDGSPQAP
>NZ_CP045737.1|WP_153651315.1|122509_123829_+|hypothetical-protein
MSQLDSLDATERERWGVLVADAWGLMAAGAEAPGLRAMLAASAELGDGDIVVPYTPRTWSPQGAAAAASALIHAWDFDDTHDTAVVHTAAIAVPAALAAAQRRNASGRSFADGIVVGVQALSRLGGLVGPRAGVIRTAGLGAPAAAAAAAATWGLDRAGIENAMSLAVGVSLAPGSRQAVVDSSLAKRVQPGLAVQAGLYAAALALNGVEGPRGWLTGDHGLLPGADVTVADVLDGPFAGAELAIKPYPACRYGHAAIAAAEQLYRAHGAQTDDKLVVRLPEGASYAMVARPYADRGEPIIDAQFSVPWQVASIWTSGRYDVATLAGPDVVDPVIASAARAVEVRQDLPASTVMSGATVELHRAGVVHVAESPMPGGPEAPLDRSAVDAKIRSCLTVAGLDPDAESRRIWELVDGVADLSPADLRRTLTEFAPARQTVA
>NZ_CP045737.1|WP_153651316.1|123851_125003_+|acyl-CoA-dehydrogenase
MDFTLTPDQTALVDSVTKLAEKEFAPQAFKRTEFAWDSLKVLADNDLTGLTLSPEMGGQGASLLDAVLVMMAITKVCPHSADALQASNFGAIRQVAKFGSDRVKEEVLPKLLAGEAIVTAGMSEPEAGSALTELRTTARYDGDEVVLNGQKIYNSHGPDASYSVVWCRFGPTTKDIGAVLVPFDAPGFSRGKRELHMSGESHCQLYFDECRVPKEYVLADSGAIRSMMSTFGVERMGNASRAIALAETAYDRAVEHAKTRTQFGKNLCEFQGLQWKFADMRVQLDAAKLLLFRAVSDAESGSPDPTYASIAKLHANETAFKVANEALQIFGASGYSQEFPMEYIVRRTRGWMIAGGSMEILRNTIAQSVFGRRFDQRAGAVAK
>NZ_CP045737.1|WP_153651317.1|124900_126382_+|MmgE/PrpD-family-protein
MDDRRRLDGDPAQHDRAVGLRPSFRPACRSCGQVSDVQMNLTAQLADWAAAQADRPLDAAARHHVRRLWVDYLAAVIPGSSAPTSRQVAAHAAIQYPGDQAEAVGTGRLSALGAALVNGTSAHCLEVDDGYTPGSVHPSTVIFPAVLAAAQAAGSDDEITERALAVGLEVVCRLAAAGHPATWRNHFHNTPVTGVLGSAVAVAVLHRLDAEQIEHALGIAASHAGGLFAFLGQAAEVKRLHPGKAARDGIASAELAAAGVTGPRGVLEAPHGYIDAFARGDFDNETLVGDLGEKWAFLDTYVKPYPCCRHLHGPIDAVRALKAEHQVKAGDVESVTVRTYTVASHHAARTVDEFLDAQMSIPFAVTVALAFDEVGLTEFGDDVRHDATIRALVDRVSVVADADIDAVYPRLRPAIVEITLRDGSVLTHRVDTPYGEPSNPVSDEDMTGKLVRLAGPIIGSDRAAALAEQTWTAPTHRTTLDVALSTSETPGSE
>NZ_CP045737.1|WP_153651318.1|126389_128528_+|CoA-binding-protein
MTTVLSQTARPTVGSAMLHPRSVAIIGASDDITKTTARPLAFLRKAGFNGRVYPVNPRRETVLGERAWPSIASLPETPDHVFVVADTRFVVDAVAECGARGVPVVTILSGGFAEAGEEGAVRQAELLKVAREHGVRLIGPNSIGVVNPGAGLMLTANAAFAEEAIPVGRTFVASQSGSVIGALMTRAKAVGIGFAGLVSTGSEIDLTLGEICAATVDDPEVDAYCLFLESLDNAASLAAFAELAHERGKPVTVYKLGRSDAAAELSVSHTGALAGEDSEASAFFEACGFVRVENFESLIEAGAVQRRLMGTIRDADAPRVGVITSTGGGAALAVDELEMRGIALTRPSAETFARINEAGIAVSESLIIDLTLAGTRHDKVLNVLGILEDSEEFDLLVFVIGSSARLNPELAASAIEEFADRRLPVVAWALPDALETLQRLHRAGVPAFRTVESCAEAVAATLRSRAPRGEALAGVKTPAAGGTRVLDEQQSAEVLKQVGARFPQSLVLGPGEPVPADLAYPVVVKVLSDAIAHKSDVGGVEVGIRDADGLEQARRRILDSVARHRPDVLADTVLVQEMVVDPVQEMLVGYRVSDTVGPLVVLAAGGVTVELYGDSAVQMAPVDRDTAAGMIERVKATALSRGYRSAPTGDLDALADLVVAVSRLAIERPDVVEAEINPVAVLRDTEGIIALDALVTVLADQGEDSTTTTDES
>NZ_CP045737.1|WP_153651319.1|128530_129703_+|ATP-binding-cassette-domain-containing-protein
MDVTISNLSLSYGDFRAVKNLSLDIADGESIVMLGQSGCGKTSTMRCIAGLEDPSGGSISIGGRTVFDAESRTRVPANKRNVGLVFQSYAVWPHLTVLENVAFPLKQQKLGKDEIRRKALETLRIVGLEAVAENGASALSGGQMQRVALARSLAMEPAVMLLDEPLSNLDARLRDDLRVELRRLQIELGLTSVYVTHDQGEALALADRIAVMQHGRITQLASPTEIYERPASATIAAFLGVLNIFPVGRPKGHHVDSVDHDMQFVTETAVDHDVLSSVSIRPEHVRVSTERDDHGVSGGVNTWEGRVEVTVFQGATTRCAVRLDAGPVLETTVPGSAINVFHPGDRVFVHVDARDVKVLPNEVPELASGFPTKWTDSAPLAASGAAQGGE
>NZ_CP045737.1|WP_153651320.1|129704_131456_+|ABC-transporter-permease-subunit
MASTLVTAPAPDPAPPAAPPGPARISFWRTWLGSGLLIAFLAFLILIPAGFVLLAAMTGSVPRPGNISFSPTFDNFSVLGVPEVRKAFLNSMIMAISATLLAALIGGGLAFLAARTDIRVPKFVYLVGLMPMFLPSYVGALAWSILGSPNAGLLNIGLRDLGLPAFIDLYSMPGLIMVFAIYYAPYTFLMVHAALSLMSPDLEEAAHIHGATTRTMLRRISFPLALPAVLGSAILTFTLIFENFPVAQVLGTPGGVDTLPTFIFRLLNATPSRGNESAAIAVVLVAVVIIATMLQNRVIAKRSYTTVSGKGVRNKKIALGRWRTPAFIAVLVFFTLSIVLPLLALLVTAGQTSPYMSTLGDLFEPGGFDLGIIGEVARSADFLSATSNSVVVSLFAATAGTILAFLCGYTVYRTKVGGRKLIEGISMVPLAIPAVVLGMGLLWTWLVMPIPLYGTLAVMAIAFVAVQSPQGFRGIASSIMQTDRDLEDSAVMLGASRSRAILAVTVPLMKVGLLSTFLLLLMLSMRELTVPLFLYTTDTKILSITIYDAFENGGALRGAAAMSLLYCLFMFILSYIPRRLAQK
>NZ_CP045737.1|WP_153651321.1|131523_132675_+|extracellular-solute-binding-protein
MRTIPKSVAVAAAAVMSLSLAACGGSSSSGGAGGSASAAEEILAMPEIDDSDGLVIGGEKVADADLLKAARKEGSVAWYTASGAESAEVTAARFEAETGVKVKMTRMPSGKLAERVLSESGAGRLDAGVVTITDPVIAEEFASKGVYAPYKVASYDTVSKVDGVVYEDGLYYAPYYSAYAFSYNNQVVKEADAPKDWADLTDPKWKGKVGIVHAGAGGTVQGLAQFQEERLGKDYWGKLAALKPRIFDTTSTQLEALARGEIHVATSGFNSTYGAEIAGAPITLVVPPGGVSGTYNMQGVTKAGLDSAAAKLFQDWSMSSSGQQFAAAQGFVAARTDIPATKTGDYTLPTADSPDFELYTPEDARELGADIVARWNKAYGYGG
>NZ_CP045737.1|WP_153651322.1|132758_133223_-|MaoC-family-dehydratase
MSAAPVVIDSAEVLHGLVGVELGPSRPLVVTQERIDAFADATGDHQWIHVDPERAADGPYGGTIAHGYLTLSLVSGLSDDLFVVELGSARINYGVDRARFPSPVPVGSTLRASCTVVDVVDRDSSWLVTYRFTMQVEGQDRPACVVDKLSLILA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP045737_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045737_2

572366-572458

Orphan

Consensus_repeat	Method
CCGAGGATGAGGGTTCTGGGTCGCTGGGG	CRISPRCasFinder

1 spacers

WYL

The CRISPR arrays of NZ_CP045737_2

>merge|NZ_CP045737|2|572366-572458|CRISPRCasFinder
CCGAGGATGAGGGTTCTGGGTCGCTGGGGTTGCCACAAACCCTCATCGTCCGTCCGGTCCCGACCCGAGGAAGAGGGTTCTGGGTCGCTGGGG

>NZ_CP045737|2|2|572366-572458|CRISPRCasFinder
CCGAGGATGAGGGTTCTGGGTCGCTGGGG	TTGCCACAAACCCTCATCGTCCGTCCGGTCCCGAC
CCGAGGAAGAGGGTTCTGGGTCGCTGGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045737.1\|WP_153651697.1\|573760_574441_-\|uracil-DNA-glycosylase	unknown	unknown	gnl\|CDD\|235376
NZ_CP045737.1\|WP_153651699.1\|576992_578102_-\|alanine-dehydrogenase	unknown	unknown	gnl\|CDD\|240630
NZ_CP045737.1\|WP_153651689.1\|562564_564892_-\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|238923
NZ_CP045737.1\|WP_153651700.1\|578190_578700_+\|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224439
NZ_CP045737.1\|WP_153651687.1\|560611_561796_-\|DUF222-domain-containing-protein	unknown	unknown	gnl\|CDD\|367155
NZ_CP045737.1\|WP_153651702.1\|579790_580375_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|224584
NZ_CP045737.1\|WP_153651693.1\|569967_570933_-\|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|225253
NZ_CP045737.1\|WP_153654937.1\|574437_575529_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340951
NZ_CP045737.1\|WP_153651695.1\|571442_572273_-\|formate-dehydrogenase-accessory-sulfurtransferase-FdhD	unknown	unknown	gnl\|CDD\|234823
NZ_CP045737.1\|WP_153651703.1\|580379_580871_-\|ASCH-domain-containing-protein	unknown	unknown	gnl\|CDD\|119345
NZ_CP045737.1\|WP_153651698.1\|575652_576873_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340887
NZ_CP045737.1\|WP_153651701.1\|578713_579763_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP045737.1\|WP_153651692.1\|567255_567606_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|366940
NZ_CP045737.1\|WP_153651688.1\|561872_562568_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045737.1\|WP_153651690.1\|564875_566213_-\|aspartate-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|99743
NZ_CP045737.1\|WP_153651704.1\|580901_582326_-\|aminotransferase-class-V-fold-PLP-dependent-enzyme	unknown	unknown	gnl\|CDD\|223154
NZ_CP045737.1\|WP_153651694.1\|571022_571439_+\|DUF1761-family-protein	unknown	unknown	gnl\|CDD\|369962
NZ_CP045737.1\|WP_153651696.1\|572572_573706_-\|AI-2E-family-transporter	unknown	unknown	gnl\|CDD\|223701
NZ_CP045737.1\|WP_153651691.1\|566468_567182_+\|VOC-family-protein	unknown	unknown	gnl\|CDD\|380093
NZ_CP045737.1\|WP_153651686.1\|559676_560492_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP045737.1\|WP_153651699.1\|576992_578102_-\|alanine-dehydrogenase	gnl\|CDD\|240630	cd05305, L-AlaDH, Alanine dehydrogenase NAD-binding and catalytic domains. Alanine dehydrogenase (L-AlaDH) catalyzes the NAD-dependent conversion of pyruvate to L-alanine via reductive amination. Like formate dehydrogenase and related enzymes, L-AlaDH is comprised of 2 domains connected by a long alpha helical stretch, each resembling a Rossmann fold NAD-binding domain. The NAD-binding domain is inserted within the linear sequence of the more divergent catalytic domain. Ligand binding and active site residues are found in the cleft between the subdomains. L-AlaDH is typically hexameric and is critical in carbon and nitrogen metabolism in micro-organisms.	0
NZ_CP045737.1\|WP_153651693.1\|569967_570933_-\|WYL-domain-containing-protein	gnl\|CDD\|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	3.19168e-44
NZ_CP045737.1\|WP_153651689.1\|562564_564892_-\|EAL-domain-containing-protein	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	1.43001e-94
NZ_CP045737.1\|WP_153651687.1\|560611_561796_-\|DUF222-domain-containing-protein	gnl\|CDD\|367155	pfam02720, DUF222, Domain of unknown function (DUF222). This family is often found associated to the N-terminus of the HNH endonuclease domain pfam01844. The function of this domain is uncertain. This family has been called the 13E12 repeat family.	4.88909e-19
NZ_CP045737.1\|WP_153651702.1\|579790_580375_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	6.35847e-27
NZ_CP045737.1\|WP_153651697.1\|573760_574441_-\|uracil-DNA-glycosylase	gnl\|CDD\|235376	PRK05254, PRK05254, uracil-DNA glycosylase; Provisional.	2.04625e-125
NZ_CP045737.1\|WP_153654937.1\|574437_575529_-\|MFS-transporter	gnl\|CDD\|340951	cd17393, MFS_MosC_like, Membrane protein MosC and similar proteins of the Major Facilitator Superfamily of transporters. The gene encoding Sinorhizobium meliloti membrane protein MosC is part of the mos locus, which encodes the biosynthesis of the rhizopine 3-O-methyl-scyllo-inosamine. MosC belongs to the bacterial fucose permease, eukaryotic Major facilitator superfamily domain-containing protein 4 (FucP/MFSD4) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.03363e-77
NZ_CP045737.1\|WP_153651695.1\|571442_572273_-\|formate-dehydrogenase-accessory-sulfurtransferase-FdhD	gnl\|CDD\|234823	PRK00724, PRK00724, formate dehydrogenase accessory sulfurtransferase FdhD.	3.87449e-111
NZ_CP045737.1\|WP_153651703.1\|580379_580871_-\|ASCH-domain-containing-protein	gnl\|CDD\|119345	cd06553, ASCH_Ef3133_like, ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as an RNA-binding domain during coactivation, RNA-processing and the regulation of prokaryotic translation.	3.85569e-61
NZ_CP045737.1\|WP_153651698.1\|575652_576873_+\|MFS-transporter	gnl\|CDD\|340887	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MdtH and similar multidrug resistance (MDR) transporters from bacteria and archaea, many of which remain uncharacterized. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtH confers resistance to norfloxacin and enoxacin. MdtH-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.37565e-10
NZ_CP045737.1\|WP_153651701.1\|578713_579763_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	4.58341e-08
NZ_CP045737.1\|WP_153651692.1\|567255_567606_+\|hypothetical-protein	gnl\|CDD\|366940	pfam02148, zf-UBP, Zn-finger in ubiquitin-hydrolases and other protein.	2.41087e-11
NZ_CP045737.1\|WP_153651700.1\|578190_578700_+\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	2.46433e-37
NZ_CP045737.1\|WP_153651690.1\|564875_566213_-\|aspartate-aminotransferase-family-protein	gnl\|CDD\|99743	cd06450, DOPA_deC_like, DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and glutamate decarboxylase (GDC). DDC is active as a dimer and catalyzes the decarboxylation of tyrosine. GDC catalyzes the decarboxylation of glutamate and HDC catalyzes the decarboxylation of histidine.	7.20354e-69
NZ_CP045737.1\|WP_153651704.1\|580901_582326_-\|aminotransferase-class-V-fold-PLP-dependent-enzyme	gnl\|CDD\|223154	COG0076, GadB, Glutamate decarboxylase and related PLP-dependent proteins [Amino acid transport and metabolism].	9.72208e-76
NZ_CP045737.1\|WP_153651694.1\|571022_571439_+\|DUF1761-family-protein	gnl\|CDD\|369962	pfam08570, DUF1761, Protein of unknown function (DUF1761). Family of conserved fungal and bacterial membrane proteins with unknown function.	2.4004e-06
NZ_CP045737.1\|WP_153651696.1\|572572_573706_-\|AI-2E-family-transporter	gnl\|CDD\|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	1.47618e-58
NZ_CP045737.1\|WP_153651691.1\|566468_567182_+\|VOC-family-protein	gnl\|CDD\|380093	pfam18029, Glyoxalase_6, Glyoxalase-like domain. This entry comprises a diverse set of domains related to the Glyoxalase domain. The exact specificity of these proteins is uncertain.	9.28697e-19

>NZ_CP045737.1|WP_153651695.1|571442_572273_-|formate-dehydrogenase-accessory-sulfurtransferase-FdhD
MAGRLTRRTRVTRFDPTAATVQREDTLAVEEPLEIRVNGRSFSVTMRSPGDDFDLVAGFLVSEGVIWSAEQLVSLRFCAGTDENGLQTFNVVDAQLSADTAPPDLSLERHVYTSSSCGICGTASIEAVEKATHFGRVDDDQTWPASLIGSLPDRLREHQKVFDRTGGVHAAGLFDAAGELVCLREDVGRHNAVDKVVGWALREGRLPLRGMSLQVSGRASFELVQKAHMAGIPVLAAVSAPSSLAVEHAEVAGMTLVGFSRGGAFNAYAGAHRISE
>NZ_CP045737.1|WP_153651694.1|571022_571439_+|DUF1761-family-protein
MFDVIPELNWLAILLSTGVLAVLGGIYFGALVPRQYVAVLGRQDLPAPEPGLVTYAGPVTCMFVVVVTNAVLMAALGVESIGDALAFGAIVGVGYLVAMAFNIAINPSFPRPLAYGLLNTPYFLGGSLVSCAILQLMG
>NZ_CP045737.1|WP_153651693.1|569967_570933_-|WYL-domain-containing-protein
MTTTSSRLLSLLSLLQARRDWPGAVLAHRLDVSARTVRRDVDRLRELGYPVVASKGPDGGYRLEAGTELPPLLFDDEQAVALAVALRLAATSGASIDEAAARALATVRQVMPARLRHRIDAVEVTAVGPPETPPVDTGLLAELSTAIRRREVLRFDYASPSGARGPGPRRAEPLHLVARSGRWYLVGWDLEREDWRTYRVDRIAPRTPNGPRFEPREVPGGDLAAFVNGRFRGSDGTTDWPCRGEVVVHRPAAEVSPYVSDGAVEPLGADRCRLVQGAWSWIGLAALLGRHDAEIEVVGPPELAAAFEALAARYARAGSPT
>NZ_CP045737.1|WP_153651692.1|567255_567606_+|hypothetical-protein
MPTSQDGIAPTVPPSGDGCAECLAANGWWFHLRRCAECGHVGCCDSSPGQHASAHFHETGHPVMQSFEPGESWLWDFRTAQAFSGVELAAPTSRPADQPAPGPAGSVPADWQSRLH
>NZ_CP045737.1|WP_153651691.1|566468_567182_+|VOC-family-protein
MPSTLVALCFGAREPAVLAQFWARLLDRETTAGPDGSTDVEPAGAADLRIRYVPFDHPRRGPNQTHLHLTSTSPEHQLATVDRALALGGSHLDVGQLPEEAHIVLADPEGNEFCVIEADNGFLADTAPLGELACDGSAAVGRFWSGALGWPLVWDQDEETAIQSPAGGTKISWGGPPFRDKRGRNRLYLALAPVGATELEIDRLIALGAARAEHLDAELGGAALTDPGANELVLLEP
>NZ_CP045737.1|WP_153651690.1|564875_566213_-|aspartate-aminotransferase-family-protein
MHDFALQDRQVLGELASWIADRRDAPVPPRPAGAAALPEVTGSGIGIRATWAALRDVLLPSSFPTDHPRYLAFVGGSPTPAAVIADAALSAAAVYGGSELEAGDVVAAERVAIRWLCDTIGYPEQSHGVFVAGGSLANLSALVTARHQRVTERGGMPGIIVASASTHSSVRAAAGIMGCQVLSVGTPDRPLHADELTAVLDGLDPDDVVAVVANAGATNTGAIDALREIAECCEVRGIWLHVDAAYGGAALLAPGRRAEFDGIQHADSVTIDPHKWLFTPFDCAAVLYLDPAIARAAHQQRAVYLEAVEDDGADNPADYAAHLTRRARGVPVWASLVANGTDAYVDAVEQCLAVAEYAAKQIETLPHLEIVTEPHLSVVLFRRRGWTAEHYSAWSAEIQANGLALVTPTTFDGESVLRLCFVNPLTSTDDVDLVLKTLECHAPNG
>NZ_CP045737.1|WP_153651689.1|562564_564892_-|EAL-domain-containing-protein
MRPTDESVRSRVNVAQAIVAPLPWAVMTTGLVVNEITKPAADVKTPEVVLTSLAIFFPLLVLRLALVSFLHPGRRTTLLLLLASIAAWSVGSISVNAARVDGQTQFPAPGEWLFLLSYLGMAGYLLRDVDRRQSRPARAWLDIIIICGGTACLASLLLVTPVRAVSHQEGSSLLLALIYPMADMILALVVLGQSLLQTRIDRRKSWMTGMAFVLLAVADSGLALQGSATTYDFGTLSYALWGAGFSLLVAAACRPAQTVIRAVPRSGDTFVLVGAGVIALAVLTVRPDQTLGYYMLPPAMLTLAAVGARLALALRDANRANDAFALSQTDDLTKLPNRRAVRAWLSEGLADRTPLALMLLDLDGFKEINDSLGHRAGDTVLMLVGVRLREAVELPARVARLGGDEFAIIMRTTDEIELMETAQSVLAELAKPISVEGIEISPAGSIGVTVAGPGDQDGGEVMRRADVAMYQAKNSGLGAALYDAELDEFTRSRLKLAEELRRGIAEGQIEVWYQPQVDAATMRVCGLEALVRWRHPTQGVISPVTFLPAARRAGLMGKLSESVVTQVVDDLQARHEAGVDLNVAINCAPPELLGPTFLPHLFAAIDRVKVPPDRLVLEVTEDSFLADPQHTREILLELRDHGVQISIDDYGTGFSSLAYLRNLPVQELKIDRTLIGDVATDDRSRMIVASTIQLAHALEMRIVAEGVENAADLAALVAMGIDEVQGYHIGRPMPPWQIDAWLSERAAADRELVPSPSAASETELDRPEQERKESR
>NZ_CP045737.1|WP_153651688.1|561872_562568_-|hypothetical-protein
MTSAPLRFVFDPVGDELAAARQCEADVFLEAYGNTAEEFEVEYGAYEDSTGFMTILEDDGRAVAVARFIAPGPAGLKTLNDVSRPPWHVDGLRSARSAGINPDRTWDIATIAVRPGAGRGGLCASALYHGLIRAIYANDIEFVVMIMDSHARQLLTSLGMPTQALPGTKTGEYLGSASSTPLWSHVNRGLDQQRQESPDAYRLIFQGTGLDGISMPSDWVWRRKSVAPADA
>NZ_CP045737.1|WP_153651687.1|560611_561796_-|DUF222-domain-containing-protein
MATSTAPTTEDLSDVVRWQARAEAYAIGRMVDYRDAEVARTALIESSLRRKIERSAIALTIGEATGMSEAQIHLRLSIADRVREKTPQVWAAFVDGLIDFNRVSDISSTIEKLHRDESIARLESRVIGYATSHTGAELQQWLRRFVQRVEADLATERADTERADRRVTVTHGDDSMSWLNAYLPSHQAAAIEARLRKEARKPADLDDDRTVAQREADALVAWCTSSEAAKSGIDANIAVTVSADVLAGATPGFAESTDGAWAVPAPWLADVIATGSTFWHRMVVDPVTDDVLSHEYVGRFAPDTLAVALQFLHGVCQAPGCMVPSERCDLDHRIPHPAGPTTGDNMGPLCRRHHTLKGHGPLHWSTSPPQPPPEPIVIEIHPPATHFVMEYVAA
>NZ_CP045737.1|WP_153651686.1|559676_560492_+|hypothetical-protein
MRRLLGTFVAGLVVCAGCTSGSDEQPSPAPASPPALSLASLDLGWSTAQGKLDAGDPPPAPEGVNPLTYERMAADLASWARVTTVDDSVWHAAKPVDAVSEVLPARAAAALRKQARSAVSPRLAVANVFADDVTVLGTPQVSTAWQVSQADDEDGKPYVVLELQTRAAYEVRLGSDGPVRVIGMLRVHGLSAYADTTDDFGVSGGWQEFGAGDCALALDDQLVPESDLEETRSDLQTFQRVGDADDVEMPDLGDDEQVDADYLQRCRAGQV
>NZ_CP045737.1|WP_153651696.1|572572_573706_-|AI-2E-family-transporter
MAENQRIRDRGVVIDEGFGNLQRWGLRIIVIAAAAYVIGWGIGHVWIVLFPVSMALIVSTVLGPPVAFLRSKGWPSALAAALVVVSFIAALMGVIAVLTPQVAGQAGEIASNATDGLQKVRDWVTGEPLNLSDGQISRAIEAVQEKLQSSATAISSGVFSTLSTATSIIVNIILVLMLTFFFVKDGHKFLPWLNALGGQRTGAHLSEVLGRVWATLGGFIRTQTLVALIDAIIIGGGLWILGSPLAVPLAVITFFGGYIPIVGAFVSGALAVLVTIVTNDFKAALIALVIVVAVQQLEGNVLSPLLQGKNMNLHPAVVLMSVTAGGSMFGITGAFLAVPVAASVAEILRYVNERIDDSVSVLAPKEDARAAEPSRDD
>NZ_CP045737.1|WP_153651697.1|573760_574441_-|uracil-DNA-glycosylase
MNRPLHELMAPDWAEALEPVADQIAAMGQFLREEIAAGRSYLPQGDLVLRAFAEPMADVRVLITGQDPYPTPGHPVGLSFSVAPDVRPLPRSLVNIYAELQADLGIPPAPSGDLTPWSRQGVLLLNRVLTVRPGESASHRRKGWEAITEQAIRALVARDAPLVAILWGRDAQSLRPLLGDVPAIESVHPSPLSASRGFFGSKPFSKANELLVAQGAEPVDWSLADR
>NZ_CP045737.1|WP_153654937.1|574437_575529_-|MFS-transporter
MWVVNIPTIKDRTGVDQADLGLMLLVLGASAWVGMQLAGRAIDRLGSRPVVTTAAVALALTIPGPALATDGLQLVLALAVVGFFNGIVDVSQNAQAVVVERAYGRPIMSAFHALFSLGGLVASILGGTLIALDVDVRASLAAAAVLGVVVALSLRPSLIAAPAVHEDAPPRGRAPWTSRVLLLGLLAFALLLGEGVAYDWSTVHLRDSLGSSETVAAFAYGAFSITMTIVRLFADRVVAAWGPAVYVGRAALVGAAGLLGAALAPNAELAIVAWGVFGIGLAGCVPQFFSAAGNVDESASGTYLARVTSMGYLGLLAGPSVIGLLTHWVPLTTAFAVPIVGCLAAGLLAPRALAPATSEESRR
>NZ_CP045737.1|WP_153651698.1|575652_576873_+|MFS-transporter
MSAIASYRALLRIVGPAYILVAFLGRIPLAMSQLGVLVLVSEATDRYGVGGAAAGILAVANAIGSPIFGALSDRIGQRPVVLVQSLMGAAGLAGIVAVTDSDASRVAIFAMAAITGFAIPQVGPLARVRWRPITKDKGDQRRLVDAAFSYEGAADEASFVLGPATIGVLAIIAEPSGALLAAAALLAIFGSWFAIHPTSALVARRSATGGVTSEPLWTGVFVVLVLAQLCIGMIFGSVQTGTTVLATAEGQAGLAGLIHAVLGIGSVIAGLAITGLPERVLYATRMAVASVGLLILTAPLLLVDSLPALITVIALMGFAVAPYMISNFALAGILVPVRKVSTAMTMLAGATGIGYALGAAVAGRLADEHGHTAAFAVTVAAAGLAVVISLTSNKALRQAVPVDQGY
>NZ_CP045737.1|WP_153651699.1|576992_578102_-|alanine-dehydrogenase
MLVGVPREIKNHEYRVAITPAGVHELVRHGHDVVIEQGAGLGSSITDDEYVAAGAKIMDSPDDVWASAELVLKVKEPIEQEYGRMRAGQTLFTYLHLAASRECTDALLASGTTSIAYETVQLADRSLPLLAPMSEVAGRLAPQVGFQHLMASNGGRGVLPGGVPGVYPADVVVIGAGVSGVNAAEVARGMGARVEILDLDVTKLRQVDARFAGMITTVASNAFAIEKAVQQADLVIGAVLVPGAKAPKLISDDLVATMRPGSVLVDIAIDQGGCFESSRPTTHDDPTFPVHDSIFYCVANMPGAVPHTSTYALTNVTLPYAVALADKGWRRAVTDDAALAGGLSTHEGKLVNGPVGEALGLDATPLAAL
>NZ_CP045737.1|WP_153651700.1|578190_578700_+|winged-helix-turn-helix-transcriptional-regulator
MTAPCEATEVTGVPVAKDVRELDDIDERIVAALRREGRMPNNALADKVGIAASTCLTRLRSLIDRGVIAGFHAEVDPAWLGRPIQAMIAVRLRSDARGAITEFSDRLAGMPEVLNVYFLAGADDFHVHVAARDPEDLRSFVVDHLSSAPEVALTETNLIFEHKRGRLAE
>NZ_CP045737.1|WP_153651701.1|578713_579763_-|GNAT-family-N-acetyltransferase
MVPMTDTTSDSLQDLPTLPGQWRARVPGFSDIDALVELRRLDELQGTGEAHIDPAGIESEVAGQASWTRRQIVAVGEDDVPRAWITVHDRAAGRALVWGYFDRDVPEVDQIAAAFYGWAESAAVSMARLRGVTETRLDESPFAGDHRQAGWLRDAGYAKRRTWLHMERPVATEDAALEPRAGVTVRRVERHENGLPVAADLQVVHQMLEESFEDHFNSYRESFPEFVQRLREDPGHSWDHWWLAYVDPEDGGDPLAAGTLVCSVLTAKEGGAEGTYVEYIGVNRSARGRGVAKSLLGVAIADAAARGRDRVGLEVDADSPTKADQLYLTLGFETDYATDSWFKDIRIED
>NZ_CP045737.1|WP_153651702.1|579790_580375_-|GNAT-family-N-acetyltransferase
MPTFHHAVTLTGRRVRLEPLTPDHAAGVLAAADTDEVFRWLSFERPKDLQAARALVDRYLDDPALVAWAQVDTSTGRVAGLTTYYDVDETLRTVAIGFTWLGSAHWRTGINTEAKLLLLTRAFDDLGCVRVVWHTDIFNERSQQAIARLGAQREGVMRKHRLRRDGTWRDTVLFSMIDEEWPAARAHLTSRLDH
>NZ_CP045737.1|WP_153651703.1|580379_580871_-|ASCH-domain-containing-protein
MTADELDAFWSVARHQTRTNPVPGYLGTFSGEALVPPAWAFGATPEQADELIQLVLDGTKTATASAEWDYVHEDEQLPRVGDLAIVLDGSQHPRALIEVMRVDVVPFETVDAEHAHLEGEGDRSLEHWREVHRRFFTEHASHDRGFDPAMPVVLERFRVLYPR
>NZ_CP045737.1|WP_153651704.1|580901_582326_-|aminotransferase-class-V-fold-PLP-dependent-enzyme
MSTDDLLRRLQQLRAHDLPTHGGRTLAYVYDSGLADTDELGKQALAMYASTNGLDPTAFPSLLAMEKDLVAFARPLFHGTADTVGTVTSGGTESILLAVQAARDARPVAAPVMIVPTTIHAAFAKASHYFGVERVAVDVDPVTRRADPVAMAAAMDAHRDRVVLVAASAPSYAHGVVDPIEAIAAETSARGLRFHVDACIGGWVLPWAERLGHDIGPWDFRVPGVTSLSADLHKYAYTPKGVSLLLHATPDLRRPQFFASADWPGYTMLNATTQSTKSGGPLAAAWAVVHLIGDDGYLDLVRTTLAGTAALVAGVEEQPHVRLVTRPDSSLVTLETDTACDVFTLSDEMLAHGWFVQPQMSFRDMPASLHLTVCAATAPAVPEFLTALAESVDAAVAAGPIVVDEDLREAAVSIDPATLDDAAFDGLLSLAGLGSGTGEVTVPDRMAPVNALLDVAPPALREALLIAFLDRLSR

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP045737_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045737_3

855941-856059

Orphan

Consensus_repeat	Method
GGCGATGAGGGTTACGGGCAGCTGGGGCTACCGCGAACCCTCATC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045737_3

>merge|NZ_CP045737|3|855941-856059|CRISPRCasFinder
GGCGATGAGGGTTACGGGCAGCTGGGGCTACCGCGAACCCTCATCCTGCGTCCCCCCGGCGCGGGCGCGGGACGGGCGATGAGGGTTACGGGCAGCTGGGGCTACCGCAAACCCTCATC

>NZ_CP045737|3|3|855941-856059|CRISPRCasFinder
GGCGATGAGGGTTACGGGCAGCTGGGGCTACCGCGAACCCTCATC	CTGCGTCCCCCCGGCGCGGGCGCGGGACG
GGCGATGAGGGTTACGGGCAGCTGGGGCTACCGCAAACCCTCATC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045737.1\|WP_153651935.1\|864364_864487_-\|50S-ribosomal-protein-L36	unknown	unknown	gnl\|CDD\|179138
NZ_CP045737.1\|WP_153651920.1\|845252_846020_-\|enoyl-CoA-hydratase	unknown	unknown	gnl\|CDD\|180298
NZ_CP045737.1\|WP_153651932.1\|861770_862964_+\|homogentisate-1,2-dioxygenase	unknown	unknown	gnl\|CDD\|226039
NZ_CP045737.1\|WP_153651922.1\|847801_849241_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274522
NZ_CP045737.1\|WP_153651930.1\|859937_860432_-\|AsnC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|214628
NZ_CP045737.1\|WP_153651929.1\|859068_859914_-\|PhzF-family-phenazine-biosynthesis-isomerase	unknown	unknown	gnl\|CDD\|223461
NZ_CP045737.1\|WP_153651921.1\|846016_847678_-\|PucR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|377939
NZ_CP045737.1\|WP_153651931.1\|860553_861753_+\|4-hydroxyphenylpyruvate-dioxygenase	unknown	unknown	gnl\|CDD\|273528
NZ_CP045737.1\|WP_153651928.1\|857757_858996_+\|DUF222-domain-containing-protein	unknown	unknown	gnl\|CDD\|367155
NZ_CP045737.1\|WP_153651926.1\|854478_855915_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_CP045737.1\|WP_153651927.1\|856092_857550_-\|protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP045737.1\|WP_153651919.1\|844264_845227_+\|nitronate-monooxygenase	unknown	unknown	gnl\|CDD\|224981
NZ_CP045737.1\|WP_153651936.1\|864547_864958_-\|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl\|CDD\|181730
NZ_CP045737.1\|WP_153651924.1\|850736_852086_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|366721
NZ_CP045737.1\|WP_153651918.1\|841856_844124_+\|catalase/peroxidase-HPI	unknown	unknown	gnl\|CDD\|237891
NZ_CP045737.1\|WP_153651934.1\|864120_864291_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182059
NZ_CP045737.1\|WP_153651925.1\|852104_853481_+\|aminotransferase-class-III-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|235823
NZ_CP045737.1\|WP_153651933.1\|862936_864118_+\|fumarylacetoacetase	unknown	unknown	gnl\|CDD\|215461
NZ_CP045737.1\|WP_153651923.1\|849302_850733_+\|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|143411
NZ_CP045737.1\|WP_153654965.1\|853790_854369_-\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|188483

Protein	Function_ID	Function_description	E-value
NZ_CP045737.1\|WP_153651935.1\|864364_864487_-\|50S-ribosomal-protein-L36	gnl\|CDD\|179138	PRK00831, rpmJ, 50S ribosomal protein L36; Validated.	1.38026e-10
NZ_CP045737.1\|WP_153651920.1\|845252_846020_-\|enoyl-CoA-hydratase	gnl\|CDD\|180298	PRK05870, PRK05870, enoyl-CoA hydratase; Provisional.	3.09691e-77
NZ_CP045737.1\|WP_153651932.1\|861770_862964_+\|homogentisate-1,2-dioxygenase	gnl\|CDD\|226039	COG3508, HmgA, Homogentisate 1,2-dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism].	4.24192e-64
NZ_CP045737.1\|WP_153651922.1\|847801_849241_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|274522	TIGR03329, Phn_aa_oxid, putative aminophosphonate oxidoreductase. This clade of sequences are members of the pfam01266 family of FAD-dependent oxidoreductases. Characterized proteins within this family include glycerol-3-phosphate dehydrogenase (1.1.99.5), sarcosine oxidase beta subunit (1.5.3.1) and a number of deaminating amino acid oxidases (1.4.-.-). These genes have been consistently observed in a genomic context including genes for the import and catabolism of 2-aminoethylphosphonate (AEP). If the substrate of this oxidoreductase is AEP itself, then it is probably acting in the manner of a deaminating oxidase, resulting in the same product (phosphonoacetaldehyde) as the transaminase PhnW (TIGR02326), but releasing ammonia instead of coupling to pyruvate:alanine. Alternatively, it is reasonable to suppose that the various ABC cassette transporters which are also associated with these loci allow the import of phosphonates closely related to AEP which may not be substrates for PhnW.	1.31213e-52
NZ_CP045737.1\|WP_153651930.1\|859937_860432_-\|AsnC-family-transcriptional-regulator	gnl\|CDD\|214628	smart00344, HTH_ASNC, helix_turn_helix ASNC type. AsnC: an autogenously regulated activator of asparagine synthetase A transcription in Escherichia coli).	1.31338e-23
NZ_CP045737.1\|WP_153651929.1\|859068_859914_-\|PhzF-family-phenazine-biosynthesis-isomerase	gnl\|CDD\|223461	COG0384, COG0384, Predicted epimerase, PhzC/PhzF homolog [General function prediction only].	8.36084e-79
NZ_CP045737.1\|WP_153651921.1\|846016_847678_-\|PucR-family-transcriptional-regulator	gnl\|CDD\|377939	pfam07905, PucR, Purine catabolism regulatory protein-like family. The bacterial proteins found in this family are similar to the purine catabolism regulatory protein expressed by Bacillus subtilis (PucR). PucR is thought to be a transcriptional activator involved in the induction of the purine degradation pathway, and may contain a LysR-like DNA-binding domain. It is similar to LysR-type regulators in that it represses its own expression. The other members of this family are also annotated as being putative regulatory proteins.	1.33298e-34
NZ_CP045737.1\|WP_153651931.1\|860553_861753_+\|4-hydroxyphenylpyruvate-dioxygenase	gnl\|CDD\|273528	TIGR01263, 4-hydroxyphenylpyruvate_dioxygenase, 4-hydroxyphenylpyruvate dioxygenase. This protein oxidizes 4-hydroxyphenylpyruvate, a tyrosine and phenylalanine catabolite, to homogentisate. Homogentisate can undergo a further non-enzymatic oxidation and polymerization into brown pigments that protect some bacterial species from light. A similar process occurs spontaneously in blood and is hemolytic (see . In some bacterial species, this enzyme has been studied as a hemolysin. [Energy metabolism, Amino acids and amines].	4.83391e-160
NZ_CP045737.1\|WP_153651928.1\|857757_858996_+\|DUF222-domain-containing-protein	gnl\|CDD\|367155	pfam02720, DUF222, Domain of unknown function (DUF222). This family is often found associated to the N-terminus of the HNH endonuclease domain pfam01844. The function of this domain is uncertain. This family has been called the 13E12 repeat family.	1.32979e-16
NZ_CP045737.1\|WP_153651926.1\|854478_855915_+\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	2.85608e-46
NZ_CP045737.1\|WP_153651927.1\|856092_857550_-\|protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	8.84338e-101
NZ_CP045737.1\|WP_153651919.1\|844264_845227_+\|nitronate-monooxygenase	gnl\|CDD\|224981	COG2070, COG2070, Dioxygenases related to 2-nitropropane dioxygenase [General function prediction only].	4.47335e-83
NZ_CP045737.1\|WP_153651936.1\|864547_864958_-\|aminoacyl-tRNA-hydrolase	gnl\|CDD\|181730	PRK09256, PRK09256, aminoacyl-tRNA hydrolase.	1.13847e-50
NZ_CP045737.1\|WP_153651924.1\|850736_852086_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|366721	pfam01593, Amino_oxidase, Flavin containing amine oxidoreductase. This family consists of various amine oxidases, including maze polyamine oxidase (PAO) and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.	1.41991e-66
NZ_CP045737.1\|WP_153651918.1\|841856_844124_+\|catalase/peroxidase-HPI	gnl\|CDD\|237891	PRK15061, PRK15061, catalase/peroxidase.	0
NZ_CP045737.1\|WP_153651934.1\|864120_864291_-\|hypothetical-protein	gnl\|CDD\|182059	PRK09752, PRK09752, AIDA-I family autotransporter YfaL.	4.89991e-06
NZ_CP045737.1\|WP_153651925.1\|852104_853481_+\|aminotransferase-class-III-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|235823	PRK06541, PRK06541, aspartate aminotransferase family protein.	0
NZ_CP045737.1\|WP_153651933.1\|862936_864118_+\|fumarylacetoacetase	gnl\|CDD\|215461	PLN02856, PLN02856, fumarylacetoacetase.	6.03176e-147
NZ_CP045737.1\|WP_153651923.1\|849302_850733_+\|aldehyde-dehydrogenase-family-protein	gnl\|CDD\|143411	cd07092, ALDH_ABALDH-YdcW, Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like. NAD+-dependent, tetrameric, gamma-aminobutyraldehyde dehydrogenase (ABALDH), YdcW of Escherichia coli K12, catalyzes the oxidation of gamma-aminobutyraldehyde to gamma-aminobutyric acid. ABALDH can also oxidize n-alkyl medium-chain aldehydes, but with a lower catalytic efficiency.	0
NZ_CP045737.1\|WP_153654965.1\|853790_854369_-\|TetR-family-transcriptional-regulator	gnl\|CDD\|188483	TIGR03968, transcriptional_regulator_TetR_family, mycofactocin system transcriptional regulator. Members of this family are TetR family putative transcriptional regulators that occur in genome contexts near proteins of the mycofactocin system. These include the precursor peptide (TIGR03969), a radical SAM peptide maturase (TIGR03962), and a putative carrier protein (TIGR03967). [Regulatory functions, DNA interactions].	1.17602e-25

>NZ_CP045737.1|WP_153651926.1|854478_855915_+|MFS-transporter
MTDQDVAAPQPPVRASSRRATLELVFVGLGALVVALSQSLLIPVLSILPAELDTSAGNVNWLLTSTLLAAAVSVPIMGRLGDMFGKRRLLLVAVGALVVGSLLTAVTDNIGLLIAGRAIQGCAAAAIPLGISLLAAVLPREKVGSAIALVSAMLGIGGALGLPIAGLVAENADFHVLFWITFGAGLIAFVGILAIVPEAPGRSGGRVDLVGSVLLAAGLICLLLPLSQSSAWGWGDSRIWILLAIAAVLIAVFGFSQMRIKDPLVDLRALGRRPIVLTNLASILFGFALFASFIGTASYVEAPESTGYGFGSSLLVGGLAMLPGGIAMLLLSPVAARLIERRGAPQTLALGAVIVAAGFLMRIVVHDSLWQVIVGSAIVGAGTGVGYAAMPALINAHTPGNEIAAANGLNSLFRSLGSSLASAIGGSILAANTVILGDIAAPSLSAYQQLFAICGGAAVVAAVLVLLIPHRPTSPGSH
>NZ_CP045737.1|WP_153654965.1|853790_854369_-|TetR-family-transcriptional-regulator
MSLRDHARGAVRDEIARKAWRLLADQGFEATTIDQIAEAAGMSRRTFFRYFASKDELVLTRLVESGDRIAEALRARPADEPAWPALRAAFQHIVELQEAHAEVARPLQVMLRAEPALRATRQERRTLWLELLAPLVAERLPPRPGRTGPDIRALALTGSALACFEAAQGAWAENPGVPLASLLDEAMESVGG
>NZ_CP045737.1|WP_153651925.1|852104_853481_+|aminotransferase-class-III-fold-pyridoxal-phosphate-dependent-enzyme
MDVPNPEHDRLQQSAKDHLVLHFSKQEIDDLLVLDRGEGPYVFDTKGRRYIDALSSLFCSQLGYSYGEEMADAARRQLTSLAFNTSWGTSHPAAIDLAEKIADLAPADDYRVFFTGGGSESVEAAWKMVREHFIAIGQPQRTKAIARDRAYHGVTLGALSFTGVRPFKEGFGEPPVPVTHVSNTNTFRAPDGADEAAFCARLLAEVEEAIVAAGADEVALIIAEPVQNAGGCFTAPAGYWPGLRRLADQYGVLLMADEVITGFGRIGEWFASSREGVAPDLVTVAKGLTSAYAPMGATLVRERVIAPLVEQRKVFRHGITFGGHPLSAALAMKSIEIIERDQVLENVRAQADPLRERLNHLLDLPIVGDVRGAGFFWAMELVKDDAATRFDQAERDDLLRGFLPARLREAGLIARCDDRGDSVLQIAPPLISDAALLDDIAAGLTDVLRDAGKHMSLS
>NZ_CP045737.1|WP_153651924.1|850736_852086_+|FAD-dependent-oxidoreductase
MADKQVDVLVVGAGATGLSAAYALQRAGRSVLVLESRDRVGGRLWTDEVDGVDLEIGGQWVSPDQEALLAMLDELGLETFERHREGESVYVGLDGERRTFTGEVLPVAPAVEAEMNRLTERLDELSAQMDPARPWDMAGAAELDHVTFRAWLDAQCEHEEARDNIAMFIAQAMLTKPVHTFSALQAVHMAASAGSFSNLVDSEFILDRRVIGGLQQVPLQLAARLGDVVCTAHDVEKVRWHDGGVTVTSGDLTVSARHLVLAIPPTAVTRVRFEPPLPSIQRETRQHQSFGQVIKVHATYETPFWRDAGLSGTAFSPYLTVHEAYDNTNHDEERGTLVGFVSDVQADAVLALDPDQRRGIILESLQTYFGPGAGTPLTYFESDWTSEELGSGAYGASFDLGGMTRFGPRLREPAGPIQIGSSDVAGLGFQHVDGALRVGAELAQHIIDS
>NZ_CP045737.1|WP_153651923.1|849302_850733_+|aldehyde-dehydrogenase-family-protein
MSDIVRNYVNGAPVDSAATDFIELVDPTTGLADGRSPISTAAEVDEAFAAALAASRTWKRTTPKVRQLALLQIADAVEAARDELVALQARDTGQVKEHIATEEIDQGVDQLRFFAGAARLLEGKATAEYVEGLSSSIRREPIGVVAQVTPWNYPFAMAIWKIAPALAAGNTIVLKPSDTTPRSTVRLAEIAGEILPPGVLNVVNGNADTGRLLVEHPVPGLVAITGSVRAGIEVAVSAARNLKRAHLELGGKAPAVVFADADLAAAAEGIAVGGFFNAGQDCTAATRVIVHESVHEELLRLLVEQARAARPGAPDDAEATYGALNNAGHLASVERMVGAIGDHARIETGGRRLDRDGFYFEPTVISGVRQDDAIVQQEVFGPVLTVQPFATTQQATELANDVPYGLAASVWTKDHGRALRMTADLDFGCVWVNTHIPFVSEMPHGGFGASGHGKDLSAYGLEEYTRVKHVMSNVEG
>NZ_CP045737.1|WP_153651922.1|847801_849241_+|FAD-dependent-oxidoreductase
MASHRTVFERQRPPEAQVTESLRDSRHAVFWLEDVETVNRPALSGTIDADLTVVGGGYCGLWTAVLAKRRDPTARVVLLEAETIGWAASGRNGGFAEASLTHGEDNGRARWAAEYDTLHRMGLDNLDAIERDVEELKMDVQLERTGVLEVAYEPHQVRWLQEAGHGQWLDRDAVRAEIASPIFEAGRWVKDTCALVHPGRLAQELARVATDLGVEIFEHSAVSGLGTGLGSGLGSGRSGAVDVRTTRGLVRSRRVALATNVFRPLLRRSRLLTVPVYDYVLMTEPLSPGQMAEIGWQHRQGVSDLANQFHYSRLTADNRILYGGYDAIYHAGRGVRPEHEDRDASYRRLASHLLTTYPQLEGLRFSHRWAGAIDTSTQFCAFHGLARRGRVAYAAGFTGLGVAATRFAAEVMLDRLAGETTARTQLEMVRKKPLPFPPEPFTKIGIEATKWSLDRADHREGRRNLMLRTLDRLGLGFDS
>NZ_CP045737.1|WP_153651921.1|846016_847678_-|PucR-family-transcriptional-regulator
MPLTLRTILAMDVLTAGRPEVLAGEQSLDRPVRWVHVTEVDDMVDLLGGHEVVLTTGLPLVGPTADPERFVTQLAEASACGLIVELGPRLPELPAALVRQARRLELPLVALHAPVRFVSITEAVHRLIVGEQYHGLELAQRTHEVFTNLSLDSADASTILAEASTLIGAPVVLEDVGHHVVALARHGRTSGALLRGWEERSRRAPVLDEAGTSGPERWLTCPVGLRGAPWGRIVAPQQTHDPVTTAMVMQRAAQALQLSRLVERDATRLQSQAQESLLQELVEGRVQDEADGLARAAALGMRAGASYLPVVALFGPAALPDQIARQRRARAQLETVSDALAEARLDAISGGVDDQGVGIVLALPRGVTEDAALEALATATASRAGALTPGTVPVLGVGRAAGTLLVAASRMPATVHVAEAARALQPSSAAWFRSTDVRLRGLVAQLRDDERVLGFAEAELGPLLAHEAEHGTGLLDLLRRYVELRGNKAALAQATHISRQALYGRLHKLESILRVDLDDADSVLSLGVALLVHDLRVGRARPGPGRRGTTVTS
>NZ_CP045737.1|WP_153651920.1|845252_846020_-|enoyl-CoA-hydratase
MTSRPTTLSIHGATALLTLDDPDRRNILTSEMVCSIDEDVTRAEATPEVNTLVVTGRGRAFCAGAELATLEQSAAGDFDDVREVYEGFLRILRTPLATIAAVNGPAVGAGLNLALACDVRIASTAARFDTRFAHLRIHPGGGHTWLMERAVGHQQATLAVLFGERWDAERAYDVGLVARVVEPESLVDEALALGARLDDMEGDLVRRYVSTLRQAQQTPDHETIFDVETTAQAWSTTRPAFVQNVRALRESISGR
>NZ_CP045737.1|WP_153651919.1|844264_845227_+|nitronate-monooxygenase
MTLVPALAGPLTLPVVGSPLFICSGPELVGAQCRAGIIGAFPALNARPAALLSDWIQQIDEENASFAAADPDAYVGPFAVNQIVHRSNDRLEQDMAVIVEHQVPIVITSLGARTEINDAVHSYGGIVLHDVIDDEFARKAIDKGADGVIAVAAGAGGHAGTQSPFALVREIRSWFDGPLLLSGAISHGSSILAAQAAGADLAYVGSAFLATHEANAAPDYKQMIVDSTAKDIVYSNLFTGVHGNYLRGSIEAAGMDPDDLGVSDPSAMDFSSQAVDGPKAWRDIWGAGQGIGAIEERVSVAALVQSLRAQYDQARKDLCG
>NZ_CP045737.1|WP_153651918.1|841856_844124_+|catalase/peroxidase-HPI
MNDSQTPESPQGIDRKAEAGCPVMPDSAAAHGSESENPAIDSPTPKTGGRPRTNKDWWPNQVDLSVLHAHSSKANPLGPDFVYAEEFKKLDLAELRRDIVEVLNTSQDWWPADFGHYGGLFIRMSWHAAGTYRIFDGRGGAGEGNQRFAPLNSWPDNANLDKARRLLWPVKQKHGQKISWADLLVYAGTVAMEDMGFTTFGFGFGREDVWEPEEIIWGPEDTWLGDERYSGDRELEEALGSVQMGLIYVNPEGPNGNPDPLASARDIRATFARMAMNDEETVALIAGGHTFGKTHGAGDADLVGPEPEAAPLEEQGLGWRSEYGTGKGEDAITSGLEVTWTSTPTRWSNDFFKFLFKYDWELTKSPAGAYQWVAKDAEDIVPGPAADSPKRKPTMLTSDLALRFDPEYEKISRRFLENPNEFSVAFAKAWYKLLHRDMGPIDRYLGPWVPEPQLWQDPVPAPEGELVGDADVASLKAKVLESGLSVSELIATAWASAATFRSTDKRGGANGARIRLEPQRSWEVNQPEQLANVLAKLEGIQAEFNSAGGAQISMADLIVLAGNAAVEKAAKDAGVEITVPFHPGRGDATQEQTDVHSFKVLEPRADGFRNYLRAADKFSPETQLVERAYMLDLTAPEMTVLVGGMRALGGNVDGAKHGVLTDRPGVLTNDFFVNLLAPGARWKASESQENVFEIRDAATDELKWTATAVDLVFGSNSQLRALSEVYASDDAREKFVADFVAAWTKVMELDRFDLK
>NZ_CP045737.1|WP_153651927.1|856092_857550_-|protein-kinase
MLADRYELDHEIGRGGMGTVWLARDVVLHRVVAVKQIGMGPGGGEPDLQRAEREAHLAARINHQNVVAVFDLVDEGGHQWLVMEHVDGPSLAGLIAERGALDPAEVAPIVEQVAAALAAAHEHGIVHRDVKPSNILLTHDGVAKLSDFGVARAQADASLTQTGLVTGSPAYLSPEVASGRTATAASDVWSLGATVFHALAGGPPYEVGDNLLGTMYRIVNEAPPTLEAGGPLAALVAAMMQHDPDARPTMAAVEEAVSTQSGVELDLESTQAMPAATAVARPTATTAFRPLEPPVEPAVPPVAPAVAAKPTPAATAPGRRASPTRSRTPWLITAGAVAALIAVVSFVGLRGGSADDAPRAAGERSSAGSGSASTEDEPAPAGDGEVTAEQMEGFAADYLSTASNDPDAGFTMLTPGYQRASNGIEGYKGFWEDVADLSVERVSADPASLRVSYTYSYDFKGDRRTEAVTLQLEKSGDSFLIAGAT
>NZ_CP045737.1|WP_153651928.1|857757_858996_+|DUF222-domain-containing-protein
MNPKPTIDAMRTAAQALSSGDVRETLHAVQMAQDALDAVKGVLLAELQASKDFELDGASTLNTWVRNQLHLKSGQATVLVKSVAALRDLPLVAEAATSGLISAAHVQVFVYGLAHVGLEPMLQHEEVLVAVAAENEPGVLWEAVKHLKAITHPEDLDEAWKGGMDKEDFAVDALPDGFHVTGFLNTLTGLKLKKVMDSVSAPRDADDTRTGAQRRVQGLDDLLDSILGNGLPSDKGVRPHMSVFVDAETLEAAAERVEQETEHPHLIPDPMPESEPATLAGHGAIGPHLLMFLFCLSGVTGFVREQDQILNVGHTRYEPNMKQRKAVLARQRGVCATPGCNHTHLEVHHSVWWSLGGRTDLDQLVGLCVRCHHLVHRGLLHVAGNAVDGFEFTNRHQRPVRRRRRTGYRRAA
>NZ_CP045737.1|WP_153651929.1|859068_859914_-|PhzF-family-phenazine-biosynthesis-isomerase
MHPFSQVDVFASELTLGNPVAVVHDADDLDEAQMAAFARWTNLSETTFLLRPTTPQADYRVRIFTTARELPFAGHPTLGTARAWLEAGGEPAHAGELVQQCAAGLVRVRMDGDRLAFAAPPLVRSGPVDAADLDEATAALGLDPSQVIDAAWVDNGPGWAALLLDSAETVLALEPDPSAFGVLDKVGVVGPHSPGGETAFEVRAFVPGSIGEDPVTGSLNASIGQWLTSTGRAPASYVAAQGTRLGRRGRVHVDLVDDVLWVGGRTTVGISGSVTAWGAGA
>NZ_CP045737.1|WP_153651930.1|859937_860432_-|AsnC-family-transcriptional-regulator
MDQLDVALVEAMHAHPRVGDLELSRLTHVARATVQSRLAKLEEAGVITGYGPSVDLVAAGHPVLAFVTLEIMQGSLDAVTAELDSLPNVLEAYITSGNADVVCKIAATSHEDLKDTLLHISQSGSVARSTSVIVLSELVPPRVLPMLRKGADDGPSRSPSFRSA
>NZ_CP045737.1|WP_153651931.1|860553_861753_+|4-hydroxyphenylpyruvate-dioxygenase
MTLDLTDAERLADLDLAQLQQLVGLVEHDPTTDPFPVTGWDAVVWAVGNATQSAHFYMSAFGMDLVAYSGPETGNRDHHAYVLESGAVRFVLRGGVAPDSPVADHHRLHGDGITDIALEVPDVDVCIDHARAEGATILEEPHDVSDEHGTVRVAAIAAYGDTRHTLVDRSRYDGPYLPGYVARSSSLVRADDAPKRIFQALDHVVGNVEIGHMDEWVDFYNRIMGFTNMAEFVGDDIATEYSALMSKVVASGNHRVKFPLNEPAVGKKKSQIDEYLEFYQGPGAQHLALATNDILETVDRLRAAGIEFLATPDSYYTDPALRERIGEVRVPIEELQSRGILVDRDEDGYLLQIFTKPIGDRPTVFFELIERHGSLGFGKGNFQALFEAIEREQARRGNF
>NZ_CP045737.1|WP_153651932.1|861770_862964_+|homogentisate-1,2-dioxygenase
MAHYRSAGHVPPKRHTQHRAPNGALYREELMGEEGFSSDSSLLYHRGVPSAIVDARRWELPDHTTTPNEPLLARHLKLHDLFDGGAGRDLVTGRRLVLANADVRISYAVGAETSPLYRNATGDECVFVEDGSGTLETVFGHIAFGPGDYLLVPRATTHRWVPAGDVRAYCIEANSHIAPPKRYLSRYGQLLEHAPYCERDLRVPGEPEIREDIDVEVLIKHRGSGPLGLAGSVHVVPQHPFDVVGWDGCLYPYAFNVADFEPITGRVHQPPPVHQVFEGANFVICNFVPRKVDYHPLAIPVPYYHSNVDSDEVMFYVAGDYEARKGSGIGRGSVSLHPGGHSHGPQPSAIEASLGAESFDELAVMVDTFRPLELGEAGRACDDGRYAWSWSGSGARG
>NZ_CP045737.1|WP_153651933.1|862936_864118_+|fumarylacetoacetase
MVGVRGARVTDFGRTTLPYCSFVRPGEARARVGVGVGTDVVDLTAALATRRHAYAGLFAAGSLDPLLAAGPRTWHEVRTYVAANLSALAEHQVPASGVELVLPFEVADYVDFYASEHHASNVGRLFRPDGDALTPNWKHLPIGYHGRAGTVVVSGTPIRRPSGQMRERDGTIAFGPTAKLDLEAETGFVVGAGSSLGEPVPVESFDQHVFGVCVVNDWSARDVQAWEYVPLGPFLGKSFATSVSPWVVPLAALAGARIDPPRRDPDPVAYLQDDEPWGLDLELEIAVNGTVVSRAPYSEMYWTPAQMLAHLTVNGAALRPGDLFASGTVSGPGPGQQGSLLELSWNGSRPVTLDDGSTRAFLLDGDRVTIAATARLAGGRRIALGQVEGQVTS
>NZ_CP045737.1|WP_153651934.1|864120_864291_-|hypothetical-protein
MTVAPPEPALPEEDQPSRPETPDLPDPAFPEVLPTPEPGEEPDREPAPETQPDREG
>NZ_CP045737.1|WP_153651935.1|864364_864487_-|50S-ribosomal-protein-L36
MKVRSSLRSLKNQPGSQVVRRHGRTFVINRDNPRLKARQG
>NZ_CP045737.1|WP_153651936.1|864547_864958_-|aminoacyl-tRNA-hydrolase
MSHDRRLSLPESEMTWRFSRSSGAGGQHVNTTDTRVELIWSLADTAALSPAQKELAATRLGNRLVDGVITIVSSQYRSQHRNREDARVRLEELVGQAIVPDRPRRPTRPSRSSQRRRLDAKKRRGSLKEGRSGTWE

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP045737_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045737_4

1201870-1201968

Orphan

Consensus_repeat	Method
CCCAGCAGCGCGAACGCCGAAAGATCCGTGCGGCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045737_4

>merge|NZ_CP045737|4|1201870-1201968|CRISPRCasFinder
CCCAGCAGCGCGAACGCCGAAAGATCCGTGCGGCGTACGACCGAAGTCTCGGCGTTGACGTCGCCCCAGCAGCGCGAACGTCGAAAGATCCGTGCGGCG

>NZ_CP045737|4|4|1201870-1201968|CRISPRCasFinder
CCCAGCAGCGCGAACGCCGAAAGATCCGTGCGGCG	TACGACCGAAGTCTCGGCGTTGACGTCGC
CCCAGCAGCGCGAACGTCGAAAGATCCGTGCGGCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045737.1\|WP_153652222.1\|1199586_1200153_+\|16S-rRNA-(guanine(966)-N(2))-methyltransferase-RsmD	unknown	unknown	gnl\|CDD\|223813
NZ_CP045737.1\|WP_153652224.1\|1200703_1201585_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|236600
NZ_CP045737.1\|WP_153652227.1\|1203166_1203880_+\|DUF177-domain-containing-protein	unknown	unknown	gnl\|CDD\|376863
NZ_CP045737.1\|WP_153652231.1\|1207414_1209304_+\|DNA-primase	unknown	unknown	gnl\|CDD\|235551
NZ_CP045737.1\|WP_153652219.1\|1193083_1194040_+\|thiamine-phosphate-kinase	unknown	unknown	gnl\|CDD\|235583
NZ_CP045737.1\|WP_153652225.1\|1201581_1201818_+\|DUF1059-domain-containing-protein	unknown	unknown	unknown
NZ_CP045737.1\|WP_153652232.1\|1209379_1209973_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274107
NZ_CP045737.1\|WP_153652223.1\|1200149_1200623_+\|pantetheine-phosphate-adenylyltransferase	unknown	unknown	gnl\|CDD\|234674
NZ_CP045737.1\|WP_153652226.1\|1201975_1203160_-\|DNA-polymerase-IV	unknown	unknown	gnl\|CDD\|179663
NZ_CP045737.1\|WP_153652218.1\|1192760_1192997_-\|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|366431
NZ_CP045737.1\|WP_056607529.1\|1203883_1204069_+\|50S-ribosomal-protein-L32	unknown	unknown	gnl\|CDD\|237038
NZ_CP045737.1\|WP_108577479.1\|1195525_1195711_-\|50S-ribosomal-protein-L28	unknown	unknown	gnl\|CDD\|234736
NZ_CP045737.1\|WP_153652228.1\|1204783_1205650_+\|bifunctional-DNA-formamidopyrimidine-glycosylase/DNA-(apurinic-or-apyrimidinic-site)-lyase	unknown	unknown	gnl\|CDD\|234899
NZ_CP045737.1\|WP_153652233.1\|1210286_1210952_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045737.1\|WP_153654989.1\|1204065_1204779_+\|ribonuclease-III	unknown	unknown	gnl\|CDD\|234633
NZ_CP045737.1\|WP_153652221.1\|1197454_1199590_+\|ATP-dependent-DNA-helicase-RecG	unknown	unknown	gnl\|CDD\|236794
NZ_CP045737.1\|WP_153654988.1\|1194041_1195451_-\|amidase	unknown	unknown	gnl\|CDD\|181154
NZ_CP045737.1\|WP_153652220.1\|1195868_1197455_+\|DAK2-domain-containing-protein	unknown	unknown	gnl\|CDD\|274671
NZ_CP045737.1\|WP_153652229.1\|1205663_1206134_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP045737.1\|WP_153652230.1\|1206130_1207363_+\|deoxyguanosinetriphosphate-triphosphohydrolase	unknown	unknown	gnl\|CDD\|235098

Protein	Function_ID	Function_description	E-value
NZ_CP045737.1\|WP_153652222.1\|1199586_1200153_+\|16S-rRNA-(guanine(966)-N(2))-methyltransferase-RsmD	gnl\|CDD\|223813	COG0742, COG0742, N6-adenine-specific methylase [DNA replication, recombination, and repair].	2.2615e-53
NZ_CP045737.1\|WP_153652224.1\|1200703_1201585_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|236600	PRK09636, PRK09636, RNA polymerase sigma factor SigJ; Provisional.	3.02137e-57
NZ_CP045737.1\|WP_153652231.1\|1207414_1209304_+\|DNA-primase	gnl\|CDD\|235551	PRK05667, dnaG, DNA primase; Validated.	0
NZ_CP045737.1\|WP_153652219.1\|1193083_1194040_+\|thiamine-phosphate-kinase	gnl\|CDD\|235583	PRK05731, PRK05731, thiamine monophosphate kinase; Provisional.	8.33471e-111
NZ_CP045737.1\|WP_153652227.1\|1203166_1203880_+\|DUF177-domain-containing-protein	gnl\|CDD\|376863	pfam02620, DUF177, Uncharacterized ACR, COG1399. This family is nearly universally conserved in bacteria and plants except the Chlorophyceae algae. Thus far, mutantional analysis in bacteria have not established a function. In contrast, mutants have embryo lethal phenotypes in maize and Arabidopsis. In maize, the mutant embryos arrest at an early transition stage.It has been suggested that family members specifically affect 23S rRNA accumulation in plastids as well as bacteria.	1.34276e-28
NZ_CP045737.1\|WP_153652232.1\|1209379_1209973_+\|hypothetical-protein	gnl\|CDD\|274107	TIGR02392, RNA_polymerase_sigma_factor_RpoH, alternative sigma factor RpoH. A sigma factor is a DNA-binding protein protein that binds to the DNA-directed RNA polymerase core to produce the holoenzyme capable of initiating transcription at specific sites. Different sigma factors act in vegetative growth, heat shock, extracytoplasmic functions (ECF), etc. This model represents the clade of sigma factors called RpoH and further restricted to the Proteobacteria. This protein may be called sigma-32, sigma factor H, heat shock sigma factor, and alternative sigma factor RpoH. Note that in some species the single locus rpoH may be replaced by two or more differentially regulated stress response sigma factors. [Cellular processes, Adaptations to atypical conditions, Transcription, Transcription factors].	1.67294e-21
NZ_CP045737.1\|WP_153652223.1\|1200149_1200623_+\|pantetheine-phosphate-adenylyltransferase	gnl\|CDD\|234674	PRK00168, coaD, phosphopantetheine adenylyltransferase; Provisional.	1.68763e-96
NZ_CP045737.1\|WP_153652226.1\|1201975_1203160_-\|DNA-polymerase-IV	gnl\|CDD\|179663	PRK03858, PRK03858, DNA polymerase IV; Validated.	0
NZ_CP045737.1\|WP_153652218.1\|1192760_1192997_-\|Lrp/AsnC-family-transcriptional-regulator	gnl\|CDD\|366431	pfam01037, AsnC_trans_reg, Lrp/AsnC ligand binding domain. The l-leucine-responsive regulatory protein (Lrp/AsnC) family is a family of similar bacterial transcription regulatory proteins. The family is named after two E. coli proteins involved in regulating amino acid metabolism. This entry corresponds to the usually C-terminal regulatory ligand binding domain. Structurally this domain has a dimeric alpha/beta barrel fold.	2.1185e-10
NZ_CP045737.1\|WP_056607529.1\|1203883_1204069_+\|50S-ribosomal-protein-L32	gnl\|CDD\|237038	PRK12286, rpmF, 50S ribosomal protein L32; Reviewed.	1.80187e-17
NZ_CP045737.1\|WP_108577479.1\|1195525_1195711_-\|50S-ribosomal-protein-L28	gnl\|CDD\|234736	PRK00359, rpmB, 50S ribosomal protein L28; Reviewed.	3.89208e-25
NZ_CP045737.1\|WP_153652228.1\|1204783_1205650_+\|bifunctional-DNA-formamidopyrimidine-glycosylase/DNA-(apurinic-or-apyrimidinic-site)-lyase	gnl\|CDD\|234899	PRK01103, PRK01103, bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase.	2.98263e-139
NZ_CP045737.1\|WP_153654989.1\|1204065_1204779_+\|ribonuclease-III	gnl\|CDD\|234633	PRK00102, rnc, ribonuclease III; Reviewed.	3.62814e-109
NZ_CP045737.1\|WP_153652221.1\|1197454_1199590_+\|ATP-dependent-DNA-helicase-RecG	gnl\|CDD\|236794	PRK10917, PRK10917, ATP-dependent DNA helicase RecG; Provisional.	0
NZ_CP045737.1\|WP_153654988.1\|1194041_1195451_-\|amidase	gnl\|CDD\|181154	PRK07869, PRK07869, amidase; Provisional.	0
NZ_CP045737.1\|WP_153652220.1\|1195868_1197455_+\|DAK2-domain-containing-protein	gnl\|CDD\|274671	TIGR03599, YloV, DAK2 domain fusion protein YloV. This model describes a protein family that contains an N-terminal DAK2 domain (pfam02734), so named because of similarity to the dihydroxyacetone kinase family family. The GTP-binding protein CgtA (a member of the obg family) is a bacterial GTPase associated with ribosome biogenesis, and it has a characteristic extension (TIGR03595) in certain lineages. This protein family described here was found, by the method of partial phylognetic profiling, to have a phylogenetic distribution strongly correlated to that of TIGR03595. This correlation implies some form of functional coupling.	3.77901e-140
NZ_CP045737.1\|WP_153652229.1\|1205663_1206134_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.54939e-18
NZ_CP045737.1\|WP_153652230.1\|1206130_1207363_+\|deoxyguanosinetriphosphate-triphosphohydrolase	gnl\|CDD\|235098	PRK03007, PRK03007, deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional.	0

>NZ_CP045737.1|WP_153652225.1|1201581_1201818_+|DUF1059-domain-containing-protein
MKTMTCRQLGGPCDLQHRGETADDVINAQDQHLKEAEKAGDATHQEARDAMKSRWRHPKKSLGWYNDAKKAFAALPES
>NZ_CP045737.1|WP_153652224.1|1200703_1201585_+|sigma-70-family-RNA-polymerase-sigma-factor
MDPTHAFELERPRLLSIAARVLGDPVEAEDVVQQAWLRLDAAEADIASAPAWLTTVTTRLCLDRLRARVPVPTEQTAAVVETAPDPADDVALADSVGIALHVVLERLSPAERVAFVLHDSFGFEFATIAVMLETTPAAARKLASRARAKVRQPASEGGPADWEVVDAFMAAAREGDFERLLAILAPDAQVTADAAAVGQGTPELIRGRQQVAEFFNGSAHAALPVFVGDRPGAAWFNRGEAKVLFDFDVVDGLVRGIVFRADADVLARVTRRDRSERRGPADASTSEREGDRR
>NZ_CP045737.1|WP_153652223.1|1200149_1200623_+|pantetheine-phosphate-adenylyltransferase
MTKVVCPGSFDPVTNGHLDIVERSAHLFDEVVVAVLVNENKRGLFSIDERLELLTEATKHLPNVTTASFTGLLVDFCTTNGVDAIVKGLRAVTDFDYELQMAQMNGSLTDVDTVFIPTSPEYSFLASSLVKEVAKHGGDVSGLVPGFVNDELKAKYA
>NZ_CP045737.1|WP_153652222.1|1199586_1200153_+|16S-rRNA-(guanine(966)-N(2))-methyltransferase-RsmD
MTRIIAGRHGGRQIKTPKGDGTRPTSDRVREAMFSSIESELGGLEGIAVLDLYAGSGALGIEAISRGAGHAVFVEAHTQTAAVITRNLRDLGADGVVERTKAERWVEDGDRDVFDLVLIDPPYAVPTDAVTALVQGVLESFSHEDTLFVVERATRDPFVWPEGVEGLRNKKYGETTVWFGRPAVRSLP
>NZ_CP045737.1|WP_153652221.1|1197454_1199590_+|ATP-dependent-DNA-helicase-RecG
MVDLTTKLVNVLGDKTATPLAKAFDMHVVGDLLRHYPRRYVELGKPTNMSDLRVGQHATVLARVVEAKNYSFGPGGKRTRTEVIVTDDSGARLSLTFFQQRWLQDRMKPGKMCLFSGEVGQFNGRLQLTHPDYDLFDEDGDTAASRLSRGVLPIYRATAKIPTWKLESFIALCLDSLDEVDDPLPEQVRTAHGFAGTRAALESIHRPHTMGEAVTARARFRFEEAFIVQTVFAQRRHALEDDRAAARPAVDGGLRTRFEQQLPFTLTAGQRAVVEEVGADLARTHPMHRLLQGEVGSGKTVVALMAMLQVVDAGGQAALLAPTEVLASQHFRGITALLGDLAKGGMLGGADGATRVRLLTGSMGAKARNEALLDAASGEAGIVIGTHALIQDHVQFAELGLLVVDEQHRFGVEQRAALVDRSDVTPHVLVMTATPIPRTIAMSVFGDLEVSTLRELPAGRQPIQTNVVPYAERPGWLARAWERVREEVGKGRQAYVVVSRIGDEPSESDTSSLVELHEELVHGPLHGLRVGTLHGRMSADDKDAAMNAFAAGTIDVLVATTVVEVGVDVPNATVMVVMDADRFGVSQLHQLRGRVGRGSEAGLCLLVTGAEIDSPARERLDAVASTTDGFELSKLDVELRREGDVLGARQSGVRSSLRLLSVVKDEAVIEQARAAADEIVLADPTLSHHPTLAAAVHELEHSEQADYLERT
>NZ_CP045737.1|WP_153652220.1|1195868_1197455_+|DAK2-domain-containing-protein
MGLTLSAAGFRAWTQLCAGALSSARAEIDALNVFPVPDGDTGTNAYLTFMSGADAVEALGPEASFEQLVKTYVDGLLTGAKGNTGVILSQLVRACFRDLSLVGPVEAADVARAFVAASDAAWAAVGAPVEGTILSVAKAAAVGAEDAAEAGVDGRTVFGKAATAAREALARTPSQMEVLARAGVVDAGGRALVVVLDATEQALTGRIPEQVRAHVPQPIRDADDLLSADGPSYEVMYLLEADDDRIPGLRTDLMALGDSLVVVGGERLWNVHVHVDDVGAAIEAGIAAGRPYRIAVTHFADQVARGPQKGRVVITATTGAGLTALCEEAGARTLEFTRDTPLTVAEMSASLRDVGADEIIVLPNNFRYIRQFEAAAQAARQDGVRVAVIPTNAQVQGLAALAVHDPGLGFDEVVVAMSSAAAHTQHGAVTVATEHGITMAGPVGPGDVLGVVTGDFTVIGDDVLEVAYEVIDKILSPAGEMVTVVLGEGSDPSYEASLRAYLRTIRPDVDLLVYDGGQENYPLFIAVE
>NZ_CP045737.1|WP_108577479.1|1195525_1195711_-|50S-ribosomal-protein-L28
MAAVCDVCAKGPGFGHNVSHSHRRTKRRFDPNIQRVRAVINGTPQRVNVCTSCLKAGKVSR
>NZ_CP045737.1|WP_153654988.1|1194041_1195451_-|amidase
MTPRVHAFGDDALGDLDSVGVAAAVAAGDISAREAAEAAIARAERVNPLLNAIQRPDYERALAALAAEPAGALAGVPTFVKDNTDVAGLPSDQGSLAVRARPAPAHAPFTEQLLSTGLTVLGKSTMPEFGFNATTEYATLPPTRNPWHTGYSAGASSGGSAALVASGVVPIAHANDGGGSIRIPAAACGLVGLKPTRDRVAAAAEAASLPIDIISNGVLTRTVRDTAHFLAATQAYRPAPDLRPLGLVEGPSDRRLRIGLILDSVTGIPTDEDTRKAVLATADLLGSLGHDVMEVGLPVDHRFMEDFKHYWALLAFSTQHFGRQVMGPDFDKTLTDPLTRGLARRFVRQAWRTPMAITGLKRSTRAYRAAFDDVDLIVSPTLGYTTPELGYLSPAVEPFSLMFHRLVQYAAFTPLNNASGGPAISLPLGRSSADMPVGIHFSADHGDEQTLLEIAYELEAAQPFARIQD
>NZ_CP045737.1|WP_153652219.1|1193083_1194040_+|thiamine-phosphate-kinase
MNASATNDPTIGDIGEFGLIDRLRERIGHNRHVLLGPGDDAAHVSTQDGTFLVSSDLLIEGRHFRRDWSSPRDIGRKAAACNLSDISAMGGVATALTVGFGAPADLPVSWALEMVRGFEDECAHVGAHIVGGDVTESDKIIIAVTAMGDAARPVRRSGALPGDYVAYSGQLGLAGAGFATLSRGFRSPKAAVEAHRVPSPPYAAGPQAAGVGATSMTDVSDGLLADLGHIADASGVAIDLDSHLIVVPEPVATVSEALGRNAMDFMLTGGDDYALVATFSSETTVPAGWTRIGQVADGSGVTVDGAPYEGASGHQHFR
>NZ_CP045737.1|WP_153652218.1|1192760_1192997_-|Lrp/AsnC-family-transcriptional-regulator
MAVQAYILVQTEVGKAADVAVAIGEIPGVTLAEDVTGPYDVIARAEGPSMDELGSLVVSRIQTVPGITRTLTCPIVRI
>NZ_CP045737.1|WP_153652226.1|1201975_1203160_-|DNA-polymerase-IV
MTEGTVLHADLDAFYASVEQRDDPALRGRPVIVGGGVVLAASYEAKARGVRTAMGGRQALQVCPDAIVVPARFNAYTEASRAVFDVFHDTTPLVEGISIDEAFLEVGGLRRIRGAPSTIATQLRADVRDRVGLPISVGVARTKYLAKVASAVSKPEGMLVVPVEQELTFLHALPVERLWGVGKVTSAKLREARLTTVGDVAEMFEGELVQLLGPGAGRHLHALAHNRDPRPVQTGKRRGSMGAQHAMGRGDHSPADLDLVLLTLVDRVTRRMRAAGRTGSTVTIRLRFGDFTRSTSSHTLARPTAHTVTVLEVARQLLASRAGVIKDKGITLVGVSVGSLDDQPAQLALPLDVTSGAELDDAIDAVRDKFGSTALRRAVQLGRSDPVAAPHLPD
>NZ_CP045737.1|WP_153652227.1|1203166_1203880_+|DUF177-domain-containing-protein
MLPPAADTCASRAIGLGVCRGVTIDLGLLAGLSLVVLLDGWLIVLSGPLVFDTHEMGRKPGAERTFTRTIEAPAEMGYDVYAVPEGSTIELELRLEAIMEGVLATGTFSARAVGECVRCLEPIDEAVVVGFQELFLYEAPSSQEEADEEDHVLEDELLDLEPVLRDAVVLALPHNPLCGPDCPGLCPECGARLADDPDHTHGEAIDPRWSALSQLAEQPVPSADQSESDIASDPSKE
>NZ_CP045737.1|WP_056607529.1|1203883_1204069_+|50S-ribosomal-protein-L32
MAVPKRKMSRSNTRHRRSQWKTTATAIVDCANPACDSKVQPHHACTKCGQYGARGERRQVL
>NZ_CP045737.1|WP_153654989.1|1204065_1204779_+|ribonuclease-III
MISAAADAGALREVLGVQDLDPELLQHALTHRSYAYENGGVPNNERLEFLGDSVLGLVVTDTLFTEHPDLPEGQLAKLRAAVVSAKALAEVARTLGIGEHVRLGRGEETTGGRDKASILSDTVEAILGAIYVQFGIERAAMVIHRVFDPVIADAAKLGAGLDWKTSLQEISANNDLGVPHYVLVGTGPDHNKSFTAEVVVGERTFSGGAGRSKKEAEQMVAEIAWREINAGLDQPVS
>NZ_CP045737.1|WP_153652228.1|1204783_1205650_+|bifunctional-DNA-formamidopyrimidine-glycosylase/DNA-(apurinic-or-apyrimidinic-site)-lyase
MPELPEVEVVRRGIADHVVGRTITGVTVHDVRSVRRHLAGPADFRHRLEGRTVVGAARRGKYLWIQLADPEGGASDAILCHLGMSGQFLVSDASAPPQRHLRITLELDDGNELRFADQRIFGGMSFSEDGAELPPEIAHIARDPLDPLFDPAEFAARIRRRQTGVKRAILDQTLISGVGNIYADEALWRTPLHYARNTRHLRTREIESLLGHIGDVMREALAQGGTSFDALYVNVNGNSGYFDRSLQAYGQEGGPCQRCGTPIRRDPFMNRSSFWCPVCQPRPRNGRF
>NZ_CP045737.1|WP_153652229.1|1205663_1206134_+|GNAT-family-N-acetyltransferase
MSLTLEPMGAAQFASWMNHVMQWYAQGKVDAGSWPEEGAFERARRENAEQLPDGVQTPGNHFFVGTVDGREVGFLWLHSDPDQSPPTATIEAIEVLESERGQGLGRALLEAAEGWCADHSIATLRLHVFGRNTAAINLYESAGFEATNVLMAKTIR
>NZ_CP045737.1|WP_153652230.1|1206130_1207363_+|deoxyguanosinetriphosphate-triphosphohydrolase
MTDQPYGDEAYERFVDEPPKRSGRTSFERDRARVVHSAALRRLSAKTQVMGAGFDDFVRNRLTHSLEVAQVARELGKSLGCDPDVVDSAALAHDLGHPPFGHNGEVALDEAAQNCGGFEGNAQTLRILSRLESKAFGPDGRSVGLNLTRATLSACVKYPWRRGEVPEAAGKFGVYTDDLPVFDWLRDGAPARRRPIEAQVMDLADDIAYSVHDVEDGVVGGWFGLRAGELDIAAIHAVARDWYDGTATDDRLGAALERLQDLPEWPTTSFDGSRAERAVLKSLTSALIGRFAHAAEVATVEAWGGGPLTRFGADLEVPVGTRDEITVLKSIAAHYVMRAHDRAGPLGRQRELLLALVEALDRSEGRALEAEFAQDFARAEDDAARRRVVIDQVASLTDVSARAWGLRLLG
>NZ_CP045737.1|WP_153652231.1|1207414_1209304_+|DNA-primase
MAGRIKDEDIQLVRERTRIDEVVEQYVTLKNAGGGSRKGLCPFHDEKSPSFNVRPSVGSYHCFGCGAGGDVFKFVMELEGLSFVETVERLAAKAGITLRYEEGIGPSGPRRDPNQRNRLLEAHREAGAFYAAALQSSPDAQAGRQFVQDRGFDQAAAEMFGMGFAPRGGEALVAHLRGKGFSEDELVTGGLANRGTRGLYDKFRGRLLWPIREMTGEIIGFGARRMFDDDRVEAKYLNSPETPIYKKSQVLYGIDLARRSISSSSQAVIVEGYTDVMACHLAGVTTAVATCGTAFGEDHARVMRRLMLDDQAFHGEVIFTFDGDEAGQRAALKTFSGDQQFVAQTYVAVEPRGMDPCDLRLADGDAAVRDLVASRIPLYRFVLDNLLGKYDLDRGDQRVDAVREAVGLASAIRDKSKVDALLREIAGRVGTDVDQVRAEHRRRVASAPKGAGQPATQEAPTDALPSPAVNFGQPQFADEREALKAIVQHPHLAARFADDIDDNDFTHPISKLLWKHIEAMPWPTGPNANWLPQLSDSVHDEDAKRILSIAAVEPMRAREGNTGAVVSSILMRLQLLTLGRRIAEIKSKLQRTNPIDEAESYNRMFGDLIALEQQFRTLRDRSLSGDVPS
>NZ_CP045737.1|WP_153652232.1|1209379_1209973_+|hypothetical-protein
MDRFVRELLSLPSLDAEQERALAVRAGEGDRDARADLITAGLRLVALRACLLGLTGEDMRDAVQAGAVGLIRAVDRFDPDRGARLATYAWHWIGAEMSVARPRDVPLGEVDPPYAEPDVLGDSLLDGLSDDAVAVLSLRFGIGPGGGSPMPRIAVAQRLGVSVTRIRTIEGEAMRQLREGLAKVVDRAPLQREADPP
>NZ_CP045737.1|WP_153652233.1|1210286_1210952_+|hypothetical-protein
MGDVLTGPARGLFDAGGRALAAAFGGLARVRPAAKPLHPRGRLYDAAIERRGMDELVGVPWIDEAGVTTGLVRLSRAAGLPSALPDIHGMAIRLPTDGGGHGDLLLATTGLGRITRYVLVPGATADHRSYSTLIPYRTQAGPLNLAAMPAPDEDRAFDLACATTRGTWTVFARMQLAQSPSEDSPSFDPVLNTLPGLAYYDWATRLRERSYRAARHSRADR

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP045737_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045737_5

1237644-1237731

Orphan

Consensus_repeat	Method
ACCGACGATGAGGGTTTGGGGTAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045737_5

>merge|NZ_CP045737|5|1237644-1237731|CRISPRCasFinder
ACCGACGATGAGGGTTTGGGGTAGCTAGCGCAGCCGCAACCCCTCACCCTCGGGCGCGGCCGGCACCGACGATGAGGGTTTGGGGTAG

>NZ_CP045737|5|5|1237644-1237731|CRISPRCasFinder
ACCGACGATGAGGGTTTGGGGTAG	CTAGCGCAGCCGCAACCCCTCACCCTCGGGCGCGGCCGGC
ACCGACGATGAGGGTTTGGGGTAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045737.1\|WP_153652257.1\|1232208_1233309_+\|bifunctional-RNase-H/acid-phosphatase	unknown	unknown	gnl\|CDD\|180903
NZ_CP045737.1\|WP_153652269.1\|1243535_1244828_-\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|227277
NZ_CP045737.1\|WP_153652260.1\|1235205_1235778_-\|UPF0016-domain-containing-protein	unknown	unknown	gnl\|CDD\|225030
NZ_CP045737.1\|WP_153652268.1\|1242185_1243523_+\|type-I-glutamate--ammonia-ligase	unknown	unknown	gnl\|CDD\|223252
NZ_CP045737.1\|WP_153652264.1\|1238708_1238915_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045737.1\|WP_153652265.1\|1238911_1239202_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045737.1\|WP_153652258.1\|1233325_1234099_-\|peroxide-stress-protein-YaaA	unknown	unknown	gnl\|CDD\|234999
NZ_CP045737.1\|WP_153652256.1\|1231438_1232212_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224495
NZ_CP045737.1\|WP_153652253.1\|1227469_1229569_+\|RecQ-family-ATP-dependent-DNA-helicase	unknown	unknown	gnl\|CDD\|223588
NZ_CP045737.1\|WP_153652255.1\|1230641_1231469_+\|Nif3-like-dinuclear-metal-center-hexameric-protein	unknown	unknown	gnl\|CDD\|376614
NZ_CP045737.1\|WP_153652262.1\|1236781_1237615_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|223729
NZ_CP045737.1\|WP_153652272.1\|1248333_1249482_+\|DUF3152-domain-containing-protein	unknown	unknown	gnl\|CDD\|371483
NZ_CP045737.1\|WP_153652266.1\|1239205_1240075_-\|3-methyl-2-oxobutanoate-hydroxymethyltransferase	unknown	unknown	gnl\|CDD\|234723
NZ_CP045737.1\|WP_153652270.1\|1244837_1245266_-\|YciI-family-protein	unknown	unknown	gnl\|CDD\|226318
NZ_CP045737.1\|WP_153652261.1\|1236444_1236621_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045737.1\|WP_153652259.1\|1234124_1235186_-\|arsenic-transporter	unknown	unknown	gnl\|CDD\|238538
NZ_CP045737.1\|WP_153652263.1\|1237808_1238657_-\|type-I-methionyl-aminopeptidase	unknown	unknown	gnl\|CDD\|235576
NZ_CP045737.1\|WP_153652254.1\|1229590_1230601_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381300
NZ_CP045737.1\|WP_153652267.1\|1240343_1242095_-\|NAD+-synthase	unknown	unknown	gnl\|CDD\|237577
NZ_CP045737.1\|WP_153652271.1\|1245377_1248299_+\|bifunctional-[glutamine-synthetase]-adenylyltransferase/[glutamine-synthetase]-adenylyl-L-tyrosine-phosphorylase	unknown	unknown	gnl\|CDD\|237613

Protein	Function_ID	Function_description	E-value
NZ_CP045737.1\|WP_153652257.1\|1232208_1233309_+\|bifunctional-RNase-H/acid-phosphatase	gnl\|CDD\|180903	PRK07238, PRK07238, bifunctional RNase H/acid phosphatase; Provisional.	4.28453e-164
NZ_CP045737.1\|WP_153652269.1\|1243535_1244828_-\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|227277	COG4941, COG4941, Predicted RNA polymerase sigma factor containing a TPR repeat domain [Transcription].	8.02829e-139
NZ_CP045737.1\|WP_153652260.1\|1235205_1235778_-\|UPF0016-domain-containing-protein	gnl\|CDD\|225030	COG2119, COG2119, Predicted membrane protein [Function unknown].	2.59169e-33
NZ_CP045737.1\|WP_153652268.1\|1242185_1243523_+\|type-I-glutamate--ammonia-ligase	gnl\|CDD\|223252	COG0174, GlnA, Glutamine synthetase [Amino acid transport and metabolism].	0
NZ_CP045737.1\|WP_153652271.1\|1245377_1248299_+\|bifunctional-[glutamine-synthetase]-adenylyltransferase/[glutamine-synthetase]-adenylyl-L-tyrosine-phosphorylase	gnl\|CDD\|237613	PRK14109, PRK14109, bifunctional [glutamine synthetase] adenylyltransferase/[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase.	0
NZ_CP045737.1\|WP_153652266.1\|1239205_1240075_-\|3-methyl-2-oxobutanoate-hydroxymethyltransferase	gnl\|CDD\|234723	PRK00311, panB, 3-methyl-2-oxobutanoate hydroxymethyltransferase; Reviewed.	4.41865e-165
NZ_CP045737.1\|WP_153652256.1\|1231438_1232212_+\|hypothetical-protein	gnl\|CDD\|224495	COG1579, COG1579, Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only].	6.32374e-25
NZ_CP045737.1\|WP_153652253.1\|1227469_1229569_+\|RecQ-family-ATP-dependent-DNA-helicase	gnl\|CDD\|223588	COG0514, RecQ, Superfamily II DNA helicase [DNA replication, recombination, and repair].	1.65011e-132
NZ_CP045737.1\|WP_153652255.1\|1230641_1231469_+\|Nif3-like-dinuclear-metal-center-hexameric-protein	gnl\|CDD\|376614	pfam01784, NIF3, NIF3 (NGG1p interacting factor 3). This family contains several NIF3 (NGG1p interacting factor 3) protein homologs. NIF3 interacts with the yeast transcriptional coactivator NGG1p which is part of the ADA complex, the exact function of this interaction is unknown.	8.58657e-79
NZ_CP045737.1\|WP_153652262.1\|1236781_1237615_+\|aldo/keto-reductase	gnl\|CDD\|223729	COG0656, ARA1, Aldo/keto reductases, related to diketogulonate reductase [General function prediction only].	6.3211e-137
NZ_CP045737.1\|WP_153652272.1\|1248333_1249482_+\|DUF3152-domain-containing-protein	gnl\|CDD\|371483	pfam11350, DUF3152, Protein of unknown function (DUF3152). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently there is no known function.	5.31116e-20
NZ_CP045737.1\|WP_153652258.1\|1233325_1234099_-\|peroxide-stress-protein-YaaA	gnl\|CDD\|234999	PRK02101, PRK02101, peroxide stress protein YaaA.	1.6044e-64
NZ_CP045737.1\|WP_153652270.1\|1244837_1245266_-\|YciI-family-protein	gnl\|CDD\|226318	COG3795, COG3795, Uncharacterized protein conserved in bacteria [Function unknown].	2.81589e-30
NZ_CP045737.1\|WP_153652259.1\|1234124_1235186_-\|arsenic-transporter	gnl\|CDD\|238538	cd01118, ArsB_permease, Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in eubacteria and archaea. A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump (ArsAB). The ArsAB complex is similar in many ways to ATP-binding cassette transporters, which have two groups of six transmembrane-spanning helical segments and two nucleotide-binding domains. The ArsB proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life.	2.21716e-43
NZ_CP045737.1\|WP_153652263.1\|1237808_1238657_-\|type-I-methionyl-aminopeptidase	gnl\|CDD\|235576	PRK05716, PRK05716, methionine aminopeptidase; Validated.	2.16231e-147
NZ_CP045737.1\|WP_153652254.1\|1229590_1230601_+\|aldo/keto-reductase	gnl\|CDD\|381300	cd19074, Aldo_ket_red_shaker-like, Shaker potassium channel beta subunit family and similar proteins. This family includes voltage-gated potassium channel subunits, beta-1 (KCAB1B), beta-2 (KCAB2B) and beta-3 (KCAB3B). KCAB1B and KCAB2B are cytoplasmic potassium channel subunits that modulate the characteristics of the channel-forming alpha-subunits. KCAB3B is an accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. The family also includes Drosophila melanogaster Hk protein, a founding member of aldo-keto reductase family 6 member B1 (AKR6B1), as well as voltage-gated potassium channel subunit beta (KCAB) from Arabidopsis thaliana and Egeria densa, founding members of AKR6C1and AKR6C2, respectively. Hk protein, also called hyperkinetic, is a beta subunit of Shaker (Sh) K+ channels and shows high sequence homology to aldoketoreductase. KCAB, also called Shaker channel b-subunit, or K(+) channel subunit beta, or potassium voltage beta 1, or KV-beta1, or KAB1, is a probable accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit.	2.74116e-166
NZ_CP045737.1\|WP_153652267.1\|1240343_1242095_-\|NAD+-synthase	gnl\|CDD\|237577	PRK13981, PRK13981, NAD synthetase; Provisional.	0

>NZ_CP045737.1|WP_153652262.1|1236781_1237615_+|aldo/keto-reductase
MTVPNIALNNGVEIPQLGFGVFQIDPSETKDATLTALEVGYRHIDTAEMYGNEKEVGEAIRESGIPRDEIFVTSKLNNGFHAPDDAVKAFEGTLEALGLDKIDLFLIHWPLPGIDVDFVDTWKTLEGFYRDGRARSIGVSNFQPTHLRRVIQEGEIVPAVNQIEVHPYLTQDEVRAVNTEHGVATEAWSPIAQGLVLDNPVVTGLANDKGKTPAQVVLRWHVQRGDIIFPKSVTRSRVEENFDIFDFELTDGEMGTISALNKDERTGPDPDVFNYIP
>NZ_CP045737.1|WP_153652261.1|1236444_1236621_+|hypothetical-protein
MTTTFTPQDVADPGDDLLGRIRLRKVFAGTLLEPSWKFPSSYEPAAEQTLGSLRVEQA
>NZ_CP045737.1|WP_153652260.1|1235205_1235778_-|UPF0016-domain-containing-protein
MYAFLLSTAVIFVAELGDKSQLMAMTFATRYKVRDVIIGISVATAIVHLASVGIGAWIGDSFADSQHIISIVAGVAFLLFAAWTWRGDELTEGEADKARLSQGAAILAVGVAFFLAELGDKTMLATITLATQEGWLGTWIGSTVGMVAADALAIGVGAILGKHLPDRAIKIGATAAFVVFGVLLILEGVL
>NZ_CP045737.1|WP_153652259.1|1234124_1235186_-|arsenic-transporter
MTHDLGSLTAIVAFLVAMMVLARACADEGLFDVLGRHIASWSHGSAHRLLALAVGLAAVVTATMSLDATVVLLTPVLLAASARRSYAYATVRLANSGSTLLPVSNLTNLLVFGSTGLTFLGFAWAMLPVWVVAVAAEYVILRFWFADELRTPAPALEDDFALPLFPLAVVVVVLLALAGGTDPWIPATAGAILVGTYALVRRRTSWRDLRAAANLPLAALVLTWAFVVSWLGSTPVGAWFDDAMPSGTGLGSLLIVAVVAMIAANVVNNLPATLLLLPAADAAGPAAVLALLVGVNVGANLTLIGSVANLLWRQAGGKAVSSVREFHLLGVLTTPPLVLLCTVVLWAWTSLIW
>NZ_CP045737.1|WP_153652258.1|1233325_1234099_-|peroxide-stress-protein-YaaA
MLILLPPSEGKTRPESGSPLDLETLSFPALTPVREVLLRSLVKLCNGKPEHAAEVLGLGPTQAGAIAVNAALTNEPTARADAIYTGVLFSALDLPSLDEAARGRADSTIAIASALFGLVRPDDHIPAYRLSGTVTLPRLGTVAARWRTTLPQVMQDEVGDGLLVDLRSGTYTALGKPPADITGRTATMRVLHEHQGKRKVVSHFNKATKGRIVRGLMESGADPRSVDELQGVLQDLGWTVERHGGRLDVVVDEVATS
>NZ_CP045737.1|WP_153652257.1|1232208_1233309_+|bifunctional-RNase-H/acid-phosphatase
MTDRVILEADGGSRGNPGPASYGALIRDAGTGRVIAQRGETIGRATNNVAEYSGLIAGLELYREHTPDARLEVRMDSKLVIEQMAGRWRIKHADMIPLAEKARRLAPADVTWTWVPRERNKDADALANAALDDERDGGSGVVSGSGTSAAAPSAPSTGWSAAGGRPTTLVLVRHGVTSATERKAFSGSTGDDHGLTDAGRQQADRAAAWIAERGPVDAIVTSPLLRTRETAAVIGSDLGLDVSVESGLAETSFGDWDGYTFAEIQERWPEEMSAWLASTDVAPPGGESFAEVDRRITATREALLAAHPGETVVAVSHVTPIKLLVRHALGAPLASIYKMELSPASITTVAWWPDGNASLRGFNIVP
>NZ_CP045737.1|WP_153652256.1|1231438_1232212_+|hypothetical-protein
MDRDRAGYGVRVKADPTAQAALLALQSTDAILSQLQHRRNNLPEHARIKELEAQIKDVDGTRIELDTQVSDLSRAQKKADAEVEQVKARRTRDEERLNSGAVKNPKDLESLQHELVALERRISTLEDDELEVMEKLEDAQTGLASVQADLDSLKTELAEQVSARDTAIEVIDQQVAEAQSERGSTAEVIPADLITLYDKLRGQYGTGAAALRARRCEGCRLELNGADLRELAAAPEDDVLRCPECSRILVRTPESGL
>NZ_CP045737.1|WP_153652255.1|1230641_1231469_+|Nif3-like-dinuclear-metal-center-hexameric-protein
MPTPLLRDVVAVLDELYDPSWADDWDAVGTVAGDPQAEVGRVLLAVDPVSAVVDEAIAWGADLIVTHHPLWLKGVTSVAATSPKGRVVHNLITHGIALHACHTNADSPRLGVSESMAYALGLFDVRPLEPDTDDEQPDRGSGRIGVLQSPTTLAAFSEHVARSLPSHRSAVRVAGDPGRPVRTVALCGGSGDFLLGAAQAQGADVYVTSDLRHHPVSEHLEQPDPCAVIDVPHWSAEWTWLPVAASALAERLPEVEVKVSTIVTDPWTAIVPGTV
>NZ_CP045737.1|WP_153652254.1|1229590_1230601_+|aldo/keto-reductase
MEHRYLGNSGLKISEIAYGNWLTHGSQVEEDAATACVRQALDEGITTFDTADVYANTKAESVLGRALAGQRRESLEILTKVYWTTGPGGPNDSGLSRKHIMESINGSLTRLQTDYVDLYQAHRYDIETPLEETMQAFADVVRAGKALYIGVSEWTADQIRDGQELAHQLGFSLISSQPQYSMLWRVIEDEVVPASEELGLSQIVWSPIAQGVLTGKYKPGQPVPEGSRATDDQGGAQNISRWMKDHVLEAVQRLQPIAHAADLTMAQLAVAWVLRRPNIAAAIIGASRPEQVTDNAKASGVVLGDDVMEAIDDALGDVVVRDASFTARQTPDTRPT
>NZ_CP045737.1|WP_153652253.1|1227469_1229569_+|RecQ-family-ATP-dependent-DNA-helicase
MTTEADATTALRRLTGRDDAVFHDGQLEAIEALVDGHRRALVVQRTGWGKSAVYFISTLLLRQRGAGPTLLVSPLLALMRDQVAAAARAGVRAVAINSANPHEWEETRAKLAADEVDILLVSPERLNNPRFRDEQLPALVERMGMLVVDEAHCISDWGHDFRPDYRRLAELIAKLPDDLPVLATTATANARVVTDVAEQLGAEGEVLTIRGSLARTSLRLGVLELPGARDRLGWLLSHLAELPGSGIIYALTVSNAEDTARLLREGGHAVRAYTGRTDPEQREELERQLKDNEIKALVATSALGMGFDKPDLGFVIHLGAPSSPVAYYQQVGRAGRATDNADVLLLPGREDRDIWTYFATSSMPSEERAAAVIDALGDETLSTPALEARVNLRRSPLELLLKVLDVDGAVRRVQGGWVATGVPWTYDRERYERIAAARDAEQQSMLTYQRDTTCRMEMLQRDLDDPTASPCGRCDNCTTPWYPTGIDPAATQAASSTLDKVGVEIEPRAQWPSGAERLGVEAKGKIPVDDRAEPGRAVARLTDLGWGNVLRELFAAGAPDGPVTDELLGACVRVLKDWGWDERPAAVVSIPSRSRPQLVDSLARGIARIGRLTDLGSLDQVGPEPRGGPGGNSAYRLADVWGTFAVGPALADGLRELGGRPVLLIDDRVDSRWTLTVAARELRRSGAGAVLPLALAVVA
>NZ_CP045737.1|WP_153652263.1|1237808_1238657_-|type-I-methionyl-aminopeptidase
MSVLTAGRVSARRPVPASIERPEYVGQIAPLPYRGPLVRDAETIEAMRIAGRIAAQALDAVEAAIAPGVTTDELDRIGHEFIVAQGAYPSTLGYRGYPKSLCSSVNEVICHGIPDDRPLEDGDIVNIDITAYIGGVHGDTNKTYLVGDVDQESRLLVERTQEATMRAIRAVKPGREINVIGRVIETYAKRFGYGVVRDFTGHGVGPAFHDGLVIPHYDDPSADTVMQPGMTFTIEPMLTLGSIDWDMWDDGWTATTRDRSRTAQFEHTLLVTSNGAEILTLS
>NZ_CP045737.1|WP_153652264.1|1238708_1238915_+|hypothetical-protein
MSDAKFYYCTKHGTVEGEDGCRAADRLGPYDTAEEAARALEIAAERTKSWDNDPDWNDDATPDEPTKE
>NZ_CP045737.1|WP_153652265.1|1238911_1239202_+|hypothetical-protein
MRRRRRRRSGGLRLERSGPWIAVGGLFVLLWLAISTSIYAPWWGVVLHVLILAPLVGWVVSWARTRPAACTFVPLAGLPLLALVTAVGVGPGGWSA
>NZ_CP045737.1|WP_153652266.1|1239205_1240075_-|3-methyl-2-oxobutanoate-hydroxymethyltransferase
MADATPEETAPYGTGPASPAPAARKRVRTHTLQQMKERGEKWTMLTAYDQYTAATFDEAGVEVLLVGDSASNNVYGNETSLPVTVDELIPLVRAVSRSAPHALVLADLPFGSYQGSPEQAFHTAVRFMKEAGAHAVKLEGGLAMVPQVKLLTDAGIPVCAHIGFTPQAEHNLGGYRVQGRGDGAARMVEEARALEAAGAFAIVMEMVPSPVAAEVTKALRIPTVGIGAGVECDAQVLVWQDMLGLNSGRTPRFVKKYADLHAVMLQATQAYVSDVKGGTFPDDEHSFAE
>NZ_CP045737.1|WP_153652267.1|1240343_1242095_-|NAD+-synthase
MPQLRLALAQVNATVGDLAGNADLVVEHCKDAAARGVHLVVFPEMMLTGYPIEDLAMRASLIKASRATAESLATRLQDEGCGDVVAVVGFLDHAEDSSQGFGIPKNAPLNSVAVMHGGRIVARQAKHHLWNYGVGDEIRNFVPGHEINILQIGGIDVALAICEDLWRDGPSAAAKAAEAALLVVPNGSPYEADKDDVRLELCSRRAREGECVLAYVNLVGGQDELVFDGDSLVVDQDGSVLGRSGQFDPELLVVDLDLPAATPAMPDAEERFGGLAIRRTIISSEPFAAYEPLPVTQAERMPRHQEIWTALVTGLRDYVHKNGFSSVLFGMSGGIDSTLVAAIAVDALGADKVFGVSNPSAWSTEHSRSDAAEQARRTGLTLQTVPIAPIFDAYQEALHLDGLAEENLQARIRAVIWMGLSNQHGHLVLACGNKSELATGYSTIYGDAVGGYAPIKDVPKTLVWELARWRNAYAVERGETPPIPEGTISKPPSAELRPGQLDSDSLPPYDQLDAVLDAYVERDLGSADVIAEGFDPALVERVIGLVDRAEYKRRQYPPGPKVSRRNFGRDRRVPITHRWREKL
>NZ_CP045737.1|WP_153652268.1|1242185_1243523_+|type-I-glutamate--ammonia-ligase
MGKQEDFVLRALEERDVRFVRLWFTDVLGSLKSVAIAPAELEGAFAEGIGFDGSAIEGFARVHEADMLAMPDPSTFQILPWRGETPATARMFCDILMPDGTPSYADPRHVLKRALQKAAEAGFTFYTHPEIEFFLFKGKPDAGDRPVPVDDSGYFDHTAQGGGQDFRREVITMLENMGISVEFSHHEGGPGQQEIDLRYADALSTADNIMTFRTVVREVALSQGKWASFMPKPFTEHPGSGMHTHVSLFEGDENAFYEAGAEYQLSRTGRAFIAGVLHHTPEITAVTNQWVNSYKRLAGGGEAPNYVCWGHNNRSALIRVPMYKPHKGNSARVENRAVDSACNPYLAFALILAAGLKGIEEKYELPPEAEDDVWSLSENERKAMGIAPLPRNLDEAIRTMETSELVAETLGEHVFDFFLRNKRAEWQDYRSQVTQFEIDRLMPMV
>NZ_CP045737.1|WP_153652269.1|1243535_1244828_-|sigma-70-family-RNA-polymerase-sigma-factor
MAEDRAVAASESEAAAARRRVEALWRIESARIVATLTRVVGDFGLAEDLAQEAFVDALAQWPRDGVPPNPAAWLTTVAKRKGIDRRRRLARLDDRHAAIAYSLAEQHRLAAIDHEPPWDPETVDDDVLRLIFTACHPILPRESQIALTLRVVGGLTTEEIARAFMVPVSTVQQRIVRAKRTISAAAVPFEVPSREELGGRLASVLQVVYLIFNEGYAATAGSSWMRTDLAGEALRLARIVSSLVPDEPDAHALRALLELQASRFAARVDADGEPVLLADQDRSRWDHDQIRRGRAALAKADAIGRGRGAYALQAAIAECHAVAPSTDGTDWARIVGLYESLAEVAPSPVVDLNRAVAVAMAHGPAAGLAAVDELVATGAMTGSALLPGVRGELLARLGRRDEAREELLAATALTRNERERAVLLQKAERI
>NZ_CP045737.1|WP_153652270.1|1244837_1245266_-|YciI-family-protein
MKYMLIMRTPEMVEMPEDVDFTEVINAMGAYNESLIKAGVLLAGEGLAPPDEGFVVDFDATPPVVTDGPYAEAKELFNGFWMIQTSTKEEAAEWAKRCPLGPGMRLEVRRVNETEEFDQDNEYVQKEHEWREQLGTDRPVQG
>NZ_CP045737.1|WP_153652271.1|1245377_1248299_+|bifunctional-[glutamine-synthetase]-adenylyltransferase/[glutamine-synthetase]-adenylyl-L-tyrosine-phosphorylase
MATDARDLAVTLARKGFRDGQAAVASLESLGDVPEALVDQIASVASPDAALSSLSSIASRMALGELLEMLASDDELRLRLLVVLGTSEALGDFLTRHPEHVRDLASTDLARRPIPLDLRRQQMEEATDADELRVAYHRKLLHIAARDLTALTTFEESSAELSDLAVATLGAALRIAREAEPDADLCRLTIIAMGKTGGHELNYLSDVDVIFVHEPAEGADDGAAIGAATRLAAAVMKLCREHTGEGTIWEVDAELRPEGKNGPLVRTLASHIAYYEKWASTWEFQALLKARFGAGDEELGQAYIDALSPMIWLASTRPHFVSDVRAMRRRVIDNIPAAQRSRQLKLGAGGLRDVEFAVQLLQLVHGRADETLRSPTTLKALGALIDGGYVGRRDGAAMEEAYEFLRTLEHRIQLYKLRRSHIVPDDPEDLRRLGRSMGFRQNSAEALTKEWQAHRRIVRRLHEKLFYQPLLEAVASLPTDHLRLTPLAAEERLTALGFVDPKGALAHIQALTSGLSRRASIQKSLLPAMLAWFAESPDPDAGLLAFRKISEGLGETHWYLRKLRDEGEGAEQLAHVLSSSRYVTDLILRAPDSVALLGDDAELRPLERERLRTEVDLAADRHRNPQDAIRAVRRVRRRELSRVGIADVLGRLDITEVGEALTDISTATLAGALKASTAAVEAERGEMPTRLSIVLMGRLGGGEAGYGSDADVMFVHDPCEGADDTEAAAAATAVVQGLRRMLAAPGDDPALEVDAELRPEGKNGPLVRTFASYRAYYEKWSAVWEAQALLRANAAVGDADLNARFTELIDPLRFPEGGATADEIREIRRIKARVDSERLPRGANPKTHLKLGRGGLADVEWTVQLLQMQHAHAVPELRTTRTLTALHAAVGADLVSHDDAMALEAAWRLVSRIRNAVVLMRGKAAESMVEHAGERAGVAHLLGYGMDEGERLNDDYLRTTRHARKVVERIFYE
>NZ_CP045737.1|WP_153652272.1|1248333_1249482_+|DUF3152-domain-containing-protein
MGSTIMRRSVRAVIALVITVLAASLLAAPASAADEAIVPGTPTVSGRAQYDGTLTAVPGAWTPGDVTFSYQWLRDGAPVGSDSPANVTRRLTSTNDIGRTYAVRVTATRDGSAPVAATSARTRPVAKGTITRTARPKISGSPRYGHRLTGTSGSWSRGVRLEYRWLRNDKPISGATGRHHTVGPSDVGAKIRFRVKAKRTGYSTATARSTAVTGQHVRSVRKVVTYRVATRGSISTSLTTFKRQAQETYDDPRGWRAMGVRFKRVSKGGDFTLVLSQASKVPSFSSGCSSTYSCRVGRNVIINQTRWLKASPAWKSRKGSVRSYRHLVVNHETGHWFGRGHVGCGGKGQAAPVMQQQSKGLGGCTINPWPKKNELHAPRYGW

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP045737_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045737_6

1400453-1400541

Orphan

Consensus_repeat	Method
GCACCGCGAACGCACAAAGATCGGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045737_6

>merge|NZ_CP045737|6|1400453-1400541|CRISPRCasFinder
GCACCGCGAACGCACAAAGATCGGTGACACCGGCGACGGACGTTTCGGCGTTTGCGCAGCCCCCGCACCGCGAACGCATAAAGATCGGT

>NZ_CP045737|6|6|1400453-1400541|CRISPRCasFinder
GCACCGCGAACGCACAAAGATCGGT	GACACCGGCGACGGACGTTTCGGCGTTTGCGCAGCCCCC
GCACCGCGAACGCATAAAGATCGGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045737.1\|WP_153652403.1\|1395426_1396752_+\|histidinol-dehydrogenase	unknown	unknown	gnl\|CDD\|234853
NZ_CP045737.1\|WP_153652417.1\|1408337_1409564_+\|tryptophan-synthase-subunit-beta	unknown	unknown	gnl\|CDD\|235288
NZ_CP045737.1\|WP_153652404.1\|1396751_1397828_+\|histidinol-phosphate-transaminase	unknown	unknown	gnl\|CDD\|235115
NZ_CP045737.1\|WP_153652414.1\|1406247_1406943_+\|RDD-family-protein	unknown	unknown	gnl\|CDD\|377640
NZ_CP045737.1\|WP_153654997.1\|1394897_1395344_-\|Cys-tRNA(Pro)-deacylase	unknown	unknown	gnl\|CDD\|237976
NZ_CP045737.1\|WP_153652401.1\|1390814_1394351_+\|DNA-polymerase-III-subunit-alpha	unknown	unknown	gnl\|CDD\|235554
NZ_CP045737.1\|WP_153652400.1\|1390205_1390613_-\|DUF1801-domain-containing-protein	unknown	unknown	gnl\|CDD\|227933
NZ_CP045737.1\|WP_153652405.1\|1397824_1398448_+\|imidazoleglycerol-phosphate-dehydratase-HisB	unknown	unknown	gnl\|CDD\|234873
NZ_CP045737.1\|WP_153652409.1\|1400562_1401324_+\|imidazole-glycerol-phosphate-synthase-subunit-HisF	unknown	unknown	gnl\|CDD\|234996
NZ_CP045737.1\|WP_153654998.1\|1401421_1403185_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP045737.1\|WP_153652411.1\|1405016_1405382_+\|phosphoribosyl-AMP-cyclohydrolase	unknown	unknown	gnl\|CDD\|234598
NZ_CP045737.1\|WP_153652402.1\|1394364_1394901_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045737.1\|WP_153652406.1\|1398444_1399080_+\|imidazole-glycerol-phosphate-synthase-subunit-HisH	unknown	unknown	gnl\|CDD\|237290
NZ_CP045737.1\|WP_153652407.1\|1399144_1399870_+\|bifunctional-1-(5-phosphoribosyl)-5-((5--phosphoribosylamino)methylideneamino)imidazole-4--carboxamide-isomerase/phosphoribosylanthranilate-isomerase-PriA	unknown	unknown	gnl\|CDD\|237589
NZ_CP045737.1\|WP_153652413.1\|1406002_1406206_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045737.1\|WP_153652416.1\|1407459_1408269_+\|indole-3-glycerol-phosphate-synthase-TrpC	unknown	unknown	gnl\|CDD\|234710
NZ_CP045737.1\|WP_153652408.1\|1399873_1400407_+\|DUF1707-domain-containing-protein	unknown	unknown	gnl\|CDD\|377959
NZ_CP045737.1\|WP_153652410.1\|1403181_1405020_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP045737.1\|WP_153652412.1\|1405285_1405960_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378200
NZ_CP045737.1\|WP_153652415.1\|1406946_1407372_+\|DUF2752-domain-containing-protein	unknown	unknown	gnl\|CDD\|378499

Protein	Function_ID	Function_description	E-value
NZ_CP045737.1\|WP_153652403.1\|1395426_1396752_+\|histidinol-dehydrogenase	gnl\|CDD\|234853	PRK00877, hisD, bifunctional histidinal dehydrogenase/ histidinol dehydrogenase; Reviewed.	0
NZ_CP045737.1\|WP_153652417.1\|1408337_1409564_+\|tryptophan-synthase-subunit-beta	gnl\|CDD\|235288	PRK04346, PRK04346, tryptophan synthase subunit beta; Validated.	0
NZ_CP045737.1\|WP_153652404.1\|1396751_1397828_+\|histidinol-phosphate-transaminase	gnl\|CDD\|235115	PRK03317, PRK03317, histidinol-phosphate aminotransferase; Provisional.	0
NZ_CP045737.1\|WP_153652416.1\|1407459_1408269_+\|indole-3-glycerol-phosphate-synthase-TrpC	gnl\|CDD\|234710	PRK00278, trpC, indole-3-glycerol phosphate synthase TrpC.	2.11465e-117
NZ_CP045737.1\|WP_153654997.1\|1394897_1395344_-\|Cys-tRNA(Pro)-deacylase	gnl\|CDD\|237976	cd00002, YbaK_deacylase, This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS) inserted (INS) editing domain. The bacterial amino acid trans-editing enzyme YbaK is a deacylase that hydrolyzes cysteinyl-tRNA(Pro)'s mischarged by prolyl-tRNA synthetase. YbaK also hydrolyzes glycyl-tRNA's, alanyl-tRNA's, seryl-tRNA's, and prolyl-tRNA's. YbaK is homologous to the INS domain of prolyl-tRNA synthetase (ProRS) as well as the trans-editing enzyme ProX of Aeropyrum pernix which hydrolyzes alanyl-tRNA's and glycyl-tRNA's.	1.63051e-69
NZ_CP045737.1\|WP_153652401.1\|1390814_1394351_+\|DNA-polymerase-III-subunit-alpha	gnl\|CDD\|235554	PRK05673, dnaE, DNA polymerase III subunit alpha; Validated.	0
NZ_CP045737.1\|WP_153652400.1\|1390205_1390613_-\|DUF1801-domain-containing-protein	gnl\|CDD\|227933	COG5646, COG5646, Uncharacterized conserved protein [Function unknown].	4.97436e-20
NZ_CP045737.1\|WP_153652405.1\|1397824_1398448_+\|imidazoleglycerol-phosphate-dehydratase-HisB	gnl\|CDD\|234873	PRK00951, hisB, imidazoleglycerol-phosphate dehydratase HisB.	9.07785e-115
NZ_CP045737.1\|WP_153652409.1\|1400562_1401324_+\|imidazole-glycerol-phosphate-synthase-subunit-HisF	gnl\|CDD\|234996	PRK02083, PRK02083, imidazole glycerol phosphate synthase subunit HisF; Provisional.	1.698e-162
NZ_CP045737.1\|WP_153654998.1\|1401421_1403185_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	2.27031e-134
NZ_CP045737.1\|WP_153652411.1\|1405016_1405382_+\|phosphoribosyl-AMP-cyclohydrolase	gnl\|CDD\|234598	PRK00051, hisI, phosphoribosyl-AMP cyclohydrolase; Reviewed.	4.24423e-68
NZ_CP045737.1\|WP_153652406.1\|1398444_1399080_+\|imidazole-glycerol-phosphate-synthase-subunit-HisH	gnl\|CDD\|237290	PRK13146, hisH, imidazole glycerol phosphate synthase subunit HisH; Provisional.	1.17986e-109
NZ_CP045737.1\|WP_153652407.1\|1399144_1399870_+\|bifunctional-1-(5-phosphoribosyl)-5-((5--phosphoribosylamino)methylideneamino)imidazole-4--carboxamide-isomerase/phosphoribosylanthranilate-isomerase-PriA	gnl\|CDD\|237589	PRK14024, PRK14024, phosphoribosyl isomerase A; Provisional.	9.18792e-163
NZ_CP045737.1\|WP_153652414.1\|1406247_1406943_+\|RDD-family-protein	gnl\|CDD\|377640	pfam06271, RDD, RDD family. This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N-terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown. However this region may be involved in transport of an as yet unknown set of ligands (Bateman A pers. obs.).	2.02674e-25
NZ_CP045737.1\|WP_153652408.1\|1399873_1400407_+\|DUF1707-domain-containing-protein	gnl\|CDD\|377959	pfam08044, DUF1707, Domain of unknown function (DUF1707). This domain is found in a variety of Actinomycetales proteins. All of the proteins containing this domain are hypothetical and probably membrane bound or associated. Currently, it is unclear to the function of this domain.	2.40235e-12
NZ_CP045737.1\|WP_153652410.1\|1403181_1405020_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	5.86239e-142
NZ_CP045737.1\|WP_153652412.1\|1405285_1405960_+\|hypothetical-protein	gnl\|CDD\|378200	pfam09534, Trp_oprn_chp, Tryptophan-associated transmembrane protein (Trp_oprn_chp). Members of this family are predicted transmembrane proteins with four membrane-spanning helices. Members are found in the Actinobacteria (Mycobacterium, Corynebacterium, Streptomyces), always associated with genes for tryptophan biosynthesis.	2.47517e-27
NZ_CP045737.1\|WP_153652415.1\|1406946_1407372_+\|DUF2752-domain-containing-protein	gnl\|CDD\|378499	pfam10825, DUF2752, Protein of unknown function (DUF2752). This family is conserved in bacteria. Many members are annotated as being putative membrane proteins.	6.19267e-15

>NZ_CP045737.1|WP_153652408.1|1399873_1400407_+|DUF1707-domain-containing-protein
MAAADVWLTFSADPRESASADLKASDADRDVAAAALREAYADGRLTRDEYDDRSSTALGVRSLGGFLPLLVDLFPSGPAPVPAVSTQLRSEALVTYRRDLRDARNGWLFVSGLCTAIWAATSGAAGELLFFWPVFPSLGVGIGYASTRLNAESRIEAIEDKLAESRRARRRDDDSPT
>NZ_CP045737.1|WP_153652407.1|1399144_1399870_+|bifunctional-1-(5-phosphoribosyl)-5-((5--phosphoribosylamino)methylideneamino)imidazole-4--carboxamide-isomerase/phosphoribosylanthranilate-isomerase-PriA
MTLELLPAVDVADGQAVRLVQGELGSETAYGSPLDAALQWQTDGAEWIHLVDLDAAFGKGSNRELLAEVVGRLDVKVELSGGIRDDASLEAALATGCTRVNLGTAAIENPDWCAKAIGQYGDRIAVGLDVRGTTLAARGWTEEGGDLFEVLARLERDGCARYVVTDVTKDGTLTGPNLDLLRQVCEQTDKPVVASGGVSSLQDLRDIATLTGVGVEGAIVGKALYAGAFTLPEALAAVRES
>NZ_CP045737.1|WP_153652406.1|1398444_1399080_+|imidazole-glycerol-phosphate-synthase-subunit-HisH
MTRPRVAVLDYGSGNLRSAVRAVERAGAEVELTADARVAAEADGLLVPGVGAFESCMKGLEAVDGVRIIERRLIAGRPVLGICVGMQILFAEGIEHGVRTKGCGEWPGVIERLQAPIVPHMGWNTVEPGEGSRMFAGLEDERFYFVHSYGLRDWVLSQPPAFPDPQVTWTEYAEERFVSAVEHGPLWATQFHPEKSGDAGLRLLQNWLATL
>NZ_CP045737.1|WP_153652405.1|1397824_1398448_+|imidazoleglycerol-phosphate-dehydratase-HisB
MTLRKTSREARTARIERKTSESHVVVEVDLDGTGANDISTGVGFYDHMLTAFSRHSLIDLTVRTEGDLHIDAHHTVEDTAICLGQALREALGDKAGIKRYGDSLVPLDESLAQAVVDVSGRPYFVHSGEPERQITAIIGGQYSGSLTAHVLESIAHHAAVTMHVRLVEGRDPHHIAEAQFKAVARAFREAIALDPRESGVPSTKGAL
>NZ_CP045737.1|WP_153652404.1|1396751_1397828_+|histidinol-phosphate-transaminase
MPVPDWVPIREELRDDEPYGAPQLDVPVQLNTNENPYGPSEETARDIADSVLRVATTLNRYPDREATELRTSLAAYLGHGLTADQVWAANGSNEVMQQVLQAFGGPGRTAVSFAPTYSMYPEYARNTHTRWVAGRRRDDFGIDVDAALELIAAEKPDVVILTSPNNPTGSALDPAHTRAVLEAAPGVVVVDEAYAEFRRDGTPSALELLDKFPRLLVTRTMSKAFALAGGRLGYVAADAAIIDALRIVRLPYHLSAVSQAAATAALRHRDELLAQVDALRTTRDETADWLRAEGFEVADSDANFILFGRFEDRHQVWQGLLDRGVLIREVGPLGWLRVSIGTPQDMQAFRTALQEVTR
>NZ_CP045737.1|WP_153652403.1|1395426_1396752_+|histidinol-dehydrogenase
MRRLDLRELDPSADEAPAVYSAAVPRAAVDVEHALAAVRPICDDVRRRGTQAVLDAGEKFDGVRPEQLRVPAAALSDALADLAPEIRAALEESIRRLRQTCAAELEQSLVTDVAPGATVERRIVPMQRVGLYVPGGLAPLVSTVIMNAVPAQVAGVPGIALASPPQSEFGGLPHPTILAACALLGIDEVYAAGGAQALAMFAYGASSDDGVDCRPVNLITGPGNIYVAAAKRHLQGTVSIDSEAGPTEIAIIADDTADPAFIAADLISQAEHDPMAASVLITDSEVLATAVEVEVDLQVEDAKHADRITTALDGPQSATVLVRDLDQAVDVANGYAAEHLEIQTADAGQVAARIVNAGAIFVGSHTPVSLGDYAAGSNHVLPTAGCACHSSGLSVRAFCKNMHVVTYSEAALREVGDHVVTLAEAENLPSHGAAVSIRTSR
>NZ_CP045737.1|WP_153654997.1|1394897_1395344_-|Cys-tRNA(Pro)-deacylase
MLHRAGIDFTPHSYVHDPRAESFGMEAARALGVEPARVFKTLMAVVDGELCVGVVPVMGSLDLKALAEALGGKRAQMADAAQAQRATGYVIGGISPVGQKKQHRTVVDRSASRWETVFVSGGRRGLEAEVRPEDLVRVTGAVTARIAR
>NZ_CP045737.1|WP_153652402.1|1394364_1394901_+|hypothetical-protein
MSEPSLPTSNPPRVTPAVPRRVVLAAVVMLLLGVVGGLVWVWLADPAQWQVTSRGIVMSESESQGQFGVIVVFVAIGAVVSLGWGWVTGRRLEELGWVLTPFVVVVTVLAALLAWRIGVELGPPDPATVARPSVGDRIPAQLKIDGIVPFLVWPIFGLIGLVGAVWSTRREPDPATYA
>NZ_CP045737.1|WP_153652401.1|1390814_1394351_+|DNA-polymerase-III-subunit-alpha
MSSDSSFVHLHVHTEYSMLDGAALLDGLFERTAELGMPSIAMTDHGNLHGAYDFYSKAKAHGVKPIIGMEAYLTPNIPRHEKKAVLWNKGARDADVAGRGAYTHMTLLSETTEGMHNLFRIGSYASLEGQYRKPRADRDLLQRYGKGLIATTGCPSGEIQTWLRIGNYEKARASAAEFQDIFGKENFFLELMDHGLEIERTVRDGLLRLKADLDLPAIATNDSHYTSPEDAEAHSALLCVQSGSTLTDPNRFKFDSNDFYIKSAAEMRDLWEDRFDLKEACDNTLLIAERCNVEFTESNGGYMARADIPDGETEESWFVKEVWRGIESRYPGDKLTDEVRARTEMELDVVRTKGYCGYYLVVADFINWAKDNGIRVGPGRGSGAGSIAAYALRITDLCPLTHGLIFERFLNPERPSMPDFDIDFDERRRSEVIRYVSNKYGEERVAMIATFGRLKSKAAIKDAARVMDYPFSHGERITKALPADIMGKGVTLKGLFDKNDKRYGDGGDFRKLHDEDADVRKIYQTALGLEGQIRQWGVHAAGVIMSSDPLIDIVPIMKREQDGAIITQFDYPMCEALGLVKMDFLGLRNLTVLDDALINIKRNRGIDLVLEDLDFEDQATYDLLARGDTLGVFQLDGGPMRALLRSMKPDKFEDISAVGALYRPGPMGADSHNKYARRKNGREPIDPIHPELEKPLETVLGETYGLIVYQEQVMEIAQVLAGFSLGQADNLRRAMGKKKKSELDKQYAGFQQGMLERGYSQKAITTLWDILLPFSDYAFNKAHSAAYGVISYWTAYLKANYPAEYMAALLTSTRVDKDKSAIYLNECRRMGIKVLPPDVNESVSNFASVGPDIRFGLGAIRNIGENVVAGIVEGRTTGGPYADFNDFLDKVPTLVCNKRVLDSLIKAGAFDSLGHRRRALTTVAEEGVDLYIDLKRQAAIGQDSLFGGGDDVFTGGRVEVPETMPEWEKTQLLAFERDMLGLYVSDHPLQGLEHVLRASSDSTIGDLLTNTDLPDGSTIRICGLITGVQRRMSKKGDPWASITIEDLEGGIEVMVFPGAYQLAMPVLVPDTIVVVKGRVRRKDEGIELNALEVTMPAMGSGGPERPLVVTLPVARCTADTIGTFKQVLSAHPGMSEVHLRLVGNGTTKVMRLDDSLRVAQSSSLIADLKELLGPHCLS
>NZ_CP045737.1|WP_153652400.1|1390205_1390613_-|DUF1801-domain-containing-protein
MAQHPDREKQTYTTVEDYIAAATYDVEPRLQEMRSVIRAALPDAEETISYNIPAYKQHGVVIVQFAGYDEHTSLNFFPTAGAFARFDEELKPYKTSKSAIRFPLDQPLPVQLIGDIARFRLEEAAQFAARKRSGG
>NZ_CP045737.1|WP_153652409.1|1400562_1401324_+|imidazole-glycerol-phosphate-synthase-subunit-HisF
MSLSVRVIPCLDVDNGRVVKGVNFVDLRDAGDPVEMAKVYDAEGADELTFLDITASSGNRSTTFDVVGRTADQVFIPLTVGGGVRTPDDVDRLLRAGADKVGINTAAIDRPEVIAEIAHRFGSQVLVLSVDARRSAEQPSGFEVTTHGGRRSAGIDAVEWARRATELGAGEVLLNSMDADGTKDGFDLEMIRAVRDVTQVPLIASGGAGRLEHFPEAIEAGADAVLAASVFHFGDLTIGQVKETLRAAGHRVR
>NZ_CP045737.1|WP_153654998.1|1401421_1403185_+|ATP-binding-cassette-domain-containing-protein
MTRRGFALLGRGIKEQRFLFWVSVIGSVLFGFMTVADARVLGWATDNVIRPSFARGDVAEGALVAAISLFMAVAILRALGIVARRLIGGIVYYRLVAEYRRRVTRQYISLPMSWHHRHPTGQLLSNANADVEGAWAVFMPLPMAIGVIAMLVAAIAEMVRADLVLTLVGLVVFPALFIINVFYQRWLSPKVAHAQSLRGSVSAVAHESFDGALVVKSLGRETDETDRFREVSHELRDANIAVGRIRSVFDPLLEALPNIGILMVIVLGVGRVASGAADPGDVVAVAYLFTVVAFPVRAIGWVLGELPRSVVSWERVEAVLQERGSMPYGTQTLAGNGPVRLDVEDLTFRFDDADRDVLRHISFDVQPGRVVAVVGATGSGKSTLTSLLTRLVDPQGGRIAVDGVDIRELTHDELARVIAVVPQGTFLFDDSVRENITLGADYSDDEVWAALRTVQAADFVAALPRGLDSELGERGTTLSGGQRQRLSLARALVRHPRLLVMDDATSAVDPEVEQRILKALAAHTSDGEGPTVLVVAYRKATIALADEVVFLDEGAIAARGSHDELVEASPDYRNLVNAYDQAREAQS
>NZ_CP045737.1|WP_153652410.1|1403181_1405020_+|ATP-binding-cassette-domain-containing-protein
MSTVDDLPEIESSRLSGTAIIRRGLALSPAIKDGLGFTIVLAILSTVGGSVIPILIQRTVDSGLGDGADTGVGDIAGFLTIAAILVLSTAAVAYWMRIRLFKASETGLAQMRVDAFRHVHDLSMLTQNSERRGVLVSRVTSDIDQVSQFLQFTGIQIVVSLGQILVATAIMAYYSWQLTIVVLVCFLPLAISLKWFAQRLSDAYDIVRRTVGEMIAVIAEPVVGASVVRAYAIEKRTQDRVDEGIKGNLDANVKAQKLVAVTFAASGVAGGLAIGAVVAFGVILGVAGDLSMGTVIAFAFLVGLFVGPVQTATQVLTDAQNAIASWRRVIDLLDTPADVVDPGPAGRPLPGGSLSARFDGVTFAYPGGPPVLTGVDIEIAPRQRVAVVGETGSGKTTFAKLLTRLMDPTEGVVSLGTSGGTWQDISDVSFADLRRHVLMVPQEGFLFDATLRENLLYGRQDASDRELVAVIDELELTDWFAGLPHGLDTQVGQRGESLSAGERQLVALVRSALADPQLIVLDEATSAVDPQTELRATRALDKLLDGRSSVTIAHRLSTAENADRVLVFDAGRLVEDGSHAELVDAGGVYARLHASWVAQASISGSQAVTEPS
>NZ_CP045737.1|WP_153652411.1|1405016_1405382_+|phosphoribosyl-AMP-cyclohydrolase
MTSPETLGPVPSLDPAIADRLKRDADGLVPAVVQDATSRDVLMVGWMDDEALHRTLTTGRGTFWSRSRQSYWVKGETSGHVQHVREVRLDCDGDTLLVVVDQTGPACHTGDPTCFDADRLL
>NZ_CP045737.1|WP_153652412.1|1405285_1405960_+|hypothetical-protein
MRRRHPARRRGPDRSRLPHRRPHLLRRGPPAVTPRRLYGPVVLATLAAGGLAFFAAARTWADAKLSSEGLPPSTVGVSGTDAEPLVSALALVVVTAALAVLAAGPRLRRVVGALTMLVSVLAVVVAPPSGSDALDRALRKAAEESPSFTGPESIGDISSTPWYAVTVLAFVVAFLLGAATIRWAGAWPTMGRRYEAPAARAAGTEEVSDSDMWKAMDEGQDPTQ
>NZ_CP045737.1|WP_153652413.1|1406002_1406206_+|hypothetical-protein
MHGSSPAAWTGVILCLLGITIGGVALIPEPRWIMFWIGVGITLASGIVGWAMAAAGFGVDRAEHSHN
>NZ_CP045737.1|WP_153652414.1|1406247_1406943_+|RDD-family-protein
MTDYPQYPQYPGEDGPQGQPQQPPQPPNGPGQGQAPPPPPGYGQQPPAYGQPPAYGHAPGYGQPPTYGQPPQGYGPRPFASWGSRVGAYLLDGLIGAAVALVPLIAGFIVIAATGTERTDYAGNTTIEDANPLGYVLLILGYVAAFVFALWNYVFRQGRTGQSLGKKIVGIKVVKEQTGQPMGVGLALGRYLLNTILTTITCYINVLWPLWDDKKQALHDKVVSTVVVSAN
>NZ_CP045737.1|WP_153652415.1|1406946_1407372_+|DUF2752-domain-containing-protein
MAVPVPAAREPVHPLVAPAAVAAAGTAAAVLLHLRDPHDSGTYGFCPFLALTGQPCPGCGGLRAVNDLTRGDLVGALSSNALAVVLVAVLAVAWVLWVVRRSTGRRDRMIVLGKGSGAAVLGVLAVFTVVRMTPWGSWLAP
>NZ_CP045737.1|WP_153652416.1|1407459_1408269_+|indole-3-glycerol-phosphate-synthase-TrpC
MSVLDEILVGVAEDLETRMAATSLEDLKQQASRQPPALDPMPAFRSDGVSVIAEVKRSSPSEGRLATIKDPAALATDYAAGGAAAISVLTEERRFGGTLADLRAVRGTVDVPLLRKDFITTSYQLWEARAAGADMALLIVAALEQIALESLIERARSIGLTPLVEVNDEAEVKRAVDAGADLIGVNARNLKTLEVDRGTFERLAPLIPDTAVKVAASGVRGPRDVIDYAKSGANVVLVGETLVRGDDPRASVADLVAAGVHPALQQHRW
>NZ_CP045737.1|WP_153652417.1|1408337_1409564_+|tryptophan-synthase-subunit-beta
MTYAQPDTTGHFGRFGGRFMPEALIAPLDELDRAWTEAKADPAFMTELDRMLREYANVPSPLYEAHRFSEAAGARILLKREDLNHTGAHKIRNVIGQALLAKRIGKPRAIAETGAGQHGVASATACAYLDLECTVYMGEVDTGRQALNVARMRMLGAEVIPVTSGSRTLKDAINEALRDWVASVDTTSYLFGTAAGPHPFPSMVRDLTRGIGDEARRQVLALDGKLPDAAVACVGGGSNAIGLFTAFIDDADVRLVGIEAGGDGVESGRHAATITGGDVGVLHGARSFLLQDEDGQTVESHSISAGLDYPGVGPEHSFLADTGRASYVPATDAAAMSAFDLLCKTEGIIPAIESAHALAGALDLAKELGPDATILVNLSGRGDKDVHTAAEYFGLIDEPVVLEQGVEE

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP045737_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045737_7

1462816-1462917

Orphan

Consensus_repeat	Method
GCCAAGAAGACCGCGGCCAAGAAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045737_7

>merge|NZ_CP045737|7|1462816-1462917|CRISPRCasFinder
GCCAAGAAGACCGCGGCCAAGAAGACCACATCCCCTGCGAAAACAGAAACGACCGTGACCAAGACTTCATCGAGCCCCGCCAAGAAGACCGCAGCCAAGAAG

>NZ_CP045737|7|7|1462816-1462917|CRISPRCasFinder
GCCAAGAAGACCGCGGCCAAGAAG	ACCACATCCCCTGCGAAAACAGAAACGACCGTGACCAAGACTTCATCGAGCCCC
GCCAAGAAGACCGCAGCCAAGAAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045737.1\|WP_153652444.1\|1449321_1450572_+\|M18-family-aminopeptidase	unknown	unknown	gnl\|CDD\|235073
NZ_CP045737.1\|WP_153652460.1\|1472864_1473620_-\|LppX_LprAFG-lipoprotein	unknown	unknown	gnl\|CDD\|319988
NZ_CP045737.1\|WP_153652455.1\|1465961_1466228_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045737.1\|WP_153652449.1\|1456536_1458675_-\|prolyl-oligopeptidase-family-serine-peptidase	unknown	unknown	gnl\|CDD\|224684
NZ_CP045737.1\|WP_153652451.1\|1460102_1461083_+\|DUF4192-family-protein	unknown	unknown	gnl\|CDD\|379390
NZ_CP045737.1\|WP_153655003.1\|1452310_1453609_-\|AMP-binding-protein	unknown	unknown	gnl\|CDD\|236215
NZ_CP045737.1\|WP_153652459.1\|1471111_1472857_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|341045
NZ_CP045737.1\|WP_153652458.1\|1470587_1471082_-\|carbonic-anhydrase	unknown	unknown	gnl\|CDD\|239474
NZ_CP045737.1\|WP_153652446.1\|1453780_1454713_+\|SH3-domain-containing-protein	unknown	unknown	gnl\|CDD\|377965
NZ_CP045737.1\|WP_153652456.1\|1466358_1468455_+\|DNA-gyrase-subunit-B	unknown	unknown	gnl\|CDD\|235501
NZ_CP045737.1\|WP_153652454.1\|1464373_1465897_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|197269
NZ_CP045737.1\|WP_153652462.1\|1476153_1478856_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|131764
NZ_CP045737.1\|WP_153652452.1\|1461126_1462605_+\|glutamate--cysteine-ligase	unknown	unknown	gnl\|CDD\|237408
NZ_CP045737.1\|WP_153652448.1\|1455327_1456305_-\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|235640
NZ_CP045737.1\|WP_153652457.1\|1468464_1470588_-\|acyltransferase-family-protein	unknown	unknown	gnl\|CDD\|224748
NZ_CP045737.1\|WP_153652461.1\|1473573_1476063_-\|DNA-topoisomerase-4-subunit-A	unknown	unknown	gnl\|CDD\|235503
NZ_CP045737.1\|WP_153652463.1\|1478855_1479422_+\|phosphodiesterase	unknown	unknown	unknown
NZ_CP045737.1\|WP_153652450.1\|1458671_1459979_-\|DNA-polymerase-IV	unknown	unknown	gnl\|CDD\|235118
NZ_CP045737.1\|WP_153652445.1\|1450780_1452244_+\|30S-ribosomal-protein-S1	unknown	unknown	gnl\|CDD\|236126
NZ_CP045737.1\|WP_153652447.1\|1454722_1455331_+\|dephospho-CoA-kinase	unknown	unknown	gnl\|CDD\|234620

Protein	Function_ID	Function_description	E-value
NZ_CP045737.1\|WP_153652444.1\|1449321_1450572_+\|M18-family-aminopeptidase	gnl\|CDD\|235073	PRK02813, PRK02813, putative aminopeptidase 2; Provisional.	0
NZ_CP045737.1\|WP_153652460.1\|1472864_1473620_-\|LppX_LprAFG-lipoprotein	gnl\|CDD\|319988	cd16334, LppX-like, family includes lipoproteins LppX, LprA, LprF and LprG from Mycobacterium tuberculosis. This family includes the homologous lipoproteins LppX, LprA, LprF and LprG from Mycobacterium tuberculosis (Mtb), all of which share a core fold with lipoprotein transporter proteins LolA and LolB. Mtb contains components such as glycolipids, lipoglycans and lipoproteins that play critical roles in regulating host responses and promoting survival of the pathogen. Mtb LprA is a lipoprotein agonist of Toll-like receptor 2 (TLR2) that regulates innate immunity and APC function. LprF, which is also found in Mycobacterium bovis but not in the nonpathogenic Mycobacterium smegmatis, has a central hydrophobic cavity that binds a diacylated glycolipid that it transfers from the plasma membrane to the cell wall, which might be related to the pathogenesis of the bacteria. Similarly, LprG functions as a carrier of glycolipids and lipoglycans, such as lipoarabinomannan (LAM), during their trafficking and delivery to the mycobacterial cell wall, contributing to virulence; LAM inhibits fusion of phagosomes with lysosomes as a means for mycobacteria to evade host defense. In addition, LprG has potent TLR2 agonist activity that modulates antigen processing of dendritic cells and macrophages. LppX is required for the translocation of the key virulence factors, the phthiocerol dimycocerosates (PDIMs), to the surface of Mtb.	4.52128e-27
NZ_CP045737.1\|WP_153652449.1\|1456536_1458675_-\|prolyl-oligopeptidase-family-serine-peptidase	gnl\|CDD\|224684	COG1770, PtrB, Protease II [Amino acid transport and metabolism].	0
NZ_CP045737.1\|WP_153652451.1\|1460102_1461083_+\|DUF4192-family-protein	gnl\|CDD\|379390	pfam13830, DUF4192, Domain of unknown function (DUF4192).	8.8447e-52
NZ_CP045737.1\|WP_153655003.1\|1452310_1453609_-\|AMP-binding-protein	gnl\|CDD\|236215	PRK08276, PRK08276, long-chain-fatty-acid--CoA ligase; Validated.	2.12657e-92
NZ_CP045737.1\|WP_153652459.1\|1471111_1472857_-\|MFS-transporter	gnl\|CDD\|341045	cd17502, MFS_Azr1_MDR_like, Saccharomyces cerevisiae Azole resistance protein 1 (Azr1p), and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of multidrug resistance (MDR) transporters including various Saccharomyces cerevisiae proteins such as azole resistance protein 1 (Azr1p), vacuolar basic amino acid transporter 1 (Vba1p), vacuolar basic amino acid transporter 5 (Vba5p), and Sge1p (also known as Nor1p, 10-N-nonyl acridine orange resistance protein, and crystal violet resistance protein). MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. This subfamily belongs to the Methylenomycin A resistance protein (also called MMR peptide) and similar multidrug resistance (MDR) transporters (MMR-like MDR transporter) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.34272e-27
NZ_CP045737.1\|WP_153652458.1\|1470587_1471082_-\|carbonic-anhydrase	gnl\|CDD\|239474	cd03379, beta_CA_cladeD, Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.	9.84921e-50
NZ_CP045737.1\|WP_153652446.1\|1453780_1454713_+\|SH3-domain-containing-protein	gnl\|CDD\|377965	pfam08239, SH3_3, Bacterial SH3 domain.	4.43823e-05
NZ_CP045737.1\|WP_153652456.1\|1466358_1468455_+\|DNA-gyrase-subunit-B	gnl\|CDD\|235501	PRK05559, PRK05559, DNA topoisomerase IV subunit B; Reviewed.	0
NZ_CP045737.1\|WP_153652454.1\|1464373_1465897_+\|hypothetical-protein	gnl\|CDD\|197269	cd09172, PLDc_Nuc_like_unchar1_1, Putative catalytic domain, repeat 1, of uncharacterized hypothetical proteins similar to Nuc, an endonuclease from Salmonella typhimurium. Putative catalytic domain, repeat 1, of uncharacterized hypothetical proteins, which show high sequence homology to the endonuclease from Salmonella typhimurium and vertebrate phospholipase D6. Nuc and PLD6 belong to the phospholipase D (PLD) superfamily. They contain a short conserved sequence motif, the HKD motif (H-x-K-x(4)-D, where x represents any amino acid residue), which characterizes the PLD superfamily and is essential for catalysis. Nuc and PLD6 utilize a two-step mechanism to cleave phosphodiester bonds: Upon substrate binding, the bond is first attacked by a histidine residue from one HKD motif to form a covalent phosphohistidine intermediate, which is then hydrolyzed by water with the aid of a second histidine residue from the other HKD motif in the opposite subunit. However, proteins in this subfamily have two HKD motifs in a single polypeptide chain.	1.26778e-08
NZ_CP045737.1\|WP_153652462.1\|1476153_1478856_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|131764	TIGR02717, Uncharacterized_protein_MJ0590, acetyl coenzyme A synthetase (ADP forming), alpha domain. Although technically reversible, it is believed that this group of ADP-dependent acetyl-CoA synthetases (ACS) act in the direction of acetate and ATP production in the organisms in which it has been characterized. In most species this protein exists as a fused alpha-beta domain polypeptide. In Pyrococcus and related species, however the domains exist as separate polypeptides. This model represents the alpha (N-terminal) domain. In Pyrococcus and related species there appears to have been the development of a paralogous family such that four other proteins are close relatives. In reference, one of these (along with its beta-domain partner) was characterized as ACS-II showing specificity for phenylacetyl-CoA. This model has been constructed to exclude these non-ACS-I paralogs. This may result in new, authentic ACS-I sequences falling below the trusted cutoff.	5.44731e-137
NZ_CP045737.1\|WP_153652452.1\|1461126_1462605_+\|glutamate--cysteine-ligase	gnl\|CDD\|237408	PRK13517, PRK13517, glutamate--cysteine ligase.	7.30964e-06
NZ_CP045737.1\|WP_153652448.1\|1455327_1456305_-\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|235640	PRK05901, PRK05901, RNA polymerase sigma factor; Provisional.	3.12195e-102
NZ_CP045737.1\|WP_153652457.1\|1468464_1470588_-\|acyltransferase-family-protein	gnl\|CDD\|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	1.27188e-71
NZ_CP045737.1\|WP_153652461.1\|1473573_1476063_-\|DNA-topoisomerase-4-subunit-A	gnl\|CDD\|235503	PRK05561, PRK05561, DNA topoisomerase 4 subunit A.	0
NZ_CP045737.1\|WP_153652450.1\|1458671_1459979_-\|DNA-polymerase-IV	gnl\|CDD\|235118	PRK03348, PRK03348, DNA polymerase IV; Provisional.	0
NZ_CP045737.1\|WP_153652445.1\|1450780_1452244_+\|30S-ribosomal-protein-S1	gnl\|CDD\|236126	PRK07899, rpsA, 30S ribosomal protein S1; Reviewed.	0
NZ_CP045737.1\|WP_153652447.1\|1454722_1455331_+\|dephospho-CoA-kinase	gnl\|CDD\|234620	PRK00081, coaE, dephospho-CoA kinase; Reviewed.	1.69754e-83

>NZ_CP045737.1|WP_153652452.1|1461126_1462605_+|glutamate--cysteine-ligase
MGQDVEAREFSREDRTLYRTKVRRCLDVFARMLGERDFSFEHPHVGIEIEFNLIDALGDPSLRNDDALAAIADPDFQTELGLFNIEINVAPTRIDGKGLDVLESALRDDLNAAQAKATSVDTNLLMIGILPTLQDGHLSREAISANPRYHLLSDQILSARGEDIEIVIDGVDRLDTTADTIIPEAACTSTQLHLQVEPDDFAPMWNAAQAIAGVQVAIGANSPFLLGQQLWHETRIALFEQATDTRSEELKTQGVRPRVFFGERWITSVFDLFEENVRYFPSLLPIVDEEDPLEELEAGRIPQLAELRLHNGTVYRWNRPIYDIADGRPHLRIENRLLPAGPTVVDTMANAALFYGLVTVLGTSERPVWSQLSFRAAEDNFHQAARAGIEADVYWPGVGTVAVRELALRQLLPLADTGLEQMGVDTAVRDRLLGIIEQRCITGRNGATWLIEEFAHRTRTSGDRAEAMRATTLAYEEHMHAGDPVHLWPTRG
>NZ_CP045737.1|WP_153652451.1|1460102_1461083_+|DUF4192-family-protein
MTHTPPVFTAHDVPDLINAVPTFFGFRVEESIVAVATSGPRRRLGFRLRMDLPRPGKEEAVARKVVGHLTDHGAEGAIVIVLTEQQELALELLDAIHAALDDFSGIELIVRARADGERYWTDEPGFPPEGLAYVTSEHHLSIVQAVAAGQQILPSRQVLVDRFRPVTGVRRRWLEHATASILEEIVPQVARTVPGELAATGMAVVEPILDRVRAGDQVSDGDLLRIAAWVSTISVRDEVWGLMTRDNAPEMLAALTLVSTRAVPPLEPAVLSLAAFAAWLTGDGAQALIAVDRAIEADPCYSMAGLILEILERGVSPASWVGWPTP
>NZ_CP045737.1|WP_153652450.1|1458671_1459979_-|DNA-polymerase-IV
MRSTASIMHLDLDAFFASVEQRDKPSLRGRPVIVGGTGQRGVVATASYEARVHGVRSAMRTAEARARCPHAAFLGGRFEAYREASRLVMARLREESELIEPLSLDEAFVDLAAGEGFDPDRVEEVVDKIRTDITHITGGLTASVGVASSKLMAKIASEINKPDGVFVVEPGTEADVLGPMQVNAIPGVGPATAERLRRVGILTVEDLRTPSEDELVRLLGQASGRSLHRLARAEDDRPVVATREAKSVSVEDTFERDISDRLQLETIIERMARGVSARLRKSGLSGRTVTLKMRHHDFETHTRSSTLAHPTDSARVLATTARGLLAGEDISNGLRLLGVGVSGLADWVQDDLFAEDDPEPEDEDDTTEDDTASPTRWYPGMDVHHADLGDGWVWGAGLGRVTVRFETRWTPPGPVRTFRADDPALGAGHSGTLQA
>NZ_CP045737.1|WP_153652449.1|1456536_1458675_-|prolyl-oligopeptidase-family-serine-peptidase
MTSPVLPEPTASLPAPPVAERRPITRSHHGDDFVDDYEWMRDKEDPATLAYLEAENAYTDAATAHLEPLRQQIFDEIKARTLETDLSVPTRHGAWWYYARTIEGQQYAIRCRCAVQDPDDWTPPVLDAGSEIPGEEILLDSNVEAEGHEFFSLGAFSISDDENFLAWSVDTQGDERYTIRIKDLRTGEILPDEITGASGGATWSAGGTHLFYTTVDDAWRPYRVWRHQVGTTGDDALVLEETDERYFIGVGRTHSERYLVIGLGSKITSEYRVLEADDPEGEFRVVLPRREGVEYSLEHAVIQGEDRFVILHNDGALNFELVTVPVDDPTDRTVVIPGSDTVRLEDVDVFARHLVVSFRSGALARVGTISIGPDGLGELSEIDFGEELFTSGVGANAEWDPPLIRVGVGSFVTPSSVYDFDPETRELILRKQAPVLGGYDPADYEQHRSWATADDGTLVPVSIVCRKDTPRDGTAPALLYGYGSYEASMDPGFSVMRLSLLDRGFVFAIAHVRGGGELGRHWYDDGKQLHKRNTFTDFVASARHLVAEGWTSADRLIAEGGSAGGLLMGAVANLAPDAFAGIVAAVPFVDALTTILDPSLPLTVIEWDEWGNPLDDPEVYAYMKSYTPYENVGAHDYPAILAVTSLHDTRVMYVEPAKWVARLRATATGDAPILLKTEMHAGHGGVSGRYASWKERAWELAWIIDVATRHAR
>NZ_CP045737.1|WP_153652448.1|1455327_1456305_-|sigma-70-family-RNA-polymerase-sigma-factor
MYKQLNGSRTVSTRTGNTTAEGKDSVGMYLAEIARTPLLDAEREVELSKTVEAGLFARHLLEEGRVGRKKGGAPKWATEEELTWLAEEGDRAIQEFIQANLRLVVSIARKYGRSAMPMLDLVQEGNTGLIRAVEKFDYAKGFKFSTYATWWVRQAITRGIAQQARVVRLPVHVVEELNQVTAARRNLERQLGYDPEPAEIALELGMDVERVVDLMAWGRDHVSLDSPVDEDGDTSLGDLIARETQPGPDFAVLDDETRHLIATLVDHLGPREADIVRARYGLLDGRQQKLADIGKRHGISAERVRQLEREALATLRRIADPDLAA
>NZ_CP045737.1|WP_153652447.1|1454722_1455331_+|dephospho-CoA-kinase
MLKVGLTGGIGSGKSTVSALLAAHGAVVIDYDQLARDVVEPGSPALDEIAARFGADVIAEDGTLDRPALGAKVFADPAELQALNGITHPAIGRLADERQAAAGPDAIVVHDNPLLVEMGAAGLCDVVVVVDVPVDVQVERLTTQRGMTEADARARIAAQASREERTGAADLVIDNTGPQDELALIVGGTWDELVSRAAARAV
>NZ_CP045737.1|WP_153652446.1|1453780_1454713_+|SH3-domain-containing-protein
MADSRHKHAAPRPARRTLRTSRSARAAVLPLAGLLAIGGVVGVAAAQEGGSPAAEAGATIPQQPPKKDVFAASVSSGQAPATVSRSAERPPLPNAAAVEDKIKGELYAKSDLDIHAAAKKSSPVLAEVESGDTVEVTGKRSDGWAEIMHKGLPRWVDASSITTQKPVEETSPETSDDEAPEAATSGGLSTAPCAAGSGPESGLQPDTIKVYRAVCAKFPSIVSYGGVAGRGEHGTGQALDIMISSDLGNQVAAFLQQNRTALGVDYLIWRQRIWRPATSPDWRGMSDRGSPTANHMDHVHVTTYGNAATG
>NZ_CP045737.1|WP_153655003.1|1452310_1453609_-|AMP-binding-protein
MTATASEQQQRRVAGALAARGLVAGDRVVLSVPGSTAYVSAVLGATRSGVVPVPLDPRLTAYERDRIVADVSPALMIDDEAALEALLTGPAGVLDPAPRCRPMHFTSGTTGRPKGVWSGLLSPEDAAALVREERDLWGFCQEDLDLVVSPIYHSAPLRFAMGTILAGGSVAVLPAFEPAAFLEAVAALRPTSMFCVPAHLQRLLSHLDEHHVRPDLSSFRLVAHAGAPCPEPVRRRTHALFGLDTVWEFYGSTEGQFTACPAAEWVERPGTLGRARPGRVVSVDEDDQLWCAVPPWARFTYWNAPEKTAATWRDTPDGPAFSVGDLGRVEDGHVYLDSRREDLIISGGVNVYPAEVEGALQDAPGLVDVAVFGRDDERWGQQVCAAYVGAVDEQVLRELARTRLAPPKRPKTYERVDVLPRTATGKVRRTEL
>NZ_CP045737.1|WP_153652445.1|1450780_1452244_+|30S-ribosomal-protein-S1
MTSSIAHVAPQVAINDIGSEEDFLAAIDATIKYFNDGDIVEGIIVKVDRDEVLLDIGYKTEGVIPSRELSIKHDVDPNEVVSVGDSVEALVLQKEDKEGRLILSKKRAQYERAWGDIEKIKAEDGVVEGTVIEVVKGGLIMDIGLRGFLPASLVEMRRVRDLDPYIGQKIEAKIIELDKNRNNVVLSRRAWLEQTQSAVRQNFLTELQKGQVRKGVISSIVNFGAFVDLGGVDGLVHVSELSWKHIDHPNEVVQVGDEVTVEVLDVDMDRERVSLSLKATQEDPWQHFARTHQIGQIVPGKATKLVPFGAFVRVEEGIEGLVHISELAERHVEIPEQVVQIGDSVMVKIIDIDLERRRISLSLKQANETEASATDDFDPTLYGMTSSYDEQGNYIYPEGFDPETGEWQEGFDEARAAWEKQYAEAHERWEAHKKQIQEAEKAGIEAAAASNYSSDSSAGSEDAPQEGSLASDEALQALREKLTGGEA
>NZ_CP045737.1|WP_153652444.1|1449321_1450572_+|M18-family-aminopeptidase
MTIAPAADLCDFIDRSPTPFHVCRTVASELAAAGYEELREADEWPQQPGRYLVVRGGSLVAWSTEAESSPQDAFRVVGGHTDSPNLRVKQHHDLDQEGLGVVALHPYGGAWLNSWLDRDLGVAGRLVLRDGSERLVHVDEPVIRVPQLAIHLSADRKIDLDPQRHLNGIWSTSPGTFLDLVADRAAVSREDILGFELMTHDTAPSRLTVNGELVSAPRLDNQTTCFTGTRALLAATPVPGVRPVLALFDHEEVGSTSERGAQSDLLITVLERIVLTAGGTREDFHRAIAASVCASGDMAHATHPSHAERHEPLHHVEIGGGPVLKVHPNLRYATDAVGTAHFARACEQAGVPLQRYEHRADLPCGSTIGPLSAARTGMLTVDVGAPQLAMHSAREVMGAADVDPYAAALAAFLSPA
>NZ_CP045737.1|WP_153652454.1|1464373_1465897_+|hypothetical-protein
MSLLLGFGSVASNAENVTEEPAAAATPTAAPTTPAPTATEEPAAPDATTTPPPKVRAAAASPYGSNYPVTLETNFSRPFKAISSSANSDFSLLNDLERLIRGSYKDPRTGKLRPASVRRSNSVFMSISRMENSHRVGRELIRAAKAGVKVRVIHGKASQSKESRALQRALKKGSLRDSNFKICQKGKSLACLSGLNGAIMHSKILLVSNTFTRDNKPAKAAIWSGSANLGGPSGERTYNNGLTIYNDKKLWYGTRQMWDDMYAERNVGNNYLRYIDKHASRYGISESERKKFGYTKADPVNGMFYSNLANVTIYATPILATPTNGKDPVLNLLNRVVPDDQCRIRLQENRFKYRRIAVAQKLVQLADQGCKVSGVYFEDDLKVNRVAHCQLHIRICRPILDVFKTSSRRIEAAWAKPHDKTILVEAKLKKNRLNPEEVAIDGTKPSSWPSDGIRTKLVQAGSAALTGSNLVVSDEITTETTDPAVYEDYLQHWKSILKSNEIHSYPY
>NZ_CP045737.1|WP_153652455.1|1465961_1466228_-|hypothetical-protein
MLIQSDPHRLREKVTVTTLTAPKLSSLDRCDRCGAQAYVRVTLGGGGELLFCAHHARQHEEKLREMSAEIHDESERLASSSTTVVDED
>NZ_CP045737.1|WP_153652456.1|1466358_1468455_+|DNA-gyrase-subunit-B
MSLQHTSSREALIIDNTYDARNLLVLEGLEAVRKRPGMYVGSTDTRGLMHCLWEIIDNSVDEALGGHGSHILVALHADGSVEVQDQGRGVPVDIEKKTGLTGVEVVYTKLHAGGKFGGGSYVATGGLHGVGASVVNALSSRLDVEVDKGGATWAMSFRRGVPGVFAGDGPDVDFTPTNELRKIGKVAKARTGTRVRYWADPQIFIKGAKFAYDELVARARQTSFLVPGLELVIRDERGEVPSEEKFRHDGGISEFCEFLAPDEPVSDVLRLQGEDVFTETVPLLDDKGHMTPQDIERNLGVDVALRWGTGYDTELKSFVNIIATPKGGTHVNGFERALTKTFNDVLKTTRLLKSGDPDVIKDDALEGMTAVVTVRLAEPQFEGQTKEVLGTPAVTKIVNQVVSRELKAFLTSSKAAEKAKARLVMQKVVDASRTRLAARQQRDTQRRKNALESSALPAKLADCRSNDVERSELFIVEGDSALGTAKSARDSEFQALLPIRGKILNVQKASIGDMLKNAECSSIIQVVGAGSGRTFDVDAARYGRIIFMADADSDGAHIRCLLATLFFRYMRELVDAGRVYTAVPPLHRIELTNPKKGQEKYVYTYSDPELQRTMAELKRKGIKWKDPVQRYKGLGEMDASQLAETTMDPRHRTLRRLTVDDGEEAAEVFELLMGNEVPPRKEFIVQGAYEIDADKIDA
>NZ_CP045737.1|WP_153652457.1|1468464_1470588_-|acyltransferase-family-protein
MPVPSAPADAPATQRTPRPVRPEIQALRAGAALLVVLYHLWPGRLPGGFMGVDVFFVISGFLITAHLAREAETTGRIRLGRFWARRARRLLPAAYLVLATSALAVYLWMPLLNWGQNFREILASALYFQNWRLAFDAVDYLAAENAPSVAQHYWTLSVEEQFYVAWPLIVLASILLAARIGARRLTTVTVVVAAVTVASFAYSWWLTYDNVSFAYFSTFTRAWEFGAGALLALLTLRAAPGRRRTHPVTPHVAALVSWAGIAVLVYCGLELTGSTPFPGTAALLPVLATVAVIAAGMPDSRLSPRWIIERRFVQWTGDISYPLYLWHWPPIVLLPVILGHELGFWPRVGILVATFAAAALTKRYVEDPVRTGRKLGIQRSTVTFAFTSVAAACLAAACLGGVQHANAEADRAEQLKENITKDTPRCFGAASMDPDQPCDNPELDGLLVPDTTAIRRDNPNYPGCQTSDNEVRTTCTFGDPKDPTLPHVVVIGDSHARALLPAFVPMAKEGKLFLEVQVKAGCNWSSNPHPNPDRTIAEGCYEWRDNVNAYLLKNADDIDLIVTGALAHPRPATGPKEQVAGFATTWRPLAERGVPIVAFRDNTAQPVDTNDCLALEGTITPDSCALPRDKAFPNFDPLVGAAKEVKGARLYDFTRFYCDDEKCPAVIGGVNVYRDRTHVSKTYMATMKPYIEQRLDEDGLLAARRDG
>NZ_CP045737.1|WP_153652458.1|1470587_1471082_-|carbonic-anhydrase
MRDFDDLLEANTSYANSFDLSGFDGIARAGVAMVTCMDSRIDPLRMIGLKPGDAKILRNPGGRVTDQALVALVLGVNLLQVERILIVEHTRCAMASSTEDELKARIADSAGTDASWMTLGAIVDQRNTVKADVMRVRSHPLIREDVAVGGFVYDVDTGLLERVD
>NZ_CP045737.1|WP_153652459.1|1471111_1472857_-|MFS-transporter
MTQPPAIRPASKVLLALAAVAIAFAAADTYVVVLALPDMMSTVGLNLDDLQRAAPIVSGFLLGYVGVLPLIGRISDLRGRVPVLLGSLVVFAVGSVVTAAAYDLETVVAGRLIQGIGGGGLIPPTLALVADLWPPHRRGMPLGVVGAVQELGSVLGPLYGAAVLAFGDWRTIFWLNCAIGLVLAAAMVPLRDAVHDATAGKRLDILGAVLGVLALTGVALVMLAPTRLVQDVEIGRAYLPVTGDSRWLTPLALATFAVIALFLLRLATARHPLVAWRGWPALARETDIWGALLLTTGLGAVIVTFASAEPESGAVSPDAPWLLPIAVAAFIGFAIRQRRAPQPLIPRGALSSRPSWGALVVSFFVGASLIAALVDIPFFARLTVHRDSQLDAALVLVRFLVALPVGALIGGWLLRRVPAHVLTAVAMLMSAVAFWHMTTWGRTSLDHPVETWSLVLGGLGFGLAIAPVNAALLAHTADAVHGVASALLIVARMVGMLLGISALTTIGLRAFYSATEKIPPAAQLCNGEARLCQAYKDAQIDAGITQLHAVFVGAAGCAALAAVLALVLLRPAATSPAEPAA
>NZ_CP045737.1|WP_153652460.1|1472864_1473620_-|LppX_LprAFG-lipoprotein
MSAMSPIRRTPPWETERVRTRHLLPVLLATLLALTGCTGGSDSSEPKGGDTDKLQARLDTAKKTLDTAETINIALATKRLPDGITGLLSATGKGNHSPAFTGKVNVVTGGSSLGADVVAVDGKVWAKTGFLPDFTVIDPQDLKAPDPAALVSADKGISQILVKTTKLRDAGQSRDGKDVLTTIKGTLPGDVVATIIPSATADQEFQVTYRLDDDDELRDATLSGAFYPGGGTVTYTVSLSTSDTPVSITKP
>NZ_CP045737.1|WP_153652461.1|1473573_1476063_-|DNA-topoisomerase-4-subunit-A
MARTSKQAPEEEFEEHILDTDVGDEMRSSFLEYAYSVIYSRALPDARDGLKPVQRRLLFTMDDMGLRSDRGHVKSARPVGEVMGRLHPHGDSAIYDALVRLVQPWSLRLPLADGHGNFGSPDDPPAAMRYTEIRMDAAAEAMTASINEDTVDFRPNYDGRELEPVVLPAALPNLLVNGASGIAVGMATNIAPHNLIEVVQALRHLIKHPKADLDDLMRFIPGPDLPTGGKIVGLEGVRDAYATGNGSFRMRASARIENVTPRKKGIVITELPYNVGPEKVIEAIKKLVQAKKLQGISDLKNLTDRHKGLQLVIEIKNGYIPETILEQLYKSTPMESSFGINAVALVDGQPRTLGLKQMLEVYLEHRIDVVRRRTTFRRGKAADRLHLLEGMLLALLDIDEVIQLVRSSENRGEAKERLMSVFDLSDPQATYILDLTLGRLTRYDRIEVEKEIEELRRTIEQLDAILGDESLLRTVVGDELNEMAQTFGTPRRTVLLESSGQTATAASPLEVADDPCWVLLSATGLLARTSDDSPLGAVDRRVKHDTIVSAVRTTARGEVGVITAAGTVHRISVLELPGLPPSAHSPNLQGGLPLSEVAELDSAALALMTFDEDGPGIALGTRQGVVKRVRPDHLSRDQWELISLADGDAVVGAAVLESGEEQLAFVTSDAQLLYFSASLVRPQGRSGGGVAGIKLAAGQRVVSFGAVADVDDAYVVTVAGSASALPGTQNGAVKVSPLSIYPPKGRATGGVRCQRLLKGEDGLLLAWVGDGTPMACATSGSAVDLPPVSDRRDGSGVPVAQPILAVAGPPAARIDVSDVTDSPDPAVGD
>NZ_CP045737.1|WP_153652462.1|1476153_1478856_+|GNAT-family-N-acetyltransferase
MGPVTNEVHPVEHWEADVLLRDGRVAQLRPILEADADRFVEFYSRVSEESKYFRFFAPYPTLSDKDVKRFTIVDHDRRVAFVVTLHSEIIGVGRYDAVSDDEAEVAFLVEDAHQGRGVGQLLLEHLAQAGRERGIRRFVADVLPSNARMQQIFREMGYKIEGMIEDGVQRLIFETEPTDMAIGVMRAREQRAEAASIERIFKARSIAVIGASRRQDSIGQAMVRNLVLGDFLGSVYAVNSQAEAVSGLPAYKRVQDIPGEVDVAIVAVPAESVNDVVLDCAAKGVHGLIVISAGFAEEGPEGRQRQRALLGLSRSYGLRLVGPNCLGLINTAPDLQLNASLSPAMPPQGRVGFFCQSGALGTAILESVSRRGLGLSTFVSAGNRADVSGNDLLQYWQEDDATEVILLYLESIGNPRKFSRIARRVSRTKPIVAVKSGRSTQGVPVGHTVARTSAPQSAVDAMFRQAGVIQVDTLDEMFDVAQLLAHQPLPRGNRISIVGNSDAVALIVADAAAAAGLRVAEPVSLGANANADDFEVAIETAIANPDVDALVAVYIPPLNTSGEEVANVLAAVGEQSDKPIVSTFLGTEGVPVLLRVPDLLGGSAGRGSVPSYAAPESAVRALARVVNYAEWAARDHGEFHLAMDHRSGDARALVRDVLKAAPRGAVLSTDQVHTLLACYGIDLLTWINVHDRDEAIAAGEKLGWDVVLKAGSEHLRSRPDIDHVWRGIRDAEEMAEAWDELSGWTGMRKDTKFFVQRVAPDGVHVSFGVTEDPLFGPLVSFGLAGAPSELLGDRSYGIPPLTDLDAEAMIRDLRSAPLLYGYRGSEKVDVDALQDIIVRLAAMKDDLPEIAELDLEPVAVHPHGFTALSARAKVMPTADRRGEWYVRRLSQPAAAGDTLT
>NZ_CP045737.1|WP_153652463.1|1478855_1479422_+|phosphodiesterase
MTTDHTRALFDEVSRSGYYPEIVAEGLRDALADELVRGFVLHHEPTFDRDEIRRHMTVLALTPSRLVLVHTDEHPGDDLLPKPYTSTTSEAVALDQVRSVVVTRMVTSNSKQLEEALLTIGWGAVSRVELEPARCSDPECEADHGYSGSLTGDDFSLRLAAAGDGGAAVERLLAFARTLSAATAGRSS

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP045737_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045737_8

1525185-1525279

Orphan

Consensus_repeat	Method
GGCAGCCACGGCTACCCGAAGCCCTCATCGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045737_8

>merge|NZ_CP045737|8|1525185-1525279|CRISPRCasFinder
GGCAGCCACGGCTACCCGAAGCCCTCATCGTGCTTCCCGGGGCGGACGGACGATGAGGGTTTCAGGCAGCCACGGCTACCCGAAGCCCTCATCGT

>NZ_CP045737|8|8|1525185-1525279|CRISPRCasFinder
GGCAGCCACGGCTACCCGAAGCCCTCATCGT	GCTTCCCGGGGCGGACGGACGATGAGGGTTTCA
GGCAGCCACGGCTACCCGAAGCCCTCATCGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045737.1\|WP_153652507.1\|1531091_1531640_+\|formimidoyltetrahydrofolate-cyclodeaminase	unknown	unknown	gnl\|CDD\|377428
NZ_CP045737.1\|WP_153655005.1\|1517326_1518805_-\|glutamine-synthetase	unknown	unknown	gnl\|CDD\|223252
NZ_CP045737.1\|WP_153652509.1\|1533356_1533752_+\|RNA-methyltransferase	unknown	unknown	gnl\|CDD\|377438
NZ_CP045737.1\|WP_153652500.1\|1522977_1523628_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045737.1\|WP_153652510.1\|1533675_1534605_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045737.1\|WP_153652493.1\|1514206_1515550_-\|NADP-specific-glutamate-dehydrogenase	unknown	unknown	gnl\|CDD\|181834
NZ_CP045737.1\|WP_153652505.1\|1529388_1530075_-\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|187585
NZ_CP045737.1\|WP_153652495.1\|1516420_1517308_-\|class-A-beta-lactamase	unknown	unknown	gnl\|CDD\|185339
NZ_CP045737.1\|WP_153652508.1\|1531640_1533320_+\|formate--tetrahydrofolate-ligase	unknown	unknown	gnl\|CDD\|376511
NZ_CP045737.1\|WP_153652501.1\|1523909_1525142_+\|alpha/beta-hydrolase-fold-domain-containing-protein	unknown	unknown	gnl\|CDD\|224423
NZ_CP045737.1\|WP_153652497.1\|1519940_1520720_+\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|369777
NZ_CP045737.1\|WP_153652496.1\|1518930_1519944_+\|methylenetetrahydrofolate-reductase	unknown	unknown	gnl\|CDD\|238299
NZ_CP045737.1\|WP_153652503.1\|1526885_1527260_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226318
NZ_CP045737.1\|WP_153655006.1\|1527322_1528513_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|227277
NZ_CP045737.1\|WP_153652502.1\|1525321_1526782_+\|YdiU-family-protein	unknown	unknown	gnl\|CDD\|234583
NZ_CP045737.1\|WP_153652499.1\|1522286_1522610_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377177
NZ_CP045737.1\|WP_153652504.1\|1528528_1529356_-\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|273884
NZ_CP045737.1\|WP_153652498.1\|1520799_1521984_-\|DUF222-domain-containing-protein	unknown	unknown	gnl\|CDD\|367155
NZ_CP045737.1\|WP_153652494.1\|1515691_1516387_-\|ANTAR-domain-containing-protein	unknown	unknown	gnl\|CDD\|379056
NZ_CP045737.1\|WP_153652506.1\|1530212_1531082_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|375319

Protein	Function_ID	Function_description	E-value
NZ_CP045737.1\|WP_153652507.1\|1531091_1531640_+\|formimidoyltetrahydrofolate-cyclodeaminase	gnl\|CDD\|377428	pfam04961, FTCD_C, Formiminotransferase-cyclodeaminase. Members of this family are thought to be Formiminotransferase- cyclodeaminase enzymes EC:4.3.1.4. This domain is found in the C-terminus of the bifunctional animal members of the family.	8.66682e-29
NZ_CP045737.1\|WP_153655005.1\|1517326_1518805_-\|glutamine-synthetase	gnl\|CDD\|223252	COG0174, GlnA, Glutamine synthetase [Amino acid transport and metabolism].	2.31735e-73
NZ_CP045737.1\|WP_153652509.1\|1533356_1533752_+\|RNA-methyltransferase	gnl\|CDD\|377438	pfam04993, TfoX_N, TfoX N-terminal domain. TfoX may play a key role in the development of genetic competence by regulating the expression of late competence-specific genes. This family corresponds to the N-terminal presumed domain of TfoX. The domain is found as an isolated domain in some proteins suggesting this is an autonomous domain.	2.36364e-05
NZ_CP045737.1\|WP_153652493.1\|1514206_1515550_-\|NADP-specific-glutamate-dehydrogenase	gnl\|CDD\|181834	PRK09414, PRK09414, NADP-specific glutamate dehydrogenase.	0
NZ_CP045737.1\|WP_153652505.1\|1529388_1530075_-\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|187585	cd05324, carb_red_PTCR-like_SDR_c, Porcine testicular carbonyl reductase (PTCR)-like, classical (c) SDRs. PTCR is a classical SDR which catalyzes the NADPH-dependent reduction of ketones on steroids and prostaglandins. Unlike most SDRs, PTCR functions as a monomer. This subgroup also includes human carbonyl reductase 1 (CBR1) and CBR3. CBR1 is an NADPH-dependent SDR with broad substrate specificity and may be responsible for the in vivo reduction of quinones, prostaglandins, and other carbonyl-containing compounds. In addition it includes poppy NADPH-dependent salutaridine reductase which catalyzes the stereospecific reduction of salutaridine to 7(S)-salutaridinol in the biosynthesis of morphine, and Arabidopsis SDR1,a menthone reductase, which catalyzes the reduction of menthone to neomenthol, a compound with antimicrobial activity; SDR1 can also carry out neomenthol oxidation. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	3.89706e-70
NZ_CP045737.1\|WP_153652495.1\|1516420_1517308_-\|class-A-beta-lactamase	gnl\|CDD\|185339	PRK15442, PRK15442, beta-lactamase TEM; Provisional.	1.29129e-56
NZ_CP045737.1\|WP_153652508.1\|1531640_1533320_+\|formate--tetrahydrofolate-ligase	gnl\|CDD\|376511	pfam01268, FTHFS, Formate--tetrahydrofolate ligase.	0
NZ_CP045737.1\|WP_153652501.1\|1523909_1525142_+\|alpha/beta-hydrolase-fold-domain-containing-protein	gnl\|CDD\|224423	COG1506, DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism].	6.68604e-08
NZ_CP045737.1\|WP_153652497.1\|1519940_1520720_+\|methyltransferase-domain-containing-protein	gnl\|CDD\|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	4.15657e-13
NZ_CP045737.1\|WP_153652496.1\|1518930_1519944_+\|methylenetetrahydrofolate-reductase	gnl\|CDD\|238299	cd00537, MTHFR, Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase to convert homocysteine to methionine. The enzymatic mechanism is a ping-pong bi-bi mechanism, in which NAD(P)+ release precedes the binding of methylenetetrahydrofolate and the acceptor is free FAD. The family includes the 5,10-methylenetetrahydrofolate reductase EC:1.7.99.5 from prokaryotes and methylenetetrahydrofolate reductase EC: 1.5.1.20 from eukaryotes. The bacterial enzyme is a homotetramer and NADH is the preferred reductant while the eukaryotic enzyme is a homodimer and NADPH is the preferred reductant. In humans, there are several clinically significant mutations in MTHFR that result in hyperhomocysteinemia, which is a risk factor for the development of cardiovascular disease.	9.03645e-17
NZ_CP045737.1\|WP_153652503.1\|1526885_1527260_+\|hypothetical-protein	gnl\|CDD\|226318	COG3795, COG3795, Uncharacterized protein conserved in bacteria [Function unknown].	2.13476e-09
NZ_CP045737.1\|WP_153655006.1\|1527322_1528513_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|227277	COG4941, COG4941, Predicted RNA polymerase sigma factor containing a TPR repeat domain [Transcription].	6.41574e-124
NZ_CP045737.1\|WP_153652502.1\|1525321_1526782_+\|YdiU-family-protein	gnl\|CDD\|234583	PRK00029, PRK00029, YdiU family protein.	0
NZ_CP045737.1\|WP_153652499.1\|1522286_1522610_+\|hypothetical-protein	gnl\|CDD\|377177	pfam03961, FapA, Flagellar Assembly Protein A. Members of this family include FapA (flagellar assembly protein A), found in Vibrio vulnificus. The synthesis of flagella allows bacteria to respond to chemotaxis by facilitating motility. Studies examining the role of FapA show that the loss or delocalization of FapA results in a complete failure of the flagellar biosynthesis and motility in response to glucose mediated chemotaxis. The polar localization of FapA is required for flagellar synthesis, and dephosphorylated EIIAGlc (Glucose-permease IIA component) inhibited the polar localization of FapA through direct interaction.	0.000566839
NZ_CP045737.1\|WP_153652504.1\|1528528_1529356_-\|methyltransferase-domain-containing-protein	gnl\|CDD\|273884	TIGR01934, methylase_mitochondrial, ubiquinone/menaquinone biosynthesis methyltransferases. This model represents a family of methyltransferases involved in the biosynthesis of menaquinone and ubiqinone. Some members such as the UbiE enzyme from E. coli are believed to act in both pathways, while others may act in only the menaquinone pathway. These methyltransferases are members of the UbiE/CoQ family of methyltransferases (pfam01209) which also contains ubiquinone methyltransferases and other methyltransferases. Members of this clade include a wide distribution of bacteria and eukaryotes, but no archaea. An outgroup for this clade is provided by the phosphatidylethanolamine methyltransferase (EC 2.1.1.17) from Rhodobacter sphaeroides. Note that a number of non-orthologous genes which are members of pfam03737 have been erroneously annotated as MenG methyltransferases. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone].	3.91556e-24
NZ_CP045737.1\|WP_153652498.1\|1520799_1521984_-\|DUF222-domain-containing-protein	gnl\|CDD\|367155	pfam02720, DUF222, Domain of unknown function (DUF222). This family is often found associated to the N-terminus of the HNH endonuclease domain pfam01844. The function of this domain is uncertain. This family has been called the 13E12 repeat family.	2.89012e-15
NZ_CP045737.1\|WP_153652494.1\|1515691_1516387_-\|ANTAR-domain-containing-protein	gnl\|CDD\|379056	pfam13185, GAF_2, GAF domain.	1.07997e-11
NZ_CP045737.1\|WP_153652506.1\|1530212_1531082_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|375319	pfam17765, MLTR_LBD, MmyB-like transcription regulator ligand binding domain. This domain is found in a family of actinobacterial transcription factors. The structure shows it has a PAS domain like fold and it is bound to Myristic acid.	4.73859e-45

>NZ_CP045737.1|WP_153652501.1|1523909_1525142_+|alpha/beta-hydrolase-fold-domain-containing-protein
MTTSTKYRKLTIGLTAALLLAGGVGAASAGVTEKAPHHGPSASSSKASGWEGVTRKQVRIDLGKGWVTKAELTYPTHAKKRLPLVVMLHGSGHNDMNQTLPGGKGATFLPLAQGVSREGFATLRFNKRGVTGIGPVESKEQNQLNPENPYAQIQKDAASVIRFGAASSKVDASKIFLLGHSEGTNVAANLASDPKKYGIPKPAGVIAMGVVGQDIKELLTLQLYGRLLLQMHDEFDVDADGQLTRTEAVDGLVGQPKDLADQIRPVLLDGDRIQASTDTNKDGKIAIDGEAGAVLRKATGIDNYPDVPGLEDLQEYVADIARFPTVTEALPKFSGPTLLLNGENDLQTPARVALTADAAIGAAGNNKDHEVIIYPGMAHTMNLTRKFVPEFGDPDRQVVKDVRTWLRSHR
>NZ_CP045737.1|WP_153652500.1|1522977_1523628_-|hypothetical-protein
MATFRPSRASQQQENTRLRYIAVLPSLLLIGGVTVGVLSADDRRAALLTYGGLLAVAGLIAAPIIVVLSARNRMLFANSSLTVTPEAVTHVDRRGRPTTFDRSDPTLTSLLTWVEPTALPYGGVFPPKTQLLFIADSTRQVRVAGSDWETDDLRSVTEATNGHAAEGVSTARQVNEAIPGAMSFRELRPLTFALAVGFGSVAFLLMVIVLIAFLLS
>NZ_CP045737.1|WP_153652499.1|1522286_1522610_+|hypothetical-protein
MDVITDEHEGDLIVDDGSDVDVQGTVAGSCEVRGGKLEVHGTVTGDVTVLAGSVTVAGTIAGDLVVSDGTVDVHGTIVGRLIDDGDNQITVHPGAHINGTEAPTVGA
>NZ_CP045737.1|WP_153652498.1|1520799_1521984_-|DUF222-domain-containing-protein
MAITTAPTTESLSDAVRRQARAEAHTVQTMLDYRDAEMARTAQIESSLRRKIERSAIALTIGEATGMSEVQIHLRLSIADRVREKTPLVWEAFVDGLIDFSRVRDISATIEKLHRQESIDRLDDRVIGYATSHTGAELQQWLRRFVQRVESDLATERADAERDQRHVSVTHGDDSMSWLNAYLPSHQAAAIEARLRKEARKSADPDDDRTVPQREADLLVAWCTSSDSVTSAVDANIAVTVGADVLAGATPGFAESTDGAWAVPASWLADVIATGSTFWHRIVVDPVTDDVLAHEYVGRFAPDTLALALQFLHGVCQAPGCMVPSERCDLDHRIPHPAGPTNGDNMGPLCRRHHNLKGHGLLHWSTSPPQPPPEPLVIELYPPRTDFVMEYVAA
>NZ_CP045737.1|WP_153652497.1|1519940_1520720_+|methyltransferase-domain-containing-protein
MSEAEPMVDEFDTVAWWTASAVEELGEDHALPAACRGSGSPAGLDWLATSMGLEPGMRLLDSGAGVGGPAEYVARGYGVRPVLAEPMEGACRAAVRLFDHPTTVADGLRLPFADETFDAAWSLGVLCTIEDKRTYLEELRRSVVPGGAVGLLVYTRGVESLPDQPEGNSFPSRSELLDHLAATGLTVVAETPLADVPATPDDWDQAATEVEQVVERDHRDDERWQRAESQQETIVGLIRDELVVGLLLTCRRSDTATPR
>NZ_CP045737.1|WP_153652496.1|1518930_1519944_+|methylenetetrahydrofolate-reductase
MSSATSCPKAMTFGPCGGVRDDASCEIDPRPCPFAGPAADTVRWERELLPSTTPGSALLEAAEHRPVVLTDLTIPAYDPDGLAEVTRTLADSCDAVLVGEHQNRPDFPPTLMAALIAQAGGVPWVTLACRDRNRVVLEQELAGLAVAGVDGVLCVTGDGRAQGVRPDVTQVFDLDGTQLAALAARAGHAVAVPEAPSAVPQRLRPARLVQKQHAGAHLAVLNHVGTAEEVATFVAASRDLGLTIPVIAAVALYTDERSARVLQNFPGLHLDPDQVAQVLGAADVRSAGIETALDEARALLAIDGVAGVNLSGLASGDGALAGAQVKAETGHLIREGA
>NZ_CP045737.1|WP_153655005.1|1517326_1518805_-|glutamine-synthetase
MVNYAFEPHPIVRLLEKPAAEFTCNDLVHAAEQLELRQVNLRYVGGDGRLKTIAFPIDSQDHLTEVLMQGERVDGSSIFPGVGSEASDVYIVPRHRTAFVNPFGERPSLDVLCSFYDEDGKPLSYAREQVVRRASEVLTEDTGMVLEAFGELEYYLVDEPERVFPVEEEHGYQESSPFSKGEWVREEVLGHLASMGIKLKYAHGEVGNILEEDRQLVQHEIEFWPVPIEQAADALVIAKWVVREVAYQHGLEVTFAPSVSGEGAGSGLHVHSRLVRDGASAITDDGGVNDTGRQLIAGYLSMAKALTAFGNTVPTSYLRFTEGGESPEGICWGETDRTGLVRVPLAWGGGVLPGMVAHANPGSSEPIPEQDIHPQTVELRLGDGSADVHLLLAGMAVAARRGLRDPKSLKLAARLSTEDHSKFEQLPESCAESADALKRDRAALEADGVFPPDLVDAVIEGLRAHDDAKLLKKAARNDETREELVRRYWHVG
>NZ_CP045737.1|WP_153652495.1|1516420_1517308_-|class-A-beta-lactamase
MQGSTWLAAATVLVAAACGPSSAEAPPARASATPDVRDGFAALETSYDTRLGVFAVDTGTGRRVTWRGTERFPFASTIKAPLAAVVLDRTSRRGLARTIHYDASDLLPGSPVTEKHLADGLPLRDLIDAALRFSDNTAANLLFEQIGGPAQLDRELDRIGDRVTNPERTEPDLNSAVPGDVRDTTTPQALATTVGEYVVGKALPRHDRDLLRTTMVDNTTGDALIRAGVPKEWVVADRTGGASHGVRTAVAVAFPPGRSPVLIAVMSRRDQVGDEYDDAVIAEATRIAVGALGLA
>NZ_CP045737.1|WP_153652494.1|1515691_1516387_-|ANTAR-domain-containing-protein
MHHDYSGDQYARMARALAGELGVTATHESATATALSIVDGCDHAGISLVMRNRKIKSVAPTDDVVTRADDLQYETGEGPCLQAIHDQETVYSSDLRSDDRWPSWAPAASSSLGIRTALSLQLFIGPDAMGCLNLYSDQPHAFGPDERVSAHALAAHIAVAMTAATDQENLSSALINRTLIGQAEGMMMQALQITAEQAFAAMVRVSQARNVKVHRVASEIVKNGLKAGLFD
>NZ_CP045737.1|WP_153652493.1|1514206_1515550_-|NADP-specific-glutamate-dehydrogenase
MTDSTLQAVFDQVIARNPGEAEFHQAVREVLDSLGPVVAKHPSYTQAAVIERLCEPERQIIFRVPWVDDAGNVRINRGFRVEFNSALGPYKGGLRFHPTVNVGIVKFLGFEQIFKNALTGLPIGGGKGGSDFDPKGCSEGEVMRFCQSFMTELYRHIGEYTDVPAGDIGVGGREIGYLFGQYKRITNRYESGMLTGKGITWGGSQVRKEATGYGTVFFVEEMLKQQRETFEGKRVVVSGSGNVAIYAMEKVVQLGGTVVAFSDSSGYVVEEDGVDVETLKQVKEVERGRIADYVERRGGRALLGSSGSIWDVPTDIALPCATQNELDEDHAATLVRNGCRIVAEGANMPTTAAATKVLADAGVLFAPGKAANAGGVATSALEMQQNASRDSWSFEHTERRLDEIMRGIHDRCLATADEYGVPGDYVAGANIAGFTHVADAMLALGVI
>NZ_CP045737.1|WP_153652502.1|1525321_1526782_+|YdiU-family-protein
MTTTPVTFPLTHRFATELPELALPWQAEQTPAPQLLALNDRLAAELGLDPEALRAPDGLGLLTGTVVPPGATPVAQGYAGHQFGGYSPRLGDGRALLMGELTDREGRPRDLHLKGSGRTPFSRGGDGLAAVGPMLREYVVSEAMHALGVPTTRALAVVATGRRVRRETLLPGAVLARVASSHLRVGTFQYVASARDLELLRRLADHAIERHHPDAASADNPYRALFEAVVVAQADLVARWMLVGFVHGVKNTDNVTISGETIDYGPCAFLETYDPATVFSSIDVDGRYAYGNQPAVAQWNLARFAETLLPLLAEDQDAAVAMAMESLDTFGSRYAATYAAGLRAKIGLAPTGQDAAAAQLGEELLELLRGGHVDWTTGFRALGAAARGDAEPVRGLVVDLASIDDWLARWRALGPDPDLMDRTNPVYVPRNHLVEEALDAATAGDLDPFERLVEAVRQPFDERPGLERFAAPAPQDFGRYTTYCGT
>NZ_CP045737.1|WP_153652503.1|1526885_1527260_+|hypothetical-protein
MPRFMGLVRMEEGVGTPPQALFEAMDAYIGKQAANGVFLDGGGLYGTEDAVNFVSHKGEVSRVDGPYAEAKEVVGGWAILDYESLEDAVADQQEFAELHAKHWPEVTVISTLRQISTGPEAPGE
>NZ_CP045737.1|WP_153655006.1|1527322_1528513_+|sigma-70-family-RNA-polymerase-sigma-factor
MTRDVQLAEDLAQDALVAALEQWPTDGVPDNPSAWLMTTAKRRGIDHFRRAEVLRRKVTEVGRARGEEQAMPDLDAQVDHIEDDVLRLIFLTCHPALTAESRAALTLRLVGGLTTAEIARGFLTTESAMGQRISRAKKTLATARVELELPTGEERTRRLDDVMAVIYLIFNEGYTATAGQDWMRPELSNEATRLARMLAALAPDEPEVLGLQALLELQGSRTTARLDESGMPVLLEAQDRTRWDHLLIRRGLAALQRAEAFARRGKPVGTYFLQASIAAQHAKAKQPEHTSWRRIAALYDVLAEVAPGPVVELNRAVAHGRAHGPTAGLAVLDALGPDALAGSPLVPSVRGDLLERAGLHERASEAFAEAASRTSNGSERALLHRRAQANAARSPG
>NZ_CP045737.1|WP_153652504.1|1528528_1529356_-|methyltransferase-domain-containing-protein
MAERADATRDAHFLGPVPDLYQRLLVPMIFQGAADSLARSVAGLAPATILETAAGTGALTRAMVRHCPGSVITATDLHQPMLDAAAAIGADGGSVTWQQSDALDLPFGDRTFDVVACQFGVMFFPDRVRAFREAARVLKPGGSFVFNTWDRIERNEVVHVIQSALVAAAPHDPLVFMSRTPHGYFSPAQILGDLEAAGMPGATIHAVDATGRTTASEAAAAFCGGTPLRAAIEAHDSLSLDEARAIAEAALVAHFGAGPIDGPIRSFEVVARPPT
>NZ_CP045737.1|WP_153652505.1|1529388_1530075_-|SDR-family-NAD(P)-dependent-oxidoreductase
MTITLITGANKGIGLETAKQLVALGHTVYLGARDRERGEKAAAEAGGTFVQLDVTDEDSVIAALASIEAAEGRLDVLVNNAGIFGSWTPDGPTALRVFDTNVVGIVRVTEAALPLLRRSERPVVVNVSSSLGSFWAVTDPDRPEFTIPAALYAASKSAVTMLTVQYAKADPDIRFNAVEPGLTDTDLTADQSAGRPAEESARFVVRWATIGADGPTGTLQDESGVLAW
>NZ_CP045737.1|WP_153652506.1|1530212_1531082_+|helix-turn-helix-domain-containing-protein
MTNRPNTLGEFLQARRGLVTPQAAGIPDSGTRRVAGLRREEVAMLAGVSVDYYLRLERGRDRNPSVQVLESIARVLQLDDDHLAYLMTLVGDRPRRSPRRSRTETVPPGMATLVASMPHPAYVEGRYFDVLVSNPVAVALSPRFAVGGNQLRDMFLDPQQQELYPDWRGSTECLVANLRHSVGPDIEDPRFIELVGELSLASPRFRELWARHDIKKQFGAPMRFDHPQVGGMTLNREWLSIGGTEGLHLVVYHPDPGSEAADKIGLLASAALPTKDAMSQRGCAGRARD
>NZ_CP045737.1|WP_153652507.1|1531091_1531640_+|formimidoyltetrahydrofolate-cyclodeaminase
MVSDADVDARTVTEFLADLSARTPTPAGGAVAALCAAQAAALVAMVARYCEDAALVERAEALLLRAQQLVVDDERAFGAVAVAWGAPADDEGRRAAIDAALLAASEPQAQVVETVIEVLVLIDQLRPAARPGLRSDLVAAGEVARAGAAVARMNVESNVRELPDSEGRSQLLRRMGVTKERN
>NZ_CP045737.1|WP_153652508.1|1531640_1533320_+|formate--tetrahydrofolate-ligase
MLSDIEIANAAELRPIAQVAQDELGIDPAHLVPYGHHKAKVDLGFLESLQDRPLGKLVLMTAMSPTPAGEGKTTTTVGLADALSGLGLTTMACLREPSMGPVFGMKGGAAGGGWAQVVPMSDINLHFTGDFAAIAAANNLLAALIDNHIHHGNALGIDVRSVDWKRVVDLNDRALRDVTVGLGGPANGYPREEGFDIVVASELMAIFCLTESWADLKRRIGDIVVAHTRDKRPITARDLEAAGAMAVLLRDALAPNLVQTLEHTPAFVHGGPFANIAHGCSSVVATRAALRLADYVVTEAGFGADLGAEKFVDIKCRKSGLRPDAAVVVATVRALKFHGGVAAADLHVEDLDAVERGMENLARHLRNVREVYGIPCVVALNRFPTDTDAEVARVVELVGELGVQAHPATHFVDGGVGATDLAKGVLDLIETSGPSTFSFTYPDGLPLKEKAETIAHRLYGASSVTWDGKARRRLDRLEADGYGGLPVCVAKTQYSFSTDPASLGAPTGHDLHVREVRLSAGAGFVVLVCGDVMTMPGLPAVPAASRIDLLDDGTIVGLS
>NZ_CP045737.1|WP_153652509.1|1533356_1533752_+|RNA-methyltransferase
MAYDEALAARIRSAVEDAAAPEGCREIAMFGGLCWTVNTHMAVGAGDDDLMVHVGTDGVEQALALGARRATMGARTMGGVVLVAGADLPDAAALDAWVVPAVERARARPAKRPAGPSGRATPPASGRSRRP
>NZ_CP045737.1|WP_153652510.1|1533675_1534605_-|hypothetical-protein
MAASGHDERELTATFFALRVGLVVAAVFVLLAPVLLLVVQGELPPTISDSWWTDARTIFVVGVSAASCLLVVVRGDSLTEQTLLNLAGALGFVVASVACVPRDENGAPLAVYDPDVVQLNRFALIGLLTIGLLAWVVGALLPAAMRGPDWRVDGWPRRILTGALPALLLVGVVAFVVDGDALARHAHSPAAVAMFALLGLVAMLRTTRGAHVLRRIGDIPTERSLTSMRLSPSPGSAVPLTRFDALYTVVATSMLLIEIIAVVLFLTVEEPGWLLFVETALLLLFMVFWIAQTREAWLALRDPPAAWRV

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP045737_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045737_9

1580285-1580372

Orphan

Consensus_repeat	Method
ACCGACGATGAGGGTTTCCGGCAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045737_9

>merge|NZ_CP045737|9|1580285-1580372|CRISPRCasFinder
ACCGACGATGAGGGTTTCCGGCAGTCCCAGCAGCCCCTAGCCCTCATCCTTCGTCCGCACCGGCACGGACGATGAGGGTTTCCGGCAG

>NZ_CP045737|9|9|1580285-1580372|CRISPRCasFinder
ACCGACGATGAGGGTTTCCGGCAG	TCCCAGCAGCCCCTAGCCCTCATCCTTCGTCCGCACCGGC
ACGGACGATGAGGGTTTCCGGCAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045737.1\|WP_153652546.1\|1574472_1575918_-\|amino-acid-permease	unknown	unknown	gnl\|CDD\|129987
NZ_CP045737.1\|WP_153652545.1\|1573361_1574411_+\|TerC/Alx-family-metal-homeostasis-membrane-protein	unknown	unknown	gnl\|CDD\|274743
NZ_CP045737.1\|WP_153652554.1\|1584095_1585049_+\|DUF808-family-protein	unknown	unknown	gnl\|CDD\|377542
NZ_CP045737.1\|WP_153652561.1\|1592183_1592987_+\|triose-phosphate-isomerase	unknown	unknown	gnl\|CDD\|234589
NZ_CP045737.1\|WP_153652550.1\|1579401_1579578_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045737.1\|WP_153652543.1\|1571572_1572355_+\|aldose-1-epimerase	unknown	unknown	gnl\|CDD\|224928
NZ_CP045737.1\|WP_153655010.1\|1578995_1579409_+\|SRPBCC-family-protein	unknown	unknown	unknown
NZ_CP045737.1\|WP_153652553.1\|1581217_1584076_+\|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl\|CDD\|234734
NZ_CP045737.1\|WP_153652547.1\|1576015_1577296_+\|cytochrome-P450	unknown	unknown	gnl\|CDD\|225035
NZ_CP045737.1\|WP_153652549.1\|1578333_1578615_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045737.1\|WP_153652557.1\|1587875_1588853_+\|uridine-diphosphate-N-acetylglucosamine-binding-protein-YvcK	unknown	unknown	gnl\|CDD\|211689
NZ_CP045737.1\|WP_153652560.1\|1590979_1592182_+\|phosphoglycerate-kinase	unknown	unknown	gnl\|CDD\|234613
NZ_CP045737.1\|WP_153652558.1\|1588892_1589876_+\|DNA-binding-protein-WhiA	unknown	unknown	gnl\|CDD\|273194
NZ_CP045737.1\|WP_153652559.1\|1589973_1590978_+\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|223135
NZ_CP045737.1\|WP_153652555.1\|1585078_1587022_+\|excinuclease-ABC-subunit-UvrC	unknown	unknown	gnl\|CDD\|234792
NZ_CP045737.1\|WP_153652556.1\|1587018_1587879_+\|RNase-adapter-RapZ	unknown	unknown	gnl\|CDD\|235450
NZ_CP045737.1\|WP_153652551.1\|1579656_1579923_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045737.1\|WP_153652548.1\|1577317_1578301_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045737.1\|WP_153652552.1\|1580424_1581078_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293792
NZ_CP045737.1\|WP_153652544.1\|1572361_1573132_+\|aldose-1-epimerase	unknown	unknown	gnl\|CDD\|224928

Protein	Function_ID	Function_description	E-value
NZ_CP045737.1\|WP_153652546.1\|1574472_1575918_-\|amino-acid-permease	gnl\|CDD\|129987	TIGR00909, putative_amino_acid_transporter, amino acid transporter. [Transport and binding proteins, Amino acids, peptides and amines].	9.14286e-46
NZ_CP045737.1\|WP_153652545.1\|1573361_1574411_+\|TerC/Alx-family-metal-homeostasis-membrane-protein	gnl\|CDD\|274743	TIGR03718, R_switched_Alx, integral membrane protein, TerC family. Rfam model RF00080 describes a structured RNA element called the yybP-ykoY leader, or SraF, which may precede one or several genes in a genome. Members of this highly hydrophobic protein family often are preceded by a yybP-ykoY leader, which may serve as a riboswitch. From the larger group of TerC homologs (pfam03741), this subfamily contains TerC itself from Alcaligenes sp. plasmid IncHI2 pMER610 and from Proteus mirabilis. It also contains the alkaline-inducible E. coli protein Alx, which unlike the two TerC examples is preceded by a yybP-ykoY leader.	1.55471e-132
NZ_CP045737.1\|WP_153652561.1\|1592183_1592987_+\|triose-phosphate-isomerase	gnl\|CDD\|234589	PRK00042, tpiA, triosephosphate isomerase; Provisional.	7.61123e-138
NZ_CP045737.1\|WP_153652543.1\|1571572_1572355_+\|aldose-1-epimerase	gnl\|CDD\|224928	COG2017, GalM, Galactose mutarotase and related enzymes [Carbohydrate transport and metabolism].	2.12599e-36
NZ_CP045737.1\|WP_153652558.1\|1588892_1589876_+\|DNA-binding-protein-WhiA	gnl\|CDD\|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	2.04344e-126
NZ_CP045737.1\|WP_153652553.1\|1581217_1584076_+\|excinuclease-ABC-subunit-UvrA	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
NZ_CP045737.1\|WP_153652547.1\|1576015_1577296_+\|cytochrome-P450	gnl\|CDD\|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	2.19148e-71
NZ_CP045737.1\|WP_153652560.1\|1590979_1592182_+\|phosphoglycerate-kinase	gnl\|CDD\|234613	PRK00073, pgk, phosphoglycerate kinase; Provisional.	0
NZ_CP045737.1\|WP_153652559.1\|1589973_1590978_+\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	gnl\|CDD\|223135	COG0057, GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism].	7.73592e-179
NZ_CP045737.1\|WP_153652555.1\|1585078_1587022_+\|excinuclease-ABC-subunit-UvrC	gnl\|CDD\|234792	PRK00558, uvrC, excinuclease ABC subunit UvrC.	0
NZ_CP045737.1\|WP_153652556.1\|1587018_1587879_+\|RNase-adapter-RapZ	gnl\|CDD\|235450	PRK05416, PRK05416, RNase adapter RapZ.	4.76039e-147
NZ_CP045737.1\|WP_153652554.1\|1584095_1585049_+\|DUF808-family-protein	gnl\|CDD\|377542	pfam05661, DUF808, Protein of unknown function (DUF808). This family consists of several bacterial proteins of unknown function.	5.82299e-156
NZ_CP045737.1\|WP_153652557.1\|1587875_1588853_+\|uridine-diphosphate-N-acetylglucosamine-binding-protein-YvcK	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	2.05479e-90
NZ_CP045737.1\|WP_153652552.1\|1580424_1581078_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293792	cd06262, metallo-hydrolase-like_MBL-fold, mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases which can catalyze the hydrolysis of a wide range of beta-lactam antibiotics, hydroxyacylglutathione hydrolases (also called glyoxalase II) which hydrolyze S-d-lactoylglutathione to d-lactate in the second step of the glycoxlase system, AHL lactonases which catalyze the hydrolysis and opening of the homoserine lactone rings of acyl homoserine lactones (AHLs), persulfide dioxygenase which catalyze the oxidation of glutathione persulfide to glutathione and persulfite in the mitochondria, flavodiiron proteins which catalyze the reduction of oxygen and/or nitric oxide to water or nitrous oxide respectively, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J which has both 5'-3' exoribonucleolytic and endonucleolytic activity and ribonuclease Z which catalyzes the endonucleolytic removal of the 3' extension of the majority of tRNA precursors, cyclic nucleotide phosphodiesterases which decompose cyclic adenosine and guanosine 3', 5'-monophosphate (cAMP and cGMP) respectively, insecticide hydrolases, and proteins required for natural transformation competence. The diversity of biological roles is reflected in variations in the active site metallo-chemistry, for example classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, human persulfide dioxygenase ETHE1 is a mono-iron binding member of the superfamily; Arabidopsis thaliana hydroxyacylglutathione hydrolases incorporates iron, manganese, and zinc in its dinuclear metal binding site, and flavodiiron proteins contains a diiron site.	3.60497e-39
NZ_CP045737.1\|WP_153652544.1\|1572361_1573132_+\|aldose-1-epimerase	gnl\|CDD\|224928	COG2017, GalM, Galactose mutarotase and related enzymes [Carbohydrate transport and metabolism].	3.54558e-34

>NZ_CP045737.1|WP_153652551.1|1579656_1579923_-|hypothetical-protein
MRSPRTLFIAAGLLLAVGIVLVLTSDSGQVSEYGWFAYAPESDSISMGGSFVVLTTREVLGWSAGWLGTLLAAAAMGYRFAARRRASD
>NZ_CP045737.1|WP_153652550.1|1579401_1579578_-|hypothetical-protein
MEESIGRLVWAVLTGVATVLLWEALRRTRMNDYSRALPPVVAVLISLVALTSLRMALS
>NZ_CP045737.1|WP_153655010.1|1578995_1579409_+|SRPBCC-family-protein
MTYESRHIARTIDRDADTVYLYASDPRHLPDWAAGLSTTISLVDGQWVAESDLGRITVELADDNPFGVLDHTVVLPDGTRVHNPLRVVPNGEGCDVVFSLFRLPGVDEAAFEADAAAVAADLETLKSVVEALPEEVS
>NZ_CP045737.1|WP_153652549.1|1578333_1578615_+|hypothetical-protein
MNPNGTRNGRPLAAGDPYAVPVPQPPPVYHVWVNLSNLTTQVAQEYPGLVLGWRRSSDGYEAQVVYIIPGKTQRHSDASQIAWLPASKLKPRE
>NZ_CP045737.1|WP_153652548.1|1577317_1578301_+|hypothetical-protein
MIAPAETGTRIEAWFDDHGLPYFTGDHADRVEGWLSSKRIVAAIVLIIGVSITIGVAVGAVWADQGSVGTFVGVLVFLALLGLFAGRLLRMGTMLRWAARRTFGSLGLMFPLLTRALPLLLLAVTFLFINAEVWQVAALMSRHVLWLAVLFFAVIAVVFLLARLPEEVRRVEREVVGDRVAERCVGTPAEEASRSVTALPADLPRFARVNLVLVLLFNQAIQVLLLTLGLFAFFMVFGSLTIPDGTVEAWTGETVTRLPSALGRHVPVTNELFQVAVFLAAFAGLYFTVYAVTDETYRSQFFAGLSAELEQAVAVNAVYVSLARDPH
>NZ_CP045737.1|WP_153652547.1|1576015_1577296_+|cytochrome-P450
MLEVKGRVRRWVGRMLVKRIQKNGIDLSALSFIPELTKVPLQRDVMDPLPQIAEWRASEPMRKLELPFTFTAYLVTGYDEARTVLTDRDSYSNDIRHLFHGDGPATADDIGGLGFTDPPLHTRLRKIVTPEFTMRRLARLEPLITEFVDAQLDQLEAEGPGADLCKAVAFPIPFQTICALLGLDYADSQAFAKLGSDRFDATNGGAAAFGAVSDQRKFLFEAVARQRKQPGPGLLGQIIRDEGETISDFDLAGLADGVFTGGFETTAGMIALGTIVLLRDPEHAELMRRGDPADVDRIVEELLRYLSVVQVAFPRFAKRDMELFGTQVKAGDVILTSLAGANRDPDSAGEDPDGFDPFRTPSSGHLAFGHGIHRCIGAELARMELRIALPKLFQRFPDLALAKPQHELSFRQLSFVYGVDELKVNF
>NZ_CP045737.1|WP_153652546.1|1574472_1575918_-|amino-acid-permease
MSTDTAESGQPHELKRVMGPRLLLLFIVGDILGAGVYAVTGEMAAGVGGIVWLPFLLAFIVATVTALSYLELVTKYPQAAGAALYAHKAFGVHFITFIVAFAVVCSGITSASTASATLAGFLTDGLQINGWIDGDVSEGTITAVAMGFMVLLAVINLRGVGESVKFNVVLTLVEISALLIVIGVGFYVIAQGDGDLSRITVFEDANDKGMFLAVTTATSIAFFSMVGFEDAVNMVEEVENPQKIFPRTMLTGLGIAVILYMLVAISVVSVLTSDQIKEINDNGDRALLSVVSIGAPDFPIDKVFPFLAVFAVANTALINMLMASRLIYGMARQDVLPRQLGAVLPGRRTPWAGILFTTLLALGLILYVRQDPDSDIVVNLATVTSLLLLCVFAVVNIACMVLRRKKHDHVKTVFRSPGPLPVVGALLCLFLAGPWVERDSIVYEIAGGLMVIGIVLWVITFAINKATGQGDSNFQDVDSLE
>NZ_CP045737.1|WP_153652545.1|1573361_1574411_+|TerC/Alx-family-metal-homeostasis-membrane-protein
MSVSQTEWIVTISVTIAVLLFDIIIVARKPHEPTLKECAAYLTGYVGLAIAFGIWVMVHHDVKPGPGEKGGDFGLQFFAGWLTEYSLSIDNLFIFLIIMASFKVPRKLQQEALLVGIIIALVFRGIFIAIGAVAIENFSWIFYIFGAFLLWTAYTLVKDKDHDDDGENAVVRMARRFFNVKDEWHGLKLFIKENKKTYITPMFLVILSLGTTDLLFALDSIPAIYGLTQEPYLVFTANVFALMGLRQLYFLLGDLLTKLIYLSQGLSVLLAFIGVKLVLHALHENELPFINGGEHVKVPEIPTLLSLGVIVGVLAVTAIVSLTVSSRRERAGLAADGQPKSSDPDDTQR
>NZ_CP045737.1|WP_153652544.1|1572361_1573132_+|aldose-1-epimerase
MVPVNPVIENARIRAEIDPSLGARLHQLTIDGLELLGPDGCFPMVPWAGRIRDGLLHVDGQTYELPQAPDGHAIHGLGRKIEWENAGDGVFRRRLGAPWPSEGTAELRYTLLDDGLRIELSWDDGTDLPCSIGLHPWFRRRLATGEEISMSLDIDEMVERGPDGLPTGHLVAPKEQPWDDCFRLGLPPVLTWPGALELTLTASTPWWVVLTDREHFVCVEPQTAPPDAFDHPTLQPEGGWPRSLWFELRARSLRTS
>NZ_CP045737.1|WP_153652543.1|1571572_1572355_+|aldose-1-epimerase
MTDVLENDRVRATIDPARGARLTSLVIDGHELLARAEDPSVDPAIADGCFAMVPWAGRVREGRLRTADGVHQLPVSDDGNALHGLGHVEVWDVVGEGRYRLGLGEPWPTTGTASLTYRLLDAGLRIELSWDDGTASPCSIGLHPWFPRRLPTGQEVVLSFDPETMVERGDDGLPTGRLVEPSPGPWDDCFRVAGSPVLSWPGAVRLRLSSSSPWWVVYSQPESTICVEPQTAPPDAFDHASLQPTGGWPHHLWFELDAAE
>NZ_CP045737.1|WP_153652552.1|1580424_1581078_-|MBL-fold-metallo-hydrolase
MTYTGEVEVGGPADVQVAGDLMITKIAVGEMNNNAYLLRCVLTGEQVLIDAAAEYERLLELIGPDGLARVVTTHRHGDHWQALATVVERTGAETVAGERDADELPVPVDVRVQTGARVRVGSCELEVIEVAGHTPGSIVLAYDDPDGIVHLFTGDSLFPGGVGKTWSPDDFTTLIDEVETKIFGAYPDDTHVYPGHGHDTTLGAERPHLAEWRARGW
>NZ_CP045737.1|WP_153652553.1|1581217_1584076_+|excinuclease-ABC-subunit-UvrA
MTDRLVIRGAREHNLKDVSLDLPRDSLIVFTGLSGSGKSSLAFDTIFAEGQRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKSTSRNPRSTVGTITEVYDYLRLLYARAGRAHCPQCGEPIARQTPQQIVDRILAGEEGTRFQVLAPVIRGRKGEYLELFRQLQTQGFSRTIVDGEVHMLADEPPKLAKQKKHTIDVVVDRLQVKKSQQQRLTESIETALGLADGLVIIDYVDLDPKDENRTRRFSEKLACPNDHPLEVDELEPRSFSFNAPFGACPECHGLGTRMEVDPELVVPDDAKSLNEGAVVPWASAHVADYYSRLIGALADELGFSADTPWGDLSDEVKDAILRGHSTKVHVRYKNRYGRVRSYYTEFEGAITYIERRHAETESDTSKERLEGFMREVPCRVCNGTRLRPVILAVTLNSTEYGPKNIAEVCAMSISEAADYLKTLEMSDRERQIGEQVLKEINERLRFLLDVGLDYLALDRAAGTLSGGEAQRIRLATQIGAGLVGVLYVLDEPSIGLHQRDNQRLIETLVRLRDLGNTLIVVEHDEDTIRAADWAVDIGPGAGEHGGQVIVSGPVKELYESKDSLTGQYLSGRKSIPLPEKRRKRVKGRELRVRGAKENNLRNIDVTFPLGMLVAVTGVSGSGKSTLVNDILYTQLARTVYGARTIPGRHRAIDGLDQIDKVIHVDQSPIGRTPRSNPATYTGVFDHVRKLFAQTPEAKMRGYQQGRFSFNVKGGRCEACSGDGTIKIEMNFLPDVYVPCEVCHGARYNRETLEVHYKGKSIADVLDMPIEEAVDFFEAHNVIARHLRTLVEVGLGYVRLGQPATTLSGGESQRVKLSAELQKRSTGRTVYVLDEPTTGLHFEDIRKLLGVLQRIVDTGNSVIVIEHNLDVIKTSDWVLDMGPEGGSGGGLLVAEGTPEDIAKSPESHTGRFLKPLLG
>NZ_CP045737.1|WP_153652554.1|1584095_1585049_+|DUF808-family-protein
MAGGIFALLDDVAAIARIAAASIDDVGAAAGRASVKAAGVVVDDTAVTPQYVQGVAAKRELPIIKKIAIGSLRNKILFILPAALLLSQFLPWLLTPLLMVGGTYLCFEGAEKIWERISGHHEAEVEEASTELDPEHEATMVSGAIRTDFILSGEIMVIALNEVTDEPFVARAAILLVVAIAITLLVYGVVALIVKMDDVGVHLTQRSSALLQRVGHGLVKFMPVLLAIISTVGIAAMVWVGGHIILVGVDDLGFHPPYDFVHHLEEDVHHAMGAFGAVAGWLTNTVASALIGLVWGAIVVAIWHVIPRPGKHATDHA
>NZ_CP045737.1|WP_153652555.1|1585078_1587022_+|excinuclease-ABC-subunit-UvrC
MADPASYRPAPGEIPTEPGVYRFRDAERRVIYVGKAKSLRPRLSSYFQDITNLHPRTQQMVMTASSVEWTVVSTEVEALALEYSWIKEFDPRFNVKYRDDKSYPWLAVTVSEEFPRVTVMRGAQRKGVRYFGPYGHAWAIRDTVDTLLRVFPMRSCSAGVFRRAKAIGRPCLLGDIGKCAAPCVGRVSPEEHREIVNDFLAFMGGQTAGFTKRIETKMLEASAREEYELAAKLRDDLGALRRVLEKQTVVLGDGTDADVLGFVEDPLEVAVQIFSVRGGRIRGQRGWVAEKSDEAEFPELVQRALMTLYQDAAPSAIPREVLVPEMPLDASTITELLSERREGPVRIRVPQRGDKRALMETVTQNAKQSLMRHKMKRTSDLTARSLALEEIQEALDLETAPLRIECYDISNLGATETVASMVVFEDGLPRKSEYRRFTIRNEGQSDVAAMHEVITRRFTQLLRARDENDDDGPGIDPETGKPRRFAYKPSLVVVDGGPPQVAAAHQAMQELGVTDVALVGLAKRLEEVWLPEDEDPVILPRTSEGLYLLQRLRDEAHRFAITHHRGRRSKSMIESVLDPVAGLGPTRRKALLKTFGSVKKLRSATAEEIATVPGIGPATAQSIVEALATGESAPTINTATGEILEDS
>NZ_CP045737.1|WP_153652556.1|1587018_1587879_+|RNase-adapter-RapZ
MTTLSQLVLVTGMTGAGRGSAAKVLEKLDYYVIDNLPPSLLHGAVDTVQKSGIARLAVVVDARSRQFFGELMEALESLREVGVDTRILYLEASDEVLVRRQEAARRPHPLSLEGRLLDGFERERELLRQLRGRADIVVDTTNLNVHQLGQRVHAAFEDADSGGLRASVVSFGFKYGIPIDADMVADLRFLPNPYWIDELRPLSGLDTPVSDYVLTQPRAEEFLEQYERLVALLTDGYLREDKHFLTIAIGCTGGRHRSVAMSEAFAERLRSHGVRTLVVHRDLGRE
>NZ_CP045737.1|WP_153652557.1|1587875_1588853_+|uridine-diphosphate-N-acetylglucosamine-binding-protein-YvcK
MIPRTPRPARPERFDGDLKVVSLGGGHGLAASLSALRRLTTELTGVVTVADNGGSSGRLREELGGLPPGDLRMALAALCGDDDWGRTWASVLQHRFSSGGPLNGHAVGNLLIAALWDQHDHVAGLDLVGDLLGAQGRVLPMASVPLDIEADVRLTSDPDRLTIVRGQVQVASVDGQVVTVRLDPSDPPACPQAVEAVEVADWVVVGPGSWFTSVMPTLLVPELRDALISTPARRVLVLNLTEQDGETEGLSPTDHLEVLAAHAPELRLDAVIADTSLVDMRGTLEAAARGLGATLFVSDLAVTPGSDQHDPASLAAAFGHVMRQA
>NZ_CP045737.1|WP_153652558.1|1588892_1589876_+|DNA-binding-protein-WhiA
MAMTAQVKAELANTSITKSCCRKAEVSSILRFSGGLHIVSGRIVVEAEVDTGAAARRLRKDIAEIYGHDSEILVVQNAGIRKDTHYVVRVSKDGEALARQTGLIDGSGRPIRGLPPQVVSGSSCDAVAAWRGSFLAHGSLTEPGRSSALEVSCPSPEAALALVGAARRVGISAKAREVRGIDRVVIRDGEAIGALLTRLGAHESLLAWEERRMRREVRATANRLANFDDANLRRSARAAVAAGARAQRALEILGDEVPDHLKMAGTLRVEHRQASLEELGQLHEPALTKDAIAGRIRRLLAMADKRAEDLGIPDTESSLGDDNLGID
>NZ_CP045737.1|WP_153652559.1|1589973_1590978_+|type-I-glyceraldehyde-3-phosphate-dehydrogenase
MTVRVGINGFGRIGRNFFRAARAAGADIEIVAVNDLTDNKTLAHLLKYDSILGRLDADVTYDETSIYVGEQKIVAFEERDPAKLDWASVGVDIVIESTGFFTDATKAKAHIDGGAKKVIISAPAKNEDVTIVMGVNHELYDPAAHTVISNASCTTNCLAPMAKALNDALGIEKGLMTTIHAYTQDQNLQDAPHSDLRRARAANLSIIPTSTGAAKAVSLVLPELKGKLDGYALRVPVPTGSATDLTFTASRETTVEEVNQIVKDAAEGAMKGFLVYTEDPIVSADIVTDPASCIFDSGLTKVIGDQVKVVGWYDNEWGYSNRLADLVVHVGASL
>NZ_CP045737.1|WP_153652560.1|1590979_1592182_+|phosphoglycerate-kinase
MRTVSDLGDLRGKRVLVRSDLNVPLDGTTITDDGRVRASVPTIKSLADAGARVLVTAHLGRPKGAPDAAYSLAPVAARLAELLGAPVEFAGDTVGPEAQRVSAGLRDGQVAVLENVRFNAGETSKDDAERGAFADQLAALADVFVSDGFGVVHRKQASVYDVATRLPAAVGGLVEAEVTVLKRLTESPERPYTVVLGGSKVSDKLGVIDNLLDKADHLLIGGGMVFTFLKAQGHEVGTSLLEEDQLEVARGYIEQAKAQGVTLLLPTDIVVAPEFKDAGATVVAADAIPADQLGLDIGPDSAAAFAEVIRGSRTVFWNGPMGVFEMASFAAGTKAVAQALTEVDGLSVVGGGDSAAAVRQLGFADDQFGHISTGGGASLEYLEGKTLPGLAILDQQSEGN
>NZ_CP045737.1|WP_153652561.1|1592183_1592987_+|triose-phosphate-isomerase
MASARTPLMAGNWKSNLDHQEALVLVQKLAWTLQDKKHDYDKAEVVVVPPFTDLRSVQTLVDGDHLSIRYGAQDVSEHDGGAYTGEVTAAMLAKLGCSYVVVGHSERREYHGETDQQVNVKATKALGAGMSPIVCVGEGLEVRQSGQHVAYTLDQVDGSLAGLTAEQMADVVIAYEPVWAIGTGEVATPEDAQEVCAAIRGRVEETWSSEVAAATRILYGGSVKAANIAAIMAKSDVDGALVGGASLQAEEFAAIARFYAMPDLSGA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP045737_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045737_10

2590727-2590823

Orphan

Consensus_repeat	Method
GAGTCACGTACGGACGCCCGCGAGTCACGCACGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045737_10

>merge|NZ_CP045737|10|2590727-2590823|CRISPRCasFinder
GAGTCACGTACGGACGCCCGCGAGTCACGCACGGCGGCCGACGAGTCACGCACGGCGGCCGACGAGTCACGCACGGCGGCTGAGGAGTCACGTACGG

>NZ_CP045737|10|10|2590727-2590823|CRISPRCasFinder
GAGTCACGTACGGACGCCCGCGAGTCACGCACGG	CGGCCGACGAGTCACGCACGGCGGCCGAC
GAGTCACGCACGGCGGCTGAGGAGTCACGTACGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045737.1\|WP_153653564.1\|2590987_2592748_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP045737.1\|WP_153653561.1\|2586568_2588023_-\|ATPase	unknown	unknown	gnl\|CDD\|226434
NZ_CP045737.1\|WP_153653539.1\|2582368_2582542_+\|DUF1059-domain-containing-protein	unknown	unknown	unknown
NZ_CP045737.1\|WP_153655085.1\|2582666_2583290_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|226425
NZ_CP045737.1\|WP_153653581.1\|2599673_2600480_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378566
NZ_CP045737.1\|WP_153653566.1\|2592744_2594499_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP045737.1\|WP_082530375.1\|2586244_2586496_+\|WhiB-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|376791
NZ_CP045737.1\|WP_153653572.1\|2595552_2595981_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045737.1\|WP_153655086.1\|2588088_2588979_+\|DUF2785-domain-containing-protein	unknown	unknown	gnl\|CDD\|371322
NZ_CP045737.1\|WP_153653574.1\|2595977_2596367_-\|pilus-assembly-protein	unknown	unknown	gnl\|CDD\|377921
NZ_CP045737.1\|WP_153653541.1\|2583373_2584342_-\|zinc-binding-dehydrogenase	unknown	unknown	gnl\|CDD\|176227
NZ_CP045737.1\|WP_153653578.1\|2597453_2598314_-\|type-II-secretion-system-protein-F	unknown	unknown	gnl\|CDD\|227300
NZ_CP045737.1\|WP_153653562.1\|2589024_2590716_+\|acetolactate-synthase	unknown	unknown	gnl\|CDD\|235629
NZ_CP045737.1\|WP_153653559.1\|2585695_2586091_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045737.1\|WP_153653568.1\|2594525_2595062_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372724
NZ_CP045737.1\|WP_153653537.1\|2578333_2582128_+\|multifunctional-oxoglutarate-decarboxylase/oxoglutarate-dehydrogenase-thiamine-pyrophosphate-binding-subunit/dihydrolipoyllysine-residue-succinyltransferase-subunit	unknown	unknown	gnl\|CDD\|237030
NZ_CP045737.1\|WP_153653579.1\|2598301_2599540_-\|CpaF-family-protein	unknown	unknown	gnl\|CDD\|227297
NZ_CP045737.1\|WP_153653570.1\|2595150_2595549_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379164
NZ_CP045737.1\|WP_153653557.1\|2584360_2585563_-\|NAD-dependent-malic-enzyme	unknown	unknown	gnl\|CDD\|223358
NZ_CP045737.1\|WP_153653576.1\|2596542_2597457_-\|pilus-assembly-protein-TadB	unknown	unknown	gnl\|CDD\|366122

Protein	Function_ID	Function_description	E-value
NZ_CP045737.1\|WP_153653564.1\|2590987_2592748_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.89532e-87
NZ_CP045737.1\|WP_153653561.1\|2586568_2588023_-\|ATPase	gnl\|CDD\|226434	COG3920, COG3920, Signal transduction histidine kinase [Signal transduction mechanisms].	8.35431e-46
NZ_CP045737.1\|WP_153655085.1\|2582666_2583290_+\|AAA-family-ATPase	gnl\|CDD\|226425	COG3910, COG3910, Predicted ATPase [General function prediction only].	6.73157e-60
NZ_CP045737.1\|WP_153653581.1\|2599673_2600480_-\|hypothetical-protein	gnl\|CDD\|378566	pfam11139, SfLAP, Sap, sulfolipid-1-addressing protein. SAP is a transmembrane transport protein with six predicted transmembrane helices, with a hydrophilic domain between helices 3 and 4. This hyrodphobic region is highly variable among identified Gap-like (GPL, peptidoglycolipid, addressing protein) proteins and may be involved in substrate recognition. SAP also belongs to the LysE protein superfamily (pfam01810), whose members have been implicated in small molecule transport in bacteria. Other Gap proteins export metabolites across the cell membrane so it is possible that Sap specifically may be involved in transport of sulfolipid-1 across the membrane.	1.35093e-12
NZ_CP045737.1\|WP_153653566.1\|2592744_2594499_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.23523e-113
NZ_CP045737.1\|WP_082530375.1\|2586244_2586496_+\|WhiB-family-transcriptional-regulator	gnl\|CDD\|376791	pfam02467, Whib, Transcription factor WhiB. WhiB is a putative transcription factor in Actinobacteria, required for differentiation and sporulation.	1.25978e-28
NZ_CP045737.1\|WP_153655086.1\|2588088_2588979_+\|DUF2785-domain-containing-protein	gnl\|CDD\|371322	pfam10978, DUF2785, Protein of unknown function (DUF2785). Some members in this family are annotated as hypothetical membrane spanning proteins however this cannot be confirmed. The family has no known function.	2.11979e-43
NZ_CP045737.1\|WP_153653574.1\|2595977_2596367_-\|pilus-assembly-protein	gnl\|CDD\|377921	pfam07811, TadE, TadE-like protein. The members of this family are similar to a region of the protein product of the bacterial tadE locus. In various bacterial species, the tad locus is closely linked to flp-like genes, which encode proteins required for the production of pili involved in adherence to surfaces. It is thought that the tad loci encode proteins that act to assemble or export an Flp pilus in various bacteria. All tad loci but TadA have putative transmembrane regions, and in fact the region in question is this family has a high proportion of hydrophobic amino acid residues.	6.65081e-08
NZ_CP045737.1\|WP_153653541.1\|2583373_2584342_-\|zinc-binding-dehydrogenase	gnl\|CDD\|176227	cd08266, Zn_ADH_like1, Alcohol dehydrogenases of the MDR family. This group contains proteins related to the zinc-dependent alcohol dehydrogenases. However, while the group has structural zinc site characteristic of these enzymes, it lacks the consensus site for a catalytic zinc. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site, and a structural zinc in a lobe of the catalytic domain. NAD(H)-binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	7.97723e-101
NZ_CP045737.1\|WP_153653578.1\|2597453_2598314_-\|type-II-secretion-system-protein-F	gnl\|CDD\|227300	COG4965, TadB, Flp pilus assembly protein TadB [Intracellular trafficking and secretion].	3.30385e-07
NZ_CP045737.1\|WP_153653562.1\|2589024_2590716_+\|acetolactate-synthase	gnl\|CDD\|235629	PRK05858, PRK05858, acetolactate synthase.	0
NZ_CP045737.1\|WP_153653568.1\|2594525_2595062_-\|hypothetical-protein	gnl\|CDD\|372724	pfam13779, DUF4175, Domain of unknown function (DUF4175).	0.00353989
NZ_CP045737.1\|WP_153653537.1\|2578333_2582128_+\|multifunctional-oxoglutarate-decarboxylase/oxoglutarate-dehydrogenase-thiamine-pyrophosphate-binding-subunit/dihydrolipoyllysine-residue-succinyltransferase-subunit	gnl\|CDD\|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	0
NZ_CP045737.1\|WP_153653579.1\|2598301_2599540_-\|CpaF-family-protein	gnl\|CDD\|227297	COG4962, CpaF, Flp pilus assembly protein, ATPase CpaF [Intracellular trafficking and secretion].	7.6844e-85
NZ_CP045737.1\|WP_153653570.1\|2595150_2595549_-\|hypothetical-protein	gnl\|CDD\|379164	pfam13400, Tad, Putative Flp pilus-assembly TadE/G-like. This is an N-terminal domain on a family of putative Flp pilus-assembly proteins. The exact function is not known. The Flp-pilus biogenesis genes include the Tad genes, and some members of this family are putatively assigned as being TadG.	3.389e-06
NZ_CP045737.1\|WP_153653557.1\|2584360_2585563_-\|NAD-dependent-malic-enzyme	gnl\|CDD\|223358	COG0281, SfcA, Malic enzyme [Energy production and conversion].	0
NZ_CP045737.1\|WP_153653576.1\|2596542_2597457_-\|pilus-assembly-protein-TadB	gnl\|CDD\|366122	pfam00482, T2SSF, Type II secretion system (T2SS), protein F. The original family covered both the regions found by the current model. The splitting of the family has allowed the related FlaJ_arch (archaeal FlaJ family) to be merged with it. Proteins with this domain in form a platform for the machiney of the Type II secretion system, as well as the Type 4 pili and the archaeal flagella. This domain seems to show some similarity to PF00664 but this may just be due to similarities in the TM helices (personal obs: C Yeats).	1.30651e-11

>NZ_CP045737.1|WP_153653562.1|2589024_2590716_+|acetolactate-synthase
MTTDPAGPADTTTPAPPHGGIHALDVARAHGVEQMFTLSGAHVFPLYDAAVQAEPAVPIIDVRHEPTAVFAAEAIGKLTRTPGLAVLTAGPGVTNGVSPVAQASFAGSPLVVVGGRAPNNRWGTGSLQELDQPPIFSTISKSATTARSVADIAPTIDEAFTLAGSSHRGPTFVDIPMDEFFNSAPTTYTSEGNAVSAIEPDADALREVAALLAAAERPVLVLGTDVWADRAEEAALHFVTETGIPVISNGMGRGIVPGGHPQLVTKARSTSFTRADLVIVVGTPLDFRLGYGIFGGKDGATAARTVHLADSPGQVSDHAELAGSAGGDLTTVFTTLLAALQSTSGGRPDWTPWLSTLQDEVAAATDRDRGLLSAASDPIHPARIYGELLPRLADDAVVIGDGGDFVSFAGKFVEPKRPGGWLDPGPYGCLGAGMGAAMAARIARPSSQVVLLYGDGAAGMSLMDVDTLVRHRLPVVMIVGNNSAWGLEKGPMQWLYGYDVAADLAPQTRYDQVVTALGGGGELVTDPQEIGPAIDRAFASGVPYLVNVMTDVDAAYPRATTGI
>NZ_CP045737.1|WP_153655086.1|2588088_2588979_+|DUF2785-domain-containing-protein
MQSGMAVPSHRGLDECTVELVEMLGHPNPRVREDLAYPLLTTWITRGVYDELLSGLGDGIAPGMRYGLGHDGDVSVMRRSYSALMLAEIIGRDNNEHLLPAASVLDWGDRATAWYVREQDHRGWIPEQGWANSIAHGADLLAALARSRHFARLELTVLLDVIADRVLTPTAYIWRHGEEDRLAYAVMTLLHRDALDPGIVEPWLARLGDAIRPPRTRGHLEAEWPAPAVRNTSSFLRALHLQLALGVQGRDDLRADAELFAEQPAHRADLILAVLDQIRAEQPWLYRSTTRARPLG
>NZ_CP045737.1|WP_153653561.1|2586568_2588023_-|ATPase
MPSLDDIAQFQTSLSGEDVAWLHALVTDWQIIADLSFSDLVLWVPDGEAKGMWAAAQIRPTTGATTLLEDVAGTFLPTGRGDVLEAALRSGRVVPDLVIEERDGFRVRVAVIPVSRAGRTIAVIAQRSAAAGLRTASTLESSYFEAAHELAEMIRRGEFPLPGTRSDLSDSLRVGDGFVRTDASGVVRYASPNAMSAYRRLGLSGDLVGTHLGNVTTGLVDRRPTDRGAGGLLGGDESIEAEIENSQASLLLRVIPLRSAGRRSGSLILLRDVTELRLRERELVSKEATIREIHHRVKNNLQTVAALLRLQGRRMESPEARDALEDAVRRVGSIALVHETLSQSFSDFVEFDEIADRLLHTVLDVSDGPAGANRIAAERFGSFGLLPGEVATPLAMVLTELIQNAAAHAYDEGGGTLTLAVNRIRDKVRLRVSDDGAGLPDDFDPAGSLGLSIVTTLVEGELGGTLAFEERVGGGTTVAITLVV
>NZ_CP045737.1|WP_082530375.1|2586244_2586496_+|WhiB-family-transcriptional-regulator
MDWRHKSACLDEDPELFFPIGNTGPAILQIEEAKVVCRRCDVREQCLQWALESGQDHGVWGGLSEDERRTLKRRNARARIRTA
>NZ_CP045737.1|WP_153653559.1|2585695_2586091_-|hypothetical-protein
MTSSGRPSGTARTLLLVAAAIVALEAVTFLVLAVVEAAHISGDRVGLGVGTTLFLVVIGAGLLYAARRVTEGDAWARSPLVFAQLIVLGLAYNLRGDPAWLAPVVAVPAVIALVALLSPPVTRALSRDSPV
>NZ_CP045737.1|WP_153653557.1|2584360_2585563_-|NAD-dependent-malic-enzyme
MVATDIDLQDSSFPDPDDPVFALHRGGKMSISATVDINDAHDLSLAYTPGVARVCEAIAADPDVAHDYTWVSNTVAVVTDGTAVLGLGDIGPAASMPVMEGKAILFKQFGGVDAIPVALDTTDVDEIVETIVRLAPTFGGINLEDISSPRCFEIERRLIERLDIPVFHDDQHGTAVVTLAALINAARLTDRFLEDLKIVISGAGAAGVAIMKILQSAGASRISVVDRAGVIHPGRDDLNEVKQWIATETADWARPGSIVDAMDGADVFIGVSGGTVAEEAVAKMAPDAIVFAMANPHPEVHPDVAHRHARVVATGRSDFPNQINNVLVFPGIFRGALDVRATRISEGMKLAAATAIADLVGDDLSETYVIPSPFDPRVASAVARAVTDTARREGLARRPY
>NZ_CP045737.1|WP_153653541.1|2583373_2584342_-|zinc-binding-dehydrogenase
MFAVYAGQITPDNPLDGLVVGERPEPEVPDGWTTVTVKAASINHHDVWSLRGVGLGEKSLPMILGCDAAGYDEDGNEVLVHAVISDPSWRGDETLDPKRSLLSERHQGTFAEKVAVPTRNVVPKPAGLSFAEAACLPTAWLTAYRMLFTQSGLKQGDTVLVQGAGGGVATAAITLARAAGFRVYATSRDEDKRAKAIEIGAHEAFESGARLPTKVDAVIETVGAATWSHSVKSMRPGGTIVISGATSGDAPSHAELTRIFFQQMRVHGSTMGTRDELHALAQFMDVTGTRPLIDREIPMEQAADGLQSIIDGSVFGKIVLTR
>NZ_CP045737.1|WP_153655085.1|2582666_2583290_+|AAA-family-ATPase
MSEGLDLPPGVTFLVGENGSGKSTLVEAIAIAYGLSPEGGSSHGLHQTRPTESSLHRDLLVQRGIGTRRWGFFLRAETMHGWYTYMDEHGGGDADYHAMSHGESFLEVLTRKFDSPSFYCLDEPEAALSFSSTLALIGVLHDVVQQGGQVLCATHSPVLAAMPGANILEVGNWGLRPTSWDELDLVRHWKAYLDAPMRYLRHTLAQD
>NZ_CP045737.1|WP_153653539.1|2582368_2582542_+|DUF1059-domain-containing-protein
MAKMMMCPCGQRLEGRTDDEFVSVVDTHLRDSHGGRSYPAEAILSMATSVPDETVAD
>NZ_CP045737.1|WP_153653537.1|2578333_2582128_+|multifunctional-oxoglutarate-decarboxylase/oxoglutarate-dehydrogenase-thiamine-pyrophosphate-binding-subunit/dihydrolipoyllysine-residue-succinyltransferase-subunit
MRASDNSEEAIEAVAESSQDHSTPDFGTNQWLVEEMYERYQEDPSSVDDTWVSFFQTGDGAGLNGDGPNGAAPAKAAPVVTAAPTPPPTSPESSTPPAAKTQPATASVPEEKAKDAPAPVAPVPATPPAKSKPAPSTPAAKDAPAAGPGEVENVVLRGAAARTVANMDASLSVPTATSVRSVPVKLLFDQRIVINNHLARARGGKVSFTHLIGWAIVKALKAMPEMNTGYEVVNGKPNQLKPEHINFGLAIDLKKPDGSRTLLVPSIKAADTMTFAEFWAAYETMVAKARDNKLTVADFQGTTVSLTNPGGIGTNHSIPRLMQGQGVIIGVGSMEYPPEFQGASEHTLAQMAISKMMTLTSTYDHRVIQGAQSGEFLKRIHALLLGEDGFYDEIFRALRIPYEPIRWARDIPVSHDDEVHKQARVLELIHAFRVRGHLMADTNPLDSSPRMHPDLDTASHGLTLWDLDREFATGSFKSEKRFMKLREILGILRDSYARTVGIEYMHIQEPAEREWFQERVERPHTKPPREEQLRILQKLNQAEAFETFLQTKFVGQKRFSLEGGETTIPFLDEICEAAAADKLDEVCIGMAHRGRLNALVNIAGKRPSQVFREFEGNIDPRTVQGSGDVKYHLGVEGEFTSGNGDKVKVSIAANPSHLEVVDPVLEGIARAKQDRLNRGQEYPVLPVLVHGDAAFAGQGVVAETLNLSQLRGYRTGGTIHLIVNNQVGFTTSPSSSRSSTYCTDVARMIQAPVFHVNGDDPEACIRVAQLAYEYRRTFHKDIVIDLVCYRRRGHNEGDDPSFTQPLMYDTINAKKSVRKLYTEALVGRGDITLEEAEAALTDYQAQLERNFAEVKQATSDPDYTRTPDYPEKPEHDGELITAITPETMKAIADAYTNVPEGFTVHPKVLPQLQRRAQSISAGPIDWGTGEILAMGSLLLDGRPVRLAGQDSRRGTFSSRFATIIDRNNAHEWTPLSHVGDEQATFYIYDSLLSEYAALGFEYGYSVARPEALTMWEAQFGDFVNGAQSVIDEYISAGETKWGQKSGVVLLLPHGYEGQGPDHSSGRIERFLDLCADNAMTVAQPSSPASYFHLLRRQNLQGQHRPLIVFTPKSMLRSKAAASQPEDFTSGSFRPLIGDDVADPSAVERVLLCSGRITWDLVAEREKRESGQSRTAIVRLEQIYPRPLDELKAELAKYPNLREVRFVQDEPANQGPWPHIALHFSGELDGLPLLRVSRPESSAPSVGSHNRHVEEQATLMQQAFS
>NZ_CP045737.1|WP_153653564.1|2590987_2592748_+|ATP-binding-cassette-domain-containing-protein
MVGCTWKARPLRSRRSSPQRMPETSPPSTGLRLIARSLRRHRRRLSLGFSLIMVWQMCETLVPVLIGVIVDRGIAREDGSAFLLALLGFAVLFAVLSNSYRFGGRLVVRSLEDEAHLLRTEVAGHVLHPRGARTSMLPGETLSVATSDAELVSQVMWQLAFAVSSMASVLVVAVYVLQVDLQLGLMILIGVPAVVILIQVVTPLVARRTHRQQQSTARTSGLAGDLVQGLRPLKGIGGEDVALRRYRASSQAARHDTIGVARSWGYLLGMTTGLSGILLALVTLVAGTLALDGQITLGQLIALVGLTQFLAEPISALGDISAQFAASRASAGRIADFLATPRIVPVGDRVPHGDRPQLRVDAVVDAPLDGLSFATRDGELLAITIDDPTTSDALVHLLAGTAQAATGSVTLGDVPLAELTIESRRENMLVSPHHTEIFEGTLRSAIDPDDDLTPAELDEVLAASAVDDVVALHPDGLDRPVRAGGSSLSGGQRQRVALARALAAAPPLLVLQDPTSAVDGVTEHAIAAGLRDVRGRRGHTTVVITSSPAMLQQADRVLFVQAGRVVAEGPHGQLIGDPSYREAVLR
>NZ_CP045737.1|WP_153653566.1|2592744_2594499_+|ATP-binding-cassette-domain-containing-protein
MSTQAPTHDLLPVASARDTAVLAWRMVRGRAAGLALTITSFLVVGLAGIIPVLMIGRVVDAVRDGSDASVIHRAVAVMVVSGILGGVFATLSMAALAHTVAPALAQLREDVLDRALHLETARIEAAGIGDIVSRVGDDVRHLTRALDEAIPLLINSLAAVVFTAGGLFALDWRLGLAGLGAIPCYVFALRWYLPRSAPFYARQRTADGERADALVTGVHGASTLRAFGREHDALERIDRRSQEAVDITVGVFRLYTRFGARMNSSEFVGLALVLSAGFLLVRDDAVTVGAATTAALFFHRLFNPIGALLFVFDSVQSSGAALARLAGVALIPRRPVSTQEPGPAPDLVLQGVHHAYEADREILSAIDLRIALGEHVAVVGSTGAGKTTLGSIAAGTIEPTAGTVRLGQLDLVAADEATVRRHVALVSQEVHVFAGSLRDNLVLARADADDELLWQALRRTGSEPWARALPEQLDTQVGDLGAPLSPAQAQQLALARVLLLDPQVVVLDEATAEAGSSGARELEQAALAAIAGRSAIVVAHRLAQAQSADRIVVMDRGRIVEQGTHEELVSSGGRYADLWTAWAS
>NZ_CP045737.1|WP_153653568.1|2594525_2595062_-|hypothetical-protein
MNPNDSTRENDTVIDPSNMSNQSDSTKEHSTMNEHETTTQESPKTTRSWSTRTVAVGGVVAVLLGLGAGAAIGAASGGDDEGDFGPGIARGYDGPGQMGQGPGGPGSGDGQGQMGEGQQAPDQDSDGWEHRGPGDGSRHEGGPGEGGPGEDGPDKDGRPGQQGGAQDKGGSKTDKPAA
>NZ_CP045737.1|WP_153653570.1|2595150_2595549_-|hypothetical-protein
MRREEGQITVMTIGFLVFIGLLAAVVINASAAFLERQELDNMADGAALAAADGLSRDIFYRRGEVTLDDAEARRLVGSYVTGDGIRIVRVSTDEEEVSVRLERSIDLAISPPGFTSRTTIVSEATAQLRLGD
>NZ_CP045737.1|WP_153653572.1|2595552_2595981_-|hypothetical-protein
MREREEGTATIEFVWLTLLLLVPFVYVLVAVFDTQRASFGVSTASRSAARAFLQAPDPATAEQRARLAARVALDDQGLDGASVRITCLPSPGECLQPGSSVRVVVRATQRLPLTPSSLGAQLGGVTVDSTHTEPYGSFRKEH
>NZ_CP045737.1|WP_153653574.1|2595977_2596367_-|pilus-assembly-protein
MVQRDDPDRGAAVVDFVLIMVLLVPLVLGIAQVALVLHVRNTLAAAASEGARSAAPLGATPADGAERTRTMIRTALDDRYADDVAASLTTVGGAPGTEVEVRAQVPALGLFGPSVSLTVRGHAVREVEP
>NZ_CP045737.1|WP_153653576.1|2596542_2597457_-|pilus-assembly-protein-TadB
MSGALVGFCLSAGLVLIVSGWLRTRRPSLDQRVLPYVRDVHPSPAAPGPAGPLLDAVLGPALQRLGTVVGDLVGGSASVSRRLVRLGSPRSVDDFRITQVMWGAAGLAVGAGVSAVLWSSRGTPVPLLLVVSAMGFVVGVLWCDSHLSSKVTAREREMQAEFPVVADLLALAVAAGESPIAGLERILKVCHGALTDELARVISDVRTGTPMAEAFDRLAARTGVTSIARFAEGLAIAVERGTPLVDVLHAQAADVRESGRRELIEAGGRKEVAMMIPVVFLILPVTVVFAFFPGYVGLHLTSGT
>NZ_CP045737.1|WP_153653578.1|2597453_2598314_-|type-II-secretion-system-protein-F
MGALIGLVAGAGILLVLWTFAEPDWQPTRRTSARRHPVADLLAAAGVVGVSPGQLVATCVVAFVVGAVVMTGVSGVVAIGVVFGAMAGALPVGVLRGRAIRRLRDHAALWPDAVDNLASAVRAGLSLPEALIQLGERGPEAMRDAFVQFGRDYHGTGRFNDSLDRLKDRLADPVGDRVIEALRIARDVGGGDLGRMLRSLSGFLREDLRTRGELESRQSWTVNGARLAVAAPWLVLLLMCLQGDVVGRFASGAGLVVLTTGAVLCVVAYRLMMWIGRLPTERRILA
>NZ_CP045737.1|WP_153653579.1|2598301_2599540_-|CpaF-family-protein
MESSTSALADRVRDLVRQRRIDPRTDTASVRLAAIDAIAEHEARSLTGAVRTLDEPEVVIGQIVADVSGFGPLQAYLDDDTVEEVWINEPSRVFIARAGRHELTSLILSAELVRELVERMLSTSGRRLDISQPFVDAMLPGGHRLHVVLDGIARGFAAVNIRKFVAKAHSLDDLVALGTLDPPSAAFLDASVRAGLNIVVSGGTQAGKTTLLNCLAASIPGSQRLVSVEEVFELQCGHPDWVAMQTRQAGLEGTGAIDLRMLVKEALRMRPSRIVIGEVRAAECLDLLLALNAGLPGMASIHANSARQALVKLCTLPLLAGDNIGSRFVVPTVAAAVDIVVHTGLDPDGSRAVREIVAVTGRVENDLIESDPVFARQDGRLVRGHGAPLRREAFEQAGIDLDAVLGVTRWAP
>NZ_CP045737.1|WP_153653581.1|2599673_2600480_-|hypothetical-protein
MRVDDREQSTSPTRRFRWTRVGRVRQAMGDEDGQRSKTQAPHRRGYAFCLMISVLVLVIPLALAGAVSPVMLTEQTVLLAGRDGRRVAGCYAIGVGGTFLVLLWLMVAFGHSIALPKEPRLSASLDLVLGLLLILIAALLRYRRRRAPKAKKPRDYGLGLVQAFGFGVFSMATNFTTLAIMVPVAKEISASHLDVLGRLTVVCIVAVVGALPAWLPLAMTLVAPDPTRRGLQVLSDFIDRRGPLITILLLAAAGIFLVIRGLIHMIGL

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP045737_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045737_11

3290928-3291025

Orphan

Consensus_repeat	Method
GGGACGGACGATGAGGGTTTGCGGCAGCTGTGAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045737_11

>merge|NZ_CP045737|11|3290928-3291025|CRISPRCasFinder
GGGACGGACGATGAGGGTTTGCGGCAGCTGTGACCACCCCAAACGCTCATCCTGGGTCGTACCCGGGACGCACGATGAGGGTTTGCGGCAGCTGTGAC

>NZ_CP045737|11|11|3290928-3291025|CRISPRCasFinder
GGGACGGACGATGAGGGTTTGCGGCAGCTGTGAC	CACCCCAAACGCTCATCCTGGGTCGTACCC
GGGACGCACGATGAGGGTTTGCGGCAGCTGTGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045737.1\|WP_153654588.1\|3285232_3286588_+\|type-VII-secretion-integral-membrane-protein-EccD	unknown	unknown	gnl\|CDD\|274855
NZ_CP045737.1\|WP_153654591.1\|3289948_3290908_+\|zinc-binding-dehydrogenase	unknown	unknown	gnl\|CDD\|176203
NZ_CP045737.1\|WP_153654595.1\|3294664_3295057_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133384
NZ_CP045737.1\|WP_153654596.1\|3295171_3296986_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|132997
NZ_CP045737.1\|WP_153654587.1\|3283841_3285236_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237537
NZ_CP045737.1\|WP_153655137.1\|3293090_3293669_+\|TIGR02453-family-protein	unknown	unknown	gnl\|CDD\|378166
NZ_CP045737.1\|WP_153654598.1\|3299337_3300717_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|223605
NZ_CP045737.1\|WP_153654590.1\|3288703_3289915_+\|S8-family-serine-peptidase	unknown	unknown	gnl\|CDD\|274856
NZ_CP045737.1\|WP_153654597.1\|3297809_3299255_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_CP045737.1\|WP_153654594.1\|3293670_3294657_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381302
NZ_CP045737.1\|WP_153654584.1\|3281663_3281966_+\|WXG100-family-type-VII-secretion-target	unknown	unknown	gnl\|CDD\|274862
NZ_CP045737.1\|WP_153654582.1\|3279828_3281217_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274855
NZ_CP045737.1\|WP_153654589.1\|3287345_3288707_+\|type-VII-secretion-protein-EccB	unknown	unknown	gnl\|CDD\|368288
NZ_CP045737.1\|WP_153654583.1\|3281334_3281649_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377587
NZ_CP045737.1\|WP_153654599.1\|3300745_3301198_+\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180
NZ_CP045737.1\|WP_153654585.1\|3281972_3282581_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045737.1\|WP_153655138.1\|3296995_3297643_-\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|367243
NZ_CP045737.1\|WP_153654586.1\|3282577_3283855_+\|S8-family-serine-peptidase	unknown	unknown	gnl\|CDD\|173787
NZ_CP045737.1\|WP_153654592.1\|3291063_3292068_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381302
NZ_CP045737.1\|WP_153654593.1\|3292169_3293009_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|375319

Protein	Function_ID	Function_description	E-value
NZ_CP045737.1\|WP_153654588.1\|3285232_3286588_+\|type-VII-secretion-integral-membrane-protein-EccD	gnl\|CDD\|274855	TIGR03920, T7SS_EccD, type VII secretion integral membrane protein EccD. Members of this family are EccD, a component of actinobacterial type VII secretion systems (T7SS) with ten to eleven predicted transmembrane helix regions. [Protein fate, Protein and peptide secretion and trafficking].	2.32689e-19
NZ_CP045737.1\|WP_153654591.1\|3289948_3290908_+\|zinc-binding-dehydrogenase	gnl\|CDD\|176203	cd08241, QOR1, Quinone oxidoreductase (QOR). QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR acts in the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site, and a structural zinc in a lobe of the catalytic domain. NAD(H)-binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	6.14724e-139
NZ_CP045737.1\|WP_153654595.1\|3294664_3295057_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133384	cd01109, HTH_YyaN, Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB. Putative helix-turn-helix (HTH) MerR-like transcription regulators of Bacillus subtilis, YyaN and YraB, and related proteins; N-terminal domain. Based on sequence similarity, these proteins are predicted to function as transcription regulators that mediate responses to stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	9.87434e-46
NZ_CP045737.1\|WP_153654596.1\|3295171_3296986_+\|glycosyltransferase	gnl\|CDD\|132997	cd00761, Glyco_tranf_GTA_type, Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.	4.28876e-22
NZ_CP045737.1\|WP_153654587.1\|3283841_3285236_+\|hypothetical-protein	gnl\|CDD\|237537	PRK13875, PRK13875, conjugal transfer protein TrbL; Provisional.	2.79638e-11
NZ_CP045737.1\|WP_153655137.1\|3293090_3293669_+\|TIGR02453-family-protein	gnl\|CDD\|378166	pfam09365, DUF2461, Conserved hypothetical protein (DUF2461). Members of this family are widely (though sparsely) distributed bacterial proteins, about 230 residues in length. All members have a motif RxxRDxRFxxx[DN]KxxY. The function of this protein family is unknown.	1.40451e-64
NZ_CP045737.1\|WP_153654584.1\|3281663_3281966_+\|WXG100-family-type-VII-secretion-target	gnl\|CDD\|274862	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target. Members of this protein family include secretion targets for the two main variants of type VII secretion systems (T7SS), one found in the Actinobacteria, one found in the Firmicutes. This model was derived through iteration from pfam06013. The best characterized member of this family is ESAT-6 from Mycobacterium tuberculosis. Members of this family usually are ~100 amino acids in length but occasionally have a long C-terminal extension.	1.61147e-13
NZ_CP045737.1\|WP_153654590.1\|3288703_3289915_+\|S8-family-serine-peptidase	gnl\|CDD\|274856	TIGR03921, T7SS_mycosin, type VII secretion-associated serine protease mycosin. Members of this family are subtilisin-related serine proteases, found strictly in the Actinobacteria and associated with type VII secretion operons. The designation mycosin is used for members from Mycobacterium. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair].	1.27e-67
NZ_CP045737.1\|WP_153654597.1\|3297809_3299255_+\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	3.53403e-44
NZ_CP045737.1\|WP_153654594.1\|3293670_3294657_-\|aldo/keto-reductase	gnl\|CDD\|381302	cd19076, AKR_AKR13A_13D, AKR13A and AKR13D families of aldo-keto reductase (AKR). Schizosaccharomyces pombe aldo-keto reductase YakC is a founding member of aldo-keto reductase family 13 member A1 (AKR13A1). It catalyzes the reversible reduction of ketones to the respective alcohols using NADP(+) as a hydride donor. Rauvolfia serpentina PR is a founding member of aldo-keto reductase family 13 member D1 (AKR13D1). It catalyzes the NADPH-dependent reduction of the aldehyde perakine to yield the alcohol raucaffrinoline in the biosynthetic pathway of ajmaline in Rauvolfia, a key step in indole alkaloid biosynthesis. This family also includes Arabidopsis thaliana aldo-keto reductases, ALKR1-6.	1.75285e-171
NZ_CP045737.1\|WP_153654582.1\|3279828_3281217_+\|hypothetical-protein	gnl\|CDD\|274855	TIGR03920, T7SS_EccD, type VII secretion integral membrane protein EccD. Members of this family are EccD, a component of actinobacterial type VII secretion systems (T7SS) with ten to eleven predicted transmembrane helix regions. [Protein fate, Protein and peptide secretion and trafficking].	0.000714806
NZ_CP045737.1\|WP_153654592.1\|3291063_3292068_-\|aldo/keto-reductase	gnl\|CDD\|381302	cd19076, AKR_AKR13A_13D, AKR13A and AKR13D families of aldo-keto reductase (AKR). Schizosaccharomyces pombe aldo-keto reductase YakC is a founding member of aldo-keto reductase family 13 member A1 (AKR13A1). It catalyzes the reversible reduction of ketones to the respective alcohols using NADP(+) as a hydride donor. Rauvolfia serpentina PR is a founding member of aldo-keto reductase family 13 member D1 (AKR13D1). It catalyzes the NADPH-dependent reduction of the aldehyde perakine to yield the alcohol raucaffrinoline in the biosynthetic pathway of ajmaline in Rauvolfia, a key step in indole alkaloid biosynthesis. This family also includes Arabidopsis thaliana aldo-keto reductases, ALKR1-6.	3.1637e-131
NZ_CP045737.1\|WP_153654589.1\|3287345_3288707_+\|type-VII-secretion-protein-EccB	gnl\|CDD\|368288	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B. EccB is a family of largely Gram-positive bacterial transmembrane componenets of the type VII secretion system characterized in Mycobacterium tuberculosis, systems ESX1-5. Translocation of virulent peptides through the membranes is thought to be mediated via a complex that includes EccB, EccC, EccD, EccE, and MycP. EccB, EccC, EccD, and EccE form a stable complex in the mycobacterial cell envelope.	4.48484e-50
NZ_CP045737.1\|WP_153654598.1\|3299337_3300717_+\|amino-acid-permease	gnl\|CDD\|223605	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism].	3.40163e-45
NZ_CP045737.1\|WP_153654583.1\|3281334_3281649_+\|hypothetical-protein	gnl\|CDD\|377587	pfam06013, WXG100, Proteins of 100 residues with WXG. ESAT-6 is a small protein appears to be of fundamental importance in virulence and protective immunity in Mycobacterium tuberculosis. homologs have been detected in other Gram-positive bacterial species. It may represent a novel secretion system potentially driven by the pfam01580 domains in the YukA-like proteins.	0.000215984
NZ_CP045737.1\|WP_153654593.1\|3292169_3293009_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|375319	pfam17765, MLTR_LBD, MmyB-like transcription regulator ligand binding domain. This domain is found in a family of actinobacterial transcription factors. The structure shows it has a PAS domain like fold and it is bound to Myristic acid.	2.13744e-41
NZ_CP045737.1\|WP_153655138.1\|3296995_3297643_-\|TetR-family-transcriptional-regulator	gnl\|CDD\|367243	pfam02909, TetR_C, Tetracyclin repressor, C-terminal all-alpha domain.	7.21547e-08
NZ_CP045737.1\|WP_153654586.1\|3282577_3283855_+\|S8-family-serine-peptidase	gnl\|CDD\|173787	cd00306, Peptidases_S8_S53, Peptidase domain in the S8 and S53 families. Members of the peptidases S8 (subtilisin and kexin) and S53 (sedolisin) family include endopeptidases and exopeptidases. The S8 family has an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. Serine acts as a nucleophile, aspartate as an electrophile, and histidine as a base. The S53 family contains a catalytic triad Glu/Asp/Ser with an additional acidic residue Asp in the oxyanion hole, similar to that of subtilisin. The serine residue here is the nucleophilic equivalent of the serine residue in the S8 family, while glutamic acid has the same role here as the histidine base. However, the aspartic acid residue that acts as an electrophile is quite different. In S53, it follows glutamic acid, while in S8 it precedes histidine. The stability of these enzymes may be enhanced by calcium; some members have been shown to bind up to 4 ions via binding sites with different affinity. There is a great diversity in the characteristics of their members: some contain disulfide bonds, some are intracellular while others are extracellular, some function at extreme temperatures, and others at high or low pH values.	6.29039e-28
NZ_CP045737.1\|WP_153654599.1\|3300745_3301198_+\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	6.72362e-22

>NZ_CP045737.1|WP_153654591.1|3289948_3290908_+|zinc-binding-dehydrogenase
MKAIQITTLDGPTAVELLDVPDPVPADGQVLIRVHAAGVAFPEVLQTRGLYQVKPDLPFTPGAEIAGEVLSAPEGSGLVAGDRVAALCLLGGFAEQAVAPVSETFKLPDSVSYEQGASFIFNYGTAYFALIERGHLQPGESVLVHGAAGGVGTAAIQVAKAFGAGRVVAVTSTAEKGAVALEAGADEFVLADGFKDATVARGKVDVVVDPVGGDRFTDSLRCLAENGRLLVIGFTAGEIPTVKVNRLLLNNVSVVGVGWGASVLARPGAIAAEWDAMEPHLASGALRPVIGPTFPLAEATQALLTLDERRATGKVLLTL
>NZ_CP045737.1|WP_153654590.1|3288703_3289915_+|S8-family-serine-peptidase
MRRALPMALLVLAGSVALPAVAVSPAAAQTTDDGKCTVGKTKWVTDAAANANLVQTGFTESWKLATGKGTVVAVVDSGINADNPHFDGVIVGQKSFVGGSGTDDQQGHGTAVAGIIRARQLKKKSVLTGAAPDAKLLSVRVNLLNDEISTANVARGIRWAAEQDEVDVINVSISTGPGDPDLKELESAVAFAVRKDIVVVAAAGNKPGDPQVPYTQVQYPAGFDGVLGVAAARPEGGVDNWSIRGRHVDVSAPGANVPTTFHANGDCLVGLDHPYTSYSTPYVSALAAQLRERFPKDSAAQIINRITSTADRPRMATRNDREGWGRIQPVAALTSSSAAPPSKRTSTVPQTTGTGIRPTAVVADPMAGPRNRLLWWGLGATVLLAVALVARPLSERRRTRSNR
>NZ_CP045737.1|WP_153654589.1|3287345_3288707_+|type-VII-secretion-protein-EccB
MASKRDLVEAHDFNRRRLVTAFLSGAPGGREVEPVRYGRTIIGGLVLAGILVAGAAVTGVLKPTVSDDWRDNGLVIGKESGSRFLMYNDELFPVANIASARLALRDEPKISYVPDDILVKEPKRNAIGILNAPDYLPPANRLVQDGWTACTNTDGGLRTVVDTTPGAKRSSGSALVVRSRDDAKYWIVADGYRYPVPPDGETGRAILRALALDRTTAFPAPNSWLELLPVASPIQAFSVPGTGQPFRQGRQAIEGLDTIGTPVDVDGRKYVLAEGGLVPLTDFAYQIYLVSPNGQSEPRNLDPADFGSLNTLPNETPYPRDWPDDVPSSYTESTPCLILERGEDATTTSGAYLASSTDPSVLPNGSAVTTDVQQGRGALVYGTTRPQGGPVDTEFLIDSLATRYAIEPKNSVDEAQKRLGYGGVTPVPVPRAWTELFRDGPSLDVERAGAPVG
>NZ_CP045737.1|WP_153654588.1|3285232_3286588_+|type-VII-secretion-integral-membrane-protein-EccD
MTSSTAVHSLGGLVRVTIASGDRRTDLALPSSVTVAELLPELARSMGVLEPGSAHTGFRLLAADGTQLSASAGLAFQNVYDGAVLTLAPGHEDSPRVYDDVVEAMSDVIEETTRPWEPTAARNTALIASGSLLALGALSIGVERTSILAGALAGGIALVLLTASIVVSRLEHENEIALMLGWSAVVYAAVGAFTAVSSDEILGAPLASAGGAGAVTAILAMAGLESRRLLMLPGVILGVIAAAASGLVIATDLEPAKIYLVALALAVIASGVQPALALTSAGASSPQPEDPASLPDDPSEVDIEKVRTGARVGHDVLLATTVTSGLLLIAVAPLAVTLGLTGMLTTVAAAVALLVRTRQFRSGTEVGAGLLTAAAGILSIAISVLVLEPDWRPGLIVVLIVVAAGTLVSTLVTSTRTVSRGRMAEVLELIALVAIVPLLVIAIGIVSAVRS
>NZ_CP045737.1|WP_153654587.1|3283841_3285236_+|hypothetical-protein
MGPNEAKLQEIAATAPHNASSKKRAWKSSYAKVTEIIDELDAQASRTRKAWTGADADAAAAAFEKKRQQLEEYRDQMEKSALAMEEARHGLALAEKNLGALPPVGSPPGSAPASLDAGADDDAIKEHKADVKKHDAAVSAHDAALKERERKAGEALDSFDASMKVAQALLSKAAPIGKNPVDDDKPHPTRGGSGSGGSGGSGSGGSGNPVVGGSTAAASMLSASGHSGSSSWAIGGLHPGALLTPGDPGPGPGVAGEPGDPGAGGVGSGGGSGAPGGTAGGAAASAGTIGGGGAGAAASAAGALGAGRGLLNRLTGGASAAGSAAPGRTAGMQNGSTLGARSAGAAGAASSSGAQSGGAQSSAGRPGGAQSSAGRAGGAQSSAGRPGGAQSGAGRSGAGSPAGARGTGSGSRGAAGARGAAGAGAGAGRSGQRPGDNNDQLVDHMAFDDDQWLDDDDTTPGVIA
>NZ_CP045737.1|WP_153654586.1|3282577_3283855_+|S8-family-serine-peptidase
MTIRGRGGAAVAAALVLLTLATPPASAKPLEPWWFTSLSVASNHEQSTGKGVKIAVIDGALNRDIPELDGAKVKLRAALAPGLKSGLIKPRSFSREFYASHGTAMTTLIVGQGKGNAPGGAGITGMAPDAEVYFYQMDPDPTDPETPYPGELFEQAIKDKVDIISYSFTNSTMLEPQIEAAQAAGIVVVAGAGNPNAAVTEPASLPGVVAVGVLDKKIRPWKKQPEGNITIIAPGVDIASGAMKGTATQARWVSGVERTGTSDATPLVAGALALVKSKYPHATGNQLIQQLIHSAGGRDYGYSMEGGFGVISLEELLARDPAGWPDENPLLKGPNYAFDTYPQSAWKDPDAPTPKPTPADTNDKPAADQSAQPAAEDESSSPLPWIIGAAVLVALLVVAAAMARRRRGVSSALTTKTGGTSDGTQ
>NZ_CP045737.1|WP_153654585.1|3281972_3282581_+|hypothetical-protein
MDPDARLGTAPAFGGSGSGAHIELTIEEVEKIGRATAALNERAQAARTELADAAGGGGFSSYPSAQALFDQHQAVVEVFDKTLAAMTTDLDDFGSTIVQAAHNHDQTDNDVLATMAMIAAKVDTASLIKAHEQARNEAGHRLQEPDTDLDTTPEIDAFDEENPSVKEPSLDGLRSEEAPSIPTFGEDQGEDALFDASGGAPK
>NZ_CP045737.1|WP_153654584.1|3281663_3281966_+|WXG100-family-type-VII-secretion-target
MTGNTGRLAVSFGGLGNLAGEVAAGVAKLEARLNQLDQDLTPLKGDWTGEAAASYQQAKAKWDQAIQDLKLTLSQSGQAVNDSGEDYRRTETQNASSFGG
>NZ_CP045737.1|WP_153654583.1|3281334_3281649_+|hypothetical-protein
MTDLSREEMALTKAAGLVRDAHGELNTEVGNMPTRLQTKGSWEGGGSESFTGLINAWTRETNHILKALEVFDANLTGADKAYTTTDQAQQDKYTQIANRMTTQG
>NZ_CP045737.1|WP_153654582.1|3279828_3281217_+|hypothetical-protein
MTDSIVHATVRLTILGDGGRVDVAVPLWTEISSLAHMYAERTDGGPAVLHSAAGRGLAPRDTVHGVGLTHGDVLVAIAGTGQPGQPVRETAEETTGDAPAPRSEGRRAVMMPLATGAAGIFAAVAGTLEGGTAADAATAALLVIALLAVLLARGERRVDRAWLSVVPLLVAAGAATVTMATLDDGDVGDVLLVAAVSGLVAAASAAVVRSGSPRIADDWLLGWMVTGCVVAGCAAACLLMEWSTTTFWVLLLTLATVSTRLVPARVVEVPDHVLLDFARLAVTAWTAREQPRRSFRGVIRRDDVESVARRALRLVDAASVFGAVAVVVATVALLLGDHGTSRRIGIILLCVGVGGSFTLGGRALRIRTARRAQRSAGTIVLVLVTIYAFDQLGDSIRPFVTAAIVALGMLLVVVARAVSRGWSSVRWSRTAETAETFAGILVYGSLPLATGLFDWMRILTSP
>NZ_CP045737.1|WP_153654592.1|3291063_3292068_-|aldo/keto-reductase
MTTQTRATKTLGTLGTTPAMGLGLMGMSALYGPADRDESIATIRAAIDAGIRLLDTGDFYAMGHNEMLLRDALTGVDRDSVDISVKFGALRGPDGGWYGFDARPGAVKTFLAYSLERLGTDHVDVYRPARLDPDVPIEDTVGAIAEMVEAGFVRHIGLSEVGAETIRRAHAVHPISDLQIEYSLVSRGVEGDILDTCRELGIGITAYGVLSRGLISGHYSRDNVQANDFRSHSPRFQGDNLDRNLALVETLRAVAADSGVSVAQAAIAWVASRGDDIVPLVGARTRERLAESLGAVGVELGEEQLAAIEAAMPAGEVAGTRYASEQMAMLDSER
>NZ_CP045737.1|WP_153654593.1|3292169_3293009_+|helix-turn-helix-domain-containing-protein
MEREALADFLVRRRDALQPGDVGLTAGPRRRAPGLRREEVAQLTGMSVDYYARLEQGRSPQPSTQMLRALARTLRLSRDESDHLHRLAGHPAPDRVSVSSHVRPVLLHVLDQLEDCVAFVCSDTDVVLAQNRLSLLLQGDHRGRTGVEASSTYRWFTQPGAQDQALPEDRAEHSRVRVADLRATWSRRRHDADVTELVDALLAQSPEFAEIWARHEVGVRHMRTKRFNHPQVGVLEVDCETMATGEDGQRLVILGAAPGTEAHGKLRLLAVLGQQSVDA
>NZ_CP045737.1|WP_153655137.1|3293090_3293669_+|TIGR02453-family-protein
MDNTKTFWEAHKEVYATAVAAPMRALVAALADEFGEARIYRPYRDVRFAKDKTPYKTHQGAFVAKGPSTGYYVQVGAPGVRVGSGFYEASPARLASIREAIVDDRRGRELEEILAALRSSGWEIGGNRLKTSPRGYDADHPRIDLLRHKSMNVGKSYGFEPVIHTPELVDRVRADWREVTPLVEWFLRYARG
>NZ_CP045737.1|WP_153654594.1|3293670_3294657_-|aldo/keto-reductase
MKTTAWGSQGLEASVEGLGAMGMSAFYGARDDEESAATLNRALDLGVSLIDTAEMYGPFLNEQLIARTIGSRKDEYALATKTGVEIGDHGERVGPNGSPAYLRKALERSLRNLDRETIDLYYIHRVDPDTPIEETFGALSEFVQEGKVRYLGISEASPETIRRAHATHPLTAVQTEYSLFERSPEVNGVLDTTRELGIAFVAYSPLGRGLLTGKIASADDLDADDFRRTSPRFADENLAANLSVVDRVRALAEGKGVTPGQLALAWVLHQDGVVAIPGTKRRTYLEENVAAADIELTADDLATLDEAAPVGVTAGERYPEAALKGLTI
>NZ_CP045737.1|WP_153654595.1|3294664_3295057_-|MerR-family-transcriptional-regulator
MTVTEVPPEGLTISAAAEMSGLSIDTLRYYEKEGLTLHRPGRSPSGQRRYSEDNLRWLATLVMLRRTGMPIRDIKRFVELYRVDGSEADRLAILEAHRVHVLEQLAEVQTHLEAINRKIDYYTSAVTEGK
>NZ_CP045737.1|WP_153654596.1|3295171_3296986_+|glycosyltransferase
MSAKVAVVVPIHDQEAWLPAALESLRHQRFTDWECVIVADGSPGDTAAAAAAILDDPRVTLVEDAANRGLGAALNRGLDLTSAPLVAYLPADDVMHAEHLAALVEALEADPTAPLAVTGLRHDTDRTSTGRIEGEPLQLVQVMHRRTADRWVERDELTTDDLDRMLWDRLLTAGPAATTGRVTATWSSHPGQRHRLMREPWGGINPYRSRYGVTAPLRFHSTAGHLHDEVEHYRTFRERPRTPHTPDGLRILLVGELAHNPDRVLTLAERGHELHGLWTDRPLWFNTVGPLPFGHVSEVPREGWRDAVRELAPDVIYGLLNWQAVPFVHEVLSADLGIPFVWHFKEGPWFSREHGHWPMLVDLHTRTDGVIYSSPELRDWFHATVPASRTRPSCIVDGDLPKAEWLMGEQSPRLSERDGQLHTVIAGRPMGPPPEVVEELARHDVHLHVYSEKGHAQMREWVTEVRRVAPHHLHLHPQVDQEDWVAEFSQYDAGWLHDVRSTNGGDLHAATWGDLNYPARIGTYAAAGVPMIQRDSHGSIVASEQLIRDLDLGFTWREPSDLLQSLQDAERLDRLRKSVWSQRDRFTFDAHTDQIVSFLRARSS
>NZ_CP045737.1|WP_153655138.1|3296995_3297643_-|TetR-family-transcriptional-regulator
MEAVLNEAVSLLDEAGVPALTFRALAGRLGGGVGSIYWYVSGKDELLDLATDHAVGPLLAELEARPDADDPIDELRTMAVRMFDAIVVRPWLAAYFMRNSLLQPNTMRLYERLGQVTLRLDLTPRQRFHAVSAIVGYTVGTAADLGQEPPREVVDGEVGREEYLARFADLWRGLDPEQYPFVHQIADEFAHHDDKDQFRAGLDLLLAGLRLEAEG
>NZ_CP045737.1|WP_153654597.1|3297809_3299255_+|MFS-transporter
MSTTSSPTRTYSSLRSAWIPLTALCLAFFVEMVDNTLLTIALPTIGRDLGGGTTALQWVTGAYSLTFGGLLLTAGSMADRLGRRRVLLVGLAAFGLISLCVVAVSTTGELIALRAVLGLAAAAMAPITNSLVFRLFDDQALRMRAMTLMIVVGMSGFILGPVLGGTALAHVRWEWLLVVNAPLALIAAIGVRLGVSPDRRDDLTDDALDLPGAALSIAAIGLACYCLTSGVEHGWLSAVTLSSIIGAVAAAIAFVRHESRTPAPMLDLTLFRNGTLRGAALAQIGTSIAMASVMFGLILHFQYAYGWSPMRAGLANLPIIVTMIAATPVSEWLARRFGHRIACLLCSALMAGSLAGLAWGVDHGYAPIAVAMVVMTIGMRTVMTICAVALVEAMPANRTSIGTALNDTAQEVGASVGTAAVGTLIAVLVTSRLPAGTWSSELVASFFHGERITYAVLAAVVGLLAAAGALTLTDSRSTDEH
>NZ_CP045737.1|WP_153654598.1|3299337_3300717_+|amino-acid-permease
MTDQSAAPQTQDEPEGELQRSITGRLLFFYVLGDVLGSGIYALIGVMAFTVGGAFWISFAVGVTIALLTGFAYAELITKYPQAAGAALYAHKAFGNRAVTFLVAFCLLAATIAAAGTLARVFGGIYFKEFVDGIPVAVVAIAFIVVLSLLNFRGITESVWANMVMTLIETTGLLIILVIGGTVLAEGDADLATPFELNDGNPGLVVLSGVALAFFAMTGFENAANIAEETREPSKVFPRALLGGMALAGVLYIVIAFIAAMVTPLADLTADEGESGSLLTVVQAGPLAIPELVFSAIALVAVTNTTLVSLVAQSRIMYGMARQGVLPRVFARTHSSRHTPWVAIIFTSALVCLLLVTADVDRLATVTVLFLIVVYAMVCVSALKLRGSDVDHDHYTAPTALLWIGAAANAGILVHTVIDDPGSLIWCGGILAVGVVLYFLNNAVMKRSSPHVDDPVSPS
>NZ_CP045737.1|WP_153654599.1|3300745_3301198_+|universal-stress-protein
MHVIIATDGSQQSLRATRYLRSFADSEAITSVGIVAVLSPLAAVPFAGDATSEKNEAAEVSFRDAAKQATREAAALLEGWGPKVTTHVRSGNPATEIVRAAKAKKAGLIVIASQSSRAEAVLMGSVAHKVLNHATCPVLVVRPGAKNKRK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP045737_3	3.1\|855986\|29\|NZ_CP045737\|CRISPRCasFinder	855986-856014	29	NZ_CP045737.1	853553-853581	1	0.966
NZ_CP045737_3	3.1\|855986\|29\|NZ_CP045737\|CRISPRCasFinder	855986-856014	29	NZ_CP045737.1	987660-987688	1	0.966
NZ_CP045737_10	10.1\|2590761\|29\|NZ_CP045737\|CRISPRCasFinder	2590761-2590789	29	NZ_CP045737.1	2441675-2441703	2	0.931

1. spacer 3.1|855986|29|NZ_CP045737|CRISPRCasFinder matches to position: 853553-853581, mismatch: 1, identity: 0.966

ctgcgtccccccggcgcgggcgcgggacg	CRISPR spacer
ctgcgtcccccgggcgcgggcgcgggacg	Protospacer
*********** *****************

2. spacer 3.1|855986|29|NZ_CP045737|CRISPRCasFinder matches to position: 987660-987688, mismatch: 1, identity: 0.966

ctgcgtccccccggcgcgggcgcgggacg	CRISPR spacer
ctgcgtccccccgacgcgggcgcgggacg	Protospacer
*************.***************

3. spacer 10.1|2590761|29|NZ_CP045737|CRISPRCasFinder matches to position: 2441675-2441703, mismatch: 2, identity: 0.931

cggccgacgagtcacgcacggcggccgac	CRISPR spacer
cggccgacgagtcacgcacggacgccgac	Protospacer
*********************  ******

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP045737_3	3.1\|855986\|29\|NZ_CP045737\|CRISPRCasFinder	855986-856014	29	NC_014718	Paraburkholderia rhizoxinica HKI 454 plasmid pBRH01, complete sequence	63725-63753	6	0.793
NZ_CP045737_3	3.1\|855986\|29\|NZ_CP045737\|CRISPRCasFinder	855986-856014	29	NZ_LN832562	Paracoccus aminovorans isolate JCM7685 plasmid IV, complete sequence	531833-531861	6	0.793
NZ_CP045737_3	3.1\|855986\|29\|NZ_CP045737\|CRISPRCasFinder	855986-856014	29	NZ_CP047040	Rhodobacter sphaeroides strain 2.4.1 substr. H2 plasmid pB, complete sequence	7541-7569	6	0.793
NZ_CP045737_3	3.1\|855986\|29\|NZ_CP045737\|CRISPRCasFinder	855986-856014	29	NZ_CP040819	Paraoceanicella profunda strain D4M1 plasmid pD4M1A, complete sequence	104707-104735	7	0.759
NZ_CP045737_3	3.1\|855986\|29\|NZ_CP045737\|CRISPRCasFinder	855986-856014	29	NC_016586	Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence	126577-126605	7	0.759
NZ_CP045737_3	3.1\|855986\|29\|NZ_CP045737\|CRISPRCasFinder	855986-856014	29	NZ_CP023039	Komagataeibacter saccharivorans strain CV1 plasmid unnamed3, complete sequence	6541-6569	8	0.724
NZ_CP045737_3	3.1\|855986\|29\|NZ_CP045737\|CRISPRCasFinder	855986-856014	29	NZ_AP014706	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence	360644-360672	8	0.724

1. spacer 3.1|855986|29|NZ_CP045737|CRISPRCasFinder matches to NC_014718 (Paraburkholderia rhizoxinica HKI 454 plasmid pBRH01, complete sequence) position: , mismatch: 6, identity: 0.793

ctgcgtccccccggcgcgggcgcgggacg	CRISPR spacer
cgacgtccccccggcgcgagcgcgacacc	Protospacer
* .***************.*****. **

2. spacer 3.1|855986|29|NZ_CP045737|CRISPRCasFinder matches to NZ_LN832562 (Paracoccus aminovorans isolate JCM7685 plasmid IV, complete sequence) position: , mismatch: 6, identity: 0.793

ctgcgtccccccggcgcgggcgcgggacg	CRISPR spacer
acgcgaatccccggcgccggcgcgggacg	Protospacer
 .***  .********* ***********

3. spacer 3.1|855986|29|NZ_CP045737|CRISPRCasFinder matches to NZ_CP047040 (Rhodobacter sphaeroides strain 2.4.1 substr. H2 plasmid pB, complete sequence) position: , mismatch: 6, identity: 0.793

ctgcgtccccccggcgcgggcgcgggacg	CRISPR spacer
ccgcgtcaccccggcacgggcgcggtgca	Protospacer
*.***** *******.********* .*.

4. spacer 3.1|855986|29|NZ_CP045737|CRISPRCasFinder matches to NZ_CP040819 (Paraoceanicella profunda strain D4M1 plasmid pD4M1A, complete sequence) position: , mismatch: 7, identity: 0.759

ctgcgtccccccggcgcgggcgcgggacg	CRISPR spacer
ccccggccgcccggcgcgggcgcgggcga	Protospacer
*. ** ** *****************  .

5. spacer 3.1|855986|29|NZ_CP045737|CRISPRCasFinder matches to NC_016586 (Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence) position: , mismatch: 7, identity: 0.759

ctgcgtccccccggcgcgggcgcgggacg	CRISPR spacer
cggcgtccccccggcgggggcgccgccgc	Protospacer
* ************** ****** *

6. spacer 3.1|855986|29|NZ_CP045737|CRISPRCasFinder matches to NZ_CP023039 (Komagataeibacter saccharivorans strain CV1 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.724

ctgcgtccccccggcgcgggcgcgggacg	CRISPR spacer
gcccgtccccccggcccggtcgcggggga	Protospacer
 . ************ *** ******. .

7. spacer 3.1|855986|29|NZ_CP045737|CRISPRCasFinder matches to NZ_AP014706 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence) position: , mismatch: 8, identity: 0.724

ctgcgtccccccggcgcgggcgcgggacg	CRISPR spacer
tccggtcccccccgcgcgggcgcggcctg	Protospacer
..  ******** ************  .*

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage