CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_AP021885	Melissococcus plutonius strain DAT1033	1 crisprs	cas3,DinG,DEDDh,csa3,cas2,cas1,cas7,cas8c,cas5	0	0	3	0
NZ_AP021886	Melissococcus plutonius strain DAT1033 plasmid pMP1, complete sequence	1 crisprs	NA	0	1	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_AP021885_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP021885_1

1443210-1443301

TypeI

Consensus_repeat	Method
ACTCACTCTATAAAGAGTGAGAC	CRISPRCasFinder

1 spacers

cas2,cas1,cas7,cas8c,cas5

The CRISPR arrays of NZ_AP021885_1

>merge|NZ_AP021885|1|1443210-1443301|CRISPRCasFinder
ACTCACTCTATAAAGAGTGAGACGAATTTCTTCACCGTTATCTTCAATACTTGATAAAAATTTCAATCCACTCACTCTATGAAGAGTGAGAC

>NZ_AP021885|1|1|1443210-1443301|CRISPRCasFinder
ACTCACTCTATAAAGAGTGAGAC	GAATTTCTTCACCGTTATCTTCAATACTTGATAAAAATTTCAATCC
ACTCACTCTATGAAGAGTGAGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP021885.1\|WP_013774549.1\|1448259_1448979_-\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|273847
NZ_AP021885.1\|WP_048589976.1\|1440444_1441212_-\|phosphonate-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226164
NZ_AP021885.1\|WP_048589975.1\|1439668_1440448_-\|phosphonate-ABC-transporter,-permease-protein-PhnE	unknown	unknown	gnl\|CDD\|273441
NZ_AP021885.1\|WP_013774531.1\|1433816_1434248_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP021885.1\|WP_013774548.1\|1446308_1448258_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	gnl\|CDD\|378245
NZ_AP021885.1\|WP_048589980.1\|1456390_1457251_-\|rhamnulose-1-phosphate-aldolase	unknown	unknown	gnl\|CDD\|131673
NZ_AP021885.1\|WP_048589973.1\|1432331_1433516_-\|methionine-adenosyltransferase	unknown	unknown	gnl\|CDD\|235374
NZ_AP021885.1\|WP_013774527.1\|1427635_1428310_+\|phosphatase-PAP2-family-protein	unknown	unknown	gnl\|CDD\|239486
NZ_AP021885.1\|WP_013774557.1\|1457281_1458535_-\|L-rhamnose-isomerase	unknown	unknown	gnl\|CDD\|179217
NZ_AP021885.1\|WP_013774537.1\|1438889_1439669_-\|phosphonate-ABC-transporter,-permease-protein-PhnE	unknown	unknown	gnl\|CDD\|273441
NZ_AP021885.1\|WP_048589974.1\|1434519_1435683_-\|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl\|CDD\|236304
NZ_AP021885.1\|WP_048589977.1\|1443759_1444791_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NZ_AP021885.1\|WP_013774554.1\|1453566_1454145_-\|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|197609
NZ_AP021885.1\|WP_013774555.1\|1454832_1456302_+\|peptide-MFS-transporter	unknown	unknown	gnl\|CDD\|225646
NZ_AP021885.1\|WP_013774547.1\|1445441_1446305_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	gnl\|CDD\|187820
NZ_AP021885.1\|WP_013774528.1\|1428325_1429318_+\|TIGR01212-family-radical-SAM-protein	unknown	unknown	gnl\|CDD\|224163
NZ_AP021885.1\|WP_013774543.1\|1443460_1443751_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_AP021885.1\|WP_013774530.1\|1430701_1432168_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|341045
NZ_AP021885.1\|WP_013774553.1\|1452356_1453133_-\|pyrroline-5-carboxylate-reductase	unknown	unknown	gnl\|CDD\|223422
NZ_AP021885.1\|WP_013774529.1\|1429292_1429856_+\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|377744

Protein	Function_ID	Function_description	E-value
NZ_AP021885.1\|WP_013774549.1\|1448259_1448979_-\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|273847	TIGR01876, cas_Cas5d, CRISPR-associated protein Cas5, subtype I-C/DVULG. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum. This family belongs to a set of several Cas protein families, one each for a number of different CRISPR/Cas subtypes, that share a region of N-terminal sequence similarity modeled by TIGR02593. This family represents the Dvulg subtype of CRISPR/Cas locus.	3.59737e-79
NZ_AP021885.1\|WP_048589976.1\|1440444_1441212_-\|phosphonate-ABC-transporter-ATP-binding-protein	gnl\|CDD\|226164	COG3638, COG3638, ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism].	1.24482e-123
NZ_AP021885.1\|WP_048589975.1\|1439668_1440448_-\|phosphonate-ABC-transporter,-permease-protein-PhnE	gnl\|CDD\|273441	TIGR01097, PhnE, phosphonate ABC transporter, permease protein PhnE. Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions].	3.29402e-80
NZ_AP021885.1\|WP_013774555.1\|1454832_1456302_+\|peptide-MFS-transporter	gnl\|CDD\|225646	COG3104, PTR2, Dipeptide/tripeptide permease [Amino acid transport and metabolism].	1.34207e-152
NZ_AP021885.1\|WP_013774548.1\|1446308_1448258_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	5.11567e-150
NZ_AP021885.1\|WP_048589980.1\|1456390_1457251_-\|rhamnulose-1-phosphate-aldolase	gnl\|CDD\|131673	TIGR02624, Rhamnulose-1-phosphate_aldolase, rhamnulose-1-phosphate aldolase. Members of this family are the enzyme RhaD, rhamnulose-1-phosphate aldolase.	1.85291e-164
NZ_AP021885.1\|WP_048589973.1\|1432331_1433516_-\|methionine-adenosyltransferase	gnl\|CDD\|235374	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated.	0
NZ_AP021885.1\|WP_048589977.1\|1443759_1444791_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NZ_AP021885.1\|WP_013774557.1\|1457281_1458535_-\|L-rhamnose-isomerase	gnl\|CDD\|179217	PRK01076, PRK01076, L-rhamnose isomerase; Provisional.	0
NZ_AP021885.1\|WP_013774537.1\|1438889_1439669_-\|phosphonate-ABC-transporter,-permease-protein-PhnE	gnl\|CDD\|273441	TIGR01097, PhnE, phosphonate ABC transporter, permease protein PhnE. Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions].	1.39737e-67
NZ_AP021885.1\|WP_048589974.1\|1434519_1435683_-\|N-acetylmuramoyl-L-alanine-amidase	gnl\|CDD\|236304	PRK08581, PRK08581, amidase domain-containing protein.	6.03524e-66
NZ_AP021885.1\|WP_013774527.1\|1427635_1428310_+\|phosphatase-PAP2-family-protein	gnl\|CDD\|239486	cd03392, PAP2_like_2, PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	4.7259e-45
NZ_AP021885.1\|WP_013774554.1\|1453566_1454145_-\|LysM-peptidoglycan-binding-domain-containing-protein	gnl\|CDD\|197609	smart00257, LysM, Lysin motif.	8.40829e-11
NZ_AP021885.1\|WP_013774547.1\|1445441_1446305_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|187820	cd09689, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Csd2 family.	2.15947e-122
NZ_AP021885.1\|WP_013774528.1\|1428325_1429318_+\|TIGR01212-family-radical-SAM-protein	gnl\|CDD\|224163	COG1242, COG1242, Predicted Fe-S oxidoreductase [General function prediction only].	4.29068e-178
NZ_AP021885.1\|WP_013774543.1\|1443460_1443751_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	9.48819e-29
NZ_AP021885.1\|WP_013774530.1\|1430701_1432168_-\|MFS-transporter	gnl\|CDD\|341045	cd17502, MFS_Azr1_MDR_like, Saccharomyces cerevisiae Azole resistance protein 1 (Azr1p), and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of multidrug resistance (MDR) transporters including various Saccharomyces cerevisiae proteins such as azole resistance protein 1 (Azr1p), vacuolar basic amino acid transporter 1 (Vba1p), vacuolar basic amino acid transporter 5 (Vba5p), and Sge1p (also known as Nor1p, 10-N-nonyl acridine orange resistance protein, and crystal violet resistance protein). MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. This subfamily belongs to the Methylenomycin A resistance protein (also called MMR peptide) and similar multidrug resistance (MDR) transporters (MMR-like MDR transporter) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.58923e-59
NZ_AP021885.1\|WP_013774553.1\|1452356_1453133_-\|pyrroline-5-carboxylate-reductase	gnl\|CDD\|223422	COG0345, ProC, Pyrroline-5-carboxylate reductase [Amino acid transport and metabolism].	2.28059e-74
NZ_AP021885.1\|WP_013774529.1\|1429292_1429856_+\|methyltransferase-domain-containing-protein	gnl\|CDD\|377744	pfam06962, rRNA_methylase, Putative rRNA methylase. This family contains a number of putative rRNA methylases. Note that many family members are hypothetical proteins.	2.52913e-70

>NZ_AP021885.1|WP_048589976.1|1440444_1441212_-|phosphonate-ABC-transporter-ATP-binding-protein
MIQFEHVTKTYPNGVKGLKDINLTIEAGEFVSIIGLSGAGKSTLLRLINRLNEISEGNISINGLSITKAKKNELRKIRRNIGMIFQHFNLVRKSSVQKNVLSGRLGYYSTFKSILGIFSKEDYKLVNDALTRVGMLDKLHERSDALSSGQQQRISIARTLVQQASTILADEPVASLDPITTQMIMKDLKKINQDLKCTVILNLHSVGLARDFSSRIIGLRAGEIVFDGTPEEATDEVLTEIYGADILKSKEEEAI
>NZ_AP021885.1|WP_048589975.1|1439668_1440448_-|phosphonate-ABC-transporter,-permease-protein-PhnE
MKLKDTIHRNLYKHLFIIFLILICICVSGQITEADPLEVFNNADQISEFLQRFFHPDWQYLPKIIEPILKTIKISVVGTILGVIFAVPFACLGTTTITRNPIITTILRFFMSIIRTIPNLLLAALFVAMIGIGEFTGVLTIAVFTFGMVSQLIYEAIETVEHGTIEAADSVGATKTQVAFWVILPQISHQIFGYALYAFEINVRASTVLGYVGAGGIGVILNSSLSLLRYDRVSIIILAILIVVTIIDWISEIIRKKLI
>NZ_AP021885.1|WP_013774537.1|1438889_1439669_-|phosphonate-ABC-transporter,-permease-protein-PhnE
MRKADKVKNYSIIIFLIFVIVYSVFGIDYSGIDKISLVAIKSVLVGLFHPDWQFIYDGSGEDLISLLFLTICIAFLGTLIATFLALPLTLLGARTLWKTHPWIAKIGKFICNVLRAFPELVYAIIFVKVVGPGPFAGVLAIGIHQIGMLGKLYIEELEAMNEEVIESMDAVGAGFWQTTFFARVPELAPTCFSLALNHFEIAVRSAATLGLVGAGGIGAPMIFAIQARSWNKVGIILLGIIFTVFVIDTATGYLRKKLQ
>NZ_AP021885.1|WP_048589974.1|1434519_1435683_-|N-acetylmuramoyl-L-alanine-amidase
MKQKILPIVVSATLFSSALLLPTTSFAEKLTKPSVSVTSENSQSKNETVESSITTSETHQSTESGSSSTSTPSSSTTSSQETESSSSNGGISNHLPAEKPVIPSKEQQSKKESKTTNTVPVIEDKKEGKPVLEHTTIPNLDKIVVTKNQTTEEFIKKIGESARQVAHQYDLYASVMIAQAILESGSGNSGLASEPNYNLFGIKGEYDGASIVMKTQEDNGKGNLYTIDSAFRKYPSYKESLEDYAKLLKEGLTGNKDYYHGTWKSQTTSYKEATHFLMGRYATDTQYAEKLNQLIDVYNLTAYDEWHEENDAAAHATPMAIKKAAEEKKAEQKKKEKHMDTVKAATKALNNRMEQIKKRKEERTKTFLTQPQQFLFQLLINKNDSVK
>NZ_AP021885.1|WP_013774531.1|1433816_1434248_-|hypothetical-protein
MYSYTDMILTIMQRVEVYNEIFKAISKEIQEHNYNQELSKKGHDTYIFCRNNVNRFLMEDEGFRKNLKSVQEKEATKILLTGLDTYKEGIYFLLKSLNEQGEIIDPFKFELGLKEKNAAFKLINQACREACEGIRSAHSVHKM
>NZ_AP021885.1|WP_048589973.1|1432331_1433516_-|methionine-adenosyltransferase
MTEKLLFTSESVSEGHPDKVADQISDAILDAILEKDPMARVACETSVTTGLVLVFGEISTTAYVDIQKIVRQTIKDIGYTRANYGFDGDLVAVLVALDEQSSDIAMGVDEALETKEKKETDEIGAGDQGLMFGFAIDETPELMPLPIALSHRLVHRLAQLRKENHLAYLRPDAKSQVTVEYDDQQQPKRIDTIVISTQHDSNVSLEQIEKDMKELVINEVIPANLLDENTKYFINPTGRFVIGGPQGDAGLTGRKIIVDTYGGFSRHGGGAFSGKDATKVDRSASYAARYIAKNIVAAGLAKKVEVQLAYAIGVAQPVSISIDTFGTNTVPEDALIQAVRDNFDLRPAGIIDMLDLRKPIYRQTAAYGHFGRTDIDLPWERTDKVDVLKANLEK
>NZ_AP021885.1|WP_013774530.1|1430701_1432168_-|MFS-transporter
MERKTNVKFVTICLFIATFMTAIEGTIVTTAMPTIIGSLHGIGIMNWVFSIYLLTNAMLTPIYGKLADKIGRKPVFTIGILIFILGSSLCGLSQTMITLIIARTIQGVGAGAILPVSLTILADLYTINKRAKIMGLNNASWGIASVFGPLAGGFIVDTFSWHWIFFINVPIGILVLALIHYYLIEPKRPKSTVPIDVLGSIALMITLLTLLLGFQLMGDYGISWLIFACFGCACLFFILFIFIEKRVQDPVIDLTLFHQSTFVLVNLMATLIYGFLAGVESYIPIWMQDVLGKSAGIGGLALAPMSLLWMVGSFIASHLIGKYSLKKVLVIGLGLIFLGSLGLAFASETLAFIWFFGITSILGCGFGISSTTTTLASQNSVASEKLSIATSLNTLVRTLGQTIMAAVFGVLLNNVMAAKLAESSLPVNNDVLNQLVNPSTVDKIPEKWLLPLKKILYEGLHSIYLVGCILVLIAFLIAFLLKNNKIDD
>NZ_AP021885.1|WP_013774529.1|1429292_1429856_+|methyltransferase-domain-containing-protein
MLETALQYSHFLLNEIICPGDHVVDATMGNGNDTLFLAKLVGDKGKVYAFDIQKQALERTRQRLIENQVIQCTELFQQGHETIEQVLPIETTLSAAIFNLGYLPKSDKEIVTLPETTIQAIEQLLIRLKSKGRLLLVIYYGHSGGQEELKAVSCYCQQLPQEQFNVLSYQFINQKNQPPILFCIEKK
>NZ_AP021885.1|WP_013774528.1|1428325_1429318_+|TIGR01212-family-radical-SAM-protein
MKKFIYTDDPNKRYYSWNYALRKVFGKKIFKVPIDAGFDCPNRDGTVAKGGCTFCSVSGSGDMIVAPNEPLPIQFRKEIQLMEKKWPNVEQYIVYFQNFTNTHAPVEIIRHRFEQVINEKGVVGLSIGTRPDCLPEETIDYLAELNERFYLWVELGLQTTFEKTSNQINRAHDYQTYLTSVEKLRQHNIRVCTHLINGLTGESFEMMRDNVRRTLLDSDIQGIKLHLLHLMTNTKMIQDYHEGRLKLMTQEDYVAIICDQLEMIPPEIIIHRLTGDAPANSLIGPMWSLKKWEVLNAIDKELERRNSYQGKYDIRKTKEVIFNARNSTTV
>NZ_AP021885.1|WP_013774527.1|1427635_1428310_+|phosphatase-PAP2-family-protein
MKHRKQKNSTHFYLLLGSFFLCLFIFLSAIVYFSPESLSEFDSTLTSWSRIFYPHLNTFFKWYTKLANSSVFGVLAIVFAIILAKFKYYAEALWLLINTALIAGVVNTLIKLFISRERPALNHLVTSHNSSYPSGHSIGSILLYGTLVVLMPLFIKNKKVCRLVQYITSIGIFLIGVSRVYTGVHFPSDILGGFLLGLAWLFLSYPVYLNYRFSLPFKQKRKHG
>NZ_AP021885.1|WP_013774543.1|1443460_1443751_-|CRISPR-associated-endonuclease-Cas2
MLVLITYDVSTTTRNGQQRLRKVAKKCQDHGIRVQNSVFECVVDNTQLTKLRKELIDLIDEQVDSLRIYRLGNNYKTKIEHIGAKATFNIEEPLIF
>NZ_AP021885.1|WP_048589977.1|1443759_1444791_-|type-I-C-CRISPR-associated-endonuclease-Cas1
MRKLLNTIFITTPKSYLALDGQNLLIKMEDDQKHRMPLHNIEAIITTGYPGISPALMRMCADQNITITFLTSSGKFGCRVVGKTSGNVYLRKKQYQVSEDEMGSLTIARNFIIGKLYNQRWMLERMIREHTLKINVTYFKQISQELKSFIEDISFVQNLDTLRGIEGQAASRYFSLFDQMILQQKEDFRFYSRNRRPPLDNVNALLSFTYTLLSQECTSALEMVGLDPYVGFMHQDRPGRTSLAQDLMEELRGIFADRFILTLINKKMMTKKDFIKKENGTVLLTDEARKRFFLAWQKKKNETIQHPFLGEKITWGIVPYAQALLLSRFLRGDLDGYPPFLWK
>NZ_AP021885.1|WP_013774547.1|1445441_1446305_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MGVLQNKIDFKVVVSVANANPNGDPLNGNRPRQNFDGFGEISDVAIKRKIRNRLQDMQEKIFVQSDDRTDDGITSLKDRVESVEELKKIAADKKKADVDRFSEVACETWLDTRSFGQVFAFKGLELSVGVRGPVSIQMGISLDPIDINSLQITKSVNSVNGNGGKSSDTMGMKHFVDFGVYVFNGSINVQLAEKTKFSEEDAEKIKQALITLFENDASAARPDGSMVVEKIYWWKHPNKLGKYSSAKVHRSVKIEKNKGIDRPKSIEDYHFEVEQLEGIQLIELAGY
>NZ_AP021885.1|WP_013774548.1|1446308_1448258_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MSWLADLYQTYENNLDQVGKPIRNIWGKEVILLPISHAYQNAQIEVIIKPTGEFYKAKVIPKEEAATMIPVTIESAGRTSKPMPHGLHDNLQYVAGDYIQYGGDAKKGESFQKYIANLERWCASDFSHPKVQAILTYLKKGTLITDLINYQDEESHQPILIEREGKLVAKWKKEFGEKPEIFSVLASDQFSSFVRFDIYDLNLDAIPVWKDLAISDAFIDYYTTQLSWGGLDYITGKQVPLTENHPSKIRYGGDMAKLISGNDTTNFTFRGRFSEKNQVATIGYETSQKGHNALKWLISKQGKIIDGRVFLTWGEKSVDNLPAVDESSDAIFAEDKETDSITTIDKTSQDFSKSFIKALQGYQQDLRHDQNIHIMILDSATPGRMGILYYRSMEQESYLERLKNWHNQTGWWHAAGWQNAFYGAPSLRTIAEAVHGKRASETLIKNTMTQLFSCVVDNRKMPFNIMQGLLKNASNPLSMELWEWRKTVEIACSVIKHYFYDLEEEYTVALNKEEKDRSYLFGRLLAVADKAEDLALFIQYGEKDKKKQDNDKEKNKDKKERTTNALRYMNAFSNHPVTTWKILQENLIPYYEKLEDKGNYYQNLINQIMTQFDIDDYTDRALTGKYLLGYSSQRIELNNKDKNKDKEEK
>NZ_AP021885.1|WP_013774549.1|1448259_1448979_-|type-I-C-CRISPR-associated-protein-Cas5
MRNQISFLVEGEYALFTDPLTKMGGEKWTYPIPTYQALKGITESIYWKPTIIYYIDEVRIMNPIQMETKGIRLMKYNESNASDLAYYTYLKKPKYEVKVHFEFNKNRPDLKLDWNEDKHYQILKRSIKAGGRRDIFLGTRECQGYIEPIEFGREKGSYDEYEEEMNFNTMVHGLSYPDETGKEELLVRLWQPKMVRGIIKFPRPEACSLCRSLKSMNMKPFSIDTIESAELLARSLEEE
>NZ_AP021885.1|WP_013774553.1|1452356_1453133_-|pyrroline-5-carboxylate-reductase
MIGIIGAGQMGGALIKRFIHSSKFSAKDILVKGGKSNTAKKLQEELQFNLTDTLNDFEDCQMIILATNNASILSVLTDLGDRIKEKQIPILSVAAGVSLKDMQEIMGEMYPLAHCIPNTPVQVNEGILAITYVETIESEKKQTMQAILSVLGRIVEVPEIQLDIFGTIAGCGPAFVDVFIEALSDAAVLNGMPRAISYEIAAQMMKGTAELALKTNQHPGELKDSVTSPGGTTIKGIVALEKNGFRHAVIDGINEIMK
>NZ_AP021885.1|WP_013774554.1|1453566_1454145_-|LysM-peptidoglycan-binding-domain-containing-protein
MRSLNTILLGTTLAAGIGLCLGTSNAHADSVYTVQSGDTLSSISQKFNGDSQLIQQIARDNSISNLNMIYKGQQLTIKTTNEIRETQTAPTNTVVELQPVITEEPVVQNQSTASTPVTTNTSSAKEWLAQRESGGSYSAMNGRYIGKYQLDASYLNGDYSPENQERVADNYITQRYGSWEGAQAFWQANGWY
>NZ_AP021885.1|WP_013774555.1|1454832_1456302_+|peptide-MFS-transporter
MNDNQSDGSFLGQPKGLSTLFFTEMWERFSYYGMRAILLYYIYDTVANGGLGFPKETGLSIMSIYGSMVFMSSIIGGWISDRWLGSQKTVFFGGLFIMIGHIVLATPFGVSALFVSIFFIVIGTGMLKPNVSDMVGHLYSKTDLRRDSGFSIFYMGINIGALVAPLVVGTLGQEYNYHLGFSIAAIGMFFGLVQFYYKSKTTLAGIGLEPTNPMTNQEKKRFGMILLGVLVFAAIVFGGAAFMSKLTVDFFITIISILGILLPIYYFIKMLTAKNVTPDEKTKVMAYIPLFLAAIVFWSLEEQGSSILALFAADRTRHHLFGIPIAASWFQSLNPVFVVILTPVFVTLWTKLGKHQPSTVVKFALGLIFAGLAYVLLMFPGLLYGTNHKVSPLWLIISFFVIIVGEMCLSPVGLSVTTKLAPKAFEAQTVAIWLLADAASQATNAQIARFYTPHTESAYFGTIGIIAVVVGILLILVKKPIKRLMGSIN
>NZ_AP021885.1|WP_048589980.1|1456390_1457251_-|rhamnulose-1-phosphate-aldolase
MKKIDVLQSFFVKEMIEVTDNLYRLGWDERNGGNISYLLTEEEILPFVDLNHYLRKIPIEFDEIALEGKYFLVTGSGKYFKNIATTPAENIGLVCIVDRGASLAVLWGLENNTMPTSELPSHFMSHIARLEVDPENRIIMHNHANHLLAMTFTHELTEKAFTRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGQATAEKMKRTRLVIWPHHGVYGAGKSMDEVFGLIETAEKAAQTYTYVCAQGPILQTISDENLQKLADSFGVVPRSGYLDQAISIASDNKVYN
>NZ_AP021885.1|WP_013774557.1|1457281_1458535_-|L-rhamnose-isomerase
MTSIKQRYEEAKETYQTIGVNTDEVLKRLDEVKISMNVWQGDDIKGFLSDEELSGGISVTGNYPGVARTPKELRQDLEKAYQMIPGKHKLNLHAIYLDTDEKVDLNEIEPKHFKPWVDWAKKQELGLDFNPTFFSHPMFKDGFTLAHPNNEVRDFWIEHGKRSRKIAEYFGEALGQVCVNNFWVPDGYKDSPIDRLTPRRHLMEALDEIFSEDMNPDYTLDAVESKLFGIGLEAYTVGSHEFYMGYGLTRGKLICMDAGHFHPTEVISNKLSAVALFSKGIFLHVSRPMRWDSDHVVIMDDELQEIGRELVRNNLLQKAHIGLDFFDATINRVAAWVIGTRNTQKAVLKAMLEPTDYLKKVELEMDFTTRLAMVEELKDYPFADVWNYYCELKGVPVGLNWLNEIQDYEKNVLSLRS

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

341913 : 350377

Streptococcus_phage(66.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013773520.1\|341913_342558_+	dTMP kinase	M1PSC7	Streptococcus_phage	4.5e-52	50.5
WP_013773521.1\|342576_342906_+	protein from nitrogen regulatory protein P-II (GLNB) family	NA	NA	NA	NA
WP_013773522.1\|342905_343874_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	8.3e-34	31.7
WP_013773523.1\|343867_344704_+	stage 0 sporulation family protein	NA	NA	NA	NA
WP_013773524.1\|344706_345054_+	DNA replication initiation control protein YabA	NA	NA	NA	NA
WP_015695238.1\|345157_346024_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	1.8e-80	55.4
WP_013773526.1\|346223_347336_+	DNA polymerase IV	D0R0A3	Streptococcus_phage	1.6e-12	25.7
WP_013773527.1\|347534_348137_-	anaerobic ribonucleoside-triphosphate reductase activating protein	A0A288TZV3	Enterococcus_phage	3.9e-50	54.7
WP_013773528.1\|348184_350377_-	anaerobic ribonucleoside-triphosphate reductase	A0A0C5KKX3	Enterococcus_phage	4.3e-280	64.4

DBSCAN-SWA_2

832423 : 937038

119

Enterococcus_phage(14.0%)

capsid,protease,bacteriocin,plate,tail,holin,head,terminase,integrase,tRNA,portal

attL 888556:888590|attR 944834:944868

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013773960.1\|832423_833656_+\|tRNA	CCA tRNA nucleotidyltransferase	H7BUW3	unidentified_phage	2.5e-43	48.8
WP_013773961.1\|833642_834008_+	hypothetical protein	NA	NA	NA	NA
WP_041363479.1\|834119_834572_+	hypothetical protein	NA	NA	NA	NA
WP_013773963.1\|835266_836142_+	shikimate dehydrogenase	NA	NA	NA	NA
WP_048589807.1\|836167_837196_+	3-deoxy-7-phosphoheptulonate synthase	NA	NA	NA	NA
WP_013773965.1\|837198_838272_+	3-dehydroquinate synthase	NA	NA	NA	NA
WP_013773966.1\|838273_839440_+	chorismate synthase	A0A291AU41	Pandoravirus	6.0e-39	34.6
WP_048589819.1\|839567_840851_+	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_013773968.1\|840866_841376_+	shikimate kinase	NA	NA	NA	NA
WP_013773969.1\|841642_841885_+	hypothetical protein	NA	NA	NA	NA
WP_013773970.1\|841897_843973_+	sodium:proton antiporter	NA	NA	NA	NA
WP_048589808.1\|844036_845923_+	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L0W2	Tupanvirus	2.8e-54	30.2
WP_013773972.1\|845938_846886_+	thymidylate synthase	A0A0N9SH48	Staphylococcus_phage	2.5e-107	59.6
WP_013773973.1\|846911_847418_+	dihydrofolate reductase	A0A0N9S8H6	Staphylococcus_phage	3.5e-28	44.9
WP_013773974.1\|847537_848158_-	transcriptional repressor LexA	A0A1B1P7Q3	Bacillus_phage	1.2e-14	56.9
WP_013773975.1\|848349_848592_+	DUF896 family protein	NA	NA	NA	NA
WP_013773976.1\|848687_850682_+	transketolase	NA	NA	NA	NA
WP_013773977.1\|850902_852252_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_013773978.1\|852486_853116_+	membrane protein	NA	NA	NA	NA
WP_013773979.1\|853728_854679_+	LCP family protein	NA	NA	NA	NA
WP_013773980.1\|854659_855835_+	FtsW/RodA/SpoVE family cell cycle protein	NA	NA	NA	NA
WP_048589809.1\|855831_857052_+	FtsW/RodA/SpoVE family cell cycle protein	NA	NA	NA	NA
WP_013773982.1\|857633_858191_-	LysM peptidoglycan-binding domain-containing protein	A0A096XT26	Enterococcus_phage	4.4e-32	45.3
WP_013773983.1\|858767_859427_+	hypothetical protein	NA	NA	NA	NA
WP_013773984.1\|859573_861028_-	YfcC family protein	NA	NA	NA	NA
WP_013773985.1\|861239_862202_-	carbamate kinase	NA	NA	NA	NA
WP_013773986.1\|862224_863247_-	ornithine carbamoyltransferase	M1I6M4	Paramecium_bursaria_Chlorella_virus	1.8e-15	25.0
WP_013773987.1\|863268_864492_-	arginine deiminase	NA	NA	NA	NA
WP_048589820.1\|865109_867149_-	PTS transporter subunit EIIC	NA	NA	NA	NA
WP_013773989.1\|867179_868019_-	PRD domain-containing protein	NA	NA	NA	NA
WP_013773990.1\|868865_869207_+	metal-sulfur cluster assembly factor	NA	NA	NA	NA
WP_048589821.1\|869487_869829_-	hypothetical protein	NA	NA	NA	NA
WP_048589822.1\|871055_871517_-	hypothetical protein	NA	NA	NA	NA
WP_048589823.1\|871506_872184_-	hypothetical protein	NA	NA	NA	NA
WP_048589824.1\|872884_873241_-	DUF2335 domain-containing protein	S5WJ01	Leptospira_phage	5.0e-05	33.7
WP_048589825.1\|873317_873557_-	hypothetical protein	NA	NA	NA	NA
WP_048589826.1\|873920_874556_-	hypothetical protein	NA	NA	NA	NA
WP_048589827.1\|875309_876290_-	hypothetical protein	F0PIJ7	Enterococcus_phage	3.7e-50	48.6
WP_048589828.1\|876315_876513_-\|holin	holin	A0A1P8BL51	Lactococcus_phage	1.5e-11	44.4
WP_048589829.1\|876527_876734_-	hypothetical protein	A0A0S2MYG0	Enterococcus_phage	1.0e-13	56.1
WP_048589830.1\|876772_876919_-	XkdX family protein	A0A2H4J2R9	uncultured_Caudovirales_phage	6.4e-07	51.2
WP_048589831.1\|876908_877241_-	hypothetical protein	NA	NA	NA	NA
WP_048589832.1\|877255_877717_-	hypothetical protein	NA	NA	NA	NA
WP_127515677.1\|877716_878217_-\|plate	BppU family phage baseplate upper protein	A0A1J0MFQ3	Staphylococcus_phage	2.3e-19	37.7
WP_127515678.1\|878238_878406_-\|plate	BppU family phage baseplate upper protein	Q4ZE15	Staphylococcus_virus	2.5e-07	46.2
WP_048589833.1\|878395_878644_-	hypothetical protein	NA	NA	NA	NA
WP_048589834.1\|878627_878837_-	hypothetical protein	NA	NA	NA	NA
WP_048589835.1\|878823_880002_-	hypothetical protein	A0A0M7RDS2	Lactobacillus_phage	3.3e-37	28.8
WP_160171416.1\|880014_880767_-\|tail	phage tail family protein	A0A060AFE1	Staphylococcus_phage	2.1e-21	31.8
WP_048589837.1\|880850_882476_-	transglycosylase SLT domain-containing protein	Q8LTK2	Lactococcus_phage	1.4e-78	49.1
WP_048593187.1\|882498_885891_-	hypothetical protein	E9LUR1	Lactobacillus_phage	6.6e-94	42.4
WP_048589839.1\|885907_886108_-	hypothetical protein	NA	NA	NA	NA
WP_048589840.1\|886113_886443_-	hypothetical protein	NA	NA	NA	NA
WP_053078824.1\|886454_886742_-	collagen-like protein	NA	NA	NA	NA
WP_048589841.1\|886758_887379_-	hypothetical protein	NA	NA	NA	NA
WP_048589842.1\|887378_887765_-	hypothetical protein	NA	NA	NA	NA
WP_048589843.1\|887754_888183_-	hypothetical protein	A0A0M7RDL2	Lactobacillus_phage	1.9e-06	29.5
WP_048589844.1\|888175_888520_-\|head,tail	head-tail adaptor protein	NA	NA	NA	NA
WP_048589845.1\|888479_888881_-\|head,tail	phage gp6-like head-tail connector protein	E9LUQ4	Lactobacillus_phage	1.1e-16	50.0
888556:888590	attL	NA	NA	NA	NA
WP_053078825.1\|888916_890074_-\|capsid	phage major capsid protein	U3PBL1	Staphylococcus_phage	1.2e-66	47.7
WP_080719101.1\|890076_890682_-\|head,protease	HK97 family phage prohead protease	A0A0M4R4P2	Enterococcus_phage	4.0e-34	45.1
WP_048589846.1\|890575_891799_-\|portal	phage portal protein	E3W8F3	Leuconostoc_phage	3.1e-46	35.0
WP_048589847.1\|891801_892002_-	hypothetical protein	NA	NA	NA	NA
WP_053078826.1\|892002_893463_-\|terminase	terminase large subunit	Q9XJ75	Streptococcus_virus	3.3e-127	48.3
WP_053078827.1\|893508_893826_-	hypothetical protein	A0A286QRG1	Streptococcus_phage	1.2e-26	56.1
WP_048589848.1\|893822_894290_-\|terminase	phage terminase small subunit P27 family	E3W8E9	Leuconostoc_phage	1.7e-08	31.8
WP_160171417.1\|894342_894867_-	HNH endonuclease	Q9AZT3	Lactococcus_phage	3.2e-24	39.5
WP_155522195.1\|894992_895166_-	hypothetical protein	NA	NA	NA	NA
WP_048589850.1\|895879_896569_-	hypothetical protein	NA	NA	NA	NA
WP_013774291.1\|896882_897302_-	transcriptional regulator	E9LUP5	Lactobacillus_phage	1.8e-22	46.0
WP_013774292.1\|897315_897582_-	hypothetical protein	A0A249XZT5	Enterococcus_phage	2.8e-24	61.6
WP_013774293.1\|897571_897958_-	hypothetical protein	NA	NA	NA	NA
WP_013774294.1\|897958_898159_-	hypothetical protein	NA	NA	NA	NA
WP_048589851.1\|898385_898802_-	RusA family crossover junction endodeoxyribonuclease	S6B1L9	Thermus_phage	5.7e-32	53.8
WP_048589852.1\|898820_899318_-	single-stranded DNA-binding protein	A0A2I2MUI5	uncultured_Caudovirales_phage	3.8e-43	74.8
WP_048589853.1\|899314_899875_-	hypothetical protein	NA	NA	NA	NA
WP_048589854.1\|899892_900750_-	hypothetical protein	A0A2H4J2I9	uncultured_Caudovirales_phage	8.9e-32	54.5
WP_048589855.1\|900753_901440_-	hypothetical protein	C9E2N1	Enterococcus_phage	3.9e-86	65.6
WP_053078828.1\|901429_902044_-	ERF family protein	Q6JM07	Lactococcus_phage	7.3e-44	68.5
WP_048589857.1\|902073_902544_-	siphovirus Gp157 family protein	A0A1J0MFN6	Staphylococcus_phage	9.2e-31	46.0
WP_127515679.1\|902543_902849_-	hypothetical protein	NA	NA	NA	NA
WP_048589859.1\|902993_903437_+	hypothetical protein	NA	NA	NA	NA
WP_048589860.1\|903404_903638_-	hypothetical protein	NA	NA	NA	NA
WP_155522196.1\|903691_903832_-	hypothetical protein	NA	NA	NA	NA
WP_162836836.1\|903838_903976_-	hypothetical protein	NA	NA	NA	NA
WP_048589861.1\|904009_904285_-	hypothetical protein	NA	NA	NA	NA
WP_048589862.1\|904379_904883_+	hypothetical protein	NA	NA	NA	NA
WP_048589864.1\|905069_905594_-	hypothetical protein	A0A0S2MYI3	Enterococcus_phage	1.6e-20	45.4
WP_048589865.1\|905674_906013_+	hypothetical protein	NA	NA	NA	NA
WP_048589866.1\|906002_906197_-	hypothetical protein	NA	NA	NA	NA
WP_048589867.1\|906331_906577_-	hypothetical protein	NA	NA	NA	NA
WP_048589868.1\|906588_907344_-	antirepressor	L0P8P6	Lactobacillus_phage	8.0e-77	57.0
WP_127515680.1\|907380_907599_-	XRE family transcriptional regulator	NA	NA	NA	NA
WP_048589900.1\|907722_908490_+	helix-turn-helix transcriptional regulator	Q9G039	Staphylococcus_virus	2.8e-37	39.8
WP_048589870.1\|908594_909341_+	hypothetical protein	NA	NA	NA	NA
WP_064429785.1\|909430_909799_-	DUF2829 domain-containing protein	NA	NA	NA	NA
WP_048589871.1\|909846_910596_-	Rha family transcriptional regulator	A0A0K2CZD5	Paenibacillus_phage	5.8e-43	40.7
WP_162836837.1\|910619_910793_-	hypothetical protein	D7RWL9	Brochothrix_phage	4.2e-05	43.9
WP_048589872.1\|910983_911190_-	transcriptional regulator	NA	NA	NA	NA
WP_048589873.1\|911286_911769_+	helix-turn-helix transcriptional regulator	Q9AZH9	Lactococcus_phage	3.2e-10	31.6
WP_048589874.1\|911930_913076_+\|integrase	site-specific integrase	A0A1S5S7K9	Streptococcus_phage	1.7e-70	38.7
WP_013773992.1\|914366_914996_-\|bacteriocin	putative bacteriocin export ABC transporter	G9BWD6	Planktothrix_phage	9.8e-20	32.7
WP_041363481.1\|914998_915403_-	DUF1430 domain-containing protein	NA	NA	NA	NA
WP_048589875.1\|915399_916719_-	hypothetical protein	NA	NA	NA	NA
WP_015694914.1\|916832_917039_-	hypothetical protein	NA	NA	NA	NA
WP_048589876.1\|918169_919510_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_013773999.1\|919687_920626_-	DUF1803 domain-containing protein	NA	NA	NA	NA
WP_013774000.1\|920879_921806_-	manganese-dependent inorganic pyrophosphatase	NA	NA	NA	NA
WP_013774001.1\|921897_922662_-	pyruvate formate lyase-activating protein	A0A2P0VNQ0	Tetraselmis_virus	6.5e-26	30.6
WP_048589877.1\|922800_925047_-	formate C-acetyltransferase	A0A2P0VNR5	Tetraselmis_virus	2.5e-166	41.4
WP_013774003.1\|925258_927700_-	DNA topoisomerase IV subunit A	G3M9Z5	Bacillus_virus	4.6e-97	33.3
WP_013774004.1\|927711_929772_-	DNA topoisomerase IV subunit B	G3M9Z3	Bacillus_virus	1.1e-115	40.6
WP_013774005.1\|930105_930735_+	glycerol-3-phosphate 1-O-acyltransferase PlsY	NA	NA	NA	NA
WP_013774006.1\|930933_931809_-	aldose 1-epimerase family protein	NA	NA	NA	NA
WP_048589878.1\|931823_932612_-	GTP-sensing pleiotropic transcriptional regulator CodY	NA	NA	NA	NA
WP_041363545.1\|932629_934036_-\|protease	ATP-dependent protease ATPase subunit HslU	A0A173GFL6	Erwinia_phage	4.6e-41	27.2
WP_013774008.1\|934051_934600_-\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_013774009.1\|934635_935535_-	tyrosine recombinase XerC	S5W9T9	Leptospira_phage	1.3e-20	28.5
WP_013774010.1\|935727_937038_-\|tRNA	FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO	NA	NA	NA	NA
944834:944868	attR	NA	NA	NA	NA

DBSCAN-SWA_3

1194984 : 1244558

Streptococcus_phage(31.25%)

capsid,plate,tail,holin,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013774238.1\|1194984_1196751_-\|tRNA	aspartate--tRNA ligase	A0A1V0SAC0	Catovirus	3.1e-10	24.3
WP_048589935.1\|1196776_1198066_-\|tRNA	histidine--tRNA ligase	NA	NA	NA	NA
WP_013774240.1\|1198584_1199865_-	ABC transporter permease	NA	NA	NA	NA
WP_013774241.1\|1200918_1201851_+	aldo/keto reductase	NA	NA	NA	NA
WP_013774242.1\|1201991_1202441_-\|tRNA	D-tyrosyl-tRNA(Tyr) deacylase	NA	NA	NA	NA
WP_048590194.1\|1202457_1204677_-	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	A0A142EZT7	Stenotrophomonas_phage	9.5e-09	38.8
WP_013774246.1\|1205650_1206598_-	50S ribosomal protein L11 methyltransferase	NA	NA	NA	NA
WP_013774248.1\|1207032_1207737_-	DNA-3-methyladenine glycosylase	NA	NA	NA	NA
WP_013774249.1\|1207860_1209141_+	replication-associated recombination protein A	A0A127AWE7	Bacillus_phage	1.8e-105	49.4
WP_013774250.1\|1209524_1209803_+	hypothetical protein	NA	NA	NA	NA
WP_013774251.1\|1209898_1210399_+	universal stress protein	NA	NA	NA	NA
WP_013774252.1\|1211136_1212330_-	acetate kinase	NA	NA	NA	NA
WP_048589937.1\|1213645_1213909_-	hypothetical protein	NA	NA	NA	NA
WP_053078829.1\|1213981_1214422_-	prepilin-type N-terminal cleavage/methylation domain-containing protein	NA	NA	NA	NA
WP_041363232.1\|1214402_1214747_-	hypothetical protein	NA	NA	NA	NA
WP_013774256.1\|1214763_1215168_-	type II secretion system protein	NA	NA	NA	NA
WP_015694726.1\|1215164_1215440_-	prepilin-type N-terminal cleavage/methylation domain-containing protein	NA	NA	NA	NA
WP_013774318.1\|1215436_1216465_-	late competence protein ComGB, access of DNA to ComEA	NA	NA	NA	NA
WP_013774319.1\|1216418_1217399_-	Flp pilus assembly complex ATPase component TadA	NA	NA	NA	NA
WP_048589938.1\|1217938_1218892_-	metal ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_127515687.1\|1218888_1219731_-	metal ABC transporter permease	NA	NA	NA	NA
WP_013774325.1\|1220778_1221903_-	LCP family protein	A0A1X9I5X1	Streptococcus_phage	2.6e-23	33.5
WP_013774326.1\|1222462_1224298_-	elongation factor 4	E4ZFJ7	Streptococcus_phage	3.8e-19	24.6
WP_013774327.1\|1224473_1225691_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_013774328.1\|1225764_1226007_+	hypothetical protein	NA	NA	NA	NA
WP_013774329.1\|1226236_1227751_-	MFS transporter	NA	NA	NA	NA
WP_048589941.1\|1228568_1229642_-	mannonate dehydratase	NA	NA	NA	NA
WP_013774331.1\|1229625_1231269_-	mannitol dehydrogenase family protein	NA	NA	NA	NA
WP_013774332.1\|1232000_1232867_-	YitT family protein	M1Q1P6	Streptococcus_phage	1.8e-32	33.5
WP_126347290.1\|1233580_1234345_-\|holin	holin	A0A1S5S9Z7	Streptococcus_phage	2.7e-40	51.1
WP_013774334.1\|1234410_1234605_-\|holin	holin	A0A1P8BL51	Lactococcus_phage	1.2e-05	35.5
WP_013774335.1\|1234619_1234826_-	hypothetical protein	A0A0S2MYG0	Enterococcus_phage	2.6e-14	59.1
WP_127515688.1\|1235169_1235484_-	hypothetical protein	NA	NA	NA	NA
WP_013774337.1\|1235500_1235716_-	hypothetical protein	NA	NA	NA	NA
WP_013774338.1\|1235715_1235958_-	hypothetical protein	NA	NA	NA	NA
WP_013774339.1\|1235960_1236578_-	hypothetical protein	NA	NA	NA	NA
WP_048589943.1\|1236570_1237545_-\|plate	phage baseplate upper protein	Q9AZX4	Lactococcus_phage	4.4e-35	35.3
WP_013774343.1\|1240239_1240998_-	hypothetical protein	D7RWD9	Brochothrix_phage	2.4e-52	42.5
WP_013774344.1\|1241012_1242896_-\|tail	tail protein	A0A1L2JXP6	Streptococcus_phage	9.2e-21	29.2
WP_041363491.1\|1242911_1243235_-	hypothetical protein	A0A1P8BLR3	Lactococcus_phage	3.2e-22	52.9
WP_013774346.1\|1243252_1243600_-	hypothetical protein	Q77RZ7	Lactococcus_phage	2.1e-24	51.0
WP_048589944.1\|1243640_1244156_-\|tail	phage major tail protein, TP901-1 family	D7RWD5	Brochothrix_phage	6.1e-52	59.5
WP_127515689.1\|1244156_1244558_-\|capsid	phage capsid protein	C9E2J9	Enterococcus_phage	2.4e-27	49.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_AP021886

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_AP021886_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP021886_1

72785-72868

Orphan

Consensus_repeat	Method
CAAACACACAACAAAGAATTTTAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP021886_1

>merge|NZ_AP021886|1|72785-72868|CRISPRCasFinder
CAAACACACAACAAAGAATTTTATGAAGAAAACGGAAAAAAGGGCGGAGAGAAAACCGCCCAAACACATAACAAAGAATTTTAT

>NZ_AP021886|1|1|72785-72868|CRISPRCasFinder
CAAACACACAACAAAGAATTTTAT	GAAGAAAACGGAAAAAAGGGCGGAGAGAAAACCGCC
CAAACACATAACAAAGAATTTTAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP021886.1\|WP_048590023.1\|82702_83374_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
NZ_AP021886.1\|WP_013774774.1\|59546_60818_+\|serine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235461
NZ_AP021886.1\|WP_013774774.1\|56810_58082_-\|serine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235461
NZ_AP021886.1\|WP_013774752.1\|89157_90078_-\|DUF979-domain-containing-protein	unknown	unknown	gnl\|CDD\|377620
NZ_AP021886.1\|WP_013774755.1\|86958_87375_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP021886.1\|WP_048590027.1\|61228_62257_+\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|379113
NZ_AP021886.1\|WP_013774753.1\|88475_89123_-\|pyroglutamyl-peptidase-I	unknown	unknown	gnl\|CDD\|237299
NZ_AP021886.1\|WP_099046203.1\|77513_79715_-\|glycoside-hydrolase-family-2-protein	unknown	unknown	gnl\|CDD\|225789
NZ_AP021886.1\|WP_013774763.1\|77270_77504_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375991
NZ_AP021886.1\|WP_013774761.1\|80409_82716_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376899
NZ_AP021886.1\|WP_013774765.1\|73784_74354_+\|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|212030
NZ_AP021886.1\|WP_013774757.1\|84786_85470_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213222
NZ_AP021886.1\|WP_013774769.1\|67618_68161_-\|phenolic-acid-decarboxylase	unknown	unknown	gnl\|CDD\|226010
NZ_AP021886.1\|WP_013774770.1\|64878_66987_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP021886.1\|WP_048590024.1\|74855_76268_-\|glucuronate-isomerase	unknown	unknown	gnl\|CDD\|376859
NZ_AP021886.1\|WP_013774767.1\|69638_70991_-\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224096
NZ_AP021886.1\|WP_099046202.1\|71138_72245_-\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|270373
NZ_AP021886.1\|WP_048590027.1\|55371_56400_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|379113
NZ_AP021886.1\|WP_013774772.1\|62284_62986_+\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta	unknown	unknown	gnl\|CDD\|129802
NZ_AP021886.1\|WP_014868598.1\|68793_69633_-\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226354

Protein	Function_ID	Function_description	E-value
NZ_AP021886.1\|WP_048590023.1\|82702_83374_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	2.70202e-87
NZ_AP021886.1\|WP_013774774.1\|59546_60818_+\|serine--tRNA-ligase	gnl\|CDD\|235461	PRK05431, PRK05431, seryl-tRNA synthetase; Provisional.	0
NZ_AP021886.1\|WP_013774774.1\|56810_58082_-\|serine--tRNA-ligase	gnl\|CDD\|235461	PRK05431, PRK05431, seryl-tRNA synthetase; Provisional.	0
NZ_AP021886.1\|WP_013774752.1\|89157_90078_-\|DUF979-domain-containing-protein	gnl\|CDD\|377620	pfam06166, DUF979, Protein of unknown function (DUF979). This family consists of several putative bacterial membrane proteins. The function of this family is unclear.	6.68446e-147
NZ_AP021886.1\|WP_048590024.1\|74855_76268_-\|glucuronate-isomerase	gnl\|CDD\|376859	pfam02614, UxaC, Glucuronate isomerase. This is a family of Glucuronate isomerases also known as D-glucuronate isomerase, uronic isomerase, uronate isomerase, or uronic acid isomerase, EC:5.3.1.12. This enzyme catalyzes the reactions: D-glucuronate <=> D-fructuronate and D-galacturonate <=> D-tagaturonate. It is not however clear where the experimental evidence for this functional assignment came from and thus this family has no literature reference.	0
NZ_AP021886.1\|WP_013774753.1\|88475_89123_-\|pyroglutamyl-peptidase-I	gnl\|CDD\|237299	PRK13197, PRK13197, pyrrolidone-carboxylate peptidase; Provisional.	4.1714e-123
NZ_AP021886.1\|WP_099046203.1\|77513_79715_-\|glycoside-hydrolase-family-2-protein	gnl\|CDD\|225789	COG3250, LacZ, Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].	3.4064e-58
NZ_AP021886.1\|WP_013774763.1\|77270_77504_-\|hypothetical-protein	gnl\|CDD\|375991	pfam18565, Glyco_hydro2_C5, Glycoside hydrolase family 2 C-terminal domain 5. Domain 5 is found in dimeric beta-D-galactosidase from Paracoccus sp. 32d, which contributes to stabilization of the functional dimer. It is suggested that the location of this domain 5, may be one of the factors responsible for the creation of a functional dimer and cold-adaptation of this enzyme.	4.36621e-10
NZ_AP021886.1\|WP_013774761.1\|80409_82716_-\|ABC-transporter-permease	gnl\|CDD\|376899	pfam02687, FtsX, FtsX-like permease family. This is a family of predicted permeases and hypothetical transmembrane proteins. Buchnera aphidicola LolC has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both LolC and Streptococcus cristatus TptD have been shown to require ATP. This region contains three transmembrane helices.	0.00901662
NZ_AP021886.1\|WP_013774765.1\|73784_74354_+\|LysM-peptidoglycan-binding-domain-containing-protein	gnl\|CDD\|212030	cd00118, LysM, Lysin Motif is a small domain involved in binding peptidoglycan. LysM, a small globular domain with approximately 40 amino acids, is a widespread protein module involved in binding peptidoglycan in bacteria and chitin in eukaryotes. The domain was originally identified in enzymes that degrade bacterial cell walls, but proteins involved in many other biological functions also contain this domain. It has been reported that the LysM domain functions as a signal for specific plant-bacteria recognition in bacterial pathogenesis. Many of these enzymes are modular and are composed of catalytic units linked to one or several repeats of LysM domains. LysM domains are found in bacteria and eukaryotes.	6.13602e-11
NZ_AP021886.1\|WP_013774757.1\|84786_85470_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	1.39125e-73
NZ_AP021886.1\|WP_013774769.1\|67618_68161_-\|phenolic-acid-decarboxylase	gnl\|CDD\|226010	COG3479, COG3479, Phenolic acid decarboxylase [Secondary metabolites biosynthesis, transport, and catabolism].	1.96605e-100
NZ_AP021886.1\|WP_048590027.1\|61228_62257_+\|transcriptional-regulator	gnl\|CDD\|379113	pfam13303, PTS_EIIC_2, Phosphotransferase system, EIIC. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. The sugar-specific permease of the PTS consists of three domains (IIA, IIB and IIC). The IIC domain catalyzes the transfer of a phosphoryl group from IIB to the sugar substrate.	3.48497e-48
NZ_AP021886.1\|WP_013774767.1\|69638_70991_-\|sugar-ABC-transporter-permease	gnl\|CDD\|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	4.03668e-57
NZ_AP021886.1\|WP_099046202.1\|71138_72245_-\|extracellular-solute-binding-protein	gnl\|CDD\|270373	cd13655, PBP2_oligosaccharide_1, The periplasmic binding component of ABC tansport system specific for an unknown oligosaccharide; possess the type 2 periplasmic binidng fold. This group represents an uncharacterized periplasmic-binding protein of an ATP-binding cassette transporter predicted to be involved in uptake of an unknown oligosaccharide molecule. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.56013e-150
NZ_AP021886.1\|WP_048590027.1\|55371_56400_-\|transcriptional-regulator	gnl\|CDD\|379113	pfam13303, PTS_EIIC_2, Phosphotransferase system, EIIC. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. The sugar-specific permease of the PTS consists of three domains (IIA, IIB and IIC). The IIC domain catalyzes the transfer of a phosphoryl group from IIB to the sugar substrate.	3.48497e-48
NZ_AP021886.1\|WP_013774772.1\|62284_62986_+\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta	gnl\|CDD\|129802	TIGR00719, Probable_L-serine_dehydratase_beta_chain, L-serine dehydratase, iron-sulfur-dependent, beta subunit. This enzyme is also called serine deaminase. This model describes the beta chain of an iron-sulfur-dependent L-serine dehydratase, as in Bacillus subtilis. A fairly deep split in a UPGMA tree separates members of this family of beta chains from the homologous region of single chain forms such as found in E. coli. This family of enzymes is not homologous to the pyridoxal phosphate-dependent threonine deaminases and eukaryotic serine deaminases. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	1.05911e-46
NZ_AP021886.1\|WP_014868598.1\|68793_69633_-\|sugar-ABC-transporter-permease	gnl\|CDD\|226354	COG3833, MalG, ABC-type maltose transport systems, permease component [Carbohydrate transport and metabolism].	1.27529e-95

>NZ_AP021886.1|WP_099046202.1|71138_72245_-|extracellular-solute-binding-protein
MEEIKPTGGKEKKGTIKLWVDAAVIDIYKPIVKQFENEHKGLKIIVKPSETGKAQENVKKDPSAAADVFMMPHDQLGQLVGAGTIYPNTKYANNVKKNNAKNLVDSATYNGKLYGYPYGMETLIAYYNKSKLTAEEMKTWETITKNGKLGTNFSEENANYVFVPLFMSNGDELYGKTGENIKGTNFNNEKGVQVLNWIYDQKDNKGVVQSNDDALSRLRNGEIDAFLSGPWSKNDAKKALGKNFAVTSYPTVNFGNGEVQQKAFLGVKLFCVNASTKNPLASMALADYLTKKENQLTVFEKNGIVPSNKEVLEQSNVQSDAVVHAVMTMSNEEHSVTMPKLPEMVSFWEPADALINDTYNHKISKNQF
>NZ_AP021886.1|WP_013774767.1|69638_70991_-|sugar-ABC-transporter-permease
MRKNNQTNQLSFWRVFKTGDLPIKASYLIMGSTNFANKQKIKGLLFLLLQISFIAWFIFYGFQALKMLQTLGTKAQSWVMDDSLGIEVQEAGDNSMLLLLFGIVAIMICMAFVVLYIVNLRSTRKIFQLKKAGKKIPNLREDLSSLLNENFYITLISLPFLGVLLFTVLPLVYMTSIAFTSYDHNHLPSKNLFHCVGFSNFNEMIHGDIAGTFFPIFIWTIVWAILATITTFFFGILLALLINTKGIKGKKVWRTIFVITMAVPQFVSLLIMANLFNNSGPINTLLQKWQWITQPIPFLTNGIMAKITIIIVNMWVGIPVTMLVTTSILTNLPKDQIEAAELDGATKVQIFKKITFPQILFVMFPSLIQQFIININNFNVIFLLTGGQPANSNYYSAGETDLLVTWLYKLTVTVADYNLASVIGIIIFILSATFSLLAYTRSNSFKTEGV
>NZ_AP021886.1|WP_014868598.1|68793_69633_-|sugar-ABC-transporter-permease
MKTTKKTGLIFCYGLLTLLAIVWLFPIVWIIVTSFREEGGTFVTYFIPKQWTIKNYQLLLTSSTYPFVQWFINTLIVASFSCLISTLSTIAIAYSLSRLRFKMRKSFLKIALVLNMFPGFMSMIAVYYILKAMNLTGSLFALILVYSSASALAFYIAKGFFDTIPKTLDESAMMDGANRYQIFISITLPLSKPMIVYTALTTFMIPWMDFIFAKIILGDNVNKYTVAIGLFTMQTKDNMNKYFMAFTAGCVLIAVPITLLFIFIQKYYVEGITSGSVKE
>NZ_AP021886.1|WP_013774769.1|67618_68161_-|phenolic-acid-decarboxylase
MSKKIFKTLSDFLGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMVAGRWVTDQQADIVMLTEGIYKVAWTEPTGTDVVLDFVPNENKLNGTIFFPKWVQDHPEITVTYQNEHIDLMEESREKYETYPKLMVPEFATITYIGNAGLNNDDVISEAPYKELPDDIRNGRYFDQEYKRINRC
>NZ_AP021886.1|WP_013774770.1|64878_66987_-|hypothetical-protein
MKNKLLIIFVPLTCFIFCFFMINIQESYADPITQLPNFQYSGTMLPESKDIFNFRYGKNTYFKKLSGEVLNGEKLYVNKTPSEAQAMIYHIGYYQGKNINVKITLTGRAGGLYINKKDFLNIDLDIGGWITIKFEFFDQANNPVSIPLTTNWNKINKQVSLKIGKDKIRYLIADPTNQFTYKEESNGELTLQNNVTSAVDTGINSSLQCILYPTTEVSFNFNHKQGYNSYIKYNYENLNASMLSNAYGLDERFDTFNSNDLTLTAVQDISNNIADESNASNGKLNALATNFRKEIDSLPFSQYKIDGFQVLDSDGNNLTDLFSLSVKDENDIILIARNPKDNRLYNTALMYLVKSKWIGSEEKPVDPGRIDNNGYLKVPFEVQTTSIPNNTFISKGQSSIFYKGNININFVDIDNPEKILRDPLTIPSILTLSFDLSKEYPDIPNYQPVFTPSNDSENNDKGILLEKTKEITHQYLRKNNIHFEILNKDSLTINQGTQTEVTMNFSVSLELSDAYDLYGEYNGKRQLIHHYTTSNGKKDSLTFNIPKEWIGKKVIFYVVSNHYNTESNKEERQIIAREPELRVPPIFSFGETEIKNEKYGILLPDALKNEIKVIDDAQVKWKINIKEMLPFSAKNEEQLLERIHFTIKGKEYILNQEDQTILTGETSTQLDKNDSIFIIITPADKPGKYQGILEWTLLNGPS
>NZ_AP021886.1|WP_013774772.1|62284_62986_+|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta
MVENIKNSRKKQKVLNYKSCFDIIGPIMIGPSSSHTAGAVSIGQVARKLFGKTPKKIICKYYESFAETHKGHGTDYAIIAGILGFATNDSRVPQAIELAESEGISIEFIEMEGDSSVHHANTACLYLEDDTHSIHVTGISLGGGTIEIKYIEIDGFIIEPQGTLPILLTLTKNENTKIGIENILKENNIKINKIVKLENDQDYLYEFDLDSRPLPAIANELVNFDKETRIILL
>NZ_AP021886.1|WP_048590027.1|61228_62257_+|transcriptional-regulator
MKILLGVGMLLLVILVMFLFAFYAPNGRKALSALSGAACSTFLPEAFLHYAIGDVFHIQYVAKIGETMGGLGGLAAGTLVPLAFGISPVFSVIMGVSLINFKLLPAFVAAYLLSFVLKQLQKYIPEGIDLIVIILVIPLSTYFVADIIQPFVMGILQIIGNSILSAIGANPYFMGALLGVIIPIVGMTPLSSMVLTALIGLTGVPMAIGALGCFGNSILNFMLFNRLPFGDKSTALAVTIEPLTQIDIISSNPIPIFGTNAVAGAINGMIVTYFGLKVPVTGMATPWAGLLVVLGNNPINKALITVACIVICSLVIGFIGSIVFKNFKLVTVNDLRKDTQIS
>NZ_AP021886.1|WP_013774774.1|59546_60818_+|serine--tRNA-ligase
MLDIKKIRKNYDNLIVLFEQRGVEKSTIDHLLELDQTRRNILPKLEEQKQLRNKLSDEVAELKKSNQSSEENIENIRKINKNIKELAGELSLTEKQYTDILVNLPNLPDETVPFVQDEDDNIEVKRWSKPRQFDFHPKAHYEIGEALDILDFQRGAKVTGARFLYYKNLGARLERAIYNFMLDTHINEHGFQEMITPYMVNSKSMFGTGQFPKFKEDVFQVADTDYTLIPTAEVPLTNYYANEILSEDELPIYFTAMSPCFRSEAGSAGKDTRGLIRLHQFHKVEMVKFTTEETSYDELESLTRAGEEILEKLELPYRTIVLCTGDMGFSAAKTYDIEVWMPAQNTYREISSCSNCVDFQARRAMIRYRTKDGEIKYAHTLNGSGLAVGRTVAAIIENYQNEDGSVTIPEVLQPYMGGQSVLK
>NZ_AP021886.1|WP_013774774.1|56810_58082_-|serine--tRNA-ligase
MLDIKKIRKNYDNLIVLFEQRGVEKSTIDHLLELDQTRRNILPKLEEQKQLRNKLSDEVAELKKSNQSSEENIENIRKINKNIKELAGELSLTEKQYTDILVNLPNLPDETVPFVQDEDDNIEVKRWSKPRQFDFHPKAHYEIGEALDILDFQRGAKVTGARFLYYKNLGARLERAIYNFMLDTHINEHGFQEMITPYMVNSKSMFGTGQFPKFKEDVFQVADTDYTLIPTAEVPLTNYYANEILSEDELPIYFTAMSPCFRSEAGSAGKDTRGLIRLHQFHKVEMVKFTTEETSYDELESLTRAGEEILEKLELPYRTIVLCTGDMGFSAAKTYDIEVWMPAQNTYREISSCSNCVDFQARRAMIRYRTKDGEIKYAHTLNGSGLAVGRTVAAIIENYQNEDGSVTIPEVLQPYMGGQSVLK
>NZ_AP021886.1|WP_048590027.1|55371_56400_-|transcriptional-regulator
MKILLGVGMLLLVILVMFLFAFYAPNGRKALSALSGAACSTFLPEAFLHYAIGDVFHIQYVAKIGETMGGLGGLAAGTLVPLAFGISPVFSVIMGVSLINFKLLPAFVAAYLLSFVLKQLQKYIPEGIDLIVIILVIPLSTYFVADIIQPFVMGILQIIGNSILSAIGANPYFMGALLGVIIPIVGMTPLSSMVLTALIGLTGVPMAIGALGCFGNSILNFMLFNRLPFGDKSTALAVTIEPLTQIDIISSNPIPIFGTNAVAGAINGMIVTYFGLKVPVTGMATPWAGLLVVLGNNPINKALITVACIVICSLVIGFIGSIVFKNFKLVTVNDLRKDTQIS
>NZ_AP021886.1|WP_013774765.1|73784_74354_+|LysM-peptidoglycan-binding-domain-containing-protein
MKSLKTILLGTTLAAGIGLSLGAGNVHADSLYKVQAGDTLSSIAAKNHTNIQEVANKNQISNINMIYEGQQLQIKTADSAVATPKTMQATPIAQPALSTTPMIQKQAPAQTSAPTSDSNSAKEWIAQRESSGSYNATNGKYIGRYQLDASYLKGDYSPANQEKVAENYVSERYGSWEQAKTFWMNNGWY
>NZ_AP021886.1|WP_048590024.1|74855_76268_-|glucuronate-isomerase
MFLDEDFLLTTPMAKKLFHDYAAEMPIIDYHCHLDPKEIYEDKNFNNITEAWLTEGNNFGDHYKWRLMRANGVPEELITGNGDPYEKFLAFAGVLEKAYGNLIFEWCHLELRRFFGIEEVLTIETAPKIWEEANKKIVTETFSRRQLIRNMHVKALSTTDDPTDDLHYHELIKKEEATNGFKVIPGFRPDKILNIQVDTFTDYLEKLAKVSGVMIEQFSDIKKALEKRVEYFEEHGGNICDHGLDSVQYAEETEEELNEILAKRKARKQLTEIEIAKYRTGVLLSLMKIYTDHDWTVQFHMHALRNLNKIAFEKMGADVGFDAINDEQVAVMTGKLLNACNENGALPKLVLYSLNQNDWMQLLTVMGCFQGGRKQKMQFGTAWWFDDTRSGMRKQLKMLMEQSLLGNFIGMLTDSRSFLSYPRHEYFRRVLCELLGEMVERGQIPADEKRLGKMVQDISYNNAEEYFQFK
>NZ_AP021886.1|WP_013774763.1|77270_77504_-|hypothetical-protein
MNDDCDIVATITGSADLLAFGSGNPKPLTNFNTNKTRTFNGRALLILAKNQQLSSIQIAVHSNNDSKKDEIVGQLTI
>NZ_AP021886.1|WP_099046203.1|77513_79715_-|glycoside-hydrolase-family-2-protein
MQVKKFNQDWYYWKEQNSFALVWDIPEYAKIVQLPHDAMLEQAAYAESQNGGNTGYHDGAIYNYVKKLVVHENQKSEQFILKFEGIYMNAAVYVNGQLAGKNPFGYSTFYVTLNDYLKYGTENEIRVQARNGAMTNSRWYSGGGIYRDVYLLTSGSLFIEPTSIHIKTEQATKELASLSIKTKVINKENYYQDVQLITTVKTKSGEVVASTTDLFNLLSNDTRTFSQRLTVIHPELWSAETPTLYKCISQLYSNNQLIDEEVTTFGIRTLTLDSYHGLQVNHIPVKLRGACVHHDSGLLGAATYKETHLRQIAKLKAAGFNAIRMSHQPMAPAMLEACDELGMYVMDETFDMWNHCKSDYDYGLYFNEWWEKDVESMVLKDYNHPSVLLYSVGNEIPEIATNQGNKVCYELVEKIRSLDHTRYILASINGMFAVGDQLGEIIQDILPTQSADEETLDGNVNDFMTVLDIHLDEIVTHEIVGQALERVSGLLDITGYNYMTARYELDAKEHANRILVGSETYPPEIARNWEIIKKLPTVIGDFTWTGWDYLGEAGVGVPAYKWGEGGFGAAFPCQLAYVGDLDITGFRRPMSYYREIVFGLRTAPYLAIQNPYQPKEKLIKTPWIMSDTMSSWDWELPRGTLINVEVYAPGERIELWLNDTCVAQENMPEGSYRQIISIPYEPGKLCAYNYQGTKLLGQTELLTTGKATRIQLTPELMYSQELIYIEVCLVDEA
>NZ_AP021886.1|WP_013774761.1|80409_82716_-|ABC-transporter-permease
MKNYKTWKIFLNGFILSFVVIFICIALFQVGTNINKDLDNHNKITLKAINKTPYRDIKSLTDKYPGNVVITADGFAKLNKKGYEEYLLMKKSNNFSKYVLMEGRKPKSAAELIISKRNADQNHIKLNKKINVDSRGKRVVGIFKNEGDINEDVVERIKLKEETVISNLEFTNLKKTDYTFIKKNKTANFEVEANDGNNKKETLLILLQLIVYITFIITIFFLLIMMEYEIKKILIRRKKNIFLLKSMGETNRNILYYELSYFLKPLIIGLIFGVLIGTAIIPLAYNALLGNFGGENFYQFTYNNYPVIQIILGVLICFIVETVLFYSNISKSLRSVSLKSFYMNKENNRYSFKHILLYLLVAILAVIAVSVMIQLSLISTTKIIISLILIMSILLLPQGVIKLINKIFPGKLLFAKSFLNSNQKKVSSIILVFTAILTLQFVVISATLSSLKSVNEGWKVILTGDGFGINPSGDKIDPQILDELKGIDHLYLSKRIYPTEKIRFKSQETNGFMVKGTDIDKYKDSVKGKISDGKILIGRAISVKLGIKPGDQIVFKNKKIEVSGVTSSGENGGDIVYMYPALFRELFGEKGADIATLNIVNQRSFEKSIRGKENVFYFRTNAEYIKTGINSVYTTLSPVIALCVIVALLGIAIIMLMLNDLIYDSRKAIVLLRSLGSGRLSLFKENLLVLCMLSFLAYLYALLFTQIISDTLNFFIASKLGSIVEINSFNLYTLLLSAVILFLMNLLIAVKNTFSMKKVSIAEEMRTL
>NZ_AP021886.1|WP_048590023.1|82702_83374_-|ABC-transporter-ATP-binding-protein
MIEVKNLEKKYEKRTILNDVSLEIISGKITVILGESGSGKSTLLNLLAGFDFDLPNVGEIFIENTNISKLNEEQRTKFRKGKIGFIFQDFMLFEDLTVEENLRMGAKFNLKDLNIVETNALIDETLELLGLIEKKKSYPEQLSGGQKQRVAIGRTLCTSPDFIFADEPTGALDSVNEEDILNIFSLINQKYETTLVLVTHSQRVAEAADEIIRIVDGKIYEEL
>NZ_AP021886.1|WP_013774757.1|84786_85470_-|ABC-transporter-ATP-binding-protein
MSIKVENLTYSIQEGNQARKILNNISINIPKGKLTSITGESGSGKTTLLYGLSGILKIDEGNVFLDDKNLYNMKIKEREKFRLNHISFIYQQLNLFNFLNVEENIKINWLLRNKKISKDVDKQIDQYLELFNLGNSKKKEIQSLSGGEKQRIAIIRSFVSKSDFIFTDEPTGNLDTKNSLLFMESLQKIMKNSTRTVIMVTHDSKLCNYADEKINLIDGKINNHTII
>NZ_AP021886.1|WP_013774755.1|86958_87375_-|hypothetical-protein
MKEIVKKLIKDNPVQNILYGVGSTLNLIVIGVFLMLVKELIKIKKNTALISRNEQISFYFSTLITISIIVIIFSVLVLCMIQKSVFHSRRDFNIKMKLTGISSICLAKIYIKEIFTIQKITIPLGILLMQLTYTIISR
>NZ_AP021886.1|WP_013774753.1|88475_89123_-|pyroglutamyl-peptidase-I
MKILVTGFDPFGGETTNPALDAVKGLPDKIREAEIIKLEIPTVFNKSAEVTKQAILTYQPDVVLNVGQAGGRFTVTPERVAINRDDARIPDNEGNQPINDSIHEDGAPAYFTQLPIKAMVKMIRDAGLPAAVSNTAGTFVCNHIMYQVQYMIDKEFPELKGGFIHVPFIASQVIDKPETPFMNLADIITSLEKSIEAILLFDEQKDLETIEGTIH
>NZ_AP021886.1|WP_013774752.1|89157_90078_-|DUF979-domain-containing-protein
MDKFIPTILEFFYILIGLLSILTSFRVFFDKTNSARIGTSLFWLLLGIIFAAGNFMPYAISGILLTIIGILTLFKQVKIGKLAELSEKDGEKSAKRIGNWVFFPSILLAALAVGISYTSLGGQVGIGIASILSLIVAMFIMRAKPKTMLDDTDRMLQSVGTTGILPQLLAALGVIFNTAGVGDVISHAVSGVVPEGNRLAGVIAYCLGMIIFTMVMGNGFAAFTVITAGIGIPFVISQGGDPVISGTLAMSAGFSGTLLTPMAANFNALPVALLEMKDSNGVIKAQAPIALIMIVVHIALMYFLAF

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Identity
NZ_AP021886_1	1.1\|72809\|36\|NZ_AP021886\|CRISPRCasFinder	72809-72844	36	NZ_CP006684	Melissococcus plutonius S1 plasmid pMEPL_178, complete sequence	72811-72846	1.0
NZ_AP021886_1	1.1\|72809\|36\|NZ_AP021886\|CRISPRCasFinder	72809-72844	36	NZ_AP021886	Melissococcus plutonius strain DAT1033 plasmid pMP1, complete sequence	72809-72844	1.0
NZ_AP021886_1	1.1\|72809\|36\|NZ_AP021886\|CRISPRCasFinder	72809-72844	36	NZ_AP018525	Melissococcus plutonius strain DAT585 plasmid pMP1, complete sequence	72911-72946	1.0
NZ_AP021886_1	1.1\|72809\|36\|NZ_AP021886\|CRISPRCasFinder	72809-72844	36	NC_018265	Melissococcus plutonius DAT561 plasmid 1, complete sequence	119626-119661	1.0

1. spacer 1.1|72809|36|NZ_AP021886|CRISPRCasFinder matches to NZ_CP006684 (Melissococcus plutonius S1 plasmid pMEPL_178, complete sequence) position: , mismatch: 0, identity: 1.0

gaagaaaacggaaaaaagggcggagagaaaaccgcc	CRISPR spacer
gaagaaaacggaaaaaagggcggagagaaaaccgcc	Protospacer
************************************

2. spacer 1.1|72809|36|NZ_AP021886|CRISPRCasFinder matches to NZ_AP021886 (Melissococcus plutonius strain DAT1033 plasmid pMP1, complete sequence) position: , mismatch: 0, identity: 1.0

gaagaaaacggaaaaaagggcggagagaaaaccgcc	CRISPR spacer
gaagaaaacggaaaaaagggcggagagaaaaccgcc	Protospacer
************************************

3. spacer 1.1|72809|36|NZ_AP021886|CRISPRCasFinder matches to NZ_AP018525 (Melissococcus plutonius strain DAT585 plasmid pMP1, complete sequence) position: , mismatch: 0, identity: 1.0

gaagaaaacggaaaaaagggcggagagaaaaccgcc	CRISPR spacer
gaagaaaacggaaaaaagggcggagagaaaaccgcc	Protospacer
************************************

4. spacer 1.1|72809|36|NZ_AP021886|CRISPRCasFinder matches to NC_018265 (Melissococcus plutonius DAT561 plasmid 1, complete sequence) position: , mismatch: 0, identity: 1.0

gaagaaaacggaaaaaagggcggagagaaaaccgcc	CRISPR spacer
gaagaaaacggaaaaaagggcggagagaaaaccgcc	Protospacer
************************************

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_AP021885

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_AP021886

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection