CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP045931	Streptococcus pneumoniae strain AUSMDU00010538 chromosome, complete genome	5 crisprs	DEDDh,PrimPol,cas3,DinG,RT	0	0	11	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP045931_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045931_1

110777-110872

Orphan

Consensus_repeat	Method
AATGTGTAAGATTTTTATATATAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045931_1

>merge|NZ_CP045931|1|110777-110872|CRISPRCasFinder
AATGTGTAAGATTTTTATATATAATTTTTCTACACATACATTGTACATCTAAAAGAAAGCCCTGTCAAGAGAAATGTGTAAAATTTTTATATATAA

>NZ_CP045931|1|1|110777-110872|CRISPRCasFinder
AATGTGTAAGATTTTTATATATAA	TTTTTCTACACATACATTGTACATCTAAAAGAAAGCCCTGTCAAGAGA
AATGTGTAAAATTTTTATATATAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045931.1\|WP_001035700.1\|113320_115171_+\|polysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|224011
NZ_CP045931.1\|WP_000808456.1\|107821_108886_-\|membrane-protein	unknown	unknown	gnl\|CDD\|370966
NZ_CP045931.1\|WP_078139066.1\|119995_120754_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045931.1\|WP_000744892.1\|110897_112064_-\|CynX/NimT-family-MFS-transporter	unknown	unknown	gnl\|CDD\|340897
NZ_CP045931.1\|WP_000500040.1\|116172_117045_-\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	unknown	unknown	gnl\|CDD\|129801
NZ_CP045931.1\|WP_001861316.1\|118591_118912_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045931.1\|WP_000273864.1\|110432_110759_-\|PadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224609
NZ_CP045931.1\|WP_000096200.1\|112121_113279_+\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|133016
NZ_CP045931.1\|WP_000200892.1\|115518_116151_-\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|319798
NZ_CP045931.1\|WP_047475444.1\|119675_120029_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045931.1\|WP_001030029.1\|103280_104267_+\|rhodanese-related-sulfurtransferase	unknown	unknown	gnl\|CDD\|234663
NZ_CP045931.1\|WP_000800407.1\|101533_103009_+\|DUF3502-domain-containing-protein	unknown	unknown	gnl\|CDD\|378792
NZ_CP045931.1\|WP_001233695.1\|108948_109860_-\|DUF4097-domain-containing-protein	unknown	unknown	gnl\|CDD\|372574
NZ_CP045931.1\|WP_153228097.1\|101349_101490_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045931.1\|WP_000838912.1\|117053_117725_-\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta	unknown	unknown	gnl\|CDD\|224674
NZ_CP045931.1\|WP_001140354.1\|104541_105402_+\|DUF4299-domain-containing-protein	unknown	unknown	gnl\|CDD\|339103
NZ_CP045931.1\|WP_001813319.1\|106059_106839_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045931.1\|WP_000836444.1\|117966_118539_+\|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|212030
NZ_CP045931.1\|WP_000198697.1\|109852_110446_-\|DUF1700-domain-containing-protein	unknown	unknown	gnl\|CDD\|227053
NZ_CP045931.1\|WP_001257240.1\|107387_107585_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|213179

Protein	Function_ID	Function_description	E-value
NZ_CP045931.1\|WP_001035700.1\|113320_115171_+\|polysaccharide-biosynthesis-protein	gnl\|CDD\|224011	COG1086, COG1086, Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	0
NZ_CP045931.1\|WP_000808456.1\|107821_108886_-\|membrane-protein	gnl\|CDD\|370966	pfam10310, DUF5427, Family of unknown function (DUF5427). This is a domain of unknown function. Family members found in Saccharomyces cerevisiae, are synthetic lethal with genes involved in maintenance of telomere capping. However, experimental evidence is yet to verify the exact function of family members and the domain.	5.27948e-06
NZ_CP045931.1\|WP_000744892.1\|110897_112064_-\|CynX/NimT-family-MFS-transporter	gnl\|CDD\|340897	cd17339, MFS_NIMT_CynX_like, 2-nitroimidazole and cyanate transporters and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Escherichia coli 2-nitroimidazole transporter (NIMT) and cyanate transport protein CynX, and similar proteins. NIMT, also called YeaN, confers resistance to 2-nitroimidazole, the antibacterial and antifungal antibiotic, by mediating the active efflux of this compound. CynX is part of an active transport system that transports exogenous cyanate into E. coli cells. The NIMT/CynX-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	7.61054e-125
NZ_CP045931.1\|WP_000500040.1\|116172_117045_-\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	gnl\|CDD\|129801	TIGR00718, Probable_L-serine_dehydratase_alpha_chain, L-serine dehydratase, iron-sulfur-dependent, alpha subunit. This enzyme is also called serine deaminase. L-serine dehydratase converts serine into pyruvate in the gluconeogenesis pathway from serine. This model describes the alpha chain of an iron-sulfur-dependent L-serine dehydratase, found in Bacillus subtilis. A fairly deep split in a UPGMA tree separates members of this family of alpha chains from the homologous region of single chain forms such as found in Escherichia coli. This family of enzymes is not homologous to the pyridoxal phosphate-dependent threonine deaminases and eukaryotic serine deaminases. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	1.44295e-105
NZ_CP045931.1\|WP_000273864.1\|110432_110759_-\|PadR-family-transcriptional-regulator	gnl\|CDD\|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	3.12912e-19
NZ_CP045931.1\|WP_000096200.1\|112121_113279_+\|glycosyltransferase-family-2-protein	gnl\|CDD\|133016	cd02525, Succinoglycan_BP_ExoA, ExoA is involved in the biosynthesis of succinoglycan. Succinoglycan Biosynthesis Protein ExoA catalyzes the formation of a beta-1,3 linkage of the second sugar (glucose) of the succinoglycan with the galactose on the lipid carrie. Succinoglycan is an acidic exopolysaccharide that is important for invasion of the nodules. Succinoglycan is a high-molecular-weight polymer composed of repeating octasaccharide units. These units are synthesized on membrane-bound isoprenoid lipid carriers, beginning with galactose followed by seven glucose molecules, and modified by the addition of acetate, succinate, and pyruvate. ExoA is a membrane protein with a transmembrance domain at c-terminus.	4.49371e-109
NZ_CP045931.1\|WP_000200892.1\|115518_116151_-\|HAD-family-hydrolase	gnl\|CDD\|319798	cd04302, HAD_5NT, haloacid dehalogenase (HAD)-like 5'-nucleotidases similar to the Pseudomonas aeruginosa PA0065. 5'-nucleotidases dephosphorylate nucleoside 5'-monophosphates to nucleosides and inorganic phosphate. Purified Pseudomonas aeruginosa PA0065 displayed high activity toward 5'-UMP and 5'-IMP, significant activity against 5'-XMP and 5'-TMP, and low activity against 5'-CMP. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	4.4095e-97
NZ_CP045931.1\|WP_000800407.1\|101533_103009_+\|DUF3502-domain-containing-protein	gnl\|CDD\|378792	pfam12010, DUF3502, Domain of unknown function (DUF3502). This presumed domain is functionally uncharacterized. This domain is found in bacteria. This domain is about 140 amino acids in length. This domain is found associated with pfam01547.	4.24398e-44
NZ_CP045931.1\|WP_001233695.1\|108948_109860_-\|DUF4097-domain-containing-protein	gnl\|CDD\|372574	pfam13349, DUF4097, Putative adhesin. This has a putative all-beta structure with a twenty-residue repeat with a highly conserved repeating GD, gly-asp, motif. It may form part of a bacterial adhesin.	1.3697e-39
NZ_CP045931.1\|WP_000838912.1\|117053_117725_-\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta	gnl\|CDD\|224674	COG1760, SdaA, L-serine deaminase [Amino acid transport and metabolism].	1.1908e-89
NZ_CP045931.1\|WP_001140354.1\|104541_105402_+\|DUF4299-domain-containing-protein	gnl\|CDD\|339103	pfam14132, DUF4299, Domain of unknown function (DUF4299). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 275 and 313 amino acids in length. There are two conserved sequence motifs: RGF and DAY. There are two completely conserved residues (P and D) that may be functionally important.	7.58045e-121
NZ_CP045931.1\|WP_001257240.1\|107387_107585_+\|hypothetical-protein	gnl\|CDD\|213179	cd00267, ABC_ATPase, ATP-binding cassette transporter nucleotide-binding domain. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	1.13225e-11
NZ_CP045931.1\|WP_000836444.1\|117966_118539_+\|LysM-peptidoglycan-binding-domain-containing-protein	gnl\|CDD\|212030	cd00118, LysM, Lysin Motif is a small domain involved in binding peptidoglycan. LysM, a small globular domain with approximately 40 amino acids, is a widespread protein module involved in binding peptidoglycan in bacteria and chitin in eukaryotes. The domain was originally identified in enzymes that degrade bacterial cell walls, but proteins involved in many other biological functions also contain this domain. It has been reported that the LysM domain functions as a signal for specific plant-bacteria recognition in bacterial pathogenesis. Many of these enzymes are modular and are composed of catalytic units linked to one or several repeats of LysM domains. LysM domains are found in bacteria and eukaryotes.	5.74081e-13
NZ_CP045931.1\|WP_000198697.1\|109852_110446_-\|DUF1700-domain-containing-protein	gnl\|CDD\|227053	COG4709, COG4709, Predicted membrane protein [Function unknown].	7.13921e-64
NZ_CP045931.1\|WP_001030029.1\|103280_104267_+\|rhodanese-related-sulfurtransferase	gnl\|CDD\|234663	PRK00142, PRK00142, rhodanese-related sulfurtransferase.	0

>NZ_CP045931.1|WP_000273864.1|110432_110759_-|PadR-family-transcriptional-regulator
MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLYPILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGSIRHDKN
>NZ_CP045931.1|WP_000198697.1|109852_110446_-|DUF1700-domain-containing-protein
MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEELIASLGTPKEVAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILVTLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGASSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA
>NZ_CP045931.1|WP_001233695.1|108948_109860_-|DUF4097-domain-containing-protein
MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVYDSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTLSLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTIINASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAENIQVHGKVELTAEDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYKTEKTDVKDQLIARSDDNIDLISTPSRR
>NZ_CP045931.1|WP_000808456.1|107821_108886_-|membrane-protein
MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIGKNTQVEEEVSQAEVELESQQEEKIETPEGGEARTEIEEKKASNSTEEEPDLSKETEKVTIAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIKSPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLTLFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIASFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIILLFFVAEVALIGDYLRILAFL
>NZ_CP045931.1|WP_001257240.1|107387_107585_+|hypothetical-protein
MRSLSQEKDIYSFDEPTGNLDRNSTELFLNEVEKLVNEEKIVIVVTHDKDVIARASKVINMDEFH
>NZ_CP045931.1|WP_001813319.1|106059_106839_+|hypothetical-protein
MSIYRRLTRFYIPQKLNDYIGQKKSKFIPFLPNPVLITKVMLYCSPILALFLCYACYDIQLNISKVPRNIITFLVGSVVAIIHELLIMIYYLKSGRVPGRIYIRIVYLVVISFGTEWGASYSEKKVFRTTMFLFSMISIFYLSAIFFMIFYLLQYLKLYTAAYYTSIYAVGTLIFAFINAYPFLLKTDGYILYQEFFGIYKIRSLFFKTLFYCIGIRNNLKLQEVVKRNNLKTYIWDLFFIISIIGLLYILYSSIRFII
>NZ_CP045931.1|WP_001140354.1|104541_105402_+|DUF4299-domain-containing-protein
MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQPLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYTGTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLAQFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLVDKEVQWEIDLVQITGDGSKPEDYESIARLDYAKFLEVLPPSFYHQLDANQIEVQPILDKDFKTLAQEK
>NZ_CP045931.1|WP_001030029.1|103280_104267_+|rhodanese-related-sulfurtransferase
MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADEGINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEESEQAFKKMFVRYKKEIVHLGLEDNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRNFRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKDPEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILTSEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV
>NZ_CP045931.1|WP_000800407.1|101533_103009_+|DUF3502-domain-containing-protein
MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIKMYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAFADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQNFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPVANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQDTWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEKSMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNWILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINTGTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK
>NZ_CP045931.1|WP_153228097.1|101349_101490_-|hypothetical-protein
MILYSMKIKEQTRKLAAGCSKHCFEVVDKTDEVSYIYLRQGDVDAV
>NZ_CP045931.1|WP_000744892.1|110897_112064_-|CynX/NimT-family-MFS-transporter
MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSLGVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLMVGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGLILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFYTAMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVSLAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGLSQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIDILMTVALFTVDRADKIL
>NZ_CP045931.1|WP_000096200.1|112121_113279_+|glycosyltransferase-family-2-protein
MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIVISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIRLYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTETFVMNNVAIIQQGEFVCGGPRPTIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNEQLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQFKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGFLIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKRTIIYLDKISQINKNML
>NZ_CP045931.1|WP_001035700.1|113320_115171_+|polysaccharide-biosynthesis-protein
MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILFYGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLSYSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGAGDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIERVIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGRQEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVYHELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFKNNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTYCAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAKDGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVDNQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE
>NZ_CP045931.1|WP_000200892.1|115518_116151_-|HAD-family-hydrolase
MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIRGFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPLYITTTKDTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIIIGDTKFDMLGARETGIQKLAITWGFGEQADLLNYQPDYIAHKPLEVLAYFQ
>NZ_CP045931.1|WP_000500040.1|116172_117045_-|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha
MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLMERNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNEHNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASISGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEVPCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLATTPTGRRLQKEIFGE
>NZ_CP045931.1|WP_000838912.1|117053_117725_-|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta
MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPTEVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKDSNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDIPGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHNVNFFK
>NZ_CP045931.1|WP_000836444.1|117966_118539_+|LysM-peptidoglycan-binding-domain-containing-protein
MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLSEIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETVSAPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY
>NZ_CP045931.1|WP_001861316.1|118591_118912_-|hypothetical-protein
MQRLEVYKNYQHLYDLRMTILLNLSTLYLYNQDKNMCKQICYTLLEDAKNKKSYDRLAICYVRIGICRDDAKLIQKGFSLLELTEETSMLSHLKKEVETHYQPKKL
>NZ_CP045931.1|WP_047475444.1|119675_120029_+|hypothetical-protein
MELVLPNNYVVIDEEEMMYLDGGAYLSKRACQGICAALAMSPGTFIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGVLAGAAGRIAYCIGYGALNRGCDINGNPYPWDGFISATVR
>NZ_CP045931.1|WP_078139066.1|119995_120754_+|hypothetical-protein
MGWIHICDSKMSNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSIVSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHLIRKDFDIKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVDNHVLTLIFLIKICADTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSILLLFSNFSVPFIKEKEYELFKNKK

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Crispr_ID: NZ_CP045931_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045931_2

1048023-1048134

Orphan

Consensus_repeat	Method
GATGAAAATGGAAACTTGATTGAACCACCTGTTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045931_2

>merge|NZ_CP045931|2|1048023-1048134|CRISPRCasFinder
GATGAAAATGGAAACTTGATTGAACCACCTGTTAACGACATCCCAGAATATACTGAGCCAGTAGGTACAACAGGAGTGGATGAAAATGGAAACTTGATTGAGCCACCTGTTA

>NZ_CP045931|2|2|1048023-1048134|CRISPRCasFinder
GATGAAAATGGAAACTTGATTGAACCACCTGTTA	ACGACATCCCAGAATATACTGAGCCAGTAGGTACAACAGGAGTG
GATGAAAATGGAAACTTGATTGAGCCACCTGTTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045931.1\|WP_000278526.1\|1063926_1065288_-\|sodium-coupled-multidrug-efflux-MATE-transporter-PdrM	unknown	unknown	gnl\|CDD\|240536
NZ_CP045931.1\|WP_000131080.1\|1028606_1029053_-\|YueI-family-protein	unknown	unknown	gnl\|CDD\|227793
NZ_CP045931.1\|WP_000392544.1\|1054456_1056007_+\|ClC-family-H(+)/Cl(-)-exchange-transporter	unknown	unknown	gnl\|CDD\|238504
NZ_CP045931.1\|WP_078101594.1\|1027794_1028610_+\|glycerate-kinase	unknown	unknown	gnl\|CDD\|224840
NZ_CP045931.1\|WP_000174775.1\|1039500_1040679_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045931.1\|WP_000201099.1\|1053661_1054441_+\|ribonuclease-HII	unknown	unknown	gnl\|CDD\|234574
NZ_CP045931.1\|WP_000022813.1\|1029216_1030521_+\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NZ_CP045931.1\|WP_000767259.1\|1035635_1039286_+\|helicase-exonuclease-AddAB-subunit-AddA	unknown	unknown	gnl\|CDD\|274299
NZ_CP045931.1\|WP_000697290.1\|1025660_1027094_+\|glycogen-synthase-GlgA	unknown	unknown	gnl\|CDD\|234809
NZ_CP045931.1\|WP_044811956.1\|1030658_1031105_-\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271189
NZ_CP045931.1\|WP_001162695.1\|1058786_1060490_-\|dihydrolipoyl-dehydrogenase	unknown	unknown	gnl\|CDD\|273568
NZ_CP045931.1\|WP_000448719.1\|1061796_1062789_-\|alpha-ketoacid-dehydrogenase-subunit-beta	unknown	unknown	gnl\|CDD\|223101
NZ_CP045931.1\|WP_000752697.1\|1060535_1061579_-\|dihydrolipoamide-acetyltransferase	unknown	unknown	gnl\|CDD\|184847
NZ_CP045931.1\|WP_000417164.1\|1040887_1047313_+\|YSIRK-type-signal-peptide-containing-protein	unknown	unknown	gnl\|CDD\|369436
NZ_CP045931.1\|WP_000873991.1\|1057733_1058723_-\|lipoate--protein-ligase	unknown	unknown	gnl\|CDD\|161920
NZ_CP045931.1\|WP_000817884.1\|1056590_1057661_+\|tyrosine-recombinase-XerS	unknown	unknown	gnl\|CDD\|235339
NZ_CP045931.1\|WP_000201315.1\|1052823_1053675_+\|ribosome-biogenesis-GTPase-YlqF	unknown	unknown	gnl\|CDD\|236570
NZ_CP045931.1\|WP_000772331.1\|1032363_1035639_+\|ATP-dependent-nuclease-subunit-B	unknown	unknown	gnl\|CDD\|274291
NZ_CP045931.1\|WP_000687033.1\|1024524_1025664_+\|glucose-1-phosphate-adenylyltransferase-subunit-GlgD	unknown	unknown	gnl\|CDD\|273966
NZ_CP045931.1\|WP_000105363.1\|1062804_1063773_-\|thiamine-pyrophosphate-dependent-dehydrogenase-E1-component-subunit-alpha	unknown	unknown	gnl\|CDD\|223997

Protein	Function_ID	Function_description	E-value
NZ_CP045931.1\|WP_000278526.1\|1063926_1065288_-\|sodium-coupled-multidrug-efflux-MATE-transporter-PdrM	gnl\|CDD\|240536	cd13131, MATE_NorM_like, Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Vibrio cholerae NorM and functions most likely as a multidrug efflux pump, removing xenobiotics from the interior of the cell. The pump utilizes a cation gradient across the membrane to facilitate the export process. NorM appears to bind monovalent cations in an outward-facing conformation and may subsequently cycle through an inward-facing and outward-facing conformation to capture and release its substrate.	3.66107e-155
NZ_CP045931.1\|WP_000131080.1\|1028606_1029053_-\|YueI-family-protein	gnl\|CDD\|227793	COG5506, COG5506, Uncharacterized conserved protein [Function unknown].	3.70652e-56
NZ_CP045931.1\|WP_000392544.1\|1054456_1056007_+\|ClC-family-H(+)/Cl(-)-exchange-transporter	gnl\|CDD\|238504	cd01031, EriC, ClC chloride channel EriC. This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked proton utilization. As shown for Escherichia coli EriC, these channels can counterbalance the electric current produced by the outwardly directed virtual proton pump linked to amino acid decarboxylation. The EriC proteins belong to the ClC superfamily of chloride ion channels, which share a unique double-barreled architecture and voltage-dependent gating mechanism. The voltage-dependent gating is conferred by the permeating anion itself, acting as the gating charge. In Escherichia coli EriC, a glutamate residue that protrudes into the pore is thought to participate in gating by binding to a Cl- ion site within the selectivity filter.	2.37582e-164
NZ_CP045931.1\|WP_078101594.1\|1027794_1028610_+\|glycerate-kinase	gnl\|CDD\|224840	COG1929, COG1929, Glycerate kinase [Carbohydrate transport and metabolism].	1.64591e-69
NZ_CP045931.1\|WP_000873991.1\|1057733_1058723_-\|lipoate--protein-ligase	gnl\|CDD\|161920	TIGR00545, Probable_lipoate-protein_ligase_A, lipoyltransferase and lipoate-protein ligase. One member of this group of proteins is bovine lipoyltransferase, which transfers the lipoyl group from lipoyl-AMP to the specific Lys of lipoate-dependent enzymes. However, it does not first activate lipoic acid with ATP to create lipoyl-AMP and pyrophosphate. Another member of this group, lipoate-protein ligase A from E. coli, catalyzes both the activation and the transfer of lipoate. Homology between the two is full-length, except for the bovine mitochondrial targeting signal, but is strongest toward the N-terminus. [Protein fate, Protein modification and repair].	1.03387e-97
NZ_CP045931.1\|WP_000201099.1\|1053661_1054441_+\|ribonuclease-HII	gnl\|CDD\|234574	PRK00015, rnhB, ribonuclease HII; Validated.	5.65115e-109
NZ_CP045931.1\|WP_000022813.1\|1029216_1030521_+\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NZ_CP045931.1\|WP_000767259.1\|1035635_1039286_+\|helicase-exonuclease-AddAB-subunit-AddA	gnl\|CDD\|274299	TIGR02785, ATP-dependent_helicase/nuclease_subunit_A, helicase-exonuclease AddAB, AddA subunit, Firmicutes type. AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP045931.1\|WP_000697290.1\|1025660_1027094_+\|glycogen-synthase-GlgA	gnl\|CDD\|234809	PRK00654, glgA, glycogen synthase GlgA.	0
NZ_CP045931.1\|WP_044811956.1\|1030658_1031105_-\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	3.29836e-15
NZ_CP045931.1\|WP_001162695.1\|1058786_1060490_-\|dihydrolipoyl-dehydrogenase	gnl\|CDD\|273568	TIGR01350, Dihydrolipoyl_dehydrogenase, dihydrolipoamide dehydrogenase. This model describes dihydrolipoamide dehydrogenase, a flavoprotein that acts in a number of ways. It is the E3 component of dehydrogenase complexes for pyruvate, 2-oxoglutarate, 2-oxoisovalerate, and acetoin. It can also serve as the L protein of the glycine cleavage system. This family includes a few members known to have distinct functions (ferric leghemoglobin reductase and NADH:ferredoxin oxidoreductase) but that may be predicted by homology to act as dihydrolipoamide dehydrogenase as well. The motif GGXCXXXGCXP near the N-terminus contains a redox-active disulfide.	0
NZ_CP045931.1\|WP_000448719.1\|1061796_1062789_-\|alpha-ketoacid-dehydrogenase-subunit-beta	gnl\|CDD\|223101	COG0022, AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion].	0
NZ_CP045931.1\|WP_000752697.1\|1060535_1061579_-\|dihydrolipoamide-acetyltransferase	gnl\|CDD\|184847	PRK14843, PRK14843, dihydrolipoamide acetyltransferase; Provisional.	0
NZ_CP045931.1\|WP_000417164.1\|1040887_1047313_+\|YSIRK-type-signal-peptide-containing-protein	gnl\|CDD\|369436	pfam07580, Peptidase_M26_C, M26 IgA1-specific Metallo-endopeptidase C-terminal region. These peptidases, which cleave mammalian IgA, are found in Gram-positive bacteria. Often found associated with pfam00746, they may be attached to the cell wall.	0
NZ_CP045931.1\|WP_000817884.1\|1056590_1057661_+\|tyrosine-recombinase-XerS	gnl\|CDD\|235339	PRK05084, xerS, site-specific tyrosine recombinase XerS; Reviewed.	0
NZ_CP045931.1\|WP_000201315.1\|1052823_1053675_+\|ribosome-biogenesis-GTPase-YlqF	gnl\|CDD\|236570	PRK09563, rbgA, GTPase YlqF; Reviewed.	4.3019e-158
NZ_CP045931.1\|WP_000772331.1\|1032363_1035639_+\|ATP-dependent-nuclease-subunit-B	gnl\|CDD\|274291	TIGR02774, putative_ATP-dependent_exonuclease_subunit_B, ATP-dependent nuclease subunit B. DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RecAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. The partner may be designated AddB, as in Bacillus and in alphaproteobacteria, or RexB as in Streptococcus and Lactococcus. Note, however, that RexB proteins lack an N-terminal GxxGxGK[ST] ATP-binding motif found in Bacillus subtilis and related species, and this difference may be important; this model represents specifically RexB proteins as found in Streptococcus and Lactococcus. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP045931.1\|WP_000687033.1\|1024524_1025664_+\|glucose-1-phosphate-adenylyltransferase-subunit-GlgD	gnl\|CDD\|273966	TIGR02092, Glycogen_biosynthesis_protein_GlgD, glucose-1-phosphate adenylyltransferase, GlgD subunit. This family is GlgD, an apparent regulatory protein that appears in an alpha2/beta2 heterotetramer with GlgC (glucose-1-phosphate adenylyltransferase, TIGR02091) in a subset of bacteria that use GlgC for glycogen biosynthesis. [Energy metabolism, Biosynthesis and degradation of polysaccharides].	0
NZ_CP045931.1\|WP_000105363.1\|1062804_1063773_-\|thiamine-pyrophosphate-dependent-dehydrogenase-E1-component-subunit-alpha	gnl\|CDD\|223997	COG1071, AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion].	3.2125e-157

>NZ_CP045931.1|WP_000417164.1|1040887_1047313_+|YSIRK-type-signal-peptide-containing-protein
MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQETAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSKNERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLLNYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDYNVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQLAEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYRDETIETKIDFQEEIQENPDLAEGTVRVKQEGALGKKVEIVRIFSVNNEEVSREIISTSTTAPVSRIVEKGTKKAQVIKEQAETGAEHKEVQSGAIVEPAIQPELPAAVLTDKGESAVQPELPEAVVSDKGVPEVQPALPEAVMTDKGDPEQVEPLPEYTGVQAGAIVEPEQVAPLPEYTGVQAGAIVEPEKVEAPKEYTGVQAGAIVEPEKVEAPKEYTGVQAGAIVEPEKVEPSKEYTGVQAGAIVEPEQIAPLPEYTGVQAGAIVEPEKVEALKEYTGKIEQPSAEDTKPNNENTNTPEEMSIQKKSSALINMNFITDSSKVTGVGSATFIAPNVLLTVAHNFINNSTDNTTGEFRGDKSKNVYEWVTPDGQKGTFTANNIHFYNKKDYPKGFIYDLAVIKLPETTGREHVELVKNYSKVNLNDKLNVHGYPAGKYTHLKDATVEMEQEYANNTYGVQYQGGNPGMSGGGIFNANGEVIGVHQNGAQNRSGGLILSPTQLAWIKSIIAGNEIPPVYDELYRHKDEKKDDAKDEKEVIKKLELRNISSVELYSKDGNKYRHVTSLASLPSNAENYFMKVKSENFKDVMLPVTSITNDTKDNRDVYKIVASANSLIQHENNNVLENYTYYLPKTQQSETGVYTSFKNLVDAMNSNPNGTFRLGATMDAREVELPDGQESYVNNVFHGILVGTNNEKYYAIYNLKKPLFGELNGATVEKLSLKDVNISAKDDTATLAKEANNNTHIDNVHADGAIAGERSIGGLVSQVNNSTISNSSYTGRITNTYKTVASYQIGGLVGKLSGPRGLIDKSFASIDLSSNATQGDQSIGGIVGAVENSALISNSYAEGNLNNVQRFANVGGVVGNLWDPVGGLEKSGRLSNVLSDVNVTNGNAIAGYNFNGIKANGTYSNKNNKVVNVVQEDDEILTKDSTVQRGEVLEDAQIKEKKATFVSKNTIKTEDFNFSSRYVTDYKNLENADSSKEKVYKNIEKLLPFYNRETIVKYGNLVETSSNLYNKELLSVVPMKDKEVISDINKNKSSINKLLLYYADNTSETLNVNYQTDFSNVAEYRIGGTNLIYTPNTLLRNYQNILDEVLPALNSVEYKSEAIRKVLDVSKDVSLTELYLEEQFNTTKTNLKDSLTKLLTADAAIAENNNKVIDNYVIEKIKNNKEALLLGLTYLERWYDFKYRDTKAKDLVMYHLDFFGKSNSSALDNVIELGKSGYNNLLAKNNVITYNVLLAKNYKTNNLFDALEKYRKAFVPDKTNNEWFKEQTKAYIVEEKSTIKEVSDKQSIAGSPYSIGVYDRLTSPSWKYPSMVLPLLTLPEKSVFIIANISTIGFGAYDRYRSKEHPAGTDLNDYVEKKAKEAAVRFRDHYDYWYRILDDKNKEKLYRSVLVYDAFRFGTDEKEDKDTYQATFETNHPAIKHFFGPAGNNVVHNSNGAYATGDAFYYMAYRMLDKDGAVTYTHEMTHNSDREIYLGGYGRRNGLGPEFYAKGLLQAPDHPNDPTVTINSILKYDQSEESTRLQVADPTQRFGSVDDLNKYMHNMFDVIYMLEILEGKAVAKLDTNQKYDLLRKIENEYKPDPDGNSVYATNVVRRLKPEELTKLTTFNSLIEHDIITRRGYVDEATYKRNGYYTINLFSPIYSALSSKIGTPGDLMGRRIAFELLAAKGYKDGMVPYISNQYEKEAKAQGKVITSYGKQIGLVTDEIVLSKVFNNQYNSWIDFKKDMYKEREDKFGKLNKVSFIDPNGSWARQQKVTIDNINRLEKMIEDAVKFDAEDEVAKLYPETNSRVLKLKKAIFKAYLDQTGDFRSSIFENKK
>NZ_CP045931.1|WP_000174775.1|1039500_1040679_+|hypothetical-protein
MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNCVCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKAQKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEPKKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAKQYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELEKDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDHLIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
>NZ_CP045931.1|WP_000767259.1|1035635_1039286_+|helicase-exonuclease-AddAB-subunit-AddA
MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNILVSASAGSGKTFVMVERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQETDDVDLKQHLGCQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLENEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWLSESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLILDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQFTKLGQLSDQITILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADISHYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQSIYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVGEINYDNMHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEILKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLDTLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMASSQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPARQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIHKSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIKLSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEVKQYPAAKNGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQDSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGVEIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLKQVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVRGILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLILLGKDEVQVVKV
>NZ_CP045931.1|WP_000772331.1|1032363_1035639_+|ATP-dependent-nuclease-subunit-B
MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKERAVLECLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDLRVYGAIKQDPQLIQQLIELYHEMTKSQMNFLDLENLTDEDKRADLLLIFEKVTAYLNQGQLAQGSQLSHLIEAIENDKVSSDFNQIALVIDGFTRFSAEEERVVDLLHGKGAEIVIGAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLESSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILLGDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLLRTDLYIDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAPLETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVLEQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYAIGLTQDNLPKISQNTSLLTDEERKNLNQTTEEGVQLLIASSENLKKNRYTMLSLVNSARKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSLVAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALYPAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQLPNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIETIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPHFFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKYQGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYTENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREELNR
>NZ_CP045931.1|WP_044811956.1|1030658_1031105_-|tyrosine-type-recombinase/integrase
MRKHGLISKSTSKGYYQVAIPFMRLFCLVLVSIDYINCLSETTDKNWHKSDRIFVTNTGKPVHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSENKIPLKTITDRVGHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF
>NZ_CP045931.1|WP_000022813.1|1029216_1030521_+|phosphopyruvate-hydratase
MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPIAFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDGVETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQIDYLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQEGAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK
>NZ_CP045931.1|WP_000131080.1|1028606_1029053_-|YueI-family-protein
MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTANSPQLEKGFLFILENLQEKAKPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHITSPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS
>NZ_CP045931.1|WP_078101594.1|1027794_1028610_+|glycerate-kinase
MRENMKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDGGEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKRNPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLCAFAQASIVSGIDTCLDLINFDKKVSDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAVFSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI
>NZ_CP045931.1|WP_000697290.1|1025660_1027094_+|glycogen-synthase-GlgA
MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYYDMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDFDDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYCWIQAYEDIETVLTIHNLEFQGQFSEGMLGDLFGVGLERYADGTLRWNNCLNWMKAGILYANRVSTVSPSYAHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAKNKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPAFEGAFSWFAQIYPDKLSANITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGTLPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNLQKQAMESDFSWDTACKSYLDLYHSLVN
>NZ_CP045931.1|WP_000687033.1|1024524_1025664_+|glucose-1-phosphate-adenylyltransferase-subunit-GlgD
MKIDKYSAILGNTVGFHDMSTLTDHRPVASLPFGGKYRLIDFPLSSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGKEYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDISEVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEKLRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTKVKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVIGEGAQVEYAILDKGVEVELGVVIRGTAEHPVVVKKGAKVTEDIHS
>NZ_CP045931.1|WP_000201315.1|1052823_1053675_+|ribosome-biogenesis-GTPase-YlqF
MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPMLTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAKKLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQWLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHYPEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTLEDLDGND
>NZ_CP045931.1|WP_000201099.1|1053661_1054441_+|ribonuclease-HII
MATIKEIKEFLVTVKELESPIFLELEKDNRSGVQKEISKRKRAIQAELDENLRLESMLSYEKELYKQGLTLIVGIDEVGRGPLAGPVVAAAVILPKNCKIKGLNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSPQPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDFATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES
>NZ_CP045931.1|WP_000392544.1|1054456_1056007_+|ClC-family-H(+)/Cl(-)-exchange-transporter
MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRFLIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAELKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEERSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFGLTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDRAYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYGSGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLTAMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTLIEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEIGKVKDLLL
>NZ_CP045931.1|WP_000817884.1|1056590_1057661_+|tyrosine-recombinase-XerS
MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKEYDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVSQTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQKLFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLDLRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLYRGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHASTQVTDLYTHIVSDEQKNALDSL
>NZ_CP045931.1|WP_000873991.1|1057733_1058723_-|lipoate--protein-ligase
MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVGRHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFSTPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLANALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFSEEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIYGDFFGIEDVAAVEAVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG
>NZ_CP045931.1|WP_001162695.1|1058786_1060490_-|dihydrolipoyl-dehydrogenase
MALEIIMPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEAEEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKSDDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHSAEIIENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVAVHKGIGTITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLVIIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDVEVSKNLRLILERKGMTILTGTKLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYMETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVAAVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPAAAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK
>NZ_CP045931.1|WP_000752697.1|1060535_1061579_-|dihydrolipoamide-acetyltransferase
MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYKDTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQIEKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRKKVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVGMDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQSFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKDLKELIETPISMLI
>NZ_CP045931.1|WP_000448719.1|1061796_1062789_-|alpha-ketoacid-dehydrogenase-subunit-beta
METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSVGMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAKTRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLLKSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRRVVQAAEELAEEEISVEIVDPRTLVPLDKDIIINSVKKTGKVILVNDAHKTSGYIGEISAIISESEAFDYLDAPIRRCSGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKD
>NZ_CP045931.1|WP_000105363.1|1062804_1063773_-|thiamine-pyrophosphate-dependent-dehydrogenase-E1-component-subunit-alpha
MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVGEEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMHIADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNMASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEGFQKAVDHVRSGNGSVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLIENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD
>NZ_CP045931.1|WP_000278526.1|1063926_1065288_-|sodium-coupled-multidrug-efflux-MATE-transporter-PdrM
MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNTMDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLSVVLLGMVLFLAPIILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLTKLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQEKLKALHLEKRIPLNMDNIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASHQSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTFLYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYLGLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAKSKR

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Crispr_ID: NZ_CP045931_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045931_3

1393627-1393763

Orphan

Consensus_repeat	Method
ACTTCTGGTGTCGGTACATTTGGTGTTGG	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP045931_3

>merge|NZ_CP045931|3|1393627-1393763|CRISPRCasFinder
ACTGGTTTAACCGGTACTTCTGGTGTTGGAACAGCTGGAGTTGGTTGTACTGGCACTTCTGGTGTCGGTACATTTGGTGTTGGTTGCGCTGGCACAGGTTTAACCGGTACTTCTGGTGTCGGCACATTTGGTGTTGG

>NZ_CP045931|3|3|1393627-1393763|CRISPRCasFinder
ACTGGTTTAACCGGTACTTCTGGTGTTGG	AACAGCTGGAGTTGGTTGTACTGGC
ACTTCTGGTGTCGGTACATTTGGTGTTGG	TTGCGCTGGCACAGGTTTAACCGGT
ACTTCTGGTGTCGGCACATTTGGTGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045931.1\|WP_001151785.1\|1388480_1388771_-\|30S-ribosomal-protein-S6	unknown	unknown	gnl\|CDD\|179034
NZ_CP045931.1\|WP_001838303.1\|1412194_1413394_-\|CCA-tRNA-nucleotidyltransferase	unknown	unknown	gnl\|CDD\|237339
NZ_CP045931.1\|WP_000565216.1\|1390426_1390651_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|319923
NZ_CP045931.1\|WP_000412224.1\|1404669_1405080_-\|peptide-deformylase	unknown	unknown	gnl\|CDD\|181704
NZ_CP045931.1\|WP_000777778.1\|1390643_1391831_-\|pyridoxal-phosphate-dependent-aminotransferase	unknown	unknown	gnl\|CDD\|235596
NZ_CP045931.1\|WP_000339026.1\|1386032_1387433_-\|bifunctional-Cof-type-HAD-IIB-family-hydrolase/peptidylprolyl-isomerase	unknown	unknown	gnl\|CDD\|223725
NZ_CP045931.1\|WP_000032465.1\|1405999_1408696_-\|cation-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319781
NZ_CP045931.1\|WP_000153791.1\|1391827_1392259_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227656
NZ_CP045931.1\|WP_001279158.1\|1410326_1412198_-\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|223562
NZ_CP045931.1\|WP_001106143.1\|1400365_1401874_+\|HTH-domain-containing-protein	unknown	unknown	gnl\|CDD\|285470
NZ_CP045931.1\|WP_000039618.1\|1392636_1393185_+\|NAD(P)H-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|223508
NZ_CP045931.1\|WP_000813910.1\|1408999_1410184_+\|CDF-family-manganese-efflux-transporter-MntE	unknown	unknown	gnl\|CDD\|223131
NZ_CP045931.1\|WP_000697775.1\|1401924_1402653_-\|peroxide-stress-protein-YaaA	unknown	unknown	gnl\|CDD\|234999
NZ_CP045931.1\|WP_000822876.1\|1403062_1404658_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045931.1\|WP_001277403.1\|1405195_1405987_-\|glutathione-dependent-disulfide-bond-oxidoreductase	unknown	unknown	gnl\|CDD\|183298
NZ_CP045931.1\|WP_000389568.1\|1402731_1402911_-\|DUF3953-domain-containing-protein	unknown	unknown	gnl\|CDD\|315732
NZ_CP045931.1\|WP_000167152.1\|1388923_1390267_-\|asparagine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235176
NZ_CP045931.1\|WP_000689596.1\|1385671_1386031_-\|S1-RNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|180908
NZ_CP045931.1\|WP_000609605.1\|1387998_1388469_-\|single-stranded-DNA-binding-protein	unknown	unknown	gnl\|CDD\|180915
NZ_CP045931.1\|WP_000068664.1\|1387727_1387967_-\|30S-ribosomal-protein-S18	unknown	unknown	gnl\|CDD\|178997

Protein	Function_ID	Function_description	E-value
NZ_CP045931.1\|WP_001151785.1\|1388480_1388771_-\|30S-ribosomal-protein-S6	gnl\|CDD\|179034	PRK00453, rpsF, 30S ribosomal protein S6; Reviewed.	1.40041e-37
NZ_CP045931.1\|WP_001838303.1\|1412194_1413394_-\|CCA-tRNA-nucleotidyltransferase	gnl\|CDD\|237339	PRK13299, PRK13299, tRNA CCA-pyrophosphorylase; Provisional.	0
NZ_CP045931.1\|WP_000565216.1\|1390426_1390651_-\|hypothetical-protein	gnl\|CDD\|319923	cd07262, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	1.22811e-09
NZ_CP045931.1\|WP_000412224.1\|1404669_1405080_-\|peptide-deformylase	gnl\|CDD\|181704	PRK09218, PRK09218, peptide deformylase; Validated.	7.64356e-90
NZ_CP045931.1\|WP_000777778.1\|1390643_1391831_-\|pyridoxal-phosphate-dependent-aminotransferase	gnl\|CDD\|235596	PRK05764, PRK05764, aspartate aminotransferase; Provisional.	0
NZ_CP045931.1\|WP_000339026.1\|1386032_1387433_-\|bifunctional-Cof-type-HAD-IIB-family-hydrolase/peptidylprolyl-isomerase	gnl\|CDD\|223725	COG0652, PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family [Posttranslational modification, protein turnover, chaperones].	1.16397e-60
NZ_CP045931.1\|WP_000032465.1\|1405999_1408696_-\|cation-translocating-P-type-ATPase	gnl\|CDD\|319781	cd02089, P-type_ATPase_Ca_prok, prokaryotic P-type Ca(2+)-ATPase similar to Synechococcus elongatus sp. strain PCC 7942 PacL and Listeria monocytogenes LMCA1. Ca(2+) transport ATPase is a plasma membrane protein which pumps Ca(2+) ion out of the cytoplasm. This prokaryotic subfamily includes the Ca(2+)-ATPase Synechococcus elongatus PacL, Listeria monocytogenes Ca(2+)-ATPase 1 (LMCA1) which has a low Ca(2+) affinity and a high pH optimum (pH about 9) and may remove Ca(2+) from the microorganism in environmental conditions when e.g. stressed by high Ca(2+) and alkaline pH, and the Bacillus subtilis putative P-type Ca(2+)-transport ATPase encoded by the yloB gene, which is expressed during sporulation. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_CP045931.1\|WP_000153791.1\|1391827_1392259_-\|hypothetical-protein	gnl\|CDD\|227656	COG5353, COG5353, Uncharacterized protein conserved in bacteria [Function unknown].	1.44816e-57
NZ_CP045931.1\|WP_001279158.1\|1410326_1412198_-\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	0
NZ_CP045931.1\|WP_001106143.1\|1400365_1401874_+\|HTH-domain-containing-protein	gnl\|CDD\|285470	pfam08270, PRD_Mga, M protein trans-acting positive regulator (MGA) PRD domain. Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. This corresponds to the PRD like region.	4.98387e-77
NZ_CP045931.1\|WP_000039618.1\|1392636_1393185_+\|NAD(P)H-dependent-oxidoreductase	gnl\|CDD\|223508	COG0431, COG0431, Predicted flavoprotein [General function prediction only].	1.06789e-32
NZ_CP045931.1\|WP_000697775.1\|1401924_1402653_-\|peroxide-stress-protein-YaaA	gnl\|CDD\|234999	PRK02101, PRK02101, peroxide stress protein YaaA.	5.15942e-96
NZ_CP045931.1\|WP_000813910.1\|1408999_1410184_+\|CDF-family-manganese-efflux-transporter-MntE	gnl\|CDD\|223131	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism].	2.47934e-101
NZ_CP045931.1\|WP_001277403.1\|1405195_1405987_-\|glutathione-dependent-disulfide-bond-oxidoreductase	gnl\|CDD\|183298	PRK11752, PRK11752, putative S-transferase; Provisional.	0
NZ_CP045931.1\|WP_000389568.1\|1402731_1402911_-\|DUF3953-domain-containing-protein	gnl\|CDD\|315732	pfam13129, DUF3953, Protein of unknown function (DUF3953). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 47 and 76 amino acids in length.	7.99728e-05
NZ_CP045931.1\|WP_000167152.1\|1388923_1390267_-\|asparagine--tRNA-ligase	gnl\|CDD\|235176	PRK03932, asnC, asparaginyl-tRNA synthetase; Validated.	0
NZ_CP045931.1\|WP_000689596.1\|1385671_1386031_-\|S1-RNA-binding-domain-containing-protein	gnl\|CDD\|180908	PRK07252, PRK07252, S1 RNA-binding domain-containing protein.	7.1116e-79
NZ_CP045931.1\|WP_000609605.1\|1387998_1388469_-\|single-stranded-DNA-binding-protein	gnl\|CDD\|180915	PRK07275, PRK07275, single-stranded DNA-binding protein; Provisional.	3.47122e-100
NZ_CP045931.1\|WP_000068664.1\|1387727_1387967_-\|30S-ribosomal-protein-S18	gnl\|CDD\|178997	PRK00391, rpsR, 30S ribosomal protein S18; Reviewed.	3.32721e-37

>NZ_CP045931.1|WP_000039618.1|1392636_1393185_+|NAD(P)H-dependent-oxidoreductase
MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALPLFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDTRGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKLVLEETVLNSLEKQAQDLVEAIQ
>NZ_CP045931.1|WP_000153791.1|1391827_1392259_-|hypothetical-protein
MTILFVVISASFLYMVSLSMKPYQTAKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQLNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKEGL
>NZ_CP045931.1|WP_000777778.1|1390643_1391831_-|pyridoxal-phosphate-dependent-aminotransferase
MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTTPKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKYSLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAARTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTPISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQYAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAMEMKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGSEND
>NZ_CP045931.1|WP_000565216.1|1390426_1390651_-|hypothetical-protein
MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPNSPHPGGDFWLTQGTQDPVHFAFLAENKEEV
>NZ_CP045931.1|WP_000167152.1|1388923_1390267_-|asparagine--tRNA-ligase
MTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTAFFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITDIEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGFMKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRAEKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTELLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPTFVMNYPVAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDELGMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP
>NZ_CP045931.1|WP_001151785.1|1388480_1388771_-|30S-ribosomal-protein-S6
MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWEKRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA
>NZ_CP045931.1|WP_000609605.1|1387998_1388469_-|single-stranded-DNA-binding-protein
MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGEREADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQMLESRSVREGHTGGAYSAPTANYSAPTNSVLDFSRNENPFGATNPLDISDDDLPF
>NZ_CP045931.1|WP_000068664.1|1387727_1387967_-|30S-ribosomal-protein-S18
MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKILPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED
>NZ_CP045931.1|WP_000339026.1|1386032_1387433_-|bifunctional-Cof-type-HAD-IIB-family-hydrolase/peptidylprolyl-isomerase
MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLREKGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYISWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFEDKGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDGLNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQVDIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMIQGGNPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLPYSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAMDKPVEDVVIETIEIED
>NZ_CP045931.1|WP_000689596.1|1385671_1386031_-|S1-RNA-binding-domain-containing-protein
MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENIHETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRRMLPIWTGEALHHLKKKK
>NZ_CP045931.1|WP_001106143.1|1400365_1401874_+|HTH-domain-containing-protein
MNYGGNTRMRNLLSTKVQRQLRLMETLIQNRNWMKLHELAEKLGCTERILKSDLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLPIYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSERYYFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFIDLPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEFFNSLEDNSQARYSYQLLSQILERLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPILFEQKALTIKKFEVYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLSTQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDYDIIVSNFYIPGITKKFICRNHLSIMNLVNHLNTLSNEIHLSNTL
>NZ_CP045931.1|WP_000697775.1|1401924_1402653_-|peroxide-stress-protein-YaaA
MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLESFYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHVFITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSSEFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARRLNFAGFVYREDLSQPQGLVFVKEV
>NZ_CP045931.1|WP_000389568.1|1402731_1402911_-|DUF3953-domain-containing-protein
MEDKEMGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALVLVAVWLGWPK
>NZ_CP045931.1|WP_000822876.1|1403062_1404658_-|hypothetical-protein
MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILFGFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSMFQAKNYANVVTVTEKDFTEFPRSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAADTYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYSDSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVIILDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTNGYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEGAVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEMLSKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPYLENGKTFEGQVGKDNYLKTFKVQ
>NZ_CP045931.1|WP_000412224.1|1404669_1405080_-|peptide-deformylase
MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGLAANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETTRLAYRDSKWQEQTITLTGFPAQICQHELDHLEGRII
>NZ_CP045931.1|WP_001277403.1|1405195_1405987_-|glutathione-dependent-disulfide-bond-oxidoreductase
MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQLYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPALLDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFGHFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLVQGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK
>NZ_CP045931.1|WP_000032465.1|1405999_1408696_-|cation-translocating-P-type-ATPase
MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHNELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAFGVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLRLLEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVVNTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALITFVVGVFIQGKNPLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIASDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIGDPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGAPDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLTSEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGIIDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAMTGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNIQKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGVMNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALTMAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGIFHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI
>NZ_CP045931.1|WP_000813910.1|1408999_1410184_+|CDF-family-manganese-efflux-transporter-MntE
MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVADGFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDILRDTIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDAVTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLEDYQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERFGVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQMDKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETKKE
>NZ_CP045931.1|WP_001279158.1|1410326_1412198_-|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTTLLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIREYELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGLRRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDALSTRIFELERAGLTEYQGNYQDYVRLKAEQDERDATLLHKKEQLYKQELAWMRRQPQARATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQDVSFAYENKPILQDFNLLVQVKDRIGIVGDNGVGKSTLLNLIAGSLEPIAGQVVIGETVRIAYFSQQIEGLDESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLLKLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAFEDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASIEGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS
>NZ_CP045931.1|WP_001838303.1|1412194_1413394_-|CCA-tRNA-nucleotidyltransferase
MRLTQMPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIATSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVRSLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMRGFRFQASLGFALEPETFKAMKTLTPLLENISVERTFVEFDKLLLAPFWRRGLASMIESQAYDYLPDMASSQNKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSRQFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQARGKEVNPQAITEKYQSLTIHDKKEIQINGDILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLREKK

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Crispr_ID: NZ_CP045931_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045931_4

1527733-1527821

Unclear

Consensus_repeat	Method
GCTGGCTCTTCACCGGATGTCCCTAATGG	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of NZ_CP045931_4

>merge|NZ_CP045931|4|1527733-1527821|CRISPRCasFinder
GCTGGCTCTTCACCGGATGTCCCTAATGGACCTGTATATTCTGGCTTCTCTACTGTCGGGGCTGGCTCTTCGCCGGATGTCCCTAATGG

>NZ_CP045931|4|4|1527733-1527821|CRISPRCasFinder
GCTGGCTCTTCACCGGATGTCCCTAATGG	ACCTGTATATTCTGGCTTCTCTACTGTCGGG
GCTGGCTCTTCGCCGGATGTCCCTAATGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045931.1\|WP_000648087.1\|1535132_1536236_-\|alanine-racemase	unknown	unknown	gnl\|CDD\|234600
NZ_CP045931.1\|WP_073078479.1\|1541436_1541664_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045931.1\|WP_001274093.1\|1538777_1541291_-\|preprotein-translocase-subunit-SecA	unknown	unknown	gnl\|CDD\|237259
NZ_CP045931.1\|WP_001235285.1\|1541734_1542385_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|213197
NZ_CP045931.1\|WP_001242366.1\|1536225_1536594_-\|holo-ACP-synthase	unknown	unknown	gnl\|CDD\|234610
NZ_CP045931.1\|WP_001135651.1\|1518763_1519462_-\|N-acetylmannosamine-6-phosphate-2-epimerase	unknown	unknown	gnl\|CDD\|234907
NZ_CP045931.1\|WP_001808374.1\|1514656_1515553_-\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224096
NZ_CP045931.1\|WP_000738763.1\|1524658_1525996_-\|sugar-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270303
NZ_CP045931.1\|WP_000576349.1\|1530769_1530997_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045931.1\|WP_000237988.1\|1523695_1524580_-\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224096
NZ_CP045931.1\|WP_000232209.1\|1537665_1538697_-\|3-deoxy-7-phosphoheptulonate-synthase	unknown	unknown	gnl\|CDD\|223794
NZ_CP045931.1\|WP_042515862.1\|1520751_1522845_-\|neuraminidase-NanB	unknown	unknown	gnl\|CDD\|226840
NZ_CP045931.1\|WP_000672121.1\|1515774_1517103_-\|carbohydrate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224567
NZ_CP045931.1\|WP_073177152.1\|1517227_1518760_-\|PTS-glucose-transporter-subunit-IIBC	unknown	unknown	gnl\|CDD\|273923
NZ_CP045931.1\|WP_000587470.1\|1526014_1526467_-\|YhcH/YjgK/YiaL-family-protein	unknown	unknown	gnl\|CDD\|129133
NZ_CP045931.1\|WP_000730476.1\|1522862_1523696_-\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472
NZ_CP045931.1\|WP_000795139.1\|1531801_1532782_-\|acetylxylan-esterase	unknown	unknown	gnl\|CDD\|225989
NZ_CP045931.1\|WP_047474488.1\|1533098_1535114_-\|ATP-dependent-DNA-helicase-RecG	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|236794
NZ_CP045931.1\|WP_000864060.1\|1536632_1537664_-\|3-deoxy-7-phosphoheptulonate-synthase	unknown	unknown	gnl\|CDD\|223794
NZ_CP045931.1\|WP_000241719.1\|1519635_1520739_-\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745

Protein	Function_ID	Function_description	E-value
NZ_CP045931.1\|WP_000648087.1\|1535132_1536236_-\|alanine-racemase	gnl\|CDD\|234600	PRK00053, alr, alanine racemase; Reviewed.	1.99862e-165
NZ_CP045931.1\|WP_001274093.1\|1538777_1541291_-\|preprotein-translocase-subunit-SecA	gnl\|CDD\|237259	PRK12904, PRK12904, preprotein translocase subunit SecA; Reviewed.	0
NZ_CP045931.1\|WP_001235285.1\|1541734_1542385_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|213197	cd03230, ABC_DR_subfamily_A, ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A. This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	6.38164e-54
NZ_CP045931.1\|WP_001242366.1\|1536225_1536594_-\|holo-ACP-synthase	gnl\|CDD\|234610	PRK00070, acpS, 4'-phosphopantetheinyl transferase; Provisional.	6.25088e-46
NZ_CP045931.1\|WP_001135651.1\|1518763_1519462_-\|N-acetylmannosamine-6-phosphate-2-epimerase	gnl\|CDD\|234907	PRK01130, PRK01130, putative N-acetylmannosamine-6-phosphate 2-epimerase.	6.59929e-124
NZ_CP045931.1\|WP_001808374.1\|1514656_1515553_-\|sugar-ABC-transporter-permease	gnl\|CDD\|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	4.63174e-80
NZ_CP045931.1\|WP_000738763.1\|1524658_1525996_-\|sugar-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270303	cd13585, PBP2_TMBP_like, The periplasmic-binding component of ABC transport systems specific for trehalose/maltose and similar oligosaccharides; possess type 2 periplasmic binding fold. This family includes the periplasmic trehalose/maltose-binding component of an ABC transport system and related proteins from archaea and bacteria. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	6.1555e-69
NZ_CP045931.1\|WP_000237988.1\|1523695_1524580_-\|sugar-ABC-transporter-permease	gnl\|CDD\|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	7.22876e-85
NZ_CP045931.1\|WP_000232209.1\|1537665_1538697_-\|3-deoxy-7-phosphoheptulonate-synthase	gnl\|CDD\|223794	COG0722, AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase [Amino acid transport and metabolism].	0
NZ_CP045931.1\|WP_042515862.1\|1520751_1522845_-\|neuraminidase-NanB	gnl\|CDD\|226840	COG4409, NanH, Neuraminidase (sialidase) [Carbohydrate transport and metabolism].	0
NZ_CP045931.1\|WP_000672121.1\|1515774_1517103_-\|carbohydrate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224567	COG1653, UgpB, ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism].	1.30995e-51
NZ_CP045931.1\|WP_073177152.1\|1517227_1518760_-\|PTS-glucose-transporter-subunit-IIBC	gnl\|CDD\|273923	TIGR02002, PTS_system_glucose-specific_IIABC_component, PTS system, glucose-specific IIBC component. This model represents the combined B and C domains of the PTS transport system enzyme II specific for glucose transport. Many of the genes in this family also include an A domain as part of the same polypeptide and thus should be given the name "PTS system, glucose-specific IIABC component" while the B. subtilus enzyme also contains an enzyme III domain which appears to act independently of the enzyme II domains. This family is most closely related to the N-acetylglucosamine-specific PTS enzymes (TIGR01998). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	5.60402e-159
NZ_CP045931.1\|WP_000587470.1\|1526014_1526467_-\|YhcH/YjgK/YiaL-family-protein	gnl\|CDD\|129133	TIGR00022, Uncharacterized_protein_HI_0227, YhcH/YjgK/YiaL family protein. This family consists of conserved hypothetical proteins, about 150 amino acids in length. Members with limited information include YhcH, a possible sugar isomerase of sialic acid catabolism, and YjgK. [Unknown function, General].	3.28513e-66
NZ_CP045931.1\|WP_000730476.1\|1522862_1523696_-\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	1.74183e-77
NZ_CP045931.1\|WP_000795139.1\|1531801_1532782_-\|acetylxylan-esterase	gnl\|CDD\|225989	COG3458, COG3458, Acetyl esterase (deacetylase) [Secondary metabolites biosynthesis, transport, and catabolism].	4.13556e-171
NZ_CP045931.1\|WP_047474488.1\|1533098_1535114_-\|ATP-dependent-DNA-helicase-RecG	gnl\|CDD\|236794	PRK10917, PRK10917, ATP-dependent DNA helicase RecG; Provisional.	0
NZ_CP045931.1\|WP_000864060.1\|1536632_1537664_-\|3-deoxy-7-phosphoheptulonate-synthase	gnl\|CDD\|223794	COG0722, AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase [Amino acid transport and metabolism].	0
NZ_CP045931.1\|WP_000241719.1\|1519635_1520739_-\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	4.15803e-71

>NZ_CP045931.1|WP_000587470.1|1526014_1526467_-|YhcH/YjgK/YiaL-family-protein
MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGNRLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDIELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS
>NZ_CP045931.1|WP_000738763.1|1524658_1525996_-|sugar-ABC-transporter-substrate-binding-protein
MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEITMWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDISTALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWVRTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGGSLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNSGFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFLEALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTAIGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ
>NZ_CP045931.1|WP_000237988.1|1523695_1524580_-|sugar-ABC-transporter-permease
MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMPNYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLYRTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLVFINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVVLRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVAICFIYFAIISKWEKEGRK
>NZ_CP045931.1|WP_000730476.1|1522862_1523696_-|carbohydrate-ABC-transporter-permease
MKKKSSIYLDILSHVLLVGATIVAVFPLVWIIISSVKGKGELTQYPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFPKLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLVGFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALILINNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSVK
>NZ_CP045931.1|WP_042515862.1|1520751_1522845_-|neuraminidase-NanB
MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQGGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKADFKNNYFSIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMYVNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQEVSTIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKINIATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDKKSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVYDETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLREKHNGKQVPMNVFYKDSLFKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFATYTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYMTSRDSGETWSKVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQLVVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLSNVVQYIDLEINDLTK
>NZ_CP045931.1|WP_000241719.1|1519635_1520739_-|Gfo/Idh/MocA-family-oxidoreductase
MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEELGAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCREMVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSWKKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNMEFSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQEEDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKLLTGEAALEAIATADACTQSMFEDRKVKLSEIVK
>NZ_CP045931.1|WP_001135651.1|1518763_1519462_-|N-acetylmannosamine-6-phosphate-2-epimerase
MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAAEQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIEVIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTLSGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAITRPKEITERFVASLK
>NZ_CP045931.1|WP_073177152.1|1517227_1518760_-|PTS-glucose-transporter-subunit-IIBC
MRGSFMFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPILDNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATIKALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTSFSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPMFWYTELGGVETVAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAACLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVSFFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFITQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVTRLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD
>NZ_CP045931.1|WP_000672121.1|1515774_1517103_-|carbohydrate-ABC-transporter-substrate-binding-protein
MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEITWWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGTAPDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISSAPFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGTRAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNFANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKDDKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSPYYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ
>NZ_CP045931.1|WP_001808374.1|1514656_1515553_-|sugar-ABC-transporter-permease
MPTVKVNKIRMRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEFVGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFVFFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIILLTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITTINSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSFVQFKVLGNDVEY
>NZ_CP045931.1|WP_000576349.1|1530769_1530997_-|hypothetical-protein
MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLDKILIVSLIIFPIISTSIYAYEKLFEKVFDKD
>NZ_CP045931.1|WP_000795139.1|1531801_1532782_-|acetylxylan-esterase
MKNPALLEEIKTYRGRDEVPEDFDDFWDGEVKNVSTLPSYHLEERDFHIPQVKCYELTFEGSKKGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGFTVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAVEGRDHLFYKDVYLDIYQLVEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGNTSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYPITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK
>NZ_CP045931.1|WP_047474488.1|1533098_1535114_-|ATP-dependent-DNA-helicase-RecG
MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFKTKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLADKIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFDQGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQLQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNRLLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLTGSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRILREKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVLTWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSDEKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRGDKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQVADIIEDFPILEEARKVASYISSIETWQEDPEWRMIALHLEKKEHLD
>NZ_CP045931.1|WP_000648087.1|1535132_1536236_-|alanine-racemase
MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKWAVVKANAYGHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFTLTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREVSEVEQAQDLLQKHGVCVEGIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVRMGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIATVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNGDKEITATQVATYRVTINYEVVCLLSDRIPREYY
>NZ_CP045931.1|WP_001242366.1|1536225_1536594_-|holo-ACP-synthase
MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLKGRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLSISHTDQFVTASVILEENHES
>NZ_CP045931.1|WP_000864060.1|1536632_1537664_-|3-deoxy-7-phosphoheptulonate-synthase
MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGEDDRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLVHQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGARSVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPLAHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQIRIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALVEEIYVTLTK
>NZ_CP045931.1|WP_000232209.1|1537665_1538697_-|3-deoxy-7-phosphoheptulonate-synthase
MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGEDQRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLIHQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGARSVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPLSHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQIRIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALVREIYKTLGE
>NZ_CP045931.1|WP_001274093.1|1538777_1541291_-|preprotein-translocase-subunit-SecA
MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAKTVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRTGEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKSPMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEARTPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLENLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGLHQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIPIPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKLVAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSEEAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYTQRYDVITADRDLAPEIQAMIKRTIGRVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAIKEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLRGYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRNIAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ
>NZ_CP045931.1|WP_073078479.1|1541436_1541664_-|hypothetical-protein
MIWLSFFFIPWDRAILGVRIDIFIIQKVLLVFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN
>NZ_CP045931.1|WP_001235285.1|1541734_1542385_-|ATP-binding-cassette-domain-containing-protein
MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVLLKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFSSKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNALDEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQYVKDIQS

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Crispr_ID: NZ_CP045931_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045931_5

1642673-1642757

Orphan

Consensus_repeat	Method
CTTTTTTTGAAACGTTTCATTTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP045931_5

>merge|NZ_CP045931|5|1642673-1642757|CRISPRCasFinder
CTTTTTTTGAAACGTTTCATTTTTTCTATAAAAGATAGCGCTTGGCGCTGTCTTTTTATTTCTTTTTTTGAAACGTTTCATTTTT

>NZ_CP045931|5|5|1642673-1642757|CRISPRCasFinder
CTTTTTTTGAAACGTTTCATTTTT	TCTATAAAAGATAGCGCTTGGCGCTGTCTTTTTATTT
CTTTTTTTGAAACGTTTCATTTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045931.1\|WP_000257084.1\|1633635_1634106_-\|DUF3013-family-protein	unknown	unknown	gnl\|CDD\|337951
NZ_CP045931.1\|WP_000797961.1\|1640844_1641735_-\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472
NZ_CP045931.1\|WP_000030213.1\|1646348_1646915_+\|alkaline-shock-response-membrane-anchor-protein-AmaP	unknown	unknown	gnl\|CDD\|380217
NZ_CP045931.1\|WP_000230202.1\|1642813_1643815_-\|LacI-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525
NZ_CP045931.1\|WP_001812322.1\|1648669_1648957_+\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_CP045931.1\|WP_001113208.1\|1636053_1637325_+\|replication-associated-recombination-protein-A	unknown	unknown	gnl\|CDD\|237355
NZ_CP045931.1\|WP_000344536.1\|1651163_1651481_-\|PTS-lactose/cellobiose-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|376749
NZ_CP045931.1\|WP_000669745.1\|1639199_1640816_-\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|270299
NZ_CP045931.1\|WP_000064115.1\|1647135_1647744_+\|Asp23/Gls24-family-envelope-stress-response-protein	unknown	unknown	gnl\|CDD\|224221
NZ_CP045931.1\|WP_000502548.1\|1637870_1639190_-\|glycoside-hydrolase-family-32-protein	unknown	unknown	gnl\|CDD\|224536
NZ_CP045931.1\|WP_075270891.1\|1632549_1633632_-\|site-2-protease-family-protein	unknown	unknown	gnl\|CDD\|308008
NZ_CP045931.1\|WP_075270892.1\|1634885_1635092_-\|type-II-toxin-antitoxin-system-HicA-family-toxin	unknown	unknown	gnl\|CDD\|377942
NZ_CP045931.1\|WP_001809903.1\|1635201_1635381_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045931.1\|WP_000961810.1\|1634396_1634849_-\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	unknown	unknown	gnl\|CDD\|224514
NZ_CP045931.1\|WP_001205280.1\|1644176_1645658_-\|aspartate-aminotransferase	unknown	unknown	gnl\|CDD\|285470
NZ_CP045931.1\|WP_000229335.1\|1649234_1650005_-\|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl\|CDD\|376667
NZ_CP045931.1\|WP_001820409.1\|1646100_1646265_+\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	unknown	unknown	gnl\|CDD\|225170
NZ_CP045931.1\|WP_001084979.1\|1641745_1642663_-\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226666
NZ_CP045931.1\|WP_000455066.1\|1646926_1647097_+\|DUF2273-domain-containing-protein	unknown	unknown	gnl\|CDD\|227834
NZ_CP045931.1\|WP_000109957.1\|1647774_1647978_+\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|225777

Protein	Function_ID	Function_description	E-value
NZ_CP045931.1\|WP_000257084.1\|1633635_1634106_-\|DUF3013-family-protein	gnl\|CDD\|337951	pfam11217, DUF3013, Protein of unknown function (DUF3013). This bacterial family of proteins with unknown function appear to be restricted to Firmicutes.	2.85966e-66
NZ_CP045931.1\|WP_000797961.1\|1640844_1641735_-\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	4.20755e-67
NZ_CP045931.1\|WP_000030213.1\|1646348_1646915_+\|alkaline-shock-response-membrane-anchor-protein-AmaP	gnl\|CDD\|380217	NF033218, anchor_AmaP, alkaline shock response membrane anchor protein AmaP. The founding member of this family, AmaP (Asp23 membrane anchoring protein), is related to Asp23 through part of its length, but includes a highly hydrophobic N-terminal region that should make it an integral membrane protein. Asp23 (alkaline shock protein of 23 kDa), described in PMID:7864904, is a cytosolic protein in Staphylococcus aureus, strongly induced by a pH shift from 7 to 10, and also recruited to the membrane. AmaP appears to be the partner protein with an integral membrane segment and the ability to anchor Asp23 to the membrane. This model was built to identify full-length homologs of AmaP, while excluding Asp23. Some but not all members of this family score above the cutoffs of Pfam model version PF03780.11, but full-length homologs of Asp23 score considerably higher. Asp23 family members previously were known as DUF322.	7.65552e-46
NZ_CP045931.1\|WP_000230202.1\|1642813_1643815_-\|LacI-family-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	6.78682e-99
NZ_CP045931.1\|WP_001113208.1\|1636053_1637325_+\|replication-associated-recombination-protein-A	gnl\|CDD\|237355	PRK13342, PRK13342, recombination factor protein RarA; Reviewed.	0
NZ_CP045931.1\|WP_000344536.1\|1651163_1651481_-\|PTS-lactose/cellobiose-transporter-subunit-IIA	gnl\|CDD\|376749	pfam02255, PTS_IIA, PTS system, Lactose/Cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. The lactose/cellobiose-specific family are one of four structurally and functionally distinct group IIA PTS system enzymes. This family of proteins normally function as a homotrimer, stabilized by a centrally located metal ion. Separation into subunits is thought to occur after phosphorylation.	7.84605e-40
NZ_CP045931.1\|WP_000669745.1\|1639199_1640816_-\|extracellular-solute-binding-protein	gnl\|CDD\|270299	cd13581, PBP2_AlgQ_like_2, Periplasmic-binding component of alginate-specific ABC uptake system-like; contains the type 2 periplasmic binding fold. This subgroup includes uncharacterized periplasmic-binding proteins that are closely related to high molecular weight (HMW) alginate bining proteins (AlgQ1 and AlgQ2) found in gram-negative soil bacteria. The HMW alginate uptake system is composed of a novel pit formed on the cell surface and a pit-dependent ATP-binding cassette (ABC) transporter in the inner membrane. The transportation of HMW alginate from the pit to the ABC transporter is mediated by periplasmic HMW alginate-binding proteins (AlgQ1 and AlgQ2). Alginate is an anionic polysaccharide that is made up of alpha-L-mannuronate and its 5'-epimer, alpha-L-guluronate. Alginate is present in the cell walls of brown seaweeds, where it forms a viscous gum by binding water. Alginate is also produced by two bacteria genera Pseudomonas and Azotobacter. AlgQ1 and AlgQ2 belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. However, unlike other bacterial periplasmic-binding proteins that deliver small solutes to ABC transporters, AlgQ1/2 can bind a macromolecule and may have specificity for either sugar or a certain type of polysaccharide.	0
NZ_CP045931.1\|WP_000064115.1\|1647135_1647744_+\|Asp23/Gls24-family-envelope-stress-response-protein	gnl\|CDD\|224221	COG1302, COG1302, Uncharacterized protein conserved in bacteria [Function unknown].	1.35166e-33
NZ_CP045931.1\|WP_000502548.1\|1637870_1639190_-\|glycoside-hydrolase-family-32-protein	gnl\|CDD\|224536	COG1621, SacC, Beta-fructosidases (levanase/invertase) [Carbohydrate transport and metabolism].	8.94192e-178
NZ_CP045931.1\|WP_075270891.1\|1632549_1633632_-\|site-2-protease-family-protein	gnl\|CDD\|308008	pfam02163, Peptidase_M50, Peptidase family M50.	7.5059e-06
NZ_CP045931.1\|WP_075270892.1\|1634885_1635092_-\|type-II-toxin-antitoxin-system-HicA-family-toxin	gnl\|CDD\|377942	pfam07927, HicA_toxin, HicA toxin of bacterial toxin-antitoxin,. HicA_toxin is a bacterial family of toxins that act as mRNA interferases. The antitoxin that neutralizes this is family HicB, pfam15919.	1.54317e-07
NZ_CP045931.1\|WP_001812322.1\|1648669_1648957_+\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	1.91273e-14
NZ_CP045931.1\|WP_000961810.1\|1634396_1634849_-\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	gnl\|CDD\|224514	COG1598, COG1598, Predicted nuclease of the RNAse H fold, HicB family [General function prediction only].	1.2282e-11
NZ_CP045931.1\|WP_001205280.1\|1644176_1645658_-\|aspartate-aminotransferase	gnl\|CDD\|285470	pfam08270, PRD_Mga, M protein trans-acting positive regulator (MGA) PRD domain. Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. This corresponds to the PRD like region.	1.09342e-73
NZ_CP045931.1\|WP_000229335.1\|1649234_1650005_-\|sulfite-exporter-TauE/SafE-family-protein	gnl\|CDD\|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	3.69751e-17
NZ_CP045931.1\|WP_001820409.1\|1646100_1646265_+\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	gnl\|CDD\|225170	COG2261, COG2261, Predicted membrane protein [Function unknown].	3.5793e-06
NZ_CP045931.1\|WP_001084979.1\|1641745_1642663_-\|sugar-ABC-transporter-permease	gnl\|CDD\|226666	COG4209, LplB, ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism].	1.73729e-138
NZ_CP045931.1\|WP_000455066.1\|1646926_1647097_+\|DUF2273-domain-containing-protein	gnl\|CDD\|227834	COG5547, COG5547, Small integral membrane protein [Function unknown].	9.45975e-16
NZ_CP045931.1\|WP_000109957.1\|1647774_1647978_+\|CsbD-family-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	1.20386e-07

>NZ_CP045931.1|WP_001084979.1|1641745_1642663_-|sugar-ABC-transporter-permease
MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLIAFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAIMLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLTNPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPALKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTAVGLFNAVINVVLLVAVNQIVKRMNNGEGI
>NZ_CP045931.1|WP_000797961.1|1640844_1641735_-|carbohydrate-ABC-transporter-permease
MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDPKVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPLSKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILARAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMIYIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIVMYPFFQKYFDKGIMAGSLKG
>NZ_CP045931.1|WP_000669745.1|1639199_1640816_-|extracellular-solute-binding-protein
MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQEKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDLPDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHIYSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNGNGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVKFIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAGPSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQQNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLDLIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWDDYKKELEKYGLSDYLAIKQKYYDQYQANKN
>NZ_CP045931.1|WP_000502548.1|1637870_1639190_-|glycoside-hydrolase-family-32-protein
MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNGFVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSGSAIVKDDRLWLMYTGHIEEKNGVRQVQNMAFSDDGIHFEKIEQNPVATGADLPDELIAADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMWECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVEWGEKCFIPESVQEIDHGQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQFPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTSRRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID
>NZ_CP045931.1|WP_001113208.1|1636053_1637325_+|replication-associated-recombination-protein-A
MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMILYGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHRLDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQIALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITLDIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYAARLIEAGDLPSLARRLTVIAYEDIGLANPEAQIHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYVAMDKALADLKASGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKIRNHHYFQAEDTGKYERALAQRKEAIDHLRKI
>NZ_CP045931.1|WP_001809903.1|1635201_1635381_-|hypothetical-protein
MNLIFEEYQFVKIGDKKYRVRSGPMIHSTPPQSVLDRDTFTIDYTDDELLDKEAVFTTH
>NZ_CP045931.1|WP_075270892.1|1634885_1635092_-|type-II-toxin-antitoxin-system-HicA-family-toxin
MVLSGGKSAIPMTQKEMVKLLTAHGWIKTRGGKGSHIKIEKQGERPITILHGELNKYTERGIGKQAGL
>NZ_CP045931.1|WP_000961810.1|1634396_1634849_-|type-II-toxin-antitoxin-system-HicB-family-antitoxin
MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAMGSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSVDVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA
>NZ_CP045931.1|WP_000257084.1|1633635_1634106_-|DUF3013-family-protein
MATYGFLDILEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNAAGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNAEDYLTVIPYLPKKGFSREFLAYFALFLKDTAEVGLDTLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY
>NZ_CP045931.1|WP_075270891.1|1632549_1633632_-|site-2-protease-family-protein
MVGGVMKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYAFALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGAQYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLNNILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARGSFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFEQAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLRDEKRYYENLLAELEKELAEGV
>NZ_CP045931.1|WP_000230202.1|1642813_1643815_-|LacI-family-transcriptional-regulator
MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQAIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCSINGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSDNDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDETVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKMAGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS
>NZ_CP045931.1|WP_001205280.1|1644176_1645658_-|aspartate-aminotransferase
MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKDDLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQAESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSEKYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFMEVDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESLFMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEFILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHLVINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSPYDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE
>NZ_CP045931.1|WP_001820409.1|1646100_1646265_+|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein
MGIIANVFAGLVGAYAGQSLLGSWGPSIAEMALLPSIVGAAIVITVVSFFTGRK
>NZ_CP045931.1|WP_000030213.1|1646348_1646915_+|alkaline-shock-response-membrane-anchor-protein-AmaP
MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNSVVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFVRSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFGIERQVKLEVAVKNYQPKPQNKKTVSRVK
>NZ_CP045931.1|WP_000455066.1|1646926_1647097_+|DUF2273-domain-containing-protein
MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVAAGLYIEKNYIDK
>NZ_CP045931.1|WP_000064115.1|1647135_1647744_+|Asp23/Gls24-family-envelope-stress-response-protein
MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLENVSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSEIREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQFEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN
>NZ_CP045931.1|WP_000109957.1|1647774_1647978_+|CsbD-family-protein
MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVAEDAKDAVEGAVEGVKNMLSGDDK
>NZ_CP045931.1|WP_001812322.1|1648669_1648957_+|IS30-family-transposase
MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSKWKDISNHHDSESFFANLGCPRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF
>NZ_CP045931.1|WP_000229335.1|1649234_1650005_-|sulfite-exporter-TauE/SafE-family-protein
MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIAFYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGYLIFQVLLSQLSVRLVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNVSLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGGVLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL
>NZ_CP045931.1|WP_000344536.1|1651163_1651481_-|PTS-lactose/cellobiose-transporter-subunit-IIA
MDESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLADANAALLQAHKAQTEMLTREAQGEKTSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERFEKN

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

22636 : 31474

Streptococcus_phage(75.0%)

integrase

attL 24696:24711|attR 30949:30964

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000205044.1\|22636_23923_+	adenylosuccinate synthase	L7Y4J5	Megavirus	2.7e-72	37.1
WP_000291870.1\|24123_24591_+	nucleoside deaminase	NA	NA	NA	NA
24696:24711	attL	NA	NA	NA	NA
WP_001106362.1\|24799_25498_-\|integrase	site-specific integrase	A0A1S5SDQ9	Streptococcus_phage	6.0e-127	100.0
WP_001814135.1\|25587_25941_-	hypothetical protein	U4KJ82	Streptococcus_phage	4.5e-54	97.3
WP_000401841.1\|25995_27066_-	endonuclease	A0A1S5SAB0	Streptococcus_phage	2.9e-181	97.8
WP_000170931.1\|27082_27463_-	ImmA/IrrE family metallo-endopeptidase	A0A1S5SBG5	Streptococcus_phage	1.7e-67	98.4
WP_000285962.1\|27475_27739_-	type II toxin-antitoxin system RelE/ParE family toxin	A0A1S5S8E8	Streptococcus_phage	1.2e-43	100.0
WP_000156419.1\|27738_27972_-	hypothetical protein	A0A1S5S8D5	Streptococcus_phage	8.9e-35	96.1
WP_000464160.1\|27971_28340_-	helix-turn-helix transcriptional regulator	A0A1S5SBE7	Streptococcus_phage	1.4e-63	100.0
WP_001112859.1\|28911_29103_+	DNA-binding protein	A0A141DZR9	Streptococcus_phage	3.0e-28	100.0
WP_001247549.1\|29125_29329_+	hypothetical protein	A0A141E1R6	Streptococcus_phage	1.3e-29	95.5
WP_000024181.1\|29483_29651_-	YjzC family protein	NA	NA	NA	NA
WP_001209433.1\|30255_30435_-	hypothetical protein	Q3BLW4	Phage_SK137	3.5e-23	96.6
WP_000701992.1\|31030_31474_+	dUTP diphosphatase	Q2WG49	Clostridium_botulinum_D_phage	2.1e-29	47.3
30949:30964	attR	NA	NA	NA	NA

DBSCAN-SWA_2

52127 : 63575

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000668290.1\|52127_54281_+	peptide cleavage/export ABC transporter	W8CYL7	Bacillus_phage	1.0e-44	28.0
WP_154079314.1\|55237_55780_+	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_075270809.1\|55907_56657_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A1D8KNF0	Synechococcus_phage	2.4e-41	39.2
WP_000361208.1\|56713_60439_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	9.6e-38	25.7
WP_000220632.1\|60531_61974_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	5.7e-55	35.1
WP_000182575.1\|62010_63033_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D7SE90	Cyanophage	1.2e-64	43.9
WP_000717506.1\|63029_63575_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	7.4e-24	35.0

DBSCAN-SWA_3

124725 : 178376

Staphylococcus_phage(37.5%)

bacteriocin,protease,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000424474.1\|124725_125100_+\|bacteriocin	SPH_0224 family bacteriocin-like peptide	NA	NA	NA	NA
WP_000511670.1\|125106_125289_+	hypothetical protein	NA	NA	NA	NA
WP_000619774.1\|125307_126210_+	hypothetical protein	NA	NA	NA	NA
WP_075271446.1\|126232_126619_+	argininosuccinate lyase	NA	NA	NA	NA
WP_075285017.1\|126585_127344_+	hypothetical protein	NA	NA	NA	NA
WP_000680086.1\|127816_128014_+	hypothetical protein	NA	NA	NA	NA
WP_001035345.1\|129258_131352_+	pneumococcal surface protein A	NA	NA	NA	NA
WP_001282984.1\|131752_132874_+\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_075271302.1\|132987_133470_+	NUDIX hydrolase	NA	NA	NA	NA
WP_000220946.1\|133479_135393_+\|tRNA	tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG	NA	NA	NA	NA
WP_000331980.1\|135771_137451_-	ribonuclease J	NA	NA	NA	NA
WP_000639577.1\|137452_137686_-	DNA-dependent RNA polymerase auxiliary subunit epsilon family protein	NA	NA	NA	NA
WP_001844323.1\|138312_138510_-	hypothetical protein	NA	NA	NA	NA
WP_000977347.1\|138503_138656_-\|bacteriocin	fratricide two-peptide bacteriocin subunit CibB	NA	NA	NA	NA
WP_000180803.1\|138657_138843_-\|bacteriocin	fratricide two-peptide bacteriocin subunit CibA	NA	NA	NA	NA
WP_000865692.1\|139020_139704_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA
WP_000569820.1\|139700_140138_+	ribosomal-protein-alanine N-acetyltransferase	NA	NA	NA	NA
WP_000655047.1\|140127_141138_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	NA	NA	NA	NA
WP_000375722.1\|144952_145906_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_000288029.1\|145915_147532_+	ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	3.0e-28	36.0
WP_047475175.1\|147880_148309_+	hypothetical protein	NA	NA	NA	NA
WP_073506749.1\|148314_149070_+	PIG-L family deacetylase	NA	NA	NA	NA
WP_047475171.1\|150648_151512_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_000933464.1\|151794_151995_+	peptide pheromone VP1	NA	NA	NA	NA
WP_000720790.1\|152061_152727_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000862431.1\|152798_154025_+	MFS transporter	NA	NA	NA	NA
WP_001141646.1\|154522_155179_+	AzlC family ABC transporter permease	NA	NA	NA	NA
WP_000253940.1\|155168_155378_+	hypothetical protein	NA	NA	NA	NA
WP_000724936.1\|155595_156426_+	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000694501.1\|156579_157434_+	MetQ/NlpA family ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000231826.1\|157533_158907_+	M20/M25/M40 family metallo-hydrolase	NA	NA	NA	NA
WP_000085657.1\|158899_159961_+	methionine ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.0e-28	35.3
WP_000444655.1\|159962_160655_+	ABC transporter permease	NA	NA	NA	NA
WP_000748391.1\|160683_161253_-	MptD family putative ECF transporter S component	NA	NA	NA	NA
WP_000532353.1\|161387_162002_+	YesL family protein	NA	NA	NA	NA
WP_000800582.1\|161979_163650_+	sensor histidine kinase	NA	NA	NA	NA
WP_000278862.1\|163661_164948_+	response regulator transcription factor	NA	NA	NA	NA
WP_010976398.1\|164951_165533_+	hypothetical protein	NA	NA	NA	NA
WP_000849621.1\|165610_166081_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	NA	NA	NA	NA
WP_000075789.1\|166373_167636_-	divalent metal cation transporter	NA	NA	NA	NA
WP_001155339.1\|167778_168732_-\|transposase	IS30-like element ISSpn8 family transposase	H7BWC8	unidentified_phage	8.1e-34	34.9
WP_000745059.1\|169191_169650_-	DUF3021 domain-containing protein	NA	NA	NA	NA
WP_000861955.1\|169646_170087_-	response regulator transcription factor	NA	NA	NA	NA
WP_073077623.1\|170326_170407_+	hypothetical protein	NA	NA	NA	NA
WP_000018169.1\|170442_172392_+	DNA mismatch repair protein HexB	A0A1B2LRQ5	Wolbachia_phage	1.0e-70	32.1
WP_001099502.1\|172716_173184_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	3.7e-40	52.6
WP_001813190.1\|173184_174390_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	7.7e-106	49.5
WP_000493839.1\|174409_175045_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	9.9e-44	46.9
WP_001284096.1\|175029_176130_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A1V0SE20	Indivirus	3.8e-51	38.2
WP_000271493.1\|176535_177129_+	Holliday junction branch migration protein RuvA	NA	NA	NA	NA
WP_000166597.1\|177138_177702_+	DNA-3-methyladenine glycosylase I	NA	NA	NA	NA
WP_000987428.1\|177698_178376_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_4

276552 : 347508

Streptococcus_phage(28.57%)

protease,integrase,transposase,holin

attL 272866:272881|attR 291709:291724

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
272866:272881	attL	NA	NA	NA	NA
WP_001211068.1\|276552_276975_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_000050748.1\|277121_277298_+	hypothetical protein	NA	NA	NA	NA
WP_041172756.1\|277699_279913_+	alpha-xylosidase	NA	NA	NA	NA
WP_041172755.1\|280134_280611_-	glutathione peroxidase	NA	NA	NA	NA
WP_075271307.1\|280800_284037_+	LPXTG-anchored hyaluronate lyase	NA	NA	NA	NA
WP_000167294.1\|285203_285833_-	bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase	NA	NA	NA	NA
WP_000161486.1\|285842_286844_-	sugar kinase	NA	NA	NA	NA
WP_041172762.1\|286874_287516_-	RpiB/LacA/LacB family sugar-phosphate isomerase	NA	NA	NA	NA
WP_000185874.1\|287534_288350_-	gluconate 5-dehydrogenase	NA	NA	NA	NA
WP_000706826.1\|288621_289056_+	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_000592948.1\|289067_290258_+	unsaturated chondroitin disaccharide hydrolase	NA	NA	NA	NA
WP_047474126.1\|290268_290760_+	PTS system mannose/fructose/N-acetylgalactosamine-transporter subunit IIB	NA	NA	NA	NA
WP_000026610.1\|290774_291554_+	PTS mannose/fructose/sorbose/N-acetylgalactosamine transporter subunit IIC	NA	NA	NA	NA
WP_000148019.1\|291540_292359_+	PTS mannose/fructose/sorbose transporter family subunit IID	NA	NA	NA	NA
291709:291724	attR	NA	NA	NA	NA
WP_000381738.1\|292358_292652_+	preprotein translocase subunit YajC	NA	NA	NA	NA
WP_047474124.1\|292673_294575_+	alginate lyase family protein	NA	NA	NA	NA
WP_001844476.1\|294568_295636_+	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_154079316.1\|295745_296081_-	hypothetical protein	NA	NA	NA	NA
WP_000711818.1\|296091_296334_-	hypothetical protein	NA	NA	NA	NA
WP_047474120.1\|296344_296887_-	DUF3278 domain-containing protein	NA	NA	NA	NA
WP_001082474.1\|296902_297097_-	helix-turn-helix transcriptional regulator	I3VYZ1	Thermoanaerobacterium_phage	7.2e-06	42.6
WP_000159408.1\|297262_298213_+	16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH	NA	NA	NA	NA
WP_000818547.1\|298224_298542_+	cell division protein FtsL	NA	NA	NA	NA
WP_047474114.1\|298545_300798_+	PASTA domain-containing protein	NA	NA	NA	NA
WP_000470828.1\|300799_301780_+	phospho-N-acetylmuramoyl-pentapeptide- transferase	NA	NA	NA	NA
WP_047474113.1\|302388_304494_+\|protease	ATP-dependent Clp protease ATP-binding subunit	H6X3M6	Enterobacteria_phage	2.9e-116	37.4
WP_000032550.1\|304789_305272_-	S-ribosylhomocysteine lyase	NA	NA	NA	NA
WP_000743575.1\|305366_306851_-	DUF1846 domain-containing protein	NA	NA	NA	NA
WP_047474112.1\|307003_308611_+	alpha-glucosidase	NA	NA	NA	NA
WP_033607495.1\|308775_308943_+	S-ribosylhomocysteinase	NA	NA	NA	NA
WP_047474105.1\|309683_311129_+	LCP family protein	A0A1X9I5X1	Streptococcus_phage	1.9e-135	61.1
WP_000565355.1\|311130_311862_+	tyrosine protein phosphatase	NA	NA	NA	NA
WP_000664155.1\|311870_312563_+	capsular polysaccharide biosynthesis protein CpsC	A0A1X9I5E1	Streptococcus_phage	3.2e-64	58.5
WP_154079317.1\|312572_313262_+	polysaccharide biosynthesis tyrosine autokinase	A0A1X9I5D6	Streptococcus_phage	4.2e-72	63.7
WP_024477745.1\|313276_314638_+	sugar transferase	NA	NA	NA	NA
WP_001005725.1\|314643_315387_+	WecB/TagA/CpsF family glycosyltransferase	NA	NA	NA	NA
WP_001076780.1\|315383_316208_+\|holin	LPS cholinephosphotransferase	A0A1V0SD50	Indivirus	4.0e-05	38.2
WP_000458862.1\|316209_317088_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_000221685.1\|317088_318423_+	oligosaccharide repeat unit polymerase	NA	NA	NA	NA
WP_001085099.1\|318450_319875_+	hypothetical protein	NA	NA	NA	NA
WP_000723325.1\|319939_321028_+	UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)	A0A1V0SAG5	Catovirus	1.6e-25	30.2
WP_000676130.1\|321190_322060_+	glucose-1-phosphate thymidylyltransferase RfbA	K7QKA7	Escherichia_phage	2.0e-100	63.2
WP_001282454.1\|322060_322654_+	dTDP-4-dehydrorhamnose 3,5-epimerase	H9NC63	Sphingomonas_phage	3.3e-09	32.3
WP_000141492.1\|322665_323712_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	3.1e-71	43.7
WP_000600921.1\|323773_324628_-	dTDP-4-dehydrorhamnose reductase	A0A140G5S3	Enterobacteria_phage	1.7e-27	36.6
WP_000842568.1\|324873_326856_+	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_047474091.1\|327155_332459_+	YSIRK-type signal peptide-containing protein	NA	NA	NA	NA
WP_001039998.1\|332625_334785_-	PBP1A family penicillin-binding protein	NA	NA	NA	NA
WP_000248787.1\|334781_335378_-	Holliday junction resolvase RecU	A0A1L2JY30	Aeribacillus_phage	8.7e-18	33.9
WP_000179553.1\|335443_335971_+	DUF1273 domain-containing protein	NA	NA	NA	NA
WP_001808467.1\|336028_336370_+	cell division regulator GpsB	NA	NA	NA	NA
WP_050230812.1\|336855_338013_+	class I SAM-dependent RNA methyltransferase	NA	NA	NA	NA
WP_000039301.1\|338025_339396_+	mid-cell-anchored protein MapZ	NA	NA	NA	NA
WP_000158799.1\|339471_340896_+	NADP-dependent phosphogluconate dehydrogenase	M4QQM4	Ostreococcus_lucimarinus_virus	7.9e-41	29.4
WP_047474084.1\|340907_341597_+	response regulator transcription factor	NA	NA	NA	NA
WP_000771107.1\|341694_342591_+\|holin	choline-binding protein CbpC	NA	NA	NA	NA
WP_000765684.1\|342708_343941_-	MFS transporter	NA	NA	NA	NA
WP_001820155.1\|344469_344808_-	lantibiotic-modifying protein	NA	NA	NA	NA
WP_001808790.1\|345359_346706_+\|transposase	IS1380-like element ISSpn5 family transposase	A0A1X9I6F6	Streptococcus_phage	5.8e-78	40.0
WP_000619579.1\|347178_347508_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_5

433125 : 480825

Only_Syngen_Nebraska_virus(12.5%)

bacteriocin,protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000181373.1\|433125_433629_+\|tRNA	tRNA (cytidine(34)-2'-O)-methyltransferase	NA	NA	NA	NA
WP_000185835.1\|434081_434645_+	ECF transporter S component	NA	NA	NA	NA
WP_000653434.1\|434634_435285_+	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_000867290.1\|435312_435702_+	chromosome partitioning protein ParB	NA	NA	NA	NA
WP_000333648.1\|435706_436156_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_001808720.1\|436268_436871_+	DNA-directed RNA polymerase subunit delta	NA	NA	NA	NA
WP_000105242.1\|437260_438868_+	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	8.9e-142	47.0
WP_000026645.1\|439426_441058_-	Na/Pi cotransporter family protein	NA	NA	NA	NA
WP_000795181.1\|441366_446346_+	YSIRK-type signal peptide-containing protein	NA	NA	NA	NA
WP_001096743.1\|446435_447632_+	phosphoglycerate kinase	NA	NA	NA	NA
WP_000119900.1\|447767_448295_+	aromatic acid exporter family protein	NA	NA	NA	NA
WP_000659547.1\|448371_448728_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_001122904.1\|448764_450111_+	type I glutamate--ammonia ligase	NA	NA	NA	NA
WP_001808898.1\|450206_450326_-	hypothetical protein	NA	NA	NA	NA
WP_000410534.1\|450290_450440_+	hypothetical protein	NA	NA	NA	NA
WP_001220761.1\|450891_452172_+	type I restriction-modification protein subunit S	A0A1V0SKS6	Klosneuvirus	6.9e-12	29.2
WP_000651177.1\|452228_453026_+	tyrosine-type DNA invertase PsrA	A0A0H4TI16	Erysipelothrix_phage	1.3e-21	28.7
WP_154079318.1\|453938_454976_-	restriction endonuclease subunit S	NA	NA	NA	NA
WP_000029036.1\|454975_456439_-	SAM-dependent DNA methyltransferase	NA	NA	NA	NA
WP_000229106.1\|456451_458785_-	DEAD/DEAH box helicase	A0A097BY72	Enterococcus_phage	9.9e-25	28.9
WP_013193390.1\|459157_459358_+	hypothetical protein	NA	NA	NA	NA
WP_001820185.1\|459392_459899_+	DUF2812 domain-containing protein	NA	NA	NA	NA
WP_000255785.1\|460066_461101_+	heat-inducible transcriptional repressor HrcA	NA	NA	NA	NA
WP_000046027.1\|461127_461652_+	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_000034662.1\|462131_463955_+	molecular chaperone DnaK	A0A0N9QXN8	Chrysochromulina_ericina_virus	1.3e-133	47.2
WP_000114422.1\|463956_464313_+	hypothetical protein	NA	NA	NA	NA
WP_001066295.1\|464714_465851_+	molecular chaperone DnaJ	E3T4P7	Cafeteria_roenbergensis_virus	2.4e-24	31.3
WP_001808905.1\|466184_466379_-	hypothetical protein	NA	NA	NA	NA
WP_000777753.1\|466540_466828_-	hypothetical protein	NA	NA	NA	NA
WP_001278301.1\|466837_467248_-	HIT family protein	B5LJ12	Mycobacterium_phage	3.4e-05	31.6
WP_000889921.1\|467315_468047_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	5.3e-25	28.6
WP_000653771.1\|468043_469093_+	multidrug ABC transporter permease	NA	NA	NA	NA
WP_000132572.1\|469260_469590_-	hypothetical protein	NA	NA	NA	NA
WP_000876675.1\|469865_470204_+	response regulator transcription factor	NA	NA	NA	NA
WP_000643611.1\|470277_470946_+	response regulator transcription factor	NA	NA	NA	NA
WP_050073044.1\|470959_472300_+	sensor histidine kinase	NA	NA	NA	NA
WP_000358815.1\|472370_472499_-	quorum-sensing system pheromone BlpC	NA	NA	NA	NA
WP_001069060.1\|472555_473917_-\|bacteriocin	bacteriocin secretion accessory protein	NA	NA	NA	NA
WP_001093259.1\|476366_476564_+\|bacteriocin	bacteriocin-like peptide BlpI	NA	NA	NA	NA
WP_001093248.1\|477030_477300_+\|bacteriocin	bacteriocin-like peptide BlpJ	NA	NA	NA	NA
WP_047475057.1\|477368_477617_+\|bacteriocin	bacteriocin-like peptide BlpK	NA	NA	NA	NA
WP_001809846.1\|477860_478010_+\|bacteriocin	bacteriocin-like peptide BlpO	NA	NA	NA	NA
WP_000346296.1\|478113_478233_+	hypothetical protein	NA	NA	NA	NA
WP_000727120.1\|478529_478691_+	hypothetical protein	NA	NA	NA	NA
WP_001821950.1\|478700_479072_+	hypothetical protein	NA	NA	NA	NA
WP_001844594.1\|479685_480084_+	hypothetical protein	NA	NA	NA	NA
WP_000760532.1\|480135_480825_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_6

843221 : 855040

Streptococcus_phage(72.73%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001025704.1\|843221_844130_+	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	3.1e-06	27.7
WP_000745389.1\|844126_844588_+	signal peptidase II	NA	NA	NA	NA
WP_000403199.1\|844577_845465_+	RluA family pseudouridine synthase	A0A2H4UV25	Bodo_saltans_virus	1.7e-09	28.0
WP_000728276.1\|845467_847351_+	MBL fold metallo-hydrolase	Q332B9	Clostridium_botulinum_C_phage	1.2e-09	22.9
WP_075218898.1\|847430_848561_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.1e-114	58.4
WP_000254684.1\|848570_849833_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	4.2e-139	64.3
WP_000689706.1\|849836_850634_+	pyrroline-5-carboxylate reductase	A0A1X9I6T5	Streptococcus_phage	8.0e-59	50.2
WP_000033397.1\|850853_851492_+	dTMP kinase	M1PSC7	Streptococcus_phage	1.3e-75	68.1
WP_000806714.1\|851488_852379_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	4.9e-73	51.7
WP_000358228.1\|852418_852736_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	2.9e-28	60.0
WP_001166870.1\|852738_853608_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	3.8e-115	75.4
WP_001261449.1\|853834_854353_+	ClbS/DfsB family four-helix bundle protein	NA	NA	NA	NA
WP_000345256.1\|854461_854599_+	hypothetical protein	NA	NA	NA	NA
WP_000008691.1\|854605_855040_+	replication initiator protein A	A0A2P0VK56	Streptococcus_phage	4.6e-08	40.0

DBSCAN-SWA_7

1163865 : 1217422

Bacillus_phage(27.27%)

holin,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000811991.1\|1163865_1164669_+\|holin	phosphorylcholine transferase LicD	A0A1V0SD50	Indivirus	4.0e-10	27.1
WP_001199649.1\|1164670_1165480_+\|holin	phosphorylcholine transferase LicD	A0A1V0SD50	Indivirus	9.1e-10	30.3
WP_001126425.1\|1165754_1168931_-	carbamoyl-phosphate synthase large subunit	NA	NA	NA	NA
WP_000166701.1\|1169242_1170322_-	carbamoyl-phosphate synthase small subunit	R4TGJ8	Halovirus	6.3e-59	35.9
WP_001293838.1\|1170371_1171295_-	aspartate carbamoyltransferase	M1HGA5	Paramecium_bursaria_Chlorella_virus	5.1e-25	31.7
WP_000850024.1\|1171313_1171835_-	bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase PyrR	NA	NA	NA	NA
WP_000244451.1\|1172045_1172675_-	endonuclease III	NA	NA	NA	NA
WP_000773231.1\|1172674_1173217_-	DUF177 domain-containing protein	NA	NA	NA	NA
WP_001861318.1\|1173940_1175500_+	ABC-F family ATP-binding cassette domain-containing protein	A0A1B0RXA0	Streptococcus_phage	9.3e-11	27.5
WP_000895733.1\|1175648_1176548_-\|protease	zinc metalloprotease HtpX	NA	NA	NA	NA
WP_000219823.1\|1176549_1177110_-	LemA family protein	NA	NA	NA	NA
WP_000801931.1\|1177203_1177917_+	16S rRNA (guanine(527)-N(7))-methyltransferase RsmG	NA	NA	NA	NA
WP_000534454.1\|1178183_1179503_+	uracil transporter	Q9KX94	Enterobacteria_phage	2.7e-59	35.0
WP_000863628.1\|1179697_1181269_-	signal recognition particle protein	NA	NA	NA	NA
WP_000402066.1\|1181280_1181613_-	putative DNA-binding protein	NA	NA	NA	NA
WP_001813294.1\|1181703_1182081_-	DUF1934 domain-containing protein	NA	NA	NA	NA
WP_001003484.1\|1182152_1183457_+	HD domain-containing protein	E3T4P8	Cafeteria_roenbergensis_virus	5.0e-26	29.8
WP_000023528.1\|1183469_1184276_+	sugar-phosphatase	NA	NA	NA	NA
WP_001068669.1\|1184443_1184791_-	50S ribosomal protein L19	NA	NA	NA	NA
WP_000237409.1\|1184909_1185239_-	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	8.2e-10	37.8
WP_000712093.1\|1185232_1185607_-	fluoride efflux transporter CrcB	NA	NA	NA	NA
WP_000362438.1\|1185603_1185870_-	chorismate mutase	NA	NA	NA	NA
WP_001162129.1\|1185985_1186429_-	flavodoxin	NA	NA	NA	NA
WP_000401773.1\|1186532_1187468_+	bifunctional oligoribonuclease/PAP phosphatase NrnA	NA	NA	NA	NA
WP_000710764.1\|1187563_1187806_+	type B 50S ribosomal protein L31	NA	NA	NA	NA
WP_000252103.1\|1187862_1188441_-	hypothetical protein	NA	NA	NA	NA
WP_000199566.1\|1190405_1191752_+	NADP-specific glutamate dehydrogenase	NA	NA	NA	NA
WP_000711943.1\|1192257_1192428_-	hypothetical protein	NA	NA	NA	NA
WP_144423368.1\|1193035_1193840_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_000424224.1\|1195029_1195479_-	DUF386 family protein	NA	NA	NA	NA
WP_001000318.1\|1195983_1196439_-	HIT domain-containing protein	NA	NA	NA	NA
WP_000272434.1\|1196460_1197921_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_000239901.1\|1197980_1199558_-	extracellular solute-binding protein	NA	NA	NA	NA
WP_001180441.1\|1199626_1201066_-	hypothetical protein	NA	NA	NA	NA
WP_000577773.1\|1201079_1202009_-	carbohydrate ABC transporter permease	NA	NA	NA	NA
WP_001071050.1\|1202019_1202952_-	sugar ABC transporter permease	NA	NA	NA	NA
WP_000448317.1\|1202952_1203639_-	N-acetylmannosamine-6-phosphate 2-epimerase	NA	NA	NA	NA
WP_078101602.1\|1204356_1205115_-	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
WP_001165928.1\|1205292_1205901_+	DUF624 domain-containing protein	NA	NA	NA	NA
WP_087671856.1\|1206135_1207487_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	6.5e-61	50.6
WP_000807141.1\|1207782_1207920_-	hypothetical protein	NA	NA	NA	NA
WP_000945302.1\|1208053_1209373_-	membrane protein	NA	NA	NA	NA
WP_001843896.1\|1209375_1210134_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	7.2e-09	30.8
WP_001108416.1\|1210130_1211738_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	6.6e-12	22.0
WP_001076600.1\|1211734_1213675_-	S9 family peptidase	NA	NA	NA	NA
WP_000257531.1\|1213707_1214172_-	hypothetical protein	NA	NA	NA	NA
WP_001058020.1\|1214196_1216206_-	phosphotransferase	NA	NA	NA	NA
WP_000807141.1\|1216495_1216633_-	hypothetical protein	NA	NA	NA	NA
WP_000821280.1\|1216834_1217422_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_8

1309960 : 1316968

Streptococcus_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000930000.1\|1309960_1310677_-	CapA family protein	A0A0N9SJ77	Staphylococcus_phage	3.0e-25	30.7
WP_001272961.1\|1311189_1311801_+	peptide deformylase	E3SLL2	Synechococcus_phage	4.9e-16	42.4
WP_000855754.1\|1311845_1312574_+	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	NA	NA	NA	NA
WP_000272308.1\|1312612_1313524_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	3.8e-89	51.1
WP_001206969.1\|1313589_1313826_-	DUF4059 family protein	NA	NA	NA	NA
WP_000590986.1\|1313891_1314635_-	amino acid ABC transporter ATP-binding protein	W5SAS9	Pithovirus	1.6e-13	27.4
WP_001103449.1\|1314634_1315435_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_000889093.1\|1315592_1315949_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	1.2e-33	57.3
WP_001170346.1\|1315961_1316474_-	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	1.3e-46	55.6
WP_000405832.1\|1316473_1316968_-	GNAT family N-acetyltransferase	M1PSC3	Streptococcus_phage	1.9e-42	52.1

DBSCAN-SWA_9

1418856 : 1425607

Streptococcus_phage(50.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000081011.1\|1418856_1419822_+	NAD(P)/FAD-dependent oxidoreductase	Q9JRK7	Streptococcus_phage	2.8e-66	100.0
WP_000011293.1\|1419855_1420767_-	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	1.2e-154	99.7
WP_001231086.1\|1420763_1421741_-	YvcK family protein	A1IMD5	Streptococcus_phage	1.2e-184	100.0
WP_000163031.1\|1421737_1422628_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	1.1e-05	29.8
WP_001140412.1\|1422679_1423060_-	RidA family protein	NA	NA	NA	NA
WP_000422599.1\|1423070_1423658_-	YihA family ribosome biogenesis GTP-binding protein	NA	NA	NA	NA
WP_000106346.1\|1423666_1424899_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	4.2e-131	59.0
WP_000442275.1\|1424930_1425101_-	hypothetical protein	NA	NA	NA	NA
WP_000162503.1\|1425100_1425607_-	dihydrofolate reductase	A0A1B2IAU3	Erwinia_phage	1.0e-19	32.8

DBSCAN-SWA_10

1709640 : 1716972

uncultured_Mediterranean_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000167830.1\|1709640_1710342_+	UDP-glucose 4-epimerase GalE	A0A2K9L1R4	Tupanvirus	1.2e-34	36.5
WP_001844979.1\|1710749_1711724_+	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	1.8e-57	40.8
WP_001193673.1\|1711713_1712670_+	iron chelate uptake ABC transporter family permease subunit	NA	NA	NA	NA
WP_000764300.1\|1712666_1713419_+	ATP-binding cassette domain-containing protein	W6JKT0	Anomala_cuprea_entomopoxvirus	9.6e-14	28.1
WP_000858249.1\|1713514_1714480_+	siderophore ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000821640.1\|1714704_1714947_-	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	1.3e-17	59.4
WP_001222228.1\|1714946_1715669_-	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_000105310.1\|1715655_1716225_-	segregation/condensation protein B	A0A1B1IVT7	uncultured_Mediterranean_phage	5.0e-15	34.9
WP_000351907.1\|1716243_1716972_-	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	5.3e-09	22.3

DBSCAN-SWA_11

2068449 : 2077203

Streptococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000510412.1\|2068449_2069289_-	energy-coupling factor transporter ATPase	A0A2H4PQG7	Staphylococcus_phage	1.1e-13	27.6
WP_000835715.1\|2069273_2070101_-	energy-coupling factor transporter ATPase	W8CYL7	Bacillus_phage	3.5e-17	33.3
WP_000712132.1\|2070097_2070643_-	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_075271383.1\|2070653_2071484_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_000170215.1\|2071516_2072800_-	insulinase family protein	A0A1E1EST3	Acanthamoeba_castellanii_mimivirus	8.4e-18	30.0
WP_000424271.1\|2072796_2074047_-	insulinase family protein	A0A1X9I714	Streptococcus_phage	2.7e-93	42.3
WP_000455903.1\|2074205_2074574_+	S4 domain-containing protein YaaA	A0A1X9I5V8	Streptococcus_phage	7.0e-18	57.3
WP_000266660.1\|2074576_2075674_+	DNA replication/repair protein RecF	NA	NA	NA	NA
WP_000073428.1\|2075724_2077203_-	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	2.2e-94	40.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP045931

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection