CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP046280	Salmonella enterica strain FDAARGOS_688 chromosome, complete genome	2 crisprs	DinG,cas3,DEDDh,csa3,WYL,PD-DExK	0	18	7	0
NZ_CP046281	Salmonella enterica strain FDAARGOS_688 plasmid unnamed1, complete sequence	0 crisprs	DEDDh	0	0	3	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP046280_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP046280_1

2978500-2979017

Orphan

I-E

Consensus_repeat	Method
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CRISPRCasFinder
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CRT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	PILER-CR

8 spacers

The CRISPR arrays of NZ_CP046280_1

>merge|NZ_CP046280|1|2978500-2979017|CRISPRCasFinder,CRT,PILER-CR
GTGTTTATCCCCGCTGGCGCGGGGAACACATGTGTAAATTTTGGTGCCGTTCCTGGGTTTTCGGTTTATCCCCGCTGGCGCGGGGAACACGCGCTTGATCTCCCGTTATCTAAGGGCCAATCCGGTTTATCCCCGCTGGCGCGGGGAACACTGGCTTATAAATAAAAGGTTGAGGTGTCAGTACGGTTTATCCCCGCTAGCGCGGGGAACACACGCCATCATTGAAAGCAATCTGGCAACGTACCGGTTTATCCCCGCTGGCGCGGGGAACACATAAAATAGGAACGGCGGGGAATGAAAATACGCGGTTTATCCCCGCTGGCGCGGGGAACACAGGATGGAGACCGTCAGGCTCCGGAAACTGCCCGGTTTATCCCCGCTGGCGCGGGGAACACTACTCACAGCGTATTCTGAATATTGCAAAAGACGGTTTATCCCCGCTGGCGCGGGGAACACCCTCAGGGATCTCCGGCTCTACGCTGAACTCCGCGGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP046280|1|1|2978500-2979017|CRISPRCasFinder
GTGTTTATCCCCGCTGGCGCGGGGAACAC	ATGTGTAAATTTTGGTGCCGTTCCTGGGTTTT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCGCTTGATCTCCCGTTATCTAAGGGCCAATC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TGGCTTATAAATAAAAGGTTGAGGTGTCAGTA
CGGTTTATCCCCGCTAGCGCGGGGAACAC	ACGCCATCATTGAAAGCAATCTGGCAACGTAC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ATAAAATAGGAACGGCGGGGAATGAAAATACG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AGGATGGAGACCGTCAGGCTCCGGAAACTGCC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TACTCACAGCGTATTCTGAATATTGCAAAAGA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CCTCAGGGATCTCCGGCTCTACGCTGAACTCCG
CGGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP046280|1|1|2978500-2979017|CRT
GTGTTTATCCCCGCTGGCGCGGGGAACAC	ATGTGTAAATTTTGGTGCCGTTCCTGGGTTTT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCGCTTGATCTCCCGTTATCTAAGGGCCAATC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TGGCTTATAAATAAAAGGTTGAGGTGTCAGTA
CGGTTTATCCCCGCTAGCGCGGGGAACAC	ACGCCATCATTGAAAGCAATCTGGCAACGTAC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ATAAAATAGGAACGGCGGGGAATGAAAATACG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AGGATGGAGACCGTCAGGCTCCGGAAACTGCC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TACTCACAGCGTATTCTGAATATTGCAAAAGA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CCTCAGGGATCTCCGGCTCTACGCTGAACTCCG
CGGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP046280|1|1|2978502-2979017|PILER-CR
GTTTATCCCCGCTGGCGCGGGGAACACAT	GTGTAAATTTTGGTGCCGTTCCTGGGTTTTCG
GTTTATCCCCGCTGGCGCGGGGAACACGC	GCTTGATCTCCCGTTATCTAAGGGCCAATCCG
GTTTATCCCCGCTGGCGCGGGGAACACTG	GCTTATAAATAAAAGGTTGAGGTGTCAGTACG
GTTTATCCCCGCTAGCGCGGGGAACACAC	GCCATCATTGAAAGCAATCTGGCAACGTACCG
GTTTATCCCCGCTGGCGCGGGGAACACAT	AAAATAGGAACGGCGGGGAATGAAAATACGCG
GTTTATCCCCGCTGGCGCGGGGAACACAG	GATGGAGACCGTCAGGCTCCGGAAACTGCCCG
GTTTATCCCCGCTGGCGCGGGGAACACTA	CTCACAGCGTATTCTGAATATTGCAAAAGACG
GTTTATCCCCGCTGGCGCGGGGAACACCC	TCAGGGATCTCCGGCTCTACGCTGAACTCCGCG
GTTTATCCCCGCTGGCGCGGGGAACAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046280.1\|WP_114046795.1\|2987172_2987970_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|224158
NZ_CP046280.1\|WP_156017218.1\|2982773_2984486_-\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	unknown	unknown	gnl\|CDD\|237402
NZ_CP046280.1\|WP_001145535.1\|2980922_2981876_+\|SPI-1-type-III-secretion-system-effector-SopD	unknown	unknown	gnl\|CDD\|185277
NZ_CP046280.1\|WP_000036734.1\|2989870_2991169_-\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NZ_CP046280.1\|WP_114053080.1\|2974238_2974844_-\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
NZ_CP046280.1\|WP_000741649.1\|2972633_2973344_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
NZ_CP046280.1\|WP_023214376.1\|2974830_2976270_-\|sulfate-adenylyltransferase-subunit-CysN	unknown	unknown	gnl\|CDD\|235349
NZ_CP046280.1\|WP_023136478.1\|2981963_2982698_-\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NZ_CP046280.1\|WP_000134248.1\|2971108_2972158_-\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884
NZ_CP046280.1\|WP_000108313.1\|2986720_2987083_+\|6-carboxytetrahydropterin-synthase-QueD	unknown	unknown	gnl\|CDD\|238264
NZ_CP046280.1\|WP_000210864.1\|2991251_2992889_-\|CTP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|235437
NZ_CP046280.1\|WP_001219244.1\|2972154_2972634_-\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851
NZ_CP046280.1\|WP_156017221.1\|2984485_2986285_-\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	unknown	unknown	gnl\|CDD\|182862
NZ_CP046280.1\|WP_000372384.1\|2976279_2977188_-\|sulfate-adenylyltransferase-subunit-CysD	unknown	unknown	gnl\|CDD\|235375
NZ_CP046280.1\|WP_000517480.1\|2973362_2973674_-\|cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156
NZ_CP046280.1\|WP_156017223.1\|2993116_2993917_-\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569
NZ_CP046280.1\|WP_138019900.1\|2973864_2974221_-\|DUF3561-family-protein	unknown	unknown	gnl\|CDD\|371891
NZ_CP046280.1\|WP_023212181.1\|2977438_2978485_+\|aminopeptidase	unknown	unknown	gnl\|CDD\|182299
NZ_CP046280.1\|WP_001221538.1\|2970366_2971128_-\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
NZ_CP046280.1\|WP_114046794.1\|2989063_2989735_-\|7-carboxy-7-deazaguanine-synthase-QueE	unknown	unknown	gnl\|CDD\|275126

Protein	Function_ID	Function_description	E-value
NZ_CP046280.1\|WP_114046795.1\|2987172_2987970_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|224158	COG1237, COG1237, Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only].	2.1544e-101
NZ_CP046280.1\|WP_156017218.1\|2982773_2984486_-\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	gnl\|CDD\|237402	PRK13504, PRK13504, NADPH-dependent assimilatory sulfite reductase hemoprotein subunit.	0
NZ_CP046280.1\|WP_001145535.1\|2980922_2981876_+\|SPI-1-type-III-secretion-system-effector-SopD	gnl\|CDD\|185277	PRK15379, PRK15379, type III secretion system effector SopD.	0
NZ_CP046280.1\|WP_000036734.1\|2989870_2991169_-\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NZ_CP046280.1\|WP_114053080.1\|2974238_2974844_-\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	5.00969e-144
NZ_CP046280.1\|WP_000741649.1\|2972633_2973344_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	2.24126e-119
NZ_CP046280.1\|WP_023214376.1\|2974830_2976270_-\|sulfate-adenylyltransferase-subunit-CysN	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
NZ_CP046280.1\|WP_023136478.1\|2981963_2982698_-\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	8.84882e-138
NZ_CP046280.1\|WP_000134248.1\|2971108_2972158_-\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0
NZ_CP046280.1\|WP_000108313.1\|2986720_2987083_+\|6-carboxytetrahydropterin-synthase-QueD	gnl\|CDD\|238264	cd00470, PTPS, 6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a carrier-mediated active transport system. Most microbes and plants lack this system and must synthesize folates de novo from guanosine triphosphate. One enzyme from this pathway is PTPS which catalyzes the conversion of dihydroneopterin triphosphate to 6-pyruvoyl tetrahydropterin. The functional enzyme is a hexamer of identical subunits.	2.78454e-58
NZ_CP046280.1\|WP_000210864.1\|2991251_2992889_-\|CTP-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NZ_CP046280.1\|WP_001219244.1\|2972154_2972634_-\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	1.27909e-104
NZ_CP046280.1\|WP_156017221.1\|2984485_2986285_-\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	gnl\|CDD\|182862	PRK10953, cysJ, NADPH-dependent assimilatory sulfite reductase flavoprotein subunit.	0
NZ_CP046280.1\|WP_000372384.1\|2976279_2977188_-\|sulfate-adenylyltransferase-subunit-CysD	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
NZ_CP046280.1\|WP_000517480.1\|2973362_2973674_-\|cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	1.08865e-64
NZ_CP046280.1\|WP_156017223.1\|2993116_2993917_-\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	1.05007e-158
NZ_CP046280.1\|WP_138019900.1\|2973864_2974221_-\|DUF3561-family-protein	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	1.68584e-48
NZ_CP046280.1\|WP_023212181.1\|2977438_2978485_+\|aminopeptidase	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
NZ_CP046280.1\|WP_001221538.1\|2970366_2971128_-\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.7078e-146
NZ_CP046280.1\|WP_114046794.1\|2989063_2989735_-\|7-carboxy-7-deazaguanine-synthase-QueE	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	5.20489e-153

>NZ_CP046280.1|WP_023212181.1|2977438_2978485_+|aminopeptidase
MFSATRRFAVILALGVGFILPAQAASPAPGEIANTQARHIATFFPGRMTGSPAEMLSADYLRQQFTQMGYQSDIRTFNSRFIYTTKDNRKNWHNVTGSTVIAAHEGRVPQQIIIMAHLDTYAPQSDADVDANLGGLTLQGMDDNAAGLGVMLELAARLKDIPTHYGIRFIATSGEEEGKLGAENLLKRMSDAEKKNTLLVINLDNLIVGDKLYFNSGKNTPEAVRTLTRDRALAIARRYGIAANTNPGRNPSYPKGTGCCNDAEVFDKAGISVLSVEATNWNLGKKDGYQQRVKNASFPNGNSWHDVRLDNQQHIDKALPGRIERRSRDVVRIMLPLVKELAKAEKTS
>NZ_CP046280.1|WP_000372384.1|2976279_2977188_-|sulfate-adenylyltransferase-subunit-CysD
MDQKRLTHLRQLEAESIHIIREVAAEFANPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYAFRDRTANAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWRNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMVDDDRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESHAQTLPEIIEEMLVSTTSERQGRMIDRDQAGSMELKKRQGYF
>NZ_CP046280.1|WP_023214376.1|2974830_2976270_-|sulfate-adenylyltransferase-subunit-CysN
MNTILAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTLQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCDLAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYREETFARIREDYLTFAEQLPGDLDIRFVPLSALEGDNVAAQSANMRWYSGPTLLEVLETVDIQRAVDRQPMRFPVQYVNRPNLDFRGYAGTLASGSVKVGERIKVLPSGVESSVARIVTFDGDKEEACAGEAITLVLNDDIDISRGDLLLAANETLAPARHAAIDVVWMAEQPLAPGQSYDVKLAGKKTRARIEAIRYQIDINNLTQRDVESLPLNGIGLVEMTFDEPLALDIYQQNPVTGGLIFIDRLSNVTVGAGMVRELNERGATPPVEYSAFELELNALVRRHFPHWDARDLLGDKHGAA
>NZ_CP046280.1|WP_114053080.1|2974238_2974844_-|adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVAAREQLHGHRGVVLWFTGLSGSGKSTVAGALEEALHQRGVSTYLLDGDNVRHGLCRDLGFSDADRQENIRRVGEVAGLMADAGLIVLTAFISPHRAERQLVKECVGHDRFIEIYVNTPLAICEQRDPKGLYKKARAGELRNFTGIDAIYEAPDSPLVHLNGEQLVTNLVSQLLDLLRRRDIIRS
>NZ_CP046280.1|WP_138019900.1|2973864_2974221_-|DUF3561-family-protein
MPGMVKVTGFNMRNSHNITFTRSDAFMVDDDATGAFPGAVVGFVSWLLALGIPFLLYGPNTLFFFLYTWPFFLALMPVSVIIGIALHLLVKGKILFSIMFTLLAVGALFGALFIWLLG
>NZ_CP046280.1|WP_000517480.1|2973362_2973674_-|cell-division-protein-FtsB
MGKLTLLLLALLVWLQYSLWFGKNGIHDYSRVNDDVVAQQATNAKLKARNDQLFAEIDDLNGGQEAIEERARNELSMTKPGETFYRLVPDASKRAATAGQTHR
>NZ_CP046280.1|WP_000741649.1|2972633_2973344_-|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MAATLLDVCAVVPAAGFGRRMQTECPKQYLSIGNKTILEHSVHALLAHPRVTRVVIAISPGDHRFAQLPLANHPQITVVDGGNERADSVLAGLQAVAKAQWVLVHDAARPCLHQDDLARLLAISENSRVGGILASPVRDTMKRGEPGKNAIAHTVERADLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPALVEGRADNIKVTRPEDLALAEFYLTRTIHQEKA
>NZ_CP046280.1|WP_001219244.1|2972154_2972634_-|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLMKAAK
>NZ_CP046280.1|WP_000134248.1|2971108_2972158_-|tRNA-pseudouridine(13)-synthase-TruD
MTEFDNLTWLHGKPQGSGLLKANPEDFVVVEDLGFTPDGEGEHILLRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDFSAFQLEGCKVLEYARHKRKLRLGALKGNAFTLVLREISDRRDVETRLQAIRDGGVPNYFGAQRFGIGGSNVQGALRWAQSNAPVRDRNKRSFWLSAARSALFNQIVHQRLKKPDFNQVVDGDALQLAGRGSWFVATSEELPELQRRVDEKELMITASLPGSGEWGTQRAALAFEQDAIAQETVLQSLLLREKVEASRRAMLLYPQQLSWNWWDDVTVELRFWLPAGSFATSVVRELINTMGDYAHIAE
>NZ_CP046280.1|WP_001221538.1|2970366_2971128_-|5'/3'-nucleotidase-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFDNGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLNGYQHYDTAAAVTCALLRGLSREPLRTGRILNVNVPDLPLAQVKGIRVTRCGSRHPADKVIPQEDPRGNTLYWIGPPGDKYDAGPDTDFAAVDEGYVSVTPLHVDLTAHSAHDVVSDWLDSVGVGTQW
>NZ_CP046280.1|WP_001145535.1|2980922_2981876_+|SPI-1-type-III-secretion-system-effector-SopD
MPVTLSFGNHQNYTLNESRLAHLLSADKEKAIHMGGWDKVQDHFRAEKKDHALEVLHSIIHGQGRGEPGEMEVNVEDINKIYAFKRLQHLACPAHQDLFTIKLDASQTQFLLMVGDTVISQSNIKDILNISDDAVIESMSREERQLFLQICEVIGAKMTWHPELLQESISTLRKEVTGNAQIKTAVYEMMRPAEAPDHPLVEWQDLLTADEKSMLACINAGNFEPTTQFCKIGYQEVQGEVAFSMMHPCISYLLHSYSPFAEFKPTNSGFLKKLNQDYNDYHAKKMFIDVILEKLYLTHERSLHIGKDGCSRNILLT
>NZ_CP046280.1|WP_023136478.1|2981963_2982698_-|phosphoadenosine-phosphosulfate-reductase
MSQLDLNALNELPKVDRVLALAETNAQLETLTAEERVVWALENLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYQFIDELTDKLKLNLKVYRAGESPAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELKAQTWFAGLRREQSGSRAHLPVLAIQRGVFKVLPIIDWDNRTVYQYLQKHGLKYHPLWDQGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
>NZ_CP046280.1|WP_156017218.1|2982773_2984486_-|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit
MSEKHPGPLVVEGKLSDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAAQKLEPRHAMLLRCRLPGGVITTTQWQAIDKFAADNTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGFLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGLETFKAEVERRAGITFEPIRPYEFTGRGDRIGWVKGIDNNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHQGEFRITANQNLIIASVPESQKAKIEKLARDHGLMNAVSAQRENSMACVSFPTCPLAMAEAERFLPSFTDKVEAILEKHGIPDEHIVMRVTGCPNGCGRAMLAEIGLVGKAPGRYNLHLGGNRIGTRIPRMYQENITEPDILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDFWE
>NZ_CP046280.1|WP_156017221.1|2984485_2986285_-|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit
MTTPAPLTGLLPLNPEQLARLQAATTDLTPEQLAWVSGYFWGVLNPRSGAVAVTPVPERKMLGVTLISASQTGNARRVAEALRDDLLAANLNVTLVNAGDYKFKQIASEKLLVIVTSTQGEGEPPEEAVALHKFLFSKKAPKLTDTAFAVFSLGDTSYEFFCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDVLKSRAPVAAPSQSVATGAVNDIHTSPYTKDAPLTATLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDALGVWYQNDPALVKELVELLWLKGDEPVTVDSKTLPLAEALEWHFELTVNTANIVENYATLTRSESLLPLVGDKAQLQHYAATTPIVDMVRFSPAQLDAQALIDLLRPLTPRLYSIASSQAETENEVHVTVGVVRYDIEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPANPETPVIMIGPGTGIAPFRAFMQQRAADGAEGKNWLFFGNPHFTEDFLYQVEWQRYVKEGLLSRIDLAWSRDQKEKIYVQDKLREQGAELWRWINDGAHIYVCGDARRMAADVEKALLEVIAEFGGMDLESADEYLSELRVERRYQRDVY
>NZ_CP046280.1|WP_000108313.1|2986720_2987083_+|6-carboxytetrahydropterin-synthase-QueD
MSTTLYKDFTFEAAHRLPHVPEGHKCGRLHGHSFMVRLEITGEVDPHTGWIMDFADLKAAFKPTYDRLDHYYLNDIPGLSNPTSEVLAKWIWDQVKPVVPLLSAVMVKETCTAGCVYRGE
>NZ_CP046280.1|WP_114046795.1|2987172_2987970_-|MBL-fold-metallo-hydrolase
MALRIRVLLENHKGAGADKSLKARPGLSLLVEDESTSILFDTGPDGSFMQNASAMGIDLSDVSAVVLSHGHYDHCGGVPWLPDNSRIICHPDIARERYAAMTFLGITRKIKKLSCEVDYSRYRMMYTRDPLPIGENFIWSGEISVVAPEAYGIFGGHDAEPDSILDEGVLIYQSAKGLVIITGCGHRGIANIVRHCQNITGIKQIYALIGGFHLRCASPFTLWRVRRFLQEQKPEKLCGCHCTGAWGRLWLPEITAPATGDVLRF
>NZ_CP046280.1|WP_114046794.1|2989063_2989735_-|7-carboxy-7-deazaguanine-synthase-QueE
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWDKLSDREVSLFSILAKTKESDKWGAASSEDLLAVINRQGYTARHVVITGGEPCIHDLMSLTDLLEKSGFSCQIETSGTHEVCCTPNTWVTVSPKVNMRGGYDVLSQALERANEIKHPVGRVRDIEALDELLATLSDDKPRVIALQPISQKEDATRLCIETCIARNWRLSMQTHKYLNIA
>NZ_CP046280.1|WP_000036734.1|2989870_2991169_-|phosphopyruvate-hydratase
MSKIVKVIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVGAVNGPIAQAILGKDAKDQAGIDKIMIDLDGTENKSNFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKGKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>NZ_CP046280.1|WP_000210864.1|2991251_2992889_-|CTP-synthase-(glutamine-hydrolyzing)
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQLAVDIGREHALFMHLTLVPYLAAAGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISMKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIYEEANPAGEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVTVNIKLIDSQDVETRGVEILKDLDAILIPGGFGYRGVEGKIATARYARENNIPYLGICLGMQVALIEFARNVAGMDNANSTEFVPDCKYPVVALITEWRDEDGNVEVRSEKSDLGGTMRLGAQQCQLSDDSLVRQLYGASTIVERHRHRYEVNNMLLKQIEAAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEHQKRQAK
>NZ_CP046280.1|WP_156017223.1|2993116_2993917_-|nucleoside-triphosphate-pyrophosphohydrolase
MTTNHQIDRLLTLMQRLRDPENGCPWDKEQTFASIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKMERRHPHVFGELSAGNSEEALVRWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCSNVGFDWTTLGPVVDKVYEEIDEVMFEARQAVVDQAKLEEEMGDLLFATVNMARHLGTKAELALQKANDKFERRFREVERIVAARGLEMTGVDLETMEEVWQEVKRQEIDL

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Crispr_ID: NZ_CP046280_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP046280_2

2988068-2988767

Orphan

I-E

Consensus_repeat	Method
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CRISPRCasFinder
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CRT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	PILER-CR

11 spacers

The CRISPR arrays of NZ_CP046280_2

>merge|NZ_CP046280|2|2988068-2988767|CRISPRCasFinder,CRT,PILER-CR
ACGGCTATCCCCGCTGGCGCGGGGAACACGTTACCGTTGGCGTAACGCTGAATTGTTGGTACGGTTTATCCCCGCTGACGCGGGGAACACACGGCAACGGATGCGACCGCCAGCGCGATCCCCGGTTTATCCCCGCTGGCGCGGGGAACACGTATCCTGCCCGGGCACTGTTGGTTCGACGCCCGGTTTATCCCCGCTGGCGCGGGGAACACCAACATCCAGTAAGTCTTGTTTGTTTCTGATTCGGTTTATCCCCGCTGGCGCGGGGAACACGCTCATCCTGTCGGCGTTTGCCATGTCTAAAACGGTTTATCCCCGCTGGCGCGGGGAACACCTGGTCCTGTTCGCACTGATAAACGCCGTCGCCGGTTTATCCCCGCTGGCGCGGGGAACACCCCGGAATATATCCCTGCTGAGAATGAAGGCGCGGTTTATCCCCGCTGGCACGGGGAACACTTTGGTGAAATTGTTCTGGCTGTCGATGTAGCCGGTTTATCCCCGCTGGCGCGGGGAACACGGCCCGTCCTTTTGCATGGCTGCGACAACGGGCGGTTTATCCCCGCTGGCGCGGGGAACACGACGGACTGGAAAAACTCATCATTTCTGAAGACGGTTTATCCCCGCTGGCGCGGGGAACACTTGCCCGGTAGTTTTTGCTGTCGACCTGTCCGCGGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP046280|2|2|2988068-2988767|CRISPRCasFinder
ACGGCTATCCCCGCTGGCGCGGGGAACAC	GTTACCGTTGGCGTAACGCTGAATTGTTGGTA
CGGTTTATCCCCGCTGACGCGGGGAACAC	ACGGCAACGGATGCGACCGCCAGCGCGATCCC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTATCCTGCCCGGGCACTGTTGGTTCGACGCC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CAACATCCAGTAAGTCTTGTTTGTTTCTGATT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCTCATCCTGTCGGCGTTTGCCATGTCTAAAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CTGGTCCTGTTCGCACTGATAAACGCCGTCGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CCCGGAATATATCCCTGCTGAGAATGAAGGCG
CGGTTTATCCCCGCTGGCACGGGGAACAC	TTTGGTGAAATTGTTCTGGCTGTCGATGTAGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GGCCCGTCCTTTTGCATGGCTGCGACAACGGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GACGGACTGGAAAAACTCATCATTTCTGAAGA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TTGCCCGGTAGTTTTTGCTGTCGACCTGTCCG
CGGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP046280|2|2|2988068-2988767|CRT
ACGGCTATCCCCGCTGGCGCGGGGAACAC	GTTACCGTTGGCGTAACGCTGAATTGTTGGTA
CGGTTTATCCCCGCTGACGCGGGGAACAC	ACGGCAACGGATGCGACCGCCAGCGCGATCCC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTATCCTGCCCGGGCACTGTTGGTTCGACGCC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CAACATCCAGTAAGTCTTGTTTGTTTCTGATT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCTCATCCTGTCGGCGTTTGCCATGTCTAAAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CTGGTCCTGTTCGCACTGATAAACGCCGTCGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CCCGGAATATATCCCTGCTGAGAATGAAGGCG
CGGTTTATCCCCGCTGGCACGGGGAACAC	TTTGGTGAAATTGTTCTGGCTGTCGATGTAGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GGCCCGTCCTTTTGCATGGCTGCGACAACGGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GACGGACTGGAAAAACTCATCATTTCTGAAGA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TTGCCCGGTAGTTTTTGCTGTCGACCTGTCCG
CGGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP046280|2|2|2988129-2988767|PILER-CR
CGGTTTATCCCCGCTGACGCGGGGAACAC	ACGGCAACGGATGCGACCGCCAGCGCGATCCC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTATCCTGCCCGGGCACTGTTGGTTCGACGCC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CAACATCCAGTAAGTCTTGTTTGTTTCTGATT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCTCATCCTGTCGGCGTTTGCCATGTCTAAAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CTGGTCCTGTTCGCACTGATAAACGCCGTCGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CCCGGAATATATCCCTGCTGAGAATGAAGGCG
CGGTTTATCCCCGCTGGCACGGGGAACAC	TTTGGTGAAATTGTTCTGGCTGTCGATGTAGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GGCCCGTCCTTTTGCATGGCTGCGACAACGGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GACGGACTGGAAAAACTCATCATTTCTGAAGA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TTGCCCGGTAGTTTTTGCTGTCGACCTGTCCG
CGGTTTATCCCCGCTGGCGCGGGGAACAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046280.1\|WP_114046795.1\|2987172_2987970_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|224158
NZ_CP046280.1\|WP_000706486.1\|3001828_3002971_-\|glycerate-kinase	unknown	unknown	gnl\|CDD\|224840
NZ_CP046280.1\|WP_000210864.1\|2991251_2992889_-\|CTP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|235437
NZ_CP046280.1\|WP_001145535.1\|2980922_2981876_+\|SPI-1-type-III-secretion-system-effector-SopD	unknown	unknown	gnl\|CDD\|185277
NZ_CP046280.1\|WP_000036734.1\|2989870_2991169_-\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NZ_CP046280.1\|WP_114053080.1\|2974238_2974844_-\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
NZ_CP046280.1\|WP_114053077.1\|2994686_2994983_-\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	unknown	unknown	gnl\|CDD\|226194
NZ_CP046280.1\|WP_023214376.1\|2974830_2976270_-\|sulfate-adenylyltransferase-subunit-CysN	unknown	unknown	gnl\|CDD\|235349
NZ_CP046280.1\|WP_023136478.1\|2981963_2982698_-\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NZ_CP046280.1\|WP_015406304.1\|2997675_2998971_-\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl\|CDD\|237291
NZ_CP046280.1\|WP_000108313.1\|2986720_2987083_+\|6-carboxytetrahydropterin-synthase-QueD	unknown	unknown	gnl\|CDD\|238264
NZ_CP046280.1\|WP_000186399.1\|2999028_3001785_+\|two-component-sensor-histidine-kinase-BarA	unknown	unknown	gnl\|CDD\|236848
NZ_CP046280.1\|WP_000372384.1\|2976279_2977188_-\|sulfate-adenylyltransferase-subunit-CysD	unknown	unknown	gnl\|CDD\|235375
NZ_CP046280.1\|WP_156017218.1\|2982773_2984486_-\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	unknown	unknown	gnl\|CDD\|237402
NZ_CP046280.1\|WP_156017223.1\|2993116_2993917_-\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569
NZ_CP046280.1\|WP_156017221.1\|2984485_2986285_-\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	unknown	unknown	gnl\|CDD\|182862
NZ_CP046280.1\|WP_156017226.1\|2994948_2995305_-\|type-II-toxin-antitoxin-system-ParD-family-antitoxin	unknown	unknown	gnl\|CDD\|226136
NZ_CP046280.1\|WP_000226841.1\|2995389_2997624_-\|GTP-diphosphokinase	unknown	unknown	gnl\|CDD\|182797
NZ_CP046280.1\|WP_023212181.1\|2977438_2978485_+\|aminopeptidase	unknown	unknown	gnl\|CDD\|182299
NZ_CP046280.1\|WP_114046794.1\|2989063_2989735_-\|7-carboxy-7-deazaguanine-synthase-QueE	unknown	unknown	gnl\|CDD\|275126

Protein	Function_ID	Function_description	E-value
NZ_CP046280.1\|WP_114046795.1\|2987172_2987970_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|224158	COG1237, COG1237, Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only].	2.1544e-101
NZ_CP046280.1\|WP_000706486.1\|3001828_3002971_-\|glycerate-kinase	gnl\|CDD\|224840	COG1929, COG1929, Glycerate kinase [Carbohydrate transport and metabolism].	0
NZ_CP046280.1\|WP_000210864.1\|2991251_2992889_-\|CTP-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NZ_CP046280.1\|WP_001145535.1\|2980922_2981876_+\|SPI-1-type-III-secretion-system-effector-SopD	gnl\|CDD\|185277	PRK15379, PRK15379, type III secretion system effector SopD.	0
NZ_CP046280.1\|WP_000036734.1\|2989870_2991169_-\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NZ_CP046280.1\|WP_114053080.1\|2974238_2974844_-\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	5.00969e-144
NZ_CP046280.1\|WP_114053077.1\|2994686_2994983_-\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	gnl\|CDD\|226194	COG3668, ParE, Plasmid stabilization system protein [General function prediction only].	3.19302e-11
NZ_CP046280.1\|WP_023214376.1\|2974830_2976270_-\|sulfate-adenylyltransferase-subunit-CysN	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
NZ_CP046280.1\|WP_023136478.1\|2981963_2982698_-\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	8.84882e-138
NZ_CP046280.1\|WP_015406304.1\|2997675_2998971_-\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl\|CDD\|237291	PRK13168, rumA, 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD.	0
NZ_CP046280.1\|WP_000108313.1\|2986720_2987083_+\|6-carboxytetrahydropterin-synthase-QueD	gnl\|CDD\|238264	cd00470, PTPS, 6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a carrier-mediated active transport system. Most microbes and plants lack this system and must synthesize folates de novo from guanosine triphosphate. One enzyme from this pathway is PTPS which catalyzes the conversion of dihydroneopterin triphosphate to 6-pyruvoyl tetrahydropterin. The functional enzyme is a hexamer of identical subunits.	2.78454e-58
NZ_CP046280.1\|WP_000186399.1\|2999028_3001785_+\|two-component-sensor-histidine-kinase-BarA	gnl\|CDD\|236848	PRK11107, PRK11107, hybrid sensory histidine kinase BarA; Provisional.	0
NZ_CP046280.1\|WP_000372384.1\|2976279_2977188_-\|sulfate-adenylyltransferase-subunit-CysD	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
NZ_CP046280.1\|WP_156017218.1\|2982773_2984486_-\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	gnl\|CDD\|237402	PRK13504, PRK13504, NADPH-dependent assimilatory sulfite reductase hemoprotein subunit.	0
NZ_CP046280.1\|WP_156017223.1\|2993116_2993917_-\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	1.05007e-158
NZ_CP046280.1\|WP_156017221.1\|2984485_2986285_-\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	gnl\|CDD\|182862	PRK10953, cysJ, NADPH-dependent assimilatory sulfite reductase flavoprotein subunit.	0
NZ_CP046280.1\|WP_156017226.1\|2994948_2995305_-\|type-II-toxin-antitoxin-system-ParD-family-antitoxin	gnl\|CDD\|226136	COG3609, COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain [Transcription].	9.27291e-20
NZ_CP046280.1\|WP_000226841.1\|2995389_2997624_-\|GTP-diphosphokinase	gnl\|CDD\|182797	PRK10872, relA, (p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional.	0
NZ_CP046280.1\|WP_023212181.1\|2977438_2978485_+\|aminopeptidase	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
NZ_CP046280.1\|WP_114046794.1\|2989063_2989735_-\|7-carboxy-7-deazaguanine-synthase-QueE	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	5.20489e-153

>NZ_CP046280.1|WP_114046795.1|2987172_2987970_-|MBL-fold-metallo-hydrolase
MALRIRVLLENHKGAGADKSLKARPGLSLLVEDESTSILFDTGPDGSFMQNASAMGIDLSDVSAVVLSHGHYDHCGGVPWLPDNSRIICHPDIARERYAAMTFLGITRKIKKLSCEVDYSRYRMMYTRDPLPIGENFIWSGEISVVAPEAYGIFGGHDAEPDSILDEGVLIYQSAKGLVIITGCGHRGIANIVRHCQNITGIKQIYALIGGFHLRCASPFTLWRVRRFLQEQKPEKLCGCHCTGAWGRLWLPEITAPATGDVLRF
>NZ_CP046280.1|WP_000108313.1|2986720_2987083_+|6-carboxytetrahydropterin-synthase-QueD
MSTTLYKDFTFEAAHRLPHVPEGHKCGRLHGHSFMVRLEITGEVDPHTGWIMDFADLKAAFKPTYDRLDHYYLNDIPGLSNPTSEVLAKWIWDQVKPVVPLLSAVMVKETCTAGCVYRGE
>NZ_CP046280.1|WP_156017221.1|2984485_2986285_-|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit
MTTPAPLTGLLPLNPEQLARLQAATTDLTPEQLAWVSGYFWGVLNPRSGAVAVTPVPERKMLGVTLISASQTGNARRVAEALRDDLLAANLNVTLVNAGDYKFKQIASEKLLVIVTSTQGEGEPPEEAVALHKFLFSKKAPKLTDTAFAVFSLGDTSYEFFCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDVLKSRAPVAAPSQSVATGAVNDIHTSPYTKDAPLTATLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDALGVWYQNDPALVKELVELLWLKGDEPVTVDSKTLPLAEALEWHFELTVNTANIVENYATLTRSESLLPLVGDKAQLQHYAATTPIVDMVRFSPAQLDAQALIDLLRPLTPRLYSIASSQAETENEVHVTVGVVRYDIEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPANPETPVIMIGPGTGIAPFRAFMQQRAADGAEGKNWLFFGNPHFTEDFLYQVEWQRYVKEGLLSRIDLAWSRDQKEKIYVQDKLREQGAELWRWINDGAHIYVCGDARRMAADVEKALLEVIAEFGGMDLESADEYLSELRVERRYQRDVY
>NZ_CP046280.1|WP_156017218.1|2982773_2984486_-|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit
MSEKHPGPLVVEGKLSDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAAQKLEPRHAMLLRCRLPGGVITTTQWQAIDKFAADNTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGFLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGLETFKAEVERRAGITFEPIRPYEFTGRGDRIGWVKGIDNNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHQGEFRITANQNLIIASVPESQKAKIEKLARDHGLMNAVSAQRENSMACVSFPTCPLAMAEAERFLPSFTDKVEAILEKHGIPDEHIVMRVTGCPNGCGRAMLAEIGLVGKAPGRYNLHLGGNRIGTRIPRMYQENITEPDILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDFWE
>NZ_CP046280.1|WP_023136478.1|2981963_2982698_-|phosphoadenosine-phosphosulfate-reductase
MSQLDLNALNELPKVDRVLALAETNAQLETLTAEERVVWALENLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYQFIDELTDKLKLNLKVYRAGESPAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELKAQTWFAGLRREQSGSRAHLPVLAIQRGVFKVLPIIDWDNRTVYQYLQKHGLKYHPLWDQGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
>NZ_CP046280.1|WP_001145535.1|2980922_2981876_+|SPI-1-type-III-secretion-system-effector-SopD
MPVTLSFGNHQNYTLNESRLAHLLSADKEKAIHMGGWDKVQDHFRAEKKDHALEVLHSIIHGQGRGEPGEMEVNVEDINKIYAFKRLQHLACPAHQDLFTIKLDASQTQFLLMVGDTVISQSNIKDILNISDDAVIESMSREERQLFLQICEVIGAKMTWHPELLQESISTLRKEVTGNAQIKTAVYEMMRPAEAPDHPLVEWQDLLTADEKSMLACINAGNFEPTTQFCKIGYQEVQGEVAFSMMHPCISYLLHSYSPFAEFKPTNSGFLKKLNQDYNDYHAKKMFIDVILEKLYLTHERSLHIGKDGCSRNILLT
>NZ_CP046280.1|WP_023212181.1|2977438_2978485_+|aminopeptidase
MFSATRRFAVILALGVGFILPAQAASPAPGEIANTQARHIATFFPGRMTGSPAEMLSADYLRQQFTQMGYQSDIRTFNSRFIYTTKDNRKNWHNVTGSTVIAAHEGRVPQQIIIMAHLDTYAPQSDADVDANLGGLTLQGMDDNAAGLGVMLELAARLKDIPTHYGIRFIATSGEEEGKLGAENLLKRMSDAEKKNTLLVINLDNLIVGDKLYFNSGKNTPEAVRTLTRDRALAIARRYGIAANTNPGRNPSYPKGTGCCNDAEVFDKAGISVLSVEATNWNLGKKDGYQQRVKNASFPNGNSWHDVRLDNQQHIDKALPGRIERRSRDVVRIMLPLVKELAKAEKTS
>NZ_CP046280.1|WP_000372384.1|2976279_2977188_-|sulfate-adenylyltransferase-subunit-CysD
MDQKRLTHLRQLEAESIHIIREVAAEFANPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYAFRDRTANAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWRNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMVDDDRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESHAQTLPEIIEEMLVSTTSERQGRMIDRDQAGSMELKKRQGYF
>NZ_CP046280.1|WP_023214376.1|2974830_2976270_-|sulfate-adenylyltransferase-subunit-CysN
MNTILAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTLQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCDLAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYREETFARIREDYLTFAEQLPGDLDIRFVPLSALEGDNVAAQSANMRWYSGPTLLEVLETVDIQRAVDRQPMRFPVQYVNRPNLDFRGYAGTLASGSVKVGERIKVLPSGVESSVARIVTFDGDKEEACAGEAITLVLNDDIDISRGDLLLAANETLAPARHAAIDVVWMAEQPLAPGQSYDVKLAGKKTRARIEAIRYQIDINNLTQRDVESLPLNGIGLVEMTFDEPLALDIYQQNPVTGGLIFIDRLSNVTVGAGMVRELNERGATPPVEYSAFELELNALVRRHFPHWDARDLLGDKHGAA
>NZ_CP046280.1|WP_114053080.1|2974238_2974844_-|adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVAAREQLHGHRGVVLWFTGLSGSGKSTVAGALEEALHQRGVSTYLLDGDNVRHGLCRDLGFSDADRQENIRRVGEVAGLMADAGLIVLTAFISPHRAERQLVKECVGHDRFIEIYVNTPLAICEQRDPKGLYKKARAGELRNFTGIDAIYEAPDSPLVHLNGEQLVTNLVSQLLDLLRRRDIIRS
>NZ_CP046280.1|WP_114046794.1|2989063_2989735_-|7-carboxy-7-deazaguanine-synthase-QueE
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWDKLSDREVSLFSILAKTKESDKWGAASSEDLLAVINRQGYTARHVVITGGEPCIHDLMSLTDLLEKSGFSCQIETSGTHEVCCTPNTWVTVSPKVNMRGGYDVLSQALERANEIKHPVGRVRDIEALDELLATLSDDKPRVIALQPISQKEDATRLCIETCIARNWRLSMQTHKYLNIA
>NZ_CP046280.1|WP_000036734.1|2989870_2991169_-|phosphopyruvate-hydratase
MSKIVKVIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVGAVNGPIAQAILGKDAKDQAGIDKIMIDLDGTENKSNFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKGKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>NZ_CP046280.1|WP_000210864.1|2991251_2992889_-|CTP-synthase-(glutamine-hydrolyzing)
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQLAVDIGREHALFMHLTLVPYLAAAGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISMKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIYEEANPAGEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVTVNIKLIDSQDVETRGVEILKDLDAILIPGGFGYRGVEGKIATARYARENNIPYLGICLGMQVALIEFARNVAGMDNANSTEFVPDCKYPVVALITEWRDEDGNVEVRSEKSDLGGTMRLGAQQCQLSDDSLVRQLYGASTIVERHRHRYEVNNMLLKQIEAAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEHQKRQAK
>NZ_CP046280.1|WP_156017223.1|2993116_2993917_-|nucleoside-triphosphate-pyrophosphohydrolase
MTTNHQIDRLLTLMQRLRDPENGCPWDKEQTFASIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKMERRHPHVFGELSAGNSEEALVRWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCSNVGFDWTTLGPVVDKVYEEIDEVMFEARQAVVDQAKLEEEMGDLLFATVNMARHLGTKAELALQKANDKFERRFREVERIVAARGLEMTGVDLETMEEVWQEVKRQEIDL
>NZ_CP046280.1|WP_114053077.1|2994686_2994983_-|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin
MITVKLTPKVSEDLENIWHYGWQHFGEIKADRYINHLSEIFSIMSANNIGTPRPELGEYIYALPFERHIIYFIQSVTEVIVIRILSQNQDAGKHVNWL
>NZ_CP046280.1|WP_156017226.1|2994948_2995305_-|type-II-toxin-antitoxin-system-ParD-family-antitoxin
MFLTYISFPVYSYVRFILTVEAVMVRTMTVDLGDELREFIESLIESGDYRTQSEVIRESLRLLREKQAESRLQALRELLAEGLNSGEPQAWEKDAFLRKVKTGMIKPDDNGKINAKGQ
>NZ_CP046280.1|WP_000226841.1|2995389_2997624_-|GTP-diphosphokinase
MVAVRSAHINKAGEFDPKKWIASLGISSQQSCERLAETWAYCLQQTQGHPDADLLLWRGVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKSIVTLIHGVRDMAAIRQLNATHNDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHLREVKEAPEDERVLAAKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPAEYKRIAKLLHERRLDREHYIEEFVGHLRAEMKNEGVQAEVYGRPKHIYSIWRKMQKKHLAFDELFDVRAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTVEIQIRTKQMHEDAELGVAAHWKYKEGAASGGVRSGHEDRIAWLRKLIAWQEEMADSGEMLDEVRSQVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGDQVEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAGRQILDDELAHLGISLKEAEKHLLPRYNFNELEELLAAIGGGDIRLNQMVNFLQSQFNKPSAEEQDAAALKQLQQKTYAPQNRRKDDGRVVVEGVGNLMHHIARCCQPIPGDEIVGFITQGRGISVHRADCEQLAELRSHAPERIVEAVWGESYSAGYSLVVRVQANDRSGLLRDITTILANEKVNVLGVASRSDIKQQIATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARRLHGG
>NZ_CP046280.1|WP_015406304.1|2997675_2998971_-|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MAQFYSAKRRVTTRQIITVKVNDLDSFGQGVARHNGKALFIPGLLPEESAEVIITEDKKQFARARVSRRLNDSPERETPRCPHFGVCGGCQQQHVSIALQQRSKSAALARLMKHEVNDIIAGAPWGYRRRARLSLNCPPDKPLQMGFRKAGSSDIVNVEQCPVLAPQLAALLPRIRACLASLHGTRHLGHVELVQAGSGTLMILRHTAPLSAADKEKLERFSHSEGLSLFLAPFSEILETVSGEAPWYDSHGLRLAFSPRDFIQVNEVVNQQMVARALEWLDVRAEDRVLDLFCGMGNFTLPLATRAASVVGVEGVPALVEKGRENAIRNGLHNVTFFHENLEEDVTKQPWAKNGFDKVLLDPARAGATGVMRHIIKLKPIRIVYVSCNPATLARDSEALVNAGYEVTRLAMLDMFPHTGHLESMVLFERM
>NZ_CP046280.1|WP_000186399.1|2999028_3001785_+|two-component-sensor-histidine-kinase-BarA
MTNYSLRARMMILILAPTVLIGLLLSIFFVVHRYNDLQRQLEDAGASIIEPLAVSSEYGMNLQNRESIGQLISVLHRRHSDIVRAISVYDDHNRLFVTSNFHLDPSQMQLPAGAPFPRRLSVDRHGDIMILRTPIISESYSPDESAIADAKNTKNMLGYVALELDLKSVRLQQYKEIFISSVMMLFCIGIALIFGWRLMRDVTGPIRNMVNTVDRIRRGQLDSRVEGFMLGELDMLKNGINSMAMSLAAYHEEMQHNIDQATSDLRETLEQMEIQNVELDLAKKRAQEAARIKSEFLANMSHELRTPLNGVIGFTRLTLKTELNPTQRDHLNTIERSANNLLAIINDVLDFSKLEAGKLILESIPFPLRNTLDEVVTLLAHSSHDKGLELTLNIKNDVPDNVIGDPLRLQQVITNLVGNAIKFTESGNIDILVEKRALSNTKVQIEVQIRDTGIGIPERDQSRLFQAFRQADASISRRHGGTGLGLVITQKLVNEMGGDISFHSQPNRGSTFWFHINLDLNPNVIIDGPSTACLAGKRLAYVEPNATAAQCTLDLLSDTPVEVVYSPTFSALPLAHYDIMILSVPVTFREPLTMQHERLAKAASMTDFLLLALPCHAQINAEKLKQGGAAACLLKPLTSTRLLPALTEYCQLNHHPEPLLMDTSKITMTVMAVDDNPANLKLIGALLEDKVQHVELCDSGHQAVDRAKQMQFDLILMDIQMPDMDGIRACELIHQLPHQQQTPVIAVTAHAMAGQKEKLLSAGMNDYLAKPIEEEKLHNLLLRYKPGANVAARLMAPEPAEFIFNPNATLDWQLALRQAAGKPDLARDMLQMLIDFLPEVRNKIEEQLVGENPNGLVDLIHKLHGSCGYSGVPRMKNLCQLIEQQLRSGVHEEELEPEFLELLDEMDNVAREAKKILG
>NZ_CP046280.1|WP_000706486.1|3001828_3002971_-|glycerate-kinase
MKIVIAPDSYKESLSALEVATAIEQGFREIWPDADYLKLPLADGGEGTVEAMVEATAGRIVHVEVTGPLGHRVNAFYGLSGDARSAFIEMAAASGLEQVPPAQRDPLKTTSWGTGELIRHALDAGVEHIIIGIGGSATNDGGAGMVQALGARLRDAQGNDIVQGGIGLETLASIDISGLDKRLSACHIEVACDVTNPLTGKEGASAVFGPQKGATPEMIERLDTALTRYAHLIARDLHVDVLDLAGGGAAGGMGAALYAFCGAQLRRGIEIVTDALHLEACLADADLVITGEGRIDSQTIHGKVPIGVANIAKRYNKPVIGIAGSLTADVGVVHEHGLDAVFSVIYTICTLEDALKNASENVRMTARNVAATLKAGQQLR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP046280_1	1.6\|2978834\|32\|NZ_CP046280\|CRISPRCasFinder,CRT	2978834-2978865	32	NC_010393	Phage Gifsy-2, complete genome	30283-30314	0	1.0
NZ_CP046280_1	1.6\|2978834\|32\|NZ_CP046280\|CRISPRCasFinder,CRT	2978834-2978865	32	NC_010392	Phage Gifsy-1, complete genome	15133-15164	0	1.0
NZ_CP046280_1	1.8\|2978956\|33\|NZ_CP046280\|CRISPRCasFinder,CRT	2978956-2978988	33	JQ288021	Salmonella phage SPN3UB, complete genome	31467-31499	0	1.0
NZ_CP046280_1	1.8\|2978956\|33\|NZ_CP046280\|CRISPRCasFinder,CRT	2978956-2978988	33	NC_010393	Phage Gifsy-2, complete genome	4110-4142	0	1.0
NZ_CP046280_1	1.8\|2978956\|33\|NZ_CP046280\|CRISPRCasFinder,CRT	2978956-2978988	33	NC_010392	Phage Gifsy-1, complete genome	44259-44291	0	1.0
NZ_CP046280_1	1.14\|2978836\|32\|NZ_CP046280\|PILER-CR	2978836-2978867	32	NC_010393	Phage Gifsy-2, complete genome	30283-30314	0	1.0
NZ_CP046280_1	1.14\|2978836\|32\|NZ_CP046280\|PILER-CR	2978836-2978867	32	NC_010392	Phage Gifsy-1, complete genome	15133-15164	0	1.0
NZ_CP046280_1	1.16\|2978958\|33\|NZ_CP046280\|PILER-CR	2978958-2978990	33	JQ288021	Salmonella phage SPN3UB, complete genome	31467-31499	0	1.0
NZ_CP046280_1	1.16\|2978958\|33\|NZ_CP046280\|PILER-CR	2978958-2978990	33	NC_010393	Phage Gifsy-2, complete genome	4110-4142	0	1.0
NZ_CP046280_1	1.16\|2978958\|33\|NZ_CP046280\|PILER-CR	2978958-2978990	33	NC_010392	Phage Gifsy-1, complete genome	44259-44291	0	1.0
NZ_CP046280_1	1.1\|2978529\|32\|NZ_CP046280\|CRISPRCasFinder,CRT	2978529-2978560	32	CP053320	Salmonella enterica subsp. arizonae serovar 41:z4,z23:- strain 2016K-0011 plasmid unnamed, complete sequence	33265-33296	1	0.969
NZ_CP046280_1	1.2\|2978590\|32\|NZ_CP046280\|CRISPRCasFinder,CRT	2978590-2978621	32	CP053320	Salmonella enterica subsp. arizonae serovar 41:z4,z23:- strain 2016K-0011 plasmid unnamed, complete sequence	28847-28878	1	0.969
NZ_CP046280_1	1.8\|2978956\|33\|NZ_CP046280\|CRISPRCasFinder,CRT	2978956-2978988	33	KC139516	Salmonella phage FSL SP-016, partial genome	4587-4619	1	0.97
NZ_CP046280_1	1.9\|2978531\|32\|NZ_CP046280\|PILER-CR	2978531-2978562	32	CP053320	Salmonella enterica subsp. arizonae serovar 41:z4,z23:- strain 2016K-0011 plasmid unnamed, complete sequence	33265-33296	1	0.969
NZ_CP046280_1	1.10\|2978592\|32\|NZ_CP046280\|PILER-CR	2978592-2978623	32	CP053320	Salmonella enterica subsp. arizonae serovar 41:z4,z23:- strain 2016K-0011 plasmid unnamed, complete sequence	28847-28878	1	0.969
NZ_CP046280_1	1.16\|2978958\|33\|NZ_CP046280\|PILER-CR	2978958-2978990	33	KC139516	Salmonella phage FSL SP-016, partial genome	4587-4619	1	0.97
NZ_CP046280_2	2.8\|2988524\|32\|NZ_CP046280\|CRISPRCasFinder,CRT,PILER-CR	2988524-2988555	32	NZ_CP044178	Salmonella enterica subsp. enterica serovar Concord strain AR-0407 plasmid pAR-0407-1	30823-30854	2	0.938
NZ_CP046280_2	2.2\|2988158\|32\|NZ_CP046280\|CRISPRCasFinder,CRT,PILER-CR	2988158-2988189	32	NZ_CP024424	Paracoccus yeei strain TT13 plasmid pTT13-2, complete sequence	112052-112083	5	0.844
NZ_CP046280_2	2.2\|2988158\|32\|NZ_CP046280\|CRISPRCasFinder,CRT,PILER-CR	2988158-2988189	32	NZ_CP020440	Paracoccus yeei strain FDAARGOS_252 plasmid unnamed2, complete sequence	224971-225002	5	0.844
NZ_CP046280_2	2.2\|2988158\|32\|NZ_CP046280\|CRISPRCasFinder,CRT,PILER-CR	2988158-2988189	32	NZ_CP044082	Paracoccus yeei strain FDAARGOS_643 plasmid unnamed4, complete sequence	90792-90823	5	0.844
NZ_CP046280_2	2.2\|2988158\|32\|NZ_CP046280\|CRISPRCasFinder,CRT,PILER-CR	2988158-2988189	32	NZ_CP031080	Paracoccus yeei strain CCUG 32053 plasmid pYEE2, complete sequence	271400-271431	6	0.812
NZ_CP046280_1	1.3\|2978651\|32\|NZ_CP046280\|CRISPRCasFinder,CRT	2978651-2978682	32	NC_004669	Enterococcus faecalis V583 plasmid pTEF1, complete sequence	20485-20516	7	0.781
NZ_CP046280_1	1.3\|2978651\|32\|NZ_CP046280\|CRISPRCasFinder,CRT	2978651-2978682	32	NZ_CP031029	Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-2, complete sequence	50854-50885	7	0.781
NZ_CP046280_1	1.3\|2978651\|32\|NZ_CP046280\|CRISPRCasFinder,CRT	2978651-2978682	32	NZ_CP019513	Enterococcus faecalis strain CLB21560 plasmid pA, complete sequence	59304-59335	7	0.781
NZ_CP046280_1	1.3\|2978651\|32\|NZ_CP046280\|CRISPRCasFinder,CRT	2978651-2978682	32	NC_002630	Enterococcus faecalis plasmid pAM373, complete sequence	15378-15409	7	0.781
NZ_CP046280_1	1.4\|2978712\|32\|NZ_CP046280\|CRISPRCasFinder,CRT	2978712-2978743	32	NC_048066	Vibrio phage 1.202.O._10N.222.45.E8, partial genome	25336-25367	7	0.781
NZ_CP046280_1	1.11\|2978653\|32\|NZ_CP046280\|PILER-CR	2978653-2978684	32	NC_004669	Enterococcus faecalis V583 plasmid pTEF1, complete sequence	20485-20516	7	0.781
NZ_CP046280_1	1.11\|2978653\|32\|NZ_CP046280\|PILER-CR	2978653-2978684	32	NZ_CP031029	Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-2, complete sequence	50854-50885	7	0.781
NZ_CP046280_1	1.11\|2978653\|32\|NZ_CP046280\|PILER-CR	2978653-2978684	32	NZ_CP019513	Enterococcus faecalis strain CLB21560 plasmid pA, complete sequence	59304-59335	7	0.781
NZ_CP046280_1	1.11\|2978653\|32\|NZ_CP046280\|PILER-CR	2978653-2978684	32	NC_002630	Enterococcus faecalis plasmid pAM373, complete sequence	15378-15409	7	0.781
NZ_CP046280_1	1.12\|2978714\|32\|NZ_CP046280\|PILER-CR	2978714-2978745	32	NC_048066	Vibrio phage 1.202.O._10N.222.45.E8, partial genome	25336-25367	7	0.781
NZ_CP046280_2	2.2\|2988158\|32\|NZ_CP046280\|CRISPRCasFinder,CRT,PILER-CR	2988158-2988189	32	NC_009621	Sinorhizobium medicae WSM419 plasmid pSMED02, complete sequence	654402-654433	7	0.781
NZ_CP046280_2	2.9\|2988585\|32\|NZ_CP046280\|CRISPRCasFinder,CRT,PILER-CR	2988585-2988616	32	NZ_CP021373	Rhizobium sp. ACO-34A plasmid pRACO34Ac, complete sequence	254164-254195	7	0.781
NZ_CP046280_2	2.10\|2988646\|32\|NZ_CP046280\|CRISPRCasFinder,CRT,PILER-CR	2988646-2988677	32	NZ_CP025980	Escherichia marmotae strain HT073016 plasmid pEM148, complete sequence	2635-2666	7	0.781
NZ_CP046280_2	2.10\|2988646\|32\|NZ_CP046280\|CRISPRCasFinder,CRT,PILER-CR	2988646-2988677	32	NZ_CP025980	Escherichia marmotae strain HT073016 plasmid pEM148, complete sequence	31701-31732	7	0.781
NZ_CP046280_2	2.10\|2988646\|32\|NZ_CP046280\|CRISPRCasFinder,CRT,PILER-CR	2988646-2988677	32	NZ_CP025980	Escherichia marmotae strain HT073016 plasmid pEM148, complete sequence	57356-57387	7	0.781
NZ_CP046280_1	1.6\|2978834\|32\|NZ_CP046280\|CRISPRCasFinder,CRT	2978834-2978865	32	NZ_CP018172	Mesorhizobium oceanicum strain B7 plasmid unnamed1, complete sequence	5362-5393	8	0.75
NZ_CP046280_1	1.14\|2978836\|32\|NZ_CP046280\|PILER-CR	2978836-2978867	32	NZ_CP018172	Mesorhizobium oceanicum strain B7 plasmid unnamed1, complete sequence	5362-5393	8	0.75
NZ_CP046280_2	2.2\|2988158\|32\|NZ_CP046280\|CRISPRCasFinder,CRT,PILER-CR	2988158-2988189	32	NZ_CP029452	Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence	2052295-2052326	8	0.75
NZ_CP046280_2	2.2\|2988158\|32\|NZ_CP046280\|CRISPRCasFinder,CRT,PILER-CR	2988158-2988189	32	NC_008826	Methylibium petroleiphilum PM1 plasmid RPME01, complete sequence	343727-343758	8	0.75
NZ_CP046280_2	2.8\|2988524\|32\|NZ_CP046280\|CRISPRCasFinder,CRT,PILER-CR	2988524-2988555	32	NZ_CP013345	Sphingopyxis macrogoltabida strain 203N plasmid unnamed1, complete sequence	41788-41819	8	0.75
NZ_CP046280_1	1.4\|2978712\|32\|NZ_CP046280\|CRISPRCasFinder,CRT	2978712-2978743	32	NZ_CP044185	Salmonella enterica subsp. enterica strain AR-0403 plasmid pAR-0403	38488-38519	9	0.719
NZ_CP046280_1	1.6\|2978834\|32\|NZ_CP046280\|CRISPRCasFinder,CRT	2978834-2978865	32	NZ_LR723669	Rhizobium sp. Khangiran2 plasmid 2	87576-87607	9	0.719
NZ_CP046280_1	1.12\|2978714\|32\|NZ_CP046280\|PILER-CR	2978714-2978745	32	NZ_CP044185	Salmonella enterica subsp. enterica strain AR-0403 plasmid pAR-0403	38488-38519	9	0.719
NZ_CP046280_1	1.14\|2978836\|32\|NZ_CP046280\|PILER-CR	2978836-2978867	32	NZ_LR723669	Rhizobium sp. Khangiran2 plasmid 2	87576-87607	9	0.719
NZ_CP046280_2	2.6\|2988402\|32\|NZ_CP046280\|CRISPRCasFinder,CRT,PILER-CR	2988402-2988433	32	NZ_LT900339	Gluconobacter oxydans 621H isolate WT-DSMZ plasmid 2	160320-160351	9	0.719
NZ_CP046280_2	2.6\|2988402\|32\|NZ_CP046280\|CRISPRCasFinder,CRT,PILER-CR	2988402-2988433	32	NC_006672	Gluconobacter oxydans 621H plasmid pGOX1, complete sequence	160319-160350	9	0.719
NZ_CP046280_2	2.7\|2988463\|32\|NZ_CP046280\|CRISPRCasFinder,CRT,PILER-CR	2988463-2988494	32	MT774388	CrAssphage cr112_1, complete genome	38143-38174	10	0.688
NZ_CP046280_2	2.10\|2988646\|32\|NZ_CP046280\|CRISPRCasFinder,CRT,PILER-CR	2988646-2988677	32	MT446416	UNVERIFIED: Escherichia virus TH47, complete genome	171800-171831	10	0.688

1. spacer 1.6|2978834|32|NZ_CP046280|CRISPRCasFinder,CRT matches to NC_010393 (Phage Gifsy-2, complete genome) position: , mismatch: 0, identity: 1.0

aggatggagaccgtcaggctccggaaactgcc	CRISPR spacer
aggatggagaccgtcaggctccggaaactgcc	Protospacer
********************************

2. spacer 1.6|2978834|32|NZ_CP046280|CRISPRCasFinder,CRT matches to NC_010392 (Phage Gifsy-1, complete genome) position: , mismatch: 0, identity: 1.0

aggatggagaccgtcaggctccggaaactgcc	CRISPR spacer
aggatggagaccgtcaggctccggaaactgcc	Protospacer
********************************

3. spacer 1.8|2978956|33|NZ_CP046280|CRISPRCasFinder,CRT matches to JQ288021 (Salmonella phage SPN3UB, complete genome) position: , mismatch: 0, identity: 1.0

cctcagggatctccggctctacgctgaactccg	CRISPR spacer
cctcagggatctccggctctacgctgaactccg	Protospacer
*********************************

4. spacer 1.8|2978956|33|NZ_CP046280|CRISPRCasFinder,CRT matches to NC_010393 (Phage Gifsy-2, complete genome) position: , mismatch: 0, identity: 1.0

cctcagggatctccggctctacgctgaactccg	CRISPR spacer
cctcagggatctccggctctacgctgaactccg	Protospacer
*********************************

5. spacer 1.8|2978956|33|NZ_CP046280|CRISPRCasFinder,CRT matches to NC_010392 (Phage Gifsy-1, complete genome) position: , mismatch: 0, identity: 1.0

cctcagggatctccggctctacgctgaactccg	CRISPR spacer
cctcagggatctccggctctacgctgaactccg	Protospacer
*********************************

6. spacer 1.14|2978836|32|NZ_CP046280|PILER-CR matches to NC_010393 (Phage Gifsy-2, complete genome) position: , mismatch: 0, identity: 1.0

aggatggagaccgtcaggctccggaaactgcc	CRISPR spacer
aggatggagaccgtcaggctccggaaactgcc	Protospacer
********************************

7. spacer 1.14|2978836|32|NZ_CP046280|PILER-CR matches to NC_010392 (Phage Gifsy-1, complete genome) position: , mismatch: 0, identity: 1.0

aggatggagaccgtcaggctccggaaactgcc	CRISPR spacer
aggatggagaccgtcaggctccggaaactgcc	Protospacer
********************************

8. spacer 1.16|2978958|33|NZ_CP046280|PILER-CR matches to JQ288021 (Salmonella phage SPN3UB, complete genome) position: , mismatch: 0, identity: 1.0

cctcagggatctccggctctacgctgaactccg	CRISPR spacer
cctcagggatctccggctctacgctgaactccg	Protospacer
*********************************

9. spacer 1.16|2978958|33|NZ_CP046280|PILER-CR matches to NC_010393 (Phage Gifsy-2, complete genome) position: , mismatch: 0, identity: 1.0

cctcagggatctccggctctacgctgaactccg	CRISPR spacer
cctcagggatctccggctctacgctgaactccg	Protospacer
*********************************

10. spacer 1.16|2978958|33|NZ_CP046280|PILER-CR matches to NC_010392 (Phage Gifsy-1, complete genome) position: , mismatch: 0, identity: 1.0

cctcagggatctccggctctacgctgaactccg	CRISPR spacer
cctcagggatctccggctctacgctgaactccg	Protospacer
*********************************

11. spacer 1.1|2978529|32|NZ_CP046280|CRISPRCasFinder,CRT matches to CP053320 (Salmonella enterica subsp. arizonae serovar 41:z4,z23:- strain 2016K-0011 plasmid unnamed, complete sequence) position: , mismatch: 1, identity: 0.969

atgtgtaaattttggtgccgttcctgggtttt	CRISPR spacer
atgtgtaaatttgggtgccgttcctgggtttt	Protospacer
************ *******************

12. spacer 1.2|2978590|32|NZ_CP046280|CRISPRCasFinder,CRT matches to CP053320 (Salmonella enterica subsp. arizonae serovar 41:z4,z23:- strain 2016K-0011 plasmid unnamed, complete sequence) position: , mismatch: 1, identity: 0.969

gcgcttgatctcccgttatctaagggccaatc	CRISPR spacer
gcacttgatctcccgttatctaagggccaatc	Protospacer
**.*****************************

13. spacer 1.8|2978956|33|NZ_CP046280|CRISPRCasFinder,CRT matches to KC139516 (Salmonella phage FSL SP-016, partial genome) position: , mismatch: 1, identity: 0.97

cctcagggatctccggctctacgctgaactccg	CRISPR spacer
cctcagggatctccggctctacgctgaactctg	Protospacer
*******************************.*

14. spacer 1.9|2978531|32|NZ_CP046280|PILER-CR matches to CP053320 (Salmonella enterica subsp. arizonae serovar 41:z4,z23:- strain 2016K-0011 plasmid unnamed, complete sequence) position: , mismatch: 1, identity: 0.969

atgtgtaaattttggtgccgttcctgggtttt	CRISPR spacer
atgtgtaaatttgggtgccgttcctgggtttt	Protospacer
************ *******************

15. spacer 1.10|2978592|32|NZ_CP046280|PILER-CR matches to CP053320 (Salmonella enterica subsp. arizonae serovar 41:z4,z23:- strain 2016K-0011 plasmid unnamed, complete sequence) position: , mismatch: 1, identity: 0.969

gcgcttgatctcccgttatctaagggccaatc	CRISPR spacer
gcacttgatctcccgttatctaagggccaatc	Protospacer
**.*****************************

16. spacer 1.16|2978958|33|NZ_CP046280|PILER-CR matches to KC139516 (Salmonella phage FSL SP-016, partial genome) position: , mismatch: 1, identity: 0.97

cctcagggatctccggctctacgctgaactccg	CRISPR spacer
cctcagggatctccggctctacgctgaactctg	Protospacer
*******************************.*

17. spacer 2.8|2988524|32|NZ_CP046280|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP044178 (Salmonella enterica subsp. enterica serovar Concord strain AR-0407 plasmid pAR-0407-1) position: , mismatch: 2, identity: 0.938

tttggtgaaattgttctggctgtcgatgtagc	CRISPR spacer
tttgatgaaattgttctggctgtcgatatagc	Protospacer
****.**********************.****

18. spacer 2.2|2988158|32|NZ_CP046280|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024424 (Paracoccus yeei strain TT13 plasmid pTT13-2, complete sequence) position: , mismatch: 5, identity: 0.844

-acggcaacggatgcgaccgccagcgcgatccc	CRISPR spacer
tgcggc-acggatgaggccgccagcgcgatctc	Protospacer
 .**** ******* *.**************.*

19. spacer 2.2|2988158|32|NZ_CP046280|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP020440 (Paracoccus yeei strain FDAARGOS_252 plasmid unnamed2, complete sequence) position: , mismatch: 5, identity: 0.844

-acggcaacggatgcgaccgccagcgcgatccc	CRISPR spacer
tgcggc-acggatgaggccgccagcgcgatctc	Protospacer
 .**** ******* *.**************.*

20. spacer 2.2|2988158|32|NZ_CP046280|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP044082 (Paracoccus yeei strain FDAARGOS_643 plasmid unnamed4, complete sequence) position: , mismatch: 5, identity: 0.844

-acggcaacggatgcgaccgccagcgcgatccc	CRISPR spacer
tgcggc-acggatgaggccgccagcgcgatctc	Protospacer
 .**** ******* *.**************.*

21. spacer 2.2|2988158|32|NZ_CP046280|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP031080 (Paracoccus yeei strain CCUG 32053 plasmid pYEE2, complete sequence) position: , mismatch: 6, identity: 0.812

-acggcaacggatgcgaccgccagcgcgatccc	CRISPR spacer
tgcggc-acggatgaggccgccagcgcgatctg	Protospacer
 .**** ******* *.**************.

22. spacer 1.3|2978651|32|NZ_CP046280|CRISPRCasFinder,CRT matches to NC_004669 (Enterococcus faecalis V583 plasmid pTEF1, complete sequence) position: , mismatch: 7, identity: 0.781

tggcttataaataaaaggttgag-----gtgtcagta	CRISPR spacer
tggcatataaataaaagggtgagtctttgtgt-----	Protospacer
**** ************* ****     ****

23. spacer 1.3|2978651|32|NZ_CP046280|CRISPRCasFinder,CRT matches to NZ_CP031029 (Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-2, complete sequence) position: , mismatch: 7, identity: 0.781

tggcttataaataaaaggttgag-----gtgtcagta	CRISPR spacer
tggcatataaataaaagggtgagtctttgtgt-----	Protospacer
**** ************* ****     ****

24. spacer 1.3|2978651|32|NZ_CP046280|CRISPRCasFinder,CRT matches to NZ_CP019513 (Enterococcus faecalis strain CLB21560 plasmid pA, complete sequence) position: , mismatch: 7, identity: 0.781

tggcttataaataaaaggttgag-----gtgtcagta	CRISPR spacer
tggcatataaataaaagggtgagtctttgtgt-----	Protospacer
**** ************* ****     ****

25. spacer 1.3|2978651|32|NZ_CP046280|CRISPRCasFinder,CRT matches to NC_002630 (Enterococcus faecalis plasmid pAM373, complete sequence) position: , mismatch: 7, identity: 0.781

tggcttataaataaaaggttgag-----gtgtcagta	CRISPR spacer
tggcatataaataaaagggtgagtctttgtgt-----	Protospacer
**** ************* ****     ****

26. spacer 1.4|2978712|32|NZ_CP046280|CRISPRCasFinder,CRT matches to NC_048066 (Vibrio phage 1.202.O._10N.222.45.E8, partial genome) position: , mismatch: 7, identity: 0.781

acgccatcattgaaagcaatctggcaacgtac	CRISPR spacer
acgccatcattgaaagcaatttggctgtagaa	Protospacer
********************.**** ... *

27. spacer 1.11|2978653|32|NZ_CP046280|PILER-CR matches to NC_004669 (Enterococcus faecalis V583 plasmid pTEF1, complete sequence) position: , mismatch: 7, identity: 0.781

tggcttataaataaaaggttgag-----gtgtcagta	CRISPR spacer
tggcatataaataaaagggtgagtctttgtgt-----	Protospacer
**** ************* ****     ****

28. spacer 1.11|2978653|32|NZ_CP046280|PILER-CR matches to NZ_CP031029 (Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-2, complete sequence) position: , mismatch: 7, identity: 0.781

tggcttataaataaaaggttgag-----gtgtcagta	CRISPR spacer
tggcatataaataaaagggtgagtctttgtgt-----	Protospacer
**** ************* ****     ****

29. spacer 1.11|2978653|32|NZ_CP046280|PILER-CR matches to NZ_CP019513 (Enterococcus faecalis strain CLB21560 plasmid pA, complete sequence) position: , mismatch: 7, identity: 0.781

tggcttataaataaaaggttgag-----gtgtcagta	CRISPR spacer
tggcatataaataaaagggtgagtctttgtgt-----	Protospacer
**** ************* ****     ****

30. spacer 1.11|2978653|32|NZ_CP046280|PILER-CR matches to NC_002630 (Enterococcus faecalis plasmid pAM373, complete sequence) position: , mismatch: 7, identity: 0.781

tggcttataaataaaaggttgag-----gtgtcagta	CRISPR spacer
tggcatataaataaaagggtgagtctttgtgt-----	Protospacer
**** ************* ****     ****

31. spacer 1.12|2978714|32|NZ_CP046280|PILER-CR matches to NC_048066 (Vibrio phage 1.202.O._10N.222.45.E8, partial genome) position: , mismatch: 7, identity: 0.781

acgccatcattgaaagcaatctggcaacgtac	CRISPR spacer
acgccatcattgaaagcaatttggctgtagaa	Protospacer
********************.**** ... *

32. spacer 2.2|2988158|32|NZ_CP046280|CRISPRCasFinder,CRT,PILER-CR matches to NC_009621 (Sinorhizobium medicae WSM419 plasmid pSMED02, complete sequence) position: , mismatch: 7, identity: 0.781

-acggcaacggatgcgaccgccagcgcgatccc	CRISPR spacer
cgcgccga-ggaagcgaccgccagcgcgagccg	Protospacer
 .** *.* *** **************** **

33. spacer 2.9|2988585|32|NZ_CP046280|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021373 (Rhizobium sp. ACO-34A plasmid pRACO34Ac, complete sequence) position: , mismatch: 7, identity: 0.781

ggcccgtccttttgcatggctgcgacaacggg	CRISPR spacer
cggccagcgtttcgcctggctgcgacaacggg	Protospacer
 * **. * ***.** ****************

34. spacer 2.10|2988646|32|NZ_CP046280|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP025980 (Escherichia marmotae strain HT073016 plasmid pEM148, complete sequence) position: , mismatch: 7, identity: 0.781

gacggactggaaaaactcatcatttctgaaga	CRISPR spacer
gaatttctggaaaaactcagcatgtctgaagc	Protospacer
**    ************* *** *******

35. spacer 2.10|2988646|32|NZ_CP046280|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP025980 (Escherichia marmotae strain HT073016 plasmid pEM148, complete sequence) position: , mismatch: 7, identity: 0.781

gacggactggaaaaactcatcatttctgaaga	CRISPR spacer
gaatttctggaaaaactcagcatgtctgaagc	Protospacer
**    ************* *** *******

36. spacer 2.10|2988646|32|NZ_CP046280|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP025980 (Escherichia marmotae strain HT073016 plasmid pEM148, complete sequence) position: , mismatch: 7, identity: 0.781

gacggactggaaaaactcatcatttctgaaga	CRISPR spacer
gaatttctggaaaaactcagcatgtctgaagc	Protospacer
**    ************* *** *******

37. spacer 1.6|2978834|32|NZ_CP046280|CRISPRCasFinder,CRT matches to NZ_CP018172 (Mesorhizobium oceanicum strain B7 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

aggatggagaccgtcaggctccggaaactgcc	CRISPR spacer
gggatggggaccgtcaggctcctgaaggattc	Protospacer
.******.************** ***.   .*

38. spacer 1.14|2978836|32|NZ_CP046280|PILER-CR matches to NZ_CP018172 (Mesorhizobium oceanicum strain B7 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

aggatggagaccgtcaggctccggaaactgcc	CRISPR spacer
gggatggggaccgtcaggctcctgaaggattc	Protospacer
.******.************** ***.   .*

39. spacer 2.2|2988158|32|NZ_CP046280|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP029452 (Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence) position: , mismatch: 8, identity: 0.75

acggcaacggatgcgaccgccagcgcgatccc	CRISPR spacer
cgggccgaggatgcgaccgcgagcgcgagccg	Protospacer
  *** . ************ ******* **

40. spacer 2.2|2988158|32|NZ_CP046280|CRISPRCasFinder,CRT,PILER-CR matches to NC_008826 (Methylibium petroleiphilum PM1 plasmid RPME01, complete sequence) position: , mismatch: 8, identity: 0.75

acggcaac-----ggatgcgaccgccagcgcgatccc	CRISPR spacer
-----aacttcctcgaagcgaccgccaccgcgatccc	Protospacer
     ***      ** ********** *********

41. spacer 2.8|2988524|32|NZ_CP046280|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013345 (Sphingopyxis macrogoltabida strain 203N plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

tttggtgaaattgttctggctgtcgatgtagc	CRISPR spacer
gttagtgaaattgttcttgctgtcggcgtgcg	Protospacer
 **.************* *******..**.

42. spacer 1.4|2978712|32|NZ_CP046280|CRISPRCasFinder,CRT matches to NZ_CP044185 (Salmonella enterica subsp. enterica strain AR-0403 plasmid pAR-0403) position: , mismatch: 9, identity: 0.719

acgccatcattgaaagcaatctggcaacgtac	CRISPR spacer
cggtgattattgaaagcaatctggtaacacaa	Protospacer
  *. **.****************.***..*

43. spacer 1.6|2978834|32|NZ_CP046280|CRISPRCasFinder,CRT matches to NZ_LR723669 (Rhizobium sp. Khangiran2 plasmid 2) position: , mismatch: 9, identity: 0.719

aggatggagaccgtcaggctccggaaactgcc	CRISPR spacer
aagacggagaccgtcaggcgccggaaggattt	Protospacer
*.**.************** ******.   ..

44. spacer 1.12|2978714|32|NZ_CP046280|PILER-CR matches to NZ_CP044185 (Salmonella enterica subsp. enterica strain AR-0403 plasmid pAR-0403) position: , mismatch: 9, identity: 0.719

acgccatcattgaaagcaatctggcaacgtac	CRISPR spacer
cggtgattattgaaagcaatctggtaacacaa	Protospacer
  *. **.****************.***..*

45. spacer 1.14|2978836|32|NZ_CP046280|PILER-CR matches to NZ_LR723669 (Rhizobium sp. Khangiran2 plasmid 2) position: , mismatch: 9, identity: 0.719

aggatggagaccgtcaggctccggaaactgcc	CRISPR spacer
aagacggagaccgtcaggcgccggaaggattt	Protospacer
*.**.************** ******.   ..

46. spacer 2.6|2988402|32|NZ_CP046280|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LT900339 (Gluconobacter oxydans 621H isolate WT-DSMZ plasmid 2) position: , mismatch: 9, identity: 0.719

ctggtcctgttcgcactgataaacgccgtcgc	CRISPR spacer
agccccctgttcgcactcacaaacgccgtcct	Protospacer
    .************ *.********** .

47. spacer 2.6|2988402|32|NZ_CP046280|CRISPRCasFinder,CRT,PILER-CR matches to NC_006672 (Gluconobacter oxydans 621H plasmid pGOX1, complete sequence) position: , mismatch: 9, identity: 0.719

ctggtcctgttcgcactgataaacgccgtcgc	CRISPR spacer
agccccctgttcgcactcacaaacgccgtcct	Protospacer
    .************ *.********** .

48. spacer 2.7|2988463|32|NZ_CP046280|CRISPRCasFinder,CRT,PILER-CR matches to MT774388 (CrAssphage cr112_1, complete genome) position: , mismatch: 10, identity: 0.688

cccggaatatatccctgctgagaatgaaggcg	CRISPR spacer
agaagaagatatcactgctgagaatgataaag	Protospacer
   .*** ***** ************* .. *

49. spacer 2.10|2988646|32|NZ_CP046280|CRISPRCasFinder,CRT,PILER-CR matches to MT446416 (UNVERIFIED: Escherichia virus TH47, complete genome) position: , mismatch: 10, identity: 0.688

gacggactggaaaaactcatcatttctgaaga	CRISPR spacer
atgtcattggaaaaagtaatcatttctgaatt	Protospacer
.    *.******** * ************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

950918 : 965826

Cronobacter_phage(86.67%)

integrase,head,capsid,terminase,tail,portal

attL 950828:950844|attR 967448:967464

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
950828:950844	attL	NA	NA	NA	NA
WP_000290959.1\|950918_951971_-\|integrase	tyrosine-type recombinase/integrase	A0A218M4I3	Erwinia_phage	1.7e-104	55.8
WP_000608639.1\|952066_952747_-	hypothetical protein	NA	NA	NA	NA
WP_000348280.1\|952743_953772_-	hypothetical protein	NA	NA	NA	NA
WP_000108288.1\|953787_954381_-	phage repressor protein CI	F1BUN8	Cronobacter_phage	1.3e-29	35.5
WP_000804006.1\|954473_954695_+	hypothetical protein	NA	NA	NA	NA
WP_000460878.1\|954727_955231_+	hypothetical protein	F1BUN6	Cronobacter_phage	3.5e-60	72.5
WP_000643375.1\|955240_955468_+	hypothetical protein	NA	NA	NA	NA
WP_000996838.1\|955457_955883_+	hypothetical protein	F1BUN5	Cronobacter_phage	7.6e-24	50.4
WP_000022786.1\|955882_956284_+	hypothetical protein	F1BUN2	Cronobacter_phage	1.4e-48	66.9
WP_000057334.1\|956351_956582_+	DUF2732 family protein	NA	NA	NA	NA
WP_156016738.1\|956572_957433_+	Dam family site-specific DNA-(adenine-N6)-methyltransferase	F1BUN1	Cronobacter_phage	1.2e-129	82.3
WP_156016740.1\|957429_959451_+	replication endonuclease	F1BUM9	Cronobacter_phage	2.5e-298	74.8
WP_023199746.1\|959564_959783_+	hypothetical protein	E5G6M0	Salmonella_phage	2.8e-06	49.1
WP_001552031.1\|959756_960080_-	ogr/Delta-like zinc finger family protein	F1BUM8	Cronobacter_phage	8.0e-50	92.3
WP_000038208.1\|960076_961138_-\|portal	phage portal protein	F1BUM7	Cronobacter_phage	2.3e-162	77.1
WP_156017627.1\|962181_962985_+\|capsid	phage capsid protein	F1BUM4	Cronobacter_phage	7.0e-79	56.4
WP_000550496.1\|963046_964069_+\|capsid	phage major capsid protein, P2 family	F1BUM2	Cronobacter_phage	1.1e-158	81.2
WP_001218537.1\|964072_964774_+\|terminase	terminase	F1BUM0	Cronobacter_phage	9.4e-88	66.8
WP_000447487.1\|964834_965323_+\|head	head completion/stabilization protein	F1BUL8	Cronobacter_phage	2.3e-64	82.7
WP_156016742.1\|965319_965826_+\|tail	phage tail protein	F1BUL7	Cronobacter_phage	8.9e-64	69.1
967448:967464	attR	NA	NA	NA	NA

DBSCAN-SWA_2

1000783 : 1008731

Dickeya_phage(16.67%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_088523871.1\|1000783_1001902_+	macrolide transporter subunit MacA	A0A140XAI1	Dickeya_phage	1.4e-08	38.9
WP_023232933.1\|1001898_1003845_+	macrolide ABC transporter ATP-binding protein/permease MacB	G9BWD6	Planktothrix_phage	9.1e-40	42.3
WP_000447499.1\|1003974_1004196_-	cold shock-like protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	9.3e-18	64.2
WP_000520789.1\|1004519_1004840_+\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	4.5e-13	45.7
WP_000934064.1\|1004870_1007147_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	6.2e-165	42.3
WP_094915213.1\|1007475_1008731_-\|transposase	IS3-like element ISSen1 family transposase	Q6H9S3	Enterobacteria_phage	2.2e-18	34.5

DBSCAN-SWA_3

1267193 : 1289290

Salmonella_phage(60.0%)

tail,protease,lysis,holin,integrase

attL 1268482:1268497|attR 1295410:1295425

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000444509.1\|1267193_1268444_+	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	6.7e-20	92.6
1268482:1268497	attL	NA	NA	NA	NA
WP_000741325.1\|1268557_1269700_-\|integrase	tyrosine-type recombinase/integrase	O21929	Phage_21	8.2e-174	80.3
WP_000089141.1\|1269689_1269926_-	excisionase	NA	NA	NA	NA
WP_094883067.1\|1270409_1271090_-	YqaJ viral recombinase family protein	A0A0M3ULE0	Salmonella_phage	2.5e-130	97.8
WP_001652508.1\|1271086_1271872_-	phage recombination protein Bet	A0A0M4RD39	Salmonella_phage	8.2e-149	98.9
WP_079820536.1\|1271877_1272174_-	host-nuclease inhibitor protein Gam	A0A0M5M5Z9	Salmonella_phage	6.0e-44	92.9
WP_000186242.1\|1272264_1272465_-	cell division protein FtsZ	G8C7T2	Escherichia_phage	2.4e-12	48.4
WP_000373339.1\|1272751_1272958_+	hypothetical protein	K7P7I0	Enterobacteria_phage	2.1e-16	67.6
WP_000846936.1\|1272997_1273804_-	DUF3037 domain-containing protein	NA	NA	NA	NA
WP_000097141.1\|1273800_1274649_-	hypothetical protein	NA	NA	NA	NA
WP_001230958.1\|1274820_1275216_-	helix-turn-helix domain-containing protein	K7PM35	Enterobacteria_phage	2.7e-47	72.5
WP_000992433.1\|1275320_1275557_+	hypothetical protein	A0A0M4QX15	Salmonella_phage	1.5e-26	71.8
WP_072208512.1\|1275522_1275897_+	hypothetical protein	S4TTD7	Salmonella_phage	1.2e-62	96.8
WP_156016783.1\|1276089_1277007_+	replication protein	A5VW95	Enterobacteria_phage	5.2e-54	81.3
WP_001537422.1\|1277003_1277699_+	replication protein 14	G8C7U6	Escherichia_phage	5.3e-59	47.4
WP_000273939.1\|1278515_1278776_+	hypothetical protein	NA	NA	NA	NA
WP_001217669.1\|1279059_1279293_+	DinI family protein	H6WRY5	Salmonella_phage	5.6e-37	100.0
WP_014343878.1\|1279409_1279658_+	hypothetical protein	A0A0U2C0C8	Salmonella_phage	1.6e-42	100.0
WP_001750112.1\|1279692_1280295_+	DUF1367 family protein	S4TTI0	Salmonella_phage	2.8e-109	99.0
WP_001096500.1\|1280503_1281115_+	ninG protein	A0A0M4RU10	Salmonella_phage	7.9e-91	97.5
WP_000801757.1\|1281111_1281252_+	YlcG family protein	A0A0M5M7B2	Salmonella_phage	7.2e-08	78.9
WP_156016785.1\|1281248_1281926_+	antiterminator	I6PDF8	Cronobacter_phage	3.3e-61	53.1
WP_000211410.1\|1282198_1282762_+	ORF6N domain-containing protein	A0A0P0ZC44	Stx2-converting_phage	7.6e-56	92.2
WP_060629033.1\|1283268_1283457_+	hypothetical protein	NA	NA	NA	NA
WP_001110787.1\|1283671_1284358_-\|protease	type III secretion system effector protease GogA	Q9MBM2	Phage_Gifsy-1	3.6e-132	99.6
WP_001574216.1\|1284633_1284963_+\|holin	phage holin, lambda family	A0A0M3ULK9	Salmonella_phage	5.8e-56	100.0
WP_000984587.1\|1284946_1285399_+	lysozyme	A0A0M4R365	Salmonella_phage	5.1e-79	98.0
WP_077915163.1\|1285416_1285863_+\|lysis	lysis protein	A0A0M4RD57	Salmonella_phage	5.3e-68	93.9
WP_000669693.1\|1286098_1286500_-	hypothetical protein	NA	NA	NA	NA
WP_072208476.1\|1287311_1288706_+	shikimate transporter	E5G6P0	Salmonella_phage	1.0e-77	48.9
WP_000143179.1\|1288705_1289290_+\|tail	tail fiber assembly protein	A0A0M4RTP2	Salmonella_phage	1.7e-87	84.8
1295410:1295425	attR	NA	NA	NA	NA

DBSCAN-SWA_4

1935898 : 1941379

Salmonella_phage(57.14%)

tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000143159.1\|1935898_1936483_-\|tail	tail fiber assembly protein	A0A0M4RTP2	Salmonella_phage	5.8e-83	80.6
WP_001529204.1\|1936472_1936793_-	hypothetical protein	A0A0M4QWS3	Salmonella_phage	2.9e-44	79.2
WP_156016920.1\|1936764_1938102_-	shikimate transporter	E5G6P0	Salmonella_phage	2.7e-75	51.0
WP_094888543.1\|1938654_1939146_-	DUF1441 family protein	Q9EYD0	Enterobacteria_phage	3.5e-41	55.6
WP_001532317.1\|1939200_1939389_+	hypothetical protein	NA	NA	NA	NA
WP_000789530.1\|1939453_1939621_+	lytic enzyme	NA	NA	NA	NA
WP_001529209.1\|1939877_1940411_-	DUF2514 domain-containing protein	A0A291LBG9	Klebsiella_phage	1.6e-10	42.4
WP_001014089.1\|1940407_1940695_-	glycoside hydrolase family 19 protein	Q8HA86	Salmonella_phage	1.9e-39	95.1
WP_156017637.1\|1940884_1941379_+	RecE	A0A0U2I1R6	Escherichia_phage	7.0e-21	67.6

DBSCAN-SWA_5

2047302 : 2054536

Morganella_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023137091.1\|2047302_2048733_-	DNA cytosine methyltransferase	E5E3X6	Burkholderia_phage	1.0e-104	57.4
WP_000377042.1\|2048806_2049502_-	phosphohydrolase	A0A1D6Y7U0	Golden_Marseillevirus	2.8e-07	27.1
WP_000107432.1\|2049593_2049893_-	hypothetical protein	NA	NA	NA	NA
WP_156016944.1\|2050542_2051721_+	porin OmpS1	Q1MVN1	Enterobacteria_phage	4.3e-109	57.0
WP_024131163.1\|2051979_2052168_-	hypothetical protein	NA	NA	NA	NA
WP_000208509.1\|2052178_2052391_-	cold-shock protein	A0A1W6JNX5	Morganella_phage	3.9e-21	70.0
WP_000457656.1\|2052845_2054114_-	Y-family DNA polymerase	I6RSM4	Salmonella_phage	4.9e-228	92.4
WP_000394197.1\|2054116_2054536_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	8.5e-36	60.5

DBSCAN-SWA_6

2162731 : 2172636

Enterobacteria_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_156016969.1\|2162731_2163835_-	aminotransferase class V-fold PLP-dependent enzyme	E5ES42	Bathycoccus_sp._RCC1105_virus	3.2e-42	32.8
WP_156017640.1\|2163864_2164263_-	WxcM-like domain-containing protein	NA	NA	NA	NA
WP_156016971.1\|2164258_2164810_-	dTDP-4-dehydrorhamnose 3,5-epimerase	H9NC63	Sphingomonas_phage	4.7e-26	39.8
WP_156016973.1\|2164840_2165656_-	glycosyltransferase	NA	NA	NA	NA
WP_156016976.1\|2165684_2166557_-	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	2.5e-106	64.5
WP_156016977.1\|2166604_2167504_-	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	8.8e-30	36.0
WP_156016979.1\|2167503_2168589_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	1.8e-101	53.1
WP_156016981.1\|2168965_2169859_-	GalU regulator GalF	A0A127AW70	Bacillus_phage	4.8e-44	42.2
WP_001606097.1\|2170085_2171081_-	NAD-dependent epimerase/dehydratase family protein	A0A1V0QG29	Shearwaterpox_virus	1.5e-09	25.6
WP_156016983.1\|2171232_2172636_-	colanic acid biosynthesis protein WcaM	A0A291LBB9	Klebsiella_phage	1.5e-20	32.3

DBSCAN-SWA_7

2239832 : 2249003

Enterobacteria_phage(71.43%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023137006.1\|2239832_2241866_+\|tRNA	methionine--tRNA ligase	A0A1V0SDF2	Indivirus	1.0e-54	27.6
WP_000703136.1\|2242106_2242565_+	YehR family lipoprotein	Q9EYF5	Enterobacteria_phage	7.6e-54	73.2
WP_156016999.1\|2242736_2243267_+	DUF1307 domain-containing protein	Q9EYF5	Enterobacteria_phage	9.5e-16	38.1
WP_156017001.1\|2243323_2243791_-	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	5.7e-73	89.7
WP_000598637.1\|2243837_2244557_-	two-component system response regulator BtsR	NA	NA	NA	NA
WP_000272850.1\|2244553_2246239_-	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	4.8e-279	91.3
WP_001240416.1\|2246461_2247193_+	HTH-type transcriptional regulator MlrA	Q9EYF2	Enterobacteria_phage	4.5e-101	87.9
WP_001261696.1\|2247252_2247360_+	protein YohO	NA	NA	NA	NA
WP_000824854.1\|2247340_2248072_-	ABC transporter permease	NA	NA	NA	NA
WP_000569166.1\|2248055_2249003_-	ABC transporter ATP-binding protein	F2Y1V5	Organic_Lake_phycodnavirus	3.7e-10	27.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP046281

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 14391

Vibrio_phage(12.5%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094888772.1\|1031_1520_-	cytoplasmic protein	NA	NA	NA	NA
WP_094888771.1\|1777_2893_+	DNA-binding protein	NA	NA	NA	NA
WP_094888778.1\|3011_3749_+	3'-5' exonuclease	K7RFY5	Vibrio_phage	1.3e-26	36.0
WP_094888770.1\|3801_4197_+	hypothetical protein	NA	NA	NA	NA
WP_094915154.1\|4193_4805_+	DUF2913 family protein	NA	NA	NA	NA
WP_000728919.1\|4801_5743_-\|transposase	Rpn family recombination-promoting nuclease/putative transposase	Q2A0A7	Sodalis_phage	4.7e-74	54.7
WP_156017682.1\|5883_6024_+	hypothetical protein	NA	NA	NA	NA
WP_080188499.1\|6157_7363_+	ParA family protein	A0A077SL49	Escherichia_phage	3.1e-163	69.3
WP_077917409.1\|7359_8337_+	ParB/RepB/Spo0J family partition protein	A0A1B0V750	Salmonella_phage	1.1e-83	53.2
WP_156017685.1\|8418_9693_-	translesion error-prone DNA polymerase V subunit UmuC	F1C5A5	Cronobacter_phage	4.7e-154	64.0
WP_094888767.1\|10294_10834_-	DNA breaking-rejoining protein	A0A2H4J5W2	uncultured_Caudovirales_phage	1.0e-62	59.6
WP_156017688.1\|11003_11201_+	hypothetical protein	NA	NA	NA	NA
WP_023197482.1\|11606_12113_+	antirestriction protein	A0A1I9S7Y0	Rhodococcus_phage	1.1e-08	28.9
WP_020833574.1\|12155_12347_+	hypothetical protein	NA	NA	NA	NA
WP_114053208.1\|13284_13506_-	hypothetical protein	NA	NA	NA	NA
WP_065680751.1\|13836_14391_+	single-stranded DNA-binding protein	A0A0A0P1Q9	Enterobacteria_phage	3.3e-51	74.0

DBSCAN-SWA_2

36556 : 38095

Stx2-converting_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094915202.1\|36556_38095_+\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	2.2e-275	92.4

DBSCAN-SWA_3

51399 : 53452

Macacine_betaherpesvirus(50.0%)

integrase

attL 43488:43501|attR 54103:54116

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
43488:43501	attL	NA	NA	NA	NA
WP_094915158.1\|51399_52140_+\|integrase	site-specific integrase	I3WFA4	Macacine_betaherpesvirus	5.4e-25	58.6
WP_140428183.1\|52462_53452_-	RepB family plasmid replication initiator protein	J9Q7H0	Salmonella_phage	5.0e-103	64.3
54103:54116	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP046280

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP046281

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection