CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP043848	Staphylococcus epidermidis strain NCCP 16828 plasmid unnamed, complete sequence	0 crisprs	NA	0	0	0	0
NZ_CP043847	Staphylococcus epidermidis strain NCCP 16828 chromosome, complete genome	6 crisprs	DinG,DEDDh,cas3,csa3,WYL	0	3	6	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP043847_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP043847_1

172673-172757

Orphan

Consensus_repeat	Method
AGACAAGGCAAGTTGGGGTTCGGGGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP043847_1

>merge|NZ_CP043847|1|172673-172757|CRISPRCasFinder
AGACAAGGCAAGTTGGGGTTCGGGGCCCCAACAAAAAGAATTTCACCGAGAAATTCAAAAGACAAGGCGAGTTGGGGTTCGGGGC

>NZ_CP043847|1|1|172673-172757|CRISPRCasFinder
AGACAAGGCAAGTTGGGGTTCGGGGC	CCCAACAAAAAGAATTTCACCGAGAAATTCAAA
AGACAAGGCGAGTTGGGGTTCGGGGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP043847.1\|WP_017464986.1\|168593_169520_+\|hydroxymethylbilane-synthase	unknown	unknown	gnl\|CDD\|234612
NZ_CP043847.1\|WP_002446629.1\|180531_180711_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043847.1\|WP_017464984.1\|165602_166190_+\|YihA-family-ribosome-biogenesis-GTP-binding-protein	unknown	unknown	gnl\|CDD\|234770
NZ_CP043847.1\|WP_001830756.1\|181444_181585_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043847.1\|WP_002474761.1\|174087_174648_-\|DNA-3-methyladenine-glycosylase-I	unknown	unknown	gnl\|CDD\|377025
NZ_CP043847.1\|WP_074838394.1\|181981_182830_+\|rod-shape-determining-protein-MreC	unknown	unknown	gnl\|CDD\|237560
NZ_CP043847.1\|WP_017464982.1\|161557_162481_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|211334
NZ_CP043847.1\|WP_002440172.1\|177631_178897_+\|bifunctional-folylpolyglutamate-synthase/dihydrofolate-synthase	unknown	unknown	gnl\|CDD\|223362
NZ_CP043847.1\|WP_002497969.1\|171221_172505_+\|glutamate-1-semialdehyde-2,1-aminomutase	unknown	unknown	gnl\|CDD\|234607
NZ_CP043847.1\|WP_158171693.1\|172853_173921_+\|AbrB-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|377472
NZ_CP043847.1\|WP_001832708.1\|180875_181361_+\|DUF4930-family-protein	unknown	unknown	gnl\|CDD\|374471
NZ_CP043847.1\|WP_002474751.1\|169553_170234_+\|uroporphyrinogen-III-synthase	unknown	unknown	gnl\|CDD\|119440
NZ_CP043847.1\|WP_002474752.1\|179787_180468_+\|JAB-domain-containing-protein	unknown	unknown	gnl\|CDD\|178801
NZ_CP043847.1\|WP_145355167.1\|162640_163942_+\|trigger-factor	unknown	unknown	gnl\|CDD\|234956
NZ_CP043847.1\|WP_017464988.1\|179080_179791_+\|prepilin-peptidase	unknown	unknown	gnl\|CDD\|377700
NZ_CP043847.1\|WP_002474770.1\|167727_168540_+\|cytochrome-c-assembly-protein	unknown	unknown	gnl\|CDD\|223826
NZ_CP043847.1\|WP_001830765.1\|164228_165491_+\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpX	unknown	unknown	gnl\|CDD\|235422
NZ_CP043847.1\|WP_001830773.1\|166359_167706_+\|glutamyl-tRNA-reductase	unknown	unknown	gnl\|CDD\|234592
NZ_CP043847.1\|WP_002474755.1\|170223_171198_+\|porphobilinogen-synthase	unknown	unknown	gnl\|CDD\|236450
NZ_CP043847.1\|WP_158171694.1\|174990_177621_+\|valine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235582

Protein	Function_ID	Function_description	E-value
NZ_CP043847.1\|WP_017464986.1\|168593_169520_+\|hydroxymethylbilane-synthase	gnl\|CDD\|234612	PRK00072, hemC, porphobilinogen deaminase; Reviewed.	1.53537e-160
NZ_CP043847.1\|WP_017464984.1\|165602_166190_+\|YihA-family-ribosome-biogenesis-GTP-binding-protein	gnl\|CDD\|234770	PRK00454, engB, GTP-binding protein YsxC; Reviewed.	4.86551e-97
NZ_CP043847.1\|WP_002474761.1\|174087_174648_-\|DNA-3-methyladenine-glycosylase-I	gnl\|CDD\|377025	pfam03352, Adenine_glyco, Methyladenine glycosylase. The DNA-3-methyladenine glycosylase I is constitutively expressed and is specific for the alkylated 3-methyladenine DNA.	2.79865e-87
NZ_CP043847.1\|WP_074838394.1\|181981_182830_+\|rod-shape-determining-protein-MreC	gnl\|CDD\|237560	PRK13922, PRK13922, rod shape-determining protein MreC; Provisional.	8.07911e-74
NZ_CP043847.1\|WP_017464982.1\|161557_162481_+\|hypothetical-protein	gnl\|CDD\|211334	cd02566, PseudoU_synth_RluE, Pseudouridine synthase, Escherichia coli RluE. This group is comprised of bacterial proteins similar to E. coli RluE. Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi). No cofactors are required. Escherichia coli RluE makes psi2457 in 23S RNA. psi2457 is not universally conserved.	0.00936292
NZ_CP043847.1\|WP_002440172.1\|177631_178897_+\|bifunctional-folylpolyglutamate-synthase/dihydrofolate-synthase	gnl\|CDD\|223362	COG0285, FolC, Folylpolyglutamate synthase [Coenzyme metabolism].	1.80605e-143
NZ_CP043847.1\|WP_002497969.1\|171221_172505_+\|glutamate-1-semialdehyde-2,1-aminomutase	gnl\|CDD\|234607	PRK00062, PRK00062, glutamate-1-semialdehyde 2,1-aminomutase.	0
NZ_CP043847.1\|WP_158171693.1\|172853_173921_+\|AbrB-family-transcriptional-regulator	gnl\|CDD\|377472	pfam05145, AbrB, Transition state regulatory protein AbrB. Bacillus subtilis respond to a multitude of environmental stimuli by using transcription factors called transition state regulators (TSRs). They play an essential role in cell survival by regulating spore formation, competence, and biofilm development. AbrB is one of the most known TSRs, acting as a pleotropic regulator for over 60 different genes where it directly binds to their promoter or regulatory regions. Many other genes are indirectly controlled by AbrB since it is a regulator of other regulatory proteins, including ScoC, Abh, SinR and SigH. Hence, AbrB is considered a global regulatory protein controlling processes such as Bacillus subtilis growth and cell division as well as production of extracellular degradative enzymes, nitrogen utilization and amino acid metabolism, motility, synthesis of antibiotics and their resistant determinants, development of competence, transport systems, oxidative stress response, phosphate metabolism, cell surface components and sporulation. AbrB is a tetramer consisting of identical 94 residue monomers. Its DNA-binding function resides solely in the N-terminal domain (AbrBN) of 53 residues. Although it does not recognize a well-defined DNA base-pairing sequence, instead, it appears to target a very weak pseudo consensus nucleotide sequence, TGGNA-5bp-TGGNA, which allows it to be rather promiscuous in binding. The N-terminal domains of very similar sequences are present in two more Bacillus subtilis proteins, Abh and SpoVT. Mutagenesis studies suggest that the role of the C-terminal domain is in forming multimers.	4.12819e-70
NZ_CP043847.1\|WP_001832708.1\|180875_181361_+\|DUF4930-family-protein	gnl\|CDD\|374471	pfam16284, DUF4930, Domain of unknown function (DUF4930). A small family of uncharacterized proteins around 150 residues in length and found in various Staphylococcus aureus species. The function of this family is unknown.	3.2927e-76
NZ_CP043847.1\|WP_002474751.1\|169553_170234_+\|uroporphyrinogen-III-synthase	gnl\|CDD\|119440	cd06578, HemD, Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in the human uroporphyrinogen-III synthase gene cause congenital erythropoietic porphyria, a recessive inborn error of metabolism also known as Gunther disease.	3.95089e-42
NZ_CP043847.1\|WP_002474752.1\|179787_180468_+\|JAB-domain-containing-protein	gnl\|CDD\|178801	PRK00024, PRK00024, DNA repair protein RadC.	2.63762e-108
NZ_CP043847.1\|WP_145355167.1\|162640_163942_+\|trigger-factor	gnl\|CDD\|234956	PRK01490, tig, trigger factor; Provisional.	7.42371e-162
NZ_CP043847.1\|WP_017464988.1\|179080_179791_+\|prepilin-peptidase	gnl\|CDD\|377700	pfam06750, DiS_P_DiS, Bacterial Peptidase A24 N-terminal domain. This family is found at the N-terminus of the pre-pilin peptidases (pfam01478). It's function has not been specifically determined; however some of the family have been characterized as bifunctional, and this domain may contain the N-methylation activity (EC:2.1.1.-). It consists of an intracellular region between a pair of transmembrane. This region contains an invariant proline and two almost fully conserved disulphide bridges - hence the name DiS-P-DiS. The cysteines have been shown to be essential to the overall function of the enzyme in, but their role was incorrectly ascribed.	1.47956e-14
NZ_CP043847.1\|WP_002474770.1\|167727_168540_+\|cytochrome-c-assembly-protein	gnl\|CDD\|223826	COG0755, CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component [Posttranslational modification, protein turnover, chaperones].	9.56288e-21
NZ_CP043847.1\|WP_001830765.1\|164228_165491_+\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpX	gnl\|CDD\|235422	PRK05342, clpX, ATP-dependent Clp protease ATP-binding subunit ClpX.	0
NZ_CP043847.1\|WP_001830773.1\|166359_167706_+\|glutamyl-tRNA-reductase	gnl\|CDD\|234592	PRK00045, hemA, glutamyl-tRNA reductase; Reviewed.	0
NZ_CP043847.1\|WP_002474755.1\|170223_171198_+\|porphobilinogen-synthase	gnl\|CDD\|236450	PRK09283, PRK09283, porphobilinogen synthase.	0
NZ_CP043847.1\|WP_158171694.1\|174990_177621_+\|valine--tRNA-ligase	gnl\|CDD\|235582	PRK05729, valS, valyl-tRNA synthetase; Reviewed.	0

>NZ_CP043847.1|WP_002497969.1|171221_172505_+|glutamate-1-semialdehyde-2,1-aminomutase
MSFEKSIKAMEQAEKLMPGGVNSPVRAFKSVDTPAIFMDHGEGSKIYDIDGNEYIDYVLSWGPLILGHKNQQVISKLHEAVDKGTSFGASTLQENKLAELVIDRVPSIEKVRMVSSGTEATLDTLRLARGYTGRNKIIKFEGCYHGHSDSLLIKAGSGVATLGLPDSPGVPEGIAKNTITVPYNDLDSLKLAFEKYGDDIAGVIVEPVAGNMGVVPPVDGFLQGLRDITTEYGALLIFDEVMTGFRVGYNCAQGYFGVTPDLTCLGKVIGGGLPVGAFGGKKEIMDYIAPVGTIYQAGTLSGNPLAMTSGYETLSQLTPESYEYFNSLGDLLEKGLKEVFAKHNVPITVNRAGSMIGYFLNEGPVTNFEEANKSDLKLFSNMYREMAKEGVFLPPSQFEGTFLSTAHTKDDIEKTIQAFDNALSRIV
>NZ_CP043847.1|WP_002474755.1|170223_171198_+|porphobilinogen-synthase
MKFDRHRRLRSSKTMRDLVRETHVRKEDLIYPIFVVEQDDIKSEIKSLPGVYQISLNLLHEEIKEAYDLGIRAIMFFGVPNDKDDIGSGAYDHNGVVQEATRISKNLYKDLLIVADTCLCEYTDHGHCGVIDDHTHDVDNDKSLPLLVKTAISQVEAGADIIAPSNMMDGFVAEIREGLDQAGYQNIPIMSYGIKYASSFFGPFRDAADSAPSFGDRKTYQMDPANRLEALRELESDLKEGCDMMIVKPSLSYLDIIRDVKNNTNVPVVAYNVSGEYSMTKAAALNGWIDEEKIVMEQMISMKRAGADLIITYFAKDICRYLDK
>NZ_CP043847.1|WP_002474751.1|169553_170234_+|uroporphyrinogen-III-synthase
MKPVIVMTQTNEVHSHLVDIIHKPFIQLKQLHFNEKLLDHSYDWLIFSSKNAVKYFYPYLKNVKVKKVAVIGDKTAEYCNELGISVDFVPRDFSQEGFLDEFKISEQHLLLPSSEKARPKLVQQLSKYNEVAKIDLYRPVPNFKNISQVKSLVRKHQIDAVTFSSSSAVEFYFKEDNVPEFDHYFAIGKQTARTILKFNASVKVANKQTLDSLIDKIIESREQNEI
>NZ_CP043847.1|WP_017464986.1|168593_169520_+|hydroxymethylbilane-synthase
MRKLIVGSRRSKLALTQSQQFIDKLKLIDPSLDIEIKEIVTKGDKIVDKQLSKVGGKGLFVKEIQNELFNKEIDMAIHSLKDVPSMIPDGLTLGCIPDREIPFDAYIAKNHIPLQELSEGSIVGTSSLRRGAQILSKYPHLKIKWIRGNIDTRLKKLQTEDYDAIILAAAGLKRMGWSDNIVTTYLDRYILLPAIGQGALGIECRSDDKELLDLLSKVHNHDVAQCVTAERTFLSEMDGSCQVPIGGYATIAQDNQIEFTGLIMSPDGKERYEHTVLGTDPVKLGKEVSQVLKKQGAYDIIKKLNEAE
>NZ_CP043847.1|WP_002474770.1|167727_168540_+|cytochrome-c-assembly-protein
MQETLLIRFHEIILMIYLFSIICYFVDFINKNYKTRTVGFYSLGIVWVLQTISLSIFFIHTKQVPLGSIFDVFFSLTWIIISISLILNLIKVMNFSVFFLNLIGFILMSLNTFQPEHYQTQIQQIAVINELLLVHIALAVLSYAFFAIAFVNSLLYIIQYRNLKEKNFDQNYFRIGSVATLETIVFYSTLIAWIILILSTILGAQWGIFAVGKEIFIDPKVIFSTIITLLYGVYILIRIKKWISQRNLIYFNIILFCLCMINLFFLTHFR
>NZ_CP043847.1|WP_001830773.1|166359_167706_+|glutamyl-tRNA-reductase
MHFVAISINHRTADVTLREQVAFRDDALRLAHEDLYETKAILENVILSTCNRTEVYAIVDQVHTGRYYIQRFLARSFGFEVDDIKDMSEVKVGDDAVEHLLRVTSGLDSIVLGETQILGQMRDAFFLAQNTGTTGTIFNHLFKQAITFAKKAHSETDIADNAVSVSYAAVELAKKVFGKLKSKHAVVIGAGEMGELSLLNLLGSGISNVTIVNRTLSKAKILAEKHNVSYDSLSALPSLLETTDIVISSTSAEDYIITNSMVKTISETRKLDSLVLIDIAVPRDIEPGIDAITNIFNYDVDDLKDLVDANLRERQLAAETIAGQIPEEIDSHNEWVNMLGVVPVIRALREKAMNIQAETMESIDRKLPDLSERERKVISKHTKSIINQMLKDPIKQAKELSTDKKSNEKLELFQNIFDIEAEDPREKAKLEKESRAKEILAHRIFSFE
>NZ_CP043847.1|WP_017464984.1|165602_166190_+|YihA-family-ribosome-biogenesis-GTP-binding-protein
MNINPNNINLIISAVKKAQYPDTGLTEVALSGRSNVGKSTFINSMIGRKNMARTSQQPGKTQTLNFYNIDEQLIFVDVPGYGYAKVSKVQREKFGKMIEEYITQRENLKLVIQLVDLRHQPTEDDVLMYNYLKHFDIPTLVICTKEDKIAKGKVQKHIKSIKDKLELEPGDNIISYSSIKNSKQQEIWNFIEAYI
>NZ_CP043847.1|WP_001830765.1|164228_165491_+|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpX
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEGFTELPTPKEIMDHLNEYVIGQEKAKKSLAVAVYNHYKRIQQLGPNEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENILLRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQELIQIDTTNILFILGGAFDGIDEVIKRRLGEKVIGFASNEADKYDEEALLEQIRPEDLQSYGLIPEFIGRVPIVANLETLDVAALKNILTQPKNALVKQYTKMLELDNVELEFSEEALSAISEKAIERKTGARGLRSIIEEALIDIMYDVPSSENVSKVVITEQTINEEIEPELYDDEGNLINKNKTSA
>NZ_CP043847.1|WP_145355167.1|162640_163942_+|trigger-factor
MTATWEKKEGNEGVLTVTVPAEKVNKALDQAFKKVVKQINVPGFRKGKVPRPIFEQRFGVEALYQDAVDILLPEAYGEAIEETEINPVAQPEVNVTQIEKGKDFIFEATVTVEPEVKLGDYKGLEIEKQETDLSDEELQESIDHSLSHLAEMVVKEDGAVENGDTVNIDFSGSVDGEEFDGGQAEGYDLEIGSGSFIPGFEEQIEGMKTGDEKDVVVTFPEEYHAEELAGKEATFKTKVNEIKFKDVPELNDEIANELDSEAESVDEYKENLRKRLSEQKATEAENTEKEEAINKATENASIDIPEAMINTELDRMIQEFGQRIQQQGLDLQTYYQISGQNEEQLRDQMKDDAEQRVKTNLTLTAIADEENIEVSDEDIDKELEKMSEQFNISVEDIKSTLGNTDIVKNDVRIQKVIDLLRDNAKYVEATKED
>NZ_CP043847.1|WP_017464982.1|161557_162481_+|hypothetical-protein
MADIIPFPQSKSKMIKQINDAERNADFENMYQLFNVYEQHFDLNEEIALKKCRMLLQLNAYLELREEAIILLKRGFNCYDELMIYYIKSLNGLGQFNEAVEVINQIIDEVKNHKTRMELFPLKEYAISRLDEDRKALSSSLSDFGSLNTREQTSLILQLIDNGHYNFKESVANILISIDLPKNLVSLMLEYLRFAEYSHTITIRKYGETINVNPNHLSGIEHTTIKDKVIPVVMNRLEDGALHILKEAQHLMNNHSILMYPIDIESLYTIDDWIDAYDVYFKQLIGIDINGCNNDTLQFIKSLDNEL
>NZ_CP043847.1|WP_158171693.1|172853_173921_+|AbrB-family-transcriptional-regulator
MKQNFINNLIILLIAIMLSLLLKMLHVILPFMFGPILAALLCIKVFKLKIRWPFWLSQIGLILLGVQIGSTFTQQVIKDISKNWLTIVFVTILLILLALIIAFFFKKIAQVNLETAILSVIPGALSQMLVMAEENKKANILVVSLTQTSRIIFVVILVPLISYFFQDNHHEMNHPTMKVPALSQTLNIWQIIILFSMVSIIYIGMSKINFPTKQLLAPIIVLIIWNMTTHLTFSLDHWMLATAQLIYMIRIGLQIANLMSDLKGRIAIAIAFQNIMLIVTTFLMIIGIHLITNESINELFLGAAPGGMSQIVLVAMATGADVAMISSYHIFRIFFILFVIAPLIGYFINIRLNNK
>NZ_CP043847.1|WP_002474761.1|174087_174648_-|DNA-3-methyladenine-glycosylase-I
MNECAFNTTDPIYIEYHNYYWGQPIYDSKELFKLMALESQHAGLSWLTILKKKESYEQAFYNFEPQFIAHMTEKDIDYLMKFPNIIHNRKKLEAIVSQAKGYLKIEKDYGSFSNFLWSYVNHQPINMGYKKPRDRKKVDQRATQLSKDLKAYGFKFLGPVTVFSFLEAAGLYDSHLEGCPFKPNHE
>NZ_CP043847.1|WP_158171694.1|174990_177621_+|valine--tRNA-ligase
MEMKPKYDPREVEKGRYEEWVSNGYFKPSEDKSKEAYTIVIPPPNVTGKLHLGHAWDTTLQDIITRMKRMQGYDTLYLPGMDHAGIATQAKVEAKLNEQGISRHDLGREKFLQQAWDWKEEYATFIRQQWAKLGLGLDYSRERFTLDDGLSKAVRKVFVDLYNKGIIYRGERIINWDPKARTALSDIEVIHEDVQGAFYHFKYPYADGNGYIEIATTRPETMLGDTAIVVNPNDERYKDVIGKTVILPIVGRELPILADEYVDIEFGSGAMKVTPAHDPNDFEIGQRHQLENIIVMDEYGKMNEKADKYKGMDRFDCRNQLVKDLKEQDLVIKIEEHTHSVGHSERSGAIVEPYLSTQWFVKMKPLAQRALDNQNTKDRIDFFPGRFENTFNRWMEEIRDWTISRQLWWGHQIPAWYHKDTGEVFVGEEAPEDIENWIQDEDVLDTWFSSALWPFSTLGWPDTNADDFKRYYPTNALVTGYDIIFFWVARMIFQGLEFTDRRPFNDVLLHGLVRAEDGRKMSKSLGNGVDPMDVIDEYGADSLRYFLATGSSPGHDLRYSTEKVESVWNFINKIWNAARFSLMNIGEDFKVEDIDLSGNLSLADQWILTRLNETISTVTELSDKYEFGEVGRALYNFIWDEFCDWYIEMSKIPMNGEDESQKQTTRSVLSYVLGKIMKMLHPFMPFVTETIWQSLPHHGETIVKANWPTVDQALIFNESKQTMEQLVEIIKSVRQSRVEVNTPLSKAIPILIQTKDEKIKQTLMDNISYLHKFCNPSQLTIDTEIEIPEKAMTSVVVAGKVVLPLEGLIDMDKEIARLEKELDKLQSELDRVDKKLSNENFVNKAPEKIINEEKEKQQHYQEKYNGVKSRIEQLKA
>NZ_CP043847.1|WP_002440172.1|177631_178897_+|bifunctional-folylpolyglutamate-synthase/dihydrofolate-synthase
MNYLDSLYWIHERSKFGIKPGVKRMEWMLEQLNNPQHKIRGIHVGGTNGKGSTVAYLRTALIENDYSVGTFTSPFIESFNERISLNGVPIMNDEIVQLVERVKPVSEALEIETDLGGATEFEIITTMMFLYFGEINPVDFVIIEAGLGIKNDSTNVFKPVLSILTSIGLDHTDILGTTYLDIAKDKAAIIKPHIPIVYAVKNDDALKYVRDYALEQNAKPIELDREITVVSQDDEFTYRYKDYELETIILNMLGEHQKENAALAITALIELNERQIIELDFNKMIDGIESVNWTGRIEQVKEQPLMVIDGAHNNESIDALVDTIRHYYGRDKIDILFSAIKGKPIHSMINKLNDIASKFYIADFEFPKALAKEEIAEELKLDNLHLIDDYVDFIENYEGDGLIITGSLYFISEVKAKINFN
>NZ_CP043847.1|WP_017464988.1|179080_179791_+|prepilin-peptidase
MLLLAYTCSIIFSFLYQFCNQNILKLQYLYSRSHCDFCHTIIKPLDLLPIISFLKLRGQSRCCNQPLQRLYLIGELVSFGAIFLYYPTHFNIHFTLFLITFLFLLTMCLYDIHSMHIDIRLLFVYTVVSVFTTQTYFGNFIMIFLISHVIYLFASKFIGYGDILLFNILGLIFPLNFFFFIVVFTFIIGGIFAIIFKIFSFKDIKYLPLIPFIFISFVVTSSVYHQLLFLLGGEFY
>NZ_CP043847.1|WP_002474752.1|179787_180468_+|JAB-domain-containing-protein
MRINEMALHEKPRERLITYGAKSLSNVELLAILLNTGRKGFSSIDIANELLKQQSTIRDLKKLSINDLLKIKGIGLYKAVILQAAFELGERINSTSTLDKVQITHPSDVASLMMSTMKDLEQEHFVVLLLNSKNIVTKQAWVYKGTLNSSIIHPREVFNIAIRESSNSIIVVHNHPSGDVTPSKEDITTTYRLKECGDILGINLLDHIIIGDNKFTSLVEAGYFDK
>NZ_CP043847.1|WP_002446629.1|180531_180711_-|hypothetical-protein
MSILTIILIVLLVILLFKVGLSILRFLISAGIVLLCIYLGYQGVLWLFEHFQNFSGFIQ
>NZ_CP043847.1|WP_001832708.1|180875_181361_+|DUF4930-family-protein
MRYIFSVIKNIIAVLAIILIIYIALQHAPFLKNQEWNPLNDMNNHHQNITQKVSQKNNTLYSQPSNDKSYILKENDIINNVPAGQIKTVFNMIDKAEFMSVSGLERMGFNDEYLAGQQGDEFIIYKFGDDYIRVYNTEFEMNEDLNQLKQPINLKPIEAYQ
>NZ_CP043847.1|WP_001830756.1|181444_181585_+|hypothetical-protein
MAEQSKEKQANEQAKAQNLFARWRKEETLYSEDEKKDKSSKKKDKE
>NZ_CP043847.1|WP_074838394.1|181981_182830_+|rod-shape-determining-protein-MreC
MFWVLKFFRNNKLIVVLCAMIIFIALIGLSIRSQTQSPPEQYVGDSVSFGQRVISYPIQFVTGSIGDLFEKGSSKKDKNKIKQLEAKNEELESENKKYKKELDIKDLSKYEPISTSVIARNPDQWMNTILIDKGSKAGIKNNMAVMTTEGLVGRVTKVNQFSSQVDLISTHTRAGKLSVNIHHGTKNIFGLIDRYDNKNEELIISDINNKDSVKKGDKVVTSGLADQLPSGLYIGEVTKVENDQYGLAKQVRVKTGADMTDLTHVYVAKRDVSTIPDEGSDN

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Crispr_ID: NZ_CP043847_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP043847_2

204029-204109

Orphan

Consensus_repeat	Method
CAGAGCAAGTTGGGACTAGGGCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP043847_2

>merge|NZ_CP043847|2|204029-204109|CRISPRCasFinder
CAGAGCAAGTTGGGACTAGGGCCCCAACAAAGAGAATTTCACAAAGAAATTCAACAGGCAGAGCAAGTTGGGACTAGGGCC

>NZ_CP043847|2|2|204029-204109|CRISPRCasFinder
CAGAGCAAGTTGGGACTAGGGCC	CCAACAAAGAGAATTTCACAAAGAAATTCAACAGG
CAGAGCAAGTTGGGACTAGGGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP043847.1\|WP_002468514.1\|199698_200574_+\|cell-wall-amidase	unknown	unknown	gnl\|CDD\|119407
NZ_CP043847.1\|WP_002473628.1\|204602_205379_+\|tRNA-threonylcarbamoyladenosine-dehydratase	unknown	unknown	gnl\|CDD\|224100
NZ_CP043847.1\|WP_017464992.1\|190752_193044_+\|protein-translocase-subunit-SecDF	unknown	unknown	gnl\|CDD\|237276
NZ_CP043847.1\|WP_002476874.1\|212212_214645_+\|ATP-dependent-RecD-like-DNA-helicase	unknown	unknown	gnl\|CDD\|273632
NZ_CP043847.1\|WP_080033030.1\|205571_206852_-\|replication-associated-recombination-protein-A	unknown	unknown	gnl\|CDD\|237355
NZ_CP043847.1\|WP_002473650.1\|214973_217604_+\|alanine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234701
NZ_CP043847.1\|WP_002476878.1\|202222_203989_+\|aspartate--tRNA-ligase	unknown	unknown	gnl\|CDD\|234775
NZ_CP043847.1\|WP_001830800.1\|190142_190403_+\|preprotein-translocase-subunit-YajC	unknown	unknown	gnl\|CDD\|376903
NZ_CP043847.1\|WP_017464637.1\|207879_208875_-\|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274646
NZ_CP043847.1\|WP_017464636.1\|193714_195988_+\|single-stranded-DNA-specific-exonuclease-RecJ	unknown	unknown	gnl\|CDD\|273193
NZ_CP043847.1\|WP_002494288.1\|210261_211380_+\|tRNA-2-thiouridine(34)-synthase-MnmA	unknown	unknown	gnl\|CDD\|234664
NZ_CP043847.1\|WP_080033066.1\|196594_196678_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043847.1\|WP_002473564.1\|207536_207680_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043847.1\|WP_001830806.1\|206928_207351_+\|Rrf2-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224870
NZ_CP043847.1\|WP_158171695.1\|197046_199236_+\|RelA/SpoT-family-protein	unknown	unknown	gnl\|CDD\|223394
NZ_CP043847.1\|WP_002494287.1\|209119_210262_+\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|224029
NZ_CP043847.1\|WP_002476881.1\|196006_196525_+\|adenine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|235028
NZ_CP043847.1\|WP_002474063.1\|200945_202220_+\|histidine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234586
NZ_CP043847.1\|WP_001830766.1\|199249_199702_+\|D-tyrosyl-tRNA(Tyr)-deacylase	unknown	unknown	gnl\|CDD\|235383
NZ_CP043847.1\|WP_001832695.1\|211542_212211_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276809

Protein	Function_ID	Function_description	E-value
NZ_CP043847.1\|WP_002468514.1\|199698_200574_+\|cell-wall-amidase	gnl\|CDD\|119407	cd02696, MurNAc-LAA, N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino acids in certain cell wall glycopeptides. These proteins are Zn-dependent peptidases with highly conserved residues involved in cation co-ordination. MurNAc-LAA in this family is one of several peptidoglycan hydrolases (PGHs) found in bacterial and bacteriophage or prophage genomes that are involved in the degradation of the peptidoglycan. In Escherichia coli, there are five MurNAc-LAAs present: AmiA, AmiB, AmiC and AmiD that are periplasmic, and AmpD that is cytoplasmic. Three of these (AmiA, AmiB and AmiC) belong to this family, the other two (AmiD and AmpD) do not. E. coli AmiA, AmiB and AmiC play an important role in cleaving the septum to release daughter cells after cell division. In general, bacterial MurNAc-LAAs are members of the bacterial autolytic system and carry a signal peptide in their N-termini that allows their transport across the cytoplasmic membrane. However, the bacteriophage MurNAc-LAAs are endolysins since these phage-encoded enzymes break down bacterial peptidoglycan at the terminal stage of the phage reproduction cycle. As opposed to autolysins, almost all endolysins have no signal peptides and their translocation through the cytoplasmic membrane is thought to proceed with the help of phage-encoded holin proteins. The amidase catalytic module is fused to another functional module (cell wall binding module or CWBM) either at the N- or C-terminus, which is responsible for high affinity binding of the protein to the cell wall.	3.34913e-65
NZ_CP043847.1\|WP_002473628.1\|204602_205379_+\|tRNA-threonylcarbamoyladenosine-dehydratase	gnl\|CDD\|224100	COG1179, COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism].	1.14089e-123
NZ_CP043847.1\|WP_002476874.1\|212212_214645_+\|ATP-dependent-RecD-like-DNA-helicase	gnl\|CDD\|273632	TIGR01448, recD_rel, helicase, putative, RecD/TraA family. This model describes a family similar to RecD, the exodeoxyribonuclease V alpha chain of TIGR01447. Members of this family, however, are not found in a context of RecB and RecC and are longer by about 200 amino acids at the amino end. Chlamydia muridarum has both a member of this family and a RecD. [Unknown function, Enzymes of unknown specificity].	0
NZ_CP043847.1\|WP_080033030.1\|205571_206852_-\|replication-associated-recombination-protein-A	gnl\|CDD\|237355	PRK13342, PRK13342, recombination factor protein RarA; Reviewed.	0
NZ_CP043847.1\|WP_002473650.1\|214973_217604_+\|alanine--tRNA-ligase	gnl\|CDD\|234701	PRK00252, alaS, alanyl-tRNA synthetase; Reviewed.	0
NZ_CP043847.1\|WP_002476878.1\|202222_203989_+\|aspartate--tRNA-ligase	gnl\|CDD\|234775	PRK00476, aspS, aspartyl-tRNA synthetase; Validated.	0
NZ_CP043847.1\|WP_017464992.1\|190752_193044_+\|protein-translocase-subunit-SecDF	gnl\|CDD\|237276	PRK13024, PRK13024, bifunctional preprotein translocase subunit SecD/SecF; Reviewed.	0
NZ_CP043847.1\|WP_017464637.1\|207879_208875_-\|LLM-class-flavin-dependent-oxidoreductase	gnl\|CDD\|274646	TIGR03558, oxido_grp_1, luciferase family oxidoreductase, group 1. The Pfam domain family pfam00296 is named for luciferase-like monooxygenases, but the family also contains several coenzyme F420-dependent enzymes. This protein family represents a well-resolved clade within family pfam00296 and shows no restriction to coenzyme F420-positive species, unlike some other clades within pfam00296. [Unknown function, Enzymes of unknown specificity].	1.31123e-176
NZ_CP043847.1\|WP_017464636.1\|193714_195988_+\|single-stranded-DNA-specific-exonuclease-RecJ	gnl\|CDD\|273193	TIGR00644, recJ, single-stranded-DNA-specific exonuclease RecJ. All proteins in this family are 5'-3' single-strand DNA exonucleases. These proteins are used in some aspects of mismatch repair, recombination, and recombinational repair. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP043847.1\|WP_002494288.1\|210261_211380_+\|tRNA-2-thiouridine(34)-synthase-MnmA	gnl\|CDD\|234664	PRK00143, mnmA, tRNA-specific 2-thiouridylase MnmA; Reviewed.	0
NZ_CP043847.1\|WP_001830800.1\|190142_190403_+\|preprotein-translocase-subunit-YajC	gnl\|CDD\|376903	pfam02699, YajC, Preprotein translocase subunit. See.	5.17879e-27
NZ_CP043847.1\|WP_001830806.1\|206928_207351_+\|Rrf2-family-transcriptional-regulator	gnl\|CDD\|224870	COG1959, COG1959, Predicted transcriptional regulator [Transcription].	2.00179e-44
NZ_CP043847.1\|WP_158171695.1\|197046_199236_+\|RelA/SpoT-family-protein	gnl\|CDD\|223394	COG0317, SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription].	0
NZ_CP043847.1\|WP_002494287.1\|209119_210262_+\|cysteine-desulfurase	gnl\|CDD\|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	0
NZ_CP043847.1\|WP_002476881.1\|196006_196525_+\|adenine-phosphoribosyltransferase	gnl\|CDD\|235028	PRK02304, PRK02304, adenine phosphoribosyltransferase; Provisional.	2.02322e-95
NZ_CP043847.1\|WP_002474063.1\|200945_202220_+\|histidine--tRNA-ligase	gnl\|CDD\|234586	PRK00037, hisS, histidyl-tRNA synthetase; Reviewed.	0
NZ_CP043847.1\|WP_001830766.1\|199249_199702_+\|D-tyrosyl-tRNA(Tyr)-deacylase	gnl\|CDD\|235383	PRK05273, PRK05273, D-tyrosyl-tRNA(Tyr) deacylase; Provisional.	2.03435e-80
NZ_CP043847.1\|WP_001832695.1\|211542_212211_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	3.68475e-14

>NZ_CP043847.1|WP_002476878.1|202222_203989_+|aspartate--tRNA-ligase
MNKRTTYCGLVTEEFLNEKVTLKGWVHNRRDLGGLIFVDLRDREGIVQIVFNPDFSEEALQVAETVRSEYVVEVQGVVTKRDAETINPKIKTGQVEVQVSNIEIINKSETPPFSINEENVNVDENIRLKYRYLDLRRQELAQTFKMRHQTTRSIRQYLDNNGFFDIETPVLTKSTPEGARDYLVPSRVHEGEFYALPQSPQLFKQLLMISGFDKYYQIVKCFRDEDLRADRQPEFTQVDIEMSFVDQEDIIAMGEDMLRKVVKDVKGIDVSGPFPRMTYAEAMDRFGSDKPDTRFGMELINVSQLGKEMNFKVFKDTVDNNGEIKAIVAKDAADKYTRKDMDALTEFVNIYGAKGLAWVKVVDDGLSGPIARFFEDANVETLKQLTEAKPGDLVMFVADKPNVVAQSLGALRIKLAKELGLIDESKLNFLWVTDWPLLEYDEDAKRYVAAHHPFTSPKREDIEKLDTEPENVQANAYDIVLNGYELGGGSIRIHDGELQQKMFEVLGFTNEQAQEQFGFLLDAFKYGAPPHGGIALGLDRLVMLLTNRTNLRDTIAFPKTASATCLLTDAPGEVSDKQLQELSLRIRH
>NZ_CP043847.1|WP_002474063.1|200945_202220_+|histidine--tRNA-ligase
MIKMPRGTQDILPQDSAKWRYIENRLHTLMELYNYKEIRTPIFESTELFARGVGDSTDVVQKEMYTFKDKGDRSLTLRPEGTAAVVRSYIEHKMQGEPNQPIKLYYNGPMFRYERKQKGRYRQFNQFGVEAIGAENPSIDAEILAMVMHIYESFGLKHLKLVINSIGDSESRKEYNEALVKHFEPVIDTFCSDCQSRLHTNPMRILDCKIDRDKEAVKNAPRITDYLNDDSKSYYEQVKLHLDNLNISYVEDPNLVRGLDYYTHTAFELMIDNPEYDGAITTLCGGGRYNGLLQLLDGPDETGIGFALSIERLLMALDEEGISLDVSEDFDLFVVTMGEDADRYAVKLINDLRRNGIKVDKDYLNRKIKGQMKQADRLNAKYTVVIGDQELENNEIGVKNMISGESENVQLDELVNYFKSRKEV
>NZ_CP043847.1|WP_002468514.1|199698_200574_+|cell-wall-amidase
MKKIDSWLTKHGLKNRLTLVVIVIFIIFLILLFMFVNLSDEDTGQITITENAELRTGPNAAYPVIYKIEKGESFKKIDRKGKWIEVQNHAGTEKGWVAGWHTNLNIPADQSLSSNPLKGKTIVLDPGHGGSDQGASSSTPSKSLEKNYTLKTAKELKKLLNKEGAHVKMTRSNDKYVSLDDRNIKGDAFISIHNDALDSSNANGVTVYWFKDKQESLAQTLNSAIQKKALLTNRGSRQQNYQVLRQTDIPAVLLELGYISNPTDESMINDQLHRQVVEQAIVDGLKQYFSS
>NZ_CP043847.1|WP_001830766.1|199249_199702_+|D-tyrosyl-tRNA(Tyr)-deacylase
MKIIVQRVKNARVTNDTIDNQINKGYCLLVGVGQNSTEEDVKVIARKIAHARLFEDENDKLNLNIQQVEGEILSVSQFTIYADVKKGNRPGFSNSKAPEQAKDLYQKFNKELEGYGLIVKTGEFGTHMNVEINNDGPVTLIYESQDGKII
>NZ_CP043847.1|WP_158171695.1|197046_199236_+|RelA/SpoT-family-protein
MNNEYPYSADEVLYKAKSYLSTSEYEYVLKSYHIAYEAHKGQFRKNGLPYIMHPIQVAGILTEMRLDGPTIVAGFLHDVIEDTSYTFEDVKDMFIEEIARIVDGVTKLKKVKYRSKEEQQAENHRKLFIAIAKDVRVILVKLADRLHNMRTLKAMPREKQVRISKETLEIYAPLAHRLGINTIKWELEDTALRYIDSVQYFRIVNLMKKKRSEREAYITNAINKIKNEMTKMNLSGEINGRPKHIYSIYRKMIKQKKQFDQIFDLLAIRIIVNSINDCYATLGLVHTLWKPMPGRFKDYIAMPKQNMYQSLHTTVVGPNGDPLEIQIRTHEMHEIAEHGVAAHWAYKEGKTVNQKTQDFQNKLNWLKELAETDHTSADAQEFMESLKYDLQSDKVYAFTPASDVIELPYGAVPIDFAYAIHSEVGNKMIGAKVNGKIVPIDYVLQTGDIIEIRTSKHSYGPSRDWLKIVKSSSAKSKIKSFFKKQDRSSNIEKGKFMVEAEIKEQGFRVEDILTEKNLEVVNEKYHFANDEDLYAAVGFGGVTSIQIVNKLTERQRILDKQKALNEAQEVTKSVPIKKDITTDSGVYVEGLENVLIKLSKCCNPIPGDDIVGYITKGHGIKVHRTDCPNIKNETDRLISVEWVKSKDSTQQYQVDLEVTAYDRNGLLNEVLQAVNSTAGSLIKVSGRSDIDKNAVINISVMVKNVNDVYRVVEKIKQLGDVYTVSRVWN
>NZ_CP043847.1|WP_080033066.1|196594_196678_-|hypothetical-protein
MKYLANIHSNYKVNYNNIDNHFITLRH
>NZ_CP043847.1|WP_002476881.1|196006_196525_+|adenine-phosphoribosyltransferase
MDLKQYVSEVKDWPSAGVSFKDITTIMDNGEAYGYATDQIVEYAKEKNIDIVVGPEARGFIIGCPVAYSMGIGFAPVRKEGKLPREVIRYEYNLEYGTNVLTMHKDAIKPGQRVLITDDLLATGGTIEAAIKLVEQLGGIVVGIAFIIELKYLNGIEKIKDYDVMSLISYDE
>NZ_CP043847.1|WP_017464636.1|193714_195988_+|single-stranded-DNA-specific-exonuclease-RecJ
MIKSKYNWDITQPNTFISESSSDQFKLSSIVKKVLESKNIVDNQEIQNLFEDTNISHDYMLLSDMQKAIDRIKLAIDQNERILVYGDYDADGVTSTTILVSTLRLLGAQVGWYIPNRFTEGYGPNELAFKNAYDEGISLIITVDNGIQGHHEINTIQELGVDVIVTDHHEIGETLPDAFAIVHPMHPNFEYPFKYLCGAGVAYKLAQGLIEHPPQHFIALAAIGTIADLVSLTDENRYIVKQGLKILNSHTPSSIKAILNQAGFNDEITEETIGFIIGPRLNAVGRLEDASLAAELLLSDEFEEAEFLAEQVEHFNHERKDIVSKITDEALLLAEEQIKQGHLFLLLAKEGWHEGVLGIVASKIVETYALPTLILNIDENQNHAKGSARSIEQVSMFDILNDHQHLIDKFGGHHMAAGMTMSIDNIERLHKELDMWMKELTVTTSLEPSIKVDAQLEEKEINIKNIKDIFQLRPFGTDFNSPLFMVRDLIVKSTKGIGQDNKHLKLTLGHSGLTALFWNHGHLASELEPGQPIHIIGTLQINEWNGNQTPQFIIKDIAIDQLQILDYRSKRKNIQFKESESNVAYVIHPKLKKSNSHYYHYGEAIDRPYDKIVFRDLPNTMVEIEQTLEHSQISQLYLVLQHEKSIYFEGIPSKSLFKKCYKALINKKETDLIKEGMLLCEYLNIKPEILTFMLKVFKELEFIYDEKGLIKINPAPNKQDIENSRIYQMRQARMEVEERLLYDDFLNIKEWIISKLT
>NZ_CP043847.1|WP_017464992.1|190752_193044_+|protein-translocase-subunit-SecDF
MKKTSRIIAFILLVALLFTGMGMTYKNVVKNVNLGLDLQGGFEVLFQVDPLNKGDKIDKKALQATSQTLENRVNVLGVSEPKIQIEDPNRIRVQLAGIKDQAEARKLLSTQANLTIRDAEDHVLMSGSDIKQGSAKQEFKQETNQPTVTFKVKSKDKFKKVTEKISKKRDNVMVVWLDFEKGDSYKKEAKKQQEGKKPKFISAASVDQPINSSSVEISGGFNGKKGVEEAKQIAELLNAGSLPVDLKEIYSNSVGAQFGQDALDKTIFASIVGIALIYLFMLGFYRLPALVAIIALTAYIYLTLVAFNFISGVLTLPGLAALVLGVGMAVDANIIMYERIKDELRIGRTLKQAYSKANKSSFLTIFDSNLTTVIAAAVLFFFGESSVKGFATMLLLGILMIFVTAVFLSRGLLSLLISSNFFKKQYWLFGVKKKDRHDINEGKDVHDLKTSYERLNFVKLAKPLISLSILIVIIGLIIISIFKLNLGIDFSSGTRADIQSKNAITQAQVEKTVKSAGLEADQIQINGSGNKNATVQFKKDLSREEDNKLSAKVKSEFGDNPQINTVSPLIGQELAKNAVTALILASIGIIIYVSLRFEWRMGLSSVLALLHDVFIIIAIFSLFRIEVDLTFIAAVLTIVGYSINDTIVTFDRVRENLHKVKVITHTDQIDDIVNRSIRQTMTRSINTVLTVVVVVVAILILGAPTIFNFSLALLIGLLSGVFSSIFIAVPLWGMFKKRQFKKTKNNKLVVHKEKKSNDEKILV
>NZ_CP043847.1|WP_001830800.1|190142_190403_+|preprotein-translocase-subunit-YajC
MELTSLIIPILLLVVMYFLLIRPQQKRAKEHRAMINRVEAGQKITTIGGIKGTIKAVDETSVIITVNSNGTEMTFEKPAIKQVDPS
>NZ_CP043847.1|WP_002473628.1|204602_205379_+|tRNA-threonylcarbamoyladenosine-dehydratase
MKHQFSRNELAIGQEGLELLKNKTVAVLGVGGVGSFAAEALARTNIGHIILIDKDDVDITNVNRQIHALTSTIGQSKVTLMEERIKLINPDCKVTSLHMFYTEETYKDIFNNYDIDYFIDASDTIIYKVHLMKECLERGIELISSMGAANKTDPTRFEIADISKTHTDPMAKVIRNRLKRLGIRKGVKVVFSDESPIVIREDVKETVGDKNAINRKGQMPPSSNAFVPSVVGLICASYVVNDILKDIPVRRIKDKGQN
>NZ_CP043847.1|WP_080033030.1|205571_206852_-|replication-associated-recombination-protein-A
MKNVSTEPLASRMRPKNIDEIISQQHLVGPKGIIRRMVDTKRLSSMIFYGPPGIGKTSIAKAISGSTQFKFRQLNAVTNTKKDMQLVVEEAKMSGQVILLLDEIHRLDKAKQDFLLPHLENGKIVLIGATTSNPYHAINPAIRSRAQIFELYPLDQDDIRLALDRAINDKERGLSTYHPIVDEDAIEYFSTQSQGDVRSALNALELAVLSAHIDEENKRHITLDDAKDCLQKGAFVSDKDGDMHYDVMSAFQKSIRGSDVNAALHYLARLIEAGDLPTIVRRLLVISYEDVGLASPNAGQRTLAAIQSAERLGFPEARIPLSQAVIELCLSPKSNSGITAIDKALGDIRNGHIGQIPDYLKDGHYSGAKKLGRAIGYKYPHNYENGHVVQQYLPEKLKNRVYYEPKTTSKSEQQFKTIYDNLRNKT
>NZ_CP043847.1|WP_001830806.1|206928_207351_+|Rrf2-family-transcriptional-regulator
MKISTKGRYGLTLMISLAKREGQGCVSLKTIAEENKLSDLYLEQLVGPLRNAGLIRSVRGAKGGYQLRVPSEEITAGDIIRLLEGPITFVESIDSEPPAQKQLWIRMRDAVRDVLDHTTLKYLADYKDTNEDLEGYMFYI
>NZ_CP043847.1|WP_002473564.1|207536_207680_+|hypothetical-protein
MGFMDKAKEAAEKFKDSDNEQVKKVKDKVNEYTGGEDNKDKKDKEDK
>NZ_CP043847.1|WP_017464637.1|207879_208875_-|LLM-class-flavin-dependent-oxidoreductase
MKNIKLSALNLVPIREGQEDKDAINDMVILAQALDDLDYERYWIAEHHNAPNLVSSATSLLIQHTLEHTHSIKVGSGGIMLPNHAPLVVAEQFGTLETLFPQRVDLGLGRAPGTDMMTASALRRDQHNGVYQFPEEVEQLQQYFGPSHQQAYVRAYPAVDKNVPMYILGSSTDSAHLAARKGLPYVFAGHFAPQQMKEALQIYRELFEPSEVLDKPYVIVCLNTIVADSDEQAEYLATTMAQIMVSITRGKMQPVQPPTDDLKALLTPREYELAQQRLKGSLIGSEDTVKQKLQSFITEYGDIDELMAISYIYDQDKQIESYRRLKRAIKS
>NZ_CP043847.1|WP_002494287.1|209119_210262_+|cysteine-desulfurase
MEVYADYAATTPVKQEVIDAMMEIYQSHFGNPSSIHSIGRDARKYLDQSRRTVAQLLGANPNEVIFTSGATESNNTAIKGLVKANEQLGNHIITTKIEHHSVLHVYEQLEKEGYDVTYLDVDDTGAVDLDQLKETINDRTILVSIMFVNNEIGTVQNIYDIEDIIADTHALFHVDAVQAIGHLDLDFHNFKIDTMSISAHKFGGPKGVGLLLVKEHTPIAYNQLGGEQETKRRAGTENLPQIVGLTKALELAITNQDVNNIHLMNLKELFLVQLQERAIPFELNGSMTDSTGHILNIYFPFIDVETMLTLLDLAHVYVSSGSACTAGSTTPSHVLAAMFEDEERAKHSVRFSFNEQTTTQEIKYIVAEIHKIYHKFKEES
>NZ_CP043847.1|WP_002494288.1|210261_211380_+|tRNA-2-thiouridine(34)-synthase-MnmA
MSNKDIRVVVGMSGGVDSSVTAYLLKEQGYDVIGIFMKNWDDTDENGVCTATEDYNDVIAVCNQIGIPYYAVNFEEQYWDKVFTYFLDEYKKGRTPNPDVMCNKEIKFKAFLEHALKLGADYVATGHYARIRRHDDGHVEMLRGVDNNKDQTYFLNQLSQEQLSKVMFPIGDIEKSEVRRIAEEQNLATAKKKDSTGICFIGERNFKEFLSQYLPAQSGEMLTLNGKKMGQHSGLMYYTIGQRHGLGIGGDGDPWFVVGKNLNDNVLYVEQGFHHDALYSDYLIASDYSFVNPSEIDLEKGFECTAKFRYRQKDTKVYVQRENENSIRVTFAEPVRAITPGQAVVFYNQEVCLGGATIDDVYKNEGQLSYVV
>NZ_CP043847.1|WP_001832695.1|211542_212211_+|tetratricopeptide-repeat-protein
MHEQSKIYQNIKDGKLDTALKDLFENIEENPAIVENYINAGIVLSDVGEIEKAERFFQKALTIEPENGAVYYNLANIYYNEERYNEAIKLYQTALQYEVAKKDCNYMIGMSFNQLGAFKEALPFLMTAAEMDDDRDLEVQFQYGLVLCQLEMFDEAIKQLNKVLSIDSQHVDGIYNLGLATYMKNENLDEAIAYFEQAISIDEKHLLSQHALKTFKTMKEEE
>NZ_CP043847.1|WP_002476874.1|212212_214645_+|ATP-dependent-RecD-like-DNA-helicase
MSDPTLFDYSMIKGTVDAILFQNTDNFYTVLKVDTIESNEKFDSMPTVVGFLPNVVEGDVYTFKGQVVQHPRYGKQLKAETFEKELPQTKEAIISYLSSDLFKGIGKKTAQNIVNTLGENAINDILTRPEILERVPSLPKKKQKQIADQINANQESEKIMIRLHDLGFGPKLSMAIYQFYMGDTLNVLDKNPYQLVYDIKGIGFNKADQLARNVGIEPHSPERLKAALLFTLEEECIKQGHTYLPRTIVIETTQNLLNEDIEKPVETEQLLEIIDVLSEEKKLISEADQVSIPSLYYSELKSVQNLYRIKTNTSKLKEIEQSDLQIHIGDIESQNEVNYSASQKEALETAINSKIMLLTGGPGTGKTTVIKGIVELYAEIHGLSLDYDDYNEDDYPVVLAAPTGRASKRLHESTGLEAMTIHRLIGWNQDTQPQDILENEINARLIIIDEMSMVDTWLFHQFLSAVPLEAQIVFVGDEDQLPSVGPGQVFKDLIDSEIIPRVNLTEVYRQQDGSSIIDLAHRMKLNEPIDITKRYHDRSFIRCGTNQIPDVVDKVVKSAVAKGYDMSDIQVLAPMYKGNAGIKRLNQVLQSILNPKQQDDREIEFGEAVFRKGDKVLQLVNRPNDNIFNGDIGIIVGIFWAKENALNKDVLVVDFEGNEITFTKQDLMELTHAYCTSIHKSQGSEFPIVIMPIVRQYYRMLQRPILYTGLTRAKQSLVLLGEQEAFDIGLKTNGQIRLTQLNDLLKSYFGQNKDNLTTNKQTINEQKENNNHLDLNNEKENDIQLNESTIFQIDPMINMGEMTPYDFVER
>NZ_CP043847.1|WP_002473650.1|214973_217604_+|alanine--tRNA-ligase
MKKMKASEIRQKYLDFFVEKGHMIEPSAPLVPIDDDSLLWINSGVATLKKYFDGRETPKKPRIVNSQKAIRTNDIENVGFTARHHTFFEMLGNFSIGDYFKHEAIEFAWEFLTSDKWMGMEPEKLYVTIHPEDTEAFRIWHEDIGLEESRIIRIEGNFWDIGEGPSGPNTEIFYDRGSAYGKDDPAEEMYPGGENERYLEVWNLVFSEFNHNKDNTYTPLPNKNIDTGMGLERMTSISQNVRTNYETDLFMPIIKEVEHVSGKKYLIDDAQDVAFKVIADHIRTISFAIADGALPANEGRGYVLRRLLRRAVRFSQSLGINEPFMYKLVDIVADIMEPYYPNVKDKSNFIKRVIKSEEERFHETLEEGLTILNELIKEAKNSDQVIKGHDAFKLYDTYGFPIELTEELATQENLSVDMPTFEQEMQQQRDRARQARQNSQSMQVQSEVLKNIQDDSQFVGYETTDYQSLITHIIYNGEEVKHAEAGETIYFILRETPFYAVSGGQVADKGTVGNESFEINVTDVTKAPNGQNLHKGIVQFGEATQNAKVEARVNKEDRRLIQKNHSATHLLHAALKEVLGDHVNQAGSLVEPERLRFDFSHFGPMTQEEINLVERRVNEEIWRAIDVRIQEMSIEEAKSIGAMALFGEKYGDIVRVVNMAPFSIELCGGIHVNNTAEIGLFKIVSESGTGAGVRRIEALTGKGAFLHLEEIETQFNNIKNHLKVKSDNQVVEKVKQLQEEEKGLLKQLEQRNKEITSLKMGNIEEQVELINNLKVLATEVEIPNPKAIRSTMDDFKSKLQDTIIVLVGQVDGKVSVIATVPKSLTNQVKAGDLIKNMTPIIGGKGGGRPDMAQGGGTQPEKITEALRFIKDYIKNL

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Crispr_ID: NZ_CP043847_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP043847_3

1127646-1127737

Orphan

Consensus_repeat	Method
GAATTTCTCGGTGAAATTCTCTTTGTTGGGGCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP043847_3

>merge|NZ_CP043847|3|1127646-1127737|CRISPRCasFinder
GAATTTCTCGGTGAAATTCTCTTTGTTGGGGCCGCGAACCCCAACTTGCTCTGTCCGTAGAATTTCTCGGCGAAATTCTCTTTGTTGGGGCC

>NZ_CP043847|3|3|1127646-1127737|CRISPRCasFinder
GAATTTCTCGGTGAAATTCTCTTTGTTGGGGCC	GCGAACCCCAACTTGCTCTGTCCGTA
GAATTTCTCGGCGAAATTCTCTTTGTTGGGGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP043847.1\|WP_002493526.1\|1134891_1135818_-\|GTP-binding-protein	unknown	unknown	gnl\|CDD\|349766
NZ_CP043847.1\|WP_059279896.1\|1131817_1133374_-\|DASS-family-sodium-coupled-anion-symporter	unknown	unknown	gnl\|CDD\|279307
NZ_CP043847.1\|WP_017464496.1\|1136724_1138419_-\|thiol-reductant-ABC-exporter-subunit-CydC	unknown	unknown	gnl\|CDD\|227320
NZ_CP043847.1\|WP_002476398.1\|1125281_1126040_-\|DeoR/GlpR-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224268
NZ_CP043847.1\|WP_011082622.1\|1117959_1118052_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043847.1\|WP_158171790.1\|1126891_1127362_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043847.1\|WP_080395203.1\|1133506_1134454_-\|malate-dehydrogenase	unknown	unknown	gnl\|CDD\|180477
NZ_CP043847.1\|WP_002474370.1\|1120860_1122033_-\|N-acetylglucosamine-6-phosphate-deacetylase	unknown	unknown	gnl\|CDD\|238434
NZ_CP043847.1\|WP_001830355.1\|1118193_1119033_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381297
NZ_CP043847.1\|WP_158171791.1\|1129310_1129934_+\|DUF1361-domain-containing-protein	unknown	unknown	gnl\|CDD\|226780
NZ_CP043847.1\|WP_158171788.1\|1122406_1124359_-\|PTS-transporter-subunit-EIIA	unknown	unknown	gnl\|CDD\|224218
NZ_CP043847.1\|WP_158171789.1\|1126295_1126778_-\|Cys-tRNA(Pro)-deacylase	unknown	unknown	gnl\|CDD\|272853
NZ_CP043847.1\|WP_002474388.1\|1127742_1128906_-\|multidrug-efflux-MFS-transporter-NorA	unknown	unknown	gnl\|CDD\|340883
NZ_CP043847.1\|WP_002476401.1\|1119274_1120624_-\|HlyC/CorC-family-transporter	unknown	unknown	gnl\|CDD\|224173
NZ_CP043847.1\|WP_001830344.1\|1124364_1125285_-\|1-phosphofructokinase	unknown	unknown	gnl\|CDD\|274804
NZ_CP043847.1\|WP_017464499.1\|1130249_1131623_-\|deoxyribodipyrimidine-photo-lyase	unknown	unknown	gnl\|CDD\|223492
NZ_CP043847.1\|WP_064206183.1\|1129930_1130200_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043847.1\|WP_074838947.1\|1126072_1126171_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043847.1\|WP_002438861.1\|1134576_1134879_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043847.1\|WP_001830335.1\|1136038_1136482_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670

Protein	Function_ID	Function_description	E-value
NZ_CP043847.1\|WP_002493526.1\|1134891_1135818_-\|GTP-binding-protein	gnl\|CDD\|349766	cd03112, CobW-like, cobalamin synthesis protein CobW. The function of this protein family is unknown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterize it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage caused by mitomycin. YijA gene is a homologue of the CobW gene which encodes the cobalamin synthesis protein/P47K.	1.53026e-66
NZ_CP043847.1\|WP_002476398.1\|1125281_1126040_-\|DeoR/GlpR-transcriptional-regulator	gnl\|CDD\|224268	COG1349, GlpR, Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism].	1.60974e-79
NZ_CP043847.1\|WP_080395203.1\|1133506_1134454_-\|malate-dehydrogenase	gnl\|CDD\|180477	PRK06223, PRK06223, malate dehydrogenase; Reviewed.	0
NZ_CP043847.1\|WP_002474370.1\|1120860_1122033_-\|N-acetylglucosamine-6-phosphate-deacetylase	gnl\|CDD\|238434	cd00854, NagA, N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to amino-sugar-nucleotides, which is needed for cell wall peptidoglycan and teichoic acid biosynthesis. Deacetylation of N-acetylglucosamine is also important in lipopolysaccharide synthesis and cell wall recycling.	1.83789e-164
NZ_CP043847.1\|WP_059279896.1\|1131817_1133374_-\|DASS-family-sodium-coupled-anion-symporter	gnl\|CDD\|279307	pfam00939, Na_sulph_symp, Sodium:sulfate symporter transmembrane region. There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.	8.23236e-93
NZ_CP043847.1\|WP_158171791.1\|1129310_1129934_+\|DUF1361-domain-containing-protein	gnl\|CDD\|226780	COG4330, COG4330, Predicted membrane protein [Function unknown].	3.23584e-28
NZ_CP043847.1\|WP_158171788.1\|1122406_1124359_-\|PTS-transporter-subunit-EIIA	gnl\|CDD\|224218	COG1299, FruA, Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism].	3.52488e-141
NZ_CP043847.1\|WP_158171789.1\|1126295_1126778_-\|Cys-tRNA(Pro)-deacylase	gnl\|CDD\|272853	TIGR00011, Putative_Cys-tRNAPro/Cys-tRNACys_deacylase_EbsC, Cys-tRNA(Pro) deacylase. This model represents the YbaK family, bacterial proteins whose full length sequence is homologous to an insertion domain in proline--tRNA ligases. The domain deacylates mischarged tRNAs. The YbaK protein of Haemophilus influenzae (HI1434) likewise deacylates Ala-tRNA(Pro), but not the correctly charged Pro-tRNA(Pro). A crystallographic study of HI1434 suggests a nucleotide binding function. Previously, a member of this family was described as EbsC and was thought to be involved in cell wall metabolism. [Protein synthesis, tRNA aminoacylation].	3.48802e-77
NZ_CP043847.1\|WP_002474388.1\|1127742_1128906_-\|multidrug-efflux-MFS-transporter-NorA	gnl\|CDD\|340883	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters. This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.36448e-66
NZ_CP043847.1\|WP_002476401.1\|1119274_1120624_-\|HlyC/CorC-family-transporter	gnl\|CDD\|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	5.07155e-154
NZ_CP043847.1\|WP_001830344.1\|1124364_1125285_-\|1-phosphofructokinase	gnl\|CDD\|274804	TIGR03828, pfkB, 1-phosphofructokinase. This enzyme acts in concert with the fructose-specific phosphotransferase system (PTS) which imports fructose as fructose-1-phosphate. The action of 1-phosphofructokinase results in beta-D-fructose-1,6-bisphosphate and is an entry point into glycolysis (GenProp0688).	3.62711e-132
NZ_CP043847.1\|WP_017464499.1\|1130249_1131623_-\|deoxyribodipyrimidine-photo-lyase	gnl\|CDD\|223492	COG0415, PhrB, Deoxyribodipyrimidine photolyase [DNA replication, recombination, and repair].	4.39919e-141
NZ_CP043847.1\|WP_001830335.1\|1136038_1136482_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.47118e-19
NZ_CP043847.1\|WP_017464496.1\|1136724_1138419_-\|thiol-reductant-ABC-exporter-subunit-CydC	gnl\|CDD\|227320	COG4987, CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones].	1.21551e-172
NZ_CP043847.1\|WP_001830355.1\|1118193_1119033_-\|aldo/keto-reductase	gnl\|CDD\|381297	cd19071, AKR_AKR1-5-like, AKR1/2/3/4/5 family of aldo-keto reductase (AKR) and similar proteins. Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. The family includes AKR1A/B/C/D/E/G/I, AKR2A/B/C/D/E, AKR3A/B/C/D/E/G, AKR4A/B/C, AKR5A/B/C/D/E/F/G/H, and similar proteins.	2.278e-138

>NZ_CP043847.1|WP_158171790.1|1126891_1127362_-|hypothetical-protein
MKLKNLFLSSVAVILSICLVLLLFLATNQNALAKVHKTICTFTKVKTVSHNDIFPNLNMNHVAEASEKNSDHQKNINKTNQQSVRTQTSYDFNPQECNVIALNYAENHLSKKYNIERTFNESLHSVYVFSSENKLHQTKVKVNKSGTVHASNINYH
>NZ_CP043847.1|WP_158171789.1|1126295_1126778_-|Cys-tRNA(Pro)-deacylase
MSKTKKTNAMRILDRAKINYQMNTYEVTDKHQHGEEIAQLVGAKIEEVFKTLVLENSNHEHYVFIIPVNETLDMKKAAHVVNEKKLNLMPLDQLKQVTGYVRGGCSPIGMKHSFKTTIDASAKNLEKVYISGGQRGMQIIIHVNDLIDMTKAQVESITQN
>NZ_CP043847.1|WP_074838947.1|1126072_1126171_+|hypothetical-protein
MATLTYFNQNLPFSIKNNHSVTKIKTPFRLGV
>NZ_CP043847.1|WP_002476398.1|1125281_1126040_-|DeoR/GlpR-transcriptional-regulator
MISEKRQNLILQELTQKDFLTLQDLVDRTGCSASTIRRDLSKLQNMGKLQRVHGGATIHQNRVKEPKLSEKRTQNLREKQEIAKRAACDIQDHECIFLDAGSSTFELIQYIEAKDITVVTNGMTHVEELLKHGIKTLMIGGQVKPTTMATVGANALETLRRYCFDRAFIGMNGIDVKYGLTTPDEQEALIKETAMKLSNHKYVLVDQSKFNQIYFARVPILDGLSIITSQKAMQSKMTEAYMNEFNFIGGKS
>NZ_CP043847.1|WP_001830344.1|1124364_1125285_-|1-phosphofructokinase
MIYTVTFNPSIDYIIFTDGFEISGLNRAKATYKFAGGKGINVSRVLKTLDVDSTALGFSGGFPGDFIAQTLEDSNIQSDFVQVDEDTRINVKLKSGQETEINAPGPKVTHAQFEQLLSQIRRTTNDDIVIVAGSVPNSIPSDAYAQIAQITEKTGAQLVVDAEKDLVETVLPYRPLFIKPNKDELEVMFNTTVKSDEDVIKYGKEILKKGAQSVIISLGGDGAIYVDQHQSIKAVNPQGHVVNTVGSGDSTVAGMVAGLSMGLNVDEAFQQAVASGTATAFSEDLATRDAIENIKSQVTISVLDGE
>NZ_CP043847.1|WP_158171788.1|1122406_1124359_-|PTS-transporter-subunit-EIIA
MRITELLTKETIAMDLDASDKSGVITELVNQLDKAGKLSDPVSFKEAIHNRESQSTTGIGEGIAIPHAKVAAVKTPAIAFGKSKEGVDYQSLDMQPAHLFFMIAAPEGGAQTHLDALAKLSGILMDEKIREKLIHAESPEEVLNIIDEADDEATKEEEAEANENATVSTDNSIQDNNEPYVLAVTACPTGIAHTYMARDALKKQAEKMNIKIKVETNGSSGIKNHLTEQDIERATGIIVAADVHVETDRFDGKNVVEVPVADGIKRPEELINTALDTNRKPFVAQGGSKKHDDNEEKLSPGKAFYKHLMNGVSNMLPLVISGGILMAIVFLFGANSFKPDSSEYNAFAEQLWNIGKNSAFALIIPILAGFIARSIADKPGFAAGLVGGMLAISGGSGFIGGIIAGFLAGYLTQGIKYITRKLPQAIEGLKPTLIYPLLSVSITGLLMVYVFNPPAAWLNHLLLNGLNSLSGSNIMLLGLVIGAMMAIDMGGPFNKAAYVFATAALTEGNAAPITAAMIGGMIPPLAIATAMLIFRRKFTKEQRGSIVPNYVMGLSFITEGAIPFAAADPLRVIPSMMVGSGVAGAIALGLGSSIKAPHGGIFVIVGTDFNHILQTLIALVVGTLVSALIYGFLKPKVTDNEIQASQAMDE
>NZ_CP043847.1|WP_002474370.1|1120860_1122033_-|N-acetylglucosamine-6-phosphate-deacetylase
MSEYVLTNGIVYTENEMINNGYVHIKDGKILDVGKCPFHPSSSHNTIDIIDVKKRHILPGFIDIHIHGGYGEDAMDASEQGLQHLAESLLSEGTTSFLATTMTQSTVNIERALQTIAKYTQQQDVTNAAEIVGVHLEGPFISEHKVGAQHPQFVQRPTVDKIKSFQEVANGLIKIITYAPEVDGATETLKTMKNDIIFSIGHTVATFDQANTAVSHGAKHITHLYNAATGFQHREPGVFGAAWLNQGLHTEMIVDGVHSHPASIALAYRLKGNQSCYLITDAMRAKGMPEGHYDLGGQDVIVKGSEARLSSGALAGSILKMNEGLKNLIQFTGDTIEHLWRVTSLNQAITLGIDDVKGSIKIGKDADIVIIDDACNVETTIKNGKYHAFK
>NZ_CP043847.1|WP_002476401.1|1119274_1120624_-|HlyC/CorC-family-transporter
METSTIISLVIFFLLIALTTVFVGSEFALVKVRSTRIEQLVDEGNKSAKIVKKMIDNLDYYLSACQLGITVTSLGLGWLGEPTFEKMMHPLFELLHLPSPLTTTISFVVSFIVVTYLHVVLGELAPKSFAIQHTEQLALLYSRPLFYFGNFMKPLIWLMNGSSRVIVRMFGFDPDAQTDAMSEEEIKIIINNSYNGGEINQTELAYMQNIFSFDERHAKDIMVPRTQMVTLNEPFNVDELLDTIKEHQFTRYPITEDGDKDHVKGFINVKEFLTEYASGKPIKIANYIHELPMISETTRISDALVRMQREHVHISLIIDEYGGTAGILTMEDILEEIVGEIRDEFDDDEVNDIVKLDDHTYQINGRVLLDDLNEKFGIEFEDSEDIDTIGGWLQSQNTNLQKDDFVDTEYDRWTITEIDNHQIIWVNLNYEFNSGRPSVDEEQEDDERD
>NZ_CP043847.1|WP_001830355.1|1118193_1119033_-|aldo/keto-reductase
MTNDVQILNNGYPMPAVGLGVYKIADEQMEEVVRTALDAGYRAFDTAYFYGNEKALGSALKHSNVERDELFITSKLWNDYQGYDQTIEYFNKSLDNLGLDYLDLFLIHWPCENDQLYIESYKALEHLYEEGKIKAIGVCNFKIHHLEKLMKETKITPQVNQIELHPYFNQQDVQDFCDEHDIKVTAWMPLMRNKGLLDDPVITDIAHRYDKTPAQIVLRWHLAHNRIIIPKSQTPKRIKENFDIFDFNLELTDVAEIDSLNKNARQGKDPDDVSIGDLK
>NZ_CP043847.1|WP_011082622.1|1117959_1118052_-|hypothetical-protein
MYDKEIDKMIANSSEKRMSFNENQSHRPLL
>NZ_CP043847.1|WP_002474388.1|1127742_1128906_-|multidrug-efflux-MFS-transporter-NorA
MKKQLFILYFNIFLIFLGIGLVIPVLPVYLKDLGLKGSDLGMLVAAFALSQMIISPFGGTLADKLGKKLIICIGLVFFAVSEFMFAAGQSFTILIISRVLGGFSAGMVMPGVTGMIADISPGADKAKNFGYMSAIINSGFILGPGFGGFLAEISHRLPFYVAGTLGVVAFIMSVLLIHNPHKATTDGFHQYQPELLTKINWKVFITPVILTLVLAFGLSAFETLFSLYTADKVNYTPKDISIAIIGGGVFGALFQVFFFDKFMKYMSELNFIAWSLLYSAIVLVMLVLANGYWTIMIISFVVFIGFDMIRPALTNYFSNIAGKRQGFAGGLNSTFTSMGNFIGPLVAGALFDVNLEFPLYMAIAVSLSGIIIIFIEKGLKSRRKEAN
>NZ_CP043847.1|WP_158171791.1|1129310_1129934_+|DUF1361-domain-containing-protein
MVMQSRYFARIYFIILFVISMTESHIFNFMTLNLFLAYVPFELCLLLKLFKPVKAFEWPLFIVFGLIFLLLVPNTFYMITDLIHLNQFQFNFLAGLNITEWIYFTYLVLGVLLAIYLTILIFLEIAHFTTYIWLNRLLIVILMFLNGLGIYIGRFLRLHTVYLLNAPLKIVKEFFLIIDVKALLFVILMVLIQATVILFVKGVRLYQ
>NZ_CP043847.1|WP_064206183.1|1129930_1130200_+|hypothetical-protein
MIIEVILMVCLIIIQLIIGHLWHQIGWSYTKAILLMCLPLGIGLYLMQLFYYEPRYTNWEVPFKTKLNLKYMYILTLLEYILIYVCFFM
>NZ_CP043847.1|WP_017464499.1|1130249_1131623_-|deoxyribodipyrimidine-photo-lyase
MAIGVILNRVFRLNNNPLFDYIYRNKESINHCYFIIPTEEFEEEAKKKAQYYYGSIQKFMYELQRYDIEPFLMSYDKLIDFCKKQAIDKVVVAGDIMSYHHEEYDILHQRKRFKQANIQVISLRANHYFNPRKTHNKQGEPYKVFTSFYRKWRPYLMIRDEYDYHLEDITKVAVKSQHKIKEDYHSYGISERDVQNRWSEFLSQDIENYKENREYLPEVLTSQLSIYLAYGMIDIIQVFNDLLQNYDKNEQNYEAFIRELIFREFYYVLMTNYPETAHVAFKEKYQQMKWSYNEENFKLWKDGNTGFPIIDAAMEELKTTGFMHNRMRMVVSQFLTKDLFIDWIWGESFFKQKLIDYDAASNVHGWQWSASTGTDAVPYFRMFNPIRQSERFDNNARYIKTYIPRLNKVNAKYLHDTHKFEQQIKGQGVEIGKDYPKQMIDHKESRQRVMSEFKALD
>NZ_CP043847.1|WP_059279896.1|1131817_1133374_-|DASS-family-sodium-coupled-anion-symporter
MAKGDQYQAHTEKYHDKKSKKSYKPVWIIISFIILITILLLPTPAGLPVMAKAALAILAFAVVMWVTEAVTYPVSATLILGLMILLLGLSPVQDLSEKLGNPKSGDIILKGSDILGTNNALSHAFSGFSTSAVALVAAALFLAVAMQETNLHKRLALLVLSIVGNKTRNIVIGAILVSIVLAFFVPSATARAGAVVPILLGMIAAFNVSKDSRLASLLIITAVQAVSIWNIGIKTAAAQNIVAINFINQNLGHDVSWGEWFLYAAPWSIIMSIALYFIMIKFMPPEHDAIEGGKELIKKELNKLGPVSHREWRLIVISVLLLFFWSTEKVLHPIDSASITLVALGIMLMPKIGVITWKGVEKKIPWGTIIVFGVGISLGNVLLKTGAAQWLSDQTFGLMGLKHLPIIATIALITLFNILIHLGFASATSLASALIPVFISLTSTLNLGDHAIGFVLIQQFVISFGFLLPVSAPQNMLAYGTGTFTVKNFLKTGIPLTIVGYILVIVFSLTYWKWLGLV
>NZ_CP043847.1|WP_080395203.1|1133506_1134454_-|malate-dehydrogenase
MLMVNRRKISIIGAGHTGGTLAFILAQKELGDIVLIERQQSEGMAKGKALDILESGPIWGFDTSVHGSVNIEDIKDSDIVVMTAGIPRKSGMTREELVQTNEQIVRETALQIATYAPQSIIIVLTNPVDVMTYTAFKASGFPKERIIGQSGILDAARYRTFIAQELNVSVKDVNGFVLGGHGDTMLPLVNNTHINGIPVKHLISEEKIDQIVERTRKGGAEIVALLGQGSAYYAPATAIYETIDAIFNDRKRLLPSIAYLEGEYGCSDICFGVPTIIGYQGIEKIIEVDMNNDEYQQLQHSAQAVSKVKNSLKFK
>NZ_CP043847.1|WP_002438861.1|1134576_1134879_-|hypothetical-protein
MIKMNEDNRNKQIKFERNLITFPYLGFAFIVLLFNIFYTDVKITMVLFGLFFAYNLGMLFIAFIRHFKRTLILTLILTILSGIAFFVLLYVFGLNHDIFG
>NZ_CP043847.1|WP_002493526.1|1134891_1135818_-|GTP-binding-protein
MKNNKNEKLKITIVSGFLGSGKTTFLTHYINELLKIDEKITVIMNEFGSFDVDGNHLSELVKVYPLLNGCVCCDMKSDLVQQIEMLSHNHETDHIIIEATGIAHPIELIMACQDPRIVQFVERPHVVSIVDALRFLQRQQYTDSTKRLMEEQLEVSDVLVVNKLDLISVEDRDALKNQLNEVNKYSSKIYTTYGQVNIEELSQFRDQLVMTHTHSHHHGINSMQYTFTTAIDRQLFYQFILRMPDNVLRLKGYVQFKDEPNVTYEFQYSFGMPNYEVINGDYPLTIVLIGEQLDVNRLKNKLDVLQFS
>NZ_CP043847.1|WP_001830335.1|1136038_1136482_+|MarR-family-transcriptional-regulator
MSEQHNLKEQLCFSLYNAQRQVNRYYSNKVFKKYNLTYPQFLVLTILWDESPVNVKKVVTELALDTGTVSPLLKRMEQVDLIKRERSEVDQREVFIHLTDKSEMIRPELSNASEKVATASSLSKEEVKELNRLLGKVIDAFIETKEK
>NZ_CP043847.1|WP_017464496.1|1136724_1138419_-|thiol-reductant-ABC-exporter-subunit-CydC
MKSHIHFSIDRDLICAIMVGVLGGIVTLAMFFLSGYMITQSALGAPLYALMILVVSVKLFGFLRAITRYIERLLSHKTTFTMLRNVRVQFLKMLYPVVPDIYRRFNSSDLITKMISRVEALQNIYLRVYYPPIVIGLTAIVSVITMLFLSPLHALVITLSMLLTLWIVPWLSAKKARKLKQQVTQTQKTFLKRYYDYKEGHEELKRFNRSDDFKNTVSQSLRQFDDMQLKERRFLSIYDYLLNLIAMFSIFMCLVLGAQQIHDGQLNAIYITSIILMILTLFEQAVPMSNVAYYKADTDLALEEIHEVIVPKYKIPSEHTNLKRSQNLLLEIKNVTFKYEHQHHSTLKQINLTIEYGDKVAIIGPSGSGKSTLLHVLLGLYQIEEGEVRLNGKDMNSINDNDKYQTFNAMLQSQYIFDGSIRDNLFSEQSDDNLKKVLEDVGLEYLNLDSIVTLDGHNLSGGEAQRLSLARLLLRSSAGFWILDEPTTALDINNTEKIINLIESLSQTLIIATHDLEILPRFNKIIVMNDGEIIENGSYQELMQHDGYLKKVIEMNGNEMKFFN

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Crispr_ID: NZ_CP043847_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP043847_4

1429633-1429715

Orphan

Consensus_repeat	Method
CAGTGAAATTCTCTTTGTTGGGACCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP043847_4

>merge|NZ_CP043847|4|1429633-1429715|CRISPRCasFinder
CAGTGAAATTCTCTTTGTTGGGACCCATCCCCAACTTGCTTTGCTTGTTGAATTTCTCAGTGAAATTCTCTTTGTTGGGGCCC

>NZ_CP043847|4|4|1429633-1429715|CRISPRCasFinder
CAGTGAAATTCTCTTTGTTGGGACCC	ATCCCCAACTTGCTTTGCTTGTTGAATTTCT
CAGTGAAATTCTCTTTGTTGGGGCCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP043847.1\|WP_002437175.1\|1428381_1429005_+\|NDxxF-motif-lipoprotein	unknown	unknown	gnl\|CDD\|380196
NZ_CP043847.1\|WP_002447681.1\|1433083_1433593_-\|single-stranded-DNA-binding-protein	unknown	unknown	gnl\|CDD\|168659
NZ_CP043847.1\|WP_001832461.1\|1431684_1431939_-\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	unknown	unknown	gnl\|CDD\|225170
NZ_CP043847.1\|WP_080395226.1\|1423908_1424673_-\|NADPH-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|380322
NZ_CP043847.1\|WP_002447697.1\|1426025_1426595_+\|peroxiredoxin	unknown	unknown	gnl\|CDD\|211789
NZ_CP043847.1\|WP_017464680.1\|1429223_1429601_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043847.1\|WP_080032986.1\|1429171_1429270_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043847.1\|WP_001831361.1\|1436711_1436915_-\|DUF951-domain-containing-protein	unknown	unknown	gnl\|CDD\|377606
NZ_CP043847.1\|WP_002473809.1\|1432160_1432421_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043847.1\|WP_001831354.1\|1432796_1433039_-\|30S-ribosomal-protein-S18	unknown	unknown	gnl\|CDD\|178997
NZ_CP043847.1\|WP_002455897.1\|1420396_1421062_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043847.1\|WP_080395227.1\|1430576_1431242_-\|LysE-family-translocator	unknown	unknown	gnl\|CDD\|224199
NZ_CP043847.1\|WP_001831345.1\|1433615_1433912_-\|30S-ribosomal-protein-S6	unknown	unknown	gnl\|CDD\|179034
NZ_CP043847.1\|WP_017464677.1\|1435602_1436700_-\|redox-regulated-ATPase-YchF	unknown	unknown	gnl\|CDD\|236583
NZ_CP043847.1\|WP_002473337.1\|1424801_1425581_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226480
NZ_CP043847.1\|WP_017464678.1\|1435178_1435370_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043847.1\|WP_002493871.1\|1422398_1423787_+\|L-cystine-transporter	unknown	unknown	gnl\|CDD\|224736
NZ_CP043847.1\|WP_158171822.1\|1421187_1422090_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380149
NZ_CP043847.1\|WP_001829382.1\|1426609_1428133_+\|alkyl-hydroperoxide-reductase-subunit-F	unknown	unknown	gnl\|CDD\|237942
NZ_CP043847.1\|WP_002473790.1\|1429965_1430556_-\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|366010

Protein	Function_ID	Function_description	E-value
NZ_CP043847.1\|WP_002437175.1\|1428381_1429005_+\|NDxxF-motif-lipoprotein	gnl\|CDD\|380196	NF033193, lipo_NDxxF, NDxxF motif lipoprotein. Members of this family are lipoproteins, about 200 amino acids long in precursor form, found in Staphylococcus aureus, Bacillus cereus, and various other Firmicutes. The protein family is named for one of its several highly conserved motifs.	3.08114e-79
NZ_CP043847.1\|WP_002447681.1\|1433083_1433593_-\|single-stranded-DNA-binding-protein	gnl\|CDD\|168659	PRK06751, PRK06751, single-stranded DNA-binding protein; Provisional.	2.62434e-62
NZ_CP043847.1\|WP_001832461.1\|1431684_1431939_-\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	gnl\|CDD\|225170	COG2261, COG2261, Predicted membrane protein [Function unknown].	1.06396e-07
NZ_CP043847.1\|WP_080395226.1\|1423908_1424673_-\|NADPH-dependent-oxidoreductase	gnl\|CDD\|380322	cd02146, NfsA-like, nitroreductase similar to Escherichia coli NfsA. This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as an electron donor. Oxygen-insensitive nitroreductase, such as NfsA protein in Escherichia coli, catalyzes reduction of nitrocompounds using NADPH as electron donor.	9.91775e-92
NZ_CP043847.1\|WP_158171822.1\|1421187_1422090_+\|hypothetical-protein	gnl\|CDD\|380149	NF012181, MSCRAMM_SdrD, MSCRAMM family adhesin SdrD. Features of this protein family include a YSIRK-type signal peptide at the N-terminus and a variable-length C-terminal region of Ser-Asp (SD) repeats followed by an LPXTG motif for surface immobilization by sortase.	0.000368051
NZ_CP043847.1\|WP_002447697.1\|1426025_1426595_+\|peroxiredoxin	gnl\|CDD\|211789	TIGR03137, AhpC, peroxiredoxin. This peroxiredoxin (AhpC, alkylhydroperoxide reductase subunit C) is one subunit of a two-subunit complex with subunit F(TIGR03140). Usually these are found as an apparent operon. The gene has been characterized in Bacteroides fragilis, where it is important in oxidative stress defense. This gene contains two invariant cysteine residues, one near the N-terminus and one near the C-terminus, each followed immediately by a proline residue. [Cellular processes, Detoxification, Cellular processes, Adaptations to atypical conditions].	2.71478e-126
NZ_CP043847.1\|WP_001831354.1\|1432796_1433039_-\|30S-ribosomal-protein-S18	gnl\|CDD\|178997	PRK00391, rpsR, 30S ribosomal protein S18; Reviewed.	1.06497e-43
NZ_CP043847.1\|WP_080395227.1\|1430576_1431242_-\|LysE-family-translocator	gnl\|CDD\|224199	COG1280, RhtB, Putative threonine efflux protein [Amino acid transport and metabolism].	1.44257e-36
NZ_CP043847.1\|WP_001831345.1\|1433615_1433912_-\|30S-ribosomal-protein-S6	gnl\|CDD\|179034	PRK00453, rpsF, 30S ribosomal protein S6; Reviewed.	4.8221e-36
NZ_CP043847.1\|WP_002473337.1\|1424801_1425581_+\|hypothetical-protein	gnl\|CDD\|226480	COG3971, COG3971, 2-keto-4-pentenoate hydratase [Secondary metabolites biosynthesis, transport, and catabolism].	2.43495e-53
NZ_CP043847.1\|WP_017464677.1\|1435602_1436700_-\|redox-regulated-ATPase-YchF	gnl\|CDD\|236583	PRK09601, PRK09601, redox-regulated ATPase YchF.	0
NZ_CP043847.1\|WP_002493871.1\|1422398_1423787_+\|L-cystine-transporter	gnl\|CDD\|224736	COG1823, COG1823, Predicted Na+/dicarboxylate symporter [General function prediction only].	0
NZ_CP043847.1\|WP_001831361.1\|1436711_1436915_-\|DUF951-domain-containing-protein	gnl\|CDD\|377606	pfam06107, DUF951, Bacterial protein of unknown function (DUF951). This family consists of several short hypothetical bacterial proteins of unknown function. Structural modelling suggests this domain may bind nucleic acids.	8.08727e-28
NZ_CP043847.1\|WP_001829382.1\|1426609_1428133_+\|alkyl-hydroperoxide-reductase-subunit-F	gnl\|CDD\|237942	PRK15317, PRK15317, alkyl hydroperoxide reductase subunit F; Provisional.	0
NZ_CP043847.1\|WP_002473790.1\|1429965_1430556_-\|histidine-phosphatase-family-protein	gnl\|CDD\|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	2.71664e-46

>NZ_CP043847.1|WP_017464680.1|1429223_1429601_+|hypothetical-protein
MKVRLTFIILAILSTIGLVLVLAKYPTGPHTINYNEPYTVLIAITTIVIMALPTLILGIFNHLACRIISAILQISALMMWGFLVIISLIMGQFVIMLMASLTILALLVSSIVTLSVHPSTSDKIN
>NZ_CP043847.1|WP_080032986.1|1429171_1429270_-|hypothetical-protein
MVDSIAKIINVKRTFIMIFLISFYLEKIYMLY
>NZ_CP043847.1|WP_002437175.1|1428381_1429005_+|NDxxF-motif-lipoprotein
MKKRVITYLILALSLTLAACSNTNDNNNQEHHSNAHAPKNAKTLKEKDIFSSNKKGQKISEKEMKQALEKYLQANSDVLDNKYVMQHKLDKQSDSNPKITESQADRLSKLSNLAVKNDLHFKKFIKNNHIPEEYKDPTDRIINYFHALNSTISNVDEDIEKLNYQPQNSINVVDVPTKYSGDVNKKQQDKITTFLKKKGIDTEVFNK
>NZ_CP043847.1|WP_001829382.1|1426609_1428133_+|alkyl-hydroperoxide-reductase-subunit-F
MLNADLKQQLQQLLELMEGDVEFVASLGSDDKSNELKELLNEIAEMSAHITITEKSLKRTPSFSVNRPGEETGITFAGIPLGHEFNSLVLAILQVSGRAPKEKQSIIDQIKGLEGPFHFETFVSLTCQKCPDVVQALNLMSVINPNITHTMIDGAVFREESENIMAVPAVFLDGQEFGNGRMTVQDILTKLGSTQDASEFNDKDPYDVLIVGGGPASGSAAIYTARKGLRTGIVADRIGGQVNDTAGIENFITVKETTGSEFSSNLAEHIAQYDIDTMTGIRATNIEKTDSAIRVTLENDAVLESKTVIISTGASWRKLNIPGEDRLINKGVAFCPHCDGPLFENKDVAVIGGGNSGVEAAIDLAGIVKHVTLFEYASELKADSVLQERLRSLPNVDIKTSAKTTEVIGDDYVTGISYEDMTTGESQVVNLDGIFVQIGLVPNTSWLQNAVELNERGEVMINRDNATNVPGIFAAGDVTDQKNKQIIISMGAGANAALNAFDYIIRN
>NZ_CP043847.1|WP_002447697.1|1426025_1426595_+|peroxiredoxin
MSLINKEILPFTAQAYDPKKDEFKEVTQEDLKGSWNVVCFYPADFSFVCPTELEDLQNQYAKLQELGVNVYSVSTDTHFVHKAWHDHSDAISKLEYSMIGDPSQTITRNFDVLDEESGLAQRGTFIIDPDGVVQAAEINADGIGRDASTLVNKIKAAQYVRQHPGEVCPAKWEEGSESLQPGLDLVGKI
>NZ_CP043847.1|WP_002473337.1|1424801_1425581_+|hypothetical-protein
MTLTNKEVAKVLFKAYRYKKPIDFISENYQLSEEEAYLVQEKLIDQLTFKDHSTVTGYKVSMTSKATQAIANTSEPAYGTLLSNQIVNDGASVSLSELFSPLLEPEIIFIVQEDLPYDADLETIRYHTRIAPGIEIPDARYKNWFPNFTLSDLISDNTATGLVVVGDPVDGLDYDAFANVHLNLYKDDKCIATGESSEVLGNPLNAIHWLIKKLHTHGKQLKKGDIISSGTFISPLKLEYGTYRAEYSGIGKVSFSVNK
>NZ_CP043847.1|WP_080395226.1|1423908_1424673_-|NADPH-dependent-oxidoreductase
MGIVSDYVYELMKQHHSVRKFKNQPLSSETVEKLVEAGQSASTSSYLQTYSIIGVEDPSIKARLKEVSGQPYVLDNGYLFVFVLDYYRHHLVDEVAASNMETSYGSAEGLLVGTIDVALVAQNMAVAAEDMGYGIVYLGSLRNDVARVREILNLPDYTFPLFGMAVGEPSDEENGSPKPRLPFKHIFHKDQYDANQHQQRKELEAYDQVVSEYYKERTNGVRTENWSQQIETFLGRKTRLDMLDELKKAGFIQR
>NZ_CP043847.1|WP_002493871.1|1422398_1423787_+|L-cystine-transporter
MEILFTVINVIVLLVFLVMLNIMARKHVSFPKRVFTALGIGIVFGIVLHLIYGAESKTLEQSTDWFSIVGDGYVALLQMIVMPLIFISIVAAFSKIQIGEKFAKIGSYIFMFLIGTVAIAAIVGIFYALIFGLDASSIDLGSAEHSRGTEISKQAKDLTANTLPQQILEVFPSNPFLDFTGQRTTSTIAVVIFATFVGFAYLRVARKQPEHGSILKRGIEAIYSIVMAIVTFVLRLTPYGILAIMASTLATSDFSAIWTLGKFLIASYAALITMYIIHLIILSVLGINPVKYVKKTIEVLIFAFTSRSSAGALPLNVQTQTKRLGVPEGIANFSATFGLSIGQNGCAGIYPAMLAVMVAPVANVEIDFQFVVTLIAVVIISSFGVAGVGGGATFASILVLSTLNLPVALAGVLISIEPLIDMGRTALNVNDSMLAGTGTARLTNHWDKKTFDSKDYGDLSAN
>NZ_CP043847.1|WP_158171822.1|1421187_1422090_+|hypothetical-protein
MLTKEFAQRVELSEKQVRKIVQHLEERGYYLSKTEYRGREATDFKEDDIELFTDIANKVKQTNSYDLAFEELEKEKDFLQVIVKDEDSQLPTDQNVAQLVEDLRSEIQKMREERQMLGQMINQVHQQQQELKELQTDITTKLDSNAQSLKSIQNSQEAIQSAQEQQSKDIAKANELKDSELRSHFDSMSNSASISQSNVVSQSTTASLSQSESVNDSISSSLSESNSITSESNTNSKSEIESKSTSTSESLSESESVSNSEKAESISHSQSTSATPSSQSTYQQQPKEEKKGFFARLFNL
>NZ_CP043847.1|WP_002455897.1|1420396_1421062_+|hypothetical-protein
MEFKVIESAKDPLFNEALKLYDDKLDIGLDEDSKIFKRSLENNKTENDYAFIVGIENQTVVSLATAHYEATTNSAFLIYLIAKESPNHDERMSLTLEAIEKQLNLLSQEVHNRDINFIMLEVPKEPSTANIDDKLRNALEHRRQFLFENQFEKQDDIDYIHPNQNQKETPQKVDLFIKANIELTKDIYGTSVKSNYILKYVFANGISREIIYPLLKEMNLR
>NZ_CP043847.1|WP_002473790.1|1429965_1430556_-|histidine-phosphatase-family-protein
MEIYLVRHGESQSNYDNKHGYLYFCGQLDIPLTERGIKSAKELSVYFKNKYIDNVYVSDLKRTRQTYEELFPYDIPTMYTKTLRERSLGVFEGKNKEEVCKDKRFEKYFRDPNYKYFRHSFSQKAPQGESYQDVYDRVVTFIENELNQQQRRVVIVAHQVVIRCFFVYFKMITKEEALATEIHNCYPYLIKNEMKF
>NZ_CP043847.1|WP_080395227.1|1430576_1431242_-|LysE-family-translocator
MNCKMTSRRFLMDSLITFIIITLLIIIVPGPDFIIVMKNTINSSKMNGFMAAFGITTGHILYSSLAIFGIIYILTSLHFVFLTIKILGACYLIYLGIKSILSAHSSVDFSKQALADVRNVSYITSFRQGFLSTSLNPKALLFYVSIFPQFLSNGNIHMKSEVALFAFSVVVVICLWFLFCVFIFQYIKLLFSRPRFKAIFDYIVGFVLIGLSINLLLSKSS
>NZ_CP043847.1|WP_001832461.1|1431684_1431939_-|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein
MFGLIGMIIVGGIIGWIAGLILGKDVPGGILGNIIAGIVGSWVGTMILGEWGPQLGKIHIFPALLGSIILIFIISLILKALRKK
>NZ_CP043847.1|WP_002473809.1|1432160_1432421_+|hypothetical-protein
MQHKNKFQRINQIIQAIGFLSFLAILTIITLNFFIKGHLHGHFEIGFNIQSNQVYVVTTLIMVTIICTILSAILNTLSNKKQNYKH
>NZ_CP043847.1|WP_001831354.1|1432796_1433039_-|30S-ribosomal-protein-S18
MAGGPRRGGRRRKKVCYFTANGITHIDYKDTELLKRFISERGKILPRRVTGTSAKYQRMLTTAIKRARHMALLPYVKEEQ
>NZ_CP043847.1|WP_002447681.1|1433083_1433593_-|single-stranded-DNA-binding-protein
MLNRVVLVGRLTKDPEYRTTPSGVSVATFTLAVNRTFTNAQGEREADFINCVVFRRQAENVNNYLSKGSLAGVDGRIQSRSYENQEGRRIFVTEVVCDSVQFLEPKNAQQGGQRSQNNNFQDYGQGFGGQQSGQNTSYNNNNSSNSNQSDNPFANANGPIDISDDDLPF
>NZ_CP043847.1|WP_001831345.1|1433615_1433912_-|30S-ribosomal-protein-S6
MRTYEIMYIVRPNIEEDAKKALVERFNGILASEGSEVLEEKDWGKRRLAYEINDFKEGFYNIVRIKTDNNKSTDEFQRLAKINDDIIRYIVIREDQDK
>NZ_CP043847.1|WP_017464678.1|1435178_1435370_+|hypothetical-protein
MRLNLDWNKDFQEFQDILNSGIHPEWLYYAKANLVLEPAYTGEGKQFFSTQDIIKASKIIPFF
>NZ_CP043847.1|WP_017464677.1|1435602_1436700_-|redox-regulated-ATPase-YchF
MALTAGIVGLPNVGKSTLFNAITKAGALAANYPFATIDPNVGIVEVPDSRLIKLEEMVQPKKTIPTTFGFTDIAGIVKGASKGEGLGNKFLSHIREVDAICQVVRAFDDENVTHVSGRVNPLDDIEVINMELVLADLESVEKRLPKIEKMARQKDKTAEMELRILTQIKEALEDGKPVRSIDFNEDDQKWVNQVQLLTSKKMLYIANVGEDEIGDKDNDKVKAIREYAANEDSEVIVISAKIEEEIATLDDEDKEMFLEDLGIEEPGLDRLIRTTYDLLGLSTYFTAGVQEVRAWTFKQGMTAPQCAGIIHTDFERGFIRAEVTSYEDYVQHGGENGAKEAGRQRLEGKDYIMQDGDIVHFRFNV
>NZ_CP043847.1|WP_001831361.1|1436711_1436915_-|DUF951-domain-containing-protein
MTSKYGINDIVEMKKPHACGTNRFKIIRMGADIRIKCEHCQRSVMIPRQVFNKKMKKVLESHQDKES

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP043847_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP043847_5

1678565-1678648

Orphan

Consensus_repeat	Method
AAGGCAAGTTGGGGTTCGGGGCCCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP043847_5

>merge|NZ_CP043847|5|1678565-1678648|CRISPRCasFinder
AAGGCAAGTTGGGGTTCGGGGCCCCAACATAGAGAATTTCACCGGGAAATTCAACGGATAAGGCAAGTTGGGGTTCGGGGCCCC

>NZ_CP043847|5|5|1678565-1678648|CRISPRCasFinder
AAGGCAAGTTGGGGTTCGGGGCCCC	AACATAGAGAATTTCACCGGGAAATTCAACGGAT
AAGGCAAGTTGGGGTTCGGGGCCCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP043847.1\|WP_002494874.1\|1683771_1684647_+\|5'-nucleotidase,-lipoprotein-e(P4)-family	unknown	unknown	gnl\|CDD\|225305
NZ_CP043847.1\|WP_017464356.1\|1674185_1675373_+\|betaine/proline/choline-family-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213262
NZ_CP043847.1\|WP_017464360.1\|1688339_1688915_+\|dihydroxyacetone-kinase-subunit-L	unknown	unknown	gnl\|CDD\|274099
NZ_CP043847.1\|WP_002473493.1\|1683235_1683664_+\|FosB-family-fosfomycin-resistance-bacillithiol-transferase	unknown	unknown	gnl\|CDD\|179740
NZ_CP043847.1\|WP_002467644.1\|1687322_1688285_+\|dihydroxyacetone-kinase-subunit-DhaK	unknown	unknown	gnl\|CDD\|237724
NZ_CP043847.1\|WP_002458095.1\|1686203_1687307_+\|glycerol-dehydrogenase	unknown	unknown	gnl\|CDD\|181843
NZ_CP043847.1\|WP_002473486.1\|1675369_1676005_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224095
NZ_CP043847.1\|WP_017464359.1\|1684933_1685899_+\|biotin-synthase-BioB	unknown	unknown	gnl\|CDD\|235755
NZ_CP043847.1\|WP_080395168.1\|1678736_1680302_-\|YfcC-family-protein	unknown	unknown	gnl\|CDD\|224207
NZ_CP043847.1\|WP_002498100.1\|1671030_1671570_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380063
NZ_CP043847.1\|WP_080395177.1\|1669205_1670564_+\|branched-chain-amino-acid-transport-system-II-carrier-protein	unknown	unknown	gnl\|CDD\|283235
NZ_CP043847.1\|WP_059279802.1\|1677673_1678432_+\|esterase-family-protein	unknown	unknown	gnl\|CDD\|223700
NZ_CP043847.1\|WP_001830522.1\|1681421_1682423_-\|ornithine-carbamoyltransferase	unknown	unknown	gnl\|CDD\|235269
NZ_CP043847.1\|WP_001830485.1\|1682907_1683132_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|184224
NZ_CP043847.1\|WP_002473392.1\|1672600_1673566_+\|3-hydroxybutyryl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|168796
NZ_CP043847.1\|WP_002473470.1\|1676985_1677633_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224095
NZ_CP043847.1\|WP_002498098.1\|1673562_1674051_+\|thioesterase	unknown	unknown	gnl\|CDD\|372545
NZ_CP043847.1\|WP_158171856.1\|1676023_1676983_+\|osmoprotectant-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270326
NZ_CP043847.1\|WP_001830533.1\|1680466_1681399_-\|carbamate-kinase	unknown	unknown	gnl\|CDD\|237071
NZ_CP043847.1\|WP_080395169.1\|1671698_1672601_+\|3-keto-5-aminohexanoate-cleavage-protein	unknown	unknown	gnl\|CDD\|377562

Protein	Function_ID	Function_description	E-value
NZ_CP043847.1\|WP_002494874.1\|1683771_1684647_+\|5'-nucleotidase,-lipoprotein-e(P4)-family	gnl\|CDD\|225305	COG2503, COG2503, Predicted secreted acid phosphatase [General function prediction only].	7.87411e-102
NZ_CP043847.1\|WP_017464356.1\|1674185_1675373_+\|betaine/proline/choline-family-ABC-transporter-ATP-binding-protein	gnl\|CDD\|213262	cd03295, ABC_OpuCA_Osmoprotection, ATP-binding cassette domain of the osmoprotectant transporter. OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	2.23134e-153
NZ_CP043847.1\|WP_017464360.1\|1688339_1688915_+\|dihydroxyacetone-kinase-subunit-L	gnl\|CDD\|274099	TIGR02365, dha_L_ycgS, dihydroxyacetone kinase, phosphoprotein-dependent, L subunit. Two types of dihydroxyacetone kinase (glycerone kinase) are described. In yeast and a few bacteria, e.g. Citrobacter freundii, the enzyme is a single chain that uses ATP as phosphoryl donor and is designated EC 2.7.1.29. By contract, E. coli and many other bacterial species have a multisubunit form (EC 2.7.1.-) with a phosphoprotein donor related to PTS transport proteins. This family represents the subunit homologous to the E. coli YcgS subunit.	3.97648e-81
NZ_CP043847.1\|WP_002473493.1\|1683235_1683664_+\|FosB-family-fosfomycin-resistance-bacillithiol-transferase	gnl\|CDD\|179740	PRK04101, PRK04101, metallothiol transferase FosB.	2.76231e-93
NZ_CP043847.1\|WP_002467644.1\|1687322_1688285_+\|dihydroxyacetone-kinase-subunit-DhaK	gnl\|CDD\|237724	PRK14481, PRK14481, dihydroxyacetone kinase subunit DhaK; Provisional.	0
NZ_CP043847.1\|WP_002458095.1\|1686203_1687307_+\|glycerol-dehydrogenase	gnl\|CDD\|181843	PRK09423, gldA, glycerol dehydrogenase; Provisional.	0
NZ_CP043847.1\|WP_002473486.1\|1675369_1676005_+\|ABC-transporter-permease	gnl\|CDD\|224095	COG1174, OpuBB, ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism].	3.39157e-73
NZ_CP043847.1\|WP_017464359.1\|1684933_1685899_+\|biotin-synthase-BioB	gnl\|CDD\|235755	PRK06256, PRK06256, biotin synthase; Validated.	0
NZ_CP043847.1\|WP_080395168.1\|1678736_1680302_-\|YfcC-family-protein	gnl\|CDD\|224207	COG1288, COG1288, Predicted membrane protein [Function unknown].	0
NZ_CP043847.1\|WP_002498100.1\|1671030_1671570_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|380063	pfam17937, TetR_C_28, Tetracyclin repressor-like, C-terminal domain. TetR family regulators are involved in the transcriptional control of multidrug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. The TetR proteins identified in overm ultiple genera of bacteria and archaea share a common helix-turn-helix (HTH) structure in their DNA-binding domain. However, TetR proteins can work in different ways: they can bind a target operator directly to exert their effect (e.g. TetR binds Tet(A) gene to repress it in the absence of tetracycline), or they can be involved in complex regulatory cascades in which the TetR protein can either be modulated by another regulator or TetR can trigger the cellular response. TetR regulates the expression of the membrane-associated tetracycline resistance protein, TetA, which exports the tetracycline antibiotic out of the cell before it can attach to the ribosomes and inhibit protein synthesis. TetR blocks transcription from the genes encoding both TetA and TetR in the absence of antibiotic. The C-terminal domain is multi-helical and is interlocked in the homodimer with the helix-turn-helix (HTH) DNA-binding domain. This entry represents the C-terminal domain present in CgmR (C. glutamicum multidrug-responsive transcriptional repressor), previously called CGL2612 protein. CgmR (CGL2612) from Corynebacterium glutamicum is a multidrug-resistance-related transcription factor belonging to the TetR family. It regulates expression of the immediately upstream gene cgmA (cgl2611) by binding to the operator cgmO in the cgmA promoter. The cgmA gene encodes a permease belonging to the major facilitator superfamily, a protein family composed of bacterial multidrug exporters, and the pair of CgmR and CgmA confers multidrug resistance on C. glutamicum.	2.17589e-28
NZ_CP043847.1\|WP_080395177.1\|1669205_1670564_+\|branched-chain-amino-acid-transport-system-II-carrier-protein	gnl\|CDD\|283235	pfam05525, Branch_AA_trans, Branched-chain amino acid transport protein. This family consists of several bacterial branched-chain amino acid transport proteins which are responsible for the transport of leucine, isoleucine and valine via proton motive force.	1.5994e-153
NZ_CP043847.1\|WP_059279802.1\|1677673_1678432_+\|esterase-family-protein	gnl\|CDD\|223700	COG0627, COG0627, Predicted esterase [General function prediction only].	2.52088e-44
NZ_CP043847.1\|WP_001830522.1\|1681421_1682423_-\|ornithine-carbamoyltransferase	gnl\|CDD\|235269	PRK04284, PRK04284, ornithine carbamoyltransferase; Provisional.	0
NZ_CP043847.1\|WP_001830485.1\|1682907_1683132_+\|hypothetical-protein	gnl\|CDD\|184224	PRK13667, PRK13667, hypothetical protein; Provisional.	0.00602145
NZ_CP043847.1\|WP_002473392.1\|1672600_1673566_+\|3-hydroxybutyryl-CoA-dehydrogenase	gnl\|CDD\|168796	PRK07066, PRK07066, L-carnitine dehydrogenase.	3.58987e-122
NZ_CP043847.1\|WP_002473470.1\|1676985_1677633_+\|ABC-transporter-permease	gnl\|CDD\|224095	COG1174, OpuBB, ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism].	2.20323e-68
NZ_CP043847.1\|WP_002498098.1\|1673562_1674051_+\|thioesterase	gnl\|CDD\|372545	pfam13279, 4HBT_2, Thioesterase-like superfamily. This family contains a wide variety of enzymes, principally thioesterases. These enzymes are part of the Hotdog fold superfamily.	4.95199e-32
NZ_CP043847.1\|WP_158171856.1\|1676023_1676983_+\|osmoprotectant-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270326	cd13608, PBP2_OpuCC_like, Substrate-binding protein OpuCC of ABC-type osmoregulatory transporter and related proteins; the type 2 periplasmic-binding protein fold. This subfamily includes the periplasmic substrate-binding protein OpuCC of the ABC transporter OpuC (where Opu is osmoprotectant uptake), which can recognize a broad spectrum of compatible solutes, and its paralog OpuBC that can solely bind choline. To counteract the efflux of water, many microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	4.69716e-164
NZ_CP043847.1\|WP_001830533.1\|1680466_1681399_-\|carbamate-kinase	gnl\|CDD\|237071	PRK12353, PRK12353, putative amino acid kinase; Reviewed.	0
NZ_CP043847.1\|WP_080395169.1\|1671698_1672601_+\|3-keto-5-aminohexanoate-cleavage-protein	gnl\|CDD\|377562	pfam05853, BKACE, beta-keto acid cleavage enzyme. BKACE, beta-keto acid cleavage enzyme plays, a role in lysine degradation. In certain instances it catalyzes the conversion of 3-keto-5-aminohexanoate and acetyl-CoA into acetoacetate and 3-aminobutyryl-CoA. The family is found to have at least 14 slightly different potential new enzymatic activities, all of which can therefore be designated as beta-keto acid cleavage enzymes.	1.83491e-124

>NZ_CP043847.1|WP_059279802.1|1677673_1678432_+|esterase-family-protein
MAHITLNYLSKTLGMHQTINVILPEDKSYFDTNENAQPLKTMLLLHGLSSDTSSYMRYTSIERYANTHQLAVVMPNADHSFYSNMAYGHSYYDYILEVYDYVHQIFPLSKKREDNFIAGHSMGGYGAIKFALTQSHRFSKAAMLSAAFDVSMIGQYKWYDFTPEAIVGDMQHIAGTSFDPYYLVEQAIDKGKRLPQLYITCGTEDELYQGNIDFVNYLDEKGIPYQFKKAPGNHDYAFWDKAIEDVIDRFTS
>NZ_CP043847.1|WP_002473470.1|1676985_1677633_+|ABC-transporter-permease
MEGNLIQQLVHYYQMNFGYLWELFVNHLLMSVYGVLLACLVGIPLGIIIARFGKLSGVIITIANIIQTVPVIAMLAILMLSMGLGMNTVIFTVFLYALLPIIKNTYTGINEVDPNIKDAGKGMGMTRNQVLTMIELPLSLSVIIGGIRIALVVAIGVVAVGSFIGAPTLGDIVIRGTNATDGTLFILAGSIPIVIIVILIDVLLRLLEKKLDPAT
>NZ_CP043847.1|WP_158171856.1|1676023_1676983_+|osmoprotectant-ABC-transporter-substrate-binding-protein
MKNYKKYLIVLVLCLTVLYGCNLPGLKNSHSDDDVRITSLGTSESQIISHMLRLLIEHDTKGEIKPTLINNLGSSTIQHNAVTSGQANMSGTRYTGTDLTGALKEDPIKDPKKAMKATQEGFEKKYHQTFFNSYGFENTYSLIVTKETAKKYHLETVSDLEKHAKDLRVGMDSSWMDRKGDGYPAFKKEYGYSFGTVRPMQIGLVYDALNSGKLDVAVGYSTDGRISAYDLKVLKDDRRFFPPYDASPLASDQLLKEKPELKPIVKKLEGKISTEQMQELNYQADGKGKEPATVAEDFLKKHHYFEDDKDKKDKQKGGQ
>NZ_CP043847.1|WP_002473486.1|1675369_1676005_+|ABC-transporter-permease
MIKFISEHSGMLFAKTFEHLYISIMALIIAMIVAVPLGILLSKKEKLSKVSLTIAGVLQTIPTLAVLALMIPLFGVGKTPAIIALFLYVLLPILNNTIIGIQNIDPNLREAGRSMGMTNFQLMKDVELPLALPLILSGIRLSSVYVISWATLASYVGAGGLGDFIFNGLALFEPSMIITATILVTAIALIVDYGLSLIEKWIVPKGLKVSR
>NZ_CP043847.1|WP_017464356.1|1674185_1675373_+|betaine/proline/choline-family-ABC-transporter-ATP-binding-protein
MLSIKNLSKVYAGGKKAVDNMTIDIESGDFIAFIGTSGSGKTTALRMINRMIESTEGEITIDGKNIKNLNPVELRRSIGYVIQQIGLMPHMTVKENIVLVPKLLKWSQEKKDEKARELIRLVDLPEEYLDRYPSELSGGQQQRIGVVRALAAEQDIILMDEPFGALDPITRDTLQDLVKKLQQQLGKTFIFVTHDMDEAIKLADKICIMTNGQVVQYDTPDNILRSPANDFVRDFIGQNRLIQDRPNIRTVKDAMIKPVTVHVDHSLNDAVNIMREKRVDTIFVVGNDEHLLGYLDIEDINEGLRHHKELIDTMQRDIYRVRIDSKLQDSVRTILKRNVRNVPVVDSDNKKLLGLVTRANLVDIVYDSIWGELDSDKNDNHSGIVEPGSTGVETS
>NZ_CP043847.1|WP_002498098.1|1673562_1674051_+|thioesterase
MMNQQYVFHTKVHRDWVDHNGHLNDAMYNRIFSDTTDDWLGHLGLTIDAIQSYQYTVFTLENHVMFLNEMKENEDVIVKVHLHDYDSKRLHVLMEMFNADDDLCATYEVMLMGIDTTSGRPSAFPNDILNNIEHYYNIENVEMTSQYIGHRIGIKKKPKSKE
>NZ_CP043847.1|WP_002473392.1|1672600_1673566_+|3-hydroxybutyryl-CoA-dehydrogenase
MKFAVVGTGVIGSGWITRMLAHGHEVIATDPSEGAYERMLTQVKQNWPYAQEMGLAENASIKNLTFTPHLEEAVKDADHIQENVPEVEEIKDAVLKEIDFYAKPEATIGSSTSGIMPSELQANLSHPERLVVAHPFHPVYILPLVEIVPGKQTSEETTVKAERIYESIGMDVLHVRHEIEGHIADRLMEALWRESLHIVNDGIATTEEVDKAFTHAAGLRYAQYGPFMTFHLAGGEGGMRHMLKQFGPALKKPWTKLIAPELTDDLYHKVVNGSEASSQGYTMSELDQKRNEFLIKVKELAEQYWPSDSKAMKKSNGAKLQ
>NZ_CP043847.1|WP_080395169.1|1671698_1672601_+|3-keto-5-aminohexanoate-cleavage-protein
MLMMQKVVLTAAITGAGDTIHKNENVPVTPQELADSAIKCARAGATVAHIHVRDPETGGVSHDPELYAETVRLIREADEDIVINVTSGGGGDFIPSLEHPETGGEGTWIQTPEERFKPIGDLLPEMCTLDCGSVNMGDAIYLSPASWLRKQAQMVKDAGVKPELECFDTGHVSFAKQMIEEGLIEGNPMFQFCLGIPWGAENDTETIEYLKSRIPENAHWSAFGIGKMQLPTVREVAQRGGNVRVGLEDNIYLRKGVKATNEALVEEAKRILAELDIEPLTPAEAREKFNLRNPHGKGGK
>NZ_CP043847.1|WP_002498100.1|1671030_1671570_+|TetR/AcrR-family-transcriptional-regulator
MPRTSKRQLILESAAAIINEKGADYLTLDAVAQRAEISKGGLFYHFKSKDELIKELVNYANNLYRDNVNQHIGNEKNEKGQWLNAFIEATRAHRTDNAPITSGMLAAQGTNRSLLSPLKTSYQEWQYQITHDGLDEVDATIIRLAVDGLWLSEIFGISAIDEDMREKVIERLKMQIEKN
>NZ_CP043847.1|WP_080395177.1|1669205_1670564_+|branched-chain-amino-acid-transport-system-II-carrier-protein
MKNKLTLKENLFIGSMLFGLFFGAGNLIFPIHLGQTAGANVWTANLGFLITAIGLPFLGIIAIGVSKTNGVFEISSRISKIYGYLFTIGLYLVIGPFFALPRLATTSFEIAFSPFISSGTAQVLLPIFSILFFGAAWLFSRKPSKILDYIGKFLNPVFLILLGIVVVLAFIRPMGGISHAPVSADYSNSVLLKGFIDGYNTLDALASLAFGIIIVTTIKKLGITNPNTIAKETLKSGTISIIAMGVIYTLLALMGTMSLGRFKVSENGGIALAQIAQHYLGDYGIIILSLIIIVACLKTAIGLITAFSETFTELFPKSNYLWLATGVSILACIFANVGLTKIIMYSTPVLMFIYPLAITLILLALLSPLFKHSKIVYRFTTLFTMVAAFVDGVKASPEFFVNTKFAQTIIGFGENYLPFFNIGMGWIVPALIGFIIGIIVYFMTAKKSSHVQ
>NZ_CP043847.1|WP_080395168.1|1678736_1680302_-|YfcC-family-protein
MKPLEQAINDNKKKKRFNFRMPGAFMILFILTVVAVIATWIIPAGAYSKLSYEPSSQELKIVNPHHQIKKVPGTQKELDRLGVKIKIEQFKSGAINKPVSIPNTYERLKQHPAGLDQITSSMVKGTIEAVDIMVFILVLGGLIGVVQASGSFESGLLALTQKTKGHEFMLIAFVSILMIIGGTLCGIEEEAVAFYPVLVPIFIALGYDSIVSVGAIFLASSVGSTFSTINPFSVVIASNAAGTTFTDGLYWRIGACIIGAIFVISYLFWYCKKIKKDPKSSYSYEDKAAFEKQWSVLHDDGSSEFTLRKKIILTLFVLPFPIMVWGVMTQGWWFPVMASAFLIFTIVIMFIAGTGQYGLGEKGTVDAFVNGASSLVGVSLIIGLARGINLVLNKGMISDTILHFSSSIVQHMSGPLFIIVLLFIFFCLGFIVPSSSGLAVLSMPIFAPLADTVGIPRFVIVTTYQFGQYAMLFLAPTGLVMATLQMLNMRYSHWLRFVWPVVAFVLIFGGGLLITQVLIYS
>NZ_CP043847.1|WP_001830533.1|1680466_1681399_-|carbamate-kinase
MAKIVVALGGNALGKSPQEQLELVKNTAKSLVGLITKGHEIVISHGNGPQVGSINLGLNYAAEHDQGPAFPFAECGAMSQAYIGYQLQESLQNELHSMGIDKQVVTLVTQVEVDEGDPAFNSPSKPIGLFYTKEEANRIQQEKGYQFVEDAGRGYRRVVPSPQPISIIELESIKTLVENDTLVIAAGGGGIPVIREQHDSFKGIDAVIDKDKTSALLGADIHCDQLIILTAIDYVYINYHTDQQQALKTTNIDTLKTYIEEEQFAKGSMLPKIESAISFIENNPNGSVLITSLNQLDAALEGKIGTLITK
>NZ_CP043847.1|WP_001830522.1|1681421_1682423_-|ornithine-carbamoyltransferase
MKNLRNRSFLTLLDFSRQEVEFLLTLSEDLKRAKYIGTEKPMLKNKNIALLFEKDSTRTRCAFEVAAHDQGAHVTYLGPTGSQMGKKETAKDTARVLGGMYDGIEYRGFSQRTVETLAQYSGVPVWNGLTDEDHPTQVLADFLTAKEVLKKEYADINFTYVGDGRNNVANALMQGAAIMGMNFHLVCPKELNPTEELLNRCERIATENGGNILITDDIDKGVKDSDVIYTDVWVSMGEPDEVWQERLKLLKPYQVNQALLEKTGNPNVIFEHCLPSFHNAETKIGQQIYEKYGISEMEVTDDVFESKASVVFQEAENRMHTIKAVMVATLGEF
>NZ_CP043847.1|WP_001830485.1|1682907_1683132_+|hypothetical-protein
MKVYKLNYQHHKDIVDDNVLTMFVTADNQDEVEAFAKKLHYKIEHLSPLTKKEFEDEKAKDSHYRLEHVDHYLN
>NZ_CP043847.1|WP_002473493.1|1683235_1683664_+|FosB-family-fosfomycin-resistance-bacillithiol-transferase
MEITSVNHICFSVSDLNTSIQFYKDILQGDLLVSGRTTAYLTIGHTWIALNQEKNIPRNEISHSYTHVAFSIDEEDFQKWIQWLKENQVNILKGRPRDIKDKKSIYFTDPDGHKIELHTGTLKDRMEYYKCEKTHMQFYDEF
>NZ_CP043847.1|WP_002494874.1|1683771_1684647_+|5'-nucleotidase,-lipoprotein-e(P4)-family
MNKLSKYIAIATLASTVTISAPIHTYACESHTKDNHNQTTQHQNDPDLGEQNVMAVSWYQNSAEAKALYLQGYNTAKYQLDEHIKKNKGKKKLAIALDLDETVLDNSPYQGYASMHDTSFPEGWHEWVAAAKAKPVYGAKSFLKYADKKGIDIYYISDRDKEKDFKATKENLKNIGLPQAKDNHILLKGKNDKSKASRRQQVEKNHKLVMLFGDNLLDFTDPKKSTAKEREKLVQKHEKDFGKKYIIFPNPMYGSWESTLYHNQYEISKNEKDELRKSSIKQFNPETGEVK
>NZ_CP043847.1|WP_017464359.1|1684933_1685899_+|biotin-synthase-BioB
MTLNLAQRVLNREPLTKEEALTIFESSELDTFDLLNEAYTVRKHYYGKKVKLNMILNAKSGICAEDCGYCGQSVKMKEKQRYALVEQDQIKEGAQVATENQIGTYCIVMSGRGPSNREVDHICETVEDIKKIHPQLKICACLGLTKEEQAKKLKAAGVDRYNHNLNTSERYHDEVVTTHTYEDRVRTVEMMKDNNISPCSGVICGMGESNEDIIDMAFALRAIDADSIPINFLHPIKGTKFGGLDLLSPMKCLRIIAMFRLINPTKEIRIAGGREVNLRSLQPLALKAANSIFVGDYLITGGQPNEEDYRMIEDLGFEIDS
>NZ_CP043847.1|WP_002458095.1|1686203_1687307_+|glycerol-dehydrogenase
MSKFIYQSPGRYVQGKGIVSSIAEETERLGSHALIIADEVVWNITEEKIKESFSANNNVDFEYEVFKGESSEEEIQRIAKQYKEKNIDVVIGLGGGKALDTGKAVAFELKASVIDFASTASMDAPTAAVSVIYNEDGSFSGYEFYPKNPDTVIVDSEIVAQAPVRLFASGMSDGLATLIEVESTLRRQGQNMFHGKPTLASLAIAQKCEEVIFEYGYSAYTSVENHIVTPQVDAVIEANTLLSGLGFENGGLAGAHAIHNGFTALEGDIHHLTHGEKVAYGILVQLVLENAPTEKFMKYKTFFDNINMPTTLEGLHIENTSYEELVQVGERALTPNDTFANLSDKITADEIADAILTVNDLSKSQFN
>NZ_CP043847.1|WP_002467644.1|1687322_1688285_+|dihydroxyacetone-kinase-subunit-DhaK
MKKLIQDKNTILKDMLDGITVSNNDVEVVSDTIVVRKHKKQSGVALVSGGGSGHEPAHAGFVAEGMLDAAVCGEIFTSPTPDKILDAIKAVDNGDGVLLVIKNYAGDVMNFEMAQEMAQMEDIKVESVIVRDDIAISDPEKRRGVAGTVFVHKYAGYLAEKGVALDEIKSKVEALLPDIKSIGMALTPPMVPTTGKNGFDIEDNQMEIGIGIHGEKGLHREDVQPINVIVERLLDQLYKEIEKKPLIVMVNGMGGTPLSELNIVTKYLDEQFNQNDIDVKQWFVGDYMTALDMQGFSITVLPFSEELSEALAAPTASKYF
>NZ_CP043847.1|WP_017464360.1|1688339_1688915_+|dihydroxyacetone-kinase-subunit-L
MNVADIKARLLDLENTFKEKESELTDLDRAIGDGDHGVNMVRGFEHLKEKIDDQSMQALFKSTGMTLMSNVGGASGPLYGFGFIKMASAVNDEIDHDNLKEVLKAFADGIQQRGKVELNEKTMYDVIERAREAVEKNETVDFDKLQSFANETKDMVATKGRASYFNEASKGYIDPGAQSSVYILNAIIGGE

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Crispr_ID: NZ_CP043847_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP043847_6

2144251-2144362

Orphan

Consensus_repeat	Method
TATAAGTGACTTAATTTACAAAATGTCCCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP043847_6

>merge|NZ_CP043847|6|2144251-2144362|CRISPRCasFinder
TATAAGTGACTTAATTTACAAAATGTCCCTCTATAATAATGATTAAACGAATTATAACACCTATTATATAGAGAATAAAGAGTATAAGTGACTTAATTTACAAAATGTCCCT

>NZ_CP043847|6|6|2144251-2144362|CRISPRCasFinder
TATAAGTGACTTAATTTACAAAATGTCCCT	CTATAATAATGATTAAACGAATTATAACACCTATTATATAGAGAATAAAGAG
TATAAGTGACTTAATTTACAAAATGTCCCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP043847.1\|WP_002494373.1\|2146443_2146896_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|179699
NZ_CP043847.1\|WP_077431438.1\|2140048_2140237_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043847.1\|WP_002474475.1\|2155021_2155552_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043847.1\|WP_017464755.1\|2149216_2149804_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043847.1\|WP_145356382.1\|2142713_2143325_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|376540
NZ_CP043847.1\|WP_017464756.1\|2150109_2151411_+\|Na+/H+-antiporter-NhaC-family-protein	unknown	unknown	gnl\|CDD\|224671
NZ_CP043847.1\|WP_002457260.1\|2151707_2152220_+\|SRPBCC-domain-containing-protein	unknown	unknown	gnl\|CDD\|369817
NZ_CP043847.1\|WP_002494369.1\|2138877_2139264_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043847.1\|WP_002494368.1\|2139423_2139873_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043847.1\|WP_158171918.1\|2134980_2136222_+\|plasmid-recombination-enzyme	unknown	unknown	gnl\|CDD\|366451
NZ_CP043847.1\|WP_017464758.1\|2153327_2154917_+\|PTS-transporter-subunit-EIIC	unknown	unknown	gnl\|CDD\|273925
NZ_CP043847.1\|WP_145356380.1\|2143372_2144230_-\|RepB-family-plasmid-replication-initiator-protein	unknown	unknown	gnl\|CDD\|227814
NZ_CP043847.1\|WP_021298942.1\|2137229_2137904_+\|IS6-family-transposase	unknown	unknown	gnl\|CDD\|225853
NZ_CP043847.1\|WP_002494371.1\|2147486_2147861_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043847.1\|WP_002511319.1\|2140983_2141352_+\|DUF3139-domain-containing-protein	unknown	unknown	gnl\|CDD\|371476
NZ_CP043847.1\|WP_002494367.1\|2140484_2140880_-\|DUF3139-domain-containing-protein	unknown	unknown	gnl\|CDD\|371476
NZ_CP043847.1\|WP_158171920.1\|2144780_2145989_-\|recombinase	unknown	unknown	gnl\|CDD\|366451
NZ_CP043847.1\|WP_158171919.1\|2141481_2141847_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043847.1\|WP_059224240.1\|2155853_2156489_+\|HAD-IA-family-hydrolase	unknown	unknown	gnl\|CDD\|319859
NZ_CP043847.1\|WP_021298942.1\|2147975_2148650_-\|IS6-family-transposase	unknown	unknown	gnl\|CDD\|225853

Protein	Function_ID	Function_description	E-value
NZ_CP043847.1\|WP_145356382.1\|2142713_2143325_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|376540	pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI. Within Neisseria gonorrhoeae NGO_0477, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteristic of the whole family.	2.16331e-09
NZ_CP043847.1\|WP_002494373.1\|2146443_2146896_+\|hypothetical-protein	gnl\|CDD\|179699	PRK03992, PRK03992, proteasome-activating nucleotidase; Provisional.	0.0097443
NZ_CP043847.1\|WP_017464756.1\|2150109_2151411_+\|Na+/H+-antiporter-NhaC-family-protein	gnl\|CDD\|224671	COG1757, NhaC, Na+/H+ antiporter [Energy production and conversion].	9.37925e-81
NZ_CP043847.1\|WP_002457260.1\|2151707_2152220_+\|SRPBCC-domain-containing-protein	gnl\|CDD\|369817	pfam08327, AHSA1, Activator of Hsp90 ATPase homolog 1-like protein. This family includes eukaryotic, prokaryotic and archaeal proteins that bear similarity to a C-terminal region of human activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1/p38). This protein is known to interact with the middle domain of Hsp90, and stimulate its ATPase activity. It is probably a general upregulator of Hsp90 function, particularly contributing to its efficiency in conditions of increased stress. p38 is also known to interact with the cytoplasmic domain of the VSV G protein, and may thus be involved in protein transport. It has also been reported as being underexpressed in Down's syndrome. This region is found repeated in two members of this family.	1.55893e-20
NZ_CP043847.1\|WP_158171918.1\|2134980_2136222_+\|plasmid-recombination-enzyme	gnl\|CDD\|366451	pfam01076, Mob_Pre, Plasmid recombination enzyme. With some plasmids, recombination can occur in a site specific manner that is independent of RecA. In such cases, the recombination event requires another protein called Pre. Pre is a plasmid recombination enzyme. This protein is also known as Mob (conjugative mobilisation).	3.89609e-75
NZ_CP043847.1\|WP_017464758.1\|2153327_2154917_+\|PTS-transporter-subunit-EIIC	gnl\|CDD\|273925	TIGR02005, PTS-IIBC-alpha, PTS system, alpha-glucoside-specific IIBC component. This model represents a family of fused PTS enzyme II B and C domains. A gene from Clostridium has been partially characterized as a maltose transporter, while genes from Fusobacterium and Klebsiella have been proposed to transport the five non-standard isomers of sucrose. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	0
NZ_CP043847.1\|WP_145356380.1\|2143372_2144230_-\|RepB-family-plasmid-replication-initiator-protein	gnl\|CDD\|227814	COG5527, COG5527, Protein involved in initiation of plasmid replication [DNA replication, recombination, and repair].	2.8648e-79
NZ_CP043847.1\|WP_021298942.1\|2147975_2148650_-\|IS6-family-transposase	gnl\|CDD\|225853	COG3316, COG3316, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	9.98395e-87
NZ_CP043847.1\|WP_002511319.1\|2140983_2141352_+\|DUF3139-domain-containing-protein	gnl\|CDD\|371476	pfam11337, DUF3139, Protein of unknown function (DUF3139). This family of proteins with unknown function appears to be restricted to Firmicutes.	9.28702e-06
NZ_CP043847.1\|WP_002494367.1\|2140484_2140880_-\|DUF3139-domain-containing-protein	gnl\|CDD\|371476	pfam11337, DUF3139, Protein of unknown function (DUF3139). This family of proteins with unknown function appears to be restricted to Firmicutes.	0.0003047
NZ_CP043847.1\|WP_158171920.1\|2144780_2145989_-\|recombinase	gnl\|CDD\|366451	pfam01076, Mob_Pre, Plasmid recombination enzyme. With some plasmids, recombination can occur in a site specific manner that is independent of RecA. In such cases, the recombination event requires another protein called Pre. Pre is a plasmid recombination enzyme. This protein is also known as Mob (conjugative mobilisation).	2.01529e-29
NZ_CP043847.1\|WP_059224240.1\|2155853_2156489_+\|HAD-IA-family-hydrolase	gnl\|CDD\|319859	cd16423, HAD_BPGM-like, uncharacterized subfamily of beta-phosphoglucomutase-like family, similar to uncharacterized Bacillus subtilis YhcW. This subfamily includes the uncharacterized Bacillus subtilis YhcW. It belongs to the beta-phosphoglucomutase-like family whose other members include Lactococcus lactis beta-PGM, a mutase which catalyzes the interconversion of beta-D-glucose 1-phosphate (G1P) and D-glucose 6-phosphate (G6P), Saccharomyces cerevisiae phosphatases GPP1 and GPP2 that dephosphorylate DL-glycerol-3-phosphate and DOG1 and DOG2 that dephosphorylate 2-deoxyglucose-6-phosphate, and Escherichia coli 6-phosphogluconate phosphatase YieH. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.31443e-51
NZ_CP043847.1\|WP_021298942.1\|2137229_2137904_+\|IS6-family-transposase	gnl\|CDD\|225853	COG3316, COG3316, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	9.98395e-87

>NZ_CP043847.1|WP_145356380.1|2143372_2144230_-|RepB-family-plasmid-replication-initiator-protein
MSGETVVYRNEMNLVPLRRFTSTEVDLFFTLCNKLKEQDTRKVIIPFEELKYLSNYYTRSQERFINDLEHVYDKMLNLTYVERNDRSFEKFVLFTSYKVDLDEECLSISVNPDLKHILNSITADFTKFELKEMTHLKSTYAKNMFRLLKQYKHTGYIKINIADFKNRLDIPKTYQMNDITKRVLKPIINELSSIFNNLNINKIKAKKGRKIEWLEFTFDAEKRIHNKRQPQMANIDKSRQYISREKTPRWLEERTYEKQIKNEYDPQLEKERKAFLKQLQLDWED
>NZ_CP043847.1|WP_145356382.1|2142713_2143325_+|helix-turn-helix-domain-containing-protein
MGMNKSKIAEIRKQKSLTQENLAEKSYVTVRTIQRMEAGEEVSSETLKSVSNALDVTVNELFESISSSDKEEEIMEISKEQQKQFNYRKNEFFTIRLITFGIIFVFLGLFGIFVGELEGLEQNIYRIIWIFALFLSLAIMYYFLNVFISKKLDKKYPMTIGMKNRNRKNEPVKNGWDFMARYWWIVFPIGGFLSWLIPELTGK
>NZ_CP043847.1|WP_158171919.1|2141481_2141847_+|hypothetical-protein
MKRLKIIILILSLVPIEFIGLFTDYQTGLLIGYIPFIIVAILISTSIFKFGLKNNISIIISRCIGTFLSWECVHWFMNIYDSSDYFKPLTTDIFALFLGAIHFIVIMLIYLVIYGFSHRNN
>NZ_CP043847.1|WP_002511319.1|2140983_2141352_+|DUF3139-domain-containing-protein
MKKILKILITSIIVIIITLTVWTFSVITYQKHKSEKIINHVIERKGWDKKIKNEKMSFNIMMGYAEKDIVFKDQPYSEYEYNVTPAPAPWTDDKEYKVWGETDLQKKDSYYKYLLESEPYRK
>NZ_CP043847.1|WP_002494367.1|2140484_2140880_-|DUF3139-domain-containing-protein
MKRKYKITGIIFIVLLIVLTLIFSIVHHYANVQKHEEAKLKQKVHHIFKQKGWEDKVKEEKNIFTFNTGDNDLQVTFKDEPYNTYTYSIDEDNKVYGNAVLKDEYDKDFDSKKKYKEYLRKMHFEEKYDLK
>NZ_CP043847.1|WP_077431438.1|2140048_2140237_+|hypothetical-protein
MENGIYQFYFSISISFTIFNIGMISNDKIKADSKIRKIFISLKNIKSITYPKIQNMIKRQIK
>NZ_CP043847.1|WP_002494368.1|2139423_2139873_-|hypothetical-protein
MKKLLSVFIASLLVLTGLSFSSINQGNTASAKTKYKTTITYKGQKYVYVGHYKHHFSKKEVKKVVKFSKGVHSGNKLVSAASKLSKNGYVKASSAIYKAFDFGLKNELKGSYFYTAAKKGTGVTISYDMYTATTGPNHTIAKNFKHSYN
>NZ_CP043847.1|WP_002494369.1|2138877_2139264_+|hypothetical-protein
MKKAIFSIIISLILVLTVTGCSNSSKEKPIKKSALEINPTSKAVNITINKKENNKPEKIGKVYRYKNNNAKEITNDGIKKDTKDTLIWKGVANKYDNVKDLLGESILYEVKYKNGDIKKFERKIKYTE
>NZ_CP043847.1|WP_021298942.1|2137229_2137904_+|IS6-family-transposase
MNYFRYKQFDKDVITVAVGYYLRYALSYRDISEILRERGVTVHHSTVYRWVQEYAPILYQIWKQKHKKAYYKWHVDETYIKIKGKWCYLYRAIDADGHTLDIWLRKQRDNHAAYAFIKRLIKQFGKPKMIITDQAPSTKIAMSKLIKDFKLNSNCHCTSKYLNNLIEQDHRHIKVRKISYQSINTAKNTIKGIECIYGLYKKNRRSLQIYGFSPCREISIMLAS
>NZ_CP043847.1|WP_158171918.1|2134980_2136222_+|plasmid-recombination-enzyme
MSYSIVRVSKVKSGTNTTGIQKHVQRENNNYENEDIDHSKTYLNYDLVNANKQNFNNLIDEKIEQNYTGKRKIRTDAIKHIDDLITSDNDFFDNQTPEDTKQFFEYAKEFLEQEYGKDNLLYATVHMDEKTPHMHYGVVPITDDGRLSAKEVVGNKKALTAFQDRFNEHVKQRGYDLERGQSRQVTNAKHEQISQYKQKTEYHKQEYERESQKTDHIKQKNDKLMQEYQKSLNTLKKPINVPYEQETEKVGGLFSKEIQETGNVVISQKDFNEFQKQIKAAQDISEDYEYIKSGRALDDKDKEIREKDDLLNKAVERIENADDNFNQLYENAKPLKENIEIALKLLKILLKELERVLGRNTFAERVNKLTEDEPKLNGLAGNLDKKMNPELYSEQEQQQEQQKNQKRDRGMHL
>NZ_CP043847.1|WP_158171920.1|2144780_2145989_-|recombinase
MKLAWNTQKNKMSDVKGKEMEQERKGRIKNDEIDLKRTNLNFDLVEDERHLYHRVKDRVDYYKEQGSRVQKNSVVMYSNIITLSQEEADRMGETRTKHYFKTCKDYFSERFGEANVVSAKVHMDESAPHMHLHFIPVNHQGRLSARTAMNRQAINHIHDELTTHLCQQGFDVERGSTDDNKTYIQDIHEYKKKAKVLSELDQQIETKKQLLRDINDLHDEKEHLTRDIQNLKRKNHFLQEDSQQAQEDIDLYKQLRTISRDDFKKDEEKYQKEIKAYEASLSGLRMNYRDLDKRNQHLTTQNNQLEHHLDMLNARHQAMNDMVRNDTRILFAGLRCALKDRNIELSAEIKYQRMPEVGIDPDTVDQGALIHAYQGDVSGIDHHIRKASAPIKKETENDLELE
>NZ_CP043847.1|WP_002494373.1|2146443_2146896_+|hypothetical-protein
MPKKQSSKEKILTVRVSQAQYKKIQDLAYIRSMNVTEYIRQTAVGNRIKPTVIEYPKEQITMDDSNSKNNTNNLYKVIEHLEEDNEALKSDRDALRQRHDQLEDDIEQYKRENEIFHRLLEHFDSTAFMNFNTYRDDRPLKKEIKRLKEH
>NZ_CP043847.1|WP_002494371.1|2147486_2147861_-|hypothetical-protein
MKKIVYILGTIIVLGFCYFYVNLIFFDSWTRYSAEKEINNYISNHDTKKLKEISANNKTYQLLKHAKHVTIKGDTDNQGGGHIGYFTSTINGKEGALFVHLNFGLFPEIPKVTKLEVFDKNIYE
>NZ_CP043847.1|WP_021298942.1|2147975_2148650_-|IS6-family-transposase
MNYFRYKQFDKDVITVAVGYYLRYALSYRDISEILRERGVTVHHSTVYRWVQEYAPILYQIWKQKHKKAYYKWHVDETYIKIKGKWCYLYRAIDADGHTLDIWLRKQRDNHAAYAFIKRLIKQFGKPKMIITDQAPSTKIAMSKLIKDFKLNSNCHCTSKYLNNLIEQDHRHIKVRKISYQSINTAKNTIKGIECIYGLYKKNRRSLQIYGFSPCREISIMLAS
>NZ_CP043847.1|WP_017464755.1|2149216_2149804_+|hypothetical-protein
MKAYLYKFMPLLIFVIGLIIFYVFNDYPILLHVIVIIAFITNGLKNVYFVNNNIRNHMIWVSPKLDRILGMLSGILYSGIYVVGFIKQQPLWIVILILVSTMGTAVLLETKLHITSHQLEETLSSEGIKRKVISRHKAQRLKCIFFTVIVVVIISMLISLYLKLMVIFGLAVAIFIFASISVAIFEKYFTIIENM
>NZ_CP043847.1|WP_017464756.1|2150109_2151411_+|Na+/H+-antiporter-NhaC-family-protein
MKEMKNGNAWALIPLLLFVLLFLGVGIISGDFTTMPLNVAITITVIVALLMNRKETFAKKVEVFTKGAGHSNIILMMLIFILAGAFSTTAEKMGGVSSTVNLGLSLIPQNLIIVGLFIICMFVSISMGTSVGTVAAIAPVGFGFAQATDVPAALAMATVVGGAMFGDNLSMISDTTIAAVRTQKTKMSDKFKVNFKIVLPGAIITIIILFFLTNGISIDHTKNYDYNLIKVIPYLLVLILALVGINVIIVLIGGTVLAGIIGLIDGSFGWNGLLNAISKGIIGMEDIAMIALLIGGLVGIIQHNGGIDWLLNFVRSKVKSKRGAELGIASLVSAADISTANNTISIIMAGPLAKNIADEYDVDPRKSASILDIFGGCFQGLLPYSPQVISAAGVAGISPFLMLQYSIYPILLGVCGLVAIILRAPRLNKSSKK
>NZ_CP043847.1|WP_002457260.1|2151707_2152220_+|SRPBCC-domain-containing-protein
MAKYNVENEYVEIDIERLLKYTPEVVYEAWTKTDILKKWFMTTQRTNKSFDADIQEGGKYRIIDSRNGKQNIIEGTYEELVLDEYIKMTIGMPGLSEEEDVIEVEFFERENGGTQMFFYYRSFIEKERRLTTLEYKQKKKEYHDSTAHGFELMIDQMQNVIDEIEEQRHN
>NZ_CP043847.1|WP_017464758.1|2153327_2154917_+|PTS-transporter-subunit-EIIC
MNAIKRFGSAMIVPVLMFAFFGIVLGFATLFKNPTIMGGLADQHTFWFKFWSVIESGGWVIFTHMEIVFVVGLPLSLAKKAPGHAALAALMGYLMFNTFINAILTQWPHTFGANLKKGVENTTGLKSIAGIETLDTNILGAIIISGIITWIHNRYYSKRLPEMLGVFQGLTFVVTISFFVMLPVAAITCVVWPTIQHGIASIQYFIVASGYIGVWLYHFLERVLIPTGLHHFIYAPIEVGPVVVNHGLKAEWLQHLNQFAESNKPLKEQFPYGFMLQGNGKVFGCLGIALAMYATTPKENRKKVAALLIPATLTAVVAGITEPLEFTFLFIAPFLFVLHALLAATMDTLMYGFGVVGNMGGGVLDFIATNWIPLGKAHWMTYVFQVVIGLIFVAIYYFLFKYLILKFDIPLPGRKKGEEEVKLFSKQDYKDKKGESTRNHSPNSEYEEKAMYYLEGLGGKENIKDVTNCTTRLRLTVKDESKVQESAYFTHNQMSHGLVKSGKSVQVVVGMSVPQVREAFENIVNDDLS
>NZ_CP043847.1|WP_002474475.1|2155021_2155552_-|hypothetical-protein
MLIDKFETYIINVAGLKSRSTRKKLIHLCKEITFCESFQYSIIKQNDVFALEVSLPKLQLPYLISFLSFHNYAIYQILLPNRVNELLDSEQLYQSIKRFDLAIDGLQDAFIKDKVIDIMNMFANHHNVNYTLNNNCASVTCPPEIFTKLLQTIATRNIDILSASYRAKMIHKARIS
>NZ_CP043847.1|WP_059224240.1|2155853_2156489_+|HAD-IA-family-hydrolase
MYKAVVFDFDGTVIDTEKHLFDLINKHLKIHQVAPISLEFYKQFIGGEATELHKYLEDAIGFKNKEKIYDQYYQTSVELPVNPTIIQLMQYLKKRHIPMAITTSSYKKNIYPIFKQLGLDTYIDVVVGRENVDSVQPNPEIYLKAVQELNYNPTNCLAIEDSVNGATAAMLAGLDVVVNTNIITKNQDFSTVQCVGQDMEFEDIKNFLFKE

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP043847_6	6.1\|2144281\|52\|NZ_CP043847\|CRISPRCasFinder	2144281-2144332	52	NZ_CP053958	Staphylococcus capitis strain FDAARGOS_753 plasmid unnamed1	460-511	1	0.981
NZ_CP043847_6	6.1\|2144281\|52\|NZ_CP043847\|CRISPRCasFinder	2144281-2144332	52	NZ_CP053958	Staphylococcus capitis strain FDAARGOS_753 plasmid unnamed1	14579-14630	1	0.981
NZ_CP043847_6	6.1\|2144281\|52\|NZ_CP043847\|CRISPRCasFinder	2144281-2144332	52	NZ_CP023971	Staphylococcus lugdunensis strain FDAARGOS_381 plasmid unnamed1, complete sequence	6756-6807	4	0.923
NZ_CP043847_6	6.1\|2144281\|52\|NZ_CP043847\|CRISPRCasFinder	2144281-2144332	52	NZ_CP014131	Staphylococcus epidermidis strain FDAARGOS_161 plasmid unnamed2, complete sequence	4639-4690	4	0.923
NZ_CP043847_4	4.1\|1429659\|31\|NZ_CP043847\|CRISPRCasFinder	1429659-1429689	31	MN694088	Marine virus AFVG_250M454, complete genome	24345-24375	7	0.774
NZ_CP043847_4	4.1\|1429659\|31\|NZ_CP043847\|CRISPRCasFinder	1429659-1429689	31	MN694007	Marine virus AFVG_250M456, complete genome	24390-24420	7	0.774
NZ_CP043847_4	4.1\|1429659\|31\|NZ_CP043847\|CRISPRCasFinder	1429659-1429689	31	MN694027	Marine virus AFVG_250M455, complete genome	27746-27776	7	0.774
NZ_CP043847_2	2.1\|204052\|35\|NZ_CP043847\|CRISPRCasFinder	204052-204086	35	NZ_CP038614	Arsenophonus nasoniae strain FIN plasmid pArsFIN2, complete sequence	109043-109077	8	0.771
NZ_CP043847_4	4.1\|1429659\|31\|NZ_CP043847\|CRISPRCasFinder	1429659-1429689	31	NZ_CP044979	Bacillus thuringiensis strain BT62 plasmid pBT62A, complete sequence	497396-497426	8	0.742
NZ_CP043847_4	4.1\|1429659\|31\|NZ_CP043847\|CRISPRCasFinder	1429659-1429689	31	NZ_CP042875	Bacillus cereus strain 09 plasmid unnamed1, complete sequence	258656-258686	8	0.742
NZ_CP043847_4	4.1\|1429659\|31\|NZ_CP043847\|CRISPRCasFinder	1429659-1429689	31	NZ_CP011152	Bacillus cereus strain CMCC P0021 plasmid pRML04, complete sequence	236017-236047	8	0.742
NZ_CP043847_4	4.1\|1429659\|31\|NZ_CP043847\|CRISPRCasFinder	1429659-1429689	31	NZ_CP040345	Bacillus albus strain DLOU-Yingkou plasmid unnamed1, complete sequence	500601-500631	8	0.742
NZ_CP043847_4	4.1\|1429659\|31\|NZ_CP043847\|CRISPRCasFinder	1429659-1429689	31	NZ_CP045607	Bacillus cereus strain SB1 plasmid p1, complete sequence	543655-543685	8	0.742
NZ_CP043847_4	4.1\|1429659\|31\|NZ_CP043847\|CRISPRCasFinder	1429659-1429689	31	NZ_CP050184	Bacillus thuringiensis strain HER1410 plasmid pLUSID1, complete sequence	314624-314654	8	0.742
NZ_CP043847_4	4.1\|1429659\|31\|NZ_CP043847\|CRISPRCasFinder	1429659-1429689	31	NZ_CP016589	Bacillus thuringiensis strain KNU-07 plasmid pBTKNU07-01, complete sequence	124806-124836	8	0.742
NZ_CP043847_4	4.1\|1429659\|31\|NZ_CP043847\|CRISPRCasFinder	1429659-1429689	31	NZ_CP034911	Ensifer alkalisoli strain YIC4027 plasmid unnamed, complete sequence	337057-337087	8	0.742
NZ_CP043847_4	4.1\|1429659\|31\|NZ_CP043847\|CRISPRCasFinder	1429659-1429689	31	NZ_CP040783	Bacillus thuringiensis strain HM-311 plasmid p1, complete sequence	80159-80189	8	0.742
NZ_CP043847_4	4.1\|1429659\|31\|NZ_CP043847\|CRISPRCasFinder	1429659-1429689	31	NC_020394	Bacillus thuringiensis serovar thuringiensis str. IS5056 plasmid pIS56-233, complete sequence	137021-137051	8	0.742
NZ_CP043847_4	4.1\|1429659\|31\|NZ_CP043847\|CRISPRCasFinder	1429659-1429689	31	NZ_CP014283	Bacillus thuringiensis strain Bt185 plasmid pBT1850636, complete sequence	280870-280900	8	0.742
NZ_CP043847_4	4.1\|1429659\|31\|NZ_CP043847\|CRISPRCasFinder	1429659-1429689	31	NZ_CP031069	Bacillus sp. JAS24-2 plasmid pl626, complete sequence	622506-622536	8	0.742
NZ_CP043847_4	4.1\|1429659\|31\|NZ_CP043847\|CRISPRCasFinder	1429659-1429689	31	NZ_CP020005	Bacillus thuringiensis strain Bacillus thuringiensis L-7601 plasmid unnamed3, complete sequence	75068-75098	8	0.742
NZ_CP043847_4	4.1\|1429659\|31\|NZ_CP043847\|CRISPRCasFinder	1429659-1429689	31	NZ_CP022446	Bacillus cereus C1L plasmid pC1L1, complete sequence	414799-414829	8	0.742
NZ_CP043847_4	4.1\|1429659\|31\|NZ_CP043847\|CRISPRCasFinder	1429659-1429689	31	NZ_CP032614	Bacillus thuringiensis strain QZL38 plasmid p.1, complete sequence	454459-454489	8	0.742
NZ_CP043847_4	4.1\|1429659\|31\|NZ_CP043847\|CRISPRCasFinder	1429659-1429689	31	NZ_CP007513	Bacillus bombysepticus plasmid pBb, complete genome	88318-88348	8	0.742
NZ_CP043847_4	4.1\|1429659\|31\|NZ_CP043847\|CRISPRCasFinder	1429659-1429689	31	NZ_AP014865	Bacillus thuringiensis serovar tolworthi strain Pasteur Institute Standard strain plasmid pKK1, complete sequence	382031-382061	8	0.742
NZ_CP043847_4	4.1\|1429659\|31\|NZ_CP043847\|CRISPRCasFinder	1429659-1429689	31	NZ_CP053952	Bacillus cereus strain FDAARGOS_798 plasmid unnamed1, complete sequence	247116-247146	8	0.742
NZ_CP043847_4	4.1\|1429659\|31\|NZ_CP043847\|CRISPRCasFinder	1429659-1429689	31	CP046512	Bacillus cereus strain JHU plasmid p1, complete sequence	459206-459236	8	0.742
NZ_CP043847_4	4.1\|1429659\|31\|NZ_CP043847\|CRISPRCasFinder	1429659-1429689	31	NZ_CP023246	Bacillus cereus strain HBL-AI plasmid unnamed1, complete sequence	513161-513191	8	0.742
NZ_CP043847_4	4.1\|1429659\|31\|NZ_CP043847\|CRISPRCasFinder	1429659-1429689	31	NZ_CP011154	Bacillus cereus strain CMCC P0011 plasmid pRML05, complete sequence	310868-310898	8	0.742
NZ_CP043847_4	4.1\|1429659\|31\|NZ_CP043847\|CRISPRCasFinder	1429659-1429689	31	CP020755	Bacillus thuringiensis strain ATCC 10792 plasmid pLDW-16, complete sequence	374432-374462	8	0.742
NZ_CP043847_4	4.1\|1429659\|31\|NZ_CP043847\|CRISPRCasFinder	1429659-1429689	31	NZ_CP021062	Bacillus thuringiensis strain ATCC 10792 plasmid poh1, complete sequence	5344-5374	8	0.742
NZ_CP043847_4	4.1\|1429659\|31\|NZ_CP043847\|CRISPRCasFinder	1429659-1429689	31	NZ_CP053657	Bacillus cereus strain CTMA_1571 plasmid p.1, complete sequence	330728-330758	8	0.742
NZ_CP043847_4	4.1\|1429659\|31\|NZ_CP043847\|CRISPRCasFinder	1429659-1429689	31	NZ_CP053949	Bacillus cereus strain FDAARGOS_799 plasmid unnamed1, complete sequence	377266-377296	8	0.742

1. spacer 6.1|2144281|52|NZ_CP043847|CRISPRCasFinder matches to NZ_CP053958 (Staphylococcus capitis strain FDAARGOS_753 plasmid unnamed1) position: , mismatch: 1, identity: 0.981

ctataataatgattaaacgaattataacacctattatatagagaataaagag	CRISPR spacer
ctataataatgattaaacgaattataacacctattatatagagaataaagaa	Protospacer
***************************************************.

2. spacer 6.1|2144281|52|NZ_CP043847|CRISPRCasFinder matches to NZ_CP053958 (Staphylococcus capitis strain FDAARGOS_753 plasmid unnamed1) position: , mismatch: 1, identity: 0.981

ctataataatgattaaacgaattataacacctattatatagagaataaagag	CRISPR spacer
ctataataatgattaaacgaattataacacctattatatagagaataaagaa	Protospacer
***************************************************.

3. spacer 6.1|2144281|52|NZ_CP043847|CRISPRCasFinder matches to NZ_CP023971 (Staphylococcus lugdunensis strain FDAARGOS_381 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.923

ctataataatgattaaacgaattataacacctattatatagagaataaagag	CRISPR spacer
ctataataatgatcaaacgaattataacacctattatatagaggataaagca	Protospacer
*************.*****************************.****** .

4. spacer 6.1|2144281|52|NZ_CP043847|CRISPRCasFinder matches to NZ_CP014131 (Staphylococcus epidermidis strain FDAARGOS_161 plasmid unnamed2, complete sequence) position: , mismatch: 4, identity: 0.923

ctataataatgattaaacgaattataacacctattatatagagaataaagag	CRISPR spacer
ctataataatgatcaaacgaattataacacctattatatagaggataaagca	Protospacer
*************.*****************************.****** .

5. spacer 4.1|1429659|31|NZ_CP043847|CRISPRCasFinder matches to MN694088 (Marine virus AFVG_250M454, complete genome) position: , mismatch: 7, identity: 0.774

atccccaacttgctttgcttgttgaatttct	CRISPR spacer
attactaagttgctttgcttgttgaattaaa	Protospacer
**. *.** *******************

6. spacer 4.1|1429659|31|NZ_CP043847|CRISPRCasFinder matches to MN694007 (Marine virus AFVG_250M456, complete genome) position: , mismatch: 7, identity: 0.774

atccccaacttgctttgcttgttgaatttct	CRISPR spacer
attactaagttgctttgcttgttgaattaaa	Protospacer
**. *.** *******************

7. spacer 4.1|1429659|31|NZ_CP043847|CRISPRCasFinder matches to MN694027 (Marine virus AFVG_250M455, complete genome) position: , mismatch: 7, identity: 0.774

atccccaacttgctttgcttgttgaatttct	CRISPR spacer
attactaagttgctttgcttgttgaattaaa	Protospacer
**. *.** *******************

8. spacer 2.1|204052|35|NZ_CP043847|CRISPRCasFinder matches to NZ_CP038614 (Arsenophonus nasoniae strain FIN plasmid pArsFIN2, complete sequence) position: , mismatch: 8, identity: 0.771

ccaacaaagagaatttcacaaagaaat-tcaacagg	CRISPR spacer
taaacaaagagaattttccaaagaaataataacat-	Protospacer
. **************. *********  .****

9. spacer 4.1|1429659|31|NZ_CP043847|CRISPRCasFinder matches to NZ_CP044979 (Bacillus thuringiensis strain BT62 plasmid pBT62A, complete sequence) position: , mismatch: 8, identity: 0.742

atccccaacttgctttgcttgttgaatttct	CRISPR spacer
ttttcggtcttgttttgcttgttgtatttct	Protospacer
 *..* . ****.*********** ******

10. spacer 4.1|1429659|31|NZ_CP043847|CRISPRCasFinder matches to NZ_CP042875 (Bacillus cereus strain 09 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.742

atccccaacttgctttgcttgttgaatttct	CRISPR spacer
ttttcggtcttgttttgcttgttgtatttct	Protospacer
 *..* . ****.*********** ******

11. spacer 4.1|1429659|31|NZ_CP043847|CRISPRCasFinder matches to NZ_CP011152 (Bacillus cereus strain CMCC P0021 plasmid pRML04, complete sequence) position: , mismatch: 8, identity: 0.742

atccccaacttgctttgcttgttgaatttct	CRISPR spacer
ttttcggtcttgttttgcttgttgtatttct	Protospacer
 *..* . ****.*********** ******

12. spacer 4.1|1429659|31|NZ_CP043847|CRISPRCasFinder matches to NZ_CP040345 (Bacillus albus strain DLOU-Yingkou plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.742

atccccaacttgctttgcttgttgaatttct	CRISPR spacer
ttttcgctcttgttttgcttgttgtatttct	Protospacer
 *..*   ****.*********** ******

13. spacer 4.1|1429659|31|NZ_CP043847|CRISPRCasFinder matches to NZ_CP045607 (Bacillus cereus strain SB1 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.742

atccccaacttgctttgcttgttgaatttct	CRISPR spacer
ttttcggtcttgttttgcttgttgtatttct	Protospacer
 *..* . ****.*********** ******

14. spacer 4.1|1429659|31|NZ_CP043847|CRISPRCasFinder matches to NZ_CP050184 (Bacillus thuringiensis strain HER1410 plasmid pLUSID1, complete sequence) position: , mismatch: 8, identity: 0.742

atccccaacttgctttgcttgttgaatttct	CRISPR spacer
ttttcggtcttgttttgcttgttgtatttct	Protospacer
 *..* . ****.*********** ******

15. spacer 4.1|1429659|31|NZ_CP043847|CRISPRCasFinder matches to NZ_CP016589 (Bacillus thuringiensis strain KNU-07 plasmid pBTKNU07-01, complete sequence) position: , mismatch: 8, identity: 0.742

atccccaacttgctttgcttgttgaatttct	CRISPR spacer
ttttcggtcttgttttgcttgttgtatttct	Protospacer
 *..* . ****.*********** ******

16. spacer 4.1|1429659|31|NZ_CP043847|CRISPRCasFinder matches to NZ_CP034911 (Ensifer alkalisoli strain YIC4027 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

atccccaacttgctttgcttgttgaatttct	CRISPR spacer
ggcgcttgcttgctttgccttttgaatttct	Protospacer
. * *. .**********.* **********

17. spacer 4.1|1429659|31|NZ_CP043847|CRISPRCasFinder matches to NZ_CP040783 (Bacillus thuringiensis strain HM-311 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.742

atccccaacttgctttgcttgttgaatttct	CRISPR spacer
ttttcggtcttgttttgcttgttgtatttct	Protospacer
 *..* . ****.*********** ******

18. spacer 4.1|1429659|31|NZ_CP043847|CRISPRCasFinder matches to NC_020394 (Bacillus thuringiensis serovar thuringiensis str. IS5056 plasmid pIS56-233, complete sequence) position: , mismatch: 8, identity: 0.742

atccccaacttgctttgcttgttgaatttct	CRISPR spacer
ttttcggtcttgttttgcttgttgtatttct	Protospacer
 *..* . ****.*********** ******

19. spacer 4.1|1429659|31|NZ_CP043847|CRISPRCasFinder matches to NZ_CP014283 (Bacillus thuringiensis strain Bt185 plasmid pBT1850636, complete sequence) position: , mismatch: 8, identity: 0.742

atccccaacttgctttgcttgttgaatttct	CRISPR spacer
ttttcggtcttgttttgcttgttgtatttct	Protospacer
 *..* . ****.*********** ******

20. spacer 4.1|1429659|31|NZ_CP043847|CRISPRCasFinder matches to NZ_CP031069 (Bacillus sp. JAS24-2 plasmid pl626, complete sequence) position: , mismatch: 8, identity: 0.742

atccccaacttgctttgcttgttgaatttct	CRISPR spacer
gtttcggtcttgttttgcttgttgtatttct	Protospacer
.*..* . ****.*********** ******

21. spacer 4.1|1429659|31|NZ_CP043847|CRISPRCasFinder matches to NZ_CP020005 (Bacillus thuringiensis strain Bacillus thuringiensis L-7601 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.742

atccccaacttgctttgcttgttgaatttct	CRISPR spacer
ttttcggtcttgttttgcttgttgtatttct	Protospacer
 *..* . ****.*********** ******

22. spacer 4.1|1429659|31|NZ_CP043847|CRISPRCasFinder matches to NZ_CP022446 (Bacillus cereus C1L plasmid pC1L1, complete sequence) position: , mismatch: 8, identity: 0.742

atccccaacttgctttgcttgttgaatttct	CRISPR spacer
ttttcggtcttgttttgcttgttgtatttct	Protospacer
 *..* . ****.*********** ******

23. spacer 4.1|1429659|31|NZ_CP043847|CRISPRCasFinder matches to NZ_CP032614 (Bacillus thuringiensis strain QZL38 plasmid p.1, complete sequence) position: , mismatch: 8, identity: 0.742

atccccaacttgctttgcttgttgaatttct	CRISPR spacer
ttttcggtcttgttttgcttgttgtatttct	Protospacer
 *..* . ****.*********** ******

24. spacer 4.1|1429659|31|NZ_CP043847|CRISPRCasFinder matches to NZ_CP007513 (Bacillus bombysepticus plasmid pBb, complete genome) position: , mismatch: 8, identity: 0.742

atccccaacttgctttgcttgttgaatttct	CRISPR spacer
ttttcggtcttgttttgcttgttgtatttct	Protospacer
 *..* . ****.*********** ******

25. spacer 4.1|1429659|31|NZ_CP043847|CRISPRCasFinder matches to NZ_AP014865 (Bacillus thuringiensis serovar tolworthi strain Pasteur Institute Standard strain plasmid pKK1, complete sequence) position: , mismatch: 8, identity: 0.742

atccccaacttgctttgcttgttgaatttct	CRISPR spacer
ttttcggtcttgttttgcttgttgtatttct	Protospacer
 *..* . ****.*********** ******

26. spacer 4.1|1429659|31|NZ_CP043847|CRISPRCasFinder matches to NZ_CP053952 (Bacillus cereus strain FDAARGOS_798 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.742

atccccaacttgctttgcttgttgaatttct	CRISPR spacer
ttttcggtcttgttttgcttgttgtatttct	Protospacer
 *..* . ****.*********** ******

27. spacer 4.1|1429659|31|NZ_CP043847|CRISPRCasFinder matches to CP046512 (Bacillus cereus strain JHU plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.742

atccccaacttgctttgcttgttgaatttct	CRISPR spacer
ttttcggtcttgttttgcttgttgtatttct	Protospacer
 *..* . ****.*********** ******

28. spacer 4.1|1429659|31|NZ_CP043847|CRISPRCasFinder matches to NZ_CP023246 (Bacillus cereus strain HBL-AI plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.742

atccccaacttgctttgcttgttgaatttct	CRISPR spacer
ttttcggtcttgttttgcttgttgtatttct	Protospacer
 *..* . ****.*********** ******

29. spacer 4.1|1429659|31|NZ_CP043847|CRISPRCasFinder matches to NZ_CP011154 (Bacillus cereus strain CMCC P0011 plasmid pRML05, complete sequence) position: , mismatch: 8, identity: 0.742

atccccaacttgctttgcttgttgaatttct	CRISPR spacer
ttttcggtcttgttttgcttgttgtatttct	Protospacer
 *..* . ****.*********** ******

30. spacer 4.1|1429659|31|NZ_CP043847|CRISPRCasFinder matches to CP020755 (Bacillus thuringiensis strain ATCC 10792 plasmid pLDW-16, complete sequence) position: , mismatch: 8, identity: 0.742

atccccaacttgctttgcttgttgaatttct	CRISPR spacer
ttttcggtcttgttttgcttgttgtatttct	Protospacer
 *..* . ****.*********** ******

31. spacer 4.1|1429659|31|NZ_CP043847|CRISPRCasFinder matches to NZ_CP021062 (Bacillus thuringiensis strain ATCC 10792 plasmid poh1, complete sequence) position: , mismatch: 8, identity: 0.742

atccccaacttgctttgcttgttgaatttct	CRISPR spacer
ttttcggtcttgttttgcttgttgtatttct	Protospacer
 *..* . ****.*********** ******

32. spacer 4.1|1429659|31|NZ_CP043847|CRISPRCasFinder matches to NZ_CP053657 (Bacillus cereus strain CTMA_1571 plasmid p.1, complete sequence) position: , mismatch: 8, identity: 0.742

atccccaacttgctttgcttgttgaatttct	CRISPR spacer
ttttcggtcttgttttgcttgttgtatttct	Protospacer
 *..* . ****.*********** ******

33. spacer 4.1|1429659|31|NZ_CP043847|CRISPRCasFinder matches to NZ_CP053949 (Bacillus cereus strain FDAARGOS_799 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.742

atccccaacttgctttgcttgttgaatttct	CRISPR spacer
ttttcggtcttgttttgcttgttgtatttct	Protospacer
 *..* . ****.*********** ******

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

27516 : 57281

Staphylococcus_phage(81.48%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_017464587.1\|27516_27714_+	hypothetical protein	S4TZT2	uncultured_phage	3.3e-06	47.5
WP_017464586.1\|27889_29131_+	Fic family protein	Q9AZ49	Lactococcus_phage	2.4e-46	30.7
WP_158171976.1\|29637_29913_-	hypothetical protein	A0A2H4JGN1	uncultured_Caudovirales_phage	1.1e-28	68.1
WP_017464584.1\|30156_30810_-	hypothetical protein	A0A2H4J5B8	uncultured_Caudovirales_phage	1.2e-09	51.8
WP_080033120.1\|30905_31070_-	hypothetical protein	NA	NA	NA	NA
WP_158171673.1\|32057_33482_+	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	3.5e-174	64.3
WP_017464582.1\|33471_34473_+	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	5.8e-91	49.5
WP_001829824.1\|34469_34721_-	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	1.9e-35	81.9
WP_158171674.1\|34779_35256_+	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	1.3e-43	57.4
WP_017464581.1\|35242_36028_+	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	2.0e-99	71.3
WP_017464580.1\|36258_37851_-	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	7.2e-269	83.6
WP_001829830.1\|38220_39420_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	4.1e-192	85.4
WP_002476959.1\|39522_40431_+	hypothetical protein	A0A2H4PQQ8	Staphylococcus_phage	5.1e-102	80.2
WP_017464578.1\|40612_41449_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	4.5e-121	73.3
WP_017464577.1\|41700_42054_-	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	5.0e-05	33.3
WP_002476956.1\|42050_42416_-	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	1.8e-34	57.9
WP_002487559.1\|42455_42764_-	hypothetical protein	NA	NA	NA	NA
WP_002476955.1\|43040_43754_+	transaldolase	M1PR54	Cyanophage	1.6e-21	36.9
WP_059279942.1\|43893_44337_+	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	1.8e-15	47.3
WP_002498013.1\|44323_44767_-	competence protein ComK	NA	NA	NA	NA
WP_017464574.1\|44772_45252_-	sigma-70 family RNA polymerase sigma factor	A0A2H4PQT5	Staphylococcus_phage	4.1e-26	43.6
WP_002456441.1\|45458_45674_+	hypothetical protein	NA	NA	NA	NA
WP_001830727.1\|46051_46903_+	autolysin	A0A1J0MFB0	Staphylococcus_phage	1.0e-32	35.6
WP_080395238.1\|47241_48735_+	pyridine nucleotide-disulfide oxidoreductase	A0A2H4PQX2	Staphylococcus_phage	2.6e-10	57.8
WP_002440254.1\|49170_50214_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	3.4e-134	66.5
WP_002467848.1\|50220_50853_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.1e-87	77.6
WP_017464571.1\|50865_52047_+	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	1.5e-178	76.1
WP_002474722.1\|52059_52521_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	2.7e-59	83.6
WP_017464570.1\|52568_53570_-	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	2.6e-131	70.0
WP_002489440.1\|53812_54640_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_001830809.1\|55129_55531_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_017464569.1\|55767_56331_-	methyltransferase domain-containing protein	A0A2H4PQV0	Staphylococcus_phage	3.0e-68	66.5
WP_001830802.1\|56327_57281_-	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	3.3e-67	84.7

DBSCAN-SWA_2

186935 : 196525

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002476884.1\|186935_187940_+	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1
WP_080033123.1\|187902_188967_+\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_002474775.1\|188987_190127_+\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	1.7e-83	44.4
WP_001830800.1\|190142_190403_+	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	5.7e-06	44.3
WP_017464992.1\|190752_193044_+	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.6e-30	36.6
WP_017464636.1\|193714_195988_+	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	1.1e-65	29.6
WP_002476881.1\|196006_196525_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	2.8e-28	46.5

DBSCAN-SWA_3

783545 : 792015

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_017464809.1\|783545_784112_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	8.0e-29	40.0
WP_002476565.1\|784111_785143_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.6e-64	42.7
WP_002446152.1\|785135_786620_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.2e-44	31.7
WP_158171753.1\|786598_788788_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	2.5e-139	40.3
WP_059279867.1\|788780_789452_-	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
WP_001831728.1\|789453_789714_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_002474564.1\|789713_790418_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	H8ZMN3	Synechococcus_phage	1.2e-47	42.5
WP_001831674.1\|790418_791546_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_001831735.1\|791532_792015_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	5.2e-21	43.3

DBSCAN-SWA_4

823857 : 863081

uncultured_Caudovirales_phage(58.82%)

capsid,portal,holin,terminase,protease,integrase,head,tail,plate

attL 821805:821820|attR 863133:863148

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
821805:821820	attL	NA	NA	NA	NA
WP_017464465.1\|823857_824268_-\|holin	phage holin	A0A0N9SI57	Staphylococcus_phage	1.6e-58	89.0
WP_017464464.1\|824331_824730_-	YxeA family protein	A0A0N7GFH8	Staphylococcus_phage	1.4e-64	98.5
WP_002499222.1\|824887_825295_-	hypothetical protein	A0A0N9STL6	Staphylococcus_phage	3.3e-69	100.0
WP_158171757.1\|825281_825707_-	hypothetical protein	A0A0N9S016	Staphylococcus_phage	6.3e-71	97.2
WP_029376548.1\|825703_826327_-	poly-gamma-glutamate hydrolase family protein	A0A0N9SKG5	Staphylococcus_phage	1.2e-115	99.0
WP_017464460.1\|826331_827546_-\|plate	BppU family phage baseplate upper protein	A0A2H4JC27	uncultured_Caudovirales_phage	3.4e-226	99.8
WP_158171758.1\|827545_829408_-	DUF2817 domain-containing protein	A0A0N9SJ39	Staphylococcus_phage	0.0e+00	98.5
WP_158171759.1\|829589_831158_-	peptidase	A0A0N9SH60	Staphylococcus_phage	1.0e-299	98.8
WP_017464456.1\|831158_831992_-\|tail	phage tail family protein	A0A0N7GFH9	Staphylococcus_phage	1.4e-162	99.6
WP_158171760.1\|831993_836490_-	peptidoglycan DD-metalloendopeptidase family protein	A0A2H4J784	uncultured_Caudovirales_phage	0.0e+00	98.2
WP_157781582.1\|836518_836671_-	hypothetical protein	A0A0N9SKE8	Staphylococcus_phage	4.0e-20	98.0
WP_002499232.1\|836703_837066_-	hypothetical protein	A0A2H4J3V2	uncultured_Caudovirales_phage	3.3e-60	100.0
WP_002499233.1\|837129_837315_-	hypothetical protein	A0A2H4JBH1	uncultured_Caudovirales_phage	4.1e-27	100.0
WP_017464454.1\|837333_837960_-\|tail	phage tail protein	A0A2H4J976	uncultured_Caudovirales_phage	7.5e-113	99.5
WP_017464453.1\|837972_838377_-	hypothetical protein	A0A2H4JC37	uncultured_Caudovirales_phage	2.1e-71	99.3
WP_002499236.1\|838379_838667_-	hypothetical protein	A0A2H4J5J3	uncultured_Caudovirales_phage	1.1e-47	100.0
WP_002484730.1\|838780_839110_-	hypothetical protein	A0A2H4J3W3	uncultured_Caudovirales_phage	1.8e-57	99.1
WP_017464452.1\|839099_839441_-\|head,tail	phage gp6-like head-tail connector protein	A0A2H4JDD1	uncultured_Caudovirales_phage	6.0e-56	96.5
WP_059279869.1\|839459_840797_-\|capsid	phage major capsid protein	A0A2H4J3W9	uncultured_Caudovirales_phage	1.3e-167	90.7
WP_017464449.1\|840838_841396_-\|head,protease	HK97 family phage prohead protease	A0A2H4JBY8	uncultured_Caudovirales_phage	4.5e-101	98.9
WP_017464448.1\|841382_842618_-\|portal	phage portal protein	A0A2H4J5A4	uncultured_Caudovirales_phage	2.8e-228	96.3
WP_017464447.1\|842617_842812_-	hypothetical protein	A0A2H4JCL3	uncultured_Caudovirales_phage	1.0e-23	95.3
WP_017464445.1\|844567_845053_-\|terminase	phage terminase small subunit P27 family	A0A2H4J5U2	uncultured_Caudovirales_phage	1.8e-85	100.0
WP_017464444.1\|845212_845563_-	HNH endonuclease	A0A2H4J8X0	uncultured_Caudovirales_phage	2.3e-63	100.0
WP_002502054.1\|846044_846491_-	transcriptional regulator	A0A0N7GFI1	Staphylococcus_phage	2.3e-79	98.0
WP_017464442.1\|846851_847154_+	hypothetical protein	A0A2H4J741	uncultured_Caudovirales_phage	3.8e-46	100.0
WP_017464441.1\|847250_847556_-	hypothetical protein	I6SB84	Staphylococcus_virus	5.6e-45	89.1
WP_017464440.1\|847623_848334_+	hypothetical protein	U3PE05	Staphylococcus_phage	1.7e-97	73.7
WP_017464439.1\|848315_848498_-	hypothetical protein	U3PJ54	Staphylococcus_phage	2.6e-18	75.0
WP_017464438.1\|848499_848847_-	hypothetical protein	A0A2H4J469	uncultured_Caudovirales_phage	3.3e-17	70.3
WP_158171761.1\|848869_849757_-	DnaD domain protein	A0A2H4J935	uncultured_Caudovirales_phage	2.4e-112	98.3
WP_017464436.1\|849791_849989_-	helix-turn-helix transcriptional regulator	A0A2H4JC02	uncultured_Caudovirales_phage	4.0e-28	98.5
WP_017464435.1\|849985_850189_-	helix-turn-helix transcriptional regulator	A0A2H4J5F7	uncultured_Caudovirales_phage	6.8e-31	98.5
WP_017464434.1\|850203_850668_-	single-stranded DNA-binding protein	A0A2H4J3T1	uncultured_Caudovirales_phage	8.4e-69	97.4
WP_158171980.1\|850668_851286_-	MBL fold metallo-hydrolase	A0A0N9SI86	Staphylococcus_phage	1.5e-84	96.9
WP_017464432.1\|851366_852290_-	recombinase RecT	A0A0N9S045	Staphylococcus_phage	2.7e-143	100.0
WP_158171762.1\|852291_854241_-	AAA family ATPase	A0A0N9SKM4	Staphylococcus_phage	0.0e+00	98.5
WP_002499256.1\|854243_854507_-	hypothetical protein	A0A0N9RRW1	Staphylococcus_phage	7.7e-43	100.0
WP_017464430.1\|854576_854768_-	DUF1270 family protein	A0A0N9SJ68	Staphylococcus_phage	1.1e-11	71.4
WP_002502040.1\|854878_855160_+	hypothetical protein	A0A2H4JEH2	uncultured_Caudovirales_phage	2.2e-35	67.7
WP_158171763.1\|855318_855528_-	hypothetical protein	A0A0N9SHA3	Staphylococcus_phage	6.3e-32	98.6
WP_002499261.1\|855585_855924_+	hypothetical protein	A0A2H4JGF0	uncultured_Caudovirales_phage	8.3e-58	100.0
WP_002499262.1\|855909_856143_-	DUF2829 domain-containing protein	A0A0N9SKI8	Staphylococcus_phage	1.6e-39	100.0
WP_049372322.1\|856158_856914_-	Rha family transcriptional regulator	A0A2H4J8U5	uncultured_Caudovirales_phage	5.9e-136	99.6
WP_017464429.1\|856964_857519_+	hypothetical protein	A0A2H4J3U5	uncultured_Caudovirales_phage	5.1e-89	100.0
WP_017464427.1\|857678_857894_-	hypothetical protein	A0A2H4J3T8	uncultured_Caudovirales_phage	2.6e-33	100.0
WP_158171764.1\|858090_858717_+	transcriptional regulator	A0A2H4J3T7	uncultured_Caudovirales_phage	1.2e-105	95.2
WP_002500135.1\|858950_860090_+	CapA family protein	A0A2H4JG01	uncultured_Caudovirales_phage	1.2e-220	98.9
WP_002500136.1\|860298_860967_+	hypothetical protein	A0A2H4J494	uncultured_Caudovirales_phage	1.1e-64	98.2
WP_002500137.1\|861090_861612_+	hypothetical protein	A0A0H3U494	Staphylococcus_phage	2.8e-68	68.2
WP_002500138.1\|861604_861976_+	hypothetical protein	NA	NA	NA	NA
WP_002500139.1\|862031_863081_+\|integrase	site-specific integrase	A0A2H4JB53	uncultured_Caudovirales_phage	3.1e-196	98.9
863133:863148	attR	NA	NA	NA	NA

DBSCAN-SWA_5

1078420 : 1088851

uncultured_Caudovirales_phage(62.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002493501.1\|1078420_1079200_-	ATP-binding cassette domain-containing protein	W6JKT0	Anomala_cuprea_entomopoxvirus	6.7e-18	33.6
WP_017464607.1\|1079196_1080156_-	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	9.1e-17	98.0
WP_017464606.1\|1080139_1081114_-	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	4.5e-165	99.1
WP_001829597.1\|1081362_1082331_-	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	3.9e-185	100.0
WP_158171785.1\|1082449_1084555_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	99.6
WP_002473976.1\|1084517_1084916_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.0e-70	99.2
WP_002473943.1\|1085672_1086548_+	DMT family transporter	NA	NA	NA	NA
WP_001832596.1\|1086561_1087062_+	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	1.1e-50	70.1
WP_002473947.1\|1087345_1088851_+	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	5.5e-61	34.0

DBSCAN-SWA_6

2125172 : 2165022

Staphylococcus_phage(66.67%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002477120.1\|2125172_2126321_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_002477121.1\|2126568_2127504_+	formimidoylglutamase	NA	NA	NA	NA
WP_158171916.1\|2127974_2129093_+	amidohydrolase	NA	NA	NA	NA
WP_158171917.1\|2129189_2130071_+	SDR family oxidoreductase	A0A2N9QUX2	Trichoplusia_ni_ascovirus	3.4e-58	44.2
WP_021298942.1\|2130195_2130870_-\|transposase	IS6 family transposase	A0A0N9RU54	Staphylococcus_phage	2.1e-116	89.3
WP_020368409.1\|2130989_2131901_-	metallopeptidase	NA	NA	NA	NA
WP_021298942.1\|2131987_2132662_+\|transposase	IS6 family transposase	A0A0N9RU54	Staphylococcus_phage	2.1e-116	89.3
WP_000492283.1\|2133412_2134792_+	tetracycline efflux MFS transporter Tet(K)	NA	NA	NA	NA
WP_158171918.1\|2134980_2136222_+	plasmid recombination enzyme	NA	NA	NA	NA
WP_021298942.1\|2137229_2137904_+\|transposase	IS6 family transposase	A0A0N9RU54	Staphylococcus_phage	2.1e-116	89.3
WP_002494369.1\|2138877_2139264_+	hypothetical protein	NA	NA	NA	NA
WP_002494368.1\|2139423_2139873_-	hypothetical protein	NA	NA	NA	NA
WP_077431438.1\|2140048_2140237_+	hypothetical protein	NA	NA	NA	NA
WP_002494367.1\|2140484_2140880_-	DUF3139 domain-containing protein	NA	NA	NA	NA
WP_002511319.1\|2140983_2141352_+	DUF3139 domain-containing protein	NA	NA	NA	NA
WP_158171919.1\|2141481_2141847_+	hypothetical protein	NA	NA	NA	NA
WP_145356382.1\|2142713_2143325_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_145356380.1\|2143372_2144230_-	RepB family plasmid replication initiator protein	NA	NA	NA	NA
WP_158171920.1\|2144780_2145989_-	recombinase	NA	NA	NA	NA
WP_002494373.1\|2146443_2146896_+	hypothetical protein	NA	NA	NA	NA
WP_002494371.1\|2147486_2147861_-	hypothetical protein	NA	NA	NA	NA
WP_021298942.1\|2147975_2148650_-\|transposase	IS6 family transposase	A0A0N9RU54	Staphylococcus_phage	2.1e-116	89.3
WP_017464755.1\|2149216_2149804_+	hypothetical protein	NA	NA	NA	NA
WP_017464756.1\|2150109_2151411_+	Na+/H+ antiporter NhaC family protein	NA	NA	NA	NA
WP_002457260.1\|2151707_2152220_+	SRPBCC domain-containing protein	NA	NA	NA	NA
WP_017464758.1\|2153327_2154917_+	PTS transporter subunit EIIC	NA	NA	NA	NA
WP_002474475.1\|2155021_2155552_-	hypothetical protein	NA	NA	NA	NA
WP_059224240.1\|2155853_2156489_+	HAD-IA family hydrolase	A7J6N1	Paramecium_bursaria_Chlorella_virus	1.6e-09	27.7
WP_002438441.1\|2156506_2156695_+	hypothetical protein	NA	NA	NA	NA
WP_001830056.1\|2157013_2157199_-	hypothetical protein	NA	NA	NA	NA
WP_017464759.1\|2157195_2157552_-	hypothetical protein	NA	NA	NA	NA
WP_002474431.1\|2157950_2159327_+	amino acid permease	NA	NA	NA	NA
WP_002498836.1\|2159449_2160322_-	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
WP_017464760.1\|2160335_2161760_-	PTS transporter subunit EIIC	NA	NA	NA	NA
WP_002438451.1\|2161772_2162660_-	N-acetylmuramic acid 6-phosphate etherase	NA	NA	NA	NA
WP_059279760.1\|2162656_2163709_-	DUF871 domain-containing protein	NA	NA	NA	NA
WP_080033104.1\|2163888_2164236_-	hypothetical protein	NA	NA	NA	NA
WP_017464762.1\|2164275_2165022_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP043847

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CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection