CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP045999	Escherichia coli strain 1916D18 plasmid p1916D18-2, complete sequence	0 crisprs	NA	0	5
NZ_CP046000	Escherichia coli strain 1916D18 chromosome, complete genome	7 crisprs	csa3,PD-DExK,WYL,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,RT,DEDDh,DinG,c2c9_V-U4	10	8
NZ_CP045998	Escherichia coli strain 1916D18 plasmid p1916D18-1, complete sequence	0 crisprs	NA	0	1

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 7560

Xanthomonas_phage(100.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_063073481.1\|1523_6794_+	conjugative transfer relaxase/helicase TraI	NA	NA	NA	NA
WP_063073482.1\|6813_7560_+	type-F conjugative transfer system pilin acetylase TraX	A0A077JBM8	Xanthomonas_phage	3.3e-06	29.7

DBSCAN-SWA_2

17887 : 38467

Salmonella_phage(37.5%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_154139459.1\|17887_20854_-\|transposase	Tn3-like element TnAs1 family transposase	A0A1B0V7H9	Salmonella_phage	0.0e+00	99.9
WP_001161490.1\|20857_21418_-	recombinase family protein	A0A1B0V7I5	Salmonella_phage	1.1e-59	100.0
WP_001513488.1\|21727_23305_+	PAS domain-containing protein	A0A1B0V854	Salmonella_phage	1.2e-95	99.4
WP_062894229.1\|23549_23834_+	ribbon-helix-helix protein, CopG family	NA	NA	NA	NA
WP_063073486.1\|23833_24109_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_096320939.1\|25392_26666_-\|transposase	IS3 family transposase	Q9ZXG3	Shigella_phage	4.4e-168	94.4
WP_033804283.1\|27174_28311_+	porin	Q1MVN1	Enterobacteria_phage	8.3e-118	56.6
WP_000401034.1\|28406_30104_+	sulfatase-like hydrolase/transferase	A0A1V0SA98	Catovirus	2.0e-06	23.2
WP_001032733.1\|30172_30430_+	hypothetical protein	NA	NA	NA	NA
WP_099145072.1\|31528_32691_-\|transposase	IS3-like element IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	3.1e-51	40.6
WP_063073396.1\|34390_38467_-	autotransporter outer membrane beta-barrel domain-containing protein	Q9LA54	Enterobacteria_phage	4.3e-265	43.1

DBSCAN-SWA_3

41757 : 53687

Escherichia_phage(66.67%)

integrase,transposase

attL 26381:26395|attR 46523:46537

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
26381:26395	attL	NA	NA	NA	NA
WP_020219156.1\|41757_42564_+\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	1.1e-55	96.5
WP_085948178.1\|42638_43851_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_074440817.1\|44095_44791_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	1.5e-117	88.0
WP_000019440.1\|46176_47157_-\|transposase	IS5-like element ISKpn26 family transposase	A0A077SK28	Escherichia_phage	6.8e-185	99.1
46523:46537	attR	NA	NA	NA	NA
WP_085948178.1\|49113_50326_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_085947917.1\|52414_53687_+\|transposase	IS3-like element IS2 family transposase	Q9ZXG3	Shigella_phage	1.4e-177	99.3

DBSCAN-SWA_4

57264 : 62685

Macacine_betaherpesvirus(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001066942.1\|57264_58005_+	site-specific recombinase	I3WFA4	Macacine_betaherpesvirus	2.0e-24	57.6
WP_000361612.1\|58289_59267_-	RepB family plasmid replication initiator protein	J9Q7H0	Salmonella_phage	3.9e-100	59.2
WP_089533208.1\|60441_61083_-	hypothetical protein	NA	NA	NA	NA
WP_000019440.1\|61704_62685_-\|transposase	IS5-like element ISKpn26 family transposase	A0A077SK28	Escherichia_phage	6.8e-185	99.1

DBSCAN-SWA_5

69708 : 76317

Escherichia_phage(50.0%)

integrase,transposase

attL 69250:69262|attR 73687:73699

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
69250:69262	attL	NA	NA	NA	NA
WP_154139461.1\|69708_70413_-\|transposase	IS6 family transposase	A0A077SL39	Escherichia_phage	6.4e-137	98.7
WP_001707302.1\|70478_70910_+	hypothetical protein	NA	NA	NA	NA
WP_000016494.1\|70906_71698_+\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	9.4e-52	91.1
WP_050858693.1\|71849_72125_-	hypothetical protein	NA	NA	NA	NA
WP_000633913.1\|72118_72763_-	AAA family ATPase	A0A222YXS3	Escherichia_phage	1.9e-39	43.0
WP_001103690.1\|72991_73963_+	hypothetical protein	A0A222YXF2	Escherichia_phage	7.4e-67	42.9
73687:73699	attR	NA	NA	NA	NA
WP_063073471.1\|73967_74360_+	plasmid stability protein	NA	NA	NA	NA
WP_000109071.1\|75634_76072_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	8.3e-26	48.4
WP_001775014.1\|76068_76317_-	DinI-like family protein	Q2A098	Sodalis_phage	6.4e-15	49.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP046000

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP046000_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP046000_1

650113-650230

Orphan

Consensus_repeat	Method
TGCCGGATGCGATGCTGGCGCACCTTATCCGGCCTACGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP046000_1

>merge|NZ_CP046000|1|650113-650230|CRISPRCasFinder
TGCCGGATGCGATGCTGGCGCACCTTATCCGGCCTACGGGGTGCTCAACTTGTTGATGTTGTTGTGTTTTGTACCTGATGCCGGATGCGATGCTGGCGCATCTTATCCGGCCTACGGG

>NZ_CP046000|1|1|650113-650230|CRISPRCasFinder
TGCCGGATGCGATGCTGGCGCACCTTATCCGGCCTACGGG	GTGCTCAACTTGTTGATGTTGTTGTGTTTTGTACCTGA
TGCCGGATGCGATGCTGGCGCATCTTATCCGGCCTACGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046000.1\|WP_000096086.1\|655133_655433_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372871
NZ_CP046000.1\|WP_000531193.1\|653499_654486_-\|glutathione-S-transferase-family-protein	unknown	unknown	gnl\|CDD\|223512
NZ_CP046000.1\|WP_000548347.1\|639404_640394_+\|bifunctional-threonine-ammonia-lyase/L-serine-ammonia-lyase-TdcB	unknown	unknown	gnl\|CDD\|236317
NZ_CP046000.1\|WP_000861734.1\|643014_645309_+\|2-ketobutyrate-formate-lyase/pyruvate-formate-lyase	unknown	unknown	gnl\|CDD\|153087
NZ_CP046000.1\|WP_000104211.1\|638367_639306_+\|transcriptional-regulator-TdcA	unknown	unknown	gnl\|CDD\|182391
NZ_CP046000.1\|WP_000145836.1\|637834_638179_-\|DNA-binding-transcriptional-activator-TdcR	unknown	unknown	gnl\|CDD\|236909
NZ_CP046000.1\|WP_000401598.1\|647422_648754_+\|HAAAP-family-serine/threonine-permease	unknown	unknown	gnl\|CDD\|273283
NZ_CP046000.1\|WP_000622115.1\|645783_647148_+\|L-serine-ammonia-lyase	unknown	unknown	gnl\|CDD\|185000
NZ_CP046000.1\|WP_000719990.1\|645322_645712_+\|enamine/imine-deaminase	unknown	unknown	gnl\|CDD\|105214
NZ_CP046000.1\|WP_001297162.1\|641772_642981_+\|propionate-kinase	unknown	unknown	gnl\|CDD\|183484
NZ_CP046000.1\|WP_001297155.1\|654555_655038_-\|DoxX-family-protein	unknown	unknown	gnl\|CDD\|225168
NZ_CP046000.1\|WP_000384145.1\|652841_653207_-\|DUF805-domain-containing-protein	unknown	unknown	gnl\|CDD\|225694
NZ_CP046000.1\|WP_000031415.1\|655829_656135_-\|DUF883-domain-containing-protein	unknown	unknown	gnl\|CDD\|226941
NZ_CP046000.1\|WP_001198780.1\|652243_652600_-\|DUF805-domain-containing-protein	unknown	unknown	gnl\|CDD\|225694
NZ_CP046000.1\|WP_000785722.1\|655422_655827_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227681
NZ_CP046000.1\|WP_000107720.1\|640415_641747_+\|threonine/serine-transporter-TdcC	unknown	unknown	gnl\|CDD\|184191
NZ_CP046000.1\|WP_001041010.1\|651296_652193_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176122
NZ_CP046000.1\|WP_000460519.1\|648781_650092_+\|serine-dehydratase-subunit-alpha-family-protein	unknown	unknown	gnl\|CDD\|226206
NZ_CP046000.1\|WP_025650708.1\|650460_651192_-\|pirin-family-protein	unknown	unknown	gnl\|CDD\|224655
NZ_CP046000.1\|WP_001295544.1\|650303_650468_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP046000.1\|WP_000096086.1\|655133_655433_-\|hypothetical-protein	gnl\|CDD\|372871	pfam13997, YqjK, YqjK-like protein. The YqjK-like protein family includes the E. coli YqjK protein, which is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 100 amino acids in length. There is a single completely conserved residue R that may be functionally important.	6.11451e-20
NZ_CP046000.1\|WP_000531193.1\|653499_654486_-\|glutathione-S-transferase-family-protein	gnl\|CDD\|223512	COG0435, ECM4, Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones].	0
NZ_CP046000.1\|WP_000548347.1\|639404_640394_+\|bifunctional-threonine-ammonia-lyase/L-serine-ammonia-lyase-TdcB	gnl\|CDD\|236317	PRK08638, PRK08638, bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB.	0
NZ_CP046000.1\|WP_000861734.1\|643014_645309_+\|2-ketobutyrate-formate-lyase/pyruvate-formate-lyase	gnl\|CDD\|153087	cd01678, PFL1, Pyruvate formate lyase 1. Pyruvate formate lyase catalyzes a key step in anaerobic glycolysis, the conversion of pyruvate and CoenzymeA to formate and acetylCoA. The PFL mechanism involves an unusual radical cleavage of pyruvate in which two cysteines and one glycine form radicals that are required for catalysis. PFL has a ten-stranded alpha/beta barrel domain that is structurally similar to those of all three ribonucleotide reductase (RNR) classes as well as benzylsuccinate synthase and B12-independent glycerol dehydratase.	0
NZ_CP046000.1\|WP_000104211.1\|638367_639306_+\|transcriptional-regulator-TdcA	gnl\|CDD\|182391	PRK10341, PRK10341, transcriptional regulator TdcA.	0
NZ_CP046000.1\|WP_000145836.1\|637834_638179_-\|DNA-binding-transcriptional-activator-TdcR	gnl\|CDD\|236909	PRK11424, PRK11424, DNA-binding transcriptional activator TdcR; Provisional.	1.4676e-66
NZ_CP046000.1\|WP_000622115.1\|645783_647148_+\|L-serine-ammonia-lyase	gnl\|CDD\|185000	PRK15040, PRK15040, L-serine ammonia-lyase.	0
NZ_CP046000.1\|WP_000719990.1\|645322_645712_+\|enamine/imine-deaminase	gnl\|CDD\|105214	PRK11401, PRK11401, enamine/imine deaminase.	2.43767e-83
NZ_CP046000.1\|WP_001297162.1\|641772_642981_+\|propionate-kinase	gnl\|CDD\|183484	PRK12379, PRK12379, propionate kinase.	0
NZ_CP046000.1\|WP_001297155.1\|654555_655038_-\|DoxX-family-protein	gnl\|CDD\|225168	COG2259, COG2259, Predicted membrane protein [Function unknown].	2.8408e-29
NZ_CP046000.1\|WP_000384145.1\|652841_653207_-\|DUF805-domain-containing-protein	gnl\|CDD\|225694	COG3152, COG3152, Predicted membrane protein [Function unknown].	3.68376e-42
NZ_CP046000.1\|WP_000031415.1\|655829_656135_-\|DUF883-domain-containing-protein	gnl\|CDD\|226941	COG4575, ElaB, Uncharacterized conserved protein [Function unknown].	1.46625e-41
NZ_CP046000.1\|WP_001198780.1\|652243_652600_-\|DUF805-domain-containing-protein	gnl\|CDD\|225694	COG3152, COG3152, Predicted membrane protein [Function unknown].	1.64644e-35
NZ_CP046000.1\|WP_000785722.1\|655422_655827_-\|hypothetical-protein	gnl\|CDD\|227681	COG5393, COG5393, Predicted membrane protein [Function unknown].	2.73939e-60
NZ_CP046000.1\|WP_000107720.1\|640415_641747_+\|threonine/serine-transporter-TdcC	gnl\|CDD\|184191	PRK13629, PRK13629, threonine/serine transporter TdcC; Provisional.	0
NZ_CP046000.1\|WP_001041010.1\|651296_652193_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176122	cd08431, PBP2_HupR, The C-terminal substrate binding domain of LysR-type transcriptional regulator, HupR, which regulates expression of the heme uptake receptor HupA; contains the type 2 periplasmic binding fold. HupR, a member of the LysR family, activates hupA transcription under low-iron conditions in the presence of hemin. The expression of many iron-uptake genes, such as hupA, is regulated at the transcriptional level by iron and an iron-binding repressor protein called Fur (ferric uptake regulation). Under iron-abundant conditions with heme, the active Fur repressor protein represses transcription of the iron-uptake gene hupA, and prevents transcriptional activation via HupR. Under low-iron conditions with heme, the Fur repressor is inactive and transcription of the hupA is allowed. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.2986e-51
NZ_CP046000.1\|WP_000460519.1\|648781_650092_+\|serine-dehydratase-subunit-alpha-family-protein	gnl\|CDD\|226206	COG3681, COG3681, L-cysteine desulfidase [Amino acid transport and metabolism].	0
NZ_CP046000.1\|WP_025650708.1\|650460_651192_-\|pirin-family-protein	gnl\|CDD\|224655	COG1741, COG1741, Pirin-related protein [General function prediction only].	1.29754e-67
NZ_CP046000.1\|WP_000401598.1\|647422_648754_+\|HAAAP-family-serine/threonine-permease	gnl\|CDD\|273283	TIGR00814, membrane_transport_protein_YhjV, serine transporter. The Hydroxy/Aromatic Amino Acid Permease (HAAAP) Family- serine/threonine subfamily (TC 2.A.42.2) The HAAAP family includes well characterized aromatic amino acid:H+ symport permeases and hydroxy amino acid permeases. This subfamily is specific for hydroxy amino acid transporters and includes the serine permease, SdaC, of E. coli, and the threonine permease, TdcC, of E. coli.//added GO terms, none avaialbelf or ser/thr specifically [SS 2/6/05] [Transport and binding proteins, Amino acids, peptides and amines].	2.53913e-167

>NZ_CP046000.1|WP_000460519.1|648781_650092_+|serine-dehydratase-subunit-alpha-family-protein
MFDSTLNPLWQRYILAVQEEVKPALGCTEPISLALAAAVAAAELEGPVERVEAWVSPNLMKNGLGVTVPGTGMVGLPIAAALGALGGNANAGLEVLKDATAQAIADAKALLAAGKVSVKIQEPCNEILFSRAKVWNGEKWACVTIVGGHTNIVHIETHNGVVFTQQACVAEGEQESPLTVLSRTTLAEILKFVNEVPFAAIRFILDSAKLNCALSQEGLSGKWGLHIGATLEKQCERGLLAKDLSSSIVIRTSAASDARMGGATLPAMSNSGSGNQGITATMPVVVVAEHFGADDERLARALMLSHLSAIYIHNQLPRLSALCAATTAAMGAAAGMAWLVDGRYETISMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDTAVTGNEGIVAHDVEQSIANLCALASHSMQQTDRQIIEIMASKAR
>NZ_CP046000.1|WP_000401598.1|647422_648754_+|HAAAP-family-serine/threonine-permease
MEIASNKGVIADASTPAGRAGMSESEWREAIKFDSTDTGWVIMSIGMAIGAGIVFLPVQVGLMGLWVFLLSSVIGYPAMYLFQRLFINTLAESPECKDYPSVISGYLGKNWGILLGALYFVMLVIWMFVYSTAITNDSASYLHTFGVTEGLLSDSPFYGLVLICILVAISSRGEKLLFKISTGMVLTKLLVVAALGVSMVGMWHLYNVGSLPPLGLLVKNAIITLPFTLTSILFIQTLSPMVISYRSREKSIEVARHKALRAMNIAFGILFVTVFFYAVSFTLAMGHDEAVKAYEQNISALAIAAQFISGDGAAWVKVVSVILNIFAVMTAFFGVYLGFREATQGIVMNILRRKMPAEKINENLVQRGIMIFAILLAWSAIVLNAPVLSFTSICSPIFGMVGCLIPAWLVYKVPALHKYKGMSLYLIIVTGLLLCVSPFLAFS
>NZ_CP046000.1|WP_000622115.1|645783_647148_+|L-serine-ammonia-lyase
MISAFDIFKIGIGPSSSHTVGPMNAGKSFIDRLESSGLLTATSHIVVDLYGSLSLTGKGHATDVAIIMGLAGNSPQDVVIDEIPAFIELVTRSGRLPVASGAHIVDFPVAKNIIFHPEMLPRHENGMRITAWKGQEALLSKTYYSVGGGFIVEEEHFGLSHDVETSVPYDFHSAGELLKMCDYNGLSISGLMMHNELALRSKAEIDAGFARIWQVMHDGIERGMNTEGVLPGPLNVPRRAVALRRQLVSSDNISNDPMNVIDWINMYALAVSEENAAGGRVVTAPTNGACGIIPAVLAYYDKFRRPVNERSIARYFLAAGAIGALYKMNASISGAEVGCQGEIGVACSMAAAGLTELLGGSPAQVCNAAEIAMEHNLGLTCDPVAGQVQIPCIERNAINAVKAVNAARMAMRRTSAPRVSLDKVIETMYETGKDMNDKYRETSRGGLAIKVVCG
>NZ_CP046000.1|WP_000719990.1|645322_645712_+|enamine/imine-deaminase
MKKIIETQRAPGAIGPYVQGVDLGSMVFTSGQIPVCPQTGEIPADVQDQARLSLENVKAIVVAAGLSVGDIIKMTVFITDLNDFATINEVYKQFFDEHQATYPTRSCVQVARLPKDVKLEIEAIAVRSA
>NZ_CP046000.1|WP_000861734.1|643014_645309_+|2-ketobutyrate-formate-lyase/pyruvate-formate-lyase
MKVDIDTSDKLYADAWLGFKGTDWKNEINVRDFIQHNYTPYEGDESFLAEATPATTELWEKVMEGIRIENATHAPVDFDTNIATTITAHDAGYINQPLEKIVGLQTDAPLKRALHPFGGINMIKSSFHAYGREMDSEFEYLFTDLRKTHNQGVFDVYSPDMLRCRKSGVLTGLPDGYGRGRIIGDYRRVALYGISYLVRERELQFADLQSRLEKGEDLEATIRLREELAEHRHALLQIQEMAAKYGFDISRPAQNAQEAVQWLYFAYLAAVKSQNGGAMSLGRTASFLDIYIERDFKAGVLNEQQAQELIDHFIMKIRMVRFLRTPEFDSLFSGDPIWATEVIGGMGLDGRTLVTKNSFRYLHTLHTMGPAPEPNLTILWSEELPIAFKKYAAQVSIVTSSLQYENDDLMRTDFNSDDYAIACCVSPMVIGKQMQFFGARANLAKTLLYAINGGVDEKLKIQVGPKTAPLMDDVLDYDKVMDSLDHFMDWLAVQYISALNIIHYMHDKYSYEASLMALHDRDVYRTMACGIAGLSVATDSLSAIKYARVKPIRDENGLAVDFEIDGEYPQYGNNDERVDSIACDLVERFMKKIKALPTYRNAVPTQSILTITSNVVYGQKTGNTPDGRRAGTPFAPGANPMHGRDRKGAVASLTSVAKLPFTYAKDGISYTFSIVPAALGKEDPVRKTNLVGLLDGYFHHEADVEGGQHLNVNVMNREMLLDAIEHPEKYPNLTIRVSGYAVRFNALTREQQQDVISRTFTQAL
>NZ_CP046000.1|WP_001297162.1|641772_642981_+|propionate-kinase
MNEFPVVLVINCGSSSIKFSVLDASDCEVLMSGIADGINSENAFLSVNGGEPAPLAHHSYEGALKAIAFELEKRNLNDSVALIGHRIAHGGSIFTESAIITDEVIDNIRRVSPLAPLHNYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYLYGLPWKYYEELGVRRYGFHGTSHRYVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTRSGDVDFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLSSDLRVLEKAWHEGHERAQLAIKTFVHRIARHIAGHAASLRRLDGIIFTGGIGENSSLIRRLVMEHLAVLGVEIDTEMNNRSNSCGERIVSSENARVICAVIPTNEEKMIALDAIHLGKVNAPAEFA
>NZ_CP046000.1|WP_000107720.1|640415_641747_+|threonine/serine-transporter-TdcC
MSTSDSIVSSQTKQSSWRKSDTTWTLGLFGTAIGAGVLFFPIRAGFGGLIPILLMLVLAYPIAFYCHRALARLCLSGSNPSGNITETVEEHFGKTGGVVITFLYFFAICPLLWIYGVTITNTFMTFWENQLGFAPLNRGFVALFLLLLMAFVIWFGKDLMVKVMSYLVWPFIASLVLISLSLIPYWNSAVIDQVDLGSLSLTGHDGILITVWLGISIMVFSFNFSPIVSSFVVSKREEYEKDFGRDFTERKCSQIISRASMLMVAVVMFFAFSCLFTLSPANMAEAKAQNIPVLSYLANHFASMTGTKTTFAITLEYAASIIALVAIFKSFFGHYLGTLEGLNGLILKFGYKGDKTKVSLGKLNTISMIFIMGSTWVVAYANPNILDLIEAMGAPIIASLLCLLPMYAIRKAPSLAKYRGRLDNVFVTVIGLLTILNIVYKLF
>NZ_CP046000.1|WP_000548347.1|639404_640394_+|bifunctional-threonine-ammonia-lyase/L-serine-ammonia-lyase-TdcB
MHITYDLPVAIDDIIEAKQRLAGRIYKTGMPRSNYFSERCKGEIFLKFENMQRTGSFKIRGAFNKLSSLTDAEKRKGVVACSAGNHAQGVSLSCAMLGIDGKVVMPKGAPKSKVAATCDYSAEVVLHGDNFNDTIAKVSEIVEMEGRIFIPPYDDPKVIAGQGTIGLEIMEDLYDVDNVIVPIGGGGLIAGIAVAIKSINPTIRVIGVQSENVHGMAASFHSGEITTHRTTGTLADGCDVSRPGNLTYEIVRELVDDIVLVSEDEIRNSMIALIQRNKVVTEGAGALACAALLSGKLDQYIQNRKTVSIISGGNIDLSRVSQITGFVDA
>NZ_CP046000.1|WP_000104211.1|638367_639306_+|transcriptional-regulator-TdcA
MSTILLPKTQHLVVFQEVIRSGSIGSAAKELGLTQPAVSKIINDIEDYFGVELVVRKNTGVTLTPAGQLLLSRSESITREMKNMVNEISGMSSEAVVEVSFGFPSLIGFTFMSGMINKFKEVFPKAQVSMYEAQLSSFLPAIRDGRLDFAIGTLSAEMKLQDLHVEPLFESEFVLVASKSRTCTGTTTLESLKNEQWVLPQTNMGYYSELLTTLQRNGISIENIVKTDSVVTIYNLVLNADFLTVIPCDMTSPFGSNQFITIPVEETLPVAQYAAVWSKNYRIKKAASVLVELAKEYSSYNGCRRRQLIEVG
>NZ_CP046000.1|WP_000145836.1|637834_638179_-|DNA-binding-transcriptional-activator-TdcR
MTGITIFYGDNIIRYVVNTKKGLRPYFKQLPDNYQAKFELNLMSKFSNFIINKPFSAINTAARHIFSRYLLENKHLFYQYFKISNTGIDHLEQLINVNFFSSDRTSFCECNRFP
>NZ_CP046000.1|WP_001295544.1|650303_650468_-|hypothetical-protein
MSKKSAKKRQPVKPVVAKEPARTAKNFGYEEMLSELEAIVADAETRLAEDEATA
>NZ_CP046000.1|WP_025650708.1|650460_651192_-|pirin-family-protein
MITTRTARQCGQADYGWLQARYTFSFGHYFDPKLLGYASLRVLNQEVLAPGAAFQPRTYPKVDILNVILDGEAEYRDSEGNHVQASAGEALLLSTQPGVSYSEHNLSKDKPLTRMQLWLDACPQRENPLIQKLALNMGKQQLIASPEGTMGSLQLRQQVWLHHIVLDKGESANFQLHGPRAYLQSIHGKFHALTHHEEKAALTCGDGAFIRDEANITLVADSPLRALLIDLPVQLFLQGDDDE
>NZ_CP046000.1|WP_001041010.1|651296_652193_+|LysR-family-transcriptional-regulator
MAKERALTLEALRVMDAIDRRGSFAAAADELGRVPSALSYTMQKLEEELDVVLFDRSGHRTKFTNVGRMLLERGRVLLEAADKLTTDAEALARGWETHLTIVTEALVPTPAFFPLIDKLAAKANTQLAIITEVLAGAWERLEQGRADIVIAPDMHFRSSSEINSRKLYTLMNVYVAAPDHPIHQEPEPLSEVTRVKYRGIAVADTARERPVLTVQLLDKQPRLTVSTIEDKRQALLAGLGVATMPYPMVEKDIAEGRLRVVSPESTSEIDIIMAWRRDSMGEAKSWCLREIPKLFSGK
>NZ_CP046000.1|WP_001198780.1|652243_652600_-|DUF805-domain-containing-protein
MQWYLAVLKNYVGFSGRARRKEYWMFTLINAIVGAIINVIQLILGLEFPFLSLIYLAATIIPVIALCVRRLHDTDRSGAWALLYLVPIIGWLVLFVFACLEGNSGSNRYGNDPKFGSN
>NZ_CP046000.1|WP_000384145.1|652841_653207_-|DUF805-domain-containing-protein
MDWYLKVLKNYVGFRGRARRKEYWMFILVNIIFTFVLGLLDKMLGWQRAGGEGILTTIYGILVFLPWWAVQFRRLHDTDRSAWWALLFLIPFIGWLIIIVFNCQAGTPGENRFGPDPKLEP
>NZ_CP046000.1|WP_000531193.1|653499_654486_-|glutathione-S-transferase-family-protein
MGQLIDGVWHDTWYDTKSTGGKFQRSASAFRNWLTADGAPGPTGTGGFIAEKDRYHLYISLACPWAHRTLIMRKLKGLEPFISVSVVNPLMLENGWTFDDSFPGATGDTLYQHEFLYQLYLHADPHYSGRVTVPVLWDKKNHTIVSNESAEIIRMFNTAFDALGAKAGDYYPPALQTKIDELNGWIYDTVNNGVYKAGFATSQQAYDEAVAKVFESLARLEQILGQHRYLTGNQLTEADIRLWTTLVRFDPVYVTHFKCDKHRISDYLNLYGFLRDIYQMPGIAETVNFDHIRNHYFRSHKTINPTGIISIGPWQDLDEPHGRDVRFG
>NZ_CP046000.1|WP_001297155.1|654555_655038_-|DoxX-family-protein
MILSIDSNDANTAPLHKKTISSLSGAVESMMKKLEDVGVLVARILMPILFITAGWGKITAYSGTQQYMEAMGVPGFMLPLVILLEFGGGLAILFGFLTRTTALFTAGFTLLTAFLFHSNFAEGVNSLMFMKNLTISGGFLLLAITGPGAYSIDRLLNKKW
>NZ_CP046000.1|WP_000096086.1|655133_655433_-|hypothetical-protein
MSSKVERERRKAQLLSQIQQQRLDLSASRREWLEATGAYDRRWNMLLSLRSWALVGSSVMAIWTIRHPNMLVRWARRGFGVWSAWRLVKTTLKQQQLRG
>NZ_CP046000.1|WP_000785722.1|655422_655827_-|hypothetical-protein
MADTHHAQGPGKSVLGIGQRIVSIMVEMVETRLRLAVVELEEEKANLFQLLLMLGLTMLFAAFGLMSLMVLIIWAVDPQYRLNAMIATTVVLLLLALIGGIWTLRKSRKSTLLRHTRHELANDRQLLEEESREQ
>NZ_CP046000.1|WP_000031415.1|655829_656135_-|DUF883-domain-containing-protein
MSKEHTTEHLRAELKSLSDTLEEVLSSSGEKSKEELSKIRSKAEQALKQSRYRLGETGDAIAKQTRVAAARADEYVRENPWTGVGIGAAIGVVLGVLLSRR

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Crispr_ID: NZ_CP046000_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP046000_2

1067592-1067864

Unclear

I-E

Consensus_repeat	Method
GTGTTCCCCGCGCCAGCGGGGATAAACCG	PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRT

4 spacers

The CRISPR arrays of NZ_CP046000_2

>merge|NZ_CP046000|2|1067592-1067864|PILER-CR,CRISPRCasFinder,CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCGCCGATCACACGCTCCCACGGGCCGTACCAGTCGTGTTCCCCGCGCCAGAGGGGATAAACCGATGATTTTTGCACGACGTTCAACCGGCGTTTCGTGTTCCCCGCGCCAGCGGGGATAAACCGATCTAACGGAGTTAATCTTATCCGACTTTTTGGTGTTCCCCGCGCCAGCGGGGATAAACCGGACGCCGCCGCCGCGAAGCCGTTTCCGATGTTGAGTTCCCCGCGCCAGCGGGGATAAACCA

>NZ_CP046000|2|1|1067592-1067803|PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCGATCACACGCTCCCACGGGCCGTACCAGTC
GTGTTCCCCGCGCCAGAGGGGATAAACCG	ATGATTTTTGCACGACGTTCAACCGGCGTTTC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATCTAACGGAGTTAATCTTATCCGACTTTTTG
GTGTTCCCCGCGCCAGCGGGGATAAACCG

>NZ_CP046000|2|2|1067592-1067864|CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCGATCACACGCTCCCACGGGCCGTACCAGTC
GTGTTCCCCGCGCCAGAGGGGATAAACCG	ATGATTTTTGCACGACGTTCAACCGGCGTTTC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATCTAACGGAGTTAATCTTATCCGACTTTTTG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GACGCCGCCGCCGCGAAGCCGTTTCCGATGTT
GAGTTCCCCGCGCCAGCGGGGATAAACCA

>NZ_CP046000|2|1|1067592-1067864|CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCGATCACACGCTCCCACGGGCCGTACCAGTC
GTGTTCCCCGCGCCAGAGGGGATAAACCG	ATGATTTTTGCACGACGTTCAACCGGCGTTTC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATCTAACGGAGTTAATCTTATCCGACTTTTTG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GACGCCGCCGCCGCGAAGCCGTTTCCGATGTT
GAGTTCCCCGCGCCAGCGGGGATAAACCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046000.1\|WP_000046814.1\|1055559_1056861_+\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl\|CDD\|237291
NZ_CP046000.1\|WP_000581937.1\|1059220_1059469_+\|type-II-toxin-antitoxin-system-antitoxin-MazE	unknown	unknown	gnl\|CDD\|182082
NZ_CP046000.1\|WP_001164561.1\|1070007_1071285_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|349949
NZ_CP046000.1\|WP_000036723.1\|1062618_1063917_+\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NZ_CP046000.1\|WP_001299097.1\|1076097_1076958_+\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	unknown	unknown	gnl\|CDD\|224936
NZ_CP046000.1\|WP_000021323.1\|1071603_1072389_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187605
NZ_CP046000.1\|WP_001071648.1\|1059874_1060666_+\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569
NZ_CP046000.1\|WP_001098105.1\|1074006_1075344_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340929
NZ_CP046000.1\|WP_000059312.1\|1072458_1073913_+\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223354
NZ_CP046000.1\|WP_001130266.1\|1077105_1077681_-\|glycerol-3-phosphate-responsive-antiterminator	unknown	unknown	gnl\|CDD\|224865
NZ_CP046000.1\|WP_001324445.1\|1075321_1076101_+\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	unknown	unknown	gnl\|CDD\|224997
NZ_CP046000.1\|WP_001326096.1\|1077948_1079220_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|182194
NZ_CP046000.1\|WP_000254738.1\|1059468_1059804_+\|endoribonuclease-MazF	unknown	unknown	gnl\|CDD\|182138
NZ_CP046000.1\|WP_000547316.1\|1064041_1065370_+\|IS4-like-element-IS4-family-transposase	unknown	unknown	gnl\|CDD\|379017
NZ_CP046000.1\|WP_000226815.1\|1056908_1059143_+\|GTP-pyrophosphokinase	unknown	unknown	gnl\|CDD\|182797
NZ_CP046000.1\|WP_000109367.1\|1077697_1077958_-\|ferredoxin-family-protein	unknown	unknown	gnl\|CDD\|225289
NZ_CP046000.1\|WP_000039749.1\|1068502_1069981_-\|sugar-kinase	unknown	unknown	gnl\|CDD\|212662
NZ_CP046000.1\|WP_001288227.1\|1066301_1066442_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046000.1\|WP_025652447.1\|1065415_1066288_-\|YgcG-family-protein	unknown	unknown	gnl\|CDD\|224429
NZ_CP046000.1\|WP_000210878.1\|1060893_1062531_+\|CTP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|235437

Protein	Function_ID	Function_description	E-value
NZ_CP046000.1\|WP_000046814.1\|1055559_1056861_+\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl\|CDD\|237291	PRK13168, rumA, 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD.	0
NZ_CP046000.1\|WP_000581937.1\|1059220_1059469_+\|type-II-toxin-antitoxin-system-antitoxin-MazE	gnl\|CDD\|182082	PRK09798, PRK09798, MazF-MazE toxin-antitoxin system antitoxin MazE.	6.19513e-48
NZ_CP046000.1\|WP_001324445.1\|1075321_1076101_+\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	gnl\|CDD\|224997	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion].	7.46503e-62
NZ_CP046000.1\|WP_001164561.1\|1070007_1071285_-\|MFS-transporter	gnl\|CDD\|349949	cd06174, MFS, Major Facilitator Superfamily. The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate, while symporters and antiporters transport two substrates in the same or in opposite directions, respectively, across membranes. MFS proteins are typically 400 to 600 amino acids in length, and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members, GlpT (glycerol-3-phosphate transporter), LacY (lactose permease), and EmrD (multidrug transporter), MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake, and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4, which is impaired in type II diabetes, and glucose-6-phosphate transporter (G6PT), which causes glycogen storage disease when mutated.	4.09704e-29
NZ_CP046000.1\|WP_001299097.1\|1076097_1076958_+\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	gnl\|CDD\|224936	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion].	7.42017e-90
NZ_CP046000.1\|WP_000021323.1\|1071603_1072389_+\|SDR-family-oxidoreductase	gnl\|CDD\|187605	cd05347, Ga5DH-like_SDR_c, gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs. Ga5DH catalyzes the NADP-dependent conversion of carbon source D-gluconate and 5-keto-D-gluconate. This SDR subgroup has a classical Gly-rich NAD(P)-binding motif and a conserved active site tetrad pattern. However, it has been proposed that Arg104 (Streptococcus suis Ga5DH numbering), as well as an active site Ca2+, play a critical role in catalysis. In addition to Ga5DHs this subgroup contains Erwinia chrysanthemi KduD which is involved in pectin degradation, and is a putative 2,5-diketo-3-deoxygluconate dehydrogenase. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107,15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	2.28606e-139
NZ_CP046000.1\|WP_001071648.1\|1059874_1060666_+\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	8.97718e-160
NZ_CP046000.1\|WP_001098105.1\|1074006_1075344_+\|MFS-transporter	gnl\|CDD\|340929	cd17371, MFS_MucK, Cis,cis-muconate transport protein and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Acinetobacter sp. Cis,cis-muconate transport protein (MucK), Escherichia coli putative sialic acid transporter 1, and similar proteins. MucK functions in the uptake of muconate and allows Acinetobacter calcoaceticus ADP1 (BD413) to grow on exogenous cis,cis-muconate as the sole carbon source. The MucK subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.74708e-50
NZ_CP046000.1\|WP_000059312.1\|1072458_1073913_+\|FAD-binding-oxidoreductase	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	1.25325e-82
NZ_CP046000.1\|WP_001130266.1\|1077105_1077681_-\|glycerol-3-phosphate-responsive-antiterminator	gnl\|CDD\|224865	COG1954, GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription].	5.83077e-88
NZ_CP046000.1\|WP_001326096.1\|1077948_1079220_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|182194	PRK10015, PRK10015, oxidoreductase; Provisional.	3.18278e-125
NZ_CP046000.1\|WP_000254738.1\|1059468_1059804_+\|endoribonuclease-MazF	gnl\|CDD\|182138	PRK09907, PRK09907, endoribonuclease MazF.	1.17475e-74
NZ_CP046000.1\|WP_000547316.1\|1064041_1065370_+\|IS4-like-element-IS4-family-transposase	gnl\|CDD\|379017	pfam13006, Nterm_IS4, Insertion element 4 transposase N-terminal. This family represents the N-terminal region of proteins carrying the transposase enzyme, DDE_Tnp_1 (that was Transposase_11), pfam01609, at the C-terminus. The full-length members are Insertion Element 4, IS4. Within the collection of E.coli strains, ECOR, the number of IS4 elements varies from zero to 14, with an average of 5 copies/strain.	8.73403e-38
NZ_CP046000.1\|WP_000226815.1\|1056908_1059143_+\|GTP-pyrophosphokinase	gnl\|CDD\|182797	PRK10872, relA, (p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional.	0
NZ_CP046000.1\|WP_000109367.1\|1077697_1077958_-\|ferredoxin-family-protein	gnl\|CDD\|225289	COG2440, FixX, Ferredoxin-like protein [Energy production and conversion].	8.55479e-42
NZ_CP046000.1\|WP_000039749.1\|1068502_1069981_-\|sugar-kinase	gnl\|CDD\|212662	cd07779, FGGY_ygcE_like, uncharacterized ygcE-like proteins. This subfamily consists of uncharacterized hypothetical bacterial proteins with similarity to Escherichia coli sugar kinase ygcE , whose functional roles are not yet clear. Escherichia coli ygcE is recognized by this model, but is not present in the alignment as it contains a deletion relative to other members of the group. These proteins belong to the FGGY family of carbohydrate kinases, the monomers of which contain two large domains, which are separated by a deep cleft that forms the active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain.	5.32002e-110
NZ_CP046000.1\|WP_000210878.1\|1060893_1062531_+\|CTP-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NZ_CP046000.1\|WP_025652447.1\|1065415_1066288_-\|YgcG-family-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	8.16409e-100
NZ_CP046000.1\|WP_000036723.1\|1062618_1063917_+\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0

>NZ_CP046000.1|WP_001288227.1|1066301_1066442_-|hypothetical-protein
MSEENKENGFNHVKTFTKIIFIFSVLVFNDNESKITDAAVNLFIQI
>NZ_CP046000.1|WP_025652447.1|1065415_1066288_-|YgcG-family-protein
MRYFILMFTFVCSFVAAQPTIVPQLQQQVTDLTSSLNSQEKKELTHKLDSIFNNTQVQIAVLIVPTTKDETIEQYATRVFDNWRLGDAKRNDGILIIVAWSDRTVRIQVGYGLEEKVTDALAGDIIRSNMIPAFKQQKFAQGLELAINALNNQLTSQHQYPTNPSESESASSSDHYYFAIFWVFAVMFFPFWFFHQGSNFCRACKSGVYISAIYLLDLFLFSDKIFSIGVFSFFFTFTIFMVFTCLCVLQKRASGKSYHSDNSGSGGGSSGGGFSGGGGSSGGGGASGRW
>NZ_CP046000.1|WP_000547316.1|1064041_1065370_+|IS4-like-element-IS4-family-transposase
MHIGQALDLVSRYDSLRNPLTSLGDYLDPELISRCLAESGTVTLRKRRLPLEMMVWCIVGMALERKEPLHQIVNRLDIMLPGNRPFVAPSAVIQARQRLGSEAVRRVFTKTAQLWHNATPHPQWCGLTLLAIDGVFWRTPDTPENDAAFPRQTHAGNPALYPQVKMVCQMELTSHLLTAAAFGTMKNSENELAEQLIEQTGDNTLTLMDKGYYSLGLLNAWSLAGEHRHWMIPLRKGAQYEEIRKLGKGDHLVKLKTSPQARKKWPGLGNEVTARLLTVTRKGKVCHLLTSMTDAMRFPGGEMADLYSHRWEIELGYREIKQTMQLSRLTLRSKKPELVEQELWGVLLAYNLVRYQMIKMAEHLKGYWPNQLSFSESCGMVMRMLMTLQGASPGRIPELMHDLASMGQLVKLPTRRERAFPRVVKERPWKYPTAPKKSQSVA
>NZ_CP046000.1|WP_000036723.1|1062618_1063917_+|phosphopyruvate-hydratase
MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>NZ_CP046000.1|WP_000210878.1|1060893_1062531_+|CTP-synthase-(glutamine-hydrolyzing)
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK
>NZ_CP046000.1|WP_001071648.1|1059874_1060666_+|nucleoside-triphosphate-pyrophosphohydrolase
MNQIDRLLTIMQRLRDPENGCPWDKEQTFATIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFADSSAENSSEVLARWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWTTLGPVVDKVYEEIDEVMYEARQAVVDQAKLEEEMGDLLFATVNLARHLGTKAEIALQKANEKFERRFREVERIVAARGLEMTGVDLETMEEVWQQVKRQEIDL
>NZ_CP046000.1|WP_000254738.1|1059468_1059804_+|endoribonuclease-MazF
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
>NZ_CP046000.1|WP_000581937.1|1059220_1059469_+|type-II-toxin-antitoxin-system-antitoxin-MazE
MIHSSVKRWGNSPAVRIPATLMQALNLNIDDEVKIDLVDGKLIIEPVRKEPVFTLAELVNDITPENLHENIDWGEPKDKEVW
>NZ_CP046000.1|WP_000226815.1|1056908_1059143_+|GTP-pyrophosphokinase
MVAVRSAHINKAGEFDPEKWIASLGITSQKSCECLAETWAYCLQQTQGHPDASLLLWRGVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKSVVNLIHGVRDMAAIRQLKATHTDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHLREVKDAPEDERVLAAKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPTEYKRIAKLLHERRLDREHYIEEFVGHLRAEMKAEGVKAEVYGRPKHIYSIWRKMQKKNLAFDELFDVRAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTVEIQIRTKQMHEDAELGVAAHWKYKEGAAAGGARSGHEDRIAWLRKLIAWQEEMADSGEMLDEVRSQVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGDQIEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAGRQILDDELEHLGISLKEAEKHLLPRYNFNDVDELLAAIGGGDIRLNQMVNFLQSQFNKPSAEEQDAAALKQLQQKSYTPQNRSKDNGRVVVEGVGNLMHHIARCCQPIPGDEIVGFITQGRGISVHRADCEQLAELRSHAPERIVDAVWGESYSAGYSLVVRVVANDRSGLLRDITTILANEKVNVLGVASRSDTKQQLATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARRLHGS
>NZ_CP046000.1|WP_000046814.1|1055559_1056861_+|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MAQFYSAKRRTTTRQIITVSVNDLDSFGQGVARHNGKTLFIPGLLPQENAEVTVTEDKKQYARAKVVRRLSDSPERETPRCPHFGVCGGCQQQHASVDLQQRSKSAALARLMKHDVSEVIADVPWGYRRRARLSLNYLPKTQQLQMGFRKAGSSDIVDVKQCPILAPQLEALQPKVRACLGSLQAMRHLGHVELVQATSGTLMILRHTAPLSSADREKLERFSHSEGLDLYLAPDSEILETVSGEMPWYDSNGLRLTFSPRDFIQVNAGVNQKMVARALEWLDVQPEDRVLDLFCGMGNFTLPLATQAASVVGVEGVPALVEKGQQNARLNGLQNVTFYHENLEEDVTKQPWAKNGFDKVLLDPARAGAAGVMQQIIKLEPIRIVYVSCNPATLARDSEALLKAGYTIARLAMLDMFPHTGHLESMVLFSRVK
>NZ_CP046000.1|WP_000039749.1|1068502_1069981_-|sugar-kinase
MSKKYIIGIDGGSQSTKVVMYDLEGNVVCEGKGLLQPMHTPYADTAEHPDDDLWASLCFAGHDLMSQFAGNKEDIVGIGLGSIRCCRALLKADGTPAAPLISWQDARVTRPYEHTNPDVAYVTSFSGYLTHRLTGEFKDNIANYFGQWPVDYKSRAWSEDAAVMDKFNIPRHMLFDVQMPGTVLGHITPQAALATHFPAGLPVVCTTSDKPVEALGAGLLDDETAVISLGTYIALMMNGKALPKDPVAYWPIMSSIPQTLLYEGYGIRKGMWTVSWLRDMLGESLIQDARAQDLSPEDLLNKKASSVPPGCNGLMTVLDWLTNPWEPYKRGIMIGFDSSMDYAWIYRSILESVALTLKNNYDNMCNEMNHFAKHVIITGGGSNSDLFMQIFADVFNLPARRNAINGCASLGAAINTAVGLGLYPDYATAVDKMVRVKDIFIPIESNAKRYDAMNKGIFKDLTKHTDVILKKSYEVMHGELGNVDSIQSWSNA
>NZ_CP046000.1|WP_001164561.1|1070007_1071285_-|MFS-transporter
MQHNSYRRWITLAIISFSGGVSFDLAYLRYIYQIPMAKFMGFSNTEIGLIMSTFGIAAIILYAPSGVIADKFSHRKMITSAMIITGLLGLLMATYPPLWVMLCIQVAFAITTILMLWSVSIKAASLLGDHSEQGKIMGWMEGLRGVGVMSLAVFTMWVFSRFAPDDSASLKTVIIIYSVVYILLGILCWFFVSDNNNLRSANNEEKQSFQLSDILAVLRISTTWYCSMVIFGVFTIYAILSYSTNYLTEMYGMSLVAASYMGIAINKIFRALCGPLGGIITTYSKVKSPTRVIQILSVLGLLALTALLVTNSNPQSVAMGIGLILLLGFTCYASRGLYWACPGEARTPSYIMGTTVGICSVIGFLPDVFVYPIIGHWQDTLPAAEAYRNMWLMGMAALAMVIVFTFLLFQKIRTADSAPAMASSK
>NZ_CP046000.1|WP_000021323.1|1071603_1072389_+|SDR-family-oxidoreductase
MSIESLNAFSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANIFIPSFVKDNGETKEMIEKQGVEVDFMQVDITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAYCDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVLEHIPANRWGDTQDLMGAAVFLASPASNYVNGHLLVVDGGYLVR
>NZ_CP046000.1|WP_000059312.1|1072458_1073913_+|FAD-binding-oxidoreductase
MSLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHGIYTLPIPAAVVKLGSTEQVSRVLNFMNAHKINGVPRTGASATEGGLETVVENSVVLDGSAMNQIINIDIENMQATAQCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRSIGQFSTLYGAIEDMVVGLEAVLADGTVTRIKNVPRRAAGPDIRHIIIGNEGALCYITEVTVKIFKFTPENNLFYGYILEDMKTGFNILREVMVEGYRPSIARLYDAEDGTQHFTHFADGKCVLIFMAEGNPRIAKATGEGIAEIVARYPQCQRVDSKLIETWFNNLNWGPDKVAAERVQILKTGNMGFTTEVSGCWSCIHEIYESVINRIRTEFPHADDITMLGGHSSHSYQNGTNMYFVYDYNVVDCKPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWSKLEHGSAWALLEGLKKQFDPNGIMNTGTIYPIEK
>NZ_CP046000.1|WP_001098105.1|1074006_1075344_+|MFS-transporter
MNTSPVRMDDLPLNRFHCRIAALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWISDHIGRQKIFTFSFLLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGYVLASIAGHHFISENPEAWRWLLASAALPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVVTATHKHIKTLFSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLGLVLTHLLAHRKFLLGSFLLLAATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQVTLLLLATVLLVGFVVTWLWAPETKALPLVAAGNVGGANEHSVSV
>NZ_CP046000.1|WP_001324445.1|1075321_1076101_+|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein
MNILLAFKAEPDAGMLAEKEWQAAAQGKSGPDISLLRSLLGADEQAAAALLLAQRKNGTPMSLTALSMGDERALHWLRYLMALGFEEAVLLETAADLRFAPEFVARHIAEWQHQNPLDLIITGCQSSEGQNGQTPFLLAEMLGWPCFTQVERFTLDALFITLEQRTEHGLRCCRVRLPAVIAVRQCGEVALPVPGMRQRMAAGKAEIIRKTVAAEMPAMQCLQLARAEQRRGATLIDGQTVAEKAQKLWRDYLRQRMQP
>NZ_CP046000.1|WP_001299097.1|1076097_1076958_+|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein
MNIAIVTINQENAAIASWLAAQDFSGCTLAHWQIEPQPVVAEQVLDALVEQWQRTPADVVLFPPGTFGDELSTRLAWRLHGASICQVTSLDIPTVSVRKSHWGNALTATLQTEKRPLCLSLARQAGAAKNATLPSGMQQLNIVPGALPDWLVSTEDLKNVTRDPLAEARRVLVVGQGGEADNQEIAMLAEKLGAEVGYSRARVMNGGVDAEKVIGISGHLLAPEVCIVVGASGAAALMAGVRNSKFVVAINHDASAAVFSQADVGVVDDWKVVLEALVTNIHADCQ
>NZ_CP046000.1|WP_001130266.1|1077105_1077681_-|glycerol-3-phosphate-responsive-antiterminator
MPLLHLLRQNPVIAAVKDNASLQLAIDSECQFISVLYGNICTISNIVKKIKNAGKYAFIHVDLLEGASNKEVVIQFLKLVTEADGIISTKASMLKAARAEGFFCIHRLFIVDSISFHNIDKQVAQSNPDCIEILPGCMPKVLGWVTEKIRQPLIAGGLVCDEEDARNAINAGVVALSTTNTGVWTLAKKLL
>NZ_CP046000.1|WP_000109367.1|1077697_1077958_-|ferredoxin-family-protein
MSVAHNLWRVADAPHIVPADSVERQMVQRLINACPAGLFSLTPEGDLRVDYHGCLECGTCRLLCDESTLQQWRYPPSGFGITYRFG
>NZ_CP046000.1|WP_001326096.1|1077948_1079220_-|FAD-dependent-oxidoreductase
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQFHLTAPLERRITHESLSLLTPDGATTFSSLQPGGESWSVLRARFDPWLVAEAEKEGVECIPGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVLAERHGLVTRPAGEAMALGIKEVLSLETSAIEERFHLENNEGAALLFSGGICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQSRVPASELLTRFKAHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDALRSCVNTGISVRGMDMALTGAQAAAQTLISACQHREPQNLFPLYHHNVERSLLWDVLQRYQHVPALLQRPGWYRVWPALMQDISRDLWDQGDKPVPPLRQLFWRHLRRHGLWHLAGDVIRSLRCL

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Crispr_ID: NZ_CP046000_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP046000_3

1093582-1094587

TypeI-E

I-E

Consensus_repeat	Method
GTGTTCCCCGCGCCAGCGGGGATAAACCG	PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRT

16 spacers

cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of NZ_CP046000_3

>merge|NZ_CP046000|3|1093582-1094587|PILER-CR,CRISPRCasFinder,CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCGATTAACGCGGCCCGCCTCTGCGTTGGCGTGAAGTGTTCCCCGCGCCAGCGGGGATAAACCGCGCGTTTCTGGAACCGTAATTTGCTGCGGTATGTGTTCCCCGCGCCAGCGGGGATAAACCGCTATTGGCCTCACTGCCACCGCAGTTAATACTGTGTTCCCCGCGCCAGCGGGGATAAACCGGAATATCGGGTGCCAGCCTGGACGCTGGCCGAGTGTTCCCCGCGCCAGCGGGGATAAACCGACGCGAATCGGCGGTTTTGAGCGGGTAGCAAAGTGTTCCCCGCGCCAGCGGGGATAAACCGGAATATCGGGTGCCAGCCTGGACGCTGGCCGAGTGTTCCCCGCGCCAGCGGGGATAAACCGACGCGAATCGGCGGTTTTGAGCGGGTAGCAAAGTGTTCCCCGCGCCAGCGGGGATAAACCGCTCCGCTCTGTGTTCGATAAACTCATCCAGCAGTGTTCCCCGCGCCAGCGGGGATAAACCGAATTAAAATCCCCGTTTCTGTTACATGGGCGAGTGTTCCCCGCGCCAGCGGGGATAAACCGAATTTTCTTCATTGCTCAAACAGGCTGCATAACGTGTTCCCCGCGCCAGCGGGGATAAACCGACGAAAATCGCCGCCGGTGTCCTCGCTGATCAGTGTTCCCCGCGCCAGCGGGGATAAACCGGACTCAACCGCGCTTCCCGGCCTCACCACTGCGTGTTCCCCGCGCCAGCGGGGATAAACCGGCGAAAAAATACGGCTGGATGCGACAAAAAAAGTGTTCCCCGCGCCAGCGGGGATAAACCGCCAAAGAAGAACAACGAGCCAACTGGTTTCAGGTGTTCCCCGCGCCAGCGGGGATAAACCGGCAATTTGTTGTCCGCGATCCGGTACGCGCGTGTGTTCCCCGCGCCAGCGGGGATAAACCGCGGCTATGGAATTTATGGAGAAGTTTGGTTTTGTGTTCCCCGCGCCAGCGGGGATAAACCG

>NZ_CP046000|3|2|1093582-1094587|PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATTAACGCGGCCCGCCTCTGCGTTGGCGTGAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGCGTTTCTGGAACCGTAATTTGCTGCGGTAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CTATTGGCCTCACTGCCACCGCAGTTAATACT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GAATATCGGGTGCCAGCCTGGACGCTGGCCGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGCGAATCGGCGGTTTTGAGCGGGTAGCAAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GAATATCGGGTGCCAGCCTGGACGCTGGCCGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGCGAATCGGCGGTTTTGAGCGGGTAGCAAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CTCCGCTCTGTGTTCGATAAACTCATCCAGCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AATTAAAATCCCCGTTTCTGTTACATGGGCGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AATTTTCTTCATTGCTCAAACAGGCTGCATAAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGAAAATCGCCGCCGGTGTCCTCGCTGATCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GACTCAACCGCGCTTCCCGGCCTCACCACTGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCGAAAAAATACGGCTGGATGCGACAAAAAAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCAAAGAAGAACAACGAGCCAACTGGTTTCAG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCAATTTGTTGTCCGCGATCCGGTACGCGCGT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGGCTATGGAATTTATGGAGAAGTTTGGTTTT
GTGTTCCCCGCGCCAGCGGGGATAAACCG

>NZ_CP046000|3|3|1093582-1094587|CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATTAACGCGGCCCGCCTCTGCGTTGGCGTGAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGCGTTTCTGGAACCGTAATTTGCTGCGGTAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CTATTGGCCTCACTGCCACCGCAGTTAATACT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GAATATCGGGTGCCAGCCTGGACGCTGGCCGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGCGAATCGGCGGTTTTGAGCGGGTAGCAAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GAATATCGGGTGCCAGCCTGGACGCTGGCCGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGCGAATCGGCGGTTTTGAGCGGGTAGCAAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CTCCGCTCTGTGTTCGATAAACTCATCCAGCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AATTAAAATCCCCGTTTCTGTTACATGGGCGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AATTTTCTTCATTGCTCAAACAGGCTGCATAAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGAAAATCGCCGCCGGTGTCCTCGCTGATCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GACTCAACCGCGCTTCCCGGCCTCACCACTGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCGAAAAAATACGGCTGGATGCGACAAAAAAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCAAAGAAGAACAACGAGCCAACTGGTTTCAG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCAATTTGTTGTCCGCGATCCGGTACGCGCGT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGGCTATGGAATTTATGGAGAAGTTTGGTTTT
GTGTTCCCCGCGCCAGCGGGGATAAACCG

>NZ_CP046000|3|2|1093582-1094587|CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATTAACGCGGCCCGCCTCTGCGTTGGCGTGAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGCGTTTCTGGAACCGTAATTTGCTGCGGTAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CTATTGGCCTCACTGCCACCGCAGTTAATACT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GAATATCGGGTGCCAGCCTGGACGCTGGCCGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGCGAATCGGCGGTTTTGAGCGGGTAGCAAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GAATATCGGGTGCCAGCCTGGACGCTGGCCGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGCGAATCGGCGGTTTTGAGCGGGTAGCAAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CTCCGCTCTGTGTTCGATAAACTCATCCAGCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AATTAAAATCCCCGTTTCTGTTACATGGGCGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AATTTTCTTCATTGCTCAAACAGGCTGCATAAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGAAAATCGCCGCCGGTGTCCTCGCTGATCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GACTCAACCGCGCTTCCCGGCCTCACCACTGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCGAAAAAATACGGCTGGATGCGACAAAAAAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCAAAGAAGAACAACGAGCCAACTGGTTTCAG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCAATTTGTTGTCCGCGATCCGGTACGCGCGT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGGCTATGGAATTTATGGAGAAGTTTGGTTTT
GTGTTCCCCGCGCCAGCGGGGATAAACCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046000.1\|WP_000206406.1\|1089812_1090886_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	cd09646_cas7_CAS-I-E	gnl\|CDD\|273843
NZ_CP046000.1\|WP_000372392.1\|1095957_1096866_+\|sulfate-adenylyltransferase-subunit-CysD	unknown	unknown	gnl\|CDD\|235375
NZ_CP046000.1\|WP_000039843.1\|1083563_1084298_+\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NZ_CP046000.1\|WP_000517476.1\|1099466_1099778_+\|cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156
NZ_CP046000.1\|WP_001246104.1\|1098949_1099273_+\|DUF3561-family-protein	unknown	unknown	gnl\|CDD\|371891
NZ_CP046000.1\|WP_000281442.1\|1091624_1092275_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09664_cas6e_CAS-I-E	gnl\|CDD\|273869
NZ_CP046000.1\|WP_000085068.1\|1090896_1091643_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776
NZ_CP046000.1\|WP_001290706.1\|1081777_1083490_+\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	unknown	unknown	gnl\|CDD\|237402
NZ_CP046000.1\|WP_001295182.1\|1102012_1102774_+\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
NZ_CP046000.1\|WP_000029313.1\|1089264_1089798_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09670_cse2gr11_CAS-I-E	gnl\|CDD\|274193
NZ_CP046000.1\|WP_000956458.1\|1084562_1084715_+\|type-I-toxin-antitoxin-system-Hok-family-toxin	unknown	unknown	gnl\|CDD\|366840
NZ_CP046000.1\|WP_000490402.1\|1094668_1095706_-\|aminopeptidase	unknown	unknown	gnl\|CDD\|182299
NZ_CP046000.1\|WP_001090383.1\|1096867_1098295_+\|sulfate-adenylyltransferase-subunit-CysN	unknown	unknown	gnl\|CDD\|235349
NZ_CP046000.1\|WP_000568943.1\|1100982_1102032_+\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884
NZ_CP046000.1\|WP_001233958.1\|1084908_1087608_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP046000.1\|WP_001173673.1\|1098294_1098900_+\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
NZ_CP046000.1\|WP_154139498.1\|1092271_1093192_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NZ_CP046000.1\|WP_001084087.1\|1087705_1089268_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
NZ_CP046000.1\|WP_000246138.1\|1099796_1100507_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
NZ_CP046000.1\|WP_001219242.1\|1100506_1100986_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851

Protein	Function_ID	Function_description	E-value
NZ_CP046000.1\|WP_000206406.1\|1089812_1090886_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	1.07534e-147
NZ_CP046000.1\|WP_000372392.1\|1095957_1096866_+\|sulfate-adenylyltransferase-subunit-CysD	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
NZ_CP046000.1\|WP_000039843.1\|1083563_1084298_+\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	7.99311e-138
NZ_CP046000.1\|WP_000517476.1\|1099466_1099778_+\|cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	5.55235e-62
NZ_CP046000.1\|WP_001246104.1\|1098949_1099273_+\|DUF3561-family-protein	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	1.22003e-52
NZ_CP046000.1\|WP_000281442.1\|1091624_1092275_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|273869	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1974 from Chlorobium tepidum, is found in the Ecoli subtype of CRISPR/Cas regions and is designated Cse3 (CRISPR/Cas Subtype Ecoli protein 3). The representative of this family from Thermus thermophilus HB8 (TTHB192) has been crystallized and found to have a structure consisting of two domains with opposing parallel beta-sheets known as a beta-sheet platform. This structure is similar to those found in the Sex-lethal protein and poly(A)-binding protein. This structure is consistent with an RNA-binding function.	7.04911e-92
NZ_CP046000.1\|WP_000085068.1\|1090896_1091643_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	4.95914e-49
NZ_CP046000.1\|WP_001290706.1\|1081777_1083490_+\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	gnl\|CDD\|237402	PRK13504, PRK13504, NADPH-dependent assimilatory sulfite reductase hemoprotein subunit.	0
NZ_CP046000.1\|WP_001295182.1\|1102012_1102774_+\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.92279e-150
NZ_CP046000.1\|WP_000029313.1\|1089264_1089798_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|274193	TIGR02548, CRISPR_system_Cascade_subunit_CasB, CRISPR type I-E/ECOLI-associated protein CasB/Cse2. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It was designated Cse2 originally, and renamed CasB based on its characterization in the CASCADE complex.	2.05058e-29
NZ_CP046000.1\|WP_000956458.1\|1084562_1084715_+\|type-I-toxin-antitoxin-system-Hok-family-toxin	gnl\|CDD\|366840	pfam01848, HOK_GEF, Hok/gef family.	8.32243e-12
NZ_CP046000.1\|WP_000490402.1\|1094668_1095706_-\|aminopeptidase	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
NZ_CP046000.1\|WP_001090383.1\|1096867_1098295_+\|sulfate-adenylyltransferase-subunit-CysN	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
NZ_CP046000.1\|WP_000568943.1\|1100982_1102032_+\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0
NZ_CP046000.1\|WP_001233958.1\|1084908_1087608_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	5.43534e-176
NZ_CP046000.1\|WP_001173673.1\|1098294_1098900_+\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	7.34447e-148
NZ_CP046000.1\|WP_154139498.1\|1092271_1093192_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	5.09678e-157
NZ_CP046000.1\|WP_001084087.1\|1087705_1089268_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	4.91562e-166
NZ_CP046000.1\|WP_000246138.1\|1099796_1100507_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	3.26939e-121
NZ_CP046000.1\|WP_001219242.1\|1100506_1100986_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	1.56248e-104

>NZ_CP046000.1|WP_154139498.1|1092271_1093192_+|type-I-E-CRISPR-associated-endonuclease-Cas1
MTFVPLSPIPLKDRTSMIFLQYGQIDVLDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVHLAATVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQAKLALTEDLRLKVVRKMYELRFREPQPARRSVEQLRGIEGSRVRQTYALLAKQYGVKWNGRKYDPKDWEKGDVVNRCISAATSCLYGISEAAVLAAGYAPAIGFIHSGKPLSFVYDIADIIKFDSVVPKAFEIAARQPAEPDKEVRLACRDIFRSTKLTGKLIPLIEEVLAAGEIEPPQPAPDMLPPAIPEPEMLGDSGHRGRG
>NZ_CP046000.1|WP_000281442.1|1091624_1092275_+|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSRITLHTGQLSPAQLLHLVDRGEYVMHQWLWDLFPGGKERQFLYRREELQGAFRFFVLSQERPAESDTFTIECRSFAPELCTGQQLCFNLRANPTICKAGKRHDLLMEAKRQVRGQAEGSDVWLHQQQAALDWLAAQGERSGFTLLDTSVDAYRQQQLRRENSRQLIQFSSVDYTGMLTVTDPGLFVQRLSQGYGKSRAFGCGLMLIKPGAEA
>NZ_CP046000.1|WP_000085068.1|1090896_1091643_+|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSQYLIFQLHGPMASWGVDAPGEVRHTHELPSRSALLGLLAAGVGIRRDDTERLNAFNRHYSLVVCASRNPRWARDYHTVQMPKEVRKARYFSRREELSDPELLSAIISRRDYYTDAWWMVAVATTADAPYSLEQLQDGLRHPVFPLYLGRKSHPLALPLAPLLLEGNACDALCNAYQQYQDHFHKLKVSLPKLQDECWWEGKHDGLVASKILRRRDVPLNRQQWLFGERTVNQGPWLSKEEPCTSQE
>NZ_CP046000.1|WP_000206406.1|1089812_1090886_+|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTFIQLHLLTAYPAANLNRDDSGSPKTVILGGATRLRVSSQSLKRAWRTSELFEQALAGHIGVRSGRIAREAATILIEKGIEDKKAIEWAVEIADYLGKAKKDKKQKNDKKPKDPLTSAETEQLVHISPAEFDAVKALAHQLAEEKRAPKEKDLALLRKDRMAVDIAMFGRMLAKKPGFNVEAACQVAHAFGVSETIVENDFFTAVDDLRQASEDAGAGHVDETGFGSALFYTYICIDKDLLVENLGGDEALANQTIRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTDQPRSLAAAFYEPINGTRQLDVAVQRITTLRENMNTVYEQKTECASFDVMNKQGSMKDVLDFICA
>NZ_CP046000.1|WP_000029313.1|1089264_1089798_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSIVKDEHKVALRKWHEELQDKRGERASLRRSTTVNDVCLTDGFRLFLKNRQIKWQDEPEWRITALALIAAVSANVKAIDERQPFAAQLAAVMKKGRFTRLLAVKTPDDLLRQLRRAVKLLNGSVNLDSLAEGVFRWCQESDDLLNHHRRQQRPTEFIRIRWALEYYQAGDADNEQN
>NZ_CP046000.1|WP_001084087.1|1087705_1089268_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MNSFSLLTTPWLPVRFKDGTTGKLAPVDLADENVVDIAAPRADLQGAAWQFLLGLLQTSFAPKDQRRWDDIWEDGLEAEKLREALLSLEHAFQFGPDSPSFMQDFDELKVKATSIASLLPDAPGKQTKERNTDHFIKRDTTQHLCLHCVPLALFSIQLNAPIGGRGYYPGLRGGGPLTTLIELLEYQGNQQTPLWRKLWLNVMPQDEADLPLPKTFDDLVFPWLAPTRTSELDGAVVTDEQVNKLQAYWGMPRRIRIDFKTTSIGNCDICGRQSDALLGLMSLKNYGVQYVMWRHPLTPYRLPLKEGGDFYSVKPQPGGLIWRDWLGLIEVGNSKNNTELPAQVVKLLNASNLKQTRVGLWGFGFDFEDMKVRCWYEHHFPLLLNKKEDLIPKLRLAAQAASHILSLLHRALKEAWFSEKKTTKLDFGFVDIDFWNKTQHRFLRLVRKIEEGQDPYELLSKWQKEMWLFARQDFDDRVFTNPYEPVDLERVMTARKKYFTTSAEKQNANAAREKKQEAAE
>NZ_CP046000.1|WP_001233958.1|1084908_1087608_+|CRISPR-associated-helicase/endonuclease-Cas3
MRKYPLSLLKDKNIVTFFDFWGKTRRGEKDGGDDYHLLCWHSLDVAAMGYLMVKRNCFGLADYFRQLGISDKEQAAQFFAWLLCWHDIGKFARSFQQLYLPPELKIQESARKNYEKISHSTLGYWLWNHYLSECQELLPSSSLSPRKLRRVIEMWMPVTTGHHGRPPDRMDELDNFLPEDKAAARDFLLAIKALFPRIEIPAFWDDDEGIELIKHLSWYISATVVLADWTGSSTRFFPRVAQAMDIKHYWQKALVQAQNALTVFPPKAETAPFTGINTLFPFIENPTPLQQKVLDLDISQPGPQLFILEDVTGAGKTEAALILAHRLIAAGKAQGLFFGLPTMATANAMYDRLVKTWLSFYSPESRPSLVLAHSARTLMDRFNESLWSGDLIGSEEPDEQAFSQGCAAWFADSNKKALLAEIGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAYMSCILEGLIERQARGGNSVILLSATLSQQQRDKLVAAFARGAEGQQEAPLLGKDDYPWLTHVTKTDVHSHRVATRKEVERSVSVGWLHSEQECIARIESAVSQGKCIAWIRNSVDDAIQVYRQLLARGVIPASSLSLFHSRFAFSDRQRIETETLARFGKYCSLQRASQVIVCTQVIEQSVDIDLDEMISDLAPIDLLIQRAGRLQRHIRDINGQLKRDGKDERSPPELLILAPVWDDAPGDEWFGSAMRNSAYVYPDHGRIWLTQRVLREQGAIQMPHAARLLIESVYGEDVVMPEGFARSEQEQVGKYYCDRARAKKYVLNFRPGYAANINDYLPEKLSTRLAEESVSLWLATCIDGVVKPYATGAHAWEMSVVRVRRSWWKKHRDEFSLLEGDAFRQWCVEQRQDPEMANVILVTDDESCGYSAREGLIGKVG
>NZ_CP046000.1|WP_000956458.1|1084562_1084715_+|type-I-toxin-antitoxin-system-Hok-family-toxin
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK
>NZ_CP046000.1|WP_000039843.1|1083563_1084298_+|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIHPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMSEEETRFFGLKRECGLHEG
>NZ_CP046000.1|WP_001290706.1|1081777_1083490_+|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit
MSEKHPGPLVVEGKLTDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTKQWQAIDKFAGENTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDDNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHKGDFRITANQNLIIAGVPESEKAKIEKIAKESGLMNAVTPQRENSMACVSFPTCPLAMAEAERFLPSFIDNIDNLMAKHGVSDEHIVMRVTGCPNGCGRAMLAEVGLVGKAPGRYNLHLGGNRIGTRIPRMYKENITEPEILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDLWD
>NZ_CP046000.1|WP_000490402.1|1094668_1095706_-|aminopeptidase
MFSALRHRTAALALGVCFILPVHASSPKPGDFANTQARHIATFFPGRMTGTPAEMLSADYIRQQFQQMGYRSDIRTFNSRYIYTARDNRKNWHNVTGSTVIAAHEGKAPQQIIIMAHLDTYAPLSDADADANLGGLTLQGMDDNAAGLGVMLELAERLKNTPTEYGIRFVATSGEEEGKLGAENLLKRMSDTEKKNTLLVINLDNLIVGDKLYFNSGVKTPEAVRKLTRDRALAIARSHGIAATTNPGLNKNYPKGTGCCNDAEIFDKAGIAVLSVEATNWNLGNKDGYQQRAKTAAFPAGNSWHDVRLDNQQHIDKALPGRIERRCRDVMRIMLPLVKELAKAS
>NZ_CP046000.1|WP_000372392.1|1095957_1096866_+|sulfate-adenylyltransferase-subunit-CysD
MDQKRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
>NZ_CP046000.1|WP_001090383.1|1096867_1098295_+|sulfate-adenylyltransferase-subunit-CysN
MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYSEETFTRIRKDYLTFAEQLPGNLDIRFVPLSALEGDNVASQSESMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARVDGIRYQVDINNLTQREVENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAAPSEFSAFELELNALVRRHFPHWGARDLLGDK
>NZ_CP046000.1|WP_001173673.1|1098294_1098900_+|adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
>NZ_CP046000.1|WP_001246104.1|1098949_1099273_+|DUF3561-family-protein
MRNSHNITLTNNDSLTEDEETTWSLPGAVVGFISWLFALAMPMLIYGSNTLFFFIYTWPFFLALMPVAVVVGIALHSLMDGKLRYSIVFTLVTVGIMFGALFMWLLG
>NZ_CP046000.1|WP_000517476.1|1099466_1099778_+|cell-division-protein-FtsB
MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNAKLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNNR
>NZ_CP046000.1|WP_000246138.1|1099796_1100507_+|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHALLAHPRVKRVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKAAGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQENT
>NZ_CP046000.1|WP_001219242.1|1100506_1100986_+|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
>NZ_CP046000.1|WP_000568943.1|1100982_1102032_+|tRNA-pseudouridine(13)-synthase-TruD
MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHILVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLSAFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYFGAQRFGIGGSNLQGAQRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEELAELQRRVNDKELMITAALPGSGEWGTQREALAFEQAAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVVRELINTTGDYAHIAE
>NZ_CP046000.1|WP_001295182.1|1102012_1102774_+|5'/3'-nucleotidase-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINVPDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQDVVSDWLNSVGVGTQW

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Crispr_ID: NZ_CP046000_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP046000_4

2240586-2240709

Orphan

Consensus_repeat	Method
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP046000_4

>merge|NZ_CP046000|4|2240586-2240709|CRISPRCasFinder
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTACGGACGCAGGATGGTGCGTTCAATTGGACTCGAACCAACGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA

>NZ_CP046000|4|4|2240586-2240709|CRISPRCasFinder
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	CGGACGCAGGATGGTGCGTTCAATTGGACTCGAACCAA
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046000.1\|WP_000102278.1\|2249605_2249695_+\|stress-response-protein-YnhF	unknown	unknown	unknown
NZ_CP046000.1\|WP_000716922.1\|2238415_2240020_-\|FAD-NAD(P)-binding-protein	unknown	unknown	gnl\|CDD\|182134
NZ_CP046000.1\|WP_001070236.1\|2232673_2233300_+\|ferredoxin-like-protein	unknown	unknown	gnl\|CDD\|182135
NZ_CP046000.1\|WP_001182363.1\|2246028_2247240_-\|Bcr/CflA-family-multidrug-efflux-MFS-transporter	unknown	unknown	gnl\|CDD\|182924
NZ_CP046000.1\|WP_000190982.1\|2248281_2249307_-\|HTH-type-transcriptional-repressor-PurR	unknown	unknown	gnl\|CDD\|236739
NZ_CP046000.1\|WP_000007283.1\|2251175_2251757_-\|superoxide-dismutase-[Fe]	unknown	unknown	gnl\|CDD\|182534
NZ_CP046000.1\|WP_000528342.1\|2232008_2232218_+\|fumarate-hydratase-FumD	unknown	unknown	gnl\|CDD\|182359
NZ_CP046000.1\|WP_000534291.1\|2241023_2242280_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|137602
NZ_CP046000.1\|WP_001295403.1\|2230039_2231452_-\|pyruvate-kinase-I	unknown	unknown	gnl\|CDD\|181699
NZ_CP046000.1\|WP_000493947.1\|2243908_2244550_+\|riboflavin-synthase	unknown	unknown	gnl\|CDD\|183846
NZ_CP046000.1\|WP_154139512.1\|2233320_2235423_+\|aldehyde-ferredoxin-oxidoreductase	unknown	unknown	gnl\|CDD\|236629
NZ_CP046000.1\|WP_000504352.1\|2235426_2236074_+\|YdhW-family-putative-oxidoreductase-system-protein	unknown	unknown	gnl\|CDD\|182160
NZ_CP046000.1\|WP_000269501.1\|2247352_2248285_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182948
NZ_CP046000.1\|WP_000587554.1\|2237591_2238404_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182159
NZ_CP046000.1\|WP_001578429.1\|2249860_2251030_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|225371
NZ_CP046000.1\|WP_001349911.1\|2236137_2236806_+\|4Fe-4S-dicluster-domain-containing-protein	unknown	unknown	gnl\|CDD\|274451
NZ_CP046000.1\|WP_000098911.1\|2244589_2245738_-\|cyclopropane-fatty-acyl-phospholipid-synthase	unknown	unknown	gnl\|CDD\|183282
NZ_CP046000.1\|WP_001069986.1\|2236802_2237588_+\|thiosulfate-reductase-cytochrome-B-subunit	unknown	unknown	gnl\|CDD\|184968
NZ_CP046000.1\|WP_000212657.1\|2240145_2240451_-\|monooxygenase	unknown	unknown	gnl\|CDD\|182975
NZ_CP046000.1\|WP_001174942.1\|2242320_2243694_-\|multidrug-efflux-MATE-transporter-MdtK	unknown	unknown	gnl\|CDD\|234981

Protein	Function_ID	Function_description	E-value
NZ_CP046000.1\|WP_000716922.1\|2238415_2240020_-\|FAD-NAD(P)-binding-protein	gnl\|CDD\|182134	PRK09897, PRK09897, FAD-NAD(P)-binding protein.	0
NZ_CP046000.1\|WP_001070236.1\|2232673_2233300_+\|ferredoxin-like-protein	gnl\|CDD\|182135	PRK09898, PRK09898, ferredoxin-like protein.	6.18812e-139
NZ_CP046000.1\|WP_001182363.1\|2246028_2247240_-\|Bcr/CflA-family-multidrug-efflux-MFS-transporter	gnl\|CDD\|182924	PRK11043, PRK11043, Bcr/CflA family multidrug efflux MFS transporter.	0
NZ_CP046000.1\|WP_000190982.1\|2248281_2249307_-\|HTH-type-transcriptional-repressor-PurR	gnl\|CDD\|236739	PRK10703, PRK10703, HTH-type transcriptional repressor PurR.	0
NZ_CP046000.1\|WP_000007283.1\|2251175_2251757_-\|superoxide-dismutase-[Fe]	gnl\|CDD\|182534	PRK10543, PRK10543, superoxide dismutase [Fe].	3.77321e-138
NZ_CP046000.1\|WP_000528342.1\|2232008_2232218_+\|fumarate-hydratase-FumD	gnl\|CDD\|182359	PRK10292, PRK10292, fumarate hydratase FumD.	2.11502e-34
NZ_CP046000.1\|WP_000534291.1\|2241023_2242280_+\|hypothetical-protein	gnl\|CDD\|137602	PRK09945, PRK09945, hypothetical protein; Provisional.	0
NZ_CP046000.1\|WP_001295403.1\|2230039_2231452_-\|pyruvate-kinase-I	gnl\|CDD\|181699	PRK09206, PRK09206, pyruvate kinase PykF.	0
NZ_CP046000.1\|WP_000493947.1\|2243908_2244550_+\|riboflavin-synthase	gnl\|CDD\|183846	PRK13020, PRK13020, riboflavin synthase subunit alpha; Provisional.	2.24506e-123
NZ_CP046000.1\|WP_154139512.1\|2233320_2235423_+\|aldehyde-ferredoxin-oxidoreductase	gnl\|CDD\|236629	PRK09849, PRK09849, putative oxidoreductase; Provisional.	0
NZ_CP046000.1\|WP_000504352.1\|2235426_2236074_+\|YdhW-family-putative-oxidoreductase-system-protein	gnl\|CDD\|182160	PRK09947, PRK09947, YdhW family putative oxidoreductase system protein.	2.81741e-122
NZ_CP046000.1\|WP_000269501.1\|2247352_2248285_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|182948	PRK11074, PRK11074, putative DNA-binding transcriptional regulator; Provisional.	0
NZ_CP046000.1\|WP_000587554.1\|2237591_2238404_+\|hypothetical-protein	gnl\|CDD\|182159	PRK09946, PRK09946, hypothetical protein; Provisional.	6.15588e-175
NZ_CP046000.1\|WP_001578429.1\|2249860_2251030_+\|MFS-transporter	gnl\|CDD\|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	9.77318e-98
NZ_CP046000.1\|WP_001349911.1\|2236137_2236806_+\|4Fe-4S-dicluster-domain-containing-protein	gnl\|CDD\|274451	TIGR03149, cyt_nit_nrfC, cytochrome c nitrite reductase, Fe-S protein. Members of this protein family are the Fe-S protein, NrfC, of a cytochrome c nitrite reductase system for which the pentaheme cytochrome c protein, NrfB (family TIGR03146) is an unambiguous marker. Members of this protein family show similarity to other ferredoxin-like proteins, including a subunit of a polysulfide reductase. [Energy metabolism, Electron transport].	7.32003e-76
NZ_CP046000.1\|WP_000098911.1\|2244589_2245738_-\|cyclopropane-fatty-acyl-phospholipid-synthase	gnl\|CDD\|183282	PRK11705, PRK11705, cyclopropane fatty acyl phospholipid synthase.	0
NZ_CP046000.1\|WP_001069986.1\|2236802_2237588_+\|thiosulfate-reductase-cytochrome-B-subunit	gnl\|CDD\|184968	PRK15006, PRK15006, thiosulfate reductase cytochrome B subunit; Provisional.	4.08478e-163
NZ_CP046000.1\|WP_000212657.1\|2240145_2240451_-\|monooxygenase	gnl\|CDD\|182975	PRK11118, PRK11118, putative monooxygenase; Provisional.	1.12003e-64
NZ_CP046000.1\|WP_001174942.1\|2242320_2243694_-\|multidrug-efflux-MATE-transporter-MdtK	gnl\|CDD\|234981	PRK01766, PRK01766, multidrug efflux protein; Reviewed.	0

>NZ_CP046000.1|WP_000212657.1|2240145_2240451_-|monooxygenase
MATLLQLHFAFNGPFGDAMAEQLKPLAESINQEPGFLWKVWTESEKNHEAGGIYLFTDEKSALAYLEKHTARLKNLGVEEVVAKVFDVNEPLSQINQAKLA
>NZ_CP046000.1|WP_000716922.1|2238415_2240020_-|FAD-NAD(P)-binding-protein
MKKIAIVGAGPTGIYTLFSLLQQQTPLSISIFEQADEAGVGMPYSDEENSKMMLANIASIEIPPINCTYLEWLQKQEASHLQRYGVKKETLHDRQFLPRILLGEYFRDQFLRLVDQARQQKFAVAVYESCQVTDLQITNAGVMLATNQDLPSETFDLAVIATGHVWPDEEEATRTYFPSPWSGLMEAKVDACNVGIMGTSLSGLDAAMAVAIQHGSFIEDDKQHVVFNRDNASEKLNITLMSRTGILPEADFYCPIPYEPLHIVTDQALNAEIQKGEEGLLDRVFRLIVEEIKFADPDWSQRIALESLNVDSFAQAWFAERKQRDPFDWAEKNLQEVERNKREKHTVPWRYVILRLHEAVQEIVPHLNEHDHKRFSKGLARVFIDNYAAIPSESIRRLLALREAGIIHILALGEDYKMEINESRTVLKTEDNSYSFDVFIDARGQRPLKVKDIPFPGLREQLQKTGDEIPDVGEDYTLQQPEDIRGRVAFGALPWLMHDQPFVQGLTACAEIGEAMARAVVKPASRARRRLSFD
>NZ_CP046000.1|WP_000587554.1|2237591_2238404_+|hypothetical-protein
MIITRADLREWRIGAVMYRWFLRHFPRGGSYADIHHALIEEGYTDWAESLVEYAWKKWLADENFAHQEVSSMQKLATDPGEIPFCSQFARSDDHARIGCCEDNARIATAGYAAQIASMGYSVRIGSVGFNSHIGSSGERARVAVTGNSSRISSAGDSSRIANTGMRVRVCTLGERCHIASNGDLVQIASFGANARIANSGDNVHIIASGENSTVVSTGVVDSIILGPGGSAALAYHDGERVRFAVAIEGENNIRTGVRYRLNEQHQFVEC
>NZ_CP046000.1|WP_001069986.1|2236802_2237588_+|thiosulfate-reductase-cytochrome-B-subunit
MNPSQHAEQFQSQLANYVPQFTPEFWPVWLIIAGVLLVGMWLVLGLHALLRARGVKKSATDHGEKVYLYSKAVRLWHWSNALLFVLLLASGLINHFAMVGATAVKSLVAVHEVCGFLLLACWLGFVLINAVGDNGHHYRIRRQGWLERAAKQTRFYLFGIMQGEEHPFPATTQSKFNPLQQVAYVGVMYGLLPLLLLTGLLCLYPQAVGDVFPGVRYWLLQAHFALAFISLFFIFGHLYLCTTGRTPHETFKSMVDGYHRH
>NZ_CP046000.1|WP_001349911.1|2236137_2236806_+|4Fe-4S-dicluster-domain-containing-protein
MSFTRRKFVLGMGTVIFFTGSASSLLANTRQEKEVRYAMIHDESRCNGCNICARACRKTNHVPAQGSRLSIAHIPVTDNDNETQYHFFRQSCQHCEDAPCIDVCPTGASWRDEQGIVRVEKSQCIGCSYCIGACPYQVRYLNPVTKVADKCDFCAESRLAKGFPPICVSACPEHALIFGREDSPEIQAWLQDNKYYQYQLPGAGKPHLYRRFGQHLIKKENV
>NZ_CP046000.1|WP_000504352.1|2235426_2236074_+|YdhW-family-putative-oxidoreductase-system-protein
MGEMNHRDELPLAKVSEVDEAKRQWLQGMRHPVDTVTEPEPAEILAEFIRQHSAAGQLVARAVFLSPPYSVAEEELSVLLESIKQNGDYADIACMTGSQDDYYYSTQAMSENYAAMSLQVVEQDICRAIAHAVRFECQTYPRPYKVAMLMQAPYYFQEAQIEAAIAAMDVAPEYADIRQVESSTAVLYLFSERFMTYGKAYGLCEWFEVEQFQNP
>NZ_CP046000.1|WP_154139512.1|2233320_2235423_+|aldehyde-ferredoxin-oxidoreductase
MANGWTGNILRVNLTTGNITLEDSSKFKSFVGGMGFGYKIMYDEVPPGTKPFDEANKLVFATGPLTGSGAPCSSRVNITSLSTFTKGNLVVDAHMGGFFAAQMKFAGYDVIIIEGKAKSPVWLKIKDDKVSLEKADFLWGKGTRATTEEICRLTSPETCVAAIGQAGENLVPLSGMLNSRNHSGGAGTGAIMGSKNLKAIAVEGTKGVNIADRQEMKRLNDYMMTELIGANNNHVVPSTPQSWVEYSDPKSRWTARKGLFWGAAEGGPIETGEIPPGNQNTVGFRTYKSVFDLGPAAEKYTVKMSGCHSCPIRCMTQMNIPRVKEFGVPSTGGNTCVANFVHTTIFPNGPKDFEDKDDGRVIGNLVGLNLFDDYGLWCNYGQLHRDFTYCYSKGVFKRVLPAEEYAEIRWDQLEAGDVNFIKDFYYRLAHRVGELSHLADGSYAIAERWNLGEEYWGYAKNKLWSPFGYPVHHANEASAQVGSIVNCMFNRDCMTHTHINFIGSGLPLKLQREVAKELFGSEDAYDETKNYTPINDAKIKYAKWSLLRVCLHNAVTLCNWVWPMTVSPLKSRNYRGDLALEAKFFKAITGEEMTQEKLDLAAERIFTLHRAYTVKLMQTKDMRNEHDLICSWVFDKDPQIPVFTEGTDKMDRDDMHASLTMFYKEMGWDPQLGCPTRETLQRLGLEDIAADLAAHNLLPV
>NZ_CP046000.1|WP_001070236.1|2232673_2233300_+|ferredoxin-like-protein
MNPVDRPLLDIGLTRLEFLRISGKGLAGLTIAPALLSLLGCKQEDIDSGTVGLINTPKGVLVTQRARCTGCHRCEISCTNFNDGSVGTFFSRIKIHRNYFFGDNGVGSGGGLYGDLNYTADTCRQCKEPQCVNVCPIGAITWQQKEGCITVDHKRCIGCSACTTACPWMMATVNTESKKSSKCVLCGECANACPTGALKIIEWKDITV
>NZ_CP046000.1|WP_000528342.1|2232008_2232218_+|fumarate-hydratase-FumD
MGNRTKEDELYREMCRVVGKVVLEMRDLGQEPKHIVIAGVLRTALANKRIQRSELEKQAMETVINALVK
>NZ_CP046000.1|WP_001295403.1|2230039_2231452_-|pyruvate-kinase-I
MKKTKIVCTIGPKTESEEMLAKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMSKTGKTAAILLDTKGPEIRTMKLEGGNDVSLKAGQTFTFTTDKSVIGNSEMVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVIEIREHLKAHGGENIHIISKIENQEGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATICERTDRVMNSRLEFNNDNRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARAVRKYFPDATILALTTNEKTAHQLVLSKGVVPQLVKEITSTDDFYRLGKELALQSGLAHKGDVVVMVSGALVPSGTTNTASVHVL
>NZ_CP046000.1|WP_000534291.1|2241023_2242280_+|hypothetical-protein
MGSDAKNLMSDGNVQIVKTGEVIGATQLTEGELIVEAGGRAENTVVTGAGWLKVATGGIAKCTQYGNNGTLSVSDGAIATDIVQSEGGAISLSTLATVNGRHPEGEFSVDQGYACGLLLENGGNLRVLEGHRAEKIILDQEGGLLVNGTTSAVVVDEGGELLVYPGGEASNCEINQGGVFMLAGKASDTLLAGGTMNNLGGEDSDTIVENGSIYRLGTDGLQLYSSGKTQNLSVNVGGRAEVHAGTLENAVIQGGTVILLSPTSADENFVVEEDRAPVELTGSVALLDGASMIIGYGADLQQSTITVQQGGVLILDGSTVKGDGVTFIVGNINLNGGKLWLITGAATHVQLKVKRLRGEGAICLQTSAKEISPDFINVKGEVTGDIHVEITDASRQTLCNALKLQPDEDGIGATLQPA
>NZ_CP046000.1|WP_001174942.1|2242320_2243694_-|multidrug-efflux-MATE-transporter-MdtK
MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLIMLVLWNAGYIIRSMENIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSMRDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMMLRMRFLQRLPSVIILQRASR
>NZ_CP046000.1|WP_000493947.1|2243908_2244550_+|riboflavin-synthase
MFTGIVQGTAKLVSIDEKPNFRTHVVELPDHMLDGLETGASVAHNGCCLTVTEINGNHVSFDLMKETLRITNLGDLKVGDWVNVERAAKFSDEIGGHLMSGHIMTTAEVAKILTSENNRQIWFKVQDSQLMKYILYKGFIGIDGISLTVGEVTPTRFCVHLIPETLERTTLGKKKLGARVNIEIDPQTQAVVDTVERVLAARENAMNQPGTEA
>NZ_CP046000.1|WP_000098911.1|2244589_2245738_-|cyclopropane-fatty-acyl-phospholipid-synthase
MSSSCIEEVSVPDDNWYRIANELLSRAGIAINGSAPADIRVKNPDFFKRVLQEGSLGLGESYMDGWWECDRLDMFFSKVLRAGLENQLPHHFKDTLRIASARLFNLQSKKRAWIVGKEHYDLGNDLFSRMLDPFMQYSCAYWKDADNLESAQQAKLKMICEKLQLKPGMRVLDIGCGWGGLAHYMASNYDVSVVGVTISAEQQKMAQERCEGLDVTILLQDYRDLNDQFDRIVSVGMFEHVGPKNYDTYFAVVDRNLKPEGIFLLHTIGSKKTDLNVDPWINKYIFPNGCLPSVRQIAQSSEPHFVMEDWHNFGADYDTTLMAWYERFLAAWPEIADNYSERFKRMFTYYLNACAGAFRARDIQLWQVVFSRGVENGLRVAR
>NZ_CP046000.1|WP_001182363.1|2246028_2247240_-|Bcr/CflA-family-multidrug-efflux-MFS-transporter
MQPGKRFLVWLAGLSVLGFLATDMYLPAFAAIQADLQTPASAVSASLSLFLAGFAAAQLLWGPLSDRYGRKPVLLIGLTIFALGSLGMLWVENAATLLVLRFVQAVGVCAAAVIWQALVTDYYPSQKVNRIFATIMPLVGLSPALAPLLGSWLLVHFSWQAIFATLFAITVVLILPIFWLKPTTKARNNSQDGLTFTDLLRSKTYRGNVLIYAACSASFFAWLTGSPFILSEMGYSPAVIGLSYVPQTIAFLIGGYGCRAALQKWQGKQLLPWLLVLFAVSVIATWAAGFISHVSLVEILIPFCVMAIANGAIYPIVVAQALRPFPHATGRAAALQNTLQLGLCFLASLVVSWLISISTPLLTTTSVMLSTVVLVALGYMMQRCEEVGCQNHGNAEVAHSESH
>NZ_CP046000.1|WP_000269501.1|2247352_2248285_+|LysR-family-transcriptional-regulator
MWSEYSLEVVDAVARNGSFSAAAQELHRVPSAVSYTVRQLEEWLAVPLFERRHRDVELTAAGAWFLKEGRSVVKKMQITRQQCQQIANGWRGQLAIAVDNIVRPERTRQMIVDFYRHFDDVELLVFQEVFNGVWDALSDGRVELAIGATRAIPVGGRYAFRDMGMLSWSCVVASHHPLALMDGPFSDDTLRNWPSLVREDTSRTLPKRITWLLDNQKRVVVPDWESSATCISAGLCIGMVPTHFAKPWLNEGKWVALELENPFPDSACCLTWQQNDMSPALTWLLEYLGDSETLNKEWLREPEETPATGD
>NZ_CP046000.1|WP_000190982.1|2248281_2249307_-|HTH-type-transcriptional-repressor-PurR
MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYLSMMAQKRVDGLLVMCSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVIDNAFEGGYMAGRYLIERGHREIGVIPGPLERNTGAGRLAGFMKAMEEAMIKVPESWIVQGDFEPESGYRAMQQILSQPHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDNVRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREEPQSIEVHPRLIERRSVADGPFRDYRR
>NZ_CP046000.1|WP_000102278.1|2249605_2249695_+|stress-response-protein-YnhF
MSTDLKFSLVTTIIVLGLIVAVGLTAALH
>NZ_CP046000.1|WP_001578429.1|2249860_2251030_+|MFS-transporter
MKINYPLLALAIGAFGIGTTEFSPMGLLPVIARGVDVSIPAAGMLISAYAVGVMVGAPLMTLLLSHRARRSALIFLMAIFTLGNVLSAIAPDYMTLMLSRILTSLNHGAFFGLGSVVAASVVPKHKQASAVATMFMGLTLANIGGVPAATCLGETIGWRMSFLATAGLGVISMVSLFFSLPKGGAGARPEVKKELAVLMRPQVLSALLTTVLGAGAMFTLYTYISPVLQSITHATPVFVTAMLVLIGVGFSIGNYLGGKLADRSVNGTLKGFLLLLMVIMLAIPFLARNEFGAAISMVVWGAATFAVVPPLQMRVMRVASEAPGLSSSVNIGAFNLGNALGAAAGGAVISAGLGYSFVPVMGAIVAGLALLLVFMSARKQPETVCVANS
>NZ_CP046000.1|WP_000007283.1|2251175_2251757_-|superoxide-dismutase-[Fe]
MSFELPALPYAKDALAPHISAETIEYHYGKHHQTYVTNLNNLIKGTAFEGKSLEEIIRSSEGGVFNNAAQVWNHTFYWNCLAPNAGGEPTGKVAEAIAASFGSFADFKAQFTDAAIKNFGSGWTWLVKNSDGKLAIVSTSNAGTPLTTDATPLLTVDVWEHAYYIDYRNARPGYLEHFWALVNWEFVAKNLAA

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Crispr_ID: NZ_CP046000_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP046000_5

3175255-3175399

Orphan

Consensus_repeat	Method
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP046000_5

>merge|NZ_CP046000|5|3175255-3175399|CRISPRCasFinder
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGCTGCGAAAATGCCTTATCTGGCCTACAGATTCGATGCGATTCGTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGAATGC

>NZ_CP046000|5|5|3175255-3175399|CRISPRCasFinder
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGC	TGCGAAAATGCCTTATCTGGCCTACAGATTCGATGCGATTC
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGAATGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046000.1\|WP_000042533.1\|3165639_3167661_-\|excinuclease-ABC-subunit-B	unknown	unknown	gnl\|CDD\|235395
NZ_CP046000.1\|WP_001295301.1\|3163153_3164143_-\|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl\|CDD\|234672
NZ_CP046000.1\|WP_000951213.1\|3170802_3171843_-\|biotin-synthase-BioB	unknown	unknown	gnl\|CDD\|185063
NZ_CP046000.1\|WP_000679972.1\|3180611_3181565_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176131
NZ_CP046000.1\|WP_001295302.1\|3164539_3165448_+\|uridine-diphosphate-N-acetylglucosamine-binding-protein-YvcK	unknown	unknown	gnl\|CDD\|211689
NZ_CP046000.1\|WP_000593936.1\|3175422_3177684_-\|hydratase	unknown	unknown	gnl\|CDD\|183125
NZ_CP046000.1\|WP_000891685.1\|3183574_3184633_-\|molybdenum-ABC-transporter-ATP-binding-protein-ModC	unknown	unknown	gnl\|CDD\|182993
NZ_CP046000.1\|WP_001471254.1\|3169651_3170806_-\|8-amino-7-oxononanoate-synthase	unknown	unknown	gnl\|CDD\|235655
NZ_CP046000.1\|WP_000891515.1\|3186264_3186414_-\|multidrug-efflux-pump-associated-protein,-AcrZ-family	unknown	unknown	gnl\|CDD\|371231
NZ_CP046000.1\|WP_000213425.1\|3182755_3183574_+\|pyridoxal-phosphatase	unknown	unknown	gnl\|CDD\|182523
NZ_CP046000.1\|WP_000767389.1\|3173277_3173754_+\|kinase-inhibitor	unknown	unknown	gnl\|CDD\|182339
NZ_CP046000.1\|WP_000604034.1\|3184635_3185325_-\|molybdate-ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|181841
NZ_CP046000.1\|WP_000815435.1\|3181605_3182601_-\|6-phosphogluconolactonase	unknown	unknown	gnl\|CDD\|182912
NZ_CP046000.1\|WP_000044825.1\|3168239_3168917_-\|ATP-dependent-dethiobiotin-synthetase-BioD	unknown	unknown	gnl\|CDD\|234625
NZ_CP046000.1\|WP_154139546.1\|3173905_3175189_+\|putative-acyl-CoA-thioester-hydrolase	unknown	unknown	gnl\|CDD\|236709
NZ_CP046000.1\|WP_000101994.1\|3185324_3186098_-\|molybdate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|182641
NZ_CP046000.1\|WP_001036475.1\|3177866_3179300_-\|anion-permease	unknown	unknown	gnl\|CDD\|279307
NZ_CP046000.1\|WP_000723652.1\|3179375_3180428_-\|4-oxalomesaconate-tautomerase	unknown	unknown	gnl\|CDD\|380230
NZ_CP046000.1\|WP_000246805.1\|3168909_3169665_-\|malonyl-ACP-O-methyltransferase-BioC	unknown	unknown	gnl\|CDD\|182340
NZ_CP046000.1\|WP_001389241.1\|3171929_3173219_+\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	unknown	unknown	gnl\|CDD\|181189

Protein	Function_ID	Function_description	E-value
NZ_CP046000.1\|WP_000042533.1\|3165639_3167661_-\|excinuclease-ABC-subunit-B	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
NZ_CP046000.1\|WP_001295301.1\|3163153_3164143_-\|GTP-3',8-cyclase-MoaA	gnl\|CDD\|234672	PRK00164, moaA, GTP 3',8-cyclase MoaA.	0
NZ_CP046000.1\|WP_000951213.1\|3170802_3171843_-\|biotin-synthase-BioB	gnl\|CDD\|185063	PRK15108, PRK15108, biotin synthase; Provisional.	0
NZ_CP046000.1\|WP_000679972.1\|3180611_3181565_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176131	cd08440, PBP2_LTTR_like_4, TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.09679e-82
NZ_CP046000.1\|WP_001295302.1\|3164539_3165448_+\|uridine-diphosphate-N-acetylglucosamine-binding-protein-YvcK	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	2.22556e-139
NZ_CP046000.1\|WP_000593936.1\|3175422_3177684_-\|hydratase	gnl\|CDD\|183125	PRK11413, PRK11413, putative hydratase; Provisional.	0
NZ_CP046000.1\|WP_000891685.1\|3183574_3184633_-\|molybdenum-ABC-transporter-ATP-binding-protein-ModC	gnl\|CDD\|182993	PRK11144, modC, molybdenum ABC transporter ATP-binding protein ModC.	0
NZ_CP046000.1\|WP_001471254.1\|3169651_3170806_-\|8-amino-7-oxononanoate-synthase	gnl\|CDD\|235655	PRK05958, PRK05958, 8-amino-7-oxononanoate synthase; Reviewed.	0
NZ_CP046000.1\|WP_000891515.1\|3186264_3186414_-\|multidrug-efflux-pump-associated-protein,-AcrZ-family	gnl\|CDD\|371231	pfam10766, AcrZ, Multidrug efflux pump-associated protein AcrZ. AcrZ is associated with the AcrA-TolC multidrug efflux pump, it may enhance the ability of the pump to recognize and export certain substrates.	1.04381e-17
NZ_CP046000.1\|WP_000213425.1\|3182755_3183574_+\|pyridoxal-phosphatase	gnl\|CDD\|182523	PRK10530, PRK10530, pyridoxal phosphate (PLP) phosphatase; Provisional.	0
NZ_CP046000.1\|WP_000767389.1\|3173277_3173754_+\|kinase-inhibitor	gnl\|CDD\|182339	PRK10257, PRK10257, putative kinase inhibitor protein; Provisional.	1.08182e-118
NZ_CP046000.1\|WP_000604034.1\|3184635_3185325_-\|molybdate-ABC-transporter-permease-subunit	gnl\|CDD\|181841	PRK09421, modB, molybdate ABC transporter permease subunit.	2.41762e-146
NZ_CP046000.1\|WP_000815435.1\|3181605_3182601_-\|6-phosphogluconolactonase	gnl\|CDD\|182912	PRK11028, PRK11028, 6-phosphogluconolactonase; Provisional.	0
NZ_CP046000.1\|WP_000044825.1\|3168239_3168917_-\|ATP-dependent-dethiobiotin-synthetase-BioD	gnl\|CDD\|234625	PRK00090, bioD, ATP-dependent dethiobiotin synthetase BioD.	1.43396e-108
NZ_CP046000.1\|WP_154139546.1\|3173905_3175189_+\|putative-acyl-CoA-thioester-hydrolase	gnl\|CDD\|236709	PRK10531, PRK10531, putative acyl-CoA thioester hydrolase.	0
NZ_CP046000.1\|WP_000101994.1\|3185324_3186098_-\|molybdate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|182641	PRK10677, modA, molybdate transporter periplasmic protein; Provisional.	0
NZ_CP046000.1\|WP_001036475.1\|3177866_3179300_-\|anion-permease	gnl\|CDD\|279307	pfam00939, Na_sulph_symp, Sodium:sulfate symporter transmembrane region. There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.	0
NZ_CP046000.1\|WP_000723652.1\|3179375_3180428_-\|4-oxalomesaconate-tautomerase	gnl\|CDD\|380230	NF033377, OMA_tautomer, 4-oxalomesaconate tautomerase.	0
NZ_CP046000.1\|WP_000246805.1\|3168909_3169665_-\|malonyl-ACP-O-methyltransferase-BioC	gnl\|CDD\|182340	PRK10258, PRK10258, biotin biosynthesis protein BioC; Provisional.	1.57982e-172
NZ_CP046000.1\|WP_001389241.1\|3171929_3173219_+\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	gnl\|CDD\|181189	PRK07986, PRK07986, adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated.	0

>NZ_CP046000.1|WP_154139546.1|3173905_3175189_+|putative-acyl-CoA-thioester-hydrolase
MNTFSVSRLALALAFGVTLTACSSTPPDQRPSDQTAPGTSSRPILSAKEAQNFDAQHYFASLTPGAAAWNPSPITLPVQPDFVVGPAGTQGVTHTTIQAAVDAAIIKRTNKRQYIAVMPGEYQGTVYVPAAPGGITLYGTGEKPIDVKIGLSLDGGMSPADWRHDVNPRGKYMPGKPAWYMYDSCQSKRSDSIGVLCSAVFWSQNNGLQLQNLTIENTLGDSVDAGNHPAVALRTDGDQVQINNVNILGRQNTFFVTNSGVQNRLETNRQPRTLVTNSYIEGDVDIVSGRGAVVFDNTEFRVVNSRTQQEAYVFAPATLSNIYYGFLAVNSRFNAFGDGVAQLGRSLDVDANTNGQVVIRDSAINEGFNTAKPWADAVISNRPFAGNTGSVDDNDEIQRNLNDTNYNRMWEYNNRGVGSKVVAEAKK
>NZ_CP046000.1|WP_000767389.1|3173277_3173754_+|kinase-inhibitor
MKLISNDLRDGDKLPHRHVFNGMGYDGDNISPHLAWDDVPAGTKSFVVTCYDPDAPTGSGWWHWVVVNLPADTRVLPQGFGSGLVAMPDGVLQTRTDFGKTGYDGAAPPKGETHRYIFTVHALDIERIDVDEGASGAMVGFNVHFHSLASASITAMFS
>NZ_CP046000.1|WP_001389241.1|3171929_3173219_+|adenosylmethionine--8-amino-7-oxononanoate-transaminase
MTTDDLAFDQRHIWHPYTSMTSPLPVYPVASAEGCELILSDGRRLVDGMSSWWAAIHGYNHPQLNAAMKSQIDAMSHVMFGGITHTPAIELCRKLVAMTPQPLECVFLADSGSVAVEVAMKMALQYWQAKGEARQRFLTFRNGYHGDTFGAMSVCDPDNSMHSLWKGYLPENLFAPAPQSRMDGEWDERDMVGFARLMAAHRHEIAAVIIEPIVQGAGGMRMYHPEWLKRIRKMCDREGILLIADEIATGFGRTGKLFACEYAEIAPDILCLGKALTGGTMTLSATLTTREVAETISNGEAGCFMHGPTFMGNPLACAAANASLAILESGDWQQQVADIEVQLREQLAPARNAEMVADVRVLGAIGVVETTRPVNMAALQKFFVEQGVWIRPFGKLIYLMPPYIILPQQLQRLTAAVNRAVQDETFFCQ
>NZ_CP046000.1|WP_000951213.1|3170802_3171843_-|biotin-synthase-BioB
MAHRPRWTLSQVTELFEKPLLDLLFEAQQVHRQHFDPRQVQVSTLLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLESARKAKAAGSTRFCMGAAWKNPHERDMPYLEQMVQGVKAMGLEACMTLGTLSESQAQRLANAGLDYYNHNLDTSPEFYGNIITTRTYQERLDTLEKVRDAGIKVCSGGIVGLGETVKDRAGLLLQLANLPTPPESVPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPEEDKDLQLFRKLGLNPQQTAVLAGDNEQQQRLEQALMTPDTDEYYNAAAL
>NZ_CP046000.1|WP_001471254.1|3169651_3170806_-|8-amino-7-oxononanoate-synthase
MSWQEKINAALDARRAADALRRRYPVAQGAGRWLVADDRQYLNFSSNDYLGLSHHPQIIRAWQQGAEQFGVGSGGSGHVSGYSVAHQALEEELAEWLGYSRALLFISGFAANQAVIAAMMAKEDRIVADRLSHASLLEAASLSPSQLRRFAHNDVTHLARLLASPCPGQQLVVTEGVFSMDGDSAPLAEIQQVTQQHNGWLMVDDAHGTGVIGEQGRGSCWLQKVKPELLVVTFGKGFGVSGAAVLCSSTMADYLLQFARHLIYSTSMPPAQAQALRASLAVIRRDEGDARREKLVSLIARFRAGVQDLPFTLADSCSAIQPLIVGDNSRALQLAEKLRQQGCWVTAIRPPTVPAGTARLRLTLTAAHEMQDIDRLLEVLHGNG
>NZ_CP046000.1|WP_000246805.1|3168909_3169665_-|malonyl-ACP-O-methyltransferase-BioC
MATVNKQAIAAAFGRAAALYEQHADLQRQSADVLLAMLPQRKYTHVLDAGCGPGWMSRHWRERHAQVTALDLSPPMLVQARQKDAADHYLAGDIESLPLATATFDLAWSNLAVQWCGNLSTALRELYRVVRPGGVVAFTTLVQGSLPELHQAWQAVDERPHANRFLPPDEIEQSLNGVHYQHHIQPITLWFDDALSAMRSLKGIGATHLHEGRDPRILTRSQLQRLQLAWPQQQGRYPLTYHLFLGVIARE
>NZ_CP046000.1|WP_000044825.1|3168239_3168917_-|ATP-dependent-dethiobiotin-synthetase-BioD
MSKRYFVTATDTEVGKTVASCALLQAAKAVGYRTAGYKPVASGSEKTPEGLRNSDALALQHNSSLQLDYATVNPYTFAEPTSPHIISAQEGRPIESLVMSAGLRALEQQADWVLVEGAGGWFTPLSDTFTFADWVTQEQLPVILVVGVKLGCINHAMLTAQAIQHAGLTLAGWVANDVTPPGKRHAEYMTTLTRMIPAPLLGEIPWLAENPENAATGKYINLALL
>NZ_CP046000.1|WP_000042533.1|3165639_3167661_-|excinuclease-ABC-subunit-B
MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLHLTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPRFTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGEPPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYELEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELEGLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS
>NZ_CP046000.1|WP_001295302.1|3164539_3165448_+|uridine-diphosphate-N-acetylglucosamine-binding-protein-YvcK
MRNRTLADLDRVVALGGGHGLGRVLSSLSSLGSRLTGIVTTTDNGGSTGRIRRSEGGIAWGDMRNCLNQLITEPSVASAMFEYRFGGNGELSGHNLGNLMLKALDHLSVRPLEAINLIRNLLKVDTHLIPMSEHPVDLMAIDDQGHEVYGEVNIDQLTTPIQELLLTPNVPATREAVHAINEADLIIIGPGSFYTSLMPILLLKEIAQALRRTPAPMVYIGNLGRELSLPAANLKLESKLAIMEQYVGKKVIDAVIVGPKVDVSAVKERIVIQEVLEASDIPYRHDRQLLHNALEKALQALG
>NZ_CP046000.1|WP_001295301.1|3163153_3164143_-|GTP-3',8-cyclase-MoaA
MASQLTDAFARKFYYLRLSITDVCNFRCTYCLPDGYKPSGVTNKGFLTVDEIRRVTRAFASLGTEKVRLTGGEPSLRRDFTDIIAAVRENDAIRQIAVTTNGYRLERDVANWRDAGLTGINVSVDSLDARQFHAITGQDKFNQVMAGIDAAFEAGFEKVKVNTVLMRDVNHHQLDTFLNWIQHRPIQLRFIELMETGEGSELFRKHHISGQVLRDELLRRGWIHQLRQRSDGPAQVFCHPDYAGEIGLIMPYEKDFCATCNRLRVSSIGKLHLCLFGEGGVNLRDLLEDDTQQQALEARISAALREKKQTHFLHQNNTGITQNLSYIGG
>NZ_CP046000.1|WP_000593936.1|3175422_3177684_-|hydratase
MIKLSEKGVFLASNNEIIAEEHFTGEIKKEEAKKGTIAWSILSSHNTSGNMDKLKIKFDSLASHDITFVGIVQTAKASGMERFPLPYVLTNCHNSLCAVGGTINGDDHVFGLSAAQRYGGIFVPPHIAVIHQYMREMMAGGGKMILGSDSHTRYGALGTMAVGEGGGELVKQLLNDTWDIDYPGVVAVHLTGKPAPYVGPQDVALAIIGAVFKNGYVKNKVMEFVGPGVSALSTDFRNSVDVMTTETTCLSSVWQTDEEVHNWLALHGRGQDYCQLNPQPMAYYDGCISVDLSAIKPMIALPFHPSNVYEIDTLNQNLTDILREIEIESERVAHGKAKLSLLDKVENGRLKVQQGIIAGCSGGNYENVIAAANALRGQSCGNDTFSLAVYPSSQPVFMDLAKKGVVADLIGAGAIIRTAFCGPCFGAGDTPINNGLSIRHTTRNFPNREGSKPANGQMSAVALMDARSIAATAANGGYLTSASELDCWDNVPEYAFDVTPYKNRVYQGFVKGATQQPLIYGPNIKDWPELGALTDNIVLKVCSKILDEVTTTDELIPSGETSSYRSNPIGLAEFTLSRRDPGYVGRSKATAELENQRLAGNVSELTEVFARIKQIAGQEHIDPLQTEIGSMVYAVKPGDGSAREQAASCQRVIGGLANIAEEYATKRYRSNVINWGMLPLQMAEVPTFEVGDYIYIPGIKAALDNPGTTFKGYVIHEDAPVTEITLYMESLTAEEREIIKAGSLINFNKNRQM
>NZ_CP046000.1|WP_001036475.1|3177866_3179300_-|anion-permease
MNKKSLWKLILILAIPCIIGFMPAPAGLSELAWVLFGIYLAAIVGLVIKPFPEPVVLLIAVAASMVVVGNLSDGAFKTTAVLSGYSSGTTWLVFSAFTLSAAFVTTGLGKRIAYLLIGKIGNTTLGLGYVTVFLDLVLAPATPSNTARAGGIVLPIINSVAVALGSEPEKSPRRVGHYLMMSIYMVTKTTSYMFFTAMAGNILALKMINDILHLQISWGGWALAAGLPGIIMLLVTPLVIYTMYPPEIKKVDNKTIAKAGLAELGPMKIREKMLLGVFVLALLGWIFSKSLGVDESTVAIVVMATMLLLGIVTWEDVVKNKGGWNTLIWYGGIIGLSSLLSKVKFFEWLAEVFKNNLAFDGHGNVAFFVIIFLSIIVRYFFASGSAYIVAMLPVFAMLANVSGAPLMLTALALLFSNSYGGMVTHYGGAAGPVIFGVGYNDIKSWWLVGAVLTILTFLVHITLGVWWWNMLIGWNML
>NZ_CP046000.1|WP_000723652.1|3179375_3180428_-|4-oxalomesaconate-tautomerase
MKKIPCVMMRGGTSRGAFLLAEHLPEDQTQRDKILMAIMGSGNDLEIDGIGGGNPLTSKVAIISRSSDPRADVDYLFAQVIVHEQRVDTTPNCGNMLSGVGAFAIENGLIAATSPVTRVRIRNVNTGTFIEADVQTPNGVVEYEGSARIDGVPGTAAPVALTFLNAAGTKTGKVFPTDNQIDYFDDVPVTCIDMAMPVVIIPAEYLGKTGYELPAELDADKALLARIESIRLQAGKAMGLGDVSNMVIPKPVLISPAQKGGAINVRYFMPHSCHRALAITGAIAISSSCALEGTVTRQIVPSVGYGNINIEHPSGALDVHLSNEGQDATTLRASVIRTTRKIFSGEVYLP
>NZ_CP046000.1|WP_000679972.1|3180611_3181565_+|LysR-family-transcriptional-regulator
MKHELSSMKAFVILAESSSFNNAAKLLNITQPALTRRIKKMEEDLHIQLFERTTRKVTLTKAGKRLLPEARELIKKFDETLFNIRDMNAYHRGMVTLACIPTAVFYFLPLAIGKFNELYPNIKVRILEQGTNNCMESVLCNESDFGINMNNVTNSSIDFTPLVNEPFVLACRRDHPLAKKQLVEWQELVGYKMIGVRSSSGNRLLIEQQLADKPWKLDWFYEVRHLSTSLGLVEAGLGISALPGLAMPHAPYSSIIGIPLVEPVIRRTLGIIRRKDAVLSPAAERFFALLINLWTDDKDNLWTNIVERQRHALQEIG
>NZ_CP046000.1|WP_000815435.1|3181605_3182601_-|6-phosphogluconolactonase
MKQTVYIASPESQQIHVWNLNHEGALTLTQVVDVPGQVQPMVVSPDKRYLYVGVRPEFRVLAYRIAPDDGALTFAAESALPGSPTHISTDHQGQFVFVGSYNAGNVSVTRLEDGLPVGVVDVVEGLDGCHSANISPDNRTLWVPALKQDRICLFTVSDDGHLVAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTLDMMPENFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSKEGFQPTETQPRGFNVDHSGKYLIAAGQKSHHISVYEIVGEQGLLHEKGRYAVGQGPMWVVVNAH
>NZ_CP046000.1|WP_000213425.1|3182755_3183574_+|pyridoxal-phosphatase
MTTRVIALDLDGTLLTPKKTLLPSSIEALARAREAGYQLIIVTGRHHVAIHPFYQALALDTPAICCNGTYLYDYHAKTVLEADPMPVNKALQLIEMLNEHHIHGLMYVDDAMVYEHPTGHVIRTSNWAQTLPPEQRPTFTQVASLAETAQQVNAVWKFALTHDDLPQLQHFGKHVEHELGLECEWSWHDQVDIARGGNSKGKRLTKWVEAQGWSMENVVAFGDNFNDISMLEAAGTGVAMGNADDAVKARANIVIGDNTTDSIAQFIYSHLI
>NZ_CP046000.1|WP_000891685.1|3183574_3184633_-|molybdenum-ABC-transporter-ATP-binding-protein-ModC
MLELNFSQTLGNHCLTINETLPANGITAIFGVSGAGKTSLINAISGLTRPQKGRIVLNGRVLNDAEKGICLTPEKRRVGYVFQDARLFPHYKVRGNLRYGMAKSMVDQFDKLVALLGIEPLLDRLPGSLSGGEKQRVAIGRALLTAPELLLLDEPLASLDIPRKRELLPYLQRLTREINIPMLYVSHSLDEILHLADRVMVLENGQVKAFGALEEVWGSSVMNPWLPKEQQSSILKVTVLEHHPHYAMTALALGDQHLWVNKLDEPLQAALRIRIQASDVSLVLQPPQQTSIRNVLRAKVVNSYDDNGQVEVELEVGGKTLWARISPWARDELVIKPGLWLYAQIKSVSITA
>NZ_CP046000.1|WP_000604034.1|3184635_3185325_-|molybdate-ABC-transporter-permease-subunit
MILTDPEWQAVLLSLKVSSLAVLFSLPFGIFFAWLLVRCTFPGKALLDSVLHLPLVLPPVVVGYLLLVSMGRRGFIGERLYDWFGITFAFSWRGAVLAAAVMSFPLMVRAIRLALEGVDVKLEQAARTLGAGRWRVFFTITLPLTLPGIIVGTVLAFARSLGEFGATITFVSNIPGETRTIPSAMYTLIQTPGGESGAARLCIISIALAMISLLISEWLARISRERAGR
>NZ_CP046000.1|WP_000101994.1|3185324_3186098_-|molybdate-ABC-transporter-substrate-binding-protein
MARKWLNLFAGAALSFAVAGNALADEGKITVFAAASLTNAMQDIATQYKKEKGVDVVSSFASSSTLARQIEAGAPADLFISADQKWMDYAVDKKAIDTATRQTLLGNSLVVVAPKASEQKDFTIDSKTNWTSLLNGGRLAVGDPEHVPAGIYAKEALQKLGAWDTLSPKLAPAEDVRGALALVERNEAPLGIVYGSDAVASKGVKVVATFPEDSHKKVEYPVAVVEGHNNATVKAFYDYLKGPQAAEIFKRYGFTTK
>NZ_CP046000.1|WP_000891515.1|3186264_3186414_-|multidrug-efflux-pump-associated-protein,-AcrZ-family
MLELLKSLVFAVIMVPVVMAIILGLIYGLGEVFNIFSGVGKKDQPGQNH

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Crispr_ID: NZ_CP046000_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP046000_6

3417387-3417483

Orphan

Consensus_repeat	Method
TTGTAGGCCTGATAAGATGCGTCAAGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP046000_6

>merge|NZ_CP046000|6|3417387-3417483|CRISPRCasFinder
TTGTAGGCCTGATAAGATGCGTCAAGCATCGCATCAGGCATTGTGCACCAATTGCCGGATGCGGCACCGGTTGTAGGCCTGATAAGACGCGTCAAGC

>NZ_CP046000|6|6|3417387-3417483|CRISPRCasFinder
TTGTAGGCCTGATAAGATGCGTCAAGC	ATCGCATCAGGCATTGTGCACCAATTGCCGGATGCGGCACCGG
TTGTAGGCCTGATAAGACGCGTCAAGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046000.1\|WP_000212252.1\|3414908_3415631_+\|UDP-2,3-diacylglucosamine-diphosphatase	unknown	unknown	gnl\|CDD\|235420
NZ_CP046000.1\|WP_000580836.1\|3420501_3422169_-\|acyl-CoA-synthetase-FdrA	unknown	unknown	gnl\|CDD\|180395
NZ_CP046000.1\|WP_000006887.1\|3428241_3429603_-\|allantoinase-AllB	unknown	unknown	gnl\|CDD\|169193
NZ_CP046000.1\|WP_000776555.1\|3410084_3410627_-\|type-1-fimbrial-protein-subunit-FimA	unknown	unknown	gnl\|CDD\|237920
NZ_CP046000.1\|WP_001298987.1\|3426883_3428185_-\|uracil/xanthine-transporter	unknown	unknown	gnl\|CDD\|183124
NZ_CP046000.1\|WP_000540996.1\|3424802_3425588_+\|(S)-ureidoglycine-aminohydrolase	unknown	unknown	gnl\|CDD\|200251
NZ_CP046000.1\|WP_001297443.1\|3423556_3424792_+\|allantoate-deiminase	unknown	unknown	gnl\|CDD\|274471
NZ_CP046000.1\|WP_000855388.1\|3417516_3418410_-\|carbamate-kinase	unknown	unknown	gnl\|CDD\|181831
NZ_CP046000.1\|WP_001143552.1\|3412295_3412817_+\|metal-dependent-hydrolase	unknown	unknown	gnl\|CDD\|224899
NZ_CP046000.1\|WP_000703911.1\|3422485_3423535_+\|ureidoglycolate-dehydrogenase	unknown	unknown	gnl\|CDD\|184985
NZ_CP046000.1\|WP_000815522.1\|3416254_3417322_+\|5-(carboxyamino)imidazole-ribonucleotide-synthase	unknown	unknown	gnl\|CDD\|235674
NZ_CP046000.1\|WP_000495365.1\|3419232_3420492_-\|DUF1116-domain-containing-protein	unknown	unknown	gnl\|CDD\|377673
NZ_CP046000.1\|WP_000190288.1\|3411975_3412188_+\|ribosome-associated-protein-YbcJ	unknown	unknown	gnl\|CDD\|183166
NZ_CP046000.1\|WP_001301143.1\|3418406_3419222_-\|DUF2877-domain-containing-protein	unknown	unknown	gnl\|CDD\|378658
NZ_CP046000.1\|WP_001295318.1\|3415748_3416258_+\|5-(carboxyamino)imidazole-ribonucleotide-mutase	unknown	unknown	gnl\|CDD\|223119
NZ_CP046000.1\|WP_000988378.1\|3409172_3409865_-\|type-1-fimbria-chaperone-FimC	unknown	unknown	gnl\|CDD\|185117
NZ_CP046000.1\|WP_000729154.1\|3411107_3411974_+\|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase-FolD	unknown	unknown	gnl\|CDD\|236760
NZ_CP046000.1\|WP_000912345.1\|3412852_3414238_-\|cysteine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234705
NZ_CP046000.1\|WP_001315307.1\|3425716_3426862_-\|glycerate-3-kinase	unknown	unknown	gnl\|CDD\|182152
NZ_CP046000.1\|WP_000256002.1\|3414411_3414906_+\|peptidylprolyl-isomerase-B	unknown	unknown	gnl\|CDD\|182734

Protein	Function_ID	Function_description	E-value
NZ_CP046000.1\|WP_000212252.1\|3414908_3415631_+\|UDP-2,3-diacylglucosamine-diphosphatase	gnl\|CDD\|235420	PRK05340, PRK05340, UDP-2,3-diacylglucosamine hydrolase; Provisional.	1.37025e-165
NZ_CP046000.1\|WP_000580836.1\|3420501_3422169_-\|acyl-CoA-synthetase-FdrA	gnl\|CDD\|180395	PRK06091, PRK06091, membrane protein FdrA; Validated.	0
NZ_CP046000.1\|WP_000006887.1\|3428241_3429603_-\|allantoinase-AllB	gnl\|CDD\|169193	PRK08044, PRK08044, allantoinase AllB.	0
NZ_CP046000.1\|WP_000776555.1\|3410084_3410627_-\|type-1-fimbrial-protein-subunit-FimA	gnl\|CDD\|237920	PRK15194, PRK15194, type 1 fimbrial protein subunit FimA.	9.67411e-92
NZ_CP046000.1\|WP_001298987.1\|3426883_3428185_-\|uracil/xanthine-transporter	gnl\|CDD\|183124	PRK11412, PRK11412, uracil/xanthine transporter.	0
NZ_CP046000.1\|WP_000540996.1\|3424802_3425588_+\|(S)-ureidoglycine-aminohydrolase	gnl\|CDD\|200251	TIGR03214, ura-cupin, putative allantoin catabolism protein. This model represents a protein containing a tandem arrangement of cupin domains (N-terminal part of pfam07883 and C-terminal more distantly related to pfam00190). This protein is found in the vicinity of genes involved in the catabolism of allantoin, a breakdown product of urate and sometimes of urate iteslf. The distribution of pathway components in the genomes in which this family is observed suggests that the function is linked to the allantoate catabolism to glyoxylate pathway (GenProp0686) since it is sometimes found in genomes lacking any elements of the xanthine-to-allantoin pathways (e.g. in Enterococcus faecalis).	4.3298e-152
NZ_CP046000.1\|WP_001297443.1\|3423556_3424792_+\|allantoate-deiminase	gnl\|CDD\|274471	TIGR03176, AllC, allantoate amidohydrolase. This enzyme catalyzes the breakdown of allantoate, first to ureidoglycine by hydrolysis and then decarboxylation of one of the two equivalent ureido groups. Ureidoglycine then spontaneously exchanges ammonia for water resulting in ureidoglycolate. This enzyme is an alternative to allantoicase (3.5.3.4) which releases urea. [Central intermediary metabolism, Nitrogen metabolism].	0
NZ_CP046000.1\|WP_000855388.1\|3417516_3418410_-\|carbamate-kinase	gnl\|CDD\|181831	PRK09411, PRK09411, carbamate kinase; Reviewed.	0
NZ_CP046000.1\|WP_001143552.1\|3412295_3412817_+\|metal-dependent-hydrolase	gnl\|CDD\|224899	COG1988, COG1988, Predicted membrane-bound metal-dependent hydrolases [General function prediction only].	1.06651e-30
NZ_CP046000.1\|WP_000703911.1\|3422485_3423535_+\|ureidoglycolate-dehydrogenase	gnl\|CDD\|184985	PRK15025, PRK15025, ureidoglycolate dehydrogenase; Provisional.	0
NZ_CP046000.1\|WP_000815522.1\|3416254_3417322_+\|5-(carboxyamino)imidazole-ribonucleotide-synthase	gnl\|CDD\|235674	PRK06019, PRK06019, phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed.	1.21739e-179
NZ_CP046000.1\|WP_000495365.1\|3419232_3420492_-\|DUF1116-domain-containing-protein	gnl\|CDD\|377673	pfam06545, DUF1116, Protein of unknown function (DUF1116). This family contains hypothetical bacterial proteins of unknown function.	1.8369e-131
NZ_CP046000.1\|WP_000190288.1\|3411975_3412188_+\|ribosome-associated-protein-YbcJ	gnl\|CDD\|183166	PRK11507, PRK11507, ribosome-associated protein YbcJ.	1.38756e-42
NZ_CP046000.1\|WP_001301143.1\|3418406_3419222_-\|DUF2877-domain-containing-protein	gnl\|CDD\|378658	pfam11392, DUF2877, Protein of unknown function (DUF2877). This bacterial family of proteins are putative carboxylase proteins however this cannot be confirmed.	4.08791e-37
NZ_CP046000.1\|WP_001295318.1\|3415748_3416258_+\|5-(carboxyamino)imidazole-ribonucleotide-mutase	gnl\|CDD\|223119	COG0041, PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism].	1.14024e-91
NZ_CP046000.1\|WP_000988378.1\|3409172_3409865_-\|type-1-fimbria-chaperone-FimC	gnl\|CDD\|185117	PRK15195, PRK15195, molecular chaperone FimC.	1.85595e-148
NZ_CP046000.1\|WP_000729154.1\|3411107_3411974_+\|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase-FolD	gnl\|CDD\|236760	PRK10792, PRK10792, bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD.	0
NZ_CP046000.1\|WP_000912345.1\|3412852_3414238_-\|cysteine--tRNA-ligase	gnl\|CDD\|234705	PRK00260, cysS, cysteinyl-tRNA synthetase; Validated.	0
NZ_CP046000.1\|WP_001315307.1\|3425716_3426862_-\|glycerate-3-kinase	gnl\|CDD\|182152	PRK09932, PRK09932, glycerate 3-kinase.	0
NZ_CP046000.1\|WP_000256002.1\|3414411_3414906_+\|peptidylprolyl-isomerase-B	gnl\|CDD\|182734	PRK10791, PRK10791, peptidylprolyl isomerase B.	2.40187e-121

>NZ_CP046000.1|WP_000815522.1|3416254_3417322_+|5-(carboxyamino)imidazole-ribonucleotide-synthase
MKQVCVLGNGQLGRMLRQAGEPLGIAVWPVGLDAEPAAVPFQQSVITAEIERWPETALTRELARHPAFVNRDVFPIIADRLTQKQLFDKLHLPTAPWQLLADRSEWPAVFDRLGELAIVKRRTGGYDGRGQWRLRADETEQLPAECYGECIVEQGINFSGEVSLVGARGFDGSTVFYPLTHNLHQDGILRTSVAFPQANAQQQAQAEEMLSAIMQELGYVGVMAMECFVTPQGLLINELAPRVHNSGHWTQNGASISQFELHLRAITDLPLPQPVVNNPSVMINLIGSDANYDWLKLPLVHLHWYDKEVRPGRKVGHLNLTDSDTSRLTATLEALIPLLPPEYASGVIWAQSKFG
>NZ_CP046000.1|WP_001295318.1|3415748_3416258_+|5-(carboxyamino)imidazole-ribonucleotide-mutase
MSSRNNPARVAIVMGSKSDWATMQFAAEIFEILNVPHHVEVVSAHRTPDKLFSFAESAEENGYQVIIAGAGGAAHLPGMIAAKTLVPVLGVPVQSAALSGVDSLYSIVQMPRGIPVGTLAIGKAGAANAALLAAQILATHDKELHQRLNDWRKAQTDEVLENPDPRGAA
>NZ_CP046000.1|WP_000212252.1|3414908_3415631_+|UDP-2,3-diacylglucosamine-diphosphatase
MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQMLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF
>NZ_CP046000.1|WP_000256002.1|3414411_3414906_+|peptidylprolyl-isomerase-B
MVTFHTNHGDIVIKTFDDKAPETVKNFLDYCREGFYNNTIFHRVINGFMIQGGGFEPGMKQKATKEPIKNEANNGLKNTRGTLAMARTQAPHSATAQFFINVVDNDFLNFSGESLQGWGYCVFAEVVEGMDVVDKIKGVATGRSGMHQDVPKEDVIIESVTVSE
>NZ_CP046000.1|WP_000912345.1|3412852_3414238_-|cysteine--tRNA-ligase
MLKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTFVAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRANENGESFVALVDRMIAEMHKDFDALNILRPDMEPRATHHIAEIIELTEQLIAKGHAYVADNGDVMFDVPTDPTYGVLSRQDLDQLQAGARVDVVDDKRNPMDFVLWKMSKEGEPSWPSPWGAGRPGWHIECSAMNCKQLGNHFDIHGGGSDLMFPHHENEIAQSTCAHDGQYVNYWMHSGMVMVDREKMSKSLGNFFTVRDVLKYYDAETVRYFLMSGHYRSQLNYSEENLKQARAALERLYTALRGTDKTVAPAGGEAFEARFIEAMDDDFNTPEAYSVLFDMAREVNRLKAEDMAAANAMASHLRKLSAVLGLLEQEPEAFLQSGAQADDSEVAEIEALIQQRLDARKAKDWAAADAARDRLNEMGIVLEDGPQGTTWRRK
>NZ_CP046000.1|WP_001143552.1|3412295_3412817_+|metal-dependent-hydrolase
MPTVITHAAVPLCIGLGLGSKVIPPRLLFAGIILAMLPDADVLSFKFGVAYGNVFGHRGFTHSLVFAFVVPLLCVLIGRRWFRAGLIRCWLFLTVSLLSHSLLDSVTTGGKGVGWLWPWSDERFFAPWQVIKVAPFALSRYTTPYGHQVIISELMWVWLPGMVLMGMLWWRRR
>NZ_CP046000.1|WP_000190288.1|3411975_3412188_+|ribosome-associated-protein-YbcJ
MATFSLGKHPHVELCDLLKLEGWSESGAQAKIAIAEGQVKVDGAVETRKRCKIVAGQTVSFAGHSVQVVA
>NZ_CP046000.1|WP_000729154.1|3411107_3411974_+|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase-FolD
MAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSNPASQIYVASKRKACEEVGFVSRSYDLPETTSEAELLELIDALNADNTIDGILVQLPLPAGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPGDWIKEGAIVIDVGINRLENGKVVGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTLQACVEYHDPQDE
>NZ_CP046000.1|WP_000776555.1|3410084_3410627_-|type-1-fimbrial-protein-subunit-FimA
MKLRFISSALAAALFAATGSYAAVVDGGTIHFEGELVNAACSVNTDSADQVVTLGQYRTDIFNAVGNTSALIPFTIQLNDCDPVVAANAAVAFSGQADAINDNLLAIASSTNTTTATGVGIEILDNTSAILKPDGNSFSTNQNLIPGTNVLHFSARYKGTGTSASAGQANADATFIMRYE
>NZ_CP046000.1|WP_000988378.1|3409172_3409865_-|type-1-fimbria-chaperone-FimC
MMTKIKLLMLIIFYLIISASSHAAGGIALGATRIIYPADAKQTAVWIRNSHTNERFLVNSWIENSSGVKEKSFIITPPLFVSEPKSENTLRIIYTGPPLAADRESLFWMNVKTIPSVDKNALNGRNVLQLAILSRMKLFLRPIQLQELPAEAPDTLKFSRSGNYINVHNPSPFYVTLVNLQVGSQKLGNAMAAPRVSSQIPLPSGVQGKLKFQTVNDYGSVTPVREVNLN
>NZ_CP046000.1|WP_000855388.1|3417516_3418410_-|carbamate-kinase
MKTLVVALGGNALLQRGEALTAENQYRNIASAVPALARLARSYRLAIVHGNGPQVGLLALQNLAWKEVEPYPLDVLVAESQGMIGYMLAQSLSAQPQMPPVTTVLTRIEVSPDDPAFLQPEKFIGPVYQPEEQEALEAAYGWQMKRDGKYLRRVVASPQPRKILDSEAIELLLKEGHVVICSGGGGVPVTEDGAGSEAVIDKDLAAALLAEQINADGLVILTDADAVYENWGTPQQRAIRHATPDELAPFAKADGSMGPKVTAVSGYVRSRGKPAWIGALSRIEETLAGEAGTCISL
>NZ_CP046000.1|WP_001301143.1|3418406_3419222_-|DUF2877-domain-containing-protein
MTIIHPLLASRSAPNYRQSWRLAGVWRRAINLMTESGELLTLHRQGSGFGPGGWVLRRAQFDALCGGLCGNERPQVVAQGIRLGRFTVKQPQRYCLLRITPPAHPQPLAAAWMQRAEETGLFGPLALAASDPLTAELRQFRHCFQAALNGVKTDWRHWLGKGPGLTPSHDDTLSGMLLAAWYYGALDARSGRPFFACSDNLQLVTTAVSVSYLRYAAQGYFASPLLHFVHALSCPKRTAVAIDSLLALGHTSGADTLLGFWLGQQLLQGKP
>NZ_CP046000.1|WP_000495365.1|3419232_3420492_-|DUF1116-domain-containing-protein
MFTSVAQANAAVIEQIRRARPHWLDVQPASSLISELNEGKTLLHAGPPMRWQEMTGPMKGACVGACLFEGWAKDEAQALAILEQGEVNFIPCHHVNAVGPMGGITSASMPMLVVENVTDGNRAYCNLNEGIGKVMRFGAYGEDVLTRHRWMRDVLMPVLSAALGRMERGIDLTAMMAQGITMGDEFHQRNIASSALLMRALAPQIARLDHDKQHIAEVMDFLSVTDQFFLNLAMAYCKAAMDAGAMIRAGSIVTAMTRNGNMFGIRVSGLGERWFTAPVNTPQGLFFTGFSQEQANPDMGDSAITETFGIGGAAMIAAPGVTRFVGAGGMEAARAVSEEMAEIYLERNMQLQIPGWDFQGACLGLDIRRVVETGITPLINTGIAHKEAGIGQIGAGTVRAPLACFEQALEALAESMGIG
>NZ_CP046000.1|WP_000580836.1|3420501_3422169_-|acyl-CoA-synthetase-FdrA
MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATPNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELTNQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGHLGVEADDTHHHGMMLDADGHQIIDLGDDFYTVGRPHPMIDPALRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARSDSQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSSATQQHTPSLLENVAVINIGLRSFALELQSASKPVVHYQWSPVAGGNKKLARLLERLQ
>NZ_CP046000.1|WP_000703911.1|3422485_3423535_+|ureidoglycolate-dehydrogenase
MKISRETLHQLIENKLCQAGLKREHAATVAEVLVYADARGIHSHGAVRVEYYAERISKGGTNREPEFRLEETGPCSAILHADNAAGQVAAKMGMEHAIKTAQQNGVAVVGISRMGHSGAISYFVQQAARAGLIGISMCQSDPMVVPFGGAEIYYGTNPLAFAAPGEGDEILTFDMATTVQAWGKVLDARSRNMSIPDTWAVDKNGAPTTDPFAVHALLPAAGPKGYGLMMMIDVLSGVLLGLPFGRQVSSMYDDLHAGRNLGQLHIVINPNFFSSSELFRQHLSQTMRELNAITPAPGFNQVYYPGQDQDIKQRKAAVEGIEIVDDIYQYLISDALYNTSYETKNPFAQ
>NZ_CP046000.1|WP_001297443.1|3423556_3424792_+|allantoate-deiminase
MITHFRQAIEETLPWLSSFGADPTGGMTRLLYSPEWLETQQQFKKRMAASGLETRFDEVGNLYGRLNGTEYPQEVILSGSHIDTVVNGGNLDGQFGALAAWLAIDWLKTQYGAPLRTVEVVAMAEEEGSRFPYVFWGSKNIFGLANPDDVRNICDAKGNSFVDAMKACGFTLPNAPLTPRQDIKAFVELHIEQGCVLESNGQSIGVVNAIVGQRRYTVTLNGESNHAGTTPMGYRRDTVYAFSRICHQSVEKAKRMGDPLVLTFGKVEPHPNTVNVVPGKTTFTIDCRHTDAAVLRDFTQQLENDMRAICDEMDIGIDIDLWMDEEPVPMNKELVATLTELCEREKLNYRVMHSGAGHDAQIFAPRVPTCMIFIPSINGISHNPAERTNITDLAEGVKTLALMLYQLAWQK
>NZ_CP046000.1|WP_000540996.1|3424802_3425588_+|(S)-ureidoglycine-aminohydrolase
MGYLNNVTGYREDLLANRAIVKHGNFALLTPDGLVKNIIPGFENCDATILSTPKLGASFVDYLVTLHQNGGNQQGFGGEGIETFLYVISGNITAKAEGKTFALSEGGYLYCPPGSLMTFVNAQAEDSQIFLYKRRYVPVEGHAPWLVSGNASELERIHYEGMDDVILLDFLPKELGFDMNMHILSFAPGASHGYIETHVQEHGAYILSGQGVYNLDNNWIPVKKGDYIFMGAYSLQAGYGVGRGEAFSYIYSKDCNRDVEI
>NZ_CP046000.1|WP_001315307.1|3425716_3426862_-|glycerate-3-kinase
MKIVIAPDSFKESLSAEKCCQAIKAGFSTLFPDANYICLPIADGGEGTVDAMVAATGGNIVTLEVCGPMGETVNAFYGLTGDGKTAVIEMAAASGLMLVAPEKRNPLLASSFGTGELIRHALDNGIRHIILGIGGSATVDGGMGMAQALGVRFLDADGQVLAANGGNLARVASIEMDECDPRLANCHIEVACDVDNPLVGARGAAAVFGPQKGATPEMVEELEQGLQNYARVLQQQTEINVCQMAGGGAAGGMGIAAAVFLNADIKPGIEIVLRAVNLEQAVQGAALVITGEGRIDSQTAGGKAPLGVASVAKQFNVPVIGIAGVLGDGVEVVHQYGIDAVFSILPRLAPLAEVLASGETNLFNSARNIACAIKIGQGIKN
>NZ_CP046000.1|WP_001298987.1|3426883_3428185_-|uracil/xanthine-transporter
MFNFAVSRESLLSGFQWFFFIFCNTVVVPPTLLSAFQLPQSSLLTLTQYAFLATALACFAQAFCGHRRAIMEGPGGLWWGTILTITLGEASRGTPINDIATSLAVGIALSGVLTMLIGFSGLGHRLARLFTPSVMVLFMLMLGAQLTTIFFKGMLGLPFGIADPNFKIQLPPFALSVAVMCLVLGMIIFLPQRFARYGLLVGTITGWLLWYFCFPSSHSLSGELHWQWFPLGSGGALSPGIILTAVITGLVNISNTYGAIRGTDVFYPQQGAGNTRYRRSFVATGFMTLITVPLAVIPFSPFVSSIGLLTQTGDYTRRSFIYGSVICLLVALVPALTRLFCSIPLPVSSAVMLVSYLPLLFSALVFSQQITFTARNIYRLALPLFVGIFLMALPPVYLQDLPLTLRPLLSNGLLVGILLAVLMDNLIPWERIE
>NZ_CP046000.1|WP_000006887.1|3428241_3429603_-|allantoinase-AllB
MSFDLIIKNGTVILENEARVVDIAVKGGKIAAIGQDLGDAKEVMDASGLVVSPGMVDAHTHISEPGRSHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDRASIELKFDAAKGKLTIDAAQLGGLVSYNIDRLHELDEVGVVGFKCFVATCGDRGIDNDFRDVNDWQFFKGAQKLGELGQPVLVHCENALICDALGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLAKVAGCRLHVCHISSPEGVEEVTRARQEGQDVTCESCPHYFVLDTDQFEEIGTLAKCSPPIRDLENQKGMWEKLFNGEIDCLVSDHSPCPPEMKAGNIMEAWGGIAGLQNCMDVMFDEAVQKRGMSLPMFGKLMATNAADIFGLQQKGRIAPGKDADFVFIQPNSSYVLTNDDLEYRHKVSPYVGRTIGARITKTILRGDVIYDIEQGFPVAPKGQFILKHQQ

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Crispr_ID: NZ_CP046000_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP046000_7

3940641-3940756

Orphan

Consensus_repeat	Method
AACGCCTGATGCGACGCTGACGCGTCTTATC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP046000_7

>merge|NZ_CP046000|7|3940641-3940756|CRISPRCasFinder
AACGCCTGATGCGACGCTGACGCGTCTTATCTGGCCTACGCGCTGTGTTTTTGTAGGCCGGATAAGCAAAGCGCATCCGGCATTCAACGCCTGATGCGACGCTGGCGCGTCTTATC

>NZ_CP046000|7|7|3940641-3940756|CRISPRCasFinder
AACGCCTGATGCGACGCTGACGCGTCTTATC	TGGCCTACGCGCTGTGTTTTTGTAGGCCGGATAAGCAAAGCGCATCCGGCATTC
AACGCCTGATGCGACGCTGGCGCGTCTTATC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046000.1\|WP_000525176.1\|3947024_3947684_+\|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA	unknown	unknown	gnl\|CDD\|236659
NZ_CP046000.1\|WP_001148402.1\|3935340_3936105_-\|DedA-family-protein	unknown	unknown	gnl\|CDD\|223659
NZ_CP046000.1\|WP_001200573.1\|3947800_3948616_-\|co-chaperone-DjlA	unknown	unknown	gnl\|CDD\|236512
NZ_CP046000.1\|WP_001248770.1\|3929936_3930068_-\|glucose-uptake-inhibitor-SgrT	unknown	unknown	gnl\|CDD\|374203
NZ_CP046000.1\|WP_000916310.1\|3934528_3935227_+\|thiamine-ABC-transporter-ATP-binding-protein-ThiQ	unknown	unknown	gnl\|CDD\|182716
NZ_CP046000.1\|WP_000888642.1\|3940820_3941516_+\|L-ribulose-5-phosphate-4-epimerase	unknown	unknown	gnl\|CDD\|236181
NZ_CP046000.1\|WP_000610901.1\|3954373_3954751_+\|Co2+/Mg2+-efflux-protein-ApaG	unknown	unknown	gnl\|CDD\|180098
NZ_CP046000.1\|WP_001300811.1\|3936190_3937069_-\|arabinose-operon-transcriptional-regulator-AraC	unknown	unknown	gnl\|CDD\|236717
NZ_CP046000.1\|WP_000151734.1\|3939118_3940621_+\|L-arabinose-isomerase	unknown	unknown	gnl\|CDD\|179503
NZ_CP046000.1\|WP_000241271.1\|3952563_3953553_+\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	unknown	unknown	gnl\|CDD\|234696
NZ_CP046000.1\|WP_154139577.1\|3931975_3932959_+\|thiamine-ABC-transporter-substrate-binding-subunit	unknown	unknown	gnl\|CDD\|236883
NZ_CP046000.1\|WP_000746150.1\|3948870_3951225_+\|LPS-assembly-protein-LptD	unknown	unknown	gnl\|CDD\|235158
NZ_CP046000.1\|WP_000800453.1\|3951277_3952564_+\|peptidylprolyl-isomerase-SurA	unknown	unknown	gnl\|CDD\|236758
NZ_CP046000.1\|WP_025653143.1\|3953549_3954371_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	unknown	unknown	gnl\|CDD\|234708
NZ_CP046000.1\|WP_001389162.1\|3930156_3931812_+\|HTH-type-transcriptional-regulator-SgrR	unknown	unknown	gnl\|CDD\|184188
NZ_CP046000.1\|WP_001117011.1\|3944106_3947013_+\|RNA-polymerase-associated-protein-RapA	unknown	unknown	gnl\|CDD\|235319
NZ_CP046000.1\|WP_000637846.1\|3928656_3929835_-\|sugar-efflux-transporter-SetA	unknown	unknown	gnl\|CDD\|129977
NZ_CP046000.1\|WP_000951798.1\|3937407_3939108_+\|ribulokinase	unknown	unknown	gnl\|CDD\|235221
NZ_CP046000.1\|WP_000235691.1\|3932934_3934545_+\|thiamine/thiamine-pyrophosphate-ABC-transporter-permease-ThiP	unknown	unknown	gnl\|CDD\|181853
NZ_CP046000.1\|WP_000035639.1\|3941590_3943942_+\|DNA-polymerase-II	unknown	unknown	gnl\|CDD\|235595

Protein	Function_ID	Function_description	E-value
NZ_CP046000.1\|WP_000525176.1\|3947024_3947684_+\|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA	gnl\|CDD\|236659	PRK10158, PRK10158, bifunctional tRNA pseudouridine(32) synthase/23S rRNA pseudouridine(746) synthase RluA.	1.37214e-159
NZ_CP046000.1\|WP_001148402.1\|3935340_3936105_-\|DedA-family-protein	gnl\|CDD\|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	2.3759e-49
NZ_CP046000.1\|WP_001200573.1\|3947800_3948616_-\|co-chaperone-DjlA	gnl\|CDD\|236512	PRK09430, djlA, co-chaperone DjlA.	1.09407e-169
NZ_CP046000.1\|WP_001248770.1\|3929936_3930068_-\|glucose-uptake-inhibitor-SgrT	gnl\|CDD\|374203	pfam15894, SgrT, Inhibitor of glucose uptake transporter SgrT.	0.00206924
NZ_CP046000.1\|WP_000916310.1\|3934528_3935227_+\|thiamine-ABC-transporter-ATP-binding-protein-ThiQ	gnl\|CDD\|182716	PRK10771, thiQ, thiamine ABC transporter ATP-binding protein ThiQ.	1.55198e-163
NZ_CP046000.1\|WP_000888642.1\|3940820_3941516_+\|L-ribulose-5-phosphate-4-epimerase	gnl\|CDD\|236181	PRK08193, araD, L-ribulose-5-phosphate 4-epimerase AraD.	1.31794e-177
NZ_CP046000.1\|WP_000610901.1\|3954373_3954751_+\|Co2+/Mg2+-efflux-protein-ApaG	gnl\|CDD\|180098	PRK05461, apaG, CO2+/MG2+ efflux protein ApaG; Reviewed.	3.63315e-76
NZ_CP046000.1\|WP_001300811.1\|3936190_3937069_-\|arabinose-operon-transcriptional-regulator-AraC	gnl\|CDD\|236717	PRK10572, PRK10572, arabinose operon transcriptional regulator AraC.	0
NZ_CP046000.1\|WP_000151734.1\|3939118_3940621_+\|L-arabinose-isomerase	gnl\|CDD\|179503	PRK02929, PRK02929, L-arabinose isomerase; Provisional.	0
NZ_CP046000.1\|WP_000241271.1\|3952563_3953553_+\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	gnl\|CDD\|234696	PRK00232, pdxA, 4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed.	0
NZ_CP046000.1\|WP_154139577.1\|3931975_3932959_+\|thiamine-ABC-transporter-substrate-binding-subunit	gnl\|CDD\|236883	PRK11205, tbpA, thiamine transporter substrate binding subunit; Provisional.	0
NZ_CP046000.1\|WP_000746150.1\|3948870_3951225_+\|LPS-assembly-protein-LptD	gnl\|CDD\|235158	PRK03761, PRK03761, LPS assembly outer membrane complex protein LptD; Provisional.	0
NZ_CP046000.1\|WP_000800453.1\|3951277_3952564_+\|peptidylprolyl-isomerase-SurA	gnl\|CDD\|236758	PRK10770, PRK10770, peptidyl-prolyl cis-trans isomerase SurA; Provisional.	0
NZ_CP046000.1\|WP_025653143.1\|3953549_3954371_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	gnl\|CDD\|234708	PRK00274, ksgA, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA.	1.23367e-147
NZ_CP046000.1\|WP_001389162.1\|3930156_3931812_+\|HTH-type-transcriptional-regulator-SgrR	gnl\|CDD\|184188	PRK13626, PRK13626, HTH-type transcriptional regulator SgrR.	0
NZ_CP046000.1\|WP_001117011.1\|3944106_3947013_+\|RNA-polymerase-associated-protein-RapA	gnl\|CDD\|235319	PRK04914, PRK04914, RNA polymerase-associated protein RapA.	0
NZ_CP046000.1\|WP_000637846.1\|3928656_3929835_-\|sugar-efflux-transporter-SetA	gnl\|CDD\|129977	TIGR00899, Sugar_efflux_transporter_A, sugar efflux transporter. This family of proteins is an efflux system for lactose, glucose, aromatic glucosides and galactosides, cellobiose, maltose, a-methyl glucoside and other sugar compounds. They are found in both gram-negative and gram-postitive bacteria. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	0
NZ_CP046000.1\|WP_000951798.1\|3937407_3939108_+\|ribulokinase	gnl\|CDD\|235221	PRK04123, PRK04123, ribulokinase; Provisional.	0
NZ_CP046000.1\|WP_000235691.1\|3932934_3934545_+\|thiamine/thiamine-pyrophosphate-ABC-transporter-permease-ThiP	gnl\|CDD\|181853	PRK09433, thiP, thiamine transporter membrane protein; Reviewed.	0
NZ_CP046000.1\|WP_000035639.1\|3941590_3943942_+\|DNA-polymerase-II	gnl\|CDD\|235595	PRK05762, PRK05762, DNA polymerase II; Reviewed.	0

>NZ_CP046000.1|WP_000151734.1|3939118_3940621_+|L-arabinose-isomerase
MTIFDNYEVWFVIGSQHLYGPETLRQVTQHAEHVVNALNTEAKLPCKLVLKPLGTTPDEITAICRDANYDDRCAGLVVWLHTFSPAKMWINGLTMLNKPLLQFHTQFNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKQAHERIGSWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVVNSISDGDVNALVDEYESCYTMTPATQIHGEKRQNVLEAARIELGMKRFLEQGGFHAFTTTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMEDYTYHFEKGNDLVLGSHMLEVCPSIAVEEKPILDVQHLGIGGKDDPARLIFNTQTGPAIVASLIDLGDRYRLLVNCIDTVKTPHSLPKLPVANALWKAQPDLPTASEAWILAGGAHHTVFSHALNLNDMRQFAEMHDIEITVIDNDTRLPAFKDALRWNEVYYGFRR
>NZ_CP046000.1|WP_000951798.1|3937407_3939108_+|ribulokinase
MAIAIGLDFGSDSVRALAVDCASGEEIATSVEWYPRWQKGQFCDAPNNQFRHHPRDYIESMEAALKTVLAELSVEQRAAVVGIGVDTTGSTPAPIDANGNVLALRPEFAENPNAMFVLWKDHTAVEEAEEITRLCHAPGNVDYSRYIGGIYSSEWFWAKILHVTRQDSAVAQSAASWIELCDWVPALLSGTTRPQDIRRGRCSAGHKSLWHESWGGLPPASFFDELDPILNRHLPSPLFTDTWTADIPVGTLCPEWAQRLGLPESVVISGGAFDCHMGAVGAGAQPNALVKVIGTSTCDILIADKQSVGERAVKGICGQVDGSVVPGFIGLEAGQSAFGDIYAWFGRVLGWPLEQLAAQHPELKAQINASQKQLLPALTEAWAKNPSLDHLPVVLDWFNGRRTPNANQRLKGVITDLNLATDAPLLFGGLIAATAFGARAIMECFTDQGIAVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAKVHADIPSAQQKMASAVEKTLQPRSEQAQRFEQLYRRYQQWAMSAEQHYLPTSAPAQAAQAVATL
>NZ_CP046000.1|WP_001300811.1|3936190_3937069_-|arabinose-operon-transcriptional-regulator-AraC
MAEAQNDPLLPGYSFNAHLVAGLTPIEANGYLDFFIDRPLGMKGYILNLTIRGQGVVKNQGREFVCRPGDILLFPPGEIHHYGRHPEAREWYHQWVYFRPRAYWHEWLNWPSIFANTGFFRPDEAHQPHFSDLFGQIINAGQGEGRYSELLAINLLEQLLLRRMEAINESLHPPMDNRVREACQYISDHLADSNFDIASVAQHVCLSPSRLSHLFRQQLGISVLSWREDQRISQAKLLLSTTRMPIATVGRNVGFDDQLYFSRVFKKCTGASPSEFRAGCEEKVNDVAVKLS
>NZ_CP046000.1|WP_001148402.1|3935340_3936105_-|DedA-family-protein
MQALLEHFITQSTVYSLMAVVLVAFLESLALVGLILPGTVLMAGLGALIGSGELSFWHAWLAGIVGCLLGDWISFWLGWRFKKPLHRWSFLKKNKALLDKTEHALHQHSMFTILVGRFVGPTRPLVPMVAGMLDLPVAKFITPNIIGCLLWPPFYFLPGILAGAAIDIPAGMQSGEFKWLLLATAVFLWVGGWLCWRLWRSGKATDRLSHYLSRGRLLWLTPLISAIGVVALVVLIRHPLMPVYIDILRKVVGG
>NZ_CP046000.1|WP_000916310.1|3934528_3935227_+|thiamine-ABC-transporter-ATP-binding-protein-ThiQ
MLKLTDITWLYHHLPMRFSLTVERGEQVAILGPSGAGKSTLLNLIAGFLTPASGSLTIDSVDHTTTPPSRRPVSMLFQENNLFSHLTVAQNIGLGLNPGLKLNAAQQEKMHAIARQMGIDNLMARLPGELSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEMLTLVSTSCQQQKMTLLMVSHSVEDAARIATRSVVVADGRIAWQGKTNELLSGKASASALLGITG
>NZ_CP046000.1|WP_000235691.1|3932934_3934545_+|thiamine/thiamine-pyrophosphate-ABC-transporter-permease-ThiP
MATRRQPLIPGWLIPGVSAATLVVAVALAAFLALWWNAPQGNWVAVWQDSYLWHVVRFSFWQAFLSALLSVVPAIFLARALYRRRFPGRLALLRLCAMTLILPVLVAVFGILSVYGHQGWLASLCQSLGLEWTFSPYGLQGILLAHVFFNLPMASRLLLQALENIPGEQRQLAAQLGMRGWHFFRFVEWPWLRRQIPPVAALIFMLCFASFATVLSLGGGPQATTIELAIYQALSYDYDPARAAMLALLQMVCCLGLVLLSQRLSKAIAPGTTLLQGWRDPDDRLHSRICDTVLIVLALLLLLPPLLAVIVDGVNRQLPEVLAQPVLWQALWTSLRIALAAGVLCVVLTMMLLWSSRELRARQKMLAGQALEMSGMLILAMPGIVLATGFFLLLNNTIGLPQSADGIVIFTNALMAIPYALKVLENPMRDITARYSMLCQSLGIEGWSRLKVVELRALKRPLAQALAFACVLSIGDFGVVALFGNDDFRTLPFYLYQQIGSYRSQDGAVTALILLLLCFLLFTVIEKLPGRNVKTD
>NZ_CP046000.1|WP_154139577.1|3931975_3932959_+|thiamine-ABC-transporter-substrate-binding-subunit
MLKKCLPLLLLCTAPVFAKPVLTVYTYDSFAADWGPGPKIKKAFEADCNCELKLVALEDGVSLLNRLRMEGKNSKADVVLGLDNNLLDAASKTGLFAKSGVAADAVNVPGGWNNDTFVPFDYGYFAFVYDKNKLKNPPQSLKELVESDQNWRVIYQDPRTSTPGLGLLLLMQKVYGDDTPQAWQKLAKKTVTVTKGWSEAYGLFLKGESDLVLSYTTSPAYHILEEKKDNYAAANFSEGHYLQVEVAARTAASKQPELAQKFLQFMVSPAFQNAIPTGNWMYPVANVTLPAGFEQLTKPATTLEFTPAEVAAQRQAWISEWQRAVSR
>NZ_CP046000.1|WP_001389162.1|3930156_3931812_+|HTH-type-transcriptional-regulator-SgrR
MPSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLLNTMQDRGWLTWEAEVGRGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKATVRQMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEENGELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIADIVSPTPWTLDIHLTQPDRWLPLLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRNTTNQLKIQAFDDFFGYRALIDEVNVWVLPEIADEPAGGLMLKGPQGEEKEIESRLEEGCYYLLFDSRTHRGANQQVRDWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHARTIKSEKPTGLESLTLTFYQDHSEHRVIAGIMQQILASQQVTLEIKEIDYDQWHTGEIESDIWLNSANFTLPLDFSVFAHLCEVPLLQHCIPIDWQADAARWRNGEMNLANWCQQLVASKAMVPLLHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDP
>NZ_CP046000.1|WP_001248770.1|3929936_3930068_-|glucose-uptake-inhibitor-SgrT
MRQFYQHYFTATAKLCWLRWLSVPQRLTMLEGLMQWDDRNSES
>NZ_CP046000.1|WP_000637846.1|3928656_3929835_-|sugar-efflux-transporter-SetA
MIWIMTMARRMNGVYAAFMLVAFMMGVAGALQAPTLSLFLSREVGAQPFWIGLFYTVNAIAGIGVSLWLAKRSDSQGDRRKLIIFCCLMAIGNALLFAFNRHYLTLITCGVLLASLANTAMPQLFALAREYADNSAREVVMFSSVMRAQLSLAWVIGPPLAFMLALNYGFTVMFSIAAGIFTLSLVLIAFMLPSVARVELPSENALSMQGGWQDSNVRMLFVASTLMWTCNTMYIIDMPLWISSELGLPDKLAGFLMGTAAGLEIPAMILAGYYVKRYGKRRMMVIAVAAGVLFYTGLIFFHSRMALMTLQLFNAVFIGIVAGIGMLWFQDLMPGRAGAATTLFTNSISTGVILAGVIQGAIAQSWGHFAVYWVIAVISVVALFLTAKVKDV
>NZ_CP046000.1|WP_000888642.1|3940820_3941516_+|L-ribulose-5-phosphate-4-epimerase
MLEDLKRLVLEANLALPKHNLVTLTWGNVSAVDRERGVFVIKPSGVDYSVMTADDMVVVSIATGEVVEGTKKPSSDTPTHRLLYQAFPSIGGIVHTHSRHATIWAQAGQSIPATGTTHADYFYGTIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDAAQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEVAYMGIFCRQLAPQLPDMQQTLLDKHYLRKHGAKAYYGQ
>NZ_CP046000.1|WP_000035639.1|3941590_3943942_+|DNA-polymerase-II
MAQAGFILTRHWRDTPQGTEVSFWLATDNGPLQVTLAPQESVAFIPADQVPRAQHILQGEQGFRLTPLALKDFHRQPVYGLYCRAHRQLMNYEKRLREGGVTVYEADVRPPERYLMERFITSPVWVEGDIRNGAIVNARLKPHPDYRPPLKWVSIDIETTRHGELYCIGLEGCGQRIVYMLGPENGDASALDFELEYVASRPQLLEKLNAWFANYDPDVIIGWNVVQFDLRMLQKHAERYRIPLRLGRDNSELEWREHGFKNGVFFAQAKGRLIIDGIEALKSAFWNFSSFSLETVAQELLGEGKSIDNPWDRMDEIDRRFAEDKPALATYNLKDCELVTQIFHKTEIMPFLLERATVNGLPVDRHGGSVAAFGHLYFPRMHRAGYVAPNLGEVPPHASPGGYVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLVEGMAQPDPEHSTEGFLDAWFSREKHCLPEIVTNIWHGRDEAKRQGNKPLSQALKIIMNAFYGVLGTTACRFFDPRLASSITMRGHQIMRQTKALIETQGYDVIYGDTDSTFVWLKGAHSEEEAAKIGRALVQHVNAWWAETLQKQRLTSALELEYETHFCRFLMPTIRGADTGSKKRYAGLIQEGDKQRMVFKGLETVRTDWTPLAQQFQQELYLRIFRNEPYQEYVRQTIDKLMAGELDARLVYRKRLRRPLSEYQRNVPPHVRAARLADEENQKRGRPLQYQNRGTIKYVWTTNGPEPLDYQRSPLDYEHYLTRQLQPVAEGILPFIEDNFATLMTGQLGLF
>NZ_CP046000.1|WP_001117011.1|3944106_3947013_+|RNA-polymerase-associated-protein-RapA
MPFTLGQRWISDTESELGLGTVVAVDARTVTLLFPSTGENRLYARSDSPVTRVMFNPGDTITSHDGWQMQVEEVKEENGLLTYIGTRLDTEESGVALREVFLDSKLVFSKPQDRLFAGQIDRMDRFALRYRARKYSSEQFRMPYSGLRGQRTSLIPHQLNIAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIIVPETLQHQWLVEMLRRFNLRFALFDDERYAEAQHDAYNPFDTEQLVICSLDFARRSKQRLEHLCEAEWDLLVVDEAHHLVWSEDAPSREYQAIEQLAEHVPGVLLLTATPEQLGMESHFARLRLLDPNRFHDFAQFVEEQKNYRPVADAVAMLLAGNKLSNDELNMLGEMIGEQDIEPLLQAANSDSEDAQSARQELVSMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIKLPLPTQYQTAIKVSGIMGARKSAEDRARDMLYPERIYQEFEGDNATWWNFDPRVEWLMGYLTSHRSQKVLVICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIGSEGRNFQFASHMVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRWYHEGLDAFEHTCPTGRTIYDSVYNDLINYLASPDQTEGFDDLIKNCREQHEALKAQLEQGRDRLLEIHSNGGEKAQALAESIEEQDDDTNLIAFAMNLFDIIGINQDDRGDNMIVLTPSDHMLVPDFPGLSEDGITITFDREVALAREDAQFITWEHPLIRNGLDLILSGDTGSSTISLLKNKALPVGTLLVELIYVVEAQAPKQLQLNRFLPPTPVRMLLDKNGNNLAAQVEFETFNRQLNAVNRHTGSKLVNAVQQDVHAILQLGEAQIEKSARALIDAARNEADEKLSAELSRLEALRAVNPNIRDDELTAIESNRQQVMESLDQAGWRLDALRLIVVTHQ
>NZ_CP046000.1|WP_000525176.1|3947024_3947684_+|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA
MGMENYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDYPQAESVHRLDMATSGVIVVALTKAAERELKRQFREREPKKQYVARVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPADF
>NZ_CP046000.1|WP_001200573.1|3947800_3948616_-|co-chaperone-DjlA
MQYWGKIIGVAVALLMGGGFWGVVLGLLIGHMFDKARSRKMAWFANQRERQALFFATTFEVMGHLTKSKGRVTEADIHIASQLMDRMNLHGASRTAAQNAFRVGKSDNYPLREKMRQFRSVCFGRFDLIRMFLEIQIQAAFADGSLHPNERAVLYVIAEELGISRAQFDQFLRMMQGGAQFGGGYQQQSGGGNWQQAQRGPTLEDACNVLGVKPTDDATTIKRAYRKLMSEHHPDKLVAKGLPPEMMEMAKQKAQEIQQAYELIKQQKGFK
>NZ_CP046000.1|WP_000746150.1|3948870_3951225_+|LPS-assembly-protein-LptD
MKKRIPTLLATMIATALYSQQGLAADLASQCMLGVPSYDRPLVQGDTNDLPVTINADHAKGDYPDDAVFTGSVDIMQGNSRLQADEVQLHQKEAPGQPEPVRTVDALGNVHYDDNQVILKGPKGWANLNTKDTNVWEGDYQMVGRQGRGKADLMKQRGENRYTILDNGSFTSCLPGSDTWSVVGSEIIHDREEQVAEIWNARFKVGPVPIFYSPYLQLPVGDKRRSGFLIPNAKYTTTNYFEFYLPYYWNIAPNMDATITPHYMHRRGNIMWENEFRYLSQAGAGLMELDYLPSDKVYEDEHPNDDSSRRWLFYWNHSGVMDQVWRFNVDYTKVSDPSYFNDFDNKYGSSTDGYATQKFSVGYAVQNFNATVSTKQFQVFSEQNTSSYSAEPQLDVNYYQNDVGPFDTRIYGQAVHFVNTRDDMPEATRVHLEPTINLPLSNNWGSINTEAKLLATHYQQTNLDWYNSRNTTKLDESVNRVMPQFKVDGKMVFERDMEMLAPGYTQTLEPRAQYLYVPYRDQSDIYNYDSSLLQSDYSGLFRDRTYGGLDRIASANQVTTGVTSRIYDDAAVERFNISVGQIYYFTESRTGDDNITWENDDKTGSLVWAGDTYWRISERWGLRGGIQYDTRLDNVATSNSSIEYRRDEDRLVQLNYRYASPEYIQATLPKYYSTAEQYKNGISQVGAVASWPIADRWSIVGAYYYDTNANKQADSMLGVQYSSCCYAIRVGYERKLNGWDNDKQHAVYDNAIGFNIELRGLSSNYGLGTQEMLRSNILPYQNSL
>NZ_CP046000.1|WP_000800453.1|3951277_3952564_+|peptidylprolyl-isomerase-SurA
MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDGLMQSVKLNAAQARQQLPDDATLRHQIMERLIMDQIILQMGQKMGVKISDEQLDQAIANIAKQNNMTLDQMRSRLAYDGLNYNTYRNQIRKEMIISEVRNNEVRRRITILPQEVESLAQQVGNQNDASTELNLSHILIPLPENPTSDQVNEAESQARAIVDQARNGADFGKLAIAHSADQQALNGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGESKNISVTEVHARHILLKPSPIMTDEQARVKLEQIAADIKSGKTTFAAAAKEFSQDPGSANQGGDLGWATADIFDPAFRDALTRLNKGQMSAPVHSSFGWHLIELLDTRNVDKTDAAQKDRAYRMLMNRKFSEEAASWMQEQRASAYVKILSN
>NZ_CP046000.1|WP_000241271.1|3952563_3953553_+|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA
MVKTQRVVITPGEPAGIGPDLVVQLAQREWPVELVVCADATLLTDRAAMLGLPLTLRTYSPNSPAQPQTAGTLTLLPVALRESVTAGQLAVENGHYVVETLARACDGCLNGEFAALITGPVHKGVINDAGIPFTGHTEFFEERSQAKKVVMMLATEELRVALATTHLPLRDIADAITPALLHEVIAILHHDLRTKFGIAEPRILVCGLNPHAGEGGHMGTEEIDTIIPLLDELRAQGMKLNGPLPADTLFQPKYLDNADAVLAMYHDQGLPVLKYQGFGRGVNITLGLPFIRTSVDHGTALELAGRGEADVGSFITALNLAIKMIVNTQ
>NZ_CP046000.1|WP_025653143.1|3953549_3954371_+|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA
MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEIGPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTFNFGELAEKMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRLSVMAQYYCNVIPVLEVPPSAFTPPPKVDSAVVRLVPHATMPHPVKDVRVLSRITTEAFNQRRKTIRNSLGNLFSVEVFIGMGIDPAMRAENISVAQYCQMANYLAENAPLQES
>NZ_CP046000.1|WP_000610901.1|3954373_3954751_+|Co2+/Mg2+-efflux-protein-ApaG
MINSPRVCIQVQSVYIEAQSSPDNERYVFAYTVTIRNLGRAPVQLLGRYWLITNGNGRETEVQGEGVVGVQPLIAPGEEYQYTSGAIIETPLGTMQGHYEMIDENGVPFSIDIPVFRLAVPTLIH

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP046000_4	4.1\|2240629\|38\|NZ_CP046000\|CRISPRCasFinder	2240629-2240666	38	NZ_CP043437	Enterobacter sp. LU1 plasmid unnamed	113727-113764	2	0.947
NZ_CP046000_3	3.12\|1094283\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1094283-1094314	32	NZ_CP015609	Bacillus safensis strain U14-5 plasmid unnamed2, complete sequence	10946-10977	6	0.812
NZ_CP046000_3	3.12\|1094283\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1094283-1094314	32	NZ_CP025188	Roseomonas mucosa strain AD2 plasmid p1-AD2, complete sequence	305380-305411	6	0.812
NZ_CP046000_3	3.15\|1094466\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1094466-1094497	32	CP000662	Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA01, complete sequence	649166-649197	6	0.812
NZ_CP046000_3	3.16\|1094527\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1094527-1094558	32	NZ_CP050442	Tolypothrix sp. PCC 7910 plasmid unnamed2, complete sequence	41503-41534	6	0.812
NZ_CP046000_2	2.4\|1067804\|32\|NZ_CP046000\|CRISPRCasFinder,CRT	1067804-1067835	32	KR080197	Mycobacterium phage FlagStaff, complete genome	15476-15507	7	0.781
NZ_CP046000_3	3.11\|1094222\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1094222-1094253	32	NZ_AP014659	Bradyrhizobium diazoefficiens strain NK6 plasmid pNK6a, complete sequence	89317-89348	7	0.781
NZ_CP046000_3	3.11\|1094222\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1094222-1094253	32	NZ_AP014659	Bradyrhizobium diazoefficiens strain NK6 plasmid pNK6a, complete sequence	149653-149684	7	0.781
NZ_CP046000_3	3.11\|1094222\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1094222-1094253	32	NZ_AP014686	Bradyrhizobium diazoefficiens strain NK6 plasmid pNK6b, complete sequence	101093-101124	7	0.781
NZ_CP046000_3	3.11\|1094222\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1094222-1094253	32	NZ_AP014686	Bradyrhizobium diazoefficiens strain NK6 plasmid pNK6b, complete sequence	141992-142023	7	0.781
NZ_CP046000_3	3.11\|1094222\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1094222-1094253	32	NZ_AP014688	Bradyrhizobium diazoefficiens strain NK6 plasmid pNK6d, complete sequence	99321-99352	7	0.781
NZ_CP046000_3	3.11\|1094222\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1094222-1094253	32	NZ_CP049700	Bradyrhizobium sp. 1S5 strain 323S2 plasmid pB323S2a, complete sequence	142212-142243	7	0.781
NZ_CP046000_3	3.11\|1094222\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1094222-1094253	32	NZ_CP049700	Bradyrhizobium sp. 1S5 strain 323S2 plasmid pB323S2a, complete sequence	161765-161796	7	0.781
NZ_CP046000_3	3.11\|1094222\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1094222-1094253	32	NZ_CP049700	Bradyrhizobium sp. 1S5 strain 323S2 plasmid pB323S2a, complete sequence	175817-175848	7	0.781
NZ_CP046000_3	3.11\|1094222\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1094222-1094253	32	NZ_CP049701	Bradyrhizobium sp. 1S5 strain 323S2 plasmid pB323S2b, complete sequence	140186-140217	7	0.781
NZ_CP046000_3	3.11\|1094222\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1094222-1094253	32	NZ_CP049701	Bradyrhizobium sp. 1S5 strain 323S2 plasmid pB323S2b, complete sequence	188728-188759	7	0.781
NZ_CP046000_3	3.11\|1094222\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1094222-1094253	32	NZ_CP049701	Bradyrhizobium sp. 1S5 strain 323S2 plasmid pB323S2b, complete sequence	267789-267820	7	0.781
NZ_CP046000_3	3.11\|1094222\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1094222-1094253	32	NZ_CP049702	Bradyrhizobium sp. 1S5 strain 323S2 plasmid pB323S2c, complete sequence	70012-70043	7	0.781
NZ_CP046000_2	2.2\|1067682\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1067682-1067713	32	NZ_KY433363	Proteus mirabilis strain R997 plasmid pR997, complete sequence	57742-57773	8	0.75
NZ_CP046000_2	2.4\|1067804\|32\|NZ_CP046000\|CRISPRCasFinder,CRT	1067804-1067835	32	NZ_CP014600	Yangia sp. CCB-MM3 plasmid unnamed4, complete sequence	15418-15449	8	0.75
NZ_CP046000_3	3.4\|1093794\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1093794-1093825	32	CP023013	Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence	1077804-1077835	8	0.75
NZ_CP046000_3	3.4\|1093794\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1093794-1093825	32	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	1081182-1081213	8	0.75
NZ_CP046000_3	3.4\|1093794\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1093794-1093825	32	NZ_CP015851	Ralstonia solanacearum strain YC40-M plasmid, complete sequence	1264658-1264689	8	0.75
NZ_CP046000_3	3.4\|1093794\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1093794-1093825	32	NZ_CP022783	Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence	1083481-1083512	8	0.75
NZ_CP046000_3	3.4\|1093794\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1093794-1093825	32	NZ_CP022795	Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence	1080184-1080215	8	0.75
NZ_CP046000_3	3.4\|1093794\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1093794-1093825	32	CP023015	Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence	909207-909238	8	0.75
NZ_CP046000_3	3.4\|1093794\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1093794-1093825	32	NZ_CP052077	Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence	1059848-1059879	8	0.75
NZ_CP046000_3	3.4\|1093794\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1093794-1093825	32	NZ_CP052079	Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence	1059871-1059902	8	0.75
NZ_CP046000_3	3.4\|1093794\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1093794-1093825	32	NZ_CP052125	Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence	1059871-1059902	8	0.75
NZ_CP046000_3	3.4\|1093794\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1093794-1093825	32	NZ_CP052123	Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence	1059871-1059902	8	0.75
NZ_CP046000_3	3.4\|1093794\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1093794-1093825	32	NZ_CP052081	Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence	1059871-1059902	8	0.75
NZ_CP046000_3	3.4\|1093794\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1093794-1093825	32	NZ_CP052083	Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence	1059871-1059902	8	0.75
NZ_CP046000_3	3.6\|1093916\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1093916-1093947	32	CP023013	Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence	1077804-1077835	8	0.75
NZ_CP046000_3	3.6\|1093916\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1093916-1093947	32	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	1081182-1081213	8	0.75
NZ_CP046000_3	3.6\|1093916\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1093916-1093947	32	NZ_CP015851	Ralstonia solanacearum strain YC40-M plasmid, complete sequence	1264658-1264689	8	0.75
NZ_CP046000_3	3.6\|1093916\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1093916-1093947	32	NZ_CP022783	Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence	1083481-1083512	8	0.75
NZ_CP046000_3	3.6\|1093916\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1093916-1093947	32	NZ_CP022795	Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence	1080184-1080215	8	0.75
NZ_CP046000_3	3.6\|1093916\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1093916-1093947	32	CP023015	Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence	909207-909238	8	0.75
NZ_CP046000_3	3.6\|1093916\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1093916-1093947	32	NZ_CP052077	Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence	1059848-1059879	8	0.75
NZ_CP046000_3	3.6\|1093916\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1093916-1093947	32	NZ_CP052079	Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence	1059871-1059902	8	0.75
NZ_CP046000_3	3.6\|1093916\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1093916-1093947	32	NZ_CP052125	Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence	1059871-1059902	8	0.75
NZ_CP046000_3	3.6\|1093916\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1093916-1093947	32	NZ_CP052123	Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence	1059871-1059902	8	0.75
NZ_CP046000_3	3.6\|1093916\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1093916-1093947	32	NZ_CP052081	Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence	1059871-1059902	8	0.75
NZ_CP046000_3	3.6\|1093916\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1093916-1093947	32	NZ_CP052083	Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence	1059871-1059902	8	0.75
NZ_CP046000_3	3.11\|1094222\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1094222-1094253	32	KT221034	Streptomyces phage SF3, complete genome	42881-42912	8	0.75
NZ_CP046000_3	3.11\|1094222\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1094222-1094253	32	NC_008270	Rhodococcus jostii RHA1 plasmid pRHL2, complete sequence	149701-149732	8	0.75
NZ_CP046000_3	3.11\|1094222\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1094222-1094253	32	NZ_CP017563	Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence	797644-797675	8	0.75
NZ_CP046000_3	3.15\|1094466\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1094466-1094497	32	MT889371	Microbacterium phage DelaGarza, complete genome	35549-35580	8	0.75
NZ_CP046000_2	2.1\|1067621\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1067621-1067652	32	NZ_CP030864	Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence	52197-52228	9	0.719
NZ_CP046000_2	2.2\|1067682\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1067682-1067713	32	NZ_KX528687	Acinetobacter lwoffii strain ED9-5a plasmid pALWED3.1, complete sequence	60757-60788	9	0.719
NZ_CP046000_2	2.2\|1067682\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1067682-1067713	32	NZ_CP031977	Acinetobacter haemolyticus strain AN43 plasmid pAhaemAN43b, complete sequence	41217-41248	9	0.719
NZ_CP046000_2	2.2\|1067682\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1067682-1067713	32	NZ_CP018638	Salmonella enterica subsp. enterica serovar Enteritidis strain 69-3861 plasmid pSE69-3861-1, complete sequence	697-728	9	0.719
NZ_CP046000_2	2.2\|1067682\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1067682-1067713	32	NZ_CP031973	Acinetobacter haemolyticus strain AN59 plasmid pAhaemAN59c, complete sequence	41217-41248	9	0.719
NZ_CP046000_2	2.2\|1067682\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1067682-1067713	32	NZ_CP045203	Citrobacter sp. NMI7904_11 plasmid pCTEL-2, complete sequence	184766-184797	9	0.719
NZ_CP046000_2	2.2\|1067682\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1067682-1067713	32	NZ_CP021429	Acinetobacter pittii strain HUMV-6483 plasmid p11, complete sequence	54225-54256	9	0.719
NZ_CP046000_2	2.2\|1067682\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1067682-1067713	32	NZ_CP040913	Acinetobacter pittii strain AB17H194 plasmid pAB17H194-2, complete sequence	46038-46069	9	0.719
NZ_CP046000_2	2.2\|1067682\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1067682-1067713	32	NZ_CP030755	Acinetobacter schindleri strain H3 plasmid unnamed1, complete sequence	51662-51693	9	0.719
NZ_CP046000_2	2.2\|1067682\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1067682-1067713	32	CP033526	Acinetobacter pittii strain 2014N05-125 plasmid p2014N05-125-1, complete sequence	26822-26853	9	0.719
NZ_CP046000_2	2.2\|1067682\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1067682-1067713	32	NZ_CP025619	Acinetobacter schindleri strain SGAir0122 plasmid pSGAir0122, complete sequence	145953-145984	9	0.719
NZ_CP046000_2	2.4\|1067804\|32\|NZ_CP046000\|CRISPRCasFinder,CRT	1067804-1067835	32	NZ_CP009292	Novosphingobium pentaromativorans US6-1 plasmid pLA3, complete sequence	139210-139241	9	0.719
NZ_CP046000_3	3.4\|1093794\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1093794-1093825	32	NZ_CP019604	Croceicoccus marinus strain E4A9 plasmid pCME4A9II, complete sequence	45733-45764	9	0.719
NZ_CP046000_3	3.4\|1093794\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1093794-1093825	32	NZ_CP025432	Paracoccus zhejiangensis strain J6 plasmid pPZ02, complete sequence	92571-92602	9	0.719
NZ_CP046000_3	3.4\|1093794\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1093794-1093825	32	AY526908	Bordetella phage BMP-1, complete genome	4333-4364	9	0.719
NZ_CP046000_3	3.4\|1093794\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1093794-1093825	32	NC_005357	Bordetella phage BPP-1, complete genome	4333-4364	9	0.719
NZ_CP046000_3	3.4\|1093794\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1093794-1093825	32	AY526909	Bordetella phage BIP-1, complete genome	4333-4364	9	0.719
NZ_CP046000_3	3.6\|1093916\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1093916-1093947	32	NZ_CP019604	Croceicoccus marinus strain E4A9 plasmid pCME4A9II, complete sequence	45733-45764	9	0.719
NZ_CP046000_3	3.6\|1093916\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1093916-1093947	32	NZ_CP025432	Paracoccus zhejiangensis strain J6 plasmid pPZ02, complete sequence	92571-92602	9	0.719
NZ_CP046000_3	3.6\|1093916\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1093916-1093947	32	AY526908	Bordetella phage BMP-1, complete genome	4333-4364	9	0.719
NZ_CP046000_3	3.6\|1093916\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1093916-1093947	32	NC_005357	Bordetella phage BPP-1, complete genome	4333-4364	9	0.719
NZ_CP046000_3	3.6\|1093916\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1093916-1093947	32	AY526909	Bordetella phage BIP-1, complete genome	4333-4364	9	0.719
NZ_CP046000_3	3.11\|1094222\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1094222-1094253	32	JN698994	Mycobacterium phage DS6A, complete genome	24764-24795	9	0.719
NZ_CP046000_3	3.15\|1094466\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1094466-1094497	32	NZ_CP044425	Paracoccus pantotrophus strain DSM 2944 plasmid pPAN2, complete sequence	203634-203665	9	0.719
NZ_CP046000_2	2.4\|1067804\|32\|NZ_CP046000\|CRISPRCasFinder,CRT	1067804-1067835	32	NZ_CP012383	Streptomyces ambofaciens ATCC 23877 plasmid pSAM1, complete sequence	14130-14161	10	0.688
NZ_CP046000_3	3.4\|1093794\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1093794-1093825	32	NZ_CP025433	Paracoccus zhejiangensis strain J6 plasmid pPZ03, complete sequence	97047-97078	10	0.688
NZ_CP046000_3	3.6\|1093916\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1093916-1093947	32	NZ_CP025433	Paracoccus zhejiangensis strain J6 plasmid pPZ03, complete sequence	97047-97078	10	0.688
NZ_CP046000_3	3.11\|1094222\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1094222-1094253	32	NC_005241	Cupriavidus necator H16 megaplasmid pHG1, complete sequence	74612-74643	10	0.688
NZ_CP046000_3	3.11\|1094222\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1094222-1094253	32	NZ_CP039289	Cupriavidus necator H16 plasmid pHG1, complete sequence	74612-74643	10	0.688
NZ_CP046000_3	3.11\|1094222\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1094222-1094253	32	NC_030916	Tsukamurella phage TPA4, complete genome	18471-18502	10	0.688
NZ_CP046000_3	3.11\|1094222\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1094222-1094253	32	AB276040	Ralstonia phage RSA1 DNA, complete genome	989-1020	10	0.688
NZ_CP046000_3	3.11\|1094222\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1094222-1094253	32	NC_009382	Ralstonia phage phiRSA1, complete genome	989-1020	10	0.688
NZ_CP046000_3	3.12\|1094283\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1094283-1094314	32	LN997844	Streptomyces reticuli genome assembly TUE45, plasmid : III	74068-74099	10	0.688
NZ_CP046000_3	3.11\|1094222\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1094222-1094253	32	NC_007974	Cupriavidus metallidurans CH34 megaplasmid, complete sequence	524692-524723	11	0.656
NZ_CP046000_3	3.11\|1094222\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1094222-1094253	32	NZ_CP017947	Bosea sp. Tri-49 plasmid unnamed1, complete sequence	315738-315769	11	0.656
NZ_CP046000_3	3.11\|1094222\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1094222-1094253	32	NZ_CP046333	Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3	522528-522559	11	0.656
NZ_CP046000_3	3.11\|1094222\|32\|NZ_CP046000\|PILER-CR,CRISPRCasFinder,CRT	1094222-1094253	32	NZ_CP033582	Streptomyces sp. ADI95-16 plasmid pADI95-16a, complete sequence	357216-357247	11	0.656

1. spacer 4.1|2240629|38|NZ_CP046000|CRISPRCasFinder matches to NZ_CP043437 (Enterobacter sp. LU1 plasmid unnamed) position: , mismatch: 2, identity: 0.947

cggacgcaggatggtgcgttcaattggactcgaaccaa	CRISPR spacer
cagacgcagaatggtgcgttcaattggactcgaaccaa	Protospacer
*.*******.****************************

2. spacer 3.12|1094283|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015609 (Bacillus safensis strain U14-5 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.812

gactcaaccgcgcttcccggcctcaccactgc	CRISPR spacer
gcggcaaccgcgcttcccggcctgaccaatcc	Protospacer
*   ******************* **** * *

3. spacer 3.12|1094283|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025188 (Roseomonas mucosa strain AD2 plasmid p1-AD2, complete sequence) position: , mismatch: 6, identity: 0.812

gactcaaccgcgcttcccggcctcaccactgc	CRISPR spacer
gcggcaaccgcgcttcccggcctgaccaatcc	Protospacer
*   ******************* **** * *

4. spacer 3.15|1094466|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to CP000662 (Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA01, complete sequence) position: , mismatch: 6, identity: 0.812

gcaatttgttgtccgcgatccggtacgcgcgt	CRISPR spacer
tcagcttgttgtccgcgatgcggtacgcccgc	Protospacer
 **..************** ******** **.

5. spacer 3.16|1094527|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP050442 (Tolypothrix sp. PCC 7910 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.812

cggctatggaatttatggagaagtttggtttt	CRISPR spacer
ctcctatggaatttatgcagaagtttagtaat	Protospacer
*  ************** ********.**  *

6. spacer 2.4|1067804|32|NZ_CP046000|CRISPRCasFinder,CRT matches to KR080197 (Mycobacterium phage FlagStaff, complete genome) position: , mismatch: 7, identity: 0.781

gacgccgccgccgcgaagccgtttccgatgtt	CRISPR spacer
gacgccggcgccgcgatgccgttcgccgggtt	Protospacer
******* ******** ******. * . ***

7. spacer 3.11|1094222|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP014659 (Bradyrhizobium diazoefficiens strain NK6 plasmid pNK6a, complete sequence) position: , mismatch: 7, identity: 0.781

acgaaaatcgccgccggtgtcctcgctgatca-	CRISPR spacer
ttgaaaatcgccgcccgtgtcgtcg-agaccac	Protospacer
 .************* ***** ***  **.**

8. spacer 3.11|1094222|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP014659 (Bradyrhizobium diazoefficiens strain NK6 plasmid pNK6a, complete sequence) position: , mismatch: 7, identity: 0.781

acgaaaatcgccgccggtgtcctcgctgatca-	CRISPR spacer
ttgaaaatcgccgcccgtgtcgtcg-agaccac	Protospacer
 .************* ***** ***  **.**

9. spacer 3.11|1094222|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP014686 (Bradyrhizobium diazoefficiens strain NK6 plasmid pNK6b, complete sequence) position: , mismatch: 7, identity: 0.781

acgaaaatcgccgccggtgtcctcgctgatca-	CRISPR spacer
ttgaaaatcgccgcccgtgtcgtcg-agaccac	Protospacer
 .************* ***** ***  **.**

10. spacer 3.11|1094222|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP014686 (Bradyrhizobium diazoefficiens strain NK6 plasmid pNK6b, complete sequence) position: , mismatch: 7, identity: 0.781

acgaaaatcgccgccggtgtcctcgctgatca-	CRISPR spacer
ttgaaaatcgccgcccgtgtcgtcg-agaccac	Protospacer
 .************* ***** ***  **.**

11. spacer 3.11|1094222|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP014688 (Bradyrhizobium diazoefficiens strain NK6 plasmid pNK6d, complete sequence) position: , mismatch: 7, identity: 0.781

acgaaaatcgccgccggtgtcctcgctgatca-	CRISPR spacer
ttgaaaatcgccgcccgtgtcgtcg-agaccac	Protospacer
 .************* ***** ***  **.**

12. spacer 3.11|1094222|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP049700 (Bradyrhizobium sp. 1S5 strain 323S2 plasmid pB323S2a, complete sequence) position: , mismatch: 7, identity: 0.781

acgaaaatcgccgccggtgtcctcgctgatca-	CRISPR spacer
ttgaaaatcgccgcccgtgtcgtcg-agaccac	Protospacer
 .************* ***** ***  **.**

13. spacer 3.11|1094222|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP049700 (Bradyrhizobium sp. 1S5 strain 323S2 plasmid pB323S2a, complete sequence) position: , mismatch: 7, identity: 0.781

acgaaaatcgccgccggtgtcctcgctgatca-	CRISPR spacer
ttgaaaatcgccgcccgtgtcgtcg-agaccac	Protospacer
 .************* ***** ***  **.**

14. spacer 3.11|1094222|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP049700 (Bradyrhizobium sp. 1S5 strain 323S2 plasmid pB323S2a, complete sequence) position: , mismatch: 7, identity: 0.781

acgaaaatcgccgccggtgtcctcgctgatca-	CRISPR spacer
ttgaaaatcgccgcccgtgtcgtcg-agaccac	Protospacer
 .************* ***** ***  **.**

15. spacer 3.11|1094222|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP049701 (Bradyrhizobium sp. 1S5 strain 323S2 plasmid pB323S2b, complete sequence) position: , mismatch: 7, identity: 0.781

acgaaaatcgccgccggtgtcctcgctgatca-	CRISPR spacer
ttgaaaatcgccgcccgtgtcgtcg-agaccac	Protospacer
 .************* ***** ***  **.**

16. spacer 3.11|1094222|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP049701 (Bradyrhizobium sp. 1S5 strain 323S2 plasmid pB323S2b, complete sequence) position: , mismatch: 7, identity: 0.781

acgaaaatcgccgccggtgtcctcgctgatca-	CRISPR spacer
ttgaaaatcgccgcccgtgtcgtcg-agaccac	Protospacer
 .************* ***** ***  **.**

17. spacer 3.11|1094222|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP049701 (Bradyrhizobium sp. 1S5 strain 323S2 plasmid pB323S2b, complete sequence) position: , mismatch: 7, identity: 0.781

acgaaaatcgccgccggtgtcctcgctgatca-	CRISPR spacer
ttgaaaatcgccgcccgtgtcgtcg-agaccac	Protospacer
 .************* ***** ***  **.**

18. spacer 3.11|1094222|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP049702 (Bradyrhizobium sp. 1S5 strain 323S2 plasmid pB323S2c, complete sequence) position: , mismatch: 7, identity: 0.781

acgaaaatcgccgccggtgtcctcgctgatca-	CRISPR spacer
ttgaaaatcgccgcccgtgtcgtcg-agaccac	Protospacer
 .************* ***** ***  **.**

19. spacer 2.2|1067682|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KY433363 (Proteus mirabilis strain R997 plasmid pR997, complete sequence) position: , mismatch: 8, identity: 0.75

atgatttttgcacgacgttcaaccggcgtttc	CRISPR spacer
ctccatcatgcacgaccttcaaccggcggttc	Protospacer
 *   *. ******** *********** ***

20. spacer 2.4|1067804|32|NZ_CP046000|CRISPRCasFinder,CRT matches to NZ_CP014600 (Yangia sp. CCB-MM3 plasmid unnamed4, complete sequence) position: , mismatch: 8, identity: 0.75

gacgccgccgccgcgaagccgtttccgatgtt	CRISPR spacer
gtcgccgccgccgcgcagccctttccacagcc	Protospacer
* ************* **** *****.  *..

21. spacer 3.4|1093794|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to CP023013 (Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gaatatcgggtgccagcctggacgctggccga	CRISPR spacer
gaggatcgggcgccagcctgcacgctgctggt	Protospacer
**. ******.********* ****** . *

22. spacer 3.4|1093794|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gaatatcgggtgccagcctggacgctggccga	CRISPR spacer
gaggatcgggcgccagcctgcacgctgctggt	Protospacer
**. ******.********* ****** . *

23. spacer 3.4|1093794|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015851 (Ralstonia solanacearum strain YC40-M plasmid, complete sequence) position: , mismatch: 8, identity: 0.75

gaatatcgggtgccagcctggacgctggccga	CRISPR spacer
gaggatcgggcgccagcctgcacgctgctggt	Protospacer
**. ******.********* ****** . *

24. spacer 3.4|1093794|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022783 (Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gaatatcgggtgccagcctggacgctggccga	CRISPR spacer
gaggatcgggcgccagcctgcacgctgctggt	Protospacer
**. ******.********* ****** . *

25. spacer 3.4|1093794|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022795 (Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gaatatcgggtgccagcctggacgctggccga	CRISPR spacer
gaggatcgggcgccagcctgcacgctgctggt	Protospacer
**. ******.********* ****** . *

26. spacer 3.4|1093794|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to CP023015 (Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gaatatcgggtgccagcctggacgctggccga	CRISPR spacer
gaggatcgggcgccagcctgcacgctgctggt	Protospacer
**. ******.********* ****** . *

27. spacer 3.4|1093794|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP052077 (Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.75

gaatatcgggtgccagcctggacgctggccga	CRISPR spacer
gaggatcgggcgccagcctgcacgctgctggt	Protospacer
**. ******.********* ****** . *

28. spacer 3.4|1093794|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP052079 (Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.75

gaatatcgggtgccagcctggacgctggccga	CRISPR spacer
gaggatcgggcgccagcctgcacgctgctggt	Protospacer
**. ******.********* ****** . *

29. spacer 3.4|1093794|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP052125 (Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.75

gaatatcgggtgccagcctggacgctggccga	CRISPR spacer
gaggatcgggcgccagcctgcacgctgctggt	Protospacer
**. ******.********* ****** . *

30. spacer 3.4|1093794|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP052123 (Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.75

gaatatcgggtgccagcctggacgctggccga	CRISPR spacer
gaggatcgggcgccagcctgcacgctgctggt	Protospacer
**. ******.********* ****** . *

31. spacer 3.4|1093794|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP052081 (Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.75

gaatatcgggtgccagcctggacgctggccga	CRISPR spacer
gaggatcgggcgccagcctgcacgctgctggt	Protospacer
**. ******.********* ****** . *

32. spacer 3.4|1093794|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP052083 (Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.75

gaatatcgggtgccagcctggacgctggccga	CRISPR spacer
gaggatcgggcgccagcctgcacgctgctggt	Protospacer
**. ******.********* ****** . *

33. spacer 3.6|1093916|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to CP023013 (Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gaatatcgggtgccagcctggacgctggccga	CRISPR spacer
gaggatcgggcgccagcctgcacgctgctggt	Protospacer
**. ******.********* ****** . *

34. spacer 3.6|1093916|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gaatatcgggtgccagcctggacgctggccga	CRISPR spacer
gaggatcgggcgccagcctgcacgctgctggt	Protospacer
**. ******.********* ****** . *

35. spacer 3.6|1093916|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015851 (Ralstonia solanacearum strain YC40-M plasmid, complete sequence) position: , mismatch: 8, identity: 0.75

gaatatcgggtgccagcctggacgctggccga	CRISPR spacer
gaggatcgggcgccagcctgcacgctgctggt	Protospacer
**. ******.********* ****** . *

36. spacer 3.6|1093916|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022783 (Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gaatatcgggtgccagcctggacgctggccga	CRISPR spacer
gaggatcgggcgccagcctgcacgctgctggt	Protospacer
**. ******.********* ****** . *

37. spacer 3.6|1093916|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022795 (Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gaatatcgggtgccagcctggacgctggccga	CRISPR spacer
gaggatcgggcgccagcctgcacgctgctggt	Protospacer
**. ******.********* ****** . *

38. spacer 3.6|1093916|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to CP023015 (Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gaatatcgggtgccagcctggacgctggccga	CRISPR spacer
gaggatcgggcgccagcctgcacgctgctggt	Protospacer
**. ******.********* ****** . *

39. spacer 3.6|1093916|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP052077 (Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.75

gaatatcgggtgccagcctggacgctggccga	CRISPR spacer
gaggatcgggcgccagcctgcacgctgctggt	Protospacer
**. ******.********* ****** . *

40. spacer 3.6|1093916|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP052079 (Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.75

gaatatcgggtgccagcctggacgctggccga	CRISPR spacer
gaggatcgggcgccagcctgcacgctgctggt	Protospacer
**. ******.********* ****** . *

41. spacer 3.6|1093916|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP052125 (Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.75

gaatatcgggtgccagcctggacgctggccga	CRISPR spacer
gaggatcgggcgccagcctgcacgctgctggt	Protospacer
**. ******.********* ****** . *

42. spacer 3.6|1093916|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP052123 (Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.75

gaatatcgggtgccagcctggacgctggccga	CRISPR spacer
gaggatcgggcgccagcctgcacgctgctggt	Protospacer
**. ******.********* ****** . *

43. spacer 3.6|1093916|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP052081 (Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.75

gaatatcgggtgccagcctggacgctggccga	CRISPR spacer
gaggatcgggcgccagcctgcacgctgctggt	Protospacer
**. ******.********* ****** . *

44. spacer 3.6|1093916|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP052083 (Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.75

gaatatcgggtgccagcctggacgctggccga	CRISPR spacer
gaggatcgggcgccagcctgcacgctgctggt	Protospacer
**. ******.********* ****** . *

45. spacer 3.11|1094222|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to KT221034 (Streptomyces phage SF3, complete genome) position: , mismatch: 8, identity: 0.75

acgaaaatcgccgccggtgtcctcgctgatca	CRISPR spacer
gtacagctcgtcgccggtgtcctcgcggatca	Protospacer
... *. ***.*************** *****

46. spacer 3.11|1094222|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NC_008270 (Rhodococcus jostii RHA1 plasmid pRHL2, complete sequence) position: , mismatch: 8, identity: 0.75

acgaaaatcgccgccggtgtcctcgctgatca	CRISPR spacer
gccgtagccgccgccggtgccctggctgatca	Protospacer
.* . *..***********.*** ********

47. spacer 3.11|1094222|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017563 (Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence) position: , mismatch: 8, identity: 0.75

----acgaaaatcgccgccggtgtcctcgctgatca	CRISPR spacer
ggccgcga----tgccgtcggtgtccttgctgatca	Protospacer
    .***    .****.*********.********

48. spacer 3.15|1094466|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to MT889371 (Microbacterium phage DelaGarza, complete genome) position: , mismatch: 8, identity: 0.75

gcaatttgttgtccgcgatccggtacgcgcgt	CRISPR spacer
ccgtgcggttgtccgcgatccggtaggcgcgc	Protospacer
 *.  . ****************** *****.

49. spacer 2.1|1067621|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030864 (Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

ccgatcacacgctcccacgggccgtaccagtc	CRISPR spacer
ttcggcagccgctcccaccggccggaccagtc	Protospacer
.. . **  ********* ***** *******

50. spacer 2.2|1067682|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KX528687 (Acinetobacter lwoffii strain ED9-5a plasmid pALWED3.1, complete sequence) position: , mismatch: 9, identity: 0.719

atgatttttgcacgacgttcaaccggcgtttc	CRISPR spacer
caccgtcatgcacgaccttcaaccggcggttc	Protospacer
     *. ******** *********** ***

51. spacer 2.2|1067682|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP031977 (Acinetobacter haemolyticus strain AN43 plasmid pAhaemAN43b, complete sequence) position: , mismatch: 9, identity: 0.719

atgatttttgcacgacgttcaaccggcgtttc	CRISPR spacer
caccgtcatgcacgaccttcaaccggcggttc	Protospacer
     *. ******** *********** ***

52. spacer 2.2|1067682|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018638 (Salmonella enterica subsp. enterica serovar Enteritidis strain 69-3861 plasmid pSE69-3861-1, complete sequence) position: , mismatch: 9, identity: 0.719

atgatttttgcacgacgttcaaccggcgtttc	CRISPR spacer
caccgtcatgcacgaccttcaaccggcggttc	Protospacer
     *. ******** *********** ***

53. spacer 2.2|1067682|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP031973 (Acinetobacter haemolyticus strain AN59 plasmid pAhaemAN59c, complete sequence) position: , mismatch: 9, identity: 0.719

atgatttttgcacgacgttcaaccggcgtttc	CRISPR spacer
caccgtcatgcacgaccttcaaccggcggttc	Protospacer
     *. ******** *********** ***

54. spacer 2.2|1067682|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045203 (Citrobacter sp. NMI7904_11 plasmid pCTEL-2, complete sequence) position: , mismatch: 9, identity: 0.719

atgatttttgcacgacgttcaaccggcgtttc	CRISPR spacer
cgccgtcatgcacgaccttcaaccggcggttc	Protospacer
     *. ******** *********** ***

55. spacer 2.2|1067682|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021429 (Acinetobacter pittii strain HUMV-6483 plasmid p11, complete sequence) position: , mismatch: 9, identity: 0.719

atgatttttgcacgacgttcaaccggcgtttc	CRISPR spacer
caccgtcatgcacgaccttcaaccggcggttc	Protospacer
     *. ******** *********** ***

56. spacer 2.2|1067682|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040913 (Acinetobacter pittii strain AB17H194 plasmid pAB17H194-2, complete sequence) position: , mismatch: 9, identity: 0.719

atgatttttgcacgacgttcaaccggcgtttc	CRISPR spacer
caccgtcatgcacgaccttcaaccggcggttc	Protospacer
     *. ******** *********** ***

57. spacer 2.2|1067682|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030755 (Acinetobacter schindleri strain H3 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

atgatttttgcacgacgttcaaccggcgtttc	CRISPR spacer
caccgtcatgcacgaccttcaaccggcggttc	Protospacer
     *. ******** *********** ***

58. spacer 2.2|1067682|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to CP033526 (Acinetobacter pittii strain 2014N05-125 plasmid p2014N05-125-1, complete sequence) position: , mismatch: 9, identity: 0.719

atgatttttgcacgacgttcaaccggcgtttc	CRISPR spacer
caccgtcatgcacgaccttcaaccggcggttc	Protospacer
     *. ******** *********** ***

59. spacer 2.2|1067682|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025619 (Acinetobacter schindleri strain SGAir0122 plasmid pSGAir0122, complete sequence) position: , mismatch: 9, identity: 0.719

atgatttttgcacgacgttcaaccggcgtttc	CRISPR spacer
cgccgtcatgcacgaccttcaaccggcggttc	Protospacer
     *. ******** *********** ***

60. spacer 2.4|1067804|32|NZ_CP046000|CRISPRCasFinder,CRT matches to NZ_CP009292 (Novosphingobium pentaromativorans US6-1 plasmid pLA3, complete sequence) position: , mismatch: 9, identity: 0.719

gacgccgccgccgcgaagccgtttccgatgtt	CRISPR spacer
gaagccgccgccgcgaacccgtttttcccggg	Protospacer
** ************** ******..  .*

61. spacer 3.4|1093794|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019604 (Croceicoccus marinus strain E4A9 plasmid pCME4A9II, complete sequence) position: , mismatch: 9, identity: 0.719

gaatatcgggtgccagcctggacgctggccga	CRISPR spacer
caacatcgggtggcagcctggacgtgtcgcgc	Protospacer
 **.******** ***********.    **

62. spacer 3.4|1093794|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025432 (Paracoccus zhejiangensis strain J6 plasmid pPZ02, complete sequence) position: , mismatch: 9, identity: 0.719

gaatatcgggtgccagcctggacgctggccga	CRISPR spacer
caaaccggggtgccagcctcgatgctggccat	Protospacer
 **  . ************ **.*******.

63. spacer 3.4|1093794|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to AY526908 (Bordetella phage BMP-1, complete genome) position: , mismatch: 9, identity: 0.719

----gaatatcgggtgccagcctggacgctggccga	CRISPR spacer
tccacgat----ggtgccagccttgatgctggccgt	Protospacer
     .**    *********** **.********

64. spacer 3.4|1093794|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NC_005357 (Bordetella phage BPP-1, complete genome) position: , mismatch: 9, identity: 0.719

----gaatatcgggtgccagcctggacgctggccga	CRISPR spacer
tccacgat----ggtgccagccttgatgctggccgt	Protospacer
     .**    *********** **.********

65. spacer 3.4|1093794|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to AY526909 (Bordetella phage BIP-1, complete genome) position: , mismatch: 9, identity: 0.719

----gaatatcgggtgccagcctggacgctggccga	CRISPR spacer
tccacgat----ggtgccagccttgatgctggccgt	Protospacer
     .**    *********** **.********

66. spacer 3.6|1093916|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019604 (Croceicoccus marinus strain E4A9 plasmid pCME4A9II, complete sequence) position: , mismatch: 9, identity: 0.719

gaatatcgggtgccagcctggacgctggccga	CRISPR spacer
caacatcgggtggcagcctggacgtgtcgcgc	Protospacer
 **.******** ***********.    **

67. spacer 3.6|1093916|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025432 (Paracoccus zhejiangensis strain J6 plasmid pPZ02, complete sequence) position: , mismatch: 9, identity: 0.719

gaatatcgggtgccagcctggacgctggccga	CRISPR spacer
caaaccggggtgccagcctcgatgctggccat	Protospacer
 **  . ************ **.*******.

68. spacer 3.6|1093916|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to AY526908 (Bordetella phage BMP-1, complete genome) position: , mismatch: 9, identity: 0.719

----gaatatcgggtgccagcctggacgctggccga	CRISPR spacer
tccacgat----ggtgccagccttgatgctggccgt	Protospacer
     .**    *********** **.********

69. spacer 3.6|1093916|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NC_005357 (Bordetella phage BPP-1, complete genome) position: , mismatch: 9, identity: 0.719

----gaatatcgggtgccagcctggacgctggccga	CRISPR spacer
tccacgat----ggtgccagccttgatgctggccgt	Protospacer
     .**    *********** **.********

70. spacer 3.6|1093916|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to AY526909 (Bordetella phage BIP-1, complete genome) position: , mismatch: 9, identity: 0.719

----gaatatcgggtgccagcctggacgctggccga	CRISPR spacer
tccacgat----ggtgccagccttgatgctggccgt	Protospacer
     .**    *********** **.********

71. spacer 3.11|1094222|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to JN698994 (Mycobacterium phage DS6A, complete genome) position: , mismatch: 9, identity: 0.719

acgaaaatcgccgccggtgtcctcgctgatca	CRISPR spacer
cccgtagccgccgccggtggcctcgctggtcc	Protospacer
 * . *..*********** ********.**

72. spacer 3.15|1094466|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP044425 (Paracoccus pantotrophus strain DSM 2944 plasmid pPAN2, complete sequence) position: , mismatch: 9, identity: 0.719

------gcaatttgttgtccgcgatccggtacgcgcgt	CRISPR spacer
cgcggggc------ttggccgcgatccggtccgcgcga	Protospacer
      **      *** ************ ******

73. spacer 2.4|1067804|32|NZ_CP046000|CRISPRCasFinder,CRT matches to NZ_CP012383 (Streptomyces ambofaciens ATCC 23877 plasmid pSAM1, complete sequence) position: , mismatch: 10, identity: 0.688

gacgccgccgccgcgaagccgtttccgatgtt	CRISPR spacer
ttgcccgccgcggcgaagccgcttccgtcctc	Protospacer
    ******* *********.***** . *.

74. spacer 3.4|1093794|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025433 (Paracoccus zhejiangensis strain J6 plasmid pPZ03, complete sequence) position: , mismatch: 10, identity: 0.688

gaatatcgggtgccagcctggacgctggccga	CRISPR spacer
cagaccggggtgccagcctcgatgctggccat	Protospacer
 *.  . ************ **.*******.

75. spacer 3.6|1093916|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025433 (Paracoccus zhejiangensis strain J6 plasmid pPZ03, complete sequence) position: , mismatch: 10, identity: 0.688

gaatatcgggtgccagcctggacgctggccga	CRISPR spacer
cagaccggggtgccagcctcgatgctggccat	Protospacer
 *.  . ************ **.*******.

76. spacer 3.11|1094222|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NC_005241 (Cupriavidus necator H16 megaplasmid pHG1, complete sequence) position: , mismatch: 10, identity: 0.688

acgaaaatcgccgccggtgtcctcgctgatca	CRISPR spacer
ctacacgctgccgccggtggccgcgctgatca	Protospacer
 .. * ...********** ** *********

77. spacer 3.11|1094222|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039289 (Cupriavidus necator H16 plasmid pHG1, complete sequence) position: , mismatch: 10, identity: 0.688

acgaaaatcgccgccggtgtcctcgctgatca	CRISPR spacer
ctacacgctgccgccggtggccgcgctgatca	Protospacer
 .. * ...********** ** *********

78. spacer 3.11|1094222|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NC_030916 (Tsukamurella phage TPA4, complete genome) position: , mismatch: 10, identity: 0.688

acgaaaatcgccgccggtgtcctcgctgatca	CRISPR spacer
gatcaggccgacgccggtgtcctcgccgatcg	Protospacer
.   *...** ***************.****.

79. spacer 3.11|1094222|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to AB276040 (Ralstonia phage RSA1 DNA, complete genome) position: , mismatch: 10, identity: 0.688

acgaaaatcgccgccggtgtcctcgctgatca	CRISPR spacer
gacatgggcgccggcggtgtcctggctgatcg	Protospacer
.  * .. ***** ********* *******.

80. spacer 3.11|1094222|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NC_009382 (Ralstonia phage phiRSA1, complete genome) position: , mismatch: 10, identity: 0.688

acgaaaatcgccgccggtgtcctcgctgatca	CRISPR spacer
gacatgggcgccggcggtgtcctggctgatcg	Protospacer
.  * .. ***** ********* *******.

81. spacer 3.12|1094283|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to LN997844 (Streptomyces reticuli genome assembly TUE45, plasmid : III) position: , mismatch: 10, identity: 0.688

gactcaaccgcgcttcccggcctcaccactgc	CRISPR spacer
tgcgacaccgcgcttcccgggcgcaccacgca	Protospacer
 .*   ************** * ******

82. spacer 3.11|1094222|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NC_007974 (Cupriavidus metallidurans CH34 megaplasmid, complete sequence) position: , mismatch: 11, identity: 0.656

acgaaaatcgccgccggtgtcctcgctgatca	CRISPR spacer
gtactcgctgccgccggtggccgcgctgatca	Protospacer
...   ...********** ** *********

83. spacer 3.11|1094222|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017947 (Bosea sp. Tri-49 plasmid unnamed1, complete sequence) position: , mismatch: 11, identity: 0.656

acgaaaatcgccgccggtgtcctcgctgatca	CRISPR spacer
ctcgcgccagcggccggggtcctcgctgatca	Protospacer
 . . . . ** ***** **************

84. spacer 3.11|1094222|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046333 (Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3) position: , mismatch: 11, identity: 0.656

acgaaaatcgccgccggtgtcctcgctgatca	CRISPR spacer
gtactcgctgccgccggtggccgcgctgatca	Protospacer
...   ...********** ** *********

85. spacer 3.11|1094222|32|NZ_CP046000|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP033582 (Streptomyces sp. ADI95-16 plasmid pADI95-16a, complete sequence) position: , mismatch: 11, identity: 0.656

acgaaaatcgccgccggtgtcctcgctgatca	CRISPR spacer
cgtctgatcggcgccgatgtcctcgctgacgg	Protospacer
     .**** *****.************. .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

235334 : 285736

uncultured_Caudovirales_phage(23.08%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085948316.1\|235334_236608_-\|transposase	IS3 family transposase	Q9ZXG3	Shigella_phage	2.8e-170	95.7
WP_000100276.1\|236767_237769_-	permease	NA	NA	NA	NA
WP_001175589.1\|237875_238172_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000065786.1\|238305_238731_-	arsenate reductase (glutaredoxin)	A0A2H4J8T1	uncultured_Caudovirales_phage	2.5e-51	70.7
WP_000922639.1\|238743_240033_-	arsenite/antimonite:H(+) antiporter ArsB	A0A2H4J144	uncultured_Caudovirales_phage	4.6e-173	73.5
WP_000008957.1\|240086_240440_-	arsenical resistance operon transcriptional regulator ArsR	A0A2H4J145	uncultured_Caudovirales_phage	9.7e-25	50.9
WP_001295215.1\|241179_241263_+	hypothetical protein	NA	NA	NA	NA
WP_000160808.1\|241316_242669_-	glutathione-disulfide reductase	NA	NA	NA	NA
WP_000954225.1\|242740_243583_-	23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ	NA	NA	NA	NA
WP_001295214.1\|243785_245828_+	oligopeptidase A	A0A1V0SD92	Indivirus	3.4e-45	22.9
WP_000686627.1\|245835_246588_+	16S rRNA (guanine(1516)-N(2))-methyltransferase RsmJ	NA	NA	NA	NA
WP_001098652.1\|246636_248106_-	dipeptide/tripeptide permease DtpB	NA	NA	NA	NA
WP_000323571.1\|248423_248858_-	universal stress protein UspA	NA	NA	NA	NA
WP_000626187.1\|249248_249584_+	universal stress protein UspB	NA	NA	NA	NA
WP_000902780.1\|249654_251154_-	inorganic phosphate transporter PitA	NA	NA	NA	NA
WP_025653019.1\|251384_252587_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_000090707.1\|252729_253572_+\|transposase	transposase	NA	NA	NA	NA
WP_000351437.1\|253558_255682_+\|transposase	transposase	NA	NA	NA	NA
WP_001049180.1\|255681_257130_+	ATP-binding protein	NA	NA	NA	NA
WP_001324699.1\|257170_258727_+\|transposase	transposase	NA	NA	NA	NA
WP_000262423.1\|258738_259665_+	hypothetical protein	NA	NA	NA	NA
WP_001097216.1\|260017_260317_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_047649489.1\|261223_262204_-\|transposase	IS5-like element ISKpn26 family transposase	A0A077SK28	Escherichia_phage	3.4e-184	98.8
WP_154139469.1\|262257_263907_+	AAA family ATPase	NA	NA	NA	NA
WP_000647571.1\|264075_264426_-	DUF305 domain-containing protein	A0A218MND9	uncultured_virus	8.1e-16	61.4
WP_000790485.1\|264573_265005_-	silver-binding protein SilE	NA	NA	NA	NA
WP_000555736.1\|265249_266731_-	copper/silver sensor histidine kinase SilS	W8CYF6	Bacillus_phage	1.8e-27	30.1
WP_000697968.1\|266723_267404_-	copper/silver response regulator transcription factor SilR	W8CYM9	Bacillus_phage	2.7e-31	36.0
WP_000475507.1\|267593_268979_+	Cu(+)/Ag(+) efflux RND transporter outer membrane channel SilC	NA	NA	NA	NA
WP_001246155.1\|269006_269360_+	cation efflux system protein CusF	NA	NA	NA	NA
WP_001381488.1\|269473_270766_+	Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB	NA	NA	NA	NA
WP_020219104.1\|270776_273923_+	Cu(+)/Ag(+) efflux RND transporter permease subunit SilA	NA	NA	NA	NA
WP_000758229.1\|274009_274450_+	hypothetical protein	NA	NA	NA	NA
WP_001398208.1\|274547_277025_+	Ag(+)-translocating P-type ATPase SilP	A0A218MNH6	uncultured_virus	2.9e-83	35.4
WP_000843494.1\|277065_277263_+	DUF2933 domain-containing protein	NA	NA	NA	NA
WP_000287501.1\|277296_278034_-	peptidase	A8ATH6	Listeria_phage	1.0e-12	41.0
WP_001023257.1\|278322_278772_-	copper resistance protein	NA	NA	NA	NA
WP_000925240.1\|279006_280824_+	multicopper oxidase PcoA	NA	NA	NA	NA
WP_001242438.1\|280823_281720_+	copper resistance outer membrane transporter PcoB	NA	NA	NA	NA
WP_020219105.1\|281759_282140_+	copper resistance system metallochaperone PcoC	NA	NA	NA	NA
WP_000998778.1\|282144_283074_+	copper resistance inner membrane protein PcoD	NA	NA	NA	NA
WP_001188930.1\|283128_283809_+	copper response regulator transcription factor PcoR	W8CYM9	Bacillus_phage	8.7e-30	34.4
WP_085948178.1\|284523_285736_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7

DBSCAN-SWA_2

1110943 : 1122983

Escherichia_phage(62.5%)

integrase

attL 1102066:1102080|attR 1131831:1131845

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1102066:1102080	attL	NA	NA	NA	NA
WP_001278994.1\|1110943_1111582_-	aldolase	A0A077SK32	Escherichia_phage	1.4e-82	75.0
WP_000590385.1\|1111578_1112841_-	four-carbon acid sugar kinase family protein	A0A077SLJ7	Escherichia_phage	3.7e-135	61.4
WP_000847985.1\|1112837_1113746_-	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	3.0e-118	76.9
WP_001297141.1\|1113941_1114709_+	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	3.3e-70	56.7
WP_001141325.1\|1114759_1115416_-	protein-serine/threonine phosphatase	A0A222YWF0	Escherichia_phage	1.6e-49	46.3
WP_001696757.1\|1115521_1118089_-	DNA mismatch repair protein MutS	E3T5Q7	Cafeteria_roenbergensis_virus	1.0e-30	20.6
WP_000858985.1\|1118248_1119709_+\|integrase	tyrosine-type recombinase/integrase	A0A0R6PGY7	Moraxella_phage	5.4e-21	26.2
WP_001696754.1\|1119705_1120968_+	RNA-directed DNA polymerase	NA	NA	NA	NA
WP_001696753.1\|1120964_1122983_+	RNA-directed DNA polymerase	A0A0H4TEY7	Erysipelothrix_phage	2.0e-29	25.9
1131831:1131845	attR	NA	NA	NA	NA

DBSCAN-SWA_3

1719580 : 1791483

Enterobacteria_phage(41.18%)

transposase,tRNA,integrase

attL 1717219:1717236|attR 1781503:1781520

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1717219:1717236	attL	NA	NA	NA	NA
WP_047649489.1\|1719580_1720561_-\|transposase	IS5-like element ISKpn26 family transposase	A0A077SK28	Escherichia_phage	3.4e-184	98.8
WP_000097369.1\|1720986_1722702_-	D-lactate dehydrogenase	NA	NA	NA	NA
WP_000871517.1\|1722897_1725195_+	beta-glucosidase BglX	NA	NA	NA	NA
WP_001130306.1\|1725405_1726323_+	glycine betaine ABC transporter substrate-binding protein OsmF	NA	NA	NA	NA
WP_025649220.1\|1726329_1727487_+	glycine betaine ABC transporter permease YehY	NA	NA	NA	NA
WP_000569329.1\|1727479_1728406_+	glycine betaine ABC transporter ATP binding protein YehX	G3M9Y6	Bacillus_virus	2.8e-23	30.8
WP_000783120.1\|1728410_1729142_+	glycine betaine ABC transporter permease YehW	NA	NA	NA	NA
WP_001216961.1\|1729122_1729230_-	protein YohO	NA	NA	NA	NA
WP_001240401.1\|1729289_1730021_-	HTH-type transcriptional regulator MlrA	Q9EYF2	Enterobacteria_phage	9.7e-112	99.5
WP_001295431.1\|1730242_1731928_+	two-component regulatory system sensor histidine kinase BtsS	Q9EYF3	Enterobacteria_phage	2.5e-304	99.6
WP_001326002.1\|1731924_1732644_+	two-component system response regulator BtsR	NA	NA	NA	NA
WP_000950409.1\|1732690_1733161_+	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	5.2e-82	100.0
WP_001378226.1\|1733200_1733662_-	YehR family lipoprotein	Q9EYF5	Enterobacteria_phage	5.4e-76	99.3
WP_001326004.1\|1733786_1735787_-	hypothetical protein	Q9EYF6	Enterobacteria_phage	0.0e+00	95.8
WP_001292774.1\|1735783_1736920_-	VWA domain-containing protein	Q9EYF7	Enterobacteria_phage	1.1e-162	97.7
WP_001294366.1\|1736912_1739192_-	hypothetical protein	NA	NA	NA	NA
WP_000074859.1\|1739202_1740291_-	MoxR family ATPase	NA	NA	NA	NA
WP_000636926.1\|1741473_1741794_-	hypothetical protein	NA	NA	NA	NA
WP_000356790.1\|1741854_1745487_-	DUF4132 domain-containing protein	NA	NA	NA	NA
WP_001295427.1\|1749431_1751465_-\|tRNA	methionine--tRNA ligase	A0A1V0SDF2	Indivirus	1.8e-54	27.6
WP_001005448.1\|1751596_1752706_+	iron-sulfur cluster carrier protein ApbC	NA	NA	NA	NA
WP_001324851.1\|1752968_1753250_+	YehE family protein	NA	NA	NA	NA
WP_000830468.1\|1753542_1754085_+	fimbrial protein	NA	NA	NA	NA
WP_000677395.1\|1754165_1754840_+	fimbria/pilus periplasmic chaperone	NA	NA	NA	NA
WP_085948316.1\|1757148_1758421_+\|transposase	IS3 family transposase	Q9ZXG3	Shigella_phage	2.8e-170	95.7
WP_000405707.1\|1758687_1759722_+	putative fimbrial-like adhesin protein	NA	NA	NA	NA
WP_000153067.1\|1759803_1760142_-	Ni(II)/Co(II) efflux transporter accessory subunit RcnB	NA	NA	NA	NA
WP_000134569.1\|1760360_1761185_-	nickel/cobalt efflux protein RcnA	NA	NA	NA	NA
WP_000019944.1\|1761305_1761578_+	Ni(II)/Co(II)-binding transcriptional repressor RcnR	NA	NA	NA	NA
WP_001118621.1\|1762991_1763915_+\|transposase	IS5 family transposase	Q1MVF0	Enterobacteria_phage	8.4e-177	100.0
WP_025653401.1\|1764370_1765816_+	ATP-binding protein	E5E3R2	Burkholderia_phage	3.7e-06	27.6
WP_025653400.1\|1766135_1767155_-	hypothetical protein	NA	NA	NA	NA
WP_025653399.1\|1767167_1767539_-	hypothetical protein	NA	NA	NA	NA
WP_007666098.1\|1769560_1769986_+	hypothetical protein	NA	NA	NA	NA
WP_025653397.1\|1770263_1770452_+	hypothetical protein	NA	NA	NA	NA
WP_001011965.1\|1771576_1772143_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_001058091.1\|1773106_1773289_+	hypothetical protein	NA	NA	NA	NA
WP_001195605.1\|1773626_1774415_+	hydroxyethylthiazole kinase	NA	NA	NA	NA
WP_000822274.1\|1774411_1775212_+	bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase	NA	NA	NA	NA
WP_001297420.1\|1775276_1776095_+	glycosyl hydrolase 25 family protein	D0R7H8	Paenibacillus_phage	2.3e-24	38.5
WP_000434038.1\|1776146_1776893_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_000011957.1\|1776866_1777832_-	sugar kinase	NA	NA	NA	NA
WP_000846217.1\|1777828_1778833_-	ADP-ribosylglycohydrolase family protein	A0A1S6UB21	Serratia_phage	7.5e-14	29.4
WP_000858498.1\|1778829_1780107_-	MFS transporter	NA	NA	NA	NA
WP_000129551.1\|1780363_1781416_+	class I fructose-bisphosphate aldolase	NA	NA	NA	NA
WP_025650478.1\|1781725_1782580_+	tagatose-bisphosphate aldolase subunit GatY	NA	NA	NA	NA
1781503:1781520	attR	NA	NA	NA	NA
WP_000853876.1\|1782608_1783871_+	tagatose-bisphosphate aldolase subunit GatZ	NA	NA	NA	NA
WP_000182914.1\|1783880_1784333_+	PTS galactitol transporter subunit IIA	NA	NA	NA	NA
WP_000823272.1\|1784363_1784648_+	PTS galactitol transporter subunit IIB	NA	NA	NA	NA
WP_000490679.1\|1784651_1786007_+	galactitol permease IIC component	NA	NA	NA	NA
WP_000844200.1\|1786054_1787095_+	galactitol-1-phosphate 5-dehydrogenase	NA	NA	NA	NA
WP_000178552.1\|1787194_1787974_+	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
WP_000807362.1\|1788055_1788955_-	lipid kinase YegS	A0A1V0SBJ0	Catovirus	1.3e-12	29.0
WP_000019448.1\|1789302_1790283_-\|transposase	IS5-like element ISKpn26 family transposase	A0A077SK28	Escherichia_phage	8.9e-185	99.1
WP_047649489.1\|1790502_1791483_-\|transposase	IS5-like element ISKpn26 family transposase	A0A077SK28	Escherichia_phage	3.4e-184	98.8

DBSCAN-SWA_4

3004040 : 3091886

Salmonella_phage(57.63%)

integrase,protease,tRNA,head,capsid,lysis,tail,portal,terminase,plate

attL 2997001:2997016|attR 3094457:3094472

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2997001:2997016	attL	NA	NA	NA	NA
WP_000886683.1\|3004040_3005333_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	1.5e-94	48.2
WP_000067740.1\|3005423_3006767_-	replication-associated recombination protein A	G3MBE0	Bacillus_virus	3.6e-80	40.6
WP_001295343.1\|3006777_3007389_-	outer membrane lipoprotein chaperone LolA	NA	NA	NA	NA
WP_000077064.1\|3007543_3011650_-	DNA translocase FtsK	A0A218M9A2	Mycobacterium_phage	1.2e-86	48.7
WP_000228473.1\|3011784_3012279_-	leucine-responsive transcriptional regulator Lrp	NA	NA	NA	NA
WP_000537418.1\|3012823_3013789_+	thioredoxin-disulfide reductase	A0A2I2L5E1	Orpheovirus	8.5e-63	44.6
WP_001043615.1\|3013911_3015678_+	cysteine/glutathione ABC transporter permease/ATP-binding protein CydD	W8CYL7	Bacillus_phage	5.4e-23	24.3
WP_001202189.1\|3015678_3017400_+	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	W8CYL7	Bacillus_phage	2.9e-21	25.2
WP_001241678.1\|3017441_3018146_+\|tRNA	leucyl/phenylalanyl-tRNA--protein transferase	NA	NA	NA	NA
WP_001040187.1\|3018430_3018649_+	translation initiation factor IF-1	NA	NA	NA	NA
WP_000934041.1\|3019332_3021609_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	1.9e-166	42.5
WP_000520781.1\|3021639_3021960_-\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	1.6e-13	44.4
WP_000410785.1\|3022282_3022507_+	cold shock-like protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	2.3e-16	61.2
WP_000188180.1\|3022579_3024526_-	macrolide ABC transporter ATP-binding protein/permease MacB	G9BWD6	Planktothrix_phage	1.1e-37	40.1
WP_000746460.1\|3024522_3025638_-	macrolide transporter subunit MacA	NA	NA	NA	NA
WP_001355621.1\|3025788_3026745_+	DUF535 domain-containing protein	NA	NA	NA	NA
WP_000599806.1\|3026741_3028400_-	ATP-dependent endonuclease	NA	NA	NA	NA
WP_001297311.1\|3028825_3029521_+	aquaporin Z	NA	NA	NA	NA
WP_000491142.1\|3030015_3030915_+	L-lysine exporter LysO	NA	NA	NA	NA
WP_000458817.1\|3031058_3032711_+	hydroxylamine reductase	NA	NA	NA	NA
WP_000178677.1\|3032722_3033691_+	NADH oxidoreductase	NA	NA	NA	NA
WP_000815351.1\|3033823_3035542_+	ubiquinone-dependent pyruvate dehydrogenase	A0A0P0YLY7	Yellowstone_lake_phycodnavirus	6.8e-31	24.1
WP_000566372.1\|3035578_3036580_+	low-specificity L-threonine aldolase	NA	NA	NA	NA
WP_001136554.1\|3036590_3038021_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_001338420.1\|3038119_3039133_+	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_001255144.1\|3039129_3039960_-	N-acetylmuramoyl-L-alanine amidase	A0A1B0UZW5	Roseobacter_phage	5.7e-07	30.0
WP_001160737.1\|3039956_3040280_-	heavy metal-binding domain-containing protein	NA	NA	NA	NA
WP_001270740.1\|3040405_3040921_+	lipoprotein	NA	NA	NA	NA
WP_000027205.1\|3041138_3041867_+	arginine ABC transporter ATP-binding protein ArtP	G9BWD6	Planktothrix_phage	6.0e-29	36.7
WP_000756569.1\|3041884_3042616_+	arginine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_001001691.1\|3042622_3043339_+	arginine ABC transporter permease ArtQ	NA	NA	NA	NA
WP_000464491.1\|3043338_3044007_+	arginine ABC transporter permease ArtM	NA	NA	NA	NA
WP_001295905.1\|3044298_3045030_+	arginine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_001149732.1\|3045204_3046332_-	23S rRNA (uracil(747)-C(5))-methyltransferase RlmC	A0A1X9I6F4	Streptococcus_phage	3.5e-28	27.6
WP_000389260.1\|3046372_3046861_-	YbjO family protein	NA	NA	NA	NA
WP_001061657.1\|3046920_3047766_-	putrescine ABC transporter permease PotI	NA	NA	NA	NA
WP_001093858.1\|3047762_3048716_-	putrescine ABC transporter permease PotH	NA	NA	NA	NA
WP_000996018.1\|3048725_3049859_-	putrescine ABC transporter ATP-binding subunit PotG	G3M9Y6	Bacillus_virus	1.4e-29	34.0
WP_000126084.1\|3049953_3051066_-	spermidine/putrescine ABC transporter substrate-binding protein PotF	NA	NA	NA	NA
WP_000203025.1\|3051416_3051893_-	YbjN domain-containing protein	NA	NA	NA	NA
WP_000684321.1\|3051980_3052883_-	30S ribosomal protein S6--L-glutamate ligase	I3ULC9	Synechococcus_phage	2.6e-37	34.4
WP_025649937.1\|3052943_3053666_-	nitroreductase NfsA	NA	NA	NA	NA
WP_001201560.1\|3053649_3053937_-	DUF1418 family protein	NA	NA	NA	NA
WP_001195240.1\|3054096_3054354_+	GrxA family glutaredoxin	A0A2I7SAE2	Vibrio_phage	8.6e-23	61.9
WP_000681108.1\|3054383_3054761_-	hypothetical protein	NA	NA	NA	NA
WP_001024876.1\|3055030_3056716_+	transporter	NA	NA	NA	NA
WP_000972391.1\|3056951_3057170_-	transcriptional activator Ogr/delta	Q53ZE7	Salmonella_virus	7.5e-20	69.0
WP_033551100.1\|3057260_3058361_-	phage late control D family protein	A0A1S6KZZ5	Salmonella_phage	1.1e-175	87.7
WP_000980413.1\|3058357_3058843_-\|tail	phage tail protein	E5G6Q2	Salmonella_phage	6.3e-67	80.6
WP_033551099.1\|3058839_3061917_-\|tail	phage tail tape measure protein	E5G6Q1	Salmonella_phage	0.0e+00	62.9
WP_000763311.1\|3061909_3062029_-\|tail	GpE family phage tail protein	E5G6Q0	Salmonella_phage	2.8e-13	87.2
WP_001281009.1\|3062043_3062346_-\|tail	phage tail assembly protein	A0A1S6KZZ9	Salmonella_phage	5.3e-40	89.0
WP_001207660.1\|3062400_3062916_-\|tail	phage major tail tube protein	A0A1S6L002	Salmonella_phage	2.1e-89	95.3
WP_033551098.1\|3062925_3064098_-\|tail	phage tail sheath protein	A0A1S6KZY7	Salmonella_phage	1.1e-202	90.0
WP_029697337.1\|3064249_3064807_-	recombinase family protein	A0A1S6L009	Salmonella_phage	1.4e-86	84.8
WP_077898376.1\|3064836_3065346_+\|tail	tail fiber protein	Q9MCR6	Enterobacteria_phage	3.0e-51	66.1
WP_154139600.1\|3065345_3065948_+\|tail	tail fiber assembly protein	M1SV83	Escherichia_phage	7.3e-97	89.0
WP_001463953.1\|3065919_3066363_-\|tail	caudovirales tail fiber assembly family protein	A0A0F7LDZ0	Escherichia_phage	2.4e-36	49.7
WP_089632067.1\|3066365_3067868_-\|tail	phage tail protein	M1TAS6	Escherichia_phage	4.7e-153	78.7
WP_001086836.1\|3067864_3068470_-\|tail	phage tail protein I	A0A1S6L000	Salmonella_phage	1.5e-110	92.5
WP_154139542.1\|3068462_3069371_-\|plate	baseplate assembly protein	A0A1S6KZY6	Salmonella_phage	5.0e-142	90.1
WP_000177590.1\|3069357_3069717_-\|plate	baseplate assembly protein	A0A1S6KZZ4	Salmonella_phage	9.5e-52	86.6
WP_089588518.1\|3069713_3070292_-\|plate	phage baseplate assembly protein V	A0A1S6KZX7	Salmonella_phage	1.6e-93	86.5
WP_000829157.1\|3070360_3070807_-	phage virion morphogenesis protein	A0A1S6L001	Salmonella_phage	1.9e-62	84.9
WP_001039945.1\|3070799_3071231_-\|tail	phage tail protein	E5G6N3	Salmonella_phage	4.4e-72	94.4
WP_154139544.1\|3071326_3071755_-\|lysis	LysB family phage lysis regulatory protein	E5G6N2	Salmonella_phage	6.2e-58	87.9
WP_001069904.1\|3071751_3072267_-	lysozyme	E5G6N1	Salmonella_phage	7.4e-90	93.0
WP_000171568.1\|3072247_3072463_-	hypothetical protein	E5G6N0	Salmonella_phage	1.8e-26	80.3
WP_000868175.1\|3072466_3072670_-\|tail	tail protein X	E5G6M9	Salmonella_phage	1.4e-31	92.5
WP_000673520.1\|3072669_3073134_-\|head	head completion/stabilization protein	A0A1S6KZW8	Salmonella_phage	4.2e-76	89.0
WP_000059193.1\|3073229_3073880_-\|terminase	terminase endonuclease subunit	E5G6M7	Salmonella_phage	4.3e-111	95.4
WP_000742511.1\|3073883_3074942_-\|capsid	phage major capsid protein, P2 family	E5G6M6	Salmonella_phage	2.9e-181	93.4
WP_001554837.1\|3074958_3075792_-\|capsid	GPO family capsid scaffolding protein	A0A1S6KZW9	Salmonella_phage	5.3e-122	91.7
WP_089588519.1\|3075934_3077701_+\|terminase	terminase ATPase subunit family protein	A0A1S6KZW3	Salmonella_phage	0.0e+00	99.5
WP_089588520.1\|3077700_3078729_+\|portal	phage portal protein	A0A1S6KZW5	Salmonella_phage	2.9e-170	88.5
WP_089588521.1\|3078760_3079444_-	RelA/SpoT domain-containing protein	NA	NA	NA	NA
WP_089588522.1\|3079440_3080544_-	AAA family ATPase	Q7M293	Enterobacteria_phage	5.0e-19	26.2
WP_028985770.1\|3081044_3082088_+	hypothetical protein	NA	NA	NA	NA
WP_029364119.1\|3082084_3083944_+	ATP-binding protein	NA	NA	NA	NA
WP_023486382.1\|3084088_3084322_-	DinI family protein	E5G6M1	Salmonella_phage	8.0e-36	98.7
WP_001154431.1\|3084332_3084521_-	hypothetical protein	E5G6M0	Salmonella_phage	1.6e-26	96.8
WP_047649414.1\|3084673_3087088_-	replication endonuclease	E5G6L9	Salmonella_phage	0.0e+00	97.1
WP_000104157.1\|3087084_3087942_-	DNA adenine methylase	E5G6L8	Salmonella_phage	4.1e-162	98.2
WP_000752613.1\|3087938_3088166_-	TraR/DksA family transcriptional regulator	E5G6L7	Salmonella_phage	2.7e-36	100.0
WP_097494783.1\|3088165_3088399_-	DUF2732 family protein	E5G6L6	Salmonella_phage	1.2e-31	96.1
WP_001352070.1\|3088466_3088808_-	hypothetical protein	E5G6L5	Salmonella_phage	4.3e-54	96.5
WP_000956182.1\|3088771_3088972_-	DUF2724 domain-containing protein	E5G6L4	Salmonella_phage	7.1e-33	98.5
WP_000460891.1\|3088979_3089489_-	phage regulatory CII family protein	E5G6L3	Salmonella_phage	1.3e-86	98.2
WP_001247707.1\|3089521_3089743_-	hypothetical protein	NA	NA	NA	NA
WP_001047320.1\|3089868_3090438_+	phage repressor protein CI	A0A1S6KZZ7	Salmonella_phage	2.9e-39	43.9
WP_001513672.1\|3090453_3090645_+	hypothetical protein	A0A0R6PIH8	Moraxella_phage	6.8e-09	65.9
WP_000290937.1\|3090833_3091886_+\|integrase	tyrosine-type recombinase/integrase	A0A218M4I3	Erwinia_phage	3.6e-107	57.3
3094457:3094472	attR	NA	NA	NA	NA

DBSCAN-SWA_5

3385581 : 3404840

Escherichia_phage(38.46%)

transposase,protease,integrase,tail

attL 3396105:3396164|attR 3401330:3402636

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047649489.1\|3385581_3386562_-\|transposase	IS5-like element ISKpn26 family transposase	A0A077SK28	Escherichia_phage	3.4e-184	98.8
WP_000019440.1\|3386780_3387761_-\|transposase	IS5-like element ISKpn26 family transposase	A0A077SK28	Escherichia_phage	6.8e-185	99.1
WP_106423173.1\|3387795_3388212_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_001201857.1\|3388725_3389679_+\|protease	omptin family outer membrane protease OmpT	NA	NA	NA	NA
WP_000386784.1\|3389928_3390678_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_000239874.1\|3391537_3392206_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_120795384.1\|3392571_3392685_+	Rac prophage; protein YnaM	A0A1C9IHU6	Salmonella_phage	8.4e-07	80.6
WP_000836768.1\|3392753_3392987_+	cold shock protein YdfK	A0A192Y6D5	Salmonella_phage	1.1e-32	88.3
WP_000078177.1\|3393303_3393894_+	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	1.6e-24	38.8
WP_154139554.1\|3393991_3394558_-\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	8.6e-100	93.7
3396105:3396164	attL	NA	NA	NA	NA
WP_085948178.1\|3396155_3397368_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_000738421.1\|3397913_3398207_+	increased serum survival lipoprotein Iss	K7PL54	Enterobacteria_phage	5.9e-44	90.7
WP_085948316.1\|3398621_3399895_-\|transposase	IS3 family transposase	Q9ZXG3	Shigella_phage	2.8e-170	95.7
WP_154139556.1\|3399925_3400072_-	hypothetical protein	NA	NA	NA	NA
WP_071790554.1\|3400115_3400487_+	helix-turn-helix domain-containing protein	M1FJ59	Enterobacteria_phage	3.0e-45	80.2
WP_154139558.1\|3400342_3401329_+\|integrase	tyrosine-type recombinase/integrase	A0A088CD23	Shigella_phage	9.0e-169	86.9
WP_085948178.1\|3401380_3402593_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_000019440.1\|3403859_3404840_-\|transposase	IS5-like element ISKpn26 family transposase	A0A077SK28	Escherichia_phage	6.8e-185	99.1
3401330:3402636	attR	NA	NA	NA	NA

DBSCAN-SWA_6

3646558 : 3730602

Shigella_phage(45.31%)

integrase,protease,head,capsid,transposase,tail,holin,portal,terminase,plate

attL 3666164:3666180|attR 3728048:3728064

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000131044.1\|3646558_3648592_-\|holin	choline BCCT transporter BetT	A0A2I7QNT1	Vibrio_phage	3.4e-21	27.4
WP_025649816.1\|3648720_3649308_+	transcriptional regulator BetI	NA	NA	NA	NA
WP_000089092.1\|3649321_3650794_+	betaine-aldehyde dehydrogenase	NA	NA	NA	NA
WP_001159102.1\|3650807_3652478_+\|holin	choline dehydrogenase	A0A1V0S9M4	Catovirus	4.7e-61	31.2
WP_001209105.1\|3652690_3653359_+	membrane protein	NA	NA	NA	NA
WP_000370401.1\|3653601_3654297_-	lactate utilization protein C	NA	NA	NA	NA
WP_000023907.1\|3654289_3655717_-	iron-sulfur cluster-binding protein	NA	NA	NA	NA
WP_001102119.1\|3655727_3656447_-	(Fe-S)-binding protein	NA	NA	NA	NA
WP_025649824.1\|3656973_3657828_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_154139573.1\|3658053_3659379_+	pyridine nucleotide-disulfide oxidoreductase	A0A2K5B2C5	Erysipelothrix_phage	2.5e-113	47.6
WP_000474077.1\|3659487_3659724_+	DUF1471 domain-containing protein	NA	NA	NA	NA
WP_001299021.1\|3659735_3660329_+	reactive chlorine species resistance protein RclC	NA	NA	NA	NA
WP_001299025.1\|3660488_3661358_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	9.3e-53	41.7
WP_000621018.1\|3661606_3662464_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_000092611.1\|3662584_3666838_-	intimin-like adhesin FdeC	NA	NA	NA	NA
3666164:3666180	attL	NA	NA	NA	NA
WP_000662258.1\|3667953_3668055_+	hypothetical protein	NA	NA	NA	NA
WP_000803999.1\|3668417_3668681_+	type B 50S ribosomal protein L31	NA	NA	NA	NA
WP_000866436.1\|3668680_3668821_+	50S ribosomal protein L36	NA	NA	NA	NA
WP_001147277.1\|3668855_3669083_-	hypothetical protein	NA	NA	NA	NA
WP_025649835.1\|3669905_3670448_+	ECP biosynthesis operon DNA-binding transcriptional regulator EcpR	NA	NA	NA	NA
WP_000730972.1\|3670522_3671110_+	common pilus major fimbrillin subunit EcpA	NA	NA	NA	NA
WP_000716398.1\|3671168_3671837_+	fimbrial chaperone EcpB	NA	NA	NA	NA
WP_001131077.1\|3671862_3674388_+	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_085948316.1\|3675137_3676411_-\|transposase	IS3 family transposase	Q9ZXG3	Shigella_phage	2.8e-170	95.7
WP_001305432.1\|3677325_3678036_+	hypothetical protein	NA	NA	NA	NA
WP_001303809.1\|3678348_3678678_+	YkgJ family cysteine cluster protein	NA	NA	NA	NA
WP_001019920.1\|3678925_3679540_-	YagU family protein	NA	NA	NA	NA
WP_000643333.1\|3680632_3681589_+	xanthine dehydrogenase family protein subunit M	NA	NA	NA	NA
WP_000667026.1\|3681585_3683784_+	xanthine dehydrogenase family protein molybdopterin-binding subunit	A0A0P0I429	Acinetobacter_phage	2.5e-38	25.8
WP_000121333.1\|3683793_3684750_+	molybdenum cofactor insertion chaperone PaoD	NA	NA	NA	NA
WP_001111349.1\|3684728_3685139_+	transcriptional regulator	NA	NA	NA	NA
WP_012602456.1\|3685957_3687172_+	type II restriction endonuclease	E5E3X4	Burkholderia_phage	7.9e-34	38.6
WP_001288444.1\|3687206_3688640_-	DNA cytosine methyltransferase	E5E3X6	Burkholderia_phage	4.1e-106	50.1
WP_000355481.1\|3689048_3689822_+	hypothetical protein	G9IA57	Pseudomonas_phage	1.9e-36	38.9
WP_021556504.1\|3689879_3690434_-	site-specific DNA recombinase	A0A1S6L009	Salmonella_phage	1.8e-86	87.3
WP_001115559.1\|3690463_3690955_+	hypothetical protein	F1BUP1	Erwinia_phage	4.8e-06	35.3
WP_086259928.1\|3690957_3691401_+\|tail	phage tail protein	A0A0F7LDZ0	Escherichia_phage	2.4e-36	49.7
WP_024234210.1\|3691372_3691975_-\|tail	tail fiber assembly protein	M1SV83	Escherichia_phage	1.9e-97	89.5
WP_089540311.1\|3691974_3692736_-\|tail	tail fiber protein	Q9MCR6	Enterobacteria_phage	2.6e-51	66.1
WP_000383548.1\|3692739_3693324_-	YmfQ family protein	O22003	Shigella_phage	1.1e-113	100.0
WP_032141738.1\|3693314_3694373_-\|plate	baseplate J/gp47 family protein	M1FQW3	Enterobacteria_phage	2.3e-199	98.3
WP_000424732.1\|3694359_3694785_-	hypothetical protein	U5P0R9	Shigella_phage	2.3e-81	100.0
WP_001259084.1\|3694784_3695333_-\|plate	phage baseplate assembly protein V	U5P081	Shigella_phage	5.1e-97	98.9
WP_000999511.1\|3695332_3696412_-\|plate	baseplate protein	U5P0H6	Shigella_phage	2.6e-206	99.7
WP_000219917.1\|3696408_3697737_-	DNA circularization protein	Q8SBG8	Shigella_phage	3.5e-245	98.6
WP_000734912.1\|3697847_3698294_+	hypothetical protein	NA	NA	NA	NA
WP_032201156.1\|3698325_3700158_-\|tail	phage tail tape measure protein	S5FM63	Shigella_phage	3.9e-303	98.5
WP_000661047.1\|3700299_3700569_-\|tail	phage tail assembly protein	S5FNR3	Shigella_phage	3.5e-43	100.0
WP_000090998.1\|3700568_3700925_-	hypothetical protein	U5P076	Shigella_phage	5.3e-63	100.0
WP_047664120.1\|3700924_3702421_-\|tail	tail sheath protein	M1FN90	Enterobacteria_phage	3.1e-274	99.6
WP_000497757.1\|3702404_3702575_-	DUF2635 domain-containing protein	Q8SBH3	Shigella_phage	2.7e-25	98.2
WP_047664123.1\|3702583_3703144_-	hypothetical protein	M1FQV7	Enterobacteria_phage	5.2e-105	98.9
WP_000213502.1\|3703140_3703647_-	hypothetical protein	M1FPE2	Enterobacteria_phage	1.7e-91	100.0
WP_000702398.1\|3703621_3704032_-\|head	phage head closure protein	M1FJ87	Enterobacteria_phage	3.1e-75	100.0
WP_000927710.1\|3704028_3704352_-\|head,tail	phage gp6-like head-tail connector protein	S5FKK6	Shigella_phage	5.1e-57	100.0
WP_072808084.1\|3704354_3704555_-	hypothetical protein	S5FNU1	Shigella_phage	1.3e-26	98.5
WP_000257507.1\|3704604_3705810_-\|capsid	phage major capsid protein	M1FPN2	Enterobacteria_phage	1.8e-224	100.0
WP_001193631.1\|3705824_3706475_-\|head,protease	HK97 family phage prohead protease	U5P4H2	Shigella_phage	2.5e-119	100.0
WP_000466255.1\|3706452_3707694_-\|portal	phage portal protein	U5P411	Shigella_phage	2.0e-242	99.8
WP_000605606.1\|3707693_3707876_-	hypothetical protein	S5FXQ9	Shigella_phage	1.7e-25	100.0
WP_122985710.1\|3707887_3709384_-\|terminase	terminase large subunit	U5P0Q5	Shigella_phage	1.5e-300	99.8
WP_000929173.1\|3709617_3710112_-\|terminase	phage terminase small subunit P27 family	Q8SBI1	Shigella_phage	1.3e-88	100.0
WP_001131133.1\|3710237_3710588_-	HNH endonuclease	Q8SBD7	Shigella_phage	1.4e-60	93.1
WP_053897783.1\|3710738_3711074_+	hypothetical protein	NA	NA	NA	NA
WP_000613842.1\|3711174_3711744_+	hypothetical protein	NA	NA	NA	NA
WP_122986267.1\|3711765_3712023_-	peptidase	Q8SBD8	Shigella_phage	3.7e-26	75.6
WP_001356320.1\|3711907_3712300_-	DUF2570 domain-containing protein	U5P0U9	Shigella_phage	9.3e-53	87.6
WP_001148538.1\|3712283_3712760_-	glycoside hydrolase family protein	S5FV07	Shigella_phage	2.4e-87	98.1
WP_001532222.1\|3712763_3713090_-\|holin	phage holin, lambda family	S5FM86	Shigella_phage	3.4e-56	98.1
WP_000799659.1\|3713166_3714219_-	site-specific DNA-methyltransferase	A5LH81	Enterobacteria_phage	6.8e-207	99.1
WP_000917730.1\|3714369_3714573_-	hypothetical protein	A0A291AWX6	Escherichia_phage	1.8e-31	98.5
WP_032252670.1\|3714973_3715837_+	NYN domain-containing protein	A4JWQ6	Burkholderia_virus	1.4e-40	41.0
WP_077908626.1\|3715849_3716215_-	antitermination protein Q	A5LH77	Enterobacteria_phage	6.4e-56	90.0
WP_001420253.1\|3716230_3717220_-	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	5.6e-195	99.7
WP_032305273.1\|3717227_3718025_-	KilA-N domain-containing protein	A0A0P0ZCS0	Stx2-converting_phage	1.5e-150	99.6
WP_000767113.1\|3718044_3718434_-	RusA family crossover junction endodeoxyribonuclease	A0A0P0ZD39	Stx2-converting_phage	7.1e-69	100.0
WP_000210152.1\|3718430_3718757_-	LexA family transcriptional regulator	A0A0N7KZF7	Stx2-converting_phage	1.3e-52	98.1
WP_000066917.1\|3718753_3719407_-	phage N-6-adenine-methyltransferase	A5LH72	Enterobacteria_phage	1.9e-127	99.5
WP_001619134.1\|3719406_3719901_-	PerC family transcriptional regulator	A0A291AWV6	Escherichia_phage	1.2e-86	98.1
WP_154139575.1\|3719897_3720839_-	GntR family transcriptional regulator	S5FM81	Shigella_phage	2.8e-143	99.4
WP_001250269.1\|3720828_3721008_-	DUF4222 domain-containing protein	S5M7S5	Escherichia_phage	7.8e-15	68.5
WP_154139602.1\|3721183_3721735_-	hypothetical protein	S5FXP0	Shigella_phage	2.9e-100	98.4
WP_000205494.1\|3721772_3721973_-	cell division protein	NA	NA	NA	NA
WP_000450735.1\|3722070_3722697_+	LexA family transcriptional regulator	K7PM82	Enterobacteria_phage	5.5e-47	48.8
WP_000549626.1\|3722944_3723151_+	hypothetical protein	NA	NA	NA	NA
WP_000016389.1\|3723122_3723557_-	hypothetical protein	U5P096	Shigella_phage	8.4e-79	100.0
WP_000008235.1\|3724101_3724638_+	5'-deoxynucleotidase	S5MW55	Escherichia_phage	8.2e-100	98.9
WP_001242749.1\|3724628_3724991_+	phage protein	U5P092	Shigella_phage	2.1e-67	100.0
WP_000206732.1\|3724990_3725296_+	hypothetical protein	U5P0J0	Shigella_phage	6.8e-51	100.0
WP_077873866.1\|3725211_3725646_+	helix-turn-helix domain-containing protein	U5P4J3	Shigella_phage	6.4e-79	100.0
WP_000051887.1\|3725522_3726686_+\|integrase	site-specific integrase	U5P434	Shigella_phage	2.4e-229	100.0
WP_000893255.1\|3726890_3728144_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	5.8e-96	47.2
3728048:3728064	attR	NA	NA	NA	NA
WP_001285288.1\|3728155_3729259_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.1e-61	40.4
WP_000749863.1\|3729546_3730602_+	phosphoporin PhoE	Q1MVN1	Enterobacteria_phage	9.1e-119	61.1

DBSCAN-SWA_7

3980791 : 4088691

106

Enterobacteria_phage(42.19%)

integrase,tRNA,head,capsid,lysis,transposase,tail,portal,terminase

attL 4076905:4076919|attR 4089869:4089883

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001286834.1\|3980791_3983608_-\|tRNA	isoleucine--tRNA ligase	A0A2K9L260	Tupanvirus	7.9e-77	26.1
WP_000767329.1\|3983650_3984592_-	bifunctional riboflavin kinase/FAD synthetase	NA	NA	NA	NA
WP_001295417.1\|3984599_3984818_-	DUF2575 domain-containing protein	NA	NA	NA	NA
WP_001274021.1\|3984920_3985184_+	30S ribosomal protein S20	NA	NA	NA	NA
WP_025653107.1\|3988678_3989296_+	hypothetical protein	NA	NA	NA	NA
WP_085948316.1\|3989326_3990599_+\|transposase	IS3 family transposase	Q9ZXG3	Shigella_phage	2.8e-170	95.7
WP_000062888.1\|3991012_3991918_-	transcriptional activator NhaR	NA	NA	NA	NA
WP_000681368.1\|3991977_3993144_-	Na+/H+ antiporter NhaA	A0A2H4J5W3	uncultured_Caudovirales_phage	9.2e-88	53.8
WP_000935262.1\|3993672_3993882_+	type I toxin-antitoxin system toxin MokC	A0A0P0ZAX5	Stx2-converting_phage	8.0e-19	73.9
WP_001118464.1\|3993985_3995116_-	molecular chaperone DnaJ	E3T4P7	Cafeteria_roenbergensis_virus	4.6e-28	34.6
WP_000516135.1\|3995204_3997121_-	molecular chaperone DnaK	A0A0N9QXN8	Chrysochromulina_ericina_virus	6.9e-149	51.1
WP_000843559.1\|3997497_3997902_+	DUF2541 family protein	NA	NA	NA	NA
WP_001102383.1\|3997927_3998641_+	acidic protein MsyB	NA	NA	NA	NA
WP_000528538.1\|3998789_3999356_+	acetate uptake transporter	NA	NA	NA	NA
WP_001094682.1\|3999390_3999978_-	molybdopterin adenylyltransferase	NA	NA	NA	NA
WP_000130185.1\|4000092_4001046_-	transaldolase	A0A127KNC6	Cyanophage	1.7e-10	31.5
WP_001112599.1\|4001324_4002755_+	sodium:alanine symporter family protein	NA	NA	NA	NA
WP_000906204.1\|4002824_4003601_+	peroxide stress protein YaaA	NA	NA	NA	NA
WP_000399648.1\|4003792_4004773_-\|transposase	IS110-like element IS621 family transposase	NA	NA	NA	NA
WP_000738721.1\|4005032_4005329_-	DUF2502 domain-containing protein	NA	NA	NA	NA
WP_000781063.1\|4005542_4006829_-	threonine synthase	NA	NA	NA	NA
WP_000241660.1\|4006829_4007762_-	homoserine kinase	NA	NA	NA	NA
WP_001264725.1\|4007763_4010226_-	bifunctional aspartate kinase/homoserine dehydrogenase I	NA	NA	NA	NA
WP_001386572.1\|4010306_4010372_-	thr operon leader peptide	NA	NA	NA	NA
WP_001223181.1\|4010585_4011272_-\|tRNA	tRNA/rRNA methyltransferase	NA	NA	NA	NA
WP_001303782.1\|4011671_4011812_-	hypothetical protein	NA	NA	NA	NA
WP_001194358.1\|4011907_4012624_+	two-component system response regulator ArcA	NA	NA	NA	NA
WP_000920333.1\|4012683_4014036_-	cell envelope integrity protein CreD	NA	NA	NA	NA
WP_001219606.1\|4014093_4015518_-	two-component system sensor histidine kinase CreC	Q8QKV7	Ectocarpus_siliculosus_virus	1.6e-09	20.4
WP_001188666.1\|4015517_4016207_-	two-component system response regulator CreB	W8CYM9	Bacillus_phage	2.0e-29	35.3
WP_000875487.1\|4016219_4016693_-	protein CreA	NA	NA	NA	NA
WP_000371666.1\|4016903_4017773_+	MDR efflux pump AcrAB transcriptional activator RobA	NA	NA	NA	NA
WP_000942344.1\|4017769_4018417_-	phosphoglycerate mutase GpmB	NA	NA	NA	NA
WP_001297279.1\|4018468_4018990_+	non-canonical purine NTP phosphatase	NA	NA	NA	NA
WP_000068679.1\|4019074_4019401_-	trp operon repressor	NA	NA	NA	NA
WP_000409451.1\|4019490_4021428_-	murein transglycosylase	A0A1P8CWQ1	Bacillus_phage	4.0e-11	34.8
WP_000046749.1\|4021638_4023306_+	energy-dependent translational throttle protein EttA	A0A1V0SKJ1	Klosneuvirus	3.7e-42	26.4
WP_000093810.1\|4023612_4024845_-	trifunctional nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase/transcriptional regulator NadR	A0A0C5K935	Enterococcus_phage	1.6e-82	42.6
WP_001029698.1\|4024865_4026248_-	DNA repair protein RadA	NA	NA	NA	NA
WP_001132955.1\|4026296_4027265_-	phosphoserine phosphatase	NA	NA	NA	NA
WP_000124605.1\|4027370_4028015_+	YtjB family periplasmic protein	NA	NA	NA	NA
WP_000105887.1\|4028042_4029059_+	lipoate--protein ligase LplA	NA	NA	NA	NA
WP_000224877.1\|4029514_4030234_-	purine-nucleoside phosphorylase	NA	NA	NA	NA
WP_000816471.1\|4030313_4031537_-	phosphopentomutase	NA	NA	NA	NA
WP_000477808.1\|4031588_4032911_-	thymidine phosphorylase	A0A0H3UZD4	Geobacillus_virus	1.4e-79	39.8
WP_025651378.1\|4033037_4033817_-	deoxyribose-phosphate aldolase	NA	NA	NA	NA
WP_001143246.1\|4034074_4035625_+	YjjI family glycine radical enzyme	NA	NA	NA	NA
WP_001088405.1\|4035596_4036460_+	YjjW family glycine radical enzyme activase	NA	NA	NA	NA
WP_000563061.1\|4036572_4037355_-	metal-dependent hydrolase	NA	NA	NA	NA
WP_001299799.1\|4037351_4038425_-	patatin family protein	NA	NA	NA	NA
WP_000490275.1\|4038546_4038708_-	DUF1328 domain-containing protein	A0A0N7CBR2	Salmonella_phage	1.8e-10	64.2
WP_001295748.1\|4038834_4039440_-	molecular chaperone OsmY	NA	NA	NA	NA
WP_000202562.1\|4039832_4041419_-	peptide chain release factor 3	D0R0F5	Streptococcus_phage	5.3e-30	24.9
WP_048943363.1\|4041638_4041899_+	DinI-like family protein	A5LH55	Enterobacteria_phage	3.1e-36	95.1
WP_005025120.1\|4042258_4043863_+	TIR domain-containing protein	NA	NA	NA	NA
WP_048943362.1\|4044307_4044892_-\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	1.3e-103	94.8
WP_073546634.1\|4044891_4048242_-	short-chain fatty acid transporter	X2KTY7	Enterobacteria_phage	7.3e-13	39.1
WP_000090892.1\|4051684_4052317_-\|tail	tail assembly protein	C6ZCZ4	Enterobacteria_phage	2.7e-94	98.1
WP_048943354.1\|4052253_4052997_-\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	1.8e-145	95.5
WP_001152502.1\|4053002_4053701_-\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	8.9e-131	97.8
WP_000847345.1\|4053700_4054030_-\|tail	phage tail protein	A0A0K2FIE9	Enterobacteria_phage	8.1e-58	98.2
WP_048943353.1\|4054026_4056588_-\|tail	phage tail tape measure protein	A0A2R9YJM8	Escherichia_phage	0.0e+00	90.3
WP_000459457.1\|4056580_4057015_-\|tail	phage tail assembly protein T	A0A0K2FJB3	Enterobacteria_phage	6.9e-65	100.0
WP_001357868.1\|4056996_4057419_-\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	8.2e-71	96.4
WP_048943399.1\|4057434_4058175_-\|tail	phage tail protein	A0A0K2FJ05	Enterobacteria_phage	6.1e-130	98.0
WP_000683111.1\|4058182_4058578_-\|tail	tail protein	A0A0K2FIF4	Enterobacteria_phage	5.0e-70	99.2
WP_048943351.1\|4058574_4059153_-\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	5.9e-80	97.9
WP_000752996.1\|4059164_4059518_-\|tail	tail attachment protein	A0A2R9YJJ5	Escherichia_phage	1.5e-62	99.1
WP_048943350.1\|4059529_4059925_-	DNA-packaging protein FI	A0A2R9YJP4	Escherichia_phage	2.4e-56	93.2
WP_048943349.1\|4059966_4060992_-\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	9.0e-188	97.4
WP_001338090.1\|4061047_4061380_-\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	6.5e-55	99.1
WP_048943348.1\|4061389_4062709_-	S49 family peptidase	A0A2I6TC87	Escherichia_phage	3.8e-231	97.9
WP_032358757.1\|4062689_4064291_-\|portal	phage portal protein	A0A0K2FJC0	Enterobacteria_phage	1.1e-309	99.2
WP_000198149.1\|4064287_4064494_-\|head,tail	Lambda prophage-derived head-to-tail joining protein W	A0A2R9YJL2	Escherichia_phage	5.8e-30	100.0
WP_001027268.1\|4064490_4066416_-\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	0.0e+00	99.7
WP_000453611.1\|4066390_4066936_-	DNA-packaging protein	A0A0K2FIG2	Enterobacteria_phage	2.3e-94	98.3
WP_001663509.1\|4067324_4067558_+	DUF3950 domain-containing protein	A0A0K2FIR8	Escherichia_phage	2.5e-21	96.3
WP_000079508.1\|4067614_4068025_+	DUF1398 domain-containing protein	C6ZCX4	Enterobacteria_phage	1.3e-52	76.3
WP_001139678.1\|4068376_4068529_-	hypothetical protein	K7PKL2	Enterobacteria_phage	3.1e-20	96.0
WP_001228702.1\|4068557_4068764_-	hypothetical protein	H6WRZ6	Salmonella_phage	5.3e-31	98.5
WP_122654012.1\|4068767_4068959_-	hypothetical protein	NA	NA	NA	NA
WP_048943344.1\|4068980_4069514_-	lysozyme	K7PLY1	Enterobacteria_phage	5.3e-99	94.9
WP_000370550.1\|4069619_4069892_+	hypothetical protein	NA	NA	NA	NA
WP_001468348.1\|4069857_4070202_-	YdfR family protein	K7PGU6	Enterobacteria_phage	4.4e-38	96.4
WP_000839596.1\|4070206_4070422_-\|lysis	phage lysis protein EssD	A5LH82	Enterobacteria_phage	9.0e-34	100.0
WP_000799656.1\|4070489_4071542_-	site-specific DNA-methyltransferase	A5LH81	Enterobacteria_phage	2.7e-208	100.0
WP_000917724.1\|4071692_4071896_-	hypothetical protein	A0A291AWX6	Escherichia_phage	6.1e-32	100.0
WP_001047110.1\|4072149_4072902_-	antitermination protein	K7PGU5	Enterobacteria_phage	5.3e-137	99.2
WP_001433852.1\|4072915_4073905_-	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	1.9e-195	99.7
WP_001061397.1\|4073912_4074710_-	KilA-N domain-containing protein	A0A0P0ZCS0	Stx2-converting_phage	4.4e-150	99.6
WP_000767103.1\|4074729_4075119_-	RusA family crossover junction endodeoxyribonuclease	A5LH74	Enterobacteria_phage	1.0e-67	98.4
WP_000210170.1\|4075115_4075442_-	LexA family transcriptional regulator	A0A291AWY9	Escherichia_phage	5.4e-54	100.0
WP_001442792.1\|4075438_4076092_-	phage N-6-adenine-methyltransferase	A5LH72	Enterobacteria_phage	4.7e-126	98.6
WP_074400546.1\|4076091_4076586_-	PerC family transcriptional regulator	U5P0U0	Shigella_phage	1.7e-83	93.9
WP_000104941.1\|4076582_4077524_-	helix-turn-helix domain-containing protein	U5P0A0	Shigella_phage	6.4e-140	93.0
4076905:4076919	attL	NA	NA	NA	NA
WP_001250269.1\|4077513_4077693_-	DUF4222 domain-containing protein	S5M7S5	Escherichia_phage	7.8e-15	68.5
WP_000526668.1\|4077868_4078426_-	protein YmfL	S5FXP0	Shigella_phage	1.7e-95	94.6
WP_001191669.1\|4078418_4078679_-	helix-turn-helix transcriptional regulator	K7PJQ8	Enterobacteria_phage	5.4e-41	100.0
WP_001020632.1\|4078776_4079469_+	helix-turn-helix transcriptional regulator	S5FUZ3	Shigella_phage	6.4e-121	96.5
WP_000135680.1\|4080171_4080534_+	hypothetical protein	Q8SBF8	Shigella_phage	8.6e-61	100.0
WP_000081316.1\|4080599_4081424_+	DUF2303 family protein	U5P439	Shigella_phage	2.3e-149	99.6
WP_000008209.1\|4081551_4082088_+	5'-deoxynucleotidase	U5P0T3	Shigella_phage	1.6e-100	98.9
WP_001242723.1\|4082078_4082441_+	phage protein	U5P092	Shigella_phage	4.4e-65	95.8
WP_000206803.1\|4082440_4083061_+	DUF551 domain-containing protein	A5LH60	Enterobacteria_phage	2.2e-112	91.3
WP_048943335.1\|4083457_4087285_-	hypothetical protein	NA	NA	NA	NA
WP_001218277.1\|4087467_4088691_-\|integrase	site-specific integrase	A5LH57	Enterobacteria_phage	4.0e-235	98.5
4089869:4089883	attR	NA	NA	NA	NA

DBSCAN-SWA_8

4507682 : 4627393

112

Escherichia_phage(45.0%)

integrase,protease,tRNA,plate,tail,portal,terminase

attL 4531356:4531379|attR 4611439:4611462

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000187022.1\|4507682_4508783_+\|tRNA	tRNA (uridine(54)-C5)-methyltransferase TrmA	NA	NA	NA	NA
WP_000806411.1\|4508822_4509182_-	YijD family membrane protein	NA	NA	NA	NA
WP_001309117.1\|4509181_4509832_-	HTH-type transcriptional repressor FabR	NA	NA	NA	NA
WP_001120810.1\|4510162_4511563_+	Si-specific NAD(P)(+) transhydrogenase	NA	NA	NA	NA
WP_001025939.1\|4511545_4512463_-	DNA-binding transcriptional regulator OxyR	NA	NA	NA	NA
WP_000382183.1\|4512714_4513998_-	MFS transporter	NA	NA	NA	NA
WP_154139580.1\|4514064_4515258_-	D-galactonate dehydratase family protein	Q6A202	Oenococcus_phage	7.5e-45	28.7
WP_001230081.1\|4516553_4517927_-	argininosuccinate lyase	NA	NA	NA	NA
WP_001302318.1\|4517987_4518764_-	acetylglutamate kinase	NA	NA	NA	NA
WP_000935370.1\|4518771_4519776_-	N-acetyl-gamma-glutamyl-phosphate reductase	NA	NA	NA	NA
WP_001389399.1\|4519929_4521081_+	acetylornithine deacetylase	NA	NA	NA	NA
WP_001005579.1\|4521432_4524084_+	phosphoenolpyruvate carboxylase	NA	NA	NA	NA
WP_000556278.1\|4524266_4526000_+	phosphoethanolamine transferase CptA	NA	NA	NA	NA
WP_000274621.1\|4526148_4527000_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000323849.1\|4526986_4527328_-	PTS fructose-like transporter subunit IIB	NA	NA	NA	NA
WP_154139582.1\|4527329_4528208_-	[formate-C-acetyltransferase]-activating enzyme	NA	NA	NA	NA
WP_000184831.1\|4528173_4530471_-	formate C-acetyltransferase	A0A1S6UAD4	Serratia_phage	4.6e-06	48.1
WP_000161265.1\|4530521_4530842_-	PTS fructose-like transporter subunit IIB	NA	NA	NA	NA
WP_025652848.1\|4530856_4531936_-	PTS fructose transporter subunit EIIC	NA	NA	NA	NA
4531356:4531379	attL	NA	NA	NA	NA
WP_001174083.1\|4532244_4534746_+	phosphoenolpyruvate--protein phosphotransferase	A0A1V0SGR7	Hokovirus	1.0e-11	26.9
WP_000424845.1\|4534757_4535420_+	fructose-6-phosphate aldolase	A0A0E3F0E2	Synechococcus_phage	5.5e-29	34.6
WP_000374004.1\|4535430_4536534_+	bifunctional L-1,2-propanediol dehydrogenase/glycerol dehydrogenase	NA	NA	NA	NA
WP_000647882.1\|4536808_4537426_+	DUF1287 domain-containing protein	NA	NA	NA	NA
WP_001341951.1\|4537452_4538358_-	cystine transporter YijE	NA	NA	NA	NA
WP_001297636.1\|4538451_4540632_-	catalase/peroxidase HPI	NA	NA	NA	NA
WP_000007523.1\|4540960_4541851_-	methylenetetrahydrofolate reductase	NA	NA	NA	NA
WP_000110772.1\|4542199_4544632_-	bifunctional aspartate kinase/homoserine dehydrogenase II	NA	NA	NA	NA
WP_001297633.1\|4544634_4545795_-	cystathionine gamma-synthase	NA	NA	NA	NA
WP_000852812.1\|4546071_4546389_+	met regulon transcriptional regulator MetJ	NA	NA	NA	NA
WP_000797341.1\|4546572_4547181_+	YiiX family permuted papain-like enzyme	NA	NA	NA	NA
WP_097412863.1\|4548412_4552510_-	RHS repeat protein	A0A2H4JFP5	uncultured_Caudovirales_phage	2.8e-22	33.2
WP_000710769.1\|4552669_4552882_-	50S ribosomal protein L31	NA	NA	NA	NA
WP_001325632.1\|4553084_4555283_+	primosomal protein N'	NA	NA	NA	NA
WP_000644904.1\|4555438_4556464_+	DNA-binding transcriptional regulator CytR	NA	NA	NA	NA
WP_000068834.1\|4556555_4557515_+	cell division protein FtsN	NA	NA	NA	NA
WP_000208242.1\|4557607_4558138_+\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_001293343.1\|4558147_4559479_+	HslU--HslV peptidase ATPase subunit	A0A191ZC11	Erwinia_phage	1.7e-45	29.9
WP_000139496.1\|4559545_4560472_+	1,4-dihydroxy-2-naphthoate polyprenyltransferase	NA	NA	NA	NA
WP_000872908.1\|4560564_4561050_+	ribonuclease E activity regulator RraA	NA	NA	NA	NA
WP_001296623.1\|4561134_4561380_-	septal ring assembly protein ZapB	NA	NA	NA	NA
WP_000084268.1\|4561804_4562650_+	glycerol uptake facilitator protein GlpF	M1HWZ0	Paramecium_bursaria_Chlorella_virus	4.4e-15	28.0
WP_000136788.1\|4562672_4564181_+	glycerol kinase GlpK	NA	NA	NA	NA
WP_001250644.1\|4564315_4565326_+	class II fructose-bisphosphatase	NA	NA	NA	NA
WP_000796320.1\|4565422_4566169_+	ferredoxin--NADP(+) reductase	NA	NA	NA	NA
WP_000323556.1\|4566173_4566602_-	universal stress protein UspD	NA	NA	NA	NA
WP_000655986.1\|4566628_4566928_-	DUF406 domain-containing protein	NA	NA	NA	NA
WP_000155254.1\|4567139_4567580_-	DUF805 domain-containing protein	NA	NA	NA	NA
WP_000802226.1\|4567680_4568280_+	YiiQ family protein	NA	NA	NA	NA
WP_001216325.1\|4568387_4569155_+	triose-phosphate isomerase	NA	NA	NA	NA
WP_000708998.1\|4569209_4569965_-	CDP-diacylglycerol diphosphatase	NA	NA	NA	NA
WP_001045689.1\|4570071_4571061_-	sulfate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000591795.1\|4571380_4572343_-	6-phosphofructokinase	NA	NA	NA	NA
WP_001076742.1\|4572523_4573426_-	CDF family cation-efflux transporter FieF	NA	NA	NA	NA
WP_000468308.1\|4573662_4573881_-	prophage transcriptional regulator OgrK	A0A0F7LDQ9	Escherichia_phage	4.7e-38	100.0
WP_001598749.1\|4573962_4575126_-	phage late control D family protein	U5N3V4	Enterobacteria_phage	1.4e-205	99.5
WP_000978896.1\|4575125_4575605_-\|tail	phage tail protein	A0A0F7LDE8	Escherichia_phage	6.6e-85	100.0
WP_001598748.1\|4575619_4578067_-\|tail	phage tail tape measure protein	Q7Y4C8	Escherichia_virus	0.0e+00	96.9
WP_000785970.1\|4578059_4578179_-\|tail	GpE family phage tail protein	A0A0F7LCR6	Escherichia_phage	1.0e-15	100.0
WP_001031303.1\|4578211_4578487_-\|tail	phage tail assembly protein	A0A0F7LDQ8	Escherichia_phage	5.7e-41	100.0
WP_001251408.1\|4578543_4579062_-\|tail	phage major tail tube protein	A0A0F7LDZ1	Escherichia_phage	1.4e-93	100.0
WP_001286698.1\|4579074_4580265_-\|tail	phage tail sheath protein	A0A0F7LBW9	Escherichia_phage	3.7e-225	99.7
WP_023993658.1\|4580324_4580918_-	recombinase family protein	A0A0F7LA37	Escherichia_phage	3.9e-103	96.4
WP_154139607.1\|4580948_4581452_+\|tail	phage tail protein	Q9MCR6	Enterobacteria_phage	5.6e-58	72.6
WP_154139584.1\|4581451_4582045_+\|tail	tail fiber assembly protein	M1SV83	Escherichia_phage	9.2e-60	64.3
WP_154139586.1\|4582016_4582457_-\|tail	tail fiber assembly protein	A0A0F7LDZ0	Escherichia_phage	3.4e-51	66.7
WP_154139588.1\|4582459_4583644_-\|tail	phage tail protein	A0A0F7LBW5	Escherichia_phage	4.0e-163	78.4
WP_001285307.1\|4583640_4584252_-\|tail	phage tail protein I	A0A0F7LA36	Escherichia_phage	2.4e-116	99.5
WP_001121474.1\|4584244_4585153_-\|plate	baseplate assembly protein	A0A0F7LCJ3	Escherichia_phage	1.2e-162	100.0
WP_006778006.1\|4585157_4585505_-	protein 25-like lysozyme	A0A0F7L9X3	Escherichia_phage	8.5e-58	99.1
WP_154139609.1\|4585754_4586009_+\|terminase	terminase	A0A0F7LCM8	Escherichia_phage	1.3e-34	98.7
WP_001598738.1\|4586008_4587043_+\|portal	phage portal protein	M1SV64	Escherichia_phage	1.9e-201	99.7
WP_001161722.1\|4587469_4588411_+	hypothetical protein	Q2P9W7	Enterobacteria_phage	2.0e-133	73.7
WP_001389947.1\|4588493_4588976_-	hypothetical protein	NA	NA	NA	NA
WP_000119270.1\|4589159_4589645_-	ImmA/IrrE family metallo-endopeptidase	Q854W5	Mycobacterium_virus	6.0e-09	37.1
WP_001598736.1\|4590782_4593059_-	replication endonuclease	A0A0F7LBQ2	Escherichia_phage	0.0e+00	98.3
WP_000027673.1\|4593048_4593324_-	hypothetical protein	S4TP00	Salmonella_phage	1.9e-44	97.8
WP_001113277.1\|4593320_4593545_-	hypothetical protein	S4TRY6	Salmonella_phage	6.5e-35	98.6
WP_001277898.1\|4593547_4593847_-	hypothetical protein	S4TUD1	Salmonella_phage	3.2e-45	99.0
WP_000557703.1\|4593846_4594071_-	DUF2732 family protein	S4TP68	Salmonella_phage	4.7e-33	100.0
WP_000217670.1\|4594134_4594635_-	hypothetical protein	M1SV55	Escherichia_phage	2.6e-92	100.0
WP_001308179.1\|4594804_4595077_-	hypothetical protein	Q1JS36	Enterobacteria_phage	1.4e-47	100.0
WP_001598735.1\|4595213_4595507_+	helix-turn-helix domain-containing protein	Q1JS37	Enterobacteria_phage	6.1e-49	99.0
WP_000985246.1\|4595576_4596557_+\|integrase	tyrosine-type recombinase/integrase	S4TP66	Salmonella_phage	4.7e-186	100.0
WP_001223800.1\|4596743_4597244_-	cell-envelope stress modulator CpxP	NA	NA	NA	NA
WP_001033722.1\|4597393_4598092_+	envelope stress response regulator transcription factor CpxR	Q6XM27	Feldmannia_irregularis_virus	5.3e-06	30.3
WP_000580417.1\|4598088_4599462_+	envelope stress sensor histidine kinase CpxA	W8CYF6	Bacillus_phage	3.8e-16	25.9
WP_001166063.1\|4600390_4601374_-	2-keto-3-deoxygluconate transporter	NA	NA	NA	NA
WP_001297064.1\|4601633_4602254_-	superoxide dismutase [Mn]	Q56AR7	Bacillus_thuringiensis_phage	4.9e-64	59.8
WP_000063502.1\|4602538_4603573_+	L-rhamnose/proton symporter RhaT	NA	NA	NA	NA
WP_001296618.1\|4603569_4604508_-	HTH-type transcriptional activator RhaR	NA	NA	NA	NA
WP_000217137.1\|4604491_4605328_-	HTH-type transcriptional activator RhaS	NA	NA	NA	NA
WP_000144052.1\|4605615_4607085_+	rhamnulokinase	NA	NA	NA	NA
WP_001325794.1\|4607081_4608341_+	L-rhamnose isomerase	NA	NA	NA	NA
WP_001179764.1\|4608582_4609407_+	rhamnulose-1-phosphate aldolase	NA	NA	NA	NA
WP_000619503.1\|4609416_4609731_+	L-rhamnose mutarotase	NA	NA	NA	NA
WP_000729595.1\|4610043_4610490_+	PTS fructose transporter subunit IIA	NA	NA	NA	NA
WP_000446026.1\|4610500_4611952_+	PTS fructose-like transporter subunit IIBC	NA	NA	NA	NA
4611439:4611462	attR	NA	NA	NA	NA
WP_001019461.1\|4611941_4613012_+	aminopeptidase	NA	NA	NA	NA
WP_000931336.1\|4613011_4614760_+	HTH domain-containing protein	NA	NA	NA	NA
WP_001317404.1\|4614809_4615850_-	YiiG family protein	NA	NA	NA	NA
WP_000753583.1\|4616002_4616836_-	formate dehydrogenase accessory sulfurtransferase FdhD	NA	NA	NA	NA
WP_011310337.1\|4617029_4620080_+	formate dehydrogenase-N subunit alpha	A0A077SK27	Escherichia_phage	1.1e-07	23.8
WP_000331377.1\|4620092_4620995_+	formate dehydrogenase subunit beta	NA	NA	NA	NA
WP_000829013.1\|4620991_4621627_+	formate dehydrogenase cytochrome b556 subunit	NA	NA	NA	NA
WP_000027708.1\|4621623_4622553_+	formate dehydrogenase accessory protein FdhE	NA	NA	NA	NA
WP_001086388.1\|4622882_4623125_-	hypothetical protein	NA	NA	NA	NA
WP_001295676.1\|4623343_4623562_-	CopG family transcriptional regulator	NA	NA	NA	NA
WP_000356397.1\|4624166_4624457_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_000897305.1\|4624457_4624769_-	hypothetical protein	NA	NA	NA	NA
WP_001162704.1\|4624997_4625906_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_001297068.1\|4625969_4626911_-	fatty acid biosynthesis protein FabY	NA	NA	NA	NA
WP_000560983.1\|4626955_4627393_-\|tRNA	D-tyrosyl-tRNA(Tyr) deacylase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP045998

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1111 : 52796

Escherichia_phage(55.56%)

integrase,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001067855.1\|1111_1816_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_124354296.1\|2125_5158_+\|transposase	Tn3 family transposase	NA	NA	NA	NA
WP_154139449.1\|5097_5808_-\|transposase	IS6 family transposase	A0A077SL39	Escherichia_phage	5.5e-120	96.7
WP_148245969.1\|5772_6300_+	MFS transporter	NA	NA	NA	NA
WP_001137892.1\|6299_6884_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_001389365.1\|7376_8141_-\|transposase	IS6-like element IS6100 family transposase	A0A077SL39	Escherichia_phage	4.3e-86	65.7
WP_001323889.1\|8477_10055_+	PAS domain-containing protein	A0A1B0V854	Salmonella_phage	1.2e-95	99.4
WP_002210513.1\|10382_11144_+	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	1.9e-134	100.0
WP_002904004.1\|11164_12025_-	class A extended-spectrum beta-lactamase SHV-12	A0A077SL40	Escherichia_phage	2.2e-155	99.3
WP_001067855.1\|12161_12866_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_103859199.1\|13671_15231_+	ABC-F family ATP-binding cassette domain-containing protein	A0A2H4UUX5	Bodo_saltans_virus	1.5e-16	24.4
WP_000844627.1\|15958_16201_+\|transposase	transposase	NA	NA	NA	NA
WP_072109431.1\|16232_16895_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_000804063.1\|16973_18173_+	tetracycline efflux MFS transporter Tet(A)	NA	NA	NA	NA
WP_001255015.1\|18439_18745_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_058657119.1\|18772_19987_-	chloramphenicol/florfenicol efflux MFS transporter FloR	S4TR35	Salmonella_phage	5.5e-19	28.7
WP_012728215.1\|20203_21088_-	DUF3363 domain-containing protein	NA	NA	NA	NA
WP_001120888.1\|21118_22612_-\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_094309310.1\|22950_24108_-	tetracycline-inactivating monooxygenase Tet(X)	NA	NA	NA	NA
WP_094309312.1\|24097_25015_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_001067858.1\|25289_25994_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.2e-138	99.6
WP_065799592.1\|26005_26818_-	lincosamide nucleotidyltransferase Lnu(F)	NA	NA	NA	NA
WP_001206356.1\|26949_27741_-	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA2	NA	NA	NA	NA
WP_154139451.1\|27886_28651_+\|integrase	integron integrase	A0A1P8DJJ6	Virus_Rctr41k	1.3e-26	36.9
WP_033545665.1\|28541_29246_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	9.0e-139	99.6
WP_024245155.1\|30043_30682_-	resolvase	A0A1V0E035	Clostridioides_phage	1.9e-07	27.1
WP_000864791.1\|30967_31588_+	ParA family protein	A2I303	Vibrio_virus	1.1e-18	33.8
WP_000051064.1\|31639_31870_+	partitioning protein	NA	NA	NA	NA
WP_015060510.1\|31885_32179_+	hypothetical protein	NA	NA	NA	NA
WP_154139453.1\|32225_33149_+\|transposase	IS5 family transposase	Q9MCT5	Escherichia_phage	5.4e-176	99.3
WP_031942371.1\|33208_33631_-	DNA distortion polypeptide 3	NA	NA	NA	NA
WP_001074386.1\|33698_34145_-	hypothetical protein	NA	NA	NA	NA
WP_001050931.1\|34184_35021_-	replication initiation protein	NA	NA	NA	NA
WP_000121743.1\|36276_36528_+	plasmid stabilization protein	NA	NA	NA	NA
WP_000220560.1\|36517_36799_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A2H4JBF4	uncultured_Caudovirales_phage	3.8e-24	62.4
WP_001181903.1\|36944_37268_+	hypothetical protein	A0A0K1LL53	Rhodobacter_phage	9.2e-14	46.1
WP_000356546.1\|37312_37558_+	hypothetical protein	NA	NA	NA	NA
WP_001180116.1\|37547_37763_+	hypothetical protein	NA	NA	NA	NA
WP_000866648.1\|37855_38185_+	hypothetical protein	NA	NA	NA	NA
WP_000160399.1\|38633_38906_+	hypothetical protein	NA	NA	NA	NA
WP_038976855.1\|39232_39778_+	hypothetical protein	NA	NA	NA	NA
WP_000538023.1\|39780_40938_+	hypothetical protein	NA	NA	NA	NA
WP_000872475.1\|41298_41790_+	transcription termination factor NusG	NA	NA	NA	NA
WP_000953539.1\|42014_42659_+	lytic transglycosylase domain-containing protein	NA	NA	NA	NA
WP_000921916.1\|42642_42933_+	TrbC/VirB2 family protein	NA	NA	NA	NA
WP_000108725.1\|42956_45716_+	conjugal transfer protein	NA	NA	NA	NA
WP_000737859.1\|45717_46455_+	pilus assembly protein	NA	NA	NA	NA
WP_001228869.1\|46464_46725_+	EexN family lipoprotein	NA	NA	NA	NA
WP_000235774.1\|46736_47792_+	type IV secretion system protein	NA	NA	NA	NA
WP_000394570.1\|47981_48704_+	type IV secretion system protein	NA	NA	NA	NA
WP_025755764.1\|48709_49639_+	conjugal transfer protein	NA	NA	NA	NA
WP_025755765.1\|49635_50850_+	TrbI/VirB10 family protein	NA	NA	NA	NA
WP_154139455.1\|50867_51578_+	type II/IV secretion system protein	NA	NA	NA	NA
WP_085948178.1\|51583_52796_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP045999

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP046000

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_CP045998

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection