CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP045571	Acidithiobacillus thiooxidans ATCC 19377 chromosome, complete genome	4 crisprs	TnsE_C,csa3,Cas9_archaeal,DEDDh,RT,cas14j,TnpB_regular.1,c2c8_V-U2,c2c9_V-U4,cas3,DinG	0	0	13	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP045571_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045571_1

106850-106992

Orphan

Consensus_repeat	Method
AAAAGTTACCAACTTTATTTGT	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP045571_1

>merge|NZ_CP045571|1|106850-106992|PILER-CR
GATTGTTACCAACTTTATTTGCACAAAATTTAGGGGCTTTGATCTTGAGCGGATGAAAAGTTACCAACTTTATTTATTTTTGAAAATCTCGATGCGCCAATTTTAGGGGCCCAGGACTTGAAAAAGTTACCAACTTTATTTGT

>NZ_CP045571|1|1|106850-106992|PILER-CR
GATTGTTACCAACTTTATTTGC	ACAAAATTTAGGGGCTTTGATCTTGAGCGGATG
AAAAGTTACCAACTTTATTTAT	TTTTGAAAATCTCGATGCGCCAATTTTAGGGGCCCAGGACTTGA
AAAAGTTACCAACTTTATTTGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045571.1\|WP_153940354.1\|98643_100023_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|379862
NZ_CP045571.1\|WP_010640796.1\|107718_108006_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|338835
NZ_CP045571.1\|WP_024894521.1\|113895_116622_+\|DNA-polymerase-I	unknown	unknown	gnl\|CDD\|235591
NZ_CP045571.1\|WP_101536851.1\|103163_103706_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045571.1\|WP_153940349.1\|93075_93321_-\|NrdH-redoxin	unknown	unknown	gnl\|CDD\|239274
NZ_CP045571.1\|WP_153940348.1\|92747_92912_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045571.1\|WP_153940356.1\|104273_106223_-\|diguanylate-cyclase	unknown	unknown	gnl\|CDD\|236645
NZ_CP045571.1\|WP_024894520.1\|113106_113826_-\|TIGR00730-family-Rossman-fold-protein	unknown	unknown	gnl\|CDD\|224527
NZ_CP045571.1\|WP_031575890.1\|109100_111230_+\|UvrD-helicase-domain-containing-protein	unknown	unknown	gnl\|CDD\|236976
NZ_CP045571.1\|WP_153940353.1\|97369_98647_+\|TolC-family-protein	unknown	unknown	gnl\|CDD\|224455
NZ_CP045571.1\|WP_153940351.1\|94029_96540_-\|heavy-metal-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319783
NZ_CP045571.1\|WP_024894517.1\|111309_111750_+\|ComEA-family-DNA-binding-protein	unknown	unknown	gnl\|CDD\|378965
NZ_CP045571.1\|WP_153940350.1\|93342_93549_-\|cation-transporter	unknown	unknown	gnl\|CDD\|184298
NZ_CP045571.1\|WP_153940355.1\|100015_103126_+\|CusA/CzcA-family-heavy-metal-efflux-RND-transporter	unknown	unknown	gnl\|CDD\|226220
NZ_CP045571.1\|WP_024894519.1\|112726_113089_-\|DUF2782-domain-containing-protein	unknown	unknown	gnl\|CDD\|378588
NZ_CP045571.1\|WP_024894518.1\|111766_112699_-\|homoserine-kinase	unknown	unknown	gnl\|CDD\|235369
NZ_CP045571.1\|WP_024894515.1\|108021_108984_-\|DnaJ-domain-containing-protein	unknown	unknown	gnl\|CDD\|182347
NZ_CP045571.1\|WP_170286679.1\|96861_97131_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045571.1\|WP_010640780.1\|116618_117881_-\|voltage-gated-potassium-channel-protein	unknown	unknown	gnl\|CDD\|236711
NZ_CP045571.1\|WP_024894514.1\|107165_107696_-\|methylated-DNA--[protein]-cysteine-S-methyltransferase	unknown	unknown	gnl\|CDD\|223427

Protein	Function_ID	Function_description	E-value
NZ_CP045571.1\|WP_153940354.1\|98643_100023_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|379862	pfam16576, HlyD_D23, Barrel-sandwich domain of CusB or HlyD membrane-fusion. HlyD_D23 is the combined domains 2 and 3 of the membrane-fusion proteins CusB and HlyD, which forms a barrel-sandwich. CusB and HlyD proteins are membrane fusion proteins of the CusCFBA copper efflux system in E.coli and related bacteria. The whole molecule hinges between D2 and D3. Efflux systems of this resistance-nodulation-division group - RND - have been developed to excrete poisonous metal ions, and in E.coli the only one that deals with silver and copper is the CusA transporter. The transporter CusA works in conjunction with a periplasmic component that is a membrane fusion protein, eg CusB, and an outer-membrane channel component CusC in a CusABC complex driven by import of protons.	1.02648e-93
NZ_CP045571.1\|WP_010640796.1\|107718_108006_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|338835	pfam13591, MerR_2, MerR HTH family regulatory protein.	2.26571e-14
NZ_CP045571.1\|WP_024894521.1\|113895_116622_+\|DNA-polymerase-I	gnl\|CDD\|235591	PRK05755, PRK05755, DNA polymerase I; Provisional.	0
NZ_CP045571.1\|WP_153940349.1\|93075_93321_-\|NrdH-redoxin	gnl\|CDD\|239274	cd02976, NrdH, NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase activity that is dependent on TRX reductase, not glutathione (GSH). It is part of the NrdHIEF operon, where NrdEF codes for class Ib ribonucleotide reductase (RNR-Ib), an efficient enzyme at low oxygen levels. Under these conditions when GSH is mostly conjugated to spermidine, NrdH can still function and act as a hydrogen donor for RNR-Ib. It has been suggested that the NrdHEF system may be the oldest RNR reducing system, capable of functioning in a microaerophilic environment, where GSH was not yet available. NrdH from Corynebacterium ammoniagenes can form domain-swapped dimers, although it is unknown if this happens in vivo. Domain-swapped dimerization, which results in the blocking of the TRX reductase binding site, could be a mechanism for regulating the oxidation state of the protein.	7.70319e-15
NZ_CP045571.1\|WP_031575890.1\|109100_111230_+\|UvrD-helicase-domain-containing-protein	gnl\|CDD\|236976	PRK11773, uvrD, DNA-dependent helicase II; Provisional.	0
NZ_CP045571.1\|WP_024894520.1\|113106_113826_-\|TIGR00730-family-Rossman-fold-protein	gnl\|CDD\|224527	COG1611, COG1611, Predicted Rossmann fold nucleotide-binding protein [General function prediction only].	1.00157e-52
NZ_CP045571.1\|WP_153940356.1\|104273_106223_-\|diguanylate-cyclase	gnl\|CDD\|236645	PRK10060, PRK10060, cyclic di-GMP phosphodiesterase.	1.10041e-63
NZ_CP045571.1\|WP_153940353.1\|97369_98647_+\|TolC-family-protein	gnl\|CDD\|224455	COG1538, TolC, Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion].	5.43856e-24
NZ_CP045571.1\|WP_153940351.1\|94029_96540_-\|heavy-metal-translocating-P-type-ATPase	gnl\|CDD\|319783	cd02094, P-type_ATPase_Cu-like, P-type heavy metal-transporting ATPase, similar to human copper-transporting ATPases, ATP7A and ATP7B. The mammalian copper-transporting P-type ATPases, ATP7A and ATP7B are key molecules required for the regulation and maintenance of copper homeostasis. Menkes and Wilson diseases are caused by mutation in ATP7A and ATP7B respectively. This subfamily includes other copper-transporting ATPases such as: Bacillus subtilis CopA , Archeaoglobus fulgidus CopA, and Saccharomyces cerevisiae Ccc2p. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_CP045571.1\|WP_024894517.1\|111309_111750_+\|ComEA-family-DNA-binding-protein	gnl\|CDD\|378965	pfam12836, HHH_3, Helix-hairpin-helix motif. The HhH domain is a short DNA-binding domain.	2.02931e-24
NZ_CP045571.1\|WP_024894514.1\|107165_107696_-\|methylated-DNA--[protein]-cysteine-S-methyltransferase	gnl\|CDD\|223427	COG0350, Ada, Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair].	3.02293e-50
NZ_CP045571.1\|WP_153940355.1\|100015_103126_+\|CusA/CzcA-family-heavy-metal-efflux-RND-transporter	gnl\|CDD\|226220	COG3696, COG3696, Putative silver efflux pump [Inorganic ion transport and metabolism].	0
NZ_CP045571.1\|WP_024894519.1\|112726_113089_-\|DUF2782-domain-containing-protein	gnl\|CDD\|378588	pfam11191, DUF2782, Protein of unknown function (DUF2782). This is a bacterial family of proteins whose function is unknown.	2.02456e-25
NZ_CP045571.1\|WP_024894518.1\|111766_112699_-\|homoserine-kinase	gnl\|CDD\|235369	PRK05231, PRK05231, homoserine kinase; Provisional.	2.24417e-142
NZ_CP045571.1\|WP_024894515.1\|108021_108984_-\|DnaJ-domain-containing-protein	gnl\|CDD\|182347	PRK10266, PRK10266, curved DNA-binding protein.	7.2685e-97
NZ_CP045571.1\|WP_010640780.1\|116618_117881_-\|voltage-gated-potassium-channel-protein	gnl\|CDD\|236711	PRK10537, PRK10537, voltage-gated potassium channel protein.	8.013e-174
NZ_CP045571.1\|WP_153940350.1\|93342_93549_-\|cation-transporter	gnl\|CDD\|184298	PRK13748, PRK13748, putative mercuric reductase; Provisional.	1.89675e-14

>NZ_CP045571.1|WP_153940356.1|104273_106223_-|diguanylate-cyclase
MTTTSAGPEGAATVAFSEQDTLRLKQLGTTLRPRLAQLTEDLYNHIQSQLETSNLPGDADQAARLRAMQKDWLEKLLAGPYDGAFWDTQRHMGERHIELTIPLPQIWATFTFLRTSLTGEAIRAAVTEQTDPVAGITPLLRLLDACQYVMSTAYERKRLHDAILALRQLARVYDLEAFFHEAAKQAIMEAQADGAGLLCQEDGHQLQYRFFHGLPASYQAFARWSFPDHLGTSGAALQRGEPVYVSDYPQSIYAMPEFVDAGLQGSLAIPIPGPEGLQGVLAISWFQSQPPVRIPEDRWDHLRLITDLLGANLHREKLEMRMEGLATRDMLTGLPNRRVVTERITTAMARAERHQCLFALLFLDLDGFKPINDRLGHHVGDETLQQVAHDLRSALRGEDSVLRYAGDEFMVLAQDMTHISEVEAIAQRMVETVHRDVHKGELTLPLSASIGVSVYPFDDGSAEEIVHHADLAMYAAKQAGGDQWQFYDNDIGEALAERQALVHDLRHALDRGEFRLHWQPIVTLSPRQISGAEALLRWQHPTRGLLSPGEFLEILESLPLMQAVGHWIIETACAQAAQWHRQGHCLDVHINLAATQLEDKALLGFLKDTLPSRPKHPALLSGPSGDLAADRRQIHRASLGSGSPASCGP
>NZ_CP045571.1|WP_101536851.1|103163_103706_+|hypothetical-protein
MLKSILSALAIAGYVQADRANASGMGSMMGNMMEGNDHDHEGMRAMMSPENRGPMRTGMELFQVHAEVHRKVTFLPNGIHAVTISAVPHTVALLQAHVTQMYQRLAEDQPFPYPASRSVPVMFAHPTLYQRKLDYLKDGVAVTETSSDPEMIQVIHAHAREITRFVKEGMPAMMRGMMSS
>NZ_CP045571.1|WP_153940355.1|100015_103126_+|CusA/CzcA-family-heavy-metal-efflux-RND-transporter
MIKAVMRWCLNNPLLVVIASLVVIVAGVLSILSIPLEALPDISPTQVIVKTSYPGQAPQIIQDQITYPLETTLQEVPGTKAVRGYSMFGDSYVYVLFKGGTPIYQARNLVLQYLNQAQGQLPAGVTPALGPNSSGVDWIYEYALTDPGGSLNLAQLTTLQNWFLKFALQGIPGVAQVATVGGMEQEYQVVVFPNRLLAYNLTLPQVEAAIRAANGETSGSVVDMGESRYIVRTSGYIHSLKDLQQTPLGVRDGVPVTLQQVARVQLGPVLPSGIAELNGQSQVVGGIVMMNQGGNANALIQKIQQKLKSLQASLPAGVKVVTTYSQRPLIQRSIQTLSGKLLEECVAVLLVTLLFLLRIRSALVVLIALPIGILGAFIVMYALDIPANIMSLGGIAIAIGIMVDAPVVMIENMHKHMEKGEALNPWQTAGIAAMEVGPALFFSLLIIAVSFLPIFALSGQEGKLFAPLAFTKTFAIAAAAILAITLVPVLMAWFIRGKIPVERKNPLNRVLARWYRPVIHGVLQAPWMVVIGAVLVAATLVYPWQRLGTQLMPPLDEGTLLYMPVAQNPAISYGESAALLQLTDRIIKTFPEVKTVFGEAGRAQTATDQSPISMFDTVVTLKQPDHWPAHISMNKLRDQLNQALQIPGLSNNWTQPIKGRVDMLTTGLQTPLGLKITGQNLATLSLLGQKVQAVLQKVSGTQTAYAARVTGGRYIVVHTDRAAAARYGISVADVNRLVETAIGGKVLTTAVEGVQRFPVDLRYPRDRRQSLSALMDSRVTAPNGAQIPLAQLAQVDMVNGPAMLTSDDSQLNSWVTIDLKPGTSIGTYVARAKRMLAHQVHLPPGYTINWVGEYQSMHRANQRLQIVVPMVLLLIALLLYLNFRNVVEVAIVLVTLPFSLVGGLWLVYVLHYKLSVAVVVGFIALAGVAVEFGVVMLLYLDQALQHRRARDALQNWHDLQLAIMEGSMLRLRPLVMTFTLVVVGLLPIMLSEGTGADMMKRIAAPIIGGMLSATLLALLVIPALYALWQRRRLRLR
>NZ_CP045571.1|WP_153940354.1|98643_100023_+|efflux-RND-transporter-periplasmic-adaptor-subunit
MKFRQWTLPVGLLALGVALGAGGAWWLRTPSAVPNLTKSQRPSPNNSTDQRHILYWASPMNPKIHSNHPMKDNMGMAYIPVYAPGTNAQKPSGLHINSQMAQNLGVRLVQVQERQMGHTIHTVGTVAVDENRVYSVNPRFSGWVEQLRVRAVGDTVQRGQVLAEIYSPALYSAQQEYLIARRQQGRTADPALLAAARTKLQLLGMSRNEITALALHGHAERDVALRAPASGVIEKLNVHQGSYIAPQTELYQIANLDRVWVNVALYTYQLPWIQTGDSARLHLPAYPEERWKGSLSFLYPTLNAQNRTVTARLSVPNPEGKLRPGTYADATILARPEKSLAVPSSAVLHSSQGDFVMLGEGHGHFLPVQVRLGPAYRGWVAIPKGLRPGDRVVESAQFLLYSESQFQSVRARMLGANTARVDSASPVVAKNRSTPVSKKPKKSTPASMTNMNMGGKSHD
>NZ_CP045571.1|WP_153940353.1|97369_98647_+|TolC-family-protein
MDVNLFERLLAKNRIRLLAGIVLCCSTTTACADPLSLQNAQTIALRQNPGLGALTQKIVELKHQAVSVAQLPDPHLSLGAENLPLNSFSMNQQQMSMLSVGLSQTFPSFGKLGLEGRQTRVEAAAATDTLQGQSAELVLLLRRAWLQALYTDKAIMTVRHQEQLQAESVRAALALYRSARGSEANVLRAQLARDDLANDISKLQAERTHYLAQIAQILNLSQPPSIQNRWPHLPSPKTLRTAETRLLGQPLLRSAQAQSRAAQIGVQVAQRSYWPNVTVSAAYGQDFYPGSPNWLSVGVNLSLPIFPEDRQDQNVDAARARALQAQYRFDDQHLALIQQLRSTFARYTALKKEWTRTDERLVPRAQQAFSATLAAYTSGQAHMDAVLRTQNAVLRYALTRLQYRRDLALSVAELDFLTTQGRTTS
>NZ_CP045571.1|WP_170286679.1|96861_97131_-|hypothetical-protein
MRLCAERHALTTHRFGMGIHQHHAHAHAHAHARITLATRHVRHRHAHHGHPVHFNTGYTLWHRHRSIAHPGSNKEQGQYCQRTKVAAKF
>NZ_CP045571.1|WP_153940351.1|94029_96540_-|heavy-metal-translocating-P-type-ATPase
MDEKTRGQLEIGIDGMTCASCSARVERALGKLPGVTSASVNLATERAEVFFDPQQLNAARIAGAIRETGYTPVTDEIDLVVEGMTCASCVGRVERALRKQSGVLEAVVNLATERAHVRYIPAMISTEELASIVSAAGYAAHPVQEDEGQDGNETDQRRASLRAMGRDVIVAAVLAMAILVLSMGASFFPAFDRALMVTSPFAHFWEWVQFVLASIVLFGPGRRFFRPGLIAYRHLSPDMNSLVATGTGAAWAYSALVLVAPAWFPLDARHVYFDSAAVVIAAVLAGKYLEGLAKGRTSSAIRKLAGLQAKTAHRLDTNGIEHEVPISRLRTGERIVVRPGERIPVDGRVVERRAHVDEAMLTGEPLPSVKTMDDNVVGGTICQDGRLVVEATSVGHDTVLAHIIHLVESAQTGKLPIQGLTDRAVRVFTPVVLAIALATFGVWIVLTGNVSIALVAAVAVLVVACPCAMGLATPAAIMVGTGRAAELGVLFRKGEALETLSHVDTLLFDKTGTLTEGRPALVDQGGSDPAKALRLAAALELASEHPLGRAIVTAADERDMHLPTGKNFRSIAGYGIEGEVEGRMVRVGARRFMERENVLLGDSAETAAQRENGGRTVVFVAIDATLIGWLAIADRIKPEAYAVVQALRARGLQVAMVTGDGRATAQSVARQLHIEQVHAEVLPQDKAKVVSQLQEQGRRVAFVGDGINDAPALAQAHVGIALASGTDIAIEAADVTLTRGQLGEVVTALTAARRTLSNIRGNLFWAFFYNILLIPVAAGVAVPIGIHLNPMVAGVAMGLSSIFVLSNSLRLKRLKAYVPTVTPGAVQNTALKPAHS
>NZ_CP045571.1|WP_153940350.1|93342_93549_-|cation-transporter
MSDIHLKITGMTCEHCVRAVAKALEGVPGVEKADVTLEPGEAVVHGKADTTALTAAVKEEGYVAEVQG
>NZ_CP045571.1|WP_153940349.1|93075_93321_-|NrdH-redoxin
MYDPVLLYTSPGCPDCAAVRRYLEEHHVAYEERDVTAPGVAEEAKSRYGVRVAPITVIGCEAVWGTFAHQKPRLDELLTKP
>NZ_CP045571.1|WP_153940348.1|92747_92912_-|hypothetical-protein
MDEQSSRFLLKTDKSQAQLEDTNKVGKRAPHPPKFFLIMPQIEVIFAANHSNSA
>NZ_CP045571.1|WP_024894514.1|107165_107696_-|methylated-DNA--[protein]-cysteine-S-methyltransferase
MSLNESLDWHIHRCNTPLGEMLLVTDPQGTLRALDYWEDSQHSILADLGRLYGTDRITLTSGPLPTLIRHSLEAYWAGDLQALTVIPTKSAGTPFQQAAWAWLRTIPAGETRSYKEQAQGMNLPAAVRAVGHANSKNPIGIVVPCHRVIGSNGTLTGYAGGIDRKRWLLQHEGALS
>NZ_CP045571.1|WP_010640796.1|107718_108006_-|MerR-family-transcriptional-regulator
MVSTPIQVIEAELLEEGAFCFDLSRFCTLLHCAEGEAVQLVHYGVIHPEGSGPQHWRFRSLDLYRARLSRRLARDLEIDLAGAALAVDLLERLRH
>NZ_CP045571.1|WP_024894515.1|108021_108984_-|DnaJ-domain-containing-protein
MEYKDYYKILGVERGADADAIKAAYRKMARKYHPDVSKEANAEDRFKDLQEAYEVLKDPEKRTAYDQLGSNWRAGQDFRPPPGWGGQPGGFGGGGFGGADFGGNGGFSDFFESLFRQQHGGAGGFHGGGGGFRSQGEDSEASIQISLEDAAQGAQRDINLEMPTLGPDGRMRREARRLTVKIPKGIREGQRLRMAGQGSPGMGGGPNGDLYLQVHFQPHSKFRVEGADLYHDLHITPWEAVLGASVEVPTLEGSVRMKIPAGSSSGQKLRLSQKGLPGTSSKPAGDLYAIIQIVVPKNISDDEKALWTQLGEISSYHPRR
>NZ_CP045571.1|WP_031575890.1|109100_111230_+|UvrD-helicase-domain-containing-protein
MSDWSTLNPRQLEAVTLPPGPALVLAGAGSGKTRVLTSRIAHLLEEGVHPGEILAVTFTNKAARSMRERLDKMVAMELRGLWMGTFHGLAHRLIRLHHEALKLPADFQVLDSEDSQRLLRRLMREAQMDEKQWPPRAMAGRIGRWKDEGWGPEQVLRYEGPAAAAFVPIYQAYEVAKQRSGLLDFGDLLLYALKLWASPEILDHYQRRFQHILVDEFQDTNAVQYAWLKGLARHGQIFVVGDDDQSIYAWRGARVENLLRFGEDFAGARVVRLEQNYRSTAAILQAANAVIANNPERMGKTLWTAESGGEAVHLYTAYNEFDEARYVIGRIQQWQDQGGRRSDCAILYRSNAQSRAFEEVLVREGLPYRVYGGLRFFERAEIKDTLAYLRLTANRHDDASFERVVNVPSRGIGAVSVERLRNLAREKGLSLWQAAGALNQAKINGFLNLVDTLAEQTQEQDLDKRVEIILQHTALREWHSREGDRAEGRLENLDELINAARAYGQDWHADPQLGELAPQPGNMLSEFLTHAALEAGDGAGDAWEDCVQLMSLHSAKGLEFPLVFLVGLEEGLFPHQRSLEDGQGLAEERRLCYVGMTRAMRLLVLSHAESRRLHGSERMSMPSRFLREIPQELLQDLRPRARISRPAMALRPAAPEMPYPLGSRLQHPVFGEGTVLDYEAGGRQGRIQVQFSSGAKWLALGVVQLQQLP
>NZ_CP045571.1|WP_024894517.1|111309_111750_+|ComEA-family-DNA-binding-protein
MKIWMGMLLGVILSLFALPLWASVNINTADVAALDSLPGIGPAKAQAIVEYRKAHGSFKTLDDLARVHGIGSKLLERLRPSLALDGQTTALSSVAGCSSGKAASRKKPIPAGEERAIRQGSHGYILDGGPDSNAFHYRHFSLQESS
>NZ_CP045571.1|WP_024894518.1|111766_112699_-|homoserine-kinase
MSVYTNVSDQELAQFLEDYDLGKAISLTGISAGVENSNYFLDTDQGRFVLTLFERLSAAKIPYFLDLTDWLSTHGIPCPRPMHARSGKSLNSLCGKPAAIVQCLQGRSIEGRAPTLTEIRALGQLLGQMHLAGEDFPQRQPNPAGLAWMQETARHLVPHLDPADNQIIADELAYQSHIQREKLPGGVIHADLFPDNVLFAEQQISGTIDFYYAGDDAWLYDLAVVANSWCARPDGQLDPSLSVALWEAYVATRPLRDDEAPLWFAMLRIAALRFWLLRLDAVHFRRPGAITFCKDPEEYHRILLQRRQGL
>NZ_CP045571.1|WP_024894519.1|112726_113089_-|DUF2782-domain-containing-protein
MSTRIMITTMVAALALGVAATALADTDAALPNSAQQNIQKLHLPKLAPQKIGPNAEIKAPTGSKIEEYKVNGKVYMVKVIPPKPFPPYYLEDKGGTGRFTEVPQTAAEHLSVPQWIIFRW
>NZ_CP045571.1|WP_024894520.1|113106_113826_-|TIGR00730-family-Rossman-fold-protein
MRAHLEEEKLRDGGEGRLTREAWKIFQIMAEFVRGYEKLVDVDPCVSIFGSARLGPDNPWYLKTEEIAEKLSNAGFSVLSGGGPGIMEAANKGAFHGTGYSIGLNIELPHEQHSNPYQDIAISFEHFYSRKVMFMKYAVAYVVMPGGFGTLDELAECLTLVQTGKTRRMPIILVGSDFWNGLIVWWQEAMLGLGTINPEDLHLITVIDDPDEVVSAIFNHYEKRGFAPSAAETEALLNL
>NZ_CP045571.1|WP_024894521.1|113895_116622_+|DNA-polymerase-I
MPQDPRILVDASSFLYRAFHALPDLRAPDNLPTGAIFGVANMLRRLAKEYPSDEIIVVFDAPGGTFRDRLYPEYKAQRPAMPEDLRAQIPLLHEWIQATGLPLVLVPDVEADDVIGTLAGSAQAGQQVIIVTGDKDMAQLVNDQVTLLDTMKGVKTDVAGVWERYGVAPERIADLLALTGDKVDNIPGVPGAGPKTAAKWIQQYGSLDGVLAHADEIGGKIGEALRASLDYLPLSLDLTTIRRNLHLPEQSYQRVPENTQKLRSLALRLGFHAWLKEYPAEPGTENNTEVSVNESAAGGLMPIDRSRYRAITTPAALENLLQKLQQADLVALDTETTALDPLNADLVGISCAWQEGDQIEAVYIPVGHRDDSTQLVLDHVLATLRPWLENPQAAKLAQNAKYDWRVFWRYDIHPAGLCRDTLLESYILDSSQNNHDLDTLAQRHLQHQNITYEEVAGKGKAARNFADVPVSEALPYAAEDADVCWRIDAQLWPRFANEAGLQRVLMDIEMPLVLVLARMEQAGVRVDKEQLKTLSMELGRDMAACEAQAFKSAGQSFNLGSPKQIQEILFDKMQLPVLKKTPGGQPSTSEDVLAQLAVQADLPRLILEYRGMAKLKNTYADALPEMINPRTGRVHTHFQQAVAATGRLSSSAPNLQNIPVRTEQGRRIRQAFVAEDGFYLLSADYSQIELRIMAHLSRDARLLQAFAEGQDIHAATAAEVFNLAPEAVDSDARRAAKAINFGLIYGQTPYGLAQQLGIEQSAARAYMDRYFERYPGVLTYMEQTRVLARQQGYVETLFGRRLYVPEIRSSNAARRNYAERAAINAPMQGTAADLIKKAMIAVDAWLQETPARGRMILQVHDELILEVPESGLEAARAALKELMEGVADLAVPLLVGLGVGKHWDAAHG
>NZ_CP045571.1|WP_010640780.1|116618_117881_-|voltage-gated-potassium-channel-protein
MSEKFSHTPHPWHILRPSWRNRWRGRAERWARRLQLDRWYPHTPIAAAVGFLGLFNILPAIGQLLGLSYVGSLADMSSGFVLDAFRGLPQGAAGIILLIMSLGLLFRSRFAWAIVLTIASAVLAVGIYRHPQHISALLYYNAVLVFFLWIFRGRFNHSSLATGTLFALVGAIMVIGYGVFGAYILGDGFKPHIHSLTGALYFSIVTMSTVGYGDVLPVSNEARLFVVSLIVLGITVFATSLSAIIVPAINNRLQSALQGEKRRMTLKNHYIIAGDTPLARNSYRELKSRNLPVIVIMGHQPDDSIYQADDLIIGDSSDTDILRSAGAEQALAVLALRADDSENAFVVLAVKEMEGSAKTVAAVNDSKNLGRVRRVQPDMIIAPQVLGGELLAMALNGEQLDNNAVMKMFRFSTGATPSKG

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Click the colored protein region to show detailed information

Crispr_ID: NZ_CP045571_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045571_2

634677-634823

Orphan

Consensus_repeat	Method
ATCGTCTACCGGGTAGACGA	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP045571_2

>merge|NZ_CP045571|2|634677-634823|PILER-CR
TCGCCTACCGGGTAGACGATTTTTTAGAGCAGCGTTCAGCGGGAATACGCTTTTATTTACCGATTCTGGGTCCAGCGTCTACCGGGTAGACGCCCGAACACAGGCCCGATTGGGTGAAAAATGCGAGATCGTCTACCGGGTAGACGA

>NZ_CP045571|2|2|634677-634823|PILER-CR
TCGCCTACCGGGTAGACGAT	TTTTTAGAGCAGCGTTCAGCGGGAATACGCTTTTATTTACCGATTCTGGGTCCA
GCGTCTACCGGGTAGACGCC	CGAACACAGGCCCGATTGGGTGAAAAATGCGAGA
TCGTCTACCGGGTAGACGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045571.1\|WP_010641843.1\|645467_645719_-\|type-II-toxin-antitoxin-system-prevent-host-death-family-antitoxin	unknown	unknown	gnl\|CDD\|171099
NZ_CP045571.1\|WP_080707873.1\|631090_631303_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045571.1\|WP_153940424.1\|638684_639605_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045571.1\|WP_031575425.1\|629975_630371_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045571.1\|WP_153940417.1\|627956_629201_-\|ParB/RepB/Spo0J-family-partition-protein	unknown	unknown	gnl\|CDD\|319251
NZ_CP045571.1\|WP_081576824.1\|645861_647922_-\|transglycosylase-domain-containing-protein	unknown	unknown	gnl\|CDD\|227289
NZ_CP045571.1\|WP_170286687.1\|643728_643902_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045571.1\|WP_153940423.1\|636110_638162_-\|DNA-topoisomerase-3	unknown	unknown	gnl\|CDD\|236078
NZ_CP045571.1\|WP_031575399.1\|643193_643499_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045571.1\|WP_153940422.1\|632973_633567_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045571.1\|WP_075324056.1\|634050_634347_+\|putative-addiction-module-antidote-protein	unknown	unknown	gnl\|CDD\|188241
NZ_CP045571.1\|WP_153940426.1\|643888_644419_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045571.1\|WP_153940416.1\|626418_627360_+\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|238923
NZ_CP045571.1\|WP_140390914.1\|644700_645189_+\|DUF2442-domain-containing-protein	unknown	unknown	gnl\|CDD\|378424
NZ_CP045571.1\|WP_153940419.1\|630465_631119_-\|S26-family-signal-peptidase	unknown	unknown	gnl\|CDD\|371097
NZ_CP045571.1\|WP_153940418.1\|629202_629973_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|224113
NZ_CP045571.1\|WP_170286686.1\|639676_640540_+\|RNA-directed-DNA-polymerase	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|239569
NZ_CP045571.1\|WP_153940421.1\|631606_632977_-\|conjugal-transfer-protein-TraB	unknown	unknown	gnl\|CDD\|237523
NZ_CP045571.1\|WP_010641842.1\|645216_645471_-\|Txe/YoeB-family-addiction-module-toxin	unknown	unknown	gnl\|CDD\|284238
NZ_CP045571.1\|WP_153940420.1\|631265_631559_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP045571.1\|WP_081576824.1\|645861_647922_-\|transglycosylase-domain-containing-protein	gnl\|CDD\|227289	COG4953, PbpC, Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell envelope biogenesis, outer membrane].	3.40579e-156
NZ_CP045571.1\|WP_140390914.1\|644700_645189_+\|DUF2442-domain-containing-protein	gnl\|CDD\|378424	pfam10387, DUF2442, Protein of unknown function (DUF2442). This family of bacterial and fungal proteins has several members annotated as being putative molybdopterin-guanine dinucleotide biosynthesis protein A; however this could not be verified. Hence the function is not known. This family also includes the DUF3532 that was found to be related and was merged into this family. Members of this family also fall into the NE0471 N-terminal domain-like superfamily, a family of proteins with a unique fold in SCOP:143880.	3.48323e-06
NZ_CP045571.1\|WP_075324056.1\|634050_634347_+\|putative-addiction-module-antidote-protein	gnl\|CDD\|188241	TIGR02684, conserved_hypothetical_protein, probable addiction module antidote protein. Members of this strictly bacterial protein family are small, at roughly 100 amino acids. The gene is almost invariably the downstream member of a gene pair. It is a predicted DNA-binding protein from a clade within Pfam helix-turn-helix family pfam01381. These gene pairs, when found on the bacterial chromosome, are located often with prophage regions, but also both in integrated plasmid regions and in housekeeping gene regions. Analysis suggests that the gene pair may serve as an addiction module. [Mobile and extrachromosomal element functions, Other].	4.87643e-37
NZ_CP045571.1\|WP_153940417.1\|627956_629201_-\|ParB/RepB/Spo0J-family-partition-protein	gnl\|CDD\|319251	cd16393, SPO0J_N, Thermus thermophilus stage 0 sporulation protein J-like N-terminal domain, ParB family member. Spo0J (stage 0 sporulation protein J) is a ParB family member, a critical component of the ParABS-type bacterial chromosome segregation system. The Spo0J N-terminal region acts in protein-protein interaction and is adjacent to the DNA-binding domain that binds to parS sites. Two Spo0J bind per parS site, and Spo0J interacts with neighbors via the N-terminal domain to form oligomers via an Arginine-rich patch (RRXR). This superfamily represents the N-terminal domain of ParB, a DNA-binding component of the prokaryotic parABS partitioning system. parABS contributes to the efficient segregation of chromosomes and low-copy number plasmids to daughter cells during prokaryotic cell division. The process includes the parA (Walker box) ATPase, the ParB DNA-binding protein and a parS cis-acting DNA sites. Binding of ParB to centromere-like parS sites is followed by non-specific binding to DNA ("spreading", which has been implicated in gene silencing in plasmid P1) and oligomerization of additional ParB molecules near the parS sites. It has been proposed that ParB-ParB cross-linking compacts the DNA, binds to parA via the N-terminal region, and leads to parA separating the ParB-parS complexes and the recruitment of the SMC (structural maintenance of chromosomes) complexes. The ParB N-terminal domain of Bacillus subtilis and other species contains a Arginine-rich ParB Box II with residues essential for bridging of the ParB-parS complexes. The arginine-rich ParB Box II consensus (I[VIL]AGERR[FYW]RA[AS] identified in several species is partially conserved with this family and related families. Mutations within the basic columns particularly debilitate spreading from the parS sites and impair SMC recruitment. The C-terminal domain contains a HTH DNA-binding motif and is the primary homo-dimerization domain, and binds to parS DNA sites. Additional homo-dimerization contacts are found along the N-terminal domain, but dimerization of the N-terminus may only occur after concentration at ParB-parS foci.	1.94389e-30
NZ_CP045571.1\|WP_010641842.1\|645216_645471_-\|Txe/YoeB-family-addiction-module-toxin	gnl\|CDD\|284238	pfam06769, YoeB_toxin, YoeB-like toxin of bacterial type II toxin-antitoxin system. YoeB_toxin is a family of bacterial toxins that forms one component of the type II toxin-antitoxin system in E. coli whose antitoxin is represented by YefM, found in pfam02604. The plasmid encoded Axe-Txe proteins in Enterococcus faecium act as an antitoxin-toxin pair. When the plasmid is lost, the antitoxin is degraded relatively quickly by host enzymes. This allows the toxin to interact with its intracellular target, thus killing the cell or impeding cell growth. These toxins are highly potent protein synthesis inhibitors, specifically blocking the initiation of translation. In the case of YoeB, it binds to the 50 S ribosomal subunit in 70 S ribosomes and interacts with the A site leading to mRNA cleavage at this site. As a result, the 3'-end portion of the mRNA is released from ribosomes, and translation initiation is effectively inhibited.	1.79717e-43
NZ_CP045571.1\|WP_153940423.1\|636110_638162_-\|DNA-topoisomerase-3	gnl\|CDD\|236078	PRK07726, PRK07726, DNA topoisomerase 3.	0
NZ_CP045571.1\|WP_010641843.1\|645467_645719_-\|type-II-toxin-antitoxin-system-prevent-host-death-family-antitoxin	gnl\|CDD\|171099	PRK11409, PRK11409, YoeB-YefM toxin-antitoxin system antitoxin YefM.	3.14456e-23
NZ_CP045571.1\|WP_153940416.1\|626418_627360_+\|EAL-domain-containing-protein	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	2.87977e-113
NZ_CP045571.1\|WP_153940419.1\|630465_631119_-\|S26-family-signal-peptidase	gnl\|CDD\|371097	pfam10502, Peptidase_S26, Signal peptidase, peptidase S26. This is a family of membrane signal serine endopeptidases which function in the processing of newly-synthesized secreted proteins. Peptidase S26 removes the hydrophobic, N-terminal, signal peptides as proteins are translocated across membranes. The active site residues take the form of a catalytic dyad that is Ser, Lys in subfamily S26A; the Ser is the nucleophile in catalysis, and the Lys is the general base.	1.04958e-12
NZ_CP045571.1\|WP_153940418.1\|629202_629973_-\|AAA-family-ATPase	gnl\|CDD\|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	9.77096e-38
NZ_CP045571.1\|WP_170286686.1\|639676_640540_+\|RNA-directed-DNA-polymerase	gnl\|CDD\|239569	cd03487, RT_Bac_retron_II, RT_Bac_retron_II: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA branches out from a small ssRNA molecule via a 2'-5'phosphodiester linkage. Bacterial retron RTs produce cDNA corresponding to only a small portion of the retron genome.	1.59507e-70
NZ_CP045571.1\|WP_153940421.1\|631606_632977_-\|conjugal-transfer-protein-TraB	gnl\|CDD\|237523	PRK13825, PRK13825, conjugal transfer protein TraB; Provisional.	1.26386e-113

>NZ_CP045571.1|WP_075324056.1|634050_634347_+|putative-addiction-module-antidote-protein
MSEKLSTFDPAEGLASDAAIAAFMADAFESADAGYIAHALGVVARAKGMAQIAGETGLSREQLYRSFSERGNPTLKTTLAVMKVLGIELTAKPGPQGR
>NZ_CP045571.1|WP_153940422.1|632973_633567_-|hypothetical-protein
MNPIVVFDLDGVLLDFESAWAQCASWELGRPIQKVSEAYDLQERFALSARECHRVWSAFHRDAWWERVPSHGSAWDAVCNVEAAGGSVWAVTNVDAQWIHARAISLGGLIPSGRIICLGEDASAHDRVKILEALHAQAFVDDQAANVNAAVGIIAAPVFLHRAYQGQEEPAHGVTVIDDLLDFPVVVEPLFKAARAA
>NZ_CP045571.1|WP_153940421.1|631606_632977_-|conjugal-transfer-protein-TraB
MTAQSSTVYPVDDSRRKSALVSRFAIPALLGALVGVLAWPHAIWLAPLALLLLPVLNKRSWMAPFCLMFGYHMATTYGLIKGTSVFFPHSGLFLGIGFWSLSSLAFALPYLAYPYIALYFRGGGLAGGSLAGGGFGAVTATIITSAVSTILPPLGIIGWTSPWLGAVAAGPTGILLTILGIFALGYWERKNQDFPVRLLMAGIVVFNLWLLGFVFPALAALAERVPALVDMMGHPLPTAPAGWVGINTHLGRLRSNLSYVDASMEMAPKILADLHAGDKVVLLPETLAGPWLPGTRAIWRPVIRWTARHPGQTVLLGADVPLTGCEPHGRDLRPAKGYLDALVKIQDGHQTVLPDHIPVPFSMWHPWHPRDSFRMAPFSRKPETTEIDGKKVGYLICYEQLLMWPALDLYPHGIQVLLAPANDWWARGTDIPAIQRASAKAWAAFFGVPVLFAVNQ
>NZ_CP045571.1|WP_153940420.1|631265_631559_-|hypothetical-protein
MGNPSDPCDPLLAWKPVLDSLDDKRRERLKDLLKTHLSRPLTAQQRIAKWEKVLSADYSRIPAEQHIATLEASLEEAITVLKERVREQSSSASHRSA
>NZ_CP045571.1|WP_080707873.1|631090_631303_-|hypothetical-protein
MSNPLRQVIARLDQRLIAFFERPSPRKVAEAMLWGATHIEWLFFFPFRLLTGPARFFLERRHAKNVRHHR
>NZ_CP045571.1|WP_153940419.1|630465_631119_-|S26-family-signal-peptidase
MQRMSATIAKRLLWWSAWAIVGVLVLNAAVGLWMQYQHLVFNDSTCEPIGIYKLLGSPYPLHDGELVEVEIPGPTHHAAVAEGLKYHWFPAGQPWIKEIAAVPGQTVKLSRAGDWVSPGDASPADSSPAGGGPADGEAGHYLPNSHVDRWTPGHHHRIVHYPFGTYHLKRGQVWLYAPGNYAFDSSYYGPVPETSILQRAVPWWTIPGSQFWLQKGD
>NZ_CP045571.1|WP_031575425.1|629975_630371_-|hypothetical-protein
MLTPSLFNGMPYAGESTVIPLKMHLYIQALAFVQGMTLRAVHEDCASRFLAEKAWEKGLRWRDGHRPALADTEWVEVNVRIPCDLADNLVEVSHRNGVGLPDVLYTMLYWYSWVLYPPLHEQERRKAQEER
>NZ_CP045571.1|WP_153940418.1|629202_629973_-|AAA-family-ATPase
MPQIITVTNQKGGVGKTALAVHIAAYASMAAKKKTLLVDMDGQRNATFITTGEPNGRGKSVLELWDGDTSLEFQDTRFGDLKILPGHQHVHLVEKQGLKAGQEAMSRLLKIDFDVVVIDTPPAAGVQQLAPLYLGGLLVAPVEPDLLALQGLTSLLKVWREIASQVDLGLSLVINKRVLNSTNQQMVVDAITESGFGQHVLPVHLTNRLIVSNALKQGMPVWKLDPKDAAAAKWAMACKMILETDRVPTEETVKEG
>NZ_CP045571.1|WP_153940417.1|627956_629201_-|ParB/RepB/Spo0J-family-partition-protein
MAKVDLSENLFDEMKRTLAEMAGDSGETDAKANRLPGRRLPGQKAAPADEQNTVSGGTVGSGAASALFLELSEIEPDPEQPRKTFVASGAQDAIDNDLELLKESILQHGVLQPIAVRHVVSGRYRIIAGERRWRASMAARDSGQPCRRKGYDLSRIPAVILEPDTDADRLEMQLVENLARADMTPVDTAKAVKQLMDSLAPKPSLSDLGKRLGRSKAWVHQMLSLGSEDAQAVAEYLGVPLESIGQTDISRMKGWMKDEDKRIVLDAIRASLQAGETLSRVLVDREESRYERGLSGKPQEVDMQQENGAVRAFDANGEEVDLSTIDMHNVDSDEDIEDGGAVDENGVVVGDPADDAQEDGTLPGAPLPRASLPNQVTVTLPRPLLERAFEKAGRELPGTMGTVEIIEVLELVLN
>NZ_CP045571.1|WP_153940416.1|626418_627360_+|EAL-domain-containing-protein
MPLKPMNDQNVFYSTDEFPQAILASWAPILENRANCPRSARIIAHHRPESPPTIIQNDCPRWARIRSQAIDNEEFVLHYQPKVNLASGKVVGAEALIRWNDPRTGLVPPDKFIPILEETGLISEVGRWALRRAVEDYLRWRATGLEAVRIAVNVSPLQLRNPGFVAEIERKIGIGAHAADGLELEITESMIMEDVKHSVSILRTIRDMGVHVTIDDFGTGFSSLGYLSKLPLDTLKIDRSFVTDITAGPQGLALVTTIISLAHALKLKVVAEGVETEQQYSLLHLLSCDEMQGYLFSKPVPVEDFEKRFLGRM
>NZ_CP045571.1|WP_153940423.1|636110_638162_-|DNA-topoisomerase-3
MKVYIAEKPSLGKGIAEYLPGPKNKGNGFIQCGSDTVVTWCFGHIFEQEEPDFYTPDDVPTTPKGKKKWRFEELPIFPEQWKKRAKDDAKAQIKVIRELLKKASSVVNAGDPDREGQLLVDEILEELRWKGPTQRIWLAALDEQSVRKALASLKDNREYQNLSNSAEARARADWLMGMNLTRAFTLRNSGAGVVSVGRVQTPTLALVVARDEKIEHFKPKDYYVPRIYTGFWAAWDLREDFEGVDAEGFLTDRKAADRLATQAKADGKATVKDFTSDEKQQQAPLGFSLAELQKVCSAKLGMSAQNVLDAAQALYEEHKAATYPRTDCRYLPEEQHGDAGQILSGLAKAGFADLVKAADSNRKSAIWNTGKVTAHHAIIPTGSMQGSMSPAVAKVYEIIVRSYLAQFYPPYVYRAIKALLTCTGEDWKATANIPVSAGWKAVYGMTDDDNDDTPAQPIPALKKGQVLTVQDADVQAKQTKPPARFTDGSLIEAMSNIHKVVEDEAAKAKLKETSGLGTEATRASIIETLLTRGFMERKGKQILSTQAGRALVHALPKDLTDPVLTARWEDALSSVSEGRVTLQQFEEAQRKFVSRMIEAAKAATIAVGQARSATSARGKASTGKMRGGAAKAGPSCPDCKKPTITLKTKKGDSFFKCEGCQSCWWPDKQDAKKLGTKWSEKKT
>NZ_CP045571.1|WP_153940424.1|638684_639605_+|hypothetical-protein
MNSELVTVLTEQLDPAGCEVINLPARIWVFGGPTEPSSEPAGSLRDCFWRRTLKSTFNRPWAEHLARPEDFDDWWAFSGYSDLLTFERDACFLARAIILFVESPGSLAELGCLASHDSILPQVLTVVQRQYCEQGSRRSFLRLGPLNRVQSHGAECVIGTNQETELPDDDFDAIVETIDEWLKTNPQRTRFDPNKPAHIFLIAADLVDLMLISKQTEIDAVLKFYGVNLDEQILAQHLELLSFFKLIQKEVRGREIFWVRAPGSDAPWVDHKAKSGGRFFREKFKIYAEEYVNGKIRLKSVYGRLP
>NZ_CP045571.1|WP_170286686.1|639676_640540_+|RNA-directed-DNA-polymerase
MIATAPHRYKSHFIEKRHGRGKRLISQPTAELKYFQRWLVDNELNQLPVHDAATAYRKGRSILDHATPHAKQRYLLKLDFKDFFPSLNEHALRHCLERDCNYSEEEIEILCNLLLKSASIEGGPLQLSIGAPSSPFISNYLMWEFDIAMQQYCEVMGVMYSRYADDLAFSTDTPRLLDKVFDTVQKILASISYLPLILHPDKTVNVSKKRRRLLVGLTLANDGNVSIGREEKRRLRAALHAYTQGRLPCDEVARLAGMLSFVWSIDPKFVENLCQRHGFSRISDLLR
>NZ_CP045571.1|WP_031575399.1|643193_643499_-|hypothetical-protein
MRRISNLAFNQEFPEASGLSGIPADNQVRISRDTGNPYDRDAVGIWLGGHPKTPIGWLYRKDGNRDAVLQKLDAGGEITGHIEQRSRRKGEKPRKVVVFWL
>NZ_CP045571.1|WP_170286687.1|643728_643902_+|hypothetical-protein
MNYEEIEIPDELLCGGAFIEDGAPDLLIAAAWAINGYRCPVDHLQQAEPEEDIDDAE
>NZ_CP045571.1|WP_153940426.1|643888_644419_+|hypothetical-protein
MMRSESTLNAIPQDLRKELVLLADLLPEQSPLPYTKAKLLVLSWSRLGQDALAWAGANLIIKIDPAPYESGDLAYGPTPIQTVNRSVDLWKPFSPEHWREHVRGMSLFDLAVYLKLKVGTWGTTPIARRRHVTKDRLDGIGLGCQIHPTRSTASIFLCGERSLLEIVETDLADQIK
>NZ_CP045571.1|WP_140390914.1|644700_645189_+|DUF2442-domain-containing-protein
MGKPVGITRRYSLQSKVPGVYPGSVLSSFRLSGPAVSRIVLDWRKSAPIRITGNAWEFLRKKYRAQGKRHPAQGIIRSLKTSLGGSNQSLRKAPQKQGIFVSCVEFPWFKQATVEQITTIERQSSAHLYWPLLDVDLAVESIRSPALLPLVAKPNPSFQRTR
>NZ_CP045571.1|WP_010641842.1|645216_645471_-|Txe/YoeB-family-addiction-module-toxin
MKLVFADETWEDYLFWQKQDRKMIERINKLIRETQREPFGGIGKPEPLKHAFSGFWSRRITDEHRMVYRVEGDQLQIAQLRFHY
>NZ_CP045571.1|WP_010641843.1|645467_645719_-|type-II-toxin-antitoxin-system-prevent-host-death-family-antitoxin
MDAITYTKVRANLASAMDRVCDDHEALIITRNGEQSVVMLSLADYKALEETAYLLRTPANAKRLLAAAAQLNAGKGVELKLSM
>NZ_CP045571.1|WP_081576824.1|645861_647922_-|transglycosylase-domain-containing-protein
MSGRRTDRIFSSILRGGRRCLWPRGRYAWWRRCGHWLLLSIILVAVIAWFMPPDTQTLKQEGRIIYDRHGHVLSMFLNHQQQWAFATPAKRVSPVLIQMLIAIEDHNFAWDPGIDPLAIIRAAGQMIMAGHVVSGASTLTMQVTRMLHPAPRTLPVKIVEALQAISLYEHYSKSAVLGMWLSLAPEGSNIQGIEAAAHAWFNQSPRTLGPAQAAFLVMMVRNPNRLNPLTHPRAALATRNQILREAQRRGIISKAALERALATALPQRLYPMPLLSPQVASTLPSGTHSTIDAPMDRAVADIAQHALQQMAPSESIAIVVVSLKTKGIRAIYSGDWGNVQRDGFVDMTRAIRSPGSALKPFLYGLGFAAGIIRPSTNVADFPSNFGAYEPNDYNDRYMGVVTATTALRRSLNVPAVDLIEAYGPLRFAAHLRAAGTQLLLPYGADPALPLALGGAGISMRRLLALYAGLANDGVVERLHLIAGQHRRARRLLSPYAAEDVTAILNRSFPFGGPGGIAWKTGTSAGNRDDWAMGYNHRYAAAVWIGQPNGAALPGDTALAAIPILAKVFSILPGQPIDIHPTTRSLTLQRQPMGTLLEIASPAPGSQLTVGEPVSIRIIGGNRPFHFLLDGRPLDSNPALRSVDWTPAVAGFYQLSVLDASGQLVKRALRAVLPISAANAEWGNNVR

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Click the colored protein region to show detailed information

Crispr_ID: NZ_CP045571_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045571_3

1459443-1459581

Orphan

Consensus_repeat	Method
AAAGTTACCAACTTTATTTG	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP045571_3

>merge|NZ_CP045571|3|1459443-1459581|PILER-CR
GTTACCAACTTTATTTGCACAAAATTTAGCGGGTCTTGGGCTCGATCAGACATAAAGTTACCAACTTTATTTATTTTTGAAAATTTCGATGTGCCAATTTTACTGGCTTAGGCCAGATAAAAGTTACCATCTTTATTTG

>NZ_CP045571|3|3|1459443-1459581|PILER-CR
GTTACCAACTTTATTTGCACAAAATT	TAGCGGGTCTTGGGCTCGATCAGACATAAAGTTACC
AACTTTATTTATTTTTGAAAATTTCG	ATGTGCCAATTTTACTGGCTTAGGCCAGATAAAAGTTACC
ATCTTTATTTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045571.1\|WP_153940913.1\|1462045_1463371_-\|porin	unknown	unknown	unknown
NZ_CP045571.1\|WP_153940575.1\|1466844_1468551_-\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	unknown	unknown	gnl\|CDD\|273793
NZ_CP045571.1\|WP_170286704.1\|1450407_1450878_+\|transposase	unknown	unknown	gnl\|CDD\|376980
NZ_CP045571.1\|WP_139112156.1\|1466354_1466729_-\|SWF/SNF-helicase-family-protein	unknown	unknown	gnl\|CDD\|350180
NZ_CP045571.1\|WP_153940568.1\|1448512_1449544_+\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|226077
NZ_CP045571.1\|WP_153940574.1\|1456207_1457827_+\|glucose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|234679
NZ_CP045571.1\|WP_153940573.1\|1453612_1454509_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_CP045571.1\|WP_153940577.1\|1468947_1469718_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|350677
NZ_CP045571.1\|WP_153940570.1\|1450897_1451173_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274599
NZ_CP045571.1\|WP_065973872.1\|1468551_1468752_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045571.1\|WP_153940572.1\|1452445_1453306_-\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|235548
NZ_CP045571.1\|WP_012387019.1\|1454729_1455944_+\|ISL3-family-transposase	unknown	unknown	gnl\|CDD\|376574
NZ_CP045571.1\|WP_081576759.1\|1459730_1460006_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045571.1\|WP_153940578.1\|1469717_1470065_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045571.1\|WP_065973799.1\|1457923_1459138_-\|ISAzo13-family-transposase	unknown	unknown	gnl\|CDD\|369439
NZ_CP045571.1\|WP_051690708.1\|1470093_1470540_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|319786
NZ_CP045571.1\|WP_139112155.1\|1463951_1464335_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045571.1\|WP_153940571.1\|1451328_1452402_-\|C4-dicarboxylate-ABC-transporter	unknown	unknown	gnl\|CDD\|187759
NZ_CP045571.1\|WP_153940567.1\|1448229_1448391_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045571.1\|WP_065974094.1\|1464331_1466311_-\|type-IIA-DNA-topoisomerase-subunit-B	unknown	unknown	gnl\|CDD\|235501

Protein	Function_ID	Function_description	E-value
NZ_CP045571.1\|WP_153940575.1\|1466844_1468551_-\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl\|CDD\|273793	TIGR01766, Putative_transposase_MJ0751, transposase, IS605 OrfB family, central region. This model represents a region of a sequence similarity between a family of putative transposases of Thermoanaerobacter tengcongensis, smaller related proteins from Bacillus anthracis, putative transposes described by pfam01385, and other proteins. [Mobile and extrachromosomal element functions, Transposon functions].	9.35801e-07
NZ_CP045571.1\|WP_170286704.1\|1450407_1450878_+\|transposase	gnl\|CDD\|376980	pfam03050, DDE_Tnp_IS66, Transposase IS66 family. Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens.	2.29473e-16
NZ_CP045571.1\|WP_153940568.1\|1448512_1449544_+\|IS110-family-transposase	gnl\|CDD\|226077	COG3547, COG3547, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	8.75669e-43
NZ_CP045571.1\|WP_153940574.1\|1456207_1457827_+\|glucose-6-phosphate-isomerase	gnl\|CDD\|234679	PRK00179, pgi, glucose-6-phosphate isomerase; Reviewed.	0
NZ_CP045571.1\|WP_153940573.1\|1453612_1454509_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	4.11757e-42
NZ_CP045571.1\|WP_153940577.1\|1468947_1469718_-\|hypothetical-protein	gnl\|CDD\|350677	cd17919, DEXHc_Snf, DEXH/Q-box helicase domain of DEAD-like helicase Snf family proteins. Sucrose Non-Fermenting (SNF) proteins DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	1.58578e-05
NZ_CP045571.1\|WP_153940570.1\|1450897_1451173_-\|hypothetical-protein	gnl\|CDD\|274599	TIGR03481, HpnM, hopanoid biosynthesis associated membrane protein HpnM. The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins are members of the pfam05494 family of putative transporters known as "toluene tolerance protein Ttg2D", although it is unlikely that the members included here have anything to do with toluene per-se.	6.3969e-11
NZ_CP045571.1\|WP_153940572.1\|1452445_1453306_-\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|235548	PRK05657, PRK05657, RNA polymerase sigma factor RpoS; Validated.	7.76326e-69
NZ_CP045571.1\|WP_012387019.1\|1454729_1455944_+\|ISL3-family-transposase	gnl\|CDD\|376574	pfam01610, DDE_Tnp_ISL3, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS1165.	5.27763e-94
NZ_CP045571.1\|WP_065973799.1\|1457923_1459138_-\|ISAzo13-family-transposase	gnl\|CDD\|369439	pfam07592, DDE_Tnp_ISAZ013, Rhodopirellula transposase DDE domain. These transposases are found in the planctomycete Rhodopirellula baltica, the cyanobacterium Nostoc, and the Gram-positive bacterium Streptomyces.	0
NZ_CP045571.1\|WP_051690708.1\|1470093_1470540_-\|hypothetical-protein	gnl\|CDD\|319786	cd02587, HAD_5-3dNT, 5'(3')-deoxyribonucleotidase. This family includes cytosolic 5'(3')-deoxyribonucleotidase (cdN) and mitochondrial 5'(3')-deoxyribonucleotidase (mdN). cdN and mdN specifically dephosphorylate the deoxyribo form of nucleoside monophosphates helps maintain homeostasis of deoxynucleosides required for mitochondrial DNA synthesis. Their preferred substrates are dUMP and dTMP. cdN also dephosphorylates dGMP and dIMP efficiently. They can also dephosphorylate the 5'- or 3'-phosphates of pyrimidine ribonucleotides. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.0914e-16
NZ_CP045571.1\|WP_065974094.1\|1464331_1466311_-\|type-IIA-DNA-topoisomerase-subunit-B	gnl\|CDD\|235501	PRK05559, PRK05559, DNA topoisomerase IV subunit B; Reviewed.	0
NZ_CP045571.1\|WP_153940571.1\|1451328_1452402_-\|C4-dicarboxylate-ABC-transporter	gnl\|CDD\|187759	cd09319, TDT_like_1, The Tellurite-resistance/Dicarboxylate Transporter (TDT) family. The Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes members from all three kingdoms, but only three members of the family have been functionally characterized: the TehA protein of E. coli functioning as a tellurite-resistance uptake permease, the Mae1 protein of S. pombe functioning in the uptake of malate and other dicarboxylates, and the sulfite efflux pump (SSU1) of Saccharomyces cerevisiae. In plants, the plasma membrane protein SLAC1 (Slow Anion Channel-Associated 1), which is preferentially expressed in guard cells, encodes a distant homolog of fungal and bacterial dicarboxylate/malic acid transport proteins. SLAC1 is essential in mediating stomatal responses to physiological and stress stimuli. Members of the TDT family exhibit 10 putative transmembrane alpha-helical spanners (TMSs).	2.4507e-98
NZ_CP045571.1\|WP_139112156.1\|1466354_1466729_-\|SWF/SNF-helicase-family-protein	gnl\|CDD\|350180	cd18793, SF2_C_SNF, C-terminal helicase domain of the SNF family helicases. The Sucrose Non-Fermenting (SNF) family includes chromatin-remodeling factors, such as CHD proteins and SMARCA proteins, recombination proteins Rad54, and many others. They are DEAD-like helicases belonging to superfamily (SF)2, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.	5.09451e-07

>NZ_CP045571.1|WP_065973799.1|1457923_1459138_-|ISAzo13-family-transposase
MEADALIAARHQALEGILDERQRRLYAAVEAKVLGHGGVKRVSEATGVARGSIMAGLKELKDPENRLPQGRVRRSGGGRKRLVDRDPDLLVALEGLVDPAARGDPQSPLRWTCKSLKQLARELSEQGHRISHVSVGILLKELGYSLQGNRKTLEGTDHPDRDAQFRYIQEKTQQALDAVQPVISVDTKKKELVGNYKNAGQEWRPQGEPEVVQVHDFVDKELGRANPYGVYDLAQNAGWVSVGTDHDTASFAVATIRRWWLGMGQPLYPDAKELMITADGGGSNGSRVRLWKLELQGLADEFNLPIRVCHFPPGTSKWNKIEHRLFSYISMNWRGRPLVSHEVIVNLIAATTTSKGLKVYAAIDPTPYPKGIKVTNAEFATIQIDRDNFHGEWNYVISPNKKFM
>NZ_CP045571.1|WP_153940574.1|1456207_1457827_+|glucose-6-phosphate-isomerase
MSAVLCNLPAWRRLQEHRQSLEHVTLRQLFQEDPHRAGHFSAEACGIYLDYSKHLLRRETLNLLFDLAHSRDLEARRDAMFAGEKINHTEGRAAFHAALRAPRGMVMRTGGVDVVPEVHQVLEHMARFTQSIHEQSWRGATGQPIRQIVNIGIGGSYLGPEMAWKALRAYRHTDVHLHFVANVDGATLSDVTANLDPAETLFIISSKTFTTLETMTNAHAARHWITSALGEDAVSRHFVAVSTNAEAVKAFGMDTEHMFGFRDWVGGRYSMDSAIGLSTMLGVGVQHFQEMLAGFHAMDMHFQNAPLEQNLPVLLGLMSIWYNNFWGAQTQAILPYAYDLARFPAYLQQLQMESNGKSVDEAGQLLSVDSGPIIWGEPGTDGQHSFYQLIHQGTRLIPCDFIGFCHPLSASAEPHELLMANLIAQAEALAFGKTAEELRAEGVSEAQVPFRTFAGNRPSSVLLVDALSPHSLGTLVALYEHSVFTQGLIWGIDSFDQWGVELGKVLAQRIVSDMQGKTQHPHDGSTSTLLERYLRRRGH
>NZ_CP045571.1|WP_012387019.1|1454729_1455944_+|ISL3-family-transposase
MVPEELFSLALGLVPPWLVDHVTFTVEEKRLDLHINFPKGSRFACSVCGEECPVHDTRDHTWRHMDFFQHEAYLHARVPRVKCQEHGVHQISVPWAREGSRFTLLFEALIMTLVREMPVLTAARMVGETDKLLWRVIDHYVPEARAAVDMANVHAVGVDETSSRHGHDYITLFVDLNARRLLFATPGKDAKTFEKFSADLQAHGGSAEAITDVSMDLSPAFQKGAAEHLPNAEITFDRFHLMKLVNEAVDDVRKGEVLTQPNLKKTRWLWLKNDCNLKMKQKEKLQELLKDQNLKTAQAYQFRLTFQDIFTIKNRHQGATLLKAWLENARTSDLPPIVRVAYTIMNHWDGVLRWFESQITNGILEGFNSLIQSAKAKARGYRTHKNFINMAYLILGKLDLRLPT
>NZ_CP045571.1|WP_153940573.1|1453612_1454509_+|LysR-family-transcriptional-regulator
MVDDEQLLSLLAVAQYGSISAAAEHLNRGQSAISERLRKLTDQVGEPLYTREVNGVKLTPAGASLIPDIERLRRVLRDIDSVIKRRKTLAEGNLNIVSTSLITNYFLIPYLSRFRLEYPHINLHIKSGERYMHDVAAGDVDLFFYEGNSDIPELPDYFDSIPWQDNEIVLVTPLNHSLAQRTDLTFEEIKDYSIIWREPGSGVRNAVEKEFKKRNIILERYIEVADIESVGSLVSANLGVGFMSKKVLTLRSDWKVSTATLETHEMICLNFMAAPSPGRRSRVLDKFLEWIQDPAKTT
>NZ_CP045571.1|WP_153940572.1|1452445_1453306_-|sigma-70-family-RNA-polymerase-sigma-factor
MNIDTTPEVTKTRRNNVNPENKLEAFVSQSSIQTYLKEISCHVLLTKTQEIQLGRLIQQGAHEAWKQLVESNLRLVVQIARRYGQKNSLTLSDLIEEGNLGLMHAAEKFDPDLGYRFSTYATIWIREYIERAIMNQSRMIRLPIPVIKKLRATLNSSSDSEQTKNEAQNHLNERILSLNNAKDADDKTNLGDVIADQGAISIEDQYECKEFENIVHKWVNDLPSPQREIVELFYGINPLGPLNNMQIGTIFGFSAQRASNIRLTAMDELRQMASQLDNSYLNDVSV
>NZ_CP045571.1|WP_153940571.1|1451328_1452402_-|C4-dicarboxylate-ABC-transporter
MKPATENTLNHWLNRTTQNLAPGSFAVVMATGAIALSAKILGFIPLSNVLLWVNIVIYIFLWIVLIMRAYKFPRNLSDDFRDLGRGTGFLTIVAGSAILGSQFVLLDHQAIIGIIFLGVSGILWLLLNYGLFFSFITKINKSSFETEISGTWLLITVAIQSISALLSVLQAQNILPYCSCFNFISFSLWLLGDVFYIVIILLILYRMIFFKLSAQDLMPPYWINMGAASISTLAGALLVSCTKDSLFLHDLIPFIKGFTLLFWTTATWWIPLLFILGWWRFIVHKINFSYDSSYWGMVFPLGMYSLCTLHLEKSFSLSFLFLLAYIFFFIALTAWTVTMLAFLHKTYVNFLQIEYIG
>NZ_CP045571.1|WP_153940570.1|1450897_1451173_-|hypothetical-protein
MLASILSKKARLIFACTLVFLFGNSAAWADKISAPEMVIIHLNNALIATMKLGPHSSFQQRYRKLYGTVSKSFNFTEIARYSLGRSWYKLS
>NZ_CP045571.1|WP_170286704.1|1450407_1450878_+|transposase
MHSTTTLVRIDLLVAAHRDVADGPLSDDRMAQINADYTTILAKGDTIHPIKRRKDGSAHRKQSYPTNLLRRLREYREDVLRFLSDPEVPFTNNIAEQAVRMPKVKQKISGCFRTFDGAAAFCTIRSYLETLRKQGVDLLHALVQSFQGETPQPAMG
>NZ_CP045571.1|WP_153940568.1|1448512_1449544_+|IS110-family-transposase
MQITTYGLDLAKKVMQLHWVDMETGEIHRKQMKRRALLEFFANRQPGIVAMEACGSAHYWGRELRKLGHEVRLVAAQFVRPFVKTNKNDAADAAAIWETVQRPDMRFVAVKSEEQQSVLSLHRIREQLIKVRTMQVNQIRGLLYEFGADLPQGRQKGLKEVPDALADLEESLSPMFLDTVRQQLKRLEQMDKDIADIEKCLALWKKDQEAVTRLMAIPGVGLLTATAIIATVGDIKSFRSGREFAAFLGLVPRQSGTGGKVRLLGISKRGDSYLRKLLTHGARAVVNCQIKNRNLWIDKLLCRRPHNVVVVAQANKMARTIWALLVKNTEYVASHTINAASIS
>NZ_CP045571.1|WP_153940567.1|1448229_1448391_-|hypothetical-protein
MPSITRASRGTDKVYLFIDMMISFDGFSEMGRAQSRRSGVEGIFGAYVKGNIQ
>NZ_CP045571.1|WP_081576759.1|1459730_1460006_+|hypothetical-protein
MAFSVMAHADSSMLVTADGGFYSYAFWKHALVTNTRLLFRLSSVVHPPPRRGIARRVVFQHHQPQSNRMKKQSNGVTGPHKRIRLEGHPRC
>NZ_CP045571.1|WP_153940913.1|1462045_1463371_-|porin
MYHDYKISKNTLIVTAAMLGLSPLAHAANWFKLQGVSPAKAPMFSVSGFIEPSIYAQPGNEDNLEKNHIPNTDLIAPGLSQSTTANILRARIELRGNLNPNISYFFGGEFGDNGFTHVCRRYQPGLIDGHFTFSYIPGARIEAGLIRAPSAEGAMQGFMSNNFVLPSTVIGQLMQQPMYNSNDPYKINQQTNAYLINGQQSLGDNAFRYPGIMAFDWFRNGHWEFTYGTMIGMFGTVAAGNQSSSPIYAARLQEAYIFGGKGPFRSDVQAGIWYQHASPELNDTSYSMNRYGVDVQYLQGYMHQWGRQFRFQYMRGTGWISAASAFSSAPGLPATLTNTQLYPGSQNTANGYMLEGGLFLTKHIEANLRYDYYDRLPNDPAQQRIFRTWAIGLQYHFTPLTKIMAGYYFRTLDVPHQPNPVANSISDAVDNEFAMQAMIAF
>NZ_CP045571.1|WP_139112155.1|1463951_1464335_+|hypothetical-protein
MAETYERFGKTMEIAVNTQGAVVRKMFLTVAMRTRDFVMETRRDAESWVDRIMTVMDQQLQRFEAQTEEELQALQQIAKAVEFVETRVQQLEQALMEVQSKEERLNQAAFPFMKLMAADIMASSAST
>NZ_CP045571.1|WP_065974094.1|1464331_1466311_-|type-IIA-DNA-topoisomerase-subunit-B
MASKNYSADQFTVLKGLEPVRLRPGMYTRTTCPTHIVQELIDNSADEALAGQATQIDVTVCPDGSVIVEDNGRGIPVGIPPGESRPAAELAFTTLHAGGKFDKTDQASAYRFSGGLHGVGVAVTNALSKRVVVDIHTRDPEGSGYGHYRLGFADSAIEAPLVRIENSTSRKHGTRVQVWPDARYFDSNRVNIRELTHLLRSKAILLPGLRVTLSLPEQEPILWQYDAGLSGYLEELLADTETITPIFTQSVYQNDDSHGFAEGEGANWAICWAAQGCPKPETYVNLIPTLDGGTHESGFRAGVFEAVRSFMEHHSLMPAKVKLVQEDVTGKMALVLSARILDPQFQGQTKDKLTSREAYKLMVQTIRDPLELWLNSHPEAGRAIVEQAIQSAQLRSRAAKKVERKKGSGLATLPGKLTDCESTDIQRNELFLVEGDSAGGSAKAARDKEYQALLPLRGKVLNTWEVDADLIFKNQEVHNMAVALGIEPHGVDADPEQVLAGLRYGKIMILSDADVDGSHIQVLILTLFLRHFPALLRRGHVFVVKPPLYRVDTTWRGKARKIYCEAETERDAAIERLRAEGVKESAISVQRFKGLGEMNPDQLWETALCPDTRSLVPLTMTLTEQAFLQERFNLLMGKQSAGERRAWMERDGWTADLDV
>NZ_CP045571.1|WP_139112156.1|1466354_1466729_-|SWF/SNF-helicase-family-protein
MQHRCSVVVFGELDWSSGTHQQVIWRVDREGQQSPVTVFFLVVEDGSDGPIMEILGLKASEAHQIVDPFTGPERTDRDMARFQALVQRYLTRASGAQKNVQKKAGVAPHVTKPEQQDLRKLLDG
>NZ_CP045571.1|WP_153940575.1|1466844_1468551_-|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MITLHTRIRNLTPEQDAALSTYAEHFNHVAHHLVTDMVHEKRTGASFKKDYLRRFALTARQFNAICLSVEGLASNRLENLKNQENMLSDKILALQKLLPKIVLQIQKAVMEQQPVAVIQRLKNRLHQKKRKLANLLERQSQVINEQKRPLGSGLCFGGRKLFHAQHHLQENGYQNHAEWLADWKLARSRQFFVLGSNDEAAGCQGCVARIQSDGTFLLDLRLPGTGEKRVTIGPLQFPYEAEKLRNVVALHAQLSKENLPRITNRSKAGKPYSRIVYPEALSALSWRFQRDKDQKGWRVMVSFHQPAAAVQTHVQAGAIGVDLNADHLAWAELDRFGNPMETGNIPCVTYGKTATQAEALIEASAIALTQRAKQTGKPLVLEKLDFSQKKTQLSEVDGPRYARMLSSLSYRKIHDAIAARAAKDGVEVKTVSPKFTSVLGRINYAARYGLTVHQGAAVVIGRRAFGRFAKNPHTGKNFKEFGLREMPIGRTGRDGRKTITAPDGRGAQVTFSYPAWNEQKHVWTLLGKVSRKMKAALAAQRVAGQSDPPERMVKSARRKPEVLVVAAV
>NZ_CP045571.1|WP_065973872.1|1468551_1468752_-|hypothetical-protein
MKYEIKRMGKKLGGVLSHRMGVVQNRDLVRASPSVGDRHYFVWAALCKTSGRKGDGSGRHSPRNEG
>NZ_CP045571.1|WP_153940577.1|1468947_1469718_-|hypothetical-protein
MAEASRTYGVCRYVSDGTRHQWSLEGIEPHVAIRLKQLFPKIPKQSAGPFLLPADLITAADLDWFMSRYPLRISAADRRRLEVDKTGFVERQDHLESILLPTFKAGAITGLRDGQQLRNYQAQAVEVLRYRKSLLLGDEGGLGKTFVAAAFLCSVPGTLPAAVVCDAHMQIQWLEKVTGFTHLRVHCIKKTSPYALPPADVYVFRISQIMGWADIFATDFFRTVVYDEPQSLRTGASTAMSLPRRCLRNIPSTISG
>NZ_CP045571.1|WP_153940578.1|1469717_1470065_-|hypothetical-protein
MQKIVQIIESLRLDLSDEKRLQSDLETALRKAGLSFAREQALSARDIPDFLLQDGIVIECKLRPAQKMAVFRQLDRYAHHPEVRGIVLATNLSMTLPETIREKPAVMASLGKGWL
>NZ_CP045571.1|WP_051690708.1|1470093_1470540_-|hypothetical-protein
MARRVFVDMDGVIVDFAAYMQSSGLTAAEIKRQPGAYLAMPPIDGALEAVRSVIDLGFEVWIATKPPTGIAFAYADKAAWIFQHLPELERRLIITHDKGLLGDAGDYLCDDRPHRANCANFPGTLLAFVDGFHWPQALAVLRGVKQAE

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Crispr_ID: NZ_CP045571_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045571_4

2189332-2189420

Orphan

Consensus_repeat	Method
CCTGCGAAGGGATTGCTCCCCGCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045571_4

>merge|NZ_CP045571|4|2189332-2189420|CRISPRCasFinder
CCTGCGAAGGGATTGCTCCCCGCAAGGGGCTTGCGGACAGCGGTATCCCCGCAGGGGGCTTGCGCCCTGCTAAGGGATTGCTCCCCGCA

>NZ_CP045571|4|1|2189332-2189420|CRISPRCasFinder
CCTGCGAAGGGATTGCTCCCCGCA	AGGGGCTTGCGGACAGCGGTATCCCCGCAGGGGGCTTGCGC
CCTGCTAAGGGATTGCTCCCCGCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045571.1\|WP_153940788.1\|2195220_2196894_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045571.1\|WP_031568861.1\|2199223_2200207_-\|Flp-pilus-assembly-complex-ATPase-component-TadA	unknown	unknown	gnl\|CDD\|227341
NZ_CP045571.1\|WP_051690420.1\|2196903_2198418_-\|shufflon-system-plasmid-conjugative-transfer-pilus-tip-adhesin-PilV	unknown	unknown	gnl\|CDD\|309860
NZ_CP045571.1\|WP_031568894.1\|2184308_2185304_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045571.1\|WP_065974894.1\|2183587_2184319_-\|conjugal-transfer-protein-TrbJ	unknown	unknown	gnl\|CDD\|131827
NZ_CP045571.1\|WP_065975116.1\|2179168_2179927_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|366760
NZ_CP045571.1\|WP_031568874.1\|2190454_2190907_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045571.1\|WP_031568898.1\|2183290_2183539_-\|EexN-family-lipoprotein	unknown	unknown	gnl\|CDD\|380215
NZ_CP045571.1\|WP_031568871.1\|2191342_2192500_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045571.1\|WP_031568892.1\|2185330_2185672_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045571.1\|WP_153940786.1\|2191075_2191267_+\|HU-family-DNA-binding-protein	unknown	unknown	gnl\|CDD\|178961
NZ_CP045571.1\|WP_077273603.1\|2189499_2190399_-\|P-type-conjugative-transfer-ATPase-TrbB	unknown	unknown	gnl\|CDD\|274297
NZ_CP045571.1\|WP_065980358.1\|2185694_2188193_-\|conjugal-transfer-protein-TrbE	unknown	unknown	gnl\|CDD\|237536
NZ_CP045571.1\|WP_065974895.1\|2181750_2183280_-\|P-type-conjugative-transfer-protein-TrbL	unknown	unknown	gnl\|CDD\|131830
NZ_CP045571.1\|WP_139112214.1\|2188164_2188563_-\|VirB3-family-type-IV-secretion-system-protein	unknown	unknown	gnl\|CDD\|184348
NZ_CP045571.1\|WP_031568880.1\|2189008_2189257_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045571.1\|WP_153940787.1\|2194280_2195228_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|133030
NZ_CP045571.1\|WP_070114524.1\|2179944_2181465_-\|IS21-family-transposase	unknown	unknown	gnl\|CDD\|226950
NZ_CP045571.1\|WP_065973572.1\|2192784_2193999_-\|ISL3-family-transposase	unknown	unknown	gnl\|CDD\|376574
NZ_CP045571.1\|WP_153940789.1\|2198435_2198900_-\|type-IV-pilus-biogenesis-protein-PilM	unknown	unknown	gnl\|CDD\|369356

Protein	Function_ID	Function_description	E-value
NZ_CP045571.1\|WP_031568861.1\|2199223_2200207_-\|Flp-pilus-assembly-complex-ATPase-component-TadA	gnl\|CDD\|227341	COG5008, PilU, Tfp pilus assembly protein, ATPase PilU [Cell motility and secretion / Intracellular trafficking and secretion].	4.44443e-15
NZ_CP045571.1\|WP_051690420.1\|2196903_2198418_-\|shufflon-system-plasmid-conjugative-transfer-pilus-tip-adhesin-PilV	gnl\|CDD\|309860	pfam04917, Shufflon_N, Bacterial shufflon protein, N-terminal constant region. This family represents the high-similarity N-terminal 'constant region' shared by shufflon proteins.	4.87278e-23
NZ_CP045571.1\|WP_153940789.1\|2198435_2198900_-\|type-IV-pilus-biogenesis-protein-PilM	gnl\|CDD\|369356	pfam07419, PilM, PilM. This family contains the bacterial protein PilM (approximately 150 residues long). PilM is an inner membrane protein that has been predicted to function as a component of the pilin transport apparatus and thin-pilus basal body.	3.47095e-07
NZ_CP045571.1\|WP_065974894.1\|2183587_2184319_-\|conjugal-transfer-protein-TrbJ	gnl\|CDD\|131827	TIGR02780, TrbJ_protein, P-type conjugative transfer protein TrbJ. The TrbJ protein is found in the trb locus of Agrobacterium Ti plasmids where it is involved in the type IV secretion system for plasmid conjugative transfer. TrbJ is a homolog of the F-type TraE protein (which is believed to be an inner membrane pore-forming protein, TIGR02761) as well as the vir system VirB5 protein.	1.63427e-14
NZ_CP045571.1\|WP_065975116.1\|2179168_2179927_-\|ATP-binding-protein	gnl\|CDD\|366760	pfam01695, IstB_IS21, IstB-like ATP binding protein. This protein contains an ATP/GTP binding P-loop motif. It is found associated with IS21 family insertion sequences. The function of this protein is unknown, but it may perform a transposase function.	6.60069e-72
NZ_CP045571.1\|WP_031568898.1\|2183290_2183539_-\|EexN-family-lipoprotein	gnl\|CDD\|380215	NF033216, lipo_YgdI_YgdR, YgdI/YgdR family lipoprotein. Members of this family are exclusively lipoproteins of small size, including YgdI and YgdR from E. coli K-12.	0.00202732
NZ_CP045571.1\|WP_153940786.1\|2191075_2191267_+\|HU-family-DNA-binding-protein	gnl\|CDD\|178961	PRK00285, ihfA, integration host factor subunit alpha; Reviewed.	9.59668e-14
NZ_CP045571.1\|WP_077273603.1\|2189499_2190399_-\|P-type-conjugative-transfer-ATPase-TrbB	gnl\|CDD\|274297	TIGR02782, conjugal_transfer_protein, P-type conjugative transfer ATPase TrbB. The TrbB protein is found in the trb locus of Agrobacterium Ti plasmids where it is involved in the type IV secretion system for plasmid conjugative transfer. TrbB is a homolog of the vir system VirB11 ATPase, and the Flp pilus sytem ATPase TadA. [Cellular processes, Conjugation].	1.6417e-129
NZ_CP045571.1\|WP_065980358.1\|2185694_2188193_-\|conjugal-transfer-protein-TrbE	gnl\|CDD\|237536	PRK13873, PRK13873, conjugal transfer ATPase TrbE; Provisional.	0
NZ_CP045571.1\|WP_065974895.1\|2181750_2183280_-\|P-type-conjugative-transfer-protein-TrbL	gnl\|CDD\|131830	TIGR02783, probable_conjugal_transfer_protein_TrbL, P-type conjugative transfer protein TrbL. The TrbL protein is found in the trb locus of Agrobacterium Ti plasmids where it is involved in the type IV secretion system for plasmid conjugative transfer. TrbL is a homolog of the F-type TraG protein (which is believed to be a mating pair stabilization pore-forming protein, pfam07916) as well as the vir system VirB6 protein. [Cellular processes, Conjugation].	1.58539e-32
NZ_CP045571.1\|WP_139112214.1\|2188164_2188563_-\|VirB3-family-type-IV-secretion-system-protein	gnl\|CDD\|184348	PRK13823, PRK13823, conjugal transfer protein TrbD; Provisional.	1.93631e-12
NZ_CP045571.1\|WP_153940787.1\|2194280_2195228_+\|glycosyltransferase	gnl\|CDD\|133030	cd04187, DPM1_like_bac, Bacterial DPM1_like enzymes are related to eukaryotic DPM1. A family of bacterial enzymes related to eukaryotic DPM1; Although the mechanism of eukaryotic enzyme is well studied, the mechanism of the bacterial enzymes is not well understood. The eukaryotic DPM1 is the catalytic subunit of eukaryotic Dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. The enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. This protein family belongs to Glycosyltransferase 2 superfamily.	3.11529e-90
NZ_CP045571.1\|WP_070114524.1\|2179944_2181465_-\|IS21-family-transposase	gnl\|CDD\|226950	COG4584, COG4584, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.45771e-40
NZ_CP045571.1\|WP_065973572.1\|2192784_2193999_-\|ISL3-family-transposase	gnl\|CDD\|376574	pfam01610, DDE_Tnp_ISL3, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS1165.	1.99873e-93

>NZ_CP045571.1|WP_031568880.1|2189008_2189257_-|hypothetical-protein
MRLSLPTETASSERQALQWICRRLSLRLDFQGPDYALYGAGVPFGKPVPALELLRDLAVIPYIQGTMTVRLHSVKVHNAPLR
>NZ_CP045571.1|WP_139112214.1|2188164_2188563_-|VirB3-family-type-IV-secretion-system-protein
MSQETRSTRLYQSMVRPHLLMGGERSATLLNGGAAITIYFLTLSIPGIIAGVLTFTAVQTVLRILARQDPQMISIVFRARKWQDYYPDAPSLDAPVREIPVEKSQQASIWNQILSRFAKKDRKHAEPAGIPE
>NZ_CP045571.1|WP_065980358.1|2185694_2188193_-|conjugal-transfer-protein-TrbE
MLNLREFRSKNLSLPDLLNPAILAGRVLVLNRPCAVLLTKDGAFLSAVRFFGQDLESLSADDINRLSAVLNAAVTRLGTGWTVQTTAIRESADGYVPEDQCFFPDPVSMLIDNERRRAFEREGRRFQSRYYFVFTWNTPPESEVSAGHLFVESRKGIVSDSFDTLLKKFEDSLNMALGILSRQYAITPLDDTGLLTHYHECLTGKSHPVHAPTIPAYLDVLLGHHEFVAGLEPALDGESISVLTFLGYPDLTRPEMLEHLHNLPFPLRYTTRFILLDSVDSKKLVAKVREKWASSKYTLRDYISGAMSHGQMRADRQDRFKAGMESETALVDADISSGAILMGFFTATVILRHRDAKTLEERSRMVMNLLSTVGFVPKRETVNAVEAFFGSLPGHTWENVRRAPIHSLNFADLSPKTGVWAGDPECPSPLIRIGSQPAPCLVLAQTSGSTPFRFNLHVGDVGHSLLAGPTGAGKSSLLALLAAQWLRYQNARVIAFDKGRSLFALTEAVGGQHYDLGGEYSGLSFAPLERVDAEMDRVFAKDWLEALAIVQGVTMTVRERKTINDAVDGLARESGRSLTDVMHLLQDEHLKAAVSVYTGTGKYGDILDARQDGLDLSSRFLTFEMDSLPQGETGKQLVVPLLLYLFYRIEKMLDGSPTLIVMDEAWTLIDNPQFLAKIREWLKVLRKKNAVVVFATQSLADLQGSPLLPVLMESCPTKVFLPNREAGSQQLKPMYHNFGLSDRQIELLQSAIPKQDYYIHSPLGHRLVSFAMGPITLAFCGVSDPKAVKRVAELRETLGRAWPVAWLRERLPAPVLREWGDVIAFIERSFHG
>NZ_CP045571.1|WP_031568892.1|2185330_2185672_-|hypothetical-protein
MKSIQRISAFVVLLSVSTLAFAGGPVSNFPVQEQLQQEVRMAQAVLNDVHSGGNRHQLMQRVQALNFAVQNTASQMRVTPPAASHMVRLHATRRELVKHVEVVRNWIVAQQKA
>NZ_CP045571.1|WP_031568894.1|2184308_2185304_-|hypothetical-protein
MMLTCIPVLSVAGTPLQGASPLQGMQSDAAAIQSMAQNWTTLENAASGYAALAPYAAQEWAGPGPVVSTPMGGEEQCHNIHWDTVTNQLVTGGLNIFGDAEAEAYAIQTITADFQTQLADYEVQQAKVGNMAIVDQINAQKGPMNASLNTLMSLLSTTGDQVAAALSPGTTLHPLPIQHWQAGVGNVPDLSAVQYIAGLNDGAPIGWAVEPVRGLARLIDVCPTGTGNVPMYNLSGPVNSNVQQMLADSPSMAQVVQSVEGGSTYSVPGPFSGSAGIVPVDGFGDDTRMQLVKALASDMQPLAQYMQPLRQPLTLYSQQVQQIMAEVQHAN
>NZ_CP045571.1|WP_065974894.1|2183587_2184319_-|conjugal-transfer-protein-TrbJ
MQTNHKKIFLAIALMLSPVSAFAGTLTGGATMPEQIVQEVTLIQSKVTQSEQLVNMIQRYENMIQNMVTLPQTMLNQIMQPVDQLYGVVQQAEALSTAGANIANQFQNLHATFNPQITAEYTQQYESITEGLNKAIDTALKSANLNPNEFQTQAQAQQAVDKAMQNPNSRNAILQAATEVGQATNSAMVQLQQTTQQYQTMQAAWRKKQLMQQEEQKEVNQKMNNDLNGTGQTPTYHLPSFSW
>NZ_CP045571.1|WP_031568898.1|2183290_2183539_-|EexN-family-lipoprotein
MHIWKLFVLCLAVFALAGCSSSTIEKVKVHSEAYYVKHPKALKRANAWCNLKHLSRSQATDCENAQAAAIDKNSPHLPHFSW
>NZ_CP045571.1|WP_065974895.1|2181750_2183280_-|P-type-conjugative-transfer-protein-TrbL
MRGRTGNQKIPAIALIVGVLLLFAALPADAATGATSGILSAFSQVVTGWYGKILIVSEEIFFTLFGIDFVYLVAQWMIGGKDVHEILTSFVKKLITIGFWYTLLLHSQQFLHWIYGGFEQTGVEAGGAVNVTASSLLGEMMKIWTELLQGPYDAKSHGFLYDISHVGSIMISGLLGDLLGLFTALVMLFIVVYMVIEFFTVQLEAMLVGSIGAILLGFSGSRWTVQHADGFIKYALSVGVRLLVLTLWMGFITKEIPQSIELLMKNSGLGLESGTHLAGLFELYGEILVFFLLVGWLTKKLPGIAASVLSGSSSLGGGELMGAAVGGAALAAGGAAVLATGGAALAAGGASGAMTASEAVAASGGVGGAGEMGAAAGNAAETAGGGAGGMGNGLADSGMADTGNASSNSPASPAPVTEAETESIRRQLARMKSSDRTASSTGPASGTETADAMRGEAQPKPEQKPLHERAMEWIDSREKDAHFVEQHVVPGEHETVSVSAEGNKLSHSE
>NZ_CP045571.1|WP_070114524.1|2179944_2181465_-|IS21-family-transposase
MKAIIEILRLHAAGCSQRQIARACGLSKGAVGKYLQRATEARIGWPLSEGLTVVEVEQRLNPRRQPLPASRPVPPDLAQIHTELRRKGVTLQLLWEEYVATHPDERTYQYAQFCVHYRSWKARLKTSMRQQHVAGEKLFIDYAGPTVAVVDPGTGEIRQAQIFVAVLGASSYTYCEATWSQSLPDFLGSHVRAFRYFGGVPTLLVPDNLKAAVTKASRYEPEINRSYRDLATHYGTVVLPTRPYKPQDKAKVEVGVQVVERWILARLRHFQFFSLMELNREIRRLLEDLNQRPFKRLPGSRQSVFESLDRPALQPLPAQDYVYALWKSAKVSIDSHVAYQGHFYSVPYRLVSVRVDLRVSARTVEIFHQQQRVASHPRQTLQGRYSTVPEHLPKAYQQHREWSPGRLLNWALSIGPATRDVVRWQLARRAHPEQGYRSCLGLLSYSRRYGKERLDAACARALKIGSPTTRSIQSILKQGMDQVQESPSPTTPLPTHDNIRGPHYYQ
>NZ_CP045571.1|WP_065975116.1|2179168_2179927_-|ATP-binding-protein
MLYQPTLHTLRQLNLTAMAEALEEQSLLPQVQDLPFEERLGLLLDRELSARDQRRLTRLLKLAHLKHNACVEDIDYRASRGLERARMLSLIQNTWIRQGQNLLITGATGTGKTWLACALGQQACRQGLSVRYLRLPRLFEELQTRHGDGSFGRYLNTLAKVDLLILDDWGLAPMRGEAVRDLLEILDDRVNQKATLITSQLPVNHWHDYLGEPTVADAVLDRLLHSAHRLELKGESLRRHRDPGTAPKVDPS
>NZ_CP045571.1|WP_077273603.1|2189499_2190399_-|P-type-conjugative-transfer-ATPase-TrbB
MRRILGADICAVFGDPAAVEIMLNDDGRVLVERHGQGITHLTDLSASKALNLLALMADFRGTTVTRDKPIVEGAMPDEFLRARFAGAIPPLMPRPTFSIRLPARKIYTLEDYRNNAIITGEQYDKIIEAVENRKNILVSGGTGSGKTTLLNAVSDTIACRAGLDQRIVIIEDTREIVCNAPNTVQMLTDADTDIDMTRLLKLTLRYRPDRIFVGEVRDGAALALLKAWNTGHPGGLATLHANSTQAALTRLDQLCQEAGVPSQMPLIHEAVDVIIQIARDASVPAGRRITDILFMDKQD
>NZ_CP045571.1|WP_031568874.1|2190454_2190907_-|hypothetical-protein
MSATGTVKLTGRYGDRIEQEARERSVSKAALIADYAMRGIETAEQAEGSPMDGFERRIAATMLAVRGDVEAVQAELDTVAAMLDLFVKLMLIHLPEPVLDEAEAVQSSALTRYERFLKQVADAGFDGDRPRALKKIAELLQKKLEPVQNG
>NZ_CP045571.1|WP_153940786.1|2191075_2191267_+|HU-family-DNA-binding-protein
MIGQRRNIHHAQTGIGKESKRLVESFFNTRPNPKTGEMVPITARRVVTYRASHLLKEACLVVG
>NZ_CP045571.1|WP_031568871.1|2191342_2192500_-|hypothetical-protein
MIHGENDDLGTEDGARPSLGSDDLFKMKNFSVRIPNYLLDSIRRLVSNKQTASDLVRLSMEKTFGLDGVNTMKEYEELQRDNRASLERLVSKVKTSSQFSRAEIMYVANECHSAYSHKLSKYKRIKNFSIVSNLLAFNEMIKLRDATKPMTEEANRLDHYYHGCLGRQGRPFESSIDKHVHYIVNEIFGADYVHPTSAEMAARCFEVASRDEPELSICKLNDAIRPFIGNMILFLLRVYYIKNGSTAVKIEGDFAEPKMIQDVINESFWITPMLSENGLSCAVELRGRNVVFSLNNTPEIDDFIAALMSARQDGVMEAVVGRFHCQYTINSASPQMSTFFISVGGCRVFMEKEEYDGLCDLFKTFMENEDVSNARKNLMWIYGDI
>NZ_CP045571.1|WP_065973572.1|2192784_2193999_-|ISL3-family-transposase
MVPEELFSLALGLVPPWLVDDVTFQVEEKRLDLHINFPKGSRFACPVCGEECPVHDTREHTWRHMDFFQHEAYLHARVPRVMCPEHGVHQIPVPWAREGSRFTLLFEALIMTLVREMPVLTVARLIGETDTLLWRVIDHYVPEARTRVDMAHVHAVGVDETSSRRGHDYITLFVDLEARRLLFATPGKDVSTFARFATDLEAHGGSAEAVTDVSMDLSPAFQKGAKEHLPNAQVTFDRFHLMKLVNEAVDAVRRSEAFTQPDLKKTRWLWLKNERKLKVKQKEKLQALLKDQNLKTAQAYQFRLTFQDIFTIKNRHQGATLLKAWLENAKTSDLPPIVKVAYTIMNHWDGVLHWFESQITNGILEGFNSLIQSAKAKARGYRTHKNFINMAYLILGKLDLRLPT
>NZ_CP045571.1|WP_153940787.1|2194280_2195228_+|glycosyltransferase
MTVSIIVPCHNESGNLKILYERVSGIMDACGEPWGMVCVNDGSIDDTLLQLIELHQQDSRIQVIDLSRNFGKEAALTAGLDAARGDAAIPLDADLQDPPELIPELLAQWRDGYDVVNAVRLSREGESWLKRASAHFFYRVINRMSVVDIPADTGDFRLLSRPVLDALQSLQERRRFMKGLFAWVGFRSTNVYYHRAPRHSGKTTWNYWKLWNFAVEGITSFSQVPLQLAAYLGFIVSGLSFIYALWLIISTLVYGNPVKGYPSMMVTLLFLGGVQLMALGVIGEYLGRIYEESKHRPVYLVRKVWGKIRDRERND
>NZ_CP045571.1|WP_153940788.1|2195220_2196894_+|hypothetical-protein
MIKHWLMWGLFAVLSVAALISSLGTAFQTLPLNPDMAEMALIYQGIVHHGWRFPFTWRFNQDNQFLSLLPFALIFYALVGVSGASIVIQGWLIFVVNAMLSGLVVKTVTRSWMWGYLAWLIALLAGPMAIGQPGILAYPVSHNAVWMFGLIGIIALLRYIIDKPRWAFPTMLVCVFTGTVSDPWFQAAYTLPIIFLLWKAPALFSRDKSDFRIAIKWIVAAYVVGRITYFIFADFNIFSQQSISFASPSIMLKHLILLTKGIGTYLCLYPLPTNFISLVVWFIFIFSVLVVFCFAIIYRKLLPASFIIVILFAFYSSALMSILFVVTNFATGGWAIEYLINIFYLFILSLLAIAYVFESMNFSARIFTRASVIAYLVLSMTLIVNGDFRFSPNWGETKKVVYFLVKNHLYFGYGSYFGAQSPLFALASDGAITGRHMGSNMGLPIIQMGNGDKGFWYSDPSKETTPQFIIFSKADSELISITKKYIGPPNRVIYFLNYTIFIYDRNLLPHLLANRWLSNNRWRQMNIERNVKGINKVCRSLNINPLPIEHAYIEFAH
>NZ_CP045571.1|WP_051690420.1|2196903_2198418_-|shufflon-system-plasmid-conjugative-transfer-pilus-tip-adhesin-PilV
MNPITVLFAVIISALAVPAVYMVMSSQQQQELSTAAAIQMARVEKAAEAYITANAGAIESVATGSSPAVITVPMLESTGYLPNGFTSVNPFGQTWEVQVLQPTSGNLQALVVSYGGNTVKAKVAGQVAQIAGASGGVIGGGSGEYAVPGCTGGEACGSYNGWSVTTSGYQNIQPGHFAALLAYSNGQLQSDYLYRVAVPGQPQLNTMQTNLNMGTNSVNNADEVNAQSETLAAGDPNGQYGALQIGNNYYYGDSSNAAVRTPGGFYVQNQNGSEPASIDEVDNVNASGNITTPATVQGGYVNSTGDVNAQSALTVDGGNAWWANNAGNSSQAGSASVGGVVNANGGVGSGNYFSTYDGAWWSNSSGDSSQSGNLYAGGQIHAGYDAWLGTANGTANQGWGCSDYGEIAASGSGNGQALMCNGSSWQAMGSMTGYNQVGFETIPGNGSSNFGIWEFCSITGHQGQGADELVPVGGPYVVGNHYAWDWSGGGSGTNNTPVTCWNNN
>NZ_CP045571.1|WP_153940789.1|2198435_2198900_-|type-IV-pilus-biogenesis-protein-PilM
MLALIYPFLLLGLLAFYAGNSIITSQSINGSPTSASVPGDAAFVALAHAALAFSEQNQGYSGNITASQLAPYMDGYQFPSQWSASESGGQLIAWTNSLPADGLTALSGETGGDCAYGKNNNGYVSSLCVGTIPQPTPNGIPNNAVVYWIDSPTN
>NZ_CP045571.1|WP_031568861.1|2199223_2200207_-|Flp-pilus-assembly-complex-ATPase-component-TadA
MGLSDLAFADLAVEQDPAASRYKRFSDDLRLVSVPETYWGELQALRNQMEAHNSHRFRMVFGGMNLRVQKRDTPYGSVFIARRIASILRKLDDIGLPIPLVQTLRDARMRSGLLLFAGGPGMGKTTLGCALLMDRLERIGGFTWTAENPVEYDLQGSRGNGQCYQEEIDDDTEVQRVFMDTLRSGADTFYIGEIREQSAAKTAGLAAASGMLVISTLHADNPQQAILKMGMLSGFDGLAQCLRGVVTLRIDKEPAGGAMPGGGMPGGGVANGKSPQSILHVQSFFVEDEPTRMKIRDGNMAAINQDIEAQKNRSMSMGRIYGSAGGR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

104273 : 116622

Bacillus_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_153940356.1\|104273_106223_-	diguanylate cyclase	G3MA91	Bacillus_virus	9.8e-18	33.1
WP_024894514.1\|107165_107696_-	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	3.6e-23	38.0
WP_010640796.1\|107718_108006_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_024894515.1\|108021_108984_-	DnaJ domain-containing protein	A0A2L0UZR4	Agrobacterium_phage	2.1e-21	29.8
WP_031575890.1\|109100_111230_+	UvrD-helicase domain-containing protein	A7KV33	Bacillus_phage	2.0e-117	37.6
WP_024894517.1\|111309_111750_+	ComEA family DNA-binding protein	NA	NA	NA	NA
WP_024894518.1\|111766_112699_-	homoserine kinase	NA	NA	NA	NA
WP_024894519.1\|112726_113089_-	DUF2782 domain-containing protein	NA	NA	NA	NA
WP_024894520.1\|113106_113826_-	TIGR00730 family Rossman fold protein	A0A1D8KU27	Synechococcus_phage	1.1e-19	35.1
WP_024894521.1\|113895_116622_+	DNA polymerase I	A0A142F1Q9	Bacillus_phage	8.5e-68	31.4

DBSCAN-SWA_2

356931 : 365254

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_031573636.1\|356931_358176_+	serine hydroxymethyltransferase	A0A219Y950	Aeromonas_phage	1.4e-97	55.5
WP_035210942.1\|358181_358685_+	transcriptional repressor NrdR	NA	NA	NA	NA
WP_081577438.1\|358674_359775_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	1.1e-39	34.8
WP_010641384.1\|359778_360435_+	riboflavin synthase	A0A2I2L4R9	Orpheovirus	4.6e-20	39.0
WP_031573642.1\|360431_361553_+	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	1.0e-51	37.4
WP_010641389.1\|361562_362027_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	9.4e-36	53.0
WP_031573646.1\|362033_362480_+	transcription antitermination factor NusB	NA	NA	NA	NA
WP_031573649.1\|362592_363168_+	sel1 repeat family protein	NA	NA	NA	NA
WP_024894705.1\|363190_363535_-	LapA family protein	NA	NA	NA	NA
WP_024894706.1\|363571_365254_-	ubiquinone biosynthesis regulatory protein kinase UbiB	A0A2N9QVT9	Dishui_lake_phycodnavirus	9.0e-36	27.5

DBSCAN-SWA_3

480769 : 486871

Escherichia_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_031576046.1\|480769_481276_+	peptide deformylase	E3SLL2	Synechococcus_phage	4.1e-16	39.5
WP_031572551.1\|481549_482686_-	dTDP-glucose 4,6-dehydratase	A0A291LAD7	Escherichia_phage	4.9e-78	45.1
WP_080707819.1\|482699_483569_-	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	8.8e-35	38.3
WP_010641579.1\|483632_484139_-	hypothetical protein	NA	NA	NA	NA
WP_010641580.1\|484138_484477_-	DUF3579 domain-containing protein	NA	NA	NA	NA
WP_031572536.1\|484540_485089_-	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	3.9e-49	55.5
WP_010641583.1\|485085_485970_-	glucose-1-phosphate thymidylyltransferase RfbA	K7QKA7	Escherichia_phage	7.0e-88	55.0
WP_010641585.1\|485959_486871_-	UTP--glucose-1-phosphate uridylyltransferase GalU	A0A127AW70	Bacillus_phage	4.1e-67	47.6

DBSCAN-SWA_4

617860 : 674560

Acidithiobacillus_phage(20.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_153940414.1\|617860_618910_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_153940902.1\|622789_624115_+	diguanylate cyclase	NA	NA	NA	NA
WP_065975116.1\|624072_624831_-	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	2.2e-74	59.2
WP_070114524.1\|624848_626369_-\|transposase	IS21 family transposase	K4I413	Acidithiobacillus_phage	1.5e-146	53.3
WP_153940416.1\|626418_627360_+	EAL domain-containing protein	NA	NA	NA	NA
WP_153940417.1\|627956_629201_-	ParB/RepB/Spo0J family partition protein	NA	NA	NA	NA
WP_153940418.1\|629202_629973_-	AAA family ATPase	NA	NA	NA	NA
WP_031575425.1\|629975_630371_-	hypothetical protein	NA	NA	NA	NA
WP_153940419.1\|630465_631119_-	S26 family signal peptidase	NA	NA	NA	NA
WP_080707873.1\|631090_631303_-	hypothetical protein	NA	NA	NA	NA
WP_153940420.1\|631265_631559_-	hypothetical protein	NA	NA	NA	NA
WP_153940421.1\|631606_632977_-	conjugal transfer protein TraB	NA	NA	NA	NA
WP_153940422.1\|632973_633567_-	hypothetical protein	NA	NA	NA	NA
WP_075324056.1\|634050_634347_+	putative addiction module antidote protein	A0A141GEX5	Brucella_phage	9.3e-13	47.3
WP_031575411.1\|634808_635492_-	hypothetical protein	NA	NA	NA	NA
WP_153940423.1\|636110_638162_-	DNA topoisomerase 3	A0A1X9I6W8	Streptococcus_phage	3.0e-33	30.1
WP_153940424.1\|638684_639605_+	hypothetical protein	NA	NA	NA	NA
WP_170286686.1\|639676_640540_+	RNA-directed DNA polymerase	Q7M2A9	Enterobacteria_phage	1.3e-27	29.2
WP_031575399.1\|643193_643499_-	hypothetical protein	NA	NA	NA	NA
WP_170286687.1\|643728_643902_+	hypothetical protein	NA	NA	NA	NA
WP_153940426.1\|643888_644419_+	hypothetical protein	NA	NA	NA	NA
WP_140390914.1\|644700_645189_+	DUF2442 domain-containing protein	NA	NA	NA	NA
WP_010641842.1\|645216_645471_-	Txe/YoeB family addiction module toxin	NA	NA	NA	NA
WP_010641843.1\|645467_645719_-	type II toxin-antitoxin system prevent-host-death family antitoxin	NA	NA	NA	NA
WP_081576824.1\|645861_647922_-	transglycosylase domain-containing protein	NA	NA	NA	NA
WP_153940903.1\|652159_653125_+\|transposase	IS110 family transposase	A0A1S7J231	Thermus_phage	1.0e-23	31.2
WP_153940427.1\|653091_653367_-	hypothetical protein	NA	NA	NA	NA
WP_153940376.1\|653483_654746_+\|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	3.4e-88	44.9
WP_010641848.1\|656323_656596_+	hypothetical protein	NA	NA	NA	NA
WP_081576813.1\|656634_657927_-	Y-family DNA polymerase	A0A1W6JNT0	Morganella_phage	1.1e-70	38.7
WP_081576814.1\|657929_658400_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	5.1e-29	51.2
WP_081576815.1\|658488_660075_-	APC family permease	NA	NA	NA	NA
WP_140390916.1\|661413_661662_-	hypothetical protein	NA	NA	NA	NA
WP_081576817.1\|662110_663673_+	APC family permease	NA	NA	NA	NA
WP_153940428.1\|663951_664638_+	DUF1275 family protein	NA	NA	NA	NA
WP_081576825.1\|665005_665905_-	GTP-binding protein	NA	NA	NA	NA
WP_081576826.1\|665910_666165_-	hypothetical protein	NA	NA	NA	NA
WP_081576818.1\|668049_668907_-	DUF2236 domain-containing protein	NA	NA	NA	NA
WP_081576819.1\|669329_669578_+	hypothetical protein	NA	NA	NA	NA
WP_153940429.1\|669633_669780_+	hypothetical protein	NA	NA	NA	NA
WP_153940366.1\|669839_671102_+\|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	2.4e-89	45.4
WP_153940430.1\|671177_671558_+	hypothetical protein	NA	NA	NA	NA
WP_081576820.1\|671574_672309_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_081577182.1\|672771_673248_-	cupin domain-containing protein	NA	NA	NA	NA
WP_065972780.1\|673474_674560_-\|transposase	IS630 family transposase	NA	NA	NA	NA

DBSCAN-SWA_5

798695 : 854989

Mycobacterium_phage(50.0%)

tRNA,transposase,integrase

attL 833214:833273|attR 845395:846809

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010636853.1\|798695_798983_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	NA	NA	NA	NA
WP_024894153.1\|798995_800468_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA	NA	NA	NA
WP_081577189.1\|800470_801904_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB	NA	NA	NA	NA
WP_024894155.1\|802000_802555_-	SCP2 sterol-binding domain-containing protein	NA	NA	NA	NA
WP_024894156.1\|802888_803377_-	glutathione peroxidase	A0A1S7DLQ4	Molluscum_contagiosum_virus	1.5e-15	40.7
WP_139110705.1\|803428_804091_-	PilZ domain-containing protein	NA	NA	NA	NA
WP_031569193.1\|804496_805465_+	ubiquinol oxidase subunit II	NA	NA	NA	NA
WP_031569195.1\|805494_807645_+	cbb3-type cytochrome c oxidase subunit I	NA	NA	NA	NA
WP_010643012.1\|807714_808353_+	cytochrome c oxidase subunit 3	NA	NA	NA	NA
WP_010643010.1\|808349_808715_+	hypothetical protein	NA	NA	NA	NA
WP_153940459.1\|808741_809677_+	cytochrome C oxidase assembly protein	NA	NA	NA	NA
WP_153940460.1\|809698_810667_+	protoheme IX farnesyltransferase	NA	NA	NA	NA
WP_010636841.1\|810681_811107_+	Rrf2 family transcriptional regulator	NA	NA	NA	NA
WP_010636839.1\|811497_812010_+	hypothetical protein	NA	NA	NA	NA
WP_139110688.1\|812054_812549_+	thiosulfate oxidation carrier protein SoxY	NA	NA	NA	NA
WP_139110687.1\|812592_812925_+	thiosulfate oxidation carrier complex protein SoxZ	NA	NA	NA	NA
WP_035209742.1\|812990_814700_+	thiosulfohydrolase SoxB	NA	NA	NA	NA
WP_024895115.1\|814742_815474_+	hypothetical protein	NA	NA	NA	NA
WP_031569888.1\|815484_817299_+	cytochrome c biogenesis protein ResB	NA	NA	NA	NA
WP_010636830.1\|817346_817730_+	sulfur oxidation c-type cytochrome SoxX	NA	NA	NA	NA
WP_031569886.1\|817758_818622_+	sulfur oxidation c-type cytochrome SoxA	NA	NA	NA	NA
WP_024895119.1\|818690_819872_+	c-type cytochrome biogenesis protein CcsB	NA	NA	NA	NA
WP_010636824.1\|820166_820784_+	hypothetical protein	NA	NA	NA	NA
WP_010636822.1\|820902_821328_+	Rrf2 family transcriptional regulator	NA	NA	NA	NA
WP_031572923.1\|821558_823106_-	fibronectin/fibrinogen-binding protein	M1H1U8	Paramecium_bursaria_Chlorella_virus	5.4e-11	40.2
WP_031572922.1\|823117_824773_-	sulfate adenylyltransferase	A0A2P1ELS9	Moumouvirus	2.4e-97	36.0
WP_031572919.1\|824783_825353_-	adenine phosphoribosyltransferase	NA	NA	NA	NA
WP_031572916.1\|825418_826636_-	hypothetical protein	NA	NA	NA	NA
WP_031572913.1\|826632_830025_-	hypothetical protein	NA	NA	NA	NA
WP_051690640.1\|830017_830689_-	DUF4194 domain-containing protein	NA	NA	NA	NA
WP_031572908.1\|830708_832172_-	DUF3375 domain-containing protein	NA	NA	NA	NA
WP_031572906.1\|832214_832646_-	PIN domain-containing protein	NA	NA	NA	NA
WP_010636975.1\|832649_832886_-	type II toxin-antitoxin system PrlF family antitoxin	NA	NA	NA	NA
833214:833273	attL	NA	NA	NA	NA
WP_153940366.1\|833256_834519_-\|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	2.4e-89	45.4
WP_153940461.1\|836077_837340_-\|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	4.5e-88	44.9
WP_081577140.1\|837473_839570_-	hypothetical protein	NA	NA	NA	NA
WP_153940462.1\|839901_841158_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_153940463.1\|841380_841620_-	DUF4113 domain-containing protein	NA	NA	NA	NA
WP_153940464.1\|841845_843579_-	recombinase family protein	A0A2K9V2Y5	Faecalibacterium_phage	6.7e-18	26.5
WP_153940366.1\|844148_845411_+\|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	2.4e-89	45.4
WP_153940465.1\|845470_845902_+	hypothetical protein	NA	NA	NA	NA
WP_170286693.1\|845991_847674_-	recombinase family protein	A0A142LP20	Marinitoga_camini_virus	1.2e-11	23.6
845395:846809	attR	NA	NA	NA	NA
WP_065975079.1\|847953_848496_+	hypothetical protein	NA	NA	NA	NA
WP_065975078.1\|848612_849341_-	hypothetical protein	NA	NA	NA	NA
WP_153940467.1\|849777_851040_-\|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	5.3e-89	45.2
WP_081577540.1\|851422_852262_+	hypothetical protein	NA	NA	NA	NA
WP_170286694.1\|852269_853709_+	hypothetical protein	NA	NA	NA	NA
WP_153940376.1\|853726_854989_-\|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	3.4e-88	44.9

DBSCAN-SWA_6

968204 : 1025256

Streptococcus_phage(15.38%)

tRNA,transposase,integrase,protease

attL 973968:973984|attR 1022923:1022939

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_051690612.1\|968204_969659_+\|protease	DegQ family serine endoprotease	A0A1B1IT49	uncultured_Mediterranean_phage	1.9e-18	25.7
WP_031572326.1\|969762_971565_+	elongation factor 4	E4ZFJ7	Streptococcus_phage	9.4e-23	25.0
WP_024893897.1\|971584_972376_+	signal peptidase I	NA	NA	NA	NA
WP_031572325.1\|972461_972878_+	DUF4845 domain-containing protein	NA	NA	NA	NA
WP_010640229.1\|973205_973886_+	ribonuclease III	E5ERU0	Ostreococcus_lucimarinus_virus	4.0e-19	31.3
WP_024893895.1\|973878_974793_+	GTPase Era	NA	NA	NA	NA
973968:973984	attL	NA	NA	NA	NA
WP_010640233.1\|974782_975523_+	DNA repair protein RecO	NA	NA	NA	NA
WP_024893893.1\|975542_976268_+	pyridoxine 5'-phosphate synthase	NA	NA	NA	NA
WP_031572324.1\|976264_976654_+	holo-ACP synthase	NA	NA	NA	NA
WP_031572323.1\|976657_977980_+	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	3.5e-75	37.6
WP_031572322.1\|977981_978923_+	D-glycero-beta-D-manno-heptose-7-phosphate kinase	A0A2H4N7X4	Lake_Baikal_phage	4.0e-17	28.1
WP_024893890.1\|978919_979705_+\|tRNA	tRNA 2-thiocytidine biosynthesis protein TtcA	A0A0U2S5Z2	Escherichia_phage	4.1e-39	36.8
WP_010640244.1\|979697_980540_+	Hsp33 family molecular chaperone HslO	NA	NA	NA	NA
WP_031572321.1\|981180_982329_+	Fic family protein	D7RWK9	Brochothrix_phage	3.5e-31	28.2
WP_031572320.1\|982512_982749_+	hypothetical protein	NA	NA	NA	NA
WP_031572319.1\|982961_983222_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_031572318.1\|983855_984317_+	DUF177 domain-containing protein	NA	NA	NA	NA
WP_010639780.1\|984331_984517_+	50S ribosomal protein L32	NA	NA	NA	NA
WP_010639782.1\|984554_985580_+	phosphate acyltransferase PlsX	NA	NA	NA	NA
WP_031572317.1\|985576_986521_+	ketoacyl-ACP synthase III	NA	NA	NA	NA
WP_031572316.1\|986575_987511_+	ACP S-malonyltransferase	NA	NA	NA	NA
WP_031572315.1\|987510_988260_+	3-oxoacyl-ACP reductase FabG	NA	NA	NA	NA
WP_031572314.1\|988344_988593_+	acyl carrier protein	A0A1S5R3K8	Pseudomonas_phage	3.2e-06	41.8
WP_031572313.1\|988631_989873_+	beta-ketoacyl-ACP synthase II	NA	NA	NA	NA
WP_031572312.1\|989902_990733_+	aminodeoxychorismate lyase	NA	NA	NA	NA
WP_031572311.1\|990732_991740_+	endolytic transglycosylase MltG	NA	NA	NA	NA
WP_031572310.1\|991736_992387_+	dTMP kinase	M1PSC7	Streptococcus_phage	4.4e-31	40.5
WP_031572309.1\|992383_993385_+	DNA polymerase III subunit delta'	NA	NA	NA	NA
WP_081577520.1\|993368_993731_+	PilZ domain-containing protein	NA	NA	NA	NA
WP_153940443.1\|995723_996809_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_153940476.1\|996721_997984_+	phospholipase	NA	NA	NA	NA
WP_024894748.1\|998569_999016_-	Hsp20/alpha crystallin family protein	A0A1B2LRT2	Wolbachia_phage	5.5e-17	35.8
WP_080707857.1\|999643_1000057_-	sel1 repeat family protein	NA	NA	NA	NA
WP_051690717.1\|1000232_1000799_-	hypothetical protein	NA	NA	NA	NA
WP_081576651.1\|1002569_1003685_+	cellulase family glycosylhydrolase	NA	NA	NA	NA
WP_153940477.1\|1003738_1003969_-	hypothetical protein	NA	NA	NA	NA
WP_153940478.1\|1004261_1004933_-	hypothetical protein	NA	NA	NA	NA
WP_077218551.1\|1005469_1005718_+	hypothetical protein	NA	NA	NA	NA
WP_010636705.1\|1005833_1006082_-	hypothetical protein	NA	NA	NA	NA
WP_153940479.1\|1007341_1007773_+\|transposase	IS200/IS605 family transposase	G9CU69	Helicobacter_phage	8.2e-10	31.7
WP_031573976.1\|1007944_1009051_-	hypothetical protein	NA	NA	NA	NA
WP_010636697.1\|1009206_1009734_-	DedA family protein	NA	NA	NA	NA
WP_031573973.1\|1009733_1010324_-	cytochrome b/b6 domain-containing protein	NA	NA	NA	NA
WP_010636694.1\|1010361_1010961_-	hypothetical protein	NA	NA	NA	NA
WP_051690691.1\|1011042_1011309_-	hypothetical protein	NA	NA	NA	NA
WP_031573965.1\|1011305_1011974_-	hypothetical protein	NA	NA	NA	NA
WP_031573962.1\|1011973_1013521_-	glucan biosynthesis protein	NA	NA	NA	NA
WP_153940443.1\|1013976_1015062_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_153940480.1\|1016259_1016397_+	hypothetical protein	NA	NA	NA	NA
WP_035210302.1\|1017956_1018313_+	AlpA family phage regulatory protein	NA	NA	NA	NA
WP_155270473.1\|1018351_1019062_-\|integrase	tyrosine-type recombinase/integrase	A0A077KET4	Ralstonia_phage	4.9e-44	44.3
WP_051690548.1\|1019134_1019341_-	hypothetical protein	NA	NA	NA	NA
WP_153940481.1\|1019788_1020961_-	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_153940482.1\|1020957_1022391_-	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_065973572.1\|1024041_1025256_-\|transposase	ISL3 family transposase	A0A2D1GQC1	Lysinibacillus_phage	2.6e-08	23.2
1022923:1022939	attR	NA	NA	NA	NA

DBSCAN-SWA_7

1335022 : 1368583

Streptococcus_phage(33.33%)

transposase,integrase

attL 1325540:1325554|attR 1365273:1365287

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1325540:1325554	attL	NA	NA	NA	NA
WP_170286698.1\|1335022_1336336_+\|integrase	integrase family protein	NA	NA	NA	NA
WP_153940495.1\|1336875_1338378_-	apolipoprotein N-acyltransferase	NA	NA	NA	NA
WP_153940907.1\|1338384_1338999_-	thioredoxin fold domain-containing protein	NA	NA	NA	NA
WP_170286699.1\|1339062_1339848_-	DUF2063 domain-containing protein	NA	NA	NA	NA
WP_153940497.1\|1339862_1340687_-	DUF692 family protein	NA	NA	NA	NA
WP_153940498.1\|1340743_1341010_-	hypothetical protein	NA	NA	NA	NA
WP_153940499.1\|1341076_1341694_-	thioredoxin fold domain-containing protein	NA	NA	NA	NA
WP_153940500.1\|1341719_1342256_-	thioredoxin fold domain-containing protein	NA	NA	NA	NA
WP_153940501.1\|1342366_1344211_-	protein-disulfide reductase DsbD	NA	NA	NA	NA
WP_153940502.1\|1344421_1344985_-	OsmC family protein	NA	NA	NA	NA
WP_153940503.1\|1345059_1345398_-	DsrE family protein	NA	NA	NA	NA
WP_153940504.1\|1345413_1346685_-	MFS transporter	NA	NA	NA	NA
WP_153940505.1\|1346681_1347041_-	metalloregulator ArsR/SmtB family transcription factor	NA	NA	NA	NA
WP_153940506.1\|1347037_1347775_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_170286700.1\|1348019_1348553_-	TlpA family protein disulfide reductase	NA	NA	NA	NA
WP_077273537.1\|1348661_1349066_-	hypothetical protein	NA	NA	NA	NA
WP_153940508.1\|1349215_1349824_-	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_038472813.1\|1349837_1350080_-	SHOCT domain-containing protein	NA	NA	NA	NA
WP_153940509.1\|1350076_1350568_-	metalloregulator ArsR/SmtB family transcription factor	NA	NA	NA	NA
WP_153940510.1\|1350554_1351220_+	glutathione S-transferase N-terminal domain-containing protein	NA	NA	NA	NA
WP_153940511.1\|1351346_1351736_+	metalloregulator ArsR/SmtB family transcription factor	E4ZFI8	Streptococcus_phage	3.9e-11	30.3
WP_153940512.1\|1351744_1352698_+	permease	NA	NA	NA	NA
WP_153940513.1\|1352900_1353368_-	isochorismatase family protein	NA	NA	NA	NA
WP_153940514.1\|1353376_1353577_-	hypothetical protein	NA	NA	NA	NA
WP_153940515.1\|1353672_1354014_-	heavy metal-binding domain-containing protein	NA	NA	NA	NA
WP_153940516.1\|1354015_1354231_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_153940517.1\|1354267_1354921_-	hypothetical protein	NA	NA	NA	NA
WP_153940518.1\|1354932_1355790_-	hypothetical protein	NA	NA	NA	NA
WP_153940519.1\|1355794_1356145_-	hypothetical protein	NA	NA	NA	NA
WP_024895300.1\|1356161_1356350_-	hypothetical protein	NA	NA	NA	NA
WP_024895299.1\|1356382_1356958_-	hypothetical protein	NA	NA	NA	NA
WP_153940520.1\|1356954_1357314_-	hypothetical protein	NA	NA	NA	NA
WP_170286701.1\|1357316_1358354_-	ParB N-terminal domain-containing protein	A0A1B1INV8	uncultured_Mediterranean_phage	1.1e-12	34.5
WP_153940522.1\|1359597_1360905_-\|transposase	transposase	NA	NA	NA	NA
WP_081577566.1\|1361446_1362037_+\|transposase	IS607 family transposase	F9VHY9	Thermus_phage	9.8e-30	44.3
WP_081577567.1\|1362033_1363758_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	NA	NA	NA	NA
WP_153940523.1\|1363925_1364207_+	superinfection immunity protein	NA	NA	NA	NA
WP_153940524.1\|1364379_1365732_+\|transposase	IS1182 family transposase	NA	NA	NA	NA
1365273:1365287	attR	NA	NA	NA	NA
WP_081577569.1\|1366088_1366724_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_153940908.1\|1367683_1368583_-\|transposase	IS1595 family transposase	NA	NA	NA	NA

DBSCAN-SWA_8

1373802 : 1422966

Lysinibacillus_phage(14.29%)

transposase,integrase

attL 1361337:1361351|attR 1413036:1413050

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1361337:1361351	attL	NA	NA	NA	NA
WP_012387019.1\|1373802_1375017_+\|transposase	ISL3 family transposase	A0A2D1GQC1	Lysinibacillus_phage	1.8e-09	26.8
WP_153940527.1\|1375032_1376436_+	cytochrome ubiquinol oxidase subunit I	NA	NA	NA	NA
WP_153940528.1\|1376457_1377543_+	cytochrome d ubiquinol oxidase subunit II	NA	NA	NA	NA
WP_065973832.1\|1377626_1377929_+	hypothetical protein	NA	NA	NA	NA
WP_142087284.1\|1378170_1378416_+	thioredoxin family protein	NA	NA	NA	NA
WP_153940529.1\|1378501_1378960_+	hemerythrin domain-containing protein	NA	NA	NA	NA
WP_031571045.1\|1378956_1379403_+	glycine cleavage system protein H	NA	NA	NA	NA
WP_153940530.1\|1379596_1381318_-	chloride channel protein	NA	NA	NA	NA
WP_153940531.1\|1381349_1381910_-	DUF308 domain-containing protein	NA	NA	NA	NA
WP_153940532.1\|1381983_1382493_+	hypothetical protein	NA	NA	NA	NA
WP_065980270.1\|1383013_1383796_+	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_081576663.1\|1384041_1384959_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_081576664.1\|1384988_1385567_-	acyloxyacyl hydrolase	NA	NA	NA	NA
WP_153940533.1\|1385704_1386595_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_031573023.1\|1386622_1387630_-	GTP 3',8-cyclase MoaA	NA	NA	NA	NA
WP_031573020.1\|1387781_1388126_-	hypothetical protein	NA	NA	NA	NA
WP_080707830.1\|1388162_1388549_-	DUF202 domain-containing protein	NA	NA	NA	NA
WP_051690649.1\|1388541_1388817_-	hypothetical protein	NA	NA	NA	NA
WP_031573013.1\|1388865_1389567_-	NAD-dependent epimerase/dehydratase family protein	NA	NA	NA	NA
WP_031573011.1\|1389581_1390523_-	dimethyl sulfoxide reductase anchor subunit	NA	NA	NA	NA
WP_024894887.1\|1390535_1391228_-	4Fe-4S dicluster domain-containing protein	NA	NA	NA	NA
WP_153940909.1\|1391239_1394110_-	molybdopterin-dependent oxidoreductase	NA	NA	NA	NA
WP_153940534.1\|1394207_1394525_-	DUF202 domain-containing protein	NA	NA	NA	NA
WP_153940535.1\|1394869_1395136_-	hypothetical protein	NA	NA	NA	NA
WP_153940536.1\|1395219_1395528_-	hypothetical protein	NA	NA	NA	NA
WP_153940910.1\|1396023_1397304_+	hypothetical protein	NA	NA	NA	NA
WP_153940537.1\|1397629_1397983_-	hypothetical protein	NA	NA	NA	NA
WP_153940538.1\|1398206_1398560_+	hypothetical protein	NA	NA	NA	NA
WP_153940539.1\|1398631_1398928_-	hypothetical protein	NA	NA	NA	NA
WP_153940540.1\|1399041_1399683_-	hypothetical protein	NA	NA	NA	NA
WP_153940541.1\|1399792_1400101_-	type II toxin-antitoxin system PemK/MazF family toxin	NA	NA	NA	NA
WP_153940542.1\|1400094_1400331_-	AbrB family transcriptional regulator	NA	NA	NA	NA
WP_153940543.1\|1400416_1401721_-	DUF444 family protein	A0A1I9S5U5	Bacillus_phage	4.3e-09	28.5
WP_170286702.1\|1401746_1401953_-	hypothetical protein	NA	NA	NA	NA
WP_153940545.1\|1401966_1402242_-	hypothetical protein	NA	NA	NA	NA
WP_153940546.1\|1403693_1404902_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1B0VCD8	Salmonella_phage	8.0e-95	47.7
WP_024894873.1\|1407364_1407586_-	hypothetical protein	NA	NA	NA	NA
WP_024894872.1\|1407575_1407914_-	hypothetical protein	NA	NA	NA	NA
WP_024894871.1\|1408601_1409156_+	HNH endonuclease	A0A248SKR4	Salicola_phage	1.3e-44	50.3
WP_153940547.1\|1409268_1410087_+	TnsA endonuclease N-terminal domain-containing protein	NA	NA	NA	NA
WP_153940548.1\|1410070_1412146_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_153940549.1\|1412142_1413798_+	AAA family ATPase	NA	NA	NA	NA
1413036:1413050	attR	NA	NA	NA	NA
WP_153940550.1\|1414165_1415428_+\|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	1.2e-88	45.2
WP_153940551.1\|1415431_1416775_+	TniQ family protein	NA	NA	NA	NA
WP_153940552.1\|1416749_1418342_+	transcriptional antiterminator	NA	NA	NA	NA
WP_170286703.1\|1418782_1419043_+	hypothetical protein	NA	NA	NA	NA
WP_153940553.1\|1419119_1419977_+	sigma-70 family RNA polymerase sigma factor	F4YCU2	Synechococcus_phage	6.0e-36	33.8
WP_153940911.1\|1420257_1421223_+\|transposase	IS110 family transposase	A0A1S7J231	Thermus_phage	9.1e-25	31.5
WP_065972780.1\|1421880_1422966_+\|transposase	IS630 family transposase	NA	NA	NA	NA

DBSCAN-SWA_9

1448512 : 1492405

Lysinibacillus_phage(15.38%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_153940568.1\|1448512_1449544_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_170286704.1\|1450407_1450878_+\|transposase	transposase	NA	NA	NA	NA
WP_153940570.1\|1450897_1451173_-	hypothetical protein	NA	NA	NA	NA
WP_153940571.1\|1451328_1452402_-	C4-dicarboxylate ABC transporter	NA	NA	NA	NA
WP_153940572.1\|1452445_1453306_-	sigma-70 family RNA polymerase sigma factor	A0A2I5ARC7	Synechococcus_phage	1.2e-12	29.6
WP_153940573.1\|1453612_1454509_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_012387019.1\|1454729_1455944_+\|transposase	ISL3 family transposase	A0A2D1GQC1	Lysinibacillus_phage	1.8e-09	26.8
WP_153940574.1\|1456207_1457827_+	glucose-6-phosphate isomerase	NA	NA	NA	NA
WP_065973799.1\|1457923_1459138_-\|transposase	ISAzo13 family transposase	NA	NA	NA	NA
WP_081576759.1\|1459730_1460006_+	hypothetical protein	NA	NA	NA	NA
WP_153940913.1\|1462045_1463371_-	porin	NA	NA	NA	NA
WP_139112155.1\|1463951_1464335_+	hypothetical protein	NA	NA	NA	NA
WP_065974094.1\|1464331_1466311_-	type IIA DNA topoisomerase subunit B	G3M9Z3	Bacillus_virus	4.0e-83	34.5
WP_139112156.1\|1466354_1466729_-	SWF/SNF helicase family protein	A0A0U1UNQ7	Pseudomonas_phage	4.3e-15	44.0
WP_153940575.1\|1466844_1468551_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	NA	NA	NA	NA
WP_065973872.1\|1468551_1468752_-	hypothetical protein	NA	NA	NA	NA
WP_153940577.1\|1468947_1469718_-	hypothetical protein	NA	NA	NA	NA
WP_153940578.1\|1469717_1470065_-	hypothetical protein	A0A1X9HVL1	Ruegeria_phage	1.9e-12	39.5
WP_051690708.1\|1470093_1470540_-	hypothetical protein	K4F6C9	Cronobacter_phage	6.3e-29	44.9
WP_153940579.1\|1470591_1470774_-	hypothetical protein	NA	NA	NA	NA
WP_153940580.1\|1470875_1471448_-	hypothetical protein	V5YTR1	Pseudomonas_phage	1.2e-11	52.6
WP_170286705.1\|1471441_1472305_-	DUF4326 domain-containing protein	A0A0H4INX7	Stenotrophomonas_phage	2.0e-31	47.4
WP_077273528.1\|1472509_1472779_-	DUF1289 domain-containing protein	NA	NA	NA	NA
WP_065973870.1\|1472801_1473218_-	hypothetical protein	NA	NA	NA	NA
WP_031574387.1\|1474841_1475033_-	hypothetical protein	NA	NA	NA	NA
WP_031574390.1\|1475090_1475366_-	hypothetical protein	NA	NA	NA	NA
WP_031574393.1\|1475457_1476204_-	RES family NAD+ phosphorylase	NA	NA	NA	NA
WP_031574395.1\|1476200_1476602_-	DUF2384 domain-containing protein	NA	NA	NA	NA
WP_170286706.1\|1476725_1477010_+	hypothetical protein	NA	NA	NA	NA
WP_065973869.1\|1477071_1477308_-	STAS-like domain-containing protein	NA	NA	NA	NA
WP_031574404.1\|1477354_1478239_-	ATP-binding protein	NA	NA	NA	NA
WP_077273647.1\|1478462_1478969_-	uracil-DNA glycosylase	A0A1B1IWN2	uncultured_Mediterranean_phage	1.9e-05	32.9
WP_139112117.1\|1479069_1479537_-	hypothetical protein	NA	NA	NA	NA
WP_065974883.1\|1479703_1482121_-	hypothetical protein	A0A248SJQ0	Salicola_phage	1.6e-49	30.9
WP_031574433.1\|1482373_1482571_-	DNA-binding protein	NA	NA	NA	NA
WP_031574436.1\|1482622_1482901_-	hypothetical protein	NA	NA	NA	NA
WP_031574438.1\|1483719_1484055_+	hypothetical protein	NA	NA	NA	NA
WP_170286707.1\|1484065_1485967_+	DNA ligase	A0A218MKC8	uncultured_virus	8.9e-32	25.1
WP_031574444.1\|1485978_1486353_+	hypothetical protein	NA	NA	NA	NA
WP_153940583.1\|1486804_1487674_-	metallophosphoesterase	A0A291L9W7	Bordetella_phage	2.1e-20	37.4
WP_153940584.1\|1487738_1488119_-	hypothetical protein	NA	NA	NA	NA
WP_170286708.1\|1488257_1488791_-	hypothetical protein	NA	NA	NA	NA
WP_153940586.1\|1488787_1489072_-	hypothetical protein	NA	NA	NA	NA
WP_065974888.1\|1489091_1489439_-	hypothetical protein	NA	NA	NA	NA
WP_170286709.1\|1489390_1490041_-	hypothetical protein	NA	NA	NA	NA
WP_153940587.1\|1490138_1490300_-	hypothetical protein	NA	NA	NA	NA
WP_065974890.1\|1490289_1490532_-	hypothetical protein	NA	NA	NA	NA
WP_065974891.1\|1490554_1490905_-	hypothetical protein	NA	NA	NA	NA
WP_153940588.1\|1491001_1491133_-	hypothetical protein	NA	NA	NA	NA
WP_012387019.1\|1491190_1492405_-\|transposase	ISL3 family transposase	A0A2D1GQC1	Lysinibacillus_phage	1.8e-09	26.8

DBSCAN-SWA_10

1526513 : 1619498

Escherichia_phage(22.22%)

transposase,integrase,protease

attL 1522928:1522942|attR 1622979:1622994

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1522928:1522942	attL	NA	NA	NA	NA
WP_031574854.1\|1526513_1526933_-\|protease	ClpXP protease specificity-enhancing factor	NA	NA	NA	NA
1522928:1522942	attL	NA	NA	NA	NA
WP_035211301.1\|1527035_1527710_-	hypothetical protein	NA	NA	NA	NA
WP_153940605.1\|1527711_1528956_-	hypothetical protein	NA	NA	NA	NA
WP_153940606.1\|1528958_1529204_-	hypothetical protein	NA	NA	NA	NA
WP_153940607.1\|1529272_1529962_-	EAL domain-containing protein	NA	NA	NA	NA
WP_142086132.1\|1529978_1530275_-	hypothetical protein	NA	NA	NA	NA
WP_140390952.1\|1530289_1531057_-	hypothetical protein	NA	NA	NA	NA
WP_081576943.1\|1531035_1531242_-	hypothetical protein	NA	NA	NA	NA
WP_081576917.1\|1531343_1532312_-	lytic transglycosylase domain-containing protein	I6ZXX9	Escherichia_phage	3.2e-09	44.2
WP_081576918.1\|1532308_1533541_-	hypothetical protein	NA	NA	NA	NA
WP_153940608.1\|1533556_1534672_-	hypothetical protein	NA	NA	NA	NA
WP_170286712.1\|1534681_1535893_-	prepilin-type N-terminal cleavage/methylation domain-containing protein	NA	NA	NA	NA
WP_081576921.1\|1536088_1537183_-	Flp pilus assembly complex ATPase component TadA	NA	NA	NA	NA
WP_153940610.1\|1537196_1538210_-	hypothetical protein	NA	NA	NA	NA
WP_153940611.1\|1538199_1538739_-	hypothetical protein	NA	NA	NA	NA
WP_153940612.1\|1538897_1539581_-	hypothetical protein	NA	NA	NA	NA
WP_170286713.1\|1539987_1541514_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	5.1e-46	28.7
WP_077273497.1\|1542026_1543340_+\|transposase	transposase	NA	NA	NA	NA
WP_153940614.1\|1543418_1544372_-	permease	NA	NA	NA	NA
WP_153940615.1\|1544395_1544770_-	metalloregulator ArsR/SmtB family transcription factor	E4ZFI8	Streptococcus_phage	4.9e-11	31.0
WP_153940616.1\|1544896_1545562_-	glutathione S-transferase N-terminal domain-containing protein	NA	NA	NA	NA
WP_153940509.1\|1545548_1546040_+	metalloregulator ArsR/SmtB family transcription factor	NA	NA	NA	NA
WP_038472813.1\|1546036_1546279_+	SHOCT domain-containing protein	NA	NA	NA	NA
WP_153940508.1\|1546292_1546901_+	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_153940916.1\|1547050_1547461_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_170286700.1\|1547569_1548103_+	TlpA family protein disulfide reductase	NA	NA	NA	NA
WP_153940506.1\|1548347_1549085_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_153940505.1\|1549081_1549441_+	metalloregulator ArsR/SmtB family transcription factor	NA	NA	NA	NA
WP_153940504.1\|1549437_1550709_+	MFS transporter	NA	NA	NA	NA
WP_153940503.1\|1550724_1551063_+	DsrE family protein	NA	NA	NA	NA
WP_153940502.1\|1551137_1551701_+	OsmC family protein	NA	NA	NA	NA
WP_153940617.1\|1551911_1553756_+	protein-disulfide reductase DsbD	NA	NA	NA	NA
WP_153940618.1\|1553866_1554403_+	thioredoxin fold domain-containing protein	NA	NA	NA	NA
WP_153940499.1\|1554428_1555046_+	thioredoxin fold domain-containing protein	NA	NA	NA	NA
WP_153940619.1\|1555112_1555379_+	hypothetical protein	NA	NA	NA	NA
WP_153940497.1\|1555435_1556260_+	DUF692 family protein	NA	NA	NA	NA
WP_170286714.1\|1556274_1557060_+	DUF2063 domain-containing protein	NA	NA	NA	NA
WP_153940621.1\|1557152_1558409_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_153940917.1\|1558543_1559158_+	thioredoxin fold domain-containing protein	NA	NA	NA	NA
WP_153940622.1\|1561230_1561704_-	hypothetical protein	NA	NA	NA	NA
WP_170286715.1\|1561690_1563697_-	hypothetical protein	NA	NA	NA	NA
WP_153940624.1\|1563852_1565838_-	hypothetical protein	NA	NA	NA	NA
WP_153940625.1\|1565842_1567075_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_153940626.1\|1567242_1567497_-	hypothetical protein	NA	NA	NA	NA
WP_153940627.1\|1567506_1567671_-	hypothetical protein	NA	NA	NA	NA
WP_153940628.1\|1567710_1567998_-	hypothetical protein	NA	NA	NA	NA
WP_153940629.1\|1567999_1568149_-	hypothetical protein	NA	NA	NA	NA
WP_153940630.1\|1568145_1568742_-	HAD family hydrolase	NA	NA	NA	NA
WP_153940631.1\|1568921_1569110_-	hypothetical protein	NA	NA	NA	NA
WP_153940632.1\|1569113_1569956_-	thioredoxin fold domain-containing protein	NA	NA	NA	NA
WP_081576925.1\|1569979_1570207_-	hypothetical protein	NA	NA	NA	NA
WP_153940633.1\|1570199_1570667_-	hypothetical protein	NA	NA	NA	NA
WP_170286716.1\|1570742_1571609_-	hypothetical protein	NA	NA	NA	NA
WP_024893614.1\|1573316_1574051_+	ATP-binding protein	A0A2L1IVB6	Escherichia_phage	1.1e-35	37.8
1572757:1572771	attR	NA	NA	NA	NA
WP_153940635.1\|1574304_1575084_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
1572757:1572771	attR	NA	NA	NA	NA
WP_170286717.1\|1575127_1575418_-	hypothetical protein	NA	NA	NA	NA
WP_140391020.1\|1576057_1576513_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_153940637.1\|1576493_1577813_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_153940638.1\|1577861_1578962_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_153940639.1\|1578958_1579396_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_153940640.1\|1579405_1581214_+	hypothetical protein	NA	NA	NA	NA
WP_153940641.1\|1581200_1581470_+	GIY-YIG nuclease family protein	F2NZ06	Diadromus_pulchellus_ascovirus	6.3e-08	40.5
WP_153940642.1\|1581751_1581931_+	hypothetical protein	NA	NA	NA	NA
WP_153940643.1\|1581934_1582510_+	hypothetical protein	NA	NA	NA	NA
WP_153940644.1\|1582531_1583344_-	hypothetical protein	NA	NA	NA	NA
WP_153940645.1\|1583340_1584060_-	hypothetical protein	NA	NA	NA	NA
WP_153940646.1\|1584367_1585750_-	DHA2 family efflux MFS transporter permease subunit	NA	NA	NA	NA
WP_153940647.1\|1586587_1588021_-	bifunctional 2-methylcitrate dehydratase/aconitate hydratase	NA	NA	NA	NA
WP_153940648.1\|1589283_1590168_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_170286718.1\|1591085_1593509_+	DEAD/DEAH box helicase	NA	NA	NA	NA
WP_153940650.1\|1593738_1595067_+\|transposase	transposase	NA	NA	NA	NA
WP_153940651.1\|1595137_1598185_+	N-6 DNA methylase	A0A2R2ZGH5	Clostridioides_phage	1.5e-28	23.6
WP_170286719.1\|1598447_1598723_-	DUF559 domain-containing protein	NA	NA	NA	NA
WP_170286720.1\|1599006_1599201_-	hypothetical protein	NA	NA	NA	NA
WP_170286721.1\|1599392_1599764_-	type IV secretion system DNA-binding domain-containing protein	NA	NA	NA	NA
WP_153940654.1\|1599992_1600730_-	hypothetical protein	NA	NA	NA	NA
WP_153940655.1\|1600743_1602075_-\|transposase	ISL3 family transposase	A0A2D1GQC1	Lysinibacillus_phage	2.5e-89	40.1
WP_153940656.1\|1602078_1602819_-	hypothetical protein	NA	NA	NA	NA
WP_153940657.1\|1602818_1603979_-	hypothetical protein	A0A2L1IZ21	Streptomyces_phage	2.9e-94	49.7
WP_153940658.1\|1604201_1606298_-	UvrD-helicase domain-containing protein	A7KV33	Bacillus_phage	6.5e-92	34.0
WP_153940659.1\|1606319_1606898_-	hypothetical protein	NA	NA	NA	NA
WP_051690672.1\|1606930_1607512_-	nucleoside 2-deoxyribosyltransferase	NA	NA	NA	NA
WP_153940660.1\|1607575_1607764_-	hypothetical protein	NA	NA	NA	NA
WP_153940661.1\|1607784_1608510_-	hypothetical protein	NA	NA	NA	NA
WP_153940662.1\|1608571_1609702_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_153940663.1\|1609691_1611341_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_153940918.1\|1611416_1613258_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_153940664.1\|1614007_1615459_-	sigma 54-interacting transcriptional regulator	NA	NA	NA	NA
WP_126605065.1\|1615643_1616606_+	hydrogenase	NA	NA	NA	NA
WP_153940665.1\|1616657_1618256_+	nickel-dependent hydrogenase large subunit	NA	NA	NA	NA
WP_153940666.1\|1618347_1618674_+	hypothetical protein	NA	NA	NA	NA
WP_153940667.1\|1618689_1619022_+	hypothetical protein	NA	NA	NA	NA
WP_153940668.1\|1619024_1619498_+\|protease	hydrogenase maturation protease	NA	NA	NA	NA
1622979:1622994	attR	NA	NA	NA	NA

DBSCAN-SWA_11

2257937 : 2308727

Morganella_phage(15.38%)

transposase,integrase

attL 2266186:2266245|attR 2314549:2315719

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_031568969.1\|2257937_2258846_-\|integrase	tyrosine-type recombinase/integrase	A0A1B1IQT7	uncultured_Mediterranean_phage	5.2e-14	30.4
WP_051690428.1\|2259040_2259379_+	hypothetical protein	NA	NA	NA	NA
WP_077273660.1\|2259434_2260376_-	nucleotidyl transferase AbiEii/AbiGii toxin family protein	NA	NA	NA	NA
WP_035209402.1\|2260365_2260908_-	hypothetical protein	NA	NA	NA	NA
WP_051690425.1\|2260974_2263368_-	type IV secretory system conjugative DNA transfer family protein	NA	NA	NA	NA
WP_031568932.1\|2263522_2264659_+	hypothetical protein	NA	NA	NA	NA
WP_031568930.1\|2264655_2265669_-\|integrase	site-specific integrase	W6MYA3	Pseudomonas_phage	5.8e-54	41.3
WP_153940443.1\|2266185_2267271_-\|transposase	IS630 family transposase	NA	NA	NA	NA
2266186:2266245	attL	NA	NA	NA	NA
WP_010638078.1\|2267992_2268325_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_140391080.1\|2268423_2270004_-	DUF3987 domain-containing protein	NA	NA	NA	NA
WP_080707884.1\|2270297_2270801_+	cupin domain-containing protein	NA	NA	NA	NA
WP_010638071.1\|2271190_2271508_+	hypothetical protein	NA	NA	NA	NA
WP_010638069.1\|2271592_2272549_+	DUF932 domain-containing protein	A0A218M383	Acidovorax_phage	5.8e-48	37.7
WP_031576183.1\|2272678_2273632_+	YqaJ viral recombinase family protein	A6XMH8	Bacillus_virus	4.3e-59	42.7
WP_031576181.1\|2273628_2274492_+	hypothetical protein	NA	NA	NA	NA
WP_153940798.1\|2274756_2276931_-	hypothetical protein	NA	NA	NA	NA
WP_153940799.1\|2276990_2277872_-	NACHT domain-containing protein	NA	NA	NA	NA
WP_031575636.1\|2278186_2279299_-	J domain-containing protein	NA	NA	NA	NA
WP_031575634.1\|2279440_2280724_-	Y-family DNA polymerase	I6RSM4	Salmonella_phage	1.8e-92	45.4
WP_031575632.1\|2280730_2281204_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	1.6e-27	49.2
WP_031575630.1\|2281196_2281451_-	hypothetical protein	NA	NA	NA	NA
WP_031575628.1\|2281629_2282322_+	hypothetical protein	NA	NA	NA	NA
WP_010638039.1\|2282501_2282741_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_029316014.1\|2282740_2283151_+	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_153940366.1\|2284532_2285795_+\|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	2.4e-89	45.4
WP_153940800.1\|2286136_2287150_-	hypothetical protein	NA	NA	NA	NA
WP_010638032.1\|2287154_2287481_-	H-NS histone family protein	NA	NA	NA	NA
WP_153940801.1\|2287623_2288424_-	EcsC family protein	NA	NA	NA	NA
WP_010638028.1\|2288374_2289991_-	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	3.9e-105	43.4
WP_010638027.1\|2290026_2290245_-	hypothetical protein	NA	NA	NA	NA
WP_010638026.1\|2290241_2290763_-	zeta toxin family protein	NA	NA	NA	NA
WP_010638024.1\|2290765_2292034_-	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	5.2e-20	32.5
WP_153940802.1\|2292142_2295109_-	HsdR family type I site-specific deoxyribonuclease	NA	NA	NA	NA
WP_010638019.1\|2295205_2295469_-	superinfection immunity protein	NA	NA	NA	NA
WP_010638017.1\|2295599_2295899_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_031570374.1\|2296016_2296694_-	MOSC domain-containing protein	NA	NA	NA	NA
WP_031570372.1\|2296690_2297032_-	hypothetical protein	NA	NA	NA	NA
WP_010638012.1\|2297333_2297732_-	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_010638010.1\|2297731_2297950_-	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_010638008.1\|2298099_2298366_-	hypothetical protein	NA	NA	NA	NA
WP_031570363.1\|2298502_2300686_-	ATP-dependent RecD-like DNA helicase	A0A1P8DII4	Virus_Rctr197k	4.7e-53	32.8
WP_031570360.1\|2300774_2301458_+	SOS response-associated peptidase	B7SYF4	Stenotrophomonas_phage	3.4e-18	35.0
WP_081577267.1\|2303077_2304397_+	sensor domain-containing diguanylate cyclase	NA	NA	NA	NA
WP_031570032.1\|2304427_2305489_-	inovirus-type Gp2 protein	NA	NA	NA	NA
WP_170286746.1\|2305990_2307190_-\|integrase	tyrosine-type recombinase/integrase	A0A1W6JPG6	Morganella_phage	2.1e-39	31.1
WP_153940376.1\|2307464_2308727_-\|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	3.4e-88	44.9
2314549:2315719	attR	NA	NA	NA	NA

DBSCAN-SWA_12

2385858 : 2425983

Bacillus_virus(50.0%)

transposase,integrase

attL 2399696:2399712|attR 2433072:2433088

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_153940809.1\|2385858_2386989_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_153940810.1\|2386978_2388628_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_170286765.1\|2388709_2390545_+\|integrase	integrase	NA	NA	NA	NA
WP_081577243.1\|2391178_2391550_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_081577242.1\|2391553_2391784_+	SHOCT domain-containing protein	NA	NA	NA	NA
WP_081577261.1\|2391813_2392380_+	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_051690768.1\|2392399_2392678_+	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_031575837.1\|2393081_2393396_+	DUF2282 domain-containing protein	NA	NA	NA	NA
WP_081577240.1\|2393489_2394365_+	DUF692 domain-containing protein	NA	NA	NA	NA
WP_081577239.1\|2394357_2395071_+	putative DNA-binding domain-containing protein	NA	NA	NA	NA
WP_153940928.1\|2395196_2397074_+	protein-disulfide reductase DsbD	NA	NA	NA	NA
WP_153940929.1\|2397140_2397710_+	thioredoxin fold domain-containing protein	NA	NA	NA	NA
WP_153940771.1\|2397736_2398369_+	thioredoxin fold domain-containing protein	NA	NA	NA	NA
WP_153940772.1\|2398475_2399093_+	thioredoxin fold domain-containing protein	NA	NA	NA	NA
2399696:2399712	attL	NA	NA	NA	NA
WP_153940812.1\|2399734_2400184_-	DUF2442 domain-containing protein	NA	NA	NA	NA
WP_035210192.1\|2400198_2400417_-	DUF4160 domain-containing protein	NA	NA	NA	NA
WP_031571354.1\|2400469_2401099_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_031571358.1\|2401759_2402020_-	hypothetical protein	NA	NA	NA	NA
WP_139110685.1\|2402194_2402386_-	hypothetical protein	NA	NA	NA	NA
WP_024895462.1\|2402411_2402606_+	hypothetical protein	NA	NA	NA	NA
WP_010636705.1\|2403745_2403994_+	hypothetical protein	NA	NA	NA	NA
WP_077218551.1\|2404109_2404358_-	hypothetical protein	NA	NA	NA	NA
WP_153940478.1\|2404894_2405566_+	hypothetical protein	NA	NA	NA	NA
WP_153940813.1\|2405789_2406683_-	L,D-transpeptidase family protein	NA	NA	NA	NA
WP_051690537.1\|2406938_2409233_-	EAL domain-containing protein	G3MA91	Bacillus_virus	2.8e-24	39.0
WP_153940781.1\|2410546_2411542_-	CZB domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	5.0e-10	53.8
WP_031573920.1\|2411576_2411828_-	hypothetical protein	NA	NA	NA	NA
WP_153940814.1\|2411894_2414993_-	EAL domain-containing protein	G3MA91	Bacillus_virus	1.1e-23	39.5
WP_153940815.1\|2415227_2415611_-	hypothetical protein	NA	NA	NA	NA
WP_031568562.1\|2419340_2419979_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_051690403.1\|2420023_2421376_-	amino acid permease	NA	NA	NA	NA
WP_153940376.1\|2422162_2423425_-\|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	3.4e-88	44.9
WP_031576109.1\|2424382_2424586_+	hypothetical protein	NA	NA	NA	NA
WP_153940443.1\|2424897_2425983_-\|transposase	IS630 family transposase	NA	NA	NA	NA
2433072:2433088	attR	NA	NA	NA	NA

DBSCAN-SWA_13

2612433 : 2620405

uncultured_Caudovirales_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_031574247.1\|2612433_2613714_-	phosphopyruvate hydratase	W6LP63	Streptococcus_phage	2.7e-141	59.3
WP_081577199.1\|2613710_2614556_-	3-deoxy-8-phosphooctulonate synthase	E3T537	Cafeteria_roenbergensis_virus	7.9e-57	45.2
WP_153940842.1\|2614552_2616184_-	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	2.5e-160	52.3
WP_010642205.1\|2616336_2617377_-	NAD(P)-dependent alcohol dehydrogenase	A0A2K9L7I1	Tupanvirus	1.1e-76	42.9
WP_081577197.1\|2617408_2618080_-	cupin domain-containing protein	NA	NA	NA	NA
WP_153940843.1\|2618161_2619469_-	arsenical efflux pump membrane protein ArsB	A0A2H4J144	uncultured_Caudovirales_phage	2.1e-133	59.7
WP_081577195.1\|2619561_2619927_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_010640437.1\|2619913_2620405_+	arsenate reductase ArsC	A0A2H4J8A6	uncultured_Caudovirales_phage	9.0e-37	51.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP045571

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection