CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP018186	Streptococcus salivarius strain ICDC1 chromosome, complete genome	2 crisprs	DEDDh,csa3,cas9,cas1,cas2,csn2,DinG,WYL,cas3	0	10	11	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP018186_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018186_1

490018-490910

TypeII

II-A,II-B

Consensus_repeat	Method
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	PILER-CR
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	CRISPRCasFinder
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	CRT

13 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of NZ_CP018186_1

>merge|NZ_CP018186|1|490018-490910|PILER-CR,CRISPRCasFinder,CRT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAACACCAGCGGTAGTGATCTTAGCTTGTTCCGCGTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAACGCCGTAGATGGCACGTTCGATGGTCAACGGTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAACATGGTGGCAGTTTACTTCTACTGGTACTGCGTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAACATTATCCTAGCCTTTTTGTGTATTTGAAAAGTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAACAGTATTTGGTGGATATGCACTTACAGGAGCGTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAACAGCTATGTTAGTAAGTCTTTACGGTAAGTTGTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAACTGCACCAAGCATTGATAAACCAGAATGGTCGTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAACTAACTGTCTTGTGGTAGCGGATATTGTTTTGTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAACAAAATGGCAACGTGACTTACGGGCGTGGCAGTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAACCCTCTGTAAGAGGTTTACCGTCGAACATCAGTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAACTATTAAACGCTTCAATCGTCGAGGAGCTGAGTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAACGTGAAGTTGACCCAAAAGACTAAAGTCTAAGTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAACTGAACTAATTAAGACGATTGGAGAACACAAGTTTTAGAGCTGCCTTGTTTCGAATGGTTTCACTCT

>NZ_CP018186|1|1|490018-490844|PILER-CR
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	ACCAGCGGTAGTGATCTTAGCTTGTTCCGC
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	GCCGTAGATGGCACGTTCGATGGTCAACG
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	ATGGTGGCAGTTTACTTCTACTGGTACTGC
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	ATTATCCTAGCCTTTTTGTGTATTTGAAAA
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	AGTATTTGGTGGATATGCACTTACAGGAGC
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	AGCTATGTTAGTAAGTCTTTACGGTAAGTT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	TGCACCAAGCATTGATAAACCAGAATGGTC
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	TAACTGTCTTGTGGTAGCGGATATTGTTTT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	AAAATGGCAACGTGACTTACGGGCGTGGCA
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	CCTCTGTAAGAGGTTTACCGTCGAACATCA
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	TATTAAACGCTTCAATCGTCGAGGAGCTGA
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	GTGAAGTTGACCCAAAAGACTAAAGTCTAA
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC

>NZ_CP018186|1|1|490018-490910|CRISPRCasFinder
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	ACCAGCGGTAGTGATCTTAGCTTGTTCCGC
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	GCCGTAGATGGCACGTTCGATGGTCAACG
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	ATGGTGGCAGTTTACTTCTACTGGTACTGC
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	ATTATCCTAGCCTTTTTGTGTATTTGAAAA
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	AGTATTTGGTGGATATGCACTTACAGGAGC
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	AGCTATGTTAGTAAGTCTTTACGGTAAGTT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	TGCACCAAGCATTGATAAACCAGAATGGTC
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	TAACTGTCTTGTGGTAGCGGATATTGTTTT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	AAAATGGCAACGTGACTTACGGGCGTGGCA
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	CCTCTGTAAGAGGTTTACCGTCGAACATCA
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	TATTAAACGCTTCAATCGTCGAGGAGCTGA
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	GTGAAGTTGACCCAAAAGACTAAAGTCTAA
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	TGAACTAATTAAGACGATTGGAGAACACAA
GTTTTAGAGCTGCCTTGTTTCGAATGGTTTCACTCT

>NZ_CP018186|1|1|490018-490910|CRT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	ACCAGCGGTAGTGATCTTAGCTTGTTCCGC
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	GCCGTAGATGGCACGTTCGATGGTCAACG
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	ATGGTGGCAGTTTACTTCTACTGGTACTGC
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	ATTATCCTAGCCTTTTTGTGTATTTGAAAA
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	AGTATTTGGTGGATATGCACTTACAGGAGC
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	AGCTATGTTAGTAAGTCTTTACGGTAAGTT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	TGCACCAAGCATTGATAAACCAGAATGGTC
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	TAACTGTCTTGTGGTAGCGGATATTGTTTT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	AAAATGGCAACGTGACTTACGGGCGTGGCA
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	CCTCTGTAAGAGGTTTACCGTCGAACATCA
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	TATTAAACGCTTCAATCGTCGAGGAGCTGA
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	GTGAAGTTGACCCAAAAGACTAAAGTCTAA
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	TGAACTAATTAAGACGATTGGAGAACACAA
GTTTTAGAGCTGCCTTGTTTCGAATGGTTTCACTCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018186.1\|WP_045772201.1\|488703_489048_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_CP018186.1\|WP_045772202.1\|489037_489697_+\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd09758_csn2_CAS-II-A	gnl\|CDD\|213408
NZ_CP018186.1\|WP_045772208.1\|494717_495449_+\|rRNA-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|224108
NZ_CP018186.1\|WP_045772199.1\|483680_487838_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|273840
NZ_CP018186.1\|WP_045772207.1\|493742_494717_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226231
NZ_CP018186.1\|WP_045772197.1\|482151_482913_+\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NZ_CP018186.1\|WP_002886788.1\|479390_481115_+\|septation-ring-formation-regulator-EzrA	unknown	unknown	gnl\|CDD\|179877
NZ_CP018186.1\|WP_045772204.1\|491269_492160_-\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|223769
NZ_CP018186.1\|WP_002884694.1\|495753_497067_+\|GTPase-ObgE	unknown	unknown	gnl\|CDD\|237046
NZ_CP018186.1\|WP_045772194.1\|476780_477341_+\|HAD-IA-family-hydrolase	unknown	unknown	gnl\|CDD\|319825
NZ_CP018186.1\|WP_014634861.1\|490992_491232_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018186.1\|WP_045772200.1\|487837_488707_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NZ_CP018186.1\|WP_045772205.1\|492886_493252_+\|OsmC-family-protein	unknown	unknown	gnl\|CDD\|376823
NZ_CP018186.1\|WP_156209481.1\|482932_483319_+\|transposase	unknown	unknown	gnl\|CDD\|376773
NZ_CP018186.1\|WP_002884629.1\|495530_495659_+\|DUF4044-domain-containing-protein	unknown	unknown	gnl\|CDD\|338651
NZ_CP018186.1\|WP_002886787.1\|477341_479294_+\|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-B	unknown	unknown	gnl\|CDD\|235542
NZ_CP018186.1\|WP_013990188.1\|492274_492640_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225093
NZ_CP018186.1\|WP_002884415.1\|497570_497768_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018186.1\|WP_045772206.1\|493345_493729_+\|PaaI-family-thioesterase	unknown	unknown	gnl\|CDD\|224961
NZ_CP018186.1\|WP_002886789.1\|481226_481874_+\|phosphoserine-phosphatase-SerB	unknown	unknown	gnl\|CDD\|319803

Protein	Function_ID	Function_description	E-value
NZ_CP018186.1\|WP_045772201.1\|488703_489048_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	3.39941e-50
NZ_CP018186.1\|WP_045772202.1\|489037_489697_+\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	7.22687e-111
NZ_CP018186.1\|WP_045772208.1\|494717_495449_+\|rRNA-pseudouridine-synthase	gnl\|CDD\|224108	COG1187, RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis].	2.11706e-95
NZ_CP018186.1\|WP_045772199.1\|483680_487838_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|273840	TIGR01865, conserved_hypothetical_protein, CRISPR subtype II/NMENI RNA-guided endonuclease Cas9/Csn1. CRISPR loci appear to be mobile elements with a wide host range. This model represents a protein found only in CRISPR-containing species, near other CRISPR-associated proteins (cas), as part of the NMENI subtype of CRISPR/Cas locus. The species range so far for this protein is animal pathogens and commensals only.	0
NZ_CP018186.1\|WP_045772207.1\|493742_494717_+\|hypothetical-protein	gnl\|CDD\|226231	COG3708, COG3708, Uncharacterized protein conserved in bacteria [Function unknown].	5.255e-08
NZ_CP018186.1\|WP_045772197.1\|482151_482913_+\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	4.44121e-27
NZ_CP018186.1\|WP_002886788.1\|479390_481115_+\|septation-ring-formation-regulator-EzrA	gnl\|CDD\|179877	PRK04778, PRK04778, septation ring formation regulator EzrA; Provisional.	0
NZ_CP018186.1\|WP_045772204.1\|491269_492160_-\|DMT-family-transporter	gnl\|CDD\|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	7.12399e-12
NZ_CP018186.1\|WP_002884694.1\|495753_497067_+\|GTPase-ObgE	gnl\|CDD\|237046	PRK12297, obgE, GTPase CgtA; Reviewed.	0
NZ_CP018186.1\|WP_045772194.1\|476780_477341_+\|HAD-IA-family-hydrolase	gnl\|CDD\|319825	cd07523, HAD_YsbA-like, uncharacterized family of the haloacid dehalogenase-like superfamily, similar to the uncharacterized Lactococcus lactis YsbA. The specific function of Lactococcus lactis YsbA is unknown. Members of this family belong to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	9.38212e-65
NZ_CP018186.1\|WP_045772205.1\|492886_493252_+\|OsmC-family-protein	gnl\|CDD\|376823	pfam02566, OsmC, OsmC-like protein. Osmotically inducible protein C (OsmC) is a stress -induced protein found in E. Coli. This family also contains a organic hydroperoxide detoxification protein that has a novel pattern of oxidative stress regulation.	3.93659e-07
NZ_CP018186.1\|WP_045772200.1\|487837_488707_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	1.51381e-126
NZ_CP018186.1\|WP_156209481.1\|482932_483319_+\|transposase	gnl\|CDD\|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	1.8739e-18
NZ_CP018186.1\|WP_002884629.1\|495530_495659_+\|DUF4044-domain-containing-protein	gnl\|CDD\|338651	pfam13253, DUF4044, Protein of unknown function (DUF4044). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 42 and 56 amino acids in length. There is a single completely conserved residue M that may be functionally important.	0.000482008
NZ_CP018186.1\|WP_002886787.1\|477341_479294_+\|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-B	gnl\|CDD\|235542	PRK05644, gyrB, DNA gyrase subunit B; Validated.	0
NZ_CP018186.1\|WP_013990188.1\|492274_492640_-\|hypothetical-protein	gnl\|CDD\|225093	COG2182, MalE, Maltose-binding periplasmic proteins/domains [Carbohydrate transport and metabolism].	0.000400519
NZ_CP018186.1\|WP_045772206.1\|493345_493729_+\|PaaI-family-thioesterase	gnl\|CDD\|224961	COG2050, PaaI, HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis, transport, and catabolism].	1.97504e-23
NZ_CP018186.1\|WP_002886789.1\|481226_481874_+\|phosphoserine-phosphatase-SerB	gnl\|CDD\|319803	cd07500, HAD_PSP, phosphoserine phosphatase (PSP), similar to Methanococcus Jannaschii PSP and Saccharomyces cerevisiae SER2p. This family includes Methanococcus jannaschii PSP, and Saccharomyces cerevisiae phosphoserine phosphatase SER2p, EC 3.1.3.3, which participates in a pathway whereby serine and glycine are synthesized from the glycolytic intermediate 3-phosphoglycerate; phosphoserine phosphatase catalyzes the hydrolysis of phospho-L-serine to L-serine and inorganic phosphate, the third reaction in this pathway. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	9.214e-101

>NZ_CP018186.1|WP_045772202.1|489037_489697_+|type-II-A-CRISPR-associated-protein-Csn2
MKINFSLLDEPMEISQGTVLVIEDVSVFAQIVKEFYQYDEQSNLTIFDSKIRSIKSSELLLITDILGYDINTSQVLKLLHTDIVSQLNDKPEVRSEIDSLVSLITDIIMAECLENELDIEYDEITLLELIKSLGIRIETTSCTVFEKIFEILQIFKYLVKKRILVFVNSLSYFSNDEIYQILEYTKLLQADVLFLEPRKIKGIQQFILDKDYILMPYNN
>NZ_CP018186.1|WP_045772201.1|488703_489048_+|CRISPR-associated-endonuclease-Cas2
MSYRYMRMILMFDMPTDTAEERKAYRKFRKFLLSEGFIMHQYSVYSKLLLNNTANTAMIGRLKANNPKKGNITILTVTEKQFARMIYLYGDKNTSVANSDERLVFLGEDYCDED
>NZ_CP018186.1|WP_045772200.1|487837_488707_+|type-II-CRISPR-associated-endonuclease-Cas1
MAGWRTIVVNTHSKLSYKNNHLIFRNSYKTEMIHLSEIDILLLETTDIVLTTMLVKRLVDENILVIFCDDKRLPTAFVTPYYARHDSSLQIARQISWKEDVKCEVWTAIIAQKILNQSYYLGECSFFEKSQSIMELYHGLEQFDPSNREGHSARIYFNTLFGNDFTRESDNDINAALDYGYTLLLSMFAREVVVCGCMTQIGLKHANQFNQFNLASDIMEPFRPIIDRIVYQNRHKNFVKIKKELFSIFSETYLYNGKEMYLSNIVSDYTKKVIKVLNQLGEGIPEFRI
>NZ_CP018186.1|WP_045772199.1|483680_487838_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MTKPYSIGLDIGTNSVGWAVITDDYKVPSKKMKVLGNTSKKYIKKNLLGALLFDSGITAEGRRLKRTARRRYTRRRNRILYLQEIFSTEMATLDDAFFQRLDDSFLVPDDKRDSKYPIFGNLVEEKAYHDEFPTIYHLRKYLADSTKKADLRLVYLALAHMIKYRGHFLIEGEFNSKNNDIQKNFQDFLDTYNAIFESDLSLENSKQLEEIVKDKISKSAKKDRILKLFPGEKNSGIFSEFLKLIVGNQADFKKYFNLDEKAPLHFSKESYDEDLETLLGYIGDDYSDVFLKAKKLYDAILLSGILTVTDNGTEAPLSSAMIMRYKEHEEDLALLKAYIRNISLETYNEVFKDDTKNGYAGYIDGKTSQEDFYVHLKKLLVGLEGADYFLEKIDREDFLRKQRTFDNGSIPYQIHLQEMRAILDKQAKFYPFLAKNKERIEKILTFRIPYYVGPLARGNSDFAWSIRKRNEKITPWNFEDVIDKESSAEAFINRMTSFDLYLPEEKVLPKHSLLYETFNVYNELTKVRFIAESMRDYQFLDSKQKKDIVRLYFKNKRRVTDKDIIEYLHAIDGYDGIELKGIEKQFNSSLSTYHDLLNIINDKEFLDDSSNEAIIEEIIHTLTIFEDREMIKQRLSKFENIFDKSVLKKLSRRHYTGWGKLSAKLINGIRDEKSGNTILDYLIDDGVSNRNFMQLIHDDALSFKKKIKKAQIIGDKDNIKQVVQALPGRPAIKKGILQSIKIVDELVKVMGRRPESIVVEMARENQYTNQGKSNSQQRLKRLEESLKELGSKILKENIPAKLSKIDNNALQNDRLYLYYLQNGKDMYTGEELDIDRLSNYDIDHIIPQAFLKDNSIDNKVLVSSASNRGKSDDVPSLEVVKKRKTLWYQLLKSKLISQRKFDNLTKAERGGLSPEAKAGFIQRQLVETRQITKHVARLLDERFNNKKDEDNKTLRTVKIITLKSSLVSQFRKDFELYKVREINDFHHAHDAYLNAVVASALLKKYPKLEPEFVYGDYPKYNSFRERKSATEKVYFYSNIMNIFKKSISLADGTVIERPLIEVNEETGESVWNKVADLNTVRKVLSYSQVNIVKKVEEQNHGLDRGKPKGLFNANLSSKPKPNSKENLVGAKEYLDPKKYGGYAGISNSFAVLVKGTIEKGAKKKITNILEFQGISILDRITYRKDKFNFLLEKGYKDIDLIIELPKYSLFELSDGSRRMLASILSTNNKRGEIHKGNQIFISQKYVKLLYHAKRISNTFNDNHRKYVENHKKEFEELFYYILEFNENYVGAKKNGELLKSAFQSWQNHSIDELCSSFIGPTGSERKGLFELTSRGGAADFDFLGVKIPRYRDYTPSSLLKDATLIHQSVTGLYETRIDLGKLGED
>NZ_CP018186.1|WP_156209481.1|482932_483319_+|transposase
MIPGMSETCAATILAEIGPDVKAFQSDAHLASWAGLCPGSYESAGIKKSSHITQGNRYIKQALTMSGLIAAHSKDNAFLSFYSKISQRGSKMKAVIACAHKLLRIIYKILATHQEYDKEKVLGLRQQF
>NZ_CP018186.1|WP_045772197.1|482151_482913_+|IS110-family-transposase
MEVMIETCCGIDVHQKSIVCCILDGPLESNKPKKIQKKFGTTTIALKNALDWLLENHVTHVFFESTGQYWVPLFNIFSDSELNLILANPQHIKNVPGRKTDMKDAEWIAQLGRCGFIEPSYIPSPEVMQLRLLTRRLRSYKQRQTQIKNEIHNLLQRANIKLTSYLSDIFSKTGQSLLTLFINGELIDYDNVTACIHKHVKASPEELMEAMNGKLSLEDRFLLEQSLEEYQLYQKLMNKLRSEIIAYIEKEFS
>NZ_CP018186.1|WP_002886789.1|481226_481874_+|phosphoserine-phosphatase-SerB
MSEVKGLLVMDVDSTLVQEEVIDLLGEEAGVGQEVAEITERAMRGELDFRQALNERVATLKGLPESIFDKVYARIHFNKGAKELVDELHARGFKVGLVSGGFHETVDRLAAEAGIDYVKANHLEVVDGVLTGKVYGEIVTKDVKVAKLKDWAAENGLELSQTIAMGDGANDLPMIKTAGIGIAFCAKPIVREQAPYQITERDLYKVIEILDEVRK
>NZ_CP018186.1|WP_002886788.1|479390_481115_+|septation-ring-formation-regulator-EzrA
MSSGIVLLIVVVVILVIIAYLIGILIRKRNDSRIAELEERKQSLFDLPVNEEIEEVKKLHLIGQSQTTFREWNQKWVDISTNSFTDIENHIFEAENMNDTFHFFKASGEINNIESQLDLVEEDIKSIREALSTLKEQEEKNSARVKHALDLYEELQNSIEENSDNFGSTMTEINKQLKNIEAEFAEFVTLNSSGDPIEASSILDRAEEHTIALGQISEKIPAIVAKLEDDFPDQLDDLESGYRKLIEQNYHFPEKNIERRFQEIREAIRSNSSELVSLDLDRAEEENVEIQDKINNLYSIFEREIASYKVVMRHKKILPDYLKHAKENNKKLQEELERLMLTYIFDETYAADVRSFASDISGVETAVLPTLENFEAQVKPFSELEKIFEKSLNTLSAVENGQVEVFENLQAIEKNEAKAREELDIYVNKLHVIKRYMEKRNLPGIPQSFLSVFFSTSAQIEALMDELSRGRINIDAVMRLTETSKNAIDHLEETAYLVVQNATLTEQLLQYSNRYRSFEPAVQSSFEHALKLFEVDHDYDASLEEISYALETVEPGVTDRFVSSYEKTREQIRM
>NZ_CP018186.1|WP_002886787.1|477341_479294_+|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-B
MTDELKNLEEKAQEYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLHHLVWEIVDNSIDEALAGFATHIQVFIEPDNSITVVDDGRGIPVDIQEKTGRPAVETVFTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKNGHIHFQEYKRGVVVADLAVIGETEKHGTTVHFTPDPEIFQETTEFDFGKLAKRIQELAFLNKGLRISITDKREGLEQEKHYHYEGGITSYVKYINENKDVIFDEPIYTDGEMDGISVEVAMQYTTGYHETVMSFANNIHTHEGGTHEQGFRTALTRVINDYARQNKILKEKDDNLTGDDVREGLTAIISVKHPNPQFEGQTKTKLGNSEVVKITNRLFSEALSRFLLENPAIAKKIVEKGILASKARIAAKRAREVTRKKSGLEISNLPGKLADCSSNNAEMNELFIVEGDSAGGSAKSGRNREFQAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYHKLVIMTDADVDGAHIRTLLLTLIYRFMRPVLESGYVYIAQPPIYGVKVGSEIKEYIQPGADQEDKLRAALEKYSVGRSKPTVQRYKGLGEMDDHQLWETTMDPENRLMARVSVDDAAEADKIFDMLMGDKVEPRREFIEENAVYSTLDI
>NZ_CP018186.1|WP_045772194.1|476780_477341_+|HAD-IA-family-hydrolase
MNYGDYIWDLGGTLLDNYQVSTQAFLATLEQFERTAEPQAVYDALKVSTSTAIDMFAPDIADFRTLYKQEEAKHLQEPVLFEGAKAVLAKIVAKGGRNFLVSHRNHLVLEILDKAEVASYFTEVVTSENGFARKPSPDSFLYLINKYDIKHGLVIGDRQIDIEAGKAAGLDTLLVDGHKSLLEIVT
>NZ_CP018186.1|WP_014634861.1|490992_491232_+|hypothetical-protein
MLYEYPAIFHTIEEGYQISFPDFGRSIRADSLPLAMTKASVFLSHIIKGYGDKPLPEPTAVSSIPNEEELVVLIQTELD
>NZ_CP018186.1|WP_045772204.1|491269_492160_-|DMT-family-transporter
MKNKIILGCLAAATCEILFGLSFIFTKSITAQVSDLALISWRFVTAFLFINLYFLFSRRRLKINGRNLKPLTRIAILNPIIYFICETIGIRMTTASESGAFLACIPVVALIMSSLILKEWPSRWQVVGVITTLIGIIIAVFAAGGSTHFSLVGYLILGLAVVSYALYCVDVERASQFSSLEITYFMLASGCLTFGLFALSQGFLAGDLKELLLLPVSNPKFTITILYQGLGCSVLGYLLSNFAIANIGVNRTASFIGISTIISILAAVVVLGEPFSQLQIFAGILVVLGVYVANKT
>NZ_CP018186.1|WP_013990188.1|492274_492640_-|hypothetical-protein
MKTFSKLTLASVSVLALLTLAACGNSKDKTDSSSSTTSSSKVTKESSSTDSSASVKVNKDGSTEVSDGNGNSAKTNGNNTVEANDSEGNSATVGQDGSVEVNSQDGTNVKVGSDGTVSIGN
>NZ_CP018186.1|WP_045772205.1|492886_493252_+|OsmC-family-protein
MYQTTIKGDKRFHSLSEGYGAPVELFGYTEDGETPMSLVNIALASCLTMCLQSYFAKYQGIEELAIQVDSNYEEGHFTLAIHLPEDLILENEQELLAFVDNFCRVKKLFREDIQVDISLAK
>NZ_CP018186.1|WP_045772206.1|493345_493729_+|PaaI-family-thioesterase
MQDKLHEIRVFENFQEELFETGHVIVTTEVVEKSLNYFGNAHGGYLFTLCDQVAGLVAISTGDYAVTLQSNINYLKAGHLSDQLKIEGLCVHNGKTTKVVEVVITNQEEKILTRATFTMYVTGSVEE
>NZ_CP018186.1|WP_045772207.1|493742_494717_+|hypothetical-protein
MSDFQTMDDFAVFVNDYLTPDQLSVQAYSYASDQQELSLLVTVDDYEMMCRWHAVWTFSGLHQAFFQSVMDLNNSFSIDSDSLAMKVRLRDQELLFQAMGLEMVVVDLPEPLFRLADVSFNEGGKHFTYLCEDQSVAAEDWVLVPIGSGNAEKEAFVEKISYVLADEVPVELTKLKKVIQKLDLVTVRYDVKVVRKGFLSFSGMAFEGEELGKPTDFLWVPFLAEQDDLAVPTYGIRINDGSRKTYVTVLAGEDDSMEMIALAPATYAVFKLRGPATAAVWESFHYAKKHFEMIDQPTVEVYPPGNRQAEDYEMEVWIPIKEEV
>NZ_CP018186.1|WP_045772208.1|494717_495449_+|rRNA-pseudouridine-synthase
MRLDKFLVDCGVGSRSQVKTFLKKKQVTVNGKVETSPKTQIDENQDQIAFQGQVLTHETFVYYLLNKPQGVISATEDARHKTVLDLLDDTARHKQVFPVGRLDIDTHGLLLLTNNGDLAHTMLSPKKHVDKIYQAKVDGIMNQEDILAFEKGIELKDHTCQPAKLEIISVDRATGTSLVQITIAEGKFHQVKRMVAACGKEVTELQRLSMGPLSLPSDLEVGAWRRLTEEELEALTVFGIPLA
>NZ_CP018186.1|WP_002884629.1|495530_495659_+|DUF4044-domain-containing-protein
MAFGDNGPRKKSFFERLTVLVVLIMLLVTVGALIFQAVAAVL
>NZ_CP018186.1|WP_002884694.1|495753_497067_+|GTPase-ObgE
MSMFLDTAKISVKAGRGGDGMVAFRREKYVPNGGPWGGDGGKGGSVIFKVDEGLRTLMDFRYNRKFKAKNGEKGMTKGMHGRGAEDLIVSIPPGTTVRDAETGKVITDMVEDGQEFVIAHGGRGGRGNIRFATPRNPAPEIAENGEPGEERELQLELKILADVGLVGFPSVGKSTILSVVTAAKPKIGAYHFTTIVPNLGMVRTKSGESFAMADLPGLIEGASQGVGLGTQFLRHIERTRVILHVIDMSASEGRDPYEDYLQINKELETYNLRLMERPQIIVANKMDMPGAEENLKEFKEKLAANYDEFDELPQIFPISSLAHQGLENLLEATAELLDETDEFLLYSEDDMEQEEVYYGFNEDERPFEISRDDDASWVLSGEKLEKLFVMTNMERDESIMKFARQLRGMGVDEALRERGAKDGDIVRIGNFEFEFVD
>NZ_CP018186.1|WP_002884415.1|497570_497768_+|hypothetical-protein
MGDKPISFRDKDGNFVSAADVWNPKKLEELFTRLNPNRKLRLERERLAREEAAKHPELNEETEQV

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Crispr_ID: NZ_CP018186_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018186_2

665605-665850

Orphan

Consensus_repeat	Method
CTCAACAAGTGCTTCAGAATCGGCAAGTACGTCAGCCTCAATGAGTGCTTCAAC	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP018186_2

>merge|NZ_CP018186|2|665605-665850|PILER-CR
CTCAACGAGTGCTTCAGAATCGGCAAGTACGTCAGCCTCAATGAGTGCTTCAACGAGTGCGTCTGAATCCGCAAGTACATCCGCGTCGATGAGTGCTTCAACCAGCGCCAGTGAATCGGCAAGTACGTCCGCGTCGATGAGTGCTTCAACAAGTGCATCAGAGTCAGCAAGTACCAGTGCCTCACAGAGTGCCTCGACAAGTGCTTCAGAATCGGCAAGTACGTCAGCCTCAATGAGTGCTTCAAC

>NZ_CP018186|2|2|665605-665850|PILER-CR
CTCAACGAGTGCTTCAGAATCGGCAAGTACGTCAGCCTCAATGAGTGCTTCAAC	GAGTGCGTCTGAATCCGCAAGTACATCCGCGTCGATGAGTGCTTCAACCAGCGCCAGT
GAATCGGCAAGTACGTCCGCGTCGATGAGTGCTTCAACAAGTGCATCAGAGTCA	GCAAGTACCAGTGCCTCACAGAGTGCCTCGACAAGTGCTTCA
GAATCGGCAAGTACGTCAGCCTCAATGAGTGCTTCAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018186.1\|WP_002886932.1\|695639_696707_+\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NZ_CP018186.1\|WP_156209993.1\|673556_681779_+\|accessory-Sec-dependent-serine-rich-glycoprotein-adhesin	unknown	unknown	gnl\|CDD\|375909
NZ_CP018186.1\|WP_013990278.1\|652837_655213_+\|accessory-Sec-system-translocase-SecA2	unknown	unknown	gnl\|CDD\|163426
NZ_CP018186.1\|WP_013990277.1\|652398_652845_+\|accessory-Sec-system-protein-Asp3	unknown	unknown	gnl\|CDD\|379726
NZ_CP018186.1\|WP_045772254.1\|650866_652396_+\|accessory-Sec-system-protein-Asp2	unknown	unknown	gnl\|CDD\|274739
NZ_CP018186.1\|WP_156209538.1\|688233_692217_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375450
NZ_CP018186.1\|WP_061652433.1\|696812_697376_+\|sugar-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100047
NZ_CP018186.1\|WP_061652428.1\|683102_687452_+\|glucosyltransferase	unknown	unknown	gnl\|CDD\|334895
NZ_CP018186.1\|WP_049553826.1\|649308_650874_+\|accessory-Sec-system-protein-Asp1	unknown	unknown	gnl\|CDD\|293598
NZ_CP018186.1\|WP_156209992.1\|655874_659876_+\|accessory-Sec-dependent-serine-rich-glycoprotein-adhesin	unknown	unknown	gnl\|CDD\|223039
NZ_CP018186.1\|WP_156209532.1\|647949_649170_+\|accessory-Sec-system-protein-translocase-subunit-SecY2	unknown	unknown	gnl\|CDD\|237095
NZ_CP018186.1\|WP_041817196.1\|655409_655634_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|374926
NZ_CP018186.1\|WP_079119909.1\|697498_697909_+\|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224759
NZ_CP018186.1\|WP_002886925.1\|693294_694104_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018186.1\|WP_156209536.1\|663372_663558_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018186.1\|WP_045772124.1\|694084_694756_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018186.1\|WP_156209534.1\|655226_655406_+\|Accessory-secretory-protein-Asp4	unknown	unknown	gnl\|CDD\|319060
NZ_CP018186.1\|WP_002886931.1\|694980_695655_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_CP018186.1\|WP_002886924.1\|692584_693301_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|213235
NZ_CP018186.1\|WP_156209531.1\|646708_647950_+\|glycosyl-hydrolase-family-8	unknown	unknown	gnl\|CDD\|133037

Protein	Function_ID	Function_description	E-value
NZ_CP018186.1\|WP_002886932.1\|695639_696707_+\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.16357e-26
NZ_CP018186.1\|WP_156209993.1\|673556_681779_+\|accessory-Sec-dependent-serine-rich-glycoprotein-adhesin	gnl\|CDD\|375909	pfam18483, Bact_lectin, Bacterial lectin. This entry primarily matches to legume-like lectin domains found in prokaryotes.	4.60464e-30
NZ_CP018186.1\|WP_013990278.1\|652837_655213_+\|accessory-Sec-system-translocase-SecA2	gnl\|CDD\|163426	TIGR03714, Protein_translocase_subunit_SecA_2, accessory Sec system translocase SecA2. Members of this protein family are homologous to SecA and part of the accessory Sec system. This system, including both five core proteins for export and a variable number of proteins for glycosylation, operates in certain Gram-positive pathogens for the maturation and delivery of serine-rich glycoproteins such as the cell surface glycoprotein GspB in Streptococcus gordonii. [Protein fate, Protein and peptide secretion and trafficking].	0
NZ_CP018186.1\|WP_013990277.1\|652398_652845_+\|accessory-Sec-system-protein-Asp3	gnl\|CDD\|379726	pfam15432, Sec-ASP3, Accessory Sec secretory system ASP3. Sec-ASP3 is family of bacterial proteins involved in the Sec secretory system. The family forms part of the accessory SecA2/SecY2 system specifically required to export GspB, a serine-rich repeat cell-wall glycoprotein adhesin encoded upstream in the same operon.	2.44804e-44
NZ_CP018186.1\|WP_045772254.1\|650866_652396_+\|accessory-Sec-system-protein-Asp2	gnl\|CDD\|274739	TIGR03712, acc_sec_asp2, accessory Sec system protein Asp2. This protein is designated Asp2 because, along with SecY2, SecA2, and other proteins it is part of the accessory secretory protein system. The system is involved in the export of serine-rich glycoproteins important for virulence in a number of Gram-positive species, including Streptococcus gordonii and Staphylococcus aureus. This protein family is assigned to transport rather than glycosylation function, but the specific molecular role is unknown. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	0
NZ_CP018186.1\|WP_156209538.1\|688233_692217_+\|hypothetical-protein	gnl\|CDD\|375450	pfam17965, MucBP_2, Mucin binding domain. This domain is found in bacterial cell surface proteins that interact with mucins. The archetypal member of this family is the Mub-R5 B1 domain. This domain has a beta-grasp fold.	1.05641e-18
NZ_CP018186.1\|WP_061652433.1\|696812_697376_+\|sugar-O-acetyltransferase	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	1.79126e-92
NZ_CP018186.1\|WP_049553826.1\|649308_650874_+\|accessory-Sec-system-protein-Asp1	gnl\|CDD\|293598	pfam16993, Asp1, Accessory Sec system protein Asp1. Asp1, along with SecY2, SecA2, and other proteins forms part of the accessory secretory protein system. The system is involved in the export of serine-rich glycoproteins important for virulence in a number of Gram-positive species, including Streptococcus gordonii and Staphylococcus aureus. This protein family is assigned to transport rather than glycosylation function, but the specific molecular role is unknown. Asp1 is predicted to be cytosolic.	2.34448e-168
NZ_CP018186.1\|WP_156209992.1\|655874_659876_+\|accessory-Sec-dependent-serine-rich-glycoprotein-adhesin	gnl\|CDD\|223039	PHA03307, PHA03307, transcriptional regulator ICP4; Provisional.	1.15214e-19
NZ_CP018186.1\|WP_156209532.1\|647949_649170_+\|accessory-Sec-system-protein-translocase-subunit-SecY2	gnl\|CDD\|237095	PRK12417, secY, preprotein translocase subunit SecY; Reviewed.	6.0895e-140
NZ_CP018186.1\|WP_041817196.1\|655409_655634_+\|hypothetical-protein	gnl\|CDD\|374926	pfam17000, Asp5, Accessory secretory protein Sec, Asp5. Asp4 and Asp5 are putative accessory components of the SecY2 channel of the SecA2-SecY2 mediated export system, but they are not present in all SecA2-SecY2 systems. This family of Asp5 is found in Firmicutes.	3.77373e-10
NZ_CP018186.1\|WP_079119909.1\|697498_697909_+\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224759	COG1846, MarR, Transcriptional regulators [Transcription].	2.1157e-12
NZ_CP018186.1\|WP_061652428.1\|683102_687452_+\|glucosyltransferase	gnl\|CDD\|334895	pfam02324, Glyco_hydro_70, Glycosyl hydrolase family 70. Members of this family belong to glycosyl hydrolase family 70 Glucosyltransferases or sucrose 6-glycosyl transferases (GTF-S) catalyze the transfer of D-glucopyramnosyl units from sucrose onto acceptor molecules, EC:2.4.1.5. This family roughly corresponds to the N-terminal catalytic domain of the enzyme. Members of this family also contain the Putative cell wall binding domain pfam01473, which corresponds with the C-terminal glucan-binding domain.	0
NZ_CP018186.1\|WP_156209534.1\|655226_655406_+\|Accessory-secretory-protein-Asp4	gnl\|CDD\|319060	pfam16996, Asp4, Accessory secretory protein Sec Asp4. Asp4 and Asp5 are putative accessory components of the SecY2 channel of the SecA2-SecY2 mediated export system, but they are not present in all SecA2-SecY2 systems. This family of Asp4 is found in Firmicutes.	2.39548e-11
NZ_CP018186.1\|WP_002886931.1\|694980_695655_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	4.11659e-60
NZ_CP018186.1\|WP_002886924.1\|692584_693301_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|213235	cd03268, ABC_BcrA_bacitracin_resist, ATP-binding cassette domain of the bacitracin-resistance transporter. The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.	5.75637e-86
NZ_CP018186.1\|WP_156209531.1\|646708_647950_+\|glycosyl-hydrolase-family-8	gnl\|CDD\|133037	cd04194, GT8_A4GalT_like, A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS.	3.63233e-73

>NZ_CP018186.1|WP_156209536.1|663372_663558_-|hypothetical-protein
MPPVSVGPVLDVLAWIFPYGKAVVTVTVAFPEASATVVPITLPAELLNVTVAPGEAVTAIC
>NZ_CP018186.1|WP_156209992.1|655874_659876_+|accessory-Sec-dependent-serine-rich-glycoprotein-adhesin
MFFRRNEGQYRETDRVTRFKLVKSGKHWLRAATSHFGLFKIISGRVDASSVSVHQVEEEVPLITSDRLLKGVAATGALLGGGVATYVVQADEATSPSAVEHTVSPTTDVLAASDSAVLGHSGAITESAVRGDVVSQSASATDSVSNSVDSVSLSLSASHQASASVSVSLSTSVSTSASMSASTSASESASTSASASQKASESTSVSMSGSKATGHASETSSSHVTATSQTGSESGAVSMRSEGLDTNETSRLSDLTTRASVPTVSAQAAEVASEATAVANTAVVASIEADKKRQEQEAKLTSLSTEIGTYLGRLAQLGDTESYILSVKPSLETMESALSASTSDLTSLVSQASIVKDTLSNFESQAIGSASESLSLHTSEILSLAYSESTSLSLEDLGSTEVANRLSMSKTTLEQNASEAQLLVSLADRYLNSVTDAQARADLSEAIQTVRTELTKANTLLSQNEGDFEGQRSRLGLAVEQMMSTMQQTGFTGNVVNSNGSQSIAINLAATANAVQTYLDSNGRRQYIYSGTLTGSDVSEGGKNTIIQSMTYSYDTGTNKTTWVVTVKPSFNTNNEFGILVTSDDTINSVTMTYHDNGNLITTEDWTSKLTKASSMPYSNLKAVRQQWRTIGGVADNMKWTIVTEGSNRNLYVRTATAIVESTLSGILTSDGNTAYQQRYDESPLAGLDIDDKNDAILSDSASQSASTSASMSASTSALQSASTSASASARTSASMSASISASQSALTSASESASTSASQSALTSASESASTSASQSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASQSASTSASESASTSASQSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASQSASTSASESASTSASQSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASQSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSTSTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSTSTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSVSESASTSASSSVITSMGEPAIHSLDSVDINSVIVSDSISMSVSASISLSVSASTSASISASQSASSSASESASTSASMSASTSASDSSPTSVASASSSESMSPKDHTEAKQLPKTGETESSLATLFGALATATGLAFLAKRKKDDPEDDSL
>NZ_CP018186.1|WP_041817196.1|655409_655634_+|hypothetical-protein
MQIFFMILLIILSVSLIITVTLQPRQIQIFSSDATSNIGRTSYWASQTLLKGLTLGLSSALFVVLLVMMVISYH
>NZ_CP018186.1|WP_156209534.1|655226_655406_+|Accessory-secretory-protein-Asp4
MTNKDLFHNSVEGRMEELKQKPIVKEKETRGEKINKIFFFMLGFVIIISLIFTLIGMLR
>NZ_CP018186.1|WP_013990278.1|652837_655213_+|accessory-Sec-system-translocase-SecA2
MFNSLNPLKPVKSVLKQVNGWAEQMAQLDDQSLKDKTTEFRERLDKGESLDDLLPEAYAVVREAAKRVLGMFPYDVQVMGAIVMHQGNIAEMSTGEGKTLTATMPVYLNALTGQGAILVTTNEYLAKRDAEEMGQVYEFLGLTIGVPFAEDGEELDTFEKREIYASDIIYTTNSGLGFDYLIDNLASNKDGKYMRPFNFAIIDEVDSVLLDSAQTPLVISGSPRVQSNYYAMINTLMTTLVEDQDYIFKEEKGEVWLTTKGAKLAENYLGISNLYAKENATFARHLIYALRAHTLFKKDKDYIVRQGKDGPEVVLLDKATGRLMELTKLQGGMHQAIEAKELVKLSPETRAMASVTYQSLFRKFKKISGMTGTGKTAEKEFLDTYGMQVVQIPTNRPKQRIDYPDNLYVTLPEKIYASLEYVKHYHRKGNPLLIFVGSVEMSELYSNLLLREGIAHNLLNANNAPREAEMIAESGQMGAVTVATSMAGRGTDIKLGPGVAELGGLVVIGTERMESQRIDLQIRGRSGRQGDPGMSKFFVSLEDDVIKKYGPNWVHKYYKDYTIDEKTESIELVGRRYRRLVEKAQRASDSAARFSRKQTLEYAESMNIQRELIYAQRNHLINQDQDLTDTIEQVLDDYIDIALVEEDLSEKEKLYHFILKNISFHIEKIPDDLDIDDVEAVAELIYQFAYREIDDKKKQLDTIDLFGYFQCLSLLKAIDDNWIEQVDYLQQLQQAIGSQTASQKNPIVEYYQEAFAGFETMKKQIKKDMVRNLLLSQVLVSEDGNIVTYFP
>NZ_CP018186.1|WP_013990277.1|652398_652845_+|accessory-Sec-system-protein-Asp3
MIHKNNSQIQWGTNVRSYMFGSQIEHHPDGSVNFSNPLIASGTEIHSWLAIQNYQASRKQPSLPLLKKGYIYRLESQFTTVPEGTVYLKLSFLNRYGEEVKQMIEKKQSFTFVYPHEAYNYSISLLSAGMVELDFKGMTITEVGEENV
>NZ_CP018186.1|WP_045772254.1|650866_652396_+|accessory-Sec-system-protein-Asp2
MSKISILQVGRDNWSNTYELPDNVRFFYLRAGLSSDILQCLKQAKLRNFNAVLVDSQESLLMLMDLRKSLVPYTIFYDADLLIEDHRVGRFLKEICAIPADFSDKQDLLDTLSKALFAGQYGDKLFPYQIQVHPRFEGKVIYNGFESISLDGNYGDSFKPILNWSFNIRVAEDFPVELWLEFEKAQTCQCRLVLRIIPEGSVSEIVRTIVVSEEEMRKGAIVLDQGRTYILSATLEAKGNGALRVGNFHQRWTRFQFGKFVLGGGILHDSKRQEINYFFYPGDFKPPLSVYFSGFRPAEGFEGFGMMRAMETPFLLFSDPRLEGGAFYMGTEELENSIKDTIQHYLDYLGFDSDQLILSGMSMGTFPSMYYGADFEPHAIIMSKPLANVGTIGNRARLLAPEVFPTGIDVLHLQTGRLDNEGVEALNQKFWDKFEKADFSNTTFGVSYMKDEDMDPTAFEDITKVLYSSGARILSKGTSGRHNDDHSTATAWFLNFYRMILENDFGRKG
>NZ_CP018186.1|WP_049553826.1|649308_650874_+|accessory-Sec-system-protein-Asp1
MYYLIPAWYGQGAEFWQPDLTPWYFRTSKIEFDDTLHQARIFQGQAMSPRLLLLAYQPHLRYFLHRFDLLEVSHFSVFDAIQGIKEQPMRCLQVSDLDWDDDCDFIFTPFVIVVEKHHQRFAEIELGPEGYLSLIRYYQDGLILREEIYDDRGFVSSILHFENGQATHRDYLNEDGIWQLCHFFDGRGIVSNPRTDHRFKKNYYISMEEVIWEFFDAYIAQELTPSDCFVVASKSNLNQTLYSHLPEANQKILTYFKERNQNDPLEDYASYLQLVDLIISDSQDFSTELRKLFPEQAEKIQHMASYDTRLALGKSQRLKSSKLYYQVNLDDISWEAIYQVLDFVANHQNTYIVFGTFNANPHDFDTFKEDVEHLISEKLNKKKFKHIKDNQSAENYLAENEEVEYRYDFVNLIDETALIKEFEYTRLIVDLSLEPHRYTQIAGISAGIPQINRVTSDYVTHLKNGYILEEVTQFEEAASYYLDQLKYWNQALIEAIEKIRENTGERFIEKWEHYLKEDKYV
>NZ_CP018186.1|WP_156209532.1|647949_649170_+|accessory-Sec-system-protein-translocase-subunit-SecY2
MKKISQSIVFKRLSWTVLFLFVYVLGSHLVLPFIDLKHPKLLGGLSNSIAFTSAMMGGNLSSFSLFSVGLSPWMSAMIIWQMFSFSKKSGLSKLPIEIQDRRKMYLTFAIALIQSLAVSLSLPIEVGIPKGLAILTNTILLIAGTFFLVWLSDLNSFFGIGGSIVILMASMVANLPRQIGESITRLHIGLPIILSLIIMGLLFLYIAVIVQRARYRIPINKVNIHNRFSQYSYLDVMLTPAGGMPFMYAISLVSIPQYLLILIQILFPKNGWTNTWIEALTVGHPIWLVLYQVVLFVLGIAFAFVNVSGEQIAERMRKSGEYIYNVYPGPDTSRYINKVVMKFAVIGAIYTVIMAGGPMMIVLINPQYLQLSMIPGMFLIYSGMVYNVREEIAAMTLNESYKGLFD
>NZ_CP018186.1|WP_156209531.1|646708_647950_+|glycosyl-hydrolase-family-8
MNNKNTVVLAGDYAYIRQIETALKSLCYHNRQLKIYLFNQDIPVEWFRATREHVERLGGELLDIKLIGPQFQMNWTNRLGHINHMTFARYFIPDFVHEDKVLYLDSDLIVTGNLDSLFEQELGDNYVGAVRSCFGAGVGFNAGVLLINNRLWKEEHIRQKLVDITEREHANVGEGDQSILNMVFEDRYLNLPDTYNFQIGFDAGAAEGGHRFVFEIPLEPLPLILHYISPDKPWNQFSVVRLREVWWRYCLMEWSQILKTWTNRGFELESNRESTVLTCYTLTNSYLLEQIEYLVQHLPQVHFIIAAYTYMATELLVLSRHPNVTLYQNTYPLLVEYELSKVDFYLDINHYDKLPEIYGYVTQNQLPLLTFENTQAPNQSYQAIFSHENPELMVNAINQLVAKRISERGESGC
>NZ_CP018186.1|WP_156209993.1|673556_681779_+|accessory-Sec-dependent-serine-rich-glycoprotein-adhesin
MFFRRNEGQYRETDRVTRFKLVKSGKHWLRAATSHFGLFKIISGRVDASSVSVHQVEEEVPLITSDRLLKGVAATGALLGGGVATYVVQADEATSPSAVEHTVSPTTDVLAASDSAVLGHSGAITESAVRGDVVSQSASATDSVSNSVDSVSLSASQQASASVSTSLSTSVSTSASTSASTSASESASTSASASQKASESTSVSMSGSKATGHDSETSSSQVTATSQTGSESGADSMRSEDLDTNETSRSSDLTTRASVPTVSVQAAEVTSEATAVANTALAVSIEADKKRQEQEAKLTSLSTEIGTYLGKLGNREGAESALLKGNATIEAIQNALTDPNADLNALISEATRTRNTVVNTVLRASSGARDYRNGARITAANTLRASYDTNASLGNATYDPKAHLIVTNKNQSTYFKTTGDASLSNGILTLTPSAPSQAGAYTLNTKIDMNESFTLTGKINLGEAYEGRNNNGHAGGDGIAAVFSTGAIGEIGNANGNGSGASLGMGGDNLKGSFGFKLDTWHNTGAPKPENKASADPKYSGYLKGAFGGFTYNYNGSNSTARGSVYPVIRTITKLNGEGPTDNSLKDYKVVYDGDTKVMTVTYNGQTWSMNLNNDPIAVNSDMPVDGHPNASALKYENKSRSLLQNAGYPDEMAFALFGSTGSGYNLQQFQLEKFDYSAQGAYITVKFIDADTGEEIPGKDEVLIQKTPGTNVDLGEYLAISGYTLKATNVSTAKGYLFGNTVKVVTGNQGITYAFHKIRQNEIYTASAKATTVYTLQGETASDLSDVSKFVTVASNESTTPAASGYSLVWSTPISTTTSGNQTAVAKVTYSDGSVQTVNVNYKVLPKIEAKTPIYDFKGQNLHNGSNADAYLSSDVTDQSYTTKWTNNSTSETTTTLPLSTATAGEFNYTITRTYDVGRYGTTSNSSELLVSTTTLKHKVIEVKGVSHTFEQDVDDEDYYNSYTPSEWYSTDSVSQSAILSANFVSSDLPDISTPGQHYYSVRFTTLPDGTGLSSTYELEVPYTVTPNRDSMSASTSASESAKTSASMSALASASESASTSASESMSTSESEKTSESVSASHSALTSASESASTSASQSASTSASESSSTSASMSASTSASESASTSASQSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASQSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASQSASTSASESASTSASQSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASQSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASQSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASQSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASQSASTSASESASTSASMSASTSASESASTSASQSASTSASESASTSASQSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASQSASTSASESASTSASQSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASQSASTSASESASTSASMSASTSASESASTSASQSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASQSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASQSASTSASESASTSASQSASTSASESASTSASQSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASQSASTSASESASTSASMSASTSASESASTSASQSASTSASESASTSASMSASTSASESASTSASQSASTSASESASTSASMSASTSASESASTSASQSASTSASESASTSASMSASTSASESASTSASQSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASQSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASQSASTSASESASTSASMSASTSASESASTSASMSASTSASESASTSASSSVITSMGEPAIHSLDSVDINSVIVSDSISVSVSASISLSVSASTSASISASQSASTSASISASQSVSISASDSSPTSVASASSSESMSPKDHTEAKQLPKTGETESSLATLFSALATATGLAFLAKRKKDEEEDEDY
>NZ_CP018186.1|WP_061652428.1|683102_687452_+|glucosyltransferase
MDKKVHYKMHKVKKQWVTIAVTGLSLGAVSAVSLGTNDGVVQADEHTDATVAIPDITVDTGTVSNDTTAAQDPTTAVAATNDVATDQATPTATFDLTTDTTNTVAANAVDTVATVGTDRAATTNDTTATNDTAVDTTNNNTTTDTTTVTDRAATTERRATGARRGPTGGRRATPVNGNTNNANNTVTVVNNDLPATNNVVTDGPSHIKTINGKQYYVEDDGTIRKNYVLERIGGSQYFNAETGELSNQKEYRFDKNGGTGSSADSTNTNVTVNGDKNAFYGTTDKDIELVDGYFTANTWYRPKEILKDGKEWTASTENDKRPLLTVWWPSKAIQASYLNYMKEQGLGTNQTYTSFSSQTQMDQAALEVQKRIEERIAREGNTDWLRTTIKNFVKTQPGWNSTSENLDNNDHLQGGALLYNNDSRTSHANSDYRLLNRTPTSQTGKHNPKYTKDTSNGGFEFLLANDIDNSNPAVQAEQLNWLHYIMNIGTITGGSEDENFDGVRVDAVDNVNADLLQIASDYFKAKYGADQSQDQAIKHLSILEAWSHNDAYYNEDTKGAQLPMDDPMHLALVYSLLRPIGNRSGVEPLISNSLNDRSESGKNSKRMANYAFVRAHDSEVQSIIGQIIKNEINPQSTGNTFTLDEMKKAFEIYNKDMRSANKQYTQYNIPSAYALMLTHKDTVPRVYYGDMYTDDGQYMAQKSPYYDAIETLLKGRIRYAAGGQDMKVNYIGYGNTNGWDAAGVLTSVRYGTGANSASDTGTAETRNQGMAVIVSNQPALRLTSNLTINMGAAHRNQAYRPLLLTTNDGVATYLNDSDANGIVKYTDGNGNLTFSANEIRGIRNPQVDGYLAVWVPVGASENQDVRVAPSKEKNSSGLVYESNAALDSQVIYEGFSNFQDFVQNPSQYTNKKIAENANLFKSWGITSFEFAPQYVSSDDGSFLDSVIQNGYAFTDRYDIGMSKDNKYGSLADLKAALKSLHAVGISAIADWVPDQIYNLPGDEVVTATRVNNYGETKDGAIIDHSLYAAKTRTFGNDYQGKYGGAFLDELKRLYPQIFDRVQISTGKRMTTDEKITKWSAKYMNGTNILDRGSEYVLKNGLNGYYGTNGGKVSLPKVVGSNQSTNGDNQNGDGSGKFEKRLFSVRYRYNNGQYAKNAFIKDNDGNVYYFDNSGRMAVGEKTIDGKQYFFLANGVQLRDGYRQNRRGQVFYYDQNGVLNANGKQDPKPDNNNNVSGRNQFVQIGNNVWAYYDGNGKRVTGHQNINGQELFFDNNGVQVKGRTVNENGAIRYYDANSGEMARNRFAEIEPGVWAYFNNDGTAVKGSQNINGQDLYFDQNGRQVKGALANVDGNLRYYDVNSGELYRNQFHEIDGSWYYFDGNGNAVKGMVTINGQNLLFDNNGKQIKGHLVRVNGIVRYYDPNSGEMAVNRWVEVSPGWWVYFDGEGRGQI
>NZ_CP018186.1|WP_156209538.1|688233_692217_+|hypothetical-protein
MRAYREDATEAAARTAEEHVAHGSGNTDLVDTIDLSKLLTRPKRHSDHRAPSPLDFARADEALFDNHAQSETVRIPSKQEIIFQGADSQTPDSEVMEKHVFTGTRDRKTGLIEWDKDSYTYPKIPVPVVQGYFADQKEAGFNVVTPYVPTVTEHVTYRKLGRIIPVTEDGEYIPGALTKQYNNNKKDPRKAGETAAPAVQDYMTDIKSVVPNKPGGDTPVVYRKIFKKASITYIDETTGAYLVSDQLTGELGEAIEYGTATRIKTFKDMGYDLIQDEFPKDAIFDDKDIDDQEWFVLLQHDVAKIGPDHEQVPDTPINPNNPDGPKWPSKYAYEKEVSFTVFYKSTDGNADLPDADVQKAYWVRTLTFDKVTGELVDETEWSPNKTKYYDIYAPVVLGYFADRVEVKGREVTEDNIEETITYVPLGKIIPIDANGRLIPNVPTPTFNNDANNPTKVSETLVPHIPGYRPMQQSVMPESLTDDILVEYTPILEDVTQPTLQTVFFKGAGEATPSVNIQSDFTFTGKYNQAEDTYTWDQDSHTYAKVNVPVIEGYYADKAVAGMQVVTPDKPEATDSVVYKELGKIIPVDTFGNPIADAEPVHYANDPQDATQVIETPAPQVAGYQAESELVLPIDLSLDQTLVYEPILDDITQDTKQTVTFQGAGYKDPVINIQDSFSFHGKFNQVEQTSTWDQESFTYDVVEVPVVEGFYADKRQAGGLEVRPDLPEVEDTVTYTELGKIIPVDEYGTPIENAPTPSYNNDPEDPTMAMETVVPDVLGYISEKAFITPEHPGQDTNVVYAKDEQKAIILYMNELDKSELTRDVVVGSSGEKIDYSTDEQIANLLKQGYELVNDGYAEAFDHTYNGDSDFDQVFEVVLRERLVLIDPDMPAPVAGEVVDPNDVNSPVWPNSVEMLENRADVTRTIQYVFEEGGLASDDYVEVLDFKRLANVNLVTGAINYEAWSSTQAGFSAVPSPEVVGFTPDRMEVAEMTEVSVETPEIMEVVTYLKDAQKATVTYVDGTTRKKLEVVDLLGKSGEVIEYSTIERIKYYSDRGYTLLADGFTNGVIFDGDSHVDQNFMVTLRHGTVQVGPDNIQEAGTPINPANPDGAKWPERESYIKDVTFTVLYTSSDGQAELPANNIQTAQWTRSLTIDKVTGEELGSSYWTSNKGQFETVITPEVEGYSADKDKVEGKTVGQRNLEETVVYIPLTGDINGKPKEDKADDILVEEIEDLEVLDQVEEQVEAHDGPVTYGPGDDFEAPVSSQAEGKGSKHKMPINLSNEEEASKGKIEETINIAGFTVSVTGLGLGRNGRKKKNKKDHKDQKDK
>NZ_CP018186.1|WP_002886924.1|692584_693301_+|ATP-binding-cassette-domain-containing-protein
MINITNLNKTYDDKVVLSNITFHANKGEITGLIGPNGSGKSTLIKILLGLESADSGKATILGTTYSELGAEPISIVGTFLDSYQPYPSRTGYEQLRWIALSCGLSKQRCIECLEIVGLKDVGKKKIKDYSLGMKQRLGLATAILADPDILILDEPINGLDPEGIRWLREFLKDFVKQEKTVLLTSHYMSELELTVDRVVGISNGHVVLNDKREQVLKQYDSFENAYFSSIHERSSVKC
>NZ_CP018186.1|WP_002886925.1|693294_694104_+|hypothetical-protein
MLSQVIKGYLYKYSHLTLFKMGLFILVVVSLFFTYQNIQVINALHTGAANSVNIDPNVIETPYRTVRDAILSSPYQATVLFLPILSALILATDYQFGEDEFSSLICANWKIRLFSQIFSIIAISITTTFTLFLLNALLLKFMLVSKLQSILSIGLMLDVFIRIVAFTITLNLLSLLLVKITKRSIPSLIVIVLLLVFSLSGILRAISPILDNLLPLIGAKSFAFSRIEAGQTTQVYGAILLLFETFLTTICLFYLEKIKWGKKNEKPIA
>NZ_CP018186.1|WP_045772124.1|694084_694756_+|hypothetical-protein
MKSQLHSLFYKKYSLLPVQVYLLFQLVFVIIISLLRYLKFEVNGDSITFSSSVLLTIISFSFLGNGVLNASVELKTQSYKQVYLNNGSRVKATLYILLIDLLECLTQSLLAGLIVMIFSQGTHSEVNFYYYLFGSVIYFLAGYSFSFLCGNSMIALAILLLFPILVLPFIDRVIPIASSVIIYDLVFQLIHTNYSIMRFIVFIIWLVGLFFTSYCLIRKEFLK
>NZ_CP018186.1|WP_002886931.1|694980_695655_+|response-regulator-transcription-factor
MVKSKILVIDDDLKILRLIKNILEKNSYVVETRNSVEDINLCDFIGFDLILLDIMMPVSGIDICSSIRSQIQTPIIFITAKNLEEDIVEAIGIGADDFITKPFGMKELVARVKMHIRRDKRLLSVGDTETSGLLQFDRVGKELIVDGNSISLSRREFNLLYLLFTYQTKIFSVEELYEYLYPQSSEVQYRSITEYIYQIRQKLKPYGIDPIKTLWGGGYKWQNQ
>NZ_CP018186.1|WP_002886932.1|695639_696707_+|HAMP-domain-containing-histidine-kinase
MAKSITLKQLIRATYLKIIFQFLICICFFYIIPALFTAVEGINANNVNSFTMFFSVSSWIYLCVILVVIIVRNVQKLLYEIQIEMKTVYEQSLYSDNNKYSKPLRLFEFIETKEHIMKMQDKIQKMLEKEKKQKQELMFRVSSAAHDLKTPLTIISGNAEYLQTFDLSPELTQCLLDIESSSQQLDNYFNQFIQYSKTFYKDNINKEHITSEQLASCLIRELTPLTTGTCVLKVLNETPSDTTIHIDLVLFLRALTNLVNNAMSYSQSMMPRIVIKLSSEQNKIVLSVWNDGSRFSANMIDNVGSLFYQDNQSGKDSQNHHFGIGLSFVKRVVELHDWELKLSNENNGAMVTIYI
>NZ_CP018186.1|WP_061652433.1|696812_697376_+|sugar-O-acetyltransferase
MPTEYEKMIAGDFYKPSDPKLRALAASSREKQWAFNAEPDRLKRAEIVKSWFGSTGENVAMNPQFVTDYGVNIHIGENFYSNWNLTMLDICPITIGDNAMIGPNCQFLTPLHPLDPTERNSGIEYGAPITIGDNFWAGGGVTILPGVTLGDNVVAGAGAVVTKSFGDNVVLGGNPARVIKEIPVKKD
>NZ_CP018186.1|WP_079119909.1|697498_697909_+|winged-helix-turn-helix-transcriptional-regulator
MDHFGRLLKQANNNMMRHFDQFARQYDLTGNQMAVIDFITNHADQEVFQRDIEHEFEIQRSTTTVLLQRMEKKGLIERHTSSKDARQKAVVLTNKAVKIASACQSYLRKEEEEFAQQFSAKEREVFLKILQHYRNI

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP018186_1	1.13\|490845\|30\|NZ_CP018186\|CRISPRCasFinder,CRT	490845-490874	30	NZ_CP020429	Streptococcus sp. FDAARGOS_192 plasmid unnamed1, complete sequence	60516-60545	0	1.0
NZ_CP018186_1	1.13\|490845\|30\|NZ_CP018186\|CRISPRCasFinder,CRT	490845-490874	30	NZ_CP018188	Streptococcus salivarius strain ICDC2 plasmid, complete sequence	78531-78560	0	1.0
NZ_CP018186_1	1.13\|490845\|30\|NZ_CP018186\|CRISPRCasFinder,CRT	490845-490874	30	MN480763	Streptococcus salivarius strain YU10 plasmid pSsal-YU10, complete sequence	81754-81783	0	1.0
NZ_CP018186_1	1.13\|490845\|30\|NZ_CP018186\|CRISPRCasFinder,CRT	490845-490874	30	MN480762	Streptococcus salivarius strain NU10 plasmid pSsal-NU10, complete sequence	44475-44504	0	1.0
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MH937501	Streptococcus phage CHPC1073, complete genome	8207-8236	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MH000602	Streptococcus phage D5842, complete genome	8205-8234	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MH937482	Streptococcus phage CHPC982, partial genome	9219-9248	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	KY705261	Streptococcus phage P5652, complete genome	8209-8238	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	KY705251	Streptococcus phage P0091, complete genome	8175-8204	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	KY705274	Streptococcus phage P7631, complete genome	9377-9406	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MH973662	Streptococcus phage SW7, complete genome	9041-9070	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	KY705256	Streptococcus phage P3681, complete genome	9819-9848	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MF161328	Streptococcus phage D4276, complete genome	8180-8209	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MF580761	Streptococcus phage 9A, complete genome	8410-8439	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MH937489	Streptococcus phage CHPC1034, partial genome	8589-8618	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MH892381	Streptococcus phage SWK5, complete genome	9101-9130	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MH937493	Streptococcus phage CHPC1041, complete genome	8290-8319	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MH892353	Streptococcus phage SW2, complete genome	10246-10275	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	KY705275	Streptococcus phage P7632, complete genome	9591-9620	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MF580760	Streptococcus phage 7T, complete genome	8157-8186	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MH892379	Streptococcus phage SWK3, complete genome	8868-8897	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MH892382	Streptococcus phage SWK6, complete genome	8977-9006	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	KY705266	Streptococcus phage P7152, complete genome	8784-8813	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MH937492	Streptococcus phage CHPC1040, complete genome	8264-8293	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MH937486	Streptococcus phage CHPC1027, complete genome	8191-8220	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MH937471	Streptococcus phage CHPC927, complete genome	8243-8272	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MH937500	Streptococcus phage CHPC1067, complete genome	8216-8245	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	KY705282	Streptococcus phage P8921, complete genome	8592-8621	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MH937477	Streptococcus phage CHPC950, complete genome	8605-8634	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	KY705267	Streptococcus phage P7154, complete genome	9532-9561	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MH937499	Streptococcus phage CHPC1062, complete genome	8287-8316	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MH937467	Streptococcus phage CHPC877, complete genome	8273-8302	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MH937466	Streptococcus phage CHPC875, complete genome	8880-8909	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MH937487	Streptococcus phage CHPC1029, complete genome	8276-8305	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MH937481	Streptococcus phage CHPC979, complete genome	8195-8224	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MH892356	Streptococcus phage SW21, complete genome	8894-8923	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	KY705264	Streptococcus phage P7134, complete genome	8214-8243	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MF580763	Streptococcus phage 16B8, complete genome	8174-8203	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	KY705276	Streptococcus phage P7633, complete genome	8275-8304	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MH892357	Streptococcus phage SW8, complete genome	8927-8956	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MH973661	Streptococcus phage SW5, complete genome	10104-10133	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MH892358	Streptococcus phage SW9, complete genome	8890-8919	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	KY705283	Streptococcus phage P8922, complete genome	9534-9563	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MH937485	Streptococcus phage CHPC1014, complete genome	8678-8707	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MH892378	Streptococcus phage SWK2, complete genome	9506-9535	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	KY705260	Streptococcus phage P5651, complete genome	8697-8726	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MH937472	Streptococcus phage CHPC928, complete genome	8616-8645	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MH892354	Streptococcus phage SW3, complete genome	8841-8870	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MH937488	Streptococcus phage CHPC1033, complete genome	9415-9444	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MH937508	Streptococcus phage CHPC1156, complete genome	8678-8707	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MH892352	Streptococcus phage SW1, complete genome	8792-8821	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	KY705257	Streptococcus phage P3684, complete genome	8678-8707	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MH892380	Streptococcus phage SWK4, complete genome	8868-8897	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	KY705265	Streptococcus phage P7151, complete genome	9820-9849	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MH892377	Streptococcus phage SWK1, complete genome	9037-9066	1	0.967
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	MG708273	Streptococcus phage vB_SthS_VA698, partial genome	20928-20957	1	0.967
NZ_CP018186_1	1.13\|490845\|30\|NZ_CP018186\|CRISPRCasFinder,CRT	490845-490874	30	NZ_CP020439	Streptococcus equinus strain FDAARGOS_251 plasmid unamed1 sequence	159106-159135	1	0.967
NZ_CP018186_1	1.13\|490845\|30\|NZ_CP018186\|CRISPRCasFinder,CRT	490845-490874	30	NZ_CP015284	Streptococcus salivarius strain ATCC 25975 plasmid, complete sequence	38258-38287	1	0.967
NZ_CP018186_1	1.13\|490845\|30\|NZ_CP018186\|CRISPRCasFinder,CRT	490845-490874	30	NZ_CP040803	Streptococcus salivarius strain LAB813 plasmid pSAL813, complete sequence	27948-27977	1	0.967
NZ_CP018186_1	1.1\|490054\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490054-490083	30	NC_018285	Streptococcus phage YMC-2011, complete genome	32157-32186	2	0.933
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	NC_018285	Streptococcus phage YMC-2011, complete genome	33474-33503	2	0.933
NZ_CP018186_1	1.10\|490647\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490647-490676	30	MK448979	Streptococcus phage Javan534, complete genome	2731-2760	2	0.933
NZ_CP018186_1	1.10\|490647\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490647-490676	30	MK448799	Streptococcus phage Javan535, complete genome	2731-2760	2	0.933
NZ_CP018186_1	1.10\|490647\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490647-490676	30	MF417874	Uncultured Caudovirales phage clone 3S_14, partial genome	13350-13379	2	0.933
NZ_CP018186_1	1.10\|490647\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490647-490676	30	MK448800	Streptococcus phage Javan539, complete genome	2731-2760	2	0.933
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	NC_000872	Streptococcus phage Sfi21, complete genome	8137-8166	2	0.933
NZ_CP018186_1	1.12\|490779\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490779-490808	30	AF115103	Streptococcus thermophilus bacteriophage Sfi21, complete genome	8137-8166	2	0.933
NZ_CP018186_1	1.1\|490054\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490054-490083	30	MH937468	Streptococcus phage CHPC879, complete genome	6574-6603	3	0.9
NZ_CP018186_1	1.1\|490054\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490054-490083	30	MH937493	Streptococcus phage CHPC1041, complete genome	6523-6552	3	0.9
NZ_CP018186_1	1.1\|490054\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490054-490083	30	MH937470	Streptococcus phage CHPC925, complete genome	6480-6509	3	0.9
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	MK448748	Streptococcus phage Javan389, complete genome	26483-26512	5	0.833
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	MK448751	Streptococcus phage Javan399, complete genome	24230-24259	5	0.833
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	MK448926	Streptococcus phage Javan392, complete genome	27194-27223	5	0.833
NZ_CP018186_1	1.3\|490185\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490185-490214	30	LR588166	Pseudomonas phage vB_PaeM_MIJ3	17804-17833	6	0.8
NZ_CP018186_1	1.3\|490185\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490185-490214	30	MH121069	Pseudomonas phage vB_PaeM_PA5oct, complete genome	134335-134364	6	0.8
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	MK448747	Streptococcus phage Javan385, complete genome	26364-26393	6	0.8
NZ_CP018186_1	1.10\|490647\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490647-490676	30	MK448706	Streptococcus phage Javan221, complete genome	2838-2867	6	0.8
NZ_CP018186_1	1.10\|490647\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490647-490676	30	MK448702	Streptococcus phage Javan199, complete genome	3220-3249	6	0.8
NZ_CP018186_1	1.3\|490185\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490185-490214	30	NZ_CP022246	Vibrio parahaemolyticus strain PB1937 plasmid p1937-2, complete sequence	76698-76727	7	0.767
NZ_CP018186_1	1.3\|490185\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490185-490214	30	NZ_CP013250	Vibrio parahaemolyticus strain FORC_022 plasmid, complete sequence	50008-50037	7	0.767
NZ_CP018186_1	1.3\|490185\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490185-490214	30	NZ_CP034300	Vibrio parahaemolyticus strain 20160303005-1 plasmid pVPSD2016-1, complete sequence	5023-5052	7	0.767
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	MH823906	Citrobacter phage Maroon, complete genome	20834-20863	7	0.767
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	JN882287	Cronobacter phage vB_CsaM_GAP161, complete genome	20049-20078	7	0.767
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	KT381880	Citrobacter phage Margaery, complete genome	21280-21309	7	0.767
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	NC_029094	Pseudoalteromonas phage H101, complete genome	11172-11201	7	0.767
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	MH892358	Streptococcus phage SW9, complete genome	8441-8470	7	0.767
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	MH892352	Streptococcus phage SW1, complete genome	8343-8372	7	0.767
NZ_CP018186_1	1.7\|490449\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490449-490478	30	NZ_CP018921	Serratia marcescens strain UMH7 plasmid unnamed4, complete sequence	10106-10135	7	0.767
NZ_CP018186_1	1.8\|490515\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490515-490544	30	NZ_CP016452	Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence	2128726-2128755	7	0.767
NZ_CP018186_1	1.11\|490713\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490713-490742	30	MN871445	UNVERIFIED: Serratia phage KpHz_2, complete genome	88653-88682	7	0.767
NZ_CP018186_1	1.1\|490054\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490054-490083	30	NC_007603	Enterobacteria phage RTP, complete genome	12592-12621	8	0.733
NZ_CP018186_1	1.1\|490054\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490054-490083	30	AM156909	Bacteriophage RTP, complete genome	12592-12621	8	0.733
NZ_CP018186_1	1.4\|490251\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490251-490280	30	MF417874	Uncultured Caudovirales phage clone 3S_14, partial genome	16460-16489	8	0.733
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	NZ_CP013044	Clostridium perfringens strain JP55 plasmid pJFP55J, complete sequence	22085-22114	8	0.733
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	MF580775	Streptococcus phage V2, complete genome	7944-7973	8	0.733
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	MH000602	Streptococcus phage D5842, complete genome	7757-7786	8	0.733
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	MH937459	Streptococcus phage CHPC595, complete genome	7766-7795	8	0.733
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	MF161328	Streptococcus phage D4276, complete genome	7729-7758	8	0.733
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	MH937474	Streptococcus phage CHPC930, complete genome	7770-7799	8	0.733
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	MF580762	Streptococcus phage 9B4, complete genome	8269-8298	8	0.733
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	MF580760	Streptococcus phage 7T, complete genome	7708-7737	8	0.733
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	MF580768	Streptococcus phage C0, complete genome	7723-7752	8	0.733
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	MH937483	Streptococcus phage CHPC1005, complete genome	9191-9220	8	0.733
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	KT717085	Streptococcus phage 128, complete genome	8069-8098	8	0.733
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	MH892359	Streptococcus phage SW10, complete genome	8652-8681	8	0.733
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	NC_002072	Streptococcus phage DT1, complete genome	8284-8313	8	0.733
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	MF580763	Streptococcus phage 16B8, complete genome	7725-7754	8	0.733
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	AF085222	Streptococcus thermophilus bacteriophage DT1, complete genome	8284-8313	8	0.733
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	MF580772	Streptococcus phage R1, complete genome	7944-7973	8	0.733
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	MF580764	Streptococcus phage 31B4, complete genome	7935-7964	8	0.733
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	MH892354	Streptococcus phage SW3, complete genome	8393-8422	8	0.733
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	MH937508	Streptococcus phage CHPC1156, complete genome	8230-8259	8	0.733
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	MF580765	Streptococcus phage A0, complete genome	7723-7752	8	0.733
NZ_CP018186_1	1.10\|490647\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490647-490676	30	NC_020879	Aeromonas phage Aes012, complete genome	43303-43332	8	0.733
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	MH937504	Streptococcus phage CHPC1091, complete genome	7817-7846	9	0.7
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	MF580769	Streptococcus phage L5A1, complete genome	7725-7754	9	0.7
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	MH937458	Streptococcus phage CHPC572, complete genome	7807-7836	9	0.7
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	MF580773	Streptococcus phage STP1, complete genome	7736-7765	9	0.7
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	MF580766	Streptococcus phage B0, complete genome	7736-7765	9	0.7
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	NC_013645	Streptococcus phage Abc2, complete genome	7737-7766	9	0.7
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	MF580774	Streptococcus phage STP2, complete genome	7724-7753	9	0.7
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	MH937469	Streptococcus phage CHPC919, complete genome	7779-7808	9	0.7
NZ_CP018186_1	1.5\|490317\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490317-490346	30	MF580767	Streptococcus phage B5, complete genome	7977-8006	9	0.7
NZ_CP018186_1	1.10\|490647\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490647-490676	30	NZ_CP043762	Paenibacillus sp. 37 plasmid pART37, complete sequence	80463-80492	9	0.7
NZ_CP018186_1	1.11\|490713\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490713-490742	30	NZ_CP050093	Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b5, complete sequence	208881-208910	9	0.7
NZ_CP018186_1	1.11\|490713\|30\|NZ_CP018186\|PILER-CR,CRISPRCasFinder,CRT	490713-490742	30	NC_008384	Rhizobium leguminosarum bv. viciae 3841 plasmid pRL11, complete sequence	336859-336888	9	0.7

1. spacer 1.13|490845|30|NZ_CP018186|CRISPRCasFinder,CRT matches to NZ_CP020429 (Streptococcus sp. FDAARGOS_192 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

tgaactaattaagacgattggagaacacaa	CRISPR spacer
tgaactaattaagacgattggagaacacaa	Protospacer
******************************

2. spacer 1.13|490845|30|NZ_CP018186|CRISPRCasFinder,CRT matches to NZ_CP018188 (Streptococcus salivarius strain ICDC2 plasmid, complete sequence) position: , mismatch: 0, identity: 1.0

tgaactaattaagacgattggagaacacaa	CRISPR spacer
tgaactaattaagacgattggagaacacaa	Protospacer
******************************

3. spacer 1.13|490845|30|NZ_CP018186|CRISPRCasFinder,CRT matches to MN480763 (Streptococcus salivarius strain YU10 plasmid pSsal-YU10, complete sequence) position: , mismatch: 0, identity: 1.0

tgaactaattaagacgattggagaacacaa	CRISPR spacer
tgaactaattaagacgattggagaacacaa	Protospacer
******************************

4. spacer 1.13|490845|30|NZ_CP018186|CRISPRCasFinder,CRT matches to MN480762 (Streptococcus salivarius strain NU10 plasmid pSsal-NU10, complete sequence) position: , mismatch: 0, identity: 1.0

tgaactaattaagacgattggagaacacaa	CRISPR spacer
tgaactaattaagacgattggagaacacaa	Protospacer
******************************

5. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH937501 (Streptococcus phage CHPC1073, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

6. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH000602 (Streptococcus phage D5842, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

7. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH937482 (Streptococcus phage CHPC982, partial genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

8. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to KY705261 (Streptococcus phage P5652, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

9. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to KY705251 (Streptococcus phage P0091, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

10. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to KY705274 (Streptococcus phage P7631, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

11. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH973662 (Streptococcus phage SW7, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

12. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to KY705256 (Streptococcus phage P3681, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

13. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MF161328 (Streptococcus phage D4276, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaagtcaaa	Protospacer
*************************** **

14. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MF580761 (Streptococcus phage 9A, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

15. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH937489 (Streptococcus phage CHPC1034, partial genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

16. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH892381 (Streptococcus phage SWK5, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

17. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH937493 (Streptococcus phage CHPC1041, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

18. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH892353 (Streptococcus phage SW2, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

19. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to KY705275 (Streptococcus phage P7632, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

20. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MF580760 (Streptococcus phage 7T, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

21. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH892379 (Streptococcus phage SWK3, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

22. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH892382 (Streptococcus phage SWK6, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

23. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to KY705266 (Streptococcus phage P7152, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

24. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH937492 (Streptococcus phage CHPC1040, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

25. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH937486 (Streptococcus phage CHPC1027, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

26. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH937471 (Streptococcus phage CHPC927, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

27. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH937500 (Streptococcus phage CHPC1067, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

28. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to KY705282 (Streptococcus phage P8921, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

29. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH937477 (Streptococcus phage CHPC950, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

30. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to KY705267 (Streptococcus phage P7154, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

31. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH937499 (Streptococcus phage CHPC1062, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

32. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH937467 (Streptococcus phage CHPC877, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

33. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH937466 (Streptococcus phage CHPC875, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

34. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH937487 (Streptococcus phage CHPC1029, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

35. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH937481 (Streptococcus phage CHPC979, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

36. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH892356 (Streptococcus phage SW21, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

37. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to KY705264 (Streptococcus phage P7134, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

38. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MF580763 (Streptococcus phage 16B8, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

39. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to KY705276 (Streptococcus phage P7633, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

40. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH892357 (Streptococcus phage SW8, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

41. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH973661 (Streptococcus phage SW5, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

42. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH892358 (Streptococcus phage SW9, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

43. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to KY705283 (Streptococcus phage P8922, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

44. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH937485 (Streptococcus phage CHPC1014, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

45. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH892378 (Streptococcus phage SWK2, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

46. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to KY705260 (Streptococcus phage P5651, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

47. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH937472 (Streptococcus phage CHPC928, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

48. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH892354 (Streptococcus phage SW3, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

49. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH937488 (Streptococcus phage CHPC1033, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

50. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH937508 (Streptococcus phage CHPC1156, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

51. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH892352 (Streptococcus phage SW1, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

52. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to KY705257 (Streptococcus phage P3684, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

53. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH892380 (Streptococcus phage SWK4, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

54. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to KY705265 (Streptococcus phage P7151, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

55. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH892377 (Streptococcus phage SWK1, complete genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

56. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MG708273 (Streptococcus phage vB_SthS_VA698, partial genome) position: , mismatch: 1, identity: 0.967

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagactaaaatctaa	Protospacer
************************.*****

57. spacer 1.13|490845|30|NZ_CP018186|CRISPRCasFinder,CRT matches to NZ_CP020439 (Streptococcus equinus strain FDAARGOS_251 plasmid unamed1 sequence) position: , mismatch: 1, identity: 0.967

tgaactaattaagacgattggagaacacaa	CRISPR spacer
cgaactaattaagacgattggagaacacaa	Protospacer
.*****************************

58. spacer 1.13|490845|30|NZ_CP018186|CRISPRCasFinder,CRT matches to NZ_CP015284 (Streptococcus salivarius strain ATCC 25975 plasmid, complete sequence) position: , mismatch: 1, identity: 0.967

tgaactaattaagacgattggagaacacaa	CRISPR spacer
agaactaattaagacgattggagaacacaa	Protospacer
 *****************************

59. spacer 1.13|490845|30|NZ_CP018186|CRISPRCasFinder,CRT matches to NZ_CP040803 (Streptococcus salivarius strain LAB813 plasmid pSAL813, complete sequence) position: , mismatch: 1, identity: 0.967

tgaactaattaagacgattggagaacacaa	CRISPR spacer
tgaactaattaagacgattggagaacacga	Protospacer
****************************.*

60. spacer 1.1|490054|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to NC_018285 (Streptococcus phage YMC-2011, complete genome) position: , mismatch: 2, identity: 0.933

accagcggtagtgatcttagcttgttccgc	CRISPR spacer
accagcggtagtgattttcgcttgttccgc	Protospacer
***************.** ***********

61. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to NC_018285 (Streptococcus phage YMC-2011, complete genome) position: , mismatch: 2, identity: 0.933

agtatttggtggatatgcacttacaggagc	CRISPR spacer
agtgtttggtggatatgcccttacaggagc	Protospacer
***.************** ***********

62. spacer 1.10|490647|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MK448979 (Streptococcus phage Javan534, complete genome) position: , mismatch: 2, identity: 0.933

cctctgtaagaggtttaccgtcgaacatca	CRISPR spacer
cctcggtaagtggtttaccgtcgaacatca	Protospacer
**** ***** *******************

63. spacer 1.10|490647|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MK448799 (Streptococcus phage Javan535, complete genome) position: , mismatch: 2, identity: 0.933

cctctgtaagaggtttaccgtcgaacatca	CRISPR spacer
cctcggtaagtggtttaccgtcgaacatca	Protospacer
**** ***** *******************

64. spacer 1.10|490647|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MF417874 (Uncultured Caudovirales phage clone 3S_14, partial genome) position: , mismatch: 2, identity: 0.933

cctctgtaagaggtttaccgtcgaacatca	CRISPR spacer
cctcggtaagtggtttaccgtcgaacatca	Protospacer
**** ***** *******************

65. spacer 1.10|490647|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MK448800 (Streptococcus phage Javan539, complete genome) position: , mismatch: 2, identity: 0.933

cctctgtaagaggtttaccgtcgaacatca	CRISPR spacer
cctcggtaagtggtttaccgtcgaacatca	Protospacer
**** ***** *******************

66. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to NC_000872 (Streptococcus phage Sfi21, complete genome) position: , mismatch: 2, identity: 0.933

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagaataaagtcaaa	Protospacer
******************* ******* **

67. spacer 1.12|490779|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to AF115103 (Streptococcus thermophilus bacteriophage Sfi21, complete genome) position: , mismatch: 2, identity: 0.933

gtgaagttgacccaaaagactaaagtctaa	CRISPR spacer
gtgaagttgacccaaaagaataaagtcaaa	Protospacer
******************* ******* **

68. spacer 1.1|490054|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH937468 (Streptococcus phage CHPC879, complete genome) position: , mismatch: 3, identity: 0.9

accagcggtagtgatcttagcttgttccgc	CRISPR spacer
tccagcggtggtaatcttagcttgttccgc	Protospacer
 ********.**.*****************

69. spacer 1.1|490054|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH937493 (Streptococcus phage CHPC1041, complete genome) position: , mismatch: 3, identity: 0.9

accagcggtagtgatcttagcttgttccgc	CRISPR spacer
tccagcggttgtaatcttagcttgttccgc	Protospacer
 ******** **.*****************

70. spacer 1.1|490054|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH937470 (Streptococcus phage CHPC925, complete genome) position: , mismatch: 3, identity: 0.9

accagcggtagtgatcttagcttgttccgc	CRISPR spacer
tccagcggtggtaatcttagcttgttccgc	Protospacer
 ********.**.*****************

71. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MK448748 (Streptococcus phage Javan389, complete genome) position: , mismatch: 5, identity: 0.833

-agtatttggtggatatgcacttacaggagc	CRISPR spacer
cggta-aaggtggttatgcacttacaggagc	Protospacer
 .***   ***** *****************

72. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MK448751 (Streptococcus phage Javan399, complete genome) position: , mismatch: 5, identity: 0.833

-agtatttggtggatatgcacttacaggagc	CRISPR spacer
cggta-aaggtggttatgcacttacaggagc	Protospacer
 .***   ***** *****************

73. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MK448926 (Streptococcus phage Javan392, complete genome) position: , mismatch: 5, identity: 0.833

-agtatttggtggatatgcacttacaggagc	CRISPR spacer
cggta-aaggtggttatgcacttacaggagc	Protospacer
 .***   ***** *****************

74. spacer 1.3|490185|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to LR588166 (Pseudomonas phage vB_PaeM_MIJ3) position: , mismatch: 6, identity: 0.8

atggtggcagtttacttctactggtactgc	CRISPR spacer
atggtggccatttacttctactggcaacac	Protospacer
******** .**************.* ..*

75. spacer 1.3|490185|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH121069 (Pseudomonas phage vB_PaeM_PA5oct, complete genome) position: , mismatch: 6, identity: 0.8

atggtggcagtttacttctactggtactgc	CRISPR spacer
atggtggccatttacttctactggcaacac	Protospacer
******** .**************.* ..*

76. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MK448747 (Streptococcus phage Javan385, complete genome) position: , mismatch: 6, identity: 0.8

-agtatttggtggatatgcacttacaggagc	CRISPR spacer
cggta-aaggcggttatgcacttacaggagc	Protospacer
 .***   **.** *****************

77. spacer 1.10|490647|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MK448706 (Streptococcus phage Javan221, complete genome) position: , mismatch: 6, identity: 0.8

cctctgtaagaggtttaccgtcgaacatca	CRISPR spacer
catcggtaagtggtttaccgtcgaaggtct	Protospacer
* ** ***** ************** .**

78. spacer 1.10|490647|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MK448702 (Streptococcus phage Javan199, complete genome) position: , mismatch: 6, identity: 0.8

cctctgtaagaggtttaccgtcgaacatca	CRISPR spacer
catcggtaagtggtttaccgtcgaaggtct	Protospacer
* ** ***** ************** .**

79. spacer 1.3|490185|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022246 (Vibrio parahaemolyticus strain PB1937 plasmid p1937-2, complete sequence) position: , mismatch: 7, identity: 0.767

atggtggcagtttacttctactggtactgc	CRISPR spacer
tttgatacactttacttctgctggtactgc	Protospacer
 * *  .** *********.**********

80. spacer 1.3|490185|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013250 (Vibrio parahaemolyticus strain FORC_022 plasmid, complete sequence) position: , mismatch: 7, identity: 0.767

atggtggcagtttacttctactggtactgc	CRISPR spacer
tttgatacactttacttctgctggtactgc	Protospacer
 * *  .** *********.**********

81. spacer 1.3|490185|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP034300 (Vibrio parahaemolyticus strain 20160303005-1 plasmid pVPSD2016-1, complete sequence) position: , mismatch: 7, identity: 0.767

atggtggcagtttacttctactggtactgc	CRISPR spacer
tttgatacactttacttctgctggtactgc	Protospacer
 * *  .** *********.**********

82. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH823906 (Citrobacter phage Maroon, complete genome) position: , mismatch: 7, identity: 0.767

agtatttggtggatatgcacttacaggagc	CRISPR spacer
ttgatttggtggataagcacgtacaggaat	Protospacer
   ************ **** *******..

83. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to JN882287 (Cronobacter phage vB_CsaM_GAP161, complete genome) position: , mismatch: 7, identity: 0.767

agtatttggtggatatgcacttacaggagc	CRISPR spacer
ttgatttggtggataagcacgtacaggaat	Protospacer
   ************ **** *******..

84. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to KT381880 (Citrobacter phage Margaery, complete genome) position: , mismatch: 7, identity: 0.767

agtatttggtggatatgcacttacaggagc	CRISPR spacer
ttgatttggtggataagcacgtacaggaat	Protospacer
   ************ **** *******..

85. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to NC_029094 (Pseudoalteromonas phage H101, complete genome) position: , mismatch: 7, identity: 0.767

agtatttggtggatatgcacttacaggagc	CRISPR spacer
cgcttttggtgaatatgcacttaaaggtgt	Protospacer
 *. *******.*********** *** *.

86. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH892358 (Streptococcus phage SW9, complete genome) position: , mismatch: 7, identity: 0.767

agtatttggtggatatgcacttacaggagc	CRISPR spacer
agtatttggtggatatacactcgctactgc	Protospacer
****************.****..* .  **

87. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH892352 (Streptococcus phage SW1, complete genome) position: , mismatch: 7, identity: 0.767

agtatttggtggatatgcacttacaggagc	CRISPR spacer
agtatttggtggatatacactcgctactgc	Protospacer
****************.****..* .  **

88. spacer 1.7|490449|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018921 (Serratia marcescens strain UMH7 plasmid unnamed4, complete sequence) position: , mismatch: 7, identity: 0.767

tgcaccaagcattgataaaccagaatggtc	CRISPR spacer
ggcatcaagcattgataaactagactcgat	Protospacer
 ***.***************.*** * * .

89. spacer 1.8|490515|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016452 (Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence) position: , mismatch: 7, identity: 0.767

taactgtcttgtggtagcggatattgtttt	CRISPR spacer
tgatcgtcttgtggtagccgatcttgttgc	Protospacer
*.*..************* *** ***** .

90. spacer 1.11|490713|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MN871445 (UNVERIFIED: Serratia phage KpHz_2, complete genome) position: , mismatch: 7, identity: 0.767

tattaaacgcttcaatcgtcgaggagctga	CRISPR spacer
tattaagtgcttcaatcgtcgaggttggta	Protospacer
******..****************     *

91. spacer 1.1|490054|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to NC_007603 (Enterobacteria phage RTP, complete genome) position: , mismatch: 8, identity: 0.733

accagcggtagtgatcttagcttgttccgc	CRISPR spacer
aaggtgagtagtgattttagcttgttctgc	Protospacer
*  .  .********.***********.**

92. spacer 1.1|490054|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to AM156909 (Bacteriophage RTP, complete genome) position: , mismatch: 8, identity: 0.733

accagcggtagtgatcttagcttgttccgc	CRISPR spacer
aaggtgagtagtgattttagcttgttctgc	Protospacer
*  .  .********.***********.**

93. spacer 1.4|490251|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MF417874 (Uncultured Caudovirales phage clone 3S_14, partial genome) position: , mismatch: 8, identity: 0.733

attatcctagcctttttgtgtatttgaaaa	CRISPR spacer
gttatcctagtctttttgtgtcttattgat	Protospacer
.*********.********** **   .*

94. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013044 (Clostridium perfringens strain JP55 plasmid pJFP55J, complete sequence) position: , mismatch: 8, identity: 0.733

agtatttggtggatatgcacttacaggagc	CRISPR spacer
ctcacaaagtggatatgcacttaaaggagc	Protospacer
  .*.  .*************** ******

95. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MF580775 (Streptococcus phage V2, complete genome) position: , mismatch: 8, identity: 0.733

agtatttggtggatatgcacttacaggagc	CRISPR spacer
agtatttggtggatatacactcgctacttc	Protospacer
****************.****..* .   *

96. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH000602 (Streptococcus phage D5842, complete genome) position: , mismatch: 8, identity: 0.733

agtatttggtggatatgcacttacaggagc	CRISPR spacer
agtatttggtggatatacactcgctacttc	Protospacer
****************.****..* .   *

97. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH937459 (Streptococcus phage CHPC595, complete genome) position: , mismatch: 8, identity: 0.733

agtatttggtggatatgcacttacaggagc	CRISPR spacer
agtatttggtggatatacactcgctacttc	Protospacer
****************.****..* .   *

98. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MF161328 (Streptococcus phage D4276, complete genome) position: , mismatch: 8, identity: 0.733

agtatttggtggatatgcacttacaggagc	CRISPR spacer
agtatttggtggatatacactcgctacttc	Protospacer
****************.****..* .   *

99. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH937474 (Streptococcus phage CHPC930, complete genome) position: , mismatch: 8, identity: 0.733

agtatttggtggatatgcacttacaggagc	CRISPR spacer
agtatttggtggatatacactcgctacttc	Protospacer
****************.****..* .   *

100. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MF580762 (Streptococcus phage 9B4, complete genome) position: , mismatch: 8, identity: 0.733

agtatttggtggatatgcacttacaggagc	CRISPR spacer
agtatttggtggatatacactcgctacttc	Protospacer
****************.****..* .   *

101. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MF580760 (Streptococcus phage 7T, complete genome) position: , mismatch: 8, identity: 0.733

agtatttggtggatatgcacttacaggagc	CRISPR spacer
agtatttggtggatatacactcgctacttc	Protospacer
****************.****..* .   *

102. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MF580768 (Streptococcus phage C0, complete genome) position: , mismatch: 8, identity: 0.733

agtatttggtggatatgcacttacaggagc	CRISPR spacer
agtatttggtggatatacactcgctacttc	Protospacer
****************.****..* .   *

103. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH937483 (Streptococcus phage CHPC1005, complete genome) position: , mismatch: 8, identity: 0.733

agtatttggtggatatgcacttacaggagc	CRISPR spacer
agtatttggtggatatacactcgctacttc	Protospacer
****************.****..* .   *

104. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to KT717085 (Streptococcus phage 128, complete genome) position: , mismatch: 8, identity: 0.733

agtatttggtggatatgcacttacaggagc	CRISPR spacer
agtatttggtggatatacactcgctacttc	Protospacer
****************.****..* .   *

105. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH892359 (Streptococcus phage SW10, complete genome) position: , mismatch: 8, identity: 0.733

agtatttggtggatatgcacttacaggagc	CRISPR spacer
agtatttggtggatatacactcgctacttc	Protospacer
****************.****..* .   *

106. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to NC_002072 (Streptococcus phage DT1, complete genome) position: , mismatch: 8, identity: 0.733

agtatttggtggatatgcacttacaggagc	CRISPR spacer
agtatttggtggatatacactcgctacttc	Protospacer
****************.****..* .   *

107. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MF580763 (Streptococcus phage 16B8, complete genome) position: , mismatch: 8, identity: 0.733

agtatttggtggatatgcacttacaggagc	CRISPR spacer
agtatttggtggatatacactcgctacttc	Protospacer
****************.****..* .   *

108. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to AF085222 (Streptococcus thermophilus bacteriophage DT1, complete genome) position: , mismatch: 8, identity: 0.733

agtatttggtggatatgcacttacaggagc	CRISPR spacer
agtatttggtggatatacactcgctacttc	Protospacer
****************.****..* .   *

109. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MF580772 (Streptococcus phage R1, complete genome) position: , mismatch: 8, identity: 0.733

agtatttggtggatatgcacttacaggagc	CRISPR spacer
agtatttggtggatatacactcgctacttc	Protospacer
****************.****..* .   *

110. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MF580764 (Streptococcus phage 31B4, complete genome) position: , mismatch: 8, identity: 0.733

agtatttggtggatatgcacttacaggagc	CRISPR spacer
agtatttggtggatatacactcgctacttc	Protospacer
****************.****..* .   *

111. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH892354 (Streptococcus phage SW3, complete genome) position: , mismatch: 8, identity: 0.733

agtatttggtggatatgcacttacaggagc	CRISPR spacer
agtatttggtggatatacactcgctacttc	Protospacer
****************.****..* .   *

112. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH937508 (Streptococcus phage CHPC1156, complete genome) position: , mismatch: 8, identity: 0.733

agtatttggtggatatgcacttacaggagc	CRISPR spacer
agtatttggtggatatacactcgctacttc	Protospacer
****************.****..* .   *

113. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MF580765 (Streptococcus phage A0, complete genome) position: , mismatch: 8, identity: 0.733

agtatttggtggatatgcacttacaggagc	CRISPR spacer
agtatttggtggatatacactcgctacttc	Protospacer
****************.****..* .   *

114. spacer 1.10|490647|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to NC_020879 (Aeromonas phage Aes012, complete genome) position: , mismatch: 8, identity: 0.733

cctctgtaagaggtttaccgtcgaacatca	CRISPR spacer
gttctttaagagttttaccgtcgaaaacgc	Protospacer
 .*** ****** ************ *.

115. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH937504 (Streptococcus phage CHPC1091, complete genome) position: , mismatch: 9, identity: 0.7

agtatttggtggatatgcacttacaggagc	CRISPR spacer
agtatttggtggatatacactcgttacttc	Protospacer
****************.****... .   *

116. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MF580769 (Streptococcus phage L5A1, complete genome) position: , mismatch: 9, identity: 0.7

agtatttggtggatatgcacttacaggagc	CRISPR spacer
agtatttggtggatatacactcgttacttc	Protospacer
****************.****... .   *

117. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH937458 (Streptococcus phage CHPC572, complete genome) position: , mismatch: 9, identity: 0.7

agtatttggtggatatgcacttacaggagc	CRISPR spacer
agtatttggtggatatacactcgttacttc	Protospacer
****************.****... .   *

118. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MF580773 (Streptococcus phage STP1, complete genome) position: , mismatch: 9, identity: 0.7

agtatttggtggatatgcacttacaggagc	CRISPR spacer
agtatttggtggatatacactcgttacttc	Protospacer
****************.****... .   *

119. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MF580766 (Streptococcus phage B0, complete genome) position: , mismatch: 9, identity: 0.7

agtatttggtggatatgcacttacaggagc	CRISPR spacer
agtatttggtggatatacactcgttacttc	Protospacer
****************.****... .   *

120. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to NC_013645 (Streptococcus phage Abc2, complete genome) position: , mismatch: 9, identity: 0.7

agtatttggtggatatgcacttacaggagc	CRISPR spacer
agtatttggtggatatacactcgttacttc	Protospacer
****************.****... .   *

121. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MF580774 (Streptococcus phage STP2, complete genome) position: , mismatch: 9, identity: 0.7

agtatttggtggatatgcacttacaggagc	CRISPR spacer
agtatttggtggatatacactcgttacttc	Protospacer
****************.****... .   *

122. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MH937469 (Streptococcus phage CHPC919, complete genome) position: , mismatch: 9, identity: 0.7

agtatttggtggatatgcacttacaggagc	CRISPR spacer
agtatttggtggatatacactcgttacttc	Protospacer
****************.****... .   *

123. spacer 1.5|490317|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to MF580767 (Streptococcus phage B5, complete genome) position: , mismatch: 9, identity: 0.7

agtatttggtggatatgcacttacaggagc	CRISPR spacer
agtatttggtggatatacactcgttacttc	Protospacer
****************.****... .   *

124. spacer 1.10|490647|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP043762 (Paenibacillus sp. 37 plasmid pART37, complete sequence) position: , mismatch: 9, identity: 0.7

cctctgtaagaggtttaccgtcgaacatca	CRISPR spacer
tctctctaagaggtttaccgtctcttccga	Protospacer
.**** ****************   . . *

125. spacer 1.11|490713|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP050093 (Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b5, complete sequence) position: , mismatch: 9, identity: 0.7

tattaaacgcttcaatcgtcgaggagctga	CRISPR spacer
ccgtaaacgcttcaatcggcgagcaggatc	Protospacer
.  *************** **** **

126. spacer 1.11|490713|30|NZ_CP018186|PILER-CR,CRISPRCasFinder,CRT matches to NC_008384 (Rhizobium leguminosarum bv. viciae 3841 plasmid pRL11, complete sequence) position: , mismatch: 9, identity: 0.7

tattaaacgcttcaatcgtcgaggagctga	CRISPR spacer
ccgtaaacgcttcaatcggcgagcaggatc	Protospacer
.  *************** **** **

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

334350 : 339826

Streptococcus_phage(66.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_045771733.1\|334350_335115_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	4.0e-15	25.2
WP_013990087.1\|335114_335825_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.1e-14	26.2
WP_070849374.1\|335959_336619_+	CBS domain-containing protein	M1NSC5	Streptococcus_phage	1.5e-66	58.7
WP_070849377.1\|336797_337724_-	cysteine synthase A	A0A1X9I5K7	Streptococcus_phage	1.2e-143	81.5
WP_070849380.1\|337825_338452_-	YigZ family protein	A0A1X9I5T8	Streptococcus_phage	4.6e-70	62.3
WP_084871141.1\|338506_339826_+	DEAD/DEAH box helicase	A0A1X9I5S6	Streptococcus_phage	6.4e-122	52.5

DBSCAN-SWA_2

412689 : 482913

Klosneuvirus(18.75%)

transposase,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_156209472.1\|412689_414681_+\|tRNA	methionine--tRNA ligase	A0A1V0SHR2	Klosneuvirus	9.8e-90	36.2
WP_045772172.1\|414888_415734_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	1.7e-46	37.8
WP_045772173.1\|415744_416641_-	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	1.4e-06	34.6
WP_156209473.1\|416880_417606_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_002886406.1\|417628_418615_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	5.4e-57	40.1
WP_002886728.1\|419116_421075_+	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_002886729.1\|421303_422143_+	CHAP domain-containing protein	NA	NA	NA	NA
WP_037603748.1\|423650_424676_+\|transposase	IS30-like element IS1139 family transposase	A0A2K9V2S9	Faecalibacterium_phage	7.2e-36	34.9
WP_014633524.1\|425948_426908_+	competence protein CoiA	NA	NA	NA	NA
WP_045772175.1\|426918_428724_+	oligoendopeptidase F	NA	NA	NA	NA
WP_014633522.1\|428936_430157_+	OFA family MFS transporter	NA	NA	NA	NA
WP_002886734.1\|430228_430936_+	O-methyltransferase	NA	NA	NA	NA
WP_045772176.1\|430997_432140_+\|protease	protease	NA	NA	NA	NA
WP_045772177.1\|432478_432964_+	UDP-N-acetylenolpyruvoylglucosamine reductase	NA	NA	NA	NA
WP_014633520.1\|432988_435607_+\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	6.0e-63	35.2
WP_002886752.1\|435798_436215_+\|transposase	IS200/IS605 family transposase	A0A1P8BMC0	Lactococcus_phage	1.8e-17	33.3
WP_045772178.1\|436532_436919_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_045772179.1\|437057_437750_+	hypothetical protein	NA	NA	NA	NA
WP_002885564.1\|437814_438105_+	hypothetical protein	NA	NA	NA	NA
WP_045772180.1\|438391_441508_+	YSIRK-type signal peptide-containing protein	F8HGP2	Streptococcus_phage	6.8e-05	32.5
WP_002886759.1\|441710_442463_+	response regulator transcription factor	A0A1V0E029	Clostridioides_phage	2.5e-22	32.7
WP_045772181.1\|442597_443263_+	hypothetical protein	NA	NA	NA	NA
WP_002886762.1\|443505_444240_+	response regulator transcription factor	A0A1V0E029	Clostridioides_phage	1.5e-24	33.3
WP_045772182.1\|444236_445556_+	GHKL domain-containing protein	NA	NA	NA	NA
WP_002886764.1\|445653_446220_+	transcriptional regulator	NA	NA	NA	NA
WP_045772183.1\|446510_450077_+	YSIRK-type signal peptide-containing protein	NA	NA	NA	NA
WP_002886767.1\|450209_450992_+	carbon-nitrogen family hydrolase	NA	NA	NA	NA
WP_013990171.1\|451001_452183_+	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_014633505.1\|452312_453335_+	N-acetyl-gamma-glutamyl-phosphate reductase	NA	NA	NA	NA
WP_045768481.1\|453364_454558_+	bifunctional ornithine acetyltransferase/N-acetylglutamate synthase	NA	NA	NA	NA
WP_002886771.1\|454584_455322_+	acetylglutamate kinase	NA	NA	NA	NA
WP_002886773.1\|455325_456456_+	acetylornithine transaminase	A0A1V0SKB7	Klosneuvirus	2.4e-24	27.5
WP_045772184.1\|456496_457375_-	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_002885943.1\|457548_458835_+	homoserine dehydrogenase	NA	NA	NA	NA
WP_156209475.1\|458918_459779_+	homoserine kinase	NA	NA	NA	NA
WP_156209477.1\|459771_460656_+	EamA family transporter RarD	NA	NA	NA	NA
WP_049528285.1\|460768_461386_+	hypothetical protein	NA	NA	NA	NA
WP_002886082.1\|461518_461722_+	hypothetical protein	NA	NA	NA	NA
WP_049528282.1\|462167_462746_+	flavin reductase family protein	NA	NA	NA	NA
WP_049528280.1\|462732_463302_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_013990181.1\|463294_464536_+	hypothetical protein	NA	NA	NA	NA
WP_156209479.1\|464564_467243_+\|tRNA	valine--tRNA ligase	A0A1V0S951	Catovirus	4.6e-151	40.9
WP_045772191.1\|467319_471792_+	hypothetical protein	NA	NA	NA	NA
WP_045772192.1\|471870_473091_+	DNA cytosine methyltransferase	V5URQ5	Oenococcus_phage	1.2e-130	58.2
WP_045772193.1\|473168_474749_+	hypothetical protein	V5US45	Oenococcus_phage	7.7e-21	29.6
WP_002884266.1\|475632_476007_+	murein hydrolase regulator LrgA	NA	NA	NA	NA
WP_002884772.1\|475999_476695_+	LrgB family protein	NA	NA	NA	NA
WP_045772194.1\|476780_477341_+	HAD-IA family hydrolase	NA	NA	NA	NA
WP_002886787.1\|477341_479294_+	DNA topoisomerase (ATP-hydrolyzing) subunit B	G3M9Z3	Bacillus_virus	1.5e-143	45.6
WP_002886788.1\|479390_481115_+	septation ring formation regulator EzrA	NA	NA	NA	NA
WP_002886789.1\|481226_481874_+	phosphoserine phosphatase SerB	NA	NA	NA	NA
WP_045772197.1\|482151_482913_+\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	3.6e-24	28.7

DBSCAN-SWA_3

970753 : 983497

Streptococcus_phage(37.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_156209687.1\|970753_972562_+	glutamine--fructose-6-phosphate transaminase (isomerizing)	A0A1J0F994	Only_Syngen_Nebraska_virus	6.2e-99	38.6
WP_156209689.1\|972679_973012_+	alkylphosphonate utilization protein	NA	NA	NA	NA
WP_002891087.1\|973212_973854_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_156209691.1\|973862_974492_+	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	1.0e-32	40.7
WP_021144064.1\|974504_975356_+	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_156209693.1\|975469_976885_+	DNA polymerase	M1Q231	Streptococcus_phage	2.7e-195	70.9
WP_070578503.1\|976881_977259_+	hypothetical protein	A0A1B0RXA8	Streptococcus_phage	1.2e-20	45.0
WP_002891080.1\|977236_977518_+	hypothetical protein	M1PG86	Streptococcus_phage	4.2e-23	58.4
WP_045772403.1\|977653_978673_+	alcohol dehydrogenase AdhP	A0A2K9L339	Tupanvirus	6.0e-27	25.5
WP_014633060.1\|979132_980026_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.1e-19	28.5
WP_013990505.1\|980022_980763_+	hypothetical protein	NA	NA	NA	NA
WP_070849709.1\|980755_981334_+	hypothetical protein	NA	NA	NA	NA
WP_002883901.1\|981934_983497_-	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	2.4e-19	30.3

DBSCAN-SWA_4

1393401 : 1401515

Streptococcus_phage(75.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000019067.1\|1393401_1394649_+\|transposase	ISL3 family transposase	Q6V7R1	Burkholderia_virus	3.9e-12	23.9
WP_000085862.1\|1394769_1394901_-	hypothetical protein	E4ZFP9	Streptococcus_phage	7.9e-17	100.0
WP_001038795.1\|1394905_1395643_-	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B)	E4ZFQ0	Streptococcus_phage	3.1e-134	99.2
WP_001814874.1\|1395767_1395851_-	23S rRNA methyltransferase attenuation leader peptide	NA	NA	NA	NA
WP_000398285.1\|1396056_1397277_-	XRE family transcriptional regulator	A0A1S5SEX3	Streptococcus_phage	1.3e-233	100.0
WP_000879507.1\|1397299_1397452_-	hypothetical protein	NA	NA	NA	NA
WP_000813488.1\|1397454_1398840_-	DNA translocase FtsK	A0A1S5SFB5	Streptococcus_phage	1.1e-265	100.0
WP_000985015.1\|1398868_1399255_-	YdcP family protein	A0A1S5SF96	Streptococcus_phage	3.0e-64	100.0
WP_000420682.1\|1399270_1399585_-	YdcP family protein	A0A1S5SF38	Streptococcus_phage	5.2e-54	100.0
WP_001825268.1\|1399607_1399727_-	hypothetical protein	NA	NA	NA	NA
WP_081528338.1\|1400037_1400667_-	ABC-2 transporter permease	NA	NA	NA	NA
WP_081528337.1\|1400666_1401515_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	6.4e-22	33.0

DBSCAN-SWA_5

1452643 : 1502179

Staphylococcus_phage(22.22%)

transposase,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004182765.1\|1452643_1453117_+\|tRNA	aminoacyl-tRNA deacylase	NA	NA	NA	NA
WP_004182766.1\|1453119_1453758_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_002890593.1\|1453921_1454824_-	HAD family hydrolase	NA	NA	NA	NA
WP_004182767.1\|1455143_1455623_-	hypothetical protein	NA	NA	NA	NA
WP_061652213.1\|1455636_1456890_-	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_073687074.1\|1457117_1458608_+\|tRNA	lysine--tRNA ligase	A0A2K9L3L6	Tupanvirus	2.3e-91	39.5
WP_004182770.1\|1459216_1460095_+	hypothetical protein	NA	NA	NA	NA
WP_156209809.1\|1460393_1461728_+	Mn(2+) uptake NRAMP transporter MntH	NA	NA	NA	NA
WP_002886106.1\|1461764_1461977_-	hypothetical protein	NA	NA	NA	NA
WP_037597639.1\|1462101_1462386_+	hypothetical protein	NA	NA	NA	NA
WP_002890576.1\|1462481_1463021_+	biotin transporter BioY	NA	NA	NA	NA
WP_002890574.1\|1463066_1463384_-	hypothetical protein	NA	NA	NA	NA
WP_021144422.1\|1463383_1464670_-	U32 family peptidase	Q6DW11	Phage_TP	3.5e-40	31.9
WP_037603903.1\|1464765_1465695_-	U32 family peptidase	NA	NA	NA	NA
WP_060971548.1\|1465933_1466230_+	DUF3270 domain-containing protein	NA	NA	NA	NA
WP_002886406.1\|1466343_1467330_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	5.4e-57	40.1
WP_002885903.1\|1467369_1467810_-	hypothetical protein	NA	NA	NA	NA
WP_002885965.1\|1467822_1468221_-	DUF948 domain-containing protein	NA	NA	NA	NA
WP_022495937.1\|1468345_1469137_-	prolipoprotein diacylglyceryl transferase	NA	NA	NA	NA
WP_002886095.1\|1469136_1470066_-	HPr kinase/phosphorylase	NA	NA	NA	NA
WP_002885986.1\|1470193_1470457_-	PspC domain-containing protein	NA	NA	NA	NA
WP_002886406.1\|1470517_1471504_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	5.4e-57	40.1
WP_045771834.1\|1471609_1472050_-	SprT family protein	NA	NA	NA	NA
WP_048674381.1\|1472036_1474169_-	RNA-binding transcriptional accessory protein	NA	NA	NA	NA
WP_004182784.1\|1474575_1475478_+	permease	NA	NA	NA	NA
WP_004182785.1\|1475477_1476293_+	TIGR03943 family protein	NA	NA	NA	NA
WP_014633339.1\|1476345_1478007_-	STAS domain-containing protein	NA	NA	NA	NA
WP_014633340.1\|1478256_1478871_-	hypothetical protein	NA	NA	NA	NA
WP_014633341.1\|1478966_1479608_-	lipase	NA	NA	NA	NA
WP_156209811.1\|1479634_1480246_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_021144436.1\|1480349_1480712_-	hypothetical protein	NA	NA	NA	NA
WP_021144437.1\|1480716_1481094_-	hypothetical protein	NA	NA	NA	NA
WP_037611464.1\|1481106_1481469_-	hypothetical protein	NA	NA	NA	NA
WP_021144439.1\|1481465_1481858_-	YbgA family protein	NA	NA	NA	NA
WP_045771841.1\|1482032_1482452_+	hypothetical protein	NA	NA	NA	NA
WP_045768928.1\|1482995_1483745_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_037603930.1\|1483836_1484148_-	hypothetical protein	NA	NA	NA	NA
WP_037603931.1\|1484255_1484837_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_045768929.1\|1484992_1485586_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_156209997.1\|1485682_1486366_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_045771843.1\|1486352_1487369_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_045771844.1\|1487389_1488145_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.2e-16	31.7
WP_045771845.1\|1488149_1489193_-	iron ABC transporter permease	NA	NA	NA	NA
WP_156209813.1\|1489363_1490116_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_156209815.1\|1490165_1491005_-	DUF4300 family protein	NA	NA	NA	NA
WP_156209817.1\|1491169_1492873_-	glycosyltransferase	NA	NA	NA	NA
WP_156209819.1\|1493347_1493983_-	copper homeostasis protein CutC	NA	NA	NA	NA
WP_004182865.1\|1494906_1495479_-	HD domain-containing protein	A0A285PXN3	Cedratvirus	1.5e-11	35.9
WP_004182867.1\|1495576_1496146_-	TetR/AcrR family transcriptional regulator	A0A1X9I6A2	Streptococcus_phage	1.6e-16	48.7
WP_156209821.1\|1496272_1497115_+	DegV family EDD domain-containing protein	A0A1X9I5J4	Streptococcus_phage	4.9e-107	69.2
WP_156209822.1\|1497344_1498517_+	MFS transporter	NA	NA	NA	NA
WP_156209824.1\|1498659_1499397_-	DUF4336 domain-containing protein	NA	NA	NA	NA
WP_156209826.1\|1499429_1500206_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_156209828.1\|1500501_1501389_+	helix-turn-helix domain-containing protein	U5TNA1	Satellite_phage	6.7e-06	33.0
WP_156209830.1\|1501393_1502179_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_6

1515735 : 1528194

Streptococcus_phage(87.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_156213427.1\|1515735_1516902_-	chorismate synthase	A0A291AU41	Pandoravirus	7.9e-39	34.7
WP_013990891.1\|1516902_1517970_-	3-dehydroquinate synthase	NA	NA	NA	NA
WP_156209834.1\|1517982_1518840_-	shikimate dehydrogenase	NA	NA	NA	NA
WP_156213428.1\|1518829_1519507_-	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	2.1e-113	92.9
WP_013990894.1\|1519503_1520667_-	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	1.5e-210	94.3
WP_013990895.1\|1520828_1523015_+	LTA synthase family protein	W6LM83	Streptococcus_phage	0.0e+00	95.0
WP_002886071.1\|1523185_1523371_+	hypothetical protein	W6LMT3	Streptococcus_phage	1.9e-24	93.4
WP_002886048.1\|1523524_1524829_-	phosphopyruvate hydratase	W6LP63	Streptococcus_phage	1.4e-246	99.5
WP_049528980.1\|1525034_1525490_+	YueI family protein	W6LLD2	Streptococcus_phage	5.0e-66	82.8
WP_049528977.1\|1527078_1528194_-	glycerate kinase	W6LM47	Streptococcus_phage	1.9e-135	85.2

DBSCAN-SWA_7

1689377 : 1695679

Streptococcus_phage(83.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004183081.1\|1689377_1689731_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	1.3e-40	67.5
WP_070850011.1\|1689765_1690260_-	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	9.1e-37	46.3
WP_004183085.1\|1690315_1691494_-	3-phosphoglycerate dehydrogenase	M1NSB9	Streptococcus_phage	3.0e-179	79.8
WP_002884484.1\|1691512_1692070_-	GNAT family N-acetyltransferase	M1PSC3	Streptococcus_phage	2.0e-56	59.6
WP_070850013.1\|1692082_1693177_-	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	1.3e-171	81.0
WP_156209906.1\|1693331_1694225_-	ROK family protein	NA	NA	NA	NA
WP_004183092.1\|1694340_1694736_+	lactoylglutathione lyase	NA	NA	NA	NA
WP_004183097.1\|1694779_1695679_-	SPFH domain-containing protein	A0A1V0SL90	Klosneuvirus	1.8e-35	32.8

DBSCAN-SWA_8

1814743 : 1864082

Staphylococcus_phage(40.0%)

bacteriocin,transposase,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003018306.1\|1814743_1816186_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB	NA	NA	NA	NA
WP_014632690.1\|1816185_1817652_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA	NA	NA	NA
WP_002884769.1\|1817651_1817954_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	NA	NA	NA	NA
WP_080936860.1\|1818093_1818531_-	glycosyltransferase	NA	NA	NA	NA
WP_045772000.1\|1818554_1819994_-	6-phospho-beta-glucosidase	NA	NA	NA	NA
WP_045772001.1\|1820146_1820656_-	peptide-methionine (S)-S-oxide reductase MsrA	NA	NA	NA	NA
WP_045772002.1\|1820667_1821516_-	MetQ/NlpA family ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_045772003.1\|1821637_1822189_-	cysteine hydrolase	G3MA16	Bacillus_virus	2.6e-24	40.3
WP_045772004.1\|1822255_1823041_-	GTP-sensing pleiotropic transcriptional regulator CodY	NA	NA	NA	NA
WP_002884715.1\|1823308_1824523_-	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_002891687.1\|1824886_1825339_+	universal stress protein	NA	NA	NA	NA
WP_004183318.1\|1825417_1826170_-	hypothetical protein	NA	NA	NA	NA
WP_156209931.1\|1826239_1827040_-	pyruvate formate lyase-activating protein	A0A2P0VNQ0	Tetraselmis_virus	1.7e-24	31.8
WP_149561188.1\|1827226_1827964_-	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_045769057.1\|1828317_1829649_-	HlyC/CorC family transporter	NA	NA	NA	NA
WP_045769056.1\|1829759_1830542_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	4.7e-11	24.9
WP_004183325.1\|1830725_1832792_-	sodium:proton antiporter	NA	NA	NA	NA
WP_014634967.1\|1832800_1833043_-	hypothetical protein	NA	NA	NA	NA
WP_045772008.1\|1833039_1833588_-	SAM-dependent methyltransferase	A0A2H4PQV0	Staphylococcus_phage	7.0e-38	44.1
WP_004183328.1\|1833584_1834529_-	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	1.2e-34	46.2
WP_045769055.1\|1834614_1835691_-	PDZ domain-containing protein	NA	NA	NA	NA
WP_045772009.1\|1835668_1836166_-	pantetheine-phosphate adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	2.9e-14	29.4
WP_080936862.1\|1836198_1836762_-	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	NA	NA	NA	NA
WP_002884706.1\|1836887_1837808_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	1.2e-87	52.6
WP_002884393.1\|1837873_1838098_-	DUF4059 family protein	NA	NA	NA	NA
WP_156209932.1\|1838309_1839053_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	4.7e-29	39.6
WP_118058287.1\|1839052_1839799_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_045772011.1\|1840395_1841226_-	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_045772012.1\|1841440_1842331_-	hypothetical protein	NA	NA	NA	NA
WP_045769047.1\|1842431_1843541_-	DNA polymerase IV	NA	NA	NA	NA
WP_045769046.1\|1843808_1846121_+	formate C-acetyltransferase	A0A2P0VNR5	Tetraselmis_virus	1.1e-113	32.4
WP_070847041.1\|1846431_1848126_+	oleate hydratase	NA	NA	NA	NA
WP_045769044.1\|1848412_1849195_+	carbonic anhydrase family protein	NA	NA	NA	NA
WP_004183346.1\|1849280_1849733_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_156209933.1\|1850395_1851343_-	serine hydrolase	A0A1D8EXR7	Mycobacterium_phage	2.5e-06	25.7
WP_156209934.1\|1851342_1852098_-	peptidase	NA	NA	NA	NA
WP_013991113.1\|1852269_1852941_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_013990693.1\|1852995_1853982_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	3.2e-57	40.4
WP_014632658.1\|1854115_1854982_-	aquaporin family protein	M1HJ77	Paramecium_bursaria_Chlorella_virus	2.6e-18	28.4
WP_156209935.1\|1855103_1857371_+	Xaa-Pro dipeptidyl-peptidase	NA	NA	NA	NA
WP_013990693.1\|1857390_1858377_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	3.2e-57	40.4
WP_014634984.1\|1858539_1858920_-	hypothetical protein	NA	NA	NA	NA
WP_156209936.1\|1859044_1859461_-	hypothetical protein	NA	NA	NA	NA
WP_070579661.1\|1859627_1859924_-\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
WP_002886406.1\|1860240_1861227_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	5.4e-57	40.1
WP_156213432.1\|1861532_1861739_-	hypothetical protein	NA	NA	NA	NA
WP_156209938.1\|1862334_1862490_-	hypothetical protein	NA	NA	NA	NA
WP_156209939.1\|1862789_1864082_-\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	4.3e-187	82.0

DBSCAN-SWA_9

1995656 : 2049667

Streptococcus_phage(37.5%)

protease,bacteriocin,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_156209961.1\|1995656_1997183_-\|transposase	IS1182 family transposase	A0A1X9I5T2	Streptococcus_phage	3.6e-209	76.8
WP_045771681.1\|1997311_1997725_-	acyl-CoA thioesterase	NA	NA	NA	NA
WP_014632569.1\|1997742_1998078_-	thiol reductase thioredoxin	NA	NA	NA	NA
WP_013991220.1\|2003599_2004742_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	7.1e-85	42.8
WP_002885866.1\|2004948_2005083_-	50S ribosomal protein L34	NA	NA	NA	NA
WP_013991221.1\|2005278_2005842_-	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_156209962.1\|2005838_2006435_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_156209963.1\|2006566_2007610_-	KH domain-containing protein	NA	NA	NA	NA
WP_037605452.1\|2007621_2008428_-	membrane protein insertase YidC	NA	NA	NA	NA
WP_002891957.1\|2008543_2008879_-	ribonuclease P protein component	NA	NA	NA	NA
WP_037601513.1\|2008963_2010349_-	argininosuccinate lyase	NA	NA	NA	NA
WP_156209964.1\|2010675_2011875_-	argininosuccinate synthase	NA	NA	NA	NA
WP_002886967.1\|2013908_2014652_-	response regulator transcription factor	NA	NA	NA	NA
WP_049529280.1\|2014653_2015970_-	GHKL domain-containing protein	NA	NA	NA	NA
WP_049529279.1\|2015993_2017274_-	hypothetical protein	NA	NA	NA	NA
WP_149561142.1\|2017295_2018186_-	histidine kinase	NA	NA	NA	NA
WP_002885760.1\|2018245_2019553_-	GHKL domain-containing protein	NA	NA	NA	NA
WP_037611119.1\|2020002_2021457_-\|tRNA	glutamate--tRNA ligase	NA	NA	NA	NA
WP_156209965.1\|2021692_2023663_-	peptide ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_002885800.1\|2023844_2024534_-	50S ribosomal protein L1	NA	NA	NA	NA
WP_002885648.1\|2024633_2025059_-	50S ribosomal protein L11	NA	NA	NA	NA
WP_002885872.1\|2025230_2025584_+	DUF3397 domain-containing protein	NA	NA	NA	NA
WP_156209966.1\|2025678_2026176_-	carbonic anhydrase	NA	NA	NA	NA
WP_037598509.1\|2026327_2027023_-	TIGR00266 family protein	NA	NA	NA	NA
WP_073686093.1\|2027111_2028473_-	DNA repair protein RadA	NA	NA	NA	NA
WP_061652425.1\|2028469_2028937_-	cysteine hydrolase	NA	NA	NA	NA
WP_156209967.1\|2028947_2029394_-	dUTP diphosphatase	Q332E8	Clostridium_botulinum_C_phage	1.4e-33	50.7
WP_002886986.1\|2029601_2030204_+	NAD(P)H-dependent oxidoreductase	A0A2P0ZL77	Lactobacillus_phage	1.8e-55	54.2
WP_002885631.1\|2030222_2031473_+	NAD(P)H-dependent oxidoreductase	A0A2P0ZL82	Lactobacillus_phage	7.6e-56	52.7
WP_013991240.1\|2032389_2032950_+	MptD family putative ECF transporter S component	NA	NA	NA	NA
WP_045769394.1\|2033068_2034091_+	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_002886993.1\|2034107_2035022_+	UTP--glucose-1-phosphate uridylyltransferase GalU	A0A127AW70	Bacillus_phage	2.8e-76	51.9
WP_013991242.1\|2035067_2035742_-\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
WP_045769393.1\|2035732_2036260_-	5-formyltetrahydrofolate cyclo-ligase	NA	NA	NA	NA
WP_045769392.1\|2036328_2037462_-	N-acetyldiaminopimelate deacetylase	NA	NA	NA	NA
WP_002886999.1\|2037539_2038238_-	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase	NA	NA	NA	NA
WP_002887000.1\|2038323_2039076_-	HAD family hydrolase	NA	NA	NA	NA
WP_002887001.1\|2039189_2040029_-	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_002885650.1\|2040449_2040608_+\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
WP_002887002.1\|2040627_2040795_+\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
WP_045001373.1\|2040842_2041097_+	hypothetical protein	NA	NA	NA	NA
WP_049529273.1\|2041182_2041701_-	nucleoside deaminase	NA	NA	NA	NA
WP_049529272.1\|2042470_2042863_-	single-stranded DNA-binding protein	A1EAD1	Streptococcus_phage	1.3e-25	46.2
WP_003095911.1\|2043092_2043320_-	sulfurtransferase TusA family protein	NA	NA	NA	NA
WP_049529271.1\|2043334_2044366_-	YeeE/YedE family protein	NA	NA	NA	NA
WP_049529270.1\|2044503_2045127_-\|tRNA	DUF4479 and tRNA-binding domain-containing protein	NA	NA	NA	NA
WP_045771798.1\|2045136_2045451_-	thioredoxin family protein	NA	NA	NA	NA
WP_045771799.1\|2045447_2045732_-	DUF4651 domain-containing protein	NA	NA	NA	NA
WP_045771800.1\|2045831_2046899_+	glutamyl aminopeptidase	NA	NA	NA	NA
WP_045771801.1\|2046914_2047685_+	pyrroline-5-carboxylate reductase	A0A1X9I6T5	Streptococcus_phage	5.6e-33	35.7
WP_045771802.1\|2047711_2048374_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_045001368.1\|2048486_2048933_-	hypothetical protein	NA	NA	NA	NA
WP_014632546.1\|2049010_2049667_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_10

2151724 : 2159718

Streptococcus_phage(83.33%)

integrase

attL 2150611:2150670|attR 2159769:2159832

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2150611:2150670	attL	NA	NA	NA	NA
WP_156209999.1\|2151724_2152147_-	autolysin	A0A286QMV0	Streptococcus_phage	1.2e-37	61.0
WP_156209974.1\|2152186_2152957_-	hypothetical protein	NA	NA	NA	NA
WP_156209975.1\|2153264_2154773_-	DNA primase	Q9AZI5	Lactococcus_phage	2.1e-60	32.3
WP_156209976.1\|2154762_2155623_-	hypothetical protein	A0A1X9I6L2	Streptococcus_phage	1.0e-107	65.7
WP_023909303.1\|2155638_2155911_-	MerR family transcriptional regulator	A0A1X9I5U9	Streptococcus_phage	1.4e-18	50.6
WP_156210000.1\|2155912_2156224_-	hypothetical protein	NA	NA	NA	NA
WP_156209977.1\|2156240_2156474_-	hypothetical protein	NA	NA	NA	NA
WP_156209978.1\|2156507_2156786_-	hypothetical protein	NA	NA	NA	NA
WP_156209979.1\|2156797_2157004_-	hypothetical protein	NA	NA	NA	NA
WP_156209980.1\|2157008_2157308_-	hypothetical protein	NA	NA	NA	NA
WP_156209981.1\|2157547_2157733_-	hypothetical protein	NA	NA	NA	NA
WP_156209982.1\|2157882_2158374_+	helix-turn-helix domain-containing protein	A0A1X9I723	Streptococcus_phage	1.1e-13	63.2
WP_156209983.1\|2158551_2159718_+\|integrase	tyrosine-type recombinase/integrase	A0A1X9I5Y5	Streptococcus_phage	9.9e-159	70.6
2159769:2159832	attR	NA	NA	NA	NA

DBSCAN-SWA_11

2170674 : 2182099

Staphylococcus_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014632484.1\|2170674_2171373_-	transglycosylase SLT domain-containing protein	Q4Z8Z7	Staphylococcus_phage	2.1e-26	68.8
WP_118185684.1\|2171556_2172129_-	LysM peptidoglycan-binding domain-containing protein	A0A288TY55	Enterococcus_phage	4.4e-19	78.0
WP_070655088.1\|2172429_2173224_-	energy-coupling factor transporter transmembrane protein EcfT	NA	NA	NA	NA
WP_014632481.1\|2173216_2174059_-	energy-coupling factor transporter ATPase	A0A2H4PQG7	Staphylococcus_phage	6.3e-14	27.9
WP_156209985.1\|2174034_2174865_-	energy-coupling factor transporter ATPase	G9BWD6	Planktothrix_phage	1.1e-21	32.7
WP_002885640.1\|2174877_2175420_-	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_156209986.1\|2175432_2176290_-	DUF4115 domain-containing protein	NA	NA	NA	NA
WP_156209987.1\|2176348_2177626_-	insulinase family protein	A0A2H4UVM3	Bodo_saltans_virus	3.7e-05	27.5
WP_156209988.1\|2177627_2178878_-	insulinase family protein	A0A1X9I714	Streptococcus_phage	1.5e-91	40.1
WP_156209989.1\|2178955_2179333_+	S4 domain-containing protein YaaA	A0A1X9I5V8	Streptococcus_phage	3.0e-24	72.4
WP_156209990.1\|2179335_2180436_+	DNA replication/repair protein RecF	NA	NA	NA	NA
WP_013991341.1\|2180617_2182099_-	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	2.6e-95	40.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP018186

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection