CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP046844	Vibrio cholerae C6706 chromosome 1, complete sequence	0 crisprs	csa3,DEDDh,cas3,WYL,DinG,csx1,RT	0	0	7	0
NZ_CP046845	Vibrio cholerae C6706 chromosome 2, complete sequence	0 crisprs	PD-DExK,cas3,csa3	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

99933 : 108551

Vibrio_phage(33.33%)

integrase,tRNA,transposase

attL 101013:101025|attR 107660:107672

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_100068541.1\|99933_101110_+\|transposase	IS3 family transposase	Q716C2	Shigella_phage	8.6e-118	65.1
101013:101025	attL	NA	NA	NA	NA
WP_001129565.1\|101146_102388_-\|integrase	tyrosine-type recombinase/integrase	A0A1V0E8G8	Vibrio_phage	9.1e-110	47.3
WP_000372618.1\|102773_104651_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.5e-34	32.9
WP_000907210.1\|104749_106513_-	DNA primase	A0A1S5RG58	Helicobacter_phage	1.1e-44	30.7
WP_001173892.1\|106602_107046_-	GatB/YqeY domain-containing protein	A0A292GL36	Xanthomonas_phage	3.7e-29	49.3
WP_001145625.1\|107075_107291_-	30S ribosomal protein S21	NA	NA	NA	NA
WP_001220122.1\|107531_108551_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	2.6e-107	57.4
107660:107672	attR	NA	NA	NA	NA

DBSCAN-SWA_2

114681 : 121944

uncultured_Mediterranean_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001883363.1\|114681_115473_+	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	8.4e-69	51.6
WP_000002982.1\|115465_116092_+	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	2.0e-36	52.1
WP_000177568.1\|116091_117027_+	murein hydrolase activator NlpD	D7RWE0	Brochothrix_phage	7.8e-05	34.7
WP_000116737.1\|117100_118108_+	RNA polymerase sigma factor RpoS	F4YCU2	Synechococcus_phage	6.0e-35	34.2
WP_001894770.1\|118200_120789_-	DNA mismatch repair protein MutS	A0A1V0SC35	Catovirus	2.2e-33	23.0
WP_001279365.1\|121056_121944_-	cysteine synthase CysM	A0A1X9I5K7	Streptococcus_phage	4.1e-56	41.1

DBSCAN-SWA_3

353573 : 360766

Faustovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000775253.1\|353573_354788_+	IscS subfamily cysteine desulfurase	A0A0H3TPH2	Faustovirus	1.1e-32	30.5
WP_000331703.1\|354824_355208_+	Fe-S cluster assembly scaffold IscU	A0A218MKD1	uncultured_virus	5.4e-53	78.2
WP_000301571.1\|355268_355592_+	iron-sulfur cluster assembly protein IscA	A0A2H4N7N5	Lake_Baikal_phage	3.0e-25	50.5
WP_001105747.1\|355640_356156_+	co-chaperone HscB	NA	NA	NA	NA
WP_001196560.1\|356179_358030_+	Fe-S protein assembly chaperone HscA	A0A0N9QXN8	Chrysochromulina_ericina_virus	5.3e-106	41.1
WP_001124187.1\|358043_358382_+	ISC system 2Fe-2S type ferredoxin	NA	NA	NA	NA
WP_000872176.1\|358430_358625_+	Fe-S cluster assembly protein IscX	NA	NA	NA	NA
WP_000107237.1\|358844_360134_+	aminopeptidase PepB	Q6GYZ8	Mycoplasma_phage	1.7e-34	34.3
WP_001162850.1\|360337_360766_+	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	1.0e-20	38.4

DBSCAN-SWA_4

1099751 : 1132369

Vibrio_phage(47.37%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_149591715.1\|1099751_1101857_-	RTX toxin T1SS ABC transporter subunit RtxB	W8CYL7	Bacillus_phage	4.9e-39	27.1
WP_000514481.1\|1102271_1102631_+	hypothetical protein	NA	NA	NA	NA
WP_001881196.1\|1102656_1103118_+	RTX toxin-activating lysine-acyltransferase RtxC	NA	NA	NA	NA
WP_001881197.1\|1103102_1116779_+	MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin RtxA	B3Y8K3	Vibrio_virus	8.4e-07	100.0
WP_000053920.1\|1117146_1117371_-	RstC protein	U5TMI6	Satellite_phage	1.1e-34	100.0
WP_010895442.1\|1117464_1117839_-	hypothetical protein	B9V3G5	Vibrio_virus	1.2e-68	100.0
WP_000743997.1\|1117816_1118896_-	hypothetical protein	U5TQR3	Satellite_phage	2.2e-213	100.0
WP_000693566.1\|1119021_1119360_+	helix-turn-helix transcriptional regulator	U5TNA1	Satellite_phage	7.3e-54	100.0
WP_000593522.1\|1119972_1120347_-	cholera enterotoxin binding subunit CtxB	Q77DH7	Vibrio_virus	7.8e-65	100.0
WP_001881225.1\|1120343_1121120_-	cholera enterotoxin catalytic subunit CtxA	A0A142I6Y0	Vibrio_phage	1.3e-151	100.0
WP_000021616.1\|1121218_1122418_-	zonula occludens toxin ZOT	A0A142I6Z1	Vibrio_phage	5.3e-240	100.0
WP_000979342.1\|1122414_1122708_-	accessory cholera enterotoxin	A0A0F6YNQ7	Vibrio_phage	3.7e-46	100.0
WP_001881237.1\|1122704_1123988_-	hypothetical protein	A0A142I701	Vibrio_phage	9.1e-222	100.0
WP_000493022.1\|1123998_1124247_-	colonization factor	A0A0N7F140	Vibrio_phage	8.8e-33	100.0
WP_001888513.1\|1124382_1124763_-	hypothetical protein	A0A0N9HJ67	Vibrio_phage	4.0e-69	100.0
WP_000743997.1\|1124740_1125820_-	hypothetical protein	U5TQR3	Satellite_phage	2.2e-213	100.0
WP_000693566.1\|1125945_1126284_+	helix-turn-helix transcriptional regulator	U5TNA1	Satellite_phage	7.3e-54	100.0
WP_000170634.1\|1126773_1127358_-	DNA-binding protein	E3U9I9	Vibrio_phage	6.4e-114	100.0
WP_001161489.1\|1127350_1127518_-	hypothetical protein	E3U9J0	Vibrio_phage	2.3e-13	100.0
WP_001052672.1\|1127595_1128288_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_001881265.1\|1128417_1128702_-	hypothetical protein	NA	NA	NA	NA
WP_001881266.1\|1128706_1130275_-	replication protein	A7BJY2	Enterobacteria_phage	2.7e-58	32.3
WP_001265358.1\|1130436_1131003_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000170632.1\|1132041_1132209_-	hypothetical protein	NA	NA	NA	NA
WP_001161489.1\|1132201_1132369_-	hypothetical protein	E3U9J0	Vibrio_phage	2.3e-13	100.0

DBSCAN-SWA_5

1141013 : 1191219

Vibrio_phage(46.67%)

head,terminase,transposase,portal,capsid,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_086026889.1\|1141013_1142235_+\|transposase	IS3-like element ISVch4 family transposase	Q716C2	Shigella_phage	1.5e-117	65.1
WP_001881271.1\|1143144_1143504_-	hypothetical protein	E3U9J1	Vibrio_phage	7.6e-09	100.0
WP_001881272.1\|1143614_1143947_-	DUF3634 family protein	NA	NA	NA	NA
WP_000877146.1\|1143951_1144401_-	macrodomain Ter protein MatP	NA	NA	NA	NA
WP_001881274.1\|1144417_1146214_+\|protease	Lon protease family protein	NA	NA	NA	NA
WP_001180252.1\|1146278_1146797_+	bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase	NA	NA	NA	NA
WP_001881287.1\|1146879_1147053_-	ribosome modulation factor	NA	NA	NA	NA
WP_000087036.1\|1147220_1148915_-	DUF3466 family protein	NA	NA	NA	NA
WP_001174034.1\|1148920_1150840_-	ABC transporter ATP-binding protein	A0A2K9L3Z8	Tupanvirus	7.6e-55	29.7
WP_000631987.1\|1150817_1151060_-	glutaredoxin family protein	NA	NA	NA	NA
WP_001077794.1\|1151068_1153195_-	bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL	NA	NA	NA	NA
WP_000917529.1\|1153654_1154197_-	cell division protein ZapC	NA	NA	NA	NA
WP_000966885.1\|1154351_1155362_-	quinone-dependent dihydroorotate dehydrogenase	NA	NA	NA	NA
WP_000126926.1\|1155435_1160277_-	NAD-glutamate dehydrogenase	NA	NA	NA	NA
WP_001881297.1\|1160465_1160702_-	DUF2835 domain-containing protein	NA	NA	NA	NA
WP_000377996.1\|1160735_1163360_-	aminopeptidase N	NA	NA	NA	NA
WP_001994019.1\|1163432_1163669_-	ArsR family transcriptional regulator	NA	NA	NA	NA
WP_001241333.1\|1164617_1165130_+	hypothetical protein	NA	NA	NA	NA
WP_001912825.1\|1165446_1166712_+	ATP-binding protein	NA	NA	NA	NA
WP_000347185.1\|1166713_1167136_+	hypothetical protein	NA	NA	NA	NA
WP_000092362.1\|1167199_1167565_-	peptidase M15	A0A2I7RAT1	Vibrio_phage	8.7e-37	60.3
WP_000279700.1\|1167548_1168106_-	hypothetical protein	NA	NA	NA	NA
WP_000291407.1\|1168105_1169113_-	radical SAM protein	NA	NA	NA	NA
WP_001005176.1\|1169129_1169495_-	hypothetical protein	C8ZKF3	Pseudomonas_phage	1.8e-05	46.2
WP_000521739.1\|1169495_1175438_-	fibronectin type III domain-containing protein	M4MHT9	Vibrio_phage	2.0e-98	30.9
WP_000491559.1\|1175441_1175837_-	hypothetical protein	NA	NA	NA	NA
WP_000168946.1\|1175839_1176379_-	hypothetical protein	M4MD40	Vibrio_phage	4.5e-21	35.1
WP_000250921.1\|1176389_1176971_-	hypothetical protein	NA	NA	NA	NA
WP_000907543.1\|1176972_1179285_-	hypothetical protein	A0A1Q1PW43	Pseudoalteromonas_phage	4.4e-09	22.6
WP_000967642.1\|1179301_1179592_-	hypothetical protein	NA	NA	NA	NA
WP_001081280.1\|1179636_1179972_-	hypothetical protein	NA	NA	NA	NA
WP_000907300.1\|1180024_1180495_-	hypothetical protein	NA	NA	NA	NA
WP_001994025.1\|1180508_1180832_-	hypothetical protein	NA	NA	NA	NA
WP_000049624.1\|1180879_1181491_-	hypothetical protein	NA	NA	NA	NA
WP_001252475.1\|1181477_1181825_-	hypothetical protein	NA	NA	NA	NA
WP_000020008.1\|1181836_1182388_-	hypothetical protein	A0A2I7QU98	Vibrio_phage	8.9e-09	28.0
WP_000667008.1\|1182402_1183593_-\|capsid	phage major capsid protein	M4MA06	Vibrio_phage	1.3e-36	33.3
WP_000944879.1\|1183691_1184540_-\|head,protease	HK97 family phage prohead protease	Q6JIM8	Burkholderia_virus	7.0e-29	39.1
WP_000523754.1\|1184502_1185828_-\|portal	phage portal protein	M4MHV5	Vibrio_phage	1.2e-75	38.9
WP_001070130.1\|1185837_1187598_-\|terminase	terminase large subunit	A0A0K1LKI4	Staphylococcus_phage	1.1e-81	35.9
WP_000165579.1\|1187788_1188004_-	hypothetical protein	NA	NA	NA	NA
WP_001046237.1\|1188031_1188712_-	hypothetical protein	NA	NA	NA	NA
WP_001994028.1\|1188708_1189152_-	hypothetical protein	NA	NA	NA	NA
WP_080004477.1\|1189294_1189705_-\|terminase	phage terminase small subunit P27 family	A0A1W6JP17	Morganella_phage	5.8e-05	31.6
WP_000243876.1\|1190175_1190364_-	hypothetical protein	NA	NA	NA	NA
WP_000858033.1\|1190574_1191219_+	antirestriction protein	G0YPX7	Erwinia_phage	1.1e-10	33.5

DBSCAN-SWA_6

1195874 : 1203601

Diadromus_pulchellus_ascovirus(14.29%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001146354.1\|1195874_1196462_-	AAA family ATPase	F2NYY4	Diadromus_pulchellus_ascovirus	2.1e-08	33.1
WP_000576446.1\|1196481_1196751_-	hypothetical protein	NA	NA	NA	NA
WP_000275003.1\|1196955_1197549_-	AAA family ATPase	A0A249Y6S3	Cherax_quadricarinatus_iridovirus	3.7e-08	30.0
WP_000784089.1\|1197681_1197939_-	hypothetical protein	NA	NA	NA	NA
WP_001912807.1\|1197935_1198220_-	hypothetical protein	A0A142K9B6	Gordonia_phage	3.9e-08	51.9
WP_001044551.1\|1198402_1199263_-	exonuclease	F1D0G7	Vibrio_phage	3.1e-56	43.0
WP_000467314.1\|1199456_1199888_-	tellurite resistance TerB family protein	Q1MVI3	Enterobacteria_phage	2.1e-29	47.9
WP_000983185.1\|1199912_1201967_-	hypothetical protein	A0A0F7DD46	Delftia_phage	7.1e-144	40.8
WP_000046513.1\|1201966_1203601_-	toprim domain-containing protein	L7TLT7	Rhizobium_phage	1.6e-122	49.0

DBSCAN-SWA_7

2028213 : 2034830

Staphylococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000864130.1\|2028213_2028684_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	6.8e-34	48.7
WP_001122865.1\|2028948_2030058_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	6.7e-64	39.8
WP_000493874.1\|2030098_2030752_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.2e-31	38.2
WP_001131994.1\|2030756_2031860_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	1.3e-43	33.1
WP_000543544.1\|2031885_2032335_-	transcriptional regulator NrdR	NA	NA	NA	NA
WP_001890340.1\|2032434_2033688_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	5.0e-100	49.5
WP_000210573.1\|2033696_2034830_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.4e-64	40.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage