CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP046115	Klebsiella oxytoca strain P620 chromosome, complete genome	6 crisprs	DEDDh,WYL,DinG,cas3,csa3	0	8	2	0

1. NZ_CP046115

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP046115_1

• CRISPR_ID: NZ_CP046115_1
• CRISPR_location: 1924664-1924871
• CRISPR_type: Orphan
• Repeat_type: I-F
• Spacer_info: 3 spacers

Consensus repeat of NZ_CP046115_1

Consensus_repeat	Method
GTTCACTGCCGTACAGGCAGCTTAGAAAA	PILER-CR
GTTCACTGCCGTACAGGCAGCTTAGAAA	CRISPRCasFinder

spacers of NZ_CP046115_1

>1.1|1924693|31|NZ_CP046115|PILER-CR
ATCTGCTCAGTCAGATTGCGGGACACTTCAC
>1.2|1924753|31|NZ_CP046115|PILER-CR
AAAACGAACGCGACCAGGGGATGGAGCGTTT
>1.3|1924692|32|NZ_CP046115|CRISPRCasFinder
GATCTGCTCAGTCAGATTGCGGGACACTTCAC
>1.4|1924752|32|NZ_CP046115|CRISPRCasFinder
AAAAACGAACGCGACCAGGGGATGGAGCGTTT
>1.5|1924812|32|NZ_CP046115|CRISPRCasFinder
AGTTAACAGACAAGCGTCTAAGCCGGCTTCAT

CRISPR arrays and Neighbor proteins around NZ_CP046115_1

CRISPR arrays

The CRISPR arrays of NZ_CP046115_1

>merge|NZ_CP046115|1|1924664-1924871|PILER-CR,CRISPRCasFinder
GTTCACTGCCGTACAGGCAGCTTAGAAAGATCTGCTCAGTCAGATTGCGGGACACTTCACGTTCACTGCCGTACAGGCAGCTTAGAAAAAAAACGAACGCGACCAGGGGATGGAGCGTTTGTTCACTGCCGTACAGGCAGCTTAGAAAAGTTAACAGACAAGCGTCTAAGCCGGCTTCATGTTCATTGCCGAACAGACAGTTTAAAAC

>NZ_CP046115|1|1|1924664-1924812|PILER-CR
GTTCACTGCCGTACAGGCAGCTTAGAAAG	ATCTGCTCAGTCAGATTGCGGGACACTTCAC
GTTCACTGCCGTACAGGCAGCTTAGAAAA	AAAACGAACGCGACCAGGGGATGGAGCGTTT
GTTCACTGCCGTACAGGCAGCTTAGAAAA

>NZ_CP046115|1|1|1924664-1924871|CRISPRCasFinder
GTTCACTGCCGTACAGGCAGCTTAGAAA	GATCTGCTCAGTCAGATTGCGGGACACTTCAC
GTTCACTGCCGTACAGGCAGCTTAGAAA	AAAAACGAACGCGACCAGGGGATGGAGCGTTT
GTTCACTGCCGTACAGGCAGCTTAGAAA	AGTTAACAGACAAGCGTCTAAGCCGGCTTCAT
GTTCATTGCCGAACAGACAGTTTAAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046115.1|WP_154679868.1|1915566_1916295_-|arginine-ABC-transporter-ATP-binding-protein-ArtP	unknown	unknown	gnl|CDD|182980
NZ_CP046115.1|WP_154679869.1|1916671_1917187_-|lipoprotein	unknown	unknown	gnl|CDD|182526
NZ_CP046115.1|WP_004130898.1|1935427_1935745_+|ATP-dependent-Clp-protease-adapter-ClpS	unknown	unknown	gnl|CDD|225038
NZ_CP046115.1|WP_154679881.1|1931745_1932861_+|macrolide-transporter-subunit-MacA	unknown	unknown	gnl|CDD|183211
NZ_CP046115.1|WP_154679874.1|1921005_1922004_-|low-specificity-L-threonine-aldolase	unknown	unknown	gnl|CDD|236710
NZ_CP046115.1|WP_154679871.1|1917624_1918455_+|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl|CDD|225567
NZ_CP046115.1|WP_154682674.1|1927804_1928704_-|DUF340-domain-containing-protein	unknown	unknown	gnl|CDD|225287
NZ_CP046115.1|WP_154679873.1|1919561_1920995_-|DUF2867-domain-containing-protein	unknown	unknown	gnl|CDD|187556
NZ_CP046115.1|WP_154679875.1|1922159_1923878_-|ubiquinone-dependent-pyruvate-dehydrogenase	unknown	unknown	gnl|CDD|181661
NZ_CP046115.1|WP_154679879.1|1928827_1929523_-|aquaporin-Z	unknown	unknown	gnl|CDD|235453
NZ_CP046115.1|WP_154679872.1|1918451_1919465_-|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|223528
NZ_CP046115.1|WP_154679882.1|1932857_1934804_+|macrolide-ABC-transporter-ATP-binding-protein/permease-MacB	unknown	unknown	gnl|CDD|182528
NZ_CP046115.1|WP_154679867.1|1914815_1915547_-|arginine-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|184969
NZ_CP046115.1|WP_154679878.1|1926006_1927659_-|hydroxylamine-reductase	unknown	unknown	gnl|CDD|235391
NZ_CP046115.1|WP_154679883.1|1935775_1938058_+|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA	unknown	unknown	gnl|CDD|236828
NZ_CP046115.1|WP_154679876.1|1924029_1924464_+|DoxX-family-membrane-protein	unknown	unknown	gnl|CDD|311556
NZ_CP046115.1|WP_004100627.1|1934872_1935103_-|cold-shock-like-protein-CspD	unknown	unknown	gnl|CDD|184960
NZ_CP046115.1|WP_154679870.1|1917304_1917628_+|heavy-metal-binding-domain-containing-protein	unknown	unknown	gnl|CDD|179490
NZ_CP046115.1|WP_154679880.1|1929909_1931568_+|DUF2813-domain-containing-protein	unknown	unknown	gnl|CDD|226121
NZ_CP046115.1|WP_154679877.1|1925028_1925997_-|NADH-oxidoreductase	unknown	unknown	gnl|CDD|236735

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046115.1|WP_154679868.1|1915566_1916295_-|arginine-ABC-transporter-ATP-binding-protein-ArtP	gnl|CDD|182980	PRK11124, artP, arginine transporter ATP-binding subunit; Provisional.	0
NZ_CP046115.1|WP_154679869.1|1916671_1917187_-|lipoprotein	gnl|CDD|182526	PRK10533, PRK10533, putative lipoprotein; Provisional.	4.63543e-114
NZ_CP046115.1|WP_004130898.1|1935427_1935745_+|ATP-dependent-Clp-protease-adapter-ClpS	gnl|CDD|225038	COG2127, COG2127, Uncharacterized conserved protein [Function unknown].	3.43391e-47
NZ_CP046115.1|WP_154679881.1|1931745_1932861_+|macrolide-transporter-subunit-MacA	gnl|CDD|183211	PRK11578, PRK11578, macrolide transporter subunit MacA; Provisional.	0
NZ_CP046115.1|WP_154679874.1|1921005_1922004_-|low-specificity-L-threonine-aldolase	gnl|CDD|236710	PRK10534, PRK10534, L-threonine aldolase; Provisional.	0
NZ_CP046115.1|WP_154679871.1|1917624_1918455_+|N-acetylmuramoyl-L-alanine-amidase	gnl|CDD|225567	COG3023, ampD, N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane].	7.95436e-105
NZ_CP046115.1|WP_154682674.1|1927804_1928704_-|DUF340-domain-containing-protein	gnl|CDD|225287	COG2431, COG2431, Predicted membrane protein [Function unknown].	4.23619e-115
NZ_CP046115.1|WP_154679873.1|1919561_1920995_-|DUF2867-domain-containing-protein	gnl|CDD|187556	cd05245, SDR_a2, atypical (a) SDRs, subgroup 2. This subgroup contains atypical SDRs, one member is identified as Escherichia coli protein ybjT, function unknown. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif consensus that generally matches the extended SDRs, TGXXGXXG, but lacks the characteristic active site residues of the SDRs. This subgroup has basic residues (HXXXR) in place of the active site motif YXXXK, these may have a catalytic role. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	2.24211e-129
NZ_CP046115.1|WP_154679875.1|1922159_1923878_-|ubiquinone-dependent-pyruvate-dehydrogenase	gnl|CDD|181661	PRK09124, PRK09124, ubiquinone-dependent pyruvate dehydrogenase.	0
NZ_CP046115.1|WP_154679879.1|1928827_1929523_-|aquaporin-Z	gnl|CDD|235453	PRK05420, PRK05420, aquaporin Z; Provisional.	8.31749e-145
NZ_CP046115.1|WP_154679872.1|1918451_1919465_-|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|223528	COG0451, WcaG, Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	5.44012e-54
NZ_CP046115.1|WP_154679882.1|1932857_1934804_+|macrolide-ABC-transporter-ATP-binding-protein/permease-MacB	gnl|CDD|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	0
NZ_CP046115.1|WP_154679867.1|1914815_1915547_-|arginine-ABC-transporter-substrate-binding-protein	gnl|CDD|184969	PRK15007, PRK15007, arginine ABC transporter substrate-binding protein.	1.67979e-173
NZ_CP046115.1|WP_154679878.1|1926006_1927659_-|hydroxylamine-reductase	gnl|CDD|235391	PRK05290, PRK05290, hybrid cluster protein; Provisional.	0
NZ_CP046115.1|WP_154679883.1|1935775_1938058_+|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA	gnl|CDD|236828	PRK11034, clpA, ATP-dependent Clp protease ATP-binding subunit; Provisional.	0
NZ_CP046115.1|WP_154679876.1|1924029_1924464_+|DoxX-family-membrane-protein	gnl|CDD|311556	pfam07681, DoxX, DoxX. These proteins appear to have some sequence similarity with pfam04173 but their function is unknown.	5.6801e-12
NZ_CP046115.1|WP_004100627.1|1934872_1935103_-|cold-shock-like-protein-CspD	gnl|CDD|184960	PRK14998, PRK14998, cold shock-like protein CspD; Provisional.	1.34932e-46
NZ_CP046115.1|WP_154679870.1|1917304_1917628_+|heavy-metal-binding-domain-containing-protein	gnl|CDD|179490	PRK02877, PRK02877, hypothetical protein; Provisional.	2.36846e-66
NZ_CP046115.1|WP_154679880.1|1929909_1931568_+|DUF2813-domain-containing-protein	gnl|CDD|226121	COG3593, COG3593, Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair].	0
NZ_CP046115.1|WP_154679877.1|1925028_1925997_-|NADH-oxidoreductase	gnl|CDD|236735	PRK10684, PRK10684, HCP oxidoreductase, NADH-dependent; Provisional.	0

Protein sequences

>NZ_CP046115.1|WP_154679876.1|1924029_1924464_+|DoxX-family-membrane-protein
MVKSLLNTINKLLTHDDFGKFLLRLAVGGLMLFHGLHKLFDGTGAISNMLIAKGLPGFIAYGVLVGEVVAPCLLIVGILTRPAALVLAFTMVVAWLMVGTGKTFALDAVGAWAIENLAYFFIGALAIAFLDAGRYSIGGNSAWR
>NZ_CP046115.1|WP_154679875.1|1922159_1923878_-|ubiquinone-dependent-pyruvate-dehydrogenase
MKQTVAAYIAKTLEQAGVKRIWGVTGDSLNGLSDSLNRMGTIDWMPTRHEEVAAFAAGAEAQLTGELAVCAGSCGPGNLHLINGLFDCHRNHVPVLAIAAHIPSSEIGSGYFQETHPQELFRECSHYCELVSSPEQIPQVLAIAMRKAVINRGVSVVVLPGDVALKAAPESASSHWYHAPLPLVTPPEEELKKLAQLLRYSSNIALMCGSGCAGAHKELVEFAAKLKAPVVHALRGKEHVEYDNPYDVGMTGLIGFSSGFHTMMNADTLVLLGTQFPYRAFYPTDAKIIQIDINPGSIGAHSKVDMALVGDIKSTLSALLPHLEEKTDRKFLDTALEHYRDARKGLDDLAKPSDKTIHPQYLAQRISHFADDDAIFTCDVGTPTVWAARYLQMNGKRRLLGSFNHGSMANAMPQAIGAKATAPNRQVVAMCGDGGFSMLMGDFLSLAQMKLPVKIVIFNNSVLGFVAMEMKAGGYLTDGTELHDTNFARIAEACGIKGIRVESAAEVDEALQTAFSTDGPVLVDVVVAKEELAIPPQIKLEQAKGFSLYMLRAIISGRGDEVIELAKTNWLR
>NZ_CP046115.1|WP_154679874.1|1921005_1922004_-|low-specificity-L-threonine-aldolase
MIDLRSDTVTRPGRAMLEAMMAAPVGDDVYGDDPTVNQLQRFAAELAGKEAAIFLPTGTQANLVALLSHCQRGEEYIVGQGAHNYLYEAGGAAVLGSIQPQPIDAAADGSLPLDKVAAKIKPNDIHFAPTRLLSLENTHNGKVLPREYLQEAWEFTRQRGLGLHVDGARIFNALVEYGCELRDITRYCDSLTICLSKGLGAPVGSLLVGSEEYIRHAIRWRKMVGGGMRQAGILAAAGIYALQNNIERLKEDHDNAAWMAEQLRAAGAEVTRHDTNMLFVRVGEEHAALGEYLRERGVLISASPIVRLVTHIDVNRQQLAEVVNHWRAFLNR
>NZ_CP046115.1|WP_154679873.1|1919561_1920995_-|DUF2867-domain-containing-protein
MSQRILVLGASGYIGQHLVKRLSEQGFTVLAAARRIDRLKKQNLPGVECRSLDLNHPDGLTALLAQADTVYYLVHGMGEGGDFIQHERQVALNVRDALRKTPVSEVIFLSSLQVSEQEQSDHLRARQITADLLRESGVPVTEIRAGIIVGAGSAAFEVMRDMVYNLPVLTPPRWVRSRTTPIALENLLYYLLQLLNHPSREHRIFEAAGPEVLSYQQQFIRFMAVSGKRRPLIPVPLPTSWISVWFLNVITSVPPTTAKALIQGLKHDLIADDRALRALIPQPLIAFDEAVRSTLKEEEQLVNSSDWGYDAQAFARWRPEYGYYPKQAGCTVNTCASLAALWKVVNQIGGKEGYFFGNVLWKTRGAMDLLVGHRLAKGRPEKEYLQTGDTVDSWKVIIVETEKQLTLLFGMKAPGLGRLSFTLRNKGDHRELDVRAWWHPHGMPGLFYWLLMIPAHLFIFRGMARRIARLAEQITSK
>NZ_CP046115.1|WP_154679872.1|1918451_1919465_-|SDR-family-NAD(P)-dependent-oxidoreductase
MKVLVTGATSGLGRNAVEYLRNRGISVRATGRNEAMGKLLSKMGAEFVPADLTELVSSQAKVMLAGIDTLWHCSSFTSPWGTQQAFDLANVRATRRLGEWAVAWGVRNFVHISSPSLYFDYHHHRDIQEDFRPQRFANEFARSKAASEDVINLLAQANPNTRFTILRPQSLFGPHDKVFIPRLAQMMQHYGSVLLPRGGSALVDMTYYENAVHAMWLASQAHCDLLPSARAYNITNGEPQTLHSIVQKLIDELGIKCRIRSVPYPMLDIIARSMERFGNKSAKEPAFTHYGVSKLNFDFTLDISRAQQELSYQPVVTMDEGIIRTAAWLRDHGKLHY
>NZ_CP046115.1|WP_154679871.1|1917624_1918455_+|N-acetylmuramoyl-L-alanine-amidase
MKVCRAGVLLGLLLTGCATEKGIVDRDGYQLDTRHPAQAAYPRIKVLVIHYTADDFDVSLATLTDNQVSSHYLIPEKPPLHKGKPRIWQLVPEEELAWHAGVSFWRGSTRINDTSIGIELENRGWQKTAGIKSFTPFNPAQIDALIPLAKDIIARYHIAPQNVVAHADIAPQRKDDPGPLFPWRRLAEQGIGAWPDAQRVAFYLQGRPSFEPVETAGLLDVLARYGYQVTPEMTPAQQKRVIMAFQMHFRPERWDGVADAQTLAIAEALLEKYGRG
>NZ_CP046115.1|WP_154679870.1|1917304_1917628_+|heavy-metal-binding-domain-containing-protein
MQFSTTPTLEGQPIVEYCGVVTGEAILGANVFRDFFASIRDIVGGRSGAYEKELRKAREIAFAELSEQAKALGANAVVGIDIDYETVGKDSSMLMVSVSGTAVKTQR
>NZ_CP046115.1|WP_154679869.1|1916671_1917187_-|lipoprotein
MRYKVLALVLPCALALSACTTVTPAYKDNGTRSGPCIEGGPDDVAQKFYDYQVQNRNSDLTALRPYLSDGLAKLLNDARQDTSNHALLQSNLFSSSTTPADSADVASASTIPNRDARNIPLRVELKQGTQSWKDEVLMIQEGQCWAVDDVRYLGNNSHAPAGTLRQSLEKR
>NZ_CP046115.1|WP_154679868.1|1915566_1916295_-|arginine-ABC-transporter-ATP-binding-protein-ArtP
MSIKLNGINCFYGAHQALFDITLECPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLYIAGNHFDFTKAPSDKAIRELRQNVGMVFQQYNLWPHLTVQQNLIEAPCRVLGLSKDQALARAEKLLERLRLKPYSDRYPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAALDPEITAQIVSIIRELAETGITQVIVTHEVEVARKTASRVVYMENGHIVEQGDASCFVHPQTDAFKNYLSH
>NZ_CP046115.1|WP_154679867.1|1914815_1915547_-|arginine-ABC-transporter-substrate-binding-protein
MKKVLIAALLAGMSLSATAAQTIRFATEASYPPFESIDANNKIVGFDVDLANALCKEIDATCTFTNQAFDSLIPSLKFRRFDAVMAGMDITPEREKQVLFTTPYYENSALFVGQEGKFTSIDALKGKKVGVQNGTTHQKFITDKHPEITTVPYDSYQNAKLDLQNGRIDAVFGDTAVVTEWLKSNPKLAAVGDKVTDKDYFGTGLGIALRQGNTELQQKFNAALEKVKSDGTYQSIYNKWFQK
>NZ_CP046115.1|WP_154679877.1|1925028_1925997_-|NADH-oxidoreductase
MTMPTAQCPWRMQVHHIHQETPDVWTISLLCHDYYPYRAGQYALVSVRNSAETLRAYTISSTPGVSEYITLTVRRIDDGVGSQWLTRDIKRGDYIWLSDAMGDFTCDDKADDKFLLLAAGCGVTPIMSMRRWLARYRPQADVQVIFNVRSPLDVIFADEWRQYPVTLVAENNATHGFVAGRLTTELLQSVPDLAARTVMTCGPAPYMDLVEQDVKALGATRFFKEQFFTPVAIAATGGLKFSKLQPAKEFYAPVGSTLLEALESNKVPVTAACRAGVCGCCKTKVVSGEYTVSSTMTLTDAEIAEGYVLACSCQPQGDLILA
>NZ_CP046115.1|WP_154679878.1|1926006_1927659_-|hydroxylamine-reductase
MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIAALQGLSAWALKAREYGIIDHGVDSFAPRAFFSTLTNVNFDSPRIVGYARQAIAMREALKAQCLSIDAHATVNNPMAVLQLASDDLGDLQRQAAEFTPNKDKAAIGENILGLRLLCLYGLKGAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPSDMNALLECSMEIGQMNFKVMSILDAGETSKYGHPTPTQVNVKATEGKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLPAHGYPELRKFKHLIGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGAYDDRIWTRSIVGWPGVNHLEGEDFAPVIAQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVSREKLRHIFLVGGCDGARGERNYFTDFATSVPDDCLILTLACGKYRFNKLDFGDIEGLPRLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVKNIVTGPTAPGFFTPDLLAVLNEKFGLRSVTTVEEDMKQLLSA
>NZ_CP046115.1|WP_154682674.1|1927804_1928704_-|DUF340-domain-containing-protein
MFSGLLIILLPLVVGYLIPLRRPSALKLITRLLSWIVYVILFFMGISLAFLDNLASNLLAILHYAAVSVVIILLCNIAALMWLEQKMPWQNKHRQEKLPSRLAMALESLQLCGVVLIGFLIGLSGLSFLQHATEASEYTLIFLLFLIGIQLRNNGMTLRQIVLNRRGMIVAVVVMISSLLGGVINAFILDLPIKTGLAMASGFGWYSLSGILLTESYGPVIGSAAFFNDLARELLAIMLIPGMVSRSRSTALGICGATSMDFTLPVLQRSGGVEIVPAAIVHGFILSLLVPILMAVFSA
>NZ_CP046115.1|WP_154679879.1|1928827_1929523_-|aquaporin-Z
MFRKLAAECFGTFWLVFGGCGSAVLAAAFPELGIGFAGVALAFGLTVLTMAFAVGHISGGHFNPAVTLGLWAGGRFPAKDVIGYIIAQVVGGIIAAAILYIVASGKAGFDAAASGFASNGYGEHSPGGFSMLSAIVIEIVLTCGFLLVIHGATDKNAPAGFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALQQLWLFWVMPIVGGILGGVLYRTLLEKRN
>NZ_CP046115.1|WP_154679880.1|1929909_1931568_+|DUF2813-domain-containing-protein
MHLERVEIVGFRGINRLSLTLEQNNVLIGENAWGKSSLLDALTLLLSPELDLYRFVREDFWFPPGDVLGRERHLHIILTFRENEPGRHRVRRYRPLSSCWVPCEDGYQRVFYRLEGELTDDDSVMTLRSFINGEGEALELDDIDEQARHLVRLMPVLRLRDARFMRRIHNGAVPHTPQIEITARQLDYLSRELMHHPQNLTDGQIRQGLSAMVQLLEHYFAEQSSAQSRNRLMRRYSHDEQRSWRYLDIINRMIDKPGGRSHRVILLGLFSTLLQAKGTVRLDRDARPLLLIEDPETRLHPIMLSVAWHLLNLLPLQRVTTTNSGELLSLTPVEHVCRLVRESSRVSAWRLGPGGMNAEDSRRIAFHIRFNRASSLFARCWLLVEGETETWVINELARQCGHHFDAEGVKVIEFAQSGLKPLIKFARRMGIEWHVLVDGDEAGKKYAATVRGLLNDDKTLERDHLTTLPAMDMEHFMYRQGFDDVYHRVAQLPMNIPMNMRRVITKAIHRSSKPDLAIEVAMEAGRRGVDAIPTLLKKMFSRVLWLARGRAD
>NZ_CP046115.1|WP_154679881.1|1931745_1932861_+|macrolide-transporter-subunit-MacA
MKLNGKRRKVWWLLAIVVLALAVWGWRILNVPLPQYQTLVVRKGDLQQSVLATGKLDALKKVDVGAQVSGQLKTLRVEIGDKVKKDQLLGVIDPEQAENQIKEVEATLMELRAQLNQAQAERKLSAATLARQQQLAQRQLVSRQDLDTAATDLAVKEAQIGTIEAQVKRNQATLDTAKTNLDYTKILAPMSGEVTQITTLQGQTVIAAQQAPNILTLADLSTMLVKAQVSEADVIHLKPGQKAWFTVLGDPLTRYEGTLKDILPTPEKVNDAIFYYARFEVPNPEGILRLEMTAQVHIQLSEVKNIITIPLSALGEAIGDNRYRVRLLRTGEVKEREIVIGARNDTDVAVVKGLEEGDEVIIGEGAAGAAK
>NZ_CP046115.1|WP_154679882.1|1932857_1934804_+|macrolide-ABC-transporter-ATP-binding-protein/permease-MacB
MTALLELHDIRRSYPSGDGHVDVLKGITLSIAAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGTDVAHLNGDELARLRREHFGFIFQRYHLLSHLTAAQNVEVPAVYAGAERKARLARAHELLVRLGLGDRAEYQPSQLSGGQQQRVSIARALMNGGEVILADEPTGALDSRSGEEVMGILHQLKAQGHTVIIVTHDPQVAAQAERVIEIHDGEIVRNPPALSPAQGGVLRQRTAAEPSAWRQFSSGFREALIMAWRAMAANKMRTLLTMLGIIIGIASVVSIVVVGDAAKQMVLADIRAIGTNTIDVYPGKDFGDDDPRYQQSLKYDDLLAIQKQPWVSSATPAVSKSLRLRADNIDVAASAEGVGAQYFNVYGMTFSEGNTFNELQLNSRAQVVVLDSNARRQLFPHKAKVVGEIILVGNMPAKVIGVADEKQSMFGSSKILRVWLPYTTMAGRVMGQSWLNSITVRVNEGYDSAVAEQQLLRLLELRHGKKDVFTWNMDSILKTAERTTHTLQLFLTLVAVIALVVGGIGVMNIMLVSVTERTREIGIRMAVGARASDVLQQFLIEAVLVCLVGGALGVTLSLLIAFVLQLFLPGWEIGFSPLALLTAFLCSTLTGVLFGWLPARNAARLDPVDALARE
>NZ_CP046115.1|WP_004100627.1|1934872_1935103_-|cold-shock-like-protein-CspD
MEMGTVKWFNNAKGFGFICPEGGGEDIFAHYSTIQMDGYRTLKAGQAVRFDVHQGPKGNHASVIVPVEAEETETAA
>NZ_CP046115.1|WP_004130898.1|1935427_1935745_+|ATP-dependent-Clp-protease-adapter-ClpS
MSKRDWLDFDQLVEDEVKDALKPPSMYKVILVNDDYTPMEFVIDVLQKFFSYDVERATQLMLTVHYQGKAICGVFTAEVAETKVSMVNQYARENEHPLLCTLEKA
>NZ_CP046115.1|WP_154679883.1|1935775_1938058_+|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA
MLNQELELSLNMAFARAREHRHEFMTVEHLLLALLSNPSAREALEACSVDLVALRQELEAFIEQTTPVLPTTEEDRDTQPTLSFQRVLQRAVFHVQSSGRSEVTGANVLVAIFSEQESQAAYLLRKHEVSRLDVVNFISHGTRKDEPSQSSDNSGSQPGSSEEQAGGEDRMENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGVGKTAIAEGLAWRIVQGDVPEVMADCTIYSLDIGSLLAGTKYRGDFEKRFKALLKQLEQDTNSILFIDEIHTIIGAGAASGGQVDAANLIKPLLSSGKIRVIGSTTYQEFSNIFEKDRALARRFQKIDITEPSVEETVQIINGLKPKYEAHHDVRYTAKAVRAAVELAVKYINDRHLPDKAIDVIDEAGARARLMPVSKRKKTVNVADIESVVARIARIPEKSVSRSDRDTLKNLGDRLKMLVFGQDKAIEALTEAIKMARAGLGHEHKPVGSFLFAGPTGVGKTEVTVQLAKSLGIELLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAVLLLDEIEKAHPDVFNLLLQVMDNGTLTDNNGRKADFRNVVLVMTTNAGVRETERKSIGLIHQDNSPDAMDEIKKIFTPEFRNRLDNIIWFDHLSTTVIHQVVDKFIVELQVQLDQKGVSLEVSQEARDWLAEKGYDRAMGARPMARVIQDNLKKPLANELLFGSLVDGGQVTVELDKEKNALTYDFQSAQKHKPEAAH

Crispr_ID: NZ_CP046115_2

• CRISPR_ID: NZ_CP046115_2
• CRISPR_location: 3614350-3614744
• CRISPR_type: Orphan
• Repeat_type: I-E
• Spacer_info: 6 spacers

Consensus repeat of NZ_CP046115_2

Consensus_repeat	Method
CGGTTTATCCCCGCTCACGCGGGGAACAC	CRISPRCasFinder
CGGTTTATCCCCGCTCACGCGGGGAACAC	CRT
CGGTTTATCCCCGCTCACGCGGGGAACAC	PILER-CR

spacers of NZ_CP046115_2

>2.1|3614379|32|NZ_CP046115|CRISPRCasFinder,CRT
GTCTTCAGACCAGGCGAGCATATCCAGAAACG
>2.2|3614440|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR
GGATACAGCGCTAATCTGATCGAATCGGGGAC
>2.3|3614501|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR
GCCGTGGGCTAACCGTGCCTGCAGTTTTGAAT
>2.4|3614562|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR
TCCTGGAATACGAACGTTTCCAGATCTGAGCG
>2.5|3614623|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR
TTCTGCATAGGTTTCTAAGTTCGCCCGGTACT
>2.6|3614684|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR
TGGAAATAACTATCCAGAACATGCGCATCGAC

CRISPR arrays and Neighbor proteins around NZ_CP046115_2

CRISPR arrays

The CRISPR arrays of NZ_CP046115_2

>merge|NZ_CP046115|2|3614350-3614744|CRISPRCasFinder,CRT,PILER-CR
TAGGTTCTCCCCGCTTACGCGGGGAACACGTCTTCAGACCAGGCGAGCATATCCAGAAACGCGGTTTATCCCCGCTCGCGCGGGGAACACGGATACAGCGCTAATCTGATCGAATCGGGGACCGGTTTATCCCCGCTCACGCGGGGAACACGCCGTGGGCTAACCGTGCCTGCAGTTTTGAATCGGTTTATCCCCGCTCACGCGGGGAACACTCCTGGAATACGAACGTTTCCAGATCTGAGCGCGGTTTATCCCCGCTCACGCGGGGAACACTTCTGCATAGGTTTCTAAGTTCGCCCGGTACTCGGTTTATCCCCGCTCACGCGGGGAACACTGGAAATAACTATCCAGAACATGCGCATCGACCGGTTTATCCCCGCTCACGCGGGGAACAC

>NZ_CP046115|2|2|3614350-3614744|CRISPRCasFinder
TAGGTTCTCCCCGCTTACGCGGGGAACAC	GTCTTCAGACCAGGCGAGCATATCCAGAAACG
CGGTTTATCCCCGCTCGCGCGGGGAACAC	GGATACAGCGCTAATCTGATCGAATCGGGGAC
CGGTTTATCCCCGCTCACGCGGGGAACAC	GCCGTGGGCTAACCGTGCCTGCAGTTTTGAAT
CGGTTTATCCCCGCTCACGCGGGGAACAC	TCCTGGAATACGAACGTTTCCAGATCTGAGCG
CGGTTTATCCCCGCTCACGCGGGGAACAC	TTCTGCATAGGTTTCTAAGTTCGCCCGGTACT
CGGTTTATCCCCGCTCACGCGGGGAACAC	TGGAAATAACTATCCAGAACATGCGCATCGAC
CGGTTTATCCCCGCTCACGCGGGGAACAC

>NZ_CP046115|2|1|3614350-3614744|CRT
TAGGTTCTCCCCGCTTACGCGGGGAACAC	GTCTTCAGACCAGGCGAGCATATCCAGAAACG
CGGTTTATCCCCGCTCGCGCGGGGAACAC	GGATACAGCGCTAATCTGATCGAATCGGGGAC
CGGTTTATCCCCGCTCACGCGGGGAACAC	GCCGTGGGCTAACCGTGCCTGCAGTTTTGAAT
CGGTTTATCCCCGCTCACGCGGGGAACAC	TCCTGGAATACGAACGTTTCCAGATCTGAGCG
CGGTTTATCCCCGCTCACGCGGGGAACAC	TTCTGCATAGGTTTCTAAGTTCGCCCGGTACT
CGGTTTATCCCCGCTCACGCGGGGAACAC	TGGAAATAACTATCCAGAACATGCGCATCGAC
CGGTTTATCCCCGCTCACGCGGGGAACAC

>NZ_CP046115|2|2|3614411-3614744|PILER-CR
CGGTTTATCCCCGCTCGCGCGGGGAACAC	GGATACAGCGCTAATCTGATCGAATCGGGGAC
CGGTTTATCCCCGCTCACGCGGGGAACAC	GCCGTGGGCTAACCGTGCCTGCAGTTTTGAAT
CGGTTTATCCCCGCTCACGCGGGGAACAC	TCCTGGAATACGAACGTTTCCAGATCTGAGCG
CGGTTTATCCCCGCTCACGCGGGGAACAC	TTCTGCATAGGTTTCTAAGTTCGCCCGGTACT
CGGTTTATCCCCGCTCACGCGGGGAACAC	TGGAAATAACTATCCAGAACATGCGCATCGAC
CGGTTTATCCCCGCTCACGCGGGGAACAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046115.1|WP_154682757.1|3607316_3608045_+|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|226674
NZ_CP046115.1|WP_154681220.1|3608075_3609683_+|ribulokinase	unknown	unknown	gnl|CDD|212663
NZ_CP046115.1|WP_154681227.1|3620338_3620656_+|nickel/cobalt-homeostasis-protein-RcnB	unknown	unknown	gnl|CDD|227742
NZ_CP046115.1|WP_154681225.1|3615967_3617788_+|amidohydrolase-family-protein	unknown	unknown	gnl|CDD|223933
NZ_CP046115.1|WP_154681226.1|3617790_3619134_+|NCS2-family-permease	unknown	unknown	gnl|CDD|225161
NZ_CP046115.1|WP_154681231.1|3629202_3630291_+|AAA-domain-containing-protein	unknown	unknown	gnl|CDD|223786
NZ_CP046115.1|WP_154681217.1|3603499_3604867_-|mannitol-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|223324
NZ_CP046115.1|WP_154681222.1|3611112_3612165_-|class-I-fructose-bisphosphate-aldolase	unknown	unknown	gnl|CDD|236431
NZ_CP046115.1|WP_154681223.1|3612313_3613114_-|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase	unknown	unknown	gnl|CDD|180561
NZ_CP046115.1|WP_154681229.1|3622658_3624692_+|methionine--tRNA-ligase	unknown	unknown	gnl|CDD|234655
NZ_CP046115.1|WP_154682758.1|3614920_3615844_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223656
NZ_CP046115.1|WP_154681230.1|3624834_3628572_+|DUF4132-domain-containing-protein	unknown	unknown	gnl|CDD|379270
NZ_CP046115.1|WP_154681228.1|3621397_3622507_-|iron-sulfur-cluster-carrier-protein-ApbC	unknown	unknown	gnl|CDD|183270
NZ_CP046115.1|WP_154682760.1|3620715_3621045_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046115.1|WP_154681219.1|3606036_3607038_-|substrate-binding-domain-containing-protein	unknown	unknown	gnl|CDD|380498
NZ_CP046115.1|WP_154682759.1|3619254_3620169_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176114
NZ_CP046115.1|WP_154681216.1|3602026_3603490_-|xylulokinase	unknown	unknown	gnl|CDD|198374
NZ_CP046115.1|WP_154681224.1|3613110_3613884_-|hydroxyethylthiazole-kinase	unknown	unknown	gnl|CDD|236477
NZ_CP046115.1|WP_154681218.1|3605073_3606015_+|cytochrome-C-biogenesis-protein-CcdA	unknown	unknown	gnl|CDD|367868
NZ_CP046115.1|WP_154681221.1|3609765_3611049_+|MFS-transporter	unknown	unknown	gnl|CDD|162096

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046115.1|WP_154682757.1|3607316_3608045_+|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|226674	COG4221, COG4221, Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only].	1.09397e-74
NZ_CP046115.1|WP_154681220.1|3608075_3609683_+|ribulokinase	gnl|CDD|212663	cd07782, FGGY_YpCarbK_like, Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases. This subgroup is composed of the uncharacterized Yersinia Pseudotuberculosis carbohydrate kinase that has been named glyerol/xylulose kinase and similar uncharacterized proteins from bacteria and eukaryota. Carbohydrate kinases catalyze the ATP-dependent phosphorylation of their carbohydrate substrate to produce phosphorylated sugar and ADP. The presence of Mg2+ is required for catalytic activity. This subgroup shows high homology to characterized ribulokinases and belongs to the FGGY family of carbohydrate kinases, the monomers of which contain two large domains, which are separated by a deep cleft that forms the active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain.	0
NZ_CP046115.1|WP_154681227.1|3620338_3620656_+|nickel/cobalt-homeostasis-protein-RcnB	gnl|CDD|227742	COG5455, COG5455, Predicted integral membrane protein [Function unknown].	7.47388e-23
NZ_CP046115.1|WP_154681225.1|3615967_3617788_+|amidohydrolase-family-protein	gnl|CDD|223933	COG1001, AdeC, Adenine deaminase [Nucleotide transport and metabolism].	0
NZ_CP046115.1|WP_154681226.1|3617790_3619134_+|NCS2-family-permease	gnl|CDD|225161	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism].	3.08155e-116
NZ_CP046115.1|WP_154681231.1|3629202_3630291_+|AAA-domain-containing-protein	gnl|CDD|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	3.85496e-40
NZ_CP046115.1|WP_154681217.1|3603499_3604867_-|mannitol-dehydrogenase-family-protein	gnl|CDD|223324	COG0246, MtlD, Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism].	2.64106e-135
NZ_CP046115.1|WP_154681222.1|3611112_3612165_-|class-I-fructose-bisphosphate-aldolase	gnl|CDD|236431	PRK09250, PRK09250, class I fructose-bisphosphate aldolase.	0
NZ_CP046115.1|WP_154681223.1|3612313_3613114_-|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase	gnl|CDD|180561	PRK06427, PRK06427, bifunctional hydroxy-methylpyrimidine kinase/ hydroxy-phosphomethylpyrimidine kinase; Reviewed.	1.57174e-159
NZ_CP046115.1|WP_154681229.1|3622658_3624692_+|methionine--tRNA-ligase	gnl|CDD|234655	PRK00133, metG, methionyl-tRNA synthetase; Reviewed.	0
NZ_CP046115.1|WP_154682758.1|3614920_3615844_-|LysR-family-transcriptional-regulator	gnl|CDD|223656	COG0583, LysR, Transcriptional regulator [Transcription].	4.01166e-39
NZ_CP046115.1|WP_154681230.1|3624834_3628572_+|DUF4132-domain-containing-protein	gnl|CDD|379270	pfam13569, DUF4132, Domain of unknown function (DUF4132). This domain might be involved in the biosynthesis of the molybdopterin cofactor in E.coli.	4.62436e-62
NZ_CP046115.1|WP_154681228.1|3621397_3622507_-|iron-sulfur-cluster-carrier-protein-ApbC	gnl|CDD|183270	PRK11670, PRK11670, iron-sulfur cluster carrier protein ApbC.	0
NZ_CP046115.1|WP_154681219.1|3606036_3607038_-|substrate-binding-domain-containing-protein	gnl|CDD|380498	cd06274, PBP1_FruR, ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs. Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs, all of which are members of the LacI-GalR family of bacterial transcription regulators. The LacI-GalR family repressors are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to members of the type 1 periplasmic binding protein superfamily. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding affinity of the repressor.	6.76579e-107
NZ_CP046115.1|WP_154682759.1|3619254_3620169_-|LysR-family-transcriptional-regulator	gnl|CDD|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.15402e-63
NZ_CP046115.1|WP_154681216.1|3602026_3603490_-|xylulokinase	gnl|CDD|198374	cd07808, FGGY_D-XK_EcXK-like, Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases. This subgroup is predominantly composed of bacterial D-xylulose kinases (XK, also known as xylulokinase; EC 2.7.1.17), which catalyze the rate-limiting step in the ATP-dependent phosphorylation of D-xylulose to produce D-xylulose 5-phosphate (X5P) and ADP. D-xylulose has been used as a source of carbon and energy by a variety of microorganisms. Some uncharacterized sequences are also included in this subgroup. The prototypical member of this CD is Escherichia coli xylulokinase (EcXK), which exists as a dimer. Each monomer consists of two large domains separated by an open cleft that forms an active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain. The presence of Mg2+ or Mn2+ is required for catalytic activity. Members of this subgroup belong to the FGGY family of carbohydrate kinases.	0
NZ_CP046115.1|WP_154681224.1|3613110_3613884_-|hydroxyethylthiazole-kinase	gnl|CDD|236477	PRK09355, PRK09355, hydroxyethylthiazole kinase; Validated.	1.38581e-117
NZ_CP046115.1|WP_154681218.1|3605073_3606015_+|cytochrome-C-biogenesis-protein-CcdA	gnl|CDD|367868	pfam04198, Sugar-bind, Putative sugar-binding domain. This probable domain is found in bacterial transcriptional regulators such as DeoR and SorC. These proteins have an amino-terminal helix-turn-helix pfam00325 that binds to DNA. This domain is probably the ligand regulator binding region. SorC is regulated by sorbose and other members of this family are likely to be regulated by other sugar substrates.	3.48606e-89
NZ_CP046115.1|WP_154681221.1|3609765_3611049_+|MFS-transporter	gnl|CDD|162096	TIGR00897, Alpha-ketoglutarate_permease, polyol permease family. This family of proteins includes the ribitol and D-arabinitol transporters from Klebsiella pneumoniae and the alpha-ketoglutarate permease from Bacillus subtilis. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	0

Protein sequences

>NZ_CP046115.1|WP_154681224.1|3613110_3613884_-|hydroxyethylthiazole-kinase
MSDLLNPAHIAHLRHLFHRHSPLVHCMTNDVVQTFTANVLLALGASPAMVIDADEAKQFAAVADALLINVGTLTVERAAAMRAAVQSAQEAGKPWALDPVAIGALSLRTEFCRELLALQPAAIRGNASEIMALAGMSGGGRGVDTTDTAVAALPAAQALARQLNTVVAVTGEVDYVTDGQRTRMVTGGDLLMTRVVGTGCALSAVVAAAAAMPGDRLENIAAACGLMKLAGGKAAQRGGPGSFIPAFLDALYAGGDL
>NZ_CP046115.1|WP_154681223.1|3612313_3613114_-|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase
MKRINALTIAGTDPSGGAGIQADLKTFSALGAYGCSVITALVAQNTRGVQSVYRIEPDFVAAQLDSVFSDVRIDTTKIGMLAETDIVEAVAERLARYQIKNVVLDTVMLAKSGDPLLSVSAIQTLRQRLLPQVSLITPNLPEAAALLDAPHARTEQEMLEQGRALLGMGCGAVLMKGGHLDDAESPDWLFTREEELRFTAPRVQTKNTHGTGCTLSAALAALRPRYDGWGQTVAEAKGWLSAALAQADSLEVGHGIGPVHHFHAWW
>NZ_CP046115.1|WP_154681222.1|3611112_3612165_-|class-I-fructose-bisphosphate-aldolase
MTDITQLLGKDADTLLQHRCMTIPADQLYLPGSDYVDRVMVDNNRPPAVLRNMQTLYNTGRLAGTGYLSILPVDQGVEHSAGASFAANPLYFDPKNIVELAIEAGCNCVASTYGVLASVSRRYAHRIPFLVKLNHNETLSYPTEYDQTLYASVEQAFNMGAVAVGATIYFGSEQSRRQIEEISAAFERAHELGLVTVLWAYLRNPAFKKDGVDYHVSADLTGQANHLAATIGADIVKQKMAENNGGYKAVNFGYTDDRVYSKLTSDNPIDLVRYQLANCYMGRAGLINSGGAAGGETDLSDAVRTAVINKRAGGMGLILGRKAFKKSMADGVKLINAVQDVYLDGKVTIA
>NZ_CP046115.1|WP_154681221.1|3609765_3611049_+|MFS-transporter
MSINNKQWFGLPLNLIWGYVAIAVFMTGDGFELAFLSHYIKELGFTPAQASFAFTLYGLAAALSAWVSGVVAEIITPRKTMMIGFVLWCVFHVLFLVFGLGRANYALILLFYGIRGLAYPLFLYSFIVAIIHNVRSDSSSSALGWFWAVYSVGIGVFGSYIPSFTIPHIGEMGTLWLALVFCATGGIIALVSMRNTETPRHMQNLTTREKFSELGRAVTLIYTNRSILFSSIVRIINTLSLFGFAVIMPMMFVDELGFTTSEWLQVWAAFFFTTIFSNVFWGIVAEKMGWMKVIRWFGCIGMALSSLAFYYLPQHFGHNFAMALVPAIALGIFVAAFVPMAAVFPALEPNHKGAAISVYNLSAGLSNFLAPAIAVVLLPYFSTIGVVIAYTALYILAFFLCPLIRVEQPGFTTAQDAEPLTANVAES
>NZ_CP046115.1|WP_154681220.1|3608075_3609683_+|ribulokinase
MQSDNQNIIGVDVGSGSVRAGVFNLQGELLAHATREITLFRSAGSVVEQSSREIWQAVCYCIKTAVANASVEPSSIAGIGFDATCSLVVVGENNAPLAVGPSEDPDRNIIVWMDHRATGQAEKINATGHPVLQYVGGKISPEMETPKILWLKENRPHIYQQAHHFFDLADYLTWRSTGDLARSVCTVTCKWTYLAHEKRWDAGYFRQIGLEELAEEDFVRIGQRIVDPGTPCGDGLCAAAAAEMGLPVGTPVAVGMIDAHAGGIGTVGVLNGAVNNMAYVFGTSSCTMTTTQEAVFVPGVWGPYYSAMVPGYWLNEGGQSAAGAAIDQLLSFHPAAAEAREQAKAAGLPLPVWLADRVLAQVASPSEAVTLAAGLHVVPEFLGNRAPLADPHAKALIAGLGMERDLDNLTALYVAGLCGIGYGLRQILDAQRACGIESENIVISGGAGQHPLVRQLLADACGVTVVSTASSEPVLLGSAILGAVAGKVAASLPEAMKQFTKVDTTYHSETAFSPLHQRRYEAYKALQQAGRLIRE
>NZ_CP046115.1|WP_154682757.1|3607316_3608045_+|SDR-family-NAD(P)-dependent-oxidoreductase
MNTSLNGKVAAITGAASGIGLECAKTLLGAGAKVVLIDREGEKLNKIVAELGENAFALQVDLMQADQVDNILQGILNLTGRLDIFHANAGAYIGGPVAEGDPDVWDRVLHLNTNAAFRCVRSVLPHLIAQKSGDIIFTSSIAGVVPVIWEPIYTASKFAVQAFVHTTRRQVSQYGVRVGAVLPGPVVTALLDDWPKAKMDEALANGSLMQPIEVAESVLFMVTRSKNVTVRDIVILPNSVDL
>NZ_CP046115.1|WP_154681219.1|3606036_3607038_-|substrate-binding-domain-containing-protein
MKKITIYDLAELSGVSASAVSAILNGNWKKRRISAKLAEKVTRIAEEQGYAINRQASMLRSKKSHVIGMIVPKYDNRYFGSVAERFEEMARERGLLPIITCTRRSPELEIEAVKAMLSWQVDWVVATGATNPDKITALCQQAGVPVVNLDLPGSIAPSVISDNYGGAKALTLKILANSAGRRGKLAPLTFIGGRSSDHNTAERLRGFHDAHREQGLSVPQENILAPGYSKGKVEACLQERFGTAQTQLQGVFVNSTISLEGVVRWLSQAGLTGSEQPPMGCFDWDPFVYLLGHDIDMVQQDVPAMLEAVFQIIDSGDASPQRIEIPPLLMSSR
>NZ_CP046115.1|WP_154681218.1|3605073_3606015_+|cytochrome-C-biogenesis-protein-CcdA
MSKEDDIRMDQKVRAAWMYYIAGQNQSEIASQLGTSRPVVQRLIAAAKEEGIVSISLHHPVANCLDYAQLLQEKYQLIECNIVPAFSDESTLDSVSFGCYQLMARYLQDDNEKIIGLGSGLTLKKALQRIDFDSLNTRCVALISAMDADGQCNYYDDVPLLLTSKIKAKYYQWPAPRYAQTQDEHNMWCTSRLFRSVSAVARRADVIFVGIGPLGTQSPIFKDGFINQAQMDELTARGGIGEIMGRFIDAEGGVVDSEINRMITSYDIRQNACPRIAVACGEYKRPAILAALKGGWINGLVTDEHTARWLLTR
>NZ_CP046115.1|WP_154681217.1|3603499_3604867_-|mannitol-dehydrogenase-family-protein
MNNQFTWLHIGLGSFHRAHQAWYLHRLIASGDRRWHIAAGNIRNDAEQVVQALAAQGGRYVLETVSPEGEREYEEITSIQKLLPWQAGLQPLINEGANPQTKVIAFTVTEGGYYLNTSHKLETSNPDLQADLQGECKTIYGTIARILEKRMADNAGPLTLLNCDNVRHNGERFHDGMVEFLQLTGKQAVIDWMAANTTCPNTMVDRITPRPAADLPARIKAQTGIDDKAPVMGETFIQWVVENKFRDERPNLEAVGVEMVESVIPYEEAKIRILNSSHSCIAWAGTLIGQQYIHESTLTDFIYAIADRYVTEDVIPCLGDNGIDLPTYRDVVLKRFTNPYIQDTNQRVAADGFSKIPAMIAPTLQECYQRGVRPQATAMLPALFFVFMEQWHKGTLPYQYQDGILDAQAVHEMFESSDPVALYARDKALFGTLADNADFLALMREKVAAVYALIK
>NZ_CP046115.1|WP_154681216.1|3602026_3603490_-|xylulokinase
MYLGIDLGTSEVKALVIDENNEVIASHSAPLSIQRPHPHWSEQSPQSWWEATEYLMTTLREKCAQHWPAIKAIGLSGQMHGAVLLDAAGEVIRPAILWNDTRCAGECDELEDMAPELHQVAGNLAMPGFTAPKLLWVRRHEPQNFQRTATVLLPKDYLRYRMTGKKVSDMSDAAGTLWLDVAKRDWSDSLLDKCGLSRSHMPSLVEGCEVSATLDPQVAERWGLNASVVVAGGGGDNAVSAIGVGAVSPGDAFISLGTSGVLFVVTDAYRPAPQSAVHAFCHVLPNLWHQMSVMLSAASCLQWFCRLTGTTEVALLEEIAELSEEEKAHAPFFLPYLSGERTPHNDPDARGMFWGMTHSSLRAQLGYAVLEGVSFGINDGLRVLKETGTQIEQCSLVGGGARSPFWAQLLADILDMPVVTHKGGETGGALGAARLACLAAGKPVAAVCEKPEVWQTWRADPLRHQTLMQRYAQFNALYLNDLNYRQH
>NZ_CP046115.1|WP_154682758.1|3614920_3615844_-|LysR-family-transcriptional-regulator
MTEPWQRLPALSLKQIQYFVTLAQLRHFTDTANRLAISQPALSSALRQIETVLGGKLVNRTASAVTLTELGAAILPHAQRVLSVAQLAFQDMQQIVEAGGDGTVRIGLVPSVSSLLFPLLPQTLAQAFPRLRVEFHDQTNDALFCELQSGKIDFAVGAIDNSLPPELQVYPLREDPFVAVLHCDDPLAGQPHLPWKLLAGRDIAVFSKGNIQRLVGALAESHRLTLKTRYQVDYIETLYGLVRSRLAVAILPELYTTHLQDPALKIAQLQQPALTRTVALMRGPQPLPPLIEACFALLLGALREVNL
>NZ_CP046115.1|WP_154681225.1|3615967_3617788_+|amidohydrolase-family-protein
MSSSAETRRRAVQAARGESPFDLLLTDAQIVDMATGEIRAADVGIVGETIASVHPRGSRSDAHERRSLAGCFLSPGLMDTHVHLESSHLPPERYAEIVLAQGTTAVFWDPHELANVLGVEGVRYAVAASRNLPLQVMVAAPSSVPSTPGLEMSGADFAGAEMATMLAWPEVCGVAEVMDMHGVLHGSERMQEIIQAGLDSGKLIEGHARGLSGADLQAYLAAGVTSDHELTSAEDALEKLRAGLTIEIRGSHPYLLPDIVNALKTLPHLSSQITVCTDDVPPDMLLEKGGIIALLNQLIEHGLPATDVLRFATLNAAIRLQRNDLGLIAAGRRADLVVFDSLEKLNAREVFVAGKLIARDGTLLQPVPAATGVIPPRDTLQMGRLSPDDFILRVGAIRHGLARLRHIRGARFTQWGEVEVQVRDGKVQVPDGFSLIWVKHRHGRHEAKPQIALLEGWGELRGAIATSYSHDSHNLVVLGRDAEDMALAANRLLDSGGGMALSQQGKILAHVAMPIAGMLSDLPAPELARQFRQLRDLSAEVADWEPPYRVFKAIEGTCLACNAGPHLTDLGLTDGSTRQIVEPLIDCREIPEHTEHTEHNNKHQGA
>NZ_CP046115.1|WP_154681226.1|3617790_3619134_+|NCS2-family-permease
MADNTLNSSAQGSWLERRFALYSRGSTLRTECLAGVTGFLAAAYLLVVIPGLLAVGGMDKGAATTGTILVFVGGTLLMAFYANLPFIVGPGIGGSVLVGVTLAGSEGIGWQVGLGIACWSGILFFLLTKFGLREVVTRSVPQSIKLGLTASIGLFVAVLGFRNAGLVLANAKTNALMLGDFLSPGALVALCGLFLAIALQARKIPGSILWAILFATLVGIPMGVTKLPGSFIDMPHSLTPVLGQIDMLGALNIAFLPFLFVFFASEFFSTMGTTLAVGGEAGLLDEEGNMPHINRPFMVDSIAAAVGPWLGIPAATALIESSAAAEAGGKTGLTALSAAVMFLLMLLFTPIALMIPKEATAPALILIGLNMFSGLRKVDLANFTDGLPVLMMVMITLIANSFGTGIAGGLLFYVVIKTIAGKWREIPIGLWILAIPLVYYFATLVKH
>NZ_CP046115.1|WP_154682759.1|3619254_3620169_-|LysR-family-transcriptional-regulator
MFRLEDLALFVRAAALSSFSEAAREAGQQPAQVSAAIKRLETTLNIRLFARSTRSLRLTQEGETWLPYATQMLDTLHAGLQKIHTPDDEVRGTLQIAVPSDLGRNLLLRVFRDFRQRYPGLRLRILFSDHRTDVFKDPVDIAFRYGDNDDASFISLPVAPENRRVLVASPAWIAEHGEPQTLEDLSRHNALIYLLRGRAFDRWPLSLEGKVHYAQVSGPVVSDDAEVIRRLAVAGEGIAFKSELDVGDDLREGRLQILLPQYQGDVVPLNMICPHRKQLSPAVRLLYEAVKEACEAVSSRMALR
>NZ_CP046115.1|WP_154681227.1|3620338_3620656_+|nickel/cobalt-homeostasis-protein-RcnB
MRKTKMMLLGVLLACTSGAWAATGDGIQKYELDGVTADFKQFRIGDTVPPMYLTPEYNIKQWQQRNLPAPDAGTRWTYMGGSYVLITETEGKILKIYDGEIFYHR
>NZ_CP046115.1|WP_154682760.1|3620715_3621045_-|hypothetical-protein
MNNIALIAKLRELLVIFMHARTLPEKAADAMRYCQENISLTEIPIGACGEYREIFEQIVFLSQQNNRAAPDDLLRSGGDLILSILMLYEQVASYIAVEEFMQKQNRFNE
>NZ_CP046115.1|WP_154681228.1|3621397_3622507_-|iron-sulfur-cluster-carrier-protein-ApbC
MSSQSQAKSPERLRAMVAGTLANFQHPTLKHNLTTLKALHHVAWLDETVHIEIQMPFVWNSAFEVLKEQCSAELLRITGAKAIDWKLTHSIATLQRVKNQPGINGVKNIIAISSGKGGVGKSSTAVNLALALAAEGAKVGILDADIYGPSIPTMLGAEDQRPTSPDGTHMAPIMKFGLATNSIGYLVTDDNAMVWRGPMASKALMQMLQETLWPDLDYLVLDMPPGTGDIQLTLAQNIPVTGAVVVTTPQDIALIDAKKGIVMFEKVEVPVLGIVENMSMHICSNCGHHEPIFGTGGAQKLAEKYRTQLLGQLPLHITLREDLDKGTPTVVARPESEFTETYRLLADRVAAQLYWQGEVIPGEIAFRAV
>NZ_CP046115.1|WP_154681229.1|3622658_3624692_+|methionine--tRNA-ligase
MTQVAKKILVTCALPYANGSIHLGHMLEHIQADVWVRYQRMRGHEVNFICADDAHGTPIMLKAQQLGITPEQMIGEMSQEHQTDFAGFDISYDNYHSTHSDENRELSELIYTRLKENGFIKNRTISQLYDPEKGMFLPDRFVKGTCPKCKSPDQYGDNCEVCGATYSPTELIEPKSVVSGATPVMRDSEHFFFDLPSFSEMLQAWTRSGALQEQVANKMQEWFESGLQQWDISRDAPYFGFEIPDAPGKYFYVWLDAPIGYMGSFKNLCDKRGDTVSFDEYWKKDSTAELYHFIGKDIVYFHSLFWPAMLEGSSFRKPTNLFVHGYVTVNGAKMSKSRGTFIKASTWLKHFDADSLRYYYTAKLSSRIDDIDLNLEDFVQRVNADIVNKVVNLASRNAGFINKRFDGVLSAELADPALYKTFTDAAASIGEAWDSREFGKAIREIMALADVANRYVDEQAPWVVAKQEGRDADLQAICTMGLNMFRVLMTWLKPVLPQLAARAEAFLNGELSWDAIQQPLLGHRVNTFKALYNRLEMKQVEALVEASKEEVKALSAPVTGPLADDPIQETITFDDFAKVDMRIALIENAEFVDGSDKLLRLTLDLGGEKRNVFSGIRSAYPDPQALIGRLTVMVANLAPRKMRFGISEGMVMAAGPGGKDIFLLSPDSGAQPGQQVK
>NZ_CP046115.1|WP_154681230.1|3624834_3628572_+|DUF4132-domain-containing-protein
MKTFIYHDEKSHKFWAVEQQSSELHLSWGKVGTHGQSQIKTFADAAAASKAEQKLINEKTRKGYVEDTAAAQPAAASPPAEIASPAAAPQPNSSPAPAGIIRPWLADDAELALSDELLQEALPSRLYPGEAIAAPEESKLMDLGKEIHQQSGKVVTFSYADCSAYWQQIINEALTDGQLSPAALAVQVAVTTRRGWYRDDNSGLMDEIVYVYGLEYATEVFIALQHIEFDYNYQTVQVTFRSQPTDARGPSMLDIRLRAHLALADEALWQRCVDKLISALPDMPIGQQPLVALLLPERQDIVNDIAQRVLAHKNVKTAEWLKLVARDPQVVNALEPYRAENLFNDYYHGSVWNVTVMREQGVAGIARFAPYVQDDLCGDLVSNVNHPQALMQLIRVSEQGKRCHERMSRASARFPHAALAALAELLVQKEEKRWRIMLMTLLSAQPELAAQISPWLSAQAASLLNACQQQLNQQTDCAGADILPLLLLSPPWAAKKKKPSVPQLSLTPLALEPVCMLTEEAAKALLAQRSWYASQVEMGKQEDEKEYLTRLGFRSWSHKNDRYEKASDLVVDAWQRQDYPALIAEFKAYHSPSPGEWKLYMLASLPAERAAQAWNTLSKEPHTGAEYVMSYLRLAGLPGFVNALSRYPQENLSVAIWFAASELAPVVARAFNKLKSLREVAREWLLTYPEHAITGLLPAALGKAGEAQDSARLAIRLLIDNGHQPLLEQVSRRYNQPEVMEAVSALLALDPLDNHPTKIPPLPAFYQPALWTRPLLREQGLALPNEALKTLGEMLRFPTDESIYPGLQLVKELCTAESLAAFAWDLFSAWQTAGAPSKESWAFTALGLFGNDDTARALTPLIRAWPGESQHKRATVGLDILTAIGTDIALMQLNGIAQKLKFKALQERAREKIGDIAESRELTVEELEDRLAPDLGLNDDGTLTLDFGPRHFVVSFDEALKPYVRDENGSRLKDLPKPNKSDDNALATDAVNRYKALKKDARTIAAQQIARMESAMCQRRRWTAKNFHQFLVAHPLVRHLTRRLVWGVYGADNTLLACFRVAEDNSYSTADDDLFTLPQGDIRIGLPHLLEMPAQDAAAFGQLFADYELLPPFRQLDRNCYTLTPAELSATELTRWAGRKCPSGRVIGLANKGWLRGEPQDGGWIGWMLKPLGEWALVMEIDEGFAVGLLPDELSAEQLLSKVWLYAGKAHQYGWGGNAPQQATFSVLDSVTISELINDIDGLFE
>NZ_CP046115.1|WP_154681231.1|3629202_3630291_+|AAA-domain-containing-protein
MTQQEKHLQRPPAAVLYADELARLRQDDPHPCPPGWQLSLPAARAFILGDSARDISRKVVISPAAVERMLVTLATGRGLMLVGEPGTAKSLLSELLATAICGDAGLTIQGGAAITEDQIKYAWNYALLINQGPSAQALVPAPLYQGMRDGKIVRFEEITRTPLEVQDCLLGMLSDRVMAIPELTGDDSLLYARAGFNIIATANTRDRGVNEMSAALKRRFDFETVFPIMDFQQELELVANASARLLEHSGIPHKVPDAILELLVQTFRDLRADGGKKTTMDTLNAIMSTAEAVNVAHAVGVRAWFLAGRAGEPADLVDCIAGTIVKDNEDDRARLRRYFEQRVGTHKEAHWQAYYQARHRLP

Crispr_ID: NZ_CP046115_3

• CRISPR_ID: NZ_CP046115_3
• CRISPR_location: 3903619-3903692
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP046115_3

Consensus_repeat	Method
CTCACCAACAACGCCGATCGTTCC	CRISPRCasFinder

spacers of NZ_CP046115_3

>3.1|3903643|26|NZ_CP046115|CRISPRCasFinder
GCCTGCCGCGCCGAGGAGAAACTGTA

CRISPR arrays and Neighbor proteins around NZ_CP046115_3

CRISPR arrays

The CRISPR arrays of NZ_CP046115_3

>merge|NZ_CP046115|3|3903619-3903692|CRISPRCasFinder
CTCACCAACAACGCCGATCGTTCCGCCTGCCGCGCCGAGGAGAAACTGTACTCACCAACAACGCCGATCGATCC

>NZ_CP046115|3|3|3903619-3903692|CRISPRCasFinder
CTCACCAACAACGCCGATCGTTCC	GCCTGCCGCGCCGAGGAGAAACTGTA
CTCACCAACAACGCCGATCGATCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046115.1|WP_154681438.1|3895907_3897206_+|transcriptional-regulator-PtsJ	unknown	unknown	gnl|CDD|185378
NZ_CP046115.1|WP_154681450.1|3906436_3907312_+|N-acetylmuramoyl-L-alanine-amidase-AmiA	unknown	unknown	gnl|CDD|182376
NZ_CP046115.1|WP_154681453.1|3909335_3909818_-|ethanolamine-utilization-microcompartment-protein-EutK	unknown	unknown	gnl|CDD|185363
NZ_CP046115.1|WP_154682769.1|3910498_3911386_-|ethanolamine-ammonia-lyase-subunit-EutC	unknown	unknown	gnl|CDD|226752
NZ_CP046115.1|WP_154681444.1|3901174_3902008_-|sulfate/thiosulfate-ABC-transporter-permease-CysT	unknown	unknown	gnl|CDD|182873
NZ_CP046115.1|WP_004104360.1|3905799_3906225_-|GNAT-family-acetyltransferase	unknown	unknown	gnl|CDD|235142
NZ_CP046115.1|WP_154681447.1|3903733_3904633_-|Dyp-type-peroxidase	unknown	unknown	gnl|CDD|367887
NZ_CP046115.1|WP_154681440.1|3897763_3898171_+|DUF4440-domain-containing-protein	unknown	unknown	gnl|CDD|226769
NZ_CP046115.1|WP_154681441.1|3898167_3899079_-|cysteine-synthase-CysM	unknown	unknown	gnl|CDD|236972
NZ_CP046115.1|WP_154681451.1|3907311_3908211_+|oxygen-dependent-coproporphyrinogen-oxidase	unknown	unknown	gnl|CDD|235413
NZ_CP046115.1|WP_154681452.1|3908234_3909287_-|HTH-type-transcriptional-regulator-EutR	unknown	unknown	gnl|CDD|182258
NZ_CP046115.1|WP_154681449.1|3905363_3905813_-|DUF2919-family-protein	unknown	unknown	gnl|CDD|378569
NZ_CP046115.1|WP_154681446.1|3903224_3903587_+|DUF559-domain-containing-protein	unknown	unknown	gnl|CDD|238509
NZ_CP046115.1|WP_154681443.1|3900299_3901175_-|sulfate/thiosulfate-ABC-transporter-permease-CysW	unknown	unknown	gnl|CDD|183225
NZ_CP046115.1|WP_154681442.1|3899215_3900310_-|sulfate/thiosulfate-ABC-transporter-ATP-binding-protein-CysA	unknown	unknown	gnl|CDD|182778
NZ_CP046115.1|WP_154681454.1|3909829_3910489_-|ethanolamine-utilization-microcompartment-protein-EutL	unknown	unknown	gnl|CDD|185303
NZ_CP046115.1|WP_154681445.1|3902007_3903024_-|sulfate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|236775
NZ_CP046115.1|WP_154681448.1|3904726_3905302_-|RpoE-regulated-lipoprotein	unknown	unknown	gnl|CDD|236742
NZ_CP046115.1|WP_154681437.1|3894958_3895825_-|pyridoxine/pyridoxal/pyridoxamine-kinase	unknown	unknown	gnl|CDD|181269
NZ_CP046115.1|WP_154681439.1|3897367_3897742_+|hypothetical-protein	unknown	unknown	gnl|CDD|236672

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046115.1|WP_154681438.1|3895907_3897206_+|transcriptional-regulator-PtsJ	gnl|CDD|185378	PRK15481, PRK15481, transcriptional regulatory protein PtsJ; Provisional.	0
NZ_CP046115.1|WP_154681450.1|3906436_3907312_+|N-acetylmuramoyl-L-alanine-amidase-AmiA	gnl|CDD|182376	PRK10319, PRK10319, N-acetylmuramoyl-L-alanine amidase AmiA.	0
NZ_CP046115.1|WP_154681453.1|3909335_3909818_-|ethanolamine-utilization-microcompartment-protein-EutK	gnl|CDD|185363	PRK15466, PRK15466, ethanolamine utilization microcompartment protein EutK.	1.58359e-90
NZ_CP046115.1|WP_154682769.1|3910498_3911386_-|ethanolamine-ammonia-lyase-subunit-EutC	gnl|CDD|226752	COG4302, EutC, Ethanolamine ammonia-lyase, small subunit [Amino acid transport and metabolism].	2.37433e-156
NZ_CP046115.1|WP_154681444.1|3901174_3902008_-|sulfate/thiosulfate-ABC-transporter-permease-CysT	gnl|CDD|182873	PRK10971, PRK10971, sulfate/thiosulfate ABC transporter permease CysT.	0
NZ_CP046115.1|WP_004104360.1|3905799_3906225_-|GNAT-family-acetyltransferase	gnl|CDD|235142	PRK03624, PRK03624, putative acetyltransferase; Provisional.	1.99328e-97
NZ_CP046115.1|WP_154681447.1|3903733_3904633_-|Dyp-type-peroxidase	gnl|CDD|367887	pfam04261, Dyp_perox, Dyp-type peroxidase family. This family of dye-decolourising peroxidases lack a typical heme-binding region.	6.52643e-133
NZ_CP046115.1|WP_154681440.1|3897763_3898171_+|DUF4440-domain-containing-protein	gnl|CDD|226769	COG4319, COG4319, Ketosteroid isomerase homolog [Function unknown].	3.27058e-30
NZ_CP046115.1|WP_154681441.1|3898167_3899079_-|cysteine-synthase-CysM	gnl|CDD|236972	PRK11761, cysM, cysteine synthase CysM.	0
NZ_CP046115.1|WP_154681451.1|3907311_3908211_+|oxygen-dependent-coproporphyrinogen-oxidase	gnl|CDD|235413	PRK05330, PRK05330, oxygen-dependent coproporphyrinogen oxidase.	0
NZ_CP046115.1|WP_154681452.1|3908234_3909287_-|HTH-type-transcriptional-regulator-EutR	gnl|CDD|182258	PRK10130, PRK10130, HTH-type transcriptional regulator EutR.	0
NZ_CP046115.1|WP_154681449.1|3905363_3905813_-|DUF2919-family-protein	gnl|CDD|378569	pfam11143, DUF2919, Protein of unknown function (DUF2919). This bacterial family of proteins has no known function. Some members are annotated as YfeZ however this cannot be confirmed.	2.82694e-44
NZ_CP046115.1|WP_154681446.1|3903224_3903587_+|DUF559-domain-containing-protein	gnl|CDD|238509	cd01038, Endonuclease_DUF559, Domain of unknown function, appears to be related to a diverse group of endonucleases.	1.12684e-46
NZ_CP046115.1|WP_154681443.1|3900299_3901175_-|sulfate/thiosulfate-ABC-transporter-permease-CysW	gnl|CDD|183225	PRK11602, cysW, sulfate/thiosulfate ABC transporter permease CysW.	0
NZ_CP046115.1|WP_154681442.1|3899215_3900310_-|sulfate/thiosulfate-ABC-transporter-ATP-binding-protein-CysA	gnl|CDD|182778	PRK10851, PRK10851, sulfate/thiosulfate ABC transporter ATP-binding protein CysA.	0
NZ_CP046115.1|WP_154681454.1|3909829_3910489_-|ethanolamine-utilization-microcompartment-protein-EutL	gnl|CDD|185303	PRK15405, PRK15405, ethanolamine utilization microcompartment protein EutL.	5.95236e-127
NZ_CP046115.1|WP_154681445.1|3902007_3903024_-|sulfate-ABC-transporter-substrate-binding-protein	gnl|CDD|236775	PRK10852, PRK10852, thiosulfate ABC transporter substrate-binding protein CysP.	0
NZ_CP046115.1|WP_154681448.1|3904726_3905302_-|RpoE-regulated-lipoprotein	gnl|CDD|236742	PRK10718, PRK10718, RpoE-regulated lipoprotein; Provisional.	1.96067e-129
NZ_CP046115.1|WP_154681437.1|3894958_3895825_-|pyridoxine/pyridoxal/pyridoxamine-kinase	gnl|CDD|181269	PRK08176, pdxK, pyridoxine/pyridoxal/pyridoxamine kinase.	6.52822e-179
NZ_CP046115.1|WP_154681439.1|3897367_3897742_+|hypothetical-protein	gnl|CDD|236672	PRK10318, PRK10318, hypothetical protein; Provisional.	1.58802e-56

Protein sequences

>NZ_CP046115.1|WP_154681446.1|3903224_3903587_+|DUF559-domain-containing-protein
MKNAQILARQLRRSLTPAERRLWYLLRDRRFARYKFRRQHPVGPYILDFACCSVRLAIELDGGRHDERSAYDARRTRWSQGQGWQVLRFWNNEFEHHEEAVMERILEALESPIPSPRPSP
>NZ_CP046115.1|WP_154681445.1|3902007_3903024_-|sulfate-ABC-transporter-substrate-binding-protein
MAVKSLKKGYLALAASVLLVAQAQATELLNSSYDVSRELFAALNPQFEQQWAKDNGGDKLTIKQSHAGSSKQALAILQGLKADVVTYNQVTDVQILHDKGKLIPADWQSRLPNNSSPFYSTMGFLVRKGNPKNIHDWNDLVRSDVKLIFPNPKTSGNARYTYLAAWGAADKADGGDNAKTEQFMTQFLKNVEVFDTGGRGATTTFAERGLGDVLISFESEVNNIRKQYEDQGFEVVIPKTNILAEFPVAWVDKNVQSNGTEKAAKAYLNWLYSPQAQTIITDYYYRVNNPQVMDSLKDKFPQTELFRVEDKFGSWPEVMKTHFASGGELDKLLAAGRR
>NZ_CP046115.1|WP_154681444.1|3901174_3902008_-|sulfate/thiosulfate-ABC-transporter-permease-CysT
MFAVASKRVLPGFTLSLGTSLLFVCLILLLPLSALVMQLSEMSWGQYWEVISNPQVVAAYKVTLLSAFVASIFNGVFGLLMAWILTRYRFPGRTLLDALMDLPFALPTAVAGLTLASLFSVNGFYGEWLAKFDIKVTYTWLGIAVAMAFTSIPFVVRTVQPVLEELGPEYEEAAETLGATRWQSFRKVVLPELSPALLAGIALSFTRSLGEFGAVIFIAGNIAWKTEVTSLMIFIRLQEFDYPAASAIASVILAASLLLLFSINTLQSRFGRRVVGH
>NZ_CP046115.1|WP_154681443.1|3900299_3901175_-|sulfate/thiosulfate-ABC-transporter-permease-CysW
MADVTELKRYDAPRINWGKWILIGIGMLVSAFILVVPMVYIFVHAFSKGLMPVLQNLADPDMLHAIWLTVMIALITVPVNLVFGTLLAWLVTRFTFPGRQLLLTLLDIPFAVSPVVAGLVYLLFYGSNGPLGGWLDEHNLQIMFAWPGMVLATIFVTCPFVVRELVPVMMSQGSNEDEAAILLGASGWQMFRRVTLPNIRWALLYGVVLTNARAIGEFGAVSVVSGSIRGETLSLPLQIELLEQDYNTVGSFTAAALLTLMAILTLFLKSVVQWRLANQEKRAQLEGNHEH
>NZ_CP046115.1|WP_154681442.1|3899215_3900310_-|sulfate/thiosulfate-ABC-transporter-ATP-binding-protein-CysA
MSIEIANIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLENQSSGHIRFHGTDVSRVHARDRKVGFVFQHYALFRHMTVFDNIAFGLTVLPRRERPNAAGIKAKVTKLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQILLLDEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEATEVADRVVVMSQGNIEQADAPDRVWREPATRFVLEFMGEVNRLKGTIRGGQFHVGAHRWPLGYTPAYQGSVDLFLRPWEVDISRRTSLDSPLPVQVLEASPKGHYTQLVVQPLGWYDEPLTVVHQGEEAPYRGERLFVGLQNARLYNGTERIEPREELALAESA
>NZ_CP046115.1|WP_154681441.1|3898167_3899079_-|cysteine-synthase-CysM
MNTLEQTIGNTPLVKLQRMGPDNGSEIWVKLEGNNPAGSVKDRAALSMIVEAEKRGEIKPGDVLIEATSGNTGIALAMIAALKGYQMKLLMPDNMSQERRAAMRAYGAELILVTKEQGMEGARDLALAMAQRGEGKLLDQFNNPDNPFAHYATTGPEIWRQTGGRITHFVSSMGTTGTITGVSRFLREQDKAVSIVGLQPEEGSSIPGIRRWPAEYMPGIFNAQLVDAVLDIHQLDAENTMRALAVKEGIFCGVSSGGAVAGALRIARDNPGAVVVAIVCDRGDRYLSTGVFGEENFAQGAGI
>NZ_CP046115.1|WP_154681440.1|3897763_3898171_+|DUF4440-domain-containing-protein
MHNPNLQLKAAIEACDRAISQEDYDTLLEYYAEDAALVVKPGMVVKGKENIRRAFIAIADYFQHRLVVTQGKMEIIEGGGNALVIMETRMDIPTAEAGTTQITRRATYVFRQQGERWLCTVDNSYGTDLLDAPEV
>NZ_CP046115.1|WP_154681439.1|3897367_3897742_+|hypothetical-protein
MQKILCAVIALFLALPAAAKLNAWQEARINAMLDALAQQKELTFVRNGDAHTCEEAVSHLRLKLGNTRNRINTAEQFIDKVASSSSITGKPYIVKIPGKNDENAKPYLHALLAETDKTLAAEEK
>NZ_CP046115.1|WP_154681438.1|3895907_3897206_+|transcriptional-regulator-PtsJ
MIVGKTASEIFDNIRYLVESGVLKAGDVLPPVRELAGKLSVNRNTVAAAYKRLVTSGLAISQGRNGTAIKTHNTLPALEGGDPSSTLKDISSGNPDPRRLANLKNYIQAVSLAPRLYGDAAVEPRLAVWASSWIGKDLARKAEINLASGAVDALERLLCALLLPGDSVAIEDPCFLSSINMLRYAGFKPSPVPVDGEGMQPAALEEALRNGARAVIITPRAHNPTGCSLSQSRARAIREILARYPQVLVIVDDHFALLSSTPWYSPIAAENQRWALVRSLSKTLGPDMRLAIVASDSETSAALRLRLNSGSQWVSHLLQDLVFACLNDDAFMASLDESRRHYRQQHEKLISGLARCGIAHLTPGDGLNFWFPLAEPSQRIALRLARAGWLVREGETFGINAPAHGLRLSIATLSDNEINKLANDLRQILQQQ
>NZ_CP046115.1|WP_154681437.1|3894958_3895825_-|pyridoxine/pyridoxal/pyridoxamine-kinase
MDQQDEIQSVLFNDKSRALQVDIVAVQSQVVYGSVGNSIAVPAIKQHGLRVMAVPTVLFSNTPHYDTFYGGVIPEEWFAGYLKALEERDALRELRAVTTGYMGSAVQIKRLAQWLLRIRQQHPGLCILVDPVIGDVDSGIYVKAEIPDAYRTHLLPLAQGITPNLFELETLSGLPCRNQQEAITAARSLLSDSLKWVVITSAPGADNATINVLVVSAESVEVVEHPRVETDLKGTGDLFCAELVSGLVCGLSLGEAAHAAAQRVLAVMTWTKRHGCDELILPPPGERV
>NZ_CP046115.1|WP_154681447.1|3903733_3904633_-|Dyp-type-peroxidase
MSQVQSGILPEHCHAAIWIEANVKGDVNALREASKVFADKLATFQAKYPEDKLGAVVAFGHDVWRQLSGGVGAEELKDFPVYGKGLAPSTQYDVLIHILSAKHELNFSVAQAAMAAFGAAVEVKEEIHGFRWIEERDLSGFVDGTENPAGEEIRREVAIINDGVDAGGSYVFVQRWEHNLKQLNRMSVTDQEMMIGRTKEANEEIDGDARPETSHLSRVDLTEDGKGLKIVRQSLPYGTASGTHGLYFCAYCARLHNIEQQLLSMFGDTDGKRDAMLRFTKPVTGGYYFAPSLDRLQAL
>NZ_CP046115.1|WP_154681448.1|3904726_3905302_-|RpoE-regulated-lipoprotein
MKSLRLLLCALPLVLTGCSTMSSVNWSAAYPWNWFGSSTEVTERGVGNLTASTPLNQQAISDALGSSYRLRSGMKTANGNIVRYFEALKDDQVALTINGESGTISRIDVRDSNIKAAGGVKIGTPFSDIYSKAFGNCQKGGHDSGAVVECKAEGSQHISYAFTGNWSGPEELMPSDDTLKNWKVSKIIWRR
>NZ_CP046115.1|WP_154681449.1|3905363_3905813_-|DUF2919-family-protein
MKNTELIPSDFDTHGRLRLPFLFWCVLLLQARTWVLFLMAGASRQQGDALLNLFYPDHDNFWLGLLPGIPAVLAFIISGHRQRFPRLWPAMRWLLVLSQFLLLVWQPLLWFSGESPSAVTISLLAADLYALWWLLSNHRLKACFREEQV
>NZ_CP046115.1|WP_004104360.1|3905799_3906225_-|GNAT-family-acetyltransferase
MEIRVFRQQDFEEVITLWERCDLLRPWNDPEMDIERKLNHDASLFLVAEVNGEVVGTVMGGYDGHRGSAYYLGVHPEYRGRGIANALLNRLEKKLIARGCPKINIMIREDNDVVQGMYERLGYEHSDVLCLGKRLIEDEEY
>NZ_CP046115.1|WP_154681450.1|3906436_3907312_+|N-acetylmuramoyl-L-alanine-amidase-AmiA
MSTFKPLKILASRRQVLKAGLAAITLSGIASQASAKEQQPLKTSNGHSKPAAKKKGAKRVVMLDPGHGGIDTGAIGHNGSKEKHVVLAIAKNVRSILRSNGIDARLTRSGDTFIPLYDRVEIAHQHGADLFMSIHADGFTNPSAAGASVFALSNRGASSAMAKYLSDRENRADEVAGKKTTDKDHLLQQVLFDLVQTDTIKNSLTLGSHILKKIKPVHKLHSSNTEQAAFVVLKSPSIPSVLVETSFITNPNEEKLLGTAAFRQKIATAIANGIISYFHWFDNQKAHSKRR
>NZ_CP046115.1|WP_154681451.1|3907311_3908211_+|oxygen-dependent-coproporphyrinogen-oxidase
MKPDAHQVKSFLLQLQDAICQKLSAVDGSAFVEDSWRREGGGGGRSRVLRDGGIFEQAGVNFSHVHGEAMPASATAHRPELAGRSFEAMGVSLVVHPRSPYIPTSHANVRFFIAEKPGADPVWWFGGGFDLTPYYGFEEDAVHWHRTAHDLCQPFGEEVYPRYKKWCDDYFFLKHRNEQRGIGGLFFDDLNTPDFDHCFDFMQAVGNGYTDAYLPIVERRKEMSWGERERDFQLYRRGRYVEFNLVWDRGTLFGLQTGGRTESILMSMPPLVRWEYAYQPEAGSPEAALSEFIQVRDWL
>NZ_CP046115.1|WP_154681452.1|3908234_3909287_-|HTH-type-transcriptional-regulator-EutR
MKKKQPANLHHLYHEALPEDVKLTPMIEVDNVHQRRTTDVYEHALTITAWQQIYDQLHPGKFHGEFTEILLDEIQVFREYTGLALRQSCLVWPNSFWFGIPATRGEQGFIGSQCIGSAEIATRPGGTEFELNTPDDYTILGVVISEDVISRQASFLHHPERVLHMLRNQSALEVKEQHKAALWRFVQQALATFSETPENLHQPAVRKVLGDNLLLAMGAMLEEAQPMVTAESISHQSYRRLLSRAREYVLENMSEPLTVLDLCNQLHVSRRTLQNAFHAILGIGPNAWLKRIRLNAVRRELISPWSQSVTVKDAAMQWGFWHLGQFATDYQQLFAEKPSLTLHQRMQQWA
>NZ_CP046115.1|WP_154681453.1|3909335_3909818_-|ethanolamine-utilization-microcompartment-protein-EutK
MINALGLLEVDGMVAAVDAADAMLKAANVRLLSHQVLDPGRLTLVVEGDLAACRAALDAGSAAAQRTGRVISRREIGRPEEDTQRLIGGFQRQPQAPEPPVKAESSAPLLALLASTRQGMTAGEVAAHFGWSLEEARKALEQLFSAGALRKRSSRYRLKN
>NZ_CP046115.1|WP_154681454.1|3909829_3910489_-|ethanolamine-utilization-microcompartment-protein-EutL
MPALDLIRPSVTAMRVIASVNDGFARELKLPPHIRSLGLITADSDDVTYIAADEATKQAMVEVVYGRSLYAGAAHGPSPTAGEVLIMLGGPNPAEVRAGLDAMMAHIEGGAAFQWANDAEDSAFLAHVVSRTGSYLSSTSGIALGDPIAYLVAPPLEATFGIDAAMKSADVQLVTYVPPPSETNYSAAFLTGSQAACKAACNAFTDAVLDIARHPIQRA
>NZ_CP046115.1|WP_154682769.1|3910498_3911386_-|ethanolamine-ammonia-lyase-subunit-EutC
MDQKQIEEIVRSVMASMGQPPTAAPAPQAAKCASQCEITAESCALDLGSPEAKGWIGVQQPHRAEVLAELKRSTAARVCTGRAGPRPRTLALLRFLADHSRSKDTVLKEVPEEWVKNQGLLEVRSEISDKNLYLTRPDMGRRLSPEAIEALKTQCVANPDVQVVVSDGLSTDAITVNYEEILPPLLSGLQQAGLKVGTPFFVRYGRVKIEDQIGEILGAKVVILLVGERPGLGQSESLSCYAVYSPRVATTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMTR

Crispr_ID: NZ_CP046115_4

• CRISPR_ID: NZ_CP046115_4
• CRISPR_location: 4281182-4281576
• CRISPR_type: Orphan
• Repeat_type: I-E
• Spacer_info: 6 spacers

Consensus repeat of NZ_CP046115_4

Consensus_repeat	Method
CGGTTTATCCCCGCTAGCGCGGGGAACAC	CRISPRCasFinder
CGGTTTATCCCCGCTAGCGCGGGGAACAC	CRT
CGGTTTATCCCCGCTAGCGCGGGGAACAC	PILER-CR

spacers of NZ_CP046115_4

>4.1|4281211|32|NZ_CP046115|CRISPRCasFinder,CRT
TGTAGAAGCAATTACTAAAATGCCAGAAATAT
>4.2|4281272|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR
ACAGACCTGCGCGATCCGGAGTTTCTGTATAA
>4.3|4281333|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR
GCATCACAGAAGACTGTAGCAATCGCGTATTA
>4.4|4281394|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR
GCGCGCCAGCGTGCCGGTCATAGCTGCGGCTT
>4.5|4281455|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR
CTCGTTCGGTGGCCTGTCCGTTAATCCCAGCT
>4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR
ATAAAAGGTTTAAAGACTCAGACTGCAAAATA

CRISPR arrays and Neighbor proteins around NZ_CP046115_4

CRISPR arrays

The CRISPR arrays of NZ_CP046115_4

>merge|NZ_CP046115|4|4281182-4281576|CRISPRCasFinder,CRT,PILER-CR
CGAATTATCCCCGCTGGCGCGGGGAACACTGTAGAAGCAATTACTAAAATGCCAGAAATATCGGTTTATCCCCGCTAGCGCGGGGAACACACAGACCTGCGCGATCCGGAGTTTCTGTATAACGGTTTATCCCCGCTAGCGCGGGGAACACGCATCACAGAAGACTGTAGCAATCGCGTATTACGGTTTATCCCCGCTAGCGCGGGGAACACGCGCGCCAGCGTGCCGGTCATAGCTGCGGCTTCGGTTTATCCCCGCTAGCGCGGGGAACACCTCGTTCGGTGGCCTGTCCGTTAATCCCAGCTCGGTTTATCCCCGCTAGCGCGGGGAACACATAAAAGGTTTAAAGACTCAGACTGCAAAATACGGTTTATCCCCGCTAGCGCGGGGAACAC

>NZ_CP046115|4|4|4281182-4281576|CRISPRCasFinder
CGAATTATCCCCGCTGGCGCGGGGAACAC	TGTAGAAGCAATTACTAAAATGCCAGAAATAT
CGGTTTATCCCCGCTAGCGCGGGGAACAC	ACAGACCTGCGCGATCCGGAGTTTCTGTATAA
CGGTTTATCCCCGCTAGCGCGGGGAACAC	GCATCACAGAAGACTGTAGCAATCGCGTATTA
CGGTTTATCCCCGCTAGCGCGGGGAACAC	GCGCGCCAGCGTGCCGGTCATAGCTGCGGCTT
CGGTTTATCCCCGCTAGCGCGGGGAACAC	CTCGTTCGGTGGCCTGTCCGTTAATCCCAGCT
CGGTTTATCCCCGCTAGCGCGGGGAACAC	ATAAAAGGTTTAAAGACTCAGACTGCAAAATA
CGGTTTATCCCCGCTAGCGCGGGGAACAC

>NZ_CP046115|4|2|4281182-4281576|CRT
CGAATTATCCCCGCTGGCGCGGGGAACAC	TGTAGAAGCAATTACTAAAATGCCAGAAATAT
CGGTTTATCCCCGCTAGCGCGGGGAACAC	ACAGACCTGCGCGATCCGGAGTTTCTGTATAA
CGGTTTATCCCCGCTAGCGCGGGGAACAC	GCATCACAGAAGACTGTAGCAATCGCGTATTA
CGGTTTATCCCCGCTAGCGCGGGGAACAC	GCGCGCCAGCGTGCCGGTCATAGCTGCGGCTT
CGGTTTATCCCCGCTAGCGCGGGGAACAC	CTCGTTCGGTGGCCTGTCCGTTAATCCCAGCT
CGGTTTATCCCCGCTAGCGCGGGGAACAC	ATAAAAGGTTTAAAGACTCAGACTGCAAAATA
CGGTTTATCCCCGCTAGCGCGGGGAACAC

>NZ_CP046115|4|3|4281243-4281576|PILER-CR
CGGTTTATCCCCGCTAGCGCGGGGAACAC	ACAGACCTGCGCGATCCGGAGTTTCTGTATAA
CGGTTTATCCCCGCTAGCGCGGGGAACAC	GCATCACAGAAGACTGTAGCAATCGCGTATTA
CGGTTTATCCCCGCTAGCGCGGGGAACAC	GCGCGCCAGCGTGCCGGTCATAGCTGCGGCTT
CGGTTTATCCCCGCTAGCGCGGGGAACAC	CTCGTTCGGTGGCCTGTCCGTTAATCCCAGCT
CGGTTTATCCCCGCTAGCGCGGGGAACAC	ATAAAAGGTTTAAAGACTCAGACTGCAAAATA
CGGTTTATCCCCGCTAGCGCGGGGAACAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046115.1|WP_154681754.1|4292492_4294130_-|CTP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl|CDD|235437
NZ_CP046115.1|WP_154681746.1|4277896_4279084_+|DUF3142-domain-containing-protein	unknown	unknown	gnl|CDD|371478
NZ_CP046115.1|WP_154681755.1|4294357_4295149_-|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl|CDD|236569
NZ_CP046115.1|WP_154681756.1|4295220_4297458_-|GTP-diphosphokinase	unknown	unknown	gnl|CDD|182797
NZ_CP046115.1|WP_154681747.1|4279070_4281122_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046115.1|WP_154681741.1|4271810_4272137_-|DUF3561-family-protein	unknown	unknown	gnl|CDD|371891
NZ_CP046115.1|WP_004104981.1|4274232_4275141_-|sulfate-adenylyltransferase-subunit-CysD	unknown	unknown	gnl|CDD|235375
NZ_CP046115.1|WP_154681749.1|4284472_4286185_-|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	unknown	unknown	gnl|CDD|237402
NZ_CP046115.1|WP_154681748.1|4283663_4284398_-|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl|CDD|234997
NZ_CP046115.1|WP_154681740.1|4270622_4271333_-|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl|CDD|234670
NZ_CP046115.1|WP_154681743.1|4272795_4274223_-|sulfate-adenylyltransferase-subunit-CysN	unknown	unknown	gnl|CDD|235349
NZ_CP046115.1|WP_154681745.1|4276803_4277862_+|aminopeptidase	unknown	unknown	gnl|CDD|182299
NZ_CP046115.1|WP_154681742.1|4272190_4272796_-|adenylyl-sulfate-kinase	unknown	unknown	gnl|CDD|179661
NZ_CP046115.1|WP_154681753.1|4291113_4292412_-|phosphopyruvate-hydratase	unknown	unknown	gnl|CDD|234617
NZ_CP046115.1|WP_154681751.1|4288463_4288826_+|6-carboxytetrahydropterin-synthase-QueD	unknown	unknown	gnl|CDD|238264
NZ_CP046115.1|WP_154681744.1|4275150_4276566_-|uroporphyrinogen-III-C-methyltransferase	unknown	unknown	gnl|CDD|182606
NZ_CP046115.1|WP_004104977.1|4271352_4271670_-|cell-division-protein-FtsB	unknown	unknown	gnl|CDD|179156
NZ_CP046115.1|WP_154681750.1|4286184_4287984_-|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	unknown	unknown	gnl|CDD|182862
NZ_CP046115.1|WP_154681752.1|4289937_4291047_+|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl|CDD|187547
NZ_CP046115.1|WP_154682784.1|4288881_4289553_-|7-carboxy-7-deazaguanine-synthase-QueE	unknown	unknown	gnl|CDD|275126

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046115.1|WP_154681754.1|4292492_4294130_-|CTP-synthase-(glutamine-hydrolyzing)	gnl|CDD|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NZ_CP046115.1|WP_154681746.1|4277896_4279084_+|DUF3142-domain-containing-protein	gnl|CDD|371478	pfam11340, DUF3142, Protein of unknown function (DUF3142). This bacterial family of proteins has no known function.	5.72205e-93
NZ_CP046115.1|WP_154681756.1|4295220_4297458_-|GTP-diphosphokinase	gnl|CDD|182797	PRK10872, relA, (p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional.	0
NZ_CP046115.1|WP_154681752.1|4289937_4291047_+|NAD-dependent-epimerase/dehydratase-family-protein	gnl|CDD|187547	cd05236, FAR-N_SDR_e, fatty acyl CoA reductases (FARs), extended (e) SDRs. SDRs are Rossmann-fold NAD(P)H-binding proteins, many of which may function as fatty acyl CoA reductases (FAR), acting on medium and long chain fatty acids, and have been reported to be involved in diverse processes such as biosynthesis of insect pheromones, plant cuticular wax production, and mammalian wax biosynthesis. In Arabidopsis thaliana, proteins with this particular architecture have also been identified as the MALE STERILITY 2 (MS2) gene product, which is implicated in male gametogenesis. Mutations in MS2 inhibit the synthesis of exine (sporopollenin), rendering plants unable to reduce pollen wall fatty acids to corresponding alcohols. This N-terminal domain shares the catalytic triad (but not the upstream Asn) and characteristic NADP-binding motif of the extended SDR family. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	2.99347e-64
NZ_CP046115.1|WP_154681741.1|4271810_4272137_-|DUF3561-family-protein	gnl|CDD|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	5.03264e-48
NZ_CP046115.1|WP_004104981.1|4274232_4275141_-|sulfate-adenylyltransferase-subunit-CysD	gnl|CDD|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
NZ_CP046115.1|WP_154681749.1|4284472_4286185_-|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	gnl|CDD|237402	PRK13504, PRK13504, NADPH-dependent assimilatory sulfite reductase hemoprotein subunit.	0
NZ_CP046115.1|WP_154681748.1|4283663_4284398_-|phosphoadenosine-phosphosulfate-reductase	gnl|CDD|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	5.41565e-138
NZ_CP046115.1|WP_154681740.1|4270622_4271333_-|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl|CDD|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	1.49877e-115
NZ_CP046115.1|WP_154681743.1|4272795_4274223_-|sulfate-adenylyltransferase-subunit-CysN	gnl|CDD|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
NZ_CP046115.1|WP_154681745.1|4276803_4277862_+|aminopeptidase	gnl|CDD|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
NZ_CP046115.1|WP_154681742.1|4272190_4272796_-|adenylyl-sulfate-kinase	gnl|CDD|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	7.48197e-147
NZ_CP046115.1|WP_154681753.1|4291113_4292412_-|phosphopyruvate-hydratase	gnl|CDD|234617	PRK00077, eno, enolase; Provisional.	0
NZ_CP046115.1|WP_154681751.1|4288463_4288826_+|6-carboxytetrahydropterin-synthase-QueD	gnl|CDD|238264	cd00470, PTPS, 6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a carrier-mediated active transport system. Most microbes and plants lack this system and must synthesize folates de novo from guanosine triphosphate. One enzyme from this pathway is PTPS which catalyzes the conversion of dihydroneopterin triphosphate to 6-pyruvoyl tetrahydropterin. The functional enzyme is a hexamer of identical subunits.	5.02613e-57
NZ_CP046115.1|WP_154681744.1|4275150_4276566_-|uroporphyrinogen-III-C-methyltransferase	gnl|CDD|182606	PRK10637, cysG, siroheme synthase CysG.	0
NZ_CP046115.1|WP_004104977.1|4271352_4271670_-|cell-division-protein-FtsB	gnl|CDD|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	2.04367e-62
NZ_CP046115.1|WP_154681750.1|4286184_4287984_-|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	gnl|CDD|182862	PRK10953, cysJ, NADPH-dependent assimilatory sulfite reductase flavoprotein subunit.	0
NZ_CP046115.1|WP_154681755.1|4294357_4295149_-|nucleoside-triphosphate-pyrophosphohydrolase	gnl|CDD|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	9.78663e-159
NZ_CP046115.1|WP_154682784.1|4288881_4289553_-|7-carboxy-7-deazaguanine-synthase-QueE	gnl|CDD|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	6.99007e-153

Protein sequences

>NZ_CP046115.1|WP_154681747.1|4279070_4281122_+|hypothetical-protein
MLARKLPLTTFLTAMLAAANGHACGPFFPNYLLENRHANLLYLPEGSFALESSRLVPIDPRLPQWRDTSTDKPTAPSAQEILITKIRASGSLEAAEKMAADLPAASRLYVLGAVAFTKRDSRARDYFRQVLALPAAQQGLWGLKARYSLARDLMHDYPEPRSESGYPLSDSAHSHGNQQGLREAFELYQQIIDAVRNGQEDPEQLSLASLGQQGRIKHWQSEPLAAAHLYARQAAQGSPTGSLSLRYTADILSDPENENFLQPGLDDPLIQQLLIASFFTRSSGPLYEPEPRPDDEQEIKNYHDALIAKLAQRINHDLPGSDRLIALAYRNGQYPLVTLLLKNATENGLTSWVQAKMALRAGDVKAATAWYAKAAASFPADEAWGSQPDNNEIIGDEFVIPTCRINAEQAILALNRNDYLEAMRLMYKAKEHYWPDLAQIAERVLTLKELTAFVDKYVPAPSPALLEQPENTERYSADVRLRTLLARRLMRAGQYQKALTYFALPENRDAAQAFINTLPKNGPKTAQAKAWWQAALLLRHQGMELTGYEMAPDFALYGGGYSWPYYDSGLEGKPAAKSWISAGERQRVQLSQPKQDNHFMHYRWQAVKLAEKAADLLPRKSQAYAAVLCNATDWIWAQDPTSVKRLYQRYVKNGAPFPWTENFGQNCPEPDFAVLRSNGKVRE
>NZ_CP046115.1|WP_154681746.1|4277896_4279084_+|DUF3142-domain-containing-protein
MMHLRFLLPLFLLLATCAGSIADNQVYIWQRVWKDDHKTALRQSHELFSTLRVLGLQIHPQEGSRIARVDTPLLQQDGRPVWLVVRLDGSLTQLDAAAILPQIQSIITHWRGAGVKLTAIEIDYDAPTSRLTDYQQLLALLRQALPPDLTLSITALPAWLSSAHLPDLLAAVDSSVLQLHSVLSPQQGLFDPAQARRWSRQYALISPHPFYLALPAYGSALISAPGQPERVESESLLGIFGERRELSVSPQQIDAFTRELEANPPKNFAGLVWFRLPLANDSRSWSLTTLEAVIRHRPLNTSWQWLALPDKANVSPESTLYELAIKNSGNIDAPLPIKITLQMENCLAADGAGGYRFAEERFYLTAPALLRAGRTRTIGWARCTSPPQGEFYVSP
>NZ_CP046115.1|WP_154681745.1|4276803_4277862_+|aminopeptidase
MFSALCRRLLPLALGAGFVFSAAPAMSALGDTANAQARHIATFFPGRMTGSPAEMLSADYLRQQFTQMGYKSDIRSFNTRYIYTDNEKRKNWQNVTGSTVIAAHEGKERQQIIIMAHLDTYAPQTNADVENNLGGLTLQGIDDNAVGLGVMLELAEQLKNVPTRYGIRFVATSGEEEGRLGAQNMLKRMSDAEKKNTLLVINLDNLVVGDKLYFNSGRSTPASVRKLTRDRALAIARSKGIIASSNPGLNPEYPKGTGCCNDASVFDEAGIPVLSVEATNWSLGRKDGYQQRAKSRSFPDGTSWHNIQLDNQQHIDKALPGRIAQRSRDVLKIMLPLVKELAKVEKKPAAKK
>NZ_CP046115.1|WP_154681744.1|4275150_4276566_-|uroporphyrinogen-III-C-methyltransferase
MEYLPIFAEVKERPVLVIGGGEIAARKIAFLLRAEAKVQIVADALIPELAGKVERQEIQWRATVFEERQLDDVFLAIAATEDDELNQRVYVAANARYRLVNVVDNQALCSFVFPSIVDRSPLLVAISSSGKAPVLSRILREKIEALLPTNLGRLAETASYWRHHIKTHLKTTAERRRFWERVFTGRFASLMLAGNKAEAEKALEDELRQPEKRPGEIILVGAGPGDAGLLTLRGLQAIQQADVVFYDNLVTPEVRELVRRDAETICVGKSASGVSVPQQEINRMLVEAAKEGKTVIRLKGGDPFIFGRGGEELQAAAEAAIPFQVVPGVTAAAGATAYAGIPLTHRDYAQSATFITGHFGAENSPLDWARLAQSGQTLAIYMGSLKAVEISAQLIANGRDGDTPVAVISRGTRADQQTKTGTLQQLGNLAKDVPMPALLVVGDVVRLHQQLAWFQHTTDAEGFGSSVINLA
>NZ_CP046115.1|WP_004104981.1|4274232_4275141_-|sulfate-adenylyltransferase-subunit-CysD
MDQKRLTHLRQLEAESIHIIREVAAEFSNPVMMYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTELDIWQYIYLENIEIVPLYLAAERPVLERDGMLMMIDDDRINLQPGEMIKKQMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
>NZ_CP046115.1|WP_154681743.1|4272795_4274223_-|sulfate-adenylyltransferase-subunit-CysN
MNTTIAQQIADEGGVEAYLHAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCDLAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAVNKMDLVDFSEETFNSIRESYLTFAEQLPGDLDIRFVPLSALEGDNVASQSDKMPWYSGPTLLEVLETVQIQRVVESQPLRFPVQYVNRPNLDFRGFSGTVASGRVTVGQRLKVLPSGVESTVARIVTFDGDLPEAAAGEAITIVLKDEIDISRGDLLVDAAVSLPAVQSASVDVVWMAEQALTPGQSYDIKIAGKKTRARVDGIQYQVDINNLTQREVESLPLNGIGLVDLTFDEPLVLDKYQDNPVTGGLIFIDRLTNVTVGAGMVREPNAQAQVGASQYSAFELELNQLIRKHFPHWDARDLLGGK
>NZ_CP046115.1|WP_154681742.1|4272190_4272796_-|adenylyl-sulfate-kinase
MARHDENIVWHAHSVTREDREALHGHKGAVVWFTGLSGSGKSTIAGALEEELHRLGVSTWLLDGDNVRHGLCSDLGFSDDDRKENIRRVGEVAKLMVDAGLVVLTAFISPHRAERQMVRERIGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYESPEKAEIHLDGEQLVTNLVHQLLDLLRQSDIIRS
>NZ_CP046115.1|WP_154681741.1|4271810_4272137_-|DUF3561-family-protein
MRNTQNISLIRSEPPPAAGDETTWSLSGAAVGFISWLLALGIPFLIYGSNTLFFLLYTWPFFLALMPVAVVVGIALHSLLDGKLQYSICATILTVGLMFGLLFFWLLG
>NZ_CP046115.1|WP_004104977.1|4271352_4271670_-|cell-division-protein-FtsB
MGKLTLLLLALLVWLQYSLWFGKNGLHDYSRVNDDVSAQQATNAKLKARNDQLFAEIDDLNGGQEAIEERARNELSMTRPGETFYRLVPDASKRNQAAGQQQNNR
>NZ_CP046115.1|WP_154681740.1|4270622_4271333_-|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MAATFPGVCAVLPAAGFGRRMQTECPKQYLSIGNKTILEHAVAALLANPLIKRVVIAVSPGDLRFSQLPLANHPQITVVDGGTERADSVLAGLKVIDEADWVLVHDAARPCLHQDDLSRLLQLRETSRTGGILAAPVRDTMKRAEPGRTAIAHTVERNDLWHALTPQFFPRELLVDCLTRALNEGAIITDEASALEYCGFHPELVAGRADNIKVTRPEDLALAEFYLTRSRHQEKA
>NZ_CP046115.1|WP_154681748.1|4283663_4284398_-|phosphoadenosine-phosphosulfate-reductase
MSVLDLNVLNELPKVDRVLQLAETNSQLEKLSAEARVAWALENLPGEYVLSSSFGIQAAVSLHLVNQVRPDIPVILTDTGYLFPETYQFIDELTDKLNLNLQVYRAKESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALQELNAQTWFAGLRREQSGSRAHLPVLAIQRGVFKVLPIIDWDNRTVYQYLQKHGLKYHPLWDQGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
>NZ_CP046115.1|WP_154681749.1|4284472_4286185_-|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit
MSEKHPGPLVVEGKLTDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAAQRLEPRHAMLLRCRLPGGVITTKQWQAIDKFAADNTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQKKVATTDEEPLLGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDNNWHLTLFIENGRILDYPGRPLKTGLLKIAKIHKGEFRITANQNLIIASVPEEQKAKIEKLARDHGLMNAVTPQRENSMACVSFPTCPLAMAEAERFLPSFIDKVEAVMSKHGVGDEHIVTRVTGCPNGCGRAMLAEVGLVGKAPGRYNLHLGGNRSGTRIPRMYRENITESEILDSIDELVGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDFWE
>NZ_CP046115.1|WP_154681750.1|4286184_4287984_-|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit
MTTQAPPSNLLPLNPEQMARLQAATTDFTPTQLAWVSGYFWGVLNQQPGSAIAAPAQAAEVPSITLISASQTGNARRIAEALRDDLQAAQLNVKLVNAGDYKFKQIASEKLLVVVTSTQGEGEPPEEAVALHKFLFSKKAPKLTDTAFAVFGLGDTSYEFFCQSGKDFDNKLAELGGERLLDRVDADVDYQTAAAEWRARVVEVLKARAPAAAPSQLVTSGAVNEIHTSPYTKEAPLTATLAVNQKITGRDSEKDVRHIEIDLGDSGLRYQPGDALGVWYQNDPALVKELVELLWLKGDEPVTVDGKTLPLAEALEWHFELTVNTGNIVENYATLTRSESLLPLVGDKAQLQHYAATTPIVDMVRFSPAQLDAQALIDLLRSLTPRLYSIASSQAEVESEVHVTVGVVRYDIEGRVRAGGASSFLADRVEEDGEVRVFIEHNDNFRLPANPQTPVIMIGPGTGIAPFRAFMQQRAAEGAEGKNWLFFGNPHFTEDFLYQVEWQSYVKEGVLSRIDLAWSRDQQQKVYVQDKLREQGAELWRWINDGAHIYVCGDANRMAKDVEQTLLEVIAEYGAMDAEAADEFLSELRVERRYQRDVY
>NZ_CP046115.1|WP_154681751.1|4288463_4288826_+|6-carboxytetrahydropterin-synthase-QueD
MSTTLFKDFTFEAAHHLPHVPEGHKCGRLHGHSFMVRLEITGEVDPHTGWIMDFAELKAAFKPTYDRLDHYYLNDIPGLENPTSEVLAKWIWEQMKPLVPLLSAVMIKETCTAGCVYRGE
>NZ_CP046115.1|WP_154682784.1|4288881_4289553_-|7-carboxy-7-deazaguanine-synthase-QueE
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWDKLADREVSLFSILAKTKESDKWGPASSEDLLAIIGRQGWTARHVVITGGEPCIHDLTPLTSLLEQNGFSCQIETSGTHEVRCTPHTWVTVSPKVNMRGGYDVLSQALQRADEIKHPVGRVRDIEALDELLETLTDEKPRIIALQPISQKDDATRLCIETCIARNWRLSMQTHKYLNIA
>NZ_CP046115.1|WP_154681752.1|4289937_4291047_+|NAD-dependent-epimerase/dehydratase-family-protein
MNTLLITGATGFLGGAVLESILNQMNATNLLLLVRADNSVAAVERVKENLRKFNISEERLTALTPGNILLGDLTNPQPFLDDPRLNQVTHVLNCAAVASFGNNPLIWKVNVEGTLQFARRMAQVSGLQRFLHVGTAMSCSPEPDSLVAESAMFRERAEHLVEYTHSKSTIERLMQQECPTLPLVIARPSIVVGHTHHGCQPSSSIFWVFSMGLMLQKFMCSMEDRIDVIPVDYCADALLMLLISPLARGEVVHISAGEENSVRFADIDRAMASALEQAPVGDKYAQVRYETLVKMRRELKDIFGPCNERLMLKAMRLYGAFATLNVRFSNDKLLSMGMPKPPRFTDYIDRCVQTTRGLSIPQQMAVDFK
>NZ_CP046115.1|WP_154681753.1|4291113_4292412_-|phosphopyruvate-hydratase
MSKIVKVIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVLKAVAAVNGPIAQAILGKDAKDQAGIDKIMIDLDGTENKSNFGANAILAVSLANAKAAAASKGQPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKSLKEAVRMGSEVFHNLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEDLTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIVNSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>NZ_CP046115.1|WP_154681754.1|4292492_4294130_-|CTP-synthase-(glutamine-hydrolyzing)
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTMMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMTRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLAGGEGHDVVLVEIGGTVGDIESLPFLEAIRQLAVDIGRENALFMHLTLVPYMAAAGEVKTKPTQHSVKELLSIGIQPDILVCRSDRAIPANERAKIALFCNVPEKAVISMKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLAEWEQVIYEEANPAGEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVTVNIKLIDSQDVETRGVEILKDLDAILIPGGFGYRGVEGKIATARYARENNIPYLGICLGMQVALIEFARNVAGMENANSTEFVPDCKYPVVALITEWRDEDGNVEVRSDKSDLGGTMRLGAQQCQLSDDSLVRQLYGEPTITERHRHRYEVNNMLLKPIENAGLRIAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAAGEYQKRQAK
>NZ_CP046115.1|WP_154681755.1|4294357_4295149_-|nucleoside-triphosphate-pyrophosphohydrolase
MTQIDRLLGIMQRLRDPENGCPWDKEQTFATIAPYTLEETYEVLDAISREDFADLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHIFGEASAGNSSEALARWEQIKSAERAEKSQHSALDDIPHSLPALMRAHKIQKRCSAVGFDWTSLGPVLGKVHEEIDEVMHEAQQAVVDEAKLEEEVGDLLFATVNLSRHLGVKAEVALQKANLKFERRFREVERIVAARGLEMTGVDLDTMEEVWQEVKRQETDL
>NZ_CP046115.1|WP_154681756.1|4295220_4297458_-|GTP-diphosphokinase
MVAVRSAHLNKAGEFDPKKWIASLGISSQQSCERLAETWDYCREKTQGHPQAELLLWRGVEMVEILSMLSMDIDTLRAAMLFPLADGNVVSEEIMQESVGKSVVTLIHGVRDMAAIRQLKATHTDSVSSEQVDNIRRMLLAMVDDFRCVVIKIAERIAHLREVKDAPEDERVLAAKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPAEYKRIAKLLHERRIDREHYIDEFVGHLRSEMKTEGVKAEVYGRPKHIYSIWRKMQKKHLAFDELFDVRAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTIEIQIRTRQMHEDAELGVAAHWKYKEGASAGVSGGRGYEDRIAWLRKLIAWQEEMADSGEMLDEVRSQVFDDRVYVFTPKGDVVDLPSGSTPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGDQIEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAGRQILDDELEHLGISLKDAEKYLLPRYNFNEQDELLAAIGGGDIRLNQMVNFLQAQFNKPSAAEQDAAALKQLQQKTYTPQNRNKDNGRVVVEGVGNLMHHIARCCQPIPGDEIVGFITQGRGISVHRADCDQLAELQSHAPERIVDAVWGESYSAGYSLVVRVQANDRSGLLRDITTILANEKVNVLGVASRSDTKHQLATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARRLHGG

Crispr_ID: NZ_CP046115_5

• CRISPR_ID: NZ_CP046115_5
• CRISPR_location: 4403564-4403691
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP046115_5

Consensus_repeat	Method
TCCCGGATTGCGGCTGACGCCTTATCCGGGCTACA	CRISPRCasFinder

spacers of NZ_CP046115_5

>5.1|4403599|58|NZ_CP046115|CRISPRCasFinder
ACATCGCCGCATGCACGGAACGGCAGCCTGGCTAAGCGCTGCGCATGCGGGGGGATAT

CRISPR arrays and Neighbor proteins around NZ_CP046115_5

CRISPR arrays

The CRISPR arrays of NZ_CP046115_5

>merge|NZ_CP046115|5|4403564-4403691|CRISPRCasFinder
TCCCGGATTGCGGCTGACGCCTTATCCGGGCTACAACATCGCCGCATGCACGGAACGGCAGCCTGGCTAAGCGCTGCGCATGCGGGGGGATATTCCCGGATTGCGGCTGACGCCTTATCCGGGCTACA

>NZ_CP046115|5|5|4403564-4403691|CRISPRCasFinder
TCCCGGATTGCGGCTGACGCCTTATCCGGGCTACA	ACATCGCCGCATGCACGGAACGGCAGCCTGGCTAAGCGCTGCGCATGCGGGGGGATAT
TCCCGGATTGCGGCTGACGCCTTATCCGGGCTACA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046115.1|WP_154681837.1|4400248_4400944_+|DNA-mismatch-repair-endonuclease-MutH	unknown	unknown	gnl|CDD|179923
NZ_CP046115.1|WP_154681847.1|4413077_4414088_+|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl|CDD|380494
NZ_CP046115.1|WP_004124584.1|4394798_4395593_-|thymidylate-synthase	unknown	unknown	gnl|CDD|234984
NZ_CP046115.1|WP_154681844.1|4409168_4409942_-|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|182318
NZ_CP046115.1|WP_004124593.1|4399035_4399566_-|RNA-pyrophosphohydrolase	unknown	unknown	gnl|CDD|234820
NZ_CP046115.1|WP_154681839.1|4402402_4403443_+|NADP(H)-dependent-aldo-keto-reductase	unknown	unknown	gnl|CDD|236727
NZ_CP046115.1|WP_154681833.1|4393574_4394138_-|prepilin-peptidase-dependent-protein	unknown	unknown	gnl|CDD|236714
NZ_CP046115.1|WP_154681840.1|4403747_4404941_-|lysophospholipid-transporter-LplT	unknown	unknown	gnl|CDD|236879
NZ_CP046115.1|WP_154681848.1|4414218_4415481_-|diaminopimelate-decarboxylase	unknown	unknown	gnl|CDD|236867
NZ_CP046115.1|WP_154681836.1|4396776_4399023_-|phosphoenolpyruvate--protein-phosphotransferase	unknown	unknown	gnl|CDD|182937
NZ_CP046115.1|WP_154681835.1|4395599_4396475_-|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl|CDD|234599
NZ_CP046115.1|WP_154681834.1|4394128_4394593_-|prepilin-peptidase-dependent-protein	unknown	unknown	gnl|CDD|236704
NZ_CP046115.1|WP_154681841.1|4404933_4407093_-|bifunctional-acyl-ACP--phospholipid-O-acyltransferase/long-chain-fatty-acid--ACP-ligase	unknown	unknown	gnl|CDD|181207
NZ_CP046115.1|WP_154681843.1|4408692_4409172_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|173926
NZ_CP046115.1|WP_154681842.1|4407715_4408732_+|HTH-type-transcriptional-regulator-GalR	unknown	unknown	gnl|CDD|182681
NZ_CP046115.1|WP_154681845.1|4411444_4412782_-|PTS-sugar-transporter-subunit-IIC	unknown	unknown	gnl|CDD|224372
NZ_CP046115.1|WP_154682785.1|4410009_4411437_-|family-1-glycosylhydrolase	unknown	unknown	gnl|CDD|225343
NZ_CP046115.1|WP_154681846.1|4412806_4413010_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046115.1|WP_154681838.1|4401109_4401823_+|TerC-family-protein	unknown	unknown	gnl|CDD|223930
NZ_CP046115.1|WP_004105255.1|4401946_4402165_+|YgdI/YgdR-family-lipoprotein	unknown	unknown	gnl|CDD|380215

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046115.1|WP_154681837.1|4400248_4400944_+|DNA-mismatch-repair-endonuclease-MutH	gnl|CDD|179923	PRK05070, PRK05070, DNA mismatch repair protein; Provisional.	1.01899e-165
NZ_CP046115.1|WP_154681847.1|4413077_4414088_+|LacI-family-DNA-binding-transcriptional-regulator	gnl|CDD|380494	cd06270, PBP1_GalS-like, ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism. Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism. Transcription of the galactose regulon genes is regulated by Gal iso-repressor (GalS) and Gal repressor (GalR) in different ways, but both repressors recognize the same DNA binding site in the absence of D-galactose. GalS is a dimeric protein like GalR,and its major role is in regulating expression of the high-affinity galactose transporter encoded by the mgl operon, whereas GalR is the exclusive regulator of galactose permease, the low-affinity galactose transporter. GalS and GalR are members of the LacI-GalR family of transcription regulators and both contain the type 1 periplasmic binding protein-like fold. Hence, they are homologous to the periplasmic sugar binding of ABC-type transport systems.	2.04457e-126
NZ_CP046115.1|WP_004124584.1|4394798_4395593_-|thymidylate-synthase	gnl|CDD|234984	PRK01827, thyA, thymidylate synthase; Reviewed.	0
NZ_CP046115.1|WP_154681844.1|4409168_4409942_-|GntR-family-transcriptional-regulator	gnl|CDD|182318	PRK10225, PRK10225, Uxu operon transcriptional regulator.	6.03635e-76
NZ_CP046115.1|WP_004124593.1|4399035_4399566_-|RNA-pyrophosphohydrolase	gnl|CDD|234820	PRK00714, PRK00714, RNA pyrophosphohydrolase; Reviewed.	3.76878e-106
NZ_CP046115.1|WP_154681839.1|4402402_4403443_+|NADP(H)-dependent-aldo-keto-reductase	gnl|CDD|236727	PRK10625, tas, putative aldo-keto reductase; Provisional.	0
NZ_CP046115.1|WP_154681833.1|4393574_4394138_-|prepilin-peptidase-dependent-protein	gnl|CDD|236714	PRK10557, PRK10557, prepilin peptidase-dependent protein.	7.02985e-94
NZ_CP046115.1|WP_154681840.1|4403747_4404941_-|lysophospholipid-transporter-LplT	gnl|CDD|236879	PRK11195, PRK11195, lysophospholipid transporter LplT; Provisional.	0
NZ_CP046115.1|WP_154681848.1|4414218_4415481_-|diaminopimelate-decarboxylase	gnl|CDD|236867	PRK11165, PRK11165, diaminopimelate decarboxylase; Provisional.	0
NZ_CP046115.1|WP_154681836.1|4396776_4399023_-|phosphoenolpyruvate--protein-phosphotransferase	gnl|CDD|182937	PRK11061, PRK11061, phosphoenolpyruvate--protein phosphotransferase.	0
NZ_CP046115.1|WP_154681835.1|4395599_4396475_-|prolipoprotein-diacylglyceryl-transferase	gnl|CDD|234599	PRK00052, PRK00052, prolipoprotein diacylglyceryl transferase; Reviewed.	5.15297e-115
NZ_CP046115.1|WP_154681834.1|4394128_4394593_-|prepilin-peptidase-dependent-protein	gnl|CDD|236704	PRK10506, PRK10506, prepilin peptidase-dependent protein.	7.06906e-71
NZ_CP046115.1|WP_154681841.1|4404933_4407093_-|bifunctional-acyl-ACP--phospholipid-O-acyltransferase/long-chain-fatty-acid--ACP-ligase	gnl|CDD|181207	PRK08043, PRK08043, bifunctional acyl-ACP--phospholipid O-acyltransferase/long-chain-fatty-acid--ACP ligase.	0
NZ_CP046115.1|WP_154681843.1|4408692_4409172_-|GNAT-family-N-acetyltransferase	gnl|CDD|173926	cd04301, NAT_SF, N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate. NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.	5.59771e-11
NZ_CP046115.1|WP_154681842.1|4407715_4408732_+|HTH-type-transcriptional-regulator-GalR	gnl|CDD|182681	PRK10727, PRK10727, HTH-type transcriptional regulator GalR.	0
NZ_CP046115.1|WP_154681845.1|4411444_4412782_-|PTS-sugar-transporter-subunit-IIC	gnl|CDD|224372	COG1455, CelB, Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism].	5.94373e-127
NZ_CP046115.1|WP_154682785.1|4410009_4411437_-|family-1-glycosylhydrolase	gnl|CDD|225343	COG2723, BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase [Carbohydrate transport and metabolism].	2.25367e-144
NZ_CP046115.1|WP_154681838.1|4401109_4401823_+|TerC-family-protein	gnl|CDD|223930	COG0861, TerC, Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism].	2.9306e-76
NZ_CP046115.1|WP_004105255.1|4401946_4402165_+|YgdI/YgdR-family-lipoprotein	gnl|CDD|380215	NF033216, lipo_YgdI_YgdR, YgdI/YgdR family lipoprotein. Members of this family are exclusively lipoproteins of small size, including YgdI and YgdR from E. coli K-12.	1.53505e-34

Protein sequences

>NZ_CP046115.1|WP_154681839.1|4402402_4403443_+|NADP(H)-dependent-aldo-keto-reductase
MQYHRIPHSSLEISTLGLGTMTFGEQNSEADAHEQLDYAVSQGINLIDVAEMYPVPPRPETQGLTETYVGNWLAKRGNREKLVIASKVSGPARNNDSSIRPDHKLDRKNIREALHDSLKRLQTDYLDLYQVHWPQRPTNCFGKLGYTWADSAPVVTLLDTLEALAEFQRAGKIRYIGVSNETAFGVMRYLHLADKHDLPRIVTIQNPYSLVNRSYEVGLAEVSQYEGVELLAYSCLAFGTLTGKYLNGAKPAGARNTLFSRFTRYSGEQTQKAVAAYVDIAKRHNLDPAQMALAFVRRQPFVASTLLGATTMEQLKTNVESLHMELSAEVLAEIEAVHQVYTYPAP
>NZ_CP046115.1|WP_004105255.1|4401946_4402165_+|YgdI/YgdR-family-lipoprotein
MKKWAVLISAVGLAFSVSGCSSDYVMATKDGRMILTDGKPAIDDDTGLISYEDQQGNKMQINRDDVSQIIKR
>NZ_CP046115.1|WP_154681838.1|4401109_4401823_+|TerC-family-protein
MLFAWVTDPNAWLALGTLTLLEIVLGIDNIIFLSLVVAKLPTAQRAHARRIGLMGAMLMRLALLASIAWVVKLTNPLFTVLGQEISFRDLILLLGGLFLIWKASKEIHESIEGEEEGLKTNVHSFMGAIVQIMLLDIIFSLDSVITAVGLSDHLFIMMAAVVIAVLVMMVAARSIGDFVDRHPSVKMLALSFLILVGFTLMLESFDVHVPKGYIYFAMFFSIAVESLNLLRNKKNPL
>NZ_CP046115.1|WP_154681837.1|4400248_4400944_+|DNA-mismatch-repair-endonuclease-MutH
MPTIAPLLFPPQSQEQLLAQAQQLAGYSLGELAQLAGIPIPRDLKRDKGWIGILLEIWLGASAGSKPEQDFAALGVELKTIPIDSLGRPLETTFVCVAPLTGNSGVTWESSHVRHKLKRVLWVPVEGERSIPLADRRVGSPLLWSPSEEEDRQLRMDWEELMDLIVLGQVERITARHGEVLQLRPKAANSKALTEAVGAHGEPILTLPRGFYLKKNFTAALLARHFLLSAK
>NZ_CP046115.1|WP_004124593.1|4399035_4399566_-|RNA-pyrophosphohydrolase
MIDDDGYRPNVGIVICNRQGQVMWARRYGQHSWQFPQGGINPGESAEQAMYRELFEEVGLSRKDVRILASTRNWLRYKLPKRLVRWDTKPVCIGQKQKWFLLQLIGSDADVNMQTSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFASVTMALAESTPKPQSAPAYRRKRG
>NZ_CP046115.1|WP_154681836.1|4396776_4399023_-|phosphoenolpyruvate--protein-phosphotransferase
MLTRLREIVEKVASAPRLNEALDILVTDVCAAMETEVCSVYLADNDRRCYYLMATRGLKKPRGRIVALAFDEGLVGLVGRLAEPINLADAQKHPSFKYIPAVKEGRFRAFLGVPIIQRRQLLGVLVVQQRELRQFDESEESFLVTLATQIAGILSQSQLNALFGQYRQTRIRALPASSGVAIAEGWMDVSLPLMEQVYEASTLDTASERERLTGALEEAANEFRRYSKRYSAGAQKETAAIFDLYSHLLSDARLRRELFAEVDKGAVAEWAVKKIIEKFAEQFAALSDGYLKERAGDLRTLGQRLLFHLDDSIQGPNTWPERIVLVADELSATTLAEVPQDRLAGVVVRDGAANSHAAIMVRALGIPTVMGADIQPSLLHGHTLIVDGYRGELLVDPEPVLLHEYQRLISEENELSRLAEDDLQRASELKSGERVKVMLNAGLSPEHEEKLGNFVDGIGLYRTEIPFMLQSGFPSEEEQVAQYQGMLQMFNDKSVTLRTLDIGADKQLPYMPISEENPCLGWRGIRITLDQPEIFLVQVRAMLRANAATGNLSILLPMVTSLDEVDEARRLIDRASREVEEMIGYAIPRPRLGVMLEVPSMVFMLPQLANRVDFISVGTNDLTQYILAVDRNNTRVASMYDSLHPGVLRALAMIASDAERFGIDLRLCGEMAGDPMCVTILIGMGYRHLSMNGRSVARVKYLLRRIDINEAQELSQRSLEAQMTAEVRHQVAAFMERRGLGGLIRGGR
>NZ_CP046115.1|WP_154681835.1|4395599_4396475_-|prolipoprotein-diacylglyceryl-transferase
MNSGYLHFPEFDPVIFSIGPVSLHWYGLMYLVGFVFAMWLATRRANRPGSGWTKNEVENLLYAGFLGVFLGGRLGYVFFYNLPVFLDDPLYLFRVWDGGMSFHGGLIGVILVMIIFAKRTKRTFFQVADFIAPLIPFGLGAGRLGNFINGELWGRVDPSFHYTMIFPGSRAEDLALLPSHPEWQSLFDTYGALPRHASQLYEMALEGVVLFLILNLFIRKPRPTGSVSGLFLIGYGLFRIIVEFFRQPDAQFTGGWVQYISMGQILSIPMVVAGIIMMVWAYRCRPQQQNS
>NZ_CP046115.1|WP_004124584.1|4394798_4395593_-|thymidylate-synthase
MKQYLDLMQKVLDEGTQKNDRTGTGTVSIFGHQMRFNLQEGFPLVTTKRCHLRSIIHELLWFLQGDTNVAYLHENNVTIWDEWADENGDLGPVYGKQWRSWPAPDGRHIDQISTVMEQLKNDPDSRRIIVSAWNVGELNKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLVHMVAQQCDLEVGDFVWTGGDTHLYSNHMEQTHLQLSREPRALPKLVIKRKPASIFDYRFEDFEIEGYDPHPGIKAPVAI
>NZ_CP046115.1|WP_154681834.1|4394128_4394593_-|prepilin-peptidase-dependent-protein
MDREHGYTLIETLVTMTLVVILGSSGLYGWRSWQQQQRLWQTACQVRDYLVLLRDDANWHNRDRVLNSGQSAAGWCLSASGTTDCSVRSAFTLQPLWPEVSLSAMTPGLGFYGLRNTAWAGHIRLQSAAGKWNIIVSNWGRIRLCRGEETASCL
>NZ_CP046115.1|WP_154681833.1|4393574_4394138_-|prepilin-peptidase-dependent-protein
MSLKYRGFSLPETLIAMAISAVLLLGSARFLPALQWAALRQTRQLSLENELWQRVYTVAKHLQRAGYCRGRCSGQALYIAGGGDCLLVRWDGNSDGIWNSSPSSEADTTGFRLRDGALETLRGAEECSGKGWEKMTNPAAMKVTVFQVTRQNKANFSPELSITLAAHSVADPQIRARAEYSVTGYNL
>NZ_CP046115.1|WP_154681840.1|4403747_4404941_-|lysophospholipid-transporter-LplT
MSESAHTNNSLYSKGMMAVICAQFLSAFGDNALLFATLALMKQLFYPEWSQPILQMLFVGAYILFAPFVGQFADSFAKGRVMMVANGLKLIGAGCICFGVNPFIGYTLVGIGAAAYSPAKYGILGELTTGDKLVKANGLMESSTIAAILLGSMAGGILADWHVVAALGVCAVVYAGAVVANLWIPKLPAARPGQSWRFRPMTHRFFSACKTLWRNGETRFSLVGTSLFWGAGVTLRFLLVLWVPVALGITSNAMPTYLNAMVAVGIVLGAGAAAKLVTLETVSRCMPAGILIGVAVIFFAVQQALLPAFALLLLLGAFGGFFIVPLNALLQERGKHTVGAGNAIAVQNLGENVAMLLMLGLYSLAVSIGIPVVGVGIGFGVVFALAITALWIWGRRK
>NZ_CP046115.1|WP_154681841.1|4404933_4407093_-|bifunctional-acyl-ACP--phospholipid-O-acyltransferase/long-chain-fatty-acid--ACP-ligase
MLLGFFRLLFKGLYRVKLTGDTQALYQQKVLITPNHVSFLDGILLALFLPVRPVFAVYSSISERWFMRALKPIIDFVPLDPTKPMSIKQLVRLIEQGRPVVIFPEGRISVSGSLMKIYDGAAFVAAKSQATIVPMRIEGAELTPFSRLKGLVKRRLFPRIQLHLLPPTHLPMPDAPRARDRRKLAGEMLHQIMMEARMAVRPRETLYESLLAAQDRFGARKNCVEDINFQPDTYRKLLTKTLFVARILEKYSVQGEKIGLMLPNAGISAAVIFGAIARGRIPAMMNYTAGVKGLSSAITAAEIKTIFTSRTFLDKGKLWHLPEQLTQVRWVFLEDLKGDVTAADKLWIFAHLLMPKLAQVKQQPEDAAMILFTSGSEGNPKGVVHSHKSLLANVEQIKTIADFTANDRFMSALPLFHSFGLTVGLLTPLFTGAEVFLYPSPLHYRVVPELVYDRNCTVLFGTSTFLGNYARFANPYDFYRLRYVVAGAEKLQESTKQIWQDKFGLRILEGYGVTECAPVVSINVPMAAKVGTVGRILPGMDARLLAMPGIEEGGRLQLKGPNIMNGYLRVENPGVLEAPAAENQHGEVENGWYDTGDIVSFDEQGYVRIQGRAKRFAKIAGEMVSLEMVEQVALAVSPDKMHATAIKQDASKGEALVLFTTDNELNREKLLRYAREHGVPELAVPRDIRWLKQLPVLGSGKPDFVTLKDMVEQTEHSDE
>NZ_CP046115.1|WP_154681842.1|4407715_4408732_+|HTH-type-transcriptional-regulator-GalR
MATIKDVARLAGVSVATVSRVINNSPKASEASRQSVGAAMETLNYHPNANARALAQQSTETVGLVVGDVSDPFFGAMVKAVEQVAYNTGNFLLIGNGYHSLHKERQAIEQLIRHRCAALVVHAKIIPDDELAALMKQIPGMVLINRILPGFEQRCVALDDRYGAWLATRHLIQQGHTRIGYLCSNHAISDAEDRLQGYYAALKESDLPCNDRLVTFAEPDESGGEQAMTELLGRGRNFTAVACYNDSMAAGAMGVLNDNGIDVPREISLIGFDDVLISRYVRPRLTTVRYPIITMATQAAELALALAEHRPLPEITHLFSPTLVRRHSVVSPLDNDKS
>NZ_CP046115.1|WP_154681843.1|4408692_4409172_-|GNAT-family-N-acetyltransferase
MIIQPLYAEPRHATRVAEWLWQAFGGETLPQAFFASIVEHSQTPEALPITFIAVEGERLLGTVGLWRCDLISRQDLYPWLAALYVAPEARGRGLAGKLQQHVIGYARTQGYSELFLYSACRDFYERFGWQYIGEGLDYPATAVSLYRYDLSLSRGETTE
>NZ_CP046115.1|WP_154681844.1|4409168_4409942_-|GntR-family-transcriptional-regulator
MEKAIIPPEKKPYQEIGDDLRAQIAQGHYPVGSRLPPERHIAETYGVSRTIVREALLMLELQGTVDIRQGSGVYVMRIPHEDDSEEEQMLSSDVGPFEILQARQLLESNIAAFAAKMATRADIDNLKRIIEQEQRAIAANDTSQDNARLFHLVLAGATQNQMLLATVERIWLQMDSSPLWQQFNVHIASRAYRLKWLGDRQTLLAALRRRDVMGAWQAMWQHLENVKNSLLELSDEDAPDFDGYLFESVPIFQGKLV
>NZ_CP046115.1|WP_154682785.1|4410009_4411437_-|family-1-glycosylhydrolase
MTTVKMTIPHDFILGAAASAWQTEGWSGKKEGQDSWPDLWYKNDRHVWHNGYGPAVATDFINRFREDVQLMKLAGLTHYRTSINWSRFLTDYENVTVDEAYAAYYDQLFDELLANGIEPMICLEHYELPGYLLEHYGGWASKKVVELFVQYAEKVFARYHHKVTRWFTFNEPIVVQTRVYLDALRWPYEQSTGTWMQWNHHKVLATAKVVQLFREQGYRGTVGCILNPEVTYPRSKAPHDVRAAELYDLFYNRIFLDPLVHGAYPPELVALLEQHDVSWDYCAEELTIIRENMVDELGINLYYPHRVKAPSRAWHPQTPFHPAYYYEPFELPGRRMNSSRGWEIYPQIVFDMAMRIKRDYRNIPWFVAESGMGVENEGQFRNGEGTIVDDYRIRFISEHLWHTLRAREAGANCHGYMLWAFTDNVSPMNAFKNRYGLIEIDLQNNRARRPKASASWFRQLRESRELTLDIDDEWR
>NZ_CP046115.1|WP_154681845.1|4411444_4412782_-|PTS-sugar-transporter-subunit-IIC
MALQDKLIDSLGSFATKFNSYRYIMAIKSAFITLMPVIIVGAFSVLISNMVLDPKNGLASFQALSFLAALKPITSAINYATLNFLNIGAVFLIGIELGRINGIKSLFPGLLAVICFICVTPTTVEMMVDGQMHEVKDVLLRQFSDTRSLFLGMFIAILSVEVYCWLEGRKGLKIKMPDTVPPNVSASFSALIPAIITTTVIATFGFIFHQATGMYLYDAVYQVVQQPLERVVQSLPGILLLMFVAQLFWVIGIHGNQMIKPIREPLLLGAITVNMSAFEQGKEVPNIITMPFWDVYMSIGGSGLTIGLLIAVMIATKRKEMKEIAKLSIGPGLFNINEPVIFGMPIMLNPILAIPFIITPLVTGSIGYFATAAGFAGKAVVMVPWTTPPLINAWLSTAGSMGAVVTQLICIVTAVLIYLPFVKIASRRAENAQRQAENAQASQNA
>NZ_CP046115.1|WP_154681846.1|4412806_4413010_-|hypothetical-protein
MAAQKNYRDHAFAGMGHAKNKTVNAVCQFSLFWNANERVESSVTELFRSGDYFLVCQWVFGCTPGAL
>NZ_CP046115.1|WP_154681847.1|4413077_4414088_+|LacI-family-DNA-binding-transcriptional-regulator
MATMLDVSIRAGVSKATVSRVLNGTGQVKESTRQQVFKAMEELGYRPNFLARSLANRTSNSIGLVVSTFDGFYFGRLLQQASRQTEAWGKQLIVTDGHDAPEREEEAVQMLADRQCDAIVLYTRHMSEKKIMSLIESIDMPLVVINRDVSQARERCVFFEQQDAAFQAVEYLITQGHRDIACITVPMHTPTGKARLEGYRNALKKHGIKWDPAKVKYGDSTMSRGYELCRELLEEKIPFSALFSCNDDMALGASKALYQAGLRIPQDVSLFGFDDAPSAKWLEPGLSTVYLPIDNMITTAIDQAIKLANSQPIETIPPFTGTLVLRESVTTGPYYK
>NZ_CP046115.1|WP_154681848.1|4414218_4415481_-|diaminopimelate-decarboxylase
MPHSLYATDTDLTADNLLRLPAEFGCPVWVYDAQIIRRQIAQLNKFDVIRFAQKACSNIHILRLMREQGVKVDSVSLGEIERALAAGYDPHQHPEDIVFTADLIDDATLARVKELQIPVNAGSIDMLSQLGEVSPGHRVWLRVNPGFGHGHSQKTNTGGENSKHGIWHSHLPAALEVMRRYQLQLVGIHMHIGSGVDYGHLEQVCGAMVRQVIEFGQDLQAISAGGGLSIPYHDDEEAIDTDHYFGLWNAAREQVAKHLGHPVALEIEPGRFLVAESGVLVSQVRSVKEMGSRHFVLIDAGFNDLMRPAMYGSYHHITALAADGRDLSAAAEIETVVAGPLCESGDVFTQQEGGKVETRLLPAVAPGDYLVLHDTGAYGASMSSNYNSRPLLPEVLFDNGKARLIRRRQTIEELLALELL

Crispr_ID: NZ_CP046115_6

• CRISPR_ID: NZ_CP046115_6
• CRISPR_location: 4433421-4433527
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP046115_6

Consensus_repeat	Method
TTTTTATGCCCGGCGTCTTCCCCGGAT	CRISPRCasFinder

spacers of NZ_CP046115_6

>6.1|4433448|53|NZ_CP046115|CRISPRCasFinder
TGCGCTGCGCTTATCCGGGCTACATGACTGACCCTGCCCTCCTTTTGGAGGGC

CRISPR arrays and Neighbor proteins around NZ_CP046115_6

CRISPR arrays

The CRISPR arrays of NZ_CP046115_6

>merge|NZ_CP046115|6|4433421-4433527|CRISPRCasFinder
TTTTTATGCCCGGCGTCTTCCCCGGATTGCGCTGCGCTTATCCGGGCTACATGACTGACCCTGCCCTCCTTTTGGAGGGCTTTTTATGCCCGGCGTTTTCCCCGGAT

>NZ_CP046115|6|6|4433421-4433527|CRISPRCasFinder
TTTTTATGCCCGGCGTCTTCCCCGGAT	TGCGCTGCGCTTATCCGGGCTACATGACTGACCCTGCCCTCCTTTTGGAGGGC
TTTTTATGCCCGGCGTTTTCCCCGGAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046115.1|WP_154681854.1|4422469_4423597_+|oligogalacturonate-lyase	unknown	unknown	gnl|CDD|291262
NZ_CP046115.1|WP_154681871.1|4442367_4443015_-|type-1-fimbrial-protein	unknown	unknown	gnl|CDD|185109
NZ_CP046115.1|WP_154681855.1|4423708_4425052_-|porin	unknown	unknown	gnl|CDD|374908
NZ_CP046115.1|WP_154681868.1|4440161_4440863_+|PilZ-domain-containing-protein	unknown	unknown	gnl|CDD|227868
NZ_CP046115.1|WP_154681866.1|4437555_4438785_+|transporter	unknown	unknown	gnl|CDD|273283
NZ_CP046115.1|WP_154681863.1|4434635_4435811_-|acetyl-CoA-C-acyltransferase	unknown	unknown	gnl|CDD|180261
NZ_CP046115.1|WP_154681860.1|4430880_4431642_-|2-dehydro-3-deoxy-D-gluconate-5-dehydrogenase-KduD	unknown	unknown	gnl|CDD|181605
NZ_CP046115.1|WP_154681853.1|4421116_4422403_+|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|224567
NZ_CP046115.1|WP_154681857.1|4426672_4427914_-|oligosaccharide-MFS-transporter	unknown	unknown	gnl|CDD|236549
NZ_CP046115.1|WP_154681861.1|4432184_4433360_+|oligogalacturonate-lyase	unknown	unknown	gnl|CDD|291262
NZ_CP046115.1|WP_154681864.1|4435988_4436861_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223656
NZ_CP046115.1|WP_154681859.1|4429151_4430570_-|sugar-porter-family-MFS-transporter	unknown	unknown	gnl|CDD|273317
NZ_CP046115.1|WP_154681867.1|4438901_4439774_+|oxidoreductase	unknown	unknown	gnl|CDD|236676
NZ_CP046115.1|WP_154681869.1|4440867_4441452_+|LuxR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197715
NZ_CP046115.1|WP_154681870.1|4441593_4442310_+|EAL-domain-containing-protein	unknown	unknown	gnl|CDD|183222
NZ_CP046115.1|WP_154681856.1|4425220_4426660_-|sucrose-6-phosphate-hydrolase	unknown	unknown	gnl|CDD|224536
NZ_CP046115.1|WP_154681858.1|4428155_4429151_+|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl|CDD|380511
NZ_CP046115.1|WP_154681852.1|4419972_4421100_+|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC	unknown	unknown	gnl|CDD|236947
NZ_CP046115.1|WP_154681862.1|4433693_4434389_-|porin	unknown	unknown	gnl|CDD|368776
NZ_CP046115.1|WP_154681865.1|4436957_4437419_+|multidrug/biocide-efflux-PACE-transporter	unknown	unknown	gnl|CDD|226610

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046115.1|WP_154681854.1|4422469_4423597_+|oligogalacturonate-lyase	gnl|CDD|291262	pfam14583, Pectate_lyase22, Oligogalacturonate lyase. This is a family of oligogalacturonate lyases, referred to more generally as pectate lyase family 22. These proteins fold into 7-bladed beta-propellers.	0
NZ_CP046115.1|WP_154681871.1|4442367_4443015_-|type-1-fimbrial-protein	gnl|CDD|185109	PRK15187, PRK15187, fimbrial protein BcfA; Provisional.	4.32162e-05
NZ_CP046115.1|WP_154681855.1|4423708_4425052_-|porin	gnl|CDD|374908	pfam16966, Porin_8, Porin-like glycoporin RafY. This is a family of Gram-negative Gammaproteobacteria putative raffinose-like porins.	0
NZ_CP046115.1|WP_154681868.1|4440161_4440863_+|PilZ-domain-containing-protein	gnl|CDD|227868	COG5581, COG5581, c-di-GMP-binding protein [Signal transduction mechanisms].	0.00641421
NZ_CP046115.1|WP_154681866.1|4437555_4438785_+|transporter	gnl|CDD|273283	TIGR00814, membrane_transport_protein_YhjV, serine transporter. The Hydroxy/Aromatic Amino Acid Permease (HAAAP) Family- serine/threonine subfamily (TC 2.A.42.2) The HAAAP family includes well characterized aromatic amino acid:H+ symport permeases and hydroxy amino acid permeases. This subfamily is specific for hydroxy amino acid transporters and includes the serine permease, SdaC, of E. coli, and the threonine permease, TdcC, of E. coli.//added GO terms, none avaialbelf or ser/thr specifically [SS 2/6/05] [Transport and binding proteins, Amino acids, peptides and amines].	1.37776e-146
NZ_CP046115.1|WP_154681863.1|4434635_4435811_-|acetyl-CoA-C-acyltransferase	gnl|CDD|180261	PRK05790, PRK05790, putative acyltransferase; Provisional.	0
NZ_CP046115.1|WP_154681860.1|4430880_4431642_-|2-dehydro-3-deoxy-D-gluconate-5-dehydrogenase-KduD	gnl|CDD|181605	PRK08993, PRK08993, 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD.	0
NZ_CP046115.1|WP_154681853.1|4421116_4422403_+|extracellular-solute-binding-protein	gnl|CDD|224567	COG1653, UgpB, ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism].	1.85442e-59
NZ_CP046115.1|WP_154681857.1|4426672_4427914_-|oligosaccharide-MFS-transporter	gnl|CDD|236549	PRK09528, lacY, galactoside permease; Reviewed.	0
NZ_CP046115.1|WP_154681861.1|4432184_4433360_+|oligogalacturonate-lyase	gnl|CDD|291262	pfam14583, Pectate_lyase22, Oligogalacturonate lyase. This is a family of oligogalacturonate lyases, referred to more generally as pectate lyase family 22. These proteins fold into 7-bladed beta-propellers.	0
NZ_CP046115.1|WP_154681864.1|4435988_4436861_-|LysR-family-transcriptional-regulator	gnl|CDD|223656	COG0583, LysR, Transcriptional regulator [Transcription].	4.27247e-42
NZ_CP046115.1|WP_154681859.1|4429151_4430570_-|sugar-porter-family-MFS-transporter	gnl|CDD|273317	TIGR00879, Membrane_transporter, MFS transporter, sugar porter (SP) family. This model represent the sugar porter subfamily of the major facilitator superfamily (pfam00083) [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	5.26114e-147
NZ_CP046115.1|WP_154681867.1|4438901_4439774_+|oxidoreductase	gnl|CDD|236676	PRK10376, PRK10376, putative oxidoreductase; Provisional.	0
NZ_CP046115.1|WP_154681869.1|4440867_4441452_+|LuxR-family-transcriptional-regulator	gnl|CDD|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	1.20405e-08
NZ_CP046115.1|WP_154681870.1|4441593_4442310_+|EAL-domain-containing-protein	gnl|CDD|183222	PRK11596, PRK11596, cyclic-di-GMP phosphodiesterase; Provisional.	1.59971e-33
NZ_CP046115.1|WP_154681856.1|4425220_4426660_-|sucrose-6-phosphate-hydrolase	gnl|CDD|224536	COG1621, SacC, Beta-fructosidases (levanase/invertase) [Carbohydrate transport and metabolism].	5.67113e-166
NZ_CP046115.1|WP_154681858.1|4428155_4429151_+|LacI-family-DNA-binding-transcriptional-regulator	gnl|CDD|380511	cd06288, PBP1_sucrose_transcription_regulator, ligand-binding domain of DNA-binding regulatory proteins specific to sucrose that are members of the LacI-GalR family of bacterial transcription repressors. This group includes the ligand-binding domain of DNA-binding regulatory proteins specific to sucrose that are members of the LacI-GalR family of bacterial transcription repressors. The LacI-GalR family repressors are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the sugar-binding domain of ABC-type transport systems that contain the type 1 periplasmic binding protein-like fold. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding affinity of the repressor.	1.47536e-86
NZ_CP046115.1|WP_154681852.1|4419972_4421100_+|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC	gnl|CDD|236947	PRK11650, ugpC, sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC.	1.38715e-164
NZ_CP046115.1|WP_154681862.1|4433693_4434389_-|porin	gnl|CDD|368776	pfam06178, KdgM, Oligogalacturonate-specific porin protein (KdgM). This family consists of several bacterial proteins which are homologous to the oligogalacturonate-specific porin protein KdgM from Erwinia chrysanthemi. The phytopathogenic Gram-negative bacteria Erwinia chrysanthemi secretes pectinases, which are able to degrade the pectic polymers of plant cell walls, and uses the degradation products as a carbon source for growth. KdgM is a major outer membrane protein, whose synthesis is strongly induced in the presence of pectic derivatives. KdgM behaves like a voltage-dependent porin that is slightly selective for anions and that exhibits fast block in the presence of trigalacturonate. In contrast to most porins, KdgM seems to be monomeric.	9.08239e-57
NZ_CP046115.1|WP_154681865.1|4436957_4437419_+|multidrug/biocide-efflux-PACE-transporter	gnl|CDD|226610	COG4125, COG4125, Predicted membrane protein [Function unknown].	3.14851e-56

Protein sequences

>NZ_CP046115.1|WP_154681861.1|4432184_4433360_+|oligogalacturonate-lyase
MAKGMRVKLNYEVSRDPDTGAEITRLTPPEVTCHRNYFYQKCFFNDGSHLLFAGEFDGNWNYYLLDLAKAEAVQLTEGPGDNTFGGFLSPDDKSLYYVKNDRTLLEVNLTTLQEREVYRVADDWVGYGTWVANSDCTRLVGIEIAKSDWTPLNDWQIFHDFFHKGPHCRLLRVDLQTGESNVIHEENKWLGHPIYRPFDDHTVAFCHEGPHDLVDARMWMVNEDGSNVRKVKAHAEGESCTHEFWVPNGSALVYVSYLKGQQGRTIYSFDPDTGVNKAVMQMPACSHLMSNFDGTMLVGDGSGTPVDVKDTSGYTIDNDPYLYAFDVAQQAYFRVARHDTSWATVSNSRQVTHPHPSFTPDDSAILFSSDKDGKPAVYIAKLPPQPEMLKA
>NZ_CP046115.1|WP_154681860.1|4430880_4431642_-|2-dehydro-3-deoxy-D-gluconate-5-dehydrogenase-KduD
MILDAFSLQGKVAVVSGCDTGLGQGMAVGLAEAGCDIVGINIVEPTETIERVTALGRRFLSLTADLRQIDGIPQLLERAVAEFGHIDILVNNAGLIRREDAIDFSEKNWDDVMNLNIKSVFFMSQAAAKHFIAQGNGGKIINIASMLSFQGGIRVPSYTASKSAVMGVTRLLANEWAKHGINVNALAPGYMATNNTQQLRADEQRSSEILDRIPAGRWGLPSDLMGPVVFLASSASDYINGYTVAVDGGWLAR
>NZ_CP046115.1|WP_154681859.1|4429151_4430570_-|sugar-porter-family-MFS-transporter
MTSISNDSTTMPRTQRDTRRMNQFVSVAAAVAGLLFGLDIGVIAGALPFITDHFVLSSRLQEWVVSSMMLGAAIGALFNGWLSFRLGRKYSLMVGAVLFVVGSVGSAFATSVEILLVARIVLGVAVGIASYTAPLYLSEMASENVRGKMISMYQLMVTLGIVMAFLSDTAFSYSGNWRAMLGVLALPAVVLIVLVVFLPNSPRWLAEKGRHVEAEEVLRMLRDTSEKARDELNEIRESLKLKQGGWALFKVNRNVRRAVFLGMLLQAMQQFTGMNIIMYYAPRIFKMAGFTTTEQQMVATLVVGLTFMFATFIAVFTVDKAGRKPALKIGFSVMALGTLVLGYCLMQFDNGTASSGLSWLSVGMTMMCIAGYAMSAAPVVWILCSEIQPLKCRDFGITCSTTTNWVSNMIIGATFLTLLDAIGAAGTFWLYTALNVAFIGVTFWLIPETKNVTLEHIERKLMSGEKLRNIGN
>NZ_CP046115.1|WP_154681858.1|4428155_4429151_+|LacI-family-DNA-binding-transcriptional-regulator
MASLKDVAKLANVSLMTVSRALNSPERLKPETLARVQAAIEQTNYVPDLSAKKIRGAHATPNTIGVLALDTVTTPFSVEITLSIEETARAHGWNSFVVNMFSDDSPETIVDLLLSHRPDGIIYTTMGLRQVPLPAKLLTLPCVLANCESLHDPVASYIPDDEQGQYTAVQALLAAGYRRPLCLHLPANHLATVRRRQGLERACREAGINPDTLEHCYMAYGDEHYRDIPAMVLTHIKQQTPRFDSVICGNDRIAFMVYQTLLAHGLRIPQDVAVVGYDNMVGIGDLFLPPLSTVQLPHYEIGRLSALHIINGDSHRDTVRVTSPWLPRESL
>NZ_CP046115.1|WP_154681857.1|4426672_4427914_-|oligosaccharide-MFS-transporter
MMKAHHSHSYPLLSALLFFFFVTWSSSGSLLSIWLHQEVGLKAGDTGIIYAVLSVSALFAQVCYGFIQDKLGLRKNLLWYITVLLILSGPAYMLFGYLLKVNVLLGSIFGGIYIGLTFNGGIGVLESYTERVARQSQFEFGKARMWGSLGWAVATFFAGLLFNINPHLNFAVASCSGLVFFMLLARLRVSSAPHAMQEAVSGGKVTLEDALRLLTLPRFWALVFFVIGTCIYGVYDQQFPVYFSSQFPTLQEGNEMYGYLNSFQVFLEAAGMFCAPWLVNRIGAKNGLIFAGMVMAMRMVASGLVEGPLLISITKLLHAVELPVLLVSIFKYNSLNFDKRLSSTLYLVGFACTSSVIATVLSPLAGYSYEKYGFAQSYLIMGLLVFCTTFISIFLLRSTKSSSDPLVPQTSAI
>NZ_CP046115.1|WP_154681856.1|4425220_4426660_-|sucrose-6-phosphate-hydrolase
MNMTYSISRAEQELQAKHEKLNLRWYPRYHLAARAGWINDPNGLVWFDGWYHAFYQHHPYSTQWGPMHWGHARSKDLLHWEHLPVALAPEGPEDKDGCFSGSAVVDGDTLALIYTGHKFHGDPNDEGNLYQVQCLATSLDGIRFERQGIVVDTPPGMHHFRDPKVWRAGDSWYMIVGARDGDTGQVRLYRSTDLRQWQDAGVLDEAEKEMGYMWECPDFFVLNGKHVLMFSPQGLEAKGYQNRNLFQSGYLLGDWRPGQAFVREGAFVEMDRGHDFYAPQSFLTPDGRRIVIGWLDMWESPQPEQQDGWAGMLSLPRELSLSADNRLQMRPAKEVESMRGAWFPWPVTTLKNQQTTMVENCEAMEAILHWDCANSSAEQYGLSFGDGLRVYVDAQMQRLVLERHYPQYGLCGTRSVPLTEGADLKLRVFFDSSSVEVFVNDGEACLSSRIYPDADKRELALFAWSGSAYLTEAGAWQLE
>NZ_CP046115.1|WP_154681855.1|4423708_4425052_-|porin
MNKIWIGCVLTSLFTPLANAQAPLSLEERLAQMEQRLKATEQRAASAEAEIRALKGQETPAAVVTAAPAKPALQLNDYGELKFYGDVEFNMDGASRTGSLTSVKTSANKNWAPGDKERWDINGRILLGVDGLRKGADGKYAGFSVQPLADINGKMNLDDAAFFFGQQDDWKIKIGRFEAYDMFPLNQDTFIEYSGNTANDLYSDGYGYIYMMKEGRGRSSSGGNFLLSKNIDNWYFEVNTLVEDGSSLFVDHNYHGNALDNRKNVVYVRPVAAWQSGAWSVAAAMESNLVNNAYGYQNQNGRWVDQSSRTGYGMTMSWNTLKTDAENGAVVNLSTAYLDAADEKDFSAGINALWRRVELGYIYAHNKIDQFNMSGVSAECDGDCAILAPGRYDIHTIHTSWQLPNIMDMPNFNIYLGAYASWLDSSAAKSGNTDERYGARVRFKYFF
>NZ_CP046115.1|WP_154681854.1|4422469_4423597_+|oligogalacturonate-lyase
MKGKIIPLKFLHTQDSETGHQVIRMTPPHVICHRNYFYQKCFTRDGSKLIFGGAFEGHWNYYFLDIAAQQAIQLTDGPGDNTFGGFLSADDRALWYVKNNQQLRRVDLASLEEQVVYQVDDEWVAYGTWVANSDDSQLVGIEIKKSDWQPLTDWGKFRAFYFTEPECRLINIDLHSGERRVVLQEKRWLGHPIYRPFDDSTIAFCHEGPRDAIDARMWLINADGSNMRKVRQHQPGESFTHEFWVPDGSALYYVAHQENDPHRYLYSADPATLENRQLMAIPPCSHLMSNHDGSLVVGDGAPHNTGDISLNDPFIWLFDIAAGRQTAVCRHDSTWKVIEGERQATHPHPSFSPDNRWVLFTSDKEGMPALYLAEV
>NZ_CP046115.1|WP_154681853.1|4421116_4422403_+|extracellular-solute-binding-protein
MKKVLLSAAISATLALTALPSMAKDVDLRMSWWGGNGRHQVTLKALEEFHKQNPDINVKAEYTGWDGHLSRLTTQIAGGTEPDVMQTNWNWLPIFSKNGEGFYDLNKMKDVIDLSQFDAKELQTTTVDGKLNGIPISVTARVFYFNDETWKKAGVEYPKTWDELLAAGKTFESKLGKQYYPVVLEHQDTLALLNSYMIQKYNQPAIDEKTKKFSYSKEQWVEFFEMYKKLVDSHVMPDTKYYASFGKSNMYEMKPWIQGEWGGTYMWNSTINKYSDNLKPPAKLELGSYPMLPGATDAGLFFKPAQMLSIGKSTKNPEAAAKVINFLLNSKEGVETLGLERGVPLSKVAVQYLTENGAIKEDDPAVSGLRLAQSLPAKLSVSPYFDDPQIVAQFGTSLQYIDYGQKTVEETAVDFQRQSDRILRRAMR
>NZ_CP046115.1|WP_154681852.1|4419972_4421100_+|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC
MAEVIFNKLEKVYSNGFKAVHGIDLKIADGEFMVIVGPSGCAKSTTLRMLAGLETISGGEVRIGEKIVNNLAPKARGIAMVFQNYALYPHMTVRENLAFGLKLSKLPKDQIEAQVNEAAKILELEELLDRLPRQLSGGQAQRVAVGRAIVKKPDVFLFDEPLSNLDAKLRASMRIRISDLHKQLKKSGKPATTVYVTHDQTEAMTMGDRICVMKLGHIMQVDTPDNLYHKPKNMFVAGFIGAPEMNIRPSQLVEQAGRLHLTVGDGLLPLNDRLQSKVDTHKNQQVFFGVRPEFVSISDEPFVEGSCPGEMVRVENMGHEFFVYLKVADYELTARVPSDEAKPMIEKGLHRTVHFKFDLNKCHIFDAKTEQNISL
>NZ_CP046115.1|WP_154681862.1|4433693_4434389_-|porin
MFARSLALAALCGMSFAASAVTVDLRHEFIDGGKSDKTNADRVSVSHRFANGFGFSVEAKWKSGGENTSQPYSDFIGNGHEESISWQWKADKNFSLTPAFTIESNDSRTIYKPNLRAQYSFDNGFYVAARYRYDYTRYPANAGKDDDKVNRGDAWAGYVFGDWRAELNYVYARSTEGVKRNDNKPYSQEYNLKVAYKLDKNWAPYGELGNVGVNDRSDRQTRFRVGVAYSF
>NZ_CP046115.1|WP_154681863.1|4434635_4435811_-|acetyl-CoA-C-acyltransferase
MKDVVIVGALRTPIGCFQGTLSRHSAVELGSVVVKALVERSGVDPQSIDEVILGQVLTAGTGQNPARQSAIRGGLPNTVSAITINDVCGSGLKALHLATQAIQCGEADVVIAGGQENMSRAPHVLTDSRTGAQLGNSQLIDSLVHDGLWDAFNDYHMGVTAENLAREYGISRELQDAWALSSQHKARRAIDSGRFRDEIVPVTSELNGAPRLVDTDEQPRVDASAEALASLLPTFDLQGSVTAGNASSINDGAAAVMMMSEAKAGELGLPILARIRAFASVGVDPALMGIAPVHATRRCLERAGWKLDEVDLIEANEAFAAQAISVGRVLEWDERRVNVNGGAIALGHPIGASGCRILVSLVHEMIKRDARKGLATLCIGGGQGVALAVER
>NZ_CP046115.1|WP_154681864.1|4435988_4436861_-|LysR-family-transcriptional-regulator
MRYSPEALTAFVESVSCGSFSGAARRLRKSQSTISTAIANLEADLGVTLFDRTSRQPTLTPQGEQVLSYVKAIRAASDRLDELAISLSGNTEARLTFVLSDTLHPDVLEDLLAQFDRRFPHTEFECLIGEDDDVIDLLQKERAQVGLIEARESYPTEIGSIRLPMQTEMAIYVAPQHPLAAQGRATWDELLSWRELRLSTYLENTAEPSRGLVWSAPNYLLLFSMAAQGLGWCILPSALVQEFAGSGSLVALEIAGWPRVISTDLLWNKKAPPGEAGSWLRQHLQKHGRE
>NZ_CP046115.1|WP_154681865.1|4436957_4437419_+|multidrug/biocide-efflux-PACE-transporter
MQQLNAQRKTLTERIIHAISFEGLATLILAPTAAWLMQRSVVEMGGLSVLLATLAMVWNIIYNAIFDRLWPVSRVIRNLRVRALHAIGFESGFIIIGVTMVALVLGVSLIQAFMLEIGFMLFFLPYTMAFNWVWDTLRERVMKVRQQRISARQ
>NZ_CP046115.1|WP_154681866.1|4437555_4438785_+|transporter
MSKIWSKEETLWSFALYGTAVGAGTLFLPIQLGSAGAVVLFITALVAWPLTYWPHKALSQFILSANIAPGEGITGAVNHYYGKKIGSLITGLYFLAFFVVVLIYAVAITNSLAEQLSRHVPITPQVRALLSLGVVLVLNLIFLMGRHVTIKVMGFLVFPLIACFLFLSIYLMGSWQPAYLTSQMQLTSHTFHQIWISIPVMVFAFSHTPIMSTFAIDQQEKYGDRAMGKCKKIMKVAYTLICASVLFFVFSCLLSIPASYIETARNQGVTILSALSMMPGSPAWLAIAGIIVAVVAMSKSFLGTYFGVIEGASEIVKTSLAQAGIRKSRAFNRAMSILLVSTLTFVVCFINPNAISMIYAISGPLIAMILFIMPTLSTYLIPALKPYRSAGNVITLIVGLLCVSVMFFS
>NZ_CP046115.1|WP_154681867.1|4438901_4439774_+|oxidoreductase
MSSVKLSGTATLGDRQVYRLGYGAMQLAGPGVFGPPKDPQTAIRVLQEAVESGVNHIDTADFYGPHVTNQLIRQALHPYSDELCIVTKVSARRDEKGNWLPAMSPAELTQAVEDNLRNLGLEVLEVVNLRSMLDTHGPVEGSLEEPLTTLLELKERGLIRHIGLSNVTAKQVSDAQKLTPIVCVQNQYNVANRHDDPLIDELAAQNIAWVPFFPLGGFTPLQAQELNDVAASLDATPMQVALAWLLQRSPNILLIPGTSSLQHLHENLAAAELILPPEALAILDNLQPRS
>NZ_CP046115.1|WP_154681868.1|4440161_4440863_+|PilZ-domain-containing-protein
MTEGTIKTSKYEIIAIFREELRKQAEIEVFVNNKSTITQLTRVDFAEFHISTTSKIPAGHKVKFILHSDSGKIEFSSVLKKSYASVEGKCHKLAFTLPECIQVVQRRRDPRFRLGHEHDFFCHGRHKNGENYLFEIKDISDGGCALMTKSPNLKFLSHNATLKNAILALAEYGEITVDLVIKNVVMVTLDDNEKSDSYYQISCQFKFRQLNNKKRIEKVLLDLIMEAKRKKRV
>NZ_CP046115.1|WP_154681869.1|4440867_4441452_+|LuxR-family-transcriptional-regulator
MESILLYTDDNIIGRSIHDYMIAKAKHITTLNFQDIVKGVNAPATTTVIINIIHKDIPASTAVSLLNTLRKRLANCAMLVLIVKNELSILFRELINMENLLILNEKSSLSAFDAILSSPQSAIDCRALCTRRKLTARELQVLELVIACNNNKRIAALLKIDHKTVHSHKVHIMKKLEMNSSRIMKSTIVNMHQC
>NZ_CP046115.1|WP_154681870.1|4441593_4442310_+|EAL-domain-containing-protein
MNATLFSDHHLSRSDITVRYVFQKMFSPQGTLVAVECLSRFDRLSISPENFFRYANTGLRESIFMEQLALIEKHKQWFNKNHISATINVDDHILNVLLRPEIKELVERIGCVHFEVTENSNKLLNNALATWNDPQSTTLWLDDFGSGNAGINAIRGYHFDYVKIDKDFFWHLMQKDSGRPLMDALVTFLSRNHHNVIIEGVESEAHKKWLQGMEWFAIQGHYWQEVSIDQLVKEDITA
>NZ_CP046115.1|WP_154681871.1|4442367_4443015_-|type-1-fimbrial-protein
MRDAAQLKNIPRLIQLILLSGALMVSSTWAFETNYERGRVDFAGRVTDISCSVALNGGNNAGSGSVWLAPVSLAEVHERGAGAFMKPQSFTLELSECQLRHCGAADHDAIGLVNVRWVDGFMVNAVSNENAGYLANTRADGARNIFLALSTNDNNTLDKSNKIVPADPLQNRVPLVEKAVEGGVFTYYIGYVTPAPEKATSGPLTSWATWELVYN

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP046115_4	4.4|4281394|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR	4281394-4281425	32	MK416015	Klebsiella phage ST16-OXA48phi5.4, complete genome	33387-33418	1	0.969
NZ_CP046115_2	2.1|3614379|32|NZ_CP046115|CRISPRCasFinder,CRT	3614379-3614410	32	MK416008	Klebsiella phage ST405-OXA48phi1.3, complete genome	4879-4910	4	0.875
NZ_CP046115_2	2.3|3614501|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR	3614501-3614532	32	NZ_CP026278	Klebsiella oxytoca strain KONIH2 plasmid pKOR-0e8e, complete sequence	40937-40968	4	0.875
NZ_CP046115_2	2.3|3614501|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR	3614501-3614532	32	MK714353	Klebsiella phage ST13-OXA48phi12.5, complete genome	38449-38480	4	0.875
NZ_CP046115_2	2.3|3614501|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR	3614501-3614532	32	KY271395	Klebsiella phage 2b LV-2017, complete genome	41071-41102	4	0.875
NZ_CP046115_2	2.3|3614501|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR	3614501-3614532	32	MK448233	Klebsiella phage ST11-VIM1phi8.1, complete genome	39845-39876	4	0.875
NZ_CP046115_2	2.3|3614501|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR	3614501-3614532	32	KY271396	Klebsiella phage 2 LV-2017, complete genome	3230-3261	4	0.875
NZ_CP046115_2	2.3|3614501|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR	3614501-3614532	32	MK448235	Klebsiella phage ST512-KPC3phi13.1, complete genome	39845-39876	4	0.875
NZ_CP046115_2	2.3|3614501|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR	3614501-3614532	32	MK448231	Klebsiella phage ST101-KPC2phi6.1, complete genome	42308-42339	4	0.875
NZ_CP046115_4	4.4|4281394|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR	4281394-4281425	32	NZ_CP035707	Sphaerotilus natans subsp. sulfidivorans strain D-507 plasmid pSna507_unt13, complete sequence	37958-37989	5	0.844
NZ_CP046115_2	2.4|3614562|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR	3614562-3614593	32	NZ_CP030828	Neorhizobium sp. NCHU2750 plasmid pNCHU2750a, complete sequence	224585-224616	6	0.812
NZ_CP046115_4	4.4|4281394|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR	4281394-4281425	32	NZ_CP021031	Rhizobium sp. NXC14 plasmid pRspNXC14a, complete sequence	327334-327365	6	0.812
NZ_CP046115_4	4.4|4281394|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR	4281394-4281425	32	NZ_CP023068	Ensifer sojae CCBAU 05684 plasmid pSJ05684b, complete sequence	1467644-1467675	6	0.812
NZ_CP046115_4	4.4|4281394|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR	4281394-4281425	32	CP006879	Rhizobium gallicum bv. gallicum R602 plasmid pRgalR602b, complete sequence	370259-370290	6	0.812
NZ_CP046115_1	1.5|1924812|32|NZ_CP046115|CRISPRCasFinder	1924812-1924843	32	NZ_CP006991	Rhizobium sp. IE4771 plasmid pRetIE4771e, complete sequence	35452-35483	7	0.781
NZ_CP046115_1	1.2|1924753|31|NZ_CP046115|PILER-CR	1924753-1924783	31	NC_015314	Pseudonocardia dioxanivorans CB1190 plasmid pPSED01, complete sequence	96291-96321	9	0.71
NZ_CP046115_1	1.2|1924753|31|NZ_CP046115|PILER-CR	1924753-1924783	31	NZ_CP030220	Salmonella enterica strain SA20021456 plasmid pSA20021456.1, complete sequence	4237-4267	9	0.71
NZ_CP046115_1	1.4|1924752|32|NZ_CP046115|CRISPRCasFinder	1924752-1924783	32	NZ_CP030220	Salmonella enterica strain SA20021456 plasmid pSA20021456.1, complete sequence	4236-4267	9	0.719
NZ_CP046115_4	4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR	4281516-4281547	32	AP013502	Uncultured Mediterranean phage uvMED DNA, complete genome, group G2, isolate: uvMED-CGR-C14A-MedDCM-OCT-S23-C10	24514-24545	9	0.719
NZ_CP046115_4	4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR	4281516-4281547	32	AP013783	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C14A-MedDCM-OCT-S24-C161, *** SEQUENCING IN PROGRESS ***	8424-8455	9	0.719
NZ_CP046115_4	4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR	4281516-4281547	32	AP013505	Uncultured Mediterranean phage uvMED DNA, complete genome, group G2, isolate: uvMED-CGR-C14A-MedDCM-OCT-S38-C26	24731-24762	9	0.719
NZ_CP046115_4	4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR	4281516-4281547	32	AP013504	Uncultured Mediterranean phage uvMED DNA, complete genome, group G2, isolate: uvMED-CGR-C14A-MedDCM-OCT-S34-C29	23473-23504	9	0.719
NZ_CP046115_4	4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR	4281516-4281547	32	AP014448	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C14A-MedDCM-OCT-S35-C81, *** SEQUENCING IN PROGRESS ***, 2 ordered pieces	15229-15260	9	0.719
NZ_CP046115_4	4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR	4281516-4281547	32	AP013794	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C14A-MedDCM-OCT-S41-C142, *** SEQUENCING IN PROGRESS ***	9197-9228	9	0.719
NZ_CP046115_4	4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR	4281516-4281547	32	AP013796	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C14A-MedDCM-OCT-S44-C315, *** SEQUENCING IN PROGRESS ***	2438-2469	9	0.719
NZ_CP046115_4	4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR	4281516-4281547	32	GU943046	Uncultured phage MedDCM-OCT-S12-C496 genomic sequence	3690-3721	9	0.719
NZ_CP046115_4	4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR	4281516-4281547	32	AP013795	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C14A-MedDCM-OCT-S43-C156, *** SEQUENCING IN PROGRESS ***	7164-7195	9	0.719
NZ_CP046115_4	4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR	4281516-4281547	32	AP013506	Uncultured Mediterranean phage uvMED DNA, complete genome, group G2, isolate: uvMED-CGR-C14A-MedDCM-OCT-S42-C35	10886-10917	9	0.719
NZ_CP046115_4	4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR	4281516-4281547	32	AP013786	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C14A-MedDCM-OCT-S31-C108, *** SEQUENCING IN PROGRESS ***	3357-3388	9	0.719
NZ_CP046115_4	4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR	4281516-4281547	32	AP013503	Uncultured Mediterranean phage uvMED DNA, complete genome, group G2, isolate: uvMED-CGR-C14A-MedDCM-OCT-S29-C22	34098-34129	9	0.719
NZ_CP046115_4	4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR	4281516-4281547	32	GU943055	Uncultured phage MedDCM-OCT-S04-C26 genomic sequence	22931-22962	9	0.719
NZ_CP046115_4	4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR	4281516-4281547	32	AP013785	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C14A-MedDCM-OCT-S30-C161, *** SEQUENCING IN PROGRESS ***	8986-9017	9	0.719
NZ_CP046115_4	4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR	4281516-4281547	32	AP013789	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C14A-MedDCM-OCT-S33-C266, *** SEQUENCING IN PROGRESS ***	2438-2469	9	0.719
NZ_CP046115_4	4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR	4281516-4281547	32	AP013791	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C14A-MedDCM-OCT-S36-C101, *** SEQUENCING IN PROGRESS ***	9988-10019	9	0.719
NZ_CP046115_4	4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR	4281516-4281547	32	AP013793	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C14A-MedDCM-OCT-S39-C151, *** SEQUENCING IN PROGRESS ***	5090-5121	9	0.719
NZ_CP046115_4	4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR	4281516-4281547	32	AP013784	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C14A-MedDCM-OCT-S27-C105, *** SEQUENCING IN PROGRESS ***	12236-12267	9	0.719
NZ_CP046115_4	4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR	4281516-4281547	32	AP013787	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C14A-MedDCM-OCT-S32-C104, *** SEQUENCING IN PROGRESS ***	9988-10019	9	0.719
NZ_CP046115_1	1.4|1924752|32|NZ_CP046115|CRISPRCasFinder	1924752-1924783	32	NC_015314	Pseudonocardia dioxanivorans CB1190 plasmid pPSED01, complete sequence	96290-96321	10	0.688
NZ_CP046115_1	1.5|1924812|32|NZ_CP046115|CRISPRCasFinder	1924812-1924843	32	NZ_CP021128	Rhizobium sp. Kim5 plasmid pRetKim5d, complete sequence	37021-37052	10	0.688
NZ_CP046115_1	1.5|1924812|32|NZ_CP046115|CRISPRCasFinder	1924812-1924843	32	CP007645	Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803d, complete sequence	37001-37032	10	0.688

1. spacer 4.4|4281394|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR matches to MK416015 (Klebsiella phage ST16-OXA48phi5.4, complete genome) position: , mismatch: 1, identity: 0.969

gcgcgccagcgtgccggtcatagctgcggctt	CRISPR spacer
gcgcgccagcgtgccggtcatcgctgcggctt	Protospacer
********************* **********

2. spacer 2.1|3614379|32|NZ_CP046115|CRISPRCasFinder,CRT matches to MK416008 (Klebsiella phage ST405-OXA48phi1.3, complete genome) position: , mismatch: 4, identity: 0.875

gtcttcagaccaggcgagcatatccagaaacg	CRISPR spacer
accttcagaccaagcgagcatgtccagaaacg	Protospacer
..**********.********.**********

3. spacer 2.3|3614501|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026278 (Klebsiella oxytoca strain KONIH2 plasmid pKOR-0e8e, complete sequence) position: , mismatch: 4, identity: 0.875

gccgtgggctaaccgtgcctgcagttttgaat	CRISPR spacer
gccctgggctaaccgcgcctgcagttttgagc	Protospacer
*** ***********.**************..

4. spacer 2.3|3614501|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR matches to MK714353 (Klebsiella phage ST13-OXA48phi12.5, complete genome) position: , mismatch: 4, identity: 0.875

gccgtgggctaaccgtgcctgcagttttgaat	CRISPR spacer
gccctgggctaaccgcgcctgcagttttgagc	Protospacer
*** ***********.**************..

5. spacer 2.3|3614501|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR matches to KY271395 (Klebsiella phage 2b LV-2017, complete genome) position: , mismatch: 4, identity: 0.875

gccgtgggctaaccgtgcctgcagttttgaat	CRISPR spacer
gccctgggctaaccgcgcctgcagttttgagc	Protospacer
*** ***********.**************..

6. spacer 2.3|3614501|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR matches to MK448233 (Klebsiella phage ST11-VIM1phi8.1, complete genome) position: , mismatch: 4, identity: 0.875

gccgtgggctaaccgtgcctgcagttttgaat	CRISPR spacer
gccctgggctaaccgcgcctgcagttttgagc	Protospacer
*** ***********.**************..

7. spacer 2.3|3614501|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR matches to KY271396 (Klebsiella phage 2 LV-2017, complete genome) position: , mismatch: 4, identity: 0.875

gccgtgggctaaccgtgcctgcagttttgaat	CRISPR spacer
gccctgggctaaccgcgcctgcagttttgagc	Protospacer
*** ***********.**************..

8. spacer 2.3|3614501|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR matches to MK448235 (Klebsiella phage ST512-KPC3phi13.1, complete genome) position: , mismatch: 4, identity: 0.875

gccgtgggctaaccgtgcctgcagttttgaat	CRISPR spacer
gccctgggctaaccgcgcctgcagttttgagc	Protospacer
*** ***********.**************..

9. spacer 2.3|3614501|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR matches to MK448231 (Klebsiella phage ST101-KPC2phi6.1, complete genome) position: , mismatch: 4, identity: 0.875

gccgtgggctaaccgtgcctgcagttttgaat	CRISPR spacer
gccctgggctaaccgcgcctgcagttttgagc	Protospacer
*** ***********.**************..

10. spacer 4.4|4281394|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP035707 (Sphaerotilus natans subsp. sulfidivorans strain D-507 plasmid pSna507_unt13, complete sequence) position: , mismatch: 5, identity: 0.844

gcgcgccagcgtgccggtcatagctgcggctt-	CRISPR spacer
tcgcgccagcgtgccggtcatcgcc-cggcctg	Protospacer
 ******************** **. ****.* 

11. spacer 2.4|3614562|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP030828 (Neorhizobium sp. NCHU2750 plasmid pNCHU2750a, complete sequence) position: , mismatch: 6, identity: 0.812

tcctggaatacgaacgtttccagatctgagcg-	CRISPR spacer
tcctgaaatacgaacatttccag-cctgcacgt	Protospacer
*****.*********.******* .*** .** 

12. spacer 4.4|4281394|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021031 (Rhizobium sp. NXC14 plasmid pRspNXC14a, complete sequence) position: , mismatch: 6, identity: 0.812

---gcgcgccagcgtgccggtcatagctgcggctt	CRISPR spacer
atcgtgcgc---cgtaccggtcatagccgcggctt	Protospacer
   *.****   ***.***********.*******

13. spacer 4.4|4281394|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023068 (Ensifer sojae CCBAU 05684 plasmid pSJ05684b, complete sequence) position: , mismatch: 6, identity: 0.812

---gcgcgccagcgtgccggtcatagctgcggctt	CRISPR spacer
atcgtgcgc---cgtaccggtcatagccgcggctt	Protospacer
   *.****   ***.***********.*******

14. spacer 4.4|4281394|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR matches to CP006879 (Rhizobium gallicum bv. gallicum R602 plasmid pRgalR602b, complete sequence) position: , mismatch: 6, identity: 0.812

---gcgcgccagcgtgccggtcatagctgcggctt	CRISPR spacer
atcgtgcgc---cgtaccggtcatagccgcggctt	Protospacer
   *.****   ***.***********.*******

15. spacer 1.5|1924812|32|NZ_CP046115|CRISPRCasFinder matches to NZ_CP006991 (Rhizobium sp. IE4771 plasmid pRetIE4771e, complete sequence) position: , mismatch: 7, identity: 0.781

agttaaca--gacaagcgtctaagccggcttcat	CRISPR spacer
--ttgagatcgacaagcgtctgagcaggcttcag	Protospacer
  **.* *  ***********.*** ******* 

16. spacer 1.2|1924753|31|NZ_CP046115|PILER-CR matches to NC_015314 (Pseudonocardia dioxanivorans CB1190 plasmid pPSED01, complete sequence) position: , mismatch: 9, identity: 0.71

aaaacgaacgcgaccaggggatggagcgttt	CRISPR spacer
gtcgggaccgcgaccaggggattgagcgggt	Protospacer
.  . ** ************** *****  *

17. spacer 1.2|1924753|31|NZ_CP046115|PILER-CR matches to NZ_CP030220 (Salmonella enterica strain SA20021456 plasmid pSA20021456.1, complete sequence) position: , mismatch: 9, identity: 0.71

aaaacgaacgcgaccaggggatggagcgttt	CRISPR spacer
ccagtgaacgtgagcaggggatggagcgggc	Protospacer
  *..*****.** **************  .

18. spacer 1.4|1924752|32|NZ_CP046115|CRISPRCasFinder matches to NZ_CP030220 (Salmonella enterica strain SA20021456 plasmid pSA20021456.1, complete sequence) position: , mismatch: 9, identity: 0.719

aaaaacgaacgcgaccaggggatggagcgttt	CRISPR spacer
accagtgaacgtgagcaggggatggagcgggc	Protospacer
*  *..*****.** **************  .

19. spacer 4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR matches to AP013502 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G2, isolate: uvMED-CGR-C14A-MedDCM-OCT-S23-C10) position: , mismatch: 9, identity: 0.719

ataaaaggtttaaagactcagactgcaaaata	CRISPR spacer
agtatgacattaaagactcaaacggcaaaata	Protospacer
*  * ..  ***********.** ********

20. spacer 4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR matches to AP013783 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C14A-MedDCM-OCT-S24-C161, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.719

ataaaaggtttaaagactcagactgcaaaata	CRISPR spacer
agtatgacattaaagactcaaacggcaaaata	Protospacer
*  * ..  ***********.** ********

21. spacer 4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR matches to AP013505 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G2, isolate: uvMED-CGR-C14A-MedDCM-OCT-S38-C26) position: , mismatch: 9, identity: 0.719

ataaaaggtttaaagactcagactgcaaaata	CRISPR spacer
agtatgacattaaagactcaaacggcaaaata	Protospacer
*  * ..  ***********.** ********

22. spacer 4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR matches to AP013504 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G2, isolate: uvMED-CGR-C14A-MedDCM-OCT-S34-C29) position: , mismatch: 9, identity: 0.719

ataaaaggtttaaagactcagactgcaaaata	CRISPR spacer
agtatgacattaaagactcaaacggcaaaata	Protospacer
*  * ..  ***********.** ********

23. spacer 4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR matches to AP014448 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C14A-MedDCM-OCT-S35-C81, *** SEQUENCING IN PROGRESS ***, 2 ordered pieces) position: , mismatch: 9, identity: 0.719

ataaaaggtttaaagactcagactgcaaaata	CRISPR spacer
agtatgacattaaagactcaaacggcaaaata	Protospacer
*  * ..  ***********.** ********

24. spacer 4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR matches to AP013794 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C14A-MedDCM-OCT-S41-C142, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.719

ataaaaggtttaaagactcagactgcaaaata	CRISPR spacer
agtatgacattaaagactcaaacggcaaaata	Protospacer
*  * ..  ***********.** ********

25. spacer 4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR matches to AP013796 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C14A-MedDCM-OCT-S44-C315, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.719

ataaaaggtttaaagactcagactgcaaaata	CRISPR spacer
agtatgacattaaagactcaaacggcaaaata	Protospacer
*  * ..  ***********.** ********

26. spacer 4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR matches to GU943046 (Uncultured phage MedDCM-OCT-S12-C496 genomic sequence) position: , mismatch: 9, identity: 0.719

ataaaaggtttaaagactcagactgcaaaata	CRISPR spacer
agtatgacattaaagactcaaacggcaaaata	Protospacer
*  * ..  ***********.** ********

27. spacer 4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR matches to AP013795 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C14A-MedDCM-OCT-S43-C156, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.719

ataaaaggtttaaagactcagactgcaaaata	CRISPR spacer
agtatgacattaaagactcaaacggcaaaata	Protospacer
*  * ..  ***********.** ********

28. spacer 4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR matches to AP013506 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G2, isolate: uvMED-CGR-C14A-MedDCM-OCT-S42-C35) position: , mismatch: 9, identity: 0.719

ataaaaggtttaaagactcagactgcaaaata	CRISPR spacer
agtatgacattaaagactcaaacggcaaaata	Protospacer
*  * ..  ***********.** ********

29. spacer 4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR matches to AP013786 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C14A-MedDCM-OCT-S31-C108, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.719

ataaaaggtttaaagactcagactgcaaaata	CRISPR spacer
agtatgacattaaagactcaaacggcaaaata	Protospacer
*  * ..  ***********.** ********

30. spacer 4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR matches to AP013503 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G2, isolate: uvMED-CGR-C14A-MedDCM-OCT-S29-C22) position: , mismatch: 9, identity: 0.719

ataaaaggtttaaagactcagactgcaaaata	CRISPR spacer
agtatgacattaaagactcaaacggcaaaata	Protospacer
*  * ..  ***********.** ********

31. spacer 4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR matches to GU943055 (Uncultured phage MedDCM-OCT-S04-C26 genomic sequence) position: , mismatch: 9, identity: 0.719

ataaaaggtttaaagactcagactgcaaaata	CRISPR spacer
agtatgacattaaagactcaaacggcaaaata	Protospacer
*  * ..  ***********.** ********

32. spacer 4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR matches to AP013785 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C14A-MedDCM-OCT-S30-C161, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.719

ataaaaggtttaaagactcagactgcaaaata	CRISPR spacer
agtatgacattaaagactcaaacggcaaaata	Protospacer
*  * ..  ***********.** ********

33. spacer 4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR matches to AP013789 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C14A-MedDCM-OCT-S33-C266, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.719

ataaaaggtttaaagactcagactgcaaaata	CRISPR spacer
agtatgacattaaagactcaaacggcaaaata	Protospacer
*  * ..  ***********.** ********

34. spacer 4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR matches to AP013791 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C14A-MedDCM-OCT-S36-C101, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.719

ataaaaggtttaaagactcagactgcaaaata	CRISPR spacer
agtatgacattaaagactcaaacggcaaaata	Protospacer
*  * ..  ***********.** ********

35. spacer 4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR matches to AP013793 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C14A-MedDCM-OCT-S39-C151, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.719

ataaaaggtttaaagactcagactgcaaaata	CRISPR spacer
agtatgacattaaagactcaaacggcaaaata	Protospacer
*  * ..  ***********.** ********

36. spacer 4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR matches to AP013784 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C14A-MedDCM-OCT-S27-C105, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.719

ataaaaggtttaaagactcagactgcaaaata	CRISPR spacer
agtatgacattaaagactcaaacggcaaaata	Protospacer
*  * ..  ***********.** ********

37. spacer 4.6|4281516|32|NZ_CP046115|CRISPRCasFinder,CRT,PILER-CR matches to AP013787 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C14A-MedDCM-OCT-S32-C104, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.719

ataaaaggtttaaagactcagactgcaaaata	CRISPR spacer
agtatgacattaaagactcaaacggcaaaata	Protospacer
*  * ..  ***********.** ********

38. spacer 1.4|1924752|32|NZ_CP046115|CRISPRCasFinder matches to NC_015314 (Pseudonocardia dioxanivorans CB1190 plasmid pPSED01, complete sequence) position: , mismatch: 10, identity: 0.688

aaaaacgaacgcgaccaggggatggagcgttt	CRISPR spacer
ggtcgggaccgcgaccaggggattgagcgggt	Protospacer
..  . ** ************** *****  *

39. spacer 1.5|1924812|32|NZ_CP046115|CRISPRCasFinder matches to NZ_CP021128 (Rhizobium sp. Kim5 plasmid pRetKim5d, complete sequence) position: , mismatch: 10, identity: 0.688

agttaacagacaagcgtctaagccggcttcat	CRISPR spacer
ctgagatcgacaagcgtctgagcaggcttcag	Protospacer
    .*. ***********.*** ******* 

40. spacer 1.5|1924812|32|NZ_CP046115|CRISPRCasFinder matches to CP007645 (Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803d, complete sequence) position: , mismatch: 10, identity: 0.688

agttaacagacaagcgtctaagccggcttcat	CRISPR spacer
ctgagatcgacaagcgtctgagcaggcttcag	Protospacer
    .*. ***********.*** ******* 

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	2375438 : 2389518	19	Klebsiella_phage(23.08%)	integrase,holin	attL 2378118:2378133|attR 2400071:2400086
DBSCAN-SWA_2	2457315 : 2487419	24	Klebsiella_phage(20.0%)	tRNA,tail,holin	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP046115|2375438:2389518|DBSCAN-SWA
ATTATTTACCGTCTTTACGCCAGGCATCGGCGGTAAGCGCCTCGCCAAAATGGCCGGCAATAAGACGTTTAGTCAGCTCGTGTAGCGGAGACGCCAGAACATCGGCGGTGCTGCCGCGCTCGACCACTTCACCGTGATGCATCACCAGTACCTGGTCGCTAATATGCTTCATCATCCCCAGATGCTGAGTCACGTAAATGTAGGAAATACCCTGCTTTTCCTGCAGCTCCAGCATCAGGTTTATCAGCTGCGAACGCATAGACATATCCAGCGACGCCAGCGCCTCATCGCAGACAATCACTTTCGGACGCAGAATCAGTGCCCGCGCGAGGCCCAGACGCTGTTTTTGCCCCGGCGCCAGCATATGCGGATAGTAGCTGACATGGTCAGGCAGCAGGCCAACCATGCGCAACGTTTCGATAATCTGCTTCTGCCGCGCCTCTGGCTCGAGGTCGGTATTCAGACGCAGCGGAAAATCGAGGATTTGCGAAATACGCTGCCGTGGGTTGAGTGATGTCGACGGATCCTGAAAGATCATGCGAATCTTCTGGCTGCGGAAAGAGTAATCACCAAACTCCAGCCGATGGTCATCAATCAGCAGTTCGCCGGTGCTGGGTTCGACCATTCCGGCGAGCATTTTCGCCAGCGTTGATTTGCCGGAGCCGTTCTCGCCGATGATCGCCAGCGTCTGGCGTTCACGAAGGGTGAAGCTCAGCGGCTTAACGGCTTCTACCGTTTGCCGATGAAACCAACCGGTACGGTAGCGAAAGGTCTTACTCAAATTGCGTACTTCAAGCAACGTTTCGACCATTTCACTCTTTCTCCATGTTCAGCGGGAAATGACAGGCATAGAGGTGGTTGCGCGCGCCCACCAGGCGTGGCGTTTCGATACATTCGCGCTGGGCGTAGGGGCAACGGGGCCCGAGGCGGCAGCCGATAGGCAGTTGTTCGAGCAGCGGAATAGCCCCCGGCAGGGTGTTGAGCCGACTTTTGTGTTGCATGGCGCTACCGAAGTCCGGGATCGCCCGAATCAGCGCCTGCGTATATGGATGATGAGGAATGGTCACCAGTTCTTCGCTCGGCGCGCTTTCCACCGTTTGCCCGCAGTACATGACGTTAATTTTGTCCGCCCATTTACTGAGCATCTGCATATCGTGGCTGATTAGCAGAATCGTGGTGTTGTTATTTTGGTTCAATCGCGTCAGCAGGCGAATAATTTGCGCCTGAGTCGTCGGCTCCATGGCGTTGGTCGGTTCATCGGCGATAAGCAGGCGAGGCTGGTTTGCCAGCGCAATAGCAATCATGACCTTCTGGCACTCTCCGTCCGTCAGCTCGTAGGGAAAGCTGCGCATCGCATCTTTATGATCTTTGATCCCCACCCGGTGTAAGAGCTCAATCGCGCGCCGTTTACGCCAGCCAAAGCGCTGCCACCAGCGTCCTTTAAAGGTCCAGCCGGGAATGTTCTGCGTCAGCTGCTGGCCGATTCGTTCAGAAGGGTCGAGGCAGGACTGGGGCTCCTGAAAGATCATCGAGACGTTATGGCCCACCAGCTTACGCCGCTCGCGTACTGACAGGCGCAGCAGATCGATATCGTCGAAACGCATGCGGTCGGCGGTCACCCGCCAGTTGTCTTTGGTGACGCCGCAAATTGCTTTGGCAATTAAGCTTTTACCCGAGCCGGATTCTCCGACCAGGCCGCGAATTTCCCCTTCAGCCAGGGTCAGGCTGACGCGGTCGACGGCTTTCACCCAGCCTTCATTGGTTTTAAATTCAATCGTTAAATTACGAATATCGAGTAACGGCATTATTCCACCCCGGCGACGATTGCGCGGCGGATCCCGTCGCCCAGCAGGTTAACCAGCAGGACGCTTATCATAATTGCCGCGCCCGGCAGCATCACCGTCCACGGTGCGACGTAAATCAGCTCCAGCGCATCGCCGAGCATTGCTCCCCATTCAGGGGAAGGAAGCTGAGCGCCGAGGTCGAGGAAACCCAGCGCGGCGATATCCAGGATCGCCATCGACAGCGCCCGGGTGATCTCGGTGACCAGGCCAGAGGTGATATTCGGCAGCACCGCGAACCATAAAATATTCAGCGTCGACGCCCCGTCGAGGCGCGCGGCGATGACGTACTCTTTTTCCAGTTCATCATGCACCATGCTGTAAACCGACCGCACCATGCGCGGCAGGAGCGCCAGCCATACGGCAAACATTGCGTGGCTAAGATGCGGGCCCGCGAAGGCGACGACGATAATCGCCAGCAGCAGGGAGGGAATCGACAGCAGGGTGTCGAGAATATGGTTCATCACAGCAGAACGCAGGCCGTGAGTCGCACCGGCAATCACGCCAAGTACCAGGCCCAGCAGAGAGGCGCCCAGCGTCACTACAAATGCCCCGCCGACCGTTGGCGCCGCGCCGCTCAGCAGACGGCTAAGAACGTCGCGACCCAGATCGTCAGTACCAAGGAAGAATGACACCTCACCGTAGCGCGACCATGACGGCGGCAGCAGCTGATAGCCAAGAAACTGCTGGTCGATGCCGTAAGGCGCGAACCAGCCGCCGAAAACGCACAACAGTACCAGAGCCGCACAGCCGTACAGGCCGACCATAGCGGTAGTATCACCGTAGAATTTTCGCCATACGGTGCGCAGCGCACCCGGCGGGCGCTTCTCCAGATAGACGCTATCGTAGGGCATATAAACCTGTTTTATGTTTGTTAATCATGATTGATGTCTTTTAAAATTCTTCAATACCAACAACACGTTACTTCAATTTTGCGCTTTAAGATTCTTTATTTTGCATTAATTTGAAGGTTATCAATTTACGTATAATGTGTACACTGATGTGTATATCATCTTCCGGAGTGTACACATTGCTTACCGACACAAAACTTAGAAAATCTCTTGGCAAAAAAAGAGACAAAATTGAGGTCATTTCAGACGCTCACGGCTTGAATGTCAGGTTGTCTACTTCCGGCAGTATAACATTCTTTTATCGTTACAGATGGAACGGGAAAGCCGTTCAGCTGACGATTGGCGATTATCCAACCATATCATTATCTCAGGCCCGAGAGCGCCGGCAGCAGTTCAGGGCGTGGTTGACGGAAGGACTGGATCCGAGACGGAAAACAGTGCTGGAGAAACAGAAAAAAACAGAAGCACTGACAGTTAAAGAAGCGTTCGACTACTGGGAAAAGTATTACTGCATTCCAGAAGGACTGGTCAAAATAAAAGTTAATCGCCGGGACTTTAATAATCATATCGCTCCTGTGCTCGGTGACATGATTGTTGACCAGACAACGAAAGCACACTGGCTAAGCCTTTTTGATGATATGGGAAGAAGGGTGGTTACCGGTCAGATGCTGGGTTTAATGCAGCGTACATTCCGTTTCTGCTCCAACAGAGGAGTTATTAACGTAAACCCCATAGAAAGCTTAAGGCGTTCTGACGTTGGGCTTACTGCTGCGGTTAAAGATCGCTGGTTAAGTGACGAAGAAATCAAAACGGTCTGGAATACGCTGCCGGAAATGAAGTACAGGCAGCAGCTGATTATGAAGTTTCTTATCCTGACCGGTTGCCGGAGTACTGAGATAAGAACAGCTAAATGGGAATGGTTTGATTTCCAGGAGGGAACCTGGACTATTCCAGCAAGTGATTACAAAACCGGTAAGTCAGTAAGGCGGGCGCTACCTGAAGCGGTGGTCAACATGATGAAGACAGAAAAGGAAACATCCGTCTCAAATCATGTTGTGACACTGTCACGATACAAAGGGCCAGAAGACGATCGTCCTCCGCAGCAACCCAACGTTGCCTTGTTCTCGGCTCAAATCATAGCCAAAACGGGAATGAAAACGTGGTCGCTTCACGACCTTAGAAGAACAATAGCAACGCGCCTTTCTGAATTAGGCGCGCCGCCACATGTGATTGAGAAATTGCTTGGTCATCATATGTCTGGGGTCATGGCGCGGTATAACCTGCATGACTATCTGGATGAACAGCGGCATTGGCTTGCGGTATGGCAGACTCATCTTGAAAAGCTGATTGGTCAGCCTCTGGTTTGATACCCACGTTATCTTCCCAGGCCAGAAGGTCTGAAAGTCTCCACCTCTTAGGACTGCCGTTTATTTTCGGCTTGGGGAATGGCTGAGAAAAGTAGGCCGGCATCCGGGAGAGGGTACTCCAGAAATACAGCGTGCTGCGTGAAATTTTGTACCTGGACAAAACGTCATCGGTTATCAATATCTCATCTTTAAAATGCGAGGTGTTATTCATAAAAAACCTTTAATTAGATTGTCCTGGCAGATGCTGCAGCCTGCGTGCGCAGTTCATTGCTGTGGCCACATAACTGCATTTTCTGTTTACTACCTCAACCGTAATCTTTGAGCCATTAACCTCAATGGTGTAGGTCCGCTTTGTCTTCTGACGTCCATAATCGCCGTATAGCTCAACGTGCTTCGCCAGTGCCGTTTCGCAGGCCTGGCGTCCGAGAGGAGATTGCTTGCTTCGGTTTATTAGTCGCATAAACATTCCTTAATCGGGAGGGCACCCCTCCCAATCTGGTTAGCCCACGTATTCCGGTTTCATGTCGTCAAGGGTGATGCGGAACTGGTCATACAGTTCATCACCAAGATGGCGGCGCGATGAGGTCAATGTGCTTTCAGCCTTCGTGAATAAAACTTCGGCTTCTGGATCCCCAGGGTTAGGAAGAGAATTTATTGCGGCCTCAACTTTGTTCTTCGCATCAACCATGAAGTAGCGCTGCACGGCTTTACCTTTCAGTTCGGTGAAGAGAACAGTACTGGATGGTAACCGGACTGTATACCGATATGCGCGCAAACGGCCTCAGCGATTCAGAGCTACGTCGTAAAGCATCGGGTGAGCTGTTGCGTATGGTTCGTCGCTTGAACGCTGGAGAAACGATTCCAGAACCGGTTAAGCAGATCCCAAAACTCGGCGGACGTCCGCTGAGTAACGAGCAGGGATTAAACAAAATCGCGGAGATCCGCGCGAAGTTCGGTCTGGGGAGAGGACGGAATCATGGCTAACAAATCACGTGAACAAAAGCAGGCCTGCGTCCAGGCGATTATCGAACTAACCCGCGAGAAAGGGCGCCTGACGGTGAAAGAAGCTTGTGCAGAACTACGCATGTGCCGGGATACAGCTGGCCGGTATTTCCAGGCTGCAGTCAGAACCGGGAAGGTCATTCGCTACGGGCGTCTTGGTTTGTTCCGCGACCTGCGGGCGACCATTGATTTTGACCTTCAGAGATTCAGTCATCGGAAAAATCCTCAGCACAACGAAGGAATGGGTGAGGGCTAACAAATGACCAGCAAATTAATCAGAGAGCGCATTGAGCTAATCGCTAACTTTCATCGTGCAATGACACTGCCGCCGTCTCATGCTGAAATTGAAGAATTGGCGCGCATGGCGCTGGCCGCAATGGACGACGCCTATGACTTAAGGCTCTATTGCTGAGGCATTGGTGAGGGCTAATTTACCTGAATTATGTCAAAAGAAGGATGTAGCCGCCTGATGTATTATAAAGCTGAGAATGCGACTGTGTTTGAAATTATCGTTTGAAATTATTGAATTAAATTCGCGTGGTGCGCTAATTAATATGTGTTTTAGTTTAAATGATTTGGAAAGTTCTCAATTTGAAAATAGTTGAATCTTTACTCCATTAAAGCTGCTATTGTCTTCTGCAAAATGGAACCATCAAGTACCGGAGTCTTCTGTTACTTGATTTTTAAGTCTTTTACATAGGGATGACTGAGGATTTATCATGGCAAATGATTCACGAGGAAATGAGGTGGTTTTCAACCGTGCATATCTAAACTTGTGCTCTGAGAACAAGAAATTAAGTCCGTTGGTTATAGTGAAGAAAATTAAAGAGCACAATATTGTTGAATGTTTTTCTTTTGGTCTTAAGGGGGCGATAGATATTGAGTCAAAATGCCTTTTTTTGCGTTATAAATATCCGTGGCCAGATTTTGAAATTGAACTGGTTAGAAAAAAAGGAGGTGATTATGAGTTCATGCTCTTTCATAATGATTTTCTTAAGGGTATTGACAATTAAGACATTTATAATGATTTTTTAATAAAAATGGATTTTCCTAGACTATATGACTTAGGCATCTTTTTTCTTGAACTTGTCTATAGATAACATTCAAAGAGTATGGCGCACTTGTCCGAGGCTTCTATCAAATAATTGTACTGTCAATCGCACTTACATTTGGCCTCCATGTATTTAAAAAAGTGTACTTCTAAATGACTCTTTTGAACTCACACGAGTTGATTGAATTTTGTTCATCGCGATTTATGCTCCTGCCCATATATAAAGCTCTTGTCTAAAAAGACTATAAAATCAACCCGCTACGGCGGGTTTTCTTTTCTCATTACTGACAATAACTAACGATTTGTGCTCTTAAGTTATTGCTCATTCAGTGAGTTAGGTGTACTGTGTATTTATACAGTATTTTCGCAGGAAGGGAGACTATGAGAATCGAAGTAACCATCGATAAGAACAAGAAGTTGCCTGAAGGTGCTTTAGCGGCGTTGCAGGAAGAACTGATGCGCAGAATTGATGAGAAGTATTGTGATTTCTCGCTGTCACTTCGCCGCGCCAGTATGGATGGTCTCAGCGTTCTTGGTGGTGATAAGGGCGACGAAGAACGAATTGAGCAAATTCTGCCAGAAACCAAGGAAACGTCTGACGGCTGGTTTTATTGAGTAAATTTATTTTGGTGGCGGCCTTTCTCTCAGAGCATCGCGTTCGCGTTACCCTTGATGCTGCTAACCGGTATTGATTATGGTGTTGTGTTCGGTGCGTTTGCTGGAGCGGTGTTTTATGTTGCCACAGCGGCAAATGTGAGTCGTATTCGTTTGAGCGGTTACTTCCTAACTTCATTTATTGTTGGTGTTCTGGGGGCCGGTCTGGTGGGTTCGAAGCTTACAAGCTGGACAGGATACCGCGAGCGACCGCTTGATGCCCTGGGAGCTGTATTAATCTCTGCTCTAATCATAAAAGTGCTCACTTTCCTGCATAGCCAGGACCTTAATAGCTTGTTCAATATGCTGACCCGATTTCGGGGAGGGGGGTCAAGTGGTAAATGATCATTCAGCGCTGGCTAATTCCATCATATGTGCCGTTATCGTGCTTGCCTTGATGTTTTATCAGCGAGGGAACGCGCGCCACCGTCCTGGCATATCTGTGCTGGCTTATCTGATGGTGCTGGTTTATGCCAGCATCCCTTTTCGTTTCCTGTTTGGCCTTTACGAGTCATCAAATTGGCTTGTGGTGATGGCTAACATTCTTATCTGCGGCGCGGTTCTCTGGTTCAGGGGAAATGTTGCCCGCCTGATAGATGCATTGAGGAACTGATGAACCAATCACAATTTCAAAGGGCGGCTGGTATTAGCGCCGGATTAGCTGCGCGCTGGTTTCCGCACATTGATACTGCAATGAACGAATTCAGAATCACTAGTCCTCTCGATCGAGCGATGTTCATAGCGCAGTGTGGACACGAAAGCACGTCATTTACCCAGTTGGTCGAAAGCTTTAACTATAGTGTTGCCGGCTTGGCTGGTTTTGTGAAGGCAAAGCGCATCACTCAGGACCAGGCGAACACTTTAGGACGTAAAACTTACGAAAAAGTTGTACCGCTCGAACGTCAACGAGCGATCGCTAATCTGGTCTACAGCAATCGCTTTGGCAATCAGGCTGCAGGCGATGGCTGGAAGTTTCGCGGGCGTGGAATTATCGGGATCACCTTCCTCGATAATTACATGAAGTGCGGTAATGCACTGAAACTGGATTTAGTCAGCAATCCTGAGTTACTGGAGAAGGATATTAACGCAGCCCGCAGCGCTGCCTGGTTTTACACCTCAAAAGGGTGTTTGAAATATCTAGGTGATTTAGGGCGCGTGACCCAGATTATCAACGGTGGACAGAACGGTATTGATGATCGCCGTGCACGTTTCCTGAAAGCAAAATCGGTACTGGTGGGATGATCATGGGAATAGAAGCTATCGCGGGGCTGGTGGCCATTCTGTTTGGTTTAATAGCTGGCGCTTTCGGTATTGGACATGCTCGCGGCACAAATAAAGCGGAGTCCAAAGCCAAACAACAGCGTACCGAAGAGCACGCCGCTGCCAGCATCGCCGCGGCAGAGCGAAAAGCTGAAGTAACAAAAGAGGCCCGCGATGTTGAAGAGAGCGTTAAACGTATGGGCAATGTCGATGTTGATCGCGAGCTGCGCGAACAATTCACCCGCCCCGGTGGTGGTTGATACCGCGTGCAGTTGGGTGCGGATCATCTACCTGACTGATCATGATATCGACGCGCTGGACATGCAGACGAAGCGAGACATTCTGGCGCACAACAAATCAGTGCAGGCTAACTGCCCGCAACCAACCGAAAAGGCTACGAAATGAGCGAAGCTAAACCGCAGGACGGCAGTACCGTTAAGGGCTACCGCACATTAACCACGGGCGACATTGAGCGGATGAATCGCCTGAAAGATGTGAGTCGTCACTTTTGCAATCTTCTGGATACAGAGCACAATTCCACTATGGATGGAGTGGTTAAAGAAGAGTCCGAGCGTAATGAGGCGTTACGTTGCCTTGATATTGCTCGCACCAAAATGCAGGAAGCCTGTATGTGGGCGTGTCGAGCTGTAGCGCGCCCTGATGCTGATTGTTGAGTGGTTTCGGTTACTGAAGCCTAAGAATGTACTTAAGCTTCAGAAAAGCAGTCAATCAGTTACTTGATAGGTTTACTTTCTGAGGGAAGGAAAATATTTCCGCAGTATGGGCAGATCAATGTTATATCGTTTTTAATTCTCGACAGGCTATATGTGGACTGGCGAGAGCAGTGAGGACAGGTGCTTTTTACAGGCCTGAGTGTACGTATCTTGTCTTTGAGTATAGACATGGTTTTTATCCTCGTGAGTGATTGCTAACCATACACCACAGGACAGTAAATAGCTCACTTTTTAACCTTTATTTTTTTGTGACTATTTTTGTTTATACGGAAGATGGCAACGAAAGATTAAAGCTAATTTCGTCAGAGCAAGGCCATCGCACCTGTTCGATGGCGAGTGAATCGCTTAATGTTTTTTTAAAGATTTTAATTGTGTAAGCGTGATAACCCCTTGCAGGACAATCATCTGTCTGGCCAGACTAATTGAATAGTAATTATCGATTAACAAGAAGAACTGCCAATATTGCGTGGTTGCTGGTATGAAAAAAAATGAAACACACTACTCTCATTGCACCTCCGTCCCAACACCAGTCTGTCGGAGGTCAGTTACTCATTTAGATACATCTCTCCCGGTGGCTCCTGAGAGTTTATTTAATCGATAACTGTGCACGACAAAAGGCCGCATCTCTTTTGCGGCCTTTTTCATAGCCATCACACAGGCCGCTATTCGTGTAGGGTACAGCAAGAAAACCGCCGAACAGAGTGATTATTAGCTTCCTTCGGGCATCCAAAAGACGGTAATTGCTGGTGGTGTAGTGCTGGTCAGTATCGTTGATACAGTAATGCCGGACAGCGTAAAGAAAGACAGATAAAAAAATCCCGCCAATTTTGAGCGGGAATGATGTTAATGATTATATGAAGATATGGATAGTACTACGTTAGTGCGTGCACCGAATCCGAAAACGAAGAGGTAAATCATGATTTTCTGTGTCGATAGAGGCTTCAGAAACCAGTGCATGCTAACTATCCAAGGGAACCTATCAATAATGAGTAAGCTCATGATGGTCGATTAACGGATCATGTGAGGGTTGTTCGTGATAAAATTCAAGCGGTATTGTTTCTTAAAGGAATTCGTGATGTGGGCGTGCTAATTGACAGTGCCCTCAAAGGCTATCTCTTTCTTTTATTGGATATGTGGCCGGTGCTGCTTGTTGCTTTCGTAGGGCTAGCTTTCTCCTTTTATGGTGTTTTAATGCCGAAAACAGCAATCACTTTACTGTTACTTGCTGTAGTAATCGGAATTGCCGGAGGGATTTATGCATAGGACATGCCACGATACTTTCTGACTACCTGTGCTTCGCAAAATCAAGTTATGAGTTCAGAGCCTCGCAATAGCGGGGCTTTTTATTACCAGAAGAAGAAGGAAATACCATGTTTACAGTTAAGACTATTATCAACGGCGTGACCCACATCTGCGAACAGCCGAGTGTGACCATTGCCCGCGCGGGGTGTGAGCGTTTCGACGATATTCTCTTGCAGACAAACGATCACTCAAACCCTGATTTCGCTATCTGGCTGCCAGGTGTCTATTCAGACCCACAATGCACAGATGCGCTTCAGGAAGAAGAGTTAATCGTCAGCGAGCGCGAGGGTGTTCTGGATGAAGATGCCATTGCCATTCTGGTAGAAGACTTCGAAAGCCCTGAGCACGCAAAGCGCAAGGCATTCGACGGTGTTCGATACCAGTTCATCTATCCCGGCGACCAGGTATATGTGATGAATTCCCACGGCTCAACCATCGAAACGGTTAAGTAAGGCATTACAGCAGGCATTCACTGAGTGCCTGTGATAATGCTAAAGTATCCGAGGAAATGCGACAGAGGATTTTGCATGAAAATAGACCATGAGTATTTGAAGGGGTTGCTAGAAGCTTTTGAGTGTTCTGATAAACCAGAAACAGATATACGACATTTGCATGATCTCGGATTTAGTTATCAAACCACAGAGTTTTTATTCCATATGCGCTTGTTGGATGATCGCAACTTGATAGCAAGAACTGATGGGCGTAGTGGGTTTGGATTCTCTGAATCAGCAGATGACGGAGGTTCTTGGTCTGTTTTACCCCTACGTCTCACAGCAAACGGACATGATTTTTTAGAGGCTATACGGAATAAAGAAGTTTGGGCAACATTAAAAACAAGTTTCAAAGATGCAAGTATCGGGACATTAGTAACCGTTTCTAAAGAATTGTTTAACAGAATACTTGCGAAGCAACTGGATAAATATATTTAATCACTAGCAGTATGATTTTAATAGCCTCGTTTATGCGGGGTTTTTTTATTGGAGTTTATATGCGGCTGACAGTTCTGGACGATGATCCCGGCGAATATATAACACCAGGCAGCGAACGTTTTAATCTATATCACTATACCCCTTAATTCCTATCGTTTTTTTGGAGAACCAGATATGCCTTTGTCACAATCGAAAGTTTCAATCGCAGGTAATTTATTCACCAACTCTGGCACAAGCTTGGTTGTTACAGCTGCCGGTACTACTGTTCAGAAAGAGCTTGATGGTATCTATAAAATAGTTAGTGTTAAGGACTATATGACTGACGGTTACAGTAAGAACACCACAGTATACAGGTATAAAGTTTGGACATAACTTAAATACCACTGGTGGCGTCTTTACCGGAGGAGTGATTAAAGCTGACTCAAACATTTATGGTAAAGGATTGGTCGTGTCAGGAGGTATGGGGGAGGAGGTACCAACTACACCCGGGTAACGTGAGCATCAGCGCTGATGCCGTTGCTGTTTCCGGGGATGCAATCTCGCTTATCGGGCAGACGTCAGATGATGATGAAGATGACGACACGTCGATCCCTGAATCATGGAGTACCGCCGTTCATTTGGTCTGAAAGTCGCAGGGAAAGCGCAGGGTGCGCCGTATGACCCTGGCGCCGTGCCATCGACTAACCGCCGCGGTCGGCTGACCAGTCCGACTATCTCTACTCCATCCGGTTCTTTTTCTGCTGGCGACTATTACAGCTACGAAGCATACAACGTCAACTCCAGCGTTTCGGAAACCGTTCCGGGCAACTGGAACGGCCAGTCCGTCTATCTCGGCGATCTGCTGGTCTATGACGGCACCAGCTGGCGTATTCAGCGTTCCCCTGGCTCAGGAGCAGCGCGAAAGAACGATACCTGGTATCTGGTCACCTCGGCTGGAACATTTGCAGGAATGACGCTCTCTCCTGGTGACGCACTGTTATTCCTGACCTTGCAAACCGCAGGCGGTGGATTCCTGCAGCCACAATTTGCTGCTCTGAACACTACCAGTGATCTCCTGCTTTATGGCGGGGAGTTTTCCCCGGCAGCAGGCTATCCGGCGTCAGACCGTCCGAATGTGGTTTACCAGGCATCTGCCAGTGGGAATACAGGCGGGGAAAGTTACACGGCAGGTGACTACGCAATATTTGACGGCATCAGTTGGGTGCGAATTGCGAATGATGAAGCCGTGACGGTTCCAGCCGGGCAAAGTATCAGCCTGCGATGTGCTGCGAATGCGGATGAGTGGGAATTCCGGCGCGCGGATAAAGAAGCAACCACGGTCGGTATACGCCTTCAAACGCAGGTCGCCTCGGCTCTGCGTAAAGGCCTGGGCAAAAAGTTGCTGCTGATTGGCGATTCAATGTTTGGCAGCGGTTCATCTGGTGCAACAATTATCGCTGCTACGGGCCGAAGTGGAGAAGTCCGTTCTTACGGTGGGTCAACAAGCGATCAGGTCGTCGGCATGCTGAAGCAGGAGATTATTTCCTGGGGGGATCGGTGGGCTGGCCAGACGATGGCGGCATGGCATGGACAGAACAACCAACCCAAAACCGATGCCCGGGCCGCGCAGATCCGCGAAGGCTCAATGGAGATACACAGGCTTGCCGGCGCGTTGTTCATCCGCGTCCTGTTTCTGACAATCATGGGTCAGCGTGAGGCGACATGGAACGGAGTCAGGCTGGTTTACTCACAGCACGAAAATCAGTTTGCGCAGACCGGCTATCTCTATGAGCTCACAGAGTGGTATCGCCGTGTTTTCCCTGAACAACACGCAGTTGTATACGAAATCATGCTATCCGCAGCAACAGACGCTTTCGATCCAACATTCCCTGGCATGACAGAGAAACAGGTCGCCGCGAAATATGGCGTGCTTCCCTGGTCATTTTTTGCCAACGCTCAGATGCCAGCAGGACTGACAACAAACATGCTGAACTACCAGGGAACATGGAGCAACGCAGGAACGCCAACCGGTGGATCACACGCTGATTACTACCTGCGCATTGCAGCAGGAACTGTAGGTAATGTCATCGTGAACAATAACGGAACATGGTCAGAAATCGCCATCGATATTACCCATATGAGTCCGACTGGCGGCCAGGCGCTGGCATATGGTGGAAATGGTTTTAACCTGGGTAACAGCTATACCAACATCCCAGCCCGCGAGGGAATAGCGGACATTCTGAATAATAACTTTTTCTTTAAATGAGGTGACATATGGGACAAATGGTTAGTCTGAATGGCGCAAATTTCACAGATACTCGCCTGCCTATTTTATACAACTATCCTGGACTCTGCGCAGGATCGCTGATGCTGCTCGATGCTGAGAAAATAGCCGCAGATTTTAATTTTTCTGCCACAGCAGTTACGACGTATACAGATAATCTGGCTGCTGAAGTGGCGGAGGAACTGACGGCTAAAACGGCGAAGGATTTGCGGCTAGCATGGAATAACTCGCTGGTAACTACTGGTGAAGCACCAGAAGCCTTGTTTGAAAGGACGGATAAAGGGGGAATTCACGGTATCGTGTCGCTGCTCAATCAACAGGTAGGACACCGTGGGCGCTTCCAGTGCCCCGGCATCATGGAATATATCGCAGCACATCAGAATGAGCGCCAGTTTGCATTATTCATGCATTATCAGGTAACGAGGACAGGTGGAGGCACAGGCGCGCAACAGGCGGTCGAGTGCATTATTTCATCGCAGGTATCCCCCTCAGCAAATCGGCTGATTATCTCGCGGCTTCCTAACATGATTTCAGATGAGGCAGGCTTGCACAGTCAGCTCTCAGATAAGGCAGGGGCAGACCTGACCTCAACGGTTTATTATCAGGATTTACCCGTGTGGGGGGCTGCGTCCGGGTTCGGTTCGTTGGTAAATAACGCCTGTAAATCCTGGATTCTTTATCGGTGCCATCTGGTTGATGTAACGGCATCCGGGATGACCTTTACAGAACTCACTGCTGCGGAACAGCAACTGCTTAATGTCAATTTTGGTGCTGGCGGTAAATACTCCAGTGACACTATACCCACAAGTCCATCTGCGCTGCCGTAA

Protein sequences of DBSCAN-SWA_1

>NZ_CP046115|2375438:2389518|2383447_2383723_+|WP_154680228.1|DBSCAN-SWA
MGIEAIAGLVAILFGLIAGAFGIGHARGTNKAESKAKQQRTEEHAAASIAAAERKAEVTKEARDVEESVKRMGNVDVDRELREQFTRPGGG
>NZ_CP046115|2375438:2389518|2386026_2386428_+|WP_154680231.1|DBSCAN-SWA
MKIDHEYLKGLLEAFECSDKPETDIRHLHDLGFSYQTTEFLFHMRLLDDRNLIARTDGRSGFGFSESADDGGSWSVLPLRLTANGHDFLEAIRNKEVWATLKTSFKDASIGTLVTVSKELFNRILAKQLDKYI
>NZ_CP046115|2375438:2389518|2375438_2376248_-|WP_154680218.1|DBSCAN-SWA
MVETLLEVRNLSKTFRYRTGWFHRQTVEAVKPLSFTLRERQTLAIIGENGSGKSTLAKMLAGMVEPSTGELLIDDHRLEFGDYSFRSQKIRMIFQDPSTSLNPRQRISQILDFPLRLNTDLEPEARQKQIIETLRMVGLLPDHVSYYPHMLAPGQKQRLGLARALILRPKVIVCDEALASLDMSMRSQLINLMLELQEKQGISYIYVTQHLGMMKHISDQVLVMHHGEVVERGSTADVLASPLHELTKRLIAGHFGEALTADAWRKDGK
>NZ_CP046115|2375438:2389518|2382815_2383445_+|WP_154680227.1|DBSCAN-SWA
MNQSQFQRAAGISAGLAARWFPHIDTAMNEFRITSPLDRAMFIAQCGHESTSFTQLVESFNYSVAGLAGFVKAKRITQDQANTLGRKTYEKVVPLERQRAIANLVYSNRFGNQAAGDGWKFRGRGIIGITFLDNYMKCGNALKLDLVSNPELLEKDINAARSAAWFYTSKGCLKYLGDLGRVTQIINGGQNGIDDRRARFLKAKSVLVG
>NZ_CP046115|2375438:2389518|2379716_2379956_-|WP_049101131.1|DBSCAN-SWA
MRLINRSKQSPLGRQACETALAKHVELYGDYGRQKTKRTYTIEVNGSKITVEVVNRKCSYVATAMNCARRLQHLPGQSN
>NZ_CP046115|2375438:2389518|2382537_2382816_+|WP_154680226.1|holin|DBSCAN-SWA
MVNDHSALANSIICAVIVLALMFYQRGNARHRPGISVLAYLMVLVYASIPFRFLFGLYESSNWLVVMANILICGAVLWFRGNVARLIDALRN
>NZ_CP046115|2375438:2389518|2378308_2379496_+|WP_154680221.1|integrase|DBSCAN-SWA
MLTDTKLRKSLGKKRDKIEVISDAHGLNVRLSTSGSITFFYRYRWNGKAVQLTIGDYPTISLSQARERRQQFRAWLTEGLDPRRKTVLEKQKKTEALTVKEAFDYWEKYYCIPEGLVKIKVNRRDFNNHIAPVLGDMIVDQTTKAHWLSLFDDMGRRVVTGQMLGLMQRTFRFCSNRGVINVNPIESLRRSDVGLTAAVKDRWLSDEEIKTVWNTLPEMKYRQQLIMKFLILTGCRSTEIRTAKWEWFDFQEGTWTIPASDYKTGKSVRRALPEAVVNMMKTEKETSVSNHVVTLSRYKGPEDDRPPQQPNVALFSAQIIAKTGMKTWSLHDLRRTIATRLSELGAPPHVIEKLLGHHMSGVMARYNLHDYLDEQRHWLAVWQTHLEKLIGQPLV
>NZ_CP046115|2375438:2389518|2383864_2384137_+|WP_154680229.1|DBSCAN-SWA
MSEAKPQDGSTVKGYRTLTTGDIERMNRLKDVSRHFCNLLDTEHNSTMDGVVKEESERNEALRCLDIARTKMQEACMWACRAVARPDADC
>NZ_CP046115|2375438:2389518|2376249_2377242_-|WP_154680219.1|DBSCAN-SWA
MPLLDIRNLTIEFKTNEGWVKAVDRVSLTLAEGEIRGLVGESGSGKSLIAKAICGVTKDNWRVTADRMRFDDIDLLRLSVRERRKLVGHNVSMIFQEPQSCLDPSERIGQQLTQNIPGWTFKGRWWQRFGWRKRRAIELLHRVGIKDHKDAMRSFPYELTDGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIIRLLTRLNQNNNTTILLISHDMQMLSKWADKINVMYCGQTVESAPSEELVTIPHHPYTQALIRAIPDFGSAMQHKSRLNTLPGAIPLLEQLPIGCRLGPRCPYAQRECIETPRLVGARNHLYACHFPLNMEKE
>NZ_CP046115|2375438:2389518|2381217_2381511_+|WP_154680224.1|DBSCAN-SWA
MANDSRGNEVVFNRAYLNLCSENKKLSPLVIVKKIKEHNIVECFSFGLKGAIDIESKCLFLRYKYPWPDFEIELVRKKGGDYEFMLFHNDFLKGIDN
>NZ_CP046115|2375438:2389518|2380472_2380754_+|WP_154680222.1|DBSCAN-SWA
MANKSREQKQACVQAIIELTREKGRLTVKEACAELRMCRDTAGRYFQAAVRTGKVIRYGRLGLFRDLRATIDFDLQRFSHRKNPQHNEGMGEG
>NZ_CP046115|2375438:2389518|2379995_2380184_-|WP_154682696.1|DBSCAN-SWA
MVDAKNKVEAAINSLPNPGDPEAEVLFTKAESTLTSSRRHLGDELYDQFRITLDDMKPEYVG
>NZ_CP046115|2375438:2389518|2385274_2385460_+|WP_154682697.1|DBSCAN-SWA
MGVLIDSALKGYLFLLLDMWPVLLVAFVGLAFSFYGVLMPKTAITLLLLAVVIGIAGGIYA
>NZ_CP046115|2375438:2389518|2377241_2378132_-|WP_154680220.1|DBSCAN-SWA
MPYDSVYLEKRPPGALRTVWRKFYGDTTAMVGLYGCAALVLLCVFGGWFAPYGIDQQFLGYQLLPPSWSRYGEVSFFLGTDDLGRDVLSRLLSGAAPTVGGAFVVTLGASLLGLVLGVIAGATHGLRSAVMNHILDTLLSIPSLLLAIIVVAFAGPHLSHAMFAVWLALLPRMVRSVYSMVHDELEKEYVIAARLDGASTLNILWFAVLPNITSGLVTEITRALSMAILDIAALGFLDLGAQLPSPEWGAMLGDALELIYVAPWTVMLPGAAIMISVLLVNLLGDGIRRAIVAGVE
>NZ_CP046115|2375438:2389518|2388681_2389518_+|WP_154680233.1|DBSCAN-SWA
MGQMVSLNGANFTDTRLPILYNYPGLCAGSLMLLDAEKIAADFNFSATAVTTYTDNLAAEVAEELTAKTAKDLRLAWNNSLVTTGEAPEALFERTDKGGIHGIVSLLNQQVGHRGRFQCPGIMEYIAAHQNERQFALFMHYQVTRTGGGTGAQQAVECIISSQVSPSANRLIISRLPNMISDEAGLHSQLSDKAGADLTSTVYYQDLPVWGAASGFGSLVNNACKSWILYRCHLVDVTASGMTFTELTAAEQQLLNVNFGAGGKYSSDTIPTSPSALP
>NZ_CP046115|2375438:2389518|2387026_2388673_+|WP_154680232.1|DBSCAN-SWA
MEYRRSFGLKVAGKAQGAPYDPGAVPSTNRRGRLTSPTISTPSGSFSAGDYYSYEAYNVNSSVSETVPGNWNGQSVYLGDLLVYDGTSWRIQRSPGSGAARKNDTWYLVTSAGTFAGMTLSPGDALLFLTLQTAGGGFLQPQFAALNTTSDLLLYGGEFSPAAGYPASDRPNVVYQASASGNTGGESYTAGDYAIFDGISWVRIANDEAVTVPAGQSISLRCAANADEWEFRRADKEATTVGIRLQTQVASALRKGLGKKLLLIGDSMFGSGSSGATIIAATGRSGEVRSYGGSTSDQVVGMLKQEIISWGDRWAGQTMAAWHGQNNQPKTDARAAQIREGSMEIHRLAGALFIRVLFLTIMGQREATWNGVRLVYSQHENQFAQTGYLYELTEWYRRVFPEQHAVVYEIMLSAATDAFDPTFPGMTEKQVAAKYGVLPWSFFANAQMPAGLTTNMLNYQGTWSNAGTPTGGSHADYYLRIAAGTVGNVIVNNNGTWSEIAIDITHMSPTGGQALAYGGNGFNLGNSYTNIPAREGIADILNNNFFFK
>NZ_CP046115|2375438:2389518|2385567_2385951_+|WP_154680230.1|DBSCAN-SWA
MFTVKTIINGVTHICEQPSVTIARAGCERFDDILLQTNDHSNPDFAIWLPGVYSDPQCTDALQEEELIVSEREGVLDEDAIAILVEDFESPEHAKRKAFDGVRYQFIYPGDQVYVMNSHGSTIETVK
>NZ_CP046115|2375438:2389518|2380757_2380910_+|WP_154680223.1|DBSCAN-SWA
MTSKLIRERIELIANFHRAMTLPPSHAEIEELARMALAAMDDAYDLRLYC
>NZ_CP046115|2375438:2389518|2381930_2382164_+|WP_154680225.1|DBSCAN-SWA
MRIEVTIDKNKKLPEGALAALQEELMRRIDEKYCDFSLSLRRASMDGLSVLGGDKGDEERIEQILPETKETSDGWFY

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_154680218.1|2375438_2376248_-	peptide ABC transporter ATP-binding protein SapF	G3M9Y6	Bacillus_virus	6.1e-14	27.4
WP_154680219.1|2376249_2377242_-	peptide ABC transporter ATP-binding protein SapD	G9BWD6	Planktothrix_phage	2.7e-08	26.7
WP_154680220.1|2377241_2378132_-	peptide ABC transporter permease SapC	NA	NA	NA	NA
2378118:2378133	attL	NA	NA	NA	NA
WP_154680221.1|2378308_2379496_+|integrase	tyrosine-type recombinase/integrase	K7PGY1	Enterobacteria_phage	2.9e-121	52.7
WP_049101131.1|2379716_2379956_-	DUF4060 family protein	M9P0E0	Enterobacteria_phage	1.6e-23	68.8
WP_154682696.1|2379995_2380184_-	exodeoxyribonuclease VIII	H6WRX0	Salmonella_phage	2.9e-20	72.1
WP_154680222.1|2380472_2380754_+	DUF977 family protein	NA	NA	NA	NA
WP_154680223.1|2380757_2380910_+	hypothetical protein	NA	NA	NA	NA
WP_154680224.1|2381217_2381511_+	hypothetical protein	NA	NA	NA	NA
WP_154680225.1|2381930_2382164_+	DinI-like family protein	A0A0M4REN2	Salmonella_phage	1.2e-18	55.8
WP_154680226.1|2382537_2382816_+|holin	phage holin family protein	K7PKN9	Enterobacterial_phage	7.1e-31	68.5
WP_154680227.1|2382815_2383445_+	glycoside hydrolase family 19 protein	F1C591	Cronobacter_phage	7.6e-89	76.3
WP_154680228.1|2383447_2383723_+	hypothetical protein	G8C7W1	Escherichia_phage	1.1e-20	60.0
WP_154680229.1|2383864_2384137_+	hypothetical protein	G8C7W3	Escherichia_phage	6.3e-32	75.3
WP_154682697.1|2385274_2385460_+	hypothetical protein	NA	NA	NA	NA
WP_154680230.1|2385567_2385951_+	hypothetical protein	Q6UAR9	Klebsiella_phage	2.6e-63	93.7
WP_154680231.1|2386026_2386428_+	DUF2513 domain-containing protein	NA	NA	NA	NA
WP_154680232.1|2387026_2388673_+	hypothetical protein	A0A0S1S5D9	Klebsiella_phage	7.4e-184	57.6
WP_154680233.1|2388681_2389518_+	hypothetical protein	A0A0S1S106	Klebsiella_phage	2.1e-94	61.9
2400071:2400086	attR	NA	NA	NA	NA

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NZ_CP046115|2457315:2487419|DBSCAN-SWA
CTTATTTTACTTCGACTACGTTCAGGCGCAGTTCATCCAGCTGCGCGTCATCCTCTTCGGGCTGCCAGCCGGCTGGCTGCATCGGGATCTCTTCGCGATCGAAGGCCAGGTCGCCGCCGTCAACGACTTCAGAGCCGTGTTTAATACCTTTAAAGTCGAACAGGTTTACATCGCTAAGATGGGAAGGCACCACGTTTTGCATCGCGCTGAACATGGTTTCGATGCGTCCCGGATAGCGTTTGTCCCAGTCGCGCAGCATATCGGCAATCACCTGACGCTGAAGGTTTGGCTGCGAGCCGCACAGGTTGCACGGAATAATCGGGAAACCTTTCGCCTGAGAGAAACGTTCAATATCTTTTTCGCGGCAGTAAGCCAGCGGACGAATAACGATATGTTTACCATCGTCGCTCATCAGCTTCGGCGGCATACCTTTCATCTTTCCGCCGTAGAACATGTTCAGGAACAGGGTTTGTAAAATGTCGTCACGGTGGTGGCCAAGGGCGATTTTGGTCGCACCCAGCTCAGTGGCGGTGCGATAAAGAATGCCGCGACGCAGACGTGAGCAGAGCGAGCAGGTGGTTTTGCCTTCCGGGATTTTCTCTTTAACAATACCGTAGGTATTTTCTTCAACAATCTTATATTCAACGCCCAACTGCTCTAAATATTCCGGCAGAATATGCTCCGGAAAGCCCGGCTGTTTTTGATCGAGGTTGACCGCTACCAGCGAGAAAGAGATGGGGGCGCTTTTTTGCAGATTGCGCAAAATCTCCAGCATGGTATAGCTGTCTTTACCGCCGGAGAGGCAAACCATAATGCGGTCGCCATCTTCAATCATATTAAAATCGGCGATTGCTTCGCCGACGTTACGGCGCAGGCGCTTCTGCAATTTGTCGATATTGTATTTTTCTTTCTTGCTAATTTCTTGATTCTGCAGCATTTAATAATGGCTCAATTCATAGTGTGGCATCAGAAGAGCTCGCGTTCTGCCAGCAATCTCATGGCTTTCTGCTGGTGCGTAGCATGTGGCGTGTATGGTACGGATTAGCGAAGGGAATGTCAGCACATTTAAGGTTAAATAAGCCCGACGGGTTATAAAGATAAAAGCCCGCCGAACGGCGGGCTGAGCGGGGATTAGCGCACGACCAGCACCGAACATTCCGCATGGCGGACAACTGCGGCGGCGTTAGAGCCCAGCAGATAGGTGGTGATATCGGGACGGTGCGAAGAAATAATCACCAGATCGGCGGGGAGAGACTTCGCCATTGCGAGAATTTTGTCTTTCGGCGAGCCCTCTGAAACGTGAAGATGGATACGGTCTTCAGGAATAGTAAACTTGCTCACAATCTCTTTCAGCCGCGACTCCGATTCGGCTTTCAGGTCATCCATCGCCGGTAGCTCTGCGGTGTAGGCCATTCCCAGCGAAGCGTAATAGGGAAGGGAGGGAATGACGGTCAGGAAATGCACCTCGGCATCATCGATTCTGGCTTCAGATTCAACGTGCTTGATAACGCGTTCAGTTAATTCTGTATCGGAAATATCGATGGGCACAAGAATCATTCTGTTCATAAAACCTCCTGGTAAGTAACCACTTAAAGTGTAGGCCATCCAGGAGATGAATGTACATTGAACCCAGTCACATTTTCGCTATCAGGCGCGGCGGCGTTCGGTAAATTTACCTTTAATAACGCCATCGTAAAAACGGCCTTTCGAAACAACTTGTAGAAAATCGCGGAAAATACGCGCCGGAACGCCGATATATTGCAGCGTTTTGTTATCGCGAAAGCGAATTTCAAGAATGCCGGAGGATTCATCGTAGGCGACGGAGGTGATTCGGGATGATTTAACAGGATGATGGTGCATGGCTGGCGTCCTCTACGGCTACGGCTTTTCCTGTTAACAATATATCATTCATTGGATGATTGTTTTAGGCTAATAGATATATTGTTTTGTTTTGAATGTAGCGGTCATAGGCGAGAGCAAGTAAGCCCGCCGTCGCCAGCGGGCTGCAACATCAGAACTGATACACCAGGCCCAATGCTACGACATTATCTGTAGATATGCCGTTGTCTTTGTAGAAAGTATCATCGTCGTCCAGCAGGTTGATTTTGTAATCAACATAGGTGGACATATTGCGGTTGAAGTAATAAGTTGCTCCAATGTCGACATATTTAACCAGATCTTTATCGCCAGTATTTCCTGCCGGATTAGCCGCATTGCCCTGCATAACCAGATCCTTACCTTTAGACTGCAGATAAGAGATTGCCGGACGGAGGCCGAAGTCGAACTGGTACTGCGCCGTCACTTCAACGTTTTGTGTTTTATTGGCGATAGTATCGCTGTTATTGCCATATGGGGTCATATTGCGGGTTTCAGAATACATGGTCGCCAGGTAGATGCTGTTGGCATCATATTTTAAACCCGCAGTCCATGCGTCTGCTTTATCGCCTCCTGCCGTAGAAGCGTGGGTCTGCTCATTGGTTCGGTCAGAAGAGCTATAGGCCGCCGCAGCGCTTATGCCCATGCCCAGATCGTAAGAGGAGGAGATACCGAAGCCGTCACCGTTAGCGTTTTTAACGTTACGGCCATTGCTGTTCGCGGTGCCTTCCTGATACTCGTGGCTGGACTGATTTTCATTTTTACCCTGATACTGCAGGGCAAAATTCAGGCCGTTGACCAGGCCGAAGAAATCGCTGTTGCGGTAGGTGGCAACGCCGTTTGCGCGGCCGGTCATATAGTTATCCGCTTTGCTGTAGGTATCGCCGCCGAACTCTGGCAGCATATCGGTCCAGCCTTCAACGTCGTACAGTACGCCGTAGTTACGACCATAATCAAATGAACCATAGTTAGCGAATTTCAGGCCGGCAAACGCCAGACGGGTCCACGCCTGATCGCCTGAGCTTTCGGTATTGTTTGCCTGGACGTTATATTCCCACTGACCGTAACCGGTTATGCGATCGTTAATCTGGGTTTCTCCTTTGAAACCAAAGCGAACATAAGTCTGATCGCCATCAGAGTTATTATCATCAGAGAAATAATGCAGGCCATCTACTTTGCCATAGAGGTCCAGTTTATTGCCATCTTTATTATAAATCTCAGCGGAGTGAGCAGCGCCAGCAGCTAATAATGCTGGTATAACGAGGGCCAGTACTTTTCTTTTCATTTAGATAATCCTTTAGCGGTTTTTGTTTTAGCTTCCTCCGGGGAAGTGAACTCATGCTAAAGGAGCAAATTAATATATGGTAAATATCAATTGTTACGATATAAGTAAAATCTAAAATAAATAATTCGAAGGAAATGATGATAATTGCAATGAATGGGTTTGCGGGAAATATATAAAATAAAAATTATACATGCCGGTTTTAATGTCGTATTATCCGGCCGTTATATGCCTTTTATTGTCACCTGAAAATTAATGTTGCTGTTCGTTCCTGAGAATGGTTTTTATTGGACGGTAAAATGACAAGCCCGAATTAATATTCGGGCTTTTTTTATATTCCAGAAAAACGTCGACCGGTTAACTTTCGGCTGCTGGTTTTTCCGCCTTACCGGCCAGCTGTGCAAGGAAGTCATAGCGTTTTTGCAGATCCGCAGCCGCATCCTTCCACAGCTGTTCCGCTACCTCCGGCTGTTGCGCGTTCAGACGACGGAATCGCTGTTCGTTCAGTAGCGTTTCTGCCAGCGCATCCGATGGCGGACGCGAGTCCAGCGCCAGTGGGAGCTTACCTTCATCGGCACGACGTGGATCGAAACGGTACAGCGGCCAGAATCCAGTGGCGGTCAGCTGGCGCATCTGATCGTGGCTCAGGGCCAGATCGTAACCATGCTCCTCGCAGGGGCTGTAGGCGATAATCAGCGATGGCCCCGGATAAGCTTCCGCTTCCTGAATCGCTTTTACCGTCTGGTTGAGCTGCGCGCCCAGCGAGATCTGCGCAACATACACGTGGCCGTACATCATCATGCTGACCCCGAGGTCTTTACGCGCCTTACGCTTGCCGTGCTCGCCGAACTTAGTGACTGCCCCCAGCGGGGTGGCTTTCGATGCCTGGCCGCCGGTGTTGGAGTAGCACTGGGTATCGAGCACCAGAATATTGACGTTTTCGGTCAGGCTCAGGACGTGGTCAAGGCCGCCGAAGCCGATATCATAGGCCCAGCCATCGCCGCCTATCAGCCAGATCGATTTCTCGACCAGCGCGTCGGCGTCGGTCAACAGCTCCTTCGCACCTTCTTCATTTGCCAGCACATTGCGTAGCTCGGCCACCTGTTCGCGGCGCGCCTCAGGCGTTGCTTCCGCATGGAGAGCGGCGTTGAGCTCGGCCGGAAGCTTATCGGCAAACTGCGACAGCAGACGCATAACGCGTTGCCGGTGCTGGTCGACGGTGAGACGGAAGCCGAGGCCAAATTCGGCGTTATCCTCGAACAGCGAGTTGGCCCATGCCGGACCGCGACCATTGGCATCGGTAGTGTACGGTGTGGAAGGGAGGTTGCCGCCATAGATTGATGAACAGCCGGTTGCGTTAGCGATCAGCATGCGGTCGCCGTAGAGCTGAGTCAGCAGCTTGATATAGGGCGTCTCGCCGCAGCCGGAACAGGCGCCGGAGTATTCGAACAGCGGGCTTATCAGCTGCGAGGTACGGATATCGATACGTTCCAGCTTGCTGCGATCTATTTCCGGTAGCTTGAGGAAGTAGTCATAATTCACCTTCTCTTCTTCAACATGTTCAAGGCGCGACATCATATTAATGGCCTTGATTTCCGGGTTCTGCCGGTCTTTTGCCGGGCAAACCTCGACGCAAAGATTACAGCCGGTGCAATCTTCCGGCGCAACCTGCAGAACGTATTTCTGGCCGCGCATATCGCGGGATTTGACGTCCAGAGAGTGCAGGCTGGCCGGCGCGTTTTCCATGGCTTCCGGGGAGACCACTTTAGCGCGGATTGCCGAGTGCGGGCAGGCGGCAACGCAGTGGTTACATTGGGTGCAAAGCTCTTCCTTCCAGATTGGGATCTCTTCGGCGATGTTACGTTTTTCCCAACGGGTGGTGCCCATTGGCCAGGTGCCGTCAGGCGGCAGAGCGGAAACCGGAAGCGCATCGCCGAGTCCGGCCAGCATTGCGGCGGTTACGGTTTTGACGAAATCCGGCGCGGCGTCGGAGACGACCGGCGGACGGTTCGGGCTGCTGGCGTCCACCTGCCGCAGCGGTACTTCGGCCAGCGACTCGCGCGCGAGGGCCAGCGCCTGCCAGTTACGCTCCACCAGCTCCTGGCCTTTGCTACTGTAGCTTTTGGCAATCGCGCCCTGTAGTTCCGCCAGCGCGCTATCGCCCGGCAGGATCTGCGTCAGATGGAAAAATGCCATCTGCATAACGGTATTAATACGCGCGCCGAGGCTGCATTCGCGGGCAATTTTTGCCGCGTTGACGATAAAGAAACGTGCTTTTTTCTTATTCAGGGTAGCCTGGACTTCCTGCGGCAGACGCGACCAGACTTCGTCGGCGCTGTACGGTGTGTTAAGCAGGAATATGCCGCCAGGCTTCAGCCTCTCAACCATCTGATATTTATCGATAAACTGCAGCTGATGACAGCCGACGAAATCCGCCTGCGAAATCAGATAAGAAGAACGAATCGGCTTCTCGCTAACGCGCAGATGGGAAACGGTCAGGCCGCCGGCTTTTTTCGAGTCATAGACAAAATAGCCCTGTGAGAACCACGGCGTTGAGTTACCAATAATTTTGATATTGTTTTTGGTGGCTGAGACGCTACCGTCACTGCCGAGCCCGTAGAAAAGGGCTTCCAGCTTTGCTTCCGACGGCAGGGAATTTTCTGGCAGCGGCAGGGACAGGTTGGTAACGTCGTCGTAAATGCCAACGGTAAAGCGCGGTTTTGGTTTGGCGGCGTTCAGTTCGTTGAAGATAGCCAGGACGCACTCCGGACCGAACTCTTTTGACGAGAGACCGTAGCGACCGCCGATGGTACGCGGCAGGGTTTCTCGTTCGCCGCGGTTGAAGGCTTCCGCCAGCGCGGTCATCACATCAAGATATAACGGTTCTGCCTGAGCGCCGGGTTCCTTGGTGCGATCCAGCACCGCCACCGCCCGGGCGCTTTGCGGCAGAACGTCCAGCAAATGCGCAGCAGAGAAGGGGCGGTAAAGACGAACTTTCAGTACGCCGACTTTTTCACCGCGGCCCAGTAATTCATCCACCACTTCCTCACAGGTACCAATAGCGGAGCCCATAATCACGATAACGCGTTCGGCCTGAGGATGCCCGTAGAACTCAAAGGGTTTGTATTTACGTCCGGTAGCGGCAGCGAAATCGTCCATCGCTGTTTCAACATGCTCGTAGACCGCGTCATACCATGGATTCGTTGCTTCACGTGACTGGAAATAAGTATCCGGGTTAGCTGAAGTACCGCGGATCACCGGATGCTCCGGGTTAAGGGCTCGCTGGCGGTGTTCGTCGATTTTATCCTGCGGTAGCAGGCTGCGAATAGTATCGTCGGCCAGCGGAGCGATTTTGTTGATTTCGTGAGAAGTGCGGAAACCATCAAAGAAATGAATAAACGGTACCCGGCTTTGCAGGGTGGCAATGTGCGAAATCAGAGCAAAGTCCTGCGCCTCCTGAACGCTACTGGCGCAAAGCATCGCGCAGCCGGTCTGGCGTACGGCCATCACGTCAGAGTGATCGCCAAAGATAGAGAGCGCGTGGGTGGCTACGGTACGGGCGGCGACGTGCAGAACAAACGGCATCAGCTGGCCTGCCAGTTTGTACAGCGTCGGGATCATCAGCAGCAAACCCTGCGATGAAGTAAAGGAGGTCGAGAGGGCGCCGGTTTGCAGCGCGCCGTGTACGGCACCGATTGCCCCTGCTTCCGACTGCATTTCGACCACGCGCGGAACATCGCCCCAGACGTTTTTCAGTCCGTTACCAGCCCAGGCGTCCGCCTGTTCAGCCATGGTGGAGCTGGGGGTAATCGGGTAGATGGCGATAACTTCACTGGTGCGAAACGCGACAGAAGCGACCGCGCCATTACCGTCAATAGTGATCATATAAATACTCACATTGCTAAATTTTTGATAAATGATGTTTTAATGCTCAGTAATGCAACCTGAACACTCGCTCATGTGTGCCCGGGAACCCGCATTAGCGTAAGTACTCCGGTATCTTATAAATTCATTTTTCTCCTGCCATTCACGGGTGATGCGTTACCCGTCTGCTGGCGGCAGGACTACCTTGTTGGTGACTGACCGCTTAAGTATAGACGCCAGAGAAAGATGGTTTTTTGATCTCCGGTGGCTACAAAATCCATAATTTAAATAAATTAATTCAACTTATTACTCGGGCGTTCACGTATGAACGTTACCCTACACCAAAATCGGGGGCGCCATTTTTCCATAAGTAGCAATGTTGTCGGTCGTTCCGCGCCACACGATCCGTTGCAGGATTTTTTTATAACCTATAGGTAATTTAATGGAGTTTTGCTATATTTTGGATACCTGATGGTAAATGGCGTAACAATAATGGCTATGGACAAATACGAAATCAGAAGGCAGCGCTTGCTCTGGATCCGTGATAATTTATGCGGTGGTAAAGCTATTGATGTAGCCCGTACAATTGGCCGGGAGCCTTCCTATGTTTCAAGGATGCTCTACCCCGAAGGCAAGAAGCAAAAGAAAAGGATAGCTGACGAAATGGTCGAACTTATTGAGTCTTCGTTCAATCTGCCCCGCGGATGGATGGACGGTATCACCGGGAATGTTGATGTTGAAAAAGAGCCGGTGGAGGATTCTCCTCAGATGAACTATGTGATTGAGGTTCTGGATGCGCAGGCCAGCGCGGGACCGGGTTGCATAGTCTCAAGTGAGGTTGATGAGACGGTCAGCAGTATTACCTATGACTCCGTAGGCGCGCTGAGACTTTTTGGTAATAGACCCGCTGAACATATCAAAGTGATCACCGTATCCGGCGATAGCATGTCTGGAACCATTGAGACCGGGGATTACATTTTTATTGATGTTTCAAAAGATTACTTTGAAGGTGACGGTATTTATGTCTTTTCTTTTAAAGGTGCCGTTCTGGTGAAGCGTCTTCAGTTTACGGCGGATGGTCTGTTGGTTCACTCCGATAACAGCAAGTATGCGGACTGGACGATTGGCGAAAGCCATGAACAATATCTGAAGATTATTGGGCGCGTTATTTATAGCCATAGCGTCAAACGTTTCGTTTAAATACGCCGCATAATCCCGGACACGCCATCTGCTTTCAGGTATCGGTGCTTATTTAGCTGATTAAATTCCCGCAGGTATGCTGCCCGTATGTAGGGGCATATCGGCGGGATCGTTCGATCATCCTGACATTCTCAGTTCTCAGTTCTCAGTTCTCAGTTCTCAGTTCTCAGTTCTCAGTTCCCAGTTCCCAGTTCCCAGTTCCCAACCATCCTTGTCTCCTTCGTTTTAACCACTTTCCAGCGTATTGAAAAAATACCATTTCATTTCAATGAGTTGCATTTATTATCTTAAAAATATACCTACAGGTATTTATTTTTAGATTACCTTTGGGTATCATTTGTTTCGTCAGCTTGATGCGTACCACCATCTTGATGATGAATACAACGATTCAGGGATGAATCTACGTGGCTGAAAAGCCAGCGCCACCAGGCAATGCGCTTTGGGGTGAGGCCATTGGGCAGCAGGAGAGTTACCTGCGATTCCGATGAACCACCGCCAAAGCTCACTAAGGAGGTCGCCATGTCCCGTAAAACGCCGTTTAATGGTTCCGCGGCGGGTAGACGCCGCGCACAGCGCTCGCACTTACAAAATTCGGCAGCCCTCAGTTCAGATTTCATTCACCGGCCAACACCTTGTCGCGCTCAGATACAGGCGAAGGGGAAACATTATACGCCTGAGCGTATTGAGGATGCGCTGCCGATTAAATTTATTGCTCAGGATGTTTTTTGGCACCGGGAAGAATATAAACGTCAGATTTTGCGCGCAACTCTCATTTACCAACAAGAGTTTGCTCATCGTTATATTGAGCCAGGAACATATCTGTGCCACAGAGCAATTTATGCGCTTGGTCTGCAAAAAAGAAAGAAAATTACGGCGAGGTAAAAGTGGTGGTGATATCAGGCATTACGCTGCGTTTCGTGATTAATCACCAAAAAATAAAATGAAAGAAAGGAGGGTAAATGTCCGATCCTGTTTCCGGTACGTCGGCATTTGTTGCTGGTGGATTAATGGGAGCTGGTATGTTTGGGTTGGTAACAGGTATTGATTATGGCGTGGTGTTTGGGGCTTTTGCTGGCGCTGTATTTTATGTGGCGACGGCAGTCAATATCCCGCGTTTTAGACTGGCTGCCTATTTCATTACTTCTTTTATTGTCGGCGTTCTTGGGGCCGGGTTAATTGGTACTAAACTGGCATCCTGGACAGGGTATAATGAAAGGCCTTTAGACGCTTTAGGCGCTGTACTGCTCTCAGCACTAATTATTAAGATACTGACCTTTCTGAATAATCAAGAGCTGACCGACCTGTATAAAATATTAACCCGCAATAATAATGGGCGTTCGAATGGAAAGTAACCTTCCTGCGCTAATTAATTCAGTTCTCTGTTTTTTTATTACCGTGAATTTGATGTTTTATCGACGAGTCCAGGACAGAACATATCGTCCATGGATATCATACACAGCTTATTTACTGGTAATAACCTATGCCAGCATACCTTTTCGCTATCTCTTCGGCTTGTATGAATCGACGCATTGGCTGGTGGTCATAGTTAATTTTTTTGTCTTTATTGCGGTATTCCTGGTTAAGGGAAATATTGCACATTTAATCGATAAATGAGGTATGTATGAGTAAAGATGATATTTTTAATGCCATATTGGATAAGGAGGGCGGTTATGTAAATCATCCTGATGATAGAGGCGGCCCGACGAATTGGGGAGTTACTCAGGCGACCGCCCGGGCTCATGGTTATGATGGTGATATGCGAAAACTGACGCGCCAGCAGGCGCTGGATATTCTTCACGCTGACTACTGGATTGCGCCCCGGTTCGATCAGGTGGCTGAGATATCTACCGCAATCGCTGACAAACTGTGTGATGCCGGTGTCAATATGGGACCTTCTCAACCAGGCAAATGGCTTCAACGCTGGCTAAATGCTTTTAATAATCGCGGAGTACTTTATCCCGATCTCATTATTGATGGTGTTATTGGTCCCCGAAGCTTAAATGCCCTGAATCATTATCTTATTCGCAGGGGGAGTGAAGGCGAGCTTGTCCTGTTGCGAGGATTAAACTGTAGCCAGGGCCAGTATTATCTGGAGTTAGCTGAAAGAAGAGCTGCCAATGAATCATTTATATATGGTTGGTTGAGAATGCGAGTATCTATGTAATTTACTGTATTACTAATTTAATAAGTTCATAATCGAAATCTGGAGACATAGAATATGTATACATCAAATGATTTAACCCTCTCAATGTTTTACTCATCGGCCATTGCTGAGGAAACCGGCAATAAAATTGCAACGCTCACCGTGCAAACCATGGGGCCATCGGCGGAAATTCTACAAATCAGTAAGCTGCATTGTATTACTGATGAAACCAGAACGAAAAACTATAGTATTGGTGAACAATTTATTGCTAATGGCTCCGATCCTCTTCTTGCAGCTATCGAAACCTGGTGGCGTGATAATTCTGCTATTTTAATTCAGGAGCTCATGGTGGAAGTTATGGATTTCATTTCCGGTAACATCAACCAAAACGCAACCTGGATTGGCCAGTATGGAATGAAGATTTTTGAAAATGAGCCGGTGACAAAACGTATGCCTGATAGCGTATTACAGAACGGTAGCTCCACGGACGCCTGAAAAATTACCAGGGAAATGACTTTGGTTTTAAAGCGTAATCACGATAACGCATAACAATAAGTCATAATTAAACAAGCTTTTCTTTTTATAAATTACATTCAAATATTTAAATATCAATAATGGAGATATTATTATGGCTTTTGCTCTGCCTAATGGCTCAACCGTTTTTGTTGGCTCCGGCCTGAGTAATCCGGTTTCGGTAAGTGCGGTTTCCAATGCTGAAGGCGCCGTTTTTAGCGTTGCGGAAAATCATAACCTTAAGGTTGATGATGTTGTACTTATTTCTTCGGGCTGGGGAATCATCGATGGTTTAGTTGCCAGAATCACTGCGCAAACAACCAATAGCGTGACCATTTCGGTTATTAACTCCAGCGATCGCAATTTTTTCCCTGCTCATGCTGGCGGCGGAAAGTTACAGAAAATCACTGAATGGACTGAAATTCCACAGATTACCGAAGTCGCGCAGTCAGGTGGTGAACAGCAGTATGCACAGGTACAGTTTCTGGCAGACGATCGCCAGCGTAATATTGGCACCTTCAAGGCGGCAAAAAATCAAACCTTCACGTTAGCCCATGATGCTTCTTTACCGATCTACAACGTGTTGAGCATGGCGGATCGCTATGGCCAGGTTTTACCGCTACGCATGTTTGTTCCTAATGCGAAAGAGTATCGCTATTGGTCCGGTGTTCCGTCATTCGATCCGCAGCCGGTGACGGCCGTGAATAGTGTTGAAACTGTACAAGTCGCGTTTTCCATTCACTCGCGGGATATTACCTTCTATAAATCAGAAGATTAATATTTTCCTTATCTGCAGAACATAAATTAAATTCGATCGGGCTCCTGCGGGGGCCTTTTTTAAAGGGTATTTATGAGCGCCATTTTCAAATTACAACCTAAACCGGTTTTTAAAGCTGATGTTGTTATTCCCCGTGCTGGTGAAGAAGACGGAGTACTGAATTTTACATTTAAGCATCGGCCAATAAAGGAACTGGCAGAACTTGAAAGTATTGACGAGAAAACGGTCAGTGATTTTTTACTGGAGATCGTCGACGACTGGGCATTATCTGAACCCTGTACGCGAGAAAATATTGGGGTACTGGTAGATAACTATCCAGGGGCGGTTAAAGCAATCATGACCACTTATTATCAGGAACTGACGGGGAATCGTGAAAAAAACTGATTGCGGTTGCCTCGGCATTCTATACGCCTGAACCATCAGCGGATGAGCTGAGCGCATTCGGTCTGACAGCCGAAGACTATGATGACGTTATTATCAACGTCTGGCCTGATATCTGGCCCGCGTTTGTCGTCTTTCGTGCGGCCAGCACGCAGTGGCGCACCAGCCCGGGTGGGGTCATCGGTCTGGATTACAATGTCCTCGCATGGCTCATGAAGGTTTACGATGTAGCTGACGAGGTAACCGCAATAAACGATCTTCAGGTAATGGAACGGGTGGCATTAAATATCCTGAATAAACTTCACAACTAGTCAGGACTTTCAGCGGGAGTATGTTCTATTTATTAATCAAACTAAGCCAGGCTACAGCCTGGTTTATTCTTTCAGGAGAGAGTCAATGGCGAGTGATACAACAATGACGCTGCGCATGAATAACAGTGAGCTGGAAAAAAACATCCAGCTTCTGGATAAATATCAACAGAAAGTAACTGTCGCCAACCGTAAAAGTGAAGAGTTTAATAAGACTTTTCGTGGCGCAACCGATATACAGAAAAAGCATACGGATAGCCTGAAGAGGTTAATGCAGACGCTACCGCTCCCTCCAGCCAGAATGGGATCAATACTTCAGGAGATGATCAAGAAGTCTGAGGAGGAGACCTACAATATAACATCAGGTCCTAAAAGTTACTGGGATTCATTAACAGGAATGGATAGCACGTCAAACTTTGAGCTCGGTAATACGGCAAAAGTTTTCCAGTCAGGCGTAGAGCCAGAAGCGAGTCCCGGCGATCATAATCAGAAAGGGAGTAAGAGCGACTGGCTCGGAGGTTTAATAGCAGGGGCCAAAGAGGCATGGGACAAATTCCTCGAGGACGGGAAAAATGTTCACGGCAAGCTTAAAGAATTAGCCAAAGATGCTTTTAGCTCAATGGGAAACTCGCTGGTGGAATATATCACTACAGGAAAGGCGAACTTTAATGATTTCCTGATGACCTTCCTGAAAGGGACGCTGAAAATGCTGAGCCAACTAATGCTGGTAAAAGCCATGGAGGCTTCCTTCAACGCGATGTCGAATTCCGGTATTGGTTGGATTTCATCCATCGGTAAAATTTTTATGGGTCACTCTGCGGGTGGATATACCGGAGACGGCGGTAAATATGAGCCAAAAGGGATTGTCCACGGCGGGGAATTTGTTTTTACCAAAGAAGCCACCGCGGCAATTGGTATTGGCAACCTTTATGCCATGATGCGCGGCGCTCAGGGGTATGCAGGGGGAGGCTACGTAGGAACGGCATTAATGCAGGGACTGGGGTCTTCAGGCTCAGGACCACTCACCGTTCAGACTTCCGTACTTATTCAAAACCAGAGCACAGAACCGCAGGCGACGGACAATAACGGCGCGCTAAATCGCGCATGGCAGCAGACGATAGACCGCTCAGTTCGCGCGGGTGTGGCGAATGAATTGAGGCCTGGCGGCCTTATCTGGAATGCGAACCACGGACGTTAACTTTTTAATCCCGGAGAAGATATGGCAATAGAAACGTTTTCCTGGCCAACGCAAATACAAGCGGGTCTGCAGGGAGATTTTAATTTCACCGTGCGCGAAGCTCGTTTCGCCGACGGATATCAGCAGGTCGTGGGCGATGGCCTGAATTTTGAAAAACAAAGCTGGCCGGTGACATTGACCGGAGAAAAAGAAGAGATATTAGCGATACTCGAGTTTATGCGCCGCCATGTCACGAAGTCGTTTATCTGGAATTCACCAACGGGTGAATCGGGACTTTATCGTGTCAGCCCCGACTCATTAAAGCTTTCGCCATTATCCAGTCAGGTAATGACGGTAACCGCCACATTTAACCAGGCATATGCACCATGATTACAGCTGATTATCAAAAACTTGAACCAGGGAATGAAATACGTTTACTGGAGATTGATGGCAGCGTCTTTGGAATGGATGATATCTTATATTTCCACGGACACAGCCTCGCCCATAGCGAGGCTGAAATTCTGGCTGCGGGAGGAGATGAAACTCGTTTGCCTGCAAAATCAATCTGGTGGCAGGGCAATGAATATATGCCGTGGCCGTGCATTATTGATGGTATCGAGTCTACTACCGCCGGTCGGGACGCTCAGCCATCTCTTAAGGTGGCAAATATTGACGCTTCGATTACCGCCCTGTGCCTGTATTACGATGATCTGGTTCAGGCGAAGGTGACAGTCCACGATACCCTGGCGAAATATCTCGATGCACGTAATTTCCCTGAAGGTAATGCAACGGCCGATCCCACGCAGGAAAAAAGAAAGGTCTATTTTATCGATGCTAAAAGTGAGGAAACGAATGAAGTTATTGAGTTCACTCTTGCCAGCCCGATGGATTTACAAGGAATAATGATCCCAACCCGCCAGCTGCATTCCATCTGTACCTGGTGCATCAGAAACAAATACCGCAGCGGCGATGGGTGTGATTATAACGGCCAGCGATATTTTGATAAAAATAATGTCCCTGTTACCGACCCGGCGCAGGATGTTTGTAACGGCACCTTGTCAGCCTGTAAATTACGCTTTGGCGAAGATAACGAACTGCCTTTTGGTGGCTTCCCCGGTACCTCTTTAATTCGGAGCTAATATGCGTCTGAAGGTTATCAGGGCTATTCAGGAGCATGCGCGAAAGGAATATCCTCGTGAGTGCTGCGGTGTGATTGCGCAAAGGGGACGGATAGCGCGCTATTTTCCCTGTCGCAATATTGCGGATGATCCCCTGGAGCATTTTGTCCTTGCGCCGGAGGATTATACTCAGGTAGAGGACTGGGGGATTGTTACTGGCATTGTCCACAGCCATCCTGATGCCACGACTCAGCCAAGTGAGTTGGATAAAGCCCAATGTGACGCGATGTTATTGCCGTGGCATATTTTCAGCTGGCCAGAAGGCGATCTGCGTACGATTTATCCGCGCGGGGAATTACCGCTGCTGGAACGCCCGTTTGTGCTTGGGCACTATGATTGCTGGGGATTGGTAATGAGTTATTTTCGCCAACAGCATGGCGTTGAGCTGAGGGATTATCGGGTGGACTATCCGTGGTGGGAAGATAGCTACCCTGATAACTTTTATCATGATTGTTGGTATGAATGTGGCTTTCGCGAGTTTTATGGTCCGCCGCAGCCTGGTGATATGGTAATTATGCAGGTACAGGCGAATAAGTGGAATCATGCCGGTATTCTGCTGGAGGGAAATATGCTCCTTCATCATCTGTACGGCCATTTAAGCCAGCGGGTGCCTTATGGTGGATACTGGCAGGAAAGAACGGTAAAGGTTTTGCGCTATCCTGTTAAGGATAATTAAGTGAGTAATAAAAAAAGCTGAAAGGCCTTCGAACTTCAAATTACATGATATCAAATGCATCCGCGCATTAGCGTTATTCAATTTAAGGAGCTTGACTCGCTTTCCAGTCAGCCAGGCGCGCAATATTATCGATGGTAGAATAAAAATTATGATTTTTCATAATATCTGCCGACAGATGGAGGATTTATGCAAGAACATATGGTCAGGATTGAATTGGGTGGAATTCTCGGTAAGAAATTTGGTAAACATCATTGTCGGATGGTAGCCACCGCATCTGAAGCGATAAGAGCATTGTGTTGTACCATAAACGGTTTCGAAAAGTTTATGAACAACAGTAAAGCTATGGGGTTAACGTATGCTGTTTTTAAAGGCAAGAAAAATATTAGTGAAGATGATATTCCGTTCCCCATTAGTGACAAAGTAATACGAATTGTGCCGGTCGTTATTGGTAGTAAAAAGGCCGGAATGTTACAAACGATATTAGGTGTGGCATTGATTGCGGTCGCCTCAATAGCAACAATGGGGGCCGGCGGTATATTTGCCGCCATTTCTGCTGGCAGCGGATGGGGAACCGCTGCCATGCTCGGGGCCTCAATGGCTCTCGGCGGCGTCCTGCAGATGCTCTCCCCTCAGGTTCCTGGTTTAGCCAGCCAACAATCTCCTGAAAATAAAGCCTCCTACGCTTTTGGCGGGGTGACAAATACCACTGCCCAAGGGTATCCGGTACCGCTTCTGTACGGTAAGCGGCTTATCGGTGGCGCAATTATATCAGCAGGAATTTATGTAGAAGACCAGCAGTAAAACATCCGCTTTCTCTCATTTATGGCCACCTTCGGGTGGTTTTTTTATGGAAAAAATATCTATGACACAGCACCTCATTAAAGGTTGTAAGGGCGGTAGTTCAAGCCCGCGTACCCCCACAGAACAGCCAGACGATTTACAATCTGTTGCGAAAGCTAAAGTTCTGCTTGCTCTCGGTGAAGGTGAGTTTGCCGGTGCGCTCACCGCGAAAGATATTTATCTTGATGGTACGCCGCTGGAAAATTCCGACGGTTCGCAAAATTTTAGCGGCGTTGCCTGGGAGTTTCGTCCCGGCACTCAGGCCCAGAATTATATTCAAGGGATCCCCGGCTCAGAAAATGAAATTAATGTGGGCATGGAAGTCTCCAGTAAAACGGCATGGAGCCGCTCATTTAGCAATACTCAGCTTTCCGCTGTTCGTCTGCGCTTAAAATGGCCATCTTTACTTAAACAGGAAGATAATGGCGATCTGGTGGGGAACACCGTGAGCTACGCCGTTGACCTGCAAACCGACGGCGGTAGCTGGCAGACGGTGCTGGAGAGCGCGGTTAGCGGCAAGACCACTGCCGGCTATGAACGGTGTCACCGCATTGATTTACCTCGCTCGACGACCGGTTGGGTGTTGCGATTACGCAAGGTTACCCAGGATGCAAACTCCTCGAAAACCGGCGATGTTATGATGCTGCAAAGCTATGCCGAGGTGCTTGATGCAAAACTGCGTTATCCCAATACGGCTCTGCTGTACGTAGAATTCGACTCGCGCCTGTTTAATGGCTCTATCCCTAAAATTTCCTGCAGTCCTCGCGGCCGCGTCATTCGCGTGCCTGACAATTACGATCCGGAGACCCGGGAGTATTCCGGTATCTGGACGGGGGCATTTAAATGGGCATGGACGGATAACCCGGCATGGATTTTTTACGATCTGATCGTCAGCGATCGTTTTGGCCTGGGGAATCGGCTTACCTCAGAAAATATTGATAAATGGACCTTGTATCAGGTTGCGCGGTATTGCGATGAGCCCGTACCCGATGGCAAAGGCGGAGATGGGACAGAGCCGCGCTATTTATGTAACGTCTATGTTCAGAATCGCAATGATGCCTATACGGTGCTGCGCGATTTTGCGGCTATTTTCCGCGGCATGACCTGCTGGAGCGGCGACCAGGTGATTGCTCTGGCGGATATGCCTCGCGATATTGATTACACCTACACCAGAGCTAACGTTATTAATGGTCGTTTTCAATACGCCAGCAGCAGTAGCAAAACGCGCTACACCAATGCGCTGGTTTCCTGGTCCGATCCGGAGAACGAGTATGCCGATGCGATGGAGCCGGTTTTTGAGCAGCCGCTGGTAGCCCGCTACGGGTTTAATCAACTTGAGCTGACGGCGATTGGCTGTACCCGCCAGTCGGAGGCCAACCGTAAAGGCCGTTGGGGGATCCTGACTAACAATAAAGATCGCGTGGTCACTTTTTCCGTCGGACTGGACGGTAATATCCCGCAGCCTGGCTATGTTATTGCGGTGGCAGACGAGATGCTGGCGGGGAAAGTCAACGGTGGCCGCACCAGTGAAGTGGACGGCTGCGTGATTACGCTCGATCGCCAGACGGAAGCGAAAGCCGGAGACAGGCTGCTGCTGAACCTGCCATCGGGCGTGACGCAGAGCCGAACCATCGAGGACGTTAATGGCCATGTTGTCACCGTCACCGCCGAATACGCTGAATTACCGGAAACGGAATGCGTATGGGCAATAGAATCTGACTCTCTCAGGGTTCAGCAATATCGTGTGGTGAGCGTTAAAGATAATAACGATAGTACATTTACTATTTCCGCTGCCGCGCACGATCCGGATAAATACGCCCGGATTGATACCGGCGCGATTATTGACAGCCGACCGATAAGCGTGATCCCTCCGGGGAATCAAAATGCGCCAGCTAATATCGTTGTTGAGTCTTATTCGGTCGTTAATCAGGGAATTAGCGTTGAAACGCTTCAGGTTCACTGGGCTCCTGTCAAAAATGCCATTGCTTATGAGGCACAGTGGCGTCGCAATGAAGGTAACTGGGTAAACGTTCCTCGTAGTTCCGTGACCTCGTTTGATGTCGGCGGAATTTATGCCGGGCGATACACGGTAAGAGTACGCGCTATCAATGCTGCGGAAGTGTCCAGCGGTTGGGCATATTCGGATGAGAAAATACTGACTGGAAAAATCGGCATGCCTGTTGCGCCGATTGCCCTGACTACTACGTCATTGCTGCATGGCGTTGAACTGCAATGGGCGTTTCCCGACGGCGCTGGCGATACTCAGAAAACGGAACTTCAGTACAGTCCCAATCCGAACGGCAGCGGGGCGATGGCTTTATCGGACGTAACGTATCCGGGGAAAACGTATCAGCAGATGGGCCTGCAGATTGCGGCGACGTTCTGGTACCGGGCGCGAATCGTCGATCGCCTCGGTAACGAAAGTCCCTGGACCTCCTGGGTGCAGGGGATGGCCAGCGACGATATCGACGAGTATTACGATAAGCTGACGGACGCGATTAAAGACACTGAAGCCTGGCAGGAAGCCCAGCGGGATATAGGGGACACGCATAAAGCGCTGACGGAAACCGCCGATGCTATTCGTGATGAGGTAGCCCAGCAGGTCACGGATATTCATCAGAATATTGATGATACCGTGGGAGGGCTCCGTAAACAGGTTGATGGGCAGATAGAGTCGGTTAATAAATCGATTACGGAGAATATCGACCTCGTCAACCAGACGTTGAACGACAATATTTCGGCAGTGAATCAGAGTCTCTCGGATGCCGTTACTGAGATGAATACTTCTGTTGACCAGCAGATTGCTGACGTTAACAAAGTCCTGGCCGAGGGTGACTCCGCGTTAAAATCCCAGCTGCAGACGGTTGAAAACAGCCTCAAACAGTCTATTGCCCAGGCCAACACCGGCTGGGATAAAGCGGTGAAGCAGGAGACCGCTGACCGAATCGCGGACGTGAACGCGAAAGCCGCGCAGGCGGCAGACCAGTTGCTGAATGAAAAAAATGAGCGCGTGGCGGCTATTGATAACCTGCAGACGGTTATCCAGGATGGCGATGAGTCGCTGGCCCGTCAGATTGCTGAAATCTCTGCCGGCAGCGGCCAGCAGTTTGATTCGTTCAGTATCTGGTACTTCGATAAAGACAACGAAGGGTGGACCGAGGATGACGCCGGTCAGGTACCGATGCAAATCACGGATGAGGGCTGGCTGAAAGCATCTAATAGTACGGCCTCCTGTCGCTCGCCCAATGGACAAACAATCCCAGCCTCCTCTTATCGCACTATCATGCTGCGTATCAAACGTGTCGGTAATCCGGTCTGGAAAGGACGGTTTTACTGGATTGGGGCCGATGAACAGGGCTGGAACGATGCTCGTTCGGTCACTATTGCAGAGCAGGAGTTTGATGGTGATGGTATCAGCGTGGTGGCTATCCCTGATGTGAACTGGAATGCGTCCGGCACCGTCCGTCGTTTTCGTATAGACCTGGCTCAGGGGCAGAACGCCGACAACTATTTCCTGATCCACTGGATCTCCGTTGGTCGCCCGGCACCGGCGGCCAGCACAGCCGCCCTGCGTAATGAGGAGATGGCGCGGACTCAGGCGGACGAAGCGGAGGCGATGAAGCGCTCCACGCTGGCGGCACAGATCCGGGGCACCACCGACAGCAATAGCCTGAGCGATTTACGCTCCGGTCTTCTCTACCAGGAAATGAATGCCCGTATCACCGCTGACCGTGCAGAAGTCGTGGCGCGGGAGTCGCTGCAGACGCAGTTCAACGAGAATAAATCCACGGTCGCGGAGGAGCTAAGTTCCCTGTCGACCGCGCAGAGCGCACAGGCCAGCAAAATCAGCGGGCTGGAAACTTCGCTCGGGAAAAAAGCCGATGCAACCGCGCTGCAGTCACTCACGCAAAAAGTGGAACAGCAGGGCGGCACGTTAACCAGCCAGGGCAATTCGCTGACCTCGCTGACCAACCGCGTAGGAAAAACTGAATCGGGCGTTTCTGTAAACAGCAGTGCTATCACTGGCCTGCAGTCCAGTGTCAGCAAGCAGGATAAGACGTTAACCAGCCAGAGTCAGGCGCTCACAAAGCTGCAGAATGACCTGACCACGACGAATGCCAGCGTCAATAAGAAGGCGGAAGCCAGCGCGCTACAGACACTGCAAAACACAGTGACTCAGCAGGAAAAAGCGATATCTGCATCAAACAGCAGTATAACGTCCCTACAGACGTCCATTAACCGCCGCACGGTGTTTACCATCACATCACGAGGCAACGGGTCGAGTGCGAAGGATGGAGTTTTTGATGAGTCTGGAAATAAGCTTTTTGGCCCGAGCCGAAGTTATTCGCTGGTAACATTTAAGACAAACAGCAACGGTTCAACCTCTATTGATACCAGTAAGACTTATGATCTTTTTGGCTCGGTAAACAACGGCAAGGCTATGTCAGACGACATTGCCGCTCTTGCTAATGGCGTCTATACATGCGTCCTGACTAATGATGAGCCTACTGGTTATCGTTCTTCTATTACCTCAGCTATTGAGCTGCTTGGCGGGACAACGGAGGTCATTAATTCGCTACCGTATCGCGGAGCGTACATTCTGCTTGGTCGCAAAGGAATGAAACCGGGGGATGGTCTTGAACTCCGGGCGCCCACCGGCGGCGATCAGGGTGCTTTTATCTCGACGTCAGTTGAGTTTGTGAATGGGGTTATGCAGGGGCTGGGAGCCGCAGGTGGCGTGATGATGAAGGCAGAAGCGAATGCTTCTGCGATAACAAATCTTCAGAACACCGTGACCCAGCAGGGCAAGGATATTACTTCAGCCAGTAGCGCTATCACCAGCCTGCAGAATGGATTGAAGTCGGCGAATGACACCATCAGCAAAAAGGCTGACGCAACGGCGCTGCAGAGTCTGCAGAATACCGTAATCCAACAGGGGAGCAAGCTGACCACACAGAGCAATGCGATCACGTCACTGGAAAACAACCTGGGTGTGACAAATGCAAATCTGGACGGTTTACGTGGCATGGGCGGAAACCTTGTAGAAAACGGTGATTTTGCTCAGGGAGTGGCGTGCTGGGGTCTTCAGCAGGGTGGCCAGGATACGGTAACGTTTGGCAATTTTGGCGAGAGCGCAAAAGGCGCGAAACTGGTGAAAATTGGCTCCACTTCGCCTGGTATTTTTGTGGGCAAAAAGCGCCCGATACCGATTACCGGTCTGCGTAAATATCGCTTTGTAGTACGCGCTAAAGGTGTGAGCGGTGCTAAAAATATGCTTCTGCGCCGGTGGAATTTTGCTGGTGGTAAAGAGGGTACGTATGAGGATAAAAACATAATTCTGGATGCAGGATGGAAAACCTATACGTGGAATACCTTACTGACTCCCGATACTGGCGTAGACGCGCATGCGTTCGGTCTGTATTGCCACCCAAATGCTTCTGAGATCTGGATCGACAGCTTCTATATCTTTGATATCACCGATGAGGTGAATATTGCCGCTAATGCGACAGCATTATCTGCGTTAAGTACGACTGTCAGCAACCAAGGAAATTCTCTTACAAGTCAGAGCAATAGTCTTACATCTCTCAGCAATAGCATTGGCACATTACAGGCACAGGTTGGTAACCCGTGGTTTGATGGTTCCCTCGAAAGCTATGCCGATGGTGCACAGGTTGGAAACACTAATCAGGCCAGTGTTACAACTGCACAGAAGTTTACCGGTTCTAAGTCATTACGAGTAAAACGTCTGGCAAATGAAGCTGGAAACAGTGACAAGTTTATTGGCACTCGCTCCGCCGTTCGTGAGAATGGCGTCTTTCGTATTGAGTTGTGGGCTATGATGCCCGCAAACCAGACACCTTCTGGTGGCTGGTCAACGATTGTCGGGATCAACGTCAGAAATGCAGCTGGTGCCAATGCCTGGCAAACCGCCATTACTATCAATGAAGCGAGTCTCGGTGGTCGCGATAAGTGGGTCAAATTCTCAGGCAAATGCACTCTGCCATCAGGAAAAACTCAGGGCGTTGTTTGGATATCGTGTCGTGGTGCGACGGGGAGCGGAACGCCTGGCTATGAGCTGTATCTTGATGACGTTGTTATCACGGACATTACAGACGCGAATGAAGCGCAGAACCTTGCCAGTGCAAACGCCTCAGCACTTACGACTTTAACCAGTCGAGTGACAAAAGCGGAAGGTACGATTACTAGTCAGAGCAGCAGCATCACAAAACTGACCAATGATCTGTCGACGACGAACGCGAACGTTAACAAAAAAGCTGATGCTACCGCGCTGACTACATTACAGAACACTGTGACTCAGCAAGGTAAGGATATTAATTCAGCCAGTAGCGCTATCACCAGCCTTCAGAATGGATTGAAGTCGGCGAATGACACCATCAGCAAGAAGGCTGACGCAACGGCGCTGCAGAGTCTGCAGAATACGGTAACCCAGCAGGAGAGCAAGCTGACCACACAGAGCAATGCGATCACGTCACTGGAAAACAATCTGGGTGTGACAAATGCAAATCTGGACGGTTTACGTGGCATGGGCGGAAACCTTGTAGAAAACGGTGATTTTGCTCTGGGAGCGGCGTGCTGGGGTCTTCAGCAGGGTGGCCAGGATACGGTAACGTTTGGCAACTATGGCGACGGCTCAAAAGGCGCGAAACTGGTGAAAGTTGGCTCCACTTCGCCTGGTATTTTTGTGGGCAATAAGCGCCCGATACCGATTACCGGTCAGCGTAGATATCGCTTTGTAGTTCGTGCCAAAGGTGTGAGCGGTGCTAAAAATATACTGTTACGTCGGTGGAATTACTTTGGCGGCAAGGAAGGGGTTTATGAGAATAAAGCTTTAACTCTGGACGCAGGTTGGAATACCTACACCTGGAATACCTTGCTGACTCCTGAGAGTGGTGTAGATGCGCACGCATTCGGTCTGTATTGCCATCCTTCAGCGGCAGAAATCTGGATAGATTCGTTCTATATTTTCGATATCACTGATGAGATGAATATCGCATCTAACGCTTCTGCCGTTTCTGCACTGGATACGAAAGTCACGAAGGCAGAAGGAAATATAACCAGCCAGGGCAACGCGATTACCAGGCTGAATAACGATCTGGCCACGATGAATGGCAATGTGAATAAAAAAGCTGATGCCTCAGCATTGACCGCCTTAACAAACCGTGTGACAGAAACAGAGAAAACAGTTTCCACTCACACATCATCTATTACCAGGTTACAGAGCGATCTATCCACCACAAACGGAAACGTGGCGAAGAAGGCTGAACAGACTGCGCTCAATGCGCTGAGCAGCCGGATGACTCAGACCGAAAATAATGTGACATCTGCCAACAGTAATATCACCTCTCTGACTGCGGCTGTTCGCGCCGGGAACGCATCCAGTGGCGATCTGGTTTCCAACCCGACATTTGATCCTGCATTTAGTCAAATGGGGTTCAATGTTGTGTCATCGACTTCGTCCGGTGTTCCGACAGGCTGTCCATTTGCTAATGTGGCAAAACTGGCTGCTCGTGACCATCATCCGAACTGGGCAGCAATTCCAGCTACGCTAAATGATGTTTTCGAAATTTCCGCTTTGGTTGCCTGCGGCGCTGGCAGCGCTGATTTCAACTTCTATATTGGTACCGCGACCAGCTCAAATGGCAGCATAGGATCGCCTCTTGCTACTGGCGGGAATACGAAAAAAACCACTGCGTGGACGCGCGCAACATGGAAGGTAAAAGTCACTCAGACGATGGTTGATCGTGGATACATCAGGCCGTTTCTGCAAATCAACCAGAGTTCGCCTTTCGGGACTATCTGGTATGTGACTGACTGGCATTTTCGCAATATAACGGCAGCATACCAGGCGCAAAACACCGCTGATGCTACTGCCAAAGCTCTGGATACGCTGAGCAATACGGTTACACAGCAAGGGAAAGATATTTCCAGCGTTTCGCAGCGTGCCACAAACTTAGAAAATAGCCTTAAAACCACAAATGATAATGTGAATAAGAAGGCTGATGCTGCCGCATTCCAGACACTGCAGAGTACGGTAACAGAGCAGGGCAAAACGCTGAACTCTCAGAGTAGTTCGATAACTACTCTGAATAACAATGTTAGTACGACTAATTCCAATATCGATAGTCTGCGAGGCCTTGGCGGAAACCTTGTAGAAAACGGTAATTTTGCGCAAGGTGCAGTCGGTTGGGGTCTGCAGCAGAATGCTCAGAACCCGATAACGTTTGGCGATTACGGAGATGGCGGAAAAGGGGTTAAGCTGGCCAAAGTGAACACGACAACTTCACCAGGTATTTTTGTCAGCAATAAGCGTCCTTTTCCCGCCAATGGTCAGCGCAGATATCGCTTTGTAGTTCGCGCTAAAGGCGTGAGCGGCGCTAAAAATATGCTTTTACGTCGTTGGAATTACTCTGGTGGTAAAGAGGGGACGTATGAGGATAAAACTCTGACGCTTGATGCAGGGTGGAATACTTATACATGGAATACCTCTCTGACTCCTGCCAGTGGTGTAGATGCTCATGCCTTTGGACTGTATTGTCATCCAACGGCAGCTGAAATATGGATCGACAGTTTCTATGTTTTTGATATCACTGATGAGATGAATAATTCTGCCAATGCTACGGCACTGTCATCTCTTCAGAATACTGTAACCCAGCAGGGTAAGGATATTACTGCGTCAAACAGTAATGTGACTTCGCTACAGGCATCATTGGGACGTCGTACGGTTTTCACTATTGTTTCAAAAGGTAATGGCTCAAGTGCAAAAGAGGGGATTTTCGATGAATCTGGAAATAAACTTTTTAGTCCGGGACGAAGCTATGCGCTGGTAACATTTAAGACAAACAGTAACGGTTCAACATCTATAAACACCAGTAAAACGTATGACGTCTTTGGTTCTTCAGCTAATGGTAAGACGATGTCGGACGATATTGCGGCCCTGGCTAATGGTGTATATGTATGCATCCTCACTAATGATGAACCTACTGGATATCGTTCTTCTATTACCGCAGCATTTGAGCTTTTAGGCGGTACGACTGAAGTCATTAATTCTTTACCATATCGTGGAGCCTACATTCTGCTTGGCCGTAAGGGTATGAAAGCTGGTGATGGTCTTGAATTGCGATCACCTACTGGTGGTGATCAGAATGCTTTTATCTCGACGTCAGTTGAGTTTGTGAATGGTGTAATGATGGGATTAGGCGCCGCAGGTGGCGTCATGATGAAGGCGGACGCTAACGCTTCCGCAATTACTGCTCTTCAGAACACGGTTACGCAGCAGGGTAAAGATATTACTTCGGCCAGTAGTTCTCTTACAAGTCTGGAAAATAGTCTGAAAACGGCGAATGATAACATCAGCAAAAAAGCTGATGCAGCGGCAGTTACGGCTCTAACTAATCGTGTTTCCAAGACAGAAAATACTCTATCCAGCCAAAGTGAAAATATTACGAAGCTAACTAATAATCTGAATGCAACTAACGAAAACGTTAAACTAAAAGCCGATACGTCAGCGTTAAATGCTCTAACTAATCGAGTGGCAACAGCGGAGGGAAAAATTACTTCAGATGGAACAGCGATTACAAGTCTTAATAACAGTGTTACTAACTTAAATAATACGAAAGCCACTGTAACAGCGTTAAATGCCCTTACAACTCGTGTCACGGCTGCAGAAGGGAACATTAGTTCTCAGTCGACTTCGATTACGAATTTAACAAGTTCACTAGACGCGACAGCGTATCAGGGGGTTGGGCTAAATCCTAATGGTCGATTTAACACTGGTCTTCAATGGTGGTCTTATGCAGCAGGAACTGGTGGAAGCATTGATTGGGCCGCGAATATAGGGGAAGACGGCTCAGCTGGTGTCAAAATGACAAAGGCCGGAACAGGTAACCCTGTGATTCGAACTAACGGAAGTTCTGACAGTAAGACATCCGGTACATTTGAACTCTATCCGTTGCAAAATACCTCTGGGGGTAACGTTGGTCGTCCAATAATCGTTAGAGTGAGAGCAAAAGGTGTAAGCGGCGCAATGAATTTGATGGTTCGTTTTATAGAGTACCCCAATAGTGGTGCATTCTCATACGCGAACGATAAGACTCTGATATTCACCACCGCTTTTTCAACGCAAATAGCAAAATTTACTGCTAAAACAACAACGGTTCGCGGACGTATTGAGGTGTTTTGTTACCCGGCAAACGCGTCGGTCATTATTTCCTCTATCGTGGTGGAAGATAACACGGCAAACGAAGCTAAAGCAGATGGAACTGTTACCGCAAAGGCGGTGGATGTTCTCACTGCCGATGTAAAGATTAACAAAGGCAATATTGAAAGTAATAGTAAAAGTCTCACTTCACTCATCAATGAAGTAAAGGGGAAAGCGACCTCATCAGCATTGAGCACTTTAGAGAGCAAGGTAAATATACAAGGAAAAGATGTAGACTCTCATACCAAACAACTTTTACAACTAAATGCAACTGCTGGAGATAACACGGCGAAGATTAAGCAACAATCAGAAACAATAGCAAGTCTGGATAAAACTGTATCTGCATCGTGGACATTGAAAGTAGAGGTAGATAGCAAAGGAAATAAAATTGTTGGCGGAGTTGTATTAGGAGCTGATAGCACAGGGACAAGTCAGTTTCTCATCAATGCAAATCGCCTTGCTCTTATTAACAATGCTAATGGAGCAGTCTCGACACCGTTTGTTGTTGATAGTGGCGTGACTTACATGAATGCCGCTTATATTAAAAACGGCTCCATAACCAGCGCAAAAGTAGGAGATATTCAGTCAAATAACTACGTAGGAGGGAGTCAGGGCTGGCGTATTACTAAATCGGGAGCCAGCGAATTTAATAATGTAGTCGTGCGCGGGGAAGTTCATGCTAACAGTGGAACTTTTACCGGCACCGTGCACGCGACTGACGGCTATTTTAACGGCACCGTTTACGCTAATAAGATTGAAGGCGATGTGATGATTGCGGAGTCGAACACAATTCCTCTTAAGAACTACAGCGATGTGAACGCTGGCGACTACGAGATTCTGAAGATCAACGGGGATGACTTCGACCGAAGCATTGACACTAACCTTGTTGTTCAAGTCGGCTCTGGGTTCCGTAACGAGTTCAAGGTAATCGTCCAGACACCCGGAAGGGCTGAGCGGGAGTATTACTCCATCGACACCGGAAATAACGGCGGGGTGAGAGCTTATGCGATTCGCGGCTTCGATCTTCCGGCTGCTGGTAAGGGGCAACAAAACAGGATTATCGTCCGTGTCAGGGATAGCGGTCGCGCCAGCGGAATTATGACCTATACGCCTTATGTCCCTCGCTTTGATGGGAAATCGTTCGACATCGACTCTAACGGTAACACTATTAACCGAGGCTACCTTCGCGAACGAGCCTACATTGCGGTATTCCGCAAAGGTAACAGGATTGTCGCTTAACTCTCAGGAGAGGCCCCTAAAGGGGCCAAAATCAATATGGCCACTATATTAGCAATCAGCATGCGGCGCGAATCGCATCCAATTTATAACCAAGAGGTCTGCTGACAAGCGGACCGTCGAATCATGCTTCAGTCAGCCAAAAATCAGCCTCTTCAAACACCACCTGAGTGGCCCGGCTGATTTGATTTTTCTCATGTTTGCTGGCATCAGTGTCGATGGAAGCCAGCGCTATCATGGGGTTCACGCTGATATAGGCATCCGGAAAAATATGATGAATTATTTTCTTCGGTTAGAGATTGGAAATCTCTTAACCACTCGATAAATAAGTAACTTTGCAAAGAATCAGAATTATTTAATGGTTTCTGCCATGATGTCTCACATGCTGTCTGGATTAGGGCAGTTAACATGGGCTCTATTCCAGTACAACGGTATCCGACAGGTAGTCTCCTTTTCCACATCTAAGGTCCCACCATAAAGGAGTCCAAAAAATTTGCTAAAAAATGTTAATACAGCGCATAAATACGTACTTCGCCTCTCGACGCGGCGCGCCGAGCTGCCTATTATTCTTGGGCTTGTTCATTTTAAGATGTATCTGAGGGGAGAGAAGATGCGAGCTGCGTTTTTAGTGGGATGTGCTGCGCTGTTGCTTTCAGCATGCAGCAGTAATGATGAACCTGTTCAGCAGGCAACGGCGGCGCATGTGTCGCCAGGGATGCGTGCCGCGATGAGCAGCACCGGCCAGGCAAACTGCGCGATGGTCGGCGGCTCGTTATCAGTGGCGCGTCAGCTTGACGGCTCGGCTATCGGCATGTGCGCATTGCCAAACGGCAAACGCTGCAGCGAGCAGGCGCTGGCGGGCGGAAGCTGCGGTAACTATTAATTCACCAGGTCGGCGAGCTTATACACTAGCGTCTGGTCGGCGGTCGCCAGCGTCAGCTGGGTTTCGGTCAGGTCGACCTGCGCGCCTTCACGCAGCATTTTACCAAGCGTGGTGTCCAGAGCGTTCAACTGAGGGTCCGCGCAGAGCATGCGCGTCATTGCCAGTTCTTTAACCTTCAGCGCGCCGTCAGAGACTTTTCCCGTGCCGTTGAATTGGTTGCACATATTGCCTGAAACGTACATTTTGCCGGTAATCGGCATCTCTTCGCCGAAGCTCAGTTCCAGCGGTTTATCAGCAGCATTCAGCGATTGTCCGTTAACGCTGGTCAGTACAAAACGGTGGTGCTGAAGCTGTTCCGCCCTGGTCGAAACCTTGCTGTTATACACGCAGCCAGATAGCAACATTCCTGCCGCCAGAAGCGCAGCAAACTTGTTCATTTAATCTCCATAAATATTTATCGCATTAATGAATGAAGGGGATTGTAACTTTATCGCAGGCAATTTCTGTGAGGATTGTCTGAATGTGCCCCCCGCCAGGGGGGAGCACAAAAGGCGAAGGAAAATCAGACCAGTGCGTTAGGGCAGGTTTCGCCAGCATCCACCTGACGCAGATTGTCGAGAGTGGTTTGCGAGATACTGATCAACGCTTCCGCGGTCAAAAACGCCTGATGACCGGTAAACAGGACGTTGTGGCAGGCGGACAGACGGCGGAAAACATCGTCCTGAATAACGTCGTTAGACTTGTCTTCAAAGAACAGATCGCGTTCATTCTCATACACGTCCATCCCCAGCGCGCCAATTTTTTGGTGCTTCAGAGCATCGATTGCCGCCTGAGAGTCAATTAGCGCACCGCGGCTGGTATTGATGATCATCACCCCATCTTTCATTTGATCGAACGCGGCATGGTTCAACAGATGATAGTTTTCATCGGTCAGCGGACAGTGCAGGGAGATAACATCGGACTCTTTGTACAGCGTTGTCAGATCGACATACTCCCCCCCCAGATCCAGCGCGGCCGCGCTGGGATACGGATCAAATGCCAGCAGACGCATACCGAAGCCTTTCAGAATGCGCAGCGTGGCGACGCCAATTTTACCGGTACCGATAACGCCGGCGGTTTTACCGTGCATAGTGAAACCGGTCAACCCTTCCAGAGAGAAGTTCGCGTCGCGGGTGCGCTGATAGGCGCGATGAATGCGGCGGTTCAACGACATCATCATACCGACCGCGTGCTCAGCGACCGCTTCAGGGGAATAGGCCGGAACGCGCACTACGCGCAGGCCCAGCTCTTTAGCGGCGTCGAGGTCAACGTTATTGAAACCGGCGCAGCGAAGCGCAATGTACTTCACGCCGTGGGCTTTCAGTTCTTCAAGTACCGGACGGCTACCGTCGTCATTAACGAAGATACACACCGCTTCACAGCCGTTGGCGGTTTTGGCGGTCTTTTCGGTTAACAGGAAGTCAAAAAATTCCAGTTCAAAGCCGTATGTATCATTAACATGCTGCAGATACTTCTTGTCGTACTGTTTTGTACTATACACAGCGATTTTCAT

Protein sequences of DBSCAN-SWA_2

>NZ_CP046115|2457315:2487419|2467156_2467699_+|WP_154680296.1|DBSCAN-SWA
MSKDDIFNAILDKEGGYVNHPDDRGGPTNWGVTQATARAHGYDGDMRKLTRQQALDILHADYWIAPRFDQVAEISTAIADKLCDAGVNMGPSQPGKWLQRWLNAFNNRGVLYPDLIIDGVIGPRSLNALNHYLIRRGSEGELVLLRGLNCSQGQYYLELAERRAANESFIYGWLRMRVSM
>NZ_CP046115|2457315:2487419|2458961_2459174_-|WP_154680290.1|DBSCAN-SWA
MHHHPVKSSRITSVAYDESSGILEIRFRDNKTLQYIGVPARIFRDFLQVVSKGRFYDGVIKGKFTERRRA
>NZ_CP046115|2457315:2487419|2485863_2486304_-|WP_154680308.1|DBSCAN-SWA
MNKFAALLAAGMLLSGCVYNSKVSTRAEQLQHHRFVLTSVNGQSLNAADKPLELSFGEEMPITGKMYVSGNMCNQFNGTGKVSDGALKVKELAMTRMLCADPQLNALDTTLGKMLREGAQVDLTETQLTLATADQTLVYKLADLVN
>NZ_CP046115|2457315:2487419|2467753_2468173_+|WP_154680297.1|DBSCAN-SWA
MYTSNDLTLSMFYSSAIAEETGNKIATLTVQTMGPSAEILQISKLHCITDETRTKNYSIGEQFIANGSDPLLAAIETWWRDNSAILIQELMVEVMDFISGNINQNATWIGQYGMKIFENEPVTKRMPDSVLQNGSSTDA
>NZ_CP046115|2457315:2487419|2469746_2470856_+|WP_154680300.1|tail|DBSCAN-SWA
MASDTTMTLRMNNSELEKNIQLLDKYQQKVTVANRKSEEFNKTFRGATDIQKKHTDSLKRLMQTLPLPPARMGSILQEMIKKSEEETYNITSGPKSYWDSLTGMDSTSNFELGNTAKVFQSGVEPEASPGDHNQKGSKSDWLGGLIAGAKEAWDKFLEDGKNVHGKLKELAKDAFSSMGNSLVEYITTGKANFNDFLMTFLKGTLKMLSQLMLVKAMEASFNAMSNSGIGWISSIGKIFMGHSAGGYTGDGGKYEPKGIVHGGEFVFTKEATAAIGIGNLYAMMRGAQGYAGGGYVGTALMQGLGSSGSGPLTVQTSVLIQNQSTEPQATDNNGALNRAWQQTIDRSVRAGVANELRPGGLIWNANHGR
>NZ_CP046115|2457315:2487419|2466494_2466887_+|WP_154680294.1|DBSCAN-SWA
MSDPVSGTSAFVAGGLMGAGMFGLVTGIDYGVVFGAFAGAVFYVATAVNIPRFRLAAYFITSFIVGVLGAGLIGTKLASWTGYNERPLDALGAVLLSALIIKILTFLNNQELTDLYKILTRNNNGRSNGK
>NZ_CP046115|2457315:2487419|2466054_2466417_+|WP_154680293.1|DBSCAN-SWA
MSRKTPFNGSAAGRRRAQRSHLQNSAALSSDFIHRPTPCRAQIQAKGKHYTPERIEDALPIKFIAQDVFWHREEYKRQILRATLIYQQEFAHRYIEPGTYLCHRAIYALGLQKRKKITAR
>NZ_CP046115|2457315:2487419|2457315_2458251_-|WP_154680288.1|tRNA|DBSCAN-SWA
MLQNQEISKKEKYNIDKLQKRLRRNVGEAIADFNMIEDGDRIMVCLSGGKDSYTMLEILRNLQKSAPISFSLVAVNLDQKQPGFPEHILPEYLEQLGVEYKIVEENTYGIVKEKIPEGKTTCSLCSRLRRGILYRTATELGATKIALGHHRDDILQTLFLNMFYGGKMKGMPPKLMSDDGKHIVIRPLAYCREKDIERFSQAKGFPIIPCNLCGSQPNLQRQVIADMLRDWDKRYPGRIETMFSAMQNVVPSHLSDVNLFDFKGIKHGSEVVDGGDLAFDREEIPMQPAGWQPEEDDAQLDELRLNVVEVK
>NZ_CP046115|2457315:2487419|2470877_2471225_+|WP_154680301.1|tail|DBSCAN-SWA
MAIETFSWPTQIQAGLQGDFNFTVREARFADGYQQVVGDGLNFEKQSWPVTLTGEKEEILAILEFMRRHVTKSFIWNSPTGESGLYRVSPDSLKLSPLSSQVMTVTATFNQAYAP
>NZ_CP046115|2457315:2487419|2464998_2465535_+|WP_154682704.1|DBSCAN-SWA
MVELIESSFNLPRGWMDGITGNVDVEKEPVEDSPQMNYVIEVLDAQASAGPGCIVSSEVDETVSSITYDSVGALRLFGNRPAEHIKVITVSGDSMSGTIETGDYIFIDVSKDYFEGDGIYVFSFKGAVLVKRLQFTADGLLVHSDNSKYADWTIGESHEQYLKIIGRVIYSHSVKRFV
>NZ_CP046115|2457315:2487419|2466876_2467149_+|WP_154680295.1|holin|DBSCAN-SWA
MESNLPALINSVLCFFITVNLMFYRRVQDRTYRPWISYTAYLLVITYASIPFRYLFGLYESTHWLVVIVNFFVFIAVFLVKGNIAHLIDK
>NZ_CP046115|2457315:2487419|2459325_2460474_-|WP_154680291.1|DBSCAN-SWA
MKRKVLALVIPALLAAGAAHSAEIYNKDGNKLDLYGKVDGLHYFSDDNNSDGDQTYVRFGFKGETQINDRITGYGQWEYNVQANNTESSGDQAWTRLAFAGLKFANYGSFDYGRNYGVLYDVEGWTDMLPEFGGDTYSKADNYMTGRANGVATYRNSDFFGLVNGLNFALQYQGKNENQSSHEYQEGTANSNGRNVKNANGDGFGISSSYDLGMGISAAAAYSSSDRTNEQTHASTAGGDKADAWTAGLKYDANSIYLATMYSETRNMTPYGNNSDTIANKTQNVEVTAQYQFDFGLRPAISYLQSKGKDLVMQGNAANPAGNTGDKDLVKYVDIGATYYFNRNMSTYVDYKINLLDDDDTFYKDNGISTDNVVALGLVYQF
>NZ_CP046115|2457315:2487419|2485594_2485867_+|WP_154680307.1|DBSCAN-SWA
MRAAFLVGCAALLLSACSSNDEPVQQATAAHVSPGMRAAMSSTGQANCAMVGGSLSVARQLDGSAIGMCALPNGKRCSEQALAGGSCGNY
>NZ_CP046115|2457315:2487419|2473536_2484987_+|WP_154680305.1|DBSCAN-SWA
MEKISMTQHLIKGCKGGSSSPRTPTEQPDDLQSVAKAKVLLALGEGEFAGALTAKDIYLDGTPLENSDGSQNFSGVAWEFRPGTQAQNYIQGIPGSENEINVGMEVSSKTAWSRSFSNTQLSAVRLRLKWPSLLKQEDNGDLVGNTVSYAVDLQTDGGSWQTVLESAVSGKTTAGYERCHRIDLPRSTTGWVLRLRKVTQDANSSKTGDVMMLQSYAEVLDAKLRYPNTALLYVEFDSRLFNGSIPKISCSPRGRVIRVPDNYDPETREYSGIWTGAFKWAWTDNPAWIFYDLIVSDRFGLGNRLTSENIDKWTLYQVARYCDEPVPDGKGGDGTEPRYLCNVYVQNRNDAYTVLRDFAAIFRGMTCWSGDQVIALADMPRDIDYTYTRANVINGRFQYASSSSKTRYTNALVSWSDPENEYADAMEPVFEQPLVARYGFNQLELTAIGCTRQSEANRKGRWGILTNNKDRVVTFSVGLDGNIPQPGYVIAVADEMLAGKVNGGRTSEVDGCVITLDRQTEAKAGDRLLLNLPSGVTQSRTIEDVNGHVVTVTAEYAELPETECVWAIESDSLRVQQYRVVSVKDNNDSTFTISAAAHDPDKYARIDTGAIIDSRPISVIPPGNQNAPANIVVESYSVVNQGISVETLQVHWAPVKNAIAYEAQWRRNEGNWVNVPRSSVTSFDVGGIYAGRYTVRVRAINAAEVSSGWAYSDEKILTGKIGMPVAPIALTTTSLLHGVELQWAFPDGAGDTQKTELQYSPNPNGSGAMALSDVTYPGKTYQQMGLQIAATFWYRARIVDRLGNESPWTSWVQGMASDDIDEYYDKLTDAIKDTEAWQEAQRDIGDTHKALTETADAIRDEVAQQVTDIHQNIDDTVGGLRKQVDGQIESVNKSITENIDLVNQTLNDNISAVNQSLSDAVTEMNTSVDQQIADVNKVLAEGDSALKSQLQTVENSLKQSIAQANTGWDKAVKQETADRIADVNAKAAQAADQLLNEKNERVAAIDNLQTVIQDGDESLARQIAEISAGSGQQFDSFSIWYFDKDNEGWTEDDAGQVPMQITDEGWLKASNSTASCRSPNGQTIPASSYRTIMLRIKRVGNPVWKGRFYWIGADEQGWNDARSVTIAEQEFDGDGISVVAIPDVNWNASGTVRRFRIDLAQGQNADNYFLIHWISVGRPAPAASTAALRNEEMARTQADEAEAMKRSTLAAQIRGTTDSNSLSDLRSGLLYQEMNARITADRAEVVARESLQTQFNENKSTVAEELSSLSTAQSAQASKISGLETSLGKKADATALQSLTQKVEQQGGTLTSQGNSLTSLTNRVGKTESGVSVNSSAITGLQSSVSKQDKTLTSQSQALTKLQNDLTTTNASVNKKAEASALQTLQNTVTQQEKAISASNSSITSLQTSINRRTVFTITSRGNGSSAKDGVFDESGNKLFGPSRSYSLVTFKTNSNGSTSIDTSKTYDLFGSVNNGKAMSDDIAALANGVYTCVLTNDEPTGYRSSITSAIELLGGTTEVINSLPYRGAYILLGRKGMKPGDGLELRAPTGGDQGAFISTSVEFVNGVMQGLGAAGGVMMKAEANASAITNLQNTVTQQGKDITSASSAITSLQNGLKSANDTISKKADATALQSLQNTVIQQGSKLTTQSNAITSLENNLGVTNANLDGLRGMGGNLVENGDFAQGVACWGLQQGGQDTVTFGNFGESAKGAKLVKIGSTSPGIFVGKKRPIPITGLRKYRFVVRAKGVSGAKNMLLRRWNFAGGKEGTYEDKNIILDAGWKTYTWNTLLTPDTGVDAHAFGLYCHPNASEIWIDSFYIFDITDEVNIAANATALSALSTTVSNQGNSLTSQSNSLTSLSNSIGTLQAQVGNPWFDGSLESYADGAQVGNTNQASVTTAQKFTGSKSLRVKRLANEAGNSDKFIGTRSAVRENGVFRIELWAMMPANQTPSGGWSTIVGINVRNAAGANAWQTAITINEASLGGRDKWVKFSGKCTLPSGKTQGVVWISCRGATGSGTPGYELYLDDVVITDITDANEAQNLASANASALTTLTSRVTKAEGTITSQSSSITKLTNDLSTTNANVNKKADATALTTLQNTVTQQGKDINSASSAITSLQNGLKSANDTISKKADATALQSLQNTVTQQESKLTTQSNAITSLENNLGVTNANLDGLRGMGGNLVENGDFALGAACWGLQQGGQDTVTFGNYGDGSKGAKLVKVGSTSPGIFVGNKRPIPITGQRRYRFVVRAKGVSGAKNILLRRWNYFGGKEGVYENKALTLDAGWNTYTWNTLLTPESGVDAHAFGLYCHPSAAEIWIDSFYIFDITDEMNIASNASAVSALDTKVTKAEGNITSQGNAITRLNNDLATMNGNVNKKADASALTALTNRVTETEKTVSTHTSSITRLQSDLSTTNGNVAKKAEQTALNALSSRMTQTENNVTSANSNITSLTAAVRAGNASSGDLVSNPTFDPAFSQMGFNVVSSTSSGVPTGCPFANVAKLAARDHHPNWAAIPATLNDVFEISALVACGAGSADFNFYIGTATSSNGSIGSPLATGGNTKKTTAWTRATWKVKVTQTMVDRGYIRPFLQINQSSPFGTIWYVTDWHFRNITAAYQAQNTADATAKALDTLSNTVTQQGKDISSVSQRATNLENSLKTTNDNVNKKADAAAFQTLQSTVTEQGKTLNSQSSSITTLNNNVSTTNSNIDSLRGLGGNLVENGNFAQGAVGWGLQQNAQNPITFGDYGDGGKGVKLAKVNTTTSPGIFVSNKRPFPANGQRRYRFVVRAKGVSGAKNMLLRRWNYSGGKEGTYEDKTLTLDAGWNTYTWNTSLTPASGVDAHAFGLYCHPTAAEIWIDSFYVFDITDEMNNSANATALSSLQNTVTQQGKDITASNSNVTSLQASLGRRTVFTIVSKGNGSSAKEGIFDESGNKLFSPGRSYALVTFKTNSNGSTSINTSKTYDVFGSSANGKTMSDDIAALANGVYVCILTNDEPTGYRSSITAAFELLGGTTEVINSLPYRGAYILLGRKGMKAGDGLELRSPTGGDQNAFISTSVEFVNGVMMGLGAAGGVMMKADANASAITALQNTVTQQGKDITSASSSLTSLENSLKTANDNISKKADAAAVTALTNRVSKTENTLSSQSENITKLTNNLNATNENVKLKADTSALNALTNRVATAEGKITSDGTAITSLNNSVTNLNNTKATVTALNALTTRVTAAEGNISSQSTSITNLTSSLDATAYQGVGLNPNGRFNTGLQWWSYAAGTGGSIDWAANIGEDGSAGVKMTKAGTGNPVIRTNGSSDSKTSGTFELYPLQNTSGGNVGRPIIVRVRAKGVSGAMNLMVRFIEYPNSGAFSYANDKTLIFTTAFSTQIAKFTAKTTTVRGRIEVFCYPANASVIISSIVVEDNTANEAKADGTVTAKAVDVLTADVKINKGNIESNSKSLTSLINEVKGKATSSALSTLESKVNIQGKDVDSHTKQLLQLNATAGDNTAKIKQQSETIASLDKTVSASWTLKVEVDSKGNKIVGGVVLGADSTGTSQFLINANRLALINNANGAVSTPFVVDSGVTYMNAAYIKNGSITSAKVGDIQSNNYVGGSQGWRITKSGASEFNNVVVRGEVHANSGTFTGTVHATDGYFNGTVYANKIEGDVMIAESNTIPLKNYSDVNAGDYEILKINGDDFDRSIDTNLVVQVGSGFRNEFKVIVQTPGRAEREYYSIDTGNNGGVRAYAIRGFDLPAAGKGQQNRIIVRVRDSGRASGIMTYTPYVPRFDGKSFDIDSNGNTINRGYLRERAYIAVFRKGNRIVA
>NZ_CP046115|2457315:2487419|2486429_2487419_-|WP_154680309.1|DBSCAN-SWA
MKIAVYSTKQYDKKYLQHVNDTYGFELEFFDFLLTEKTAKTANGCEAVCIFVNDDGSRPVLEELKAHGVKYIALRCAGFNNVDLDAAKELGLRVVRVPAYSPEAVAEHAVGMMMSLNRRIHRAYQRTRDANFSLEGLTGFTMHGKTAGVIGTGKIGVATLRILKGFGMRLLAFDPYPSAAALDLGGEYVDLTTLYKESDVISLHCPLTDENYHLLNHAAFDQMKDGVMIINTSRGALIDSQAAIDALKHQKIGALGMDVYENERDLFFEDKSNDVIQDDVFRRLSACHNVLFTGHQAFLTAEALISISQTTLDNLRQVDAGETCPNALV
>NZ_CP046115|2457315:2487419|2485108_2485267_-|WP_154680306.1|DBSCAN-SWA
MIHHIFPDAYISVNPMIALASIDTDASKHEKNQISRATQVVFEEADFWLTEA
>NZ_CP046115|2457315:2487419|2471221_2471974_+|WP_154680302.1|tail|DBSCAN-SWA
MITADYQKLEPGNEIRLLEIDGSVFGMDDILYFHGHSLAHSEAEILAAGGDETRLPAKSIWWQGNEYMPWPCIIDGIESTTAGRDAQPSLKVANIDASITALCLYYDDLVQAKVTVHDTLAKYLDARNFPEGNATADPTQEKRKVYFIDAKSEETNEVIEFTLASPMDLQGIMIPTRQLHSICTWCIRNKYRSGDGCDYNGQRYFDKNNVPVTDPAQDVCNGTLSACKLRFGEDNELPFGGFPGTSLIRS
>NZ_CP046115|2457315:2487419|2468306_2468969_+|WP_154680298.1|tail|DBSCAN-SWA
MAFALPNGSTVFVGSGLSNPVSVSAVSNAEGAVFSVAENHNLKVDDVVLISSGWGIIDGLVARITAQTTNSVTISVINSSDRNFFPAHAGGGKLQKITEWTEIPQITEVAQSGGEQQYAQVQFLADDRQRNIGTFKAAKNQTFTLAHDASLPIYNVLSMADRYGQVLPLRMFVPNAKEYRYWSGVPSFDPQPVTAVNSVETVQVAFSIHSRDITFYKSED
>NZ_CP046115|2457315:2487419|2460828_2464356_-|WP_154680292.1|DBSCAN-SWA
MITIDGNGAVASVAFRTSEVIAIYPITPSSTMAEQADAWAGNGLKNVWGDVPRVVEMQSEAGAIGAVHGALQTGALSTSFTSSQGLLLMIPTLYKLAGQLMPFVLHVAARTVATHALSIFGDHSDVMAVRQTGCAMLCASSVQEAQDFALISHIATLQSRVPFIHFFDGFRTSHEINKIAPLADDTIRSLLPQDKIDEHRQRALNPEHPVIRGTSANPDTYFQSREATNPWYDAVYEHVETAMDDFAAATGRKYKPFEFYGHPQAERVIVIMGSAIGTCEEVVDELLGRGEKVGVLKVRLYRPFSAAHLLDVLPQSARAVAVLDRTKEPGAQAEPLYLDVMTALAEAFNRGERETLPRTIGGRYGLSSKEFGPECVLAIFNELNAAKPKPRFTVGIYDDVTNLSLPLPENSLPSEAKLEALFYGLGSDGSVSATKNNIKIIGNSTPWFSQGYFVYDSKKAGGLTVSHLRVSEKPIRSSYLISQADFVGCHQLQFIDKYQMVERLKPGGIFLLNTPYSADEVWSRLPQEVQATLNKKKARFFIVNAAKIARECSLGARINTVMQMAFFHLTQILPGDSALAELQGAIAKSYSSKGQELVERNWQALALARESLAEVPLRQVDASSPNRPPVVSDAAPDFVKTVTAAMLAGLGDALPVSALPPDGTWPMGTTRWEKRNIAEEIPIWKEELCTQCNHCVAACPHSAIRAKVVSPEAMENAPASLHSLDVKSRDMRGQKYVLQVAPEDCTGCNLCVEVCPAKDRQNPEIKAINMMSRLEHVEEEKVNYDYFLKLPEIDRSKLERIDIRTSQLISPLFEYSGACSGCGETPYIKLLTQLYGDRMLIANATGCSSIYGGNLPSTPYTTDANGRGPAWANSLFEDNAEFGLGFRLTVDQHRQRVMRLLSQFADKLPAELNAALHAEATPEARREQVAELRNVLANEEGAKELLTDADALVEKSIWLIGGDGWAYDIGFGGLDHVLSLTENVNILVLDTQCYSNTGGQASKATPLGAVTKFGEHGKRKARKDLGVSMMMYGHVYVAQISLGAQLNQTVKAIQEAEAYPGPSLIIAYSPCEEHGYDLALSHDQMRQLTATGFWPLYRFDPRRADEGKLPLALDSRPPSDALAETLLNEQRFRRLNAQQPEVAEQLWKDAAADLQKRYDFLAQLAGKAEKPAAES
>NZ_CP046115|2457315:2487419|2472875_2473490_+|WP_154680304.1|tail|DBSCAN-SWA
MQEHMVRIELGGILGKKFGKHHCRMVATASEAIRALCCTINGFEKFMNNSKAMGLTYAVFKGKKNISEDDIPFPISDKVIRIVPVVIGSKKAGMLQTILGVALIAVASIATMGAGGIFAAISAGSGWGTAAMLGASMALGGVLQMLSPQVPGLASQQSPENKASYAFGGVTNTTAQGYPVPLLYGKRLIGGAIISAGIYVEDQQ
>NZ_CP046115|2457315:2487419|2469041_2469353_+|WP_154680299.1|DBSCAN-SWA
MSAIFKLQPKPVFKADVVIPRAGEEDGVLNFTFKHRPIKELAELESIDEKTVSDFLLEIVDDWALSEPCTRENIGVLVDNYPGAVKAIMTTYYQELTGNREKN
>NZ_CP046115|2457315:2487419|2471975_2472689_+|WP_154680303.1|DBSCAN-SWA
MRLKVIRAIQEHARKEYPRECCGVIAQRGRIARYFPCRNIADDPLEHFVLAPEDYTQVEDWGIVTGIVHSHPDATTQPSELDKAQCDAMLLPWHIFSWPEGDLRTIYPRGELPLLERPFVLGHYDCWGLVMSYFRQQHGVELRDYRVDYPWWEDSYPDNFYHDCWYECGFREFYGPPQPGDMVIMQVQANKWNHAGILLEGNMLLHHLYGHLSQRVPYGGYWQERTVKVLRYPVKDN
>NZ_CP046115|2457315:2487419|2469400_2469661_+|WP_154682705.1|DBSCAN-SWA
MSAFGLTAEDYDDVIINVWPDIWPAFVVFRAASTQWRTSPGGVIGLDYNVLAWLMKVYDVADEVTAINDLQVMERVALNILNKLHN
>NZ_CP046115|2457315:2487419|2458445_2458880_-|WP_154680289.1|DBSCAN-SWA
MNRMILVPIDISDTELTERVIKHVESEARIDDAEVHFLTVIPSLPYYASLGMAYTAELPAMDDLKAESESRLKEIVSKFTIPEDRIHLHVSEGSPKDKILAMAKSLPADLVIISSHRPDITTYLLGSNAAAVVRHAECSVLVVR

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_154680288.1|2457315_2458251_-|tRNA	tRNA 2-thiocytidine(32) synthetase TtcA	A0A0U2S5Z2	Escherichia_phage	2.0e-138	93.0
WP_154680289.1|2458445_2458880_-	universal stress protein UspF	A0A1W6JNV4	Morganella_phage	2.1e-29	51.4
WP_154680290.1|2458961_2459174_-	KTSC domain-containing protein	NA	NA	NA	NA
WP_154680291.1|2459325_2460474_-	porin OmpC	Q1MVN1	Enterobacteria_phage	1.1e-104	55.0
WP_154680292.1|2460828_2464356_-	pyruvate:ferredoxin (flavodoxin) oxidoreductase	NA	NA	NA	NA
WP_154682704.1|2464998_2465535_+	phage repressor protein	K7PKK1	Enterobacteria_phage	1.5e-29	49.0
WP_154680293.1|2466054_2466417_+	antitermination protein	C6ZR44	Salmonella_phage	3.0e-29	55.0
WP_154680294.1|2466494_2466887_+	hypothetical protein	K7PHB9	Enterobacterial_phage	4.5e-39	68.5
WP_154680295.1|2466876_2467149_+|holin	phage holin family protein	K7PKN9	Enterobacterial_phage	1.8e-15	50.6
WP_154680296.1|2467156_2467699_+	hypothetical protein	A0A0U2I1S0	Escherichia_phage	8.9e-70	66.7
WP_154680297.1|2467753_2468173_+	hypothetical protein	Q6UAS0	Klebsiella_phage	7.7e-37	51.5
WP_154680298.1|2468306_2468969_+|tail	phage tail protein	I6PBN6	Cronobacter_phage	1.0e-75	64.1
WP_154680299.1|2469041_2469353_+	hypothetical protein	I6PDG2	Cronobacter_phage	6.1e-31	61.2
WP_154682705.1|2469400_2469661_+	hypothetical protein	A0A2H4J4F7	uncultured_Caudovirales_phage	1.7e-10	42.5
WP_154680300.1|2469746_2470856_+|tail	phage tail tape measure protein	I6PCW3	Cronobacter_phage	2.7e-52	50.0
WP_154680301.1|2470877_2471225_+|tail	phage tail protein	I6PBN7	Cronobacter_phage	1.8e-39	63.5
WP_154680302.1|2471221_2471974_+|tail	phage minor tail protein L	K7PKU0	Enterobacteria_phage	1.9e-115	75.5
WP_154680303.1|2471975_2472689_+	peptidase P60	Q6UAW4	Klebsiella_phage	8.8e-126	83.2
WP_154680304.1|2472875_2473490_+|tail	tail assembly protein	K7PM97	Enterobacterial_phage	2.1e-67	69.1
WP_154680305.1|2473536_2484987_+	DUF1983 domain-containing protein	Q6UAW1	Klebsiella_phage	0.0e+00	59.8
WP_154680306.1|2485108_2485267_-	DinI-like family protein	Q6UAW0	Klebsiella_phage	8.4e-13	70.6
WP_154680307.1|2485594_2485867_+	DUF333 domain-containing protein	NA	NA	NA	NA
WP_154680308.1|2485863_2486304_-	heat shock protein HslJ	NA	NA	NA	NA
WP_154680309.1|2486429_2487419_-	2-hydroxyacid dehydrogenase	M1HKI4	Acanthocystis_turfacea_Chlorella_virus	1.6e-69	45.4