CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP039266	Lactobacillus crispatus strain DC21.1 chromosome, complete genome	5 crisprs	c2c9_V-U4,cas2,cas3,DEDDh,DinG,cas14j,csa3,Cas14u_CAS-V	0	36	8	0
NZ_CP039267	Lactobacillus crispatus strain DC21.1 plasmid pLcDC21.1_1, complete sequence	0 crisprs	NA	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP039266_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP039266_1

1184365-1185248

TypeV

I-B,III-A,III-B

Consensus_repeat	Method
GGATCACCTCCACACACGTGGAGAATAC	CRISPRCasFinder
GGATCACCTCCACACACGTGGAGAATAC	CRT
GGATCACCTCCACACACGTGGAGAATAC	PILER-CR

14 spacers

cas14j

The CRISPR arrays of NZ_CP039266_1

>merge|NZ_CP039266|1|1184365-1185248|CRISPRCasFinder,CRT,PILER-CR
GCAATACCTCCACATACGTGGAGAATACTGGGTGTAACTGCTTCACTATGTTTTGTGATGGGGATCACCTCCACACACGTGGAGAATAAAACAATCAGTAATTAGCCAGCTTGATGATATTAGGATCACCTCCACACACGTGGAGAATACCAAGGAACTATGATTTTACAGACATCAGTAATGGGATCACCTCCACACACGTGGAGAATACAGCGACCAGAAATTTTTGGGTGGCTTCTTTTTAGGATCACCTCCACACACGTGGAGAATACTGCAAACGAGTTGAGAAAGTTGAAGTCCATTCGGGATCACCTCCACACACGTGGAGAATACAGACCCGAATAATTCATGATGTCCGGAAAATCAGGATCACCTCCACACACGTGGAGAATACATTCAGACAATAAGCGCCCGGCTAGATCGTCTGGGATCACCTCCACACACGTGGAGAATACTTAATGGTAATCACGTAATCACCGAAGCAAATAGGATCACCTCCACACACGTGGAGAATACCAAGTTTTGATTTTACTAGTTCTTATCCTACTGGGATCACCTCCACACACGTGGAGAATACCCTTTTAAGTGGAAGCAATCCGAGATAAATTTTAGGATCACCTCCACACACGTGGAGAATACCACGTTGATGCTATCAATTGTAGTGCCGCCGTAGGATCACCTCCACACACGTGGAGAATACGATAATTTAGGCAATCAGCAGGTAATCGTGGATAGGATCACCTCCACACACGTGGAGAATACAATAGAATTCAGAGATAGTTTAATTTTAAGTGGGGATCACCTCCACACACGTGGAGAATACAATACACTTGGTGCAGAACCTTGGTAAACTCTAGGATCACCTCCACACACGTGGAGAATAC

>NZ_CP039266|1|1|1184365-1185248|CRISPRCasFinder
GCAATACCTCCACATACGTGGAGAATAC	TGGGTGTAACTGCTTCACTATGTTTTGTGATGG
GGATCACCTCCACACACGTGGAGAATAA	AACAATCAGTAATTAGCCAGCTTGATGATATTA
GGATCACCTCCACACACGTGGAGAATAC	CAAGGAACTATGATTTTACAGACATCAGTAATG
GGATCACCTCCACACACGTGGAGAATAC	AGCGACCAGAAATTTTTGGGTGGCTTCTTTTTA
GGATCACCTCCACACACGTGGAGAATAC	TGCAAACGAGTTGAGAAAGTTGAAGTCCATTCG
GGATCACCTCCACACACGTGGAGAATAC	AGACCCGAATAATTCATGATGTCCGGAAAATCA
GGATCACCTCCACACACGTGGAGAATAC	ATTCAGACAATAAGCGCCCGGCTAGATCGTCTG
GGATCACCTCCACACACGTGGAGAATAC	TTAATGGTAATCACGTAATCACCGAAGCAAATA
GGATCACCTCCACACACGTGGAGAATAC	CAAGTTTTGATTTTACTAGTTCTTATCCTACTG
GGATCACCTCCACACACGTGGAGAATAC	CCTTTTAAGTGGAAGCAATCCGAGATAAATTTTA
GGATCACCTCCACACACGTGGAGAATAC	CACGTTGATGCTATCAATTGTAGTGCCGCCGTA
GGATCACCTCCACACACGTGGAGAATAC	GATAATTTAGGCAATCAGCAGGTAATCGTGGATA
GGATCACCTCCACACACGTGGAGAATAC	AATAGAATTCAGAGATAGTTTAATTTTAAGTGG
GGATCACCTCCACACACGTGGAGAATAC	AATACACTTGGTGCAGAACCTTGGTAAACTCTA
GGATCACCTCCACACACGTGGAGAATAC

>NZ_CP039266|1|1|1184365-1185248|CRT
GCAATACCTCCACATACGTGGAGAATAC	TGGGTGTAACTGCTTCACTATGTTTTGTGATGG
GGATCACCTCCACACACGTGGAGAATAA	AACAATCAGTAATTAGCCAGCTTGATGATATTA
GGATCACCTCCACACACGTGGAGAATAC	CAAGGAACTATGATTTTACAGACATCAGTAATG
GGATCACCTCCACACACGTGGAGAATAC	AGCGACCAGAAATTTTTGGGTGGCTTCTTTTTA
GGATCACCTCCACACACGTGGAGAATAC	TGCAAACGAGTTGAGAAAGTTGAAGTCCATTCG
GGATCACCTCCACACACGTGGAGAATAC	AGACCCGAATAATTCATGATGTCCGGAAAATCA
GGATCACCTCCACACACGTGGAGAATAC	ATTCAGACAATAAGCGCCCGGCTAGATCGTCTG
GGATCACCTCCACACACGTGGAGAATAC	TTAATGGTAATCACGTAATCACCGAAGCAAATA
GGATCACCTCCACACACGTGGAGAATAC	CAAGTTTTGATTTTACTAGTTCTTATCCTACTG
GGATCACCTCCACACACGTGGAGAATAC	CCTTTTAAGTGGAAGCAATCCGAGATAAATTTTA
GGATCACCTCCACACACGTGGAGAATAC	CACGTTGATGCTATCAATTGTAGTGCCGCCGTA
GGATCACCTCCACACACGTGGAGAATAC	GATAATTTAGGCAATCAGCAGGTAATCGTGGATA
GGATCACCTCCACACACGTGGAGAATAC	AATAGAATTCAGAGATAGTTTAATTTTAAGTGG
GGATCACCTCCACACACGTGGAGAATAC	AATACACTTGGTGCAGAACCTTGGTAAACTCTA
GGATCACCTCCACACACGTGGAGAATAC

>NZ_CP039266|1|1|1184426-1185248|PILER-CR
GGATCACCTCCACACACGTGGAGAATAA	AACAATCAGTAATTAGCCAGCTTGATGATATTA
GGATCACCTCCACACACGTGGAGAATAC	CAAGGAACTATGATTTTACAGACATCAGTAATG
GGATCACCTCCACACACGTGGAGAATAC	AGCGACCAGAAATTTTTGGGTGGCTTCTTTTTA
GGATCACCTCCACACACGTGGAGAATAC	TGCAAACGAGTTGAGAAAGTTGAAGTCCATTCG
GGATCACCTCCACACACGTGGAGAATAC	AGACCCGAATAATTCATGATGTCCGGAAAATCA
GGATCACCTCCACACACGTGGAGAATAC	ATTCAGACAATAAGCGCCCGGCTAGATCGTCTG
GGATCACCTCCACACACGTGGAGAATAC	TTAATGGTAATCACGTAATCACCGAAGCAAATA
GGATCACCTCCACACACGTGGAGAATAC	CAAGTTTTGATTTTACTAGTTCTTATCCTACTG
GGATCACCTCCACACACGTGGAGAATAC	CCTTTTAAGTGGAAGCAATCCGAGATAAATTTTA
GGATCACCTCCACACACGTGGAGAATAC	CACGTTGATGCTATCAATTGTAGTGCCGCCGTA
GGATCACCTCCACACACGTGGAGAATAC	GATAATTTAGGCAATCAGCAGGTAATCGTGGATA
GGATCACCTCCACACACGTGGAGAATAC	AATAGAATTCAGAGATAGTTTAATTTTAAGTGG
GGATCACCTCCACACACGTGGAGAATAC	AATACACTTGGTGCAGAACCTTGGTAAACTCTA
GGATCACCTCCACACACGTGGAGAATAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP039266.1\|WP_158181918.1\|1178003_1180067_-\|glycine--tRNA-ligase-subunit-beta	unknown	unknown	gnl\|CDD\|234925
NZ_CP039266.1\|WP_013086426.1\|1176153_1177974_-\|DNA-primase	unknown	unknown	gnl\|CDD\|235551
NZ_CP039266.1\|WP_158181921.1\|1189790_1190603_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376574
NZ_CP039266.1\|WP_005719721.1\|1180059_1180977_-\|glycine--tRNA-ligase-subunit-alpha	unknown	unknown	gnl\|CDD\|236473
NZ_CP039266.1\|WP_005719714.1\|1173864_1174305_+\|8-oxo-dGTP-diphosphatase	unknown	unknown	gnl\|CDD\|239519
NZ_CP039266.1\|WP_158181922.1\|1191074_1191821_-\|23S-rRNA-(adenine(2058)-N(6))-methyltransferase-Erm(B)	unknown	unknown	gnl\|CDD\|366074
NZ_CP039266.1\|WP_089143288.1\|1182227_1183529_-\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	cas14j	-	gnl\|CDD\|223747
NZ_CP039266.1\|WP_057726804.1\|1173080_1173764_-\|SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|378972
NZ_CP039266.1\|WP_158181920.1\|1188853_1189690_+\|pyruvate,-phosphate-dikinase/phosphoenolpyruvate-synthase-regulator	unknown	unknown	gnl\|CDD\|377080
NZ_CP039266.1\|WP_005719716.1\|1175025_1176138_-\|RNA-polymerase-sigma-factor-RpoD	unknown	unknown	gnl\|CDD\|236413
NZ_CP039266.1\|WP_005719727.1\|1186333_1186858_-\|rRNA-maturation-RNase-YbeY	unknown	unknown	gnl\|CDD\|376735
NZ_CP039266.1\|WP_013086431.1\|1187845_1188289_-\|GatB/YqeY-domain-containing-protein	unknown	unknown	gnl\|CDD\|370480
NZ_CP039266.1\|WP_068813836.1\|1174304_1174979_+\|M23-family-metallopeptidase	unknown	unknown	gnl\|CDD\|366703
NZ_CP039266.1\|WP_005719725.1\|1185431_1186334_-\|GTPase-Era	unknown	unknown	gnl\|CDD\|234624
NZ_CP039266.1\|WP_131501341.1\|1183802_1183895_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039266.1\|WP_158181919.1\|1181236_1181992_-\|DNA-repair-protein-RecO	unknown	unknown	gnl\|CDD\|273175
NZ_CP039266.1\|WP_158181923.1\|1192077_1192317_-\|peptide-binding-protein	unknown	unknown	gnl\|CDD\|311623
NZ_CP039266.1\|WP_002880182.1\|1188449_1188626_-\|30S-ribosomal-protein-S21	unknown	unknown	gnl\|CDD\|234707
NZ_CP039266.1\|WP_005723097.1\|1186860_1187820_-\|PhoH-family-protein	unknown	unknown	gnl\|CDD\|376820
NZ_CP039266.1\|WP_001814874.1\|1191945_1192029_-\|23S-rRNA-methyltransferase-attenuation-leader-peptide	unknown	unknown	gnl\|CDD\|368836

Protein	Function_ID	Function_description	E-value
NZ_CP039266.1\|WP_158181918.1\|1178003_1180067_-\|glycine--tRNA-ligase-subunit-beta	gnl\|CDD\|234925	PRK01233, glyS, glycyl-tRNA synthetase subunit beta; Validated.	0
NZ_CP039266.1\|WP_013086426.1\|1176153_1177974_-\|DNA-primase	gnl\|CDD\|235551	PRK05667, dnaG, DNA primase; Validated.	0
NZ_CP039266.1\|WP_158181921.1\|1189790_1190603_+\|hypothetical-protein	gnl\|CDD\|376574	pfam01610, DDE_Tnp_ISL3, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS1165.	3.22611e-26
NZ_CP039266.1\|WP_005719721.1\|1180059_1180977_-\|glycine--tRNA-ligase-subunit-alpha	gnl\|CDD\|236473	PRK09348, glyQ, glycyl-tRNA synthetase subunit alpha; Validated.	0
NZ_CP039266.1\|WP_002880182.1\|1188449_1188626_-\|30S-ribosomal-protein-S21	gnl\|CDD\|234707	PRK00270, rpsU, 30S ribosomal protein S21; Reviewed.	8.84619e-15
NZ_CP039266.1\|WP_158181922.1\|1191074_1191821_-\|23S-rRNA-(adenine(2058)-N(6))-methyltransferase-Erm(B)	gnl\|CDD\|366074	pfam00398, RrnaAD, Ribosomal RNA adenine dimethylase.	7.0568e-86
NZ_CP039266.1\|WP_089143288.1\|1182227_1183529_-\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl\|CDD\|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.66723e-30
NZ_CP039266.1\|WP_057726804.1\|1173080_1173764_-\|SAM-dependent-methyltransferase	gnl\|CDD\|378972	pfam12847, Methyltransf_18, Methyltransferase domain. Protein in this family function as methyltransferases.	1.17158e-70
NZ_CP039266.1\|WP_158181920.1\|1188853_1189690_+\|pyruvate,-phosphate-dikinase/phosphoenolpyruvate-synthase-regulator	gnl\|CDD\|377080	pfam03618, Kinase-PPPase, Kinase/pyrophosphorylase. This family of regulatory proteins has ADP-dependent kinase and inorganic phosphate-dependent pyrophosphorylase activity.	7.43813e-136
NZ_CP039266.1\|WP_005719716.1\|1175025_1176138_-\|RNA-polymerase-sigma-factor-RpoD	gnl\|CDD\|236413	PRK09210, PRK09210, RNA polymerase sigma factor RpoD; Validated.	0
NZ_CP039266.1\|WP_005719727.1\|1186333_1186858_-\|rRNA-maturation-RNase-YbeY	gnl\|CDD\|376735	pfam02130, UPF0054, Uncharacterized protein family UPF0054.	7.92136e-49
NZ_CP039266.1\|WP_013086431.1\|1187845_1188289_-\|GatB/YqeY-domain-containing-protein	gnl\|CDD\|370480	pfam09424, YqeY, Yqey-like protein. The function of this domain found in the YqeY protein is uncertain.	3.06283e-55
NZ_CP039266.1\|WP_068813836.1\|1174304_1174979_+\|M23-family-metallopeptidase	gnl\|CDD\|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	2.82111e-14
NZ_CP039266.1\|WP_005719725.1\|1185431_1186334_-\|GTPase-Era	gnl\|CDD\|234624	PRK00089, era, GTPase Era; Reviewed.	7.42691e-173
NZ_CP039266.1\|WP_158181923.1\|1192077_1192317_-\|peptide-binding-protein	gnl\|CDD\|311623	pfam07764, Omega_Repress, Omega Transcriptional Repressor. The omega transcriptional repressor regulates expression of involved in copy number control and stable maintenance of plasmids. The omega protein belongs to the structural superfamily of MetJ/Arc repressors featuring a ribbon-helix-helix DNA-binding motif with the beta-ribbon located in and recognising the major groove of operator DNA.	1.46936e-34
NZ_CP039266.1\|WP_005719714.1\|1173864_1174305_+\|8-oxo-dGTP-diphosphatase	gnl\|CDD\|239519	cd03427, MTH1, MutT homolog-1 (MTH1) is a member of the Nudix hydrolase superfamily. MTH1, the mammalian counterpart of MutT, hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP and 2-hydroxy-ATP, to monophosphates, thereby preventing the incorporation of such oxygen radicals during replication. This is an important step in the repair mechanism in genomic and mitochondrial DNA. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for activity, and contain the Nudix motif, a highly conserved 23-residue block (GX5EX7REUXEEXGU, where U = I, L or V), that functions as a metal binding and catalytic site. MTH1 is predominantly localized in the cytoplasm and mitochondria. Structurally, this enzyme adopts a similar fold to MutT despite low sequence similarity outside the conserved nudix motif. The most distinctive structural difference between MutT and MTH1 is the presence of a beta-hairpin, which is absent in MutT. This results in a much deeper and narrower substrate binding pocket. Mechanistically, MTH1 contains dual specificity for nucleotides that contain 2-OH-adenine bases and those that contain 8-oxo-guanine bases.	3.2514e-48
NZ_CP039266.1\|WP_005723097.1\|1186860_1187820_-\|PhoH-family-protein	gnl\|CDD\|376820	pfam02562, PhoH, PhoH-like protein. PhoH is a cytoplasmic protein and predicted ATPase that is induced by phosphate starvation.	6.30441e-136
NZ_CP039266.1\|WP_158181919.1\|1181236_1181992_-\|DNA-repair-protein-RecO	gnl\|CDD\|273175	TIGR00613, DNA_repair_protein_RecO, DNA repair protein RecO. All proteins in this family for which functions are known are DNA binding proteins that are involved in the initiation of recombination or recombinational repair. [DNA metabolism, DNA replication, recombination, and repair].	2.11824e-50
NZ_CP039266.1\|WP_001814874.1\|1191945_1192029_-\|23S-rRNA-methyltransferase-attenuation-leader-peptide	gnl\|CDD\|368836	pfam06308, ErmC, 23S rRNA methylase leader peptide (ErmC). This family consists of several very short bacterial 23S rRNA methylase leader peptide (ErmC) sequences. ermC confers resistance to macrolide-lincosamide streptogramin B antibiotics by specifying a ribosomal RNA methylase, which results in decreased ribosomal affinity for these antibiotics. ermC expression is induced by exposure to erythromycin.	0.00200655

>NZ_CP039266.1|WP_131501341.1|1183802_1183895_-|hypothetical-protein
MVQILWTHKKLRKFGKQWVKAWKLLQVLKI
>NZ_CP039266.1|WP_089143288.1|1182227_1183529_-|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MKRMSSLAYHFGVKLRFYPSSKQKKIIKLNYDAQRFVYNSYVGRNRSNYHAKHYLAVRQCQAMPFAFSILNNYETRLAEEVVTNSELLDKPRNIRDTYSFLRVKEIDSLAIANAIQNYQKAWNNYRKIGHGIPTFHKKRSDWSYQTNCQYPKQPEAFLDNGTARFIDAKHIKLPKLGIVRIAGFRKLIKERLLNHIPTRIGTVTIKKTADEQFYLSMQLGSDTAFIKELPKTQSQIGIDLNLDNFLTGSNGTMVANPRFYRKAEKKLAHAQRILSRRQRRAKKDGRNLRTAKNYQKQRLSVARLHDKIRRQRNEFLQVLSTALIKNHDLVVAEELRSRNLLKNHALSQAISDVGWRSFLNMLAYKAKLYGKEFLTIDPKYTTQRCHQCGSIMGQNGYKKLTLKDREWTCPICRTHHIRDWNAAVNILEKGLGK
>NZ_CP039266.1|WP_158181919.1|1181236_1181992_-|DNA-repair-protein-RecO
MARELKEVQGIIFKRQKYKEADLLAKIMTKQDGIMTLIVKGALRPKSRLSAATLNFSIGTYVIYTSGKGLSNLRTYKEAKQFDGLYRDLTRNAYISFIFDLIDHAFVEYQPIGKYYDLALFALKKIDSGVDAEMITQIVQMKMLAAYGVEPQLKHCVICGKEKGVFDYSIKMGGVICSDHFSTVTSRMHLKPKETAVIRTIGLLPIERLGDIKINEEIKRATRKAIDRIYHETIGLNLKTKKFLDELKLFS
>NZ_CP039266.1|WP_005719721.1|1180059_1180977_-|glycine--tRNA-ligase-subunit-alpha
MADKKLNIQNMIFKLEQFWSSKGCMIMPSYDVEKGAGTMSPYTFLRAVGPEPWAACYVEPSRRPADGRYGENPNRLFQHHQFQVVIKPAPKDIQQYYLDSLKVLGIDPLEHDIRFVEDNWANPSMGCAGVGWEVWLDGMEVSQFTYFQVVGELDVKPTMSEITYGVERLASYIQDVNSVFDLEWGNGILYRDIFKQPEYEHSKYAFEESNQEQLLQFFDIYEATAKRLLDKNLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNLAHEVAVKFVEEREKRGFPLLKSAEDKKAGVENG
>NZ_CP039266.1|WP_158181918.1|1178003_1180067_-|glycine--tRNA-ligase-subunit-beta
MAKDYLFEIGTEEMPAHVVPRSVKQLADRTRKFLKENGLKFKDIKTFSTPRRLTILVEDLAEKQDDIDEVKKGPAKKIAQDQDGNWTKAAQGFARGQGMTTDDIYFEELKGTEYAYVHVQKEGKKASDILLGMSDIIKAMTFPTKMRWDSNDFEFVRPIHWLVSLFGSDVIPVKILDITAGRKTQGHRFLGDSVVLANADDYGDALKDQFVIADADERKDMIVRQMNELVKKNNWQVKPDRDLLEEVTYLVEYPTVFAGSFDEKYLKIPDEVLITSMKDNQRYFEVYDENGKLINHFIAVRNGNKDYLDNVISGNEKVLVARLDDAQFFYDEDRKYPLSHFVDRLKNVSFHDKIGSMAEKMQRVRMIGDYLAKRWDLPENVVKDFDRASELYKFDLVTQMVGEFAELQGVMGMHYARLAGEDEEVSVAIKEHYMPATAEGPLPETTVGSLLSIADKIDTIVTFFGAGMIPTSSNDPYALRRYAYGIVRILLNEKWSLPFNEVLPEIISMLNGVTPAKLPKSDADQEIADFIRDRVKQYLQKNDFKYDIIDAVLASSQQDPSQILAAATVLQLHHDDEEFKPVVESLTRIDNILKKAKFKSNTAVDESLFDDNSEKELYAGVQNLQDIESLADLYQGFVQLQPVIDQYFETNMIMAKDEKVKNNRLAQLYAVNELADRLGDLSKLVIK
>NZ_CP039266.1|WP_013086426.1|1176153_1177974_-|DNA-primase
MAGRIPEDFISEVRSNVNIVDVISQYVSLEKKGKDYIGLCPFHQEKTPSFTVNADKQFFKCFGCGKGGNVFKFLMYKDDLTFPESVERVAEFAHIAMPNGYGHNSGTKLNPLMQMHQDAVDFYHRVLLTTKAGERGMQYAQKRELDQEILDHFKIGYAPKADNVLITYLRSKGYQDDDLAQSGLFVQARDGQLYDRFRDRLMFPLDNENGRTIGFSGRRISDDKTEAKYMNSPETEIFTKSKVLFHFAEAKKAARGEGHLVLYEGYMDVIAAYKAGVKSGIASMGTSLTDDQIYLLRRITPNIIINYDGDDPGVHAEERAARMFNKDGNFNLGIVVLPEKLDPDEYVKKYGAEKYLEEVKGALTPTDFFLKRLEQKYNLDNDREKIAYLGEAVKEIAQVRNPVEQDMYTEKLAKSSGVSIASLKANLAKERRRNNRARNHVRNSQRNSPDYPIDVPLPGDEDVPTEQSVVEKNPSQTRLLYLFIHSTDAQKYMLEGQFHFPNQDFETLAQDWLKYAETHENPQIDGFLDFIPEQLQGIIVDAEMAQMPKDSTIQEVDALVLALKRRNIYSRLNELQAQLQDAKRKNDAQGIIAITQEIIGLKRILG
>NZ_CP039266.1|WP_005719716.1|1175025_1176138_-|RNA-polymerase-sigma-factor-RpoD
MAEKETTQKLSLDKMVKQVVKDVKKDKSITEEDFTARLIKPYNLQGKAVDQLVQEFEDNGISIVDENGDPSKLALKKQKDVEKAELKDMSAPSSVRMNDPVRMYLKEIGRVPLLTADQEIALAKRIESGDEEAKQELAEANLRLVVSIAKRYVGRGMSFLDLIQEGNMGLMKAVDKFDYRLGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINKLIRIQRQLLQDLGREPTPEEIGAEMNMPTNKVRDILKIAQEPVSLETPIGEEDDSHLGDFIEDKDATSPEQHASYEMLKEQLEQVLETLTDREENVLRLRFGLDDGRTRTLEEVGKVFGVTRERIRQIEAKALRKLRHPSRSNQLRDFMD
>NZ_CP039266.1|WP_068813836.1|1174304_1174979_+|M23-family-metallopeptidase
MKKTESKFALLAALIAILAFASIPLWQNNLNSLRPQTHTVKKKKTAKKKKVVHVTWGYPFKKLYEKKIKFKSGQKFGETDVIRRVYPSKSYFHDGYDFGFSEVGHSPVYAVHAGTVHRVKYAPGLGLYIWIISDDGYVEVYQEGFLSITDIYVKKGQKVKLGQKIGKLTGSHIHLGVTKTDKDYIDKKHDNTPCKYYWKDNGTWLNPMKIIEDNLRAAGKDPVQ
>NZ_CP039266.1|WP_005719714.1|1173864_1174305_+|8-oxo-dGTP-diphosphatase
MSRTENVTLTNMCMVKNKDQVLVLDRNDPVWPGLTFPGGHVEAHESFHDSVVREVKEETGLTISHPQLVGVKQFYDHNDERYLVFFYIAEQFSGTVKESDEGKLTWMSAKELKKQKLAYNFDHDLPVFFEQTISEHMLDGKRDELF
>NZ_CP039266.1|WP_057726804.1|1173080_1173764_-|SAM-dependent-methyltransferase
MNLRLNTLAKMVDPGSRVADIGTDHAYLPIELVKNGKIDYAIASDVAEGPLENAKNDIAAAGLTEQIETRLGSGLETVTHADQIDTVVIAGMGGKLMTDILDRAWSKDAQFKTLVLEPNIGEAGVRNWLMMHNYKIISEKLIAEAGHTYELIKASLTEEKHEMTEKEIFFGPFIVQEKNPVFYQKWEGQLAYYQRLLVNLNKARKKDEDRINEVDHDIKLIKEELEK
>NZ_CP039266.1|WP_005719725.1|1185431_1186334_-|GTPase-Era
MEEKEFKSGFVALVGRPNVGKSTLMNYLVGQKVAITSNKPQTTRNRISGIYTSDEMQVVFVDTPGIFKPHSKLDDYMDKASVSSLNDVDLVLFMVEPEEMGKGDQYIANLLKEVKVPVLLVINKVDEIHPNKLLPIMDSYHKLEGFKEILPISATQGIGIEDLLKTIKEYLPVGPQYYGADQITDRPEYFVVAELIREQILRLTSQEVPHATAVAVDHMNTHQNGKLLIEATIYVEKDGQKGIIIGKGGKMLKQIGINSRQEIERLLGEKVNLRLWVKVQHNWRSDPNFLKRIGYDKKEL
>NZ_CP039266.1|WP_005719727.1|1186333_1186858_-|rRNA-maturation-RNase-YbeY
MDPIDITYNDEVGFLDDEKRNWQDWIMKLLLLAKKEIGKDNNLEMSINFVDEDRSHEINLKYRDKDRPTDVISFAIEDGEDSIDLAAFADDPDFQEDIGDLFMCPSVIKRHSKEYGTGFDREFGYTIVHGFLHLNGYDHIKPDEAKEMFGIQGKVLEDYGLPLYPDQLDEGRGK
>NZ_CP039266.1|WP_005723097.1|1186860_1187820_-|PhoH-family-protein
MAQTTFTPQRPENIQKLVGVNDGNLKLLSEGYDLSVSDVGNEIVIAGDDEEKIKKVVAVLKALDSVVNTGVNIGAPDTVSAMKMADKGTTEYFADLYKKVLIRDAKGRPIRVKNMGQKRYVEAIDKSDVVFGIGPAGTGKTFLAVVCAIAAFKKGEVSRIILTRPAVEAGESLGFLPGDLKEKVDPYLRPIYDSLYAILGTNTTDRLMERGVIEVAPLAYMRGRTLDDAFVILDEAQNTTDAQMKMFLTRLGFNSKMVVNGDMTQVDLPGRQHSGLIDARHILKNIDQIKFINFSANDVVRHPVVAKIITAYEKEDIKH
>NZ_CP039266.1|WP_013086431.1|1187845_1188289_-|GatB/YqeY-domain-containing-protein
MSLSDQIMADMKSAMKNHDKTTLNTVRMIKSALMNEKIKAGHDLTPDEELTVLNREKKQREESIDEFIKANRDDLAEETKKELAVVEKYMPKQMNQDELRAAVKETIDEVGAKGKSDFGKVMKALMPKIKGRADGKAASQAVRDQLN
>NZ_CP039266.1|WP_002880182.1|1188449_1188626_-|30S-ribosomal-protein-S21
MAKTIVHENESIDDALRRFKRSVSRSGTLQEYRKREFYEKPSVRRKLKSEAARKRRHY
>NZ_CP039266.1|WP_158181920.1|1188853_1189690_+|pyruvate,-phosphate-dikinase/phosphoenolpyruvate-synthase-regulator
MVETKDQNELNIIIISDAAGDTAFSNATAAAAEFPNCNINYRRYPFITNQKKLDEVLTEIEKYPNLVIIYSLVKDEMQMPVIKFAREHNVECVDIFSPVVEAIQQTTHMTPDQKIGAQHSLNQKYFDRISAMEFAVMYDDGKDPKGFLEADVVLLGVSRTSKTPLSLFLANKNLKVANLPLVPETHIPKEIYEINPKKIIGLTNDPSVLNEIRRQRMIAYGLNPDTTYSNMDSINKELESAQALYKKLGCYVINVAHRSIEETAALILEHLGIDDYAK
>NZ_CP039266.1|WP_158181921.1|1189790_1190603_+|hypothetical-protein
MSSLNESIKFYLNIEDPNIIFSDYFKKWINGKYHNLYLAELIQPYCPYYHSSNLKQNGHYTSKRKILAALTEDRSMTGIASIDRFHMVQMLTRSFNIFRVQIMKQFNKSSREYRLLKSPWILYLMKYDKLNKTTPYYDWHFKDCLTQEHVVLDGLDCDQTLENTYWVMQDFMTAIQDNDEKKVIHLLHSKQSVGKQMHQTLLTFKRNYSGVLNGITSTYSNGCLEGVNRKIKQIERTAYGYRNFKHLLIRIRLEENIIKEKESNSYFLAA
>NZ_CP039266.1|WP_158181922.1|1191074_1191821_-|23S-rRNA-(adenine(2058)-N(6))-methyltransferase-Erm(B)
MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLTTKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIPYNLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAECFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHAKVNNLSTITYEQVLSIFNSYLLFNGRKLIL
>NZ_CP039266.1|WP_001814874.1|1191945_1192029_-|23S-rRNA-methyltransferase-attenuation-leader-peptide
MLVFQMRNVDKTSTVLKQTKNSDYADK
>NZ_CP039266.1|WP_158181923.1|1192077_1192317_-|peptide-binding-protein
MIVGNLGAQKEKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAKNGGNVKEVMEIRLRSKLKRVLIVHYLKILYNRN

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Crispr_ID: NZ_CP039266_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP039266_2

1207296-1208177

Orphan

I-B,III-A,III-B

Consensus_repeat	Method
GGATCACCTCCACATGTGTGGAGAATAC	CRISPRCasFinder
GGATCACCTCCACATGTGTGGAGAATAC	CRT
GGATCACCTCCACATGTGTGGAGAATAC	PILER-CR

14 spacers

The CRISPR arrays of NZ_CP039266_2

>merge|NZ_CP039266|2|1207296-1208177|CRISPRCasFinder,CRT,PILER-CR
TAACACTCTCAACATGTGTGGAGAATACCTTCGGCACCCTCAGCGAAATTAGACGGTATAAGGATCACCTCCACATGTGTGGAGAATACCATACTTATAAAATCTCCAAGGTTGATAACAGAGGATCACCTCCACATGTGTGGAGAATACACAAAAGTTAAAAGCCGTTCAAGTGTTCACTTAGGATCACCTCCACATGTGTGGAGAATACACACTAAGAAAGTACCTGGTAATGTTTGGAATAGGATCACCTCCACATGTGTGGAGAATACTAGTATCTGAATCAACCGTGCCGTTAACGGTGAGGATCACCTCCACATGTGTGGAGAATACATGACACAACATCTTTTAAAGGTTCAAGAAGTAGGATCACCTCCACATGTGTGGAGAATACCAAGTGGTGTTGTGTCTGCGATGTCTCCACCAAGGATCACCTCCACATGTGTGGAGAATACATTTAGATTTAAACCGTTATACTGGTTCAATCGGGATCACCTCCACATGTGTGGAGAATACCTCATATCTAGTTTACGATTATCTGTCCACGGGGGATCACCTCCACATGTGTGGAGAATACCTTTTCAAAGTCTCATTCACGCGATCATTTATAGGATCACCTCCACATGTGTGGAGAATACCATGGTACTAGTTGGAAAAATGCCGGGACACAGGGATCACCTCCACATGTGTGGAGAATACTATTTTTGATGAGTTTCTTACCAATAAATATTAGGATCACCTCCACATGTGTGGAGAATACCCTCAACCATCTTCCACAGTTGAGACCACCAAGGGATCACCTCCACATGTGTGGAGAATACACTATGACTATAACACTTCAAAAAATGAACCAGGGATCACCTCCACATGTGTGGAGAATAC

>NZ_CP039266|2|2|1207296-1208177|CRISPRCasFinder
TAACACTCTCAACATGTGTGGAGAATAC	CTTCGGCACCCTCAGCGAAATTAGACGGTATAA
GGATCACCTCCACATGTGTGGAGAATAC	CATACTTATAAAATCTCCAAGGTTGATAACAGA
GGATCACCTCCACATGTGTGGAGAATAC	ACAAAAGTTAAAAGCCGTTCAAGTGTTCACTTA
GGATCACCTCCACATGTGTGGAGAATAC	ACACTAAGAAAGTACCTGGTAATGTTTGGAATA
GGATCACCTCCACATGTGTGGAGAATAC	TAGTATCTGAATCAACCGTGCCGTTAACGGTGA
GGATCACCTCCACATGTGTGGAGAATAC	ATGACACAACATCTTTTAAAGGTTCAAGAAGTA
GGATCACCTCCACATGTGTGGAGAATAC	CAAGTGGTGTTGTGTCTGCGATGTCTCCACCAA
GGATCACCTCCACATGTGTGGAGAATAC	ATTTAGATTTAAACCGTTATACTGGTTCAATCG
GGATCACCTCCACATGTGTGGAGAATAC	CTCATATCTAGTTTACGATTATCTGTCCACGGG
GGATCACCTCCACATGTGTGGAGAATAC	CTTTTCAAAGTCTCATTCACGCGATCATTTATA
GGATCACCTCCACATGTGTGGAGAATAC	CATGGTACTAGTTGGAAAAATGCCGGGACACAG
GGATCACCTCCACATGTGTGGAGAATAC	TATTTTTGATGAGTTTCTTACCAATAAATATTA
GGATCACCTCCACATGTGTGGAGAATAC	CCTCAACCATCTTCCACAGTTGAGACCACCAAG
GGATCACCTCCACATGTGTGGAGAATAC	ACTATGACTATAACACTTCAAAAAATGAACCAG
GGATCACCTCCACATGTGTGGAGAATAC

>NZ_CP039266|2|2|1207296-1208177|CRT
TAACACTCTCAACATGTGTGGAGAATAC	CTTCGGCACCCTCAGCGAAATTAGACGGTATAA
GGATCACCTCCACATGTGTGGAGAATAC	CATACTTATAAAATCTCCAAGGTTGATAACAGA
GGATCACCTCCACATGTGTGGAGAATAC	ACAAAAGTTAAAAGCCGTTCAAGTGTTCACTTA
GGATCACCTCCACATGTGTGGAGAATAC	ACACTAAGAAAGTACCTGGTAATGTTTGGAATA
GGATCACCTCCACATGTGTGGAGAATAC	TAGTATCTGAATCAACCGTGCCGTTAACGGTGA
GGATCACCTCCACATGTGTGGAGAATAC	ATGACACAACATCTTTTAAAGGTTCAAGAAGTA
GGATCACCTCCACATGTGTGGAGAATAC	CAAGTGGTGTTGTGTCTGCGATGTCTCCACCAA
GGATCACCTCCACATGTGTGGAGAATAC	ATTTAGATTTAAACCGTTATACTGGTTCAATCG
GGATCACCTCCACATGTGTGGAGAATAC	CTCATATCTAGTTTACGATTATCTGTCCACGGG
GGATCACCTCCACATGTGTGGAGAATAC	CTTTTCAAAGTCTCATTCACGCGATCATTTATA
GGATCACCTCCACATGTGTGGAGAATAC	CATGGTACTAGTTGGAAAAATGCCGGGACACAG
GGATCACCTCCACATGTGTGGAGAATAC	TATTTTTGATGAGTTTCTTACCAATAAATATTA
GGATCACCTCCACATGTGTGGAGAATAC	CCTCAACCATCTTCCACAGTTGAGACCACCAAG
GGATCACCTCCACATGTGTGGAGAATAC	ACTATGACTATAACACTTCAAAAAATGAACCAG
GGATCACCTCCACATGTGTGGAGAATAC

>NZ_CP039266|2|2|1207357-1208177|PILER-CR
GGATCACCTCCACATGTGTGGAGAATAC	CATACTTATAAAATCTCCAAGGTTGATAACAGA
GGATCACCTCCACATGTGTGGAGAATAC	ACAAAAGTTAAAAGCCGTTCAAGTGTTCACTTA
GGATCACCTCCACATGTGTGGAGAATAC	ACACTAAGAAAGTACCTGGTAATGTTTGGAATA
GGATCACCTCCACATGTGTGGAGAATAC	TAGTATCTGAATCAACCGTGCCGTTAACGGTGA
GGATCACCTCCACATGTGTGGAGAATAC	ATGACACAACATCTTTTAAAGGTTCAAGAAGTA
GGATCACCTCCACATGTGTGGAGAATAC	CAAGTGGTGTTGTGTCTGCGATGTCTCCACCAA
GGATCACCTCCACATGTGTGGAGAATAC	ATTTAGATTTAAACCGTTATACTGGTTCAATCG
GGATCACCTCCACATGTGTGGAGAATAC	CTCATATCTAGTTTACGATTATCTGTCCACGGG
GGATCACCTCCACATGTGTGGAGAATAC	CTTTTCAAAGTCTCATTCACGCGATCATTTATA
GGATCACCTCCACATGTGTGGAGAATAC	CATGGTACTAGTTGGAAAAATGCCGGGACACAG
GGATCACCTCCACATGTGTGGAGAATAC	TATTTTTGATGAGTTTCTTACCAATAAATATTA
GGATCACCTCCACATGTGTGGAGAATAC	CCTCAACCATCTTCCACAGTTGAGACCACCAAG
GGATCACCTCCACATGTGTGGAGAATAC	ACTATGACTATAACACTTCAAAAAATGAACCAG
GGATCACCTCCACATGTGTGGAGAATAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP039266.1\|WP_001814874.1\|1191945_1192029_-\|23S-rRNA-methyltransferase-attenuation-leader-peptide	unknown	unknown	gnl\|CDD\|368836
NZ_CP039266.1\|WP_158181936.1\|1219270_1219474_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039266.1\|WP_158181922.1\|1191074_1191821_-\|23S-rRNA-(adenine(2058)-N(6))-methyltransferase-Erm(B)	unknown	unknown	gnl\|CDD\|366074
NZ_CP039266.1\|WP_158181925.1\|1193907_1201479_-\|YSIRK-type-signal-peptide-containing-protein	unknown	unknown	gnl\|CDD\|375451
NZ_CP039266.1\|WP_005719132.1\|1208609_1209233_+\|M23-family-metallopeptidase	unknown	unknown	gnl\|CDD\|366703
NZ_CP039266.1\|WP_101887418.1\|1209303_1209870_-\|peptide-methionine-(S)-S-oxide-reductase-MsrA	unknown	unknown	gnl\|CDD\|376578
NZ_CP039266.1\|WP_158181935.1\|1216432_1219270_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|366645
NZ_CP039266.1\|WP_158181931.1\|1213989_1214877_-\|lysin	unknown	unknown	gnl\|CDD\|119377
NZ_CP039266.1\|WP_158181932.1\|1214936_1215269_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|320630
NZ_CP039266.1\|WP_057727000.1\|1211690_1212569_-\|YitT-family-protein	unknown	unknown	gnl\|CDD\|224203
NZ_CP039266.1\|WP_158181929.1\|1206387_1206945_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039266.1\|WP_158181934.1\|1216028_1216421_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039266.1\|WP_057726630.1\|1203579_1203810_-\|heavy-metal-associated-domain-containing-protein	unknown	unknown	gnl\|CDD\|238219
NZ_CP039266.1\|WP_158181924.1\|1192565_1193837_+\|ISL3-family-transposase	unknown	unknown	gnl\|CDD\|225995
NZ_CP039266.1\|WP_158181928.1\|1203885_1205739_-\|cadmium-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319774
NZ_CP039266.1\|WP_158181926.1\|1202379_1203015_-\|cyclic-nucleotide-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|223736
NZ_CP039266.1\|WP_158181933.1\|1215271_1215502_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039266.1\|WP_158181927.1\|1203034_1203580_-\|DNA-binding-protein	unknown	unknown	unknown
NZ_CP039266.1\|WP_158181923.1\|1192077_1192317_-\|peptide-binding-protein	unknown	unknown	gnl\|CDD\|311623
NZ_CP039266.1\|WP_158181930.1\|1213020_1213878_-\|SEC10/PgrA-surface-exclusion-domain-containing-protein	unknown	unknown	gnl\|CDD\|275124

Protein	Function_ID	Function_description	E-value
NZ_CP039266.1\|WP_001814874.1\|1191945_1192029_-\|23S-rRNA-methyltransferase-attenuation-leader-peptide	gnl\|CDD\|368836	pfam06308, ErmC, 23S rRNA methylase leader peptide (ErmC). This family consists of several very short bacterial 23S rRNA methylase leader peptide (ErmC) sequences. ermC confers resistance to macrolide-lincosamide streptogramin B antibiotics by specifying a ribosomal RNA methylase, which results in decreased ribosomal affinity for these antibiotics. ermC expression is induced by exposure to erythromycin.	0.00200655
NZ_CP039266.1\|WP_158181922.1\|1191074_1191821_-\|23S-rRNA-(adenine(2058)-N(6))-methyltransferase-Erm(B)	gnl\|CDD\|366074	pfam00398, RrnaAD, Ribosomal RNA adenine dimethylase.	7.0568e-86
NZ_CP039266.1\|WP_158181925.1\|1193907_1201479_-\|YSIRK-type-signal-peptide-containing-protein	gnl\|CDD\|375451	pfam17966, Mub_B2, Mub B2-like domain. This entry corresponds to the Mub B2 domain. This domain is related to the Mub B1 domain pfam17965. This domain may be involved in mucin binding. This domain is often found associated with the related pfam17965 in bacterial cell surface proteins.	2.91775e-11
NZ_CP039266.1\|WP_005719132.1\|1208609_1209233_+\|M23-family-metallopeptidase	gnl\|CDD\|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	3.51871e-12
NZ_CP039266.1\|WP_101887418.1\|1209303_1209870_-\|peptide-methionine-(S)-S-oxide-reductase-MsrA	gnl\|CDD\|376578	pfam01625, PMSR, Peptide methionine sulfoxide reductase. This enzyme repairs damaged proteins. Methionine sulfoxide in proteins is reduced to methionine.	1.8503e-98
NZ_CP039266.1\|WP_158181935.1\|1216432_1219270_-\|hypothetical-protein	gnl\|CDD\|366645	pfam01442, Apolipoprotein, Apolipoprotein A1/A4/E domain. These proteins contain several 22 residue repeats which form a pair of alpha helices. This family includes: Apolipoprotein A-I. Apolipoprotein A-IV. Apolipoprotein E.	0.00155693
NZ_CP039266.1\|WP_158181931.1\|1213989_1214877_-\|lysin	gnl\|CDD\|119377	cd06415, GH25_Cpl1-like, Cpl-1 lysin (also known as Cpl-9 lysozyme / muramidase) is a bacterial cell wall endolysin encoded by the pneumococcal bacteriophage Cp-1, which cleaves the glycosidic N-acetylmuramoyl-(beta1,4)-N-acetylglucosamine bonds of the pneumococcal glycan chain, thus acting as an enzymatic antimicrobial agent (an enzybiotic) against streptococcal infections. Cpl-1 belongs to the CP family of lysozymes (CPL lysozymes) which includes the Cpl-7 lysin. Cpl-1 has a glycosyl hydrolase family 25 (GH25) catalytic domain with an irregular (beta/alpha)5-beta3 barrel and a C-terminal cell wall-anchoring module formed by six similar choline-binding repeats (ChBr's). The ChBr's facilitate the anchoring of Cpl-1 to the choline-containing teichoic acid of the pneumococcal cell wall. Other members of this domain family have an N-terminal CHAP (cysteine, histidine-dependent amidohydrolases/peptidases) domain similar to that of the firmicute CHAP lysins and associated with endopeptidase activity. The Cpl-7 lysin is also included here as is LysB of Lactococcus phage, and the Mur lysin of Lactobacillus phage.	7.9985e-80
NZ_CP039266.1\|WP_158181932.1\|1214936_1215269_-\|hypothetical-protein	gnl\|CDD\|320630	cd15964, 7tmA_TSH-R, thyroid-stimulating hormone receptor (or thyrotropin receptor), member of the class A family of seven-transmembrane G protein-coupled receptors. The glycoprotein hormone receptors are seven transmembrane domain receptors with a very large extracellular N-terminal domain containing many leucine-rich repeats responsible for hormone recognition and binding. The glycoprotein hormone family includes the three gonadotropins: luteinizing hormone (LH), follicle-stimulating hormone (FSH), chorionic gonadotropin (CG), and a pituitary thyroid-stimulating hormone (TSH). The glycoprotein hormones exert their biological functions by interacting with their cognate GPCRs. Both LH and CG bind to the same receptor, the luteinizing hormone-choriogonadotropin receptor (LHCGR); FSH binds to FSH-R and TSH to TSH-R. TSH-R plays an important role thyroid physiology, and its activation stimulates the production of thyroxine (T4) and triiodothyronine (T3). Defects in TSH-R are a cause of several types of hyperthyroidism. The receptor is predominantly found on the surface of the thyroid epithelial cells and couples to the G(s)-protein and activates adenylate cyclase, thereby promoting cAMP production. TSH and cAMP stimulate thyroid cell proliferation, differentiation, and function.	0.000448458
NZ_CP039266.1\|WP_057727000.1\|1211690_1212569_-\|YitT-family-protein	gnl\|CDD\|224203	COG1284, COG1284, Uncharacterized conserved protein [Function unknown].	6.21409e-63
NZ_CP039266.1\|WP_158181923.1\|1192077_1192317_-\|peptide-binding-protein	gnl\|CDD\|311623	pfam07764, Omega_Repress, Omega Transcriptional Repressor. The omega transcriptional repressor regulates expression of involved in copy number control and stable maintenance of plasmids. The omega protein belongs to the structural superfamily of MetJ/Arc repressors featuring a ribbon-helix-helix DNA-binding motif with the beta-ribbon located in and recognising the major groove of operator DNA.	1.46936e-34
NZ_CP039266.1\|WP_158181924.1\|1192565_1193837_+\|ISL3-family-transposase	gnl\|CDD\|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	7.18061e-53
NZ_CP039266.1\|WP_158181928.1\|1203885_1205739_-\|cadmium-translocating-P-type-ATPase	gnl\|CDD\|319774	cd02079, P-type_ATPase_HM, P-type heavy metal-transporting ATPase. Heavy metal-transporting ATPases (Type IB ATPases) transport heavy metal ions (Cu(+), Cu(2+), Zn(2+), Cd(2+), Co(2+), etc.) across biological membranes. These ATPases include mammalian copper-transporting ATPases, ATP7A and ATP7B, Bacillus subtilis CadA which transports cadmium, zinc and cobalt out of the cell, Bacillus subtilis ZosA/PfeT which transports copper, and perhaps also zinc and ferrous iron, Archaeoglobus fulgidus CopA and CopB, Staphylococcus aureus plasmid pI258 CadA, a cadmium-efflux ATPase, and Escherichia coli ZntA which is selective for Pb(2+), Zn(2+), and Cd(2+). The characteristic N-terminal heavy metal associated (HMA) domain of this group is essential for the binding of metal ions. This family belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_CP039266.1\|WP_158181926.1\|1202379_1203015_-\|cyclic-nucleotide-binding-domain-containing-protein	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	5.69104e-31
NZ_CP039266.1\|WP_057726630.1\|1203579_1203810_-\|heavy-metal-associated-domain-containing-protein	gnl\|CDD\|238219	cd00371, HMA, Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain contains two cysteine residues that are important in binding and transfer of metal ions, such as copper, cadmium, cobalt and zinc. In the case of copper, stoichiometry of binding is one Cu+ ion per binding domain. Repeats of the HMA domain in copper chaperone has been associated with Menkes/Wilson disease due to binding of multiple copper ions.	4.41057e-12
NZ_CP039266.1\|WP_158181930.1\|1213020_1213878_-\|SEC10/PgrA-surface-exclusion-domain-containing-protein	gnl\|CDD\|275124	TIGR04320, hypothetical_protein, SEC10/PgrA surface exclusion domain. This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.	1.11968e-26

>NZ_CP039266.1|WP_158181929.1|1206387_1206945_-|hypothetical-protein
MVDYIAKIKPINADKIETQAHGIATFSENGNSLHIHVEMFDTPANIEHWEHFHGFPDGKQAHVPTLMQDVNHDGFIDLPETEAVSGTTMVPFDDAPQEMNIPHDGYPVADKYGHYEYDKDVPLKDLQAKFKQAFGSDDLQLDKRVVYVHGVPADLKLPSSVAGNVMSYDAYTTLPIAAGEIKLAH
>NZ_CP039266.1|WP_158181928.1|1203885_1205739_-|cadmium-translocating-P-type-ATPase
MIKLQQFFMRYKKQLLLVNTILLLLAEGSKWLLQMNLPYQALMLIVGIVGVLPIALTAISSLRVKLIPIDVLVSLAVIGAFIIGEFNEAAIVTWLFMLGDVLEELTLKKTRSAVADLTKMAPQTALVVQDDGSTEKEDVDFIDPGEKILVKTGDQVPVDGKVISGSGYLNEASVNGESKLVNKKAGNEVYAGTILENGTLTVETTAVGEDTTFGKIIEMVEEAQDTKSHTEKLINRFSKYYTPAVLIIAIVVGLITKDLRLAITVMVLGCPGALVIGVPVSTVAGIGNGAKSGIMFKGSQVMDQTHRIDEIAFDKTGTLTVGHPEVSAIEILNGPKDEIIKLAAQIERQSNHPLAQAIAKLNKQKPDSIKVETVKGKGIIATLNNQKYYLGNQDLIVENTRTNAKLDKTINHLSQLGTSIVAFANEDQSQLAVFGIKDQLRPEANDALTRLKELGVKKLVMLSGDNQETAERIAAKLPIDEVHGQMLPQDKAAFVKKERAKGHHIAFIGDGINDSPALANANVAIAVGSGTDVAIEVSDIVLVKNDLRKIAYALGLSKKTILNMNENIVMALLTVLLLFIGLFAGYVEMASGMFIHEFSILIVILNGMRLIKFQQKN
>NZ_CP039266.1|WP_057726630.1|1203579_1203810_-|heavy-metal-associated-domain-containing-protein
MKKVMMKLSGMTCPSCLSKIERAVGSLDGTDQIKVLFNAGKLKFTLDPDKTKTVDVKTAIEKMGYEVQGIKEKELN
>NZ_CP039266.1|WP_158181927.1|1203034_1203580_-|DNA-binding-protein
MNAEEKYQAELKQSDLDHHQPTAAAMTGHITSNLLIHSLKINQANLFAKGSASLFLAEKAAGWIAYERQEFDQLNHLLVNNGESIPTITAQFKEYTMLEEDGSSKYLAGDKQLFALVKDFDTQTLFITKAIALANNESWPELSANLTNLMAWIKEQIRVTQDFLGHELKEGLYVEDDDDDF
>NZ_CP039266.1|WP_158181926.1|1202379_1203015_-|cyclic-nucleotide-binding-domain-containing-protein
MADLCVNLVPLFNALPQDDKMQIEELVQHKNYQKGEVIIDPTINDNLVIIADGNAKQYTLDENGYENVLQILHTGDYIGEDWLLGQENINNYLEATEHSEICLLKRQDLLKLMHKRPELSIQLLELNIVKVSEMQKQIHLLALPKVEDRLLKYLQTYADEIGKNNFTLPLKMKDLALYLGTTPETLSRKFALLEKQGQLKRQLRRIELFEN
>NZ_CP039266.1|WP_158181925.1|1193907_1201479_-|YSIRK-type-signal-peptide-containing-protein
MLFNKHSETKQRFGIRKLTIGACSVLLSTLFLTVNNGQQVNAATGDTVTNADNNKTETDNESVTKENEATKTNNDSSVSLNKDATEVTNTSNGTDSTEKQTTETEIEDKSADATTNGSAKADATKATEDKLSDSSSDQKLTEDKSANNEKQNQQQDKTATDAKSSDTSEKSEKAVTIANNKLAKAVVKLAVTPANNKLAKAVVKLAVIPANNKLAKATVNKLAVTTDDSTPVLSQSTENGDMTLSISLPELSNKDYIPQTIKLNATNVNSGDKIVIKVKKGSAYGFAKENFPIGTVTDFDQGAYKVFQIVLNTTGKFEYKISATRNNNYLAQPSPMEDTGVTTKDIQWSINGEDQAPLSFKQTIIPELISNGVSLAKATGDKNTDFTEVAPNEDYNFVYVMGENDGLVHDGSYMANVVNSAVNYGTTITIPVPENFLLNQEASDKANKERGLTGFTMTQDGMGKDVIITVPKGQSGLAWNHRGVYYTLTGKFVYDQIPEEPTTVTAKGDSVIDQIYTSDGQRITAKGKPFSVTISGKKGRPASGPLSLSVSGAISNNQLLLDSNPNNDPVAVNWFGYSNDYDNIENAKIKLDLADGLYVTGIKTPKDLGTVYNNIGNIQSYTYEMTLTNGQKITGTVKAGDIAKSTVTTTDADNKQTIIGIRNIVFTPDTNTIGKDTKTDDIPKPGSIADQEDRIDGTKTSNVFIALGHLSHTYDNGSQVKANDKLTSSITIFGSNFRPGWNNKPIVSYTASNTQTVFDTSQYKASLSAYNDPNYTSTQPGKENAGTISLNNGDGRSNYDYIFEPIFYYVVPDNAVYSGGAISRLNSNGNESPVPVVTTYFVNGHQVVKLDYSNTNYYYNTKYGTNNGIPLDNVNNQTSNTRSWEIYAYSKDIPLLNNSYTSGKFLTPETAEKSGSTLKLDPSKFYYVGGGTWTINTASAVVLADAANGNKNPDGLYAQNGTSDDKGSDGMNFRVNVVNYDMTTDLKDLTGFINLPVKGYNNTTTNFFLSGPVDVPDGTVLYSTSSTDLPSGRGTKTPSTDNFLTEEQVKAEIASGQMSSWSDVKSIAVKYDTVKANSATKDIYIHGTDPDITTDAGKVAQISWGLYGGNGMPPLVKKNASSIVISGSSTVKTRLHYIDPKGKDQYVDVPTMSKIYKDNSDTMRDSDFNEKNIPASLIPQGYELVLQNGKAIKSIINNGGTTWATHAEDGSAQFGKLVLYNFDGDTVQFELTPKIDKATQTVNRTVHFVSDGDNPQKLANDVYETAKITELTNEVTGEKQYSATITAGGVTTDAPVVVGQDGQISISFPATTIPGVNNYYVVDSTKSEADAISPTFTFTKDGNLVIKNTVKYAPVKQELQVQVYDDDADDPSQALDTTKTGATVDFTGDSFTNFPSDVATNVDSLIKYYTDRGYLIKTKPSDEELSGKFDGDKTQTQYLKLQLVHDKATVSGEDENTPAPDTPINENDPDGVKYPSDVSKDNLVISSKNIIHYYDEAGNKILDDKVNTDDSTLTRTVTIDKVTGKVTNTSDWTGGKEYENVNTPVVNGYYVDKASASAGASTVTPADANSGRVHDGVITNETTVIYHPMGHIIPIDKSGNKIPGAETPIFTNDTKDPTKASTTNSPIIPGYHLETPSDSAITPDEPGKDRPVVYVADTQELKVQVFDLDGDTPDEPLKTDKTGATVDFTGDSFTNFPSDVATNVDSLIKYYTDRGYLIKTKPSDEELSGKFDGDKTQTQYLKLQLVHDKATVSGEDENTPAPDTPINENDPDGVKYPSDVSKDNLVISSKNIIHYYDEAGNKILDDKVNTDDSTLTRTVTIDKVTGKVTNTSDWTGGKEYENVNTPVVNGYYVDKASASAGASTVTPADANSGRVHDGVITNETTVIYHPMGHIIPIDKSGNKIPGAETPIFTNDTKDPTKASTTNSPIIPGYHLETPSDSAITPDEPGKDRPVVYVADTQELKVQVFDLDGDTPDEPLKTDKTGATVDFTGDSFTNFPSDVATNVDSLIKYYTDRGYLIKTKPSDEELSGKFDGDKTQTQYLKLQLVHDKATVSGEDENTPAPDTPINENDPDGVKYPSDVSKDNLVISSEVIIHYEGAGEKTPKNVIRTVDKTLTRTVTIDKVTGKVTNTSDWSSNTTEYESVLTPQIQGYTSDKVQVDKVSITKDNAGEAKNGKITYTFNVVYTPDKQQLILKVHDEDTQSYLGDPVIFDGYTDQEVGNSPVDKLEELKKKYLDLGYEIVEIPQLDKNYDDTPNVGGEPDKEPQVFVLKVKHRIVPVTPDDPKTPDDIIPDSNQNYPGGLTETDLSRTITRTIVVNFPSGTSQEIKQVVTYTRTATVDAVTKEVKYSAWTTKNSNWPKYVAPVVPGYTPDKDMIELTYVPADGKDVTVEINYTADPEPDEPTTPVKPGEPITPVTPTTPTTPTKPVKPTKPSKPKKPAKQTKPEVVKPVKETKGKQLYGSAQAKVDSKAAQNVVDKNKANGTNDKKLPQTNGESNWQLSLLGVGVLALALLVLKKKRDDE
>NZ_CP039266.1|WP_158181924.1|1192565_1193837_+|ISL3-family-transposase
MSSLNDYIKFTLDVEDKNIIFSDYSNENINGKIYKIYLAELIQPTCPYCRSTNLKHNGHYVSNVRFITADASKPVTIRLRKQRVLCNDCLKRSMAQSNLVNKGSYISNTSKRKILSALTEDRSMTSIAREHNVSVNTVQRVLEACSSKFYDDFDHLPEHLAFDEFKGVGKKLHFICLDGDTHKVVQILRTRFKPDILRYFYKFTPKARAMVKTVTMDLNCYYPLVARKLFPNAQIVIDRFHMVQMLTRSFNIFRVQIMKQFNKRSREYKLLKSPWKLYLMKYDKLNKTTPYYDWHFKDCLTQEHVVLDGLDCDQTLENTYWVMQDFMTAIQDNDEKKVIHLLHSKQSVGKQMHQTLLTFKHNYSGVLNGISSTYSNGCLEGVNRKIKQIERTAYGYRNFSHLLIRLEENIVKEKESSNFFFVA
>NZ_CP039266.1|WP_158181923.1|1192077_1192317_-|peptide-binding-protein
MIVGNLGAQKEKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAKNGGNVKEVMEIRLRSKLKRVLIVHYLKILYNRN
>NZ_CP039266.1|WP_001814874.1|1191945_1192029_-|23S-rRNA-methyltransferase-attenuation-leader-peptide
MLVFQMRNVDKTSTVLKQTKNSDYADK
>NZ_CP039266.1|WP_158181922.1|1191074_1191821_-|23S-rRNA-(adenine(2058)-N(6))-methyltransferase-Erm(B)
MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLTTKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIPYNLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAECFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHAKVNNLSTITYEQVLSIFNSYLLFNGRKLIL
>NZ_CP039266.1|WP_005719132.1|1208609_1209233_+|M23-family-metallopeptidase
MKFRKLIISLLGTALLTSSVGLSTTTASADTLDDSQNTTEVQPKNLKWAYPFKANKKNGVRPMYNAQTFGITNYMRSTTPPSYFHDGWDFGFSEVGHSNVYAIHQGTVKKVAYGNGLGWFIWVISPDNYVEVYQEGFNKKKDIYVKTGQKIKLGQKIGKLTGSHLHLGVTQTNKDYINKYGFPCKNWNVNNGTWLNPIEVIKSNLKK
>NZ_CP039266.1|WP_101887418.1|1209303_1209870_-|peptide-methionine-(S)-S-oxide-reductase-MsrA
MTENNKQAEGTDTKAKTNYDTAIFAGGCFWCMVEPFDTVDGVEKVVSGYTGGHVANPTYEQVCSGTTGHTEAVEITFDPAKISYDQLLNYYWQVTDPTDAMGQFQDRGDNYRPVIFYNSPAQKEAAEKSKQRLQASGKFDKPIVTKIEPAKPFYPAEEYHQDFYKKDPLRYAMEEAGGRAKFIKEHWD
>NZ_CP039266.1|WP_057727000.1|1211690_1212569_-|YitT-family-protein
MDQLDKFNRRYNFLSKLSAAFFYSIAVAVALNFFWTPGHMYSSGITGFAQLINTVSERYLPFTLSTSMMYFLLNFPLFILAWFKIGRKFTFFTIVAVVLGSIMMHAIQPWQMHLDPLVCAIFGASINGIGTGMALKNGISTGGLDIIGIVIRQKTGISYGKFNIFINLIIIAAAGYMFGWPRALYSALTIFINGRVIDAVYTQHQKMQVMIVTQHPQHIIDGIQNRMHRGITILHDAEGAYSHIEKTVLITIIDRYDMYDIRQIVQGADPYAFMSVSEVEKVYGRFKEQEIV
>NZ_CP039266.1|WP_158181930.1|1213020_1213878_-|SEC10/PgrA-surface-exclusion-domain-containing-protein
MNFKKIAILSASVLALSTCAVSVIESPSTHVVYAAKSKLKTRIAVPKGYTADLIEDWCDSPNNKKLTRKLKRLSRRGMLSNKFYDRRKADKRKVNLANLSNRDQYELSQYALTLINSIRTQLGLPKFTYTASAQSFANDIAKAYNKDNWSDYQGHDISAINRTAKQHGLTKNDNEYEDMGGFDITTGHQYATIYQIKQNIYYNIKQAAFGGFWYHNNQESDKYNLNYYTEWNHANDLFTGDYSQEFALSLSYLIQDPTNKVNKITSSHYIHVDPENIEKKALYEK
>NZ_CP039266.1|WP_158181931.1|1213989_1214877_-|lysin
MTKTYLVDVAKYQPNSLRTYKNAGAKSAIVQVSVAKSIVAPKAKAQVKSAKANGLVPMGYFYACFGNSVSEAEAESRFAVSQAEAAGIPAGSFLGVDWESQDNNTSNGSRSNTNAILAAMDVIKKAGYKPLLYSSASLMRTKIDTARVTDKYGTCLWVASYPYSGATYSPDFRYFPSMKGVAIWQFTDNWKGLSVDGNVGFISFEPARVKITKVKHASWHAQKGVFVLGQALELHKSPHVSSPAIAKLEKGASVVYDATLQGPLRLWIRQPREKGYGYMVAKDRYGRFLGKMITK
>NZ_CP039266.1|WP_158181932.1|1214936_1215269_-|hypothetical-protein
MNYISEISTIAIIAFVSLCVCYMFFYENISKKDPQKVSDSKYKDIYEIAKLIVDDFDPTGLKPLKPEDHQQAVAKVQDQAQKDGLDVTQAVASGAVKKAVQDKQQESPKN
>NZ_CP039266.1|WP_158181933.1|1215271_1215502_-|hypothetical-protein
MNADLYAVLASGAVGGIISAIASGIVEYKKLKDSETYQAEKDEREQIEFYRQKWLEDEDQIDKLRDELRTLKDKEK
>NZ_CP039266.1|WP_158181934.1|1216028_1216421_-|hypothetical-protein
MKKVFTYARAQLERHPLHIILALVLIGLGAFLIANDSYFTWPPALQAVVNSDFFGTWAIFNGLGLLYVAFSKPWPYRANLIWLMSTAGFLGCETAMEIAHDVLGKADHTTGFLVLVLGYLILAFVIAKKD
>NZ_CP039266.1|WP_158181935.1|1216432_1219270_-|hypothetical-protein
MDLQKVTLPLLILDVEHNDQKQALAHVLNQHDAGYVQPFILNSGDDAYDVPAEDFHFRASLPDNQIIDVDNSNGDLVQKGDQNWLLNLPTGVTGVPGLVKCVVYAKDDGRVLASSQQIMYNVMPAFDVEDASHVSYVPDLDKLKANLQNLLGKAQDQVTRLSGITAGDKQAAEQALKEELDKLGKQAGDWLDGEKANVNKQIADIVKQSSGLDEAYKQAYKEEIDKLAGQTGKDYEAKLQAVIDKLNNDKQASLQAINDDWTKQKVSLQTDIAGFKDNLTKQVEAITSTVNALNTSDLPAIQSKVNSFKDALDKLNSQISAIKLDYYTKDEIDNKLDSLKAGATPDLTDLKKQVQDNTTSLQSKVGKDELTNYALKSDVTQPDLTGYATTQALTDGLSNKADKNALDAYALKSELPAMPDLSAYAKVTALENYATKQALNAYALKTDLPDLTSYAKKSDLPDISGLETQADHANDVKKINETLETYAKKSELPDISGLETKADHKADVDKLNKALDSKADKTALDAYALKKDVPASPDLSGYAKTADLAAYETSASHKADIDKLNKALEAKADISAIPALPDMSQYALKTDLKNVDLTGYLTKDDADRLLGEKANESELADYAKKTDLPPVPNLTVYAKVTDVAKALNNKADTDALREYAKTADVERVNKAATHANIVANFAMQNSQSAVYGIQVDDGPLLPKAHGHINLPLGLSDYLKKADADNEYAKKTDIPAIPDTSNFVTNDSLTDKLQNYNGGYLTNWDAAQKYETAAQVQELINGQLGNIHEEYAPRALLNDYTQTADLPKYLSDNYGLANQVGDVHPLINSIRGLTYLTSATPEYSDSHNSEADKNGVIDVNKDAPYASGPVIFPSVLNTNASTVDMLNSYSRANKNYILSTWITTKNKDGSQNTDLRYSIGGNELALMSDISALSDRVKALEQKLNK
>NZ_CP039266.1|WP_158181936.1|1219270_1219474_-|hypothetical-protein
MNDTNETNEIFASDAMQIIKVYMQQKAALQSRVLELEKENENLKHELQELAEKHDKNVIKLDQKEGK

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Crispr_ID: NZ_CP039266_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP039266_3

1210906-1211472

Orphan

I-B,III-A,III-B:NA

Consensus_repeat	Method
GGATGACCTCCACATACGTGGAGAATAC	CRISPRCasFinder
ACCTCCACATACGTGGAGAATAC	CRT
GGATGACCTCCACATACGTGGAGAATAC	PILER-CR

9 spacers

The CRISPR arrays of NZ_CP039266_3

>merge|NZ_CP039266|3|1210906-1211472|CRISPRCasFinder,CRT,PILER-CR
ATTTAGCCTCCACATGTGTGGAGAATTCAGTTTTTTAGTCAGTCACGTAAAGGATCACCTCCACATACGTGGAGAATACTAGCTCCACAATGCATCCCACTTTCTGCTGTTAGGATCACCTCCACACTCGTGGAGAATACGATTTTGATCGTCAAAAAATGGTACCTAAACTGGGATGACCTCCACATACGTGGAGAATACCTTGTGAACTCATGGGATAGAAAGGCTAATACAGGATGACCTCCACATACGTGGAGAATACTTACTCATGCAAACCCCAACCACGTTGGCAAGGGGATGACCTCCACATACGTGGAGAATACAATAGAATTCAGAGATAGTTTAATTTTAAGTGGGGATGACCTCCACATACGTGGAGAATACTCAAGCCATTGTCCTAGACCAGCTGCCCCACCAGGATGACCTCCACATACGTGGAGAATACCATTTCTGAGTACATGCACATGAGAGGAGATGAGGATGACCTCCACATACGTGGAGAATACCACAAATTGAAGATACAATTTCTGCTGGTTATAGGATGACCTCCACATACGTGGAGAATAC

>NZ_CP039266|3|3|1210906-1211472|CRISPRCasFinder
ATTTAGCCTCCACATGTGTGGAGAATTC	AGTTTTTTAGTCAGTCACGTAAA
GGATCACCTCCACATACGTGGAGAATAC	TAGCTCCACAATGCATCCCACTTTCTGCTGTTA
GGATCACCTCCACACTCGTGGAGAATAC	GATTTTGATCGTCAAAAAATGGTACCTAAACTG
GGATGACCTCCACATACGTGGAGAATAC	CTTGTGAACTCATGGGATAGAAAGGCTAATACA
GGATGACCTCCACATACGTGGAGAATAC	TTACTCATGCAAACCCCAACCACGTTGGCAAGG
GGATGACCTCCACATACGTGGAGAATAC	AATAGAATTCAGAGATAGTTTAATTTTAAGTGG
GGATGACCTCCACATACGTGGAGAATAC	TCAAGCCATTGTCCTAGACCAGCTGCCCCACCA
GGATGACCTCCACATACGTGGAGAATAC	CATTTCTGAGTACATGCACATGAGAGGAGATGA
GGATGACCTCCACATACGTGGAGAATAC	CACAAATTGAAGATACAATTTCTGCTGGTTATA
GGATGACCTCCACATACGTGGAGAATAC

>NZ_CP039266|3|3|1210911-1211472|CRT
GCCTCCACATGTGTGGAGAATTC	AGTTTTTTAGTCAGTCACGTAAAGGATC
ACCTCCACATACGTGGAGAATAC	TAGCTCCACAATGCATCCCACTTTCTGCTGTTAGGATC
ACCTCCACACTCGTGGAGAATAC	GATTTTGATCGTCAAAAAATGGTACCTAAACTGGGATG
ACCTCCACATACGTGGAGAATAC	CTTGTGAACTCATGGGATAGAAAGGCTAATACAGGATG
ACCTCCACATACGTGGAGAATAC	TTACTCATGCAAACCCCAACCACGTTGGCAAGGGGATG
ACCTCCACATACGTGGAGAATAC	AATAGAATTCAGAGATAGTTTAATTTTAAGTGGGGATG
ACCTCCACATACGTGGAGAATAC	TCAAGCCATTGTCCTAGACCAGCTGCCCCACCAGGATG
ACCTCCACATACGTGGAGAATAC	CATTTCTGAGTACATGCACATGAGAGGAGATGAGGATG
ACCTCCACATACGTGGAGAATAC	CACAAATTGAAGATACAATTTCTGCTGGTTATAGGATG
ACCTCCACATACGTGGAGAATAC

>NZ_CP039266|3|3|1211079-1211472|PILER-CR
GGATGACCTCCACATACGTGGAGAATAC	CTTGTGAACTCATGGGATAGAAAGGCTAATACA
GGATGACCTCCACATACGTGGAGAATAC	TTACTCATGCAAACCCCAACCACGTTGGCAAGG
GGATGACCTCCACATACGTGGAGAATAC	AATAGAATTCAGAGATAGTTTAATTTTAAGTGG
GGATGACCTCCACATACGTGGAGAATAC	TCAAGCCATTGTCCTAGACCAGCTGCCCCACCA
GGATGACCTCCACATACGTGGAGAATAC	CATTTCTGAGTACATGCACATGAGAGGAGATGA
GGATGACCTCCACATACGTGGAGAATAC	CACAAATTGAAGATACAATTTCTGCTGGTTATA
GGATGACCTCCACATACGTGGAGAATAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP039266.1\|WP_005719132.1\|1208609_1209233_+\|M23-family-metallopeptidase	unknown	unknown	gnl\|CDD\|366703
NZ_CP039266.1\|WP_158181936.1\|1219270_1219474_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039266.1\|WP_158181934.1\|1216028_1216421_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039266.1\|WP_158181925.1\|1193907_1201479_-\|YSIRK-type-signal-peptide-containing-protein	unknown	unknown	gnl\|CDD\|375451
NZ_CP039266.1\|WP_158181932.1\|1214936_1215269_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|320630
NZ_CP039266.1\|WP_101887418.1\|1209303_1209870_-\|peptide-methionine-(S)-S-oxide-reductase-MsrA	unknown	unknown	gnl\|CDD\|376578
NZ_CP039266.1\|WP_158181935.1\|1216432_1219270_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|366645
NZ_CP039266.1\|WP_158181931.1\|1213989_1214877_-\|lysin	unknown	unknown	gnl\|CDD\|119377
NZ_CP039266.1\|WP_158181937.1\|1219485_1221744_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377677
NZ_CP039266.1\|WP_057727000.1\|1211690_1212569_-\|YitT-family-protein	unknown	unknown	gnl\|CDD\|224203
NZ_CP039266.1\|WP_158181929.1\|1206387_1206945_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039266.1\|WP_057726630.1\|1203579_1203810_-\|heavy-metal-associated-domain-containing-protein	unknown	unknown	gnl\|CDD\|238219
NZ_CP039266.1\|WP_158181938.1\|1221743_1222562_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368574
NZ_CP039266.1\|WP_158181924.1\|1192565_1193837_+\|ISL3-family-transposase	unknown	unknown	gnl\|CDD\|225995
NZ_CP039266.1\|WP_158181928.1\|1203885_1205739_-\|cadmium-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319774
NZ_CP039266.1\|WP_158181926.1\|1202379_1203015_-\|cyclic-nucleotide-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|223736
NZ_CP039266.1\|WP_158181933.1\|1215271_1215502_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039266.1\|WP_158181927.1\|1203034_1203580_-\|DNA-binding-protein	unknown	unknown	unknown
NZ_CP039266.1\|WP_158181923.1\|1192077_1192317_-\|peptide-binding-protein	unknown	unknown	gnl\|CDD\|311623
NZ_CP039266.1\|WP_158181930.1\|1213020_1213878_-\|SEC10/PgrA-surface-exclusion-domain-containing-protein	unknown	unknown	gnl\|CDD\|275124

Protein	Function_ID	Function_description	E-value
NZ_CP039266.1\|WP_005719132.1\|1208609_1209233_+\|M23-family-metallopeptidase	gnl\|CDD\|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	3.51871e-12
NZ_CP039266.1\|WP_158181925.1\|1193907_1201479_-\|YSIRK-type-signal-peptide-containing-protein	gnl\|CDD\|375451	pfam17966, Mub_B2, Mub B2-like domain. This entry corresponds to the Mub B2 domain. This domain is related to the Mub B1 domain pfam17965. This domain may be involved in mucin binding. This domain is often found associated with the related pfam17965 in bacterial cell surface proteins.	2.91775e-11
NZ_CP039266.1\|WP_158181932.1\|1214936_1215269_-\|hypothetical-protein	gnl\|CDD\|320630	cd15964, 7tmA_TSH-R, thyroid-stimulating hormone receptor (or thyrotropin receptor), member of the class A family of seven-transmembrane G protein-coupled receptors. The glycoprotein hormone receptors are seven transmembrane domain receptors with a very large extracellular N-terminal domain containing many leucine-rich repeats responsible for hormone recognition and binding. The glycoprotein hormone family includes the three gonadotropins: luteinizing hormone (LH), follicle-stimulating hormone (FSH), chorionic gonadotropin (CG), and a pituitary thyroid-stimulating hormone (TSH). The glycoprotein hormones exert their biological functions by interacting with their cognate GPCRs. Both LH and CG bind to the same receptor, the luteinizing hormone-choriogonadotropin receptor (LHCGR); FSH binds to FSH-R and TSH to TSH-R. TSH-R plays an important role thyroid physiology, and its activation stimulates the production of thyroxine (T4) and triiodothyronine (T3). Defects in TSH-R are a cause of several types of hyperthyroidism. The receptor is predominantly found on the surface of the thyroid epithelial cells and couples to the G(s)-protein and activates adenylate cyclase, thereby promoting cAMP production. TSH and cAMP stimulate thyroid cell proliferation, differentiation, and function.	0.000448458
NZ_CP039266.1\|WP_101887418.1\|1209303_1209870_-\|peptide-methionine-(S)-S-oxide-reductase-MsrA	gnl\|CDD\|376578	pfam01625, PMSR, Peptide methionine sulfoxide reductase. This enzyme repairs damaged proteins. Methionine sulfoxide in proteins is reduced to methionine.	1.8503e-98
NZ_CP039266.1\|WP_158181935.1\|1216432_1219270_-\|hypothetical-protein	gnl\|CDD\|366645	pfam01442, Apolipoprotein, Apolipoprotein A1/A4/E domain. These proteins contain several 22 residue repeats which form a pair of alpha helices. This family includes: Apolipoprotein A-I. Apolipoprotein A-IV. Apolipoprotein E.	0.00155693
NZ_CP039266.1\|WP_158181931.1\|1213989_1214877_-\|lysin	gnl\|CDD\|119377	cd06415, GH25_Cpl1-like, Cpl-1 lysin (also known as Cpl-9 lysozyme / muramidase) is a bacterial cell wall endolysin encoded by the pneumococcal bacteriophage Cp-1, which cleaves the glycosidic N-acetylmuramoyl-(beta1,4)-N-acetylglucosamine bonds of the pneumococcal glycan chain, thus acting as an enzymatic antimicrobial agent (an enzybiotic) against streptococcal infections. Cpl-1 belongs to the CP family of lysozymes (CPL lysozymes) which includes the Cpl-7 lysin. Cpl-1 has a glycosyl hydrolase family 25 (GH25) catalytic domain with an irregular (beta/alpha)5-beta3 barrel and a C-terminal cell wall-anchoring module formed by six similar choline-binding repeats (ChBr's). The ChBr's facilitate the anchoring of Cpl-1 to the choline-containing teichoic acid of the pneumococcal cell wall. Other members of this domain family have an N-terminal CHAP (cysteine, histidine-dependent amidohydrolases/peptidases) domain similar to that of the firmicute CHAP lysins and associated with endopeptidase activity. The Cpl-7 lysin is also included here as is LysB of Lactococcus phage, and the Mur lysin of Lactobacillus phage.	7.9985e-80
NZ_CP039266.1\|WP_158181937.1\|1219485_1221744_-\|hypothetical-protein	gnl\|CDD\|377677	pfam06605, Prophage_tail, Prophage endopeptidase tail. This family is of prophage tail proteins that are probably acting as endopeptidases.	4.47985e-05
NZ_CP039266.1\|WP_057727000.1\|1211690_1212569_-\|YitT-family-protein	gnl\|CDD\|224203	COG1284, COG1284, Uncharacterized conserved protein [Function unknown].	6.21409e-63
NZ_CP039266.1\|WP_158181923.1\|1192077_1192317_-\|peptide-binding-protein	gnl\|CDD\|311623	pfam07764, Omega_Repress, Omega Transcriptional Repressor. The omega transcriptional repressor regulates expression of involved in copy number control and stable maintenance of plasmids. The omega protein belongs to the structural superfamily of MetJ/Arc repressors featuring a ribbon-helix-helix DNA-binding motif with the beta-ribbon located in and recognising the major groove of operator DNA.	1.46936e-34
NZ_CP039266.1\|WP_158181938.1\|1221743_1222562_-\|hypothetical-protein	gnl\|CDD\|368574	pfam05709, Sipho_tail, Phage tail protein. This family consists of several Siphovirus and other phage tail component proteins as well as some bacterial proteins of unknown function.	2.72793e-15
NZ_CP039266.1\|WP_158181924.1\|1192565_1193837_+\|ISL3-family-transposase	gnl\|CDD\|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	7.18061e-53
NZ_CP039266.1\|WP_158181928.1\|1203885_1205739_-\|cadmium-translocating-P-type-ATPase	gnl\|CDD\|319774	cd02079, P-type_ATPase_HM, P-type heavy metal-transporting ATPase. Heavy metal-transporting ATPases (Type IB ATPases) transport heavy metal ions (Cu(+), Cu(2+), Zn(2+), Cd(2+), Co(2+), etc.) across biological membranes. These ATPases include mammalian copper-transporting ATPases, ATP7A and ATP7B, Bacillus subtilis CadA which transports cadmium, zinc and cobalt out of the cell, Bacillus subtilis ZosA/PfeT which transports copper, and perhaps also zinc and ferrous iron, Archaeoglobus fulgidus CopA and CopB, Staphylococcus aureus plasmid pI258 CadA, a cadmium-efflux ATPase, and Escherichia coli ZntA which is selective for Pb(2+), Zn(2+), and Cd(2+). The characteristic N-terminal heavy metal associated (HMA) domain of this group is essential for the binding of metal ions. This family belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_CP039266.1\|WP_158181926.1\|1202379_1203015_-\|cyclic-nucleotide-binding-domain-containing-protein	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	5.69104e-31
NZ_CP039266.1\|WP_057726630.1\|1203579_1203810_-\|heavy-metal-associated-domain-containing-protein	gnl\|CDD\|238219	cd00371, HMA, Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain contains two cysteine residues that are important in binding and transfer of metal ions, such as copper, cadmium, cobalt and zinc. In the case of copper, stoichiometry of binding is one Cu+ ion per binding domain. Repeats of the HMA domain in copper chaperone has been associated with Menkes/Wilson disease due to binding of multiple copper ions.	4.41057e-12
NZ_CP039266.1\|WP_158181930.1\|1213020_1213878_-\|SEC10/PgrA-surface-exclusion-domain-containing-protein	gnl\|CDD\|275124	TIGR04320, hypothetical_protein, SEC10/PgrA surface exclusion domain. This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.	1.11968e-26

>NZ_CP039266.1|WP_101887418.1|1209303_1209870_-|peptide-methionine-(S)-S-oxide-reductase-MsrA
MTENNKQAEGTDTKAKTNYDTAIFAGGCFWCMVEPFDTVDGVEKVVSGYTGGHVANPTYEQVCSGTTGHTEAVEITFDPAKISYDQLLNYYWQVTDPTDAMGQFQDRGDNYRPVIFYNSPAQKEAAEKSKQRLQASGKFDKPIVTKIEPAKPFYPAEEYHQDFYKKDPLRYAMEEAGGRAKFIKEHWD
>NZ_CP039266.1|WP_005719132.1|1208609_1209233_+|M23-family-metallopeptidase
MKFRKLIISLLGTALLTSSVGLSTTTASADTLDDSQNTTEVQPKNLKWAYPFKANKKNGVRPMYNAQTFGITNYMRSTTPPSYFHDGWDFGFSEVGHSNVYAIHQGTVKKVAYGNGLGWFIWVISPDNYVEVYQEGFNKKKDIYVKTGQKIKLGQKIGKLTGSHLHLGVTQTNKDYINKYGFPCKNWNVNNGTWLNPIEVIKSNLKK
>NZ_CP039266.1|WP_158181929.1|1206387_1206945_-|hypothetical-protein
MVDYIAKIKPINADKIETQAHGIATFSENGNSLHIHVEMFDTPANIEHWEHFHGFPDGKQAHVPTLMQDVNHDGFIDLPETEAVSGTTMVPFDDAPQEMNIPHDGYPVADKYGHYEYDKDVPLKDLQAKFKQAFGSDDLQLDKRVVYVHGVPADLKLPSSVAGNVMSYDAYTTLPIAAGEIKLAH
>NZ_CP039266.1|WP_158181928.1|1203885_1205739_-|cadmium-translocating-P-type-ATPase
MIKLQQFFMRYKKQLLLVNTILLLLAEGSKWLLQMNLPYQALMLIVGIVGVLPIALTAISSLRVKLIPIDVLVSLAVIGAFIIGEFNEAAIVTWLFMLGDVLEELTLKKTRSAVADLTKMAPQTALVVQDDGSTEKEDVDFIDPGEKILVKTGDQVPVDGKVISGSGYLNEASVNGESKLVNKKAGNEVYAGTILENGTLTVETTAVGEDTTFGKIIEMVEEAQDTKSHTEKLINRFSKYYTPAVLIIAIVVGLITKDLRLAITVMVLGCPGALVIGVPVSTVAGIGNGAKSGIMFKGSQVMDQTHRIDEIAFDKTGTLTVGHPEVSAIEILNGPKDEIIKLAAQIERQSNHPLAQAIAKLNKQKPDSIKVETVKGKGIIATLNNQKYYLGNQDLIVENTRTNAKLDKTINHLSQLGTSIVAFANEDQSQLAVFGIKDQLRPEANDALTRLKELGVKKLVMLSGDNQETAERIAAKLPIDEVHGQMLPQDKAAFVKKERAKGHHIAFIGDGINDSPALANANVAIAVGSGTDVAIEVSDIVLVKNDLRKIAYALGLSKKTILNMNENIVMALLTVLLLFIGLFAGYVEMASGMFIHEFSILIVILNGMRLIKFQQKN
>NZ_CP039266.1|WP_057726630.1|1203579_1203810_-|heavy-metal-associated-domain-containing-protein
MKKVMMKLSGMTCPSCLSKIERAVGSLDGTDQIKVLFNAGKLKFTLDPDKTKTVDVKTAIEKMGYEVQGIKEKELN
>NZ_CP039266.1|WP_158181927.1|1203034_1203580_-|DNA-binding-protein
MNAEEKYQAELKQSDLDHHQPTAAAMTGHITSNLLIHSLKINQANLFAKGSASLFLAEKAAGWIAYERQEFDQLNHLLVNNGESIPTITAQFKEYTMLEEDGSSKYLAGDKQLFALVKDFDTQTLFITKAIALANNESWPELSANLTNLMAWIKEQIRVTQDFLGHELKEGLYVEDDDDDF
>NZ_CP039266.1|WP_158181926.1|1202379_1203015_-|cyclic-nucleotide-binding-domain-containing-protein
MADLCVNLVPLFNALPQDDKMQIEELVQHKNYQKGEVIIDPTINDNLVIIADGNAKQYTLDENGYENVLQILHTGDYIGEDWLLGQENINNYLEATEHSEICLLKRQDLLKLMHKRPELSIQLLELNIVKVSEMQKQIHLLALPKVEDRLLKYLQTYADEIGKNNFTLPLKMKDLALYLGTTPETLSRKFALLEKQGQLKRQLRRIELFEN
>NZ_CP039266.1|WP_158181925.1|1193907_1201479_-|YSIRK-type-signal-peptide-containing-protein
MLFNKHSETKQRFGIRKLTIGACSVLLSTLFLTVNNGQQVNAATGDTVTNADNNKTETDNESVTKENEATKTNNDSSVSLNKDATEVTNTSNGTDSTEKQTTETEIEDKSADATTNGSAKADATKATEDKLSDSSSDQKLTEDKSANNEKQNQQQDKTATDAKSSDTSEKSEKAVTIANNKLAKAVVKLAVTPANNKLAKAVVKLAVIPANNKLAKATVNKLAVTTDDSTPVLSQSTENGDMTLSISLPELSNKDYIPQTIKLNATNVNSGDKIVIKVKKGSAYGFAKENFPIGTVTDFDQGAYKVFQIVLNTTGKFEYKISATRNNNYLAQPSPMEDTGVTTKDIQWSINGEDQAPLSFKQTIIPELISNGVSLAKATGDKNTDFTEVAPNEDYNFVYVMGENDGLVHDGSYMANVVNSAVNYGTTITIPVPENFLLNQEASDKANKERGLTGFTMTQDGMGKDVIITVPKGQSGLAWNHRGVYYTLTGKFVYDQIPEEPTTVTAKGDSVIDQIYTSDGQRITAKGKPFSVTISGKKGRPASGPLSLSVSGAISNNQLLLDSNPNNDPVAVNWFGYSNDYDNIENAKIKLDLADGLYVTGIKTPKDLGTVYNNIGNIQSYTYEMTLTNGQKITGTVKAGDIAKSTVTTTDADNKQTIIGIRNIVFTPDTNTIGKDTKTDDIPKPGSIADQEDRIDGTKTSNVFIALGHLSHTYDNGSQVKANDKLTSSITIFGSNFRPGWNNKPIVSYTASNTQTVFDTSQYKASLSAYNDPNYTSTQPGKENAGTISLNNGDGRSNYDYIFEPIFYYVVPDNAVYSGGAISRLNSNGNESPVPVVTTYFVNGHQVVKLDYSNTNYYYNTKYGTNNGIPLDNVNNQTSNTRSWEIYAYSKDIPLLNNSYTSGKFLTPETAEKSGSTLKLDPSKFYYVGGGTWTINTASAVVLADAANGNKNPDGLYAQNGTSDDKGSDGMNFRVNVVNYDMTTDLKDLTGFINLPVKGYNNTTTNFFLSGPVDVPDGTVLYSTSSTDLPSGRGTKTPSTDNFLTEEQVKAEIASGQMSSWSDVKSIAVKYDTVKANSATKDIYIHGTDPDITTDAGKVAQISWGLYGGNGMPPLVKKNASSIVISGSSTVKTRLHYIDPKGKDQYVDVPTMSKIYKDNSDTMRDSDFNEKNIPASLIPQGYELVLQNGKAIKSIINNGGTTWATHAEDGSAQFGKLVLYNFDGDTVQFELTPKIDKATQTVNRTVHFVSDGDNPQKLANDVYETAKITELTNEVTGEKQYSATITAGGVTTDAPVVVGQDGQISISFPATTIPGVNNYYVVDSTKSEADAISPTFTFTKDGNLVIKNTVKYAPVKQELQVQVYDDDADDPSQALDTTKTGATVDFTGDSFTNFPSDVATNVDSLIKYYTDRGYLIKTKPSDEELSGKFDGDKTQTQYLKLQLVHDKATVSGEDENTPAPDTPINENDPDGVKYPSDVSKDNLVISSKNIIHYYDEAGNKILDDKVNTDDSTLTRTVTIDKVTGKVTNTSDWTGGKEYENVNTPVVNGYYVDKASASAGASTVTPADANSGRVHDGVITNETTVIYHPMGHIIPIDKSGNKIPGAETPIFTNDTKDPTKASTTNSPIIPGYHLETPSDSAITPDEPGKDRPVVYVADTQELKVQVFDLDGDTPDEPLKTDKTGATVDFTGDSFTNFPSDVATNVDSLIKYYTDRGYLIKTKPSDEELSGKFDGDKTQTQYLKLQLVHDKATVSGEDENTPAPDTPINENDPDGVKYPSDVSKDNLVISSKNIIHYYDEAGNKILDDKVNTDDSTLTRTVTIDKVTGKVTNTSDWTGGKEYENVNTPVVNGYYVDKASASAGASTVTPADANSGRVHDGVITNETTVIYHPMGHIIPIDKSGNKIPGAETPIFTNDTKDPTKASTTNSPIIPGYHLETPSDSAITPDEPGKDRPVVYVADTQELKVQVFDLDGDTPDEPLKTDKTGATVDFTGDSFTNFPSDVATNVDSLIKYYTDRGYLIKTKPSDEELSGKFDGDKTQTQYLKLQLVHDKATVSGEDENTPAPDTPINENDPDGVKYPSDVSKDNLVISSEVIIHYEGAGEKTPKNVIRTVDKTLTRTVTIDKVTGKVTNTSDWSSNTTEYESVLTPQIQGYTSDKVQVDKVSITKDNAGEAKNGKITYTFNVVYTPDKQQLILKVHDEDTQSYLGDPVIFDGYTDQEVGNSPVDKLEELKKKYLDLGYEIVEIPQLDKNYDDTPNVGGEPDKEPQVFVLKVKHRIVPVTPDDPKTPDDIIPDSNQNYPGGLTETDLSRTITRTIVVNFPSGTSQEIKQVVTYTRTATVDAVTKEVKYSAWTTKNSNWPKYVAPVVPGYTPDKDMIELTYVPADGKDVTVEINYTADPEPDEPTTPVKPGEPITPVTPTTPTTPTKPVKPTKPSKPKKPAKQTKPEVVKPVKETKGKQLYGSAQAKVDSKAAQNVVDKNKANGTNDKKLPQTNGESNWQLSLLGVGVLALALLVLKKKRDDE
>NZ_CP039266.1|WP_158181924.1|1192565_1193837_+|ISL3-family-transposase
MSSLNDYIKFTLDVEDKNIIFSDYSNENINGKIYKIYLAELIQPTCPYCRSTNLKHNGHYVSNVRFITADASKPVTIRLRKQRVLCNDCLKRSMAQSNLVNKGSYISNTSKRKILSALTEDRSMTSIAREHNVSVNTVQRVLEACSSKFYDDFDHLPEHLAFDEFKGVGKKLHFICLDGDTHKVVQILRTRFKPDILRYFYKFTPKARAMVKTVTMDLNCYYPLVARKLFPNAQIVIDRFHMVQMLTRSFNIFRVQIMKQFNKRSREYKLLKSPWKLYLMKYDKLNKTTPYYDWHFKDCLTQEHVVLDGLDCDQTLENTYWVMQDFMTAIQDNDEKKVIHLLHSKQSVGKQMHQTLLTFKHNYSGVLNGISSTYSNGCLEGVNRKIKQIERTAYGYRNFSHLLIRLEENIVKEKESSNFFFVA
>NZ_CP039266.1|WP_158181923.1|1192077_1192317_-|peptide-binding-protein
MIVGNLGAQKEKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAKNGGNVKEVMEIRLRSKLKRVLIVHYLKILYNRN
>NZ_CP039266.1|WP_057727000.1|1211690_1212569_-|YitT-family-protein
MDQLDKFNRRYNFLSKLSAAFFYSIAVAVALNFFWTPGHMYSSGITGFAQLINTVSERYLPFTLSTSMMYFLLNFPLFILAWFKIGRKFTFFTIVAVVLGSIMMHAIQPWQMHLDPLVCAIFGASINGIGTGMALKNGISTGGLDIIGIVIRQKTGISYGKFNIFINLIIIAAAGYMFGWPRALYSALTIFINGRVIDAVYTQHQKMQVMIVTQHPQHIIDGIQNRMHRGITILHDAEGAYSHIEKTVLITIIDRYDMYDIRQIVQGADPYAFMSVSEVEKVYGRFKEQEIV
>NZ_CP039266.1|WP_158181930.1|1213020_1213878_-|SEC10/PgrA-surface-exclusion-domain-containing-protein
MNFKKIAILSASVLALSTCAVSVIESPSTHVVYAAKSKLKTRIAVPKGYTADLIEDWCDSPNNKKLTRKLKRLSRRGMLSNKFYDRRKADKRKVNLANLSNRDQYELSQYALTLINSIRTQLGLPKFTYTASAQSFANDIAKAYNKDNWSDYQGHDISAINRTAKQHGLTKNDNEYEDMGGFDITTGHQYATIYQIKQNIYYNIKQAAFGGFWYHNNQESDKYNLNYYTEWNHANDLFTGDYSQEFALSLSYLIQDPTNKVNKITSSHYIHVDPENIEKKALYEK
>NZ_CP039266.1|WP_158181931.1|1213989_1214877_-|lysin
MTKTYLVDVAKYQPNSLRTYKNAGAKSAIVQVSVAKSIVAPKAKAQVKSAKANGLVPMGYFYACFGNSVSEAEAESRFAVSQAEAAGIPAGSFLGVDWESQDNNTSNGSRSNTNAILAAMDVIKKAGYKPLLYSSASLMRTKIDTARVTDKYGTCLWVASYPYSGATYSPDFRYFPSMKGVAIWQFTDNWKGLSVDGNVGFISFEPARVKITKVKHASWHAQKGVFVLGQALELHKSPHVSSPAIAKLEKGASVVYDATLQGPLRLWIRQPREKGYGYMVAKDRYGRFLGKMITK
>NZ_CP039266.1|WP_158181932.1|1214936_1215269_-|hypothetical-protein
MNYISEISTIAIIAFVSLCVCYMFFYENISKKDPQKVSDSKYKDIYEIAKLIVDDFDPTGLKPLKPEDHQQAVAKVQDQAQKDGLDVTQAVASGAVKKAVQDKQQESPKN
>NZ_CP039266.1|WP_158181933.1|1215271_1215502_-|hypothetical-protein
MNADLYAVLASGAVGGIISAIASGIVEYKKLKDSETYQAEKDEREQIEFYRQKWLEDEDQIDKLRDELRTLKDKEK
>NZ_CP039266.1|WP_158181934.1|1216028_1216421_-|hypothetical-protein
MKKVFTYARAQLERHPLHIILALVLIGLGAFLIANDSYFTWPPALQAVVNSDFFGTWAIFNGLGLLYVAFSKPWPYRANLIWLMSTAGFLGCETAMEIAHDVLGKADHTTGFLVLVLGYLILAFVIAKKD
>NZ_CP039266.1|WP_158181935.1|1216432_1219270_-|hypothetical-protein
MDLQKVTLPLLILDVEHNDQKQALAHVLNQHDAGYVQPFILNSGDDAYDVPAEDFHFRASLPDNQIIDVDNSNGDLVQKGDQNWLLNLPTGVTGVPGLVKCVVYAKDDGRVLASSQQIMYNVMPAFDVEDASHVSYVPDLDKLKANLQNLLGKAQDQVTRLSGITAGDKQAAEQALKEELDKLGKQAGDWLDGEKANVNKQIADIVKQSSGLDEAYKQAYKEEIDKLAGQTGKDYEAKLQAVIDKLNNDKQASLQAINDDWTKQKVSLQTDIAGFKDNLTKQVEAITSTVNALNTSDLPAIQSKVNSFKDALDKLNSQISAIKLDYYTKDEIDNKLDSLKAGATPDLTDLKKQVQDNTTSLQSKVGKDELTNYALKSDVTQPDLTGYATTQALTDGLSNKADKNALDAYALKSELPAMPDLSAYAKVTALENYATKQALNAYALKTDLPDLTSYAKKSDLPDISGLETQADHANDVKKINETLETYAKKSELPDISGLETKADHKADVDKLNKALDSKADKTALDAYALKKDVPASPDLSGYAKTADLAAYETSASHKADIDKLNKALEAKADISAIPALPDMSQYALKTDLKNVDLTGYLTKDDADRLLGEKANESELADYAKKTDLPPVPNLTVYAKVTDVAKALNNKADTDALREYAKTADVERVNKAATHANIVANFAMQNSQSAVYGIQVDDGPLLPKAHGHINLPLGLSDYLKKADADNEYAKKTDIPAIPDTSNFVTNDSLTDKLQNYNGGYLTNWDAAQKYETAAQVQELINGQLGNIHEEYAPRALLNDYTQTADLPKYLSDNYGLANQVGDVHPLINSIRGLTYLTSATPEYSDSHNSEADKNGVIDVNKDAPYASGPVIFPSVLNTNASTVDMLNSYSRANKNYILSTWITTKNKDGSQNTDLRYSIGGNELALMSDISALSDRVKALEQKLNK
>NZ_CP039266.1|WP_158181936.1|1219270_1219474_-|hypothetical-protein
MNDTNETNEIFASDAMQIIKVYMQQKAALQSRVLELEKENENLKHELQELAEKHDKNVIKLDQKEGK
>NZ_CP039266.1|WP_158181937.1|1219485_1221744_-|hypothetical-protein
MRFYVYDQASNLTALITKANSAKLEQNLGQYDALAVEFPLGEANAELLKDAYYLGIPVYGQYELFRVQNTVLTSLAIQVTGLEAASDDLQTQGYVEAISDDNCYLSSALDKVFKGSMWEYELLAPDSKKTLVFNTGSRKDLLEQIRSNWGIETEFRYEMSGSKIKRRVCYVKSKIGGVFPTRLVRGQNVLSWQYTSDYSQIYTACLALGSKMSETLQQPIPGSTETTETTREWTVDLTQAEWSKAAGNPIDKPAGQNYVELPDLTAKFGWQDENGTRHPRMAVKTFSNDKDPQTLLTDAYLWLIDQASPKLAVTASVSQVGEIQLGDDCTLIDYSQPKMAIKERAIKISRDLLNNHNTVVQIGQYTIKTTAQRIQEAKKELKQSAKDAIKDARIKAAKDTALKIKPIKLKQAAHEKALKLHEGKLKDHEGRIKGLKDLGDKLTKGFNDNAAKLASQGDKLKSLQDKLDSSGAGTGTGAMTDTTGRFAMHFDQNTPNKVLTADFNYDSGAKLGFNGQQFTLTNGAGGTVASLNDTGLLTAAEIGTDKSPIGKVYSGEFDPVAVLPNGSVQDDPDNSASFQATHLELNKNVGTYNKQAFLTSDALTLSYPLADGTTGSYGNQKIVLELNNDAVPSVPQLLISQGKNKAVLTPTGLYFNDKNILELTGGKTTLPDNLLTSDNLGGALNDLSSAMINGSKILTEQNLSDMFDDAEQKGAGSYNPLIEGLLNLVISQDFMDFICRELDARGYIKDSH
>NZ_CP039266.1|WP_158181938.1|1221743_1222562_-|hypothetical-protein
MLYYQFTDLQPTDRGQPGGAPDEALVLPINGQFKTIEEFLPDYQTLQVTGRELVPYSLSTTHVDGLDGDILKNADRKSRQIKITYLIQAPDSLSYRADFNKLNEILNNKQFEFYFMDDISYVYTGTVSAISDPTAGSNTGVGSFTITCPDPYKYAKRPATITFTKSTKIAGDDNPFFPVVPDEIDLTAPEGCSHLELSNSHGQKIKLSGHLSSKEIKMWPNQNPANISIGGDPNLSVIDIDSDYENWAIWQSDTITCSENVPVSITYRKKLI

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Crispr_ID: NZ_CP039266_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP039266_4

1275321-1276814

Orphan

I-B,III-A,III-B

Consensus_repeat	Method
GGATCACCTCCACATACGTGGAGAATAC	CRISPRCasFinder
GGATCACCTCCACATACGTGGAGAATAC	CRT
GGATCACCTCCACATACGTGGAGAATA	PILER-CR
AGGATCACCTCCACATACGTGGAGAATAC	PILER-CR

24 spacers

The CRISPR arrays of NZ_CP039266_4

>merge|NZ_CP039266|4|1275321-1276814|CRISPRCasFinder,CRT,PILER-CR,PILER-CR
AAGATGCCTCCACGTACGTGGAGAATACCACGGTATTTCGATACCAATATGTCGAAGACCGGGGATCACCTCCACATACGTGGAGAATACATTCTATGCGGTGTTTTTAACATCAGAGTACAAGGATCACCTCCACATACGTGGAGAATACAATGGCAAAAAGGATATGGCACGATCGTTGTTAGGATCACCTCCACATACGTGGAGAATACAACAAACTTTTTACCTTCATAGTGCCCGGTATAGGATCACCTCCACATACGTGGAGAATACTTTAACATTGATGTAGACACCAGGTCTTACTTTAGGATCACCTCCACATACGTGGAGAATACCTTCAGTTCTTCGTCGGTCAAACGTTTGATTCGGGATCACCTCCACATACGTGGAGAATACTAAAGGTTCAATTTTTGAACGGGTAAAGGGCTAGGATCACCTCCACATACGTGGAGAATACTCACCGATATTGTTCCAAGAGCCGTTCTTATTAGGATCACCTCCACATACGTGGAGAATACTCACCGATATTGTTCCAAGAGCCGTTCTTATTAGGATCACCTCCACATACGTGGAGAATACGAACCATTTTGAATGTTGGCAATATGTGTAGCAGGATCACCTCCACATACGTGGAGAATAGCCATCTTTTGATAACAAAAACTTAGCAAGTGCGGGATCACCTCCACATACGTGGAGAATACTTTCATGTTGGACTTAGTCCTGTAGGATAGTAAGGATCACCTCCACATACGTGGAGAATACAAGATGATAATTCTGAGTTTGAAAGCAGCGACAGGATCACCTCCACATACGTGGAGAATACGCGGTCAACTTCAAGTAGCAGACTACAAGAAGAGGATCACCTCCACATACGTGGAGAATACTATAAATTAAGTATAATTACAAAAATCCAGTAAGGATCACCTCCACATACGTGGAGAATACATAAGATTGAGAATGCATCATTGTGGCAGCGTAGGATCACCTCCACATACGTGGAGAATACAGAAGGCAAAACTAGCATGATCACTGTTAGATAGGATCACCTCCACATACGTGGAGAATACAAACTTTGTTGCAAAGCTGGAAGAGATGGTTAGGGATCACCTCCACATACGTGGAGAATACACGGTATTTCGATACCAATATGTCGAAGACCGGGGATCACCTCCACATACGTGGAGAATACCAGTAGTGTCGTCAGTAATGTCGACTATAGATGGGATCACCTCCACATACGTGGAGAATACAGAAACCAATTATTCCATATACAGGTGACATCAGGATCACCTCCACATACGTGGAGAATACTGTAGCAATTCATAACGCAACAATTGACAGCTAGGATCACCTCCACATACGTGGAGAATACTAGAAGCTGGCAGCATTGAATTCGTAGTTCAGAGGATCACCTCCACATACGTGGAGAATACCCATTTTTAGGCTTGATTGTAGCCCCAAATTCGGGATCACCTCCACATACGTGGAGAATAC

>NZ_CP039266|4|4|1275321-1276814|CRISPRCasFinder
AAGATGCCTCCACGTACGTGGAGAATAC	CACGGTATTTCGATACCAATATGTCGAAGACCGG
GGATCACCTCCACATACGTGGAGAATAC	ATTCTATGCGGTGTTTTTAACATCAGAGTACAA
GGATCACCTCCACATACGTGGAGAATAC	AATGGCAAAAAGGATATGGCACGATCGTTGTTA
GGATCACCTCCACATACGTGGAGAATAC	AACAAACTTTTTACCTTCATAGTGCCCGGTATA
GGATCACCTCCACATACGTGGAGAATAC	TTTAACATTGATGTAGACACCAGGTCTTACTTTA
GGATCACCTCCACATACGTGGAGAATAC	CTTCAGTTCTTCGTCGGTCAAACGTTTGATTCG
GGATCACCTCCACATACGTGGAGAATAC	TAAAGGTTCAATTTTTGAACGGGTAAAGGGCTA
GGATCACCTCCACATACGTGGAGAATAC	TCACCGATATTGTTCCAAGAGCCGTTCTTATTA
GGATCACCTCCACATACGTGGAGAATAC	TCACCGATATTGTTCCAAGAGCCGTTCTTATTA
GGATCACCTCCACATACGTGGAGAATAC	GAACCATTTTGAATGTTGGCAATATGTGTAGCA
GGATCACCTCCACATACGTGGAGAATAG	CCATCTTTTGATAACAAAAACTTAGCAAGTGCG
GGATCACCTCCACATACGTGGAGAATAC	TTTCATGTTGGACTTAGTCCTGTAGGATAGTAA
GGATCACCTCCACATACGTGGAGAATAC	AAGATGATAATTCTGAGTTTGAAAGCAGCGACA
GGATCACCTCCACATACGTGGAGAATAC	GCGGTCAACTTCAAGTAGCAGACTACAAGAAGA
GGATCACCTCCACATACGTGGAGAATAC	TATAAATTAAGTATAATTACAAAAATCCAGTAA
GGATCACCTCCACATACGTGGAGAATAC	ATAAGATTGAGAATGCATCATTGTGGCAGCGTA
GGATCACCTCCACATACGTGGAGAATAC	AGAAGGCAAAACTAGCATGATCACTGTTAGATA
GGATCACCTCCACATACGTGGAGAATAC	AAACTTTGTTGCAAAGCTGGAAGAGATGGTTAG
GGATCACCTCCACATACGTGGAGAATAC	ACGGTATTTCGATACCAATATGTCGAAGACCGG
GGATCACCTCCACATACGTGGAGAATAC	CAGTAGTGTCGTCAGTAATGTCGACTATAGATG
GGATCACCTCCACATACGTGGAGAATAC	AGAAACCAATTATTCCATATACAGGTGACATCA
GGATCACCTCCACATACGTGGAGAATAC	TGTAGCAATTCATAACGCAACAATTGACAGCTA
GGATCACCTCCACATACGTGGAGAATAC	TAGAAGCTGGCAGCATTGAATTCGTAGTTCAGA
GGATCACCTCCACATACGTGGAGAATAC	CCATTTTTAGGCTTGATTGTAGCCCCAAATTCG
GGATCACCTCCACATACGTGGAGAATAC

>NZ_CP039266|4|4|1275321-1276814|CRT
AAGATGCCTCCACGTACGTGGAGAATAC	CACGGTATTTCGATACCAATATGTCGAAGACCGG
GGATCACCTCCACATACGTGGAGAATAC	ATTCTATGCGGTGTTTTTAACATCAGAGTACAA
GGATCACCTCCACATACGTGGAGAATAC	AATGGCAAAAAGGATATGGCACGATCGTTGTTA
GGATCACCTCCACATACGTGGAGAATAC	AACAAACTTTTTACCTTCATAGTGCCCGGTATA
GGATCACCTCCACATACGTGGAGAATAC	TTTAACATTGATGTAGACACCAGGTCTTACTTTA
GGATCACCTCCACATACGTGGAGAATAC	CTTCAGTTCTTCGTCGGTCAAACGTTTGATTCG
GGATCACCTCCACATACGTGGAGAATAC	TAAAGGTTCAATTTTTGAACGGGTAAAGGGCTA
GGATCACCTCCACATACGTGGAGAATAC	TCACCGATATTGTTCCAAGAGCCGTTCTTATTA
GGATCACCTCCACATACGTGGAGAATAC	TCACCGATATTGTTCCAAGAGCCGTTCTTATTA
GGATCACCTCCACATACGTGGAGAATAC	GAACCATTTTGAATGTTGGCAATATGTGTAGCA
GGATCACCTCCACATACGTGGAGAATAG	CCATCTTTTGATAACAAAAACTTAGCAAGTGCG
GGATCACCTCCACATACGTGGAGAATAC	TTTCATGTTGGACTTAGTCCTGTAGGATAGTAA
GGATCACCTCCACATACGTGGAGAATAC	AAGATGATAATTCTGAGTTTGAAAGCAGCGACA
GGATCACCTCCACATACGTGGAGAATAC	GCGGTCAACTTCAAGTAGCAGACTACAAGAAGA
GGATCACCTCCACATACGTGGAGAATAC	TATAAATTAAGTATAATTACAAAAATCCAGTAA
GGATCACCTCCACATACGTGGAGAATAC	ATAAGATTGAGAATGCATCATTGTGGCAGCGTA
GGATCACCTCCACATACGTGGAGAATAC	AGAAGGCAAAACTAGCATGATCACTGTTAGATA
GGATCACCTCCACATACGTGGAGAATAC	AAACTTTGTTGCAAAGCTGGAAGAGATGGTTAG
GGATCACCTCCACATACGTGGAGAATAC	ACGGTATTTCGATACCAATATGTCGAAGACCGG
GGATCACCTCCACATACGTGGAGAATAC	CAGTAGTGTCGTCAGTAATGTCGACTATAGATG
GGATCACCTCCACATACGTGGAGAATAC	AGAAACCAATTATTCCATATACAGGTGACATCA
GGATCACCTCCACATACGTGGAGAATAC	TGTAGCAATTCATAACGCAACAATTGACAGCTA
GGATCACCTCCACATACGTGGAGAATAC	TAGAAGCTGGCAGCATTGAATTCGTAGTTCAGA
GGATCACCTCCACATACGTGGAGAATAC	CCATTTTTAGGCTTGATTGTAGCCCCAAATTCG
GGATCACCTCCACATACGTGGAGAATAC

>NZ_CP039266|4|4|1275383-1276813|PILER-CR
GGATCACCTCCACATACGTGGAGAATA	CATTCTATGCGGTGTTTTTAACATCAGAGTACAA
GGATCACCTCCACATACGTGGAGAATA	CAATGGCAAAAAGGATATGGCACGATCGTTGTTA
GGATCACCTCCACATACGTGGAGAATA	CAACAAACTTTTTACCTTCATAGTGCCCGGTATA
GGATCACCTCCACATACGTGGAGAATA	CTTTAACATTGATGTAGACACCAGGTCTTACTTTA
GGATCACCTCCACATACGTGGAGAATA	CCTTCAGTTCTTCGTCGGTCAAACGTTTGATTCG
GGATCACCTCCACATACGTGGAGAATA	CTAAAGGTTCAATTTTTGAACGGGTAAAGGGCTA
GGATCACCTCCACATACGTGGAGAATA	CTCACCGATATTGTTCCAAGAGCCGTTCTTATTA
GGATCACCTCCACATACGTGGAGAATA	CTCACCGATATTGTTCCAAGAGCCGTTCTTATTA
GGATCACCTCCACATACGTGGAGAATA	CGAACCATTTTGAATGTTGGCAATATGTGTAGCA
GGATCACCTCCACATACGTGGAGAATA	GCCATCTTTTGATAACAAAAACTTAGCAAGTGCG
GGATCACCTCCACATACGTGGAGAATA	CTTTCATGTTGGACTTAGTCCTGTAGGATAGTAA
GGATCACCTCCACATACGTGGAGAATA	CAAGATGATAATTCTGAGTTTGAAAGCAGCGACA
GGATCACCTCCACATACGTGGAGAATA	CGCGGTCAACTTCAAGTAGCAGACTACAAGAAGA
GGATCACCTCCACATACGTGGAGAATA	CTATAAATTAAGTATAATTACAAAAATCCAGTAA
GGATCACCTCCACATACGTGGAGAATA	CATAAGATTGAGAATGCATCATTGTGGCAGCGTA
GGATCACCTCCACATACGTGGAGAATA	CAGAAGGCAAAACTAGCATGATCACTGTTAGATA
GGATCACCTCCACATACGTGGAGAATA	CAAACTTTGTTGCAAAGCTGGAAGAGATGGTTAG
GGATCACCTCCACATACGTGGAGAATA	CACGGTATTTCGATACCAATATGTCGAAGACCGG
GGATCACCTCCACATACGTGGAGAATA	CCAGTAGTGTCGTCAGTAATGTCGACTATAGATG
GGATCACCTCCACATACGTGGAGAATA	CAGAAACCAATTATTCCATATACAGGTGACATCAGGATCACCTCCACATACGTGGAGAATACTGTAGCAATTCATAACGCAACAATTGACAGCTAGGATCACCTCCACATACGTGGAGAATACTAGAAGCTGGCAGCATTGAATTCGTAGTTCAGAGGATCACCTCCACATACGTGGAGAATACCCATTTTTAGGCTTGATTGTAGCCCCAAATTCG
	TGTAGCAATTCATAACGCAACAATTGACAGCT
AGGATCACCTCCACATACGTGGAGAATAC	TAGAAGCTGGCAGCATTGAATTCGTAGTTCAG
AGGATCACCTCCACATACGTGGAGAATAC	CCATTTTTAGGCTTGATTGTAGCCCCAAATTC
GGGATCACCTCCACATACGTGGAGAATA

>NZ_CP039266|4|5|1276603-1276814|PILER-CR
	CATTCTATGCGGTGTTTTTAACATCAGAGTACAA
GGATCACCTCCACATACGTGGAGAATA	CAATGGCAAAAAGGATATGGCACGATCGTTGTTA
GGATCACCTCCACATACGTGGAGAATA	CAACAAACTTTTTACCTTCATAGTGCCCGGTATA
GGATCACCTCCACATACGTGGAGAATA	CTTTAACATTGATGTAGACACCAGGTCTTACTTTA
GGATCACCTCCACATACGTGGAGAATA	CCTTCAGTTCTTCGTCGGTCAAACGTTTGATTCG
GGATCACCTCCACATACGTGGAGAATA	CTAAAGGTTCAATTTTTGAACGGGTAAAGGGCTA
GGATCACCTCCACATACGTGGAGAATA	CTCACCGATATTGTTCCAAGAGCCGTTCTTATTA
GGATCACCTCCACATACGTGGAGAATA	CTCACCGATATTGTTCCAAGAGCCGTTCTTATTA
GGATCACCTCCACATACGTGGAGAATA	CGAACCATTTTGAATGTTGGCAATATGTGTAGCA
GGATCACCTCCACATACGTGGAGAATA	GCCATCTTTTGATAACAAAAACTTAGCAAGTGCG
GGATCACCTCCACATACGTGGAGAATA	CTTTCATGTTGGACTTAGTCCTGTAGGATAGTAA
GGATCACCTCCACATACGTGGAGAATA	CAAGATGATAATTCTGAGTTTGAAAGCAGCGACA
GGATCACCTCCACATACGTGGAGAATA	CGCGGTCAACTTCAAGTAGCAGACTACAAGAAGA
GGATCACCTCCACATACGTGGAGAATA	CTATAAATTAAGTATAATTACAAAAATCCAGTAA
GGATCACCTCCACATACGTGGAGAATA	CATAAGATTGAGAATGCATCATTGTGGCAGCGTA
GGATCACCTCCACATACGTGGAGAATA	CAGAAGGCAAAACTAGCATGATCACTGTTAGATA
GGATCACCTCCACATACGTGGAGAATA	CAAACTTTGTTGCAAAGCTGGAAGAGATGGTTAG
GGATCACCTCCACATACGTGGAGAATA	CACGGTATTTCGATACCAATATGTCGAAGACCGG
GGATCACCTCCACATACGTGGAGAATA	CCAGTAGTGTCGTCAGTAATGTCGACTATAGATG
GGATCACCTCCACATACGTGGAGAATA	CAGAAACCAATTATTCCATATACAGGTGACATCAGGATCACCTCCACATACGTGGAGAATACTGTAGCAATTCATAACGCAACAATTGACAGCTAGGATCACCTCCACATACGTGGAGAATACTAGAAGCTGGCAGCATTGAATTCGTAGTTCAGAGGATCACCTCCACATACGTGGAGAATACCCATTTTTAGGCTTGATTGTAGCCCCAAATTCG
	TGTAGCAATTCATAACGCAACAATTGACAGCT
AGGATCACCTCCACATACGTGGAGAATAC	TAGAAGCTGGCAGCATTGAATTCGTAGTTCAG
AGGATCACCTCCACATACGTGGAGAATAC	CCATTTTTAGGCTTGATTGTAGCCCCAAATTC
GGGATCACCTCCACATACGTGGAGAATAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP039266.1\|WP_158181973.1\|1269112_1271386_+\|HAD-IC-family-P-type-ATPase	unknown	unknown	gnl\|CDD\|319771
NZ_CP039266.1\|WP_005719232.1\|1262273_1262822_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039266.1\|WP_100733361.1\|1287943_1288993_-\|heat-inducible-transcriptional-repressor-HrcA	unknown	unknown	gnl\|CDD\|234621
NZ_CP039266.1\|WP_005719254.1\|1284242_1285394_-\|molecular-chaperone-DnaJ	unknown	unknown	gnl\|CDD\|237653
NZ_CP039266.1\|WP_089146778.1\|1266832_1268062_-\|arginine-deiminase	unknown	unknown	gnl\|CDD\|234949
NZ_CP039266.1\|WP_158181971.1\|1262911_1263529_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|176102
NZ_CP039266.1\|WP_100733360.1\|1289130_1290066_-\|riboflavin-biosynthesis-protein-RibF	unknown	unknown	gnl\|CDD\|235536
NZ_CP039266.1\|WP_158182214.1\|1273712_1275032_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|180907
NZ_CP039266.1\|WP_013086469.1\|1264977_1265514_-\|citrate-lyase-holo-[acyl-carrier-protein]-synthase	unknown	unknown	gnl\|CDD\|377135
NZ_CP039266.1\|WP_158181975.1\|1281781_1283620_-\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
NZ_CP039266.1\|WP_057726509.1\|1287346_1287931_-\|nucleotide-exchange-factor-GrpE	unknown	unknown	gnl\|CDD\|237631
NZ_CP039266.1\|WP_158182213.1\|1271785_1272301_-\|BAX-inhibitor-(BI)-1/YccA-family-protein	unknown	unknown	gnl\|CDD\|198414
NZ_CP039266.1\|WP_005722136.1\|1281092_1281779_-\|class-A-sortase	unknown	unknown	gnl\|CDD\|320680
NZ_CP039266.1\|WP_098043795.1\|1265527_1266430_-\|peptide-transporter	unknown	unknown	gnl\|CDD\|179366
NZ_CP039266.1\|WP_013086488.1\|1285476_1287330_-\|molecular-chaperone-DnaK	unknown	unknown	gnl\|CDD\|234715
NZ_CP039266.1\|WP_013086487.1\|1283727_1284183_+\|NUDIX-domain-containing-protein	unknown	unknown	gnl\|CDD\|239520
NZ_CP039266.1\|WP_158181972.1\|1263695_1264862_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|226925
NZ_CP039266.1\|WP_158181974.1\|1278695_1280969_-\|single-stranded-DNA-specific-exonuclease-RecJ	unknown	unknown	gnl\|CDD\|273193
NZ_CP039266.1\|WP_057726506.1\|1268135_1268984_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_CP039266.1\|WP_065989775.1\|1278063_1278591_-\|adenine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|235028

Protein	Function_ID	Function_description	E-value
NZ_CP039266.1\|WP_158181973.1\|1269112_1271386_+\|HAD-IC-family-P-type-ATPase	gnl\|CDD\|319771	cd02076, P-type_ATPase_H, plant and fungal plasma membrane H(+)-ATPases, and related bacterial and archaeal putative H(+)-ATPases. This subfamily includes eukaryotic plasma membrane H(+)-ATPase which transports H(+) from the cytosol to the extracellular space, thus energizing the plasma membrane for the uptake of ions and nutrients, and is expressed in plants and fungi. This H(+)-ATPase consists of four domains: a transmembrane domain and three cytosolic domains: nucleotide-binding domain, phosphorylation domain and actuator domain, and belongs to the P-type ATPase type III subfamily. This subfamily also includes the putative P-type H(+)-ATPase, MJ1226p of the anaerobic hyperthermophilic archaea Methanococcus jannaschii. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_CP039266.1\|WP_100733361.1\|1287943_1288993_-\|heat-inducible-transcriptional-repressor-HrcA	gnl\|CDD\|234621	PRK00082, hrcA, heat-inducible transcription repressor; Provisional.	8.9681e-133
NZ_CP039266.1\|WP_005719254.1\|1284242_1285394_-\|molecular-chaperone-DnaJ	gnl\|CDD\|237653	PRK14276, PRK14276, chaperone protein DnaJ; Provisional.	0
NZ_CP039266.1\|WP_089146778.1\|1266832_1268062_-\|arginine-deiminase	gnl\|CDD\|234949	PRK01388, PRK01388, arginine deiminase; Provisional.	0
NZ_CP039266.1\|WP_158181971.1\|1262911_1263529_-\|transcriptional-regulator	gnl\|CDD\|176102	cd05466, PBP2_LTTR_substrate, The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily. This model and hierarchy represent the the substrate-binding domain of the LysR-type transcriptional regulators that form the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, oxidative stress responses, nodule formation of nitrogen-fixing bacteria, synthesis of virulence factors, toxin production, attachment and secretion, to name a few. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the substrate-binding domains from ionotropic glutamate receptors, LysR-like transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	2.25245e-10
NZ_CP039266.1\|WP_100733360.1\|1289130_1290066_-\|riboflavin-biosynthesis-protein-RibF	gnl\|CDD\|235536	PRK05627, PRK05627, bifunctional riboflavin kinase/FAD synthetase.	2.34696e-118
NZ_CP039266.1\|WP_158182214.1\|1273712_1275032_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|180907	PRK07251, PRK07251, FAD-containing oxidoreductase.	2.01873e-173
NZ_CP039266.1\|WP_013086469.1\|1264977_1265514_-\|citrate-lyase-holo-[acyl-carrier-protein]-synthase	gnl\|CDD\|377135	pfam03802, CitX, Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase.	1.22099e-67
NZ_CP039266.1\|WP_158181975.1\|1281781_1283620_-\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NZ_CP039266.1\|WP_057726509.1\|1287346_1287931_-\|nucleotide-exchange-factor-GrpE	gnl\|CDD\|237631	PRK14162, PRK14162, heat shock protein GrpE; Provisional.	1.02882e-89
NZ_CP039266.1\|WP_158182213.1\|1271785_1272301_-\|BAX-inhibitor-(BI)-1/YccA-family-protein	gnl\|CDD\|198414	cd10432, BI-1-like_bacterial, Bacterial BAX inhibitor (BI)-1/YccA-like proteins. This family is comprised of bacterial relatives of the mammalian members of the BAX inhibitor (BI)-1 like family of small transmembrane proteins, which have been shown to have an antiapoptotic effect either by stimulating the antiapoptotic function of Bcl-2, a well-characterized oncogene, or by inhibiting the proapoptotic effect of Bax, another member of the Bcl-2 family. In plants, BI-1 like proteins play a role in pathogen resistance. A characterized prokaryotic member, Escherichia coli YccA, has been shown to interact with ATP-dependent protease FtsH, which degrades abnormal membrane proteins as part of a quality control mechanism to keep the integrity of biological membranes.	2.59867e-25
NZ_CP039266.1\|WP_005722136.1\|1281092_1281779_-\|class-A-sortase	gnl\|CDD\|320680	cd06165, Sortase_A, Sortase domain found in class A sortases. Class A sortases are membrane-bound cysteine transpeptidases distributed in Gram-positive bacteria (mainly present in Firmicutes). They perform a housekeeping role in the cell as members of this group are capable of anchoring a large number of functionally distinct surface proteins containing a cell wall sorting signal to an amino group located on the bacterial cell wall. They do so by catalyzing a transpeptidation reaction in which the surface protein substrate is cleaved at a conserved cell wall-sorting signal (Class A sortases recognize a canonical LPXTG motif, X can be any amino acid), and covalently linked to peptidoglycan for display on the bacterial surface. The prototypical sortase A protein from Staphylococcus aureus (named Sa-SrtA) cleaves the amide bond between threonine and glycine residues of the canonical LPXTG motif in a wide range of protein substrates with diverse functions that can promote bacterial adhesion, nutrient acquisition, host cell invasion, and immune evasion. Next, it catalyzes a transpeptidation reaction by which the proteins are covalently linked to the peptidoglycan precursor lipid II. SrtA is therefore affects the ability of a pathogen to establish successful infection. SrtA contains an N-terminal hydrophobic segment, a linker region and an extra-cellular C-terminal catalytic domain. The hydrophobic segment functions as both a signal peptide for secretion and a stop-transfer signal for membrane anchoring. The catalytic domain contains the catalytic TLXTC signature sequence where X is usually a valine, isoleucine or a threonine. The gene encoding SrtA is generally not located in the same gene cluster as its substrates while the gene encoding SrtB is usually clustered in the same locus as its substrate.	8.99768e-57
NZ_CP039266.1\|WP_098043795.1\|1265527_1266430_-\|peptide-transporter	gnl\|CDD\|179366	PRK02102, PRK02102, ornithine carbamoyltransferase; Validated.	3.00692e-96
NZ_CP039266.1\|WP_013086488.1\|1285476_1287330_-\|molecular-chaperone-DnaK	gnl\|CDD\|234715	PRK00290, dnaK, molecular chaperone DnaK; Provisional.	0
NZ_CP039266.1\|WP_013086487.1\|1283727_1284183_+\|NUDIX-domain-containing-protein	gnl\|CDD\|239520	cd03428, Ap4A_hydrolase_human_like, Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Ap4A hydrolases are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant enzymes fall into one subfamily and fungi/animals/archaea enzymes, represented by this subfamily, fall into another. Bacterial enzymes are found in both subfamilies. Ap4A is a potential by-product of aminoacyl tRNA synthesis, and accumulation of Ap4A has been implicated in a range of biological events, such as DNA replication, cellular differentiation, heat shock, metabolic stress, and apoptosis. Ap4A hydrolase cleaves Ap4A asymmetrically into ATP and AMP. It is important in the invasive properties of bacteria and thus presents a potential target for inhibition of such invasive bacteria. Besides the signature nudix motif (G[X5]E[X7]REUXEEXGU, where U is Ile, Leu, or Val) that functions as a metal binding and catalytic site, and a required divalent cation, Ap4A hydrolase is structurally similar to the other members of the nudix superfamily with some degree of variation. Several regions in the sequences are poorly defined and substrate and metal binding sites are only predicted based on kinetic studies.	2.26473e-37
NZ_CP039266.1\|WP_158181972.1\|1263695_1264862_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|226925	COG4552, Eis, Predicted acetyltransferase involved in intracellular survival and related acetyltransferases [General function prediction only].	3.56717e-43
NZ_CP039266.1\|WP_158181974.1\|1278695_1280969_-\|single-stranded-DNA-specific-exonuclease-RecJ	gnl\|CDD\|273193	TIGR00644, recJ, single-stranded-DNA-specific exonuclease RecJ. All proteins in this family are 5'-3' single-strand DNA exonucleases. These proteins are used in some aspects of mismatch repair, recombination, and recombinational repair. [DNA metabolism, DNA replication, recombination, and repair].	5.79368e-173
NZ_CP039266.1\|WP_057726506.1\|1268135_1268984_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	1.83645e-50
NZ_CP039266.1\|WP_065989775.1\|1278063_1278591_-\|adenine-phosphoribosyltransferase	gnl\|CDD\|235028	PRK02304, PRK02304, adenine phosphoribosyltransferase; Provisional.	5.64594e-96

>NZ_CP039266.1|WP_158182214.1|1273712_1275032_-|FAD-dependent-oxidoreductase
MKTVKNIIIGFGKGGKTLAKFLAKKGEKVLVIEKSNQMYGGTCINIACLPSKRLIIEAGNGVDFVDAVNGKNKMTSMLRGKNYHMLADEKTVTVLDGTAKFTGDHEVAVTLTNGQVEEYRGERIFINTGAVPVMLPIPGLAESSAILDSTAAMAQAELPKKLVIIGAGYIGLEFASMFAEYSSEVTVLDLHDNFLPREDDDIAAEIKRDLELNGVKFELGVKITKVDDHTIYYEKNGESLTITADRILVATGRKPNTENLGLKNTKIKLTERGAIVVDDYLRTNVKNVWAIGDVKGGLQFTYISLDDFRIIKDQLYGDAQRKVSDRINVPYSVFITPALSRVGLNEKEAKAQKVEYELKKLPVAAIPKAQVLKDPRGLFKALINPANNQILGVTLYGAESYELINQISLAMKMKIPAHVLRDQIYTHPTMSESFNDLFK
>NZ_CP039266.1|WP_158182213.1|1271785_1272301_-|BAX-inhibitor-(BI)-1/YccA-family-protein
MALAVFISATSAYLTMTFFARSFASFIAAHQWEVWLLILLPIVYGVTFAFLTEAYSGHNVASAFVASATVFVIMAIIGTVTKKDLSRIGSYASAALIGLIVAMVINLFLHNPIIDYIFSTISVIIFTILTAWDAQRMKNIYLRYGDDISTNGLAVLGALQLYLDFILIQMK
>NZ_CP039266.1|WP_158181973.1|1269112_1271386_+|HAD-IC-family-P-type-ATPase
MSDKFHGLTQAEADKRLKEDGLNEVPEPEYNFFKEFLSKLWNLSAWILEAALILECILGKWVQSSFVLLMLLFAAFNGASKKKQSRRVLNNISHKLTPTVSVERDGKWIKLDSKQLVKGDLISLKRGDVLAADVKIVDGNLACDESSITGESKPVKKAIDDTAFAGTTVVEGDGLAVVTATGKDSRSGKTINLINNSAAPGHLQQLLTKIIYYLCLLDGVLTLVIIIASFFKGGNFNTFINMLPFLAMMFIASIPVAMPSTFALSNSFEATRLSKEGVLTSDLTGIQDAANLNLLLLDKTGTITENKTAVAAWTDLSDLPDKDVLALAGAATDKRNAGIIDTAIDEYLVENNIPVMNAENFTPFTSDTGYSMADVAGHNVKLGSFKQLSLIDKHADEEISGINFKAGRSVAVLIDDKLAGVFILQDKVRTDSKAALAELKKRGVRPIMLTGDNQKTAAAVAEQVDLTGEVISIHDFNENTDINDLAGIADVLPEDKLKMVKLFQEKGYIVGMTGDGVNDAPALKQAEVGIAVSNAADVAKRSGKMVLLDDGLGSIVKILDAGHRVYQRMTTWSLTKLARTAELTMLLTFGYLFFDYIPMALNAMVIYTIMNNMVTMMIGTDRTHITYKPENWNMAKLAKIAFSLAAGWTLIGIGFVWFLNTHGWSHGAVSTMVYVYLVLSAMLIVLITRTRKYFWLDYPSKLVGSVQIADVLLTFILALCGWAMVQISIQNLAITVLVALIAAVVIDLVYQPVMKNR
>NZ_CP039266.1|WP_057726506.1|1268135_1268984_-|LysR-family-transcriptional-regulator
MNLKQLRYFLVVAEEKQITAAAKRLYIAQPPLSYQLKQLEKELGAQLFKRTAHGIELTDVGQIFQSYANEIISLAQNAENQVHKTISGELGTIAIGMASSSTGLIPMNSFNELRKYYPEISFDIYEDNTYGILDKLEKKTIDLGIVRTPYNQTGLNTKTLTTEKMMAISVDPDFQQKKELRIKDLADQPLIIYRRFEDIFNQTFAHHGLKPFYAVKCDDSRTAITWAKRKMGVALVPESIATTYAQENMIAIKHANWITHLQLVWRKDHQVTPLMKKIIDAI
>NZ_CP039266.1|WP_089146778.1|1266832_1268062_-|arginine-deiminase
MSSPIHVYSEIGKLKTVMLHRPGKELENLAPDILHRMLIDDIPYLKIAQEEHDAFAHVLRQQGIKVLYLEDLLAESLTDEKVRRAFLDQLLDESSIKKQDPLHQLLLNYLQELPTKEMVKTVIAGIRKSAIHNSTPSLADLAEDPDYPFYLDPMPNVYFTRDQQAAIGSGMTINRMTFRARRRESLFMETILKNHPDFKNATIPVWRDRYHHGRLEGGDELVLNNHVLAVGISQRTSATAITDLAHNLFGHSSYDTILAIKIPHNHAMMHLDTVFTMINYDQFTVHPFILDKAGKIDIYVLQPDDHNGVKITEKNDLVQVLKENLHLSELDLIPTGGGDPIAAPREQWNDGSNTLAIAPGEVVTYDRNYVSNDLLRKHGIIVHEIRSSELSRGRGGPRCMSCPLVREDL
>NZ_CP039266.1|WP_098043795.1|1265527_1266430_-|peptide-transporter
MGDGRDNVADSLLVCGSMLGVNVHIVTPKPLFTHPDVQKIAQNFAQDSGSKNLITDDIAQGVKGANVVYTDVWVSMGENDWSERIKLLKPYTVTMKMMQMTGTPDDQLIFMHCLPAFHDRTTQVGEEIYEKYGLNEMEVTDEVFNSKYAWQFTEAENRLHSIKAVMAATLGNLFIPIACGGGGIPVIVKDGHLRGVAGVIDKDFSAAKMAEDINADELVILTTVDHAFLNYGKENQQAIGKIKVEQLKQYLAEGYFAAGSMKPKIEAAIEFVEKTGNLAIITSLSNANKLADGVGTIVYN
>NZ_CP039266.1|WP_013086469.1|1264977_1265514_-|citrate-lyase-holo-[acyl-carrier-protein]-synthase
MNIFNEGKKQDIAQVLAAKDRRVAVQHKIFNKYPNQTLVDIKMNIPGPIKNNRYLTKMFMFGINELENAWTNLGYHFKLVTQLNDDSGCENFYVLSLSIEKVKRSTIDFEDQTSLGRLFDADVLVKNKQAAISRRDLGRQPRKCFLCDRPAKECARSRRHSVEQMQAFISQLYQEYVA
>NZ_CP039266.1|WP_158181972.1|1263695_1264862_-|GNAT-family-N-acetyltransferase
MKLKKNKNNLKQITALIQYAFLKNNDLTKDENFMSRYDHSTGYGYFDKEKLASYIMVNRFKSDVFGHHLPMAGIGYVASYPEYRGKGHISQLMKEILHDLHRQDIPFANLAPFSESFYRQYGFSNSIYQKEYRFDGSALRSFKLPRSGHIVRGKWDNLAVQNGVIQLYERQLHTDDERNTVVREAWWWNRLDSYYHHRNVAVYFDADERPISYLIYRIRDNTFLADEMYAITPQGLLSMFGFMGSHAGSVKQFKMSVPEKSLRAELFPEQNELQVDLRPYMMSRIIDFEKVLACMRPMQEGDFNLEVNSDEQCPWNIGVWQLSNHGRKVAVERKEDALVDFSGSITAWTQVLLGRLTMNAAVKLGLITDYRIKKLDFVKGDVSFYDYF
>NZ_CP039266.1|WP_158181971.1|1262911_1263529_-|transcriptional-regulator
MKNKMTELKIAYFDQLGRKELDQAVQHFVLKHPNVDVKLLVTSHDGAFAKLNEDEADIAINDLRDENLNFDETELTQAGVMAILPKGMYPNGIQMIEKDELNDMTCFIVAKPEEEVSELHLFKDLYQIGSQFIASNSVEEAVLLVASGSGYFILNENTARLINTADLQPLFLLDHGQLIKQKIMAFYKSNSALSSEFIKLLQQEY
>NZ_CP039266.1|WP_005719232.1|1262273_1262822_-|hypothetical-protein
MIFMLKRTLLPLTSMVLVLGLTGLASQVETVDASTYGNGVQVTIPKKMQGTWYSYDRNAHNGTKITFTEHTVNGKPIFTQEASTISDYFNGRIANQKNFDKVTQNWMSGKTTKMKNDTFYEIDPWITFENWSLYRVVPQTINGKKHNVLVYSSRYDGGNYFRSKKLAKKMKDYKFKKVNYTL
>NZ_CP039266.1|WP_065989775.1|1278063_1278591_-|adenine-phosphoribosyltransferase
MAVDFSKYIASVQDFPNKGIVFRDITPILQDGELYRAATHELAEYAKSKKADIIVGPEARGFIVGCPVATELGLGFVPARKPHKLPREVERASYDLEYGSNSLEMHKDAIKPGQRVVLCDDLMATAGTLRASKELIENLGGKLVGAAFYIELPDLHGREKLPDVDIYSLVKYHGA
>NZ_CP039266.1|WP_158181974.1|1278695_1280969_-|single-stranded-DNA-specific-exonuclease-RecJ
MKWQERIADELAPDLIEKYQLGPIAAKLFALRGINTDEKLDFWFNATEENLADPALMHDMDKAINRINQAIDSGEKITIYGDYDADGITATTIMTETLSILGADVHYFIPNRFNDGYGPNMDRYQDIVADGTRLIITVDNGVTGVEEVKYAQEHNVDVIVTDHHTFQEKKPAAYATVHCNYPGQKYPFDDYCGAGVAYTICRGLMQDTMPELLDLAMIGTIGDMVEVTGEGHIIVKRGLEMLNQTDRPGLRALIKNAGLTLGSINETDVGFNIAPRLNAVGRLDNSNLAVELLLSDDDLEAQKIADKIEELNNKRKELTTEVYDKCMTLIHKNSWQKQNTLVLYDPEFHEGVLGLVANKIVEKTHKPTIVLTKNDAGEVKGSGRSFAGFNLFDALNPIKDQYLTKFGGHDFACGLSLEENQIAPLREKFEDDFHIEGGLETKKYDMELPMQGLTPQTLAQINQVGPFGTGDTQPIFSISNPTITHFFKMGKDKNHVKFTVAKKGGNLSVIGFNKGFLNNNLLPFISQIFVQLSLNTYRNQVSLQGIMTGLAFASPKLAVPTPVVDLRQEKYVMGFADRYLLFDQKNIPIVRNRLQIDEDKISLVKDYDQTGETVALLDVPRNQIELNAALEKDYQQIYLRFLLDQLPVEQIPAKNYFGAVLKYIYSHPTLKPADYRTVAPYLGLDYDSVLFILRVFFELGFVKLDEGKLVGEPSPKKQPLTASKYLMGTSSQIKFVNQLRTMPSQRLITYINNLANN
>NZ_CP039266.1|WP_005722136.1|1281092_1281779_-|class-A-sortase
MAKNKKNSVSTILLRVAAIILLLVGIALIFNKQISDQLIHHNQQSTLSGINRKTIEENKKKKGMYDFSKVKSLGIAQAARSQVKKTSGAIGALAIPDVNMYLPIMLGMSDDAMSTGGGTMRADQVMGKGNYPLAGHYMTAKGILFSPLEDVKKGELVYLTNLNKVYVYRIYMKKIVDPTAVWLVDNTKKNIVTLITCADGGKNRWAIRGNLIKTEKANNNNLKVFKLK
>NZ_CP039266.1|WP_158181975.1|1281781_1283620_-|elongation-factor-4
MDLEKLKDYQKHIRNFAIVAHIDHGKSTIADRILELTDTVSQRQLKNQMLDDMPLERQRGITIKMNSVEVKYHAEDGEDYIFHLIDTPGHVDFSYEVSRSLAACEGALMVVDASQGVQAQTLANTYLAIDDDLAILPVINKIDLPSADVPKTKEEIEEMLGLDASEAAEVSGKTGQGIKDMLEKVVKDIPAPAGDIEAPLKALIFDSKYDDYRGVVMSVKIEDGSVKPGDRIQIMNTGKEYEVTEVGVSSPHPIKKDILIAGDVGYITANIKSVRETRVGDTITQADNPTAEPLPGYRQIPPMVYSGMYPVDNRDYEDLKEALQKLQLNDAALEFEPETSTALGFGFRCGFLGLLHMDVVQERLEQEFDLDLIMTAPSVDYHAIMNDGTTKVIDNPSDLPDAGEYKEVQEPYVKAEIMVPNDFVGPVMELCQRKRGEFVTMDYLDKYRVNVIYNMPLAEIIFDFFDDLKSSTKGYASLDYEITGYRATDLVKIDILLNKEPIDALSFIAHRSEAQDRARQMTSMLKKLIPRQNFEVDIQGAIGAKIISRATIKPYRKDVTWKIHTGDPDRRAKLLEKQKRGKKRMKAVGRVEVPQDAFMAVLKMNDDDIKGK
>NZ_CP039266.1|WP_013086487.1|1283727_1284183_+|NUDIX-domain-containing-protein
MITEKSAGAIIWRKQKSQLEYLMIQSQPYKQFPSAWGFTKGHLEGTESNEDAAQREVYEEVGLNPKFDFTFHQVDTYHLTKNRQKEVTFFLAEFIEGQQIKLQESEIRQSAWLSYDEAQKCLAAQNYKEFSYKELQLILKKANSYLLNKTK
>NZ_CP039266.1|WP_005719254.1|1284242_1285394_-|molecular-chaperone-DnaJ
MAQEDYYKVLGVDRDASDQEISRAYRKLAKKYHPDLNHEPGAEEKYKQVNEAYEVLHDKQKRAQYDQFGSAGVNGQGGFGGGAGQGFGGAGFDTSGFGDFGDIFGDIFGQGRQQRVDPTAPQRGQDLDYQLTIDFMDAIKGKKTQVSYTRSETCETCGGNGCEKGTHPITCDKCHGTGYMTITQQSMLGMIRRQTTCDKCHGRGVIIEHPCKTCGGKGTVDRKNTIEVDIPAGIDNGQQLRYQGQGEAGINGGPYGDLYINYRIKPSKDFERRGQTIYTEVPISFAQATLGDEINVKTVHGDVKLTIPAGTQPNKKFTLRGQGVPYLRGNGNGDQITTVNIVIPKHINDKQKKDLTNFVHDGGGNITPQEKGFFERLKDKFNM
>NZ_CP039266.1|WP_013086488.1|1285476_1287330_-|molecular-chaperone-DnaK
MSKVIGIDLGTTNSAVAVLEGKEPKIITNPEGNRTTPSVVAFKDGEIQVGEVAKRQAITNPNTIVSIKRHMGEADYKVKVGDKEYTPQEISAFILQYIKKFSEDYLGEEVKDAVITVPAYFNDAQRQATKDAGKIAGLNVQRIINEPTASALAFGLNKDQDEKVLVYDLGGGTFDVSVLQLGDGVFQVLSTNGDTHLGGDDFDHRIMDWLIKNFKDENGVDLSKDKMAMQRLKDAAEKAKKDLSGVSSTHISLPFISAGEAGPLHLEADLTRAKFDELTADLVEKTKVPFDNALKDAGLTVNDIDKVILNGGSTRIPAVQKAVKEWAGKEPDHSINPDEAVAMGAAIQGGVISGDVKDIVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSKSQIFSTAADNQPAVDVHVLQGERPMAADDKTLGRFELTDIPPAPRGVPQIQVTFDIDKNGIVNVSAKDMGTGKEQKITIKSSSGLSDEEIKRMQKDAEEHADEDKKRKEEADLRNEVDQLIFTTDKTLKDTKDKLSDSDRKPVEDALEALKKAQKDNNLDEMKEKKDALSKAAQDLAVKLYQQNGGAAGQAGPQAGPQGPQGGNSNNGNNGDAQDGEFHKVDPNK
>NZ_CP039266.1|WP_057726509.1|1287346_1287931_-|nucleotide-exchange-factor-GrpE
MSKEEFPSEKNLEQKEKTSEPKAKKEADKGEEKKQEKNKQDQKLAKELADLKDKNKDLEDKYLRSEAEIQNMQNRYTKERAQLIKYESQSLAKDILPAMDNLERALSVEADDDVSKQLKKGVKMTLDALVKAMKDHGVVEIEADGVKFDPTLHQAVQTVAAENDDQKDHVVQVLQKGYQYKDRTLRPAMVVVAQ
>NZ_CP039266.1|WP_100733361.1|1287943_1288993_-|heat-inducible-transcriptional-repressor-HrcA
MLTERQELILKTIITDFTQSHEPVGSKTVMKQLPIKVSSATIRNEMAVLEEQGLIEKTHSSSGRIPSSEGYRYYLDNLVEPLQLPESVYNTIGSQLDRPFHQVNEIVQEAARILSDLTNYTAFAEGPESHDVRVTGFRIVPLSQRQIMAILVTNDGNIQNQVYALPHNIHGEEIEKAVRMINDQLVGKSLNEINVSLLSELAKNELGGEHVTELLSLVEDVVKDAASEQMYVDGQINLLNNTSEHDVNDIRSLYELIDHNNLFTNLMDAKVDPKSGNYPVKVKLGSELPNDLLKNYSLLTAEYSVGSHGKGTIALLGPTNMPYSQMIGLLEYFRNELAKKLLDYYGKFQ
>NZ_CP039266.1|WP_100733360.1|1289130_1290066_-|riboflavin-biosynthesis-protein-RibF
MKIVHLTYPVKENILSTRIVLALGFFDGVHLGHQRLINQAKEIALQKKLSLVVLTFDRHPKEVYESKRDFKYLETLEEKANKMAELGVDYLAVLPFTKNFSQISAQEFVDNVIVRLNADTVVAGFDYTYGSKNIANMANLPQFSKGRFNIVVMPKQTFNGRKIGSTEIRQAIKDGQMELATELMGHHYVMSGIIGHGKRNGHKLGYPTANLIWAEHKVIPKIGVYATKTKVNGKWYNSMTSVGYNVTINQDKKIYIESNIFDFNEDVYGKPMKIKWYKYTRGEKKFAGLPELKEQLERDEQEIRAYFKQKG

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Crispr_ID: NZ_CP039266_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP039266_5

1986751-1986815

Orphan

Consensus_repeat	Method
TTTACTTTATAAAGGAAATAATATG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP039266_5

>merge|NZ_CP039266|5|1986751-1986815|CRISPRCasFinder
TTTACTTTATAAAGGAAATAATATGAAATTTTTGCTATAATTTACTTTATAAAGGAAATAATATG

>NZ_CP039266|5|5|1986751-1986815|CRISPRCasFinder
TTTACTTTATAAAGGAAATAATATG	AAATTTTTGCTATAA
TTTACTTTATAAAGGAAATAATATG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP039266.1\|WP_057726314.1\|1985736_1986342_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378890
NZ_CP039266.1\|WP_158182182.1\|1989030_1990341_+\|NCS2-family-permease	unknown	unknown	gnl\|CDD\|225161
NZ_CP039266.1\|WP_052084611.1\|1994180_1994957_-\|aminoglycoside-nucleotidyltransferase-ANT(9)	unknown	unknown	gnl\|CDD\|184296
NZ_CP039266.1\|WP_005726656.1\|1998173_1998551_+\|cupredoxin-domain-containing-protein	unknown	unknown	gnl\|CDD\|379208
NZ_CP039266.1\|WP_005720719.1\|1984763_1985030_+\|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin	unknown	unknown	gnl\|CDD\|274102
NZ_CP039266.1\|WP_158182179.1\|1982377_1983103_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133381
NZ_CP039266.1\|WP_089703644.1\|1994981_1995752_-\|nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|350158
NZ_CP039266.1\|WP_019543803.1\|1992206_1992701_-\|lincosamide-nucleotidyltransferase-Lnu(C)	unknown	unknown	gnl\|CDD\|371202
NZ_CP039266.1\|WP_158182180.1\|1986345_1986723_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|225117
NZ_CP039266.1\|WP_158182181.1\|1988103_1988877_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|319819
NZ_CP039266.1\|WP_054832713.1\|1997717_1998158_+\|CopY/TcrY-family-copper-transport-repressor	unknown	unknown	gnl\|CDD\|131745
NZ_CP039266.1\|WP_013087079.1\|1983286_1984597_+\|NCS2-family-permease	unknown	unknown	gnl\|CDD\|225161
NZ_CP039266.1\|WP_158182178.1\|1980800_1981103_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039266.1\|WP_058962567.1\|1992724_1993762_-\|IS1595-like-element-ISSag10-family-transposase	unknown	unknown	gnl\|CDD\|226202
NZ_CP039266.1\|WP_131501530.1\|1981105_1982293_+\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NZ_CP039266.1\|WP_005726925.1\|1977984_1978785_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|319818
NZ_CP039266.1\|WP_005719937.1\|1979013_1980321_+\|NCS2-family-permease	unknown	unknown	gnl\|CDD\|225161
NZ_CP039266.1\|WP_150399247.1\|1998563_1998851_+\|cupredoxin-domain-containing-protein	unknown	unknown	gnl\|CDD\|379208
NZ_CP039266.1\|WP_087231438.1\|1991702_1992131_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369603
NZ_CP039266.1\|WP_005720721.1\|1985019_1985352_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP039266.1\|WP_057726314.1\|1985736_1986342_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|378890	pfam12625, Arabinose_bd, Arabinose-binding domain of AraC transcription regulator, N-term. AraC is a bacterial transcriptional regulatory protein with a DNA-binding domain at the C-terminus, HTH_AraC, pfam00165, and this dimerization domain which harbours the arabinose-binding pocket at the N-terminus. AraC positively and negatively regulates expression of the proteins required for the uptake and catabolism of the sugar L-arabinose 1,2,3].	2.35242e-09
NZ_CP039266.1\|WP_158182182.1\|1989030_1990341_+\|NCS2-family-permease	gnl\|CDD\|225161	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism].	9.80338e-150
NZ_CP039266.1\|WP_052084611.1\|1994180_1994957_-\|aminoglycoside-nucleotidyltransferase-ANT(9)	gnl\|CDD\|184296	PRK13746, PRK13746, aminoglycoside resistance protein; Provisional.	8.75234e-71
NZ_CP039266.1\|WP_005726656.1\|1998173_1998551_+\|cupredoxin-domain-containing-protein	gnl\|CDD\|379208	pfam13473, Cupredoxin_1, Cupredoxin-like domain. The cupredoxin-like fold consists of a beta-sandwich with 7 strands in 2 beta-sheets, which is arranged in a Greek-key beta-barrel.	2.43309e-29
NZ_CP039266.1\|WP_158182179.1\|1982377_1983103_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133381	cd01106, HTH_TipAL-Mta, Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA. Helix-turn-helix (HTH) TipAL, Mta, and SkgA transcription regulators, and related proteins, N-terminal domain. TipAL regulates resistance to and activation by numerous cyclic thiopeptide antibiotics, such as thiostrepton. Mta is a global transcriptional regulator; the N-terminal DNA-binding domain of Mta interacts directly with the promoters of mta, bmr, blt, and ydfK, and induces transcription of these multidrug-efflux transport genes. SkgA has been shown to control stationary-phase expression of catalase-peroxidase in Caulobacter crescentus. These proteins are comprised of distinct domains that harbor an N-terminal active (DNA-binding) site and a regulatory (effector-binding) site. The conserved N-terminal domain of these transcription regulators contains winged HTH motifs that mediate DNA binding. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. Unique to this family, is a TipAL-like, lineage specific Bacilli subgroup, which has five conserved cysteines in the C-terminus of the protein.	9.78069e-32
NZ_CP039266.1\|WP_089703644.1\|1994981_1995752_-\|nucleoside-phosphorylase	gnl\|CDD\|350158	cd09007, NP-I_spr0068, uncharacterized subfamily of the nucleoside phosphorylase-I family. This subfamily is composed of uncharacterized members including Streptococcus pneumoniae hypothetical protein spr0068. The nucleoside phosphorylase-I (NP-I) family members accept a range of purine nucleosides as well as the pyrimidine nucleoside uridine. The NP-1 family includes phosphorolytic nucleosidases such as purine nucleoside phosphorylase (PNP, EC. 2.4.2.1), uridine phosphorylase (UP, EC 2.4.2.3), and 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP, EC 2.4.2.28), and hydrolytic nucleosidases such as AMP nucleosidase (AMN, EC 3.2.2.4) and 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase (MTAN, EC 3.2.2.16). Members of the NP-I family display different physiologically relevant quaternary structures: hexameric (trimer-of-dimers arrangement of Shewanella oneidensis MR-1 UP); homotrimeric (human PNP and Escherichia coli PNPII or XapA); hexameric (with some evidence for co-existence of a trimeric form) such as E. coli PNPI (DeoD); or homodimeric such as human and Trypanosoma brucei UP. The NP-I family is distinct from nucleoside phosphorylase-II, which belongs to a different structural family.	7.75141e-101
NZ_CP039266.1\|WP_019543803.1\|1992206_1992701_-\|lincosamide-nucleotidyltransferase-Lnu(C)	gnl\|CDD\|371202	pfam10706, Aminoglyc_resit, Aminoglycoside-2''-adenylyltransferase. This family is conserved in Bacteria. It confers resistance to kanamycin, gentamicin, and tobramycin. The protein is also produced by plasmids in various bacterial species and confers resistance to essentially all clinically available aminoglycosides except streptomycin, and it eliminates the synergism between aminoglycosides and cell-wall active agents.	0.000291574
NZ_CP039266.1\|WP_158182180.1\|1986345_1986723_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	4.1802e-16
NZ_CP039266.1\|WP_158182181.1\|1988103_1988877_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|319819	cd07517, HAD_HPP, phosphatase, similar to Bacteroides thetaiotaomicron VPI-5482 BT4131 hexose phosphate phosphatase; belongs to the haloacid dehalogenase-like superfamily. Bacteroides thetaiotaomicron VPI-5482 BT4131 is a phosphatase with preference for hexose phosphates. In addition this family includes uncharacterized Bacillus subtilis YkrA, a putative phosphatase and uncharacterized Streptococcus pyogenes MGAS10394 a putative bifunctional phosphatase/peptidyl-prolyl cis-trans isomerase. Members of this family belong to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.15923e-56
NZ_CP039266.1\|WP_054832713.1\|1997717_1998158_+\|CopY/TcrY-family-copper-transport-repressor	gnl\|CDD\|131745	TIGR02698, Uncharacterized_16.5_kDa_protein_in_ptsI_3'region, copper transport repressor, CopY/TcrY family. This family includes metal-fist type transcriptional repressors of copper transport systems such as copYZAB of Enterococcus hirae and tcrYAZB (transferble copper resistance) of an Enterocuccus faecium plasmid. High levels of copper can displace zinc and prevent binding by the repressor, activating efflux by copper resistance transporters. The most closely related proteins excluded by this model are antibiotic resistance regulators including the methicillin resistance regulatory protein MecI. [Transport and binding proteins, Cations and iron carrying compounds, Regulatory functions, DNA interactions].	3.71026e-53
NZ_CP039266.1\|WP_005720719.1\|1984763_1985030_+\|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin	gnl\|CDD\|274102	TIGR02384, Putative_antitoxin_RelB, addiction module antitoxin, RelB/DinJ family. Plasmids may be maintained stably in bacterial populations through the action of addiction modules, in which a toxin and antidote are encoded in a cassette on the plasmid. In any daughter cell that lacks the plasmid, the toxin persists and is lethal after the antidote protein is depleted. Toxin/antitoxin pairs are also found on main chromosomes, and likely represent selfish DNA. Sequences in the seed for this alignment all were found adjacent to toxin genes. The resulting model appears to describe a narrower set of proteins than pfam04221, although many in the scope of this model are not obviously paired with toxin proteins. Several toxin/antitoxin pairs may occur in a single species. [Cellular processes, Toxin production and resistance, Mobile and extrachromosomal element functions, Other].	5.57912e-13
NZ_CP039266.1\|WP_058962567.1\|1992724_1993762_-\|IS1595-like-element-ISSag10-family-transposase	gnl\|CDD\|226202	COG3677, COG3677, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.92066e-16
NZ_CP039266.1\|WP_131501530.1\|1981105_1982293_+\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	4.9912e-06
NZ_CP039266.1\|WP_005726925.1\|1977984_1978785_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|319818	cd07516, HAD_Pase, phosphatase, similar to Escherichia coli Cof and Thermotoga maritima TM0651; belongs to the haloacid dehalogenase-like superfamily. Escherichia coli Cof is involved in the hydrolysis of HMP-PP (4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate, an intermediate in thiamin biosynthesis), Cof also has phosphatase activity against the coenzymes pyridoxal phosphate (PLP) and FMN. Thermotoga maritima TM0651 acts as a phosphatase with a phosphorylated carbohydrate molecule as a possible substrate. Escherichia coli YbhA is also a member of this family and catalyzes the dephosphorylation of PLP, YbhA can also hydrolyze erythrose-4-phosphate and fructose-1,6-bis-phosphate. Members of this family belong to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.61499e-73
NZ_CP039266.1\|WP_005719937.1\|1979013_1980321_+\|NCS2-family-permease	gnl\|CDD\|225161	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism].	1.4095e-146
NZ_CP039266.1\|WP_150399247.1\|1998563_1998851_+\|cupredoxin-domain-containing-protein	gnl\|CDD\|379208	pfam13473, Cupredoxin_1, Cupredoxin-like domain. The cupredoxin-like fold consists of a beta-sandwich with 7 strands in 2 beta-sheets, which is arranged in a Greek-key beta-barrel.	7.84028e-20
NZ_CP039266.1\|WP_087231438.1\|1991702_1992131_-\|hypothetical-protein	gnl\|CDD\|369603	pfam07931, CPT, Chloramphenicol phosphotransferase-like protein. The members of this family are all similar to chloramphenicol 3-O phosphotransferase (CPT) expressed by Streptomyces venezuelae. Chloramphenicol (Cm) is a metabolite produced by this bacterium that can inhibit ribosomal peptidyl transferase activity and therefore protein production. By transferring a phosphate group to the C-3 hydroxyl group of Cm, CPT inactivates this potentially lethal metabolite.	0.000790354
NZ_CP039266.1\|WP_013087079.1\|1983286_1984597_+\|NCS2-family-permease	gnl\|CDD\|225161	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism].	3.57369e-147

>NZ_CP039266.1|WP_158182180.1|1986345_1986723_+|helix-turn-helix-domain-containing-protein
MWDYFKPELTKRLSELSVDDSTSARVRSILTELLPNGEFTIDDVAKKLGYSKQTLQRKLSSENTTFQKQLNSTREVLALNYLQNTDMTTSDIAYLLGYQGFNSFLHAFSIWKGMSISEYREKMNK
>NZ_CP039266.1|WP_057726314.1|1985736_1986342_+|AraC-family-transcriptional-regulator
MNHFILDGRYEDLLSHYKFNVEEALKKANIPEDCFKKLHPSMSEQQYYNFMAAIGDQISDPFTPIEIATTNPIESFSPPIFAAYSSRNGDIFIKRLAKYKKLIGPLSFKIDEDSKQLSITLTPSNQQYSLPSFLVLSEFAFLVGLLRKTTKEAISPLKITMTSPVNDEQVINFFGCKIESGKSNTITFAKKDLQVNFISYN
>NZ_CP039266.1|WP_005720721.1|1985019_1985352_+|hypothetical-protein
MRTNDIVDIYVAYIDKPGGKNRPVLIIKLLNSKAWLLKITSKYKEKSENIRKHYFPIFDWKKYNLDKPSYIDTKNYLIVTISDLNIEKYRGHFSIADLRKLKDFIDENSN
>NZ_CP039266.1|WP_005720719.1|1984763_1985030_+|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin
MKSYKKIQANVDSSLALQAEGIFQDIGLNTTTAINVFLKKVVATGGIPFELKETPEQKASRELIQSISKIPHKEAKTKKEIEDWLDED
>NZ_CP039266.1|WP_013087079.1|1983286_1984597_+|NCS2-family-permease
MNSISKFFHLKENNTSFKTELLAGLTTFVSMSYILFVNPNVLGASGMDKGALFTVTALSAAFTCIVMGLIANYPIASAPTLGLNAFFTYTVCLGMKVKWQTALAAVFVASILFILLTVFKVREMIIDAIPADIKYAISAGIGLFIAFIGLQGGKLIQNSDSTLVTIGSLNNPTVWITIFGLIITIFLMIARVPGAIFIGMIAAAVFGIVTGQIPMPKGVISSVPSIAPTFGQAVFHIGDINTVQMWIVVFTFLLVTFFDTTGTLIGLVQQAGLMKDNKMPRAGEALAADSSGMLVGSVLGTSPVGAFVESSSGIAVGGRTGLTAVWVGIFFLISTIFSPILSVFTTQVTAPALIIVGVLMAENLAHVHWTNLEIAIPCFLIALGMPLTYSISDGLGWGLIVYPVSMIAAKRFKEITPMMWILFIVFVIYFVVLNVK
>NZ_CP039266.1|WP_158182179.1|1982377_1983103_-|MerR-family-transcriptional-regulator
MSERHGIGEVAKKLQVSTRTLRFYDQKGLLKPTKAENGYRFYNEDQVQQLQVIIYLKELGFSLAKIKTLLQADHAQESLALLVNAQLQSNNEEIEKFQTQQKQLHDLQKILTKQSNLELTDLTKMMTNETILKKFRRRMLVYGLLLDAIEIIGIILAFYFGKRGNDIGVIASVGIMLLVVVFGAFKLSLSYYKAVAYVCPHCGHTFVPSFRTFMFAAHTPKMRRLRCPNCHEKSYCLEVGR
>NZ_CP039266.1|WP_131501530.1|1981105_1982293_+|CPBP-family-intramembrane-metalloprotease
MLSKAKIIFNLQLILNIIFFIYLVLSKNYIKINYIVFSIALLILIVSLFNPKIKIFKLSSNFLEIATLPFIFRYLAINFIQYLGSLNIISLSLIGCLSCLVSFFINFPLAMLNYKKIDNWFLRLISVQALMISYELLAFPLVGNNIIDALLSYRIVDIISFFILAILILKEWKINFKWNLTIVHMNIAQALLVLLLLIFSIWLIGFNQFGNMGSTLSEAFFNWKDIIQTSLNINTTTVLKAITPSFMEEIERLFNISILLLATYKMKYKRWVATLGSAFIFSIGHWPNLLNHMSLNNLSTQMITTFSMGCLFAVIYLCTGKLWLIIAVHFLNDLIGFSITNTSAYSLRMGILSNYCNGMLTNILIFILPLLAVILVLSFKKTRLLINNNIQKAIN
>NZ_CP039266.1|WP_158182178.1|1980800_1981103_+|hypothetical-protein
MKHKKILGLAFVATLGLELLTTTSETALADNTSTNSHQFSGIQYRVMTAVPSELPTDPIVGAPGSPNQFDHFYSPGYISGGSPSHHSHHSKKKPRKGHKH
>NZ_CP039266.1|WP_005719937.1|1979013_1980321_+|NCS2-family-permease
MNFIKSYFQLDKYKTNIRTEFIAGLTTFISMSYILFVNPSVLGASGMNTGAVFTATALAAALGTAIMGIVANYPIGEAPALGINAFFAYTVCIGMHVSWETALASVFVASIIFILITLFKLREKIIDSIPADLKFAISSGIGLFIAFLGLQNGKLIVANKSTLVGLGSLHDPLVWITIFGLLVTVILMILNVPGAIFIGMVLAAIFGICTGQIALPHKVISTAPSLAPTFGQAIFHVKDINSVQMWVVVLTFLLVTFFDTAGTLIGLAQQAGFMKNNKMPRVGKALAADSSAMAVGSILGTSPVGAFVESSAGIAVGGRTGLTAVFVAIFFLISMIFSPLLGVFTSQVTAPALIIVGVLMAQNTAHIHWNKLEIAVPAFLIILGMPLTYSISDGLSWGMITYPICMLAAKRGKEVTPMMWVLFVVFLIFLWVLNF
>NZ_CP039266.1|WP_005726925.1|1977984_1978785_-|Cof-type-HAD-IIB-family-hydrolase
MSAQLIFSDLDGTLINDDLKVTAATRDAIRRQIINGNIFVPASARLPKGMMTVVNQILKVCPFIAYNGALALDETGKVLISRFFNAKEAAEICRYVDEQDNDAAWNIYSGYVWYCSEEKSPRVKNEERIVDVKATPTTINQLEKLQGVHKGLIMGDSADLDRMQEELTAKYPDLTFVRSAENLLEIVLKGVSKASAVKIVAQEYGVDLQNCIAFGDNYNDEDMLEEVGYPFLMGNAPAELKQKFAPEQITADNNHDGVAKALAKIE
>NZ_CP039266.1|WP_158182181.1|1988103_1988877_-|Cof-type-HAD-IIB-family-hydrolase
MSKPKIIFFDIDGTLIEKKKSITPKMLETLHALQDNGIMICIASGRPPVQLSKLGVDFDAYLTFNGSYCYNDQDIVFDNPLRQGDVLQMIQNAQKINRPLAVATKTRIAANGVDEDLKEYFAIGGTDLKVAPDFDVVVDQDTVYQIMVGCREKDYDRLVANTQNAKVTAWWDRAADIIPATGSKGVAIEKVLDYYQIPVSEAIAFGDGGNDIEMLKTVGHGVAMGNATEDVKEIADDICGSVQDDGIFTYCKKHNLI
>NZ_CP039266.1|WP_158182182.1|1989030_1990341_+|NCS2-family-permease
MQTLEKVFHLQDAHTTVKRELIAALTTFVSLSYILFVNPNILHAAGIPKGAAFTVTALATAVGCFLMGFIANYPIALAPTLGSGAFFAYNVCVGMHISWETALAAVLVASVLFILITVFKLRELVVNAIPQDIKYAISAGIGLFIAFIGLKNGQLIVNSDSTLVTLGKFSTPAVWITLFGLILTVVLMALNVPGSIFIGMIVTAIFGMIIGQIPLPHSIISGAPSIAPTFGQAVFHIKDINTAQLWMVVLTFLLVTFFDTAGTLIGMTEQAGMVDKDGKIPRIGRAFLADSTAMVEGAVFGTAPLGTSVESSAGIAMGGRTGLTAIFVGIFFIISMIFSPLLQVIPTTVTAPALIIVGVLMASNLKKIDWEKFEIAFPAFLTVVGMPLTYSISDGLALGLIAYPITMIASKRYKEVSPMMYILFVIFVIFFLVTNL
>NZ_CP039266.1|WP_087231438.1|1991702_1992131_-|hypothetical-protein
MAFHYLSKGAIPPHLPESNEQNLVVIEAFLEAAKRYARGGYDVIVDGIVGPWFLEPWRALVREDYEVHYIVLRASKEETMKRAVERSKLDRKTNVELVETMWEQFCNLGIYESNVIETTTYSIQEAVFAVKEKISSGAALLS
>NZ_CP039266.1|WP_019543803.1|1992206_1992701_-|lincosamide-nucleotidyltransferase-Lnu(C)
MVNITDVKQILQFAIDAEIKVFLDGGWGVDALLGYQSRAHNDIDIFVEKNDYQNFIEIMKANGFYEIKMEYTTLNHTVWEDLKNRIIDLHCFEYTDEGEILYDGDCFPVETFSGKGRIEEIEVSCIEPYSQVMFHLGYEFDENDAHDVKLLCETLHIEIPNEYR
>NZ_CP039266.1|WP_058962567.1|1992724_1993762_-|IS1595-like-element-ISSag10-family-transposase
MPTIKDALDIIGKLTVAEQESLKTMLLSPAFVKSLNIEDFVAKERFANGRVCPLCGCIHVVRNGHRKDGTQRYVCKDCGKSFVIATNSIVSGTRKDLSVWEQYIDCMMNGLSIRKTAVACGIHRNTAFLWRHKILDALQNMADDVTLDGIIEADETFFAISYKGNHSKSKTFAMPRKAHKRGHSTHIRGLSQEKVCVPCAVNRNGLSISKITNTGRVSTIDLHHIYDGRIKTNSTLVTDKMNSYVRFTNANGIDLVQLKTGKAKKGIYNIQHINSYHSQLKRFMRGFNGVSTKYLNNYLVWNNLVNYAKESDMEKRNIFLTFVLATLKTAKCRDLSNRPAVPLVA
>NZ_CP039266.1|WP_052084611.1|1994180_1994957_-|aminoglycoside-nucleotidyltransferase-ANT(9)
MNINEFPQQVNQVISIAETILQGQILGIYLYGSATMNGLRPDSDIDILIITKQELSNSIRADLTKQLLKISGSVGCIEKRPLEVTIINQSDIVPLQFPPKCQYMYGEWLRGEMEAGEYPQACNDPDIMILLWQARKNSITLKGAESKELIPAIPFHEIKKAIRFSLPGLISSFKGDERNVLLTLSRMWFTLVTEEITTKDVAAKWVILKLPERFSPLLTTAKEAYLGNLSDEWETVEKEAMALVEYMKKQIEELLRTE
>NZ_CP039266.1|WP_089703644.1|1994981_1995752_-|nucleoside-phosphorylase
MPLVKHDYPVLEYDTASKAVFQPGNGKKCFPAKAVFAFLGDEVENYAHTHDGIQIDEFESATRRYPIYECLYNQEKICLCPAPVGSAAAVQVLEYLIAGGVTKIISVGSCGVLEDIPENRFLIPVSALRDEGTSYHYLLPSREVEISKAGINAIESALSQKNIPYWEVKTWTTDGFYRETVEMVQYRKEEGCQVVEMECSALAACAKFRKVTWAMLLFSADTLADPHKYQEREWGKTSISIALELALDAVLSVVEE
>NZ_CP039266.1|WP_054832713.1|1997717_1998158_+|CopY/TcrY-family-copper-transport-repressor
MVKLQEKESTISDSEWEIMRIIWTIEPVSSTKIIQELQAKKDWSESTIKTLLRRLVNKNLLNTTKEGRHFVYSAKVNQAQVMTEAAQELLDRMCNMHKGEVILQLLADSPISKNDLAKMKQIIDQKEKTAPETVPCNCLPGKEHLC
>NZ_CP039266.1|WP_005726656.1|1998173_1998551_+|cupredoxin-domain-containing-protein
MEISQIITLIVAILLIGFILWWFFGKHTETVGTANVGQGSQEADIVVKGGYSPSTIVLKQGVPAKVNFDMQDSTACLSHVVFEQLGVDKDLTKQKVTTVDIPTDKKGTYNFACGMDMFHGKVIVK
>NZ_CP039266.1|WP_150399247.1|1998563_1998851_+|cupredoxin-domain-containing-protein
MSIFSKNQTKKVVVNAENHGYKPNTVTFKQGKPARLKFIPSDNMGCMNEVVSKDLNFDQKLDGKKEVTIDIPTDKPGTYTYACGMDMFRGKVVVK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP039266_4	4.7\|1275717\|33\|NZ_CP039266\|CRISPRCasFinder,CRT	1275717-1275749	33	NC_002102	Lactobacillus helveticus DSM 20075 plasmid pLH1, complete sequence	15163-15195	0	1.0
NZ_CP039266_4	4.30\|1275716\|34\|NZ_CP039266\|PILER-CR	1275716-1275749	34	NC_002102	Lactobacillus helveticus DSM 20075 plasmid pLH1, complete sequence	15163-15196	0	1.0
NZ_CP039266_4	4.5\|1275594\|34\|NZ_CP039266\|CRISPRCasFinder,CRT	1275594-1275627	34	NC_019782	Lactobacillus phage AQ113, complete genome	7465-7498	1	0.971
NZ_CP039266_4	4.17\|1276327\|33\|NZ_CP039266\|CRISPRCasFinder,CRT	1276327-1276359	33	NZ_CP021702	Lactobacillus johnsonii strain UMNLJ21 plasmid pUMNLJ21_2 sequence	558-590	1	0.97
NZ_CP039266_4	4.17\|1276327\|33\|NZ_CP039266\|CRISPRCasFinder,CRT	1276327-1276359	33	NZ_CP021702	Lactobacillus johnsonii strain UMNLJ21 plasmid pUMNLJ21_2 sequence	8513-8545	1	0.97
NZ_CP039266_4	4.17\|1276327\|33\|NZ_CP039266\|CRISPRCasFinder,CRT	1276327-1276359	33	NZ_CP021705	Lactobacillus johnsonii strain UMNLJ22 plasmid pUMNLJ22_1 sequence	6043-6075	1	0.97
NZ_CP039266_4	4.17\|1276327\|33\|NZ_CP039266\|CRISPRCasFinder,CRT	1276327-1276359	33	NZ_CP021705	Lactobacillus johnsonii strain UMNLJ22 plasmid pUMNLJ22_1 sequence	13998-14030	1	0.97
NZ_CP039266_4	4.17\|1276327\|33\|NZ_CP039266\|CRISPRCasFinder,CRT	1276327-1276359	33	NZ_CP021705	Lactobacillus johnsonii strain UMNLJ22 plasmid pUMNLJ22_1 sequence	21945-21977	1	0.97
NZ_CP039266_4	4.21\|1276571\|33\|NZ_CP039266\|CRISPRCasFinder,CRT	1276571-1276603	33	NC_019782	Lactobacillus phage AQ113, complete genome	13764-13796	1	0.97
NZ_CP039266_4	4.28\|1275593\|35\|NZ_CP039266\|PILER-CR	1275593-1275627	35	NC_019782	Lactobacillus phage AQ113, complete genome	7465-7499	1	0.971
NZ_CP039266_4	4.40\|1276326\|34\|NZ_CP039266\|PILER-CR	1276326-1276359	34	NZ_CP021705	Lactobacillus johnsonii strain UMNLJ22 plasmid pUMNLJ22_1 sequence	6042-6075	1	0.971
NZ_CP039266_4	4.40\|1276326\|34\|NZ_CP039266\|PILER-CR	1276326-1276359	34	NZ_CP021705	Lactobacillus johnsonii strain UMNLJ22 plasmid pUMNLJ22_1 sequence	13997-14030	1	0.971
NZ_CP039266_4	4.40\|1276326\|34\|NZ_CP039266\|PILER-CR	1276326-1276359	34	NZ_CP021705	Lactobacillus johnsonii strain UMNLJ22 plasmid pUMNLJ22_1 sequence	21944-21977	1	0.971
NZ_CP039266_4	4.40\|1276326\|34\|NZ_CP039266\|PILER-CR	1276326-1276359	34	NZ_CP021702	Lactobacillus johnsonii strain UMNLJ21 plasmid pUMNLJ21_2 sequence	558-591	1	0.971
NZ_CP039266_4	4.40\|1276326\|34\|NZ_CP039266\|PILER-CR	1276326-1276359	34	NZ_CP021702	Lactobacillus johnsonii strain UMNLJ21 plasmid pUMNLJ21_2 sequence	8513-8546	1	0.971
NZ_CP039266_4	4.7\|1275717\|33\|NZ_CP039266\|CRISPRCasFinder,CRT	1275717-1275749	33	NC_001379	Lactobacillus helveticus subsp. jugurti plasmid pLJ1, complete sequence	204-236	2	0.939
NZ_CP039266_4	4.16\|1276266\|33\|NZ_CP039266\|CRISPRCasFinder,CRT	1276266-1276298	33	NC_015603	Lactobacillus kefiranofaciens ZW3 plasmid pWW2, complete sequence	31450-31482	2	0.939
NZ_CP039266_4	4.30\|1275716\|34\|NZ_CP039266\|PILER-CR	1275716-1275749	34	NC_001379	Lactobacillus helveticus subsp. jugurti plasmid pLJ1, complete sequence	204-237	2	0.941
NZ_CP039266_1	1.13\|1185127\|33\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185127-1185159	33	MN856026	Myoviridae sp. isolate 276, complete genome	8676-8708	3	0.909
NZ_CP039266_3	3.6\|1211229\|33\|NZ_CP039266\|CRISPRCasFinder,PILER-CR	1211229-1211261	33	MN856026	Myoviridae sp. isolate 276, complete genome	8676-8708	3	0.909
NZ_CP039266_4	4.39\|1276265\|34\|NZ_CP039266\|PILER-CR	1276265-1276298	34	NC_015603	Lactobacillus kefiranofaciens ZW3 plasmid pWW2, complete sequence	31449-31482	3	0.912
NZ_CP039266_4	4.16\|1276266\|33\|NZ_CP039266\|CRISPRCasFinder,CRT	1276266-1276298	33	NZ_CP012891	Lactobacillus gallinarum strain HFD4 plasmid pMKG01, complete sequence	17829-17861	5	0.848
NZ_CP039266_4	4.16\|1276266\|33\|NZ_CP039266\|CRISPRCasFinder,CRT	1276266-1276298	33	NZ_CP012891	Lactobacillus gallinarum strain HFD4 plasmid pMKG01, complete sequence	22569-22601	5	0.848
NZ_CP039266_4	4.16\|1276266\|33\|NZ_CP039266\|CRISPRCasFinder,CRT	1276266-1276298	33	NZ_CP012891	Lactobacillus gallinarum strain HFD4 plasmid pMKG01, complete sequence	27285-27317	5	0.848
NZ_CP039266_3	3.15\|1211229\|38\|NZ_CP039266\|CRT	1211229-1211266	38	MN856026	Myoviridae sp. isolate 276, complete genome	8671-8708	6	0.842
NZ_CP039266_4	4.39\|1276265\|34\|NZ_CP039266\|PILER-CR	1276265-1276298	34	NZ_CP012891	Lactobacillus gallinarum strain HFD4 plasmid pMKG01, complete sequence	17829-17862	6	0.824
NZ_CP039266_4	4.39\|1276265\|34\|NZ_CP039266\|PILER-CR	1276265-1276298	34	NZ_CP012891	Lactobacillus gallinarum strain HFD4 plasmid pMKG01, complete sequence	22569-22602	6	0.824
NZ_CP039266_4	4.39\|1276265\|34\|NZ_CP039266\|PILER-CR	1276265-1276298	34	NZ_CP012891	Lactobacillus gallinarum strain HFD4 plasmid pMKG01, complete sequence	27285-27318	6	0.824
NZ_CP039266_2	2.12\|1207995\|33\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1207995-1208027	33	MK080312	Salmonella phage Astrid, complete genome	3540-3572	7	0.788
NZ_CP039266_2	2.12\|1207995\|33\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1207995-1208027	33	MT074440	Salmonella phage assan, complete genome	3474-3506	7	0.788
NZ_CP039266_2	2.12\|1207995\|33\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1207995-1208027	33	NC_048862	Salmonella phage astrithr, complete genome	3474-3506	7	0.788
NZ_CP039266_4	4.5\|1275594\|34\|NZ_CP039266\|CRISPRCasFinder,CRT	1275594-1275627	34	NZ_CP014128	Pantoea vagans strain FDAARGOS_160 plasmid unnamed3, complete sequence	196597-196630	7	0.794
NZ_CP039266_4	4.8\|1275778\|33\|NZ_CP039266\|CRISPRCasFinder,CRT	1275778-1275810	33	NZ_CP030354	Novosphingobium sp. P6W plasmid pP6W1, complete sequence	218968-219000	7	0.788
NZ_CP039266_4	4.9\|1275839\|33\|NZ_CP039266\|CRISPRCasFinder,CRT	1275839-1275871	33	NZ_CP030354	Novosphingobium sp. P6W plasmid pP6W1, complete sequence	218968-219000	7	0.788
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP017997	Lactobacillus crustorum strain MN047 plasmid unnamed1, complete sequence	24270-24303	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP016356	Lactobacillus paracasei subsp. paracasei strain TMW 1.1434 plasmid pL11434-1, complete sequence	34355-34388	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP012296	Pediococcus damnosus strain TMW 2.1536 plasmid pL21536-2, complete sequence	10367-10400	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP031186	Lactobacillus brevis strain SA-C12 plasmid pSAC12_A, complete sequence	23686-23719	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP035572	Lactobacillus plantarum strain SRCM103303 plasmid unnamed1	526-559	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP021459	Lactobacillus brevis strain ZLB004 plasmid p3, complete sequence	29426-29459	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP038154	Lactobacillus paracasei strain TCS plasmid unnamed, complete sequence	31514-31547	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	ARNV02000014	Lactobacillus paracasei strain LcY plasmid pYAK, complete sequence, whole genome shotgun sequence	1070-1103	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP012271	Pediococcus damnosus strain TMW 2.1532 plasmid pL21532-2, complete sequence	8525-8558	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP012282	Pediococcus damnosus strain TMW 2.1533 plasmid pL21533-7, complete sequence	34080-34113	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP028270	Pediococcus pentosaceus strain SRCM102740 plasmid unnamed1, complete sequence	45973-46006	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP028267	Pediococcus pentosaceus strain SRCM102739 plasmid unnamed1, complete sequence	32679-32712	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP031173	Lactobacillus brevis strain UCCLBBS124 plasmid pUCCLBBS124_D, complete sequence	8519-8552	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP021931	Lactobacillus plantarum strain TMW 1.1308 plasmid pL11308-1, complete sequence	22178-22211	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP021931	Lactobacillus plantarum strain TMW 1.1308 plasmid pL11308-1, complete sequence	48417-48450	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP014926	Lactobacillus paracollinoides strain TMW 1.1995 plasmid pL11995-2, complete sequence	16720-16753	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP014927	Lactobacillus paracollinoides strain TMW 1.1995 plasmid pL11995-3, complete sequence	15816-15849	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP014932	Lactobacillus paracollinoides strain TMW 1.1995 plasmid pL11995-8, complete sequence	45361-45394	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP024061	Lactobacillus plantarum strain KACC 92189 plasmid unnamed3	9395-9428	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP014884	Lactobacillus backii strain TMW 1.1991 plasmid pL11991-3, complete sequence	54821-54854	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP028265	Pediococcus pentosaceus strain SRCM102738 plasmid unnamed1, complete sequence	55264-55297	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP029548	Lactobacillus paracasei strain EG9 plasmid pEG9B, complete sequence	34899-34932	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP014918	Lactobacillus paracollinoides strain TMW 1.1994 plasmid pL11994-3, complete sequence	26919-26952	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP014920	Lactobacillus paracollinoides strain TMW 1.1994 plasmid pL11994-5, complete sequence	9324-9357	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP014874	Lactobacillus backii strain TMW 1.1989 plasmid pL11989-1, complete sequence	10481-10514	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP014624	Lactobacillus backii strain TMW 1.1988 plasmid L11988-1, complete sequence	34865-34898	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP019736	Lactobacillus brevis strain TMW 1.2108 plasmid pl12108-2, complete sequence	34078-34111	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP035014	Lactobacillus plantarum strain 12_3 plasmid pldB, complete sequence	35707-35740	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP035116	Lactobacillus plantarum strain SRCM103295 plasmid unnamed3	76976-77009	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP035116	Lactobacillus plantarum strain SRCM103295 plasmid unnamed3	135328-135361	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP017262	Lactobacillus paracasei strain FAM18149 plasmid pFAM18149.21, complete sequence	22468-22501	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP012651	Lactobacillus plantarum strain HFC8 isolate Lactobacillus plantarum plasmid pMK03, complete sequence	29034-29067	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP012652	Lactobacillus plantarum strain HFC8 isolate Lactobacillus plantarum plasmid pMK04, complete sequence	1352-1385	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP012652	Lactobacillus plantarum strain HFC8 isolate Lactobacillus plantarum plasmid pMK04, complete sequence	39021-39054	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP017407	Lactobacillus plantarum strain RI-113 plasmid pRI113_1, complete sequence	29902-29935	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP017408	Lactobacillus plantarum strain RI-113 plasmid pRI113_2, complete sequence	3659-3692	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP019582	Lactobacillus helveticus strain LH5 plasmid pCBTLH5_1, complete sequence	7081-7114	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP027191	Lactobacillus sp. CBA3605 plasmid pCBA3605-1, complete sequence	25727-25760	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP023007	Pediococcus pentosaceus strain SS1-3 plasmid pSS1301, complete sequence	11018-11051	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP044229	Lactobacillus rhamnosus strain hsryfm 1301 plasmid pGu1301, complete sequence	5951-5984	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP027195	Lactobacillus sp. CBA3606 plasmid pCBA3606-1, complete sequence	23899-23932	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NC_021904	Lactobacillus plantarum ZJ316 plasmid pLP-ZJ102, complete sequence	15374-15407	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NC_017475	Lactobacillus paracasei plasmid pLC2W, complete sequence	6848-6881	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP019982	Pediococcus inopinatus strain DSM 20285 plasmid pLDW-12, complete sequence	6774-6807	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP019982	Pediococcus inopinatus strain DSM 20285 plasmid pLDW-12, complete sequence	83293-83326	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP013150	Lactobacillus plantarum strain MF1298 plasmid pMF1298-1, complete sequence	58140-58173	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP016600	Leuconostoc lactis strain WiKim40 plasmid pWK40-2, complete sequence	10021-10054	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP014934	Pediococcus claussenii strain TMW 2.53 plasmid pL253-1, complete sequence	37273-37306	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP041658	Lactobacillus paracasei strain CBA3611 plasmid pLP1, complete sequence	58892-58925	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NC_008502	Lactobacillus paracasei ATCC 334 plasmid 1, complete sequence	5205-5238	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP039709	Lactobacillus paracasei strain Lp02 plasmid pLp02-2, complete sequence	22701-22734	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP031202	Lactobacillus brevis strain UCCLBBS449 plasmid pUCCLBBS449_D, complete sequence	2336-2369	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP022956	Lactobacillus paracasei subsp. paracasei strain IBB3423 plasmid pLCAKO.2, complete sequence	23507-23540	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP014986	Lactobacillus paracasei strain IIA plasmid unnamed1, complete sequence	29211-29244	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP014988	Lactobacillus paracasei strain IIA plasmid unnamed3, complete sequence	16773-16806	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP017699	Lactobacillus coryniformis subsp. torquens DSM 20004 = KCTC 3535 plasmid pLDW-5, complete sequence	22359-22392	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP035308	Lactobacillus helveticus strain IDCC3801 plasmid pHel23910, complete sequence	17429-17462	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP018178	Lactobacillus hordei strain TMW 1.1822 plasmid pL11822-2, complete sequence	4733-4766	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP021926	Pediococcus pentosaceus strain SRCM100194 plasmid pPP194-1, complete sequence	16846-16879	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP050806	Lactobacillus plantarum strain SPC-SNU 72-2 plasmid pLBP752, complete sequence	25113-25146	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP050806	Lactobacillus plantarum strain SPC-SNU 72-2 plasmid pLBP752, complete sequence	73351-73384	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP034948	Enterococcus faecium strain NM213 plasmid unnamed5, complete sequence	101090-101123	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	AQPP01000018	Lactobacillus paracasei strain LcA plasmid pACT, complete sequence, whole genome shotgun sequence	1070-1103	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP019324	Lactobacillus allii strain WiKim39 plasmid pWIKIM01, complete sequence	24283-24316	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP025498	Lactobacillus paracasei subsp. tolerans strain 7112-2 plasmid p7112201, complete sequence	19455-19488	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NC_013200	Lactobacillus rhamnosus Lc 705 plasmid pLC1, complete sequence	55191-55224	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP014937	Pediococcus claussenii strain TMW 2.54 plasmid pL254-1, complete sequence	37274-37307	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP014900	Lactobacillus backii strain TMW 1.2002 plasmid pL12002-1, complete sequence	3465-3498	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP028337	Lactobacillus plantarum strain SRCM101167 plasmid unnamed3, complete sequence	2575-2608	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP012188	Lactobacillus paracasei strain CAUH35 plasmid unnamed1, complete sequence	34709-34742	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP014893	Lactobacillus backii strain TMW 1.1992 plasmid pL11992-3, complete sequence	30292-30325	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP012292	Pediococcus damnosus strain TMW 2.1535 plasmid pL21535-4, complete sequence	34119-34152	8	0.765
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP019745	Lactobacillus brevis strain TMW 1.2111 plasmid pl12111-2, complete sequence	68188-68221	8	0.765
NZ_CP039266_2	2.3\|1207446\|33\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1207446-1207478	33	MN693184	Marine virus AFVG_25M66, complete genome	23349-23381	8	0.758
NZ_CP039266_2	2.12\|1207995\|33\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1207995-1208027	33	NZ_CP014235	Moraxella osloensis strain CCUG 350 plasmid unnamed4, complete sequence	44600-44632	8	0.758
NZ_CP039266_4	4.6\|1275656\|33\|NZ_CP039266\|CRISPRCasFinder,CRT	1275656-1275688	33	NZ_AP014579	Burkholderia sp. RPE67 plasmid p1, complete sequence	1304693-1304725	8	0.758
NZ_CP039266_4	4.6\|1275656\|33\|NZ_CP039266\|CRISPRCasFinder,CRT	1275656-1275688	33	NC_016626	Burkholderia sp. YI23 plasmid byi_1p, complete sequence	1157397-1157429	8	0.758
NZ_CP039266_4	4.11\|1275961\|33\|NZ_CP039266\|CRISPRCasFinder,CRT	1275961-1275993	33	MH791414	UNVERIFIED: Aeromonas phage Aswh_1, complete genome	199347-199379	8	0.758
NZ_CP039266_4	4.31\|1275777\|34\|NZ_CP039266\|PILER-CR	1275777-1275810	34	NZ_CP030354	Novosphingobium sp. P6W plasmid pP6W1, complete sequence	218967-219000	8	0.765
NZ_CP039266_4	4.32\|1275838\|34\|NZ_CP039266\|PILER-CR	1275838-1275871	34	NZ_CP030354	Novosphingobium sp. P6W plasmid pP6W1, complete sequence	218967-219000	8	0.765
NZ_CP039266_1	1.2\|1184454\|33\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1184454-1184486	33	NC_025128	Vibrio vulnificus 48/10 plasmid p48/10 complete sequence	59864-59896	9	0.727
NZ_CP039266_1	1.2\|1184454\|33\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1184454-1184486	33	NZ_CP053824	Vibrio cholerae strain E7G plasmid pE7G, complete sequence	73648-73680	9	0.727
NZ_CP039266_1	1.2\|1184454\|33\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1184454-1184486	33	NZ_CP053819	Vibrio cholerae strain SA7G plasmid pSA7G2, complete sequence	72303-72335	9	0.727
NZ_CP039266_1	1.7\|1184759\|33\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1184759-1184791	33	NZ_CP015231	Epibacterium mobile F1926 plasmid unnamed1, complete sequence	835500-835532	9	0.727
NZ_CP039266_1	1.12\|1185065\|34\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1185065-1185098	34	NZ_CP020732	Leuconostoc mesenteroides subsp. mesenteroides FM06 plasmid pLm1, complete genome	31002-31035	9	0.735
NZ_CP039266_2	2.14\|1208117\|33\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1208117-1208149	33	NZ_CP029455	Bacillus cereus strain FORC087 plasmid pFORC087.1, complete sequence	336060-336092	9	0.727
NZ_CP039266_2	2.14\|1208117\|33\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1208117-1208149	33	CP024685	Bacillus wiedmannii bv. thuringiensis strain FCC41 plasmid pFCC41-1-490K, complete sequence	20724-20756	9	0.727
NZ_CP039266_2	2.14\|1208117\|33\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1208117-1208149	33	NZ_CP022446	Bacillus cereus C1L plasmid pC1L1, complete sequence	112930-112962	9	0.727
NZ_CP039266_4	4.15\|1276205\|33\|NZ_CP039266\|CRISPRCasFinder,CRT	1276205-1276237	33	NC_014304	Erwinia billingiae Eb661 plasmid pEB102, complete sequence	85292-85324	9	0.727
NZ_CP039266_4	4.19\|1276449\|33\|NZ_CP039266\|CRISPRCasFinder,CRT	1276449-1276481	33	KY883642	Vibrio phage JSF15, complete genome	13083-13115	9	0.727
NZ_CP039266_4	4.29\|1275655\|34\|NZ_CP039266\|PILER-CR	1275655-1275688	34	NZ_AP014579	Burkholderia sp. RPE67 plasmid p1, complete sequence	1304692-1304725	9	0.735
NZ_CP039266_4	4.29\|1275655\|34\|NZ_CP039266\|PILER-CR	1275655-1275688	34	NC_016626	Burkholderia sp. YI23 plasmid byi_1p, complete sequence	1157396-1157429	9	0.735
NZ_CP039266_4	4.34\|1275960\|34\|NZ_CP039266\|PILER-CR	1275960-1275993	34	MH791414	UNVERIFIED: Aeromonas phage Aswh_1, complete genome	199346-199379	9	0.735
NZ_CP039266_4	4.46\|1276693\|32\|NZ_CP039266\|PILER-CR	1276693-1276724	32	NZ_CP012711	Psychrobacter urativorans strain R310.10B plasmid 5, complete sequence	12340-12371	9	0.719
NZ_CP039266_2	2.4\|1207507\|33\|NZ_CP039266\|CRISPRCasFinder,CRT,PILER-CR	1207507-1207539	33	MN855777	Bacteriophage sp. isolate 33, complete genome	544-576	10	0.697
NZ_CP039266_4	4.1\|1275349\|34\|NZ_CP039266\|CRISPRCasFinder,CRT	1275349-1275382	34	KY883642	Vibrio phage JSF15, complete genome	13082-13115	10	0.706
NZ_CP039266_4	4.18\|1276388\|33\|NZ_CP039266\|CRISPRCasFinder,CRT	1276388-1276420	33	NZ_CP054613	Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence	162920-162952	10	0.697
NZ_CP039266_4	4.23\|1276693\|33\|NZ_CP039266\|CRISPRCasFinder,CRT	1276693-1276725	33	NZ_CP012711	Psychrobacter urativorans strain R310.10B plasmid 5, complete sequence	12339-12371	10	0.697
NZ_CP039266_4	4.28\|1275593\|35\|NZ_CP039266\|PILER-CR	1275593-1275627	35	NZ_CP014128	Pantoea vagans strain FDAARGOS_160 plasmid unnamed3, complete sequence	196596-196630	10	0.714
NZ_CP039266_4	4.38\|1276204\|34\|NZ_CP039266\|PILER-CR	1276204-1276237	34	NC_014304	Erwinia billingiae Eb661 plasmid pEB102, complete sequence	85292-85325	10	0.706
NZ_CP039266_4	4.42\|1276448\|34\|NZ_CP039266\|PILER-CR	1276448-1276481	34	KY883642	Vibrio phage JSF15, complete genome	13082-13115	10	0.706
NZ_CP039266_4	4.7\|1275717\|33\|NZ_CP039266\|CRISPRCasFinder,CRT	1275717-1275749	33	MK779875	Lactococcus phage CHPC971, complete genome	32352-32384	11	0.667
NZ_CP039266_4	4.41\|1276387\|34\|NZ_CP039266\|PILER-CR	1276387-1276420	34	NZ_CP054613	Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence	162920-162953	11	0.676
NZ_CP039266_4	4.30\|1275716\|34\|NZ_CP039266\|PILER-CR	1275716-1275749	34	MK779875	Lactococcus phage CHPC971, complete genome	32351-32384	12	0.647

1. spacer 4.7|1275717|33|NZ_CP039266|CRISPRCasFinder,CRT matches to NC_002102 (Lactobacillus helveticus DSM 20075 plasmid pLH1, complete sequence) position: , mismatch: 0, identity: 1.0

taaaggttcaatttttgaacgggtaaagggcta	CRISPR spacer
taaaggttcaatttttgaacgggtaaagggcta	Protospacer
*********************************

2. spacer 4.30|1275716|34|NZ_CP039266|PILER-CR matches to NC_002102 (Lactobacillus helveticus DSM 20075 plasmid pLH1, complete sequence) position: , mismatch: 0, identity: 1.0

ctaaaggttcaatttttgaacgggtaaagggcta	CRISPR spacer
ctaaaggttcaatttttgaacgggtaaagggcta	Protospacer
**********************************

3. spacer 4.5|1275594|34|NZ_CP039266|CRISPRCasFinder,CRT matches to NC_019782 (Lactobacillus phage AQ113, complete genome) position: , mismatch: 1, identity: 0.971

tttaacattgatgtagacaccaggtcttacttta	CRISPR spacer
tttaacattgatgtaggcaccaggtcttacttta	Protospacer
****************.*****************

4. spacer 4.17|1276327|33|NZ_CP039266|CRISPRCasFinder,CRT matches to NZ_CP021702 (Lactobacillus johnsonii strain UMNLJ21 plasmid pUMNLJ21_2 sequence) position: , mismatch: 1, identity: 0.97

agaaggcaaaactagcatgatcactgttagata	CRISPR spacer
agaagacaaaactagcatgatcactgttagata	Protospacer
*****.***************************

5. spacer 4.17|1276327|33|NZ_CP039266|CRISPRCasFinder,CRT matches to NZ_CP021702 (Lactobacillus johnsonii strain UMNLJ21 plasmid pUMNLJ21_2 sequence) position: , mismatch: 1, identity: 0.97

agaaggcaaaactagcatgatcactgttagata	CRISPR spacer
agaagacaaaactagcatgatcactgttagata	Protospacer
*****.***************************

6. spacer 4.17|1276327|33|NZ_CP039266|CRISPRCasFinder,CRT matches to NZ_CP021705 (Lactobacillus johnsonii strain UMNLJ22 plasmid pUMNLJ22_1 sequence) position: , mismatch: 1, identity: 0.97

agaaggcaaaactagcatgatcactgttagata	CRISPR spacer
agaagacaaaactagcatgatcactgttagata	Protospacer
*****.***************************

7. spacer 4.17|1276327|33|NZ_CP039266|CRISPRCasFinder,CRT matches to NZ_CP021705 (Lactobacillus johnsonii strain UMNLJ22 plasmid pUMNLJ22_1 sequence) position: , mismatch: 1, identity: 0.97

agaaggcaaaactagcatgatcactgttagata	CRISPR spacer
agaagacaaaactagcatgatcactgttagata	Protospacer
*****.***************************

8. spacer 4.17|1276327|33|NZ_CP039266|CRISPRCasFinder,CRT matches to NZ_CP021705 (Lactobacillus johnsonii strain UMNLJ22 plasmid pUMNLJ22_1 sequence) position: , mismatch: 1, identity: 0.97

agaaggcaaaactagcatgatcactgttagata	CRISPR spacer
agaagacaaaactagcatgatcactgttagata	Protospacer
*****.***************************

9. spacer 4.21|1276571|33|NZ_CP039266|CRISPRCasFinder,CRT matches to NC_019782 (Lactobacillus phage AQ113, complete genome) position: , mismatch: 1, identity: 0.97

agaaaccaattattccatatacaggtgacatca	CRISPR spacer
agaaaccaattattccatacacaggtgacatca	Protospacer
*******************.*************

10. spacer 4.28|1275593|35|NZ_CP039266|PILER-CR matches to NC_019782 (Lactobacillus phage AQ113, complete genome) position: , mismatch: 1, identity: 0.971

ctttaacattgatgtagacaccaggtcttacttta	CRISPR spacer
ctttaacattgatgtaggcaccaggtcttacttta	Protospacer
*****************.*****************

11. spacer 4.40|1276326|34|NZ_CP039266|PILER-CR matches to NZ_CP021705 (Lactobacillus johnsonii strain UMNLJ22 plasmid pUMNLJ22_1 sequence) position: , mismatch: 1, identity: 0.971

cagaaggcaaaactagcatgatcactgttagata	CRISPR spacer
cagaagacaaaactagcatgatcactgttagata	Protospacer
******.***************************

12. spacer 4.40|1276326|34|NZ_CP039266|PILER-CR matches to NZ_CP021705 (Lactobacillus johnsonii strain UMNLJ22 plasmid pUMNLJ22_1 sequence) position: , mismatch: 1, identity: 0.971

cagaaggcaaaactagcatgatcactgttagata	CRISPR spacer
cagaagacaaaactagcatgatcactgttagata	Protospacer
******.***************************

13. spacer 4.40|1276326|34|NZ_CP039266|PILER-CR matches to NZ_CP021705 (Lactobacillus johnsonii strain UMNLJ22 plasmid pUMNLJ22_1 sequence) position: , mismatch: 1, identity: 0.971

cagaaggcaaaactagcatgatcactgttagata	CRISPR spacer
cagaagacaaaactagcatgatcactgttagata	Protospacer
******.***************************

14. spacer 4.40|1276326|34|NZ_CP039266|PILER-CR matches to NZ_CP021702 (Lactobacillus johnsonii strain UMNLJ21 plasmid pUMNLJ21_2 sequence) position: , mismatch: 1, identity: 0.971

cagaaggcaaaactagcatgatcactgttagata	CRISPR spacer
cagaagacaaaactagcatgatcactgttagata	Protospacer
******.***************************

15. spacer 4.40|1276326|34|NZ_CP039266|PILER-CR matches to NZ_CP021702 (Lactobacillus johnsonii strain UMNLJ21 plasmid pUMNLJ21_2 sequence) position: , mismatch: 1, identity: 0.971

cagaaggcaaaactagcatgatcactgttagata	CRISPR spacer
cagaagacaaaactagcatgatcactgttagata	Protospacer
******.***************************

16. spacer 4.7|1275717|33|NZ_CP039266|CRISPRCasFinder,CRT matches to NC_001379 (Lactobacillus helveticus subsp. jugurti plasmid pLJ1, complete sequence) position: , mismatch: 2, identity: 0.939

taaaggttcaatttttgaacgggtaaagggcta	CRISPR spacer
tgaaggttcaatttttgaacgggtaacgggcta	Protospacer
*.************************ ******

17. spacer 4.16|1276266|33|NZ_CP039266|CRISPRCasFinder,CRT matches to NC_015603 (Lactobacillus kefiranofaciens ZW3 plasmid pWW2, complete sequence) position: , mismatch: 2, identity: 0.939

ataagattgagaatgcatcattgtggcagcgta	CRISPR spacer
ataagattaagaatgcatcattgtggcagcgga	Protospacer
********.********************** *

18. spacer 4.30|1275716|34|NZ_CP039266|PILER-CR matches to NC_001379 (Lactobacillus helveticus subsp. jugurti plasmid pLJ1, complete sequence) position: , mismatch: 2, identity: 0.941

ctaaaggttcaatttttgaacgggtaaagggcta	CRISPR spacer
ctgaaggttcaatttttgaacgggtaacgggcta	Protospacer
**.************************ ******

19. spacer 1.13|1185127|33|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to MN856026 (Myoviridae sp. isolate 276, complete genome) position: , mismatch: 3, identity: 0.909

aatagaattcagagatagtttaattttaagtgg	CRISPR spacer
tattgaatttagagatagtttaattttaagtgg	Protospacer
 ** *****.***********************

20. spacer 3.6|1211229|33|NZ_CP039266|CRISPRCasFinder,PILER-CR matches to MN856026 (Myoviridae sp. isolate 276, complete genome) position: , mismatch: 3, identity: 0.909

aatagaattcagagatagtttaattttaagtgg	CRISPR spacer
tattgaatttagagatagtttaattttaagtgg	Protospacer
 ** *****.***********************

21. spacer 4.39|1276265|34|NZ_CP039266|PILER-CR matches to NC_015603 (Lactobacillus kefiranofaciens ZW3 plasmid pWW2, complete sequence) position: , mismatch: 3, identity: 0.912

cataagattgagaatgcatcattgtggcagcgta	CRISPR spacer
gataagattaagaatgcatcattgtggcagcgga	Protospacer
 ********.********************** *

22. spacer 4.16|1276266|33|NZ_CP039266|CRISPRCasFinder,CRT matches to NZ_CP012891 (Lactobacillus gallinarum strain HFD4 plasmid pMKG01, complete sequence) position: , mismatch: 5, identity: 0.848

ataagattgagaatgcatcattgtggcagcgta	CRISPR spacer
ataagattgagaatgcatcactttggcaaagga	Protospacer
********************.* *****. * *

23. spacer 4.16|1276266|33|NZ_CP039266|CRISPRCasFinder,CRT matches to NZ_CP012891 (Lactobacillus gallinarum strain HFD4 plasmid pMKG01, complete sequence) position: , mismatch: 5, identity: 0.848

ataagattgagaatgcatcattgtggcagcgta	CRISPR spacer
ataagattgagaatgcatcactttggcaaagga	Protospacer
********************.* *****. * *

24. spacer 4.16|1276266|33|NZ_CP039266|CRISPRCasFinder,CRT matches to NZ_CP012891 (Lactobacillus gallinarum strain HFD4 plasmid pMKG01, complete sequence) position: , mismatch: 5, identity: 0.848

ataagattgagaatgcatcattgtggcagcgta	CRISPR spacer
ataagattgagaatgcatcactttggcaaagga	Protospacer
********************.* *****. * *

25. spacer 3.15|1211229|38|NZ_CP039266|CRT matches to MN856026 (Myoviridae sp. isolate 276, complete genome) position: , mismatch: 6, identity: 0.842

aatagaattcagagatagtttaattttaagtggggatg	CRISPR spacer
tattgaatttagagatagtttaattttaagtggctata	Protospacer
 ** *****.***********************  **.

26. spacer 4.39|1276265|34|NZ_CP039266|PILER-CR matches to NZ_CP012891 (Lactobacillus gallinarum strain HFD4 plasmid pMKG01, complete sequence) position: , mismatch: 6, identity: 0.824

cataagattgagaatgcatcattgtggcagcgta	CRISPR spacer
gataagattgagaatgcatcactttggcaaagga	Protospacer
 ********************.* *****. * *

27. spacer 4.39|1276265|34|NZ_CP039266|PILER-CR matches to NZ_CP012891 (Lactobacillus gallinarum strain HFD4 plasmid pMKG01, complete sequence) position: , mismatch: 6, identity: 0.824

cataagattgagaatgcatcattgtggcagcgta	CRISPR spacer
gataagattgagaatgcatcactttggcaaagga	Protospacer
 ********************.* *****. * *

28. spacer 4.39|1276265|34|NZ_CP039266|PILER-CR matches to NZ_CP012891 (Lactobacillus gallinarum strain HFD4 plasmid pMKG01, complete sequence) position: , mismatch: 6, identity: 0.824

cataagattgagaatgcatcattgtggcagcgta	CRISPR spacer
gataagattgagaatgcatcactttggcaaagga	Protospacer
 ********************.* *****. * *

29. spacer 2.12|1207995|33|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to MK080312 (Salmonella phage Astrid, complete genome) position: , mismatch: 7, identity: 0.788

tatttttgatgagtttcttaccaataaatatta	CRISPR spacer
tgtatttgatgaatttcttactaataaactgta	Protospacer
*.* ********.********.******.  **

30. spacer 2.12|1207995|33|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to MT074440 (Salmonella phage assan, complete genome) position: , mismatch: 7, identity: 0.788

tatttttgatgagtttcttaccaataaatatta	CRISPR spacer
tgtatttgatgaatttcttactaataaactgta	Protospacer
*.* ********.********.******.  **

31. spacer 2.12|1207995|33|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NC_048862 (Salmonella phage astrithr, complete genome) position: , mismatch: 7, identity: 0.788

tatttttgatgagtttcttaccaataaatatta	CRISPR spacer
tgtatttgatgaatttcttactaataaactgta	Protospacer
*.* ********.********.******.  **

32. spacer 4.5|1275594|34|NZ_CP039266|CRISPRCasFinder,CRT matches to NZ_CP014128 (Pantoea vagans strain FDAARGOS_160 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.794

---tttaacattgatgtagacaccaggtcttacttta	CRISPR spacer
ggatt---catggatatagacaccaggtcttactgtt	Protospacer
   **   *** ***.****************** *

33. spacer 4.8|1275778|33|NZ_CP039266|CRISPRCasFinder,CRT matches to NZ_CP030354 (Novosphingobium sp. P6W plasmid pP6W1, complete sequence) position: , mismatch: 7, identity: 0.788

tcaccgatattgttccaagagccgttcttatta	CRISPR spacer
tcatcgatattgttccaaaagccggtgagattg	Protospacer
***.**************.***** *   ***.

34. spacer 4.9|1275839|33|NZ_CP039266|CRISPRCasFinder,CRT matches to NZ_CP030354 (Novosphingobium sp. P6W plasmid pP6W1, complete sequence) position: , mismatch: 7, identity: 0.788

tcaccgatattgttccaagagccgttcttatta	CRISPR spacer
tcatcgatattgttccaaaagccggtgagattg	Protospacer
***.**************.***** *   ***.

35. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP017997 (Lactobacillus crustorum strain MN047 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

36. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP016356 (Lactobacillus paracasei subsp. paracasei strain TMW 1.1434 plasmid pL11434-1, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

37. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012296 (Pediococcus damnosus strain TMW 2.1536 plasmid pL21536-2, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

38. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP031186 (Lactobacillus brevis strain SA-C12 plasmid pSAC12_A, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

39. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP035572 (Lactobacillus plantarum strain SRCM103303 plasmid unnamed1) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

40. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021459 (Lactobacillus brevis strain ZLB004 plasmid p3, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

41. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP038154 (Lactobacillus paracasei strain TCS plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

42. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to ARNV02000014 (Lactobacillus paracasei strain LcY plasmid pYAK, complete sequence, whole genome shotgun sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

43. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012271 (Pediococcus damnosus strain TMW 2.1532 plasmid pL21532-2, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

44. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012282 (Pediococcus damnosus strain TMW 2.1533 plasmid pL21533-7, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

45. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP028270 (Pediococcus pentosaceus strain SRCM102740 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

46. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP028267 (Pediococcus pentosaceus strain SRCM102739 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

47. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP031173 (Lactobacillus brevis strain UCCLBBS124 plasmid pUCCLBBS124_D, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

48. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021931 (Lactobacillus plantarum strain TMW 1.1308 plasmid pL11308-1, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

49. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021931 (Lactobacillus plantarum strain TMW 1.1308 plasmid pL11308-1, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

50. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014926 (Lactobacillus paracollinoides strain TMW 1.1995 plasmid pL11995-2, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

51. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014927 (Lactobacillus paracollinoides strain TMW 1.1995 plasmid pL11995-3, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

52. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014932 (Lactobacillus paracollinoides strain TMW 1.1995 plasmid pL11995-8, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

53. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024061 (Lactobacillus plantarum strain KACC 92189 plasmid unnamed3) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

54. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014884 (Lactobacillus backii strain TMW 1.1991 plasmid pL11991-3, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

55. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP028265 (Pediococcus pentosaceus strain SRCM102738 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

56. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP029548 (Lactobacillus paracasei strain EG9 plasmid pEG9B, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

57. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014918 (Lactobacillus paracollinoides strain TMW 1.1994 plasmid pL11994-3, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

58. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014920 (Lactobacillus paracollinoides strain TMW 1.1994 plasmid pL11994-5, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

59. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014874 (Lactobacillus backii strain TMW 1.1989 plasmid pL11989-1, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

60. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014624 (Lactobacillus backii strain TMW 1.1988 plasmid L11988-1, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

61. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP019736 (Lactobacillus brevis strain TMW 1.2108 plasmid pl12108-2, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

62. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP035014 (Lactobacillus plantarum strain 12_3 plasmid pldB, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

63. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP035116 (Lactobacillus plantarum strain SRCM103295 plasmid unnamed3) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

64. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP035116 (Lactobacillus plantarum strain SRCM103295 plasmid unnamed3) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

65. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP017262 (Lactobacillus paracasei strain FAM18149 plasmid pFAM18149.21, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

66. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012651 (Lactobacillus plantarum strain HFC8 isolate Lactobacillus plantarum plasmid pMK03, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

67. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012652 (Lactobacillus plantarum strain HFC8 isolate Lactobacillus plantarum plasmid pMK04, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

68. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012652 (Lactobacillus plantarum strain HFC8 isolate Lactobacillus plantarum plasmid pMK04, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

69. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP017407 (Lactobacillus plantarum strain RI-113 plasmid pRI113_1, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

70. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP017408 (Lactobacillus plantarum strain RI-113 plasmid pRI113_2, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

71. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP019582 (Lactobacillus helveticus strain LH5 plasmid pCBTLH5_1, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

72. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP027191 (Lactobacillus sp. CBA3605 plasmid pCBA3605-1, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

73. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023007 (Pediococcus pentosaceus strain SS1-3 plasmid pSS1301, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

74. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP044229 (Lactobacillus rhamnosus strain hsryfm 1301 plasmid pGu1301, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

75. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP027195 (Lactobacillus sp. CBA3606 plasmid pCBA3606-1, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

76. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NC_021904 (Lactobacillus plantarum ZJ316 plasmid pLP-ZJ102, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

77. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NC_017475 (Lactobacillus paracasei plasmid pLC2W, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

78. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP019982 (Pediococcus inopinatus strain DSM 20285 plasmid pLDW-12, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

79. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP019982 (Pediococcus inopinatus strain DSM 20285 plasmid pLDW-12, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

80. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013150 (Lactobacillus plantarum strain MF1298 plasmid pMF1298-1, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

81. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP016600 (Leuconostoc lactis strain WiKim40 plasmid pWK40-2, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

82. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014934 (Pediococcus claussenii strain TMW 2.53 plasmid pL253-1, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

83. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP041658 (Lactobacillus paracasei strain CBA3611 plasmid pLP1, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

84. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NC_008502 (Lactobacillus paracasei ATCC 334 plasmid 1, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

85. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP039709 (Lactobacillus paracasei strain Lp02 plasmid pLp02-2, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

86. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP031202 (Lactobacillus brevis strain UCCLBBS449 plasmid pUCCLBBS449_D, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

87. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022956 (Lactobacillus paracasei subsp. paracasei strain IBB3423 plasmid pLCAKO.2, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

88. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014986 (Lactobacillus paracasei strain IIA plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

89. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014988 (Lactobacillus paracasei strain IIA plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

90. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP017699 (Lactobacillus coryniformis subsp. torquens DSM 20004 = KCTC 3535 plasmid pLDW-5, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

91. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP035308 (Lactobacillus helveticus strain IDCC3801 plasmid pHel23910, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

92. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP018178 (Lactobacillus hordei strain TMW 1.1822 plasmid pL11822-2, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

93. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021926 (Pediococcus pentosaceus strain SRCM100194 plasmid pPP194-1, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

94. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP050806 (Lactobacillus plantarum strain SPC-SNU 72-2 plasmid pLBP752, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

95. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP050806 (Lactobacillus plantarum strain SPC-SNU 72-2 plasmid pLBP752, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

96. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP034948 (Enterococcus faecium strain NM213 plasmid unnamed5, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

97. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to AQPP01000018 (Lactobacillus paracasei strain LcA plasmid pACT, complete sequence, whole genome shotgun sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

98. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP019324 (Lactobacillus allii strain WiKim39 plasmid pWIKIM01, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

99. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP025498 (Lactobacillus paracasei subsp. tolerans strain 7112-2 plasmid p7112201, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

100. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NC_013200 (Lactobacillus rhamnosus Lc 705 plasmid pLC1, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

101. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014937 (Pediococcus claussenii strain TMW 2.54 plasmid pL254-1, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

102. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014900 (Lactobacillus backii strain TMW 1.2002 plasmid pL12002-1, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

103. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP028337 (Lactobacillus plantarum strain SRCM101167 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

104. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012188 (Lactobacillus paracasei strain CAUH35 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

105. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014893 (Lactobacillus backii strain TMW 1.1992 plasmid pL11992-3, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

106. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012292 (Pediococcus damnosus strain TMW 2.1535 plasmid pL21535-4, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

107. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP019745 (Lactobacillus brevis strain TMW 1.2111 plasmid pl12111-2, complete sequence) position: , mismatch: 8, identity: 0.765

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagacgcgtgtg	Protospacer
******.************ ****. **.* .*.

108. spacer 2.3|1207446|33|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to MN693184 (Marine virus AFVG_25M66, complete genome) position: , mismatch: 8, identity: 0.758

acaaaagttaaaagccgttcaagtgttcactta	CRISPR spacer
acaaaagttaaaagcagatcaagtttctataga	Protospacer
*************** * ****** *..*.  *

109. spacer 2.12|1207995|33|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014235 (Moraxella osloensis strain CCUG 350 plasmid unnamed4, complete sequence) position: , mismatch: 8, identity: 0.758

tatttttgatgagtttcttaccaataaatatta	CRISPR spacer
tttttttgatgagttttttaccgatactttgtc	Protospacer
* **************.*****.***  *  *

110. spacer 4.6|1275656|33|NZ_CP039266|CRISPRCasFinder,CRT matches to NZ_AP014579 (Burkholderia sp. RPE67 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.758

cttcagttcttcgtcggtcaaacgtttgattcg	CRISPR spacer
cttcagttcctcgtcggtgaaacggacgatcgc	Protospacer
*********.******** *****  .***.

111. spacer 4.6|1275656|33|NZ_CP039266|CRISPRCasFinder,CRT matches to NC_016626 (Burkholderia sp. YI23 plasmid byi_1p, complete sequence) position: , mismatch: 8, identity: 0.758

cttcagttcttcgtcggtcaaacgtttgattcg	CRISPR spacer
cttcagttcctcgtcggtgaaacggacgatcgc	Protospacer
*********.******** *****  .***.

112. spacer 4.11|1275961|33|NZ_CP039266|CRISPRCasFinder,CRT matches to MH791414 (UNVERIFIED: Aeromonas phage Aswh_1, complete genome) position: , mismatch: 8, identity: 0.758

ccatcttttgataacaaaaacttagcaagtgcg	CRISPR spacer
atgtcttttgataacaaaaacttaacaagaagt	Protospacer
 ..*********************.**** .

113. spacer 4.31|1275777|34|NZ_CP039266|PILER-CR matches to NZ_CP030354 (Novosphingobium sp. P6W plasmid pP6W1, complete sequence) position: , mismatch: 8, identity: 0.765

ctcaccgatattgttccaagagccgttcttatta	CRISPR spacer
gtcatcgatattgttccaaaagccggtgagattg	Protospacer
 ***.**************.***** *   ***.

114. spacer 4.32|1275838|34|NZ_CP039266|PILER-CR matches to NZ_CP030354 (Novosphingobium sp. P6W plasmid pP6W1, complete sequence) position: , mismatch: 8, identity: 0.765

ctcaccgatattgttccaagagccgttcttatta	CRISPR spacer
gtcatcgatattgttccaaaagccggtgagattg	Protospacer
 ***.**************.***** *   ***.

115. spacer 1.2|1184454|33|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NC_025128 (Vibrio vulnificus 48/10 plasmid p48/10 complete sequence) position: , mismatch: 9, identity: 0.727

aacaatcagtaattagccagcttgatgatatta	CRISPR spacer
gcacatcagtaaatagccagtttgatgattgtt	Protospacer
.   ******** *******.********  *

116. spacer 1.2|1184454|33|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP053824 (Vibrio cholerae strain E7G plasmid pE7G, complete sequence) position: , mismatch: 9, identity: 0.727

aacaatcagtaattagccagcttgatgatatta	CRISPR spacer
gcacatcagtaaatagccagtttgatgattgtt	Protospacer
.   ******** *******.********  *

117. spacer 1.2|1184454|33|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP053819 (Vibrio cholerae strain SA7G plasmid pSA7G2, complete sequence) position: , mismatch: 9, identity: 0.727

aacaatcagtaattagccagcttgatgatatta	CRISPR spacer
gcacatcagtaaatagccagtttgatgattgtt	Protospacer
.   ******** *******.********  *

118. spacer 1.7|1184759|33|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP015231 (Epibacterium mobile F1926 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.727

attcagacaataagcgcccggctagatcgtctg	CRISPR spacer
cgtgttgcagtaagcgcccggctagatcatcgg	Protospacer
  *   .**.******************.** *

119. spacer 1.12|1185065|34|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP020732 (Leuconostoc mesenteroides subsp. mesenteroides FM06 plasmid pLm1, complete genome) position: , mismatch: 9, identity: 0.735

gataatttaggcaatcagcaggtaatcgtggata	CRISPR spacer
gataatctaggcaatcagctggtagatgcgtgtg	Protospacer
******.************ ****. .*.* .*.

120. spacer 2.14|1208117|33|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP029455 (Bacillus cereus strain FORC087 plasmid pFORC087.1, complete sequence) position: , mismatch: 9, identity: 0.727

actatgactataacacttcaaaaaatgaaccag	CRISPR spacer
tctatgaccatatcacttcaaaaaaacgcccga	Protospacer
 *******.*** ************  . **..

121. spacer 2.14|1208117|33|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to CP024685 (Bacillus wiedmannii bv. thuringiensis strain FCC41 plasmid pFCC41-1-490K, complete sequence) position: , mismatch: 9, identity: 0.727

actatgactataacacttcaaaaaatgaaccag	CRISPR spacer
tctatgaccatatcacttcaaaaaaacgcccga	Protospacer
 *******.*** ************  . **..

122. spacer 2.14|1208117|33|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022446 (Bacillus cereus C1L plasmid pC1L1, complete sequence) position: , mismatch: 9, identity: 0.727

actatgactataacacttcaaaaaatgaaccag	CRISPR spacer
tctatgaccatatcacttcaaaaaaacgcccga	Protospacer
 *******.*** ************  . **..

123. spacer 4.15|1276205|33|NZ_CP039266|CRISPRCasFinder,CRT matches to NC_014304 (Erwinia billingiae Eb661 plasmid pEB102, complete sequence) position: , mismatch: 9, identity: 0.727

tataaattaagtataattacaaaaatccagtaa	CRISPR spacer
ctaaaattaaatataattacaaaactcagctat	Protospacer
.  *******.************* ** . **

124. spacer 4.19|1276449|33|NZ_CP039266|CRISPRCasFinder,CRT matches to KY883642 (Vibrio phage JSF15, complete genome) position: , mismatch: 9, identity: 0.727

acggtatttcgataccaatatgtcgaagaccgg	CRISPR spacer
ttggtatttcgctaccaatgtgtcgacgtcgac	Protospacer
 .********* *******.****** * * .

125. spacer 4.29|1275655|34|NZ_CP039266|PILER-CR matches to NZ_AP014579 (Burkholderia sp. RPE67 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.735

ccttcagttcttcgtcggtcaaacgtttgattcg	CRISPR spacer
gcttcagttcctcgtcggtgaaacggacgatcgc	Protospacer
 *********.******** *****  .***.

126. spacer 4.29|1275655|34|NZ_CP039266|PILER-CR matches to NC_016626 (Burkholderia sp. YI23 plasmid byi_1p, complete sequence) position: , mismatch: 9, identity: 0.735

ccttcagttcttcgtcggtcaaacgtttgattcg	CRISPR spacer
gcttcagttcctcgtcggtgaaacggacgatcgc	Protospacer
 *********.******** *****  .***.

127. spacer 4.34|1275960|34|NZ_CP039266|PILER-CR matches to MH791414 (UNVERIFIED: Aeromonas phage Aswh_1, complete genome) position: , mismatch: 9, identity: 0.735

gccatcttttgataacaaaaacttagcaagtgcg	CRISPR spacer
catgtcttttgataacaaaaacttaacaagaagt	Protospacer
  ..*********************.**** .

128. spacer 4.46|1276693|32|NZ_CP039266|PILER-CR matches to NZ_CP012711 (Psychrobacter urativorans strain R310.10B plasmid 5, complete sequence) position: , mismatch: 9, identity: 0.719

tagaagctggcagcattgaattcgtagttcag	CRISPR spacer
gctaagctggcagcattgaatgcggagcagaa	Protospacer
   ****************** ** **.  *.

129. spacer 2.4|1207507|33|NZ_CP039266|CRISPRCasFinder,CRT,PILER-CR matches to MN855777 (Bacteriophage sp. isolate 33, complete genome) position: , mismatch: 10, identity: 0.697

acactaagaaagtacctggtaatgtttggaata	CRISPR spacer
tgttttggaaagtaactggtaatttttggaaat	Protospacer
   .* .******* ******** *******

130. spacer 4.1|1275349|34|NZ_CP039266|CRISPRCasFinder,CRT matches to KY883642 (Vibrio phage JSF15, complete genome) position: , mismatch: 10, identity: 0.706

cacggtatttcgataccaatatgtcgaagaccgg	CRISPR spacer
gttggtatttcgctaccaatgtgtcgacgtcgac	Protospacer
  .********* *******.****** * * .

131. spacer 4.18|1276388|33|NZ_CP039266|CRISPRCasFinder,CRT matches to NZ_CP054613 (Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence) position: , mismatch: 10, identity: 0.697

aaactttgttgcaaagctggaagagatggttag	CRISPR spacer
tggtgttgttgcacagctggaagagctggcagg	Protospacer
 ... ******** *********** ***. .*

132. spacer 4.23|1276693|33|NZ_CP039266|CRISPRCasFinder,CRT matches to NZ_CP012711 (Psychrobacter urativorans strain R310.10B plasmid 5, complete sequence) position: , mismatch: 10, identity: 0.697

tagaagctggcagcattgaattcgtagttcaga	CRISPR spacer
gctaagctggcagcattgaatgcggagcagaag	Protospacer
   ****************** ** **.  *..

133. spacer 4.28|1275593|35|NZ_CP039266|PILER-CR matches to NZ_CP014128 (Pantoea vagans strain FDAARGOS_160 plasmid unnamed3, complete sequence) position: , mismatch: 10, identity: 0.714

ctttaacattgatgtagacaccaggtcttacttta	CRISPR spacer
tggattcatggatatagacaccaggtcttactgtt	Protospacer
.     *** ***.****************** *

134. spacer 4.38|1276204|34|NZ_CP039266|PILER-CR matches to NC_014304 (Erwinia billingiae Eb661 plasmid pEB102, complete sequence) position: , mismatch: 10, identity: 0.706

ctataaattaagtataattacaaaaatccagtaa	CRISPR spacer
tctaaaattaaatataattacaaaactcagctat	Protospacer
..  *******.************* ** . **

135. spacer 4.42|1276448|34|NZ_CP039266|PILER-CR matches to KY883642 (Vibrio phage JSF15, complete genome) position: , mismatch: 10, identity: 0.706

cacggtatttcgataccaatatgtcgaagaccgg	CRISPR spacer
gttggtatttcgctaccaatgtgtcgacgtcgac	Protospacer
  .********* *******.****** * * .

136. spacer 4.7|1275717|33|NZ_CP039266|CRISPRCasFinder,CRT matches to MK779875 (Lactococcus phage CHPC971, complete genome) position: , mismatch: 11, identity: 0.667

taaaggttcaatttttgaacgggtaaagggcta	CRISPR spacer
aaaaggttcaatttttaaacgtgtaggaaaagt	Protospacer
 ***************.**** ***.....

137. spacer 4.41|1276387|34|NZ_CP039266|PILER-CR matches to NZ_CP054613 (Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence) position: , mismatch: 11, identity: 0.676

caaactttgttgcaaagctggaagagatggttag	CRISPR spacer
ttggtgttgttgcacagctggaagagctggcagg	Protospacer
. ... ******** *********** ***. .*

138. spacer 4.30|1275716|34|NZ_CP039266|PILER-CR matches to MK779875 (Lactococcus phage CHPC971, complete genome) position: , mismatch: 12, identity: 0.647

ctaaaggttcaatttttgaacgggtaaagggcta	CRISPR spacer
aaaaaggttcaatttttaaacgtgtaggaaaagt	Protospacer
  ***************.**** ***.....

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

195390 : 262943

Phaeocystis_globosa_virus(10.0%)

holin,transposase,protease,tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005724067.1\|195390_196653_+\|tRNA	tyrosine--tRNA ligase	K4F5T3	Cronobacter_phage	1.1e-83	41.5
WP_013085742.1\|197072_197429_+	hypothetical protein	NA	NA	NA	NA
WP_150352189.1\|197653_198967_+	C1 family peptidase	R4TV59	Phaeocystis_globosa_virus	1.4e-60	32.2
WP_023488458.1\|198966_199620_+	HD domain-containing protein	S4W232	Pandoravirus	1.1e-05	26.3
WP_089145708.1\|199788_201408_+	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_158181666.1\|201598_203227_+	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_005725391.1\|203399_204542_+	guanosine monophosphate reductase	A0A1V0SHK8	Klosneuvirus	1.1e-61	33.5
WP_005718454.1\|204709_205639_+	ABC transporter permease	NA	NA	NA	NA
WP_005729325.1\|205647_206679_+	ABC transporter permease	NA	NA	NA	NA
WP_005725387.1\|206694_207753_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.8e-19	32.4
WP_005718459.1\|207773_208718_+	ABC transporter ATP-binding protein	A0A1J0FA64	Only_Syngen_Nebraska_virus	2.2e-07	21.2
WP_158181667.1\|208813_210130_-	aminopeptidase	R4TV59	Phaeocystis_globosa_virus	6.8e-63	35.0
WP_089143458.1\|210272_210698_-	Hsp20/alpha crystallin family protein	NA	NA	NA	NA
WP_005724077.1\|210939_211401_+	transcription elongation factor GreA	NA	NA	NA	NA
WP_158181668.1\|211480_212143_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_158181669.1\|212270_212864_-	SOS response-associated peptidase	NA	NA	NA	NA
WP_005718468.1\|212981_214004_+\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_057726212.1\|214019_214499_+	ComE operon protein 2	A7KUY9	Bacillus_phage	7.9e-38	60.7
WP_089145705.1\|214479_215097_+	TPM domain-containing protein	NA	NA	NA	NA
WP_089145435.1\|215394_218061_+	magnesium-translocating P-type ATPase	A7IUR5	Paramecium_bursaria_Chlorella_virus	9.3e-35	21.9
WP_065989853.1\|218389_219979_+	ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_158181670.1\|219997_222217_+	hypothetical protein	NA	NA	NA	NA
WP_065989846.1\|222204_223794_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	5.7e-08	26.0
WP_158181671.1\|223903_225880_+\|tRNA	methionine--tRNA ligase	A0A1V0SHR2	Klosneuvirus	6.7e-99	39.4
WP_158181672.1\|225879_226647_+	YchF/TatD family DNA exonuclease	NA	NA	NA	NA
WP_005718476.1\|226633_227200_+	ribonuclease M5	NA	NA	NA	NA
WP_158181673.1\|227189_228074_+	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	NA	NA	NA	NA
WP_013085757.1\|228135_228393_+	veg protein	NA	NA	NA	NA
WP_013085758.1\|228501_229332_+	pur operon repressor	NA	NA	NA	NA
WP_013085759.1\|229378_230764_+	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	A0A2K9L277	Tupanvirus	2.2e-27	32.7
WP_005718484.1\|230892_231645_+	hypothetical protein	NA	NA	NA	NA
WP_158181674.1\|231775_233545_+	cell division protein	NA	NA	NA	NA
WP_005724087.1\|233772_234747_+	ribose-phosphate diphosphokinase	A0A2K9L8D8	Tupanvirus	1.2e-45	35.8
WP_158181675.1\|234908_235829_+	ROK family protein	NA	NA	NA	NA
WP_089145427.1\|235897_236170_-	hypothetical protein	NA	NA	NA	NA
WP_158181676.1\|236204_237578_-	HD domain-containing protein	A0A1B1ISR1	uncultured_Mediterranean_phage	8.4e-32	33.5
WP_158181677.1\|237693_238098_+	DUF1934 family protein	NA	NA	NA	NA
WP_060462412.1\|238144_238702_+	DNA-directed RNA polymerase subunit delta	NA	NA	NA	NA
WP_158181678.1\|238818_240438_+	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	5.1e-137	47.7
WP_005725365.1\|240569_241865_+	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_158181679.1\|241933_242458_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_005721654.1\|242512_243937_-	C69 family dipeptidase	NA	NA	NA	NA
WP_158181680.1\|244023_244836_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_158181681.1\|244985_246272_-	purine permease	NA	NA	NA	NA
WP_158181682.1\|246278_246857_-	xanthine phosphoribosyltransferase	NA	NA	NA	NA
WP_158181683.1\|247917_249468_+	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	4.0e-22	33.0
WP_158181684.1\|250881_254661_+	LEA family epithelial adhesin	NA	NA	NA	NA
WP_013085784.1\|255643_256258_+\|transposase	IS607 family transposase	Q331V0	Clostridium_botulinum_C_phage	6.4e-56	53.3
WP_089147366.1\|256288_257581_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	C1KFS0	Lactobacillus_virus	6.6e-71	37.9
WP_080514199.1\|258140_258236_-\|holin	putative holin-like toxin	NA	NA	NA	NA
WP_013085779.1\|258394_258730_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_013085780.1\|258879_259902_+	zinc-binding alcohol dehydrogenase family protein	NA	NA	NA	NA
WP_080514199.1\|260090_260186_-\|holin	putative holin-like toxin	NA	NA	NA	NA
WP_158181685.1\|260348_260858_-	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	6.1e-28	41.6
WP_065990121.1\|260927_261443_-	hypothetical protein	NA	NA	NA	NA
WP_158181686.1\|261650_262943_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	C1KFS0	Lactobacillus_virus	1.1e-70	37.9

DBSCAN-SWA_2

669570 : 679202

Streptococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005722725.1\|669570_672411_+	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	3.1e-307	56.2
WP_005722726.1\|672483_673026_+	membrane protein	NA	NA	NA	NA
WP_005718656.1\|673119_674001_+	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	2.4e-08	30.3
WP_005718658.1\|674011_675055_+	YvcK family protein	A1IMD5	Streptococcus_phage	2.6e-86	49.2
WP_005722729.1\|675047_675983_+	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	1.4e-46	34.9
WP_005718663.1\|676047_676632_-	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	1.1e-52	54.4
WP_005718665.1\|676826_678455_+	hypothetical protein	NA	NA	NA	NA
WP_005718667.1\|678563_679202_+	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	2.5e-18	33.2

DBSCAN-SWA_3

1026290 : 1083075

Staphylococcus_phage(18.18%)

integrase,transposase,protease,tRNA

attL 1027770:1027787|attR 1063311:1063328

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005720213.1\|1026290_1027490_+\|tRNA	CCA tRNA nucleotidyltransferase	G3MAR3	Bacillus_virus	1.8e-38	41.5
WP_005720215.1\|1027526_1028192_-	hemolysin III family protein	NA	NA	NA	NA
1027770:1027787	attL	NA	NA	NA	NA
WP_061204686.1\|1028305_1029157_+	DegV family protein	A0A0N9SI50	Staphylococcus_phage	7.3e-18	40.3
WP_005722332.1\|1029159_1029390_+	YozE family protein	NA	NA	NA	NA
WP_023488720.1\|1030925_1031765_+	ribosome biogenesis GTPase YlqF	NA	NA	NA	NA
WP_005720231.1\|1031761_1032514_+	ribonuclease HII	D2TEQ2	Emiliania_huxleyi_virus	1.3e-23	36.0
WP_089147868.1\|1032575_1033424_+	DNA-protecting protein DprA	NA	NA	NA	NA
WP_158181877.1\|1033493_1035605_+	type I DNA topoisomerase	E3T4K4	Cafeteria_roenbergensis_virus	6.5e-100	37.5
WP_065990811.1\|1035627_1036944_+\|tRNA	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	NA	NA	NA	NA
WP_005726225.1\|1036943_1037852_+	tyrosine recombinase XerC	A0A1B1IQT7	uncultured_Mediterranean_phage	6.4e-20	36.2
WP_005720240.1\|1037860_1038385_+	HslU--HslV peptidase proteolytic subunit	NA	NA	NA	NA
WP_061204691.1\|1038396_1039794_+\|protease	ATP-dependent protease ATPase subunit HslU	A0A1B2IB03	Erwinia_phage	3.0e-29	26.7
WP_060462941.1\|1040006_1040903_+	aldose 1-epimerase family protein	NA	NA	NA	NA
WP_158181878.1\|1041934_1042627_+	hypothetical protein	NA	NA	NA	NA
WP_013086325.1\|1042723_1043539_-\|integrase	integrase	NA	NA	NA	NA
WP_005727168.1\|1043803_1044202_+	CrcB family protein	NA	NA	NA	NA
WP_005723027.1\|1044198_1044576_+	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	2.5e-10	34.1
WP_158181879.1\|1044810_1045587_+	amino acid permease	NA	NA	NA	NA
WP_065990373.1\|1045688_1047095_-	dipeptidase PepV	NA	NA	NA	NA
WP_005720258.1\|1047281_1047788_+	hypothetical protein	NA	NA	NA	NA
WP_005727729.1\|1047835_1049308_-	APC family permease	NA	NA	NA	NA
WP_150399336.1\|1049540_1051628_+	putative ornithine decarboxylase	NA	NA	NA	NA
WP_131501744.1\|1051638_1052898_+	aluminum resistance protein	NA	NA	NA	NA
WP_158181880.1\|1053017_1054787_+	DNA helicase RecQ	A0A1V0SBK0	Catovirus	5.9e-78	38.8
WP_061204698.1\|1054867_1055320_+	transcriptional regulator	NA	NA	NA	NA
WP_158182207.1\|1055628_1056456_-\|transposase	IS982 family transposase	NA	NA	NA	NA
WP_158181881.1\|1056630_1057224_+	hypothetical protein	NA	NA	NA	NA
WP_013641883.1\|1057247_1058102_-	hypothetical protein	NA	NA	NA	NA
WP_154486796.1\|1058288_1059146_-\|transposase	IS982 family transposase	NA	NA	NA	NA
WP_158181882.1\|1060218_1062732_+	AAA family ATPase	A0A1B1IVR3	uncultured_Mediterranean_phage	1.6e-137	31.1
WP_005719570.1\|1062882_1063872_+	homocysteine S-methyltransferase	NA	NA	NA	NA
1063311:1063328	attR	NA	NA	NA	NA
WP_065991187.1\|1063957_1065004_-\|transposase	IS30 family transposase	H7BWC8	unidentified_phage	3.2e-47	34.6
WP_158181883.1\|1065029_1065302_+	hypothetical protein	NA	NA	NA	NA
WP_158181884.1\|1065976_1066426_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_023488828.1\|1066442_1067057_+	sugar O-acetyltransferase	NA	NA	NA	NA
WP_158182208.1\|1067202_1068309_+	serine hydrolase	NA	NA	NA	NA
WP_158182209.1\|1068374_1069205_+	pyridoxamine kinase	NA	NA	NA	NA
WP_005719583.1\|1069207_1069774_+	membrane protein	NA	NA	NA	NA
WP_013086342.1\|1069848_1071054_+	L,D-transpeptidase family protein	NA	NA	NA	NA
WP_013086343.1\|1071500_1071956_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_158181885.1\|1071968_1073252_+	peptidase T	NA	NA	NA	NA
WP_005727739.1\|1073604_1074867_-	replication-associated recombination protein A	A0A127AWE7	Bacillus_phage	7.9e-69	38.4
WP_023488757.1\|1075006_1075408_+	Spx/MgsR family RNA polymerase-binding regulatory protein	NA	NA	NA	NA
WP_150352511.1\|1077156_1077594_+	hypothetical protein	NA	NA	NA	NA
WP_005723055.1\|1077861_1079139_-	extracellular solute-binding protein	NA	NA	NA	NA
WP_005722407.1\|1079500_1079866_+	pyridoxamine 5'-phosphate oxidase family protein	NA	NA	NA	NA
WP_035443748.1\|1079969_1081196_+	serine/threonine protein phosphatase	NA	NA	NA	NA
WP_005719604.1\|1081762_1081921_+	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_155515511.1\|1082066_1082207_+	hypothetical protein	NA	NA	NA	NA
WP_158181886.1\|1082286_1083075_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_4

1178003 : 1245253

Lactobacillus_phage(55.17%)

portal,terminase,tRNA,integrase,transposase,tail

attL 1199077:1199093|attR 1251449:1251465

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_158181918.1\|1178003_1180067_-\|tRNA	glycine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_005719721.1\|1180059_1180977_-\|tRNA	glycine--tRNA ligase subunit alpha	NA	NA	NA	NA
WP_158181919.1\|1181236_1181992_-	DNA repair protein RecO	NA	NA	NA	NA
WP_089143288.1\|1182227_1183529_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A288TXV8	Enterococcus_phage	1.9e-62	38.0
WP_131501341.1\|1183802_1183895_-	hypothetical protein	NA	NA	NA	NA
WP_005719725.1\|1185431_1186334_-	GTPase Era	NA	NA	NA	NA
WP_005719727.1\|1186333_1186858_-	rRNA maturation RNase YbeY	NA	NA	NA	NA
WP_005723097.1\|1186860_1187820_-	PhoH family protein	H6X2N1	Pseudomonas_phage	1.7e-47	46.1
WP_013086431.1\|1187845_1188289_-	GatB/YqeY domain-containing protein	A0A292GL36	Xanthomonas_phage	1.9e-14	32.9
WP_002880182.1\|1188449_1188626_-	30S ribosomal protein S21	NA	NA	NA	NA
WP_158181920.1\|1188853_1189690_+	pyruvate, phosphate dikinase/phosphoenolpyruvate synthase regulator	NA	NA	NA	NA
WP_158181921.1\|1189790_1190603_+	hypothetical protein	A0A1S5SBP9	Streptococcus_phage	1.2e-17	33.1
WP_158181922.1\|1191074_1191821_-	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B)	E4ZFQ0	Streptococcus_phage	2.1e-133	98.8
WP_001814874.1\|1191945_1192029_-	23S rRNA methyltransferase attenuation leader peptide	NA	NA	NA	NA
WP_158181923.1\|1192077_1192317_-	peptide-binding protein	A0A1X9I6D5	Streptococcus_phage	5.2e-22	81.5
WP_158181924.1\|1192565_1193837_+\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	2.7e-48	32.6
WP_158181925.1\|1193907_1201479_-	YSIRK-type signal peptide-containing protein	NA	NA	NA	NA
1199077:1199093	attL	NA	NA	NA	NA
WP_158181926.1\|1202379_1203015_-	cyclic nucleotide-binding domain-containing protein	NA	NA	NA	NA
WP_158181927.1\|1203034_1203580_-	DNA-binding protein	NA	NA	NA	NA
WP_057726630.1\|1203579_1203810_-	heavy-metal-associated domain-containing protein	NA	NA	NA	NA
WP_158181928.1\|1203885_1205739_-	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	7.0e-90	34.1
WP_158181929.1\|1206387_1206945_-	hypothetical protein	NA	NA	NA	NA
WP_005719132.1\|1208609_1209233_+	M23 family metallopeptidase	NA	NA	NA	NA
WP_101887418.1\|1209303_1209870_-	peptide-methionine (S)-S-oxide reductase MsrA	NA	NA	NA	NA
WP_057727000.1\|1211690_1212569_-	YitT family protein	NA	NA	NA	NA
WP_158181930.1\|1213020_1213878_-	SEC10/PgrA surface exclusion domain-containing protein	NA	NA	NA	NA
WP_158181931.1\|1213989_1214877_-	lysin	Q38317	Lactobacillus_phage	1.9e-61	45.0
WP_158181932.1\|1214936_1215269_-	hypothetical protein	NA	NA	NA	NA
WP_158181933.1\|1215271_1215502_-	hypothetical protein	NA	NA	NA	NA
WP_158181934.1\|1216028_1216421_-	hypothetical protein	NA	NA	NA	NA
WP_158181935.1\|1216432_1219270_-	hypothetical protein	NA	NA	NA	NA
WP_158181936.1\|1219270_1219474_-	hypothetical protein	NA	NA	NA	NA
WP_158181937.1\|1219485_1221744_-	hypothetical protein	A0A0A1ELH9	Lactobacillus_phage	9.6e-25	24.7
WP_158181938.1\|1221743_1222562_-	hypothetical protein	A0A0P0IJR2	Lactobacillus_phage	3.1e-18	28.4
WP_158181939.1\|1222565_1225793_-\|tail	phage tail tape measure protein	A0A2P0ZL32	Lactobacillus_phage	1.3e-86	43.7
WP_158181940.1\|1225792_1226098_-	hypothetical protein	NA	NA	NA	NA
WP_158181941.1\|1226241_1226565_-	hypothetical protein	A0A0A1ER95	Lactobacillus_phage	9.2e-22	49.5
WP_158181942.1\|1226646_1227225_-\|tail	phage major tail protein, TP901-1 family	A0A0A1ELH3	Lactobacillus_phage	7.4e-30	42.4
WP_158181943.1\|1227244_1227646_-	DUF3168 domain-containing protein	NA	NA	NA	NA
WP_158181944.1\|1228333_1228729_-	hypothetical protein	A0A0A1ENQ3	Lactobacillus_phage	4.6e-15	47.1
WP_158181945.1\|1228725_1229031_-	hypothetical protein	NA	NA	NA	NA
WP_158181946.1\|1229020_1229383_-	hypothetical protein	Q6SED1	Lactobacillus_prophage	1.7e-29	60.0
WP_158181947.1\|1229415_1230315_-	hypothetical protein	A0A0A1ELG8	Lactobacillus_phage	1.4e-59	47.6
WP_158181948.1\|1230359_1231040_-	hypothetical protein	A0A0A1EN85	Lactobacillus_phage	1.4e-16	34.9
WP_158181949.1\|1231187_1232138_-	hypothetical protein	A0A0A1EKX3	Lactobacillus_phage	2.1e-53	37.5
WP_158181950.1\|1232115_1233504_-\|portal	phage portal protein	Q6SED7	Lactobacillus_prophage	1.0e-122	49.7
WP_158181951.1\|1233750_1234989_-\|terminase	PBSX family phage terminase large subunit	A9D9R9	Lactobacillus_prophage	1.3e-137	59.1
WP_158181952.1\|1235007_1235550_-\|terminase	terminase small subunit	Q20DD9	Lactobacillus_phage	2.3e-17	34.3
WP_158181953.1\|1235635_1235995_+	hypothetical protein	NA	NA	NA	NA
WP_158181954.1\|1236677_1237157_-	hypothetical protein	Q6SEE2	Lactobacillus_prophage	3.0e-37	54.2
WP_158181955.1\|1237158_1237587_-	hypothetical protein	NA	NA	NA	NA
WP_158181956.1\|1237604_1238252_-	hypothetical protein	A0A218KDR1	Bacillus_phage	6.8e-16	37.5
WP_158181957.1\|1238395_1239718_-	hypothetical protein	U3PCP1	Lactobacillus_phage	3.6e-88	44.9
WP_158181958.1\|1239803_1240688_-	hypothetical protein	U3PDN3	Lactobacillus_phage	6.9e-19	39.1
WP_158181959.1\|1240794_1241505_-	AAA family ATPase	U3PIS9	Lactobacillus_phage	5.4e-67	53.3
WP_158181960.1\|1241589_1242279_-	hypothetical protein	NA	NA	NA	NA
WP_158181961.1\|1242373_1242826_-	hypothetical protein	NA	NA	NA	NA
WP_158181962.1\|1242862_1243150_-	hypothetical protein	NA	NA	NA	NA
WP_158181963.1\|1243248_1243476_-	helix-turn-helix domain-containing protein	X2CXM8	Lactobacillus_phage	6.5e-06	49.1
WP_158181964.1\|1243645_1244044_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_158181965.1\|1244104_1245253_+\|integrase	tyrosine-type recombinase/integrase	A0A0M9JJ77	Lactobacillus_phage	2.2e-62	35.4
1251449:1251465	attR	NA	NA	NA	NA

DBSCAN-SWA_5

1472143 : 1530327

Bacillus_phage(20.0%)

transposase,protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_158182024.1\|1472143_1473334_+\|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	2.6e-37	28.8
WP_065991187.1\|1473530_1474577_-\|transposase	IS30 family transposase	H7BWC8	unidentified_phage	3.2e-47	34.6
WP_013085675.1\|1475994_1477173_+\|transposase	IS256 family transposase	NA	NA	NA	NA
WP_158182025.1\|1478952_1479228_-	hypothetical protein	NA	NA	NA	NA
WP_068813168.1\|1479237_1479456_-	hypothetical protein	NA	NA	NA	NA
WP_158182026.1\|1479503_1479839_-	toxin-antitoxin system HicB family antitoxin	R4JJS9	Burkholderia_phage	2.7e-16	36.2
WP_060462780.1\|1479838_1480084_-	type II toxin-antitoxin system HicA family toxin	NA	NA	NA	NA
WP_005722211.1\|1480485_1481475_-	hypothetical protein	NA	NA	NA	NA
WP_005723371.1\|1481619_1482534_-	hypothetical protein	NA	NA	NA	NA
WP_005719812.1\|1482823_1484161_-	type I glutamate--ammonia ligase	NA	NA	NA	NA
WP_060462017.1\|1484296_1485547_-	aminotransferase class V-fold PLP-dependent enzyme	NA	NA	NA	NA
WP_013086631.1\|1485539_1486460_-\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_005719815.1\|1486537_1486939_-	rhodanese-like domain-containing protein	NA	NA	NA	NA
WP_005719816.1\|1486997_1487237_-	YqgQ family protein	NA	NA	NA	NA
WP_150397967.1\|1487236_1487923_-\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
WP_005728452.1\|1487956_1488520_-	5-formyltetrahydrofolate cyclo-ligase	NA	NA	NA	NA
WP_003548272.1\|1488574_1488724_-	50S ribosomal protein L33	NA	NA	NA	NA
WP_158182027.1\|1488799_1490908_-	penicillin-binding protein 2	NA	NA	NA	NA
WP_158182028.1\|1490995_1493635_+	YfhO family protein	NA	NA	NA	NA
WP_005719826.1\|1493697_1494621_+	N-acetylglucosamine kinase	NA	NA	NA	NA
WP_005719828.1\|1494888_1495137_+	type II toxin-antitoxin system RelB/DinJ family antitoxin	NA	NA	NA	NA
WP_013086638.1\|1495139_1495433_+	hypothetical protein	NA	NA	NA	NA
WP_005719832.1\|1496180_1496465_+	HU family DNA-binding protein	A7KV42	Bacillus_phage	8.3e-19	53.9
WP_158182029.1\|1496510_1497284_-	ATP-binding cassette domain-containing protein	A0A1V0SD74	Indivirus	5.4e-12	28.5
WP_158182030.1\|1497440_1498712_-	peptidase dimerisation domain-containing protein	NA	NA	NA	NA
WP_158182031.1\|1498907_1500113_-	amidohydrolase family protein	NA	NA	NA	NA
WP_005729018.1\|1500123_1501755_-	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_089150253.1\|1502154_1502970_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_158182032.1\|1505312_1506164_+	lipoprotein	NA	NA	NA	NA
WP_005727148.1\|1506228_1507140_-	L-lactate dehydrogenase	NA	NA	NA	NA
WP_005719856.1\|1507202_1507679_-	transcription elongation factor GreA	NA	NA	NA	NA
WP_158182033.1\|1507757_1510178_-\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_158182034.1\|1510181_1511231_-\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2K9L3A8	Tupanvirus	6.9e-34	37.5
WP_158182035.1\|1511515_1512382_-	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_005723404.1\|1512391_1513132_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.5e-35	35.7
WP_013086654.1\|1513141_1513813_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_023488242.1\|1513793_1514453_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_013086656.1\|1514753_1515104_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_013086657.1\|1515211_1515979_-	RNA methyltransferase	NA	NA	NA	NA
WP_005723409.1\|1516078_1516351_+	acylphosphatase	NA	NA	NA	NA
WP_057726828.1\|1516394_1517360_+	membrane protein insertase YidC	NA	NA	NA	NA
WP_065989624.1\|1517406_1517895_+\|tRNA	aminoacyl-tRNA deacylase	NA	NA	NA	NA
WP_005729000.1\|1517906_1518779_-	Abi family protein	NA	NA	NA	NA
WP_158182036.1\|1518938_1520120_-	hypothetical protein	NA	NA	NA	NA
WP_158182220.1\|1520188_1521145_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_158182037.1\|1521605_1523177_-	HAMP domain-containing protein	Q8QNA2	Ectocarpus_siliculosus_virus	1.0e-09	29.3
WP_158182038.1\|1523154_1523871_-	response regulator	W8CYM9	Bacillus_phage	2.0e-24	29.6
WP_023488249.1\|1524039_1524603_-	DUF177 domain-containing protein	NA	NA	NA	NA
WP_061204909.1\|1524605_1525757_-	nucleotidyltransferase	NA	NA	NA	NA
WP_005719884.1\|1525760_1526108_-	ribosome silencing factor	NA	NA	NA	NA
WP_005719886.1\|1526125_1526719_-	HD domain-containing protein	NA	NA	NA	NA
WP_061204910.1\|1526699_1527347_-	nicotinate-nucleotide adenylyltransferase	NA	NA	NA	NA
WP_158182039.1\|1527358_1528468_-	ribosome biogenesis GTPase YqeH	NA	NA	NA	NA
WP_005719892.1\|1528460_1528985_-	YqeG family HAD IIIA-type phosphatase	NA	NA	NA	NA
WP_005726544.1\|1529175_1530327_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	C1KFS0	Lactobacillus_virus	1.1e-80	42.5

DBSCAN-SWA_6

1540099 : 1602179

Staphylococcus_phage(18.75%)

bacteriocin,protease,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_158182041.1\|1540099_1542034_-\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	8.1e-97	33.7
WP_150399097.1\|1542320_1543229_-	primosomal protein DnaI	S5MU12	Brevibacillus_phage	4.1e-27	28.8
WP_089150644.1\|1543248_1544583_-	chromosome replication initiation protein	NA	NA	NA	NA
WP_005728264.1\|1544585_1545053_-	transcriptional repressor NrdR	NA	NA	NA	NA
WP_158182042.1\|1545055_1545658_-	dephospho-CoA kinase	NA	NA	NA	NA
WP_158182043.1\|1545654_1546485_-	DNA-formamidopyrimidine glycosylase	G3MA33	Bacillus_virus	3.4e-28	33.1
WP_158182044.1\|1546493_1549157_-	DNA polymerase I	A0A218MKQ4	uncultured_virus	3.9e-57	28.3
WP_052543152.1\|1549576_1549813_-	hypothetical protein	NA	NA	NA	NA
WP_158182045.1\|1550011_1550386_-	DUF2513 domain-containing protein	A0A2H4J4K9	uncultured_Caudovirales_phage	1.2e-09	35.2
WP_158182046.1\|1550636_1552073_-	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	1.2e-17	36.2
WP_158182047.1\|1552072_1553551_-	N-6 DNA methylase	A0A220A2U5	Liberibacter_phage	4.2e-13	25.8
WP_158182048.1\|1553564_1555868_-	DEAD/DEAH box helicase family protein	Q5YA94	Bacillus_phage	2.2e-24	26.8
WP_158182049.1\|1556022_1556778_-	hypothetical protein	NA	NA	NA	NA
WP_158182050.1\|1556810_1557533_-	hypothetical protein	NA	NA	NA	NA
WP_158182051.1\|1557616_1557976_-	hypothetical protein	NA	NA	NA	NA
WP_158182052.1\|1557988_1558798_-	hypothetical protein	NA	NA	NA	NA
WP_158182053.1\|1558877_1559213_-	hypothetical protein	NA	NA	NA	NA
WP_065989665.1\|1561917_1562799_-	hypothetical protein	NA	NA	NA	NA
WP_025005298.1\|1562816_1563131_-	type II toxin-antitoxin system RelB/DinJ family antitoxin	NA	NA	NA	NA
WP_158182054.1\|1563535_1564513_-\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_158182223.1\|1564688_1565522_+	aminopeptidase	NA	NA	NA	NA
WP_158182055.1\|1565620_1566598_+	cell surface protein	NA	NA	NA	NA
WP_158182056.1\|1566705_1568040_+	MATE family efflux transporter	NA	NA	NA	NA
WP_158182057.1\|1568096_1569410_-	UDP-N-acetylmuramate--L-alanine ligase	NA	NA	NA	NA
WP_005723469.1\|1569697_1570345_-\|tRNA	DUF4479 and tRNA-binding domain-containing protein	NA	NA	NA	NA
WP_005718117.1\|1570364_1570685_-	thioredoxin family protein	NA	NA	NA	NA
WP_005718114.1\|1571405_1572062_-\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_041811034.1\|1572071_1573283_-	ABC transporter permease	NA	NA	NA	NA
WP_005723474.1\|1573275_1574019_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.2e-19	27.6
WP_013086704.1\|1574109_1574541_+	HIT family protein	D7NW73	Streptomyces_phage	4.5e-08	33.7
WP_005718108.1\|1574550_1574907_+	hypothetical protein	NA	NA	NA	NA
WP_158182058.1\|1575025_1575922_+	peptidylprolyl isomerase	NA	NA	NA	NA
WP_141685534.1\|1576031_1576505_-	aldolase	NA	NA	NA	NA
WP_158182059.1\|1576822_1578115_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	C1KFS0	Lactobacillus_virus	9.6e-70	37.6
WP_013085784.1\|1578145_1578760_-\|transposase	IS607 family transposase	Q331V0	Clostridium_botulinum_C_phage	6.4e-56	53.3
WP_158182060.1\|1578789_1580280_-\|protease	serine protease	NA	NA	NA	NA
WP_005718104.1\|1580641_1581421_-	DUF1828 domain-containing protein	NA	NA	NA	NA
WP_060462899.1\|1581445_1581931_-	hypothetical protein	NA	NA	NA	NA
WP_065989690.1\|1582047_1583025_-	HD domain-containing protein	NA	NA	NA	NA
WP_158182061.1\|1583017_1585513_-	AAA family ATPase	NA	NA	NA	NA
WP_158182062.1\|1585493_1586711_-	phosphoesterase	NA	NA	NA	NA
WP_023488623.1\|1586719_1587070_-	YlbF family regulator	NA	NA	NA	NA
WP_057726724.1\|1587086_1589144_-	PBP1A family penicillin-binding protein	NA	NA	NA	NA
WP_005718094.1\|1589231_1590089_+	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_158182063.1\|1590143_1592516_-	phosphoenolpyruvate synthase	A0A1V0SGR7	Hokovirus	3.9e-125	31.5
WP_005723483.1\|1592532_1593138_-	histidine phosphatase family protein	A0A1X9IGJ2	Lactococcus_phage	8.5e-21	35.9
WP_054832836.1\|1593569_1594322_+	aquaporin family protein	M1GYI5	Paramecium_bursaria_Chlorella_virus	8.1e-21	31.7
WP_158182064.1\|1594331_1596038_-\|transposase	IS1182 family transposase	A0A146ICT8	Staphylococcus_phage	3.9e-87	38.7
WP_005718089.1\|1596373_1597192_-	triphosphoribosyl-dephospho-CoA synthase	NA	NA	NA	NA
WP_158182065.1\|1597297_1598416_+	acyltransferase family protein	NA	NA	NA	NA
WP_068813803.1\|1598412_1599522_-	ATP-binding protein	NA	NA	NA	NA
WP_049148796.1\|1601000_1602179_-\|transposase	IS256 family transposase	NA	NA	NA	NA

DBSCAN-SWA_7

1781102 : 1815668

Lactobacillus_virus(12.5%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020993065.1\|1781102_1782254_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	C1KFS0	Lactobacillus_virus	1.8e-83	43.7
WP_023488188.1\|1782546_1782993_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	NA	NA	NA	NA
WP_131501498.1\|1782995_1783931_+	ribonucleotide-diphosphate reductase subunit beta	A0A0N7CCA3	Skermania_phage	1.4e-46	33.6
WP_057726354.1\|1783970_1784501_-	hypothetical protein	NA	NA	NA	NA
WP_158181987.1\|1784779_1786186_-\|transposase	ISLre2 family transposase	NA	NA	NA	NA
WP_158182130.1\|1786349_1786937_+	hypothetical protein	NA	NA	NA	NA
WP_061205119.1\|1787133_1787619_-	threonine/serine exporter	NA	NA	NA	NA
WP_158182131.1\|1787621_1788392_-	threonine/serine exporter family protein	NA	NA	NA	NA
WP_068813677.1\|1788402_1789944_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	2.2e-44	27.9
WP_005725472.1\|1789958_1790339_-	hypothetical protein	NA	NA	NA	NA
WP_005718179.1\|1790456_1791035_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_158182226.1\|1791409_1791892_+	hypothetical protein	A0A1B1IMZ4	Lactococcus_phage	2.2e-11	32.7
WP_060463889.1\|1791888_1792578_-	DUF554 domain-containing protein	NA	NA	NA	NA
WP_158182132.1\|1792643_1793876_-	LytR family transcriptional regulator	NA	NA	NA	NA
WP_158182133.1\|1794042_1795839_+	oligoendopeptidase F	NA	NA	NA	NA
WP_158181713.1\|1796784_1798011_+\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	1.3e-97	49.4
WP_158182134.1\|1798508_1799042_-	hypothetical protein	NA	NA	NA	NA
WP_158181987.1\|1799182_1800589_-\|transposase	ISLre2 family transposase	NA	NA	NA	NA
WP_087236529.1\|1800832_1802203_-\|transposase	ISNCY family transposase	NA	NA	NA	NA
WP_061205108.1\|1802490_1803285_-	metal ABC transporter permease	NA	NA	NA	NA
WP_101887568.1\|1803284_1803932_-	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	6.6e-19	29.9
WP_158182135.1\|1803959_1804853_-	zinc ABC transporter solute-binding protein	NA	NA	NA	NA
WP_041811225.1\|1805106_1805385_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_158182136.1\|1805602_1807600_-	PTS transporter subunit EIIA	NA	NA	NA	NA
WP_005721020.1\|1807620_1808535_-	1-phosphofructokinase	NA	NA	NA	NA
WP_005721017.1\|1808536_1809292_-	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
WP_089145321.1\|1809599_1810823_-	ABC transporter permease	NA	NA	NA	NA
WP_023488212.1\|1810806_1811703_-	ABC transporter ATP-binding protein	F2Y1V5	Organic_Lake_phycodnavirus	3.3e-05	30.5
WP_013086931.1\|1812118_1812220_-	hypothetical protein	NA	NA	NA	NA
WP_013086932.1\|1812238_1812661_-	hypothetical protein	NA	NA	NA	NA
WP_013086933.1\|1812694_1812889_-	hypothetical protein	NA	NA	NA	NA
WP_003549779.1\|1813021_1813231_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_158182137.1\|1813245_1813785_-	DUF2975 domain-containing protein	NA	NA	NA	NA
WP_143436812.1\|1813789_1813930_-	hypothetical protein	NA	NA	NA	NA
WP_158182138.1\|1814136_1814352_-	hypothetical protein	NA	NA	NA	NA
WP_144856528.1\|1814633_1815668_-\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	4.8e-40	33.0

DBSCAN-SWA_8

1820323 : 1871309

Bacillus_phage(23.53%)

holin,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_158182141.1\|1820323_1821535_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_013086946.1\|1821994_1823194_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_065990731.1\|1823330_1823549_-	hypothetical protein	NA	NA	NA	NA
WP_013086947.1\|1823564_1823972_-	hypothetical protein	NA	NA	NA	NA
WP_013086948.1\|1824103_1824289_-	hypothetical protein	NA	NA	NA	NA
WP_158182142.1\|1824453_1826760_-	DUF4968 domain-containing protein	NA	NA	NA	NA
WP_144856640.1\|1826906_1828310_-	FAD-binding protein	NA	NA	NA	NA
WP_005720986.1\|1828517_1828703_-	hypothetical protein	NA	NA	NA	NA
WP_005720985.1\|1828717_1828909_-	hypothetical protein	NA	NA	NA	NA
WP_005726533.1\|1828984_1829209_-	hypothetical protein	NA	NA	NA	NA
WP_013086951.1\|1829357_1829681_-	enterocin A immunity protein	NA	NA	NA	NA
WP_005721782.1\|1829822_1830572_-	aspartate/glutamate racemase family protein	NA	NA	NA	NA
WP_005720979.1\|1830581_1832153_-	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase	NA	NA	NA	NA
WP_005723778.1\|1832205_1833360_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	1.6e-31	33.8
WP_005720977.1\|1833361_1834048_-	response regulator transcription factor	W8CYM9	Bacillus_phage	2.5e-37	38.1
WP_131501480.1\|1834235_1834529_+	toxin-antitoxin system HicB family antitoxin	A0A0K2CZV4	Paenibacillus_phage	3.0e-11	37.1
WP_089143634.1\|1834739_1835981_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A0P0IJS6	Lactobacillus_phage	1.9e-120	56.7
WP_005727448.1\|1836234_1838088_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	5.2e-45	25.4
WP_158182143.1\|1838109_1839834_-	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	7.6e-38	27.5
WP_131501700.1\|1839980_1840766_-	DUF1129 domain-containing protein	NA	NA	NA	NA
WP_005720971.1\|1840774_1841875_-	redox-regulated ATPase YchF	NA	NA	NA	NA
WP_005723772.1\|1841928_1842192_-	DUF951 domain-containing protein	NA	NA	NA	NA
WP_089145811.1\|1842184_1843072_-	ParB/RepB/Spo0J family partition protein	I3NLC2	Bifidobacterium_phage	1.9e-16	31.7
WP_005721788.1\|1843049_1843829_-	ParA family protein	Q8JL10	Natrialba_phage	2.5e-25	37.2
WP_065990753.1\|1843847_1844684_-	nucleoid occlusion protein	S5VSZ7	Leptospira_phage	2.3e-16	33.5
WP_005720965.1\|1844701_1845424_-	16S rRNA (guanine(527)-N(7))-methyltransferase RsmG	NA	NA	NA	NA
WP_005720964.1\|1845585_1846122_+	CvpA family protein	NA	NA	NA	NA
WP_158182144.1\|1846278_1846446_+\|holin	putative holin-like toxin	NA	NA	NA	NA
WP_057726587.1\|1846538_1847468_-	FAD:protein FMN transferase	NA	NA	NA	NA
WP_005721790.1\|1847470_1848262_-	tyrosine-protein phosphatase	NA	NA	NA	NA
WP_005720960.1\|1848353_1848902_-	NAD(P)H-dependent oxidoreductase	A0A2P0ZL82	Lactobacillus_phage	3.1e-30	41.0
WP_023488165.1\|1848915_1849455_-	NAD(P)H-dependent oxidoreductase	A0A2P0ZL82	Lactobacillus_phage	2.9e-28	42.0
WP_158182145.1\|1849601_1850225_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_005721791.1\|1850352_1850595_-	hypothetical protein	NA	NA	NA	NA
WP_013086967.1\|1850703_1852116_+	C69 family dipeptidase	NA	NA	NA	NA
WP_005721793.1\|1852148_1852823_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	8.9e-35	39.3
WP_005720107.1\|1852824_1853886_-	ABC transporter permease	NA	NA	NA	NA
WP_005720105.1\|1853888_1854413_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_005720104.1\|1854529_1855129_-	histidine phosphatase family protein	NA	NA	NA	NA
WP_131501703.1\|1855257_1856013_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_013086975.1\|1856009_1856771_-	peroxide stress protein YaaA	NA	NA	NA	NA
WP_005721800.1\|1856829_1857474_+	hypothetical protein	NA	NA	NA	NA
WP_005723748.1\|1857557_1858355_-	DUF4931 domain-containing protein	NA	NA	NA	NA
WP_158182146.1\|1858512_1859715_+	L,D-transpeptidase family protein	NA	NA	NA	NA
WP_013086978.1\|1859806_1859998_+	hypothetical protein	NA	NA	NA	NA
WP_065990769.1\|1860179_1861511_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A288TXV8	Enterococcus_phage	1.4e-60	38.0
WP_013086980.1\|1861674_1862448_-	membrane protein	NA	NA	NA	NA
WP_013086981.1\|1862450_1862900_-	LytTR family transcriptional regulator	NA	NA	NA	NA
WP_158182147.1\|1863040_1863322_-	hypothetical protein	NA	NA	NA	NA
WP_158182148.1\|1863380_1864874_-	MFS transporter	A0A0P0IY73	Acinetobacter_phage	1.6e-76	36.8
WP_158182149.1\|1864988_1867526_-	peptidase	A0A0P0IY26	Acinetobacter_phage	1.0e-67	25.9
WP_005726721.1\|1867739_1868102_+	hypothetical protein	A0A0E3XCL7	Enterococcus_phage	1.5e-20	67.1
WP_158182150.1\|1868173_1869157_-	cytochrome C5	NA	NA	NA	NA
WP_158182151.1\|1869309_1870557_+	MFS transporter	NA	NA	NA	NA
WP_013085784.1\|1870694_1871309_+\|transposase	IS607 family transposase	Q331V0	Clostridium_botulinum_C_phage	6.4e-56	53.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP039266

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection