CRISPRimmunity

Please click to download your results

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP045920	Pseudactinotalea sp. HY158 chromosome, complete genome	14 crisprs	WYL,cas3,csa3,DEDDh,DinG	1	5	2	0

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP045920_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045920_1

492323-492402

Orphan

Consensus_repeat	Method
TCGGTGCCCGCGTCGGCCCCGTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045920_1

>merge|NZ_CP045920|1|492323-492402|CRISPRCasFinder
TCGGTGCCCGCGTCGGCCCCGTCGCTGTCGGAGGCGCCGCCGATTTCGGAGGTTCCTTCGGTGCCCGAGTCGGCCCCGTC

>NZ_CP045920|1|1|492323-492402|CRISPRCasFinder
TCGGTGCCCGCGTCGGCCCCGTC	GCTGTCGGAGGCGCCGCCGATTTCGGAGGTTCCT
TCGGTGCCCGAGTCGGCCCCGTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045920.1\|WP_152817232.1\|496021_496471_-\|nitroreductase-family-deazaflavin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|281995
NZ_CP045920.1\|WP_153877198.1\|475775_477008_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045920.1\|WP_153879124.1\|502322_503114_-\|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|238870
NZ_CP045920.1\|WP_153877207.1\|496565_497255_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045920.1\|WP_153877200.1\|481371_482181_-\|trehalose-phosphatase	unknown	unknown	gnl\|CDD\|319767
NZ_CP045920.1\|WP_152817235.1\|499838_501842_+\|prolyl-oligopeptidase-family-serine-peptidase	unknown	unknown	gnl\|CDD\|224423
NZ_CP045920.1\|WP_153877211.1\|507957_508632_-\|uracil-DNA-glycosylase	unknown	unknown	gnl\|CDD\|235376
NZ_CP045920.1\|WP_153877210.1\|505875_507897_+\|trypsin-like-serine-protease	unknown	unknown	gnl\|CDD\|365866
NZ_CP045920.1\|WP_152817236.1\|501838_502315_+\|carboxymuconolactone-decarboxylase-family-protein	unknown	unknown	gnl\|CDD\|225039
NZ_CP045920.1\|WP_152817223.1\|478382_479507_-\|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC	unknown	unknown	gnl\|CDD\|236947
NZ_CP045920.1\|WP_153877201.1\|482173_483655_-\|trehalose-6-phosphate-synthase	unknown	unknown	gnl\|CDD\|340820
NZ_CP045920.1\|WP_153877202.1\|483748_485407_+\|protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP045920.1\|WP_152817234.1\|497383_499729_+\|bifunctional-metallophosphatase/5'-nucleotidase	unknown	unknown	gnl\|CDD\|236505
NZ_CP045920.1\|WP_152817222.1\|477038_478292_-\|DUF4032-domain-containing-protein	unknown	unknown	gnl\|CDD\|379077
NZ_CP045920.1\|WP_153877205.1\|490012_491392_+\|IS1380-family-transposase	unknown	unknown	gnl\|CDD\|379340
NZ_CP045920.1\|WP_153877208.1\|503155_505108_-\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|173850
NZ_CP045920.1\|WP_153877203.1\|485457_486237_+\|thioredoxin-domain-containing-protein	unknown	unknown	gnl\|CDD\|372611
NZ_CP045920.1\|WP_153877209.1\|505180_505603_-\|META-domain-containing-protein	unknown	unknown	gnl\|CDD\|377111
NZ_CP045920.1\|WP_153877199.1\|479640_481317_-\|DHA2-family-efflux-MFS-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|129794
NZ_CP045920.1\|WP_153877204.1\|486612_490131_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|271234

Protein	Function_ID	Function_description	E-value
NZ_CP045920.1\|WP_152817232.1\|496021_496471_-\|nitroreductase-family-deazaflavin-dependent-oxidoreductase	gnl\|CDD\|281995	pfam04075, F420H2_quin_red, F420H(2)-dependent quinone reductase. This family of proteins is found in the genera Mycobacterium and Streptomyces. Member protein Rv3547 has been characterized as a deazaflavin-dependent nitroreductase. Rv1558 is an F420H(2)-dependent quinone reductase involved in oxidative stress protection.	1.96573e-54
NZ_CP045920.1\|WP_152817236.1\|501838_502315_+\|carboxymuconolactone-decarboxylase-family-protein	gnl\|CDD\|225039	COG2128, COG2128, Uncharacterized conserved protein [Function unknown].	3.38459e-14
NZ_CP045920.1\|WP_153879124.1\|502322_503114_-\|SGNH/GDSL-hydrolase-family-protein	gnl\|CDD\|238870	cd01832, SGNH_hydrolase_like_1, Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad from other serine hydrolases, but may lack the carboxlic acid. Myxobacterial members of this subfamily have been reported to be involved in adventurous gliding motility.	6.06414e-55
NZ_CP045920.1\|WP_153877200.1\|481371_482181_-\|trehalose-phosphatase	gnl\|CDD\|319767	cd01627, HAD_TPP, trehalose-phosphate phosphatase similar to Escherichia coli trehalose-6-phosphate phosphatase OtsB and Saccharomyces cerevisiae trehalose-phosphatase TPS2. Trehalose biosynthesis in bacteria is known through three pathways - OtsAB, TreYZ and TreS. The OtsAB pathway, also known as the trehalose 6-phosphate synthase (TSP)/ Trehalose-6-phosphate phosphatase (TPP) pathway, is the most common route known to be involved in the stress response of Escherichia coli. It involves converting glucose-6-phosphate and UDP-glucose to form trehalose-6-phosphate (T6P), catalyzed by TPS, the product of the otsA gene, this step is followed by the dephosphorylation of T6P to yield trehalose and inorganic phosphate, catalyzed by a specific TPP, the product of otsB gene. This OtsAB (or TSP/TPP) pathway, is also the most common route known to be involved in the stress response of yeast In Saccharomyces cerevisiae, the corresponding enzymes, TPS1p and TPS2p, form a multimeric synthase complex together with additional regulatory subunits encoded by Tsl1 and Tps3. Trehalose is a common disaccharide accumulated by organisms as a reservation of carbohydrate and in response to unfavorable growth conditions. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.19059e-41
NZ_CP045920.1\|WP_152817235.1\|499838_501842_+\|prolyl-oligopeptidase-family-serine-peptidase	gnl\|CDD\|224423	COG1506, DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism].	7.03107e-79
NZ_CP045920.1\|WP_153877211.1\|507957_508632_-\|uracil-DNA-glycosylase	gnl\|CDD\|235376	PRK05254, PRK05254, uracil-DNA glycosylase; Provisional.	1.39374e-115
NZ_CP045920.1\|WP_153877210.1\|505875_507897_+\|trypsin-like-serine-protease	gnl\|CDD\|365866	pfam00089, Trypsin, Trypsin.	0.000132036
NZ_CP045920.1\|WP_152817223.1\|478382_479507_-\|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC	gnl\|CDD\|236947	PRK11650, ugpC, sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC.	0
NZ_CP045920.1\|WP_153877201.1\|482173_483655_-\|trehalose-6-phosphate-synthase	gnl\|CDD\|340820	cd03788, GT20_TPS, trehalose-6-phosphate synthase. Trehalose-6-Phosphate Synthase (TPS, EC 2.4.1.15) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain.	0
NZ_CP045920.1\|WP_153877202.1\|483748_485407_+\|protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	7.22318e-62
NZ_CP045920.1\|WP_152817234.1\|497383_499729_+\|bifunctional-metallophosphatase/5'-nucleotidase	gnl\|CDD\|236505	PRK09419, PRK09419, multifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase/5'-nucleotidase.	2.69908e-78
NZ_CP045920.1\|WP_152817222.1\|477038_478292_-\|DUF4032-domain-containing-protein	gnl\|CDD\|379077	pfam13224, DUF4032, Domain of unknown function (DUF4032). This presumed domain is functionally uncharacterized. This domain family is found in bacteria, and is approximately 170 amino acids in length. The family is found in association with pfam06293.	2.94029e-93
NZ_CP045920.1\|WP_153877205.1\|490012_491392_+\|IS1380-family-transposase	gnl\|CDD\|379340	pfam13701, DDE_Tnp_1_4, Transposase DDE domain group 1. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.	5.16378e-19
NZ_CP045920.1\|WP_153877208.1\|503155_505108_-\|acyl-CoA-dehydrogenase	gnl\|CDD\|173850	cd01161, VLCAD, Very long chain acyl-CoA dehydrogenase. VLCAD is an acyl-CoA dehydrogenase (ACAD), which is found in the mitochondria of eukaryotes and in some bacteria. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. VLCAD acts as a homodimer.	2.99816e-93
NZ_CP045920.1\|WP_153877203.1\|485457_486237_+\|thioredoxin-domain-containing-protein	gnl\|CDD\|372611	pfam13462, Thioredoxin_4, Thioredoxin.	3.19902e-14
NZ_CP045920.1\|WP_153877209.1\|505180_505603_-\|META-domain-containing-protein	gnl\|CDD\|377111	pfam03724, META, META domain. Small domain family found in proteins of of unknown function. Some are secreted and implicated in motility in bacteria. Also occurs in Leishmania spp. as an essential gene. Over-expression in L.amazonensis increases virulence. A pair of cysteine residues show correlated conservation, suggesting that they form a disulphide bond.	3.81587e-12
NZ_CP045920.1\|WP_153877199.1\|479640_481317_-\|DHA2-family-efflux-MFS-transporter-permease-subunit	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.18822e-65
NZ_CP045920.1\|WP_153877204.1\|486612_490131_+\|hypothetical-protein	gnl\|CDD\|271234	cd15482, Sialidase_non-viral, Non-viral sialidases. Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates, they play vital roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold with the non-viral sialidases containing 2-5 Asp-box motifs (most commonly Ser/Thr-X-Asp-[X]-Gly-X-Thr- Trp/Phe). This CD includes eubacterial and eukaryotic sialidases.	1.26837e-89

>NZ_CP045920.1|WP_153877205.1|490012_491392_+|IS1380-family-transposase
MQLSHVSSVRFDDPNLVGVAGLVPVMALAERAGLSALVGEHLSLSGAGSANPGAKVLALVAGMTAGADSIDDMDLLRHGGMGKLFQDARAPSTLGTFLRAFTFGHVRQLDAIASRFLTRLAGQAPVLAGAGQIAYVDIDDTIKETYGYAKQGAGYGYNKVKGLNALIATVATPVAAPVIVGTRLRRGPANSARGAGKFVADSLAAARTAGAGGVVILRADSAYYSREVAAAAGRAGAHFSLTARMNPAITAAITSIDAQAWTPIRYPNAIWDEDEGRLISDAQVAEIPFTAFTSRPKAEHISARLIVRRVKRLNPAATRAGQDELFATYRYHAVFTDSPLSMLEAEKAHRAHAIIEGVHADLRASALAHAPSGKFTANAAWLVLAAIAFNLTRAAGTLASLFHARATTATIRDHLIRVPARIASSARRLIMHLPRNWAHQGPWEALYVAACGPPPAPAT
>NZ_CP045920.1|WP_153877204.1|486612_490131_+|hypothetical-protein
MTAIAMGPRRRGRAIGLLGLLVAAAASLGLLGLAPVAAEAATSDDGSISAEIEFVDPAEDGEYAVGDVLAFTYVVVNLLDEDRSLSLVESNLDGDEGCKWFKAAPGAEQRCVGRATHTVTAADLAAGAFTPTATWGIHSGIDYVGIASEVEVVGEPVDLIGPGIRAEVVATNAQADHDYEVGDVLEFAYVVTNLLDEARSTQLLESNLDGDAGCKWSSHPAGTTYECGTPRHTVTAADLEAGSFVPTATWAIHTGTGYPGAQESIEIVGDPVGLVDHTEAGNGGLDFDASWEGEPLYTSTQLATNGVGGFPNYRIVALAVTNSGDLLASYDGRPTGADSPGPNSILQRRSTDGGQTWEEQTVIHAGKVSRPIHGFSDPSYIVDRITGEVFNFHVYSQDQGFFGSHAGTDPSDRNVAHVEVSRSTDGGRTWTHEIITDQITPDPSWTSRFATSGQGIQLKYGEHAGRLIQQFPVMVAGVIKAVSVYSDDHGDTWQAGTPVGVSMDENKTVELSDGRVMLNSRDSARSGYRKVAYSTDGGVTYGEVTLDRELPDPTNNASIIRAFPNAAEGSDEARILLFSNSASTTSRTNGTIRMSCDDGQTWPISKTFEPGGMAYSTLATQPDGSIGLLYEPGGGGGGIAYANFNLAWLGGICAGVTADEASVDPGSSVDVQLTVTNQTSAALTGAAIALDLPAGWTASEAVVPEIAPGGSVRVPVTIAVPGGEVPQTVRIPLTLTTPRGSSSGSLSVRANAPAGQPITVVGTHTNPKELDTYEVGDRLEFTFAVENISGGPIAVVPDGTLEGFDPDDGAPNCRYRALPTDGGYECTTAFHVVTQADLDAGEFAPVTSWDAREGGESGPSIGSIALDSPVVILTSGSTGDSDGSDADADGSDGTDAGSDGSDAGSDGSVGGSDGSDGSDAGADGSGAGSDGGSDGSDAGTDGSGAGSDSGSDGSDGADVGADGSDAGTDGSDAGSDSGSDGSDGGSDGADVDADGSGAGSDGGSDGSDAGADGSGAGSDGGSDGSDGADVGADGSDAGADGSGAGADSPDGSDAGSGDEGADRLPSTGIAATAAGLLALTLIGLGMALRGRRLNLDPPCWFESGWRGSMRMPSWPGIMRVVNARSPKKEGHLVDATISCLLGTVRRSEPGRRGGSCPGDGAGRAGRAVGAGR
>NZ_CP045920.1|WP_153877203.1|485457_486237_+|thioredoxin-domain-containing-protein
MSANTKRREDARKQAEKIAAKQASSDNRTRNILILIIAAVIALLVVAGIVLYKQSQRTPLSDFEGTAPAAADTHGGIAFSDQGVGVVGSGPVVQVYVDFLCPICGDFEEVNGADLVELVEAGTATVVYHPVNFLDRYSQGTAYSTRAANAFVTVAEDAPDQALDFMTALFEQQPAENTTGLTDEEIAGIAVDAGVPQEVADTFGDLTYGDWVDAASQQATRDGVTGTPSVVINGTPLDTKKYNWTQPGVLRDHIEELAG
>NZ_CP045920.1|WP_153877202.1|483748_485407_+|protein-kinase
MSSDEDPGEPLGQIGGYELRRVLGTGGMGTVYEAADGAGLTVALKALHPAFAADPESRERLRREVATLHQVRGAQVAQVIDAEVDSTEAFIVTELIHGQPLDQSVHTHGPLEIRELADLAAGLATALQQIHGVHVVHRDLKPSNVMLTEAGPVLIDFGISQLVDDARITRTGLVTGTPGYVDPVVLGGAAPDQLGDWWGWAALLVFAATGREPFGTGPATLARATEGRVDAEGLPRPVAEVLTVALNPDPRYRLPPADVVELLGEIARGRHVSVPPAAVAGARDGHGSQPPYGSMGTAGPVGTAGPAGTAGPAGAPPPSYPPGGPPPAQRVARDSLVESWPRFHSTVAEPVRAYPGPEPYYAPDLAERGLRPAPSRPVMTTLAWLVLVAFAVRAAGSATIAFVAVLAGAGAWGWGERRLRDRRMRFGRRRRDGALVWLAAPVHLVSGVVTALPGLIAGAVVALGAWLVLGRFIAAGLAAGLAVALLAFMAWFVPSSGAARAGVRRVWAVMMPNRGAAAGATVVAVVLLGVVGLWALGQVDSASWDPFPMPTP
>NZ_CP045920.1|WP_153877201.1|482173_483655_-|trehalose-6-phosphate-synthase
MHDSQEGPAQEFVVVANRLPVDVSVDEDGTISWIRAPGGLVTALAPMMRSGGGAWVGWSGSADLELDPFTDDGIAMTPVPLSAAEIEEFYEGFSNATLWPLYHDVIVDPEYHREWWSVYRTVNERFAAAAAAVAAPGATVWVQDYQLQLVPALLRSARPDLHIGFFLHIPFPPMELFGQLPWRHQVLEGLLGSDLIGFQRSGDAANFLRSVRRFTAHPVRGQNVSITTPFANPGRTIRAGAFPISLDSKAFNQLANRPETIERARQIRRDLGDPQVLLLGVDRLDYTKGIRHRIKAFGEMLAEGAIGNGEAVLVQVASPSREQVAEYVQLRSEVEEMVGRINGDHAEIGRPVIHYLHHSYPAEEMAAMFRAADVVLVTALRDGMNLVAKEYVAARSDLDGVLVLSEFAGAADELTSALQVNPHDIEGMKTTILSAMRMPREQRRRRMRALRRRVLTNDVAHWARSFLTALAHQGGLNQAPLPGSRTDVEARDD
>NZ_CP045920.1|WP_153877200.1|481371_482181_-|trehalose-phosphatase
MTDGPLAPGLLRALADFARRPRVLVALDFDGCLAPLVEDPARARPTERAAAALAEFGRMDDVHLALVSGRPAADLVTLADPPAGTRLIGSHGAERARLEGGGVAHEPFTLTDAQRELLERVSAAAEEIAAGHPGAWVEHKPAAAVLHTRPLAPGPAAAATAAALAGPAGLPGVHPIRGNQVVELAVVPSTKGGALVALRAELAGDGDPLPVLYAGDDVTDETALATLGDGDVGIKVGAAESVAPYRVAGPEELARALAVLARERGGRPA
>NZ_CP045920.1|WP_153877199.1|479640_481317_-|DHA2-family-efflux-MFS-transporter-permease-subunit
MTSLRLRGRDHPVPALAGRRRWLALTILAAGVAMIVIDGTIVNVSLPVLIRDLDLDLTDAEWVNSIYTLIFASLLLTTGTIGDRYGRRRVFAAGVVVFVAGSLWAGFATGGSSLIGARALQGLGGAAILPSTLSVVNALFRGRDRAIAFAVWGSVIAGTAAVGPLLGGWLTTDVSWRWIFWVNLPVGAAILAGILLVIPETRDPNPGRGFDVTGVVLSAITFGGLVLGLIEGNSYGWWVPRGDFHLAGLSWSLPLSMPATALLVAAASLVAFIAWQRHRRAAGRAAVVDLALFRHRSFGLGNAAALLVALGEFGMLFVLPLYLQNALGLSAMGAGWVLAGLGAGAFVAGGIAGPLARRITPAGVASVGLAIETVGLVLVALVVGPATSPALIAVLLAGYGIGLGFASAQLTGTILSEIPPARSGQGSAVQSTTRQLGSALGVAVLASILSAFATSRAAGSLAGIDGVGAAQAARLESSLGPSAGGVLGSLDRLGLPAAAQDQVHGALTAAFSAGVQSTMLVAAIALAVGFAATLFLPRIHGGEAGDGTGGEHTSDPRR
>NZ_CP045920.1|WP_152817223.1|478382_479507_-|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC
MASVTFDAASRIYPGTERPAVDALDLEVSDGEFLVLVGPSGCGKSTSLRMLAGLEDVNAGRILIGDRDVTDVQPKDRDIAMVFQNYALYPHMSVADNMGFALKIAGINKAEIRQRVEEAAKILDLSEYLDRKPKALSGGQRQRVAMGRAIVRQPQVFLMDEPLSNLDAKLRVQTRTQIASLQRRLGVTTVYVTHDQTEALTMGDRIAVLNFGVLQQVGTPRDMYDRPANTFVAGFIGSPAMNLGKFKVAEGKAHLGDAHVPLPRATVDALTPEDEGKIILGFRPESLDVTSEGTEGAFPVRVNLVEELGSDAFLYGELDSKDAAEHITSGAGDAQMIVRVNPRTPPMKGDRVWVKIREGESHMFSAGTGERLPN
>NZ_CP045920.1|WP_152817222.1|477038_478292_-|DUF4032-domain-containing-protein
MPARLQITVAQPDPALFELPWEIPLAEWPEDILAALPRGISRHVVRFVRIPGGVIAIKEIGETVAYREYELLRDLNRLEVPSVTPVGVIGGRTAPDGSPLDSVLITRHLRFSLPYRALFSRHLTPNMATRLIDALAVLLVRLHVTGFYWGDVSLSNTLFRRDAGEFAAYLVDAETGDLHDTLTVGQREYDLEIARVNIIGELMDLDAGGVLPEGTDTVAIGDRLAERYQELWRELTAPESFSGSERWRVTARIRRLNMLGYDVGELTMTADLDGTTVSIQPKVVDAGHHHRRLMRLTGLDVQENQARRLLNDMDTFRAAKDRLGDDEEYVAHDWLTDVFEPVQRMIPRDLRGKLEPAEIFHEILEHRWFMAENAGHEVSLSDATRSYVDSVLRHRPDEEAMLELDTATLRAITDTEH
>NZ_CP045920.1|WP_153877198.1|475775_477008_+|hypothetical-protein
MNWRRSTGIVISKTGQAVRAAGFLDGAQVLARIESDPEAPDSVLVTVAVDEADRVAILSEDGRRIVPGPAVADLAQAIADDVHGEVGFAEAAGRAEDSEQGAAGPDPFDQHLDVDAAYAPDRAVIFARTGAAGVIDLATAVDQRVFTREHLDGQLVFVADGPALTAVEWPGALRPALVIEQGAAFPALTAVTVDGSAHVHTWDVQVTEVPDVSGDALGGVRAFLDTVIGTGALVGRLMRLFPAAEPLGVRTALDGVDAGPARLLAALGLPADAAAFLVHDRAAGELEQVTPVDPDTLVESLRRAMSGASVTMTETAEAMRQRAEAMRLRAETVFDAAETFTEEVVLPARQSWLTPSLAVAEAVLGALAIRRARRGGALGVISGVLGAVLLTDATVNLAIAASPLLRRGRD
>NZ_CP045920.1|WP_152817232.1|496021_496471_-|nitroreductase-family-deazaflavin-dependent-oxidoreductase
MPLEGTYEPSSDPAAAWAREQAELYEGSGGTKGTTLHGRPVVLVTSIGARSGRLRKTPVMRVEHEGEYAVIASKGGAPNHPAWYHNLVAHPQVELQDGADRHDYIAREVSDPERARWWARAVDAFPPYASYQEKTDRLIPVFVLTRMSD
>NZ_CP045920.1|WP_153877207.1|496565_497255_-|hypothetical-protein
MISTRRSPSRRVVRGSVAAGMGMLLLALGACTAPSGPSGPSGPSGPDAGAATTGGVDEPSATTEPVTEPVEPTTDPTTLAPAGAECLIGEWQVSQDTLQGYYDSLEVPAGFAIEGGTGLTFTADRYTYTPDFTLTMDIAGQRASGITTGSVSGSYTAEDGVISTSGDENNLELTIEVGGQSIDGGAAAGDLLDSVPIASAPFECTPEGPILMFGAGSAGRVPVQLEPAG
>NZ_CP045920.1|WP_152817234.1|497383_499729_+|bifunctional-metallophosphatase/5'-nucleotidase
MRLGTMTAGRASWRGPAAALGVAALALAGVATAVPAAADIDGDTLTVDLVGVNDFHGRIDEGLKVSTDADGTVTIADENTGAAARLAAAVEDVRADNADTVFVGAGDLFGASTFTSMIGDDIPTTDVFNAMGLDVSSVGNHEFDQGIATLKERIDGTGDFAGHALDWPYLGANVYDESTGDPALQEYDVIETANGASIAFIGVVTQETPSLVTPAGIAGLDFGDPADAVDRVIEENTEVADADAIVVLIHDGGANAAAVTDTATHFGRFVQDMADRGDIAGIFSGHTHVMYEVAVDGMPVIQTGSFGANLGRITLSFAVTGSGDTRELSLSGAASDMIPLSWKDDEGATVYYPVPEGNDVVDAVKDVVRTAVEAAEELGGQVIGHVSDDLNRAVQSEVDAETGEPIENRGGESTIGNLIADAQIWAIDEQAATDDLPVVAFMNPGGIRTDIKYGTDGTVTYKQAATVQPFANTLNTFDLTGAQIKQVLEEQWQPEGASRPFLKLGLSGMWYFYDPAAPTGEHITYVEIGGEQLDPDATYRVVANNFLASGGDNFTTLGEGADYADSGIVDLAAFVDYFKAAEAAGEVVTPDYDQRAIGVHWNTSQEDTYRVGEEISLDLSSMLFSTNEPKPEVLGLALVNPDTEETVDLGTTPLDPSIVDTTDEVGRAQVRLTVPEIDGLGEDPQAWRLQVTDAVNGYSVWFGVALTAAAASPTPTDTASPTPTPTTSATPAPTPSVTVPGGSMPDTGADVDLAAIVGVLLLLNGAAAVAVARRRRSSARD
>NZ_CP045920.1|WP_152817235.1|499838_501842_+|prolyl-oligopeptidase-family-serine-peptidase
MTPDQLALIRTLGTPAPHPDGGWAAVAVTGADLAADAYRSRLWRVDLATGDLTPLTHGELDTAPVCSPDGRRLAFLRAGADGLPQVAVMPTGGGEPLVLTDHECGVSGPLRFSADSTRLAYAARVPEPGRYGTDAAVDAHAEPPRHITHLDYRAEGTGFHLDRPERVFTLTLPGPLDPQADPQADPAPLDDVARPARAGAPTRPVAVTSGAGAFRAPIWFGEDLLALREVRGAHHCELVRIRPDGTASVVDTGAWIVGGLVRDLTHERRVWLLLADYGPDRTDFIGKRAALASADLVGTELIDLRVHTDPQAGGLVADGFCAVQGGVVIARERRGSVELLRYDGELTSMLSGPVTVTSAAGIGTSAGALAVAAGIGSAGDLWHIGADGEARQVTDLSARLRREAGVFTPAELEVSAADGYPVHGWVTQPAGEGPHPVLLLIHGGPHAAYSPTYFDEVQAYTAAGYAVVFCNPRGSASYGQAHGRATIGGWGRLDAQDVLAFLDGALAAHPRLDPGRVGVMGGSYGGYLTAWLTTIDHRWHGAIVERGFLDPVSFEGSSDIGWFFGLQYLGSDPELVAAQSPMAAIGRVRTPTLVIHSEHDWRCPLEQGQRWFVGLKRRGVPAEFLLFPGEGHELSRSGRPAHRRARFDHILAWWQRHLPVTEGAARS
>NZ_CP045920.1|WP_152817236.1|501838_502315_+|carboxymuconolactone-decarboxylase-family-protein
MSIRRVNPAHAAEAFAASERLGEEAKTAALAAGLDLRAIELIRLRCSQLNGCAMCLKAHTAAALAAGETVERIGVLTAWRETRYFSDVERACLELAEAVTLVAQRHLDDDGYTALAAVLAPEQISAATWVAIAINDSNRIWIHADRPVHPPREQPSGS
>NZ_CP045920.1|WP_153879124.1|502322_503114_-|SGNH/GDSL-hydrolase-family-protein
MGDSFTEGLWDTAPEDPEVQYGWADRLAFTLSGYRHEAGQEPLEYANLAIRGRLLESILTDQLPRALEQRPDLISIAGGGNDVLHLGCSPDRLAALLDGAVARVRATGTRVLLATGMDTRGLALLGALRHKIAIYNADLWSIAHRHGAAVIDLWGMRSLRDRRMWAEDRIHLSPEGHRRVAQAGLVALGLPPGDPGWELPRGPGETVASLAQLRDDAAWLRRDVYPWATRRLRRASTGDARRAKYPDLRLVEAAVDAPGRAGR
>NZ_CP045920.1|WP_153877208.1|503155_505108_-|acyl-CoA-dehydrogenase
MSNASRVTERDARRVAEQSRQTEWEHDSFARQLYLGDFRPELVWESERLDPEVRVRGDAYLARLERHLRENVDGSVIEAEDRIGDDVLAGLIDLGVFGLKIPPEYGGIGLGQVHYNRALMLLGSAHPSIGALASAHQSIGVPEPVEQFGSEELKHRFLPRCAAGAISAFLLTEPDVGSDPARLQAAAVPTPEGDYLLDGVKLWTTNGVLAELLVVLARVPEHEGGRGGITAFVVEADSEGITVEHRNSFMGLRGLENGVTRFDGVRVPAENVVGREGQGLKIALTTLNTGRLSIPAMCVAGSKWALGIAREWSNARVQWGRPIGRHPAIGHKLAFMAATTYAQEAVVEVAGAMADSGGVDIRIEAALAKLWCSEMAWRVADDLVQIRGGRGYETAASLRARGERAVATEQLLRDLRINRIFEGSSEIMHLLIAREAVDTHLSVAGPLIDPEAGGAEKSAALAAAATFYAGWLPRLAAGPGTLPGSFREYGPAASHLRYVERASRRLARSTFYGMARWQGRLEHKQGFLARIVDIGAELFAMTAVWAHADREGTGADGTPALTADSPAVLADAFCRQSRRRIDSLFRALWINTDAHDEDVARRVLDGEFTWIEAGVIDPSAGTGPWIAEDHRGPSSEPNVRRRYRTSTVVR
>NZ_CP045920.1|WP_153877209.1|505180_505603_-|META-domain-containing-protein
MLFLRRAAIVTTAALTLGGVVFALWLGPLSGGGSGAEGDGATPAPGVHVAGRWGGDGDRAPHLIFGAHGEVSGNDGCNGLSGSYTATGDGEVDFHDVLGTLKACPGVDTWLHRLASAVVDGDELAVFDAAGEEIGRLPRA
>NZ_CP045920.1|WP_153877210.1|505875_507897_+|trypsin-like-serine-protease
MRRTRPTLTGAAIGGSLALAFGAGMVALPAAADSDVQLPSDWQAVAAELLDTGVDPRPSAQSADSSNVAAVGVDADGGLVIAVDGEGIDAGIDEARIAAYEDRATIVQVEGGFSALAAPGSVVGGAGIYTDTADNQASVCSVGFSSWNSTGEPAVVTAGHCTDDGALVDVGLSVPENDAAGGGILPGPDLGVYGFSQFGGPGNTAGSEIDPGTDIAVIDEINTDLTLSPEITDWTDTDDLAASTTVITGVGAVDPNGAAIERSGRTTGHSSTSAANVSMIAGVAEVDGRYVLGFLVDDIAVDQGDSGGPVYQGETAIGIVSGGNPTGNQLWAADLQDALAHTDGYTIQLHIDAPAVTAPDAGGDIDAGDAITGTAPAGTTLVVQPVGGDEFTVDVDSDGTWSFDAPQELGDYAFTLQAENGYNASETVEHDVNVTLPAPAITAPADGDRVTEAISSVSGTGYDGATVHVTIDGEELTAEVAGGAWSVETDLGYGPHEVGAYQVFEEQQSATVTAAVTVAPAAPEITVPADGGFFAETELTDVLDVEGTGIDGATVTLLVDGEQAGTAVVTGGAWSIAVDRDFAPGDYTLAAAQTIDGTDSDETSIMFSVMSVIDEDPTVDPTDDPTAGPTDGPTDGPDRLPDTGASAATLPFLGAAAALVMLGVAGVIRRQRA
>NZ_CP045920.1|WP_153877211.1|507957_508632_-|uracil-DNA-glycosylase
MRTPLEQAIDPGWARALAPVEPVLRELGDFLRAEDAAGPGFLPAAEHVLAAFTRPPAQVRVLLVGQDPYPTPGHAMGLSFSVQPHVRPLPRSLANVFTELVDDLGVPRPTTGDLRPWADRGVLLLNRSLTVSPGRPASHRGRGWEQVTGAAIDALVARGGPLVAVLWGRDARALRPRLGSVPVVESAHPSPLSATRGFFGSRPFSRVNSLLTTLGADPIDWRLP

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP045920_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045920_2

545038-545420

Orphan

Consensus_repeat	Method
GANGGTGGNTCCGACACCGGGGCCGGTTCGGANGG	CRT

6 spacers

The CRISPR arrays of NZ_CP045920_2

>merge|NZ_CP045920|2|545038-545420|CRT
GACGGTGGGTCCGACAGTGGGGCCGGTTCGGATGGTGGCTCCGATACCGGGGCCGGTTCGGATGGTGGCTCCGACACCGGGGCCGCTTCGGACGGAGCCGTCGATGCGGGAACGGATGGTGGCTCCGACACCGGGGCCGGTTCGGACGGTGCCCTTGACGGTGGGGCCGATGTCGATGGTGGCTCCGATACCGGGGCCGGATCGGATGGTGGCTCCGACACCGGGGCCGGAACGGACGGTGGCTCCGACACCGGAGCGGGTTCGGACGGAGCCGTCGATGCGGGAACGGACGGCGGTGCCGACACCGGGGCCGGTGCGGACGGAGCGCTCGGCGGCGGAGCCGATGTCGATGGTGGATCCGAGAGTGGGGCCGGTGTGGAGGG

>NZ_CP045920|2|1|545038-545420|CRT
GACGGTGGGTCCGACAGTGGGGCCGGTTCGGATGG	TGGCTCCGATACCGGGGCCGGTTCG
GATGGTGGCTCCGACACCGGGGCCGCTTCGGACGG	AGCCGTCGATGCGGGAACG
GATGGTGGCTCCGACACCGGGGCCGGTTCGGACGG	TGCCCTTGACGGTGGGGCCGATGTC
GATGGTGGCTCCGATACCGGGGCCGGATCGGATGG	TGGCTCCGACACCGGGGCCGGAACG
GACGGTGGCTCCGACACCGGAGCGGGTTCGGACGG	AGCCGTCGATGCGGGAACG
GACGGCGGTGCCGACACCGGGGCCGGTGCGGACGG	AGCGCTCGGCGGCGGAGCCGATGTC
GATGGTGGATCCGAGAGTGGGGCCGGTGTGGAGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045920.1\|WP_153877226.1\|526138_527377_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340874
NZ_CP045920.1\|WP_152817269.1\|530760_531252_+\|MogA/MoaB-family-molybdenum-cofactor-biosynthesis-protein	unknown	unknown	gnl\|CDD\|238451
NZ_CP045920.1\|WP_153877230.1\|532781_533864_+\|DeoR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380491
NZ_CP045920.1\|WP_153877228.1\|529302_530637_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226789
NZ_CP045920.1\|WP_153879126.1\|545751_546519_+\|inositol-monophosphatase	unknown	unknown	gnl\|CDD\|223559
NZ_CP045920.1\|WP_153877238.1\|548874_549735_-\|amidohydrolase-family-protein	unknown	unknown	gnl\|CDD\|226145
NZ_CP045920.1\|WP_153877236.1\|547952_548375_-\|QacE-family-quaternary-ammonium-compound-efflux-SMR-transporter	unknown	unknown	gnl\|CDD\|224987
NZ_CP045920.1\|WP_153877240.1\|550820_552140_-\|fuconate-dehydratase	unknown	unknown	gnl\|CDD\|239440
NZ_CP045920.1\|WP_153877237.1\|548423_548873_-\|transport-protein-RbsD/FucU	unknown	unknown	gnl\|CDD\|226632
NZ_CP045920.1\|WP_153877239.1\|549731_550700_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381378
NZ_CP045920.1\|WP_153877234.1\|546854_547652_+\|FCD-domain-containing-protein	unknown	unknown	gnl\|CDD\|225097
NZ_CP045920.1\|WP_153877231.1\|533935_537049_+\|sugar-isomerase	unknown	unknown	gnl\|CDD\|238517
NZ_CP045920.1\|WP_153877232.1\|537282_541419_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379625
NZ_CP045920.1\|WP_153877241.1\|552318_553191_+\|FAA-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
NZ_CP045920.1\|WP_152817265.1\|528493_528784_-\|WXG100-family-type-VII-secretion-target	unknown	unknown	gnl\|CDD\|274862
NZ_CP045920.1\|WP_153877235.1\|547629_547956_-\|QacE-family-quaternary-ammonium-compound-efflux-SMR-transporter	unknown	unknown	gnl\|CDD\|224987
NZ_CP045920.1\|WP_152817271.1\|531651_532689_+\|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl\|CDD\|234672
NZ_CP045920.1\|WP_152817281.1\|546515_546758_-\|MoaD/ThiS-family-protein	unknown	unknown	gnl\|CDD\|340452
NZ_CP045920.1\|WP_153877229.1\|531244_531670_+\|molybdenum-cofactor-biosynthesis-protein-MoaE	unknown	unknown	gnl\|CDD\|238385
NZ_CP045920.1\|WP_153877227.1\|527415_528351_-\|DUF4031-domain-containing-protein	unknown	unknown	gnl\|CDD\|226789

Protein	Function_ID	Function_description	E-value
NZ_CP045920.1\|WP_153877226.1\|526138_527377_+\|MFS-transporter	gnl\|CDD\|340874	cd17316, MFS_SV2_like, Metazoan Synaptic vesicle glycoprotein 2 (SV2) and related small molecule transporters of the Major Facilitator Superfamily. This family is composed of metazoan synaptic vesicle glycoprotein 2 (SV2) and related small molecule transporters including those that transport inorganic phosphate (Pht), aromatic compounds (PcaK and related proteins), proline/betaine (ProP), alpha-ketoglutarate (KgtP), citrate (CitA), shikimate (ShiA), and cis,cis-muconate (MucK), among others. SV2 is a transporter-like protein that serves as the receptor for botulinum neurotoxin A (BoNT/A), one of seven neurotoxins produced by the bacterium Clostridium botulinum. BoNT/A blocks neurotransmitter release by cleaving synaptosome-associated protein of 25 kD (SNAP-25) within presynaptic nerve terminals. Also included in this family is synaptic vesicle 2 (SV2)-related protein (SVOP) and similar proteins. SVOP is a transporter-like nucleotide binding protein that localizes to neurotransmitter-containing vesicles. The SV2-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	9.12953e-20
NZ_CP045920.1\|WP_152817269.1\|530760_531252_+\|MogA/MoaB-family-molybdenum-cofactor-biosynthesis-protein	gnl\|CDD\|238451	cd00886, MogA_MoaB, MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea, and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MogA, together with MoeA, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes. In contrast, MoaB shows high similarity to MogA, but little is known about its physiological role. All well studied members of this family form highly stable trimers.	2.11821e-54
NZ_CP045920.1\|WP_153877230.1\|532781_533864_+\|DeoR-family-transcriptional-regulator	gnl\|CDD\|380491	cd06267, PBP1_LacI_sugar_binding-like, ligand binding domain of the LacI transcriptional regulator family belonging to the type 1 periplasmic-binding fold protein superfamily. Ligand binding domain of the LacI transcriptional regulator family belonging to the type 1 periplasmic-binding fold protein superfamily. In most cases, ligands are monosaccharide including lactose, ribose, fructose, xylose, arabinose, galactose/glucose, and other sugars. The LacI family of proteins consists of transcriptional regulators related to the lac repressor. In this case, the domain sugar binding changes the DNA binding activity of the repressor domain.	5.8433e-48
NZ_CP045920.1\|WP_153877228.1\|529302_530637_-\|hypothetical-protein	gnl\|CDD\|226789	COG4339, COG4339, Uncharacterized protein conserved in bacteria [Function unknown].	4.04762e-30
NZ_CP045920.1\|WP_153879126.1\|545751_546519_+\|inositol-monophosphatase	gnl\|CDD\|223559	COG0483, SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism].	3.23483e-50
NZ_CP045920.1\|WP_153877238.1\|548874_549735_-\|amidohydrolase-family-protein	gnl\|CDD\|226145	COG3618, COG3618, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only].	1.67581e-35
NZ_CP045920.1\|WP_153877236.1\|547952_548375_-\|QacE-family-quaternary-ammonium-compound-efflux-SMR-transporter	gnl\|CDD\|224987	COG2076, EmrE, Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism].	4.01948e-16
NZ_CP045920.1\|WP_153877240.1\|550820_552140_-\|fuconate-dehydratase	gnl\|CDD\|239440	cd03324, rTSbeta_L-fuconate_dehydratase, Human rTS beta is encoded by the rTS gene which, through alternative RNA splicing, also encodes rTS alpha whose mRNA is complementary to thymidylate synthase mRNA. rTS beta expression is associated with the production of small molecules that appear to mediate the down-regulation of thymidylate synthase protein by a novel intercellular signaling mechanism. A member of this family, from Xanthomonas, has been characterized to be a L-fuconate dehydratase. rTS beta belongs to the enolase superfamily of enzymes, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion.	0
NZ_CP045920.1\|WP_153877237.1\|548423_548873_-\|transport-protein-RbsD/FucU	gnl\|CDD\|226632	COG4154, FucU, Fucose dissimilation pathway protein FucU [Carbohydrate transport and metabolism].	1.3365e-40
NZ_CP045920.1\|WP_153877239.1\|549731_550700_-\|aldo/keto-reductase	gnl\|CDD\|381378	cd19152, AKR_AKR15A, AKR15A family of aldo-keto reductase. The AKR15 family includes Microbacterium luteolum pyridoxal 4-dehydrogenase (PLD), Pseudomonas sp. D-threo-aldose 1-dehydrogenase (FDH), and similar proteins. PLD (EC1.1.1.107) catalyzes irreversible oxidation of pyridoxal. FDH(EC1.1.1.122), also called (2S,3R)-aldose dehydrogenase, or L-fucose dehydrogenase, catalyzes the oxidation of L-fucose to L-fuconolactone in the presence of NADP(+). It is also active against L-galactose, and to a much lesser degree, D-arabinose. FDH (EC1.1.1.122), also called (2S,3R)-aldose dehydrogenase, or L-fucose dehydrogenase, catalyzes the oxidation of L-fucose to L-fuconolactone in the presence of NADP(+). It is also active against L-galactose, and to a much lesser degree, D-arabinose.	3.71788e-120
NZ_CP045920.1\|WP_153877234.1\|546854_547652_+\|FCD-domain-containing-protein	gnl\|CDD\|225097	COG2186, FadR, Transcriptional regulators [Transcription].	9.74662e-53
NZ_CP045920.1\|WP_153877231.1\|533935_537049_+\|sugar-isomerase	gnl\|CDD\|238517	cd01083, GAG_Lyase, Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen. These are broad-specificity glycosaminoglycan lyases which recognize uronyl residues in polysaccharides and cleave their glycosidic bonds via a beta-elimination reaction to form a double bond between C-4 and C-5 of the non-reducing terminal uronyl residues of released products. Substrates include chondroitin, chondroitin 4-sulfate, chondroitin 6-sulfate, and hyaluronic acid. Family members include chondroitin AC lyase, chondroitin abc lyase, xanthan lyase, and hyalurate lyase.	9.86283e-142
NZ_CP045920.1\|WP_153877232.1\|537282_541419_-\|hypothetical-protein	gnl\|CDD\|379625	pfam14498, Glyco_hyd_65N_2, Glycosyl hydrolase family 65, N-terminal domain. This domain represents a domain found to the N-terminus of the glycosyl hydrolase 65 family catalytic domain.	3.74104e-67
NZ_CP045920.1\|WP_153877241.1\|552318_553191_+\|FAA-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	2.95539e-86
NZ_CP045920.1\|WP_152817265.1\|528493_528784_-\|WXG100-family-type-VII-secretion-target	gnl\|CDD\|274862	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target. Members of this protein family include secretion targets for the two main variants of type VII secretion systems (T7SS), one found in the Actinobacteria, one found in the Firmicutes. This model was derived through iteration from pfam06013. The best characterized member of this family is ESAT-6 from Mycobacterium tuberculosis. Members of this family usually are ~100 amino acids in length but occasionally have a long C-terminal extension.	3.96895e-10
NZ_CP045920.1\|WP_153877235.1\|547629_547956_-\|QacE-family-quaternary-ammonium-compound-efflux-SMR-transporter	gnl\|CDD\|224987	COG2076, EmrE, Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism].	5.42595e-17
NZ_CP045920.1\|WP_152817271.1\|531651_532689_+\|GTP-3',8-cyclase-MoaA	gnl\|CDD\|234672	PRK00164, moaA, GTP 3',8-cyclase MoaA.	8.00762e-171
NZ_CP045920.1\|WP_152817281.1\|546515_546758_-\|MoaD/ThiS-family-protein	gnl\|CDD\|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	9.3814e-15
NZ_CP045920.1\|WP_153877229.1\|531244_531670_+\|molybdenum-cofactor-biosynthesis-protein-MoaE	gnl\|CDD\|238385	cd00756, MoaE, MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. Moco contains a tricyclic pyranopterin, termed molybdopterin (MPT), which carries the cis-dithiolene group responsible for molybdenum ligation. This dithiolene group is generated by MPT synthase in the second major step in Moco biosynthesis. MPT synthase is a heterotetramer consisting of two large (MoaE) and two small (MoaD) subunits.	4.62022e-42
NZ_CP045920.1\|WP_153877227.1\|527415_528351_-\|DUF4031-domain-containing-protein	gnl\|CDD\|226789	COG4339, COG4339, Uncharacterized protein conserved in bacteria [Function unknown].	1.07207e-29

>NZ_CP045920.1|WP_153877232.1|537282_541419_-|hypothetical-protein
MTSSNDALLGDMMSLPTLAHSPARGLVAASVATAALVLGGTLAAQAAPPADPGDLSELSEPSELSEPAAAAAGPTAEVPLRLTYGQPATDWETETLPIGNGALGASIYGGVAQGRLQLNEKSLWSGGPGVAGYDYGNYDRSTRPNALDDVRAKIEAEGQADPSWVAGKLGKPRTGYGSYQPFGELLLDVPGTEGYEDYERALDLNDAVSTVEYTVDGVTFTREYIASYPDDVIVAHLTADAAGAIDFTATYRSQMNGGTVTAEEGRLTLSGEVPGNGLAYNGQIQVLAEGGSVTDSGSDVIVAGADSATLIFSGGTEYAPVYPDYRAADPAAHVARVTAAVDAAAAKGWDALRAAHEADYHELFDRVALDLQGAPIDVHTDTALSRYTGATDRDRTLETLFFQYGRYLLISSSRDNSPLPANLQGVWNNSTGAPWGADYHTNINLQMNYWPALSTNLAETYTPYVEYIESLVPAGAASAEAILGMDGWMVNNETTPWGFTGVHDWATAFWFPEANAWLAIDVFRQYLYSGDEAFLADTAYPLLRKTADFWLDYLTVDGRDGSLVASPSYSPEHGPFTAGAAMTQQLATELLTAVVEAGQILDVDASFRDEVAGTLAQLDSGLHVSETSGRILEWKDVAIDDSVNATDPNHRHVSQLYALFPGNAISWAHTPELAEAAEVTLTDRGDGGTGWSKAWKINFWANLGDGSHAHKMLSEQLKNSTYDNLWDAHPPFQIDGNFGAASGVAEMLVQSNADGVEILPALPGAWRDGSVDGLRGAGGLTIGATWANGTGTQLRVTPDASGEVSVRSPLITGPIRVLGAGSPVEVEVADGKATWTGAAGTTYTIEPLTTMGLTGPTSVEQGAQPEVTVTLDGEVAGGTLGLAAGDGWVVGPACTRVEGPGEYTFTIAVPEDAAPGSATVTVTYATPDGTVTRDLDLTVVPSTRTRIDQAELTVAASSWQEASEYSHVDQAVDGDPDTIWHSQWSQPEPDKQPWLSVDLGSEYSEITLNLLPRQSGNTNGQLEDYRVYVSEDGATWGAEAVASGTMPNNRDLQSIELPREVTTEHVKIVWVSSYSDTSANFGSLAELNVNGVNGETPDPLPPLEVDPDTCDVVETPTITDVTGVEPVILPSGTSESDAGAALPAATTITDSDGTDHDVALTWDISDYDGTVAADYTATGSFELPDGVAQSDPATVLEVVTVVTVSPQGADGSDNTDGSDGSDGSDDTDGTDGTDQGADTGADGTDGTDGTDQGADTGADDTDDTDGSNDTDDSNGTDQGADAGGSDSGGTTDQGSGTDQGSDAGTDQGSGTDQGSDAGADQDGGAASGSDSAGGSGGDPIDDMPDTGVSSGAPLAFLSVAILAAGAVVLVLRRRSSVN
>NZ_CP045920.1|WP_153877231.1|533935_537049_+|sugar-isomerase
MVAVRAAPCRSQQPLDVIGDRVMSLSPSRRSFLLGASAALAVFATGGVQLPALAATTYEDALTRRRTFLTGGTVAADHPGLAAKRARIDARTKDLVDTFNRTPGRTHLWPGLRVGAASNTTEVANMGVTANQITELAIAWASPGSTYYRDASLLQDIHGACAFLSGQYRADRGRPGNWWFWEIGLPRQLADTLTLLGDQQPEKAPSLLAAADFFAPNPNRRTGSSLKETGANRVDKALACIVRGLLREDEDQIALGRDALSDTEGEGRNSLFGRVTSGDGFYSDGSFIQHSALPYSGTYGGVAISGVAAVMAMLAGSPWQVTDPDLSNLLAAVELTFAPFQWDVRTMDTTRGRAVSREASRDYDSGFAIASAVIVLAESAPADQRESFRALVKGWLERTTDQSVADNGQSLAASARSLEVVGDESLAARPPRIGITNTYNQERIVQHRGEWAAVVNTSSRRIGRYEWGNRENNHGWYQGDGMLFLYHTGDPAQYSADFWPTVDPYALPGITVNGEQRASGEGDGTGIPRAQNEYAGGLTVGDAIGTTAMDLTNATGTLRANKSWFHLTDSIVCIGSKISDTSGTGVRTIVENRGFATGALPAVSADGAPLTLTDDLAPARVVHVDGHAGILALAAPGRAEQRFGVRSQQRTGTWEAINSGGDTGGSSEAVARDYVRIEQAHESAGGWYAYQILPLADAARTAAAADAPQVVVVLADDDAHLIETGDGSRLGHFFAAGTWGGYTVTGACAIGLRRAPAATGGTAVAGAHLTEIVVAQPTKAGGTVSVTFPFDAPGTVAGVDEAITVVATSPLQLEVDVDARRGREHRLFFASLATPEPVTVHHRDEDGEAVAPDVVLTGELGEAFDAVPVEVEGYELTGTPANASGTFGDEPVSVVFVYARVAEPSPTDTASPTPTDTASPTPTDTASPTPTGTASPTPTGTGGSTPTPTGSAGGSPTASGSGGGRPGDDRPGGTGDSGPGRLPSTGAGVLGIGALAAATAGAGALLRRRQVMSGSEPDAPEPGSEASDGSADTTAAE
>NZ_CP045920.1|WP_153877230.1|532781_533864_+|DeoR-family-transcriptional-regulator
MVPDGRHWSSILRVSDDRGTAPRLAGERREAIAALARMHGVVRVSELADRYGVSHVTIRRDISALVDRGALTRIHGGARSTAGMVRAAAGDDQVRIGVILPASRYYFRELLEGIREGAARAGIAVVLAISEYDDGEERRLFERMLRAKVAGVLLATAAAEPETGWLDSSPVPVVLVERAGPDFDHARSDHEDGARIAVAHLVARGHERIMLAACSTTPTAARLLAGYRAELAAAGRDLLEPFDLPGEDASPTGRRARLHDLLRACAQQRASALILHPEGFALPLLEAAEDRAVAVPADLALVTYDDELAEFASIPLTAVQPPKRDVGSIAVDVLVRRLTRPGVARQRVTLLPRLVVRESS
>NZ_CP045920.1|WP_152817271.1|531651_532689_+|GTP-3',8-cyclase-MoaA
MGGISMSVNVSPELRGPLADRFGRVHRDLRISLTDVCNLRCTYCMPAEGVPWLARANILTTDELVRTAEIAAALGIVEVRLTGGEPLLRPDVVDVVGRMAAIEGEDGPLEVSMTTNALRLTKLAPALREAGLARVNISLDTLHPERFQQLTRRDRFDDTLAGIEAAVAAGFAPLKFNAVAMRGVNEDELVDLVRFALSKGGQMRFIEQMPLDAGHIWSRETMVTGEEILAQLETAFTLTEAPGRGAAPAEKFLVDGGPGTVGVIRSVTRPFCGTCDRVRLTADGQLRNCLFARTESDLLGVIRGGGDDDDIARLMHTCIAGKLPGHGIDDPGFLQPDRPMSAIGG
>NZ_CP045920.1|WP_153877229.1|531244_531670_+|molybdenum-cofactor-biosynthesis-protein-MoaE
MTDSLVRLSNEPLDVAAHLDHAGADWVGGVASFIGTVRNHSPDVDGEVVQLDYSAHPSAERVLAEIVAEVTDAHPGVRLAVSHRIGTLYIGDLAIVVAAGSSHRAEAFAACREAVETVKKKLPVWKRQVLTDGSYVWVGSA
>NZ_CP045920.1|WP_152817269.1|530760_531252_+|MogA/MoaB-family-molybdenum-cofactor-biosynthesis-protein
MAPQDRIRPVVITVSTRCAHGRATDRSGPRLVECLAGAGYPDADLVVVPDGVEPVRAALGAALGGGSRLVITTGGTGITASDLTPEATEPLLHAHLPGIPEAIRRDAAARAPHAVLTRGLAGTHGDAFVLNLPGSPAAVTDAMATVGPLLPHILDQLRGGTHD
>NZ_CP045920.1|WP_153877228.1|529302_530637_-|hypothetical-protein
MGAMNASAWLLPAWRRSLAVIGASAEDERIEAAGRRLIERWSDPDRKHHNLRRLVSVLARVDELAAETHGPDLVRVAAWYHGAVFRMDDSHVYSRRGGIDEIASSQLARSELTGLGVPEESIARVVELIHALARHHVPDGDLDAMALCDANLGGLAVEPQKYATYRREVREEYSEVPDLDYFRARIAIIEKLLGRAKLFTSPLGQAWEERARENLTAERARVSAQLAKLSGAPAPTAEPPAREMGAHAERSFFAGAGPGAGRSDPDRPAGTFAPLPSGSIPRIPGSQGSQGAQGSTDSTGSRVPSGSQGSHGSQGPSGSQGSPVPSGSQGSHGSQGPSGSPGSPGSPGSPGSPATPRDRADTRSVGSVSSPASPTEELRPLVKDYPKGRPLGPKLRRIDALPRSAEARGPSGSADAAAPPERGGAPSTADSPDEGSTMTRPPRD
>NZ_CP045920.1|WP_152817265.1|528493_528784_-|WXG100-family-type-VII-secretion-target
MARFEVDSAEVARGALAARHHGGTIRAEVATMMQLLLSLEASWQGSASLAFREAIQQWRLTQQQVESSLDALSASLDVSARQYDDAESANTRMFLH
>NZ_CP045920.1|WP_153877227.1|527415_528351_-|DUF4031-domain-containing-protein
MAILIDPPMWPAHGTSFSHLVSDSSLTELHEFARRAGVPGRAFDEDHYDVPSARYRELIELGARAVDGRELIRALRASGLRVPAHARAGGALPALERRWLDLWTDRPDLGEHLLGRWNEEHRHYHGPAHLLAVLRRLDDLTRRGTPGLQAAGERAPAPSRRVRLAAWFHDAVYDGVPGQDEARSAELARQMLAENVPAGRLARQVADLVLCTTDHRIPAGLEAELRGDAALLIDADLGVLAEPAAGYARYVAAVRADYAHVGEQAWRAGRAAVLDHLLGADPLFRTDWAREHWTQRATENLRRERATLGAD
>NZ_CP045920.1|WP_153877226.1|526138_527377_+|MFS-transporter
MVSLTRRATVAIDRAERPLFGAVLLGAFFGVIGQNTVGMIGPFLSAEFSIDATILGTLNAFTFASMALGSIILGWVAGRAGLRQSLRWGVGFIVVGSLIGAAGDGMTAFALSRIVTGIGLGGLSTNSVATLTALVSATARGSAVSLLNVAAGGLGNVAAFLFGLGIVGVFAAPEQAGGHGWRVILIAIAVLGVIVWLTYRAIPDVTKGAAPAGAPAQASADSGALRPPLVRAAASYFVTAGCTLTVLTFLPTLLASSGGVSSSESLLLAAIVQVGGLVGACFSLLFAANGGVKRYVIGAGTLCVGVCLAIVLQGHHIAVLMTSALLFQLAGVFAVTLYWRWFPMLFSSSERPRGMGIIIGSGSLGAVGLTWAGGVLLDRGGPALLFGGIGCAYLILLVCVSFVPERPSFDRH
>NZ_CP045920.1|WP_153879126.1|545751_546519_+|inositol-monophosphatase
MKHAADTVIMPRWRSLSDDQVEEKNPGDLVTVADRESEQVITAELRSAHPKAMILGEEAYAADPGILEDFQRAEHAFTVDPIDGTSNFVHGSRDFAVMVAELRAGDVVRSWIWQPAHGAAYEAAAGAGATRNGAVLPRRELDPDTATWRGATARRGLLARDHVPLAQLREAAWCCGVDYPHVATGDLDYLVYSKVWPWDHAPGSLLVREIGGRSIRKDGSSYSPAAPIGRWLLAGADASAPTALSYLEADLTEEN
>NZ_CP045920.1|WP_152817281.1|546515_546758_-|MoaD/ThiS-family-protein
MATIQVRYFAAAADAAGVTAETLTVAEAATVADLRDAMIAEHPGLAGVIQLCSFLVDGQAAEPADPIGATVDVLPPFAGG
>NZ_CP045920.1|WP_153877234.1|546854_547652_+|FCD-domain-containing-protein
MALTDRAIGEIKAMIQAGDLQPGDRLPPEGELSERLGLSRSSLREAVKALEAMRVLDVRRGDGTYVTSLEPRLLLEAMSFVLDFHQSHAVLEVFEVRRILETSSAALAADHATPEQVAGLRESLAASRAASDIEDLVEHDRDFHARIADSTGNGYLAGLLGTVSDKTVRARIWRGLTQDRAVDKTLAEHEAIIAAIETGNSELARALMLVHVAGVEDWLHANVDDSTGQVAEPESVEPESAEPDEPEGADGTGLEGAGVSGHRAR
>NZ_CP045920.1|WP_153877235.1|547629_547956_-|QacE-family-quaternary-ammonium-compound-efflux-SMR-transporter
MTALAWAFLVAGIVFEVAGTVALRLAIDRGRGWYAMVAVGYLLAFTLVSLALGEGMPLGVAYGIWTATGVALTAVLSMVLFREPLTRLMAVGIGLVAAGVLLIELGAR
>NZ_CP045920.1|WP_153877236.1|547952_548375_-|QacE-family-quaternary-ammonium-compound-efflux-SMR-transporter
MSGRSPAPRAWYLLAGAIGSEVAGSLSLRGALDRPGLYVVVVAGFLTAFALLSLSLRAGMRLGVGYGIWGACGVALTAALSTLLFEEPLTPLMIAGILVVIAGVLCIELGSQAAARSSGPSGPAEPGGTGTGATGSGEVR
>NZ_CP045920.1|WP_153877237.1|548423_548873_-|transport-protein-RbsD/FucU
MLTGIHPILTGRVLRMLDELGHGDSLVVADANFPAHTLAADALDLPGLASPQVLTAVRTVVPADDYEGPSVQLMEAEPGIDVGVQRELRAAAGVPADRVELVERFEFYERARAASAIIRTGELRPYGNVILRKGVVSVAAQSHAPGNGS
>NZ_CP045920.1|WP_153877238.1|548874_549735_-|amidohydrolase-family-protein
MRTIDAHLHLWDLAGGGYTWITPELGPLHRTIGPAEARAFHEAAGYDGAILVQADDTRADTDAMLAVAAAHDWVLGVVGWVPLTDPEEAAAQLARYAGRPAGGRLVGIRQLIHADPDPGVLDRAAARETLALLAGAGLPLEVPDAFPRHLDQAARVAADLPGLTVVIDHLGKPPAEAGAFAEWAAQLRAAAEQDNVVAKVSGLHHGGRLLPARVLDAAWNVALEAFGPGRLMLGSDWPMPMLGGDAALADDVARRDRLLATLDARDRGSICSGTATRVYGLPTDWT
>NZ_CP045920.1|WP_153877239.1|549731_550700_-|aldo/keto-reductase
MNALTSIDGRLGFGAAGFGNLFAERSKEQVHQIAEAAWDAGMRYFDTAPHYGLGLSERRLGAFLATKPREEFVLSTKVGRLLTPVSNPTGALDLANDFHVPADHERVQDYTAGGIRRSIEDSLERLGLDRIDIAYLHDPDKAEIGLDAALDQALPALEQLRAEGIVEAVGVGSMSTAAMVAAVRRADLDVLMCAGRYTLLEQGAAAELLPLCLERDVRVVTASIFNSGLLARATPSRSGRYEYGAVPPELYERAVAIAAVCARHGVELPTAALQYTLRHPAVAAVVVGISRLEQVAQNNERMAVPVPDRLWSDLAAEGLIPA
>NZ_CP045920.1|WP_153877240.1|550820_552140_-|fuconate-dehydratase
MSTIIAVDLADVRFPTSLSLDGSDAMNPDPDYSAAYLTIRTDTPDPADAGHGFVFTIGRGNDVQLAAIEALADHIVGRNVEELLADLGAASDLLTRDSQLRWLGPEKGVIHMAIGAVVNALWDLKAKRAGLPLWKLLATMSPAELVDLVDFRYLSDALTRDEALEILEAAEPGRAERVAHLEQAGYPAYTTSPGWLGYSDEKLARLCAEAIAEGFTQIKLKVGADLDDDVRRMRIARDVCGPDFPIAVDANQRWDVAEAIRWITALAPFDPHWVEEPTSPDDVLGHAAIARAIAPIPVATGEHVANRVVFKQMLQAKSLSYLQIDSARVGGVNENIANLLLAAKFGVPVCPHAGGVGLCEAVQHLSMFDYVAVTGTMEGRVIEYVDHLHEHFVVPTVIERGRYRAPSAPGTGMEMRAESILANTFLPPAKLGDDALRPA
>NZ_CP045920.1|WP_153877241.1|552318_553191_+|FAA-hydrolase-family-protein
MRFARLGPQGSEIPVLVTEEAHYDLRPITADIDGEFLEHRQGEVAAALAAGTLETIDPAGLRIGAPIARPTAIVCVGMNYAAHAAESGSAPPELPVIFFKHPNTLGGPDDAVEIPRGSEKTDWEVELALVIGKRASYLDSVAEAADHIAGYTVVDDLSERTFQLEVSGGQWSKGKCSPGFSPTGPVLVTADEVDAGNLRLRSWVNGEPRQDSVTADMIFDTRYIVWHLSQFMALEPGDLVITGTPQGVALSGRFPYLSAGDVVEVEIEGIGRQRHAFVEVGSAPMAGGAA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP045920_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045920_3

1105168-1105303

Orphan

Consensus_repeat	Method
CAGCACAGGTGTGTCCACCGCTCCCGGATCCGTCGAGGTCGCCGCCGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045920_3

>merge|NZ_CP045920|3|1105168-1105303|CRISPRCasFinder
CAGCACAGGTGTGTCCACCGCTCCCGGATCCGTCGAGGTCGCCGCCGGGGCCGGCGAGACCGTCCTGCCCGGAATGGGCGGGACCGTCAGCACAGGTGTGTCCACCGCTCCCGGATCCGCCGAGGTCGCCGCCGGG

>NZ_CP045920|3|2|1105168-1105303|CRISPRCasFinder
CAGCACAGGTGTGTCCACCGCTCCCGGATCCGTCGAGGTCGCCGCCGGG	GCCGGCGAGACCGTCCTGCCCGGAATGGGCGGGACCGT
CAGCACAGGTGTGTCCACCGCTCCCGGATCCGCCGAGGTCGCCGCCGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045920.1\|WP_153877581.1\|1087747_1088170_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045920.1\|WP_153877595.1\|1108812_1110462_-\|FAD-binding-dehydrogenase	unknown	unknown	gnl\|CDD\|183782
NZ_CP045920.1\|WP_152909531.1\|1084614_1085025_+\|pilus-assembly-protein-CpaE	unknown	unknown	unknown
NZ_CP045920.1\|WP_153877587.1\|1099338_1101918_+\|alpha-glucan-family-phosphorylase	unknown	unknown	gnl\|CDD\|340852
NZ_CP045920.1\|WP_153877601.1\|1115804_1116911_+\|tRNA-2-thiouridine(34)-synthase-MnmA	unknown	unknown	gnl\|CDD\|234664
NZ_CP045920.1\|WP_153877599.1\|1113612_1114608_+\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	unknown	unknown	gnl\|CDD\|224936
NZ_CP045920.1\|WP_153877591.1\|1106481_1106703_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045920.1\|WP_152909536.1\|1091546_1092569_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045920.1\|WP_153877597.1\|1110546_1112817_-\|glycogen-debranching-protein-GlgX	unknown	unknown	gnl\|CDD\|131155
NZ_CP045920.1\|WP_153877600.1\|1114617_1115808_+\|aminotransferase-class-V-fold-PLP-dependent-enzyme	unknown	unknown	gnl\|CDD\|224029
NZ_CP045920.1\|WP_153877583.1\|1088173_1089811_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|173412
NZ_CP045920.1\|WP_153877598.1\|1112815_1113616_+\|electron-transfer-flavoprotein-subunit-beta	unknown	unknown	gnl\|CDD\|224997
NZ_CP045920.1\|WP_153877586.1\|1092588_1093503_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|225660
NZ_CP045920.1\|WP_153877594.1\|1107666_1108794_-\|tryptophan--tRNA-ligase	unknown	unknown	gnl\|CDD\|234866
NZ_CP045920.1\|WP_153877593.1\|1106858_1107578_-\|HAD-hydrolase-like-protein	unknown	unknown	gnl\|CDD\|319798
NZ_CP045920.1\|WP_153877589.1\|1101925_1103101_+\|NAD(P)-binding-protein	unknown	unknown	gnl\|CDD\|235874
NZ_CP045920.1\|WP_153877585.1\|1089948_1091550_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235906
NZ_CP045920.1\|WP_152909618.1\|1097097_1099242_-\|DUF3416-domain-containing-protein	unknown	unknown	gnl\|CDD\|200482
NZ_CP045920.1\|WP_153877580.1\|1085096_1087646_-\|aminopeptidase-N	unknown	unknown	gnl\|CDD\|274121
NZ_CP045920.1\|WP_153877602.1\|1117003_1117948_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236090

Protein	Function_ID	Function_description	E-value
NZ_CP045920.1\|WP_153877595.1\|1108812_1110462_-\|FAD-binding-dehydrogenase	gnl\|CDD\|183782	PRK12834, PRK12834, putative FAD-binding dehydrogenase; Reviewed.	0
NZ_CP045920.1\|WP_153877587.1\|1099338_1101918_+\|alpha-glucan-family-phosphorylase	gnl\|CDD\|340852	cd04299, GT35_Glycogen_Phosphorylase-like, proteins similar to glycogen phosphorylase. This family is most closely related to the oligosaccharide phosphorylase domain family and other unidentified sequences. Oligosaccharide phosphorylase catalyzes the breakdown of oligosaccharides into glucose-1-phosphate units. They are important allosteric enzymes in carbohydrate metabolism.	0
NZ_CP045920.1\|WP_153877601.1\|1115804_1116911_+\|tRNA-2-thiouridine(34)-synthase-MnmA	gnl\|CDD\|234664	PRK00143, mnmA, tRNA-specific 2-thiouridylase MnmA; Reviewed.	0
NZ_CP045920.1\|WP_153877599.1\|1113612_1114608_+\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	gnl\|CDD\|224936	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion].	3.23079e-66
NZ_CP045920.1\|WP_153877598.1\|1112815_1113616_+\|electron-transfer-flavoprotein-subunit-beta	gnl\|CDD\|224997	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion].	2.81146e-56
NZ_CP045920.1\|WP_152909618.1\|1097097_1099242_-\|DUF3416-domain-containing-protein	gnl\|CDD\|200482	cd11344, AmyAc_GlgE_like, Alpha amylase catalytic domain found in GlgE-like proteins. GlgE is a (1,4)-a-D-glucan:phosphate a-D-maltosyltransferase, involved in a-glucan biosynthesis in bacteria. It is also an anti-tuberculosis drug target. GlgE isoform I from Streptomyces coelicolor has the same catalytic and very similar kinetic properties to GlgE from Mycobacterium tuberculosis. GlgE from Streptomyces coelicolor forms a homodimer with each subunit comprising five domains (A, B, C, N, and S) and 2 inserts. Domain A is a catalytic alpha-amylase-type domain that along with domain N, which has a beta-sandwich fold and forms the core of the dimer interface, binds cyclodextrins. Domain A, B, and the 2 inserts define a well conserved donor pocket that binds maltose. Cyclodextrins competitively inhibit the binding of maltooligosaccharides to the S. coelicolor enzyme, indicating that the hydrophobic patch overlaps with the acceptor binding site. This is not the case in M. tuberculosis GlgE because cyclodextrins do not inhibit this enzyme, despite acceptor length specificity being conserved. Domain C is hypothesized to help stabilize domain A and could be involved in substrate binding. Domain S is a helix bundle that is inserted within the N domain and it plays a role in the dimer interface and interacts directly with domain B. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.	0
NZ_CP045920.1\|WP_153877597.1\|1110546_1112817_-\|glycogen-debranching-protein-GlgX	gnl\|CDD\|131155	TIGR02100, Glycogen_operon_protein_GlgX_homolog, glycogen debranching enzyme GlgX. This family consists of the GlgX protein from the E. coli glycogen operon and probable equivalogs from other prokaryotic species. GlgX is not required for glycogen biosynthesis, but instead acts as a debranching enzyme for glycogen catabolism. This model distinguishes GlgX from pullanases and other related proteins that also operate on alpha-1,6-glycosidic linkages. In the wide band between the trusted and noise cutoffs are functionally similar enzymes, mostly from plants, that act similarly but usually are termed isoamylase. [Energy metabolism, Biosynthesis and degradation of polysaccharides].	0
NZ_CP045920.1\|WP_153877600.1\|1114617_1115808_+\|aminotransferase-class-V-fold-PLP-dependent-enzyme	gnl\|CDD\|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	1.70535e-141
NZ_CP045920.1\|WP_153877586.1\|1092588_1093503_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|225660	COG3118, COG3118, Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones].	9.00355e-42
NZ_CP045920.1\|WP_153877594.1\|1107666_1108794_-\|tryptophan--tRNA-ligase	gnl\|CDD\|234866	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed.	4.24382e-121
NZ_CP045920.1\|WP_153877593.1\|1106858_1107578_-\|HAD-hydrolase-like-protein	gnl\|CDD\|319798	cd04302, HAD_5NT, haloacid dehalogenase (HAD)-like 5'-nucleotidases similar to the Pseudomonas aeruginosa PA0065. 5'-nucleotidases dephosphorylate nucleoside 5'-monophosphates to nucleosides and inorganic phosphate. Purified Pseudomonas aeruginosa PA0065 displayed high activity toward 5'-UMP and 5'-IMP, significant activity against 5'-XMP and 5'-TMP, and low activity against 5'-CMP. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.90783e-59
NZ_CP045920.1\|WP_153877589.1\|1101925_1103101_+\|NAD(P)-binding-protein	gnl\|CDD\|235874	PRK06847, PRK06847, hypothetical protein; Provisional.	6.11665e-47
NZ_CP045920.1\|WP_153877585.1\|1089948_1091550_+\|hypothetical-protein	gnl\|CDD\|235906	PRK07003, PRK07003, DNA polymerase III subunit gamma/tau.	4.27636e-07
NZ_CP045920.1\|WP_153877583.1\|1088173_1089811_-\|hypothetical-protein	gnl\|CDD\|173412	PTZ00121, PTZ00121, MAEBL; Provisional.	5.03624e-11
NZ_CP045920.1\|WP_153877580.1\|1085096_1087646_-\|aminopeptidase-N	gnl\|CDD\|274121	TIGR02412, Aminopeptidase_N, aminopeptidase N, Streptomyces lividans type. This family is a subset of the members of the zinc metallopeptidase family M1 (pfam01433), with a single member characterized in Streptomyces lividans 66 and designated aminopeptidase N. The spectrum of activity may differ somewhat from the aminopeptidase N clade of E. coli and most other Proteobacteria, well separated phylogenetically within the M1 family. The M1 family also includes leukotriene A-4 hydrolase/aminopeptidase (with a bifunctional active site).	0
NZ_CP045920.1\|WP_153877602.1\|1117003_1117948_+\|hypothetical-protein	gnl\|CDD\|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	6.96369e-09

>NZ_CP045920.1|WP_153877589.1|1101925_1103101_+|NAD(P)-binding-protein
MSHAAVVVGGGIAGLAAAISLARAGWEVTVAERAATPTELGAGFAMARNAVAAFRALGFDDDTVGLLGYRTRAAGTWAFDGRPILTLADDARTRAAVALIGVNRRRIHHVLLERARAVGVDIETGLEVATLSVGAPGGAPAVVAGREADLVVGADGMFSAVRDALFSSHRLTYSGYSSWRALTARTPEVTTLRQFWGPHAEFGLMPVSEELTYWYGYVAMPSRTRLDDELVAARERFAGWARPVLDVMDATEPGAVMRHDVYHLPGGLPSYTHGRVVMIGDAAHGFLPTMGQGVATALEDGACIGLFIGHPVAAGGRLAPALAEFDAVRRPRSRALGRAAMATARIGAHLGGGRRQSVRNALMRVTPAGLVNRGADAAMGWQPPPPAAPRF
>NZ_CP045920.1|WP_153877587.1|1099338_1101918_+|alpha-glucan-family-phosphorylase
MRAIRRFTVRPMLPEPLAALDDLAVNLRWSWHTPTRELFESIDADLWRSLHGDPVTLLGSLSSDRLDALAADDAFVARVRHLAEDLADYLRERRWYQGEAQRRADAGEAAPPAAIAYFSAEFGITGALPQYSGGLGILAGDHLKSASDLGMPIVGVGLLYGAGYFRQSLTRDGWQAETYPVLDPDNLPLTLLRDGEDRPVRVSVPLPGGRVLNAQVWRADVGRVPLLLLDSNVVENDDAARHVTDRLYGGTSEHRLQQELLLGMGGVKALREFSRLTGAPEPEVYHCNEGHAGFLGVERMREYIEATGADVDTAVEAVRGGTVFTTHTPVPAGIDRFESSLVRDYFSSGAEVPGVPVERILALGAEDYPGGDPGVFNMAVMGLRLAKRANGVAKLHGKVSRGMFHHLWSGFDVTEVPITSITNGVHSGTWVDPVFAEAQAECFTDAQVSDGSGWLSDRIDNATLWELRGRLRSALVRDARERVRKSWSQRGASPAELGWVGEVLDEDVLTIGFARRVPTYKRLTLMLRDPERLRALLTDPDRPIQIIVAGKSHPADEQGIRLIQQLVQFADSEDVRKRIVFLPNYDIEMAQTLLPGCDVWLNNPLRPLEASGTSGMKSALNGGLNLSILDGWWDEMYDGHNGWAIPTADGVEDPERRDDLEATALYDLLENTVVPRFYDRTDGLPLRWLENVRHTLATLGPKVQATRMVKDYLAVMYGPTAESARALSSVEAAGALAAWKNRVRAAWHSVRVDHVESEGLHETVNVGDRLNVRAFVTLGDLDPVDVQVQMNYGRVRENDELVDFRTVLLDHTETYEGGRHQFALDYALEEAGPFGYTVRIVPTHPEMASDAELGLVTGA
>NZ_CP045920.1|WP_152909618.1|1097097_1099242_-|DUF3416-domain-containing-protein
MPAGESRRTLLTNRHFVGRFSSVTTTPEPRPTALPGFPPAGPSPEPAPAAGIGRIPVLDVGPVVEGGRWPTKAVVGEVVPVRATVFRDGHEYVSATAVLIDPEGRDHSALTMRPGTPGLDDWHAEFVPDRVGRWYFRVEGWSDPLATWAHDAVIKVDADVDTELMLTEGALLLEAAAARPGLPAGVVAVLMDAVAGLRDSARPAAARLAAGTDARVRSALAAHPVRRFVTASATYPLQVHRREALFSSWYEFFPRSEGATFDEASGTWTSGTLRTAAERLPGIAAMGFDVVYLTPIHPIGSTNRKGRNNTLTCEPGDPGSPYGIGAADGGHDAVHADLGTFDDFDDFVARARGLGMEVALDLALQASPDHPWAIDHPDWFTVRADGTIAYAENPPKKYQDIYPLNFDRDPEGIYEAVRDVVYTWIDHGVTAFRVDNPHTKPLTFWERLLAEVASTHPHVIFLSEAFTKPAMMRALALIGFHQSYTYFTWRNTKEELSEYLAEVAGDSGAVLRPSFWPTTHDILTPYMQQGGQAAFAIRAVLAATGSPTWGIYSGYEFAESVARPGAEEQIDNEKYEFKPRDWTRAEHIGLATLLTRLNQLRAAHPALQQLRNLTVHGTTDDAIVCFSKRIAAEHSPTGTDDVIIVAVTTDPFATREGRLFLDMHALGLHHEATFVAEDLLSGDQYLWDRTPFVRLDPHGNCAHIISVRSSGGRV
>NZ_CP045920.1|WP_153877586.1|1092588_1093503_+|tetratricopeptide-repeat-protein
MTQHDPAGLNLRGAVDLAALTAPKADPVDAPGGLVIEVTAQSFADAVQQSMDVPVVLDLYSTRSPASVELSGVLVDLVKEFAGRFVLARVAVDANPEIAQALQVQSLPTTVAVLKGQPVPLFQGAHPIDQVRSILTELLRVAAENGVTGTVAAEEDDVPPAPPEPELPPHIQAAYDAIENDDLDAATAAFTQALAADPGDAEARAGLAQVTLLTRLAGVDPAAALNAARDASPGDAATQLLAADVELSTGRSAAAYDRVLAVIRATAGDDRELARLRLLDLFTLAPEGSPEVAAARRQLALALF
>NZ_CP045920.1|WP_152909536.1|1091546_1092569_+|hypothetical-protein
MNARRIVAATATGMVILLGSAGLTGCAVPVPQSTPEPESTTVYPVLDEGRLDRVLASVQTSLADADAALDPDLLPPRITERAEAVRAAEYRLAKATKDDEEPYTPQPLGTDDVAAVVAATEDWPRTVMVATTPPAGSNAPRLLVLTQQEPRDDYSMVGWVRLLPGVSTPTVAASEIGVDPVAPDDPGLLIAPDEVAAAYAETVEKGDKADSADLFADDIYRTALRDEVKAQQKSLEVAGTVKNKVTAQDGVAALATADGGAIVYAGLTSTMTYERTVARSTMKVGSQYAALNDGEDEVDESITGSYLHMIAFYIPPADAGEDAQVSVLGAERVLTKVTAK
>NZ_CP045920.1|WP_153877585.1|1089948_1091550_+|hypothetical-protein
MEMPGRVVVAVLVPVVLTGNYVADLAAGERLRQGVLRTVLRRIIAIALIVVGLAGIAGAIGSATVWKPATVVTLDLPATPDVPYVITRPGALTAVNDSVGVTVVAADSTEPVVLALGRAGDVTAWVGDSPHWVITGLQDWDHLSYSVGAPAGEPTDDATAGPTEEPTGDPDAADESAPADPANPAGSDLWIDQVEGVGEIQYTWSKVPGSWSMLVAGDGSGPAPQVELTWERDVPTPLLVPGIIGGALLLLIGLALLSADLLARREARRAPAADSYEPELTAQLQAIDPDRPLTRRELREAERARGRRGAAGAPSQQRSDATEVIPAVGGRSAEESAAAELAAWAGGAAAGSGAPARAAGDPAARVDPADLAVPAFLVPTTAPATDTAEPAEPAGTAGTTAPRWPALERTETIPAVSLVEPLEPRESAAPSEPAAEPVEPAAPAQTRRRWWRRRRTDGEPGPGEGPTRTVAASSLPPAEPDEPEPNDSEPNPRASGASWRATWGMGAAERPGHEPGEPDDGEPDDAGDSEEKR
>NZ_CP045920.1|WP_153877583.1|1088173_1089811_-|hypothetical-protein
MADEQPMFPVVMRGYDRAQVDEQLHGLTRQLHEARAQVEALDAAAVTMSGQLAETQALLQENEKPSYTGLGARIEQLLRSAEEQSAVLIGQAQTQARDIVERAQHQADSLAGQAESEAADVISAARRDAEARVAATASQVDGVLEAAQRRAEELVGSAEREAARITSAAATEVSERTASLERELGTSRASAERELTEARVTAEQEARELTATAEEAATALREQAKAEAQQLRSDAAREAELTRATAETAAQELIAAATTEAGSVRAVVAAERDEADVLLARRHEEAEQQDSARHEQAKAETTAMVADAQEHARAAETRVATALDKAEEIRSTAEARAEQILTAARAASDRITREAKEDADQLRTETVARVDRERRTAQSELDVLNQQRESITTYLDELRGLLGTGDDSGATALANAVPYEEYASPTDSAGPAEPTGSVGSVGSVGSVGSVGSVGSAGSAQSAASAATVESAPAGSSAASVPSVESVESVESVDSVDSVGSPATDDSNDTANTGDTADSNDTGDTGDTADDSEAESTAAADRTRSS
>NZ_CP045920.1|WP_153877581.1|1087747_1088170_-|hypothetical-protein
MTRAEDWRAERTRAAAEHAARLEARQAAEHAEAAEFIERFLERARAARLPAEPLRVQGYGGRGSARTPFTGWYLRRDRRAALGEEGDFYVLTAPLSVLDRIRGVRPEPVPAPLVLGQGGKDGESIDLVDALERLLPGWRG
>NZ_CP045920.1|WP_153877580.1|1085096_1087646_-|aminopeptidase-N
MPGTNLTRAEAHARASLLTADSYDISLDLTVGETHFLSTTVLRFRSREEEASTFVDLVDASDLEITFNSERLDPARVYRDSRIELTGLRGENELTVRARLPYSRTGEGLHRFVDPADDRVYLYSQFEVPDARRVYANFEQPDLKSVFTFTVTAPAHWVVVSNAPSPTPEPAGGAGEGTAIWRFEPTKRMSTYITAIIAGEYHCVHHSYEGAGGEIALGHYCRRSIKEHLDLDELLEVTKQGFEFFEHTFGVPYAFGKYDQLYVPEYNMGAMENAGAVTFRDEYLPRSRQVHAFYEQRANTILHEMAHMWFGDLVTMKWWDDLWLNESFAEWASHHAMAHATKYTDVWTGFTNARKNWAYRQDQLPSTHPIAADNVDLEAVEVNFDGITYAKGASTLKQLVHWVGEEEFVTGLRRYFAEHAWGNTEFADLLEALEAASGRELGTWAEEWLKTSGVNTLSPEFSLAGDDYASFAVRQRASEDFPTLRRHRIGIGLYDLTGGRLELRERLEVDIDGELTTIAALAGVRRPDLLLLNDGDLTYAKIRLDERSLATAIAHIDVVSDSLARALLWGAAWDMTRDGQLRARDFVTLVLAGAGSETDSTAVARLPMYVRTAVEYYSDPDHRDELRARWEAGLVALLEGAEPGSDHQLSFARALAGIAHSPSALDLLAGLLDGSRGLAGLTVDTDLRWTLVVALARAGVHGEAEIDAELARDNTISGRERAALARAVRPDAASKARAFHDAMVRDDLPNETQRQIAAGFATPGQGEYLAPLLEEYLTAADTLWEEKGVQRASTALELMFPMPLASPEVLARVTEWLQTSPANPAAKRYVREGAADMARALAAQAFDAG
>NZ_CP045920.1|WP_152909531.1|1084614_1085025_+|pilus-assembly-protein-CpaE
MISDDHARDLRDSGLAWHPAPGDRFRVEAAALGEEVFILSDMVIEARAHPTGTVLAFNGTTEWALDSVAMEQALWLPREDQLRAFLGEAFRGLHRTGDGFRVRTRLGDEPAAAFTAADPEDAYAAALLDLLHRAID
>NZ_CP045920.1|WP_153877591.1|1106481_1106703_+|hypothetical-protein
MTSVTNDQGSAMPQEPKKQAGRSPAVWFFVAAVFVVVLPTLPDRLNFPLNPIAAWVAGAVLTLIGFWVLLRRR
>NZ_CP045920.1|WP_153877593.1|1106858_1107578_-|HAD-hydrolase-like-protein
MGVGLPSGVSHVPIASLPQSALTSLEPTAVLFDLDGTISDSGAAITSAVAEALAAGDYPAISQADLLHFVGPPIRDGFREFGGVAEEDLDRVVAAFRPLYEGRMLAPAFEGMPELVRALHSRGVPLALATSKRRALAMQIVEHSGLTEYFTAQCGASDDGTRAWKADIVEDTLAALRAEGVDVSRAVMVGDRDHDVNGAITHDILSVFVAWGYGTDEERDGASAVATDVGELAQLLGVS
>NZ_CP045920.1|WP_153877594.1|1107666_1108794_-|tryptophan--tRNA-ligase
MSSESPANPVNVVPDAQPEDVLSDDIEKSLQRSVARSEEIEREIAADPSTFRVLTGDRPTGRLHLGHYLGTLANRVRLQDAGVETVLVVADYQVIMDRDDAGPLAERVRGLVTDYLAAGIDPERTTIFTHSSVPALNQLVLPFLSMVTDSELKRNPTVKAEHEATGGRPMSGLLFTYPVHQAADILFCKANLVPVGKDQLPHLEATRVVARRFNEKYARTFPLPEALLSRTANVLGLDGEKMSKSRGNTIELGMTADQTAKQFKRAVTDSDRHITYDPIGRPTVANLLQIAAACSGDDPARIAAEIGDGGGGGLKAVVTEAVNEHLAPLRARRLELEADPGYIASVLAAGNKRANEIADATLDEVRAAMGMVYGA
>NZ_CP045920.1|WP_153877595.1|1108812_1110462_-|FAD-binding-dehydrogenase
MVDADVIVIGAGLSGLVTATRAAARGRRVIVLDAEPTAALGGQAWWSFGGLLMVDSPEQRRLGVHDSPELAFSDWLGSARFADGADRGRGPDRFGYEWAQRYVEFAAGPMRAWLHGLGVRWFPLVQWAERGGYPAGGHGNTVPRFHVTWGTGPAILAPFVSAANSARADGLLEFRFRHRVVELVRTGTAVTGVRAQVLTPSPAGRGEQSSAEVTGEVELSAGAVVIAAGGIGANHDLVRELWPSGTLPTTLLSGVPDSTDGSMQTVAAGAGAALVHTDRMWHYPEGLPMPAPVWNRHGIRILPGPSSLWLDADGNRLPAPLFPGFDALGALEHITGRGDEHSWFVLNRTIMETEFALSGSDMNPDLTGKDVPLLLKRVTPGAVGPVAEFARHSPEFVWADSPAELAAGMNALVGDERIDGARLAGLVSLRDAQVASGLGKDPQVVATAAARRFWVDRRMRVAPPRPLTTPRDGPLLAVRLHVLTRKTLGGIHTDGRARVLDPAGAVLDGLFAVGEAAGFGGGGIHGHRALEGTFLGGCLFSGRVAAEAV
>NZ_CP045920.1|WP_153877597.1|1110546_1112817_-|glycogen-debranching-protein-GlgX
MLLACHAHLDGRYRGDGSSSWSGCGKGACVSSRSEVASDQVAAATARFPHRFGVHCRDGGVDVAVYAPQAEGVYVCFLDRDDSDHTAAERPWREHRVRLLRSHHGVWTAHVPGIEPGRRYGFRAHGATDRAGGRGFNPEKLLVDPYARGITGSLTLDPRVYGWDEDGRPIPGDSAPFVPHGIVMPAPEPARGPRPYVPWAQTVIYEAHVRGLTRKLPGVPADLRGTYAGLAHPATIAHLQRLGITAVELLPIQARLDEVALAERGATNYWGYNTLGFFAPEPGYATAAAQAAGPQAVLAEVTEMVELLHEAGIEVLLDVVYNHTCEGGIDGPMISWRGLDEGGYYLHAEGDATNYLDMTGTGNTLDFANPRVVELTLESLRYWAEVVGVDGYRFDLAVTLGRFGTRFDSLHPLLVGLVTDPVLRHLKLIAEPWDVGQHGWQTGNFLAPMSEWNDRYRDSVRTFWLADQAALTGGHSGHDLRDLATRLAGSADLFGHNGVPGGRGPTASINFVTAHDGFTLADLVAYDHKHNEANGEDNRDGTDNNRSWNHGVEGASTDPGVLAARRRSMRNLFGTLVLSAGVPMIAAGDEIARTQQGNNNGYCIDGDLTWVDWDAAHTGEIPDFTATVTYLLDLRRSHEVLRPAHYRSHTRSGRPTLSWYDRTGQAMEPETWYDPSQRVLQMARVQPEGEGRNLLAIFNGEIEAAGIALPTAEDGRYELVWDSEWAAPDHPSRGAVAGAGSQVTLAPMSLRVYLSS
>NZ_CP045920.1|WP_153877598.1|1112815_1113616_+|electron-transfer-flavoprotein-subunit-beta
MRIVVCVKHVPDLASARGFDDDRRTRRTAADSTLNEVDENAIEAALQVPGENEVIALTTGPAIAVDAVRRALQMGVDSAVHVQDDALAGLDAPATARVLAAAIAHLARPGAPIDLVLAGMTALDGLGSVVPTLVGAELGWGVLAGAQDLTVTDGPDGRLATISRDLDGAAERVRAALPAVVSVSDAINSPRLPKTKDILAARSAPVAAVALADLGLADGAASSRTRVTRAEPAPERPEPVIVHDTGGGGRALADYLIRNDLLGDAR
>NZ_CP045920.1|WP_153877599.1|1113612_1114608_+|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein
MTAPAVLVHVAHAGDHLADSTLEALTLARGLGEPIAVATSPPSPRALDQLATAGIDRVIVAGLDPDRALLAPAVGQVLARAVEHVGGGAGASVLIPASFFGKEVAAHTAHLLGAGLLIDVADVRRTPTGLAGGKRAFAGSWVCDCETTTPLAVVTIRPNAVAARAAERPGTPVLESLAVEVDLPAGLEVIERTVHSGSGRPDLAEATHVVAGGRGTYGDFAPVEELADALGGAVGTTRDCVEEGWISHDLQIGQTGVTIAPRVYIGAGISGAPHHHGGMQASSVVIAVNIDEEAPLVQICDFAVIGDAGSVLSEAAEVIRAHRYAEPPTGI
>NZ_CP045920.1|WP_153877600.1|1114617_1115808_+|aminotransferase-class-V-fold-PLP-dependent-enzyme
MGAYLDHAATAPVLPEAADAFARVARELGNPSAVHGYGRTTRRIVEESREEIAALLGAEAAEVILTSGGTEADNLAVIGAWQACAAGTADTAVPPGLIVSAIEHPAVLESAEWLASDRGARLHIAPVTTAGTVDLDALAGLLARPESERGRIAVCSIMWANNETGAIQPLPAVVELAGAHGIAVHSDAVQAAGRVPIDFAASGLAALSISGHKFGAPVGVGALLARRDFDMRSHQHGGGQERGVRSGTVNAAGARALAVALAAAVHDLSTEADRLAGLRDRLEAGIRAIAPDVRVWAGEAERLPGHLLVSVPGTRSEPVIFALDMAGVAASAGSACHAGVVGASPVVLAAGGTEEEARSALRFTLGRTSTAADIDAALAVLPDALGRARAVLEGIR
>NZ_CP045920.1|WP_153877601.1|1115804_1116911_+|tRNA-2-thiouridine(34)-synthase-MnmA
MKVLAALSGGVDSAVAAARAVDAGHEVVGVHMALSRSRAQHRTGSRGCCSIEDASDARRAADVLGIPYYVWDLSEEFEETVVADFVSEYEAGRTPNPCVRCNEHIKFAALLDRGLALGFDAVATGHYARIVPGPDGPQLHRSNDSAKDQSYVLAVMGPERLARSLFPLGNVTSKEEVRAEAAARGLSVSAKPDSYDICFVADGDTRGFLRDRLGSRAGEIVDTGGVVLGEHDGFFGYTVGQRKGLGIGRPADDGAPRYVVATEPASNRVIVGPAALLSVDELRANDVVWLAGDIDPGDGLDGLTVQVRAHGTPVGARVRRVEGELVARLEEPIRGIANGQSLVVYADTRVLGQGSISASARLGDRLAR
>NZ_CP045920.1|WP_153877602.1|1117003_1117948_+|hypothetical-protein
MRRTDRRIACLSALLAGVLAVAGCAGEVTVPVDAASSAPPASAGPSDPAGEPGAGGTGGAPPTPSTPTGPTGSTGPTGSTGPDASATPNPPRIDPPAPVETAPVETGPVETGPGETAPPPADPDGDDSGPRPPGPSTPSTPSTPSERPTADPTRPAPQEPEPTSPAPEPAPAPPIEGWAALISQSRTGEAPAAFRARERYVSCGDLVRAHGQELLPPDVVACLDAGADGEGAEAAVAVPSDTGAALVWFVRVGPAGSEVFVDATRDSRRGEWTHTTCDPDVSIVALACAEPGPIPGPSADETRPAPGEGETMAA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP045920_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045920_4

1934013-1934131

Orphan

Consensus_repeat	Method
CCTGCGGGGCGCCATACGGCTGGCCCTGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045920_4

>merge|NZ_CP045920|4|1934013-1934131|CRISPRCasFinder
CCTGCGGGGCGCCATACGGCTGGCCCTGCGGCTGATCCTGCGGGGCGCCATACGGCTGGCCCTGCTGATAGGGCTGACCCTGCGGCTGGCCCTGCGGGGCGCCATACGGCTGACCCTGC

>NZ_CP045920|4|3|1934013-1934131|CRISPRCasFinder
CCTGCGGGGCGCCATACGGCTGGCCCTGC	GGCTGATCCTGCGGGGCGCCATACGGCTGGCCCTGCTGATAGGGCTGACCCTGCGGCTGGC
CCTGCGGGGCGCCATACGGCTGACCCTGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045920.1\|WP_152818582.1\|1927887_1929024_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|376820
NZ_CP045920.1\|WP_152818580.1\|1931040_1932057_-\|heat-inducible-transcriptional-repressor-HrcA	unknown	unknown	gnl\|CDD\|234621
NZ_CP045920.1\|WP_153878081.1\|1923696_1925226_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|224423
NZ_CP045920.1\|WP_153878086.1\|1934534_1935746_-\|coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|180172
NZ_CP045920.1\|WP_153878084.1\|1932216_1933068_+\|DUF3097-family-protein	unknown	unknown	gnl\|CDD\|378628
NZ_CP045920.1\|WP_153879201.1\|1926119_1927418_-\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|224173
NZ_CP045920.1\|WP_153878091.1\|1940997_1943151_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|274357
NZ_CP045920.1\|WP_153878090.1\|1939341_1940847_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|273327
NZ_CP045920.1\|WP_153878080.1\|1921851_1923645_-\|FHA-domain-containing-protein	unknown	unknown	gnl\|CDD\|236138
NZ_CP045920.1\|WP_153878089.1\|1938510_1939284_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377640
NZ_CP045920.1\|WP_153878094.1\|1945023_1945473_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377126
NZ_CP045920.1\|WP_152818583.1\|1927438_1927891_-\|rRNA-maturation-RNase-YbeY	unknown	unknown	gnl\|CDD\|234575
NZ_CP045920.1\|WP_153878082.1\|1929102_1929891_-\|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	unknown	unknown	gnl\|CDD\|236959
NZ_CP045920.1\|WP_153878083.1\|1929887_1930994_-\|molecular-chaperone-DnaJ	unknown	unknown	gnl\|CDD\|237654
NZ_CP045920.1\|WP_153878095.1\|1945497_1945779_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377126
NZ_CP045920.1\|WP_153878092.1\|1943266_1943989_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045920.1\|WP_153878088.1\|1937949_1938210_+\|30S-ribosomal-protein-S20	unknown	unknown	gnl\|CDD\|178943
NZ_CP045920.1\|WP_153878087.1\|1935742_1937626_-\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
NZ_CP045920.1\|WP_153878093.1\|1944005_1945019_-\|DNA-polymerase-III-subunit-delta	unknown	unknown	gnl\|CDD\|236130
NZ_CP045920.1\|WP_152818584.1\|1925227_1926130_-\|GTPase-Era	unknown	unknown	gnl\|CDD\|234624

Protein	Function_ID	Function_description	E-value
NZ_CP045920.1\|WP_152818582.1\|1927887_1929024_-\|AAA-family-ATPase	gnl\|CDD\|376820	pfam02562, PhoH, PhoH-like protein. PhoH is a cytoplasmic protein and predicted ATPase that is induced by phosphate starvation.	5.49076e-137
NZ_CP045920.1\|WP_152818580.1\|1931040_1932057_-\|heat-inducible-transcriptional-repressor-HrcA	gnl\|CDD\|234621	PRK00082, hrcA, heat-inducible transcription repressor; Provisional.	1.26445e-135
NZ_CP045920.1\|WP_153878081.1\|1923696_1925226_-\|alpha/beta-hydrolase	gnl\|CDD\|224423	COG1506, DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism].	5.94234e-09
NZ_CP045920.1\|WP_153878086.1\|1934534_1935746_-\|coproporphyrinogen-III-oxidase	gnl\|CDD\|180172	PRK05628, PRK05628, coproporphyrinogen III oxidase; Validated.	0
NZ_CP045920.1\|WP_153878084.1\|1932216_1933068_+\|DUF3097-family-protein	gnl\|CDD\|378628	pfam11296, DUF3097, Protein of unknown function (DUF3097). This family of proteins with unknown function appears to be restricted to Actinobacteria.	2.99537e-152
NZ_CP045920.1\|WP_153879201.1\|1926119_1927418_-\|CBS-domain-containing-protein	gnl\|CDD\|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	1.95054e-89
NZ_CP045920.1\|WP_153878091.1\|1940997_1943151_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	2.66254e-27
NZ_CP045920.1\|WP_153878090.1\|1939341_1940847_-\|MFS-transporter	gnl\|CDD\|273327	TIGR00895, transport_protein, benzoate transport. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	8.57223e-65
NZ_CP045920.1\|WP_153878080.1\|1921851_1923645_-\|FHA-domain-containing-protein	gnl\|CDD\|236138	PRK07994, PRK07994, DNA polymerase III subunits gamma and tau; Validated.	1.97444e-15
NZ_CP045920.1\|WP_153878089.1\|1938510_1939284_-\|hypothetical-protein	gnl\|CDD\|377640	pfam06271, RDD, RDD family. This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N-terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown. However this region may be involved in transport of an as yet unknown set of ligands (Bateman A pers. obs.).	8.25481e-27
NZ_CP045920.1\|WP_153878094.1\|1945023_1945473_-\|hypothetical-protein	gnl\|CDD\|377126	pfam03772, Competence, Competence protein. Members of this family are integral membrane proteins with 6 predicted transmembrane helices. Some members of this family have been shown to be essential for bacterial competence in uptake of extracellular DNA. These proteins may transport DNA across the cell membrane. These proteins contain a highly conserved motif in the amino terminal transmembrane region that has two histidines that may form a metal binding site.	1.77304e-07
NZ_CP045920.1\|WP_152818583.1\|1927438_1927891_-\|rRNA-maturation-RNase-YbeY	gnl\|CDD\|234575	PRK00016, PRK00016, metal-binding heat shock protein; Provisional.	1.47557e-58
NZ_CP045920.1\|WP_153878082.1\|1929102_1929891_-\|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	gnl\|CDD\|236959	PRK11713, PRK11713, 16S ribosomal RNA methyltransferase RsmE; Provisional.	4.28392e-62
NZ_CP045920.1\|WP_153878083.1\|1929887_1930994_-\|molecular-chaperone-DnaJ	gnl\|CDD\|237654	PRK14278, PRK14278, chaperone protein DnaJ; Provisional.	9.09907e-175
NZ_CP045920.1\|WP_153878095.1\|1945497_1945779_-\|hypothetical-protein	gnl\|CDD\|377126	pfam03772, Competence, Competence protein. Members of this family are integral membrane proteins with 6 predicted transmembrane helices. Some members of this family have been shown to be essential for bacterial competence in uptake of extracellular DNA. These proteins may transport DNA across the cell membrane. These proteins contain a highly conserved motif in the amino terminal transmembrane region that has two histidines that may form a metal binding site.	4.45161e-06
NZ_CP045920.1\|WP_153878088.1\|1937949_1938210_+\|30S-ribosomal-protein-S20	gnl\|CDD\|178943	PRK00239, rpsT, 30S ribosomal protein S20; Reviewed.	1.7786e-25
NZ_CP045920.1\|WP_153878087.1\|1935742_1937626_-\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NZ_CP045920.1\|WP_153878093.1\|1944005_1945019_-\|DNA-polymerase-III-subunit-delta	gnl\|CDD\|236130	PRK07914, PRK07914, hypothetical protein; Reviewed.	2.66697e-51
NZ_CP045920.1\|WP_152818584.1\|1925227_1926130_-\|GTPase-Era	gnl\|CDD\|234624	PRK00089, era, GTPase Era; Reviewed.	9.37591e-156

>NZ_CP045920.1|WP_153878084.1|1932216_1933068_+|DUF3097-family-protein
MTDRYGRDVLSRDPHHSKRPTTTDIPARTGLVVEDVTSGWVGAVVRVEKSGGAHVVVLEDRRGVTRTFPLGAGFWVEGRPVRLVPPVRPAAPAAPARTASGSVAVRGARARTARASRIWVEGRHDAELIEKVWGEDLRIEGVVVEMLDGVDHLAAELAAFSPGPRRRVGVLVDHLVPGSKESRIAAEVCARHPGVLVLGHPYVDVWQAVRPERVGLAAWPDIPRGIDIKVGSLRALGWEAGSQADIARGWKRILGRVRDFRDLEPSLLGRVEELVDFVTAVPE
>NZ_CP045920.1|WP_152818580.1|1931040_1932057_-|heat-inducible-transcriptional-repressor-HrcA
MTRERHIDVLRAIVQDYVHTREPVGSRSLVERHNLGVSPATIRNDMALLEEAGLITQPHTSAGRIPTDAGYRLFVDRLDEIKPLSAAERRAIGALMQGAVDLDDALERTVRLLAQLTQQVAVVRYPSLRRSALRHVELLPASSTRILMVIISDNGQVEQRTIEADEPLTEELLAELRARINAAGAGRRMPELATALHQIAASFPAQDQPTAAGVVTAVLEVISDEIEERIVMAGTAHLARTNVDFSRTISPVLEALEEQVVMLRLLSDMASEPSIAVRIGSETHDEALLETSVVAGRYSSTDAGVLGQLGVIGPTRMDYPTTMAAVHAVARYLSKTLS
>NZ_CP045920.1|WP_153878083.1|1929887_1930994_-|molecular-chaperone-DnaJ
MSDYYEILGVSREATTEEIKRAYRKLARQHHPDIAGPESEERFKQITEAHEVLSNPEKRQMYDVGGSQGGSGAGFGFSDMFDFFAAAAGGATQRGPVSRSRRGQDALVRVSISLADATFGVTKELEVDTAVMCEACHGTCTRPGTSPTTCPTCHGRGSVQRVARSFFGNIMTNAPCSDCGGFGTIISEPCAECSGEGRVRARRTISVNIPAGVDTGTRIKLTGKAEVGPGGGPAGDLYVEVREQRHETFTRRGDDLHCTVELPVTAAALGTVVTLETLDGIHDVDIAPGSQPGQVLTLKGLGVGHLNRTGRGDLNVHLEVEVPTRLSDEEEELLRQLAVLRGEERPEARVAATKNSVFQRLKDTFASR
>NZ_CP045920.1|WP_153878082.1|1929102_1929891_-|16S-rRNA-(uracil(1498)-N(3))-methyltransferase
MTDPVFFAADLPAAARVGDTFELTGPEARHAVAVRRIRVGEAIEIVDGAGTRLRGRATAVGANPPSLTLGVEDRVLEPAPSPELILVQALGKGGRDEAAIEAATELGVDAVVAWQAERSVARWDGPKVAKGVHRWESILVAAAKQSRRARFPRMLGFAAGPGILGVGGPLGPAIAAGARILVLHESAEAPLTAMALGSGRDAGPADRPVVVVVGPEGGLSEAELARWSGAGGTATLLGPHVLRTSTAGPAALTVLNARLGRW
>NZ_CP045920.1|WP_152818582.1|1927887_1929024_-|AAA-family-ATPase
MSASTHSPPEPSSPDEATHQVVIPDSVPMVALLGRRDEVIRAVESGFRGLDVHVRGNVVTLTGPAGQVDLAHRLFDELSQIAAADQPLSADAVERAIGILTATSDKPAEVLTMNILSGRGRTIRPKTVGQKDYVEAIDRNTVVFGIGPAGTGKTYLAMAKAVKALQSKEVNRIVLTRPAVEAGERLGFLPGSLNDKIDPYLRPLYDALHDMVDPESIPRLMAAGTIEVAPLAYMRGRTLNDAFIILDEAQNTSPEQMKMFLTRLGFGSRIVVTGDVTQVDLPVGTHSGLRVVQEILAGIDDIAFCRLTSADVVRHRLVGDIIDAYTGYDERSDGPEDRRPVRRGHPRRAPGSSVDSGDSGHSGYSGRSAGRADQEGPA
>NZ_CP045920.1|WP_152818583.1|1927438_1927891_-|rRNA-maturation-RNase-YbeY
MSVDIMNESDTPVDEVEFVALARHVLDAMFVHPQAELEIRFVTTDVMTELHEQWLDEPGPTDVMSFPIDELRPGTEAEPSDEGMLGAVVLCPEVAAAQAREAGHSAVEEMLLLTTHGILHLLGYDHAEAAEEKEMFDLQRQLLLTFLAGA
>NZ_CP045920.1|WP_153879201.1|1926119_1927418_-|CBS-domain-containing-protein
MAAPIPLLVAVAVVAIAAGAILSAGEEAGRSITRAAAHEAAIEGRRRAGALRAIAAIAADSTGPVRATAYLRLVTEMTGAVCVTLVYAVVFERWWVALLCAVATVALLNIVVVGISPRTLGRRRPVAVLALVGPFMHGAHRIMAPFVARVGPSRASGPTWETEGELQDMVDRVAESAHIEDDEREMLQSVFELSRTMVREVMVPRTDMVTVRPDVTLTKALSLFTRSGFSRIPVAGESLDDLRGVLYLKDLLRKLTSAPERSEHRIERVMREAVFVPETKVVDDMLAQMRASGVHIAIAFDEYGGVAGLVTIEDVLEELVGDLTDEHDQSEPQVEPDGDGYRVPARLPLDELGELFDLEIDDPEVDSTGGLLTKALGRVPILGSVALDHGLRFEVVEASGRRRRVSTILVTRAQENPPAEPTTHPEETPHGP
>NZ_CP045920.1|WP_152818584.1|1925227_1926130_-|GTPase-Era
MARDATFRSGFACLVGRPNAGKSTLTNALVGEKVAITSTRPQTTRRALRGIVNRPDGQLVLVDTPGLHRPRTLLGERLNDLVADTLSEVDVIGFCLPADQPIGPGDRFIAGQLASRRTPVVAIATKIDAVGPERVVHHLTQIGDLGDWAEIVPVSATRGTQVDLLAEILVRYLPTGPVLYPDGELSDEDPEVTIAELVREAALEGVRDELPHSLAVLVEEIVERPDRRDHLTDVRVNLYVERPSQKAIIIGTRGSRLRQVGTQARQGIQRLLGVPVYLDLHVKVAKDWQKDPKQLRRLGF
>NZ_CP045920.1|WP_153878081.1|1923696_1925226_-|alpha/beta-hydrolase
MGLRGVLGTERTVELRTGWQRFWPVALTSLVVATILGVSGALAGPRWAPTEMHRTIIPTTADVRIGGTEQSPVGTYTVRVEPIRIDLGEVTVDGLLFLPEGAPAGPGVVFMHGAGTGEPEAFAPHGQALASAGIRVLVPAKRLDDYSTRERNYPSMAQDYLVSWRYLRERVPGVDPDRVGFYAESEGAWIAPIAAADEPDVAFLMLISAPVVPPREQAAFATANYLRNTHVPRGVFRAIPRALGAQIPGGGFEYVDFDVLPYLRQVDVPVLMAYGTDDASMPIVQGALIVIDTLAAHGNDAVTVRYFDGADHGLMIDEQLAPGFTTVLSSWTLGLPATASAPPQIAGDRPEQEYRAAAVPSPAWFASGDMLVWSIIGSFLLVVAGLGLGAVSLVRRRSPAAAVGRLAVAAGLAALAVVTTFVAYIAQIATLAMNYHLDDTVVIGGWILVQLLGIFAVVVGVVSVRAAMHARRAGTYFTVTDKVSWWATHVGSLALLLVAAYWGVFPAVG
>NZ_CP045920.1|WP_153878080.1|1921851_1923645_-|FHA-domain-containing-protein
MRYSYGPGDWLTLAHDGAGALVHPGIPPAVVERVWGAMVAAAPMPAWVRELEGTAGPYALVHMGVDGVRVLLRGSVSALIGGRRLSGRDGAPWAEHIGLGVYEAHVWVEGASVERTYPLAGGVVFAHTLSVRDPGGAQGTVRVAGATIAQILGVQPELAPVPPVPLVTGEQPPPPAGTSQTDTAGPVGTAGPVGQLGQAGPPDHGGRTGSAAVLPPEPSPGEGALDDISDIEELERTILGRPFARGPVPGGAPEPAPPAQSLPPMPPVPPEPPAQSLPPEPPAQSLPPESPAQSLPAAPPAQSLPADPPEPPAQSLPPEPPAPPAAAAPPEPPAPPAASVPPEASAPPAASVPPEASAPPAAAAPPEPSVPPAPPVPPAPSAPSAPEHSLPAGIIDSVPRTRPGLARPQPAGAPVDDATIIPHRYGPDGDAPAPSAGSAVDAAPESTILSSVPPAQAARLASAQAAQGVQGAQGAQAAENTAATRAILRVSTGQVCHLSTPVLVGRSPDAGASTVAGAAPQLLAVPSPNLDISRNHAEIRVEGEHVLVTDLRSTNGTVVNTPGAGPRRLRAGESVQVGSGTTIDLGDGVTMIVDQRA
>NZ_CP045920.1|WP_153878086.1|1934534_1935746_-|coproporphyrinogen-III-oxidase
MTAAPERSDRFGVYVHVPFCAVRCGYCDFNTYTATELGGGASRDEYAETALGEMRLAAAELVRRGRRVDGVTTVFFGGGTPTLLPVGDLRLLLAGIDETWGLAPGAEVTTEANPDSVGPAELADLAAAGFTRVSFGMQSAVPAVLATLDRTHDPERLPLVVEWARAAGLAVSVDLIYGAPGESVEQWRTSVEAAIALEPDHISAYALTIEPGTKMAAQVRRGQLPMPDPDDQATKYELADEAFAAAGYGWYEISNWARPDGTGGSGGSGGLPADTAADHRCRHNLAYWRNEEWWGIGPGAHSHLGDTRFWNVKHPRPYAQRIREGRLPIAESETLDATQQEDERILLGIRLVEGLGVGPGLEDRLPALAEQGLIDGAAAAGGVARLTRRGRLLADAVVGRLVA
>NZ_CP045920.1|WP_153878087.1|1935742_1937626_-|elongation-factor-4
MPPIPSAHAAQQIVPAATVPEQLRNFCIIAHIDHGKSTLADRMLQLTGVVDQRQMRAQYLDRMDIERERGITIKSQAVRMPWARLDADGTERAYALNMIDTPGHVDFSYEVSRSLAACEGALLLVDAAQGIEAQTLANLYMALENDLTIIPVLNKIDLPAAQPEKCAEELAGLIGVEPEECLLVSGKTGVGVEELLDRIVEDVPAPQGNPDAPSRAMIFDSVYDSYRGVVTYVRVIDGTLSPREKVVMMSTKTNHELLEIGVSAPEPRPTKGLSVGEVGYLITGVKDVRLSRVGDTVTNAAKPAADVLAGYRDPQPMVFSGLYPIDGSDYPVLRDALDKLRLNDAALTYEPETSVALGFGFRCGFLGLLHLEIVRERLEREFNLELISTAPNVVYDVTMEDGTEVVVTNPSEFPAGKLASVSEPMVKATILTPSDFVGQVMELCQGRRGVMQGMDYLSSDRVELRYHLPLAEIIFDFFDQLKSRTRGYASLDYAESGHAEADLVKVDILLQGEQVDAFSAIVHKDKAYAYGVDMTTKLRGLIPRQQFEVPIQAAIGSRIIARETIRAIRKDVLAKCYGGDISRKRKLLEKQKEGKKRMKNIGTVEVPQEAFIAALTSDGSGSDSKKS
>NZ_CP045920.1|WP_153878088.1|1937949_1938210_+|30S-ribosomal-protein-S20
MANIKSQIKRNRTNEKARLRNKAVKSELKTHVRTVRSAITAGDKDAAETALQEAGRKLDKAVSKGVIHKNQAANRKSALAKKVAKL
>NZ_CP045920.1|WP_153878089.1|1938510_1939284_-|hypothetical-protein
MSCCGRRPPGHSPDENQRRKETTMTENPQQPQQPGYGQQPPPPPQQAYGQQVPPQQQPYNQPGYNQQPGYAQQPGQFPQAAPPPPQPTGPGRPGELMPRFLARLVDGILLGIVYGILYAIIMAMLVPNTFDAILSGQSVAGRILLANAILAVLGAVIMLGYYAFLESSRGQTVGKMITKLRVHGPTSEKPTMSEAVKRNIWMAAGIAGIIPVVGSALGGIASLVAVIMIAVGINADTVGRQAWHDKFAGGTRVVTTE
>NZ_CP045920.1|WP_153878090.1|1939341_1940847_-|MFS-transporter
MGRTWAGLDRPRTSPGGCVPVTTETTQTPTRLERLGRLPFTRLHRRLLTGSGAGWAMDAMDVGLISFVMAALKSEWQLTTEQVSWLGSIGFVGMALGASLGGLLADRIGRRNVFALTLLIYGIATGASALAGSLALLLIFRFVVGLGLGAELPVASTLVSEFAPPRIRGRLVVILEAFWAVGWLAAALIGYFVVAAGDSGWRWGLAIGAVPALWAVYVRRNLPESVHFLESRGRVDEAEAIVRQFEQSPPLRRSGEAGPGDSAEAVPVATAAPTTVSAAPAAPAEPAEPAAAVPVSARQRLALLFSAEHRRRTIGLWGVWFLVNFAYYGAFIWLPTLLIDRGISISQSFGYTLIITAAQLPGYAVAAWLIEAWGRRATLVTFLGGSAVSAFLFALAAINAAPGTETLIVLSGCLLSFFALGAWGAVYAVGPEMYPTGIRGTGTGWAAGFGRIASIVAPLSVVWIQDAGGSWTTVFIVFAIAYLLSAGCALLLSERRGRILD
>NZ_CP045920.1|WP_153878091.1|1940997_1943151_+|sigma-70-family-RNA-polymerase-sigma-factor
MIASSSKPSGPKSSTGGGTWGRPRERSGRSHMAAMNRMAGDQDDPVAADTVRAGFLDSYDLLYRNHYDSAVAQARRVCGSGIDPDDVAQDAFLQVFRALKRGAGPTREFRPYLLATVRNTAADLQRNIRETPTAEIESAQPATPSHRTDEEIEFATVGAAFRQLPERWQEVLWLTEVEGYTPRLLAKHFALRPNAVAALSSRAREGLRSAWLGAHLSGRELSGDCARLAPYLADHERGTLSATRAALVDAHLEDCEDCRRATGRLAALSQRMPALLLPALLLAAKSWTVPTVLVAGGTAGGLTGALAGSLGPLGWVKGALRAARTMSTGQALGAGGVLVVTTAVGAAAWQAATPDDPAASPPAAVSSDPQAPQAPSGATATDAATQETTAAGTAPNTGDAEEPDQGEDPSSISVSGPAGGTSIPVLLPPATPPRVITPGPGPGESGPAPSADSSPPPTPAPEPAPEPAPEPTPTPTPDPEPTPTPDPSPDSTPDPEPTPDPTPDPEPTPDPTPDPEPTPDPEPTPDPEPTPDPEPTPDPGLPPAPVIDDVVAEQYVVHPLAGTAEPGGRITVTDTAGAVVGSTVAADDGTWSVVPSITTAGEHTFRVTAARDGAVSEPATIGPVDYLAPTAEDVEFLPGVLPWLVGVRIDLPAGIDRPEHLVFTPVDGSAPSTLTDVLGDVWNVYVGVLPPGDYTVDLTYTAGELRGIPTRIELTSP
>NZ_CP045920.1|WP_153878092.1|1943266_1943989_+|hypothetical-protein
MLLAPLHVLPRPAREAHPKVRSFVVSSAWSATGSTLLQGLLARGGPAYGVDLTSLRTPGRVGDQARRSFIDFLDRMSVAAVLPSTPQDHETLAELARTEHPERFITASPDTLARMRDRSLLAEAFAHAGQAAPDGSHPDVAPYLAVTYRPTAHAGATHVWLYRWADGGHELIVDADLRDELRAPLVDLVAALGVTGVATFGLTLTNDATALVLSAHPGFTQMSAHCPEVSEYLVSRFTEL
>NZ_CP045920.1|WP_153878093.1|1944005_1945019_-|DNA-polymerase-III-subunit-delta
MPPRARSAALSPQDLDSIPLAPIVLVKGGEGYFVDRVTEHLTRLATELDPGVEVVRVEAGAYEPRMLDTWLSPSLFDERRHIVVGGVDAATDAFITDLLAYVDGLGAALEDVSIVLRHERGTRGKKLLDRIAKAGFPVVACDPLKKDADKAAFVSQYFASERRAIAKDAVRGLVEATGSDLRELAAACRQLCDDVTGRITADVVLRYYGGRVEATGFRVADSAIGGDGAAAVTLVRHALATGMDPVPLVAVLGMKLRTLAGVSAMRSRGLTAGDLKLAPWQVDRARRDLNGWTPEGLARAITAVADADAAVKGESRDRGYAVERAVLDIAAARGRRG
>NZ_CP045920.1|WP_153878094.1|1945023_1945473_-|hypothetical-protein
MSVSATAGLVVWTEPLAARLARFVPTGVARLVALPIAAQCWCAPILVLLSPTLPTYAVPANLLAAVAMPPATLLGLAATLGGVLWPAFGALACLAATWCAGWVAAIATAFASLPGALLPWPGGPAGAVGLELIVAAAGAWAHRRLRVAG
>NZ_CP045920.1|WP_153878095.1|1945497_1945779_-|hypothetical-protein
MQHPPREITLSGGHVAVVVGLVLLLLARAPVLVRAGCGLVVLAGMVVLVLATASVVRSAGMGVVMLAALGLRRPRLALPALAGAVIVLLAADP

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP045920_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045920_5

2183352-2183435

Orphan

Consensus_repeat	Method
GATGAGGGTGGCCCCAACCCCCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045920_5

>merge|NZ_CP045920|5|2183352-2183435|CRISPRCasFinder
GATGAGGGTGGCCCCAACCCCCTGTGAGAGGGTCAGGACAACCCTCATGATGGCGCCCGCCGATGAGGGTGGCCCCAACCCCCT

>NZ_CP045920|5|4|2183352-2183435|CRISPRCasFinder
GATGAGGGTGGCCCCAACCCCCT	GTGAGAGGGTCAGGACAACCCTCATGATGGCGCCCGCC
GATGAGGGTGGCCCCAACCCCCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045920.1\|WP_153878229.1\|2171030_2172341_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223104
NZ_CP045920.1\|WP_153879217.1\|2175920_2176994_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238645
NZ_CP045920.1\|WP_152909845.1\|2188830_2189421_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|239737
NZ_CP045920.1\|WP_153878243.1\|2191231_2191645_-\|glyoxalase	unknown	unknown	gnl\|CDD\|319943
NZ_CP045920.1\|WP_153878233.1\|2178155_2179178_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|226361
NZ_CP045920.1\|WP_153878238.1\|2184377_2185232_-\|oxidoreductase	unknown	unknown	gnl\|CDD\|381314
NZ_CP045920.1\|WP_153878232.1\|2177034_2178114_-\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|270307
NZ_CP045920.1\|WP_153878244.1\|2191641_2192523_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|378964
NZ_CP045920.1\|WP_153878240.1\|2186322_2187927_-\|sodium:proton-antiporter	unknown	unknown	gnl\|CDD\|129911
NZ_CP045920.1\|WP_152909890.1\|2179174_2179918_-\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|224098
NZ_CP045920.1\|WP_153878234.1\|2181024_2182029_+\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525
NZ_CP045920.1\|WP_153878231.1\|2174462_2175848_+\|glucose-6-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|237233
NZ_CP045920.1\|WP_153878242.1\|2189428_2190133_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378065
NZ_CP045920.1\|WP_153878230.1\|2172465_2174466_+\|glycoside-hydrolase-family-15-protein	unknown	unknown	gnl\|CDD\|225922
NZ_CP045920.1\|WP_153878241.1\|2188039_2188696_-\|HAD-IA-family-hydrolase	unknown	unknown	gnl\|CDD\|319825
NZ_CP045920.1\|WP_153878237.1\|2183499_2184261_-\|YggS-family-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|143483
NZ_CP045920.1\|WP_153879218.1\|2190129_2190459_-\|transcriptional-regulator	unknown	unknown	unknown
NZ_CP045920.1\|WP_153878235.1\|2182106_2182649_-\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP045920.1\|WP_152909834.1\|2179968_2180790_-\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|224097
NZ_CP045920.1\|WP_153878239.1\|2185313_2186243_-\|DUF808-family-protein	unknown	unknown	gnl\|CDD\|377542

Protein	Function_ID	Function_description	E-value
NZ_CP045920.1\|WP_153878229.1\|2171030_2172341_-\|hypothetical-protein	gnl\|CDD\|223104	COG0025, NhaP, NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism].	4.83699e-12
NZ_CP045920.1\|WP_153879217.1\|2175920_2176994_-\|hypothetical-protein	gnl\|CDD\|238645	cd01320, ADA, Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in the purine pathway. Low, as well as high levels of ADA activity have been linked to several diseases.	2.7712e-72
NZ_CP045920.1\|WP_152909845.1\|2188830_2189421_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|239737	cd03768, SR_ResInv, Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1.	8.31531e-41
NZ_CP045920.1\|WP_153878243.1\|2191231_2191645_-\|glyoxalase	gnl\|CDD\|319943	cd08355, TioX_like, Micromonospora sp. TioX and similar proteins. Micromonospora sp. TioX is encoded by a gene of the thiocoraline biosynthetic gene cluster. Thiocoraline is a thiodepsipeptide with potent antitumor activity. TioX may be involved in thiocoraline resistance or secretion. TioX belongs to vicinal oxygen chelate (VOC) superfamily that is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	3.27371e-31
NZ_CP045920.1\|WP_153878233.1\|2178155_2179178_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|226361	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism].	1.63026e-139
NZ_CP045920.1\|WP_153878238.1\|2184377_2185232_-\|oxidoreductase	gnl\|CDD\|381314	cd19088, AKR_AKR13B1, AKR13B family of aldo-keto reductase (AKR). Xylella fastidiosa phenylacetaldehyde dehydrogenase is a founding member of aldo-keto reductase family 13 member B1 (AKR13B1). phenylacetaldehyde dehydrogenase (EC 1.2.1.39) catalyzes the NAD+-dependent oxidation of phenylactealdehyde to phenylacetic acid.	4.0154e-135
NZ_CP045920.1\|WP_153878232.1\|2177034_2178114_-\|extracellular-solute-binding-protein	gnl\|CDD\|270307	cd13589, PBP2_polyamine_RpCGA009, The periplasmic-binding component of an uncharacterized ABC transport system from Rhodopseudomonas palustris CGA009 and related proteins; contains the type 2 periplasmic-binding fold. This group represents the periplasmic binding domain that serves as the primary high-affinity receptor of an uncharacterized ABC-type polyamine transporter from Rhodopseudomonas palustris Cga009 and related proteins from other bacteria. Polyamine transport plays an essential role in the regulation of intracellular polyamine levels which are known to be elevated in rapidly proliferating cells and tumors. Natural polyamines are putrescine, spermindine, and spermine. They are polycations that play multiple roles in cell growth, survival and proliferation, and plant stress and disease resistance. They can interact with negatively charged molecules, such as nucleic acids, to modulate their functions. Members of this family belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.58487e-61
NZ_CP045920.1\|WP_153878240.1\|2186322_2187927_-\|sodium:proton-antiporter	gnl\|CDD\|129911	TIGR00831, Putative_Na+/H+_exchanger_Rv2287/MT2345/Mb2309., Na+/H+ antiporter, bacterial form. The Monovalent Cation:Proton Antiporter-1 (CPA1) Family (TC 2.A.36) The CPA1 family is a large family of proteins derived from Gram-positive and Gram-negative bacteria, blue green bacteria, yeast, plants and animals. Transporters from eukaryotes have been functionally characterized, and all of these catalyze Na+:H+ exchange. Their primary physiological functions may be in (1) cytoplasmic pH regulation, extruding the H+ generated during metabolism, and (2) salt tolerance (in plants), due to Na+ uptake into vacuoles. This model is specific for the bacterial members of this family. [Transport and binding proteins, Cations and iron carrying compounds].	5.38055e-46
NZ_CP045920.1\|WP_152909890.1\|2179174_2179918_-\|ABC-transporter-permease-subunit	gnl\|CDD\|224098	COG1177, PotC, ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism].	2.46701e-56
NZ_CP045920.1\|WP_153878234.1\|2181024_2182029_+\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	1.76339e-54
NZ_CP045920.1\|WP_153878231.1\|2174462_2175848_+\|glucose-6-phosphate-dehydrogenase	gnl\|CDD\|237233	PRK12853, PRK12853, glucose-6-phosphate dehydrogenase.	2.19707e-175
NZ_CP045920.1\|WP_153878242.1\|2189428_2190133_-\|hypothetical-protein	gnl\|CDD\|378065	pfam08843, AbiEii, Nucleotidyl transferase AbiEii toxin, Type IV TA system. This family was recently identified as belonging to the nucleotidyltransferase superfamily. AbiEii is the cognate toxin of the type IV toxin-antitoxin 'innate immunity' bacterial abortive infection (Abi) system that protects bacteria from the spread of a phage infection. The Abi system is activated upon infection with phage to abort the cell thus preventing the spread of phage through viral replication. There are some 20 or more Abis, and they are predominantly plasmid-encoded lactococcal systems. TA, toxin-antitoxin, systems on plasmids function by killing cells that lose the plasmid upon division. AbiE phage resistance systems function as novel Type IV TAs and are widespread in bacteria and archaea. The cognate antitoxin is pfam13338.	0.000201726
NZ_CP045920.1\|WP_153878230.1\|2172465_2174466_+\|glycoside-hydrolase-family-15-protein	gnl\|CDD\|225922	COG3387, SGA1, Glucoamylase and related glycosyl hydrolases [Carbohydrate transport and metabolism].	4.63743e-123
NZ_CP045920.1\|WP_153878241.1\|2188039_2188696_-\|HAD-IA-family-hydrolase	gnl\|CDD\|319825	cd07523, HAD_YsbA-like, uncharacterized family of the haloacid dehalogenase-like superfamily, similar to the uncharacterized Lactococcus lactis YsbA. The specific function of Lactococcus lactis YsbA is unknown. Members of this family belong to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	4.25283e-29
NZ_CP045920.1\|WP_153878237.1\|2183499_2184261_-\|YggS-family-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|143483	cd00635, PLPDE_III_YBL036c_like, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins. This family contains mostly uncharacterized proteins, widely distributed among eukaryotes, bacteria and archaea, that bear similarity to the yeast hypothetical protein YBL036c, which is homologous to a Pseudomonas aeruginosa gene that is co-transcribed with a known proline biosynthetic gene. YBL036c is a single domain monomeric protein with a typical TIM barrel fold. It binds the PLP cofactor and has been shown to exhibit amino acid racemase activity. The YBL036c structure is similar to the N-terminal domain of the fold type III PLP-dependent enzymes, bacterial alanine racemase and eukaryotic ornithine decarboxylase, which are two-domain dimeric proteins. The lack of a second domain in YBL036c may explain limited D- to L-alanine racemase or non-specific racemase activity.	2.58324e-108
NZ_CP045920.1\|WP_153878244.1\|2191641_2192523_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|378964	pfam12833, HTH_18, Helix-turn-helix domain.	5.68177e-15
NZ_CP045920.1\|WP_153878235.1\|2182106_2182649_-\|TetR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	6.16718e-06
NZ_CP045920.1\|WP_152909834.1\|2179968_2180790_-\|ABC-transporter-permease-subunit	gnl\|CDD\|224097	COG1176, PotB, ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism].	1.21083e-61
NZ_CP045920.1\|WP_153878239.1\|2185313_2186243_-\|DUF808-family-protein	gnl\|CDD\|377542	pfam05661, DUF808, Protein of unknown function (DUF808). This family consists of several bacterial proteins of unknown function.	5.63044e-116

>NZ_CP045920.1|WP_153878235.1|2182106_2182649_-|TetR-family-transcriptional-regulator
MSEARDRLLSTVVDEIAEHGMAGRSLRELAGAVGTSHRMLLYHFGSREGLVAAISAEVDERERGLLAGLVAGADGPADLVRGLWVRVSSPQWRPYVRLYFESLSSSARYPSAEDDLTAPWLEAGARAAEAGGWTIGADDLRLAVAVVRGLLVDVLATGETAAATAALERFLRLWDPPSAG
>NZ_CP045920.1|WP_153878234.1|2181024_2182029_+|LacI-family-DNA-binding-transcriptional-regulator
MATLNDVAIRAGVSKATASRALNHPALVAPATAERVLVAARELDFVPNRLARQLALGRTGIVSMLFPTLSNAFFTPIIAGAQDRAEELGLYLTVTAQPLAAAAELSHLADLARQVDGFVVVAPRGDDALVTRAMALRPSVLVDREIDGHTSVVADTASAFAALMRGLAAAGHRRVVFIGGPDRSWQNVQRTRAIEHAARTGGVDITVLGPAEPNFLVGQSLAQEVRASGATAVLPYAADLGLGVLFELVRSGHSTLGPASSSPGLIEVVGVPDSPAVAVDGHALGREALDRLHERLAADPHGSPPASTQQRLPVPISQAGPHPTHFPSPAHSPG
>NZ_CP045920.1|WP_152909834.1|2179968_2180790_-|ABC-transporter-permease-subunit
MRGRKYSFLILPGLLVLLVGFLIPSVAMLLAPPGLGPADVFARLGQMLTDSYDLEIIGRTVGLGLITTVICVVLGFPIAYLLARTAGRWAGILLALAIFPLLLSSVVRTFGWLVLLGSQGAIGQLLTGLGLVDEAPQLLYTPLAIVLGLTQLFLPLAIITCYSSVAQVDAGLDDAARGLGATRTRTFWSVVFPLSLPGVVVAATLVFAGAITAYTTPYLLGGSRQRMLSTQLFTYSSTTLDWAAASATAIIMTILVFAVSGASALLARKGAVS
>NZ_CP045920.1|WP_152909890.1|2179174_2179918_-|ABC-transporter-permease-subunit
MIVPLLFVVVTAFSAERTLRFPPSSYSLTWFGEALSYTPFMTSLANSLGLALIAVVIALALGVPVTLAIHRGNLPGKSLLEGLFLSPLIVPELVVGLALYQQLMVRFGLDNFQTLLFGHTVLMFPYAVRVTGASLALMDPAVEDAARGLGASPVRTFFSVVLPQLRPGLFSAALLSFIASFNNVPLSLLLQSREFRTLPVVMLDYVQQNYTPIVAAISVLILAATVLIAVITERTVGFTRVFGGING
>NZ_CP045920.1|WP_153878233.1|2178155_2179178_-|ATP-binding-cassette-domain-containing-protein
MTAAEFQNLTKSFGDFTAVDDMSLTIPQGRLTTLLGPSGCGKTTSLRMLAGYLSPDSGRILIHGTDATTTPPEKRNLGMVFQSYALFPHMTVAENVAFGLKVRRVPAEARRRKALESLELVGLAHQAGKKPKQLSGGQQQRVALARAIAIEPELLLLDEPLSNLDARLRIQMRAELRRIQSETGLSVVLVTHDQDEALEMSDEMVLMKDGRIQQQGAPQDVFPNPANRFVAEFLGYENFLTLAGGRRATVRPEHLRLTENTAGTADARHTADAATLTLTGHVRDIVYRGVDVLTTVTATDRSGDEVRLLVDSRATTVPDLRIGDAVSVHAPDRHVVTLSN
>NZ_CP045920.1|WP_153878232.1|2177034_2178114_-|extracellular-solute-binding-protein
MITQRQILGTGAAVLAATLTVAGCSDSGEQSGGDAGGSASIVVSTFPFGVEEFTQAVLDPFTEATGIEVEIDTGSNADRLSQLSLADGSNGVDVMLISDTYAGMGEEEGLFQPVTAADVPTMDEIAPFAVSEQYSGPAYSYQLNGTMYNTDELTAEEAASWDLYANADYAGRLALPDISVTAGQLMVSGVAASVGSGPYDVDAAFATLGEWAPNILQFYSSTTEMTNLLTQGEIVAGDALNGFATELVAAGEPIAWTAPAQGRYMATNRAMIPVGAENVEGATKFIDFLLGVEAQQASAEIVGDLPVNLGIEFPQEIIDVVGDIAQDPTGAGYETLDPREIVPNRDVWVERFAREVVGG
>NZ_CP045920.1|WP_153879217.1|2175920_2176994_-|hypothetical-protein
MPKVDLHCHLLGTVRAATFGELARRERLDLPESPEAIYAGINSRPPDPELYRSTRIPMPQGRSPDEPKTSYSLFQASEWVRAVVRTPEDLSRIAYEACADAFLGSGTRHLEFSFDMIPGHLAPIGYAGVVEAMADGIRRAEREFAMTARMLAAIDRSGSAQEALEWIRTVVEHPHEYVVGIGLDNLENSGPPERFAEAYALAGAAGLGRTAHTSEHVPAATNAVTCLDVLGCDRLDHGYFILEDDEVVARMRAEQVPFTVASTTSRRSWRPWRRASIAAMIEAGINVFPASDDPAMFPTTLLNEYLIQHEQIGTSLEHLGRMALAGIDACWLPEPAKSELRARSEAEIADLLAGRPA
>NZ_CP045920.1|WP_153878231.1|2174462_2175848_+|glucose-6-phosphate-dehydrogenase
MTTPTTLLVLGASGDLTRRLLLPGLGSLLERDPDRPLRIVGADRADLGADGFADRLGEALAEGGASDAVLARHRESDYHRLDVTDADEFARVLADVAGDANERLVLYFALPPAVTERACHALTHCDLPPDTHLAMEKPFGRDQESARALNELVARLVPDERVHRVDHFLGKSTVIDVMALRFANRMTQAVWSADHIAAIEIAYDEALALEGRAGYYDHAGALVDMIQSHLLQVMAVVAMEPPSQITGRELRDAKSAVLRATRLWGGDAATASRRGRYTAGTIGERHVPNYLDETGVDPARDTETMAQVTVEVVNQRWRGVPITLRSGKALGHTHKQIVITFEDVRHLPEGFRGADTRDRLIIGLDPDVMELRLTTNGTEDPFELEQSTFATELRRAELTAYGEVLAAILDGEAMLSVRGDAAEECWRLTDEVLAAWKAGTVPMEDYEAGSPVPGDWGPALG
>NZ_CP045920.1|WP_153878230.1|2172465_2174466_+|glycoside-hydrolase-family-15-protein
MDDARSPAARARRSLRSGPARPSPTQPGRYRPLPAPIRADRAGEVAGPVPQPWSGVYGGGVSTPIGDYALLSDRRSSLLVSRTGSIDWLCLPRMDSAAVFSALLGTEEHGRWLMAPREGEVLGRHYEPGTFVLVTRWRTPTGEAEVTEFMPPVDGRSDLVRHVRCLSGTVQIDHELVLRPNYGSTVPWVRRVHDDDGSYLEAIAGPDAYILHGPRLEAADTRHRGSFELHAGHSHSWVLTWVPSHVGGCTPVDVREALRQTRQYWQDWSAQIEAGGSWAGVVRRSLLVLRALTNDETGGIVAAPTTSLPEDPGGERNWDYRFCWLRDSALTLEALLLHGRTEGALHWRNWLLRAVAGDPEDLQIMYGIAGERELPERILDHLPGYADSRPVRVGNAAVNQFQADVVGEVIIALAKLREAGVEEDDFSWPLQRAMIDHVVRHSDDKDQGLWEMRGDPHYFTHSRVMMWAALDRGVRACTDYGLPGPAREWAALRERLRAEILSKGISAETGGFTQTYDNAEVDASLLQIPQTGFIAYDDPIMLATVAQIERDLTKHGLLLRYRTTGTDGLAGDEHPFLACSFWLVEQYAKSGRIPEAYELMDRLVECTSELGLLAEEYDPAGQFHIGNFPQAFSHLTLVRAADAVLSAEIEQVGHAFNETTTEQETP
>NZ_CP045920.1|WP_153878229.1|2171030_2172341_-|hypothetical-protein
MIEFDVYLAITALSVLVICSYVFQLISTKTRIPTVLMLLLLGVGIRELLTSLDRHVEVPLDFIQFFGVLGLILILLEAGLDLNVSRRKLPLVRRATASALFVLAISITGIAAVVHGLLDLPWLTSFVYAAPLAVISSTIVASSIGYLSEDKREFLTYESALSDIFGILLFNVLVAGGGFSIGLVALNVGSIALALVVSVIVSVLLVVLLAKVKVHIKAFLIHPVLMLVYALGHLFNTPTLLTVLIFGLIINNWGQSRHRPLHRYLDPGSVERATETIKSVTSESAFLVRTVFFTLFGYTIDVRVLGDGRVVAVGAAIVATIFAARYVYLRIFVRHHVLPELFFAPRGLVTVVLFYSIPASMTVNAFSDGIVFFVVVATTLVMTVGSLWFTPREATRRVEDARSAREGEGALAARAGEDGEGEPAGVSAAAPGTGRA
>NZ_CP045920.1|WP_153878237.1|2183499_2184261_-|YggS-family-pyridoxal-phosphate-dependent-enzyme
MGGSRRCERESMSELVANLRAVERRIEEAARRTGRDPADVRLLPVSKTVPEERLHEAVAAGCHRLGENKVQEAKRKWQALADLDVSWAVIGHLQTNKAKDVAAFAAEFQALDNVRQAAALDRRLQAAGRGLDVYVQVNTSAEESKFGLVPEELPGFLAELRAYSSLRARGLMTLAVFSAEEARVRECFRLLRTLRDRARESDPDLIGPGELSMGMSGDFELAIEEGATCVRVGQAIFGARATPDSHYWPPAQG
>NZ_CP045920.1|WP_153878238.1|2184377_2185232_-|oxidoreductase
MSDITAAGTLEFTGLGTVTRLGFGAMRLTGPGIWGEPADAETARAVARRAVDLGVDFIDTADSYGPEVSERILAEALHPYPPGLRIATKAGQVRTGPNKWIPVGRAEYLRQQAELSLRRLRVEALDVFQLHRIDPKVELAEQFGVMAELLAEGKVRSLGLSEVSVEEIRIAQTYFPVSSVQNRYSLVQRGSEGVLDHCTDHGIAFIPWAPLDAGRLAAPGGAVDAVATRLGVTHSQVALAWLLQRSPMMLPIPGTGSVAHLEENVAAAGVILDDAALVPLDAAS
>NZ_CP045920.1|WP_153878239.1|2185313_2186243_-|DUF808-family-protein
MAASLFALLDDIAVLARAAASSVDDVAAAAGRASSKAAGVVIDDAAVTPQYVQSISPKRELPVVWRIARGSLLNKAAIIVVIMVLSAWAPGVFPWLLLAGGTYLAYEGAERVWHWLHRRHAPKASATEVLERPAADEDKIVASAVRTDLVLSTEIMLISLASIDVDGWVMRLAVLVVVAVVMTLAVYGAVALLIRMDDVGLWLTRRSAALARTIGAGLVRAMPKVFSLITVVGVVAMLWVGGHILVTNLAEVGWAGPHHVVVAATEAVGGPGALTWVIDSALSAVAGLVWGAVIVVVVGAIGRLRRRRA
>NZ_CP045920.1|WP_153878240.1|2186322_2187927_-|sodium:proton-antiporter
MDAFLIVSVLGLLVIAAATLIASRVGVASPLLLVVLGLLVSLVPAVPEVTIAPEWILAGVLPPLLYSAAASMPSLDFRREFTAIGSLSVVLVIVSALLTGLFFTWVIPGLSLAWGIALGAIVSPTDAVATSIVKRTGISPRVITMLEGEGLLNDATALVLLRAAIAATAAAVSIVGVAGSFALAVAVAAAVGFAAGRLNLAVRSRVSDPTVSTVLSFTVPFLASVPAELLHGSGLFAAVIAGLVTGRGAVRRIPSQHRLAEQQNWRTIELLLEGGVFLLMGLELTGVLDQVIRDHDGYGLAIGAAAGALGVTVAVRTGYVALLVASLGWRARRHRRLRPRLDAVQERISQPGADQRWAENGRRGRRGRQWTLERVRVRVARLSADIDYFLARPFGWREGTVVVWAGMRGVVTVAAAQTLPADTPHRSLLVLIAFIVAAGSLLLQGSSLGAVIRWAKPDTESPVVLAAERRALRELLEEAAAGAPAAASQLAVLAAQRDALLDARDSGRYSSAALSGALEVLDAEQVRLELLGEG
>NZ_CP045920.1|WP_153878241.1|2188039_2188696_-|HAD-IA-family-hydrolase
MGEDGSMAGRHILWDMGGTLLDTYPDVERTLAAVVSEHGSTVDPLTVAFLTRGGPGSSTAGAISELSARFAIPRRAFVGAYDALKRRWRDAPPPVMPGAGEVMGRVFRMGGLNLVVTHRDRASAEALVAARGLEVDDLICAPDGYPRKPDPAMYAAMLERHHLDPADCLAVGDRDVDVAASLAAGIASLRFIVPALPAPAVPHGTFIGDLTEVLPFLG
>NZ_CP045920.1|WP_152909845.1|2188830_2189421_-|helix-turn-helix-domain-containing-protein
MSNLVGYVRVSKREQNPEAQGAELRAAGAARVFVDHSESSWVTDRPQWLACLDYLRPGDTLMVRRLDRIAGSQTMAIQTLNELHKAGVNIKSLTEPDIDTTTPMGRALFGIVAVFAQLRVDTIRENTRRGLAHARAQGRVGGRPSVMTPERIDAAMRMRADGQSIARIAKVLGVGASSVSRALAKVDAEAEATVSS
>NZ_CP045920.1|WP_153878242.1|2189428_2190133_-|hypothetical-protein
MSAESDAQREVARIALAGIAEAGFALAGSGAIREHGVINRPTEDVDLFTTEQDTDEFARAVERVVADLRGSGYEVEEARRAAHFARLAVSTGEGFQFDVDAIRRWGRFTDEELVSAAAARDAGFEVSVFAQQLEAVRRVTLLDVERYGISAEQLSAVNARCMQWAAHLRGRSDGAEVESSRLAELQRSRPSDGFPRAAPRATSQPPRTGLQRGPQVRHGGPYLPGHGSGTGQGR
>NZ_CP045920.1|WP_153879218.1|2190129_2190459_-|transcriptional-regulator
MPQQRVFFRDVKPYEVPEKLEDLKGPVGGVVDLPHTVLWAPGGGRVDLDAEGGAGLAYRAVLSEGTLADQVAVVNRDRLMAVWPGLLLPRRVRELWEARFPELRAVVSA
>NZ_CP045920.1|WP_153878243.1|2191231_2191645_-|glyoxalase
MTTDDTASAPAPTVWPALQARDAHALIEFLVETVGFLRTAVYGDGGTVAHAQLDWPEGGGVMLGSHKSGGEWSLEPGTFGAYVVTDHIDELYARLVAAGATILRELADQDYGNREFAIADPEGNRWSFGPYRGEPRA
>NZ_CP045920.1|WP_153878244.1|2191641_2192523_-|helix-turn-helix-domain-containing-protein
MDGPARLEFVDGAVDGPLRGVIGSMVGYRATGAMPSLHRGVPSPSLTLIVNLDTPIVVGEHAGALADGSARAYENILGSLHVRPAYVFQPSRQAGIQLALHPLAARRLVGVPVRELSDLSTDAADVLGEGIRLLQERIADQAGWPQRFATVERYLLDRAGRAPSVAPARPEVSAAWRWMVANRGRGRMDDLARHVLLSGRQLTRVFRAEFGVTPKAVNRLIRFDRARRIVQSRVLAGRAVRLADIAQETGYFDHAHLVREFHGFLGCSPTDWLAEEVGNIQAGGHRHGEDLRS

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP045920_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045920_6

2419649-2419740

Orphan

Consensus_repeat	Method
CGGCGGCCTCGTCGCGGGCCTCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045920_6

>merge|NZ_CP045920|6|2419649-2419740|CRISPRCasFinder
CGGCGGCCTCGTCGCGGGCCTCCGCCGCGGCCGTGGCCGGGTCGACACCGGCGGCGGGCCCGGCACCGGCGGCGGGCTCGTCGCGGGCCTCC

>NZ_CP045920|6|5|2419649-2419740|CRISPRCasFinder
CGGCGGCCTCGTCGCGGGCCTCC	GCCGCGGCCGTGGCCGGGTCGACACCGGCGGCGGGCCCGGCACCGG
CGGCGGGCTCGTCGCGGGCCTCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045920.1\|WP_152818399.1\|2418067_2418322_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045920.1\|WP_153878367.1\|2410980_2412129_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379523
NZ_CP045920.1\|WP_153878376.1\|2427375_2428035_-\|dihydroxyacetone-kinase-subunit-L	unknown	unknown	gnl\|CDD\|274099
NZ_CP045920.1\|WP_153878380.1\|2431525_2431687_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045920.1\|WP_153878375.1\|2426140_2426563_-\|DUF4233-domain-containing-protein	unknown	unknown	gnl\|CDD\|379420
NZ_CP045920.1\|WP_153879237.1\|2413940_2415017_-\|amidohydrolase-family-protein	unknown	unknown	gnl\|CDD\|238624
NZ_CP045920.1\|WP_153878377.1\|2428031_2429039_-\|dihydroxyacetone-kinase-subunit-DhaK	unknown	unknown	gnl\|CDD\|237724
NZ_CP045920.1\|WP_153878366.1\|2410260_2410704_-\|30S-ribosomal-protein-S16	unknown	unknown	gnl\|CDD\|184724
NZ_CP045920.1\|WP_153878378.1\|2429111_2430602_-\|pyridine-nucleotide-disulfide-oxidoreductase	unknown	unknown	gnl\|CDD\|224169
NZ_CP045920.1\|WP_153878370.1\|2415059_2416655_-\|signal-recognition-particle-protein	unknown	unknown	gnl\|CDD\|236780
NZ_CP045920.1\|WP_153879238.1\|2426587_2427373_-\|HPr-family-phosphocarrier-protein	unknown	unknown	gnl\|CDD\|184702
NZ_CP045920.1\|WP_153878369.1\|2413013_2413775_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|238045
NZ_CP045920.1\|WP_152818402.1\|2425698_2426121_-\|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl\|CDD\|181730
NZ_CP045920.1\|WP_153878371.1\|2416710_2417943_-\|signal-recognition-particle-docking-protein-FtsY	unknown	unknown	gnl\|CDD\|236686
NZ_CP045920.1\|WP_153878365.1\|2410021_2410261_-\|RNA-binding-protein	unknown	unknown	gnl\|CDD\|179479
NZ_CP045920.1\|WP_153878374.1\|2422647_2425485_-\|alpha-glucosidase	unknown	unknown	gnl\|CDD\|236653
NZ_CP045920.1\|WP_153878368.1\|2412132_2413017_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045920.1\|WP_153878379.1\|2430705_2431254_+\|DUF664-domain-containing-protein	unknown	unknown	gnl\|CDD\|368218
NZ_CP045920.1\|WP_153879236.1\|2409361_2409937_-\|16S-rRNA-processing-protein-RimM	unknown	unknown	gnl\|CDD\|234650
NZ_CP045920.1\|WP_153878373.1\|2422105_2422528_-\|nucleoside-diphosphate-kinase	unknown	unknown	gnl\|CDD\|239876

Protein	Function_ID	Function_description	E-value
NZ_CP045920.1\|WP_153878367.1\|2410980_2412129_-\|hypothetical-protein	gnl\|CDD\|379523	pfam14253, AbiH, Bacteriophage abortive infection AbiH. This family of proteins confers resistance to bacteriophage.	8.99075e-11
NZ_CP045920.1\|WP_153878376.1\|2427375_2428035_-\|dihydroxyacetone-kinase-subunit-L	gnl\|CDD\|274099	TIGR02365, dha_L_ycgS, dihydroxyacetone kinase, phosphoprotein-dependent, L subunit. Two types of dihydroxyacetone kinase (glycerone kinase) are described. In yeast and a few bacteria, e.g. Citrobacter freundii, the enzyme is a single chain that uses ATP as phosphoryl donor and is designated EC 2.7.1.29. By contract, E. coli and many other bacterial species have a multisubunit form (EC 2.7.1.-) with a phosphoprotein donor related to PTS transport proteins. This family represents the subunit homologous to the E. coli YcgS subunit.	8.44354e-74
NZ_CP045920.1\|WP_153878375.1\|2426140_2426563_-\|DUF4233-domain-containing-protein	gnl\|CDD\|379420	pfam14017, DUF4233, Protein of unknown function (DUF4233). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 122 and 147 amino acids in length. Proteins in this family are integral membrane proteins.	5.07042e-11
NZ_CP045920.1\|WP_153879237.1\|2413940_2415017_-\|amidohydrolase-family-protein	gnl\|CDD\|238624	cd01299, Met_dep_hydrolase_A, Metallo-dependent hydrolases, subgroup A is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a conserved metal binding site, involving four histidines and one aspartic acid residue. In the common reaction mechanism, the metal ion (or ions) deprotonate a water molecule for a nucleophilic attack on the substrate. The function of this subgroup is unknown.	4.29613e-62
NZ_CP045920.1\|WP_153878377.1\|2428031_2429039_-\|dihydroxyacetone-kinase-subunit-DhaK	gnl\|CDD\|237724	PRK14481, PRK14481, dihydroxyacetone kinase subunit DhaK; Provisional.	0
NZ_CP045920.1\|WP_153878378.1\|2429111_2430602_-\|pyridine-nucleotide-disulfide-oxidoreductase	gnl\|CDD\|224169	COG1249, Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes [Energy production and conversion].	2.5481e-104
NZ_CP045920.1\|WP_153878370.1\|2415059_2416655_-\|signal-recognition-particle-protein	gnl\|CDD\|236780	PRK10867, PRK10867, signal recognition particle protein; Provisional.	0
NZ_CP045920.1\|WP_153879238.1\|2426587_2427373_-\|HPr-family-phosphocarrier-protein	gnl\|CDD\|184702	PRK14484, PRK14484, phosphotransferase mannnose-specific family component IIA; Provisional.	4.40675e-35
NZ_CP045920.1\|WP_153878369.1\|2413013_2413775_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.47355e-09
NZ_CP045920.1\|WP_152818402.1\|2425698_2426121_-\|aminoacyl-tRNA-hydrolase	gnl\|CDD\|181730	PRK09256, PRK09256, aminoacyl-tRNA hydrolase.	8.67456e-46
NZ_CP045920.1\|WP_153878371.1\|2416710_2417943_-\|signal-recognition-particle-docking-protein-FtsY	gnl\|CDD\|236686	PRK10416, PRK10416, signal recognition particle-docking protein FtsY; Provisional.	4.45241e-152
NZ_CP045920.1\|WP_153878365.1\|2410021_2410261_-\|RNA-binding-protein	gnl\|CDD\|179479	PRK02821, PRK02821, RNA-binding protein.	2.5298e-29
NZ_CP045920.1\|WP_153878374.1\|2422647_2425485_-\|alpha-glucosidase	gnl\|CDD\|236653	PRK10137, PRK10137, alpha-glucosidase; Provisional.	0
NZ_CP045920.1\|WP_153878366.1\|2410260_2410704_-\|30S-ribosomal-protein-S16	gnl\|CDD\|184724	PRK14520, rpsP, 30S ribosomal protein S16; Provisional.	2.24237e-64
NZ_CP045920.1\|WP_153878379.1\|2430705_2431254_+\|DUF664-domain-containing-protein	gnl\|CDD\|368218	pfam04978, DUF664, Protein of unknown function (DUF664). This family is commonly found in Streptomyces coelicolor and is of unknown function. These proteins contain several conserved histidines at their N-terminus that may form a metal binding site.	1.95385e-07
NZ_CP045920.1\|WP_153879236.1\|2409361_2409937_-\|16S-rRNA-processing-protein-RimM	gnl\|CDD\|234650	PRK00122, rimM, 16S rRNA-processing protein RimM; Provisional.	5.04216e-39
NZ_CP045920.1\|WP_153878373.1\|2422105_2422528_-\|nucleoside-diphosphate-kinase	gnl\|CDD\|239876	cd04413, NDPk_I, Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside triphosphate (NTP) donor onto a nucleoside diphosphate (NDP) acceptor through a phosphohistidine intermediate. The mammalian nm23/NDP kinase gene family can be divided into two distinct groups. The group I genes encode proteins that generally have highly homologous counterparts in other organisms and possess the classic enzymatic activity of a kinase. This group includes vertebrate NDP kinases A-D (Nm23- H1 to -H4), and its counterparts in bacteria, archea and other eukaryotes. NDP kinases exist in two different quaternary structures; all known eukaryotic enzymes are hexamers, while some bacterial enzymes are tetramers, as in Myxococcus. They possess the NDP kinase active site motif (NXXH[G/A]SD) and the nine residues that are most essential for catalysis.	1.11446e-72

>NZ_CP045920.1|WP_152818399.1|2418067_2418322_-|hypothetical-protein
MTAAVLATVSAIVCALIVIVVILGTRGGDWKHAWSRYRGALRDRSAFTSVRAEAAAIAEPAARTGDLRVGDLWTLGEAEPHPRA
>NZ_CP045920.1|WP_153878371.1|2416710_2417943_-|signal-recognition-particle-docking-protein-FtsY
MTDTFSWLLWIALAIVVLVVGTVVFLRPGRGGRRGPEVPPTRQTPPAGTAERPESDGEGPGTGGVDTLAPPEGDESAGVLDTVDIDGAIEQAAPTLERPESAGTRMERLRSRLARSGALGSALLAVLSRDHLTEADWEELEETLLIADVGSAPTDELMSALRTRSRVAGALDPDSVRGELRTLLLDLVNPAMDRSLETATRLGDDGEPHPATILMVGVNGTGKTTTAGKLARLLVAEERDVVLGAADTFRAAAADQLQTWGERVGVPVVRSDRDGADPAAVAFDAVATGRADGADVVIVDTAGRLQNKAGLMDELGKVARVVGRAAPVSEVLLVLDATTGQNGLRQAQVFAEAVGVTGIVLTKLDGTAKGGIVIAVQRELGVPVKFVGLGEGPDDLAPFSAADFVDALLS
>NZ_CP045920.1|WP_153878370.1|2415059_2416655_-|signal-recognition-particle-protein
MFASLSDRLTASLKSLRGKGRLTDADIDTTISEVRRALLDADVAVPAVRAFTSAVREKAKDADLSKALQPGQQIVKIVNDELIEILGGESRELTLAKRPPTVIMLAGLQGAGKTTLAGKLGVWLREQGHTPLLVAADLQRPNAVTQLQVVGEQAGVAVWAPEPGNGVGDPVLVARAGVEHARAKLHDVVIVDTAGRLGVDEELMRQAANIRDAVNPDETLFVVDAMIGQDAVTTAEAFRDGVGFTGVVLSKLDGDARGGAALSIRTVTGRPVLFASTGEKLSDFERFHPDRMASRILDMGDILTLIEQAEKAFDEQQAAEIAHKISGDGDFTLADFMAQMQQLRKLGSMKKMLGMLPGMGQMRDQLENFDEREVDRIEAIINSMTPGERDNPKILNGSRRSRIARGSGTTVTEINQLLQRFDQAKTMMRSMAKSGGRGMPGMGGMPGMGGMPGAGGMGSLPGSGKKSRGRMAPAPKRKKGKSGNPAKRAQQEREAASQSQASAGSAFGQAPEPADFDPGKLPSDLGDFLKN
>NZ_CP045920.1|WP_153879237.1|2413940_2415017_-|amidohydrolase-family-protein
MERERVRIDGDRLTFASAAGWESGESGEAPESPESLLGWITPGLVDVHCHLGLGPLGAIDEAATRAQADADVRAGVLLVRDAGSPADTAWIRRETGMPRLIRAGRHLARPKRYVRDYAHELDDPDDLPAAMAAQARAGDGWVKIVGDWIDRSDGAAADLRPLWTARQLREGVAAAHGHGARVMVHTFATETVEDLLDAGVDCIEHGTGMTPAQLDRAAEAGVAVTPTLVQIANFAAIADQAGVRYPRYAARMRRLHARRHEQVAAMHAAGVQILVGTDAGGLIRHGRIADEAAELVAAGVPAADVLAAATWAARTYLGAPGIAEGAPADVVVYPEDPRTDIGVLARPSAVFLRGRRVR
>NZ_CP045920.1|WP_153878369.1|2413013_2413775_-|helix-turn-helix-domain-containing-protein
MDLAERISMLRRVNGLSARQLAALVDVAPTTVTRIESGAVSPSFDLAQEILTVLGEPIGFTGAADVGAIAAARLAFDPTLGIEMTPAVDAWRQRWARIGLIDDRGRTVAGKEADLLFRAGRAARLTRRAGAVGFKAGATAFELADALGPAGVDYAVTGDAAANLYRSSAGEAWPVLYVEDVERAAQTAGLVRKDPVSFGMRVTLIPFDGVCELGRTTIDDVTVVARDQVVIDAYGGIDRMAEQADILLGRRVA
>NZ_CP045920.1|WP_153878368.1|2412132_2413017_-|hypothetical-protein
MRDLKAPRTEIEWSRRAIINVVGVLAAHAESLTLVGAHAVLLRTMDLDVPRMPTGDGDLGVTPGLVGDVPSIEALLAEAGYEHRTTARPGLWGRESYDEPDGTRAFREKIDLLAPHGLSGTASRTRRGVPALQPAHGKLAVGNALGLELAAFNRSPLTITDLADARLSARVNVAEVPALILAKGSKIGERLRAPRTGQVRDKDLGDLWRLMAVADPVDTARVIAEFADHAEVGADVRQSIEWTAGVLRDRVNVERAKSTFDTFVDPAEMDHVFELWRDTLTDCVVVPCPDERRG
>NZ_CP045920.1|WP_153878367.1|2410980_2412129_-|hypothetical-protein
MGHREYRASGFDSPGNQHNIIAFVGNGFDVQALSDYGSAVDTRYVSFYHFLKLRSFDEGNPILQEMEKLREEGKEDWSDVEGVVADLLARDPWRATDLSQALRDMQGEFSEFLSLAVPSDLLTALGSDSMDRSLAVGSLSGFLGDLEPEVYRRMGFPGRVQNFDVYNFLFVNFNYTPLLDDFVYLDQKQFDPLPYRTVDRNFVFKGNPSEVANAHVRPGDTFSSYVMTDVVHPHGHQSIPRSLLFGIDEPVRTAGNQDRGLRLAKPFWAQNERRYKHLFADTELYIIFGCSLGESDRWWWRHIAESLGRERSTDDERFEYRPELIIYWFNGGSSVLTQGEVREKFFSAAGLDDPSDAAESVHVVLYDDSTERAWLNTSRAAT
>NZ_CP045920.1|WP_153878366.1|2410260_2410704_-|30S-ribosomal-protein-S16
MAVKIRLKRLGKIRAPYYRVVVADSRTKRDGRVIEEIGKYHPTEEPSLIDIDRERAQYWLGVGAQPTEQVLALLKVTGDWQTHKGLPGTEGTLTVKAEKGDPAEAVKAAEADAELRKARASEAKAAAAAKAAEAPADESADTSNSED
>NZ_CP045920.1|WP_153878365.1|2410021_2410261_-|RNA-binding-protein
MLTDALDHLVRGIVDKPDDVQVTARSLRRGDLLEVRVHPDDLGRVIGRSGRTARALRTVMNALSTDGPVRVDVVDVDRR
>NZ_CP045920.1|WP_153879236.1|2409361_2409937_-|16S-rRNA-processing-protein-RimM
MLLRIATIGAPNGLRGLARLRLHTDRPTERLAVGTTLTSAAGPLTIAALLRRESHWYASFEGYEDRTAVEGLRGVELLTEPESEPDAWYPHELAGLRAEDPTGRVLGQIRGLEYYPAHDVLVLAETSGARTLVPFVAAIVPVVDVPGGRVVIDPPAGLLAGDADDSADTADTADPGDTADRADTTDTDERP
>NZ_CP045920.1|WP_153878373.1|2422105_2422528_-|nucleoside-diphosphate-kinase
MTTERTLVLIKPDGVARSLTGEILRRVEAKGYVLTALEVRAASRELLAQHYAEHEGKPFYEPLVEFMLSGPIVAAVVSGDRVIEGFRSLAGSTDPTGAAPGTIRGDLGRDWGLAVQQNLVHGSDSPESAEAEIALWFPAL
>NZ_CP045920.1|WP_153878374.1|2422647_2425485_-|alpha-glucosidase
MRSMLAATAAAALLAAAVVLPSEAAVADTGPAANGAVPAAADGESNRADRPLPRLASQYRDVLDRTGSPLAFREFDGVGNQRFNPLLDAGAWHGFTLPAEPSEYGGFTGPMVIAEEYSVFFAHELDRLTISADGDPVDLSSATSQEIFAIPGALVQSYDFEGFGLELELRFADDRTALVRTRLVNHTASTQALELTWTGELLDQWTPTATVAETYPDWTRSIEATDDGVRFTFGKLRSTWTIMQSGSAEYRIDRTIAAETTIDKAELSYASTSSIDVPADGSSEFYTLHSYVHSDTEAADLDGSIADIEADPDAYFDASIERWEGYLAAALIDESATAERRRVTVKAVETLNGNWRSPAGEIEHNGITPSNTARWFDGLWAWDTWKGAAALGEFNPEIAKDTIRAMFDSQIQADDPVRPQDAGMVIDAVFYNKLADRGGDGGNWNERNTKPPLTAWAIWDIYKATGDVDFVAEMYPKLRAYHDWWYRARDHDGNGIAEYGATKHPAHNDENGNITFDVRYPGTPPAGLDFTGCEESRGVFACAGDELYRAVLAAGGYNSLSVGAQDGAGWESGMDNAARFGFINNDQLEQYADEAYDGDLERARKDWQVLFLENRADDGSLIGFSINQESVELNAYLAMEKNVLADMAVLLGEPDQAEADRRDAEEIAQYVNTCMFDEESGFYYDRQLAEDAAEAGSCSGALLTDRGRGPEGWSPLWTGIAPADQAARVREVMLDENEFNTLVPLGTASQTNPAYDPEIYWRGRVWVDQFYFGVTALSNYGYDDDAEALTDKFFANAQGLAGDQPIRENYNPETGAMQGATNFTWSAAHLYMLLDPENEGPTEPPTGEPTDEPTDPTTEPTDPGEDPDPTDGTNTSGSDGSDAADGADGSDGSAGADGADSADGAPGGALPDTGAGGATAWFAAALGLLAAGAFALAYRRRSLTH
>NZ_CP045920.1|WP_152818402.1|2425698_2426121_-|aminoacyl-tRNA-hydrolase
MDVQVSPALTIPAAELRWRFSRSSGPGGQHVNTADSRVELSWDIATSAVLSPTQRRRLEGGLAGRLVGTTLTVTASERSSQLRNREVAIARLAELLRAALRPPSAPRRATRPTRGSVRRRRAAKQLRSETKRLRRRPGDD
>NZ_CP045920.1|WP_153878375.1|2426140_2426563_-|DUF4233-domain-containing-protein
MTTAPSSDSPPARPGLPAPAGRSVRHLFAVATLGTQVFVFGFAGLVAYGLRLAPPEVIWPVVGFAVALCLAALALLRGLPGRILGSLVQVVSILAGLIIPMMWILGTVFAALWILAMVLGAKIDREKAAYAAAEAGGRTR
>NZ_CP045920.1|WP_153879238.1|2426587_2427373_-|HPr-family-phosphocarrier-protein
MAVGLVLVSHSGNLAKGAAEVAAQMAPDVPIYAAGGTDDNRIGTSFDRVMEMVERVREAGAEAVVLSDLGSALLTAESVAEVLDGGVTIVDAPFVEGAVAAAVAAQTGSSASQVAAAARTAIDAFAGGSADAADSADDTDHPGGDSAATDSTADTAAPATPAPAAAEATDDHEASSDVLERTVTLRNSLGLHARPAAQVARIVADHDAEVTINETPAASVLALMGLGLTGGAEATLRASGPQAGDVLTRLEEEFENGFGED
>NZ_CP045920.1|WP_153878376.1|2427375_2428035_-|dihydroxyacetone-kinase-subunit-L
MSEKVLGNEWAVAWIQACARITSDERAALNDLDRAIGDGDHGENLDRGFSAVAAKLDSAAPAQLGETFKLVATTLMSTVGGAAGPLYGTAFLRAGKAAGEADNRAGGLDATGVAELLEAGLAGLVARGKAEPGDKTMVDAWDAAATAARAAAESGSDPVAVWAEASAAAEAGARATEPMVARKGRASYLGERSAGHRDPGAQSSAMLLAAAAAAARDTP
>NZ_CP045920.1|WP_153878377.1|2428031_2429039_-|dihydroxyacetone-kinase-subunit-DhaK
MKKLINDPHDVVKEAVAGFVAAHSDLVAAGPDPEELFVHRRGGAVPGKVGLVSGGGSGHEPLHVGFVGEGMLDAAVPGAVFTSPTPGPILAATKAADGGAGVLHIVKNYTGDVLNFETAAELADAEDIDVAAVIINDDVAVQDSLYTAGRRGVAGTVLVEKIAGASAERRDDLATVAAVATKVNERTRSMGVALHACTVPHAGELSFELAEDEIEIGIGIHGEPGRERIPMAGADDITDRLLDAVTTDLGLSGGEEVLLFVNGMGATPLSELYIVYGRAAERLAAAGVKVTRSLVGNYTTALDMQGCSVTVLHLDEELTTLWDAPAKTPAMRSET
>NZ_CP045920.1|WP_153878378.1|2429111_2430602_-|pyridine-nucleotide-disulfide-oxidoreductase
MARIDSQEGERTYDVVVIGAGPVGENVADRVVAGGLNAVVVEHELVGGECSYWACVPSKALLRPGAALRAARAVGGSREAVTAGVDARATLARRTEFTSDWDDSAQVDWLRGAGIDLVRGTARLSGPRRVSVRTTQGPVALEARLAVVVCTGSRAIVPGIPGLAEARPWTSREATSARAVPGSLIVLGGGVVGCESACAYADLGAEVTVIEAGRLLGTLEPVAAEHVRSALAARGVRFHTGATATRVTRDDAAAPDARVTVELSGGERVTGEEILVATGRGPRTDGLGLAVVGLTDGAWLAVDETLRVTGPDGAGIDWLYAAGDVNGRRLLTHQGKYQARIAAGAIMARAARADSGGHGARIDDSPWGAHAATADQRAATAVVFTDPQVASVGLTEADCREQGVRTRVVDVDLGAVAGAALMADGYRGAARMVVDADRQVIVGLTFVGQDVAELAQAGAIAIAGEVPIARLWHAVPAFPTVSEVWLRLLEAYRDGS
>NZ_CP045920.1|WP_153878379.1|2430705_2431254_+|DUF664-domain-containing-protein
MTEDDAATALLLDAFGRIAGGVARVLDGLSAGDAGAQLDGAANSIGWLIWHLTRVQDDHVAELAGVEQVWTAGGWARALDLPFSPTATGFGHTGEEVAALAAVAVGDLATYHEQTQEATAAYLRGLRARDLDQVVDEGWDPPVTLGVRLVSVVSDGLEHLGQAQFVRGVLARRRDGAWSPIG
>NZ_CP045920.1|WP_153878380.1|2431525_2431687_-|hypothetical-protein
MNRRQAVVTALTCIVAGVLSFIVDPWWLVLAVVVSVSLPLLTLAGRSERTGRG

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP045920_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045920_7

2470777-2470909

Orphan

Consensus_repeat	Method
GGCGGGACCGACAGCACAGGTGTGTCCACCGCTCCCGGAACCACCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045920_7

>merge|NZ_CP045920|7|2470777-2470909|CRISPRCasFinder
GGCGGGACCGACAGCACAGGTGTGTCCACCGCTCCCGGAACCACCGTAGTCCCCGCCGAGGCCGGCGAGACCGTCCTGCCCGGAATGGGCGGGACCGACAGCACAGGTGTGTCCACCGCTCCCGGAACCACCG

>NZ_CP045920|7|6|2470777-2470909|CRISPRCasFinder
GGCGGGACCGACAGCACAGGTGTGTCCACCGCTCCCGGAACCACCG	TAGTCCCCGCCGAGGCCGGCGAGACCGTCCTGCCCGGAATG
GGCGGGACCGACAGCACAGGTGTGTCCACCGCTCCCGGAACCACCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045920.1\|WP_153878404.1\|2473153_2474503_-\|6-phospho-beta-glucosidase	unknown	unknown	gnl\|CDD\|133432
NZ_CP045920.1\|WP_152818430.1\|2466269_2467103_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224045
NZ_CP045920.1\|WP_153878411.1\|2481439_2481670_-\|ribbon-helix-helix-protein,-CopG-family	unknown	unknown	gnl\|CDD\|223932
NZ_CP045920.1\|WP_153879241.1\|2472059_2473028_-\|TIGR03557-family-F420-dependent-LLM-class-oxidoreductase	unknown	unknown	gnl\|CDD\|274834
NZ_CP045920.1\|WP_153879239.1\|2464121_2465096_+\|putative-F420-0-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|274826
NZ_CP045920.1\|WP_153879242.1\|2478837_2479644_+\|multicopper-polyphenol-oxidase	unknown	unknown	gnl\|CDD\|376831
NZ_CP045920.1\|WP_153878409.1\|2479822_2480392_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045920.1\|WP_153878403.1\|2467951_2468179_-\|peroxidase	unknown	unknown	gnl\|CDD\|371587
NZ_CP045920.1\|WP_153878400.1\|2462600_2463098_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|274357
NZ_CP045920.1\|WP_153878410.1\|2481257_2481410_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045920.1\|WP_153878402.1\|2465100_2466273_+\|iron-chelate-uptake-ABC-transporter-family-permease-subunit	unknown	unknown	gnl\|CDD\|163581
NZ_CP045920.1\|WP_153878408.1\|2478029_2478830_+\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223472
NZ_CP045920.1\|WP_153878407.1\|2477155_2478022_+\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|224096
NZ_CP045920.1\|WP_153879240.1\|2467086_2467833_-\|coenzyme-F420-0:L-glutamate-ligase	unknown	unknown	gnl\|CDD\|183957
NZ_CP045920.1\|WP_153878401.1\|2463094_2463922_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045920.1\|WP_152818426.1\|2461714_2462446_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045920.1\|WP_153878405.1\|2474566_2475664_+\|carbohydrate-kinase-family-protein	unknown	unknown	gnl\|CDD\|238917
NZ_CP045920.1\|WP_153878406.1\|2475760_2477122_+\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|270452
NZ_CP045920.1\|WP_152818425.1\|2460911_2461667_+\|glucose-1-dehydrogenase	unknown	unknown	gnl\|CDD\|235506
NZ_CP045920.1\|WP_153878399.1\|2460523_2460775_+\|sulfurtransferase-TusA-family-protein	unknown	unknown	gnl\|CDD\|238180

Protein	Function_ID	Function_description	E-value
NZ_CP045920.1\|WP_153878404.1\|2473153_2474503_-\|6-phospho-beta-glucosidase	gnl\|CDD\|133432	cd05296, GH4_P_beta_glucosidase, Glycoside Hydrolases Family 4; Phospho-beta-glucosidase. Some bacteria simultaneously translocate and phosphorylate disaccharides via the phosphoenolpyruvate-dependent phosphotransferase system (PEP-PTS). After translocation, these phospho-disaccharides may be hydrolyzed by the GH4 glycoside hydrolases such as the phospho-beta-glucosidases. Other organisms (such as archaea and Thermotoga maritima ) lack the PEP-PTS system, but have several enzymes normally associated with the PEP-PTS operon. The 6-phospho-beta-glucosidase from Thermotoga maritima hydrolylzes cellobiose 6-phosphate (6P) into glucose-6P and glucose, in an NAD+ and Mn2+ dependent fashion. The Escherichia coli 6-phospho-beta-glucosidase (also called celF) hydrolyzes a variety of phospho-beta-glucosides including cellobiose-6P, salicin-6P, arbutin-6P, and gentobiose-6P. Phospho-beta-glucosidases are part of the NAD(P)-binding Rossmann fold superfamily, which includes a wide variety of protein families including the NAD(P)-binding domains of alcohol dehydrogenases, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate dehydrogenases, formate/glycerate dehydrogenases, siroheme synthases, 6-phosphogluconate dehydrogenases, aminoacid dehydrogenases, repressor rex, and NAD-binding potassium channel domains, among others.	1.81885e-169
NZ_CP045920.1\|WP_152818430.1\|2466269_2467103_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224045	COG1120, FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism].	3.70102e-83
NZ_CP045920.1\|WP_153878411.1\|2481439_2481670_-\|ribbon-helix-helix-protein,-CopG-family	gnl\|CDD\|223932	COG0864, NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain [Transcription].	0.000295615
NZ_CP045920.1\|WP_153878399.1\|2460523_2460775_+\|sulfurtransferase-TusA-family-protein	gnl\|CDD\|238180	cd00291, SirA_YedF_YeeD, SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain. SirA (also known as UvrY, and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA. A variety of microorganisms have similar proteins, all of which contain a common CPxP sequence motif in the N-terminal region. YhhP is suggested to be important for normal cell division and growth in rich nutrient medium. Moreover, despite a low primary sequence similarity, the YccP structure closely resembles the non-homologous C-terminal RNA-binding domain of E. coli translation initiation factor IF3. The signature CPxP motif serves to stabilize the N-terminal helix as part of the N-capping box and might be important in mRNA-binding.	2.43491e-15
NZ_CP045920.1\|WP_153879239.1\|2464121_2465096_+\|putative-F420-0-ABC-transporter-substrate-binding-protein	gnl\|CDD\|274826	TIGR03868, transport_system_substrate-binding_protein, proposed F420-0 ABC transporter, periplasmic F420-0 binding protein. This small clade of ABC-type transporter periplasmic binding protein components is found as a three gene cassette along with a permease (TIGR03869) and an ATPase (TIGR03873). The organisms containing this cassette are all Actinobacteria and all contain numerous genes requiring the coenzyme F420. This model was defined based on five such organisms, four of which are lacking all F420 biosynthetic capability save the final side-chain polyglutamate attachment step (via the gene cofE: TIGR01916). In Jonesia denitrificans DSM 20603 and marine actinobacterium PHSC20C1 this cassette is in an apparent operon with the cofE gene and, in PHSC20C1, also with a F420-dependent glucose-6-phosphate dehydrogenase (TIGR03554). Based on these observations we propose that this periplasmic binding protein is a component of an F420-0 (that is, F420 lacking only the polyglutamate tail) transporter.	1.33598e-130
NZ_CP045920.1\|WP_153879242.1\|2478837_2479644_+\|multicopper-polyphenol-oxidase	gnl\|CDD\|376831	pfam02578, Cu-oxidase_4, Multi-copper polyphenol oxidoreductase laccase. Laccases are multi-copper oxidoreductases able to oxidize a wide variety of phenolic and non-phenolic compounds and are widely distributed among both prokaryotes and eukaryotes. There are two main active catalytic sites with conserved histidines that are capable of binding four copper atoms.	1.99006e-68
NZ_CP045920.1\|WP_153878403.1\|2467951_2468179_-\|peroxidase	gnl\|CDD\|371587	pfam11534, HTHP, Hexameric tyrosine-coordinated heme protein (HTHP). HTHP is from the marine bacterium Silicibacter pomeroyi and has peroxidase and catalase activity. HTHP consists of six monomers which each binds a solvent accessible heme group and is stabilized by the interaction of three neighboring monomers. The heme iron is penta-coordinated with a tyrosine residue as proximal ligand.	7.89869e-37
NZ_CP045920.1\|WP_153878400.1\|2462600_2463098_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	6.74548e-21
NZ_CP045920.1\|WP_153878408.1\|2478029_2478830_+\|ABC-transporter-permease-subunit	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	3.21137e-62
NZ_CP045920.1\|WP_153878407.1\|2477155_2478022_+\|ABC-transporter-permease-subunit	gnl\|CDD\|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	4.65766e-71
NZ_CP045920.1\|WP_153879240.1\|2467086_2467833_-\|coenzyme-F420-0:L-glutamate-ligase	gnl\|CDD\|183957	PRK13294, PRK13294, F420-0--gamma-glutamyl ligase; Provisional.	9.25628e-81
NZ_CP045920.1\|WP_153878402.1\|2465100_2466273_+\|iron-chelate-uptake-ABC-transporter-family-permease-subunit	gnl\|CDD\|163581	TIGR03869, transport_system_permease_protein, proposed F420-0 ABC transporter, permease protein. his small clade of ABC-type transporter permease protein components is found as a three gene cassette along with a periplasmic substrate-binding protein (TIGR03868) and an ATPase (TIGR03873). The organisms containing this cassette are all Actinobacteria and all contain numerous genes requiring the coenzyme F420. This model was defined based on five such organisms, four of which are lacking all F420 biosynthetic capability save the final side-chain polyglutamate attachment step (via the gene cofE: TIGR01916). In Jonesia denitrificans DSM 20603 and marine actinobacterium PHSC20C1 this cassette is in an apparent operon with the cofE gene and, in PHSC20C1, also with an F420-dependent glucose-6-phosphate dehydrogenase (TIGR03554). Based on these observations we propose that this permease protein is a component of a F420-0 (that is, F420 lacking only the polyglutamate tail) transporter.	1.56359e-101
NZ_CP045920.1\|WP_153878405.1\|2474566_2475664_+\|carbohydrate-kinase-family-protein	gnl\|CDD\|238917	cd01942, ribokinase_group_A, Ribokinase-like subgroup A. Found in bacteria and archaea, this subgroup is part of the ribokinase/pfkB superfamily. Its oligomerization state is unknown at this time.	1.05671e-55
NZ_CP045920.1\|WP_153878406.1\|2475760_2477122_+\|extracellular-solute-binding-protein	gnl\|CDD\|270452	cd14749, PBP2_XBP1_like, The periplasmic-binding component of ABC transport systems specific for xylo-oligosaccharides; possesses type 2 periplasmic binding fold. This group represents the periplasmic component of an ABC transport system XBP1 that shows preference for xylo-oligosaccharides in the order of xylotriose > xylobiose > xylotetraose. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.44218e-52
NZ_CP045920.1\|WP_152818425.1\|2460911_2461667_+\|glucose-1-dehydrogenase	gnl\|CDD\|235506	PRK05565, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional.	1.0856e-73
NZ_CP045920.1\|WP_153879241.1\|2472059_2473028_-\|TIGR03557-family-F420-dependent-LLM-class-oxidoreductase	gnl\|CDD\|274834	TIGR03885, putative_dehydrogenase_protein, probable non-F420 flavinoid oxidoreductase. This model represents a clade of proteins within the larger subfamily TIGR03557. The parent model includes the F420-dependent glucose-6-phosphate dehydrogenase (TIGR03554) and many other proteins. Excepting the members of this family, all members of TIGR03557 occur in species capable of synthesizing coenzyme F420. All members of the seed alignment for this model are from species that lack F420 biosynthesis. It is suggested that members of this family bind FMN, or FO, or a novel flavinoid cofactor, but not F420 per se. [Unknown function, Enzymes of unknown specificity].	1.49274e-86

>NZ_CP045920.1|WP_153878403.1|2467951_2468179_-|peroxidase
MAVWLESLITATPQEGFELAITLSRKGVGYTQPSPEAREALRGGYANDADALTAASQVIATNFQTVAAANNYWRD
>NZ_CP045920.1|WP_153879240.1|2467086_2467833_-|coenzyme-F420-0:L-glutamate-ligase
MLLAQAPDGLPVFTSGDDVAALLTPALATLTWPDGSSGLRDGDVVVVASKIIARAEGRLIAAKDREEAIDAESVREVARREYPDGTVLRIVETRHGFVTAAAGIDTSNVPAGTALLLPQDPDASARRLRRGLRARLDLRLGVLVTDTVGRPWRRGAADIAIGAAGIDVLDDLRGQVDLQGRELRATVMAVGDEIAAAAELVRGKTTGRPVAVVRGLHSHVIEDDGPGATAAVRTADEDLFRRGVSGAD
>NZ_CP045920.1|WP_152818430.1|2466269_2467103_+|ATP-binding-cassette-domain-containing-protein
MSAATSTDLRVTDLWAERLTYVISGARARHELLSRVDLSIAAGRITGVLGPNGAGKSTLLRLVIGALRPSSGDLWFGEAGGIGRRSWTTLPPRVRARQLAMVEQDAQPHEDLTVAEVVSLGRLPFQSRLATATAADAELVTAAMERTGVHALADRSFTTLSGGERQRVHLARALAQSPRVLLLDEPANHLDLRAQLDLLEVIGAVAAAGAGVLVALHDIAMAAEICDEVVVLDAGAIAAIGPPREILTPGLIDRVWGVRAEWVHGATGSALVFSPRR
>NZ_CP045920.1|WP_153878402.1|2465100_2466273_+|iron-chelate-uptake-ABC-transporter-family-permease-subunit
MTTTQRPDRGSSAAAPGEAAPGEAVPRRRPPARGRGRVALAGWIVAGLALLVASLVVALTIGPANSTAAGSIEPLRPADVLASAAHHVREALAAIGLGGDPGPGPLSAIREAIVWQGRAPRILVAVFVGSGLALAGAVMQSVTRNPLADPYLLGLSSGASLGAVLVLLLGVGILLPVAAFAGAMAALLLTLSIGGGSAAPHRLVLAGVAVAQGLSALVSFAIFTTARGDSYRDILGWLLGSLSGATWAAVAIAAAATILVGAVLVASARTLDSFAFGEVTAASLGVRVVRSRWLLLTASALLTGALVSVSGSIGFVGLVLPHMVRLVAGTRHRVVLPLAALGGGIFLLWADTAARTLFAPLEVPVGILTAAIGAPVFAVLLARRRRGGGR
>NZ_CP045920.1|WP_153879239.1|2464121_2465096_+|putative-F420-0-ABC-transporter-substrate-binding-protein
MTAAGAAVLLTLAACQGGPDPAARPSPTPSPASSAFPLTVTNCGVEVTLPAPPERVVTIKSAATELVLALGAGDRLVGTAFADGPVPDQWAEEGIPVLAEKLPAAEVVLAAEPDLIVAGWESNLTADGVGERDHLADLGIAGYVLPAACQEPEFQPNPLTFEQVFDQITEVGRILDVPGAAADLVAEQHRLLETIEPATGDLTALWYSSGSDTPFVGGGIGAPELIMSTAGLTNIEAGIDDTWASVSWEAVAAADPDVIVLVDSTWNTAEHKREVLAGNPVTAALDAVANERYLVVPFPASEAGVRTAWAAADLAEQLDALAQG
>NZ_CP045920.1|WP_153878401.1|2463094_2463922_+|hypothetical-protein
MRQDQAGQGPLLDALGELDPAAGLTVDSAALRARIDARIAADEVVDIESIVPARRSRHSMRLALGAVGAGALIVAGAIGLSGLGGSTAYAGWTATPIEVDPQVMVAACPDRLPPWNVMDPDADDIHLSPVLAEQRGPYTLAVMLGRDDATGHDPLGLCMVSQRSDGIVAPLSTTYLDVAAARAEADPVAVQEIVLGWGAEGGAGTFSAVVGTYAAGVTRVQITDGAGSPIEASLNEGWWVAWYPGDNAPGAELTVTADGSVRTLELDSVDFSGPG
>NZ_CP045920.1|WP_153878400.1|2462600_2463098_+|sigma-70-family-RNA-polymerase-sigma-factor
MAASSHARFDELWAHHRELLAFIRRRTEPDIAEDVLAETYLVAWRRIDEVPSEERPWLFTVARNIIRNNYRAAARRRDTAVRIAEGIVPDDGIEGAIATRADLVTAWKRLTAGEQEVLGMVAWDELSHREAAQVLSISSSAFAVRLFRARRRLLHLIEHGRGETT
>NZ_CP045920.1|WP_152818426.1|2461714_2462446_-|hypothetical-protein
MSHSTPARRRAGLTVSILAGLALAATAASLPAAADTAGEAADPGEAAGVVHTRSHAEWQAWAGDLRAELEGTDWAALSRAAGCELTSVSLTEVVDPEANEALGAPADLALPVVEREEHCAPGLAAGAFTQQAPMPAGAFAAAAGSCEGVTGGRACISRSGSYVTGSYTYYGSGTTNGFSRLYKISSLSGCPRGTTMATSGSSTLGYGDRSSITTALGTGSYSMHFWRKVFIGHSDTGGACAYL
>NZ_CP045920.1|WP_152818425.1|2460911_2461667_+|glucose-1-dehydrogenase
MTKFAGRVAIVTGGGSGLGEAISKELALGGASVVVSDIDLAGAERVAGEIAAAGGTASAFRQDVADPEQSRLAVEYAVETYGGLHLAVNNAGIGGVSAPAGEVDLADWQRVIDINLNGVLYGMRYQIPELLKDPHGSAIVNMASIHGTVAAPGNGAYTAAKHAVVGLTKNAAAEYGAAGLRINAVGPGYIVTPLLEKNLPTEALALLATKHPLGRLGRAEEVSALTCFLLSPAASFITGSYHLVDGGYTAV
>NZ_CP045920.1|WP_153878399.1|2460523_2460775_+|sulfurtransferase-TusA-family-protein
MTGPSAPAAVLDNRSAPCAIGLIRAAERVRALAPGQELEVLSRDRFAPYEVPLWAERDGHALLAQERTGLWPRRYWRFRIRRG
>NZ_CP045920.1|WP_153879241.1|2472059_2473028_-|TIGR03557-family-F420-dependent-LLM-class-oxidoreductase
MLEQVGPREAVRLIRRSHEVGLGGVMLADVFQPWTPVQGEAGALWPVLAAAAEHTSGALGAVFTPSYRWHPAVVAQHAATMADLFPGRHWLGLSAGEALNDAITGEYWPRPAERIARLFESADVIGRLFTNSAAGKDTSHDGPHVRLEPVRLWSVPDERPPVLIAAAGPVTARRAGRSADGFITLGGPPERLAGLLDRFRLGAREAGRDPAAATTVVRLHLSWAPDRREAEEQALARWPNGAMRFPKADLRSPFDFAQLARLVRAEDFGDFVHVSADPLEHQAYIQRYLDIGFTHVYLHEVGADQDRWLDVLGEQIMPGLRY
>NZ_CP045920.1|WP_153878404.1|2473153_2474503_-|6-phospho-beta-glucosidase
MRLTILGGGGFRVPLVYSAVTAARHRVPITEVTLHDSDPARLAAMGRVLEDYRGDHPGAPAVRLAASEVEAITGADVVFAAIRVGGTAGRVLDERVALGRGLLGQETIGAGGLAYALRTVPVMERLARLIATHAPDAWVINFTNPAGMITEAMRAHHARVVGICDTPIGLVRRVARVLDLDLGDWSGVDVGYLGLNHLGWLKQLIVDGVDRLPALLADAGLLERIEEARLLGLEWVQTLGALPNEYLYYYYFAREVTASVSGAAATRGEFLDVQQSGFYSQVAEHPGIAHKLWQTTLDEREATYMAEARGADEEREEADQGGGYHEVAIDLMAALLAGERNAMILDVPGDGAIPDLPDDAVVEMPCRVDAAGVHPILPAARLGLDELGLVTAVKGADRLLIEAARTGSRSLAWRAFGSHPLVDSVAVARGLVDDYIAAQPLIARVLTNP
>NZ_CP045920.1|WP_153878405.1|2474566_2475664_+|carbohydrate-kinase-family-protein
MTEPFDVLLSGTVFFDIVFTGFPHPPAPGTEVWTSGMGSSPGGIANLAVATARLGLTTGLVAGFSTDLYGDWMWETLSRQEGIDLSHSCRYADWHTPVTVSLAIDDDRSMVTHGHPTPECVGDRMGDPPPARAVFVDMGDPIMRDAPWWRTAADRGSLVFADAGWDPAQEWDRALLDGLAGVHAFTPNAEEAMGYTRTGSARAALHALTEHVPLAVVTDGARGVIAIDSSTGEEARAEALLVNAVDPTGAGDVFAAALAAGTVRGWPLEQRLRFGVLCSALAVQQFGGSLSAPGWGDVADWWHSVQAQAAAGIPGVDHTRAEYGFLADCLPGEALRAVRRAEATIAAFSDADLHHHPLPPRVIRD
>NZ_CP045920.1|WP_153878406.1|2475760_2477122_+|extracellular-solute-binding-protein
MTSSRWIGIGGIAAAALALAACAPGAGDATGSGEQETPTEVSTDLASLGEITLTVWDQEVRGGQDEQMTRLNEAFQDAYPNITIERNSQSFDDLETTLRGALTGNDAPDVVQANNSRSVMGAFVGAGLLRGLDDYADAYGWTDRYAPSVLAMSSYSDDGTTFGEGHVYGLPQTGEVVGVFYSTSALADAGLDLATVTGSWEDFTDSLATIKDSGATPLELGNLDGWPAVHVFGPIQGQFADPQEIATLAMGNAGGTWLTDANEEAAATLQGWVEDGYFNDGPNGTDYDAAWADFSKGSAAYLIAGSWLAADLEAAMGDDVGFFAPPAPAGRDLATTGATGLPFAITANSPHADAAAGYLDFITSPDAMTILAETGNMPVNDTAALAPATGVNKDVFAAFGEVTTTGHLLPYLDWATPTMADTIGAALQDLIGEQSTPGEFLDTLEADYAAFVG
>NZ_CP045920.1|WP_153878407.1|2477155_2478022_+|ABC-transporter-permease-subunit
MRHPRHLPYLYLAPGLVIFAAFVLYPLARSAQFSLYAWDGLGASTWVGLANYADLLADPVLRAAFGHAFVLIGFFSLVPLALGLALAAILTHGRVRGLGMFRTVVFLPQVIAMVVVAVAWRQIYAPDGTLNTALRAIGLDNLAIPWLGDYTWTLPAVGVVGTWVQLGLVTVLLMAGMAKLPKEMYEAARIDGAGPVREFFAMTAPNVRAEMAVALTLTIIAALKTFDLVYVTTGGGPGNSTTVPAYEVYTRAFREGAVGSAAAIAVTLAILIFGINLIVNKLVDRPAG
>NZ_CP045920.1|WP_153878408.1|2478029_2478830_+|ABC-transporter-permease-subunit
MIVSRPERVMNYVVLLVFAAFALAPILVILTTALAPSTTSPGGLATFASAWTQGRFGHYLSVSALVAVVVVTTATLCSILAGYALGTMTFRGSGIVFSLFLLGLMIPTEAIVVPLFYDLRGLGLTNTLWAVAFPQIAQSIAFGAYWMRAYFRAAPRALIEAATLDGASPRRVLWSILVPIGRPAVTTLVLLTFMWTWNEFLIPLVMSPNGAFRTAPLALALFKGQHVEATGLLAAGAVLVALPVVVLYLFLQRHFIRGMIEGAVRE
>NZ_CP045920.1|WP_153879242.1|2478837_2479644_+|multicopper-polyphenol-oxidase
MDGARSPRRGVVAVDLGPGVRAFFTTRAGGASGAGFAGLNLGHHVGDDPAAVRANRALVDAWAGAPVAYADQVHGVRVLDPARLPHADSRHMPISPGSSRPAGSNAAPPTGDAWCTASTTPVAIMVADCTPLLLADPEAGVVAAAHCGRAGLAAGVVPATLAAMIRAGAAPDRVRAAIGPGICGECYEVPASLRAEVSGVVPTTGSTTSWGTPAIDIPAGIRAQLAAAGVRDVTDTGLCTLTDERFFSYRRAAGAPTGRFAGVIGLLR
>NZ_CP045920.1|WP_153878409.1|2479822_2480392_-|hypothetical-protein
MWAPTKIENIAAWALVATPILWQLVSIALLQMSFSSVSAGAMLIFFAGNSLLCAWDVMNLRKAGLAPRVSTWFAAIFLVPAYLVSRTLRSKQTWWIPSLWVASFLLAIAMMPLVAIAGGVEYEADFLEDEIESDLAEYYLLPNSRVSCPDPAIAPVGSIIECDVFFADGTSDSAIIDVLDWTGTWNWSM
>NZ_CP045920.1|WP_153878410.1|2481257_2481410_-|hypothetical-protein
MSNDRTNVTVTRVGRGATMVVPLTSYVSRMFPFQAARPAVETGIDRDSVA
>NZ_CP045920.1|WP_153878411.1|2481439_2481670_-|ribbon-helix-helix-protein,-CopG-family
MKITIRLSDEDLAVLDDVVRRAGLPSRSAAVRRAIGLLRHPDLEGDYAAAWEEWSSSGEATAWAATSEDGLADAPP

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP045920_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045920_8

3002430-3002590

Orphan

Consensus_repeat	Method
CGTTGCGGTGGCACAGCTTCTTTCCCCA	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP045920_8

>merge|NZ_CP045920|8|3002430-3002590|CRISPRCasFinder
CGTTGCGGTGGCACAGCTTCTTTCCCCACCTCGCCCTGCCCACCTCGCGGGGAGACTCGCCGTTGCGGTGGCACAGCTTCTTTCCCCAGGTGCGGCCGCATCGGCCCGGCGTCGTGAAGCTGGGGAAGCTCGTCGTTGCGCAGGCACAGCTACTTTCCCCG

>NZ_CP045920|8|7|3002430-3002590|CRISPRCasFinder
CGTTGCGGTGGCACAGCTTCTTTCCCCA	CCTCGCCCTGCCCACCTCGCGGGGAGACTCGC
CGTTGCGGTGGCACAGCTTCTTTCCCCA	GGTGCGGCCGCATCGGCCCGGCGTCGTGAAGCTGGGGAAGCTCGT
CGTTGCGCAGGCACAGCTACTTTCCCCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045920.1\|WP_153878709.1\|2997523_2998234_+\|PIG-L-family-deacetylase	unknown	unknown	gnl\|CDD\|225031
NZ_CP045920.1\|WP_152910343.1\|2996607_2997492_+\|formyltetrahydrofolate-deformylase	unknown	unknown	gnl\|CDD\|235676
NZ_CP045920.1\|WP_153878714.1\|3012192_3012468_-\|DUF3017-domain-containing-protein	unknown	unknown	unknown
NZ_CP045920.1\|WP_153878715.1\|3012753_3013464_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045920.1\|WP_153877410.1\|2998560_2999358_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|366760
NZ_CP045920.1\|WP_152910341.1\|2992573_2993836_-\|serine-hydroxymethyltransferase	unknown	unknown	gnl\|CDD\|234571
NZ_CP045920.1\|WP_153878713.1\|3009885_3012117_+\|NADP-dependent-isocitrate-dehydrogenase	unknown	unknown	gnl\|CDD\|377178
NZ_CP045920.1\|WP_153879285.1\|3002685_3004134_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|366234
NZ_CP045920.1\|WP_152910334.1\|2996026_2996548_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP045920.1\|WP_153878711.1\|3005511_3008577_-\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|377950
NZ_CP045920.1\|WP_153878718.1\|3016539_3017676_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226614
NZ_CP045920.1\|WP_152910332.1\|2995136_2995436_+\|MTH1187-family-thiamine-binding-protein	unknown	unknown	gnl\|CDD\|376658
NZ_CP045920.1\|WP_153879153.1\|2999354_3000902_-\|IS21-family-transposase	unknown	unknown	gnl\|CDD\|366234
NZ_CP045920.1\|WP_153878710.1\|3004182_3005478_-\|DUF559-domain-containing-protein	unknown	unknown	gnl\|CDD\|380141
NZ_CP045920.1\|WP_153878712.1\|3008747_3009731_-\|malate-dehydrogenase	unknown	unknown	gnl\|CDD\|235468
NZ_CP045920.1\|WP_153879284.1\|2991710_2992565_-\|bifunctional-5,10-methylenetetrahydrofolate-dehydrogenase/5,10-methenyltetrahydrofolate-cyclohydrolase	unknown	unknown	gnl\|CDD\|223268
NZ_CP045920.1\|WP_152910333.1\|2995451_2995997_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045920.1\|WP_153878717.1\|3014808_3016446_-\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	unknown	unknown	gnl\|CDD\|234854
NZ_CP045920.1\|WP_153877139.1\|2994193_2995105_+\|IS982-family-transposase	unknown	unknown	gnl\|CDD\|372648
NZ_CP045920.1\|WP_153878716.1\|3013473_3014742_+\|pyridine-nucleotide-disulfide-oxidoreductase	unknown	unknown	gnl\|CDD\|369639

Protein	Function_ID	Function_description	E-value
NZ_CP045920.1\|WP_153878709.1\|2997523_2998234_+\|PIG-L-family-deacetylase	gnl\|CDD\|225031	COG2120, COG2120, Uncharacterized proteins, LmbE homologs [Function unknown].	1.53513e-35
NZ_CP045920.1\|WP_152910343.1\|2996607_2997492_+\|formyltetrahydrofolate-deformylase	gnl\|CDD\|235676	PRK06027, purU, formyltetrahydrofolate deformylase; Reviewed.	1.26264e-174
NZ_CP045920.1\|WP_153877410.1\|2998560_2999358_-\|AAA-family-ATPase	gnl\|CDD\|366760	pfam01695, IstB_IS21, IstB-like ATP binding protein. This protein contains an ATP/GTP binding P-loop motif. It is found associated with IS21 family insertion sequences. The function of this protein is unknown, but it may perform a transposase function.	5.76738e-53
NZ_CP045920.1\|WP_152910341.1\|2992573_2993836_-\|serine-hydroxymethyltransferase	gnl\|CDD\|234571	PRK00011, glyA, serine hydroxymethyltransferase; Reviewed.	0
NZ_CP045920.1\|WP_153878713.1\|3009885_3012117_+\|NADP-dependent-isocitrate-dehydrogenase	gnl\|CDD\|377178	pfam03971, IDH, Monomeric isocitrate dehydrogenase. NADP(+)-dependent isocitrate dehydrogenase (ICD) is an important enzyme of the intermediary metabolism, as it controls the carbon flux within the citric acid cycle and supplies the cell with 2-oxoglutarate EC:1.1.1.42 and NADPH for biosynthetic purposes.	0
NZ_CP045920.1\|WP_153879285.1\|3002685_3004134_-\|IS3-family-transposase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	1.84895e-21
NZ_CP045920.1\|WP_153878710.1\|3004182_3005478_-\|DUF559-domain-containing-protein	gnl\|CDD\|380141	pfam18741, MTES_1575, REase_MTES_1575. Vsr REase Fold. Fused to HEPN (SWT1/Abi2 family), along with Transglutaminase and wHTH.	4.55392e-13
NZ_CP045920.1\|WP_153878711.1\|3005511_3008577_-\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|377950	pfam07971, Glyco_hydro_92, Glycosyl hydrolase family 92. Members of this family are alpha-1,2-mannosidases, enzymes which remove alpha-1,2-linked mannose residues from Man(9)(GlcNAc)(2) by hydrolysis. They are critical for the maturation of N-linked oligosaccharides and ER-associated degradation.	5.25688e-118
NZ_CP045920.1\|WP_153878718.1\|3016539_3017676_-\|hypothetical-protein	gnl\|CDD\|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	5.60133e-24
NZ_CP045920.1\|WP_152910332.1\|2995136_2995436_+\|MTH1187-family-thiamine-binding-protein	gnl\|CDD\|376658	pfam01910, Thiamine_BP, Thiamine-binding protein. The crystal structure of two of these members shows that this domain has a ferredoxin like fold and is likely to exists as at least homodimers. Sulphate ions are are located at the dimer interfaces, which are thought to confer additional stability. Although the function of this domain remains to be identified, its structure suggests a role in protein-protein interactions possibly regulated by the binding of small-molecule ligands. Solution of the structure of the hyperthermophilic anaerobic Thermotoga maritima sequence, UniProtKB:Q9WYV6, shows that this has a beta-alpha-beta-beta-alpha-beta ferredoxin-like fold and assembles as a homotetramer. It was possible to identify a pocket in each monmer that bound an unidentified ligand. It was also found that it bound charged thiamine though not hydroxymethyl pyrimidine. It is proposed that it is transporting charged thiamine around the cytoplasm. Under oxidative conditions this bacterium is under stress, and the transcriiptional unit within which this protein is expressed is up-regulated in these conditions, suggesting that the chelation of cytoplasmic thaimine is part of the response mechanism to such oxidatvie stress, which is mediated by this family.	4.50319e-33
NZ_CP045920.1\|WP_153879153.1\|2999354_3000902_-\|IS21-family-transposase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	4.20913e-17
NZ_CP045920.1\|WP_152910334.1\|2996026_2996548_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	3.55369e-12
NZ_CP045920.1\|WP_153878712.1\|3008747_3009731_-\|malate-dehydrogenase	gnl\|CDD\|235468	PRK05442, PRK05442, malate dehydrogenase; Provisional.	0
NZ_CP045920.1\|WP_153879284.1\|2991710_2992565_-\|bifunctional-5,10-methylenetetrahydrofolate-dehydrogenase/5,10-methenyltetrahydrofolate-cyclohydrolase	gnl\|CDD\|223268	COG0190, FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase [Coenzyme metabolism].	1.01538e-98
NZ_CP045920.1\|WP_153878717.1\|3014808_3016446_-\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	gnl\|CDD\|234854	PRK00881, purH, bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional.	0
NZ_CP045920.1\|WP_153877139.1\|2994193_2995105_+\|IS982-family-transposase	gnl\|CDD\|372648	pfam13612, DDE_Tnp_1_3, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contains three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	3.30469e-14
NZ_CP045920.1\|WP_153878716.1\|3013473_3014742_+\|pyridine-nucleotide-disulfide-oxidoreductase	gnl\|CDD\|369639	pfam07992, Pyr_redox_2, Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.	1.26671e-40

>NZ_CP045920.1|WP_153879153.1|2999354_3000902_-|IS21-family-transposase
MEILEAYDATQSAHSAAQLAGVDPKTVRRYVAARDQGRAVTGAGRRPRMIDEHMPKIEEWVERGNGKVRADVIHGRLVAVGFTGTERTTRRAVAEVKAAWRAGHRRSYRPWITEPGLWLQFDWGEGSRVPGPDGKPRRTWLFCAWLAWSRFRVVIPVWDQTLPTLIACLDATLRRLGGVPSYILTDNAKTVSVEHVAGVAVRHPQIVQVARHYGSQVHTCVPYDPESKGGTESTVRLAKADIVPTGANLREQYSSFAQLEQACEEFMTKVNNRKHRESARLPAEALIEERARLHMLPAAPHTMALGETRSVGTDQTIRFGSVRYSTPPGLVEEEVWVRAAGAELIIVADLDALPLVPDWATDRRGLVEVARHRLSTPGNPRIDLAHYPDHPQEPDGAPRPPKPRARNAAEEEFLALGRGAYDWLIEASAAGAVRIRAKMADAVQLATLVGREGVDAALGVAAAAGRFGEGDLAAIVDHQAVGATATDLVVADEAHSAQPGTTAWANFTTSKETTR
>NZ_CP045920.1|WP_153877410.1|2998560_2999358_-|AAA-family-ATPase
MSPTAVTTTTTPAAPPLPSDLEQAMRRMRLPYLRAAAPDVLATAKSQRWDPAEILRVLLAEEVRGRDEATKTARRKAAGLPAGKTLHSWREHDSSIPAPTQSALATLEWIHHRENLAISGPSGTGKTHFVEALAHKAIDEGMPVAWFTLESLTTAISRATVDGSISKVLAKITRAELVVIDDIGMLPAGQAAAEAFYRLVDATYERRSLAVTSNIHPAGFDTIMPKTLATATVDRLLHHAHVIVTEGTSQRLTEATNGRGVIPLT
>NZ_CP045920.1|WP_153878709.1|2997523_2998234_+|PIG-L-family-deacetylase
MELQPLDEDWERAVAIVAHPDDMEFGAAGAIARWTAQGKHITYVMVTSGEAGIDSMAPDRAGPLREREQVDSCRIVGVEDVIFLRRPDGTLEHSLELRAALCEQIRRLRPQIVMTNSYRETWPGGLLNQADHIAVGRASVDAVRDAGNRWIFPDAGGGLERWDGVRQVWLPGSPAAGHAVDISATFEVGLDSLRAHAAYIEGLGGFDPAGFLDAGATAAGERLGCRYAATFEVLQP
>NZ_CP045920.1|WP_152910343.1|2996607_2997492_+|formyltetrahydrofolate-deformylase
MSGRAATLAVVTDSAPQWVLTLSCPDRPGIVHAVAGAVAGIGGNITESQQFGDPESGLFFMRVQVESGAGEGPLRSVLEPVASSFGMTWTLDRVGRAMRTIVMVSTTAHCLTDLLFRQRSTGLPTDIVAVVSNHTTLAPIAEFYGVPFHHIPVTKATKAEAENRLLELTAELDAELVVMARYMQILSDDLCRALPGRIINIHHSFLPSFKGARPYAQAHARGVKLIGATAHYATADLDEGPIIEQDVERVTHAEDPTELMRLGQDVERRVLARAVRWHAEHRVLLDAHRTVVFR
>NZ_CP045920.1|WP_152910334.1|2996026_2996548_-|GNAT-family-N-acetyltransferase
MSEDLRIDLVEQSCAGELLTVRRAAFVTEAQLYGDPNIPSLTQTLAELEADLDRADVVTLGAWTGSRLVGSVRVGLEEDRALLGRLAVVPDLQGQGIGTQLLMAVLHYLPEDTKEVWVFTGQDSKQNLAMYDKHGFEHQYDQNAGDLTYAYLRKILGDGPDEAQTEHEVDSAS
>NZ_CP045920.1|WP_152910333.1|2995451_2995997_-|hypothetical-protein
MHALTTRHALAAGALAAALLASLSGCESGDDGGSPTPPASPPASVTPSEPGPNESAPTGSQSDTASPTSTPTPTPTRSETGGTDAPIPTDAADYADALIVAWGSGDHDRMVELATPEVVEELTGHADPGGPHWDRVGEDSGAGSTFVRYEDTSTGETVELRVELQAAGQGREHAVAEVKFG
>NZ_CP045920.1|WP_152910332.1|2995136_2995436_+|MTH1187-family-thiamine-binding-protein
MLVAISISPSAGDETGGVSDAVAKAVRVIRDSGLPNETTAMFTTIEGEWDEVMAVVKAALDAAGEGSPRVGLVLKADIRPGFTNQLTEKVDRVEARLTD
>NZ_CP045920.1|WP_153877139.1|2994193_2995105_+|IS982-family-transposase
MDADLDTLATELYVTTDDLLKAHPEECPLRPLVGLAPQISDAELITLAVMQALLGHTNETRWLRYAHTHLHAMFPYIPRQSGYNKRLRALVGTVAWLIRALASQTSVYDDDVLLVDSTPIECARSRETVHRSDLAGWAQYGYCASHSRYFWGLRLHMIATVHGLPIAFAITGAKADERTVVLELLQTDQSLAGRARSILIGDKNYFGHQFETDLADHDIELLRPARKGEKPRPGARFFKPLRQTIESIFDTFKGQLDLERHQGRTPAGVLIRILQRILALTAAIWHNDRTGQPIRRSLTAYDH
>NZ_CP045920.1|WP_152910341.1|2992573_2993836_-|serine-hydroxymethyltransferase
MPLAELDPEIAAVLEGELVRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGYPGRRYYGGCEQVDIAESLAIERAKSLFGADYANVQPHSGATANAAVLHALIKPGDKILGLSLAHGGHLTHGMKINFSGKLYDVAAYGVAEDTHLIDYDALRARAIEEQPKVIIAGWSAYPRHLDFEAFRSIADEVGAYLWTDMAHFAGLVAAGLHPNPVPFSDVTSTTVHKTLGGPRSGLILSRDGETFGKKLDSAVFPGQQGGPLMHVVAAKATALKVAAGADFRERQARTISGARIIADRLLAEDVKKAGVSVVSGGTDVHLVLVDLRHSDLDGQQAEDLLHAAGITVNRNAVPFDPRPPRVTSGLRIGTPALASRGFGDEEFTEVADIIAGLLATGAGADVEAAKARVAKLTGAFPLYPGLQQ
>NZ_CP045920.1|WP_153879284.1|2991710_2992565_-|bifunctional-5,10-methylenetetrahydrofolate-dehydrogenase/5,10-methenyltetrahydrofolate-cyclohydrolase
MLPGGPVADAVLAGLAPRIAALTAAGHTPGLGTILVGSDSASAGYIRMKQTKATELGFTAPHIHLGDDATQADVLAAVADMNEASDVDAVLIQHPTPPQIDFDAALLALDPDKDVDGLHPVNMGRLALGMPGPVPCTPAGIEAILAHYEIEVSGRHVVILGRGTTLGRPLALLLSQKRPTANAAVTVVHTGVPDWADYTRRADIVIAAAGVPGILQPEHLTPGVTVIGGGVRYEGRRLLPDVDEACEQVAGAITPRIGGVGPTTIAMLFKNAVEAAERRAGLAA
>NZ_CP045920.1|WP_153879285.1|3002685_3004134_-|IS3-family-transposase
MNENSQEDPAGAGPRAGGPKRRRFTPAQKLAHVQAYEQALADGDAGAYLRREGLHSASISEWRRLRDAGVLEGKEPGQAVGRPNREQAEIGRLRRQLEVTQNELDQTRTALEIMGKTHTALGADLQERAGRARAHEALMATHEELTGAGITTREAARLTGISRATAARHGKARPAPTPLDRADPVNRLSCAEREVVLEVLDSPEFVDSTPMQVYATLLERGVYLCSVSTMYRILREDDQVVDRRRQARHPARTVPELVATGPGQVYTWDITKLPGPAKGVYYDAYVMLDIYSRYIVGAIVHARESGPLAEEMMREVFGIHGIPHVVHADRGTSMTSKSVAVLLEDLQVVRSHSRPRVSNDNPYSESLFKTAKYSPTFPDRFGSLDDARAWMAEFTEWYNHEHHHSGIGLHTPADVHYGHADQIATDRQATLAAARAAHPQRFSTNHAPKILDLPTAAWINQPDDEHDQSTKEDSNPAYEQAA
>NZ_CP045920.1|WP_153878710.1|3004182_3005478_-|DUF559-domain-containing-protein
MLTRRARWGFAVLTACAGKFVGAVPRRCSPQSWCRGPALAGYRAAAATPLCPDCTVMHRCPQLRPHHVRGHRLALPPGVMTTPRNLKTAPFEDALDAASPHGEPPPPSPPARARRRQSEADAAGLFRTQHGLIARGQVLATGLTDEHIRHRLALGLWVRVYSGVYCLAGTRRTRLCRCVAALLYCGPNAYLSHDTAAYELGLIYRPYSATIHVTLPHSTRVRAQTGLKIHRTRLPAEPRRTSTGLVVADPVRTLVDLAATLSSRDLQAVLHDGIFKKIVTLNALYDGLSEPRHVPGFSPMRREIEVFDRESDSGREAEAGRLFRRAGMSFIRRYEVWGDEGGHAILDFAHVPLKLDVEIDGAAYHADPAAQARDRERDRMLIRLGWQVLRIPATDVRTRPDDVVELVRAALAQRPTCQAELRPGPHSKYDS
>NZ_CP045920.1|WP_153878711.1|3005511_3008577_-|LPXTG-cell-wall-anchor-domain-containing-protein
MSIRSTSRPIGRRRPTSGSVWRGRVLGTGATLALVATAAVAPATAEPGADWEAGEPLDLTQYVDPHIGTAVSSTSGYAGNVSPGAKVPFGMVTFGPDMSRSNYNGSGGYILPASATSGRINFFSLTHINGPGCPGQGVVGMLPRTDATSVTNAAGAPQQAAEFQTANESAAPGAYSVTLDSGVEVELGATTRTGVATFTYPDADSAYFSLDTRLNANSNARNDAGKISPENVSLEVSEDGTVLTGKTVAPAFCTPWGTPYNSNVYFYAELDRTLEAQDDTDDTEGAESTVNTVVDGSTVLQYDVPADDPTLTLRVGISSVSIANAEENLAAEAPTATLDQVRAQADDLWNERLNTVQVDRAADPDALTEEQRDELVKFYTSLYRALGSPTVYSDVNGEFRSMEAPELLSGEPDRGGYVQERETVNVSDYDYTKANGETGGYDTHYSSLSFWDTYRTQAQLLALLAPDVASDVAQSTIVDGLQCGALPHWVDASDDSTPMSGDNALPVIAATYAFGARDFDLAAAARFVSQSSFDETSACNGNASFAGMADYLETGYYPEGDWTSANIERYNSDYAAAEFLAAVRDVVADDVTITDDQVDVLYDRAGWWTTILDPETDTLRSRVAPTEPGVPGEFGTGTFHESTEPNYFWSFAHAWDGLIEGIGGNEAAIDRLDALFSMDDELTATPTLAELNGGQDADTFYMGNEPSYQAPWAYNWAGKPAGTQYVISQLRTTAFGTDRDGMPGNDDLGVQSAWYVFASLGLFPVVPSEAGLAISSPMFPAATVWLDGKPVRITTDSDPAAAPFIETMTVDGNAYGRSWMKAETLANASEISFGLSSTPTTWAADVHPSDAAATTTGLELSATTIKAGASATATVTVDSADLTVPQGTIELRVDGTVVAEAPIGAETGTIEIPLTVPAETPASTVSVTAAFVPSDPTFLEPSASEPVALEVTPAPGPTPEPTDEPTDEPTDTPTDAPTDTPTGDQDGLDELPDTGITVTAWIVAALLLAAGGLVLRRRQSA
>NZ_CP045920.1|WP_153878712.1|3008747_3009731_-|malate-dehydrogenase
MTTPVNVTVTGAAGQIGYALLFRIASGQLLGPDTPVRLRLLEIPPAVKAAEGTAMELDDCAFPLLAGIDIVDNPSDGFAGTNVALLVGARPRGAGMERADLLEANGGIFAPQGKAINDGAAEDIRVLVVGNPANTNALIAASHAPDVPADRFTAMTRLDHNRALSQLAAKTGAGVADIKNLTIWGNHSASQYPDVFHATVGGRPAADLVAESWLAEEFIPTVAKRGAAIIAARGASSAASAANAAIDHVRDWVLGTPADSWTSAAVVSDGSYGVPEGLISSFPVRSASGAWEIVQGLEVGDFSRARIDASVAELGQERDAVRGLGLI
>NZ_CP045920.1|WP_153878713.1|3009885_3012117_+|NADP-dependent-isocitrate-dehydrogenase
MTESTIIYTHTDEAPALATSSFLPIIRAFAGSAGVEVATRDISLAGRILAHFPERLTPEQQVGDALAELGELAKHPGANIIKLPNISASVPQLKAAVAELQRAGYDLPNFPDSPATDAERDVRARYGKVMGSAVNPVLREGNSDRRAPASVKNYARNHPHSMGAWSPDSRTNVATMGTDDFASSEQSVVLAADDTLRVELRGADGTVTVLKEAIPVLAGEIVDATRMDAAALESFLAAQVQRAAEAGVLLSVHLKATMMKVSDPIIFGHAVRAYFSGVFAAHGDDLAAAGLSPNDGLAAIFAGLDALDDQAKATEIRAAFEQSLADGPDLAMVDSDRGITNLHVPSDIIIDASMPAMIRTSGKMWGPDGGQADTLAVIPDSSYAGVYQAVIEDCRTHGAYDPATMGTVPNVGLMAAKAEEYGSHDKTFEIPAAGVVAVLDSAGTVLMQHDVNAGDIWRACQTKDIPVRDWVKLAVDRGRATGDPIVFWLDENRAHDANLIAKVNDYLPTHDTAGLDIRILSPIEATRLSVERIRAGLDTISVTGNVLRDYLTDLFPILELGTSAKMLSIVPLIAGGGLFETGAGGSAPKHVAQLVAEDYLRWDSLGEFLALAVSFEHLAKTTGNARAQVLADTLDAATGTFLEENRSPGRRLGTTDNRGSHFYLAQYWAKELAAQTGDAELAELFAPVARALTENEETITSELLAVQGKPADIGGYYLPDEEKVAAVMRPSTTLNGIIEALTK
>NZ_CP045920.1|WP_153878714.1|3012192_3012468_-|DUF3017-domain-containing-protein
MSTDPVTLARGRTAVLWLAVAGVVVMIAASFTLGARTGISILGAELLVLAAVRACTSWADRIASRSRSFDVVLLAGIGVAILVLGLTADNV
>NZ_CP045920.1|WP_153878715.1|3012753_3013464_+|hypothetical-protein
MTDAHRGVLGLRVRARGRLAPGSGTRPLHEPFVGNRSIRLAGDLPASAAELPVQVSARLTPDGLVATAVRPCDPAELADPHPANVLRGLRRRIDPGLVSPGADPTSPRLTAALDELLAAGRIRDRTRISLARGVRVLVVVVTGGGVREELERVDPLGVSAVVLTPARWSGDEEVEARALLDLIPEPDVVASGRGITAHGDVGLLLRTVHAPTEPISAALARLPAGLVTLTNWIEPD
>NZ_CP045920.1|WP_153878716.1|3013473_3014742_+|pyridine-nucleotide-disulfide-oxidoreductase
MNRIVIVGAGLAGLRTATELRERGYDGEVVVIGDEPHPPYDRPPLSSELLTRAEPLWLADDLGTALADVADRVITGRAARLEPGAESVVIMDDGARLEASAVVLAMGSAPVRRWPEPLTLHTLEDAALLRAALAAPARLAIIGAGWIGSEVAGQAAAAGHEVTVFEAGPAPLADHIGVRAGDYTRAWHEAAEVDLRTDTPVHAVDPAGGTGAGLRAIVRTGDGDIEADAVLAATGVRPNTDWLAGSGIPVTERGFVPVTVDGRVSPRDATVEATGADTPRVWAVGDVALRDHPRHGPLAGGHWFSALRDPAGVAAGILGPERAEPAPNLLAPEVFSDQFGHHLERIGDLAGPGGTEVLRGDPGAGWTLLQIRENRLVGAIVADSPRDTSAVRKAFQRAGEDYPRIDLDLATDPAVQLRKALT
>NZ_CP045920.1|WP_153878717.1|3014808_3016446_-|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase
MRADRLGRGGPPNRCHTYPWSLVVSDRLPIRRALVSVYDKTGLAALAAGLHEAGVEIVSTGSTAQAIAAAGVPVTGVEDVTGFPECLDGRVKTLHPKIHAGILADRRLPEHVRRLEELGVAPFDLVVVNLYPFADTVASGAEVEDCIEKIDIGGPSMVRAAAKNHASVAVVVDPTRYEAVLAAVTAGGFDSRDRAGLAVDAFRHTATYDVAVATWLGTVVAPDDEGTGFPGWKGATWERSRVLRYGENPHQGAALYTDARGGGLAGATQLHGKEMSYNNYVDADAAWRAAHDHGDTPTVAVIKHANPCGVAVGETIAQAHARAHATDPVSAFGGVIAANAVVTEEMADQVAGVFTEVVLAPGYEPAALEILSRKKNIRILTVAGSAALAGAAVAEREIAGGLLSQQVDRIDAAGDDPANWTLAAGAAADEATLADLAFAWRAVRSVKSNAILLAAGGAAVGVGMGQVNRVDSCRLAVERAGERASGSVAASDAFFPFADGAQVLMDAGVRAIVQPGGSVRDQEVVDAATAAGVTMYLTGTRHFAH
>NZ_CP045920.1|WP_153878718.1|3016539_3017676_-|hypothetical-protein
MTISGEPEERLDRRRLLVLARQHARQGRRRVRSAALPVLVAAVAAGVAWAVAHYGLGHEQPFFAPIAAWVCLGFSPSRQIRKVAELAIGVTLGVALGELIAAGLGTGPVQIVVVILVAALLARFVDRGAMLTVQAGVQGIVIVALPVISATGGAAGRWLDALIGGGFALLVAALTPGDARRRARQLARASTSDLAQLLRLLARGVATGDEQPIRDALIAGRATQGVLDEWSEVVRNARQSVRISPASRHYQPELADLQHANLFADRAMRNARVIARRGVTAMSAGGDERISAWLTRIAEGTEELGRALGSGTSTLPARETLAGVAGRLAPQRFDEAGWRLQTLVIIMRSLTVDLLQATGLSSQSATALLARDEPPPAD

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP045920_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045920_9

3041185-3041299

Orphan

Consensus_repeat	Method
CACAGGTGTGTCCACCGCTCCCGGATCC	CRISPRCasFinder

1 spacers

WYL

The CRISPR arrays of NZ_CP045920_9

>merge|NZ_CP045920|9|3041185-3041299|CRISPRCasFinder
CACAGGTGTGTCCACCGCTCCCGGATCCGTCGAGGTCGCCGCCGAGGCCGGCGAGACCGTCCGGCCCGGAACCGGCGAGACCGACACCACAGGTGTGTCCACCACTCCCGGATCC

>NZ_CP045920|9|8|3041185-3041299|CRISPRCasFinder
CACAGGTGTGTCCACCGCTCCCGGATCC	GTCGAGGTCGCCGCCGAGGCCGGCGAGACCGTCCGGCCCGGAACCGGCGAGACCGACAC
CACAGGTGTGTCCACCACTCCCGGATCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045920.1\|WP_152910005.1\|3030670_3031411_+\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|378924
NZ_CP045920.1\|WP_153878727.1\|3038391_3038979_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|273167
NZ_CP045920.1\|WP_153879287.1\|3035244_3036501_-\|PspC-domain-containing-protein	unknown	unknown	gnl\|CDD\|226951
NZ_CP045920.1\|WP_153878724.1\|3027762_3029790_-\|acyltransferase-family-protein	unknown	unknown	gnl\|CDD\|224748
NZ_CP045920.1\|WP_153878730.1\|3043241_3044801_-\|glutamine-hydrolyzing-GMP-synthase	unknown	unknown	gnl\|CDD\|234614
NZ_CP045920.1\|WP_153878729.1\|3042370_3043153_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|379263
NZ_CP045920.1\|WP_153878734.1\|3052018_3052948_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379128
NZ_CP045920.1\|WP_153878735.1\|3053036_3056099_-\|glycine--tRNA-ligase	unknown	unknown	gnl\|CDD\|237859
NZ_CP045920.1\|WP_153878731.1\|3046288_3048391_+\|phosphate-acetyltransferase	unknown	unknown	gnl\|CDD\|235537
NZ_CP045920.1\|WP_152910004.1\|3031465_3033889_-\|DNA-helicase-PcrA	unknown	unknown	gnl\|CDD\|273429
NZ_CP045920.1\|WP_153879288.1\|3045241_3046072_-\|SURF1-family-protein	unknown	unknown	gnl\|CDD\|119401
NZ_CP045920.1\|WP_153878722.1\|3024891_3026067_-\|ADP-forming-succinate--CoA-ligase-subunit-beta	unknown	unknown	gnl\|CDD\|234813
NZ_CP045920.1\|WP_152909994.1\|3049867_3050386_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|224584
NZ_CP045920.1\|WP_152909997.1\|3044832_3045231_-\|DUF3817-domain-containing-protein	unknown	unknown	gnl\|CDD\|378962
NZ_CP045920.1\|WP_153878733.1\|3050389_3051793_-\|aspartate-ammonia-lyase	unknown	unknown	gnl\|CDD\|234779
NZ_CP045920.1\|WP_153878726.1\|3034576_3035248_-\|response-regulator	unknown	unknown	gnl\|CDD\|225107
NZ_CP045920.1\|WP_153878732.1\|3048387_3049626_+\|acetate/propionate-family-kinase	unknown	unknown	gnl\|CDD\|234680
NZ_CP045920.1\|WP_153878725.1\|3034165_3034504_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045920.1\|WP_153879286.1\|3029895_3030597_-\|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|225253
NZ_CP045920.1\|WP_153878723.1\|3026207_3028070_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223745

Protein	Function_ID	Function_description	E-value
NZ_CP045920.1\|WP_152910005.1\|3030670_3031411_+\|alpha/beta-fold-hydrolase	gnl\|CDD\|378924	pfam12697, Abhydrolase_6, Alpha/beta hydrolase family. This family contains alpha/beta hydrolase enzymes of diverse specificity.	2.35205e-07
NZ_CP045920.1\|WP_153878727.1\|3038391_3038979_+\|hypothetical-protein	gnl\|CDD\|273167	TIGR00601, UV_excision_repair_protein_RAD23_homolog_A, UV excision repair protein Rad23. All proteins in this family for which functions are known are components of a multiprotein complex used for targeting nucleotide excision repair to specific parts of the genome. In humans, Rad23 complexes with the XPC protein. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair].	0.00173793
NZ_CP045920.1\|WP_153879287.1\|3035244_3036501_-\|PspC-domain-containing-protein	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	9.68899e-23
NZ_CP045920.1\|WP_153878724.1\|3027762_3029790_-\|acyltransferase-family-protein	gnl\|CDD\|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	5.19973e-63
NZ_CP045920.1\|WP_153878730.1\|3043241_3044801_-\|glutamine-hydrolyzing-GMP-synthase	gnl\|CDD\|234614	PRK00074, guaA, GMP synthase; Reviewed.	0
NZ_CP045920.1\|WP_153878729.1\|3042370_3043153_-\|SDR-family-oxidoreductase	gnl\|CDD\|379263	pfam13561, adh_short_C2, Enoyl-(Acyl carrier protein) reductase.	7.70866e-66
NZ_CP045920.1\|WP_153878735.1\|3053036_3056099_-\|glycine--tRNA-ligase	gnl\|CDD\|237859	PRK14908, PRK14908, glycine--tRNA ligase.	0
NZ_CP045920.1\|WP_153878731.1\|3046288_3048391_+\|phosphate-acetyltransferase	gnl\|CDD\|235537	PRK05632, PRK05632, phosphate acetyltransferase; Reviewed.	0
NZ_CP045920.1\|WP_152910004.1\|3031465_3033889_-\|DNA-helicase-PcrA	gnl\|CDD\|273429	TIGR01073, ATP-dependent_DNA_helicase_PcrA, ATP-dependent DNA helicase PcrA. Designed to identify pcrA members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP045920.1\|WP_153879288.1\|3045241_3046072_-\|SURF1-family-protein	gnl\|CDD\|119401	cd06662, SURF1, SURF1 superfamily. Surf1/Shy1 has been implicated in the posttranslational steps of the biogenesis of the mitochondrially-encoded Cox1 subunit of cytochrome c oxidase (complex IV). Cytochrome c oxidase (complex IV), the terminal electron-transferring complex of the respiratory chain, is an assemblage of nuclear and mitochondrially-encoded subunits. Its assembly is mediated by nuclear encoded assembly factors, one of which is Surf1/Shy1. Mutations in human Surf1 are a major cause of Leigh syndrome, a severe neurodegenerative disorder.	9.7719e-21
NZ_CP045920.1\|WP_153878722.1\|3024891_3026067_-\|ADP-forming-succinate--CoA-ligase-subunit-beta	gnl\|CDD\|234813	PRK00696, sucC, ADP-forming succinate--CoA ligase subunit beta.	0
NZ_CP045920.1\|WP_152909994.1\|3049867_3050386_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	2.55135e-13
NZ_CP045920.1\|WP_152909997.1\|3044832_3045231_-\|DUF3817-domain-containing-protein	gnl\|CDD\|378962	pfam12823, DUF3817, Domain of unknown function (DUF3817). This domain is of unknown function. It is sometimes found adjacent to pfam07690 and pfam03176 which are both transporter domains.	1.15284e-22
NZ_CP045920.1\|WP_153878733.1\|3050389_3051793_-\|aspartate-ammonia-lyase	gnl\|CDD\|234779	PRK00485, fumC, fumarate hydratase; Reviewed.	0
NZ_CP045920.1\|WP_153878726.1\|3034576_3035248_-\|response-regulator	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	3.7794e-55
NZ_CP045920.1\|WP_153878732.1\|3048387_3049626_+\|acetate/propionate-family-kinase	gnl\|CDD\|234680	PRK00180, PRK00180, acetate kinase A/propionate kinase 2; Reviewed.	0
NZ_CP045920.1\|WP_153878734.1\|3052018_3052948_+\|hypothetical-protein	gnl\|CDD\|379128	pfam13338, AbiEi_4, Transcriptional regulator, AbiEi antitoxin. AbiEi_4 is the cognate antitoxin of the type IV toxin-antitoxin 'innate immunity' bacterial abortive infection (Abi) system that protects bacteria from the spread of a phage infection. The Abi system is activated upon infection with phage to abort the cell thus preventing the spread of phage through viral replication. There are some 20 or more Abis, and they are predominantly plasmid-encoded lactococcal systems. TA, toxin-antitoxin, systems on plasmids function by killing cells that lose the plasmid upon division. AbiE phage resistance systems function as novel Type IV TAs and are widespread in bacteria and archaea. The cognate antitoxin is pfam13338.	0.000183484
NZ_CP045920.1\|WP_153879286.1\|3029895_3030597_-\|WYL-domain-containing-protein	gnl\|CDD\|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	5.06079e-47
NZ_CP045920.1\|WP_153878723.1\|3026207_3028070_-\|hypothetical-protein	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	2.04629e-53

>NZ_CP045920.1|WP_153878727.1|3038391_3038979_+|hypothetical-protein
MTSSPNATVPTNDGPNDAAGSPTAAKRRTPRAGIRSTTVVWGLLLIAGGVLVAALGLGYRLDAITFTVIVSAGLGVALLLLAILPRRAPRATVTVYEPWPTEGPGVMPAAGSGGFVAPAATGGVSGMDDAPDPLDSAPAAPAAAPTEPPTTAAQPDQSTIEFPRSGHEPPPDDATATSAGHPTGDDWWDPSAKRD
>NZ_CP045920.1|WP_153879287.1|3035244_3036501_-|PspC-domain-containing-protein
MRRPHAGRRLAGVCAGLADHLGLPVRSVRWAFVGATVALGAGALMYAWLWAVVPGGDTPGPSRLAPRLRSLRTRVSNRELVLAGALLAVAVLLLALRGNIAGGASWIIAFVLVCLGAALAWSELGRGDDAARPRSVVLARVVAGCGLAAVGVVLFAGRGRTLDLIVWAAGVGLLLVAAVAVVLAPVGLRMWQDLGSERAARARESERADIAAHLHDSVLQTLALIRSRAEDPEAVRRLARSQERQLRDWLYTDPASPEGSIARQVEAVAAEVEERYGRQIDAITVGDDVPGAGAAALVAATREALTNAVRHGAAPVSLYLEVAPAEIEVYVRDRGEGFDLEAVPADRHGVRESIVMRMRRHGGSARIRTGRGQGTEVRLAMPRAGARDPAARVGQDEAAGPGGHEHRSARGDDREGVR
>NZ_CP045920.1|WP_153878726.1|3034576_3035248_-|response-regulator
MSTTLRVVVVDDHAMVRAGLRAELAADLQVVGEADDVEGGIAATRALRPDVVLLDVHLPGGDGGGGAEVVRGCSDLGEGVRFLAVSVSDAADDVVSVVRAGARGYVTKAISGPELSDAVRRVAGGDAVFSPRLAGFVLDAFGAGGAQGASRLSEPADDELDRLSAREQEVMRLIARGYTYREVAGELFISIKTVESHVSAVLRKLQLSSRHELTRWAAMRRLL
>NZ_CP045920.1|WP_153878725.1|3034165_3034504_-|hypothetical-protein
MTLLLQILVILHMVGWAIVFGGAVVNLKKPKIATGMLHGILTAIIAGLISMGLAHAIFTDVNDMKYGIKLLIALIAGGMIIWGGRNQEKVSRGFLGAIAGLVLANIAIAVIW
>NZ_CP045920.1|WP_152910004.1|3031465_3033889_-|DNA-helicase-PcrA
MTSLFAHLPLPDQRRFDPHAQLPAIGGEDAEGSDVVHTPPEGTAQADDLLDGLNPQQRQAVAHTGGQLLIIAGAGSGKTRVLAHRIAHLLATGRARPGEILAITFTNKAAAEMRERVAELVGPRAKSMWVSTFHSACVRILRREAKTIGLRSSFSIYDAADAQRLMTLVCRELDLDPKRFPPKAFYHRVSDLKNDLVDPDDFARTAAENPYEQNLAAAYRRYQERLREAHALDFDDLIMSTVTMLQAFPAIAEHYRRRFRHVLVDEYQDTNHAQYVLVRELVGGPGTGSGGGDLPAAELTVVGDADQSIYAFRGATIRNIVEFEKDYPAATTILLEQNYRSTQTILSAANAVIERNPGRAKKNLWTAAGAGDKIVGYVADTEHDEAAFVAEEIDALIDAGEARAGDVAIFYRTNAQSRALEEVLVRRGLPYRVIGGTRFYERREVKDAIAYLRAVANPDDSVNLRRILNVPKRGLGERSEAMVAGHAERLRISFGAALDQLDDVLGLGTRAVTGLRAFNDMLAGFRTLAAGGASPAEVLDAILDETGYLAQLRESSDPQDATRVENLAELHAVAAEFSAADPDADLGDFLERVALVADADQLPGEEEGGMVTLMTVHTAKGLEFPIVFATGLEDGTFPHSRSLADPDELAEERRLAYVALTRARTRLYLSRAGLRTMWGAPNELPASRFIADIPADLLDWRRTESAMSTLRQLGAYDRGASSGTGYGDYGRRIAKNDPAPTPSFGSAKPRGPVPNLEIGDRVTHDSYGLGRVVQVEKPGTPNAVAHVDFGDSNIKRLLLRFSPVTKL
>NZ_CP045920.1|WP_152910005.1|3030670_3031411_+|alpha/beta-fold-hydrolase
MTTTSTPSDPTIILIPGHWLGAWAWDDVLEHLSAAGAAATAVTLPGLDEHDPERSSKTLADQAAAIEDVVTRAAGGQGVVLVAHSGANAPVTLVLDRCPELIRRVVWVDSGPVAPGSVFAPDVPEDLAELPLPPFDVLGEQAGLEGLSAEVLDRFRSRAVPEPGPVLRAPVHLTNAARLSVPTTLVCCSISSAQVLELAEAGHPVFAEVVEFEHREFVDLPTGHWPMWSRPRDLAEAIHCAATRAA
>NZ_CP045920.1|WP_153879286.1|3029895_3030597_-|WYL-domain-containing-protein
MKRAERLHALSEMLRRGGARGWTAETLAAEFGVSVRTVKRDVAALESSGAPIWSRPGPGGGYGLVAGASLPPVTLSPAQAVALLAAVAAAPDAPYADLASAGVRKIVDVLDPRTRTRAEELAQRVWVDATRSSSRAVRSALEEAMADQRVLRIRYTSGEGATTSRDVEPMLFASTNGRWYLIGWCRLRGAVRWFMVDRIERAGVTTTPCEGHTIDEVGTPPPNARPAARPSPG
>NZ_CP045920.1|WP_153878724.1|3027762_3029790_-|acyltransferase-family-protein
MAAPAVTRDRSRATRPEGRGSTGPTGSTGPTGPTGTARRGRVAGTPPTPWRIHGLDGLRAIAIIAVLVFHVRPASLRGGFIGVDVFFVISGYLITTLLLRELAKNGRIDLPAFWVRRARRLLPALVTVVVASTVLALVAGGDLLVDIGRHIVGAVTFSNNWLEIGAGSSYFDAATPNLFVNFWSLAVEEQFYLVWPVITVVLLAAVSSTRLRIGLLAAGALASALAMALLLDPDAPTRVYYGTDTHAFGLLIGAGLALALAPDGPRFFRGRAWQRWRFAGAGAGAIALVVLMMRVDGAAPFAYRGGLVLASLATAAIIAALPGGPSPLTRILEAGPLAWIGRRSYGIYMWHWPVLLIVTAVLPAATADSGAWWAGKMLAVGLTIALAAASFTWIENPVRRLGFIETLRRARAWFGARRPRGKVVTAAAGAAVLAAFVVAWATAPTQNSLERAMAEAAEYVGGAARTDAAATPDGSERVTGEITGSDISSFGDSMLYVAAPALAAELPGIDIDAESNRQWPAVAEAIDDALAAGTVRDVVIIAAGTNAGARDVALIDATLDALGPDRSVVLVNIYGSSFWVEESNDNLAAVAAARENVAVADWHQAATEHPDRLQPDQTHPDMEGMYLYSAVVQDAFGELGLDVAPEDTSAGPATDPSDEPATEPSTEPAPDATGG
>NZ_CP045920.1|WP_153878723.1|3026207_3028070_-|hypothetical-protein
MVRASGWRSRTTTSRPSPPRGRTSRWPTGTRRPPSTPIGSSRIRPTRTWRACTCIPRWCRTHSASSGWTWRPRTPRPGRPPIRPMSRPPNPLPSRHRMPRAAEAVPPRRPRRSLAFARRASPRPLGFGLPPTKGGRYEQPSRLGLRRRRRHAAHRHRDLPGDLRSGDLDLLPDHPRRGDQRDHAGPGARSVQPAPGAGRVPAGPRSHAPRRRSAPDAARALPVGAARGRRRLERPRPSGSSRAVCPPAHGSVSPSTAGTACRGHSRPVQRRRRACVRSRSGRPRVGLIGTGGISAAHIAGWQVLGSDLTLYSRSGARAAAERVGARAAATVGELIEGSDIVGILTPPATHREYALAALAAGRHVVCEKPLGRTVAEAIDIAAAAATSAGVLFPAHVVRYFPAYAEARARVAAGEIGEVLATRFLRAGTAPPAGGWFYDEAASGGIIMDQLVHDLDQARWFAGEVTEVYARRATGATGTASGSGEPPAPVHTAAVTLTHASGATSQVTGYWGPPGLEFTTGFDLHGTTAALRHSTLDARSLTLDPTGTGEAAYIPAGDPADSPFTAQLRDLLAAIDGAPARVEPFDGVVSVAIAQAALESVRTRGPVAVDERELRSAVHTR
>NZ_CP045920.1|WP_153878722.1|3024891_3026067_-|ADP-forming-succinate--CoA-ligase-subunit-beta
MDLFEYQARDVFEKHGVPVLRGIVATTPEEAKSAAAELLPPDGGVVVVKAQVKTGGRGKAGGVKIAKSADEAAERAGEILGMDIKGHTVHRVMIAEGADIAEEYYFSVLLDRAERRYLAMCSVEGGMEIEQLAVERPEALAKVAIDPNVGIDAAKADEIVAAAGFDAETAPKVAAAIVKLWGVYAAEDATLVEVNPLVKTGAGEIIALDGKVTLDDNAEFRQPEHAGLEDSAAADPLEAKAAEAGLNYVKLDGAVGVIGNGAGLVMSTLDVVAYAGEKHGGVKPANFLDIGGGASASVMAAGLDVILGDPQVKSVFVNVFGGITACDQVASGIVQALEILGDAATKPLVVRLDGNSVDAGRAILADANHPLVTLVDTMDGAADKAAELANA
>NZ_CP045920.1|WP_153878729.1|3042370_3043153_-|SDR-family-oxidoreductase
MDASRFAGRTAVVTGAAHGIGAATARRLTAEGARVVLADVDVGAARDVAADLPGAVVVECDMTETATVDCALIDAVAAVGALDFLVNVAGAARRGPSVAEGMTDEDWNWAVDLNLGGAMRLVRAGVPYLGDSGAIVFVSSVNGLAAFGEDAYSAAKAGLVSFARNLAAELGPRGIRANVVAPGTVRTRVWDEVGGPDPLIPLYPLGRLGEPEDIAAAIAFLLSEDASWITGITLPVDGGVLTGPRRTMDALRAEDAEGRS
>NZ_CP045920.1|WP_153878730.1|3043241_3044801_-|glutamine-hydrolyzing-GMP-synthase
MTAALPRPVLVVDFGAQYAQLIARRVREARVYSEVVPHTLSAEAILARDPAAIILSGGPASVYAEGAPGIDPALFEAGVPVLGICYGFQTMAAALGGTVTETGRREYGRTEVTVAEPGTLLEGSPACPLAWMSHGDAVTRAPDGFEVLASSEGAPVAAFEDRERRLFGVQWHPEVLHSEAGQATLENFLYRGAGLSPDWTAANVIAEQVAAIRAQVGDAKVICGLSGGVDSSVAAALVQRAVGDQLTCVFVDHGLLRTGEAEQVEQDFVAATGVKLMVRDASDTFLDALAGVTDPETKRKIIGREFIRAFEAAARDLVSGGEDVKFLVQGTLYPDVVESGGGEGAANIKSHHNVGGLPDDLQFSLVEPLRQLFKDEVRQVGLELGVPDGIVWRQPFPGPGLGIRIVGEVTREGLTTLRAADAIVRAELTKAGLDREIWQCPVVLLADVRSVGVQGDGRTYGHPIVLRPVSSEDAMTADWSRLPYDLLAQISNRITNEVPDVNRVVLDVTSKPPGTIEWE
>NZ_CP045920.1|WP_152909997.1|3044832_3045231_-|DUF3817-domain-containing-protein
MTSPVSDPADVTRIAEQKDRSAFARYRVMAFVTGGMLLLLCLEMVLKYVFHAAGLDEQGSAKPVIGAWVPFIHGWIYVVYLIAVFDLWSRMKWSVGRILALVAGGVVPVLSFVMETRTSHWVNTTLEARRPA
>NZ_CP045920.1|WP_153879288.1|3045241_3046072_-|SURF1-family-protein
MLVLLVVILAAAAVCVRLGAWQLDRAVARAEQGQAAELAAREQAAPVPIGDIAEPQTHFTQEMVGRRVHVAGTYIGPEFFVPGQFRVDPADPENTDLWTSGYWVLSGLRTDGGAVLPVVRGWVAETDPAYLNAEGTRVEAIGYLDGSQAVGDPVDGDEIGAVSSAQLVNEWSTPIYSGFIVLAESDPAVPDPAGLPPLDDVAVPTLSGGGLNLQNLAYAGEWFIFGGFAVLIWWRMVRDEARDLAAAAAAADDDAGAAGPPEAARDPLVVTPPARP
>NZ_CP045920.1|WP_153878731.1|3046288_3048391_+|phosphate-acetyltransferase
MSARSIYVASPEGHTGKSSIALGIVDLLVGQVRRVGVFRPVIRSRSEPDAVLSLLLRHVGVDLPYEDCTGVTYDEIHADPEAALGRIISRYRDVAHRCDVVVIVGSDYTDVAGPTELAYNTRIAANLGSAVVLVTSAWQRAGSDVRHVVDVAMAELAAGHAQVVAVVASRAVPEHLEDVRAALADLPVPSWALPDVPLLSAPSARELMDAVDGALWAGDDALLDREVENVIVGGMTMDHILDRLTDGAMVIVPGDRSEVVLSIVAAHAAESFPSLAALMLNGGYLPSEQVTRLVQGLGQRLPIVTTGHGTFETASRAAATPGLMGTGSQRKIDVARSTFEAHVDGARLRAAVAVPRASVVTPLMFEYDLIERARASRKHVVLPEGGDERILRAASTLLARDVVDLTLLGDEQAIRARATELGLDLSGAQVLSPTEPELRERFAQEYARLRAHRGMTVDRAREVVTDVSYFGTMMVQLGLADGMVSGAAHTTAHTIKPAFEIIKTSPGTQVVSSVFFMCLPDQVLVYGDCAVNPDPNAAQLADIALSSAETAAQFGVDPRVAMLSYSTGTSGFGADVDKVREATDLARERAGALSIEGPIQYDAAVDASVAATKLPGSDVAGKATVFIFPDLNTGNNTYKAVQRSAGAVAVGPVLQGLRKPVNDLSRGALVQDIVNTVAITAIQAQGLDTAAGTIGEGGPR
>NZ_CP045920.1|WP_153878732.1|3048387_3049626_+|acetate/propionate-family-kinase
MTNVLVINSGSSSLKYQVVDATTGIAAATGLIERIGLVGGRLIHERGAAGRSGAETTEWQIDAADHTVAVEQMQRAFTELGPDLADMDLAAIGHRVVQGGARFGGPVLVTEEVKQIIDGLADLAPLHNPPNLAGIEAAQRAFPDLDHVVVFDTAFHLSMPARASTYALNAAVARQYRIRRYGFHGTSHSYVARQAAQFLGKRDSDTNVIVLHLGNGASATAVAGGTSIDTSMGLTPLEGLVMGTRTGDIDPAVALYLSRHAGMGIDEIDDLFNRRSGMLGVTGHQDMRDVIEAWEAGNPDAELGLDLYTYRLRKYLGSYLAVLGRVDAVVFTAGIGENSPDIRLRTMSGLDHLGMGIDPARNLERKPGVRDISAESARVRTLVIPTNEEWEIARQTMEVVLAPGEHEPRALP
>NZ_CP045920.1|WP_152909994.1|3049867_3050386_+|GNAT-family-N-acetyltransferase
MTETDQRQGRRDRVAIELRDVWDDDLPTFNEYLRDPQSQAMASSTFVDYTDTQGFNSYWSKLRSNEEATVRTITLAGRPHEVVGHIAVSPGGKGLQVSYWIDREHWGQGIATSALRAMLAEVAERPIFANVTRINEPGAAVLQRNGFNRAGNDSGFDAGKGRMIDDVIFRLG
>NZ_CP045920.1|WP_153878733.1|3050389_3051793_-|aspartate-ammonia-lyase
MSDETQYRIEHDTMGEVRVPIGAKYRAQTQRAVENFPISGRGISRHHIAALAHVKRAAARANNELGYLDDARAAAIMAAADRVIAGEFDDHFPIDVFQTGSGTSSNMNMNEVIATLADESGLAGDRAVHPNDHVNASQSSNDVFPSSIHIAATEAVTSELLPALELLATSLEAKRDEFADVVKAGRTHLMDATPVTLGQEFGGYAQQIRYGIERVASALPRVAELPLGGTAVGTGITTPIGFPQRVISLIAENTGLPLTEAADHFEAQSARDGLVELSGQLRTIAVSLTKICNDLRWMSSGPRTGLGEIHIPDLQPGSSIMPGKVNPVVPEAVLMVCAQVVGNDAAVAFGGSSGSFELNVMMPMMARNVLESITLIANSTRVLATKTVDGIAANADRARELAESSPSIVTPLNRIIGYEAAATIAKHSIAANLTIRQAALDLGYVERGDLTEAQLDEALDLMSMTHP
>NZ_CP045920.1|WP_153878734.1|3052018_3052948_+|hypothetical-protein
MVRQLDILAAAARRQAGLVSRRQLLAYGITKRQIETRTRRGEWHRVTTGVYDLRAGSESVDRFDHARLRSAWTGLLATDPHGIAAGACALALLGAWGLPTSLRPEVCLPGAMHTPGAAGVTVRRFSKPLELVELHGRRLASPVTALIQAVPEWPRDVVVAVLDSALNRGLIAAVDLERIRTGVRGRRGAAQLHPWWPLVDGRAGSPVETKARLQCLDAGLPPPRLQVPILDATGWPMAFADLGWLRTDGIWVVVEIDGRSIHTRPEALFRDRARQNAIAQAGGYLLLRFTAKDVRERRIANEVAHALRR
>NZ_CP045920.1|WP_153878735.1|3053036_3056099_-|glycine--tRNA-ligase
MLTVQDALLTLQQFWTDRGCLVTQPFNTEVGAGTMNPATILRVLGPEPWHVAYVEPSVRPDDARYGQNPNRLQQHTQFQVILKPDPGNPQELYLDSLRALGIDVDAHDVRFVEDNWAQPAIGAWGLGWEVWLDGLEITQFTYFQQVGGQNLDPVSVEITYGVERIMMALQGVTHFKDMVYAEGVSYGEIFAQGEYEMSRYYLDDADVATNQELFARYIGEAERMIEARLPVPAHTYVLKSSHAFNVLDSRGAISTTERAQAFSTMRRLAREVSALWVARREELGFPLLDGAAPGLRNDSVMPPAAGEPMDGDELASRSEALRGAAPELLAIEIGVEELPPHVLDQAIEQVREGLTSRLAASRLEHGPIVVAGTPRRIVARVAAVASYEPDADELRKGPKVSAAYDADGNPTKPALGFARGQGVEAEELERADFGGTEHVVVRRSRPGRSVLEVVADALGEIVTGLRADKNMRWGDPELSYSRPIRWLVALWGGEVVPTHASGVHSGRTTYLGRTDAAPLVRIETAADLERVLTGRGFVLEPERRRAIVLEQATALAAGVGGLIDAGAEAGLLDEITNLVEAPHGILGEYEARYLELPEEILTTVMRKHQRYLPVRSVDGALLPYFVAIANGECDEDAVRVGNENVLRARYEDAAFFYDADREVAPEVFRGRLERLTFENRLGSVAARADRIRDGAANLATVLDGLDAPLSEADQRTLVEAGRLAKFDLATQMVVELSSLAGVMARDYALKAGQSPEVATALFEMELPRSAGDALPTSVPGALLSLADRFDLLVAMFAIGAKPTGSSDPFALRRAALGVVSVLRMHPALEELGIEFGVGIAAARLEEQGIEVSPEARAAVVEFVTGRFEQQLRDEGVSAEHVAVITPMTNEPFRAQAVLDQLPAARAVEGFGGLVEQVQRITRIVPQGTEGAFDRSVLTDAAELALADAVADLTDFSRAPLPEWARASVDSVGLLTRFFDEVLVMAEDDALKAARLGLLQTIVDRAPSGIDWRALDHALDG

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP045920_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045920_10

3231522-3231654

Orphan

Consensus_repeat	Method
TCCGGGAGCGGTGGACACACCTGTGCTGTCGGTCCCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045920_10

>merge|NZ_CP045920|10|3231522-3231654|CRISPRCasFinder
TCCGGGAGCGGTGGACACACCTGTGCTGTCGGTCCCGCTGGTCCCGTCGGTTCCGGGCCGTACGGTCTCGCCGGCCTCGGCGGCGACTACGGTGGTTCCGGGAGCAGTGGACACACCTGTGCTGTCGGTCCCG

>NZ_CP045920|10|9|3231522-3231654|CRISPRCasFinder
TCCGGGAGCGGTGGACACACCTGTGCTGTCGGTCCCG	CTGGTCCCGTCGGTTCCGGGCCGTACGGTCTCGCCGGCCTCGGCGGCGACTACGGTGGT
TCCGGGAGCAGTGGACACACCTGTGCTGTCGGTCCCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045920.1\|WP_153879296.1\|3240167_3241970_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|223651
NZ_CP045920.1\|WP_152909667.1\|3228888_3230310_-\|DNA-repair-protein-RadA	unknown	unknown	gnl\|CDD\|236994
NZ_CP045920.1\|WP_152909661.1\|3237685_3238261_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045920.1\|WP_153878831.1\|3222320_3223433_-\|4Fe-4S-dicluster-domain-containing-protein	unknown	unknown	gnl\|CDD\|319882
NZ_CP045920.1\|WP_153878834.1\|3235934_3236612_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045920.1\|WP_152909659.1\|3238579_3239137_-\|amino-acid-N-acetyltransferase	unknown	unknown	gnl\|CDD\|236132
NZ_CP045920.1\|WP_153878825.1\|3217490_3218945_-\|L-seryl-tRNA(Sec)-selenium-transferase	unknown	unknown	gnl\|CDD\|235278
NZ_CP045920.1\|WP_152909658.1\|3239154_3240129_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|225263
NZ_CP045920.1\|WP_153879295.1\|3227183_3228854_+\|peptidase-M3	unknown	unknown	gnl\|CDD\|341050
NZ_CP045920.1\|WP_153878827.1\|3219448_3220474_+\|selenide,-water-dikinase-SelD	unknown	unknown	gnl\|CDD\|273100
NZ_CP045920.1\|WP_153878835.1\|3236646_3237684_+\|A/G-specific-adenine-glycosylase	unknown	unknown	gnl\|CDD\|224115
NZ_CP045920.1\|WP_153878828.1\|3220531_3220765_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045920.1\|WP_153878829.1\|3220770_3221040_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045920.1\|WP_152909664.1\|3234845_3235931_+\|DNA-integrity-scanning-protein-DisA	unknown	unknown	gnl\|CDD\|237395
NZ_CP045920.1\|WP_152909656.1\|3242057_3242807_+\|aquaporin-family-protein	unknown	unknown	gnl\|CDD\|223653
NZ_CP045920.1\|WP_153878826.1\|3219090_3219330_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045920.1\|WP_152909660.1\|3238257_3238503_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045920.1\|WP_153878832.1\|3223432_3226666_-\|formate-dehydrogenase-N-subunit-alpha	unknown	unknown	gnl\|CDD\|273689
NZ_CP045920.1\|WP_153878833.1\|3233911_3234778_-\|3-methyladenine-DNA-glycosylase	unknown	unknown	unknown
NZ_CP045920.1\|WP_153878830.1\|3221211_3222324_-\|nitrite-reductase	unknown	unknown	gnl\|CDD\|309148

Protein	Function_ID	Function_description	E-value
NZ_CP045920.1\|WP_153879296.1\|3240167_3241970_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|223651	COG0578, GlpA, Glycerol-3-phosphate dehydrogenase [Energy production and conversion].	2.81482e-153
NZ_CP045920.1\|WP_152909667.1\|3228888_3230310_-\|DNA-repair-protein-RadA	gnl\|CDD\|236994	PRK11823, PRK11823, DNA repair protein RadA; Provisional.	0
NZ_CP045920.1\|WP_153878831.1\|3222320_3223433_-\|4Fe-4S-dicluster-domain-containing-protein	gnl\|CDD\|319882	cd10560, FDH-O_like, beta subunit of formate dehydrogenase O (FDH-O) and similar proteins. This subfamily includes beta subunit of formate dehydrogenase family O (FDH-O), which is highly homologous to formate dehydrogenase N (FDH-N), a member of the DMSO reductase family. In E. coli three formate dehydrogenases are synthesized that are capable of oxidizing formate; Fdh-H, couples formate disproportionation to hydrogen and CO2, and is part of the cytoplasmically oriented formate hydrogenlyase complex, while FDH-N and FDH-O indicate their respective induction after growth with nitrate and oxygen. Little is known about FDH-O, although it shows formate oxidase activity during aerobic growth and is also synthesized during nitrate respiration, similar to FDH-N.	6.46274e-85
NZ_CP045920.1\|WP_152909656.1\|3242057_3242807_+\|aquaporin-family-protein	gnl\|CDD\|223653	COG0580, GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism].	1.45479e-57
NZ_CP045920.1\|WP_152909659.1\|3238579_3239137_-\|amino-acid-N-acetyltransferase	gnl\|CDD\|236132	PRK07922, PRK07922, amino-acid N-acetyltransferase.	1.43243e-93
NZ_CP045920.1\|WP_153878825.1\|3217490_3218945_-\|L-seryl-tRNA(Sec)-selenium-transferase	gnl\|CDD\|235278	PRK04311, PRK04311, selenocysteine synthase; Provisional.	0
NZ_CP045920.1\|WP_153879295.1\|3227183_3228854_+\|peptidase-M3	gnl\|CDD\|341050	cd06455, M3A_TOP, Peptidase M3 thimet oligopeptidase (TOP), also includes neurolysin. Peptidase M3 Thimet oligopeptidase (TOP; PZ-peptidase; endo-oligopeptidase A; endopeptidase 24.15; soluble metallo-endopeptidase; EC 3.4.24.15) family also includes neurolysin (endopeptidase 24.16, microsomal endopeptidase, mitochondrial oligopeptidase M, neurotensin endopeptidase, soluble angiotensin II-binding protein, thimet oligopeptidase II) which hydrolyzes oligopeptides such as neurotensin, bradykinin and dynorphin A. TOP and neurolysin are neuropeptidases expressed abundantly in the testis, but are also found in the liver, lung and kidney. They are involved in the metabolism of neuropeptides under 20 amino acid residues long and cleave most bioactive peptides at the same sites, but recognize different positions on some naturally occurring and synthetic peptides; they cleave at distinct sites on the 13-residue bioactive peptide neurotensin, which modulates central dopaminergic and cholinergic circuits. TOP has been shown to degrade peptides released by the proteasome, limiting the extent of antigen presentation by major histocompatibility complex class I molecules, and has been associated with amyloid protein precursor processing.	0
NZ_CP045920.1\|WP_153878827.1\|3219448_3220474_+\|selenide,-water-dikinase-SelD	gnl\|CDD\|273100	TIGR00476, selenide_water_dikinase, selenium donor protein. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements: SelC is the tRNA itself, SelD acts as a donor of reduced selenium, SelA modifies a serine residue on SelC into selenocysteine, and SelB is a selenocysteine-specific translation elongation factor. 3-prime or 5-prime non-coding elements of mRNA have been found as probable structures for directing selenocysteine incorporation. This model describes SelD, known as selenophosphate synthetase, selenium donor protein, and selenide,water dikinase. SelD provides reduced selenium for the selenium transferase SelA. This protein itself contains selenocysteine in many species; any sequence scoring well but not aligning to the beginning of the model is likely to have a selenocysteine residue incorrectly interpreted as a stop codon upstream of the given sequence. The SelD protein also provides selenophosphate for the enzyme tRNA 2-selenouridine synthase, which catalyzes a tRNA base modification. It also contributes to selenium incorporation by selenium-dependent molybdenum hydroxylases (SDMH), in genomes with the marker TIGR03309. All genomes with SelD should make selenocysteine, selenouridine, SDMH, or some combination.	1.16119e-136
NZ_CP045920.1\|WP_153878835.1\|3236646_3237684_+\|A/G-specific-adenine-glycosylase	gnl\|CDD\|224115	COG1194, MutY, A/G-specific DNA glycosylase [DNA replication, recombination, and repair].	1.1372e-75
NZ_CP045920.1\|WP_152909658.1\|3239154_3240129_-\|transcriptional-regulator	gnl\|CDD\|225263	COG2390, DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription].	2.54361e-80
NZ_CP045920.1\|WP_152909664.1\|3234845_3235931_+\|DNA-integrity-scanning-protein-DisA	gnl\|CDD\|237395	PRK13482, PRK13482, DNA integrity scanning protein DisA; Provisional.	0
NZ_CP045920.1\|WP_153878832.1\|3223432_3226666_-\|formate-dehydrogenase-N-subunit-alpha	gnl\|CDD\|273689	TIGR01553, Formate_dehydrogenase_major_subunit, formate dehydrogenase-N alpha subunit. This model describes a subset of formate dehydrogenase alpha chains found mainly in proteobacteria but also in Aquifex. The alpha chain contains domains for molybdopterin dinucleotide binding and molybdopterin oxidoreductase (pfam01568 and pfam00384, respectively). The holo-enzyme also contains beta and gamma subunits of 32 and 20 kDa. The enzyme catalyzes the oxidation of formate (produced from pyruvate during anaerobic growth) to carbon dioxide with the concomitant release of two electrons and two protons. The electrons are utilized mainly in the nitrate respiration by nitrate reductase. In E. coli and Salmonella, there are two forms of the formate dehydrogenase, one induced by nitrate which is strictly anaerobic (fdn), and one incuced during the transition from aerobic to anaerobic growth (fdo). This subunit is one of only three proteins in E. coli which contain selenocysteine. This model is well-defined, with a large, unpopulated trusted/noise gap. [Energy metabolism, Anaerobic, Energy metabolism, Electron transport].	0
NZ_CP045920.1\|WP_153878830.1\|3221211_3222324_-\|nitrite-reductase	gnl\|CDD\|309148	pfam03916, NrfD, Polysulphide reductase, NrfD. NrfD is an integral transmembrane protein with loops in both the periplasm and the cytoplasm. NrfD is thought to participate in the transfer of electrons, from the quinone pool into the terminal components of the Nrf pathway.	1.43482e-15

>NZ_CP045920.1|WP_152909667.1|3228888_3230310_-|DNA-repair-protein-RadA
MSSKSTKSATASATRPQFQCSECGWTTSKWVGRCGECQAWGTVAETDGPSSARTASVVPTLAAAALPIGEVDANLARFRSTGVSEVDRVLGGGIVPGAVMLLAGEPGVGKSTLLLDVAARCAGTGRRVLYVTAEESAAQVRLRADRIDAVHERLLLAAETDLGKVLGQIEATQPELLVVDSVQTLASAQVDGSAGGVAQVREVAASLIGVAKRTNMPVILVGHVTKDGSIAGPRVLEHLVDVVCQFEGDKHAQLRMLRAVKNRYGATDEVGCFVMNESGIHGLADPSGLFISGRRSGVTGSCVTVTLDGRRPLPIEIQALLSHSSTPQPRRATHGVDGSRVAMTLAVLATRSMKPVAGLDVYVSCVGGARAHEPGADLAVALAVASSQDNEPLPEGLVALGEVSLTGELRPVLGTGRRIAEARRLGFTRALVPVGSDLGGAQLAGIRVKEIAHLDDALKYTGLSAGYRGPRRV
>NZ_CP045920.1|WP_153879295.1|3227183_3228854_+|peptidase-M3
MDPVARRLLERVRRDFRRGGVGLAGPERTRIAAISEHLVSAGQEFARNIREDTRSIRVHPDRLAGLPPDWIADHPAEADGLVSVTTDYPDSVPFFMFAQDAEARRDLRLAYLNRAWPVNEEVLGRILALRREQAHLLGYASWADYDAEVKMIGSGPAIADFIGAIAAAALEPGRRDRDVVLERLRRDDPAATGVGIADAAFYTELVRRERFGVDAQEVRAYFDFERVRAGLLEVTGRLFGVEYRPVPDAPIWHEDVTCYDVYERDGAAGADGRAGAVGDPRLLGRIYLDLHPREGKFSHAAQFELVSGVAGRQLPEGVLGCNFGRGLLDHDDVVTLFHEFGHLLHHVFAGHGRWVEFSGVATEWDFVEAPSQLLEEWAWDARVLATFARNAAGETIPAELVARMRAADDFGQGLDARTQMFYAALSYSLHTEQVADLTAHTARLQGEYSLFEYLPGTHQAASFGHLDDYSSGYYTYMWSLVIAKDLFSAFAGEDGENGRGGAGHGGTGGADLFDPATARRYRETVLAPGGSKDAADLVADFLGRPYSFAPFERWLA
>NZ_CP045920.1|WP_153878832.1|3223432_3226666_-|formate-dehydrogenase-N-subunit-alpha
MARWSPLEWPVFRQARSGDVLGRGAAVTSAATRGTRARTATADRVVQSVCPYCAVGCGQRVFVKNEKVIQIEGDPDSPISRGRLCPKGAASEQLVNSPGRQTEVLYRAPGAAEWTRLDRDTALDMIADRFLASRRNTWQERDPQGRILRRTMGIAALGGATLDNEENYLIKKLFTAAGAIQIENQARIUHSATVPGLGTSFGRGGATQYLQDLAHADCIVIQGSNMAECHPVGFQWVAEAQARGARVIHVDPRFTRTSALADKHLPIRAGSDVVLLGAVINRVLTDESYFREYVTAYTNASTILREDFRDAEDLDGLFSGYDARTGSYDNATWAYATDPETGAELHDPTLTDPRCVFQVLRRHYSRYTPEAVEASCGIGPADFDYLARAVIENSGRERTTAFVYAVGWTQHTLGAQFIRTAAILQLLLGNMGRPGGGIMALRGHASIQGSTDIPTLFDMLPGYLPMPLAGRHDTFADYTASFAAKDQKGFWANGDAYAVSLLKAWWGESATAGNDWAYDYVPRLTGPHGTYQTVAAMLADEVEGYFLLGQNPAVGSSNGRMQRMAMSHLKWLVVRDLNMIESATFWRDSPEIETGELRTGDIDTEVFFLPAASHVEKAGSFTQTQRLLQWRHKAVAPPGECMSELEFFHQLGKRLRDRLAGSTDERDRPLLELTWDYPADADGEIDSGAVLAEINGWHVDPAAEAGSKRRYLSTFNEMRADGSTVGGCWIYTGVYAGGVNQAARRKPGDQQPTTALEWGWAWPSNRRILYNRASADPQGRPWSERKKYVWWDEAAGRWTGVDVPDFIPDRAPGATGDPDDPAAGGPGAIAGDDAFIMKPDGKGWLFAPTGVVDGPLPTHYEPQESPVANALYTQQRNPGRVTFPHKDNLSAPSADEPGAGVYPFVFTTYRLTEHHTAGGMSRTLPYLSELQPEMFCEVSPELAALRGLTNEGWATIVSARAAIEARVLVTRRLRPLQVAGRTVHQVGLPYHWGVGGDAIVSGDAANDLLGITLDPNVLIQESKAATCDIVPGRRPRGAALLRLVSEYQSRAGATTHTGNEPLGGPGEPPTEPREGGA
>NZ_CP045920.1|WP_153878831.1|3222320_3223433_-|4Fe-4S-dicluster-domain-containing-protein
MGQLFGHTDPAPDAGWTDAGPRKGFFTDTSICIGCKACEVACKEWNQLPAAGAGEGGGLLGSSYDNTGALGADTWRHVAFIEQDSGRIAAARESGRRLVDLGMPTLSPAAGGSMDGARSPRVDALAAAGASDGIGAPGGAGAHAGLDVLGGTEGSAHPDTPEFRWLMASDVCKHCTHAACLDVCPTGALFRSEFGSVVVQDDVCNGCGACVAACPFGVIERRADGVSEPARQRPQAEAVGHSQGGIAQKCTLCYDRLTEGEQPACAQTCPTESIRFGERDELVERARRRVGQLHSQGMTEARLYGANENDGVGGTGSVFLLLDEPEAYGLPPDPRVCTADLPGMYARAGLAAAGMLAAAALAFARRGGRA
>NZ_CP045920.1|WP_153878830.1|3221211_3222324_-|nitrite-reductase
MTASEFAGYRPPDEPRRRRRRDGARPGSGRGRGPRRPGGADGSREMPVVPDAEFTSYYGRPIVKPAPWGGDIAAYLFLGGLAAGSGLLAAGAQLTGRPALRRVGRFAAIGSAGLGTVTLIRDLGRPERFANMLRTIKVTSPMSVGSWLLAGFATSAGVAAAGEVDRMSAGRLPLGPLRPLLRQADGAAGIVAGALAPGLAAYTGVLLSATATPTWNEARDELPFLFAGSAALAAGGLAMIATPRAEAGPARGLALAGVAADLAASGVMERRVDPAIAETLRGGRAGEMLRASQALAVTGGIGTLLAGRSRTAAVCSGAALLAASVLTRFGIFEAGMSSARDPRYTVEPQKRRLERRRAAGITDDSITTAE
>NZ_CP045920.1|WP_153878829.1|3220770_3221040_+|hypothetical-protein
MTRRSLEEIKARANKFADAFESYDPEPGHEGAPLPPVMAVKLAAWRRDVAERDLAEAVRIAREQRLSWREVGDAIGTSGEAARQRYTNA
>NZ_CP045920.1|WP_153878828.1|3220531_3220765_+|hypothetical-protein
MESELIILEPAHRHGVQDAAMLHALRYPVRHFVQDDGMTMFIGPDETGTLVEVGVIEWNGIIAVAHAMRPARPKFLR
>NZ_CP045920.1|WP_153878827.1|3219448_3220474_+|selenide,-water-dikinase-SelD
MEISPETLGAGQSDTTAALRLTDFAHGGGCACKIPPGELEEAVRALAGQDERGVLVGLDDGDDAAAVLVAPDLAVLSTADFFTPVVDGARAWGMIAAANALSDIYAMGGRPVVAINLVGWPRERLPMELLSEVLAGGLEIAQRAGCPLIGGHSIDDPEPKYGLAVTGVADPDRLLRIDAATPGLPITLTKPIGVGILNNRHKATGESFPEAIASMTALNREASEAAIGAGARAATDVTGFGLLGHLHKLCRASGVGAVIEAGAVPVLPGVRSSLAAGYVSGGTRRNLDWVREHLRVGPGVSEEDLLLLADAQTSGGLLVVGELPGHPVIGHTVAGAGIEIR
>NZ_CP045920.1|WP_153878826.1|3219090_3219330_-|hypothetical-protein
MDRHLGRADHPRQSYLPRGISPRLCERSGGDVDGAGEFATADVINASVVLLSRAVEGVLVTSDPDDMRRLDPAIDLALC
>NZ_CP045920.1|WP_153878825.1|3217490_3218945_-|L-seryl-tRNA(Sec)-selenium-transferase
MLPGCEGGTVPDPRRGIPRTDALLALPAARAAADRLGPNRVRTAVRASQEAARRGELAPEAVEADTLARIAGLESREASSLRPVLNATGVVVHTNLGRAPLSDAARAAVAAASGYTDLELDLRTGRRSRRGEGARAALLAACPAAGDALVVNNGAAALLLAVTALAAGRDVIISRGELVEIGGGFRLPELLTATGARLREVGTTNRTHARDYSGALGAETGCLLKVHPSNFTQAGFVTDVPLTELRGIASEGGVPLVADLGSGLLHPEPVLPGEPDVTSALAAGADLVIVSGDKLLGGPQAGILLGRVDLIDRLARHPLARALRADKLTLAALEATVIALTAMPGPAAATPVMSAVRADPQRLRDRAEALAAALPASLAATVVPHDGRVGGGGAPGVALQGWAVRLPERLARTLRANDPAVLARTHDGACLLDLRCIPEADDDVLQRVVRAALAAPEVLPAPAPDLPTGPSTELPHVPAGGEAR
>NZ_CP045920.1|WP_153878833.1|3233911_3234778_-|3-methyladenine-DNA-glycosylase
MSTILDREQWPARERAHEARIDDLTRGHRERAGRGEPHPVEDFLFHYYRNPLGHLRRWHPGARFVLAGAEERAGRRFYRMDDDAHLGVDVASFAAEREGVIARARLVLARTASRSAQLACFGLHEWAMVYRAGERPEAVRHPWPLRLGVGGTEDVVESHTIRCTHYDAYRFFTEPAAPRNTVTPTRERQPALEQPGCLHAGMDLYRWAFKLVPVVPSELVADCFDLARRIRVLDMRASPYDLRDLGYEPVAIETPTGKAVYVAAQREFAAEGAGLRARLLAELDHAGL
>NZ_CP045920.1|WP_152909664.1|3234845_3235931_+|DNA-integrity-scanning-protein-DisA
MAVSESALAPLLRETLASVAPGTELRDGLERILRGRTGALVVLGFNDVVEAMSTGGFHLDVGFSSTRLRELAKMDGAIVLDPGRNRILRAAVQLLPDSAIETSESGTRHRTAERAAKQTGLPVISVSASMRIVALYVGHQRYVLEDSDTILGRANQALATLERYKIRLDEVSGALSALEIEDLVTVRDVAAVAQRLEMVRRISVEIGDYVVELGTNGRLLALQFDEMITGIGPGLELVVRDYVDSRSARSESGVLADLAALDSAQLIDLTQIARVLGLGGRQGEALDSAIAPRGYRMLMGIPRLPTSVVTAVVAHFGTLQKMLAASIDDLETVDGIGAQRARAVREGLSRQAESSLLERFV
>NZ_CP045920.1|WP_153878834.1|3235934_3236612_-|hypothetical-protein
MSGSGRRTPPTSARGGAPSGRPDAATFRRRRLTVGLLALVLVAGLVIGGRALWGIVGGDRAGSADAGGSTPATPTGPTEEELANPVACAAGALEVSIDLTGDTLRHGAGSDFPITVTNSGQVPCLVDLGYAGLELALFSGGDRVWTTADCHGERPEHQEYLFDLGYSQTTTIPWQGRRSAPDCAKDQNFADAGTYRARVTLHPVSRGEDAGPAAPITQTRVFGLE
>NZ_CP045920.1|WP_153878835.1|3236646_3237684_+|A/G-specific-adenine-glycosylase
MSDTGHVSEPTAPLRPPHPARPPRPPHRTDRTDRAGVAAPDPATPAASSALVRALTDWFDAHARPLPWRSAAGVRAAGGPRADHAWGVFLSEVMSQQTPISRVEPIWREWIRAWPTPADLAAATPAEVLRSWRHLGYPRRALRLLEAAAAITRDHGGRVPAAEADLLDLPGVGAYTAAAVSAFAFGRRSVVLDTNVRRVLGRVTGGLALPRPHLRRDEQRGAAALVPADPAAAATWNAAVMEFGALVCTAAAPDCSACPLTSCAWREAGYPADVFRRRRQSWAGSDRQARGRIMAQLRESPERTAAELAAGVPAAAPAGQHERALASLLADGLVAQVAGGYRLPS
>NZ_CP045920.1|WP_152909661.1|3237685_3238261_+|hypothetical-protein
MIPTPDRPAGPERPEVPGLDEIPADVVLARGARALLQALLLSIGMVVLLALVTLAAIALAGPQRTGPMITAGQIVTAWAAALALVGAIVCGRGHLEVLRDSPDPRGVAAVLAATQRRLAWLPRLVVAGCIVAVTIWVLIDSAGFVGALVASAVAVQVPVVLGFVRRDLLAPARLAGPPQLPLRERIRRAGR
>NZ_CP045920.1|WP_152909660.1|3238257_3238503_-|hypothetical-protein
MRHAGSRYSEEPAESDSGDVTEGLGRQFELDQLKHERAERAELDEHPDASGEVTEGLGRQFELDQLRHERAQESRLKKGGN
>NZ_CP045920.1|WP_152909659.1|3238579_3239137_-|amino-acid-N-acetyltransferase
MTAPTPPRGHDGSVEQTRRAADVAIRPAMPADVPAIAGLVTPYAARRILLGKDLVDYYEAVQEFHVAELAGEIVGCGALHVMWRDLAEVRTLAVHERMRGTGVGHRLLVRLMDRARELDLDRLFCLTFEVDFFGRHGFEVAAGEVVDPRTYAELLLSRDDGVAEFLDLARVKPNTLGNTRMIRSL
>NZ_CP045920.1|WP_152909658.1|3239154_3240129_-|transcriptional-regulator
MRDLDQAYRAATMYYLQNQKMEVIGATLGISRSTVSRLLTAARAAGIVEVSVTAPAQEVQSLGHRIAATYGVRVHVVPVRRRAGELQRLDQVAVVAAHLLQQWFTDGMLMGVAWGTTISAVARHLTPRSTRDTAVVQLNGAANTSTSGVTYATDLIGALASAFDATTYYFPVPAFFDFEQTKQLMWRERSVRKILQVHERVDLALFGVGSPEAAVPSHVYTAGYLDRTDLDQLERERVVGDVCTVLLREDGSYRDIALNARASGPTPQELRRIRRRVCVVVGETKVRALVGALNARVATDLVIDQTTAQALLDYLAEPGRPGGR
>NZ_CP045920.1|WP_153879296.1|3240167_3241970_+|FAD-dependent-oxidoreductase
MLAHLLPGDKNRSYRDLRHRRGIVASTPLTARTRTDALASMSDEHGLDVLVIGGGVTGAGIALDAASRGLRTGIVEAQDWASGTSSRSSKLVHGGLRYLEMLDFSLVHEALTERDLLLTTVAPHLVHRVPFLYPIRRRVWERAYIGTGVVLYDILASLSKRRRALPYHRHVSKTRMLEEFPALREDAAVGAVQYWDAQVDDARLVFTLVRTAAEHGALAASRTQVTALLKSAGDVVTGARVRDLETGATHDIQARTVINATGVWTEETEGLSGAEGGLQVLASKGIHLVIPKERIQGTKGLILHTEKSVLFVIPWPDYWIIGTTDTPYTQDPRNPVATKVDIDYLLDHVNAVLDRPLTHEDIAGVYAGLRPLLQPVAKADGSSTKVSREHTVASPAPGLVAIAGGKLTTYRVMAKDAVDFALGAAAATNPSITDRVPLSGADRLPSIRRTARGYARTYGWTKHMVDHLLRRYGSNLTEIVELVEARPDLATPLTHAPSYLRAEIAYAARAEMVLHLEDVLLHRTRLDYEVADGGVGAIDEILDLISPILGWDEQRRARERDAFLARRESEAAAAATSSDAEGSAARGTAGDPSPMVPLDG
>NZ_CP045920.1|WP_152909656.1|3242057_3242807_+|aquaporin-family-protein
MFTDIFVPELIGTMILILLGCGVVANYVLVGSKGTALGGGFLAINLGWGFGVTFGIYAATNSGAHLNPAVTLGFLVADDSLGMAEGMTFAKVLVYFAGQFAGAMIGAFIVWLTYKMHFDEEENKLLKLAPFSTIAEREHLGWNLIPEIVGTFVLVFSIISLKTQPAGALAPLIVGFIVLAIGLSLGGPTGYAINPARDLGPRVIHALVPIKNKGTSNFRYGLTVPIIGPVIGGILGGVLAAPLIPMLPL

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP045920_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045920_11

3365759-3365921

Orphan

Consensus_repeat	Method
GGGCTCGCCTCCGTGCGCCCGGGAGACGCCTGCTTCGCCAGT	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP045920_11

>merge|NZ_CP045920|11|3365759-3365921|PILER-CR
GGGCTCGCCTCCGCGCGCCCGGGAGACGCCTACACCTGCTGCTCCTGGCGCCCCTCGAACGGGACTCGCCTCCGTGCGCCCGGGAGACGGCTGCTTCGCCAGTCAGTTCATCGTCGACGGCCTGCTCGCCTCCGTGCGCCCGGGAGACGCCTGCTTCGCCAGT

>NZ_CP045920|11|1|3365759-3365921|PILER-CR
GGGCTCGCCTCCGCGCGCCCGGGAGACGCCTACACCTGCTGC	TCCTGGCGCCCCTCGAACGGGACTCGCCTC
CGTGCGCCCGGGAGACGGCTGCTTCGCCAGTCAGTTCATCGT	CGACGGCCTGCTCGCCTC
CGTGCGCCCGGGAGACGCCTGCTTCGCCAGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045920.1\|WP_153878916.1\|3354146_3354812_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293792
NZ_CP045920.1\|WP_153878919.1\|3357466_3358399_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP045920.1\|WP_153878925.1\|3367314_3368265_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|366180
NZ_CP045920.1\|WP_153878922.1\|3362045_3365417_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377950
NZ_CP045920.1\|WP_153878927.1\|3370773_3371769_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP045920.1\|WP_153878920.1\|3358625_3359954_-\|phosphoribosylamine--glycine-ligase	unknown	unknown	gnl\|CDD\|234856
NZ_CP045920.1\|WP_153879307.1\|3370069_3370888_+\|transposase	unknown	unknown	gnl\|CDD\|366690
NZ_CP045920.1\|WP_153878930.1\|3375413_3376445_+\|alpha-ketoacid-dehydrogenase-subunit-beta	unknown	unknown	gnl\|CDD\|223101
NZ_CP045920.1\|WP_153878921.1\|3360064_3360589_+\|OsmC-family-peroxiredoxin	unknown	unknown	gnl\|CDD\|376823
NZ_CP045920.1\|WP_152910469.1\|3360641_3361928_-\|adenylosuccinate-synthase	unknown	unknown	gnl\|CDD\|234904
NZ_CP045920.1\|WP_153878929.1\|3374382_3375417_+\|pyruvate-dehydrogenase-(acetyl-transferring)-E1-component-subunit-alpha	unknown	unknown	gnl\|CDD\|238958
NZ_CP045920.1\|WP_153878924.1\|3366869_3367166_+\|DUF503-family-protein	unknown	unknown	gnl\|CDD\|377364
NZ_CP045920.1\|WP_152910474.1\|3355262_3356192_-\|phosphoribosylaminoimidazolesuccinocarboxamide-synthase	unknown	unknown	gnl\|CDD\|237571
NZ_CP045920.1\|WP_153878918.1\|3356182_3357274_+\|DUF4237-domain-containing-protein	unknown	unknown	gnl\|CDD\|379424
NZ_CP045920.1\|WP_153878926.1\|3368759_3370460_+\|DUF222-domain-containing-protein	unknown	unknown	gnl\|CDD\|367155
NZ_CP045920.1\|WP_153878917.1\|3354836_3355172_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045920.1\|WP_153878928.1\|3373437_3374163_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|224332
NZ_CP045920.1\|WP_153876953.1\|3371901_3373227_+\|ISL3-family-transposase	unknown	unknown	gnl\|CDD\|376574
NZ_CP045920.1\|WP_153878923.1\|3366041_3366452_-\|DUF3151-family-protein	unknown	unknown	gnl\|CDD\|378646
NZ_CP045920.1\|WP_152910477.1\|3353772_3354027_-\|phosphoribosylformylglycinamidine-synthase-subunit-PurS	unknown	unknown	gnl\|CDD\|376904

Protein	Function_ID	Function_description	E-value
NZ_CP045920.1\|WP_153878916.1\|3354146_3354812_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293792	cd06262, metallo-hydrolase-like_MBL-fold, mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases which can catalyze the hydrolysis of a wide range of beta-lactam antibiotics, hydroxyacylglutathione hydrolases (also called glyoxalase II) which hydrolyze S-d-lactoylglutathione to d-lactate in the second step of the glycoxlase system, AHL lactonases which catalyze the hydrolysis and opening of the homoserine lactone rings of acyl homoserine lactones (AHLs), persulfide dioxygenase which catalyze the oxidation of glutathione persulfide to glutathione and persulfite in the mitochondria, flavodiiron proteins which catalyze the reduction of oxygen and/or nitric oxide to water or nitrous oxide respectively, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J which has both 5'-3' exoribonucleolytic and endonucleolytic activity and ribonuclease Z which catalyzes the endonucleolytic removal of the 3' extension of the majority of tRNA precursors, cyclic nucleotide phosphodiesterases which decompose cyclic adenosine and guanosine 3', 5'-monophosphate (cAMP and cGMP) respectively, insecticide hydrolases, and proteins required for natural transformation competence. The diversity of biological roles is reflected in variations in the active site metallo-chemistry, for example classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, human persulfide dioxygenase ETHE1 is a mono-iron binding member of the superfamily; Arabidopsis thaliana hydroxyacylglutathione hydrolases incorporates iron, manganese, and zinc in its dinuclear metal binding site, and flavodiiron proteins contains a diiron site.	4.37859e-30
NZ_CP045920.1\|WP_153878919.1\|3357466_3358399_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.90154e-07
NZ_CP045920.1\|WP_153878925.1\|3367314_3368265_-\|hypothetical-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	1.10931e-19
NZ_CP045920.1\|WP_153878922.1\|3362045_3365417_-\|hypothetical-protein	gnl\|CDD\|377950	pfam07971, Glyco_hydro_92, Glycosyl hydrolase family 92. Members of this family are alpha-1,2-mannosidases, enzymes which remove alpha-1,2-linked mannose residues from Man(9)(GlcNAc)(2) by hydrolysis. They are critical for the maturation of N-linked oligosaccharides and ER-associated degradation.	4.02888e-144
NZ_CP045920.1\|WP_153878927.1\|3370773_3371769_+\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	2.96357e-76
NZ_CP045920.1\|WP_153878920.1\|3358625_3359954_-\|phosphoribosylamine--glycine-ligase	gnl\|CDD\|234856	PRK00885, PRK00885, phosphoribosylamine--glycine ligase; Provisional.	0
NZ_CP045920.1\|WP_153879307.1\|3370069_3370888_+\|transposase	gnl\|CDD\|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	2.3454e-08
NZ_CP045920.1\|WP_153878930.1\|3375413_3376445_+\|alpha-ketoacid-dehydrogenase-subunit-beta	gnl\|CDD\|223101	COG0022, AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion].	1.92196e-149
NZ_CP045920.1\|WP_153878921.1\|3360064_3360589_+\|OsmC-family-peroxiredoxin	gnl\|CDD\|376823	pfam02566, OsmC, OsmC-like protein. Osmotically inducible protein C (OsmC) is a stress -induced protein found in E. Coli. This family also contains a organic hydroperoxide detoxification protein that has a novel pattern of oxidative stress regulation.	1.48905e-21
NZ_CP045920.1\|WP_152910469.1\|3360641_3361928_-\|adenylosuccinate-synthase	gnl\|CDD\|234904	PRK01117, PRK01117, adenylosuccinate synthetase; Provisional.	0
NZ_CP045920.1\|WP_153878929.1\|3374382_3375417_+\|pyruvate-dehydrogenase-(acetyl-transferring)-E1-component-subunit-alpha	gnl\|CDD\|238958	cd02000, TPP_E1_PDC_ADC_BCADC, Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain alpha-keto acid dehydrogenase/2-oxoisovalerate dehydrogenase complex (BCADC). PDC catalyzes the irreversible oxidative decarboxylation of pyruvate to produce acetyl-CoA in the bridging step between glycolysis and the citric acid cycle. ADC participates in the breakdown of acetoin while BCADC participates in the breakdown of branched chain amino acids. BCADC catalyzes the oxidative decarboxylation of 4-methyl-2-oxopentanoate, 3-methyl-2-oxopentanoate and 3-methyl-2-oxobutanoate (branched chain 2-oxo acids derived from the transamination of leucine, valine and isoleucine).	1.60337e-126
NZ_CP045920.1\|WP_153878924.1\|3366869_3367166_+\|DUF503-family-protein	gnl\|CDD\|377364	pfam04456, DUF503, Protein of unknown function (DUF503). Family of hypothetical bacterial proteins.	1.7291e-32
NZ_CP045920.1\|WP_152910474.1\|3355262_3356192_-\|phosphoribosylaminoimidazolesuccinocarboxamide-synthase	gnl\|CDD\|237571	PRK13961, PRK13961, phosphoribosylaminoimidazole-succinocarboxamide synthase; Provisional.	8.52455e-179
NZ_CP045920.1\|WP_153878918.1\|3356182_3357274_+\|DUF4237-domain-containing-protein	gnl\|CDD\|379424	pfam14021, TNT, Tuberculosis necrotizing toxin. This is the C-terminal domain secreted by Mycobacterium tuberculosis (Mtb). It induces necrosis of infected cells to evade immune responses. Mtb utilizes the protein CpnT to kill human macrophages by secreting its C-terminal domain (CTD), named tuberculosis necrotizing toxin (TNT) that induces necrosis. It acts as a NAD+ glycohydrolase which hydrolyzes the essential cellular coenzyme NAD+ in the cytosol of infected macrophages resulting in necrotic cell death. CpnT transports its toxic CTD from the cell surface of M. tuberculosis by proteolytic cleavage, where the toxin is cleaved to induce host cell death. Structural analysis determined that the TNT core contains only six beta-strands as opposed to seven found in all known NAD+-utilizing toxins, and is significantly smaller, with only two short alpha-helices and two 3/10 helices. Furthermore, the putative NAD+ binding pocket identified Q822, Y765 and R757 as residues possibly involved in NAD+-binding and hydrolysis based on similar positions of catalytic amino acids of ADP-ribosylating toxins. While glutamine 822 residue was detected to be highly conserved among TNT homologs.	8.80752e-10
NZ_CP045920.1\|WP_153878926.1\|3368759_3370460_+\|DUF222-domain-containing-protein	gnl\|CDD\|367155	pfam02720, DUF222, Domain of unknown function (DUF222). This family is often found associated to the N-terminus of the HNH endonuclease domain pfam01844. The function of this domain is uncertain. This family has been called the 13E12 repeat family.	2.27666e-23
NZ_CP045920.1\|WP_153878928.1\|3373437_3374163_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|224332	COG1414, IclR, Transcriptional regulator [Transcription].	3.04713e-35
NZ_CP045920.1\|WP_153876953.1\|3371901_3373227_+\|ISL3-family-transposase	gnl\|CDD\|376574	pfam01610, DDE_Tnp_ISL3, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS1165.	7.06175e-60
NZ_CP045920.1\|WP_153878923.1\|3366041_3366452_-\|DUF3151-family-protein	gnl\|CDD\|378646	pfam11349, DUF3151, Protein of unknown function (DUF3151). This family of proteins with unknown function appears to be restricted to Actinobacteria.	1.99951e-55
NZ_CP045920.1\|WP_152910477.1\|3353772_3354027_-\|phosphoribosylformylglycinamidine-synthase-subunit-PurS	gnl\|CDD\|376904	pfam02700, PurS, Phosphoribosylformylglycinamidine (FGAM) synthase. This family forms a component of the de novo purine biosynthesis pathway.	5.92662e-27

>NZ_CP045920.1|WP_153878922.1|3362045_3365417_-|hypothetical-protein
MGYSYSESSPPGAGIRRRGLAVIAALGLAATGVAGVVLAPATSAATVDDGDYAGLVNPFVGTEDEGNAYPGAVVPFGMVQLSPDNTSTYGSTSYSNRAGRVWGFSHRHVNSAGCPAAGEVLVTPSTTEVPITTKRFLGLKNQAETERASAGYYTALLENDVTAELTATERTGVHRYTFGEGDSGHVSINVGQTLNSTHESSITWVDDRTVEGQLTTSGFCWGTPKTTYYFSATFDRDAESVGTWGNEGGYNAGSESSEVAGGNNGAVATFDTSTDDTVELTVGVSFVDLDGARANREAEGVSGGERVSFDEAHAQAVGAWNEALGRFDVTMPDEDQLPIFYTQAYKSLLSPIIGSDVDGRYRGLDAEVHQADGWTYYQRFSLWDTYRTQATVHGLFEHDRATDIARSMYRARVEGGWLPRWSLDMVETTVMAGDPASPWVAENFALGTVPDDIAEEFWDYLVENATTAPPADVDSPGRQSAEFYLENGHIPFYFENEPGLGQEYEEYRHGGSATMEFAHSDAAIGAAAYRTGHDADADAFLERGTNWARLWNPEVSLTGGFTGVVNAVTPAGEFVSAPEKSSVQQSGFHEGTPWHYQWMVPQDVTGLIEAMGGEESFVERLDYYVNIPALRENPGASPSTWARGGSDYYSSIGYNPGNEPMLGTPWLYNYVGQPAKAGDVLASQLNRFPNTPGGGVGNDDLGTMSSWYVLASLGIYPVQPGSGIMALNAPRVEAATVTLDNGATIEIAAPGASSSEPRYISSLTVDGVDHSATWVDVSELQDGARLEFTLSESPEGLTWGTAPADRIPSVSDPLRAELELTGLVDGDLAATAGEDLTADLARAGVSVISGPAPADGAVPVEGTIEWSTGDTSPVTVAGQDGAWVLSTSARFEEAGTHEGVLTVSSGLDTPAFAPAAFEPETLRVSVVVEPADGGSDGSDSSDGSDGSDGTDGSDGSDGSDGSDGSDGSDGTDGTDGSDGSDGADGSDDSAGSDGSDGSDGSDGADGSDDSAGSDGSDGSDGSDGSDGSDGSDGSDGSDGSDGSDGTDGTDGTDSAAGADGSDGTNGGDGTDGSDGADAPDPGADPLPDTGAPVGATLLAVLALIGAGVLARAWTLRRAGVVHK
>NZ_CP045920.1|WP_152910469.1|3360641_3361928_-|adenylosuccinate-synthase
MPAVVVLGAQWGDEGKGKATDQLGSRVDYVVKFNGGNNAGHTVVVGDQKYALHLLPSGILSPGCTPVIGNGVVVDLEVLFSELEGLNSRGVDTSRLLVSSSAHVIPSYNRTLDKVTERFLGKRQIGTTGRGIGPTYADKMNRVGIRISDIFDEGILREKVEGALDQKNQILVKIYNRRASVVDEVVDELLAFADRVRPMVADTSLVLNEALDAGKNVVFEAGQATMLDVDHGTYPFVTSSSATAAGACTGSGIGPTRIDRVVGVIKAYTTRVGEGPFPTELHDEMGDLLRNSGGEFGVTTGRPRRTGWYDAVIARYASRVNGLTDFVLTKLDVLTGHQTIPVCVAYDVDGVRHDEMPVDQTAFHHAKPIYEELPGWSEDISGVRSFDDLPAAARDYVLALEEMSGCRMSSIGVGPDREATIVRHDLLG
>NZ_CP045920.1|WP_153878921.1|3360064_3360589_+|OsmC-family-peroxiredoxin
MTTTTIDLPDLAKQTTEQLAAGAPARVGFRTESRLTPGTNTAVDITAGRHEFTIDEPPALGGEDTGANPVEHLLAALSACQVITVRVWAAKLGLTVDTVAVDAHGTLDLRGFFGVDPAVRAGFQDIELDLTLTGPETEEAYAELIRVVEAQCPVLDNLTAGVPVTTRAHVAATA
>NZ_CP045920.1|WP_153878920.1|3358625_3359954_-|phosphoribosylamine--glycine-ligase
MRILVIGSGAREHALVHALTRDPSVTEIVAAPGNPGIAAQARAVPVDANSPDDVAALAEQVRPDLVIIGPEAPLVAGVADAVRAAGFPVFGPDGAAARLEGSKAFAKDVMAAAGVPTAMARVCTSEEEARDALDAFGAPHVVKDDGLAAGKGVVVTSDHDAALEHARGCLEGGVVIEEFLDGPEISLFCLSDGVTVVPLAPAQDFKRLLDGDAGPNTGGMGAYSPLPWAPDDLTEQVVERVALPTVQELARRGTPFVGLLYCGLALTSRGLRVIEFNARFGDPETQVVLARLLTPLAGPLLAAATGTLGDIEPLRWADGAAVTVVLASPGYPDAPRTGDVISGIERAESLPGVHVLHAGTASDGADGADGPDGADGADGADGADAGTAGGEADSVRSAGGRVLSVVGTGADLAAARAAAYAGVAEIAWPGMQYRTDIAAQVV
>NZ_CP045920.1|WP_153878919.1|3357466_3358399_+|GNAT-family-N-acetyltransferase
MSLTTSPLTIDHAGEWASLRRRINEVSGLLWKPTEQEMVEALAPSSTFDPARQTWGRWSGGSLVAFATVAVRDHPRHDGINAADIDSGVHPDLRGRGISSALLELAEPVAIELATARLPAVPLVLTAVASSTDQPSIDLLVDHDYSAVRYFFEMSHDLSGEASEDSRTREFTPADSEATRLAHNDAFRTHWGSGPASAEKWNQFMTSAGFRPDLSRIVERDGEVLAYGMVSSTVPGEAYLELVGTRAAAQGNGLGRAVLNSVVAAVRAAGGFTTLGLDVDADNPSGAGKFYGSAGFVNAARTITYEKPAR
>NZ_CP045920.1|WP_153878918.1|3356182_3357274_+|DUF4237-domain-containing-protein
MPAADPALIGALAAAVRSQADAQPAGEAGEAVSAEWSQAGSDHAGRLYTPAGRHPLGDDAVEAFGRLREAMTSPARGAWLSARIDVPADGPAEFTANFGQRPWWNAAGPSMLVPGDPGLAPHPPAEHWLAELMRHPRSREHWPTWLPWQDPLAEYARLREALDRAGVPRGAVRLPGEVHPYFEGAVVIRPIGHAVATAELTDYGQSVRLGDGTPAQMCRLVWDYVMSPLPPPLPLPAPDAAARMQAAAPALSALAARIRAAGPGGIATDLAPGLLFDRIGTLDGLYIYGWQAPLESRSLPSTATGAGATRVVFISRLAVPVQAELVPPWFGLPGGALRLRALDERTTVRDLVRGGALVPVRLA
>NZ_CP045920.1|WP_152910474.1|3355262_3356192_-|phosphoribosylaminoimidazolesuccinocarboxamide-synthase
MRACGRSYWLTGGRILYVTAPQLPGWRHVYSGKVRDLYEPTDGPADVVLVVASDRISAYDVILPTEIPGKGVVLTALSTWWFERMEPIIGNHLLSLDVPAAVAGRAMICRRLDMVPIECVARGYLTGSGLVEYRATSSVCGVALPEGLDDGARLPEPIFTPASKAAVGDHDENVSFEVVSARVGEELASRLREVTLAVYTRAAEISAERGILLADTKFEFGMDATGSLLLGDEVLTPDSSRYWPADQWQVGRAQPSFDKQYVRDWLTRDSGWDRASETPPPELPAGVVEATRARYLEAYERITGSPLPL
>NZ_CP045920.1|WP_153878917.1|3354836_3355172_-|hypothetical-protein
MAHAGGMSRWSLWSEDSFLSIGSRGSVLSVGSVGSAGSVCSIGSSLSLLSIASNLSVASLMSNLGVGAVMAGRGVGGVLGEARPGPHARRTACLAALTGAAVVLTLARRGR
>NZ_CP045920.1|WP_153878916.1|3354146_3354812_+|MBL-fold-metallo-hydrolase
MFPSLRPGDAPVTTTSGGLRITKIAVDYAMNNNAYLLECVRSGERALIDAAAEPDVLLEAIGLGALATVVTTHAHWDHHRALAAVVRATDAAVVAGAADAAEITAQTSVIVDRAVTGGDVVMVGDVPLAVVSLVGHTPGSIALIHRPDGATPHAFTGDSLFPGGVGNTHGDPAAFASLLAGVRATLFDELPDEAVVHPGHGDDTTLGAERGSLDEWERRGW
>NZ_CP045920.1|WP_152910477.1|3353772_3354027_-|phosphoribosylformylglycinamidine-synthase-subunit-PurS
MPRLIVEVMPKPEILDPQGKAVAGSLPRLGFADFASVRQGKRFELEVAGEVTEELLATARRAAEEVLSNPVIEDVVAVYEQVEQ
>NZ_CP045920.1|WP_153878923.1|3366041_3366452_-|DUF3151-family-protein
MRNLLGDPDPTLLPAEEDSAARADLTAGRSAREVAAAHPAVSYPWSLLARAALAEDDVIAGYAFARTGYHRGLDALRRSGWKGHGPVPASHVPNRGFLSCLLSLEAAAAAIGEHDEAERCRIFARDCDPEAASLLA
>NZ_CP045920.1|WP_153878924.1|3366869_3367166_+|DUF503-family-protein
MWIGAIEFDLLLGDVHSLKEKRSVVRPLIAEVRRRFEVSVAEVGHLDLHRRALVGAAACAADAGHVVEVIDHLERLVAARPETELLSARRRLFNTDDE
>NZ_CP045920.1|WP_153878925.1|3367314_3368265_-|hypothetical-protein
MVGAQGKVVVGFDASDESRVALQWAIAVANRRQVPLLVVHATGLEDPGPTVYRAGVAVMSQRRAQEIAEDGAAIARREATVEVEAAGVERGAVAALVDYSDGAELIVVGNRGRGRLRGALLGSVAFDVTTHARCPVAVVRGSLRPLPSADIPIVVGIDGSENGETALDEAARLAAATQSYLRIAVAWSTPGRNLWRSSFTHHEDDAREGEGASDNPWTNKAHAENEQADRPATDVPESASALAERAAEHVSSAHPGLRVELVVAEGRAEEVIVDAADGASLIVVGARGRGDFASLMLGSVSRDVIQHAECAVYVVR
>NZ_CP045920.1|WP_153878926.1|3368759_3370460_+|DUF222-domain-containing-protein
MRMSEPQPTQPARGGSTPGEGIGAGADDAAGEIGAARVAGPGNTARADAAGSTAGAAVTAAGAAGTTADAAGAAGTTVAAAGAVLEGLEVLAQTSWADLPAPMVIELVDQLEQAQRRLEGARAGALSAVEADGSWALQGARTFTSWLRNHSGAAAGATSRRVRESRALRDHLPATATALAHGRIGTDHLRILARDATRTQRLRDQLTDPDLGETFLLTHAQTLDADRFAKLVAAWAIRTDPEAADRAWREDTGKEELSLAPTTGGYHLTGWLTTTSGQALDTALTAHMGRKSQDDQRTPNQRRAAALTGLARESLDTGTHGTSARIRPHLTVTVPWNTLRALTTTHHPDQPAEHHADPAEPHAESAEPHGDPAEPHGDAAHSADPADDGDHGDHGDHGDHGEYSLATGLDYEALRGLEPATFPDGTPLAPGLLARLACGSQLSRVVFGPDSTILDVGREKRIFPANQVRGIIARDRHCQYPACDEPPGYGEIHHSRWWWQHNGTTSTAQGILLCWHHHDLVHQREITITRRSGTWTFTDRHGHPLTATPHSHRGTTTNPPGEPRTT
>NZ_CP045920.1|WP_153879307.1|3370069_3370888_+|transposase
MRLPTLPRRLRTRLHDPGRRPRETHLPRQPGPRNHRPRPSLPIPGVRRTTRLRRDPPLPMVVATQRHHLDRPGHPAVLAPPRPRPPTRDHHHPPQRHLDLHRPPRPPPHRDPPQPPRHHHQPARRTQNHLSNQGFSRTDTTRDINAGPSPVWWTVGLAAVDKGGSTVGSTRRSFTDEYKASAVAFVLDEQRSIAEVARNIDVHEMTLGKWVKKERDTREAALGADASLSESERAELIRLRQDYKNVKAENAQLQMQVSFAKKVATWFASEQQ
>NZ_CP045920.1|WP_153878927.1|3370773_3371769_+|IS3-family-transposase
MDPAAAGLQEREGGECSVADAGEFRKKSGDLVRERTAVKFAAIADWADQQEYPVAFMCRQLGVSRAGYYKWRDAPLSDRAVYDERLSVLIAGIYASARGNPGVRRVRAGLAAAGHRVGLKRVHRLMQAAGLQGRHPRAWKRTTVPGQGPVPAPDLIGRSFTAEEADTRWCGDITYVKTWEGWAYLATVIDLHSRALVGWAIEDHMRTDLVTDALDMALKTRKPPAGVIFHSDRGTQYTSTAFAKYCEDHNIRRSLGRTGVCYDNAVSESFFATYKKELIHTRPWPNLTRLRKATIDWITNYYNTIRRHSTLGYLTPTEYELGYRNINELAA
>NZ_CP045920.1|WP_153876953.1|3371901_3373227_+|ISL3-family-transposase
MDEFTGSQRDAASTIFNLSDYRVIDAIDLPGGGRRVVIESLAPPGCPACGVIAVKIHSRRRQRLRDLPIAGAVEVWWAKRRWFCREELCGRGTFAESTIQVPRFARSTTRLKNQVVAAVVDSGRAASEVARAHGVSWWLVQSALAAAALVLPAADDWVVTRLGIDEHRYRSVRFFRDEHGAWRRFEPWMTTLVDLATGQVLGIVDGRDSTGVGAWLSARPQSWRDRIEVVAIDPSAAFRKALREHLPHAAVSVDKFHLVKLAGDMLTKVRQRLARDQHGRRGRKSDASWAHRMLLLRGADTLSPRGWARLEKVFTDDDPTDELSAAWGVKEQLRRLLGADTLAQAWQERMRLGHYVQTANMAETDRLYETIVTWWEAIEVLIVTGATTAKVEAANTTIKNIKRTGRGFRNSANYKARILLASAARAAARTPITAGLSPRTA
>NZ_CP045920.1|WP_153878928.1|3373437_3374163_+|helix-turn-helix-domain-containing-protein
MTKPTLIHSVVRALSLLDAVGTSVVPLTAKQLARRTTVPLSTTYHLLRTLVHEGYLACFQGGYVLGSEVYALRSPTGIDARRAREALTDLHNDSGAAAYLAALRGEEIWIVDIIDDPTTPRVDLWVGLHEAAHATALGKAILRAMAPAQRSEYLGRHRLADLTPHTITNPRRLLNEVTHAEFAVDNQEYAVGTSCLALPVPSTSWTAAVAISLPATRAGDLGRHAVRMRRAATRIALDTAA
>NZ_CP045920.1|WP_153878929.1|3374382_3375417_+|pyruvate-dehydrogenase-(acetyl-transferring)-E1-component-subunit-alpha
MSSQVASPPPPPSDPPPDDVRRDLFTTMVLSRTYEEAILREYHADKGPGFDIGKGLVPGEMHLSAGQEPVAAGVCAHLRPDDALTATHRPHHLAIAKGVDLDRMTAEIFGREDGLGRGRGGHMHLFDPAVHFSCSGIVAEGLPPALGQAFAFQRRGTDAVAVAVMGEGAANSGAFHESLNLAALWTLPVIFVIEDNDWGISVPRSASTSVPSNAVRAAGYGIPGETIEGNDVDAVHAAAGRAVARARAGEGPSLLEIRTLRLWGHFEGDAQGYRPDLDTVPEHDPLPRYEQRLRDAGILDDISVKQAYADATDVVEAAIDYAKSSPIPDPADVHKYVFAEEATR
>NZ_CP045920.1|WP_153878930.1|3375413_3376445_+|alpha-ketoacid-dehydrogenase-subunit-beta
MTAADTSSAPTRRLNTSKAMVEAIAAEMEVNSEVFYMGEDVGAYGGIFGSTTGLLERFGPSRIIDTPISETAFIGLGIGAAVEGMRPIVELMFADFVGVCLDQIYNHMAKIHYFSGGNVTVPMVLTAAVGGGYADGGQHSQTLWGTFAHLPGMKVVAPSNPADAKGLMTAAIRDDSPVVYMFHKGVMGLPWMAKNPRSIGPVPDGEHIVPIGRAAIPREGTDITVVTLSLSVHHALDVAEKLAGEGTSVEVIDLRSIVPLDREAILASVAKTGRLVVVDEDYLSFGLSGEVAATITDVDPGLLKAPVRRVALPDLPIPYAHGLEYAALPRPERIEAAIREVLD

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP045920_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045920_12

3427773-3427857

Orphan

Consensus_repeat	Method
GGGACGACAGTCAGTCTCCCCGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045920_12

>merge|NZ_CP045920|12|3427773-3427857|CRISPRCasFinder
GGGACGACAGTCAGTCTCCCCGGGTGCGGCCACGCACCACGGCCGGGGAAGCTGGCTGTTCCGGGACGACAGCCAGTCTCCCCGG

>NZ_CP045920|12|10|3427773-3427857|CRISPRCasFinder
GGGACGACAGTCAGTCTCCCCGG	GTGCGGCCACGCACCACGGCCGGGGAAGCTGGCTGTTCC
GGGACGACAGCCAGTCTCCCCGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045920.1\|WP_152909763.1\|3436019_3436385_-\|Na+/H+-antiporter-subunit-G	unknown	unknown	gnl\|CDD\|237169
NZ_CP045920.1\|WP_153878954.1\|3424299_3426177_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP045920.1\|WP_153878956.1\|3427923_3429108_-\|pirin-family-protein	unknown	unknown	gnl\|CDD\|224655
NZ_CP045920.1\|WP_153878962.1\|3436381_3436774_-\|pH-regulation-protein-F	unknown	unknown	gnl\|CDD\|181179
NZ_CP045920.1\|WP_153878951.1\|3419631_3420237_-\|nucleotide-exchange-factor-GrpE	unknown	unknown	gnl\|CDD\|271355
NZ_CP045920.1\|WP_153879311.1\|3430155_3431232_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|226361
NZ_CP045920.1\|WP_153878960.1\|3434937_3435219_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045920.1\|WP_152909760.1\|3434597_3434846_+\|DUF4235-domain-containing-protein	unknown	unknown	gnl\|CDD\|379422
NZ_CP045920.1\|WP_153878949.1\|3414139_3417259_-\|family-20-glycosylhydrolase	unknown	unknown	gnl\|CDD\|119336
NZ_CP045920.1\|WP_152909747.1\|3417573_3418146_-\|DinB-family-protein	unknown	unknown	gnl\|CDD\|378981
NZ_CP045920.1\|WP_153878961.1\|3435794_3435998_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045920.1\|WP_152909750.1\|3420233_3422111_-\|molecular-chaperone-DnaK	unknown	unknown	gnl\|CDD\|234715
NZ_CP045920.1\|WP_153878948.1\|3411942_3414033_+\|prolyl-oligopeptidase-family-serine-peptidase	unknown	unknown	gnl\|CDD\|224422
NZ_CP045920.1\|WP_153878955.1\|3426334_3427306_+\|glutathione-S-transferase-family-protein	unknown	unknown	gnl\|CDD\|223512
NZ_CP045920.1\|WP_153878959.1\|3433068_3434376_-\|thiamine-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270263
NZ_CP045920.1\|WP_153878953.1\|3423139_3424063_+\|DUF559-domain-containing-protein	unknown	unknown	gnl\|CDD\|380141
NZ_CP045920.1\|WP_153878950.1\|3418209_3418716_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133394
NZ_CP045920.1\|WP_153878958.1\|3431314_3433069_-\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|224099
NZ_CP045920.1\|WP_153878957.1\|3429112_3430006_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|225312
NZ_CP045920.1\|WP_153878952.1\|3422287_3422875_+\|DUF2809-domain-containing-protein	unknown	unknown	gnl\|CDD\|378530

Protein	Function_ID	Function_description	E-value
NZ_CP045920.1\|WP_152909763.1\|3436019_3436385_-\|Na+/H+-antiporter-subunit-G	gnl\|CDD\|237169	PRK12674, PRK12674, putative monovalent cation/H+ antiporter subunit G; Reviewed.	1.48991e-27
NZ_CP045920.1\|WP_153878954.1\|3424299_3426177_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	8.26506e-142
NZ_CP045920.1\|WP_153878956.1\|3427923_3429108_-\|pirin-family-protein	gnl\|CDD\|224655	COG1741, COG1741, Pirin-related protein [General function prediction only].	6.44943e-45
NZ_CP045920.1\|WP_153878962.1\|3436381_3436774_-\|pH-regulation-protein-F	gnl\|CDD\|181179	PRK07948, PRK07948, putative monovalent cation/H+ antiporter subunit F; Reviewed.	7.77908e-18
NZ_CP045920.1\|WP_153878951.1\|3419631_3420237_-\|nucleotide-exchange-factor-GrpE	gnl\|CDD\|271355	cd00446, GrpE, nucleotide exchange factor GrpE. GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. In bacteria, the DnaK-DnaJ-GrpE (KJE) chaperone system functions at the fulcrum of protein homeostasis. GrpE participates actively in response to heat shock by preventing aggregation of stress-denatured proteins; unfolded proteins initially bind to DnaJ, the J-domain ATPase-activating protein (Hsp40 family), whereupon DnaK hydrolyzes its bound ATP, resulting in a stable complex. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding. In eukaryotes, only the mitochondrial Hsp70, not the cytosolic form, is GrpE dependent. Over-expression of Hsp70 molecular chaperones is important in suppressing toxicity of aberrantly folded proteins that occur in Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis, as well as several polyQ-diseases such as Huntington's disease and ataxias.	6.88285e-32
NZ_CP045920.1\|WP_153879311.1\|3430155_3431232_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|226361	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism].	5.5114e-105
NZ_CP045920.1\|WP_152909760.1\|3434597_3434846_+\|DUF4235-domain-containing-protein	gnl\|CDD\|379422	pfam14019, DUF4235, Protein of unknown function (DUF4235). This family of integral membrane proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 88 and 119 amino acids in length.	4.65567e-15
NZ_CP045920.1\|WP_153878949.1\|3414139_3417259_-\|family-20-glycosylhydrolase	gnl\|CDD\|119336	cd06568, GH20_SpHex_like, A subgroup of the Glycosyl hydrolase family 20 (GH20) catalytic domain found in proteins similar to the N-acetylhexosaminidase from Streptomyces plicatus (SpHex). SpHex catalyzes the hydrolysis of N-acetyl-beta-hexosaminides. An Asp residue within the active site plays a critical role in substrate-assisted catalysis by orienting the 2-acetamido group and stabilizing the transition state. The GH20 hexosaminidases are thought to act via a catalytic mechanism in which the catalytic nucleophile is not provided by solvent or the enzyme, but by the substrate itself. Proteins belonging to this subgroup lack the C-terminal PKD (polycystic kidney disease I)-like domain found in the chitobiases.	2.29542e-99
NZ_CP045920.1\|WP_152909747.1\|3417573_3418146_-\|DinB-family-protein	gnl\|CDD\|378981	pfam12867, DinB_2, DinB superfamily. The DinB family are an uncharacterized family of potential enzymes. The structure of these proteins is composed of a four helix bundle.	2.57331e-05
NZ_CP045920.1\|WP_152909750.1\|3420233_3422111_-\|molecular-chaperone-DnaK	gnl\|CDD\|234715	PRK00290, dnaK, molecular chaperone DnaK; Provisional.	0
NZ_CP045920.1\|WP_153878948.1\|3411942_3414033_+\|prolyl-oligopeptidase-family-serine-peptidase	gnl\|CDD\|224422	COG1505, COG1505, Serine proteases of the peptidase family S9A [Amino acid transport and metabolism].	0
NZ_CP045920.1\|WP_153878955.1\|3426334_3427306_+\|glutathione-S-transferase-family-protein	gnl\|CDD\|223512	COG0435, ECM4, Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones].	9.5955e-125
NZ_CP045920.1\|WP_153878959.1\|3433068_3434376_-\|thiamine-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270263	cd13545, PBP2_TbpA, Substrate binding domain of thiamin transporter, a member of the type 2 periplasmic binding fold superfamily. Thiamin-binding protein TbpA is the periplasmic component of ABC-type transporter in E. coli, while the transmembrane permease and ATPase are ThiP and ThiQ, respectively. Thiamin (vitamin B1) is an essential confactor in all living systems that most prokaryotes, plants, and fungi can synthesized thiamin. However, in vertebrates, thiamine cannot be synthesized and must therefore be obtained through dietary absorption. In addition to thiamin biosynthesis, most organisms can import thiamin using specific transporters. After binding thiamine with high affinity, TbpA interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The thiamine-binding proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	2.05551e-101
NZ_CP045920.1\|WP_153878953.1\|3423139_3424063_+\|DUF559-domain-containing-protein	gnl\|CDD\|380141	pfam18741, MTES_1575, REase_MTES_1575. Vsr REase Fold. Fused to HEPN (SWT1/Abi2 family), along with Transglutaminase and wHTH.	1.11911e-10
NZ_CP045920.1\|WP_153878950.1\|3418209_3418716_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133394	cd04766, HTH_HspR, Helix-Turn-Helix DNA binding domain of the HspR transcription regulator. Helix-turn-helix (HTH) transcription regulator HspR, N-terminal domain. Heat shock protein regulators (HspR) have been shown to regulate expression of specific regulons in response to high temperature or high osmolarity in Streptomyces and Helicobacter, respectively. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their conserved N-terminal domains contain predicted winged HTH motifs that mediate DNA binding, while the dissimilar C-terminal domains bind specific coactivator molecules.	9.36474e-37
NZ_CP045920.1\|WP_153878958.1\|3431314_3433069_-\|ABC-transporter-permease-subunit	gnl\|CDD\|224099	COG1178, ThiP, ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism].	3.20521e-84
NZ_CP045920.1\|WP_153878957.1\|3429112_3430006_-\|VOC-family-protein	gnl\|CDD\|225312	COG2514, COG2514, Predicted ring-cleavage extradiol dioxygenase [General function prediction only].	1.03791e-71
NZ_CP045920.1\|WP_153878952.1\|3422287_3422875_+\|DUF2809-domain-containing-protein	gnl\|CDD\|378530	pfam10990, DUF2809, Protein of unknown function (DUF2809). Some members in this family of proteins are annotated as yjgA however currently no function for the protein is known.	2.2103e-07

>NZ_CP045920.1|WP_153878955.1|3426334_3427306_+|glutathione-S-transferase-family-protein
MGEQATYVESGKEFTRDMNYIPDRITATPGVSADPLDETADRGSARIDVPTWPVEPGRYRLVAAKACPWANRSLIVRNLLGLQDVVSVGMPGPTHDARSWTFDLDEGGLDPVLGIERLQQAYFARYPDYPRGITVPAIVDVPTGRVVTNDFPWITHDFFFEWREHHRAGAPDLWPVEQREEMERVMRRVFTEVNNGVYRCGFAGSQEAYNDAYDRLWTALDWLEDRLRGRTYLMGENLTEADIRLFTTLVRFDAVYHGHFKANRNKLTEMPNLWRYAKHLYNIPEFGSTVDFDQIKEHYYVVHRDVNPSGIVPKGPDLSVWTA
>NZ_CP045920.1|WP_153878954.1|3424299_3426177_-|ATP-binding-cassette-domain-containing-protein
MSALARILRFTRSLTPYYIGIMIVAAITTGAALAVPFLTGHATDVIVATIDGDGEVGAAVRTVVLIAAAVLAAELLNSVVSNIGGYWGDVMSARMRTILSVRYYDKLLQLPQRYFDNELTGTIVARLNRSINEIANFAKTVSNMFATLTLTTIAVLAVSAWHYWPLAVLLFIAYPVYLWLTALTSRRWQRLEGRKNTHVDLASGRFNEVVGQIRVVKSFTRERSELAGFTDHFDATVDLTREQSVYWHRMDALRRGVLNLIFFALYALIFVRTVRGHLSVGQMVMLVQLMAMAREPVTSLSWVVDSAQRAIAGSKSYFEVMELDPAVLAAALPASVGTTQPASGAPLAEPVLVEEGEARTSGGSGGSGASMISFDDVRFGYDTDPNVIDGISFEVAPGEKIALVGESGGGKTTIVNLLLGLYRMRSGRIEVAGLDVATADLDEVRRSIGVVFQDASLFSGTIRENIVYGAPGAGDEEVAEVAGRAAVDEFVRKFPDGFDTVIGERGMKLSGGQKQRIAVARAMLKDAPVLVLDEATSALDTKSERLVQAGLDDLMAERTSLIIAHRLSTIAGVDRIITLRDGRIDELGPPAELAASGGIYAELLSLQNSTAKADRRRLRTYDVVG
>NZ_CP045920.1|WP_153878953.1|3423139_3424063_+|DUF559-domain-containing-protein
MTSTGPPTARRLVAALAARQHGIVARRQVLERGMSKAQIQSRLDTGEWVSIHGGVYGISAAPRTPGSRATAALLYAPAGSALSHLTAARLLDLGVRSGSGAIWISIPHGHRRIPSSGLRFVRSRTLDSFITTMHGWRVTTPARTIVDLATILPPGRLIPVAYDAVRTRVASIEEIARAARAVSARADAPRLRRLLDELDSTFDSGLEVEADHAFRANGLIFEHQYEVFNGDQFVARVDFADPRLKIAIEIDGARYHSSAEAQERDRRRDRRLSELGWHPAHFGTDDVRRRPAEMVAHLRELIAQRAT
>NZ_CP045920.1|WP_153878952.1|3422287_3422875_+|DUF2809-domain-containing-protein
MTTITVEDAWLLPAGGTLRRLSGALGSSATCGRRARIPCTSGTAGAPCGADRGRAWLTAAMAFGRRRSRSRTLLALALVVAAGLALQTARTLPGSDVAGTVLYATALVLLIAALLPRLGATGSAALGTAVALAVEFAQLTPLPGVVVERIPSARLVLGSAFDPIDVLGLIAGGIAAWLLVRALDHPSRRAATPSP
>NZ_CP045920.1|WP_152909750.1|3420233_3422111_-|molecular-chaperone-DnaK
MARAVGIDLGTTNSVVAVLEGGEPTVIANAEGARTTPSVVAFSKAGEVLTGEVAKRQAVTNVDRTISSVKRHMGTDWSVDIDDKTYTAQEISARVLGKLKKDAESYLGEPVTDAVITVPAYFNDAERQATKDAGQIAGLNVLRIVNEPTAAALAYGLEKGKEDELILVFDLGGGTFDVSLLEVGKDEDDFSTIQVRATNGDNRLGGDDWDQRVVDWLVTQVKNGTGVDLSKDKIALQRLREAAETAKKELSSATSTTISLQYLSMGENGPIHLDERLTRAQFQDMTKDLLERTKTPFHNVIKDAGIALSDIDHVVLVGGSTRMPAVTEVVKELTGGQDPNKGVNPDEVVAVGAALQAGVIKGERKDVLLIDVTPLSLGIETKGGVMTKLIERNTAIPTKRSEVFSTAEDNQPSVLIQVFQGEREFARDNKPLGTFELTGIAPARRGMPQIEVAFDIDANGIVHVSAKDRGTGQEQSMTITGGSALPKEEIDRMVAEAEAHAAEDAKRREEADVRNTAEQQVYSTEQLLTDNADKLPEDVAASVRESVTKLQEALKGEDLEAVKTAQSELTTESQKIGEALYAAGQAEGADGAAGAEGATGEAPAGGSNDDDVVDAEIVDEDEEKK
>NZ_CP045920.1|WP_153878951.1|3419631_3420237_-|nucleotide-exchange-factor-GrpE
MTPADQEEPVIRDKRKLDPVTGELREGGAAAAGGATAPGAAGAEDAAPESEELATVRAEALDLADDLARAKADLYNLDQRFNTYVQRSKADAADAFGRGQADAVEALIPVLDDIELARRHDELHGPFASIAEKLETTLSQRYRVERFGQVGEEFDPTVHEALMHRASEDVATDVIDVVMQPGYRVGDRVVRPARVGVAGPE
>NZ_CP045920.1|WP_153878950.1|3418209_3418716_-|MerR-family-transcriptional-regulator
MRRARSRTSRPPATAPTRGSAWPKRRRPEGRPMARYDAPIYLISIAADLAGMHPQTLRSYDRLGLVVPQRTAGRGRRYSPRDVDVLREVQRLSQEEGINLAGIKRILELAVRNEELELENARLRERQATSQRVFAASSSGDVVALPLGTRLRRAEGVSRALVVWRQGR
>NZ_CP045920.1|WP_152909747.1|3417573_3418146_-|DinB-family-protein
MSADTPQHAQGPEVPVDTQDWTWVLSRTCPDCGLTSADFEPVQVADAATRIAAAFEGLLTSGSADLHRRPAPGVWSPIEYAAHVAEVCQVFDRRLGLILIRVDPEFPDWDQNRAAVDGGYGSRAPRAVAEELQHSAHALAVAIHAVPASEYERTGLRSDGTRFTVVTLLQYALHDLVHHWWDVSGQRAIR
>NZ_CP045920.1|WP_153878949.1|3414139_3417259_-|family-20-glycosylhydrolase
MTNQTLRAEIAHGRASTVVLAATASLALAGAMVIPAAADTGDPENLSLASTVTASGQEVGDRWGPRLTIDGDHGPAENRSDPTVHNAPDSSRWSANNSDDAWIDIHFAQESAVSEVAVDWGNTFGDPYALSISEDGVRWEEIATGITGVRDGIVVTELDEPATGSHLRLQISGKSQQWALAIWEIEVLGTPIGQPPVDAVPLDASLVPLPLEATATGGAGFTLAADSCLSLSDASLEAVADRLREAIGTSTGLTLPTGQDCAVSLAIDESLSVGAGRDEEAYTLDVDENGVRIVAHSPRAALWAVRTLVQLLGPWAQAPVALDVAPTLEAVHIEDAPRYAWRGFMLDPARSFWPVEEVEELIDLISQFKLNVLHVHLSDDQGWRIAVDNEGRADADTIDYTELTERSGATAYMAGKSNYAPAAGRTGFYTRAEFSGLVAYAAERGVMVVPEIDGPGHANSMLHAIDELNTAGAFPKPAAGNTRVDAFDESTFAQTTLDPRSEATYTFLTHVLSQLVDDTIAGVAAAEGAGAALAPASPYLHIGGDESATTTGDDYAHYMERVTEIVTETGRLPIVWNEATSTPDALPDGTVVQQWNGGISQGTRDLVENRGGKILLSQVGNAYYPQIPTTDLSGPSWACGGTACGIDDFYNWNPTSMAGVDEAGVLGVEGPMWSEHLRTLHDLQFLVFPRLLAHAEVGWTPQARRSFADFTGRVPAAGVSLLTQDATFQLVPEVTDWYSSFAPAPVADVSQAGGEVLVGYVAAPGTAEVADATVTATLADVDVPVRLAMERGFHYTDEGRTTGRVMNSLIEVYAQLPEFAEAGTYELAVRGTVPVGEVAGAVTIEVAAEDGGDADAGSDGSDGDTDTGADGDAGTGGSEAGGSSDAGAGADSSGSGSGGDADAGGTDTDTGSDGDAGTGGSEAGGSSDAGSSDAGAGADSGGVDSGGTDAAGTETGADPESGGTEAGAAATSADAGSDAAEGADDGADDGADEGVDDGADPAPGAMPDTGVQPTGIALAALLLIAGAVFTLRRRAAHRS
>NZ_CP045920.1|WP_153878948.1|3411942_3414033_+|prolyl-oligopeptidase-family-serine-peptidase
MKARMRRLIHPSSRTSVTCVSDPFAWLEDVDSDEALAWVRERNGERAAELAAGAGFAALQERILGILDSRDKIPSVSKIGEHYYNFWRDEDHERGLWRRTSPESYASEDPDWEVVLDLDELGRVEGENWVWHGASVLRGAGEYRLALVSLSRGGSDADVTREFDLVAKDWVEGGFHRPESKGGMGWIDADTAFVYTDTGPGSMTSSGYPRLARRWTRGTDLAAAPIVYEGTPEDMYVAALHDSTPGFERDLVVRTIDFYSSEAFLLADGRLTKIDVPDSAEIDLHREWLTVELREEWAPGGEAGAPVHAAGSLLAIPHEDFLAGARDFRVIFAPTPATSLVGAAWTRSHLVVNVLEDVKTRLHVWTPTGGAFVRGEFPGVPDVGTVGVRPVDEKFSDDVWVVTTDFLTPTTLQLATVGGAPSPLKSQPRFFDASDLVTTQRFTRSADGTRVPYFLIHRREVPLDGSTPTLLYGYGGFEISLTPSYSGVLGAAWLERGGAYALANIRGGGEYGPTWHQGALRENRHRAYEDFAAVARDLVASGLTSREHLGIQGGSNGGLLTGNMLTGYPELFGAVVIQVPLLDMKRYSHLLAGASWIAEYGDPDTDDWEFMESFSPYHQIDPERAYPPVLLTTSTRDDRVHPAHARKFAAALAAAGQDVTYFENVEGGHGGAATNAQAAHMAALAYEFLATRLGPA
>NZ_CP045920.1|WP_153878956.1|3427923_3429108_-|pirin-family-protein
MTNLEAHPGETVAEPDVRCPRQLQVFAPRTVPLGGIRAIPVRRTLPHRRLPTIGAWCFLDQFDGGDGAAAMTVLPHPHTGLQTVTWPVAGRIRHRDSLGSDVHVNPGELNLMTAGRGVSHSEFSEAGSPLAGVQLWLASPSGPDSGPPDFEQVTELPAVSGAGYRFEVFIGELAGARSPARVFSPLVGADGVIEPGASVRLAVERGWEHGLLVFAGGIEPAEPVDEYVPDRSPSGRVAGGGGAQSSAGTRGGDGVGGGAVGAGVDEGAGADALRGRIGAGNLVYFGGDRDHLEFTAGDEGARVILIGGEPFEEPVVMFWNFVGRSHDDVARASADWAADWDGGAAGPDAAPGSTGAPAGDPARRPRRFGTVPGHGGDHIPGPELPAVTLRPRRR
>NZ_CP045920.1|WP_153878957.1|3429112_3430006_-|VOC-family-protein
MTRTLAPDTSMGVVDLLVRDPDAMVAFYTAGVGLAVLGQAGPTVTLGRSRNPVVRLTRESDLPDFDRGDAGLFHTAVLYPTQADLAAAVLSTVRHAPAAFTGSADHLVSEAFYFDDPEGNGVELYTDRARSSWTYAADGSVRMATNLLDPNTYLQDHLDDAGMTGAQHAAASVGHVHLQVGDIDLARDFYAGVLGFEVTSRFGSQALFVAAGGYHHHIGLNSWNSRGAGPRAASLGLGQVAIEVPAGEEIERIAHRLGRNGVDHRTVDGSLQVRDPWATLIEIRPRGLEPARAGVAV
>NZ_CP045920.1|WP_153879311.1|3430155_3431232_-|ATP-binding-cassette-domain-containing-protein
MPSARSDAGPAASPDPAATADPPIALGLAQVEVRYPGAASPAVDTVDLHVRAGEVLALLGPSGCGKSSLLRAIAGLELPSAGTIAWAGRDLAGVPAYRRGFGLMFQEGQLFPHRSVAGNVEFGLLMDRVPRAARRERVRELLDLVGLAGYGDRPTATLSGGEQQRVALARALAPRPRLLLLDEPLSALDRSLRERLTVELATILRRAAATALYVTHDHDEAFTIADRVGIMRAGRLVQVGRPAEIWSRPADAPVAAFLGFAVISDDDDRTWALGPRALWVTAPGESSAPAAGPIAPRTGRIRSLGFQRGEPAARLDVPGWGTVRALLRPASAGGPDRPAPGDVVQVDVDPLGVVLLEG
>NZ_CP045920.1|WP_153878958.1|3431314_3433069_-|ABC-transporter-permease-subunit
MTAAPTRTGPPAGPGQGSGQEPDRRPGRPRGFARGRLGVPAWTVAVAVPTVFLAIFFVYPAGTLIATGFVSDGHLDLGGVADVLGRSRTWRLLGLTLGQALVGTALSVALGLPGAYVLYRRRFRGQGVARALVTVPFVLPTVVVGVAFRALLAEGGPLGFLGLDGTVTAVIAALVFFNYAVVVRSVGALWQRLDPRAEQAAAALGASPWRVFRTVTLPSLVPAIASAASLVFLFCATAFGIVLVLGGPRVGTIETEIWIQTTQFLDLRAAAVLSVLQVVIVIGALIGSNVARRRREVALRLTGLTVAPRPLRWRGGDGAAIAVTAVTVAILHVLPMAHLLLASLRTPDGWGLGNYLALGGTGEHSALSVSVWQAAANSLRVAVDATLLAVTIGTLVAVVVSRSPRRPWLRRGAAGLDAAFMLPLGVSAVTVGFGFLITLNRPPLDLRESLILIPIAQAVVAIPLVVRTVAPVLRAIDPRLREAAAVLGAAPGRVLRYVDGPFLLRALGPAIGFAFAVSLGEFGATSFLSRPERPTLPVVIFRLIGRPGEQNYGMALAAAVILAILTATIMTLAERLRGEHSSDF
>NZ_CP045920.1|WP_153878959.1|3433068_3434376_-|thiamine-ABC-transporter-substrate-binding-protein
MTQDFRSQPDSTSSAAPAAAAPAAASAPQVVASDPRRGRRHPDRHLNRHENGHEVRHAGHHPGRHPDPHSGRHPGGHQGRLGTRVALPALAALTGAALAGCSLAGGGAPEPAGSVSQPTTVRVVTHDSFNLDEALLDSFEAETGYTLEFSAPGDGGTLVNQLILTKDSPLGDVAFGIDNSFAGRALAEDVFADYTPADLPASAAAYAVDGDSAALTPIDVGDVCMNVDHQWFADHDLDEPVTLDDLTLPAYADLTVVSNPARSSPGLAFLLATIGEYGDQWVAYWQRLDENGLKIVDSWSDVYYTDFTAAEGAGGTRPIALSYSTSPAFTITDDGDSTTGALLETCFRQVEYAGVLAGAENPAGAQAFLDFLLSAPVQADIPGQMFMYPVDDTVRLPADWVAHAPLAPNPITVPQADIDAHLDEWLRTWQEQVVG
>NZ_CP045920.1|WP_152909760.1|3434597_3434846_+|DUF4235-domain-containing-protein
MNSQKLINMAIVMGAGFAATKAISLAWKGVTGHEPPKEIDDDGEISITEVVIFAAVSSAAAALVKAYASKGAKHLTARPADR
>NZ_CP045920.1|WP_153878960.1|3434937_3435219_-|hypothetical-protein
MTATEQMAVVAREPVAGGGAAGDRLDLDQGEIAGIDVGQGETSGVRVDQGETAGSWCDSTGFTLLGGAAVAAAAARDALGRRRSRWQSGDRFE
>NZ_CP045920.1|WP_153878961.1|3435794_3435998_+|hypothetical-protein
MGSTAEQGEVGGIGPRSNDLPLVDADTGGFALVDTQTGGLALVDEDSSGFALVGTQTGGFALVDAPG
>NZ_CP045920.1|WP_152909763.1|3436019_3436385_-|Na+/H+-antiporter-subunit-G
MIDQIIEVLAAICFITGSLLTLVAAIGLVRFPDLLSRMHAATKPQVLGITLLMSGLALSFQEVQVAWKVVLVVALQMISSPVSAHLVGRSGYRTKKIPSDLLIVDELRDDLDAAREPDSSS
>NZ_CP045920.1|WP_153878962.1|3436381_3436774_-|pH-regulation-protein-F
MNEIVMIVCGVLLTAAALTVLFRLERGPSMLDRIVALDVLVAVVIATLTIWSAWTGRRDLTVILVVLASVGFIGSVTLARFAAVDPPSVEDAEAARIEAVRERLARVRARMESEQRDARRRMGPEGRPRE

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP045920_13

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045920_13

3476791-3476877

Orphan

Consensus_repeat	Method
AGACGACCGGGGCGATCCGACCACC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045920_13

>merge|NZ_CP045920|13|3476791-3476877|CRISPRCasFinder
AGACGACCGGGGCGATCCGACCACCCCACAGGTAGTCACGGCCACCCACATGGGTGCGCGTCAGACGACCGGGGCCATCCGACCACC

>NZ_CP045920|13|11|3476791-3476877|CRISPRCasFinder
AGACGACCGGGGCGATCCGACCACC	CCACAGGTAGTCACGGCCACCCACATGGGTGCGCGTC
AGACGACCGGGGCCATCCGACCACC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045920.1\|WP_153878983.1\|3465970_3466735_-\|Asp/Glu-racemase	unknown	unknown	gnl\|CDD\|226004
NZ_CP045920.1\|WP_153878993.1\|3477222_3477975_-\|branched-chain-amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224215
NZ_CP045920.1\|WP_153878997.1\|3485308_3485764_+\|phosphoribosyl-ATP-diphosphatase	unknown	unknown	gnl\|CDD\|212137
NZ_CP045920.1\|WP_153878984.1\|3466857_3467934_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|240652
NZ_CP045920.1\|WP_153878987.1\|3470901_3471825_-\|transporter-substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|270225
NZ_CP045920.1\|WP_153878988.1\|3472362_3473313_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045920.1\|WP_152909775.1\|3480111_3481326_-\|cation:proton-antiporter	unknown	unknown	gnl\|CDD\|223551
NZ_CP045920.1\|WP_153878995.1\|3479443_3480067_+\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|366102
NZ_CP045920.1\|WP_153878994.1\|3478110_3479352_-\|NAD(P)-binding-protein	unknown	unknown	gnl\|CDD\|223727
NZ_CP045920.1\|WP_153878996.1\|3481972_3485272_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223627
NZ_CP045920.1\|WP_153878985.1\|3468027_3468927_-\|transporter-substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|270225
NZ_CP045920.1\|WP_153878998.1\|3485820_3486444_-\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|379312
NZ_CP045920.1\|WP_153879313.1\|3469109_3469862_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224051
NZ_CP045920.1\|WP_153879314.1\|3481328_3481808_-\|potassium-transporter-TrkA	unknown	unknown	gnl\|CDD\|223564
NZ_CP045920.1\|WP_153878989.1\|3473317_3473905_-\|dCTP-deaminase	unknown	unknown	gnl\|CDD\|234753
NZ_CP045920.1\|WP_153878991.1\|3475977_3476763_+\|MOSC-domain-containing-protein	unknown	unknown	gnl\|CDD\|225758
NZ_CP045920.1\|WP_153878986.1\|3469870_3470905_-\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223836
NZ_CP045920.1\|WP_153878990.1\|3473928_3475611_-\|glucose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|234679
NZ_CP045920.1\|WP_153878999.1\|3486658_3487528_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|213179
NZ_CP045920.1\|WP_153878992.1\|3476906_3477230_-\|AzlD-domain-containing-protein	unknown	unknown	gnl\|CDD\|377512

Protein	Function_ID	Function_description	E-value
NZ_CP045920.1\|WP_153878983.1\|3465970_3466735_-\|Asp/Glu-racemase	gnl\|CDD\|226004	COG3473, COG3473, Maleate cis-trans isomerase [Secondary metabolites biosynthesis, transport, and catabolism].	6.28628e-62
NZ_CP045920.1\|WP_153878993.1\|3477222_3477975_-\|branched-chain-amino-acid-ABC-transporter-permease	gnl\|CDD\|224215	COG1296, AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism].	1.05527e-30
NZ_CP045920.1\|WP_153878997.1\|3485308_3485764_+\|phosphoribosyl-ATP-diphosphatase	gnl\|CDD\|212137	cd11530, NTP-PPase_DR2231_like, Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Deinococcus radiodurans DR2231 protein and its bacterial homologs. This family includes a MazG-like NTP-PPase from Deinococcus radiodurans (DR2231), a putative NTP-PPase YP_001813558.1 from Exiguobacterium sibiricum and their bacterial homologs. DR2231 shows significant structural resemblance to MazG proteins, but is functionally related to the dimeric dUTPases. It can hydrolyze dUTP into dUMP. DR2231-like proteins contain a well conserved divalent ion binding motif, EXXEX(12-28)EXXD, which is the identity signature for the all-alpha-helical NTP-PPase superfamily. Unlike normal dimeric dUTPase-like proteins with a central four-helix bundle forming the active site, YP_001813558.1 displays a very unusual interlaced segment-swapped dimer. It potentially prefers to hydrolyze dCTPs or its derivatives. YP_001813558.1-like proteins contain a variant divalent ion binding motif, EXXEX(12-28)AXXD.	1.75247e-21
NZ_CP045920.1\|WP_153878984.1\|3466857_3467934_+\|hypothetical-protein	gnl\|CDD\|240652	cd12175, 2-Hacid_dh_11, Putative D-isomer specific 2-hydroxyacid dehydrogenases, NAD-binding and catalytic domains. 2-Hydroxyacid dehydrogenases catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-adenosylhomocysteine hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric.	7.47486e-90
NZ_CP045920.1\|WP_153878987.1\|3470901_3471825_-\|transporter-substrate-binding-domain-containing-protein	gnl\|CDD\|270225	cd01004, PBP2_MidA_like, Mimosine binding domain of ABC-type transporter MidA and similar proteins; the type 2 periplasmic binding protein fold. This subgroup includes the periplasmic binding component of ABC transporter involved in uptake of mimosine MidA and its similar proteins. This periplasmic binding domain belongs to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.91013e-63
NZ_CP045920.1\|WP_152909775.1\|3480111_3481326_-\|cation:proton-antiporter	gnl\|CDD\|223551	COG0475, KefB, Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism].	1.02897e-45
NZ_CP045920.1\|WP_153878995.1\|3479443_3480067_+\|TetR-family-transcriptional-regulator	gnl\|CDD\|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	1.9505e-05
NZ_CP045920.1\|WP_153878994.1\|3478110_3479352_-\|NAD(P)-binding-protein	gnl\|CDD\|223727	COG0654, UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion].	7.42568e-38
NZ_CP045920.1\|WP_153878996.1\|3481972_3485272_-\|hypothetical-protein	gnl\|CDD\|223627	COG0553, HepA, Superfamily II DNA/RNA helicases, SNF2 family [Transcription / DNA replication, recombination, and repair].	1.91267e-107
NZ_CP045920.1\|WP_153878985.1\|3468027_3468927_-\|transporter-substrate-binding-domain-containing-protein	gnl\|CDD\|270225	cd01004, PBP2_MidA_like, Mimosine binding domain of ABC-type transporter MidA and similar proteins; the type 2 periplasmic binding protein fold. This subgroup includes the periplasmic binding component of ABC transporter involved in uptake of mimosine MidA and its similar proteins. This periplasmic binding domain belongs to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	9.53293e-68
NZ_CP045920.1\|WP_153878998.1\|3485820_3486444_-\|methyltransferase-domain-containing-protein	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	3.96364e-18
NZ_CP045920.1\|WP_153879313.1\|3469109_3469862_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	7.78849e-145
NZ_CP045920.1\|WP_153879314.1\|3481328_3481808_-\|potassium-transporter-TrkA	gnl\|CDD\|223564	COG0490, COG0490, Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels [Inorganic ion transport and metabolism].	5.42084e-44
NZ_CP045920.1\|WP_153878989.1\|3473317_3473905_-\|dCTP-deaminase	gnl\|CDD\|234753	PRK00416, dcd, deoxycytidine triphosphate deaminase; Reviewed.	4.35294e-92
NZ_CP045920.1\|WP_153878991.1\|3475977_3476763_+\|MOSC-domain-containing-protein	gnl\|CDD\|225758	COG3217, COG3217, Uncharacterized Fe-S protein [General function prediction only].	4.83994e-29
NZ_CP045920.1\|WP_153878986.1\|3469870_3470905_-\|ABC-transporter-permease-subunit	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	1.02785e-74
NZ_CP045920.1\|WP_153878990.1\|3473928_3475611_-\|glucose-6-phosphate-isomerase	gnl\|CDD\|234679	PRK00179, pgi, glucose-6-phosphate isomerase; Reviewed.	0
NZ_CP045920.1\|WP_153878999.1\|3486658_3487528_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|213179	cd00267, ABC_ATPase, ATP-binding cassette transporter nucleotide-binding domain. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	7.95544e-12
NZ_CP045920.1\|WP_153878992.1\|3476906_3477230_-\|AzlD-domain-containing-protein	gnl\|CDD\|377512	pfam05437, AzlD, Branched-chain amino acid transport protein (AzlD). This family consists of a number of bacterial and archaeal branched-chain amino acid transport proteins. AzlD is known to be involved in conferring resistance to 4-azaleucine although its exact role is uncertain.	0.00470025

>NZ_CP045920.1|WP_153878991.1|3475977_3476763_+|MOSC-domain-containing-protein
MPHVAALYRHPIKGFTPESADHLDVQTDGRIAGDRVLAFRFPDALSPEDRDGLDYWPKGGGLCVRDFPSLVRLRLRHAAGRVRLEAGGEVLAEERVDDAGRLRLTAAVTRFLAGTEDADRLERFGPLTLVGDGRSARFQDRPQGFVSAHSRSSRDALAGAMRTDLDERRFRSNVSVAGLPAWAEDDLIGRRVRLGEVRFAVHAPINRCLATHANPVSGERDAPVLTTLTRVLGRPQPSFGILLVADGPGRISVGDPVEVLG
>NZ_CP045920.1|WP_153878990.1|3473928_3475611_-|glucose-6-phosphate-isomerase
MTASIDPTTTPAWAALSAHAENLRPDLRGWFAADPGRAARFTREAGDLWVDLSKNLLTPDTLRLLLDLAEQTRVTARRDDMFAGAHINTTEDRAVLHTALRRPAGAGEPLVVDGQDVDADVHAVLGRLYDFAGRVRSGEWTGVTGKRVETVVNIGIGGSDLGPVMAYEALKPSVQLGLQCRFVSNIDPTDISEALWDLDPETTLFIVASKTFTTLETLTNARLARTWLLEKLHERGVIEANEESYTGAVSQHFVATSTALDKVAEFGIDTANAFGFWDWVGGRYSVDSAVGLSLAIAIGPENFADFLAGFATIDDHFRTAPPAENLPLLMGLINVWYVNFLGAHTHAVLPYSQYLHRFPAYLQQLTMESNGKGVRYDGAPVAAHTGEVFWGEPGTNGQHAFYQLIHQGTRIVPADFIAVANPAHALADGDQDVHHLFMANYFAQTKALAFGKTADEVRAEGTAEEIVPARVFTGNRPTTSILAPELSPGVLGQLIALYEHITFVQGAVWGIDSFDQWGVELGKQLAQQITPALSGDAAALDGQDASTKAAIERYLAERRP
>NZ_CP045920.1|WP_153878989.1|3473317_3473905_-|dCTP-deaminase
MLLSDRDIRTEIAAGRIRLDPFEPEMVQPASVDVRLDRYFRLFDNHKYSVIDPAAEQPELTRLVEVDPEESFTLHPGEFVLASTLEVVTLPDDLAARLEGKSSLGRLGLLTHSTAGFIDPGFSGHVTLELSNVATLPITLWPGMKIGQLCYFRLTSASELPYGAGATGSRYLGQRGPTASRSHLNFHRTRITPDE
>NZ_CP045920.1|WP_153878988.1|3472362_3473313_-|hypothetical-protein
MTAIHLLLLAEDVSAAELEALALSRVHQVFRPDPRTLAWSGAVTCTGPRPPAPADHVPGWVRHVVEFRVPAERGGPIPPELRTAGSILAAFPDGEPIGLERDTVELIMAFARRLGGAVRTSTGRLVGAPPIPDLLLFSDTRLEPAAARAALAPFVTVRGDDAAGPPPRPTVPEVVEHGLDDGHRRWLHAEADAFDAHALAEPGPGSESYSVHAPQADGGLVVLTVDEAPVTPIVVADAAWAGATAYVYEVRYYAPPPVPELEPQERAAWLAAQEESLANPAVVAVIENCAWAVRSALGGVERAIVCDDDGFLVTLG
>NZ_CP045920.1|WP_153878987.1|3470901_3471825_-|transporter-substrate-binding-domain-containing-protein
MQRKFLTVGHRTLAVTAAVCLLGLGACSVDGAEAEAGPDGPSEGGTSGSGESSSELAAMLPSDVRDDGVISWGVEPYYPPFTMSEDGGTDVIGINVDLAEELSALLGVEAEVLPGSFDGLIPGIQSERYDVGIATMADTEERREQVDFIDYFQSGSAIFVKPGNPLNIEGMNDLCGHSVGVVKGTFQVIDAETQAELCDTDGAGKLDVQVFNEQAGMLLALSSGRTEVMLMDYVAGSYAATTEGGEQFEMTGEIETPQRKGMIVSPERSELRDAVQAAMQARRERSVFGDPRGVGSGERRSRNDHDQ
>NZ_CP045920.1|WP_153878986.1|3469870_3470905_-|ABC-transporter-permease-subunit
MTETETQAMMKSQAPPHTARSAQEAEELRGGPPEADVGTFQMIPRRRYGRWVGAALILWLFVLVVNSLARNPRMEWGVVREYFFSTSVVTGLLHTLNLTFWIMVLGILLGTVLAIMRHSGNPVLVAVASFYVWVVRSLPPLVQLLIWYNLAAVYPEITVDLPIVGQVFSGSANDFITPFTAALLALGLNEGAYMGEIIRSGISSVDPGQVEAAKGLGFSGAKTMRRVILPQSLRVIIPPTGNELITVLKVTSLVSIISMTDLLYSVQLIYSKTFQTIPLLVVACIWYLIVTSFLAVFQGTLERRLAPERTVGTTTWSQRMLSGVNRLTAVSGRAGRRSDEGGSK
>NZ_CP045920.1|WP_153879313.1|3469109_3469862_-|ATP-binding-cassette-domain-containing-protein
MVDARKVRKSFGSNEVLKGIDFQVEAGKVVCLLGASGSGKSTFLRCINHLERINGGVLYVDGSPVGFRQKGTKLYELKEKEIARDRAEIGMVFQRFNLFEHRTALENVIEAPIQVRKVERAQAVARAEELLARVGMADKASSYPRHLSGGQQQRVAIARSLAMQPKLMLFDEATSALDPELVGEVLDVMRQLAAGGMTMIVVTHEINFAREVADEVVFMDAGVVEEQGPPAEVLGNPQSPRTQSFLAKVL
>NZ_CP045920.1|WP_153878985.1|3468027_3468927_-|transporter-substrate-binding-domain-containing-protein
MRLESMKTKGRRATLMVVVALAASACGGVPESDPVADRTAAARGPSALLPDDVREDGVIHWGVEPYFPPFTMSGDDDQTVVGINVDLADELSAVLGVESDVIPGSFDGLIPGIQSERYDIGIATMADTAERREQVDFIDYFENGSGIFVRIDSPLGIEHLADLCGHVVGVVKGTYQVGDAEDQADRCADDGLGQLEVQVFNEQAAMILALTSGRTEAMLMEDVAGLYAATAAGSEFEITGEVQDPKRSGMIVSKDRPELRAAVQAAMQQLMDRGRYLEILESWGQEGGAIGVATLNDAR
>NZ_CP045920.1|WP_153878984.1|3466857_3467934_+|hypothetical-protein
MLPTGLLRVSARRGQSRPRTTELAMPLPVILSTSPRSIVEGPYQRRHASMSPHELRYSSRDPKQLARDLAEADLILGDWTAELKLDRHALDAANRSRIVVHPTAGYDSIDVTHAAALGLPVANTPGANARGVAEWAVMAALACLKNLTLNHQRTRAGEWRMVEASAEGVYDVGGRTIGILGFGAIGQGVARRLHAFGVDRILYFDAFVDVDSIDGGAPVERVQSVAELCERADVVSIHLPLTPETRHIVDAENLRRIGTDGVIVNTARGQVVDEDALHAALVAGTIKAAALDVFSDEPLIGAHRWADLENVLLSPHLAGSTHESKQQMLDGALRSLDAALRGDLPRSVVNQVTSLRLL
>NZ_CP045920.1|WP_153878983.1|3465970_3466735_-|Asp/Glu-racemase
MTPQFQPDRYGTRARIGLVYMASSVVMEPEMYAMAADDVSIHTSRLTLPSVTVDGIDAMMRSPELESAVRLCGQAPLDSMVFGGTSASFLHGTAWDQALIEKMTEWSPVRSTTTSTASLAALAEVGASKIALVTPYVPEVVHRAEKFFGSNGFPVQRSLGLGITSDWELAEVPLEQVYDMCLEVDGDDISAIFISCTNLRSVGAIAAIEQAIGKPVVSAIQASFWHCLNVAGVEGGAAPGYGRLFDAKMEQVRQ
>NZ_CP045920.1|WP_153878992.1|3476906_3477230_-|AzlD-domain-containing-protein
MGELTQILLGGLLLGIGTYAMRAGGGEIGDRIAAYPRFQLAVEDAAMLILASVMATSALTDGQSFAGWARPAGVALSGLLAWRGAPLPIVLLVAAAATAGLRALGIA
>NZ_CP045920.1|WP_153878993.1|3477222_3477975_-|branched-chain-amino-acid-ABC-transporter-permease
MGAAAGRRDVDTIRAVVLLGCAMALVGVAYGAMTVGVGLPVWVAPVLGVIVLAGSSEMLYVGLATATSPWLALPAALLVNVRHVPYGMAVRRYLGHGRTRAWRSHVMNDESVAFALAEREPERAKRTYGLAGIAVLISWPTGAFVGGLLGRGIDQEAFGLDAIFPAVILALVLPALKRARMRPAIVVAVLVSVPAALLLPQGLGPIAGLLALPLAVWRTRDALAQRAGEEGAAGTGPAVPSGRAEDGADG
>NZ_CP045920.1|WP_153878994.1|3478110_3479352_-|NAD(P)-binding-protein
MIVETPAADQLDRADPGEPRILVVGAGIAGTTLAQLLRRAGRHPVLIERHDADAHADRGYMLALMSMVDPALDELGAGADYRRRSQRFDRYRIHSHRGRVLRTDPIAGLLDRYGDYRGIDRGALLDCLAGATVTCEVAHGTTVSAVERGDDAAPLRVCLAGARPAELEVDLIVAADGIGSTTRGLLHDGEPVDSVDTGWGGWVVWARPDADPGLGSELWGDGFLVGAYPVLGALGAFLGGPRAIRDAGPAAYAERVRRALRVVPERIDRVLTALVDDPDPFWWPLVDARAGSWVRGRSVLLGDAAAGFLPTAGIGAGMAIESAWVLARHLTHAHAHAPGAADLDGRLAAYERAQRPRVTAAHDTSRRLATLMCRTSLPLAVARDVVMRFVSIDLALRPIQQLLAHPPDLPAPR
>NZ_CP045920.1|WP_153878995.1|3479443_3480067_+|TetR-family-transcriptional-regulator
MSSDRMPPERRARLVRVAATEFAAGYEAASLNRIIRECGLSKSSFYHAISSKRELFDLVVDDLAAAVSAAVPLPTPESLGSADSPAGAPGGDFWGGARALMGTLVEAATRVPTFAALGALFYVSDAPTGSRLTELDRAIDAWVGRALELGRASGAVRTDLPTDLQYRLALAALRALDRWSLEHLEEVVGAGALAEAQLDAVRRLLEP
>NZ_CP045920.1|WP_152909775.1|3480111_3481326_-|cation:proton-antiporter
MSSARGLLELGAIILGLGLLGRLAALVRISPIPLYLLAGLVFGVGGLLPLATSEAFVSVGADVGIILLLLMLGLEYSADELLANLRTQSPAGVVDFVVNAAPGALVGMLLGWPAAGIVAMAGVTYATSSGIVAKLLTDLGRLGNRETPVVLSLMVFEDLLMAIYLPVLTALLLGVGVVGGTISVVGAVVAVALVMFVALRWGRFINRLLFSASDELLLLGLLGFVLIVAGFAEELHVSTAVGAFLVGIALSGQVAESARLVLSPLRDLFAAVFFVFFGLRTDPAEIPDVLGVALALALVTILTKVGVGGWAARRAGIARPGQLRAGAMMVPRGEFSIVIAGLATSAGIAGIGPLAATYVMIMAVVGPILARLAEPVARRIAVVAKRREARRADPGEPGAAREEA
>NZ_CP045920.1|WP_153879314.1|3481328_3481808_-|potassium-transporter-TrkA
MEVNEAPLPGIGLRDDFRTVAGRRIGVVSHHTGRRDLVIYAEDDPDACVETVALTPAEADTLAEFLATRRVTERLARLTEQVAGLQTAKVPISAGSRFGGDTLGGTEVRTRTGASIVAVLRDREAIPSPTPDFELAAGDQLIVVGTQEAIAAVDEIING
>NZ_CP045920.1|WP_153878996.1|3481972_3485272_-|hypothetical-protein
MADPLPLIDVDAVRARVDRGSFDRGEQYAGQGAVAGLTWSSEHGVLTSVVLGNSAAPYRCRVDLERGDGAWSPAFMACSCPVGSACKHAVATMLSCHWRALESGPGPDSNAAGGEGAIADSWRGRLAGIGGAEARDRSPLALGFALRADRFASVRPVRELVAAGEALALTVRPLRRGKSGAWIKGNLTWRTLAHQIHRLSLDPDQLLWFSQLLGLYDATRTSYAGVDTEGLPLADFRSPLLWTLLADAEQLGIELVGLDRAVTVSVAAGAGAVVEWTALPGSHGGLRLEPRVGVEGRELATWSPIGDHGLWAARLEDRSVRVVLTPTATPFGAEQRRLVEAGALEIPPADVPEFYATYYPRLRSAMPVRSGDDAVTLPPIEPATLRLAAAFRSRNRVTLTWQWHYHDPPRLLPFEPEPGPAPGPAPGSALAGPRDRAREAELVAVAESLWPGGTGRATHELTDVSTAEFTTRILPALERQAGLEVEVLGRRPAFEELTGAPSVTVTTVETERTDWFDLGFLITVEGREIPFVRLFEALSRGRKKLLLVDRSYFSLEHPAFDQLRELLAEAEALPEWEPDRPRLSRYQVDLWADFEDLADETVEARSWRESVAGLRDLDSIEARPQPDSVRAVLRPYQLDGFRWLAFLWRHRLGGILADDMGLGKTLQTLSLIAHARTGGDAAAGGQVDPPFLVIAPTSVVSTWLNESARFTPQLHALAITATRGKRGTSLAQEVAGADLVVTSYAIARLDAEEFTAADWSGLVLDEAQFVKNPATRAHREIARIRAPFRLAITGTPLENSLTDLWALASLTAPGLFPSARRFREEYVRPIESGAMPERLDRLRRRLRPFMLRRAKEAVARELPPKQEQVIRVDLSARHRQLYDTTLQRERQKVLDLVEDLDRNRFIVFRSISLLRMLALAPELIAPEHAGLGSSKLDALAEVLPGIVAEGHRTLVFSQFTSFLRMAADRCEALGIDYVYLDGSTRSRPKVIEGFRSGAAPVFLISLKAGGFGLTLTEADYVFMLDPWWNPATEAQAVDRTHRIGQTKNVMVYRLVAEDTIEEKVMALQRRKAALFSAVMDSEEPFARALTAEDVRGLFD
>NZ_CP045920.1|WP_153878997.1|3485308_3485764_+|phosphoribosyl-ATP-diphosphatase
MTDPADLVSRFHATYSLPVRQGPPTADLERIHLRMALVAEEFAELVGAVYGEAAEAGMVEAFERARAADAGTRDVVATADALGDLVYVIYGMALECGIPMDRVLAEIQASNLSKRGAGGEPILRADGKVLKGPDYFPPRIDRVLAEAADPS
>NZ_CP045920.1|WP_153878998.1|3485820_3486444_-|methyltransferase-domain-containing-protein
MVEKSRWETMVTENPDHSRWFVERFRAKAAAGEDVSGEARLVDALVPRAARILDAGCGSGRLAPHLLAQGHTVVGVDVDPVLIEAARADHPGGTWIVGDLAELDLPAAGVPAGFDAIVAAGNVMPFLAPSTRVGVLSRLRDHLAPGGRIATGFGAGRGYLIEDFLTDVGAAGLDVESRYESWDLRPFTPESGFLVAVLTRGRSGRPR
>NZ_CP045920.1|WP_153878999.1|3486658_3487528_+|ATP-binding-cassette-domain-containing-protein
MSPESPAEPAEPTEAIGPDSPIEASAPTEASAPTEADAPAEPTDPTEADEPAGPDAPTEPEEPAEPAEPEAPVEPQPAVRLEGAGLRSGRGWVFRDVSFTAHTGTTTTLTGPSGSGRSTALLACAGRLDLTTGSAAVHPPRRRVRDHVNVARIAGVIGLDPQLSVADNVNDAADWARLRRTQARDLLATWRSRLDLQLPSRLPAGELAADELTLLHLLCATLGNPRAIVLDDFDANLTIPQIARLWKLTARVAAGRVSAPVAVIVSTVAALPPAGERVIHLGDANGAAA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP045920_14

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045920_14

3503339-3503424

Orphan

Consensus_repeat	Method
CGGCCGTCCGCGCACCCGCGGCTGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045920_14

>merge|NZ_CP045920|14|3503339-3503424|CRISPRCasFinder
CGGCCGTCCGCGCACCCGCGGCTGCGTGTTCGCACGCTGGATTCGACGCCGTGTCCCCGTCCGGCCGTCCGCGCACCCGCGGCTGC

>NZ_CP045920|14|12|3503339-3503424|CRISPRCasFinder
CGGCCGTCCGCGCACCCGCGGCTGC	GTGTTCGCACGCTGGATTCGACGCCGTGTCCCCGTC
CGGCCGTCCGCGCACCCGCGGCTGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045920.1\|WP_153879011.1\|3510361_3512314_+\|potassium-transporter-Kup	unknown	unknown	gnl\|CDD\|376906
NZ_CP045920.1\|WP_153879005.1\|3501806_3502574_-\|type-I-methionyl-aminopeptidase	unknown	unknown	gnl\|CDD\|238519
NZ_CP045920.1\|WP_153879004.1\|3500538_3501531_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045920.1\|WP_153879013.1\|3515842_3516736_+\|DUF58-domain-containing-protein	unknown	unknown	gnl\|CDD\|224635
NZ_CP045920.1\|WP_153879012.1\|3514764_3515811_+\|AAA-domain-containing-protein	unknown	unknown	gnl\|CDD\|223786
NZ_CP045920.1\|WP_153879008.1\|3504711_3505518_+\|dienelactone-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223489
NZ_CP045920.1\|WP_152909788.1\|3508060_3509077_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224093
NZ_CP045920.1\|WP_153878999.1\|3486658_3487528_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|213179
NZ_CP045920.1\|WP_153879003.1\|3492993_3494790_-\|copper-binding-protein	unknown	unknown	unknown
NZ_CP045920.1\|WP_153879002.1\|3491823_3492804_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224224
NZ_CP045920.1\|WP_153879316.1\|3499009_3499960_-\|multicopper-oxidase-domain-containing-protein	unknown	unknown	gnl\|CDD\|259991
NZ_CP045920.1\|WP_153878998.1\|3485820_3486444_-\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|379312
NZ_CP045920.1\|WP_152909787.1\|3506510_3508064_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224053
NZ_CP045920.1\|WP_153879009.1\|3505524_3506349_+\|DUF2993-domain-containing-protein	unknown	unknown	gnl\|CDD\|378597
NZ_CP045920.1\|WP_153879315.1\|3494950_3498862_-\|DUF1080-domain-containing-protein	unknown	unknown	gnl\|CDD\|377643
NZ_CP045920.1\|WP_153879317.1\|3512478_3513984_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378238
NZ_CP045920.1\|WP_153879007.1\|3504048_3504654_+\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP045920.1\|WP_153879010.1\|3509194_3510196_+\|substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|380660
NZ_CP045920.1\|WP_153879001.1\|3489575_3491861_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379601
NZ_CP045920.1\|WP_153879000.1\|3487524_3489465_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274413

Protein	Function_ID	Function_description	E-value
NZ_CP045920.1\|WP_153879011.1\|3510361_3512314_+\|potassium-transporter-Kup	gnl\|CDD\|376906	pfam02705, K_trans, K+ potassium transporter. This is a family of K+ potassium transporters that are conserved across phyla, having both bacterial (KUP), yeast (HAK), and plant (AtKT) sequences as members.	0
NZ_CP045920.1\|WP_153879005.1\|3501806_3502574_-\|type-I-methionyl-aminopeptidase	gnl\|CDD\|238519	cd01086, MetAP1, Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.	2.56277e-108
NZ_CP045920.1\|WP_153879007.1\|3504048_3504654_+\|TetR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	8.63111e-17
NZ_CP045920.1\|WP_153879013.1\|3515842_3516736_+\|DUF58-domain-containing-protein	gnl\|CDD\|224635	COG1721, COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only].	1.34032e-19
NZ_CP045920.1\|WP_153879012.1\|3514764_3515811_+\|AAA-domain-containing-protein	gnl\|CDD\|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	5.67385e-82
NZ_CP045920.1\|WP_152909788.1\|3508060_3509077_+\|ABC-transporter-permease	gnl\|CDD\|224093	COG1172, AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism].	9.12122e-82
NZ_CP045920.1\|WP_153878999.1\|3486658_3487528_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|213179	cd00267, ABC_ATPase, ATP-binding cassette transporter nucleotide-binding domain. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	7.95544e-12
NZ_CP045920.1\|WP_153879002.1\|3491823_3492804_+\|hypothetical-protein	gnl\|CDD\|224224	COG1305, COG1305, Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism].	3.45804e-31
NZ_CP045920.1\|WP_153879008.1\|3504711_3505518_+\|dienelactone-hydrolase-family-protein	gnl\|CDD\|223489	COG0412, COG0412, Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism].	5.40665e-34
NZ_CP045920.1\|WP_153878998.1\|3485820_3486444_-\|methyltransferase-domain-containing-protein	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	3.96364e-18
NZ_CP045920.1\|WP_153879316.1\|3499009_3499960_-\|multicopper-oxidase-domain-containing-protein	gnl\|CDD\|259991	cd14449, CuRO_1_2DMCO_NIR_like_2, The cupredoxin domain 1 of a two-domain laccase related to nitrite reductase. The two-domain laccase (small laccase) in this family differs significantly from all laccases. It resembles the two domain nitrite reductase in both sequence and structure. It consists of two cupredoxin domains and forms trimers, and hence resembles the quaternary structure of nitrite reductases more than that of large laccases. There are three trinuclear copper clusters in the enzyme localized between domains 1 and 2 of each pair of neighbor chains. Laccase is a blue multi-copper enzyme that catalyzes the oxidation of a variety of organic substrates coupled to the reduction of molecular oxygen to water. It displays broad substrate specificity, catalyzing the oxidation of a wide variety of aromatic, notably phenolic, and inorganic substances. Laccase has been implicated in a wide spectrum of biological activities. This subfamily has lost the type 1 (T1) copper binding site in domain 1 that is present in other two-domain laccases.	1.5452e-49
NZ_CP045920.1\|WP_152909787.1\|3506510_3508064_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	0
NZ_CP045920.1\|WP_153879009.1\|3505524_3506349_+\|DUF2993-domain-containing-protein	gnl\|CDD\|378597	pfam11209, DUF2993, Protein of unknown function (DUF2993). This family of proteins with unknown function appears to be restricted to Cyanobacteria.	7.58184e-07
NZ_CP045920.1\|WP_153879315.1\|3494950_3498862_-\|DUF1080-domain-containing-protein	gnl\|CDD\|377643	pfam06283, ThuA, Trehalose utilisation. This family consists of several bacterial ThuA like proteins. ThuA appears to be involved in utilisation of trehalose. The thuA and thuB genes form part of the trehalose/sucrose transport operon thuEFGKAB, which is located on the pSymB megaplasmid. The thuA and thuB genes are induced in vitro by trehalose but not by sucrose and the extent of its induction depends on the concentration of trehalose available in the medium.	2.42996e-34
NZ_CP045920.1\|WP_153879317.1\|3512478_3513984_-\|hypothetical-protein	gnl\|CDD\|378238	pfam09678, Caa3_CtaG, Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG). Members of this family are the CtaG protein required for assembly of active cytochrome c oxidase of the caa3 type, as found in Bacillus subtilis.	7.33023e-78
NZ_CP045920.1\|WP_153879010.1\|3509194_3510196_+\|substrate-binding-domain-containing-protein	gnl\|CDD\|380660	cd20005, PBP1_ABC_sugar_binding-like, monosaccharide ABC transporter substrate-binding protein such as CUT2. Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems that share homology with a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein superfamily, which consists of two domains connected by a three-stranded hinge. The substrate specificity of this group is not known, but it is predicted to be involved in the transport of sugar-containing molecules and chemotaxis.	5.39602e-128
NZ_CP045920.1\|WP_153879001.1\|3489575_3491861_+\|hypothetical-protein	gnl\|CDD\|379601	pfam14403, CP_ATPgrasp_2, Circularly permuted ATP-grasp type 2. Circularly permuted ATP-grasp prototyped by Roseiflexus RoseRS_2616 that is associated in gene neighborhoods with a GCS2-like COOH-NH2 ligase, alpha/beta hydrolase fold peptidase, GAT-II -like amidohydrolase, and M20 peptidase. Members of this family are predicted to be involved in the biosynthesis of small peptides.	1.06698e-128
NZ_CP045920.1\|WP_153879000.1\|3487524_3489465_+\|hypothetical-protein	gnl\|CDD\|274413	TIGR03061, hypothetical_protein_lp_1332, YhgE/Pip N-terminal domain. This family contains the N-terminal domain of a family of multiple membrane-spanning proteins of Gram-positive bacteria. One member was shown to be a host protein essential for phage infection, so many members of this family are called "phage infection protein". A separate model, TIGR03062, represents the conserved C-terminal domain. The domains are separated by regions highly variable in both length and sequence, often containing extended heptad repeats as described in model TIGR03057.	9.25722e-57

>NZ_CP045920.1|WP_153879005.1|3501806_3502574_-|type-I-methionyl-aminopeptidase
MIELKTPAEIDEMRPAGAFVASVLDALLKKAAVGVGLFELDALAHRMIREAGAESCYIDYHPSFGASPFGKVLCTSVNDAVLHGLPHDYTLADGDLLSVDFAAKLNGWVADSAVSMIVGAPRAEDQRVITATEEALQAAIEAARVGRRVGDISAAIGAVAADYGYGVNTDFGGHGVGRTMHGEPHIPNNGRAGRGLPLRPGLTIAIEPWFMIGTAELFTDADGWTLRSADGSRGAHSEHTIAITHDGPVVLTARD
>NZ_CP045920.1|WP_153879004.1|3500538_3501531_+|hypothetical-protein
MKKRLTTVLIGGMAIAGFGAVGPAPAQAALTTHCVGEADGVTVPGDLLIPRGKACSLTDITVTGDVRVAAGADLVADGLTVEGRIVVQSDGYLDLTGSTVAGNVVNRGSFGVYLDDTDVRAYTATANVNPDTFLWTDEAEFSGRIAATGGSFLLESSTADRAVQTTDTQYTDIIDSVVGGTLTVTGAEFGAMVCGSEVDRHATFASTGVGVQLGAGGALADCDLGPSVWGGNVLVSGTTGAVQVSDNIIRGNLDGTGNDSVTASDNRVRGDLKGQFAEQAARPMMRMQLDAAPTLERGDASAERDALEQLRDDRLGIAEQLAEEAGPANL
>NZ_CP045920.1|WP_153879316.1|3499009_3499960_-|multicopper-oxidase-domain-containing-protein
MLAGAAAAVLTPAAVALTGTSALGAPGGRGAGETHRITMYAEDLGDGRVGYGLAPGEATIPGPVLEMYEGDTMEITLVNTTDRSLSIHPHGVLYETTSDGSPFNDSFNGPGETRTYVWRTTTETSMGRVSRPGSAGYWHYHDHAMGTPHGTGGLQAGLYGALIVRRRGDVLPDRQFTVVFNGMLINNASAPHTPMFEARLGETVEFICIGHGDMFHTFHLHAHRWANTRTGYLEGPRDSSEVIDNKDLNPGSSFGFQVVAGEGVGAGAWMYHCHVQFHSDGGMAGVFLVRNEDGSMPAGAQAAIDRFHEHEGGHGN
>NZ_CP045920.1|WP_153879315.1|3494950_3498862_-|DUF1080-domain-containing-protein
MATMNVAPAIAGPPGQAEAARSGDAVVTANEEATPTGDVEVLVFHGDPAEQDDPVLEAANTIAELGAANGFSVTSTSDPADFTDENLDGYRGVVFLSAVGSELDGDQEGALEEFINDGGGFLGIRDAAKAQESSQWFTGLVGARPAGIRPTPEEVADVTATGENPPRETAANLTDGDENTKWLAFDDVATVTYELVEPAVITEYAMVSANDFPGRDPGAWTVRGSTDGESWTDLDTRSDDFSQRFLRKSYEIDNSTEYQYFQLEVRENGGESATQLADWLLFTEEAVNPPDVEVPTQEATVNVVDRLHVANEGLPLNWTRSDKWYNWETNPIGRVHTIAQVQEWDYDAGDTANGAFHPISWCRDYDGGRSFYTGMGGTAESYSEDGFRSHLLGAIQWSTGIVRADCQATIGSNYEIERLTTQNSPGELDQIGEPHGLVTTDDGTVFYVGRGACATGAIPSWDAENVGLGCGTIHQWDPDTGEATLLTVLDVFGNRGSGGELVKTEEGLFGIEPDPDFAENDWLYVYWMPYDSIDTENRTGMRTVSRFTYDRENVTIDQDTRVDLLEWQTQIHSCCHAGGGMAFDDDGNLYVSTGDNNSSQGSSGYSGNNWTQEYAGISFQDARRTAGNTNNLNGKILRIHPEEDGTYTIPEGNLFTGEEGGGDKARAEIYVMGVRNPSRIQIDADTDWLTAAWVGPDAFLPDPELGPAKYETATIITSAGNQGWPYCMGNRQPYRDRSNEDASILTDWYDCDDLENNSPRNTGLVDIPDARDNMIWYSPSGGGPDFPRDENGIPSYEEDEATYSEPYLRGGGQAVMSGPTYRSSQVDSGSDIAWPEYWEGKWLIGDQSNPNNRMAITVDPDAVDEAAPPVFAEDLRQIIRAGGGDNQLQSWMDAEFGPDGALYMLDYGSGFFTLHQNQKLIRIVYTGGPATPAPAATATSIQSSPLTVQFNGSRSGGVAWEWDFGDGTTSTEADPRHTYDRVDSYEATLTVTYADGTVETVGTDAVIECAVPDSRDTVWIGDEDTGVTNTDLGGCTIADLIDDEGEWDNHGAFIRHVNDVIRQLRDNDVISGRDIGRLTNGAARSDVGTPGDAGYRWLFDGTSASLDGWRQAPGGHFELLPGGSLLSQGGLGMLWYEAEEFEDFSLKLQFRDVSEGTTYANSGVFVRFPDPTAQDQPECGRGQSQAWVAISCGHEIQLYDGPTGEPQKTGSVYNFEPVAREDAGLTEKGVWNDYEIRVVDQHYTIVRNGVVINEFENAPGKESSRAGDPPTDLRQFERGFIGLQNHSNSDRMEFRNIRVQDLS
>NZ_CP045920.1|WP_153879003.1|3492993_3494790_-|copper-binding-protein
MLRRLVIGLLSAMIGLFIVPTAATAQQQVLTWTAGNSVTQYLSAPATAVAGTATVIFDNSRAAGNTTGMPHTLTFDTTTPGYNHDVDLNITANPYDENGGYYEAEITLTPGTYRYHCVIPGHGMMVGELVVTADGGDPDPDTTAPEVAAAVTGQQDDDGDYLGSAEVAITATDAGSGVDAVEYSLDGGEFLAYDGPVAVTEIGGHTVDYRATDVAGNTAEGSVSFAIVEDADPDTTAPEVAAAVTGEQDDDGDYVGSAEVAITATDADSGVAAIEYSLDGGEYTHYHMAVVVAEVGGHTVDYRATDVAGNTAEGSVSFTIVEEAGPDPDTTAPEVGAEVAGERNDDGDYVGSVEVAITATDAGSGVDVVEYSLDGGEFLAYDGPVAVAEVGGHTVDYRATDLAGNTAEGGVSFTIVEEAGPDPDTTAPEVGAEVAGERNDDGDYVGSVEVAVTATDAGSGVDVVEYSLDGGEFVAYDGPVAVTEVGGHTVDYRATDVAGNTAEGGVSFTIVQEGEPGDCPDGRATVTIDGIDTGVANADLGDGCTINDLIDEAGDYENHGQFVRHVGDVVRPLADDGILTQREVGAILRAAARSQIGR
>NZ_CP045920.1|WP_153879002.1|3491823_3492804_+|hypothetical-protein
MRCCGPGEATMTEGVFFAITHRADQRYRRPVTSAYGRLLLTPRAGGGQRVHAAAVTIDPEPDRRQVRRDFHGNMSTFIQLTQPYDRLTISAESIVELTRRPPDPASLPRLSWEHTAQAVRTVLDAEGTGHAGSVSAALAVAESRLGSPLVTPSEEFREFAAPSFRPGRPLVDVAGELSMRVAGSVRIVPTARAGPQGASTALREATGTVNDAAHLLLAAARSMGLAARYLTGYRFDQASGAGELHAWASLWVPGGGWIHVDPSRGGFVDLDYVALGWGRDAWDVLPLRGVAYGSELAGRPEVEVTMRSLSPEEAAELAVGVRTGSR
>NZ_CP045920.1|WP_153879001.1|3489575_3491861_+|hypothetical-protein
MTNLLAAYQAGTRPPAAAHDELLDASAAARSAWDLLATDPGLSSPAALAQRQADLTGILVEEGVRAGVADIRDWTLDPLPVILDEQEWQHLAAGLAQRAELLDAILTDLYRERRLLTEGVLPAELVLGHPGFLRAADGIRVPGPHQLFMTGSEIARRDDGTWLVTEIGTDLPRGLGFALTTRRAVSRVLAEGYRHMPIRRVGPFFRTVRDSLGALAPHGAKRPRMAMLVPQPPGLDQLHLADALGLPVVDAGDLHMADGRVWMRSVGDMEPVDVLLRQVDSARSDPVDLYSQSVSGVPGLLEAAHHGAVSVVNPIGSAVLENPALLSYLPAAARTLLSQELLLPSVPTHWCGEREMGSHVIAHLHELVVTCTSTGHQYRGWELSTAERTDLAVRIAAMPHDWVGQEPVELATTPMLGPLGLTPAVTSIRTFTVATAAGFEVLPGGVATTGPLPGRLTGSGHAKDVWVLSATPPDDALEPGLLTGPIPLSAASAGSLFRFGVLLERTEAQLRRQRAAVEDEAALTGLIDAAPEATAAALGRLGRAAQAVREHLTPEAWRTLTMLDEPGAIADRLVAMAAFSGVLAESVVRDDGWRALDMGRRLARSEFLVTSVAAVLVTPADYSLEADRIAALARMHDIALSHRRQSHEHPPLPALLDLLLADRTNPRSLTYSLERFGEDLERLPRPHEASGVVQEQLSSILRELTREIDGAWLAEADSTGRLRHLEDLTESVRWRVGALMSTLDRWSPADAVLWSGGGDDD
>NZ_CP045920.1|WP_153879000.1|3487524_3489465_+|hypothetical-protein
MRTLRLAMTEITRHHRPLHRLAVLFLLIVPSLYGALYLWSNWDPYGRLDDVPVAVVNHDVPVTVDGTEVAAGDQLVENLFADPVFGWELTDEASAADGLARGDYYLTITIPATFSADLASGAEGTPRRAVVDMRRDDANGFVVGIMAETVQKQLHDQINSAATQAYFESVYGDLDALRGGLVQLQDGAHDLAAGLTDAVDGSAELAGGLTDAVDGSAQLADGAAQVADGTQQIADVINPVADVIAPAIPGIAAESEDLAGSAAELTGLVSGAGDTLHSRTEAVTGALTDYLAAHPEAGEDPLFAAVTDAATRVEERTGEIAGVADDVDEGARTIHDATREIVAAAPNLQAEVTDGRARINDLNDGAHQVADGAAELASQLRPARDGAGELAAGLAGAGPGSADLAAGVDHLVAAVPALDPQTREANAQILGNPTEVNLAVDNPAHVYGRGLAPFFFAIALWVFGIVVFLVLRPTTGRALASPANPVRIQLVGWLPILGLGLVGSYLLLAISWFALGLDPVDPAGSVLVVTVTVALFTLIAHLARNALGLVGSAVLLVLLMLQLISSAGIYPVETLPGLLQAIHPYLPMSYVVDAFRIVFTGGSGAKLAQDLAILAGLAAVVFAAGALLVARKRTWSLLTVHPPLAE
>NZ_CP045920.1|WP_153878999.1|3486658_3487528_+|ATP-binding-cassette-domain-containing-protein
MSPESPAEPAEPTEAIGPDSPIEASAPTEASAPTEADAPAEPTDPTEADEPAGPDAPTEPEEPAEPAEPEAPVEPQPAVRLEGAGLRSGRGWVFRDVSFTAHTGTTTTLTGPSGSGRSTALLACAGRLDLTTGSAAVHPPRRRVRDHVNVARIAGVIGLDPQLSVADNVNDAADWARLRRTQARDLLATWRSRLDLQLPSRLPAGELAADELTLLHLLCATLGNPRAIVLDDFDANLTIPQIARLWKLTARVAAGRVSAPVAVIVSTVAALPPAGERVIHLGDANGAAA
>NZ_CP045920.1|WP_153878998.1|3485820_3486444_-|methyltransferase-domain-containing-protein
MVEKSRWETMVTENPDHSRWFVERFRAKAAAGEDVSGEARLVDALVPRAARILDAGCGSGRLAPHLLAQGHTVVGVDVDPVLIEAARADHPGGTWIVGDLAELDLPAAGVPAGFDAIVAAGNVMPFLAPSTRVGVLSRLRDHLAPGGRIATGFGAGRGYLIEDFLTDVGAAGLDVESRYESWDLRPFTPESGFLVAVLTRGRSGRPR
>NZ_CP045920.1|WP_153879007.1|3504048_3504654_+|TetR-family-transcriptional-regulator
MPKIIGSTLAEHRQQVRQKLFTALAELMGERGFDSVTLAQIAARAKVGRTSVYNHFPDKEALLLAFIEHETGEFVTNMRAALVGVEDPEEQLRVYVRAQLLLQHPYHFAPGPSLASVVSRDTVARLGEHVREVAQLLRSILSAGIEHGGLPEQDVSAVVPLIHSCLQSRTLPLNPVEREQAIETITAFVLRAVGAREVTAA
>NZ_CP045920.1|WP_153879008.1|3504711_3505518_+|dienelactone-hydrolase-family-protein
MSQPTSHVLPRPGGDLPVLRWHPAGLDTGPAAGVVLVQEIFGVTDYIRARAADLARAGYTVDVPVLFFRESSEPVPEDAPDLLERGLALAAATDWDTAVADTRATVARLTRDLAAAGPGSPPVTLLGFCYGGGLAYAAAAETAETPAPREPAAPDPRGPREPAEHTEPPASALVSYYGSALPALTAEPTLRVERPSLHHFGTADAYVPLEAVRAIRERVTAARAPVEFHLYDGAGHAFDNPIPRFHHARASAEAWRRTLVFLDRVRTA
>NZ_CP045920.1|WP_153879009.1|3505524_3506349_+|DUF2993-domain-containing-protein
MARTRARATRRRLLLPLVLVVLVVAVAVAGEAIARAQVHARVAGAIDSELPGSTGVSTSLPAHPILIDLVRGRLTDLEIHADRVPLESVLAEPLSVTAVDVRIGSASLTSPMTVHDVTASATVPMSDLSTLAAARLGHGGVLGDLRVSGGAGELTVSARVAGALPVEIALRPEARERELRLVPTRMTIAGADVGLTSPRLAEWGIDPAALDVRIGLDDAPPGIELRSAEVTPDGLRVTLTADRLVADGASGVGHGMTGTRTRSAPSASGYYAQS
>NZ_CP045920.1|WP_152909787.1|3506510_3508064_+|ATP-binding-cassette-domain-containing-protein
MTGTDTLLSLEGVSKGFPGVQALDNMRLDVRYGEVLALVGENGAGKSTLMKLLSGLYTPDSGTFTLDGEDYTPSGPRHAEELGISIIHQEFHLMPDLSVAQNIFIGREPRRAGLFTDDRRLNEMARELLDRLGLDLDPREPVHRLTVAKQQMVEIAKALSSSSTKVLIMDEPTAALNDAEVATLHELIRRFISPSTAVIYISHRMDELSAISDRITVIRDGLYVTTVETATTSMPEVIAHMVGREIDTSVGPQNVRADREVILAVEGLHTKELLQDVSFELRKGEILGFAGLMGAGRTEVARAIVGADPITDGTITLHGKPVRIPHPARAAEYGIGYLSEDRKRFGLMLNLAVSNNIALSSLSEHFSAAGFVRDRDINRVSRTHVDTLGVRTPSIKQVVGNLSGGNQQKVVIAKWLAKDCDVLIFDEPTRGIDVGAKDEIYRLLNELAAAGKSIIMISSELPEVLRMAHRVVVMSEGRVTGELESGDVTQENVMHLATLRPESESSRGSVTTEAGLA
>NZ_CP045920.1|WP_152909788.1|3508060_3509077_+|ABC-transporter-permease
MTTPTTTEVRSSTAGTGAGLMGHLRTGLQQMLAFAGLIVIMIVFSLASPVFFTFDNIVGNMLFSAVVIGTLALGTTFVIITAGIDLSIGTGMALCAVMAGNFITNIGLSWQLGVVLAIAFGGLVGLVNGVFIAVAKLPPFIATLAMMMVAEGLALVFSDSAPIYVDRDTDGGFMDLSTGTLIPQVPNAVLVLIGAAIIAGIVLNRTVLGRYTYAIGSNEEATAISGVNVTKWKILIYTFAGLFTGLAGVMIAARLGSAQPAIGMGYELQAIAAVVIGGTSLMGGKGSIVGTVIGALIISVINNGLQLMSVPQEWQNVILGAVILAAVFADTVRQRTTT
>NZ_CP045920.1|WP_153879010.1|3509194_3510196_+|substrate-binding-domain-containing-protein
MRRRTLLMGAAASAVTVGLAACSSGDDTGSADGGNNDGGEGGGDDLPYIAIVSKGFQHQFWQAVKNGAEDEAEGKATITFEGPATEADVEDQINMLQTALAKSPAAIGFAALDSKAAEGLLQQAQTQDIPVIAFDSGVDSDVPLTTASTDNKAAAAEAAKHMAELIGNKGKVAMVVHDQTSGSGQDRRDGFIEWMEANAPDVELMEPQYGDGDQNKSANITKSILTANPDVAGIYGSNEGSAIGVVKGVEEAGAGGDVVVVGFDSGKAQIDAIRSGLMAGAITQNPVGMGAEVVKAALKAIAGEELPETIDTGFYWYDASNIDDPEIAAVLYE
>NZ_CP045920.1|WP_153879011.1|3510361_3512314_+|potassium-transporter-Kup
MSEPPEVASQDRPDRARPTSAEDRATRAGGSRRVLFLLAVLGVVYGDLGTSTIYALRTAFSGRVVTLEATAANVLGILSLVLWTLILVVSIKYMGVILRLDNRGEGGLFALIALLRPWRALGRIRRRALVLLGLAGAAMLYAGVMITPAISILSAVEGLEIAAPGTGRLVVPITIAILVALFLVQRFGTARIGAAFGPVMALWFASIGALGLYGITRAPQVLAAIDPRRAAGFLAQAPVTGLVVLFAVFLVTTGAEALYADLGHFGTRSIRRLWFAFVLPALLLSYLGQGAGLLRDPSSSESPFFRLVPTALLVPMVVLATVATIIASQAAITGAFSLTRAAGRLGMMPPLRVVQTSAESPGQVYVPAINRILMSAAIVLVLTFQTSERLASAYGISVNTTMVVTTVLAFVITRERLGWPRWRAGVVFGAFLVAELAFLGSNLLRVPHGGWFPVLVGAGFFAVLSTWRRGGELLAGRTTADSHPIETVHTRLREEDVARVPGAAVFLTPWLTGTPPSLIHHVQRTRALQRRVVLLGVLVEDVPRTTADERIHVDDLGEGFARVVLHYGYLQRVNVPSELNRCRDRLGIDLDEVTYYIEHEQPLQGHGRRRGLAAWRERLYAVLKRNALDPTTRYQIPSDRIVDLGLRIRI
>NZ_CP045920.1|WP_153879317.1|3512478_3513984_-|hypothetical-protein
MRPVLSAGRAAGAVAGAAARAGSDRGERRRGGNDPAATERSGHDRGGRPRGGRESSTAGPDVTGAAARFSTIAAWCYVGVAVSGIANAVLRLGDLSGLGTTYGSLLIAKIVAFGLLGFAGAWHRRSTIAALAERPRAFWRLAGGELFVMAAAMGLAVVLASTAPPVPQDPIEAPSPAQVLSQRDVPLPPTFGRWFSEFYPDLLFGALTVVMAVVYIRWVLRLRRRGDSWPLGRTVPWLLGVLGFGYLNLGGAAVYGHILFSAHMIAHMSLVMILPILLVLGAPVTLAVRALPARRDGSRGPREWLLAIVHSRWAGFLSNPIVAAGNVIVSMAVFYFTPLIVFAMTTHIGHVLMIVHFTLIGYLFVNVLIGIDPGPTRPGYPLRLVLLLATMAFHAFFALAIMSMTDLIGADYFGRLGLPWGVDALADQYTGGQITWGIGELPSLALAVTLALMWAKTDERTARRTDRQADRDGGAELAEYNAMLARLADEEPEDSSHSPTR
>NZ_CP045920.1|WP_153879012.1|3514764_3515811_+|AAA-domain-containing-protein
MTPRRLPSMTTAAPSRLAPRTSPISFDEGQRATDLLGRMVRVFDQRIVGQEALRTALISSLVAGGHVLLESVPGLAKTTAAEILAASVGGKFHRIQCTPDLMPNDIVGTQIYNYGTGEFSTQLGPVHANLVLLDEINRSSAKTQAAMLEAMQERQTSIGGTNYPLPKPFMVMATQNPIEEEGTYVLPEAQMDRFLMKEVLSYPSPENEVTILDRIYTGSMEAPLTGSPITLADVSFLQHLTTKVYVDTAIKQYIVAIINTTRGGGPRPLPDFTKHVRVGSSPRGGIALMRIAQAVALQEGRSYVVPDDVKSFRHAILRHRLVRTYDALANNVAPEALIDAIFAAVPSP
>NZ_CP045920.1|WP_153879013.1|3515842_3516736_+|DUF58-domain-containing-protein
MTPNSPSRLAKVRARLDLPTVRRASGLLSGRHRSIYSGHGQDFDEMALYQYGDAISDIDWKASAASGIPVIRRFVRESNLAMVLALDTGRNMSATARDGDPKSAVALFAAELICYLARARGDTVALVAGDAERLIQLPARGGLSHMEMLLSRAEAMWTRQAPASDLVRVLDRTLAWFTRRSLVVVITDEARPTDEHEAALRRLRTRHEVMFVQVADALPTIDEHLAVDDVDHHLDIPQFLRASPGLAEQAAAYVAERRARTQALLRRRGIESVTATSIDDLINQLIDLLGRQKRVHH

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP045920_11	11.2\|3365873\|18\|NZ_CP045920\|PILER-CR	3365873-3365890	18	NZ_CP045920.1	3365922-3365939	0	1.0

1. spacer 11.2|3365873|18|NZ_CP045920|PILER-CR matches to position: 3365922-3365939, mismatch: 0, identity: 1.0

cagttcatcgtcgacggc	CRISPR spacer
cagttcatcgtcgacggc	Protospacer
******************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP045920_11	11.1\|3365801\|30\|NZ_CP045920\|PILER-CR	3365801-3365830	30	NZ_CP029051	Miniimonas sp. S16 plasmid pS16-2, complete sequence	15031-15060	1	0.967
NZ_CP045920_2	2.1\|545073\|25\|NZ_CP045920\|CRT	545073-545097	25	MN310371	Pseudomonas monteilii strain QJ20133 plasmid pJ20133-VIM, complete sequence	252466-252490	3	0.88
NZ_CP045920_2	2.3\|545187\|25\|NZ_CP045920\|CRT	545187-545211	25	MK737942	Microbacterium phage Sucha, complete genome	37548-37572	3	0.88
NZ_CP045920_2	2.3\|545187\|25\|NZ_CP045920\|CRT	545187-545211	25	NC_023283	Streptomyces sp. FR1 plasmid pFRL3, complete sequence	182043-182067	3	0.88
NZ_CP045920_2	2.3\|545187\|25\|NZ_CP045920\|CRT	545187-545211	25	NC_023284	Streptomyces sp. F2 plasmid pFRL4, complete sequence	218671-218695	3	0.88
NZ_CP045920_2	2.6\|545361\|25\|NZ_CP045920\|CRT	545361-545385	25	NZ_CP009292	Novosphingobium pentaromativorans US6-1 plasmid pLA3, complete sequence	270032-270056	3	0.88
NZ_CP045920_2	2.6\|545361\|25\|NZ_CP045920\|CRT	545361-545385	25	NZ_CP030864	Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence	140445-140469	3	0.88
NZ_CP045920_2	2.1\|545073\|25\|NZ_CP045920\|CRT	545073-545097	25	NZ_CP028898	Gammaproteobacteria bacterium DM2 plasmid unnamed, complete sequence	74681-74705	4	0.84
NZ_CP045920_2	2.1\|545073\|25\|NZ_CP045920\|CRT	545073-545097	25	NZ_CP045801	Pseudomonas syringae USA011 plasmid pUSA011-2, complete sequence	38234-38258	4	0.84
NZ_CP045920_2	2.1\|545073\|25\|NZ_CP045920\|CRT	545073-545097	25	NZ_KY362369	Pseudomonas syringae pv. syringae strain 6-9 plasmid pPs6-9, complete sequence	43978-44002	4	0.84
NZ_CP045920_2	2.1\|545073\|25\|NZ_CP045920\|CRT	545073-545097	25	NZ_KY362373	Pseudomonas syringae pv. syringae strain 7B44 plasmid pPs7B44, complete sequence	52515-52539	4	0.84
NZ_CP045920_2	2.1\|545073\|25\|NZ_CP045920\|CRT	545073-545097	25	NZ_KY362372	Pseudomonas syringae pv. syringae strain UMAF0170 plasmid pPs0170, complete sequence	47318-47342	4	0.84
NZ_CP045920_2	2.1\|545073\|25\|NZ_CP045920\|CRT	545073-545097	25	NZ_KY362368	Pseudomonas syringae pv. syringae strain UMAF0081 plasmid pPs0081, complete sequence	43978-44002	4	0.84
NZ_CP045920_2	2.1\|545073\|25\|NZ_CP045920\|CRT	545073-545097	25	NZ_CP024713	Pseudomonas syringae pv. actinidiae strain MAFF212063 plasmid pMAFF212063-A, complete sequence	50688-50712	4	0.84
NZ_CP045920_2	2.1\|545073\|25\|NZ_CP045920\|CRT	545073-545097	25	NZ_CP042805	Pseudomonas amygdali pv. tabaci str. ATCC 11528 plasmid pTab1, complete sequence	43979-44003	4	0.84
NZ_CP045920_2	2.1\|545073\|25\|NZ_CP045920\|CRT	545073-545097	25	NZ_CP007015	Pseudomonas syringae CC1557 plasmid pCC1557, complete sequence	13930-13954	4	0.84
NZ_CP045920_2	2.1\|545073\|25\|NZ_CP045920\|CRT	545073-545097	25	NZ_CP046036	Pseudomonas coronafaciens pv. oryzae str. 1_6 plasmid pPor1_6, complete sequence	34263-34287	4	0.84
NZ_CP045920_2	2.3\|545187\|25\|NZ_CP045920\|CRT	545187-545211	25	NZ_CP045548	Streptomyces sp. SYP-A7193 plasmid unnamed1, complete sequence	257022-257046	4	0.84
NZ_CP045920_2	2.3\|545187\|25\|NZ_CP045920\|CRT	545187-545211	25	NZ_CP045548	Streptomyces sp. SYP-A7193 plasmid unnamed1, complete sequence	257544-257568	4	0.84
NZ_CP045920_2	2.3\|545187\|25\|NZ_CP045920\|CRT	545187-545211	25	NZ_CP026539	Desulfovibrio carbinolicus strain DSM 3852 plasmid pDCAR1, complete sequence	101328-101352	4	0.84
NZ_CP045920_2	2.6\|545361\|25\|NZ_CP045920\|CRT	545361-545385	25	NZ_CP029834	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed4, complete sequence	156707-156731	4	0.84
NZ_CP045920_2	2.6\|545361\|25\|NZ_CP045920\|CRT	545361-545385	25	CP040467	Streptomyces albidoflavus strain UYFA156 plasmid unnamed, complete sequence	31340-31364	4	0.84
NZ_CP045920_2	2.6\|545361\|25\|NZ_CP045920\|CRT	545361-545385	25	NC_016624	Azospirillum lipoferum 4B plasmid AZO_p5, complete sequence	213631-213655	4	0.84
NZ_CP045920_2	2.3\|545187\|25\|NZ_CP045920\|CRT	545187-545211	25	NZ_CP022543	Antarctobacter heliothermus strain SMS3 plasmid pSMS3-3, complete sequence	73320-73344	5	0.8
NZ_CP045920_2	2.6\|545361\|25\|NZ_CP045920\|CRT	545361-545385	25	NZ_CP013110	Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence	134362-134386	5	0.8
NZ_CP045920_2	2.6\|545361\|25\|NZ_CP045920\|CRT	545361-545385	25	NZ_CP029452	Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence	69267-69291	5	0.8
NZ_CP045920_2	2.6\|545361\|25\|NZ_CP045920\|CRT	545361-545385	25	NZ_CP029452	Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence	533261-533285	5	0.8
NZ_CP045920_2	2.6\|545361\|25\|NZ_CP045920\|CRT	545361-545385	25	NZ_CP029452	Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence	638051-638075	5	0.8
NZ_CP045920_2	2.6\|545361\|25\|NZ_CP045920\|CRT	545361-545385	25	NZ_CP029452	Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence	1548500-1548524	5	0.8
NZ_CP045920_2	2.6\|545361\|25\|NZ_CP045920\|CRT	545361-545385	25	NZ_CP029452	Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence	1884885-1884909	5	0.8
NZ_CP045920_2	2.6\|545361\|25\|NZ_CP045920\|CRT	545361-545385	25	NZ_CP013579	Rhizobium phaseoli strain N671 plasmid pRphaN671e, complete sequence	941410-941434	5	0.8
NZ_CP045920_2	2.6\|545361\|25\|NZ_CP045920\|CRT	545361-545385	25	NZ_CP013573	Rhizobium phaseoli strain N771 plasmid pRphaN771e, complete sequence	941410-941434	5	0.8
NZ_CP045920_2	2.6\|545361\|25\|NZ_CP045920\|CRT	545361-545385	25	NZ_CP011665	Streptomyces sp. Mg1 plasmid pSMg1-1, complete sequence	12811-12835	5	0.8
NZ_CP045920_2	2.6\|545361\|25\|NZ_CP045920\|CRT	545361-545385	25	NZ_CP013054	Sinorhizobium americanum CCGM7 plasmid C, complete sequence	132410-132434	5	0.8
NZ_CP045920_2	2.6\|545361\|25\|NZ_CP045920\|CRT	545361-545385	25	NZ_CP038636	Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence	1003260-1003284	5	0.8
NZ_CP045920_2	2.6\|545361\|25\|NZ_CP045920\|CRT	545361-545385	25	NZ_CP029232	Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence	1675262-1675286	5	0.8
NZ_CP045920_2	2.6\|545361\|25\|NZ_CP045920\|CRT	545361-545385	25	NZ_CP029234	Sinorhizobium fredii CCBAU 45436 plasmid pSF45436d, complete sequence	56357-56381	5	0.8
NZ_CP045920_2	2.6\|545361\|25\|NZ_CP045920\|CRT	545361-545385	25	NZ_CP015372	Pandoraea pnomenusa strain MCB032 plasmid unnamed 1, complete sequence	40898-40922	5	0.8
NZ_CP045920_2	2.6\|545361\|25\|NZ_CP045920\|CRT	545361-545385	25	NZ_CP023069	Ensifer sojae CCBAU 05684 plasmid pSJ05684a, complete sequence	132116-132140	5	0.8
NZ_CP045920_2	2.6\|545361\|25\|NZ_CP045920\|CRT	545361-545385	25	NZ_CP023071	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence	1153418-1153442	5	0.8
NZ_CP045920_2	2.6\|545361\|25\|NZ_CP045920\|CRT	545361-545385	25	NZ_CP029233	Sinorhizobium fredii CCBAU 45436 plasmid pSF45436a, complete sequence	134368-134392	5	0.8
NZ_CP045920_2	2.6\|545361\|25\|NZ_CP045920\|CRT	545361-545385	25	NZ_CP024313	Rhizobium sp. NXC24 plasmid pRspNXC24b, complete sequence	216838-216862	6	0.76
NZ_CP045920_11	11.1\|3365801\|30\|NZ_CP045920\|PILER-CR	3365801-3365830	30	CP051275	Salmonella phage SW-37, complete genome	39760-39789	7	0.767
NZ_CP045920_11	11.1\|3365801\|30\|NZ_CP045920\|PILER-CR	3365801-3365830	30	NZ_CP015009	Aminobacter aminovorans strain KCTC 2477 plasmid pAA04, complete sequence	13893-13922	8	0.733
NZ_CP045920_11	11.1\|3365801\|30\|NZ_CP045920\|PILER-CR	3365801-3365830	30	NC_011370	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG203, complete sequence	175424-175453	8	0.733
NZ_CP045920_11	11.1\|3365801\|30\|NZ_CP045920\|PILER-CR	3365801-3365830	30	NC_011371	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG204, complete sequence	29884-29913	8	0.733
NZ_CP045920_11	11.1\|3365801\|30\|NZ_CP045920\|PILER-CR	3365801-3365830	30	NZ_CP049249	Rhizobium rhizoryzae strain DSM 29514 plasmid unnamed3, complete sequence	92466-92495	8	0.733
NZ_CP045920_11	11.1\|3365801\|30\|NZ_CP045920\|PILER-CR	3365801-3365830	30	NZ_CP049251	Rhizobium rhizoryzae strain DSM 29514 plasmid unnamed4, complete sequence	15182-15211	8	0.733
NZ_CP045920_11	11.1\|3365801\|30\|NZ_CP045920\|PILER-CR	3365801-3365830	30	NZ_CP050094	Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b4, complete sequence	206733-206762	8	0.733
NZ_CP045920_11	11.1\|3365801\|30\|NZ_CP045920\|PILER-CR	3365801-3365830	30	NC_008379	Rhizobium leguminosarum bv. viciae 3841 plasmid pRL9, complete sequence	190229-190258	8	0.733
NZ_CP045920_11	11.1\|3365801\|30\|NZ_CP045920\|PILER-CR	3365801-3365830	30	NZ_CP030762	Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed2, complete sequence	299262-299291	8	0.733
NZ_CP045920_11	11.1\|3365801\|30\|NZ_CP045920\|PILER-CR	3365801-3365830	30	NZ_CP013512	Rhizobium sp. N1314 plasmid pRspN1314a, complete sequence	79091-79120	8	0.733
NZ_CP045920_1	1.1\|492346\|34\|NZ_CP045920\|CRISPRCasFinder	492346-492379	34	NZ_CP034088	Methylocystis rosea strain GW6 plasmid pGW6_2, complete sequence	34021-34054	9	0.735
NZ_CP045920_11	11.1\|3365801\|30\|NZ_CP045920\|PILER-CR	3365801-3365830	30	NC_015952	Streptomyces violaceusniger Tu 4113 plasmid pSTRVI02, complete sequence	62049-62078	9	0.7
NZ_CP045920_11	11.1\|3365801\|30\|NZ_CP045920\|PILER-CR	3365801-3365830	30	NZ_CP050083	Rhizobium leguminosarum bv. trifolii strain 31B plasmid pRL31b3, complete sequence	396654-396683	9	0.7
NZ_CP045920_11	11.1\|3365801\|30\|NZ_CP045920\|PILER-CR	3365801-3365830	30	NZ_CP049733	Rhizobium leguminosarum strain A1 plasmid pRL10, complete sequence	384329-384358	9	0.7
NZ_CP045920_11	11.1\|3365801\|30\|NZ_CP045920\|PILER-CR	3365801-3365830	30	NZ_CP022365	Azospirillum sp. TSH58 plasmid TSH58_p06, complete sequence	52216-52245	9	0.7
NZ_CP045920_11	11.1\|3365801\|30\|NZ_CP045920\|PILER-CR	3365801-3365830	30	NZ_CP040763	Paracoccus sp. 2251 plasmid unnamed4, complete sequence	451-480	9	0.7
NZ_CP045920_11	11.1\|3365801\|30\|NZ_CP045920\|PILER-CR	3365801-3365830	30	NZ_CP053207	Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1C, complete sequence	413427-413456	9	0.7

1. spacer 11.1|3365801|30|NZ_CP045920|PILER-CR matches to NZ_CP029051 (Miniimonas sp. S16 plasmid pS16-2, complete sequence) position: , mismatch: 1, identity: 0.967

acacctgctgctcctggcgcccctcgaacg	CRISPR spacer
acacctgctgctcctggcgctcctcgaacg	Protospacer
********************.*********

2. spacer 2.1|545073|25|NZ_CP045920|CRT matches to MN310371 (Pseudomonas monteilii strain QJ20133 plasmid pJ20133-VIM, complete sequence) position: , mismatch: 3, identity: 0.88

tggctccgataccggggccggttcg	CRISPR spacer
tacctccgataccggggcgggttcg	Protospacer
*. *************** ******

3. spacer 2.3|545187|25|NZ_CP045920|CRT matches to MK737942 (Microbacterium phage Sucha, complete genome) position: , mismatch: 3, identity: 0.88

tgcccttgacggtggggccgatgtc	CRISPR spacer
tgcccttgccggtggagccgatgcc	Protospacer
******** ******.*******.*

4. spacer 2.3|545187|25|NZ_CP045920|CRT matches to NC_023283 (Streptomyces sp. FR1 plasmid pFRL3, complete sequence) position: , mismatch: 3, identity: 0.88

tgcccttgacggtggggccgatgtc	CRISPR spacer
tgccgttgacggtggcgccgatgac	Protospacer
**** ********** ******* *

5. spacer 2.3|545187|25|NZ_CP045920|CRT matches to NC_023284 (Streptomyces sp. F2 plasmid pFRL4, complete sequence) position: , mismatch: 3, identity: 0.88

tgcccttgacggtggggccgatgtc	CRISPR spacer
tgccgttgacggtggcgccgatgac	Protospacer
**** ********** ******* *

6. spacer 2.6|545361|25|NZ_CP045920|CRT matches to NZ_CP009292 (Novosphingobium pentaromativorans US6-1 plasmid pLA3, complete sequence) position: , mismatch: 3, identity: 0.88

agcgctcggcggcggagccgatgtc	CRISPR spacer
agcgttcggcggcggagccgatctt	Protospacer
****.***************** *.

7. spacer 2.6|545361|25|NZ_CP045920|CRT matches to NZ_CP030864 (Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence) position: , mismatch: 3, identity: 0.88

agcgctcggcggcggagccgatgtc	CRISPR spacer
cgcgctcggcggtggagccgatggc	Protospacer
 ***********.********** *

8. spacer 2.1|545073|25|NZ_CP045920|CRT matches to NZ_CP028898 (Gammaproteobacteria bacterium DM2 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.84

tggctccgataccggggccggttcg	CRISPR spacer
agcttcagataccggggccggttcg	Protospacer
 * .** ******************

9. spacer 2.1|545073|25|NZ_CP045920|CRT matches to NZ_CP045801 (Pseudomonas syringae USA011 plasmid pUSA011-2, complete sequence) position: , mismatch: 4, identity: 0.84

tggctccgataccggggccggttcg	CRISPR spacer
aggctcggagaccggggccggttcc	Protospacer
 ***** ** **************

10. spacer 2.1|545073|25|NZ_CP045920|CRT matches to NZ_KY362369 (Pseudomonas syringae pv. syringae strain 6-9 plasmid pPs6-9, complete sequence) position: , mismatch: 4, identity: 0.84

tggctccgataccggggccggttcg	CRISPR spacer
aggctcggagaccggggccggttct	Protospacer
 ***** ** **************

11. spacer 2.1|545073|25|NZ_CP045920|CRT matches to NZ_KY362373 (Pseudomonas syringae pv. syringae strain 7B44 plasmid pPs7B44, complete sequence) position: , mismatch: 4, identity: 0.84

tggctccgataccggggccggttcg	CRISPR spacer
aggctcggagaccggggccggttcc	Protospacer
 ***** ** **************

12. spacer 2.1|545073|25|NZ_CP045920|CRT matches to NZ_KY362372 (Pseudomonas syringae pv. syringae strain UMAF0170 plasmid pPs0170, complete sequence) position: , mismatch: 4, identity: 0.84

tggctccgataccggggccggttcg	CRISPR spacer
aggctcggagaccggggccggttct	Protospacer
 ***** ** **************

13. spacer 2.1|545073|25|NZ_CP045920|CRT matches to NZ_KY362368 (Pseudomonas syringae pv. syringae strain UMAF0081 plasmid pPs0081, complete sequence) position: , mismatch: 4, identity: 0.84

tggctccgataccggggccggttcg	CRISPR spacer
aggctcggagaccggggccggttct	Protospacer
 ***** ** **************

14. spacer 2.1|545073|25|NZ_CP045920|CRT matches to NZ_CP024713 (Pseudomonas syringae pv. actinidiae strain MAFF212063 plasmid pMAFF212063-A, complete sequence) position: , mismatch: 4, identity: 0.84

tggctccgataccggggccggttcg	CRISPR spacer
aggctcggagaccggggccggttct	Protospacer
 ***** ** **************

15. spacer 2.1|545073|25|NZ_CP045920|CRT matches to NZ_CP042805 (Pseudomonas amygdali pv. tabaci str. ATCC 11528 plasmid pTab1, complete sequence) position: , mismatch: 4, identity: 0.84

tggctccgataccggggccggttcg	CRISPR spacer
aggctcggagaccggggccggttct	Protospacer
 ***** ** **************

16. spacer 2.1|545073|25|NZ_CP045920|CRT matches to NZ_CP007015 (Pseudomonas syringae CC1557 plasmid pCC1557, complete sequence) position: , mismatch: 4, identity: 0.84

tggctccgataccggggccggttcg	CRISPR spacer
aggctcggagaccggggccggttcc	Protospacer
 ***** ** **************

17. spacer 2.1|545073|25|NZ_CP045920|CRT matches to NZ_CP046036 (Pseudomonas coronafaciens pv. oryzae str. 1_6 plasmid pPor1_6, complete sequence) position: , mismatch: 4, identity: 0.84

tggctccgataccggggccggttcg	CRISPR spacer
aggctcggagaccggggccggttcc	Protospacer
 ***** ** **************

18. spacer 2.3|545187|25|NZ_CP045920|CRT matches to NZ_CP045548 (Streptomyces sp. SYP-A7193 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.84

tgcccttgacggtggggccgatgtc	CRISPR spacer
ggcccttgacggtggggccggtggt	Protospacer
 *******************.** .

19. spacer 2.3|545187|25|NZ_CP045920|CRT matches to NZ_CP045548 (Streptomyces sp. SYP-A7193 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.84

tgcccttgacggtggggccgatgtc	CRISPR spacer
ggcccttgacggtggggccggtggt	Protospacer
 *******************.** .

20. spacer 2.3|545187|25|NZ_CP045920|CRT matches to NZ_CP026539 (Desulfovibrio carbinolicus strain DSM 3852 plasmid pDCAR1, complete sequence) position: , mismatch: 4, identity: 0.84

tgcccttgacggtggggccgatgtc	CRISPR spacer
tgcccttgacggtgtggcagatgag	Protospacer
************** *** ****

21. spacer 2.6|545361|25|NZ_CP045920|CRT matches to NZ_CP029834 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed4, complete sequence) position: , mismatch: 4, identity: 0.84

agcgctcggcggcggagccgatgtc	CRISPR spacer
tgcgctcggcggcggagcagatcgc	Protospacer
 ***************** ***  *

22. spacer 2.6|545361|25|NZ_CP045920|CRT matches to CP040467 (Streptomyces albidoflavus strain UYFA156 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.84

agcgctcggcggcggagccgatgtc	CRISPR spacer
cgcgctcggcggcggagccggcggc	Protospacer
 *******************..* *

23. spacer 2.6|545361|25|NZ_CP045920|CRT matches to NC_016624 (Azospirillum lipoferum 4B plasmid AZO_p5, complete sequence) position: , mismatch: 4, identity: 0.84

agcgctcggcggcggagccgatgtc	CRISPR spacer
tgcgctcggcggcggagcagatcgc	Protospacer
 ***************** ***  *

24. spacer 2.3|545187|25|NZ_CP045920|CRT matches to NZ_CP022543 (Antarctobacter heliothermus strain SMS3 plasmid pSMS3-3, complete sequence) position: , mismatch: 5, identity: 0.8

tgcccttgacggtggggccgatgtc	CRISPR spacer
ttcccttgacggtggggccgacaat	Protospacer
* *******************.. .

25. spacer 2.6|545361|25|NZ_CP045920|CRT matches to NZ_CP013110 (Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence) position: , mismatch: 5, identity: 0.8

agcgctcggcggcggagccgatgtc	CRISPR spacer
ggcgctcggcggcgaagccgattat	Protospacer
.*************.*******  .

26. spacer 2.6|545361|25|NZ_CP045920|CRT matches to NZ_CP029452 (Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence) position: , mismatch: 5, identity: 0.8

agcgctcggcggcggagccgatgtc	CRISPR spacer
ggcgctcggcggcgaagccgatcat	Protospacer
.*************.*******  .

27. spacer 2.6|545361|25|NZ_CP045920|CRT matches to NZ_CP029452 (Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence) position: , mismatch: 5, identity: 0.8

agcgctcggcggcggagccgatgtc	CRISPR spacer
ggcgctcggcggcgaagccgatcat	Protospacer
.*************.*******  .

28. spacer 2.6|545361|25|NZ_CP045920|CRT matches to NZ_CP029452 (Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence) position: , mismatch: 5, identity: 0.8

agcgctcggcggcggagccgatgtc	CRISPR spacer
ggcgctcggcggcgaagccgatcat	Protospacer
.*************.*******  .

29. spacer 2.6|545361|25|NZ_CP045920|CRT matches to NZ_CP029452 (Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence) position: , mismatch: 5, identity: 0.8

agcgctcggcggcggagccgatgtc	CRISPR spacer
ggcgctcggcggcgaagccgatcat	Protospacer
.*************.*******  .

30. spacer 2.6|545361|25|NZ_CP045920|CRT matches to NZ_CP029452 (Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence) position: , mismatch: 5, identity: 0.8

agcgctcggcggcggagccgatgtc	CRISPR spacer
ggcgctcggcggcgaagccgatcat	Protospacer
.*************.*******  .

31. spacer 2.6|545361|25|NZ_CP045920|CRT matches to NZ_CP013579 (Rhizobium phaseoli strain N671 plasmid pRphaN671e, complete sequence) position: , mismatch: 5, identity: 0.8

agcgctcggcggcggagccgatgtc	CRISPR spacer
ggtcggcggcggcggagccgatgtc	Protospacer
.*.   *******************

32. spacer 2.6|545361|25|NZ_CP045920|CRT matches to NZ_CP013573 (Rhizobium phaseoli strain N771 plasmid pRphaN771e, complete sequence) position: , mismatch: 5, identity: 0.8

agcgctcggcggcggagccgatgtc	CRISPR spacer
ggtcggcggcggcggagccgatgtc	Protospacer
.*.   *******************

33. spacer 2.6|545361|25|NZ_CP045920|CRT matches to NZ_CP011665 (Streptomyces sp. Mg1 plasmid pSMg1-1, complete sequence) position: , mismatch: 5, identity: 0.8

agcgctcggcggcggagccgatgtc	CRISPR spacer
ggcgctcggcggcggagccgccgcg	Protospacer
.******************* .*.

34. spacer 2.6|545361|25|NZ_CP045920|CRT matches to NZ_CP013054 (Sinorhizobium americanum CCGM7 plasmid C, complete sequence) position: , mismatch: 5, identity: 0.8

agcgctcggcggcggagccgatgtc	CRISPR spacer
ggcgctcggcggcgaagccgattat	Protospacer
.*************.*******  .

35. spacer 2.6|545361|25|NZ_CP045920|CRT matches to NZ_CP038636 (Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.8

agcgctcggcggcggagccgatgtc	CRISPR spacer
agagctcggcggcggagccgagcag	Protospacer
** ******************

36. spacer 2.6|545361|25|NZ_CP045920|CRT matches to NZ_CP029232 (Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence) position: , mismatch: 5, identity: 0.8

agcgctcggcggcggagccgatgtc	CRISPR spacer
ggcgctcggcggcgaagccgatcat	Protospacer
.*************.*******  .

37. spacer 2.6|545361|25|NZ_CP045920|CRT matches to NZ_CP029234 (Sinorhizobium fredii CCBAU 45436 plasmid pSF45436d, complete sequence) position: , mismatch: 5, identity: 0.8

agcgctcggcggcggagccgatgtc	CRISPR spacer
ggcgctcggcggcgaagccgatcat	Protospacer
.*************.*******  .

38. spacer 2.6|545361|25|NZ_CP045920|CRT matches to NZ_CP015372 (Pandoraea pnomenusa strain MCB032 plasmid unnamed 1, complete sequence) position: , mismatch: 5, identity: 0.8

agcgctcggcggcggagccgatgtc	CRISPR spacer
gccgatcggcggcggagccgatgcg	Protospacer
. ** ******************.

39. spacer 2.6|545361|25|NZ_CP045920|CRT matches to NZ_CP023069 (Ensifer sojae CCBAU 05684 plasmid pSJ05684a, complete sequence) position: , mismatch: 5, identity: 0.8

agcgctcggcggcggagccgatgtc	CRISPR spacer
ggcgctcggcggcgaagccgatcat	Protospacer
.*************.*******  .

40. spacer 2.6|545361|25|NZ_CP045920|CRT matches to NZ_CP023071 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence) position: , mismatch: 5, identity: 0.8

agcgctcggcggcggagccgatgtc	CRISPR spacer
ggcgctcggcggcgaagccgatcat	Protospacer
.*************.*******  .

41. spacer 2.6|545361|25|NZ_CP045920|CRT matches to NZ_CP029233 (Sinorhizobium fredii CCBAU 45436 plasmid pSF45436a, complete sequence) position: , mismatch: 5, identity: 0.8

agcgctcggcggcggagccgatgtc	CRISPR spacer
ggcgctcggcggcgaagccgatcat	Protospacer
.*************.*******  .

42. spacer 2.6|545361|25|NZ_CP045920|CRT matches to NZ_CP024313 (Rhizobium sp. NXC24 plasmid pRspNXC24b, complete sequence) position: , mismatch: 6, identity: 0.76

agcgctcggcggcggagccgatgtc	CRISPR spacer
gacgctcggcggcggagccgagcgt	Protospacer
..*******************   .

43. spacer 11.1|3365801|30|NZ_CP045920|PILER-CR matches to CP051275 (Salmonella phage SW-37, complete genome) position: , mismatch: 7, identity: 0.767

acacctgctgctcctggcgcccctcgaacg	CRISPR spacer
ccgtcgcctgctcctggcgcacatcgaacg	Protospacer
 *..*  ************* * *******

44. spacer 11.1|3365801|30|NZ_CP045920|PILER-CR matches to NZ_CP015009 (Aminobacter aminovorans strain KCTC 2477 plasmid pAA04, complete sequence) position: , mismatch: 8, identity: 0.733

acacctgctgctcctggcgcccctcgaacg	CRISPR spacer
tgtcctgctgctcctggcgctccttgataa	Protospacer
   *****************.***.**  .

45. spacer 11.1|3365801|30|NZ_CP045920|PILER-CR matches to NC_011370 (Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG203, complete sequence) position: , mismatch: 8, identity: 0.733

acacctgctgctcctggcgcccctcgaacg	CRISPR spacer
ttgcctgctgctcctggcgcgccttgatat	Protospacer
 ..***************** ***.**

46. spacer 11.1|3365801|30|NZ_CP045920|PILER-CR matches to NC_011371 (Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG204, complete sequence) position: , mismatch: 8, identity: 0.733

acacctgctgctcctggcgcccctcgaacg	CRISPR spacer
ttgcctgctgctcctggcgcgccttgatat	Protospacer
 ..***************** ***.**

47. spacer 11.1|3365801|30|NZ_CP045920|PILER-CR matches to NZ_CP049249 (Rhizobium rhizoryzae strain DSM 29514 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.733

acacctgctgctcctggcgcccctcgaacg	CRISPR spacer
tgtcctgctgctcctggcgctccttgatat	Protospacer
   *****************.***.**

48. spacer 11.1|3365801|30|NZ_CP045920|PILER-CR matches to NZ_CP049251 (Rhizobium rhizoryzae strain DSM 29514 plasmid unnamed4, complete sequence) position: , mismatch: 8, identity: 0.733

acacctgctgctcctggcgcccctcgaacg	CRISPR spacer
tgtcctgctgctcctggcgctccttgatat	Protospacer
   *****************.***.**

49. spacer 11.1|3365801|30|NZ_CP045920|PILER-CR matches to NZ_CP050094 (Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b4, complete sequence) position: , mismatch: 8, identity: 0.733

acacctgctgctcctggcgcccctcgaacg	CRISPR spacer
gcgactgctgctcctggcgctccttgatat	Protospacer
.*. ****************.***.**

50. spacer 11.1|3365801|30|NZ_CP045920|PILER-CR matches to NC_008379 (Rhizobium leguminosarum bv. viciae 3841 plasmid pRL9, complete sequence) position: , mismatch: 8, identity: 0.733

acacctgctgctcctggcgcccctcgaacg	CRISPR spacer
gcgactgctgctcctggcgctccttgatat	Protospacer
.*. ****************.***.**

51. spacer 11.1|3365801|30|NZ_CP045920|PILER-CR matches to NZ_CP030762 (Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

acacctgctgctcctggcgcccctcgaacg	CRISPR spacer
gcgactgctgctcctggcgctccttgatat	Protospacer
.*. ****************.***.**

52. spacer 11.1|3365801|30|NZ_CP045920|PILER-CR matches to NZ_CP013512 (Rhizobium sp. N1314 plasmid pRspN1314a, complete sequence) position: , mismatch: 8, identity: 0.733

acacctgctgctcctggcgcccctcgaacg	CRISPR spacer
tcggctgctgctcctggcgctccttgatat	Protospacer
 *. ****************.***.**

53. spacer 1.1|492346|34|NZ_CP045920|CRISPRCasFinder matches to NZ_CP034088 (Methylocystis rosea strain GW6 plasmid pGW6_2, complete sequence) position: , mismatch: 9, identity: 0.735

gctgtcggaggcgccgccgatttcggaggttcct	CRISPR spacer
gttgtcgaaagcgccgccgatttcggggacgacc	Protospacer
*.*****.*.****************.*..  *.

54. spacer 11.1|3365801|30|NZ_CP045920|PILER-CR matches to NC_015952 (Streptomyces violaceusniger Tu 4113 plasmid pSTRVI02, complete sequence) position: , mismatch: 9, identity: 0.7

acacctgctgctcctggcgcccctcgaacg	CRISPR spacer
cgccctgctgctcctggtgctcctcggcac	Protospacer
   **************.**.*****.

55. spacer 11.1|3365801|30|NZ_CP045920|PILER-CR matches to NZ_CP050083 (Rhizobium leguminosarum bv. trifolii strain 31B plasmid pRL31b3, complete sequence) position: , mismatch: 9, identity: 0.7

acacctgctgctcctggcgcccctcgaacg	CRISPR spacer
ttgtctgctgctcctggcgctccttgatat	Protospacer
 ...****************.***.**

56. spacer 11.1|3365801|30|NZ_CP045920|PILER-CR matches to NZ_CP049733 (Rhizobium leguminosarum strain A1 plasmid pRL10, complete sequence) position: , mismatch: 9, identity: 0.7

acacctgctgctcctggcgcccctcgaacg	CRISPR spacer
ttgtctgctgctcctggcgctccttgatat	Protospacer
 ...****************.***.**

57. spacer 11.1|3365801|30|NZ_CP045920|PILER-CR matches to NZ_CP022365 (Azospirillum sp. TSH58 plasmid TSH58_p06, complete sequence) position: , mismatch: 9, identity: 0.7

acacctgctgctcctggcgcccctcgaacg	CRISPR spacer
catcctgctcctcctggcgctcctcggcgt	Protospacer
   ****** **********.*****.

58. spacer 11.1|3365801|30|NZ_CP045920|PILER-CR matches to NZ_CP040763 (Paracoccus sp. 2251 plasmid unnamed4, complete sequence) position: , mismatch: 9, identity: 0.7

acacctgctgctcctggcgcccctcgaacg	CRISPR spacer
ctgcctgctgctgctggcgtccctcgcgtc	Protospacer
 ..********* ******.****** ..

59. spacer 11.1|3365801|30|NZ_CP045920|PILER-CR matches to NZ_CP053207 (Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1C, complete sequence) position: , mismatch: 9, identity: 0.7

acacctgctgctcctggcgcccctcgaacg	CRISPR spacer
ttgtctgctgctcctggcgctccttgatat	Protospacer
 ...****************.***.**

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

650953 : 713933

Mycobacterium_phage(14.29%)

plate,integrase,tail,transposase

attL 645503:645520|attR 671916:671933

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
645503:645520	attL	NA	NA	NA	NA
WP_153877311.1\|650953_652306_+\|integrase	tyrosine-type recombinase/integrase	A0A1J0MDL3	Mycobacterium_phage	5.7e-73	42.0
WP_153877312.1\|652775_653387_+	hypothetical protein	NA	NA	NA	NA
WP_153877313.1\|653355_654504_+	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_153877314.1\|654623_654791_-	hypothetical protein	NA	NA	NA	NA
WP_153879134.1\|655182_655407_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_153877315.1\|655369_656083_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_153877316.1\|656081_656423_+	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_153877317.1\|656712_657441_+	hypothetical protein	NA	NA	NA	NA
WP_153877318.1\|657437_657734_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_153877319.1\|657730_658624_+	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	6.5e-17	28.5
WP_152817403.1\|658620_659439_+	ABC transporter permease	NA	NA	NA	NA
WP_152817404.1\|659463_659943_+	hypothetical protein	NA	NA	NA	NA
WP_153879135.1\|660067_660841_+	N-dimethylarginine dimethylaminohydrolase	NA	NA	NA	NA
WP_153877320.1\|660837_662010_+	ornithine--oxo-acid transaminase	NA	NA	NA	NA
WP_153877321.1\|662176_667246_+	hypothetical protein	NA	NA	NA	NA
WP_153877322.1\|667363_667756_-	large conductance mechanosensitive channel protein MscL	NA	NA	NA	NA
WP_153877323.1\|667811_668447_-	hypothetical protein	NA	NA	NA	NA
WP_153877324.1\|668587_668953_-	FmdB family transcriptional regulator	NA	NA	NA	NA
WP_153879136.1\|669015_671679_+	penicillin acylase family protein	NA	NA	NA	NA
WP_153879137.1\|671702_672296_-	5-formyltetrahydrofolate cyclo-ligase	NA	NA	NA	NA
671916:671933	attR	NA	NA	NA	NA
WP_153877325.1\|672448_673351_+	UTP--glucose-1-phosphate uridylyltransferase	A0A127AW70	Bacillus_phage	5.3e-67	46.1
WP_153877326.1\|673389_674604_+	molybdopterin molybdenumtransferase MoeA	NA	NA	NA	NA
WP_153877327.1\|674611_675193_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_153877328.1\|675280_676243_+	hypothetical protein	NA	NA	NA	NA
WP_153879138.1\|676836_677202_-	hypothetical protein	NA	NA	NA	NA
WP_153879139.1\|677237_677507_-	hypothetical protein	NA	NA	NA	NA
WP_153877329.1\|677639_678050_+	HTH domain-containing protein	NA	NA	NA	NA
WP_152817412.1\|679323_679587_+	hypothetical protein	NA	NA	NA	NA
WP_153877330.1\|679726_680974_-\|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	2.8e-74	42.9
WP_152817414.1\|681372_681675_+	metal-sensing transcriptional repressor	NA	NA	NA	NA
WP_153877331.1\|681731_681947_+	copper ion binding protein	NA	NA	NA	NA
WP_153877332.1\|684524_685598_-	winged helix DNA-binding domain-containing protein	NA	NA	NA	NA
WP_153877333.1\|685731_686715_+	ATP-binding cassette domain-containing protein	W6JKT0	Anomala_cuprea_entomopoxvirus	1.6e-13	28.4
WP_152817419.1\|686711_687455_+	ABC transporter permease	NA	NA	NA	NA
WP_153877334.1\|687491_688646_+	two-component sensor histidine kinase	NA	NA	NA	NA
WP_153877335.1\|688642_689263_+	response regulator	NA	NA	NA	NA
WP_152817421.1\|689295_689856_-	type II toxin-antitoxin system PemK/MazF family toxin	NA	NA	NA	NA
WP_153877336.1\|689910_690927_-	zinc-binding dehydrogenase	A0A1E1EWH3	Acanthamoeba_castellanii_mimivirus	1.3e-05	27.6
WP_153877337.1\|691007_693344_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_153877338.1\|693340_693859_-	hypothetical protein	NA	NA	NA	NA
WP_153877339.1\|693855_694668_-	hypothetical protein	NA	NA	NA	NA
WP_153877340.1\|694725_695118_-	L-ectoine synthase	NA	NA	NA	NA
WP_153877341.1\|695134_696403_-	diaminobutyrate--2-oxoglutarate transaminase	NA	NA	NA	NA
WP_153877342.1\|696492_697014_-	diaminobutyrate acetyltransferase	NA	NA	NA	NA
WP_153877343.1\|697254_698103_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_152817428.1\|698099_698747_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_152817429.1\|698768_699680_-	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_153877344.1\|699633_700812_+	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_153877345.1\|700808_703034_+	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_153877346.1\|703111_706255_+	hypothetical protein	NA	NA	NA	NA
WP_153877347.1\|706241_707474_-	zinc ribbon domain-containing protein	NA	NA	NA	NA
WP_153877348.1\|708007_708547_-\|tail	phage tail protein	NA	NA	NA	NA
WP_153877349.1\|708546_710502_-\|plate	putative baseplate assembly protein	A0A1J0GW37	Streptomyces_phage	2.8e-12	24.7
WP_152817436.1\|710501_710906_-\|plate	baseplate protein	NA	NA	NA	NA
WP_153877350.1\|710916_712728_-	VgrG-related protein	NA	NA	NA	NA
WP_152817438.1\|712702_713488_-	peptidase M23	NA	NA	NA	NA
WP_153877351.1\|713507_713933_-\|tail	phage tail protein	NA	NA	NA	NA

DBSCAN-SWA_2

2999354 : 3076203

Prochlorococcus_phage(12.5%)

tRNA,transposase,integrase

attL 2995286:2995309|attR 3083252:3083275

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2995286:2995309	attL	NA	NA	NA	NA
WP_153879153.1\|2999354_3000902_-\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_153879285.1\|3002685_3004134_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_153878710.1\|3004182_3005478_-	DUF559 domain-containing protein	NA	NA	NA	NA
WP_153878711.1\|3005511_3008577_-	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_153878712.1\|3008747_3009731_-	malate dehydrogenase	NA	NA	NA	NA
WP_153878713.1\|3009885_3012117_+	NADP-dependent isocitrate dehydrogenase	NA	NA	NA	NA
WP_153878714.1\|3012192_3012468_-	DUF3017 domain-containing protein	NA	NA	NA	NA
WP_153878715.1\|3012753_3013464_+	hypothetical protein	NA	NA	NA	NA
WP_153878716.1\|3013473_3014742_+	pyridine nucleotide-disulfide oxidoreductase	NA	NA	NA	NA
WP_153878717.1\|3014808_3016446_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	1.3e-58	45.0
WP_153878718.1\|3016539_3017676_-	hypothetical protein	NA	NA	NA	NA
WP_153878719.1\|3017816_3021158_+	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_153878720.1\|3021246_3021876_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.5e-12	28.6
WP_152910011.1\|3021995_3022568_+	hypothetical protein	NA	NA	NA	NA
WP_153878721.1\|3022639_3023896_-	hypothetical protein	NA	NA	NA	NA
WP_152910009.1\|3023971_3024862_-	succinate--CoA ligase subunit alpha	NA	NA	NA	NA
WP_153878722.1\|3024891_3026067_-	ADP-forming succinate--CoA ligase subunit beta	NA	NA	NA	NA
WP_153878723.1\|3026207_3028070_-	hypothetical protein	NA	NA	NA	NA
WP_153878724.1\|3027762_3029790_-	acyltransferase family protein	A0A166XZF2	Gordonia_phage	6.0e-26	27.4
WP_153879286.1\|3029895_3030597_-	WYL domain-containing protein	NA	NA	NA	NA
WP_152910005.1\|3030670_3031411_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_152910004.1\|3031465_3033889_-	DNA helicase PcrA	A7KV33	Bacillus_phage	3.7e-123	38.3
WP_153878725.1\|3034165_3034504_-	hypothetical protein	NA	NA	NA	NA
WP_153878726.1\|3034576_3035248_-	response regulator	NA	NA	NA	NA
WP_153879287.1\|3035244_3036501_-	PspC domain-containing protein	NA	NA	NA	NA
WP_153878727.1\|3038391_3038979_+	hypothetical protein	NA	NA	NA	NA
WP_153878728.1\|3039187_3042334_+	hypothetical protein	NA	NA	NA	NA
WP_153878729.1\|3042370_3043153_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_153878730.1\|3043241_3044801_-	glutamine-hydrolyzing GMP synthase	NA	NA	NA	NA
WP_152909997.1\|3044832_3045231_-	DUF3817 domain-containing protein	NA	NA	NA	NA
WP_153879288.1\|3045241_3046072_-	SURF1 family protein	NA	NA	NA	NA
WP_153878731.1\|3046288_3048391_+	phosphate acetyltransferase	NA	NA	NA	NA
WP_153878732.1\|3048387_3049626_+	acetate/propionate family kinase	NA	NA	NA	NA
WP_152909994.1\|3049867_3050386_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_153878733.1\|3050389_3051793_-	aspartate ammonia-lyase	NA	NA	NA	NA
WP_153878734.1\|3052018_3052948_+	hypothetical protein	NA	NA	NA	NA
WP_153878735.1\|3053036_3056099_-\|tRNA	glycine--tRNA ligase	NA	NA	NA	NA
WP_153878736.1\|3056168_3057245_-	pyridoxal-phosphate dependent enzyme	NA	NA	NA	NA
WP_153878737.1\|3057248_3058373_-	GuaB3 family IMP dehydrogenase-related protein	NA	NA	NA	NA
WP_152910025.1\|3058539_3060048_-	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	5.0e-86	37.5
WP_153878738.1\|3060168_3060849_+	hypothetical protein	NA	NA	NA	NA
WP_153878739.1\|3060916_3061213_-	co-chaperone GroES	A0A221S4M3	uncultured_virus	1.5e-18	49.5
WP_152909986.1\|3061440_3062097_+	thioredoxin domain-containing protein	NA	NA	NA	NA
WP_153878740.1\|3062093_3062255_+	hypothetical protein	NA	NA	NA	NA
WP_153878741.1\|3062259_3063465_+	SAM-dependent methyltransferase	NA	NA	NA	NA
WP_153878742.1\|3063499_3063769_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_152909984.1\|3063775_3064054_-	type II toxin-antitoxin system prevent-host-death family antitoxin	NA	NA	NA	NA
WP_153878743.1\|3064106_3064589_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_153878744.1\|3064660_3065806_+	glutamate--cysteine ligase	NA	NA	NA	NA
WP_153878745.1\|3065869_3066361_-	hypothetical protein	NA	NA	NA	NA
WP_153878746.1\|3066468_3066828_-	hypothetical protein	NA	NA	NA	NA
WP_153878747.1\|3067187_3067616_+	hypothetical protein	NA	NA	NA	NA
WP_153878748.1\|3067622_3068369_-	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	6.6e-07	23.8
WP_153878749.1\|3068368_3069163_-	ABC transporter permease	NA	NA	NA	NA
WP_153878750.1\|3069412_3070084_+	hypothetical protein	NA	NA	NA	NA
WP_153878273.1\|3071183_3072410_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_153878272.1\|3072406_3073363_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_153878271.1\|3073359_3074346_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_153878751.1\|3074955_3076203_+\|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	2.8e-74	42.9
3083252:3083275	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP045920

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection