CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP035699	Vibrio alginolyticus strain 2013V-1302 chromosome 2, complete sequence	0 crisprs	DEDDh,cas3,csa3,WYL	0	0	0	0
NZ_CP035700	Vibrio alginolyticus strain 2013V-1302 chromosome 1, complete sequence	0 crisprs	DEDDh,DinG,cas3,csx1,csa3	0	0	5	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

407456 : 417646

Vibrio_phage(75.0%)

coat

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_154204582.1\|407456_408809_-	type II secretory pathway protein	R9TEZ5	Vibrio_phage	1.3e-122	59.5
WP_154205197.1\|408826_409900_-	hypothetical protein	O80263	Vibrio_phage	3.5e-126	62.8
WP_024701224.1\|409899_410259_-	hypothetical protein	R9TIT8	Vibrio_phage	4.6e-22	45.6
WP_021448020.1\|411928_412192_-\|coat	phage major coat, Gp8 family protein	R9TI50	Vibrio_phage	6.3e-05	40.3
WP_154205198.1\|412462_412768_-	chemotaxis protein	Q2PZB5	Vibrio_virus	1.1e-19	51.0
WP_154204583.1\|412851_414882_-	replication endonuclease	A0A0F6YPA7	Vibrio_phage	4.7e-196	53.0
WP_154204584.1\|414881_415184_-	hypothetical protein	NA	NA	NA	NA
WP_053048103.1\|415382_415751_+	hypothetical protein	R9TE55	Vibrio_phage	1.8e-42	71.1
WP_154204585.1\|415924_417646_-	response regulator	A0A1V0SGX0	Hokovirus	5.0e-42	31.9

DBSCAN-SWA_2

1352395 : 1359179

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005381572.1\|1352395_1352866_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.7e-32	48.7
WP_005381573.1\|1353035_1354145_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	1.2e-65	39.8
WP_154204799.1\|1354318_1354972_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	8.0e-33	37.0
WP_017635684.1\|1354980_1356108_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A1V0SE20	Indivirus	5.4e-45	34.8
WP_005381578.1\|1356115_1356565_-	transcriptional regulator NrdR	NA	NA	NA	NA
WP_154204800.1\|1356771_1358022_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	1.1e-99	48.6
WP_017820604.1\|1358039_1359179_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	5.8e-63	42.0

DBSCAN-SWA_3

1431948 : 1438367

Clostridium_phage(16.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_017633711.1\|1431948_1432383_-\|transposase	IS200/IS605 family transposase	A0A0A8WIU6	Clostridium_phage	7.2e-14	31.2
WP_154204821.1\|1432571_1432997_-	nucleoside-diphosphate kinase	A0A2P1ELL9	Moumouvirus	6.0e-21	42.1
WP_154204822.1\|1433092_1434391_-	aminopeptidase PepB	Q6GYZ8	Mycoplasma_phage	8.5e-34	34.6
WP_005381711.1\|1434552_1434747_-	Fe-S cluster assembly protein IscX	NA	NA	NA	NA
WP_005381713.1\|1434791_1435130_-	ISC system 2Fe-2S type ferredoxin	NA	NA	NA	NA
WP_017820567.1\|1435143_1436997_-	Fe-S protein assembly chaperone HscA	A0A0N9QXN8	Chrysochromulina_ericina_virus	3.0e-109	40.8
WP_042521163.1\|1437018_1437534_-	co-chaperone HscB	NA	NA	NA	NA
WP_005381717.1\|1437589_1437913_-	iron-sulfur cluster assembly protein IscA	A0A2H4N7N5	Lake_Baikal_phage	8.9e-25	49.5
WP_005381718.1\|1437983_1438367_-	Fe-S cluster assembly scaffold IscU	A0A218MKD1	uncultured_virus	7.0e-53	79.0

DBSCAN-SWA_4

2613487 : 2632971

uncultured_Mediterranean_phage(15.38%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_021034029.1\|2613487_2615128_+	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	2.1e-154	52.1
WP_005383785.1\|2615206_2616508_+	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	4.1e-137	60.6
WP_005380907.1\|2616910_2617192_+	cell division protein FtsB	NA	NA	NA	NA
WP_154205035.1\|2617193_2617901_+	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	A0A2H4UTB4	Bodo_saltans_virus	7.0e-06	24.3
WP_005380896.1\|2617915_2618392_+	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	NA	NA	NA	NA
WP_154205036.1\|2618437_2619481_+\|tRNA	tRNA pseudouridine(13) synthase TruD	NA	NA	NA	NA
WP_005380894.1\|2619480_2620257_+	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	2.3e-66	49.4
WP_005380892.1\|2620256_2620883_+	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	2.3e-37	54.5
WP_154205037.1\|2620896_2621820_+	murein hydrolase activator NlpD	D7RWE0	Brochothrix_phage	4.1e-06	35.2
WP_005380887.1\|2621900_2622887_+	RNA polymerase sigma factor RpoS	F4YCU2	Synechococcus_phage	6.9e-36	35.2
WP_154205038.1\|2622969_2625531_-	DNA mismatch repair protein MutS	A0A1V0SC35	Catovirus	1.3e-30	23.2
WP_154205039.1\|2625615_2626098_+	nicotinamide-nucleotide amidase	B5TK85	Pseudomonas_phage	2.4e-26	48.1
WP_005380874.1\|2626298_2627342_+	recombinase RecA	A0A2D1GPX2	Mycobacterium_phage	8.1e-112	61.0
WP_137282514.1\|2627341_2627578_+	hypothetical protein	NA	NA	NA	NA
WP_154205040.1\|2627469_2627937_+	recombination regulator RecX	NA	NA	NA	NA
WP_154205041.1\|2628079_2630662_+\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	2.7e-79	38.1
WP_005383803.1\|2630874_2632062_+	aspartate kinase	NA	NA	NA	NA
WP_004415691.1\|2632154_2632352_+	carbon storage regulator CsrA	A0A2I7RT00	Vibrio_phage	5.2e-12	66.7
WP_154204313.1\|2632536_2632971_+\|transposase	IS200/IS605 family transposase	A0A0A8WIU6	Clostridium_phage	3.3e-14	32.0

DBSCAN-SWA_5

3079756 : 3111769

Vibrio_phage(91.43%)

head,capsid,integrase,tail,portal,terminase

attL 3071040:3071054|attR 3082212:3082226

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3071040:3071054	attL	NA	NA	NA	NA
WP_154205126.1\|3079756_3080779_-\|integrase	tyrosine-type recombinase/integrase	R9TMQ4	Vibrio_phage	8.0e-96	52.6
WP_154205127.1\|3081012_3082275_-	LlaJI family restriction endonuclease	NA	NA	NA	NA
3082212:3082226	attR	NA	NA	NA	NA
WP_154205128.1\|3082284_3083715_-	AAA domain-containing protein	M1NSM1	Streptococcus_phage	1.0e-43	38.0
WP_053304191.1\|3083795_3085136_+	DNA (cytosine-5-)-methyltransferase	Q6DMX0	Streptococcus_phage	9.5e-113	54.7
WP_154205129.1\|3085180_3086746_-	hypothetical protein	NA	NA	NA	NA
WP_154205130.1\|3086742_3087366_-	transcriptional regulator	A0A2I7RNF9	Vibrio_phage	1.0e-37	39.6
WP_045607456.1\|3087458_3087671_+	hypothetical protein	U3PFJ1	Vibrio_phage	3.0e-13	52.9
WP_154205131.1\|3087785_3088325_+	transcriptional regulator	A0A2I7RNI1	Vibrio_phage	1.3e-52	57.5
WP_042765728.1\|3088353_3088554_+	hypothetical protein	A0A2I7RNH0	Vibrio_phage	1.5e-11	67.3
WP_154205132.1\|3088553_3088781_+	hypothetical protein	U3PIK2	Vibrio_phage	1.3e-17	53.3
WP_154205133.1\|3088777_3089014_+	hypothetical protein	NA	NA	NA	NA
WP_154205134.1\|3089019_3090900_+	replication endonuclease	A0A218M4H2	Erwinia_phage	3.3e-63	37.7
WP_053304198.1\|3090982_3091246_+	hypothetical protein	Q8HA64	Vibrio_phage	9.8e-14	56.9
WP_154205135.1\|3091240_3091492_-	transcriptional regulator	R9TNQ2	Vibrio_phage	1.1e-30	75.9
WP_154205136.1\|3091557_3092589_-\|portal	phage portal protein	A0A2I7RNI9	Vibrio_phage	4.4e-150	75.4
WP_154205137.1\|3092585_3094373_-\|terminase	terminase	A0A2I7RNI3	Vibrio_phage	2.4e-268	79.0
WP_154205138.1\|3094549_3095422_+\|capsid	capsid protein	A0A2I7RNH1	Vibrio_phage	1.3e-75	57.4
WP_154205139.1\|3095421_3096444_+\|capsid	phage major capsid protein, P2 family	R9TPZ5	Vibrio_phage	9.8e-110	63.2
WP_154205140.1\|3096436_3097153_+\|terminase	terminase	A0A2I7RNJ0	Vibrio_phage	8.1e-87	68.7
WP_154205141.1\|3097261_3097726_+\|head	head protein	U3PFL1	Vibrio_phage	1.1e-52	69.5
WP_053808827.1\|3097722_3098211_+	hypothetical protein	R9TRS7	Vibrio_phage	1.6e-46	55.1
WP_154205142.1\|3098203_3098863_+	phage virion morphogenesis protein	U3PDG7	Vibrio_phage	3.0e-80	71.6
WP_154205143.1\|3098865_3099996_+	DUF2586 family protein	U3PB71	Vibrio_phage	3.8e-123	61.7
WP_017821175.1\|3099999_3100452_+	DUF2597 family protein	U3PCG7	Vibrio_phage	4.4e-54	67.1
WP_017635443.1\|3100472_3100679_+	molecular chaperone DnaK	A0A2I7RNJ6	Vibrio_phage	6.5e-13	52.9
WP_017635442.1\|3100683_3100893_+	hypothetical protein	A0A2I7RNJ2	Vibrio_phage	4.4e-17	58.8
WP_154205144.1\|3100879_3101470_+	glycoside hydrolase family protein	A0A2I7RNI5	Vibrio_phage	2.5e-65	59.7
WP_064368662.1\|3101444_3101786_+	hypothetical protein	R9TNR2	Vibrio_phage	5.8e-35	69.0
WP_119184768.1\|3101742_3101997_+	hypothetical protein	U3PCH1	Vibrio_phage	5.3e-25	73.0
WP_064368661.1\|3101989_3102271_+	hypothetical protein	A0A160DHS7	Vibrio_phage	4.1e-26	66.3
WP_064368660.1\|3102486_3104466_+\|tail	phage tail tape measure protein	R9TRA2	Vibrio_phage	2.9e-211	60.2
WP_017821183.1\|3104455_3104797_+	DUF2590 family protein	R9TMS7	Vibrio_phage	1.0e-34	70.0
WP_154205145.1\|3104793_3105999_+	hypothetical protein	R9TRT3	Vibrio_phage	4.2e-160	69.2
WP_042522470.1\|3105991_3106588_+	phage protein	R9TQ05	Vibrio_phage	5.7e-70	67.0
WP_064368658.1\|3106594_3108373_+	hypothetical protein	A0A160DJT8	Vibrio_phage	1.0e-85	55.3
WP_064368657.1\|3108376_3108778_+	hypothetical protein	NA	NA	NA	NA
WP_064368656.1\|3108774_3109665_+	hypothetical protein	R9TRQ4	Vibrio_phage	7.5e-90	57.5
WP_154205146.1\|3109658_3110132_+	DNA-binding protein	R9TPX7	Vibrio_phage	1.5e-36	55.8
WP_154205147.1\|3110128_3111769_+	hypothetical protein	A0A160DHT6	Vibrio_phage	3.3e-208	65.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage