CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP046749	Vibrio cholerae strain 2015V-1118 chromosome 1, complete sequence	0 crisprs	DEDDh,DinG,csa3,WYL,cas3,csx1	0	0	3	0
NZ_CP046750	Vibrio cholerae strain 2015V-1118 chromosome 2, complete sequence	0 crisprs	RT,cas3,csa3	0	0	2	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

381664 : 388930

uncultured_Mediterranean_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_123162379.1\|381664_382456_+	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	8.4e-69	51.6
WP_000002982.1\|382448_383075_+	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	2.0e-36	52.1
WP_118089416.1\|383074_384010_+	murein hydrolase activator NlpD	D7RWE0	Brochothrix_phage	7.8e-05	34.7
WP_000116735.1\|384083_385091_+	RNA polymerase sigma factor RpoS	F4YCU2	Synechococcus_phage	6.0e-35	34.2
WP_001893275.1\|385186_387775_-	DNA mismatch repair protein MutS	A0A1V0SC35	Catovirus	5.8e-34	23.2
WP_001279365.1\|388042_388930_-	cysteine synthase CysM	A0A1X9I5K7	Streptococcus_phage	4.1e-56	41.1

DBSCAN-SWA_2

620363 : 627556

Faustovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000775249.1\|620363_621578_+	IscS subfamily cysteine desulfurase	A0A0H3TPH2	Faustovirus	8.8e-33	30.8
WP_000331703.1\|621614_621998_+	Fe-S cluster assembly scaffold IscU	A0A218MKD1	uncultured_virus	5.4e-53	78.2
WP_000301571.1\|622058_622382_+	iron-sulfur cluster assembly protein IscA	A0A2H4N7N5	Lake_Baikal_phage	3.0e-25	50.5
WP_001105750.1\|622430_622946_+	co-chaperone HscB	NA	NA	NA	NA
WP_123162432.1\|622969_624820_+	Fe-S protein assembly chaperone HscA	A0A0N9QXN8	Chrysochromulina_ericina_virus	7.0e-106	41.1
WP_001124187.1\|624833_625172_+	ISC system 2Fe-2S type ferredoxin	NA	NA	NA	NA
WP_000872174.1\|625220_625415_+	Fe-S cluster assembly protein IscX	NA	NA	NA	NA
WP_000107237.1\|625634_626924_+	aminopeptidase PepB	Q6GYZ8	Mycoplasma_phage	1.7e-34	34.3
WP_001162850.1\|627127_627556_+	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	1.0e-20	38.4

DBSCAN-SWA_3

2226399 : 2233015

Staphylococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_123162906.1\|2226399_2226870_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.2e-33	48.7
WP_123162907.1\|2227133_2228243_-	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	1.1e-63	39.8
WP_000493874.1\|2228283_2228937_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.2e-31	38.2
WP_123162908.1\|2228941_2230045_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	2.6e-44	33.3
WP_000543544.1\|2230070_2230520_-	transcriptional regulator NrdR	NA	NA	NA	NA
WP_080299252.1\|2230619_2231873_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	1.7e-100	49.7
WP_000210573.1\|2231881_2233015_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.4e-64	40.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP046750

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

143429 : 201882

Vibrio_phage(84.62%)

portal,terminase,tail,head,protease,capsid

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_123161927.1\|143429_146186_+\|protease	M6 family metalloprotease PrtV	NA	NA	NA	NA
WP_000717581.1\|146261_147116_-	lipase secretion chaperone	NA	NA	NA	NA
WP_001033424.1\|147125_148064_-	triacylglycerol lipase	NA	NA	NA	NA
WP_000586208.1\|148411_150058_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	1.5e-22	31.1
WP_001125272.1\|150358_152584_-	cytolysin VCC	NA	NA	NA	NA
WP_000746874.1\|153556_154813_+	thermolabile hemolysin	NA	NA	NA	NA
WP_000178904.1\|154933_156013_+	GGDEF domain-containing protein	A0A127AWB9	Bacillus_phage	4.4e-20	33.3
WP_000949610.1\|156003_156270_-	hypothetical protein	NA	NA	NA	NA
WP_001893346.1\|156483_157728_+	multidrug efflux MFS transporter EmrD	NA	NA	NA	NA
WP_123161928.1\|158122_159712_+	Na+/H+ antiporter NhaC family protein	NA	NA	NA	NA
WP_001905795.1\|159789_160839_-	hypothetical protein	NA	NA	NA	NA
WP_123161929.1\|161013_162960_+	ATP-binding protein	W8CYF6	Bacillus_phage	7.3e-05	23.3
WP_000362852.1\|163017_164559_-	DUF3369 domain-containing protein	NA	NA	NA	NA
WP_000717534.1\|164754_165282_-	nicotinate-nicotinamide nucleotide adenylyltransferase	NA	NA	NA	NA
WP_123161930.1\|165384_166215_+	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	8.3e-59	47.8
WP_123161931.1\|166465_167794_+	anaerobic C4-dicarboxylate transporter	NA	NA	NA	NA
WP_123161932.1\|167983_169378_+	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	4.5e-49	36.6
WP_123161934.1\|170926_172258_+	RNA-dependent DNA polymerase	NA	NA	NA	NA
WP_123161935.1\|173584_175216_-	hypothetical protein	A0A160DHT6	Vibrio_phage	2.5e-309	97.8
WP_000457681.1\|175212_175686_-	hypothetical protein	U3PDI0	Vibrio_phage	6.6e-77	100.0
WP_123161936.1\|175673_176567_-	hypothetical protein	U3PIM3	Vibrio_phage	3.2e-157	97.6
WP_123161937.1\|176569_177100_-	hypothetical protein	A9ZT45	Vibrio_virus	6.5e-41	76.8
WP_000005871.1\|178672_179332_-	hypothetical protein	U3PB79	Vibrio_phage	1.2e-124	99.1
WP_123161938.1\|179328_180528_-	hypothetical protein	U3PDH5	Vibrio_phage	1.9e-221	99.2
WP_123161939.1\|180524_180857_-	DUF2590 family protein	U3PIM1	Vibrio_phage	3.8e-55	99.1
WP_123161940.1\|180846_182664_-\|tail	phage tail tape measure protein	U3PFL8	Vibrio_phage	2.5e-265	81.0
WP_000165783.1\|182860_183142_-	hypothetical protein	A0A160DHS7	Vibrio_phage	5.3e-34	76.3
WP_114813176.1\|183349_183691_-	hypothetical protein	U3PB75	Vibrio_phage	6.4e-50	96.5
WP_123161942.1\|183665_184253_-	lysozyme	U3PDH1	Vibrio_phage	5.6e-110	99.5
WP_001899725.1\|184239_184452_-	hypothetical protein	U3PIL8	Vibrio_phage	5.6e-28	85.5
WP_114742987.1\|184448_184658_-	TraR/DksA family transcriptional regulator	U3PFL5	Vibrio_phage	1.5e-28	89.6
WP_123161943.1\|184672_185131_-	DUF2597 family protein	U3PCG7	Vibrio_phage	3.3e-81	97.4
WP_123161944.1\|185130_186240_-	DUF2586 family protein	U3PB71	Vibrio_phage	2.3e-205	98.1
WP_123161945.1\|186241_186901_-	phage virion morphogenesis protein	U3PDG7	Vibrio_phage	5.0e-115	98.2
WP_114813168.1\|186887_187376_-	hypothetical protein	U3PIL4	Vibrio_phage	2.7e-89	99.4
WP_061051036.1\|187372_187834_-\|head	head completion/stabilization protein	U3PFL1	Vibrio_phage	5.8e-78	99.3
WP_123161946.1\|187940_188663_-\|terminase	terminase endonuclease subunit	U3PCG2	Vibrio_phage	3.3e-120	93.0
WP_000930691.1\|188673_189675_-\|capsid	phage major capsid protein, P2 family	R9TPZ5	Vibrio_phage	1.5e-107	61.9
WP_123161947.1\|189674_190562_-\|capsid	capsid protein	R9TRS3	Vibrio_phage	1.2e-95	63.5
WP_123161948.1\|190735_192556_+\|terminase	terminase ATPase subunit family protein	U3PIL1	Vibrio_phage	0.0e+00	94.4
WP_123162261.1\|192552_193575_+\|portal	phage portal protein	U3PFK6	Vibrio_phage	6.8e-188	92.9
WP_123161949.1\|193838_194408_+	DUF4760 domain-containing protein	Q8HA56	Vibrio_phage	1.8e-25	38.1
WP_123161950.1\|194497_194749_+	ogr/Delta-like zinc finger family protein	Q8HA63	Vibrio_phage	2.1e-42	97.6
WP_123161951.1\|194743_194962_-	hypothetical protein	Q8HA64	Vibrio_phage	5.6e-31	100.0
WP_123161952.1\|195161_197747_-	replication endonuclease	A0A166YHE2	Vibrio_phage	0.0e+00	98.1
WP_123161953.1\|197785_198073_+	hypothetical protein	NA	NA	NA	NA
WP_001198812.1\|198271_198499_-	hypothetical protein	U3PIK2	Vibrio_phage	2.6e-23	61.3
WP_123161955.1\|198748_199159_-	hypothetical protein	U3PCE8	Vibrio_phage	1.3e-73	97.8
WP_123161956.1\|199155_199671_-	hypothetical protein	U3PB56	Vibrio_phage	7.3e-29	51.4
WP_123161957.1\|199751_200186_-	hypothetical protein	U3PDF0	Vibrio_phage	1.4e-73	99.3
WP_000253094.1\|200198_200738_-	hypothetical protein	U3PIJ8	Vibrio_phage	1.0e-94	98.9
WP_000959091.1\|200848_201061_-	hypothetical protein	U3PFJ1	Vibrio_phage	3.2e-23	78.6
WP_123161958.1\|201228_201882_+	phage repressor protein CI	A0A166YHA0	Vibrio_phage	1.0e-80	71.9

DBSCAN-SWA_2

784053 : 816897

Vibrio_phage(36.0%)

integrase,transposase

attL 786029:786044|attR 816323:816338

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_148039557.1\|784053_785466_-	hypothetical protein	H9EB45	Vibrio_phage	4.2e-26	23.5
WP_123162136.1\|785696_786575_-	hypothetical protein	NA	NA	NA	NA
786029:786044	attL	NA	NA	NA	NA
WP_123162137.1\|786577_787438_-	hypothetical protein	A0A1B0Z0D6	Vibrio_phage	5.6e-42	37.4
WP_123162138.1\|787438_790396_-	tape measure protein	A0A2I2L6P9	Escherichia_phage	1.3e-16	22.8
WP_001200696.1\|790392_790722_-	hypothetical protein	NA	NA	NA	NA
WP_123162139.1\|790727_791060_-	hypothetical protein	NA	NA	NA	NA
WP_123162140.1\|791098_792016_-	hypothetical protein	G8EY04	Synechococcus_phage	1.0e-33	34.1
WP_001050344.1\|792025_792463_-	hypothetical protein	NA	NA	NA	NA
WP_123162141.1\|792474_792879_-	DUF1320 domain-containing protein	A0A2I7S9E9	Vibrio_phage	1.8e-06	33.1
WP_148039558.1\|792881_793313_-	hypothetical protein	A0A0C4UQZ0	Shigella_phage	2.5e-06	31.0
WP_123162143.1\|793369_794269_-	hypothetical protein	J9SVY7	Pseudomonas_phage	6.6e-78	46.6
WP_123162144.1\|794271_794658_-	hypothetical protein	NA	NA	NA	NA
WP_123162145.1\|794659_795769_-	hypothetical protein	A0A0C4UQU6	Shigella_phage	1.1e-63	42.3
WP_123162146.1\|795841_797143_-	hypothetical protein	NA	NA	NA	NA
WP_000929398.1\|797374_797833_-	phage virion morphogenesis protein	J9SNH3	Pseudomonas_phage	1.4e-20	36.4
WP_000039943.1\|797832_798024_-	hypothetical protein	NA	NA	NA	NA
WP_123162147.1\|798036_799452_-	F protein	A0A2H4IYU7	uncultured_Caudovirales_phage	5.9e-65	48.8
WP_123162148.1\|799451_800999_-	DUF935 domain-containing protein	J9SVY0	Pseudomonas_phage	1.1e-128	49.7
WP_123162149.1\|801007_802561_-	hypothetical protein	A0A2I7S9C5	Vibrio_phage	5.0e-166	62.3
WP_123162150.1\|802560_803139_-	DUF3486 family protein	NA	NA	NA	NA
WP_001162663.1\|803147_803438_-	hypothetical protein	A0A2I7S9D8	Vibrio_phage	5.0e-27	65.3
WP_000801962.1\|803437_803773_-	DUF2730 family protein	NA	NA	NA	NA
WP_123162151.1\|803781_803985_-	TraR/DksA family transcriptional regulator	NA	NA	NA	NA
WP_123162152.1\|803981_804581_-	hypothetical protein	M4MB79	Vibrio_phage	1.3e-42	59.4
WP_001259553.1\|804829_805267_-	hypothetical protein	M4M9N1	Vibrio_phage	3.5e-48	60.7
WP_123162153.1\|805475_805886_-	transcriptional regulator	A0A0C4UQZ9	Shigella_phage	9.2e-19	38.0
WP_123162154.1\|806092_807142_-	AAA family ATPase	Q7M293	Enterobacteria_phage	2.0e-25	29.4
WP_123162155.1\|807366_807942_-	regulatory protein GemA	A0A0C4UQU3	Shigella_phage	5.1e-31	37.8
WP_123162156.1\|808106_808328_-	hypothetical protein	A0A2I7S9C8	Vibrio_phage	1.1e-07	68.9
WP_000749526.1\|808413_808623_-	ANR family transcriptional regulator	NA	NA	NA	NA
WP_000172412.1\|808648_809275_-	DUF3164 family protein	M4MHH7	Vibrio_phage	1.3e-64	64.0
WP_123162157.1\|809271_809460_-	hypothetical protein	NA	NA	NA	NA
WP_000368744.1\|809444_809696_-	hypothetical protein	NA	NA	NA	NA
WP_119773028.1\|809756_810302_-	helix-turn-helix transcriptional regulator	A0A1B0T6G8	Thiobacimonas_phage	3.7e-07	32.3
WP_123162158.1\|810285_810879_-	hypothetical protein	NA	NA	NA	NA
WP_000791090.1\|810890_811622_-	ATP-binding protein	A0A1B0T6H3	Thiobacimonas_phage	8.7e-20	30.2
WP_123162159.1\|811755_814002_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	M4T586	Rhodobacter_phage	2.4e-44	24.2
WP_123162161.1\|814476_815154_+	XRE family transcriptional regulator	A0A1C6ZDG7	Pseudomonas_phage	2.1e-23	30.9
WP_000684072.1\|815730_816897_+	nucleotide sugar dehydrogenase	M1HZB2	Paramecium_bursaria_Chlorella_virus	5.5e-109	52.4
816323:816338	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP046749

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP046750

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection