CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP047147	Streptomyces sp. GF20 chromosome, complete genome	42 crisprs	WYL,cas4,DEDDh,Cas9_archaeal,csa3,Cas14u_CAS-V,cas3,DinG,cas5,cas8c,cas7b	7	46	2	0

1. NZ_CP047147

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP047147_1

• CRISPR_ID: NZ_CP047147_1
• CRISPR_location: 1166220-1166407
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP047147_1

Consensus_repeat	Method
GGAGTAGCCGACCATGTTGTGGTGGATGCGG	PILER-CR

spacers of NZ_CP047147_1

>1.1|1166251|62|NZ_CP047147|PILER-CR
TTGTTCTCGAAGCGGGCGTGGTTCTGCGGGAGGCCGGGGTGGCCGGGGAAGGCGCTGTCCAT
>1.2|1166344|43|NZ_CP047147|PILER-CR
CGAACTCGTTGCCGTGGACGTACACGGAGTCCCCGGCGGTGCC

CRISPR arrays and Neighbor proteins around NZ_CP047147_1

CRISPR arrays

The CRISPR arrays of NZ_CP047147_1

>merge|NZ_CP047147|1|1166220-1166407|PILER-CR
AGTAGTCGGCGTTGTTGTGGTGGATGCGGTTGTTCTCGAAGCGGGCGTGGTTCTGCGGGAGGCCGGGGTGGCCGGGGAAGGCGCTGTCCATGGAGGCGCCGCCCATGTTGTGGTCGAACTCGTTGCCGTGGACGTACACGGAGTCCCCGGCGGTGCCGGAGTAGCCGACCATGTTGTGGTGGCTGCGG

>NZ_CP047147|1|1|1166220-1166407|PILER-CR
AGTAGTCGGCGTTGTTGTGGTGGATGCGGTT	GTTCTCGAAGCGGGCGTGGTTCTGCGGGAGGCCGGGGTGGCCGGGGAAGGCGCTGTCCATGG
AGGCGCCGCCCATGTTGTGGTCGAACTCGTT	GCCGTGGACGTACACGGAGTCCCCGGCGGTGCCGGAGTAGCCG
ACCATGTTGTGGTGGCTGCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_008411936.1|1159308_1159773_-|redox-sensitive-transcriptional-activator-SoxR	unknown	unknown	gnl|CDD|133385
NZ_CP047147.1|WP_159311980.1|1177725_1177938_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_129846273.1|1169699_1171877_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|226482
NZ_CP047147.1|WP_129818507.1|1173860_1174973_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NZ_CP047147.1|WP_010636735.1|1159933_1160395_+|MaoC-family-dehydratase	unknown	unknown	gnl|CDD|239534
NZ_CP047147.1|WP_159311979.1|1176625_1177720_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379214
NZ_CP047147.1|WP_003947274.1|1168792_1169539_+|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225099
NZ_CP047147.1|WP_159313851.1|1171983_1173135_+|DNA-methyltransferase	unknown	unknown	gnl|CDD|380119
NZ_CP047147.1|WP_003947261.1|1157298_1157877_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_008414260.1|1175072_1175882_-|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl|CDD|238861
NZ_CP047147.1|WP_159311977.1|1167394_1168717_+|homogentisate-1,2-dioxygenase	unknown	unknown	gnl|CDD|235421
NZ_CP047147.1|WP_159311975.1|1164406_1165207_-|hypothetical-protein	unknown	unknown	gnl|CDD|259885
NZ_CP047147.1|WP_003947262.1|1157937_1158441_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159311974.1|1163117_1164410_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159313850.1|1161240_1162335_-|zinc-binding-dehydrogenase	unknown	unknown	gnl|CDD|176240
NZ_CP047147.1|WP_008411928.1|1162416_1163058_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|380058
NZ_CP047147.1|WP_003947277.1|1173279_1173549_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_015508117.1|1160447_1161125_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|380061
NZ_CP047147.1|WP_159311973.1|1159054_1159279_-|hypothetical-protein	unknown	unknown	gnl|CDD|237030
NZ_CP047147.1|WP_159311978.1|1176192_1176624_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_008411936.1|1159308_1159773_-|redox-sensitive-transcriptional-activator-SoxR	gnl|CDD|133385	cd01110, HTH_SoxR, Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator. Helix-turn-helix (HTH) transcriptional regulator SoxR. The global regulator, SoxR, up-regulates gene expression of another transcription activator, SoxS, which directly stimulates the oxidative stress regulon genes in E. coli. The soxRS response renders the bacterial cell resistant to superoxide-generating agents, macrophage-generated nitric oxide, organic solvents, and antibiotics. The SoxR proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the unusually long spacer between the -35 and -10 promoter elements. They also harbor a regulatory C-terminal domain containing an iron-sulfur center.	7.4476e-78
NZ_CP047147.1|WP_008414260.1|1175072_1175882_-|SGNH/GDSL-hydrolase-family-protein	gnl|CDD|238861	cd01823, SEST_like, SEST_like. A family of secreted SGNH-hydrolases similar to Streptomyces scabies esterase (SEST), a causal agent of the potato scab disease, which hydrolyzes a specific ester bond in suberin, a plant lipid. The tertiary fold of this enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles two of the three components of typical Ser-His-Asp(Glu) triad from other serine hydrolases, but may lack the carboxylic acid.	1.0491e-58
NZ_CP047147.1|WP_159313851.1|1171983_1173135_+|DNA-methyltransferase	gnl|CDD|380119	pfam18135, Type_ISP_C, Type ISP C-terminal specificity domain. This is the C-terminal domain of Type ISP restriction-modification enzyme LLaBIII present in Lactococcus lactis subsp. cremoris. Type ISP restriction-modification (RM) enzymes provide a potent defence against infection by foreign and bacteriophage DNA. This domain interacts extensively with DNA and is known as the target recognition domain (TRD). TRD works by recognising 6/7 base pairs of asymmetric sequence.	9.02776e-40
NZ_CP047147.1|WP_015508117.1|1160447_1161125_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|380061	pfam17932, TetR_C_24, Tetracyclin repressor-like, C-terminal domain. TetR family regulators are involved in the transcriptional control of multidrug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. The TetR proteins identified in overm ultiple genera of bacteria and archaea share a common helix-turn-helix (HTH) structure in their DNA-binding domain. However, TetR proteins can work in different ways: they can bind a target operator directly to exert their effect (e.g. TetR binds Tet(A) gene to repress it in the absence of tetracycline), or they can be involved in complex regulatory cascades in which the TetR protein can either be modulated by another regulator or TetR can trigger the cellular response. TetR regulates the expression of the membrane-associated tetracycline resistance protein, TetA, which exports the tetracycline antibiotic out of the cell before it can attach to the ribosomes and inhibit protein synthesis. TetR blocks transcription from the genes encoding both TetA and TetR in the absence of antibiotic. The C-terminal domain is multi-helical and is interlocked in the homodimer with the helix-turn-helix (HTH) DNA-binding domain. This entry represents the C-terminal domain present in family members such as HTH-type transcriptional repressor KstR2 as well as fatty acid metabolism regulator proteins. In Mycobacterium smegmatis, KstR2 is involved in involved in cholesterol catabolism, while YsiA in Bacillus subtilis is involved in fatty acid degradation.	4.36143e-33
NZ_CP047147.1|WP_003947274.1|1168792_1169539_+|GntR-family-transcriptional-regulator	gnl|CDD|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.72795e-42
NZ_CP047147.1|WP_010636735.1|1159933_1160395_+|MaoC-family-dehydratase	gnl|CDD|239534	cd03450, NodN, NodN (nodulation factor N) contains a single hot dog fold similar to those of the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit. Rhizobium and related species form nodules on the roots of their legume hosts, a symbiotic process that requires production of Nod factors, which are signal molecules involved in root hair deformation and meristematic cell division. The nodulation gene products, including NodN, are involved in producing the Nod factors, however the role played by NodN is unclear.	3.63246e-88
NZ_CP047147.1|WP_159311979.1|1176625_1177720_+|GNAT-family-N-acetyltransferase	gnl|CDD|379214	pfam13480, Acetyltransf_6, Acetyltransferase (GNAT) domain. This family contains proteins with N-acetyltransferase functions.	2.31534e-31
NZ_CP047147.1|WP_159311977.1|1167394_1168717_+|homogentisate-1,2-dioxygenase	gnl|CDD|235421	PRK05341, PRK05341, homogentisate 1,2-dioxygenase; Provisional.	0
NZ_CP047147.1|WP_159311975.1|1164406_1165207_-|hypothetical-protein	gnl|CDD|259885	cd04223, N2OR_C, The C-terminal cupredoxin domain of Nitrous-oxide reductase. Nitrous-oxide reductase participates in nitrogen metabolism and catalyzes the last step in dissimilatory nitrate reduction, the two-electron reduction of N2O to N2. It contains copper ions as cofactors in the form of a binuclear CuA center at the site of electron entry and a tetranuclear CuZ centre at the active site. The C-terminus of Nitrous-oxide reductase is a cupredoxin domain.	0.000236033
NZ_CP047147.1|WP_129818507.1|1173860_1174973_+|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.25914e-96
NZ_CP047147.1|WP_159313850.1|1161240_1162335_-|zinc-binding-dehydrogenase	gnl|CDD|176240	cd08279, Zn_ADH_class_III, Class III alcohol dehydrogenase. Glutathione-dependent formaldehyde dehydrogenases (FDHs, Class III ADH) are members of the zinc-dependent/medium chain alcohol dehydrogenase family. FDH converts formaldehyde and NAD(P) to formate and NAD(P)H. The initial step in this process the spontaneous formation of a S-(hydroxymethyl)glutathione adduct from formaldehyde and glutathione, followed by FDH-mediated oxidation (and detoxification) of the adduct to S-formylglutathione. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. Class III ADH are also known as glutathione-dependent formaldehyde dehydrogenase (FDH), which convert aldehydes to corresponding carboxylic acid and alcohol. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of an beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding.	5.95659e-150
NZ_CP047147.1|WP_008411928.1|1162416_1163058_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|380058	pfam17928, TetR_C_22, Tetracyclin repressor-like, C-terminal domain. TetR family regulators are involved in the transcriptional control of multidrug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. The TetR proteins identified in overm ultiple genera of bacteria and archaea share a common helix-turn-helix (HTH) structure in their DNA-binding domain. However, TetR proteins can work in different ways: they can bind a target operator directly to exert their effect (e.g. TetR binds Tet(A) gene to repress it in the absence of tetracycline), or they can be involved in complex regulatory cascades in which the TetR protein can either be modulated by another regulator or TetR can trigger the cellular response. TetR regulates the expression of the membrane-associated tetracycline resistance protein, TetA, which exports the tetracycline antibiotic out of the cell before it can attach to the ribosomes and inhibit protein synthesis. TetR blocks transcription from the genes encoding both TetA and TetR in the absence of antibiotic. The C-terminal domain is multi-helical and is interlocked in the homodimer with the helix-turn-helix (HTH) DNA-binding domain. This entry represents the C-terminal domain present the TetR Transcriptional Repressor present in sco1712 proteins from Streptomyces coelicolo which act as a regulator of antibiotic production.	9.8451e-17
NZ_CP047147.1|WP_129846273.1|1169699_1171877_+|AAA-family-ATPase	gnl|CDD|226482	COG3973, COG3973, Superfamily I DNA and RNA helicases [General function prediction only].	5.62399e-51
NZ_CP047147.1|WP_159311973.1|1159054_1159279_-|hypothetical-protein	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	0.00242639

Protein sequences

>NZ_CP047147.1|WP_159311975.1|1164406_1165207_-|hypothetical-protein
MNRARAARRTAALAAVLLLAAGCGGRPTTHHRPGTSHEEATAGAGRLLAEKDAAGHRYRELPPGQDPSVRLAARPDSEDGWNLHLTLGRFRLTPDSTGSGAVPGRGHARLLVDGKETARLYGTWHHLPAAGLPGPGPHRLTVRLHADDHTVWVRDGRPVQATHTLGEETGEKSGERTAPPARTVELTVAGGRVTPPVGRTEVNRGDRVTLKVRSDRDDTLHVHGYDKAKKLTAGRTATLTFTADRTGLFEVETHGAHLVLTQLLVR
>NZ_CP047147.1|WP_159311974.1|1163117_1164410_-|hypothetical-protein
MTPLPPAGELATLLAHGVGSRHDLPVSPFYAFAGAFAALLVSFLGLGLLWSRSRLTGEAAGRPLPAAVQRCADARATTLALRALGLAAYLTLLAHLLLGPDDPVRNPAPAAVYALFWAGLVPLSLLCGPLWRRLNPLRTLHLLGRALLRRPEPDRVPPAPLGLWPAALGLAAFTWLELASPAPASRAALLTFLGAYTVLQLAAAARWGEAWFARGDAFEAYAGLLARLSPFGRRADGRLVVRNPLDGLDATERVPGLAATLCVLLGSTAYDGLSGTAGWTGTLQTSPLGRTPTATLGLLAVIGVTGAVYALCTAATRVRDAGAAFAHSLVPVALGYLVAHYFTLFTTEAPHAVALAVGAGPGPVPEPPLEPGALAALQVCAVVTGHVLGVVAAHDRAVRLQPPERAVSGQIPLLVLMITYTLGGLGLLVA
>NZ_CP047147.1|WP_008411928.1|1162416_1163058_-|TetR/AcrR-family-transcriptional-regulator
MDPVQHLTSLRRAPVQQRSAERLVRILDACADLLDEVGYEQLTTRAVADRAQVPIGSVYRFFDNKRALADALAHRNLDRYADRIARRVGEVDGSDWRGAVDACLDEYLTMKRTVPGFTLIDFGVPAPPTDGEPHANHQVADRVAALLAAHLGRPLDDALRRAVLVGVEATDSLLHLAFRTDPAGDEALVGETRTLLHAYFAHTFDRPPGGPGG
>NZ_CP047147.1|WP_159313850.1|1161240_1162335_-|zinc-binding-dehydrogenase
MVRAAFLPATGSALTVGEIDLPDPGPGQVRIRLAAAGVCHSDLSLTNGTMAVPVPAVLGHEGAGTVVAVGEGVASVAPGDGVVLNWAPSCGDCGACGRGEVWLCRNALAGAARVHAHRPDGTVLHPGLNVAAFAEETVVEENCVLPVPDGVPLTDAALLGCAVLTGYGAVHHNARVREGESVVVFGVGGVGLAVLQSARIAGAGAVIAVDVSEAKRDLAHQAGATEFVLASDTTAKEIRALTGGEGADVAIECVGRAATIRTAWESTRRGGRTTVVGIGGTDQQVTFNALELFHWGRTLSGCVYGNSDPVRDLPVLAEHIRAGRLDLASMVTDRIGLEDIPGAFERMTAGKGGRALVEFGQAGR
>NZ_CP047147.1|WP_015508117.1|1160447_1161125_-|TetR/AcrR-family-transcriptional-regulator
MSAVERDPEGSDEVVDESAGEAAGEPDDAAWAEVTPDAARRLLVAAVDAFAERGYHATTTRDIAGRAGMSPAALYIHYKTKEELLHRISRIGHDRALKIMRDAADSGGTAAERLDRAVRSFVGWHALRHTTARVVQYELDALGPEHRAEIIELRRGTDAAVREMISDGVRDGEFEVPDIPGTTLAVISLCIDVARWFKVGGTRTPEEIGALYAGLVLRMVGAGEK
>NZ_CP047147.1|WP_010636735.1|1159933_1160395_+|MaoC-family-dehydratase
MAEPRIFASVDELRAAVGEQLGHTDWLEIEQQRIDQFAEATGDHQWIHVDPEQAKEGPFGTTIAHGYLTLSLLPVFGPQLISVEGVRMGVNYGVNKVRFPAPVPVGSRLRATAQVTEVGEVTGGIQVTTVFTVEREGGDKPVCVAEAVVRYYL
>NZ_CP047147.1|WP_008411936.1|1159308_1159773_-|redox-sensitive-transcriptional-activator-SoxR
MPQIPQKIHELTVGQLSARSGAAVSALHFYEAKGLISSRRTSGNQRRYHRDTLRRVAFVRAAQRVGIPLATIRDALAELPEERTPTHEDWARLSHVWRAELDERINQLHRLRDHLTDCIGCGCLSLETCVLSNPDDTVGASLTGSRLMGARRKA
>NZ_CP047147.1|WP_159311973.1|1159054_1159279_-|hypothetical-protein
MEDDGHTAVTAVVPLTATATAGSPHSRAEKVRTRCGGKRPASRAAQAAPAVPPTAPAASSSPKPASGSPSTLPL
>NZ_CP047147.1|WP_003947262.1|1157937_1158441_-|hypothetical-protein
MGVAVCSLKWEAARTGSQRIVYDSDGYHLVRFPYEESEESYDPWGMHDPGKAYPDPESGLIVPSHDGWGTVSALVFWAPDSRPVEYRARFVRDPLGSSTGYDSTATTDSAPTGGNQFRTYMWQMFVRKDTPLGLKVTARASGDVPVPAALTLAEFKLAVQTDVHVPE
>NZ_CP047147.1|WP_003947261.1|1157298_1157877_+|hypothetical-protein
MAGFRSLARQVRDPRCDLALRRYSLRKCLERFAPYGHRATWDHLCSRHGFGPEDRSPDPARLEAALTEVEEARDLWLAHEARFAARRRREKHDGLRRPAGVDTWQRRTGSGYALAWCDNPRLHPSLPLAEVLRRLLDALDREPGTDCPVCATPHLAWGEGPEPHCVHCGISVPRELLTPRALTQVATPLLAA
>NZ_CP047147.1|WP_159311977.1|1167394_1168717_+|homogentisate-1,2-dioxygenase
MSADGHAPATPAYLTGFGNEHSSEAVPGALPEGRNSPQRAPLGLYAEQLSGTAFTEPRAHNRRSWLYRIRPSAAHPAFVRTGNGTLHGGPFTDAVPDPNRMRWDPLPDPAPGTDFLAGLWTLGGNGDPARREGMAVHLYAAATSMERVFSDADGELLIVPQEGTLRLRTEFGLLVAGPGEIALIPRGVRFRAELSGAPARGYVCENFGRPFQLPDLGPIGANGLANPRDFRAPVAAYEEAEEPVEVVTKYCGNLWRATYGHSPLDVVAWHGNHVPYVYDLRRFNVIGSISYDHPDPSIFTVLTSPSDTPGLAGVDFVAFAPRWLVGEDTFRPPYFHRNVMSEYMGLIDGAYDAKRGGAGGFVPGGGSLHPMMSAHGPDRDTFEKASAAELRPQKIDDGLAFMFETRWPILPTAQAAGAAHRQQGYDGVWQGLERHWGTAG
>NZ_CP047147.1|WP_003947274.1|1168792_1169539_+|GntR-family-transcriptional-regulator
MTAFAPDSIVLNRKLPLWYQVSQSLRASVLGRSPGDPLRLPTEEQLAAHYGVSVLTMRQALKELEDEGLITRHRRRGTFIEPSARQGAPVRLLGSVDAIVAQQSGMRARLLDHGPAPVPAGLAEYFPGRTEVTAYHRLRHDEETGEPTNHARNYLPPEIAARVDPAELEIRPMTKVLRDTVGLSIARITDTVEARLADPETARLLDVPLLSPILHYTGVTVDEEGRTLDVTRIHYRGDRFSFTVTLDA
>NZ_CP047147.1|WP_129846273.1|1169699_1171877_+|AAA-family-ATPase
MRTPSPVPGAESPAAFTAFALPGRLAAKADPALTGGDDRHFAAVTAALEQSVAELTASLDAALRSPGGAGRAAMDRDTEVHRLGARLRTLRRFGLDLCLGHFVREDDPEPVYIGRLGLTDGDGRRLLTDWRSPAAEPFFAATHARPMGLASRRRYRWSGGRISDYWDEVFTADGLEGHAALDDQSAFLASLGGHRSDRMRDVLATIQADQDAIIRAGSRGTLVVDGGPGTGKTVVALHRAAHLLYADPRLGHRRGGVLVVGPHQPYLNYVDDVLPSLGEEGVRTCTLRDLVPEGAAARPEADPEVARLKSSAAMVRAVEPAVALYEEPPTEGMEVVTHWSTLWLSAADWAAAFDAVEPGTPHNEARGQIRDELLTLLMDQDESDAPPALLRRSLLGNRKLIGALNRAWPVIEATDLVGDLWTVPAYLRRCAPHLTVEEVRALQRPVPDAWTLADLPLLDAARQRLGDPRSSVRKLRQDAAVAAERERRAAVVDTLVRADDDGEGAVTMLLHDDLQSTLIDEGALPGAEREPLQGPFAHIVVDEAQELTDAEWQMLRSRCPSRSFTVVGDRAQARHGFAATWPERLERAGLDRITVASLGVNYRTPSEVMTEAEQVIRAALPDANVPSSVRSTGVPVHHGPAADRDALLDAWLAEHAEGVACVIGDPTFTATSRVRSLTPELAKGLEFDLVVLVGPERFGEGVEGAVDRYVAMTRATQRLAVLTGP
>NZ_CP047147.1|WP_159313851.1|1171983_1173135_+|DNA-methyltransferase
MPWSVAPWRPGRDWPLAAEPETLRRRWRALAEAEGERREELFGPTRARTTRSSVAPLPGRTTATGRLARDPGPCPEPVRVLDGPFDARWLLPDHRLLDTARPELWRAHGPHSRYLLETGPGGPPLLATALLPTGRNPYGRARPVRPLHRGPDPADPNLAPGLLPYLAKELGLPVSAGDVFAWIVCAAVPGAGGCEVPLPRQARAWEAGVAWGAAALALLAPLDGDRPRLPGGRRPYVRAPLVPVAAGEEGPYPVAYDAESESLMVGGGRIAPVPPGAWEFICGGVRVLAEWVARRTAVGAPGTLEGLAPGEWPQERTRELLELITVLALLAEAEASRPEVAGPVVGEAELRAAGVLPVPAAARRPGPALAVREEGPEGQSALW
>NZ_CP047147.1|WP_003947277.1|1173279_1173549_-|hypothetical-protein
MEQITVRSRPRVPAITCGSSATSSRLDRHLSVLGGPAVPQRETAEATTLMRELTSRKAAHDRTGRGARVSRVSLFAPLRRLRRSLFGGH
>NZ_CP047147.1|WP_129818507.1|1173860_1174973_+|serine/threonine-protein-kinase
MNTSGTSGRQGRAGGEGHGAPPAARGRLLAGRYRLVGELGRGGMGTVWRARDETLRREVAVKEVSVPFGLPEEDVARLHARLEREARAAGRIEHPGVAEVFDVVRQDGRPWIVMELVRGITLQDVLEADGPLEPERAASVGAEVLSALRAAHGAGVLHRDVKPANVLLALDGRVVLTDFGSSLVEGGEELTDAGEVVGSPEYLAPERALEAEPGPASDLWALGVLLFASVEGRTPFRRETALATLGAAVDDALPAPGRAGPLRPVIEGLLRKHPDDRLCAAEAERLLHRVAGGSRSRGGAMAVVPGARGARRGGGRAEDGGPAGRRSGRGREASGAQRGLRGAGRKAPVLVALAALVVLLAAAAGWLLGW
>NZ_CP047147.1|WP_008414260.1|1175072_1175882_-|SGNH/GDSL-hydrolase-family-protein
MKLRRTATYVTSLLAAVTLALTGASAAAAADAQAAGGYVALGDSYSSGVGAGSYDSGSGDCRRTPKAYPALWAAANSPASFDFVACSGAVTSDVLNKQMGPLNSSTSLVSLTIGGNDAGFADVMTTCVLQSEANCIARVNTAKAFVESTLPGRLDSVYSQVRAKAPSANVVVLGYPRFYKLNGTCVAGLTEGERTAINGAADLLNSVISKRAADHGYAYGDIAAAFTGHEICSGDSWLHSVKWTGINDSYHPTAAGQSGGYLPVLNSKA
>NZ_CP047147.1|WP_159311978.1|1176192_1176624_+|hypothetical-protein
MQTIGMKPSSSLTERHRGSPGGEAPTPVLAAAWCAAVAAGALLALTGPGAPWHSALTSVFLASAPGGAVALALSGLDPWSRAVAALGATLAVNTLVAQALLMLGTWSARTGVVAVGAVGWLVLTGALAGRLVRRRRTARERVG
>NZ_CP047147.1|WP_159311979.1|1176625_1177720_+|GNAT-family-N-acetyltransferase
MDITVHRPGELTAADRAAWSALQRARPPTEAPQLHNPFLAPEFTLAMGACRRDVRIAAVREDGVPTAFFPHQRTPAGVGRAVGLGVSDCQGLVHGPGFTGEAGELLRGAGLALWEFDHLAADQPVFADGAGARFGSPVMDVADGWESYLAGLRERSPKFTRTTLAKERRLDRALGPLRYVHDERDPELLRVLMAWKSAQYRRTGRGDRFAKPWITRLVEHLFHTGPGEVRGLLSVLYAGERPVAAHFGLRSAAVLACWFPAYDPAYAKYSPGLVLHLAMARGAAEDGMTLLDLGRGRKEYKDSLKTRELTVAEGWVTRRHPVAFGHRMRRAPVRALRNTVQGRPELFRPADALLKRMGQFRTGG
>NZ_CP047147.1|WP_159311980.1|1177725_1177938_-|hypothetical-protein
MVLFIGIDLRADLRADLCRDLCSGECADVCVLALLYGRNQDQILLSGIQPDEFRRMTHSLRERPPGAAER

Crispr_ID: NZ_CP047147_2

• CRISPR_ID: NZ_CP047147_2
• CRISPR_location: 1553673-1553777
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP047147_2

Consensus_repeat	Method
CCAGCCCGGCCGGCGATTGAGGCCA	CRISPRCasFinder

spacers of NZ_CP047147_2

>2.1|1553698|55|NZ_CP047147|CRISPRCasFinder
TTCTTTGACCGGCACGGTCACGGCCGGACAGGTCGGGGCGGAGCCCAGCCAAGAA

CRISPR arrays and Neighbor proteins around NZ_CP047147_2

CRISPR arrays

The CRISPR arrays of NZ_CP047147_2

>merge|NZ_CP047147|2|1553673-1553777|CRISPRCasFinder
CCAGCCCGGCCGGCGATTGAGGCCATTCTTTGACCGGCACGGTCACGGCCGGACAGGTCGGGGCGGAGCCCAGCCAAGAACCAGCCCGGCCGGCGCTTGAGGCCA

>NZ_CP047147|2|1|1553673-1553777|CRISPRCasFinder
CCAGCCCGGCCGGCGATTGAGGCCA	TTCTTTGACCGGCACGGTCACGGCCGGACAGGTCGGGGCGGAGCCCAGCCAAGAA
CCAGCCCGGCCGGCGCTTGAGGCCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_159312064.1|1549668_1550649_-|hypothetical-protein	unknown	unknown	gnl|CDD|372624
NZ_CP047147.1|WP_003947594.1|1543092_1543863_-|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|182918
NZ_CP047147.1|WP_159312061.1|1544222_1545167_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|224054
NZ_CP047147.1|WP_008410462.1|1552503_1552869_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|375793
NZ_CP047147.1|WP_159313861.1|1555479_1556706_+|glycine-oxidase-ThiO	unknown	unknown	gnl|CDD|274092
NZ_CP047147.1|WP_159312065.1|1559858_1560725_+|deoxyribonuclease-IV	unknown	unknown	gnl|CDD|214707
NZ_CP047147.1|WP_159313862.1|1557910_1559791_+|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase	unknown	unknown	gnl|CDD|270916
NZ_CP047147.1|WP_008410429.1|1561532_1562012_+|bacterioferritin	unknown	unknown	gnl|CDD|153099
NZ_CP047147.1|WP_003947611.1|1562031_1562271_-|(2Fe-2S)-binding-protein	unknown	unknown	gnl|CDD|377304
NZ_CP047147.1|WP_003947600.1|1550691_1551612_-|methylenetetrahydrofolate-reductase-[NAD(P)H]	unknown	unknown	gnl|CDD|366988
NZ_CP047147.1|WP_159312063.1|1548126_1549626_+|NAD(P)-binding-protein	unknown	unknown	gnl|CDD|224154
NZ_CP047147.1|WP_003947601.1|1551731_1552379_-|thiamine-phosphate-synthase	unknown	unknown	gnl|CDD|234590
NZ_CP047147.1|WP_018895622.1|1556702_1556939_+|sulfur-carrier-protein-ThiS	unknown	unknown	gnl|CDD|273754
NZ_CP047147.1|WP_159313860.1|1554029_1555217_-|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|369639
NZ_CP047147.1|WP_003947612.1|1562718_1564071_-|3-deoxy-7-phosphoheptulonate-synthase-class-II	unknown	unknown	gnl|CDD|366662
NZ_CP047147.1|WP_033239469.1|1560752_1561385_-|sulfite-oxidase-like-oxidoreductase	unknown	unknown	gnl|CDD|239027
NZ_CP047147.1|WP_003947597.1|1547267_1547888_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_CP047147.1|WP_159312062.1|1545138_1547223_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|274414
NZ_CP047147.1|WP_018895623.1|1556941_1557736_+|thiazole-synthase	unknown	unknown	gnl|CDD|234687
NZ_CP047147.1|WP_003947593.1|1542393_1542813_-|DUF3040-domain-containing-protein	unknown	unknown	gnl|CDD|378610

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_159312064.1|1549668_1550649_-|hypothetical-protein	gnl|CDD|372624	pfam13520, AA_permease_2, Amino acid permease.	0.00508526
NZ_CP047147.1|WP_003947594.1|1543092_1543863_-|methyltransferase-domain-containing-protein	gnl|CDD|182918	PRK11036, PRK11036, tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM.	5.48094e-23
NZ_CP047147.1|WP_159312061.1|1544222_1545167_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.40745e-16
NZ_CP047147.1|WP_008410462.1|1552503_1552869_-|helix-turn-helix-domain-containing-protein	gnl|CDD|375793	pfam18367, Rv2175c_C, Rv2175c C-terminal domain of unknown function. This is the C-terminal domain of unknown function found in actinomycetes such as M. tuberculosis Rv2175c. Rv2175c has a DNA binding activity and possesses a winged helix-turn-helix fold, furthermore it is identified as a substrate of the PknL kinase.	5.61182e-30
NZ_CP047147.1|WP_159313861.1|1555479_1556706_+|glycine-oxidase-ThiO	gnl|CDD|274092	TIGR02352, Glycine_oxidase, glycine oxidase ThiO. This family consists of the homotetrameric, FAD-dependent glycine oxidase ThiO, from species such as Bacillus subtilis that use glycine in thiamine biosynthesis. In general, members of this family will not be found in species such as E. coli that instead use tyrosine and the ThiH protein. [Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine].	5.43817e-118
NZ_CP047147.1|WP_159312065.1|1559858_1560725_+|deoxyribonuclease-IV	gnl|CDD|214707	smart00518, AP2Ec, AP endonuclease family 2. These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites.	1.78627e-94
NZ_CP047147.1|WP_159313862.1|1557910_1559791_+|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	6.71956e-111
NZ_CP047147.1|WP_008410429.1|1561532_1562012_+|bacterioferritin	gnl|CDD|153099	cd00907, Bacterioferritin, Bacterioferritin, ferritin-like diiron-binding domain. Bacterioferritins, also known as cytochrome b1, are members of a broad superfamily of ferritin-like diiron-carboxylate proteins. Similar to ferritin in architecture, Bfr forms an oligomer of 24 subunits that assembles to form a hollow sphere with 432 symmetry. Up to 12 heme cofactor groups (iron protoporphyrin IX or coproporphyrin III) are bound between dimer pairs. The role of the heme is unknown, although it may be involved in mediating iron-core reduction and iron release. Each subunit is composed of a four-helix bundle which carries a diiron ferroxidase center; it is here that initial oxidation of ferrous iron by molecular oxygen occurs, facilitating the detoxification of iron, protection against dioxygen and radical products, and storage of ferric-hydroxyphosphate at the core. Some bacterioferritins are composed of two subunit types, one conferring heme-binding ability (alpha) and the other (beta) bestowing ferroxidase activity.	1.27534e-71
NZ_CP047147.1|WP_003947611.1|1562031_1562271_-|(2Fe-2S)-binding-protein	gnl|CDD|377304	pfam04324, Fer2_BFD, BFD-like [2Fe-2S] binding domain. The two Fe ions are each coordinated by two conserved cysteine residues. This domain occurs alone in small proteins such as Bacterioferritin-associated ferredoxin (BFD). The function of BFD is not known, but it may may be a general redox and/or regulatory component involved in the iron storage or mobilisation functions of bacterioferritin in bacteria. This domain is also found in nitrate reductase proteins in association with Nitrite and sulphite reductase 4Fe-4S domain (pfam01077), Nitrite/Sulfite reductase ferredoxin-like half domain (pfam03460) and Pyridine nucleotide-disulphide oxidoreductase (pfam00070). It is also found in NifU nitrogen fixation proteins, in association with NifU-like N terminal domain (pfam01592) and NifU-like domain (pfam01106).	3.21736e-10
NZ_CP047147.1|WP_003947600.1|1550691_1551612_-|methylenetetrahydrofolate-reductase-[NAD(P)H]	gnl|CDD|366988	pfam02219, MTHFR, Methylenetetrahydrofolate reductase. This family includes the 5,10-methylenetetrahydrofolate reductase EC:1.7.99.5 from bacteria and methylenetetrahydrofolate reductase EC: 1.5.1.20 from eukaryotes. The structure for this domain is known to be a TIM barrel.	4.60404e-138
NZ_CP047147.1|WP_159312063.1|1548126_1549626_+|NAD(P)-binding-protein	gnl|CDD|224154	COG1233, COG1233, Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	2.89216e-60
NZ_CP047147.1|WP_003947601.1|1551731_1552379_-|thiamine-phosphate-synthase	gnl|CDD|234590	PRK00043, thiE, thiamine phosphate synthase.	5.62596e-82
NZ_CP047147.1|WP_018895622.1|1556702_1556939_+|sulfur-carrier-protein-ThiS	gnl|CDD|273754	TIGR01683, thiamine_biosynthesis_protein_ThiS, thiamine biosynthesis protein ThiS. This model represents ThiS, a small, ubiquitin-like thiamine biosynthesis protein related to MoaD, a molybdenum cofactor biosynthesis protein. Both proteins are involved in sulfur transfer. ThiS has a conserved Gly-Gly C-terminus that is modified, in reactions requiring ThiI, ThiF, IscS, and a sulfur atom from Cys, into the thiocarboxylate that provides the sulfur for thiazole biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine].	1.80842e-21
NZ_CP047147.1|WP_159313860.1|1554029_1555217_-|FAD-dependent-oxidoreductase	gnl|CDD|369639	pfam07992, Pyr_redox_2, Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.	1.01797e-58
NZ_CP047147.1|WP_003947612.1|1562718_1564071_-|3-deoxy-7-phosphoheptulonate-synthase-class-II	gnl|CDD|366662	pfam01474, DAHP_synth_2, Class-II DAHP synthetase family. Members of this family are aldolase enzymes that catalyze the first step of the shikimate pathway.	0
NZ_CP047147.1|WP_033239469.1|1560752_1561385_-|sulfite-oxidase-like-oxidoreductase	gnl|CDD|239027	cd02109, arch_bact_SO_family_Moco, bacterial and archael members of the sulfite oxidase (SO) family of molybdopterin binding domains. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). Common features of all known members of this family are that they contain one single pterin cofactor and part of the coordination of the metal (Mo) is a cysteine ligand of the protein and that they catalyze the transfer of an oxygen to or from a lone pair of electrons on the substrate. The specific function of this subgroup is unknown.	1.32772e-92
NZ_CP047147.1|WP_003947597.1|1547267_1547888_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.04239e-15
NZ_CP047147.1|WP_159312062.1|1545138_1547223_+|ABC-transporter-permease	gnl|CDD|274414	TIGR03062, hypothetical_protein_lp_1332, YhgE/Pip C-terminal domain. This family contains the C-terminal domain of a family of multiple membrane-spanning proteins of Gram-positive bacteria. One member was shown to be a host protein essential for phage infection, so many members of this family are called "phage infection protein". A separate model, TIGR03061, represents the conserved N-terminal domain. The domains are separated by regions highly variable in both length and sequence, often containing extended heptad repeats as described in model TIGR03057.	3.80163e-90
NZ_CP047147.1|WP_018895623.1|1556941_1557736_+|thiazole-synthase	gnl|CDD|234687	PRK00208, thiG, thiazole synthase; Reviewed.	3.46241e-151
NZ_CP047147.1|WP_003947593.1|1542393_1542813_-|DUF3040-domain-containing-protein	gnl|CDD|378610	pfam11239, DUF3040, Protein of unknown function (DUF3040). Some members in this family of proteins with unknown function are annotated as membrane proteins however this cannot be confirmed.	2.39821e-31

Protein sequences

>NZ_CP047147.1|WP_008410462.1|1552503_1552869_-|helix-turn-helix-domain-containing-protein
MTEIDAKIDALVPEWLTLPDIAEQLDVEVTRVRQLVKDGQLLAVRRGENRVLMVPAAFIDGDKVVKGLSGLLTVLRDDGFADDEMLEWLFTPDETLPGTPAQALNENRGTEVKRRAQALAV
>NZ_CP047147.1|WP_003947601.1|1551731_1552379_-|thiamine-phosphate-synthase
MSDTARARLADARLYLCVDARKRQGDLPEFLDAVLAGGVDIVQLRDKSLEAAEELELLELFADACRRHGRLLAVNDRADVAHAAKADVLHLGQGDLPVPAARAVIGGAPLVGRSTHSEAEAAAAAAQPGVDYFCTGPCWPTPTKPGRHAPGLDLVRYAATLTTDRPWFAIGGIDAANLDEVTEAGARRVVVVRALTEADDPKAAAAGFARRLRAL
>NZ_CP047147.1|WP_003947600.1|1550691_1551612_-|methylenetetrahydrofolate-reductase-[NAD(P)H]
MALGTASTRTDHAATVRDLLASGKTSYSFEFWAPKTPKGERNLWDALRRVEAVAPSFVSVTYGAGGSTRSGTVRATRQIADDTTLTPVAHLTAVNQSVAELRNIIGQYADAGIRNMLAVRGDPPGDPMGEWVRHPEGVTYAAELVRLIKESGDFCVGVAAFPERHPRSADWDTDIRHFVDKCRAGADYAITQMFFDPEDYLRLRDRVTAAGCATPIIPEIMPVTSLRQIERFAQLSNAVFPRKLEERMRASADDPAAVRSMGIEFATEFCARLLAEGVPGLHFITLNNSTATLEIHENLGLHDDKG
>NZ_CP047147.1|WP_159312064.1|1549668_1550649_-|hypothetical-protein
MGWTVLYIAFGIVALWLLGEVLLQYKARLRWRLLAFAGFSCVVLGVLTSLVIVIALGAIAFAVGQTFVTLSFRRGFSTGWAVGGRPGASRRRRTQGATEQDPTLEVSGLQEETPDLPEAPEAPPVYATVEPMPDDTGQYGVYDDGPAKPSTDPAGYETPYAAQESGYAPQDPYAAAQSGYDYDYASQGYGYDTGQGQYTGHADPYAATAGYDQGAQSGYGDWNGQQAQDAYGYPQETYSQTGYTDTPPGGVWVPQQREGESGYDAGYGTYDASGLPPQQQPDGTYVPQQGYDQWQGQGQGYGGQSQEQPPAQGQGAPDHGGQQYRY
>NZ_CP047147.1|WP_159312063.1|1548126_1549626_+|NAD(P)-binding-protein
MARIAVIGAGMGAMAAAARLAVAGHDVEVHERAETYGGALGAYRRDGFAFDTGPGLLTLPAVPRDLFLKTGREALEDRVHLTETDPAVRHVFADGVHADLPHTSRAQVAAALDAALGDGAGQRWGAFLNRARDTWDRSRRPLLEETLWPNWQVLAGREPYPAEPWRRPLRRERRATTLAEIGAWELRDARLAALLGQYALAAGLDPRTAPAGAAVLPYLEQTFGLWSVRGGTRALATALYERCVERKVRFVLGSEVTAIRTEEGRAAGLVTADGTRVDADHVVAGVPPSVLDTLLGAPARTAREVPAQRETDRASRLLVLFALDGERPAGTVHRTVVHSRDAKAEAAHVFGGAPGVAADPTLTVDRPDDPGLVPGPGHEAVTVRLTVAPGTEPTEADLDRITARAEAAVPGLAGRMRWRHALTPADIAQATGAPGGAVPAPALAAADGTLLHPANSTRVPGLFTVGGWSHPGGGLPHAGMSGALVAGLIVEGPEFTGST
>NZ_CP047147.1|WP_003947597.1|1547267_1547888_+|TetR/AcrR-family-transcriptional-regulator
MDSSTRRQATRQKLYEAAVTLIAEQGFSATTVDEIAERAGVAKGTVYYNFASKTVLFEELLRHGVGLLTASLRTAEQETAARGGSRVDALDAMIRAGLVFIDRYPAFTQLYVAELWRTNRAWQDTLLVVRREAVAVVEEVLREAVETGELSPEVDIPLTAPALVGMVLVAALDWQSFQRGRSIDDVHAALSLLLQGRVSGVGPARP
>NZ_CP047147.1|WP_159312062.1|1545138_1547223_+|ABC-transporter-permease
MRSPKLAALELKRFGRGRLPAAALVALLLLPLLYGALYLWSFWDPYGRLDRIPVALVNEDRGAKIGKEELRAGDDITEGLHESEVFQWHEVGGDEARRGVEDGTYYLSLTMPKDFSERIASSSGDHPETSALKVETNDANNYIVGQISRTVFTEVRTSASAKASRSFLDRIFLSFSDIHGATAEAADGADELKRGIGKAKDGSKDLVDGLKETRTGSTDLASGVKRLDKGAGDLEKGSAQVAAGTRLLASKVNSTSAKVQPYLKKDGKFIGDTARLVADSTKIVRANLAELVKAAPVAARSAHAASETLDKVYAARCEDGPGELGDPACPDLKKAKDAAADVAKVADDLETVIGDADLATLDGHLATLQKQADALAKSAPTLGDDLKEAVTKVNALDKGAQQVAAGAKKLHTGLGTARTGASDLDTGIGKVQTGAKDLNGGMFRLADGSGQLAGGLHDGVEKIPDYDKKDRDDRTEVMADPVRLASQSMHAAPNYGTGFAPYFIPLSLWVGAMVAYMVIPPLSRRALAVGTSAWRTALSGWLPVAGLGVLQVAALMSVLHWGLGLEMVRAAGTIGFLVLVSACFTAIVQWLNARFGAAGRILVLAVLMLQLTSAGGTYPVQTSPGFFNAIHPFLPMTYVVEALRLLITGGPLGPVWQACAVLAAFTAGALALTALAARGRQRWTVDRLHPELTL
>NZ_CP047147.1|WP_159312061.1|1544222_1545167_+|ATP-binding-cassette-domain-containing-protein
MTRHQPEPEPERQPEPDAGRDPAAPAGRATPAPDPAELPGGAAVEAERIGLKGPRGWVFREVTVEAAPGSVVALTGASGTGRTCLLLALTGRMKLTEGEARIGGLRLRKQAAAIRRTAALAHVPGVDDLEPSLTVGEHLRERVLLQRRYGTAPLAALKAALRSPRQRRADARRVHDEALAAAGLDLATLPKGPRTAVRDLERLERLRLCVALALIGRPRLIAVDDVDLKLSAPLREEAWALLASVAASGVTVLAVCGEAPAGLPGDVPLVVVVTDRATGARTAEDAPAEPAPKTDDTDETEKETADALAETGRA
>NZ_CP047147.1|WP_003947594.1|1543092_1543863_-|methyltransferase-domain-containing-protein
MSDPMRPRASLRTAVVWEVLKDALDRQVKTTGRRSLDVLDSGGGSGNFAVPVARLGHRVTVVDPSPNALFALERRAAEAGVADLVTGVQGDALGLFDVVDRGAYDAVLLHGVLEHMDDPAEGVASVAAALRPSGTLSLLAAGLGGAVLARALAGHFTEARTALGDPAGRWGEADPVPHRFTPDQLTGLVEAAGVRVGAVHGVRVFADLVPGVLVDTEPGALEALLKLEAAAAEEPAFHAVATQLHVLGEKTPTQED
>NZ_CP047147.1|WP_003947593.1|1542393_1542813_-|DUF3040-domain-containing-protein
MPLSEHEQRMLEQMERALYAEDPKFATALEGSKLRTYTRRRVYQAVVGFLVGIVLLMAGMVAQQIWVSVVGFLVMLGCAVLAVTGWRKAPKPGEQPAPGSADPAGAGAKRRQGRQGRQRRSVMNRIEQRWQQRRDGQGQ
>NZ_CP047147.1|WP_159313860.1|1554029_1555217_-|FAD-dependent-oxidoreductase
MVVVGAGMAGVQTAVALREQGYEGPVTLLGAEPHPPYDRPPLSKAVLLGTAQGSAFDVDFEGLGIGLRLGVAVTGVRPAAHLVDTDAGPVPYTALVLATGAEPLALPGTQDHPAVHLLRTLDDATRLRPVLADRRTVVVVGAGWIGAEFATAAREAGCHVTVVEAAERPLAGALPPEAAEPMAAWYAEQGVELLTGVAVSRVEDHGVRLADGRLLPADAVVVGIGARPATGFLAGSGIALDAHGAVLADGLLRASAPDVYAVGDCASFPSARYGRRLLVHHWDNALQGPRTVAAALTGQEPAPYDPVPYFWSEQFGRFVQYAGHHAPEDLLVHRGDPHAAAWSLCWLSPAGALRAVLTVGRPRDLAQGRKLIASGAPLAPSRVADPTVPLKSTTA
>NZ_CP047147.1|WP_159313861.1|1555479_1556706_+|glycine-oxidase-ThiO
MGPEAVPAAEPAPATAAYSAGGARDVVVAGGGIVGLVTAWRAAQRGLTVTVVDPAPGGGAAQVAAGMLAAVTELHFGEERLLALNLASAERYPAFAAELAEASGQELGYRRCGTLAVALDADDRAYLRELHALQLRSGLESEWLSGRECRRLEPMLAPGVRGGLRVDGDHQIDPRRLASALVTACERAGVVWCRSTAGRLVVRGGRAVGVELADGSLVEGGQTVLAAGSRSGLLAGLPEEVAVPVRPVKGQVVRLAVPEAYRRGAAFLGRTVRAVVRGSHVYLVPRENGELVIGATTEELGWDTTVTAGGVYELLRDAHELVPGLTELPFTEVRAGLRPGSPDNAPLLGPTALPGLHLATGHHRNGVLLTPVTGDVLADVLTTGELPGYADAFTARRFEAAPVQEGAR
>NZ_CP047147.1|WP_018895622.1|1556702_1556939_+|sulfur-carrier-protein-ThiS
MTAEGTRSEAGTYAVSVNGERRELAAGTTLEALVAELSSAPRGVAAAVNEAVVPRGAWTATVLGEGDRVEVLTAVQGG
>NZ_CP047147.1|WP_018895623.1|1556941_1557736_+|thiazole-synthase
MADDTFTIGGTEFGSRLIMGTGGAPSLEVLERALTASGTTLTTVAMRRLDPGVAGSVLSVLERLAIQVLPNTAGCYTAGEAVLTARLAREALGTDLVKLEVVADERTLLPDPVETLEAAEVLVDDGFTVLPYTNDDPVVARRLEEAGCAAVMPLGSPIGSGLGIRNPHNFELIVERAQVPVILDAGAGTASDAALAMELGCAGVMLASAVTRAQEPELMASAMRHAVEAGRLAYRAGRIPRRHFARASSPVEGVAHLDPERPAF
>NZ_CP047147.1|WP_159313862.1|1557910_1559791_+|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase
MLDGRYRVDALIAVGGMATVYRALDTRLDRVVALKVMHPELAADASFVERFIREARSVARLSHPNVVGVFDQGAEGAYVYLAMEYVPGCTLRDVLRERGALTPRAALDVLEPVLAALGAAHRAGFVHRDMKPENVLIGDDGRVKVADFGLVKAVDTVTNTTGAVLGTVSYLAPEQIEQDDVADARVDVYACGVVLYEMLTGGRPHSGDSPAQVLYRHLNEDVPPPSAAVPHLGPELDRLVAVATSRAPEGRPEDAVALLALARDARAALDDAALDAVPPAALEGDRSIAEDRTSVIPRFSTPARPADDDGVQRTSVLAAAPPEPPAPSPRRRLGNRRKGGLAALVAVLLVLCVGAGVWYINSGQFTRVPPLLAKTEDEARQRLTDAGLKVGGVDKAYSDTADRGTVTKTDPGTGERVRGNGSVDLTVSLGPRKVTVPRVEGMALDKAKARLRDAGLEPGMVTRAFSDSVAKGEVVSTDPSAGTERRGGSAVALVVSKGAPVEVPDVAGSSLQEATEALKEAGLKVSTADERVFSEHEKGAVAAQSPKPGTELAEGGEVELTLSKGPDLVEVPDVTGQKEDEARKTLEGAGFKVDVSRWFFGDTVWDQSVEGGETAPRGSEITIRVR
>NZ_CP047147.1|WP_159312065.1|1559858_1560725_+|deoxyribonuclease-IV
MNKSSIGAHIPVAGGLAKTGLAYAQDLAAEAVQVFVANPRGWATPAGDPKQDEEFRRLCAEREIPAYVHAPYLINFGSHTEATAAKSVDSLRHSLRRGREIGALGVVVHTGSATGGRSRETALAQARELMLPLLDELGDEDPYLLLESTAGQGASLCAEAADFGPYFDVLERHPKLGVCLDTCHIHAAGHDLAAPGGVKETLDALVATVGEGRLRLIHANDSKDVAGAHKDRHESIGSGSIGADPFGELLGHPAVAGVPLVIETPGGKEGHTADVARLKELRDAAQGG
>NZ_CP047147.1|WP_033239469.1|1560752_1561385_-|sulfite-oxidase-like-oxidoreductase
MEGMGQPESREAQQPQLPPGQRLQRGWPVTHYGPVPRFRPDRWEFRVFGATAEQGKHTWTHDEFTALPYTTVVADLHCVTKFSMLDAEWGGVLARTVAEAAPPAGHVTHVMVWAEYGFSSNLRLSDFLDERTVFATHKDGELLTAEHGFPLRLIVPHLYAWKGPKWVRGIEYMTADRRGFWEERGYHNVGDPWREQRYSYQEEPGDGPGL
>NZ_CP047147.1|WP_008410429.1|1561532_1562012_+|bacterioferritin
MQGDPEVIEFLNEQLTAELTAINQYWLHYRIQDNNGWYKLAKYTRAESMDEMKHADKLTERILFLDALPNYQRLFHVRVGQTVTEMFEADMQIELEAVDRLKRGIEVMRSKGDHTSRRLFEEILEDEEHHIDYLEAQLAIIEKMGEALYIAQQIEQPDS
>NZ_CP047147.1|WP_003947611.1|1562031_1562271_-|(2Fe-2S)-binding-protein
MNRVYVCSCFGITEEEVRARAAAGAGTPRSIASACKAGTDCGSCVRRIQALLGRGAAPRRHAAGCRAVAGSAAPLDEAA
>NZ_CP047147.1|WP_003947612.1|1562718_1564071_-|3-deoxy-7-phosphoheptulonate-synthase-class-II
MTSTVENSAARVPSWRTLPAAQQPEYPDQEALARVVTELESFPPLVFAGECDQLRARLGAVARGEAFLLQGGDCAESFDGVGADDIRAKVKTLLQMGAVLTYAASVPVVKVGRIAGQYSKPRSKPTETRDGVTLPTYRGDSVNGFDFTEAARVPDPERLKRMYHASASTLNLVRAFTTGGYADLRQVHAWNQDFVKSSPSGQRYEKLAREIDNAMSFMRACGAEPEEFRTVEFYASHEALLLDYETALTRTDSRTGHLYDVSGHMVWIGERTRQMDGAHIEFASKVRNPIGIKLGPTTTPEEALEYIERLDPEREPGRLTFIVRMGADKIRDRLPTLVEKVTASGAQPVWVTDPMHGNTFEAASGHKTRRFDDVLDEVKGFFEVHKELGTHPGGIHVELTGDDVTECVGGGDEIFVDDLHQRYETACDPRLNRSQSLDLAFLVAEMYRGQ

Crispr_ID: NZ_CP047147_3

• CRISPR_ID: NZ_CP047147_3
• CRISPR_location: 1562487-1562631
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP047147_3

Consensus_repeat	Method
AGCCCGGCCGGCGTTTGAGGCCA	CRISPRCasFinder

spacers of NZ_CP047147_3

>3.1|1562510|37|NZ_CP047147|CRISPRCasFinder
CAATTCAAGCCCGGCCGGCGTCTGAGGCCACAACTCA
>3.2|1562570|39|NZ_CP047147|CRISPRCasFinder
TCTTTGACCGGCACGGTCCGGACGAAGCGGACCCACCTC

CRISPR arrays and Neighbor proteins around NZ_CP047147_3

CRISPR arrays

The CRISPR arrays of NZ_CP047147_3

>merge|NZ_CP047147|3|1562487-1562631|CRISPRCasFinder
AGCCCGGCCGGCGTCTGAGGCCACAATTCAAGCCCGGCCGGCGTCTGAGGCCACAACTCAAGCCCGGCCGGCGTTTGAGGCCATCTTTGACCGGCACGGTCCGGACGAAGCGGACCCACCTCAGCCCGGCCGGCGCTTGAGGCCA

>NZ_CP047147|3|2|1562487-1562631|CRISPRCasFinder
AGCCCGGCCGGCGTCTGAGGCCA	CAATTCAAGCCCGGCCGGCGTCTGAGGCCACAACTCA
AGCCCGGCCGGCGTTTGAGGCCA	TCTTTGACCGGCACGGTCCGGACGAAGCGGACCCACCTC
AGCCCGGCCGGCGCTTGAGGCCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_003947611.1|1562031_1562271_-|(2Fe-2S)-binding-protein	unknown	unknown	gnl|CDD|377304
NZ_CP047147.1|WP_159313863.1|1568095_1569304_-|sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
NZ_CP047147.1|WP_008410462.1|1552503_1552869_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|375793
NZ_CP047147.1|WP_159313861.1|1555479_1556706_+|glycine-oxidase-ThiO	unknown	unknown	gnl|CDD|274092
NZ_CP047147.1|WP_159313862.1|1557910_1559791_+|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase	unknown	unknown	gnl|CDD|270916
NZ_CP047147.1|WP_003947617.1|1569421_1570210_-|1-acyl-sn-glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl|CDD|153251
NZ_CP047147.1|WP_003947619.1|1571217_1571832_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_033239469.1|1560752_1561385_-|sulfite-oxidase-like-oxidoreductase	unknown	unknown	gnl|CDD|239027
NZ_CP047147.1|WP_003947618.1|1570436_1571225_+|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|224561
NZ_CP047147.1|WP_159312065.1|1559858_1560725_+|deoxyribonuclease-IV	unknown	unknown	gnl|CDD|214707
NZ_CP047147.1|WP_018895622.1|1556702_1556939_+|sulfur-carrier-protein-ThiS	unknown	unknown	gnl|CDD|273754
NZ_CP047147.1|WP_159312067.1|1566324_1567329_-|2-hydroxyacid-dehydrogenase	unknown	unknown	gnl|CDD|240659
NZ_CP047147.1|WP_159313860.1|1554029_1555217_-|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|369639
NZ_CP047147.1|WP_003947612.1|1562718_1564071_-|3-deoxy-7-phosphoheptulonate-synthase-class-II	unknown	unknown	gnl|CDD|366662
NZ_CP047147.1|WP_008410429.1|1561532_1562012_+|bacterioferritin	unknown	unknown	gnl|CDD|153099
NZ_CP047147.1|WP_018895623.1|1556941_1557736_+|thiazole-synthase	unknown	unknown	gnl|CDD|234687
NZ_CP047147.1|WP_106428967.1|1564122_1564248_+|trp-operon-leader-peptide	unknown	unknown	unknown
NZ_CP047147.1|WP_159312066.1|1564344_1566276_+|phenazine-specific-anthranilate-synthase-component-I	unknown	unknown	gnl|CDD|223225
NZ_CP047147.1|WP_044474559.1|1567385_1568057_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NZ_CP047147.1|WP_026047976.1|1571862_1572645_-|endonuclease	unknown	unknown	gnl|CDD|226098

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_003947611.1|1562031_1562271_-|(2Fe-2S)-binding-protein	gnl|CDD|377304	pfam04324, Fer2_BFD, BFD-like [2Fe-2S] binding domain. The two Fe ions are each coordinated by two conserved cysteine residues. This domain occurs alone in small proteins such as Bacterioferritin-associated ferredoxin (BFD). The function of BFD is not known, but it may may be a general redox and/or regulatory component involved in the iron storage or mobilisation functions of bacterioferritin in bacteria. This domain is also found in nitrate reductase proteins in association with Nitrite and sulphite reductase 4Fe-4S domain (pfam01077), Nitrite/Sulfite reductase ferredoxin-like half domain (pfam03460) and Pyridine nucleotide-disulphide oxidoreductase (pfam00070). It is also found in NifU nitrogen fixation proteins, in association with NifU-like N terminal domain (pfam01592) and NifU-like domain (pfam01106).	3.21736e-10
NZ_CP047147.1|WP_159313863.1|1568095_1569304_-|sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	2.46606e-19
NZ_CP047147.1|WP_008410462.1|1552503_1552869_-|helix-turn-helix-domain-containing-protein	gnl|CDD|375793	pfam18367, Rv2175c_C, Rv2175c C-terminal domain of unknown function. This is the C-terminal domain of unknown function found in actinomycetes such as M. tuberculosis Rv2175c. Rv2175c has a DNA binding activity and possesses a winged helix-turn-helix fold, furthermore it is identified as a substrate of the PknL kinase.	5.61182e-30
NZ_CP047147.1|WP_159313861.1|1555479_1556706_+|glycine-oxidase-ThiO	gnl|CDD|274092	TIGR02352, Glycine_oxidase, glycine oxidase ThiO. This family consists of the homotetrameric, FAD-dependent glycine oxidase ThiO, from species such as Bacillus subtilis that use glycine in thiamine biosynthesis. In general, members of this family will not be found in species such as E. coli that instead use tyrosine and the ThiH protein. [Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine].	5.43817e-118
NZ_CP047147.1|WP_159313862.1|1557910_1559791_+|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	6.71956e-111
NZ_CP047147.1|WP_003947617.1|1569421_1570210_-|1-acyl-sn-glycerol-3-phosphate-acyltransferase	gnl|CDD|153251	cd07989, LPLAT_AGPAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.	2.50788e-48
NZ_CP047147.1|WP_033239469.1|1560752_1561385_-|sulfite-oxidase-like-oxidoreductase	gnl|CDD|239027	cd02109, arch_bact_SO_family_Moco, bacterial and archael members of the sulfite oxidase (SO) family of molybdopterin binding domains. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). Common features of all known members of this family are that they contain one single pterin cofactor and part of the coordination of the metal (Mo) is a cysteine ligand of the protein and that they catalyze the transfer of an oxygen to or from a lone pair of electrons on the substrate. The specific function of this subgroup is unknown.	1.32772e-92
NZ_CP047147.1|WP_003947618.1|1570436_1571225_+|alpha/beta-fold-hydrolase	gnl|CDD|224561	COG1647, COG1647, Esterase/lipase [General function prediction only].	3.0306e-36
NZ_CP047147.1|WP_159312065.1|1559858_1560725_+|deoxyribonuclease-IV	gnl|CDD|214707	smart00518, AP2Ec, AP endonuclease family 2. These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites.	1.78627e-94
NZ_CP047147.1|WP_018895622.1|1556702_1556939_+|sulfur-carrier-protein-ThiS	gnl|CDD|273754	TIGR01683, thiamine_biosynthesis_protein_ThiS, thiamine biosynthesis protein ThiS. This model represents ThiS, a small, ubiquitin-like thiamine biosynthesis protein related to MoaD, a molybdenum cofactor biosynthesis protein. Both proteins are involved in sulfur transfer. ThiS has a conserved Gly-Gly C-terminus that is modified, in reactions requiring ThiI, ThiF, IscS, and a sulfur atom from Cys, into the thiocarboxylate that provides the sulfur for thiazole biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine].	1.80842e-21
NZ_CP047147.1|WP_159312067.1|1566324_1567329_-|2-hydroxyacid-dehydrogenase	gnl|CDD|240659	cd12183, LDH_like_2, D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains. D-Lactate dehydrogenase (LDH) catalyzes the interconversion of pyruvate and lactate, and is a member of the 2-hydroxyacid dehydrogenase family. LDH is homologous to D-2-hydroxyisocaproic acid dehydrogenase (D-HicDH) and shares the 2-domain structure of formate dehydrogenase. D-2-hydroxyisocaproate dehydrogenase-like (HicDH) proteins are NAD-dependent members of the hydroxycarboxylate dehydrogenase family, and share the Rossmann fold typical of many NAD binding proteins. HicDH from Lactobacillus casei forms a monomer and catalyzes the reaction R-CO-COO(-) + NADH + H+ to R-COH-COO(-) + NAD+. D-HicDH, like the structurally distinct L-HicDH, exhibits low side-chain R specificity, accepting a wide range of 2-oxocarboxylic acid side chains. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-adenosylhomocysteine hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain.	0
NZ_CP047147.1|WP_159313860.1|1554029_1555217_-|FAD-dependent-oxidoreductase	gnl|CDD|369639	pfam07992, Pyr_redox_2, Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.	1.01797e-58
NZ_CP047147.1|WP_003947612.1|1562718_1564071_-|3-deoxy-7-phosphoheptulonate-synthase-class-II	gnl|CDD|366662	pfam01474, DAHP_synth_2, Class-II DAHP synthetase family. Members of this family are aldolase enzymes that catalyze the first step of the shikimate pathway.	0
NZ_CP047147.1|WP_008410429.1|1561532_1562012_+|bacterioferritin	gnl|CDD|153099	cd00907, Bacterioferritin, Bacterioferritin, ferritin-like diiron-binding domain. Bacterioferritins, also known as cytochrome b1, are members of a broad superfamily of ferritin-like diiron-carboxylate proteins. Similar to ferritin in architecture, Bfr forms an oligomer of 24 subunits that assembles to form a hollow sphere with 432 symmetry. Up to 12 heme cofactor groups (iron protoporphyrin IX or coproporphyrin III) are bound between dimer pairs. The role of the heme is unknown, although it may be involved in mediating iron-core reduction and iron release. Each subunit is composed of a four-helix bundle which carries a diiron ferroxidase center; it is here that initial oxidation of ferrous iron by molecular oxygen occurs, facilitating the detoxification of iron, protection against dioxygen and radical products, and storage of ferric-hydroxyphosphate at the core. Some bacterioferritins are composed of two subunit types, one conferring heme-binding ability (alpha) and the other (beta) bestowing ferroxidase activity.	1.27534e-71
NZ_CP047147.1|WP_018895623.1|1556941_1557736_+|thiazole-synthase	gnl|CDD|234687	PRK00208, thiG, thiazole synthase; Reviewed.	3.46241e-151
NZ_CP047147.1|WP_159312066.1|1564344_1566276_+|phenazine-specific-anthranilate-synthase-component-I	gnl|CDD|223225	COG0147, TrpE, Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism].	7.02131e-54
NZ_CP047147.1|WP_044474559.1|1567385_1568057_-|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	2.14731e-58
NZ_CP047147.1|WP_026047976.1|1571862_1572645_-|endonuclease	gnl|CDD|226098	COG3568, ElsH, Metal-dependent hydrolase [General function prediction only].	5.60577e-14

Protein sequences

>NZ_CP047147.1|WP_003947611.1|1562031_1562271_-|(2Fe-2S)-binding-protein
MNRVYVCSCFGITEEEVRARAAAGAGTPRSIASACKAGTDCGSCVRRIQALLGRGAAPRRHAAGCRAVAGSAAPLDEAA
>NZ_CP047147.1|WP_008410429.1|1561532_1562012_+|bacterioferritin
MQGDPEVIEFLNEQLTAELTAINQYWLHYRIQDNNGWYKLAKYTRAESMDEMKHADKLTERILFLDALPNYQRLFHVRVGQTVTEMFEADMQIELEAVDRLKRGIEVMRSKGDHTSRRLFEEILEDEEHHIDYLEAQLAIIEKMGEALYIAQQIEQPDS
>NZ_CP047147.1|WP_033239469.1|1560752_1561385_-|sulfite-oxidase-like-oxidoreductase
MEGMGQPESREAQQPQLPPGQRLQRGWPVTHYGPVPRFRPDRWEFRVFGATAEQGKHTWTHDEFTALPYTTVVADLHCVTKFSMLDAEWGGVLARTVAEAAPPAGHVTHVMVWAEYGFSSNLRLSDFLDERTVFATHKDGELLTAEHGFPLRLIVPHLYAWKGPKWVRGIEYMTADRRGFWEERGYHNVGDPWREQRYSYQEEPGDGPGL
>NZ_CP047147.1|WP_159312065.1|1559858_1560725_+|deoxyribonuclease-IV
MNKSSIGAHIPVAGGLAKTGLAYAQDLAAEAVQVFVANPRGWATPAGDPKQDEEFRRLCAEREIPAYVHAPYLINFGSHTEATAAKSVDSLRHSLRRGREIGALGVVVHTGSATGGRSRETALAQARELMLPLLDELGDEDPYLLLESTAGQGASLCAEAADFGPYFDVLERHPKLGVCLDTCHIHAAGHDLAAPGGVKETLDALVATVGEGRLRLIHANDSKDVAGAHKDRHESIGSGSIGADPFGELLGHPAVAGVPLVIETPGGKEGHTADVARLKELRDAAQGG
>NZ_CP047147.1|WP_159313862.1|1557910_1559791_+|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase
MLDGRYRVDALIAVGGMATVYRALDTRLDRVVALKVMHPELAADASFVERFIREARSVARLSHPNVVGVFDQGAEGAYVYLAMEYVPGCTLRDVLRERGALTPRAALDVLEPVLAALGAAHRAGFVHRDMKPENVLIGDDGRVKVADFGLVKAVDTVTNTTGAVLGTVSYLAPEQIEQDDVADARVDVYACGVVLYEMLTGGRPHSGDSPAQVLYRHLNEDVPPPSAAVPHLGPELDRLVAVATSRAPEGRPEDAVALLALARDARAALDDAALDAVPPAALEGDRSIAEDRTSVIPRFSTPARPADDDGVQRTSVLAAAPPEPPAPSPRRRLGNRRKGGLAALVAVLLVLCVGAGVWYINSGQFTRVPPLLAKTEDEARQRLTDAGLKVGGVDKAYSDTADRGTVTKTDPGTGERVRGNGSVDLTVSLGPRKVTVPRVEGMALDKAKARLRDAGLEPGMVTRAFSDSVAKGEVVSTDPSAGTERRGGSAVALVVSKGAPVEVPDVAGSSLQEATEALKEAGLKVSTADERVFSEHEKGAVAAQSPKPGTELAEGGEVELTLSKGPDLVEVPDVTGQKEDEARKTLEGAGFKVDVSRWFFGDTVWDQSVEGGETAPRGSEITIRVR
>NZ_CP047147.1|WP_018895623.1|1556941_1557736_+|thiazole-synthase
MADDTFTIGGTEFGSRLIMGTGGAPSLEVLERALTASGTTLTTVAMRRLDPGVAGSVLSVLERLAIQVLPNTAGCYTAGEAVLTARLAREALGTDLVKLEVVADERTLLPDPVETLEAAEVLVDDGFTVLPYTNDDPVVARRLEEAGCAAVMPLGSPIGSGLGIRNPHNFELIVERAQVPVILDAGAGTASDAALAMELGCAGVMLASAVTRAQEPELMASAMRHAVEAGRLAYRAGRIPRRHFARASSPVEGVAHLDPERPAF
>NZ_CP047147.1|WP_018895622.1|1556702_1556939_+|sulfur-carrier-protein-ThiS
MTAEGTRSEAGTYAVSVNGERRELAAGTTLEALVAELSSAPRGVAAAVNEAVVPRGAWTATVLGEGDRVEVLTAVQGG
>NZ_CP047147.1|WP_159313861.1|1555479_1556706_+|glycine-oxidase-ThiO
MGPEAVPAAEPAPATAAYSAGGARDVVVAGGGIVGLVTAWRAAQRGLTVTVVDPAPGGGAAQVAAGMLAAVTELHFGEERLLALNLASAERYPAFAAELAEASGQELGYRRCGTLAVALDADDRAYLRELHALQLRSGLESEWLSGRECRRLEPMLAPGVRGGLRVDGDHQIDPRRLASALVTACERAGVVWCRSTAGRLVVRGGRAVGVELADGSLVEGGQTVLAAGSRSGLLAGLPEEVAVPVRPVKGQVVRLAVPEAYRRGAAFLGRTVRAVVRGSHVYLVPRENGELVIGATTEELGWDTTVTAGGVYELLRDAHELVPGLTELPFTEVRAGLRPGSPDNAPLLGPTALPGLHLATGHHRNGVLLTPVTGDVLADVLTTGELPGYADAFTARRFEAAPVQEGAR
>NZ_CP047147.1|WP_159313860.1|1554029_1555217_-|FAD-dependent-oxidoreductase
MVVVGAGMAGVQTAVALREQGYEGPVTLLGAEPHPPYDRPPLSKAVLLGTAQGSAFDVDFEGLGIGLRLGVAVTGVRPAAHLVDTDAGPVPYTALVLATGAEPLALPGTQDHPAVHLLRTLDDATRLRPVLADRRTVVVVGAGWIGAEFATAAREAGCHVTVVEAAERPLAGALPPEAAEPMAAWYAEQGVELLTGVAVSRVEDHGVRLADGRLLPADAVVVGIGARPATGFLAGSGIALDAHGAVLADGLLRASAPDVYAVGDCASFPSARYGRRLLVHHWDNALQGPRTVAAALTGQEPAPYDPVPYFWSEQFGRFVQYAGHHAPEDLLVHRGDPHAAAWSLCWLSPAGALRAVLTVGRPRDLAQGRKLIASGAPLAPSRVADPTVPLKSTTA
>NZ_CP047147.1|WP_008410462.1|1552503_1552869_-|helix-turn-helix-domain-containing-protein
MTEIDAKIDALVPEWLTLPDIAEQLDVEVTRVRQLVKDGQLLAVRRGENRVLMVPAAFIDGDKVVKGLSGLLTVLRDDGFADDEMLEWLFTPDETLPGTPAQALNENRGTEVKRRAQALAV
>NZ_CP047147.1|WP_003947612.1|1562718_1564071_-|3-deoxy-7-phosphoheptulonate-synthase-class-II
MTSTVENSAARVPSWRTLPAAQQPEYPDQEALARVVTELESFPPLVFAGECDQLRARLGAVARGEAFLLQGGDCAESFDGVGADDIRAKVKTLLQMGAVLTYAASVPVVKVGRIAGQYSKPRSKPTETRDGVTLPTYRGDSVNGFDFTEAARVPDPERLKRMYHASASTLNLVRAFTTGGYADLRQVHAWNQDFVKSSPSGQRYEKLAREIDNAMSFMRACGAEPEEFRTVEFYASHEALLLDYETALTRTDSRTGHLYDVSGHMVWIGERTRQMDGAHIEFASKVRNPIGIKLGPTTTPEEALEYIERLDPEREPGRLTFIVRMGADKIRDRLPTLVEKVTASGAQPVWVTDPMHGNTFEAASGHKTRRFDDVLDEVKGFFEVHKELGTHPGGIHVELTGDDVTECVGGGDEIFVDDLHQRYETACDPRLNRSQSLDLAFLVAEMYRGQ
>NZ_CP047147.1|WP_106428967.1|1564122_1564248_+|trp-operon-leader-peptide
MGRATHCHASAPGGGGGCATIRPMTAQQTQNWWWTAHPAAR
>NZ_CP047147.1|WP_159312066.1|1564344_1566276_+|phenazine-specific-anthranilate-synthase-component-I
MSPTSPTPPEAPFDLSRLTAPDAPPFALLRRSAPGLDGRTVEVLTGPVREVDHLADLPVDERPALALVPFRQIRERGFDVRDDATGLVVLHADAVHRMPVEEALAALPAHPVEVADGGFDLGDGAYEEVVRRVVADEIGGGEGANFVISRTWEGRIEGYAPADALALFRRLLDQERGAYWTYVVHTGERTLVGASPEVHVRMSGGGRDEAGGTVVMNPISGTYRYPAEGPTAQGLLDFLDDAKERDELSMVVDEELKMMCAVGDLGGVVVGPRLKEMAHLAHTEYELRGRSTLDVREVLRQTMFAATVTGSPVQNACRVIERYEPGGRGYYAGALALLSADASGAQSLDSPILIRTADVDAAGLVKVRVGATLVRGSDPAGEVAETHAKAAGVLAALGVRPARPKAGPAPVRFADDIRVRAALDARRERLSPFWLRMREPVAPVAGEALVVDAEDTFTSMLAHVLRAAGHRTTVRRFDEPGLREAVAAHRGTVVLGPGPGDPSDPADPRMRLLREVTAEVLDARHGGRGVLGVCLGHELIAAELGLPLVRKRVPYQGAQVAIDLFGRWETVGFYNSYVASCDDEAATELAAHGVEVSRDAAGEVHALRGPGFASVQFHPESVLSLRGPALVAELLAGVPVETG
>NZ_CP047147.1|WP_159312067.1|1566324_1567329_-|2-hydroxyacid-dehydrogenase
MEILAFGVQDDERPLIERAFAGEHEVRCVDVFLNRDTAAIARGYEAISTSVNADLGGPVLQTLAAGGTQFIAQRSTGFNNIDLDVAERLALTVARVSSYSPYSVAEFAWTLAMAVNRRIVRAANRTRDFDFRLEGLMGRDLRGRTVGVIGTGRIGEAFTRIAHGFGMNLLGWDIAENPACRELGMRYVEREELFRESDVVSLHVPLLPATEHLVDAHALDLMKDDAILVNSSRGGLVDTRALVDVLRAGRLLGVGLDVYEAEAGLFFYDKSLDVVTDDVLARLMTFPNVVVTSHQAYYTEDAVTEIIDTTVRNVRDYVAGRRSENVLVPALPPR
>NZ_CP047147.1|WP_044474559.1|1567385_1568057_-|response-regulator-transcription-factor
MVVDDHPMWRDAVARDLAEAGFAVVATAGDGPQAVRRARATRPDVLVLDLNLPGLPGARVCQEVAGEDGPRVLVLSASGEHTDVLEAVKAGATGYLVKSAGTEELIDAVHRTARGDAVFTPGLAGLVLGEYRRLAAGPAPTRGKPDAPRLTARETEVLRLVAKGLSYKQIAERLVISHRTVQNHVQNTLGKLQLHNRVELVRYAIEAGLDEEDEAEGTPGAER
>NZ_CP047147.1|WP_159313863.1|1568095_1569304_-|sensor-histidine-kinase
MSVEQPLWRALTAYRALTAVYAVAIAVVARDSYERPQVAFGYLAVLLVWTLATLPRFTGAARCTRPFLAVDTGLALAGILLTPLADGAGRHAADGPTLPSIWTAGAVLACALKGGWRWAAAASTLVGAANLAQRGEASPNTLHNVLLVWVAAIAIGYVVEVARASERTLARALEIQAATRERERLARDIHDGVLQVLAMVQRRGTAVGGEAAELGRLAGEQEAALRRLITQGPVPEPRTAAGPDAAPEDDTRPQDLMALLGRYADARVTLSGPGTQVELAPHAARETAAAVGAALDNVRTHVGPGARAWVLVEDEPDQVLVSVRDEGPGIPEGRLAEAAEEGRLGVAQSIRGRLRDLGGTAELVSVPGQGTEVELTVPKQDQGGGEAATGRRYPARTGEGTQ
>NZ_CP047147.1|WP_003947617.1|1569421_1570210_-|1-acyl-sn-glycerol-3-phosphate-acyltransferase
MIYGAMKVVIGGPLKVAFRPWVEGIENIPADGPAILASNHLSFSDSFFLPTMLDRKVTFIAKAEYFTTPGVKGRMTAAFFKGVGQLPVDRSGGRGAGEAAIRSGIEVLERGELFGIYPEGTRSPDGRLYRGKPGGLARVALATGAPVIPVAMIDTEKIQPPGQVRPKLMRPGIRIGKPLDFRRYEGMDHDRFVLRAVTDEVMYEIMKLSGQEYVDVYATVAKRQMAEDAKKRAEEEKAIAKAEKAAAKAATAREQDDSGRAA
>NZ_CP047147.1|WP_003947618.1|1570436_1571225_+|alpha/beta-fold-hydrolase
MPVLPGAEPYRHDGGPTGVLLCHGFTGTPQSMRPWAEDLAARGHTVSLPLLPGHGTRWEDLQLTGWQDWYAEVDRALGELLARCERVYVAGLSMGGALALRLAARHGDAVRGVVVVNPANKVHGLSAYALPAARHLVRTTKGLVSDIALEGSEEVGYHRVPLHAAHSLRNFFRLVDAELPQVTQPLLLLRSPRDHVVPPADSARVLGRVSSRDVTEILLQNSFHVATLDHDAPRVFEESAAFLARTGADGADSRPEGEAVSG
>NZ_CP047147.1|WP_003947619.1|1571217_1571832_+|hypothetical-protein
MAEQGAGREENCEPDEQKPPLDEKAAWEAIVAGYGDEPADPPGARPFKSVEEMADLDRELPSVTPDPAGGTDTLEPERPPLGGSVSFAPGIGPRDYRLAEENTPAGKDGKGARKGGAAEDDDEGHFVPPEPPPLPEADTTTRFAWVAVLGGPLLLLLAVLLDWDMTWWLTTLGVGGFLGGFATLVVRMNDGDEDEDDPGRGAVV
>NZ_CP047147.1|WP_026047976.1|1571862_1572645_-|endonuclease
MVRVGPGELPASGRVGGDVVVRVLSYNVRSLRDDPAAVARVVRACAPDLVLVQEAPRFFRWRKPLGRLAAASGLVVLGGGAPAAGPALLCSLRAGVESVHDELLPLTPGLHRRGFSTAVVRFGTVRLGVLSCHLSLQKDERYAQGGMVLERLAALGVEHAVAGGDINERPKGRTFRRLAAELQDGWAVRPWGGEYTSTPADPHQRIDAVFATPGIEVLGCGVPAPGTAAPGVPPFTEDDLVRATDHLPVLAALRVPGTGR

Crispr_ID: NZ_CP047147_4

• CRISPR_ID: NZ_CP047147_4
• CRISPR_location: 1572791-1572935
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP047147_4

Consensus_repeat	Method
AGCCCGGCCGGCGTTTGAGGCCA	CRISPRCasFinder

spacers of NZ_CP047147_4

>4.1|1572814|37|NZ_CP047147|CRISPRCasFinder
CACTTCAAGCCCGGCCGGCGCTTGAGGCCACACTTCA
>4.2|1572874|39|NZ_CP047147|CRISPRCasFinder
TCGGTGACCGGCGCCGATAGCCGGACCGCACCCGACCGA

CRISPR arrays and Neighbor proteins around NZ_CP047147_4

CRISPR arrays

The CRISPR arrays of NZ_CP047147_4

>merge|NZ_CP047147|4|1572791-1572935|CRISPRCasFinder
AGCCCGGCCGGCGTTTGAGGCCACACTTCAAGCCCGGCCGGCGCTTGAGGCCACACTTCAAGCCCGGCCGGCGTTTGAGGCCATCGGTGACCGGCGCCGATAGCCGGACCGCACCCGACCGAAGCCCGGCCGGCGCCCGAGGCAA

>NZ_CP047147|4|3|1572791-1572935|CRISPRCasFinder
AGCCCGGCCGGCGTTTGAGGCCA	CACTTCAAGCCCGGCCGGCGCTTGAGGCCACACTTCA
AGCCCGGCCGGCGTTTGAGGCCA	TCGGTGACCGGCGCCGATAGCCGGACCGCACCCGACCGA
AGCCCGGCCGGCGCCCGAGGCAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_008413322.1|1576411_1577182_-|metallophosphoesterase	unknown	unknown	gnl|CDD|277338
NZ_CP047147.1|WP_003947621.1|1572990_1573932_-|ROK-family-glucokinase	unknown	unknown	gnl|CDD|273246
NZ_CP047147.1|WP_159312070.1|1581861_1583046_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159313863.1|1568095_1569304_-|sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
NZ_CP047147.1|WP_003947617.1|1569421_1570210_-|1-acyl-sn-glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl|CDD|153251
NZ_CP047147.1|WP_030769006.1|1579348_1580491_-|glycosyltransferase-family-4-protein	unknown	unknown	gnl|CDD|340831
NZ_CP047147.1|WP_015508015.1|1583085_1584060_-|C40-family-peptidase	unknown	unknown	gnl|CDD|366353
NZ_CP047147.1|WP_003947619.1|1571217_1571832_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_003947618.1|1570436_1571225_+|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|224561
NZ_CP047147.1|WP_018470628.1|1574577_1575768_-|hypothetical-protein	unknown	unknown	gnl|CDD|223082
NZ_CP047147.1|WP_159312068.1|1574012_1574501_-|hypothetical-protein	unknown	unknown	gnl|CDD|375065
NZ_CP047147.1|WP_003947612.1|1562718_1564071_-|3-deoxy-7-phosphoheptulonate-synthase-class-II	unknown	unknown	gnl|CDD|366662
NZ_CP047147.1|WP_003947626.1|1577461_1579258_+|long-chain-fatty-acid--CoA-ligase	unknown	unknown	gnl|CDD|341233
NZ_CP047147.1|WP_159312067.1|1566324_1567329_-|2-hydroxyacid-dehydrogenase	unknown	unknown	gnl|CDD|240659
NZ_CP047147.1|WP_106428967.1|1564122_1564248_+|trp-operon-leader-peptide	unknown	unknown	unknown
NZ_CP047147.1|WP_159312069.1|1580609_1581905_+|DUF2029-domain-containing-protein	unknown	unknown	gnl|CDD|378217
NZ_CP047147.1|WP_003947624.1|1575815_1576262_-|SRPBCC-family-protein	unknown	unknown	gnl|CDD|176861
NZ_CP047147.1|WP_159312066.1|1564344_1566276_+|phenazine-specific-anthranilate-synthase-component-I	unknown	unknown	gnl|CDD|223225
NZ_CP047147.1|WP_044474559.1|1567385_1568057_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NZ_CP047147.1|WP_026047976.1|1571862_1572645_-|endonuclease	unknown	unknown	gnl|CDD|226098

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_008413322.1|1576411_1577182_-|metallophosphoesterase	gnl|CDD|277338	cd07392, MPP_PAE1087, Pyrobaculum aerophilum PAE1087 and related proteins, metallophosphatase domain. PAE1087 is an uncharacterized Pyrobaculum aerophilum protein with a metallophosphatase domain. The domain present in members of this family belongs to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	8.8512e-18
NZ_CP047147.1|WP_003947621.1|1572990_1573932_-|ROK-family-glucokinase	gnl|CDD|273246	TIGR00744, Glucokinase_Glucose_kinase., ROK family protein (putative glucokinase). This model models one branch of the ROK superfamily of proteins. The three members of the seed alignment for this model all have experimental evidence for activity as glucokinase, but the set of related proteins is crowded with paralogs of different or unknown function. Proteins scoring above the trusted_cutoff will show strong similarity to at least one known glucokinase and may be designated as putative glucokinases. However, definitive identification of glucokinases should be done only with extreme caution. [Unknown function, General].	6.22919e-142
NZ_CP047147.1|WP_159313863.1|1568095_1569304_-|sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	2.46606e-19
NZ_CP047147.1|WP_003947617.1|1569421_1570210_-|1-acyl-sn-glycerol-3-phosphate-acyltransferase	gnl|CDD|153251	cd07989, LPLAT_AGPAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.	2.50788e-48
NZ_CP047147.1|WP_030769006.1|1579348_1580491_-|glycosyltransferase-family-4-protein	gnl|CDD|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	6.28641e-70
NZ_CP047147.1|WP_015508015.1|1583085_1584060_-|C40-family-peptidase	gnl|CDD|366353	pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.	2.31777e-35
NZ_CP047147.1|WP_003947618.1|1570436_1571225_+|alpha/beta-fold-hydrolase	gnl|CDD|224561	COG1647, COG1647, Esterase/lipase [General function prediction only].	3.0306e-36
NZ_CP047147.1|WP_018470628.1|1574577_1575768_-|hypothetical-protein	gnl|CDD|223082	COG0003, ArsA, Predicted ATPase involved in chromosome partitioning [Cell division and chromosome partitioning].	1.08088e-37
NZ_CP047147.1|WP_159312068.1|1574012_1574501_-|hypothetical-protein	gnl|CDD|375065	pfam17230, DUF5304, Family of unknown function (DUF5304). This family of unknown function is found in Actinobacteria.	2.16783e-48
NZ_CP047147.1|WP_003947612.1|1562718_1564071_-|3-deoxy-7-phosphoheptulonate-synthase-class-II	gnl|CDD|366662	pfam01474, DAHP_synth_2, Class-II DAHP synthetase family. Members of this family are aldolase enzymes that catalyze the first step of the shikimate pathway.	0
NZ_CP047147.1|WP_003947626.1|1577461_1579258_+|long-chain-fatty-acid--CoA-ligase	gnl|CDD|341233	cd05907, VL_LC_FACS_like, Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases. This family includes long-chain fatty acid (C12-C20) CoA synthetases and Bubblegum-like very long-chain (>C20) fatty acid CoA synthetases. FACS catalyzes the formation of fatty acyl-CoA in a two-step reaction: the formation of a fatty acyl-AMP molecule as an intermediate, and the formation of a fatty acyl-CoA. Eukaryotes generally have multiple isoforms of LC-FACS genes with multiple splice variants. For example, nine genes are found in Arabidopsis and six genes are expressed in mammalian cells. Drosophila melanogaster mutant bubblegum (BGM) have elevated levels of very-long-chain fatty acids (VLCFA) caused by a defective gene later named bubblegum. The human homolog (hsBG) of bubblegum has been characterized as a very long chain fatty acid CoA synthetase that functions specifically in the brain; hsBG may play a central role in brain VLCFA metabolism and myelinogenesis. Free fatty acids must be "activated" to their CoA thioesters before participating in most catabolic and anabolic reactions.	0
NZ_CP047147.1|WP_159312067.1|1566324_1567329_-|2-hydroxyacid-dehydrogenase	gnl|CDD|240659	cd12183, LDH_like_2, D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains. D-Lactate dehydrogenase (LDH) catalyzes the interconversion of pyruvate and lactate, and is a member of the 2-hydroxyacid dehydrogenase family. LDH is homologous to D-2-hydroxyisocaproic acid dehydrogenase (D-HicDH) and shares the 2-domain structure of formate dehydrogenase. D-2-hydroxyisocaproate dehydrogenase-like (HicDH) proteins are NAD-dependent members of the hydroxycarboxylate dehydrogenase family, and share the Rossmann fold typical of many NAD binding proteins. HicDH from Lactobacillus casei forms a monomer and catalyzes the reaction R-CO-COO(-) + NADH + H+ to R-COH-COO(-) + NAD+. D-HicDH, like the structurally distinct L-HicDH, exhibits low side-chain R specificity, accepting a wide range of 2-oxocarboxylic acid side chains. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-adenosylhomocysteine hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain.	0
NZ_CP047147.1|WP_159312069.1|1580609_1581905_+|DUF2029-domain-containing-protein	gnl|CDD|378217	pfam09594, GT87, Glycosyltransferase family 87. The enzymes in this family are glycosyltransferases. PimE is involved in phosphatidylinositol mannoside (PIM) synthesis, a major class of glycolipids in all mycobacteria. PimE is a polyprenol-phosphate-mannose-dependent mannosyltransferase that transfers the fifth mannose of PIM. The family also includes alpha(1-->3) arabinofuranosyltransferase, invloved in the synthesis of of mycobacterial arabinogalactan.	1.66397e-06
NZ_CP047147.1|WP_003947624.1|1575815_1576262_-|SRPBCC-family-protein	gnl|CDD|176861	cd07819, SRPBCC_2, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins. Uncharacterized group of the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands. SRPBCC domains include the steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domains of mammalian STARD1-STARD15, the C-terminal catalytic domains of the alpha oxygenase subunit of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases (RHOs_alpha_C), Class I and II phosphatidylinositol transfer proteins (PITPs), Bet v 1 (the major pollen allergen of white birch, Betula verrucosa), CoxG, CalC, and related proteins. Other members of the superfamily include PYR/PYL/RCAR plant proteins, the aromatase/cyclase (ARO/CYC) domains of proteins such as Streptomyces glaucescens tetracenomycin, and the SRPBCC domains of Streptococcus mutans Smu.440 and related proteins.	4.00255e-55
NZ_CP047147.1|WP_159312066.1|1564344_1566276_+|phenazine-specific-anthranilate-synthase-component-I	gnl|CDD|223225	COG0147, TrpE, Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism].	7.02131e-54
NZ_CP047147.1|WP_044474559.1|1567385_1568057_-|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	2.14731e-58
NZ_CP047147.1|WP_026047976.1|1571862_1572645_-|endonuclease	gnl|CDD|226098	COG3568, ElsH, Metal-dependent hydrolase [General function prediction only].	5.60577e-14

Protein sequences

>NZ_CP047147.1|WP_026047976.1|1571862_1572645_-|endonuclease
MVRVGPGELPASGRVGGDVVVRVLSYNVRSLRDDPAAVARVVRACAPDLVLVQEAPRFFRWRKPLGRLAAASGLVVLGGGAPAAGPALLCSLRAGVESVHDELLPLTPGLHRRGFSTAVVRFGTVRLGVLSCHLSLQKDERYAQGGMVLERLAALGVEHAVAGGDINERPKGRTFRRLAAELQDGWAVRPWGGEYTSTPADPHQRIDAVFATPGIEVLGCGVPAPGTAAPGVPPFTEDDLVRATDHLPVLAALRVPGTGR
>NZ_CP047147.1|WP_003947619.1|1571217_1571832_+|hypothetical-protein
MAEQGAGREENCEPDEQKPPLDEKAAWEAIVAGYGDEPADPPGARPFKSVEEMADLDRELPSVTPDPAGGTDTLEPERPPLGGSVSFAPGIGPRDYRLAEENTPAGKDGKGARKGGAAEDDDEGHFVPPEPPPLPEADTTTRFAWVAVLGGPLLLLLAVLLDWDMTWWLTTLGVGGFLGGFATLVVRMNDGDEDEDDPGRGAVV
>NZ_CP047147.1|WP_003947618.1|1570436_1571225_+|alpha/beta-fold-hydrolase
MPVLPGAEPYRHDGGPTGVLLCHGFTGTPQSMRPWAEDLAARGHTVSLPLLPGHGTRWEDLQLTGWQDWYAEVDRALGELLARCERVYVAGLSMGGALALRLAARHGDAVRGVVVVNPANKVHGLSAYALPAARHLVRTTKGLVSDIALEGSEEVGYHRVPLHAAHSLRNFFRLVDAELPQVTQPLLLLRSPRDHVVPPADSARVLGRVSSRDVTEILLQNSFHVATLDHDAPRVFEESAAFLARTGADGADSRPEGEAVSG
>NZ_CP047147.1|WP_003947617.1|1569421_1570210_-|1-acyl-sn-glycerol-3-phosphate-acyltransferase
MIYGAMKVVIGGPLKVAFRPWVEGIENIPADGPAILASNHLSFSDSFFLPTMLDRKVTFIAKAEYFTTPGVKGRMTAAFFKGVGQLPVDRSGGRGAGEAAIRSGIEVLERGELFGIYPEGTRSPDGRLYRGKPGGLARVALATGAPVIPVAMIDTEKIQPPGQVRPKLMRPGIRIGKPLDFRRYEGMDHDRFVLRAVTDEVMYEIMKLSGQEYVDVYATVAKRQMAEDAKKRAEEEKAIAKAEKAAAKAATAREQDDSGRAA
>NZ_CP047147.1|WP_159313863.1|1568095_1569304_-|sensor-histidine-kinase
MSVEQPLWRALTAYRALTAVYAVAIAVVARDSYERPQVAFGYLAVLLVWTLATLPRFTGAARCTRPFLAVDTGLALAGILLTPLADGAGRHAADGPTLPSIWTAGAVLACALKGGWRWAAAASTLVGAANLAQRGEASPNTLHNVLLVWVAAIAIGYVVEVARASERTLARALEIQAATRERERLARDIHDGVLQVLAMVQRRGTAVGGEAAELGRLAGEQEAALRRLITQGPVPEPRTAAGPDAAPEDDTRPQDLMALLGRYADARVTLSGPGTQVELAPHAARETAAAVGAALDNVRTHVGPGARAWVLVEDEPDQVLVSVRDEGPGIPEGRLAEAAEEGRLGVAQSIRGRLRDLGGTAELVSVPGQGTEVELTVPKQDQGGGEAATGRRYPARTGEGTQ
>NZ_CP047147.1|WP_044474559.1|1567385_1568057_-|response-regulator-transcription-factor
MVVDDHPMWRDAVARDLAEAGFAVVATAGDGPQAVRRARATRPDVLVLDLNLPGLPGARVCQEVAGEDGPRVLVLSASGEHTDVLEAVKAGATGYLVKSAGTEELIDAVHRTARGDAVFTPGLAGLVLGEYRRLAAGPAPTRGKPDAPRLTARETEVLRLVAKGLSYKQIAERLVISHRTVQNHVQNTLGKLQLHNRVELVRYAIEAGLDEEDEAEGTPGAER
>NZ_CP047147.1|WP_159312067.1|1566324_1567329_-|2-hydroxyacid-dehydrogenase
MEILAFGVQDDERPLIERAFAGEHEVRCVDVFLNRDTAAIARGYEAISTSVNADLGGPVLQTLAAGGTQFIAQRSTGFNNIDLDVAERLALTVARVSSYSPYSVAEFAWTLAMAVNRRIVRAANRTRDFDFRLEGLMGRDLRGRTVGVIGTGRIGEAFTRIAHGFGMNLLGWDIAENPACRELGMRYVEREELFRESDVVSLHVPLLPATEHLVDAHALDLMKDDAILVNSSRGGLVDTRALVDVLRAGRLLGVGLDVYEAEAGLFFYDKSLDVVTDDVLARLMTFPNVVVTSHQAYYTEDAVTEIIDTTVRNVRDYVAGRRSENVLVPALPPR
>NZ_CP047147.1|WP_159312066.1|1564344_1566276_+|phenazine-specific-anthranilate-synthase-component-I
MSPTSPTPPEAPFDLSRLTAPDAPPFALLRRSAPGLDGRTVEVLTGPVREVDHLADLPVDERPALALVPFRQIRERGFDVRDDATGLVVLHADAVHRMPVEEALAALPAHPVEVADGGFDLGDGAYEEVVRRVVADEIGGGEGANFVISRTWEGRIEGYAPADALALFRRLLDQERGAYWTYVVHTGERTLVGASPEVHVRMSGGGRDEAGGTVVMNPISGTYRYPAEGPTAQGLLDFLDDAKERDELSMVVDEELKMMCAVGDLGGVVVGPRLKEMAHLAHTEYELRGRSTLDVREVLRQTMFAATVTGSPVQNACRVIERYEPGGRGYYAGALALLSADASGAQSLDSPILIRTADVDAAGLVKVRVGATLVRGSDPAGEVAETHAKAAGVLAALGVRPARPKAGPAPVRFADDIRVRAALDARRERLSPFWLRMREPVAPVAGEALVVDAEDTFTSMLAHVLRAAGHRTTVRRFDEPGLREAVAAHRGTVVLGPGPGDPSDPADPRMRLLREVTAEVLDARHGGRGVLGVCLGHELIAAELGLPLVRKRVPYQGAQVAIDLFGRWETVGFYNSYVASCDDEAATELAAHGVEVSRDAAGEVHALRGPGFASVQFHPESVLSLRGPALVAELLAGVPVETG
>NZ_CP047147.1|WP_106428967.1|1564122_1564248_+|trp-operon-leader-peptide
MGRATHCHASAPGGGGGCATIRPMTAQQTQNWWWTAHPAAR
>NZ_CP047147.1|WP_003947612.1|1562718_1564071_-|3-deoxy-7-phosphoheptulonate-synthase-class-II
MTSTVENSAARVPSWRTLPAAQQPEYPDQEALARVVTELESFPPLVFAGECDQLRARLGAVARGEAFLLQGGDCAESFDGVGADDIRAKVKTLLQMGAVLTYAASVPVVKVGRIAGQYSKPRSKPTETRDGVTLPTYRGDSVNGFDFTEAARVPDPERLKRMYHASASTLNLVRAFTTGGYADLRQVHAWNQDFVKSSPSGQRYEKLAREIDNAMSFMRACGAEPEEFRTVEFYASHEALLLDYETALTRTDSRTGHLYDVSGHMVWIGERTRQMDGAHIEFASKVRNPIGIKLGPTTTPEEALEYIERLDPEREPGRLTFIVRMGADKIRDRLPTLVEKVTASGAQPVWVTDPMHGNTFEAASGHKTRRFDDVLDEVKGFFEVHKELGTHPGGIHVELTGDDVTECVGGGDEIFVDDLHQRYETACDPRLNRSQSLDLAFLVAEMYRGQ
>NZ_CP047147.1|WP_003947621.1|1572990_1573932_-|ROK-family-glucokinase
MGLTIGVDIGGTKIAAGVVDEEGAILNTFTVPTPATAEAIVDAIASAVEGAREGHEIEAVGIGAAGYVDDKRATVLFAPNIDWRHEPLKDKVEQRVGLPVVVENDANAAAWGEYRFGAGKGHDDVICITLGTGLGGGIIIGNKLRRGRFGVAAEFGHIRVVPDGLLCGCGSQGCWEQYASGRALVRYARQRAAATPENAVLLLSLGDGTTEGIQGKHVSEAARQGDPVAVDSFRELARWAGAGLADLASLFDPSAFIVGGGVSDEGELVLDPIRKSFRRWLIGGAWRPHAQVLAAQLGGKAGLVGAADLARQG
>NZ_CP047147.1|WP_159312068.1|1574012_1574501_-|hypothetical-protein
MSDATERPGTDRPGADEDAWGQACAEDFAAEQERRRARYGTPPGSAAEELRKLMEAVTGKLAEGNLLGAAVQGAEEAVRQARAAAEPVIARNPEVFGHLAAAGSELLAAYRSAVEKQESGWTKGTGAATPPPRKPEEPTGEARPGGRPDDEGPGPAEHIDLD
>NZ_CP047147.1|WP_018470628.1|1574577_1575768_-|hypothetical-protein
MRTVLVTGPGGAGRTTLAAATARAAARTGTRVLLLTADPGDRLGTALGTPLGPAPVEAAPGLHALRLDAADRLRADLLALQERAATALDALGATPLAADELTPLPGAEELALLRALRELAALPDGDPARPGLVVVDLPAAPRALALLSLPGELRRYLARLLPAERQAARALRPLLGRLAGLPLPGEGLYAAAARWDTELAAAQAALTRPGTSVTLVAEPGPAGADALREARTALALHALPAGPVLANRVLPAEGAGAWAAPLLAQQAKTLDAWDQDPGGPAVRVPHLGHDPRGPEDLDALGVPAPGPVPAAAGPRVEDRLAEDGVLLWRLELPGATRDQLDLVRRSDELVVTAGPFRRILPLPAALRRCTVAGAALRDGALTVRFAPDPAQWPQGR
>NZ_CP047147.1|WP_003947624.1|1575815_1576262_-|SRPBCC-family-protein
MAEHTSSSITIDAAPAEVMAVIADFARYPEWTGEVKEADVLATDDQGRAEQVRLVLDAGAIKDDHTLAYTWHGPDQVRWTLVKSQMLRELDGSYTLAALGEGRTEVTYQLTVDVKIPMLGMIKRKAEKVIIDRALAGLKKRVESHPDA
>NZ_CP047147.1|WP_008413322.1|1576411_1577182_-|metallophosphoesterase
MAGTRIHVVSDVHGNAKDLARAGEGADALVCLGDLVLFLDYRDHSRGIFPDLFGAEAATRVVELRTARRFEEARAFQRTLWAGIDREQALEAAVRRQYAELFAAFPTPTYATYGNVDVPRLWPEYARPGTTVLDGTRAEIGGRVFGFVGGGLPSPMRTPYEVPEEEYAAKIEALGEVDVLCTHIPPQVPELLYDTVARRFERGSSALLDAIHRTRPRYALFGHVHQPLARRMRIGATECVNVGHFASTGKPWALTW
>NZ_CP047147.1|WP_003947626.1|1577461_1579258_+|long-chain-fatty-acid--CoA-ligase
MREFSLPALYEVPADGNLTDIVRRNAERHPDVAVIARKVDGAWEDLTATAFLAEVRAAAKGLMASGVQPGDRVGLLSRTRYEWTLMDFAIWSAGAVTVPVYETSSPEQIEWILGDSGAVACVVETPAHAASVESVRGALPALKHVWQLDAGGVAELERAGAGLSDEAVDERSALAGADDPATIVYTSGTTGRPKGCVLTHRSFFAECGNVVARLKPLFRTGECSVLLFLPVAHVFGRLVEVAALMAPIRLGLVPDIKHLTDELASFRPTMVLGVPRVFEKVYNSARAKAQADGKGKIFDKAADTAIAYSRALDTPQGPSLGLKLKHKLFAKLVYSKLHTVLGGRGEYAISGGAPLGERLGHFYRGIGFSVLEGYGLTESCAATAFNPWDRQKIGTVGQPLPGSVVRIADDGEVLLHGEHLFDRYWNNEAATREALADGWFHTGDIGTLDEDGYLAITGRKKEIIVTAGGKNVAPAVIEDRIRGHALVAECMVVGDGRPFVGALVTVDEEFLVRWAADHGKPAGSTAASLREDPELLAEIQRAVDDGNAAVSKAESVRKFRVLPSQFTEESGHITPSLKLKRGVVLKDFADEIEAIYTR
>NZ_CP047147.1|WP_030769006.1|1579348_1580491_-|glycosyltransferase-family-4-protein
MDKTLIVTNDFPPRPGGIQAFLHNMALRLDPDRIVVYASTWKRGREGAEATAAFDAEQPFPVVRDRTTMLLPTPAATRRATGLLREHGCTSVWFGAAAPLGLMAPALRRAGARRLVATTHGHEAGWAQLPGARSLLRRIGQSTDTITYLGEYTRSRIARALTPEAAARMAHLPPGVDEKTFHPDSGGDAVRARLGLTDRPVVVCVSRLVPRKGQDTLIKAMPRVLAAQPEAVLLIVGGGPYEKELRALAETTGVARSVHFTGPVPWSELPAHYGAGDVFAMPCRTRRGGLDVEGLGIVYLEASATGLPVVAGDSGGAPDAVLDGETGWVVRGTRPEDVADRLTTLLADPALRAAMGERGRAWVESTWRWDLLADRLRALL
>NZ_CP047147.1|WP_159312069.1|1580609_1581905_+|DUF2029-domain-containing-protein
MTATTDATATRGAAGGDRPPPTAGILAPVAVWAATRAALLLCVLQVWVVPGPDVTVDVSVIYRNWYGVLSTGAFPADDVTWQYPPAAALAILSPALLPFLEYAHAFFVLVLLADAVVLTLLLRASHGPDRSRRGVWVWVAGVVLLGPTAYARYDLMVAAVAVAALVAGVGRPRLMGALVAFGALLKVWPALLLIGVARGAVRRVWVSAAVTGSVVLAAFAVAMPNALGFLTAQRDRGTEVESLGALVFHVARYFGWQGEVQLHYGSLEFLGPGVAGVSLAAQLLSVVALGWLVYWRLRARVFAAGTTADAAFTAVLLFTTTSRVISPQYLLWLVALAAVCLLFAGSGMTRPAVLVVAASAVTVLEFPVFFGDVVGSTPLGVGLMLVRNGLLVAACLLAGRALWRRTVPGAAGATPDGLSPAPPGGTPARQP
>NZ_CP047147.1|WP_159312070.1|1581861_1583046_-|hypothetical-protein
MTEAQGLPGRRRAARLGLAALLAAGCAPASGPPPPGQAAAAALLGRRAAALRERDPAAWTATSTGGTGQDSLWARLAGVPLAGWAYRVTGVRAGDATATVEATLRYRLRGEDPAPATARRLLGLVRHEGRWRVRSEEAAPGAAQLLWDQGPVRARQGSWGLVLGTGSAGELAAFARLAERAVPVADEAWGGDWPRRVVVLVPGSLAGTAALLGGEPDAYRGVAAVTTGSPEPGTPADRIVVNPEAYRELDARGKQFVLTHETVHVATRSVTGPATPLWLSEGFADLAAHRAAPRPLAAAAPALTAAVARDEVPRALPDDAAFAFDGDSGALDRAYEGGWLACRLLADRWGEERLRAFYRAAGTRGGQAAFREVLGTTRAEFTAAWRAYLREELG
>NZ_CP047147.1|WP_015508015.1|1583085_1584060_-|C40-family-peptidase
MTAATALSAAAATAAATLGGAAPAEAKPEPAATRASVERLLTEAERATEAFNKADERTGALRAELRRTQDRVARGQDRVNTMRGALGALAGAQYRSGGVDPALELIFSADPEQYLEKAATLDRISLRRAGELNRLTQAQRLLTQERAEAAATLAELTRSRAATARHKRTVEAKLARARALLAALPDGERDAHDRRASRSDRPDLGGIALSGRAGTAVAAVQRALGKPYVWGANGPGGFDCSGLMQWAYAQAGVGLPRTSQAQRNAGQHVPLSQARPGDLVTYRADASHVGMYVGNGQVIHAPYPGASVRYDPVGMMPIASVTRV

Crispr_ID: NZ_CP047147_5

• CRISPR_ID: NZ_CP047147_5
• CRISPR_location: 1661363-1661449
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP047147_5

Consensus_repeat	Method
TGGCCTCAAACGCCGGCCGGGCT	CRISPRCasFinder

spacers of NZ_CP047147_5

>5.1|1661386|41|NZ_CP047147|CRISPRCasFinder
GTTGTGTGCCGGGCTCCGTCCCGACCGTGCCGGTCAAAGAC

CRISPR arrays and Neighbor proteins around NZ_CP047147_5

CRISPR arrays

The CRISPR arrays of NZ_CP047147_5

>merge|NZ_CP047147|5|1661363-1661449|CRISPRCasFinder
TGGCCTCAAACGCCGGCCGGGCTGTTGTGTGCCGGGCTCCGTCCCGACCGTGCCGGTCAAAGACTGGCCTCAAACGCCGGCCGGGCT

>NZ_CP047147|5|4|1661363-1661449|CRISPRCasFinder
TGGCCTCAAACGCCGGCCGGGCT	GTTGTGTGCCGGGCTCCGTCCCGACCGTGCCGGTCAAAGAC
TGGCCTCAAACGCCGGCCGGGCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_159312084.1|1670533_1671871_-|precorrin-3B-synthase	unknown	unknown	gnl|CDD|274131
NZ_CP047147.1|WP_095712092.1|1669914_1670541_-|precorrin-8X-methylmutase	unknown	unknown	gnl|CDD|181352
NZ_CP047147.1|WP_159312080.1|1654636_1655527_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_003947697.1|1657598_1658336_+|HAD-family-phosphatase	unknown	unknown	gnl|CDD|223710
NZ_CP047147.1|WP_010637417.1|1662005_1663004_-|polyphosphate-kinase-2	unknown	unknown	gnl|CDD|213852
NZ_CP047147.1|WP_003947691.1|1651003_1651702_+|DUF4191-domain-containing-protein	unknown	unknown	gnl|CDD|379389
NZ_CP047147.1|WP_015508002.1|1658350_1659013_-|dihydroxyacetone-kinase-subunit-L	unknown	unknown	gnl|CDD|237723
NZ_CP047147.1|WP_159312085.1|1672419_1676028_+|cobaltochelatase-subunit-CobN	unknown	unknown	gnl|CDD|235663
NZ_CP047147.1|WP_121841908.1|1668352_1669918_-|precorrin-2-C(20)-methyltransferase	unknown	unknown	gnl|CDD|381173
NZ_CP047147.1|WP_037784883.1|1656398_1657061_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|366102
NZ_CP047147.1|WP_003947698.1|1659071_1660064_-|dihydroxyacetone-kinase-subunit-DhaK	unknown	unknown	gnl|CDD|376910
NZ_CP047147.1|WP_030769105.1|1666724_1667477_+|precorrin-4-C(11)-methyltransferase	unknown	unknown	gnl|CDD|225430
NZ_CP047147.1|WP_121841907.1|1667460_1668231_+|cobalt-precorrin-6A-reductase	unknown	unknown	gnl|CDD|236144
NZ_CP047147.1|WP_146583262.1|1663234_1664446_+|cardiolipin-synthase-B	unknown	unknown	gnl|CDD|234967
NZ_CP047147.1|WP_003947693.1|1652507_1653917_+|type-I-glutamate--ammonia-ligase	unknown	unknown	gnl|CDD|273198
NZ_CP047147.1|WP_159312082.1|1664581_1665277_+|hypothetical-protein	unknown	unknown	gnl|CDD|311556
NZ_CP047147.1|WP_159312083.1|1665421_1666660_+|precorrin-6y-C5,15-methyltransferase-(decarboxylating)-subunit-CbiE	unknown	unknown	gnl|CDD|225151
NZ_CP047147.1|WP_003947690.1|1650666_1650900_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159312081.1|1660414_1661272_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_003947692.1|1651797_1652265_-|RDD-family-protein	unknown	unknown	gnl|CDD|377640

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_159312084.1|1670533_1671871_-|precorrin-3B-synthase	gnl|CDD|274131	TIGR02435, Precorrin-3B_synthase, precorrin-3B synthase. An iron-sulfur protein. An oxygen atom from dioxygen is incorporated into the macrocycle at C-20. In the aerobic cobalamin biosythesis pathway, four enzymes are involved in the conversion of precorrin-3A to precorrin-6A. The first of the four steps is carried out by EC 1.14.13.83, precorrin-3B synthase (CobG), yielding precorrin-3B as the product. This is followed by three methylation reactions, which introduce a methyl group at C-17 (CobJ; EC 2.1.1.131), C-11 (CobM; EC 2.1.1.133) and C-1 (CobF; EC 2.1.1.152) of the macrocycle, giving rise to precorrin-4, precorrin-5 and precorrin-6A, respectively. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin].	4.46175e-62
NZ_CP047147.1|WP_095712092.1|1669914_1670541_-|precorrin-8X-methylmutase	gnl|CDD|181352	PRK08285, cobH, precorrin-8X methylmutase; Reviewed.	3.12102e-129
NZ_CP047147.1|WP_030769105.1|1666724_1667477_+|precorrin-4-C(11)-methyltransferase	gnl|CDD|225430	COG2875, CobM, Precorrin-4 methylase [Coenzyme metabolism].	4.08301e-125
NZ_CP047147.1|WP_003947697.1|1657598_1658336_+|HAD-family-phosphatase	gnl|CDD|223710	COG0637, COG0637, Predicted phosphatase/phosphohexomutase [General function prediction only].	2.01391e-39
NZ_CP047147.1|WP_010637417.1|1662005_1663004_-|polyphosphate-kinase-2	gnl|CDD|213852	TIGR03707, PPK2_P_aer, polyphosphate kinase 2, PA0141 family. Members of this protein family are designated polyphosphate kinase 2 (PPK2) after the characterized protein in Pseudomonas aeruginosa. This family comprises one of three well-separated clades in the larger family described by pfam03976. PA0141 from this family has been shown capable of operating in reverse, with GDP preferred (over ADP) as a substrate, producing GTP (or ATP) by transfer of a phosphate residue from polyphosphate. Most species with a member of this family also encode a polyphosphate kinase 1 (PPK1). [Central intermediary metabolism, Phosphorus compounds].	1.49165e-146
NZ_CP047147.1|WP_003947691.1|1651003_1651702_+|DUF4191-domain-containing-protein	gnl|CDD|379389	pfam13829, DUF4191, Domain of unknown function (DUF4191).	3.92239e-108
NZ_CP047147.1|WP_015508002.1|1658350_1659013_-|dihydroxyacetone-kinase-subunit-L	gnl|CDD|237723	PRK14479, PRK14479, dihydroxyacetone kinase; Provisional.	2.04606e-54
NZ_CP047147.1|WP_159312085.1|1672419_1676028_+|cobaltochelatase-subunit-CobN	gnl|CDD|235663	PRK05989, cobN, cobaltochelatase subunit CobN; Reviewed.	0
NZ_CP047147.1|WP_121841908.1|1668352_1669918_-|precorrin-2-C(20)-methyltransferase	gnl|CDD|381173	cd11646, Precorrin_3B_C17_MT, Precorrin-3B C(17)-methyltransferase (also named CobJ or CbiH). Precorrin-3B C(17)-methyltransferase participates in the pathway toward the biosynthesis of cobalamin (vitamin B12). There are two distinct cobalamin biosynthetic pathways. The aerobic pathway requires oxygen, and cobalt is inserted late in the pathway; the anaerobic pathway does not require oxygen, and cobalt insertion is the first committed step towards cobalamin synthesis. This model includes CobJ of the aerobic pathway and CbiH of the anaerobic pathway, both as stand-alone enzymes and when CobJ or CbiH form part of bifunctional enzymes, such as in Mycobacterium tuberculosis CobIJ where CobJ fuses with a precorrin-2 C(20)-methyltransferase domain, or Bacillus megaterium CbiH60, where CbiH is fused to a nitrite and sulfite reductase-like domain. In the aerobic pathway, once CobG has generated precorrin-3b, CobJ catalyzes the methylation of precorrin-3b at C-17 to form precorrin-4 (the extruded methylated C-20 fragment is left attached as an acyl group at C-1). In the corresponding anaerobic pathway, CbiH carries out this ring contraction, using cobalt-precorrin-3b as a substrate to generate a tetramethylated delta-lactone.	9.99972e-116
NZ_CP047147.1|WP_037784883.1|1656398_1657061_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	4.88065e-11
NZ_CP047147.1|WP_003947698.1|1659071_1660064_-|dihydroxyacetone-kinase-subunit-DhaK	gnl|CDD|376910	pfam02733, Dak1, Dak1 domain. This is the kinase domain of the dihydroxyacetone kinase family EC:2.7.1.29.	7.88315e-146
NZ_CP047147.1|WP_121841907.1|1667460_1668231_+|cobalt-precorrin-6A-reductase	gnl|CDD|236144	PRK08057, PRK08057, cobalt-precorrin-6x reductase; Reviewed.	8.48163e-104
NZ_CP047147.1|WP_146583262.1|1663234_1664446_+|cardiolipin-synthase-B	gnl|CDD|234967	PRK01642, cls, cardiolipin synthetase; Reviewed.	3.51543e-91
NZ_CP047147.1|WP_003947693.1|1652507_1653917_+|type-I-glutamate--ammonia-ligase	gnl|CDD|273198	TIGR00653, Glutamine_synthetase, glutamine synthetase, type I. Alternate name: glutamate--ammonia ligase. This model represents the dodecameric form, which can be subdivided into 1-alpha and 1-beta forms. The phylogeny of the 1-alpha and 1-beta forms appears polyphyletic. E. coli, Synechocystis PCC6803, Aquifex aeolicus, and the crenarcheon Sulfolobus acidocaldarius have form 1-beta, while Bacillus subtilis, Thermotoga maritima, and various euryarchaea has form 1-alpha. The 1-beta dodecamer from the crenarcheon Sulfolobus acidocaldarius differs from that in E. coli in that it is not regulated by adenylylation. [Amino acid biosynthesis, Glutamate family].	0
NZ_CP047147.1|WP_159312082.1|1664581_1665277_+|hypothetical-protein	gnl|CDD|311556	pfam07681, DoxX, DoxX. These proteins appear to have some sequence similarity with pfam04173 but their function is unknown.	0.00732449
NZ_CP047147.1|WP_159312083.1|1665421_1666660_+|precorrin-6y-C5,15-methyltransferase-(decarboxylating)-subunit-CbiE	gnl|CDD|225151	COG2242, CobL, Precorrin-6B methylase 2 [Coenzyme metabolism].	8.98274e-71
NZ_CP047147.1|WP_003947692.1|1651797_1652265_-|RDD-family-protein	gnl|CDD|377640	pfam06271, RDD, RDD family. This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N-terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown. However this region may be involved in transport of an as yet unknown set of ligands (Bateman A pers. obs.).	2.42003e-12

Protein sequences

>NZ_CP047147.1|WP_159312081.1|1660414_1661272_+|hypothetical-protein
MPKQSPDGNQEHEDGRAGRAPHAREVERPSRHEITEADRKGGPGHTVLLALALAIPAVKVAYTLGGGGAATDALMGMGPGNWWDVLLGMVLTTPLLACVLGVVASRVVFALFAARGAVPRGDDPAARLRRAGLTVLNPVATGVVVACFIGPWWGLGTAVAAYLLRRGVVIEYRTGRRGRRHHDPHFAPPGWQRRLATGEQVVALTLSVVVLPLLGVVSALDGQAWTSVVRCEVSDGARTRVARLIELQRQGNGVVGWNLDQGEVSNGVGCTGVESRTVRAPWWRA
>NZ_CP047147.1|WP_003947698.1|1659071_1660064_-|dihydroxyacetone-kinase-subunit-DhaK
MASYFENSSDALVPDALKGFARAHADLVTLDPEHGFLLSRTAAPSRRVALLSGGGAGHEPLHAGYVGRGMLDAACPGRVFASPHNRQVYAGSLAAARAEGVLHIVKNYTGDRINFGIAAERLAHRGVPCARVLIDDDLASDSADIASGRRGTGGTVLIEKILGAAADTGLGLAELQELGTRLAARCRTLAVASAAHTAPTTGEPAFPLAAGELEYGVGIHGERAQQTVPREPLNGLVERMTTALLDALAPEGPVIALVNGLGAVTPLELYAVHGELATLLDARGTDLARALVGDYITALDMRGFSVTLLAADEEILRLYDAPVHTAALRW
>NZ_CP047147.1|WP_015508002.1|1658350_1659013_-|dihydroxyacetone-kinase-subunit-L
MTTSTSHDATATDGWMRRFAESAHATETRLTSLDQQVGDGDFGTNLTAGADAALRRLDQLPGGDTDPAAPLEAAATAFLDEVGGTSGPLFGLLLQSLAAAVAGSGPTTAAYAEGVTDGLAAIRRVGDAAPGDKTLVDALTPAAEALRATPAGTPPDQALAAAADAAWEGVRSTARLRARMGRSSYLGERAEGIPDPGAVGVGLLFASAQGVVTDLDTHLG
>NZ_CP047147.1|WP_003947697.1|1657598_1658336_+|HAD-family-phosphatase
MTTKAHPLLSWSPEAVVFDCDGTLMDTERHWQDARSQVFRQFGLRPLPGFAERAKGVHYTDCGRLMAEESDKPHLAGELTESLLTHFMELVADDPVTMPGAAEFVRRLSGRLPLAVASNCPLEVVEMSLERAGLLHHFRHVVVPDEPSTGAAPGSATVRPKPWPDVYARAAWLCGADPDSTLAVEDSLTGIESARRAGLRVLGVGPRPGEEDASRADLWVTTLHSPVLLAWVRAHVPQQGGSAEG
>NZ_CP047147.1|WP_037784883.1|1656398_1657061_-|TetR/AcrR-family-transcriptional-regulator
MQERARATRRSLLEAAALLFAEQGYAGTSVNDISARSGRTSGAVYFHYASKEGLALAVVQHRFATWPGLAARYTDRAEPPLEKLVALSFDIAHALAEDPLARAGARLWAERDTIDAPLPDPFALWTTATTRLLAQARTAGHLTPHIRPAPTARSLVRAFFGLCTLTEALEGPTAVTARLTDWWLLTLGSLQQRPDAAGVLGRVRARGGRAEARMGAACGE
>NZ_CP047147.1|WP_159312080.1|1654636_1655527_+|hypothetical-protein
MPESSRKSAARSRVLYTGEKLAAAQAGIPRDHSIGLDACRPEQSQFRALLALGYLNHGVDYDGPAGWHLSALSSYTVTVSPRFERTVIITKVPHNVAQRMLPGPVGGSGLPGLRLEQCRGYGSYTLRHMPTGAELVITDNPFGRPVGTPNAPYFDCLTSDAPLSVAEAEQLGRVPDMSVDARRLLAGVFCRITTKDPCGAWAIGNWFYDPLERPGWLDSLHLPGCRSLRGFGDNWELEWEADPYPEDLTSALTGSVIGIPGASAASTFGHLAVTLGSATLHLRSARSCAAKRQSRL
>NZ_CP047147.1|WP_003947693.1|1652507_1653917_+|type-I-glutamate--ammonia-ligase
MFQNADDAKKFIADEDVKFVDVRFCDLPGVMQHFTIPAKAFDADEELAFDGSSIRGFQAIHESDMSLRPDLSTARVDPFRRDKTLNINFFIHDPITGEQYSRDPRNIAKKAEAYLASTGIADTAYFGPEAEFYVFDSVRFETSANQGFYHIDSEAGAWNTGSEVENRGYKVRYKGGYFPAPPVDHFADLRAEISLELEQAGLEVERQHHEVGTAGQAEINYKFNTLLAAADDLMLFKYIVKNVAWRNGKTATFMPKPIFGDNGSGMHVHQSLWSGGTPLFYDEQGYAGLSDTARYYIGGILKHAPSLLAFTNPTVNSYHRLVPGFEAPVNLVYSQRNRSAAMRIPITGSNPKAKRVEFRAPDPSSNPYLAFSALLLAGLDGVKNKIEPAEPIDKDLYELAPEEHAGVPQVPTSLPAVLDALEADNEYLQAGGVFTPDLIDTWIDYKRTQEIAPIQLRPHPHEFELYFDL
>NZ_CP047147.1|WP_003947692.1|1651797_1652265_-|RDD-family-protein
MDNRQAIGSWLSGPRAAAEEMGADFGYRGERLGLPEHGPGSVAPVGRRFGALAIDWALCMLIAYGLFSGGDAQSTGNWALGILLVMNILTVGTVGCTPGKLLLRLRVVSEQGGRLGPGWTVVRSALLCLGVPALIWDRDSRGLHDRLGRAVQIRV
>NZ_CP047147.1|WP_003947691.1|1651003_1651702_+|DUF4191-domain-containing-protein
MASKDNAASSANPGRIKQIAQTYKMAKRVDPKIGWVIAAVGIVTFGVFLAIGFLVGHPVYLGILGFVLAFLAMAIIFGRRAEKAAFSQMEGQPGAAAAVLDNIGRGWTTTPAVAVNRSQDVVHRAVGKAGIVLVAEGNPNRVKGLLASEKKKMARIVVDVPVHDIVVGTGEGQTPLKKVRTTMLKYPRVLTGPQVTATNDRLRALGDLMSNMPVPKGPMPKGARMPRGPKMR
>NZ_CP047147.1|WP_003947690.1|1650666_1650900_+|hypothetical-protein
MQAAPVTPLRTSTTRPAAWPSVTGALRAVESVLMRSGQRTARRNAWASVLEDRRRAQDRVETQAVLEAAATPGSRTS
>NZ_CP047147.1|WP_010637417.1|1662005_1663004_-|polyphosphate-kinase-2
MESAAEQHGADRTEPGIHDADDTLLEGLSVDASRPEQPVLREADGTPVRTWRENYPYDRKLRRREYERRKRVLQIELLKLQSWVKETGARIVIVCEGRDAAGKGGTIKRFTERLNPRGARVVALDKPTEKEAGQWYFQRYIAHLPSPGEIVFFDRSWYNRAGVERVMGFCTEEQYEQFLVQAPLFEKMITSDGILLVKFWFSVSRSEQRTRFAIRQVDPVRQWKLSPTDLASLDLWDAYTRAKIEMFRATDTVWAPWTVVKTNDKRRGRLEAMRSLLLRVEYAAKDGGALGEGDPLIVGPADTLLEPGEEPTSLSPTPLADHDEGRGSHPDS
>NZ_CP047147.1|WP_146583262.1|1663234_1664446_+|cardiolipin-synthase-B
MTMTEVAEDDPGAGGGEALAVRGRRLRRRLERLIGVAATEGNELTALRNGDEIFTAMLSAIREAEHTVDLMTFVYWKGEIARDFAAALCERAKAGVRVRLLLDGFGSRLIERHLLEEMDEAGVHVSWFRKPFLLSPFKQNHRCHRKVLVVDEKVAFTGGVGIAEEWCGDARNENEWRDTHVRLRGPAVDGVAAAFAQNWAECCDDLFDERDRFTAQPPSGGAVVQVVRGSASFGWQDMQTLLRVVLQSAEERVRIATAYFAPDAYFIDLLCATAARGVEVEILLPGPHTDKRVCQLAGQWHYDQLLGCGVRIHQYQPTMMHAKVITVDRVAALTGSTNINRRSLDHDEEVMLAVIDEEFTAVLDRHFDEDTEVSVEMQAGRYRRRSWLQRGREAMVVPIRRFL
>NZ_CP047147.1|WP_159312082.1|1664581_1665277_+|hypothetical-protein
MSGCGKVKAWQVPLRLVTGAFILHSGMEKWDGPDEQAQGVHGMARQTFPFLENIDAPRFLKLLAAGEIALGAALLTPMVPTRFAGAALTGFAGSLMAVYAQTPGLRKEGSVWPTPDGIGVSKDSWLLAIGLALTLSPHQKHHKHVKHIKHAQHVKHVKHAKGHGGCHKHHCHHEQGGHPGHHGHLKQAKLVAREAKEAKRLAKGVSPDGHSHHHAHRHGPGHARKGCPAHH
>NZ_CP047147.1|WP_159312083.1|1665421_1666660_+|precorrin-6y-C5,15-methyltransferase-(decarboxylating)-subunit-CbiE
MTPISEQPAVTVVGIGADGWAGLGPAEREALAAAEVVVGGPRQLDLLPPECAGERVAWPSPLRPAVPKLLAEHAGRRLAVLASGDPMFYGIGRALAEEAGPAALHVLPHPSSVSYACARMGWAMQDVEVVSAVGRDAAALAGALHDGRRVLVLAPDAATPSRIAELLRERGYGPSRMTVLEQLGGPAEHRVDGVAGTWSAPAGDPLNVVAVECVRAAGTPRLPVVPGLPDDAYEHDGQLTKKYVRAATLAALAPAPGELLWDVGGGSGSIAVEWLRAHRACRAVSVERDPLRAGRITRNARALGVPRLKVVTGAAPGALAGLPVPDAVFIGGGLTGAGLLETCWAALPAGGRLVANTVTLESEALLTEWYRRHGGELTRLAVAQAVPVGSFTGWRQAMPVTQWSVTKPAEHM
>NZ_CP047147.1|WP_030769105.1|1666724_1667477_+|precorrin-4-C(11)-methyltransferase
MTVYFIGAGPGAADLITLRGARTLAACQVCLYAGSLVPTELLAECPPDARLVDTAQLDLDRITAELIRAHEEGHDVARLHSGDTSVFSAVAEQMRRLDAAGVPYEVVPGVPAFAAAAAALKRELTVPTVGQTVILTRVAQRATPMPEGEDLATLGRSGALLVLHLATGYADRVVAELEPHYGADCPAAVVAFASRPEELVLRGTLADIAGQVREAGIRRTAVILVGRTLGAEQFRDSHLYSPDRDRDHVC
>NZ_CP047147.1|WP_121841907.1|1667460_1668231_+|cobalt-precorrin-6A-reductase
MTTSADSAPPLVLVLGGTSESRRLAALLTRGAAGPLRVVSSLAGRVARPVLPEGEVRIGGFGGVAGLTAYLREERVAAVVDATHPFAGVMSFHAAEAAAGAGVPLLALRRPSWRQGPGDRWYPVASLEEAAALLPSLGRRVFLTTGRSGLGAFADAAPGLWFLLRSVDPPVGPGPEECEVLLDRGPFTLEGEREVLRTYGVEVLVTKDSGGEATAPKLTAAREAEIPVVVVRRPPVPEGVPVVGTPEEAVAWLGGG
>NZ_CP047147.1|WP_121841908.1|1668352_1669918_-|precorrin-2-C(20)-methyltransferase
MSTPAPGRLYGVGLGPGDPNLMTLRAVQVIADADVVAYHSARHGRSIARSIAAAHLRPDHIEEALVYPVTTGTTDHPGGYQGAMDDFYAACAERLAVHLDAGRTVAVISEGDPLFYGSYMHMHKRLAHRYPTEVIPGVTSVSAASARLGAPLVEGEEVLTILPGTLPEEELTARLAATDSAVVMKLGRTFPAVRGALEASGRLAEARYVERATMEGERTGHLADTDPESVPYFAVAVVPSRVAALPVDAPATGQAAVPAEEEAAAVPAGEVVVVGTGPAGPLWLTPETRGALAAAQDLVGYTTYLDRVPHRPGQIRHGSDNKVEAERAEFALDLARRGRRVAVVSGGDPGVFAMATAVLEAAAEGPYRDVPVRVLPGVTAANAAAARAGAPLGHDYAVISLSDRLKPWEVIAERLAAAARADLALALYNPGSRSRTWQVGKARDLLLEHRSPDTPVVLARDVGGSGERVRTVRLADLDPAEVDMRTLLIIGSSQTRAVRRTPDAPETVWTPRRYPEPTTGA
>NZ_CP047147.1|WP_095712092.1|1669914_1670541_-|precorrin-8X-methylmutase
MFEYEKDGAAIYRESFATIRAEADLTGLPPDVAQVAVRMIHACGMTDLPRDLGHTPQVVARARRALRAGAPILCDANMVASGVTRRRLPADNEVICTLADPSVPELAARLGTTRSAAALELWRDRLDGAVVAVGNAPTALFRLLEMIEEGAPRPAAVIGVPVGFVGAAESKDALAAHPSGLDHLIVRGRRGGSAMAAAALNAIASETE
>NZ_CP047147.1|WP_159312084.1|1670533_1671871_-|precorrin-3B-synthase
MPTPARGDACPGALRLHEAADGHLARVRIPGGLLRAPQAMALARAAEDLGDAHLDLTSRGNVQLRALPADAGRELAARLAEADLLPSPAHERIRNLVASPLSGLDDEGHADVTPLVPAVDAALLADPATTALSGRFLFALDDGRGDTAALDADVTMLATPDGDLALTLPGVPGSLRLPPDQVPAAAHAAALLFLAAARASGTRAWRVAELPPGRALSTATLTELAARVPGSRTAPAPEPLAPYGGPRPGPTPPRAGRSALHALAPLGRLTAYQWRELAELAARHGAGTLRATPWRGIVVPGLTPDRAAEAAAGLARAGLVTGEGSPWEGVGACTGRPGCVKSLADVRADARAALDAAPGGLPVYWSGCERRCGHPRGTAWVDAVATGTGYDLAHRPADPAAEPRPAGRDVPAHRLPEALAAARRTPSTPRPTRHGAVRKEREQSV
>NZ_CP047147.1|WP_159312085.1|1672419_1676028_+|cobaltochelatase-subunit-CobN
MILLLSTSDTDLLSARSAGGPVPYRFANPSRLPLDDLPELLDGADLVVVRLLGGVRAWQEGIDALLAQDRPVVVLTGEQAPDAQLMEASTVPIGVAAEAHAYLAHGGPANLEQLARFLSDTVLLTGHGFEAPAPAPSWGPLERTPAPEASGPLIAVLYYRAHHMSDNTGFVDTLCGAIEEAGGRALPLYVASLRSPEPELLAELGRADALVTTVLAAGGTKPAGASAGGDDESWDAGALAALDVPILQALCLTSSRADWEENDEGLSPLDAASQIAVPEFDGRLITVPFSFKELDADGLPVYVADTERAARVAGTAVRHARLRHLPNAEKRLALVLSAYPTKHSRIGNAVGLDTPASAVALLRRLIAEGYDFGDEAIPGLESGDGDELIYALIEAGGHDQDWLTEEQLARNPVRIPAADYRRWYGTLPAELREQVEEHWGPPPGEMFVDRSRNPEGDIVLAALRFGRLLILIQPPRGFGENPIAIYHDPDLPPSHHYLAAYRWIQARAEDGGFGADAMVHLGKHGNLEWLPGKNAGLSAACGPDAALGDLPLVYPFLVNDPGEGTQAKRRVHATLVDHLVPPMARAESYGDIARLEQLLDEYAAISSMDPAKLPAIRAQIWTLIQAAKLDHDLGLEARPDDDGFDDFLLHVDGWLCEVKDAQIRDGLHVLGSAPADEARVSLVLAILRARQIWGGTTALPGLREALGLDESAATRTTADEAEERARALVQAMDDAGWDPQAAARVAEGHGQAVADILAFAAREVVPRLAATTDELDHAVHALNGGFVPAGPSGSPLRGLVNVLPTGRNFYSVDPKAVPSRLAWETGQALADSLLERYRADHGDWPVSVGLSLWGTSAMRTSGDDVAEALALLGVRPVWDDASRRVTGLEAVPLEELGRPRVDVTLRISGFFRDAFPHTIGLLDDAVRLVAGLDEPDKDNHVAAHARADLAEHGDERRATTRIFGSRPGTYGAGLLQLIDSRDWRTDADLAEVYTVWGGYAYGRELEGREARAEMESAYRRIAVAAKNTDTREHDIADSDDYFQYHGGMVAAVRALKGTAPEAYIGDSTRPETVRTRTLVEETSRVFRARVVNPKWIEAMRRHGYKGAFELAATVDYLFGYDATTGVVADWMYDKLTETYVLDPENRAFLQEANPWALHGIAERLLEAESRGMWAEPDPEILAALRQAYLETEGDLESGRDEE

Crispr_ID: NZ_CP047147_6

• CRISPR_ID: NZ_CP047147_6
• CRISPR_location: 1718256-1718416
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP047147_6

Consensus_repeat	Method
CCAATCCAAGCCCGGCCGGCGCTTGAGGCCA	CRISPRCasFinder

spacers of NZ_CP047147_6

>6.1|1718287|43|NZ_CP047147|CRISPRCasFinder
TCTGTGACCCGCAGCGGACAACCACCCGCAGCCACATCCCAGC
>6.2|1718361|25|NZ_CP047147|CRISPRCasFinder
ATCCAAGCCCGGCCGGCGCTTGAGG

CRISPR arrays and Neighbor proteins around NZ_CP047147_6

CRISPR arrays

The CRISPR arrays of NZ_CP047147_6

>merge|NZ_CP047147|6|1718256-1718416|CRISPRCasFinder
CGAATCTCAGTCCGGCCGGCGCTTGAGGCCATCTGTGACCCGCAGCGGACAACCACCCGCAGCCACATCCCAGCCCAATCCAAGCCCGGCCGGCGCTTGAGGCCAATCCAAGCCCGGCCGGCGCTTGAGGCCAATCCAAGCCCGGCCGGCGCTTGAGGCCA

>NZ_CP047147|6|5|1718256-1718416|CRISPRCasFinder
CGAATCTCAGTCCGGCCGGCGCTTGAGGCCA	TCTGTGACCCGCAGCGGACAACCACCCGCAGCCACATCCCAGC
CCAATCCAAGCCCGGCCGGCGCTTGAGGCCA	ATCCAAGCCCGGCCGGCGCTTGAGG
CCAATCCAAGCCCGGCCGGCGCTTGAGGCCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_159313867.1|1712984_1713905_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159312097.1|1717610_1718195_+|pyridoxamine-5'-phosphate-oxidase-family-protein	unknown	unknown	gnl|CDD|334450
NZ_CP047147.1|WP_159312104.1|1728957_1729695_+|DUF2637-domain-containing-protein	unknown	unknown	gnl|CDD|378511
NZ_CP047147.1|WP_159312103.1|1727435_1728776_+|plasmid-transfer-protein	unknown	unknown	gnl|CDD|279863
NZ_CP047147.1|WP_159312100.1|1723961_1725008_+|DUF262-domain-containing-protein	unknown	unknown	gnl|CDD|377008
NZ_CP047147.1|WP_018470689.1|1712345_1712960_+|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|367243
NZ_CP047147.1|WP_159312094.1|1706334_1707408_+|substrate-binding-domain-containing-protein	unknown	unknown	gnl|CDD|224525
NZ_CP047147.1|WP_059212806.1|1720236_1720860_+|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|188483
NZ_CP047147.1|WP_008413651.1|1727097_1727433_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_093847066.1|1707536_1708505_+|phosphatase-PAP2-family-protein	unknown	unknown	gnl|CDD|379588
NZ_CP047147.1|WP_159312099.1|1721344_1722598_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|197775
NZ_CP047147.1|WP_159312096.1|1710675_1712163_-|amino-acid-permease	unknown	unknown	gnl|CDD|223605
NZ_CP047147.1|WP_159312098.1|1718509_1720117_-|MFS-transporter	unknown	unknown	gnl|CDD|129794
NZ_CP047147.1|WP_159312101.1|1725022_1725691_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_010637478.1|1714324_1717330_-|bifunctional-[glutamine-synthetase]-adenylyltransferase/[glutamine-synthetase]-adenylyl-L-tyrosine-phosphorylase	unknown	unknown	gnl|CDD|237613
NZ_CP047147.1|WP_003947735.1|1708630_1709044_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_018470694.1|1720958_1721330_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_008409231.1|1704722_1706006_-|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|270454
NZ_CP047147.1|WP_159312095.1|1709063_1710644_-|amidohydrolase-family-protein	unknown	unknown	gnl|CDD|238625
NZ_CP047147.1|WP_159312102.1|1726147_1726906_-|UTRA-domain-containing-protein	unknown	unknown	gnl|CDD|225099

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_159312097.1|1717610_1718195_+|pyridoxamine-5'-phosphate-oxidase-family-protein	gnl|CDD|334450	pfam01243, Putative_PNPOx, Pyridoxamine 5'-phosphate oxidase. Family of domains with putative PNPOx function. Family members were predicted to encode pyridoxamine 5'-phosphate oxidase, based on sequence similarity. However, there is no experimental data to validate the predicted activity and purified proteins, such as yeast YLR456W and its paralogs, do not possess this activity, nor do they bind to flavin mononucleotide (FMN). To date, the only time functional oxidase activity has been experimentally demonstrated is when the sequences contain both pfam01243 and pfam10590. Moreover, some of the family members that contain both domains have been shown to be involved in phenazine biosynthesis. While some molecular function has been experimentally validated for the proteins containing both domains, the role performed by each domain on its own is unknown.	1.18138e-13
NZ_CP047147.1|WP_159312104.1|1728957_1729695_+|DUF2637-domain-containing-protein	gnl|CDD|378511	pfam10935, DUF2637, Protein of unknown function (DUF2637). This family of proteins has no known function.	1.75574e-11
NZ_CP047147.1|WP_159312103.1|1727435_1728776_+|plasmid-transfer-protein	gnl|CDD|279863	pfam01580, FtsK_SpoIIIE, FtsK/SpoIIIE family. FtsK has extensive sequence similarity to wide variety of proteins from prokaryotes and plasmids, termed the FtsK/SpoIIIE family. This domain contains a putative ATP binding P-loop motif. It is found in the FtsK cell division protein from E. coli and the stage III sporulation protein E SpoIIIE which has roles in regulation of prespore specific gene expression in B. subtilis. A mutation in FtsK causes a temperature sensitive block in cell division and it is involved in peptidoglycan synthesis or modification. The SpoIIIE protein is implicated in intercellular chromosomal DNA transfer.	2.02406e-28
NZ_CP047147.1|WP_159312100.1|1723961_1725008_+|DUF262-domain-containing-protein	gnl|CDD|377008	pfam03235, DUF262, Protein of unknown function DUF262.	1.49041e-22
NZ_CP047147.1|WP_018470689.1|1712345_1712960_+|TetR-family-transcriptional-regulator	gnl|CDD|367243	pfam02909, TetR_C, Tetracyclin repressor, C-terminal all-alpha domain.	4.08823e-09
NZ_CP047147.1|WP_159312094.1|1706334_1707408_+|substrate-binding-domain-containing-protein	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	1.05717e-94
NZ_CP047147.1|WP_059212806.1|1720236_1720860_+|TetR-family-transcriptional-regulator	gnl|CDD|188483	TIGR03968, transcriptional_regulator_TetR_family, mycofactocin system transcriptional regulator. Members of this family are TetR family putative transcriptional regulators that occur in genome contexts near proteins of the mycofactocin system. These include the precursor peptide (TIGR03969), a radical SAM peptide maturase (TIGR03962), and a putative carrier protein (TIGR03967). [Regulatory functions, DNA interactions].	1.71085e-11
NZ_CP047147.1|WP_093847066.1|1707536_1708505_+|phosphatase-PAP2-family-protein	gnl|CDD|379588	pfam14378, PAP2_3, PAP2 superfamily.	1.39108e-51
NZ_CP047147.1|WP_159312099.1|1721344_1722598_-|helix-turn-helix-domain-containing-protein	gnl|CDD|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	6.54015e-11
NZ_CP047147.1|WP_159312096.1|1710675_1712163_-|amino-acid-permease	gnl|CDD|223605	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism].	1.93223e-34
NZ_CP047147.1|WP_159312098.1|1718509_1720117_-|MFS-transporter	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	6.77332e-58
NZ_CP047147.1|WP_010637478.1|1714324_1717330_-|bifunctional-[glutamine-synthetase]-adenylyltransferase/[glutamine-synthetase]-adenylyl-L-tyrosine-phosphorylase	gnl|CDD|237613	PRK14109, PRK14109, bifunctional [glutamine synthetase] adenylyltransferase/[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase.	0
NZ_CP047147.1|WP_008409231.1|1704722_1706006_-|extracellular-solute-binding-protein	gnl|CDD|270454	cd14751, PBP2_GacH, The periplasmic-binding component of the putative oligosacchride ABC transporter GacHFG; possesses type 2 periplasmic binding fold. This group represents the periplasmic component GacH of an ABC import system. GacH is identified as a maltose/maltodextrin-binding protein with a low affinity for acarbose. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.94585e-153
NZ_CP047147.1|WP_159312095.1|1709063_1710644_-|amidohydrolase-family-protein	gnl|CDD|238625	cd01300, YtcJ_like, YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling.	4.98059e-110
NZ_CP047147.1|WP_159312102.1|1726147_1726906_-|UTRA-domain-containing-protein	gnl|CDD|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	2.37326e-48

Protein sequences

>NZ_CP047147.1|WP_159312097.1|1717610_1718195_+|pyridoxamine-5'-phosphate-oxidase-family-protein
MGTHPDTDADTNTTAAAPAGHGGPAQGPVSTTLDPRYSTPDAEAVPWSTAEDLLHRSEVFWLTTVRPDGRPHVTPLLAVWQHGALHFATGAEERKARNLAQNQQVILTTGTNTLSDGLDLVVEGEACLVSDTDRLTSLATAWSTKYGPDWAFEVADGTFHHPDGASALVFAVPPHQIFGFTKGTPFSQTRWNFT
>NZ_CP047147.1|WP_010637478.1|1714324_1717330_-|bifunctional-[glutamine-synthetase]-adenylyltransferase/[glutamine-synthetase]-adenylyl-L-tyrosine-phosphorylase
MTIPQGRRSSTFTRLLRHGFTDPSTAERLLGSEALAPVAEDTVLLDALAATADPDLALLGLVRLAEAEPEEERQRLLSTVVTAKPLRDRLLGVLGASEALGDHLARHPQDWRALAIYESADLHPGVEEFTRGLADATDPDSLRVAYRRCLLSIAARDVCGTIDVAETAAELADLATATLRAALRIAEAAAPEDAARCRLAVIAMGKCGGHELNYVSDVDVIFVAEPADSGDADEAPALQAANRLAAHLMRICSETTVEGTIWPVDANLRPEGRNGPLVRTLSSHLAYYQRWAKTWEFQALLKARPVAGDAELGAAYIETIAPLVWQAAERDNFVPDVQKMRRRVVDTIPAHEIERELKLGPGGLRDVEFAVQLLQLVHGRSDPSLRSGTTLDALAALAAGGYVGRTDAAQLDDAYRFLRSMEHRIQLYRLRRTHLVPEGEADLRRLGRSLGLRTEPVVALNRAWRRHAGVVRRLHEKLFYRPLLDAVAQLAPGEARLSTEAARERLVALGYDDPSDALRHLEALASGVSRKAAIQRTLLPVLLGWFADSADPDAGLLNFRKVSDALGQTPWYLRLLRDEGAAAENLARVLSAGRLAPDLLMRAPEAVALLGDVRGLEPRGRAQLEQEVLAAVRRSDNAEHAVAVARGVRRRELFRTAAGDLIGSYGTEESPAEADPGALVDRVGSALSDLNAATLAGTLRAVVRDGWGDTLPTRFTVIGMGRFGGHEQGYGSDADVLFVHEPREGVDEQEAAKAANRVVAELRRLLEIPSADPPLVIDPDLRPEGKTGPLVRTLASYAAYYRRWSQVWEAQALLRAEPVAGDDELGARFVELVDPLRYPAEGLGEDGAREIRRLKARMESERLPRGADPTLHTKLGRGGLSDVEWTVQLLQMRHGAAEPGLRTTSTRPALAAAVAAGLLPAEEAAMLDEAWVLATRVRNAVMLVRGRPGDTFPSDGRELAAVARYLGYEPGHVGDMLDDYRRTTRRARAVVDEVFYGAGAH
>NZ_CP047147.1|WP_159313867.1|1712984_1713905_-|hypothetical-protein
MAGAGTPVPRQSFWRRWWKAGVVGVVCVLVVVVGLSLPGEEEGEAGPPPRNARTVAAVDLGTWDCLVTQELLELSPADSRTVGEVTVADCGGPHGGEVFSRVSLVGTAAENEDGTFRGTAQAEDAARAACAEEFAEGMTDPYSHDFTVRVIHPASSEEWTVRQSAACWVSARGLPEYCLVCETKLTDDQEAFRRALVPYTRAWAGRPPEDASLGARRAWASTMGRGIEEAAWLLRGKPELRRLGPEAGEDLADALTAQIPYWREAAAAKDPGAHEKAVTEAELAHSAGGEVARARDLIGLAPVITE
>NZ_CP047147.1|WP_018470689.1|1712345_1712960_+|TetR-family-transcriptional-regulator
MGRPRTPLIDRPRIATVALELVDANGEFSVPAIARRLGVQTGSLYHHVDGRDGVIELIRERVTEAIDVSALSAPTWDTALQDWARSYRAAFAAHPKVIPLLTTHPVRAPGMLDQYERVVRVLMDAGFATVDVMPLITALENTVLGSALDLAAPETMWEPADTTSTPRLSQALAAIGEGRADAAFEIALAAFMGYARGVLEGYEG
>NZ_CP047147.1|WP_159312096.1|1710675_1712163_-|amino-acid-permease
MSVPPQPPPPPHPAAPGLRAGTLTTADISFFVVSAAAPLTVMAGVAPIAIMLGGIGAPAGYLLAGITLTVFAVGFTTMSRHVGHGGGFYAYITRGLGRPAGMGAALLAMLGYNGMEIGVYGLLGSASQDTALALFGVEIPWLPVSLAGLVLIWYLGYRSIDFGAKVLGVLLVAETGILLLLAGGVLLDGGASGLTLDSFTPANVAVPGMAAVLACAFAAFTGFESTAIYRREARDPRRTIPRATFIAVAFLGLFYAFIVWTVIQAYGSDKVVQAATDDAGGLFFAAITTYVGGWAADLMHVLIVSSVIASLLAFHNAINRYTLSLTEEGLLPPVLGRIHPRHRSPYLAGAAQTAVGAVVVAGFALAGADPYTQLLLWVNTPGMIGLMALQLLAAAAVLGYFRRARHQEGVWRTVVAPVAAIALLGAALALVTANVELFSGAGTGTNIVLVSLVPAVFVLGVALALRLRRTRPEVYARFAAEPEGETPAAREPATR
>NZ_CP047147.1|WP_159312095.1|1709063_1710644_-|amidohydrolase-family-protein
MPAADLVLTAARVHALDPARPRAEAVAVKDGTIVAVGDRTDTADWTGPGTDTVDLGAATLTPGLVDAHSHPVWGLEMAAGTDLSAVTGLDGLRAALHTATPTDGWLLGWGLDHNAFGDQPLDRRPIEDIHPGVPVFLRLYDGHSALVNGAALDRAGITGPRTFGQRASVVCDAGGRPTGHLIEHAAMDLVQPHLPTPSDAERIARLRTLLGEMAATGLTGAHVMDLGDGTVPELLTAFETEGELPLRLRLAPWCMPGSTPADLAELIALQSRAGRLWRVGGVKFFMDGTVEGGTAWLEHADCHGQGTDAFWPDPEAYSAAVRTLDAAGVGTATHAIGDAAVRHVLDTVATLGPGARGRHRIEHIETVPDDQLPRFAELGVAASMQPPHTAYTRADHSDAWSRRLGPERAGRAWRIRELREAGAYVALGSDWPIAHHDARQVLALAQEPRGAARRGGGLSALMALEGVTSHAAAAAGEADVAGRIAPGHRADLTAFAADPLTTPAGELPGTPIALTVVGGSVRHRAV
>NZ_CP047147.1|WP_003947735.1|1708630_1709044_+|hypothetical-protein
MTKDHDDGRPDPAHRRPGEMSDTAVEALGALSKALETTERARGHLYSFHQLTGTADFQLDEAVRLLREAGHAEEAERVRTELVGRNVTPGHWTFQLVEEYDDGYYRPFAALEAELTDRLAGGRRHLHEAELKRRRRS
>NZ_CP047147.1|WP_093847066.1|1707536_1708505_+|phosphatase-PAP2-family-protein
MGPAGRSTRPAGPLGRLRTPRRPRIWFEILLIAVSYWVYSLIRNAVPEQKAQAMANADWIWEAEQRLGIAVEHGVNHAVNSVTWLIVGMNYYYATLHFVVTLGVLVWLYRRHPGRYAAARTVLFATTAVALVGYYLYPLAPPRLMNGQHFIDTVLVHQTWGSMASGDLKHMSNQYAAMPSMHIGWSLWCGLTIFALASVPWAKVLGLLYPALTLVVIVATANHFWLDAVGGLACLLFGYLVARLCYGALPKGLPQQVPDGRREATAPPAAAPTPPAPGPARSTEPPPAEEHPVPSPTGPGPRGATALTRASPEPSPAPAPES
>NZ_CP047147.1|WP_159312094.1|1706334_1707408_+|substrate-binding-domain-containing-protein
MTARLADIAAQAGVSEATVSRVLNGKQGVAAATRESVLAALDVLGYERPVRLRRRSAGLVGLITPELENPIFPALAQVIGQALTRQGYTPVLATQTPGGSTEDELTEMLVDRGVSGIIFVSGLHADTTADMARYDRLRGQGVPFVLIDGFTDQVRAPFISPDDRAAMRLAVTHLASLGHTRIGLALGPKRFVPVVRKTEGFTRALHDTFGIDAAEAGREFVRHSLYTLEGGQAAADSLLDGGCTAVVCASDMMALGAIRAVRRRGLDVPADVSVVGFDDSPLIAFTDPPLTTVRKPVTAMGQAAVRALLEEIGGTPAPPSEFVFMPELVVRGSTASAPPPDAPGVGEVPQREIVRKA
>NZ_CP047147.1|WP_008409231.1|1704722_1706006_-|extracellular-solute-binding-protein
MRRGIAATALVASLALAATACGGDTTDESGAKGGKSGGELAGTVTWWDTSTVGSEDKVFKALAEGFEKEHPKVKVNYVNVPFADAQNKFKNAASSGSGAPDVIRSEVAWTPDFASLGYLAPLDGTAALDKEDDYLKQAAASTKYDGKTFGVPQVIDSVGIFYNKKLLKEAGVEVPKTLDELTEAAKAIKSKTGKAALYLRGDDAYWFLSFLYGEGGDMINTKDKSVTIDDKPAIDAFKAVKELVDSKAAVTDATNGWDNMQKAIKDGEVAMAINGPWAVTDTLAGDAFKDKANFGVAPVPAGSKTAGSPQGGHNYAVYAGSKNLDASYEFVKYMSSAKVQAEVTEKLSLLPTRASVYGEPKVADNEIVQFFKPVVETAVERPWVPEGGSLFAPLQTQYTKVLTGQATPEQAAKSTGDSYRKLLKDYK
>NZ_CP047147.1|WP_159312098.1|1718509_1720117_-|MFS-transporter
MSAHSAAAPTAAAPMDHRHVMRAFSGLLVVLFVAMISGTVVSVALPQIIGSLDGTQSQYTWVVTATLLASTASTPIWGKLADLFSKKLLLQIAIGLFIVASLACGFAQNTGQLIGFRVIQGLGMGALQVLVQVIIAAMISPKERGRYNGYLGGVMAVATVGGPLLGGFITDTSWLGWRWCFFIAVPFTLIALVMLTRTLHLDEIKRPDTKVDYLGAALIAAGVSLLLLWVTFVGNNFDWISWQTLAMVAGSVLLLGAAVMVEAKVAEPIVPLHVVRRRDPALAIIASLAVGMAMFGGAVFLGQYFQIGRGYSPTEAGLLTIPMMAGVLISSTVAGRLVSKSGKVKPYIIAGVVLLTVGFLGLSLIDHKTSLVGVSLGMLAVGAGVGMPMQNLVLVLQNTVPLSELGAASGSITFFRSLGGTVGVSVLGAVLANQVSAKIADGLSRIGVDPAAGGSGSGTLNIAAMPPQIQEIVRAAYGEATGHIFLISAGIALIGVVATLFLTPTRLRDSVDLADGSGDAGGAGEAGERVPAAAG
>NZ_CP047147.1|WP_059212806.1|1720236_1720860_+|TetR-family-transcriptional-regulator
MDSTEETPAATPDAPLGLRERKKAATRQAVHEAAMRLTREHGLDHVTVEAIADAAGISRRTFSNYFAGKEDALLYGKEQYIQRLLDAVRDRPAEETNWQALRAATQVLRDPRLDPPRREWAQQTRLAMGHPSLLGRQLSTLATLESDLAATLTARSPTDPVRARVMAAAFLVALRIAMQLWIEENEQAEDPMELMMITMDEMGARFV
>NZ_CP047147.1|WP_018470694.1|1720958_1721330_-|hypothetical-protein
MSEVDGARLFREGWIAGVRRHFPGEPKAGYVTPWEGTPEWEREAAGAVCAQVRQFVEVSAGKAGRLSREQKGRFVATCWTAQMYKHFEEPKPGYVADWAELPKWQQETDADIFEAIERHFPPS
>NZ_CP047147.1|WP_159312099.1|1721344_1722598_-|helix-turn-helix-domain-containing-protein
MGLAERRRARGYSQEKLAHLLGVDRTTVGRWESGRVFPQPPQRRGLAHALGLSLDELDCLLAMPAVRVQETARCQTEESPTPGDSDEMMRRAFLRVLSVSGALAVLPVHEAEALQEEAGLGASADFDRMSGHLWQVYQLARSKKAVHPVVRDQLSMLNEALASGRGPTRSLLSAAADLFQLAGEVAFDGNRYSEAASSYALAASVGREADAYDLWACALVRHAYVEMSEGRHRQAVQLLGAAARLARRGDSALSTRQWVASVQAEAYAGLGDLTACERAMDQAETVRELAGGSANGGWLRFDGARLSEERGARYVQLGRFDRAEETLTGALKQSDLAAGHSYRRRGAVLTDLAVIGVRRGDAEQVVAYGGEAVGLARATGSGYVVHRLQALRGELGSLSEDRRVAGLGAEIAALGMS
>NZ_CP047147.1|WP_159312100.1|1723961_1725008_+|DUF262-domain-containing-protein
MLLDEAGLLNELDRHRRSVDTDYFDLSLRELVRMVSEQEIKIAPAYQRQFRWDDETQSALIESFLLGLPVPAIFVATNRDATWDVVDGLQRICTVLRFMGIDAPESDKFRFSVTPLRLKSLKTLSGFGDLTYEELPRPIRMTLDRRFLRVQVLSDKSEPEVRFELFRRLNAGAVALTSQEIRSCIFRGPFHELLEDLSQNREFKSLLKLQKLNQTNGTPEELVLKFFAYLDRSTEFDGRVSNFLNNYMRDRASDSDLAVDREIFEKSVSFLFSINPGPFLRGKLSITPLNQFEAVLVGLGSLFRRGVTPRTPPSGWLNDEKLVNFSTGATNTRTMLLNRISRAEELMS
>NZ_CP047147.1|WP_159312101.1|1725022_1725691_+|hypothetical-protein
MESVFSDAVERLARERRRLEHLSTQVEPQSFDRDGFLAMGRALSYVVMGGVLECLMRDLPRALATDVAALKIQRNSLPLGLVAALEAAAFRKCGDGTIGALLARTAILQGAVDHSADLRLVEDFSDSLKLADGSTVGQKNFEALWALLNLPGEWRNSPNDVFLLREIKDKRNDVAHWEADPVDVGRSKRPTSLIEMVDQLIALLDHALLHICYWFEERSTAP
>NZ_CP047147.1|WP_159312102.1|1726147_1726906_-|UTRA-domain-containing-protein
MASTNGDRRPKYQRIADTLREAIQAGEYGPGDRLPGENDLMATHEVARMTARQALGVLQAEGIAESRKGAGVFVRAFRPLRRRGIQRLAQEQWGAGRSIWAADTENRDLVVDQVEVTEEPAPERISVVLDVEAESKVCVRRRRFVLDGKPVLLATSYLPAPIVAGSAITEENTGPGGVYARLAELGYKPVHFREEIRSRMPSKDEATQLNISAGTPVILICRTAFADEGRPVEINEMTLDAASYVLEYDFDA
>NZ_CP047147.1|WP_008413651.1|1727097_1727433_+|hypothetical-protein
MPSFKIDVSTAVVFVATAPTPKLVNKQTGERAVDRETGAGLSTVGLLISDEGEGNLYQVTVPETGLPEGLTPGMPVSVVGLKARDWENEFNGQKRHGISFRAVAVTSMAGA
>NZ_CP047147.1|WP_159312103.1|1727435_1728776_+|plasmid-transfer-protein
MTDLPLWLEAAGAVSAAGGLGVAKYRAPRLYWSTVGMPVASARFTWTYRSVMDVCDLTVQPSRLRAFMVRNVARREVQPVPPKVRRLRGTSTGLRVTLRLPAGLEPADVAAASERLRHAWGVHSVTVVETKPGFVELRMTGYDVLRRVRMPRKAQPRDLVVPVALREDGTPFVRDFRKVPHGLTLGANQSGKSMYQRNLVKGLAGLPVALVGIDCKRGVEQAGYAPRLSALATTSDDADRLLAVLVREMEERFDLIASHGVADLWELPAKARPVPVVVLVDEVAELFLTASKKDEERRERLVTSLIRLAQMARAVGIYLEVCGQRFGSELGKGATMLRAQLTGRVVHRVNDKQTAEMGLGDVAPDAVPVVTSIPPDRPGLAVAADASGGWSRIRTPLTTPADAVAACRKYAHLVPHLPALAPFRPPAPVVEPSPGGSLVRPFPVTE
>NZ_CP047147.1|WP_159312104.1|1728957_1729695_+|DUF2637-domain-containing-protein
MSRMKLDAVLVQAVIAGSLSFAHIHDVADAAGQDGWKAWAYPISVDLLLVAAWRRLRTFRGDRTAWFWFGVALVASLGANVATAGLLDLTDVPAWLRILVAGWPALAFLGGSLLIHQPDPEPDTAPKPGHEAAAGENPVVLERDEAPAAPALPAPAQAPAESMPTAEQPEPVPQPAQVPETPAPAPPAVKLPVPSVPPALLDHARKVADAHRASTGQPMPAATLRDRLGLPEPLANAITSELQLA

Crispr_ID: NZ_CP047147_7

• CRISPR_ID: NZ_CP047147_7
• CRISPR_location: 2587174-2587324
• CRISPR_type: Orphan
• Repeat_type: I-C,I-E,II-B
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP047147_7

Consensus_repeat	Method
GTGGTCCCCGCGCACGCGGGGGTGATCCC	CRISPRCasFinder

spacers of NZ_CP047147_7

>7.1|2587203|32|NZ_CP047147|CRISPRCasFinder
TACCTCGTCCTCGACGAGCTGTGGCGCGTCCT
>7.2|2587264|32|NZ_CP047147|CRISPRCasFinder
GAGGCCGCTCCGGTCGTCACGAACATCATCGA

CRISPR arrays and Neighbor proteins around NZ_CP047147_7

CRISPR arrays

The CRISPR arrays of NZ_CP047147_7

>merge|NZ_CP047147|7|2587174-2587324|CRISPRCasFinder
GTGGTCCCCGCGCACGCGGGGGTGATCCCTACCTCGTCCTCGACGAGCTGTGGCGCGTCCTGTGGTCCCCGCGCACGCGGGGGTGGTCCCGAGGCCGCTCCGGTCGTCACGAACATCATCGAGTGGTCCCCGCGCAGGCGGGGCAAGCCCC

>NZ_CP047147|7|6|2587174-2587324|CRISPRCasFinder
GTGGTCCCCGCGCACGCGGGGGTGATCCC	TACCTCGTCCTCGACGAGCTGTGGCGCGTCCT
GTGGTCCCCGCGCACGCGGGGGTGGTCCC	GAGGCCGCTCCGGTCGTCACGAACATCATCGA
GTGGTCCCCGCGCAGGCGGGGCAAGCCCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_010638599.1|2592090_2593341_+|sugar-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270450
NZ_CP047147.1|WP_003948481.1|2594293_2595127_+|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl|CDD|223472
NZ_CP047147.1|WP_159312350.1|2583612_2584191_-|hypothetical-protein	unknown	unknown	gnl|CDD|240430
NZ_CP047147.1|WP_067412570.1|2581670_2582204_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379112
NZ_CP047147.1|WP_008410798.1|2578284_2579112_-|trypsin-like-peptidase-domain-containing-protein	unknown	unknown	gnl|CDD|379142
NZ_CP047147.1|WP_003948467.1|2579549_2580047_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159312353.1|2588631_2589510_+|aminopeptidase	unknown	unknown	gnl|CDD|176450
NZ_CP047147.1|WP_159312352.1|2586009_2586558_+|carboxymuconolactone-decarboxylase-family-protein	unknown	unknown	gnl|CDD|225039
NZ_CP047147.1|WP_129819662.1|2582248_2583469_-|glutathionylspermidine-synthase-family-protein	unknown	unknown	gnl|CDD|367631
NZ_CP047147.1|WP_159312354.1|2589559_2590414_-|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|223669
NZ_CP047147.1|WP_129839713.1|2596484_2598005_+|VCBS-repeat-containing-protein	unknown	unknown	gnl|CDD|379232
NZ_CP047147.1|WP_003948475.1|2587484_2588594_+|LacI-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224525
NZ_CP047147.1|WP_018894274.1|2598065_2598530_-|VOC-family-protein	unknown	unknown	gnl|CDD|319898
NZ_CP047147.1|WP_008410790.1|2586698_2586911_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_008410772.1|2595194_2596388_+|family-1-glycosylhydrolase	unknown	unknown	gnl|CDD|274539
NZ_CP047147.1|WP_003948480.1|2593346_2594297_+|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|224096
NZ_CP047147.1|WP_003948468.1|2580404_2581658_+|ornithine--oxo-acid-transaminase	unknown	unknown	gnl|CDD|179736
NZ_CP047147.1|WP_003948464.1|2577357_2578194_+|DUF1206-domain-containing-protein	unknown	unknown	gnl|CDD|377695
NZ_CP047147.1|WP_159312356.1|2590548_2591448_-|acetylxylan-esterase	unknown	unknown	gnl|CDD|225989
NZ_CP047147.1|WP_159312351.1|2584475_2585903_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl|CDD|224089

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_003948481.1|2594293_2595127_+|carbohydrate-ABC-transporter-permease	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	2.0156e-89
NZ_CP047147.1|WP_129839713.1|2596484_2598005_+|VCBS-repeat-containing-protein	gnl|CDD|379232	pfam13517, VCBS, Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella. This domain of about 100 residues is found in multiple (up to 35) copies in long proteins from several species of Vibrio, Colwellia, Bradyrhizobium, and Shewanella (hence the name VCBS) and in smaller copy numbers in proteins from several other bacteria. The large protein size and repeat copy numbers, species distribution, and suggested activities of several member proteins suggests a role for this domain in adhesion (TIGR).	2.80391e-05
NZ_CP047147.1|WP_067412570.1|2581670_2582204_-|GNAT-family-N-acetyltransferase	gnl|CDD|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	7.48041e-13
NZ_CP047147.1|WP_008410798.1|2578284_2579112_-|trypsin-like-peptidase-domain-containing-protein	gnl|CDD|379142	pfam13365, Trypsin_2, Trypsin-like peptidase domain. This family includes trypsin-like peptidase domains.	7.11501e-07
NZ_CP047147.1|WP_159312353.1|2588631_2589510_+|aminopeptidase	gnl|CDD|176450	cd08663, DAP_dppA_1, Peptidase M55, D-aminopeptidase dipeptide-binding protein family. M55 Peptidase, D-Aminopeptidase dipeptide-binding protein (dppA; DAP dppA; EC 3.4.11.-) domain: Peptide transport systems are found in many bacterial species and generally function to accumulate intact peptides in the cell, where they are hydrolyzed. The dipeptide-binding protein (dppA) of Bacillus subtilis belongs to the dipeptide ABC transport (dpp) operon expressed early during sporulation. It is a binuclear zinc-dependent, D-specific aminopeptidase. The biologically active enzyme is a homodecamer with active sites buried in its channel. These self-compartmentalizing proteases are characterized by a SXDXEG motif. D-Ala-D-Ala and D-Ala-Gly-Gly are the preferred substrates. Bacillus subtilis dppA is thought to function as an adaptation to nutrient deficiency; hydrolysis of its substrate releases D-Ala which can be used subsequently as metabolic fuel. This family also contains a number of uncharacterized putative peptidases.	4.25351e-122
NZ_CP047147.1|WP_159312350.1|2583612_2584191_-|hypothetical-protein	gnl|CDD|240430	PTZ00473, PTZ00473, Plasmodium Vir superfamily; Provisional.	0.00526015
NZ_CP047147.1|WP_129819662.1|2582248_2583469_-|glutathionylspermidine-synthase-family-protein	gnl|CDD|367631	pfam03738, GSP_synth, Glutathionylspermidine synthase preATP-grasp. This region contains the Glutathionylspermidine synthase enzymatic activity EC:6.3.1.8. This is the C-terminal region in bi-enzymes. Glutathionylspermidine (GSP) synthetases of Trypanosomatidae and Escherichia coli couple hydrolysis of ATP (to ADP and Pi) with formation of an amide bond between spermidine and the glycine carboxylate of glutathione (gamma-Glu-Cys-Gly). In the pathogenic trypanosomatids, this reaction is the penultimate step in the biosynthesis of the antioxidant metabolite, trypanothione (N1,N8-bis-(glutathionyl)spermidine), and is a target for drug design. This region, the pre-ATP grasp region, probably carries the substrate-binding site.	1.46292e-172
NZ_CP047147.1|WP_159312354.1|2589559_2590414_-|alpha/beta-fold-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	2.12175e-15
NZ_CP047147.1|WP_003948475.1|2587484_2588594_+|LacI-family-transcriptional-regulator	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	6.77364e-89
NZ_CP047147.1|WP_003948468.1|2580404_2581658_+|ornithine--oxo-acid-transaminase	gnl|CDD|179736	PRK04073, rocD, ornithine--oxo-acid transaminase; Provisional.	0
NZ_CP047147.1|WP_010638599.1|2592090_2593341_+|sugar-ABC-transporter-substrate-binding-protein	gnl|CDD|270450	cd14747, PBP2_MalE, Maltose-binding protein MalE; possesses type 2 periplasmic binding fold. This group includes the periplasmic maltose-binding component of an ABC transport system from the phytopathogen Xanthomonas citri and its related bacterial proteins. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.70213e-130
NZ_CP047147.1|WP_008410772.1|2595194_2596388_+|family-1-glycosylhydrolase	gnl|CDD|274539	TIGR03356, BGL, beta-galactosidase.	5.76e-83
NZ_CP047147.1|WP_003948480.1|2593346_2594297_+|sugar-ABC-transporter-permease	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	1.31685e-90
NZ_CP047147.1|WP_159312352.1|2586009_2586558_+|carboxymuconolactone-decarboxylase-family-protein	gnl|CDD|225039	COG2128, COG2128, Uncharacterized conserved protein [Function unknown].	3.16539e-27
NZ_CP047147.1|WP_018894274.1|2598065_2598530_-|VOC-family-protein	gnl|CDD|319898	cd06587, VOC, vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). Type I extradiol dioxygenases catalyze the incorporation of both atoms of molecular oxygen into aromatic substrates, which results in the cleavage of aromatic rings. They are key enzymes in the degradation of aromatic compounds. Type I extradiol dioxygenases include class I and class II enzymes. Class I and II enzymes show sequence similarity; the two-domain class II enzymes evolved from a class I enzyme through gene duplication. Glyoxylase I catalyzes the glutathione-dependent inactivation of toxic methylglyoxal, requiring zinc or nickel ions for activity. The antibiotic resistance proteins in this family use a variety of mechanisms to block the function of antibiotics. Bleomycin resistance protein (BLMA) sequesters bleomycin's activity by directly binding to it. Whereas, three types of fosfomycin resistance proteins employ different mechanisms to render fosfomycin inactive by modifying the fosfomycin molecule. Although the proteins in this superfamily are functionally distinct, their structures are similar. The difference among the three dimensional structures of the three types of proteins in this superfamily is interesting from an evolutionary perspective. Both glyoxalase I and BLMA show domain swapping between subunits. However, there is no domain swapping for type 1 extradiol dioxygenases.	9.37741e-15
NZ_CP047147.1|WP_003948464.1|2577357_2578194_+|DUF1206-domain-containing-protein	gnl|CDD|377695	pfam06724, DUF1206, Domain of Unknown Function (DUF1206). This region consists of two a pair of transmembrane helices and occurs three times in each of the family member proteins.	6.2428e-13
NZ_CP047147.1|WP_159312356.1|2590548_2591448_-|acetylxylan-esterase	gnl|CDD|225989	COG3458, COG3458, Acetyl esterase (deacetylase) [Secondary metabolites biosynthesis, transport, and catabolism].	1.82511e-54
NZ_CP047147.1|WP_159312351.1|2584475_2585903_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl|CDD|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	8.38382e-106

Protein sequences

>NZ_CP047147.1|WP_008410790.1|2586698_2586911_-|hypothetical-protein
MLTTTRPRTTPVPPPCPDRACHTDIHGRLWKDTTYLRNDPDNWRWYCSRCGQHWMPTHEQFAWYRTLPVA
>NZ_CP047147.1|WP_159312352.1|2586009_2586558_+|carboxymuconolactone-decarboxylase-family-protein
MTTENTPTAPSTSTTPTTPDEKAAAYLPEHTPRISVAELAPDLYRALARADAAARKNLDPVIGELVKIRASQINHCAFCLDMHTKDALAMGESVERIVQLSAWEESKHYYTAKEIAAIELTEAITVLTDGFVPDEVYAQAAAHFDENELAHLIGAITVINAWNRLSVAARNVPGHYVPGSLG
>NZ_CP047147.1|WP_159312351.1|2584475_2585903_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MTESWANLGIDLHLEPAGPGLRKGLTDALREAVRSGRLAPGTRLPSSRTLAGDLGIARNTVADAYADLVAEGHLTARQGSGTRVAEQAGPASSVPRRQRPVRVPERAGPAHDLTPGTPDLSAFPRAAWLKAARRALTAAPNDAFGYGDPRGRPELRAALAEYLARVRGVAADPERIVVCAGVAHGLKLVTEVLAARGGHGGRQGAGTVAVETYGLRFHREWLAEEGVGTVPLPFDAEGTDPAGLDGERAVLLTPTHQFPMGGTLSPARRAAVVDWARRTGGLILEDDYDGEFRHDRRPVGALQGLAPDRVAYFGTASKALAPGLRLGWLVLPPTLVDEVLAAKGYADTCGAPDQLTLAEFLTSGAYDRQVRLMRLRYRRRRDELVATLARRAPSVRVGGIAAGLHAVLLLPPGTESEVLRAAAWHGLGVQGLSWFRHPDAEAAGRPVPEGLVIGYGRPPDHAWQSALETLCRCLP
>NZ_CP047147.1|WP_159312350.1|2583612_2584191_-|hypothetical-protein
MAENITVPAVRALDAPVARPATGPGRGAAPQGVPVADERPPAPVRLTKSGAGEPGSGSGEPSAEKRRKKAARRRVRSSTVALGSMGVLAAALAACGSEPDRRCVDRNSYSYGGGYKVVDSSQCRNGSSGSTGGTGGGGSSGGSGRYGSDRSSNAGWYYGGDSKSGYASDGSFNKSSVSSGGFGCSGKGSGGG
>NZ_CP047147.1|WP_129819662.1|2582248_2583469_-|glutathionylspermidine-synthase-family-protein
MQRHTIEPRPGWQETVEAQGVIYPLTRHPDDSLRPYWDESAYYSFSLAEVEALEEVVEELHAMCLAAAAHIVEKDRFAELGITDPRLASLVTEAWHRKAELPSLYGRFDLWYDGSGAPAKMLEYNADTPTSLVEAASAQWFWMEERFPGADQWNSLHERLVDAWRAQAALLPPGSPVHFAHTIDDECGEDLMTVAYLRETAAQAGLETEAIAVEDIGWDSLSHRFVDQRLRFIRSCFKLYPWEWLATDDFGPHVLDTLDNGGGTGSTLWIEPAWKMLLSNKALLAILWELYPGHPNLLASYLDGPRELAATTGYVTKPLLGREGAGVTLHQPGGTQTPAPATGPSCYQQLALLPDLSTPAPGAHSPTNHVVLGAWVVADEAAGLGIRESAGPVTDGYARFLPHVIL
>NZ_CP047147.1|WP_067412570.1|2581670_2582204_-|GNAT-family-N-acetyltransferase
MPELQRLRADHAPALLAFERENRAWFARTISDRGDAYFADFPARHRALLTYQDEGTDHFHVLVADDATTILGRFNLMDITDGQAELGFRMAESATGRGLATEAARTVCHLAATAYALTSLRAQANLDNLASHTVLTRTGFTATEQTVLRNGTAGRRYVKELAGPEEGAARAIGAAGL
>NZ_CP047147.1|WP_003948468.1|2580404_2581658_+|ornithine--oxo-acid-transaminase
MSGTPSGTHSSPAPGSATAEAIDAAEAHSAHNYHPLPVVVASAEGAWMTDVDGKRYLDLLAGYSALNFGHANPRLIAAAKAQLDRVTLTSRAFFHDRFAAFCEELAALCGKDMVLPMNTGAEAVETAVKTARKWGYRVKGVPDGAARIVVASGNFHGRTTTIVSFSTDEEARADYGPYTPGFDVVPYGDADALEAALTDDTVAVLLEPIQGEAGVLVPPAGYLRRVRELTAERNVLFIADEIQSGLGRTGRTFACEHEGVVPDLYLLGKALGGGVVPVSAVVGDSDVLGVFRPGEHGSTFGGNPLACAVALEVIAMLRTGEYQARATELGTRLHNALADLVKADGPVRAVRGRGLWAGVDLDPAVGTGREISERLMSRGVLVKDTHGSTIRIAPPLVISAEDLDWGLGELRGVLGMA
>NZ_CP047147.1|WP_003948467.1|2579549_2580047_-|hypothetical-protein
MSALDFCAEVLIEGRIRGAGLGDSMAVWDRCMGYEYTDGLSRGRLRRDYGLVEIIFEQYDTGWHATGIEIQAYRLGRFGVGIVPQVLAPYFGAVESRVNAKELLETVAAKGFGIEAVHEEGARTHAYRVDSSGGVVYVLMAETRSMKVPSVGDVWTVVLELPDEE
>NZ_CP047147.1|WP_008410798.1|2578284_2579112_-|trypsin-like-peptidase-domain-containing-protein
MKKPLAGALLAAALLGASAAPAVAAPGPAAPAAVDLAGTVALSNCSGSVVRAPSASADDPALVLSNGHCLETGFPAPGEVLVDQPSSRSFTLLDGAGNGVGTLRAAKLAYGTMTDTDVSLYQLGESYAEIESAYGIEALELDAARPSEGAAITVASGYWKRTYNCSVDGFAHQLKEGSWTWKDSVRYTDACDTIGGTSGSPVIDDATGKVVAVNNTGNESGGRCTDNNPCEVDENGEVTVREGINYGQQTYTLVPCIGPGSEIDLGREGCAVPKP
>NZ_CP047147.1|WP_003948464.1|2577357_2578194_+|DUF1206-domain-containing-protein
MNSSSMAREGHRQARRAADSKVVSAGARAGFAARGVIYLLVGLLAGQIAFQGDGKQADRGGALQEISGQPFGGILLWVIGIALVGMALWRLSEAAFGAAGPDGDKAMKRVVSGARAVFYAFVAYSVLSFAAGEKSGGGSSDKQSQDITAQALGLPGGQWIVGVAALGVAVAGVVVGARAVMRKYHKHLRMGAMSRRARQFVDVTGVFGGAARGLVFAAAGVFAVTAAVDYDPDEAKGMDDTLRSFADTPAGPWLLVLVAVGLAAFGLFSFANAKWRKV
>NZ_CP047147.1|WP_003948475.1|2587484_2588594_+|LacI-family-transcriptional-regulator
MGDGVAGTPTVYDVAGRAGVSIATVSRVYRSPESVREATREKVLVAARELGYVPSGSARGLASRSTGVLGLCFPDYSDPDAESEAATVDADDDHAFMLYSDQIIRGMERAARRHGYALLIAASLTGGPESLVAKVAGRVDGCAVLARTVPTEDLEVISRRLPVVMLAGPPEQDGPGGLDRLDHIEVANAEGQRELTRHLIEDHGLRRLTFVGGIEDSPDAEARFAGFRDACRAAGLPVPDEPDLRAELMTQAGGARAAEELVDRAGPDGLPEGVLFANDQMAVGALHALARRGLRVPEDLAVTGFDGIPLGRLVQPTLTTVRQPMRRLGEEAVELLVRRLAEEKRGEPESLVLPVEVVRRASCGCGHEA
>NZ_CP047147.1|WP_159312353.1|2588631_2589510_+|aminopeptidase
MDNHGSTGEDPTSEAKGPRILISVDMEGVSGIVHPRETHPDGYDYGRARALMTAEANAAVAGVLDAEPGAEVWVADAHGSYRNLLPEEVDRRARLVRGKPRPLGMLGGVDERTDAVLFVGYHVRAGAGPGVLAHTMSDALLDVRVDGRSLGEIALNAAMAGHLGVPVVLLSGDDAACAEVRELVPGVRTVAVKEALGQFAAAGLHPEEARERLRRTAAEAVAGREEVRPFALSGPQTVEVDLAAAHTVDLAVLIPGVTRAGGARTVTFTAADFGEAYRVVLLLVQLGSIRPA
>NZ_CP047147.1|WP_159312354.1|2589559_2590414_-|alpha/beta-fold-hydrolase
MSGASSRSSRSPGESRLPVHATVWDDRPNSGGSGSRWPVVLVHGILTWGTDPRYGFAAQRPLAARRRLLLMDRRGYGRSPDIARSDWAVDAEDIVELLGTGAHLVGHAYGGVGALAAAVRRPDLVRSLTLIQPGALRPAARHPVVAEALARARAATAALPPDLTPAGFLRGATESVGMETPEATPERLRAAATTMAELPCWDAEIDLGPLARAAFPQLLVSGDWEGAPEPYRTYAGLPLIACAEEIAAATGAAHLVVPGHYPHTQQPERVNAAMEHLWEAADQG
>NZ_CP047147.1|WP_159312356.1|2590548_2591448_-|acetylxylan-esterase
MPGGFAGFWRGRYEEALEVVTAPEVGAVEEVRDGVRVCRVSFSSVGGVRLGGWLALPVDGPAEHGFVVGHGYGGRDAPGPDLPLPLPRSAALLPCVRGMGERSRLPGVPTVADAHVLHGISSRDTYVIGACVADLWCAASALLELVPELARHPSGPRLGYLGESFGGGLGALALPWDDRFAAARLTVPTFGNHPLRLTLPCTGSGESVRRHHRDHPHVVDVLSYFDAATAATFVRVPTLVAAALFDPAVPPPGQFAVHNALPDDLRALHVLSAGHFDHPGAEEEAAGLARAEREFFTRL
>NZ_CP047147.1|WP_010638599.1|2592090_2593341_+|sugar-ABC-transporter-substrate-binding-protein
MHRVARTATAVIAASTALAVVTACGGSSGTEVAADAEQTLTVWAMGAEGEKLAEVAKEYEKENPHLKVKVTPVGWDVAHQKLVSAAAAGNLPDIAQMGGSYLGEFAELGVLEPVDTKRFQEKDFFPAGWQQGEVDGEVYGVPWYVDTRVLYYRTDLAEKAGVDKAPADWKELRALASAYQKDAGTKWGLSIQPSGLDTVQSFYPFLYSAGGEIIDEDGKVVVDSPAAVKALKEYGAYFDKGLANKSVPPGYDVVKDFGNGRVPMFFGGPWHVTLLNEGQPDIKGKWAVAEVPADEASVSMAGGSSLTVSKDSPHKAAAEEFIAHLTSTEGQADWYERTKDLPANTTAWESGSLADDPALKVFEKQMKTAKASPTLANLSEITDKVDQAIAQVTQGKATAEEALGKAKDQIEGLVQK
>NZ_CP047147.1|WP_003948480.1|2593346_2594297_+|sugar-ABC-transporter-permease
MSTTTRKADEAAPGGRRPGRRRGSLGVQNAAGWLFSTPFLVLFAVFMAFPIVATLLMSFTDFGLGNVTRPLDARFIGFENYTRLFGDERFLKSLFNTAYFVVVGVPLTIGLGLLVAVLLNNGIDRARTFFRVGFYAPVVTSIVAVAVVWRFVLDPSDGLIAGLASEVGLTAPDFLGSEALAMPSLIAMAVWRNLGTVMVLFIAGLQAIPTEVREAARLDGVGPWQELRRITIPLLRPTLLYASVITTIGYLNVFEEPFVMTQGGPSDSTLTVSLNMYREGFNFFHMGYASAMAYVLFVVIMGITVLQLRLLKDNTR
>NZ_CP047147.1|WP_003948481.1|2594293_2595127_+|carbohydrate-ABC-transporter-permease
MSAEGRVRRPLTYVLLSGGLLVMAAPFLWMGLSAFKTQRELSASPPVWIPSQWTLANFRQLLADLDLPLYFMNSVIVAVLVTVSNLVFCSMLGYALAKLNFAGRNKVFGVVLGALMVPGNLMLLPLFVLMSKLQLIDSYAGLVLPFAAGAFGVFLMRQFMQSIPDELLEAARMDGAGEWFIFWRIVMPLVKPALATLAILTFLGSWNNFVWPLIATNDPDKYTLPVALATFATDPNKAGGSNGVLMAGSFLIVLPVLAVFIALQRHFTQGIATAGMK
>NZ_CP047147.1|WP_008410772.1|2595194_2596388_+|family-1-glycosylhydrolase
MTSTPFPEGFLWGASTAAHQIEGNNTDSDWWVKEHTAGTHIQEPSYDACDSYHRWPEDMDLLASLGFTDYRFSIEWARIEPVEGHFSRAELAHYRRMVEGAIERGLRPMVTLHHFTVPQWFEARGGWTAEGATELFARYVAACAPVIATGVAHVCTINEPNMIAVMAGQAKRGDIGFPPAGLPTPDEETTHAVIAAHHAAVKEVRAISSGIKVGWTIANQVYQALPGAEEVTAAYRHPREDVFIEAARGDDWIGVQSYTRTRIGADGPIPASPEAERTLTEWEYYPTAVGHALRHTAEVVGDVPLIVTENGIATADDERRTAYYTGALGEVAAAIEDGLKVEGYLAWSALDNYEWGSFRPTFGLIAVDWETFERTARPSAVWLGSLGRTRELPGRAV
>NZ_CP047147.1|WP_129839713.1|2596484_2598005_+|VCBS-repeat-containing-protein
MAWMRRPDTPTTRRGRSGRAAASLAAALLVSGGLSAAALAPTTALAADGPAAASADDFNGDGYADLVSGAPGGTVSGKAGAGYVAVTYGSANGLAPAPGTVVSRSTAGVPGAATAKQRFGETFAKGDLDGDGYSDLVIGSATAEPGAVILWGSPKGLTGGTAVAGFGQAPQVGDFDGDGQADLALFGAAQVAGDDPVTQEARLLKGPLTREGTPAEQLDFLDRSEWWGYDSDGPACAEDDSCVDGPTSVGGPVRPKAVGDVNGDGSDDLVTWLYEGDGVWAHHLFTGSATGFRDAQEAGPIGSSGDDAAVGVGDVDGDGYDDVVTGSGEATAKVTVRYGSAAGLEGREQAFDQSLPGLHGAQEKGDHFGSCVAVADVTGDGRAEIALGISGEDFSGLTDAGSIALLHGTASGVTGEGSQVLHQNTAGVPGVAESGDKFGSACALLDTDGDGHRDLVAAAAEENEQAGAVWALRGTGEGLTVEGASAFGPGHVGGPVTKAKFGSFLR
>NZ_CP047147.1|WP_018894274.1|2598065_2598530_-|VOC-family-protein
MAEKSFPAPESGMLLSYFLTVADVPRSRAFYSEVLGGEVILEENPCTVRLANSWLIMNPGGGPTPDKPGITLHPPEDPATATCFLNIRVADIQAVYEEWSAKGAEFVTPPIDRKAEIRCYLRDPDGYLIEIGQATGMLHGVYADPPAGKGPGTQ

Crispr_ID: NZ_CP047147_8

• CRISPR_ID: NZ_CP047147_8
• CRISPR_location: 2614698-2614783
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP047147_8

Consensus_repeat	Method
AGCCCGGCCGGCGATTGAGGCCA	CRISPRCasFinder

spacers of NZ_CP047147_8

>8.1|2614721|40|NZ_CP047147|CRISPRCasFinder
TCAGTGACCGTCGGCCGAGGCATCACCTCAGCCAAACGAC

CRISPR arrays and Neighbor proteins around NZ_CP047147_8

CRISPR arrays

The CRISPR arrays of NZ_CP047147_8

>merge|NZ_CP047147|8|2614698-2614783|CRISPRCasFinder
AGCCCGGCCGGCGATTGAGGCCATCAGTGACCGTCGGCCGAGGCATCACCTCAGCCAAACGACAGCCCGGCCGGCGCTTGAGGCCA

>NZ_CP047147|8|7|2614698-2614783|CRISPRCasFinder
AGCCCGGCCGGCGATTGAGGCCA	TCAGTGACCGTCGGCCGAGGCATCACCTCAGCCAAACGAC
AGCCCGGCCGGCGCTTGAGGCCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_008410620.1|2616559_2617207_+|hypothetical-protein	unknown	unknown	gnl|CDD|370723
NZ_CP047147.1|WP_008410614.1|2618842_2619499_-|phosphoribosylglycinamide-formyltransferase	unknown	unknown	gnl|CDD|235544
NZ_CP047147.1|WP_159312364.1|2622612_2623830_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|132028
NZ_CP047147.1|WP_159312363.1|2620737_2622432_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_003948505.1|2623934_2624819_-|succinate--CoA-ligase-subunit-alpha	unknown	unknown	gnl|CDD|180194
NZ_CP047147.1|WP_003948498.1|2615390_2616254_-|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase	unknown	unknown	gnl|CDD|237637
NZ_CP047147.1|WP_159312360.1|2611962_2612775_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|366659
NZ_CP047147.1|WP_026235045.1|2606923_2607187_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159312357.1|2607259_2608048_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_003948506.1|2624839_2626018_-|ADP-forming-succinate--CoA-ligase-subunit-beta	unknown	unknown	gnl|CDD|234813
NZ_CP047147.1|WP_033237583.1|2604525_2606028_-|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|143437
NZ_CP047147.1|WP_129814764.1|2614834_2615368_-|DUF3017-domain-containing-protein	unknown	unknown	gnl|CDD|378602
NZ_CP047147.1|WP_121843217.1|2617283_2618846_-|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	unknown	unknown	gnl|CDD|234854
NZ_CP047147.1|WP_003948490.1|2606516_2606837_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_003948493.1|2608203_2609193_-|malate-dehydrogenase	unknown	unknown	gnl|CDD|235468
NZ_CP047147.1|WP_159312359.1|2611099_2611966_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379262
NZ_CP047147.1|WP_159312362.1|2619810_2620689_+|hypothetical-protein	unknown	unknown	gnl|CDD|366494
NZ_CP047147.1|WP_003948488.1|2602817_2604335_-|oxidoreductase	unknown	unknown	gnl|CDD|235000
NZ_CP047147.1|WP_129291649.1|2613691_2614657_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159312358.1|2609537_2610599_-|DUF2690-domain-containing-protein	unknown	unknown	gnl|CDD|371292

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_008410620.1|2616559_2617207_+|hypothetical-protein	gnl|CDD|370723	pfam09849, DUF2076, Uncharacterized protein conserved in bacteria (DUF2076). This domain, found in various hypothetical prokaryotic proteins, has no known function. The domain, however, is found in various periplasmic ligand-binding sensor proteins.	0.000337301
NZ_CP047147.1|WP_008410614.1|2618842_2619499_-|phosphoribosylglycinamide-formyltransferase	gnl|CDD|235544	PRK05647, purN, phosphoribosylglycinamide formyltransferase; Reviewed.	2.31986e-109
NZ_CP047147.1|WP_159312364.1|2622612_2623830_+|helix-turn-helix-domain-containing-protein	gnl|CDD|132028	TIGR02983, putative_RNA_polymerase_ECF-subfamily_sigma_factor, RNA polymerase sigma-70 factor, sigma-E family. This group of similar sigma-70 factors includes the sigE factor from Streptomyces coelicolor. The family appears to include a paralagous expansion in the Streptomycetes lineage, while related Actinomycetales have at most two representatives.	9.44226e-09
NZ_CP047147.1|WP_003948506.1|2624839_2626018_-|ADP-forming-succinate--CoA-ligase-subunit-beta	gnl|CDD|234813	PRK00696, sucC, ADP-forming succinate--CoA ligase subunit beta.	0
NZ_CP047147.1|WP_003948505.1|2623934_2624819_-|succinate--CoA-ligase-subunit-alpha	gnl|CDD|180194	PRK05678, PRK05678, succinyl-CoA synthetase subunit alpha; Validated.	0
NZ_CP047147.1|WP_003948498.1|2615390_2616254_-|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase	gnl|CDD|237637	PRK14193, PRK14193, bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional.	0
NZ_CP047147.1|WP_159312360.1|2611962_2612775_-|helix-turn-helix-domain-containing-protein	gnl|CDD|366659	pfam01471, PG_binding_1, Putative peptidoglycan binding domain. This domain is composed of three alpha helices. This domain is found at the N or C-terminus of a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. This family is found N-terminal to the catalytic domain of matrixins. The domain is found to bind peptidoglycan experimentally.	2.58334e-15
NZ_CP047147.1|WP_159312359.1|2611099_2611966_-|helix-turn-helix-domain-containing-protein	gnl|CDD|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	4.31357e-06
NZ_CP047147.1|WP_033237583.1|2604525_2606028_-|aldehyde-dehydrogenase-family-protein	gnl|CDD|143437	cd07119, ALDH_BADH-GbsA, Bacillus subtilis NAD+-dependent betaine aldehyde dehydrogenase-like. Included in this CD is the NAD+-dependent, betaine aldehyde dehydrogenase (BADH, GbsA, EC=1.2.1.8) of Bacillus subtilis involved in the synthesis of the osmoprotectant glycine betaine from choline or glycine betaine aldehyde.	0
NZ_CP047147.1|WP_129814764.1|2614834_2615368_-|DUF3017-domain-containing-protein	gnl|CDD|378602	pfam11222, DUF3017, Protein of unknown function (DUF3017). This bacterial family of proteins with unknown function appear to be restricted to Actinobacteria.	4.24581e-19
NZ_CP047147.1|WP_003948493.1|2608203_2609193_-|malate-dehydrogenase	gnl|CDD|235468	PRK05442, PRK05442, malate dehydrogenase; Provisional.	0
NZ_CP047147.1|WP_159312362.1|2619810_2620689_+|hypothetical-protein	gnl|CDD|366494	pfam01153, Glypican, Glypican.	0.00161531
NZ_CP047147.1|WP_003948488.1|2602817_2604335_-|oxidoreductase	gnl|CDD|235000	PRK02106, PRK02106, choline dehydrogenase; Validated.	1.80522e-119
NZ_CP047147.1|WP_121843217.1|2617283_2618846_-|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	gnl|CDD|234854	PRK00881, purH, bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional.	0
NZ_CP047147.1|WP_159312358.1|2609537_2610599_-|DUF2690-domain-containing-protein	gnl|CDD|371292	pfam10901, DUF2690, Protein of unknown function (DUF2690). This bacterial family of proteins has no known function.	1.67808e-16

Protein sequences

>NZ_CP047147.1|WP_129291649.1|2613691_2614657_+|hypothetical-protein
MAICTSLAEADVAALEELIRDTADPLRAFNAFYILLARHRRALDGGRFRTLYLRHAGRFSAVPMRAVLESDLALLDPMGPNLPAALRHAVTAVTAYPDNLALVAHHARVLAEYGWSGAETSEDEVREALTQVERAVEISPDQPRYRAVRAQLAALLNDFDTALASIQRALDLEDSSRAGYAVRIVEFHRIRADIVLRRETEQNRTTLRETAERLERSMEERVRRVAEETRAHEQKELTRLRSETLASLGLLAAVIAFIATGTQIAQDLPVREALRMLAGLAGMLTLVFTAFGAVFGIGRPTRLILPGLFGATLFLFAWATA
>NZ_CP047147.1|WP_159312360.1|2611962_2612775_-|helix-turn-helix-domain-containing-protein
MARWAELPAGLDRRERQLVVQLRRLKDHSGLSLSALGARTGYSRSSWERYLSGRAPVPRAAVIGLAEVCGVDPTRLLALHEVATEHRAADGHSTGTAQPLADTGPASRSWAGEHPEPPGPPAGRRRTAVAAALLVGAVALGFAVGLTTGLVAGSGTRAAAGPGRADAPDLVRPDGERWRRGAEHTCRVHRAEGLLHAGHSHERTAYLDINSSGWHVVEAQCLLRHHGVDPGAVDGLYGPVVQEAVRRFQAARRIPVDGVVGPDTWGELRR
>NZ_CP047147.1|WP_159312359.1|2611099_2611966_-|helix-turn-helix-domain-containing-protein
MTDDATPPECRRLLGELRSLRERSGHSLAALAAVTPYSKSSWGRYLSGAQPVPRAAVVALCQVAGERPARLLALWELADAEWSGRGSYTVQGRTGTPGAPAAPPETGITAEPVARPSRRRRSWWLLVAGAVLAVVAGAGAGVKALAERAPPAAASEPDAGPWRQDGPLVHGCTGPGCDGLAPGALGCDRADAVVTLAEHRTGEGRRVQVRYGRDCRALWARASGLRAGDRFALRLPGAPARTAGPVGEEEAAGYLATLMTGVSGPGVAAGATACLLPVHGPEECAPVR
>NZ_CP047147.1|WP_159312358.1|2609537_2610599_-|DUF2690-domain-containing-protein
MARWKPLPEELDPQVREFAGQLRRLVDRSGLSIAAVSDRTGYSKTSWERYLNGRLLAPKRAIIALAEATGTNPVHLTTMWELAERAWSRSEMRHDMTMEAIRITQARAALGDFTPPQGIDLGHRAPKAGARAKVNGADGPGGRGGAPAGVREAPPIPSVPRQPGPPGAAVPPGPPPGGDASGGSGKGGKGKRLPLILGGAVAALALVAGGLFLLAPGDEPAPQPTAKPTKTAKKLPAGVKCAGADCTGEDPEAMGCAGEQAVTSATATVGPTVVEIRYSKTCEAAWARITQAAAGDEIAIDVGTEAQESAKVATTFDAYTAMLAVENPADAKACATLAAGTTGCTTPSTTPTP
>NZ_CP047147.1|WP_003948493.1|2608203_2609193_-|malate-dehydrogenase
MTRTPVNVTVTGAAGQIGYALLFRIASGHLLGADVPVRLRLLEIPQGLKAAEGTAMELDDCAFPLLQGIEITDDPNVGFDGANVALLVGARPRTKGMERGDLLEANGGIFKPQGKAINDHAADDIKVLVVGNPANTNALIAQAAAPDVPAERFTAMTRLDHNRALSQLAKKTGAQVSDIKKLTIWGNHSATQYPDIFHAEIAGKNAAEVIADEQWLADDFIPTVAKRGAAIIEARGASSAASAANAAIDHVHTWVNGTAEGNWTSMGIPSDGSYGVPEGLISSFPVTTKNGTYEIVQGLDINEFSRARIDASVQELAEERDAVRALGLI
>NZ_CP047147.1|WP_159312357.1|2607259_2608048_+|hypothetical-protein
MPHPIRAAAAAAASTLLAATAALAAPGAASAAEDDLSRLSAEEIAERARTELRGAASLRVTLDQDQFDGGTGALEDPATADLAMDERGRCAGNVTLTRGRGSVELVKRGDEVWVKPDRDFWEAQLPGGQGTAAADTLHGRYVHGSTRDGVLAAVTEACDLDSLKEDLTGEATPDKGTRMTKGAATTAVFTPVIPLLRQEDGERVTLYVATEGPPRLVQATRTSDVKEDTVTVTGYGATVRAEPPAEKDTVDLSTLRDRLGPL
>NZ_CP047147.1|WP_026235045.1|2606923_2607187_+|hypothetical-protein
MLRNWRDLERTEELSPRQERWLRRMWWLYWSMLALSVGLVVLRVVEGDPPLQILFSALVVAVWIFNLYALRKRLRGHEAASAARQEG
>NZ_CP047147.1|WP_003948490.1|2606516_2606837_-|hypothetical-protein
MWGTPKNQTRLRFVQDSDEVLAALERTLADAPESERPGLRRALAVARAARLDEDTLRTRWLDARLASVAFTGDRDSVAAVRALRKAEPTLSLTEAVSLLRPPKPDA
>NZ_CP047147.1|WP_033237583.1|2604525_2606028_-|aldehyde-dehydrogenase-family-protein
MSAEQTIYVDGTWRAATSGAVREIIDPADAKPFAVVAEGGTEDADAAVAAARRAFDQGPWPHTPVAERAALLRRVADLLVRDREEIGLLESRDAGKTLEEGRVDVDCVADAFRYFADLVVGEGAGRVVDAGTDEVHSVVVHEPVGVCGLITPWNYPLLQASWKVAPALAAGNTFVLKPSEITPLSTIALMRLLAEAGLPEGVANLVTGPGHTVGARFGTHDDVDLVSFTGGLVSGTKVAQAAAASVKKVALELGGKNPNVVFADACATDEDFDTAVDQALNAAFIHSGQVCSAGSRLIVEESVRERFVTELTRRAQLIRLGRGTEEGVECGPLVSQAQLEKTQGFVASALEEGAVLRTGGKQPEPSEVRPATGYFYEPTVLDGCHREMRVVREEVFGPVLTVETFTTEDEAVALANDTEYGLAGAVWTTDAGRARRVAARLRHGTVWINDFHPYLPQAEWGGFGKSGTGRELGPAGLAEYRESKHVYQNLAPKPVRWFAG
>NZ_CP047147.1|WP_003948488.1|2602817_2604335_-|oxidoreductase
MPTYDYVVIGGGTAGSVIASRLTENPDTTVAIIEGGPSDIDRPDVLTLRRWMGLLGGDLDYDYPTTEQPRGNSHIRHSRAKVLGGCSSHNTLIAFKPLPSDWDEWETAGAEGWGAVPMEAYYARLKNNIVPVDEKDRNAIARDFVDAAQGALGVPHVDGFNQKPFSEGVGFFDLAYHPENNKRSSASVAYLHPYLDRPNLHLMLETWAYQLAFDGDRATGVHVRTKDGEEILVEAGREVLLCAGAVDSPRLLLHSGIGPRADLEKLGITVRHDLPGVGENLLDHPESVIVWETDGPIPENSAMDSDAGLFVRRDPKGRGPDLMFHFYQIPFTDNPERLGYERPAHGVSMTPNIPKPHSRGRLYLTSADPEVKPALDFRYFTDEDDYDAQTLVDGIKIARRIARTEPLAGWLKREVAPGPGITDDEALSEYARKVAHTVYHPAGTCRMGAEDDELAVVTPELKIRGLTNIRIADASVFPTMPAVNPMIGVLMVGEKCAEMLGGDAR
>NZ_CP047147.1|WP_129814764.1|2614834_2615368_-|DUF3017-domain-containing-protein
MSTDAPDDRPTAEQTPMAPEPRPEPAGGASRAGAGVRTGVAKLGWTRREPGSRRFPRITRSIARPEGGGRAAAGDAPAPARQWPMLLVLSLVGLGLILTAFDVTRVGTLLIGVALLVGAGLRWWLPSVGMLAVRSRFTDLVTYSVLGVVIVVLALMQQPSPWLELPFLDRTLHFTVD
>NZ_CP047147.1|WP_003948498.1|2615390_2616254_-|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase
MSAQILDGKATAAAIKSELAQRVAALRAQGVLPGLGTVLVGEDPGSQKYVAGKHRDCAQVGIASIQRELPATATQEEIEAVVRELNEDPACTGYIVQLPLPKGIDENRILELMDPAKDADGLHPTNLGRLVLNEPAPLPCTPFGIVTLLRHFGVEINGAEVVVVGRGVTIGRPMPLLLTRRSENATVTQCHTGTRDLAAHLRRADIIVAAAGVPHLVKPEDVKPGAAVLDVGVSRDENGKIVGDVHPGVAEVAGWISPNPGGVGPMTRAQLLVNVVEAAERQAASAA
>NZ_CP047147.1|WP_008410620.1|2616559_2617207_+|hypothetical-protein
MSFGDPNNPYGPPQGQPGGYGSPQGQPGGYGAPQGQPAYGYPQQGGQPGQPGYGYPQQGGQPGYPGGPGMNPMKPEMPGLMKTARVLLFIVAGLQILVGLLFGVAIGAAKDVANGMDTDAANGLVGLGYVLVFLLLALAVLAIVLGVKFSTGGSGIRITTIVYASLMLLGSLSNLFAGEGGSATFGGIVALAIYGIILAAMVNSQASVWFNRPRY
>NZ_CP047147.1|WP_121843217.1|2617283_2618846_-|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase
MTAEGTKRPIRRALVSVYDKTGLEELARGLHEAGVELVSTGSTAGRIAAAGVPVTKVEELTGFPECLDGRVKTLHPRVHAGILADLRLDSHREQLAELGVEPFQLVIVNLYPFRETVASGATPDECVEQIDIGGPSMVRAAAKNHPSVAVVTDPGQYGAVLEAARDGGFELSARKRLAAKAFQHTAAYDVAVASWFADDYAAADDSGFPDFLGSALTRSTVLRYGENPHQPAALYTLGEGGLAEAEQLHGKEMSYNNYTDTDAARRAAYDHADPCVAIIKHANPCGIAVAGDVAEAHRKAHACDPLSAFGGVIAVNRPVTREMAEQVAEIFTEVIVAPDYEDGALEALTRKKNIRVLRCPEPPAATVETKQIDGGALLQEADRLQAGGDSPANWTLATGDALGEGELAELAFAWRACRAVKSNAILLAKDGASVGVGMGQVNRVDSAKLAVERAGEERARGAFAASDAFFPFPDGLEILLEAGVRAVVQPGGSVRDELVVEAAKKAGVTMYFTGTRHFFH
>NZ_CP047147.1|WP_008410614.1|2618842_2619499_-|phosphoribosylglycinamide-formyltransferase
MASPLPSAASSRPKRLVVLVSGSGTNLQALLDAIAAQGAGAYGAEVVAVGADRGAIAGLDRAERAGIPSFVCRVKDHPDRAAWDRALTEAVAAYEPDLVVSAGFMKILGKEFLARFGGRVVNTHPALLPSFPGAHGVRDALAYGVKVTGCTVHLVDDGVDTGPIIAQGVVEVVEDDSAEGEAALHERIKDVERTLLVEVVGRLARNGHRIEGRKVLIP
>NZ_CP047147.1|WP_159312362.1|2619810_2620689_+|hypothetical-protein
MPDRRSAVSLRLPLPTAAPGFGGLALPGAAATAPDAWGVVAVRESSEKERKSSSEPEGRSGSDSGSGSDSGSGQSDNPFAAPPEGRPDQPWKPRTPAGGSDDGSGQGGGGGRWSDRQPGRSPNPFGSGSRDGSGEGRPPGPRWDPRDPGQRRARYALLSGMWSFFFALFNWPSVALLLGALSVYWGVTSLKMRGKPAEGADGEAREKRGPGESAPASTESGTRQQTTAAVSGLVTAGLGLALVAAMFGARIVYSDYYSCMDDALTNATRDTCEKHLPKDLRPLLGVNTENNG
>NZ_CP047147.1|WP_159312363.1|2620737_2622432_-|hypothetical-protein
MTDDSLSPAARLQALADRLRDRSPALAGCLFGGAVAAGLGLGAYAVVVMALWIGSPYPDSGPGGATGTAVSLWLLGHGVGLTRADTLTGVPAPLGLTPLLLALLPFWLVRRAARDAAEPETPQAPEIPARTVVWGVTGGYTAVGALAALYATGGELRPTLREAAWHLPLLALAAALTGLRSVRGRGADAPSPAGPDGGSGGVRAALAGRRGATACRAGLAAALTLAGGGAVLVGVSLTLHWDPARASYLMLTDVWSGRLAVLLLALALLPNAVIWGAAYALGTGFQVGTGTLVTPLAATSGPALPPFPLLAAVPPDGSGTPLTWACAVIPVVAGITAGWFTGRAAAPDRSSGTDAEGAPPPWSAPVTAATAALAALVAGLVCAVAARAAGGPLGTGRLAELGPVWWAAGGAALAWTLLLGVPTALALRAWRLRTRKPREAGSGGGRWAGAGLFGIAMTGTGLAVPGAADGGTDPEARPGADADADADIEEEADEPDDDPERVDPLDWWERVSRPDPVAALGGSFGTPYDLYDQLPAHGPEDWRALPAEEPAPPGERPAGREPDA
>NZ_CP047147.1|WP_159312364.1|2622612_2623830_+|helix-turn-helix-domain-containing-protein
MTNRPAPTLPTPAERRRLREAASLSQAALAARMSVTSTTIHSWETGRATPRGRALEAYASFLTTTARRPGPAGKPVRTSRSQAGTAVKGGEDKARGEVGEKAGAPPEPARAEASRPRPARPEPPRPSPRPPRPTGATPREAFDALYASCAGVLVRQTYLLTGRHTVAVESVERAFQLAWARWPEVAVDRDPAGWVRAAAHEYALSPWHRMRAAHRRPATPGAVLPPPRGRADHDLMDALLSLAPRHRRTLLLYDGVGLDLPETAAETEATTRAAAHRVLSARAAVAERVPALADPVALHRRLDALSRLEPATEEQGALIRTGGERRVRRWTRSAVVLTAVIAGATAFCVSVAPDHYVRPPAAGEAITGVPPHAGPGPLSEEDRSLREKLREHPAAGPERVRPLPR
>NZ_CP047147.1|WP_003948505.1|2623934_2624819_-|succinate--CoA-ligase-subunit-alpha
MAIFLTKDSKVIVQGMTGATGMKHTKLMLGDGTNIVGGVNPRKAGTSVDFDGTEVPVFGSVAEAIEKTGADVSVIFVPPKFAKAAVVEAIDAEIGLAVVITEGIAVHDSAAFWAYASSKGNKTRIIGPNCPGLITPGQSNAGIIPGDITKPGRIGLVSKSGTLTYQMMYELRDIGFSSAVGIGGDPVIGTTHIDALAAFEADPETDLIVMIGEIGGDAEERAADYIKANVTKPVVGYVAGFTAPEGKTMGHAGAIVSGSSGTAQAKKEALEAAGVKVGKTPTETAELARAILAG
>NZ_CP047147.1|WP_003948506.1|2624839_2626018_-|ADP-forming-succinate--CoA-ligase-subunit-beta
MDLFEYQARDLFAKHGVPVLAGEVIDTPEAAREATERLGGKSVVKAQVKVGGRGKAGGVKLAATPDEAVARATDILGMDIKGHTVHKVMIAETAPEIVEEYYVSYLLDRTNRTFLAMASVQGGMDIEEVAEKTPEALAKVPVDSNTGVTIEKAREIVAQAKFPAEVAEKVAEVMVTLWDTFVAEDALLVEVNPLAKVASGEVLALDGKVSLDENADFRQPDHEALEDKAAANPLEAAAKAKNLNYVKLDGEVGIIGNGAGLVMSTLDVVAYAGEKHGNVKPANFLDIGGGASAEVMANGLEIILGDPDVKSVFVNVFGGITACDEVANGIVQALELLKTKGEDVTKPLVVRLDGNNAELGRKILSDANHPLVQRVDTMDGAADKAAELAAAK

Crispr_ID: NZ_CP047147_9

• CRISPR_ID: NZ_CP047147_9
• CRISPR_location: 2703715-2703892
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP047147_9

Consensus_repeat	Method
GCCAAACCCAGCCCGGCCGGCGCTTGAGGCCACCC	PILER-CR
CAGCCCGGCCGGCGCTTGAGGCCA	CRISPRCasFinder

spacers of NZ_CP047147_9

>9.1|2703750|52|NZ_CP047147|PILER-CR
CACCGCAGCCCCTTGCGGGCTGACACGTACGCCCGAAGCCTCGGCCACCACT
>9.2|2703837|30|NZ_CP047147|PILER-CR
TCGGTGACCGGCACGGTCAGACGTGTCCGC
>9.3|2703747|57|NZ_CP047147|CRISPRCasFinder
CCCCACCGCAGCCCCTTGCGGGCTGACACGTACGCCCGAAGCCTCGGCCACCACTCC
>9.4|2703828|38|NZ_CP047147|CRISPRCasFinder
TCGGTGACCGGCACGGTCAGACGTGTCCGCGCCAAAAC

CRISPR arrays and Neighbor proteins around NZ_CP047147_9

CRISPR arrays

The CRISPR arrays of NZ_CP047147_9

>merge|NZ_CP047147|9|2703715-2703892|PILER-CR,CRISPRCasFinder
GCCAACCTCAGCCCGGCCGGCGCTTGAGGCCACCCCACCGCAGCCCCTTGCGGGCTGACACGTACGCCCGAAGCCTCGGCCACCACTCCCAGCCCGGCCGGCGCTTGAGGCCATCGGTGACCGGCACGGTCAGACGTGTCCGCGCCAAAACCAGCCCGGCCGGCGCTTGAGGCCACCC

>NZ_CP047147|9|2|2703715-2703892|PILER-CR
GCCAACCTCAGCCCGGCCGGCGCTTGAGGCCACCC	CACCGCAGCCCCTTGCGGGCTGACACGTACGCCCGAAGCCTCGGCCACCACT
CCCAGCCCGGCCGGCGCTTGAGGCCATCGGTGACC	GGCACGGTCAGACGTGTCCGCGCCAAAACC
AGCCCGGCCGGCGCTTGAGGCCACCC

>NZ_CP047147|9|8|2703723-2703889|CRISPRCasFinder
CAGCCCGGCCGGCGCTTGAGGCCA	CCCCACCGCAGCCCCTTGCGGGCTGACACGTACGCCCGAAGCCTCGGCCACCACTCC
CAGCCCGGCCGGCGCTTGAGGCCA	TCGGTGACCGGCACGGTCAGACGTGTCCGCGCCAAAAC
CAGCCCGGCCGGCGCTTGAGGCCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_010638764.1|2711661_2712324_-|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-dimerization-subunit-type-1-TsaB	unknown	unknown	gnl|CDD|274750
NZ_CP047147.1|WP_003948578.1|2708471_2708951_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_008414818.1|2709694_2709970_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_003948569.1|2698853_2699198_+|WhiB-family-transcriptional-regulator	unknown	unknown	gnl|CDD|376791
NZ_CP047147.1|WP_159312394.1|2705112_2706321_+|SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|380115
NZ_CP047147.1|WP_003948566.1|2695298_2696807_-|IMP-dehydrogenase	unknown	unknown	gnl|CDD|376340
NZ_CP047147.1|WP_129810846.1|2704071_2705010_-|polysaccharide-deacetylase-family-protein	unknown	unknown	gnl|CDD|213022
NZ_CP047147.1|WP_003948570.1|2699371_2700268_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176115
NZ_CP047147.1|WP_086014567.1|2711095_2711617_-|ribosomal-protein-S18-alanine-N-acetyltransferase	unknown	unknown	gnl|CDD|273701
NZ_CP047147.1|WP_159312396.1|2707070_2708441_+|MFS-transporter	unknown	unknown	gnl|CDD|340883
NZ_CP047147.1|WP_003948579.1|2709060_2709477_-|CBS-domain-containing-protein	unknown	unknown	gnl|CDD|341390
NZ_CP047147.1|WP_003948573.1|2703091_2703400_-|co-chaperone-GroES	unknown	unknown	gnl|CDD|178988
NZ_CP047147.1|WP_003948581.1|2709966_2711103_-|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-transferase-subunit-TsaD	unknown	unknown	gnl|CDD|236585
NZ_CP047147.1|WP_008413971.1|2700407_2701220_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|223377
NZ_CP047147.1|WP_159312395.1|2706426_2707074_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|378968
NZ_CP047147.1|WP_003948572.1|2701311_2702934_-|chaperonin-GroEL	unknown	unknown	gnl|CDD|234573
NZ_CP047147.1|WP_003948564.1|2692712_2693978_+|nucleotide-sugar-dehydrogenase	unknown	unknown	gnl|CDD|223749
NZ_CP047147.1|WP_003948568.1|2697796_2698408_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NZ_CP047147.1|WP_003948565.1|2694068_2695196_-|GuaB3-family-IMP-dehydrogenase-related-protein	unknown	unknown	gnl|CDD|236322
NZ_CP047147.1|WP_003948567.1|2696968_2697544_-|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|236607

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_010638764.1|2711661_2712324_-|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-dimerization-subunit-type-1-TsaB	gnl|CDD|274750	TIGR03725, T6A_YeaZ, tRNA threonylcarbamoyl adenosine modification protein YeaZ. This family describes a protein family, YeaZ, now associated with the threonylcarbamoyl adenosine (t6A) tRNA modification. Members of this family may occur as fusions with ygjD (previously gcp) or the ribosomal protein N-acetyltransferase rimI, and is frequently encoded next to rimI. [Protein synthesis, tRNA and rRNA base modification].	2.18837e-64
NZ_CP047147.1|WP_086014567.1|2711095_2711617_-|ribosomal-protein-S18-alanine-N-acetyltransferase	gnl|CDD|273701	TIGR01575, rimI, ribosomal-protein-alanine acetyltransferase. Members of this model belong to the GCN5-related N-acetyltransferase (GNAT) superfamily. This model covers prokarotes and the archaea. The seed contains a characterized accession for Gram negative E. coli. An untraceable characterized accession (PIR|S66013) for Gram positive B. subtilis scores well (205.0) in the full alignment. Characterized members are lacking in the archaea. Noise cutoff (72.4) was set to exclude M. loti paralog of rimI. Trusted cutoff (80.0) was set at next highest scoring member in the mini-database. [Protein synthesis, Ribosomal proteins: synthesis and modification].	2.36806e-31
NZ_CP047147.1|WP_003948569.1|2698853_2699198_+|WhiB-family-transcriptional-regulator	gnl|CDD|376791	pfam02467, Whib, Transcription factor WhiB. WhiB is a putative transcription factor in Actinobacteria, required for differentiation and sporulation.	1.22052e-27
NZ_CP047147.1|WP_159312394.1|2705112_2706321_+|SAM-dependent-methyltransferase	gnl|CDD|380115	pfam18096, Thump_like, THUMP domain-like. This is a domain of unknown function found in bacteria.	1.33885e-18
NZ_CP047147.1|WP_003948566.1|2695298_2696807_-|IMP-dehydrogenase	gnl|CDD|376340	pfam00478, IMPDH, IMP dehydrogenase / GMP reductase domain. This family is involved in biosynthesis of guanosine nucleotide. Members of this family contain a TIM barrel structure. In the inosine monophosphate dehydrogenases 2 CBS domains pfam00571 are inserted in the TIM barrel. This family is a member of the common phosphate binding site TIM barrel family.	0
NZ_CP047147.1|WP_129810846.1|2704071_2705010_-|polysaccharide-deacetylase-family-protein	gnl|CDD|213022	cd10917, CE4_NodB_like_6s_7s, Catalytic NodB homology domain of rhizobial NodB-like proteins. This family belongs to the large and functionally diverse carbohydrate esterase 4 (CE4) superfamily, whose members show strong sequence similarity with some variability due to their distinct carbohydrate substrates. It includes many rhizobial NodB chitooligosaccharide N-deacetylase (EC 3.5.1.-)-like proteins, mainly from bacteria and eukaryotes, such as chitin deacetylases (EC 3.5.1.41), bacterial peptidoglycan N-acetylglucosamine deacetylases (EC 3.5.1.-), and acetylxylan esterases (EC 3.1.1.72), which catalyze the N- or O-deacetylation of substrates such as acetylated chitin, peptidoglycan, and acetylated xylan. All members of this family contain a catalytic NodB homology domain with the same overall topology and a deformed (beta/alpha)8 barrel fold with 6- or 7 strands. Their catalytic activity is dependent on the presence of a divalent cation, preferably cobalt or zinc, and they employ a conserved His-His-Asp zinc-binding triad closely associated with the conserved catalytic base (aspartic acid) and acid (histidine) to carry out acid/base catalysis. Several family members show diversity both in metal ion specificities and in the residues that coordinate the metal.	2.49441e-35
NZ_CP047147.1|WP_003948570.1|2699371_2700268_-|LysR-family-transcriptional-regulator	gnl|CDD|176115	cd08423, PBP2_LTTR_like_6, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.41333e-56
NZ_CP047147.1|WP_159312396.1|2707070_2708441_+|MFS-transporter	gnl|CDD|340883	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters. This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.13086e-12
NZ_CP047147.1|WP_003948579.1|2709060_2709477_-|CBS-domain-containing-protein	gnl|CDD|341390	cd04622, CBS_pair_HRP1_like, CBS pair domain found in Hypoxic Response Protein 1 (HRP1) -like proteinds. Mycobacterium tuberculosis adapts to cellular stresses by upregulation of the dormancy survival regulon. Hypoxic response protein 1 (HRP1) is encoded by one of the most strongly upregulated genes in the dormancy survival regulon. HRP1 is a 'CBS-domain-only protein; however unlike other CBS containing proteins it does not appear to bind AMP. The biological function of the protein remains unclear, but is thought to contribute to the modulation of the host immune response. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).	1.22068e-35
NZ_CP047147.1|WP_003948573.1|2703091_2703400_-|co-chaperone-GroES	gnl|CDD|178988	PRK00364, groES, co-chaperonin GroES; Reviewed.	3.64761e-49
NZ_CP047147.1|WP_003948581.1|2709966_2711103_-|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-transferase-subunit-TsaD	gnl|CDD|236585	PRK09604, PRK09604, tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD.	6.79181e-179
NZ_CP047147.1|WP_008413971.1|2700407_2701220_+|SDR-family-oxidoreductase	gnl|CDD|223377	COG0300, DltE, Short-chain dehydrogenases of various substrate specificities [General function prediction only].	4.28598e-81
NZ_CP047147.1|WP_159312395.1|2706426_2707074_+|helix-turn-helix-domain-containing-protein	gnl|CDD|378968	pfam12840, HTH_20, Helix-turn-helix domain. This domain represents a DNA-binding Helix-turn-helix domain found in transcriptional regulatory proteins.	4.81579e-10
NZ_CP047147.1|WP_003948572.1|2701311_2702934_-|chaperonin-GroEL	gnl|CDD|234573	PRK00013, groEL, chaperonin GroEL; Reviewed.	0
NZ_CP047147.1|WP_003948564.1|2692712_2693978_+|nucleotide-sugar-dehydrogenase	gnl|CDD|223749	COG0677, WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell envelope biogenesis, outer membrane].	1.59681e-121
NZ_CP047147.1|WP_003948568.1|2697796_2698408_-|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.73082e-50
NZ_CP047147.1|WP_003948565.1|2694068_2695196_-|GuaB3-family-IMP-dehydrogenase-related-protein	gnl|CDD|236322	PRK08649, PRK08649, GuaB3 family IMP dehydrogenase-related protein.	0
NZ_CP047147.1|WP_003948567.1|2696968_2697544_-|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|236607	PRK09648, PRK09648, RNA polymerase sigma factor ShbA.	2.14712e-89

Protein sequences

>NZ_CP047147.1|WP_003948573.1|2703091_2703400_-|co-chaperone-GroES
MTTASSKVAIKPLEDRIVVQPLDAEQTTASGLVIPDTAKEKPQEGVVLAVGPGRFENGERLPLDVKTGDVVLYSKYGGTEVKYNGEEYLVLSARDVLAIIEK
>NZ_CP047147.1|WP_003948572.1|2701311_2702934_-|chaperonin-GroEL
MAKILKFDEDARRALERGVNQLADTVKVTIGPKGRNVVIDKKFGAPTITNDGVTIAREVECDDPYENLGAQLVKEVATKTNDIAGDGTTTATVLAQALVREGLRNVAAGASPAALKKGIDAAVAAVSAELLDTARPIDDKSDIAAVAALSAQDKQVGELIAEAMDKVGKDGVITVEESNTFGVDLDFTEGMAFDKGYLSPYMVTDQERMEAVLDDPYILIHQGKIGSIQDLLPLLEKVIQAGGSKPLLIIAEDVEGEALSTLVVNKIRGTFNAVAVKAPGFGDRRKAMLGDMATLTGATVIAEEVGLKLDQAGLDVLGTARRVTVTKDDTTIVDGGGNAEDVQGRVAQIKAEIESTDSDWDREKLQERLAKLAGGVCVIRVGAATEVELKERKHRLEDAISATRAAVEEGIVSGGGSALVHAVKVLDDNLGRTGDEATGVAVVRRAAVEPLRWIAENAGLEGYVITTKVAELDKGQGFNAATGEYGDLVKAGVIDPVKVTRSALENAASIASLLLTTETLVVEKPAEEEPEAGHGHGHSH
>NZ_CP047147.1|WP_008413971.1|2700407_2701220_+|SDR-family-oxidoreductase
MTTALITGSTAGIGAAFARRLAASGTDGSGADRGHGAGHHLVLVARDRERLRRQATELHDRHGVEVEVLPADLSTDEGIGAVEARLADRTHPVDLLVNNAGFGNKGAYLEVPLADELKMLKVHCEAVLRLTTAATASMRERGRGGVVNVASVAAFVPRGTYGASKAWVVQFTQGAAHDLAGSGVRLMALCPGFVRTEFHQRAKMGTDNIPGWMWLDADKLVAAALADLARGRTVSIPDPRYKALMGLVKLTPRALLTGMTSRTGRKYGPQ
>NZ_CP047147.1|WP_003948570.1|2699371_2700268_-|LysR-family-transcriptional-regulator
MIEARHLRVLRAVAATGSFSAAARELGCTQPAVSQQMKALESSAGTPLLIRTGREMRLTQAGEALTRHAAGILAGLTAAEEEVAAIAGLRAGRVRLVSFPSGSSSLVPAALAALRAAHPGTRVSLEEAEPPRSAELLRAGDCDIALAFRYAGATAPDEWDDLVVRPLLADRLVGLVPEGHRLADAASAGIGELAADPWIAGCPRCRRQLVEVCETEGFTPRIDFATDDYPAVLGLVAAGLGVAVLPALALESLRPKGVRTIAVEPAVEREIVALTLPDLAQVPAVAATLDHLAATAGR
>NZ_CP047147.1|WP_003948569.1|2698853_2699198_+|WhiB-family-transcriptional-regulator
MADFSRLPGPNADLWDWQLLAACRGVDSSLFFHPEGERGAARSARETSAKEVCMRCPVRAECAAHALAVREPYGVWGGLTEDEREELMGRARTRLTPAGAAPAPGPTPPGPGFP
>NZ_CP047147.1|WP_003948568.1|2697796_2698408_-|response-regulator-transcription-factor
MTSVLVCDDSPLAREALRRAVATVPGVERVTTAANGEEVLRRWGADRSDLILMDVRMPGLGGVETVRRLLSADPGARIIMLTVAEDLDGVALAVAAGARGYLHKDASRAELRATVTQALADPTWRLAPRRLRSAEMGAAPTLTAREIQVLEGMSHGRSNAEIGRELFLSEDTVKTHARRLFKKLGASDRAHAVALGFRWGLVR
>NZ_CP047147.1|WP_003948567.1|2696968_2697544_-|sigma-70-family-RNA-polymerase-sigma-factor
MRDDETTAIGGLVHRAVEGDEQATHDLLAHVHPLALRYCRTRLSRLPGDARHFVEDLAQEVCVAVLLALPRYKDTGRPFEAFVFAIAGHKVADLQRAAMRHPGSTAVPSDEMPERPDDSLGPEERALLSSDAAWAKQLLANLPQNQRELLLLRIAVGLTAEETGQMLGMSPGAVRVAQHRALSRLRALAEQ
>NZ_CP047147.1|WP_003948566.1|2695298_2696807_-|IMP-dehydrogenase
MTANVDGVPEKFATLGLTYDDVLLLPGASDMAPDQIDTTSRLSKNVKVNVPLLSAAMDKVTESRMAIAMARQGGAGVLHRNLSIEDQANQVDLVKRSESGMVTDPITVHPDATLGEADAICAKFRISGVPVTDGSGRLLGIVTNRDMAFESDRTRQVREVMTPMPLVTGKVGISGVDAMELLRRHKIEKLPLVDDEGVLKGLITVKDFVKAEKYPNAAKDSEGRLLVGAAVGVAGDAFERAQALIGAGVDFIVVDTAHGHSRLVGDMVAKIKSNSSGVDVIGGNIATRDGAQMLIDSGADGVKVGVGPGSICTTRVVAGIGVPQVTAIYEASLAAQAAGVPVIGDGGLQYSGDIAKALVAGADTVMLGSLLAGCEESPGELLFINGKQFKSYRGMGSLGAMQTRGDRKSFSKDRYFQEGVASDEKLVPEGIEGQVPYRGPLAQVVHQLVGGLRQSMFYVGGATVPELQRNGRFVRITSAGLKESHPHDIQMTVEAPNYAAKR
>NZ_CP047147.1|WP_003948565.1|2694068_2695196_-|GuaB3-family-IMP-dehydrogenase-related-protein
MTEIEIGRGKRGRRAYAFDDIAVVPSRRTRDPKEVSIAWQIDAYRFELPFLAAPMDSIVSPETAIRVGEFGGLGVLNLEGLWTRYEDPQPLLDEIAEELDEERATRRLQEIYDAPIQEELIGRRIKEVRDAGVITAAALSPQRTAQFSKAVVDAGVDIFVIRGTTVSAEHVSGAAEPLNLKQFIYELDVPVIVGGCATYTAALHLMRTGAAGVLVGFGGGAAHTTRNVLGIQVPMATAVADVAAARRDYLDESGGRYVHVIADGGVGWSGDLPKAIACGADAVMMGSPLARATDAPGKGHHWGMEAVHEDVPRGKLVDLGMVGTTEEILTGPSRTPDGSMNMFGALRRSMATTGYSELKEFQRVEVTVADSHHKR
>NZ_CP047147.1|WP_003948564.1|2692712_2693978_+|nucleotide-sugar-dehydrogenase
MPADLAVIGLGSHGLPLAQAAVGAGVDTIGYDPDRARDLASGRLPGTGAEGALTAADVRRMLSGGFRPTADPRELGRVRTAVICAPAPAGPSGGVDLGPLAEAARALAARLRPHTTVILESPAGPGTTEEFLRPLLESGSGLTAGRDFHLAYSPGRTDPGNRTHGYAATPKVIGGLTPACTESAAAFYGRLTDKVVRARGPREAETVHVLETNYRHVNLALVNEMAVLCHDLGVDLWDVIRCAETKPFGFQAFRPGPGAGGHGLPLDPSCLPHADATPGNGLRMVSLARDINARMPQYVIQRATQLLNEHGKSARAARVLLLGVTYKPDVADQQGAPAQEIALRLTERGASVSYHDPYVPHWSPAGRPVPRADSLYEAAAEADLTILLQNHRTYDLQGLAVKAQLLLDTRGTTPAGAAHRL
>NZ_CP047147.1|WP_129810846.1|2704071_2705010_-|polysaccharide-deacetylase-family-protein
MGQVRQNEQSGGRRLHPGGLLRRTRAARLVAAGLTAAALLSGCALGTDSGSGGPGTTGQAGPAPETKAQRLAKKQAAIAAATRRWGLAQVPLTAPAPPDAKPTLSTRDGFEVEGQENLPHVFTTVPVKERVVFLTIDDGAEKDPEFLRMMKELDIPYSAFLSDYLVSEDYDYFRAMQKQGTALHNHTLDHPYLPGLSYEEQRHQICGMQDIIEKQYGKRPRLFRPPYGNYNQDTLKAAKSCGIEAVPLWNAEAFIDRVDYREWDRDLHPGDIVLTHFRGTGQWDGTMVDMVRQAMKVITSKGYAVARLEDYI
>NZ_CP047147.1|WP_159312394.1|2705112_2706321_+|SAM-dependent-methyltransferase
MTDLDSFTALLTPEGRALLDAVAGHDPADELATATRLRRDHPAPLVSAALGQARLRQRAAVKFGADAARMFFTPHGVEQATRTEVAAHRAARIAALGVRSVADLCCGIGGDAVALARAGVRVLAVDRDPVTAAVARANAEALGLAELIEVREAEVAEVEVGGYDAVFVDPARRSGRGGRVFDPEAYSPPLSWAVEAALRAPVAALKIAPGVPHEAIPPQAEAEWISYGGDVKEAVLWFGGAGAPGGVRPVPGSVRATLLPAGDQLWSPEPPPDVPAGPVGRYLYEPDGAVIRAHQVAEVAERVGGHLVDETIAYVTSDSLRPTPFAAAYEITDVLPFNLKRLKALLREREVGVLTVKKRGSAVEPEEVRRRMKLRGPNAATVFLTRVAGAPTMLVGGPASAA
>NZ_CP047147.1|WP_159312395.1|2706426_2707074_+|helix-turn-helix-domain-containing-protein
MPEQPSSRIDLTHNPAALKALTHPLRVRLLGLLRSEGPATASELAATTGETSASTSYHLRVLARHGFVSEAMARDARERRWQAAHTLTTWDNEALLDQPGAEVFLATTRRQQVDHLGRTLDRHEADLAAGRLDPAWRAAAHLDDYEVRLTPASAAELGREFAARAAELAARDAGNPESARVVVVTAALPVTDRPARDAEAPEAPDAGPAHDGETP
>NZ_CP047147.1|WP_159312396.1|2707070_2708441_+|MFS-transporter
MTAAPAPADAHILDPETARRRYVTVSALFWFPIGLYVPSLVLILGERGLALAAVAAVLSSQGLTVALLELPTGGLSDVLGRRAVLAAGGVLSFAGLLLLALGTVPWVLITGIVLMGASRALASGPAEAWYVDMAQAHSGPEAELRTGLSRGSSAMGASLAVATLLGGLLPWLFAGSGLAAATGGLILPLSLPGLLSAALVLCYLAYVLLRLPEPPRAPSTLRSVLGSVPGTIASGVRLATRERVVRKVVLTTAAVGAALGAIELLTPGRAAAITGASESGAVVYAGLATAGFASSSLGARLAPLLARLAGGSGRAVLTALGGMACGLALLGLSAPGAGESASTPAVVTGVLGYVLVYLCLGAAGPNENDLLHHRVASSARATALSVQSLALQAVASLGGLVAGLLPLGPLPLLLTAAVVGAGALMWVRAVPDGPRPGHPDGADALAAPAASGEPGR
>NZ_CP047147.1|WP_003948578.1|2708471_2708951_+|hypothetical-protein
MSDSEDFDAFGDDVYQPQGEDTTDDSGIFDEEDNLMNTGLDDLRDEGYSPPEKPRAVEHTGTTAEEEREGESLDERLTEEVPDVQVPPGDGLGDTLDTDGELIDDEVGDLRAGRLVAPDEGAHEDAEKDIIAEDVGIDGAAASAEEAAVHLVDEDADDL
>NZ_CP047147.1|WP_003948579.1|2709060_2709477_-|CBS-domain-containing-protein
MADARTLMSTDVQSILAEETIDRAAQVMRDHNVGALPVKSADGALLGIVTDRDLVVRALAAGKTPDRTTLEDLVEDTPVAVTPDAHSTEVLQAMGNAQVRRVVVVEDGDLLGIISEADLAQHLADEDLAAFVRRVYQG
>NZ_CP047147.1|WP_008414818.1|2709694_2709970_-|hypothetical-protein
MTAHTLMWEARATQGRGADLLEWTRTRAAELAEATPSPLRTELFQAPQDRVLCLTWWHPDHGPDLPELPEPPAELITRAVHRWHFESVEVL
>NZ_CP047147.1|WP_003948581.1|2709966_2711103_-|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-transferase-subunit-TsaD
MADHRDEPLVLGIETSCDETGVGIVHGTTLLADAVASSVDEHARFGGVVPEVASRAHLEAMVATIERALTDAGVKARDLDGIAVTAGPGLAGALLVGVTAAKAYAYALGKPLYGVNHLASHICVDQLEHGRLPEPTMALLVSGGHSSLLLSSDITSDVRPLGATIDDAAGEAFDKIARVLQLGFPGGPVIDRLAREGDPEAIAFPRGLTGPRDAAYDFSFSGLKTAVARWIEAKRAAGEEIPVRDVAASFQEAVVDVLTRKAVRACKDEGVDHLMIGGGVAANSRLRALAEERCERAGIRLRVPRPGLCTDNGAMVAALGAEMVARNRAASDWQLSADSSLPVTETHVPGDAHLHPHPHSHAHSHDHVHETAKDNLYS
>NZ_CP047147.1|WP_086014567.1|2711095_2711617_-|ribosomal-protein-S18-alanine-N-acetyltransferase
MRWWDIDPVLALERELFPDDAWSRGMFWSELAHARGPEATHRYVAAYTGDRLVGYAGLATAGGTGDVQTIAVARDQWGSGLGSRLLTDLLEHATAFDCTEVMLEVRVDNTRAQALYARFGFEPIGFRRGYYQPGNVDALVMRLSDPSVNPAAPATPATDDPDSVPAQGTEHHG
>NZ_CP047147.1|WP_010638764.1|2711661_2712324_-|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-dimerization-subunit-type-1-TsaB
MLLLALDTATPAVTVALHDGERVLASDTQVDARRHGELLLPAVDKLLTGAGLALADVTGVVVGVGPGPYTGLRVGLMTADTFGFALGVPVHGVCTLDGLAYASDLGPDAGPFVVATDARRKEVYWGLYADSRTPLSGPAVDRPADLADRVAGLPAVGAGALLYPETFADARAPEHVSAAALASVAAERLAAGEELLPPRPLYLRRPDAQVPKNYKVVTPK

Crispr_ID: NZ_CP047147_10

• CRISPR_ID: NZ_CP047147_10
• CRISPR_location: 2741317-2741415
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP047147_10

Consensus_repeat	Method
AGCCCGTCCGGCGATTGAGGACA	CRISPRCasFinder

spacers of NZ_CP047147_10

>10.1|2741340|53|NZ_CP047147|CRISPRCasFinder
TCTTTTCAACCGGCCACGCACCCGAGGAATCCCCCGGAAGCCCGGCCAAACTC

CRISPR arrays and Neighbor proteins around NZ_CP047147_10

CRISPR arrays

The CRISPR arrays of NZ_CP047147_10

>merge|NZ_CP047147|10|2741317-2741415|CRISPRCasFinder
AGCCCGTCCGGCGATTGAGGACATCTTTTCAACCGGCCACGCACCCGAGGAATCCCCCGGAAGCCCGGCCAAACTCAGCCCGTCCGGCGCTTGAGGACA

>NZ_CP047147|10|9|2741317-2741415|CRISPRCasFinder
AGCCCGTCCGGCGATTGAGGACA	TCTTTTCAACCGGCCACGCACCCGAGGAATCCCCCGGAAGCCCGGCCAAACTC
AGCCCGTCCGGCGCTTGAGGACA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_003948618.1|2743150_2743531_-|30S-ribosomal-protein-S13	unknown	unknown	gnl|CDD|235358
NZ_CP047147.1|WP_008407256.1|2737443_2737947_-|30S-ribosomal-protein-S9	unknown	unknown	gnl|CDD|178888
NZ_CP047147.1|WP_003948615.1|2740609_2741110_-|50S-ribosomal-protein-L17	unknown	unknown	gnl|CDD|235522
NZ_CP047147.1|WP_003948622.1|2745381_2746038_-|adenylate-kinase	unknown	unknown	gnl|CDD|234711
NZ_CP047147.1|WP_003948621.1|2744399_2745236_-|type-I-methionyl-aminopeptidase	unknown	unknown	gnl|CDD|235576
NZ_CP047147.1|WP_003948624.1|2747585_2748041_-|50S-ribosomal-protein-L15	unknown	unknown	gnl|CDD|235523
NZ_CP047147.1|WP_003948619.1|2743752_2743866_-|50S-ribosomal-protein-L36	unknown	unknown	gnl|CDD|179039
NZ_CP047147.1|WP_033237646.1|2731684_2733586_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl|CDD|234729
NZ_CP047147.1|WP_003948616.1|2741496_2742519_-|DNA-directed-RNA-polymerase-subunit-alpha	unknown	unknown	gnl|CDD|235359
NZ_CP047147.1|WP_003948625.1|2748042_2748225_-|50S-ribosomal-protein-L30	unknown	unknown	gnl|CDD|180163
NZ_CP047147.1|WP_008407258.1|2735796_2737158_-|phosphoglucosamine-mutase	unknown	unknown	gnl|CDD|237672
NZ_CP047147.1|WP_003948612.1|2737990_2738434_-|50S-ribosomal-protein-L13	unknown	unknown	gnl|CDD|181703
NZ_CP047147.1|WP_003948617.1|2742680_2743085_-|30S-ribosomal-protein-S11	unknown	unknown	gnl|CDD|180007
NZ_CP047147.1|WP_003948609.1|2734738_2735716_+|type-I-pantothenate-kinase	unknown	unknown	gnl|CDD|235466
NZ_CP047147.1|WP_003948620.1|2743930_2744152_-|translation-initiation-factor-IF-1	unknown	unknown	gnl|CDD|178954
NZ_CP047147.1|WP_003948623.1|2746037_2747351_-|preprotein-translocase-subunit-SecY	unknown	unknown	gnl|CDD|236412
NZ_CP047147.1|WP_010638819.1|2738744_2739623_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_018468506.1|2734316_2734640_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159312401.1|2733730_2734291_-|MOSC-domain-containing-protein	unknown	unknown	gnl|CDD|225167
NZ_CP047147.1|WP_018894198.1|2739633_2740521_-|tRNA-pseudouridine(38-40)-synthase-TruA	unknown	unknown	gnl|CDD|234577

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_003948618.1|2743150_2743531_-|30S-ribosomal-protein-S13	gnl|CDD|235358	PRK05179, rpsM, 30S ribosomal protein S13; Validated.	4.74824e-76
NZ_CP047147.1|WP_003948612.1|2737990_2738434_-|50S-ribosomal-protein-L13	gnl|CDD|181703	PRK09216, rplM, 50S ribosomal protein L13; Reviewed.	1.07704e-101
NZ_CP047147.1|WP_003948615.1|2740609_2741110_-|50S-ribosomal-protein-L17	gnl|CDD|235522	PRK05591, rplQ, 50S ribosomal protein L17; Validated.	3.05388e-64
NZ_CP047147.1|WP_003948622.1|2745381_2746038_-|adenylate-kinase	gnl|CDD|234711	PRK00279, adk, adenylate kinase; Reviewed.	1.09724e-136
NZ_CP047147.1|WP_003948621.1|2744399_2745236_-|type-I-methionyl-aminopeptidase	gnl|CDD|235576	PRK05716, PRK05716, methionine aminopeptidase; Validated.	3.4816e-122
NZ_CP047147.1|WP_003948624.1|2747585_2748041_-|50S-ribosomal-protein-L15	gnl|CDD|235523	PRK05592, rplO, 50S ribosomal protein L15; Reviewed.	2.72449e-66
NZ_CP047147.1|WP_003948619.1|2743752_2743866_-|50S-ribosomal-protein-L36	gnl|CDD|179039	PRK00465, rpmJ, 50S ribosomal protein L36; Reviewed.	1.17108e-12
NZ_CP047147.1|WP_033237646.1|2731684_2733586_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl|CDD|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NZ_CP047147.1|WP_008407258.1|2735796_2737158_-|phosphoglucosamine-mutase	gnl|CDD|237672	PRK14318, glmM, phosphoglucosamine mutase; Provisional.	0
NZ_CP047147.1|WP_003948616.1|2741496_2742519_-|DNA-directed-RNA-polymerase-subunit-alpha	gnl|CDD|235359	PRK05182, PRK05182, DNA-directed RNA polymerase subunit alpha; Provisional.	0
NZ_CP047147.1|WP_003948625.1|2748042_2748225_-|50S-ribosomal-protein-L30	gnl|CDD|180163	PRK05611, rpmD, 50S ribosomal protein L30; Reviewed.	1.41718e-25
NZ_CP047147.1|WP_003948617.1|2742680_2743085_-|30S-ribosomal-protein-S11	gnl|CDD|180007	PRK05309, PRK05309, 30S ribosomal protein S11; Validated.	1.10697e-87
NZ_CP047147.1|WP_003948609.1|2734738_2735716_+|type-I-pantothenate-kinase	gnl|CDD|235466	PRK05439, PRK05439, pantothenate kinase; Provisional.	0
NZ_CP047147.1|WP_003948620.1|2743930_2744152_-|translation-initiation-factor-IF-1	gnl|CDD|178954	PRK00276, infA, translation initiation factor IF-1; Validated.	1.40523e-47
NZ_CP047147.1|WP_003948623.1|2746037_2747351_-|preprotein-translocase-subunit-SecY	gnl|CDD|236412	PRK09204, secY, preprotein translocase subunit SecY; Reviewed.	0
NZ_CP047147.1|WP_008407256.1|2737443_2737947_-|30S-ribosomal-protein-S9	gnl|CDD|178888	PRK00132, rpsI, 30S ribosomal protein S9; Reviewed.	1.29069e-75
NZ_CP047147.1|WP_159312401.1|2733730_2734291_-|MOSC-domain-containing-protein	gnl|CDD|225167	COG2258, COG2258, Uncharacterized protein conserved in bacteria [Function unknown].	7.98155e-23
NZ_CP047147.1|WP_018894198.1|2739633_2740521_-|tRNA-pseudouridine(38-40)-synthase-TruA	gnl|CDD|234577	PRK00021, truA, tRNA pseudouridine(38-40) synthase TruA.	2.6488e-105

Protein sequences

>NZ_CP047147.1|WP_003948615.1|2740609_2741110_-|50S-ribosomal-protein-L17
MPKPTKGARLGGSAAHERLMLANLARSLFEHGRIKTTEAKARRLRPYAERLVTKAKKGDLHNRRQVLQVITDKSVVHTLFTEIGPRYENRPGGYTRITKVGNRRGDNAPMAVIELVEALTVAQEATGEAEAATKRAVKEDAAGKDQAATEAPEAAAEAKDDEAKDA
>NZ_CP047147.1|WP_018894198.1|2739633_2740521_-|tRNA-pseudouridine(38-40)-synthase-TruA
MSEQVEYTERRDGPEDGHVRVRLDLSYDGRDFSGWAKQAAGRRTVQGEIEDALRTVTRSGERTYELTVAGRTDSGVHARGQVAHVDLPAAVWEEHREKLLRRLAGRLPHDVRIWRVAEAPAGFDARFSAVWRRYAYRVTDHPGGVDPLLRGHVLWHDWTLDVEAMNAASVALLGEHDFAAYCKRREGATTIRTLQELSWERDRDGIVTATVRADAFCHNMVRSLVGALLFVGDGHRPVEWPGKVLAAGVRDSAVHVVRPHGLTLEEVGYPADELLAARNREARNKRTLPNTACCG
>NZ_CP047147.1|WP_010638819.1|2738744_2739623_+|hypothetical-protein
MSYGQGGPPWGQGDRGPQGQQPYGQQRPATPDWEALASASEARGRKRRWTLIGGGAVATVAVAALVATLVVRANSDDPKASDPIGGVSSSSALPEDTTAPAPSFSEVAPPPPPDPKDFVSSAEKDKAPLTALSLYPGRKLTVGDRVYAKGALHRTTKCASGTQGALGQVLTKNGCEQLIRATYRRDGVAVTVGVATFKTADVAARVKEETSGNVASLAGEGVPTFCRTTVCRSTANAYGRYVYFTVGGFTNGDNVTKQDRAVFTTGDDVAEFTLRQIHRRGVAQASQAAAAQ
>NZ_CP047147.1|WP_003948612.1|2737990_2738434_-|50S-ribosomal-protein-L13
MRTYSPKPGDVTRQWHVIDARDVVLGRLATTAATLLRGKHKPIYAPHVDTGDFVVIINADKIHLSGNKRTQKMAYRHSGYPGGLRSVRYDELMDKNPEKAVEKAVKGMLPKNTLGRQMLSKLKVYAGEQHPHAAQQPVPFEITQVAQ
>NZ_CP047147.1|WP_008407256.1|2737443_2737947_-|30S-ribosomal-protein-S9
MAETTAELPLDDIEQYTTESETPEGDYTSESLASGFGEPQPAAGLGRRKNAIARVRIVPGTGKWKINGRTLEDYFPNKVHQQEVNEPFKVLELEGRYDVIARISGGGVSGQAGALRLGVARALNEADVDNNRGALKKAGFLTRDDRAVERKKAGLKKARKAPQYSKR
>NZ_CP047147.1|WP_008407258.1|2735796_2737158_-|phosphoglucosamine-mutase
MGRLFGTDGVRGVANADLTAELALGLSVAAAHVLAEAGTASTGHRQVAVVGRDPRASGEFLEAAVVAGLASAGVDVLRVGVLPTPAVAYLTGALGADLGVMLSASHNAMPDNGIKFFARGGHKLADELEDRIEALYEEHRTGAAWERPTGAGVGRVRDYDEGFDQYVAHLIGVLPNRLDGLKIVLDEAHGAAARVSPEAFARAGAEVVTIGADPDGLNINDGCGSTHMELLRAAVVEHGAHLGIAHDGDADRCLAVDAEGREIDGDQILAVLALSMREHGGLRSQTVVATVMSNLGFKLALEREGISLVQTAVGDRYVLEEMKEHGYALGGEQSGHVIILDHATTGDGTLTGLMLAARVAETGRPLAELAGVMERLPQVLVNVPDVDRSRVTTSAELASAVAQAEQELGATGRVLLRPSGTEPLVRVMVEAADIEQAGAIAGRLADVVKSALG
>NZ_CP047147.1|WP_003948609.1|2734738_2735716_+|type-I-pantothenate-kinase
MITPESRSAHRKPEATPYVDLTREQWSALREKTPLPLTADEVEKLRGLGDVIDLDEVRDIYLPLSRLLNLYVGATDGLRSALNTFLGEKGEQSGTPFVIGVAGSVAVGKSTVARLLQALLARWPEHPRVELVTTDGFLLPMAELRARGLTARKGFPESYDRRALTRFVADIKAGKDQVTAPVYSHLVYDIVPDRRLTVNRPDILIVEGLNVLQPALPGKDGRTRVGLADHFDFSVYVDARPEDIERWYLNRFRKLRATAFQDPSSYFRRYTQVSEEEALDYARSTWRTINLPNLVENVAPTRGRANLVIRKGPDHKVRKLSLRKL
>NZ_CP047147.1|WP_018468506.1|2734316_2734640_-|hypothetical-protein
MSTGAVGGAYGAGGVFWFAVERAEAAPAGRRGPLAAWRRWRGGAQARRDRALLARSAVVAELARELPDEDFGEYLEDAVALYRDGSKPYAEEAEYLDLVADALDRVG
>NZ_CP047147.1|WP_159312401.1|2733730_2734291_-|MOSC-domain-containing-protein
MSVRDGATGRITAVSSDGTHRFSKPNRAGITLLAGLGVAGDAHAGVTVQHRSRVARDPSRPNLRQVHLLAGELLAELAAAGHPVAPGELGENVTTYGVDLLALPTGALLRLGPEAVVEVTGLRNPCLQLDAFQEGLLRRVVGRAPDGSVVRRAGIMGVVRTGGTLRPGDPVGVELPAGEHRPLEPV
>NZ_CP047147.1|WP_033237646.1|2731684_2733586_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYVGAQSALDVVLAGLRRLEYRGYDSAGVAVLAGDQVACVKKAGKLSQLEKALVDDPLPGSDATGDGHGGATGIGHTRWATHGGPTDTNAHPHLDASGRCAVVHNGIIENFAALREELAARGADVRSQTDSEVAAHLLAEEYAALEGTGQEGGPRLAGALRAVCRRLEGAFTLVALHADVPDVIVGARRNSPLVVGCGEGEAFLASDVSAFIDHTRTAMELGQDQVVEVHPDRAVVTGFDGSPADARTYRVDWDASAAEKDGYDSFMLKEIAEQPKAVADTLLGRLDPALGTLTLGAELGLDPAVLREAEKVVVIACGTAHHAGLVARLAVERWAQLPCEVELASEFRYRDPIVGPRTLVVAVSQSGETADTLMALRHAREQGATVLAVCNTNGSTIPRESDAVLYTHAGPEVAVASTKAFLTQLVACLLLALHLGEVRRGPSEELREAARALSRAPEDVAAVLATMEPVRELARGLAHKETVLFLGRHSGHPVALEGALKLKELAYFHAEGFAAGELKHGPIALIEPDLPVIVVVPSPVTAALLHGKIVSNIQEIRARGARTIVLAEEGDEAVAPYADHLVRLPAVPPLIQPLVAAVPLQVFACELATARGNDVDQPRNLAKSVTVE
>NZ_CP047147.1|WP_003948616.1|2741496_2742519_-|DNA-directed-RNA-polymerase-subunit-alpha
MLIAQRPSLTEEVVDEFRSRFVIEPLEPGFGYTLGNSLRRTLLSSIPGAAVTSIRIDGVLHEFTTVPGVKEDVTDLILNIKQLVVSSEHDEPVVMYLRKQGPGLVTAADIAPPAGVEVHNPDLVLATLNAKGKLEMELTVERGRGYVSAVQNKQAGQEIGRVPVDSIYSPVLKVTYKVEATRVEQRTDFDKLIVDVETKQAMRPRDAMASAGKTLVELFGLARELNVDAEGIDMGPSPTDAALAADLALPIEELELTVRSYNCLKREGIHSVGELVARSEADLLDIRNFGAKSIDEVKAKLAGMSLALKDSPPGFDPTAAADAFGADDDADAGFVETEQY
>NZ_CP047147.1|WP_003948617.1|2742680_2743085_-|30S-ribosomal-protein-S11
MPPKGRQGAAKKVRRKEKKNVAHGHAHIKSTFNNTIVSITDPTGNVISWASAGHVGFKGSRKSTPFAAQMAAESAARRAQEHGMRKVDVFVKGPGSGRETAIRSLQATGLEVGSIQDVTPTPHNGCRPPKRRRV
>NZ_CP047147.1|WP_003948618.1|2743150_2743531_-|30S-ribosomal-protein-S13
MARVSGVDIPREKRVEVALTYVFGIGRTLSQQTLEATGVDPNARVRDLSEEDLVKIREYVDNNIKTEGDLRREIQADIRRKVEIGCYQGLRHRRGLPVHGQRTSTNARTRKGPRRAIAGKKKPGKK
>NZ_CP047147.1|WP_003948619.1|2743752_2743866_-|50S-ribosomal-protein-L36
MKVKPSVKKICDKCRVIRRHGRVMIICDNPRHKQRQG
>NZ_CP047147.1|WP_003948620.1|2743930_2744152_-|translation-initiation-factor-IF-1
MAKKQGAIEIEGTVVESLPNAMFKVELQNGHQVLAHISGKMRMHYIRILPDDRVVVELSPYDLTRGRIVYRYK
>NZ_CP047147.1|WP_003948621.1|2744399_2745236_-|type-I-methionyl-aminopeptidase
MVQIKSPEQIAKMREAGLVVAAIHRATREAAVPGATTQDLDQVARKVLEEHGARSNFLGYGGFPATICTSVNEVVVHGIPDEKTVLADGDIISIDCGAIVDGWHGDAAYTAFVGSGHAPELVELSRVTEESMWAGIAAMKQGNRLVDISRAIETYIRRQPKPGGGKYGIVEDYGGHGIGTEMHMDPHLLNYVERRRGKGPKLVPGFCLAIEPMVSLGTPKTEVLEDDWTVITTDGTWSSHWEHSVALTEQGPLVLTAEDGGKAKLAEFGITTAPDPAA
>NZ_CP047147.1|WP_003948622.1|2745381_2746038_-|adenylate-kinase
MRIVLVGPPGAGKGTQAAFLAKNLSIPHISTGDLFRANISQGTELGKQAKSYMDAGNLVPDEVTIGMAEDRMAQPDAENGFLLDGFPRNVSQAKALDESLKAQGVALDAVLDLEVPEDEVVKRIAGRRICRNDSSHVFHVEYSKPETEGVCDVCGGELYQRADDKEETVRKRLEVYHNETEPIIDHYKAQGLVVTISALGKVDEVTARAMAALGADQK
>NZ_CP047147.1|WP_003948623.1|2746037_2747351_-|preprotein-translocase-subunit-SecY
MLTAFARAFKTPDLRKKLLFTLGIIVLYRIGAHVPIPGVSYQNVQICMDQANATQGLFGLVNMFSGGALLQITIFALGIMPYITASIILQLLTVVIPRLEALKKEGSSGQAKITQYTRYLTVALAVLQGTGLVATARSGSLFQGCPVAGEIVPDQSIFVTAVMILTMTAGTALVMWLGELITDRGIGNGMSILMFISIAASFPASLWAIKEQGDLAGGWIEFGTVILVGLAMVGLVVFVEQAQRRIPVQYAKRMIGRRSYGGTSTYIPLKVNQAGVIPVIFASSLLYIPALIVQFSNSQAGWAQWINNNLADTGATAHVILYFFLIVFFAFFYVAISFNPEEVADNMKKYGGFIPGIRAGRPTAEYLSYVLNRITWPGSLYLGLIALVPTMALAGFGANQNFPFGGTSILIIVGVGLETVKQIESQLQQRNYEGFLR
>NZ_CP047147.1|WP_003948624.1|2747585_2748041_-|50S-ribosomal-protein-L15
MAEQNPLKVHNLRPAPGAKTAKTRVGRGEASKGKTAGRGTKGTKARYQVPERFEGGQMPLHMRLPKLKGFKNPFKTEFQVVNLDKLAELYPEGGEVTVEGLVAKGAVRKNSLVKVLGQGDVSVALQVTVDAVSGSAKEKITAAGGTVTELV
>NZ_CP047147.1|WP_003948625.1|2748042_2748225_-|50S-ribosomal-protein-L30
MPQLKITQKKSYIGSKQNHRDTLRSLGLKKVNDVVVKEDRPEFRGMVHTVRHLVTVEEVD

Crispr_ID: NZ_CP047147_11

• CRISPR_ID: NZ_CP047147_11
• CRISPR_location: 2858880-2858969
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP047147_11

Consensus_repeat	Method
TTGGCCTCAAGCGCCGGCCGGGCT	CRISPRCasFinder

spacers of NZ_CP047147_11

>11.1|2858904|42|NZ_CP047147|CRISPRCasFinder
GATTTTTCGGCTGGGCTCCGTCCCGACCGTGCCGGTCACCGA

CRISPR arrays and Neighbor proteins around NZ_CP047147_11

CRISPR arrays

The CRISPR arrays of NZ_CP047147_11

>merge|NZ_CP047147|11|2858880-2858969|CRISPRCasFinder
TTGGCCTCAAGCGCCGGCCGGGCTGATTTTTCGGCTGGGCTCCGTCCCGACCGTGCCGGTCACCGATTGGCCTCAAACGCCGGCCGGGCT

>NZ_CP047147|11|10|2858880-2858969|CRISPRCasFinder
TTGGCCTCAAGCGCCGGCCGGGCT	GATTTTTCGGCTGGGCTCCGTCCCGACCGTGCCGGTCACCGA
TTGGCCTCAAACGCCGGCCGGGCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_159312420.1|2860400_2861033_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_003948737.1|2854828_2855188_-|NADH-quinone-oxidoreductase-subunit-A	unknown	unknown	gnl|CDD|181171
NZ_CP047147.1|WP_159312422.1|2863080_2863809_-|prepilin-peptidase	unknown	unknown	gnl|CDD|224900
NZ_CP047147.1|WP_003948736.1|2854222_2854777_-|NADH-quinone-oxidoreductase-subunit-B	unknown	unknown	gnl|CDD|235797
NZ_CP047147.1|WP_003948741.1|2859637_2860333_-|demethylmenaquinone-methyltransferase	unknown	unknown	gnl|CDD|234689
NZ_CP047147.1|WP_031178386.1|2867901_2868363_-|membrane-protein	unknown	unknown	gnl|CDD|227296
NZ_CP047147.1|WP_008409043.1|2853470_2854226_-|NADH-quinone-oxidoreductase-subunit-C	unknown	unknown	gnl|CDD|181115
NZ_CP047147.1|WP_086014568.1|2868359_2868737_-|septum-determining-protein	unknown	unknown	gnl|CDD|377921
NZ_CP047147.1|WP_018468568.1|2847345_2849874_-|NADH-quinone-oxidoreductase-subunit-G	unknown	unknown	gnl|CDD|236118
NZ_CP047147.1|WP_018468576.1|2868838_2869216_-|pilus-assembly-protein	unknown	unknown	gnl|CDD|377921
NZ_CP047147.1|WP_008415886.1|2861047_2862247_-|dehypoxanthine-futalosine-cyclase	unknown	unknown	gnl|CDD|274731
NZ_CP047147.1|WP_030308501.1|2858333_2858840_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379112
NZ_CP047147.1|WP_030772685.1|2851219_2852056_-|NADH-quinone-oxidoreductase-subunit-NuoE	unknown	unknown	gnl|CDD|181024
NZ_CP047147.1|WP_018468570.1|2856058_2856847_+|C40-family-peptidase	unknown	unknown	gnl|CDD|366353
NZ_CP047147.1|WP_003948732.1|2849870_2851220_-|NADH-quinone-oxidoreductase-subunit-NuoF	unknown	unknown	gnl|CDD|131014
NZ_CP047147.1|WP_008415871.1|2869453_2869702_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_003948739.1|2856944_2858231_-|geranylgeranyl-reductase-family-protein	unknown	unknown	gnl|CDD|273936
NZ_CP047147.1|WP_008409042.1|2852091_2853471_-|NADH-quinone-oxidoreductase-subunit-D	unknown	unknown	gnl|CDD|180385
NZ_CP047147.1|WP_008415881.1|2863805_2866745_-|membrane-protein	unknown	unknown	gnl|CDD|198111
NZ_CP047147.1|WP_159312421.1|2862289_2862949_-|flavin-reductase-family-protein	unknown	unknown	gnl|CDD|224766

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_003948737.1|2854828_2855188_-|NADH-quinone-oxidoreductase-subunit-A	gnl|CDD|181171	PRK07928, PRK07928, NADH dehydrogenase subunit A; Validated.	4.73227e-78
NZ_CP047147.1|WP_159312422.1|2863080_2863809_-|prepilin-peptidase	gnl|CDD|224900	COG1989, PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion].	2.80302e-09
NZ_CP047147.1|WP_003948736.1|2854222_2854777_-|NADH-quinone-oxidoreductase-subunit-B	gnl|CDD|235797	PRK06411, PRK06411, NADH-quinone oxidoreductase subunit NuoB.	6.5693e-102
NZ_CP047147.1|WP_003948741.1|2859637_2860333_-|demethylmenaquinone-methyltransferase	gnl|CDD|234689	PRK00216, ubiE, bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE.	1.68769e-128
NZ_CP047147.1|WP_031178386.1|2867901_2868363_-|membrane-protein	gnl|CDD|227296	COG4961, TadG, Flp pilus assembly protein TadG [Intracellular trafficking and secretion].	0.00224039
NZ_CP047147.1|WP_008409043.1|2853470_2854226_-|NADH-quinone-oxidoreductase-subunit-C	gnl|CDD|181115	PRK07785, PRK07785, NADH dehydrogenase subunit C; Provisional.	6.41429e-155
NZ_CP047147.1|WP_086014568.1|2868359_2868737_-|septum-determining-protein	gnl|CDD|377921	pfam07811, TadE, TadE-like protein. The members of this family are similar to a region of the protein product of the bacterial tadE locus. In various bacterial species, the tad locus is closely linked to flp-like genes, which encode proteins required for the production of pili involved in adherence to surfaces. It is thought that the tad loci encode proteins that act to assemble or export an Flp pilus in various bacteria. All tad loci but TadA have putative transmembrane regions, and in fact the region in question is this family has a high proportion of hydrophobic amino acid residues.	9.77059e-06
NZ_CP047147.1|WP_018468568.1|2847345_2849874_-|NADH-quinone-oxidoreductase-subunit-G	gnl|CDD|236118	PRK07860, PRK07860, NADH dehydrogenase subunit G; Validated.	0
NZ_CP047147.1|WP_018468576.1|2868838_2869216_-|pilus-assembly-protein	gnl|CDD|377921	pfam07811, TadE, TadE-like protein. The members of this family are similar to a region of the protein product of the bacterial tadE locus. In various bacterial species, the tad locus is closely linked to flp-like genes, which encode proteins required for the production of pili involved in adherence to surfaces. It is thought that the tad loci encode proteins that act to assemble or export an Flp pilus in various bacteria. All tad loci but TadA have putative transmembrane regions, and in fact the region in question is this family has a high proportion of hydrophobic amino acid residues.	1.17719e-09
NZ_CP047147.1|WP_008415886.1|2861047_2862247_-|dehypoxanthine-futalosine-cyclase	gnl|CDD|274731	TIGR03699, menaquin_MqnC, dehypoxanthine futalosine cyclase. members of this protein family are involved in menaquinone biosynthesis by an alternate pathway via futalosine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone].	0
NZ_CP047147.1|WP_030308501.1|2858333_2858840_+|GNAT-family-N-acetyltransferase	gnl|CDD|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	6.97011e-23
NZ_CP047147.1|WP_030772685.1|2851219_2852056_-|NADH-quinone-oxidoreductase-subunit-NuoE	gnl|CDD|181024	PRK07539, PRK07539, NADH-quinone oxidoreductase subunit NuoE.	8.21571e-88
NZ_CP047147.1|WP_018468570.1|2856058_2856847_+|C40-family-peptidase	gnl|CDD|366353	pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.	2.9911e-28
NZ_CP047147.1|WP_003948732.1|2849870_2851220_-|NADH-quinone-oxidoreductase-subunit-NuoF	gnl|CDD|131014	TIGR01959, NADH-quinone_oxidoreductase_subunit_F, NADH-quinone oxidoreductase, F subunit. This model describes the F chain of complexes that resemble NADH-quinone oxidoreductases. The electron acceptor is a quinone, ubiquinone, in mitochondria and most bacteria, including Escherichia coli, where the recommended gene symbol is nuoF. This family does not have any members in chloroplast or cyanobacteria, where the quinone may be plastoquinone and NADH may be replaced by NADPH, nor in Methanosarcina, where NADH is replaced by F420H2. [Energy metabolism, Electron transport].	0
NZ_CP047147.1|WP_003948739.1|2856944_2858231_-|geranylgeranyl-reductase-family-protein	gnl|CDD|273936	TIGR02032, Uncharacterized_protein_MJ1520, geranylgeranyl reductase family. This model represents a subfamily which includes geranylgeranyl reductases involved in chlorophyll and bacteriochlorophyll biosynthesis as well as other related enzymes which may also act on geranylgeranyl groups or related substrates. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll].	9.4882e-102
NZ_CP047147.1|WP_008409042.1|2852091_2853471_-|NADH-quinone-oxidoreductase-subunit-D	gnl|CDD|180385	PRK06075, PRK06075, NADH-quinone oxidoreductase subunit D.	0
NZ_CP047147.1|WP_008415881.1|2863805_2866745_-|membrane-protein	gnl|CDD|198111	smart01043, BTAD, Bacterial transcriptional activator domain. Found in the DNRI/REDD/AFSR family of regulators. This region of AFSR along with the C terminal region is capable of independently directing actinorhodin production. This family contains TPR repeats.	5.88048e-09
NZ_CP047147.1|WP_159312421.1|2862289_2862949_-|flavin-reductase-family-protein	gnl|CDD|224766	COG1853, COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only].	5.11057e-28

Protein sequences

>NZ_CP047147.1|WP_030308501.1|2858333_2858840_+|GNAT-family-N-acetyltransferase
MTNPPPAIGLRVPTEEDAYAWHRAFDDPEVMEFLGGKSAERSVYEEMTARQRRHDAEHGFCFWTLTDARGEVLGFTGAQPWPHDWSPAVGQIEIGWRLTRSAWGQGYVTAAARETLERVRAAGVEEVVALVDAANHRSSAVARRLGMGGPEEFRTPSGRAALCYRLKL
>NZ_CP047147.1|WP_003948739.1|2856944_2858231_-|geranylgeranyl-reductase-family-protein
MNEPRTEQTADVIVVGAGPAGSTTAYHLAKAGLDVLLLEKTAFPREKVCGDGLTPRATKQLVAMGIDISEEAGWLRNKGLRIIGGGHRLQLDWPDLASFPDYGLVRKRDDFDEQLARQAQKAGARLHERCNVGAPITDPRTGRITGVEAKLGEEKTPVTFHAPLVVAADGNSTRLSLAMGLHRREDRPMGVAVRTYFTSPRHDDDYLESWLELWDKRGPGPDRLLPGYGWVFGMGDGTSNVGLGVLNTSASFKELDWREVLKAWCASMPEEWGYTEENMTGPIRGAALPMAFNRQPHYTKGLLLVGDAGGLVNPFNGEGIAYAMESGQIAADVIVQAHARSTPAQRERALLGYPKVLKETYGGYYSLGRAFVKLIGNPKVMKLATERGLTHPVLMRFTLKMLANLTDPTGGDAMDRVINGLTKVAPKA
>NZ_CP047147.1|WP_018468570.1|2856058_2856847_+|C40-family-peptidase
MALRAGVAGGVLSTIAVAGSANAATAAEPVTETIEMPTLTATLTSKAALSAEATQQAADAYQYRAEQQSAAEKAVKDAKKAHKAAEKKAEAAAKKKAEERAAAAERAARSAERTDLSGVQTAAATSSSSGSSASAPSQDVPAPASGSVASVISFLQAQVGDAYVMGGTGPNSWDCSGLVQAAFKQVGVDLPRTSQEQSTAGTQVGTSNLQVGDILYWGGQGSAYHTGVYIGDGKYLDAANPSKGVVIQDLSGYPADGAVRVL
>NZ_CP047147.1|WP_003948737.1|2854828_2855188_-|NADH-quinone-oxidoreductase-subunit-A
MNAYAPILVLGALGAAFAVFSVVMATLIGPKRYNRAKLEAYECGIEPTPTPAGGGRFPIKYYLTAMLFIVFDIEIVFLYPWAVSFDALGLFGLVEMLLFVLTVFVAYAYVWRRGGLEWD
>NZ_CP047147.1|WP_003948736.1|2854222_2854777_-|NADH-quinone-oxidoreductase-subunit-B
MGLEEKLPSGFLLTTVEQAAGWVRKSSMFPATFGLACCAIEMMTTGAGRYDLARFGMEVFRGSPRQADLMIVAGRVSQKMAPVLRQVYDQMPNPKWVISMGVCASSGGMFNNYAIVQGVDHIVPVDIYLPGCPPRPEMLVDAIVKLHQKVQSSKLGVNKEEAAREAEEAALKALPTIEMKGLLR
>NZ_CP047147.1|WP_008409043.1|2853470_2854226_-|NADH-quinone-oxidoreductase-subunit-C
MSDTHQDPEEPREESALPAARREGGDVIGVRRGMFGAQDTGDTSGYGGLVRTVSLPGPASRPYGGPTSREGYGVFDEIADELEGALDEQGLLPANAIDRTVVDRGELTFHIEREHLLRVARTLRDDPALRFELCTGVSAVHYPEDKGRELHAVYHLRSITHNRLIRLEVSAPDADPHIPSLVSVYPTNDWHEREAYDFFGLIFDGHPALTRLMMPDDWQGHPQRKDYPLGGIAVEYKGAQIPAPDQRRSYS
>NZ_CP047147.1|WP_008409042.1|2852091_2853471_-|NADH-quinone-oxidoreductase-subunit-D
MSTSHPRQEAGHATAAEEDAVGYSAGRETTEGTVYTVTGGDWDEIAEAAAKSDDERIIVNMGPQHPSTHGVLRLILEIDGETVTEARCGIGYLHTGIEKNLEYRTWTQGTTFVTRMDYLTPFYNEAAYCLGVEKLLGIEDQVPDRASVIRVLLMELNRLSSHLVAIATGGMELGATTIMIYGFRDREVVLDLFELITGLRMNHAFIRPGGLAQDLPAGALDQVREGVKTLRKNIDEYDKLATGNPLFQGRMKGIGYLDLAGCMSLGITGPVLRSTGLPHDLRKTDPYCGYETYDFEVPTADTCDSYGRFLIRLAEMRESLKIVEQCLDRLREPGEVMVSDKKIAWPAQLALGPDGLGNSLDHIKKIMGTSMESLIHHFKLVTEGFRVPPGQAYAAVESPKGELGAHVVSDGTTRPYRVHFRDPSFTNLQAVAAMCEGGQVADVIVAVASIDPVMGGVDR
>NZ_CP047147.1|WP_030772685.1|2851219_2852056_-|NADH-quinone-oxidoreductase-subunit-NuoE
MPQLPAPAYPAETHARLKADAEAIIARYPDSRSALLPMLHLVQSEEGYVTRTGMAFCAELLGLTTAEVTAVATFYTMYRRKPSGDYQVGVCTNTLCAVMGGDAIFDELKEHLGVGNDETTEDGKITLEHIECNAACDYAPVVMVNWEFFDNQTPDSAKRLVDDLREGRTVEPTRGAPLCTYKETARILAGFPDERPGAVEATGGAGPASLIGLKLAKGELPQQRVVHPRGQDGAPDATGHAPSPAEHLSSHDAPQQTAPSDPENPAGPVTGDGSEEGK
>NZ_CP047147.1|WP_003948732.1|2849870_2851220_-|NADH-quinone-oxidoreductase-subunit-NuoF
MTVATEMNQTSPDKLLAPVLSAFWDQPESWTLETYRRHDGYEGLRKALAMSPDDLIAYVKDAGLRGRGGAGFPTGMKWQFIPQGDGKPHYLVVNADESEPGTCKDIPLLFANPHSLIEGIVIACYAIRSSHAFIYLRGEVVPVLRRLHEAVREAYEAGYLGKDVLGSGLDLDLTVHAGAGAYICGEETALLDSLEGRRGQPRLRPPFPAVAGLYACPTVVNNVESIASVPAILQQGKEWFRSMGSEKSPGFTLYSLSGHVAGPGQYEAPLGITLRQLLDMSGGMRPGHRLKFWTPGGSSTPMFTDEHLDVPLDYEGVGAAGSMLGTKALQCFDETTCVVRAVTRWTEFYAHESCGKCTPCREGTYWLVQLLRDIEAGQGKMSDLDKLNDIADNINGKSFCALGDGAASPIFSSLKYFRDEYEQHITGKGCPFDPAKSTLWADQHLEAKA
>NZ_CP047147.1|WP_018468568.1|2847345_2849874_-|NADH-quinone-oxidoreductase-subunit-G
MTVTTGAAPGTPAGVPPEDLVTLTIDGIEISVPKGTLVIRAAELLGIEIPRFCDHPLLDPAGACRQCIVEVEGQRKPMASCTITCTEGMEVRTQLTSPVAEKAQRGVMELLLINHPLDCPVCDKGGECPLQNQAMQVGDPDSRFEGKKRTYEKPVPISTQVLLDRERCVLCARCTRFSNQVAGDPMIELIERGALQQVGTGDGDPFESYFSGNTIQICPVGALTSAAYRFRSRPFDLVSSPSVCEHCAGGCATRTDHRRGKVMRRLAADDPEVNEEWMCDKGRFGFRYAQSPERLTQPLVRSESGVLEPASWPEALQAAARGLNAARGRAGVLTGGRLTVEDAYAYSKFARVALDTNDIDFRARPHSGEEADFLASQVAGRGRDLDGGGLTYADLEQAPAVLLAGIEAEEEAPGVFLRLRKAWRKKGQRTFALATHTTRGLTKAGGTLLPAAPGTETEWLKALGTGFGLEGVGQEAGEALRAEGSVIVVGERLATVEGGLTAAVRAAAALGARLVWIPRRAGERGAVEAGALPSLLPGGRPATDPRARDEVAAAWGVAELPPRYGRDTGQIVEAAASGELTALLVGGVEVADLPDPARARQALDRAEFVVSLEQRPSEVTERADVVLPVAAVAEKSGTFLNWEGRSRMFEAALKPEQMTRRLAPGDLRVLHMLADAVAEADETGRGELALPDIRAARRELDRLGGWDARPSRPAVPPEAPAGSALPRPAAGEAVLAGHRMLLDQGLLQRGDEALAGTRHAAPARLSAATAAEIGAADGTVLTVAGPAGSVELPLLVTDMPDRVVWLPLNSTGTGVASDTGAVPGQLVRIAPAAEAPAEVEES
>NZ_CP047147.1|WP_003948741.1|2859637_2860333_-|demethylmenaquinone-methyltransferase
MTRASLDKQPQEVASMFDDVAAHYDLTNDVLSLGQARLWRKEVARAVDARPAQKILDLAAGTATSSQPFARAGAYVVPCDFSLGMLQVGKGRHPWMPFTAGDAMRLPFRDDTFDAVTISFGLRNVQDTSAALAELYRVTKPGGRVVICEFSQPTWAPFRSVYTEYLMRALPPVARAVSSNPDAYVYLAESIRAWPDQPALAGLLQEAGWGRVAWRDLTGGIVALHRGYKAP
>NZ_CP047147.1|WP_159312420.1|2860400_2861033_-|hypothetical-protein
MLTLHTAPLLLPPGAAPLPDGAVLVQGEAVLAVGPRADLAAAHPGARVRAWPGLLTTGLTHARALPLLEAAYHPDPREYDQLGETPLTGEALARLAPDRTRRSGSVRRGLQRLLRHGVTRVAGAVTDPAVRSALARSGVSVVPGPASAPGPVSFDPFTGGHDALSGVPLAPGVRADLAAFDVPDAAALRDGGAAACVATVLAGRLVHRAR
>NZ_CP047147.1|WP_008415886.1|2861047_2862247_-|dehypoxanthine-futalosine-cyclase
MTEKADLQSVLDRAAAGGRITPEEAVALYRDAPLHALGTAADAVRRRRYAGTEHIATYIIERNINYTNVCVTACRFCAFYAAPKDTAKGWTRDLDDILRRCAETIELGGTQIMFQGGHHPDFGVEYYEKHFAAIKKEFPELVIHSLGASEVEHMARISKTTVEDAIERIHAAGLDSFAGAGAELLPARPRKAIAPLKESGERWLEIMETAHRLGVESTSTMLMGTGETNAERIEHLRMIRDSQDRTGGFRAFIPYTYQPENNHLKGRTQATLFEYLRMIAIARLFLDNVAHIQGSWLTTGKEVGQLSLHYGADDLGSIMLEENVVSSAGAKHRSNRLEIIDLIRKAGRVPAQRATTYEHLVVHDDPANDPVDDRVASHISSIAIDGGTAHPELKLLAPN
>NZ_CP047147.1|WP_159312421.1|2862289_2862949_-|flavin-reductase-family-protein
MHVVPGLKVLYFGTPVVLVGTRNEDGTANLAPISSAWWLGQYAMLGLGDVARTTANLLREGECVLSLPSPALADAVDRLALTTGRPDVPERKAKQGYRYEPEKFAAAHLTEQPAELVRAPRVAECPVQLECRVVASHPFGGPGMHATAFQVEVLRTHVEEDLVIPGTHHVDPDGWDPLIMKFCEFYGGGHRLRPSRLADGWEMPHQRPGGERTTQNRRA
>NZ_CP047147.1|WP_159312422.1|2863080_2863809_-|prepilin-peptidase
MTGPLWLAPLAALWGAGWGALLPRAAYRFAAPAGEEWHTACPQGHPLGGWLGGPNCPDCRTPLGRRALPVLLAAALCAGLALTTGPRPELAVWLLAAPVGLLLAMVDLRVMRLPDPLTLPLAAGVLALLGVAAALPGAAGSWLGALYGLLALGGGAFVLFLINPDGFAFGDVKLCLALGAALGWYGLGAVFLGAFAGLLVGAVHGLFLVLAKGAGRRTAFAFGPSLLAGAYGVLLVAGAAAA
>NZ_CP047147.1|WP_008415881.1|2863805_2866745_-|membrane-protein
MARRTPQSSTRSTRQPQPQPLPRTRRTFGDFAKAVLAFLALAVLVVGVPLALASVIGWPLPDEAPSLDMLQREITVDTFLNVLAVVVWFAWAQFTACVLVEVKAALSGVGLPSRVPGAGPSQALARQLVAAVLLLGATAASFSPGLGQLGQQLEGHQQPAAAAAQQTPGLFGQDRAAAQSAASAVAEQAGAQAEQAAAKPSAAKGDTKYYRIQPPEGRHHDSLWEISERHLGDGRRYHEIYQLNKDRVQPDGSRLSEASLIRPGWIMEMPADATGGELVEMPDEAPKVSEELREQIADYAKSGDTATGGGSAAQEQKPDTGATDRDTQQISIPTERPAEQPQVAAPAAEGFSFGLPEALITAPLLAAGLLGALGRRRRAALWQSAMSAVGGRRGMEPPVPAGSAADVQDALLIGADPEGVRLLDRSLRGLAASLADESRPLPTVYAAWLSDGDLHLQLAQPAGEPPAPWQTGQDETFWMLARADGERYGDSEAAAPFPGLVSLGTLDDSRLLLNLEAVPGIVSLSGAAADRDAVFASVAAELATSGWSDRMTVTLVGFGEELTAIAPTRLRHLDGVPALLETMEAETRQRRGALGTAGHDSVLTGRTGPAQHTRWAPHLVLLAAEPTAEEATRLAELAADAPRLGFGYFIGTESGELPGAAWEMEITPEGRLLAPLLGLELDAQRVEAAEQRALVDLFTTADPDHEPEPGAAPPPFLVDVTEQGRPAVYARMVGPYEIIGIDAPDGSRSLLLHEALAQLLLHREGVHVRVLASALWPRGVTEDVRDALVDRLRDWLGTDEDGTPRLTTDEAGRLHLAKSVVSDLDVLRSLYHEATQGRGATDRAVRGRALTDALGLVRGPLLADRPEGRYGWLSHEIVDAQLPLLVADIGLALSAFHLEKERAGKAIEALERALSTAPDDERLWNELLRATHASGDTEALARRAADLVTRSGARGLPPRTEALLDELLPAWRDTASAAG
>NZ_CP047147.1|WP_031178386.1|2867901_2868363_-|membrane-protein
MTLPARLRAAADRRRLDDRGSGAGAVIIFALVFLTLAAFVIDGGLSISKRERAADIAEQAARYAAQDIDREALYEDEGGPAPINYANCGARVRQFAAEMGMNGADIAASGCVAASVDQVEVEIQLTYDPVFTGMFYGGAVTVKGRSTAENAVG
>NZ_CP047147.1|WP_086014568.1|2868359_2868737_-|septum-determining-protein
MSTIEVVILAPVMILFILVLVAFGQLVDGRGALDGAARDAARAGSIQKDHGTALAEARRAAEANLADVCTGPVSVRQTSAGFEPDTLFTVEVSCQIRGLAMIGVNVPTTLTASFSSPLDPFRRTA
>NZ_CP047147.1|WP_018468576.1|2868838_2869216_-|pilus-assembly-protein
MTAIEFVFLTPILFFMIFATVQFALYFFADHVAQAAAQAGARKARATADENPGGWRGEARTVTNAYIRQLGPQLVVSPNVTMLQPEPNTVGVEITARIPTVFPGLDLTVHAQSSGPVERFVEEGG
>NZ_CP047147.1|WP_008415871.1|2869453_2869702_-|hypothetical-protein
MRFGRSFSHPAVDFLITFLQARVERARDENTDRGASAVEWVIISAVVVAIVGVVAAILNAALSEGANKVGDCIKGADAGSTC

Crispr_ID: NZ_CP047147_12

• CRISPR_ID: NZ_CP047147_12
• CRISPR_location: 2935775-2935880
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP047147_12

Consensus_repeat	Method
CAGCCCGGCCGGCGCTTGAGGCCA	CRISPRCasFinder

spacers of NZ_CP047147_12

>12.1|2935799|58|NZ_CP047147|CRISPRCasFinder
CGGCCGGCGCTTGAGGCCATCTTGTACGCACGCGGACGCTCCGGACCCCGGCCAAATC

CRISPR arrays and Neighbor proteins around NZ_CP047147_12

CRISPR arrays

The CRISPR arrays of NZ_CP047147_12

>merge|NZ_CP047147|12|2935775-2935880|CRISPRCasFinder
CAGCCCGGCCGGCAATCGACAGCCCGGCCGGCGCTTGAGGCCATCTTGTACGCACGCGGACGCTCCGGACCCCGGCCAAATCCAGCCCGGCCGGCGCTTGAGGCCA

>NZ_CP047147|12|11|2935775-2935880|CRISPRCasFinder
CAGCCCGGCCGGCAATCGACAGCC	CGGCCGGCGCTTGAGGCCATCTTGTACGCACGCGGACGCTCCGGACCCCGGCCAAATC
CAGCCCGGCCGGCGCTTGAGGCCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_129817433.1|2931950_2932457_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379112
NZ_CP047147.1|WP_008403618.1|2935979_2937173_-|RtcB-family-protein	unknown	unknown	gnl|CDD|376465
NZ_CP047147.1|WP_159312440.1|2947240_2948560_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379262
NZ_CP047147.1|WP_067413040.1|2942120_2943893_-|lysine--tRNA-ligase	unknown	unknown	gnl|CDD|234829
NZ_CP047147.1|WP_018470421.1|2939385_2940285_-|CDP-diacylglycerol--serine-O-phosphatidyltransferase	unknown	unknown	gnl|CDD|224104
NZ_CP047147.1|WP_003948828.1|2944061_2945861_+|arginine--tRNA-ligase	unknown	unknown	gnl|CDD|215160
NZ_CP047147.1|WP_018470426.1|2948727_2949453_+|DUF4232-domain-containing-protein	unknown	unknown	gnl|CDD|379419
NZ_CP047147.1|WP_159313895.1|2934052_2935486_-|sodium-independent-anion-transporter	unknown	unknown	gnl|CDD|223732
NZ_CP047147.1|WP_003948819.1|2933859_2934069_+|hypothetical-protein	unknown	unknown	gnl|CDD|236658
NZ_CP047147.1|WP_031178407.1|2928234_2929266_+|sporulation-protein	unknown	unknown	gnl|CDD|369195
NZ_CP047147.1|WP_015507684.1|2930499_2931603_-|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|274934
NZ_CP047147.1|WP_003948818.1|2933078_2933852_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|226674
NZ_CP047147.1|WP_159312437.1|2932536_2932968_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|182266
NZ_CP047147.1|WP_018470414.1|2929394_2929679_+|Sec-independent-protein-secretion-pathway-component	unknown	unknown	gnl|CDD|234797
NZ_CP047147.1|WP_159312439.1|2945936_2947148_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl|CDD|224089
NZ_CP047147.1|WP_033240012.1|2938466_2939303_+|DUF3558-domain-containing-protein	unknown	unknown	gnl|CDD|378803
NZ_CP047147.1|WP_159312436.1|2929777_2930503_-|oxidoreductase	unknown	unknown	gnl|CDD|274935
NZ_CP047147.1|WP_159312438.1|2940605_2942036_+|DUF2637-domain-containing-protein	unknown	unknown	gnl|CDD|378511
NZ_CP047147.1|WP_078842895.1|2927433_2928063_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_051721650.1|2937408_2938341_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_129817433.1|2931950_2932457_+|GNAT-family-N-acetyltransferase	gnl|CDD|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	8.44365e-14
NZ_CP047147.1|WP_008403618.1|2935979_2937173_-|RtcB-family-protein	gnl|CDD|376465	pfam01139, RtcB, tRNA-splicing ligase RtcB. This family of RNA ligases (EC:6.5.1.3) join 2',3'-cyclic phosphate and 5'-OH ends. They catalyze the splicing of tRNA and may also participate in tRNA repair and recovery from stress-induced RNA damage.	7.92445e-179
NZ_CP047147.1|WP_159312440.1|2947240_2948560_-|helix-turn-helix-domain-containing-protein	gnl|CDD|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	3.16379e-09
NZ_CP047147.1|WP_067413040.1|2942120_2943893_-|lysine--tRNA-ligase	gnl|CDD|234829	PRK00750, lysK, lysyl-tRNA synthetase; Reviewed.	0
NZ_CP047147.1|WP_018470421.1|2939385_2940285_-|CDP-diacylglycerol--serine-O-phosphatidyltransferase	gnl|CDD|224104	COG1183, PssA, Phosphatidylserine synthase [Lipid metabolism].	2.02307e-36
NZ_CP047147.1|WP_003948828.1|2944061_2945861_+|arginine--tRNA-ligase	gnl|CDD|215160	PLN02286, PLN02286, arginine-tRNA ligase.	0
NZ_CP047147.1|WP_018470426.1|2948727_2949453_+|DUF4232-domain-containing-protein	gnl|CDD|379419	pfam14016, DUF4232, Protein of unknown function (DUF4232). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 177 and 242 amino acids in length. Many members of this family are lipoproteins.	1.29238e-13
NZ_CP047147.1|WP_159313895.1|2934052_2935486_-|sodium-independent-anion-transporter	gnl|CDD|223732	COG0659, SUL1, Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism].	1.33724e-111
NZ_CP047147.1|WP_033240012.1|2938466_2939303_+|DUF3558-domain-containing-protein	gnl|CDD|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	0.00120785
NZ_CP047147.1|WP_031178407.1|2928234_2929266_+|sporulation-protein	gnl|CDD|369195	pfam07070, Spo0M, SpoOM protein. This family consists of several bacterial SpoOM proteins which are thought to control sporulation in Bacillus subtilis.Spo0M exerts certain negative effects on sporulation and its gene expression is controlled by sigmaH.	9.38989e-101
NZ_CP047147.1|WP_003948819.1|2933859_2934069_+|hypothetical-protein	gnl|CDD|236658	PRK10153, PRK10153, DNA-binding transcriptional activator CadC; Provisional.	0.00130046
NZ_CP047147.1|WP_003948818.1|2933078_2933852_+|SDR-family-oxidoreductase	gnl|CDD|226674	COG4221, COG4221, Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only].	5.13064e-89
NZ_CP047147.1|WP_159312437.1|2932536_2932968_+|GNAT-family-N-acetyltransferase	gnl|CDD|182266	PRK10146, PRK10146, aminoalkylphosphonate N-acetyltransferase.	7.19452e-10
NZ_CP047147.1|WP_018470414.1|2929394_2929679_+|Sec-independent-protein-secretion-pathway-component	gnl|CDD|234797	PRK00575, tatA, Sec-independent protein translocase subunit TatA.	4.88644e-13
NZ_CP047147.1|WP_159312439.1|2945936_2947148_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl|CDD|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	1.68206e-130
NZ_CP047147.1|WP_159312436.1|2929777_2930503_-|oxidoreductase	gnl|CDD|274935	TIGR04037, predicted_flavoprotein, LLM-partnered FMN reductase, CE1759 family. This family represents a distinct clade within pfam03358. That family includes enzymes such as the NADH-dependent FMN reductase MsuE. Members of the present family regularly co-occur in genomes, typically as gene pairs, with members of TIGR04036, a probable FMN-dependent member of the bacterial luciferase-like monooxygenase (LLM) family. At least one member, RF|YP_001509627.1 from Frankia sp. EAN1pec, is fused to the LLM protein. The function of these gene pairs is unknown.	7.98664e-97
NZ_CP047147.1|WP_015507684.1|2930499_2931603_-|LLM-class-flavin-dependent-oxidoreductase	gnl|CDD|274934	TIGR04036, family_protein, putative luciferase-like monooxygenase, FMN-dependent, CE1758 family. This tightly conserved subfamily of the bacterial luciferase-like monooxygenase (LLM) family, with members showing > 60 % pairwise sequence identity, includes proteins from both species with and species without the ability to make coenzyme F420. Therefore, the like cofactor is FMN rather than F420. The presence of three members in Kineococcus radiotolerans SRS30216 and two in Saccharopolyspora erythraea NRRL 2338 suggest closely related (subfamily) rather than exactly conserved (equivalog) function. Gene neighborhoods around members are not conserved. [Unknown function, Enzymes of unknown specificity].	0
NZ_CP047147.1|WP_159312438.1|2940605_2942036_+|DUF2637-domain-containing-protein	gnl|CDD|378511	pfam10935, DUF2637, Protein of unknown function (DUF2637). This family of proteins has no known function.	1.52565e-39

Protein sequences

>NZ_CP047147.1|WP_159313895.1|2934052_2935486_-|sodium-independent-anion-transporter
MSPRRLWTEVLAGLVVALALIPEVISFSVIAGVEPAVGLFASFTTAVVISVVGGRPAMISAAAGAVALVIAPLNREHGLGYLIAAVILGGVIQIVLGVLGVARLMRFVPRAVMVGFVNALAVLIFLAQVPEMEHVPWAVYPLIVGGIALMVVFPRVTTVVPAPLVSIVVLTLITVGAGLAVPTVGDRGALPTSLPTPGLPDVPFTLDTLTLIAPYALALALVGLMESLLTAQLVDDLTDTPSDKRRESVGQGIANVVTGFFGGLGGCAMIGQTMVNVKTAGARTRLSTFLAGVFLLLLCLTLGPAVSAIPMAALVAVMVMVSFTTFDWRSIAPATLRRLPVGESAVMAVTVVFVVATHNLAVGVIAGCLAALGVFARRVAGRAELAVTRAPGGGTVRYAVTGDLFFASANGLADRFDYAGDPEKVVVDLGAARLWDASAVAVLDAITAKYAQRGKDAEVTGLTGAGAELHARLSERA
>NZ_CP047147.1|WP_003948819.1|2933859_2934069_+|hypothetical-protein
MTASAPGPEAPGPDPAPGPPERPVATPQERRRLAEETRTEKYVWWSLGYFFFGIHIVAFVMIYAVTHAR
>NZ_CP047147.1|WP_003948818.1|2933078_2933852_+|SDR-family-oxidoreductase
MSAAPTPGNRIAVVTGASSGIGAAGARKLAEAGYRVVLTARRKDRIEALAAELTEAGHSVTAYPLDVTDRAAVDEFATAFQKIAVLVNNAGGALGADPVASSSPDDWRQMYETNVIGTLNITQALLPALTASGDGTVVVISSTAGLATYEGGAGYVAAKHGEHVLAETLRLEIVGTPVRVIEIAPGMVKTDEFALTRFRGDTEKAAKVYAGVAEPLTAEDVADTVAWAVTRPSHVNVDLLVLRPRAQASNTKVHREL
>NZ_CP047147.1|WP_159312437.1|2932536_2932968_+|GNAT-family-N-acetyltransferase
MNIIDLAPGDPRLTADALPVLTELRPHLTPRLLEDVYAAGHPQGLRYTALYDVEGRCVAVAGWRVIANTSAIRKLYVDDLVTAEAARSTGAGRELVAYLEDRARELDCRVLDLDSGTQRTDAHRFYLRERFSIRAFHFSKLLR
>NZ_CP047147.1|WP_129817433.1|2931950_2932457_+|GNAT-family-N-acetyltransferase
MPWSEEDFPLLVAGNSEEMTAHLGGPESAEALAARHRRYLALDEGGDAGGRMFRITAAPPGTAHRPAGAIGFWLSEWQGRQVWESGWHVLPDLHGHGIATSAARLVAARAQAAGGPRTLHAFPSPTHAASNGVCRKAGFTLAGEARVEYPKGTWVACNDWRIDLDTDG
>NZ_CP047147.1|WP_015507684.1|2930499_2931603_-|LLM-class-flavin-dependent-oxidoreductase
MQFGIFSVGDVTPDPTTGRTPTEAERIKAILRIAEKAEEVGLDVFATGEHHNPPFVPSSPTTMLGWVAARTENLILSTATTLITTNDPVKIAEDFAMLQHVADGRVDLMLGRGNTGPVYPWFGKDIREGIPLAIENYALLHKLWREDVVDWEGKFRTPLQSFTATPRPLDGVPPFVWHGSIRSPEIAEQAAYYGDGFFHNNIFWPMEHTKRMVRLYRNRYAHYGHGTPEQAIVGLGGQVFMRKNSQEAVREFRPYFDNAPVYGHGPSLEEFTSQTPLTVGSPQQVIERTLSFRKDVGDYQRQLFLMDHAGLPLKTVLEQLDILGEEVVPVLREEFAKDRPAGVPDAPTHASLRARARESADSEAVTK
>NZ_CP047147.1|WP_159312436.1|2929777_2930503_-|oxidoreductase
MTEFPLQSGERPAAEAPDDLADDPRFSANEPVSPSGPLRVVVVSAGLSVPSSTRLLADRLGEAVARDLGAAEVPVRVDTVELRDLANDIAQNFTAGFPGPKLTAALDQVTGADAVIAVTPIFTASYSGLFKSFFDVLDQEALTGKPVLIAATGGTARHSLALEHALRPLFAYLRAVVVPTAVYAASEDWGNTDGLNRRIDRAAGELAALLAGTGGRRAAPADRLEEVVPFAEQLAALRVQE
>NZ_CP047147.1|WP_018470414.1|2929394_2929679_+|Sec-independent-protein-secretion-pathway-component
MLGISELAVILLVIVAVLAVKRLPDLARSSGKAARILKSEAKAMKEESRQGVDGQDRPGQAVYYATEPLPEQQPRPADGRQGRPDPQNPGSRPA
>NZ_CP047147.1|WP_031178407.1|2928234_2929266_+|sporulation-protein
MVFKRLLGSLGVGGPTVDTVLDAAPGSGSAAVPGGALTGRVHLKGGGSDFDISEITLELIARVEAETEEGEQHGTVAFERYVVGGGFRLAAETEQVVPFSVVLPWETPVSELYGQPLGIVLGVRTELAVAGAKDKGDLDPLAVGPLPAQEAILEALGQLGFGFRSADLEYGRIGGTGQQLPFYQEIELSPAPQYAHAVNEIEVTFLAHPGGLEVVLEADKRGGMFTPGHDALTRFTVSHEDVASRDWAAEVDGWVRQLVEHRAAYGTHASYGHHDPYAGGHHGHHDGHHDGHRSGPGMGTAIAAGAAGLAVGVAGGLVAAEVVDEVGDFFEGDDDEDDGGDEG
>NZ_CP047147.1|WP_078842895.1|2927433_2928063_+|hypothetical-protein
MHRGGGLGEGTGDLGPRRARRGKHRRDAASRAQDQAPARGGVEPAREGTDRGETGQSEIRSGGRVGVTYKYFGAPNGATAARVPLSMRPEELGGDELGMGGMFTRIKPETVSAMVLTGIEGIPLHRVPPLELVVLHPDYAVVKLPMTVVDPLRGIGEESVGAAAFIWSTVPDRGGPSDAFNVYQLLHEWQDFSHRLHEAGHQPYCLVWP
>NZ_CP047147.1|WP_008403618.1|2935979_2937173_-|RtcB-family-protein
MAYQEIPGARVPIRMWADPAGVEEAAMRQLQNVATLPWIKGLAVMPDVHYGKGATVGSVIAMRDAVCPAAVGVDIGCGMSAVRTSLTANDLPGDLSRLRSRIEEAIPVGRGMHERPVDPTRTHGFGTNRWDAFWDRFDTVADSVHFRRERAAHQMGTLGSGNHFVEVCVDTDGDVWLMLHSGSRNIGKELADHHIGVARDLPHNQGLVDRDLAVFVADTPQMAAYRNDLFWAQEYARYNRTLMMDLLKQVVSREFKKARVAFEPEISCHHNYVSEERYDGMDLLVTRKGAIRAGSGDYGIIPGSMGTGSYIVKGLGNEASFNSASHGAGRRMSRNAAKRRFSLRDLAEQTRGVECRKDSGVVDEIPGAYKPIEQVIDQQRDLVEVVAQLKQVVCVKG
>NZ_CP047147.1|WP_051721650.1|2937408_2938341_+|hypothetical-protein
MARKAYPRRARVTGTLMLLVALGAAGCTGDPAAEDSPDAKPAGGQATTAQAEPGKYQTLPQPCRAVETGTLDAMLPGLAELDQEQRQKAYEGTSSVTYDSDRRTGCRWKVDSADAGHLLRIDFERVVSYSASVSDDARAQAVYGDRMKEADLPLPSDPREEQPERRADDSAKADRDEARATAPADDEAGQGASPETSEKPGKGEEEKEKGTGKSEEPADETVDPSAPAEGLEPRLLQELADDAFIDDQLTTSSSGSGQRTVTVVFRTSNVIVTVEYEAQPKQVAEVPDSASMQEKARELAVLLAERLSDV
>NZ_CP047147.1|WP_033240012.1|2938466_2939303_+|DUF3558-domain-containing-protein
MHRPAQRLTRILACAAVPVMLVAAGCSSDDSSGGKDAQQDKPASSSAASAPAVEKAAYGTLPEACSTLSKKTLKDLVPDADSLKGKTGKSDDTASRATCSWNSLDNKGVDGSQFRWLHVSLMRFDSDEALGSGAKRAEKYYAKQIADAKATEDAKKVAAEPVSGTGDAATVVSYELKKKEGTFKQQSLVTRVENVVVTVDYNGAGLAGQSSPKTAGLVEDATKAGKEAVAAVTKANSSDAKGSSDADSGKEPEKDADKKSTKEDDDDNAGQGAAPGKS
>NZ_CP047147.1|WP_018470421.1|2939385_2940285_-|CDP-diacylglycerol--serine-O-phosphatidyltransferase
MTTTDRDRAALRAEDTPEEPRRNAGRDVDQGVGGDVPGEAPGRSGRQPSPSRLSAADILTLGNAVCGFSSVYFITTAVLVPYLTGGPGDGTLRQGAATAVMLILLASLFDLCDGLVARKFRSSGMGAELDNLSDLISFGLAPAYFVVVWGLVGEGSHLWLTVVGAVAVLLAGVLRLARFSVTTSRDGMFEGMPIPFAALTVVSVVLLELPFALTLALVVGVAWLMVSRVEYPKPTGRMAVATVVWAAVNIGCLVAWAAGAPGAERLLVTGCALQLSLAALLPLVATGRRLKARRDRRSA
>NZ_CP047147.1|WP_159312438.1|2940605_2942036_+|DUF2637-domain-containing-protein
MAATELTRTHRILIGVVVAGAVVIAAIGFAGSYTAVRELALQKGFGTFSYFFPIGIDAGICVLLALDLLLTWMRIPFPMLRQTAWLLTAATIAFNGAAAWPDPLGVGMHAVIPVLFVVAVEAARHAIGRIADITADKHMEGVRITRWLLSPLPTFLLWRRMKLWELRSYEQVIKLEQERLVYQARLRSRFGRAWRRKAPVESLMPLRLARYGVPLAETAPAGLAAAGIEPALLPPAPAPARQELERADRPVAETDPAPAPTTSLEKQPADRPAAEAPQERQAPPPEGSPWFAGQQGPVQYEGTYDPQYEPDPQTFAEYQRYQRFAAHEAQEAQAAREAEVQQEAAEEERRDGVQVPAGPGRTRPLGGAPAIPAQREGEQPEESRPAPPQDEAPQVPGGGAIDEETFFAAFRRYVEVNGTYPNARKFGLYLQDHHQVSNEAGGPLPEGDLWPYLRECRRRYEQEQAQAAPEPDFTSA
>NZ_CP047147.1|WP_067413040.1|2942120_2943893_-|lysine--tRNA-ligase
MPIVAQSTETADWVSRYADEVIAEAERRAGAKKADGTADGAPGTDGLTVVVASGLSPSGPIHLGNLREVMTPHLVADEVRRRGHTVRHLISWDDYDRYRKVPAGVAGIDESWAEHIGKPLTAVPAPAGSAYPNWAEHFKAAMTEALDALGVEYDGISQTTQYTSGAYREQILHAMRHRGDIDAILAQYRTKKAPGKKSQKPVDEAELEAAEGSGAAAEDDGTTAGGGYYPYKPYCTVCNKDLTTVTSYDDETTELSYTCACGHAETVKLSTFDHGKLVWKVDWPMRWAYEGVIFEPSGVDHSSPGSSFQVGGQIVEIFDGVRPIGPMYAFVGISGMAKMSSSKGGVPTPADALKIMEPQLLRWLYARRRPNQSFKIAFDQEIQRLYDEWDKLEAKVAEGAALPADAAAHSRAAATAAGELPRTPRPLPYRTLASVADITAGAEDQTLRILSELDPAHPITGLDEVRPRLDRAEAWINTYVDAEARTVVRAEPDTEALAGLGDEARESLRLLLDGLDSHWSLDGLTTLVYGVPKIQAGFPADAKPTPELKAAQRSFFALLYQLLVGRDTGPRLPTLLLAVGEDRVRRLLGA
>NZ_CP047147.1|WP_003948828.1|2944061_2945861_+|arginine--tRNA-ligase
MASVTSLTASVHQRLADALAAALPEAGAADPLLRRSDRADYQANGILALAKKLKGNPRELATKVVDAIGADEVIQDIEVSGPGFLNLTLSDAAITRNLAARAADPARLGVPLAEAPGTTVIDYAQPNVAKEMHVGHLRSAVIGDAVVRMLEFTGEQVVRRHHIGDWGTQFGMLIQYLIEHPGELAATAESAAVEAGQASVEAGEQAMSSLNRLYKASRALFDSDEEFKTRARRRVVDLQAGDPETLAMWQRFVDESKVYFYSVFNKLDMEIHDADVVGESGYNAMLAETCRLLEESGVAVRSEGALCVFFDDVKGPDGQPVPLIVQKSDGGFGYAATDLSAIRDRVFQLKADTLLYVVDARQSLHFKMVFETARRAGWLGEDVKAVQLAFGTVLGKDGKPFKTREGETVRLVDLLDEAVERATAVVREKDVKEQLTEEQIAERGAEVGIGAVKYADLSTSAARDYKFDLDQMVSLNGDTSVYLQYAYARIRSILRRAGEARPVAHPELALAPAERALGLHLDQFGEIASDAAAEYAPHKLAAYLYQTASLYTTFYDQCHVLSADNPPELVENRLFLCDLTGRTLHQGMELLGIRTPEQL
>NZ_CP047147.1|WP_159312439.1|2945936_2947148_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MSLSPAATVPTPPLAGRAVGGGGSPVGDILAVTARPEVINFAGGLPARELFDAEGIAEAFRAVLAEQAPRALQYATTEGEPALRGALAGRMTARGLATEADDVLVTTGSQQGLSLVAQALIEPGDTVLVESPCYLAALQVFAFAGARIVPVACDDDGIDPAALEELVVRERPKFLYTVPTFQNPTGRTMTADRRREVARIAARRGLWIVEDDPYGELRFAGERLPWIASLPEAADRTVLLGSFSKVMAPGLRLGWLRAPRPLCAACALVKEGTDLHTPTVNQLAAARYLADNDLDAHVARVAAVYGTRRDALLAGLPDALPAGSTWTTPQGGMFVWARLPEGHDTAALLRTVVGFDVAYVPGAPFFAGRPDHGTLRLCFVTQTPDEIAEGLRRLEKGFAAAAG
>NZ_CP047147.1|WP_159312440.1|2947240_2948560_-|helix-turn-helix-domain-containing-protein
MGTADSTGEAERLAALLSTLKERSGLSYGALGKRLHLSASTLHRYCNGDAVPADFAPLNRFARLCRATPEELVEVHRRWILADAAREQRGKGAGGAAGGAAGSDAPAADPGTPADLPDADDTPKSPETPDTQEPPDSPSAPRPRPRRRLILAATAGVIAVAATAALLVGRLVDDGAGAGAGQAAGAARGPVASPEAAESPSPSPSGSASGKPSASPSPSGTPGASPGSTADGKPAAPAPTGVPFHASVRAHAWENQCSQRYLVDREPDAVRPPPVEQDAPAWVAAMGAVSADEQVVEVTLQGKGSETVVLQALHVRVVRTGEPLPWTDYGTGVGCGGGVALRTFDVDLDQGSPAARAAEGQRPFPYKISESDPEMFRVTAHTGGRDVSWYLEVEWSSGERQGVFRVDDRGRPFRTSASAGRPAYDYPPGASEWSEHTPG
>NZ_CP047147.1|WP_018470426.1|2948727_2949453_+|DUF4232-domain-containing-protein
MTATPRSRRLRTLAAALVTTAALSLTACQTGTADATGVVDSTQPPAPGTESAEKQSPATGTDSDTSGASNDSGDSKDSGSSVNSGSSGKEATQVADRKTAKKTTSCTAKGTKVTVTDAPRPINHLLIKATNTSDTTCHLYYAPYLRFDQAQSAVPFIEESKPQAVVTLEPGESGYAGVLTSTPDGSHPYDATSLTLYYAARSGQGSTGAPSHPALPFDSVRIDSSNAVTYWQTSAADALMW

Crispr_ID: NZ_CP047147_13

• CRISPR_ID: NZ_CP047147_13
• CRISPR_location: 3197722-3197808
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: WYL

Consensus repeat of NZ_CP047147_13

Consensus_repeat	Method
TGGCCTCAATCGCCGGCCGGGCT	CRISPRCasFinder

spacers of NZ_CP047147_13

>13.1|3197745|41|NZ_CP047147|CRISPRCasFinder
GTGGGTTGCCGGGCTCCGTCTCGACCGTGCCGGTCACTGAC

CRISPR arrays and Neighbor proteins around NZ_CP047147_13

CRISPR arrays

The CRISPR arrays of NZ_CP047147_13

>merge|NZ_CP047147|13|3197722-3197808|CRISPRCasFinder
TGGCCTCAATCGCCGGCCGGGCTGTGGGTTGCCGGGCTCCGTCTCGACCGTGCCGGTCACTGACTGGCCTCAAACGCCGGCCGGGCT

>NZ_CP047147|13|12|3197722-3197808|CRISPRCasFinder
TGGCCTCAATCGCCGGCCGGGCT	GTGGGTTGCCGGGCTCCGTCTCGACCGTGCCGGTCACTGAC
TGGCCTCAAACGCCGGCCGGGCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_008415458.1|3200334_3201078_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|272861
NZ_CP047147.1|WP_018895030.1|3189617_3190256_-|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme	unknown	unknown	gnl|CDD|274422
NZ_CP047147.1|WP_159312493.1|3202783_3203074_-|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
NZ_CP047147.1|WP_159312488.1|3194459_3194819_-|glyoxalase	unknown	unknown	gnl|CDD|319922
NZ_CP047147.1|WP_159312484.1|3188803_3189601_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159312494.1|3203226_3203436_-|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
NZ_CP047147.1|WP_003949028.1|3204846_3205584_-|HAD-family-phosphatase	unknown	unknown	gnl|CDD|223710
NZ_CP047147.1|WP_159312496.1|3204608_3204830_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159312486.1|3192103_3193543_-|rifampin-monooxygenase	unknown	unknown	gnl|CDD|235870
NZ_CP047147.1|WP_159312489.1|3194934_3195963_+|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	gnl|CDD|225253
NZ_CP047147.1|WP_159312490.1|3195959_3196685_+|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|379312
NZ_CP047147.1|WP_159312491.1|3198437_3199223_-|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|367243
NZ_CP047147.1|WP_159313902.1|3203432_3204263_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379262
NZ_CP047147.1|WP_129828615.1|3201690_3201900_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159312485.1|3190398_3191124_-|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|379312
NZ_CP047147.1|WP_018895032.1|3191218_3192073_+|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|366166
NZ_CP047147.1|WP_159312487.1|3193770_3194442_+|haloacid-dehalogenase-type-II	unknown	unknown	gnl|CDD|319787
NZ_CP047147.1|WP_159312492.1|3199328_3200342_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|130256
NZ_CP047147.1|WP_018470031.1|3196980_3197622_+|histidine-phosphatase-family-protein	unknown	unknown	gnl|CDD|366010
NZ_CP047147.1|WP_159312495.1|3204432_3204612_+|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP047147.1|WP_159312489.1|3194934_3195963_+|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	9.7e-34	112.0	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_008415458.1|3200334_3201078_+|ABC-transporter-permease	gnl|CDD|272861	TIGR00025, Mtu_efflux, ABC transporter efflux protein, DrrB family. The seed members for this model are a paralogous family of Mycobacterium tuberculosis. Nearly all proteins scoring above the noise cutoff are from high-GC Gram-positive organisms. The members of this paralogous family of efflux proteins are all found in operons with ATP-binding chain partners. They are related to a putative daunorubicin resistance efflux protein of Streptomyces peucetius. This model represents a branch of a larger superfamily that also includes NodJ, a part of the NodIJ pair of nodulation-triggering signal efflux proteins. The members of this branch may all act in antibiotic resistance.	6.90299e-14
NZ_CP047147.1|WP_018895030.1|3189617_3190256_-|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme	gnl|CDD|274422	TIGR03083, TIGR03083, uncharacterized Actinobacterial protein TIGR03083. This protein family pulls together several groups of proteins, each very different from the others. They share in common three conserved regions. The first is a region of about 38 amino acids, nearly always at the N-terminus of a protein. This region has a bulky hydrophobic residue, usually Trp, at position 29, and a His residue at position 37 that is invariant, so far, in over 150 instances. The second conserved region has a motif [DE]xxxHxxD. The third conserved region contains a hydrophobic patch and a well-conserved Arg residue. Most examples are found in the Actinobacteria, including the genera Mycobacterium, Corynebacterium, Streptomyces, Nocardia, Frankia, etc. The pattern of near-invariant residues against a backdrop of extreme sequence divergence suggests enzymatic activity and conservation of active site residues.	1.00587e-22
NZ_CP047147.1|WP_159312493.1|3202783_3203074_-|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	3.11813e-19
NZ_CP047147.1|WP_159312488.1|3194459_3194819_-|glyoxalase	gnl|CDD|319922	cd07261, EhpR_like, phenazine resistance protein, EhpR. Phenazine resistance protein (EhpR) in Enterobacter agglomerans confers resistance by binding D-alanyl-griseoluteic acid and acting as a chaperone involved in exporting the antibiotic rather than by altering it chemically. EhpR is evolutionarily related to glyoxalase I and type I extradiol dioxygenases.	8.47345e-32
NZ_CP047147.1|WP_159312494.1|3203226_3203436_-|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	1.07135e-18
NZ_CP047147.1|WP_003949028.1|3204846_3205584_-|HAD-family-phosphatase	gnl|CDD|223710	COG0637, COG0637, Predicted phosphatase/phosphohexomutase [General function prediction only].	1.68216e-10
NZ_CP047147.1|WP_159312486.1|3192103_3193543_-|rifampin-monooxygenase	gnl|CDD|235870	PRK06834, PRK06834, hypothetical protein; Provisional.	9.25536e-162
NZ_CP047147.1|WP_159312489.1|3194934_3195963_+|WYL-domain-containing-protein	gnl|CDD|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	1.51181e-27
NZ_CP047147.1|WP_159312490.1|3195959_3196685_+|methyltransferase-domain-containing-protein	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	2.99311e-21
NZ_CP047147.1|WP_159312491.1|3198437_3199223_-|TetR-family-transcriptional-regulator	gnl|CDD|367243	pfam02909, TetR_C, Tetracyclin repressor, C-terminal all-alpha domain.	6.42215e-11
NZ_CP047147.1|WP_159313902.1|3203432_3204263_-|helix-turn-helix-domain-containing-protein	gnl|CDD|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	1.21575e-09
NZ_CP047147.1|WP_159312485.1|3190398_3191124_-|methyltransferase-domain-containing-protein	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.68719e-18
NZ_CP047147.1|WP_018895032.1|3191218_3192073_+|alpha/beta-fold-hydrolase	gnl|CDD|366166	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	4.17344e-12
NZ_CP047147.1|WP_159312487.1|3193770_3194442_+|haloacid-dehalogenase-type-II	gnl|CDD|319787	cd02588, HAD_L2-DEX, L-2-haloacid dehalogenase. L-2-Haloacid dehalogenase catalyzes the hydrolytic dehalogenation of L-2-haloacids to produce the corresponding D-2-hydroxyacids with an inversion of the C2-configuration. 2-haloacid dehalogenases are of interest for their potential to degrade recalcitrant halogenated environmental pollutants and their use in the synthesis of industrial chemicals. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	2.35651e-42
NZ_CP047147.1|WP_159312492.1|3199328_3200342_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|130256	TIGR01188, drrA, daunorubicin resistance ABC transporter ATP-binding subunit. This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other].	1.55628e-108
NZ_CP047147.1|WP_018470031.1|3196980_3197622_+|histidine-phosphatase-family-protein	gnl|CDD|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	8.99884e-27

Protein sequences

>NZ_CP047147.1|WP_018470031.1|3196980_3197622_+|histidine-phosphatase-family-protein
MTSTAATGMASRTLYLARHGDAPGEGGLSAQGRRQAAFLGERLRGVPLSAIHHGPQARARETAEIVAAQRDDAEPVPRACDSAGDYVPYLPERREVASGLPEATWEWLLQLPERERLPGPELARDALRRFTGAVPGGVARHELVVTHNFVIGWLVREALDAPDWRWIGLHHANAALSIIHYAPEGPSSLIVYNDIRHLPEELRWTGFPPGLRV
>NZ_CP047147.1|WP_159312490.1|3195959_3196685_+|methyltransferase-domain-containing-protein
MTAPSAPTETTETADAATRASYDTVATTYEQLLRAELDARPLERALLAAFAELVRGPESGPVADLGCGPGRITAHLADLGVNAYGIDLSPGMVAVARERHPHLRFEEGTMVALRHRDGELGGAVAWYSTVHMEPGLLPGVYAEIHRVLAPGGRLLLAYKAGERVRHLDHAYGHPLSLDVYWVPPGEVEGLLRAAGFTVEATMTRRPDAGDGPRAGDQGFVLARKPLAVAGAEAGSLPKSGA
>NZ_CP047147.1|WP_159312489.1|3194934_3195963_+|WYL-domain-containing-protein
MTPDRFFALLLALQTRRDPVTTTDLAAETGVSVRTVLRDLRWLQDAGFPVLVERGRWGGVTLLPGGALDTARLTPAERDQLALHGLDDRQRHQLGAAADGRRAREKVAARASGAAGPPLPLSAVVTTDSRPWFWSGAQGLEPSALVGDVRRGVRLRIRYRRAAESAPAWQLVDPYGLLAKAGRWYLVADRSGTPRLYSLERLTDWRPTAAPRRLRPGISLADAVAELTTGWETSADLRIHGLLAVRHAERAQRILGSRVTVHRPGEGPALSPSPGPDQVALTLSCRNLEEVRQLLPFGADLLITDPPEARTRLRELAAEVVGQYVEQDEGDEGAGPTYPRPS
>NZ_CP047147.1|WP_159312488.1|3194459_3194819_-|glyoxalase
MTRPNMFIVHVSDAPESARFYGDLFAMEPVFEAPRFIAFELGGGVQLALWSGAAEGLSGPRTSEVCLNLDGAPASVDARHEEWTAKGVTIVEEPHDAVFGRTFVAADPDGNLIRVAPLD
>NZ_CP047147.1|WP_159312487.1|3193770_3194442_+|haloacid-dehalogenase-type-II
MSRRPDPQFVTFDMYGTLTDFPIGAAAEKTIEAISSPGQRDVFRRRFAAYQLDESMGDWRPYDELIARAFERACRSAGIPFRPADPAAVFDQIPTWGPHPDVPGPLARLAARHPLVILSNASDQHASRNAALLGAPLHAVYTAEQARAYKPRLGAFEYLYAQLGCRPEDTLHVSASPRYDLQSATDLGVRETVYLNRGYEPSAPHCHAYEVTALAGVAELLGV
>NZ_CP047147.1|WP_159312486.1|3192103_3193543_-|rifampin-monooxygenase
MIDVLVVGAGPTGLMLAAELRLHGVRTVVVEKDTEPTGHSRAQGLHVRSTEVMDQRGLLDQFLARGRQFRVGGFFAGLGPAWPEGMDTAHSYVLAIPQAETERLLAEHATGLGAEFRRGCALTGLEQDADGVTAGLADGTRLRARYLVGCDGGRSTVRKLLGTPFPGEPSRVDTLLGDVALTATPEELAAVTAEVRKTHLRYGAMPLGEGRYRVIVPDEGASEDRAAPPTLDHLRARLRAVGGTDFGAHDPRWISRFGDATRQAERYRTGRVLLAGDAAHVHPPTGGQGLNLGVQDAFNLGWKLAAEVNGWAPDGLLDSYHAERHPVGAAVLDNTRAQTELMNPGPGQRALRRLVAELMEFEEVNRHLIEKITAVAVRYDLGGGHPLVGRRLRDVRLGRGRLYELTHAGRGLLLDPAGRLSAGGWADRVDHVVDTGPELDELDVPAALLRPDGHVAWVGDDQEELAPALKRWFGEPAAG
>NZ_CP047147.1|WP_018895032.1|3191218_3192073_+|alpha/beta-fold-hydrolase
MPLSPTFVLVHGAFANSFSFAPLQAELGLLGHRSVAVDLPGHGFEATFPASYQAPQDFAALAAEPGAIKGVTLADNAARVIEALERARRNGPTVLVGHSRGGATITAVANARPDLIDRLVYVSAWCPVDLTVGDYYAEPEMASVDPMAFAPSLLGNPAELGLLRTNFRTSDPAALATFKEAFGADLTDDEFRTFLNTFQPDESLDAGTEADRAQAATWGTVPRTYVRLADDTSLTPAAQDRMIREADALTPGNPFDVHTLDGSHLRWLVHPGPAAAVLAGLAAG
>NZ_CP047147.1|WP_159312485.1|3190398_3191124_-|methyltransferase-domain-containing-protein
MADECFRHPRLAAVYDALDPDRGDLDAYVRAVGEFGARRVLDIGCGTGVFALLLAARGIEVVGVDPARASLDVARAKPGADRVRWICGDATGLPPLRADLATLTANAAQEITGPDAWRATLRGAYGALRPGGHLLFETRDPARRAWEEWTPEASRHTTEIPGHGAVESWVELREVRGPLVTFRWTYVFAADGQVLTSDSTLRFRERQEVEADLAAEGFEVVEVRDAPDRPGKEFVFVARRG
>NZ_CP047147.1|WP_018895030.1|3189617_3190256_-|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme
MTDPVWASIHAERAALAADLAGLTEEQWATPSLCSGLTVREVLAHLTASASLNAVRWMAGVIRCRFDFDRQVAVRLAEHLGATPAETLERFRSVVASTTKPPLPVVAMLGETLVHGEDIRRPLGLRRDHPVEVVTRVAAYYQGSDQVVVARSRVAGLRLVADDGPFTSGTGPLVSGPTLALVMAMTGRTACCDDLDGEGVELLRSRCGAGAA
>NZ_CP047147.1|WP_159312484.1|3188803_3189601_+|hypothetical-protein
MSLSGLSLSRWRSLDPPAARRLARQAADRAGGQVTAVETVEHLGAPLHRVRIACRGREFALIPGGEVTLGFDADGRRLPPGLEAGYAESAEQGYGYGPDLRSHLAQVLSPRRTVTVPTVLMAVEAEKLTAPPAGTPGLLAAEGLRMPSSDEWEHACGAGADTLFRWGDTCPLDRVPYGDDSGPHQQPNAFGLRIAHDTYDAELTSEPGAVHGGDGGESVCGGYGAVLAWLPLATAQRNPAMAEFVYGPDGEEMYEEFSTRPVLAL
>NZ_CP047147.1|WP_159312491.1|3198437_3199223_-|TetR-family-transcriptional-regulator
MAPPPPERRDPADETGLPASVEAAWGLRGRPTKGPRPGIGVERIVDAAVKLAATEGLQAVSMGRVAKELGASTMSLYRYVAAKDELFILMQEAATGLPPEDAPPPSAGWRARLAWFGHAYRGVLEANLWLLHIPISSPPATPNSVAWMEAGLDALDGTGLDEATKLGVMMLISGYVRSQAGLMADLTEAMRRSGRSAENTHRQYIHTLTRLADQRGPEAFPAVRRLLASQVLGEGDDADADFDWGLHRVLDGVQVLIEGRA
>NZ_CP047147.1|WP_159312492.1|3199328_3200342_+|ATP-binding-cassette-domain-containing-protein
MRQPPHAAVEVQGLSKSYGDHAVLRSVDLRVEQGGVLALLGPNGAGKTTTVRVLTTLTDPDAGSVRVAGYDVVTERRRAQRAISLTGQFAAVDETQTGAENLWTTARLAGLTRAAARRRAAELLERFALTDAGGRLVRTYSGGMRRRLDLAAGLVGEPRVLFLDEPTTGLDPRSRRQLWEVVRELAAAGTAVLLTTQYLEEADQLADRVAVLHGGRIAAEGTPEELKASAGQTVLEVTAADAAAFARLEARTPHPVAHRSPEMLALSFPTRGDARHLRTLLDELDPGRDEITAFHVRQATLDDVFMALTGAPATETTGTTGTTDTTGTTDAKEPSHV
>NZ_CP047147.1|WP_008415458.1|3200334_3201078_+|ABC-transporter-permease
MSEALTLAGRCLRMNRRDPEALFMAILLPVALMLVFVYFFGGAIDTGSAYVTYVVPGLLVLCAGYGSAGTAMRVTEDMRTGVVDRFRSMGVTGTPMLAGHVAASVVRNILATAMVLSVALLIGFRPAADPLAWLAAAGLLLAYLVAVSWLAAGVGLLARTPEGASGFTFFLMFLPYPSSAFVPIETMPTWLHGFAEHQPVTPLIESLRALLLDEPLGSAPWTALAWCGGILLIAVAASNALFRFRTR
>NZ_CP047147.1|WP_129828615.1|3201690_3201900_+|hypothetical-protein
MTTIILLLVMGIALILSRNIFARFASSQNTPFGRANAKHPKATSMGPVVIGSIMIIAAILGIFGALEPQ
>NZ_CP047147.1|WP_159312493.1|3202783_3203074_-|DUF397-domain-containing-protein
MTSNSPYWRKSSYSANGGDCVEVHIPPALDASPDWFKSSHSSNGGQCVEVAANLVPTHDLVPVRDSKTPSGSVLTFPATAFSSFVAGVKAGEFRSA
>NZ_CP047147.1|WP_159312494.1|3203226_3203436_-|DUF397-domain-containing-protein
MTTESPRWFKSSYSSNGGACVEVATNLVAPRGIVPVRDSKVHSGPVLTFQAAAFSSFVGGAKAGNFRSA
>NZ_CP047147.1|WP_159313902.1|3203432_3204263_-|helix-turn-helix-domain-containing-protein
MVNRKDLDPEESPAAEFGVLLRRLRDERGWTQEDLGARMRVSGTHISAVETNRRPPTPQFARSADRALGTGDLLARKVRAVRNTSLLEGFPEFVKQEIRAAELRLFELGIIPGLLQTPEYAAAITQGAVRRGAISEQQAEERLTLLAKRQTSLVRDPAPIVHVVLDESCLRRLVGGPHVMSAQLESIVAFGTLPNTVLQVAPYDLGERRSFDLPIHLLTLPERTFLAYSESAQQGMLERDYTAVQPLLTAYHQLQAEALSQTASMAMIEQVRKGIS
>NZ_CP047147.1|WP_159312495.1|3204432_3204612_+|hypothetical-protein
MSAVDSPHGKGAQPCTTCQSWKLAEAVANGEQDYSRATDCRVLLKRHRESAECGAGGEG
>NZ_CP047147.1|WP_159312496.1|3204608_3204830_+|hypothetical-protein
MSAGYEPPGKAYREFDPLRFPPCACEGCRRRAALESQAPPPTEPVPAPEQPRYVRCPMLGCGRLHPALPDDPR
>NZ_CP047147.1|WP_003949028.1|3204846_3205584_-|HAD-family-phosphatase
MTSSTHPPEPTADELAGLRDLVAAAKTVIVGFDGPLCRLYDPLTARTAADSLTALLAEHGVPAGDVPGRTPLALLRSLTLGALDDDPALSTALDELLTGSEVAATLTARPAPYADNLVRTWSAVGTRLAVATGHSADAVHAYLAGRGLTACFGPHVYGRTDGLTHLGHDAPPRALAALGADPAEALVLGSTPEDLRAARDAGAPFLGYARDLPAYDRLRAAGAPLVTGTLEPVRQAVWELNLPRR

Crispr_ID: NZ_CP047147_14

• CRISPR_ID: NZ_CP047147_14
• CRISPR_location: 3257522-3257624
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP047147_14

Consensus_repeat	Method
AGCCCGGCCGGCGTTTGAGGCCA	CRISPRCasFinder

spacers of NZ_CP047147_14

>14.1|3257545|57|NZ_CP047147|CRISPRCasFinder
GTCAGTGACCGGCACGGGCAACAACCGGCACCCCCAGTCGCGGCGCAGCCACACCCC

CRISPR arrays and Neighbor proteins around NZ_CP047147_14

CRISPR arrays

The CRISPR arrays of NZ_CP047147_14

>merge|NZ_CP047147|14|3257522-3257624|CRISPRCasFinder
AGCCCGGCCGGCGTTTGAGGCCAGTCAGTGACCGGCACGGGCAACAACCGGCACCCCCAGTCGCGGCGCAGCCACACCCCAGCCCGGCCGGCGCTTGAGGCCA

>NZ_CP047147|14|13|3257522-3257624|CRISPRCasFinder
AGCCCGGCCGGCGTTTGAGGCCA	GTCAGTGACCGGCACGGGCAACAACCGGCACCCCCAGTCGCGGCGCAGCCACACCCC
AGCCCGGCCGGCGCTTGAGGCCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_159312514.1|3252203_3253478_+|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|227277
NZ_CP047147.1|WP_159312516.1|3253967_3254975_+|ABC-transporter	unknown	unknown	unknown
NZ_CP047147.1|WP_018470074.1|3250506_3250881_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_010644928.1|3258517_3260728_+|RNA-degradosome-polyphosphate-kinase	unknown	unknown	gnl|CDD|235469
NZ_CP047147.1|WP_008411243.1|3262971_3263670_-|type-1-glutamine-amidotransferase-domain-containing-protein	unknown	unknown	gnl|CDD|153235
NZ_CP047147.1|WP_100458188.1|3250297_3250510_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159312513.1|3251797_3252169_+|hypothetical-protein	unknown	unknown	gnl|CDD|226318
NZ_CP047147.1|WP_030765598.1|3251133_3251577_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_018470081.1|3257710_3258151_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159312520.1|3262029_3262437_+|PIN-domain-containing-protein	unknown	unknown	gnl|CDD|350322
NZ_CP047147.1|WP_159312518.1|3255930_3256962_+|ABC-transporter	unknown	unknown	unknown
NZ_CP047147.1|WP_159312515.1|3253581_3253971_+|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224639
NZ_CP047147.1|WP_159312521.1|3264229_3265072_-|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|223669
NZ_CP047147.1|WP_008411241.1|3263770_3264139_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159312512.1|3250127_3250322_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_003949082.1|3261805_3262033_+|type-II-toxin-antitoxin-system-VapB-family-antitoxin	unknown	unknown	gnl|CDD|227737
NZ_CP047147.1|WP_159312519.1|3260711_3261710_+|CHAD-domain-containing-protein	unknown	unknown	gnl|CDD|377493
NZ_CP047147.1|WP_159312517.1|3255010_3255934_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|224054
NZ_CP047147.1|WP_018470082.1|3262491_3262950_+|DUF1992-domain-containing-protein	unknown	unknown	gnl|CDD|378159
NZ_CP047147.1|WP_159312522.1|3265167_3265641_-|DUF4440-domain-containing-protein	unknown	unknown	gnl|CDD|379275

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_003949082.1|3261805_3262033_+|type-II-toxin-antitoxin-system-VapB-family-antitoxin	gnl|CDD|227737	COG5450, COG5450, Transcription regulator of the Arc/MetJ class [Transcription].	4.83634e-05
NZ_CP047147.1|WP_159312520.1|3262029_3262437_+|PIN-domain-containing-protein	gnl|CDD|350322	cd18755, PIN_MtVapC3_VapC21-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC3, VapC21 and related proteins. This subfamily includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC3 and VapC21 toxins. It belongs to the VapC-like family of the PIN domain nuclease superfamily. VapC is a PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions; in some members, additional metal coordinating residues can be found while some others lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	6.33142e-60
NZ_CP047147.1|WP_008411243.1|3262971_3263670_-|type-1-glutamine-amidotransferase-domain-containing-protein	gnl|CDD|153235	cd03141, GATase1_Hsp31_like, Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Escherichia coli Hsp31 protein. Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Escherichia coli Hsp31 protein (EcHsp31). This group includes EcHsp31 and Saccharomyces cerevisiae Ydr533c protein. EcHsp31 has chaperone activity. Ydr533c is upregulated in response to various stress conditions along with the heat shock family. EcHsp31 coordinates a metal ion using a 2-His-1-carboxylate motif present in various ions that use iron as a cofactor such as Carboxypeptidase A. The catalytic triad typical of GATase1 domains is not conserved in this GATase1-like domain. However, in common with a typical GATase1 domain, a reactive Cys residue is found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow. For EcHsp31, this Cys together with a different His and, an Asp (rather than a Glu) residue form a different catalytic triad from the typical GATase1 domain. For Ydr533c a catalytic triad forms from the conserved Cys together with a different His and Glu from that of the typical GATase1domain. Ydr533c protein and EcHsp31 are homodimers.	4.39817e-98
NZ_CP047147.1|WP_159312514.1|3252203_3253478_+|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|227277	COG4941, COG4941, Predicted RNA polymerase sigma factor containing a TPR repeat domain [Transcription].	8.37414e-100
NZ_CP047147.1|WP_159312513.1|3251797_3252169_+|hypothetical-protein	gnl|CDD|226318	COG3795, COG3795, Uncharacterized protein conserved in bacteria [Function unknown].	2.20307e-17
NZ_CP047147.1|WP_010644928.1|3258517_3260728_+|RNA-degradosome-polyphosphate-kinase	gnl|CDD|235469	PRK05443, PRK05443, polyphosphate kinase; Provisional.	0
NZ_CP047147.1|WP_159312515.1|3253581_3253971_+|GntR-family-transcriptional-regulator	gnl|CDD|224639	COG1725, COG1725, Predicted transcriptional regulators [Transcription].	4.65372e-29
NZ_CP047147.1|WP_159312521.1|3264229_3265072_-|alpha/beta-fold-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.34649e-20
NZ_CP047147.1|WP_159312519.1|3260711_3261710_+|CHAD-domain-containing-protein	gnl|CDD|377493	pfam05235, CHAD, CHAD domain. The CHAD domain is an alpha-helical domain functionally associated with the pfam01928 domains. It has conserved histidines that may chelate metals.	4.96121e-06
NZ_CP047147.1|WP_159312517.1|3255010_3255934_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	2.89168e-66
NZ_CP047147.1|WP_018470082.1|3262491_3262950_+|DUF1992-domain-containing-protein	gnl|CDD|378159	pfam09350, DUF1992, Domain of unknown function (DUF1992). This family of proteins are functionally uncharacterized.	3.47702e-13
NZ_CP047147.1|WP_159312522.1|3265167_3265641_-|DUF4440-domain-containing-protein	gnl|CDD|379275	pfam13577, SnoaL_4, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	3.2064e-19

Protein sequences

>NZ_CP047147.1|WP_159312518.1|3255930_3256962_+|ABC-transporter
MTATLTPAGRADAPASAGRDRRAALPRAVLRLHRTALVVGAVLVGLFTLLLLGSLLWRSAYSPAEVAACGTGSGCPGLNAYETAHTVYWSLLNQSQNVLLLVPLVIAAYAAGPLTARERELGTHHLLWTQSAASPVRWLRSTLALGSVAVAVGAVFLVMVFRTAVAPMEGVWGFSGWEPGGYVGSGPVLVAYCLLGLAFGVCAGTLIGRALPAIFAGVAGTGVLLVAGTFGRPWLWPVSTVVTPFSEGRGAWPSPGTDWPKGAEVRGQWLVTGDGVRIDPASCTVPTGGIKECGVRAGVESWLVEFHPLSHRLPLQLVESGLVLLLAVLAAGAAFLVLRRRTP
>NZ_CP047147.1|WP_159312517.1|3255010_3255934_+|ATP-binding-cassette-domain-containing-protein
MTDTDTAIEARGLGKRFGRRNALDACSFRLPAGRICALVGPNGAGKSTLLTLAAGLARPSGGELRVLGTTPAEARREIAYVAQDKALFPQLTVADTLRLGADLNPGRWDQEAAERIVHGDGAESALDPYAKVRGLSGGQRTRVALALALGKRPALLLLDEPVSDLDPLARHQLMGTLLAEAAEHGTTVVMSSHILGELAGACDFLLLLGSGRVRMAGPADDLTAVHRLVTGPGGAAELAPHTVIESRPHGRGQSALIRPEGPVGPGWECEEPSLEDVLLAHLRNPSAPALLAPEATVRDLAETGVQA
>NZ_CP047147.1|WP_159312516.1|3253967_3254975_+|ABC-transporter
MSTTLNRSTGPGTSAPSSPSFRTLARVVLRLHRGALLTWVAVVVLVGAGLVWLRWVGVSVVLPGPLECWDGTGCGPQEVEADSGMWSIHVFWLGWISVLLTGLPVAVAAWAGAALTGAEQERGTAALAWTQSVSPRRWIAVKWAVAGGVLVTGVSVLVPLYVWARSVPFLTQSGTYDWADWVIFTASGPVTPALLLLALTLGAYAGLLLRRSLAALAVSAGTMFGAVQGLPQLIPYLWPAERAFGGLGEGVPSGAWRVSETALDAQGRPVPMGECLLDESAFRQCADAKGIEGVETLFHPASHAVPLHLAETALILALTAALAFAALRLLRRRTP
>NZ_CP047147.1|WP_159312515.1|3253581_3253971_+|GntR-family-transcriptional-regulator
MIAYRIDRRSGVATYLQIVQQTRQALRLGLLEPGDKLPTAREVVEATAVNPNTVLKAYRELEREGLVEARRGLGTFVRRTLEPDADTGPLQAELAEWAARARKAGLGREDVAALCTAVLDSTYPEGEDR
>NZ_CP047147.1|WP_159312514.1|3252203_3253478_+|sigma-70-family-RNA-polymerase-sigma-factor
MRRPPPGAGVEHLLRTEAPQVLGALTRRFGRFDIAEDAVQEALIVAGQRWPAEGVPQDPRSWLIRVGYRRMVDLLRAEQARHRREQEVGRTELALGTPERRAAPTGSTDDSLTLLLLCCHPRLSPVSQVALTLRAVGGLTTAEIARAYGTSEATMGTRISRAKQQLVRDGARFVPATDPDRRERTEAVMRVLYLIFNEGYTASSGESLARRDLSEEAVRLARLLHAADPDNAEAAGLLALMLLIESRHSARTDADGALVPLESQDRTRWDQELIREGTRLLDAVWDPRGTGTGPYQFQAAIAALHAEAPAPELTDWPRIAMLYLWLERLTPTAPVRLSRVVAVARAFGPTRGLTLLDTLCRRHSLDRDPLVRHHERAVRAHLTRMTGDTAGAAALYREAATLTANGAERRYLLTEAERADGTAT
>NZ_CP047147.1|WP_159312513.1|3251797_3252169_+|hypothetical-protein
MKYLLLGYTSADGWDASTAGSPTEEALEAFAAYQRFEEELTASGELVSTEGLGHPAVSTTVRPTAEGVTATDGPFAELKEVLASFAVIDVSGQERAVEIAARIVAVLGEPVEIRPVMGADFAA
>NZ_CP047147.1|WP_030765598.1|3251133_3251577_-|hypothetical-protein
MSETETETAPQQPTPELRALDRLTGNWKVTGGAEGTVRYEWMAGGFFLLQHVDLVQFGQPVTGMEIIGNLRPFGEPTGPDVASRYYDSQGNTFDYVYELDGDTLTIWAGAKDSPAYFRGTFTPDGTTMTGDWIYPGGGGYSSTMTRV
>NZ_CP047147.1|WP_018470074.1|3250506_3250881_+|hypothetical-protein
MTAGAVEYLAETYGGDARSSVFLGGIITPTRRLALRWLRGQARRIADALDPYPYVRWAPPGALRRVPAADRDAPGALRGWQASTACQDAALHALAAGGPFAFLTHDATCWYRLTVHPLPGPVTP
>NZ_CP047147.1|WP_100458188.1|3250297_3250510_+|hypothetical-protein
MRGGAVGVMGAEARDGEAEFNPLLFPPCACPRHRGAEGEAGEGEESAVLRQLRARVAEENGARRWVRGQG
>NZ_CP047147.1|WP_159312512.1|3250127_3250322_+|hypothetical-protein
MTHEQQPAQASAAPEEATLCRPCQELALAEAVAKAEYDWSRATDCRVLMKRHRESGECVAGQSV
>NZ_CP047147.1|WP_018470081.1|3257710_3258151_-|hypothetical-protein
MKKLAKFSLLTGGALLFSSLAVGPASAATAYGSCATSPLSSSGSVNIANWPYSGKVTGINLRLYDEKPDGHHVRIRLAERWTTGKMVYYAWRKNMDGYGTYKSWDTYMNPTGANNKISGIVLQVATFEGETQLQFCEKRLYNPGGA
>NZ_CP047147.1|WP_010644928.1|3258517_3260728_+|RNA-degradosome-polyphosphate-kinase
MLRTPGETPDPLEQGPQPPLASLTSAHRAQPAADLDSDPDDYPGDDEAELPEGRFLDRERSWLAFNERVLELAEDPYTPLLERANFLAIFASNLDEFFMVRVAGLKRRIATGVATKSASGLQPREVLEMIWARSRELMARHAACYQQDIAPALADEGIHLVRWAELTEEEQARLFTLFRQQIFPVLTPLAVDPAHPFPYISGLSLNLAVVVRNPVSGHRHFARVKVPPLLSRFLEASPERYVPIEDVIAAHLEELFPGMEVLAHHMFRLTRNEDLEVEEDDTENLLQALEKELMRRRFGPPVRLEVEESIDPYVLDLLVRELKISDAEVYPLPGPLDLTGLFGIAGLDRPELKYKKFVARTHRDLAEVESASAPDIFAAVRERDVLLHHPYDSFSTSVQAFLEQAAADPDVLAIKQTLYRTSGDSPIVDALIDAAESGKQVLVLVEIKARFDEQANIKWARKLEESGCHVVYGLVGLKTHCKLSLVVRQEGELLRRYSHVGTGNYHPKTARLYEDLGLLTVDPKVGADLSDLFNRLSGYSRRESYRRLLVAPHSLRAGLVARIHQEIEHHRAGREAYVRIKVNSMVDEAVIDALYRASMAGVPVDVWVRGICALRPGVPGLSENIRVRSVLGRFLEHSRVFVFGNGDEPEVWFGSADMMHRNLDRRIEALVRVTDPAHRATLDRLLETGVADTTSSWHLDADGEWTRHSHDAEGKPLRHVQEMLIDARRRRRAPTP
>NZ_CP047147.1|WP_159312519.1|3260711_3261710_+|CHAD-domain-containing-protein
MPRLPEPDHLPEQAAGPAPAAAPVATALRAEAAAFLRALRHHTEAAQDPQEAREAARSLGRSARRLGATLHTFRPLLDREWADRLRPELTWLSGVLADEHLVAARLTRLLASLHRLSGPAAPRRGGPGIGAAKAGALLERRLTLARTRAHSACLTAFASARLHALVDEVALLGGDVPLAEDAHLRPAGRADTLAEAAARRLSDAVTALPLHRAGHPYNADALALAVPAPDGQDSPWHQVRLLLRLHRYAQEVVAPDAAPDPRVTAARHALDHHRDASEAAHEAASAAATPRIAPTTAYALGVLHADQRHEVEAARYAFQRAWAGEAVGVGGE
>NZ_CP047147.1|WP_003949082.1|3261805_3262033_+|type-II-toxin-antitoxin-system-VapB-family-antitoxin
MSRTVIDLDDDALAAAAQELGTRTKRDTVNAALREVVERNARLRALHELQELTAEGALDIEVLLDKSARRGGIGR
>NZ_CP047147.1|WP_159312520.1|3262029_3262437_+|PIN-domain-containing-protein
MSVPDYLIDTSALVRVLQRRVPREWEHRIGAGLVSLCDLTEIELLYSARSTSDRDAIRDRLSLFTWCPMPDGVFRRARTVQALLTDKGEHRSAGAVDLLLAATAEQSGLTLLHHDRDFETVARATGQPVRMIDLR
>NZ_CP047147.1|WP_018470082.1|3262491_3262950_+|DUF1992-domain-containing-protein
MTERKPADVSHEDWVEHQIRQAERRGEFAELPGRGKPLPGNEVEYDALWWVKAKMRREGLGQERPADGAGSLVAVCRRDAEELPAVLARIEDEAEVRRRVGELNKRITDLHLMPPPGPPLGIPRFKVDEVVREWRRARQLAARGRPGGTGRG
>NZ_CP047147.1|WP_008411243.1|3262971_3263670_-|type-1-glutamine-amidotransferase-domain-containing-protein
MATPTNRILIIVTSAGEYESAGYRTGLWLGELTHFYDVAEAAGFGLTIASVDGGRVPIDPESLAHDVLADQGTAERYADRTFMNLLEDTVAVADVRPEEYDAIYLTGGHGTMFDFPRSKALGELVAAFHDEGRVVSAVCHGPCGLLETTLADGRPLLRGREVTGFSWPEEELAQRADAVPFSLEERLRALGASYSVAEEPFAPYVVEDGLLITGQNPASATPVAEAVVRALR
>NZ_CP047147.1|WP_008411241.1|3263770_3264139_-|hypothetical-protein
MSGWMWWGLAFMLLGGGSWIGESVRSALKARHTRKLELQRAETERQRALDAANRPPEPICGCTHHLAKHDKQGTCHERVQAPVEWDADRKPVKFEERPCNCQQYVGPEPLGTVYAPEITDRG
>NZ_CP047147.1|WP_159312521.1|3264229_3265072_-|alpha/beta-fold-hydrolase
MPQLELSAGVVDYEDTGGDGPVVVLLHGVAMDASLWDEVVPGLSGEYRCVRPVLPLGGHRRPMRAGADLSVPGVARLVAEVLERLDLRRVTLVLNDWGGAQALFALGLGERIGRLVLTSCEAFDNYPPGLPGRNLVTAARLPGGLAAAFGLLRLRPARRLPMTWGRMSLRPVPARLMDGWLRPAQTSPEIRRDLRAYLLGVPPREELLRWTEALREFEGPALVAWAAEDKVMPVEHGRRLAALLPRAAYVEIAGSRTLIPVDQPAELLAHLRDFLARTDC
>NZ_CP047147.1|WP_159312522.1|3265167_3265641_-|DUF4440-domain-containing-protein
MDTDLTDPVERMLAERACERLVVEFGQRLDLGDPGDVAELFTEDAVWEWPAGERRIEGREALRAYFAGRPADRLSRRVASNILVTVTSPDTATATSYFTTYRVDGHTGGPVPARPPAQVGHYEDTFHRAGGRWRLARRTLFLAFAGPTDRLPAVGRD

Crispr_ID: NZ_CP047147_15

• CRISPR_ID: NZ_CP047147_15
• CRISPR_location: 3402255-3402353
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP047147_15

Consensus_repeat	Method
GCCAGGAGGCAGAGGTTGGCGCCCTGG	CRISPRCasFinder

spacers of NZ_CP047147_15

>15.1|3402282|45|NZ_CP047147|CRISPRCasFinder
GTGTTGGTGACCCGGGCCGGGTCGTTCGTGCCGGTCGTGCAGTGG

CRISPR arrays and Neighbor proteins around NZ_CP047147_15

CRISPR arrays

The CRISPR arrays of NZ_CP047147_15

>merge|NZ_CP047147|15|3402255-3402353|CRISPRCasFinder
GCCAGGAGGCAGAGGTTGGCGCCCTGGGTGTTGGTGACCCGGGCCGGGTCGTTCGTGCCGGTCGTGCAGTGGGCCAGGAGGCAGAGGTTGGCGCCCTGG

>NZ_CP047147|15|14|3402255-3402353|CRISPRCasFinder
GCCAGGAGGCAGAGGTTGGCGCCCTGG	GTGTTGGTGACCCGGGCCGGGTCGTTCGTGCCGGTCGTGCAGTGG
GCCAGGAGGCAGAGGTTGGCGCCCTGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_159312581.1|3398509_3399199_+|pyridoxamine-5'-phosphate-oxidase-family-protein	unknown	unknown	gnl|CDD|274926
NZ_CP047147.1|WP_159312584.1|3402807_3413106_+|amino-acid-adenylation-domain-containing-protein	unknown	unknown	gnl|CDD|237108
NZ_CP047147.1|WP_159312587.1|3419489_3420158_+|DUF998-domain-containing-protein	unknown	unknown	gnl|CDD|377627
NZ_CP047147.1|WP_159312582.1|3399379_3400609_+|hypothetical-protein	unknown	unknown	gnl|CDD|226614
NZ_CP047147.1|WP_008408883.1|3390357_3391392_-|iron-siderophore-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|238566
NZ_CP047147.1|WP_030771211.1|3413198_3413408_+|MbtH-family-protein	unknown	unknown	gnl|CDD|377081
NZ_CP047147.1|WP_008408879.1|3395111_3395909_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224045
NZ_CP047147.1|WP_159312579.1|3395978_3397112_-|iron-chelate-uptake-ABC-transporter-family-permease-subunit	unknown	unknown	gnl|CDD|227119
NZ_CP047147.1|WP_008410714.1|3415336_3416035_-|histidine-kinase	unknown	unknown	gnl|CDD|379374
NZ_CP047147.1|WP_030765879.1|3401743_3402142_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_010644708.1|3413404_3414427_+|daunorubicin-resistance-protein-DrrA-family-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|130256
NZ_CP047147.1|WP_159312586.1|3417861_3419106_-|MFS-transporter	unknown	unknown	gnl|CDD|225371
NZ_CP047147.1|WP_003949226.1|3400586_3400952_-|PH-domain-containing-protein	unknown	unknown	gnl|CDD|377953
NZ_CP047147.1|WP_159312580.1|3397108_3398263_-|iron-chelate-uptake-ABC-transporter-family-permease-subunit	unknown	unknown	gnl|CDD|182464
NZ_CP047147.1|WP_159312583.1|3401088_3401442_-|PRC-barrel-domain-containing-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159313910.1|3391670_3394997_+|S8-family-serine-peptidase	unknown	unknown	gnl|CDD|173800
NZ_CP047147.1|WP_061404637.1|3414414_3415215_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|366444
NZ_CP047147.1|WP_030771201.1|3417385_3417847_+|DUF2269-family-protein	unknown	unknown	gnl|CDD|370783
NZ_CP047147.1|WP_003949238.1|3416901_3417255_-|PadR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|163261
NZ_CP047147.1|WP_159312585.1|3416206_3416905_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_159312581.1|3398509_3399199_+|pyridoxamine-5'-phosphate-oxidase-family-protein	gnl|CDD|274926	TIGR04025, hypothetical_protein, PPOX class probable FMN-dependent enzyme, DR_2398 family. Members of the PPOX family (see pfam01243) may contain either FMN or F420 as cofactor. This subfamily consists of proteins mostly from species that lack the capability to synthesize F420, and therefore most likely all bind FMN.	4.67709e-79
NZ_CP047147.1|WP_159312587.1|3419489_3420158_+|DUF998-domain-containing-protein	gnl|CDD|377627	pfam06197, DUF998, Protein of unknown function (DUF998). Family of conserved archaeal proteins.	1.97043e-08
NZ_CP047147.1|WP_159312582.1|3399379_3400609_+|hypothetical-protein	gnl|CDD|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	6.16903e-12
NZ_CP047147.1|WP_008408883.1|3390357_3391392_-|iron-siderophore-ABC-transporter-substrate-binding-protein	gnl|CDD|238566	cd01146, FhuD, Fe3+-siderophore binding domain FhuD. These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. A typical TroA-like protein is comprised of two globular subdomains connected by a long alpha helix and binds its specific ligands in the cleft between these domains.	5.07307e-63
NZ_CP047147.1|WP_030771211.1|3413198_3413408_+|MbtH-family-protein	gnl|CDD|377081	pfam03621, MbtH, MbtH-like protein. This domain is found in the MbtH protein as well as at the N-terminus of the antibiotic synthesis protein NIKP1. MbtH and its homologs were first noted in gene clusters involved in non-ribosomal peptides and other secondary metabolites by Quadri et al. This domain is about 70 amino acids long and contains 3 fully conserved tryptophan residues. The structure of the PA2412 protein shows it adopts a beta-beta-beta-alpha-alpha topology with the short C-terminal helix forming the tip of an overall arrowhead shape. MbtH proteins have been shown to be required for the synthesis of antibiotics, siderophores and glycopeptidolipids.	2.14237e-27
NZ_CP047147.1|WP_008408879.1|3395111_3395909_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224045	COG1120, FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism].	8.33355e-135
NZ_CP047147.1|WP_159312579.1|3395978_3397112_-|iron-chelate-uptake-ABC-transporter-family-permease-subunit	gnl|CDD|227119	COG4779, FepG, ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism].	2.93264e-77
NZ_CP047147.1|WP_008410714.1|3415336_3416035_-|histidine-kinase	gnl|CDD|379374	pfam13796, Sensor, Putative sensor. This family is often found at the N-terminus of proteins containing pfam07730 and pfam02518. The N-termini of proteins containing these two domains often function in stimulus sensing.	3.45454e-26
NZ_CP047147.1|WP_159312584.1|3402807_3413106_+|amino-acid-adenylation-domain-containing-protein	gnl|CDD|237108	PRK12467, PRK12467, peptide synthase; Provisional.	0
NZ_CP047147.1|WP_010644708.1|3413404_3414427_+|daunorubicin-resistance-protein-DrrA-family-ABC-transporter-ATP-binding-protein	gnl|CDD|130256	TIGR01188, drrA, daunorubicin resistance ABC transporter ATP-binding subunit. This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other].	1.12447e-114
NZ_CP047147.1|WP_003949226.1|3400586_3400952_-|PH-domain-containing-protein	gnl|CDD|377953	pfam08000, bPH_1, Bacterial PH domain. This family contains many bacterial hypothetical proteins. The structures of Structure 3hsa and Structure 3dcx show similarities to the PH or pleckstrin homology domain. First evidence of PH-like domains in bacteria suggests role in cell envelope stress response.	4.12332e-63
NZ_CP047147.1|WP_159312580.1|3397108_3398263_-|iron-chelate-uptake-ABC-transporter-family-permease-subunit	gnl|CDD|182464	PRK10441, PRK10441, Fe(3+)-siderophore ABC transporter permease.	1.22195e-89
NZ_CP047147.1|WP_030771201.1|3417385_3417847_+|DUF2269-family-protein	gnl|CDD|370783	pfam10027, DUF2269, Predicted integral membrane protein (DUF2269). Members of this family of bacterial hypothetical integral membrane proteins have no known function.	0.00200565
NZ_CP047147.1|WP_159313910.1|3391670_3394997_+|S8-family-serine-peptidase	gnl|CDD|173800	cd07474, Peptidases_S8_subtilisin_Vpr-like, Peptidase S8 family domain in Vpr-like proteins. The maturation of the peptide antibiotic (lantibiotic) subtilin in Bacillus subtilis ATCC 6633 includes posttranslational modifications of the propeptide and proteolytic cleavage of the leader peptide. Vpr was identified as one of the proteases, along with WprA, that are capable of processing subtilin. Asp, Ser, His triadPeptidases S8 or Subtilases are a serine endo- and exo-peptidase clan. They have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The stability of subtilases may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	1.0932e-80
NZ_CP047147.1|WP_061404637.1|3414414_3415215_+|ABC-transporter-permease	gnl|CDD|366444	pfam01061, ABC2_membrane, ABC-2 type transporter.	4.13339e-20
NZ_CP047147.1|WP_159312586.1|3417861_3419106_-|MFS-transporter	gnl|CDD|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	1.62207e-86
NZ_CP047147.1|WP_003949238.1|3416901_3417255_-|PadR-family-transcriptional-regulator	gnl|CDD|163261	TIGR03433, padR_acidobact, transcriptional regulator, Acidobacterial, PadR-family. Members of this protein family are putative transcriptional regulators of the PadR family, as found in species of the Acidobacteria. This family of proteins has expanded greatly in this lineage, and where it regularly is found in the vicinity of a putative transporter protein [Regulatory functions, DNA interactions].	8.53379e-30

Protein sequences

>NZ_CP047147.1|WP_030765879.1|3401743_3402142_+|hypothetical-protein
MTKHQAARILIGAGAAFGLVLGATGAANAAPSNPIKTQGGYAQWNADPSGSIPGDSIRACDNTADGWGIEAWLDINRDGTIDRIASTRGHNAPYCTSWKSGDIPEGTPVTVYAVTVNGGIVLEKGGALWSKA
>NZ_CP047147.1|WP_159312583.1|3401088_3401442_-|PRC-barrel-domain-containing-protein
MSDGIWGYQPTAGHTAGADLIGYKVEATDGTIGKVDKHSDEVGSAYLVVDTGVWIFGKHVMLPAGTVRTVDSAERKIHVELTKEQIKNSPEFDKDRHAGDAQYHDQLGGYYGGHRPL
>NZ_CP047147.1|WP_003949226.1|3400586_3400952_-|PH-domain-containing-protein
MALFGNAHTVDPGSAQQEYARLLGQGEQVHAAYLLIRDTILFTDRRLILVDKQGITGKKVEYHSIPYRSITHFAVETAGTFDLDAELKIWLSGATTPVQKTFTKGVDIYEVQAILTQFVTR
>NZ_CP047147.1|WP_159312582.1|3399379_3400609_+|hypothetical-protein
MSDTATRGKGERVADWGRRLRRPESSARRSLLLILKSALAATVSWFVSYELMNATSPAFAPFSAVLMVQVTVYQSVVQSLRYVGAVAAGVAVQAVLGLSAGPDLVTFALVALVALVISRWRLLGAQGSQVATAAFFAFATYTGASSDTDQVKELGQIVLLVLIGSAVGVGVNVLIAPPLRYRSAEWGIRALAQEIHDLLDTMAPELGEGAPDADTTQGWRDRADRTGTLISQSREGLRTARESLRLNPHPWARRRRGTLTFEAYDRTMEALVRMISQVTAITRSLDLQHQDEKQQQEEESGPDRDYAPFLRAYATFLSSVVDFTEILATLDEDHLRDQAGRLDEAADGLERCRREVVRTTEDRGLSLTDPTEPYGVLVVEATRLSEECRYTAGVLGNSAENGSSGSRTA
>NZ_CP047147.1|WP_159312581.1|3398509_3399199_+|pyridoxamine-5'-phosphate-oxidase-family-protein
MTNPAPEAPATGLHHSLARLTRVPDARGLGLTEPAVPAAPLVPEAPATSPLPAGYTELTGVEELDALLGVPHPIVIDKVHDRLDAQDLDLLSRSSFCSLSTADAEGNCDVSPRGGVPGFTHVVDPGTLALPDRPGNRRGDSFRNILTNPHVGLLYLIPGVMDVLRINGRARILTDAPFFDALVEKNQRPKLALVVEIDEIYRHCPASLRRSGIWSPDTWENAAGGTSPA
>NZ_CP047147.1|WP_159312580.1|3397108_3398263_-|iron-chelate-uptake-ABC-transporter-family-permease-subunit
MNGPADREGRPADPSGTPPSRTRSTALLDLGKRPDAEGATAITAPPPRRSVRSRPALAAGLFLALVGLGLTLVASLAVGSGDVPFADVLGTFLDPDAENKAQLIVGEVRIPRTVAGLLSGVALGLAGTVMQGVTRNPIADPSLLGINAGASLSVVFAISVLGLGASQQYLWFGFLGALIAALVVYGVGSLGREGATPVKLALAGAATTAVLTSLTTTMLLTDRQSYDQFRFWQIGALNTRSVEVLSEAAPFIVVGGLLALTLGSQLNALALGDDLARGFGQRVGLVRGVSAVAVVLLCGASTVVAGPIGFVGLAVPHIARLVTGPDYRWVLPYSMVLAPMLLLWADIVGRVVAQPGEVQVGVVTAALGCVPFIWLVRRRKLVEL
>NZ_CP047147.1|WP_159312579.1|3395978_3397112_-|iron-chelate-uptake-ABC-transporter-family-permease-subunit
MSDRATSSFEKADAEKAAPARTDTSPLHVSEAVLAEAARTVAGARRRGGRRSVLVGLVLALAAFAVFAVSLSVGDMVIPLADVLATLFGGGDAGAQFVVLELRLPRALLAVLVGAGFGMAGAVFQTVLRNPLASPDVIGISSGASAAAVTASMVFAVSGLALSASALIGALIAGTLIYLLAWRKGVVGARLVLVGLGVGFGLNSLVWYLMSRAEVSNAQNALLWLTGSLNGRSWNQVWPQLIALAVLVPLTFAAARALPALQLGDDTASGLGARAERNRLALLACGVALAGVSTAAAGPVAFVAFVAAPVARMLLPGRGAVLPHAALAGALLVLLADFAAQHALPGTQLPVGVVTSVVGAPYLLWLLARANRVGRGG
>NZ_CP047147.1|WP_008408879.1|3395111_3395909_-|ABC-transporter-ATP-binding-protein
MSAEHTLEARDVRIGYDGREIVPGLSVKIPPGRFTVIVGPNACGKSTLLRAMARLLAPTSGAVLLDGRPVQQTPTREVASVLGILPQSPVAPEGITVSDLVARGRYPHQGWFRRWTAEDDAAVGAALLSTDVLDLAERPVDELSGGQRQRVWIAMALAQRTDILLLDEPTTFLDVAHQMDVLDLLTDLNRERGVTLVAVLHELNMACRYADHLIAMKQGEVVAEGAPSDIVTEQLVSDVFGMRCSVVPDPASGTPLVVPLGRHHV
>NZ_CP047147.1|WP_159313910.1|3391670_3394997_+|S8-family-serine-peptidase
MVAAAVAVALAAGTAPSAVAQPDPRGTSGDRAHAPDRVKRHLTLVTGDRVGLDADGTPVTFRPAKGRERIPVKRMSDRGHTLVVPADAHRLVVSGKLDRRLFDITELSRPENLRAQRDGLKLIVGYRGKQAHAAKAQVREAGGTEVGRSLTSLNAESVTTPAGDVPEIWKALTAGPGDGERVTTAAGIDRVWLDGVRRASLDKSVPQIGAPTAWKAGFTGKGVKIAVLDTGTDTTHPDLKGQVLAEKNFSSAEDTVDRVGHGTHVASIAAGTGAASGGAFKGVAPDAKLLAGKVLDDDGYGEDSGILAGMEWAVAQGADIVNLSLGGTDTPEVDPLEAAVDKLSAEKGVLFAIAAGNEGDGAGTVGSPGSADAALTVGAVDDKDELADFSSRGPRVGDGAVKPDVTAPGVDTTAAIPSDSLIAQEVGENPAGYATISGTSMATPHVAGAAALLKQQHPKWSYAELKGALTASAQPGPYNPFQQGSGRIAVDRALKQTVVADPVSVSFGVQQWPHTDDEPVTEQVRYRNTGTADVTLDLKVTGTGPKGKPAPAGFFTLGADRVTVPAGGTAEVALTADTRLGGDADGTYAAYLVATGGGQTVRTAAAVEREVESYDLTVKHLGRDGRPAAQAETTVFRFDAGADFPFLDPQVVDGTAKIRVPKGTYVVDSNVYQDPEDVTKGVDWIAQPKVAVTKDTTLTFDARKAKPVKITVPDSKAESQIFSPDYGVETEDDAVTFGWVADSPAGMRTLHVGPKITDGSLTQHWSGTWTRGATTQFDIAVGGKVERLATGYSRKFTTGQLAKVKLAMGAAAPKKKGEVTAWPLLPSQNSGWVVSGEQKLPGTRTLYLSTADQVRWDMDFSQLGDLDEEGFPAYETGYQVAAGAVFRPGWTYRKSVNTAVFGPLVNKEFGVFRDGNEIGGYLPLLADGRGNPGGIELSKATSVLYRNGKETGRNSDPLAGEEVFRVPAAAADYRLKATVRHSAKISPLSTRVDVDWTFRSKKTGDHTPLPVSTVRFSPEVAADGTAKAGKTVSVPVKVQGAAAGKNLKSLTTYVSHDGGKNWKKVPVKKGKITVKNPAKGKAVSFAAKVTDKKGNTSKVRIYSAYLGK
>NZ_CP047147.1|WP_008408883.1|3390357_3391392_-|iron-siderophore-ABC-transporter-substrate-binding-protein
MNDSAFSGKAARSSRRRKTATLAGAVAALLVGLTACGAGGDEQAEKPAEGKASSGAFPAKVATKFGEITIDEAPKRIVALGWGDAETALALGAQPVGASDWLPFGGEGVGPWAKGMYDKKPELIGTMEPEFEKIAALKPDLILDTKSSGDQTRYDTLSKIAPTVGVPKGGDMYMTSWEKQTEMVAGALGKKDEGAELIADTEKKFAAAAKEHPEFKDKTITVGSRTSEGFGAYVGGTGRVDFVKRLGFVNNPEIEKLAGDSFSVSVSKEKLDLLDADLTVMAPIGISAKEISDDPLYKAVPSVKDGRSIVFDDKDISQAFATDSVLSVGYALDKVVPLFSEKLK
>NZ_CP047147.1|WP_159312584.1|3402807_3413106_+|amino-acid-adenylation-domain-containing-protein
MPSVPSDRPSAAFPLTAAQRGLWFAQRLDPDSPAYNVAEYVEVRGELDVRALRRAVRHVEEETEALRLTFGERDGVPWQRVRAEAGIEVPVSDVSGYADPHAEAVRRMTAELARPADLARGPLVRMALYRLAEGHHLFHQQVHHLAVDGYGAVLALARIAEVYTLLVTAPGEPVPVRPAPLGPVLADEEAYGNSEQRSRDGEFWAAYLDGAPAPAGLVPGAPGAPGGPARRVRAVSRRLGAEETAGLRAAAKRAGVAWPAFLMAALGVCLHRERGLGEVVLGLPVTGRRTPAARTTPAMLSQVLPMRLAVSPADRVADVARRASAEARQVLRHQRYPAQELRRERGLGVREAQAGPAVNVLAFDDTLSFGPSPATLHNLSVGPVEDLAVAAHASYGDGGLSLDLLGDADRYDEAGLARHHEAFCRMLAAFAEDPERPLGALPLVPAPEHARLVRLGTGPVAEGGPLPTLPEQFAAQAARTPWATAVVCGDERLTFAELDARVRALSVELAARGARPGERVAVGLERSADLVTALLAVLRSGAAYLPVDPSYPVDRLAYMLQDAAPVALVARPGTAVPHEGLELVDPAAVVPGGDGGVPEPPVPEPHDAAYVIYTSGSTGRPKGVVVEHRSLAQLLEHHRREAHALAAESLGRRLRVALTAAISFDASWDPVLWMLAGHELHLADDATRRDPEALAAFLTARRIDAVETTPSHLRQLLAAGLLAGDGHHPRVLALGGEPVDDALWAELRDHDELIVLNYYGPTETTVDAVTARVTGTAPAIGRPVAGARAYVLDSALHPMPLGTPGELYLSGEGVARGYAGRPGLTARRFLPDPYGPPGARMYRTGDLARWRPEGTLEFLGRTDDQVKIRGHRVETGEVEAALRALPGIADAAVAPAGPAGGERRLAAYLVPGPGGTDPAEVRDLLTAALPDHLVPALYAVLDRLPLTPNGKLDTARLPEATAPRSAGGAPRTEDEERMCAEFAACLGLDAVGRDDDFFRLGGHSLLATRLIGRVREAFGAEVAIRALFDHPTPAGLLTALDRTAPALPPLRAARPRPARVPLSPAQRRLWLLERLGGAGTAYHLPVGLRLSGPLDRDALAAALGDVAERHESLRTVVAEDADGPYQRVREPAPVPLAVAQLPRTGSPAPDPEPFDLAGEPPMRARLFTDGDRGHLLVLTFHHIAADGWSMLPLLGDLGDAYAARRAGRAPGLTPLPVQYADYALWQRELLGTPDAPTGRAARQLAHWRAALDGAPAESAPPADRPRPDRPSGRGGAVPVTVPAAVHRALLERAAASGTSPFMVLHAALAALLSRLGAGDDLVVGTPVAGRPDEVLAGLVGFFVNTLALRTDTSGDPDLTTLLARVREADLAALAHQELPFEQVVSAVSPPRHPARHPLFQVMLALDNTPAPRAALDGLTVRRDTATGRTGAKFDLTWDLAERHTADGAPAGIGGELEYSEDLFDQATAERYAAQFTTLLTALLDRPDTPFTDLPFLGARDRAAALDENGPTRPPATPDWTLTDVLATRAAADPGRTAVVDATGRLTFGELQDRAERLARRLAAAGVRPGDRVALALPRSAATLAALLGVLRAGAVHVPLDTTHPPARNTLVLRTAAPRLVLTTATTDEAVPATGHPRLVLAEDPDDWPATGPLPAPPRPEDAAYVLYTSGSTGRPKGVVVDHRALAHLYAHHREHLIGPAQAAAGGRQLRVALTAALTFDASWDPVLWMAAGHELHLVDDATRRDPEALTAHLRERAVDVVETTPSFAELLRSCGLFAPGHHRPRVLALGGEAVTEPLWEELAALPDVTAWNLYGPTEATVDALVAPVTAGTRPHLGRALPGARARVLDARLAPAAPGATGELYLTGPGLALGYERAPAATAARFLPDPYGPPGSRMYRTGDLVRRRAGRLEYLGRADGQAKVRGFRVETGEVEAALLRHPGVALAAATVRPGPDGSGRLLAWAVPAEGHRPTGRELRAHVATRLPSYMVPAAVVPVATLPLTVHGKTDFAALPDAPGPEAPADGTAVPRSAREEILCALFAECLGQPHVTRDDDFFALGGHSLLALGLIGRVRSAFGVELSVRTLFDATTPAALAARLDAAQPARPALRRAERPARPPLSPAQRRLWFLHGLDPADASYHIPVAVRLDGRLDRAALRDALADVTARHESLRTRVQDHEGEPCQAVLDPADARPALPTTPVTEAEVEAALREAAALPFDLAADLPLRAELFALGAERHVLLVTVHHIAADGWSMGPLAEDLAGAYAARTAGRVPQWAPLPVQYTDYTLWQADLLGDPDDAKSVAGRQLAYWAEQLRGTPDEVPLPADRPRPARATGRGGTVDLTLPPATTEAVTRLARATGTSPFMVLHAALAALLTRTGAGEDLTVGTPVAGRTDEALHPLVGFFVNTLPLRVSTGGDPTFRTLLARVKETDLAAYAHQDLPFERLVEEVRPARSLNRHPLFQTMLTLNNTRPPRLDLPHLAATLDGVASGGAKFDLSFSLREEDGTLTGTLEYSADRFEPGTARRIAAWFAHLTAAATAAPDTPVRQLSLHGPEEEERLLALGRGEPGEPVTGTVLDRFAATVAGARHGEPAVTAPDGTLTFAELDARARHVAALTASAGVVPGDRVAVLLPRSADSVAALLGVLTAGAVHVPLDPALPEARLAAVLADARPRLALATTATAPLLPAGQPRLLLDQAPPAASAPTTPRPTPDDPAYLLHTSGSTGTPKGVLVGHRSLARLLDHHRRHLFAPAVRATGRARLAVALTAALTFDAAWDPLLWLLDGHHLHLVDDQVRRDPEALVDAVRTHRLDVLETTPSHTAHLLDAGLLADGAHHPAVLALGGEAVPAPLWTRLRAAPATRCLNLYGPTEATVDTLTADLADTPHPVLGTPVTGTRAHVLDAALRPTPPGVPGDLHLAGDSLALGYPGRPAETAARFVPDPYGPPGSRMYRTGDRAVRNADGSLVFAGRADGQVKIRGFRVETGEVAAVLEAHPQIAHAAVVPHEDPEAGTTLTAHLVPAPGTDPNPEEIRAHAARHLPAYMVPTGWSTLDRLPLTAHGKLDTAALPVPRALAVPTGGRVPRTPREDVLCTLFAEALGAERVTIDDDFFALGGHSLLATRLIGRIRATLGTDLSIRTLFEAPTVAALAGRLDSAADDDSLATLLPLRTTGSLPPLFCVHPAGGLAWPYAGLLPHLDPGQPLYGLQTPNLDGTAPFPESIEEMAATYAAEIRAVQPHGPYRLLGWSFGGNVVQEIAVQLQEAGEEVALLAILDAFPLAPRDDLDSAPRDAVFRALLANLGVGEEAAEGSGGVDAAAVREEFRRAGSPLGALEPATIDAMVDNFAGQARLMRRYTPRTFHGPVLFFTATEGRPADAFPHALWDPYLTGPLHDTPVACAHAQLMSPDARATVGPVLAEALAALAEPEATPPAP
>NZ_CP047147.1|WP_030771211.1|3413198_3413408_+|MbtH-family-protein
MTNPFDDPRTHHRVLVNDEGQHALWPSFATVPAGWEAVFGPADQDACHAYVEEHWTDLTPRSARRTVAA
>NZ_CP047147.1|WP_010644708.1|3413404_3414427_+|daunorubicin-resistance-protein-DrrA-family-ABC-transporter-ATP-binding-protein
MSRARPAPPGDGPALRAEGLTKRFGTKQALAGVDLDAPAGTVLGLLGPNGAGKTTTVRVLTTLLRPDTGRAWVAGHDVRTAPEAVRARLGLSGQYAAVDEKLTGRENLYLVARLYGTGRGPARRRAAELLDRFRLSEAADRPSGTYSGGMRRRLDLAGALVARPAVVVLDEPTTGLDPRGRADTWECVRELVATGTTVLLTTQYLEEADQLADSVAVIDHGRVIAQGTAAALKSRVGGERLTLTLPDPASRPGALDLLAPLTPHRPHLDPRTGVLTLPTDHGPATLEQALAALRHAGVPLGEVSLAPPTLDDVFLALTGQETSTAPAPGPVPTKEPAWQP
>NZ_CP047147.1|WP_061404637.1|3414414_3415215_+|ABC-transporter-permease
MAAVTRLARDATLIAWRNLLNLRRTPGSVVAALIQPVMFVLLLSYVFGGSLGGDAYRTYLMGGIFAQAVTFNAAFTALGLANDLDRGIVDRFRSLPMPPMAVILGRTLSDLTMSALTVAVTSLCGLFIGWRIAGTLPEAVLAYLLILLFAFAMSWVGATIGLTARSVEVAQSAGLIWLFPVTFLSSAFVPTATLPTALQPVADWNPVSATATALRTLFANPAPPTAPLRDTWPVTHALPYALLSTLAITAVFMGVAVRRFRAMGRG
>NZ_CP047147.1|WP_008410714.1|3415336_3416035_-|histidine-kinase
MATADIPTADIPTACPLPHVSEQPAGAVRRGPLSAAAWREYGYVFTSFPLAIAGFVLAVTLFSLGAGLAVTVVGFPVLVALLAGARGLGAGERGRASGLLGLRTKEPAPVPAGGIKGRLADVAGWKAVLFQFVMFPWRIASFVVTLTLLLTGWVVALLPLYAWVFPTFVGWPGYQLFDWTDGAGVRHAYYLESFWQIGAASLVGIGLVLLTPVVVRALNGVDRAAVRGLLAG
>NZ_CP047147.1|WP_159312585.1|3416206_3416905_-|hypothetical-protein
MNPDMAPPPPLDDPVERYAVELAAALRGPAGARERLVVEVRDGLAETVAAYEAAGVPAERAVREAVAEFGSVAEVAASCQRELTVAQARHTARALALTGPFLVACWWLVRGTRDGQGGVSGFAQQVAVQLSSAAAVAVVLAALALAATGAWGRWLPVAAERLPAAVAWAGTAASVAMAVTTLTLATAAFLAEQWPLTVLAGALAAASHAVVAGSARVCRECARLSAREPALA
>NZ_CP047147.1|WP_003949238.1|3416901_3417255_-|PadR-family-transcriptional-regulator
MRHDAVRGHLDGLLLAVVEPGPLHGYAIITAVQERSGGALELRTGTIYPALNRLERVGLLRSDWEAVGQRKRRRYELTEAGRRQLAEERSAWRDFTRVIGAVLDPAPVPGAATGAAT
>NZ_CP047147.1|WP_030771201.1|3417385_3417847_+|DUF2269-family-protein
MAKLFLSLHVLAAILAIGPITVAASMFPRLARTAPTPETPALLHKICRSYAYVGAAVPVLGIATGAALGVLSDAWLVVSIVLTGVAAGVLVAVILPGQSELLEPLEGDEGAVAGEEERRAAGARLAMTTGVFNLLWAAVVVLMIVRPGSTTGA
>NZ_CP047147.1|WP_159312586.1|3417861_3419106_-|MFS-transporter
MPLALLALSVVAFGIGTTEFVSMGLLPQIADGVGVSVPQAGNLISAYALGVVVGAPLLTGLGAKIPHKKLLLLLAGLFVVGNVASALAPGFGTLFAARVLAGLPHGALFGVGAVVASRLVAPERAARAVSTMFLGLTVANIVGVPAGTALGQQFGWRSAYLAVAVIGLIALAALARLVPHQPRAEGAGIRHELKAMGNRHIAIGLATAVVGFGGCFAVYSYLVPMLTEVTGMASASTTLVLALYGVGMTLGTLLAGPMTDRALRPTLYGGLAVMAVVLFAFYFAVQHTVTALVCVLLIGAMGSFITTPVQMLLMAKAEQAPTMAAASNHSAFNLANAGGAWLGGLVISAGWGWASPALVGASLAAVGLGLAVVGGVMDGGFGRGKRSTVVAGAAAKAGVKDEAEVQAAGVERAG
>NZ_CP047147.1|WP_159312587.1|3419489_3420158_+|DUF998-domain-containing-protein
MTGTFTTPGPLHSAAATQRSTARWLTTGGVVAGPLFLAAGLAQGLTREGFDFTRNAISQLALGGAGWVQTLSFVCTGALLVAGAAGLRRTLRRGSAGRWAPALVGVFGLSFWAAAAFPADAGAGFPAGSPDATVMSGHGAAHMAAGMIGYLALCAAFVVLARPLAARGLRGWAVASRVAPVAVLAGFMASAASVLAFTAGAGLGLLWLSAVMARLADAPGDR

Crispr_ID: NZ_CP047147_16

• CRISPR_ID: NZ_CP047147_16
• CRISPR_location: 3542425-3542527
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP047147_16

Consensus_repeat	Method
TGGCGATGTTTCACGTGAAACATC	CRISPRCasFinder

spacers of NZ_CP047147_16

>16.1|3542449|55|NZ_CP047147|CRISPRCasFinder
GCCACGACGCGAGCGCGTGCGTCCCGGGCGCCCGGGTCCCGGACAACGAGGAGGG

CRISPR arrays and Neighbor proteins around NZ_CP047147_16

CRISPR arrays

The CRISPR arrays of NZ_CP047147_16

>merge|NZ_CP047147|16|3542425-3542527|CRISPRCasFinder
TGGCGATGTTTCACGTGAAACATCGCCACGACGCGAGCGCGTGCGTCCCGGGCGCCCGGGTCCCGGACAACGAGGAGGGCTGGGATGTTTCACGTGAAACATC

>NZ_CP047147|16|15|3542425-3542527|CRISPRCasFinder
TGGCGATGTTTCACGTGAAACATC	GCCACGACGCGAGCGCGTGCGTCCCGGGCGCCCGGGTCCCGGACAACGAGGAGGG
CTGGGATGTTTCACGTGAAACATC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_015507545.1|3550850_3551267_+|hypothetical-protein	unknown	unknown	gnl|CDD|237865
NZ_CP047147.1|WP_159312623.1|3535775_3537074_-|class-E-sortase	unknown	unknown	gnl|CDD|320679
NZ_CP047147.1|WP_018470242.1|3552097_3552697_-|DUF3566-domain-containing-protein	unknown	unknown	gnl|CDD|378809
NZ_CP047147.1|WP_003949358.1|3544984_3545533_+|DNA-binding-protein	unknown	unknown	gnl|CDD|225320
NZ_CP047147.1|WP_159312622.1|3535018_3535792_-|class-E-sortase	unknown	unknown	gnl|CDD|320679
NZ_CP047147.1|WP_159312624.1|3537070_3537709_-|aminodeoxychorismate/anthranilate-synthase-component-II	unknown	unknown	gnl|CDD|181107
NZ_CP047147.1|WP_159312628.1|3545586_3546948_+|protein-kinase	unknown	unknown	gnl|CDD|270916
NZ_CP047147.1|WP_003949362.1|3550395_3550623_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159312629.1|3546934_3548227_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159312626.1|3542570_3543674_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159312631.1|3551420_3551714_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_003949349.1|3540716_3541250_-|peptidylprolyl-isomerase	unknown	unknown	gnl|CDD|223725
NZ_CP047147.1|WP_159312625.1|3538126_3538840_-|DUF881-domain-containing-protein	unknown	unknown	gnl|CDD|377575
NZ_CP047147.1|WP_159312627.1|3543885_3544548_+|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|380054
NZ_CP047147.1|WP_085478365.1|3532925_3534914_+|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase	unknown	unknown	gnl|CDD|270916
NZ_CP047147.1|WP_026235273.1|3539673_3540573_-|rhomboid-family-intramembrane-serine-protease	unknown	unknown	gnl|CDD|366759
NZ_CP047147.1|WP_003949345.1|3537705_3537882_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159312630.1|3548223_3550158_-|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|238733
NZ_CP047147.1|WP_003949350.1|3541590_3542319_+|DUF5324-family-protein	unknown	unknown	gnl|CDD|375085
NZ_CP047147.1|WP_003949347.1|3539051_3539306_+|cell-division-protein-CrgA	unknown	unknown	gnl|CDD|179394

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_015507545.1|3550850_3551267_+|hypothetical-protein	gnl|CDD|237865	PRK14951, PRK14951, DNA polymerase III subunits gamma and tau; Provisional.	0.00491906
NZ_CP047147.1|WP_159312623.1|3535775_3537074_-|class-E-sortase	gnl|CDD|320679	cd05830, Sortase_E, Sortase domain found in the class E family of sortases. Class E sortases are membrane-bound cysteine transpeptidases distributed in Gram-positive bacteria (mainly present in Actinobacteria). Genes encoding class A and E sortases are never found in the same organism, and similar to class A sortases, the genes encoding class E sortases are not positioned adjacent to genes encoding potential protein substrates, suggesting a housekeeping sortase function of class E sortases in some high G + C Gram-positive bacteria. Similar to class A sortase, class E sortases are capable of anchoring a large number of functionally distinct surface proteins containing a cell wall sorting signal to an amino group located on the bacterial cell wall. They recognize an LAXTG sorting signal, instead of the canonical LPXTG motif processed by class A sortases. The prototypical class E sortase from Corynebacterium diphtheria (named Cd-SrtF) is a non-polymerization sortase that is not required for pilus polymerization, and proceeds to complete the assembly process by anchoring the polymer to the cell wall peptidoglycan. Moreover, in Streptomyces coelicolor, one or both of Staphylococcus aureus SrtA homologs may function as class E sortase responsible for the cell wall anchoring of the long chaplin proteins (ChpA-C) containing an LAXTG sorting signal, which presumably mediate aerial hyphae formation. The family also includes some class E sortase homologs from Gram-negative and Archaebacterial species, but the functions of these enzymes are unknown.	4.42829e-48
NZ_CP047147.1|WP_003949358.1|3544984_3545533_+|DNA-binding-protein	gnl|CDD|225320	COG2522, COG2522, Predicted transcriptional regulator [General function prediction only].	0.00308131
NZ_CP047147.1|WP_159312622.1|3535018_3535792_-|class-E-sortase	gnl|CDD|320679	cd05830, Sortase_E, Sortase domain found in the class E family of sortases. Class E sortases are membrane-bound cysteine transpeptidases distributed in Gram-positive bacteria (mainly present in Actinobacteria). Genes encoding class A and E sortases are never found in the same organism, and similar to class A sortases, the genes encoding class E sortases are not positioned adjacent to genes encoding potential protein substrates, suggesting a housekeeping sortase function of class E sortases in some high G + C Gram-positive bacteria. Similar to class A sortase, class E sortases are capable of anchoring a large number of functionally distinct surface proteins containing a cell wall sorting signal to an amino group located on the bacterial cell wall. They recognize an LAXTG sorting signal, instead of the canonical LPXTG motif processed by class A sortases. The prototypical class E sortase from Corynebacterium diphtheria (named Cd-SrtF) is a non-polymerization sortase that is not required for pilus polymerization, and proceeds to complete the assembly process by anchoring the polymer to the cell wall peptidoglycan. Moreover, in Streptomyces coelicolor, one or both of Staphylococcus aureus SrtA homologs may function as class E sortase responsible for the cell wall anchoring of the long chaplin proteins (ChpA-C) containing an LAXTG sorting signal, which presumably mediate aerial hyphae formation. The family also includes some class E sortase homologs from Gram-negative and Archaebacterial species, but the functions of these enzymes are unknown.	5.93487e-40
NZ_CP047147.1|WP_159312624.1|3537070_3537709_-|aminodeoxychorismate/anthranilate-synthase-component-II	gnl|CDD|181107	PRK07765, PRK07765, aminodeoxychorismate/anthranilate synthase component II.	6.19051e-141
NZ_CP047147.1|WP_159312628.1|3545586_3546948_+|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	5.42974e-71
NZ_CP047147.1|WP_003949349.1|3540716_3541250_-|peptidylprolyl-isomerase	gnl|CDD|223725	COG0652, PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family [Posttranslational modification, protein turnover, chaperones].	3.7751e-62
NZ_CP047147.1|WP_018470242.1|3552097_3552697_-|DUF3566-domain-containing-protein	gnl|CDD|378809	pfam12089, DUF3566, Transmembrane domain of unknown function (DUF3566). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 136 to 304 amino acids in length. This region represents a transmembrane region found at the C-terminus of the proteins.	4.28856e-55
NZ_CP047147.1|WP_159312625.1|3538126_3538840_-|DUF881-domain-containing-protein	gnl|CDD|377575	pfam05949, DUF881, Bacterial protein of unknown function (DUF881). This family consists of a series of hypothetical bacterial proteins. One of the family members YlxW from Bacillus subtilis is thought to be involved in cell division and sporulation.	7.31687e-51
NZ_CP047147.1|WP_159312627.1|3543885_3544548_+|TetR-family-transcriptional-regulator	gnl|CDD|380054	pfam17920, TetR_C_16, Tetracyclin repressor-like, C-terminal domain. TetR family regulators are involved in the transcriptional control of multidrug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. The TetR proteins identified in overm ultiple genera of bacteria and archaea share a common helix-turn-helix (HTH) structure in their DNA-binding domain. However, TetR proteins can work in different ways: they can bind a target operator directly to exert their effect (e.g. TetR binds Tet(A) gene to repress it in the absence of tetracycline), or they can be involved in complex regulatory cascades in which the TetR protein can either be modulated by another regulator or TetR can trigger the cellular response. This entry represents the C-terminal domain found in a number of different TetR transcription regulator proteins found in Actinobacteria. TetR regulates the expression of the membrane-associated tetracycline resistance protein, TetA, which exports the tetracycline antibiotic out of the cell before it can attach to the ribosomes and inhibit protein synthesis. TetR blocks transcription from the genes encoding both TetA and TetR in the absence of antibiotic. The C-terminal domain is multi-helical and is interlocked in the homodimer with the helix-turn-helix (HTH) DNA-binding domain.	9.30949e-20
NZ_CP047147.1|WP_085478365.1|3532925_3534914_+|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	8.25821e-127
NZ_CP047147.1|WP_026235273.1|3539673_3540573_-|rhomboid-family-intramembrane-serine-protease	gnl|CDD|366759	pfam01694, Rhomboid, Rhomboid family. This family contains integral membrane proteins that are related to Drosophila rhomboid protein. Members of this family are found in bacteria and eukaryotes. Rhomboid promotes the cleavage of the membrane-anchored TGF-alpha-like growth factor Spitz, allowing it to activate the Drosophila EGF receptor. Analysis has shown that Rhomboid-1 is an intramembrane serine protease (EC:3.4.21.105). Parasite-encoded rhomboid enzymes are also important for invasion of host cells by Toxoplasma and the malaria parasite.	2.42577e-36
NZ_CP047147.1|WP_159312630.1|3548223_3550158_-|VWA-domain-containing-protein	gnl|CDD|238733	cd01456, vWA_ywmD_type, VWA ywmD type:Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains. Not much is known about the function of the members of this subgroup. All members of this subgroup however have a conserved MIDAS motif. .	2.79008e-20
NZ_CP047147.1|WP_003949350.1|3541590_3542319_+|DUF5324-family-protein	gnl|CDD|375085	pfam17258, DUF5324, Family of unknown function (DUF5324). This is a family of unknown function, mostly found in Actinobacteria. Most of the family members contain one trans-membrane domain.	7.83698e-96
NZ_CP047147.1|WP_003949347.1|3539051_3539306_+|cell-division-protein-CrgA	gnl|CDD|179394	PRK02251, PRK02251, cell division protein CrgA.	8.01203e-38

Protein sequences

>NZ_CP047147.1|WP_003949350.1|3541590_3542319_+|DUF5324-family-protein
MTRIDSVRAATGSAKESARHAAEAVAPYAETAKERAAHLSHEARVRLAPKVSLAAAQAADQARLRYDAHLAPHVEHALAHVPPKVDEVAHKAAVHTKRAAHQAAAYSRPRLEQAVAAAQPAREEAAARSAAALAALRGQVSAQQIEKLARKQQRKGRGKRFAVSILVLGAVSGAALAAWKWWDKQANPDWLVEPPAPTEVPDGPPLTSVDGTGQGLLDPEVRAKQADAEADSLDEEGGSRSA
>NZ_CP047147.1|WP_003949349.1|3540716_3541250_-|peptidylprolyl-isomerase
MAEQLYATLKTNHGDINVRLFPNHAPKTVKNFVGLATGEQEWTNPETGQKTSDKLYDGTVFHRVISGFMLQGGDPLGNGTGGPGYQFADEFHPDLAFNKPYLLAMANAGPGTNGSQFFITVAPTAWLTNKHTIFGEVVDPASQKVVDEIAAVQTNPRTDRPVNDVVIESVVVENREG
>NZ_CP047147.1|WP_026235273.1|3539673_3540573_-|rhomboid-family-intramembrane-serine-protease
MDQGPSGAPGARDAHSLPGCYRHPDRETGISCVRCERPICPECMVSASVGFQCPDCVRGGSGTGSSAVNAPRTIAGGTITADPRLLTKILLGINAAVFLAVLVLGDEFVAHLMLVGAFPPPEFGWEPVMGVAAGEWYRLITSVFAHQEFLHFASNMLLLWWLGGPLEAALGRVRYLALYLISGLAGGALTYVIAAPQQPSLGASGAVFGLMGATVVLMRRLNQDLRPVLVLVALNLVFTVLAPRIAWEAHVGGLVAGAIIGYAMVHAPRGRRALIQWGTCGAVLVVVLVMIVVRTMALT
>NZ_CP047147.1|WP_003949347.1|3539051_3539306_+|cell-division-protein-CrgA
MPKSRIRKKADYTPPPAKQSTEIKLTSRSWVAPVMLALFLIGLAWIVVFYLTDGSLPIDAFGNWNIVIGFGFIAAGFGVSTQWK
>NZ_CP047147.1|WP_159312625.1|3538126_3538840_-|DUF881-domain-containing-protein
MRLLTVGVFALAGLIFVTSFNTARGTNIRTDTALLKLSDLIRDRSHKNGELDEANSALRKKVEALAERDDGSTEAEDAKLGALEKSAGTKPISGPSVSVTLDDAPPDATAKLPGYPEPHPNDLVIHQQDLQAVVNALWKGGAKGIEVMGQRLISTSAVRCVGNTLILQGRVYSPPYNVTAVGDQEKLKQALAESPEIQNYMLYVNAYGLGWKVEDAGKTRLDGYSGTVDLHYAKPAS
>NZ_CP047147.1|WP_003949345.1|3537705_3537882_-|hypothetical-protein
MYGWIWRHLPGNAWVRAFISLILALAVVYALFEYVFPWAEPLLPFNDVTVDDAQGAHR
>NZ_CP047147.1|WP_159312624.1|3537070_3537709_-|aminodeoxychorismate/anthranilate-synthase-component-II
MSARILVVDNYDSFVFNLVQYLYQLGAECEVVRNDEVRTSHAQDGFDGVLLSPGPGAPEQAGVCIEMVRHCAETGVPVFGVCLGMQSMAVAYGGVVDRAPELLHGKTSPVFHEGRGVFAGLPSPFIATRYHSLAAEPQRVPEELEVTARTADGIIMGVRHRTLPVEGVQFHPESVLTEHGHLMLANWLAECGDAGAVGRSSGLAPVVGKATE
>NZ_CP047147.1|WP_159312623.1|3535775_3537074_-|class-E-sortase
MTALRPERESAAGGPVDPLTDPLPDVLAGGHSSPWFRAEQPPQQVQGHDHPAPQPPLADPYAQLPADAYAAPPQDDAYAGHSPYEGGPGWTTSPETYPAPEVAEEPYSPVPEAPRDDETMALRAADPARTDEERDETQPATIAAGAEGGRAARRKAAKRNARPGGRRGTGRRRAGAPAPEASGAPGGGDEPPERPRTRVEARRAARARKPSAATVASRAVGELFITIGVLMLLFVTYQLWWTNVRAQQQADGAAHNLQQDWEQGKRKPGAFQAGQGFAILHIPKLDVVVPVASGIDKQRVLDRGMAGHYAEGALKTALPSAKEGNFAVAGHRNTHGEPFRYINRLTPGDPIVVETQDTYYVYEMASILPQTPPSNTAVIDPVPAGSGFTEPGRYLTLTTCTPEFTSTYRMIVWGKMVEERPRSKGKPDALVD
>NZ_CP047147.1|WP_159312622.1|3535018_3535792_-|class-E-sortase
MRSSIESDRTDGAGSVAATKTQDRTGEESVTAPRRRKRGIIATTVGVFGELLITAGVVLGLFVAYSLWWTNVVADREAGKQGDAVRDRWAGGPGALDTKDGVGFLHVPAMKNGEVLVKKGTEGSILNKGVAGYYTDPVKSALPSDDKGNFTLAAHRDGHGAKFHNIDKIKKGDPIVFETKESWYVYKTFAILPETSKYNVEVLDAVPKESGAEKPGRYITLTTCTPVYTSDYRYIVWGELDRVEKVDNQRTPPAELG
>NZ_CP047147.1|WP_085478365.1|3532925_3534914_+|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase
MEEPRRLGGRYELGSVLGRGGMAEVYLAHDTRLGRTVAVKTLRADLARDPSFQARFRREAQSAASLNHPAIVAVYDTGEDYVDGVSIPYIVMEYVDGSTLRELLHSGRKLLPERSMEMTIGILQALEYSHRAGIVHRDIKPANVMLTRNGQVKVMDFGIARAMGDSGMTMTQTSAVIGTAQYLSPEQAKGEQVDARSDLYSTGCLLYELLTVRPPFVGDSPVAVAYQHVREEAQAPSVFDPEITPEMDAIVLKALVKDPDYRYQSADEMRADIEACLDGQPVGATAAMGAVGYGGYPDDQPTTAMRPQDGAAATSMLPPVNPDDGGYGYDDRPGRRRQQPKKNTNTSTILLIAAGVLVLIGAIFIGKSLFGGGGGDNKVSVPNLVGSTLSEAKKKAGNVDLELNVSAREECEDQPAKHICSQDPEPGGGDGAKVERGSTVSVVVSTGAPKITVPDVQGLSFEKAEEQLKAKGFTDIEQKAEESDQTPGTVIGQDPDRDSEVEKGTTITLTVAKEKAMTAVPDVSGKSCEEATSQLEGSDLKANCVEEENEAEAGKVFSQTPAAQAQVQPGSTVTLKIAKAAEKVKVPGGLRGQKLGDVKKALTDAGLTVGNVSGSPDDNALVAALDPGEDAEVPKGTAVNLTTVGPPGEDGGGIFGGNRGRD
>NZ_CP047147.1|WP_159312626.1|3542570_3543674_-|hypothetical-protein
MASTPHENEPGSRHPDGGASVAPADEGDREVRGEGGGSGKGAAKKLLPVVLVLTGVLSAMLVVFGLPAVNGGPHHVPVGLVGPQAAAEALGKQLDQRQPDGWEVTSYPSTDALTQAIHDRDVMGGFAPDGQTLTVYTASAAGNPSSAAINGIGNALAAQQGMEATTENVVPFPEDDPNGAGLTAAALPMIIGGVLPAVAMVRLFPGHGGLRLRLTGAVLFALAAGFALAAIIQFGFGSVDGTYWTTALGLSLGMAALTLPFLGLESLFGFVGLGAGIVVMMFVGNSLSGLATGAHWLPNGWATLGQLMPPGASGSLLRANGFFDGTGAGGPVAVLAAWAVIGLLLILLADRRGGRGTEEKQAEAATA
>NZ_CP047147.1|WP_159312627.1|3543885_3544548_+|TetR-family-transcriptional-regulator
MTLPRSTPPEPHPQPPETPRPPQRHQGGRRPGENRTREQILDAARECFAERGYDATSVRRIAETAGVDQALVHHFYGTKEKLFLNALEIPLRMPEALAEAAAGDRVGLGSRIVLAHLRVWEDASARPAMMTTLRSAATHRSAAAVLRDYAKGSIREALGKVITGEDVELRIALIATTLIGLSLTRHLVRLDPVPEASPQELAARLGPVIDLHLDPVTPAA
>NZ_CP047147.1|WP_003949358.1|3544984_3545533_+|DNA-binding-protein
MDAAQQEATARARELQRNWYGEPLGALFRRLIDDLGLNQARLASVLGLSAPMLSQLMSGQRAKIGNPAVVQRVQLLQDLAGQVADGSVSAGEASARMDEIKKSQGGSVLSQTGQTATGSGAPTVKRVVREIQSLLRSVAAAGDIIDAADTLAPTHPELAEFLRVYGAGRTAEAVAHYESHQN
>NZ_CP047147.1|WP_159312628.1|3545586_3546948_+|protein-kinase
MGEVFAGRYELADPIGRGGVGAVWRAWDHRRRRYVAAKVLQQSDAHTLLRFVREQALRIDHPHVLAPASWAADDDQVLFTMDLVGGGSLAHLIGDYGALPPHFVALLLDQLLAGLAAVHAEGVIHRDIKPANILLEATGSGRPHLRLSDFGISMRQGEPRLTETNYVVGTPGYFAPEQLLGAEPDFTADLFAVGLVALYLLQGRKPDSQALVEHFAAHGTPSAPEGIPEPLWQVVATLLQPDPQARFRTATGARKALASASELLPGPGAEEEPVEVFDQIGPLPPGFGPDGPEAKASEAADQAQAQTQATGATNPAAAPERPSTDGFPLAPPAPPAQDPTFVPAQAPTASVHQPAPTAPPAAPAPVYADTRPYTAPGQPHPGQQPPFPAQPGYGYPQAPPQGYGYPPPGSPAPYPQAPAATPTRPGPSPKIAVPVLLVALVCLAVGFWALTQT
>NZ_CP047147.1|WP_159312629.1|3546934_3548227_-|hypothetical-protein
MRGRGLGAAGLALAAAVLGTAPAQAEGGTSPYVFADGAARVAGEVSSTDAHTLAAGRPYRSQIGPGEELYYAVDLDATSYAYASAVAVPKPGAKVGTRDRLTVTLRDRRDNQCGTGDTRFGSAAYPRPLAAQAVRAVKPDGGTCQEAGPYFLVVERETGGTSAQEPWELELRLLTEPAVQGKGGPTEAPSPSPTDAPADVPGGEPVARPGGTGFNDAVALGDGSFKTRLKPGGTTFYRVPVDWGQRLYVEPELGSATTDKSMAYVSSALETALYNPAFGPVDDGSLLFNGSPQTLASEPLQPIAYENRHASAPSVKGTRFAGWYYVQLTLSPKMAEVFRGDDFGVTLRVRVQGEPVAGPRYAGDAGPFQVGDREREAAEAGRSDAEVARSETMAVVAASGIGTGTVLLVGLGVWFWVARRGAAGSRVRSG
>NZ_CP047147.1|WP_159312630.1|3548223_3550158_-|VWA-domain-containing-protein
MKARLGRRTAAVILAGVVGALATGPPATAEPAPGAGGLVMVLDSSGSMADEAGGGRTRIEAARDAVGTVVDSLPDGYPTGLRVYGADRTSGCTDTRLARPVEPLDRDAMKKAVAGVEPKGDTPIGLSLRKAVADLPEPEPGAVGRRTVLLISDGEDNCGSPPPCEAAEELAESGLDLRIDAIGFQVEGKAREELTCVAEAGHGAYYDAPDAEALARQLQRAAELSAGGYQFKGEPIEGAASAKGAPTVGPGQYLDSIGPGETRWYAAGLDATGTADFGVTAVPQPGVPVGYSDGLELRVHTSGEFPTVCDSTRATFRQDEGALPVSGAVSRVPTAKANAACDRASTYHLEVERVSAKGSDQARWPLELRMAVEEPLAAGTVPAQSATEFGEISRDQVPRVDGPAKAVTGGTGFNDAVRIGEGVWKDGLLPAQTRWYKVKAGWGQQLRYTVDFGNEPTVDHDDLVIRRSFVSTSLYAPSRAPVGTGTEFSDYQGYFGKPSVLDHGTVPVTWTNRWEPAAHVKPVRAAGDYYLAISLGPNTATFAENPAVGVVLRVEVAGTELAGPQKDAPAAAGTPDEAPAAGAGAEEAPPVKDTAAAEEAGWPSPWVLAAAGGALALLVVAAAALVARRRAGRGAGGPTRGGTA
>NZ_CP047147.1|WP_003949362.1|3550395_3550623_-|hypothetical-protein
MRGERGTGHRSISVGVYSRPSEVSYVNERRGRAVKKLLLVALAAIGGLLVYRQIQADRAEQDLWTEATDSVPTGS
>NZ_CP047147.1|WP_015507545.1|3550850_3551267_+|hypothetical-protein
MASKAAHLWTVLVGAFLSLFAALGFSAPASATAPQAQPQPEPRPQSAPQQTPAAPCSAPVDLTGAAPQWSLGLDRSMPPTMKQRITAEAHGSSPTCRSTVADAVVTPADADREPSDMTDRAAESLATPVRGSDHENPP
>NZ_CP047147.1|WP_159312631.1|3551420_3551714_-|hypothetical-protein
MTDEPGRPLGELRKGEVVRATVTSHQPWGFTARLDAYEPVGASLDMIRRGAEPGVERLARRLPPVGATVDLVVGEVRDWHHEPWMWIDLTAPGAAEE
>NZ_CP047147.1|WP_018470242.1|3552097_3552697_-|DUF3566-domain-containing-protein
MTDTREPDSLGAQPYPGTQGGGRQYQGYDQYEAGPLPGERPGADAGPAQPYTPPQAYATPEQAGVRRPRTGARTQPRTRKARLRVAKADPWSVMKVSFLLSIALGICTIVAAAVLWMVMDAMGVFSTVGGTIAEATGSSESNGFDLQSFLSLPRVLMFTSIIAVIDVVLATALATLGAFIYNLSAGFVGGVELTLAEDE

Crispr_ID: NZ_CP047147_17

• CRISPR_ID: NZ_CP047147_17
• CRISPR_location: 3596798-3596936
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP047147_17

Consensus_repeat	Method
CCGGCGGTGGCCAGCAGCAGGGTGGCGGCGG	CRISPRCasFinder

spacers of NZ_CP047147_17

>17.1|3596829|77|NZ_CP047147|CRISPRCasFinder
CGGCGGCCCCGGCGGTGGCCAGCAGCAGGGTGGCGGCGGTGCTCCCGCCGACGACCCCTGGGCCACCAGCGCGCCTT

CRISPR arrays and Neighbor proteins around NZ_CP047147_17

CRISPR arrays

The CRISPR arrays of NZ_CP047147_17

>merge|NZ_CP047147|17|3596798-3596936|CRISPRCasFinder
GGGGTGGCGGCGGCCAGCAGGGCGGCTGGGGCGGCGGCCCCGGCGGTGGCCAGCAGCAGGGTGGCGGCGGTGCTCCCGCCGACGACCCCTGGGCCACCAGCGCGCCTTCCGGCGGCGGCCAGCAGCAGGGTGGCGGCGG

>NZ_CP047147|17|16|3596798-3596936|CRISPRCasFinder
GGGGTGGCGGCGGCCAGCAGGGCGGCTGGGG	CGGCGGCCCCGGCGGTGGCCAGCAGCAGGGTGGCGGCGGTGCTCCCGCCGACGACCCCTGGGCCACCAGCGCGCCTT
CCGGCGGCGGCCAGCAGCAGGGTGGCGGCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_003949404.1|3597315_3597762_+|50S-ribosomal-protein-L9	unknown	unknown	gnl|CDD|234659
NZ_CP047147.1|WP_159312638.1|3604042_3605446_+|serine-hydrolase	unknown	unknown	gnl|CDD|365903
NZ_CP047147.1|WP_008408220.1|3606156_3606615_-|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NZ_CP047147.1|WP_003949395.1|3588949_3591265_+|penicillin-binding-protein	unknown	unknown	gnl|CDD|223815
NZ_CP047147.1|WP_093846943.1|3591379_3592918_+|DUF2029-domain-containing-protein	unknown	unknown	gnl|CDD|227937
NZ_CP047147.1|WP_010644352.1|3597899_3599237_-|MATE-family-efflux-transporter	unknown	unknown	gnl|CDD|240541
NZ_CP047147.1|WP_003949400.1|3596031_3596322_+|30S-ribosomal-protein-S6	unknown	unknown	gnl|CDD|179034
NZ_CP047147.1|WP_003949406.1|3599706_3601176_+|replicative-DNA-helicase	unknown	unknown	gnl|CDD|273206
NZ_CP047147.1|WP_159312635.1|3584985_3586245_-|MFS-transporter	unknown	unknown	gnl|CDD|340863
NZ_CP047147.1|WP_003949403.1|3597060_3597297_+|30S-ribosomal-protein-S18	unknown	unknown	gnl|CDD|178997
NZ_CP047147.1|WP_003949393.1|3586386_3587469_-|inositol-3-phosphate-synthase	unknown	unknown	gnl|CDD|132491
NZ_CP047147.1|WP_003949398.1|3594116_3595238_-|peptidoglycan-bridge-formation-glycyltransferase-FemA/FemB-family-protein	unknown	unknown	gnl|CDD|225224
NZ_CP047147.1|WP_018470259.1|3601200_3601770_-|deaminase	unknown	unknown	gnl|CDD|334719
NZ_CP047147.1|WP_003949399.1|3595413_3595728_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159312636.1|3601926_3602469_+|sugar-O-acetyltransferase	unknown	unknown	gnl|CDD|100047
NZ_CP047147.1|WP_003949397.1|3592996_3594028_-|alanine-racemase	unknown	unknown	gnl|CDD|143481
NZ_CP047147.1|WP_159312639.1|3605602_3606106_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NZ_CP047147.1|WP_159312637.1|3602581_3603730_+|serine-hydrolase	unknown	unknown	gnl|CDD|365903
NZ_CP047147.1|WP_003949394.1|3587527_3588205_-|PadR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224609
NZ_CP047147.1|WP_003949391.1|3584340_3584868_-|hypothetical-protein	unknown	unknown	gnl|CDD|370676

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_003949404.1|3597315_3597762_+|50S-ribosomal-protein-L9	gnl|CDD|234659	PRK00137, rplI, 50S ribosomal protein L9; Reviewed.	2.29206e-65
NZ_CP047147.1|WP_159312638.1|3604042_3605446_+|serine-hydrolase	gnl|CDD|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	1.42999e-52
NZ_CP047147.1|WP_003949395.1|3588949_3591265_+|penicillin-binding-protein	gnl|CDD|223815	COG0744, MrcB, Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane].	1.63674e-145
NZ_CP047147.1|WP_093846943.1|3591379_3592918_+|DUF2029-domain-containing-protein	gnl|CDD|227937	COG5650, COG5650, Predicted integral membrane protein [Function unknown].	8.73543e-40
NZ_CP047147.1|WP_010644352.1|3597899_3599237_-|MATE-family-efflux-transporter	gnl|CDD|240541	cd13136, MATE_DinF_like, DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Escherichia coli DinF is a membrane protein that has been found to protect cells against oxidative stress and bile salts. The expression of DinF is regulated as part of the SOS system. It may act by detoxifying oxidizing molecules that have the potential to damage DNA. Some member of this family have been reported to enhance the virulence of plant pathogenic bacteria by enhancing their ability to grow in the presence of toxic compounds. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	1.91963e-114
NZ_CP047147.1|WP_003949400.1|3596031_3596322_+|30S-ribosomal-protein-S6	gnl|CDD|179034	PRK00453, rpsF, 30S ribosomal protein S6; Reviewed.	6.81915e-39
NZ_CP047147.1|WP_003949406.1|3599706_3601176_+|replicative-DNA-helicase	gnl|CDD|273206	TIGR00665, DnaB, replicative DNA helicase. This model describes the helicase DnaB, a homohexameric protein required for DNA replication. The homohexamer can form a ring around a single strand of DNA near a replication fork. An intein of > 400 residues is found at a conserved location in DnaB of Synechocystis PCC6803, Rhodothermus marinus (both experimentally confirmed), and Mycobacterium tuberculosis. The intein removes itself by a self-splicing reaction. The seed alignment contains inteins so that the model built from the seed alignment will model a low cost at common intein insertion sites. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP047147.1|WP_159312635.1|3584985_3586245_-|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	9.03666e-36
NZ_CP047147.1|WP_003949403.1|3597060_3597297_+|30S-ribosomal-protein-S18	gnl|CDD|178997	PRK00391, rpsR, 30S ribosomal protein S18; Reviewed.	9.24137e-38
NZ_CP047147.1|WP_003949393.1|3586386_3587469_-|inositol-3-phosphate-synthase	gnl|CDD|132491	TIGR03450, mycothiol_INO1, inositol 1-phosphate synthase, Actinobacterial type. This enzyme, inositol 1-phosphate synthase as found in Actinobacteria, produces an essential precursor for several different products, including mycothiol, which is a glutathione analog, and phosphatidylinositol, which is a phospholipid.	0
NZ_CP047147.1|WP_003949398.1|3594116_3595238_-|peptidoglycan-bridge-formation-glycyltransferase-FemA/FemB-family-protein	gnl|CDD|225224	COG2348, COG2348, Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis].	1.68286e-39
NZ_CP047147.1|WP_018470259.1|3601200_3601770_-|deaminase	gnl|CDD|334719	pfam01872, RibD_C, RibD C-terminal domain. The function of this domain is not known, but it is thought to be involved in riboflavin biosynthesis. This domain is found in the C-terminus of RibD/RibG, in combination with pfam00383, as well as in isolation in some archaebacterial proteins. This family appears to be related to pfam00186.	1.02223e-20
NZ_CP047147.1|WP_008408220.1|3606156_3606615_-|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.44958e-13
NZ_CP047147.1|WP_159312636.1|3601926_3602469_+|sugar-O-acetyltransferase	gnl|CDD|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	1.9409e-63
NZ_CP047147.1|WP_003949397.1|3592996_3594028_-|alanine-racemase	gnl|CDD|143481	cd00430, PLPDE_III_AR, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase. This family includes predominantly bacterial alanine racemases (AR), some serine racemases (SerRac), and putative bifunctional enzymes containing N-terminal UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase (murF) and C-terminal AR domains. These proteins are fold type III PLP-dependent enzymes that play essential roles in peptidoglycan biosynthesis. AR catalyzes the interconversion between L- and D-alanine, which is an essential component of the peptidoglycan layer of bacterial cell walls. SerRac converts L-serine into its D-enantiomer (D-serine) for peptidoglycan synthesis. murF catalyzes the addition of D-Ala-D-Ala to UDPMurNAc-tripeptide, the final step in the synthesis of the cytoplasmic precursor of bacterial cell wall peptidoglycan. Members of this family contain an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain. They exist as homodimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. AR and other members of this family require dimer formation and the presence of the PLP cofactor for catalytic activity. Fungal ARs and eukaryotic serine racemases, which are fold types I and II PLP-dependent enzymes respectively, are excluded from this family.	5.44354e-10
NZ_CP047147.1|WP_159312639.1|3605602_3606106_-|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	9.96598e-20
NZ_CP047147.1|WP_159312637.1|3602581_3603730_+|serine-hydrolase	gnl|CDD|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	1.46481e-48
NZ_CP047147.1|WP_003949394.1|3587527_3588205_-|PadR-family-transcriptional-regulator	gnl|CDD|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	4.92242e-19
NZ_CP047147.1|WP_003949391.1|3584340_3584868_-|hypothetical-protein	gnl|CDD|370676	pfam09770, PAT1, Topoisomerase II-associated protein PAT1. Members of this family are necessary for accurate chromosome transmission during cell division.	8.0051e-05

Protein sequences

>NZ_CP047147.1|WP_003949400.1|3596031_3596322_+|30S-ribosomal-protein-S6
MRHYEVMVILDPDLEERSVAPLIENFLSVVREADGKVEKVDTWGRRRLSYEIKKKPEGIYSVIDLQAEPAVVKELDRQMNLNESVLRTKVLRPETH
>NZ_CP047147.1|WP_003949399.1|3595413_3595728_-|hypothetical-protein
MAQTTRPKTAGSLFATDGKPHPLQDSLMVVTLVLGALALVTAGFHHLHLISSWAGLVGILTGAYGQFISETTRERTLLIVGLGASAIGFYLGVAHGGLFGGVIT
>NZ_CP047147.1|WP_003949398.1|3594116_3595238_-|peptidoglycan-bridge-formation-glycyltransferase-FemA/FemB-family-protein
MSLTLRTISREQHLAYIQTLPAASHMQVPAWADVKAEWRSESLGWFDDRTGEMVGAGLVLYRQLPKIKRYLAYLPEGPVINWFSPHLEEWLQPMLAHLKQQGAFSVKMGPPVIIRRWEAASIKKGIQDPDVKRLRDVEADFIEPRAFEVADRLRRMGWQQGEDGGAGFGDVQPRYVFQVPLANRSLEDVHKGFNQLWRRNIKKAEKAGVEVVQGGYQDLEEWQRLYEVTAERDRFRPRPLGYFQRMWTALNNEDPNRMRLYFARHEGENVAAATMLVVGGHVWYSYGASANHKREVRPSNAMQWRMLRDAYALGATVYDLRGISDSLDESDHLFGLIQFKVGTGGQAAEYLGEWDFPLNKLLHKALDIYMSRR
>NZ_CP047147.1|WP_003949397.1|3592996_3594028_-|alanine-racemase
MALTLYVDTARWRDHHHQVREQFPGIVPVCKGNGYGFGHERLAEEAIRFGSDILAVGTTYEAARIKDWFSGDLLVLTPFRRGEEPVPLPDRVIRSVSSVDGVHGLVGARVVIEVMSSMKRHGVSEEDLPKLHAAIEDVRLEGFAIHLPLDRTDGTDAVEEVIAWMDRLRAHRLPLHTMFVSHLKSSELARLQQQFPQTRFRARIGTRLWLGDEEATEYRGAVLDVTQVSKGDRFGYRQQKAAGDGYLVVVAGGTSHGVGLESPKALHGVMPRAKGVARAGLATVNRNLSPFVWAGKQRWFAEPPHMQVSILFVPADAPAPQVGDELVAHLRHTTTQYDRVVER
>NZ_CP047147.1|WP_093846943.1|3591379_3592918_+|DUF2029-domain-containing-protein
MAPMPSPETTRADAPQRDTVQPTRQDEVAAAGSELIGGPAGRRVLAGGSWWSPVRVIALVMIGMFALGMVQKLPCYNGAWFFGAGAQYTHACYSDIPHLFQGRGFADGLVPYFDRLPGDMQFLEYPVLTGVFMEVASWFTPGSGSLVEREQIYWLINAGMLMACAAVIAVCVARTHRRRPWDALLVALAPAMALTATINWDLLAVALTAAALFLWSRERPLAFGVLLGLATAAKLYPALILGPLFLLCWRAGKWRAFGTALAGAAGAWLVVNGPVMIGAFEGWSKFYTFSEERGVDFGSFWLVLSQNSDQPLATETVNTLATLLMVLACALIAVLVLMAPRRPRLAQVAFLVVAAFILTNKVYSPQYVLWLIPLAALARPRWRDFLIWQSCEVLYYFGIWMYLAYTSSGDAQRGLPLEGYHLAICLHLAGTLYLCAVVVRDALLPERDVVRRDGDDDPSGGVLDGAPDRFVLGYAAHPPQHAAHFSRPVVRWGAGQSVGEGLGAGGPATPGS
>NZ_CP047147.1|WP_003949395.1|3588949_3591265_+|penicillin-binding-protein
MPSWKQVTGTCLGFFGLLLATAGIGLAMVDIPDPQKTANVQKNVYYWSDNTQMVIAGGGDKNRQIVDIEEIPESMQNAVVAAENATFWDDNGVDPMGIARAAFNMAMGGSTQSGSTITQQYVKNTYLSQEQTLKRKFTELLISVKVGGVESKQTILAGYLNTAYYGRGAYGIEAAARAYYDKPALELDTSESAFLAATLNGPNLYDPAGGQGPGASAKENTERATNRWKFALRRMVEIGKLDQSTRQDILDKGFPTPNPPKPATNKAGQIGYLTDLADNYIVANTTLSRTELDRGGYKIHTTFDKKKMAALTKAVDKVEKANIDPKKRPKTDRYVQFGGASVEPKTGKIKAIYGGSDATVHFTNNADYTGVQVGSTFKPFVLSAAMEYGIRNPDLPPEQTEQQRTIVSPKSIYDGDNKLKVKNYDGTIWHNEKGEEWHQRNDGDRSEGDVDLRTAMQFSTNTPYIQLAMDVGLDKVRQTAEAAGIKKDNLPGWRSPSFALGTSAPSAIRLAGAYATFAASGKQVDPYSVESIEGKDGEVWNHDSVAKVKQGIPADVADNVTDVLRTVVQEGTGTAAKPVDAQWPTAGKTGTTDGNKSAWFAGYTRQLSTAIGMFRVNDQAKNQKFLEMYGTGDQESIHGASFPAEIWTEYMLSAMKGKSPQQFPEPSELGTIVGEPTPTPTPTPTETEQEESPDPTPTTEAPPETPDPDPTTTCRPLDWECRQNENGGNENGGNENGGPGDPGGGQPTTEPPPEEGETEGNDNGGSWFGNN
>NZ_CP047147.1|WP_003949394.1|3587527_3588205_-|PadR-family-transcriptional-regulator
MSRRSGILEFAVLGLLRESPMHGYELRKRLNTSLGIFRAFSYGTLYPCLKTLVANGWLIEESSGPPEDAHAAPLTGRRAKIVYRLTAEGKEHFEDLLSQTGPDAYEDEHFAARFAFFGQTSRDVRMRVLEGRRSRLEERLEKMRASLARTRERLDDYTLELQRHGMESVEREVRWLNELIESERSGRHRRTGQDGSPQQGTSGEKDDLPRSREHSRPDSSDDTAT
>NZ_CP047147.1|WP_003949393.1|3586386_3587469_-|inositol-3-phosphate-synthase
MGSVRVAIVGVGNCAASLVQGVEYYKDADPDSKVPGLMHVQFGDYHVRDVEFVAAFDVDAKKVGLDLADAIGASENNTIKICDVPNSGVTVQRGHTLDGLGRYYRETIEESAEEPADIVQTLKDRQVDVLVCYLPVGSEDAAKYYAQCAIDAKVAFVNALPVFIAGTKEWADKFTEAGVPIVGDDIKSQVGATITHRVMAKLFEDRGVVLDRTMQLNVGGNMDFKNMLERDRLESKKISKTQAVTSQIRDRELGADNVHIGPSDYVAWLDDRKWAYVRLEGRAFGDVPLNLEYKLEVWDSPNSAGVIIDAVRAAKIAKDRGIGGPVLSASSYFMKSPPVQYFDDEAQANVEKFIKGEIER
>NZ_CP047147.1|WP_159312635.1|3584985_3586245_-|MFS-transporter
MAVVGDLRMLLRVRDFRRLLTVRLLSQAADGVFQVALATYVVFSPEKQTSAAAIASAMAVLLLPYSLIGPFAGVLLDRWRRRQVFLYGNLLRAVLAALTAALMVTGVPDWLFYVAALCVTAVNRFVLAGLSAALPRVVARDELVIANALSPTAGTLAATAGGGLAFLVRLLVADSDAVVLLLGGLLYLASAGASLTLAVSLLGPDPGQLQHLRGAVAGAARGLVAGVRHLREPGRRGAARALAAMAALRFCYGALTVMLLMLCRYAWSSDEDGGLALLGVAVAVSGAGFFVAALVTPSAARRLGAAGWIVACAAGAGVLELALGLTFAPVPLLAGAFVLGVATQGAKIATDTIVQASVSDDFRGRIFSVYDVLFNVAFVAAAGVSSLLLPADGKSAGLVVLVALIYGAVAVLMNRFDRQ
>NZ_CP047147.1|WP_003949391.1|3584340_3584868_-|hypothetical-protein
MTTPPPQGQNPYGQQPPQGQNPYGQQQAPGQPQQGVPPQGQPQGFPQQGPYAAPGMPGAAPEPPAKNKKKNILRVVGVVIALAVIGGGWWASQSDPAAAKAGDCVERGNDDDNNPELKIVECNSDTAEYKVLAKIEGKFIGMTAQSKCEDQAEGFKYAYTQTQGNDSFLLCLDDA
>NZ_CP047147.1|WP_003949403.1|3597060_3597297_+|30S-ribosomal-protein-S18
MAKPPVRKPKKKVCAFCKDKVTYVDYKDTNMLRKFISDRGKIRARRVTGNCTQHQRDVATAVKNSREMALLPYTSTAR
>NZ_CP047147.1|WP_003949404.1|3597315_3597762_+|50S-ribosomal-protein-L9
MKIILTHEVSGLGAAGDVVDVKDGYARNYLVPRGFAIRWTKGGEKDVEQIRRARKIHEIATIEQANQVKAELEGVKVRLSTRSGEAGRLFGSVTQADIAAAISAAGGPKVDKRRIELDAPIKSLGAHSASVRLHPEVAAKVNVEVVAA
>NZ_CP047147.1|WP_010644352.1|3597899_3599237_-|MATE-family-efflux-transporter
MTKAAPQAKHHRRQHDREIVALAVPAFGALVAEPLFVMADSAIIGHLGTAQLAGLAVASALLTTAVSIFVFLAYATTGAVARRVGAGELSAAIRQGMDGIWLALLLGAAVIAVVLPTAPALIDLFGASETAAPYAVTYLRISSFGIPAMLVVLAATGVLRGLQNTRTPLYVAIGGFVANAILNVVLVYGAGLGIAGSAWGTVIAQCGMAAVYLVVVVRGARKHGASLRPDAAGIRASAQAGAPLLVRTLSLRAVLMIATAVAARLGDTEIAAHQIILSLWSLLAFAMDAIAIAGQAIIGRYLGAGDSAGAKAVCRRMVEWGIGSGIVLGVLVIVSRPLFIPLFTSDGAVKDAALPALVVVALCQPLSGIVYVLDGVLMGAGDGPYLAWAMLLTLAIFTPFALLIPSWGGGLTAVWGAMTLMMATRAVTLGLRTRSGRWLVTGASR
>NZ_CP047147.1|WP_003949406.1|3599706_3601176_+|replicative-DNA-helicase
MSISEPLDDPWAADAGPGDRLPASRRRGKGNDGGRDRDGDNWEGGGATAFERVPPQDLDAEQSVLGGMLLSKDAIADVVEILKGNDFYRPAHETIYQAILDLYAKGEPADPITVAAELTKRGEITKVGGAPYLHTVVQTVPTAANAEYYAEIVHERAVLRRLVEAGTKITQMGYAADGDVDEIVNSAQAEIYAVTEQRTSEDYLPLGDIMEGALDEIEAIGSRSGEMTGVPTGFTDFDSLTNGLHPGQMIVIAARPAMGKSTLALDFARAASIQNNLPSVVFSLEMGRNEIAMRLLSAEARVALHHMRSGTMTDEDWTRLARRMPDVSAAPLYIDDSPNLSMMEIRAKCRRLKQRNDLKLVVIDYLQLMQSGGSKRAESRQQEVSDMSRNLKLLAKELEIPVIALSQLNRGPEQRTDKKPMVSDLRESGSIEQDADMVILLHREDAYEKESPRAGEADLIVAKHRNGPTATITVAFQGHYSRFVDMAHG
>NZ_CP047147.1|WP_018470259.1|3601200_3601770_-|deaminase
MRKLIYGMNLSLDGYIAAPGDDIGWSGPPSDELFQWWLDQEQASGLTLYGRKLWETMSAYWPTGDQQPDATPAEIAFARNWRSTPKVVFSSTLDGPLDWNTRLVTGDALAEITRLKAGDGAPLQIGGATLAAAAMRAGLIDEYAIATHPVLIGGGTPFFGPLDSWVNLNLLETRTFPGGTVLTRYETRR
>NZ_CP047147.1|WP_159312636.1|3601926_3602469_+|sugar-O-acetyltransferase
MADDRLMRIHSDEFRAMSERVLRATELTSRLNVLPFEDEAGKAELFERILGRPLPARTTIYPPFYTDHGLHLELAERVFINQNCTFLDYAGIRLGERVMVGPKATFITLGHPVDPGERQEWLSGGPIDVAENVWIGAGATILPGVSIGRDAVVAAGAVVAEDVPPATLVTGPKATVNRQW
>NZ_CP047147.1|WP_159312637.1|3602581_3603730_+|serine-hydrolase
MGTVEIGGWADEGFGGVADVFRENFEVFGELGTAVSVRVGGRPVVELWGGIADERSGRLWDQETVVPVFSCAKGLVSICAHLLAQQGRLDLDAPVAAYWPEFAAEGKERITTRMVLGHRAGVPVLDRTVSFGEITEWTPVVRAIEEQRPLWEPGEAYEYHGHVFGFLVGEVVRRITGLTPGRFFREAIGEPLGLRAWIGLPAAERGQLARLVEAEGRPAGDPQSLLMRIVTMNGALVFPGLDEPHGFNDPELLGTELPGAGAVASASGLAALYGAAVTGLDGGPRLLSEETLTDAVREVSAGPTWQGYDLGQRWGSGFLLDSERPRPMMGARSFGNDGAGGQFAFGDDEFGVGFAYVANRMIGHGDDRANRLITALRESLKA
>NZ_CP047147.1|WP_159312638.1|3604042_3605446_+|serine-hydrolase
MTTHETPEDLSLLPATRRALRHRLARAQSESRVPSLVAGVTRDGEVIWEGALSALEGVEADGDTQYRIGSISKTFTAVLVMRLRDEGLLELTDPLEKHLPGTGAGRATVADLLSHTGGLAAEAPGEWWERSPGTLRPELADVLGEEPHRHPVGRVHHYSNPGYTLLGALVEEVRGEPWEKVLRAEVLEPLGLTRTSYAPQAPYAQGWAVHPWADTLLPEPAHDLGRMAPAGQLWSTTRDLLRFAAFLVQGDDAVLGAASVREMRTPAAPSLPGAQESAYGLGTQVLSVGGGITLTGHMGSLPGYLAALLTREDEGLAAVVLANTTSGPLIGSLAAELIGIVAEAEPSMPRLWRPMAEADPQVLELAGAWYWGVTPYGLHYGADGGVELRPLKGVGRAARFVPAGDGTWRGLDGYFLGETLRPVRDAEGMVTHLDLGSFVFTREPYAPDSVVPGGVDAKGWRAAGELG
>NZ_CP047147.1|WP_159312639.1|3605602_3606106_-|GNAT-family-N-acetyltransferase
MDHSQDAPQQDSSQGSSGDTLLIRRAEASDVAAIVAMLADDPLGATRESPDDLTPYLAANTRLAADPNQHLVVAERAGKVVGTLQLTLIPGLSRRAATRSLIEGVRVHADERGSGLGTLLIEWAVETSRAEGCQLVQLTSDATREDAHRFYERLGFVASHVGFKLQL
>NZ_CP047147.1|WP_008408220.1|3606156_3606615_-|MarR-family-transcriptional-regulator
MTATDPALTALAQSWCALSLLHGRIETHVERALQSGHGLSTREYSLLDVLSRQHDGEGGHLQMKQVADAVVLSQSATTRLVSRLEDRGLLSRYLCPTDRRGIYTDVTPAGKALLDEARPTNDTALREALDTAAQNPELAPLVQAVETLRTPA

Crispr_ID: NZ_CP047147_18

• CRISPR_ID: NZ_CP047147_18
• CRISPR_location: 3736002-3736170
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers
• Cas_protein_info: csa3

Consensus repeat of NZ_CP047147_18

Consensus_repeat	Method
CAGCCCGGCCGGCGCTTGAGGCCA	PILER-CR

spacers of NZ_CP047147_18

>18.1|3736026|55|NZ_CP047147|PILER-CR
GGGCGGGGCTGGGCTGCGCCCCGAACTGGCCGCCCCTCGGCCGTCCGGTCAAAGA
>18.2|3736105|52|NZ_CP047147|PILER-CR
TCTGCGGGCTTCGTCCCGACCTGAGCTGCGCCCCCGTCCCGGTTGCCCACGG

CRISPR arrays and Neighbor proteins around NZ_CP047147_18

CRISPR arrays

The CRISPR arrays of NZ_CP047147_18

>merge|NZ_CP047147|18|3736002-3736170|PILER-CR
CGCGGGCCGGGCTGGGGCGGGGCTGGGCTGCGCCCCGAACTGGCCGCCCCTCGGCCGTCCGGTCAAAGATGGCCTCAAGCGCCGGCCGGGCTGTCTGCGGGCTTCGTCCCGACCTGAGCTGCGCCCCCGTCCCGGTTGCCCACGGTGGCCTCAAGCGCCGGCCAGGCTG

>NZ_CP047147|18|3|3736002-3736170|PILER-CR
CGCGGGCCGGGCTGGGGCGGGGCT	GGGCTGCGCCCCGAACTGGCCGCCCCTCGGCCGTCCGGTCAAAGATGGCCTCAAG
CGCCGGCCGGGCTGTCTGCGGGCT	TCGTCCCGACCTGAGCTGCGCCCCCGTCCCGGTTGCCCACGGTGGCCTCAAG
CGCCGGCCAGGCTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_159312679.1|3722572_3723091_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|197666
NZ_CP047147.1|WP_159313921.1|3727656_3729315_+|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|223732
NZ_CP047147.1|WP_003949534.1|3746383_3748633_+|phosphoribosylformylglycinamidine-synthase-subunit-PurL	unknown	unknown	gnl|CDD|234921
NZ_CP047147.1|WP_008413354.1|3727034_3727379_-|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl|CDD|378915
NZ_CP047147.1|WP_003949519.1|3729418_3729751_+|helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|197713
NZ_CP047147.1|WP_003949525.1|3737589_3739083_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_003949514.1|3723119_3723530_+|VOC-family-protein	unknown	unknown	gnl|CDD|319924
NZ_CP047147.1|WP_078858062.1|3726113_3727022_+|Dyp-type-peroxidase	unknown	unknown	gnl|CDD|367887
NZ_CP047147.1|WP_003949529.1|3742399_3743209_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|223912
NZ_CP047147.1|WP_018894829.1|3740292_3740958_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NZ_CP047147.1|WP_037845302.1|3734087_3735863_+|hypothetical-protein	unknown	unknown	gnl|CDD|320687
NZ_CP047147.1|WP_008409762.1|3743205_3744189_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
NZ_CP047147.1|WP_159312680.1|3723583_3725974_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|223256
NZ_CP047147.1|WP_003949522.1|3732377_3733652_+|phosphoribosylamine--glycine-ligase	unknown	unknown	gnl|CDD|234856
NZ_CP047147.1|WP_003949531.1|3744725_3745043_-|Lsr2-family-protein	unknown	unknown	gnl|CDD|378714
NZ_CP047147.1|WP_008409760.1|3745428_3745680_+|phosphoribosylformylglycinamidine-synthase-subunit-PurS	unknown	unknown	gnl|CDD|235659
NZ_CP047147.1|WP_159312681.1|3730211_3732317_+|DNA-polymerase-III-subunit-gamma-and-tau	unknown	unknown	gnl|CDD|236090
NZ_CP047147.1|WP_129845642.1|3740967_3742323_-|histidine-kinase	unknown	unknown	gnl|CDD|226951
NZ_CP047147.1|WP_159312682.1|3739177_3740080_+|phosphoribosylaminoimidazolesuccinocarboxamide-synthase	unknown	unknown	gnl|CDD|237571
NZ_CP047147.1|WP_003949533.1|3745676_3746387_+|phosphoribosylformylglycinamidine-synthase-subunit-PurQ	unknown	unknown	gnl|CDD|235140

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP047147.1|WP_003949519.1|3729418_3729751_+|helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	4.6e-17	57.2	0.5

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_159312679.1|3722572_3723091_+|helix-turn-helix-domain-containing-protein	gnl|CDD|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	1.60071e-26
NZ_CP047147.1|WP_159313921.1|3727656_3729315_+|STAS-domain-containing-protein	gnl|CDD|223732	COG0659, SUL1, Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism].	1.67074e-117
NZ_CP047147.1|WP_003949534.1|3746383_3748633_+|phosphoribosylformylglycinamidine-synthase-subunit-PurL	gnl|CDD|234921	PRK01213, PRK01213, phosphoribosylformylglycinamidine synthase subunit PurL.	0
NZ_CP047147.1|WP_008413354.1|3727034_3727379_-|nuclear-transport-factor-2-family-protein	gnl|CDD|378915	pfam12680, SnoaL_2, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	2.30762e-08
NZ_CP047147.1|WP_003949519.1|3729418_3729751_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|197713	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor.	9.07104e-14
NZ_CP047147.1|WP_003949514.1|3723119_3723530_+|VOC-family-protein	gnl|CDD|319924	cd07263, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	8.59344e-39
NZ_CP047147.1|WP_078858062.1|3726113_3727022_+|Dyp-type-peroxidase	gnl|CDD|367887	pfam04261, Dyp_perox, Dyp-type peroxidase family. This family of dye-decolourising peroxidases lack a typical heme-binding region.	1.29902e-90
NZ_CP047147.1|WP_003949529.1|3742399_3743209_-|ABC-transporter-permease	gnl|CDD|223912	COG0842, COG0842, ABC-type multidrug transport system, permease component [Defense mechanisms].	9.65729e-11
NZ_CP047147.1|WP_018894829.1|3740292_3740958_-|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	5.82065e-60
NZ_CP047147.1|WP_037845302.1|3734087_3735863_+|hypothetical-protein	gnl|CDD|320687	cd07328, M48_Ste24p_like, M48 Ste24 endopeptidase-like, integral membrane metallopeptidase. This family contains peptidase M48-like proteins that are as yet uncharacterized, but probably function as intracellular, membrane-associated zinc metalloproteases; they all contain the HEXXH Zn-binding motif, which is critical for Ste24p activity. They likely remove the C-terminal three residues of farnesylated proteins proteolytically and are possibly associated with the endoplasmic reticulum and golgi.	1.80294e-06
NZ_CP047147.1|WP_008409762.1|3743205_3744189_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	6.84452e-97
NZ_CP047147.1|WP_159312680.1|3723583_3725974_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|223256	COG0178, UvrA, Excinuclease ATPase subunit [DNA replication, recombination, and repair].	0
NZ_CP047147.1|WP_003949522.1|3732377_3733652_+|phosphoribosylamine--glycine-ligase	gnl|CDD|234856	PRK00885, PRK00885, phosphoribosylamine--glycine ligase; Provisional.	0
NZ_CP047147.1|WP_003949531.1|3744725_3745043_-|Lsr2-family-protein	gnl|CDD|378714	pfam11774, Lsr2, Lsr2. Lsr2 is a small, basic DNA-bridging protein present in Mycobacterium and related actinomycetes. It is a functional homolog of the H-NS-like proteins. H-NS proteins play a role in nucleoid organisation and also function as a pleiotropic regulator of gene expression.	5.88457e-48
NZ_CP047147.1|WP_008409760.1|3745428_3745680_+|phosphoribosylformylglycinamidine-synthase-subunit-PurS	gnl|CDD|235659	PRK05974, PRK05974, phosphoribosylformylglycinamidine synthase subunit PurS; Reviewed.	2.46331e-40
NZ_CP047147.1|WP_159312681.1|3730211_3732317_+|DNA-polymerase-III-subunit-gamma-and-tau	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	0
NZ_CP047147.1|WP_129845642.1|3740967_3742323_-|histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	3.74645e-37
NZ_CP047147.1|WP_159312682.1|3739177_3740080_+|phosphoribosylaminoimidazolesuccinocarboxamide-synthase	gnl|CDD|237571	PRK13961, PRK13961, phosphoribosylaminoimidazole-succinocarboxamide synthase; Provisional.	0
NZ_CP047147.1|WP_003949533.1|3745676_3746387_+|phosphoribosylformylglycinamidine-synthase-subunit-PurQ	gnl|CDD|235140	PRK03619, PRK03619, phosphoribosylformylglycinamidine synthase subunit PurQ.	1.30918e-143

Protein sequences

>NZ_CP047147.1|WP_037845302.1|3734087_3735863_+|hypothetical-protein
MARAGAVAVLRVRGRAVALALLPAALAVVLLAGAPTGVLTGPVWDAARALVSAVAVLVLLAAAGLALAVARARPAVSPTVPVSEDSAPDLHRLVRDLADRLEVPAPSAIALTPDCDSWLEDRSHPALGADAVRPAHGQEPPAPVLVIGSPFLWWMRVAELRAVLAPVVAGTGPSAQPDIIAARRFVRGLDAAAALGTEPGRGPLARLVLGGTARLARLLLHACREEAAEMERAVAATSSERAKAVDYGLRIAAQEQVGLAYAGWDRLLNRVALPAWRIGRWPARLDAGVVAALTELSRRDRLADDFTTRLGERPACDLLEEPGTIDESTSLLAARLFHGEPAGSEPQWLPVDWEGYADEVVDRTWRTEAARLHRVLDGLGVPASEPGGATLARVLEHLAVPAGVPAAEPGGLPELTEAELATASDDELALRTGVDIGGEAAGRAATVPQPGGEVRRRVAERAEELAEALAAEVARDEARVPAGVPAPVGQGADETLSAGGRLPLCPLQPPRTGRELLAGHVAAMVCCSAMDTAGALPGLDWLDGPVLLVQGRRASDLAVRVTALVDQGDGGPLLTWVHQTGIRPDKPVRLV
>NZ_CP047147.1|WP_003949522.1|3732377_3733652_+|phosphoribosylamine--glycine-ligase
MKVLVIGSGAREHALCRSLSLDPDVTALYCAPGNAGIAEVAELHPVDALDGAAVARLATGLGADLVVVGPEAPLVAGVADAVRVAGIDCFGPSAEAARLEGSKAFAKDVMAGAGVPTARSYVCTTAAEIDTALDAFGAPYVVKDDGLAAGKGVVVTEDVDEAREHALNCVSAGGGRVVVEEFLDGPEVSLFAVTDGRTVVPLQPAQDFKRALDGDQGPNTGGMGAYSPLPWADPKLVDEVLETVLQPTVDELRRRGTPFSGLLYAGLAITSRGIRVIEFNARFGDPETQVVLARLRTPLAGVLRAAADGTLAALPPLRWSEEAAVTVVVASHNYPGTPRTGDPVEGLAEVAELDAPAAYVLHAGTRQDGDAVLSAGGRVLSVTATGADLTEARDRAYTAVARIRLDGSQHRSDIAARVAVEERG
>NZ_CP047147.1|WP_159312681.1|3730211_3732317_+|DNA-polymerase-III-subunit-gamma-and-tau
MSSLALYRRYRPESFAEVIGQEHVTDPLQQALRNNRVNHAYLFSGPRGCGKTTSARILARCLNCEQGPTPDPCGTCQSCQDLARNGPGSIDVIEIDAASHGGVDDARDLREKAFFGPASSRYKIYIIDEAHMVTSAGFNALLKVVEEPPEHLKFIFATTEPEKVIGTIRSRTHHYPFRLVPPGTLREYLAEVCGKEGSRVEDGVLPLVVRAGAGSVRDSMSVMDQLLAGAGEDGVTYAMATALLGYTDGSLLDSVVDAFAAGDGAAAFEVVDRVVEGGNDPRRFVADLLERLRDLVILAAVPDAAEKGLIDAPADLVERMQAQASVFGAAELSRAADLVNEGLTEMRGATSPRLQLELICARVLLPAAYDDERSTLARLERLERSGPPAQAAAPLAPQAYAPAQPQVPQAPPAAAPAPAPQQSAPPAPAPDAPPADAAPARPGAWPGSAAPGSGAPAPAARRPGGWPTAGAGGGPAPQQAEPQGPGRPQGQPQPQAAPATPPPGAVDARALWPNVLEAVKNRRRFTWILLSQNAHVAGFDGTTLQLGFLNAGARDNFASSGSEDVLKQALGEEFQVNWKIETVIDASGGQGPATPPGGGGGGGWGQAPAQPRPAAPAPAPAPAPPQPGPAAPPAPAPASQTPPAPQREQRPPAPEPPRRTTSIEDDIPEEDDPDLDESALSGHDLIMRELGATVVEEYTNE
>NZ_CP047147.1|WP_003949519.1|3729418_3729751_+|helix-turn-helix-transcriptional-regulator
MSTPLYQLKAEFFKTLGHPVRIRVLELLSRREHAVSELLSDIGVEPAHLSQQLAVLRRANLVVPRREGSAVHYSLTNPDVAELLRVARTILSGVLTDQAELLAGLRADES
>NZ_CP047147.1|WP_159313921.1|3727656_3729315_+|STAS-domain-containing-protein
MRSLLPTRADFAAMTRAPRRDLLAGLTVAIVALPLALGFGVSSGLGAEAGLATAVVAGALAALFGGSSLQVSGPTGAMTVVLVPIVAQYGPGGVLTVGLLAGVLLLALAVLKAGRYMRYVPAPVVEGFTLGIACVIGLQQVPNALGVTAPEGDSVLMVTWHAVEEFVRAPNWTATGLALGVAAVMLLGARWRPAVPFSIVAVVAATAAAQFFHLDGAAPIGALPSGLPAPSLDFLELSALGSLLAPALAVAALAALESLLSATVADGMTTGQKHDPDRELFGQGVANLAAPLFGGVPATAAIARTAVNVRSGAGSRLAALTHAAVLAVIVFAAAPLVSKIPLAALAGVLIATAVRMVEAGALRAMVRSTRSDAVVLVLTAVATLVLDLVLAVVIGLVVAGALALRAVALQARIDRTDAPSEPSAVHSDAEHAPPSEHIATYRVDGPLFFAGAHRVLLELSEVAGVRVVILRLARVTTMDATGALALKEAVEDLGRRGIAVLACGIRPAHRRTLASVGALEALRDREYATGSEALAAAHAHLGRTGPLPAGTA
>NZ_CP047147.1|WP_008413354.1|3727034_3727379_-|nuclear-transport-factor-2-family-protein
MASTEQVAERFHAALTAADADGLRGVLADEVTFEGPVATASGVAECVAGLVEMGKMISGDQVEVRLADGGNVLTWSTVRAGGGPGRPTVTWLRVDGERITAIRTVFDARGTGGR
>NZ_CP047147.1|WP_078858062.1|3726113_3727022_+|Dyp-type-peroxidase
MDAPLSAAAGFLVLVVKDGEEAAATVRSVVAGTDDLIKDITIRANGAMFTCNVGISHHGWPRLTGKPLPKELRPFREIKGEKHTAVATPGDLLYHLRAASPDLIVEFEKILLEAFGDSVTAVDDVTGFRYFDGRDLLEFADGTANPDGAALPAATLVGDEDPAYAGGSYVVVQKYLHDLSAWRAQTTGTQEEIIGRTKFDNVEKPDATEGQKSHKTLCTIQDADGEHDILRDNMPFAHPGTGEYGTYFIGYSRHLWVTEKMLERMFLGDPPPLHDRILDYSRAVTGVTFFCPARAFLAALGD
>NZ_CP047147.1|WP_159312680.1|3723583_3725974_+|ATP-binding-cassette-domain-containing-protein
MTRATRQDAPSAAPHAADHHDLIRVHGARENNLKDVSIEIPKRRLTVFTGVSGSGKSSLVFDTIAAESQRLINETYSAFLQGFMPTLARPEVDVLEGLTTAIIVDQQRLGADPRSTAGTATDANAMLRILFSRLGDPHIGSPNAYSFNVPSVRAHGAITVERGNAKTVRQSFTRTGGMCPHCEGRGTVSDIDLTQLYDDSKSISEGAFTIPGWKSDSWWTVRLYADSGFLDPDKPIRDFTEQEMRDFLYREPTKVKVEGTNLTYEGLIPKIQKSFLSKDREGMQPHIRAFVDRAVTFTACPECQGTRLSEAARSSRIGELNIADACALQITDLADWVATLDEPSVAPLLAALRHTLDSFVEIGLGYLSLDRPAGTLSGGEAQRVKMIRHLGSSLTDVTYVFDEPTIGLHPHDIERMNGLLLRLRDKGNTVLVVEHKPETIAIADHVVDLGPGAGTGGGTISFEGTVAGLRASDTLTGRHLDDRATLKKEVRKPTGTLEIRGADRHNLQDVDVDIPLGVLTVVTGVAGSGKSSLIHGSIPRSDEVVSVDQSPIRGSRRSNPATYTGLLDPIRKAFAKANGVKPALFSANSEGACPNCKGAGVVYTDLGMMAGVSATCEECDGKRFEASVLEHHLGGKDISEVLAMPVTEAEEFFREGEARTPAAHRVLTRLADVGLGYLTLGQPLTTLSGGERQRLKLATHMADKGGTYVLDEPTTGLHLADVDQLLALLDRLVDSGKSVIVIEHHQAVMAHADWIIDLGPGAGHDGGRVVFEGTPAELTENRGTVTGEHLAAYVGG
>NZ_CP047147.1|WP_003949514.1|3723119_3723530_+|VOC-family-protein
MHLTVHASFLPHNDPEAALAFYRDLLGLEVRDDVGYGGMRWITVGPPGGAGSAIVLLPPGADPGVTEDERRTIDAMMAKGTYGGILLATPDLTTTFEKLVAGDAEIVQEPTDQPYGVRDCAVRDPAGNLIRIQERR
>NZ_CP047147.1|WP_159312679.1|3722572_3723091_+|helix-turn-helix-domain-containing-protein
MSTSPPPAPHLGDLVLLRRVRDRIDREYARPLDVEALAQGVNMSAGHLSRQFRLAYGEPPYSYLMTRRIERAMALLRRGDLNVTEVCFAVGCSSLGTFSSRFTELVGVPPSVFRERQDLAGQNIEGMPACVAKQVTRPVRKARPPRGSALGGEPAGGAEPVRNREARTGRPA
>NZ_CP047147.1|WP_003949525.1|3737589_3739083_+|hypothetical-protein
MGSGHIRRWESGAYAHAVSDPFGQGPVPWLRGSENYFDDTGQVVPWYVEHAPAPGASGPRIPPPRPGGGPRTADDVDQQIKGFASAGAVAPGESIDFHITVNPPQQFSVDVYRIGHYGGDGASKITTSPRLSGIVQPPPLTADRTVSCHHWWLSWRLQVPTLWSIGAYVAVLTTADGRYRSHVPFTVRDSHPADLLLVLPDVTWQAYNLYPEDGRTGASLYHAWDESGKLLGEEDAAVTLSFDRPYAGAGLPLHVGHAYDFIRWAERYGYDLAYADTRDLHSGRIDPTRYRGLVFPGHDEYWSVPMRNTVELARDHGTSLVFLSANTMYWKVELSPSASGVPDRMLICRKRRGPGRPALWREVERAEQQLLGIQYAGRVPEPHPMVVRNASHWLWEATGAHEGDELPGMVAGEADRYFPRTRLPEHDSRILLAHSPYRDHEGVKRHQETSLYRAPSGALVFASGTFAWSPALDRPGHVDERVQRATANLLDRICKRD
>NZ_CP047147.1|WP_159312682.1|3739177_3740080_+|phosphoribosylaminoimidazolesuccinocarboxamide-synthase
MSGFVEKPEPVEVPGLVHLHTGKVRDLYQNEAGDLVMVASDRISAYDWVLPTEIPDKGRVLTQLSLWWFDQLADLVPNHVLSTTLPEGAPADWKGRTLVCKSLEMAPVECVARGYLTGSGLVEYEESRTVCGLALPPGLVNGSELPAAIFTPATKAAVGDHDENVSYEEVARLVGPETAAELRQTTLAVYSRALDVARERGLILADTKFEFGHDADGTLILADEVLTPDSSRYWPADTWEPGRAQPSFDKQFVRDWLTSEASGWDRHAEQPPPALPEEVVERTRAKYIEAYERLTGVSWG
>NZ_CP047147.1|WP_018894829.1|3740292_3740958_-|response-regulator-transcription-factor
MTEQSPEPPAPTGPAPSGGAPVRVLLADDEHLIRGAVAALLALEDDLVVVAEAATGPEALAMARAHRPDVAVLDLQMPGADGVAVATSLRDELPACRVMIVTGHGRPGNLKQALAAGVRGFVPKTVSAQRLAELVRSVHAGNRYIDPELAADAIAAGDSPLTAREAEVLELAADGAPVAEIAERAALSPGTVRNYLSSAVTKLGAENRHSAVRLARERGWV
>NZ_CP047147.1|WP_129845642.1|3740967_3742323_-|histidine-kinase
MTGTGDHEDAATYGATAQAAIRRPGRWWGRKGTAAKVESYTRISFHLFPVAQLVTALLSLTPVPARSALPVAGALLVHVVLGLRLTGQALDWVAGRRARPRRLLFAYMACGFAGAAIAALVLVKLPDDPPATYYTACVGTYVLFLAFSCGLGVLALRTHRQSLVAVAVATFGGWLLGSALLPAPAAAALALSTLLSAGGLTLASRFSIWLLQAVYELDEARHTRARLAVAEERLRFGRDLHDVLGRNLSVIALKSELAVQLARRERPEAVEQMAEVQRIAQESQREVREVVRGYREADLYTELLGARGVLSAAGITCTVTGTPTGLPRPVQAALAWVVREAVTNVLRHGNAAHCRIALTVVPAGPRAEGRPAVAELTVENDGVPSASDGSTGGHGLAGLRERLAAEQGTLEAGPAGKSAFRLVARVPVPADEVAESGVPGETAERARQELE
>NZ_CP047147.1|WP_003949529.1|3742399_3743209_-|ABC-transporter-permease
MSAVTTPPAPAGQEQRTRPLGRLAALARAELALLVRSKGVMFAALFVPFVLPFSVAQTVDDDTLKGTGLTLGLVLLPGAIGFSLLFAVYSSLVTIYATRRDELVLKRLRTGELRDNEILAGTAVPSIIIGLAQSAVLIVAVTALLDIGAPKAPHLAVLGILVGIVLMVVLAALTSALSRTAESAQVMAMPVLLVLMLGSGMVVPLEVFPDSLASVCERLPLTGAMALIRGGWTGELSGGDILTAAVTSLAWIALSLFAVRRWFRWEPRR
>NZ_CP047147.1|WP_008409762.1|3743205_3744189_-|ABC-transporter-ATP-binding-protein
MNTEDHVIDVTDLRRVYGGGFEAVRGVSFTVGRGELFALLGTNGAGKTSTLEVLEGLARPASGRVRVLGHDPFGERDAVRPRIGVMLQDGGFPSELTVRETLRMWAGCTSGARPIGEALEMVGLGKRADVRVKVLSGGEKRRLDLALALLGRPEVLFLDEPTTGLDAEGRQDTWSLVRELRAEGTTVLLTTHYLEEAEALADRLAILHEGRIASEGTVEDVVSAQPSRITFDLPDGWFPGDLPPLDQLGVTGHSHDGRTVRLMTQNLQQAATSLLLWARDAGVSLGSLDVRAASLEEAFLHIAREADGRGDSATAAASLDPRKETAA
>NZ_CP047147.1|WP_003949531.1|3744725_3745043_-|Lsr2-family-protein
MAQRVVVTLFDDIDGGEASETVAFGLDGTSYEIDLNRTNAEKLRETLEPYLRAGRKRSASGRAYQRTSVAADPAAVRAWARSHQMDVPPRGRIPKRVYEAFEQAN
>NZ_CP047147.1|WP_008409760.1|3745428_3745680_+|phosphoribosylformylglycinamidine-synthase-subunit-PurS
MARVVVDVMLKPEILDPQGQAVQRALPRLGFEGISDVRQGKRFELEVDGPVDDAALARIHELAETFLANTVIENFTVKVEEEK
>NZ_CP047147.1|WP_003949533.1|3745676_3746387_+|phosphoribosylformylglycinamidine-synthase-subunit-PurQ
MTAGPTPAARSNTRVGVVTFPGSLDDRDTQRAIRLAGAEAVPLWHKDKSLQQVDAVVLPGGFSYGDYLRAGAISRFSPLMEKVIDGARAGLPVLGICNGFQVLTEAHLLPGAMLGNDHLHFICRDQKLRVENTATAWTGDYVAGQEIHIPLKNMDGRYVADSRTLDMLEAEGRVAFRYLDVNPNGSLRDIAGITNEAGNVVGLMPHPEHAVEPLVGSGRTDGLPFFTSIIKKLVSA
>NZ_CP047147.1|WP_003949534.1|3746383_3748633_+|phosphoribosylformylglycinamidine-synthase-subunit-PurL
MSLDTVKHATDTPDTEQPWAELGLKEDEYARVREILGRRPTGAELAMYSVMWSEHCSYKSSKVHLRQFGEKAPQSDAMLVGIGENAGVVDVGQGYAVTFKVESHNHPSYVEPYQGAATGVGGIVRDIIAMGARPVAVVDPLRFGAADHPDTRRVLPGVVAGIGGYGNCLGLPNIGGEVVFDSCYQGNPLVNAGAIGVMRHEDIHLAKASGTGNKVILYGARTGGDGIGGASILASETFDDAKPSKRPAVQVGDPFQEKLLIECTLEAFAEKLVVGIQDLGAAGLSCATSELASNGSGGMRVTLDDVPLRDSTLSPEEILMSESQERMCAVVEPEKVDRFLAICEKWDVIATVIGEVTDGDRLEIFWHGEKIVDVDPRTVAHDGPVYERPLARPEWQDALQADDAGKLPRPATGGELKEQVLALLSSPNQASKSWITSQYDHFVQGNTVLAQPEDAGMIRVDEESGLGVAIATDGNGRFAKLDPYHGAQLALAEAYRNVATTGAKPLAVSDCLNFGSPEDPAVMWQFAEAIRGLADACQILGTPVTGGNVSLYNQTGDVAIHPTPVVAVLGVIDDVARRTPVAFAEEGQLLYLLGETREEFGGSAWSQVVHDHLGGLPPRVDLERERLLADILISASRDGMVDAAHDLSDGGLVQAVAESCLRGQKGARLVVPDGLDAFTFLFSESAGRVVVSVPRSEELRFTDMCGARGLPATRIGVVDGDALEVQGEFTLSLREVREAHEGTIEALMA

Crispr_ID: NZ_CP047147_19

• CRISPR_ID: NZ_CP047147_19
• CRISPR_location: 3736260-3736666
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 5 spacers
• Cas_protein_info: csa3

Consensus repeat of NZ_CP047147_19

Consensus_repeat	Method
AGCCCGGCCGGCGCTTGAGGCC	PILER-CR

spacers of NZ_CP047147_19

>19.1|3736282|55|NZ_CP047147|PILER-CR
GGGTGGGGGTTCCTCTCTCTTGTCCCTGCTGACCGCGACCGTGCCGCTCACCGAT
>19.2|3736359|55|NZ_CP047147|PILER-CR
TGGTTGTGGCGGGGCTCCGCCCCGATCTGCTTGTCTCGACCGTGCCGGTCACGGC
>19.3|3736436|62|NZ_CP047147|PILER-CR
GGGATGCGGTGTGGCTGGGCTCCGCCCGTCCGTGCCCGTCGTGACCCTGGGGGCCACTGACT
>19.4|3736520|63|NZ_CP047147|PILER-CR
GGGGTTTGGTGTGGTTGGGCTCCGCCCCTGCGTGCCCGCCCGTGACCCTGCGGGTCACTGATT
>19.5|3736605|42|NZ_CP047147|PILER-CR
GTTGGTTGCGGGGCTCCGTCTCGACCGTGCCGGTCAAAGACT

CRISPR arrays and Neighbor proteins around NZ_CP047147_19

CRISPR arrays

The CRISPR arrays of NZ_CP047147_19

>merge|NZ_CP047147|19|3736260-3736666|PILER-CR
CCTCAAGCGCCGGACGGGCTGGGTGGGGGTTCCTCTCTCTTGTCCCTGCTGACCGCGACCGTGCCGCTCACCGATGGCCTCAAGCGCCGGCCGGGCTTGGTTGTGGCGGGGCTCCGCCCCGATCTGCTTGTCTCGACCGTGCCGGTCACGGCGGCCTCAAGCGCCGGCCGGGCTGGGATGCGGTGTGGCTGGGCTCCGCCCGTCCGTGCCCGTCGTGACCCTGGGGGCCACTGACTGGCCTCAATCGCCGGCCGGGCTGGGGTTTGGTGTGGTTGGGCTCCGCCCCTGCGTGCCCGCCCGTGACCCTGCGGGTCACTGATTGGCCTCAATCGCCGGCCGGGCTGTTGGTTGCGGGGCTCCGTCTCGACCGTGCCGGTCAAAGACTGGCCTCAATCGCCGGCCGGGCT

>NZ_CP047147|19|4|3736260-3736666|PILER-CR
CCTCAAGCGCCGGACGGGCTGG	GTGGGGGTTCCTCTCTCTTGTCCCTGCTGACCGCGACCGTGCCGCTCACCGATGG
CCTCAAGCGCCGGCCGGGCTTG	GTTGTGGCGGGGCTCCGCCCCGATCTGCTTGTCTCGACCGTGCCGGTCACGGCGG
CCTCAAGCGCCGGCCGGGCTGG	GATGCGGTGTGGCTGGGCTCCGCCCGTCCGTGCCCGTCGTGACCCTGGGGGCCACTGACTGG
CCTCAATCGCCGGCCGGGCTGG	GGTTTGGTGTGGTTGGGCTCCGCCCCTGCGTGCCCGCCCGTGACCCTGCGGGTCACTGATTGG
CCTCAATCGCCGGCCGGGCTGT	TGGTTGCGGGGCTCCGTCTCGACCGTGCCGGTCAAAGACTGG
CCTCAATCGCCGGCCGGGCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_159312679.1|3722572_3723091_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|197666
NZ_CP047147.1|WP_159313921.1|3727656_3729315_+|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|223732
NZ_CP047147.1|WP_003949534.1|3746383_3748633_+|phosphoribosylformylglycinamidine-synthase-subunit-PurL	unknown	unknown	gnl|CDD|234921
NZ_CP047147.1|WP_008413354.1|3727034_3727379_-|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl|CDD|378915
NZ_CP047147.1|WP_003949519.1|3729418_3729751_+|helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|197713
NZ_CP047147.1|WP_003949525.1|3737589_3739083_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_003949514.1|3723119_3723530_+|VOC-family-protein	unknown	unknown	gnl|CDD|319924
NZ_CP047147.1|WP_078858062.1|3726113_3727022_+|Dyp-type-peroxidase	unknown	unknown	gnl|CDD|367887
NZ_CP047147.1|WP_003949529.1|3742399_3743209_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|223912
NZ_CP047147.1|WP_018894829.1|3740292_3740958_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NZ_CP047147.1|WP_037845302.1|3734087_3735863_+|hypothetical-protein	unknown	unknown	gnl|CDD|320687
NZ_CP047147.1|WP_008409762.1|3743205_3744189_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
NZ_CP047147.1|WP_159312680.1|3723583_3725974_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|223256
NZ_CP047147.1|WP_003949522.1|3732377_3733652_+|phosphoribosylamine--glycine-ligase	unknown	unknown	gnl|CDD|234856
NZ_CP047147.1|WP_003949531.1|3744725_3745043_-|Lsr2-family-protein	unknown	unknown	gnl|CDD|378714
NZ_CP047147.1|WP_008409760.1|3745428_3745680_+|phosphoribosylformylglycinamidine-synthase-subunit-PurS	unknown	unknown	gnl|CDD|235659
NZ_CP047147.1|WP_159312681.1|3730211_3732317_+|DNA-polymerase-III-subunit-gamma-and-tau	unknown	unknown	gnl|CDD|236090
NZ_CP047147.1|WP_129845642.1|3740967_3742323_-|histidine-kinase	unknown	unknown	gnl|CDD|226951
NZ_CP047147.1|WP_159312682.1|3739177_3740080_+|phosphoribosylaminoimidazolesuccinocarboxamide-synthase	unknown	unknown	gnl|CDD|237571
NZ_CP047147.1|WP_003949533.1|3745676_3746387_+|phosphoribosylformylglycinamidine-synthase-subunit-PurQ	unknown	unknown	gnl|CDD|235140

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP047147.1|WP_003949519.1|3729418_3729751_+|helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	4.6e-17	57.2	0.5

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_159312679.1|3722572_3723091_+|helix-turn-helix-domain-containing-protein	gnl|CDD|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	1.60071e-26
NZ_CP047147.1|WP_159313921.1|3727656_3729315_+|STAS-domain-containing-protein	gnl|CDD|223732	COG0659, SUL1, Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism].	1.67074e-117
NZ_CP047147.1|WP_003949534.1|3746383_3748633_+|phosphoribosylformylglycinamidine-synthase-subunit-PurL	gnl|CDD|234921	PRK01213, PRK01213, phosphoribosylformylglycinamidine synthase subunit PurL.	0
NZ_CP047147.1|WP_008413354.1|3727034_3727379_-|nuclear-transport-factor-2-family-protein	gnl|CDD|378915	pfam12680, SnoaL_2, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	2.30762e-08
NZ_CP047147.1|WP_003949519.1|3729418_3729751_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|197713	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor.	9.07104e-14
NZ_CP047147.1|WP_003949514.1|3723119_3723530_+|VOC-family-protein	gnl|CDD|319924	cd07263, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	8.59344e-39
NZ_CP047147.1|WP_078858062.1|3726113_3727022_+|Dyp-type-peroxidase	gnl|CDD|367887	pfam04261, Dyp_perox, Dyp-type peroxidase family. This family of dye-decolourising peroxidases lack a typical heme-binding region.	1.29902e-90
NZ_CP047147.1|WP_003949529.1|3742399_3743209_-|ABC-transporter-permease	gnl|CDD|223912	COG0842, COG0842, ABC-type multidrug transport system, permease component [Defense mechanisms].	9.65729e-11
NZ_CP047147.1|WP_018894829.1|3740292_3740958_-|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	5.82065e-60
NZ_CP047147.1|WP_037845302.1|3734087_3735863_+|hypothetical-protein	gnl|CDD|320687	cd07328, M48_Ste24p_like, M48 Ste24 endopeptidase-like, integral membrane metallopeptidase. This family contains peptidase M48-like proteins that are as yet uncharacterized, but probably function as intracellular, membrane-associated zinc metalloproteases; they all contain the HEXXH Zn-binding motif, which is critical for Ste24p activity. They likely remove the C-terminal three residues of farnesylated proteins proteolytically and are possibly associated with the endoplasmic reticulum and golgi.	1.80294e-06
NZ_CP047147.1|WP_008409762.1|3743205_3744189_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	6.84452e-97
NZ_CP047147.1|WP_159312680.1|3723583_3725974_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|223256	COG0178, UvrA, Excinuclease ATPase subunit [DNA replication, recombination, and repair].	0
NZ_CP047147.1|WP_003949522.1|3732377_3733652_+|phosphoribosylamine--glycine-ligase	gnl|CDD|234856	PRK00885, PRK00885, phosphoribosylamine--glycine ligase; Provisional.	0
NZ_CP047147.1|WP_003949531.1|3744725_3745043_-|Lsr2-family-protein	gnl|CDD|378714	pfam11774, Lsr2, Lsr2. Lsr2 is a small, basic DNA-bridging protein present in Mycobacterium and related actinomycetes. It is a functional homolog of the H-NS-like proteins. H-NS proteins play a role in nucleoid organisation and also function as a pleiotropic regulator of gene expression.	5.88457e-48
NZ_CP047147.1|WP_008409760.1|3745428_3745680_+|phosphoribosylformylglycinamidine-synthase-subunit-PurS	gnl|CDD|235659	PRK05974, PRK05974, phosphoribosylformylglycinamidine synthase subunit PurS; Reviewed.	2.46331e-40
NZ_CP047147.1|WP_159312681.1|3730211_3732317_+|DNA-polymerase-III-subunit-gamma-and-tau	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	0
NZ_CP047147.1|WP_129845642.1|3740967_3742323_-|histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	3.74645e-37
NZ_CP047147.1|WP_159312682.1|3739177_3740080_+|phosphoribosylaminoimidazolesuccinocarboxamide-synthase	gnl|CDD|237571	PRK13961, PRK13961, phosphoribosylaminoimidazole-succinocarboxamide synthase; Provisional.	0
NZ_CP047147.1|WP_003949533.1|3745676_3746387_+|phosphoribosylformylglycinamidine-synthase-subunit-PurQ	gnl|CDD|235140	PRK03619, PRK03619, phosphoribosylformylglycinamidine synthase subunit PurQ.	1.30918e-143

Protein sequences

>NZ_CP047147.1|WP_037845302.1|3734087_3735863_+|hypothetical-protein
MARAGAVAVLRVRGRAVALALLPAALAVVLLAGAPTGVLTGPVWDAARALVSAVAVLVLLAAAGLALAVARARPAVSPTVPVSEDSAPDLHRLVRDLADRLEVPAPSAIALTPDCDSWLEDRSHPALGADAVRPAHGQEPPAPVLVIGSPFLWWMRVAELRAVLAPVVAGTGPSAQPDIIAARRFVRGLDAAAALGTEPGRGPLARLVLGGTARLARLLLHACREEAAEMERAVAATSSERAKAVDYGLRIAAQEQVGLAYAGWDRLLNRVALPAWRIGRWPARLDAGVVAALTELSRRDRLADDFTTRLGERPACDLLEEPGTIDESTSLLAARLFHGEPAGSEPQWLPVDWEGYADEVVDRTWRTEAARLHRVLDGLGVPASEPGGATLARVLEHLAVPAGVPAAEPGGLPELTEAELATASDDELALRTGVDIGGEAAGRAATVPQPGGEVRRRVAERAEELAEALAAEVARDEARVPAGVPAPVGQGADETLSAGGRLPLCPLQPPRTGRELLAGHVAAMVCCSAMDTAGALPGLDWLDGPVLLVQGRRASDLAVRVTALVDQGDGGPLLTWVHQTGIRPDKPVRLV
>NZ_CP047147.1|WP_003949522.1|3732377_3733652_+|phosphoribosylamine--glycine-ligase
MKVLVIGSGAREHALCRSLSLDPDVTALYCAPGNAGIAEVAELHPVDALDGAAVARLATGLGADLVVVGPEAPLVAGVADAVRVAGIDCFGPSAEAARLEGSKAFAKDVMAGAGVPTARSYVCTTAAEIDTALDAFGAPYVVKDDGLAAGKGVVVTEDVDEAREHALNCVSAGGGRVVVEEFLDGPEVSLFAVTDGRTVVPLQPAQDFKRALDGDQGPNTGGMGAYSPLPWADPKLVDEVLETVLQPTVDELRRRGTPFSGLLYAGLAITSRGIRVIEFNARFGDPETQVVLARLRTPLAGVLRAAADGTLAALPPLRWSEEAAVTVVVASHNYPGTPRTGDPVEGLAEVAELDAPAAYVLHAGTRQDGDAVLSAGGRVLSVTATGADLTEARDRAYTAVARIRLDGSQHRSDIAARVAVEERG
>NZ_CP047147.1|WP_159312681.1|3730211_3732317_+|DNA-polymerase-III-subunit-gamma-and-tau
MSSLALYRRYRPESFAEVIGQEHVTDPLQQALRNNRVNHAYLFSGPRGCGKTTSARILARCLNCEQGPTPDPCGTCQSCQDLARNGPGSIDVIEIDAASHGGVDDARDLREKAFFGPASSRYKIYIIDEAHMVTSAGFNALLKVVEEPPEHLKFIFATTEPEKVIGTIRSRTHHYPFRLVPPGTLREYLAEVCGKEGSRVEDGVLPLVVRAGAGSVRDSMSVMDQLLAGAGEDGVTYAMATALLGYTDGSLLDSVVDAFAAGDGAAAFEVVDRVVEGGNDPRRFVADLLERLRDLVILAAVPDAAEKGLIDAPADLVERMQAQASVFGAAELSRAADLVNEGLTEMRGATSPRLQLELICARVLLPAAYDDERSTLARLERLERSGPPAQAAAPLAPQAYAPAQPQVPQAPPAAAPAPAPQQSAPPAPAPDAPPADAAPARPGAWPGSAAPGSGAPAPAARRPGGWPTAGAGGGPAPQQAEPQGPGRPQGQPQPQAAPATPPPGAVDARALWPNVLEAVKNRRRFTWILLSQNAHVAGFDGTTLQLGFLNAGARDNFASSGSEDVLKQALGEEFQVNWKIETVIDASGGQGPATPPGGGGGGGWGQAPAQPRPAAPAPAPAPAPPQPGPAAPPAPAPASQTPPAPQREQRPPAPEPPRRTTSIEDDIPEEDDPDLDESALSGHDLIMRELGATVVEEYTNE
>NZ_CP047147.1|WP_003949519.1|3729418_3729751_+|helix-turn-helix-transcriptional-regulator
MSTPLYQLKAEFFKTLGHPVRIRVLELLSRREHAVSELLSDIGVEPAHLSQQLAVLRRANLVVPRREGSAVHYSLTNPDVAELLRVARTILSGVLTDQAELLAGLRADES
>NZ_CP047147.1|WP_159313921.1|3727656_3729315_+|STAS-domain-containing-protein
MRSLLPTRADFAAMTRAPRRDLLAGLTVAIVALPLALGFGVSSGLGAEAGLATAVVAGALAALFGGSSLQVSGPTGAMTVVLVPIVAQYGPGGVLTVGLLAGVLLLALAVLKAGRYMRYVPAPVVEGFTLGIACVIGLQQVPNALGVTAPEGDSVLMVTWHAVEEFVRAPNWTATGLALGVAAVMLLGARWRPAVPFSIVAVVAATAAAQFFHLDGAAPIGALPSGLPAPSLDFLELSALGSLLAPALAVAALAALESLLSATVADGMTTGQKHDPDRELFGQGVANLAAPLFGGVPATAAIARTAVNVRSGAGSRLAALTHAAVLAVIVFAAAPLVSKIPLAALAGVLIATAVRMVEAGALRAMVRSTRSDAVVLVLTAVATLVLDLVLAVVIGLVVAGALALRAVALQARIDRTDAPSEPSAVHSDAEHAPPSEHIATYRVDGPLFFAGAHRVLLELSEVAGVRVVILRLARVTTMDATGALALKEAVEDLGRRGIAVLACGIRPAHRRTLASVGALEALRDREYATGSEALAAAHAHLGRTGPLPAGTA
>NZ_CP047147.1|WP_008413354.1|3727034_3727379_-|nuclear-transport-factor-2-family-protein
MASTEQVAERFHAALTAADADGLRGVLADEVTFEGPVATASGVAECVAGLVEMGKMISGDQVEVRLADGGNVLTWSTVRAGGGPGRPTVTWLRVDGERITAIRTVFDARGTGGR
>NZ_CP047147.1|WP_078858062.1|3726113_3727022_+|Dyp-type-peroxidase
MDAPLSAAAGFLVLVVKDGEEAAATVRSVVAGTDDLIKDITIRANGAMFTCNVGISHHGWPRLTGKPLPKELRPFREIKGEKHTAVATPGDLLYHLRAASPDLIVEFEKILLEAFGDSVTAVDDVTGFRYFDGRDLLEFADGTANPDGAALPAATLVGDEDPAYAGGSYVVVQKYLHDLSAWRAQTTGTQEEIIGRTKFDNVEKPDATEGQKSHKTLCTIQDADGEHDILRDNMPFAHPGTGEYGTYFIGYSRHLWVTEKMLERMFLGDPPPLHDRILDYSRAVTGVTFFCPARAFLAALGD
>NZ_CP047147.1|WP_159312680.1|3723583_3725974_+|ATP-binding-cassette-domain-containing-protein
MTRATRQDAPSAAPHAADHHDLIRVHGARENNLKDVSIEIPKRRLTVFTGVSGSGKSSLVFDTIAAESQRLINETYSAFLQGFMPTLARPEVDVLEGLTTAIIVDQQRLGADPRSTAGTATDANAMLRILFSRLGDPHIGSPNAYSFNVPSVRAHGAITVERGNAKTVRQSFTRTGGMCPHCEGRGTVSDIDLTQLYDDSKSISEGAFTIPGWKSDSWWTVRLYADSGFLDPDKPIRDFTEQEMRDFLYREPTKVKVEGTNLTYEGLIPKIQKSFLSKDREGMQPHIRAFVDRAVTFTACPECQGTRLSEAARSSRIGELNIADACALQITDLADWVATLDEPSVAPLLAALRHTLDSFVEIGLGYLSLDRPAGTLSGGEAQRVKMIRHLGSSLTDVTYVFDEPTIGLHPHDIERMNGLLLRLRDKGNTVLVVEHKPETIAIADHVVDLGPGAGTGGGTISFEGTVAGLRASDTLTGRHLDDRATLKKEVRKPTGTLEIRGADRHNLQDVDVDIPLGVLTVVTGVAGSGKSSLIHGSIPRSDEVVSVDQSPIRGSRRSNPATYTGLLDPIRKAFAKANGVKPALFSANSEGACPNCKGAGVVYTDLGMMAGVSATCEECDGKRFEASVLEHHLGGKDISEVLAMPVTEAEEFFREGEARTPAAHRVLTRLADVGLGYLTLGQPLTTLSGGERQRLKLATHMADKGGTYVLDEPTTGLHLADVDQLLALLDRLVDSGKSVIVIEHHQAVMAHADWIIDLGPGAGHDGGRVVFEGTPAELTENRGTVTGEHLAAYVGG
>NZ_CP047147.1|WP_003949514.1|3723119_3723530_+|VOC-family-protein
MHLTVHASFLPHNDPEAALAFYRDLLGLEVRDDVGYGGMRWITVGPPGGAGSAIVLLPPGADPGVTEDERRTIDAMMAKGTYGGILLATPDLTTTFEKLVAGDAEIVQEPTDQPYGVRDCAVRDPAGNLIRIQERR
>NZ_CP047147.1|WP_159312679.1|3722572_3723091_+|helix-turn-helix-domain-containing-protein
MSTSPPPAPHLGDLVLLRRVRDRIDREYARPLDVEALAQGVNMSAGHLSRQFRLAYGEPPYSYLMTRRIERAMALLRRGDLNVTEVCFAVGCSSLGTFSSRFTELVGVPPSVFRERQDLAGQNIEGMPACVAKQVTRPVRKARPPRGSALGGEPAGGAEPVRNREARTGRPA
>NZ_CP047147.1|WP_003949525.1|3737589_3739083_+|hypothetical-protein
MGSGHIRRWESGAYAHAVSDPFGQGPVPWLRGSENYFDDTGQVVPWYVEHAPAPGASGPRIPPPRPGGGPRTADDVDQQIKGFASAGAVAPGESIDFHITVNPPQQFSVDVYRIGHYGGDGASKITTSPRLSGIVQPPPLTADRTVSCHHWWLSWRLQVPTLWSIGAYVAVLTTADGRYRSHVPFTVRDSHPADLLLVLPDVTWQAYNLYPEDGRTGASLYHAWDESGKLLGEEDAAVTLSFDRPYAGAGLPLHVGHAYDFIRWAERYGYDLAYADTRDLHSGRIDPTRYRGLVFPGHDEYWSVPMRNTVELARDHGTSLVFLSANTMYWKVELSPSASGVPDRMLICRKRRGPGRPALWREVERAEQQLLGIQYAGRVPEPHPMVVRNASHWLWEATGAHEGDELPGMVAGEADRYFPRTRLPEHDSRILLAHSPYRDHEGVKRHQETSLYRAPSGALVFASGTFAWSPALDRPGHVDERVQRATANLLDRICKRD
>NZ_CP047147.1|WP_159312682.1|3739177_3740080_+|phosphoribosylaminoimidazolesuccinocarboxamide-synthase
MSGFVEKPEPVEVPGLVHLHTGKVRDLYQNEAGDLVMVASDRISAYDWVLPTEIPDKGRVLTQLSLWWFDQLADLVPNHVLSTTLPEGAPADWKGRTLVCKSLEMAPVECVARGYLTGSGLVEYEESRTVCGLALPPGLVNGSELPAAIFTPATKAAVGDHDENVSYEEVARLVGPETAAELRQTTLAVYSRALDVARERGLILADTKFEFGHDADGTLILADEVLTPDSSRYWPADTWEPGRAQPSFDKQFVRDWLTSEASGWDRHAEQPPPALPEEVVERTRAKYIEAYERLTGVSWG
>NZ_CP047147.1|WP_018894829.1|3740292_3740958_-|response-regulator-transcription-factor
MTEQSPEPPAPTGPAPSGGAPVRVLLADDEHLIRGAVAALLALEDDLVVVAEAATGPEALAMARAHRPDVAVLDLQMPGADGVAVATSLRDELPACRVMIVTGHGRPGNLKQALAAGVRGFVPKTVSAQRLAELVRSVHAGNRYIDPELAADAIAAGDSPLTAREAEVLELAADGAPVAEIAERAALSPGTVRNYLSSAVTKLGAENRHSAVRLARERGWV
>NZ_CP047147.1|WP_129845642.1|3740967_3742323_-|histidine-kinase
MTGTGDHEDAATYGATAQAAIRRPGRWWGRKGTAAKVESYTRISFHLFPVAQLVTALLSLTPVPARSALPVAGALLVHVVLGLRLTGQALDWVAGRRARPRRLLFAYMACGFAGAAIAALVLVKLPDDPPATYYTACVGTYVLFLAFSCGLGVLALRTHRQSLVAVAVATFGGWLLGSALLPAPAAAALALSTLLSAGGLTLASRFSIWLLQAVYELDEARHTRARLAVAEERLRFGRDLHDVLGRNLSVIALKSELAVQLARRERPEAVEQMAEVQRIAQESQREVREVVRGYREADLYTELLGARGVLSAAGITCTVTGTPTGLPRPVQAALAWVVREAVTNVLRHGNAAHCRIALTVVPAGPRAEGRPAVAELTVENDGVPSASDGSTGGHGLAGLRERLAAEQGTLEAGPAGKSAFRLVARVPVPADEVAESGVPGETAERARQELE
>NZ_CP047147.1|WP_003949529.1|3742399_3743209_-|ABC-transporter-permease
MSAVTTPPAPAGQEQRTRPLGRLAALARAELALLVRSKGVMFAALFVPFVLPFSVAQTVDDDTLKGTGLTLGLVLLPGAIGFSLLFAVYSSLVTIYATRRDELVLKRLRTGELRDNEILAGTAVPSIIIGLAQSAVLIVAVTALLDIGAPKAPHLAVLGILVGIVLMVVLAALTSALSRTAESAQVMAMPVLLVLMLGSGMVVPLEVFPDSLASVCERLPLTGAMALIRGGWTGELSGGDILTAAVTSLAWIALSLFAVRRWFRWEPRR
>NZ_CP047147.1|WP_008409762.1|3743205_3744189_-|ABC-transporter-ATP-binding-protein
MNTEDHVIDVTDLRRVYGGGFEAVRGVSFTVGRGELFALLGTNGAGKTSTLEVLEGLARPASGRVRVLGHDPFGERDAVRPRIGVMLQDGGFPSELTVRETLRMWAGCTSGARPIGEALEMVGLGKRADVRVKVLSGGEKRRLDLALALLGRPEVLFLDEPTTGLDAEGRQDTWSLVRELRAEGTTVLLTTHYLEEAEALADRLAILHEGRIASEGTVEDVVSAQPSRITFDLPDGWFPGDLPPLDQLGVTGHSHDGRTVRLMTQNLQQAATSLLLWARDAGVSLGSLDVRAASLEEAFLHIAREADGRGDSATAAASLDPRKETAA
>NZ_CP047147.1|WP_003949531.1|3744725_3745043_-|Lsr2-family-protein
MAQRVVVTLFDDIDGGEASETVAFGLDGTSYEIDLNRTNAEKLRETLEPYLRAGRKRSASGRAYQRTSVAADPAAVRAWARSHQMDVPPRGRIPKRVYEAFEQAN
>NZ_CP047147.1|WP_008409760.1|3745428_3745680_+|phosphoribosylformylglycinamidine-synthase-subunit-PurS
MARVVVDVMLKPEILDPQGQAVQRALPRLGFEGISDVRQGKRFELEVDGPVDDAALARIHELAETFLANTVIENFTVKVEEEK
>NZ_CP047147.1|WP_003949533.1|3745676_3746387_+|phosphoribosylformylglycinamidine-synthase-subunit-PurQ
MTAGPTPAARSNTRVGVVTFPGSLDDRDTQRAIRLAGAEAVPLWHKDKSLQQVDAVVLPGGFSYGDYLRAGAISRFSPLMEKVIDGARAGLPVLGICNGFQVLTEAHLLPGAMLGNDHLHFICRDQKLRVENTATAWTGDYVAGQEIHIPLKNMDGRYVADSRTLDMLEAEGRVAFRYLDVNPNGSLRDIAGITNEAGNVVGLMPHPEHAVEPLVGSGRTDGLPFFTSIIKKLVSA
>NZ_CP047147.1|WP_003949534.1|3746383_3748633_+|phosphoribosylformylglycinamidine-synthase-subunit-PurL
MSLDTVKHATDTPDTEQPWAELGLKEDEYARVREILGRRPTGAELAMYSVMWSEHCSYKSSKVHLRQFGEKAPQSDAMLVGIGENAGVVDVGQGYAVTFKVESHNHPSYVEPYQGAATGVGGIVRDIIAMGARPVAVVDPLRFGAADHPDTRRVLPGVVAGIGGYGNCLGLPNIGGEVVFDSCYQGNPLVNAGAIGVMRHEDIHLAKASGTGNKVILYGARTGGDGIGGASILASETFDDAKPSKRPAVQVGDPFQEKLLIECTLEAFAEKLVVGIQDLGAAGLSCATSELASNGSGGMRVTLDDVPLRDSTLSPEEILMSESQERMCAVVEPEKVDRFLAICEKWDVIATVIGEVTDGDRLEIFWHGEKIVDVDPRTVAHDGPVYERPLARPEWQDALQADDAGKLPRPATGGELKEQVLALLSSPNQASKSWITSQYDHFVQGNTVLAQPEDAGMIRVDEESGLGVAIATDGNGRFAKLDPYHGAQLALAEAYRNVATTGAKPLAVSDCLNFGSPEDPAVMWQFAEAIRGLADACQILGTPVTGGNVSLYNQTGDVAIHPTPVVAVLGVIDDVARRTPVAFAEEGQLLYLLGETREEFGGSAWSQVVHDHLGGLPPRVDLERERLLADILISASRDGMVDAAHDLSDGGLVQAVAESCLRGQKGARLVVPDGLDAFTFLFSESAGRVVVSVPRSEELRFTDMCGARGLPATRIGVVDGDALEVQGEFTLSLREVREAHEGTIEALMA

Crispr_ID: NZ_CP047147_20

• CRISPR_ID: NZ_CP047147_20
• CRISPR_location: 3766984-3767418
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 8 spacers

Consensus repeat of NZ_CP047147_20

Consensus_repeat	Method
GACCGTGGNGGTNNCCGT	CRT

spacers of NZ_CP047147_20

>20.1|3767002|24|NZ_CP047147|CRT
CGTGAGGGCGGTTTCCGTCGGGAC
>20.2|3767044|24|NZ_CP047147|CRT
CGTGAGGGCGGTTTCCGTCGCGAC
>20.3|3767086|48|NZ_CP047147|CRT
GGTGGCTTCCGTGGCGGTGACCGTCGTGAGGGTGGCTTCCGTCGGGAC
>20.4|3767152|36|NZ_CP047147|CRT
CGTGAGGGCGGTTTCCGTCGCGACGACCGCGGTGGT
>20.5|3767206|36|NZ_CP047147|CRT
GGCGGTGACCGTCGTGAGGGTGGCTTCCGTCGGGAC
>20.6|3767260|36|NZ_CP047147|CRT
CGTGAGGGCGGTTTCCGTCGCGACGACCGCGGTGGT
>20.7|3767314|45|NZ_CP047147|CRT
GGCGGCGACCGTCGTGAGGGTGGCTTCCGCCGCGACGACCGTGAC
>20.8|3767377|24|NZ_CP047147|CRT
CGTGACGACCGCCCCTCGGGCGGC

CRISPR arrays and Neighbor proteins around NZ_CP047147_20

CRISPR arrays

The CRISPR arrays of NZ_CP047147_20

>merge|NZ_CP047147|20|3766984-3767418|CRT
GACCGTGGCGGTGACCGTCGTGAGGGCGGTTTCCGTCGGGACGACCGTGGTGGTGACCGTCGTGAGGGCGGTTTCCGTCGCGACGACCGCGGTGGTGACCGTGGTGGCTTCCGTGGCGGTGACCGTCGTGAGGGTGGCTTCCGTCGGGACGACCGTGGTGGTGACCGTCGTGAGGGCGGTTTCCGTCGCGACGACCGCGGTGGTGACCGTGGCGGTTTCCGTGGCGGTGACCGTCGTGAGGGTGGCTTCCGTCGGGACGACCGTGGTGGTGACCGTCGTGAGGGCGGTTTCCGTCGCGACGACCGCGGTGGTGACCGTGGCGGTTTCCGTGGCGGCGACCGTCGTGAGGGTGGCTTCCGCCGCGACGACCGTGACGACCGTGGCGGCTTCCGCCGTGACGACCGCCCCTCGGGCGGCCACCGTGGCAGCGACCGT

>NZ_CP047147|20|1|3766984-3767418|CRT
GACCGTGGCGGTGACCGT	CGTGAGGGCGGTTTCCGTCGGGAC
GACCGTGGTGGTGACCGT	CGTGAGGGCGGTTTCCGTCGCGAC
GACCGCGGTGGTGACCGT	GGTGGCTTCCGTGGCGGTGACCGTCGTGAGGGTGGCTTCCGTCGGGAC
GACCGTGGTGGTGACCGT	CGTGAGGGCGGTTTCCGTCGCGACGACCGCGGTGGT
GACCGTGGCGGTTTCCGT	GGCGGTGACCGTCGTGAGGGTGGCTTCCGTCGGGAC
GACCGTGGTGGTGACCGT	CGTGAGGGCGGTTTCCGTCGCGACGACCGCGGTGGT
GACCGTGGCGGTTTCCGT	GGCGGCGACCGTCGTGAGGGTGGCTTCCGCCGCGACGACCGTGAC
GACCGTGGCGGCTTCCGC	CGTGACGACCGCCCCTCGGGCGGC
CACCGTGGCAGCGACCGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_159312698.1|3775634_3776492_-|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl|CDD|376556
NZ_CP047147.1|WP_003949541.1|3756257_3756464_+|developmental-transcriptional-regulator-BldC	unknown	unknown	gnl|CDD|133390
NZ_CP047147.1|WP_159313922.1|3774710_3774983_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159312697.1|3775404_3775632_-|holin	unknown	unknown	unknown
NZ_CP047147.1|WP_159312685.1|3754891_3755770_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_003949539.1|3753624_3754707_-|amino-acid-dehydrogenase	unknown	unknown	gnl|CDD|133444
NZ_CP047147.1|WP_008409756.1|3752798_3753050_-|DUF3073-domain-containing-protein	unknown	unknown	gnl|CDD|378620
NZ_CP047147.1|WP_159312694.1|3772997_3774218_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|238045
NZ_CP047147.1|WP_003949545.1|3763908_3764259_-|metallopeptidase-family-protein	unknown	unknown	gnl|CDD|240572
NZ_CP047147.1|WP_159312690.1|3767989_3771058_+|hypothetical-protein	unknown	unknown	gnl|CDD|379232
NZ_CP047147.1|WP_159312684.1|3753204_3753342_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_127454658.1|3764356_3765049_+|hypothetical-protein	unknown	unknown	gnl|CDD|237864
NZ_CP047147.1|WP_159312695.1|3774412_3774655_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159312688.1|3762227_3763805_-|hypothetical-protein	unknown	unknown	gnl|CDD|365906
NZ_CP047147.1|WP_159312686.1|3757041_3757320_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159312687.1|3757687_3761722_-|ATP-dependent-RNA-helicase-HrpA	unknown	unknown	gnl|CDD|182986
NZ_CP047147.1|WP_159312696.1|3774985_3775405_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159312692.1|3772285_3772480_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159312693.1|3772476_3772890_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159312691.1|3771548_3771794_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|238045

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_159312691.1|3771548_3771794_+|helix-turn-helix-domain-containing-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	2.81919e-14
NZ_CP047147.1|WP_159312688.1|3762227_3763805_-|hypothetical-protein	gnl|CDD|365906	pfam00149, Metallophos, Calcineurin-like phosphoesterase. This family includes a diverse range of phosphoesterases, including protein phosphoserine phosphatases, nucleotidases, sphingomyelin phosphodiesterases and 2'-3' cAMP phosphodiesterases as well as nucleases such as bacterial SbcD or yeast MRE11. The most conserved regions in this superfamily centre around the metal chelating residues.	5.7436e-15
NZ_CP047147.1|WP_003949541.1|3756257_3756464_+|developmental-transcriptional-regulator-BldC	gnl|CDD|133390	cd04762, HTH_MerR-trunc, Helix-Turn-Helix DNA binding domain of truncated MerR-like proteins. Proteins in this family mostly have a truncated helix-turn-helix (HTH) MerR-like domain. They lack a portion of the C-terminal region, called Wing 2 and the long dimerization helix that is typically present in MerR-like proteins. These truncated domains are found in response regulator receiver (REC) domain proteins (i.e., CheY), cytosine-C5 specific DNA methylases, IS607 transposase-like proteins, and RacA, a bacterial protein that anchors chromosomes to cell poles.	3.77068e-14
NZ_CP047147.1|WP_159312687.1|3757687_3761722_-|ATP-dependent-RNA-helicase-HrpA	gnl|CDD|182986	PRK11131, PRK11131, ATP-dependent RNA helicase HrpA; Provisional.	0
NZ_CP047147.1|WP_159312698.1|3775634_3776492_-|N-acetylmuramoyl-L-alanine-amidase	gnl|CDD|376556	pfam01510, Amidase_2, N-acetylmuramoyl-L-alanine amidase. This family includes zinc amidases that have N-acetylmuramoyl-L-alanine amidase activity EC:3.5.1.28. This enzyme domain cleaves the amide bond between N-acetylmuramoyl and L-amino acids in bacterial cell walls (preferentially: D-lactyl-L-Ala). The structure is known for the bacteriophage T7 structure and shows that two of the conserved histidines are zinc binding.	2.72253e-19
NZ_CP047147.1|WP_003949539.1|3753624_3754707_-|amino-acid-dehydrogenase	gnl|CDD|133444	cd01075, NAD_bind_Leu_Phe_Val_DH, NAD(P) binding domain of leucine dehydrogenase, phenylalanine dehydrogenase, and valine dehydrogenase. Amino acid dehydrogenase (DH) is a widely distributed family of enzymes that catalyzes the oxidative deamination of an amino acid to its keto acid and ammonia with concomitant reduction of NADP+. For example, leucine DH catalyzes the reversible oxidative deamination of L-leucine and several other straight or branched chain amino acids to the corresponding 2-oxoacid derivative. Amino acid DH -like NAD(P)-binding domains are members of the Rossmann fold superfamily and include glutamate, leucine, and phenylalanine DHs, methylene tetrahydrofolate DH, methylene-tetrahydromethanopterin DH, methylene-tetrahydropholate DH/cyclohydrolase, Shikimate DH-like proteins, malate oxidoreductases, and glutamyl tRNA reductase. Amino acid DHs catalyze the deamination of amino acids to keto acids with NAD(P)+ as a cofactor. The NAD(P)-binding Rossmann fold superfamily includes a wide variety of protein families including NAD(P)- binding domains of alcohol DHs, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate DH, lactate/malate DHs, formate/glycerate DHs, siroheme synthases, 6-phosphogluconate DH, amino acid DHs, repressor rex, NAD-binding potassium channel domain, CoA-binding, and ornithine cyclodeaminase-like domains. These domains have an alpha-beta-alpha configuration. NAD binding involves numerous hydrogen and van der Waals contacts.	1.6935e-86
NZ_CP047147.1|WP_008409756.1|3752798_3753050_-|DUF3073-domain-containing-protein	gnl|CDD|378620	pfam11273, DUF3073, Protein of unknown function (DUF3073). This family of proteins with unknown function appears to be restricted to Actinobacteria.	3.59284e-21
NZ_CP047147.1|WP_159312694.1|3772997_3774218_-|helix-turn-helix-domain-containing-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	5.23076e-10
NZ_CP047147.1|WP_003949545.1|3763908_3764259_-|metallopeptidase-family-protein	gnl|CDD|240572	cd12952, MMP_ACEL2062, Minimal MMP-like domain found in Acidothermus cellulolyticus hypothetical protein ACEL2062 and similar protein. The subfamily includes an uncharacterized protein from Acidothermus cellulolyticus (ACEL2062) and its homologs from bacteria. Although its biological role remains unclear, ACEL2062 contains a minimal metalloprotease (MMP)-like domain consisting of 3-stranded mixed 2-beta sheets and a HExxHxxGxxD/S (x could be any amino acid) motif. It may belong to a superfamily of bacterial zinc metallo-peptidases, which is characterized by a conserved HExxHxxGxxD motif.	4.35845e-49
NZ_CP047147.1|WP_159312690.1|3767989_3771058_+|hypothetical-protein	gnl|CDD|379232	pfam13517, VCBS, Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella. This domain of about 100 residues is found in multiple (up to 35) copies in long proteins from several species of Vibrio, Colwellia, Bradyrhizobium, and Shewanella (hence the name VCBS) and in smaller copy numbers in proteins from several other bacteria. The large protein size and repeat copy numbers, species distribution, and suggested activities of several member proteins suggests a role for this domain in adhesion (TIGR).	3.33803e-07
NZ_CP047147.1|WP_127454658.1|3764356_3765049_+|hypothetical-protein	gnl|CDD|237864	PRK14950, PRK14950, DNA polymerase III subunits gamma and tau; Provisional.	3.97565e-07

Protein sequences

>NZ_CP047147.1|WP_127454658.1|3764356_3765049_+|hypothetical-protein
MHQLSRPVRLLAVVAAVASASGCMSVGQEADDASPVSSTASPKDGKAAPDGGTEHGTGGSGFHGGHGAGREDGAERGDGDGREGRGDGRRVRGKDGRAVEPTDEPSGPTPSPRPPGAGDPGHGGPGGGTAPNPPKGPDPKPDPSTPPPQEPGPDPEPGPTTPPVEEPGEPGGGTPPQVPDDSGRGDGRPGPAGTPSMYRQAIESAPGVAREEEPGQESGGPEGPEGSGEG
>NZ_CP047147.1|WP_003949545.1|3763908_3764259_-|metallopeptidase-family-protein
MLEMTRDAFEELVSQALDQIPPELTRVMDNVAVFVEDEPDPSDPELLGLYEGTPLTERGEWYAGVLPDRISIYMGPTLRYCDTPEKVVDEVAVTVVHEIAHHFGIDDDRLHELGWG
>NZ_CP047147.1|WP_159312688.1|3762227_3763805_-|hypothetical-protein
MADATEESPRRTRAHRGQPAPKSPTGTAPLLTVRPEPGPLRRWAGLTAVVLLGAWLGLLAVGSVAAPVGPMDTRMTLRPSLTGGTKINVSPLGALELDSHVAPLRLDVDVDRLDPDRSAALVQNPALFSQLGDEVSADVQDGTLHLALRSVGAVVVGATALGLIVYRRPRRALAAGGLSLVLLASCGLAAYATWNPKSVLEPKFSGLLTSAPSVVGNARSIVSEFDVYQKELARLVTNMTKLYDATSTLPAYQPDPGTLRVLHVSDIHLNPAAWHIIESLVEQYEIDVIIDSGDTMDHGSAAENAFLDPVGRLEAPYVWVRGNHDSAATQRYLGKFKNVRVLDHGKAVDVGGLRIAGIGDPAYTPDRSQEAAGDPGEVAAGMKLAAELRRQAAAGTPVDIAVAHNPVAAKETDGEVPLVLAGHLHNRKTQLLPGGTRLRIEGSTGGSGLRAIEQDSPDPVMASVLYLDRDTRQLQAWDEISLGGLGLSTAEVSRHLPEENQPGAKPSPGGSESPSPGPSTPRPNQ
>NZ_CP047147.1|WP_159312687.1|3757687_3761722_-|ATP-dependent-RNA-helicase-HrpA
MSTISDLQPLLAELSLRDAHRLGRRLEGTRRIRKPESRAAVLEEIRAEAEKGAARMAERRARVPEIRYPEQLPVSQKKELIAEAIRDHQVVVVAGETGSGKTTQIPKICLELGRGVRGMIGHTQPRRIAARTVAERIADELDTPLGEAVGWKVRFTDQVRQDATFIKLMTDGILLAEIQTDRELRAYDTIIIDEAHERSLNIDFLLGYLAQLLPRRPDLKVVITSATIETDRFARHFGPRMATVGGKAADEEAAAPVIEVSGRTYPVEVRYRPLLEEGGEDADRDQVTAICEAVDELQAEGPGDVLVFLSGEREIRDTADALAKRNLRGTEILPLYARLSHQEQHRVFQRPGPGVRSRVVLATNVAETSLTVPGIKYVIDPGTARISRYSHRTKVQRLPIEPVSQASANQRKGRCGRTSDGVCIRLYSEEDFLARPEFTDAEILRTNLASVILQMTAAGLGDIEQFPFIDPPDHRNIRDGVQLLTELGALDPAEKDPRKRLTERGRRLAQLPVDPRLARMVLEADRNGCVREVMVIAAALSIQDPRERPSEKQAQADQQHARFRDETSDFLGFLNLWRYLRAQQKERSSSGFRRMCKAEYLNYLRIREWQDIYTQLRTVAKQMGLELREEDAADEPVHISLLSGLLSHIGMKDVKESATPAASAAKQGREGARGGRNEYLGARGAKFAVFPGSALFKKPPRFLMSAELVETSRLWARVNARIEPEWVEPLAGHLVKRTYSEPHWEKDQAAVVAYEKVTLYGVPIVAHRKVNYGRIDPEVSRDLFIRNALVEGDWRTHHQFFAANRKLLTEVEELEHRARRRDIMVDDETLFDFYDQRVPAEVVSGAHFDSWWKRKQKEEPELLDFERSMLLTEAAQAVTKADYPDSWRQGGLKFRVTYQFEPGADADGVTVHIPLQVLNQVTDEGFDWQIPGLREEVVTELIRSLPKPIRRHYVPAPNYAQAFLERAAPLQEPLPVTLARELQRIVGVPVTGDDFDTSRVPDHLKITFRIVDERRRTLAEDKDLEALKLKLRPKARQALSKAAAATAERSGGPSIERSGLTDWTIGALPEVFETRRAGQPVKAYPALVDEGPSVAVRLFDSPAEQRQAMRRGIRRLILLNIPVNPAKFAADRLTNQQKLNLSANPHGSVQALFEDCATAAADRLIADHGGPAWDEEAYRKLYEKVRADLVDTTLRAIQQVQQVLAAWGAVERRLKSTRSPALLANLADVRAQVSALIHPGFVTEAGLGRLGDLKRYLVAADRRLAQMPTGVQRDTTRMAKVKEMQDEYAWLLEQLPQGRPVPKEVLEIRWMIEELRVSYFAHALGTAYPVSDKRIVKAVDAAAP
>NZ_CP047147.1|WP_159312686.1|3757041_3757320_-|hypothetical-protein
MPESATAALPPAEDPDPPRADGAAREAAPGPLAGIQGPPAARPRHATRALLRAHLAAAVGTRHRTGRCAVCGRLRRLAEAGAAARDEGPATG
>NZ_CP047147.1|WP_003949541.1|3756257_3756464_+|developmental-transcriptional-regulator-BldC
MTARTPDAEPLLTPAEVATMFRVDPKTVTRWAKAGKLTSIRTLGGHRRYREAEVRALLAGIPQQRSEA
>NZ_CP047147.1|WP_159312685.1|3754891_3755770_+|hypothetical-protein
MPQVSAVRFPYASYLRVYEPLGAFPEPERGHWERYAHEAEPPAVEEELRARLTAVLATPPLPAPERESADAFVLWSGDTPLICPWTTRLRCWEALGETAELFPPTVLDAALPPAVRERAAADHARHLERHPDARAWIRQAAWSVPLSWFVLVGDEDREYDRGAEDEAPLLRYRTPMAQARRRVARGLRALRDSVAAADPSERGVRQAGGPLVTSLVDVGRWLEEFHPRALVELDYGGLVHVLPPELLDADRSAADVASGIRALGVGDDLVAGEAYARLVERWRAVRERQFAN
>NZ_CP047147.1|WP_003949539.1|3753624_3754707_-|amino-acid-dehydrogenase
MTDVSDGVLHTLFRSEQGGHEQVVLVQDRSSGLKAVIALHSTALGPALGGTRFYPYADEAEAVADALNLARGMSYKNALAGLDHGGGKAVIIGDPERDKTEELLLAYGRAVASLGGRYVTACDVGTYVADMDVVARENRWTTGRSPENGGAGDSSVLTAFGVYQGMRASAQHQWGDPSLRGRKVGVAGIGKVGRHLVGHLLAEGAEIVITDVREEAVRLITERHPEVTAVPDTEALIRTAGLDIYAPCALGGALNDASVPVLTAQVVCGAANNQLAHPGIEKDLADRGILYAPDYVVNAGGVIQVADELHGFDFDRCKQKAAKIFDTTLEIFARAKSDGVPPAAAADRLAEQRMAEGRRA
>NZ_CP047147.1|WP_159312684.1|3753204_3753342_+|hypothetical-protein
MVSTVEEPLSSLVSCEFNPPADGDPPTGVSLVSPWPGVPITLTGT
>NZ_CP047147.1|WP_008409756.1|3752798_3753050_-|DUF3073-domain-containing-protein
MGRGRAKAKQTKVARQLKYNSGGTDLSRLASELGASTSSQPPNGEPFEDDEDEDPYAQYADLYNDDEDEDDESGPASKQRRGA
>NZ_CP047147.1|WP_159312690.1|3767989_3771058_+|hypothetical-protein
MAQHARLRPTVAAVCALAVSAGLVSAVALPGTAAAAPAAAPAAAPAGAVIDAPSRFQPRVDEVFVAGEQGFLHREEGRAVEYTEYATGTTRKAENATWWNGTLGAWWSPAARTLELRPLEGEAPSVTIVLPKNQTWQRGHNASTVLTTSRETGGRTVMHLLRGAADGTVTDQEIPLGEGESFVNVLAQTHEAAVIGVRGADAVKRAFLLDYATGTTTPLFAGLASTPSRVTLTDRYVAGWDPSSPQVLTLDRRNLDAPVVRTVVPGPVKTTTRHQMALEIAGDQLLVVHQEAQPDHHVGQPLSAVRIGGGDPVTVLPHAQARLTPAPDGSVLVAGGASASDWAVHRIGAGADGRPTAAPVHALPPVAGTVRGLALAGGRLLTVGTDPVQGQPSLRSYELTTSGTPRVVSGPDTVTRSLGDYKACPDGGPSCASLTALGNGWAAHPSGNGVSVPLGQNASRVIGPMSWERPEIVAATGRHVLVKERGSAKYAVGDLEKFYDSNVIHTFTATAAALWGNKVWKPATAAGTVSAYDVKTKKTAAAVDTGSGCKPTALQAVGRWIYWACGGTKAGVFDQSLGKSVSVPAGGEPRLGDGFLVRATGEDLMVTDFSRGAGTKPATTLLASGVEPGHGIGWAVDPFGGNVAHVDADQRVHITDVPVPRSPVASIESRVEQNFVRAGGKEPWTGHWQLSHPADAWKVTFTDVTRKTVATVSGTARTAASISATWDGLATGGGKPQNGAHTWTVSVKAAGESSYVPVKAGTVQVSGGTAAYRDEQADGRGNVLTVNKNGTLTSHDFPATGVHDKWSRAGWHIKYTYVPFGDLTGDGCNDLLVRNTVGNLYRYDGVCGHPPAKTSTRTSLGGGWEAYNVLTSPGDLTGDGLPDLLARKSSTGDIWVFPGTKAGKLGAGKKIRSGWTYTHVVGAGDLNGDGHGDVLARAKDGTLYRYDGAGDGTLKSRVTVFTKWGSTYTHVLGVGDMTGDGKNDLLVVDNKGVVYRNTGNGKGSFSSRTKITTGWLTYKGIF
>NZ_CP047147.1|WP_159312691.1|3771548_3771794_+|helix-turn-helix-domain-containing-protein
MDRVPPLLPPDDLTARRQALGDQLRDARLAAGLTQEQLALATGIDRPSVVRIERGQQDAKLSTLLRLCNALGVRLVVVPPT
>NZ_CP047147.1|WP_159312692.1|3772285_3772480_-|hypothetical-protein
MTAGAVLPDPATLTDEQLRGSACVYGGSRLDPADAVSLGVQLDPRYPGARWYPRACPACAGARP
>NZ_CP047147.1|WP_159312693.1|3772476_3772890_-|hypothetical-protein
MSHPGALRWLITLDPSPDHALRWMLGTGRVLVPLGHAVSAVRTTGHQGLRAAARVPGPAVHHERSGHVFHLVPPDAEWTSAAGTLLGVDHWLALPAPEVLEPPGTYWLSPPDGTGTLTDLAALAEALTPQLPAEAVR
>NZ_CP047147.1|WP_159312694.1|3772997_3774218_-|helix-turn-helix-domain-containing-protein
MSMNVGREVREMRKTRRLTVRQLADRVAISVSLLEKIENGSRQASSGLIAALARALGVGPDRLTGQPYINGAEAEDRVQAVIPDLRRILLTYDNPDDLAVAPRPLPVLAAEMDTIAQMRQDGRYVELAPLLPGLLEELTHTALAGWGNSRVAYWWLARGYRAANSLSHKLGYHDLSLTAVERTHWAADKSGDPLMQVTAAYLRAGAMLRMGALASARRILEGLEQEVERLAPEAAMSGAQMAVQGAILLKLAVLEARAQRPEAAWQRLAEARAAAGFLGGDVDHYEMSFGPSNVRIHQVSMLIEHGDTEQALARLREWGTEQDAAEWELPADLAAERSSHHHIDVAVARLTEGDRDGALADLLAARASSPAHTRYHPTVRSTASTLVRLDRGQNDRLIQFARWVGI
>NZ_CP047147.1|WP_159312695.1|3774412_3774655_+|hypothetical-protein
MLVDLSFHHPDDPGQNFDADRELAAIPRVGEEVLWTDEVEHEGRPQARYRVYRVVDVCWSMGADTSGASVLVKMEFRSQD
>NZ_CP047147.1|WP_159313922.1|3774710_3774983_-|hypothetical-protein
MDLAAIAPAGVALLVGVLSWTQARATNRRSDFTTITDQLRQDLREERTQRKLLTSYVLEFWRWGARVGPDTPAGPPPDPPPDLDLTPWRQ
>NZ_CP047147.1|WP_159312696.1|3774985_3775405_-|hypothetical-protein
MRAPVLAFSHRRAFLATIGAAWAGYGVGIILDPRYGTARGLAHITRHVPLDALGWMWVGCGLVALVAALLGRCPRVQAAGFAAVAAPATLWGTAFTITWATGDYPSAIGSVCGWLGFALGILWVSGMDDPLPRHLRKKR
>NZ_CP047147.1|WP_159312697.1|3775404_3775632_-|holin
MAASSAPIETKVKASSVATYLLSLAALAILGAVTDDPSLIAGMPDALEPFVLALVPAAASAVAGWAAPHTPRPDA
>NZ_CP047147.1|WP_159312698.1|3775634_3776492_-|N-acetylmuramoyl-L-alanine-amidase
MAPPMSADRFIKALRDEGLSVVEVGSWRTHNRNSKGAWGPVNGVMIHHTVTSGSATSVRICRDGHSQLPGPLCHGVITKDGRVHLVGYGRTNHAGAGDGDVLAAVIAERALPKPNEANTDGNARFYGFECENLGDGKDPWPAAQLDAIERVSAAICRVHGWDAASVIGHLEWQPGKIDPRGFTMASMRTRVAKRLSVPAGKTPTPTTPDKEAPVNAKELHEAVWKRDAIPAPSTAKTAKTNPTWKAESFLPETYDQTNRILDVVRQLAKDVAALRAEVAALKKGA

Crispr_ID: NZ_CP047147_21

• CRISPR_ID: NZ_CP047147_21
• CRISPR_location: 3866269-3866603
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 5 spacers

Consensus repeat of NZ_CP047147_21

Consensus_repeat	Method
CCGGAACACCCCCGCCCTCGCGGGGACCAC	CRISPRCasFinder
CGGAACACCCCCGCCCTCGCGGGGACCAC	PILER-CR
CGGAACACCCCCGCCCTCGCGGGGACCAC	CRT

spacers of NZ_CP047147_21

>21.1|3866299|31|NZ_CP047147|CRISPRCasFinder
GGTCCAGAAGTCCTCGCCGAGGAACGTCCTC
>21.2|3866360|31|NZ_CP047147|CRISPRCasFinder
GCGTTCGGAGCGGACCCTCTGCCGAAGTACA
>21.3|3866421|31|NZ_CP047147|CRISPRCasFinder
ACGATGTCGCGGGTACGGGTCGCGTGCATCG
>21.4|3866482|31|NZ_CP047147|CRISPRCasFinder
CTGGCATTCTCGGCCTGCGCCAAAGAATTCT
>21.5|3866543|31|NZ_CP047147|CRISPRCasFinder
CTTGAACCCCCTCCCGCAAATCCGGTCCGCT
>21.6|3866299|32|NZ_CP047147|PILER-CR,CRT
GGTCCAGAAGTCCTCGCCGAGGAACGTCCTCC
>21.7|3866360|32|NZ_CP047147|PILER-CR,CRT
GCGTTCGGAGCGGACCCTCTGCCGAAGTACAC
>21.8|3866421|32|NZ_CP047147|PILER-CR,CRT
ACGATGTCGCGGGTACGGGTCGCGTGCATCGC
>21.9|3866482|32|NZ_CP047147|PILER-CR,CRT
CTGGCATTCTCGGCCTGCGCCAAAGAATTCTG
>21.10|3866543|32|NZ_CP047147|PILER-CR,CRT
CTTGAACCCCCTCCCGCAAATCCGGTCCGCTA

CRISPR arrays and Neighbor proteins around NZ_CP047147_21

CRISPR arrays

The CRISPR arrays of NZ_CP047147_21

>merge|NZ_CP047147|21|3866269-3866603|CRISPRCasFinder,PILER-CR,CRT
CCGGACCATCCCCGCCCTCGCGGGGACCACGGTCCAGAAGTCCTCGCCGAGGAACGTCCTCCAGGAATACCCCCGCCCTCGCGGGGACCACGCGTTCGGAGCGGACCCTCTGCCGAAGTACACCGGAACACCCCCGCCCTCGCGGGGACCACACGATGTCGCGGGTACGGGTCGCGTGCATCGCCGGAACACCCCCGCCCTCGCGGGGACCACCTGGCATTCTCGGCCTGCGCCAAAGAATTCTGCGGAACACCCCCGCCCTCGCGGGGACCACCTTGAACCCCCTCCCGCAAATCCGGTCCGCTACGGAACACCCCCGCCCTCGCGGGGGCCAC

>NZ_CP047147|21|17|3866269-3866603|CRISPRCasFinder
CCGGACCATCCCCGCCCTCGCGGGGACCAC	GGTCCAGAAGTCCTCGCCGAGGAACGTCCTC
CAGGAATACCCCCGCCCTCGCGGGGACCAC	GCGTTCGGAGCGGACCCTCTGCCGAAGTACA
CCGGAACACCCCCGCCCTCGCGGGGACCAC	ACGATGTCGCGGGTACGGGTCGCGTGCATCG
CCGGAACACCCCCGCCCTCGCGGGGACCAC	CTGGCATTCTCGGCCTGCGCCAAAGAATTCT
GCGGAACACCCCCGCCCTCGCGGGGACCAC	CTTGAACCCCCTCCCGCAAATCCGGTCCGCT
ACGGAACACCCCCGCCCTCGCGGGGGCCAC

>NZ_CP047147|21|5|3866270-3866603|PILER-CR
CGGACCATCCCCGCCCTCGCGGGGACCAC	GGTCCAGAAGTCCTCGCCGAGGAACGTCCTCC
AGGAATACCCCCGCCCTCGCGGGGACCAC	GCGTTCGGAGCGGACCCTCTGCCGAAGTACAC
CGGAACACCCCCGCCCTCGCGGGGACCAC	ACGATGTCGCGGGTACGGGTCGCGTGCATCGC
CGGAACACCCCCGCCCTCGCGGGGACCAC	CTGGCATTCTCGGCCTGCGCCAAAGAATTCTG
CGGAACACCCCCGCCCTCGCGGGGACCAC	CTTGAACCCCCTCCCGCAAATCCGGTCCGCTA
CGGAACACCCCCGCCCTCGCGGGGGCCAC

>NZ_CP047147|21|2|3866270-3866603|CRT
CGGACCATCCCCGCCCTCGCGGGGACCAC	GGTCCAGAAGTCCTCGCCGAGGAACGTCCTCC
AGGAATACCCCCGCCCTCGCGGGGACCAC	GCGTTCGGAGCGGACCCTCTGCCGAAGTACAC
CGGAACACCCCCGCCCTCGCGGGGACCAC	ACGATGTCGCGGGTACGGGTCGCGTGCATCGC
CGGAACACCCCCGCCCTCGCGGGGACCAC	CTGGCATTCTCGGCCTGCGCCAAAGAATTCTG
CGGAACACCCCCGCCCTCGCGGGGACCAC	CTTGAACCCCCTCCCGCAAATCCGGTCCGCTA
CGGAACACCCCCGCCCTCGCGGGGGCCAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_003949599.1|3873379_3873574_+|hypothetical-protein	unknown	unknown	gnl|CDD|373048
NZ_CP047147.1|WP_049979125.1|3871322_3872015_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_003949585.1|3861577_3861796_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_031178660.1|3869081_3869657_+|heme-binding-protein	unknown	unknown	gnl|CDD|377163
NZ_CP047147.1|WP_159313929.1|3861986_3862427_-|ATP-binding-protein	unknown	unknown	gnl|CDD|340413
NZ_CP047147.1|WP_159313930.1|3862780_3864049_+|XRE-family-transcriptional-regulator	unknown	unknown	unknown
NZ_CP047147.1|WP_159312753.1|3861792_3861990_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159312754.1|3865279_3865858_-|DUF4352-domain-containing-protein	unknown	unknown	gnl|CDD|378684
NZ_CP047147.1|WP_159312751.1|3859030_3860221_-|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|275041
NZ_CP047147.1|WP_159312756.1|3867410_3868694_-|sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
NZ_CP047147.1|WP_159312757.1|3873577_3874528_+|alpha-L-glutamate-ligase	unknown	unknown	gnl|CDD|275040
NZ_CP047147.1|WP_003949581.1|3858463_3859018_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_003949595.1|3870359_3870767_-|RidA-family-protein	unknown	unknown	gnl|CDD|223329
NZ_CP047147.1|WP_127450818.1|3861190_3861448_-|putative-ATP-grasp-modified-RiPP	unknown	unknown	gnl|CDD|275039
NZ_CP047147.1|WP_067413994.1|3872251_3873193_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|238045
NZ_CP047147.1|WP_159312752.1|3860217_3861183_-|ATP-grasp-ribosomal-peptide-maturase	unknown	unknown	gnl|CDD|275040
NZ_CP047147.1|WP_003949596.1|3870938_3871319_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|224647
NZ_CP047147.1|WP_159312755.1|3866742_3867402_-|response-regulator	unknown	unknown	gnl|CDD|225107
NZ_CP047147.1|WP_159312750.1|3856653_3858234_-|phosphate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270371
NZ_CP047147.1|WP_018893691.1|3869697_3870318_+|ankyrin-repeat-domain-containing-protein	unknown	unknown	gnl|CDD|223738

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_031178660.1|3869081_3869657_+|heme-binding-protein	gnl|CDD|377163	pfam03928, Haem_degrading, Haem-degrading. Haem_bdg is a bacterial protein that is up-regulated in response to haemin- and peroxide-based oxidative stress. It interacts with the SenS/SenR two-component signal transduction system. Iron binds to surface-exposed lysine residues of an octomeric assembly of the protein.	1.1607e-22
NZ_CP047147.1|WP_159313929.1|3861986_3862427_-|ATP-binding-protein	gnl|CDD|340413	cd16936, HATPase_RsbW-like, Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains. This family includes histidine kinase-like ATPase (HATPase) domain of RsbW, an anti sigma-B factor as well as a serine-protein kinase involved in regulating sigma-B during stress in Bacilli. The alternative sigma factor sigma-B is an important regulator of the general stress response of Bacillus cereus and B. subtilis. RsbW is an anti-sigma factor while RsbV is an anti-sigma factor antagonist (anti-anti-sigma factor). RsbW can also act as a kinase on RsbV. In a partner-switching mechanism, RsbW, RsbV, and sigma-B participate as follows: in non-stressed cells, sigma-B is present in an inactive form complexed with RsbW; in this form, sigma-B is unable to bind to RNA polymerase. Under stress, RsbV binds to RsbW, forming an RsbV-RsbW complex, and sigma-B is released to bind to RNA polymerase. RsbW may then act as a kinase on RsbV, phosphorylating a serine residue; RsbW is then released to bind to sigma-B, hence blocking its ability to bind RNA polymerase. A phosphatase then dephosphorylates RsbV so that it can again form a complex with RsbW, leading to the release of sigma-B.	1.10893e-15
NZ_CP047147.1|WP_067413994.1|3872251_3873193_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.68122e-08
NZ_CP047147.1|WP_159312751.1|3859030_3860221_-|methyltransferase-domain-containing-protein	gnl|CDD|275041	TIGR04188, conserved_hypothetical_protein, methyltransferase, ATP-grasp peptide maturase system. Members of this protein family are predicted SAM-dependent methyltransferases that regularly occur in the context of a putative peptide modification ATP-grasp enzyme (TIGR04187, related to enzymes of microviridin maturation) and a putative ribosomal peptide modification target (TIGR04186).	2.99673e-170
NZ_CP047147.1|WP_159312754.1|3865279_3865858_-|DUF4352-domain-containing-protein	gnl|CDD|378684	pfam11611, DUF4352, Domain of unknown function (DUF4352). Members of these family are putative lipoproteins that fall into the Antigen MPT63/MPB63 (immunoprotective extracellular protein) superfamily.	1.34227e-09
NZ_CP047147.1|WP_018893691.1|3869697_3870318_+|ankyrin-repeat-domain-containing-protein	gnl|CDD|223738	COG0666, Arp, FOG: Ankyrin repeat [General function prediction only].	7.2411e-14
NZ_CP047147.1|WP_159312756.1|3867410_3868694_-|sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	2.36333e-51
NZ_CP047147.1|WP_159312757.1|3873577_3874528_+|alpha-L-glutamate-ligase	gnl|CDD|275040	TIGR04187, conserved_hypothetical_protein, ATP-grasp ribosomal peptide maturase, SAV_5884 family. Members of this protein family are ATP-grasp ligase family enzymes that regularly occur in a contexts with a methyltransferase and a putative ribosomally translated post-translationally modified peptide precursor. Because of this conserved gene neighborhood and close sequence similarity to ATP-grasp enzymes from microviridin/marinostatin biosynthesis cassettes, this enzyme is suggested also to serve as a peptide maturase.	2.44073e-98
NZ_CP047147.1|WP_003949595.1|3870359_3870767_-|RidA-family-protein	gnl|CDD|223329	COG0251, TdcF, Putative translation initiation inhibitor, yjgF family [Translation, ribosomal structure and biogenesis].	3.61696e-22
NZ_CP047147.1|WP_127450818.1|3861190_3861448_-|putative-ATP-grasp-modified-RiPP	gnl|CDD|275039	TIGR04186, conserved_hypothetical_protein, putative ATP-grasp target RiPP. A RiPP is a ribosomally produced, post-translationally modified peptide. This family regularly occurs next to ATP-grasp enzymes related to those of microviridin maturation and next to a methyltransferase.	3.30419e-20
NZ_CP047147.1|WP_003949599.1|3873379_3873574_+|hypothetical-protein	gnl|CDD|373048	pfam14404, Strep_pep, Ribosomally synthesized peptide in Streptomyces species. A ribosomally synthesized peptide related to microviridin and marinostatin, usually in the gene neighborhood of one or more RimK-like ATP-grasp. The gene-context suggests that it is further modified by the ATP-grasp. The peptide is predicted to function in a defensive or developmental role, or as an antibiotic.	1.56854e-25
NZ_CP047147.1|WP_159312752.1|3860217_3861183_-|ATP-grasp-ribosomal-peptide-maturase	gnl|CDD|275040	TIGR04187, conserved_hypothetical_protein, ATP-grasp ribosomal peptide maturase, SAV_5884 family. Members of this protein family are ATP-grasp ligase family enzymes that regularly occur in a contexts with a methyltransferase and a putative ribosomally translated post-translationally modified peptide precursor. Because of this conserved gene neighborhood and close sequence similarity to ATP-grasp enzymes from microviridin/marinostatin biosynthesis cassettes, this enzyme is suggested also to serve as a peptide maturase.	5.29642e-134
NZ_CP047147.1|WP_003949596.1|3870938_3871319_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	6.12361e-31
NZ_CP047147.1|WP_159312755.1|3866742_3867402_-|response-regulator	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.14034e-68
NZ_CP047147.1|WP_159312750.1|3856653_3858234_-|phosphate-ABC-transporter-substrate-binding-protein	gnl|CDD|270371	cd13653, PBP2_phosphate_like_1, Substrate binding domain of putative ABC-type phosphate transporter, a member of the type 2 periplasmic binding fold superfamily. This subfamily contains uncharacterized phosphate binding domains found in PstS proteins that serve as initial receptors in the ABC transport of phosphate in eubacteria and archaea. After binding the ligand, PstS interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The PstS proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	4.42917e-41

Protein sequences

>NZ_CP047147.1|WP_159312754.1|3865279_3865858_-|DUF4352-domain-containing-protein
MRRQLAIAAASFTAVLGLAACDTEVTSSPDKPAAADDAKPGKEADKAEQAEDKETVAKVGDAITLKGFDGEKVEVTVVKVVDPAKSKDEFMAPEDGNRWLGIQFQLVNKGDKAYQDSPTNGMQVADAEGQMFQTAFGEITAGPALSSDVRLAPGAKALGWVTFDVPKDVKVSQVQVALNSGMADHTGQWTLR
>NZ_CP047147.1|WP_159313930.1|3862780_3864049_+|XRE-family-transcriptional-regulator
MRNLALEAWMREHGYSANALAEAVNQAVDRLRGRPGSHDGASVRAWKSGRIRWPHAVTRLALEEVTGLPITDLGFVPRGRVAPAPAASEQEESDMKRRTLVGGIAAVAAAAAPGSSTRRIGMGDVHRLQHRFAEIIASDHRHGGQLGIEQKAAALADEALNLQNSGSASQRVRASLYASAAAFRSSAMWAAIDGGRYDIAKAHMREAQALAEMSGDQAIKFRIWSHTGTMYRHLGRPADALAANDVARSLHITRRDPLFACLGHARHAATLGLTGDDRGVKRLLGCARDSFESAEPDVVRPVWMTPVRDGAELETLSLAAHLRLGNYPQAEAHAHRSLTLLAPQMLRDRAINTARLAQAQLGQGAEEAAVTTAKQIPVDAAVRHARVSQMLRQFTTVLRTLAPDSRAFHSWDEHLAACGTAV
>NZ_CP047147.1|WP_159313929.1|3861986_3862427_-|ATP-binding-protein
MAGTSNAPHPTQPHLEPAPTGHPAYTETLPCTPESALAARRLIRQALGAWALDDLADDACLVAVEMVANACRHTRSPVIRVSVTRLDGTTVEIAVTDRSRVLPARKPAAPDALDGRGLLLVDAIAARWGADPQRWGKRVWAEVRAA
>NZ_CP047147.1|WP_159312753.1|3861792_3861990_-|hypothetical-protein
MNAYERPDTYERRGAPGCRQCEELRDEEAQARREFDHSRAVDCRVLLRRHPHHDSPAPPAPTAPR
>NZ_CP047147.1|WP_003949585.1|3861577_3861796_-|hypothetical-protein
MTEPPARLPHPRRHWTPGTCWRCEAREVPVLWLGPVQTSSGTGSFTACDPCVRRLETYVRRELALRDTAPAF
>NZ_CP047147.1|WP_127450818.1|3861190_3861448_-|putative-ATP-grasp-modified-RiPP
MPITSPRTARPWGAARLAPYPTTTHVPYCRTEIDPLTQLGVALDRHGRVVEMGKHGTSTGTETNTTTSSDGQNNDQGHDQDSDKD
>NZ_CP047147.1|WP_159312752.1|3860217_3861183_-|ATP-grasp-ribosomal-peptide-maturase
MTEQGPVLVATETDDATADMVIGELNRRSVPVVRFNPADLQDGTLTVSARFGTCPGVPVAGQVRTPSRTADLTRVRAVYWRRPDWPAYARLGADDARYAAAQARHGLGGTLYSLAGPRWVNHPLRNAAADHKPAQLALAQRLGLPVPATLITNDPDEARDFLHTHGQVIHKPLRWTPYQRDGVPVTGWAAPVTADEIDEGVRVTPHLFQARVPKVADLRVLVVGRRLFAVRIDSGLLDWRRDYSALTYSVATLPAPVSAALLAFLDHCHLPTGSFDLALDRAGTPWFLELNPNGQWAWLEHATGLPMAATLADLLAEGATP
>NZ_CP047147.1|WP_159312751.1|3859030_3860221_-|methyltransferase-domain-containing-protein
MTDPTTTERHALAARLARSGALHTPTWRRAVESVPREPFLHPGVFLPEPRGRWRPFLADRSPEAEWTRLAYSDQSLVTQLDGSLTPDQATTPEPVPGVPTSSSTEPALVLRMLESLEVEEGQEVLEIGTGTGYSTALLCHRLGEDNVTTVDVDPGVARRADDALESIGVSTWTVTGDGLLGHPPRSPYDRVIATCAVRRVPYTWVRQTRPGGVILTTLGSWPHGGGLAKVTVGADGTAEGRIVGPVSFMQARAQAQPPVTGDLAARAAYADCEREVRVPPTVLEEWTPAFLAQLTVPDAQLVHARTAEGEQRTYLFDPGRESFAEFAPGPRNAAGWTVRQGGPVALWDQVEETLLAWRDAGSPGVDAVRLRVTETAHHYWLDGTSAPSLRWEHALR
>NZ_CP047147.1|WP_003949581.1|3858463_3859018_+|hypothetical-protein
MTMTDPYTCPSCSCGQNARTVAVGPPQLEEERPETARERVNRKWNEVLQETRVAQTGISILFGFLLSVAFTSLFGELAGLDRGIYVVTVVLAALATASLIAPVSLHRFLSGLRVKDELVDAAARLMVCGMVLLALTICGTLLLILRTAVPSLLAEVLVGGVMVWFGLCWYVLPWMIRRRAGRRR
>NZ_CP047147.1|WP_159312750.1|3856653_3858234_-|phosphate-ABC-transporter-substrate-binding-protein
MEWVNAENVIAVGTFAVASSIAFGQWWYERMVPRRRRIGYRVQLDTAIGDDDGTGGGNTRLGLFDEADGMDEASVVLLRIENDGALSVSIGDYTSGGLHGMTATFDGREVHGVAVTVGPGSGALMSHFTPAHGLEYSGSSLRIPRVPLNKGEYFKLLVLLSGGTVGSKVTVSGGVQDGDVHPNESLTPDEKPPVFSRPARLTSMAFLVGIALLAGLIVTGGERPPPMGCATGSLEVTGSTAFAPVAEELAEAYMEQCPGSRITVAAHGSTTGLRELAERGAAAKDGAPALVALSDGPAPEGQETGDAGNEGGEAGEGGSLAGTRLAVSVFTLLAHADVPVRNLTLADLRRIYAGEVTDWREVGADRSLPIVLVGRGAASGTRDVLQRRLLEGAFEPPASSRDCSRKDNPKASVIRCELDTTDQVIATVARVPGALGYSELRTTSTLEGVRRISLDGRRPSLDGAGHDAYPYREIEYAYTYGRPPADSLAAGFLAFTTRGPGQDVVRTHGHLPCGTPEGLRVCGAAD
>NZ_CP047147.1|WP_159312755.1|3866742_3867402_-|response-regulator
MPAADVEPPTPAPVRLLLCDDHAVVRAGLRALLSSAPGIEVVAEAGSGEEALALTTLHHPDLVLMDLQLGEGIDGVETTRRLTTLPDHPPYVLVLTTYDTDADITRAVEAGATGYLLKAERPEELFTAIRAAASGRTALSPPVAQRVMTHLRNPQPELTPRERDILRHLTQGLGNREIARALFISEATVKTHLGRIYQKLGVETRAGAVAVGKERRLLG
>NZ_CP047147.1|WP_159312756.1|3867410_3868694_-|sensor-histidine-kinase
MRHPDDHPQPPSTSPGPPASPASGAFAPGAQTRDDRLLSALLTTAFVVLLAGALLRYVLKHGDSDRLPWILGLSVVLAVVQVAGQARPGSRRAGRVRLAVVVACWVVVVLLAPSFAWCAVPLIHTALRLLPTRSAVALVTALATLVVLAELRLADGFDPNHLLLPPVVAALATGVFVYLTREATRRQHLIDDLVRTRRELAATERREGTLAERQRLSREIHDSLAQGLSSQNMLLQAADRQWDTDPQAARTHLRTAASIAAHGLTEARRLVHDLAPADLAEGAGLAQALATLAARESRDGLTVRFHAEGPDTHLPDQAASALLRTAQGALANIREHSGARTAALTLTCLDDTVALDVADDGRGFPAPEPGGTRDPLGDPDPLRGHGLPAIRARLRQLGGTLAIESTPGEGAVLTATIPLTPATPPAP
>NZ_CP047147.1|WP_031178660.1|3869081_3869657_+|heme-binding-protein
MSFSTAFRSTRTRVLTGSAVVVALGAGVFGTVSASADTAPAAKPAAAQAAADASGRNVTQTSHLTIAAATKAAQAALDAAGKEKQKVSVAVVDRDGRALVTLRGDGAGPQSYEAAQEKAFTAVSWNAPTSELVKRLDSAPTLKDIPGTLFLAGGAPVTVKGAPVAGIGVAGAPSGDLDEKFAKAGVTALFR
>NZ_CP047147.1|WP_018893691.1|3869697_3870318_+|ankyrin-repeat-domain-containing-protein
MSRQEQKKAEARLIEAAGAGDAEGVKAALAAGARTEVSDASGRTPLLLASLGDHVAAARALVEAGADPDAQDDRDDSAWLVTGVTGSVEMMRTLLPAEPDQTLRNRFGGTALIPAAERGHVPYIRAALREASMEVDHVNGLGWTALLEAVILGDGGADHQETVRLLLAAGATPDLADRDGVTPREHAERRGFDRMAELLRKAEAAG
>NZ_CP047147.1|WP_003949595.1|3870359_3870767_-|RidA-family-protein
MAITLVDPEGLPKVGAYRQVAVATGSRLVFVAGQVAWDADGATVGAGDLAAQVERCYLNVHTALTAAGGTFADVAKLTVYVVDWTPDKMPHFLDGVARATARLGETPAAPGTLVGVAALDVPEHLVEVEATAVLD
>NZ_CP047147.1|WP_003949596.1|3870938_3871319_+|helix-turn-helix-transcriptional-regulator
MVTKQLSGTPEDADLSRADSLAREIFSEVANKWALLIIDALGESTVRFSEIRDRVEGISHKMLTQNLRMLERNGLVERYVHPTVPPRVDYTLTEPGLALRETTHLMCAWTQRYLGHIEGARGRFEG
>NZ_CP047147.1|WP_049979125.1|3871322_3872015_-|hypothetical-protein
MTEQRQQDNRPPTPSRRSQRRQTVAELRSQGRAGPGLRDILPGFLGMVLVTAGPVIGLAWLYRAYGLGALLLGALLLAAATLIGVPWRRAVVRRRGGRYTPAELAVLDDHGLAVAAERILRRDGWHVLPMPDDGRPRLYARDRRDRRLDVSFRPVEGGPDAAEPPGGPATLREPGGPADDRVIRVVISMGTYSPAEIEWASRPGGDHLVDGRQLQQWASGTSLDALGLLT
>NZ_CP047147.1|WP_067413994.1|3872251_3873193_-|helix-turn-helix-transcriptional-regulator
MPAPKSVDPTASLAALLGARIRRLRRAKGWSQTELAAKGATSQGRLAQMELGRETPSQTVCQLLDQALDADGELLALWAHIERTPYPDWSRAFMRFEQRATRMRKYMAATVPGLLQTESYVRALLAAARPSVGGALESLVRARLERRLLLTGDSPPYFWAILDESVLRRPIGQPEVMREQLTYLLHMQETERVSLQVLPFSAGVHPALGGSVTVLSFDRRPDVAYLESSHSGELIDDPEAAAGYGLAFDQLHAQALSPHASAAMIRNVLEGSYGVTRVSRRRRRSVAQEQLQQHAGWGLRRGPRRPARPGSDT
>NZ_CP047147.1|WP_003949599.1|3873379_3873574_+|hypothetical-protein
MTMTPFALQYARPQTGEPAAPYAFDQAEQVNVLAGGGYAAEDTALLARLGSTASTAGSKTHWDD
>NZ_CP047147.1|WP_159312757.1|3873577_3874528_+|alpha-L-glutamate-ligase
MTVLVLTCEEDVTADAVVLQLRRRGVPVLRLDPAEFPGRVDLAVRVTPDGQVTGHLAAPGGRVALEEIRSVWVRRPGTPGAHVSAEQRAWITLECERALWGALRATGARWMNDPDALERSRHKLWQLATAARAGLRVPDTLVTTDPDEAARFQKTYADAGSGLVVKSVTGRHPQNPPLTLPTAAVPPDADFTGVAACATCLQQRVPKRTDLRLTVVGDRYFPAYVTPRTPTLDWRFLPADASTWVAGEVDGALRAAVRRYLQEAQLAYAAFDFAIDEQGDPWFLEANAGGQFLFAEIETGMPMTEAIAAWLAIRRE

Crispr_ID: NZ_CP047147_22

• CRISPR_ID: NZ_CP047147_22
• CRISPR_location: 4111137-4111394
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of NZ_CP047147_22

Consensus_repeat	Method
TGGCCTCAAGCGCCGGCCGGGCT	CRISPRCasFinder

spacers of NZ_CP047147_22

>22.1|4111160|29|NZ_CP047147|CRISPRCasFinder
CGGTGGCCTCAAGCGCCGGCCCGGCTCAG
>22.2|4111212|41|NZ_CP047147|CRISPRCasFinder
GTCATTGGCCGGGCTCCGTATCGACCGTGGCGGTCACTGAT
>22.3|4111276|38|NZ_CP047147|CRISPRCasFinder
TCGACCGGCGGCCCCGGACGCCTGCCGGGGCCGGGAGG
>22.4|4111337|35|NZ_CP047147|CRISPRCasFinder
TGAACAGGCGGCCCTGCACCCCCGCCGGAGCCGGA

CRISPR arrays and Neighbor proteins around NZ_CP047147_22

CRISPR arrays

The CRISPR arrays of NZ_CP047147_22

>merge|NZ_CP047147|22|4111137-4111394|CRISPRCasFinder
CGGCCTCAAGCGCCGGCCGGGCTCGGTGGCCTCAAGCGCCGGCCCGGCTCAGTGGCCTCAAGCGCCGGCCGGGCTGTCATTGGCCGGGCTCCGTATCGACCGTGGCGGTCACTGATTGGCCTCAAACGCCGGCCGGGCTTCGACCGGCGGCCCCGGACGCCTGCCGGGGCCGGGAGGCGGCCTTAAGCGCGGGCCGGGCTTGAACAGGCGGCCCTGCACCCCCGCCGGAGCCGGAGGCGGCCAAGCGTCGGCCGGGCG

>NZ_CP047147|22|18|4111137-4111394|CRISPRCasFinder
CGGCCTCAAGCGCCGGCCGGGCT	CGGTGGCCTCAAGCGCCGGCCCGGCTCAG
TGGCCTCAAGCGCCGGCCGGGCT	GTCATTGGCCGGGCTCCGTATCGACCGTGGCGGTCACTGAT
TGGCCTCAAACGCCGGCCGGGCT	TCGACCGGCGGCCCCGGACGCCTGCCGGGGCCGGGAGG
CGGCCTTAAGCGCGGGCCGGGCT	TGAACAGGCGGCCCTGCACCCCCGCCGGAGCCGGA
GGCGGCCAAGCGTCGGCCGGGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_030307727.1|4105298_4105649_+|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132914
NZ_CP047147.1|WP_003949863.1|4116027_4116948_-|diiron-oxygenase	unknown	unknown	gnl|CDD|378680
NZ_CP047147.1|WP_159312835.1|4118742_4119378_-|response-regulator	unknown	unknown	gnl|CDD|225107
NZ_CP047147.1|WP_159312833.1|4117123_4117762_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_003949866.1|4118353_4118731_+|fluoride-efflux-transporter-CrcB	unknown	unknown	gnl|CDD|223317
NZ_CP047147.1|WP_103505665.1|4104395_4104779_+|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132914
NZ_CP047147.1|WP_003949857.1|4109583_4109895_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_129845289.1|4114172_4115885_-|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|215457
NZ_CP047147.1|WP_159312830.1|4109991_4110954_-|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|223566
NZ_CP047147.1|WP_159312831.1|4111498_4112284_+|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl|CDD|238870
NZ_CP047147.1|WP_159312832.1|4112688_4113957_-|tRNA-4-thiouridine(8)-synthase-ThiI	unknown	unknown	gnl|CDD|234960
NZ_CP047147.1|WP_159312836.1|4120898_4121807_+|zinc-binding-dehydrogenase	unknown	unknown	gnl|CDD|176231
NZ_CP047147.1|WP_003949856.1|4107891_4109403_+|DEAD/DEAH-box-helicase	unknown	unknown	gnl|CDD|223587
NZ_CP047147.1|WP_003949850.1|4103287_4104349_+|cobalamin-binding-protein	unknown	unknown	gnl|CDD|227345
NZ_CP047147.1|WP_129828322.1|4119374_4120649_-|sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
NZ_CP047147.1|WP_030307725.1|4106343_4106688_-|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|133394
NZ_CP047147.1|WP_159312829.1|4105776_4106316_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|340413
NZ_CP047147.1|WP_003949855.1|4107273_4107477_+|cold-shock-protein	unknown	unknown	gnl|CDD|224197
NZ_CP047147.1|WP_159312834.1|4117805_4118357_+|camphor-resistance-protein-CrcB	unknown	unknown	gnl|CDD|376809
NZ_CP047147.1|WP_159312828.1|4101602_4103291_+|SpoIIE-family-protein-phosphatase	unknown	unknown	gnl|CDD|369272

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_030307727.1|4105298_4105649_+|STAS-domain-containing-protein	gnl|CDD|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	2.45894e-20
NZ_CP047147.1|WP_003949863.1|4116027_4116948_-|diiron-oxygenase	gnl|CDD|378680	pfam11583, AurF, P-aminobenzoate N-oxygenase AurF. This family is a metalloenzyme which is involved in the biosynthesis of antibiotic aureothin by catalyzing the formation of p-nitrobenzoic acid from p-aminobenzoic acid. AurF is a non-heme di-iron monooxygenase which creates nitroarenes via the sequential oxidation of aminoarenes.	5.73174e-103
NZ_CP047147.1|WP_159312835.1|4118742_4119378_-|response-regulator	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.12262e-67
NZ_CP047147.1|WP_003949866.1|4118353_4118731_+|fluoride-efflux-transporter-CrcB	gnl|CDD|223317	COG0239, CrcB, Integral membrane protein possibly involved in chromosome condensation [Cell division and chromosome partitioning].	6.43239e-31
NZ_CP047147.1|WP_103505665.1|4104395_4104779_+|STAS-domain-containing-protein	gnl|CDD|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	5.6728e-15
NZ_CP047147.1|WP_159312830.1|4109991_4110954_-|FAD-dependent-oxidoreductase	gnl|CDD|223566	COG0492, TrxB, Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones].	1.64064e-41
NZ_CP047147.1|WP_129828322.1|4119374_4120649_-|sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	1.94461e-52
NZ_CP047147.1|WP_159312831.1|4111498_4112284_+|SGNH/GDSL-hydrolase-family-protein	gnl|CDD|238870	cd01832, SGNH_hydrolase_like_1, Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad from other serine hydrolases, but may lack the carboxlic acid. Myxobacterial members of this subfamily have been reported to be involved in adventurous gliding motility.	7.26057e-62
NZ_CP047147.1|WP_030307725.1|4106343_4106688_-|MerR-family-transcriptional-regulator	gnl|CDD|133394	cd04766, HTH_HspR, Helix-Turn-Helix DNA binding domain of the HspR transcription regulator. Helix-turn-helix (HTH) transcription regulator HspR, N-terminal domain. Heat shock protein regulators (HspR) have been shown to regulate expression of specific regulons in response to high temperature or high osmolarity in Streptomyces and Helicobacter, respectively. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their conserved N-terminal domains contain predicted winged HTH motifs that mediate DNA binding, while the dissimilar C-terminal domains bind specific coactivator molecules.	7.07293e-09
NZ_CP047147.1|WP_159312832.1|4112688_4113957_-|tRNA-4-thiouridine(8)-synthase-ThiI	gnl|CDD|234960	PRK01565, PRK01565, thiamine biosynthesis protein ThiI; Provisional.	5.39936e-166
NZ_CP047147.1|WP_159312836.1|4120898_4121807_+|zinc-binding-dehydrogenase	gnl|CDD|176231	cd08270, MDR4, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family. This group is a member of the medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, but lacks the zinc-binding sites of the zinc-dependent alcohol dehydrogenases. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P)-binding Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	3.51229e-103
NZ_CP047147.1|WP_003949856.1|4107891_4109403_+|DEAD/DEAH-box-helicase	gnl|CDD|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	1.35115e-118
NZ_CP047147.1|WP_003949850.1|4103287_4104349_+|cobalamin-binding-protein	gnl|CDD|227345	COG5012, COG5012, Predicted cobalamin binding protein [General function prediction only].	7.02863e-19
NZ_CP047147.1|WP_129845289.1|4114172_4115885_-|FAD-dependent-oxidoreductase	gnl|CDD|215457	PLN02852, PLN02852, ferredoxin-NADP+ reductase.	1.9226e-118
NZ_CP047147.1|WP_159312829.1|4105776_4106316_+|serine/threonine-protein-kinase	gnl|CDD|340413	cd16936, HATPase_RsbW-like, Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains. This family includes histidine kinase-like ATPase (HATPase) domain of RsbW, an anti sigma-B factor as well as a serine-protein kinase involved in regulating sigma-B during stress in Bacilli. The alternative sigma factor sigma-B is an important regulator of the general stress response of Bacillus cereus and B. subtilis. RsbW is an anti-sigma factor while RsbV is an anti-sigma factor antagonist (anti-anti-sigma factor). RsbW can also act as a kinase on RsbV. In a partner-switching mechanism, RsbW, RsbV, and sigma-B participate as follows: in non-stressed cells, sigma-B is present in an inactive form complexed with RsbW; in this form, sigma-B is unable to bind to RNA polymerase. Under stress, RsbV binds to RsbW, forming an RsbV-RsbW complex, and sigma-B is released to bind to RNA polymerase. RsbW may then act as a kinase on RsbV, phosphorylating a serine residue; RsbW is then released to bind to sigma-B, hence blocking its ability to bind RNA polymerase. A phosphatase then dephosphorylates RsbV so that it can again form a complex with RsbW, leading to the release of sigma-B.	4.38949e-15
NZ_CP047147.1|WP_003949855.1|4107273_4107477_+|cold-shock-protein	gnl|CDD|224197	COG1278, CspC, Cold shock proteins [Transcription].	3.10682e-34
NZ_CP047147.1|WP_159312834.1|4117805_4118357_+|camphor-resistance-protein-CrcB	gnl|CDD|376809	pfam02537, CRCB, CrcB-like protein, Camphor Resistance (CrcB). CRCB is a family of bacterial integral membrane proteins with four TMs.. Over expression in E. coli also leads to camphor resistance.	1.77245e-33
NZ_CP047147.1|WP_159312828.1|4101602_4103291_+|SpoIIE-family-protein-phosphatase	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	7.11996e-39

Protein sequences

>NZ_CP047147.1|WP_159312830.1|4109991_4110954_-|FAD-dependent-oxidoreductase
MPTPHTYDVVVIGGGAAGLAGAVTLGRARRTVLVVDAGTPRNAPAAGVHTFLSREGVSPAELLRTGRAEVTSYGGEIREGTVTDARREGDGFVVTLADGSEVRARRLLVTTGITDELPPVQGLAALWGKDVLHCPYCHGWEAQDLPTGVLATGPLSVHQALLWRQWTDDLTLFTHTTAGPTPEEREQLEARGTRIVDGEVTGVETDGEGRLAGVRLADGSTVPVRALATGGTLTARAGFLAGLGLETVPVEVGGTVIGSRLDTDATGLTSVPGVWAAGNVASPTDQVVISAGAAVRAAAVLNMDLVTEETRRAVEARRAG
>NZ_CP047147.1|WP_003949857.1|4109583_4109895_+|hypothetical-protein
MRCVIARFPFDLVKSEVVAKMKGVKPEPVTGEYVIIGRHHYPVKQVGEVITRQDRRDFSAGEVTRALTRLGFTCRPAPGTEPAVERTAVETAAAQLGGAPEQG
>NZ_CP047147.1|WP_003949856.1|4107891_4109403_+|DEAD/DEAH-box-helicase
MNQNRASRDDNRTGRRSGGGHRGAGAPRSAGPDRFRSPGRGGPQGARRSGGERTRAGARGEFAPPVTGTPALPPVDAFDQLGLPAPLLACLTAQGVTEPFPIQAATLPNSLAGRDILGRGRTGSGKTLAFGLALLARLEGRRAEPRSPLGLVLVPTRELAQQVTEALTPYARALRLRMTTVVGGLSLGRQASALRGGAEVVVATPGRLKDLIDRGDCRLDQVGATVLDEADQMADMGFMPQVTELLDQVRPGGQRLLFSATLDRNVDLLVRRYLDDPTVHSVDPSAGAVTTMEHHLFQVHGPDKHALATEIAARDGRVILFLDTKHAVDRLAEHLLRNGVRAAALHGGRSQAQRTRTLTQFRDGHVTALVATNVAARGIHVDDLDLVVNVDPPADHKDYLHRGGRTARAGASGSVVTLVLPEQRRSMSRLMADAGITPQTTRVRSGEAELSRITGARTPSGVPVVVRAPAPASPRRGASSSRGRRSPAAQARRAAAVRARPAA
>NZ_CP047147.1|WP_003949855.1|4107273_4107477_+|cold-shock-protein
MATGTVKWFNAEKGFGFIEQDGGGADVFAHYSNISAQGFRELIEGQKVSFDVTQGQKGPQAENIVVA
>NZ_CP047147.1|WP_030307725.1|4106343_4106688_-|MerR-family-transcriptional-regulator
MQVTRKTPPDPADKFDDEDYPAYTMGRAAEMIGATPAFLRAVGEARLITPLRSAGGHRRYSRYQLRVAARARELVDQGTPVEAACRIVILEDQLEEALRVNERLRDAASAAPRD
>NZ_CP047147.1|WP_159312829.1|4105776_4106316_+|serine/threonine-protein-kinase
MTVDEGDGDLIQYRQGAARAGNGRRPAQAPRIVEAPQHRQTRRAPQVPGTAGEARALVQQALRDSFGPDATGDTGDGLGDTVVVADALLVTSELVTNAIRHGGGLTGFDVQLEESHLTLHVSDASPELPAATRPDGPFDPDRPLVGGYGWPLVRRLCREVSVRPLPGGGKCVTVTLSLV
>NZ_CP047147.1|WP_030307727.1|4105298_4105649_+|STAS-domain-containing-protein
MLERSGMDITTSAELSAFVIGVHGDVDLHTAPALDAALAQALRAETSRTVVDLSGTGFADSSILGSLLRALRDHREQGRRLILAGPMSDLVTRLFEVTGTLAAFETAPDARAAREQ
>NZ_CP047147.1|WP_103505665.1|4104395_4104779_+|STAS-domain-containing-protein
MTPLNDPDDPDDLGGTGLTLTAEPAAPGTLALRLAGALDHESADALVREVARRLAERPAPRLLRLDCAGLTACDSLGLSALLMIGRRTGAAACALRLDRRPPHLDRLLEITGTHGYLVGPDEEPGPA
>NZ_CP047147.1|WP_003949850.1|4103287_4104349_+|cobalamin-binding-protein
MTTRTPEETVTAAEPLRALLWDALLAGDEYAAADVLFAALDDGLSAEEALLDVIGPVQAEVGLGWAANRLSVVQEHAATAMNDRIIAALAHRSPPPGEGRGRIAVACVEGEWHALPARLLAETLRLRGWRVDFLGAQAPTPHLIAHLHQTGPDLVALSSSIPTRLPTAHAAITACQAAGVPVLAGGAAFGADGRYARLLGADGWAPDARSAADVAAGGLGVPSGAVLHEPVDDLPHLADQEYTLVSRGRTRLVRETVDGLDDRFPAMRGYTERQRERTAEDIAHIVDFLATALYVDDDALFTSFLVWTAGILEARGVPARSLTPALELLGEPLRDFPRATRLLHRGGAALTGG
>NZ_CP047147.1|WP_159312828.1|4101602_4103291_+|SpoIIE-family-protein-phosphatase
MDVTKSSTIGAPRARTGRTAAPGAWDEAPCPVLVADAAGAVVTANAHATALFPAAVPGAPLSDAVPEWLGAAHRAAVAGQEPGDAVSGAVGERVYRAVARPAPGGGSRGAGAAGLVWWLSDDTGRAEAEAALAVERARTAFLSEASNALLATLNTERCMEVTAQLAARHLADGVVVVLPGAGRRTPLAWAVDGGGSTRALLALDPAEVPGLAEALQGFPPVPSRWIDPEALPTWAVPEEFDGPVGAVAVIPLPGHGVPAGALILLRREGKRGFTEPEEVFARLFAARAGAALSAARMYAEQAAVTQTLMRELLPPRLEQIRGVEFAGGYRASERGERVGGDFYDVHPTAGEAGASLVVLGDVCGKGLDAAVLTGKIRNTLQALLPMADDHPRVLRMLNDSLLSSHHTRFATLVLASAVREGDAVRLDLTSAGHPPPLLVRADGTVEAADTRGSLVGALPEVEATTARVTLRAGETCLLYTDGVTEARGGPFGDRMFGEERLREALAECAGMPAEAVVERVQMLAAQWVGAGEHDDMAMVAVTVPRKSPGGVVSAAGRGRGSA
>NZ_CP047147.1|WP_159312831.1|4111498_4112284_+|SGNH/GDSL-hydrolase-family-protein
MSVVRYVALGDSQTEGLGDGDEASGLRGWADRLAELLDAAEPGLRYANLAVRGQLAGQVRATQLDAALALRPDLATVVAGMNDLLRPRFDADTVGAELEAMFAALTGGGARVATLTFPAMERLVPLARPLAPRVPALNARIREAAARHGVLVVETYGEEVVVDPRLWSPDRLHAAPLGHARIAAAFAHALALPGSDRGWAVPLPAVPPVRGVRALAAEARWVSGFLGPWLGRRVRGRSSADGRVAKRPGLAPLGTAGRAGD
>NZ_CP047147.1|WP_159312832.1|4112688_4113957_-|tRNA-4-thiouridine(8)-synthase-ThiI
MNAVVPAQGVPDLAGPVPIGPCVLLKHGEVFLKGRNRHLFVERLHDNLRGALRGVTGSIWIKEMQNVTVLGGDAPQDELIARARRVMGFVAVQPAMRVETGEGAIVAAAVAALDGAAPGTTFAVRARRRHKPFPLTSTQLERLVGARIQEAHGLPVDLTRPDIRVEVEIDRKESYVSGLRHTGQGGLPVGTSGRALVLLSGGYDSPVAAHRAMRRGLRCDFVHFTGAPYTNAASAFKAYALARELNRYQPPGKLHIVALGHAQKQLAVAGAGRFQVVGQRRLMVKAASVLARRLRAQALVTGDALGQVASQTLSNMALVDEAATLPVLRPLIGWEKQEIIDEARRVGTAEISVLPDEDCCQLLAPRQVSLRTKLEDVAGFEKRLDADELIDQMLASAQVTRPGTDETPAPATPPAASACGTD
>NZ_CP047147.1|WP_129845289.1|4114172_4115885_-|FAD-dependent-oxidoreductase
MTYAITQTCCNDATCVAVCPVNCIHPTPEERAFGSTEMLHIDPRSCIDCGACADACPVDAIFPVDRLKPAHREYAALNAAYYEEEATTTEREEAAAAPAAVTGDGAEAQAEAAERTGPLFRAWDAPGFARSLPSDFAPLRVAVVGTGPAGMYAAEDLLLHTDAQVTLVDRLPVAGGLIRYGVAPDHPATKKVGEAFARFHHHPRVRMQLGLEVGKELSAAELAAHHDAVIYAVGAATDRRLGIPGEELPGSVSATGLVAWYNAHPDHAPDAVSLDAERVVVVGNGNVALDVARILVSDPDTLAATDIAGHALDALRGRRVREVVLLGRRGPEDAAYTRTELLALGHLDGVDLVVDDHDPRIGAAIDAAGPLDKAGMLGGVTRTAVDWSRPPEPGRRIVFRFHSAPLAVTGEQAVTGVQVTGGTAIPAQLVVRSIGHRGVAVPGLPFDETTGTVPHEGGRVRGRSNEYVVGWIKRGPSGGIGANRSCAAETVTTLLADAVAGGLPTPSGSAKEFARLARRRNRRLVDARGLAAIERAERESGRRDGRVRTKFATVPELVAAARRSRLRLPG
>NZ_CP047147.1|WP_003949863.1|4116027_4116948_-|diiron-oxygenase
MATTDAQPAAQDEGGHDINDITRRLLESSAKLSYDPATEVDWDTPLDKSFHGMSPEWSSLYGTRYWDELTEDQRKELTRQESGSVASTGIWFEVILQQMVLRDIYAKDPGSPEFQWALTEIADECRHSIMFARGVRKLGAPAYKPRRAVMELGRLFKTLAVGEAAYASILVAEEVLDVMQRDWMRDERVVPFVRTINNIHVVEESRHMKFARDETIKRLEKAGWLRRNVQALVISICAYFVITSMWNRDVYRNAGLNTERALAEAKANQHHKSMIRSSCSGLMDFLASAKLLTRPAAAVYRRANLL
>NZ_CP047147.1|WP_159312833.1|4117123_4117762_-|hypothetical-protein
MRPPAAPAPADPPGPGPEPEPGWNVALRRLLGDPYVFVATGPRRHEEWARDVLAVLRREVADPRGRLGLDADRTGPGRDAVPAYPFAPPPAERFPAYLRPLERAAAVGALAVMSEEWQFEPAPVRSRPDREAVLADARTLLDRYGPDAEYWTNAVAAGSGPAPDFVAAGLRGTASYTFLTGVYVNGLDLCDDLGLIAVSADEVGVFWSVGAS
>NZ_CP047147.1|WP_159312834.1|4117805_4118357_+|camphor-resistance-protein-CrcB
MSHPPHTPDGAAPDPAESHRANLPLPPPEPVDPDLGPEPAPGERPESQAPVLLAIALGGGLGAVIRYGATVLWPTPAGSFPWTILVVNVVGCAAMGVLMALLTEVWPDAPRLTRPFLGTGVLGGFTTFSTYAVDVQTLFDGGSPGRALGTLALTVAAALAAVAGASWLTRSAVRLGRAEGSLT
>NZ_CP047147.1|WP_003949866.1|4118353_4118731_+|fluoride-efflux-transporter-CrcB
MTWLLVVVGGMIGAPCRYLMDRAVQRRHSSGFPWGTLAVNMSGSLVLGVLVGARLTGAAPENLMVFAATGFCGAYTTYSTFSYETLRLAETGARGAAFANVALSVSAALGAAVMGLGVAKAVWGG
>NZ_CP047147.1|WP_159312835.1|4118742_4119378_-|response-regulator
MTVIRLLLADDHPIVRAGLRAVLETEPDFEIAGEAASAEEAVALAGRLAVDVVLMDLQFGPSARMNGSEATAAITARPGAPRVLVVTTYDSDADTLPAIEAGATGYLLKDAPPEELAEAVRTAAAGRTTLAPAVADRLLRRMRTPGTALSRRETEVLGLVAEGMSNLRISERLHLSQATVKSHLVHIYAKLGVDSRTAAVAAALERGLIRR
>NZ_CP047147.1|WP_129828322.1|4119374_4120649_-|sensor-histidine-kinase
MPSTAPAPAPPRAPLSTPAPRVLAWCLHLLVAALLVMAVGRALVDGGGQGWAVVVAGVAFGAVYAAGPVVPGVRGSRRGAVVWLVAVGVLWAGLLGLTADAMWLAFPLFFVQLHLLAGRAGPWAVALTTGVAVCSYAAHQGGFTAAAAIGPVIGAAVAVAVVRGYQALYRESEQRRRLIEELTRARADLAAAQHTAGVLAERERLAREIHDTLAQGLSSIQLLLRAAQRSLGGEEGAGRYVEQARQAAADNLAEARRFVAALAPQDLEGTTLAGALERLCATTSATAPLTVRFHLAHDPGPLPAAYEVALLRIAQAALGNTVRHAGARTAEVTLSGLGDAVALDVVDDGRGFDPAALPAPDPDRGGFGIPAMRARTRALGGTLTIESRPGGGTAVAAQLPLPAEGTRPRPGPEPDPDPVPEAPR
>NZ_CP047147.1|WP_159312836.1|4120898_4121807_+|zinc-binding-dehydrogenase
MRALVVEHGSSGPVRFAEVEEPVPSRDQALVAIRHIGLNFGELNYVDQWPAGAVHGHDASGVVVRAAADGSGPPEGTRVALGMSAHAWAERVAVDPASLAAVPEGVELADGAAPGIAGVTALRVLRTRSLLARDVLITGAGGGVGRFAVQLAALAGARVTALVGSPDRAAGLRALGADEVLTGLAGTESRFDLVLDTVGGPLLAQAWDRLAEGGTLHAVGYSSGQDTTFPSGTLFGFGAPRTLATFGDMTPTSADLTELLDLMAAGKLSAPVGRRGVWQDVDDAVQALFARKVHGKIVLDVV

Crispr_ID: NZ_CP047147_23

• CRISPR_ID: NZ_CP047147_23
• CRISPR_location: 4173668-4173751
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP047147_23

Consensus_repeat	Method
TGGCCTCAAGCGCCGGCCGGGCT	CRISPRCasFinder

spacers of NZ_CP047147_23

>23.1|4173691|38|NZ_CP047147|CRISPRCasFinder
GTGTGTGGTGCGGCCCGCTTCGATGCGCGCGTCACCGA

CRISPR arrays and Neighbor proteins around NZ_CP047147_23

CRISPR arrays

The CRISPR arrays of NZ_CP047147_23

>merge|NZ_CP047147|23|4173668-4173751|CRISPRCasFinder
TGGCCTCAAGCGCCGGCCGGGCTGTGTGTGGTGCGGCCCGCTTCGATGCGCGCGTCACCGATGGCCTCAAGCGCCGGCCGGGCT

>NZ_CP047147|23|19|4173668-4173751|CRISPRCasFinder
TGGCCTCAAGCGCCGGCCGGGCT	GTGTGTGGTGCGGCCCGCTTCGATGCGCGCGTCACCGA
TGGCCTCAAGCGCCGGCCGGGCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_008412057.1|4170847_4171435_-|flavin-reductase	unknown	unknown	gnl|CDD|214900
NZ_CP047147.1|WP_159312859.1|4167682_4168858_-|alcohol-dehydrogenase-catalytic-domain-containing-protein	unknown	unknown	gnl|CDD|176242
NZ_CP047147.1|WP_159313938.1|4164860_4166216_+|M1-family-peptidase	unknown	unknown	gnl|CDD|341066
NZ_CP047147.1|WP_003949940.1|4176087_4177017_-|1-phosphofructokinase-family-hexose-kinase	unknown	unknown	gnl|CDD|274464
NZ_CP047147.1|WP_018893866.1|4181814_4182012_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159312860.1|4174088_4175069_+|carbohydrate-binding-protein	unknown	unknown	gnl|CDD|271149
NZ_CP047147.1|WP_003949939.1|4175170_4176016_-|class-II-fructose-bisphosphate-aldolase	unknown	unknown	gnl|CDD|376459
NZ_CP047147.1|WP_018893863.1|4168857_4169430_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|235142
NZ_CP047147.1|WP_159312858.1|4164132_4164642_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_003949944.1|4180609_4181542_-|ROK-family-protein	unknown	unknown	gnl|CDD|224851
NZ_CP047147.1|WP_159312861.1|4178369_4179275_-|MerR-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl|CDD|133378
NZ_CP047147.1|WP_003949934.1|4169570_4170146_-|TerD-family-protein	unknown	unknown	gnl|CDD|376767
NZ_CP047147.1|WP_159312862.1|4182486_4182819_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_003949943.1|4179434_4180610_-|N-acetylglucosamine-6-phosphate-deacetylase	unknown	unknown	gnl|CDD|238434
NZ_CP047147.1|WP_010643448.1|4163677_4164028_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_015507378.1|4177181_4178129_-|lytic-polysaccharide-monooxygenase	unknown	unknown	gnl|CDD|376983
NZ_CP047147.1|WP_159313939.1|4166222_4167545_-|VCBS-repeat-containing-protein	unknown	unknown	gnl|CDD|379232
NZ_CP047147.1|WP_008412054.1|4171853_4173584_+|diguanylate-cyclase	unknown	unknown	gnl|CDD|143635
NZ_CP047147.1|WP_008412557.1|4182943_4183867_-|SIS-domain-containing-protein	unknown	unknown	gnl|CDD|225132
NZ_CP047147.1|WP_018893864.1|4170347_4170815_+|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl|CDD|181730

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_008412057.1|4170847_4171435_-|flavin-reductase	gnl|CDD|214900	smart00903, Flavin_Reduct, Flavin reductase like domain. This entry represents the FMN-binding domain found in NAD(P)H-flavin oxidoreductases (flavin reductases), a class of enzymes capable of producing reduced flavin for bacterial bioluminescence and other biological processes. This domain is also found in various other oxidoreductase and monooxygenase enzymes... This domain consists of a beta-barrel with Greek key topology, and is related to the ferredoxin reductase-like FAD-binding domain. The flavin reductases have a different dimerisation mode than that found in the PNP oxidase-like family, which also carries an FMN-binding domain with a similar topology.	4.7427e-45
NZ_CP047147.1|WP_159312859.1|4167682_4168858_-|alcohol-dehydrogenase-catalytic-domain-containing-protein	gnl|CDD|176242	cd08282, PFDH_like, Pseudomonas putida aldehyde-dismutating formaldehyde dehydrogenase (PFDH). Formaldehyde dehydrogenase (FDH) is a member of the zinc-dependent/medium chain alcohol dehydrogenase family. Unlike typical FDH, Pseudomonas putida aldehyde-dismutating FDH (PFDH) is glutathione-independent. PFDH converts 2 molecules of aldehydes to corresponding carboxylic acid and alcohol. MDH family uses NAD(H) as a cofactor in the interconversion of alcohols and aldehydes, or ketones. Like the zinc-dependent alcohol dehydrogenases (ADH) of the medium chain alcohol dehydrogenase/reductase family (MDR), these tetrameric FDHs have a catalytic zinc that resides between the catalytic and NAD(H)binding domains and a structural zinc in a lobe of the catalytic domain. Unlike ADH, where NAD(P)(H) acts as a cofactor, NADH in FDH is a tightly bound redox cofactor (similar to nicotinamide proteins). The medium chain alcohol dehydrogenase family (MDR) has a NAD(P)(H)-binding domain in a Rossmann fold of an beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit.	1.45437e-167
NZ_CP047147.1|WP_159313938.1|4164860_4166216_+|M1-family-peptidase	gnl|CDD|341066	cd09603, M1_APN_like, Peptidase M1 family similar to aminopeptidase N catalytic domain. This family contains mostly bacterial and some archaeal M1 peptidases with smilarity to the catalytic domain of aminopeptidase N (APN; CD13; alanyl aminopeptidase; EC 3.4.11.2), a type II integral membrane protease belonging to the M1 gluzincin family. APN preferentially cleaves neutral amino acids from the N-terminus of oligopeptides and, in higher eukaryotes, is present in a variety of human tissues and cell types (leukocyte, fibroblast, endothelial and epithelial cells). APN expression is dysregulated in inflammatory diseases such as chronic pain, rheumatoid arthritis, multiple sclerosis, systemic sclerosis, systemic lupus erythematosus, polymyositis/dermatomyosytis and pulmonary sarcoidosis, and is enhanced in tumor cells such as melanoma, renal, prostate, pancreas, colon, gastric and thyroid cancers. It is predominantly expressed on stem cells and on cells of the granulocytic and monocytic lineages at distinct stages of differentiation, thus considered a marker of differentiation. Thus, APN inhibition may lead to the development of anti-cancer and anti-inflammatory drugs. APNs are also present in many pathogenic bacteria and represent potential drug targets. Some APNs have been used commercially, such as one from Lactococcus lactis used in the food industry. APN also serves as a receptor for coronaviruses, although the virus receptor interaction site seems to be distinct from the enzymatic site and aminopeptidase activity is not necessary for viral infection. APNs have also been extensively studied as putative Cry toxin receptors. Cry1 proteins are pore-forming toxins that bind to the midgut epithelial cell membrane of susceptible insect larvae, causing extensive damage. Several different toxins, including Cry1Aa, Cry1Ab, Cry1Ac, Cry1Ba, Cry1Ca and Cry1Fa, have been shown to bind to APNs; however, a direct role of APN in cytotoxicity has been yet to be firmly established.	1.48646e-154
NZ_CP047147.1|WP_003949940.1|4176087_4177017_-|1-phosphofructokinase-family-hexose-kinase	gnl|CDD|274464	TIGR03168, 1-PFK, hexose kinase, 1-phosphofructokinase family. This family consists largely of 1-phosphofructokinases, but also includes tagatose-6-kinases and 6-phosphofructokinases.	6.78738e-106
NZ_CP047147.1|WP_159312860.1|4174088_4175069_+|carbohydrate-binding-protein	gnl|CDD|271149	cd04083, CBM35_Lmo2446-like, Carbohydrate Binding Module 35 (CBM35) domains similar to Lmo2446. This family includes carbohydrate binding module 35 (CBM35) domains that are appended to several carbohydrate binding enzymes. Some CBM35 domains belonging to this family are appended to glycoside hydrolase (GH) family domains, including glycoside hydrolase family 31 (GH31), for example the CBM35 domain of Lmo2446, an uncharacterized protein from Listeria monocytogenes EGD-e. These CBM35s are non-catalytic carbohydrate binding domains that facilitate the strong binding of the GH catalytic modules with their dedicated, insoluble substrates. GH31 has a wide range of hydrolytic activities such as alpha-glucosidase, alpha-xylosidase, 6-alpha-glucosyltransferase, or alpha-1,4-glucan lyase, cleaving a terminal carbohydrate moiety from a substrate that may be a starch or a glycoprotein. Most characterized GH31 enzymes are alpha-glucosidases.	3.95267e-13
NZ_CP047147.1|WP_003949939.1|4175170_4176016_-|class-II-fructose-bisphosphate-aldolase	gnl|CDD|376459	pfam01116, F_bP_aldolase, Fructose-bisphosphate aldolase class-II.	1.48345e-102
NZ_CP047147.1|WP_018893863.1|4168857_4169430_-|GNAT-family-N-acetyltransferase	gnl|CDD|235142	PRK03624, PRK03624, putative acetyltransferase; Provisional.	8.97629e-08
NZ_CP047147.1|WP_003949944.1|4180609_4181542_-|ROK-family-protein	gnl|CDD|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	1.99041e-59
NZ_CP047147.1|WP_159312861.1|4178369_4179275_-|MerR-family-DNA-binding-transcriptional-regulator	gnl|CDD|133378	cd00592, HTH_MerR-like, Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators. Helix-turn-helix (HTH) MerR-like transcription regulator, N-terminal domain. The MerR family transcription regulators have been shown to mediate responses to stress including exposure to heavy metals, drugs, or oxygen radicals in eubacterial and some archaeal species. They regulate transcription of multidrug/metal ion transporter genes and oxidative stress regulons by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	2.84491e-19
NZ_CP047147.1|WP_003949934.1|4169570_4170146_-|TerD-family-protein	gnl|CDD|376767	pfam02342, TerD, TerD domain. The TerD domain is found in TerD family proteins that include the paralogous TerD, TerA, TerE, TerF and TerZ proteins It is found in a stress response operon with TerB and TerC. TerD has a maximum of two calcium-binding sites depending on the conservation of aspartates. It has various fusions to nuclease domains, RNA binding domains, ubiquitin related domains, and metal binding domains. The ter gene products lie at the centre of membrane-linked metal recognition complexes with regulatory ramifications encompassing phosphorylation-dependent signal transduction, RNA-dependent regulation, biosynthesis of nucleoside-like metabolites and DNA processing linked to novel pathways.	2.98915e-117
NZ_CP047147.1|WP_003949943.1|4179434_4180610_-|N-acetylglucosamine-6-phosphate-deacetylase	gnl|CDD|238434	cd00854, NagA, N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to amino-sugar-nucleotides, which is needed for cell wall peptidoglycan and teichoic acid biosynthesis. Deacetylation of N-acetylglucosamine is also important in lipopolysaccharide synthesis and cell wall recycling.	2.88918e-150
NZ_CP047147.1|WP_015507378.1|4177181_4178129_-|lytic-polysaccharide-monooxygenase	gnl|CDD|376983	pfam03067, LPMO_10, Lytic polysaccharide mono-oxygenase, cellulose-degrading. This domain is found associated with a wide variety of cellulose binding domains. This is a family of two very closely related proteins that together act as both a C1- and a C4-oxidising lytic polysaccharide mono-oxygenase, degrading cellulose. This domain is also found in baculoviral spheroidins and spindolins, protein of unknown function.	6.93097e-51
NZ_CP047147.1|WP_159313939.1|4166222_4167545_-|VCBS-repeat-containing-protein	gnl|CDD|379232	pfam13517, VCBS, Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella. This domain of about 100 residues is found in multiple (up to 35) copies in long proteins from several species of Vibrio, Colwellia, Bradyrhizobium, and Shewanella (hence the name VCBS) and in smaller copy numbers in proteins from several other bacteria. The large protein size and repeat copy numbers, species distribution, and suggested activities of several member proteins suggests a role for this domain in adhesion (TIGR).	4.21104e-07
NZ_CP047147.1|WP_008412054.1|4171853_4173584_+|diguanylate-cyclase	gnl|CDD|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	5.07771e-42
NZ_CP047147.1|WP_008412557.1|4182943_4183867_-|SIS-domain-containing-protein	gnl|CDD|225132	COG2222, AgaS, Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane].	5.64887e-39
NZ_CP047147.1|WP_018893864.1|4170347_4170815_+|aminoacyl-tRNA-hydrolase	gnl|CDD|181730	PRK09256, PRK09256, aminoacyl-tRNA hydrolase.	2.19813e-57

Protein sequences

>NZ_CP047147.1|WP_008412054.1|4171853_4173584_+|diguanylate-cyclase
METESEPYVRLATLRQLHQVIADLNSARSLADTLQTVADGVVTGLGYELSAVNLVQADGDLVVAAVAGNSSAEALLTGQVGPRHAWDHRLSLAEHWGDLRFISHTEAWQLDEDGVPGWYTPAPVPRYEDEWHPGDRLFAPLHVTGSDELLGVISVDRPRNGRLPGPWGQEAFQMYAFQAAIAISNARLRANMQRALVRLEREQQALRASEESFRQAFEFAPSGMAIAEMGGDQHGRILRANDALCRLLGRRAGTLRRYTFSDLAHPEDIGTLLRTSAEGGRTEVRLSTSEGAYLWVSLRNSVVADATDGPRLLLTHVEDITERKRHEMQLAHRASHDALTGLPNSAELRARLSARLCTRPHAGRPSAVDTLDAAYGGPAPGSFPGPAADPDAYDADAHDFDLGLGLGGARHAAGPTGAGFGVAPYEHHVHTVAPDEDGDQDGEGAKGLAVLFCDLDGFKSINDRFGHHTGDAVLIEVARRLTSGVRDGDTVARLGGDEFVVLADGLCHADAQDLAVRLRNAIIPPIRVDGRAVRVGASFGIGWAHCGMSVEEVLQSADQRMYIEKRSRSKQQRRAG
>NZ_CP047147.1|WP_008412057.1|4170847_4171435_-|flavin-reductase
MFTTRATSGSPASAVPAAPSAGPGHAEGVSNEEFRAAMSRLAAGVVLVTAHDPEDGPRGEDAGMTATAFVSVSLDPPLVMVSVRTGSRMDDVLTDRPLWAVSLLGEDQRDIAGRFAMSGRLSDSLLFASLPHTRGEFTGAPLIEGGLGAVECRTEQRVQAGDHTLLIGRVLSAALPAAEGGPLVYYRGRYRHLGR
>NZ_CP047147.1|WP_018893864.1|4170347_4170815_+|aminoacyl-tRNA-hydrolase
MSTDRKPGTPKPAPTGGRVIRGSVVLPDSELTWRFSRSSGPGGQHVNTSDSQVELRFDLAATQALPEVWKERALERLAGRLTGGVLAVRASDHRSQWRNRETALDRMVSLLGEATAPPPRQRRATRIPRGINERRLREKKQRSEVKKNRGRGGDW
>NZ_CP047147.1|WP_003949934.1|4169570_4170146_-|TerD-family-protein
MAVSLSKGGNVSLTKEAPGLTAVTVGLGWDVRTTTGTDFDLDASAIAVNAEGKVYSDGHFVFFNNKQTPDQTIVHTGDNRTGEGDGDDEAINVNLAGLPADVDKIVFPVSIYDAESRSQNFGQVRNAYIRIVNQAGGTEIARYDLSEDAATETAMVFGELYRNGAEWKFRAVGQGYASGLVGIAQDFGVNV
>NZ_CP047147.1|WP_018893863.1|4168857_4169430_-|GNAT-family-N-acetyltransferase
MAAMYVDIVTPDDAALPGALLTEITGVYASAQAFHELTGDFPDAGDIRVPQVAAALADELAVPGSVVHLARVRGELVAVAVTLDHHPADPDDPDPWIGLLLVHGERRREGHGRALAGHLAARFREAGRTGLRLAVLDTNTAALTFWQALGYVPVDHRPDLRRGRECTVLRLPLAASREGRAEAGATAGES
>NZ_CP047147.1|WP_159312859.1|4167682_4168858_-|alcohol-dehydrogenase-catalytic-domain-containing-protein
MRAVVYEGERRVAVREVEDAVVEEETDALVRITSSALCGTDLHMYDGRTGAEPGLVLGHEPLGVVEATGSAVTSVRPGDRVVLPTHLYCGTCPHCAQGLTAACSRVRPGGFGAAYGYAGMGPYRGAQAELLRVPFADANCVPLPGEPGDPFEDAFVLLADAFVTGWHATELAGVGPGDSVAVFGAGTVGLLAAHSALLRGAGEVYVVDHVPARLAVAAEFGAVAVDFTAGDPVEQIRVHRRARGLPPGEAGTGGVDRGIDAVGFQARDRADPARENPAQVVDDLARLVNPTGSLGIAGVYAAKDLHPAAPAGHRDGSLRVPWAQLFDKGVRVGFGRTHDRRYTRLLRDLILDGRAHPERVVTHHGTLDDAPDFYAAFDRREDGMVKAVLRP
>NZ_CP047147.1|WP_159313939.1|4166222_4167545_-|VCBS-repeat-containing-protein
MFRRPGGRHVLVTVLVAVAVLAYLVLLPSDEVAPVPGSPCRADGPARTDPLLAPDLDGDGFGELVYEDAREPDGFQVVVVPGSARGPDAARATVLDRDDLGVPDSVQSIDDTWRPTVADLDGDGHLDLVVSGAAQVVWGGPDGPRADGPRGRVPLPGGPYAGAPVAGDVDGDGHLDLVAYRFTAENPGLVVLKGPFERSGAPADTVEIPTPVNEAASPALLLGDADGDRAADLAVYDSPYDPPLLLSGGADTPSGLSDKPQRLPAGESVAFGDFDGDGRRDIAVGQSFVDPYDEEETPYRRGQVRIAYGKEPGTWVTVEGGAPQEGFGTRLGAGDFDGDGCDDLAVQLTRKKEAADARFAVLHGGSDHGLASEPWRTVRRTVAEPSGPVDDGPVEGSLFAAADWDGDGHAELALAGGGHWWFTDGTDRDTASFPEPGRAG
>NZ_CP047147.1|WP_159313938.1|4164860_4166216_+|M1-family-peptidase
MHGTPGAAGVLDPLFPRLGNGGYDVRHYDLALDWAPATSGERAEQPLRGTARITSRATQNLSAFNLDLKGLEVTSVTVDGRPARYGQAGTELTVRPEKELDKGATFRTTVEYAGRPGPLEDADGSEEGWLTGKAGTVALGEPSGAMTWFPGNHHPLDKATYTLRATVPKGQRAVSGGEPETLEPKPRADGRTTWTWNSRRPMASFLTTLAIGRYELSTGRASSDLPLVNAVAPGEDAEVLERLPEVLDWSVERFGAYPFDSYGALVLDPGTAGYALETQTRPVYPGAPGVGLVVHETAHQWFGNSVTPRTWQDIWLSEGFATYAEWLWEEDHDGPTAQSTFDRLYATSEDADLWAFPPADPPGPDDLFSDPVYQRGAMTLHQVRRLLGEDRFARLLTGWPKKHAYGHARTADFTAYAESLAPDTATREALTRTWAAWLRAEGKPDSARPGR
>NZ_CP047147.1|WP_159312858.1|4164132_4164642_-|hypothetical-protein
MLDIGYALSSRFPDPSDLDYARVDRHALRHDLFCGDVYLADTKADRELSTAWGWVPVLDFAWALCDIVEQVDQDPRGSRASRPQYAELDFTESSDRMLFTRRFGWVDIEADWMKADEPPLTFSHTELRREARDFLHDVVADLCDLHDSLADNPVVWDLQARFPRLPTPR
>NZ_CP047147.1|WP_010643448.1|4163677_4164028_-|hypothetical-protein
MNHSHAAPGTTRMTPHRARPPRRGNTKYPLSPSTVRVLRWGRWFSLTLAVLTWAVVITALVTGSWGADLFLLVTNAVGAVLWPAHAAWSFHALRRHRAAVAAAGAVDHADRADAVV
>NZ_CP047147.1|WP_159312860.1|4174088_4175069_+|carbohydrate-binding-protein
MTPGPGNNGASGDNGTPEGDDPFGYLYADGQAAGATPPGGGGGYGYPGPRSSYNQVRAVGERRYGGQQAQGQQGGYGYPPQQQPYGQAPQGVPPQQQHGAPPPVAPGGGRGRGSGSGGPNTRMLLIGAVAVVVAVIVVIAVTMFSGDDDKGDEAGKDTAPTADAGGGEGEDEQQEKPQEDEEDKPVDLPKTDAKALKLEGGTVTASDIQGAEAGTYVAGFNKVGAKVTWTVNGIPEDAGYSLRVSYGVPGKAANATILVNGKAQERPLNMDNFANVEEGEWSDKWVNTWAVVNLTKGTNTITLSCEEGNQCDANFDQLWLKEGTQG
>NZ_CP047147.1|WP_003949939.1|4175170_4176016_-|class-II-fructose-bisphosphate-aldolase
MPLVPTGELVTEAAAAGRAVAAFNVITLEHAEAVAAAAEEAGLPAVLQISQNAVAYHGHRLGPIAAATGAVARCSTAPLALHLDHADSWELVEAAPAEGFGSVMYDASRLNAEENLRRTAEAVRFGHAHGLWVEAELGRIGGKPGEPPLDAHAPGVRTDPAEAAAYVKETGVDALAVAVGSSHAMTERTAALDHTLIAALRSAVPVPLVLHGSSGVPDEELAHAVRSGMTKINIGTALNQAFTSALTTHLTDHPDPRPYLSLARAAVRGRAHHFLTVLSGV
>NZ_CP047147.1|WP_003949940.1|4176087_4177017_-|1-phosphofructokinase-family-hexose-kinase
MILTVTLNTAVDLTYHVPTLRQHTTHRVTETQDRPGGKGVNVARVLARLGHPTTVTGFAGGPTGAWLREALSGEPHLKDALVPIGGTTRRTVAVVDAAGGDTTQFNEPGPTVTAAEWEALKKAYASLLPGAEAVALCGSLPPGVPVGAYAHLIREARSAGVPVLLDTSGEPLRRGIAARPDLVKPNAAELADLTGTRDPRHAARAARRRGARAVVASLGAEGLLAETPVGAWRAAPPGPVRGNPTGAGDSVVAGLLAGLAEGADWPDRLVRAAALSAATVHASAAGEYDEAAYRDLAARITATALPGAA
>NZ_CP047147.1|WP_015507378.1|4177181_4178129_-|lytic-polysaccharide-monooxygenase
MAIHSIRTRHTLALAAAAGVAAAVLSVPSPASAHGVSIMPGSRTNLCYKDLLQNSSTQMPSNPACADAVRQTGTTPLYNWFAVLDSNAGGRGAGYVPDGKLCSAGDRSPYDFSAYNAVRTDWPKTHLTSGATIQLKYSNWAAHPGKFEVYLTKSGWNPNQALAWGDLDHLQTVTDPPQNGGVGTNEGHYYWNLPLPQRSGQHMLFIQWIRSDSQENFFSCSDVVFDGGSGEVTGLAGGEQSAAEVEALGADVENTKADPIHAAGHTEHAAAGEELAASGNEAAGAVPAVVAGLGAVVFAGGAMVFNRSRRTRQHG
>NZ_CP047147.1|WP_159312861.1|4178369_4179275_-|MerR-family-DNA-binding-transcriptional-regulator
MYPSLTPPRQVKIGDAAAFAGTTPRAIRHYHAIGLLPEPERGGDGRRRYGYDDMIRLLWIRKMADAGISLDDMRAAFGEARDETRDESGDEASDQAPGIESVLGRLEESLAAQEAAVRRRRAAVQRLRAVGSPLGLLSELVTDRLSPLPPGALRPSDLDALLVTERICGPLGAAIQASAFIVLATHPDLRAEDDRLEAAEAALDDGVAPDDPRVEELAVQRCAHQMALDQAIEAAGLEAAEAKILETYDAGLTGEEGREMSAATAVTKMPYDFSPARMRCLELAGRLFGEALADAHPADGS
>NZ_CP047147.1|WP_003949943.1|4179434_4180610_-|N-acetylglucosamine-6-phosphate-deacetylase
MAAPARKVLTGARVVLPSGTVDDGEVVIDGAHIGGSAPSAGQEGEAERWDLSGHWIVPGFVDLHNHGGGGASFTSGTVDDVLTGIATHRAHGTTTLVASTVTGEMDFLTARAGLLSELTEQGDLAGIHFEGPFISPCRKGAHSEALLRDPHPADVAALLDASRGAARMVTLATELPGGLDSVRLLADRGVIAAVGHTDATYEQTVEAIDAGATVATHLFNAMPPLGHRAPGPIAALLEDERVTVELINDGTHLHPAALELAFHRAGADRVAFITDAMDAAGFGDGRYLLGPLEVDVVDGVARLVEGGSIAGSTLTLDRAFRRAALVDKLPVDQIVRALSANPARLLGLDHRIGSLEPGKDADLVVLDEGFEVKGVLRHGDWVVAPQVAAAA
>NZ_CP047147.1|WP_003949944.1|4180609_4181542_-|ROK-family-protein
MRHVIALDVGGTGMKAALVGPDGELLHEARRDTGRDRGPDAVVASILDFADALRAHGLAEFGEQAAAAGVAVPGIVDTEKGVAVYAANLGWSDVPLRDMLTARLGGTPVALGHDVRTGGLAEGRIGAGRGADRFLFMPLGTGIAGAIGINGVIEPGAHGSAGEIGHVVIRPGGIPCGCGQRGCLERLASASAVSLAWAEASGDPEADAADCARAVAAGDPRAVAVWQEAVDALADGLVMAVTLLDPRTLIIGGGLAEAGETLFTPLRAAVEERVTFQKLPTIVPAALGDTAGCLGAGLLAWDLLATEVSA
>NZ_CP047147.1|WP_018893866.1|4181814_4182012_-|hypothetical-protein
MSPEPLKMLWLVVGLLFACLVGLFAIVAKIIFDPRSTAWARVTTGAGAWVVAMGLVISLAALFVP
>NZ_CP047147.1|WP_159312862.1|4182486_4182819_-|hypothetical-protein
MPYSFLLRLLPTETPPHLYRATVHNADGTHEAFLLLTPDPPSVHLADARGNPSGGLRMSLADGTVERTDAEPQEARCSLGAEDFRTLAAHLLTQYGKQGRPPEEIRRVFA
>NZ_CP047147.1|WP_008412557.1|4182943_4183867_-|SIS-domain-containing-protein
MSRTAAEITTQPACWRRAAEEAARFTAAPRPGERVAVVGCGTSWFMAQSYAALREGAGQGATDAFAASEFPRARAVGAYDRVVALTRSGTTTEVLELLALVRAAGTATVALTADPATPVMTAADEVAVLDWADEESVVQTRFATTALAFLRATLGDLPGLASVPRAADDAEHAVTEPLPRPLLTAGQWTFLGRGWAYGLAQEAALKMREAAGAWTESYPAMEYRHGPIAITAPGRVTWLFGEAPAGLADDVHRVGGHFEHHPTTDPLADLIRAQRLAVALAEAQGHNPDRPRNLTRSVVLATDDGRH

Crispr_ID: NZ_CP047147_24

• CRISPR_ID: NZ_CP047147_24
• CRISPR_location: 4272824-4273093
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NZ_CP047147_24

Consensus_repeat	Method
ACAGCCCGGCCGGCGATTGAGGCCA	PILER-CR

spacers of NZ_CP047147_24

>24.1|4272849|63|NZ_CP047147|PILER-CR
TCAGTGACCCGCAGGGTCGAGACGGGCAGGTGGAGGCGGAGCCCAGCCACCACCCGCCCAATC
>24.2|4272937|56|NZ_CP047147|PILER-CR
GTCAGTGACCCGGCACGGGCAACAACCGGCACCCCCAGTCGCGGCGCAGCCACACC
>24.3|4273018|51|NZ_CP047147|PILER-CR
CCGGGACCGGCAGGGGCGAGGCCGGTAGATCGGGGCGGAGTCCGGCAACCG

CRISPR arrays and Neighbor proteins around NZ_CP047147_24

CRISPR arrays

The CRISPR arrays of NZ_CP047147_24

>merge|NZ_CP047147|24|4272824-4273093|PILER-CR
ACAGCCCGGCCGGCGATTGAGGCCATCAGTGACCCGCAGGGTCGAGACGGGCAGGTGGAGGCGGAGCCCAGCCACCACCCGCCCAATCACAGCCCGGCCGGCGATTGAGGCCAGTCAGTGACCCGGCACGGGCAACAACCGGCACCCCCAGTCGCGGCGCAGCCACACCCCAGCCCGGCCGGCGCTTGAGGCCACCGGGACCGGCAGGGGCGAGGCCGGTAGATCGGGGCGGAGTCCGGCAACCGACAGCCCGGCCGGCGATTGAGGCCA

>NZ_CP047147|24|6|4272824-4273093|PILER-CR
ACAGCCCGGCCGGCGATTGAGGCCA	TCAGTGACCCGCAGGGTCGAGACGGGCAGGTGGAGGCGGAGCCCAGCCACCACCCGCCCAATC
ACAGCCCGGCCGGCGATTGAGGCCA	GTCAGTGACCCGGCACGGGCAACAACCGGCACCCCCAGTCGCGGCGCAGCCACACC
CCAGCCCGGCCGGCGCTTGAGGCCA	CCGGGACCGGCAGGGGCGAGGCCGGTAGATCGGGGCGGAGTCCGGCAACCG
ACAGCCCGGCCGGCGATTGAGGCCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_159312894.1|4262912_4264844_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|224055
NZ_CP047147.1|WP_033240380.1|4280216_4282655_-|HAD-IC-family-P-type-ATPase	unknown	unknown	gnl|CDD|319795
NZ_CP047147.1|WP_003950021.1|4266745_4267129_+|cold-shock-protein	unknown	unknown	gnl|CDD|224197
NZ_CP047147.1|WP_008406155.1|4271384_4272245_+|DUF3027-domain-containing-protein	unknown	unknown	gnl|CDD|378605
NZ_CP047147.1|WP_008404125.1|4279250_4280111_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_008404117.1|4284966_4285230_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159312896.1|4277647_4278907_-|cytochrome-P450	unknown	unknown	gnl|CDD|225035
NZ_CP047147.1|WP_107060929.1|4269506_4270973_-|MFS-transporter	unknown	unknown	gnl|CDD|340863
NZ_CP047147.1|WP_003950032.1|4283447_4284893_+|NCS2-family-permease	unknown	unknown	gnl|CDD|225161
NZ_CP047147.1|WP_159312893.1|4261002_4262916_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|224055
NZ_CP047147.1|WP_008404115.1|4285969_4287316_+|MFS-transporter	unknown	unknown	gnl|CDD|340863
NZ_CP047147.1|WP_003950020.1|4266352_4266604_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_008415563.1|4268952_4269477_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_003950034.1|4285428_4285866_+|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NZ_CP047147.1|WP_159312895.1|4273328_4276562_+|molecular-chaperone-Hsp90	unknown	unknown	unknown
NZ_CP047147.1|WP_159313941.1|4265333_4266044_-|DNA-binding-response-regulator	unknown	unknown	gnl|CDD|225107
NZ_CP047147.1|WP_159313942.1|4268206_4268932_-|futalosine-hydrolase	unknown	unknown	gnl|CDD|350166
NZ_CP047147.1|WP_159312897.1|4287394_4287985_+|RNA-2',3'-cyclic-phosphodiesterase	unknown	unknown	gnl|CDD|274058
NZ_CP047147.1|WP_010643321.1|4282823_4283090_-|DUF2530-domain-containing-protein	unknown	unknown	gnl|CDD|378488
NZ_CP047147.1|WP_003950022.1|4267245_4268139_-|1,4-dihydroxy-6-naphthoate-synthase	unknown	unknown	gnl|CDD|270353

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_159312894.1|4262912_4264844_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	3.31446e-44
NZ_CP047147.1|WP_003950034.1|4285428_4285866_+|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.04287e-20
NZ_CP047147.1|WP_003950021.1|4266745_4267129_+|cold-shock-protein	gnl|CDD|224197	COG1278, CspC, Cold shock proteins [Transcription].	5.07314e-27
NZ_CP047147.1|WP_008406155.1|4271384_4272245_+|DUF3027-domain-containing-protein	gnl|CDD|378605	pfam11228, DUF3027, Protein of unknown function (DUF3027). This family of proteins with unknown function appears to be restricted to Actinobacteria.	2.60749e-109
NZ_CP047147.1|WP_033240380.1|4280216_4282655_-|HAD-IC-family-P-type-ATPase	gnl|CDD|319795	cd02609, P-type_ATPase, uncharacterized subfamily of P-type ATPase transporter, similar to uncharacterized Streptococcus pneumoniae exported protein 7, Exp7. This subfamily contains P-type ATPase transporters of unknown function, similar to Streptococcus pneumoniae Exp7. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids. They are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle. A general characteristic of P-type ATPases is a bundle of transmembrane helices which make up the transport path, and three domains on the cytoplasmic side of the membrane. Members include pumps that transport various light metal ions, such as H(+), Na(+), K(+), Ca(2+), and Mg(2+), pumps that transport indispensable trace elements, such as Zn(2+) and Cu(2+), pumps that remove toxic heavy metal ions, such as Cd(2+), and pumps such as aminophospholipid translocases which transport phosphatidylserine and phosphatidylethanolamine.	0
NZ_CP047147.1|WP_159312896.1|4277647_4278907_-|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	1.47198e-73
NZ_CP047147.1|WP_159312893.1|4261002_4262916_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	8.49678e-83
NZ_CP047147.1|WP_008404115.1|4285969_4287316_+|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.19265e-82
NZ_CP047147.1|WP_010643321.1|4282823_4283090_-|DUF2530-domain-containing-protein	gnl|CDD|378488	pfam10745, DUF2530, Protein of unknown function (DUF2530). This family of proteins with unknown function appears to be restricted to mycobacteria.	0.00969272
NZ_CP047147.1|WP_003950032.1|4283447_4284893_+|NCS2-family-permease	gnl|CDD|225161	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism].	1.89915e-107
NZ_CP047147.1|WP_107060929.1|4269506_4270973_-|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.948e-26
NZ_CP047147.1|WP_159313941.1|4265333_4266044_-|DNA-binding-response-regulator	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	2.32283e-25
NZ_CP047147.1|WP_159313942.1|4268206_4268932_-|futalosine-hydrolase	gnl|CDD|350166	cd17766, futalosine_nucleosidase_MqnB, futalosine nucleosidase which catalyzes the hydrolysis of futalosine to dehypoxanthinylfutalosine and a hypoxanthine base; similar to Thermus thermophiles MqnB. Futalosine nucleosidase (MqnB, EC 3.2.2.26, also known as futalosine hydrolase) functions in an alternative menaquinone biosynthetic pathway (the futalosine pathway) which operates in some bacteria, including Streptomyces coelicolor and Thermus thermophiles. This domain model belongs to the PNP_UDP_1 superfamily which includes members which accept a range of purine nucleosides as well as the pyrimidine nucleoside uridine. PNP_UDP_1 includes phosphorolytic nucleosidases, such as purine nucleoside phosphorylase (PNPs, EC. 2.4.2.1), uridine phosphorylase (UP, EC 2.4.2.3), and 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP, EC 2.4.2.28), and hydrolytic nucleosidases, such as AMP nucleosidase (AMN, EC 3.2.2.4), and 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase (MTAN, EC 3.2.2.16). Superfamily members have different physiologically relevant quaternary structures: hexameric such as the trimer-of-dimers arrangement of Shewanella oneidensis MR-1 UP, homotrimeric such as human PNP and Escherichia coli PNPII (XapA), homohexomeric (with some evidence for co-existence of a trimeric form) such as E. coli PNPI (DeoD), or homodimeric such as human and Trypanosoma brucei UP. The PNP_UDP_2 (nucleoside phosphorylase-II family) is a different structural family.	8.02478e-67
NZ_CP047147.1|WP_159312897.1|4287394_4287985_+|RNA-2',3'-cyclic-phosphodiesterase	gnl|CDD|274058	TIGR02258, UPF0097_protein_AF_2157, 2'-5' RNA ligase. This protein family consists of bacterial and archaeal proteins with two tandem copies of Pfam domain pfam02834. Members for which activity has been measured perform a reversible, ATP-independent 2'-5'-ligation of what is presumably a non-phyiological substrate: half-tRNA splice intermediates from an intron-containing yeast tRNA. The physiological substrate(s) in prokaryotes may include small 2'-5'-link-containing oligonucleotides, perhaps with regulatory or biosynthetic roles. [Transcription, RNA processing].	2.31308e-36
NZ_CP047147.1|WP_003950022.1|4267245_4268139_-|1,4-dihydroxy-6-naphthoate-synthase	gnl|CDD|270353	cd13635, PBP2_Ttha1568_Mqnd, A menaquinone biosynthetic enzyme exhibits the type 2 periplasmic-binding protein fold. This group includes Ttha1568 (MqnD) from Thermus thermophilies HB8, an enzyme within an alternative menaquinone biosynthetic pathway that catalyzes the conversion of cyclic de-hypoxanthine futalosine to 1,4-dihydroxy-6-naphthoate. Menaquinone (MK; vitamin K) is an essential lipid-soluble carrier that shuttles electrons between membrane-bound protein complexes in the electron transport chain. Ttha1568 has significant structural homology with the members of type 2 periplasmic-binding fold protein superfamily. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	2.21409e-142

Protein sequences

>NZ_CP047147.1|WP_008406155.1|4271384_4272245_+|DUF3027-domain-containing-protein
MSAATTRSRTPDRLCAEAVDLARSVAEETAAPGVVGEHLAVTADGDRVATHYFACHDPGYRGWRWAVTVARASRAKYVTVDESVLLPGPDALLAPEWVPWSERLRPGDLGPGDLLPTEADDLRLEPGWIADEEPPPNSAVSADMAELVEAEDASLSAGPPADLPLAPERGSVASVAEELGLRRSRVLSRYGLLDAAERWEAQFGAESAMAQAAPAPCVSCGFLLPLAGSLRQAFGICANAYSPADGHVVSLAYGCGGHSEAAVMPTPPRPPDPALDETRLDPLPLD
>NZ_CP047147.1|WP_107060929.1|4269506_4270973_-|MFS-transporter
MRRAARVVGRALRTPVTGPARGIRKVTHAQGAGESGLGRLIELHGVNGAGDVMITVALASTVFFSVPTDEARGRVALYLAVTMLPFTLLAPVVGPLLDRLPHGRRAAMAGSMLARAVLALVLSGAVATGSLEMYPAALGVLVASKAYGVVRSAVVPRLLPQGFSLVKANSRVTLGGLLATGVAAPVGAGLQMIGPGWPLYGACLLFLGGAFLSFRLPPKVDSARGERRALLAADEQHLAAAVDARWDPVTTDDKTDDKTDSTDNKEEEKDRDGERGDGERGKGKERRRKGPGLRTVGPAVTHALAANACVRCQSGFLIFFLAFLLREHPLTGQSAAVSLAVVGVAAGAGNALGTAVGAWLRARAPEVIIVTVVGALVAVAVSAAVFFGAAVVAVLGAVAGFTQALAKLSLDALIQRDVPELVRTSAFARSETLLQMAWVVGGAIGIALPLRGPLGLSVGALIVALGWLTTVRALLASARRGASHPRVA
>NZ_CP047147.1|WP_008415563.1|4268952_4269477_-|hypothetical-protein
MTSLPRGGAARQFSPATRRGFAVLGAVSAGLLVLSACDKPTAVATVTIGSDSVNSEATCWNGGSKIDEKKLQQCLQDKGEGDSGDGAEVKTVKVDTEADVHIGVDPKIADKGWTILMNGQPLTDASNKTFRTIPGSVFFNQQYGASGDSTVLSILENDGSSATGLWSFKLEKES
>NZ_CP047147.1|WP_159313942.1|4268206_4268932_-|futalosine-hydrolase
MRLLVATAVPPERDAVARAFGAPDTPEETALPGAVLLRTPGADVLAAGVGPAAAASATSAALTAARLAGNPYDLVVSAGIGGGFAERAPVGAVVVADRIVAADLGAETPDGFVPVTGLGFGTDVHVPPAALVEAAREAGLVPGAVLTVSTVTGSADRAAELLARHPSAVAEAMEGFGVAEAAAAHGVPVLEIRAISNAIGPRDRDAWRIPAALTALTSAFVRLAPAEAGSPFALARARLVP
>NZ_CP047147.1|WP_003950022.1|4267245_4268139_-|1,4-dihydroxy-6-naphthoate-synthase
MSESGTGGVQGTADEAGRLSIAYSPCPNDTFVFDAVAHGRVPGAPALDVTFADIDLTNGMAERGAYDVLKVSYAALPWLLDEYALLPCGGALGRGCGPLVLTREASLPGALAGRTVAVPSERSTAYLLFRLWAADQVPGGVGEIVVMPFHEIMPAVRDGKVDAGLVIHEARFTYQNYGLHKLADMGEHWEATTGLPIPLGAIIARRSLGAERLTALAQALRTSVRMAWDDPAASRPYVLAHAQEMDADVADQHIGLYVNEFTADLGEDGYAAVRGLLTRAAAEGLVPPLAPDALRFP
>NZ_CP047147.1|WP_003950021.1|4266745_4267129_+|cold-shock-protein
MPTGKVKWFNSEKGFGFLSRDDGGDVFVHSSVLPAGVEALKPGQRVEFGVVAGQRGDQALSVVLLDPAPSVAAAQRRKPDELASIVQDLTTVLENVSRSLERGRYPDRASGAKVAGMLRAVADQLDV
>NZ_CP047147.1|WP_003950020.1|4266352_4266604_-|hypothetical-protein
MSDTTQQTPAPGDRLVKTGGIVFIIGALATLVTVAPLFLGSDPFPTAAYLVSMLMGVGFLIAGAGLVRQIAAQRRETRAAVEG
>NZ_CP047147.1|WP_159313941.1|4265333_4266044_-|DNA-binding-response-regulator
MIHSSGVLRSALVALLERERFQVTSASGFSRASSGATGAPGTPGAPATVTVVDGSCPVGAAHLERRSLQGSAKEPTHATPALAAARPGLGLAGAGAERAGIGLAGASRGRAALVVLAGAEHPGVLRLAYTAGALGLVDRDGPANHLATAIRLAAGGGRYVDDGLAMSLLRAMDMPLSPREVRVLSRAAQGDSVAEIARGLCLSHGTVRNYIASATRKVGARNRVDAIRISRAAGWV
>NZ_CP047147.1|WP_159312894.1|4262912_4264844_+|ATP-binding-cassette-domain-containing-protein
MTRPRHTDGAPSPLLRPALTFARRRKGPLGALGAWSLLESARTFLTGYAVARALDDGFLAGDVRTGLVWLLALGAAAFAGGFADAGVFRALGGVIEPLRDSLVRRVVRVTLTRAVASPTPADTARVSRLTAQTEIARDAAGGVLLTVRSFLFTSAGAFTGLAALSLRLLPLVLIPLAAGLALFAATLRPMAARQRDLLDADEHLAAFAGRTDHAARDIAATGAAPLVTAEAAPLITAEATAASALARWAAVRVTALGLAAHLPVATLLLAAPTLLSTGLTPGELLAALTYVTTALLPAVNALLTALGAAGSRLLVVLHRLLGEEADAADVREEQPHTLRVDDGPRAPGAWSKGKADDEVPAIPAPSLPPEPVHGPEPFRAEPSPPGPRPTRGPRPTRPAPPAATLRGVTFAYGPDAAPVLDHLDLTVEPGEHLLVVGPSGAGKSTLLALLAGTAHPRHGQIHLAGHTARHARTLGTAARVLVPQEPYIFEAPLHDNLTYLAPDAPAPRITEAIHTFTLASLAADPARPLRPDHLTPSERRRIALARAWLTPTPLLLLDEPTAHLDAGARAATELAFASHPATVITVSHHFPAPEPGQRVLLLDGATPYLGTHASLLRESALYGELAAGLGEPSAAGSRGTALT
>NZ_CP047147.1|WP_159312893.1|4261002_4262916_+|ATP-binding-cassette-domain-containing-protein
MTAAPADATRARATPAPPPAEGRLLREAVRRGRGPAALVLAATALGAAAAVTLPLALGRAVDLLIARADAGSWVLLCTALIATEVATDALVARTGGRTGAATTAWLRRRALAGFLAAPPAATTGTGLPTRLTANALDAGTAPVAAATAAAAGLAPLGGLAGLFLVDPWAGAAFVCGVPLLLLILRALLRDGRAALTTYQEEQGRMARLLTGALSGAATIAAAGTVRAEERRVLAPLAGMRAAGERTWRVQGRAAGLSGALMPLLVAAVLAVGGVRLVAGHLTPGDLLALSRYAVLAAGAGALAGALNGWVRAKAGTARVETVTALPPTPHGTRDLPPHGDGTLALHGVHVTRDGVPLLDSVTLTLPGGTTTALVGPSGSGKSLLAAVAGRLTDPDQGTVLLDGTDLRTLSADALRHAVAYAFERPALFGATIADAVACGPLPEPDLRRALRRAAADTFTDRLPHGPRTPLPEAPLSGGELQRLGLARAFTRPTRLLILDDATSSLDTVTAHLVARALTDTPGTRLTITHRLTTAAQSDQVVWLDGGRIRGTGPHSVLWRDPAYRAVFGAGAGAGAGAGGDAGAGADTVTDTGARRRSDVRTDVTGDVRTELPTDMRTDLHTGIRTDPRVDTGTGAAE
>NZ_CP047147.1|WP_159312895.1|4273328_4276562_+|molecular-chaperone-Hsp90
MTHPTPAQEGKDPFGTARRRRTVLDSWAASPARFREDANAEEDLALGGYRDRLIVELAQNAADAASRAGTDGRLRLTLHESAGTHVLAAANTGAPLDATGVESLSTLRASAKRPATGTATGAAPGAGPSVGRFGVGFAAVLAVSDEPAVLSRTGGVRWDLAQAREAAREVARHSPGLGDELIRRDDHVPLLRLPFPAEGTPPEGYDTVVVLPLRDAAAQDLAERLLAAVDDALLLALPGLTEIVVETPESTRALRRRDEEPYVVIEESTGGSGATGSGATGAPAETRRWRTATSGGPLDAPLLADRPVEERLRPYWSVVWAVPVDAEGAPVRPATAPVVHAPTPSDEPLGVPALLIASFPLDTARRHVAPGPLTDFLVGRAAEAYAGLLGAWRPVGPAAVGLVPGPLGLAAVDGAVRAAVLDLLPRTAFLPPALPPAGPDEEPDTDVPLLRADRPEALRPIEAELVEGAGEATVRVLAEVLPTLLPAGLERRAELRTLGVGRLSLGEAIDRLAGVERSPAWWYRLYDSLAGVDPDRLQGLPVPLAAGSTAGSPRQVLLPGPAEDGPRPAALARLGLKVAHPEAAHPLLEKLGALPATPRAVLRTPQVRAAVAESLEGDGYALRDDAPDAEELAELVLTLARDAELAPGDEPWLGALALPDEDGELSPAGELVLPGGEFASVMREGELAAVDEEWAGRWGEQPLAACGVLARFTLVRATDVVLDPDELEPRDSDFAEPDDVGLLDAVDVWCEDVLDQLPDGPVPPVATEITAVRDLDLVDDDRWPEALALLSRPPLRDALTQPVRVLLPDGTTESVRPYTAWWLRGHPVLDGRRPAGLRAASGDALLAGLYDEVDAAGFDDALVLRALGVRTTAAALLDEPGGAAELLDRLADPDREVSARQLHALYGLLAELDPEEVTLPDELRAVADGVVTVVDARDALVADAPDLLPFAAGRPLLPVAPALAARLAELLQVGRLSEAVRVTPAGEGVEYPVPEAVRELLGDGVPASYREHDELLADGVELDWHLTASGVLHAATLEGVAAGLAWGAGQWPRRFEVAALLEDPSRRAELSRDRWFD
>NZ_CP047147.1|WP_159312896.1|4277647_4278907_-|cytochrome-P450
MPSSAPPEQEPLVLDPTGADPHAEHRALHARGPATRVDVLGVPAWSVSDPALLRALLTSPDVSKDGRAHWPAFAETVQSWPLALWIAVRNMFTSYGADHRRLRRIIAPAFSARRVAAVRPVVERITAGLLDDLAALPPDAPVDLREKLAYPLPVAVIGHLMGVPEERYAHFRAVVDGVFDTTLGREEAAANTDALYVVLDELIATRRAEPGDDLTSLLLATPDEEGAEPALSHEELRDTLLLVISAGYETTVNVIDQAVHALLTVDGQLDLVRSGQVGWGDVVEETLRHESAVKHLPLRYAVRDIPLPDGRTIARGEAILASYAAANRHPGWHDDADVFDAGRLSKEHLAFGHGVHFCVGAPLARLEVEVCLRLLFARFPGLALDLPAEGLPPFPSLISNGHRNLPVWLHGGALGEGPG
>NZ_CP047147.1|WP_008404125.1|4279250_4280111_+|hypothetical-protein
MRIRATVAVVSGALALSALTGAAAQAAPGPDRERIQVPTAESVFGKQATAKGKGFKAAAVPKISKVTVNGGKDIVLGTTKAKTFSVSITASHASNIGDAYAYFWHGSTYETADGVFIPNEEYASCKASSATTSTCKLTFTVDPQWELINDLAGSWNVGVGALAADDSDFAWNDKHSKTRVQRYSKLVVNATPEPVKKGKTLTVNGTLSRANWDTWKYAGYTQQSVKLQFKKKGAASYTTVKTVKSGSKGALKTTVKAASDGYWRWSFAGTSTTPAINSTADFVDVK
>NZ_CP047147.1|WP_033240380.1|4280216_4282655_-|HAD-IC-family-P-type-ATPase
MTQRGQVDTGGSDSGNSRIDTGAEPDAAPPAVPPEPGLTSAEVAEAVARGEVNDVPVRSSRSLAEIARANIFTRFNAIIGVLWVIMLFVAPIQDSLFGFVIVANTGIGIFQEWRAKRTLDGLAVIGEAKPTVRRDGRPGEISTSEIVLGDLIEIGPGDKIVVDGEVREADGLEVDESLLTGEADPVVKRPGDEVMSGSFVTAGGGAFRATKVGREAYAAQLAEEASRFTLVHSELRSGISTILKYVTWMMVPTAIGLVVSQLVVRDNDFKNAVARTVGGIVPMVPEGLVLLTSVAFAIGVIRLGRKQCLVQELPAIEGLARVDTVCLDKTGTLTEGGMDVQAIRPLGGADEAYVRRVLGALGAGDPRPNASLQAVIDACPAPEGWRTTGTLPFSSARKYSGASLDEGDATHRTWLLGAPDVLLRPGAEALAETDALNERGLRVLLLSRAAGGLDGPDPGAGAEPTALVVLEQRLRPDAADTLRYFEDQHVAAKVISGDNAVSVGAVAGKLGLPGAERTYDARKLPKEPEALADTLDENTVFGRVTPQQKRDMVGALQAHGHTVAMTGDGVNDVLALKDADIGVSMGSGSEATRAVAQIVLLNNSFSTLPSVVAEGRRVIGNITRVATLFLVKTVYSVLLAILVVLSQTEYPFLPRHLTLLSTLTIGVPAFFLALAPNKERAQPHFVKRVMRYAIPGGVIAALATFTTYMTARAYYTGPDSLPAETSAATLTLFLVSLWVLAIIARPYTWWRVGLVATMAGAFLVVLAVPWLQDFFALRLVGSVMPWAAVGIAVIAAALIEVVWRLVDRRLPV
>NZ_CP047147.1|WP_010643321.1|4282823_4283090_-|DUF2530-domain-containing-protein
MKKWTPRHEAPEPLEGPVVATITGGTILWFVLFLAQLPFYGWYADHGHTWWIWTCLAGAGLGCLGVWYVRRREAALKRAAAAAPQPGS
>NZ_CP047147.1|WP_003950032.1|4283447_4284893_+|NCS2-family-permease
MPTSAPAQDATSEQPNPPSGALDRYFKITERGSTLSREVRGGFATFFAMAYIIVLNPIILGSAKDMYGHQLDNGQLVTATVLTAALTTLLMGVIGNVPVALAAGLGVNTVVALQLAPRMSWPDAMGMVVLAGFVVMLLVATGLRERVMSAVPLGLRKGIAIGIGLFIMLIGLVDAGFVSRIPDAAQTTVPLQLGADGHLNGWTVLVFVLGVLLTLALMVRKVPGAILISIVAMTVLALIINAVADIPSWGLTTPEWPGNPVATPDFGLIGQVSLFGGFAKVGLLTGILFVFTVLLSCFFDAMGTIMAVGDEAELTDAQGNMPGINKVLFVDGIAVAAGGASSSSATTCFVESTAGVGEGARTGFANIVTGGLFAIGLFLTPVVTMVPSQAATPALVAVGFLILSGSIGAIDWTDFTIAIPAFITFMMMPFTYSITNGIGMGFISFCVLRLAAGRGRSVPAAMYVVSGVFAFYYLMPALGLT
>NZ_CP047147.1|WP_008404117.1|4284966_4285230_-|hypothetical-protein
MDTHVLSLRMDSELFERLRGHAARRGMSVQDYVVRTMIRDDFDQRFQTAVEETEKFYGDEDGGAPGAGEVAEEPARDGAVNGAARPT
>NZ_CP047147.1|WP_003950034.1|4285428_4285866_+|MarR-family-transcriptional-regulator
MPDLTHGEDADAVNALRSSVMRLSRRLKHQRVDESLSPTEMSVLGTLARCGTATPGELARKEHVQPPSMTRIVALLEAKGLVRLEPHPEDRRQKVVTQTEEAEAMLEESRSKRNAWLASLAAELDEEEWAKVRAAAPVLEKLAHL
>NZ_CP047147.1|WP_008404115.1|4285969_4287316_+|MFS-transporter
MSTGPGADSAPAPAAHDSTPPAPKQSMFSSLKIHNYRLFFTGQVISNTGTWMQRIAQDWLVLTLTGSSAAVGVTTALQFLPMLLFGLYGGVLVDRLPKRPLLLFTQSAMGLTGLALAALTLTGHVQVWHVYVTAFVLGLVTVVDNPARQTFVSEMVGPRQLANAVSLNSANFQSARLVGPAVAAVLISAVGSGYAFLINGLSFAAPIAGLLMMRMGDLHKAPRTPRGKGQLREGLRYVAGRPDLIWPIVLVGFIGTFGFNFPIWLSAFADKVFDGGPGMYGTLNTLIAAGSLAGALLAARRGAGRLRLLVAAAAAFGVLEIVAAFAPSVWIFAVLMVLTGMFGLTVNVTANSYVQMATEPQMRGRVMALFMMVFTGGTPLGAPLLGWITDEYGARTGFAVGGAISLLAALAVGLILARVGGLKVKVDLRRGRKHIRFVPDEKRLAPAA
>NZ_CP047147.1|WP_159312897.1|4287394_4287985_+|RNA-2',3'-cyclic-phosphodiesterase
MASPAPRPRLFVAVVPPDAVLAELRRATAALDALPGAGRLRPTEAGGRHVTLAFLGACDPGRLDGLAARLARAAHRTAPFPLALRGAGHFGDRVLWARPDGDLDALARLAERVRAAATRAGLPPDAEHAFRPHLTLARVRPGPPLRLAPFAEALAQLAAGPWQADEVRLVRSVPPPGGVPGARPTYATEGRWPLGG

Crispr_ID: NZ_CP047147_25

• CRISPR_ID: NZ_CP047147_25
• CRISPR_location: 4276656-4276759
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP047147_25

Consensus_repeat	Method
TGGCCTCAATCGCCGGCCGGGCTG	CRISPRCasFinder

spacers of NZ_CP047147_25

>25.1|4276680|56|NZ_CP047147|CRISPRCasFinder
GGGTGTGGCTGCGCCGCTCTGGGGGTGCCGGTCGTTGCCCGTGCCCGGTCACTGAC

CRISPR arrays and Neighbor proteins around NZ_CP047147_25

CRISPR arrays

The CRISPR arrays of NZ_CP047147_25

>merge|NZ_CP047147|25|4276656-4276759|CRISPRCasFinder
TGGCCTCAATCGCCGGCCGGGCTGGGGTGTGGCTGCGCCGCTCTGGGGGTGCCGGTCGTTGCCCGTGCCCGGTCACTGACTGGCCTCAATCGCCGGCCGGGCTG

>NZ_CP047147|25|20|4276656-4276759|CRISPRCasFinder
TGGCCTCAATCGCCGGCCGGGCTG	GGGTGTGGCTGCGCCGCTCTGGGGGTGCCGGTCGTTGCCCGTGCCCGGTCACTGAC
TGGCCTCAATCGCCGGCCGGGCTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_159312894.1|4262912_4264844_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|224055
NZ_CP047147.1|WP_008404117.1|4284966_4285230_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_003950021.1|4266745_4267129_+|cold-shock-protein	unknown	unknown	gnl|CDD|224197
NZ_CP047147.1|WP_008406155.1|4271384_4272245_+|DUF3027-domain-containing-protein	unknown	unknown	gnl|CDD|378605
NZ_CP047147.1|WP_008404125.1|4279250_4280111_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_033240380.1|4280216_4282655_-|HAD-IC-family-P-type-ATPase	unknown	unknown	gnl|CDD|319795
NZ_CP047147.1|WP_107060929.1|4269506_4270973_-|MFS-transporter	unknown	unknown	gnl|CDD|340863
NZ_CP047147.1|WP_003950032.1|4283447_4284893_+|NCS2-family-permease	unknown	unknown	gnl|CDD|225161
NZ_CP047147.1|WP_008404115.1|4285969_4287316_+|MFS-transporter	unknown	unknown	gnl|CDD|340863
NZ_CP047147.1|WP_003950020.1|4266352_4266604_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_008415563.1|4268952_4269477_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_003950034.1|4285428_4285866_+|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NZ_CP047147.1|WP_159312895.1|4273328_4276562_+|molecular-chaperone-Hsp90	unknown	unknown	unknown
NZ_CP047147.1|WP_159313941.1|4265333_4266044_-|DNA-binding-response-regulator	unknown	unknown	gnl|CDD|225107
NZ_CP047147.1|WP_159313942.1|4268206_4268932_-|futalosine-hydrolase	unknown	unknown	gnl|CDD|350166
NZ_CP047147.1|WP_159312897.1|4287394_4287985_+|RNA-2',3'-cyclic-phosphodiesterase	unknown	unknown	gnl|CDD|274058
NZ_CP047147.1|WP_003950022.1|4267245_4268139_-|1,4-dihydroxy-6-naphthoate-synthase	unknown	unknown	gnl|CDD|270353
NZ_CP047147.1|WP_010643321.1|4282823_4283090_-|DUF2530-domain-containing-protein	unknown	unknown	gnl|CDD|378488
NZ_CP047147.1|WP_003950037.1|4288204_4289200_-|aldo/keto-reductase	unknown	unknown	gnl|CDD|381313
NZ_CP047147.1|WP_159312896.1|4277647_4278907_-|cytochrome-P450	unknown	unknown	gnl|CDD|225035

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_159312894.1|4262912_4264844_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	3.31446e-44
NZ_CP047147.1|WP_003950034.1|4285428_4285866_+|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.04287e-20
NZ_CP047147.1|WP_003950021.1|4266745_4267129_+|cold-shock-protein	gnl|CDD|224197	COG1278, CspC, Cold shock proteins [Transcription].	5.07314e-27
NZ_CP047147.1|WP_008406155.1|4271384_4272245_+|DUF3027-domain-containing-protein	gnl|CDD|378605	pfam11228, DUF3027, Protein of unknown function (DUF3027). This family of proteins with unknown function appears to be restricted to Actinobacteria.	2.60749e-109
NZ_CP047147.1|WP_003950032.1|4283447_4284893_+|NCS2-family-permease	gnl|CDD|225161	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism].	1.89915e-107
NZ_CP047147.1|WP_159312896.1|4277647_4278907_-|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	1.47198e-73
NZ_CP047147.1|WP_008404115.1|4285969_4287316_+|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.19265e-82
NZ_CP047147.1|WP_010643321.1|4282823_4283090_-|DUF2530-domain-containing-protein	gnl|CDD|378488	pfam10745, DUF2530, Protein of unknown function (DUF2530). This family of proteins with unknown function appears to be restricted to mycobacteria.	0.00969272
NZ_CP047147.1|WP_033240380.1|4280216_4282655_-|HAD-IC-family-P-type-ATPase	gnl|CDD|319795	cd02609, P-type_ATPase, uncharacterized subfamily of P-type ATPase transporter, similar to uncharacterized Streptococcus pneumoniae exported protein 7, Exp7. This subfamily contains P-type ATPase transporters of unknown function, similar to Streptococcus pneumoniae Exp7. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids. They are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle. A general characteristic of P-type ATPases is a bundle of transmembrane helices which make up the transport path, and three domains on the cytoplasmic side of the membrane. Members include pumps that transport various light metal ions, such as H(+), Na(+), K(+), Ca(2+), and Mg(2+), pumps that transport indispensable trace elements, such as Zn(2+) and Cu(2+), pumps that remove toxic heavy metal ions, such as Cd(2+), and pumps such as aminophospholipid translocases which transport phosphatidylserine and phosphatidylethanolamine.	0
NZ_CP047147.1|WP_107060929.1|4269506_4270973_-|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.948e-26
NZ_CP047147.1|WP_159313941.1|4265333_4266044_-|DNA-binding-response-regulator	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	2.32283e-25
NZ_CP047147.1|WP_159313942.1|4268206_4268932_-|futalosine-hydrolase	gnl|CDD|350166	cd17766, futalosine_nucleosidase_MqnB, futalosine nucleosidase which catalyzes the hydrolysis of futalosine to dehypoxanthinylfutalosine and a hypoxanthine base; similar to Thermus thermophiles MqnB. Futalosine nucleosidase (MqnB, EC 3.2.2.26, also known as futalosine hydrolase) functions in an alternative menaquinone biosynthetic pathway (the futalosine pathway) which operates in some bacteria, including Streptomyces coelicolor and Thermus thermophiles. This domain model belongs to the PNP_UDP_1 superfamily which includes members which accept a range of purine nucleosides as well as the pyrimidine nucleoside uridine. PNP_UDP_1 includes phosphorolytic nucleosidases, such as purine nucleoside phosphorylase (PNPs, EC. 2.4.2.1), uridine phosphorylase (UP, EC 2.4.2.3), and 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP, EC 2.4.2.28), and hydrolytic nucleosidases, such as AMP nucleosidase (AMN, EC 3.2.2.4), and 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase (MTAN, EC 3.2.2.16). Superfamily members have different physiologically relevant quaternary structures: hexameric such as the trimer-of-dimers arrangement of Shewanella oneidensis MR-1 UP, homotrimeric such as human PNP and Escherichia coli PNPII (XapA), homohexomeric (with some evidence for co-existence of a trimeric form) such as E. coli PNPI (DeoD), or homodimeric such as human and Trypanosoma brucei UP. The PNP_UDP_2 (nucleoside phosphorylase-II family) is a different structural family.	8.02478e-67
NZ_CP047147.1|WP_159312897.1|4287394_4287985_+|RNA-2',3'-cyclic-phosphodiesterase	gnl|CDD|274058	TIGR02258, UPF0097_protein_AF_2157, 2'-5' RNA ligase. This protein family consists of bacterial and archaeal proteins with two tandem copies of Pfam domain pfam02834. Members for which activity has been measured perform a reversible, ATP-independent 2'-5'-ligation of what is presumably a non-phyiological substrate: half-tRNA splice intermediates from an intron-containing yeast tRNA. The physiological substrate(s) in prokaryotes may include small 2'-5'-link-containing oligonucleotides, perhaps with regulatory or biosynthetic roles. [Transcription, RNA processing].	2.31308e-36
NZ_CP047147.1|WP_003950037.1|4288204_4289200_-|aldo/keto-reductase	gnl|CDD|381313	cd19087, AKR_AKR12A1_B1_C1, AKR12A, AKR12B, AKR12C families of aldo-keto reductase (AKR). Streptomyces fradiae TylCII, Saccharopolyspora erythraea EryBII, and Streptomyces avermitilis aveBVIII are founding members of aldo-keto reductase family 12 member A1 (AKR12A1), B1 (AKR12B1), and C1(AKR12C1), respectively. TylCII acts as a NDP-hexose 2,3-enoyl reductase. EryBII is a mycarose/desosamine reductase involved in L-mycarose and D-desosamine production. aveBVIII functions as a dTDP-4-keto-6-deoxy-L-hexose-2,3-reductase.	2.50541e-167
NZ_CP047147.1|WP_003950022.1|4267245_4268139_-|1,4-dihydroxy-6-naphthoate-synthase	gnl|CDD|270353	cd13635, PBP2_Ttha1568_Mqnd, A menaquinone biosynthetic enzyme exhibits the type 2 periplasmic-binding protein fold. This group includes Ttha1568 (MqnD) from Thermus thermophilies HB8, an enzyme within an alternative menaquinone biosynthetic pathway that catalyzes the conversion of cyclic de-hypoxanthine futalosine to 1,4-dihydroxy-6-naphthoate. Menaquinone (MK; vitamin K) is an essential lipid-soluble carrier that shuttles electrons between membrane-bound protein complexes in the electron transport chain. Ttha1568 has significant structural homology with the members of type 2 periplasmic-binding fold protein superfamily. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	2.21409e-142

Protein sequences

>NZ_CP047147.1|WP_159312895.1|4273328_4276562_+|molecular-chaperone-Hsp90
MTHPTPAQEGKDPFGTARRRRTVLDSWAASPARFREDANAEEDLALGGYRDRLIVELAQNAADAASRAGTDGRLRLTLHESAGTHVLAAANTGAPLDATGVESLSTLRASAKRPATGTATGAAPGAGPSVGRFGVGFAAVLAVSDEPAVLSRTGGVRWDLAQAREAAREVARHSPGLGDELIRRDDHVPLLRLPFPAEGTPPEGYDTVVVLPLRDAAAQDLAERLLAAVDDALLLALPGLTEIVVETPESTRALRRRDEEPYVVIEESTGGSGATGSGATGAPAETRRWRTATSGGPLDAPLLADRPVEERLRPYWSVVWAVPVDAEGAPVRPATAPVVHAPTPSDEPLGVPALLIASFPLDTARRHVAPGPLTDFLVGRAAEAYAGLLGAWRPVGPAAVGLVPGPLGLAAVDGAVRAAVLDLLPRTAFLPPALPPAGPDEEPDTDVPLLRADRPEALRPIEAELVEGAGEATVRVLAEVLPTLLPAGLERRAELRTLGVGRLSLGEAIDRLAGVERSPAWWYRLYDSLAGVDPDRLQGLPVPLAAGSTAGSPRQVLLPGPAEDGPRPAALARLGLKVAHPEAAHPLLEKLGALPATPRAVLRTPQVRAAVAESLEGDGYALRDDAPDAEELAELVLTLARDAELAPGDEPWLGALALPDEDGELSPAGELVLPGGEFASVMREGELAAVDEEWAGRWGEQPLAACGVLARFTLVRATDVVLDPDELEPRDSDFAEPDDVGLLDAVDVWCEDVLDQLPDGPVPPVATEITAVRDLDLVDDDRWPEALALLSRPPLRDALTQPVRVLLPDGTTESVRPYTAWWLRGHPVLDGRRPAGLRAASGDALLAGLYDEVDAAGFDDALVLRALGVRTTAAALLDEPGGAAELLDRLADPDREVSARQLHALYGLLAELDPEEVTLPDELRAVADGVVTVVDARDALVADAPDLLPFAAGRPLLPVAPALAARLAELLQVGRLSEAVRVTPAGEGVEYPVPEAVRELLGDGVPASYREHDELLADGVELDWHLTASGVLHAATLEGVAAGLAWGAGQWPRRFEVAALLEDPSRRAELSRDRWFD
>NZ_CP047147.1|WP_008406155.1|4271384_4272245_+|DUF3027-domain-containing-protein
MSAATTRSRTPDRLCAEAVDLARSVAEETAAPGVVGEHLAVTADGDRVATHYFACHDPGYRGWRWAVTVARASRAKYVTVDESVLLPGPDALLAPEWVPWSERLRPGDLGPGDLLPTEADDLRLEPGWIADEEPPPNSAVSADMAELVEAEDASLSAGPPADLPLAPERGSVASVAEELGLRRSRVLSRYGLLDAAERWEAQFGAESAMAQAAPAPCVSCGFLLPLAGSLRQAFGICANAYSPADGHVVSLAYGCGGHSEAAVMPTPPRPPDPALDETRLDPLPLD
>NZ_CP047147.1|WP_107060929.1|4269506_4270973_-|MFS-transporter
MRRAARVVGRALRTPVTGPARGIRKVTHAQGAGESGLGRLIELHGVNGAGDVMITVALASTVFFSVPTDEARGRVALYLAVTMLPFTLLAPVVGPLLDRLPHGRRAAMAGSMLARAVLALVLSGAVATGSLEMYPAALGVLVASKAYGVVRSAVVPRLLPQGFSLVKANSRVTLGGLLATGVAAPVGAGLQMIGPGWPLYGACLLFLGGAFLSFRLPPKVDSARGERRALLAADEQHLAAAVDARWDPVTTDDKTDDKTDSTDNKEEEKDRDGERGDGERGKGKERRRKGPGLRTVGPAVTHALAANACVRCQSGFLIFFLAFLLREHPLTGQSAAVSLAVVGVAAGAGNALGTAVGAWLRARAPEVIIVTVVGALVAVAVSAAVFFGAAVVAVLGAVAGFTQALAKLSLDALIQRDVPELVRTSAFARSETLLQMAWVVGGAIGIALPLRGPLGLSVGALIVALGWLTTVRALLASARRGASHPRVA
>NZ_CP047147.1|WP_008415563.1|4268952_4269477_-|hypothetical-protein
MTSLPRGGAARQFSPATRRGFAVLGAVSAGLLVLSACDKPTAVATVTIGSDSVNSEATCWNGGSKIDEKKLQQCLQDKGEGDSGDGAEVKTVKVDTEADVHIGVDPKIADKGWTILMNGQPLTDASNKTFRTIPGSVFFNQQYGASGDSTVLSILENDGSSATGLWSFKLEKES
>NZ_CP047147.1|WP_159313942.1|4268206_4268932_-|futalosine-hydrolase
MRLLVATAVPPERDAVARAFGAPDTPEETALPGAVLLRTPGADVLAAGVGPAAAASATSAALTAARLAGNPYDLVVSAGIGGGFAERAPVGAVVVADRIVAADLGAETPDGFVPVTGLGFGTDVHVPPAALVEAAREAGLVPGAVLTVSTVTGSADRAAELLARHPSAVAEAMEGFGVAEAAAAHGVPVLEIRAISNAIGPRDRDAWRIPAALTALTSAFVRLAPAEAGSPFALARARLVP
>NZ_CP047147.1|WP_003950022.1|4267245_4268139_-|1,4-dihydroxy-6-naphthoate-synthase
MSESGTGGVQGTADEAGRLSIAYSPCPNDTFVFDAVAHGRVPGAPALDVTFADIDLTNGMAERGAYDVLKVSYAALPWLLDEYALLPCGGALGRGCGPLVLTREASLPGALAGRTVAVPSERSTAYLLFRLWAADQVPGGVGEIVVMPFHEIMPAVRDGKVDAGLVIHEARFTYQNYGLHKLADMGEHWEATTGLPIPLGAIIARRSLGAERLTALAQALRTSVRMAWDDPAASRPYVLAHAQEMDADVADQHIGLYVNEFTADLGEDGYAAVRGLLTRAAAEGLVPPLAPDALRFP
>NZ_CP047147.1|WP_003950021.1|4266745_4267129_+|cold-shock-protein
MPTGKVKWFNSEKGFGFLSRDDGGDVFVHSSVLPAGVEALKPGQRVEFGVVAGQRGDQALSVVLLDPAPSVAAAQRRKPDELASIVQDLTTVLENVSRSLERGRYPDRASGAKVAGMLRAVADQLDV
>NZ_CP047147.1|WP_003950020.1|4266352_4266604_-|hypothetical-protein
MSDTTQQTPAPGDRLVKTGGIVFIIGALATLVTVAPLFLGSDPFPTAAYLVSMLMGVGFLIAGAGLVRQIAAQRRETRAAVEG
>NZ_CP047147.1|WP_159313941.1|4265333_4266044_-|DNA-binding-response-regulator
MIHSSGVLRSALVALLERERFQVTSASGFSRASSGATGAPGTPGAPATVTVVDGSCPVGAAHLERRSLQGSAKEPTHATPALAAARPGLGLAGAGAERAGIGLAGASRGRAALVVLAGAEHPGVLRLAYTAGALGLVDRDGPANHLATAIRLAAGGGRYVDDGLAMSLLRAMDMPLSPREVRVLSRAAQGDSVAEIARGLCLSHGTVRNYIASATRKVGARNRVDAIRISRAAGWV
>NZ_CP047147.1|WP_159312894.1|4262912_4264844_+|ATP-binding-cassette-domain-containing-protein
MTRPRHTDGAPSPLLRPALTFARRRKGPLGALGAWSLLESARTFLTGYAVARALDDGFLAGDVRTGLVWLLALGAAAFAGGFADAGVFRALGGVIEPLRDSLVRRVVRVTLTRAVASPTPADTARVSRLTAQTEIARDAAGGVLLTVRSFLFTSAGAFTGLAALSLRLLPLVLIPLAAGLALFAATLRPMAARQRDLLDADEHLAAFAGRTDHAARDIAATGAAPLVTAEAAPLITAEATAASALARWAAVRVTALGLAAHLPVATLLLAAPTLLSTGLTPGELLAALTYVTTALLPAVNALLTALGAAGSRLLVVLHRLLGEEADAADVREEQPHTLRVDDGPRAPGAWSKGKADDEVPAIPAPSLPPEPVHGPEPFRAEPSPPGPRPTRGPRPTRPAPPAATLRGVTFAYGPDAAPVLDHLDLTVEPGEHLLVVGPSGAGKSTLLALLAGTAHPRHGQIHLAGHTARHARTLGTAARVLVPQEPYIFEAPLHDNLTYLAPDAPAPRITEAIHTFTLASLAADPARPLRPDHLTPSERRRIALARAWLTPTPLLLLDEPTAHLDAGARAATELAFASHPATVITVSHHFPAPEPGQRVLLLDGATPYLGTHASLLRESALYGELAAGLGEPSAAGSRGTALT
>NZ_CP047147.1|WP_159312896.1|4277647_4278907_-|cytochrome-P450
MPSSAPPEQEPLVLDPTGADPHAEHRALHARGPATRVDVLGVPAWSVSDPALLRALLTSPDVSKDGRAHWPAFAETVQSWPLALWIAVRNMFTSYGADHRRLRRIIAPAFSARRVAAVRPVVERITAGLLDDLAALPPDAPVDLREKLAYPLPVAVIGHLMGVPEERYAHFRAVVDGVFDTTLGREEAAANTDALYVVLDELIATRRAEPGDDLTSLLLATPDEEGAEPALSHEELRDTLLLVISAGYETTVNVIDQAVHALLTVDGQLDLVRSGQVGWGDVVEETLRHESAVKHLPLRYAVRDIPLPDGRTIARGEAILASYAAANRHPGWHDDADVFDAGRLSKEHLAFGHGVHFCVGAPLARLEVEVCLRLLFARFPGLALDLPAEGLPPFPSLISNGHRNLPVWLHGGALGEGPG
>NZ_CP047147.1|WP_008404125.1|4279250_4280111_+|hypothetical-protein
MRIRATVAVVSGALALSALTGAAAQAAPGPDRERIQVPTAESVFGKQATAKGKGFKAAAVPKISKVTVNGGKDIVLGTTKAKTFSVSITASHASNIGDAYAYFWHGSTYETADGVFIPNEEYASCKASSATTSTCKLTFTVDPQWELINDLAGSWNVGVGALAADDSDFAWNDKHSKTRVQRYSKLVVNATPEPVKKGKTLTVNGTLSRANWDTWKYAGYTQQSVKLQFKKKGAASYTTVKTVKSGSKGALKTTVKAASDGYWRWSFAGTSTTPAINSTADFVDVK
>NZ_CP047147.1|WP_033240380.1|4280216_4282655_-|HAD-IC-family-P-type-ATPase
MTQRGQVDTGGSDSGNSRIDTGAEPDAAPPAVPPEPGLTSAEVAEAVARGEVNDVPVRSSRSLAEIARANIFTRFNAIIGVLWVIMLFVAPIQDSLFGFVIVANTGIGIFQEWRAKRTLDGLAVIGEAKPTVRRDGRPGEISTSEIVLGDLIEIGPGDKIVVDGEVREADGLEVDESLLTGEADPVVKRPGDEVMSGSFVTAGGGAFRATKVGREAYAAQLAEEASRFTLVHSELRSGISTILKYVTWMMVPTAIGLVVSQLVVRDNDFKNAVARTVGGIVPMVPEGLVLLTSVAFAIGVIRLGRKQCLVQELPAIEGLARVDTVCLDKTGTLTEGGMDVQAIRPLGGADEAYVRRVLGALGAGDPRPNASLQAVIDACPAPEGWRTTGTLPFSSARKYSGASLDEGDATHRTWLLGAPDVLLRPGAEALAETDALNERGLRVLLLSRAAGGLDGPDPGAGAEPTALVVLEQRLRPDAADTLRYFEDQHVAAKVISGDNAVSVGAVAGKLGLPGAERTYDARKLPKEPEALADTLDENTVFGRVTPQQKRDMVGALQAHGHTVAMTGDGVNDVLALKDADIGVSMGSGSEATRAVAQIVLLNNSFSTLPSVVAEGRRVIGNITRVATLFLVKTVYSVLLAILVVLSQTEYPFLPRHLTLLSTLTIGVPAFFLALAPNKERAQPHFVKRVMRYAIPGGVIAALATFTTYMTARAYYTGPDSLPAETSAATLTLFLVSLWVLAIIARPYTWWRVGLVATMAGAFLVVLAVPWLQDFFALRLVGSVMPWAAVGIAVIAAALIEVVWRLVDRRLPV
>NZ_CP047147.1|WP_010643321.1|4282823_4283090_-|DUF2530-domain-containing-protein
MKKWTPRHEAPEPLEGPVVATITGGTILWFVLFLAQLPFYGWYADHGHTWWIWTCLAGAGLGCLGVWYVRRREAALKRAAAAAPQPGS
>NZ_CP047147.1|WP_003950032.1|4283447_4284893_+|NCS2-family-permease
MPTSAPAQDATSEQPNPPSGALDRYFKITERGSTLSREVRGGFATFFAMAYIIVLNPIILGSAKDMYGHQLDNGQLVTATVLTAALTTLLMGVIGNVPVALAAGLGVNTVVALQLAPRMSWPDAMGMVVLAGFVVMLLVATGLRERVMSAVPLGLRKGIAIGIGLFIMLIGLVDAGFVSRIPDAAQTTVPLQLGADGHLNGWTVLVFVLGVLLTLALMVRKVPGAILISIVAMTVLALIINAVADIPSWGLTTPEWPGNPVATPDFGLIGQVSLFGGFAKVGLLTGILFVFTVLLSCFFDAMGTIMAVGDEAELTDAQGNMPGINKVLFVDGIAVAAGGASSSSATTCFVESTAGVGEGARTGFANIVTGGLFAIGLFLTPVVTMVPSQAATPALVAVGFLILSGSIGAIDWTDFTIAIPAFITFMMMPFTYSITNGIGMGFISFCVLRLAAGRGRSVPAAMYVVSGVFAFYYLMPALGLT
>NZ_CP047147.1|WP_008404117.1|4284966_4285230_-|hypothetical-protein
MDTHVLSLRMDSELFERLRGHAARRGMSVQDYVVRTMIRDDFDQRFQTAVEETEKFYGDEDGGAPGAGEVAEEPARDGAVNGAARPT
>NZ_CP047147.1|WP_003950034.1|4285428_4285866_+|MarR-family-transcriptional-regulator
MPDLTHGEDADAVNALRSSVMRLSRRLKHQRVDESLSPTEMSVLGTLARCGTATPGELARKEHVQPPSMTRIVALLEAKGLVRLEPHPEDRRQKVVTQTEEAEAMLEESRSKRNAWLASLAAELDEEEWAKVRAAAPVLEKLAHL
>NZ_CP047147.1|WP_008404115.1|4285969_4287316_+|MFS-transporter
MSTGPGADSAPAPAAHDSTPPAPKQSMFSSLKIHNYRLFFTGQVISNTGTWMQRIAQDWLVLTLTGSSAAVGVTTALQFLPMLLFGLYGGVLVDRLPKRPLLLFTQSAMGLTGLALAALTLTGHVQVWHVYVTAFVLGLVTVVDNPARQTFVSEMVGPRQLANAVSLNSANFQSARLVGPAVAAVLISAVGSGYAFLINGLSFAAPIAGLLMMRMGDLHKAPRTPRGKGQLREGLRYVAGRPDLIWPIVLVGFIGTFGFNFPIWLSAFADKVFDGGPGMYGTLNTLIAAGSLAGALLAARRGAGRLRLLVAAAAAFGVLEIVAAFAPSVWIFAVLMVLTGMFGLTVNVTANSYVQMATEPQMRGRVMALFMMVFTGGTPLGAPLLGWITDEYGARTGFAVGGAISLLAALAVGLILARVGGLKVKVDLRRGRKHIRFVPDEKRLAPAA
>NZ_CP047147.1|WP_159312897.1|4287394_4287985_+|RNA-2',3'-cyclic-phosphodiesterase
MASPAPRPRLFVAVVPPDAVLAELRRATAALDALPGAGRLRPTEAGGRHVTLAFLGACDPGRLDGLAARLARAAHRTAPFPLALRGAGHFGDRVLWARPDGDLDALARLAERVRAAATRAGLPPDAEHAFRPHLTLARVRPGPPLRLAPFAEALAQLAAGPWQADEVRLVRSVPPPGGVPGARPTYATEGRWPLGG
>NZ_CP047147.1|WP_003950037.1|4288204_4289200_-|aldo/keto-reductase
MKYTQLGRTGLKVSRLVLGTMNFGPKTGEAESHALMDTALDDGINFFDTANVYGWGENKGRTEEILGTWFAQGGDRRDKVVLATKVYGNMGADGSAWPNHDRLSALNIRRAVDASLRRLQTDHIDLYQFHHVDRRTPFDEIWQAMDTLVQQGKILYAGSSNFPGYKIAQANEAAARRGSLGLVSEQCLYNLAERRAEMEVIPAAEEYGLGVIAWSPLHGGLLGGAIRKEREGGGSRTNDGRSGDALANSTIRAQVQAYEDLLEKHGLEPGEVALAWLLTRPGLTGPIVGPRTDEQLASAVRAVELELPQELLTALDEIFPGPGPSPEAFAW

Crispr_ID: NZ_CP047147_26

• CRISPR_ID: NZ_CP047147_26
• CRISPR_location: 4649222-4649323
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP047147_26

Consensus_repeat	Method
CGGCGGCGGCTTCGGCGGCATCCT	CRISPRCasFinder

spacers of NZ_CP047147_26

>26.1|4649246|54|NZ_CP047147|CRISPRCasFinder
CGCCGGGGCGCGGCTGCGCCGGCAGGGCGTGGAGCGCGTCCGCATCGTGGAGAC

CRISPR arrays and Neighbor proteins around NZ_CP047147_26

CRISPR arrays

The CRISPR arrays of NZ_CP047147_26

>merge|NZ_CP047147|26|4649222-4649323|CRISPRCasFinder
CGGCGGCGGCTTCGGCGGCATCCTCGCCGGGGCGCGGCTGCGCCGGCAGGGCGTGGAGCGCGTCCGCATCGTGGAGACCGGCGGCGGCTTCGGCGGCACCTG

>NZ_CP047147|26|21|4649222-4649323|CRISPRCasFinder
CGGCGGCGGCTTCGGCGGCATCCT	CGCCGGGGCGCGGCTGCGCCGGCAGGGCGTGGAGCGCGTCCGCATCGTGGAGAC
CGGCGGCGGCTTCGGCGGCACCTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_159313000.1|4660030_4661263_+|hypothetical-protein	unknown	unknown	gnl|CDD|182079
NZ_CP047147.1|WP_159313951.1|4654163_4654631_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159312995.1|4642942_4643491_-|GtrA-family-protein	unknown	unknown	gnl|CDD|377229
NZ_CP047147.1|WP_008417638.1|4654681_4654915_-|DUF397-domain-containing-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_003950402.1|4652938_4654096_+|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173847
NZ_CP047147.1|WP_159312999.1|4657380_4659021_+|catalase	unknown	unknown	gnl|CDD|163710
NZ_CP047147.1|WP_008417648.1|4647187_4647739_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|366102
NZ_CP047147.1|WP_003950396.1|4646668_4647025_-|VOC-family-protein	unknown	unknown	gnl|CDD|380093
NZ_CP047147.1|WP_030307946.1|4638939_4640430_-|MFS-transporter	unknown	unknown	gnl|CDD|273342
NZ_CP047147.1|WP_159312997.1|4655610_4656459_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|238045
NZ_CP047147.1|WP_003950390.1|4640958_4641636_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NZ_CP047147.1|WP_044474806.1|4644866_4645367_+|5-(carboxyamino)imidazole-ribonucleotide-mutase	unknown	unknown	gnl|CDD|376377
NZ_CP047147.1|WP_159312998.1|4656540_4657065_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_071337271.1|4650847_4651357_+|CGNR-zinc-finger-domain-containing-protein	unknown	unknown	gnl|CDD|378696
NZ_CP047147.1|WP_031178248.1|4647752_4648775_-|SMP-30/gluconolactonase/LRE-family-protein	unknown	unknown	gnl|CDD|225921
NZ_CP047147.1|WP_010642901.1|4651382_4652726_-|UDP-glucose/GDP-mannose-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|223936
NZ_CP047147.1|WP_075986466.1|4643688_4644828_+|5-(carboxyamino)imidazole-ribonucleotide-synthase	unknown	unknown	gnl|CDD|235674
NZ_CP047147.1|WP_008417627.1|4659094_4659847_-|tellurium-resistance-protein-TerA	unknown	unknown	gnl|CDD|226595
NZ_CP047147.1|WP_003950391.1|4641688_4642927_+|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NZ_CP047147.1|WP_003950395.1|4645377_4646595_+|membrane-dipeptidase	unknown	unknown	gnl|CDD|366534

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_159312995.1|4642942_4643491_-|GtrA-family-protein	gnl|CDD|377229	pfam04138, GtrA, GtrA-like protein. Members of this family are predicted to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharides. The GtrA family are a subset of this family. GtrA is predicted to be an integral membrane protein with 4 transmembrane spans. It is involved is in O antigen modification by Shigella flexneri bacteriophage X (SfX), but does not determine the specificity of glucosylation. Its function remains unknown, but it may play a role in translocation of undecaprenyl phosphate linked glucose (UndP-Glc) across the cytoplasmic membrane. Another member of this family is a DTDP-glucose-4-keto-6-deoxy-D-glucose reductase, which catalyzes the conversion of dTDP-4-keto-6-deoxy-D-glucose to dTDP-D-fucose, which is involved in the biosynthesis of the serotype-specific polysaccharide antigen of Actinobacillus actinomycetemcomitans Y4 (serotype b). This family also includes the teichoic acid glycosylation protein, GtcA, which is a serotype-specific protein in some Listeria innocua and monocytogenes strains. Its exact function is not known, but it is essential for decoration of cell wall teichoic acids with glucose and galactose.	1.2478e-24
NZ_CP047147.1|WP_159313000.1|4660030_4661263_+|hypothetical-protein	gnl|CDD|182079	PRK09793, PRK09793, methyl-accepting chemotaxis protein IV.	0.000928238
NZ_CP047147.1|WP_003950402.1|4652938_4654096_+|acyl-CoA-dehydrogenase	gnl|CDD|173847	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases. Short chain acyl-CoA dehydrogenase (SCAD). SCAD is a mitochondrial beta-oxidation enzyme. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of SCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. This subgroup also contains the eukaryotic short/branched chain acyl-CoA dehydrogenase(SBCAD), the bacterial butyryl-CoA dehydorgenase(BCAD) and 2-methylbutyryl-CoA dehydrogenase, which is involved in isoleucine catabolism. These enzymes are homotetramers.	0
NZ_CP047147.1|WP_159312999.1|4657380_4659021_+|catalase	gnl|CDD|163710	cd08154, catalase_clade_1, Clade 1 of the heme-binding enzyme catalase. Catalase is a ubiquitous enzyme found in both prokaryotes and eukaryotes, which is involved in the protection of cells from the toxic effects of peroxides. It catalyzes the conversion of hydrogen peroxide to water and molecular oxygen. Catalases also utilize hydrogen peroxide to oxidize various substrates such as alcohol or phenols. Clade 1 catalases are found in bacteria, algae, and plants; they have a relatively small subunit size of 55 to 69 kDa, and bind a protoheme IX (heme b) group buried deep inside the structure. They appear to form tetramers. In eukaryotic cells, catalases are located in peroxisomes.	0
NZ_CP047147.1|WP_008417648.1|4647187_4647739_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	1.82391e-08
NZ_CP047147.1|WP_003950396.1|4646668_4647025_-|VOC-family-protein	gnl|CDD|380093	pfam18029, Glyoxalase_6, Glyoxalase-like domain. This entry comprises a diverse set of domains related to the Glyoxalase domain. The exact specificity of these proteins is uncertain.	2.6577e-23
NZ_CP047147.1|WP_030307946.1|4638939_4640430_-|MFS-transporter	gnl|CDD|273342	TIGR00924, putative_Di/Tri_peptide_transporter, amino acid/peptide transporter (Peptide:H+ symporter), bacterial. The model describes proton-dependent oligopeptide transporters in bacteria. This model is restricted in its range in recognizing bacterial proton-dependent oligopeptide transporters, although they are found in yeast, plants and animals. They function by proton symport in a 1:1 stoichiometry, which is variable in different species. All of them are predicted to contain 12 transmembrane domains, for which limited experimental evidence exists. [Transport and binding proteins, Amino acids, peptides and amines].	0
NZ_CP047147.1|WP_159312997.1|4655610_4656459_+|helix-turn-helix-domain-containing-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.70501e-08
NZ_CP047147.1|WP_003950390.1|4640958_4641636_+|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	9.19407e-84
NZ_CP047147.1|WP_044474806.1|4644866_4645367_+|5-(carboxyamino)imidazole-ribonucleotide-mutase	gnl|CDD|376377	pfam00731, AIRC, AIR carboxylase. Members of this family catalyze the decarboxylation of 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR). This family catalyze the sixth step of de novo purine biosynthesis. Some members of this family contain two copies of this domain.	9.60722e-86
NZ_CP047147.1|WP_071337271.1|4650847_4651357_+|CGNR-zinc-finger-domain-containing-protein	gnl|CDD|378696	pfam11706, zf-CGNR, CGNR zinc finger. This family consists of a C-terminal zinc finger domain. It seems likely to be DNA-binding given the conservation of many positively charged residues. The domain is named after a highly conserved motif found in many members of the family.	3.79851e-18
NZ_CP047147.1|WP_031178248.1|4647752_4648775_-|SMP-30/gluconolactonase/LRE-family-protein	gnl|CDD|225921	COG3386, COG3386, Gluconolactonase [Carbohydrate transport and metabolism].	5.10136e-25
NZ_CP047147.1|WP_010642901.1|4651382_4652726_-|UDP-glucose/GDP-mannose-dehydrogenase-family-protein	gnl|CDD|223936	COG1004, Ugd, Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane].	0
NZ_CP047147.1|WP_075986466.1|4643688_4644828_+|5-(carboxyamino)imidazole-ribonucleotide-synthase	gnl|CDD|235674	PRK06019, PRK06019, phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed.	5.24824e-179
NZ_CP047147.1|WP_008417627.1|4659094_4659847_-|tellurium-resistance-protein-TerA	gnl|CDD|226595	COG4110, COG4110, Uncharacterized protein involved in stress response [General function prediction only].	8.66102e-36
NZ_CP047147.1|WP_003950391.1|4641688_4642927_+|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	3.86237e-31
NZ_CP047147.1|WP_003950395.1|4645377_4646595_+|membrane-dipeptidase	gnl|CDD|366534	pfam01244, Peptidase_M19, Membrane dipeptidase (Peptidase family M19).	3.01559e-140

Protein sequences

>NZ_CP047147.1|WP_031178248.1|4647752_4648775_-|SMP-30/gluconolactonase/LRE-family-protein
MRRTTLRSLAGIAALTTLALTGCGTQQGLADDSPAAAGPAERTITAKRLARLTQPHEQTGMTLLEGPLLDAKGRLLVVDVTAPAGEPKMIRVDVRTGKGTPFHTDERGAYTSAQYSPHDGRIYLTDYAHGEIVSLAPGGGDRQVFFTGKVDGAAMHPDDLAFDRSGNLYVSDSRGLSEGTAEGRVVRISRDGKKATVLADQLAATNGISFDAEYRGLWFSELTENRISYLRLDDQGEVTSRHTAIRVDGGLAQTDSIAVDADGNLYQGLHGRAAMAVYDRHGARLATVEVPARHRGLESATNVAITPGGTRAYLTVSGPAGGYVYTFDALAEGIRQSNGG
>NZ_CP047147.1|WP_008417648.1|4647187_4647739_+|helix-turn-helix-transcriptional-regulator
MNQGPRAAARNRAALVAAAREVYAELGLDAPMAEIARRAGVGQGSLYRHFPDRDAVVATVLEENVLQVEQAAAADGATLADVLAVLTWHLVESAAFIGLLRAEYATVRREELGRAGELGERVERALRGELRDRGPLPAGSLMLAVAMVSGAVTGPTREDRERRALEAWALLGVEVGPVRPFPG
>NZ_CP047147.1|WP_003950396.1|4646668_4647025_-|VOC-family-protein
MPIATLDVVVLDTPAPLALATFYQAILGGTVEQPADYWVELHGPGVKLAFQEAPDMVPPTWPSPDNSQQFHLDLNVPDLEAAESQVLALGARPLDTRPDRSFRVYADPSGHPFCLCRQ
>NZ_CP047147.1|WP_003950395.1|4645377_4646595_+|membrane-dipeptidase
MTSTPTGPVPNAELLPTALEFLAEHPVVDGHNDLPWALREQVRYDLDRRDIAEDQSAHLHTDIARLRAGGVGAQFWSVYVRSDLGGDEAVSATLEQIDCVDQLLARYPADLAPAETADAMEKARTEGRIASLKGAEGGHSINNSLATLRALHALGVRYMTLTHNDNIAWADSATDTERLGGLSAFGREVVREMNRTGMLVDLSHVSAGTMRDALATSEAPVIFSHSSSRAVCDHPRNIPDDVLAQLPANGGVAMATFVPKFILPAAVEWTLRADENLRAHGHHHLDTGEEAMALHRAFEAAHPRPVATAATVADHLDHMREVAGVDHIGIGGDYDGTAFTPAGLEDVAGYPNLVAELLSRNWSTADLAKLTWGNAVRVLRDAEAVSRDLAARRGPSNATLEQLDG
>NZ_CP047147.1|WP_044474806.1|4644866_4645367_+|5-(carboxyamino)imidazole-ribonucleotide-mutase
MGSDSDWPVMEAAAQALDEFELPYEVDVVSAHRMPHEMIAYGEQAAGRGLKAVIAGAGGAAHLPGMLASVTPLPVIGVPVPLKYLDGMDSLLSIVQMPAGVPVATVSVGGARNAGLLAARILAAHDEELLGRMKEFQRELNEQATEKGKRLRAKTAGGPAGFGFGK
>NZ_CP047147.1|WP_075986466.1|4643688_4644828_+|5-(carboxyamino)imidazole-ribonucleotide-synthase
MTFPVVGMVGGGQLARMTHEAGIPLGIRFKLLSDTPQDSAAQVAGEVVVGDYRDLETLRAFARGCDVITFDHEHVPTEHLRALEADGIPVRPGPDALVHAQDKGVMRARLTEIGAPCPRHRIVADPADVAAFAEEGDGFPVVLKTVRGGYDGKGVWVVRSEADAAEPFRAGVPVLAEEMVPFRRELAANIVRSPHGQAVAYPVVESRQVDGVCDTVIAPAPGLSEELSGQAQELALRIADELGVVGHLAVELFETEDGRVLVNELAMRPHNSGHWTMDGAVTSQFANHVRAVLDLPLGDPRPRAPWTVMCNVLGGDYPDMYAAYLHCMARDPQLKIHMYGKDVKPGRKVGHVNTYGDDLDAVLERARHAAGYLRGTITE
>NZ_CP047147.1|WP_159312995.1|4642942_4643491_-|GtrA-family-protein
MSPAPGEPTPAATAPGASALRERVRRLVREVAKFGAVGGAGVLVNLAVFNLVRHLTELQVVRASVLATVVAIVFNYLGFRYFTYRDRDKGGRTREMSLFLAFSVVGLVIENGILYTGTYGLGFDGRLESNVLKFAGIGVATLFRFWSYRTWVFRAPAAVRAAKQATEPVREPVASGTSAGRS
>NZ_CP047147.1|WP_003950391.1|4641688_4642927_+|HAMP-domain-containing-histidine-kinase
MRRRLINSTLAVVLVVIAVFGGTLVIVETRTITNSAQESVESEALRLASIVDSRLISEERISAGLLQDQIAAKRYARIDIPGRAAIEIGERPDGDVIEARATGEEGESVLVQEPRAAVTGEVGRTLMIIGGVALLAVVAAVLLAVRQGNRLAAPLTDLAETAERLGSGDPRPRHKRYGVPELDRVADVLDGSAERIARMLTAERRLAADASHQLRTPLTALSMRLDEITLTEDLETVREEATIALAQVERLTDVVERLLTNARDPRTGSAVAFDLYEVVKQQLEEWRPAYRSEGRAIVCSGRRDLRAVATPGAVAQVLAALIENSLMHGGGTVALRTRVTGNQAVVEVADEGPGVPADLGARIFERTISGRNSTGIGLAVARDLAEADGGRLELLQPQPAVFGLFLSRAPED
>NZ_CP047147.1|WP_003950390.1|4640958_4641636_+|response-regulator-transcription-factor
MTRVLLAEDDASISEPLARALRREGYEVEVRQDGPTALDAGLRGGVDLVVLDLGLPGMDGLEVARRLRSDGHTVPILILTARADEVDTVVGLDAGADDYVTKPFRLAELLARVRALLRRGAAEPPQPTATHGVRIDVESHRAWMGDEELQLTAKEFDLLRVLVRDAGRVVTRDQLMREVWDTTWWSSTKTLDMHISWLRKKLGDDAANPRYIATVRGVGFRFEKS
>NZ_CP047147.1|WP_030307946.1|4638939_4640430_-|MFS-transporter
MASSLTKDAAGNPGSQKTFFGHPRGLATLFLTEMWERFSYYGMRALLPLYLIAPGGLALDAATATVIYSVYMATVYLLTLPGGWFGDRYWGPRKTVAIAASIVMLGHLTLALPGDAVFYVGLVLVAIGSGLLKANISTMVGHLYDGPNDPRRDGGFTVFYMGINIGAFAAPLVIGTVGENVGWHWGFGLAALGMGLGLLQFLLAGKTLSPRSSEVPKPLSSDERNNVIRKSLIWLLIAVVFYGIVGFSGSFTIKWATVPLTILGLVIPIMVLGRMKRDKELTGTEQSKLSAYVWFFIAAAVFWMIYDQGGSTLAIFADGKVDNQVFGWEFPVSWFQSVNPILVMALAPVFAWIWLYLNKKGKEPSTITKFAGGLTLVGISFFVFLLPLTASSDGSLVNPWWLVVIYFCQTVGELMLSPVGLSVTTKMAPAKYASQMMGVWFLAVTAGDSVTGLLSDSGVDLNRTGVVALEAALAVVGGFAIFMYRRKVKSLMGEIH
>NZ_CP047147.1|WP_071337271.1|4650847_4651357_+|CGNR-zinc-finger-domain-containing-protein
MARPSAPGPLVLVQDLVNTLDLETGADTLATEEGRAVFGLREADVAAARALREALRAACLAHAGHGAPAEVAALGTLLAQAPLVTTVDPADGSARLAPADPASLTARVAAAVARGSLDGSWQRLKACEDETCRWAYYDRSPAGRGRWCSMEVCGARAKMRAYRARRAGE
>NZ_CP047147.1|WP_010642901.1|4651382_4652726_-|UDP-glucose/GDP-mannose-dehydrogenase-family-protein
MALRITVIGTGYLGATHAAAMAELGFEVLGLDVVPEKIALLSQGRVPMYEPGLEELLGKHVAGIEGSSGRLRFTTSFEEVADFGDVHFVCVNTPQKPGEYACDMSYVESALASLAPHLKRPALVVGKSTVPVGSAERLAAELAAAAPVGEEAELAWNPEFLREGFAVDDTLHPDRIVVGVRGARAEELLREVYRTPVAEGSPFIVTDFPTAELVKTAANSFLATKISFINAMAEVCEAADGDVAKLAEALGHDDRIGAKFLRAGIGFGGGCLPKDIRAFMARAGELGADQALTFLREVDSVNMRRRGHMVELALEALGTTSFLGKRVAVLGATFKPDSDDVRDSPALNVAGQIHLQGGQVTVYDPKGMDNARRIFPTLGYADSALEAVRGADVVLHLTEWREFRELDPAELAAAVATPTLLDGRNALDPEVWRKAGWTFRAMGRPRA
>NZ_CP047147.1|WP_003950402.1|4652938_4654096_+|acyl-CoA-dehydrogenase
MAGAPDFDLYRLSEEHTMLRETVRALAEAKIAPHAAAVDEEARFPQEALDALTAADLHAVHVPESYGGAGADALATVLVIEEVARVCASSSLIPAVNKLGSLPVVLSGSEELKKKYLGPLAKGDGMFSYCLSEPDAGSDAAGMKTKAVRDGDFWVLNGVKRWITNAGVSEYYTVMAVTDPEKRSKGISAFVVEKGDEGVSFGAPEKKLGIKGSPTREVYFDNVRIPADRMIGAEGTGFATAMKTLDHTRITIAAQALGIAQGALDYAKGYVQERKQFGKPIGDFQGVQFMLADMAMKLEAARQLTYAAAAKSERVENDLTFFGAAAKCYASDAAMEITTDAVQLLGGYGYTRDYPVERMMRDAKITQIYEGTNQVQRIVMARNLP
>NZ_CP047147.1|WP_159313951.1|4654163_4654631_-|hypothetical-protein
MHHHGYLWAGPKERFDQEALRRPPHPEPPPAGGRPELIQRYREVAAEFPAGDLPPLETAYWLVKPPSLVRGTWGEAKEAASWLGERLAAYAPRFASAGERDVTRLARLVDAAAGQLHSGTDVSYGFYLERPTFLSLAVVTCSPNRAGPGLACPVA
>NZ_CP047147.1|WP_008417638.1|4654681_4654915_-|DUF397-domain-containing-protein
MQNGTDLYALDIHGALFVKACGGNTHPDGESCVTLARIGDGAWALGDSKRPDAKPLRFTTEELGAAGIDPARFGLGA
>NZ_CP047147.1|WP_159312997.1|4655610_4656459_+|helix-turn-helix-domain-containing-protein
MHSPPSSRVQKAREELAGRLREIRKDAGISSRELALRCGWSESKSSRIENAKTPPSDADVRAWCRACAADEQAPDLIAANRLSADAHVQWRRLQRSGLRRLQETTGDLYRETGTFRTYVSDVIPGFLQTPGYAAALLSSIADFRGTPDDVSDAVAARMRRNEVLSNGARRFSFVMEESVLRYRLCGAETMAAQLGHLLGVMDLQNVAVGFIPFSARRAVWPMPTFTIFDDTKVHADTLDAAATLTQPGQVELYARAFERLAQGAVRGAAARSLVADAVASLA
>NZ_CP047147.1|WP_159312998.1|4656540_4657065_-|hypothetical-protein
MKSTSDSLGDLFDSFQQEAFRLETLDDYSRSGNVDAYHAYLAGEPQPAGYNADWVDEVRTHTENGKRIRRVHILSRPLTEYLRFELGWGYRKNMTGGEEFFILDVTNRPNPLPGVPDFWCFDSESVAVMRYDDTGRYLGSDVPAPERAAEFIRYRDTALSHAEPFTAWWAEHGA
>NZ_CP047147.1|WP_159312999.1|4657380_4659021_+|catalase
MTEPANKDRPYLTNRQGHPVYDNQNQRTVGARGPATLENYQFLEKISHFDRERIPERVVHARGVTTFGFFEAYGKWGDEPISRYTRAKLFQEAGKRTDVAVRFSTVIGGRDSSEAARDPRGFAVKFYTEDGNWDLVGNNLGVFFIRDAIKFPDVIHSLKPDPVSHEQKPARIFDFMSQTPEAMHMLVNLFSPRGIPADYRHMQGFGVNTYKWVDAEGGTVLVKYHWVPKQGVASMTEEDAANVQADDLGHATKDLYEAIGRGDYPEWELRVQMMSDDDHPELDFDPLDDTKTWPEQDFPPRPVGRMVLDRVPGNYFAENEQAAFGTGVLVDGLDFSDDKMLVGRTFSYSDTQRYRVGPNYLQLPVNQPKAPVATNQRDGQMAYENGPDGENPEVNYEPSIMGGLREAEYPTRDEEGPVLQGRLTRARIPRTNDYLQAGQRFQLMEDWEQDDLVKNFTDLFAQCTRPVQERMIWHCLMADNELGLRVGEGIGIAPSDVAHMAPLPGQTLTEEDRVRLGRLGDNPPRDVTGLTMTHCVPDKHHVVTRR
>NZ_CP047147.1|WP_008417627.1|4659094_4659847_-|tellurium-resistance-protein-TerA
MGAGLSSDGRERKTIRLRPGGAESPARRTGAPGAEQQPPPAADAAREAAERRRRAALAKEVRLTRAEPAARLGGGGLLQVNLNWSARAEADVDLCALAEFTDGTLQVVQALGDAFGRLDAWPYIALDHDDRSGASADGETLRVNLDHHHLFRRLLFFTYLYEGSVSFRELGASVTVSGTAGTFRILLDDAPATAAGCAVALTESDGTGLTVRREVRWFDGHPELGFHELVDQAYGFGLSWTRMDKPPRLG
>NZ_CP047147.1|WP_159313000.1|4660030_4661263_+|hypothetical-protein
MTGELTDSRRLGRSLKKLAAEPALATRQAELEHLGEAVSDQDGNRLDRWAEVDLLHTFVRPESVAAATRSPEEHRAWAWLEAGLGAFVFLPLVLSWYGLTQASRAYQELVAERPAAAARPFLQLWQTGFEGHLSGVHTFGSVALGATAVIVVLLALALVHGARGAAVDRREERGRRATEDVLGRLTVTLSRTQLYLGEHRRTSPLRFAAELTESAATLRRLGQDAVRVQTELGAAAASVETAVRGAETALSAVDTSVRPLERAAGQIEKAVRESGDGIGGALGEVRGGQKELHEGIGAAAERVEDSAGALAAAQQSFTTGIEVSADVTARLLSRLDSYAERSAAADEAAGAALRQLAEQTAALRRTADRFAELTEALQEYPPGPPPEPAGREPAKKAPAALPAGAPGDAR

Crispr_ID: NZ_CP047147_27

• CRISPR_ID: NZ_CP047147_27
• CRISPR_location: 4799357-4799538
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP047147_27

Consensus_repeat	Method
AGCCCGGCCGGCGTTTGAGGCCATCT	PILER-CR

spacers of NZ_CP047147_27

>27.1|4799383|62|NZ_CP047147|PILER-CR
GTGACGCGCGCCCTGCGGCGGCCGGTCCGGCCGCGTCGCTCCTGACCGGGCCTCACCCTTCT
>27.2|4799471|42|NZ_CP047147|PILER-CR
GTGACGCGGGCGCGGGTGCCGGAGCTCAGCCGGATCATTCCC

CRISPR arrays and Neighbor proteins around NZ_CP047147_27

CRISPR arrays

The CRISPR arrays of NZ_CP047147_27

>merge|NZ_CP047147|27|4799357-4799538|PILER-CR
AGCCCGGCCGGCGTTTGAGGCCATCGGTGACGCGCGCCCTGCGGCGGCCGGTCCGGCCGCGTCGCTCCTGACCGGGCCTCACCCTTCTAGCCCGGCCGGCGCTTGAGGCCATCTGTGACGCGGGCGCGGGTGCCGGAGCTCAGCCGGATCATTCCCAGCCCGGCCGGCGTTTGAGGCCATCT

>NZ_CP047147|27|7|4799357-4799538|PILER-CR
AGCCCGGCCGGCGTTTGAGGCCATCG	GTGACGCGCGCCCTGCGGCGGCCGGTCCGGCCGCGTCGCTCCTGACCGGGCCTCACCCTTCT
AGCCCGGCCGGCGCTTGAGGCCATCT	GTGACGCGGGCGCGGGTGCCGGAGCTCAGCCGGATCATTCCC
AGCCCGGCCGGCGTTTGAGGCCATCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_159313040.1|4812470_4813784_-|MFS-transporter	unknown	unknown	gnl|CDD|340863
NZ_CP047147.1|WP_159313035.1|4797845_4798418_+|YqgE/AlgH-family-protein	unknown	unknown	gnl|CDD|234694
NZ_CP047147.1|WP_159313037.1|4803037_4804675_+|family-20-glycosylhydrolase	unknown	unknown	gnl|CDD|119333
NZ_CP047147.1|WP_146581127.1|4801249_4802206_+|ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|224096
NZ_CP047147.1|WP_159313034.1|4790847_4793235_+|UvrD-helicase-domain-containing-protein	unknown	unknown	gnl|CDD|226482
NZ_CP047147.1|WP_008404572.1|4802202_4803036_+|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl|CDD|223472
NZ_CP047147.1|WP_003950504.1|4790135_4790723_+|CGNR-zinc-finger-domain-containing-protein	unknown	unknown	gnl|CDD|378696
NZ_CP047147.1|WP_018469728.1|4788228_4789344_+|uroporphyrinogen-III-synthase	unknown	unknown	gnl|CDD|235981
NZ_CP047147.1|WP_159313038.1|4805886_4807779_+|2Fe-2S-iron-sulfur-cluster-binding-domain-containing-protein	unknown	unknown	gnl|CDD|224991
NZ_CP047147.1|WP_159313039.1|4807775_4810073_+|molybdopterin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|132240
NZ_CP047147.1|WP_003950515.1|4804993_4805890_+|dehydrogenase	unknown	unknown	gnl|CDD|366378
NZ_CP047147.1|WP_129845066.1|4786976_4788053_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_015507187.1|4813964_4814507_+|CGNR-zinc-finger-domain-containing-protein	unknown	unknown	gnl|CDD|378696
NZ_CP047147.1|WP_003950508.1|4796154_4797495_-|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	unknown	unknown	gnl|CDD|236486
NZ_CP047147.1|WP_003950506.1|4793733_4795164_+|NAD-dependent-malic-enzyme	unknown	unknown	gnl|CDD|223358
NZ_CP047147.1|WP_003950510.1|4798480_4798774_+|DUF3039-domain-containing-protein	unknown	unknown	gnl|CDD|378609
NZ_CP047147.1|WP_010642784.1|4789344_4789953_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379112
NZ_CP047147.1|WP_026048314.1|4810541_4812323_+|DEAD/DEAH-box-helicase	unknown	unknown	gnl|CDD|223989
NZ_CP047147.1|WP_159313036.1|4799913_4801218_+|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|270450
NZ_CP047147.1|WP_003950507.1|4795570_4795852_+|DNA-binding-protein-HU-1	unknown	unknown	gnl|CDD|259859

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_159313040.1|4812470_4813784_-|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	7.1824e-57
NZ_CP047147.1|WP_159313035.1|4797845_4798418_+|YqgE/AlgH-family-protein	gnl|CDD|234694	PRK00228, PRK00228, YqgE/AlgH family protein.	2.80345e-66
NZ_CP047147.1|WP_159313037.1|4803037_4804675_+|family-20-glycosylhydrolase	gnl|CDD|119333	cd06563, GH20_chitobiase-like, The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin. Chitin is degraded by a two step process: i) a chitinase hydrolyzes the chitin to oligosaccharides and disaccharides such as di-N-acetyl-D-glucosamine and chitobiose, ii) chitobiase then further degrades these oligomers into monomers. This GH20 domain family includes an N-acetylglucosamidase (GlcNAcase A) from Pseudoalteromonas piscicida and an N-acetylhexosaminidase (SpHex) from Streptomyces plicatus. SpHex lacks the C-terminal PKD (polycystic kidney disease I)-like domain found in the chitobiases. The GH20 hexosaminidases are thought to act via a catalytic mechanism in which the catalytic nucleophile is not provided by solvent or the enzyme, but by the substrate itself.	0
NZ_CP047147.1|WP_159313034.1|4790847_4793235_+|UvrD-helicase-domain-containing-protein	gnl|CDD|226482	COG3973, COG3973, Superfamily I DNA and RNA helicases [General function prediction only].	5.30297e-61
NZ_CP047147.1|WP_146581127.1|4801249_4802206_+|ABC-transporter-permease-subunit	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	2.97911e-65
NZ_CP047147.1|WP_008404572.1|4802202_4803036_+|carbohydrate-ABC-transporter-permease	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	1.46131e-79
NZ_CP047147.1|WP_003950504.1|4790135_4790723_+|CGNR-zinc-finger-domain-containing-protein	gnl|CDD|378696	pfam11706, zf-CGNR, CGNR zinc finger. This family consists of a C-terminal zinc finger domain. It seems likely to be DNA-binding given the conservation of many positively charged residues. The domain is named after a highly conserved motif found in many members of the family.	3.15972e-13
NZ_CP047147.1|WP_018469728.1|4788228_4789344_+|uroporphyrinogen-III-synthase	gnl|CDD|235981	PRK07239, PRK07239, bifunctional uroporphyrinogen-III synthetase/response regulator domain protein; Validated.	2.80936e-173
NZ_CP047147.1|WP_159313038.1|4805886_4807779_+|2Fe-2S-iron-sulfur-cluster-binding-domain-containing-protein	gnl|CDD|224991	COG2080, CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion].	1.04589e-54
NZ_CP047147.1|WP_159313039.1|4807775_4810073_+|molybdopterin-dependent-oxidoreductase	gnl|CDD|132240	TIGR03196, pucD, xanthine dehydrogenase D subunit. This gene has been characterized in B. subtilis as the molybdopterin binding-subunit of xanthine dehydrogenase (pucD), acting in conjunction with pucC, the FAD-binding subunit and pucE, the FeS-binding subunit. The more common XDH complex (GenProp0640) includes the xdhB gene which is related to pucD. It appears that most of the relatives of pucD outside of this narrow clade are involved in other processes as they are found in unrelated genomic contexts, contain the more common XDH complex and/or do not appear to process purines to allantoin.	1.05412e-165
NZ_CP047147.1|WP_003950515.1|4804993_4805890_+|dehydrogenase	gnl|CDD|366378	pfam00941, FAD_binding_5, FAD binding domain in molybdopterin dehydrogenase.	1.14535e-44
NZ_CP047147.1|WP_015507187.1|4813964_4814507_+|CGNR-zinc-finger-domain-containing-protein	gnl|CDD|378696	pfam11706, zf-CGNR, CGNR zinc finger. This family consists of a C-terminal zinc finger domain. It seems likely to be DNA-binding given the conservation of many positively charged residues. The domain is named after a highly conserved motif found in many members of the family.	1.1624e-18
NZ_CP047147.1|WP_003950508.1|4796154_4797495_-|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	gnl|CDD|236486	PRK09369, PRK09369, UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated.	0
NZ_CP047147.1|WP_003950506.1|4793733_4795164_+|NAD-dependent-malic-enzyme	gnl|CDD|223358	COG0281, SfcA, Malic enzyme [Energy production and conversion].	4.78232e-170
NZ_CP047147.1|WP_003950510.1|4798480_4798774_+|DUF3039-domain-containing-protein	gnl|CDD|378609	pfam11238, DUF3039, Protein of unknown function (DUF3039). This family of proteins with unknown function appears to be restricted to Actinobacteria.	1.92152e-35
NZ_CP047147.1|WP_010642784.1|4789344_4789953_-|GNAT-family-N-acetyltransferase	gnl|CDD|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.2432e-21
NZ_CP047147.1|WP_026048314.1|4810541_4812323_+|DEAD/DEAH-box-helicase	gnl|CDD|223989	COG1061, SSL2, DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair].	3.7338e-59
NZ_CP047147.1|WP_159313036.1|4799913_4801218_+|extracellular-solute-binding-protein	gnl|CDD|270450	cd14747, PBP2_MalE, Maltose-binding protein MalE; possesses type 2 periplasmic binding fold. This group includes the periplasmic maltose-binding component of an ABC transport system from the phytopathogen Xanthomonas citri and its related bacterial proteins. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.14162e-90
NZ_CP047147.1|WP_003950507.1|4795570_4795852_+|DNA-binding-protein-HU-1	gnl|CDD|259859	cd14435, SPO1_TF1_like, Bacteriophage SPO1-encoded TF1 binds and bends DNA. This group contains proteins related to bacillus phage SPO1-encoded transcription factor 1 (TF1), a type II DNA-binding protein related to the DNA sequence specific (IHF) and non-specific (HU) domains. Type II DNA-binding proteins bind and bend DNA as dimers. Like IHF, TF1 binds DNA specifically and bends DNA sharply. Bacteriophage SPO1-encoded TF1 recognizes SPO1 phage DNA containing 5-(hydroxymethyl)-2'-deoxyuridine as opposed to thymine, Related family members includes integration host factor (IHF) and HU, also called type II DNA-binding proteins (DNABII), which are small dimeric proteins that specifically bind the DNA minor groove, inducing large bends in the DNA and serving as architectural factors in a variety of cellular processes such as recombination, initiation of replication/transcription and gene regulation. IHF binds DNA in a sequence specific manner while HU displays little or no sequence preference. IHF homologs are usually heterodimers, while HU homologs are typically homodimers (except HU heterodimers from E. coli and other enterobacteria). HU is highly basic and contributes to chromosomal compaction and maintenance of negative supercoiling, thus often referred to as histone-like protein. IHF is an essential cofactor in phage lambda site-specific recombination, having an architectural role during assembly of specialized nucleoprotein structures (snups).	9.32606e-39

Protein sequences

>NZ_CP047147.1|WP_003950510.1|4798480_4798774_+|DUF3039-domain-containing-protein
MSTLEPERGAGTGTLVEPTPQTSSGDGDHERYAHYVQKDKIMASALDGTPVVALCGKVWVPGRDPKKYPVCPMCKEIYESMGPGGDKGKGGGDKDKK
>NZ_CP047147.1|WP_159313035.1|4797845_4798418_+|YqgE/AlgH-family-protein
MTEVSSLTGRLLVATPALADRHFDRAVVLLLDHDAEGSLGVVLNRPTPVGVGDILEGWGELAGDPGVVFQGGPVSLDSALGVAVIPGGPGCADPPLGWRPVHGAIGLVDLEAPPELLAAALGSLRIFAGYAGWGPGQLEEELVQGAWYVVESEPGDISAPRPEGLWRAVLRRQRSELAMIATYPDDPSLN
>NZ_CP047147.1|WP_003950508.1|4796154_4797495_-|UDP-N-acetylglucosamine-1-carboxyvinyltransferase
MTVNDDVLLVHGGTPLEGEIRVRGAKNLVPKAMVAALLGSAPSRLGNVPDIRDVRVVRGLLQLHGVTVRPGDEPGELVMDPSHVESANVADIDAHAGSSRIPILFCGPLLHRLGHAFIPGLGGCDIGGRPIDFHFEVLRQFGAKIEKRADGQYLEAPQRLRGTKIELPYPSVGATEQVLLTAVLAEGVTELSNAAVEPEIEDLICVLQKMGAIIAMDTDRTIRVTGVDKLGGYRHQALPDRLEAASWASAALATEGNIYVRGAQQRSMMTFLNTYRKVGGAFEIDDEGIRFWHPGGQLNAIALETDVHPGFQTDWQQPLVVALTQATGLSIIHETVYESRLGFTSALNQMGAHIQLYRECLGGSDCRFGQRNFLHSAVVSGPTRLQGADLVIPDLRGGFSYLIAALAAQGTSRVHGIDLINRGYENFLDKLVELGGKVELPGKALG
>NZ_CP047147.1|WP_003950507.1|4795570_4795852_+|DNA-binding-protein-HU-1
MNRSELVAALADRAEVTRKDADAVLAAFAEVVGDIVSKGDEKVTIPGFLTFERTHRAARTARNPQTGEPIQIPAGYSVKVSAGSKLKEAAKGK
>NZ_CP047147.1|WP_003950506.1|4793733_4795164_+|NAD-dependent-malic-enzyme
MATAPSVSYSMTVRLEVPASGTAVSQLTTAVESHGGSVTGLDVTASGHEALRIDVTIAASSTAHADEIVEGLRGIDGVVLGKVSDRTFLMHLGGKIEMASKHPIRNRDDLSMVYTPGVARVCMAIAENPEDARRLTIKRNSVAVVTDGSAVLGLGNIGPKAALPVMEGKAALFKRFAGIDAWPICLDTQDSDAIVEIVKAIAPGFAGINLEDISAPRCFEIEARLREALDIPVFHDDQHGTAIVVLAALTNALRVVGKSIGDVRVVMSGAGAAGTAILKLLLAAGVKHAVVADIHGVVHAGRDDLVGAEADSPLRWIADNTNPEGVTGTLKEAVVGADVFIGVSAPNVLDGADVAAMAEGAIVFALANPDPEVDPAVARETAAVVATGRSDFPNQINNVLVFPGVFRGLLDAQSHTVNTEMMLAAAGALADVVAEDEVNANYIIPSVFNDKVAGAVADAVSSAAKAVGAAPAPSAV
>NZ_CP047147.1|WP_159313034.1|4790847_4793235_+|UvrD-helicase-domain-containing-protein
MADVRDREISIEQDHLDQVYRRLEEKIHEAEFLMRDAARRGQVGTPGALAERDAQVFRAGIHLNRLNNEFEDFLFGRIDLLLGKDGEKGPDGAYTSVEPADDAVRPDGTADIAETLHIGRIGVLDADYAPLVIDWRAPAAAPFYRSTPVEPGRVVRRRVIRSKGRQVLGVEDDLMRPELTARLDGEPLAVVGDGALMAALGQARSHTMRDIVASIQAEQDRVIRAPAASVTLVEGGPGTGKTAVALHRAAYLLYQDRRRYAGGILIVSPTPLLVSYTEGVLPSLGEEGQVAIRALGSLVDGAEATAYDTPAAARAKGSARMVQVLRRAARGALDLGTARPAPAGEDEEREEVPEGQLDLGLPAPAGPPERLRVVAFGRRIELDAAELGRIRRNALSGTAPVNLLRPRARRLLLDALWARSGASGRHQDPELAAELRSGFDEDILSEDSFTSFLDAWWPELTPRAVLAAMADEKRLARWSRKVLNQGEVRRVARSLARLGPVGEGPLSVHDVALLDELEAVLGAPPRPRRKREADPLDHLTGLQELMPVREETQWERAERLAQERTEYTHVIVDEAQDLTPMQWRMVGRRGRQATWTVVGDPAQSSWSDPDEAAEARDEALGRRPRRRFTLTVNYRNPAEIAELASRVLALAMPGSDSPRAVRSTGVEPRFVVAGERMGETVRAEAARLLETVDGTIGVVVPMERREQAARWVAGLGERVVALGSLEAKGLEYDATVVVSPAEVADESPAGLRVLYVALTRATQELTVVSGRRDQPDADGVPDLLRDDVPAELLGE
>NZ_CP047147.1|WP_003950504.1|4790135_4790723_+|CGNR-zinc-finger-domain-containing-protein
MTGHAYRAGASARVLRFDCGRVCLDLAATAHPVERLDGPDRLRQWLAGAGLVPPGTPLERAGPGWLAAFRDLRTQIAAVVGAELDGRPPGHALDRVNAVARNPPPPPRAVRRADGTLGRGLSGDPDCQALLGAVARDAVDLLTDPGARALLRRCAGQDCPLVYLDTSRGRRRRWCSGETCGNRERVARHRRSRRG
>NZ_CP047147.1|WP_010642784.1|4789344_4789953_-|GNAT-family-N-acetyltransferase
MSMPAFLPAGPGLSLRPWRARDARELIDAYRDPLLRQFTRTWPEDEAGARAWLAREEAGARDGSRYSFAVELAAHAPDGTGPAPSGVRDPAATGLLAGCVVLKVFPHDDDRPARTDTAEVGYWTTASVRGRGLAGRAVLALADWAFTALPALTRLELLHQVDNEPSCRVAEKAGFPHHETLAPQPPVFPLPGHVHVRPRPAA
>NZ_CP047147.1|WP_018469728.1|4788228_4789344_+|uroporphyrinogen-III-synthase
MGEASPLVGFTVGVTAERRAQELGALLGRRGAEVVYAPALRVVPLADDRELREATEELVARPPEIVVASTAVGFRGWVEAAEGWGVGGALREALGGARLLARGPKVTGAVRAAGLREEWSPRSEAMEEVRERLLADGVAGLRVAVQLHGEPVPGFAEALRAAGAEVVGVPVYRWLPPADLTPVDRLVDATVRRTLDALTFTSAPAVVSVLRRAEALGLREALVDAVNGDVAVVCVGPVTARPLQEAGVEPVQPERFRLGPMVQRLCEELPARTPELAVAGHRVQLRGHAVLVDGEARPVPPAPMALLRALARRPGRVVARAELLRALPGAGRDEHAVESATARLRTALGAPELVRTVVKRGYRLAVDDPEG
>NZ_CP047147.1|WP_129845066.1|4786976_4788053_+|hypothetical-protein
MTTSRAVFRGAALTLSAGLLALSGTAYADAPGDNTTTPPPQSKPSGDTDGKGKVSAGVSQIRISQVKGGGSGKQGNLAPIDADWEPPACWYEPVFTPEELKEFVDRTGGHGDVGIHQSWYGKGLWTDHYRDGEVQDNMDDDRTEAEGYKNYNIGKDGNFWRSVAPDDSHPDSWDCGRIMFWAPDNQVPQIPNAPTPQMLAEYAYEHVKVPDTEVEVRPQARSTVNLPTWVWLDKGKFEDVVVRAELPRTNLYAETTAHPVSLTLEPGTEDAETFPADGTCRINDDGSIGSPYKKGSADQDPPCGITYLRASDEPYQLSASITWEISWEGTGGTGGDLPDGTFETTQDMTVQEIQSINR
>NZ_CP047147.1|WP_159313036.1|4799913_4801218_+|extracellular-solute-binding-protein
MKLLPRLAAPVAALVLAGLTATACAPQTSDTSSGKDEKTGDLRVWLFQEVNNGPKAKVVDRAVAAYEKAHQGSKVDVQYIPVDSRAEKIKAAFNDPSSAPDVIEYGNTDTAGYVRDGGLADISKEFAAWDEAADTDEAARASVTVDGKTYGAPYFVGVRALYYRTDLFEKHSVAVPETLDEVAAAAKKIRKAEPGLYGIAVGGAYTYGAMPFLWAHGGGLAEEKDGAYTSTLADKKSQAGIAAYTDLFGPDNCPAAKCAQMGGNDTVTAFAAGKAGMAIGGDFSHQAMEDGKVKGKYAVVPLPGTEKGEIAPAFAGGNNLGVLKSTERRSLAVDLVKELAGKKAQSELFDAMGFLPTFTDTRAEAAAEEPFVKPFVQTLDAGATFVPASPAWARIDSSLVLPTMFQEIVSGRKDVAAASRDAAKKMDDAFASAD
>NZ_CP047147.1|WP_146581127.1|4801249_4802206_+|ABC-transporter-permease-subunit
MTQTLTAPATPPVRKGGGGARPPRSGSRRPGWTPWLYLAPALVVLAGLLVYPVYQLGLISVLEYTQAQVSGGEPTSFQGLGNYQQLFTDPQFWQVLTATVVFAALCVLSTLFVGCAFAVLLTRIRALPRLALLIASLGAWATPAITGSTVWMFLFDADFGPVNRLLGLGDFSWTYGRYSAFALVLLEVVWCSFPFVMVTVYAGIRAVPTEVLEAASLDGASQWRVWRSVLAPMLRPILLVVTIQSVIWDFKIFTQIYVMTDGGGIAGQNLVLNVYAYQQAFASSEYSLGAAIGVVMLLILLAVTLVYLRLMRRQGEEL
>NZ_CP047147.1|WP_008404572.1|4802202_4803036_+|carbohydrate-ABC-transporter-permease
MKLVHRPWRLAAEAFALLAAVVVAFPLYWMVLSAFKPAGEIQSDTPRPWTLAPSLDSFRRVFQQEEFGRYFLNSLFVAGSVVVLSALIAFLAATAVTRFKFRFRTTLLIMFLVAQMVPVEALTIPLFFQMRDFGLLNTLGALILPHLAFSLPFAIWMLRGFVKAVPEALEEAALIDGASRTRFLWQILFPLVFPGLVATSVFSFISTWNDFLFAKSFIISDTSQSTLPMALLLFFKPEENDWGGIMAASTVMTVPVLVFFVLVQRRLVSGLGGAVKD
>NZ_CP047147.1|WP_159313037.1|4803037_4804675_+|family-20-glycosylhydrolase
MHHLIPAPRHHRPESGPETRLTLGPDTALRTGEGTGTAARWLRTTVGAATGLALPEAAAENPGPVVDLRITGEGGGLGAEAYRLTVSAEGVLIEGGDAAGVFWGAQTLRQLLGPDAFRRAPLNPGRAWQLGHVRIEDAPRFAWRGMMLDVARHFMPKDGVLRHLDLLAAHKLNVFHFHLTDDQGWRVDIRRHPELVRTGSWRPRSKWGHRASELWNDTPHGGYYTHDDIREIVAYAAERHITVVPEIEIPGHSQAAIAAYPELGNTDVTDTAGLGVWDTWGINPHALAPTEDTLRFYEGVFEEVLELFPSRFIHVGGDECEKDEWRRSPAAQARIAELGVGDEDGLQSWFIRHFDRWLGARGRRLVGWDEILEGGLAEGATVSSWRGYAGGIAAARAGHDVIMCPEQQVYLNYREDGGPDEPVPIGYVRTLEDVYRFEPVPPELTGAEAAHVIGVQANVWTEVLENQDRVDYQLYPRLAALAEVAWSPLPASEERDFAGFDARMETHFRRLDALGVAYRPPSGPHPWQRRPGVLGRPFEGAPQPG
>NZ_CP047147.1|WP_003950515.1|4804993_4805890_+|dehydrogenase
MTTHAPQAAASVTLPASLDEAVAALAATPAAVPVAGGTDLMASVNAGQLRPTALVGLGRVREIRGWQYLDGHALLGAGLTHARMGRPDFAALIPALAAAARAAGPPQIRNAGTLGGNIATAAPSGDTLPVLAALEATLVVASPGGGRREVSVSHLLAGMDMLRGGELIGWVRVPLLHAPQVFLKATGRTGPGRATASVALVVDPARREVRCAIGAIAPMPLRPLEAERWAASLIDWDGERGLPQEALTAFGTYVATACVPDPEVPADGGEPPKLPPAVLHLRRTVAALARRALGRALS
>NZ_CP047147.1|WP_159313038.1|4805886_4807779_+|2Fe-2S-iron-sulfur-cluster-binding-domain-containing-protein
MTDDERGEGTGAARGTSLSWGAIPHQGGEEYDDGATAFVQLPEGIADIPLAAPGQGYVPPITVTPATGPADPAATGVWSIPGAVAGGAPAPDPYAQQAGHGPDPYGTLPPQDVPEAAPGQVVADVYPDGAQVPGADGYPQPPADAFAATDAFGDTRPLTIPPGLSPDGPRPDLGAAFGGAERAGQPHGRPGIPGQQQGPGSAGQDATGHWDFGTALGESAPPAQGGTGQWAVPLAPEDVPEESGEYPLSEAAPRTGAWAAAPTHQAPATLPGGATAPWAGEAGATAPEPAPEAAPEASAGEAPGEAQGAPDGPEAEEQAESAPEADSAPETADAPAPEPEAEAETEAEAEGAGEEPGGAVEAAGEEAPEAGGLHDERPVVSYTLNVNGIDRPVTEAWIGESLLHVLRERLGLAGAKDGCSQGECGACAVRVDGRVVASCLVPAATTEGSDIHTVEGLGAAEDGGPGEPSDVQRALARHCAVQCGFCIPGMAMTIHDLLEGNPRPTDLETRQALSGNLCRCSGYRAILESVRDVVGEREASADVAAHDDASAEAEDGEPAGADQAEVAIPHQAGPADGEAPGHPYGALPDGYDGLPQPPPSYDTGGYPPHHGQDGYGYDEQGPHEQHGGQA
>NZ_CP047147.1|WP_159313039.1|4807775_4810073_+|molybdopterin-dependent-oxidoreductase
MSHDTATGIPAQADAEAAPHGLGVSLPLAEARAKTEGTFPYAADLWAEGLLWAAVLRSPHAHARVVSIDTRQAAGMPGVHAIVTHEDVPGEGLHGRYGADRPVFASEVVRHHGEPLAAVAADHPDTARMAAAAIMVEYEVLPAQTDPEEAFTAEPLHPDGNVVRHIPLRHGDQEATGETVVEGVYRIGRQDPAPVGAEAGLAVPRPDGGVELYAASTDPHADRDRAAAVYGLDPERVKVVVTGVPGATADREDPGFLLPLGLLAMRTGCPVKLAATREESFLGHAHRHPTLLRYRHHADAEGRLVRVEAQILMDCGAYTDSSRESLAAAVAFACGPYVVPHATIDGWAVRTNNPPAGHVRGEGALQVCAAYEAQMDKLAKRLGLEPAEVRARNVLATGDVLPTGQTVTCPAPVAELLQAVQDFPLPALPKDTPEEEWLLPGGPEGAGEPGAVRRGVGYGLGMVHMLGAEGADEVSTATVRVQDGRATVICAAVETGQGFTTLARQIVQETLGIDEVAVAPVDTDQPPAGPSCRSRHTWVSAGAVERAAKMVRTQLLQPLAHQFGMSTELLQITDGKITSYDGVLSTTVTEAMDGKELWATAQCRPHPTEPLDGAGQGDAFVGLVFCAVRAVVDVDVEIGSVRVVELAVAQDVGRVLNPAQIAARIEAGLTQGLGAALTENLRAPQGVLRHPDLTGYALPTALDAPDIRIVRLVEERDVVAPFGAKAASAVPVVTAPAAVASAVRAASGRPVNRLPIRPQAAVAQS
>NZ_CP047147.1|WP_026048314.1|4810541_4812323_+|DEAD/DEAH-box-helicase
MTTSASHHLSPAFPGRAPWGTAGKLRAWQQAAMDKYVQEQPRDFLAVATPGAGKTTFALTLASWMLHHHVVQQVTVVAPTEHLKKQWAEAAARIGIKLDPEYSAGPLSKEYQGVAVTYAGVGVRPMLHRNRVEQRKTLVILDEIHHAGDSKSWGEACLEAFEPATRRLALTGTPFRSDTNPIPFVTYEEGNDGIRRSAADYTYGYGSALGDGVVRPVIFLSYSGQMRWRTKAGDEIAARLGEPMTKDAVSQAWRTALDPRGDWMPNVLRAADQRLTEVRKAIPDAGALVIATDQDQARAYAKLIREITGNKATLVLSDDSGASQRIDDFSKSDDRWMVAVRMVSEGVDVPRLAVGVYATTISTPLFFAQAVGRFVRSRRRGETASVFLPTVPMLLGFANEMEVERDHVLDKPKKDGEEDPYAESEKEMDEANKEQDEDTGEQEQFSFEALESEAVFDRVLFDGAEFGMQAHPGSEEEQDYLGIPGLLEPDQVQLLLQKRQARQIAHSRKKPDSEADLLELPAERRPVVSHKELLELRKQLNTLVGAYVHQTGKPHGVIHNELRRACGGPPSAEATAGQIRQRIDKVREWATRG
>NZ_CP047147.1|WP_159313040.1|4812470_4813784_-|MFS-transporter
MTITSTPGRTEPKKPSEPAEPEAHGDRRPVPPPDPSRRNGAVLVGFTAVTNLADGVMRLALPLLAVRLTDSPALVTTASLALTLPWLLTALHIGVVVDRFDRRMLLWLAGAARVAAMGGLFAAAVTSHLTLGRLLAAGAVLGVADVLAATAGSALVPAAVAREHRPRVNAWMVGAETVGQEFAGPFVGGLLLAAGTGLALGAIGVTYAAAALLLVLLAGRFRPAAPAPGTPSVPVNTRIAEGLRLLWRDPVLRTLSLTAAALNAVWGAWLALMPLHAHQAMGLGPGEYGFLLSGLGIGGLVGAATVTWVNRLLGPRRAMLADLLGTCAMTALPALTTSLWAVAAGAFLGGMGGTLWAVNSRTLTQHKVPDALLGRYTAASRLLCYGALPIGTAASGLLAELLGTRTVFAVISVLALTTVIPFLRRVKAADLTGTSAP
>NZ_CP047147.1|WP_015507187.1|4813964_4814507_+|CGNR-zinc-finger-domain-containing-protein
MLATPALAALVEAFANTLDVDEVTDALATPEELAAWLREYEELDAPDAISPEAHRDYLALRAGLREEMGARVGDVPDPALLAAADEALAAHPVAVSVTGALRPAPGTPADRLPLTRLAIAWSSLVATGDAARLKRCAEHTCAWVFWDVSKNRSRRWCSMQVCGNRNKSRTYAARRRGEGG

Crispr_ID: NZ_CP047147_28

• CRISPR_ID: NZ_CP047147_28
• CRISPR_location: 4863416-4863700
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of NZ_CP047147_28

Consensus_repeat	Method
NCCGGCCGGNNTTNGAGG	CRT

spacers of NZ_CP047147_28

>28.1|4863434|42|NZ_CP047147|CRT
GTGGCCTCAAGCGCCGGCCGGGCTTGGAAGGTGGCCTCAAGC
>28.2|4863494|55|NZ_CP047147|CRT
GGCTGGTTGGCCGTCGTTGACCGGCAGGCTGAGCTTCGAGCCGGGCAAGACTCAG
>28.3|4863567|45|NZ_CP047147|CRT
CCGTCTTGGACGGGTGGCGGCGATCCGGACCTCAGCCACCCTCAG
>28.4|4863630|53|NZ_CP047147|CRT
CCAGTCAGTGACCGGCACCCCGGAGCCGGAGCCGGACCCGGAGCCCAGGACAG

CRISPR arrays and Neighbor proteins around NZ_CP047147_28

CRISPR arrays

The CRISPR arrays of NZ_CP047147_28

>merge|NZ_CP047147|28|4863416-4863700|CRT
GCCGGCCGGGCTTGGAAGGTGGCCTCAAGCGCCGGCCGGGCTTGGAAGGTGGCCTCAAGCGCCGGCCGGGATCGAAGTGGCTGGTTGGCCGTCGTTGACCGGCAGGCTGAGCTTCGAGCCGGGCAAGACTCAGCCCGGCCGGCGTTTGAGGCCGTCTTGGACGGGTGGCGGCGATCCGGACCTCAGCCACCCTCAGCCCGGCCGGCGTTTGAGGCCAGTCAGTGACCGGCACCCCGGAGCCGGAGCCGGACCCGGAGCCCAGGACAGCCCGGCCGGCGCTTGAGG

>NZ_CP047147|28|3|4863416-4863700|CRT
GCCGGCCGGGCTTGGAAG	GTGGCCTCAAGCGCCGGCCGGGCTTGGAAGGTGGCCTCAAGC
GCCGGCCGGGATCGAAGT	GGCTGGTTGGCCGTCGTTGACCGGCAGGCTGAGCTTCGAGCCGGGCAAGACTCAG
CCCGGCCGGCGTTTGAGG	CCGTCTTGGACGGGTGGCGGCGATCCGGACCTCAGCCACCCTCAG
CCCGGCCGGCGTTTGAGG	CCAGTCAGTGACCGGCACCCCGGAGCCGGAGCCGGACCCGGAGCCCAGGACAG
CCCGGCCGGCGCTTGAGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_010642691.1|4854586_4856032_+|amino-acid-permease	unknown	unknown	gnl|CDD|224038
NZ_CP047147.1|WP_003950567.1|4860286_4861573_-|PTS-transporter-subunit-EIIC	unknown	unknown	gnl|CDD|273923
NZ_CP047147.1|WP_003950576.1|4867951_4868272_+|quaternary-ammonium-compound-efflux-SMR-transporter-SugE	unknown	unknown	gnl|CDD|171110
NZ_CP047147.1|WP_003950563.1|4856958_4857243_+|MoaD/ThiS-family-protein	unknown	unknown	gnl|CDD|340594
NZ_CP047147.1|WP_003950579.1|4871709_4872579_+|transporter	unknown	unknown	gnl|CDD|253605
NZ_CP047147.1|WP_010642676.1|4867018_4867372_+|DUF3618-domain-containing-protein	unknown	unknown	gnl|CDD|378834
NZ_CP047147.1|WP_023417316.1|4867487_4867790_+|co-chaperone-GroES	unknown	unknown	gnl|CDD|197951
NZ_CP047147.1|WP_003950569.1|4862083_4862809_+|ribonuclease-PH	unknown	unknown	gnl|CDD|178914
NZ_CP047147.1|WP_159313055.1|4868342_4870673_-|penicillin-binding-protein	unknown	unknown	gnl|CDD|223815
NZ_CP047147.1|WP_003950565.1|4858472_4859222_+|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293802
NZ_CP047147.1|WP_008405025.1|4872623_4873634_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|213234
NZ_CP047147.1|WP_003950573.1|4866403_4866871_-|thioredoxin-dependent-thiol-peroxidase	unknown	unknown	gnl|CDD|224146
NZ_CP047147.1|WP_003950564.1|4857242_4858193_+|cysteine-synthase	unknown	unknown	gnl|CDD|273463
NZ_CP047147.1|WP_003950568.1|4861739_4861973_+|PTS-transporter-subunit-EIIB	unknown	unknown	gnl|CDD|238130
NZ_CP047147.1|WP_030773162.1|4870895_4871717_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|226953
NZ_CP047147.1|WP_010642679.1|4863731_4864334_+|RdgB/HAM1-family-non-canonical-purine-NTP-pyrophosphatase	unknown	unknown	gnl|CDD|234648
NZ_CP047147.1|WP_159313054.1|4859435_4860281_+|nucleotidyltransferase-domain-containing-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_003950561.1|4856132_4856567_+|M67-family-metallopeptidase	unknown	unknown	gnl|CDD|163701
NZ_CP047147.1|WP_003950572.1|4864731_4866231_-|glycine-betaine/L-proline-transporter-ProP	unknown	unknown	gnl|CDD|340924
NZ_CP047147.1|WP_003950570.1|4862941_4863325_+|hypothetical-protein	unknown	unknown	gnl|CDD|227406

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_010642691.1|4854586_4856032_+|amino-acid-permease	gnl|CDD|224038	COG1113, AnsP, Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism].	0
NZ_CP047147.1|WP_003950567.1|4860286_4861573_-|PTS-transporter-subunit-EIIC	gnl|CDD|273923	TIGR02002, PTS_system_glucose-specific_IIABC_component, PTS system, glucose-specific IIBC component. This model represents the combined B and C domains of the PTS transport system enzyme II specific for glucose transport. Many of the genes in this family also include an A domain as part of the same polypeptide and thus should be given the name "PTS system, glucose-specific IIABC component" while the B. subtilus enzyme also contains an enzyme III domain which appears to act independently of the enzyme II domains. This family is most closely related to the N-acetylglucosamine-specific PTS enzymes (TIGR01998). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	5.48638e-135
NZ_CP047147.1|WP_003950576.1|4867951_4868272_+|quaternary-ammonium-compound-efflux-SMR-transporter-SugE	gnl|CDD|171110	PRK11431, PRK11431, quaternary ammonium compound efflux SMR transporter SugE.	1.18024e-29
NZ_CP047147.1|WP_003950563.1|4856958_4857243_+|MoaD/ThiS-family-protein	gnl|CDD|340594	cd17074, Ubl_CysO_like, ubiquitin-like (Ubl) domain found in Mycobacterium tuberculosis CysO and similar proteins. CysO, also termed 9.5 kDa culture filtrate antigen cfp10A, together with CysM (Cysteine synthase M), forms a protein complex CysM-CysO that represents a new cysteine biosynthetic pathway in Mycobacterium tuberculosis. The replacement of the acetyl group of O-acetylserine by CysO thiocarboxylate to generate a protein-bound cysteine is catalyzed by CysM in a pyridoxal 5?-phosphate (PLP)-dependent manner. The family also includes QbsE that functions as the sulfide donor for the biosynthesis of thioquinolobactin in Pseudomonas fluorescens. A JAMM motif protein QbsD catalyzes removal of the carboxy-terminal dipeptide from QbsE. Both CysO and QbsE are similar to prokaryotic sulfur carrier proteins such as ThiS and MoaD, containing the beta-grasp ubiquitin-like fold.	6.6805e-42
NZ_CP047147.1|WP_003950579.1|4871709_4872579_+|transporter	gnl|CDD|253605	pfam06182, ABC2_membrane_6, ABC-2 family transporter protein. This family acts as the transmembrane domain (TMD) of ABC transporters. The family includes proteins responsible for the transport of herbicides.	2.39766e-59
NZ_CP047147.1|WP_010642676.1|4867018_4867372_+|DUF3618-domain-containing-protein	gnl|CDD|378834	pfam12277, DUF3618, Protein of unknown function (DUF3618). This domain family is found in bacteria, and is approximately 50 amino acids in length.	9.91538e-11
NZ_CP047147.1|WP_023417316.1|4867487_4867790_+|co-chaperone-GroES	gnl|CDD|197951	smart00883, Cpn10, Chaperonin 10 Kd subunit. The chaperonins are 'helper' molecules required for correct folding and subsequent assembly of some proteins. These are required for normal cell growth, and are stress-induced, acting to stabilise or protect disassembled polypeptides under heat-shock conditions. Type I chaperonins present in eubacteria, mitochondria and chloroplasts require the concerted action of 2 proteins, chaperonin 60 (cpn60) and chaperonin 10 (cpn10). The 10 kDa chaperonin (cpn10 - or groES in bacteria) exists as a ring-shaped oligomer of between six to eight identical subunits, while the 60 kDa chaperonin (cpn60 - or groEL in bacteria) forms a structure comprising 2 stacked rings, each ring containing 7 identical subunits. These ring structures assemble by self-stimulation in the presence of Mg2+-ATP. The central cavity of the cylindrical cpn60 tetradecamer provides as isolated environment for protein folding whilst cpn-10 binds to cpn-60 and synchronizes the release of the folded protein in an Mg2+-ATP dependent manner. The binding of cpn10 to cpn60 inhibits the weak ATPase activity of cpn60.	8.91339e-24
NZ_CP047147.1|WP_003950569.1|4862083_4862809_+|ribonuclease-PH	gnl|CDD|178914	PRK00173, rph, ribonuclease PH; Reviewed.	2.01732e-169
NZ_CP047147.1|WP_159313055.1|4868342_4870673_-|penicillin-binding-protein	gnl|CDD|223815	COG0744, MrcB, Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane].	3.13887e-139
NZ_CP047147.1|WP_003950565.1|4858472_4859222_+|MBL-fold-metallo-hydrolase	gnl|CDD|293802	cd07716, RNaseZ_short-form-like_MBL-fold, uncharacterized bacterial subgroup of Ribonuclease Z, short form; MBL-fold metallo-hydrolase domain. The tRNA maturase RNase Z (also known as tRNase Z or 3' tRNase) catalyzes the endonucleolytic removal of the 3' extension of the majority of tRNA precursors. Two forms of RNase Z exist in eukaryotes, one long (ELAC2) and one short form (ELAC1), the former may have resulted from a duplication of the shorter enzyme. Only the short form exists in bacteria. Members of this bacterial subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	4.14449e-84
NZ_CP047147.1|WP_008405025.1|4872623_4873634_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|213234	cd03267, ABC_NatA_like, ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA. NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.	9.52017e-125
NZ_CP047147.1|WP_003950573.1|4866403_4866871_-|thioredoxin-dependent-thiol-peroxidase	gnl|CDD|224146	COG1225, Bcp, Peroxiredoxin [Posttranslational modification, protein turnover, chaperones].	2.2015e-66
NZ_CP047147.1|WP_003950564.1|4857242_4858193_+|cysteine-synthase	gnl|CDD|273463	TIGR01136, Cysteine_synthase, cysteine synthase. This model discriminates cysteine synthases (EC 2.5.1.47) (both CysK and CysM) from cystathionine beta-synthase, a protein found primarily in eukaryotes and carrying a C-terminal CBS domain lacking from this protein. Bacterial proteins lacking the CBS domain but otherwise showing resemblamnce to cystathionine beta-synthases and considerable phylogenetic distance from known cysteine synthases were excluded from the seed and score below the trusted cutoff. [Amino acid biosynthesis, Serine family].	5.57894e-139
NZ_CP047147.1|WP_003950568.1|4861739_4861973_+|PTS-transporter-subunit-EIIB	gnl|CDD|238130	cd00212, PTS_IIB_glc, PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIB PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.	1.66536e-24
NZ_CP047147.1|WP_030773162.1|4870895_4871717_+|ABC-transporter-permease	gnl|CDD|226953	COG4587, COG4587, ABC-type uncharacterized transport system, permease component [General function prediction only].	5.58677e-29
NZ_CP047147.1|WP_010642679.1|4863731_4864334_+|RdgB/HAM1-family-non-canonical-purine-NTP-pyrophosphatase	gnl|CDD|234648	PRK00120, PRK00120, dITP/XTP pyrophosphatase; Reviewed.	6.35697e-103
NZ_CP047147.1|WP_003950561.1|4856132_4856567_+|M67-family-metallopeptidase	gnl|CDD|163701	cd08070, MPN_like, Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding). This family contains archaeal and bacterial MPN (also known as Mov34, PAD-1, JAMM, JAB, MPN+)-like domains. These domains contain the signature JAB1/MPN/Mov34 metalloenzyme (JAMM) motif, EXnHS/THX7SXXD, which is involved in zinc ion coordination and provides the active site for isopeptidase activity for the release of ubiquitin from ubiquitinated proteins (thus having deubiquitinating (DUB) activity) that are tagged for degradation. The JAMM proteins likely hydrolyze ubiquitin conjugates in a manner similar to thermolysin, in which the zinc-polarized aqua ligand serves as the nucleophile, compared with the classical DUBs that do so with a cysteine residue in the active site.	1.90861e-37
NZ_CP047147.1|WP_003950572.1|4864731_4866231_-|glycine-betaine/L-proline-transporter-ProP	gnl|CDD|340924	cd17366, MFS_ProP, Proline/betaine transporter of the Major Facilitator Superfamily of transporters. This subfamily is composed of Escherichia coli proline/betaine transporter, also called proline porter II (PPII), and similar proteins. ProP is a proton symporter that senses osmotic shifts and responds by importing osmolytes such as proline, glycine betaine, stachydrine, pipecolic acid, ectoine and taurine. It is both an osmosensor and an osmoregulator which is available to participate early in the bacterial osmoregulatory response. The ProP subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	0
NZ_CP047147.1|WP_003950570.1|4862941_4863325_+|hypothetical-protein	gnl|CDD|227406	COG5074, COG5074, t-SNARE complex subunit, syntaxin [Intracellular trafficking and secretion].	0.000981656

Protein sequences

>NZ_CP047147.1|WP_003950570.1|4862941_4863325_+|hypothetical-protein
MPTSRRLATATAGAALLVPLLLGCGALEKAADCVRTADRIADSVADLQRAADGAAEDPQQASEALDRIDKNVDDIQKDTGDADVKKAVDHLDTAVGNVRASLEKGDEVPDVSPVVDAAGELTKVCTP
>NZ_CP047147.1|WP_003950569.1|4862083_4862809_+|ribonuclease-PH
MDRIDGRTPAQLRPLTIERSWSKHAEGSVLVAFGDTKVLCTASFTEGVPRWRKGSGEGWVTAEYSMLPRATNTRGDRESVRGKIGGRTHEISRLIGRSLRAVIDYKALGENTIVLDCDVLQADGGTRTAAITGAYVALADAISWAQGKKIIKPGRKPLTGSVAAVSVGIVGSTPLLDLCYEEDVRAETDMNVVCTGDGRFVEVQGTAEGAPFDRTELDALLDLGATGCADLTKGQLAALAE
>NZ_CP047147.1|WP_003950568.1|4861739_4861973_+|PTS-transporter-subunit-EIIB
MASKAEKIVAALGGIDNIDEVEGCITRLRTEVHDPSKVDEAALKAAGAHGVVKMGTAVQVVIGTDADPIAADIEDLM
>NZ_CP047147.1|WP_003950567.1|4860286_4861573_-|PTS-transporter-subunit-EIIC
MSTANEALPRKRWWNSLFQGLQKMGRSLQLPIAVLPAAGILNRLGQPDVFGDEGLGWTGVAKVMAGAGGGLLDPNIGLPLLFCVGVAIGMAKKADGSTALAAVAGFLVYYNVLQQFPKDCPADTKDVLAGCQAADGSVVAYEYQNPGVFGGIVIGLLAAYFWQRFHRTRLVDWLGFFNGRRLVPIIMAFVAIAFAAICLWIWPPIGDGLESFSDWLIGLGSWGAGIFGVANRALLVIGLHQFLNVPIWFQFGSYTTPDGQVVHGDITRFLAGDPTAGQFTSGFFPIMMFALPAAALAIAHSAKPHRRKEVGGLMLSVGLTSFVTGITEPLEYSFLFIAPVLYVIHALLTGVSMAVTWAFGVHDGFSFSAGLIDYVINWGLATKPWLIIPIGLAFAVVYYVVFRVLITKLDLKTPGREDEEEVEDTTKA
>NZ_CP047147.1|WP_159313054.1|4859435_4860281_+|nucleotidyltransferase-domain-containing-protein
MPRTPAPRPSASPALDARVALLRRAAHAEPRLEGVLLYGSWTTGEADAYSDIEAYLFLGEGHADSFDGPGFLRALGRPALAHTNQFGILAVVFEDDLMRGEFHFEEAGAGIAAVEGWQGMVHLPDPDAAVLLDRTGRLTKAAARLTAPLAPEPVESAAHLTGELANWTLMLAHLLARREDARAHNLLHAMVAPLQLKLCRLLRGTTDHWLTPSRAAERDLPAADLARYTATTAPLAAAALRAAARASWQWSRELAAEAHGRWGTPVPEALHARIAGLLARD
>NZ_CP047147.1|WP_003950565.1|4858472_4859222_+|MBL-fold-metallo-hydrolase
MKLTVVGCSGSFPSAESACSSYLVEADGFQLLLDMGNGALGELQRHTGLYDLDAVFLSHLHADHCIDMCAYFVARYYRHGDGPCDALPVYGPEGTQQRLITAYGDSSAEHMPEVFDFRTLKEDAFDLGPFRIRTVRVPHPVEAYAIRVEHDGRSLTYSGDTGPCAELDALAAGTDLYLCEAAFTHGKENIPDLHLNGREAGESAQRAGAGRLLLTHIPPWTDPRTNLTDAREVYDGPAALAEPGVTYTV
>NZ_CP047147.1|WP_003950564.1|4857242_4858193_+|cysteine-synthase
MRYDSPLAAVGNTPLVRLPRLSPSDDVRIWAKLEDRNPTGSVKDRPALHMVEQAEKDGRLTPGCTILEPTSGNTGISLAMAARLKGYRIVCVMPENTSQERRDLLAMWGAEIVSSPAAGGSNTAVRVAKELAAEHPDWVMLYQYGNPDNAGAHYATTGPEILADLPSVTHFVAGLGTTGTLMGVGRYLREQKPGIAIVAAEPRYDDVVYGLRNLDEGFVPELYDASVLTSRFSVGSADAVSRTRELLQQEGIFAGVSTGAALHAAIGVGRKAVKAGESADIVFVVADGGWKYLSTGVYTAATTEEAIETLHGQLWA
>NZ_CP047147.1|WP_003950563.1|4856958_4857243_+|MoaD/ThiS-family-protein
MAIEVRIPTILRTYTDGAKTVEGSGTTLAELIDDLETRHAGIKERIVDGDQLRRFVNVYLNDEDVRFLDSIDTKVADGDNVTILPAVAGGSAAL
>NZ_CP047147.1|WP_003950561.1|4856132_4856567_+|M67-family-metallopeptidase
MLTLTQALHDQIVAHARADHPDEACGIVAGPAGSGRPERFIPMLNAARSPTFYEFDSMDLLKLYRELDDRDEEPVIVYHSHTATEAYPSRTDVTYANEPGAHYVLVSTADTDDAGPFQFRSFRIVDGEITEEDVQVVAAYPAAG
>NZ_CP047147.1|WP_010642691.1|4854586_4856032_+|amino-acid-permease
MSSTQVDTVSDGEPGPGRGGPSTPHGGEGYQRGLGARQIQMIAIGGAIGTGLFLGAGKAISKAGPSLILAYAIAGLVIFFIMRALGELLMYRPVSGSFSEYAREFIGPFAGFVTGWTYWLFWVVTGITEVTAAAQYMTYWFDVPQWVSALLFTIILYGANLISVKIFGELEFWFSMVKVTAIVGMILICVGILTLGFSDAGDTATVAHLWNQGGFFPEGIGGTLMTLQIVMFAFLAVELVGVTAGESKDPEKTLPKAINTVPWRIAVFYVGALVMILSVVPWTEFQPGISPFVAAFEKMGLGVGAAIVNFVVLTAALSSCNSGMYSTGRMLRDLALNGQGPKFFTRLTRSGTPLVGTTFSAALMMVGVWINYQWPGEAFNYVVSFATISGMWAWVMILVCQIRYRAKADRGELPVSSFRAPGAPFTSWFALCFLALVVVMMGIDPDTRISLYCAPLWAAILLVSYRVLRSRDPQNAAFAKR
>NZ_CP047147.1|WP_010642679.1|4863731_4864334_+|RdgB/HAM1-family-non-canonical-purine-NTP-pyrophosphatase
MTRLILATRNTGKITELRAILADAGLSHELVGADAYPEIPDVKETGVTFAENALLKAHALAQATGLPAVADDSGLCVEVLGGAPGIFSARWAGRHGDDQANLDLLLAQLSDIDDPHRAAYFACAAALALPDGTERVVEGRLTGTLRHAPAGTHGFGYDPILQPDGETRTCAELTPAEKNAISHRGKAFRALAPIVQELLG
>NZ_CP047147.1|WP_003950572.1|4864731_4866231_-|glycine-betaine/L-proline-transporter-ProP
MADTGPQTGGDPEAVKRHPRLFRAARQRRNPRLRRSDITVTDERAVKRAVKAASLGNAMEWFDFGIYSYLAVTIGHVFFPSGNDTVQLLSSFATFAVAFLVRPLGGMFFGPMGDRLGRKKVLALTMILMALGTFCIGLIPSYASIGFWAPLLLILFRLVQGFSTGGEYGGASTFIAEYAPDKRRGFFGSFLELGTLLGYTGAAGLVTALYAVLDDGAMESWGWRIPFLVAGPLGFVGIYLRLKLDETPAFQKLEDGTSAHASEAADGVETTHKGDLAKIFRRYWPSLILCIALVGAYNITDYMLLSYMPTYLSDEMGYDESHGLLILIGVMVLLMLIINQVGKLSDRFGRKPLLMTGMISFFFLSIPSFLLVKQGSLLAVSGGMLMLGLSLVCLLGTMSAALPALFPTPVRYGSLSVGYNLSASLFGGTTPLVITGLIGLTGDDMMPAYYAMAASLVGIIAVACMKETAHRPLAGSPPSVATEEEAREILDAQSPDPKF
>NZ_CP047147.1|WP_003950573.1|4866403_4866871_-|thioredoxin-dependent-thiol-peroxidase
MSERLKPGDTAPAFTLPDADGNEVSLASHQGRKVIVYFYPAALTPGCTKQACDFTDNLDALASAGYDVIGVSPDKPEKLAKFREKEDLKVTLVGDPSKETLAAYGAFGEKKLYGKTVTGVIRSTVVVGEDGTVEHAFYNVKATGHVAKIMRDLGV
>NZ_CP047147.1|WP_010642676.1|4867018_4867372_+|DUF3618-domain-containing-protein
MGTDDDGGSAVSDARTPAQIEADIKRRRDTLAETLDEIGVRVHPKTIVGDAKAQVASRVDATLGRAYVGVNRALSQVRSGFTREDGSVRPERVIPVALVAVGIVGLVVASSRRDSGK
>NZ_CP047147.1|WP_023417316.1|4867487_4867790_+|co-chaperone-GroES
MLHDRVLVRTDIPEGERRSTGGIVIPATAAVGRRLGWAEVVAVGQNVRAVEPGDRVLYDPEDRAEVEVRGVAYVLMRERDLHAVAADRFEGSEDATGLYL
>NZ_CP047147.1|WP_003950576.1|4867951_4868272_+|quaternary-ammonium-compound-efflux-SMR-transporter-SugE
MAWILLLVAGLLEVGWSIGMKYTEGFTRLWPSVFTAAGIVASMVLLAQAARTLPIGTAYGVWVGIGAAGAAILGMLVLGEPATAARIFFVCLLIVAVVGLKLTSGH
>NZ_CP047147.1|WP_159313055.1|4868342_4870673_-|penicillin-binding-protein
MSEERQQPDGADEERQRWPGWEERDPDAGGPRKHGIRRFLPGWRLVLGSFLALVVLVCGGFLIGYLLVDIPAANAAATQQSNVYLYADGTQLASDGDVNRENISLSDLPKPVRHAVLAAEDRDFYTGSAVDPQAMIRGAWKTVTGKGKQSGSTITQQYVKNYYLDQDQTVTRKAKEFFIAIKLDRETSKDEILEGYLNTSYFGRNAYGIQAAAQAYYGIDARDLNTAQGAYLASLLNAPSAYDVIAQPANRSRAEARWNYVLDGMVKENWLTESGRARLSFPTPDEQHLPRGLSGQRGYLVQAVDAYLVSHGVVSEAQLAKGGHRITTTLVKGHQDALVKAVDDKLISKLDKKERKADRNVRAGGVAIDPDTGKVLAMYGGIDYTEQYVNNATRRDYQVGSTFKPFVLTAALQHKARTQDGRTINPNARYDGTNKRRVEGWTGGPYEPENEDERDYGDITLKVATDRSVNAVYAQLAVDVGPEKVKDTAIALGLPKATPDLQPYPSIALGTATASVLDMAEAYATLADHGRHRSHRLVQEISHLGEKLELPQERVQGAVTRRAADTTTEVLRSVVRGGTGMAAREAGRPAAGKTGTAEEDTAAWFAGYTPDLTTVIAVMGQDPKSGAHTPLYGALGLPRINGGGPPAEIWAQFTRAALAGQPVRDFQLDADRSAEDSPTASPSETGAASRGPRDPDASGEPDGDGSSSREPGGDSPSESGGDTEVPPGMEEDPGRNGDPAPPGEPAPDTPAPAPAREPRETLAPLATPDLDPPQAG
>NZ_CP047147.1|WP_030773162.1|4870895_4871717_+|ABC-transporter-permease
MAHGPGRAALYAAVAAKGFRRYATYRAATLAGIFTNTVFGVILAQTYLALWAERPGLGGYDQAQALTFVWIGQSLHMAVAAMGGGSEEELMERIRSGDIAVDLYRPVDLQLWWLAQDAGRACFQLFARGALPLAFGALVFDLALPASPGTWIAFLTAVALGLLVSFGIRYLVALSAFWLLDGAGVGQLAWLVGMFFSGMLLPLNVFPGLLGEVARVLPWSSILQLPADVLLGVHTGTGLLGVYAFQLAWAAALLAAGRALQSLATRRVVVQGG
>NZ_CP047147.1|WP_003950579.1|4871709_4872579_+|transporter
MADPAAPPRPAPDPVDARFGSPLTEGLRTYRLVVAMWVRSTLTYRASFAMALCVAVAANGLDFVAILLMFSHVDRLGGFTLGEVAFLYGTSATAFGLAHLTVGSMDRLGRRIRDGSLDTLLVRPVPVLAQLAADRFALRRLGRITQGALVLAYALTVLEIDWTATRLLMVPMMLVSGAALFGALFVAGAVFQFYAQDAAEVQNAFTYGGTTLLQYPPTVFTRELVASVTFVLPLAFVNWVPASYVLDRPLPLGLPVQAAFAPPLVAAVCCVAAGLLWRVGLRAYRSTGS
>NZ_CP047147.1|WP_008405025.1|4872623_4873634_+|ATP-binding-cassette-domain-containing-protein
MDATERPVADLPAQRDGQEVIHLDRVEKVFEVRRRAGLLRREKREVRAVDGLSFSVGRGEVVGFVGPNGAGKSTTIKMLTGILTPSAGTLRVAGVEPARDRARLARRIGVVFGQRTTLWWDLPLLDSYQLIHRMYRVPDARYRENLDRCVELLGLGDLLDVPVRQLSLGQRMRGDIAAALLHDPEVLYLDEPTIGLDVVSKANVRRFLADLNAERGTTVLLTTHDLTDIEQLCRRVMVIDHGRLMYDGEVAGLHRIAEVERTLVVDLATELAPIALESARTVKVEGPRQWLAFPAGQPAAPIVAEIAAGWPLVDLSLREPDIEDVISLMYAGRSAG

Crispr_ID: NZ_CP047147_29

• CRISPR_ID: NZ_CP047147_29
• CRISPR_location: 5066632-5066719
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP047147_29

Consensus_repeat	Method
GGCCTCAAGCGCCGGCCGGGCTG	CRISPRCasFinder

spacers of NZ_CP047147_29

>29.1|5066655|42|NZ_CP047147|CRISPRCasFinder
TTCTTCGGGGGTGCTCGCCGCTTTCGCGCGCCGGTCACCGAT

CRISPR arrays and Neighbor proteins around NZ_CP047147_29

CRISPR arrays

The CRISPR arrays of NZ_CP047147_29

>merge|NZ_CP047147|29|5066632-5066719|CRISPRCasFinder
GGCCTCAAGCGCCGGCCGGGCTGTTCTTCGGGGGTGCTCGCCGCTTTCGCGCGCCGGTCACCGATGGCCTCAAGCGCCGGCCGGGCTT

>NZ_CP047147|29|22|5066632-5066719|CRISPRCasFinder
GGCCTCAAGCGCCGGCCGGGCTG	TTCTTCGGGGGTGCTCGCCGCTTTCGCGCGCCGGTCACCGAT
GGCCTCAAGCGCCGGCCGGGCTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_018893589.1|5070175_5070793_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_CP047147.1|WP_003950753.1|5071209_5072226_-|ribosome-small-subunit-dependent-GTPase-A	unknown	unknown	gnl|CDD|206747
NZ_CP047147.1|WP_010642418.1|5064846_5066580_+|sel1-repeat-family-protein	unknown	unknown	gnl|CDD|276807
NZ_CP047147.1|WP_003950745.1|5060604_5061165_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_129845026.1|5057168_5058350_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|187551
NZ_CP047147.1|WP_003950749.1|5067678_5069130_+|catalase	unknown	unknown	gnl|CDD|163712
NZ_CP047147.1|WP_003950750.1|5069225_5070032_-|histidinol-phosphatase	unknown	unknown	gnl|CDD|273949
NZ_CP047147.1|WP_010642425.1|5058457_5058940_+|molybdenum-cofactor-biosynthesis-protein-MoaE	unknown	unknown	gnl|CDD|238385
NZ_CP047147.1|WP_003950754.1|5072243_5073596_-|3-phosphoshikimate-1-carboxyvinyltransferase	unknown	unknown	gnl|CDD|235037
NZ_CP047147.1|WP_159313963.1|5061345_5064342_+|UPF0182-family-protein	unknown	unknown	gnl|CDD|377101
NZ_CP047147.1|WP_049977100.1|5054869_5055403_-|NUDIX-hydrolase	unknown	unknown	gnl|CDD|239646
NZ_CP047147.1|WP_010642433.1|5054053_5054806_+|AIM24-family-protein	unknown	unknown	gnl|CDD|376704
NZ_CP047147.1|WP_003950744.1|5059410_5060511_+|PDZ-domain-containing-protein	unknown	unknown	gnl|CDD|226011
NZ_CP047147.1|WP_128825885.1|5075618_5076266_+|hydrolase	unknown	unknown	gnl|CDD|226101
NZ_CP047147.1|WP_010642429.1|5055399_5056884_-|zinc-dependent-metalloprotease	unknown	unknown	gnl|CDD|378392
NZ_CP047147.1|WP_003950755.1|5073638_5074361_-|M50-family-metallopeptidase	unknown	unknown	gnl|CDD|315961
NZ_CP047147.1|WP_003950752.1|5070758_5071082_-|multidrug-efflux-SMR-transporter	unknown	unknown	gnl|CDD|224987
NZ_CP047147.1|WP_003950748.1|5067114_5067531_-|transcriptional-repressor	unknown	unknown	gnl|CDD|223806
NZ_CP047147.1|WP_075986338.1|5074450_5075323_+|SOS-response-associated-peptidase	unknown	unknown	gnl|CDD|376837
NZ_CP047147.1|WP_008415685.1|5059127_5059385_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_018893589.1|5070175_5070793_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.2016e-08
NZ_CP047147.1|WP_003950753.1|5071209_5072226_-|ribosome-small-subunit-dependent-GTPase-A	gnl|CDD|206747	cd01854, YjeQ_EngC, Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases. YjeQ (YloQ in Bacillus subtilis) is a ribosomal small subunit-dependent GTPase; hence also known as RsgA. YjeQ is a late-stage ribosomal biogenesis factor involved in the 30S subunit maturation, and it represents a protein family whose members are broadly conserved in bacteria and have been shown to be essential to the growth of E. coli and B. subtilis. Proteins of the YjeQ family contain all sequence motifs typical of the vast class of P-loop-containing GTPases, but show a circular permutation, with a G4-G1-G3 pattern of motifs as opposed to the regular G1-G3-G4 pattern seen in most GTPases. All YjeQ family proteins display a unique domain architecture, which includes an N-terminal OB-fold RNA-binding domain, the central permuted GTPase domain, and a zinc knuckle-like C-terminal cysteine domain.	8.63681e-90
NZ_CP047147.1|WP_010642418.1|5064846_5066580_+|sel1-repeat-family-protein	gnl|CDD|276807	sd00010, SLR, Sel1-like repeat. Sel1-like repeats (SLRs) share similar alpha-helical conformations with Tetratricopeptide repeats (TPRs), but with different consensus sequence lengths and superhelical topologies. SLRs contain 36 to 44 amino acids and are present in bacteria and eukaryotes but not in archaea. SLR proteins are involved in a variety of functions, and many serve as adaptor proteins for the assembly of macromolecular complexes. The SLR family was named after the Caenorhabditis elegans Sel1 protein which is predicted to fold into 11 SLRs, a transmembrane domain, and an N-terminal signal sequence. The human Sel1L protein contains an additional fibronectin type-II domain and an N-terminal PEST sequence. Its downregulation is associated with the development of breast and pancreatic carcinomas.	1.75562e-14
NZ_CP047147.1|WP_010642429.1|5055399_5056884_-|zinc-dependent-metalloprotease	gnl|CDD|378392	pfam10103, Zincin_2, Zincin-like metallopeptidase. This family of proteins has a conserved HEXXH motif, suggesting they are putative peptidases of zincin fold. The structure of this family has similarity to Peptidase_M1 (pfam01433, Structure 3CMN).	3.73364e-169
NZ_CP047147.1|WP_129845026.1|5057168_5058350_+|SDR-family-oxidoreductase	gnl|CDD|187551	cd05240, UDP_G4E_3_SDR_e, UDP-glucose 4 epimerase (G4E), subgroup 3, extended (e) SDRs. Members of this bacterial subgroup are identified as possible sugar epimerases, such as UDP-glucose 4 epimerase. However, while the NAD(P)-binding motif is fairly well conserved, not all members retain the canonical active site tetrad of the extended SDRs. UDP-glucose 4 epimerase (aka UDP-galactose-4-epimerase), is a homodimeric extended SDR. It catalyzes the NAD-dependent conversion of UDP-galactose to UDP-glucose, the final step in Leloir galactose synthesis. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	2.99323e-91
NZ_CP047147.1|WP_003950749.1|5067678_5069130_+|catalase	gnl|CDD|163712	cd08156, catalase_clade_3, Clade 3 of the heme-binding enzyme catalase. Catalase is a ubiquitous enzyme found in both prokaryotes and eukaryotes, which is involved in the protection of cells from the toxic effects of peroxides. It catalyzes the conversion of hydrogen peroxide to water and molecular oxygen. Catalases also utilize hydrogen peroxide to oxidize various substrates such as alcohol or phenols. Clade 3 catalases are the most abundant subfamily and are found in all three kingdoms of life; they have a relatively small subunit size of 43 to 75 kDa, and bind a protoheme IX (heme b) group buried deep inside the structure. Clade 3 catalases also bind NADPH as a second redox-active cofactor. They form tetramers, and in eukaryotic cells, catalases are located in peroxisomes.	0
NZ_CP047147.1|WP_003950750.1|5069225_5070032_-|histidinol-phosphatase	gnl|CDD|273949	TIGR02067, his_9_HisN, histidinol-phosphatase, inositol monophosphatase family. This subfamily belongs to the inositol monophosphatase family (pfam00459). The members of this family consist of no more than one per species and are found only in species in which histidine is synthesized de novo but no histidinol phosphatase can be found in either of the two described families (TIGR01261, TIGR01856). In at least one species, the member of this family is found near known histidine biosynthesis genes. The role as histidinol-phosphatase wsa first proven in Corynebacterium glutamicum. [Amino acid biosynthesis, Histidine family].	6.95135e-101
NZ_CP047147.1|WP_010642425.1|5058457_5058940_+|molybdenum-cofactor-biosynthesis-protein-MoaE	gnl|CDD|238385	cd00756, MoaE, MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. Moco contains a tricyclic pyranopterin, termed molybdopterin (MPT), which carries the cis-dithiolene group responsible for molybdenum ligation. This dithiolene group is generated by MPT synthase in the second major step in Moco biosynthesis. MPT synthase is a heterotetramer consisting of two large (MoaE) and two small (MoaD) subunits.	1.83232e-47
NZ_CP047147.1|WP_159313963.1|5061345_5064342_+|UPF0182-family-protein	gnl|CDD|377101	pfam03699, UPF0182, Uncharacterized protein family (UPF0182). This family contains uncharacterized integral membrane proteins.	0
NZ_CP047147.1|WP_049977100.1|5054869_5055403_-|NUDIX-hydrolase	gnl|CDD|239646	cd03674, Nudix_Hydrolase_1, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity. They also contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, U=I, L or V), which forms a structural motif that functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	1.31101e-40
NZ_CP047147.1|WP_010642433.1|5054053_5054806_+|AIM24-family-protein	gnl|CDD|376704	pfam01987, AIM24, Mitochondrial biogenesis AIM24. In eukaryotes, this domain is involved in mitochondrial biogenesis. Its function in prokaryotes in unknown.	4.69794e-30
NZ_CP047147.1|WP_003950744.1|5059410_5060511_+|PDZ-domain-containing-protein	gnl|CDD|226011	COG3480, SdrC, Predicted secreted protein containing a PDZ domain [Signal transduction mechanisms].	3.41027e-78
NZ_CP047147.1|WP_128825885.1|5075618_5076266_+|hydrolase	gnl|CDD|226101	COG3571, COG3571, Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only].	1.80599e-25
NZ_CP047147.1|WP_003950754.1|5072243_5073596_-|3-phosphoshikimate-1-carboxyvinyltransferase	gnl|CDD|235037	PRK02427, PRK02427, 3-phosphoshikimate 1-carboxyvinyltransferase; Provisional.	2.36842e-166
NZ_CP047147.1|WP_003950755.1|5073638_5074361_-|M50-family-metallopeptidase	gnl|CDD|315961	pfam13398, Peptidase_M50B, Peptidase M50B-like. This is a family of bacterial and plant peptidases in the same family as MEROPS:M50B.	3.49482e-64
NZ_CP047147.1|WP_003950748.1|5067114_5067531_-|transcriptional-repressor	gnl|CDD|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	3.01371e-37
NZ_CP047147.1|WP_075986338.1|5074450_5075323_+|SOS-response-associated-peptidase	gnl|CDD|376837	pfam02586, SRAP, SOS response associated peptidase (SRAP). The SRAP family functions as a DNA-associated autoproteolytic switch that recruits diverse repair enzymes onto DNA damage. We propose that the human protein Q96FZ2:UniProtKB, the eukaryotic member of the SRAP family, which has been recently shown to bind specifically to DNA with 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxycytosine, is a sensor for these oxidized bases generated by the TET (tetrahedral aminopeptidase of the M42 family) enzymes from methylcytosine. Hence, its autoproteolytic activity might help it act as a switch that recruits DNA repair enzymes to remove these oxidized methylcytosine species as part of the DNA demethylation pathway downstream of the TET enzymes.	1.71418e-94
NZ_CP047147.1|WP_003950752.1|5070758_5071082_-|multidrug-efflux-SMR-transporter	gnl|CDD|224987	COG2076, EmrE, Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism].	1.53927e-27

Protein sequences

>NZ_CP047147.1|WP_010642418.1|5064846_5066580_+|sel1-repeat-family-protein
MEPADREDTDTGTAEDEVRRLGGAGAGDAASMSVIGAELLRRGDLDGAEPLLRGATAEGDRAAANNLGVLLHQRGYAEEAAGWWKVAAVAGSAAAAHALGRHHRERGDEPAAEYWLRQSAEQGHALGAYALADLLEHRREEGAERWMRAAAERGHREAAHRLARILDERGRTSEDAAHEAEQWYRQAAARGHRRAALRLGTILEGRGKLKEAGRWYLTSAKEGEPEAACALGFLLRDAGDEENAALWWLKAAKEGDGNAANALGALHAERGETQTAERWYRAALEAGDVNGAYNLGLLCAAQNRTAQADQWYRRAAYAGHREAANALAVLLLQENDADGAEPWFSKAAELGSVDAAFNLGILHAGRGDQRGAQRWYERAAAAGHTEAAFQAGIALLRDGDERGAERHLRCAAGGGSADGAYYLASLLDARTPPGEQPALGEPVLERTESEEWYERAAHLGHRRAQVRIGMIAATRGDVVSAARWYRAAAEAGSRNGAFNLGLLLAREGSEPEAAVWWEQAADAGHGRAALRLALLHARRGELAESDRWCGRAVELGPAEVAARAGRLRDQLQQELTA
>NZ_CP047147.1|WP_159313963.1|5061345_5064342_+|UPF0182-family-protein
MPDRGGGPTGPRIRVGRPSRRSRTLLMTLGVLAVLAMLFVMFAGFWTDWLWYKAVDYSSVFTTTLWTKIGLFFVFGLLMALAVGVNIWLAHRLRPPLSAMSLEQQSLDRYRMSIAPYKKWMLIGVTAVIGLISSASAAGQWRTWLLWINGVPFGEKDPQFGKDVAFYAFDLPWYRFLLGFGFAAAVLSLIAAALVHYLYGGLRVTSPGARATGAATGHLSVLLGLFVALKAVAYWLDRYGLAVKSSDFKAAGNWTGLRYVDANAYLPAKTILFCIAVICALLFFATLWRRTWQLPVIGFGLMVLSAILIGGLYPAIVQKFQVDPNEQAKEAPYVSQNLKATKKAYGIDDAKVTEYSGKAQTEDRTELRGEVAKAASIRLLDPNIVSPTFQQLQQMKGYYAFPQNLDVDRYKDADGNSRDTVIGLRELNLNGIPKNNWINDHFRYTHGFGVVAAEGTTADSEGRPVFTESDLPSKGDLVKGKYEQRIYYGERTEQYSIVGGPQKEIDYSDDDGEKTTSFSGKGGVDLSNPVNRAAYAVAFGEPQILYSGAIGEGSQVLYNRTPKDRVEAVAPWLTIDGDAYPAVVDGKIQWIVDAYTTSNGYPYSSRTTLGDTTADSLTAENQQRAVVAQENQVNYIRNSVKATVDAYDGTVKLYEWDTKDPVLKTWMKSFPGTVEPRGEISDELMDHLRYPQDLFKVQRELLTRYHVDNANTFLSGSQVWQVPDDPTNKSGESVPAYYLSMRMPDQEKQAFSLTTTFTPNNRDNLSAFMAVNAEADADDYGKIRVLKLPASTTVSGPKQVQSQFNSEQDIAESIRLLRGGDSEVEYGNLLTVPLDGGLLYVEPVYVRGGGLKYPLLRKVLVTYGGATAFEDTLGEALDKIFGTEGAEQPPGEQPEKPTDPPTGGNAVEDALKDAQKAYDEGQTALKEGDWEAYGKAQAELEKALEAMEKAAAEGGDGKNADKDPAESAGSEDARKEEQDGNGDKEAGKKPAEQAADRS
>NZ_CP047147.1|WP_003950745.1|5060604_5061165_-|hypothetical-protein
MSTHSPSGPPMAGSPLTRAVLEIDEYVAGLGWDRPALLFALVDTARLRSEEPGLADRLGIGEDVPDAAPLTPVEQEEIPAGKPLDEFLATIAWPDAVAGCALAVERLMLPPSAEAQVPDGLDDAALAKWVAAHPDRQEVRMTVGVLRDGTRDSALRLREKDASTEVLTGADLVPGLAEALAATFAE
>NZ_CP047147.1|WP_003950744.1|5059410_5060511_+|PDZ-domain-containing-protein
MPRRTATMLTSTLLLIALLCAGVLIKVPYAEMTPGPTVNTLGDHDGEPVLNIKGHKTYPTDGHLNMTTVRVTSPDYRMNLFQAVAGWIAHDNVVVPHETLYPDGKTEEQSTQENAEEFSQSQESAKVAALRELDIPVSTRVVVATVVKGNPAEGKLHAGDVIKSVDGSPVRKPGDVAELVTKHQPGEPVVFTIVPAADAAAAEKAGEEPSGTERVTVTTAPAGKSGGEAKRAIVGIQAGTDHTFPFTVDIKLADVGGPSAGLMFALGIVDKLSPDDLTGGKFIAGTGTIDEDGAVGPIGGISMKTVGARAKGAQYFLTPADNCATAAKDVPDGLTLVKVDTIDDALDSLEKIREDRTEALPACTTG
>NZ_CP047147.1|WP_008415685.1|5059127_5059385_+|hypothetical-protein
MAALAWLLIPLMAAIGAALWGSWAARNPGRNDGPELAGYARFRAAMAKSHGDPDAAESALPADLPATGEREQAHQPSDGPAPAVR
>NZ_CP047147.1|WP_010642425.1|5058457_5058940_+|molybdenum-cofactor-biosynthesis-protein-MoaE
MASTHTAHPERPDHPGERAAEDPIALLAVRDTPLSLDEVFKAVGEDAAGGTALFVGTVRNHDGGADVARLGYSAHPTAEAELRRVAERVVAAHPVRALAAVHRTGDLRVGEIAVIVAVSCPHRAEAFEACRMLIDDLKHEVPLWKHQTFGDGTEEWVGAC
>NZ_CP047147.1|WP_129845026.1|5057168_5058350_+|SDR-family-oxidoreductase
MTETSGPADPLPGGRKQPAGAFEAADTPKPAAERSARPVRGPVVAVTGAAGGVGALLTERLAASEEIKRVIAIDERRGECEGAEWQILDVRDPALAEKLRGVDVVVHLALDLDLESDPAARTAFNVRGTQTVLTAAPAAGVHRVVLCTSAMVYGALPDNELPLSEDAELRATAEATGVGDLLEIERLAKRAPRTHPGLNVTVVRPAVLVGGGADTALTRYFESPRLLVVADSRPAWQFCHVEDLCAALEYAVLERVEGDLAVGCDGWLEQEQVEELSGIRRMELPSAVALGAAARLHRIGLTPSPAGDLAYTMYPWVVSGSRLHHAGWRPKWTNEEVLGELLEEVAGRHTVAGRRLGRKDATVAGAAGAAGATVALLGTAAIVRRARKARRRI
>NZ_CP047147.1|WP_010642429.1|5055399_5056884_-|zinc-dependent-metalloprotease
MSDTPFGFGLPPEEPDDGDEGKKKDNQGGGAGQGANPLGFGMPGMPGIGPGGGDNPFAAMFGSLNPADLGAAFQQLGQMLSYEGGPVNWDMAKQIARQTVAQGTADGTKDASVGAAERHAVDEAVRLADHWLDGVTALPSGASTSVAWSRAEWVEATLPVWQELVDPVAERVGAAMGDVLPEEMKSMAGPLLGMMRSMGGAMFGTQMGQAVGTLAGEVVGSTDVGLPLGPAGKAALLPLNIEALGKDLGVPLEEVRLYLALREAAHQRLFAHVPWLRSHLFGAVEGYARGIDVDTAKLEDAVSQLDPSNPEQLQEALQQGMFQPEDTPQQKAALARLETALALVEGWVDAVVHEAAKPRLASADALRETLRRRRASGGPAEQTFATLIGLELRPRRLRDASRLWASLADARGADGRDALWEHPDMLPTAHDLDDPDGFVHREHADFSELDKLLGEAAGGPSLSKDRPEDAGEPGKKDKGSDDEGDGQEGGEGSR
>NZ_CP047147.1|WP_049977100.1|5054869_5055403_-|NUDIX-hydrolase
MTLHDDAVLVLKEYEDQPGLRQQYLDHLAAHPDGMYKPCEAGHLTASALVLDPSRGQVLLTLHRKLNMWLQMGGHCEPEDTSVARAALREATEESGIPGLELLPGGPVRLDRHAIPAPCNWHLDIQYAALAPAGAAAAISDESLDLRWFAYDEVAGVADASVVRLLEAARKRLGAPG
>NZ_CP047147.1|WP_010642433.1|5054053_5054806_+|AIM24-family-protein
MQSPLFAFTEQQSQDRYTLQNAQMLRVTLTGHDDILARKGAMVAYQGLVEFDGEYQSHQQQQARAWTGEGLDLMRCSGQGSVYFANLAQYVHVLDVEQDGLTVDSSYVLAMDSSLHAEVLAVDSQFGISGSGKYQLNITGRGKIALMTSGPPLMLQVTPEKYVNADADAIVAWSTSLRVQMQAQTHSSGVWRRRGSTGEGWELSFLGSGFALVQPSELLPPQNAATGGLAGQFGMGQQGARGQNQGNVWS
>NZ_CP047147.1|WP_003950748.1|5067114_5067531_-|transcriptional-repressor
MSDLLERLRGRGWRMTAQRRVVAEVLNGDHVHLTADEVHAKAIAKLPEISRATVYNTLGEMVTLGEVIEVATDGRAKRYDPNAHRPHHHLVCARCGAIRDVHPTGNPLADLPDQERFGFTVSEVEVTYRGLCPHCAAA
>NZ_CP047147.1|WP_003950749.1|5067678_5069130_+|catalase
MTQGPLTTEAGAPVADNQNSETAGVGGPVLVQDQLLLEKLAHFNRERIPERVVHARGAGAYGTFTVTADVTQWTRASFLSEVGKQTETFLRFSTVAGNLGAADAVRDPRGFALKFYTEDGNYDLVGNNTPVFFIKDAIKFPDFIHTQKRDPYTGSQEADNVWDFWGLSPESTHQVTWLFGDRGIPASYRHMNGYGSHTYQWNNEAGEVFWVKYHFKTDQGIKNLTTSEAAETSGLDPDSHQRDLREAIERGDFPSWTVQVQIMPAADAATYRFNPFDLTKVWPHEDYPPIEIGKLELNRNPENIFAEVEQSIFSPAHFVPGIGPSPDKMLQGRLFSYGDAHRYRVGINADHLPVNRPHATEARTNSRDGYLYDGRHKGAKNYEPNSFGGPAETGRALWQPLPVTGETGDTEAPSHAEDDNFVQAGNLYRLMSEDEKTRLVENLSQNIAGVSRDDIAERAINNFRQADADFGKRLEAAVQALRG
>NZ_CP047147.1|WP_003950750.1|5069225_5070032_-|histidinol-phosphatase
MADYHDDLRLAHVLADAADATTMERFKALDLKVETKPDLTPVTEADKAAEELIRGHLARARPRDAILGEEYGVEGTGPRRWVIDPIDGTKNYVRGVPVWATLISLMEADPQGGGFRPVVGLVSAPALGRRWWAAKGAGAYTGRSLTSASRLKVSAVDRVENASFAYSSLSGWEAQGRLDGFLDLTRTCWRTRGYGDFWPYMMVAEGSVDICAEPELSLWDMAANAVIVEEAGGTFTSLEGAPGPSGENAAASNGLLHDELLGYLNQRY
>NZ_CP047147.1|WP_018893589.1|5070175_5070793_+|TetR/AcrR-family-transcriptional-regulator
MSEVRAALLIAAEAHLARRPWSAVRMGEVAASAGVSRQTLYNEFGSKEGLARALARQAADGYLAGIERALARSAADPRERLRAAADWTVAAARPGTLLRSLLTGCWGDPLPAPRPARTTATAPAQRCAELPLPGPGDLLAAARDRAVAALDGAAPRTDPRELARECECVLRLALSRVVAPPVVGGAGAGRRRGRVTGPSPRAGGR
>NZ_CP047147.1|WP_003950752.1|5070758_5071082_-|multidrug-efflux-SMR-transporter
MAWLLVVVAGLLETGFAVCLKLSHGFTRLWPTIAFAAFALGSFGLLTLALKRLDVGPAYAVWTGIGAAGTATYGMIFLGDVVSVLKIVSITLVICGVIGLQLSGSAQ
>NZ_CP047147.1|WP_003950753.1|5071209_5072226_-|ribosome-small-subunit-dependent-GTPase-A
MRRYGKNPDEDDIRVRPSRRGSRPRTHTRPKHEDAAEGMVLTVDRGRITCLVEGRTVTAMKARELGRKAAVVGDRVALVGDLSGQKDTLARIVRIEERASVLRRTADDDDPYERVVVANADRLAIVTALADPEPRPRMIDRCLVAAYDGGLEPVLVLTKSDLASPDSLLDTYRALGVPYVVTSREELEDGSAVERVRELLDGHVTAFVGHSGVGKTTLVNALVPEEQRRVTGHVNAVTGRGRHTTVSALALPLADAAPGSWVIDTPGVRSFGLHHVDPSRVIHAFPDLEPGTEECPRGCSHDEPECALDQWVADGHADPARLNSLRRLLATRERREGD
>NZ_CP047147.1|WP_003950754.1|5072243_5073596_-|3-phosphoshikimate-1-carboxyvinyltransferase
MTLNPVSTPLWPAPYATGAVEATVQVPGSKSVTNRALVLAALAAEPGWLRRPLRSRDTVLMAEALRTLGVGIEETVSSDSAAPGSTLAKGGEAWRIIPSGLRGPATVDVGNAGTVMRFLPPLATLADGDIRFDGDPRSYERPLHGVIDALRALGARIDDDDRGSLPMTVHGTGSLDGGTVEIDASSSSQFVSALLLSAPRFNQGVEVRHIGPRLPSMPHIRMTVDMLRRVGAQVDEPESGGEPNVWRVTPGALLGRDLTVEPDLSNAQPFLAAALVTGGRVVVPDWPAHTTQPGDRLREIFTTMGGSCELTEAGLVFTGSGRVHGIDVDLGEVGELTPGIAAVAALADGESVLRGVAHLRLHETDRLAALTKEINELGGDVTETADGLRIRPRPLHGGVFHTYDDHRMATAGAILGLVVKGVEIENVATTAKTLPDFPDLWTGMLDGTGQ
>NZ_CP047147.1|WP_003950755.1|5073638_5074361_-|M50-family-metallopeptidase
MQSTTAAPATDLWDRVTGTQTAPEFWLVVATGVAALAVVLWGPAWRTARNAITIAHEGGHGLIALVTGRTLEGIRLHSDTSGLTVSRGRPTGPGMILTALAGYTAPSLLGLGGAWLLASGHITLLLWVATALLLALLVMVRNAYGVLTVLITGGLFVAVSWLAGSEVQALFAYAAVWFLLLGGVRPVFELQSKRRRGGAPDSDADQLARLTHAPAAIWLFLFHAVALCSLIGGGGWLLGR
>NZ_CP047147.1|WP_075986338.1|5074450_5075323_+|SOS-response-associated-peptidase
MCGRYAATRSPEDLSEIFGVEKTELSEAAEGQEDGHEAGASPVPTETLVPDWNVAPTKEVPAILDRPVKGSDDPRPVRQLRMLNWGLVPSWATSPDGGARMINARAETVHEKPAYRRAFASRRCILPADGYYEWVTAPEERKLEEEGKRKRARKQPYFVTPADGSVFAMAGLYEFWRDPSLPGDHPRAWWVTCSVLTTEAETAPLGVGPAEGPRALADIHPRMPLMLTPDKWDAWLDPSKTDVGEVRELLGAPPEGLMRAYPVATAVSNVRNNGPGLVSELDGPEVGTLF
>NZ_CP047147.1|WP_128825885.1|5075618_5076266_+|hydrolase
MPAAGERVTVATDVGEARVTWVRAEVPRVVLALGHGAGGGIEARDLVALAGVLPGAGVSVALVEQPWRVAGKKVAPAPKTLDKGWEAVWGEVAGEGLPVVAGGRSAGARVACRTGAELGAAGVLALSFPLHPPGKPERSRAGELLGTGVPTLVVQGGRDPFGRPEEFPGGSYELAEVAYGDHGFAVPKKAPVGQEEALGVITDAVGAWIERLPVG

Crispr_ID: NZ_CP047147_30

• CRISPR_ID: NZ_CP047147_30
• CRISPR_location: 5096687-5096782
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP047147_30

Consensus_repeat	Method
CAGCCCGGCCGGCGTTTGAGGCCATCTTGAA	CRISPRCasFinder

spacers of NZ_CP047147_30

>30.1|5096718|34|NZ_CP047147|CRISPRCasFinder
GCGGAACGGCTGAGGACGTAGCCCGGCCCAAATA

CRISPR arrays and Neighbor proteins around NZ_CP047147_30

CRISPR arrays

The CRISPR arrays of NZ_CP047147_30

>merge|NZ_CP047147|30|5096687-5096782|CRISPRCasFinder
CAGCCCGGCCGGCGTTTGAGGCCATCTTGAAGCGGAACGGCTGAGGACGTAGCCCGGCCCAAATACAGCCCGGCCGGCGCTTGAGGCCATCTTGAA

>NZ_CP047147|30|23|5096687-5096782|CRISPRCasFinder
CAGCCCGGCCGGCGTTTGAGGCCATCTTGAA	GCGGAACGGCTGAGGACGTAGCCCGGCCCAAATA
CAGCCCGGCCGGCGCTTGAGGCCATCTTGAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_026282227.1|5105322_5105916_-|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl|CDD|376556
NZ_CP047147.1|WP_086014580.1|5089433_5090138_-|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225099
NZ_CP047147.1|WP_003950772.1|5092902_5093802_+|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl|CDD|223472
NZ_CP047147.1|WP_008415740.1|5102371_5102632_-|UBP-type-zinc-finger-domain-containing-protein	unknown	unknown	gnl|CDD|366940
NZ_CP047147.1|WP_003950779.1|5099141_5100110_-|diacylglycerol-kinase	unknown	unknown	gnl|CDD|224513
NZ_CP047147.1|WP_030765450.1|5083466_5085842_-|ribonucleoside-diphosphate-reductase-subunit-alpha	unknown	unknown	gnl|CDD|274170
NZ_CP047147.1|WP_003950764.1|5082414_5083467_-|ribonucleotide-diphosphate-reductase-subunit-beta	unknown	unknown	gnl|CDD|153108
NZ_CP047147.1|WP_008415733.1|5096878_5098345_+|PAS-domain-containing-protein	unknown	unknown	gnl|CDD|378836
NZ_CP047147.1|WP_129844983.1|5104310_5105291_-|pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl|CDD|225313
NZ_CP047147.1|WP_003950771.1|5091898_5092906_+|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|224096
NZ_CP047147.1|WP_159313096.1|5100210_5100636_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159313097.1|5100645_5101509_-|SigB/SigF/SigG-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|274373
NZ_CP047147.1|WP_159313098.1|5102710_5104306_+|Na+/H+-antiporter	unknown	unknown	gnl|CDD|223104
NZ_CP047147.1|WP_008415722.1|5086710_5088933_-|carbon-starvation-protein-A	unknown	unknown	gnl|CDD|184976
NZ_CP047147.1|WP_003950773.1|5093807_5095301_+|glycoside-hydrolase-family-3-protein	unknown	unknown	gnl|CDD|224389
NZ_CP047147.1|WP_003950781.1|5101739_5102153_-|hypothetical-protein	unknown	unknown	gnl|CDD|235217
NZ_CP047147.1|WP_003950777.1|5098565_5098823_-|WhiB-family-transcriptional-regulator	unknown	unknown	gnl|CDD|376791
NZ_CP047147.1|WP_003950770.1|5090508_5091807_+|sugar-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270450
NZ_CP047147.1|WP_003950767.1|5086471_5086714_-|YbdD/YjiX-family-protein	unknown	unknown	gnl|CDD|377308
NZ_CP047147.1|WP_003950774.1|5095446_5096229_-|glucosamine-6-phosphate-deaminase	unknown	unknown	gnl|CDD|179028

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_026282227.1|5105322_5105916_-|N-acetylmuramoyl-L-alanine-amidase	gnl|CDD|376556	pfam01510, Amidase_2, N-acetylmuramoyl-L-alanine amidase. This family includes zinc amidases that have N-acetylmuramoyl-L-alanine amidase activity EC:3.5.1.28. This enzyme domain cleaves the amide bond between N-acetylmuramoyl and L-amino acids in bacterial cell walls (preferentially: D-lactyl-L-Ala). The structure is known for the bacteriophage T7 structure and shows that two of the conserved histidines are zinc binding.	5.25437e-21
NZ_CP047147.1|WP_086014580.1|5089433_5090138_-|GntR-family-transcriptional-regulator	gnl|CDD|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.50583e-73
NZ_CP047147.1|WP_003950772.1|5092902_5093802_+|carbohydrate-ABC-transporter-permease	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	1.25204e-83
NZ_CP047147.1|WP_008415740.1|5102371_5102632_-|UBP-type-zinc-finger-domain-containing-protein	gnl|CDD|366940	pfam02148, zf-UBP, Zn-finger in ubiquitin-hydrolases and other protein.	2.53227e-07
NZ_CP047147.1|WP_003950779.1|5099141_5100110_-|diacylglycerol-kinase	gnl|CDD|224513	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only].	3.41952e-42
NZ_CP047147.1|WP_030765450.1|5083466_5085842_-|ribonucleoside-diphosphate-reductase-subunit-alpha	gnl|CDD|274170	TIGR02506, Ribonucleoside-diphosphate_reductase_large_subunit, ribonucleoside-diphosphate reductase, alpha subunit. This model represents the alpha (large) chain of the class I ribonucleotide reductase (RNR). RNR's are responsible for the conversion of the ribose sugar of RNA into the deoxyribose sugar of DNA. This is the rate-limiting step of DNA biosynthesis. Class I RNR's generate the required radical (on tyrosine) via a "non-heme" iron cofactor which resides in the beta (small) subunit. The alpha subunit contains the catalytic and allosteric regulatory sites. The mechanism of this enzyme requires molecular oxygen. E. Coli contains two versions of this enzyme which are regulated independently (NrdAB and NrdEF, where NrdA and NrdE are the large chains). Most organisms contain only one, but the application of the gene symbols NrdA and NrdE are somewhat arbitrary. This model identifies RNR's in diverse clades of bacteria, eukaryotes as well as numerous DNA viruses and phage. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism].	0
NZ_CP047147.1|WP_003950764.1|5082414_5083467_-|ribonucleotide-diphosphate-reductase-subunit-beta	gnl|CDD|153108	cd01049, RNRR2, Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain. Ribonucleotide Reductase, R2/beta subunit (RNRR2) is a member of a broad superfamily of ferritin-like diiron-carboxylate proteins. The RNR protein catalyzes the conversion of ribonucleotides to deoxyribonucleotides and is found in all eukaryotes, many prokaryotes, several viruses, and few archaea. The catalytically active form of RNR is a proposed alpha2-beta2 tetramer. The homodimeric alpha subunit (R1) contains the active site and redox active cysteines as well as the allosteric binding sites. The beta subunit (R2) contains a diiron cluster that, in its reduced state, reacts with dioxygen to form a stable tyrosyl radical and a diiron(III) cluster. This essential tyrosyl radical is proposed to generate a thiyl radical, located on a cysteine residue in the R1 active site that initiates ribonucleotide reduction. The beta subunit is composed of 10-13 helices, the 8 longest helices form an alpha-helical bundle; some have 2 addition beta strands. Yeast is unique in that it assembles both homodimers and heterodimers of RNRR2. The yeast heterodimer, Y2Y4, contains R2 (Y2) and a R2 homolog (Y4) that lacks the diiron center and is proposed to only assist in cofactor assembly, and perhaps stabilize R1 (Y1) in its active conformation.	1.34201e-108
NZ_CP047147.1|WP_008415733.1|5096878_5098345_+|PAS-domain-containing-protein	gnl|CDD|378836	pfam12282, H_kinase_N, Signal transduction histidine kinase. This domain is found in bacteria. This domain is about 150 amino acids in length. This domain is found associated with pfam07568, pfam08448, pfam02518. This domain has a single completely conserved residue P that may be functionally important. This family is mostly annotated as a histidine kinase involved in signal transduction but there is little published evidence to support this.	6.35995e-63
NZ_CP047147.1|WP_129844983.1|5104310_5105291_-|pyridoxal-phosphate-dependent-enzyme	gnl|CDD|225313	COG2515, Acd, 1-aminocyclopropane-1-carboxylate deaminase [Amino acid transport and metabolism].	2.34795e-41
NZ_CP047147.1|WP_003950771.1|5091898_5092906_+|sugar-ABC-transporter-permease	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	1.24187e-60
NZ_CP047147.1|WP_159313097.1|5100645_5101509_-|SigB/SigF/SigG-family-RNA-polymerase-sigma-factor	gnl|CDD|274373	TIGR02980, SigBFG, RNA polymerase sigma-70 factor, sigma-B/F/G subfamily. This group of similar sigma-70 factors includes clades found in Bacilli (including the sporulation factors SigF:TIGR02885 and SigG:TIGR02850 as well as SigB:TIGR02941), and the high GC gram positive bacteria (Actinobacteria) where a variable number of them are found depending on the lineage.	7.21139e-127
NZ_CP047147.1|WP_159313098.1|5102710_5104306_+|Na+/H+-antiporter	gnl|CDD|223104	COG0025, NhaP, NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism].	8.10967e-77
NZ_CP047147.1|WP_008415722.1|5086710_5088933_-|carbon-starvation-protein-A	gnl|CDD|184976	PRK15015, PRK15015, carbon starvation protein CstA.	0
NZ_CP047147.1|WP_003950773.1|5093807_5095301_+|glycoside-hydrolase-family-3-protein	gnl|CDD|224389	COG1472, BglX, Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism].	2.29796e-74
NZ_CP047147.1|WP_003950781.1|5101739_5102153_-|hypothetical-protein	gnl|CDD|235217	PRK04069, PRK04069, serine-protein kinase RsbW; Provisional.	7.74906e-18
NZ_CP047147.1|WP_003950777.1|5098565_5098823_-|WhiB-family-transcriptional-regulator	gnl|CDD|376791	pfam02467, Whib, Transcription factor WhiB. WhiB is a putative transcription factor in Actinobacteria, required for differentiation and sporulation.	1.80007e-28
NZ_CP047147.1|WP_003950770.1|5090508_5091807_+|sugar-ABC-transporter-substrate-binding-protein	gnl|CDD|270450	cd14747, PBP2_MalE, Maltose-binding protein MalE; possesses type 2 periplasmic binding fold. This group includes the periplasmic maltose-binding component of an ABC transport system from the phytopathogen Xanthomonas citri and its related bacterial proteins. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	4.42611e-116
NZ_CP047147.1|WP_003950767.1|5086471_5086714_-|YbdD/YjiX-family-protein	gnl|CDD|377308	pfam04328, Sel_put, Selenoprotein, putative. This entry includes a group of putative selenoproteins from Proteobacteria, Actinobacteria and Firmicutes. The invariant cysteine at the C-terminus is encoded by a TGA Sec codon in some Epsilonproteobacteria, suggesting a redox activity for the protein.	4.50459e-19
NZ_CP047147.1|WP_003950774.1|5095446_5096229_-|glucosamine-6-phosphate-deaminase	gnl|CDD|179028	PRK00443, nagB, glucosamine-6-phosphate deaminase; Provisional.	1.24907e-131

Protein sequences

>NZ_CP047147.1|WP_003950774.1|5095446_5096229_-|glucosamine-6-phosphate-deaminase
MEVVIVPDARTGGELIADAIAALLRRKPDALLGVATGSTPLPVYQALAAKVADGAVDASRARICQLDEYVGLPPGHPESYRSVVLREVVEPLGLPASSFMGPDGSAEDVQAACEAYDAALGVAGGVDLQLLGIGTDGHIGFNEPCSSLASRTRIKTLTEQTRRDNARFFDSLDEVPHHVITQGIGTILDARHLVLLATGEGKAQAVADTVEGPVASVVPASALQLHPHATVVVDEAAASKLRLAPYFRDTYAAKPKWQGL
>NZ_CP047147.1|WP_003950773.1|5093807_5095301_+|glycoside-hydrolase-family-3-protein
MTAQPTTVSGDQLTRDALAVLQPGFTGTEAPEWLLRQIRDGLTSVGLFGRNITSPGQLSALTAQLRAEREDILVAIDEEGGDVTRLEVVDGSSVPGNHALGAVDDPELTRAVAHELARRLADCGVHLNWAPSADVNSDPDNPVIGVRSFGSDPDLVARHTAAYVEGMQSAGVAACTKHFPGHGDTAVDSHHALPTIGVGADVLAARDLTPFRAAIAAGSKAVMSAHILVPALDPDQPATLSRRILTGLLREELGYEGLIVTDGMEMQAISATYGIERGSVLAIAAGADAICVGGGLADEQTVIKLRDTLVAAVRSGELAEERLADAAARVRALAAWTTATPRATGERTPDIGLVAARRALEITRTEEHRALTGTPHVVSFAPVANIAVGDETPWGVAAELAARLPGTTSASYTEQDGAELAARVLAEAGERRLVAVVRDEHRHPWMARALDGLLAARPDTVVVEMGIPQSAPRGSLHVATHGASRVCGQAAAEAVTT
>NZ_CP047147.1|WP_003950772.1|5092902_5093802_+|carbohydrate-ABC-transporter-permease
MSTATQTPRTGTPAAEAPEPQVIRPDRKRTRLGYNIIALVTAAVMAFPVYWLIVSALRPNHEIRSYDQTLWPSSITFDNFARAVKQDNFVTAIQSSLIVSITAVVGGMIIATLAALAIGRFRFFGRRALLMVLILVQMLPPTAMLIPIYAQLNAMGGLDEYWGLIVVYLVSTLPFAVVMIRGFVVNIPVELEESAMVDGCTRMGAFRRVIFPLLAPGLAAASIFALVNAWNEYLFAYILINDNSKYTLNVWLMTFTTERGTDYGALMAASTMIALPVVIFFMIIQSKMAAGLTSGAVKG
>NZ_CP047147.1|WP_003950771.1|5091898_5092906_+|sugar-ABC-transporter-permease
MTAAETQAADPPAAIPSAPLDKGTPPPAGTPSNSGPPRRKKGALLPYLLILPAIIAVAAVYAFPLVKSVIMSFQDMGRRELWSGNTPPWVGFDQYTAILADSEFWYVVGRTVLFMAVCVTLTMAIGLLLALLMMRLTTWVRIVLTVALIAAWSMPLMVAASIFRWLSDSDYGLINTLIAKVAGEDFLGHNWFLNPWQGFGIITALVVWGAIPFVVVTLYAALTQVPKELEEAAALDGASATGIFRFVTWPVIKPVFVMVTTLSVIWDFNVFGQIWLLRGNKPEPEYETLGLYSFSKAFSSTSFSQGTAIALITVVLLSGVAVYYLRQLMKTGEVE
>NZ_CP047147.1|WP_003950770.1|5090508_5091807_+|sugar-ABC-transporter-substrate-binding-protein
MKRKLIAAIGVAGMMAGLAACGDSETASNAKPEDRKENLTVWLMVDAQSTWPELVKDVNAQFKKKYPNVKVNVQYQGWADKAKKLDTALGGDKFPDVVELGNTETMQYILNGALAEIDPKKYENSDTWIQGLTDTCTFEGKQYCVPYYAGARVAVYNQEMLKKATGSDALPETEDAFLKAMDKVSKEYGEKDKRYSSLYLPGRYWYAAMSYVAAYGGQIAEYDEGSKEWKGTLSSPESQKGIQHFVDLVKKYNKADLTKDEQDHANVMANEKAGVIYGNGWEAGSVVDGKNNGNAKLEGKIATAGMPGPEGKALPSFIGGSDLGIVEKSKAKDLAEEWVSLFTNEKSMEVLASKNILPNNTKQLEPLKEKPETAAVANAVPDAWFTPIAPGWTSIEKEEVLKNMLLQIIKGDSVEKAAKAADAKIDELINKG
>NZ_CP047147.1|WP_086014580.1|5089433_5090138_-|GntR-family-transcriptional-regulator
MPKYYRLKRHLLDMTRTLPPGTSVPPERTLAAEFDTSRTTVRQALQELVVEGRLERIQGKGTFVAKPKVSQALQLTSYTEDMRAQGLEPTSQLLEVGYITADDSLASLLDITAGGRVLRIERLRLASGEPMAIETTHLSAKRFPALRRSLVKYTSLYTALYEVYGVRPAEAEETIETSLATPREAALLATDVGLPMLMLSRHSRDESGAPVEWVRSVYRGDRYKFLARLKRPVE
>NZ_CP047147.1|WP_008415722.1|5086710_5088933_-|carbon-starvation-protein-A
MAEPAPPASGNRKLSAKSIAVWSLVAVVGAIAWSVLALSRGEEISAIWMLAAALGSYAIAYRFYSRFIANKVLKVDKNRATPAERLDNGVDFQPTDRRVLFGHHFAAIAGAGPLVGPILAAQMGYLPGTIWIVAGVIFAGAVQDMVTLFFSTRRNGRSLGQMARDEIGPVGGVAALIAVFMIMIILLAVLALVIVNALAGSPWGVFSIGMTIPIALFMGVYLRTLRPGKVTEVSVLGVALLLLAIVGGGWVAESSMADFFTLEPGTLVIWMVVYGFFASVLPVWMLLAPRDYLSTFMKVGTIVLMAVCVIIAMPTLKMDGVTSFATSGAGPVFSGSLFPFVFITIACGALSGFHSLVSSGTTPKMVQKETQIRMIGYGAMLTESFVAIMAMIAACIIDPGLYFAINSPAGVLGDTVQSASEAVANLGFTISPDQLAQAAKDVEEASLLSRTGGAPTFALGMAEIFAAALGGAGMKAFWYHFAIMFEALFILTTVDAGTRVGRFMLQDTLGNVWKPMRRVSWWPGVWLTSAIVVGCWGYFLWVGVHDPLGGINQLFPLFGIANQLLAAVALAVCTTLLIKSGRLKWAWVTGIPLAWDVAVTLTASWQKVFSDNPAIGFFAQRAKYQDGIDAGEVLAPAKSMSDMHTVVTNSTVDGVLSIVFAVLIIIVLVDAGRVSYNAIRKPESVKLAEAPFEQSKIVAPAGMFATSEEKAELALVGAGAPASAGDGDGDAPAKQGGGQA
>NZ_CP047147.1|WP_003950767.1|5086471_5086714_-|YbdD/YjiX-family-protein
MSGEAAHHPGRLGVLAHRVRAGVRWIGWYVREVSGETAYEKYAAHVRRHDPDAEVMTRRQFERSRMDAREADPRDGFRCC
>NZ_CP047147.1|WP_030765450.1|5083466_5085842_-|ribonucleoside-diphosphate-reductase-subunit-alpha
MTIAPADPSTAEVRAEEIQGPGGALLRTLTDLTADLPDTDPGRVAAAALRGRNAASDEAELRSLATEAAAGLISEDPAYSRLAARLLTRTIAEEAAGQGVTTFTESVATGHREGLIADRTAAFVTAHAERLDALVDPAADDRFGYFGLRTVHSRYLLRHPHTRQVIETPQHFMLRVACGLAEDDSVRALDEVASLYRLMSALSYLPSSPTLFNSGTRHPQMSSCYLLDSPKDELESIYDRYHQVARLSKHAGGIGLAYSRIRARGSLIRGTNGHSNGIVPFLNTLDASVAAVNQGGRRKGAAAVYLETWHADVEEFLELRDNTGEEARRTHNLNLAHWIPDEFMRRVDADADWSLFSPSDVPELTDLWGDAFDAAYRAAEARGLARRTIPARELYGRMMRTLAQTGNGWMTFKDASNRTANQTALPGHTVHSSNLCTEILEVTDDGETAVCNLGSVNLGAFVDGGAIDWERLDEAVRTAVVFLDRVVDINFYPTEQAERSNSRWRPVGLGAMGLQDVFFQLRLPFDSPEAQRLSTRIAERIMLTAYETSCDLAEKNGPLPNWDRTRTAQGVLHPDHYDTDLAWPERWEALRARVAESGMRNALLLAIAPTATIASIAGVYECIEPQVSNLFKRETLSGEFLQVNSYLVEDLKRLGVWDARTREALREASGSVQGFAWIPEELRALYRTAWELPQRGLIDMAAARTPFLDQSQSLNLFMETPTIGKLSSMYAYAWKKGLKTTYYLRSRPATRIARAAGGSAPATATVPAQAAPDAEAIACSLENPESCEACQ
>NZ_CP047147.1|WP_003950764.1|5082414_5083467_-|ribonucleotide-diphosphate-reductase-subunit-beta
MTTPDTTPAANAHTVGAAKNLLDPGFELTLRPMRYPDFYERYRDAIKNTWTVEEVDLHSDVADLAKLSPGEQHLIGRLVAFFATGDSIVANNLVLTLYKHINSPEARLYLSRQLFEEAVHVQFYLTLLDTYLPDPADRADAFAAVENIPSIREKAEFCFRWMDSVDKLDQLESQADRRKFLLNLICFAACIEGLFFYGAFAYVYWFRSRGLLHGLATGTNWVFRDETMHMSFAFDVVDTVRKEEPELFDDKLQEQVVAMLKEAVEAELQFARDLCGDGLPGMNTESMREYLECVADQRLTRLGFAPVYGSQNPFSFMELQGVQELTNFFERRVSAYQVAVEGTVSFDDDF
>NZ_CP047147.1|WP_008415733.1|5096878_5098345_+|PAS-domain-containing-protein
MNELVRQHTALGDTDLEWLHLLVSEWQLLSDLSFADLILWVPTRDGTRYVSVAQMRPNTGPTSYQNDMVGHLVPRGRRPMLDLALDEGRIVREGDPEWREEVPVRVESIPVCREGRILGVIARNTNLLTVRTPSRLELTYLQSASDLAQMIAAGSFPFADQQGDTDVSPRAGDGLIRLDADGIVQYASPNALSAYHRLGLAADLVGHHLGQTTTELAPARGAVDEAMVKLASGWAPREAEVEGSDGVIQLRAIPLRPKGTHIGSLVLLRDVTELRRRERELMTKDATIREIHHRVKNNLQTVAALLRLQARRIDSERGREALVEAVRRVGSIAIVHETLSQNLDERVEFDEIADRVLAMVAEISPGRVEGRRSGRFGILDAEVATPLSMVLTEVLQNALEHGFRPGDTGEVEVSAVRGGTRKDARLLITVQDNGVGLPEGFDAHTAGNLGLQIVRTLVEGELGGTFDMNSAPEGGTRVLLDIPVRGDL
>NZ_CP047147.1|WP_003950777.1|5098565_5098823_-|WhiB-family-transcriptional-regulator
MDWRHNAVCREEDPELFFPIGNTGPALLQIEEAKAVCRRCPVAEQCLQWALESGQDSGVWGGLSEDERRAMKRRAARNRARNASA
>NZ_CP047147.1|WP_003950779.1|5099141_5100110_-|diacylglycerol-kinase
MRALLVVNPAATTTSARTRDVLIHALASEVKLEAVTTEYRGHARDIGRLAAASSDVDMVVALGGDGTVNEVVNGLLHDGPDPDRLPGLAVVPGGSTNVFARALGLPNDPVEATGALLDALRTGSQRTVSLGLASGTPGSEDEAVPGRWFTFTAGLGFDAGVIGRVEQHRERGRRSTHPLYVRQVLRQFVGEPHRRHGLITLEQPGQEPVDDLVLSVVCNTAPWTYLGNRPIYASPRASFDTGLDIFGLSRLSTMAVARYGTQLLASSPERGPRGRHALSRHDLTEFTLHSKAPLPFQMDGDHLGLRTSVTFAGVRRALRVIV
>NZ_CP047147.1|WP_159313096.1|5100210_5100636_+|hypothetical-protein
MSTEQTPTDPGPRPTRLTVVAVLAAVEGLALVVVGLVLAVRALLGDGELRSALTGGLTLVALGVIPLAAARGLLARRSWSRGPAIITQILALPVAWQFLQADSVLIPGGVVLAVVAISALVMLVNPATTIDLGIRPPGAER
>NZ_CP047147.1|WP_159313097.1|5100645_5101509_-|SigB/SigF/SigG-family-RNA-polymerase-sigma-factor
MTEDKHQDEKSGGQDEQPEHQKDQAPPAGAPVDRPDPHDRSGARALFIELRTLPAGGPEYAELRNRLVRMHLPLVEHLARRFRNRGEPLDDLTQVATIGLIKSVDRFDPERGVEFSTYATPTVVGEIKRHFRDKGWAVRVPRRLQELRLSLTSATAELSQRHGRSPTVHELAEKLGISEEEVLEGLESANAYSTLSLDVPDTDDESPAVADTLGSEDEALEGVEYRESLKPLLEDLPPREKRILLLRFFGNMTQSQIAQEVGISQMHVSRLLARTLAQLREKLLVEE
>NZ_CP047147.1|WP_003950781.1|5101739_5102153_-|hypothetical-protein
MSPIAGEPGTQDFVEVRLPAAGAYLSVLRTATAGLAARLDFTLDEIEDLRIAVDEACAILLQQAVPGSVLGCVFRLIDDSLEVTVSAPTTDGKAPERDTFAWTVLSALAGKVDSSVAEDNTVSISLHKQRGAGPGPA
>NZ_CP047147.1|WP_008415740.1|5102371_5102632_-|UBP-type-zinc-finger-domain-containing-protein
MNKCTHVTELPHPEPAPSADTCLECLEVGSNPVQLRKCLYCGHVACCDSSPYRHATAHFRESGHPVMRSAEPGESWRWCYADGSIV
>NZ_CP047147.1|WP_159313098.1|5102710_5104306_+|Na+/H+-antiporter
MDVLPLLLLVAGSTAVAGAARRTAVPAPLILVTAGLLVSYIPGVPAYTLDPEIVLPLVLPPLLHTAAMDSSYLDLRAQLRSVALLSVGYTLFATLVVGWAVHLIVPDLPLTAALVLGAVVAPPDAVAATAVARRVGLPSRITTILQGESLVNDATAITAYRVAVAAAIGESAGLLHAGTEFLVASLGGVAVGLVLMVPLHWLRTHLREPLLKNTLSLLIPFAAYALAEYAGASGVLAVVVVALYLGHHSWQVDFATRLQEDAVWKMVAFVLESAVFALIGLQLPLVVGGLGDYHVGEVLWYALAVFLVVVATRFVWTYPAVFLPRLVSRRIRAREPDPTWKGPFVVAWAGMRGVVSLAIAFSIPHAVHEGGPFPYRNLILFLTFTTVIGTLVVQGLTLPALIRLLRLPGRDVRAETLLEAQAQNAASEAAERRLDALLDDPSNALPQPLADRLRSVLERRRNAVWERLGTVNPQTGESVDDTYRRLARSMIASEREVFVALRDRRHIDDEMLRDLLRRLDLEEAAAYREEG
>NZ_CP047147.1|WP_129844983.1|5104310_5105291_-|pyridoxal-phosphate-dependent-enzyme
MSAHPDPVPPVPEPSVPRARDGRAHREPVRPLLPSPVQELREPAFERYGVRLLLKRDDLIHPDIPGNKWRKLAPVLREADGRTVVTFGGAWSNHLRATAAAGRLLGFPTVGVVRGEELAGRPLNPSLARCRADGMRLAFVSRSRYRLRGDAAVRDALVAEAAGPGLPVRVVPEGGSDAAAVRACAVLGEELAVLRESVPAVAVACGTGGTLAGLAAGLAPEQEAVGVAVLKGGFLGAGVAAHQRAAFGGERGRWTVEDGFHHGGYARTTPELEEFATAFEQRHGLGVERVYVAKLLHGLAALAADGRFRRGTALAAVVTGRPFPEA
>NZ_CP047147.1|WP_026282227.1|5105322_5105916_-|N-acetylmuramoyl-L-alanine-amidase
MAPPMSADRFLKALKDEGVTVVEVGSWRSHNRNSKGAWGPVNGVMIHHTVTSGSARTVDICRNGYSGLPGPLCHGVITKDGRVHLVGYGRANHAGLGDDDVLAAVIAERASYPPVNEANTDGNARFYGFECENLGDGKDPWTSAQLDAIERVSAAICRVHGWNQQSVIGHLEWQPGKIDPRGFTMKSMRERIKGRLK

Crispr_ID: NZ_CP047147_31

• CRISPR_ID: NZ_CP047147_31
• CRISPR_location: 5236710-5236797
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP047147_31

Consensus_repeat	Method
TGGCCTCAAGCGCCGGCCGGGCTG	CRISPRCasFinder

spacers of NZ_CP047147_31

>31.1|5236734|40|NZ_CP047147|CRISPRCasFinder
ATCGAGGGGTGCTGGTCTGTGCCGACCTCGCGGTCAAGGA

CRISPR arrays and Neighbor proteins around NZ_CP047147_31

CRISPR arrays

The CRISPR arrays of NZ_CP047147_31

>merge|NZ_CP047147|31|5236710-5236797|CRISPRCasFinder
TGGCCTCAAGCGCCGGCCGGGCTGATCGAGGGGTGCTGGTCTGTGCCGACCTCGCGGTCAAGGATGGCCTCAAGCGCCGGCCGGGCTG

>NZ_CP047147|31|24|5236710-5236797|CRISPRCasFinder
TGGCCTCAAGCGCCGGCCGGGCTG	ATCGAGGGGTGCTGGTCTGTGCCGACCTCGCGGTCAAGGA
TGGCCTCAAGCGCCGGCCGGGCTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_159313128.1|5233019_5234054_-|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|366009
NZ_CP047147.1|WP_018470815.1|5228988_5231406_+|ATP-binding-protein	unknown	unknown	gnl|CDD|223021
NZ_CP047147.1|WP_008409337.1|5234671_5235508_-|ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|372253
NZ_CP047147.1|WP_003950904.1|5238848_5239787_-|cellulose-binding-protein	unknown	unknown	gnl|CDD|224117
NZ_CP047147.1|WP_159313132.1|5247100_5247946_-|hypothetical-protein	unknown	unknown	gnl|CDD|225596
NZ_CP047147.1|WP_003950908.1|5245995_5246985_+|methylmalonyl-Co-A-mutase-associated-GTPase-MeaB	unknown	unknown	gnl|CDD|224617
NZ_CP047147.1|WP_003950896.1|5232532_5232925_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_003950892.1|5227086_5227935_+|3-hydroxyacyl-CoA-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|224170
NZ_CP047147.1|WP_003950891.1|5226333_5226906_-|cob(I)yrinic-acid-a,c-diamide-adenosyltransferase	unknown	unknown	gnl|CDD|376665
NZ_CP047147.1|WP_008407901.1|5248902_5249568_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NZ_CP047147.1|WP_159313129.1|5235504_5236587_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|213235
NZ_CP047147.1|WP_003950893.1|5228342_5228666_+|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132914
NZ_CP047147.1|WP_003950899.1|5234312_5234654_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159313130.1|5237704_5238724_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|213235
NZ_CP047147.1|WP_003950906.1|5244120_5244561_-|methylmalonyl-CoA-epimerase	unknown	unknown	gnl|CDD|213772
NZ_CP047147.1|WP_010642212.1|5236932_5237703_-|ABC-transporter-permease-subunit	unknown	unknown	unknown
NZ_CP047147.1|WP_026282219.1|5244704_5245907_+|acetyl-CoA-C-acetyltransferase	unknown	unknown	gnl|CDD|180261
NZ_CP047147.1|WP_010642200.1|5248101_5248782_-|PepSY-domain-containing-protein	unknown	unknown	gnl|CDD|377032
NZ_CP047147.1|WP_159313131.1|5240047_5243911_-|hypothetical-protein	unknown	unknown	gnl|CDD|173412
NZ_CP047147.1|WP_086014554.1|5231657_5232359_-|endonuclease-NucS	unknown	unknown	gnl|CDD|235114

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_159313128.1|5233019_5234054_-|LLM-class-flavin-dependent-oxidoreductase	gnl|CDD|366009	pfam00296, Bac_luciferase, Luciferase-like monooxygenase.	1.03421e-49
NZ_CP047147.1|WP_018470815.1|5228988_5231406_+|ATP-binding-protein	gnl|CDD|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	3.22534e-06
NZ_CP047147.1|WP_086014554.1|5231657_5232359_-|endonuclease-NucS	gnl|CDD|235114	PRK03298, PRK03298, endonuclease NucS.	1.188e-176
NZ_CP047147.1|WP_003950904.1|5238848_5239787_-|cellulose-binding-protein	gnl|CDD|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	1.2649e-06
NZ_CP047147.1|WP_159313132.1|5247100_5247946_-|hypothetical-protein	gnl|CDD|225596	COG3054, COG3054, Predicted transcriptional regulator [General function prediction only].	0.00838398
NZ_CP047147.1|WP_003950908.1|5245995_5246985_+|methylmalonyl-Co-A-mutase-associated-GTPase-MeaB	gnl|CDD|224617	COG1703, ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family [Amino acid transport and metabolism].	1.18363e-121
NZ_CP047147.1|WP_003950892.1|5227086_5227935_+|3-hydroxyacyl-CoA-dehydrogenase-family-protein	gnl|CDD|224170	COG1250, FadB, 3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism].	2.18027e-125
NZ_CP047147.1|WP_026282219.1|5244704_5245907_+|acetyl-CoA-C-acetyltransferase	gnl|CDD|180261	PRK05790, PRK05790, putative acyltransferase; Provisional.	0
NZ_CP047147.1|WP_008407901.1|5248902_5249568_+|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	4.92636e-85
NZ_CP047147.1|WP_159313129.1|5235504_5236587_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|213235	cd03268, ABC_BcrA_bacitracin_resist, ATP-binding cassette domain of the bacitracin-resistance transporter. The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.	1.17964e-91
NZ_CP047147.1|WP_003950893.1|5228342_5228666_+|STAS-domain-containing-protein	gnl|CDD|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	3.80542e-20
NZ_CP047147.1|WP_003950891.1|5226333_5226906_-|cob(I)yrinic-acid-a,c-diamide-adenosyltransferase	gnl|CDD|376665	pfam01923, Cob_adeno_trans, Cobalamin adenosyltransferase. Cobalamin adenosyltransferase This family contains the gene products of PduO and EutT which are both cobalamin adenosyltransferases. PduO is a protein with ATP:cob(I)alamin adenosyltransferase activity. The main role of this protein is the conversion of inactive cobalamins to AdoCbl for 1,2-propanediol degradation.The EutT enzyme appears to be an adenosyl transferase, converting CNB12 to AdoB12.	4.10908e-79
NZ_CP047147.1|WP_159313130.1|5237704_5238724_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|213235	cd03268, ABC_BcrA_bacitracin_resist, ATP-binding cassette domain of the bacitracin-resistance transporter. The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.	1.09128e-89
NZ_CP047147.1|WP_003950906.1|5244120_5244561_-|methylmalonyl-CoA-epimerase	gnl|CDD|213772	TIGR03081, Methylmalonyl-CoA_epimerase_mitochondrial, methylmalonyl-CoA epimerase. Members of this protein family are the enzyme methylmalonyl-CoA epimerase (EC 5.1.99.1), also called methylmalonyl-CoA racemase. This enzyme converts (2R)-methylmalonyl-CoA to (2S)-methylmalonyl-CoA, which is then a substrate for methylmalonyl-CoA mutase (TIGR00642). It is known in bacteria, archaea, and as a mitochondrial protein in animals. It is closely related to lactoylglutathione lyase (TIGR00068), which is also called glyoxylase I, and is also a homodimer.	7.337e-51
NZ_CP047147.1|WP_010642200.1|5248101_5248782_-|PepSY-domain-containing-protein	gnl|CDD|377032	pfam03413, PepSY, Peptidase propeptide and YPEB domain. This region is likely to have an protease inhibitory function (personal obs:C Yeats). This model is likely to miss some members of this family as the separation from signal to noise is not clear. The name is derived from Peptidase & Bacillus subtilis YPEB.	2.51816e-07
NZ_CP047147.1|WP_159313131.1|5240047_5243911_-|hypothetical-protein	gnl|CDD|173412	PTZ00121, PTZ00121, MAEBL; Provisional.	3.0205e-22
NZ_CP047147.1|WP_008409337.1|5234671_5235508_-|ABC-transporter-permease-subunit	gnl|CDD|372253	pfam12679, ABC2_membrane_2, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family.	2.32431e-05

Protein sequences

>NZ_CP047147.1|WP_159313129.1|5235504_5236587_-|ATP-binding-cassette-domain-containing-protein
MIEATGLTKRYGAKTAVHDLSFQVRPGTVTGFLGPNGSGKSTTMRMIVGLDEPTSGHVTIGGLPYRRVPNAPRQVGALLDAKAVHGGRSARNHLLCLAQLSGIPARRVDEVLGVVGLQDVARHRSKGFSLGMGQRLGIAAALLGDPQVLLFDEPVNGLDPEGILWVRTLMKSLAAEGRTVFVSSHLMSEMALTAEHLIVIGRGRLMADMSVREFIAANAAGFARVRVPDTEPGSREKLAAALAEEGGQVLPEPDGALRVAGLPLPRISDVAHTAGVRLWELSPHQASLEEAYMRLTQGAVDYRSTDDRRAGLHEEGAQGPEPFPVPQPGADQPGWYAPPPPRQERPAAPDLSKSETEDPR
>NZ_CP047147.1|WP_008409337.1|5234671_5235508_-|ABC-transporter-permease-subunit
MTTPTQQPEQPGALPGAMYTSPIPVRPTHLGHALASEWTKIRSVRSTVWTLCVFVALVVGIGLLVGWKTSGETYTDVPYTIPALFGLMLGQICLITLGVLVVTSEYGTGMIRTTFTAAPQRHRVLAAKFLVFFALAYTVSAVSITVVGLATAAINEIPSGPGENWGTSVLLGSLYVSLLGVLGLAVGSMLRHSAGAITAMLGVVLVPAIMPAFLMISPALRGIGETMLEYNAPNSLSALFGTAMYDGQAGGVPQLLALLGITLVAVAGAFALLEKRDV
>NZ_CP047147.1|WP_003950899.1|5234312_5234654_+|hypothetical-protein
MSPRKNRSKPSRSSGRRGGGDDEPGERYGFQSAESWRGEQWSVRHISGSGPASAGKRYRCPGCDQEIPAGLPHVVAWPEHSGVDERRHWHKACWNAKDRRTTRVQRSRNAPRF
>NZ_CP047147.1|WP_159313128.1|5233019_5234054_-|LLM-class-flavin-dependent-oxidoreductase
MHVGSFVLGGQFPGQGQGEALHRAVRSAEVAEEAGLDTVWLGEHHFVPYGTCPSATTLAALLLGRTRRVRVGTAVSVLPTTHPVALGEQAALLHLAAGGRFTLGVGRGGPWVDLEVFGAGLPAFEEGFPEALDLLLRWLREPRVGASAEGGRYAFREVAVVPSPAESLDGLPGPEVVVACTSPSSVRLAAERGLPMLLGMHTGDAEKAEMVALWRRHAREAGRDGDEIAAAAHVSAGVAQVEDGPGRATETLVKAMPGWFELGLGAHITVDGRARAMRDPVAYTEFLCSIHPVGPPRLCADRLAATAEATGITRFALMVEGSGDLAGTEENIRRLGRDVLPLLR
>NZ_CP047147.1|WP_003950896.1|5232532_5232925_+|hypothetical-protein
MSLDVSPALLEQAERGEVDEAAFVDCVRTSLPYAWDMISKLVAQLKVDGGEFADNQTPPPDEQARGQLLRALASDAIRGALQRHFGVRLAFQNCHRVAVFPLSSDSDERHARFTSIRGQLLNQSPELRDC
>NZ_CP047147.1|WP_086014554.1|5231657_5232359_-|endonuclease-NucS
MASGAARRVALPTMRLVIARCSVDYAGRLTAHLPSAPRLILVKADGSVSIHADDRAYKPLNWMSPPCTLKEGEDNVWTVVNKGGEKLVITMEEVLHDSSHELGVDPGLIKDGVEAHLQELLADRIETLGEGYTLIRREYPTAIGPVDILCRDASGATVAVEIKRRGEIDGVEQLTRYLELLNRDPHLAPVRGVFAAQEIKPQARVLATDRGIGCTVLDYNALRGIEDDKLRLF
>NZ_CP047147.1|WP_018470815.1|5228988_5231406_+|ATP-binding-protein
MDPNHRDPHQRGDGDPHRIPGGPQPGAVERRPRPPQGPDLGQPVPPRVRTAELVAGGHLVTVNPVDGSEIEVCPPGRHPSPPVRRTPDDRAALAAAARPPAPPGVPRTHHRLLERDRERDTLVQLLARGRSVRLTGSRGSGRTVLLDAVAARCEGLAPDGVVRLDGHHRTADELLHALCAAVHLLPAHRPGPALLAELAGEIGAVVLIDDAEIGGAALDSFLAATPECAVLLACTPEVPAPGEEARVEEVVLDGIGRSGGLTLLAQGAGRALSDDEVSWAGDLWFESEGLPLRFVQAGALLHQRDLLREESGSAEAPLPTVAEGAAPAALLASRLSEAARATLGFAYALGGEVPHQAHLPALVGDTHADAALTELLDCGLVTPVGNRYRLAAGVTEQLAAEGYADEGERAHTAAQHYTWWTGHPSVTPERAAAESDAVLAALTALVGGQDPARQATAVLLARTVAPVLAAGLAWGAWERVLRSGQEAARLSGEVAEEAYFHHELGILALCQDRLDRARAELEAAVALRGALADKRGTVAGRRALALVADRAGETVPVTRAVLPTDGPPVPPRRDGLGTPPTGFPRTTPAAGVTRVQPAASATGATVVGGPAATAAKDGRPGRAAVTGARRNLVAAGAGALLVAVLGTVVTLGAINGDDEEPASVDRVTTEQTTPEDEGDEGTEAERPADSAEPSTDPGEDGVTGTPDDPTPSDSGSPSESESDEPSSSPTDRPTTSPSDRPTTKPPTTPPTSSKPPTTPPPSSPDPEPSDTTPPTEDPDPEDPEPGTDNSASGPAPEPSTSQTLS
>NZ_CP047147.1|WP_003950893.1|5228342_5228666_+|STAS-domain-containing-protein
MYIRGDHAELVVGGRLDVRSAADARTVLHSAVDDGAGDLVLDLAALDSWDATGLGVIMGAHRRAGRCGRRLVLRSVPPQMQRLLVATRLHRILAIEGGIGLDSLPRA
>NZ_CP047147.1|WP_003950892.1|5227086_5227935_+|3-hydroxyacyl-CoA-dehydrogenase-family-protein
MARKLAVIGAGLMGSGIAQVSAQAGWDVVLRDVTDAALTRGTDGIKSSFDRFVAKGKLSAEDAGAALGRITTTTDLEGAADADIVVEAVFEQLDVKHEIFRTLDKLVREDTVLASNTSAIPITKIAAVTERPERVVGAHFFSPVPMMQLCELVRGYKTSDETLARTREFAESTGKTCIVVNRDVAGFVTTRLISALVVEAAKLYESGVATAEDIDLACKLGFGHAMGPLTTADLTGVDILLHATQNIYTESQDEKFAPPELMRRMVDAGDLGRKSGEGFYSY
>NZ_CP047147.1|WP_003950891.1|5226333_5226906_-|cob(I)yrinic-acid-a,c-diamide-adenosyltransferase
MVNLTRIYTRTGDKGTTALGDMSRTAKTDPRIAAYADANEANAAIGTALALGDLPEDIAKVLLRVQNDLFDVGADLSTPVVENPEYPPLRVEQSYIDKLEADCDTYLEQVEKLRSFILPGGTPGAALLHQACTVVRRAERSTWAAAEVFGDTMNPLAATYLNRLSDLLFILARVANKEVGDVLWVPGGER
>NZ_CP047147.1|WP_010642212.1|5236932_5237703_-|ABC-transporter-permease-subunit
MAVTQVVRSEWTKIRSVQSTVWTLGLAAVVTIGLGALISALSKSEYENLSPRDQLTFDPTFISFAGLSLGQLAMVVFGVLVVSNEYSTGMIRMSLAAVPQRGTFFFSKVAVATVLALLVSLVTTFATFFLGQALLGNLSASIGDPGVLRAVIGAALYMTLMAVFSMGVAAMLRSPMLSLGILVPFFFLVSSILGAVSATEKIGRFLPDQAGSKIMQVVAPLNDDTPYGPWGGLGIMALWVIAALAIGYALLRHRDA
>NZ_CP047147.1|WP_159313130.1|5237704_5238724_-|ATP-binding-cassette-domain-containing-protein
MIELSGLTKRYGERVAVNNLTFTVRPGIVTGFLGPNGAGKSTTMRMILGLDRPSAGDVRIDGRHYAQLHDPLRQIGALLDAKAMHGGRTAYNHLLCLAQSNGIPASRVTEVLDTVGLTPVARKRAKGFSLGMGQRLGIAGALLGDPRILMFDEPVNGLDPEGIHWIRNLMKSLAHQGRTVFVSSHLMSEMALTAEHLVVIGQGRLMADTSMADFIRENSRSYVTMRSPERERLLDVLHAAGIAVADGPDGAVEVDGVAAPELGELAARERLVLHELSPRQASLEEAFMQLTAESVEYHAHDGDPGAVRGGPAPGGGATSGGEDQWGAGWGGPEQRRRKG
>NZ_CP047147.1|WP_003950904.1|5238848_5239787_-|cellulose-binding-protein
MSDTSPYGFELVRRGYDRAQVDERISKLVSDRDSALTRITALEKRIEELHLETQNAQAQVADAEPSYAGLGARVEKILRLAEEEAKDLREEARRAAEQHRELAESAAQQVRNDAEAFATERKAKADDEGVRIVEKAKGEASALRAEAQKDAQSKREEADALFEETRAKAAQAAADFETNLAKRREQSERDLASRQAKAEKRLAEIEHRAEQLRLEAEKLRTDAERRARQTVETAQRQAEDIVADANAKADRIRSESERELAALTNRRDSINAQLTNVREMLATLTGAAVAAAGAPAAEDDSASRGVPAQQSR
>NZ_CP047147.1|WP_159313131.1|5240047_5243911_-|hypothetical-protein
MRGYEGQERHRADDHLSRFEAEMDRLKTDREKAVQHAEDLGYQVEVLRAKLHEARRALATRPHSYDTADLGYQAEQMLRNAQLQADQMRSDAERELREVRAQTQRILQEHAEQQARLQAELHTEAVNRRQQLDQELAERRATVESHVNENVAWAEQLRARSESQAQRLLDESRAQAEQSLASARAEAQRLTEEARRRLGEETENARTEAEALLRRARADAERMLNAASQQAQEATDHAEQLRTSTASEADQAHRRSAELTRAAEQRMSEADTALREATSRSEKLVAEAEATAAKRMAAAEAAGEQRTKTAREQVARLVEEATKEAEAVRAEAEELRERAVAEAEKARSEAAEKARAAAAEDSAAALAKAARTAEEVLQKASKDAEETRRSASEEAERLRSEAEAEADRLRAEAHDLAEELKGAAKDDTKEYRAKTVELQEEARRLRGEAEQLRAEAVAEGERIRSEARREAVQQIEESATTAEELLTKAREDAAEAREAGEADGERTRAESAERAAALRKQADDALERARTEAAKLGEEAEEAAARTREEAEQAARELREETEEGVRARREEAETELVRLREEAEQRVVAAEEALTEARAEAGRLRKEAAEEAERTRTEAAERARTLSDQAVEEAEALTATAAEEAAASRAEGEAVAVRLRADAAEEAERLKAEAQEAADRLRAEAASAAERTEAEATEALERAQEEADRRRRSAEEALESARTEAGQERERAREQSEELLASARKRVEEAEAEAARLVEEADARATELVSAAEATAQQVRDSVAGLQEQAQEEIAGLRSAAEHAAERTRGEAQEEADRVRSDAHAERERASEDAARLRSEAAEELETARALAETAVSEATAESERLRADAGSYAQRLRSEASDALASAEADASKARAEARQDANRMRTEAAEQADRLVSQAATEAESLGARSTEEAERLRAEARAEAERTVTEAAEEAERLRAEAARAVAEAEERAARAREEAERVESQALAAAEELTSQARAEADRTLDEARADANKRRSEAAEQVDRLLSETAAEAEKLTTEAQQAALKATTEAESRADSMVGAARAEAERLVAEATVEGNSLVERARTDADELLVGARRDATAIRERAEELRERVTAEIEELHDRARRESSEAMRNAGERCDALVKAAEEQEAKARADAKELLADASSEAGKVRIAAVRKAEGLLKEAEQKKAELVREAEQIKREAEEEAERVVAEGQRELEVLMRRRADINQEISRVQDVLEALEGFESQPAGKAAPGGSGTGVKAGASAGSSRSGGKQNDN
>NZ_CP047147.1|WP_003950906.1|5244120_5244561_-|methylmalonyl-CoA-epimerase
MLTRIDHIGIACHDLDATVEFYRSTYGFEVFHTEVNEEQGVREAMLKINETSDGGASYLQLLEPTREDSAVGKWLAKNGEGVHHIAFGTADVDQDAADIRDKGVRVLYDEPRKGSMGSRITFLHPKDCHGVLTELVTSAPEESAEH
>NZ_CP047147.1|WP_026282219.1|5244704_5245907_+|acetyl-CoA-C-acetyltransferase
MTGTQSTTSVIVAGARTPMGRLLGSLKSFSGADLGSFAIKAALDRAGIGGDQVQYVIMGQVLTAGAGQIPARQAAVKAGIPMNVPALTINKVCLSGLDAIALADQLIRAGEFDVVVAGGQESMTNAPHLLPKSREGYKYGAVEMLDAMAHDGLTDSFENIAMGESTEKHNTRLGIARPEQDEIAALSHQRAAAAQKNGVFEAEITPVEIPQRKGDPVLFAKDEGIRAETTAESLGKLRPAFAKDGTITAGSSSQISDGAAAVVVMSKAKAEELGLEWIAEIGAHGNVSGPDNSLQSQPSNAIAHALEKDGLAVGDLDVIEINEAFAAVAVQSMKDLGVTSEKVNVNGGAIALGHPIGMSGARLVLHLALELKRRGGGIGAAALCGGGGQGDALIVRVPKS
>NZ_CP047147.1|WP_003950908.1|5245995_5246985_+|methylmalonyl-Co-A-mutase-associated-GTPase-MeaB
MQDVPALVAQAREGRPRAVARLISLVEGASPQLRDVMAALAPLTGNAYVVGLTGSPGVGKSTTTSALVSAYRAAGKRVAVLAVDPSSPFSGGALLGDRIRMSDHASDPGVYIRSMATRGHLGGLAWAAPQAIRVLDAAGFDLVLVETVGVGQSEVEIAAQADTSVVLLAPGMGDGIQAAKAGILEIGDLYVVNKADRDGADATARELNHMLGLGEARSAGDWRPPIVKTVAAKGVGVDDLVDALEKHRGWMEERGVLAERRVARAAREVETIAVTALRSRIADLSGDARTGALAAQVVGGELSPYAAADVLLDAIAPRALGAPEESAGG
>NZ_CP047147.1|WP_159313132.1|5247100_5247946_-|hypothetical-protein
MTTHRPRPASRPHRSSRALATALAAGTLLATAACSGGQEAPAARESAAAPAHHLERGPSPSPSSRLTEEGARNALITEADIEEQWQKSQAPPQSWRDSLLLGEVDAAQFVTGRSDAKECQRLVDALYDDTLLGKPSGPTALAGFEQGDSRLLYQVAGYDKKTLDAAMKWLASLPETCDTFTVTGGKGGRRTVEVTETSLPDEGDARQGLKVQLKGENEGTPVTLTLDVAAVRVGTDAFTVTNGGLDGADAPTTKNAVQHGTQRLEEVQAGHTPAPTPSEIE
>NZ_CP047147.1|WP_010642200.1|5248101_5248782_-|PepSY-domain-containing-protein
MKRNAVIAALTAVAVIGGGAAAVAVSSGDDAPATASPADRVSLVSGQESTAPADRDDDQDAKDDDRDDQRDAKDDDRDDRRDDAKDDQDDQRDDKGAAADPGNVTVAQAIAAALNHTSGTVLSADLDDDGDRRWEVEVATGGSTVHEIEVDSTTGKVVRTETDRDEDDAAAELKAVQGAKVSARDAAAAVDATVTSVEFDDGHWEVEAGEADWTVPLDTPRASREG
>NZ_CP047147.1|WP_008407901.1|5248902_5249568_+|response-regulator-transcription-factor
MRLLIVEDEKRLALSLAKGLTAEGYAVDVVHDGLEGLHRASESPYDLLVLDIMLPGMNGYRVCAALRAAGNDVPILMLTAKDGEYDEAEGLDTGADDYLTKPFSYVVLVARVRALLRRRAGAGASPVHTVGGLRVDTAARRVQRDGEEVTLTAKEFAVLEQLVLRAGEVVSKADILEHVWDFAYDGDPNIVEVYISALRRKLGAQAIRTVRGMGYRLEAGR

Crispr_ID: NZ_CP047147_32

• CRISPR_ID: NZ_CP047147_32
• CRISPR_location: 5367070-5367171
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP047147_32

Consensus_repeat	Method
GGCCTCAAGCGCCGGCCGGGCTGG	CRISPRCasFinder

spacers of NZ_CP047147_32

>32.1|5367094|54|NZ_CP047147|CRISPRCasFinder
TTCTGGCCGGGCTTCGGTCTGCGGTGCCGGTGGTCGTCCGTGGCGGTCACCGAT

CRISPR arrays and Neighbor proteins around NZ_CP047147_32

CRISPR arrays

The CRISPR arrays of NZ_CP047147_32

>merge|NZ_CP047147|32|5367070-5367171|CRISPRCasFinder
GGCCTCAAGCGCCGGCCGGGCTGGTTCTGGCCGGGCTTCGGTCTGCGGTGCCGGTGGTCGTCCGTGGCGGTCACCGATGGCCTCAAACGCCGGCCGGGCTGG

>NZ_CP047147|32|25|5367070-5367171|CRISPRCasFinder
GGCCTCAAGCGCCGGCCGGGCTGG	TTCTGGCCGGGCTTCGGTCTGCGGTGCCGGTGGTCGTCCGTGGCGGTCACCGAT
GGCCTCAAACGCCGGCCGGGCTGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_003951014.1|5369423_5370932_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatB	unknown	unknown	gnl|CDD|235489
NZ_CP047147.1|WP_159313159.1|5364838_5367007_+|EAL-domain-containing-protein	unknown	unknown	gnl|CDD|238923
NZ_CP047147.1|WP_159313163.1|5375020_5378158_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|226415
NZ_CP047147.1|WP_003951017.1|5374196_5374508_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159313164.1|5378443_5379277_+|IS5-family-transposase	unknown	unknown	gnl|CDD|379129
NZ_CP047147.1|WP_037845344.1|5362424_5364611_+|NAD-dependent-DNA-ligase-LigA	unknown	unknown	gnl|CDD|236137
NZ_CP047147.1|WP_159313160.1|5367673_5369170_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatA	unknown	unknown	gnl|CDD|234572
NZ_CP047147.1|WP_008410668.1|5360610_5361309_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|181298
NZ_CP047147.1|WP_159313161.1|5371232_5373467_+|MMPL-family-transporter	unknown	unknown	gnl|CDD|225272
NZ_CP047147.1|WP_008410656.1|5355578_5356748_+|cysteine-desulfurase	unknown	unknown	gnl|CDD|224029
NZ_CP047147.1|WP_159313155.1|5356770_5357505_-|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl|CDD|376556
NZ_CP047147.1|WP_159313162.1|5373501_5374128_+|hypothetical-protein	unknown	unknown	gnl|CDD|377085
NZ_CP047147.1|WP_159313156.1|5358756_5359533_-|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|223669
NZ_CP047147.1|WP_003951003.1|5357566_5358712_+|tRNA-2-thiouridine(34)-synthase-MnmA	unknown	unknown	gnl|CDD|234664
NZ_CP047147.1|WP_003951011.1|5367371_5367668_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC	unknown	unknown	gnl|CDD|178810
NZ_CP047147.1|WP_159313165.1|5379307_5379679_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_008410671.1|5361390_5362404_+|methionine-synthase	unknown	unknown	gnl|CDD|239426
NZ_CP047147.1|WP_159313157.1|5359588_5359951_-|DUF427-domain-containing-protein	unknown	unknown	gnl|CDD|377265
NZ_CP047147.1|WP_159313158.1|5360036_5360585_+|TIGR00730-family-Rossman-fold-protein	unknown	unknown	gnl|CDD|367590
NZ_CP047147.1|WP_008410677.1|5369166_5369406_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_003951014.1|5369423_5370932_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatB	gnl|CDD|235489	PRK05477, gatB, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB.	0
NZ_CP047147.1|WP_159313159.1|5364838_5367007_+|EAL-domain-containing-protein	gnl|CDD|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	1.60924e-104
NZ_CP047147.1|WP_159313163.1|5375020_5378158_+|AAA-family-ATPase	gnl|CDD|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	7.20845e-38
NZ_CP047147.1|WP_159313164.1|5378443_5379277_+|IS5-family-transposase	gnl|CDD|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	3.43241e-20
NZ_CP047147.1|WP_037845344.1|5362424_5364611_+|NAD-dependent-DNA-ligase-LigA	gnl|CDD|236137	PRK07956, ligA, NAD-dependent DNA ligase LigA; Validated.	0
NZ_CP047147.1|WP_159313160.1|5367673_5369170_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatA	gnl|CDD|234572	PRK00012, gatA, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA.	0
NZ_CP047147.1|WP_008410668.1|5360610_5361309_+|SDR-family-oxidoreductase	gnl|CDD|181298	PRK08219, PRK08219, SDR family oxidoreductase.	2.39264e-110
NZ_CP047147.1|WP_159313161.1|5371232_5373467_+|MMPL-family-transporter	gnl|CDD|225272	COG2409, COG2409, Predicted drug exporters of the RND superfamily [General function prediction only].	1.1468e-91
NZ_CP047147.1|WP_008410656.1|5355578_5356748_+|cysteine-desulfurase	gnl|CDD|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	2.62768e-160
NZ_CP047147.1|WP_159313155.1|5356770_5357505_-|N-acetylmuramoyl-L-alanine-amidase	gnl|CDD|376556	pfam01510, Amidase_2, N-acetylmuramoyl-L-alanine amidase. This family includes zinc amidases that have N-acetylmuramoyl-L-alanine amidase activity EC:3.5.1.28. This enzyme domain cleaves the amide bond between N-acetylmuramoyl and L-amino acids in bacterial cell walls (preferentially: D-lactyl-L-Ala). The structure is known for the bacteriophage T7 structure and shows that two of the conserved histidines are zinc binding.	4.64547e-32
NZ_CP047147.1|WP_159313162.1|5373501_5374128_+|hypothetical-protein	gnl|CDD|377085	pfam03631, Virul_fac_BrkB, Virulence factor BrkB. This family acts as a virulence factor. In Bordetella pertussis, BrkB is essential for resistance to complement-dependent killing by serum. This family was originally predicted to be ribonuclease BN, but this prediction has since been shown to be incorrect.	0.00223191
NZ_CP047147.1|WP_159313156.1|5358756_5359533_-|alpha/beta-fold-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.36472e-12
NZ_CP047147.1|WP_003951003.1|5357566_5358712_+|tRNA-2-thiouridine(34)-synthase-MnmA	gnl|CDD|234664	PRK00143, mnmA, tRNA-specific 2-thiouridylase MnmA; Reviewed.	0
NZ_CP047147.1|WP_003951011.1|5367371_5367668_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC	gnl|CDD|178810	PRK00034, gatC, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC.	1.0549e-38
NZ_CP047147.1|WP_008410671.1|5361390_5362404_+|methionine-synthase	gnl|CDD|239426	cd03310, CIMS_like, CIMS - Cobalamine-independent methonine synthase, or MetE. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme catalyses the last step in the production of methionine by transferring a methyl group from 5-methyltetrahydrofolate to L-homocysteine without using an intermediate methyl carrier. The active enzyme has a dual (beta-alpha)8-barrel structure, and this model covers both the N-and C-terminal barrel, and some single-barrel sequences, mostly from Archaea. It is assumed that the homologous N-terminal barrel has evolved from the C-terminus via gene duplication and has subsequently lost binding sites, and it seems as if the two barrels forming the active enzyme may sometimes reside on different polypeptides. The C-terminal domain incorporates the Zinc ion, which binds and activates homocysteine. Side chains from both barrels contribute to the binding of the folate substrate.	3.47784e-62
NZ_CP047147.1|WP_159313157.1|5359588_5359951_-|DUF427-domain-containing-protein	gnl|CDD|377265	pfam04248, NTP_transf_9, Domain of unknown function (DUF427). This domain contains a beta-tent fold.	4.08208e-42
NZ_CP047147.1|WP_159313158.1|5360036_5360585_+|TIGR00730-family-Rossman-fold-protein	gnl|CDD|367590	pfam03641, Lysine_decarbox, Possible lysine decarboxylase. The members of this family share a highly conserved motif PGGXGTXXE that is probably functionally important. This family includes proteins annotated as lysine decarboxylases, although the evidence for this is not clear.	1.74128e-38

Protein sequences

>NZ_CP047147.1|WP_159313159.1|5364838_5367007_+|EAL-domain-containing-protein
MEPTESAAPASWPRLRRTIAARTGPRRAPYGPGRAEGVTPLLPIAVIALAAVLLVTGIGRAVATGHALFPAGAAGWALAVLTGIVVGHLVALGRDRWWGGTGSGAALTLAVLLLYGWVPAGLVSITVVVLVGVARRHRWCQGLLHGAVDILGIAAAALLLTLTGVTPSVETPWDPRSWTLATGAGVLFAAAGYLLMTRLLLWLVHTPNPGTLPTVTRTAVIRQSLVGVALLGIAPLICVVAVALPVLLPLFSIPLIALDSTLWIARARAEEQLRDPLTGLPNRQWLLERIWTALDEAEQAGTRSALLLIDLDRFRSVNDTLGHLAGDRLLLQIAERLRPALPRGAEAARLGGDEFAVLLPVADSTTAAQRVARRLVSELGSPLDLDGLTLVLEASAGVAVYPDHAQDAEGLLRRADVAMYQAKRDRTGVEVYESKRDSNTPDRLGLLGDLRRALDAGEVELHYQPKVRFDGHVAGLEALVRWVHPERGRVPPDEFIAIAESSGLMPHLTEYVLETALGQVARWRAQGLNVPVAVNVSPRDVHSPGFAGAVAARLARHGVPAGALQLEITEHVLLEDPQRAADTLAGLTGHGVKMSLDDFGTGYSSLVHLRRLPVSELKIDRSFVARLAVDTEDAEIVRCTVDLAHSLGLLVVAEGVEDDETWERLRDLGCDAVQGWLVAAAMPAGETTAWLRARGARGWRRPAEIAAEAAEAGRAVRSGPPQ
>NZ_CP047147.1|WP_037845344.1|5362424_5364611_+|NAD-dependent-DNA-ligase-LigA
MAGEQQNADVPADARERHKHLAEQVEEHRFRYYVNDQPVVSDAEFDRQLRALTELEEQYPPLRTPDSPTQKVAGQYETEFTSVQHRERMLSLDNAFDDEELAAWAERVAKEVGAPGYHFLCELKVDGLAVNLTYEHGRLTRAATRGDGRVGEDITPNVRTISDIPERLHGDDLPALVEIRGEVFFPMEEFEKLNARLVEAGEKPFANPRNAAAGSLRQKDPRVTATRPLHMVVHGIGAREGFTIDCLSHAYDLLRSWGLPTARHNKVVEGLDGVRAFITYYGDHRHSVEHEIDGVVVKLDEVPLQGRLGSTSRAPRWAIAWKYPPEEVNSRLVDIRVGVGRTGRVTPYAQVEPVTVAGSEVEFATLHNQDVVRAKGVLIGDTVVLRKAGDVIPEILGPVADLRDGTERPFTMPAECPECGTPLKPMKEGDIDLRCPNARSCPAQLRERIYYLAGRKCLDIENFGYVAATALTQPLEPSEPPLRDEGDLFDLTVDQLLPIRSYVLDPDSGLPKRDPKTGEEKIVTFFANKQGEAKKNTLAMLDHIEAAKQRPLARVLTGLSIRHVGPVAAQALAREFRSIERIEAATEEELAQTEGVGPTIAASLKSWFAEEWHREIVRKWREAGVRMEEESTGEDEGPRPLEGLTVVVTGTLEHHTRDNAKEALQNQGAKVTGSVSKKTSFVVVGDNPGSKYDKAMQAKVPVLDEAGFAVLLGQGPDAAREVALPLPE
>NZ_CP047147.1|WP_008410671.1|5361390_5362404_+|methionine-synthase
MSDTDDFPTLRATGIGSMPGGDAREAARTVTGTFAGGEGMPYLPELPARGPGADMTGRTAGLLADLHAQLEPSGWRIADRPGRDMRRAVSWLREDLDALEEYTQGYEGPLKLQVTGVWTLAAALQTRGGEAFLGDAGACRDLAASLAEGLRGHLAEVRRRVPGARLVLQLDEPSLTAVLTGTVRTASGYRTYRAVDRQVVESALREVAAVHDGPVLAHSCAPSVPFALLRRAGFAGASFDFSLLTEGDDEALGEGVEAGFRLLAGVVPGTDTALSDPAGSVMGVRTWWRRLGLNPGLLPEAVAITPSCGLAGASPGYARAALAHCVRAANSLADNPE
>NZ_CP047147.1|WP_008410668.1|5360610_5361309_+|SDR-family-oxidoreductase
MRAMATHVITGAGSGIGAAVARRLHERGDHLVLVARDAGRARELAAAHPGAETLVADLADPDRISWALSHQTLPDRIDSLLHIAGVVDLGTVGELTPKTWRHQIDVNLLAPAELTRHFLPQLRLTHGHVVFVNSGAGLNANGGWAAYAAAKHGLKALADALRQEEQEHGVRVTSVYPGRTASAMQQKIHQQEGKEYDPDRWISPESVATTLLTALDLPADAVINDVSIRPGG
>NZ_CP047147.1|WP_159313158.1|5360036_5360585_+|TIGR00730-family-Rossman-fold-protein
MNICVFLSAADLPERYTRPAREFAELLGKGGHTLVWGGSDKGLMKVVADGVEQSGGKLLGVSVEFLAGSARPVPAESGEMIITADLAERKAQLLARADAVVIMVGGTGTLDEATEILELKKHGMHTKPVVLLNTAGFYDGLREQFQRMEDEGFLPLPLTELVLFAEEPVGALAHLEESAGVQ
>NZ_CP047147.1|WP_159313157.1|5359588_5359951_-|DUF427-domain-containing-protein
MTQGHGDDTARGHRITVEQAPVHVRVVRDGQVVAESRRPLLLRETGLPVRYYLPPEDVRTDLLTPSKTHTVCPFKGTASYWSLPGEPDLVWAYPEPIEAVAEIRDHFCFYETEVVAEPAG
>NZ_CP047147.1|WP_159313156.1|5358756_5359533_-|alpha/beta-fold-hydrolase
MDTVVSRDGTPIAYGTRGSGPALVLVGGAMTTGEHAAPLAGLLADSFTVVTYDRRGRGRSGDTRPYAVGREVEDLAEVIRAVGGPAALYGVSSGAALALHAASAGTAVSRVALYEPPFTVGEADPSRREAYRSRLVALLAADDRGGAVELFMTRIGLPPEMIAGARRSPAWPGLEAVAPTLAYDDELLGDGAPPLDRLALVSVPALVMAGSASPPAMTEAARTVAEALPKGTYRELDGQTHDVAPEAVAAALREFLLP
>NZ_CP047147.1|WP_003951003.1|5357566_5358712_+|tRNA-2-thiouridine(34)-synthase-MnmA
MTETSPRTENPPRPLRVLAAMSGGVDSAVAAARAAEAGHDVTGVHLALSANPQSFRTGARGCCTIEDSRDARRAADVIGIPFYVWDLAERFREDVVEDFVAEYEAGRTPNPCLRCNEKIKFAALLDKALALGFDAVCTGHYATVVTREDGSRELHRASDMAKDQSYVLGVLDERQLAHALFPLGDTLTTKDEIRAEAERRGLAVAKKPDSHDICFIADGDTRGFLAGRLGTAEGDILDEAGQKVGTHEGAYGYTIGQRKGLRIGTPAADGKPRYVLDISPVDNTVTVGPAAALDVTGLTAIRPRWCGTPPEGSGRYTAQLRAHGEETPVTAEVREGELTVTFDEPVRGVAPGQAVVLYDGSRVVGSATIAATRRAGAVPAA
>NZ_CP047147.1|WP_159313155.1|5356770_5357505_-|N-acetylmuramoyl-L-alanine-amidase
MGNGNHSAGAGRGADGGQGARRRTVRRRSVLIGAGVAAATGGVLAREELGRLWYQVPGVSKPRVEGAVDYAKAEWVAASDANWRRADRPDDFTVDRVIIHVVQGSYAVALKVFQDPAHRAATHYVVGKDGRVAQLIRELDVAYQAGNREYNERAVGIEHEGFVDRPQDFTGAMYESSARLTADICLRHGIPVDRKHVIGHVEVPGTDHTDPGPHWDWDRYLRLVRAAKKQLEREREQDERRERA
>NZ_CP047147.1|WP_008410656.1|5355578_5356748_+|cysteine-desulfurase
MAYLDHAATTPMLPEAVEAMSAQLTRTGNASSLHAAGRRARRTAEEARETLAEALGARPSEVVITAGGTEADNLAVKGLYWARRAADPRRTRVLASPVEHHAVLDAVHWLGEHEGATVEYLPVDTLGRVHPEALREALARNPHDVALATVMWANNEIGTVQPVTELAAVAAEYEIPLHADAVQAFGQLPLEFGASGLAAATVSGHKIGGPYGIGALLLGRQYTPVPVLHGGGQERHVRSGTLDVPAIASFAVAGQLAAERRPRFAEEIGALRDELVAAVHDAVPDAILGGDPDPAGRLPANAHFTFPGCEGDSLLLLLDAQGIECSTGSACTAGVAQPSHVLLATGTPPDLARGTLRFSLGHTSTRADVEAVAKAIGPAVERARNAGLS
>NZ_CP047147.1|WP_003951011.1|5367371_5367668_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC
MPGITREEVAHLARLARLELKAEELEHFAGQLDDILGAVARVSEVAGQDVPPTSHPLPMTNVMRADEVRPSLTPEQALSGAPAQEQQRFKVPQILGED
>NZ_CP047147.1|WP_159313160.1|5367673_5369170_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatA
MSDSIIKLTAAETAAKIASGELAAVEVTEAHLARIEAVDEKVHAFLHVDREGALAQARAVDAKRAAGEKLGPLAGVPLALKDIFTTEGIPTTVGSKILEGWIPPYDATVTKRLKDADVVILGKTNMDEFAMGSSTENSAYGPTGNPWDLTRIPGGSGGGSSAALAAFEAPLAIGTDTGGSIRQPAAVTGTVGVKPTYGGVSRYGMVAFSSSLDQGGPCARTVLDAALLHEAIAGHDPLDSTSIDAPVPPVVEAARNGSVAGMRVGVVKQFRGEGYQAGVVQRFDESVELLRKLGATVVELDCPSFDLALSAYYLIAPSECSSNLARFDAMRYGLRVGDDGTRSAEEVTAITREEGFGDEVKRRVILGTYALSSGYYDAYYGSAQKVRTLITRDFERAFEEVDVIVSPTTPTTAFPIGERADDPMAMYLADLCTIPTNLAGNAAMSLPCGLAPEDGLPVGLQIIAPAMKDDRLYKVGAAVEAAFVEQWGHPLLEEAPSL
>NZ_CP047147.1|WP_008410677.1|5369166_5369406_+|hypothetical-protein
MSALSKAKGFKKSKTGTYLSIGTTAFGALSVYKQMKAARHDHDTLSLVDAVATAAGIVTGVALLVRELKRLGDDDVLLG
>NZ_CP047147.1|WP_003951014.1|5369423_5370932_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatB
MTVTDLVPYDDALAAYDPVMGLEVHVELGTKTKMFCGCSTELGADANSQTCPTCLGLPGSLPVVNAVGVESAVKIGLALHCEIAEWCRFARKNYFYPDMPKNFQTSQYDEPIAFDGYLDVQLEDGEVFRVEIERAHMEEDTGKSTHVGGATGRIHGASHSLLDYNRAGIPLIEIVTKPIEGAGERAPEVAKAYVAELRELIKALGVSEARMEMGQMRCDVNLSLRPKGRQEFGTRSETKNVNSLRSVERAARFEIQRHAAVLSSGGTIVQETRHFHEEDGSTTAGRIKDNAEDYRYFPEPDLVPVAPPREWVEELRSTLPELPRVRRNRLREEWGVSEHDMQSILNAGAIGPIVATIEAGADAAAARKWWMGELARNANETGRPLEGLPITPAQVARVAELVKGGDLNDKLARQVIEGVLAGEGDPDTVVEKRGLKVVSDEGALTTAVEEAIAGNPAIADKIRGGKVAAAGALVGAVMKATRGQADAARVKELILAQLGVEG
>NZ_CP047147.1|WP_159313161.1|5371232_5373467_+|MMPL-family-transporter
MAALARWCMHHRLLAVLLWLLVLGGAGTAAGLAGSAYTNDYAAGGTESGEATALIERGFPGLAGDSDTVVWHAPDSSVRAADVEQTMTHALDRIADLPGVASVAGPYAEAGTGPGGGISEDGRTAYATVTFAAQTSDISPAQAQAVVDAAHGADGDGLQVEVGGSAVALTEAPALHTAELIGVAVAAVVLFLAFGSLAASLLPIATALVSVGIAYAGIVLLGHVMTVADFAPMLGMLIGLGVGIDYALFIVTRHRTGLKQGLTVDAAAARAVATTGRAVVFAGATVCIALLGMLILRLEFLNGVAIAASLTVLLTVAASLTLLPALLAYIGPRALSRRERRRLAAEGPLPELPTGFAARWSRFVERHPKLLGVLATAVMAVLALPMLTLHLGTSDQGNNPASSTTRQAYDLLADEFGPGVNGPLTLVTEVGGAPDRLALDGLEQTLGQTEGVAGVTPVVFNDASDTALLTVVPTSSPQSEQTSALVDRLRADVLPRAEAGTGLDLKVGGMTAAYDDFAELIVGKLPLFIGVVIGLGFALLLLAFRSVGIPLKAALMNVMAVAGAFGVVVAIFQWGWGSELLGLGSSGPIEPFLPVIMVSVLFGLSMDYQVFLVSRMHEEWVATGDNTRAVRVGLAETGRVINSAAVIMISVFLAFVLSGDRLIAMFGIALAVAVALDAFVLRTLLVPALMHLLGRANWWLPGWLDRVLPRISIEGPPEQRAAHPAEVPVPRAPDEDPARSAALR
>NZ_CP047147.1|WP_159313162.1|5373501_5374128_+|hypothetical-protein
MDTKTADGKRPATGAEDEQQDTDGTTPGKTPGEEKDPAGKGAPAAAETDGDAVVHDADDADDLDADDEAATEDTATAAPTGIAAGAAAIVSVVLGVVSLTGGWLGTIASARASLIGQLETSQGAGVADQVQAIYGDSWEAAALVGGAFAAVGLLVGIGVVLRVAYWPARTGPVWVRSAAWAGVAVGLVGLLLALSKYTGLLLGVPSAG
>NZ_CP047147.1|WP_003951017.1|5374196_5374508_-|hypothetical-protein
MSRLPAACLHTHLFRGARVLVDGLADPSGYARAPRPLELALRFSDDAPADAEVLVSPESGETVLAVGAYTTEAGTSLSSRTWLVGGVEARDAGVELTIGVRVG
>NZ_CP047147.1|WP_159313163.1|5375020_5378158_+|AAA-family-ATPase
MLTDVEHKSVSPVFVGRATELDTLRRALTDVRTGEPRALLIGGEAGVGKTRLLEEFTAEATGDGALVTLGACVESGTEGLPFAPFAAVLRTLRRLLPEEFAAGAAGQEGELARLLPDLGEAALARSGEEGTARLFDLTARLLEHLAAARPVVLVVEDLHWADASTRRLIAYLFRTLRTGRLLVLASYRADDIHRRHPLRPLLAELDRLRTVQRLELPRFNRAEVAGQLAGILAAEPDDSTVDEVFARSEGNAFFVEELTVAARSGCHAGLTDSLRDLLLVRVEALPERSQHLVRLAAEAGPTTEYALLAAVARLPETDLLDALRAAVGAHILLPSEDGDGYRFRHALVREAVTDDLLPGERTRIGRQFAEALAADPTLVAPDAYATRLAGYWYRAHDAAKALPAVLRAAAEARHRHAYAEQFTLLERAMELWDGVPEEIRGALRSADHAEVYPHLTARRGPGTGEGPGAPLRYLHLMADAAVAGRLCGQRERAYKIAKKAVRMLGETRSTGETWDEPLFAAWFWVQRSRVAESVGRGDGWQELHTAQELVRGLPPSEMHAEVLSCVASWWMLHRPGPEAYAAAERAVQYARMVGADDDVELAARGTLAGLRIDSGDIDTGLAELREVLADALRRERPHQIGRCYVNLPSHLEGIGRSAEAAALIERGLKESDRYGLLFTATFLHANHAESLISLGRWDEALRSADAAAGLTGQAKPAGMAAHSRTVIALARGDLDTAVRQDAVARSRVGSHGAMPQHALPLATTRLSIAAAEGRVHDARAELRAAAETGFPPGTQRYAWPLLVAAATTESDARGLPGAEEGRADHIALVRRLAKNLVTFVPVCEAQAAWVRAELRRGEGQDTVEDWADVHQRFLPLERPWDLARVALRYAEALLADSGTRPGPGRTQAAELLRTARATARRLGARPLADSIDLLARRARLSLSTRPAATPRPDTPTDPAEALGLTRREREVLSLLVAGRTNRHIAEELFISPKTASVHVSHILAKLEVSSRGEAAAVAHRLRLVGSGAGGSGGEGGREKGVGVGA
>NZ_CP047147.1|WP_159313164.1|5378443_5379277_+|IS5-family-transposase
MLEPLLPVTVLGRPSSGRRKLIDGIRWRVRTGAPWRDLPLQYGPWQTVYGLLRRWQRDGTWPGLLTELQARADVAGLITWEVNVDSTVCRAHQHAAGARRDGQAQKEPPCGSRAEPDDHGLGRSRGGFTTKIHLAGEQGQRPLFLLVTAGQRGDSPQFVAVLEGIRVPRTGPGRARVRPLRVRGDTAYSSSANRADLRKRGIRCAIPEPADQVAHRKRRGKAGGRPSVSGREDYKALHAVECGIDRLKRNRAVATRFDKLAVRFEATVLIAAIGEWL
>NZ_CP047147.1|WP_159313165.1|5379307_5379679_+|hypothetical-protein
MLTATRVDSEGKTTVAAQYYGADSENGDRIDDPSEDALFMMISDLNDSDNTFVVVQPDEDDPVWFASVAVLDEGGYETVRRDTTRNEHEVTTATSINDIARDLTIWMAARDFPGRPTSQVSES

Crispr_ID: NZ_CP047147_33

• CRISPR_ID: NZ_CP047147_33
• CRISPR_location: 5746360-5746510
• CRISPR_type: Orphan
• Repeat_type: I-C,I-E,II-B
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP047147_33

Consensus_repeat	Method
CTGCTCCCCGCACGCGCGGGGGTGGACCC	CRISPRCasFinder

spacers of NZ_CP047147_33

>33.1|5746389|32|NZ_CP047147|CRISPRCasFinder
TCCTTGAGCGTCACGAAGGACGACGCGAACCC
>33.2|5746450|32|NZ_CP047147|CRISPRCasFinder
GTCTTGCCGTAGAGCATGAGATGGGTCGGCTT

CRISPR arrays and Neighbor proteins around NZ_CP047147_33

CRISPR arrays

The CRISPR arrays of NZ_CP047147_33

>merge|NZ_CP047147|33|5746360-5746510|CRISPRCasFinder
CTGCTCCCCGCACGCGCGGGGGTGGACCCTCCTTGAGCGTCACGAAGGACGACGCGAACCCCTGCTCCCCGCACGTGCGGGGGTGGACCCGTCTTGCCGTAGAGCATGAGATGGGTCGGCTTCTGCTCCCCGCACGCGGCGGGGGCGAGCC

>NZ_CP047147|33|26|5746360-5746510|CRISPRCasFinder
CTGCTCCCCGCACGCGCGGGGGTGGACCC	TCCTTGAGCGTCACGAAGGACGACGCGAACCC
CTGCTCCCCGCACGTGCGGGGGTGGACCC	GTCTTGCCGTAGAGCATGAGATGGGTCGGCTT
CTGCTCCCCGCACGCGGCGGGGGCGAGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_037845658.1|5758234_5759509_-|MFS-transporter	unknown	unknown	gnl|CDD|340863
NZ_CP047147.1|WP_030773185.1|5744339_5745026_+|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224715
NZ_CP047147.1|WP_037843955.1|5731332_5732742_+|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|270451
NZ_CP047147.1|WP_018469408.1|5743343_5744117_+|M23-family-metallopeptidase	unknown	unknown	gnl|CDD|366703
NZ_CP047147.1|WP_018469412.1|5736337_5737456_+|GTP-binding-protein	unknown	unknown	gnl|CDD|223597
NZ_CP047147.1|WP_008406653.1|5754242_5755277_-|DUF3071-domain-containing-protein	unknown	unknown	gnl|CDD|378619
NZ_CP047147.1|WP_010641674.1|5737538_5739986_-|DNA-topoisomerase-IV-subunit-A	unknown	unknown	gnl|CDD|235503
NZ_CP047147.1|WP_159313265.1|5753338_5754166_+|sulfurtransferase	unknown	unknown	gnl|CDD|225450
NZ_CP047147.1|WP_059214185.1|5755754_5756939_+|hypothetical-protein	unknown	unknown	gnl|CDD|223039
NZ_CP047147.1|WP_159313263.1|5734630_5736226_+|DUF3459-domain-containing-protein	unknown	unknown	gnl|CDD|200471
NZ_CP047147.1|WP_030770684.1|5751067_5752249_+|alkaline-phosphatase-family-protein	unknown	unknown	gnl|CDD|366747
NZ_CP047147.1|WP_003951322.1|5747087_5747369_-|HPr-family-phosphocarrier-protein	unknown	unknown	gnl|CDD|273389
NZ_CP047147.1|WP_030310488.1|5732744_5733707_+|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|224096
NZ_CP047147.1|WP_018469410.1|5740183_5741548_+|insulinase-family-protein	unknown	unknown	gnl|CDD|223685
NZ_CP047147.1|WP_003951317.1|5741540_5742932_+|insulinase-family-protein	unknown	unknown	gnl|CDD|223685
NZ_CP047147.1|WP_003951325.1|5750468_5751068_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159313264.1|5747516_5750396_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|131764
NZ_CP047147.1|WP_003951312.1|5733717_5734593_+|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl|CDD|223472
NZ_CP047147.1|WP_033240984.1|5756958_5758308_-|FAD-binding-protein	unknown	unknown	gnl|CDD|281959
NZ_CP047147.1|WP_044474668.1|5752292_5753093_-|VOC-family-protein	unknown	unknown	gnl|CDD|319911

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_030773185.1|5744339_5745026_+|GntR-family-transcriptional-regulator	gnl|CDD|224715	COG1802, GntR, Transcriptional regulators [Transcription].	4.02813e-41
NZ_CP047147.1|WP_037843955.1|5731332_5732742_+|extracellular-solute-binding-protein	gnl|CDD|270451	cd14748, PBP2_UgpB, The periplasmic-binding component of ABC transport system specific for sn-glycerol-3-phosphate; possesses type 2 periplasmic binding fold. This group includes the periplasmic component of an ABC transport system specific for sn-glycerol-3-phosphate (G3P) and closely related proteins from archaea and bacteria. Under phophate starvation conditions, Escherichia coli can utilize G3P as phosphate source when exclusively imported by an ATP-binding cassette (ABC) transporter composed of the periplasmic binding protein, UgpB, the transmembrane subunits, UgpA and UgpE, and a homodimer of the nucleotide binding subunit, UgpC. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.1794e-45
NZ_CP047147.1|WP_018469408.1|5743343_5744117_+|M23-family-metallopeptidase	gnl|CDD|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	4.89112e-36
NZ_CP047147.1|WP_018469412.1|5736337_5737456_+|GTP-binding-protein	gnl|CDD|223597	COG0523, COG0523, Putative GTPases (G3E family) [General function prediction only].	2.86982e-66
NZ_CP047147.1|WP_008406653.1|5754242_5755277_-|DUF3071-domain-containing-protein	gnl|CDD|378619	pfam11268, DUF3071, Protein of unknown function (DUF3071). Some members in this family of proteins are annotated as DNA-binding proteins however this cannot be confirmed. Currently no function is known.	3.71985e-61
NZ_CP047147.1|WP_010641674.1|5737538_5739986_-|DNA-topoisomerase-IV-subunit-A	gnl|CDD|235503	PRK05561, PRK05561, DNA topoisomerase 4 subunit A.	0
NZ_CP047147.1|WP_159313265.1|5753338_5754166_+|sulfurtransferase	gnl|CDD|225450	COG2897, SseA, Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism].	3.8218e-82
NZ_CP047147.1|WP_059214185.1|5755754_5756939_+|hypothetical-protein	gnl|CDD|223039	PHA03307, PHA03307, transcriptional regulator ICP4; Provisional.	0.000123878
NZ_CP047147.1|WP_159313263.1|5734630_5736226_+|DUF3459-domain-containing-protein	gnl|CDD|200471	cd11332, AmyAc_OligoGlu_TS, Alpha amylase catalytic domain found in oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), trehalose synthase (also called maltose alpha-D-glucosyltransferase), and related proteins. Oligo-1,6-glucosidase (EC 3.2.1.10) hydrolyzes the alpha-1,6-glucosidic linkage of isomaltooligosaccharides, pannose, and dextran. Unlike alpha-1,4-glucosidases (EC 3.2.1.20), it fails to hydrolyze the alpha-1,4-glucosidic bonds of maltosaccharides. Trehalose synthase (EC 5.4.99.16) catalyzes the isomerization of maltose to produce trehalulose. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.	0
NZ_CP047147.1|WP_030770684.1|5751067_5752249_+|alkaline-phosphatase-family-protein	gnl|CDD|366747	pfam01663, Phosphodiest, Type I phosphodiesterase / nucleotide pyrophosphatase. This family consists of phosphodiesterases, including human plasma-cell membrane glycoprotein PC-1 / alkaline phosphodiesterase i / nucleotide pyrophosphatase (nppase). These enzymes catalyze the cleavage of phosphodiester and phosphosulfate bonds in NAD, deoxynucleotides and nucleotide sugars. Also in this family is ATX an autotaxin, tumor cell motility-stimulating protein which exhibits type I phosphodiesterases activity. The alignment encompasses the active site. Also present with in this family is 60-kDa Ca2+-ATPase form F. odoratum.	9.86342e-40
NZ_CP047147.1|WP_003951322.1|5747087_5747369_-|HPr-family-phosphocarrier-protein	gnl|CDD|273389	TIGR01003, Phosphocarrier_protein_HPr, Phosphotransferase System HPr (HPr) Family. The HPr family are bacterial proteins (or domains of proteins) which function in phosphoryl transfer system (PTS) systems. They include energy-coupling components which catalyze sugar uptake via a group translocation mechanism. The functions of most of these proteins are not known, but they presumably function in PTS-related regulatory capacities. All seed members are stand-alone HPr proteins, although the model also recognizes HPr domains of PTS fusion proteins. This family includes the related NPr protein. [Signal transduction, PTS].	1.50318e-21
NZ_CP047147.1|WP_030310488.1|5732744_5733707_+|sugar-ABC-transporter-permease	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	1.24826e-74
NZ_CP047147.1|WP_018469410.1|5740183_5741548_+|insulinase-family-protein	gnl|CDD|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	1.23389e-75
NZ_CP047147.1|WP_003951317.1|5741540_5742932_+|insulinase-family-protein	gnl|CDD|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	6.13683e-60
NZ_CP047147.1|WP_037845658.1|5758234_5759509_-|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.63531e-19
NZ_CP047147.1|WP_159313264.1|5747516_5750396_+|GNAT-family-N-acetyltransferase	gnl|CDD|131764	TIGR02717, Uncharacterized_protein_MJ0590, acetyl coenzyme A synthetase (ADP forming), alpha domain. Although technically reversible, it is believed that this group of ADP-dependent acetyl-CoA synthetases (ACS) act in the direction of acetate and ATP production in the organisms in which it has been characterized. In most species this protein exists as a fused alpha-beta domain polypeptide. In Pyrococcus and related species, however the domains exist as separate polypeptides. This model represents the alpha (N-terminal) domain. In Pyrococcus and related species there appears to have been the development of a paralogous family such that four other proteins are close relatives. In reference, one of these (along with its beta-domain partner) was characterized as ACS-II showing specificity for phenylacetyl-CoA. This model has been constructed to exclude these non-ACS-I paralogs. This may result in new, authentic ACS-I sequences falling below the trusted cutoff.	4.00603e-105
NZ_CP047147.1|WP_003951312.1|5733717_5734593_+|carbohydrate-ABC-transporter-permease	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	8.87658e-65
NZ_CP047147.1|WP_033240984.1|5756958_5758308_-|FAD-binding-protein	gnl|CDD|281959	pfam04030, ALO, D-arabinono-1,4-lactone oxidase. This domain is specific to D-arabinono-1,4-lactone oxidase EC:1.1.3.-, which is involved in the final step of the D-erythroascorbic acid biosynthesis pathway.	5.80373e-116
NZ_CP047147.1|WP_044474668.1|5752292_5753093_-|VOC-family-protein	gnl|CDD|319911	cd07247, SgaA_N_like, N-terminal domain of Streptomyces griseus SgaA and similar domains. SgaA suppresses the growth disturbances caused by high osmolarity and a high concentration of A-factor, a microbial hormone, during the early growth phase in Streptomyces griseus. A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) controls morphological differentiation and secondary metabolism in Streptomyces griseus. It is a chemical signaling molecule that at a very low concentration acts as a switch for yellow pigment production, aerial mycelium formation, streptomycin production, and streptomycin resistance. The structure and amino acid sequence of SgaA are closely related to a group of antibiotics resistance proteins, including bleomycin resistance protein, mitomycin resistance protein, and fosfomycin resistance proteins. SgaA might also function as a streptomycin resistance protein.	2.16196e-30

Protein sequences

>NZ_CP047147.1|WP_030773185.1|5744339_5745026_+|GntR-family-transcriptional-regulator
MGIPAQSVCTAIREDIVSGVHERGSRLTEEQLARRYGVSRVPVREALRTLEAEGFVVTRRHAGACVAEPTEQEAADLLEIRMLLEPLGAARAARRRTEAHLKVLRGLVRLGQERARLGEGEDLRSLGAWFHETLAQASGSPGLTALLTQLRQKVTWMYAVDPPAAPAESWAEHGAIVDAVARGDAERARTLTAQHAERATAVHRLRFGSRTTGVRTSQHAVNIPGGRN
>NZ_CP047147.1|WP_018469408.1|5743343_5744117_+|M23-family-metallopeptidase
MAFTRPTGKHRRPHRRAARTGAGLAGVAALTTTGVVSTLASPAAAAEAPAHTGFTEAIVIGHSLADRIDDQAAAQRLAAEDAAAEQAAVEAARLQAAEAKRKAEKKRAEKVRAARAAERERLNRYVLPVEGSYVSTGYQTGGSLWSSGSHSGVDFHAPAGSAVRAVGAGTVVETGWGGAYGNEVVIQMHDGTYTQYGHLASATVSVGQTVTPGQQIAVSGSTGNSTGPHLHFEARSGADYGTDMDPVAYLRGHGVDV
>NZ_CP047147.1|WP_003951317.1|5741540_5742932_+|insulinase-family-protein
MSDVITPAMDLHPQPAGGAPRPWAFPAPERTTLDNGLTVLTCHRPGQQVVAVEVLLDSPLDTEPEGLDGLATIMARAFSEGTDRDSAEEFAAELERCGATLDAFADHPGVRLSLEVPVSRLEKALGLLADALRAPAFAEAEIERLVRNRLDEIPHEQANPARRAAKELSRQLFPAGSRVSRPRQGTEETVERIDAAAVRAFYERHVRPATATAVIVGDLEGTDLGALLAGSLGAWQGDAGQPNPVPPVTADDTGRVVIVDRPGAVQTQLLIGRVGPDRHDRVWPAQVLGTYSLGGTLTSRLDRVLREEKGYTYGVRSFAQVLRSTPEGTGAAMLAISGSVDTESTGPALDDLWKVLRTLAAEGLTDAELDTAVQNLVGVAPLKYETAAAVASTLADQVEQHLPDDFQARLYRMMTETGATEATAAVVSAFPADRLVTVLVGDASRIAEPVRALGIGEVSVVTG
>NZ_CP047147.1|WP_018469410.1|5740183_5741548_+|insulinase-family-protein
MGDTATARAASGGLTATEHRLANGLRVVLSEDHLTPVAAVCLWYDVGSRHEVKGRTGLAHLFEHLMFQGSAQVKGNGHFELVQGAGGSLNGTTSFERTNYFETMPAHQLELALWLEADRMGTLLTALDDESMENQRDVVKNERRQRYDNVPYGTAFEKLTALAYPEGHPYHHTPIGSMADLDAATLEDAREFFRTYYAPNNAVLSVVGDIDPGQTLAWIEKYFGSIPGHEGKRPPRDGSLPDTIGSELREVVREEVPARALMAAYRLPEDGTRAADAADVALTVLGGGESSRLYNRLVRRDRSAVAAGFGLLRLAGAPSLGWLDVKASGDVEIPAIETAVDEELARFAAEGPTAEEMERAQAQLEREWLDRLGTVAGRADELCRYAVLFGDPQLALTAVGRVLDVTADEVRQAAAERLRPDNRAVLVYEPLTAEEAGPADQTDTATGEEAAASE
>NZ_CP047147.1|WP_010641674.1|5737538_5739986_-|DNA-topoisomerase-IV-subunit-A
MARRSTKTPPPDDFEERILDIDVVDEMQGSFLEYAYSVIYSRALPDARDGMKPVHRRIVYQMNEMGLRRDRGYVKCARVVGEVMGKLHPHGDASIYDALVRMAQPFSMRLPLVDGHGNFGSLGNDDPPAAMRYTECRMADATSLMTESIDENTVDFSPNYDGQEQEPVALPAAFPNLLVNGASGIAVGMATNMPPHNLGEVVAAARHLIKHPGADLETLMRFVPGPDLPTGGRIVGLGGVRDAYATGRGTFKIRATVAVENVTARRKGLVVTELPFSVGPEKVISKIKDLVGAKKLQGIADVKDLTDREHGLRLVIEIKNGFVPEAVLEQLYKLTPMEESFGINNVALVDGQPLTLGLKELLEVYLDHRFTVVRRRSEFRRGKKRDRLHLVEGLLVALVDIDEVIRIIRDSENSAEARERLMERFSLSDIQTQYILDTPLRRLTRFDRIELESERDRLTAEIEELSRILDSDAELRKLVSSELAAVSKKYGTDRRTVLLESSGAAAAVPLQVEDTPCRVLLSSTGLLARTADATPLAEAPKRVKHDLIVSAVAATARGEVGAVTSAGRLLRLQVIDLPQLPGTDTAPSLSGGAPVAEFLTLEADERLVCLTTLDESSPGLALGTAQGVVKRVVPDYPSHKEELEVISLRDGDRIVGATELRTGEEDLVFITDEAHLLRFPASVVRPQGRPAGGMAGVKLGEGARVVSFTAVDPAVDAVVFTVAGSRGTLDDSVQTTAKVTPFDQYPRKGRATGGVRCQRFLKGEDCLSFAWAGPAPAHAAQRDGSPAPLPELDPRRDGSGLSLPKPVAAAAGPVG
>NZ_CP047147.1|WP_018469412.1|5736337_5737456_+|GTP-binding-protein
MGRQQIPVVVLAGFLGSGKTTLLNQLLWRSRGTRIGAVVNDFGAIEIDAMTVAGQVGSTVSLGNGCLCCAVDVAELDTYLERLTRPEAGLDVIVIEASGLAEPVELVRMILASENPHIRYGGLVEVVDAAEYEATRERHPELDRHLAAADLVVLNKTDRVTPAELAELLTAVRARAGDGAVTPASYGRIDPELLFDRRPQTERYGQLSFDDAREEDEPGGGREDHDDHDGHLHAAYDSASFTTGTPLHPRRLMDLLDARPEGLYRIKGFVDFGPLDPGHVYTLHAVGRFLRFAPRPWEPGEERRTQLVLIGAGIDPDALTAQLEGCRDAAREAEERHLWSVLRFVRAEEDTADPDDPEALRAAAPGTEQPVA
>NZ_CP047147.1|WP_159313263.1|5734630_5736226_+|DUF3459-domain-containing-protein
MPDSDWWRSAVIYQVYVRSFADADGDGTGDLAGVRAKLPYLAQLGVDALWFNPWYASPMADGGYDVADYRAIHPSFGTLAEAEKLIEEAAGHGIRTIVDIVPNHVSEAHPWFRAALAEGPGGPSRDLFHFRPGRGEHGELAPNDWRSEFGGPAWTRLPDGEWYLHLFAPEQPDLNWAHPAVRTEHEEILRFWFERGVAGVRIDSAALPAKDPALPDFTPGQDPHPYLDRDELHDIYRSWRAVADRYGAVFVGEVWLPDSERFARYLRPDELHTAFNFAFLSCPWEPERLRAAIRDTLAEHAPVGAPATWVLCNHDITRTVTRYGRAETGFDFAAKRFGTPTDPALGTRRARAAALLSLALPGATYLYQGEELGLPEAEIPREHIEDPMHARSGGVDPGRDGCRVPLPWTADAPHAGFSTGEPWLPQPPGWAAHAADLQDGDPASMLTLYRTALALRRATPGLGDGPLEWLESPEEVLAFRRPGGVLCLVNLGAGPVPVPEGTELLLASGALGADGVLPSDTAVWLREPAAA
>NZ_CP047147.1|WP_003951312.1|5733717_5734593_+|carbohydrate-ABC-transporter-permease
MTTRTLISPARLSRPRGRILYWTVLFLVVAVFTLVFIGPLYWMVTSGLKDTEEFARIPPTLVPDAVHPGNYGEAWQVMELSQLLFNTLYYAFGALAFQLVLDVAAAYSLSKLRPVLGKAILGAMLVTLMIPATVLVVPQYLTVLDLPVFERNLLNTPWVIWLPSVTNAFNIFLLKRFFDSIPRELLDAAAIDGASPMRTLRSVVLPISRPILGVVSIFAVVGVWKDFLWPMLALPDPGKQTLNVGIYSLASGVPENWLLAALAMASLPTLILFLIFQRNIMSGLTAGGLKG
>NZ_CP047147.1|WP_030310488.1|5732744_5733707_+|sugar-ABC-transporter-permease
MAPPTSTPTLTRRPAGTDDGAPRVKEPRQGAFARAVRRNLTAHAFLIGAVLCFGFFSWYPMVREVVLAFQKTENGVVSWAGWSNFVYVFNDPDFALAWRNTALFTLLALLLGFVVPFVIALVLNEFRHARGYLRLLVYLPVMLPPVASVLLFKYFYDPGHGLFNRLLELFGLPAQQWLQSSDTAMLSLVIASTWMNMGGACLIYLAALQTIPGELYEAAELDGAGLLRKIWHVTIPQTRLILSLLFLMQIIATMQVFTEPFLLTGGAGPEGSTTTVVHLIYQYAFNFNNYGAAAALGLVLLVVLAGFSAAYVRLNRAEQE
>NZ_CP047147.1|WP_037843955.1|5731332_5732742_+|extracellular-solute-binding-protein
MRSSGFSTPRRRRTAVTFVSALTLLSLAACGTSSSGDQDPAPGGSADAATPLDPKTKLTLTIDCMPPAAKKAELKQWKEDVATFNKTYPNITIDGRSTPGQCLEPPRFTAMLKAKSQPDVFYAYFTDLDQVLDNDGAADISAYVNEKTVPALADIDPDVMKVLKKDDKLYALPTSNYRMGLLINRGLFEKAGLDPDTPPSTWEEVREAADKIAGLGKGIAGFGEYSAGNTGGWHYTATVYGEGGEIVGPDGKAAFNDATGKRVAQNLYDMRWKDDSMGKTQLLKWGDLQKQMATDKLGMFLAAPDDITYMVQQLGADYANFGMGPMPGQKATLFGGNSYMIKKGISSDKIKAAVAWLDLKTLSPGKGQFEWSRTKADGLPVGLPQPAFFTGAAKEKDDKERADHATMPVENFRAFTDNPVDGKAEPPKAQEVYKVLDTVMSTLLTNKDADIDKLLDTAEQQVNQVLANQ
>NZ_CP047147.1|WP_003951322.1|5747087_5747369_-|HPr-family-phosphocarrier-protein
MAERRVNVGWAEGLHARPASIFVRAATASGIPVTIAKPDTAPVNAASMLAVLGLGVQGGEEIVLSADADGAEATLERLAKLVAEGLDELPETV
>NZ_CP047147.1|WP_159313264.1|5747516_5750396_+|GNAT-family-N-acetyltransferase
MDTPSDQHAYPAHWEADVVLRDGGTARIRPITADDADRLVSFYEQVSDESKYYRFFAPYPRLSAKDVRRFTHHDHVDRVGLAVTIGGEFIATVRYDRIDDRGMPASAPADEAEVAFLVQDAHQGRGVASALLEHIAAVARERGIRRFTAEVLPANTKMIKVFTDAGYQQKRSFEDGVVRLEFGLEPTDRSLAVQHAREQRAEARSVQRLLAPGSVAVVGVGRTLGGVGRSILRNIREAGFTGPVHAVNQGFPDTGDTVEGVRAHRSVRDIAEPVDLAVIAVPAERVPEAVAECGEHGVQGLVVISAGYAEQGPEGRERQRALIRQARSYGMRVIGPNAFGVINTTPETRLNASLAPELPVPGRVGLFTQSGAIGIALLSALHRDGGGADGVPNPTGVSTFVSAGNRADVSGNDVMQYWYDDPHTDVALMYLETIGNPRKFTRLARRTAAAKPLVVVQGARHSGITPTGHPAPVTRLPYATVSALLRQAGVIRVDTVTELVDVGLLLAGQPLPAGPRVAILGNSESLGLLSYDACLSQGLRPLPPRDLTTDATPEDFRAALAAALADDGCDAVVVTAIPWVGADGVPERPDGEALGAALRTAHATAPDKPVVVVHVELGGLAEALSAAAGTGPGSLATQRGPAPSPAAPDSAAPAPDEAPPVPRTRRIPAYPAAERAVRALGEAVRYAQWRREAQRPGGVPEYESIDERGAAADITRLLAAAAPGEEGAAPRAHTLGAEDTRALLARYGIEVRPTLPAPDPDTAVRAAAELGYPVALKTTAPHLRHRADLGGVRLDLADEAQLRQAYAELTGLFGTPAELRPVVQPMAPRGVDTVVRTVIDPAVGAVLTFGLAGAPSELLGDTAHRLVPVTDRDATAMVRSIRTAPLLFGWRGSAPVDTPALEELLQRVSRLVDDHPEVVDVQLEPVVVAPRGVSVLGASVRLAPPPARDDLGPRTLPAY
>NZ_CP047147.1|WP_003951325.1|5750468_5751068_+|hypothetical-protein
MAKTGTTTQGLRAAIERSGYYPALVAEAVEAAVGGEPVASYLVHQETTFDANEVRRHVTVLVLTPTRFIVSHTDEQAADSGSPTALATTSTESVKTGRISSVVLSRVVANPESYTPGTLPREVVLTIGWGAVSRIDLEPAACGDPNCEADHGYTGSSTADDLSLRVSEAGDGPDTVRQALAFAQALSEATAATATPAGR
>NZ_CP047147.1|WP_030770684.1|5751067_5752249_+|alkaline-phosphatase-family-protein
MPSSAWPEPLPLASAPVPAYGSGSLADLLPTLAAGSGVPGMTATLTELPPADRNCVFLIDGLGWHQLLAHPAEAPFLSSLIPTSRGGTGQPLTAGFPATTATSLASVGTGRTPGEHGLPGYTALNPDSGELMNQLRWKPWTDPHAWQPHPTVFSLADAAGVHTAQVSAPGFHHTPLTQVALSGGTFHGRLSGEERMDLAAAQLAAGDRALVYTYYSEVDGKGHRFGVDSDAWRGQLMYVDGLARRLAEQLPPRSALYITADHGMVDIPFDDRHRFDVDEDWELNAGIRLLGGEGRARHLYAVPGAARDVRTVWREVLGEQCWVAGRDEAIEAGWFGPHVEKRVRDRLGDVIVAARDDVAITATRREPNESALTGMHGSMTPAEQLVPLLEVRT
>NZ_CP047147.1|WP_044474668.1|5752292_5753093_-|VOC-family-protein
MSVVRGQTVDQRTERPVPGTPCWVSLMADDLVASQEFYGRLFGWEFRPGPEQLGPYARALLDGRVVAGIGRMPEGQSLPVAWTPYLAADDVDETAGTVRHCGGTVGVGPLDAEEAGRMALAADPSGAAFGIWQGREHRGAAVEGVPGSVLWNELVTRETAGVLPFYRAAFGFEAEREEAAEDAATLLLDGRPVASVLGVGQALGELGAAHWHTHFAVEDPDETVNRVIELGGRVQRPPRDGSHGRTATVADPWGAVFTVARPDTRA
>NZ_CP047147.1|WP_159313265.1|5753338_5754166_+|sulfurtransferase
MNAIISATALAGELQGPRPPVLLDVRWQLGGPDQRPAYLAGHLPGAVHVDLDGELAGGPGKGGRHPLPDVEAFGVAMRAAGVDAGRPVVTYDGGQGWAAARAWWLLRWAGHPEVRVLDGGLAAWDGPLEEGEVTPEPGDFTPEPGRLELLDADGAAALAASGVLLDARAAERYRGDVEPIDRVGGHIPGAVSAPTTENTGEDGRLLPAAELADRFAALGANPGRKVGVYCGSGVSGAHEVLALAVAGVDAALYVGSWSDWSADPDRPVATGPQPG
>NZ_CP047147.1|WP_008406653.1|5754242_5755277_-|DUF3071-domain-containing-protein
MPELRVVAVSNDGTRLVLKAADSTEYTLPIDERLRAAVRGDRPRLGQIEIEVESHLRPRDIQARIRAGASAEEVASLAGIPVDRVRRFEGPVLAERAFMAERARKTPVRRPGENTGPQLGEAVRERLLLRGADRDTVQWDSWRRDDGTWEVLLVYGVAGERHSASWSYDPPRRLVQAVDDEARSLIGESDDVSAPEPSFPFVPRIARLPRERPERPERGPHAVEPETEELPATAEQGGRDSLTSLLEAVPSFRGDMVVPERPAAERPLEEPEQEQEAEEPPAPAASAGSAYADVLMPRAVAAHRDRLIGSTDRQAEADGVRPGRRAAVPSWDEIVFGTRRKNKE
>NZ_CP047147.1|WP_059214185.1|5755754_5756939_+|hypothetical-protein
MRETTQVKEVGTRSGEEPQEEAKRIDLSVPQVAGSAVAAVAGAVAASQLGVYGTVIGAGVMSVVATTGGSVFQHLFRRTGEQIRDVAHVRPKGEPGPDVPDTFRADPEPDPLTDPAPGRVASADPATAHTVPGDPPAPVEATQLLGRIDPAAPRPADAEATQLLGQADPEATQLLSQADPGATQLLGQAGPDATRALRVPAADPAEADQATRLLRAVPEPSGPETGEFGEATTHQARTGRWKRPLISAAAVFVLAMGGITGWELVSGHALSGDSGPTISHLTGNRSQPSGDQEEEKAPAPEETPSGEAPSDGGSGTPSTQDPEDGTSSTGTPEEGTSPAPTRPGQQPGTPDDSTGDRSPTPTPTPSAGEPEQPTGQPSGGVPSGAAPEEDAPAG
>NZ_CP047147.1|WP_033240984.1|5756958_5758308_-|FAD-binding-protein
MDEQQTQGSTRTASPVRTRNGTWRNWAGTVAARPARETVPASAAELAGAVRDAAAHGMRVKAVGTGHSFTAAAATDGLLIRPDLLTGIQIDHEAGTVTVAAGTPLKRLNVALAREGLSLTNMGDIMEQTVAGATSTGTHGTGRASASLSAQITALELVTADGSLLSCSREQNPELFAAARIGLGALGVITSLTFAVEPVFLLRAREEPMGFDQVTAEFDQLVAENEHFEFYWFPHTGNCSTKRNNRTPGPAAPVGRLSGWFEDEFLSNGVFQAANTLGRAVPATIPSLARLSSRALSARTYTDIPYKVFTSPRRVRFVEMEYAVPREALVPALRELRAMVDRSPLRVSFPVEVRTAPADDIALSTASGRETAYIAVHLYKGTPYQAYFTAAERIFTAHEGRPHWGKIHTRDAEYFAEVYPRFAEFTALRDRLDPDRLFGNDYLRRVLGD
>NZ_CP047147.1|WP_037845658.1|5758234_5759509_-|MFS-transporter
MPSPYRAIFSAPGSRGFSAAGFVGRLPLSMMGIGIVTMISQLTGRYGLAGALSAMVALSAALIGPQISRLVDLHGQRRVLRPATLVALAAVAGLLLSAQFSLPDWTLFLFAAGIGAVPSIGSMVRARWAALYRDQPRQLHTAYSFESVVDEACFIFGPIVSIGLSTTWFPEAGPLLAAVFLAAGVFSLTAQRSTEPVPHPREHHTKGSALRSTGLQVLVGTFVATGAIFGAIDVVTVAFAEEQGHKGAASLVLATYAAGSCLAGVVFGLLHFGGAPARRWLLGVVAMGVSMIPLQLVGNLPFLAVALFVAGLCIAPTMITTMALVEQHVPRAKLTEGMTWVSTGLAVGVALGSSVSGWVIDAAGAKAGYWVPAAAGAAAVLVGFLGYRRLSSPAPQREGPDGRAADAGQHQDGESGTHQERDLA

Crispr_ID: NZ_CP047147_34

• CRISPR_ID: NZ_CP047147_34
• CRISPR_location: 5756171-5756316
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP047147_34

Consensus_repeat	Method
CGAGGCCACCCAGCTCCTGGGCC	CRISPRCasFinder

spacers of NZ_CP047147_34

>34.1|5756194|34|NZ_CP047147|CRISPRCasFinder
GGATCGATCCCGCCGCCCCGCGCCCCGCCGACGC
>34.2|5756251|43|NZ_CP047147|CRISPRCasFinder
AGGCCGACCCGGAGGCGACCCAGCTCCTGAGTCAGGCAGACCC

CRISPR arrays and Neighbor proteins around NZ_CP047147_34

CRISPR arrays

The CRISPR arrays of NZ_CP047147_34

>merge|NZ_CP047147|34|5756171-5756316|CRISPRCasFinder
CGAGGCCACCCAGCTCCTGGGCCGGATCGATCCCGCCGCCCCGCGCCCCGCCGACGCCGAGGCCACCCAGCTCCTGGGCCAGGCCGACCCGGAGGCGACCCAGCTCCTGAGTCAGGCAGACCCCGGGGCGACCCAGCTCCTCGGCC

>NZ_CP047147|34|27|5756171-5756316|CRISPRCasFinder
CGAGGCCACCCAGCTCCTGGGCC	GGATCGATCCCGCCGCCCCGCGCCCCGCCGACGC
CGAGGCCACCCAGCTCCTGGGCC	AGGCCGACCCGGAGGCGACCCAGCTCCTGAGTCAGGCAGACCC
CGGGGCGACCCAGCTCCTCGGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_037845658.1|5758234_5759509_-|MFS-transporter	unknown	unknown	gnl|CDD|340863
NZ_CP047147.1|WP_030773185.1|5744339_5745026_+|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224715
NZ_CP047147.1|WP_033240984.1|5756958_5758308_-|FAD-binding-protein	unknown	unknown	gnl|CDD|281959
NZ_CP047147.1|WP_033240982.1|5759628_5760744_+|ferrochelatase	unknown	unknown	gnl|CDD|234585
NZ_CP047147.1|WP_008406633.1|5766023_5766482_-|DUF3093-domain-containing-protein	unknown	unknown	gnl|CDD|378627
NZ_CP047147.1|WP_026048246.1|5764818_5765754_+|hypothetical-protein	unknown	unknown	gnl|CDD|378945
NZ_CP047147.1|WP_159313265.1|5753338_5754166_+|sulfurtransferase	unknown	unknown	gnl|CDD|225450
NZ_CP047147.1|WP_003951336.1|5762843_5764115_+|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NZ_CP047147.1|WP_003951340.1|5766539_5767124_+|PaaI-family-thioesterase	unknown	unknown	gnl|CDD|239527
NZ_CP047147.1|WP_033240980.1|5762184_5762838_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NZ_CP047147.1|WP_030770684.1|5751067_5752249_+|alkaline-phosphatase-family-protein	unknown	unknown	gnl|CDD|366747
NZ_CP047147.1|WP_003951322.1|5747087_5747369_-|HPr-family-phosphocarrier-protein	unknown	unknown	gnl|CDD|273389
NZ_CP047147.1|WP_003951337.1|5764509_5764806_+|DUF4193-domain-containing-protein	unknown	unknown	gnl|CDD|379391
NZ_CP047147.1|WP_008406653.1|5754242_5755277_-|DUF3071-domain-containing-protein	unknown	unknown	gnl|CDD|378619
NZ_CP047147.1|WP_003951317.1|5741540_5742932_+|insulinase-family-protein	unknown	unknown	gnl|CDD|223685
NZ_CP047147.1|WP_018469396.1|5760777_5761587_+|inositol-monophosphatase	unknown	unknown	gnl|CDD|238817
NZ_CP047147.1|WP_003951325.1|5750468_5751068_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159313264.1|5747516_5750396_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|131764
NZ_CP047147.1|WP_018469408.1|5743343_5744117_+|M23-family-metallopeptidase	unknown	unknown	gnl|CDD|366703
NZ_CP047147.1|WP_044474668.1|5752292_5753093_-|VOC-family-protein	unknown	unknown	gnl|CDD|319911

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_030773185.1|5744339_5745026_+|GntR-family-transcriptional-regulator	gnl|CDD|224715	COG1802, GntR, Transcriptional regulators [Transcription].	4.02813e-41
NZ_CP047147.1|WP_033240984.1|5756958_5758308_-|FAD-binding-protein	gnl|CDD|281959	pfam04030, ALO, D-arabinono-1,4-lactone oxidase. This domain is specific to D-arabinono-1,4-lactone oxidase EC:1.1.3.-, which is involved in the final step of the D-erythroascorbic acid biosynthesis pathway.	5.80373e-116
NZ_CP047147.1|WP_033240982.1|5759628_5760744_+|ferrochelatase	gnl|CDD|234585	PRK00035, hemH, ferrochelatase; Reviewed.	1.32056e-128
NZ_CP047147.1|WP_008406633.1|5766023_5766482_-|DUF3093-domain-containing-protein	gnl|CDD|378627	pfam11292, DUF3093, Protein of unknown function (DUF3093). This family of proteins with unknown function appears to be restricted to Actinobacteria. Some members are annotated as alanine rich membrane proteins however this cannot be confirmed.	1.57638e-49
NZ_CP047147.1|WP_026048246.1|5764818_5765754_+|hypothetical-protein	gnl|CDD|378945	pfam12787, EcsC, EcsC protein family. Proteins in this family are related to EcsC from B. subtilis. This protein is found in an operon with EcsA and EcsB which are components of an ABC transport system. The function of this protein is unknown.	0.000125237
NZ_CP047147.1|WP_159313265.1|5753338_5754166_+|sulfurtransferase	gnl|CDD|225450	COG2897, SseA, Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism].	3.8218e-82
NZ_CP047147.1|WP_003951336.1|5762843_5764115_+|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.86374e-51
NZ_CP047147.1|WP_003951340.1|5766539_5767124_+|PaaI-family-thioesterase	gnl|CDD|239527	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not been determined. Sequence similarity between PaaI, E. coli medium chain acyl-CoA thioesterase II, and human thioesterase III suggests they all belong to the same thioesterase superfamily. The conserved fold present in these thioesterases is referred to as an asymmetric hot dog fold, similar to those of 4-hydroxybenzoyl-CoA thioesterase (4HBT) and the beta-hydroxydecanoyl-ACP dehydratases (FabA/FabZ).	1.00993e-11
NZ_CP047147.1|WP_033240980.1|5762184_5762838_+|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	7.34314e-69
NZ_CP047147.1|WP_030770684.1|5751067_5752249_+|alkaline-phosphatase-family-protein	gnl|CDD|366747	pfam01663, Phosphodiest, Type I phosphodiesterase / nucleotide pyrophosphatase. This family consists of phosphodiesterases, including human plasma-cell membrane glycoprotein PC-1 / alkaline phosphodiesterase i / nucleotide pyrophosphatase (nppase). These enzymes catalyze the cleavage of phosphodiester and phosphosulfate bonds in NAD, deoxynucleotides and nucleotide sugars. Also in this family is ATX an autotaxin, tumor cell motility-stimulating protein which exhibits type I phosphodiesterases activity. The alignment encompasses the active site. Also present with in this family is 60-kDa Ca2+-ATPase form F. odoratum.	9.86342e-40
NZ_CP047147.1|WP_037845658.1|5758234_5759509_-|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.63531e-19
NZ_CP047147.1|WP_003951337.1|5764509_5764806_+|DUF4193-domain-containing-protein	gnl|CDD|379391	pfam13834, DUF4193, Domain of unknown function (DUF4193). This domain of unknown function contains four conserved cysteines and a conserved histidine, including a CXXXXH motif.	1.90861e-60
NZ_CP047147.1|WP_008406653.1|5754242_5755277_-|DUF3071-domain-containing-protein	gnl|CDD|378619	pfam11268, DUF3071, Protein of unknown function (DUF3071). Some members in this family of proteins are annotated as DNA-binding proteins however this cannot be confirmed. Currently no function is known.	3.71985e-61
NZ_CP047147.1|WP_003951317.1|5741540_5742932_+|insulinase-family-protein	gnl|CDD|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	6.13683e-60
NZ_CP047147.1|WP_018469396.1|5760777_5761587_+|inositol-monophosphatase	gnl|CDD|238817	cd01639, IMPase, IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be recycled into inositol lipids; in eukaryotes IMPase plays a vital role in intracellular signaling. IMPase is one of the proposed targets of Li+ therapy in manic-depressive illness. This family contains some bacterial members of the inositol monophosphatase family classified as SuhB-like. E. coli SuhB has been suggested to participate in posstranscriptional control of gene expression, and its inositol monophosphatase activity doesn't appear to be sufficient for its cellular function. It has been proposed, that SuhB plays a role in the biosynthesis of phosphatidylinositol in mycobacteria.	1.292e-97
NZ_CP047147.1|WP_003951322.1|5747087_5747369_-|HPr-family-phosphocarrier-protein	gnl|CDD|273389	TIGR01003, Phosphocarrier_protein_HPr, Phosphotransferase System HPr (HPr) Family. The HPr family are bacterial proteins (or domains of proteins) which function in phosphoryl transfer system (PTS) systems. They include energy-coupling components which catalyze sugar uptake via a group translocation mechanism. The functions of most of these proteins are not known, but they presumably function in PTS-related regulatory capacities. All seed members are stand-alone HPr proteins, although the model also recognizes HPr domains of PTS fusion proteins. This family includes the related NPr protein. [Signal transduction, PTS].	1.50318e-21
NZ_CP047147.1|WP_159313264.1|5747516_5750396_+|GNAT-family-N-acetyltransferase	gnl|CDD|131764	TIGR02717, Uncharacterized_protein_MJ0590, acetyl coenzyme A synthetase (ADP forming), alpha domain. Although technically reversible, it is believed that this group of ADP-dependent acetyl-CoA synthetases (ACS) act in the direction of acetate and ATP production in the organisms in which it has been characterized. In most species this protein exists as a fused alpha-beta domain polypeptide. In Pyrococcus and related species, however the domains exist as separate polypeptides. This model represents the alpha (N-terminal) domain. In Pyrococcus and related species there appears to have been the development of a paralogous family such that four other proteins are close relatives. In reference, one of these (along with its beta-domain partner) was characterized as ACS-II showing specificity for phenylacetyl-CoA. This model has been constructed to exclude these non-ACS-I paralogs. This may result in new, authentic ACS-I sequences falling below the trusted cutoff.	4.00603e-105
NZ_CP047147.1|WP_018469408.1|5743343_5744117_+|M23-family-metallopeptidase	gnl|CDD|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	4.89112e-36
NZ_CP047147.1|WP_044474668.1|5752292_5753093_-|VOC-family-protein	gnl|CDD|319911	cd07247, SgaA_N_like, N-terminal domain of Streptomyces griseus SgaA and similar domains. SgaA suppresses the growth disturbances caused by high osmolarity and a high concentration of A-factor, a microbial hormone, during the early growth phase in Streptomyces griseus. A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) controls morphological differentiation and secondary metabolism in Streptomyces griseus. It is a chemical signaling molecule that at a very low concentration acts as a switch for yellow pigment production, aerial mycelium formation, streptomycin production, and streptomycin resistance. The structure and amino acid sequence of SgaA are closely related to a group of antibiotics resistance proteins, including bleomycin resistance protein, mitomycin resistance protein, and fosfomycin resistance proteins. SgaA might also function as a streptomycin resistance protein.	2.16196e-30

Protein sequences

>NZ_CP047147.1|WP_008406653.1|5754242_5755277_-|DUF3071-domain-containing-protein
MPELRVVAVSNDGTRLVLKAADSTEYTLPIDERLRAAVRGDRPRLGQIEIEVESHLRPRDIQARIRAGASAEEVASLAGIPVDRVRRFEGPVLAERAFMAERARKTPVRRPGENTGPQLGEAVRERLLLRGADRDTVQWDSWRRDDGTWEVLLVYGVAGERHSASWSYDPPRRLVQAVDDEARSLIGESDDVSAPEPSFPFVPRIARLPRERPERPERGPHAVEPETEELPATAEQGGRDSLTSLLEAVPSFRGDMVVPERPAAERPLEEPEQEQEAEEPPAPAASAGSAYADVLMPRAVAAHRDRLIGSTDRQAEADGVRPGRRAAVPSWDEIVFGTRRKNKE
>NZ_CP047147.1|WP_159313265.1|5753338_5754166_+|sulfurtransferase
MNAIISATALAGELQGPRPPVLLDVRWQLGGPDQRPAYLAGHLPGAVHVDLDGELAGGPGKGGRHPLPDVEAFGVAMRAAGVDAGRPVVTYDGGQGWAAARAWWLLRWAGHPEVRVLDGGLAAWDGPLEEGEVTPEPGDFTPEPGRLELLDADGAAALAASGVLLDARAAERYRGDVEPIDRVGGHIPGAVSAPTTENTGEDGRLLPAAELADRFAALGANPGRKVGVYCGSGVSGAHEVLALAVAGVDAALYVGSWSDWSADPDRPVATGPQPG
>NZ_CP047147.1|WP_044474668.1|5752292_5753093_-|VOC-family-protein
MSVVRGQTVDQRTERPVPGTPCWVSLMADDLVASQEFYGRLFGWEFRPGPEQLGPYARALLDGRVVAGIGRMPEGQSLPVAWTPYLAADDVDETAGTVRHCGGTVGVGPLDAEEAGRMALAADPSGAAFGIWQGREHRGAAVEGVPGSVLWNELVTRETAGVLPFYRAAFGFEAEREEAAEDAATLLLDGRPVASVLGVGQALGELGAAHWHTHFAVEDPDETVNRVIELGGRVQRPPRDGSHGRTATVADPWGAVFTVARPDTRA
>NZ_CP047147.1|WP_030770684.1|5751067_5752249_+|alkaline-phosphatase-family-protein
MPSSAWPEPLPLASAPVPAYGSGSLADLLPTLAAGSGVPGMTATLTELPPADRNCVFLIDGLGWHQLLAHPAEAPFLSSLIPTSRGGTGQPLTAGFPATTATSLASVGTGRTPGEHGLPGYTALNPDSGELMNQLRWKPWTDPHAWQPHPTVFSLADAAGVHTAQVSAPGFHHTPLTQVALSGGTFHGRLSGEERMDLAAAQLAAGDRALVYTYYSEVDGKGHRFGVDSDAWRGQLMYVDGLARRLAEQLPPRSALYITADHGMVDIPFDDRHRFDVDEDWELNAGIRLLGGEGRARHLYAVPGAARDVRTVWREVLGEQCWVAGRDEAIEAGWFGPHVEKRVRDRLGDVIVAARDDVAITATRREPNESALTGMHGSMTPAEQLVPLLEVRT
>NZ_CP047147.1|WP_003951325.1|5750468_5751068_+|hypothetical-protein
MAKTGTTTQGLRAAIERSGYYPALVAEAVEAAVGGEPVASYLVHQETTFDANEVRRHVTVLVLTPTRFIVSHTDEQAADSGSPTALATTSTESVKTGRISSVVLSRVVANPESYTPGTLPREVVLTIGWGAVSRIDLEPAACGDPNCEADHGYTGSSTADDLSLRVSEAGDGPDTVRQALAFAQALSEATAATATPAGR
>NZ_CP047147.1|WP_159313264.1|5747516_5750396_+|GNAT-family-N-acetyltransferase
MDTPSDQHAYPAHWEADVVLRDGGTARIRPITADDADRLVSFYEQVSDESKYYRFFAPYPRLSAKDVRRFTHHDHVDRVGLAVTIGGEFIATVRYDRIDDRGMPASAPADEAEVAFLVQDAHQGRGVASALLEHIAAVARERGIRRFTAEVLPANTKMIKVFTDAGYQQKRSFEDGVVRLEFGLEPTDRSLAVQHAREQRAEARSVQRLLAPGSVAVVGVGRTLGGVGRSILRNIREAGFTGPVHAVNQGFPDTGDTVEGVRAHRSVRDIAEPVDLAVIAVPAERVPEAVAECGEHGVQGLVVISAGYAEQGPEGRERQRALIRQARSYGMRVIGPNAFGVINTTPETRLNASLAPELPVPGRVGLFTQSGAIGIALLSALHRDGGGADGVPNPTGVSTFVSAGNRADVSGNDVMQYWYDDPHTDVALMYLETIGNPRKFTRLARRTAAAKPLVVVQGARHSGITPTGHPAPVTRLPYATVSALLRQAGVIRVDTVTELVDVGLLLAGQPLPAGPRVAILGNSESLGLLSYDACLSQGLRPLPPRDLTTDATPEDFRAALAAALADDGCDAVVVTAIPWVGADGVPERPDGEALGAALRTAHATAPDKPVVVVHVELGGLAEALSAAAGTGPGSLATQRGPAPSPAAPDSAAPAPDEAPPVPRTRRIPAYPAAERAVRALGEAVRYAQWRREAQRPGGVPEYESIDERGAAADITRLLAAAAPGEEGAAPRAHTLGAEDTRALLARYGIEVRPTLPAPDPDTAVRAAAELGYPVALKTTAPHLRHRADLGGVRLDLADEAQLRQAYAELTGLFGTPAELRPVVQPMAPRGVDTVVRTVIDPAVGAVLTFGLAGAPSELLGDTAHRLVPVTDRDATAMVRSIRTAPLLFGWRGSAPVDTPALEELLQRVSRLVDDHPEVVDVQLEPVVVAPRGVSVLGASVRLAPPPARDDLGPRTLPAY
>NZ_CP047147.1|WP_003951322.1|5747087_5747369_-|HPr-family-phosphocarrier-protein
MAERRVNVGWAEGLHARPASIFVRAATASGIPVTIAKPDTAPVNAASMLAVLGLGVQGGEEIVLSADADGAEATLERLAKLVAEGLDELPETV
>NZ_CP047147.1|WP_030773185.1|5744339_5745026_+|GntR-family-transcriptional-regulator
MGIPAQSVCTAIREDIVSGVHERGSRLTEEQLARRYGVSRVPVREALRTLEAEGFVVTRRHAGACVAEPTEQEAADLLEIRMLLEPLGAARAARRRTEAHLKVLRGLVRLGQERARLGEGEDLRSLGAWFHETLAQASGSPGLTALLTQLRQKVTWMYAVDPPAAPAESWAEHGAIVDAVARGDAERARTLTAQHAERATAVHRLRFGSRTTGVRTSQHAVNIPGGRN
>NZ_CP047147.1|WP_018469408.1|5743343_5744117_+|M23-family-metallopeptidase
MAFTRPTGKHRRPHRRAARTGAGLAGVAALTTTGVVSTLASPAAAAEAPAHTGFTEAIVIGHSLADRIDDQAAAQRLAAEDAAAEQAAVEAARLQAAEAKRKAEKKRAEKVRAARAAERERLNRYVLPVEGSYVSTGYQTGGSLWSSGSHSGVDFHAPAGSAVRAVGAGTVVETGWGGAYGNEVVIQMHDGTYTQYGHLASATVSVGQTVTPGQQIAVSGSTGNSTGPHLHFEARSGADYGTDMDPVAYLRGHGVDV
>NZ_CP047147.1|WP_003951317.1|5741540_5742932_+|insulinase-family-protein
MSDVITPAMDLHPQPAGGAPRPWAFPAPERTTLDNGLTVLTCHRPGQQVVAVEVLLDSPLDTEPEGLDGLATIMARAFSEGTDRDSAEEFAAELERCGATLDAFADHPGVRLSLEVPVSRLEKALGLLADALRAPAFAEAEIERLVRNRLDEIPHEQANPARRAAKELSRQLFPAGSRVSRPRQGTEETVERIDAAAVRAFYERHVRPATATAVIVGDLEGTDLGALLAGSLGAWQGDAGQPNPVPPVTADDTGRVVIVDRPGAVQTQLLIGRVGPDRHDRVWPAQVLGTYSLGGTLTSRLDRVLREEKGYTYGVRSFAQVLRSTPEGTGAAMLAISGSVDTESTGPALDDLWKVLRTLAAEGLTDAELDTAVQNLVGVAPLKYETAAAVASTLADQVEQHLPDDFQARLYRMMTETGATEATAAVVSAFPADRLVTVLVGDASRIAEPVRALGIGEVSVVTG
>NZ_CP047147.1|WP_033240984.1|5756958_5758308_-|FAD-binding-protein
MDEQQTQGSTRTASPVRTRNGTWRNWAGTVAARPARETVPASAAELAGAVRDAAAHGMRVKAVGTGHSFTAAAATDGLLIRPDLLTGIQIDHEAGTVTVAAGTPLKRLNVALAREGLSLTNMGDIMEQTVAGATSTGTHGTGRASASLSAQITALELVTADGSLLSCSREQNPELFAAARIGLGALGVITSLTFAVEPVFLLRAREEPMGFDQVTAEFDQLVAENEHFEFYWFPHTGNCSTKRNNRTPGPAAPVGRLSGWFEDEFLSNGVFQAANTLGRAVPATIPSLARLSSRALSARTYTDIPYKVFTSPRRVRFVEMEYAVPREALVPALRELRAMVDRSPLRVSFPVEVRTAPADDIALSTASGRETAYIAVHLYKGTPYQAYFTAAERIFTAHEGRPHWGKIHTRDAEYFAEVYPRFAEFTALRDRLDPDRLFGNDYLRRVLGD
>NZ_CP047147.1|WP_037845658.1|5758234_5759509_-|MFS-transporter
MPSPYRAIFSAPGSRGFSAAGFVGRLPLSMMGIGIVTMISQLTGRYGLAGALSAMVALSAALIGPQISRLVDLHGQRRVLRPATLVALAAVAGLLLSAQFSLPDWTLFLFAAGIGAVPSIGSMVRARWAALYRDQPRQLHTAYSFESVVDEACFIFGPIVSIGLSTTWFPEAGPLLAAVFLAAGVFSLTAQRSTEPVPHPREHHTKGSALRSTGLQVLVGTFVATGAIFGAIDVVTVAFAEEQGHKGAASLVLATYAAGSCLAGVVFGLLHFGGAPARRWLLGVVAMGVSMIPLQLVGNLPFLAVALFVAGLCIAPTMITTMALVEQHVPRAKLTEGMTWVSTGLAVGVALGSSVSGWVIDAAGAKAGYWVPAAAGAAAVLVGFLGYRRLSSPAPQREGPDGRAADAGQHQDGESGTHQERDLA
>NZ_CP047147.1|WP_033240982.1|5759628_5760744_+|ferrochelatase
MSDVRDATPYDALLLLSFGGPEGPDDVVPFLRNVTHGRGIPEERLKEVGQHYYLFDGISPINAQNRDLLAALRADFAEHGVELPVFWGNRNWSPYLPDTLREMAKEGHRRIAVLATSAYASYSGCRQYRENLADALAALEAEGLPVPRVDKLRHYFNHPGFLEPMIDGVLASLADLPEEVRDGAEIAFTTHSIPDAAADTSGPREVHGDGGAYVAQHLDTARVIADAVRERTGVDRPWSLVYQSRSGSPHIPWLEPDICDHLEERHAAGAPAVVMAPIGFVSDHMEVRYDLDTEATAKAAELGLPVRRSATVGADPRFAAAVRDLLLERAATERGEHPARCALGALGPSHDVCPVGCCPARSPRPAAAGMD
>NZ_CP047147.1|WP_018469396.1|5760777_5761587_+|inositol-monophosphatase
MTDPNTGLLALALEAARRAGDFLRDGRPADLAVAATKTSAIDVVTEMDIASEKMITGFLADRRPEDGFLGEEGASTEGTSGVRWIIDPLDGTVNYLYGRPAWAVSIAAERDGVTVVGVVHAPMRGETCRAVLGGGAHLDDTPIQVNTAPTLDRALVGTGFGYLAGRKAHQAAVAARIIPEVRDIRRGGSAAIDLCDVATGRLDAYYERGLNPWDYAAGELIAREAGALTGGRPGAPASTELTVAAPPGLFEPLQERLEEYGAWHDGTLA
>NZ_CP047147.1|WP_033240980.1|5762184_5762838_+|response-regulator-transcription-factor
MRVLVVEDEQLLADAVATGLRREAMAVDVVYDGAAALERVGVNDYDVIVLDRDLPLVHGDDVCRKVVELQMPTRVLMLTASGDVSDRVEGLEIGADDYLPKPFAFTELIARVRALGRRTSVPLPPVLERAGIKLDPNRREVFRDGREIQLAPKEFAVLEVLLRSEGAVVSAEQLLEKAWDENTDPFTNVVRVTVMTLRRKLGEPAVIVTVPGSGYRI
>NZ_CP047147.1|WP_003951336.1|5762843_5764115_+|HAMP-domain-containing-histidine-kinase
MAASPAPRPAPPKPTSAPPRPTWDPRRPPQQAWLRPTIRIRLTLLYGGMFLIAGILLLSIIYLLAAQAVHVGNELPFQVTSGTFTIYSDACPALSGRRFTSSGAFNDAMKLCIDHQRQQALDDLLSRSLLALVGLSVIAFAFGYAMAGRVLAPLGRITRTARSVAGSDLSRRIELDGPDDELKELADTFDDMLDRLERAFTAQQRFVANASHELRTPLAINRTLLEVQLSDPGAPPELQQLGKTLLATNERSEQLVEGLLLLARSDNQIVERKPVDLGEVATRAVEQVRGEAEQREVELRADIAEAVVQGNGVLLERIALNLTQNAVRYNLPPGEGGWVEVSTELQHGQAVLVVTNTGPVVPAYEIDQLFEPFRRLRTERTGSDKGVGLGLSIVRSVTRAHGGRITAEPREGGGLVMRVTLPL
>NZ_CP047147.1|WP_003951337.1|5764509_5764806_+|DUF4193-domain-containing-protein
MATDYDTPRKTDDDLNEDSIEELKARRNDKSTSTVDVDEFEAAEGLELPGADLSNEELAVRVLPKQQDEFTCMSCFLVHHRSQLAREKNGQPICRDCD
>NZ_CP047147.1|WP_026048246.1|5764818_5765754_+|hypothetical-protein
MTGTTPPRKFPFLKRRGDGAPSPAESDGERGLGASLEAADATDGAPGPHSGGSGTGEGPAATEPATPAPGRVAAVRDGLLRQGRNAKAGLGVLADRVIEIAPRIPVRDLHTLRAQFPGLGPEQLADKLISGAAHGTSTVGASVGAAAMLPVPPAMPAELAAEITAVAAIELKLIAELHEVYGQRPEGGATRRATAYLTSWTNERGIDVVRPLTITAALSGPLKRDLRQQITKRMIRNLPNLVPFLVGAAVGAVMNRRDTRKLAERVRQDLRAAQVPWDQLTSLPPLDRPELPPATLPHALPPAPRDDNRPT
>NZ_CP047147.1|WP_008406633.1|5766023_5766482_-|DUF3093-domain-containing-protein
MHPNTPQYAERLTAPRAWWALVAIAGLTSGLIVMPLGVLAMLIGLVVGAAAGAAGLSTYGSAQIRVVGDALVAGDARIPLSALGAAEPLDAEETVAWRSHKADPRAFMLLRSYIPTAVRVEVTDPADPTPYLYLSTRDPERLAAALSPVREG
>NZ_CP047147.1|WP_003951340.1|5766539_5767124_+|PaaI-family-thioesterase
MSGRTPALTPPDSALAPVRHPDAPAPGEPIGTHYEHCFGCGGEQPHGLHLAAKAGEGVSVTAEFLVRPEHQGAPGLAHGGLLATALDDTLGALNWLLRVISVTGRLETDYLRPVPVGTVLHLSAEVTAVDGRKIYATAEGRLNAPDGPVAVRADALFVEVKVEHFTDNGRPEEIQAAMDDPDQIRRVRAFEVNP

Crispr_ID: NZ_CP047147_35

• CRISPR_ID: NZ_CP047147_35
• CRISPR_location: 5924395-5924535
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers
• Cas_protein_info: csa3

Consensus repeat of NZ_CP047147_35

Consensus_repeat	Method
CCAAGCCCGGCCGGCGCTTGAGGCC	PILER-CR

spacers of NZ_CP047147_35

>35.1|5924437|41|NZ_CP047147|PILER-CR
TCTTGTGCCCGCGCTCCGGCTCGACCGTGCCGGTCAAAGAT
>35.2|5924520|10|NZ_CP047147|PILER-CR
GCTTGAGGAG

CRISPR arrays and Neighbor proteins around NZ_CP047147_35

CRISPR arrays

The CRISPR arrays of NZ_CP047147_35

>merge|NZ_CP047147|35|5924395-5924535|PILER-CR
GGCCTCAGGCGCCGGCCGGGCTGTCTTGTGCCCGCGCTCCGGCTCGACCGTGCCGGTCAAAGATGGCCTCAAGCGCCGGCCGGGCTTGAAGTCAGGTGCCGGCCGGGCTTGAGGAGGGCCTCAAGCGTCGGCCGGGCTTGG

>NZ_CP047147|35|8|5924395-5924535|PILER-CR
GGCCTCAGGCGCCGGCCGGGCTGTCTTGTGCCCGCGCTCCGG	CTCGACCGTGCCGGTCAAAGATGGCCTCAAGCGCCGGCCGG
GCTTGAAGTCAGGTGCCGGCCGGGCTTGAGGAGGGCCTCAAG	CGTCGGCCGG
GCTTGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_159313309.1|5934430_5935846_+|MFS-transporter	unknown	unknown	gnl|CDD|340890
NZ_CP047147.1|WP_003951471.1|5926983_5927928_+|DMT-family-transporter	unknown	unknown	gnl|CDD|273359
NZ_CP047147.1|WP_159313306.1|5924862_5925603_-|MerR-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl|CDD|133400
NZ_CP047147.1|WP_127453718.1|5925672_5926893_+|erythromycin-esterase-family-protein	unknown	unknown	gnl|CDD|350610
NZ_CP047147.1|WP_159313303.1|5918222_5920541_+|5-methyltetrahydropteroyltriglutamate---homocysteine-S-methyltransferase	unknown	unknown	gnl|CDD|235367
NZ_CP047147.1|WP_159313982.1|5929500_5931102_-|alkaline-phosphatase	unknown	unknown	gnl|CDD|226070
NZ_CP047147.1|WP_093844698.1|5935855_5937886_-|CocE/NonD-family-hydrolase	unknown	unknown	gnl|CDD|225487
NZ_CP047147.1|WP_159313304.1|5923009_5923561_+|hypothetical-protein	unknown	unknown	gnl|CDD|237171
NZ_CP047147.1|WP_010641447.1|5920799_5921777_+|PRC-and-DUF2382-domain-containing-protein	unknown	unknown	gnl|CDD|378207
NZ_CP047147.1|WP_008414447.1|5921877_5922816_-|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|235737
NZ_CP047147.1|WP_159313307.1|5928036_5928486_+|hotdog-fold-thioesterase	unknown	unknown	gnl|CDD|239527
NZ_CP047147.1|WP_159313301.1|5914120_5915317_+|NAD(P)-binding-protein	unknown	unknown	gnl|CDD|223727
NZ_CP047147.1|WP_030766900.1|5908561_5908741_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159313308.1|5931472_5933593_-|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|109787
NZ_CP047147.1|WP_018894712.1|5933642_5934374_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_CP047147.1|WP_159313305.1|5923645_5924374_+|helix-turn-helix-domain-containing-protein	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|238042
NZ_CP047147.1|WP_159313302.1|5917360_5917807_+|ATP-binding-protein	unknown	unknown	gnl|CDD|340413
NZ_CP047147.1|WP_003951460.1|5911262_5913464_-|discoidin-domain-containing-protein	unknown	unknown	gnl|CDD|366285
NZ_CP047147.1|WP_159313981.1|5928687_5929422_+|ATP-dependent-Lon-protease	unknown	unknown	unknown
NZ_CP047147.1|WP_159313300.1|5908921_5911186_+|heavy-metal-translocating-P-type-ATPase	unknown	unknown	gnl|CDD|319783

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP047147.1|WP_159313305.1|5923645_5924374_+|helix-turn-helix-domain-containing-protein	csa3	COG0640_csa3_CAS-I-A	4.8e-12	41.1	0.5

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_159313309.1|5934430_5935846_+|MFS-transporter	gnl|CDD|340890	cd17332, MFS_MelB_like, Salmonella enterica Na+/melibiose symporter MelB and similar transporters of the Major Facilitator Superfamily. This family is composed of Salmonella enterica Na+/melibiose symporter MelB, Major Facilitator Superfamily domain-containing proteins, MFSD2 and MFSD12, and other sugar transporters. MelB catalyzes the electrogenic symport of galactosides with Na+, Li+ or H+. The MFSD2 subfamily is composed of two vertebrate members, MFSD2A and MFSD2B. MFSD2A is more commonly called sodium-dependent lysophosphatidylcholine symporter 1 (NLS1). It is an LPC symporter that plays an essential role for blood-brain barrier formation and function. Inactivating mutations in MFSD2A cause a lethal microcephaly syndrome. MFSD2B is a potential risk or protect factor in the prognosis of lung adenocarcinoma. MelB-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.08592e-55
NZ_CP047147.1|WP_003951471.1|5926983_5927928_+|DMT-family-transporter	gnl|CDD|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	4.2885e-15
NZ_CP047147.1|WP_159313306.1|5924862_5925603_-|MerR-family-DNA-binding-transcriptional-regulator	gnl|CDD|133400	cd04773, HTH_TioE_rpt2, Second Helix-Turn-Helix DNA binding domain of the regulatory protein TioE. Putative helix-turn-helix (HTH) regulatory protein, TioE, and related proteins. TioE is part of the thiocoraline gene cluster, which is involved in the biosynthesis of the antitumor thiocoraline from the marine actinomycete, Micromonospora. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. Proteins in this family are unique within the MerR superfamily in that they are composed of just two adjacent MerR-like N-terminal domains; this CD mainly contains the C-terminal or second repeat (rpt2) of these tandem MerR-like domain proteins.	1.87724e-35
NZ_CP047147.1|WP_127453718.1|5925672_5926893_+|erythromycin-esterase-family-protein	gnl|CDD|350610	cd14728, Ere-like, Erythromycin esterase and succinoglycan biosynthesis related proteins. This group contains erythromycin esterase, which shares conserved active site residues of the Tiki/TraB family. Erythromycin esterases (EreA and EreB) disrupt erythromycin via the hydrolysis of the macrolactone ring. A critical catalytic histidine acts as a general base in the activation of a water molecule. Macrolides act by inhibiting bacterial protein synthesis by binding at the exit tunnel of ribosomal subunit 50s, blocking the translation of the polypeptide. Erythromycin esterase, typically found in integrons and transposons, confers antibiotic resistance through the disruption of the drug ring structure. EreB substrate profile is substantially broader than that for EreA, being able to also metabolize semisynthetic derivatives such as azalide azithromycin.	3.57569e-65
NZ_CP047147.1|WP_159313303.1|5918222_5920541_+|5-methyltetrahydropteroyltriglutamate---homocysteine-S-methyltransferase	gnl|CDD|235367	PRK05222, PRK05222, 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional.	0
NZ_CP047147.1|WP_159313982.1|5929500_5931102_-|alkaline-phosphatase	gnl|CDD|226070	COG3540, PhoD, Phosphodiesterase/alkaline phosphatase D [Inorganic ion transport and metabolism].	2.538e-148
NZ_CP047147.1|WP_093844698.1|5935855_5937886_-|CocE/NonD-family-hydrolase	gnl|CDD|225487	COG2936, COG2936, Predicted acyl esterases [General function prediction only].	1.15452e-110
NZ_CP047147.1|WP_159313304.1|5923009_5923561_+|hypothetical-protein	gnl|CDD|237171	PRK12678, PRK12678, transcription termination factor Rho; Provisional.	4.39167e-05
NZ_CP047147.1|WP_010641447.1|5920799_5921777_+|PRC-and-DUF2382-domain-containing-protein	gnl|CDD|378207	pfam09557, DUF2382, Domain of unknown function (DUF2382). This entry describes an uncharacterized domain, sometimes found in association with a PRC-barrel domain pfam05239 which is also found in rRNA processing protein RimM and in a photosynthetic reaction centre complex protein). This domain is found in proteins from Bacillus subtilis, Deinococcus radiodurans, Nostoc sp. PCC 7120, Myxococcus xanthus, and several other species. The function is not known.	2.08627e-34
NZ_CP047147.1|WP_008414447.1|5921877_5922816_-|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|235737	PRK06197, PRK06197, short chain dehydrogenase; Provisional.	2.49711e-107
NZ_CP047147.1|WP_159313307.1|5928036_5928486_+|hotdog-fold-thioesterase	gnl|CDD|239527	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not been determined. Sequence similarity between PaaI, E. coli medium chain acyl-CoA thioesterase II, and human thioesterase III suggests they all belong to the same thioesterase superfamily. The conserved fold present in these thioesterases is referred to as an asymmetric hot dog fold, similar to those of 4-hydroxybenzoyl-CoA thioesterase (4HBT) and the beta-hydroxydecanoyl-ACP dehydratases (FabA/FabZ).	4.32491e-22
NZ_CP047147.1|WP_159313301.1|5914120_5915317_+|NAD(P)-binding-protein	gnl|CDD|223727	COG0654, UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion].	8.77707e-35
NZ_CP047147.1|WP_159313308.1|5931472_5933593_-|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|109787	pfam00743, FMO-like, Flavin-binding monooxygenase-like. This family includes FMO proteins, cyclohexanone mono-oxygenase and a number of different mono-oxygenases.	1.49631e-69
NZ_CP047147.1|WP_018894712.1|5933642_5934374_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	5.05073e-09
NZ_CP047147.1|WP_159313305.1|5923645_5924374_+|helix-turn-helix-domain-containing-protein	gnl|CDD|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.25974e-13
NZ_CP047147.1|WP_159313302.1|5917360_5917807_+|ATP-binding-protein	gnl|CDD|340413	cd16936, HATPase_RsbW-like, Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains. This family includes histidine kinase-like ATPase (HATPase) domain of RsbW, an anti sigma-B factor as well as a serine-protein kinase involved in regulating sigma-B during stress in Bacilli. The alternative sigma factor sigma-B is an important regulator of the general stress response of Bacillus cereus and B. subtilis. RsbW is an anti-sigma factor while RsbV is an anti-sigma factor antagonist (anti-anti-sigma factor). RsbW can also act as a kinase on RsbV. In a partner-switching mechanism, RsbW, RsbV, and sigma-B participate as follows: in non-stressed cells, sigma-B is present in an inactive form complexed with RsbW; in this form, sigma-B is unable to bind to RNA polymerase. Under stress, RsbV binds to RsbW, forming an RsbV-RsbW complex, and sigma-B is released to bind to RNA polymerase. RsbW may then act as a kinase on RsbV, phosphorylating a serine residue; RsbW is then released to bind to sigma-B, hence blocking its ability to bind RNA polymerase. A phosphatase then dephosphorylates RsbV so that it can again form a complex with RsbW, leading to the release of sigma-B.	3.60776e-15
NZ_CP047147.1|WP_003951460.1|5911262_5913464_-|discoidin-domain-containing-protein	gnl|CDD|366285	pfam00754, F5_F8_type_C, F5/8 type C domain. This domain is also known as the discoidin (DS) domain family.	4.13397e-28
NZ_CP047147.1|WP_159313300.1|5908921_5911186_+|heavy-metal-translocating-P-type-ATPase	gnl|CDD|319783	cd02094, P-type_ATPase_Cu-like, P-type heavy metal-transporting ATPase, similar to human copper-transporting ATPases, ATP7A and ATP7B. The mammalian copper-transporting P-type ATPases, ATP7A and ATP7B are key molecules required for the regulation and maintenance of copper homeostasis. Menkes and Wilson diseases are caused by mutation in ATP7A and ATP7B respectively. This subfamily includes other copper-transporting ATPases such as: Bacillus subtilis CopA , Archeaoglobus fulgidus CopA, and Saccharomyces cerevisiae Ccc2p. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0

Protein sequences

>NZ_CP047147.1|WP_159313305.1|5923645_5924374_+|helix-turn-helix-domain-containing-protein
MGTEPAAPGSAAERVAALAALLADETRAVICLALLDGRAWTAGELARRAGVAASTATEHLNRLVAGGLLAQERQGRHRYVRLADPGAARLVEGLAARAVPGGERPVGLRAVRAGSRLARGRTCYDHLAGRIGVAVTDAMVGRGLLAPDADLTPTRAGRTWFAAQGLDLTPPGRRPVTRACLDWTERRPHLAGHAGALLCRHTFDHGWCRRVGTDRAVEITPEGEEHLGALLGIEAGAWRLPD
>NZ_CP047147.1|WP_159313304.1|5923009_5923561_+|hypothetical-protein
MDERIETKAPPVYVATTSPAHIPGITAPSAGAAEKDGDATGGTPDDAAPAEDAAPEEAAPEERAAEPEPEPEAAEDAAEEATEPEGGEAPADGPVFEAADRRAAVTADADGIRLRLDDQEAEFTWEEVAAVESSVSRFGRRLLVAVHTPGPWRYPAEVEADGKEQAKEWLTALDAVLDAYFEE
>NZ_CP047147.1|WP_008414447.1|5921877_5922816_-|SDR-family-NAD(P)-dependent-oxidoreductase
MAPRTTPRPLPDLSGTTAVVTGANSGIGAATTLALAKGGARVVMACRDLAKAERTAAAVRRVVPEAKVPLVGLDLADLSSVAEAAEEIGRTSGGRVDLLVNNAGVMALPERRTADGFEMQFGTNHLGHFALTAHLLPYLGTDGPARVVTVSSLAHRMGRIDFDNLNAERGYGSWPAYGRSKLANLLFTAELARRARAAGLDLTAVSAHPGLAATELGQAGPKMAGHSWAARMERATRLFTQPASSGALPVLLAATDPAARGGAYYGPAGPLECRGGAGPARLSARAKDPVTARRLWDVSAALTGVDPGLEPA
>NZ_CP047147.1|WP_010641447.1|5920799_5921777_+|PRC-and-DUF2382-domain-containing-protein
MTAGDSFLTTDQLVGLTAYDRDGAKVGSVEQVFLDDATGKPEWVTVKTGMFGMKETFVPLAGAGHDGEGLHLAYAKDTIKDAPRVDADEHLDAAEERELYAHYGVTRGGSGKTGEEMSGRTDTSGKDTGMDTGTKAAAAGTAGAAGAAGAAGAGGRSQSGMDRPAEDRPLAGAGMSRSAAETGDDRAKYADEMVRSEEQLRVGTEEQEVGRARLRKVVVTEDVSTTVPVSHEEVHLVREPIGEGDRTRGTEIGEAEAEVTLHAERPVVRKEAVAVERVRLETEKVTEQREVSDTVRKEEIQYDDGTGSASGEEDDWKGGRSGPTR
>NZ_CP047147.1|WP_159313303.1|5918222_5920541_+|5-methyltetrahydropteroyltriglutamate---homocysteine-S-methyltransferase
MTAKSAAAAARSTVYGYPRQGQHRELKKAVEGYWKGRVGADALKETAAELRRANWAQLAEAGIDEVPTGDFSYYDHVLDTSVMVGAVPPRHRAAVDADPLDGYFAMARGNQDVAPLEMTKWFDTNYHYLVPELGPDTVFTADSAKQVAELAEALALGHTARPVLVGPVTYLLLAKPAPGVAEEFEPLTLLDRLLPVYAEVLGDLRAAGAEWVQLDEPALVQDRTPAELNAAARAYRDLGALTDRPKLLIASYFDRLGEALPVLAKAPVEGLALDFTEAAAANLDDLAAVGGLPGKRLVAGVVNGRNIWINDHEKSLATLATLLGLAGRVDVAASCSLLHVPLDTAPERDLDPRILRWLAFARQKTAEIVTLAKGLAQGTGAVAAEIAANRAALASRADSPLTRDPAVRARTAAVTEADARRPQPYPERAVAQRERLRLPLLPTTTIGSFPQTGEVRAARADLRAGRIGAAGYEERIAAEIAEVIAFQEKAGIDVLVHGEAERNDMVQYFAEQLTGYLATQHGWVQSYGTRYVRPPVLAGDISRPAPMTVGWTTYAQSLTERPVKGMLTGPVTMLAWSFVRDDQPLGETAAQVALALRDEVADLEAAGTSVIQVDEPALRETLPLRAADRPAYLEWATRAFRLTTGGVAPATQIHTHMCYAEFGDIVQAIDDLDADVISLEAARSHMEVAHELAAHGYPREAGPGVYDIHSPRVPGAEEAAALLREGLAAIPAERLWVNPDCGLKTRGWPETRASLENLVAAARTVRAALDAS
>NZ_CP047147.1|WP_159313302.1|5917360_5917807_+|ATP-binding-protein
MPRLTTRVRPTGPPGYSETLPREPESAVLARRLVRTSCCAWGLHTLAADGAVIITELVANSVRHARRESIRVTVERPGECRVRLGVVDFSKARPVRGTAGPEDEAGRGLVLVEALAAEWGTELLPWGKRVWAELGGAGTPGETPRPAM
>NZ_CP047147.1|WP_159313301.1|5914120_5915317_+|NAD(P)-binding-protein
MTTTTTAIATGETTSTTPVPEHHPLLVVGAGLGGLTLARVLALHGVRCTVLDLDPARDARPQGGMLDLHEDAAQRALREAGLYEEFRRLVQPGGEATRVLDRHATVHHADDAEGGRPEVHRAALRDLLLDSLPAGTVRWGAKVTAVTTLGGGRHEVTLADGTRLTTGLLVGADGAWSRVRPLLSEAVPAYTGISFVEADLTDADRRHPRAAALVGSGLLFALDQGKGFLAHREPGARLHTCVALRCPAGLLDTLDLADPAAARRQVLAHFDGWDADLCSLLADGDGPLVARPIHALPAGHRWERVPGVTLLGDAAHLMSPFAGEGANLAMLDGAELATALLAHPDDPEHALTTYETALFPRSERSARDSAESLELCFGPDAAGRLAAMMGGGWGDEGV
>NZ_CP047147.1|WP_003951460.1|5911262_5913464_-|discoidin-domain-containing-protein
MLTTSLRPPRPGGGPRPRARYRRSVSALVAGALTATALVMLPATSAQAAPALVSQNKNVTASSQENYGTPATFAVDGDTSTRWSSADSDAQWLQVDLGAKTAVSKVVLQWEAAYAKGYKIELSEDGESWRTAHSTTDGKGGTETVPLSGDARYVRLTGTERATQYGYSLWEFQVYGETGTGVGPIEAGGDLGPNVHVFDPSTPDIQGTVDQIFKEQESAQFGEGRHALMFKPGTYNDLNVQIGFYTGISGLGLSPDDTHFNGDVTVDAGWFDGNATQNFWRSAENLSLSPVNGTNRWAVSQAAPFRRMHVRGGLNLAPDGYGWASGGYIADSKIDGTVGPYSQQQWYTRDSSVGGWTNGVWNMVFSGVQGAPAQGFPEPPYTTLETTPISREKPFLYLDGDDYKVFVPEKRTNARGVSWEGNQQGESLSLDQFYVVKPGATAATINAAVDQGLHLLFTPGIYHVDEAINVDRANTVVLGLGYATIIPDNGVTALKVGDVDGVRLAGLLIDAGTQNSETLVEIGEEGSSADHAANPTTVQDVFIRIGGAGPGKATTSLVVNSDDTIIDHTWIWRADHGEGVGWETNRADYGVQVNGDDVLATGLFVEHFNKYDVVWAGERGRTIFFQNEKAYDAPNQAAIQNGDTRGYAAYKVEDSVETHEGWGLGSYCYYNVDPSIRQEHGFQAPVKPGVKFHGLLTVSLGGNGHFDHVINQVGEPTQGSDTIPSTITEFPLP
>NZ_CP047147.1|WP_159313300.1|5908921_5911186_+|heavy-metal-translocating-P-type-ATPase
MSGRTTTAGSAEVELAIGGMTCASCAARIEKKLNRMEGVEATVNYATEKAKVSYAGPVAVGDLIATVEATGYTAREPEPPRTESGPAAGDDADARAEEELRPLRQRLVTAVVLAVPVIAMAMIPALQFTYWQWLSLALAAPVVVYAAWPFHKAAWTNLRHGAATMDTLISVGTSAAFLWSLWALFFGTAGTPGMTHPFEFTVARTDGAGNIYLEAAAGVTAFILAGRYFEARSKRRASAALRSLMELGAKEVTVLRGGREERIPAGELRTGDRFVVRPGEKVATDGTVVEGSSAIDASLLTGESVPVEVGAGDSVTGATLNAGGRLVVEATRVGADTQLARMARLVEEAQNGKAAAQRLADRISAVFVPVVIALAVATFGFWLGTGWGLTAAFTAAVAVLIIACPCALGLATPTALMVGTGRGAQLGILIKGPEVLESTRKVDTVVLDKTGTVTTGRMTLLAVHTAASTTGEEALRLAGALEHASEHPIAQAVARAAADRTGPLPAPEDFAGVPGLGVQGVVEGHAVLVGRPRLLAEWAIELPAGLERAHAGAEAAGRTAVAVAWDGEARAVLEVADAVKETSPEAIRRLRALGLTPVLLTGDNRAAAESVAREVGIDQVIAEVMPEDKAEVVKGLQAEGRTVAMVGDGVNDAAALAQADLGLAMGTGTDAAIEAGDLTLVRGDLRVAADAVRLARRTLATIKSNLFWAFAYNVAALPLAAAGLLNPMIAGAAMAFSSVFVVGNSLRLRRFKGA
>NZ_CP047147.1|WP_030766900.1|5908561_5908741_-|hypothetical-protein
MHTGVRIGLYAAGLAVAFGAAYGIGDRFGPEPAPVEHSEHQEGGAGEEHGQDHDAAPAS
>NZ_CP047147.1|WP_159313306.1|5924862_5925603_-|MerR-family-DNA-binding-transcriptional-regulator
MRQNLQTGAAGERLRPVDLARAHGLSTQAVRNYEEAGILPAAGRTPSGYRVYTPLHAAALGAFLALLPGHGHRTASEILRAVHRGAAEEAFALIAASHAQLLEDRRTLRAVESALRDLEPVPAPKGGTLFVGPLAHQLGVRPATLRKWEAAGLVRPRRDPRTGYRVYDEAAVRDARLAHQLRRGGHLLQQIAPLISQVREAGGLEPLADTLHTWHARLTGRGRALLAGAAELEAYLRAREEPARDA
>NZ_CP047147.1|WP_127453718.1|5925672_5926893_+|erythromycin-esterase-family-protein
MPIDLKEIAAPLDAAAVSRLLPHRPRLLALGEPTHGEDALLRLRNALFRRLVEEHGYRTITLETDCLAGLLVDAYVTSGTGTLDAALEHGFSHGWGASAANRDLVRWMRAYNARAEEEGRPAAGRLRFAGFDGPLEITHAAGPRPCLTALHAHLAAHLDPALLPCTAEELDALLGEDDRWTEPAAMTDPARSCGRSAEAARLRLLADDLTALLDQQEPHLRAAAPPGERETVRLHARTATGLLRYHRAMADPSPARMSRLCAQRDLMMAENLLALTARGPVLAHAQNAHFQRPKSAMRMWQGPVEWWSAGALVSARLGEEYAFLATALGTLRHQGVDTPPPDTVEGLLYAGLAGESHLVDARRLAAVLGDPPPAPRTSPWFGYAPLDPAHLPHLDGLVLLKDVPES
>NZ_CP047147.1|WP_003951471.1|5926983_5927928_+|DMT-family-transporter
MNTSSGTPGPWARWAAPAAASVTVVLWASAFVSIRSAGEAYSPGALALGRLLAGAAVLGAVAAVRRIGLPPRGAWPGILLSGVLWFGVYMVVLNWGEREVDAGTAALLVNIGPLLIALLGGTLLGEGLPRPLLAGVAVSFAGAVVVGLSTSGDGGASALGVVLCLLAAGSYAAGVVAQKPALRHAGALQVTTYGCLVGAVVCLPFTGTLLTELRTAPLGATLNMVYLGVFPTALAFTTWAFALSRTTAGRMGATTYAVPALVVLMSWALLGEVPAPLALAGGALCLAGVAVSRRRGPVAAARAEGRTPVPDAAE
>NZ_CP047147.1|WP_159313307.1|5928036_5928486_+|hotdog-fold-thioesterase
MTEKSSAATPEGAVAQGELTALLGTMPYAVSLGVELEAASPAETRGHLHWAPERCTIGGALHGGALMSLADAVGAVCAYLNLPPGAAGTTTVESKTNFFRALREGTARAVARPLHTGRSFVVVQTDLYDDEGRRLGQTTQTQAVLLPRT
>NZ_CP047147.1|WP_159313981.1|5928687_5929422_+|ATP-dependent-Lon-protease
MGVLATFTPQAAADAHSPWGYYGPVKGIKYKNRATIADSSRLYASTTAAKNGSGNVPSGYLGALARLYKGSTLCASNGYSYTSGPANSLSVPTLGKGCGKGTYHSYGVTKAYTGNGYKAVYTFKSPSVNHRSLTAGPAAPGHGTAPAWPKNAKGETYGSGLEATSPGNAPDLIRAYTTGGEVGYVKRAELEDEPAPASPREAVALQKRLAGADRRIAVYETDGTTVLGDFVVRRAPASALTQGH
>NZ_CP047147.1|WP_159313982.1|5929500_5931102_-|alkaline-phosphatase
MRAAARGLDRRRLLTLGGAAAALAFATNLPAAGAAQAAGFDARRLREDPFTLGVASGDPHPSSVLLWTRLAPRPFEPDSGLPAQRITVEWELARDERFRRVVRRGRETAHPEFHHSVHVQVDGLDADRVYYYRFRAGAFTSPAGRTRTTPRQGARTRELALAAVSCQAYHDGYFTAYRHLAAEDVDVVLHLGDYLYEYAVNGAGGARNYTDRVLPAVFDRETMTLEDYRLRYGLYKSDPDLIAAHAAHPFVVTWDDHETENNYAGDQPENDVDPEEFLLRRASAYRAYWENQPLRLPQRPTGPDMRLYRRLHWGDLAQFDILDTRQYRSDQAYGDGWKTPGPESEDPARTMTGGAQERWLLDGWRTSRARWNVVPQQVTFSERRNATGSAYKLSMDSWDGYPASRERLLAGAEQAGVDHLMVLTGDVHVGYGFDIKRDFSDQGSRTVGTELVATSIASGKDGADRPANWETYHAANPHLKFYNGRRGYLTVRLGEESARADFRTVSAVTAPGAPLTTAGSFVTERRSPGLKPA
>NZ_CP047147.1|WP_159313308.1|5931472_5933593_-|SDR-family-NAD(P)-dependent-oxidoreductase
MGGGSGTARAGVTAVVGGGAAGIAAVKALAEAGLPVLGLERAEALGGLWRLAGETAAYEGLRLNTSRPRTEFSDFPMPADWPDYPGRAQLLEYLEAYAERFGVTEHYRFGTTLVRARRDGDGWALELEGPDGPYTERVAHLVVANGHNHTPKLPAPRPPGRFTGTESHAHAYRVPGEFAGRRVLVVGAGNSAMDIATELTGHARRVALSTRRGVWVLPKRLLGRPSDQLNGALAAVLPWRVRQTVSQTVLRLADRRPAGPGLPVPRRGVLQDHPTLSDTVPALVAAGHLDARPGIERFEGGAVRFTDGTTEEFDHIVWCTGYRATTPFLDRDVVADPVRLLLYRHVFVPGDGSLSFVGLMQSTGSALPVVEAQARLVAAYRAGLWRLPERAVARRTALAELRAARARWGESRPHLRIDIDQYLRIVRAELARAGAGRPLAGRRVLVTGAAGTFGRAMTARFTALGAEVVGLDLTDPGDLGVPVVPCDLTEPDQARAAVAKAAGLLGGVDLLVNNAGRGGPAPAEQAPGEEVHAQLRLNLVGAWEVTAAALPHLERARGRVVFIASRMAVLPLPLAAAYGVSKRALAAYADALRLEVGTHVGVTTVYPSMVASPIHDTTRAAGLSLDGVSRPEPVEGVVDAVVAAATAPRAPRDVATTRRGRLEMAFARHAPALADRVVRRTVAARVTAGAFRDAPLAAGLVRRHRG
>NZ_CP047147.1|WP_018894712.1|5933642_5934374_-|TetR/AcrR-family-transcriptional-regulator
MRKSEDRADGGDEAAGGARARRPGRPPRGADGAPPTRERILTEATALFARGGPQGVSMRDVAARVGIDVSSVHHHFATKTALYDACFARVYEREQRALAPLVDRLAAAVATGERGEVAAAMHHLADGFVDFLQEHPHTTFLWLRRWLEPTRDSALDAAYALPIYERVERVLLGAAAGGTLLEPTPHVTVRSLVWAAHGHITALAAAERDPVAAARERYEFRAYAHRFLDRMYPAPGAEGTGGR
>NZ_CP047147.1|WP_159313309.1|5934430_5935846_+|MFS-transporter
MSLPAPSGAPGELPAPATSPGTPALVRYALGSAGMGVYVTVPGLLLLYFLTDTLGVSPWLAGLVLLVPKVVDVVLHPFVGFLSDADRVRRGSRLRLLAAGCALGPAFVALFAVPGPVADRPWAAALWVAGWFVVGNTLFAAYQVPYLATPTDMDVDYDGRTRVLSFRMVVLTLGILVGGAVAPLLVGDGEPTVAAYALMALVLGAFTLAFQLVGVGGVRRLVPPRAPAGPAAAGERRARPVRDTLADVRSVLRANPHFRVLAASYLLASTTTHLVLAGLPYYTRYELGRPGFTTVLMAAFVAPALIATPLWFRLSRRAGKQRCLLAAQSGFALGALGLAAGDRLGLAPVVAATLLLGVSFAGIQLFPFSMVPDAIREAGPGELARTGSYLGVWTATEAIGSAAGPYVYAGALALGGFVASRAGDQVTQSAQAHSAILTGFTVVPAALMVVSLLLQLRYRLDARARSGRMAG
>NZ_CP047147.1|WP_093844698.1|5935855_5937886_-|CocE/NonD-family-hydrolase
MRFVSNLPHPVKEEEHVRIPMSDGVRLSARIWRPVSSDEHPVPAVLEAIPYRKRDLSSVRDSMHHPYLAGHGYACLRVDLRGTGDSEGVLRDEYLEREQQDAEEVLAWIADQPWCDGATGMMGISWGAFAALQTAARRPPSLKAVVLASFTDDRYDDDMHYMGGAMLSDNLAEAGTMFAYATCPPDPAVVGESWRELWHERLEGSGPWVVEWLRHQRRDAYWRHASVCEDYSALQVPVLASSGWADGYSNAVTRLLENVDVPRKGLIGPWSHKFPHLGEPGPAIGYLQEVVRWWDHWLKGEENGVMDGPMLRSWMQESVPPSTSYEERPGRWVGEPSLPSPRIEPVSHPLFAHRIGHPGEAEPQGPGAGEPLTVRSPLSVGQFAGKWASYNAPPDLPYDQREEDGGSLVFDSEPLPERVEILGSPTVELEFTVDRPVAQVAARLSDVAPDGASTRVTYGVLNLTHLDGGDPEPLVPGRRYRAVVRLNGTAQAFPPGHRVRLSLSTSYWPLAWPPPEPVLLSVEPGASSLTLPVRPVGEPDEGISFEEPEAVEPLATRELAAPEQSWKVSRDLVDYRSALDIVKDSGVTRYEEIGLDVGRRAVERYDWVADDFGSVRGRSAWTMRFTRGDWSTRTETDTVLTCDEKQFHVYATLDAYEGEERVFSRNWKVSVDRDLT

Crispr_ID: NZ_CP047147_36

• CRISPR_ID: NZ_CP047147_36
• CRISPR_location: 6324039-6324125
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP047147_36

Consensus_repeat	Method
TGCCTACAGCAGCCGGGGGCGGCCCG	CRISPRCasFinder

spacers of NZ_CP047147_36

>36.1|6324065|35|NZ_CP047147|CRISPRCasFinder
TGGGGACGCCCCGGCTGCTGTAGGGGGCACACGGT

CRISPR arrays and Neighbor proteins around NZ_CP047147_36

CRISPR arrays

The CRISPR arrays of NZ_CP047147_36

>merge|NZ_CP047147|36|6324039-6324125|CRISPRCasFinder
TGCCTACAGCAGCCGGGGGCGGCCCGTGGGGACGCCCCGGCTGCTGTAGGGGGCACACGGTTGCCCACAGCAGCCGGGGGCGGCCCG

>NZ_CP047147|36|28|6324039-6324125|CRISPRCasFinder
TGCCTACAGCAGCCGGGGGCGGCCCG	TGGGGACGCCCCGGCTGCTGTAGGGGGCACACGGT
TGCCCACAGCAGCCGGGGGCGGCCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_003951846.1|6311452_6312085_+|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|316044
NZ_CP047147.1|WP_003951849.1|6315001_6315439_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159313992.1|6324151_6325024_-|peptidoglycan-DD-metalloendopeptidase-family-protein	unknown	unknown	gnl|CDD|366703
NZ_CP047147.1|WP_159313440.1|6335693_6336560_-|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|366166
NZ_CP047147.1|WP_159313436.1|6328864_6329674_-|IS5-family-transposase	unknown	unknown	gnl|CDD|379129
NZ_CP047147.1|WP_030769285.1|6317307_6317952_+|amino-acid-ABC-transporter-permease	unknown	unknown	gnl|CDD|223836
NZ_CP047147.1|WP_015506817.1|6317948_6318821_+|amino-acid-ABC-transporter-permease	unknown	unknown	gnl|CDD|223836
NZ_CP047147.1|WP_159313435.1|6328457_6328859_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_008415979.1|6312914_6314705_-|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl|CDD|238868
NZ_CP047147.1|WP_159313993.1|6330941_6332177_+|sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
NZ_CP047147.1|WP_003951850.1|6315598_6316342_+|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224051
NZ_CP047147.1|WP_159313439.1|6334746_6335652_-|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl|CDD|187572
NZ_CP047147.1|WP_159313432.1|6318872_6320468_-|CocE/NonD-family-hydrolase	unknown	unknown	gnl|CDD|334820
NZ_CP047147.1|WP_159313438.1|6332173_6332848_+|response-regulator	unknown	unknown	gnl|CDD|225107
NZ_CP047147.1|WP_107060924.1|6325622_6326381_-|transposase	unknown	unknown	gnl|CDD|372577
NZ_CP047147.1|WP_127451644.1|6316354_6317293_+|glutamate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270408
NZ_CP047147.1|WP_018469051.1|6312121_6312901_+|exodeoxyribonuclease-III	unknown	unknown	gnl|CDD|197320
NZ_CP047147.1|WP_159313437.1|6329931_6330921_+|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl|CDD|376806
NZ_CP047147.1|WP_159313433.1|6321506_6322781_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159313434.1|6326685_6327456_-|transposase	unknown	unknown	gnl|CDD|372577

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_003951846.1|6311452_6312085_+|MBL-fold-metallo-hydrolase	gnl|CDD|316044	pfam13483, Lactamase_B_3, Beta-lactamase superfamily domain. This family is part of the beta-lactamase superfamily and is related to pfam00753.	3.09376e-20
NZ_CP047147.1|WP_159313439.1|6334746_6335652_-|NAD-dependent-epimerase/dehydratase-family-protein	gnl|CDD|187572	cd05262, SDR_a7, atypical (a) SDRs, subgroup 7. This subgroup contains atypical SDRs of unknown function. Members of this subgroup have a glycine-rich NAD(P)-binding motif consensus that matches the extended SDRs, TGXXGXXG, but lacks the characteristic active site residues of the SDRs. This subgroup has basic residues (HXXXR) in place of the active site motif YXXXK, these may have a catalytic role. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	8.74396e-29
NZ_CP047147.1|WP_159313992.1|6324151_6325024_-|peptidoglycan-DD-metalloendopeptidase-family-protein	gnl|CDD|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	8.73826e-37
NZ_CP047147.1|WP_159313440.1|6335693_6336560_-|alpha/beta-fold-hydrolase	gnl|CDD|366166	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	5.04896e-24
NZ_CP047147.1|WP_159313436.1|6328864_6329674_-|IS5-family-transposase	gnl|CDD|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	1.00516e-18
NZ_CP047147.1|WP_030769285.1|6317307_6317952_+|amino-acid-ABC-transporter-permease	gnl|CDD|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	6.93308e-52
NZ_CP047147.1|WP_015506817.1|6317948_6318821_+|amino-acid-ABC-transporter-permease	gnl|CDD|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	8.34628e-58
NZ_CP047147.1|WP_008415979.1|6312914_6314705_-|SGNH/GDSL-hydrolase-family-protein	gnl|CDD|238868	cd01830, XynE_like, SGNH_hydrolase subfamily, similar to the putative arylesterase/acylhydrolase from the rumen anaerobe Prevotella bryantii XynE. The P. bryantii XynE gene is located in a xylanase gene cluster. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases.	4.9353e-78
NZ_CP047147.1|WP_003951850.1|6315598_6316342_+|amino-acid-ABC-transporter-ATP-binding-protein	gnl|CDD|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	1.29669e-151
NZ_CP047147.1|WP_159313437.1|6329931_6330921_+|CPBP-family-intramembrane-metalloprotease	gnl|CDD|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	2.65911e-08
NZ_CP047147.1|WP_159313438.1|6332173_6332848_+|response-regulator	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	2.42317e-62
NZ_CP047147.1|WP_107060924.1|6325622_6326381_-|transposase	gnl|CDD|372577	pfam13359, DDE_Tnp_4, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	3.94339e-24
NZ_CP047147.1|WP_127451644.1|6316354_6317293_+|glutamate-ABC-transporter-substrate-binding-protein	gnl|CDD|270408	cd13690, PBP2_GluB, Substrate binding domain of ABC glutamate transporter; the type 2 periplasmic binding protein fold. This group includes periplasmic glutamate-binding domain GluB from Corynebacterium efficiens and its related proteins. The GluB domain belongs to the type 2 periplasmic binding protein fold superfamily (PBP2), whose many members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	9.55056e-88
NZ_CP047147.1|WP_018469051.1|6312121_6312901_+|exodeoxyribonuclease-III	gnl|CDD|197320	cd09086, ExoIII-like_AP-endo, Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases. This subfamily includes Escherichia coli ExoIII, Neisseria meningitides NExo,and related proteins. These are ExoIII family AP endonucleases and they belong to the large EEP (exonuclease/endonuclease/phosphatase) superfamily that contains functionally diverse enzymes that share a common catalytic mechanism of cleaving phosphodiester bonds. AP endonucleases participate in the DNA base excision repair (BER) pathway. AP sites are one of the most common lesions in cellular DNA. During BER, the damaged DNA is first recognized by DNA glycosylase. AP endonucleases then catalyze the hydrolytic cleavage of the phosphodiester bond 5' to the AP site, and this is followed by the coordinated actions of DNA polymerase, deoxyribose phosphatase, and DNA ligase. If left unrepaired, AP sites block DNA replication, and have both mutagenic and cytotoxic effects. AP endonucleases can carry out a variety of excision and incision reactions on DNA, including 3'-5' exonuclease, 3'-deoxyribose phosphodiesterase, 3'-phosphatase, and occasionally, nonspecific DNase activities. Different AP endonuclease enzymes catalyze the different reactions with different efficiencies. Many organisms have two AP endonucleases, usually one is the dominant AP endonuclease, the other has weak AP endonuclease activity. For example, Neisseria meningitides Nape and NExo, and exonuclease III (ExoIII) and endonuclease IV (EndoIV) in Escherichia coli. NExo and ExoIII are found in this subfamily. NExo is the non-dominant AP endonuclease. It exhibits strong 3'-5' exonuclease and 3'-deoxyribose phosphodiesterase activities. Escherichia coli ExoIII is an active AP endonuclease, and in addition, it exhibits double strand (ds)-specific 3'-5' exonuclease, exonucleolytic RNase H, 3'-phosphomonoesterase and 3'-phosphodiesterase activities, all catalyzed by a single active site. Class II AP endonucleases have been classified into two families, designated ExoIII and EndoIV, based on their homology to the Escherichia coli enzymes ExoIII and endonuclease IV (EndoIV). This subfamily belongs to the ExoIII family; the EndoIV family belongs to a different superfamily.	2.87126e-116
NZ_CP047147.1|WP_159313993.1|6330941_6332177_+|sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	1.58522e-25
NZ_CP047147.1|WP_159313432.1|6318872_6320468_-|CocE/NonD-family-hydrolase	gnl|CDD|334820	pfam02129, Peptidase_S15, X-Pro dipeptidyl-peptidase (S15 family).	2.62868e-39
NZ_CP047147.1|WP_159313434.1|6326685_6327456_-|transposase	gnl|CDD|372577	pfam13359, DDE_Tnp_4, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	9.92454e-14

Protein sequences

>NZ_CP047147.1|WP_159313433.1|6321506_6322781_-|hypothetical-protein
MTTESEDLTSGISAQELASGTAEPSTAHTTPEDAPGTRQTSARPEQDTVSSEAPEREPAARPVDGLVRTAVTTRSVPEIVDLIRLLEQSPSGAEAAEEILRTAAVERPVDDVSDLVALLSQPPQPVDRADEAIHLAAAERPIDDVSDLVALLHRPPHDSHAGEEAVHAAATGLTVEELAQLIDRLETERVAGAETGTTPPSAALPAEPSEEEPTGSPLPDGDSASTAHTLGTATVASTTEAPTMHTPTTRPTPSLADGRRPSSRPRQAPEATTQDRQATPAAALPLWLRWTTVAALLLCGVTHFPFQPTGLPTSAYGLAVGIAVLCLLLAAGTLLRRVLPALIADILLMGSLTAAHLLAPATGPQALTSALEPGGTPAVLPAAVAGVLSLLALTLLLTRGRSREGGGPEPTAGSRNLRTRPDPR
>NZ_CP047147.1|WP_159313432.1|6318872_6320468_-|CocE/NonD-family-hydrolase
MRRPRPALTTTAACALTAALAVGTLSAPAHAAPDGPAKAQAGTSASGIRFVDITSTDGTVLKANVVTPAGSAAGDRHPVIVLPTSWAVPQIEYLAQATQLADSGYVVVSYNSRGFWQSGGEIEVAGPPDIADASAVIDWALANTPADPERVGMAGVSYGAGISLLAAAHDPRIKTVAALSGWADLIDSIYSGRTQHLQAALLLGGSGLITGRPSAELKEILGDFIGSNLDKEQQMIDWGKKRSPATHLDALNANGTAVMLGNAWGDSLFPPNQYADFYEKLTGPKRLEFRPGDHATSEATGLLGLPNDTWTSARRWFDHHLKGEENGVDREQPVRIKSRSTGAYESYPDWKSVGADSRKIDLAGTHTIRANVDSGANGGIIFLTNALDQLIRTPPMASMPLLPRRYAAVWQSERYSGGAAVRGTPEVHTTVTPTKSSGTFVAYLYDVGPLGVGKLVTHAPYTFHDREPGRPFAVDLELYSTAYDVPAGHRLAVVVDTVDPLYIEHNPSGAQLTFSSPADDPGHVSVPVREK
>NZ_CP047147.1|WP_015506817.1|6317948_6318821_+|amino-acid-ABC-transporter-permease
MTATSEQEPSALYDVPGPKARKRHRIFGVLATLAIAAILGWILYLLFDTDQFTTAKWRPFAYTGIQELLLRGLGNTLKAFAYASVLSLVLGGVLAVGRLSDHRPVRWVATVIVEFFRAMPVLVMIFFVFVALQVQALPALVTGLTLYNGSVLAEVFRSGVNSVDKGQREAAYALGMRKTQVMVQVLAPQALRAMLPAIISQLVVALKDTSLGYLITYEEFLHAGKLIASNLDYDLPFIPVVMVISPIYIGMCMLLSWFAQWVSRRQRRDPKAKAAAVTRAEPGGLLPGER
>NZ_CP047147.1|WP_030769285.1|6317307_6317952_+|amino-acid-ABC-transporter-permease
MNVLTDNFSTYGKGFLGTVELTVYASLLALVLGFLMASFRVAPVASLRFFGTAWVTVLRNTPLTLLFFAVLLGLPRFGLVLPFQLFAVLALGCYTSAFICEALRSGINTVPRGQGEAARSLGMTFGQTLSAVVLPQAFRSVIAPVGSTLIALAKNSAIAGAFSVTELLGTYRTLSELGYNIIWTFVWIALGYLIITLTISALFHLMEKRWGVAR
>NZ_CP047147.1|WP_127451644.1|6316354_6317293_+|glutamate-ABC-transporter-substrate-binding-protein
MTHTDPHRRPGRAVRLPALALLVLLALVAACGKEGSPPVKGPRADQLPDYRVDTGFSLPESPTWRKAKARGALIVGAKEDQPYLGEKDPAGGGYTGFDIEIAKMVGAHLGFAENRVRFTTIASANRETALQNGQIDYYVGTYTINDNRKRLVGFAGPYYVAGQGLLVRTDEEDIKGPEDLDGKRVCSAAGSTPYQRMQEEYPKAVLVSYDTYSICVDNLLTYQVDAVTTDDAILLGYAAKVPEELKVVGKPFSEEPYGIGVLRSDNALRLAIDDALEEGERKGYWKAAYDATLGLSGVPAPKPPAIDRYAAG
>NZ_CP047147.1|WP_003951850.1|6315598_6316342_+|amino-acid-ABC-transporter-ATP-binding-protein
MAVDPLIELHDVNKYYGDLHVLKDINLTVGRGEVVVVIGPSGSGKSTLCRTVNRLETIQSGTIRLDGQPLPEEGKALAGLRAEVGMVFQAFNLFAHKTVLQNVSLAQMKVRSRKRPEADRRSRELLERVGLAEHADKLPAQLSGGQQQRVAIARALAMDPKALLFDEPTSALDPEMITEVLEVMQQLAREGMTMVVVTHEMGFARSAANRVVFMDGGRIVEDRTPEDFFSNPESDRAKDFLSKILKH
>NZ_CP047147.1|WP_003951849.1|6315001_6315439_+|hypothetical-protein
MHIPFLDKWRERQSGPGRSAAAVFEDHPDAAADLFAECELLRSHAQVAGLELDDTPASLAALDQLLPRWRDDPEVLPWLGNDAGLYLGTVVVRTVPGARWHVWPGGRVVVRLPSGRELHVVEAGVEWAVHGAPELSQMYAEISEG
>NZ_CP047147.1|WP_008415979.1|6312914_6314705_-|SGNH/GDSL-hydrolase-family-protein
MRRQLWGPALVLALITSAASLTSAGAAEEQEPRPLRELYDNRAVSEDGRPGAADFDGQGRSLPAAALRAAGWQIGARPAVEGTRLDWPVSRPGRPDNVRAHGQRVAVEGRGDALTFLVAGTGGEATGVGTVHYRDGGHSRYRLTAPDWRTGPLATKAVALPYLNSREGRVADRPRLYVVTVPLDAGRTVESVRLPHVRGLGRSLHVFDLRVRPAAEGWTGSWSASTAGLPEVGPWRDQTLRLVVNPTKSGPTARVRLSNTFAGTPVRVGSATVAVRAEGAEPRSTPVPLTFGGQESTVLPAGAEAVSDPVGLAVEEGADLLVSLHLPGAVPSVPLHDKAVQKSYLSTPGDHAADADGAAYTGTVGTWPLLTGVDVSGGPGSVVVLGDSITEGVGTTEGANKRWTDALARRLRDQDRVPRYGVLNQGISANRVLSDRYPGDGVSSDTGGVSALHRLDRDLLSQTSVRTVVLFEGINDVRWGARADEVVDGLRQLAERARARGVRAVVTTLAPCEGESRCTPAVDAERTEINRALRADRDSFDAVLDFDRVLRDPDRPARMLPAYDSGDHLHPGEAGLQALADAVDLTVLDGRRGRTR
>NZ_CP047147.1|WP_018469051.1|6312121_6312901_+|exodeoxyribonuclease-III
MRIATWNVNSITARLPRLLAWLESSGTDVLCIQETKTTEEAFPADALAELGYESAVRATGRWNGVAIVSRTGLADVVGGLPGGPEYDGVEEPRAISATCGPVRVWSVYVPNGREVGHPHFAYKLQWLKALRDAVADDAAGGRPFAVLGDYNIAPHDTDVWDPTAFIGATHVTPEEREALAALRATGLDDVVPRPLKYDQPFTYWDYRQLGFPKNRGMRIDLVYGNDPFRAAVSDAYVDREERKGKGASDHAPVVTDLTV
>NZ_CP047147.1|WP_003951846.1|6311452_6312085_+|MBL-fold-metallo-hydrolase
MRFIKKRHSCVRLEKESGTLVIDPGGFTEPDAALGADALLVTHEHPDHFDEGRLRAALEANPAAQLWTLASVAGPMAAAFPGRVHTVGHGDTFTAAGFDVEVHGELHAVIHPDIPRVTNVGYLVDGEVFHPGDALTVPDRPVETLLLPVMAPWNKLSEVVDYVREVRPTRAYDIHDALLTDLALPVYERQIGALAGTDHHHLGPGTFTEV
>NZ_CP047147.1|WP_159313992.1|6324151_6325024_-|peptidoglycan-DD-metalloendopeptidase-family-protein
MIVPASGTITGSPSGYCRSGNSHDGFDIAGPTGASVKASADGTVRQSDKAASPGNRVVIDHAGGWETRYLHLNSRAVSTGQKVKKGQVIGTIGSTGHSTGPHLHFQVERNDVVIRDSSLLNNFRCGSAVSQGRTISYSFPGLPGGGGVVDAYPKLREGDRGDAVKSLQAHLVTAGHSVEKDGVFGAKTLAAVKAFQKKIGTGADGVVGPKTWGALLTAPAKGTKLREGSTGTEVKYLQRGLNATLGRSLDVDGKLGAASKAAVIAYQKSRGLAADGVVGPTTWSALKSGK
>NZ_CP047147.1|WP_107060924.1|6325622_6326381_-|transposase
MVFVDRLLATLVHLRHGATHDVLACWFGVDRSTITRAVGEVRPLLAERGCTVSPDVRLRSLAEVIDHLGSSGTTGIVDGTEIRVRRPAAGRKDRDKFISGKNKQNAVKSMVVTDGEGHVLWCSPARPASCADITQARQLGLVRLLADGPPVEILADAGYQGLGAQTGGRVVTPPHRKFKKNAPDWYEEMHERQRKAHSSRRIRVEHGIAHLKNWRALARHLGRREHMSDTIQAVAGLLSHQQTVDLKPTRQT
>NZ_CP047147.1|WP_159313434.1|6326685_6327456_-|transposase
MTGVITASEPSWIAPFSGLSPRQFGKLVTVLRREGADAVRKGRPWSLPLEDRALLVAAYWRTNLTMRQLAPQFGVSKSAADRIIDHLGPMLALQPRKRSAKDTVLIVDGTLVPTRDHTIAERSKNYRYSTNHQVVIDADTRLVVVVGRPLAGNRNDCKAWEESGAKAAVGKTLTIADGGYPGTGLVIPHRRERGQAGLPDWKEEHNKSHKQVRARVEHVFARMKTWKILRDCRLKGDGVHHAMLGIARMHNLALTG
>NZ_CP047147.1|WP_159313435.1|6328457_6328859_+|hypothetical-protein
MERVGAARDLVLAYVHDLNAIDEAVRVAIPSLERLADVLGLARSRQINRSGHVGTYSYTVHGAGCRFVCDNGTEVDVDFAADGGEVFDLWRLRWYGLSLPEPLDVTDQDLRSAVRSLQPLLTEVRPGWFSVAN
>NZ_CP047147.1|WP_159313436.1|6328864_6329674_-|IS5-family-transposase
MRADLVPDDLWERVAPLLPSAPERRHRYPGRLRVPDRAALAGVLYVLRTGVAWRDVPAETVGCSGVMAWRRLRDWTEAGVWPRLHAALLTELRRADLLDLDYCSMDGSHVRALKRGDHVGPSPVDRARPGSKHHLIVDRHGTPLAVTLTGGNRHDVTRLLPLLDAVPPIRGRRGRPRRKPRRLYADRGYDFDKYRRLLWKQGIKPLIARRGVAHGSGLGKVRWVVERAFAWLHQFKRLRIRYERRADLRQGLLELACSLICLRRLRASS
>NZ_CP047147.1|WP_159313437.1|6329931_6330921_+|CPBP-family-intramembrane-metalloprotease
MTTNHTESADVPADGLLRNRWRARMRARPLTFFFVLANGLSWAAWLPYILSQNGLGVWDYQFPQILGTSQVLGVLPGAYLGPIGAAFAMTALVDGRPGLRAWVRRLWRWRVAGRWYAITLLGVPVGMLVTGLAFSGGQVAAPSAAALSAIVPVLLFQIVTTGLAEEPGWRDFALPRLQSRFSPLRAAFILGPLWGAWHLPLFLTEWGGYPEASWTRPLVFLGFCVAFNVVMSWVFNRTGQSVPLSILMHVGANTFASVMWAEMFPGLDGELALIAMGSGAAVAATAIVIATRGRLGYAPSPADLSSGHGGMVPSACRAKYSQNRPMIES
>NZ_CP047147.1|WP_159313993.1|6330941_6332177_+|sensor-histidine-kinase
MTDSAAGVAAAVTALSALALLWIVTLLARDDPSLGGLPHGTVAWWVTAVTLVLQSATLVCTRHRATAALASTAALSLVLAVVFPSGLFTVTALPVLVAAFLAGLTEAWRDVRRWAPASGALVAVAYFVNSTTDGNSDGTALSMQAVLQAALVVGLPLLPASLIAAQRDTRAAQQETLAAVTRERDAKISEAIALERAAMARELHDIAAHHLSGISIMASVVARQTTSAPSEARSGALEIRRQSNAILEDLRRLVGLLRDVGPDDEEVKTLITIPGLIEAARLAGARVESDLRIAERRELGAGIGPLGQLAGYRMVQESLTNASRHAPGARCLVTVDDRSPLRLQLTVRNAPPSGAQVRPTPSGTGFGLMGMKERALLIGGDFDAGPTDDGGWETRMSIPRESEHNFPEPPT
>NZ_CP047147.1|WP_159313438.1|6332173_6332848_+|response-regulator
MIRVLLADDQPLVRAGLSALLNAEEDIAVVGVAANGAEALDMAVELAPDVACLDIRMPKMDGIDVAARLCGPDASPAVPVLILTTFDIDDYVFRALEAGVAGFLLKDSDPEEILRAIRHIVAGHGTLDRTLTRRIVAEYVQRRRLRPVTAARAIDILTARERDILLLLAQGMSNEQIAQALVVEVATVKSHLARLLPKLGVQSRLQAAVWAYQNRVVTVDDTRR
>NZ_CP047147.1|WP_159313439.1|6334746_6335652_-|NAD-dependent-epimerase/dehydratase-family-protein
MQILVIGATGYAGRRVSAALARAGHTVLGLARDTASPASRDLAVNEVTPVQGDFSKPDTWRGHLDDTDAVVHLLMDMNDPVGADQRLFTELAAAQERDGRHRHLVFTTGISSYGRTGLPLMDENTSGNPESPIGFRFALEKELAATGLAHTVVRPGFMYGGPATTSMTGQWFAAAEAGNPVFYGDTAKRWSWVHVDDLADAYVRILDNPAAVDGEVFVIADDQRLTALDMQHAAVRAAGHTGEIALESAEAGGMMQMAADQDELVTSAKAHRLLGWRPRHASFTDAPHQYYRAWKAAQPTT
>NZ_CP047147.1|WP_159313440.1|6335693_6336560_-|alpha/beta-fold-hydrolase
MPSPAPAPDGFTHADADVNGVRLHYVIGGSGPAVVLIHGWPFSWIEWRTVMPLLAEHGFTVIAPDLRGSGDSSIPAGHWTKRDEAEDLHQLMGRLGHDQAFVVGTDVGTMTAHAWAQAYPDEVARLVLSEAFLPGFGLEDHMNPATGGSWHFGFHAQSELAAMLTEGKEEAYLSGFWSMMSRGGITDADRTDLLRAYTAPDAMRGGFEHYATLVDDGRAARNSAPLAMPVLVLNGEFGLPQQVLLHGARQTARDVRADIVPAAAHTFAADNPAGAAQRLVPFFTSTPA

Crispr_ID: NZ_CP047147_37

• CRISPR_ID: NZ_CP047147_37
• CRISPR_location: 6408567-6409765
• CRISPR_type: TypeI
• Repeat_type: NA
• Spacer_info: 15 spacers
• Cas_protein_info: cas3,cas5,cas8c,cas7b

Consensus repeat of NZ_CP047147_37

Consensus_repeat	Method
GCCGCCCCGGAGGGCGACCGCCAC	CRT
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCAC	CRISPRCasFinder
GTTGCGATCCTCGGCCGCCCCGGAGGGTGACCGCCAC	PILER-CR
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCAC	CRISPRCasFinder

spacers of NZ_CP047147_37

>37.1|6408591|49|NZ_CP047147|CRT
CGTCTGGGCAGCGCGCTGGTGCGCCGAGGCGGAGTGGTTGCGATCCTCT
>37.2|6408664|52|NZ_CP047147|CRT
GCTCACCGTGTGCCCGGAGTCATCGGCCTGGGCGACGTTGCGATCCTGGGCC
>37.3|6408740|51|NZ_CP047147|CRT
CGTCACGCCGACCAGGTTCCCCGGATCGCCGCCGTGTTGTTGCGATCCTCG
>37.4|6408815|49|NZ_CP047147|CRT
GGTGTTCCGCTCGCGGCCGCGCGTCATGGCGACGTGGTTGCGATCCTCG
>37.5|6408888|49|NZ_CP047147|CRT
CCTGACCGGTGCGACGTTCGCCGGCGCCAACTACATGTTGCGATCCTCG
>37.6|6408961|50|NZ_CP047147|CRT
CCAAGATTTACTGCTCCGACCGCTGCCGGAAGGCGGCGTTGCGATCCTCG
>37.7|6409035|52|NZ_CP047147|CRT
CCGGGGCCACGGCGACCTCGCCGCGCAGCTCGCCTCGCAGTTGCGACCCTCG
>37.8|6409111|47|NZ_CP047147|CRT
GCCGTCGCCCAGCTGGCCGCCCACGCGGCCGGGGAGTGCGATCCTCG
>37.9|6409182|49|NZ_CP047147|CRT
CTCGCGCCTGACGAACTGGACCGGCACGTGGAGGATGTTGCGATCCTCG
>37.10|6409255|50|NZ_CP047147|CRT
CCCTGGCGGCTCGTACCGTCTGGCGCACGGCGGAGCGGTTGCGATCCTCG
>37.11|6409329|44|NZ_CP047147|CRT
CCGGGAGGGCGTGGGGGTCGGCCAGCGATCCAGGTTGCGATCCT
>37.12|6409397|49|NZ_CP047147|CRT
CACCATGCCGTACGCAGTACCGCCCAGCGTGAAGCGGTTGCGATCCTCG
>37.13|6409470|49|NZ_CP047147|CRT
CGCCAGCGAGGCCAGCACGAGGGGGGCCATCACGGCGTTGCGATCCTCG
>37.14|6409543|49|NZ_CP047147|CRT
GCGGCGCACCGCGTCGTCGTCGGTCTCGCCCCCGAGGTTGCGATCCTCG
>37.15|6409616|51|NZ_CP047147|CRT
GGGCGCCGCGTGACCTACGAGACCGACCTCGCCGCCGCGTTGCGATCCTCG
>37.16|6408664|36|NZ_CP047147|CRISPRCasFinder
GCTCACCGTGTGCCCGGAGTCATCGGCCTGGGCGAC
>37.17|6408737|41|NZ_CP047147|CRISPRCasFinder
CACCGTCACGCCGACCAGGTTCCCCGGATCGCCGCCGTGTT
>37.18|6408815|36|NZ_CP047147|CRISPRCasFinder,PILER-CR
GGTGTTCCGCTCGCGGCCGCGCGTCATGGCGACGTG
>37.19|6408888|36|NZ_CP047147|CRISPRCasFinder,PILER-CR
CCTGACCGGTGCGACGTTCGCCGGCGCCAACTACAT
>37.20|6408961|37|NZ_CP047147|CRISPRCasFinder
CCAAGATTTACTGCTCCGACCGCTGCCGGAAGGCGGC
>37.21|6409035|39|NZ_CP047147|CRISPRCasFinder
CCGGGGCCACGGCGACCTCGCCGCGCAGCTCGCCTCGCA
>37.22|6409111|34|NZ_CP047147|CRISPRCasFinder
GCCGTCGCCCAGCTGGCCGCCCACGCGGCCGGGG
>37.23|6409182|36|NZ_CP047147|CRISPRCasFinder
CTCGCGCCTGACGAACTGGACCGGCACGTGGAGGAT
>37.24|6409255|37|NZ_CP047147|CRISPRCasFinder
CCCTGGCGGCTCGTACCGTCTGGCGCACGGCGGAGCG
>37.25|6409470|36|NZ_CP047147|CRISPRCasFinder
CGCCAGCGAGGCCAGCACGAGGGGGGCCATCACGGC
>37.26|6409543|36|NZ_CP047147|CRISPRCasFinder
GCGGCGCACCGCGTCGTCGTCGGTCTCGCCCCCGAG
>37.27|6409616|38|NZ_CP047147|CRISPRCasFinder
GGGCGCCGCGTGACCTACGAGACCGACCTCGCCGCCGC
>37.28|6409691|37|NZ_CP047147|CRISPRCasFinder
CTGCATCCACACCCCACGAATCCCAGGTGCCCGGCAT

CRISPR arrays and Neighbor proteins around NZ_CP047147_37

CRISPR arrays

The CRISPR arrays of NZ_CP047147_37

>merge|NZ_CP047147|37|6408567-6409765|CRT,CRISPRCasFinder,PILER-CR,CRISPRCasFinder
GTCGCCCCGGAGGGCGACCGCCACCGTCTGGGCAGCGCGCTGGTGCGCCGAGGCGGAGTGGTTGCGATCCTCTACCGCCCCGAAGGACGACCGCCACGCTCACCGTGTGCCCGGAGTCATCGGCCTGGGCGACGTTGCGATCCTGGGCCGCCCCTGAGGGCGGCGACCGCCACCGTCACGCCGACCAGGTTCCCCGGATCGCCGCCGTGTTGTTGCGATCCTCGGCCGCCCCTGAGGGCGACCGCCACGGTGTTCCGCTCGCGGCCGCGCGTCATGGCGACGTGGTTGCGATCCTCGGCCGCCCCGCAGGGTGACCGCCACCCTGACCGGTGCGACGTTCGCCGGCGCCAACTACATGTTGCGATCCTCGGCCGCCCCGGAGGGTGACCGCCACCCAAGATTTACTGCTCCGACCGCTGCCGGAAGGCGGCGTTGCGATCCTCGGCGGCCCCGGAGGGCGACCGCTACCCGGGGCCACGGCGACCTCGCCGCGCAGCTCGCCTCGCAGTTGCGACCCTCGGCCGCCCCGGAGGGCGACCGCCACGCCGTCGCCCAGCTGGCCGCCCACGCGGCCGGGGAGTGCGATCCTCGGTCACCTCGGAGGGCGACCGCCACCTCGCGCCTGACGAACTGGACCGGCACGTGGAGGATGTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCACCCCTGGCGGCTCGTACCGTCTGGCGCACGGCGGAGCGGTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCACCCGGGAGGGCGTGGGGGTCGGCCAGCGATCCAGGTTGCGATCCTCGGCCGCGCGAGGGCGACCGCCACCACCATGCCGTACGCAGTACCGCCCAGCGTGAAGCGGTTGCGATCCTCGGCCGTCCCGGAGGGCGACCGCCACCGCCAGCGAGGCCAGCACGAGGGGGGCCATCACGGCGTTGCGATCCTCGGTCGCCGCGGAGGGCGACCGCCACGCGGCGCACCGCGTCGTCGTCGGTCTCGCCCCCGAGGTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCACGGGCGCCGCGTGACCTACGAGACCGACCTCGCCGCCGCGTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCGTCTGCATCCACACCCCACGAATCCCAGGTGCCCGGCATGTTGCGATCCTCGGCTGCACGGAGGGCTGCCCGTACGG

>NZ_CP047147|37|4|6408567-6409690|CRT
GTCGCCCCGGAGGGCGACCGCCAC	CGTCTGGGCAGCGCGCTGGTGCGCCGAGGCGGAGTGGTTGCGATCCTCT
ACCGCCCCGAAGGACGACCGCCAC	GCTCACCGTGTGCCCGGAGTCATCGGCCTGGGCGACGTTGCGATCCTGGGCC
GCCCCTGAGGGCGGCGACCGCCAC	CGTCACGCCGACCAGGTTCCCCGGATCGCCGCCGTGTTGTTGCGATCCTCG
GCCGCCCCTGAGGGCGACCGCCAC	GGTGTTCCGCTCGCGGCCGCGCGTCATGGCGACGTGGTTGCGATCCTCG
GCCGCCCCGCAGGGTGACCGCCAC	CCTGACCGGTGCGACGTTCGCCGGCGCCAACTACATGTTGCGATCCTCG
GCCGCCCCGGAGGGTGACCGCCAC	CCAAGATTTACTGCTCCGACCGCTGCCGGAAGGCGGCGTTGCGATCCTCG
GCGGCCCCGGAGGGCGACCGCTAC	CCGGGGCCACGGCGACCTCGCCGCGCAGCTCGCCTCGCAGTTGCGACCCTCG
GCCGCCCCGGAGGGCGACCGCCAC	GCCGTCGCCCAGCTGGCCGCCCACGCGGCCGGGGAGTGCGATCCTCG
GTCACCTCGGAGGGCGACCGCCAC	CTCGCGCCTGACGAACTGGACCGGCACGTGGAGGATGTTGCGATCCTCG
GCCGCCCCGGAGGGCGACCGCCAC	CCCTGGCGGCTCGTACCGTCTGGCGCACGGCGGAGCGGTTGCGATCCTCG
GCCGCCCCGGAGGGCGACCGCCAC	CCGGGAGGGCGTGGGGGTCGGCCAGCGATCCAGGTTGCGATCCT
CGGCCGCGCGAGGGCGACCGCCAC	CACCATGCCGTACGCAGTACCGCCCAGCGTGAAGCGGTTGCGATCCTCG
GCCGTCCCGGAGGGCGACCGCCAC	CGCCAGCGAGGCCAGCACGAGGGGGGCCATCACGGCGTTGCGATCCTCG
GTCGCCGCGGAGGGCGACCGCCAC	GCGGCGCACCGCGTCGTCGTCGGTCTCGCCCCCGAGGTTGCGATCCTCG
GCCGCCCCGGAGGGCGACCGCCAC	GGGCGCCGCGTGACCTACGAGACCGACCTCGCCGCCGCGTTGCGATCCTCG
GCCGCCCCGGAGGGCGACCGCCGT

>NZ_CP047147|37|29|6408627-6409329|CRISPRCasFinder
GTTGCGATCCTCTACCGCCCCGAAGGACGACCGCCAC	GCTCACCGTGTGCCCGGAGTCATCGGCCTGGGCGAC
GTTGCGATCCTGGGCCGCCCCTGAGGGCGGCGACCGC	CACCGTCACGCCGACCAGGTTCCCCGGATCGCCGCCGTGTT
GTTGCGATCCTCGGCCGCCCCTGAGGGCGACCGCCAC	GGTGTTCCGCTCGCGGCCGCGCGTCATGGCGACGTG
GTTGCGATCCTCGGCCGCCCCGCAGGGTGACCGCCAC	CCTGACCGGTGCGACGTTCGCCGGCGCCAACTACAT
GTTGCGATCCTCGGCCGCCCCGGAGGGTGACCGCCAC	CCAAGATTTACTGCTCCGACCGCTGCCGGAAGGCGGC
GTTGCGATCCTCGGCGGCCCCGGAGGGCGACCGCTAC	CCGGGGCCACGGCGACCTCGCCGCGCAGCTCGCCTCGCA
GTTGCGACCCTCGGCCGCCCCGGAGGGCGACCGCCAC	GCCGTCGCCCAGCTGGCCGCCCACGCGGCCGGGG
AGTGCGATCCTCGGTCACCTCGGAGGGCGACCGCCAC	CTCGCGCCTGACGAACTGGACCGGCACGTGGAGGAT
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCAC	CCCTGGCGGCTCGTACCGTCTGGCGCACGGCGGAGCG
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCACCCGGGAGGGCGTGGGGGTCGGCCAGCGATCCAGGTTGCGATCCTCGGCCGCGCGAGGGCGACCGCCACCACCATGCCGTACGCAGTACCGCCCAGCGTGAAGCGGTTGCGATCCTCGGCCGTCCCGGAGGGCGACCGCCAC	CGCCAGCGAGGCCAGCACGAGGGGGGCCATCACGGC
GTTGCGATCCTCGGTCGCCGCGGAGGGCGACCGCCAC	GCGGCGCACCGCGTCGTCGTCGGTCTCGCCCCCGAG
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCAC	GGGCGCCGCGTGACCTACGAGACCGACCTCGCCGCCGC
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCGT	CTGCATCCACACCCCACGAATCCCAGGTGCCCGGCAT


>NZ_CP047147|37|9|6408778-6408960|PILER-CR
GTTGCGATCCTCGGCCGCCCCTGAGGGCGACCGCCAC	GGTGTTCCGCTCGCGGCCGCGCGTCATGGCGACGTG
GTTGCGATCCTCGGCCGCCCCGCAGGGTGACCGCCAC	CCTGACCGGTGCGACGTTCGCCGGCGCCAACTACAT
GTTGCGATCCTCGGCCGCCCCGGAGGGTGACCGCCAC

>NZ_CP047147|37|30|6409433-6409765|CRISPRCasFinder
	GCTCACCGTGTGCCCGGAGTCATCGGCCTGGGCGAC
GTTGCGATCCTGGGCCGCCCCTGAGGGCGGCGACCGC	CACCGTCACGCCGACCAGGTTCCCCGGATCGCCGCCGTGTT
GTTGCGATCCTCGGCCGCCCCTGAGGGCGACCGCCAC	GGTGTTCCGCTCGCGGCCGCGCGTCATGGCGACGTG
GTTGCGATCCTCGGCCGCCCCGCAGGGTGACCGCCAC	CCTGACCGGTGCGACGTTCGCCGGCGCCAACTACAT
GTTGCGATCCTCGGCCGCCCCGGAGGGTGACCGCCAC	CCAAGATTTACTGCTCCGACCGCTGCCGGAAGGCGGC
GTTGCGATCCTCGGCGGCCCCGGAGGGCGACCGCTAC	CCGGGGCCACGGCGACCTCGCCGCGCAGCTCGCCTCGCA
GTTGCGACCCTCGGCCGCCCCGGAGGGCGACCGCCAC	GCCGTCGCCCAGCTGGCCGCCCACGCGGCCGGGG
AGTGCGATCCTCGGTCACCTCGGAGGGCGACCGCCAC	CTCGCGCCTGACGAACTGGACCGGCACGTGGAGGAT
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCAC	CCCTGGCGGCTCGTACCGTCTGGCGCACGGCGGAGCG
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCACCCGGGAGGGCGTGGGGGTCGGCCAGCGATCCAGGTTGCGATCCTCGGCCGCGCGAGGGCGACCGCCACCACCATGCCGTACGCAGTACCGCCCAGCGTGAAGCGGTTGCGATCCTCGGCCGTCCCGGAGGGCGACCGCCAC	CGCCAGCGAGGCCAGCACGAGGGGGGCCATCACGGC
GTTGCGATCCTCGGTCGCCGCGGAGGGCGACCGCCAC	GCGGCGCACCGCGTCGTCGTCGGTCTCGCCCCCGAG
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCAC	GGGCGCCGCGTGACCTACGAGACCGACCTCGCCGCCGC
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCGT	CTGCATCCACACCCCACGAATCCCAGGTGCCCGGCAT
GTTGCGATCCTCGGCTGCACGGAGGGCTGCCCGTACGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_159313484.1|6400928_6401357_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159313486.1|6401807_6402335_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159313485.1|6401497_6401713_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159313496.1|6421051_6421219_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159313497.1|6422082_6422514_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159313489.1|6405327_6406062_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|212491
NZ_CP047147.1|WP_159313492.1|6411384_6413643_+|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	gnl|CDD|350688
NZ_CP047147.1|WP_159313498.1|6422694_6423504_+|SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|252734
NZ_CP047147.1|WP_159313499.1|6423511_6424438_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|238045
NZ_CP047147.1|WP_121841069.1|6403995_6404211_+|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
NZ_CP047147.1|WP_159313994.1|6414399_6415092_+|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl|CDD|187534
NZ_CP047147.1|WP_129811241.1|6424527_6424770_-|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
NZ_CP047147.1|WP_121841068.1|6403104_6403989_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379262
NZ_CP047147.1|WP_159313488.1|6404595_6405207_+|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_CP047147.1|WP_159313490.1|6406870_6407635_+|transposase	unknown	unknown	gnl|CDD|372577
NZ_CP047147.1|WP_159313491.1|6407749_6408121_-|transposase	unknown	unknown	gnl|CDD|225511
NZ_CP047147.1|WP_159313495.1|6418785_6419682_+|DUF91-domain-containing-protein	unknown	unknown	gnl|CDD|226114
NZ_CP047147.1|WP_159313493.1|6415093_6416920_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	gnl|CDD|378245
NZ_CP047147.1|WP_159313487.1|6402331_6402730_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159313494.1|6416967_6417891_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl|CDD|377458

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP047147.1|WP_159313994.1|6414399_6415092_+|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	1.5e-65	215.5	0.0
NZ_CP047147.1|WP_159313493.1|6415093_6416920_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	1.5e-87	289.1	0.0
NZ_CP047147.1|WP_159313492.1|6411384_6413643_+|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	3.3e-44	146.0	0.0
NZ_CP047147.1|WP_159313494.1|6416967_6417891_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	7.1e-78	256.5	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_121841069.1|6403995_6404211_+|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	1.06199e-19
NZ_CP047147.1|WP_159313494.1|6416967_6417891_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl|CDD|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	4.58284e-109
NZ_CP047147.1|WP_129811241.1|6424527_6424770_-|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	5.83536e-17
NZ_CP047147.1|WP_159313489.1|6405327_6406062_+|SDR-family-oxidoreductase	gnl|CDD|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	1.16259e-68
NZ_CP047147.1|WP_159313492.1|6411384_6413643_+|CRISPR-associated-endonuclease-Cas3''	gnl|CDD|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	1.30009e-51
NZ_CP047147.1|WP_159313499.1|6423511_6424438_-|helix-turn-helix-domain-containing-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	0.000464657
NZ_CP047147.1|WP_159313994.1|6414399_6415092_+|type-I-C-CRISPR-associated-protein-Cas5	gnl|CDD|187534	cd09752, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	3.66721e-71
NZ_CP047147.1|WP_121841068.1|6403104_6403989_+|helix-turn-helix-domain-containing-protein	gnl|CDD|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	1.96983e-11
NZ_CP047147.1|WP_159313488.1|6404595_6405207_+|TetR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	5.98184e-10
NZ_CP047147.1|WP_159313490.1|6406870_6407635_+|transposase	gnl|CDD|372577	pfam13359, DDE_Tnp_4, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	5.67494e-25
NZ_CP047147.1|WP_159313491.1|6407749_6408121_-|transposase	gnl|CDD|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.81855e-06
NZ_CP047147.1|WP_159313498.1|6422694_6423504_+|SAM-dependent-methyltransferase	gnl|CDD|252734	pfam04672, Methyltransf_19, S-adenosyl methyltransferase. This family contains a SAM (S-adenosyl methyltransferase) domain, with a central beta sheet with 3 alpha-helices on both sides. Crystal packing analysis of the structure Structure 3giw suggests that a monomer is the solution state oligomeric form. An unidentified ligand (UNL, cyan) was found at the putative active site surrounded by the residues His57, His170, Phe171, Tyr216 and Met22. The UNL is likely to be a phenylalanine or phenylalanine-like molecule. (details derived from TOPSAN).	7.19225e-101
NZ_CP047147.1|WP_159313493.1|6415093_6416920_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl|CDD|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	1.23764e-104
NZ_CP047147.1|WP_159313495.1|6418785_6419682_+|DUF91-domain-containing-protein	gnl|CDD|226114	COG3586, COG3586, Uncharacterized conserved protein [Function unknown].	1.4272e-15

Protein sequences

>NZ_CP047147.1|WP_159313491.1|6407749_6408121_-|transposase
MDTLTMDLADPRKGVLVGRKSPYPAEFRNDAVALYRAAGGKRTYAAVAADVGVTGETLRSWVRQADEHAGRDHGREGQAAQSRDEELARLRAENGRLRKADKEWKLEREILRRAAAYFAKEMK
>NZ_CP047147.1|WP_159313490.1|6406870_6407635_+|transposase
MLIYPSGVDVSSSALRFLTQQLRRHRRTIGSRWRRLSAGRQALLTLAHLRVGHTYAQLAAGFGIGTTTAYRYVTEAVELLAALAPGLADAVRTASVKAYLLLDGTLLPIDRIAADRPFYSGKHKKHGMNVQVIADPFGQLLWASPALPGAVDDIRAAREHGIVYTLAEAGIPCWADKGYRGAGGTVRIPCWGRWETLSAGQQAVNRSHAKIRALVEKAVATLKSWRLLRKLRCSTIRITSLVQAVLTLHLTSSE
>NZ_CP047147.1|WP_159313489.1|6405327_6406062_+|SDR-family-oxidoreductase
MSSLKGKVAVVTGGNAGIGRAIAQAYHAEGARVFVTGRRQAQLDEVEAELGPQVTGIRCDVDRLDDLDSLYRTVAEQAGHIDVLVANAGIGIAAPLGEITEEQVDAMLATNVKGPLFTLQKALPHLSPGASIIFTGSSAATRPQPALPVYGATKAALRNLVRGFAHGAGVGGYRINMLSPGGTRTQGLIDLIPAEQLAAAGAGIPLGRLAEPEEIAAAAVFLASDASSYLNGSELAVDGGSAQI
>NZ_CP047147.1|WP_159313488.1|6404595_6405207_+|TetR-family-transcriptional-regulator
MPRPRKFEERDVISSASEVFTVNGLAATTLDDLVRATGLGKQSLYNAFGGKRELFLRALSEDCDEAARAVSEALQHGDASPLERIRGHMLRVAIEFSRSDSQVSLATRALVESTGEQDQLSTVTKAGIEELAGIYAHCLEDAQRSGDLPADANLTSLAMYFVAVVRGMELVGRAGVGRAALTAVALDALRVFPGGAVADPAQA
>NZ_CP047147.1|WP_121841069.1|6403995_6404211_+|DUF397-domain-containing-protein
MSITAETLRGADWFKSSYSNDQGGNCVEGARLAGRAMAVRDSKDPERGSCVFPTGAWAAFLDEMKNGAITI
>NZ_CP047147.1|WP_121841068.1|6403104_6403989_+|helix-turn-helix-domain-containing-protein
MSVDIESATPALCRLQLGSELRQLRSVAGLKSTQVVRRLIWSPSKLTRLETGENASVEPSDVMALCEIYGASEEKKAMLLGYAAVTKTKQDWWQSAAYRPVIGPGFKAFLGLEATASALHTYECEFVPGLLQTEAYIRVIHQRAHEKLGADEVDALVAVRTTRQEVLRREEAPLKFTAIINEAVLRRRVGGRKVMQDQLQHIADLADSMPNVRVQVIPFGLGSHSGMNGPFVVLHFPDRAVLKPIVYLENLADAWVTRREDTVERYSEAFTDLSALAPGHQESLSMIRTAIKEL
>NZ_CP047147.1|WP_159313487.1|6402331_6402730_-|hypothetical-protein
MASATQLVDEVLALQLSTTTRAEIESRKSALSREIDAFTRNAASGADVEGRLLRIEADSLRASAPGEPALAFSAFTYVQNAARLLRRLVAHHGEVAAQPEDGAIASRADPEPRRPSGLATVGQIQWLSGVAG
>NZ_CP047147.1|WP_159313486.1|6401807_6402335_-|hypothetical-protein
MIPAAEAARIVSAYTHRRPAEALALAPLWQTLGQHARAGGCAHRGTCPVLKVSPVVVDERGRVLMLQGRTRVRLPEAAPLPESDSFAEAAVTLARALGVGQPWMLPGVQDPILLDPRRADPEDGLRSKVAIRYLYRAHSDLCAFVAGAPQVWVPLGETDHRLADRVSSFLGERVA
>NZ_CP047147.1|WP_159313485.1|6401497_6401713_-|hypothetical-protein
MTRPRPGYDAMAVTALGVRVGDLVEHETGWLPIHDLRQIHPDGKAAVLGNLPGIWLLPPNITVMRPRAPRP
>NZ_CP047147.1|WP_159313484.1|6400928_6401357_-|hypothetical-protein
MSRNTHAAFALAAGLAHLVLKYRQHKDTVHLACTQLHARTLADMAAGPRLLTAVWEDTPEDEAVQHVLANRWMTAWSLMLRVGYTPESSLKAPLHEFMQTKYGRAFWERAGNYRAMNARDRHDRRFVKLATEAFHGADAFAD
>NZ_CP047147.1|WP_159313492.1|6411384_6413643_+|CRISPR-associated-endonuclease-Cas3''
MSGRELFAHSRNPWGVRHLLVDHLRGSAALARGFGEVFGAGEVAEFLGLVHDVGKGCCAWQERLGVVEGSGGRVGVPHKEAGTVLAARVAGRQLAAVVQGHHGGLPDQVKVKEVVAEFRGSSVVAEQAREATAAVARLVPEAVRAERIAPPSWLAGIGSAERRAEALDLYTRMVFSCVVDADYLDTAAHFAGGSPRVAGPVDMGALWERFRVRREGALAARGVSPVDGVRGRVFEEAVASGEGERGWHVLHVPTGGAKTMAGAGFALRHAVRHGLRRVVVAVPFISVTEQTAQVYRDLLDPEERSEEGPGVVLEHHSAVQLEGEGAEGAWGRLAAENWDAPVVVTTTVQLFQSMFSRKPSAMRKLHRLAGSVIVLDEVQALPDRLLVPILSVLRELVEHFGVSVVLASATQPAFWSLSQLEGVPRRMVVGDVSNLFEELRRVGYEWRMGEGVMWESVAREIAEEGGEQVLAVVNTTRDSARLHRLLTGEEPGVAGVGVPVWHLSTRMTSGHRREVIEHVRGELKAGRPVHVVSTSLIEAGVDVDFPRVYRAWAPAESLQQAAGRCNRDGRLGEGRVVVFRPAGGGMPKDLSYRAAMDATAEFFGPDLAFPDDLEALGAYYRKRWALQGAGSRAMGEEIQEMRRRWDFPAVADAFQMIDNAYAQSVVVVRPGRPEVQEAVEADIAALRSPYPCGPEPLRRLQPHMATLPRHEVVRALEAGLAEPVVGDLVVWRGFYDPVRGLDAEVLGTRRPS
>NZ_CP047147.1|WP_159313994.1|6414399_6415092_+|type-I-C-CRISPR-associated-protein-Cas5
MEVWGDAACFTRPELKTERVSYPLMTPSAARGVLEAIFWKPQFHYVVRKIEVLRPVSWMRVRRNEVKSVISAQEVKKLQADRRHRYDVEADRDQRSTLALRDVRYRIHAQIVVSPEALAGSAKFPPASEEKYREQLRRRVERGACFSEPFLGCREFSASFGKPAPGQRAVDFTDELGVMLHSIEYGPGGERYRWFRASVTDGAMDIPLEPLPEGAVAIVSPGWRADGAEG
>NZ_CP047147.1|WP_159313493.1|6415093_6416920_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MLLQRLTEYGERIAGKLPAEFYREKQIHWVLDIGEDGRQGRLLHRKVPGRQRDQVVSKPVPYVQRSGRKVPPYLLVDTAEFALGIAKTDKDGEVTDKAKDEAERRHEAYRELVLRWAETSDEPAAQAAQRFFSAGPVTFSLPEGVEAKQVEAKDTVAVMAGTRWLHELDSAQRLWAQEVRSRKGGAEERSGLCLVCGEHRALLATIPEPAKKGAVPTTGGSNEGQLISINAPAQGRDGATQLVNTPVCHQCGGRTMAVLNHLLASDRHRRRFRDDGVLLWWTRHGQDDSALAMFFDDQPDPAEIERLLDSLHTRPTPTAGGGLDTDAFYALSLGLNNARLVVRDWIDIPLPAARRNLAAWYEDHGVWDGWEGRTRYVPLWQMALSCGRWLGERYAPKSAPHGLEPELLRSALHQIRPPARALPLLLQRVHADRRIDLPRLALLRLLLNRSPNPQDHLMPQLDKDSTDPAYRWGRLFAVLESVQHAALPDINTTLRDKFFSAASTAPASTMPRLYRDAGAHLKRLRRDKPAAAHALEARLEEIYEKVCDDLPGHLDDVQQGRFIIGYSHQRAEDRARRRAAKEAKERAQRETKTADVPAQADAPQLSAS
>NZ_CP047147.1|WP_159313494.1|6416967_6417891_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MTMSDAHLDPTRKHDFVFLIEAIDSNPNGDPDNAGMPRTDLVSGQGLITDVAIKRKIRNTVALINTLEPREGREIYVEAGTALNSQHERAYTDSQVTDQKSAQEWMCRNFFDVRMFGAVMTTGKRTKQAGRVQGPVQIGFSRTIDPITPLDIGITRVTPTKEEDVKAWRERSEADDSDTKGKETEMGSKYVVPYALYRGTGHFSAPLAHRTGVTSDDLALFWRAFEIMLEHDRAAARANLALRGLYIFTHDDAFGRAPSHELFDRITVKARGDANARTFTDYGTVEIRDTDLPPGITLTTLLPRTTG
>NZ_CP047147.1|WP_159313495.1|6418785_6419682_+|DUF91-domain-containing-protein
MSGLKLFRADATNGGMIEVMPRLAGIEAEVQGLVEAHMETLLGVRFLASEYGTGPVHGGRIDSLGLDENGSPVIVEYKRGVDAGVIAQGLFYLTWLMDHRAEFEHLVRDRLGGPAAAQVLWSSPRLICIAGDFTRYDVHAVREHRRSIDLVRYRLFGNDLLGLETVASVSGSTQAVRRTRRRSVAQGAPDARSAGMVALADAVDEVLLGLGDGVNRVDRKTYRAYQRLRNFACLCPPQRSKLLVYLKVDPKDVDIVPGFTRDVSGLGHHGTGDLEVQLRTPRDVERAESLFRASYAAA
>NZ_CP047147.1|WP_159313496.1|6421051_6421219_+|hypothetical-protein
MVSVLGLTMRWSSLLLVVLAGGAALGNVSYETLLILAPLLLADGTAVSYHRFRSS
>NZ_CP047147.1|WP_159313497.1|6422082_6422514_+|hypothetical-protein
MFPEPPAAVEPRLPLAFTAFTARVAADYMAFATVRTGCPQDGEGVVQEALGDLVVRWEQALSSPSPAAVAWDLLSRRVNSCIPPAASSSAYRVLPRLHADVMVLRYRLGIRLTGVAELLGVDDIVVCGMVRSVTDGTWHMRSA
>NZ_CP047147.1|WP_159313498.1|6422694_6423504_+|SAM-dependent-methyltransferase
MGRDVIEPDFSKPSVARMYDYFLGGRDNYKVDRDACAELLRIAPSTRELSLVNRAFLLRAVRYLARDCGVEQFIDHGSGLPTQPNVHQVAQEVHPDARVVYVDDDPVVLGHGRMMLEEDTNATAVICQDLRKTEKIFDSPEVGRLISLNRPVAALFVSVLHCIPDTDDPWGLVRKVASRLPSGSYLVISQLASDDPQLRASITAFMRDITGNKWGEVRSVAEVARFFEGLQLVDDDTPCEVSKWRPDSEVAPRQRTQEWVEYGGIARVP
>NZ_CP047147.1|WP_159313499.1|6423511_6424438_-|helix-turn-helix-domain-containing-protein
MSNRNLSVVSGKGRPERAPVAAAKVLGNHLKRLREQAGLYQSDVVKAGVVTSTPVLSKYENARTPFQKEQLVKLVTFYAPHDPDALAEVLHLAEQAEAPEWWGEYRDVLPGHIDRLFSQEAAAREIRQFESVYVPGLLQTPDYAQALMKPAQPHSAKGLSKTDEDALRRRMFVRHHRQLLLSLPSAPDFYAVLDEAVLARAQADKHVMRGQLRHLYAVAENSRRIGIRVLPFNAPHHLRPGHASLTLLGMPPGSGDDLVYIESSNVGGSYLTERAEVEDHRQRLSKLWGAAAGKDETLAIIEKYINTQ
>NZ_CP047147.1|WP_129811241.1|6424527_6424770_-|DUF397-domain-containing-protein
MERMYKNGMPSTAATGASWVKASMSDAIGGNCVELSSLPDGSIAFRNSRDTAGPALVFTTDEFDAFLDGAKKGEFDSLTV

Crispr_ID: NZ_CP047147_38

• CRISPR_ID: NZ_CP047147_38
• CRISPR_location: 6409865-6411154
• CRISPR_type: TypeI
• Repeat_type: NA
• Spacer_info: 17 spacers
• Cas_protein_info: cas3,cas5,cas8c,cas7b

Consensus repeat of NZ_CP047147_38

Consensus_repeat	Method
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCAC	CRISPRCasFinder
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCAC	CRT
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCC	PILER-CR

spacers of NZ_CP047147_38

>38.1|6409902|37|NZ_CP047147|CRISPRCasFinder,CRT
CCGCAAGGGCAGCAGCGGTCGCGGCGGCGTTGCCGTT
>38.2|6409976|37|NZ_CP047147|CRISPRCasFinder,CRT
TCTACGCGGCGTGCGCGTAGGAGCCCTTGTCGGTGTA
>38.3|6410050|38|NZ_CP047147|CRISPRCasFinder,CRT
GGCAGGTAGGCAACCGTCGAGCCCGGCGGGACCTGGGG
>38.4|6410125|36|NZ_CP047147|CRISPRCasFinder,CRT
CCGCGCTTCGCGCGACCCGCCAGACGGGACCAGGGG
>38.5|6410198|36|NZ_CP047147|CRISPRCasFinder,CRT
CTCGGCCCGCAGGGGTCCACGGCCTGCGGCGTAGGG
>38.6|6410271|38|NZ_CP047147|CRISPRCasFinder,CRT
CCCTCGGTGATGCCCCCGGAGTGGAGCACGGTTTCGGC
>38.7|6410346|36|NZ_CP047147|CRISPRCasFinder,CRT
AGGGAAACCTCTGGCTGACGCCGCAGTCGGGCTGGC
>38.8|6410419|37|NZ_CP047147|CRISPRCasFinder,CRT
CGAACGCCTACGCGGCGTACCCCGGGCTGACCCGGGG
>38.9|6410493|37|NZ_CP047147|CRISPRCasFinder,CRT
TCGTGGACCAGGCCCGCGCGACCCACTCGGGGTCACC
>38.10|6410567|37|NZ_CP047147|CRISPRCasFinder,CRT
CGAACGCCTACGCGGCGTACCCCGGGCTGACCCGGGG
>38.11|6410641|37|NZ_CP047147|CRISPRCasFinder,CRT
TCGTGGACCAGGCCCGCGCGACCCACTCGGGGTCACC
>38.12|6410715|37|NZ_CP047147|CRISPRCasFinder,CRT
CCGTCTGGGAGACCGCGATGGCCGCCTCCACCTTGTC
>38.13|6410789|37|NZ_CP047147|CRISPRCasFinder,CRT
GCTGTCGGTTGTTTCCCGCCAGGATCTCGGCGGCCTG
>38.14|6410863|36|NZ_CP047147|CRISPRCasFinder,CRT
GTCCGGTTCGTCGGCGGCCGCGAGCTGCGCGGCGGC
>38.15|6410936|36|NZ_CP047147|CRISPRCasFinder,CRT
CGGTGCGCAGGTACGCGGCGGCCGGCTCGTCCCACG
>38.16|6411009|36|NZ_CP047147|CRISPRCasFinder,CRT
AACCCTGGGCCCGCGCTGGACGTCACCGCCATCGTG
>38.17|6411082|36|NZ_CP047147|CRISPRCasFinder,CRT
GCCGGGGTCCGCGACGGTGGCCGTTGCCAGCCGGCC
>38.18|6409974|39|NZ_CP047147|PILER-CR
ACTCTACGCGGCGTGCGCGTAGGAGCCCTTGTCGGTGTA
>38.19|6410048|40|NZ_CP047147|PILER-CR
ACGGCAGGTAGGCAACCGTCGAGCCCGGCGGGACCTGGGG
>38.20|6410123|38|NZ_CP047147|PILER-CR
ACCCGCGCTTCGCGCGACCCGCCAGACGGGACCAGGGG
>38.21|6410196|38|NZ_CP047147|PILER-CR
ACCTCGGCCCGCAGGGGTCCACGGCCTGCGGCGTAGGG
>38.22|6410269|40|NZ_CP047147|PILER-CR
ACCCCTCGGTGATGCCCCCGGAGTGGAGCACGGTTTCGGC
>38.23|6410344|38|NZ_CP047147|PILER-CR
ACAGGGAAACCTCTGGCTGACGCCGCAGTCGGGCTGGC
>38.24|6410417|39|NZ_CP047147|PILER-CR
ACCGAACGCCTACGCGGCGTACCCCGGGCTGACCCGGGG
>38.25|6410491|39|NZ_CP047147|PILER-CR
ACTCGTGGACCAGGCCCGCGCGACCCACTCGGGGTCACC
>38.26|6410565|39|NZ_CP047147|PILER-CR
ACCGAACGCCTACGCGGCGTACCCCGGGCTGACCCGGGG
>38.27|6410639|39|NZ_CP047147|PILER-CR
ACTCGTGGACCAGGCCCGCGCGACCCACTCGGGGTCACC
>38.28|6410713|39|NZ_CP047147|PILER-CR
ACCCGTCTGGGAGACCGCGATGGCCGCCTCCACCTTGTC
>38.29|6410787|39|NZ_CP047147|PILER-CR
ACGCTGTCGGTTGTTTCCCGCCAGGATCTCGGCGGCCTG
>38.30|6410861|38|NZ_CP047147|PILER-CR
ACGTCCGGTTCGTCGGCGGCCGCGAGCTGCGCGGCGGC
>38.31|6410934|38|NZ_CP047147|PILER-CR
ACCGGTGCGCAGGTACGCGGCGGCCGGCTCGTCCCACG
>38.32|6411007|38|NZ_CP047147|PILER-CR
ACAACCCTGGGCCCGCGCTGGACGTCACCGCCATCGTG
>38.33|6411080|38|NZ_CP047147|PILER-CR
ACGCCGGGGTCCGCGACGGTGGCCGTTGCCAGCCGGCC

CRISPR arrays and Neighbor proteins around NZ_CP047147_38

CRISPR arrays

The CRISPR arrays of NZ_CP047147_38

>merge|NZ_CP047147|38|6409865-6411154|CRISPRCasFinder,CRT,PILER-CR
GTTGCGATCCTCGATTGCCCCAGACGGCGACCGCCACCCGCAAGGGCAGCAGCGGTCGCGGCGGCGTTGCCGTTGTTGCGATCCTCGGCCGTCCCGGAGGGCGACCGCCACTCTACGCGGCGTGCGCGTAGGAGCCCTTGTCGGTGTAGTTGCCATCCTCGGTCGCCCCGGAGGGCGACCGCCACGGCAGGTAGGCAACCGTCGAGCCCGGCGGGACCTGGGGGTTGCGATCCTCGGCCGCCCCGGAGGACGACCGCCACCCGCGCTTCGCGCGACCCGCCAGACGGGACCAGGGGGTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCACCTCGGCCCGCAGGGGTCCACGGCCTGCGGCGTAGGGGTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCACCCCTCGGTGATGCCCCCGGAGTGGAGCACGGTTTCGGCGTTGCGATCCTCGGCCGCCCCGGAGAGCGACCGCCACAGGGAAACCTCTGGCTGACGCCGCAGTCGGGCTGGCGTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCACCGAACGCCTACGCGGCGTACCCCGGGCTGACCCGGGGGTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCACTCGTGGACCAGGCCCGCGCGACCCACTCGGGGTCACCGTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCACCGAACGCCTACGCGGCGTACCCCGGGCTGACCCGGGGGTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCACTCGTGGACCAGGCCCGCGCGACCCACTCGGGGTCACCGTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCACCCGTCTGGGAGACCGCGATGGCCGCCTCCACCTTGTCGTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCACGCTGTCGGTTGTTTCCCGCCAGGATCTCGGCGGCCTGGTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCACGTCCGGTTCGTCGGCGGCCGCGAGCTGCGCGGCGGCGTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCACCGGTGCGCAGGTACGCGGCGGCCGGCTCGTCCCACGGTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCACAACCCTGGGCCCGCGCTGGACGTCACCGCCATCGTGGTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCACGCCGGGGTCCGCGACGGTGGCCGTTGCCAGCCGGCCGTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCCC

>NZ_CP047147|38|31|6409865-6411154|CRISPRCasFinder
GTTGCGATCCTCGATTGCCCCAGACGGCGACCGCCAC	CCGCAAGGGCAGCAGCGGTCGCGGCGGCGTTGCCGTT
GTTGCGATCCTCGGCCGTCCCGGAGGGCGACCGCCAC	TCTACGCGGCGTGCGCGTAGGAGCCCTTGTCGGTGTA
GTTGCCATCCTCGGTCGCCCCGGAGGGCGACCGCCAC	GGCAGGTAGGCAACCGTCGAGCCCGGCGGGACCTGGGG
GTTGCGATCCTCGGCCGCCCCGGAGGACGACCGCCAC	CCGCGCTTCGCGCGACCCGCCAGACGGGACCAGGGG
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCAC	CTCGGCCCGCAGGGGTCCACGGCCTGCGGCGTAGGG
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCAC	CCCTCGGTGATGCCCCCGGAGTGGAGCACGGTTTCGGC
GTTGCGATCCTCGGCCGCCCCGGAGAGCGACCGCCAC	AGGGAAACCTCTGGCTGACGCCGCAGTCGGGCTGGC
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCAC	CGAACGCCTACGCGGCGTACCCCGGGCTGACCCGGGG
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCAC	TCGTGGACCAGGCCCGCGCGACCCACTCGGGGTCACC
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCAC	CGAACGCCTACGCGGCGTACCCCGGGCTGACCCGGGG
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCAC	TCGTGGACCAGGCCCGCGCGACCCACTCGGGGTCACC
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCAC	CCGTCTGGGAGACCGCGATGGCCGCCTCCACCTTGTC
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCAC	GCTGTCGGTTGTTTCCCGCCAGGATCTCGGCGGCCTG
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCAC	GTCCGGTTCGTCGGCGGCCGCGAGCTGCGCGGCGGC
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCAC	CGGTGCGCAGGTACGCGGCGGCCGGCTCGTCCCACG
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCAC	AACCCTGGGCCCGCGCTGGACGTCACCGCCATCGTG
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCAC	GCCGGGGTCCGCGACGGTGGCCGTTGCCAGCCGGCC
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCCC

>NZ_CP047147|38|5|6409865-6411154|CRT
GTTGCGATCCTCGATTGCCCCAGACGGCGACCGCCAC	CCGCAAGGGCAGCAGCGGTCGCGGCGGCGTTGCCGTT
GTTGCGATCCTCGGCCGTCCCGGAGGGCGACCGCCAC	TCTACGCGGCGTGCGCGTAGGAGCCCTTGTCGGTGTA
GTTGCCATCCTCGGTCGCCCCGGAGGGCGACCGCCAC	GGCAGGTAGGCAACCGTCGAGCCCGGCGGGACCTGGGG
GTTGCGATCCTCGGCCGCCCCGGAGGACGACCGCCAC	CCGCGCTTCGCGCGACCCGCCAGACGGGACCAGGGG
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCAC	CTCGGCCCGCAGGGGTCCACGGCCTGCGGCGTAGGG
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCAC	CCCTCGGTGATGCCCCCGGAGTGGAGCACGGTTTCGGC
GTTGCGATCCTCGGCCGCCCCGGAGAGCGACCGCCAC	AGGGAAACCTCTGGCTGACGCCGCAGTCGGGCTGGC
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCAC	CGAACGCCTACGCGGCGTACCCCGGGCTGACCCGGGG
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCAC	TCGTGGACCAGGCCCGCGCGACCCACTCGGGGTCACC
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCAC	CGAACGCCTACGCGGCGTACCCCGGGCTGACCCGGGG
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCAC	TCGTGGACCAGGCCCGCGCGACCCACTCGGGGTCACC
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCAC	CCGTCTGGGAGACCGCGATGGCCGCCTCCACCTTGTC
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCAC	GCTGTCGGTTGTTTCCCGCCAGGATCTCGGCGGCCTG
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCAC	GTCCGGTTCGTCGGCGGCCGCGAGCTGCGCGGCGGC
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCAC	CGGTGCGCAGGTACGCGGCGGCCGGCTCGTCCCACG
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCAC	AACCCTGGGCCCGCGCTGGACGTCACCGCCATCGTG
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCAC	GCCGGGGTCCGCGACGGTGGCCGTTGCCAGCCGGCC
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCCCC

>NZ_CP047147|38|10|6409939-6411152|PILER-CR
GTTGCGATCCTCGGCCGTCCCGGAGGGCGACCGCC	ACTCTACGCGGCGTGCGCGTAGGAGCCCTTGTCGGTGTA
GTTGCCATCCTCGGTCGCCCCGGAGGGCGACCGCC	ACGGCAGGTAGGCAACCGTCGAGCCCGGCGGGACCTGGGG
GTTGCGATCCTCGGCCGCCCCGGAGGACGACCGCC	ACCCGCGCTTCGCGCGACCCGCCAGACGGGACCAGGGG
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCC	ACCTCGGCCCGCAGGGGTCCACGGCCTGCGGCGTAGGG
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCC	ACCCCTCGGTGATGCCCCCGGAGTGGAGCACGGTTTCGGC
GTTGCGATCCTCGGCCGCCCCGGAGAGCGACCGCC	ACAGGGAAACCTCTGGCTGACGCCGCAGTCGGGCTGGC
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCC	ACCGAACGCCTACGCGGCGTACCCCGGGCTGACCCGGGG
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCC	ACTCGTGGACCAGGCCCGCGCGACCCACTCGGGGTCACC
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCC	ACCGAACGCCTACGCGGCGTACCCCGGGCTGACCCGGGG
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCC	ACTCGTGGACCAGGCCCGCGCGACCCACTCGGGGTCACC
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCC	ACCCGTCTGGGAGACCGCGATGGCCGCCTCCACCTTGTC
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCC	ACGCTGTCGGTTGTTTCCCGCCAGGATCTCGGCGGCCTG
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCC	ACGTCCGGTTCGTCGGCGGCCGCGAGCTGCGCGGCGGC
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCC	ACCGGTGCGCAGGTACGCGGCGGCCGGCTCGTCCCACG
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCC	ACAACCCTGGGCCCGCGCTGGACGTCACCGCCATCGTG
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCC	ACGCCGGGGTCCGCGACGGTGGCCGTTGCCAGCCGGCC
GTTGCGATCCTCGGCCGCCCCGGAGGGCGACCGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_159313484.1|6400928_6401357_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159313486.1|6401807_6402335_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159313485.1|6401497_6401713_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159313496.1|6421051_6421219_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159313497.1|6422082_6422514_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159313489.1|6405327_6406062_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|212491
NZ_CP047147.1|WP_159313492.1|6411384_6413643_+|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	gnl|CDD|350688
NZ_CP047147.1|WP_159313498.1|6422694_6423504_+|SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|252734
NZ_CP047147.1|WP_159313499.1|6423511_6424438_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|238045
NZ_CP047147.1|WP_121841069.1|6403995_6404211_+|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
NZ_CP047147.1|WP_159313994.1|6414399_6415092_+|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl|CDD|187534
NZ_CP047147.1|WP_129811241.1|6424527_6424770_-|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
NZ_CP047147.1|WP_121841068.1|6403104_6403989_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379262
NZ_CP047147.1|WP_159313488.1|6404595_6405207_+|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_CP047147.1|WP_159313490.1|6406870_6407635_+|transposase	unknown	unknown	gnl|CDD|372577
NZ_CP047147.1|WP_159313491.1|6407749_6408121_-|transposase	unknown	unknown	gnl|CDD|225511
NZ_CP047147.1|WP_159313495.1|6418785_6419682_+|DUF91-domain-containing-protein	unknown	unknown	gnl|CDD|226114
NZ_CP047147.1|WP_159313493.1|6415093_6416920_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	gnl|CDD|378245
NZ_CP047147.1|WP_159313487.1|6402331_6402730_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159313494.1|6416967_6417891_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl|CDD|377458

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP047147.1|WP_159313994.1|6414399_6415092_+|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	1.5e-65	215.5	0.0
NZ_CP047147.1|WP_159313493.1|6415093_6416920_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	1.5e-87	289.1	0.0
NZ_CP047147.1|WP_159313492.1|6411384_6413643_+|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	3.3e-44	146.0	0.0
NZ_CP047147.1|WP_159313494.1|6416967_6417891_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	7.1e-78	256.5	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_121841069.1|6403995_6404211_+|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	1.06199e-19
NZ_CP047147.1|WP_159313494.1|6416967_6417891_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl|CDD|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	4.58284e-109
NZ_CP047147.1|WP_129811241.1|6424527_6424770_-|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	5.83536e-17
NZ_CP047147.1|WP_159313489.1|6405327_6406062_+|SDR-family-oxidoreductase	gnl|CDD|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	1.16259e-68
NZ_CP047147.1|WP_159313492.1|6411384_6413643_+|CRISPR-associated-endonuclease-Cas3''	gnl|CDD|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	1.30009e-51
NZ_CP047147.1|WP_159313499.1|6423511_6424438_-|helix-turn-helix-domain-containing-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	0.000464657
NZ_CP047147.1|WP_159313994.1|6414399_6415092_+|type-I-C-CRISPR-associated-protein-Cas5	gnl|CDD|187534	cd09752, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	3.66721e-71
NZ_CP047147.1|WP_121841068.1|6403104_6403989_+|helix-turn-helix-domain-containing-protein	gnl|CDD|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	1.96983e-11
NZ_CP047147.1|WP_159313488.1|6404595_6405207_+|TetR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	5.98184e-10
NZ_CP047147.1|WP_159313490.1|6406870_6407635_+|transposase	gnl|CDD|372577	pfam13359, DDE_Tnp_4, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	5.67494e-25
NZ_CP047147.1|WP_159313491.1|6407749_6408121_-|transposase	gnl|CDD|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.81855e-06
NZ_CP047147.1|WP_159313498.1|6422694_6423504_+|SAM-dependent-methyltransferase	gnl|CDD|252734	pfam04672, Methyltransf_19, S-adenosyl methyltransferase. This family contains a SAM (S-adenosyl methyltransferase) domain, with a central beta sheet with 3 alpha-helices on both sides. Crystal packing analysis of the structure Structure 3giw suggests that a monomer is the solution state oligomeric form. An unidentified ligand (UNL, cyan) was found at the putative active site surrounded by the residues His57, His170, Phe171, Tyr216 and Met22. The UNL is likely to be a phenylalanine or phenylalanine-like molecule. (details derived from TOPSAN).	7.19225e-101
NZ_CP047147.1|WP_159313493.1|6415093_6416920_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl|CDD|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	1.23764e-104
NZ_CP047147.1|WP_159313495.1|6418785_6419682_+|DUF91-domain-containing-protein	gnl|CDD|226114	COG3586, COG3586, Uncharacterized conserved protein [Function unknown].	1.4272e-15

Protein sequences

>NZ_CP047147.1|WP_159313491.1|6407749_6408121_-|transposase
MDTLTMDLADPRKGVLVGRKSPYPAEFRNDAVALYRAAGGKRTYAAVAADVGVTGETLRSWVRQADEHAGRDHGREGQAAQSRDEELARLRAENGRLRKADKEWKLEREILRRAAAYFAKEMK
>NZ_CP047147.1|WP_159313490.1|6406870_6407635_+|transposase
MLIYPSGVDVSSSALRFLTQQLRRHRRTIGSRWRRLSAGRQALLTLAHLRVGHTYAQLAAGFGIGTTTAYRYVTEAVELLAALAPGLADAVRTASVKAYLLLDGTLLPIDRIAADRPFYSGKHKKHGMNVQVIADPFGQLLWASPALPGAVDDIRAAREHGIVYTLAEAGIPCWADKGYRGAGGTVRIPCWGRWETLSAGQQAVNRSHAKIRALVEKAVATLKSWRLLRKLRCSTIRITSLVQAVLTLHLTSSE
>NZ_CP047147.1|WP_159313489.1|6405327_6406062_+|SDR-family-oxidoreductase
MSSLKGKVAVVTGGNAGIGRAIAQAYHAEGARVFVTGRRQAQLDEVEAELGPQVTGIRCDVDRLDDLDSLYRTVAEQAGHIDVLVANAGIGIAAPLGEITEEQVDAMLATNVKGPLFTLQKALPHLSPGASIIFTGSSAATRPQPALPVYGATKAALRNLVRGFAHGAGVGGYRINMLSPGGTRTQGLIDLIPAEQLAAAGAGIPLGRLAEPEEIAAAAVFLASDASSYLNGSELAVDGGSAQI
>NZ_CP047147.1|WP_159313488.1|6404595_6405207_+|TetR-family-transcriptional-regulator
MPRPRKFEERDVISSASEVFTVNGLAATTLDDLVRATGLGKQSLYNAFGGKRELFLRALSEDCDEAARAVSEALQHGDASPLERIRGHMLRVAIEFSRSDSQVSLATRALVESTGEQDQLSTVTKAGIEELAGIYAHCLEDAQRSGDLPADANLTSLAMYFVAVVRGMELVGRAGVGRAALTAVALDALRVFPGGAVADPAQA
>NZ_CP047147.1|WP_121841069.1|6403995_6404211_+|DUF397-domain-containing-protein
MSITAETLRGADWFKSSYSNDQGGNCVEGARLAGRAMAVRDSKDPERGSCVFPTGAWAAFLDEMKNGAITI
>NZ_CP047147.1|WP_121841068.1|6403104_6403989_+|helix-turn-helix-domain-containing-protein
MSVDIESATPALCRLQLGSELRQLRSVAGLKSTQVVRRLIWSPSKLTRLETGENASVEPSDVMALCEIYGASEEKKAMLLGYAAVTKTKQDWWQSAAYRPVIGPGFKAFLGLEATASALHTYECEFVPGLLQTEAYIRVIHQRAHEKLGADEVDALVAVRTTRQEVLRREEAPLKFTAIINEAVLRRRVGGRKVMQDQLQHIADLADSMPNVRVQVIPFGLGSHSGMNGPFVVLHFPDRAVLKPIVYLENLADAWVTRREDTVERYSEAFTDLSALAPGHQESLSMIRTAIKEL
>NZ_CP047147.1|WP_159313487.1|6402331_6402730_-|hypothetical-protein
MASATQLVDEVLALQLSTTTRAEIESRKSALSREIDAFTRNAASGADVEGRLLRIEADSLRASAPGEPALAFSAFTYVQNAARLLRRLVAHHGEVAAQPEDGAIASRADPEPRRPSGLATVGQIQWLSGVAG
>NZ_CP047147.1|WP_159313486.1|6401807_6402335_-|hypothetical-protein
MIPAAEAARIVSAYTHRRPAEALALAPLWQTLGQHARAGGCAHRGTCPVLKVSPVVVDERGRVLMLQGRTRVRLPEAAPLPESDSFAEAAVTLARALGVGQPWMLPGVQDPILLDPRRADPEDGLRSKVAIRYLYRAHSDLCAFVAGAPQVWVPLGETDHRLADRVSSFLGERVA
>NZ_CP047147.1|WP_159313485.1|6401497_6401713_-|hypothetical-protein
MTRPRPGYDAMAVTALGVRVGDLVEHETGWLPIHDLRQIHPDGKAAVLGNLPGIWLLPPNITVMRPRAPRP
>NZ_CP047147.1|WP_159313484.1|6400928_6401357_-|hypothetical-protein
MSRNTHAAFALAAGLAHLVLKYRQHKDTVHLACTQLHARTLADMAAGPRLLTAVWEDTPEDEAVQHVLANRWMTAWSLMLRVGYTPESSLKAPLHEFMQTKYGRAFWERAGNYRAMNARDRHDRRFVKLATEAFHGADAFAD
>NZ_CP047147.1|WP_159313492.1|6411384_6413643_+|CRISPR-associated-endonuclease-Cas3''
MSGRELFAHSRNPWGVRHLLVDHLRGSAALARGFGEVFGAGEVAEFLGLVHDVGKGCCAWQERLGVVEGSGGRVGVPHKEAGTVLAARVAGRQLAAVVQGHHGGLPDQVKVKEVVAEFRGSSVVAEQAREATAAVARLVPEAVRAERIAPPSWLAGIGSAERRAEALDLYTRMVFSCVVDADYLDTAAHFAGGSPRVAGPVDMGALWERFRVRREGALAARGVSPVDGVRGRVFEEAVASGEGERGWHVLHVPTGGAKTMAGAGFALRHAVRHGLRRVVVAVPFISVTEQTAQVYRDLLDPEERSEEGPGVVLEHHSAVQLEGEGAEGAWGRLAAENWDAPVVVTTTVQLFQSMFSRKPSAMRKLHRLAGSVIVLDEVQALPDRLLVPILSVLRELVEHFGVSVVLASATQPAFWSLSQLEGVPRRMVVGDVSNLFEELRRVGYEWRMGEGVMWESVAREIAEEGGEQVLAVVNTTRDSARLHRLLTGEEPGVAGVGVPVWHLSTRMTSGHRREVIEHVRGELKAGRPVHVVSTSLIEAGVDVDFPRVYRAWAPAESLQQAAGRCNRDGRLGEGRVVVFRPAGGGMPKDLSYRAAMDATAEFFGPDLAFPDDLEALGAYYRKRWALQGAGSRAMGEEIQEMRRRWDFPAVADAFQMIDNAYAQSVVVVRPGRPEVQEAVEADIAALRSPYPCGPEPLRRLQPHMATLPRHEVVRALEAGLAEPVVGDLVVWRGFYDPVRGLDAEVLGTRRPS
>NZ_CP047147.1|WP_159313994.1|6414399_6415092_+|type-I-C-CRISPR-associated-protein-Cas5
MEVWGDAACFTRPELKTERVSYPLMTPSAARGVLEAIFWKPQFHYVVRKIEVLRPVSWMRVRRNEVKSVISAQEVKKLQADRRHRYDVEADRDQRSTLALRDVRYRIHAQIVVSPEALAGSAKFPPASEEKYREQLRRRVERGACFSEPFLGCREFSASFGKPAPGQRAVDFTDELGVMLHSIEYGPGGERYRWFRASVTDGAMDIPLEPLPEGAVAIVSPGWRADGAEG
>NZ_CP047147.1|WP_159313493.1|6415093_6416920_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MLLQRLTEYGERIAGKLPAEFYREKQIHWVLDIGEDGRQGRLLHRKVPGRQRDQVVSKPVPYVQRSGRKVPPYLLVDTAEFALGIAKTDKDGEVTDKAKDEAERRHEAYRELVLRWAETSDEPAAQAAQRFFSAGPVTFSLPEGVEAKQVEAKDTVAVMAGTRWLHELDSAQRLWAQEVRSRKGGAEERSGLCLVCGEHRALLATIPEPAKKGAVPTTGGSNEGQLISINAPAQGRDGATQLVNTPVCHQCGGRTMAVLNHLLASDRHRRRFRDDGVLLWWTRHGQDDSALAMFFDDQPDPAEIERLLDSLHTRPTPTAGGGLDTDAFYALSLGLNNARLVVRDWIDIPLPAARRNLAAWYEDHGVWDGWEGRTRYVPLWQMALSCGRWLGERYAPKSAPHGLEPELLRSALHQIRPPARALPLLLQRVHADRRIDLPRLALLRLLLNRSPNPQDHLMPQLDKDSTDPAYRWGRLFAVLESVQHAALPDINTTLRDKFFSAASTAPASTMPRLYRDAGAHLKRLRRDKPAAAHALEARLEEIYEKVCDDLPGHLDDVQQGRFIIGYSHQRAEDRARRRAAKEAKERAQRETKTADVPAQADAPQLSAS
>NZ_CP047147.1|WP_159313494.1|6416967_6417891_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MTMSDAHLDPTRKHDFVFLIEAIDSNPNGDPDNAGMPRTDLVSGQGLITDVAIKRKIRNTVALINTLEPREGREIYVEAGTALNSQHERAYTDSQVTDQKSAQEWMCRNFFDVRMFGAVMTTGKRTKQAGRVQGPVQIGFSRTIDPITPLDIGITRVTPTKEEDVKAWRERSEADDSDTKGKETEMGSKYVVPYALYRGTGHFSAPLAHRTGVTSDDLALFWRAFEIMLEHDRAAARANLALRGLYIFTHDDAFGRAPSHELFDRITVKARGDANARTFTDYGTVEIRDTDLPPGITLTTLLPRTTG
>NZ_CP047147.1|WP_159313495.1|6418785_6419682_+|DUF91-domain-containing-protein
MSGLKLFRADATNGGMIEVMPRLAGIEAEVQGLVEAHMETLLGVRFLASEYGTGPVHGGRIDSLGLDENGSPVIVEYKRGVDAGVIAQGLFYLTWLMDHRAEFEHLVRDRLGGPAAAQVLWSSPRLICIAGDFTRYDVHAVREHRRSIDLVRYRLFGNDLLGLETVASVSGSTQAVRRTRRRSVAQGAPDARSAGMVALADAVDEVLLGLGDGVNRVDRKTYRAYQRLRNFACLCPPQRSKLLVYLKVDPKDVDIVPGFTRDVSGLGHHGTGDLEVQLRTPRDVERAESLFRASYAAA
>NZ_CP047147.1|WP_159313496.1|6421051_6421219_+|hypothetical-protein
MVSVLGLTMRWSSLLLVVLAGGAALGNVSYETLLILAPLLLADGTAVSYHRFRSS
>NZ_CP047147.1|WP_159313497.1|6422082_6422514_+|hypothetical-protein
MFPEPPAAVEPRLPLAFTAFTARVAADYMAFATVRTGCPQDGEGVVQEALGDLVVRWEQALSSPSPAAVAWDLLSRRVNSCIPPAASSSAYRVLPRLHADVMVLRYRLGIRLTGVAELLGVDDIVVCGMVRSVTDGTWHMRSA
>NZ_CP047147.1|WP_159313498.1|6422694_6423504_+|SAM-dependent-methyltransferase
MGRDVIEPDFSKPSVARMYDYFLGGRDNYKVDRDACAELLRIAPSTRELSLVNRAFLLRAVRYLARDCGVEQFIDHGSGLPTQPNVHQVAQEVHPDARVVYVDDDPVVLGHGRMMLEEDTNATAVICQDLRKTEKIFDSPEVGRLISLNRPVAALFVSVLHCIPDTDDPWGLVRKVASRLPSGSYLVISQLASDDPQLRASITAFMRDITGNKWGEVRSVAEVARFFEGLQLVDDDTPCEVSKWRPDSEVAPRQRTQEWVEYGGIARVP
>NZ_CP047147.1|WP_159313499.1|6423511_6424438_-|helix-turn-helix-domain-containing-protein
MSNRNLSVVSGKGRPERAPVAAAKVLGNHLKRLREQAGLYQSDVVKAGVVTSTPVLSKYENARTPFQKEQLVKLVTFYAPHDPDALAEVLHLAEQAEAPEWWGEYRDVLPGHIDRLFSQEAAAREIRQFESVYVPGLLQTPDYAQALMKPAQPHSAKGLSKTDEDALRRRMFVRHHRQLLLSLPSAPDFYAVLDEAVLARAQADKHVMRGQLRHLYAVAENSRRIGIRVLPFNAPHHLRPGHASLTLLGMPPGSGDDLVYIESSNVGGSYLTERAEVEDHRQRLSKLWGAAAGKDETLAIIEKYINTQ
>NZ_CP047147.1|WP_129811241.1|6424527_6424770_-|DUF397-domain-containing-protein
MERMYKNGMPSTAATGASWVKASMSDAIGGNCVELSSLPDGSIAFRNSRDTAGPALVFTTDEFDAFLDGAKKGEFDSLTV

Crispr_ID: NZ_CP047147_39

• CRISPR_ID: NZ_CP047147_39
• CRISPR_location: 6417922-6418005
• CRISPR_type: TypeI
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: cas7b,cas8c,cas5,cas3

Consensus repeat of NZ_CP047147_39

Consensus_repeat	Method
TCCGGGGCGACCGAGGATCGCAAC	CRISPRCasFinder

spacers of NZ_CP047147_39

>39.1|6417946|35|NZ_CP047147|CRISPRCasFinder
TACTTCCCGGTCCTGTCGGAAGACGGCGACGGCTC

CRISPR arrays and Neighbor proteins around NZ_CP047147_39

CRISPR arrays

The CRISPR arrays of NZ_CP047147_39

>merge|NZ_CP047147|39|6417922-6418005|CRISPRCasFinder
TTCGGGGCGGCCGAGGGTCGCAACTACTTCCCGGTCCTGTCGGAAGACGGCGACGGCTCCAAGTGGCGGTCGAGGATCGCAACC

>NZ_CP047147|39|32|6417922-6418005|CRISPRCasFinder
TTCGGGGCGGCCGAGGGTCGCAAC	TACTTCCCGGTCCTGTCGGAAGACGGCGACGGCTC
CAAGTGGCGGTCGAGGATCGCAACC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_159313502.1|6429215_6429824_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159313492.1|6411384_6413643_+|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	gnl|CDD|350688
NZ_CP047147.1|WP_159313995.1|6427765_6428395_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159313494.1|6416967_6417891_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl|CDD|377458
NZ_CP047147.1|WP_159313501.1|6426575_6427769_-|DNA-cytosine-methyltransferase	unknown	unknown	gnl|CDD|223348
NZ_CP047147.1|WP_159313496.1|6421051_6421219_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159313497.1|6422082_6422514_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159313493.1|6415093_6416920_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	gnl|CDD|378245
NZ_CP047147.1|WP_121841069.1|6403995_6404211_+|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
NZ_CP047147.1|WP_159313499.1|6423511_6424438_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|238045
NZ_CP047147.1|WP_159313994.1|6414399_6415092_+|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl|CDD|187534
NZ_CP047147.1|WP_129811241.1|6424527_6424770_-|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
NZ_CP047147.1|WP_121841068.1|6403104_6403989_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379262
NZ_CP047147.1|WP_159313488.1|6404595_6405207_+|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_CP047147.1|WP_159313490.1|6406870_6407635_+|transposase	unknown	unknown	gnl|CDD|372577
NZ_CP047147.1|WP_159313491.1|6407749_6408121_-|transposase	unknown	unknown	gnl|CDD|225511
NZ_CP047147.1|WP_159313500.1|6425463_6426576_-|replicative-DNA-helicase	unknown	unknown	gnl|CDD|366294
NZ_CP047147.1|WP_159313498.1|6422694_6423504_+|SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|252734
NZ_CP047147.1|WP_159313489.1|6405327_6406062_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|212491
NZ_CP047147.1|WP_159313495.1|6418785_6419682_+|DUF91-domain-containing-protein	unknown	unknown	gnl|CDD|226114

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP047147.1|WP_159313994.1|6414399_6415092_+|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	1.5e-65	215.5	0.0
NZ_CP047147.1|WP_159313493.1|6415093_6416920_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	1.5e-87	289.1	0.0
NZ_CP047147.1|WP_159313492.1|6411384_6413643_+|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	3.3e-44	146.0	0.0
NZ_CP047147.1|WP_159313494.1|6416967_6417891_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	7.1e-78	256.5	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_159313492.1|6411384_6413643_+|CRISPR-associated-endonuclease-Cas3''	gnl|CDD|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	1.30009e-51
NZ_CP047147.1|WP_159313494.1|6416967_6417891_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl|CDD|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	4.58284e-109
NZ_CP047147.1|WP_159313501.1|6426575_6427769_-|DNA-cytosine-methyltransferase	gnl|CDD|223348	COG0270, Dcm, Site-specific DNA methylase [DNA replication, recombination, and repair].	2.06214e-40
NZ_CP047147.1|WP_129811241.1|6424527_6424770_-|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	5.83536e-17
NZ_CP047147.1|WP_159313493.1|6415093_6416920_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl|CDD|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	1.23764e-104
NZ_CP047147.1|WP_121841069.1|6403995_6404211_+|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	1.06199e-19
NZ_CP047147.1|WP_159313499.1|6423511_6424438_-|helix-turn-helix-domain-containing-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	0.000464657
NZ_CP047147.1|WP_159313994.1|6414399_6415092_+|type-I-C-CRISPR-associated-protein-Cas5	gnl|CDD|187534	cd09752, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	3.66721e-71
NZ_CP047147.1|WP_121841068.1|6403104_6403989_+|helix-turn-helix-domain-containing-protein	gnl|CDD|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	1.96983e-11
NZ_CP047147.1|WP_159313488.1|6404595_6405207_+|TetR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	5.98184e-10
NZ_CP047147.1|WP_159313490.1|6406870_6407635_+|transposase	gnl|CDD|372577	pfam13359, DDE_Tnp_4, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	5.67494e-25
NZ_CP047147.1|WP_159313491.1|6407749_6408121_-|transposase	gnl|CDD|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.81855e-06
NZ_CP047147.1|WP_159313500.1|6425463_6426576_-|replicative-DNA-helicase	gnl|CDD|366294	pfam00772, DnaB, DnaB-like helicase N terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the Escherichia coli chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This N-terminal domain is required both for interaction with other proteins in the primosome and for DnaB helicase activity.	6.49764e-16
NZ_CP047147.1|WP_159313498.1|6422694_6423504_+|SAM-dependent-methyltransferase	gnl|CDD|252734	pfam04672, Methyltransf_19, S-adenosyl methyltransferase. This family contains a SAM (S-adenosyl methyltransferase) domain, with a central beta sheet with 3 alpha-helices on both sides. Crystal packing analysis of the structure Structure 3giw suggests that a monomer is the solution state oligomeric form. An unidentified ligand (UNL, cyan) was found at the putative active site surrounded by the residues His57, His170, Phe171, Tyr216 and Met22. The UNL is likely to be a phenylalanine or phenylalanine-like molecule. (details derived from TOPSAN).	7.19225e-101
NZ_CP047147.1|WP_159313489.1|6405327_6406062_+|SDR-family-oxidoreductase	gnl|CDD|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	1.16259e-68
NZ_CP047147.1|WP_159313495.1|6418785_6419682_+|DUF91-domain-containing-protein	gnl|CDD|226114	COG3586, COG3586, Uncharacterized conserved protein [Function unknown].	1.4272e-15

Protein sequences

>NZ_CP047147.1|WP_159313494.1|6416967_6417891_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MTMSDAHLDPTRKHDFVFLIEAIDSNPNGDPDNAGMPRTDLVSGQGLITDVAIKRKIRNTVALINTLEPREGREIYVEAGTALNSQHERAYTDSQVTDQKSAQEWMCRNFFDVRMFGAVMTTGKRTKQAGRVQGPVQIGFSRTIDPITPLDIGITRVTPTKEEDVKAWRERSEADDSDTKGKETEMGSKYVVPYALYRGTGHFSAPLAHRTGVTSDDLALFWRAFEIMLEHDRAAARANLALRGLYIFTHDDAFGRAPSHELFDRITVKARGDANARTFTDYGTVEIRDTDLPPGITLTTLLPRTTG
>NZ_CP047147.1|WP_159313493.1|6415093_6416920_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MLLQRLTEYGERIAGKLPAEFYREKQIHWVLDIGEDGRQGRLLHRKVPGRQRDQVVSKPVPYVQRSGRKVPPYLLVDTAEFALGIAKTDKDGEVTDKAKDEAERRHEAYRELVLRWAETSDEPAAQAAQRFFSAGPVTFSLPEGVEAKQVEAKDTVAVMAGTRWLHELDSAQRLWAQEVRSRKGGAEERSGLCLVCGEHRALLATIPEPAKKGAVPTTGGSNEGQLISINAPAQGRDGATQLVNTPVCHQCGGRTMAVLNHLLASDRHRRRFRDDGVLLWWTRHGQDDSALAMFFDDQPDPAEIERLLDSLHTRPTPTAGGGLDTDAFYALSLGLNNARLVVRDWIDIPLPAARRNLAAWYEDHGVWDGWEGRTRYVPLWQMALSCGRWLGERYAPKSAPHGLEPELLRSALHQIRPPARALPLLLQRVHADRRIDLPRLALLRLLLNRSPNPQDHLMPQLDKDSTDPAYRWGRLFAVLESVQHAALPDINTTLRDKFFSAASTAPASTMPRLYRDAGAHLKRLRRDKPAAAHALEARLEEIYEKVCDDLPGHLDDVQQGRFIIGYSHQRAEDRARRRAAKEAKERAQRETKTADVPAQADAPQLSAS
>NZ_CP047147.1|WP_159313994.1|6414399_6415092_+|type-I-C-CRISPR-associated-protein-Cas5
MEVWGDAACFTRPELKTERVSYPLMTPSAARGVLEAIFWKPQFHYVVRKIEVLRPVSWMRVRRNEVKSVISAQEVKKLQADRRHRYDVEADRDQRSTLALRDVRYRIHAQIVVSPEALAGSAKFPPASEEKYREQLRRRVERGACFSEPFLGCREFSASFGKPAPGQRAVDFTDELGVMLHSIEYGPGGERYRWFRASVTDGAMDIPLEPLPEGAVAIVSPGWRADGAEG
>NZ_CP047147.1|WP_159313492.1|6411384_6413643_+|CRISPR-associated-endonuclease-Cas3''
MSGRELFAHSRNPWGVRHLLVDHLRGSAALARGFGEVFGAGEVAEFLGLVHDVGKGCCAWQERLGVVEGSGGRVGVPHKEAGTVLAARVAGRQLAAVVQGHHGGLPDQVKVKEVVAEFRGSSVVAEQAREATAAVARLVPEAVRAERIAPPSWLAGIGSAERRAEALDLYTRMVFSCVVDADYLDTAAHFAGGSPRVAGPVDMGALWERFRVRREGALAARGVSPVDGVRGRVFEEAVASGEGERGWHVLHVPTGGAKTMAGAGFALRHAVRHGLRRVVVAVPFISVTEQTAQVYRDLLDPEERSEEGPGVVLEHHSAVQLEGEGAEGAWGRLAAENWDAPVVVTTTVQLFQSMFSRKPSAMRKLHRLAGSVIVLDEVQALPDRLLVPILSVLRELVEHFGVSVVLASATQPAFWSLSQLEGVPRRMVVGDVSNLFEELRRVGYEWRMGEGVMWESVAREIAEEGGEQVLAVVNTTRDSARLHRLLTGEEPGVAGVGVPVWHLSTRMTSGHRREVIEHVRGELKAGRPVHVVSTSLIEAGVDVDFPRVYRAWAPAESLQQAAGRCNRDGRLGEGRVVVFRPAGGGMPKDLSYRAAMDATAEFFGPDLAFPDDLEALGAYYRKRWALQGAGSRAMGEEIQEMRRRWDFPAVADAFQMIDNAYAQSVVVVRPGRPEVQEAVEADIAALRSPYPCGPEPLRRLQPHMATLPRHEVVRALEAGLAEPVVGDLVVWRGFYDPVRGLDAEVLGTRRPS
>NZ_CP047147.1|WP_159313491.1|6407749_6408121_-|transposase
MDTLTMDLADPRKGVLVGRKSPYPAEFRNDAVALYRAAGGKRTYAAVAADVGVTGETLRSWVRQADEHAGRDHGREGQAAQSRDEELARLRAENGRLRKADKEWKLEREILRRAAAYFAKEMK
>NZ_CP047147.1|WP_159313490.1|6406870_6407635_+|transposase
MLIYPSGVDVSSSALRFLTQQLRRHRRTIGSRWRRLSAGRQALLTLAHLRVGHTYAQLAAGFGIGTTTAYRYVTEAVELLAALAPGLADAVRTASVKAYLLLDGTLLPIDRIAADRPFYSGKHKKHGMNVQVIADPFGQLLWASPALPGAVDDIRAAREHGIVYTLAEAGIPCWADKGYRGAGGTVRIPCWGRWETLSAGQQAVNRSHAKIRALVEKAVATLKSWRLLRKLRCSTIRITSLVQAVLTLHLTSSE
>NZ_CP047147.1|WP_159313489.1|6405327_6406062_+|SDR-family-oxidoreductase
MSSLKGKVAVVTGGNAGIGRAIAQAYHAEGARVFVTGRRQAQLDEVEAELGPQVTGIRCDVDRLDDLDSLYRTVAEQAGHIDVLVANAGIGIAAPLGEITEEQVDAMLATNVKGPLFTLQKALPHLSPGASIIFTGSSAATRPQPALPVYGATKAALRNLVRGFAHGAGVGGYRINMLSPGGTRTQGLIDLIPAEQLAAAGAGIPLGRLAEPEEIAAAAVFLASDASSYLNGSELAVDGGSAQI
>NZ_CP047147.1|WP_159313488.1|6404595_6405207_+|TetR-family-transcriptional-regulator
MPRPRKFEERDVISSASEVFTVNGLAATTLDDLVRATGLGKQSLYNAFGGKRELFLRALSEDCDEAARAVSEALQHGDASPLERIRGHMLRVAIEFSRSDSQVSLATRALVESTGEQDQLSTVTKAGIEELAGIYAHCLEDAQRSGDLPADANLTSLAMYFVAVVRGMELVGRAGVGRAALTAVALDALRVFPGGAVADPAQA
>NZ_CP047147.1|WP_121841069.1|6403995_6404211_+|DUF397-domain-containing-protein
MSITAETLRGADWFKSSYSNDQGGNCVEGARLAGRAMAVRDSKDPERGSCVFPTGAWAAFLDEMKNGAITI
>NZ_CP047147.1|WP_121841068.1|6403104_6403989_+|helix-turn-helix-domain-containing-protein
MSVDIESATPALCRLQLGSELRQLRSVAGLKSTQVVRRLIWSPSKLTRLETGENASVEPSDVMALCEIYGASEEKKAMLLGYAAVTKTKQDWWQSAAYRPVIGPGFKAFLGLEATASALHTYECEFVPGLLQTEAYIRVIHQRAHEKLGADEVDALVAVRTTRQEVLRREEAPLKFTAIINEAVLRRRVGGRKVMQDQLQHIADLADSMPNVRVQVIPFGLGSHSGMNGPFVVLHFPDRAVLKPIVYLENLADAWVTRREDTVERYSEAFTDLSALAPGHQESLSMIRTAIKEL
>NZ_CP047147.1|WP_159313495.1|6418785_6419682_+|DUF91-domain-containing-protein
MSGLKLFRADATNGGMIEVMPRLAGIEAEVQGLVEAHMETLLGVRFLASEYGTGPVHGGRIDSLGLDENGSPVIVEYKRGVDAGVIAQGLFYLTWLMDHRAEFEHLVRDRLGGPAAAQVLWSSPRLICIAGDFTRYDVHAVREHRRSIDLVRYRLFGNDLLGLETVASVSGSTQAVRRTRRRSVAQGAPDARSAGMVALADAVDEVLLGLGDGVNRVDRKTYRAYQRLRNFACLCPPQRSKLLVYLKVDPKDVDIVPGFTRDVSGLGHHGTGDLEVQLRTPRDVERAESLFRASYAAA
>NZ_CP047147.1|WP_159313496.1|6421051_6421219_+|hypothetical-protein
MVSVLGLTMRWSSLLLVVLAGGAALGNVSYETLLILAPLLLADGTAVSYHRFRSS
>NZ_CP047147.1|WP_159313497.1|6422082_6422514_+|hypothetical-protein
MFPEPPAAVEPRLPLAFTAFTARVAADYMAFATVRTGCPQDGEGVVQEALGDLVVRWEQALSSPSPAAVAWDLLSRRVNSCIPPAASSSAYRVLPRLHADVMVLRYRLGIRLTGVAELLGVDDIVVCGMVRSVTDGTWHMRSA
>NZ_CP047147.1|WP_159313498.1|6422694_6423504_+|SAM-dependent-methyltransferase
MGRDVIEPDFSKPSVARMYDYFLGGRDNYKVDRDACAELLRIAPSTRELSLVNRAFLLRAVRYLARDCGVEQFIDHGSGLPTQPNVHQVAQEVHPDARVVYVDDDPVVLGHGRMMLEEDTNATAVICQDLRKTEKIFDSPEVGRLISLNRPVAALFVSVLHCIPDTDDPWGLVRKVASRLPSGSYLVISQLASDDPQLRASITAFMRDITGNKWGEVRSVAEVARFFEGLQLVDDDTPCEVSKWRPDSEVAPRQRTQEWVEYGGIARVP
>NZ_CP047147.1|WP_159313499.1|6423511_6424438_-|helix-turn-helix-domain-containing-protein
MSNRNLSVVSGKGRPERAPVAAAKVLGNHLKRLREQAGLYQSDVVKAGVVTSTPVLSKYENARTPFQKEQLVKLVTFYAPHDPDALAEVLHLAEQAEAPEWWGEYRDVLPGHIDRLFSQEAAAREIRQFESVYVPGLLQTPDYAQALMKPAQPHSAKGLSKTDEDALRRRMFVRHHRQLLLSLPSAPDFYAVLDEAVLARAQADKHVMRGQLRHLYAVAENSRRIGIRVLPFNAPHHLRPGHASLTLLGMPPGSGDDLVYIESSNVGGSYLTERAEVEDHRQRLSKLWGAAAGKDETLAIIEKYINTQ
>NZ_CP047147.1|WP_129811241.1|6424527_6424770_-|DUF397-domain-containing-protein
MERMYKNGMPSTAATGASWVKASMSDAIGGNCVELSSLPDGSIAFRNSRDTAGPALVFTTDEFDAFLDGAKKGEFDSLTV
>NZ_CP047147.1|WP_159313500.1|6425463_6426576_-|replicative-DNA-helicase
MPHTPEPEGLDPVPPPHLVFYVEQALLGALLLDPHRADEASGIGPDSFSTAAHAALYRAIASLPPPDAAEHAKNTRWLDRVLAAAREQARGLSPSYLHALIQVCPWPSHAPAYARMVEAEHARRRLQAAAERLVHTVHDASLAHPVKAALTEADALTKVVDDIAHRFPPRAGVMPHTIKTAPPATPYPVGAVEEERMLLATATAYPSEIASVRWLLPDDLVLPLHAGLWQCLVALDRRNEPVDPVTVLWEAQQRGFMDGGNEPGEVLRMLAEPAGSVEHWGERALQRSLLATAEHTARRIEAYVGDRANSPFQLVVGARRALADVSSVRVRWRHSTKAVPPLQRRPEVTTRARPPTTRAARTVRSTRATR
>NZ_CP047147.1|WP_159313501.1|6426575_6427769_-|DNA-cytosine-methyltransferase
MIVDLFAGPGGWSHALAVLGSRDIGLEWDEWACKTRAAAGQLTVRTDVAAYPVEPFLGKTTGLIASPPCQAWSRAGKRLGLLDQPLVHEAVAKLAAGQDPRERLLAACRDPRSLLAAEPMRYLRALHTVGQPEWVVMEEVPDTLPLWKQYASVLRGFGYSVWTGLLNSADFGVPQTRTRAILLASRVRTAQPPEPTHARNAEPESLFGPGRRQWTSMAEALGWGATDRPVPTVCAGGGPGGGPEPFPSGSRQSLANARNRGTWTPHPNAAPHPVAPYAEGGLSWSLRSNNQANATTRLLSEPAGTLFFGHRSNECTWVATPRRPGSTNDLTVVPDPIRITASEAGVLQTFPIDYPWAGNKSQQFQQIGNAVPPRLAAHLLAPHLGATSMPDDFSLAA
>NZ_CP047147.1|WP_159313995.1|6427765_6428395_-|hypothetical-protein
MTRRQCTGEYKIKPIKKKVRELLGYPYPARIPRDILVEQWVGISTDEFHRAKDADVKYMRNRHPLIELGWSRADCVKYLSSRGLADTPKSSCLGCPFHGNAQWRHIRDTSPGEWADVVAFDAAIRQGNARANAGGNRLLGQAFLHRYRVPLDEAPIDHVSAAERATLQQELGSDDDIALLEEGVPDGCSPWACRGDAEALSRDDFGLAT
>NZ_CP047147.1|WP_159313502.1|6429215_6429824_-|hypothetical-protein
MTFLDLSDVFVGSTDDGHTFVVLNRRVRGADKTLTEAGFHRQAHPGRTLYLLPPGLPEEANERVGTATDGLLAHTHDLVDLSWTTRWDPDRPDSAADLHVQFLSGTVVLTPKSTATRTLLSQHTDLASAADGSFRPQTGLDQRRQLAIVTAIETHAFMHSLKVHIDLDIPTPSEIPAGTRPRTQTATATGVPTPTTVRRRPR

Crispr_ID: NZ_CP047147_40

• CRISPR_ID: NZ_CP047147_40
• CRISPR_location: 6418127-6418441
• CRISPR_type: TypeI
• Repeat_type: NA
• Spacer_info: 4 spacers
• Cas_protein_info: cas7b,cas8c,cas5,cas3

Consensus repeat of NZ_CP047147_40

Consensus_repeat	Method
TCCGGGGCGACCGAGGATCGCAAC	CRISPRCasFinder

spacers of NZ_CP047147_40

>40.1|6418151|48|NZ_CP047147|CRISPRCasFinder
AACGGGCTGCGAGGGGTGAGCACCTGTGCGTCGAGGCGGCGGTCGCCT
>40.2|6418223|49|NZ_CP047147|CRISPRCasFinder
CGCCGGTCAGGCGGACCTGATGCAGGCCCGCGCGATGTGGCGGTCGCCT
>40.3|6418296|49|NZ_CP047147|CRISPRCasFinder
TCGAAGTTGCAGATGGCCGCGTTGATGAGCATGAAGGATGGCGGTCGCC
>40.4|6418369|49|NZ_CP047147|CRISPRCasFinder
TGGGAGAACGTCTACTTTGGCCCGCCGATCCGCACAGTGGTGGTCGTCC

CRISPR arrays and Neighbor proteins around NZ_CP047147_40

CRISPR arrays

The CRISPR arrays of NZ_CP047147_40

>merge|NZ_CP047147|40|6418127-6418441|CRISPRCasFinder
TCCGGGGCGACCGAGGATCGCAACAACGGGCTGCGAGGGGTGAGCACCTGTGCGTCGAGGCGGCGGTCGCCTTCCGGGGCGTCCGAGGATCGCAACCGCCGGTCAGGCGGACCTGATGCAGGCCCGCGCGATGTGGCGGTCGCCTTCCGGGGCGGCCGAGAATCGCAACTCGAAGTTGCAGATGGCCGCGTTGATGAGCATGAAGGATGGCGGTCGCCTCCGGGGCGTCCGAGGATCGCAACTGGGAGAACGTCTACTTTGGCCCGCCGATCCGCACAGTGGTGGTCGTCCTCGGGGGCGACCCAGGATCGCAAC

>NZ_CP047147|40|33|6418127-6418441|CRISPRCasFinder
TCCGGGGCGACCGAGGATCGCAAC	AACGGGCTGCGAGGGGTGAGCACCTGTGCGTCGAGGCGGCGGTCGCCT
TCCGGGGCGTCCGAGGATCGCAAC	CGCCGGTCAGGCGGACCTGATGCAGGCCCGCGCGATGTGGCGGTCGCCT
TCCGGGGCGGCCGAGAATCGCAAC	TCGAAGTTGCAGATGGCCGCGTTGATGAGCATGAAGGATGGCGGTCGCC
TCCGGGGCGTCCGAGGATCGCAAC	TGGGAGAACGTCTACTTTGGCCCGCCGATCCGCACAGTGGTGGTCGTCC
TCGGGGGCGACCCAGGATCGCAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_159313502.1|6429215_6429824_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159313492.1|6411384_6413643_+|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	gnl|CDD|350688
NZ_CP047147.1|WP_159313995.1|6427765_6428395_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159313494.1|6416967_6417891_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl|CDD|377458
NZ_CP047147.1|WP_159313501.1|6426575_6427769_-|DNA-cytosine-methyltransferase	unknown	unknown	gnl|CDD|223348
NZ_CP047147.1|WP_159313496.1|6421051_6421219_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159313497.1|6422082_6422514_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159313493.1|6415093_6416920_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	gnl|CDD|378245
NZ_CP047147.1|WP_121841069.1|6403995_6404211_+|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
NZ_CP047147.1|WP_159313499.1|6423511_6424438_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|238045
NZ_CP047147.1|WP_159313994.1|6414399_6415092_+|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl|CDD|187534
NZ_CP047147.1|WP_129811241.1|6424527_6424770_-|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
NZ_CP047147.1|WP_121841068.1|6403104_6403989_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379262
NZ_CP047147.1|WP_159313488.1|6404595_6405207_+|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_CP047147.1|WP_159313490.1|6406870_6407635_+|transposase	unknown	unknown	gnl|CDD|372577
NZ_CP047147.1|WP_159313491.1|6407749_6408121_-|transposase	unknown	unknown	gnl|CDD|225511
NZ_CP047147.1|WP_159313500.1|6425463_6426576_-|replicative-DNA-helicase	unknown	unknown	gnl|CDD|366294
NZ_CP047147.1|WP_159313498.1|6422694_6423504_+|SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|252734
NZ_CP047147.1|WP_159313489.1|6405327_6406062_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|212491
NZ_CP047147.1|WP_159313495.1|6418785_6419682_+|DUF91-domain-containing-protein	unknown	unknown	gnl|CDD|226114

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP047147.1|WP_159313994.1|6414399_6415092_+|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	1.5e-65	215.5	0.0
NZ_CP047147.1|WP_159313493.1|6415093_6416920_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	1.5e-87	289.1	0.0
NZ_CP047147.1|WP_159313492.1|6411384_6413643_+|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	3.3e-44	146.0	0.0
NZ_CP047147.1|WP_159313494.1|6416967_6417891_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	7.1e-78	256.5	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_159313492.1|6411384_6413643_+|CRISPR-associated-endonuclease-Cas3''	gnl|CDD|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	1.30009e-51
NZ_CP047147.1|WP_159313494.1|6416967_6417891_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl|CDD|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	4.58284e-109
NZ_CP047147.1|WP_159313501.1|6426575_6427769_-|DNA-cytosine-methyltransferase	gnl|CDD|223348	COG0270, Dcm, Site-specific DNA methylase [DNA replication, recombination, and repair].	2.06214e-40
NZ_CP047147.1|WP_129811241.1|6424527_6424770_-|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	5.83536e-17
NZ_CP047147.1|WP_159313493.1|6415093_6416920_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl|CDD|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	1.23764e-104
NZ_CP047147.1|WP_121841069.1|6403995_6404211_+|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	1.06199e-19
NZ_CP047147.1|WP_159313499.1|6423511_6424438_-|helix-turn-helix-domain-containing-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	0.000464657
NZ_CP047147.1|WP_159313994.1|6414399_6415092_+|type-I-C-CRISPR-associated-protein-Cas5	gnl|CDD|187534	cd09752, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	3.66721e-71
NZ_CP047147.1|WP_121841068.1|6403104_6403989_+|helix-turn-helix-domain-containing-protein	gnl|CDD|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	1.96983e-11
NZ_CP047147.1|WP_159313488.1|6404595_6405207_+|TetR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	5.98184e-10
NZ_CP047147.1|WP_159313490.1|6406870_6407635_+|transposase	gnl|CDD|372577	pfam13359, DDE_Tnp_4, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	5.67494e-25
NZ_CP047147.1|WP_159313491.1|6407749_6408121_-|transposase	gnl|CDD|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.81855e-06
NZ_CP047147.1|WP_159313500.1|6425463_6426576_-|replicative-DNA-helicase	gnl|CDD|366294	pfam00772, DnaB, DnaB-like helicase N terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the Escherichia coli chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This N-terminal domain is required both for interaction with other proteins in the primosome and for DnaB helicase activity.	6.49764e-16
NZ_CP047147.1|WP_159313498.1|6422694_6423504_+|SAM-dependent-methyltransferase	gnl|CDD|252734	pfam04672, Methyltransf_19, S-adenosyl methyltransferase. This family contains a SAM (S-adenosyl methyltransferase) domain, with a central beta sheet with 3 alpha-helices on both sides. Crystal packing analysis of the structure Structure 3giw suggests that a monomer is the solution state oligomeric form. An unidentified ligand (UNL, cyan) was found at the putative active site surrounded by the residues His57, His170, Phe171, Tyr216 and Met22. The UNL is likely to be a phenylalanine or phenylalanine-like molecule. (details derived from TOPSAN).	7.19225e-101
NZ_CP047147.1|WP_159313489.1|6405327_6406062_+|SDR-family-oxidoreductase	gnl|CDD|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	1.16259e-68
NZ_CP047147.1|WP_159313495.1|6418785_6419682_+|DUF91-domain-containing-protein	gnl|CDD|226114	COG3586, COG3586, Uncharacterized conserved protein [Function unknown].	1.4272e-15

Protein sequences

>NZ_CP047147.1|WP_159313494.1|6416967_6417891_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MTMSDAHLDPTRKHDFVFLIEAIDSNPNGDPDNAGMPRTDLVSGQGLITDVAIKRKIRNTVALINTLEPREGREIYVEAGTALNSQHERAYTDSQVTDQKSAQEWMCRNFFDVRMFGAVMTTGKRTKQAGRVQGPVQIGFSRTIDPITPLDIGITRVTPTKEEDVKAWRERSEADDSDTKGKETEMGSKYVVPYALYRGTGHFSAPLAHRTGVTSDDLALFWRAFEIMLEHDRAAARANLALRGLYIFTHDDAFGRAPSHELFDRITVKARGDANARTFTDYGTVEIRDTDLPPGITLTTLLPRTTG
>NZ_CP047147.1|WP_159313493.1|6415093_6416920_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MLLQRLTEYGERIAGKLPAEFYREKQIHWVLDIGEDGRQGRLLHRKVPGRQRDQVVSKPVPYVQRSGRKVPPYLLVDTAEFALGIAKTDKDGEVTDKAKDEAERRHEAYRELVLRWAETSDEPAAQAAQRFFSAGPVTFSLPEGVEAKQVEAKDTVAVMAGTRWLHELDSAQRLWAQEVRSRKGGAEERSGLCLVCGEHRALLATIPEPAKKGAVPTTGGSNEGQLISINAPAQGRDGATQLVNTPVCHQCGGRTMAVLNHLLASDRHRRRFRDDGVLLWWTRHGQDDSALAMFFDDQPDPAEIERLLDSLHTRPTPTAGGGLDTDAFYALSLGLNNARLVVRDWIDIPLPAARRNLAAWYEDHGVWDGWEGRTRYVPLWQMALSCGRWLGERYAPKSAPHGLEPELLRSALHQIRPPARALPLLLQRVHADRRIDLPRLALLRLLLNRSPNPQDHLMPQLDKDSTDPAYRWGRLFAVLESVQHAALPDINTTLRDKFFSAASTAPASTMPRLYRDAGAHLKRLRRDKPAAAHALEARLEEIYEKVCDDLPGHLDDVQQGRFIIGYSHQRAEDRARRRAAKEAKERAQRETKTADVPAQADAPQLSAS
>NZ_CP047147.1|WP_159313994.1|6414399_6415092_+|type-I-C-CRISPR-associated-protein-Cas5
MEVWGDAACFTRPELKTERVSYPLMTPSAARGVLEAIFWKPQFHYVVRKIEVLRPVSWMRVRRNEVKSVISAQEVKKLQADRRHRYDVEADRDQRSTLALRDVRYRIHAQIVVSPEALAGSAKFPPASEEKYREQLRRRVERGACFSEPFLGCREFSASFGKPAPGQRAVDFTDELGVMLHSIEYGPGGERYRWFRASVTDGAMDIPLEPLPEGAVAIVSPGWRADGAEG
>NZ_CP047147.1|WP_159313492.1|6411384_6413643_+|CRISPR-associated-endonuclease-Cas3''
MSGRELFAHSRNPWGVRHLLVDHLRGSAALARGFGEVFGAGEVAEFLGLVHDVGKGCCAWQERLGVVEGSGGRVGVPHKEAGTVLAARVAGRQLAAVVQGHHGGLPDQVKVKEVVAEFRGSSVVAEQAREATAAVARLVPEAVRAERIAPPSWLAGIGSAERRAEALDLYTRMVFSCVVDADYLDTAAHFAGGSPRVAGPVDMGALWERFRVRREGALAARGVSPVDGVRGRVFEEAVASGEGERGWHVLHVPTGGAKTMAGAGFALRHAVRHGLRRVVVAVPFISVTEQTAQVYRDLLDPEERSEEGPGVVLEHHSAVQLEGEGAEGAWGRLAAENWDAPVVVTTTVQLFQSMFSRKPSAMRKLHRLAGSVIVLDEVQALPDRLLVPILSVLRELVEHFGVSVVLASATQPAFWSLSQLEGVPRRMVVGDVSNLFEELRRVGYEWRMGEGVMWESVAREIAEEGGEQVLAVVNTTRDSARLHRLLTGEEPGVAGVGVPVWHLSTRMTSGHRREVIEHVRGELKAGRPVHVVSTSLIEAGVDVDFPRVYRAWAPAESLQQAAGRCNRDGRLGEGRVVVFRPAGGGMPKDLSYRAAMDATAEFFGPDLAFPDDLEALGAYYRKRWALQGAGSRAMGEEIQEMRRRWDFPAVADAFQMIDNAYAQSVVVVRPGRPEVQEAVEADIAALRSPYPCGPEPLRRLQPHMATLPRHEVVRALEAGLAEPVVGDLVVWRGFYDPVRGLDAEVLGTRRPS
>NZ_CP047147.1|WP_159313491.1|6407749_6408121_-|transposase
MDTLTMDLADPRKGVLVGRKSPYPAEFRNDAVALYRAAGGKRTYAAVAADVGVTGETLRSWVRQADEHAGRDHGREGQAAQSRDEELARLRAENGRLRKADKEWKLEREILRRAAAYFAKEMK
>NZ_CP047147.1|WP_159313490.1|6406870_6407635_+|transposase
MLIYPSGVDVSSSALRFLTQQLRRHRRTIGSRWRRLSAGRQALLTLAHLRVGHTYAQLAAGFGIGTTTAYRYVTEAVELLAALAPGLADAVRTASVKAYLLLDGTLLPIDRIAADRPFYSGKHKKHGMNVQVIADPFGQLLWASPALPGAVDDIRAAREHGIVYTLAEAGIPCWADKGYRGAGGTVRIPCWGRWETLSAGQQAVNRSHAKIRALVEKAVATLKSWRLLRKLRCSTIRITSLVQAVLTLHLTSSE
>NZ_CP047147.1|WP_159313489.1|6405327_6406062_+|SDR-family-oxidoreductase
MSSLKGKVAVVTGGNAGIGRAIAQAYHAEGARVFVTGRRQAQLDEVEAELGPQVTGIRCDVDRLDDLDSLYRTVAEQAGHIDVLVANAGIGIAAPLGEITEEQVDAMLATNVKGPLFTLQKALPHLSPGASIIFTGSSAATRPQPALPVYGATKAALRNLVRGFAHGAGVGGYRINMLSPGGTRTQGLIDLIPAEQLAAAGAGIPLGRLAEPEEIAAAAVFLASDASSYLNGSELAVDGGSAQI
>NZ_CP047147.1|WP_159313488.1|6404595_6405207_+|TetR-family-transcriptional-regulator
MPRPRKFEERDVISSASEVFTVNGLAATTLDDLVRATGLGKQSLYNAFGGKRELFLRALSEDCDEAARAVSEALQHGDASPLERIRGHMLRVAIEFSRSDSQVSLATRALVESTGEQDQLSTVTKAGIEELAGIYAHCLEDAQRSGDLPADANLTSLAMYFVAVVRGMELVGRAGVGRAALTAVALDALRVFPGGAVADPAQA
>NZ_CP047147.1|WP_121841069.1|6403995_6404211_+|DUF397-domain-containing-protein
MSITAETLRGADWFKSSYSNDQGGNCVEGARLAGRAMAVRDSKDPERGSCVFPTGAWAAFLDEMKNGAITI
>NZ_CP047147.1|WP_121841068.1|6403104_6403989_+|helix-turn-helix-domain-containing-protein
MSVDIESATPALCRLQLGSELRQLRSVAGLKSTQVVRRLIWSPSKLTRLETGENASVEPSDVMALCEIYGASEEKKAMLLGYAAVTKTKQDWWQSAAYRPVIGPGFKAFLGLEATASALHTYECEFVPGLLQTEAYIRVIHQRAHEKLGADEVDALVAVRTTRQEVLRREEAPLKFTAIINEAVLRRRVGGRKVMQDQLQHIADLADSMPNVRVQVIPFGLGSHSGMNGPFVVLHFPDRAVLKPIVYLENLADAWVTRREDTVERYSEAFTDLSALAPGHQESLSMIRTAIKEL
>NZ_CP047147.1|WP_159313495.1|6418785_6419682_+|DUF91-domain-containing-protein
MSGLKLFRADATNGGMIEVMPRLAGIEAEVQGLVEAHMETLLGVRFLASEYGTGPVHGGRIDSLGLDENGSPVIVEYKRGVDAGVIAQGLFYLTWLMDHRAEFEHLVRDRLGGPAAAQVLWSSPRLICIAGDFTRYDVHAVREHRRSIDLVRYRLFGNDLLGLETVASVSGSTQAVRRTRRRSVAQGAPDARSAGMVALADAVDEVLLGLGDGVNRVDRKTYRAYQRLRNFACLCPPQRSKLLVYLKVDPKDVDIVPGFTRDVSGLGHHGTGDLEVQLRTPRDVERAESLFRASYAAA
>NZ_CP047147.1|WP_159313496.1|6421051_6421219_+|hypothetical-protein
MVSVLGLTMRWSSLLLVVLAGGAALGNVSYETLLILAPLLLADGTAVSYHRFRSS
>NZ_CP047147.1|WP_159313497.1|6422082_6422514_+|hypothetical-protein
MFPEPPAAVEPRLPLAFTAFTARVAADYMAFATVRTGCPQDGEGVVQEALGDLVVRWEQALSSPSPAAVAWDLLSRRVNSCIPPAASSSAYRVLPRLHADVMVLRYRLGIRLTGVAELLGVDDIVVCGMVRSVTDGTWHMRSA
>NZ_CP047147.1|WP_159313498.1|6422694_6423504_+|SAM-dependent-methyltransferase
MGRDVIEPDFSKPSVARMYDYFLGGRDNYKVDRDACAELLRIAPSTRELSLVNRAFLLRAVRYLARDCGVEQFIDHGSGLPTQPNVHQVAQEVHPDARVVYVDDDPVVLGHGRMMLEEDTNATAVICQDLRKTEKIFDSPEVGRLISLNRPVAALFVSVLHCIPDTDDPWGLVRKVASRLPSGSYLVISQLASDDPQLRASITAFMRDITGNKWGEVRSVAEVARFFEGLQLVDDDTPCEVSKWRPDSEVAPRQRTQEWVEYGGIARVP
>NZ_CP047147.1|WP_159313499.1|6423511_6424438_-|helix-turn-helix-domain-containing-protein
MSNRNLSVVSGKGRPERAPVAAAKVLGNHLKRLREQAGLYQSDVVKAGVVTSTPVLSKYENARTPFQKEQLVKLVTFYAPHDPDALAEVLHLAEQAEAPEWWGEYRDVLPGHIDRLFSQEAAAREIRQFESVYVPGLLQTPDYAQALMKPAQPHSAKGLSKTDEDALRRRMFVRHHRQLLLSLPSAPDFYAVLDEAVLARAQADKHVMRGQLRHLYAVAENSRRIGIRVLPFNAPHHLRPGHASLTLLGMPPGSGDDLVYIESSNVGGSYLTERAEVEDHRQRLSKLWGAAAGKDETLAIIEKYINTQ
>NZ_CP047147.1|WP_129811241.1|6424527_6424770_-|DUF397-domain-containing-protein
MERMYKNGMPSTAATGASWVKASMSDAIGGNCVELSSLPDGSIAFRNSRDTAGPALVFTTDEFDAFLDGAKKGEFDSLTV
>NZ_CP047147.1|WP_159313500.1|6425463_6426576_-|replicative-DNA-helicase
MPHTPEPEGLDPVPPPHLVFYVEQALLGALLLDPHRADEASGIGPDSFSTAAHAALYRAIASLPPPDAAEHAKNTRWLDRVLAAAREQARGLSPSYLHALIQVCPWPSHAPAYARMVEAEHARRRLQAAAERLVHTVHDASLAHPVKAALTEADALTKVVDDIAHRFPPRAGVMPHTIKTAPPATPYPVGAVEEERMLLATATAYPSEIASVRWLLPDDLVLPLHAGLWQCLVALDRRNEPVDPVTVLWEAQQRGFMDGGNEPGEVLRMLAEPAGSVEHWGERALQRSLLATAEHTARRIEAYVGDRANSPFQLVVGARRALADVSSVRVRWRHSTKAVPPLQRRPEVTTRARPPTTRAARTVRSTRATR
>NZ_CP047147.1|WP_159313501.1|6426575_6427769_-|DNA-cytosine-methyltransferase
MIVDLFAGPGGWSHALAVLGSRDIGLEWDEWACKTRAAAGQLTVRTDVAAYPVEPFLGKTTGLIASPPCQAWSRAGKRLGLLDQPLVHEAVAKLAAGQDPRERLLAACRDPRSLLAAEPMRYLRALHTVGQPEWVVMEEVPDTLPLWKQYASVLRGFGYSVWTGLLNSADFGVPQTRTRAILLASRVRTAQPPEPTHARNAEPESLFGPGRRQWTSMAEALGWGATDRPVPTVCAGGGPGGGPEPFPSGSRQSLANARNRGTWTPHPNAAPHPVAPYAEGGLSWSLRSNNQANATTRLLSEPAGTLFFGHRSNECTWVATPRRPGSTNDLTVVPDPIRITASEAGVLQTFPIDYPWAGNKSQQFQQIGNAVPPRLAAHLLAPHLGATSMPDDFSLAA
>NZ_CP047147.1|WP_159313995.1|6427765_6428395_-|hypothetical-protein
MTRRQCTGEYKIKPIKKKVRELLGYPYPARIPRDILVEQWVGISTDEFHRAKDADVKYMRNRHPLIELGWSRADCVKYLSSRGLADTPKSSCLGCPFHGNAQWRHIRDTSPGEWADVVAFDAAIRQGNARANAGGNRLLGQAFLHRYRVPLDEAPIDHVSAAERATLQQELGSDDDIALLEEGVPDGCSPWACRGDAEALSRDDFGLAT
>NZ_CP047147.1|WP_159313502.1|6429215_6429824_-|hypothetical-protein
MTFLDLSDVFVGSTDDGHTFVVLNRRVRGADKTLTEAGFHRQAHPGRTLYLLPPGLPEEANERVGTATDGLLAHTHDLVDLSWTTRWDPDRPDSAADLHVQFLSGTVVLTPKSTATRTLLSQHTDLASAADGSFRPQTGLDQRRQLAIVTAIETHAFMHSLKVHIDLDIPTPSEIPAGTRPRTQTATATGVPTPTTVRRRPR

Crispr_ID: NZ_CP047147_42

• CRISPR_ID: NZ_CP047147_42
• CRISPR_location: 7259027-7259118
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP047147_42

Consensus_repeat	Method
GGGAGCATCCCCGCGGGTGCGGGGCCGACAC	CRISPRCasFinder

spacers of NZ_CP047147_42

>42.1|7259058|30|NZ_CP047147|CRISPRCasFinder
GCTGGCTCCCCGGCTCAAACACAGCGACCA

CRISPR arrays and Neighbor proteins around NZ_CP047147_42

CRISPR arrays

The CRISPR arrays of NZ_CP047147_42

>merge|NZ_CP047147|42|7259027-7259118|CRISPRCasFinder
GGGAGCATCCCCGCGGGTGCGGGGCCGACACGCTGGCTCCCCGGCTCAAACACAGCGACCAGGGAGCATCCCCGCGGGTGCGGGGCCGACAC

>NZ_CP047147|42|35|7259027-7259118|CRISPRCasFinder
GGGAGCATCCCCGCGGGTGCGGGGCCGACAC	GCTGGCTCCCCGGCTCAAACACAGCGACCA
GGGAGCATCCCCGCGGGTGCGGGGCCGACAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_159313820.1|7263394_7263724_-|PadR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|367559
NZ_CP047147.1|WP_159314024.1|7261175_7261982_-|hypothetical-protein	unknown	unknown	gnl|CDD|238949
NZ_CP047147.1|WP_159311672.1|7266948_7268055_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|379165
NZ_CP047147.1|WP_159311670.1|7273715_7275950_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|238045
NZ_CP047147.1|WP_159311671.1|7271143_7273495_-|DNA-binding-protein	unknown	unknown	gnl|CDD|367510
NZ_CP047147.1|WP_159313813.1|7252780_7255117_+|beta-glucosidase	unknown	unknown	gnl|CDD|185053
NZ_CP047147.1|WP_159313830.1|7265995_7266865_-|hypothetical-protein	unknown	unknown	gnl|CDD|377670
NZ_CP047147.1|WP_018894638.1|7247854_7248790_+|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|224096
NZ_CP047147.1|WP_159313816.1|7256534_7257377_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|366444
NZ_CP047147.1|WP_159313815.1|7256051_7256306_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_008406812.1|7248804_7249632_+|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl|CDD|223472
NZ_CP047147.1|WP_159313810.1|7246532_7247822_+|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|224567
NZ_CP047147.1|WP_159313829.1|7268051_7270169_-|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl|CDD|366234
NZ_CP047147.1|WP_159313821.1|7264876_7265191_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159313812.1|7250794_7252729_+|cellulase-family-glycosylhydrolase	unknown	unknown	gnl|CDD|226444
NZ_CP047147.1|WP_159313818.1|7260703_7261147_-|NUDIX-domain-containing-protein	unknown	unknown	gnl|CDD|240038
NZ_CP047147.1|WP_159313817.1|7257373_7258312_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|130256
NZ_CP047147.1|WP_159313819.1|7262582_7263398_-|ATP-binding-protein	unknown	unknown	gnl|CDD|99707
NZ_CP047147.1|WP_159313811.1|7249628_7250705_+|substrate-binding-domain-containing-protein	unknown	unknown	gnl|CDD|224525
NZ_CP047147.1|WP_159313814.1|7255716_7255932_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_159313820.1|7263394_7263724_-|PadR-family-transcriptional-regulator	gnl|CDD|367559	pfam03551, PadR, Transcriptional regulator PadR-like family. Members of this family are transcriptional regulators that appear to be related to the pfam01047 family. This family includes PadR, a protein that is involved in negative regulation of phenolic acid metabolism.	2.70052e-08
NZ_CP047147.1|WP_159314024.1|7261175_7261982_-|hypothetical-protein	gnl|CDD|238949	cd01991, Asn_Synthase_B_C, The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B catalyzes the assembly of asparagine from aspartate, Mg(2+)ATP, and glutamine. The three-dimensional architecture of the N-terminal domain of asparagine synthetase B is similar to that observed for glutamine phosphoribosylpyrophosphate amidotransferase while the molecular motif of the C-domain is reminiscent to that observed for GMP synthetase .	1.14577e-16
NZ_CP047147.1|WP_159311672.1|7266948_7268055_-|AAA-family-ATPase	gnl|CDD|379165	pfam13401, AAA_22, AAA domain.	2.83216e-09
NZ_CP047147.1|WP_159311670.1|7273715_7275950_+|helix-turn-helix-domain-containing-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	5.60209e-09
NZ_CP047147.1|WP_159311671.1|7271143_7273495_-|DNA-binding-protein	gnl|CDD|367510	pfam03457, HA, Helicase associated domain. This short domain is found in multiple copies in bacterial helicase proteins. The domain is predicted to contain 3 alpha helices. The function of this domain may be to bind nucleic acid.	2.7663e-11
NZ_CP047147.1|WP_159313813.1|7252780_7255117_+|beta-glucosidase	gnl|CDD|185053	PRK15098, PRK15098, beta-glucosidase BglX.	4.58322e-127
NZ_CP047147.1|WP_018894638.1|7247854_7248790_+|sugar-ABC-transporter-permease	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	3.85342e-54
NZ_CP047147.1|WP_159313816.1|7256534_7257377_-|ABC-transporter-permease	gnl|CDD|366444	pfam01061, ABC2_membrane, ABC-2 type transporter.	1.31283e-16
NZ_CP047147.1|WP_008406812.1|7248804_7249632_+|carbohydrate-ABC-transporter-permease	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	8.73083e-59
NZ_CP047147.1|WP_159313810.1|7246532_7247822_+|extracellular-solute-binding-protein	gnl|CDD|224567	COG1653, UgpB, ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism].	1.60422e-25
NZ_CP047147.1|WP_159313829.1|7268051_7270169_-|DDE-type-integrase/transposase/recombinase	gnl|CDD|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	1.46914e-10
NZ_CP047147.1|WP_159313812.1|7250794_7252729_+|cellulase-family-glycosylhydrolase	gnl|CDD|226444	COG3934, COG3934, Endo-beta-mannanase [Carbohydrate transport and metabolism].	1.25752e-29
NZ_CP047147.1|WP_159313830.1|7265995_7266865_-|hypothetical-protein	gnl|CDD|377670	pfam06527, TniQ, TniQ. This family consists of several bacterial TniQ proteins. TniQ along with TniA and B is involved in the transposition of the mercury-resistance transposon Tn5053 which carries the mer operon. It has been suggested that the tni genes are involved in the dissemination of integrons.	0.00185986
NZ_CP047147.1|WP_159313817.1|7257373_7258312_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|130256	TIGR01188, drrA, daunorubicin resistance ABC transporter ATP-binding subunit. This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other].	1.02305e-111
NZ_CP047147.1|WP_159313819.1|7262582_7263398_-|ATP-binding-protein	gnl|CDD|99707	cd00009, AAA, The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.	1.67947e-06
NZ_CP047147.1|WP_159313811.1|7249628_7250705_+|substrate-binding-domain-containing-protein	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	3.36834e-97
NZ_CP047147.1|WP_159313818.1|7260703_7261147_-|NUDIX-domain-containing-protein	gnl|CDD|240038	cd04682, Nudix_Hydrolase_23, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	5.94373e-19

Protein sequences

>NZ_CP047147.1|WP_159313817.1|7257373_7258312_-|ATP-binding-cassette-domain-containing-protein
MSDRDLAIVVEGLRKKYKDKQALDGLDLTVRAGTVQGVLGPNGAGKTTAVRIMSTLLRADEGRVEVAGIDVRTRADDVRSQIGLLGQNAAVDEELSGRQNLEMFGRLYHLGARRAGARADELLEQFGLTETGAKAVKQYSGGMRRRLDLAASLISRPQVLFLDEPTTGLDPRGRTEVWNAVRSLVGGGTTVLLTTQYLEEADQLADQIAVINRGQVIAEGTADELKTKTGGDRIDVILHDVAQLERAASLLPGAVDKDEDRRMVSASISNRMAALTETVRALQEAGIEAEDIAVRRPTLDEVFMHLTMEEAA
>NZ_CP047147.1|WP_159313816.1|7256534_7257377_-|ABC-transporter-permease
MTATHDVATTAPVSRTHGTGSKLSWAFADSWTMTRRELAHWARQPVQVVVGLVFPVMMLLMFGFLIGGGKGVEGDFRSYLVPGMLTMTMAFGLEATMLSVTQDLGKGVIDRFRSMPMNSGSILVGRSIADMLQSVVGLAVMIGVGAAIGWRWNNGFASFMGAVGLLLLLRFAMLWIGLHLAMVAGKPEMVQAVQILVWPMAFLSNAIATPASMPAWLGGVVEWNPMSATATAVRDLFGNQSAAGDSWAATHAELLAVAWPLLLVAIFFPLAVKRFRDLSR
>NZ_CP047147.1|WP_159313815.1|7256051_7256306_+|hypothetical-protein
MSDLPADLPCLHVLRTWHAMWLARIDKAIATAEQREAETRRGAEVRPPLAGARVRPLDTEQARQALVDVQACSMCRPDTDLGLL
>NZ_CP047147.1|WP_159313814.1|7255716_7255932_-|hypothetical-protein
MEISLATVLALALCGRRVHWVLGARQLPTEAHAWVWTENGAFGLSGRDRPDPRRPWAGALAAPPVPKGRRI
>NZ_CP047147.1|WP_159313813.1|7252780_7255117_+|beta-glucosidase
MADPLYRDPTAPVTARVRDLLARMTLTEKVGQVNQRMYGWHAYERTPSGYRLTEAFRTEVAAFDGMGALYGLQRADPWSGVTAETGIGAADGAHVSDTVQRHVIDNTRLGIPVLMVEEMPHGHQALDGTLLPVNLAVGATWNPELYEEAVAAAAAELRARGGHVALVSALDLVRDPRWGRAEECFGEDPYLAARFTEALVRGAQGAPAERIAPDRAAVVLKHFAGQGATIGGRNSAATELGIRELHEIHLEAALAGVRAGAAGVMAAYNEFDGLPCAASRDLLTGILREEWGFDGVVMADGLALDRLVRLAGNPVTAAATALSAGCDLSLWDDCFPRLAEAVDRGLVEESALDTAVGRVLALKFRLGLFEQPYTGERPRVAAPRELSRRLAQESVTLLAHDGVTLPLPGRARVAVLGPNADSVPQQLGDYTAPQRPGVGLSLLAGLRAAAPAGTEITYARGCDLVGADRSALPEAVALAADSDVAILVLGGSSARAAETHFDANGAAQVTGDPDGMTCGEGVDLADLALPEGQSALLDTITAIGVLVVVVLVQGRPHPLPDLTGRAAAVLSAWYPGPWGGQAVADVLLGTAEPTGRLPVSVPRTAAQLPVFYNAKDHGYRGYVDQPATARHPFGHGLSYTTVEYGAPRLTRPAATLAEFDEAGETGGTPPLVCSVEVRNTGDRPVRETVQLYVRRVLGGTSWPRVRELRGFRHTQLAPGETSEVSFTVDARTLASVSRSGKREVEAGEYAIETGPSSARTQPARLTVHDERGTTFPGP
>NZ_CP047147.1|WP_159313812.1|7250794_7252729_+|cellulase-family-glycosylhydrolase
MRRHSAQLTHDHAVLPWLGANFWSRTGGPLMWRDYDPKTVREELAVLREHGLTMTRSFFYWPDFHPEPSRIDEELCDRFRDFLDAHTEAGMGTVPTFIVGHMSGENWDPVWRGGRDLYEDVWLVGRQAWFVSQMTRRFKDHPAVTGWLITNEMPGYGRIYQENPPSGDVVTAWAQFMCDAVRAAGGTQPVSLGDGAWGIEVTGRDNGFSLRDTAEYVDFVGPHVYRSDTDRPRQHYRAAFECELAAVTGQPVVLEEFGLSTDTVSAANAGIFYRQTLHNSLLGGATGWIAWNNTDYDALWDRSPYDHHPFEMHFGITDSEGRPKEPLRELAGFAEVLERVDFARCRRTDADAALVVPAFLERGYPYSRPADRPLIFTSLHQGYVAARGADLPVALAREADGLAEDAALYLLPSTRQLTTRTRRALERRAREGATVYLSFCSGEHPGTRGPWFDDLDGLFGVELQLSYGVAEPIEDDVLEMTFTEEFGTIKAGETLTFPVAGNEDSRAYLPVVPDGARVVATDAHGRPALLRHDTGQGRTVLATYPLEHMAARTARVNPEQTHRLYAALAEIAGVVRPVTVDSPYVAADTIVHEDGRRFVWLVSQSGKELTVRPSADGTLHSLDDGDPVRDVTLPPYGVRVLEQR
>NZ_CP047147.1|WP_159313811.1|7249628_7250705_+|substrate-binding-domain-containing-protein
MKERLEGRPGRSAPGNGTRPTIKAVAAAAGVSTATVSQAVNDTGRISEATRRRVLAAAAELGWSPSAPATALRRARTRTIALVVRRPTDVLGADPHFSELITGLEGQLAPRGYGLLLHLVPDMAEESALYERLAAEGRIDGAVLTDARADDPRPGLLKGLGLPAVLLGTPDPAAPVPGVGLGQQDAGVREAVTHLLNHGHRRIAYVAGPADLVHSGLRRAAFESALAEAGLRPVAVRHTDFTEEAAVTVTAELLARPDRPTALVFPNDSMAVCGMGAAQRAGLRVPEDVSVVGYDNLPLGRWLHPRLTTVDQQVQRVGAAAALTLLAGCGEEVPAPLLDGRPRLVVRESTGPAPTGRP
>NZ_CP047147.1|WP_008406812.1|7248804_7249632_+|carbohydrate-ABC-transporter-permease
MKFGRSWLPAHLLAWLYAALLLVPLYYLLVSAFKTNDQIFGSPFALPTSLSPHNFTEAFTSADLGAAVVNSVLVTALALALTLGLAIPAAFALARSDGRLGAFVERVFSLGFLVPTFAALFPTFLLAASTGLFHTRAFMVLFLPATAMPLSVVILVQFMRTIPREMEEAARMDGASTFAVLRHVYTPMCMPGIATILLLNFLTFWNEYLYSLVIIGPDPGLRTVQVALPTLKSLTGTDYGILTAGTVLTLVPVWAVYTVLQKRMQQALVSGAVKM
>NZ_CP047147.1|WP_018894638.1|7247854_7248790_+|sugar-ABC-transporter-permease
MTLLSSAPPGAPATRSAPQAPGRTPRRKQGGVILAVPALAWYLLFMVGPLVAIFVIAALHWPGMLQPVSFAGLGNVRTVLADPVFTDALVNTGIQLAVALPVMIVGAYMLGYYVAQRPPGHRFLRYLLFIPGLISTPAKAMVFYAVLSPDGLFNGALDKAGLGSLTDAWLASPSTALACLIVLDVWSGIGFTAVLFAARLGSVPDEVGEAAQLDGAGHWRAMWRIHFPMIRDFVGVVTMLQFLWTLFGSAQNVLLLTQGGPGSSSTTLSFLVYQKAFIAADLGYSQTVGVFLFLAGLAGLLTIRRVFRQNY
>NZ_CP047147.1|WP_159313810.1|7246532_7247822_+|extracellular-solute-binding-protein
MRSPLSRRGFLAAGSGLAAATAFPALAGCSSLASADSDPGTLVVHTQLGTTAPGSPTYRALVKEFHAEHPGLRIKNLVNGDDLPQVYETSRLARKEPDVVMVNLYDKTLAWTELGATLDVKGYLDDWGLRERVLPAALKEWTDDEGRLRAFPYFAANWPVAFNTSLLARAGTGSVPTTGDQLLGAARKLRAKGIAPVTVGGNDWTGQKLLAQIIQTFLTPEEARKVYASGDFGGRRVREGIDYFVELRDAGVFADKAQGLTSDTMTTQYNTEAAAIQSAMSSALAKVPERTAAHSEVGGWPLAPGAAHAKPTIMRSYTLIGFWISPNGAKKISAVEKFLRFMYRPESVSRFITESGRDMALRTDTVSKDFPLVAAAQRLGDQVGQVLLPDLYVPPTATQPLITATSTAFTRGTSAATVRSALESAYRTG
>NZ_CP047147.1|WP_159313818.1|7260703_7261147_-|NUDIX-domain-containing-protein
MDSQTLPDEPSAAEPRGAVAIITNRRGELLLHLRDNIAGIAWPDHWSLLGGGCDPGEAPAAAIVRELDEEAGLAVDDLAELFETKDGAGSGQIITFFSGTWNGDEQALPLAEGIKLQFFPPEHLPVLTIPPFIRHGIHRHLAARPRA
>NZ_CP047147.1|WP_159314024.1|7261175_7261982_-|hypothetical-protein
MHALDYPMGNASTFSEHMAYRAIAERGIQVVAGGMGPDEFLMGYVRHALVLFGPKAVLGAGMESYRPLASKLLHPVGEPLDSAEAIVRLILRGQDPDAHLHQVVADPLARAGGDLARGLTLADLATAWRPLVMTSDKLASAFTLERRSPFQARDLVEFCYRLPVEHKIGDQAAGKRILRDAAKALGLPREVWDSRDKLGFASPVPSWLTGPLEPWATAQISSALDQAPRSLRPLLAGGLKPGGRFDRPRMQSLMAAAWFNDQPVETAA
>NZ_CP047147.1|WP_159313819.1|7262582_7263398_-|ATP-binding-protein
MSVEVIIFMTTAVILPLLLTEFGDWCPWLAKRLAQWTAQRLGDAQAAERYSEEWLAELRHLPGKLSHLLTATSYLLALPRIRWSLRAARLMTPTGPTLDELLPTRVPIYWDPRGANMNWGHQADAAYQLLRAILNDDLQVRNRMHFLVGPVGCGKTVVAHWLHEHFVRDGKKIHYVWAHAWVNRERYIHVSSRMRDRLVQASQEVDLLVVDEADQATVEALEALRLPCPILVLARSHGELGEISRLPANAGTVVNMGPILDSWLQARPNTP
>NZ_CP047147.1|WP_159313820.1|7263394_7263724_-|PadR-family-transcriptional-regulator
MSYPFRVTDATVDVVEALLSGDDELYGLKIAKTIGRPSGSVVPILMRLEACGWVLSEWEQNESARGPRRRFYRLHADRVGEARRLVNERKPASSTVPSGILRPGLGGAR
>NZ_CP047147.1|WP_159313821.1|7264876_7265191_+|hypothetical-protein
MRDLERADGVRPMAQQIQMPPVRRDHLRQPRQIDLLDVGRPAVDPVGAEHPAPMTRADPGVRFQVQPGGLGTPGACGRAQPAAFSRGGHYAPEPEPPGRARPVR
>NZ_CP047147.1|WP_159313830.1|7265995_7266865_-|hypothetical-protein
MPSAAPGVLRVRPLPGEATASYVQRLAGTYQLTLSQLLDGVGITLHSHGTLPAAELHLNHNAARRLAALARFPLPHLKHALPHLALPSDAHDTEAAAHWKRLEAAQPPVRACTLCTRHRSHDTTDTAWAHTAPQRLVCPRDQQAAPDPRLTSTVRTWAVPELVAAHHAHQRLLRRPRALTAWTTARAITTRWYDHQQHLTHRWHTRLARLCATNPHLTTTGSASPTLLARDLVTYPETVALAGALAALPNQPHRDTGKALNVIAHRLGLPRLPLNASDPIRVFLTHTRH
>NZ_CP047147.1|WP_159311672.1|7266948_7268055_-|AAA-family-ATPase
MNASPGTSDASARRSPSTAARRPGAAASTTDDPTDAQQRSVTTWDGFHAFVTAPVAAPPPPGAPPRSLEERLAYHSRFVTVRTPAIDALAKNVRTLMILGRHQAVTARPSLIVTGPAGAGKTTALLQVGRACHLAHTRRHGAAATAGQAPVAYVLVPPAASAKTLAIEFARYLGIPITAGMSQAQITNAVCHTYTAARVQLVLIDEIHRLNPRTTTGAQSADLIKDLTERIGATFVYAGIDVTTTPLFTGVRGAQLAGRASLIDCDPFPARLGDEEPFRDLITAMEGALDLRHHRTGTLPKLAPYLHERTAGRIGSLARLIRQAAITALLDGTERITKTTLDTIRLDHLAEQHYQPRARPRSRSTSTP
>NZ_CP047147.1|WP_159313829.1|7268051_7270169_-|DDE-type-integrase/transposase/recombinase
MVEVGAHITYRGQTWQVAALQGQQVYLVQEDGAEMSLLLGRLFADPGFEVVGGRAPEVVPQWGLFETVPVAAQQRALAWLPHIREVETGWPHPEGGREGQAMRPEYDPERWTLAQRDAAKAKELAALGFARVTRTTVERMRHVYRKQGLWGLVDKRTVPARGRHPTGYADERVVAAVLEALRRQRGRSKGTVKGLQVVVGQILEDTHGRGVVEMPSRSTFYRLVSVLADPADRPGRPARTATAPARASSAPVVLRPGEQVQIDTTRLDIMTVLEDGSLGRPELTIAVDVATRSILAAVLRPHSTKAVDAALLLAEMAVPHPARPTWPSALHLSRAEVPYERMLSLDERLEGAAARPVVVPETIVVDRGKIYLSQGFVAACETLGVSVQPAPPRRPQAKAVVERTFGAINDLFCQHVAGHTGSNPQRRGVATEAETRWTIPQLQDFLDEWITCGWQNRPHDGLRHPVLPKSALTPNQMWAVLITISGYVPVPLSGADYLELLPVRWQPITERGIRLDYRTYNHDILDPHRGQRSPVASKDGKWEVHHNPHDARQIFVRLTDGHLHEVPWIHLDHVHQPFNDALWRDIQTKVEQRGDRDQHEADLADALDQLLRRTRHPAETEQKTRRRRARSGTAAQLPDLPGQRRPLDSETAPAPAPDWNESLDDLISVDTAAETGTSEPNGMGVLPAEAGGYGLWDAEAEAEQW
>NZ_CP047147.1|WP_159311671.1|7271143_7273495_-|DNA-binding-protein
MTDPFTPWAAVGVVRLAPLAGETTLSFVNRLAARYEVTVTGLLSAVAGPGVRGVWGKGCLIGEVFLAPAVRGRLASLCQVPEPHLSRALPSWEEGADEKVSGDQSNVRFASGSMVPAVMLGCRLCTAARTGTPCPARLYSDLRSRICIRHQCWSLDSLALDRATLIEGQMSLAGVPEVIRAHQRLLPLLRRGGSCESAFAVAQAVVSSWWDAHWRDEVLWPARLGRVRSDLPDGEIPVLARDVVTYPETVAVTTVLSDRLWRQRVLEDTRGQMPHTLAEVPRLLTELARCLGRPWLVEQLASSSAGALFAWVRACVRRERGAVPEEDVWAVPVAHRPRGLAAQVRELRLQHVGRAPVGGMPSRAEQAYQVGLAHACSYAARHGHLAVPKYGRHEGFALGPWLANQRTGVAALPIERAQALHRIDPWWNGPWPISWRRTCHRALVHVQKHGLVDATAGFPGTSLALGEWLHEQCSRYDDLHVGQQSLLSDLGIRPAHARSARPRRKSLAQAFAAGLDYARAFAAVHGHLATSKSTQQDGFPLGQWLMSQRSRARMAEQETDRSRALSAIDPWWNPPWPLAWQRAYHHARKQCGSHQPLVPGDGFAGMGASAASWLYAQCALFEELHPRQQDLLQEIGITVEGAQARQTARYRPTGARIDFAVGLAHARDYAGVHGHLALPHPVQHHGFPLGRWLAGKRGEAGAHARRTPAPWPGMQALVALDPWWFPPWAFAWQRDYHRLRLLLAAGLEPSPKLRSWISEQLAQLHTLLPGQQRLLQELRIFPV
>NZ_CP047147.1|WP_159311670.1|7273715_7275950_+|helix-turn-helix-domain-containing-protein
MSELFDAVDALLASRAVLPPPAERKRLRAAHGLTIDEVATALKVRRATVSGWESGKTEPRPPERDAYARLLDGLAKLYPATANTGAAEEDAAVPAMFAAPVAPAPEAQALHTGPARGAAAMTTAHENTQTPAPTAAPATASRPARTAGPPSTSRPPGARKAAPAGGIDPRFENGPLAVLDVDADGKVLAYCTGGLVLDVPAKSLPSLVDWTLKEAKLGQPKLSGPGKDADPLLVLTEAALERYGLPVTLTDEERLAGRIPENHKVIKQLTRADWQLTKRGFGPWARIYRPAKGSDRQCVQLCIPSWNALDTRHWGDAWQLLPADLARVLGVYASRVMTPRGSTAVTGLELMTVLHPPTRASEPDENGKRTSEHNPGSLGKDPVDCAPCEAPDGHPLLKDLPRFHVRGPAEKLFEEAYDWARPMTDAECTLRHLVGIDVNLAFGAGANGLTVGLGEPTHVKNPVFDPKLPGSWLVDLSHVDQSRVKVAKDTWADLDASLLPSPFTPKGNRPEDPAWYATPTVAYAVELGYDVAPIEAYIRYDNGRYLDGWYTRLRNAYLATMADLGVAAGLSPEDFLAAMDGCKGRDPELAIVVSAIKATVKGGLGKLRERPRGEGWRPGEPWRALSRPTWRPDIRAAVISRTRINLHRKIVKHAAFTGQYPIAILSDCVVYAANGPSPLDFLPYRQGKPLPGGFKLGINPGLVKHEGTQSVLWGEEVRERFNAPELNLARYIKDGTVTDVDNGE

Crispr_ID: NZ_CP047147_41

• CRISPR_ID: NZ_CP047147_41
• CRISPR_location: 7258854-7258946
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP047147_41

Consensus_repeat	Method
GGGAGCATCCCCGCGGGTGCGGGGCCGACAC	CRISPRCasFinder

spacers of NZ_CP047147_41

>41.1|7258885|30|NZ_CP047147|CRISPRCasFinder
GCCCGTCATGAAGCCCGTCTACTGCCCCGG

CRISPR arrays and Neighbor proteins around NZ_CP047147_41

CRISPR arrays

The CRISPR arrays of NZ_CP047147_41

>merge|NZ_CP047147|41|7258854-7258946|CRISPRCasFinder
CGGAGCACCCCCACAGGTGCGCGGCCGACCAGCCCGTCATGAAGCCCGTCTACTGCCCCGGCGAAGCATCCCCGCGGGTGCGGGACTGACTCG

>NZ_CP047147|41|34|7258854-7258946|CRISPRCasFinder
CGGAGCACCCCCACAGGTGCGCGGCCGACCA	GCCCGTCATGAAGCCCGTCTACTGCCCCGG
CGAAGCATCCCCGCGGGTGCGGGACTGACTCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047147.1|WP_159313820.1|7263394_7263724_-|PadR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|367559
NZ_CP047147.1|WP_159314024.1|7261175_7261982_-|hypothetical-protein	unknown	unknown	gnl|CDD|238949
NZ_CP047147.1|WP_159311672.1|7266948_7268055_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|379165
NZ_CP047147.1|WP_159311670.1|7273715_7275950_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|238045
NZ_CP047147.1|WP_159311671.1|7271143_7273495_-|DNA-binding-protein	unknown	unknown	gnl|CDD|367510
NZ_CP047147.1|WP_159313813.1|7252780_7255117_+|beta-glucosidase	unknown	unknown	gnl|CDD|185053
NZ_CP047147.1|WP_159313830.1|7265995_7266865_-|hypothetical-protein	unknown	unknown	gnl|CDD|377670
NZ_CP047147.1|WP_018894638.1|7247854_7248790_+|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|224096
NZ_CP047147.1|WP_159313816.1|7256534_7257377_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|366444
NZ_CP047147.1|WP_159313815.1|7256051_7256306_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_008406812.1|7248804_7249632_+|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl|CDD|223472
NZ_CP047147.1|WP_159313810.1|7246532_7247822_+|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|224567
NZ_CP047147.1|WP_159313829.1|7268051_7270169_-|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl|CDD|366234
NZ_CP047147.1|WP_159313821.1|7264876_7265191_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP047147.1|WP_159313812.1|7250794_7252729_+|cellulase-family-glycosylhydrolase	unknown	unknown	gnl|CDD|226444
NZ_CP047147.1|WP_159313818.1|7260703_7261147_-|NUDIX-domain-containing-protein	unknown	unknown	gnl|CDD|240038
NZ_CP047147.1|WP_159313817.1|7257373_7258312_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|130256
NZ_CP047147.1|WP_159313819.1|7262582_7263398_-|ATP-binding-protein	unknown	unknown	gnl|CDD|99707
NZ_CP047147.1|WP_159313811.1|7249628_7250705_+|substrate-binding-domain-containing-protein	unknown	unknown	gnl|CDD|224525
NZ_CP047147.1|WP_159313814.1|7255716_7255932_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP047147.1|WP_159313820.1|7263394_7263724_-|PadR-family-transcriptional-regulator	gnl|CDD|367559	pfam03551, PadR, Transcriptional regulator PadR-like family. Members of this family are transcriptional regulators that appear to be related to the pfam01047 family. This family includes PadR, a protein that is involved in negative regulation of phenolic acid metabolism.	2.70052e-08
NZ_CP047147.1|WP_159314024.1|7261175_7261982_-|hypothetical-protein	gnl|CDD|238949	cd01991, Asn_Synthase_B_C, The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B catalyzes the assembly of asparagine from aspartate, Mg(2+)ATP, and glutamine. The three-dimensional architecture of the N-terminal domain of asparagine synthetase B is similar to that observed for glutamine phosphoribosylpyrophosphate amidotransferase while the molecular motif of the C-domain is reminiscent to that observed for GMP synthetase .	1.14577e-16
NZ_CP047147.1|WP_159311672.1|7266948_7268055_-|AAA-family-ATPase	gnl|CDD|379165	pfam13401, AAA_22, AAA domain.	2.83216e-09
NZ_CP047147.1|WP_159311670.1|7273715_7275950_+|helix-turn-helix-domain-containing-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	5.60209e-09
NZ_CP047147.1|WP_159311671.1|7271143_7273495_-|DNA-binding-protein	gnl|CDD|367510	pfam03457, HA, Helicase associated domain. This short domain is found in multiple copies in bacterial helicase proteins. The domain is predicted to contain 3 alpha helices. The function of this domain may be to bind nucleic acid.	2.7663e-11
NZ_CP047147.1|WP_159313813.1|7252780_7255117_+|beta-glucosidase	gnl|CDD|185053	PRK15098, PRK15098, beta-glucosidase BglX.	4.58322e-127
NZ_CP047147.1|WP_018894638.1|7247854_7248790_+|sugar-ABC-transporter-permease	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	3.85342e-54
NZ_CP047147.1|WP_159313816.1|7256534_7257377_-|ABC-transporter-permease	gnl|CDD|366444	pfam01061, ABC2_membrane, ABC-2 type transporter.	1.31283e-16
NZ_CP047147.1|WP_008406812.1|7248804_7249632_+|carbohydrate-ABC-transporter-permease	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	8.73083e-59
NZ_CP047147.1|WP_159313810.1|7246532_7247822_+|extracellular-solute-binding-protein	gnl|CDD|224567	COG1653, UgpB, ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism].	1.60422e-25
NZ_CP047147.1|WP_159313829.1|7268051_7270169_-|DDE-type-integrase/transposase/recombinase	gnl|CDD|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	1.46914e-10
NZ_CP047147.1|WP_159313812.1|7250794_7252729_+|cellulase-family-glycosylhydrolase	gnl|CDD|226444	COG3934, COG3934, Endo-beta-mannanase [Carbohydrate transport and metabolism].	1.25752e-29
NZ_CP047147.1|WP_159313830.1|7265995_7266865_-|hypothetical-protein	gnl|CDD|377670	pfam06527, TniQ, TniQ. This family consists of several bacterial TniQ proteins. TniQ along with TniA and B is involved in the transposition of the mercury-resistance transposon Tn5053 which carries the mer operon. It has been suggested that the tni genes are involved in the dissemination of integrons.	0.00185986
NZ_CP047147.1|WP_159313817.1|7257373_7258312_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|130256	TIGR01188, drrA, daunorubicin resistance ABC transporter ATP-binding subunit. This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other].	1.02305e-111
NZ_CP047147.1|WP_159313819.1|7262582_7263398_-|ATP-binding-protein	gnl|CDD|99707	cd00009, AAA, The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.	1.67947e-06
NZ_CP047147.1|WP_159313811.1|7249628_7250705_+|substrate-binding-domain-containing-protein	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	3.36834e-97
NZ_CP047147.1|WP_159313818.1|7260703_7261147_-|NUDIX-domain-containing-protein	gnl|CDD|240038	cd04682, Nudix_Hydrolase_23, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	5.94373e-19

Protein sequences

>NZ_CP047147.1|WP_159313817.1|7257373_7258312_-|ATP-binding-cassette-domain-containing-protein
MSDRDLAIVVEGLRKKYKDKQALDGLDLTVRAGTVQGVLGPNGAGKTTAVRIMSTLLRADEGRVEVAGIDVRTRADDVRSQIGLLGQNAAVDEELSGRQNLEMFGRLYHLGARRAGARADELLEQFGLTETGAKAVKQYSGGMRRRLDLAASLISRPQVLFLDEPTTGLDPRGRTEVWNAVRSLVGGGTTVLLTTQYLEEADQLADQIAVINRGQVIAEGTADELKTKTGGDRIDVILHDVAQLERAASLLPGAVDKDEDRRMVSASISNRMAALTETVRALQEAGIEAEDIAVRRPTLDEVFMHLTMEEAA
>NZ_CP047147.1|WP_159313816.1|7256534_7257377_-|ABC-transporter-permease
MTATHDVATTAPVSRTHGTGSKLSWAFADSWTMTRRELAHWARQPVQVVVGLVFPVMMLLMFGFLIGGGKGVEGDFRSYLVPGMLTMTMAFGLEATMLSVTQDLGKGVIDRFRSMPMNSGSILVGRSIADMLQSVVGLAVMIGVGAAIGWRWNNGFASFMGAVGLLLLLRFAMLWIGLHLAMVAGKPEMVQAVQILVWPMAFLSNAIATPASMPAWLGGVVEWNPMSATATAVRDLFGNQSAAGDSWAATHAELLAVAWPLLLVAIFFPLAVKRFRDLSR
>NZ_CP047147.1|WP_159313815.1|7256051_7256306_+|hypothetical-protein
MSDLPADLPCLHVLRTWHAMWLARIDKAIATAEQREAETRRGAEVRPPLAGARVRPLDTEQARQALVDVQACSMCRPDTDLGLL
>NZ_CP047147.1|WP_159313814.1|7255716_7255932_-|hypothetical-protein
MEISLATVLALALCGRRVHWVLGARQLPTEAHAWVWTENGAFGLSGRDRPDPRRPWAGALAAPPVPKGRRI
>NZ_CP047147.1|WP_159313813.1|7252780_7255117_+|beta-glucosidase
MADPLYRDPTAPVTARVRDLLARMTLTEKVGQVNQRMYGWHAYERTPSGYRLTEAFRTEVAAFDGMGALYGLQRADPWSGVTAETGIGAADGAHVSDTVQRHVIDNTRLGIPVLMVEEMPHGHQALDGTLLPVNLAVGATWNPELYEEAVAAAAAELRARGGHVALVSALDLVRDPRWGRAEECFGEDPYLAARFTEALVRGAQGAPAERIAPDRAAVVLKHFAGQGATIGGRNSAATELGIRELHEIHLEAALAGVRAGAAGVMAAYNEFDGLPCAASRDLLTGILREEWGFDGVVMADGLALDRLVRLAGNPVTAAATALSAGCDLSLWDDCFPRLAEAVDRGLVEESALDTAVGRVLALKFRLGLFEQPYTGERPRVAAPRELSRRLAQESVTLLAHDGVTLPLPGRARVAVLGPNADSVPQQLGDYTAPQRPGVGLSLLAGLRAAAPAGTEITYARGCDLVGADRSALPEAVALAADSDVAILVLGGSSARAAETHFDANGAAQVTGDPDGMTCGEGVDLADLALPEGQSALLDTITAIGVLVVVVLVQGRPHPLPDLTGRAAAVLSAWYPGPWGGQAVADVLLGTAEPTGRLPVSVPRTAAQLPVFYNAKDHGYRGYVDQPATARHPFGHGLSYTTVEYGAPRLTRPAATLAEFDEAGETGGTPPLVCSVEVRNTGDRPVRETVQLYVRRVLGGTSWPRVRELRGFRHTQLAPGETSEVSFTVDARTLASVSRSGKREVEAGEYAIETGPSSARTQPARLTVHDERGTTFPGP
>NZ_CP047147.1|WP_159313812.1|7250794_7252729_+|cellulase-family-glycosylhydrolase
MRRHSAQLTHDHAVLPWLGANFWSRTGGPLMWRDYDPKTVREELAVLREHGLTMTRSFFYWPDFHPEPSRIDEELCDRFRDFLDAHTEAGMGTVPTFIVGHMSGENWDPVWRGGRDLYEDVWLVGRQAWFVSQMTRRFKDHPAVTGWLITNEMPGYGRIYQENPPSGDVVTAWAQFMCDAVRAAGGTQPVSLGDGAWGIEVTGRDNGFSLRDTAEYVDFVGPHVYRSDTDRPRQHYRAAFECELAAVTGQPVVLEEFGLSTDTVSAANAGIFYRQTLHNSLLGGATGWIAWNNTDYDALWDRSPYDHHPFEMHFGITDSEGRPKEPLRELAGFAEVLERVDFARCRRTDADAALVVPAFLERGYPYSRPADRPLIFTSLHQGYVAARGADLPVALAREADGLAEDAALYLLPSTRQLTTRTRRALERRAREGATVYLSFCSGEHPGTRGPWFDDLDGLFGVELQLSYGVAEPIEDDVLEMTFTEEFGTIKAGETLTFPVAGNEDSRAYLPVVPDGARVVATDAHGRPALLRHDTGQGRTVLATYPLEHMAARTARVNPEQTHRLYAALAEIAGVVRPVTVDSPYVAADTIVHEDGRRFVWLVSQSGKELTVRPSADGTLHSLDDGDPVRDVTLPPYGVRVLEQR
>NZ_CP047147.1|WP_159313811.1|7249628_7250705_+|substrate-binding-domain-containing-protein
MKERLEGRPGRSAPGNGTRPTIKAVAAAAGVSTATVSQAVNDTGRISEATRRRVLAAAAELGWSPSAPATALRRARTRTIALVVRRPTDVLGADPHFSELITGLEGQLAPRGYGLLLHLVPDMAEESALYERLAAEGRIDGAVLTDARADDPRPGLLKGLGLPAVLLGTPDPAAPVPGVGLGQQDAGVREAVTHLLNHGHRRIAYVAGPADLVHSGLRRAAFESALAEAGLRPVAVRHTDFTEEAAVTVTAELLARPDRPTALVFPNDSMAVCGMGAAQRAGLRVPEDVSVVGYDNLPLGRWLHPRLTTVDQQVQRVGAAAALTLLAGCGEEVPAPLLDGRPRLVVRESTGPAPTGRP
>NZ_CP047147.1|WP_008406812.1|7248804_7249632_+|carbohydrate-ABC-transporter-permease
MKFGRSWLPAHLLAWLYAALLLVPLYYLLVSAFKTNDQIFGSPFALPTSLSPHNFTEAFTSADLGAAVVNSVLVTALALALTLGLAIPAAFALARSDGRLGAFVERVFSLGFLVPTFAALFPTFLLAASTGLFHTRAFMVLFLPATAMPLSVVILVQFMRTIPREMEEAARMDGASTFAVLRHVYTPMCMPGIATILLLNFLTFWNEYLYSLVIIGPDPGLRTVQVALPTLKSLTGTDYGILTAGTVLTLVPVWAVYTVLQKRMQQALVSGAVKM
>NZ_CP047147.1|WP_018894638.1|7247854_7248790_+|sugar-ABC-transporter-permease
MTLLSSAPPGAPATRSAPQAPGRTPRRKQGGVILAVPALAWYLLFMVGPLVAIFVIAALHWPGMLQPVSFAGLGNVRTVLADPVFTDALVNTGIQLAVALPVMIVGAYMLGYYVAQRPPGHRFLRYLLFIPGLISTPAKAMVFYAVLSPDGLFNGALDKAGLGSLTDAWLASPSTALACLIVLDVWSGIGFTAVLFAARLGSVPDEVGEAAQLDGAGHWRAMWRIHFPMIRDFVGVVTMLQFLWTLFGSAQNVLLLTQGGPGSSSTTLSFLVYQKAFIAADLGYSQTVGVFLFLAGLAGLLTIRRVFRQNY
>NZ_CP047147.1|WP_159313810.1|7246532_7247822_+|extracellular-solute-binding-protein
MRSPLSRRGFLAAGSGLAAATAFPALAGCSSLASADSDPGTLVVHTQLGTTAPGSPTYRALVKEFHAEHPGLRIKNLVNGDDLPQVYETSRLARKEPDVVMVNLYDKTLAWTELGATLDVKGYLDDWGLRERVLPAALKEWTDDEGRLRAFPYFAANWPVAFNTSLLARAGTGSVPTTGDQLLGAARKLRAKGIAPVTVGGNDWTGQKLLAQIIQTFLTPEEARKVYASGDFGGRRVREGIDYFVELRDAGVFADKAQGLTSDTMTTQYNTEAAAIQSAMSSALAKVPERTAAHSEVGGWPLAPGAAHAKPTIMRSYTLIGFWISPNGAKKISAVEKFLRFMYRPESVSRFITESGRDMALRTDTVSKDFPLVAAAQRLGDQVGQVLLPDLYVPPTATQPLITATSTAFTRGTSAATVRSALESAYRTG
>NZ_CP047147.1|WP_159313818.1|7260703_7261147_-|NUDIX-domain-containing-protein
MDSQTLPDEPSAAEPRGAVAIITNRRGELLLHLRDNIAGIAWPDHWSLLGGGCDPGEAPAAAIVRELDEEAGLAVDDLAELFETKDGAGSGQIITFFSGTWNGDEQALPLAEGIKLQFFPPEHLPVLTIPPFIRHGIHRHLAARPRA
>NZ_CP047147.1|WP_159314024.1|7261175_7261982_-|hypothetical-protein
MHALDYPMGNASTFSEHMAYRAIAERGIQVVAGGMGPDEFLMGYVRHALVLFGPKAVLGAGMESYRPLASKLLHPVGEPLDSAEAIVRLILRGQDPDAHLHQVVADPLARAGGDLARGLTLADLATAWRPLVMTSDKLASAFTLERRSPFQARDLVEFCYRLPVEHKIGDQAAGKRILRDAAKALGLPREVWDSRDKLGFASPVPSWLTGPLEPWATAQISSALDQAPRSLRPLLAGGLKPGGRFDRPRMQSLMAAAWFNDQPVETAA
>NZ_CP047147.1|WP_159313819.1|7262582_7263398_-|ATP-binding-protein
MSVEVIIFMTTAVILPLLLTEFGDWCPWLAKRLAQWTAQRLGDAQAAERYSEEWLAELRHLPGKLSHLLTATSYLLALPRIRWSLRAARLMTPTGPTLDELLPTRVPIYWDPRGANMNWGHQADAAYQLLRAILNDDLQVRNRMHFLVGPVGCGKTVVAHWLHEHFVRDGKKIHYVWAHAWVNRERYIHVSSRMRDRLVQASQEVDLLVVDEADQATVEALEALRLPCPILVLARSHGELGEISRLPANAGTVVNMGPILDSWLQARPNTP
>NZ_CP047147.1|WP_159313820.1|7263394_7263724_-|PadR-family-transcriptional-regulator
MSYPFRVTDATVDVVEALLSGDDELYGLKIAKTIGRPSGSVVPILMRLEACGWVLSEWEQNESARGPRRRFYRLHADRVGEARRLVNERKPASSTVPSGILRPGLGGAR
>NZ_CP047147.1|WP_159313821.1|7264876_7265191_+|hypothetical-protein
MRDLERADGVRPMAQQIQMPPVRRDHLRQPRQIDLLDVGRPAVDPVGAEHPAPMTRADPGVRFQVQPGGLGTPGACGRAQPAAFSRGGHYAPEPEPPGRARPVR
>NZ_CP047147.1|WP_159313830.1|7265995_7266865_-|hypothetical-protein
MPSAAPGVLRVRPLPGEATASYVQRLAGTYQLTLSQLLDGVGITLHSHGTLPAAELHLNHNAARRLAALARFPLPHLKHALPHLALPSDAHDTEAAAHWKRLEAAQPPVRACTLCTRHRSHDTTDTAWAHTAPQRLVCPRDQQAAPDPRLTSTVRTWAVPELVAAHHAHQRLLRRPRALTAWTTARAITTRWYDHQQHLTHRWHTRLARLCATNPHLTTTGSASPTLLARDLVTYPETVALAGALAALPNQPHRDTGKALNVIAHRLGLPRLPLNASDPIRVFLTHTRH
>NZ_CP047147.1|WP_159311672.1|7266948_7268055_-|AAA-family-ATPase
MNASPGTSDASARRSPSTAARRPGAAASTTDDPTDAQQRSVTTWDGFHAFVTAPVAAPPPPGAPPRSLEERLAYHSRFVTVRTPAIDALAKNVRTLMILGRHQAVTARPSLIVTGPAGAGKTTALLQVGRACHLAHTRRHGAAATAGQAPVAYVLVPPAASAKTLAIEFARYLGIPITAGMSQAQITNAVCHTYTAARVQLVLIDEIHRLNPRTTTGAQSADLIKDLTERIGATFVYAGIDVTTTPLFTGVRGAQLAGRASLIDCDPFPARLGDEEPFRDLITAMEGALDLRHHRTGTLPKLAPYLHERTAGRIGSLARLIRQAAITALLDGTERITKTTLDTIRLDHLAEQHYQPRARPRSRSTSTP
>NZ_CP047147.1|WP_159313829.1|7268051_7270169_-|DDE-type-integrase/transposase/recombinase
MVEVGAHITYRGQTWQVAALQGQQVYLVQEDGAEMSLLLGRLFADPGFEVVGGRAPEVVPQWGLFETVPVAAQQRALAWLPHIREVETGWPHPEGGREGQAMRPEYDPERWTLAQRDAAKAKELAALGFARVTRTTVERMRHVYRKQGLWGLVDKRTVPARGRHPTGYADERVVAAVLEALRRQRGRSKGTVKGLQVVVGQILEDTHGRGVVEMPSRSTFYRLVSVLADPADRPGRPARTATAPARASSAPVVLRPGEQVQIDTTRLDIMTVLEDGSLGRPELTIAVDVATRSILAAVLRPHSTKAVDAALLLAEMAVPHPARPTWPSALHLSRAEVPYERMLSLDERLEGAAARPVVVPETIVVDRGKIYLSQGFVAACETLGVSVQPAPPRRPQAKAVVERTFGAINDLFCQHVAGHTGSNPQRRGVATEAETRWTIPQLQDFLDEWITCGWQNRPHDGLRHPVLPKSALTPNQMWAVLITISGYVPVPLSGADYLELLPVRWQPITERGIRLDYRTYNHDILDPHRGQRSPVASKDGKWEVHHNPHDARQIFVRLTDGHLHEVPWIHLDHVHQPFNDALWRDIQTKVEQRGDRDQHEADLADALDQLLRRTRHPAETEQKTRRRRARSGTAAQLPDLPGQRRPLDSETAPAPAPDWNESLDDLISVDTAAETGTSEPNGMGVLPAEAGGYGLWDAEAEAEQW
>NZ_CP047147.1|WP_159311671.1|7271143_7273495_-|DNA-binding-protein
MTDPFTPWAAVGVVRLAPLAGETTLSFVNRLAARYEVTVTGLLSAVAGPGVRGVWGKGCLIGEVFLAPAVRGRLASLCQVPEPHLSRALPSWEEGADEKVSGDQSNVRFASGSMVPAVMLGCRLCTAARTGTPCPARLYSDLRSRICIRHQCWSLDSLALDRATLIEGQMSLAGVPEVIRAHQRLLPLLRRGGSCESAFAVAQAVVSSWWDAHWRDEVLWPARLGRVRSDLPDGEIPVLARDVVTYPETVAVTTVLSDRLWRQRVLEDTRGQMPHTLAEVPRLLTELARCLGRPWLVEQLASSSAGALFAWVRACVRRERGAVPEEDVWAVPVAHRPRGLAAQVRELRLQHVGRAPVGGMPSRAEQAYQVGLAHACSYAARHGHLAVPKYGRHEGFALGPWLANQRTGVAALPIERAQALHRIDPWWNGPWPISWRRTCHRALVHVQKHGLVDATAGFPGTSLALGEWLHEQCSRYDDLHVGQQSLLSDLGIRPAHARSARPRRKSLAQAFAAGLDYARAFAAVHGHLATSKSTQQDGFPLGQWLMSQRSRARMAEQETDRSRALSAIDPWWNPPWPLAWQRAYHHARKQCGSHQPLVPGDGFAGMGASAASWLYAQCALFEELHPRQQDLLQEIGITVEGAQARQTARYRPTGARIDFAVGLAHARDYAGVHGHLALPHPVQHHGFPLGRWLAGKRGEAGAHARRTPAPWPGMQALVALDPWWFPPWAFAWQRDYHRLRLLLAAGLEPSPKLRSWISEQLAQLHTLLPGQQRLLQELRIFPV
>NZ_CP047147.1|WP_159311670.1|7273715_7275950_+|helix-turn-helix-domain-containing-protein
MSELFDAVDALLASRAVLPPPAERKRLRAAHGLTIDEVATALKVRRATVSGWESGKTEPRPPERDAYARLLDGLAKLYPATANTGAAEEDAAVPAMFAAPVAPAPEAQALHTGPARGAAAMTTAHENTQTPAPTAAPATASRPARTAGPPSTSRPPGARKAAPAGGIDPRFENGPLAVLDVDADGKVLAYCTGGLVLDVPAKSLPSLVDWTLKEAKLGQPKLSGPGKDADPLLVLTEAALERYGLPVTLTDEERLAGRIPENHKVIKQLTRADWQLTKRGFGPWARIYRPAKGSDRQCVQLCIPSWNALDTRHWGDAWQLLPADLARVLGVYASRVMTPRGSTAVTGLELMTVLHPPTRASEPDENGKRTSEHNPGSLGKDPVDCAPCEAPDGHPLLKDLPRFHVRGPAEKLFEEAYDWARPMTDAECTLRHLVGIDVNLAFGAGANGLTVGLGEPTHVKNPVFDPKLPGSWLVDLSHVDQSRVKVAKDTWADLDASLLPSPFTPKGNRPEDPAWYATPTVAYAVELGYDVAPIEAYIRYDNGRYLDGWYTRLRNAYLATMADLGVAAGLSPEDFLAAMDGCKGRDPELAIVVSAIKATVKGGLGKLRERPRGEGWRPGEPWRALSRPTWRPDIRAAVISRTRINLHRKIVKHAAFTGQYPIAILSDCVVYAANGPSPLDFLPYRQGKPLPGGFKLGINPGLVKHEGTQSVLWGEEVRERFNAPELNLARYIKDGTVTDVDNGE

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP047147_6	6.2|1718361|25|NZ_CP047147|CRISPRCasFinder	1718361-1718385	25	NZ_CP047147.1	3474990-3475014	1	0.96
NZ_CP047147_6	6.2|1718361|25|NZ_CP047147|CRISPRCasFinder	1718361-1718385	25	NZ_CP047147.1	4350400-4350424	1	0.96
NZ_CP047147_6	6.2|1718361|25|NZ_CP047147|CRISPRCasFinder	1718361-1718385	25	NZ_CP047147.1	4614147-4614171	1	0.96
NZ_CP047147_6	6.2|1718361|25|NZ_CP047147|CRISPRCasFinder	1718361-1718385	25	NZ_CP047147.1	4699171-4699195	1	0.96
NZ_CP047147_6	6.2|1718361|25|NZ_CP047147|CRISPRCasFinder	1718361-1718385	25	NZ_CP047147.1	4864451-4864475	1	0.96
NZ_CP047147_6	6.2|1718361|25|NZ_CP047147|CRISPRCasFinder	1718361-1718385	25	NZ_CP047147.1	4936026-4936050	1	0.96
NZ_CP047147_9	9.2|2703837|30|NZ_CP047147|PILER-CR	2703837-2703866	30	NZ_CP047147.1	1394953-1394982	1	0.967
NZ_CP047147_5	5.1|1661386|41|NZ_CP047147|CRISPRCasFinder	1661386-1661426	41	NZ_CP047147.1	3721216-3721256	2	0.951
NZ_CP047147_6	6.2|1718361|25|NZ_CP047147|CRISPRCasFinder	1718361-1718385	25	NZ_CP047147.1	1318523-1318547	2	0.92
NZ_CP047147_6	6.2|1718361|25|NZ_CP047147|CRISPRCasFinder	1718361-1718385	25	NZ_CP047147.1	1502375-1502399	2	0.92
NZ_CP047147_6	6.2|1718361|25|NZ_CP047147|CRISPRCasFinder	1718361-1718385	25	NZ_CP047147.1	1553863-1553887	2	0.92
NZ_CP047147_6	6.2|1718361|25|NZ_CP047147|CRISPRCasFinder	1718361-1718385	25	NZ_CP047147.1	1996385-1996409	2	0.92
NZ_CP047147_6	6.2|1718361|25|NZ_CP047147|CRISPRCasFinder	1718361-1718385	25	NZ_CP047147.1	2090467-2090491	2	0.92
NZ_CP047147_6	6.2|1718361|25|NZ_CP047147|CRISPRCasFinder	1718361-1718385	25	NZ_CP047147.1	2231090-2231114	2	0.92
NZ_CP047147_6	6.2|1718361|25|NZ_CP047147|CRISPRCasFinder	1718361-1718385	25	NZ_CP047147.1	2591747-2591771	2	0.92
NZ_CP047147_6	6.2|1718361|25|NZ_CP047147|CRISPRCasFinder	1718361-1718385	25	NZ_CP047147.1	2670906-2670930	2	0.92
NZ_CP047147_6	6.2|1718361|25|NZ_CP047147|CRISPRCasFinder	1718361-1718385	25	NZ_CP047147.1	2867702-2867726	2	0.92
NZ_CP047147_6	6.2|1718361|25|NZ_CP047147|CRISPRCasFinder	1718361-1718385	25	NZ_CP047147.1	3126278-3126302	2	0.92
NZ_CP047147_6	6.2|1718361|25|NZ_CP047147|CRISPRCasFinder	1718361-1718385	25	NZ_CP047147.1	3378212-3378236	2	0.92
NZ_CP047147_6	6.2|1718361|25|NZ_CP047147|CRISPRCasFinder	1718361-1718385	25	NZ_CP047147.1	3475053-3475077	2	0.92
NZ_CP047147_6	6.2|1718361|25|NZ_CP047147|CRISPRCasFinder	1718361-1718385	25	NZ_CP047147.1	4111077-4111101	2	0.92
NZ_CP047147_6	6.2|1718361|25|NZ_CP047147|CRISPRCasFinder	1718361-1718385	25	NZ_CP047147.1	4252162-4252186	2	0.92
NZ_CP047147_6	6.2|1718361|25|NZ_CP047147|CRISPRCasFinder	1718361-1718385	25	NZ_CP047147.1	4252926-4252950	2	0.92
NZ_CP047147_6	6.2|1718361|25|NZ_CP047147|CRISPRCasFinder	1718361-1718385	25	NZ_CP047147.1	4277440-4277464	2	0.92
NZ_CP047147_6	6.2|1718361|25|NZ_CP047147|CRISPRCasFinder	1718361-1718385	25	NZ_CP047147.1	4518266-4518290	2	0.92
NZ_CP047147_6	6.2|1718361|25|NZ_CP047147|CRISPRCasFinder	1718361-1718385	25	NZ_CP047147.1	4518984-4519008	2	0.92
NZ_CP047147_6	6.2|1718361|25|NZ_CP047147|CRISPRCasFinder	1718361-1718385	25	NZ_CP047147.1	4638246-4638270	2	0.92
NZ_CP047147_9	9.2|2703837|30|NZ_CP047147|PILER-CR	2703837-2703866	30	NZ_CP047147.1	1394890-1394919	2	0.933
NZ_CP047147_9	9.4|2703828|38|NZ_CP047147|CRISPRCasFinder	2703828-2703865	38	NZ_CP047147.1	1394945-1394982	2	0.947
NZ_CP047147_13	13.1|3197745|41|NZ_CP047147|CRISPRCasFinder	3197745-3197785	41	NZ_CP047147.1	2441244-2441284	2	0.951
NZ_CP047147_19	19.5|3736605|42|NZ_CP047147|PILER-CR	3736605-3736646	42	NZ_CP047147.1	2121344-2121385	2	0.952
NZ_CP047147_19	19.5|3736605|42|NZ_CP047147|PILER-CR	3736605-3736646	42	NZ_CP047147.1	3198281-3198322	2	0.952
NZ_CP047147_19	19.5|3736605|42|NZ_CP047147|PILER-CR	3736605-3736646	42	NZ_CP047147.1	3721215-3721256	2	0.952
NZ_CP047147_19	19.5|3736605|42|NZ_CP047147|PILER-CR	3736605-3736646	42	NZ_CP047147.1	4277320-4277361	2	0.952
NZ_CP047147_22	22.1|4111160|29|NZ_CP047147|CRISPRCasFinder	4111160-4111188	29	NZ_CP047147.1	2591749-2591777	2	0.931
NZ_CP047147_22	22.1|4111160|29|NZ_CP047147|CRISPRCasFinder	4111160-4111188	29	NZ_CP047147.1	2925185-2925213	2	0.931
NZ_CP047147_22	22.1|4111160|29|NZ_CP047147|CRISPRCasFinder	4111160-4111188	29	NZ_CP047147.1	4111071-4111099	2	0.931

1. spacer 6.2|1718361|25|NZ_CP047147|CRISPRCasFinder matches to position: 3474990-3475014, mismatch: 1, identity: 0.96

atccaagcccggccggcgcttgagg	CRISPR spacer
atcccagcccggccggcgcttgagg	Protospacer
**** ********************

2. spacer 6.2|1718361|25|NZ_CP047147|CRISPRCasFinder matches to position: 4350400-4350424, mismatch: 1, identity: 0.96

atccaagcccggccggcgcttgagg	CRISPR spacer
atcccagcccggccggcgcttgagg	Protospacer
**** ********************

3. spacer 6.2|1718361|25|NZ_CP047147|CRISPRCasFinder matches to position: 4614147-4614171, mismatch: 1, identity: 0.96

atccaagcccggccggcgcttgagg	CRISPR spacer
atcccagcccggccggcgcttgagg	Protospacer
**** ********************

4. spacer 6.2|1718361|25|NZ_CP047147|CRISPRCasFinder matches to position: 4699171-4699195, mismatch: 1, identity: 0.96

atccaagcccggccggcgcttgagg	CRISPR spacer
atcccagcccggccggcgcttgagg	Protospacer
**** ********************

5. spacer 6.2|1718361|25|NZ_CP047147|CRISPRCasFinder matches to position: 4864451-4864475, mismatch: 1, identity: 0.96

atccaagcccggccggcgcttgagg	CRISPR spacer
atcccagcccggccggcgcttgagg	Protospacer
**** ********************

6. spacer 6.2|1718361|25|NZ_CP047147|CRISPRCasFinder matches to position: 4936026-4936050, mismatch: 1, identity: 0.96

atccaagcccggccggcgcttgagg	CRISPR spacer
atcccagcccggccggcgcttgagg	Protospacer
**** ********************

7. spacer 9.2|2703837|30|NZ_CP047147|PILER-CR matches to position: 1394953-1394982, mismatch: 1, identity: 0.967

tcggtgaccggcacggtcagacgtgtccgc	CRISPR spacer
tcggtgaccggcacggtcggacgtgtccgc	Protospacer
******************.***********

8. spacer 5.1|1661386|41|NZ_CP047147|CRISPRCasFinder matches to position: 3721216-3721256, mismatch: 2, identity: 0.951

gttgtgtgccgggctccgtcccgaccgtgccggtcaaagac	CRISPR spacer
gttggttgccgggctccgtcccgaccgtgccggtcaaagac	Protospacer
****  ***********************************

9. spacer 6.2|1718361|25|NZ_CP047147|CRISPRCasFinder matches to position: 1318523-1318547, mismatch: 2, identity: 0.92

atccaagcccggccggcgcttgagg	CRISPR spacer
atcccagcccggccggcggttgagg	Protospacer
**** ************* ******

10. spacer 6.2|1718361|25|NZ_CP047147|CRISPRCasFinder matches to position: 1502375-1502399, mismatch: 2, identity: 0.92

atccaagcccggccggcgcttgagg	CRISPR spacer
atcccagcccggccggcgtttgagg	Protospacer
**** *************.******

11. spacer 6.2|1718361|25|NZ_CP047147|CRISPRCasFinder matches to position: 1553863-1553887, mismatch: 2, identity: 0.92

atccaagcccggccggcgcttgagg	CRISPR spacer
atcccagcccggccggcgattgagg	Protospacer
**** ************* ******

12. spacer 6.2|1718361|25|NZ_CP047147|CRISPRCasFinder matches to position: 1996385-1996409, mismatch: 2, identity: 0.92

atccaagcccggccggcgcttgagg	CRISPR spacer
atctcagcccggccggcgcttgagg	Protospacer
***. ********************

13. spacer 6.2|1718361|25|NZ_CP047147|CRISPRCasFinder matches to position: 2090467-2090491, mismatch: 2, identity: 0.92

atccaagcccggccggcgcttgagg	CRISPR spacer
atctcagcccggccggcgcttgagg	Protospacer
***. ********************

14. spacer 6.2|1718361|25|NZ_CP047147|CRISPRCasFinder matches to position: 2231090-2231114, mismatch: 2, identity: 0.92

atccaagcccggccggcgcttgagg	CRISPR spacer
atctcagcccggccggcgcttgagg	Protospacer
***. ********************

15. spacer 6.2|1718361|25|NZ_CP047147|CRISPRCasFinder matches to position: 2591747-2591771, mismatch: 2, identity: 0.92

atccaagcccggccggcgcttgagg	CRISPR spacer
atctcagcccggccggcgcttgagg	Protospacer
***. ********************

16. spacer 6.2|1718361|25|NZ_CP047147|CRISPRCasFinder matches to position: 2670906-2670930, mismatch: 2, identity: 0.92

atccaagcccggccggcgcttgagg	CRISPR spacer
atctcagcccggccggcgcttgagg	Protospacer
***. ********************

17. spacer 6.2|1718361|25|NZ_CP047147|CRISPRCasFinder matches to position: 2867702-2867726, mismatch: 2, identity: 0.92

atccaagcccggccggcgcttgagg	CRISPR spacer
atcccagcccggccggcgattgagg	Protospacer
**** ************* ******

18. spacer 6.2|1718361|25|NZ_CP047147|CRISPRCasFinder matches to position: 3126278-3126302, mismatch: 2, identity: 0.92

atccaagcccggccggcgcttgagg	CRISPR spacer
atcccagcccggccggcgtttgagg	Protospacer
**** *************.******

19. spacer 6.2|1718361|25|NZ_CP047147|CRISPRCasFinder matches to position: 3378212-3378236, mismatch: 2, identity: 0.92

atccaagcccggccggcgcttgagg	CRISPR spacer
atctcagcccggccggcgcttgagg	Protospacer
***. ********************

20. spacer 6.2|1718361|25|NZ_CP047147|CRISPRCasFinder matches to position: 3475053-3475077, mismatch: 2, identity: 0.92

atccaagcccggccggcgcttgagg	CRISPR spacer
attccagcccggccggcgcttgagg	Protospacer
**.* ********************

21. spacer 6.2|1718361|25|NZ_CP047147|CRISPRCasFinder matches to position: 4111077-4111101, mismatch: 2, identity: 0.92

atccaagcccggccggcgcttgagg	CRISPR spacer
atctcagcccggccggcgcttgagg	Protospacer
***. ********************

22. spacer 6.2|1718361|25|NZ_CP047147|CRISPRCasFinder matches to position: 4252162-4252186, mismatch: 2, identity: 0.92

atccaagcccggccggcgcttgagg	CRISPR spacer
atcccagcccggccggcgtttgagg	Protospacer
**** *************.******

23. spacer 6.2|1718361|25|NZ_CP047147|CRISPRCasFinder matches to position: 4252926-4252950, mismatch: 2, identity: 0.92

atccaagcccggccggcgcttgagg	CRISPR spacer
atcccagcccggccggcgcttcagg	Protospacer
**** **************** ***

24. spacer 6.2|1718361|25|NZ_CP047147|CRISPRCasFinder matches to position: 4277440-4277464, mismatch: 2, identity: 0.92

atccaagcccggccggcgcttgagg	CRISPR spacer
atcccagcccggccggcgtttgagg	Protospacer
**** *************.******

25. spacer 6.2|1718361|25|NZ_CP047147|CRISPRCasFinder matches to position: 4518266-4518290, mismatch: 2, identity: 0.92

atccaagcccggccggcgcttgagg	CRISPR spacer
atcccagcccggccggcgcatgagg	Protospacer
**** ************** *****

26. spacer 6.2|1718361|25|NZ_CP047147|CRISPRCasFinder matches to position: 4518984-4519008, mismatch: 2, identity: 0.92

atccaagcccggccggcgcttgagg	CRISPR spacer
atcccagcccggccggcgtttgagg	Protospacer
**** *************.******

27. spacer 6.2|1718361|25|NZ_CP047147|CRISPRCasFinder matches to position: 4638246-4638270, mismatch: 2, identity: 0.92

atccaagcccggccggcgcttgagg	CRISPR spacer
atctcagcccggccggcgcttgagg	Protospacer
***. ********************

28. spacer 9.2|2703837|30|NZ_CP047147|PILER-CR matches to position: 1394890-1394919, mismatch: 2, identity: 0.933

tcggtgaccggcacggtcagacgtgtccgc	CRISPR spacer
tcggtgacccgcacggtcagaggtgtccgc	Protospacer
********* *********** ********

29. spacer 9.4|2703828|38|NZ_CP047147|CRISPRCasFinder matches to position: 1394945-1394982, mismatch: 2, identity: 0.947

tcggtgaccggcacggtcagacgtgtccgcgccaaaac	CRISPR spacer
tcggtgaccggcacggtcggacgtgtccgcaccaaaac	Protospacer
******************.***********.*******

30. spacer 13.1|3197745|41|NZ_CP047147|CRISPRCasFinder matches to position: 2441244-2441284, mismatch: 2, identity: 0.951

gtgggttgccgggctccgtctcgaccgtgccggtcactgac	CRISPR spacer
gttggtcgccgggctccgtctcgaccgtgccggtcactgac	Protospacer
** ***.**********************************

31. spacer 19.5|3736605|42|NZ_CP047147|PILER-CR matches to position: 2121344-2121385, mismatch: 2, identity: 0.952

gttggttgcggggctccgtctcgaccgtgccggtcaaagact	CRISPR spacer
gttggtggccgggctccgtctcgaccgtgccggtcaaagact	Protospacer
****** ** ********************************

32. spacer 19.5|3736605|42|NZ_CP047147|PILER-CR matches to position: 3198281-3198322, mismatch: 2, identity: 0.952

gttggttgcggggctccgtctcgaccgtgccggtcaaagact	CRISPR spacer
gttggttgcggggctccgtctcgaccgtgccggtcacggact	Protospacer
************************************ .****

33. spacer 19.5|3736605|42|NZ_CP047147|PILER-CR matches to position: 3721215-3721256, mismatch: 2, identity: 0.952

gttggttgcggggctccgtctcgaccgtgccggtcaaagact	CRISPR spacer
gttggttgccgggctccgtcccgaccgtgccggtcaaagact	Protospacer
********* **********.*********************

34. spacer 19.5|3736605|42|NZ_CP047147|PILER-CR matches to position: 4277320-4277361, mismatch: 2, identity: 0.952

gttggttgcggggctccgtctcgaccgtgccggtcaaagact	CRISPR spacer
gtcggttgccgggctccgtctcgaccgtgccggtcaaagact	Protospacer
**.****** ********************************

35. spacer 22.1|4111160|29|NZ_CP047147|CRISPRCasFinder matches to position: 2591749-2591777, mismatch: 2, identity: 0.931

cggtggcctcaagcgccggcccggctcag	CRISPR spacer
cggtggcctcaagcgccggccgggctgag	Protospacer
********************* **** **

36. spacer 22.1|4111160|29|NZ_CP047147|CRISPRCasFinder matches to position: 2925185-2925213, mismatch: 2, identity: 0.931

cggtggcctcaagcgccggcccggctcag	CRISPR spacer
cggtggcctcaagcgccggccgggctgag	Protospacer
********************* **** **

37. spacer 22.1|4111160|29|NZ_CP047147|CRISPRCasFinder matches to position: 4111071-4111099, mismatch: 2, identity: 0.931

cggtggcctcaagcgccggcccggctcag	CRISPR spacer
cggtggcctcaagcgccggccgggctgag	Protospacer
********************* **** **

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP047147_38	38.9|6410493|37|NZ_CP047147|CRISPRCasFinder,CRT	6410493-6410529	37	NC_013667	Streptomyces sp. Y27 plasmid pWTY27, complete sequence	3013-3049	0	1.0
NZ_CP047147_38	38.11|6410641|37|NZ_CP047147|CRISPRCasFinder,CRT	6410641-6410677	37	NC_013667	Streptomyces sp. Y27 plasmid pWTY27, complete sequence	3013-3049	0	1.0
NZ_CP047147_20	20.8|3767377|24|NZ_CP047147|CRT	3767377-3767400	24	NZ_CP018075	Streptomyces venezuelae strain NRRL B-65442 plasmid, complete sequence	133590-133613	1	0.958
NZ_CP047147_21	21.4|3866482|31|NZ_CP047147|CRISPRCasFinder	3866482-3866512	31	NZ_CP009804	Streptomyces sp. FR-008 plasmid pSSFR2, complete sequence	11129-11159	1	0.968
NZ_CP047147_21	21.9|3866482|32|NZ_CP047147|PILER-CR,CRT	3866482-3866513	32	NZ_CP009804	Streptomyces sp. FR-008 plasmid pSSFR2, complete sequence	11129-11160	1	0.969
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NC_016115	Streptomyces pratensis ATCC 33331 plasmid pSFLA02, complete sequence	56489-56524	1	0.972
NZ_CP047147_37	37.19|6408888|36|NZ_CP047147|CRISPRCasFinder,PILER-CR	6408888-6408923	36	NZ_CP010408	Streptomyces vietnamensis strain GIMV4.0001 plasmid pSVL1, complete sequence	226428-226463	1	0.972
NZ_CP047147_38	38.9|6410493|37|NZ_CP047147|CRISPRCasFinder,CRT	6410493-6410529	37	NZ_CP029340	Streptomyces sp. SM17 plasmid pSM17B, complete sequence	398-434	1	0.973
NZ_CP047147_38	38.9|6410493|37|NZ_CP047147|CRISPRCasFinder,CRT	6410493-6410529	37	NZ_CP029340	Streptomyces sp. SM17 plasmid pSM17B, complete sequence	15093-15129	1	0.973
NZ_CP047147_38	38.11|6410641|37|NZ_CP047147|CRISPRCasFinder,CRT	6410641-6410677	37	NZ_CP029340	Streptomyces sp. SM17 plasmid pSM17B, complete sequence	398-434	1	0.973
NZ_CP047147_38	38.11|6410641|37|NZ_CP047147|CRISPRCasFinder,CRT	6410641-6410677	37	NZ_CP029340	Streptomyces sp. SM17 plasmid pSM17B, complete sequence	15093-15129	1	0.973
NZ_CP047147_38	38.15|6410936|36|NZ_CP047147|CRISPRCasFinder,CRT	6410936-6410971	36	ASHF01000034	Streptomyces sp. GBA 94-10 plasmid pGBA1, complete sequence, whole genome shotgun sequence	59162-59197	1	0.972
NZ_CP047147_38	38.16|6411009|36|NZ_CP047147|CRISPRCasFinder,CRT	6411009-6411044	36	NC_019307	Streptomyces sp. W75 plasmid pCQ4, complete sequence	61635-61670	1	0.972
NZ_CP047147_20	20.1|3767002|24|NZ_CP047147|CRT	3767002-3767025	24	NZ_CP039919	Agrobacterium tumefaciens strain CFBP6626 plasmid pAtCFBP6626b, complete sequence	44559-44582	2	0.917
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP015446	Streptomyces sp. S8 plasmid unnamed, complete sequence	12299-12334	2	0.944
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NC_004719	Streptomyces avermitilis MA-4680 = NBRC 14893 plasmid SAP1, complete sequence	37220-37255	2	0.944
NZ_CP047147_37	37.19|6408888|36|NZ_CP047147|CRISPRCasFinder,PILER-CR	6408888-6408923	36	NZ_CP032053	Streptomyces clavuligerus strain F1D-5 plasmid pSCL2, complete sequence	32861-32896	2	0.944
NZ_CP047147_37	37.21|6409035|39|NZ_CP047147|CRISPRCasFinder	6409035-6409073	39	NC_013449	Streptomyces sp. W9 plasmid pCQ3, complete sequence	43296-43334	2	0.949
NZ_CP047147_38	38.25|6410491|39|NZ_CP047147|PILER-CR	6410491-6410529	39	NC_013667	Streptomyces sp. Y27 plasmid pWTY27, complete sequence	3011-3049	2	0.949
NZ_CP047147_38	38.27|6410639|39|NZ_CP047147|PILER-CR	6410639-6410677	39	NC_013667	Streptomyces sp. Y27 plasmid pWTY27, complete sequence	3011-3049	2	0.949
NZ_CP047147_38	38.31|6410934|38|NZ_CP047147|PILER-CR	6410934-6410971	38	ASHF01000034	Streptomyces sp. GBA 94-10 plasmid pGBA1, complete sequence, whole genome shotgun sequence	59162-59199	2	0.947
NZ_CP047147_20	20.1|3767002|24|NZ_CP047147|CRT	3767002-3767025	24	NZ_CP024907	Paraburkholderia caledonica strain PHRS4 plasmid pPHRS4, complete sequence	203765-203788	3	0.875
NZ_CP047147_20	20.2|3767044|24|NZ_CP047147|CRT	3767044-3767067	24	NZ_CP039919	Agrobacterium tumefaciens strain CFBP6626 plasmid pAtCFBP6626b, complete sequence	44559-44582	3	0.875
NZ_CP047147_20	20.8|3767377|24|NZ_CP047147|CRT	3767377-3767400	24	NZ_CP018075	Streptomyces venezuelae strain NRRL B-65442 plasmid, complete sequence	133623-133646	3	0.875
NZ_CP047147_20	20.8|3767377|24|NZ_CP047147|CRT	3767377-3767400	24	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	2666-2689	3	0.875
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP026489	Streptomyces sp. 604F plasmid unnamed, complete sequence	44070-44105	3	0.917
NZ_CP047147_38	38.2|6409976|37|NZ_CP047147|CRISPRCasFinder,CRT	6409976-6410012	37	NZ_CP010408	Streptomyces vietnamensis strain GIMV4.0001 plasmid pSVL1, complete sequence	225748-225784	3	0.919
NZ_CP047147_38	38.25|6410491|39|NZ_CP047147|PILER-CR	6410491-6410529	39	NZ_CP029340	Streptomyces sp. SM17 plasmid pSM17B, complete sequence	398-436	3	0.923
NZ_CP047147_38	38.25|6410491|39|NZ_CP047147|PILER-CR	6410491-6410529	39	NZ_CP029340	Streptomyces sp. SM17 plasmid pSM17B, complete sequence	15093-15131	3	0.923
NZ_CP047147_38	38.27|6410639|39|NZ_CP047147|PILER-CR	6410639-6410677	39	NZ_CP029340	Streptomyces sp. SM17 plasmid pSM17B, complete sequence	398-436	3	0.923
NZ_CP047147_38	38.27|6410639|39|NZ_CP047147|PILER-CR	6410639-6410677	39	NZ_CP029340	Streptomyces sp. SM17 plasmid pSM17B, complete sequence	15093-15131	3	0.923
NZ_CP047147_38	38.32|6411007|38|NZ_CP047147|PILER-CR	6411007-6411044	38	NC_019307	Streptomyces sp. W75 plasmid pCQ4, complete sequence	61635-61672	3	0.921
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	LN997843	Streptomyces reticuli genome assembly TUE45, plasmid : II	204885-204920	4	0.889
NZ_CP047147_37	37.17|6408737|41|NZ_CP047147|CRISPRCasFinder	6408737-6408777	41	NC_013449	Streptomyces sp. W9 plasmid pCQ3, complete sequence	84148-84188	5	0.878
NZ_CP047147_38	38.18|6409974|39|NZ_CP047147|PILER-CR	6409974-6410012	39	NZ_CP010408	Streptomyces vietnamensis strain GIMV4.0001 plasmid pSVL1, complete sequence	225748-225786	5	0.872
NZ_CP047147_7	7.1|2587203|32|NZ_CP047147|CRISPRCasFinder	2587203-2587234	32	NZ_CP007257	Rhodococcus erythropolis R138 plasmid pLRE138, complete sequence	237943-237974	6	0.812
NZ_CP047147_7	7.1|2587203|32|NZ_CP047147|CRISPRCasFinder	2587203-2587234	32	NZ_CP045736	Aeromicrobium sp. MF47 plasmid p001, complete sequence	28686-28717	6	0.812
NZ_CP047147_9	9.2|2703837|30|NZ_CP047147|PILER-CR	2703837-2703866	30	NZ_CP016293	Rhizobium leguminosarum strain Vaf10 plasmid unnamed5, complete sequence	231439-231468	6	0.8
NZ_CP047147_22	22.1|4111160|29|NZ_CP047147|CRISPRCasFinder	4111160-4111188	29	NZ_CP030354	Novosphingobium sp. P6W plasmid pP6W1, complete sequence	680221-680249	6	0.793
NZ_CP047147_22	22.1|4111160|29|NZ_CP047147|CRISPRCasFinder	4111160-4111188	29	NZ_CP013576	Rhizobium phaseoli strain N671 plasmid pRphaN671b, complete sequence	87094-87122	6	0.793
NZ_CP047147_22	22.1|4111160|29|NZ_CP047147|CRISPRCasFinder	4111160-4111188	29	NZ_CP013548	Rhizobium phaseoli strain R611 plasmid pRetR611a, complete sequence	87093-87121	6	0.793
NZ_CP047147_22	22.1|4111160|29|NZ_CP047147|CRISPRCasFinder	4111160-4111188	29	NZ_CP013533	Rhizobium phaseoli strain R650 plasmid pRphaR650a, complete sequence	87093-87121	6	0.793
NZ_CP047147_22	22.1|4111160|29|NZ_CP047147|CRISPRCasFinder	4111160-4111188	29	NZ_CP013543	Rhizobium phaseoli strain R620 plasmid pRphaR620a, complete sequence	90503-90531	6	0.793
NZ_CP047147_22	22.1|4111160|29|NZ_CP047147|CRISPRCasFinder	4111160-4111188	29	NZ_CP013570	Rhizobium phaseoli strain N771 plasmid pRphaN771b, complete sequence	87094-87122	6	0.793
NZ_CP047147_34	34.1|5756194|34|NZ_CP047147|CRISPRCasFinder	5756194-5756227	34	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	942836-942869	6	0.824
NZ_CP047147_34	34.1|5756194|34|NZ_CP047147|CRISPRCasFinder	5756194-5756227	34	NZ_CP029833	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed3, complete sequence	393389-393422	6	0.824
NZ_CP047147_34	34.1|5756194|34|NZ_CP047147|CRISPRCasFinder	5756194-5756227	34	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	870286-870319	6	0.824
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	AP021850	Deinococcus grandis ATCC 43672 plasmid: pDEGR-1 DNA, complete genome	104596-104629	6	0.824
NZ_CP047147_7	7.2|2587264|32|NZ_CP047147|CRISPRCasFinder	2587264-2587295	32	NZ_CP016619	Microvirga ossetica strain V5/3m plasmid unnamed2, complete sequence	359435-359466	7	0.781
NZ_CP047147_9	9.2|2703837|30|NZ_CP047147|PILER-CR	2703837-2703866	30	NZ_CP032322	Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence	719053-719082	7	0.767
NZ_CP047147_9	9.2|2703837|30|NZ_CP047147|PILER-CR	2703837-2703866	30	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	415703-415732	7	0.767
NZ_CP047147_21	21.2|3866360|31|NZ_CP047147|CRISPRCasFinder	3866360-3866390	31	NZ_CP023072	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666a, complete sequence	708467-708497	7	0.774
NZ_CP047147_21	21.2|3866360|31|NZ_CP047147|CRISPRCasFinder	3866360-3866390	31	NZ_CP023065	Sinorhizobium sp. CCBAU 05631 plasmid pSS05631a, complete sequence	706625-706655	7	0.774
NZ_CP047147_21	21.3|3866421|31|NZ_CP047147|CRISPRCasFinder	3866421-3866451	31	NZ_CP054841	Acidovorax sp. 16-35-5 plasmid unnamed1, complete sequence	625081-625111	7	0.774
NZ_CP047147_22	22.1|4111160|29|NZ_CP047147|CRISPRCasFinder	4111160-4111188	29	NZ_CP023072	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666a, complete sequence	251675-251703	7	0.759
NZ_CP047147_22	22.1|4111160|29|NZ_CP047147|CRISPRCasFinder	4111160-4111188	29	NZ_LR134451	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 9, complete sequence	161153-161181	7	0.759
NZ_CP047147_26	26.1|4649246|54|NZ_CP047147|CRISPRCasFinder	4649246-4649299	54	NZ_CP023408	Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence	233324-233377	7	0.87
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP016613	Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence	1245466-1245497	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	1404873-1404904	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP021449	Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence	1267447-1267478	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	CP023013	Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence	1387126-1387157	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP021653	Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence	1482235-1482266	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	1461043-1461074	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	1327326-1327357	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP049790	Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence	680555-680586	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP049794	Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence	1991292-1991323	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP049788	Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence	432092-432123	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP022766	Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence	1461337-1461368	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP039340	Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence	1442835-1442866	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP021763	Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence	1465627-1465658	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP021767	Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence	1482189-1482220	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP015116	Ralstonia solanacearum strain EP1 plasmid unnamed, complete sequence	1640525-1640556	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP016555	Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence	1205748-1205779	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP012688	Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence	1482242-1482273	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP049792	Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence	1766453-1766484	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP052069	Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence	1385447-1385478	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP016915	Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence	1276076-1276107	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP016905	Ralstonia solanacearum strain KACC 10709 plasmid unnamed1	465123-465154	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP025986	Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence	1903669-1903700	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP022769	Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence	1468785-1468816	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	1389529-1389560	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP015851	Ralstonia solanacearum strain YC40-M plasmid, complete sequence	1000797-1000828	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP022773	Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence	1178442-1178473	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP022783	Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence	1393324-1393355	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP022791	Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence	1430440-1430471	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	1326348-1326379	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	1371743-1371774	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	1371734-1371765	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP022795	Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence	1390052-1390083	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP052071	Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence	1568857-1568888	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	1327318-1327349	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	1326672-1326703	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	1327309-1327340	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP022482	Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence	1648587-1648618	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP009763	Ralstonia solanacearum OE1-1 plasmid unnamed, complete sequence	1355540-1355571	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	CP023015	Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence	599562-599593	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP022779	Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence	1480266-1480297	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP052075	Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence	1568824-1568855	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP052085	Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence	1445812-1445843	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP052095	Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence	1476164-1476195	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP052105	Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence	1567618-1567649	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP021765	Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence	1465607-1465638	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP052077	Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence	1379411-1379442	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP052087	Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence	1445812-1445843	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP052097	Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence	1476164-1476195	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	CP047139	Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence	1392478-1392509	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP052115	Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence	1567654-1567685	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP052127	Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence	1445812-1445843	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	CP047137	Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence	1337750-1337781	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	1405018-1405049	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP052079	Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence	1379433-1379464	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP052089	Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence	1445015-1445046	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP052093	Ralstonia solanacearum strain FJAT15340.F50 plasmid Plas1, complete sequence	1476164-1476195	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP052101	Ralstonia solanacearum strain FJAT15304.F1 plasmid Plas1, complete sequence	1476164-1476195	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP052099	Ralstonia solanacearum strain FJAT15304.F50 plasmid Plas1, complete sequence	1476164-1476195	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP052107	Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence	1567654-1567685	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP022781	Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence	573676-573707	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP052117	Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence	1567643-1567674	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP052125	Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence	1379433-1379464	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP022793	Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence	1386384-1386415	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	1404999-1405030	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP022785	Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence	1367037-1367068	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP022787	Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence	1420293-1420324	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP022756	Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence	1459171-1459202	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP052129	Ralstonia solanacearum strain FJAT1303.F1 plasmid Plas1, complete sequence	708996-709027	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP052121	Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence	1567643-1567674	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP052123	Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence	1379433-1379464	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP052131	Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence	1445811-1445842	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	CP011998	Ralstonia solanacearum strain YC45 plasmid, complete sequence	1515361-1515392	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP052073	Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence	1568644-1568675	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP052081	Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence	1379433-1379464	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP052083	Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence	1379433-1379464	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP052109	Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence	1567654-1567685	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP052091	Ralstonia solanacearum strain FJAT15340.F6 plasmid Plas1, complete sequence	1476167-1476198	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP052111	Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence	564696-564727	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP052103	Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence	1567665-1567696	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP052119	Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence	1567466-1567497	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP052113	Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence	564696-564727	7	0.781
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	1404985-1405016	7	0.781
NZ_CP047147_34	34.1|5756194|34|NZ_CP047147|CRISPRCasFinder	5756194-5756227	34	NC_010335	Caulobacter sp. K31 plasmid pCAUL01, complete sequence	232268-232301	7	0.794
NZ_CP047147_37	37.5|6408888|49|NZ_CP047147|CRT	6408888-6408936	49	NZ_CP010408	Streptomyces vietnamensis strain GIMV4.0001 plasmid pSVL1, complete sequence	226428-226476	7	0.857
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP036456	Streptomonospora sp. M2 plasmid phiM2, complete sequence	84851-84884	7	0.794
NZ_CP047147_38	38.14|6410863|36|NZ_CP047147|CRISPRCasFinder,CRT	6410863-6410898	36	LN997845	Streptomyces reticuli genome assembly TUE45, plasmid : IV	8148-8183	7	0.806
NZ_CP047147_7	7.1|2587203|32|NZ_CP047147|CRISPRCasFinder	2587203-2587234	32	NZ_CP016083	Streptomyces sp. SAT1 plasmid unnamed3, complete sequence	765005-765036	8	0.75
NZ_CP047147_7	7.1|2587203|32|NZ_CP047147|CRISPRCasFinder	2587203-2587234	32	NZ_CP015237	Rhodococcus fascians D188 plasmid unnamed2, complete sequence	140989-141020	8	0.75
NZ_CP047147_7	7.1|2587203|32|NZ_CP047147|CRISPRCasFinder	2587203-2587234	32	NZ_CP025986	Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence	1042181-1042212	8	0.75
NZ_CP047147_7	7.1|2587203|32|NZ_CP047147|CRISPRCasFinder	2587203-2587234	32	NZ_CP016452	Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence	1968988-1969019	8	0.75
NZ_CP047147_21	21.4|3866482|31|NZ_CP047147|CRISPRCasFinder	3866482-3866512	31	KY014466	Vibrio vulnificus plasmid pVVS1-per1, complete sequence	3770-3800	8	0.742
NZ_CP047147_21	21.5|3866543|31|NZ_CP047147|CRISPRCasFinder	3866543-3866573	31	NZ_CP021082	Deinococcus ficus strain CC-FR2-10 plasmid pDFI1, complete sequence	66650-66680	8	0.742
NZ_CP047147_21	21.5|3866543|31|NZ_CP047147|CRISPRCasFinder	3866543-3866573	31	MK496050	Pseudomonas sp. strain FFUP_PS_41 plasmid pJBCL41, complete sequence	316997-317027	8	0.742
NZ_CP047147_21	21.7|3866360|32|NZ_CP047147|PILER-CR,CRT	3866360-3866391	32	NZ_CP023072	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666a, complete sequence	708466-708497	8	0.75
NZ_CP047147_21	21.7|3866360|32|NZ_CP047147|PILER-CR,CRT	3866360-3866391	32	NZ_CP023065	Sinorhizobium sp. CCBAU 05631 plasmid pSS05631a, complete sequence	706624-706655	8	0.75
NZ_CP047147_21	21.8|3866421|32|NZ_CP047147|PILER-CR,CRT	3866421-3866452	32	NZ_CP054841	Acidovorax sp. 16-35-5 plasmid unnamed1, complete sequence	625081-625112	8	0.75
NZ_CP047147_34	34.1|5756194|34|NZ_CP047147|CRISPRCasFinder	5756194-5756227	34	CP000662	Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA01, complete sequence	492871-492904	8	0.765
NZ_CP047147_37	37.5|6408888|49|NZ_CP047147|CRT	6408888-6408936	49	NZ_CP032053	Streptomyces clavuligerus strain F1D-5 plasmid pSCL2, complete sequence	32848-32896	8	0.837
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP049788	Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence	1740757-1740792	8	0.778
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	579599-579634	8	0.778
NZ_CP047147_37	37.20|6408961|37|NZ_CP047147|CRISPRCasFinder	6408961-6408997	37	NZ_CP048398	Streptomyces sp. S4.7 plasmid pSSPS4.7a, complete sequence	2428-2464	8	0.784
NZ_CP047147_37	37.20|6408961|37|NZ_CP047147|CRISPRCasFinder	6408961-6408997	37	NZ_CP033585	Streptomyces sp. ADI95-16 plasmid pADI95-16d, complete sequence	2555-2591	8	0.784
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP030074	Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence	523357-523390	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP032322	Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence	953651-953684	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	1384218-1384251	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	1770312-1770345	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP032340	Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence	849903-849936	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	1675170-1675203	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP012915	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence	1282474-1282507	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP016613	Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence	977739-977772	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP021449	Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence	405337-405370	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	CP023013	Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence	1667023-1667056	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP049790	Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence	1692504-1692537	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP049794	Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence	979341-979374	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP049788	Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence	169912-169945	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP022766	Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence	1722437-1722470	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP021763	Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence	1753923-1753956	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP015116	Ralstonia solanacearum strain EP1 plasmid unnamed, complete sequence	1898162-1898195	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP016555	Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence	1374764-1374797	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP049792	Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence	760817-760850	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP052069	Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence	1653172-1653205	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP016915	Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence	265668-265701	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP016905	Ralstonia solanacearum strain KACC 10709 plasmid unnamed1	640600-640633	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP025986	Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence	2108992-2109025	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP022769	Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence	1731933-1731966	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP015851	Ralstonia solanacearum strain YC40-M plasmid, complete sequence	743134-743167	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP022773	Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence	1439557-1439590	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP022783	Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence	1674232-1674265	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP022791	Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence	1691056-1691089	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP022795	Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence	1669051-1669084	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP052071	Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence	1737873-1737906	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP022482	Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence	1379767-1379800	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP009763	Ralstonia solanacearum OE1-1 plasmid unnamed, complete sequence	1611976-1612009	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	CP023015	Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence	1668519-1668552	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP022779	Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence	1743413-1743446	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP052075	Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence	1737840-1737873	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP052085	Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence	1647272-1647305	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP052095	Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence	1722854-1722887	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP052105	Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence	1736634-1736667	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP052077	Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence	1633751-1633784	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP052087	Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence	1647584-1647617	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP052097	Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence	1722854-1722887	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP052115	Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence	1736670-1736703	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP052127	Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence	1647272-1647305	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP052079	Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence	1634397-1634430	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP052089	Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence	1646475-1646508	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP052093	Ralstonia solanacearum strain FJAT15340.F50 plasmid Plas1, complete sequence	1722854-1722887	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP052101	Ralstonia solanacearum strain FJAT15304.F1 plasmid Plas1, complete sequence	1722854-1722887	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP052099	Ralstonia solanacearum strain FJAT15304.F50 plasmid Plas1, complete sequence	1722854-1722887	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP052107	Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence	1736670-1736703	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP022781	Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence	309353-309386	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP052117	Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence	1736659-1736692	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP052125	Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence	1633773-1633806	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP022793	Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence	1647499-1647532	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP022785	Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence	1628145-1628178	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP022787	Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence	1689189-1689222	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP022756	Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence	1721170-1721203	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP052129	Ralstonia solanacearum strain FJAT1303.F1 plasmid Plas1, complete sequence	1720169-1720202	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP052121	Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence	1736659-1736692	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP052123	Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence	1633773-1633806	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP052131	Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence	1647583-1647616	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	CP011998	Ralstonia solanacearum strain YC45 plasmid, complete sequence	1733816-1733849	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP052073	Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence	1737660-1737693	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP052081	Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence	1633773-1633806	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP052083	Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence	1633773-1633806	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP052109	Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence	1736670-1736703	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP052091	Ralstonia solanacearum strain FJAT15340.F6 plasmid Plas1, complete sequence	1722857-1722890	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP052111	Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence	277207-277240	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP052103	Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence	1736681-1736714	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP052119	Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence	1736482-1736515	8	0.765
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP052113	Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence	277207-277240	8	0.765
NZ_CP047147_38	38.14|6410863|36|NZ_CP047147|CRISPRCasFinder,CRT	6410863-6410898	36	NZ_CP030863	Streptomyces globosus strain LZH-48 plasmid unnamed1, complete sequence	80018-80053	8	0.778
NZ_CP047147_7	7.1|2587203|32|NZ_CP047147|CRISPRCasFinder	2587203-2587234	32	NZ_CP020556	Streptomyces sp. Sge12 plasmid pSGE, complete sequence	103587-103618	9	0.719
NZ_CP047147_7	7.1|2587203|32|NZ_CP047147|CRISPRCasFinder	2587203-2587234	32	NZ_CP011869	Pseudonocardia sp. HH130629-09 plasmid pLS1-1, complete sequence	241575-241606	9	0.719
NZ_CP047147_21	21.5|3866543|31|NZ_CP047147|CRISPRCasFinder	3866543-3866573	31	NC_013930	Thioalkalivibrio sp. K90mix plasmid pTK9001, complete sequence	152638-152668	9	0.71
NZ_CP047147_21	21.10|3866543|32|NZ_CP047147|PILER-CR,CRT	3866543-3866574	32	NZ_CP021082	Deinococcus ficus strain CC-FR2-10 plasmid pDFI1, complete sequence	66650-66681	9	0.719
NZ_CP047147_21	21.10|3866543|32|NZ_CP047147|PILER-CR,CRT	3866543-3866574	32	MK496050	Pseudomonas sp. strain FFUP_PS_41 plasmid pJBCL41, complete sequence	316997-317028	9	0.719
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	CP006880	Rhizobium gallicum bv. gallicum R602 plasmid pRgalR602c, complete sequence	2286109-2286140	9	0.719
NZ_CP047147_34	34.1|5756194|34|NZ_CP047147|CRISPRCasFinder	5756194-5756227	34	NZ_CP034351	Streptomyces sp. W1SF4 plasmid p1, complete sequence	61049-61082	9	0.735
NZ_CP047147_34	34.1|5756194|34|NZ_CP047147|CRISPRCasFinder	5756194-5756227	34	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	799816-799849	9	0.735
NZ_CP047147_34	34.1|5756194|34|NZ_CP047147|CRISPRCasFinder	5756194-5756227	34	NC_012811	Methylorubrum extorquens AM1 megaplasmid, complete sequence	573647-573680	9	0.735
NZ_CP047147_34	34.1|5756194|34|NZ_CP047147|CRISPRCasFinder	5756194-5756227	34	NZ_LR134451	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 9, complete sequence	37139-37172	9	0.735
NZ_CP047147_37	37.7|6409035|52|NZ_CP047147|CRT	6409035-6409086	52	NC_013449	Streptomyces sp. W9 plasmid pCQ3, complete sequence	43296-43347	9	0.827
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP021449	Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence	140907-140942	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP049790	Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence	211632-211667	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP049794	Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence	440012-440047	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP022766	Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence	194382-194417	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP021763	Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence	253412-253447	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP016555	Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence	1921038-1921073	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP049792	Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence	221488-221523	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP052069	Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence	194114-194149	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP016915	Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence	806447-806482	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP022769	Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence	195712-195747	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP022773	Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence	201463-201498	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP052071	Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence	207271-207306	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP022779	Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence	195729-195764	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP052075	Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence	207271-207306	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP052085	Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence	212144-212179	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP052095	Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence	190842-190877	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP052105	Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence	207271-207306	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP021765	Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence	253480-253515	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP052087	Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence	212144-212179	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP052097	Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence	190842-190877	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP052115	Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence	207271-207306	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP052127	Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence	212144-212179	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP052089	Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence	212144-212179	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP052093	Ralstonia solanacearum strain FJAT15340.F50 plasmid Plas1, complete sequence	190842-190877	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP052101	Ralstonia solanacearum strain FJAT15304.F1 plasmid Plas1, complete sequence	190842-190877	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP052099	Ralstonia solanacearum strain FJAT15304.F50 plasmid Plas1, complete sequence	190842-190877	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP052107	Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence	207271-207306	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP022781	Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence	200662-200697	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP052117	Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence	207271-207306	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP022793	Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence	201446-201481	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP022785	Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence	201449-201484	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP022787	Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence	196836-196871	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP022756	Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence	197400-197435	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP052129	Ralstonia solanacearum strain FJAT1303.F1 plasmid Plas1, complete sequence	190531-190566	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP052121	Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence	207271-207306	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP052131	Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence	212144-212179	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	CP011998	Ralstonia solanacearum strain YC45 plasmid, complete sequence	213992-214027	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP052073	Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence	207271-207306	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP052109	Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence	207271-207306	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP052091	Ralstonia solanacearum strain FJAT15340.F6 plasmid Plas1, complete sequence	190842-190877	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP052103	Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence	207271-207306	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP052119	Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence	207271-207306	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP016613	Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence	435910-435945	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP016905	Ralstonia solanacearum strain KACC 10709 plasmid unnamed1	1130048-1130083	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP025986	Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence	120892-120927	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP015851	Ralstonia solanacearum strain YC40-M plasmid, complete sequence	194398-194433	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP022791	Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence	31881-31916	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP022482	Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence	901702-901737	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP052111	Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence	1885430-1885465	9	0.75
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP052113	Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence	1885430-1885465	9	0.75
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP053984	Achromobacter pestifer strain FDAARGOS_790 plasmid unnamed, complete sequence	54970-55003	9	0.735
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NC_011879	Pseudarthrobacter chlorophenolicus A6 plasmid pACHL01, complete sequence	5402-5435	9	0.735
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP040820	Paraoceanicella profunda strain D4M1 plasmid pD4M1B, complete sequence	170547-170580	9	0.735
NZ_CP047147_37	37.25|6409470|36|NZ_CP047147|CRISPRCasFinder	6409470-6409505	36	NZ_CP015867	Streptomyces parvulus strain 2297 plasmid pSPA1, complete sequence	579521-579556	9	0.75
NZ_CP047147_38	38.15|6410936|36|NZ_CP047147|CRISPRCasFinder,CRT	6410936-6410971	36	NZ_CP015597	Mycobacterium sp. YC-RL4 plasmid pMYC1, complete sequence	29551-29586	9	0.75
NZ_CP047147_38	38.30|6410861|38|NZ_CP047147|PILER-CR	6410861-6410898	38	LN997845	Streptomyces reticuli genome assembly TUE45, plasmid : IV	8148-8185	9	0.763
NZ_CP047147_7	7.1|2587203|32|NZ_CP047147|CRISPRCasFinder	2587203-2587234	32	NZ_CP024583	Roseomonas sp. FDAARGOS_362 plasmid unnamed2, complete sequence	249902-249933	10	0.688
NZ_CP047147_7	7.1|2587203|32|NZ_CP047147|CRISPRCasFinder	2587203-2587234	32	NC_023283	Streptomyces sp. FR1 plasmid pFRL3, complete sequence	125653-125684	10	0.688
NZ_CP047147_7	7.1|2587203|32|NZ_CP047147|CRISPRCasFinder	2587203-2587234	32	NC_023284	Streptomyces sp. F2 plasmid pFRL4, complete sequence	162281-162312	10	0.688
NZ_CP047147_7	7.2|2587264|32|NZ_CP047147|CRISPRCasFinder	2587264-2587295	32	NZ_AP022607	Mycobacterium branderi strain JCM 12687 plasmid pJCM12687	525019-525050	10	0.688
NZ_CP047147_21	21.10|3866543|32|NZ_CP047147|PILER-CR,CRT	3866543-3866574	32	NC_013930	Thioalkalivibrio sp. K90mix plasmid pTK9001, complete sequence	152637-152668	10	0.688
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	MG298964	Streptomyces phage Alsaber, complete genome	9907-9938	10	0.688
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	MT711979	Streptomyces phage Endor2, complete genome	9741-9772	10	0.688
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	KT186229	Streptomyces phage Verse, complete genome	10007-10038	10	0.688
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	KT186228	Streptomyces phage Amela, complete genome	10013-10044	10	0.688
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NC_041856	Streptomyces phage phiCAM, complete genome	11673-11704	10	0.688
NZ_CP047147_34	34.1|5756194|34|NZ_CP047147|CRISPRCasFinder	5756194-5756227	34	NZ_CP025805	Sulfitobacter sp. SK012 plasmid unnamed1, complete sequence	6300-6333	10	0.706
NZ_CP047147_34	34.1|5756194|34|NZ_CP047147|CRISPRCasFinder	5756194-5756227	34	NZ_CP025806	Sulfitobacter sp. SK012 plasmid unnamed3, complete sequence	101359-101392	10	0.706
NZ_CP047147_34	34.1|5756194|34|NZ_CP047147|CRISPRCasFinder	5756194-5756227	34	NC_020894	Streptomyces hygroscopicus subsp. jinggangensis TL01 plasmid pSHJGH1, complete sequence	34794-34827	10	0.706
NZ_CP047147_34	34.1|5756194|34|NZ_CP047147|CRISPRCasFinder	5756194-5756227	34	NC_017766	Streptomyces hygroscopicus subsp. jinggangensis 5008 plasmid pSHJG1, complete sequence	34794-34827	10	0.706
NZ_CP047147_34	34.1|5756194|34|NZ_CP047147|CRISPRCasFinder	5756194-5756227	34	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	731149-731182	10	0.706
NZ_CP047147_34	34.1|5756194|34|NZ_CP047147|CRISPRCasFinder	5756194-5756227	34	NZ_CP039965	Pseudorhodobacter sp. S12M18 plasmid unnamed1, complete sequence	1474205-1474238	10	0.706
NZ_CP047147_34	34.1|5756194|34|NZ_CP047147|CRISPRCasFinder	5756194-5756227	34	KX522649	Mycobacterium phage Bircsak, complete genome	50306-50339	10	0.706
NZ_CP047147_34	34.1|5756194|34|NZ_CP047147|CRISPRCasFinder	5756194-5756227	34	KX522943	Mycobacterium phage Gompeii16, complete genome	50307-50340	10	0.706
NZ_CP047147_37	37.3|6408740|51|NZ_CP047147|CRT	6408740-6408790	51	NC_013449	Streptomyces sp. W9 plasmid pCQ3, complete sequence	84151-84201	10	0.804
NZ_CP047147_37	37.16|6408664|36|NZ_CP047147|CRISPRCasFinder	6408664-6408699	36	NZ_CP022482	Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence	862147-862182	10	0.722
NZ_CP047147_37	37.18|6408815|36|NZ_CP047147|CRISPRCasFinder,PILER-CR	6408815-6408850	36	NZ_CP039905	Agrobacterium tumefaciens strain CFBP6623 plasmid pAtCFBP6623a, complete sequence	250068-250103	10	0.722
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP026091	Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence	758755-758788	10	0.706
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	758799-758832	10	0.706
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	414525-414558	10	0.706
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NC_017575	Ralstonia solanacearum Po82 megaplasmid, complete sequence	758603-758636	10	0.706
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP051295	Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence	1415258-1415291	10	0.706
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	1604009-1604042	10	0.706
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	1751697-1751730	10	0.706
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	1678485-1678518	10	0.706
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	1522223-1522256	10	0.706
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP039340	Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence	1191329-1191362	10	0.706
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP012940	Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence	1429702-1429735	10	0.706
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	1521245-1521278	10	0.706
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	1590724-1590757	10	0.706
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	1590725-1590758	10	0.706
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	1522215-1522248	10	0.706
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	1521573-1521606	10	0.706
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	1522205-1522238	10	0.706
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP026308	Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence	758581-758614	10	0.706
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP021765	Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence	1753936-1753969	10	0.706
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	CP047139	Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence	532324-532357	10	0.706
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	CP047137	Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence	508488-508521	10	0.706
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	1604178-1604211	10	0.706
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	1604161-1604194	10	0.706
NZ_CP047147_37	37.22|6409111|34|NZ_CP047147|CRISPRCasFinder	6409111-6409144	34	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	1604140-1604173	10	0.706
NZ_CP047147_39	39.1|6417946|35|NZ_CP047147|CRISPRCasFinder	6417946-6417980	35	NZ_CP024314	Rhizobium sp. NXC24 plasmid pRspNXC24c, complete sequence	1107996-1108030	10	0.714
NZ_CP047147_40	40.3|6418296|49|NZ_CP047147|CRISPRCasFinder	6418296-6418344	49	NC_023285	Streptomyces sp. F8 plasmid pFRL5, complete sequence	195438-195486	10	0.796
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_LR594660	Variovorax sp. PBL-H6 plasmid 2	242031-242062	11	0.656
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_LR594667	Variovorax sp. SRS16 plasmid 2	558341-558372	11	0.656
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	NZ_LR594672	Variovorax sp. PBL-E5 plasmid 2	558474-558505	11	0.656
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	MF766045	Streptomyces phage Daudau, complete genome	9759-9790	11	0.656
NZ_CP047147_33	33.1|5746389|32|NZ_CP047147|CRISPRCasFinder	5746389-5746420	32	MT701598	Streptomyces phage Sitrop, complete genome	7401-7432	11	0.656
NZ_CP047147_37	37.2|6408664|52|NZ_CP047147|CRT	6408664-6408715	52	NZ_CP015446	Streptomyces sp. S8 plasmid unnamed, complete sequence	12283-12334	11	0.788
NZ_CP047147_37	37.2|6408664|52|NZ_CP047147|CRT	6408664-6408715	52	NC_004719	Streptomyces avermitilis MA-4680 = NBRC 14893 plasmid SAP1, complete sequence	37204-37255	12	0.769
NZ_CP047147_21	21.1|3866299|31|NZ_CP047147|CRISPRCasFinder	3866299-3866329	31	NZ_CP006989	Rhizobium sp. IE4771 plasmid pRetIE4771c, complete sequence	461198-461228	14	0.548
NZ_CP047147_21	21.1|3866299|31|NZ_CP047147|CRISPRCasFinder	3866299-3866329	31	NZ_CP021126	Rhizobium sp. Kim5 plasmid pRetKim5b, complete sequence	473541-473571	14	0.548
NZ_CP047147_21	21.1|3866299|31|NZ_CP047147|CRISPRCasFinder	3866299-3866329	31	CP007642	Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803a, complete sequence	436267-436297	14	0.548
NZ_CP047147_21	21.6|3866299|32|NZ_CP047147|PILER-CR,CRT	3866299-3866330	32	NZ_CP006989	Rhizobium sp. IE4771 plasmid pRetIE4771c, complete sequence	461197-461228	14	0.562
NZ_CP047147_21	21.6|3866299|32|NZ_CP047147|PILER-CR,CRT	3866299-3866330	32	NZ_CP021126	Rhizobium sp. Kim5 plasmid pRetKim5b, complete sequence	473540-473571	14	0.562
NZ_CP047147_21	21.6|3866299|32|NZ_CP047147|PILER-CR,CRT	3866299-3866330	32	CP007642	Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803a, complete sequence	436266-436297	14	0.562

1. spacer 38.9|6410493|37|NZ_CP047147|CRISPRCasFinder,CRT matches to NC_013667 (Streptomyces sp. Y27 plasmid pWTY27, complete sequence) position: , mismatch: 0, identity: 1.0

tcgtggaccaggcccgcgcgacccactcggggtcacc	CRISPR spacer
tcgtggaccaggcccgcgcgacccactcggggtcacc	Protospacer
*************************************

2. spacer 38.11|6410641|37|NZ_CP047147|CRISPRCasFinder,CRT matches to NC_013667 (Streptomyces sp. Y27 plasmid pWTY27, complete sequence) position: , mismatch: 0, identity: 1.0

tcgtggaccaggcccgcgcgacccactcggggtcacc	CRISPR spacer
tcgtggaccaggcccgcgcgacccactcggggtcacc	Protospacer
*************************************

3. spacer 20.8|3767377|24|NZ_CP047147|CRT matches to NZ_CP018075 (Streptomyces venezuelae strain NRRL B-65442 plasmid, complete sequence) position: , mismatch: 1, identity: 0.958

cgtgacgaccgcccctcgggcggc	CRISPR spacer
cgcgacgaccgcccctcgggcggc	Protospacer
**.*********************

4. spacer 21.4|3866482|31|NZ_CP047147|CRISPRCasFinder matches to NZ_CP009804 (Streptomyces sp. FR-008 plasmid pSSFR2, complete sequence) position: , mismatch: 1, identity: 0.968

ctggcattctcggcctgcgccaaagaattct	CRISPR spacer
ctggcattctcggcctgcgccaaggaattct	Protospacer
***********************.*******

5. spacer 21.9|3866482|32|NZ_CP047147|PILER-CR,CRT matches to NZ_CP009804 (Streptomyces sp. FR-008 plasmid pSSFR2, complete sequence) position: , mismatch: 1, identity: 0.969

ctggcattctcggcctgcgccaaagaattctg	CRISPR spacer
ctggcattctcggcctgcgccaaggaattctg	Protospacer
***********************.********

6. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NC_016115 (Streptomyces pratensis ATCC 33331 plasmid pSFLA02, complete sequence) position: , mismatch: 1, identity: 0.972

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
gctcaccgtgtgcccggagtcgtcggcctgggcgac	Protospacer
*********************.**************

7. spacer 37.19|6408888|36|NZ_CP047147|CRISPRCasFinder,PILER-CR matches to NZ_CP010408 (Streptomyces vietnamensis strain GIMV4.0001 plasmid pSVL1, complete sequence) position: , mismatch: 1, identity: 0.972

cctgaccggtgcgacgttcgccggcgccaactacat	CRISPR spacer
cctggccggtgcgacgttcgccggcgccaactacat	Protospacer
****.*******************************

8. spacer 38.9|6410493|37|NZ_CP047147|CRISPRCasFinder,CRT matches to NZ_CP029340 (Streptomyces sp. SM17 plasmid pSM17B, complete sequence) position: , mismatch: 1, identity: 0.973

tcgtggaccaggcccgcgcgacccactcggggtcacc	CRISPR spacer
tcgtggaccaggcccgcgcgacccactcggggtcgcc	Protospacer
**********************************.**

9. spacer 38.9|6410493|37|NZ_CP047147|CRISPRCasFinder,CRT matches to NZ_CP029340 (Streptomyces sp. SM17 plasmid pSM17B, complete sequence) position: , mismatch: 1, identity: 0.973

tcgtggaccaggcccgcgcgacccactcggggtcacc	CRISPR spacer
tcgtggaccaggcccgcgcgacccactcggggtcgcc	Protospacer
**********************************.**

10. spacer 38.11|6410641|37|NZ_CP047147|CRISPRCasFinder,CRT matches to NZ_CP029340 (Streptomyces sp. SM17 plasmid pSM17B, complete sequence) position: , mismatch: 1, identity: 0.973

tcgtggaccaggcccgcgcgacccactcggggtcacc	CRISPR spacer
tcgtggaccaggcccgcgcgacccactcggggtcgcc	Protospacer
**********************************.**

11. spacer 38.11|6410641|37|NZ_CP047147|CRISPRCasFinder,CRT matches to NZ_CP029340 (Streptomyces sp. SM17 plasmid pSM17B, complete sequence) position: , mismatch: 1, identity: 0.973

tcgtggaccaggcccgcgcgacccactcggggtcacc	CRISPR spacer
tcgtggaccaggcccgcgcgacccactcggggtcgcc	Protospacer
**********************************.**

12. spacer 38.15|6410936|36|NZ_CP047147|CRISPRCasFinder,CRT matches to ASHF01000034 (Streptomyces sp. GBA 94-10 plasmid pGBA1, complete sequence, whole genome shotgun sequence) position: , mismatch: 1, identity: 0.972

cggtgcgcaggtacgcggcggccggctcgtcccacg	CRISPR spacer
cggtccgcaggtacgcggcggccggctcgtcccacg	Protospacer
**** *******************************

13. spacer 38.16|6411009|36|NZ_CP047147|CRISPRCasFinder,CRT matches to NC_019307 (Streptomyces sp. W75 plasmid pCQ4, complete sequence) position: , mismatch: 1, identity: 0.972

aaccctgggcccgcgctggacgtcaccgccatcgtg	CRISPR spacer
aaccctgggcccgcgctggacgtcgccgccatcgtg	Protospacer
************************.***********

14. spacer 20.1|3767002|24|NZ_CP047147|CRT matches to NZ_CP039919 (Agrobacterium tumefaciens strain CFBP6626 plasmid pAtCFBP6626b, complete sequence) position: , mismatch: 2, identity: 0.917

cgtgagggcggtttccgtcgggac	CRISPR spacer
cccgagggcggtttccgtcgggac	Protospacer
* .*********************

15. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP015446 (Streptomyces sp. S8 plasmid unnamed, complete sequence) position: , mismatch: 2, identity: 0.944

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
gctcaccgtttgcccggagtcgtcggcctgggcgac	Protospacer
********* ***********.**************

16. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NC_004719 (Streptomyces avermitilis MA-4680 = NBRC 14893 plasmid SAP1, complete sequence) position: , mismatch: 2, identity: 0.944

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
gctcaccgtgtgcccggagtcggcggcctgggcgac	Protospacer
*********************. *************

17. spacer 37.19|6408888|36|NZ_CP047147|CRISPRCasFinder,PILER-CR matches to NZ_CP032053 (Streptomyces clavuligerus strain F1D-5 plasmid pSCL2, complete sequence) position: , mismatch: 2, identity: 0.944

cctgaccggtgcgacgttcgccggcgccaactacat	CRISPR spacer
cctggccggtgcgacgttcgccggagccaactacat	Protospacer
****.******************* ***********

18. spacer 37.21|6409035|39|NZ_CP047147|CRISPRCasFinder matches to NC_013449 (Streptomyces sp. W9 plasmid pCQ3, complete sequence) position: , mismatch: 2, identity: 0.949

ccggggccacggcgacctcgccgcgcagctcgcctcgca	CRISPR spacer
ccggggccacggcgacctcgccgcgcagctagccgcgca	Protospacer
****************************** *** ****

19. spacer 38.25|6410491|39|NZ_CP047147|PILER-CR matches to NC_013667 (Streptomyces sp. Y27 plasmid pWTY27, complete sequence) position: , mismatch: 2, identity: 0.949

actcgtggaccaggcccgcgcgacccactcggggtcacc	CRISPR spacer
cttcgtggaccaggcccgcgcgacccactcggggtcacc	Protospacer
 .*************************************

20. spacer 38.27|6410639|39|NZ_CP047147|PILER-CR matches to NC_013667 (Streptomyces sp. Y27 plasmid pWTY27, complete sequence) position: , mismatch: 2, identity: 0.949

actcgtggaccaggcccgcgcgacccactcggggtcacc	CRISPR spacer
cttcgtggaccaggcccgcgcgacccactcggggtcacc	Protospacer
 .*************************************

21. spacer 38.31|6410934|38|NZ_CP047147|PILER-CR matches to ASHF01000034 (Streptomyces sp. GBA 94-10 plasmid pGBA1, complete sequence, whole genome shotgun sequence) position: , mismatch: 2, identity: 0.947

accggtgcgcaggtacgcggcggccggctcgtcccacg	CRISPR spacer
gccggtccgcaggtacgcggcggccggctcgtcccacg	Protospacer
.***** *******************************

22. spacer 20.1|3767002|24|NZ_CP047147|CRT matches to NZ_CP024907 (Paraburkholderia caledonica strain PHRS4 plasmid pPHRS4, complete sequence) position: , mismatch: 3, identity: 0.875

cgtgagggcggtttccgtcgggac	CRISPR spacer
ctggaggtcggtttccgtcgggac	Protospacer
*  **** ****************

23. spacer 20.2|3767044|24|NZ_CP047147|CRT matches to NZ_CP039919 (Agrobacterium tumefaciens strain CFBP6626 plasmid pAtCFBP6626b, complete sequence) position: , mismatch: 3, identity: 0.875

cgtgagggcggtttccgtcgcgac	CRISPR spacer
cccgagggcggtttccgtcgggac	Protospacer
* .***************** ***

24. spacer 20.8|3767377|24|NZ_CP047147|CRT matches to NZ_CP018075 (Streptomyces venezuelae strain NRRL B-65442 plasmid, complete sequence) position: , mismatch: 3, identity: 0.875

cgtgacgaccgcccctcgggcggc	CRISPR spacer
cgtgacgaccgcccgtccggcggt	Protospacer
************** ** *****.

25. spacer 20.8|3767377|24|NZ_CP047147|CRT matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.875

cgtgacgaccgcccctcgggcggc	CRISPR spacer
tctgacgaccgcgcctcgggcggc	Protospacer
. ********** ***********

26. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP026489 (Streptomyces sp. 604F plasmid unnamed, complete sequence) position: , mismatch: 3, identity: 0.917

gctcaccgtgtgcccggagtcatcggcctgggcgac-	CRISPR spacer
gctcaccgtgtgcccggagtcgccggcct-ggcgacg	Protospacer
*********************..****** ****** 

27. spacer 38.2|6409976|37|NZ_CP047147|CRISPRCasFinder,CRT matches to NZ_CP010408 (Streptomyces vietnamensis strain GIMV4.0001 plasmid pSVL1, complete sequence) position: , mismatch: 3, identity: 0.919

tctacgcggcgtgcgcgtaggagcccttgtcggtgta	CRISPR spacer
cctacgcggcgggcgcgtaggagcccttgtcgttgta	Protospacer
.********** ******************** ****

28. spacer 38.25|6410491|39|NZ_CP047147|PILER-CR matches to NZ_CP029340 (Streptomyces sp. SM17 plasmid pSM17B, complete sequence) position: , mismatch: 3, identity: 0.923

actcgtggaccaggcccgcgcgacccactcggggtcacc	CRISPR spacer
cttcgtggaccaggcccgcgcgacccactcggggtcgcc	Protospacer
 .**********************************.**

29. spacer 38.25|6410491|39|NZ_CP047147|PILER-CR matches to NZ_CP029340 (Streptomyces sp. SM17 plasmid pSM17B, complete sequence) position: , mismatch: 3, identity: 0.923

actcgtggaccaggcccgcgcgacccactcggggtcacc	CRISPR spacer
cttcgtggaccaggcccgcgcgacccactcggggtcgcc	Protospacer
 .**********************************.**

30. spacer 38.27|6410639|39|NZ_CP047147|PILER-CR matches to NZ_CP029340 (Streptomyces sp. SM17 plasmid pSM17B, complete sequence) position: , mismatch: 3, identity: 0.923

actcgtggaccaggcccgcgcgacccactcggggtcacc	CRISPR spacer
cttcgtggaccaggcccgcgcgacccactcggggtcgcc	Protospacer
 .**********************************.**

31. spacer 38.27|6410639|39|NZ_CP047147|PILER-CR matches to NZ_CP029340 (Streptomyces sp. SM17 plasmid pSM17B, complete sequence) position: , mismatch: 3, identity: 0.923

actcgtggaccaggcccgcgcgacccactcggggtcacc	CRISPR spacer
cttcgtggaccaggcccgcgcgacccactcggggtcgcc	Protospacer
 .**********************************.**

32. spacer 38.32|6411007|38|NZ_CP047147|PILER-CR matches to NC_019307 (Streptomyces sp. W75 plasmid pCQ4, complete sequence) position: , mismatch: 3, identity: 0.921

acaaccctgggcccgcgctggacgtcaccgccatcgtg	CRISPR spacer
cgaaccctgggcccgcgctggacgtcgccgccatcgtg	Protospacer
  ************************.***********

33. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to LN997843 (Streptomyces reticuli genome assembly TUE45, plasmid : II) position: , mismatch: 4, identity: 0.889

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
gctcaccgtgcgcccggagtcgtcggcctgggcgga	Protospacer
**********.**********.************. 

34. spacer 37.17|6408737|41|NZ_CP047147|CRISPRCasFinder matches to NC_013449 (Streptomyces sp. W9 plasmid pCQ3, complete sequence) position: , mismatch: 5, identity: 0.878

caccgtcacgccgaccaggttccccggatcgccgccgtgtt	CRISPR spacer
tgctgtcacgccgaccaggttccacggattgccgccgtgtt	Protospacer
..*.******************* *****.***********

35. spacer 38.18|6409974|39|NZ_CP047147|PILER-CR matches to NZ_CP010408 (Streptomyces vietnamensis strain GIMV4.0001 plasmid pSVL1, complete sequence) position: , mismatch: 5, identity: 0.872

actctacgcggcgtgcgcgtaggagcccttgtcggtgta	CRISPR spacer
ctcctacgcggcgggcgcgtaggagcccttgtcgttgta	Protospacer
 ..********** ******************** ****

36. spacer 7.1|2587203|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP007257 (Rhodococcus erythropolis R138 plasmid pLRE138, complete sequence) position: , mismatch: 6, identity: 0.812

tacctcgtcctcgacgagctgtggcgcgtcct	CRISPR spacer
tacctcgtcctcgacgagccgtggccggcgat	Protospacer
*******************.*****  *.  *

37. spacer 7.1|2587203|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP045736 (Aeromicrobium sp. MF47 plasmid p001, complete sequence) position: , mismatch: 6, identity: 0.812

tacctcgtcctcgacgagctgtggcgcgtcct	CRISPR spacer
ttcgtcgtcctggacgagctgtggcgcgcgat	Protospacer
* * ******* ****************.  *

38. spacer 9.2|2703837|30|NZ_CP047147|PILER-CR matches to NZ_CP016293 (Rhizobium leguminosarum strain Vaf10 plasmid unnamed5, complete sequence) position: , mismatch: 6, identity: 0.8

tcggtgaccggcacggtcagacgtgtccgc	CRISPR spacer
tcggtgaccggcagtgtcagacgtgtattg	Protospacer
*************  *********** .  

39. spacer 22.1|4111160|29|NZ_CP047147|CRISPRCasFinder matches to NZ_CP030354 (Novosphingobium sp. P6W plasmid pP6W1, complete sequence) position: , mismatch: 6, identity: 0.793

cggtggcctcaagcgccggcccggctcag	CRISPR spacer
acgtggccccaagcgccagcccggcgctg	Protospacer
  ******.********.******* * *

40. spacer 22.1|4111160|29|NZ_CP047147|CRISPRCasFinder matches to NZ_CP013576 (Rhizobium phaseoli strain N671 plasmid pRphaN671b, complete sequence) position: , mismatch: 6, identity: 0.793

cggtggcctcaagcgccggcccggctcag	CRISPR spacer
tggtgacctcaagcgccagcccggtgcgg	Protospacer
.****.***********.******. *.*

41. spacer 22.1|4111160|29|NZ_CP047147|CRISPRCasFinder matches to NZ_CP013548 (Rhizobium phaseoli strain R611 plasmid pRetR611a, complete sequence) position: , mismatch: 6, identity: 0.793

cggtggcctcaagcgccggcccggctcag	CRISPR spacer
tggtgacctcaagcgccagcccggtgcgg	Protospacer
.****.***********.******. *.*

42. spacer 22.1|4111160|29|NZ_CP047147|CRISPRCasFinder matches to NZ_CP013533 (Rhizobium phaseoli strain R650 plasmid pRphaR650a, complete sequence) position: , mismatch: 6, identity: 0.793

cggtggcctcaagcgccggcccggctcag	CRISPR spacer
tggtgacctcaagcgccagcccggtgcgg	Protospacer
.****.***********.******. *.*

43. spacer 22.1|4111160|29|NZ_CP047147|CRISPRCasFinder matches to NZ_CP013543 (Rhizobium phaseoli strain R620 plasmid pRphaR620a, complete sequence) position: , mismatch: 6, identity: 0.793

cggtggcctcaagcgccggcccggctcag	CRISPR spacer
tggtgacctcaagcgccagcccggtgcgg	Protospacer
.****.***********.******. *.*

44. spacer 22.1|4111160|29|NZ_CP047147|CRISPRCasFinder matches to NZ_CP013570 (Rhizobium phaseoli strain N771 plasmid pRphaN771b, complete sequence) position: , mismatch: 6, identity: 0.793

cggtggcctcaagcgccggcccggctcag	CRISPR spacer
tggtgacctcaagcgccagcccggtgcgg	Protospacer
.****.***********.******. *.*

45. spacer 34.1|5756194|34|NZ_CP047147|CRISPRCasFinder matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 6, identity: 0.824

---ggatcgatcccgccgccccgcgccccgccgacgc	CRISPR spacer
accggctcg---ccgccgccccgcgcccggccgtcgc	Protospacer
   ** ***   **************** **** ***

46. spacer 34.1|5756194|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP029833 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed3, complete sequence) position: , mismatch: 6, identity: 0.824

ggatcgatcccgccgccccgcgccccgccgacgc-	CRISPR spacer
ggctcgatctcgccgccccgcg-cccgctggagcc	Protospacer
** ******.************ *****.*. ** 

47. spacer 34.1|5756194|34|NZ_CP047147|CRISPRCasFinder matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 6, identity: 0.824

---ggatcgatcccgccgccccgcgccccgccgacgc	CRISPR spacer
accggctcg---ccgccgccccgcgcccggccgtcgc	Protospacer
   ** ***   **************** **** ***

48. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to AP021850 (Deinococcus grandis ATCC 43672 plasmid: pDEGR-1 DNA, complete genome) position: , mismatch: 6, identity: 0.824

gccgtc-gcccagctggccgcccacgcggccgggg	CRISPR spacer
-ctgtcggcccggctggccgcccacgcgaccgcgt	Protospacer
 *.*** ****.****************.*** * 

49. spacer 7.2|2587264|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP016619 (Microvirga ossetica strain V5/3m plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.781

gaggccgctccggtcgtcacgaacatcatcga	CRISPR spacer
gttgccaagccggtcgtcacgaacgacatcga	Protospacer
*  ***.  ***************. ******

50. spacer 9.2|2703837|30|NZ_CP047147|PILER-CR matches to NZ_CP032322 (Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.767

tcggtgaccggcacggtcagacgtgtccgc	CRISPR spacer
tcggtgaccagcacggtcaggcgcgggccg	Protospacer
*********.**********.**.*  *  

51. spacer 9.2|2703837|30|NZ_CP047147|PILER-CR matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 7, identity: 0.767

tcggtgaccggcacggtcagacgtgtccgc	CRISPR spacer
tcggtgaccagcacggtcaggcgcgggccg	Protospacer
*********.**********.**.*  *  

52. spacer 21.2|3866360|31|NZ_CP047147|CRISPRCasFinder matches to NZ_CP023072 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666a, complete sequence) position: , mismatch: 7, identity: 0.774

gcgttcggagcggaccctctgccgaagtaca	CRISPR spacer
gcgttcatagcggaccctctgccacatgacg	Protospacer
******. ***************. *  **.

53. spacer 21.2|3866360|31|NZ_CP047147|CRISPRCasFinder matches to NZ_CP023065 (Sinorhizobium sp. CCBAU 05631 plasmid pSS05631a, complete sequence) position: , mismatch: 7, identity: 0.774

gcgttcggagcggaccctctgccgaagtaca	CRISPR spacer
gcgttcatagcggaccctctgccacatgacg	Protospacer
******. ***************. *  **.

54. spacer 21.3|3866421|31|NZ_CP047147|CRISPRCasFinder matches to NZ_CP054841 (Acidovorax sp. 16-35-5 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.774

acgatgtcgcgggtacgggtcgcgtgcatcg	CRISPR spacer
gcgatgtcgcgcgtacggatcgcgtcctgca	Protospacer
.********** ******.****** *  *.

55. spacer 22.1|4111160|29|NZ_CP047147|CRISPRCasFinder matches to NZ_CP023072 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666a, complete sequence) position: , mismatch: 7, identity: 0.759

cggtggcctcaagcgccggcccggctcag	CRISPR spacer
tggtggcctcaagcgcctgctcggcgact	Protospacer
.**************** **.****    

56. spacer 22.1|4111160|29|NZ_CP047147|CRISPRCasFinder matches to NZ_LR134451 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 9, complete sequence) position: , mismatch: 7, identity: 0.759

cggtggcctcaagcgccggcccggctcag	CRISPR spacer
caacggcctcaagcgctggcccggcaacg	Protospacer
*...************.********   *

57. spacer 26.1|4649246|54|NZ_CP047147|CRISPRCasFinder matches to NZ_CP023408 (Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.87

cgccggggcgcggctgcgccggcagggcgtggagcgcgtccgcatcgtggagac	CRISPR spacer
cgccggggcgcggctgcgccggcagggcgtggaacgcgtccgcctgatcgacaa	Protospacer
*********************************.********* * .* ** * 

58. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP016613 (Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

59. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

60. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP021449 (Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

61. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to CP023013 (Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

62. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP021653 (Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

63. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

64. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

65. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP049790 (Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

66. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP049794 (Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

67. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP049788 (Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

68. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022766 (Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

69. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP039340 (Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

70. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP021763 (Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

71. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP021767 (Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

72. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP015116 (Ralstonia solanacearum strain EP1 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

73. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP016555 (Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

74. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP012688 (Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

75. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP049792 (Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

76. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052069 (Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

77. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP016915 (Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

78. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP016905 (Ralstonia solanacearum strain KACC 10709 plasmid unnamed1) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

79. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP025986 (Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

80. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022769 (Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

81. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

82. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP015851 (Ralstonia solanacearum strain YC40-M plasmid, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

83. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022773 (Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

84. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022783 (Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

85. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022791 (Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

86. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

87. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

88. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

89. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022795 (Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

90. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052071 (Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

91. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

92. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

93. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

94. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022482 (Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

95. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP009763 (Ralstonia solanacearum OE1-1 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

96. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to CP023015 (Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

97. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022779 (Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

98. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052075 (Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

99. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052085 (Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

100. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052095 (Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

101. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052105 (Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

102. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP021765 (Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

103. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052077 (Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

104. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052087 (Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

105. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052097 (Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

106. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to CP047139 (Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

107. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052115 (Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

108. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052127 (Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

109. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to CP047137 (Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

110. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

111. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052079 (Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

112. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052089 (Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

113. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052093 (Ralstonia solanacearum strain FJAT15340.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

114. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052101 (Ralstonia solanacearum strain FJAT15304.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

115. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052099 (Ralstonia solanacearum strain FJAT15304.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

116. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052107 (Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

117. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022781 (Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

118. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052117 (Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

119. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052125 (Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

120. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022793 (Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

121. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

122. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022785 (Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

123. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022787 (Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

124. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022756 (Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

125. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052129 (Ralstonia solanacearum strain FJAT1303.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

126. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052121 (Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

127. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052123 (Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

128. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052131 (Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

129. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to CP011998 (Ralstonia solanacearum strain YC45 plasmid, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

130. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052073 (Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

131. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052081 (Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

132. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052083 (Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

133. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052109 (Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

134. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052091 (Ralstonia solanacearum strain FJAT15340.F6 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

135. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052111 (Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

136. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052103 (Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

137. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052119 (Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

138. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052113 (Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

139. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
tgcacgagcggcacgaaggtcgacgcgaacat	Protospacer
* * .***** ******** ********** .

140. spacer 34.1|5756194|34|NZ_CP047147|CRISPRCasFinder matches to NC_010335 (Caulobacter sp. K31 plasmid pCAUL01, complete sequence) position: , mismatch: 7, identity: 0.794

ggatcgatcccgccgccccgcgccccgccgacgc--	CRISPR spacer
ggatcgatccggccg--ccgcgcgccgccagcacct	Protospacer
********** ****  ****** *****..*.*  

141. spacer 37.5|6408888|49|NZ_CP047147|CRT matches to NZ_CP010408 (Streptomyces vietnamensis strain GIMV4.0001 plasmid pSVL1, complete sequence) position: , mismatch: 7, identity: 0.857

cctgaccggtgcgacgttcgccggcgccaactacatgttgcgatcctcg--	CRISPR spacer
cctggccggtgcgacgttcgccggcgccaactacatgaaccg--cctgggc	Protospacer
****.********************************   **  *** *  

142. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP036456 (Streptomonospora sp. M2 plasmid phiM2, complete sequence) position: , mismatch: 7, identity: 0.794

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gaggccgccccgcaggccgcccacgcggccttgg	Protospacer
*  *.***** ** ****************  **

143. spacer 38.14|6410863|36|NZ_CP047147|CRISPRCasFinder,CRT matches to LN997845 (Streptomyces reticuli genome assembly TUE45, plasmid : IV) position: , mismatch: 7, identity: 0.806

gtccggttcgtcggcggccgcgagctgcgcggcggc	CRISPR spacer
gacgggcccgtcggcggccgcgggctgcggggcgga	Protospacer
* * **..**************.****** ***** 

144. spacer 7.1|2587203|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP016083 (Streptomyces sp. SAT1 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.75

tacctcgtcctcgacgagctgtggcgcgtcct	CRISPR spacer
gacctcgtccccggcgagctgtggatcggcgg	Protospacer
 *********.**.**********  ** *  

145. spacer 7.1|2587203|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP015237 (Rhodococcus fascians D188 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.75

tacctcgtcctcgacgagctgtggcgcgtcct	CRISPR spacer
ggctacgacctcgacgagctgtgccgcgacat	Protospacer
 .*. ** *************** **** * *

146. spacer 7.1|2587203|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP025986 (Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence) position: , mismatch: 8, identity: 0.75

tacctcgtcctcgacgagctgtggcgcgtcct	CRISPR spacer
ccgcccgacctggacgagctgtggcgcgactt	Protospacer
.  *.** *** **************** *.*

147. spacer 7.1|2587203|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP016452 (Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence) position: , mismatch: 8, identity: 0.75

tacctcgtcctcgacgagctgtggcgcgtcct-	CRISPR spacer
cggctcgtcctcggcgagctgcggcg-gccatg	Protospacer
.. **********.*******.**** *.* * 

148. spacer 21.4|3866482|31|NZ_CP047147|CRISPRCasFinder matches to KY014466 (Vibrio vulnificus plasmid pVVS1-per1, complete sequence) position: , mismatch: 8, identity: 0.742

ctggcattctcggcctgcgccaaagaattct-----	CRISPR spacer
gtggctttctcggcctgcgccaa-----tccgggtg	Protospacer
 **** *****************     **.     

149. spacer 21.5|3866543|31|NZ_CP047147|CRISPRCasFinder matches to NZ_CP021082 (Deinococcus ficus strain CC-FR2-10 plasmid pDFI1, complete sequence) position: , mismatch: 8, identity: 0.742

cttgaaccccctcccgcaaatccggtccgct	CRISPR spacer
cgccgacccccacccgcaattccggtccggg	Protospacer
* . .****** ******* *********  

150. spacer 21.5|3866543|31|NZ_CP047147|CRISPRCasFinder matches to MK496050 (Pseudomonas sp. strain FFUP_PS_41 plasmid pJBCL41, complete sequence) position: , mismatch: 8, identity: 0.742

cttgaaccccctcccgcaaatccggtccgct	CRISPR spacer
ccgaaaccccctccctcaaatctggtctgaa	Protospacer
*. .*********** ******.****.*  

151. spacer 21.7|3866360|32|NZ_CP047147|PILER-CR,CRT matches to NZ_CP023072 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666a, complete sequence) position: , mismatch: 8, identity: 0.75

gcgttcggagcggaccctctgccgaagtacac	CRISPR spacer
gcgttcatagcggaccctctgccacatgacga	Protospacer
******. ***************. *  **. 

152. spacer 21.7|3866360|32|NZ_CP047147|PILER-CR,CRT matches to NZ_CP023065 (Sinorhizobium sp. CCBAU 05631 plasmid pSS05631a, complete sequence) position: , mismatch: 8, identity: 0.75

gcgttcggagcggaccctctgccgaagtacac	CRISPR spacer
gcgttcatagcggaccctctgccacatgacga	Protospacer
******. ***************. *  **. 

153. spacer 21.8|3866421|32|NZ_CP047147|PILER-CR,CRT matches to NZ_CP054841 (Acidovorax sp. 16-35-5 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

acgatgtcgcgggtacgggtcgcgtgcatcgc	CRISPR spacer
gcgatgtcgcgcgtacggatcgcgtcctgcat	Protospacer
.********** ******.****** *  *..

154. spacer 34.1|5756194|34|NZ_CP047147|CRISPRCasFinder matches to CP000662 (Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA01, complete sequence) position: , mismatch: 8, identity: 0.765

ggatcgatcccgccgccccgcgccccg-ccgacgc	CRISPR spacer
caccggatcccgccgcccgccgccccgcccgacg-	Protospacer
 . . *************  ******* ****** 

155. spacer 37.5|6408888|49|NZ_CP047147|CRT matches to NZ_CP032053 (Streptomyces clavuligerus strain F1D-5 plasmid pSCL2, complete sequence) position: , mismatch: 8, identity: 0.837

cctgaccggtgcgacgttcgccggcgccaactacatgttgcgatcctcg--	CRISPR spacer
cctggccggtgcgacgttcgccggagccaactacatgaaccg--cctgggc	Protospacer
****.******************* ************   **  *** *  

156. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP049788 (Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.778

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
acacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.* *..* .****** ******** ***********

157. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 8, identity: 0.778

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
acacgccccatgccccgagtcatccgcctgggcgac	Protospacer
.* *.** ..***** ******** ***********

158. spacer 37.20|6408961|37|NZ_CP047147|CRISPRCasFinder matches to NZ_CP048398 (Streptomyces sp. S4.7 plasmid pSSPS4.7a, complete sequence) position: , mismatch: 8, identity: 0.784

ccaagatttactgctccgaccgctgccggaaggcggc	CRISPR spacer
cgcgtgtgtactgctcggaccgctgccggaaggccgc	Protospacer
*  . .* ******** ***************** **

159. spacer 37.20|6408961|37|NZ_CP047147|CRISPRCasFinder matches to NZ_CP033585 (Streptomyces sp. ADI95-16 plasmid pADI95-16d, complete sequence) position: , mismatch: 8, identity: 0.784

ccaagatttactgctccgaccgctgccggaaggcggc	CRISPR spacer
cgcgcacctactgctcggaccgctgccggaaggccgc	Protospacer
*  . *..******** ***************** **

160. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP030074 (Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccacgccccagcggcccgcccacgcggccgagc	Protospacer
***..  ****** * ***************.* 

161. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP032322 (Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcgg----ccgggg	CRISPR spacer
atcgtcgccaagctggccgcccaggcggtgttcc----	Protospacer
..******* ************* ****    **    

162. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcgg----ccgggg	CRISPR spacer
atcgtcgccaagctggccgcccaggcggtgttcc----	Protospacer
..******* ************* ****    **    

163. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcgg----ccgggg	CRISPR spacer
atcgtcgccaagctggccgcccaggcggtgttcc----	Protospacer
..******* ************* ****    **    

164. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP032340 (Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcgg----ccgggg	CRISPR spacer
atcgtcgccaagctggccgcccaggcggtgttcc----	Protospacer
..******* ************* ****    **    

165. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcgg----ccgggg	CRISPR spacer
atcgtcgccaagctggccgcccaggcggtgttcc----	Protospacer
..******* ************* ****    **    

166. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP012915 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcgg----ccgggg	CRISPR spacer
atcgtcgccaagctggccgcccaggcggtgttcc----	Protospacer
..******* ************* ****    **    

167. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP016613 (Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

168. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP021449 (Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

169. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to CP023013 (Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

170. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP049790 (Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

171. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP049794 (Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

172. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP049788 (Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

173. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022766 (Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

174. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP021763 (Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

175. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP015116 (Ralstonia solanacearum strain EP1 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

176. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP016555 (Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcactttgcgcagg	Protospacer
****************.*** *** . **  .**

177. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP049792 (Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

178. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052069 (Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

179. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP016915 (Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

180. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP016905 (Ralstonia solanacearum strain KACC 10709 plasmid unnamed1) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

181. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP025986 (Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

182. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022769 (Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

183. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP015851 (Ralstonia solanacearum strain YC40-M plasmid, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

184. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022773 (Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

185. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022783 (Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

186. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022791 (Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

187. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022795 (Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

188. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052071 (Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcactttgcgcagg	Protospacer
****************.*** *** . **  .**

189. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022482 (Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

190. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP009763 (Ralstonia solanacearum OE1-1 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

191. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to CP023015 (Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

192. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022779 (Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

193. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052075 (Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcactttgcgcagg	Protospacer
****************.*** *** . **  .**

194. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052085 (Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

195. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052095 (Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

196. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052105 (Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcactttgcgcagg	Protospacer
****************.*** *** . **  .**

197. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052077 (Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

198. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052087 (Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

199. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052097 (Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

200. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052115 (Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcactttgcgcagg	Protospacer
****************.*** *** . **  .**

201. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052127 (Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

202. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052079 (Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

203. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052089 (Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

204. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052093 (Ralstonia solanacearum strain FJAT15340.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

205. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052101 (Ralstonia solanacearum strain FJAT15304.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

206. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052099 (Ralstonia solanacearum strain FJAT15304.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

207. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052107 (Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcactttgcgcagg	Protospacer
****************.*** *** . **  .**

208. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022781 (Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

209. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052117 (Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcactttgcgcagg	Protospacer
****************.*** *** . **  .**

210. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052125 (Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

211. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022793 (Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

212. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022785 (Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

213. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022787 (Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

214. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022756 (Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

215. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052129 (Ralstonia solanacearum strain FJAT1303.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

216. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052121 (Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcactttgcgcagg	Protospacer
****************.*** *** . **  .**

217. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052123 (Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

218. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052131 (Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

219. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to CP011998 (Ralstonia solanacearum strain YC45 plasmid, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

220. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052073 (Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcactttgcgcagg	Protospacer
****************.*** *** . **  .**

221. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052081 (Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

222. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052083 (Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

223. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052109 (Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcactttgcgcagg	Protospacer
****************.*** *** . **  .**

224. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052091 (Ralstonia solanacearum strain FJAT15340.F6 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

225. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052111 (Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

226. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052103 (Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcactttgcgcagg	Protospacer
****************.*** *** . **  .**

227. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052119 (Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcactttgcgcagg	Protospacer
****************.*** *** . **  .**

228. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052113 (Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcagg	Protospacer
****************.*** *** . **  .**

229. spacer 38.14|6410863|36|NZ_CP047147|CRISPRCasFinder,CRT matches to NZ_CP030863 (Streptomyces globosus strain LZH-48 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.778

gtccggt--tcgtcggcggccgcgagctgcgcggcggc	CRISPR spacer
--gcggtcgcggtcggcggccgcgagctgcaaggcgga	Protospacer
   ****  . *******************. ***** 

230. spacer 7.1|2587203|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP020556 (Streptomyces sp. Sge12 plasmid pSGE, complete sequence) position: , mismatch: 9, identity: 0.719

tacctcgtcctcgacgagctgtggcgcgtcct	CRISPR spacer
atcgtcgtccgcgacgagctctggcgccagat	Protospacer
  * ****** ********* ******    *

231. spacer 7.1|2587203|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP011869 (Pseudonocardia sp. HH130629-09 plasmid pLS1-1, complete sequence) position: , mismatch: 9, identity: 0.719

tacctcgtcctcgacgagctgtggcgcgtcct	CRISPR spacer
atcgtcgtccgcgacgaggtgtggcgccagat	Protospacer
  * ****** ******* ********    *

232. spacer 21.5|3866543|31|NZ_CP047147|CRISPRCasFinder matches to NC_013930 (Thioalkalivibrio sp. K90mix plasmid pTK9001, complete sequence) position: , mismatch: 9, identity: 0.71

cttgaaccccctcccgcaaatccggtccgct	CRISPR spacer
agccaacccgctcccgcaaatcgggtctgac	Protospacer
  . ***** ************ ****.* .

233. spacer 21.10|3866543|32|NZ_CP047147|PILER-CR,CRT matches to NZ_CP021082 (Deinococcus ficus strain CC-FR2-10 plasmid pDFI1, complete sequence) position: , mismatch: 9, identity: 0.719

cttgaaccccctcccgcaaatccggtccgcta	CRISPR spacer
cgccgacccccacccgcaattccggtccgggg	Protospacer
* . .****** ******* *********  .

234. spacer 21.10|3866543|32|NZ_CP047147|PILER-CR,CRT matches to MK496050 (Pseudomonas sp. strain FFUP_PS_41 plasmid pJBCL41, complete sequence) position: , mismatch: 9, identity: 0.719

cttgaaccccctcccgcaaatccggtccgcta	CRISPR spacer
ccgaaaccccctccctcaaatctggtctgaac	Protospacer
*. .*********** ******.****.*   

235. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to CP006880 (Rhizobium gallicum bv. gallicum R602 plasmid pRgalR602c, complete sequence) position: , mismatch: 9, identity: 0.719

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
atggcgagcgtcacgaaggaggccgcgaccgc	Protospacer
 .  .*************** * ***** * *

236. spacer 34.1|5756194|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP034351 (Streptomyces sp. W1SF4 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.735

ggatcgatcccgccgccccgcgccccgccgacgc	CRISPR spacer
cgacttggtccgccgccccgcgcccggccgccgc	Protospacer
 **.. . .**************** **** ***

237. spacer 34.1|5756194|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 9, identity: 0.735

ggatcgatcccgccgccccgcgccccgccgacgc	CRISPR spacer
ctgtcctggccgccgccccgcgccaccccgacgc	Protospacer
  .**    *************** * *******

238. spacer 34.1|5756194|34|NZ_CP047147|CRISPRCasFinder matches to NC_012811 (Methylorubrum extorquens AM1 megaplasmid, complete sequence) position: , mismatch: 9, identity: 0.735

---ggatcgatcccgccgccccgcgccccgccgacgc	CRISPR spacer
caggagccg---ccgccgcgccgcgccgcgccgacga	Protospacer
   *...**   ******* ******* ******** 

239. spacer 34.1|5756194|34|NZ_CP047147|CRISPRCasFinder matches to NZ_LR134451 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 9, complete sequence) position: , mismatch: 9, identity: 0.735

ggatcgatcccgccgccccgcgccccgccgacgc	CRISPR spacer
ccggcgatcccgccgccctgcgcaccgcgctcgc	Protospacer
  . **************.**** ****   ***

240. spacer 37.7|6409035|52|NZ_CP047147|CRT matches to NC_013449 (Streptomyces sp. W9 plasmid pCQ3, complete sequence) position: , mismatch: 9, identity: 0.827

ccggggccacggcgacctcgccgcgcagctcgcctcgcagttgcgaccctcg-	CRISPR spacer
ccggggccacggcgacctcgccgcgcagctagccgcgcag-aacgacaccgcc	Protospacer
****************************** *** *****  .**** *.   

241. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP021449 (Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

242. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP049790 (Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

243. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP049794 (Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

244. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022766 (Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

245. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP021763 (Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

246. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP016555 (Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

247. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP049792 (Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

248. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052069 (Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

249. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP016915 (Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

250. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022769 (Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

251. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022773 (Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

252. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052071 (Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

253. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022779 (Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

254. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052075 (Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

255. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052085 (Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

256. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052095 (Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

257. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052105 (Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

258. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP021765 (Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

259. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052087 (Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

260. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052097 (Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

261. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052115 (Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

262. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052127 (Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

263. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052089 (Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

264. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052093 (Ralstonia solanacearum strain FJAT15340.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

265. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052101 (Ralstonia solanacearum strain FJAT15304.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

266. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052099 (Ralstonia solanacearum strain FJAT15304.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

267. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052107 (Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

268. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022781 (Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

269. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052117 (Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

270. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022793 (Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

271. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022785 (Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

272. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022787 (Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

273. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022756 (Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

274. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052129 (Ralstonia solanacearum strain FJAT1303.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

275. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052121 (Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

276. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052131 (Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

277. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to CP011998 (Ralstonia solanacearum strain YC45 plasmid, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

278. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052073 (Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

279. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052109 (Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

280. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052091 (Ralstonia solanacearum strain FJAT15340.F6 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

281. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052103 (Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

282. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052119 (Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

283. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP016613 (Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

284. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP016905 (Ralstonia solanacearum strain KACC 10709 plasmid unnamed1) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

285. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP025986 (Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

286. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP015851 (Ralstonia solanacearum strain YC40-M plasmid, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

287. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022791 (Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

288. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022482 (Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

289. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052111 (Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

290. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP052113 (Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.75

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
atacgtcccgtgccccgagtcatccgcctgggcgac	Protospacer
.. *..* .****** ******** ***********

291. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP053984 (Achromobacter pestifer strain FDAARGOS_790 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.735

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
agggcgcaccagctggccgcccaggtggccgggg	Protospacer
.  *.   *************** *.********

292. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NC_011879 (Pseudarthrobacter chlorophenolicus A6 plasmid pACHL01, complete sequence) position: , mismatch: 9, identity: 0.735

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
tcatacgcccagctgaccgcctacgcggccaccg	Protospacer
 *   **********.*****.********.  *

293. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP040820 (Paraoceanicella profunda strain D4M1 plasmid pD4M1B, complete sequence) position: , mismatch: 9, identity: 0.735

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gctcacgcgcagctggccggccacgcggcgctgc	Protospacer
**.  *** ********** *********   * 

294. spacer 37.25|6409470|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP015867 (Streptomyces parvulus strain 2297 plasmid pSPA1, complete sequence) position: , mismatch: 9, identity: 0.75

cgccagcgaggccagcacgaggggggccatcacggc	CRISPR spacer
tgccagcgaggccagcacgaccggggcgaggcagac	Protospacer
.*******************  ***** *    *.*

295. spacer 38.15|6410936|36|NZ_CP047147|CRISPRCasFinder,CRT matches to NZ_CP015597 (Mycobacterium sp. YC-RL4 plasmid pMYC1, complete sequence) position: , mismatch: 9, identity: 0.75

cggtgcgcaggtacgcggcggccggctcgtcccacg	CRISPR spacer
cgccacgcaggtacgccgcggccgcctcgtcgtcct	Protospacer
** ..*********** ******* ****** . * 

296. spacer 38.30|6410861|38|NZ_CP047147|PILER-CR matches to LN997845 (Streptomyces reticuli genome assembly TUE45, plasmid : IV) position: , mismatch: 9, identity: 0.763

acgtccggttcgtcggcggccgcgagctgcgcggcggc	CRISPR spacer
ctgacgggcccgtcggcggccgcgggctgcggggcgga	Protospacer
 .* * **..**************.****** ***** 

297. spacer 7.1|2587203|32|NZ_CP047147|CRISPRCasFinder matches to NZ_CP024583 (Roseomonas sp. FDAARGOS_362 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.688

tacctcgtcctcgacgagctgtggcgcgtcct	CRISPR spacer
cggccgagcctggccgagctgtggcgcgtccc	Protospacer
.. *. . *** * *****************.

298. spacer 7.1|2587203|32|NZ_CP047147|CRISPRCasFinder matches to NC_023283 (Streptomyces sp. FR1 plasmid pFRL3, complete sequence) position: , mismatch: 10, identity: 0.688

tacctcgtcctcgacgagctgtggcgcgtcct	CRISPR spacer
cttggggtcctcgacgatcagtggcgcgtaca	Protospacer
. .   *********** * ********* * 

299. spacer 7.1|2587203|32|NZ_CP047147|CRISPRCasFinder matches to NC_023284 (Streptomyces sp. F2 plasmid pFRL4, complete sequence) position: , mismatch: 10, identity: 0.688

tacctcgtcctcgacgagctgtggcgcgtcct	CRISPR spacer
cttggggtcctcgacgatcagtggcgcgtaca	Protospacer
. .   *********** * ********* * 

300. spacer 7.2|2587264|32|NZ_CP047147|CRISPRCasFinder matches to NZ_AP022607 (Mycobacterium branderi strain JCM 12687 plasmid pJCM12687) position: , mismatch: 10, identity: 0.688

gaggccgctccggtcgtcacgaacatcatcga	CRISPR spacer
cgtcatgtcccggtcgtcacgatcatcgtcga	Protospacer
 .   .*..************* ****.****

301. spacer 21.10|3866543|32|NZ_CP047147|PILER-CR,CRT matches to NC_013930 (Thioalkalivibrio sp. K90mix plasmid pTK9001, complete sequence) position: , mismatch: 10, identity: 0.688

cttgaaccccctcccgcaaatccggtccgcta	CRISPR spacer
agccaacccgctcccgcaaatcgggtctgacg	Protospacer
  . ***** ************ ****.* ..

302. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to MG298964 (Streptomyces phage Alsaber, complete genome) position: , mismatch: 10, identity: 0.688

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
gagccaggcgtcgcgaaggacgacgcgaacgg	Protospacer
   ....*****.*****************  

303. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to MT711979 (Streptomyces phage Endor2, complete genome) position: , mismatch: 10, identity: 0.688

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
gagccaggcgtcgcgaaggacgacgcgaacgg	Protospacer
   ....*****.*****************  

304. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to KT186229 (Streptomyces phage Verse, complete genome) position: , mismatch: 10, identity: 0.688

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
gagccaggcgtcgcgaaggacgacgcgaacgg	Protospacer
   ....*****.*****************  

305. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to KT186228 (Streptomyces phage Amela, complete genome) position: , mismatch: 10, identity: 0.688

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
gagccaggcgtcgcgaaggacgacgcgaacgg	Protospacer
   ....*****.*****************  

306. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NC_041856 (Streptomyces phage phiCAM, complete genome) position: , mismatch: 10, identity: 0.688

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
gagccaggcgtcgcgaaggacgacgcggaccg	Protospacer
   ....*****.**************.*** 

307. spacer 34.1|5756194|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP025805 (Sulfitobacter sp. SK012 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.706

ggatcgatcccgccgccccgcgccccgccgacgc	CRISPR spacer
ggatcgatcctgcagccccgcgcccaaaccttca	Protospacer
**********.** *********** . *  .  

308. spacer 34.1|5756194|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP025806 (Sulfitobacter sp. SK012 plasmid unnamed3, complete sequence) position: , mismatch: 10, identity: 0.706

ggatcgatcccgccgccccgcgccccgccgacgc	CRISPR spacer
ggatcgatcctgcagccccgcgcccaaaccttca	Protospacer
**********.** *********** . *  .  

309. spacer 34.1|5756194|34|NZ_CP047147|CRISPRCasFinder matches to NC_020894 (Streptomyces hygroscopicus subsp. jinggangensis TL01 plasmid pSHJGH1, complete sequence) position: , mismatch: 10, identity: 0.706

ggatcgatcccgccgccccgcgccccgccgacgc	CRISPR spacer
tcgcccgcctcgccgcccagcgccccgccgtcgc	Protospacer
  ..* ..*.******** *********** ***

310. spacer 34.1|5756194|34|NZ_CP047147|CRISPRCasFinder matches to NC_017766 (Streptomyces hygroscopicus subsp. jinggangensis 5008 plasmid pSHJG1, complete sequence) position: , mismatch: 10, identity: 0.706

ggatcgatcccgccgccccgcgccccgccgacgc	CRISPR spacer
tcgcccgcctcgccgcccagcgccccgccgtcgc	Protospacer
  ..* ..*.******** *********** ***

311. spacer 34.1|5756194|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 10, identity: 0.706

ggatcgatcccgccgccccgcgccccgccgacgc	CRISPR spacer
aggagcgtgacgccgccccacgccacgccgacgc	Protospacer
.*.   .*  *********.**** *********

312. spacer 34.1|5756194|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP039965 (Pseudorhodobacter sp. S12M18 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.706

ggatcgatcccgccgccccgcgccccgccgacgc	CRISPR spacer
ggatcaatcccgacgccccgcgccaccttcaaaa	Protospacer
*****.****** *********** * .. * . 

313. spacer 34.1|5756194|34|NZ_CP047147|CRISPRCasFinder matches to KX522649 (Mycobacterium phage Bircsak, complete genome) position: , mismatch: 10, identity: 0.706

ggatcgatcccgccgccccgcgccccgccgacgc	CRISPR spacer
tcggccaacccgccggcccgagccccgccgacta	Protospacer
  . * * ******* **** ***********  

314. spacer 34.1|5756194|34|NZ_CP047147|CRISPRCasFinder matches to KX522943 (Mycobacterium phage Gompeii16, complete genome) position: , mismatch: 10, identity: 0.706

ggatcgatcccgccgccccgcgccccgccgacgc	CRISPR spacer
tcggccaacccgccggcccgagccccgccgacta	Protospacer
  . * * ******* **** ***********  

315. spacer 37.3|6408740|51|NZ_CP047147|CRT matches to NC_013449 (Streptomyces sp. W9 plasmid pCQ3, complete sequence) position: , mismatch: 10, identity: 0.804

cgtcacgccgaccaggttccccggatcgccgccgtgttgttgcgatcctcg	CRISPR spacer
tgtcacgccgaccaggttccacggattgccgccgtgttgaagccgggcccg	Protospacer
.******************* *****.************  ** .  *.**

316. spacer 37.16|6408664|36|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022482 (Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence) position: , mismatch: 10, identity: 0.722

gctcaccgtgtgcccggagtcatcggcctgggcgac	CRISPR spacer
tgacgcgcgatgccccgagtcatctgcctgggcgac	Protospacer
   *.*   .***** ******** ***********

317. spacer 37.18|6408815|36|NZ_CP047147|CRISPRCasFinder,PILER-CR matches to NZ_CP039905 (Agrobacterium tumefaciens strain CFBP6623 plasmid pAtCFBP6623a, complete sequence) position: , mismatch: 10, identity: 0.722

ggtgttccgctcgcggccgcgcgtcatggcgacgtg	CRISPR spacer
cgctttcccctcgcggcggcgcgtcatggcttccaa	Protospacer
 *. **** ******** ************  *  .

318. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP026091 (Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcaac	Protospacer
****************.*** *** . **  .. 

319. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcaac	Protospacer
****************.*** *** . **  .. 

320. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcaac	Protospacer
****************.*** *** . **  .. 

321. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NC_017575 (Ralstonia solanacearum Po82 megaplasmid, complete sequence) position: , mismatch: 10, identity: 0.706

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcaac	Protospacer
****************.*** *** . **  .. 

322. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP051295 (Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence) position: , mismatch: 10, identity: 0.706

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcaac	Protospacer
****************.*** *** . **  .. 

323. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcaac	Protospacer
****************.*** *** . **  .. 

324. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 10, identity: 0.706

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcaac	Protospacer
****************.*** *** . **  .. 

325. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 10, identity: 0.706

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcaac	Protospacer
****************.*** *** . **  .. 

326. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcaac	Protospacer
****************.*** *** . **  .. 

327. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP039340 (Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence) position: , mismatch: 10, identity: 0.706

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcaac	Protospacer
****************.*** *** . **  .. 

328. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP012940 (Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcaac	Protospacer
****************.*** *** . **  .. 

329. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 10, identity: 0.706

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcaac	Protospacer
****************.*** *** . **  .. 

330. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcaac	Protospacer
****************.*** *** . **  .. 

331. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcaac	Protospacer
****************.*** *** . **  .. 

332. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcaac	Protospacer
****************.*** *** . **  .. 

333. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcaac	Protospacer
****************.*** *** . **  .. 

334. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcaac	Protospacer
****************.*** *** . **  .. 

335. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP026308 (Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcaac	Protospacer
****************.*** *** . **  .. 

336. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP021765 (Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcaac	Protospacer
****************.*** *** . **  .. 

337. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to CP047139 (Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcaac	Protospacer
****************.*** *** . **  .. 

338. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to CP047137 (Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcaac	Protospacer
****************.*** *** . **  .. 

339. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcaac	Protospacer
****************.*** *** . **  .. 

340. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcaac	Protospacer
****************.*** *** . **  .. 

341. spacer 37.22|6409111|34|NZ_CP047147|CRISPRCasFinder matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

gccgtcgcccagctggccgcccacgcggccgggg	CRISPR spacer
gccgtcgcccagctggtcgcgcaccttgcgcaac	Protospacer
****************.*** *** . **  .. 

342. spacer 39.1|6417946|35|NZ_CP047147|CRISPRCasFinder matches to NZ_CP024314 (Rhizobium sp. NXC24 plasmid pRspNXC24c, complete sequence) position: , mismatch: 10, identity: 0.714

tacttcccggtcctgtcggaagacggcgacggctc	CRISPR spacer
gaaagcccggtcctgtcggatgacggcaactgtct	Protospacer
 *   *************** ******.** *...

343. spacer 40.3|6418296|49|NZ_CP047147|CRISPRCasFinder matches to NC_023285 (Streptomyces sp. F8 plasmid pFRL5, complete sequence) position: , mismatch: 10, identity: 0.796

tcgaagttgcagatggccgcgttgatgagcatgaaggatggcggtcgcc-----	CRISPR spacer
tcgaagttgcagatcgccgcgttgatgagcatggagatt-----tcccccagag	Protospacer
************** ******************.**. *     ** **     

344. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_LR594660 (Variovorax sp. PBL-H6 plasmid 2) position: , mismatch: 11, identity: 0.656

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
aagcccggcgtcacgaaggtcgacgagaacgg	Protospacer
   .. .************ ***** ****  

345. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_LR594667 (Variovorax sp. SRS16 plasmid 2) position: , mismatch: 11, identity: 0.656

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
aagcccggcgtcacgaaggtcgacgagaacgg	Protospacer
   .. .************ ***** ****  

346. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to NZ_LR594672 (Variovorax sp. PBL-E5 plasmid 2) position: , mismatch: 11, identity: 0.656

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
aagcccggcgtcacgaaggtcgacgagaacgg	Protospacer
   .. .************ ***** ****  

347. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to MF766045 (Streptomyces phage Daudau, complete genome) position: , mismatch: 11, identity: 0.656

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
cagccaggcgtcacgcaggacgacgcggacgg	Protospacer
.  ....******** ***********.**  

348. spacer 33.1|5746389|32|NZ_CP047147|CRISPRCasFinder matches to MT701598 (Streptomyces phage Sitrop, complete genome) position: , mismatch: 11, identity: 0.656

tccttgagcgtcacgaaggacgacgcgaaccc	CRISPR spacer
gagccaggcgtcgcgaaggacgacgcggacgg	Protospacer
   ....*****.**************.**  

349. spacer 37.2|6408664|52|NZ_CP047147|CRT matches to NZ_CP015446 (Streptomyces sp. S8 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.788

gctcaccgtgtgcccggagtcatcggcctgggcgacgttg--cgatcctgggcc	CRISPR spacer
gctcaccgtttgcccggagtcgtcggcctgggcgacgaaggcccgccttgag--	Protospacer
********* ***********.***************  *  * ..*.**.*  

350. spacer 37.2|6408664|52|NZ_CP047147|CRT matches to NC_004719 (Streptomyces avermitilis MA-4680 = NBRC 14893 plasmid SAP1, complete sequence) position: , mismatch: 12, identity: 0.769

gctcaccgtgtgcccggagtcatcggcctgggcgacgttgcgatcctgggcc	CRISPR spacer
gctcaccgtgtgcccggagtcggcggcctgggcgacgaagctgcgcctggag	Protospacer
*********************. **************  ** .. *. **  

351. spacer 21.1|3866299|31|NZ_CP047147|CRISPRCasFinder matches to NZ_CP006989 (Rhizobium sp. IE4771 plasmid pRetIE4771c, complete sequence) position: , mismatch: 14, identity: 0.548

ggtccagaagtcctcgccgaggaacgtcctc------	CRISPR spacer
--gccttgcctcctcgccgag----gccttctggacc	Protospacer
   **  .  ***********    *.*.**      

352. spacer 21.1|3866299|31|NZ_CP047147|CRISPRCasFinder matches to NZ_CP021126 (Rhizobium sp. Kim5 plasmid pRetKim5b, complete sequence) position: , mismatch: 14, identity: 0.548

ggtccagaagtcctcgccgaggaacgtcctc------	CRISPR spacer
--gccttgcctcctcgccgag----gccttctggacc	Protospacer
   **  .  ***********    *.*.**      

353. spacer 21.1|3866299|31|NZ_CP047147|CRISPRCasFinder matches to CP007642 (Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803a, complete sequence) position: , mismatch: 14, identity: 0.548

ggtccagaagtcctcgccgaggaacgtcctc------	CRISPR spacer
--gccttgcctcctcgccgag----gccttctggacc	Protospacer
   **  .  ***********    *.*.**      

354. spacer 21.6|3866299|32|NZ_CP047147|PILER-CR,CRT matches to NZ_CP006989 (Rhizobium sp. IE4771 plasmid pRetIE4771c, complete sequence) position: , mismatch: 14, identity: 0.562

ggtccagaagtcctcgccgaggaacgtcctcc------	CRISPR spacer
-cgccttgcctcctcgccgagg-----ccttctggacc	Protospacer
   **  .  ************     ***.*      

355. spacer 21.6|3866299|32|NZ_CP047147|PILER-CR,CRT matches to NZ_CP021126 (Rhizobium sp. Kim5 plasmid pRetKim5b, complete sequence) position: , mismatch: 14, identity: 0.562

ggtccagaagtcctcgccgaggaacgtcctcc------	CRISPR spacer
-cgccttgcctcctcgccgagg-----ccttctggacc	Protospacer
   **  .  ************     ***.*      

356. spacer 21.6|3866299|32|NZ_CP047147|PILER-CR,CRT matches to CP007642 (Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803a, complete sequence) position: , mismatch: 14, identity: 0.562

ggtccagaagtcctcgccgaggaacgtcctcc------	CRISPR spacer
-cgccttgcctcctcgccgagg-----ccttctggacc	Protospacer
   **  .  ************     ***.*      

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	3775404 : 3810036	45	Streptomyces_phage(28.57%)	capsid,protease,integrase,holin,terminase,portal,head	attL 3795448:3795465|attR 3819032:3819049
DBSCAN-SWA_2	6257097 : 6386481	98	Bacillus_phage(18.18%)	transposase,integrase,tail,protease,plate	attL 6323795:6323811|attR 6394424:6394440

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP047147|3775404:3810036|DBSCAN-SWA
ATCAGGCGTCCGGGCGGGGGGTGTGCGGCGCCGCCCATCCGGCGACGGCCGACGCGGCGGCCGGGACCAGGGCGAGGACGAACGGCTCCAAGGCGTCGGGCATGCCGGCGATGAGGGACGGGTCGTCGGTGACGGCGCCGAGGATGGCGAGGGCGGCGAGGCTCAGCAGGTACGTGGCGACCGAGCTGGCCTTCACCTTGGTCTCGATCGGGGCGGACGAAGCGGCCATGGTCAGGCCCCCTTCTTCAGCGCGGCGACCTCGGCGCGGAGCGCGGCCACGTCCTTGGCCAGCTGCCGCACGACGTCGAGGATGCGGTTGGTCTGGTCGTAGGTCTCCGGCAGGAAGCTCTCCGCCTTCCACGTGGGGTTGGTCTTCGCGGTCTTGGCCGTGGACGGCGCGGGGATCGCGTCGCGCTTCCACACCGCCTCGTGCAGTTCCTTCGCGTTCACGGGGGCCTCCTTGTCGGGGGTGGTGGGGGTGGGGGTCTTGCCGGCCGGGACGGAGAGGCGCTTGGCGACCCGCGTGCGCATCGACGCCATGGTGAAGCCGCGGGGATCGATCTTCCCCGGCTGCCACTCCAGGTGGCCGATGACGGAGGCGGCGTCCCAGCCGTGCACGCGGCAGATGGCGGCCGACACGCGCTCGATCGCGTCGAGCTGGGCGGCGGGCCAGGGGTCCTTGCCGTCGCCGAGGTTCTCGCACTCGAAGCCGTAGAAGCGGGCGTTGCCGTCGGTGTTCGCCTCGTTCGGCTTGGGCAGGGCACGCTCGGCGATGACCGCGGCGAGGACGTCGCCGTCGCCAGCGCCGGCGTGGTTGGTGCGGCCGTAGCCGACCAGGTGCACGCGGCCGTCCTTGGTGATGACGCCGTGGCAGAGCGGGCCGGGCAGCTGGGAGTGGCCGTCGCGGCAGATGCGCACCGAGGTAGCTGAGCCGGAGGTGACGGTGTGGTGGATCATCACGCCGTTCACCGGGCCCCAGGCGCCCTTACTGTTGCGGTTGTGGGTGCGCCAACTCCCCACCTCCACAACGGAGAGGCCCTCGTCGCGGAGGGCCTTGATGAATCTGTCCGCGGACATCGGTGGTGCCATGTGGGCTCCAGGTGTGCGAGGAGCCCCGGCCGACAGGCGGCGCGGGGCTCGGGTGGAAGGGGCGAGGTCTAGCTGCTGGCCTCGTAGCAGCCGGAGACGTGGAAACTCATGCCGGCGGCGGCCGCGAGCGGGTTCGTCTGGTCCCAGTACGAGGAATCGGGCTGGTTGGTGGTGCCGTTGACGGAGCCGCCGGCGAAGGCGCGGGCGGTACCGCCGTTGCTGGTCGAGGTTTCGCCGGTGCCGGTGACCTCTCCGACGCCGGCGATGCGCGCGGACACGGTGAGGCAGCGGGCCCCGTGGAACACGGACGATGGTGAAGCGGGGAGGCCGAACGCCCAGTTGGCGTTGGCCGCGCCGAAGGTGGTGGTGCTGCCCACGCTGAGCTTGATGAGGAAGTTCACCGTGCGGCCGACCTTGAGGTAGCGGCCGGTCAGGCTGCCGTTGCCGACGCTGGGGGTGCCGCCGGTCTCGGCGATCCACGTCGGGGTGTACTCGGTCCAGGCGCCGAGGAAGCTGGCGAACTGGTCGCGGATCTGCTCGTTCAGCAGGCCCTCGGTGACGATCTCGCCGGGGAACCAGGTGCGCGGAGCGAACGTCATCGGACGGCCTCCTGGCTCGGGTCGGGCCACGACGGGTCGCGCGGCGGTATGGGCGGCTCGGGCTGGACGGGGTTGCGCGGGTCGCCCTCGGCCCACCAGAAGCGGCGGCCCTCGATCTCGCCGAGGTCTGCGTCGATGGCGGCGACGTCCTCGGGACTGGGCACGATGAGCGGCACCCAGTCCCGGCCGCACTGGGTGCAGCCGAACCTCGGGTCGTCGGTACTCACCACGAGGCCGGTGCCGCAGTTCGCGCAGTCGGCCATCCACCGGTTGTCGTCCACCCGCGCGTAAGTGCCCGGGTCACCGGGGACGGTGTCGGTGGGGACGGGGGTGCGACGGCCGAGGTTGGCGGCCATCCACAGGTAGACCAGCTCGGCGCCCGGGACCTGCGACCAGTCCTCGCGCTCCTGGCCCTTGCGGGTCGGCGCGGGCGGCAGGTAGAGCGTCTCGGCGTGCACGACGGGGGGTTGGGCCACGGGGTCTCCTCAGTAGGCGATGCGGGTGGTGATGCCGAGGCGGGAGTAGTCGGGGTCGGCGAGCTTCCACACGCTGTCGGTGGCGGCGGCGCTGGTGTGGAACTGGATGAGGTGGCTGTGCGACCTGATGTTCTCGACGTAGCCCTCGACCATCACGCGCATCGAGGCGGCTGGGGCCTGTGCGGGCAGGCCGGTCACGGTGATGGCCGAGCCGATCTCGGCATCGAGGATGTCGAGGTACCGGGGGTGGGTGTACGCCTCGACGGGCACCTCGCGCAGCTCGGGCAGCGGGTTGCCGTAGCGAGAGACCATCCAGTAGGCGGCGGCCAGGGCCCCCGAGTCGGTCGTCTTGAGGATGTCCAGGGACTCCTCGTACTGGCCGAACGCCAGCACGCTCTCGGGTGCGGTGACGCGCTGGGTGGCGCCGCCGGGCCGGGCCGCGTCCACGATGTTGACGAGCTTCTGGTCGTCGTCGGCGAGCTGGACGCGGCTGGTTTCCAGGTCGGCGTAGTCGAGGACGACCACGTCGCTGGCCGGGCTCGGGTTGTAGCGGATGCCGCGGGACTGGTAGGCCAGCCCGTACCAGTCCCGCTCGGCCCACAGCCTGGCGGACTCGGTCTTCTCGACCTCCCGCATGCGGGCGAGGGCGGGCTGCCCGCCGGCGCCCTGCCCGGCGACGGGGTCGTGGAGGTCGCCCCAGATGGATACCGAGGACAGCCCGGCGTACTTGGCGAGGCGGGTGATGCGCGCGTCGGCGGTCTCCCCTTCGTGGCCGGTCGCGCCCGCCCCGTAGTGGGTGGCGAGGTTGGCGCCCCACGTGGAGTCGGTGGGGGCGTAGATCCCGACGTGCGCGATGGACCCGGACCACAGGCGGCTGCTGCGGTAGCCGCCGACGTGGAGGCGCCGCAGGTCGTACATGTGGGGCACGTCGATGGTGGAGTCGACCATGACGCCGTCGAGCCAGAACCGGTTGGAGCCGCGGTCGTAGACGAGGTGGTGCCACTGGTCATCGAGGATGCCGGTGGTGCCGCTGATGCCTTCGGCGATGAGGCTGCCGCCGATCCAGTCTGTCCACTCGATCATCAGGCCGCCGATGCTGCTCACGCCGATGACGATCTGCTGGTCGTAGTTCCACGACGACATGCCGAGGATGGCCCGGGTCACCTCGGTGCCCTTGAACCACGCCTCGGCGGCGAAGTAGTAGGTGCTGATGGCGTTGGCGACGTCGGCGCCCAGGTTCGCCACCCAGTACTTCCCGGCGGTGGCGGAGACGGGGGTGGCGAGCGGGGCCTGCTCGCCGGTGGCGGGCGGCCCGTCGACCGCGGCCATGGCCAGGGTGCCGCCGCTGCCGACCTGCGCACGGACGAGGGGCGGCTGCCCGCGGCCGGAGATGTCGCCGGCGCTGTTGCCGCTGGCCTCTGTGAGCGGGTAGTAGGCCAGGGCCCCGGAGGTGGACACCTCCTCGGTCAGCATCGGCCGCAGCTCGGGGAGCCTGTTGAGGCGCTTGAACAGGTCGGTGGCGCTGATGGTGACGCTGGAGTGCAGGCCCTGCCAGTCGACGGGGAACTCGTTGACCATGCCCCAGAAGCGGGGCCGCACGGTGGCGTTGACCAGGTCCCATTCGACGTAGTCGGTGGCGCCGCCGGTGCGGGTCGCGGAGAAGTCGACCAGCACCGTCTGGCTCGTCACCCAGGCCGGGGTGGCGAGGGTGCGGCGCGTCGTCCAGATGAAGCCGTCCCGCGAGGTCTCCCAGCGCAGGGTGCCGGCGGACTCGCGGACGCGGAGCCAGGCGTGGTCGATCGGGGAGTACGGCAGGGACACCGCTGCCCCGTCGAAGTACGCCGTCTCGGAGGCGAGGCGGAGCTGCCCGGTCACCGGCGAGTACGAGAATCCCAGCCTCGTGCCAGCGGTGGTCGACAGCACCCACATCGACGCGGATGCCGAGGAGGAGCCGTTCGCGGCCGGGACCCGGGCGAGCTTCGCGGACAACTGCGAGCCGTTGAGCCGCCAGACGCGGGCGGACTGGAACCCGGCCACCACGCCCGAGGCGAGCGGGACCCGGGCCCGGCCGCCGGTCTCGGTGCTGCCGCCGTACACCGATGGCCACAGCGCGGTGCCGATCCGGTCGTCGTCGAAGTCGTCGCCGAGCTGGCCGAGCGGCCAGGTGGGGCCCGCTCCGGTCCGGGTGGGGATGATGGCCACCGCCACCCGGACCGGAGCGTTCCTGCGGACGAACGGGTGGAACGGCGACGCGGCGTTGCCGGGGGTGAGGGCGCCGTCCTGGTTGTCGAGGGTCATGGTGCACGACCCGGGCTGGGTCTCCGACCTCTCGTCTGCGGCGCCGCGGGTAATGCTGATGCCCTCGGTCATGGACACGCGGCGGCTGATGTCCGTCCACGTGATGGACCACGGGTACTGCACCACCCCGCCCCAGCCCACTTCGACCAGCAGAGCCACGACTACCCCACCCCCAGGTTCACGTTGACGCCGTGCGACCGCTTCAGGTGCAGAAGGGTCCGCTGGATCTCCCGGCCCACGGCCACCGGGTCCATCGCTCCGTGGACGTCGATCTGGATGGACACCGGCTGCCCGCCGACTGCCCCGCTGCCGTGGGTGACGGGGCGGCCGATGACGGGCTGGACGCCGGAGACGGCCCCGGCGACGCCGACCATGGCGCGGTCGACGGCCGGGCGGCCCTCGGTGAGGCCAACGGCCAGGCCCTCGCTGGAGTACCGGCCGATCTCGGCGAGGACCCGGGACGGGCTCTTGATGCCGAGGGCCTTGCGGATCGCCTTCTGCATGCCCTTGGCGATCTTCTCCATTTGCTTCTCGATCGCCTTCTGCTGGCTCTCCAACCCCTTGAGGAAGCCCTTGCCGGCGTTCTTCCCGGAGTCGTAGAGGGCATCGGCGCCGCGCTTGCCCAGCTTCTCCGCCTCAGCGTTGATGGCGTACTGGGTCTTGTTGATCTCCTTGAACGTCGCCTTGTCCGCGCCGGCCAGAGCGGACGCGTAGGCGTAGCCGTCCTCCGGGCCCATTTCCATGATTTCGCGCAGCATCGTCTTGTTGAGGCCGCGCTTGGCGAGGGTCTTGACGAACGCCGAGAACTGCTTGATCTTGGCGAGCTTCGCCTTGAGCTTCTTGCGGATGTTGCCCGCCGACACCGTCTCCTCGGAGTCGAACATGGCGCCCAGGGAGGCGGCCTTCTTCGCGGTGACCCGCGAGGACTCGGCGAAGTCCTTGGCCCGCTTGATGGTAGCGGCGATCTTGTCGCGTTCCTTCGCTGCGGCGAGGAGCTTGGTCGTCCCCTTCTTGATCTTCGCGACGAGCTTGTCGTCCTTCGATCCGGTGAACGCCGCGTAGATGTCCTTGCTGATCGCCTTGGCCGTGGCCTTGATCTTGTCGCGGGAGCCGGTCAGTCCGTCGATGAAGCCCTTGCCCGCGTGCTTGGCCAGGGTCTTCGTCTTCTTCGACGGCGACGCGATCTGAAGCTCGGCGCGGACGCCGGCCTCGACCGCGGACGCCATCACCCGGGCCGCCGCCTCGACGGTCCCGGCGGCGCCGGTCATGCCGACGGCCAGGCCCCGAGCGGTCTCCCGCCCGGCCCCGCCCATCGCCCCGCCCGAGGACATGGCGCTCATGCCCAGGCGGCCCTCGTTGATGGCGTTGAGGAACGCCAGGCCGTACCGGGCGACCGACCGTGCGCGGACGACGAACTCGCCGTTGGACAGCCTGGTGAGGATGGAGTCCGACGTGCCGGACCCCGGGCCCTCGACGTAGCCGCCGGGGCCGCCCACCCGGCCGCCGGCGGCCTTGAGCTGCGCGCCGTAGGAGCCGGACTTCCGGGCGGCCGAGCCGTCCCCGACTGTGACGTACCGGGTGGTGACCGTCACCGACCGGTCCCGCAGAGAGGCGAGGTCCGCCTTGGCCTGCCTGACCTTCGCCTGAAGGTCGCTGATCTGCGCGCGCACCGCTGCCTTGCGGGAGTCGGGCACGCTCGCCAGCTTCGACTTCGCCGAGGCGAGCTTGGCCTGCAAGTCCTCCATGTTGCCCTTGAGCTGCGCCGTCTTGTTCGGCGTCTTGAGGATCTGGCCCGCCAGCTTCCGGGCCTGCGCCTCGGTCAACCCCATGGCCTGCGCGGACTTCACCAGCTCGCCACGGCCACGGGCATAGATCGCGTTGACCTGCGACCAGGACTGGCCACCCTGCCGCGCGGACTCGGCGGCCTTCATCGTGGCGGACGCGAGGTCGTCCAGGGCCTGGTTGTTGGCGCGGCCCTTCTCCGTGCCCTCGTCCAGCGTGCGGCCGTTCTTCTTGATGGCGGCGGTGGCCGCGTCGATGGCGGCCTCCATGCCGCGGATGCCGCCGCGCGCCTGGAGGTACTGGTTGGACAGGGCGTTGATGGACTGGGCGAGGCCGTCCGCGCTGCGCTTCTGCGTGTCCAGCTTCGCCTGGACCTGCTGGGCCTGCGTGCCGAAGACGCCCATGGCCTGGGCGGCAAGCTGCTGCTCGACCTTGGCGGAGGCGAGGGCGGCCTTGTACTCGGGGAACGCTGCCGCGATGTCCTTGGTGGAGGCGCCGTTGTCCCGCATGGCCTGCGACACGGCCTCGAACCCGGACGCCGCCTCAGCCGCGTGCCCGGACGTGGCCATCTGCGCGAGGGCCTTGTCGACGCTGGCGAGCTTCTCCTTGGCCGCGTTGAAGCTGCTGTCACCACGGATGAGGCTGTCGAGCTTGAGGACCACGCCGTCGGCGGCCTTACCGAGACCTACGAGGCCGGCCCAGTCGCGGACCGAGTCCAGCTCGGCCATGTCGCCGCGCACCTGGCGGGCGGCTTTGCCGATGCCGTCGAGGCCGCCGAACACACGCTTCAGCTCGCCCGACTCCTTGCCCGAGGCCGCGAGGTTCTTGAAGCTGGTGGCGAGCTTGTCGACGTTGGGCGGCGTCGTCTGCGCCATGCTGTTGAGCTTGCCGAGGCCGATGAGGAGCAGGCCGATGCCGGTACCCGCGAGGGCCATCTTGGCGGTGCGGGACAGGGCGGCGATGGCGGCGCGGGCAGCGGCCAGCCGACCGGGCACGCCACCCGCTGCGGTCTGCATGGCGACGAGCTGTGCGCCGAGCCCGGCCAGTGCGGTGCGCGCGGCGGCCCCGCCCGCCGCGGCGAGGTTGACGGCCTTCACGGCGATGGCCAGCTGGAGCAGCATGGTGATGGCCTCGGGCGGCGCGGCCGCGACGATGCCGGAGATGGCGTTGACGATCTCCAGGGCGGACACGCCGACCTCGGACCCGGCTCTCAAGACGTTGATGACGGCCCTGCCGATGTTGGCGAGGGTGTCGGCGACGAGCGGGCCCTGGGCCTGCGCGTACTCCATGAACTCCCGGGCCCCGGGGGCGATCTTCCCCGCGTCGCCGCGACCGGCGTACAGGTCGACCAGCCCACGGTTGACCTTGGCGAGGGTGCCGGTGGCGAACTTCTCGAAGCGACCGACGGCCTTGTCGAAGCCGGGCGTGTTCATGGCGCCGGCCGCGATCGTCATCATGCGGTCCAGCTCGGACGACGTACCGCGCACCAGGCCGCTGGTCTTGGGCAGCAGGCCGGACGTGATGGCCAGGCCCTTGTTGAACGGGGCGAGGGTGTCCTTGGCGAGGTCGTCGCTCCAGTCGGCGTACTCGTCCTTGAGGACGCCCAGTCCGGCGGCCGCGCGGCGTGTGGCCGGGGGCATGTCGGCCAGCAGCCGGTGGTACTCCTCCTCGGCCTGGACCGCCTCCTGCGACGCCCGTCCCGACTTGGCGACGGCGTCCGCGTACTTCTTCTCCGCCTCCGACGCCTCGGTCATCGCCGAGACCTGGGGGCCGAGTGCGAGGGCGTAGGCCCCGGCGGCGACCGCGGCCGCGCCGGTCCCGGCCACGATCGGGGCCAGCGCTCCCGCAGCCGCTGCGGCGGCGGGGATCGCCGCGGGGGCGAGGGAGATGAGGCTGCCCTTGAGGGCTTCGATGGCGCGGCCGCCCGCGTCGGCGTCCCGCTCCATGTCCGCCATGCGCCGCGCGGTGTTGCGGCTCAGGCGGTCCATCGCGGAGGAGGACACCGTCGCGGCCGCGACCAGGCGGCGCTCCAGCCGGCCCGCGCTGGTCTCGACCCCGCGCAGGACGCGGGACAGCTGGTCGCGGCCGGCGAGGACGAACGTCATGCGGTGATCAGCCACTACTCACCTCCGGGTATCGGGACCTGGGCGGCGAGGTGCCGGTCGATCCAGGCGGTCGCGGAGGTCAGCTCCTCGCGGGAGAGGTGGCCGATCTCCCACGGGCGGATGTGCAGCAGGTTGGCCAGCGGCCACCTGTACTCGGTGATCAGCTCTTGGAAGCCGCCGGCTTCTTGGCGGGGGCCGCGGCTTTTGGGGAGGTCGCCGCGACGGCGCGGTCGACGTCCTCGGGGTCGTCGGCCAGCGACCGCAGGTGCTCCAGCACCTCGTCCCAGCCCGCCCCGCCCGCCTCGCCGCTCCGTCGAAGGTTGCCGACCATCTCCTCCAGGTCGGCCAGCTCCAGCCGCGCGGTGAGGCGGCGGCGCCACGACGGCAGGTCGAACTCGGTGAAGCGCAGGTTCCCGGCGGAGCGCTTGCGGTGAACCCACAGGACCGCGCGCATGGCGGTCGGGGACTCGGCGCGCAGGGCGGACTCGACGCCGTCCCAGGTTTCGCCGGTGACCTTCTCGACCTCGGCGGACTCCAGGGCGGACAGGTCGTCGGTGCTGACCGACTCGACGGTGCCGTCCTCGTGGCGGTACGACACGAGCATGGTGATCTCCTAGTTCAGGCGGCGGCGCACGTCGTCCACGACGCGCTCCACCTCACGGGTCATGCGGGGGGTGTGGGCGCGGACCGTGCGGTCCCACCACAGAGGGCTGGCGTTCTGCTGAGCCCAGCGGCTCTTGTTGCCGAACACGGGGTGGCGGACCTTGCCCTCGTTGATCTGCTTGAGCAGGCCGAACGTGATGTCGTTCGGAAGCCGGTCGATATCGATCCAGACGCGAGCGCCCGCTCCGGCGCCGGTGTTGCGGACGCTGATGCGGATGGCGCCCGCGATCGTTGCGCGGAGCGGGCGGGTGGTCGGTGACTGGCCGCCGCGCTTGCCCGGCTTCCGACCGGCAGAGGTCAGGTCGAGATGGCGAATGGAGTCCTGAAGCGCGCCTTGCAGCGGCTCGGCCGCGCGGCGGACGCGGCGCTGCATGCTGGCGCGGATGTTCTCGTTCCCGGCCGCACGCAGGCGCCGCTGAAGCTCCAGGAGCTGGCCGGTGCCGAGGATCTGCACGCGCACGAGATCACCTCACAGGGTCTCGTCCGTGGACATGTACTCGACGGCGATGGGGTTCGTCCCGTCCGACAGGGCGGTGAAGTTGAACGTGGGCTTGACCAGGTCGAAGCCCTCGACGGTGGGCGGCGCGTCGTCCAGCTTGATGACGGGCAGCTTGACCGTGAACCGCTCGTAGTGGGTCGCGGCGATGAGGGGGCCGGTGAAGTCCCAGACGAGCGACACCCCGGCATCCGAGGTGTGCAGGTCGTCGAGGATGGTGTCGACGTAGTCGCCCTCCAGCGACCCGGTGACCTTCACCTGGTCGTTCGAGATCGGCTCGGCCTTCAGCGCGGAGCTGTTGGCGTAGAACCGATCCGTGGCCAGCGGACGCTCGATCTTCACGGACACCTTGCGGATGCCCTGCCTCACCGTCTCCGAGCCGTAGGCGCCGGTCTTCACGCCCATCTGCCCGAAGTGGAACGGCGACATCGCCGGGTACGTCGCGACCGCCAGCGTCTGCGTCTCGTCGCAGTCCTTGCTGTCGATCTCGAAGCTCGCGGTGAGCATGCCGCCGACCTCGCAGGAGAACTCCGCCGACACGATCTTGCAGCCCGTGAACGTCTTGTCAGTGACCACGCCTGTGGTGAGCGGGACGCCCTTCTGGATCGTCAGGCTCTTGCCGAACACGTCGGCCAGGATGTGCGTCTGGAGGTACGCGTCGGTCGATGCCTGCTGCGTCGGTGTGACCGTGGTGCCCATGAGGGACTGGAGCAGGACACCCATGCCCTTGTTGGTGACCTCCATCTCCAGCGACCCGGACGCCTCCCGCTGGGTGACGACGCGGCGCGAGGCCAGCGGCACCAGGCGGCCCGCGGCGATGCCGGCGGACTGGGCGGTGGTCTTCTTGAGCTGGAGCCCCTCCTTCGTGAACTCGATGAACTTGGTGGGCGGGACGGCGGTGCCGTAGACGGACTCCGCCGCGATGCCGACTTGGGCGCCGAGCCCGGAACCGATCGCCATGTCAGCTCTCCTTCTGCGACTTGGCCGCTGCGGCCTTCTTCGCTGGGGCGTGGCCCGGCTCCTCCACGGACTCCCACGTGCCGGGCTGGCACACGTAGCCCTCGAACCGAGCGTCGGGAACCTCGACCACTTCGTCGGGCTCGACGGACCGGCCGCCGAGTTCCGGCACGGTGACCGGCTCCCGGCCGATGAAGCGCACACGCGCCATGACGTCCTCCTGGTGGTGTTTCAGATACGGGCACGGCACGAGACCGTGAAAGCGAGACCGGCCAGCGAGCCCTCGGAGTCCTGGACCTGGTCGAGAGCGCCGGCCGTCAGCTCGGACCACAGGACCGTCCCGCCGAGCGTCGGCGCGGCCGGCGCCGCGTCCGAAGCGCGCAGGACCGCCTCGACCGTCGCGACGATCTCGAAGACCCGAGCCCGGCGCAGGGCCATGTCCTTGTCGCCCGCCCGGGACTCCGCGTAGCAGGAGATCGAGAACGCCTCGTCACGCCGCCGGGCTCCGGCGACGGCGAAGTTTTGTTGCAGGTCGACGGCTTGGTCGGCGCCCGGCGACCAGCCGATGTACAGCCGGTGCCGGTCCGCCGACTGCTTGGTAGACGGAGGGCCGTCCTGGATGTGCACCAGCTCCAGCGCGGGCGAGCCGCGCAGGAGCGCCAGCAGCGCGTCGACTGCGGCCGGGACGCGGGAGGTCGCCTCCATCACGCCACCCCCGGCGGCAGCTTGAACGGCTCCAGCAGCTGGAGAACACGGTTCGGTACGGCGTACCCGAAGCCGGGGATCGGCTCCGTAACGGCGAAGTCGTCGGCCCCGCCCATCCCTCGCGCCGCCCCGTTCTGCGTGCGCCACAGGTGTTGGAGCAGCATCAGGGCGGCGAGGCGGATGGTGGGCGGGACGTCGGCGCGGCCTACGGTGTAGGCCACCGTCCACGCTCCGGCCGGGACCGGGGCGCCGTCGCGGCGCCGCACAACGCCGGCGGCATCCACGCTGAGGGTGGCCGTGTCGAGGCCGGGGCCGCCGTCGTAGGGCTCGGCGAGGGTGACGGACAGCACGGGGGTGGTGAGCAGGATGAGCGCGCCACGGTGCGCGGTGACTTCCTGGGTGACCTGTCGCGGCTCGACCGCCCCCACGTATCCCTCGATGACCGAGGTGAGCGCCTCGACGTACAAGCCCAGCTCGGTGTCGTGCCGTTCGGTGTCGATGTCGAGGTGGGCACGGGCCTCGGCGAGGGTGACCAGAGCCACGACCGTCCCCCTTCTACTCGCCGCCCGGGGCGGGCTGCTTGCGGCGGGTCCGGCGGGCGGTCGTCTCGGCGGGCGGCGTCTCCGGCGTTTCGACGGGCGAGGTGCGGACCAGCTCGGCCCGCACTCCGTCCGCCCACTTGGCCGCCTCGGCGCCGGGGAGGTCGATCTCCTCCCCGGCGCGCCAGGAGAAGCCTGCGCCCGCCACGCTGGTGAGCATGCGGATGCGGGCCATCAGTCACCCAGGCCCTGGTGGCGGTCGGTGACCTCGGCCTCGGCGCGGGCCTCGGCCGCCTCGGCGGCCTTCTCCTGCGCGTCCTTCAGGGCCTTGATGTCGGGGTCCGGGTCGGCGCTCTCCGCGCCGCCCGCGCCCTGCCCGGCGGTGACGCCGCGGGCGGCGACGTCGACCGCCGAGGTGGCCTGGACGGCGAGCTGCTCCTTGGCCGCGGCCAGGGCCACGTCCTTGTCGCCGATGAACTCGGGGTCGACCTGGTCCATCGAGCCGTCGGCGCGGCGCGAGGCCATGACGATGCGGTCGTGGTCGCCGCGTTCGGCGGCCGTGGGGGTGGGCTGGTCCTGGAGGACGCCGGAAGCCCCGGCGTCCTTCTTCGGCGTGGTCGCCATGTGCTGCTCCTTCTGCCGGTGGTGGACGGTGAACGGGCCTGTCAGGTCGCGGCGTTGCGGTACGCCTTGTACGCGGCGGTGTCCTGCGGGGTGCCGTCGGCGCGGGCGAAGGCGAGGAAGCCGACCTGGAGGAAGTCGGCGTACCGCTCGGACAGGCGCAGCAGCTGCACGTCCTGGACGTCGCGGATCAGGTAGCCGGCGTACAGGTCGCCGAAGAGGATCGACCGGGCGTTGGCCGCCATGGCGGGCATGTCCTGGTTGACGGTGTACTTGTAGCCGAGCAGCGCATCCGGGACACCGACCTGCACCGAGGGCTCCCACAGCGGGCGGCCCTGGCCGTCCTTGAGCTTGCGGGCGGTGGCCAGCGTGGTGTCGTGCAGCATCCACCCGGCGCGGCCGCCGAGCCGGTACGCGGGGTCCACGGAGTGGATGAGGTCGATGAGGTCGTCGTAGGTGACCGACGTGGTCTGGCCGGCGGCGCCGGTCTTGCCGATGCCCGCGTTGGTCTGGACGCCCTCGGGCTGGTTGGTGCCGGTGCCCGTGGTGAAGTGGGCGTTCTGCGCGCGGCCGATGCGCTCGCCGAGCTTGCGGGCCAGCCACGACTCGGCGTCGAACGCGTTGTCGTTGAGGAGCTGGAGGCTGACGCGGACGAGCTTGGAGGTGTAGGTGTAGGCGCCGATGTCGGCCTGCCCGAACGTCACATCCTGCTCGGTGACCTGGGTGTTCTCCGCGAGGATCGCGCCGACGTTCGCGGTGTCGTCGGCGGTCGGCCACGGCAGGGTCGCACCGGTCTCGGTCGTGATGACCTCGGCGGAGTCCCGCATGGAGGAGAGGAACTTCTGCGCCTCGGCCAGCTTCGCGCGGAACGCGGGCGGGACGAGGTAGCCGCCGGCCGCGCCGGTGGCCACGCCCTGGGCGCGCAGCTCCTTGCCGTCGACCCAGCCGGTGCGCAGCGCGCCGCGCTCCTCGCCGGACAGTTCGGTGGCGCCGTCGCGCATCCAGGTGCGCCACGCATCCGCGTAGGCCGCGGCCTGGTCCGGGCCGCCGTGCCGCTCGTCGTCCTCCTCCTTGGCGGCCTGGATGACCTGGGTGTAGTCGACGGCGGCGAGGCGCTGGTGGCGCTCCTCGCGCTCGATGTCGGTGGACAGCCGCTCGACGTCGGCGAGGGCGGCGTCCCAGGCGGACCGGTCCTCGGCGGACATGTCCGTCTCGGAGGCCGAGCGGTTCTGGAACTCCTGCGCCTTGTCCCAGGCGGAGGCCCGCTGGTCGAGGAGGGACTGGAGGTTGGCCATGTGGTTCTCCCAGCACGAAGCGCCCCGTGCCGGTGCGGCAGGGGCTGAGGGTGGTTGTGGGTGCGGCTACCGGGCGAGGCGGTAGCGGGCGGCGAGCAGGTCCATCTGCCGCGCCTGACGGCTCCCAGTGGTCTCTCCCGGCTGGGGTGCGTCGTGGCCCCGAGTGGACTCGGCCGGCTCGGGGCGGAAGTCGAGAAGCTCCGGGCGCAGGGCGGCCCGGCGGTCAAAGGCGTCCGCGTTGCCGCGGGCGGCGAGGGCCACGCCGACGGACCGCAGTGCGGCGTCGGTGCCCTCGTAGGCGGGGAACGTCACGGCGGACACCTCGAACAGCTGCACCTCGCGGATGACGCGCAGCTCGGCCTCCATGTCGCCCTCGGACGTCTGGACGCTCACGGTCTCCCAGTCGTCCTTGACGGTGCGGAAACCAAACGACATGCCGGTGATGTTCCGCAGGTCGAGGTTGACGACGAGGTCGTTGACGTAGGTGAGGCGGGTGTCGAGGTCGGCGTCGACCGCCAGGCCCTGCGCGTCCTGCGCCAGGCGCAGGGAGCCGGCCGAGACACGGGAGACGACGAGGCGGGTGTCGTGGTCCACGAGGAACCGGGCGTCGCCCTCGGTCAGGGTCTTGGTGAAGGCGCCCGGCGCGATCTCCTCGTAGAACCCCCAGGTCAGGGGGTTGCCGATGGCGGTGCGCTGGCCGAAGACGGCGGCGTGTCCGGCGAAGCTACGGGCGCCCTGGCCGTCGTCGGCGGCGCGGAGCTGCACCCCGGCCGTGGCCAGGGCGAGGTCGCGGCGCTCCTCAGTGCTGCGGTTCATCGTCGCCGCCCTCCTCGGGTGGGGTCGGGGGGTTGAGCAGCCGGTGCGCGGCGGCCAGGTGCCGGGCGGCACGCGCCGCCCGGTCGTCGGGTTCGCCGTCGGCGGCCGGGGCCGTCGCGGTCGGGTCGGAGCCGAGCGGCGCCATGTACATCGGCTGGAGCCGCATGTTGCCCTCGCGGCCGCCGAGCGGGGTGAGGTCTTCCAGGTCCCGGATGTCGTCCGCACTGAACGCACCGGTGTCCCGCATGGCCCGGTAGAACGTCGCCCGCGCCGAGCTGTCACCGCGGAGCAGGCCGCCGAGCTGGTACTTGGCGTACTGCCGCGTCGGGTCGAGCAGCTCCTTGGTGACGCGCTGCTCGGTCGGCGTCAGCCACGTCGGCGCCAGGTCCCATGTCACGAAGCCCTGCGCCTGCTGCTCCAGGCCCGTGCCCCAGCTGGTCGACTTCTCCGTCGACATGAGCAGGAACGGCGGGACGCCGAACATGCGGGACACCTCGGTGACCTGGAACTGCCGCGACTCCAGGAACTGGCTGTCGCGGTACGGCATGGTCACGGGCTGGAACGAGGCGCCGGAGTCCAGGACGCCGATGTCGAGCGCGCTGCCACCGGACAGCTTCGCGTTCCAGGCGGCCTTGAGGCTGGCGGCCTGCTCACGGGTGAGGCGCTGCTCAGTCTGGAGAATGCCGCTGATCATGTTGCCGGAGCCGTACAGCTCCGCCGCTGCCTTCTCCGCCGCGATGCCCAGGCCGATCCCCTCGGCCGCGGCACGGACCGGGGAGCAGCCGGTGACGCCGTCATAGCCGAGGGCGGGCAGGTGCAGGATCTCCCGCGACGTGAGCCGCACACGGCGGCCCTGGTCGTCCTTGACCCAGAACACCTTGCCGCCCGGGTTGTCCTCGGTGGCCGGCTCACGGTCGACCTTCACCCGGTCCGGGCGGATGGGCCACAGCTGGACGATGTCGCCCGCGCCGTTGCGGATCTTCTGCGCGTAGGCGTTGCCCCACAACAGGCGGTGGACGTACAGCAGGCGCCACAGCTCGAAGCGGGTCAACTCCGGGTGCGGGTCCTCCAGCAAGGCCACCGTTGCCCGGTCCTTGGTCCCGGCGGCGTAGGTGTGCAGGGGCAGCGCGGCCGACACGTTCGCGATGACGGACACCGCCCGCCACACCGCCGGCATGCGCAGAGAGCTGGTCTCGGTGACCGCCACCCCGGAGGCGCCAGCGGAGCCGCCCAGCAGACTCAAGAGGCTCTCGGAAGTGAGGGGCACCTTGGGGTTCTCCACCGACGCGCGACGCTCGAACAGGCCGAAGAGACTCACTGGCCAGCCCCCTTACGGCGCGGGGCGGGCGGCCCGGATGCCAGCGCGCGCTCGGCGACGACGACGCCCAGAACGCCGCCGAGGATGAGCGCGGCGGGCACGTAGACGAGGGCGACGCCGGCCAGGGCCGCGGCGACGGCGAGGAACTCCAGCACGTACAGGAGGGTGGTCACCACAGGTTCGGCACCCCCTTCTCCTCTTCCACCTCGGCGCCGAGCCCCCACTTGGCGAGGGTCGCGGCGACGAGCGGGCTGATGTCGGTGTCCACACCGCGCCGGGCCCACGCCCAGGCGTCGCCCAACGGGCGCTTCTGCGCGCCGGCCAGCGCGGTGGCCAGCGGTGCGTTGTCGAGGTGGGAGAGGGTCTGGTCGGCGACGGCGTCGTAGAACTGGCCGCACGCGGCCGCCACGTCCCGCGCCTTCGGCTGGACGACCGTGACGCCCAGGCCGGTCTCCTCGTCCTCCAGGTCGGCGATGAGCGACCCGGCGGGCCCGGCCCCGTCCACCACCCAGCAGCGCGGGCCCCACTTCGCGTGCAGCTCCTTGGCGCGCTCCACGACCCAGCCGGTGCCCGGCCGGTGCTCCACCACCTCAACGTGCGTGCCGCCCCGCCAGGGCCCGGCCACGCAGATCGCCGCGTGTGACCGCTCGGGCGTCACGTCGATGGAGAACACCACGGGGTTCTCCGGGGCGCTCTCAGCGGCAGCCAGGGACCGCCACGCGTCCTCGCCGATGACCTGCCAGGTGTCCGCCTCGTCCGACGGGTACAAGCCGACGCCCAGGCGCTCGCGGGCGTAGCCGTCGCGGCTGAGGGTGGCCCGCTCGTTGGCGACCTTGTCCAACGTCAGCCTGTAGCCGAGGGCGGGGTTCGCCTTCAGCACGGCCTCGTCCGACGCCGGGTCGTCGTGCGCGGTGCAGTCGCTGGGGCACTCGGCCGCGTGCAGGTCGGCGGACCACTCGAAGTACGCCAGGCTCGGGTCCGGGGCGCCAGCCTCCAGAGCGGCGAGCGCGCGGCGGCGCAGCCGGCCAAGCTGCACAGACGGGGCACCGATGCCGGCGCTGCCCAGGTACCAGATCTGCGGGTTGTCGACGGCGGCCATCGTGGGCAGCAGCGCGTCCATGGCGTCGTCGCCGAGGATCATGTCCTCGTCCAGGATGTTGCAGTCGCCGGTGAAGCCGCGCCCGGAGCCCTTGGAGCGGGCGATGAAGCGGAGCGTCTGCCCGGTGTGCAGCTCGATCGACTCCTCGCCGACCGTGTACCGGTACGCCTTGACACGTTTGTGCAGGTCAGGGGTCTGACGGATTAGGCGCTCTACCCGCTTGAACGCGGCCTTCGCCGTCTTGAACTCGTGGGCGCTGTGCAGGATGAGCTGCTCACCGCCGATGAACAGGCCCCACAACTCGCGGGCCTCGATGATCCCGCCCTTGCCGTTCTGCCTCGGCACGTTCACGGCGACCTCGAACGCGGCCCAGGAGCCGTCGGGCTTCTCGCCCATGCCCACGCGGAGGACGTGCTGCTGCCACGGGTCGAGGTGCAGGCCCGCCCGCGCGGCGAGGTCGATGGCCTCCTGGCCCGCGCTGGACGCGGCCGACGGCGCGGTCTGGATGGGCGGGGTCTGCCAGCCGTACACCGAGGCGTCAGTCGCCGGCGGCGCGGGCGGCTGCTCGGCGCTTCGCTCGCTGCTCAGCAATGTCATCGACCGCATCCCCCTTCGCTGCGACGGGCGCCAGGCGGCGCAGGTCGGCCATGACGGCTCGGAGTTCACGCGCGGCAACGGCGCGGGCGGTGGGCGCCTCGGCCTCGTCCACGGACTGGGCGAGGCTGGTGGCGAGTTCGGACAGGCCGGGCGAGACCGGCTCGACGCCGAGCTGGTGGATCTCCGCGTTGACCGCGTCGGTGACCGCGCCCATGATCACCACCCCCGTCACCGTCAGTGATGTCACGCAGGGTGACGGGCCATGATTCGGCTGAACGTGGTTCACGCGGATTGGCCCTGCGATCTGGCCGCGCAAAAAATCGGGCGACAAGAGCTTTTGGGTCGCCCCCTCTGGCCCTGAAGATTGCTTCCGCTCTCCCGCCCGGCGCGCGCTCGCACGGGCCGGGCCGAGCGCATAGTCGCAGCTCAGCGACCTAGCGCGGCACTGCGTGACGTTGGGTCACCAGCGGCGGGATGCCTGCGGCATGGCCTCGCGTGGCCGGTTGCGCCGGGCGTTGTACCAGCGGGCGGCGACGCGGCGCATGGCCGGGTCACGCATGGTGTCGATGCGCTGCATGACGATCTCTTCGCCCGGGTCAACGGCGATGACCTTGGCCTTGAGGCGCTTGTACTTCGCCAGATGCTTCGGGCTGGGCATCGTGTGGATGAGGTAGACGTCAACCGTGTCCAGGTGACTGAGGGCCTCGTCTATGGCCGCGTATCGGGCGCGGAGAGCGACCCGGACGGCGACCCGGTCGTGATTCCACTGGGGCGCGCCGGGGCCGGTGAGGGCCCGGGTGATGCGGTCCAGGTCGATGACCACGTCACGGGCCTTGGCCCGTGCTTCGATCCACGTGCTCTTGCCCGCGGCCGGCGGGCCGGTGACGACGTACAGCACCGCTCACCACCTCCGTGAGGCGCGAGCGGGCGGGCGCGGCGTCATCCGGTTGCCCCGCGACGAGTTGCAGCGGCGGTGGGCGGCGCGGGCGTTGGCGGGGTCGAGGAGCTGCCCGCCGCGTGAGAGCGGCACCACGTGGTCGAGGGTGAAGGAGAGCGGGTGCCGGGCGTCGAGGCCGTGCGGGATGGCGCGCCCGCAGAGCCAGCACGGGTCGCCGCGACGCTTGAGGGCAGCGACGAGGCGGCGGTAGGGGCGCCCGTTGCGCGGGTTGGCAGGCACGGGCGCCTCCTTCGCTCATTCGTCCCAGAGGGGTTCGTCCGCGTCGGGGCTCGGGCTGAAGGGGTCGAACCCGCCGGCCTGTTCGGTGACGTAGTGGGCGAGGATGAGCTTGTAGTCCTCTTCCTTGAGGTCGTTGCAGGCTGCTGGCCGGTTGGTGACGGTGTGCTCGACGCTGAGCGCGGCTCGGCAGTCCTTGACGCTCTGGTCGTAGCTCTTGCCGCAGCCGGTGAGGAGCAGGCCGGCGGTGAGCGCGGCCAGGACGGTGGTGCGGATGCGCATGGTCCCCCCTGGGATCAGGTCCAGGGGGCATCGTGCGGCATGGAGCCACCGGGCGGGGTGGGCGTGGCCGAGTCGTGACACAGCGAAGCCCCCGACCGGGGGTCAGGGGCTTCGCCGTGCGTCTCGTACGCGGGCATGCCTCGCGTGGGTCGAGTGTTACACCGAGTGATCTCCCTGGTCAAGCTGCCGCAGCGGACCGGAGTGCGAGGCGCGCCCGGAGTTCGTGGAGGTCGATCAGCACGCGGCCGCGGGCGTCGTGGCCGTGGTGGGTGAGGTGGCCGCGCCGCAGCCACTGGCGGATGGTGCCGGGGCGGATGCCGGTGGCGGCCTGGGCGGCGTAGGCGTCCACGAGGAGCGGCTGCTGGTGCATGGCTCCATCCTCCTACAGGCCGTCCCGCAGAGCGCGCGACTGGGCCCGCCGCACACCCTGTTGCGGCGGGCCCAGGCTCGGTCTGACGGTCAGCGGCGGTCCTTCTTCCGCTTGCCCGGGACCGGCTTCTCGGTCGGCTTGACCCAGCCGCCCCTGCTCGCCTGGTAGGTCGTCTCGAACTTCTTCTTGTCCTCGTCGGACTGGGTGAACTCGGACAGTGGCATCGACTTGCGGAAGAGGCCCATGATGGGTGCTCCGTCTCTACTCGGGATGGGCCCGGGGCGGCCGGACAGCTGCCAGGCGGACGGCCGCCCCGGGGGTCACGCCACCTTGTGGTGACGGTGGGTCTCGGCGGGGTCGTAGATGGTCACGGTCCCCTCTCCGCGTACGACCCTCGGCGCGTCGCTGCTGCTGCTGTTGCTGTCCTGACCTGCAACAACAACGGGGGTGGGGTCGCCGCTCTCGGCCGGGGGGAGGGGTGGGAAGTTGCTGGCCTTGATGCCGGTGGAGGTGACGCCCCCCATCCGCACCTGACCGCCAGCCGGAATGCGGGCGGCCTTGAGGGCGGCCCGGACGCGATCGGCGGGGAGCTGCATGTGGGCGGCGAGGGCGGCCGTGTGAGCGTTCGGATCGGCCACTGCGCGGAGGGCCAGGGCCAGCTCCTCGCGGGTGGGTAGCGGGGCCTCGGCGGGGGCCTCTTCGGCGGCCTCGGCGGGGACCTCTTCGGCCACCTCTTCCGGCATCTCGGCGGGGGGCTCGTCGGTCTTCTCGGCGGCCTCCTTCTTGTCGTCCTTGGCGGGGGCCGGGCGCCCGGCCCGCCAGGCGGCGAGAAGGGCGACGCCAGCGACCACCCACATCAGGCTCGGGGTGGCCCTCACGGCGCGGGCGACGAGGTAGAGGCCGAGGGCGATCAGGGCGGCCCGGAGGAGGGTGCCGAGGTGGGCGGCGAGGCCGGTGAGGTCGTCGCGGTGCCCGCGACGCGCCCAGGCGGTCGCGCGGCGAGCGAGGGCGGGCCCGAGGCGGCCGGCGCCGCGGGCGAGGCGGTCGGCGGCGGGGCGGAGGCGGTCGGCGGCGCTCACAGGATGCCCGCCCCGGAGGCCGCGCTGCGCAGGTAGTCGCCAGCGATGTTGAAGGTCTCGGGGAGCCAGTCCAGCGCGGAGGCGATGCCTGCGGTGGCGCACAGGACCACGCCGACGAAGACGCCCCCGAAGATCCTCCGCTTGTCCGCCTTGGGCGCCAGCTTCCAGGCGAGGCCGACACCTGCGGTGAGGAGGACGACCATGACGGCCCCCTCGGGGGTGAGGGTGCCCATGCTGCCGCGTGGAATGGGGGTGCCTGCGCCGGCGCCGGTGAGGCCGGCGGTGACCTTGTCGCCGCCGGCGGTGGCACCGCCAGCGAGCCCGGAGGCGGCCCATCCGAGGAGGCCGGCGCACACGGTGCTCATGGCACCCAGGACGAATCCCTCACTGAAGGGGAGCAGGTCCTTGGGGGCGCGGCCGCCGCGCCACCAGGGGCGGAGGTTGGCCCAGGCGACGAGCAGGCCGACGGCGAGGCCGGCGAGGGTGATGGAGGTGGTCATCGGGGCACTCCGGTGAGCAGAAGGACGAGGTCGTAGAGATCGAGGACGCCGGTGGCGCCGAGCAGGGCGGTGGTGAAGGCGAAGCGGCCCAGCCAGCGCCCGCGGCGGTTGATGGCCCAGGCGGCGGCGAGGGCGACGGCGGCGATGAGGTAGGCGGCGGGCAGGCCGGCCTCCGTACGCGCGTCGTGGAGGGTGGCGGCCCAGGCGCCGACGGGGCTGGTGCCGTTTAGCCACGGCGCCAGGGCGGCGAGCACGGCGGAGAGCAGCTTCCAGTCGGTACAGCGGTCCCATAGCCAGTCCACGGCGCGCTGGGTGCGGGTGGACGGCGGGGGTTCCTCGCCGGGCGTGAGGTCGACGGTGACGTAGACCTGGATGGGCGGTGGAGGATCGGCAGGTGCTGCGGGGCCCGGCGCCCAAGGCGCGGGTGGCACCGGGGCCTTCCGCTGGTGCCAGGGAGGGTCGTTGGGGTCCGGCGGGCGGGGCGGCAGCGGCTGGCCGGCGGGGATGATCTGGCTCGGCGTGATGGGCTGCGGGTTGTCGGTCACGGCTGCACCTCGGCGTCGAGGAGTGCGCGCATCCGCTGGGCGCGCGCCTGTCCGATGCGCAGCCCGGACTGGAGTGCGCGGAGGGGTGCGGGGCGGCCGTGGTCGCGCCGGTGCTGGGCGTCGAGGCGTCGGGCGTCGGGCAGCAGCGCCCGGTCCGCATCCGCATCCGGCGCATCCGCATCCGGCGCATCCGCATCCGGCGTAGCCGGGTCACCTCCGGCCGCATCCGGGTCGCTGGGGTCGGGGATGCGGGCGTGGACGGTGGTGCGGGTCTGGCCTGCGGCGGGTGCGCATCCGGGTGCGGGCCGGGCGCCGGATGCACCGGCGCGGAGCGCGAGTTCGACCTGGGTGTTGGAGACGACGATGCCGAGGTCGCCCAGCAGGGCGCGCAACTCGTCCACCGTGACGGCCGGGTGCGCACCCGCGACGACGAGTGTGGCGTCGAGCGGGTCCATCGCGCGCAGCTCCCGGGCGGCCGCCGCCTCGGGCCGCTGGACGGGCCGGACCGGGTCGCGGGGCGGGTCCCAGGGCGAGGCGAGTTGCAGGGTGGGGAGCGCCCGGGAGTGCAGCCGCGTGGCGAGTGCGCCGAGGAGTGCGTCGCGCTGGGCGCGGGATGCGCCGACTTGGGCGCGGCCGACGGCGCGGTCGAGGCGGCGTTCGAGGCGGGCCCGGCGCCAGGCGGTGCCGCGGCCCTGCCGGAGGGCGAGCTGGGCGGCGAGGTCGACGGCGCGGGCGGTCCACCGGTCGCGGGTGATCTGCTCGGCGGTGCGCTCGCGGGCGGCGAGGCCGAGGCGGGAGAGGAGCCGGGCTCGCAGTTCGCGGCCGAGGGTGGCGGCGAGGCCGCCGGTGAGCGCCTCGGGGCGCCGCACGCGCACCTCCAGGCCCATGGCGAGGTGCCAGAGCAGGCCGGCCATGACGGGCCCGAAGAACGCTCGGACGGTGCCGCCCCACCAGCCGGACTCGGCGTAGGCCGGGACGATCTGAACGGCGGTGATGAGCCAGACGAGGGCGCCGGGGACGCCGGCGCTGCCGGTGCCCTCGTCTCCGGCGGTGGCGCGCTTGCGGGCGCGGGCGCCGATGGCGCAGGCGAGCAAGGCGACCTCGCCGGCGGCGAACATGACGGCGCGCTCGGCGAAGCGGTCCATACCGAGGTGGCTTTCCGCGAACCGCCAGCTCGTGTCACCGGAGTACAGGGTGCAGAGGGCGGCGGCGGCGCCGAAGACGAGGACGAAGCCGGGCGGCCAGTCGAGCCCGCGCAGGCGGCGGACGGCGGCCCGGAGGAGCAGGGCGAGGGCGAGGGCCACCACGAGGGTGATGGCCGCGGTGGGCCAGGGGTTCGCCCCGGCCCACCGCAGGAGCATCTCGGTCACCGGGCGCCGCCGATGACCTGGTCGAGGAGCAGCGCGTACTCGCCGCGGGTGATGTCGCGGTCGACGCGGGGGGCGAGGTCGCGGGCGGCGCGCTCGGCGTGCTCGGCGCGGGCGGTGCCGTAGCCGCAGCGGGCCTCGGAGAACCGCAGGAGGAGCGCAAGGCGGGTGCCGTCCCGCATGGGCTCGGTCGGCCGCTCGGTGCGGAGCCGCAGGGCGAGGCGGGTGACGAGCGCGACGGCGTCGAGGCGGATGGTGTCCAGCTGGTCAGTGGTCATCGGGCACCGCCGTTGGTGACGGTGCTACGGCCGCCGTCGGGGGTGCAGATGGTGGTGACCGTGCGCCCGGCGCGGCGGGTGATGATGCCGGCCGCGACGAGGCGGCGGGGCGGGGGACTTGCAGGCGCGACGGGGCGCGCGAAATGATCGGTCATGCCGACTCCTGCTCAGATCAGGTGTTCGGTCGAAAGGCCGGGCGGTGCGCGCGCCGGGGGGTCCAAGCCCCGAGCTGCTGCCCGGCCTTTCGTTCTCCCTCTACCGTTCCATAGCCTGAACGGAATGTCCAGCCTAATGAACGAGCTGGGCATGCCTCATGGCGTACCGGCGGGCTGGAAGTGCCGCAGCGTCAGGTAGTCCTCGGGCCCGTACGTCGTCCCGCACCACCTGCACGTCAGCCGTGTCTCGTCCGGCAGCCGCGTGATGACCGCACCGCACACCCCCTCCCCGCCGACCAGCGCCACGCAGTAGCCGAGCCGCTGGCGCCTCGGCTCCGGGTCGCCGACAACTGAGCGGGCCTGGCTGGTCAGCTCGGCCACCTCGCGGGCCAGATCCCCAGCGGCCGGGTACTGGGCCACCACCCAGTCGACCTCCTGCGCCAGCCACTGGCAGTCCCGGGCCAGGTCCGGATGGGGGGCCGAGCCTCGGTGAGGCCAGCGCAGCCGCCGGACCTCGGCCCGCCGAGCGTGGATCGCGTTGGTAGCGCGGGCCCAGGTCACCGTGTCCAGGACGTCCTCGTTGATGGGCGACCGGGGGCCGGCCGGGGCCTTGGTCGCCACGATGTCTCCCCACCCGCTCCGGCGGGGGACCAGGAACTCCCCGACCTCGGCGTAGAGGGCGGGAAGCGCGCGCAGCCGCGCGGCCAGCTCCTCTCCGTGCCGGGTGCACAGGTAGCCGCTGGTCGCGCGGTTGCACAGGTCGCAGGTCGTCACTTGGTGCTGGTCTCCTCAGGCTCTGCAAGGTGCTGCCGGACGGTCTCGGCGATGGGGTGCTTCGACGTGGTGTCCTTGACGACGACCTGCATGTACTCGTCCAGGTCGTCGCACCAGCCGGTGAGCCGGGAGACGGCGGCCTCGGCTCGCAGGGCTCGCTCCTTCCACCGGTCGCCCCTGCGCCAGCCTTCGTTGGCGTTGGTGTACAGCTCGTCCAGGGCGTCGTCGGTGATGTCGTTCGCGGTGTACCGGCGCTGGCTCATGCGGGTGTCCTTCCGGTGCAGGTGTTGGAGTGGGTGGCGCCGCGGCTCTCCCACCCGGGGAGGCAGCACGCGCCGTCGAGGGCCGCATAGTCGGCGCGCCGAGCGGCGCGGGTGGTGTGGACGCGGAGCGCCAGGCGGAGGTCGGCGGCGACGGCGCGGACGTACGTCAGCTCGGCCTCGCGGATGGCGGCGACCAGGAGCAGGCCGAGCACGACGACGAACGCTGCCGCCGTGGCGGGGGCGCCGGCCTGGGCGGAGACGACCGCGCAGTACGTGACCCAGGCGCCGCCGAGGAAGTAGCCGGCGCGAAGGAGGCGGGGACGGGTCATCGGGCGAACTCCTTCGGGAGGGCGGGCGCGGGGAGGCCGGTGGCCGCGGCGACGATGTGCGCGGCGAGGAGCGGCGGGACGGCATTGCCGATCTGCTCGAACTGCTTCGTCCGCGTGCCCTGCCACGGGTGGTCGACGGGGAAGGTCTGCAACGCGGCGGCCTCGGCAACGGTGATACGGACGGTGTCCGCGGGCTGGTCCGACGGCACCCAGGCGCAGAGGTCGGCCCGGCTGGTCATGGTCACCGCAGGCTGGTCGGCGCGGCGCTCGGCCCGGCCTTCGCCGGCTACCGACTGGCCCGACCGCAGCACCCACGACCGGGTCTTCTCGGTGAGCGCCCACGAAGGCCCGTCCGCCAGGAAGGCGTTGCCGCCCGGCGTGCGCCTCTCGCCTCGGGTGACGACGGTCTGCCCGTCGGGCCAGCCGAGGGCCTCGGCCATCGACACCCACCGGGCCCGGCCGGGCCCGAACAGGCCCGGCGTCATCGCCTGTTCGCTGTGCGTCGGCCCCGGGGCGGTGACCGCCCGGGTGCGGGAGGCGATGAGGATGGCGCGCCTGCGGGTCTGGGGCACGCCGTAGTCAGCCGCGTTGAGAACGCCGGCCCACACCGAGTAGCCCCGGCCGCGGAGGATGCCCGCGTACTGCTGCCACAGCGGCAGGACATCGACGACTTCCTCCATGCACACCCACTCGGGCTGGAGGTCGGTGAGCCACCGCATCGGCTCGGCAGCGAGCAGCGACCGCGGGTCGCGGCACCGTGCGAGCAGCTGGGCGCGGGTGTCGCGCCCGTGCGCGAGGTCGTGCACGGCCTGGTGGACGAGGGGCTGGTCAGCGAGGCCGCCGCGCTTGCCCGCCCTCGACCACGCCTGGCACGGCGGCGAGGCGATGAGGCCGGTGATGCGCCCGGCGACCGGGGCGGTTGGGTAGGTGGCGATGTCGCACTGGATGGTCGGGTGGCCGGCGGCGACGGCGGTGCGGCATGCGGCGGTGTCCAGCTCCAGGCCGATGTCGGTGAGGCCGAGCATCCGCAGGCCCTCGGACCAGCCGCGCGGGCCGGAGAACAGGTCCACGATCACCGGGTGGCCTCCAGGCACTCGCAGGTGTCCGGGTTGGTCCAGCCGTCGGCGCACCGGCAGCCGGGGCCGCCGGTGCAGCGGTCGCAGGGCTCGGAGTCGACGGGGGTGATGCGGGGGTAGCGGCGGCCGATCAGGGCGGGGGCGCTGATGGTGAGGAGGAGGGCGAGGCCGAGCCACGCGAGCGGGGCGTTCACTGGGACTCACCTGCCTTAGCCTCAGCGGCGAGGATGGTGGCGGGCGCCGGGTCGACGTGCGTCAGGGAGATGCACGCGCCGTGGTCCTCGACCATCACCACCGGGGTGTGGCCGCTCAGGACCCACGCGGCGGTACGAGTGCGGGTGACGAGCCGCTCGCAGTCTGGGTCGTCCTCCGGGCGGACGCCGGGGAAGGCGGTGACCGGCGTACCCACTGGGTGGGCGGCGTTCCAGGCATCCGCGACGGCGGTCGGGGTGGTCTTCATGCGGGTTCCTCCGTGGTGTGATGGGTGGAGGTCCGGGCCTGTTAGCGGCAGGCCCGGACAGTTACGCGGCGGGCAGGATGAGCTGGCCGAGGACGCCGTTCACGCGGTCCTGGTCGATGAGGTCGGCGACGTCGCCGGCGGATGCGCCGCGCGGCACGGCGATGCCCAGGCGCCGGCAGAGGCCGAGCTGCGCCGGGCTCGGGGGAGCGGACCGCCATCGCGCCTGCCGGGCGACGAACGCGCGGGGGGCGAGGGTCTTGGCCTGCTGCTCCAGCCACGCCAGCGCGTCGGGGAGCGGACGGGCCACGTCGTCCTTCGGGGCCTGGACACCGCCCGCCTGCGTCCAGCGGCGCATCCGGTAGAGGCGGGTCCCGGGGTCCCGCTGGAGAAAAAGGAACATCGCGCTCGTCAGGCGGATGAACCACACGCCGGACGGCGTACGGAGCCAGCGGATCGCGGACTCCCCGAAGAGGTTGATCTCCTCGGCCGCCACCCGGGCCGCGAGCGTGCGGCGCTTCTCGATGACGGCGGCCTCGTCGGCGATCTCCCGCAGGCTCTTGCCCTCCTCGGCCTCGCCCACCTCGCGGGCGGTGAGGTCGACCATGGAGGCCAGCTTGTGCCGGGTGGAAGCCCCGATGACGTCCAGGAGCAGGGCGTCCGTCTTCCCCGGCGCCGGGCGCAGTGCGCGGCCGGCCATCTGGACGTAGAGCCCGGGGGACTTGGTCGGCCGGGCGATCACGGCGCAGCTGGTGTGCGGGGCGTCGAACCCCTCCGTCAGGACCATGCAGTTGGTGAGCACCTGCACGTCCCCGGCCGAGTAGCGGGCGAGCGTAGCCCGGCGCTCCTCGCGGCCCATGTCGCCCCACACCGGGGCCGCGGTGACCCCGGCGGCGCGCAGTGCGTCGGCGGCGGCCTGCGCGGTGGCCACGGTCGGTGTGAAGACCACGCCCGGCCGGTCGGCCGCGTGCTGGGTGTACGCCTGGGCGATGGCCTCCAGGGCGCCGGAGTCCTCCAGGGCCTTGCCGAGTTGCCCGTCGACCAGGTCGCCGCCGCGGGTCCGGACCGTGTCGAGGTCGAGGGTGTCGACGGTGAGCCGCTTGCCGCGCACGTCGCACAGGTAGCCGTCGCTGATCATGTCGAGGATGTCGAGGGTGAAGACGACGTCCTGCCAGACCTCGGCGAGGCCGCCGTCGGTGCGGGTCATGGTCGCGGTGAACCCGGCGACGGGCACGCCGCGCCAGGCGCCGAAGTGCTCCAGCACCTCCATGTACGTGCGGGCGGCGGCGTGGTGGCACTCGTCCACGATCACGAGGCCGATGTCCCGGATGGCTTCCCGGCGGCGCGGTACGGCCAGGGTCTGGACGCTGGCCACGATGACGTCGGCGTCCTGGTGCTGGTCGCGCTCGGCCTTGACGATGCCGACGCGCAGCATCGGGTCGACGGCGAGCAGCTTGGCCGCCGCCTGCTCGATCAGCTCCTCCCGGTGCGCGATCACGAGGACGCGGTGGCCGCCGAGGGTGTCGAGCATCTGGTGGGCCAGGTGGCTGAAGACCACGGTCTTGCCGGCGCCGGTGGGCAGCACGACGGCGAGACGGTTGGTACCAGCGGCCCACCCGGAGCGGAGGGCCTCGATCGCGTCGACCTGGTAGGGCCGAGGGGTGAAGGTTGTCATGGTCACCTCTTTCGGTTGCTGGGGTTTTGCGGGGGGTGCGGGGAGTGCGGGGAGTCGATGCGGGGAGTGCACAGCTCCTTCCGAGCAGGTCTGATCAGGGGCTTTGCGGGGACGCGGGGACTTGCGGGGAGTTGAGAGATCCCTTGATGCCGGAGGGCCTCAGAACTGACCGGTGATGATGTGAGGCGCACATGTCGTGCGATGCATGTGCGACGTGCGCGCCATAGGGGAGGCGGCGGCGGGCCCCCGCAGGTCCCCGCGTCCCCGCGTCCTCGCAGGCCGAGCCGGGTGCGGGGAGTGCCGCGACTCCCCGCACGAGTCCCCGCAGGGTCCCCGCACTCCCCGCAATACGGCCGGTCACGATTCGTGCCGTCCGGTGCCTCGGTCGGCGTGGGCCTCGACGCGCCACAGGTTCTGCTTGCGGTGGCTGTCCACGACCAACACCGCCTTGTGCGTGCCGAAGTAGCGGCCCTGCCTGGCCTTCAGCCAGATGCCCAGCTGGTTCGCGCTCGGCGGCTCGTCGCCCTTGCGCGGCACGTGGTTGGGCAAGCCCTTGATGAGGGCGCCGGTGGCGAGGGGCTCGGCGCCATAGGTCTCCCGCCACATCTCCAGGAAGTACGCCCACTCCTGCGCCTCGTCGTCCTGGGTCTGGGCGTCGGCGCTGTCCGCCATCCAGCCCTCGACGCCGAGGAAGTCGAGCAGGCCGGCCATCATGGACGCCCACTCGCTGTAGTCCCCCTTGCGGACGCGGATGCGGGGCGCTCCGGCGGCGAGCCATGCCCGCACGAGGGTGACGAGCGCGGCGACCAGGGTGGAGGCGTTGGCGCGAAGCCACGGCCGGAGGTCGCCGATGCGGAAGCCGTCGCGCTGGTCGGGGTCGGGGCAGTCGGGGTCCAACTTCACCCAGAGGACGCGGCGGCGTTGGTCCCCTCCGGTCCGCAGCGCGTTGCCGGTGACGAGCCACAGCCGGTCGTTGCGCATGGTGACCTTGCCCGTGGCCCCGAGAATGCGGTCGCCCCAGTGCTCGCCGGTCAGCAGGGCCGACAGGAGCGGCGTCTTCAGGACGAAGCCGTTCGGCAGGTTGTCGAACGACACGACGGGGCTGCCGGTGCCGTAGAGCTGCGTGGTGATGCTCTTGCGCAGCTCGGTGTCGTTCTCGGGCCAGGCCGTGTCTGCCGTGCCGTAGCAGAACTTGAAGATGTCCTTGAGCAGGGTCTTGCCGCTGCCCGCCGCTGTCGCGGTGATGGCCACCATCTGGGTCGGACCGTGGAAGTACGCCCGCACGATCGGGGTGAGCAGGGCGCCGAGGAAGTTGGCTCGGTCGCTGGCCGCGACCCACGGGAAGTCAGCGAGGACCTGGCCCAGCACGATGTCCTTCGCCCGGTCCAGGCTGTCGCGGGTGACCTGTGGCTGGAGGCGGCGCAGGGGGACCCGCGGCTCCAGGTAGAGCCCGGTGCTCCGGTCGTACCCGGGGGCCTCCAGCAGGCTGCCGTCGGGCCGGATCACGGGCGAGGTGACGACGCCGCGCAGGACCGGCAGCGGCCAGTCCTTCCGGCCGAGGAGCGTGGCGCAGCTCTTGGGCATGAGCAGCTCGCGTTCCTCCTCCAGCTGCTCGGTGACCGGGTTCCGCTTCACGGTGAAGCTGGCGACGTGGTCGGCGAGGTAGGCCCGCAGGTTGTCCGTTCCCAGCTGCTGGACCACCGGGTCGTCGTTGTCGTCGCGGTACACCCAGCAGGGTCCGCCGGACCGCTTGTAGAGGTCGGGCAGGCGGCCGTCGGCCATGAGCGCCAGGACGCCATCGATGCCGTCCGCCTCGTTCGTGATGTCCAGCTCCGGGCGGGACGGCACGGAGCGCAGCTGCGGGCCGCCCTCGAACGCCCCCTCCTCCGGCGCGTGGTCGGGGTCGAGCGCGGACGAGCCGTCGGCGAAGTGCTGCTGTGCGGGGACGGAGGACAGGCGACGGCGGGGCGGCTCGCTGCCGTAGCCCTGGCGCCGCAGGTCGGCGGCGGCCGCCTTGAAGTTGCCGCCGTGGGTGAGCGCGGCGTAGGCGCCGAACTTGGTGTACGGGGTGTCGGCCTGGAGTTCCGAGCCGGTGGCGAACACCCAGAGCCGGTCGTGCTCGTCACGCCCGGTGGTCGCCTTCACCCCGCCGACGCCGTCGGCCCATCCCCAGTAGGTGGTGGACCCGCGGGTGATGAGGGGGCGGAACAGGCCGCGCAGGATCTCGTCCCAGGTGGCGCGGGCCTCGAAGTCCTCGCCGGGCCGGACGCCGCCCTCGGGCAGTGGCTGCTGCGGCCGGGGCGCGGTCTTCGGAGACTCGGGCTTCGGGAGGGTGTCGAGCATGCGGCAGACGTCGCGGACCGCCTGCCAGGTCTCCACGTCGAGGGTCGGGATGGTGGCGGGCCCGCCCTCCAGCCGCACGTACGGCTGGCCGGAGGCGTGCACTGCACCGCCGGACGGTTCCACCAGGCCGTACCCGCCTTGGCCGCGGGTCTCGATCTGGACGCGGATGATCCGCGCGCCCGGCTTCTCGCGGAGCCGCTGCTGCTCCTCGTCGGTGTACTCGTCTTCACGGGCCAGCCTGGAGGCGAGCTTGGTGTTGCCGGGCACGTCGGCGCCCTCGACGTGGACGCGGTAGTGCCGGCCGCCGGACGGGGACTCGGTGGCCCAGCCGGTGAGCACCTGGGCCCAGGGCTCGCCGAGCCCGGACGCCTCCATGATCTCCGTGGCCTCGTCCAGCAGGCCCTCGCGCACGGCGTGGCCCTCGAACTCGATCATCTCGACGTTGCCGGAGACGGCGCCGTAGACGACCGCGAGGCCCGCCGGTCGGCCGGAACCGAACCACGTGTCGTGCTCGGCCGGGGTGGACCGCTCCAGCTTGTACGGGGTCCAGGAGCGGACGGACGGGGCCTTGCTGCCGTCCGCCTTGATGGGGATGACGCACAGGCCAGCGTCGTGCAGCTCGCGGGCGGAAGCCCGGAGGTCGGTGGGCTGTGGGTCGGTCAACGGGTGCTCCCGTGGTACGTGGTGAGGTGGTGGTCTTTGACCCCGGCGACGAACGCGGCGACTCCGCCGGGGCCGCGCGGGATGAGGGCCCCGTTCGCGGCGCGGATGCGGTCGGTCGCGCACACCGGGCCCTCCAGGGGGTGCGGGCAGCCGGGGCGCGCGCACTCGTACTTGGCGCGCTGCCCGTCGAGGTCGACGGACAGGGCGGCGACGAAGGGGCGCGCGGTGGGGGTGCTCACTGGGGGCCCCCGTTCACGCGGGCCTGGAAGGCGGCGGCGCGGCGCGCGTCGTCCGCACACAGCTCGATCTCCTCGCGGAGCTGCTGGACGGTGTCCTCCGGGGGCTGGCCGGCGGGGCAAATGGCCATGCCGGTGCCGCCAGCGGTCCAGATCACGAAGGTGCGGTCCGACTGCACCGCGGCCCGGGACTCGTGCAGCGTGATGCGGTGGGCGGCGGCGAGGCGCAGCAGTTTCTCGCGAGGGGAAGACTCAGACACGGGGAGCCTCCTCCTTGCCGGGGGTGGGCTGCACGGGGAGGGCAGCGGCCGCCTGGACCTCGGCGGTGACGAGGTCGGCGAGCCCGAGGTAGGCGAGCAGCTCGACCTTGCGGACGCGGAACGCGCGGCCGAGGCGGACGACCTCGATCGGGAACTGGCCCTGCCTGATCAGCTCGTAGCCGAGCGTGCTGCCGACGTTCAGCGCGCTGAACGCCTGCTGGACCGTGGGCATCGCGGGCAGCTCGGCGACCTGCGCGGGCGTCAGGGGCGCGGCGGTCGTCATGCGACCACCTGCTGCTGCGCCGGGACGAAGACGCGACCGGCGCGCTCCATCGGGATGAAGAGGACCAGCAGGTCTACGCCGAGCCGGGAGGCGATGGCCTTGGCCTTGTGCTCGGGGATGACGCGTTGAGCGCCGGACATGAGCGCCCCGATGGTGCCGTGGGAGACGCCGACGGCCTCGGCGAGGCCCCTGCTGGTGATGGGCTCGCCGGTGCCGGTGCGCTCCATCAGGAGCTTGAGGCGGTCGCCGCTGACGACCGCGTACATGGGTACTTCCAGGGGTCCGGACATACGTCGTTCACCTCGCGGGACGGTTCATTCATCGCACTGAATGGCGATGGGGAGAGCATCACACGAGCTGAACGCAATGTCCAGCGAGCTGAATATGGACGGTGGTTGCGCCGAGATCCGGACATTGACCTGTGGCGGACTGGCGAAGTTGGCTACCGTGCTGAACAATCCGTCCAGTCAGCGGAATGGGTGCGCCGACTGACCTGCACATACGTTCCAGCAGCCCCACGCGTACACCTGAACGACGTGCAGTTCCCCGAGCCCCAGGAGTGACAGGATGAGGTTCATGTCGGCGAGCAACGAAGAGACCAGAGACCAGGGCGGTCACCCTGAACGGCGCCAGTTTGCGGACTTGGTGCGGCGGCGCCGGGCAGAGCTGAACGAGAGCCTCGACACCTTCGCGCGGCGGGCCGTGGACCCCATCTCCGGCGAGCGGATCACCCGTGGCTGGATCTACCGCCTGGAGACGGGCGAGCCCGTGACGCCCCCGGCGATCGCGCAACTGCGCGCGCTGGCGGCTGCGTGCCAGCTCCCCCTGGGGCAGTTGCAGGACGCGGCCGGCCAGCAGTTCCACGGCGTCGACCCGCTGGTCAGCGGATCAGCCGAGGCGACCGCCTACGTGCGCAAACTCGACCGGCTCCCCGCCGACCAGCGCGAGCGCCTGCTGCGCCTGATCGACACCCTCGTACCACCCGAGGAGGCGTGAGTCCCCATTCCCCTTAGCGTCACTGACTGTGATCATTAAGAGCTTTCAGTAGAGATTTGCGACCCGTGGTGCGATCATGTGCGCACGCCGAGGACCGCAACGGTGCTGGTCCGCTCGGGGATTCGAACGCATGCACGATTCGGCATGCTTGGCATGGGGGAGGTTGCATGGAGTCACAACGTGCGCGGGTCGAGTACGTATTCAGCGATGACCTGCCGGACGGGGAGGTGATCGTCCCGGTAAGGACAAAGGCGGGGGCGTGGATCTTCCCGGTGCGACGAGGGGAGATGACCCAGCGCATGCTCGACGGGCTCAACGCGGTCGCGGCCCACATCGTCGGGGTCGGGCTGGTCCAGATCAGCGACAATGAGAAGCCGCCTGAAGGCGACCAGAAGGAGTGACCAGATGCCGTCAGCACGCCGGGCCGGGAGCGTCTACCGCCGGTGCGAGTGCCGCGACGGCGACGGCAAGCTGCTGAGCGCCAAGTGCCCTCGGCTCAAGAAGAAGAACCACGGGTCCGTCGGGCTCCGCCAGGAGCTGCCGCCGGACGCCGAGGGGAAGCGCCGGACCTTCCGGCGTACCGGATACACCGAGGTGAACAAGGCCCAGGGCGACCTCTCCCGCCTACAGGCCATCCTCGAACTCGCCGGCGACGACGAGGCGGACCAGCTCCGCGTCGGCGACCTTCTCGCAGACATCAATCGACGTCGCGCTGACATCCCCCAGGTGGACGAAGTCAAGCGGCGCCTCGGCGTGGGCGTTCCGCTGGATGGCGCGACCACCGTCGGTGAGTGGCTCGACCGGTGGATGGCTGGCAAGAAGACCAGGGCCACCACGAACGCGGGCTACTCCTCGCACATCAAGGTCCACCTGCGGCCCCGCATCGGCCACTACCGCCTCGACCGCCTGAACGTCGGCCACGTCCAGGCCATGTTCGACGCCATCGCCGACGAGTCCGACACCATCCGGGCCGAGAACGCGGCACGCCGCGAGCAGGAAGCGCGGGCGAAGTGGACGCGCCCCGGCCGCCCGCCGACCGCCGAGCGCGAGCGCCTGGCCGCCGAGCGCGCCAAGCTCGCCCAGATGAAGCCGTACCGGAAGGCCAACGGGCCTGCGACGCGGCACGCGATTCGGCGCACACTCCGTACGGCGCTGAACTCGGCCATCGCACAACAGCTCATCACCTTCAACGCGGCTGCGCACGTGGAGCTGGGGCCCAACGCGCGCCCCAAGGGTCTGCTCTGGACCGCCGAACGGGTCGCCCGGTGGCGCCTCACCGGCGAGAAGCCGAGCCCCGTGATGGTGTGGACACCCGAGCAGCTAGGCCACTTCCTCGACACTGCCGAGTCCAACAGCCGCCTCTACCCGTGCTACCACGTGATCGCCCACCACGGCCTGCGACGAGGCGAAGGGGTCGGCGCGGACTGGGACAACGCCCACCTGGACGGCCCGGGGCCCGCGCGTATCGACGTGCTCACGGAGATCGTGGTGGACGGTTGGGAACCCGTGGAGACCGTGCCCAAGACGGACAGCAGCATGTCCTCGGTGATGCTCGACCGTGGCACGGTCGAGGTCCTGCGCGCGCACCGAGTACGGCAGCTCGCAGAACGGGACGACCGGTTGTCGAGGGGGCTGCCGTGGACGGACACGGGCAAGATGTTCACCCGTCCCGACGGCACTTGGCTCCACCCCGATGAAGTGAGCCGAGAGTTCCTCCGCATCGTGGACCTCGCCGGCCTGCCGCCGATCAACCTGCGCGACCTCCGGCATGGCGCGGCCGGACTCGTGAAGGCCGGGGGCGGAGACATCCATGACGCCAAGGTGAAGCTGCGACACTCCACCATCGTGCTCACCGCGGACACCTACATGAGCTTGTTCGAGGAGTACGAGGACGAGCTGACGGAACGGGCAGCGGCGGCAGTGCCCCGGGCGGCCCGCCGCGATGCTGGGAATGGCGAAGCCCCTGCCGCAGATGTTCCGCAGCAGGGGCCGGGCGTGCCGCAGCCAGCAGACACTTTTGTGGACGTCTACACCGTAGGGGCCTGCACTGACACTGACGGTGCGGAAGCGTAG

Protein sequences of DBSCAN-SWA_1

>NZ_CP047147|3775404:3810036|3786572_3787115_-|WP_159312707.1|DBSCAN-SWA
MALVTLAEARAHLDIDTERHDTELGLYVEALTSVIEGYVGAVEPRQVTQEVTAHRGALILLTTPVLSVTLAEPYDGGPGLDTATLSVDAAGVVRRRDGAPVPAGAWTVAYTVGRADVPPTIRLAALMLLQHLWRTQNGAARGMGGADDFAVTEPIPGFGYAVPNRVLQLLEPFKLPPGVA
>NZ_CP047147|3775404:3810036|3806676_3806967_-|WP_159312734.1|DBSCAN-SWA
MTTAAPLTPAQVAELPAMPTVQQAFSALNVGSTLGYELIRQGQFPIEVVRLGRAFRVRKVELLAYLGLADLVTAEVQAAAALPVQPTPGKEEAPRV
>NZ_CP047147|3775404:3810036|3786099_3786573_-|WP_159312706.1|DBSCAN-SWA
MEATSRVPAAVDALLALLRGSPALELVHIQDGPPSTKQSADRHRLYIGWSPGADQAVDLQQNFAVAGARRRDEAFSISCYAESRAGDKDMALRRARVFEIVATVEAVLRASDAAPAAPTLGGTVLWSELTAGALDQVQDSEGSLAGLAFTVSCRARI
>NZ_CP047147|3775404:3810036|3787346_3787736_-|WP_159312709.1|DBSCAN-SWA
MATTPKKDAGASGVLQDQPTPTAAERGDHDRIVMASRRADGSMDQVDPEFIGDKDVALAAAKEQLAVQATSAVDVAARGVTAGQGAGGAESADPDPDIKALKDAQEKAAEAAEARAEAEVTDRHQGLGD
>NZ_CP047147|3775404:3810036|3795004_3795763_-|WP_159312719.1|DBSCAN-SWA
MSAADRLRPAADRLARGAGRLGPALARRATAWARRGHRDDLTGLAAHLGTLLRAALIALGLYLVARAVRATPSLMWVVAGVALLAAWRAGRPAPAKDDKKEAAEKTDEPPAEMPEEVAEEVPAEAAEEAPAEAPLPTREELALALRAVADPNAHTAALAAHMQLPADRVRAALKAARIPAGGQVRMGGVTSTGIKASNFPPLPPAESGDPTPVVVAGQDSNSSSSDAPRVVRGEGTVTIYDPAETHRHHKVA
>NZ_CP047147|3775404:3810036|3791158_3791338_-|WP_159312713.1|DBSCAN-SWA
MVTTLLYVLEFLAVAAALAGVALVYVPAALILGGVLGVVVAERALASGPPAPRRKGAGQ
>NZ_CP047147|3775404:3810036|3796804_3798178_-|WP_159312722.1|DBSCAN-SWA
MTEMLLRWAGANPWPTAAITLVVALALALLLRAAVRRLRGLDWPPGFVLVFGAAAALCTLYSGDTSWRFAESHLGMDRFAERAVMFAAGEVALLACAIGARARKRATAGDEGTGSAGVPGALVWLITAVQIVPAYAESGWWGGTVRAFFGPVMAGLLWHLAMGLEVRVRRPEALTGGLAATLGRELRARLLSRLGLAARERTAEQITRDRWTARAVDLAAQLALRQGRGTAWRRARLERRLDRAVGRAQVGASRAQRDALLGALATRLHSRALPTLQLASPWDPPRDPVRPVQRPEAAAARELRAMDPLDATLVVAGAHPAVTVDELRALLGDLGIVVSNTQVELALRAGASGARPAPGCAPAAGQTRTTVHARIPDPSDPDAAGGDPATPDADAPDADAPDADADRALLPDARRLDAQHRRDHGRPAPLRALQSGLRIGQARAQRMRALLDAEVQP
>NZ_CP047147|3775404:3810036|3799970_3801050_-|WP_159312728.1|DBSCAN-SWA
MIVDLFSGPRGWSEGLRMLGLTDIGLELDTAACRTAVAAGHPTIQCDIATYPTAPVAGRITGLIASPPCQAWSRAGKRGGLADQPLVHQAVHDLAHGRDTRAQLLARCRDPRSLLAAEPMRWLTDLQPEWVCMEEVVDVLPLWQQYAGILRGRGYSVWAGVLNAADYGVPQTRRRAILIASRTRAVTAPGPTHSEQAMTPGLFGPGRARWVSMAEALGWPDGQTVVTRGERRTPGGNAFLADGPSWALTEKTRSWVLRSGQSVAGEGRAERRADQPAVTMTSRADLCAWVPSDQPADTVRITVAEAAALQTFPVDHPWQGTRTKQFEQIGNAVPPLLAAHIVAAATGLPAPALPKEFAR
>NZ_CP047147|3775404:3810036|3798764_3799382_-|WP_159312725.1|DBSCAN-SWA
MTTCDLCNRATSGYLCTRHGEELAARLRALPALYAEVGEFLVPRRSGWGDIVATKAPAGPRSPINEDVLDTVTWARATNAIHARRAEVRRLRWPHRGSAPHPDLARDCQWLAQEVDWVVAQYPAAGDLAREVAELTSQARSVVGDPEPRRQRLGYCVALVGGEGVCGAVITRLPDETRLTCRWCGTTYGPEDYLTLRHFQPAGTP
>NZ_CP047147|3775404:3810036|3787128_3787347_-|WP_159312708.1|DBSCAN-SWA
MARIRMLTSVAGAGFSWRAGEEIDLPGAEAAKWADGVRAELVRTSPVETPETPPAETTARRTRRKQPAPGGE
>NZ_CP047147|3775404:3810036|3799378_3799645_-|WP_159312726.1|DBSCAN-SWA
MSQRRYTANDITDDALDELYTNANEGWRRGDRWKERALRAEAAVSRLTGWCDDLDEYMQVVVKDTTSKHPIAETVRQHLAEPEETSTK
>NZ_CP047147|3775404:3810036|3794773_3794929_-|WP_159312718.1|DBSCAN-SWA
MGLFRKSMPLSEFTQSDEDKKKFETTYQASRGGWVKPTEKPVPGKRKKDRR
>NZ_CP047147|3775404:3810036|3784365_3784875_-|WP_159312703.1|DBSCAN-SWA
MRVQILGTGQLLELQRRLRAAGNENIRASMQRRVRRAAEPLQGALQDSIRHLDLTSAGRKPGKRGGQSPTTRPLRATIAGAIRISVRNTGAGAGARVWIDIDRLPNDITFGLLKQINEGKVRHPVFGNKSRWAQQNASPLWWDRTVRAHTPRMTREVERVVDDVRRRLN
>NZ_CP047147|3775404:3810036|3789827_3791162_-|WP_159312712.1|portal|DBSCAN-SWA
MSLFGLFERRASVENPKVPLTSESLLSLLGGSAGASGVAVTETSSLRMPAVWRAVSVIANVSAALPLHTYAAGTKDRATVALLEDPHPELTRFELWRLLYVHRLLWGNAYAQKIRNGAGDIVQLWPIRPDRVKVDREPATEDNPGGKVFWVKDDQGRRVRLTSREILHLPALGYDGVTGCSPVRAAAEGIGLGIAAEKAAAELYGSGNMISGILQTEQRLTREQAASLKAAWNAKLSGGSALDIGVLDSGASFQPVTMPYRDSQFLESRQFQVTEVSRMFGVPPFLLMSTEKSTSWGTGLEQQAQGFVTWDLAPTWLTPTEQRVTKELLDPTRQYAKYQLGGLLRGDSSARATFYRAMRDTGAFSADDIRDLEDLTPLGGREGNMRLQPMYMAPLGSDPTATAPAADGEPDDRAARAARHLAAAHRLLNPPTPPEEGGDDEPQH
>NZ_CP047147|3775404:3810036|3795759_3796263_-|WP_159312720.1|DBSCAN-SWA
MTTSITLAGLAVGLLVAWANLRPWWRGGRAPKDLLPFSEGFVLGAMSTVCAGLLGWAASGLAGGATAGGDKVTAGLTGAGAGTPIPRGSMGTLTPEGAVMVVLLTAGVGLAWKLAPKADKRRIFGGVFVGVVLCATAGIASALDWLPETFNIAGDYLRSAASGAGIL
>NZ_CP047147|3775404:3810036|3780026_3783752_-|WP_159313923.1|DBSCAN-SWA
MTFVLAGRDQLSRVLRGVETSAGRLERRLVAAATVSSSAMDRLSRNTARRMADMERDADAGGRAIEALKGSLISLAPAAIPAAAAAAGALAPIVAGTGAAAVAAGAYALALGPQVSAMTEASEAEKKYADAVAKSGRASQEAVQAEEEYHRLLADMPPATRRAAAGLGVLKDEYADWSDDLAKDTLAPFNKGLAITSGLLPKTSGLVRGTSSELDRMMTIAAGAMNTPGFDKAVGRFEKFATGTLAKVNRGLVDLYAGRGDAGKIAPGAREFMEYAQAQGPLVADTLANIGRAVINVLRAGSEVGVSALEIVNAISGIVAAAPPEAITMLLQLAIAVKAVNLAAAGGAAARTALAGLGAQLVAMQTAAGGVPGRLAAARAAIAALSRTAKMALAGTGIGLLLIGLGKLNSMAQTTPPNVDKLATSFKNLAASGKESGELKRVFGGLDGIGKAARQVRGDMAELDSVRDWAGLVGLGKAADGVVLKLDSLIRGDSSFNAAKEKLASVDKALAQMATSGHAAEAASGFEAVSQAMRDNGASTKDIAAAFPEYKAALASAKVEQQLAAQAMGVFGTQAQQVQAKLDTQKRSADGLAQSINALSNQYLQARGGIRGMEAAIDAATAAIKKNGRTLDEGTEKGRANNQALDDLASATMKAAESARQGGQSWSQVNAIYARGRGELVKSAQAMGLTEAQARKLAGQILKTPNKTAQLKGNMEDLQAKLASAKSKLASVPDSRKAAVRAQISDLQAKVRQAKADLASLRDRSVTVTTRYVTVGDGSAARKSGSYGAQLKAAGGRVGGPGGYVEGPGSGTSDSILTRLSNGEFVVRARSVARYGLAFLNAINEGRLGMSAMSSGGAMGGAGRETARGLAVGMTGAAGTVEAAARVMASAVEAGVRAELQIASPSKKTKTLAKHAGKGFIDGLTGSRDKIKATAKAISKDIYAAFTGSKDDKLVAKIKKGTTKLLAAAKERDKIAATIKRAKDFAESSRVTAKKAASLGAMFDSEETVSAGNIRKKLKAKLAKIKQFSAFVKTLAKRGLNKTMLREIMEMGPEDGYAYASALAGADKATFKEINKTQYAINAEAEKLGKRGADALYDSGKNAGKGFLKGLESQQKAIEKQMEKIAKGMQKAIRKALGIKSPSRVLAEIGRYSSEGLAVGLTEGRPAVDRAMVGVAGAVSGVQPVIGRPVTHGSGAVGGQPVSIQIDVHGAMDPVAVGREIQRTLLHLKRSHGVNVNLGVG
>NZ_CP047147|3775404:3810036|3776560_3777091_-|WP_159312699.1|DBSCAN-SWA
MTFAPRTWFPGEIVTEGLLNEQIRDQFASFLGAWTEYTPTWIAETGGTPSVGNGSLTGRYLKVGRTVNFLIKLSVGSTTTFGAANANWAFGLPASPSSVFHGARCLTVSARIAGVGEVTGTGETSTSNGGTARAFAGGSVNGTTNQPDSSYWDQTNPLAAAAGMSFHVSGCYEASS
>NZ_CP047147|3775404:3810036|3807609_3807963_+|WP_159312736.1|DBSCAN-SWA
MVRRRRAELNESLDTFARRAVDPISGERITRGWIYRLETGEPVTPPAIAQLRALAAACQLPLGQLQDAAGQQFHGVDPLVSGSAEATAYVRKLDRLPADQRERLLRLIDTLVPPEEA
>NZ_CP047147|3775404:3810036|3801571_3803182_-|WP_159312730.1|DBSCAN-SWA
MTTFTPRPYQVDAIEALRSGWAAGTNRLAVVLPTGAGKTVVFSHLAHQMLDTLGGHRVLVIAHREELIEQAAAKLLAVDPMLRVGIVKAERDQHQDADVIVASVQTLAVPRRREAIRDIGLVIVDECHHAAARTYMEVLEHFGAWRGVPVAGFTATMTRTDGGLAEVWQDVVFTLDILDMISDGYLCDVRGKRLTVDTLDLDTVRTRGGDLVDGQLGKALEDSGALEAIAQAYTQHAADRPGVVFTPTVATAQAAADALRAAGVTAAPVWGDMGREERRATLARYSAGDVQVLTNCMVLTEGFDAPHTSCAVIARPTKSPGLYVQMAGRALRPAPGKTDALLLDVIGASTRHKLASMVDLTAREVGEAEEGKSLREIADEAAVIEKRRTLAARVAAEEINLFGESAIRWLRTPSGVWFIRLTSAMFLFLQRDPGTRLYRMRRWTQAGGVQAPKDDVARPLPDALAWLEQQAKTLAPRAFVARQARWRSAPPSPAQLGLCRRLGIAVPRGASAGDVADLIDQDRVNGVLGQLILPAA
>NZ_CP047147|3775404:3810036|3789094_3789844_-|WP_159312711.1|head,protease|DBSCAN-SWA
MNRSTEERRDLALATAGVQLRAADDGQGARSFAGHAAVFGQRTAIGNPLTWGFYEEIAPGAFTKTLTEGDARFLVDHDTRLVVSRVSAGSLRLAQDAQGLAVDADLDTRLTYVNDLVVNLDLRNITGMSFGFRTVKDDWETVSVQTSEGDMEAELRVIREVQLFEVSAVTFPAYEGTDAALRSVGVALAARGNADAFDRRAALRPELLDFRPEPAESTRGHDAPQPGETTGSRQARQMDLLAARYRLAR
>NZ_CP047147|3775404:3810036|3775634_3776492_-|WP_159312698.1|DBSCAN-SWA
MAPPMSADRFIKALRDEGLSVVEVGSWRTHNRNSKGAWGPVNGVMIHHTVTSGSATSVRICRDGHSQLPGPLCHGVITKDGRVHLVGYGRTNHAGAGDGDVLAAVIAERALPKPNEANTDGNARFYGFECENLGDGKDPWPAAQLDAIERVSAAICRVHGWDAASVIGHLEWQPGKIDPRGFTMASMRTRVAKRLSVPAGKTPTPTTPDKEAPVNAKELHEAVWKRDAIPAPSTAKTAKTNPTWKAESFLPETYDQTNRILDVVRQLAKDVAALRAEVAALKKGA
>NZ_CP047147|3775404:3810036|3791331_3792792_-|WP_159313925.1|terminase|DBSCAN-SWA
MYGWQTPPIQTAPSAASSAGQEAIDLAARAGLHLDPWQQHVLRVGMGEKPDGSWAAFEVAVNVPRQNGKGGIIEARELWGLFIGGEQLILHSAHEFKTAKAAFKRVERLIRQTPDLHKRVKAYRYTVGEESIELHTGQTLRFIARSKGSGRGFTGDCNILDEDMILGDDAMDALLPTMAAVDNPQIWYLGSAGIGAPSVQLGRLRRRALAALEAGAPDPSLAYFEWSADLHAAECPSDCTAHDDPASDEAVLKANPALGYRLTLDKVANERATLSRDGYARERLGVGLYPSDEADTWQVIGEDAWRSLAAAESAPENPVVFSIDVTPERSHAAICVAGPWRGGTHVEVVEHRPGTGWVVERAKELHAKWGPRCWVVDGAGPAGSLIADLEDEETGLGVTVVQPKARDVAAACGQFYDAVADQTLSHLDNAPLATALAGAQKRPLGDAWAWARRGVDTDISPLVAATLAKWGLGAEVEEEKGVPNLW
>NZ_CP047147|3775404:3810036|3785872_3786079_-|WP_159312705.1|DBSCAN-SWA
MARVRFIGREPVTVPELGGRSVEPDEVVEVPDARFEGYVCQPGTWESVEEPGHAPAKKAAAAKSQKES
>NZ_CP047147|3775404:3810036|3794050_3794314_-|WP_159312716.1|DBSCAN-SWA
MRIRTTVLAALTAGLLLTGCGKSYDQSVKDCRAALSVEHTVTNRPAACNDLKEEDYKLILAHYVTEQAGGFDPFSPSPDADEPLWDE
>NZ_CP047147|3775404:3810036|3775404_3775632_-|WP_159312697.1|holin|DBSCAN-SWA
MAASSAPIETKVKASSVATYLLSLAALAILGAVTDDPSLIAGMPDALEPFVLALVPAAASAVAGWAAPHTPRPDA
>NZ_CP047147|3775404:3810036|3796259_3796808_-|WP_159312721.1|DBSCAN-SWA
MTDNPQPITPSQIIPAGQPLPPRPPDPNDPPWHQRKAPVPPAPWAPGPAAPADPPPPIQVYVTVDLTPGEEPPPSTRTQRAVDWLWDRCTDWKLLSAVLAALAPWLNGTSPVGAWAATLHDARTEAGLPAAYLIAAVALAAAWAINRRGRWLGRFAFTTALLGATGVLDLYDLVLLLTGVPR
>NZ_CP047147|3775404:3810036|3808368_3810036_+|WP_159312738.1|integrase|DBSCAN-SWA
MPSARRAGSVYRRCECRDGDGKLLSAKCPRLKKKNHGSVGLRQELPPDAEGKRRTFRRTGYTEVNKAQGDLSRLQAILELAGDDEADQLRVGDLLADINRRRADIPQVDEVKRRLGVGVPLDGATTVGEWLDRWMAGKKTRATTNAGYSSHIKVHLRPRIGHYRLDRLNVGHVQAMFDAIADESDTIRAENAARREQEARAKWTRPGRPPTAERERLAAERAKLAQMKPYRKANGPATRHAIRRTLRTALNSAIAQQLITFNAAAHVELGPNARPKGLLWTAERVARWRLTGEKPSPVMVWTPEQLGHFLDTAESNSRLYPCYHVIAHHGLRRGEGVGADWDNAHLDGPGPARIDVLTEIVVDGWEPVETVPKTDSSMSSVMLDRGTVEVLRAHRVRQLAERDDRLSRGLPWTDTGKMFTRPDGTWLHPDEVSREFLRIVDLAGLPPINLRDLRHGAAGLVKAGGGDIHDAKVKLRHSTIVLTADTYMSLFEEYEDELTERAAAAVPRAARRDAGNGEAPAADVPQQGPGVPQPADTFVDVYTVGACTDTDGAEA
>NZ_CP047147|3775404:3810036|3792799_3793075_-|WP_159313924.1|DBSCAN-SWA
MMGAVTDAVNAEIHQLGVEPVSPGLSELATSLAQSVDEAEAPTARAVAARELRAVMADLRRLAPVAAKGDAVDDIAEQRAKRRAAARAAGD
>NZ_CP047147|3775404:3810036|3806963_3807257_-|WP_159312735.1|DBSCAN-SWA
MSGPLEVPMYAVVSGDRLKLLMERTGTGEPITSRGLAEAVGVSHGTIGALMSGAQRVIPEHKAKAIASRLGVDLLVLFIPMERAGRVFVPAQQQVVA
>NZ_CP047147|3775404:3810036|3793318_3793756_-|WP_159312714.1|DBSCAN-SWA
MLYVVTGPPAAGKSTWIEARAKARDVVIDLDRITRALTGPGAPQWNHDRVAVRVALRARYAAIDEALSHLDTVDVYLIHTMPSPKHLAKYKRLKAKVIAVDPGEEIVMQRIDTMRDPAMRRVAARWYNARRNRPREAMPQASRRW
>NZ_CP047147|3775404:3810036|3799641_3799974_-|WP_159312727.1|DBSCAN-SWA
MTRPRLLRAGYFLGGAWVTYCAVVSAQAGAPATAAAFVVVLGLLLVAAIREAELTYVRAVAADLRLALRVHTTRAARRADYAALDGACCLPGWESRGATHSNTCTGRTPA
>NZ_CP047147|3775404:3810036|3801046_3801244_-|WP_159312729.1|DBSCAN-SWA
MNAPLAWLGLALLLTISAPALIGRRYPRITPVDSEPCDRCTGGPGCRCADGWTNPDTCECLEATR
>NZ_CP047147|3775404:3810036|3784884_3785871_-|WP_159312704.1|DBSCAN-SWA
MAIGSGLGAQVGIAAESVYGTAVPPTKFIEFTKEGLQLKKTTAQSAGIAAGRLVPLASRRVVTQREASGSLEMEVTNKGMGVLLQSLMGTTVTPTQQASTDAYLQTHILADVFGKSLTIQKGVPLTTGVVTDKTFTGCKIVSAEFSCEVGGMLTASFEIDSKDCDETQTLAVATYPAMSPFHFGQMGVKTGAYGSETVRQGIRKVSVKIERPLATDRFYANSSALKAEPISNDQVKVTGSLEGDYVDTILDDLHTSDAGVSLVWDFTGPLIAATHYERFTVKLPVIKLDDAPPTVEGFDLVKPTFNFTALSDGTNPIAVEYMSTDETL
>NZ_CP047147|3775404:3810036|3806184_3806427_-|WP_159312732.1|DBSCAN-SWA
MSTPTARPFVAALSVDLDGQRAKYECARPGCPHPLEGPVCATDRIRAANGALIPRGPGGVAAFVAGVKDHHLTTYHGSTR
>NZ_CP047147|3775404:3810036|3787777_3789028_-|WP_159312710.1|capsid|DBSCAN-SWA
MANLQSLLDQRASAWDKAQEFQNRSASETDMSAEDRSAWDAALADVERLSTDIEREERHQRLAAVDYTQVIQAAKEEDDERHGGPDQAAAYADAWRTWMRDGATELSGEERGALRTGWVDGKELRAQGVATGAAGGYLVPPAFRAKLAEAQKFLSSMRDSAEVITTETGATLPWPTADDTANVGAILAENTQVTEQDVTFGQADIGAYTYTSKLVRVSLQLLNDNAFDAESWLARKLGERIGRAQNAHFTTGTGTNQPEGVQTNAGIGKTGAAGQTTSVTYDDLIDLIHSVDPAYRLGGRAGWMLHDTTLATARKLKDGQGRPLWEPSVQVGVPDALLGYKYTVNQDMPAMAANARSILFGDLYAGYLIRDVQDVQLLRLSERYADFLQVGFLAFARADGTPQDTAAYKAYRNAAT
>NZ_CP047147|3775404:3810036|3803539_3806188_-|WP_159312731.1|DBSCAN-SWA
MTDPQPTDLRASARELHDAGLCVIPIKADGSKAPSVRSWTPYKLERSTPAEHDTWFGSGRPAGLAVVYGAVSGNVEMIEFEGHAVREGLLDEATEIMEASGLGEPWAQVLTGWATESPSGGRHYRVHVEGADVPGNTKLASRLAREDEYTDEEQQRLREKPGARIIRVQIETRGQGGYGLVEPSGGAVHASGQPYVRLEGGPATIPTLDVETWQAVRDVCRMLDTLPKPESPKTAPRPQQPLPEGGVRPGEDFEARATWDEILRGLFRPLITRGSTTYWGWADGVGGVKATTGRDEHDRLWVFATGSELQADTPYTKFGAYAALTHGGNFKAAAADLRRQGYGSEPPRRRLSSVPAQQHFADGSSALDPDHAPEEGAFEGGPQLRSVPSRPELDITNEADGIDGVLALMADGRLPDLYKRSGGPCWVYRDDNDDPVVQQLGTDNLRAYLADHVASFTVKRNPVTEQLEEERELLMPKSCATLLGRKDWPLPVLRGVVTSPVIRPDGSLLEAPGYDRSTGLYLEPRVPLRRLQPQVTRDSLDRAKDIVLGQVLADFPWVAASDRANFLGALLTPIVRAYFHGPTQMVAITATAAGSGKTLLKDIFKFCYGTADTAWPENDTELRKSITTQLYGTGSPVVSFDNLPNGFVLKTPLLSALLTGEHWGDRILGATGKVTMRNDRLWLVTGNALRTGGDQRRRVLWVKLDPDCPDPDQRDGFRIGDLRPWLRANASTLVAALVTLVRAWLAAGAPRIRVRKGDYSEWASMMAGLLDFLGVEGWMADSADAQTQDDEAQEWAYFLEMWRETYGAEPLATGALIKGLPNHVPRKGDEPPSANQLGIWLKARQGRYFGTHKAVLVVDSHRKQNLWRVEAHADRGTGRHES
>NZ_CP047147|3775404:3810036|3777576_3780024_-|WP_159312701.1|DBSCAN-SWA
MALLVEVGWGGVVQYPWSITWTDISRRVSMTEGISITRGAADERSETQPGSCTMTLDNQDGALTPGNAASPFHPFVRRNAPVRVAVAIIPTRTGAGPTWPLGQLGDDFDDDRIGTALWPSVYGGSTETGGRARVPLASGVVAGFQSARVWRLNGSQLSAKLARVPAANGSSSASASMWVLSTTAGTRLGFSYSPVTGQLRLASETAYFDGAAVSLPYSPIDHAWLRVRESAGTLRWETSRDGFIWTTRRTLATPAWVTSQTVLVDFSATRTGGATDYVEWDLVNATVRPRFWGMVNEFPVDWQGLHSSVTISATDLFKRLNRLPELRPMLTEEVSTSGALAYYPLTEASGNSAGDISGRGQPPLVRAQVGSGGTLAMAAVDGPPATGEQAPLATPVSATAGKYWVANLGADVANAISTYYFAAEAWFKGTEVTRAILGMSSWNYDQQIVIGVSSIGGLMIEWTDWIGGSLIAEGISGTTGILDDQWHHLVYDRGSNRFWLDGVMVDSTIDVPHMYDLRRLHVGGYRSSRLWSGSIAHVGIYAPTDSTWGANLATHYGAGATGHEGETADARITRLAKYAGLSSVSIWGDLHDPVAGQGAGGQPALARMREVEKTESARLWAERDWYGLAYQSRGIRYNPSPASDVVVLDYADLETSRVQLADDDQKLVNIVDAARPGGATQRVTAPESVLAFGQYEESLDILKTTDSGALAAAYWMVSRYGNPLPELREVPVEAYTHPRYLDILDAEIGSAITVTGLPAQAPAASMRVMVEGYVENIRSHSHLIQFHTSAAATDSVWKLADPDYSRLGITTRIAY
>NZ_CP047147|3775404:3810036|3794492_3794684_-|WP_159312717.1|DBSCAN-SWA
MHQQPLLVDAYAAQAATGIRPGTIRQWLRRGHLTHHGHDARGRVLIDLHELRARLALRSAAAA
>NZ_CP047147|3775404:3810036|3798174_3798453_-|WP_159312723.1|DBSCAN-SWA
MTTDQLDTIRLDAVALVTRLALRLRTERPTEPMRDGTRLALLLRFSEARCGYGTARAEHAERAARDLAPRVDRDITRGEYALLLDQVIGGAR
>NZ_CP047147|3775404:3810036|3777087_3777567_-|WP_159312700.1|DBSCAN-SWA
MAQPPVVHAETLYLPPAPTRKGQEREDWSQVPGAELVYLWMAANLGRRTPVPTDTVPGDPGTYARVDDNRWMADCANCGTGLVVSTDDPRFGCTQCGRDWVPLIVPSPEDVAAIDADLGEIEGRRFWWAEGDPRNPVQPEPPIPPRDPSWPDPSQEAVR
>NZ_CP047147|3775404:3810036|3793759_3794035_-|WP_159312715.1|DBSCAN-SWA
MPANPRNGRPYRRLVAALKRRGDPCWLCGRAIPHGLDARHPLSFTLDHVVPLSRGGQLLDPANARAAHRRCNSSRGNRMTPRPPARASRRW
>NZ_CP047147|3775404:3810036|3798449_3798608_-|WP_159312724.1|DBSCAN-SWA
MTDHFARPVAPASPPPRRLVAAGIITRRAGRTVTTICTPDGGRSTVTNGGAR
>NZ_CP047147|3775404:3810036|3783912_3784356_-|WP_159312702.1|DBSCAN-SWA
MLVSYRHEDGTVESVSTDDLSALESAEVEKVTGETWDGVESALRAESPTAMRAVLWVHRKRSAGNLRFTEFDLPSWRRRLTARLELADLEEMVGNLRRSGEAGGAGWDEVLEHLRSLADDPEDVDRAVAATSPKAAAPAKKPAASKS
>NZ_CP047147|3775404:3810036|3808130_3808364_+|WP_159312737.1|DBSCAN-SWA
MESQRARVEYVFSDDLPDGEVIVPVRTKAGAWIFPVRRGEMTQRMLDGLNAVAAHIVGVGLVQISDNEKPPEGDQKE
>NZ_CP047147|3775404:3810036|3806423_3806684_-|WP_159312733.1|DBSCAN-SWA
MSESSPREKLLRLAAAHRITLHESRAAVQSDRTFVIWTAGGTGMAICPAGQPPEDTVQQLREEIELCADDARRAAAFQARVNGGPQ

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_159312697.1|3775404_3775632_-|holin	holin	NA	NA	NA	NA
WP_159312698.1|3775634_3776492_-	N-acetylmuramoyl-L-alanine amidase	A0A1J0MCN5	Streptomyces_phage	1.6e-81	70.2
WP_159312699.1|3776560_3777091_-	hypothetical protein	A0A2H5BQA0	Pseudomonas_phage	1.2e-07	35.3
WP_159312700.1|3777087_3777567_-	hypothetical protein	NA	NA	NA	NA
WP_159312701.1|3777576_3780024_-	hypothetical protein	NA	NA	NA	NA
WP_159313923.1|3780026_3783752_-	hypothetical protein	A0A0S2MU35	Streptomyces_phage	2.7e-16	36.2
WP_159312702.1|3783912_3784356_-	hypothetical protein	NA	NA	NA	NA
WP_159312703.1|3784365_3784875_-	hypothetical protein	NA	NA	NA	NA
WP_159312704.1|3784884_3785871_-	hypothetical protein	NA	NA	NA	NA
WP_159312705.1|3785872_3786079_-	hypothetical protein	NA	NA	NA	NA
WP_159312706.1|3786099_3786573_-	hypothetical protein	NA	NA	NA	NA
WP_159312707.1|3786572_3787115_-	hypothetical protein	NA	NA	NA	NA
WP_159312708.1|3787128_3787347_-	hypothetical protein	NA	NA	NA	NA
WP_159312709.1|3787346_3787736_-	hypothetical protein	NA	NA	NA	NA
WP_159312710.1|3787777_3789028_-|capsid	phage major capsid protein	A0A0F7L2V9	uncultured_marine_virus	2.3e-68	39.2
WP_159312711.1|3789094_3789844_-|head,protease	HK97 family phage prohead protease	A0A1B2APW1	Phage_Wrath	3.4e-19	39.2
WP_159312712.1|3789827_3791162_-|portal	phage portal protein	Q6JIM9	Burkholderia_virus	1.5e-57	36.1
WP_159312713.1|3791158_3791338_-	hypothetical protein	NA	NA	NA	NA
WP_159313925.1|3791331_3792792_-|terminase	terminase	G9FHH3	Rhodococcus_phage	2.8e-94	41.4
WP_159313924.1|3792799_3793075_-	hypothetical protein	NA	NA	NA	NA
WP_159312714.1|3793318_3793756_-	hypothetical protein	A0A0F6SJL7	Mycobacterium_phage	1.0e-23	43.8
WP_159312715.1|3793759_3794035_-	HNH endonuclease	A0A1D8ERZ6	Mycobacterium_phage	5.8e-09	45.3
WP_159312716.1|3794050_3794314_-	hypothetical protein	NA	NA	NA	NA
WP_159312717.1|3794492_3794684_-	hypothetical protein	NA	NA	NA	NA
WP_159312718.1|3794773_3794929_-	hypothetical protein	NA	NA	NA	NA
WP_159312719.1|3795004_3795763_-	hypothetical protein	NA	NA	NA	NA
3795448:3795465	attL	NA	NA	NA	NA
WP_159312720.1|3795759_3796263_-	hypothetical protein	Q6VY64	Streptomyces_phage	1.1e-32	47.3
WP_159312721.1|3796259_3796808_-	hypothetical protein	NA	NA	NA	NA
WP_159312722.1|3796804_3798178_-	hypothetical protein	NA	NA	NA	NA
WP_159312723.1|3798174_3798453_-	hypothetical protein	NA	NA	NA	NA
WP_159312724.1|3798449_3798608_-	hypothetical protein	NA	NA	NA	NA
WP_159312725.1|3798764_3799382_-	hypothetical protein	NA	NA	NA	NA
WP_159312726.1|3799378_3799645_-	hypothetical protein	NA	NA	NA	NA
WP_159312727.1|3799641_3799974_-	hypothetical protein	NA	NA	NA	NA
WP_159312728.1|3799970_3801050_-	DNA cytosine methyltransferase	I4AZL4	Saccharomonospora_phage	3.4e-68	45.2
WP_159312729.1|3801046_3801244_-	hypothetical protein	NA	NA	NA	NA
WP_159312730.1|3801571_3803182_-	DEAD/DEAH box helicase family protein	A0A125RNY6	Streptomyces_phage	5.1e-97	52.9
WP_159312731.1|3803539_3806188_-	hypothetical protein	Q6J7X6	Actinoplanes_phage	5.4e-35	29.5
WP_159312732.1|3806184_3806427_-	hypothetical protein	NA	NA	NA	NA
WP_159312733.1|3806423_3806684_-	hypothetical protein	NA	NA	NA	NA
WP_159312734.1|3806676_3806967_-	hypothetical protein	NA	NA	NA	NA
WP_159312735.1|3806963_3807257_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_159312736.1|3807609_3807963_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_159312737.1|3808130_3808364_+	hypothetical protein	NA	NA	NA	NA
WP_159312738.1|3808368_3810036_+|integrase	site-specific integrase	A0A0U3U8Y8	Bacillus_phage	6.2e-13	23.1
3819032:3819049	attR	NA	NA	NA	NA

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NZ_CP047147|6257097:6386481|DBSCAN-SWA
GTCATCGCTCCGATGTCCTTTCGGCGGCGGTCACTTCGACCGTGTAGGGCATGTGGGCCGGGCGCGCCGCCGCGACGAGGGCGTCGAGGCGGTGGGTGTCGGCCGGGGTGGGGTCGGGCAGCCGGAGCGCGACGTGCAGCGCCGGCCGGGCAGGACCGGGGAAGGGGCCCAGCGGGCGGGCGCTCCACGCCGCACCGCCGGACTCGGTGATCTCCGGCGTGGTGCCGAACGCGAGCCGCACGGTCTCCGCGAGCCCCTGCCGGGTCCCCCGGATCCGGTGCAGGCGGGCGGTGGCGGCGACGATGGCGCGCAGCCGGGGATCAGGCTCGGTGCCGTCGGTCTCGGCGCCGATCCAGGTGCCGAGCCAGCGGGCGAAGTCGGCGGGCGTCAGCGCCGGGTCGAAGTAACTGTCCAGGCAGTCCAGGGTGTTGAGGATGGGCGCGAGGACCTCGTCGAGCCCGGCGACGAAGCGCTGGGCCAGGTCGTCGTCGGCGAAGACCGCGGGCAGCATCGCCGACAGAGGGGCGGAGGACTCCAGCCCGTCGACCGAACCCCGGGCGCTCACGGGGTGTCCCCGACGACCCGGACCCGGTGGTCGTAGGAGAAGACCAGTGCGGGTGCCTCCAGGTCGATGCGGTCGGTGGGGTCGCCGCGCTTGCCGGTCAGCGGGTCGGCCGGGTGCAGTACGACCTCGTCGACGAGTTCGACGCCGGGGACGCGTTGCAGCACCGCGAAGACCTCCCCGGCCTGCACCGGGCGGCCGAAGGGCCAGCCCCGTCCGTCGGCGCCGCCGGTGAGCGGGTCGAGGTGGCGGTAGAGGGCGTCGTGGGCCGCCCGGCGTACCCGGTCGGTGTCGACGGCGCGGAAGGCGTGCACCGTGGCGACCACCGTGACGCCCTGGTAGAAGGGCGGGCCGACGGCGAGCCGGGTGCCGATCAGGCGGCGCTCGTCGAGCTGGCGGGTGATGCGGTCCAGCAGGGCGTCACCGGGGACCAGTTGCTCGAAACGCAGCCGCCCGCCGGGGTCGGGGACGGCCTGCGGGACGACCAGGACCCGCACCGCGTACGCCCCGTGTTCGCCCTCCTCGCCCTCCAGGCAGGTGATTCGGGCCGTCTCGGGGGCGGCGCGGCGGGCCAGTTCCTCGTAGTCCCGCAGGGTGACGGCGCGTTCCTGGGCGCGCAGGGTGATGGGGGCCCGCAGTTTGGCCTCCTCCACCGTCTCGCCGTCGACCCCGCCGCGCGCCGCCTCCCGGTTGACGACCTCCCCGACGTAGGGGATGGAGGTGCGCAGGACCTGGACGGCGTGGCGGGCGACGTTGCCGGCGCGGCCGCCGCCGGTGCGGTAGCGGCGGGCCCGGATGACGGCGCCCTTGGGCGGGACGGCGCCGTACTGGCGCAGGGTGCCGTCGCTCTCGCGGACCGAGGGGCCGAAGGCGATCTCGCCGGTGGCGCCGTCCAGGGTGATGTGCGGGTCGTCGGGGCGGGAGGAGGCGAAGTGCGGGACGACCTCCCAGTCGTGCCACCCCTCGTGCGTGGCGGTCTGGAGCAGCACGGGCGGGGAGTCCGCGACGACCGGGGCGTGGGCCAGGCGCAGCCGCTGGCCGGGCAGGCCGGTGGACTCGCCGAGCGCCTCGTCGCGCACGGTCTCGGCGTGCACGGCGCGGGTGGTGCCGCCGACCGTGTACGCCTCGGCGGAGCGGATGGTGGGGGAGGTGGTGTAGAAGGGCTGGCCGGTCAGCGGCTCGGTGACCCGGCAGCGCACCCAGCCGGCCTCGTGGCCGCCGTTGCGGGAGAGGACGTGGCCCTCGGGCAGGTGGAGCACGATGTCGCCGGGGCGGTTGAGGCCGCCGGTGCCGTCCCGGTCGACCTCGCAGGGCTGCCAGCCGTCCTCCGTCCACGCCTCCCAGGAGAGCGGGGGCTGGCGCGGGTCGACGCCGACACCGTCGACGCGGCTGTCCAGTTCGAGGGCGAGGGCGCAGTGCGGGGCGGCGGCGGTGAGGCCGATCAGCATGCAGTCGCCTGGCTCTGGTGCCTCGGAGAAGCACAGCAGGTCCTTGCCCTCGGCCAGTTCGGTGGTGCGGTCGGTGACCGGGCCGCCCTGGCGCTGCACCACGAGATGGCTGAGAGCGGTCGGCACGATGTCCAGCCCGCGCTCGGTGGCGAAGACCACGGCCTCGTCCCGCTCGGTACGGGTGGTGGCGACCTCGGTGCCGACCGCCACCGCCACCGTCTCCTCCTGCGGCGCCGAGAGCCAGAAGGTCACCTCGGTACGGGCGGCCGACGGCGGGAACAGGGTGATGCCGACCAGGTCGAGGAAGGCCAGGTGGTTCTTGTCCGGGACCCGGTTGAGCCGGTAGACGATCTGGTCGGCCATGTGGGCGACGGTCTCGACGAGGGTGACGCCGGGGTCGGAGACGTTGTGGTCGGTCCACTCGGGCGCCCGCTGCTGGATGTAGCGCTTGGCGTCGTCCACGAACTGCTGGAAGCGGCGGTCGTCGAGGTTGGGGGAGGGCAGGGACATCAGCGTTCGCTTTCGGGGAGGGTCCCGGGGCCGTTCGGGCCGGCGGCGCCGCCGGGCGTGCCCGGCTCGTCGTGGGAGGGGATGACGTAGAAGGGGAAGACGAGGCTGCGCGGGTTGTTGGTGCCGCGGATGGCGTAGCGGACGTCGATGAAGAGCACGCTGCGGTCGTGGCCCGCGGTGACCTCCACGTCGTGCACCTCGATCCGCGGCTCCCACCGGTCCAGGCTGGTCAGCACCTCGTGCTGGATGCGCCCGGCGGTCTGCTCGTTGACCGGCGCGAAGACGAGGTCGTGGATGGCGCAGCCGAACTCCGGGCGCATCGGCCGCTCGCCGGGCGCGGTGGCGAGGACCAGCCGGATCGACTCCTCGATCTCGCGCTCGCCGCTGACCAGGGCGATGCCGCCGGTGGGGCCGATCCGCAGGGGGAAGGCCCAGCCGGAGCCCACGAACTGTTCGGACATCAGGACTTCCCGTTGCTGAGGCGGTGGGGCAGGGGGCGGCGGTCGTGGGGGCGGTCCGTCACAGCGGCACCGGTTTCCCGTTGATGGTGACCACGCCCATGAGCGGGATGTTGATCGCCCGCATGCCGACGCTGGCCACCGAGTTGATCTGGACCGTCCCGATGGCGTTGAGCAGGGCGGTGCCGCTCGCCTGGAGGTTGAGGACGCCGGTCGCGTTGACGTTGAAGCCGCCGGCCAGCGTCCGCAGGTTGGTGGCGCCCCGGCTCTGCATGTTGATGATCCCGCCGCTCTTGAGGGTGAGCTTGCGGCGGGCGCTCAGGGTGAGGTCGGTCCCCGCCTCGACGGAGACGGACTTGCCGCCCTTGATGGTGACGTCCCCGTCGCTGTCGACGGTGATCTCGGTGTTGGTGCGGTCGAGGTTGACGGTCAGCCGGCCGTCCCCGGAGGCGACCCGCACGCCCTGCTTGCCGCCGGAGCGCTGGCTGAGCAGGTCGACGCGGTTGCCCTGGCGGTCGGAGAGGGTGTGCCGGGTGGCCTGTTTGCGCAGCCCGTCGTGGAGCGGCACGTCCGGGACGCGGGTCGGCAGGTCGACGCCGTTGTACAGCCCGCCGATGACGAAGGGGTGGTCGAGCGCGCCCCGGTCGAAGGCGACCAGCACCTCGTCGCCGACGTCCATCGGGAAGATCCCGCCGCCGCTCTTCCCGCCGAGCTGCACGCACCGTGTCCAGTCGCTGACGTACGCGTCGTTCAGCCAGGGGAAGGTGAGCTTGACCCTGCCCTGGCGCAGCGGGTCCTGCACGTCGGTGACGACGGCGTTGGCGACGCTGGGCAGCCGGGAGGCGCCGCCGCCCGCCTCACTGCCGCCCGAGGCCAGCCCGTACAGCGAGCGCCACTGGCGGCCGCTGACGGTCACCCAGGACTCGTAGTGCCTGCCGTCGCCGAAGACGTGCCGCACCGAGGTCACCGTGTACTTGCCCTCGAAGGGCTCGCCCACGTCGGAGAGGGCCACCGGGACGCCGGGCCGCAGCTCGGGGTTGCCACGCGCGGCCACCTCCAGCTCCGCGAAGGACGAGGTGACGTCGGTGGCGAGGGCCTCGGCGGCGTGCTGCACCTCGGACTGCTTGTCGTACGGCGACGCGGTCTCCACCAGCGTCGCGGACTTGAAGGAGCGGGCGATCTCGCCGGGGGTGACGCCGATGCTGATGCCCGGGTCGGTGGTGAGGGTCTTGACCTCGGTGATCTTCTTCTTCGTGGTGACGTTCCAGCCGCGTGTCTCCACCTTGTTGACCTGGTCGGCGGCGGTGACGGCGGCCCGCAGCCGCAGGATGTCGTGGCCGCCCTGGAGCACGAACGGGCTCTTGTCGCCGTCCGTGCCCGGCGAGGGCGCCCCGGAGGACGCCTTGGGCTTCACGAACTGGAACTTGCCCTTCGCGTCCAGCGACATCACCGACTCGTTCTCGTCGGCGAGGCGCGAGAGGAAGTCCCAGTCGCTGATGTTGGGCTGGCTGATGAACTCGTAGAGCGCCGGGGTGGACTGGATGCGCCCGATCGGCACGCCCGCCTTCGCGGCCAGCCTGCGGGCGATGTCGGAGGCGGTCTGGTTGCGGTACGCGGAGACCCGGCGGCGGCGCATCAGGCGGTGCCCGAAGTCGTAGCCGCGTACGACGGCGAAGCTGCCGGTGCCGTCGTAGTCCGCCTCCAGGCCGGTGACCTCGCCGGTGAGCAGCGGATCGCCGAGCCCCTCGCCGTCGGCGACCGGGGTCAGCACCACCTCGGTGCCGAACTTCACCCCCAGCTCCCCGAGGACGATCCGGTACGGGTCGCGGAAGGTCAGCCGGAAGGCGGCGGGCACGCCCGCGCCCTGGTCGACCCAGCCCTCCACCAGCAGCGGGGCGATGTCCTTCGGAAGCTCGGCCCCGCCGATCGAGACCTGGATGACACTGGAGAAAGCGGTCCGCACCATCAGCGCCGCACCTCCTCGGCGGCGGGCAGCACCAGTTCGGTACCGGAGCGCAGCCGCGAGGGGTCGTCGATGTTGTTGGCCTCGGCGATGGCCCGCCAGGCCGACGCCTCCCCGTACTCCCGCCACGCCAGCGACTGGAGGGTGTCGCCCGCGACCACGCGGTGCACCCGCTGCGCGGTGAGCGCCCCCGAGGTCGGGTTCTGGCCCTTGGTCTTCGAGGGGATCTCGTGCAGCCGCATCTGGCAGGTCGCGCGGATCGGCACCCCGGTGGTCCCGAAGAGCGTGTAGGACGCCTCGACCGAGGAGACGTACGCCGTGAACCGGGCCGTGGAGAACGCCCCCCACTCGAAGACCACCCACGGCGGCGACGGCTGTTTCGCCGCGATGCTGCGGGCCGTCGTCTCGCAACAGCCCAGCAGCGCCTCCACCTTCTTCAGGACGGTGTTGCCGGTCGGCTCGCCCGAGGAGTCAAGGAACACCTCCACGGTCATCTCGCGCGGCTCGGGGCCCAGGAACTCCGGCTTGCTGCCCTTGCGCACCGCCGGGCTCGGGGTGAATTTCCAGTTGGCGCCGCGGCTGATGGTGAGCTGCGCCGGGTTGAAGTCGAAGTGGAACGTCCGGATGAGCCCGCCCGGCGTGGTGCTCTTGCCGCGCGGTGGTTCGTGGATGGAGAGGGAGGCGCGTACCAGGCTCTTGCCCGCGCCCTTGCTGCTCTTGGCCATGGGGTCCTTCTCTGCGGTCCGTCAGGTGGTGCGGTTGCGGACCGCGCGTCAGTCGGTGAAGCCGTGGTGGGCGATCTCCAGGACCTCCGTGGCGACGGCCGGGCTGGCCGGGTCCAGGGAGGGCCCCTGCCAGCTGACCGGCAGGACGTCGATCAGCCCCCAGCGCGCCACCTCGGAGCCGTCCGCGCGCAGCGCCGCGATCTGCGCGGTGGGCCGTTTGATCCCGGTCTGCACGGAGGAGATCCACTTGGCGACCTTGGTGGTGTCCGGGGTGAGCGGACGGGTCAGCCGGATCGTGGAGAAGGTGACGCGGGTCGGCAGCGTCCACACGAAGCCGTTGCTGCCGCCCTCCTGCCGGTGCTCGACCTCGACCTGGGAGGACAGGCCGTCGCAGCCGTTGAAGTAGCCGAGGCTCTCCCCGTCGATGGTGAGGGTGAACCAGATCGTCGAACCCGGGTCCTGACGCGGCATCGGTACGGCGCCCTTTCTCTCGTGTCGCCGCCCGCCGCCGGAGCGTGCGGGCGGCCGGTCGGTGGTCGGCCGGTCCTCTCGGAGCGGTCGGCCCGGTCAGCCCCGGGGGTCCCGGAGCCGCCCGATCCGCTCCCGGTCCATCCGCAGTTCGGTACGGACCAGCCGGGTGACGCGGCCGATGATCCGGTGCACCAGCTCGTCGAGCTGGAAGTCGGTCAGCTCCCTCGGGTCCATCCCGCCCTGGGCCACCGCGCTGTACGCGGGCGGCTCCTCGCCGGCCGAGGACGACCCCCCGGAGCTGCCCGGTGTGTACGGCGGCGGAGCACCGGGCGCCGACGCGCTGTAGGCCGGCGGCGGCTCGTAGGGAGGCGGCGGCCCGGCAGGCGCCGGGGCGGGCCGCGACCGGCTCAACGAGGCCGCCACCGCTGCCGCCGCCGAGGCCGCGAGCGCCCCCGTGGTACGGCCCGGGACACGCTGCACGGTCGGCTCGGCCGGCGCCGGGGCCGGCGTCGGCCGGACGAGCGGCGTGACCGGCGGCGCCGGGGGAGGCGTGAGCGGGGCGACGCTCGGCGCGGGCCCGGCGACGGGCGCCGCGACGGGCGCGGGCCGCCGCAGCGGTACGACCGGCGGAGCGGTCCGGGCGGAAGCCACGGCCGCCCGCTGGACGGGCGGAAGCAGCGCGGCGGACGGCGGCCGGGGCGCGTCTGCCCCGGACGCGGGCGGCGGAACGGGCCCCGGGGCGGCCGGCTGCGGACTCGCGGCGATGCCCGGCGGAGGCGACGCGGGCGCGGGCACAGGCGCAGGCGTGGGAGTGGGTCCGGGAGCGGGCAGCGGGGCGGGTGCGTGCGGCGGCTTGGCGACTGGTACGGGCGCCACCGCCCGCTGCACCGTCGGAGACGCGGGAGCGGACCCTCGGGCGGCGAGCGGAGTGGTGCCCGCCGGGGGGCTGGTGAGCGGCGCGCCGATCGGGGAGCGGCGGCGTGCGGGGGTGGGGCTGGGACCTGAGGGGAGGCTGGAGGCCGAATCCGGAGCAGGAGCAGGAGCCGGAGCAGGAGCCTGCGCCGGGGCCGGTGCGGAGGCCGGGCGGGAGGCCGGCGCGGCCGAAGGGGCATCCGGTGCCTTCGCGACAGACTTGGAGGCGACCGGCCTGGAGGTCACCGGCTCGGACGTGACCGGCTTGGAGGAGACCGGCTTGGAGGAGACGGGGGCGCCGAGGCCGGACCGGGCTCGCTGGACCGGGGGAGCGGACGCCGAGTGAGGCGAACCGGCAGCGCGGCCCGCCGAGACCGAGGGCGGTACCGGGCCTGCACCGGAAGGCAGTGGAGCACCGGGCGTACGCGGTGCCTGCTCCGGCGAGGGCGCGGGGAGCGGCGAAGTACCGGGAGCCGGTGAACTGCCGCCGCCTCGGCGGGACTCCGTCGCGGGCGTCCTCGTCTGCCCGGCGCGGTCCGCCGGTGCCTGGCTCGCGGACGAGGGGGCCGCCTTGCGCTGGACGGGCGCGGTCGCGCCGGTCGCGGGGGACGCGGCCGGGGGACGCGCGGGGCCCGCCGTGCCGGAAAGCCGGTTCGGGCGGGACGACCCGACGCCTTCGGTGCCCTTACGGGGCGCCGGGGCCTGACTCGGTGAAGTCGCTGAAGCCGCCCGGGTGTTGTGCGCCGGGGGAGCTTCGGCTCCGGTACGCCCGGCGGCCCTTTCCGGCGCGGGTCGGCTCGGGCCGGTGGAGGGCGACGGGGCTGAGGACGACGGGGCTGAGGACGAGGGGATCGAGCCGCTCGACGAGGGAGAGCCGGACGTGGTGGCGGCCCTGCTCGCCGGAGCGGGCCCGGAGGGGGCGGCAGGCGGGGTGGGAGGCGCGGGCCGGGACGAGGGCGCGGGGCCGGACGGCGCGGCCGGCTCCACGGGGTTGCCGGACCTCGCAGGCGAGGCGTGCCCGGTCGGGGAGGAGCCGGCCGTCGGCGAGGCGCCCCCCGGCGCCCCGCCGACCGGGCCCGACCCTCTGGCCGAGTTCTTGGCGGTGGCCCGCTGGACGGGCAGGTCCGGCTGCGACTGTGCGGGGGTGCGCCCGGCCGGGGGCGCGGAGGCGGGACGTACGGCCGGAGCGGGCGCGGGAGAAGGGGTGGCGGATTCCGTGCTGTTGCCGGTTCCGGGCACCGTCGGGGCGCTTGCGGGCCGCTGATTCCCGGCAGCCGGTGCGGGCGTGGCCGGTCGTTCCTGGCGGGAGACGGCACGCTGGACCGGGGCACCGCCCGGCGTGCTGCCGCCGCCGGTGGGCCTCGTGGACGGACGCGCGGGAGCACTCGCGGCGCCGGAGACCGGGGCGGCATCGGCGGCCGCCCTGGTCTCCGGCGCCTGTCCCTGGCGGGGGCGCTCGGGCTGCGGTGCCGGTGCTGCCGGGGGCGGGGGAGTGGGGGCACCCGTGGTCGCGGTCGGCCGAGGCGGGACTCCCGAAGGTCCTTCGGCCCGGCCTGCGGGGGCGCGGGTCGCTTTGTCGGTACGGGTGACCGGGGCGGGTGCGTGACTATTGGTCGATGTGTCGACAACTGGCTTGTCGGCAGGCTTGCTTGCCGCGCCGGCCCGGGGCGCGGTGGCCCGCTGGACGGGGACCTGCGGCGACGGGCTGCCGGTGGGGCGGGGTGACGCGGAGGGGGTCTTCCGGCTGTCTGCGGGAGCTTGCGCCGGGGCGTTTCCTCGCTGAGCGGGGCCGGACGGCGGCCGCCGGTCACTCGCGGGCTGCCCCGCGTCCCGCGCGGACTGCCCTGGGGAGGGCTCCGGGCCGGGGGCGTGTTCGCCGCCGGTGTGTGCTCCCGCCCCGGACGGGGTCGCCGTCCGGGGCGGGGCGCTCGGGGTGGCGGAGCGGGCAGCGGGCAGGGCACGCCGCTGCACCTGCCCCGTGCTGGACGGAGCCTGAGTCAGCGACTGCCGGGGCGCGGCCGGTTCCGACGGGACCGGTGTCACGCGCGGCCCCTGCGGACCACGCGGAGCCCGGGCGGACGGGCTCGCCGCCGGGGTTGCCGCCGGAGCCGCCGAGGGCGCCCCGCGCGGAACCGCCCGCTGGACCGGCGGAGCCGGCTCCCGGCGCGCGGCGGGACGTTCGGCCGCCCGCGCGCCCGGCGAGGGGCGCACCGGGGCGGGGCTGCCGGTCCCCGGCGCGGACGCCGTCCCGGGCAGCGCGCGCAGCGGTGCCGCCGGCGGCCTCGGGGCCGGGGTGCCGGCCGCCGGGGCGGCGGTCGGCATGGGTCCGGCGGGCCGTTCCATCCCCGTCACGGGCGTCCCGGAGGTGCCGAGCGCGCCCGGCAGCAGGCCCGCGCCGGCCGCCGGGTTCAGCACGGCCGGGGAGGCCGTCGCGGTGAACGACGGGTTCTGCCAGGTCGGCAGGGTGCCGCCGAAGGCGTTGTCCGCCACCCCCGCGCCTCCGGCACGCGCGGCGAGCTGGACCGGCGGCAGCCCGGACCACGAGGGCACCACGGGCGCGGGCGCCGGGGACGCCTCCGCCACCGGCCCCGACGGCACCGCCGGCGCGGGGCCGGCGGAGTCCGCGCCGGGAGTCTCCGGCGTACCGCCCCTGCGTCCCCGCAGCCGCTCCAGGAATCCCACCGCTCAGCCCTCCGCCCGCGTCACCAGGGACGCGATCTGATCCGTGTACCGGCGGCGGTCGTGGTGTTCGAGGTCCAGGATCGCCTCCAGACCCCAGTGGAAGTGGAAGGCGACGTACGCGATCTCCTCGTGCAGCCGGTCGGTCGCGTACGTCACGATTCCCCCAGGCGGCTCCCGCCGAGTTCCACCTCGAACGGTTCGGAGCAGTGCGGGCACCGGACCCCGGCCCGGGTGTGGCCCTCCGCGTTGATCTGCCGGTAGAAGTCCTGGAGGAACGCCAGGTCGGAGGCGAACATGTTCTCCACGATCCCGTCGTGCACCATCGGCAGCTCGCCGAGCCGGGTGATGACCCGGCCCAGCAGCACCACCGAGAGGTACGCCGGGTTCTCCTGGACGCGTACGTCGCGCAGCGGGACCAGTTCGTCCCGCGCCGTCGACAGGCGCATCACCCCGTCCCGGTGGACGGTGCCCGACTCGTCGACGTACCCGCGCGGCAGCTCGAAGGGGAACTCCGTGCGCAGCCGCTCCCGCTGCTCCGGTGCCGGAGCCTCGGGGGGCGCGGGTGCGGCGGCAGGAGCGGGACGGGGGAGATCCGCTCCTGCCGCCGCGGCCGAGGGGGCGGCGCCGGGAGCCGCGGCGGCCGTGCGCCGCATTACTCGATGACCAGTTCTTCGAAGACGATGGTCACGGACTCGGTCAGCGCGGCGGCCTCGCCCGCCTTCACCGTGCTGGTGTCGATCTTGCTGCACCAGGCGTTGCGCAGGTTGTAGCGCTTCACCGGGTTGTCCTCGAAGTCCATCATGATGATCGAGGCGTTCTTGCGGGCCGTGGCCATCCGGCCGTTGATCGAGTCGTTGATCCACTGCGTGAACGACGCCGACTGGGTCATGCCGCGCACCACCGTGCACTGGCCGTCCTTCTGCGTGCCCGGCAGCAGCGAGACCCCGGCCTTGCCCGTCGCGCCGTTGTTCTGCTGGTACTTGATGACGTCCTGTTCGAGGGTGAGGCCGCTGACCTCGGCGAGGTACTCGACCATCACCCCGTCGATCTGGAGGCCGAAATTGTGTGAGGTGAGGGCGTCACCCGGCTGGAGACTCATCTGTTCGCTGTCCTTCGGGAATGCGGTGGAATGCGGGAAAGCGTGGGACCTGCGTGCGGGAGGCGGAGCCCGGCCTACTCCTCCAGCTCACCGCTGCCGCTGGAGAACTGCGCCAGCCGGAAGATCACGAACTCGGCGGGCTTGACCGGCGCGATGCCGATCTCGCACACCACCCGGCCGAGGTCGACCGACTCCGGCGGGTTGGTCTCCTGGTCGCACTTGACGTAGTACGCCTCGTCGGGGCTCTGGCCGAAGAGGGCGCCGTTGCGCCACTCGTTGACCAGGAAGGCCGAGATGTTGCGGCGGATGCGCGCCCAGAGGTTGTGGTCGTTCGGCTCGAACACCACCCACTGGGTGCCGATCAGGATCGACTCCTCCAGGTAGTTGAAGTACCGGCGGATGTTCAGGTAGCGCCAGGCCGGGTCGGAGGCGAGGGTACGGGCGCCCCAGACACGGATGCCGCGGCCGGGGAAGGCGCGGATGCAGTTGACGCCGATCGGGTTGAGCAGGTCCTGCTCGCCCCGGGTGATCTGGAGCTCCAGGTCGACGGCGCCGCGCACCACCTCGTTGGCGGGCGCCTTGTGCACGCCGCGCTCGGAGTCGTTGCGGGCCCAGATGCCGGCCACGTGGCCGCTCGGCGGGATCAGGCGGGCCTGTCCCGACGCCGGGTCGAAGGACTTGATCCAGGGGTAGTACAGGGCCGCGTACTTCGAGTCGTACCCGGCGGTCTCCTGGCGCCAGACGCGGATCTGCTGGGCGTTCTGGCTGGGCGGCGGGTCGATGATGGCGACGCGGTCGCCCATCAGCTCGCAGTGGGCGATGAGGCCGAGCTGGACGGCCTTGACCGACTCCAGGTCGATGGCGCCCCGCTGGTAGGCGGCCATCAGGTCGGGGACGGCGACCATGGAGATCTCGTCCACCGCCTCCAGGCCGCCGAAGCCGGTGCGGTCGGCGGAGTCGCCGAGGTACTGGGCGGGGCCGGGGTTCGCCGGGTTCTTCGTGGCCGGGGCGGTGGCGGGCTCGGCCGGGGCGGTGGGCGGGGCCGCCGGGGTGACCGTCTGGTTCTCCGGGCGGGCCAGCTGCCCGGTGGGCGCGGCCTCCGTCACGGAGATCAGCTTGGACTGCTCCTTGACCTGCGTGACGACGTAGGAGCGGGTGCCCTTCTTGGCGCTGACGTCGAAGGTCTCGACGGCCTTGCCGCCGTCCTTGACGACCAGCTTGAACCGCTCGGCCGCCCCCTCGCCCTCGGGGTCGGCGACCTCGACGGTGAGCGGGCCCTTGGTGCCGGGTGCGAGCGCGGTCACCGCGAAGGTGCCGAGCTGCGCGGGCTCGGCGGCCGGCAGCGCGGCCGGCGCGGTGGTACCCGTCACCGCGGCCGGGCCGGCCTCGCCGGCGGTGCCCTCGGCCGAGCCGCCGACGCGGACCACGTAGGCGGCCGAACCGCCGTTGTTGAAGAAGCCGTAGACGGAGTGGGCGAGGAAGTACCCCTCGGTGAAGTCACCGAAGGCCGCGACGTACTGCGTCCAGTTGGTCACCAGCGTGGGTTCGTTCAGCGGGCCGGACGGGGCGAGGCCCACGAAGGCCGCCACCGAGGTGCCCACCCCTTCGATGGGGCGCGAACCGCTGGCCACCTCCTCGACATAGACGCCGGGCGACAGGTAGGACGGCATGCTCTGCTCTCCTCGGGGTACGAGACAGGACGTCGCTCACCCTCACGCGCGAGCCGCTCTCGCCGGAACGGCCGTGGGGGCCGGTCGCGGGGCAGCAGTGCTGCCCCCAACTCTGCCCGCAGGGGCAGCCGTCGCCGGGCCGGCCCGGCGCTCCGGCAACCAGGGAGGGGTTTCGCCGTGGAACTTCCCCGGGGAACGCCGCTCCACGCCTCGCCGGCCGAAGCGTGCCCGGCGACCCTGCCCGCGCGGGCAGCGAGGTCTGCCCCCGTGGCCCGTGACGGAGCGTCGGACGTTGTCTAGCGTGGCTGCGTGAGCCTATGGACTTCCCTTGAGCCCGCGTCGGCGAGCGTCGAGCCCGGTGGCTCCGCGCAGGTGCGGCTGCGGGTGCGCAACACCGGCGACGTGGTGGACGAGTACCGGTTCGAACCCGTGGGGGCCCTCGCGCCCTGGACCCGGGTGGAACCGCAGACGCTGCGGCTCTACCCCGGGACGACGGGCACGGTGGAACTGACGTTCTCCCCGCCCCGTACGCCCGACGCGGTGGCCGGCCCCAACCCGTACGCGGTGCGCATCACCCCGACCGAACACCCCGAGGCGGTGACCGTCCCCGAGGGCAACATCACCGTCTCCCCCTTCACCGAGGTCCGCGCCGAACTGGTGCCGGTGACCGTCAAGGGCCGTTTCCGCGGCCGCCCCCGGCTGGCCGTCGACAACCTCGGCAACACCAAGGTCACCGCCTCCGTCAGCGGCAGCGACAACGGCGACCACCTGTCGTACGAGATCCGGCCGCAGAACGTGCAGATCGAACCGGGGCGCGCCGCCTTCGTCGACACCGTGGTCCGGCCGCGGCAGAAGATCTGGTTCGGCTCGAAGGAGGAGCGGCCCTTCACCCTGACCCTGCGCCGCTCCGGCGCCGAACCGGGCGAGGTGGAGGGCACCTACGTGCAGCGCGGGTTCCTGCCGCGCTGGCTCGCCACCTTCCTCGGCATCTTCATGGCCCTGGCCATCGCCTTCGTGATGATCTGGATCGCCTACAAGCCGCAGGTCCGCACCAGCGCCACCGAACAGGCCGCCGCGGCCGACGCCCTCGCCCCCAGCCCCACCCCGGACCCGCCGAGCCAGGCGCCGCCGCCCGAGCCCGAGCCGGAGCCCAGCGAGGAGCCCGCGGGCGGAGCCGACGGCGGCGGCGGAGGCGAGCCCTCACCGACCGAGGAGCCGGGCGTGGTGCCCGCCGAACGGGTCCTGCTGCGCAACACCACCACCGGTTACTGCGCCGACGTCCCCGACCGGGGCAAGGGCAAGATCAACGAACGGGTCCAGCAGGCCACCTGCCACGAGACGGGCGACAACCAGCTCTGGGACCTCGTGGTGACCCAGGAGAAGGGCGGCCCCAACGGCGCCCCGCTCTTCCTGATCCGCAACACCATGGACCGGCTCTGCATGGACCTGCCGAAGTTCGGCCCCCAGCCGATCAGGACCCCGATCTCGGAGTTCACCTGCGACGGCACCATGAACGACAACCAGCTCTGGTGGGCCCAGGAACTCGACAACGGCGCCTACTGGATACGCAACGCCGTCAGCAACAACCTCTGCCTGGAGGTCGCGGGCTCCGGCGACGGCAAGATCGGCGCCCGGCTGCTCATCTTCACCTGCACCCTCACCGACGACCAGGAGTGGGAGATCATGCCCACGCAGCAGAAGACGGGCTCCTGAGAGAAGGCCGGCCGGGGCTCCGGTGAGGGCGGCTCACCAGCCGCCCTCACCGGGCACCAGGCGGCCCGCCTTGCGGTACTCGCGGCGGGCACCCTCCAGCAGGTCCCCGCCGGACACCGGGGTCCCCCGGCCGGCCGCGAGATAGGCGGCGGTGACCACGGCGCTGCGGATCGACCCGCCGGCCAGCTCGAACTCCCGGGCCAGCTCCGCCGGGTCGGTCCCCTCCTCGTGCGGTACGTGCGAGAGGCCGTGCCGCCACAGCGCCAGACGCTGCCCGGCGTCGGGGAAGGGGAAGTCCACCACCAGGTCCAGACGGCGGGTGAACGCCTCGTCGATGTTGGCGCGCAGGTTGGTGGTGAGCAGCGCGATCCCCTCGAAGGACTCCAGCCGCTGGAGCAGGTAGGCGCTCTCCATGTTGGCGTACCGGTCGTGGGCGTCCTTCACCTCCGAACGCTTGCCGAAGACCGCGTCCGCCTCGTCGAAGAGGAGGACCGCGTCCGTCCGGTCGGCCTCGGTGAAGATCCGCTCCAGGTTCTTCTCGGTCTCCCCGACGTACTTGTCGACCACCGAGGACAACTGGACGACGTACAGGTCCAGTCCGAGGTCGGCCGCGACCACCTCGGCCGAGAGCGTCTTGCCGGTGCCGGACTCGCCCGCGAACAGCCCGAGCACCCCCCGGCCGCGCCCGCCGCCCGCGTTCAGCCGCCACTCGCCGAGCACCCGGTCCCGGTGGCGGGCGCGCAGCGCCAGCTCCCGCAACTGGCTGAGCGGCCCCTCCGGCAGCACCAGATCGTCCCAGTCCACGGCCGGCCGGATGCGCCGGGCGTGCTGTTCGAGGCCGGAGGCCGACTGGCGCCGGGCGGCGCGCCGGACGTGGGCCGCGCCCACCGGCGCGCCCTCGAACTCCGCCAGCGCGCGGGCCGCCCGCGCCGCCCGCCGCACCCGGTCACCACCGAGCCGGTACGGGGCCACGGCGGCGGCCAGGTCGAAGCCGTCCGCGTCCGCGCCGAGCGCCGCCCGCCACGCGGCCGTCCCGCCGGCCCGGCGCCCGGGGGCGTCCAGCACCAGCACGTCGGCGGGCGACCACTCCGGGTCGTAGGGGCGGCGGTCCGTCAGCAGCACCGTCACGTCCGGCGCGGCGGTCAGCGCCCGCACCAGCGGACCGGGCCGCTCGGGCAGGCCGGGGACGACCAGGGGCCGCCCGGTCAGCCGTGCCTCGCGCAGCAGCTCCGGGACCCGCTCCTCGGCGGCCAGGCAGCTCAGCGCGGAGAGCCCGGCGGCGGGCAGCGCGGCGGCGAGGACGGCGAGGCCGTCGCCCTCGCGCGGCTCGCGCAGGTAGGCCGTGACCGGGCCCGCGCCGAGCCGGGCGGCGAGCAGCCGGGTGAACTCCGTGGCCTCGGGGTCCTGGGGGAGCGGCGGCGGCAGGGGCTGCAACAGGCCGAGCAGGGCGGCGTCCGGGGTGTCGTCGCCGAGGAGATGCCCCGCCACCCGGTCGGGGACGCGCAACGAACGGGTCAGGAAGGGGCGTTCGGGCTCCTCCACCTCCAGCAGGCCCCAGGCCCGCAGCGGCGCGGAGGCGTGCAGCCGCGCCCGGGCCGCCGCCTGCGAGGTGGGCACCCCGCACAGCTCCAGGGCCAGCCCGGCGGTGGCCCGGCGGCGGCTCACGTCGTCGTTGAGGTAGCCGTAGAGCGGCTCGACGCCCCGGTCCACGTCCGGGGCGAGGGCGATCAGCAGGAGGGCGGTGTCCAGGCCGGTCAGCCCCGCCCGCAAGGCCAGCCGGGCCAGGCGGTCGCCGGGCGCGCCGTCCGGGTGGGCCCCGGCCGCGACGGCGCCCGGGGCGGGCGCGCCGGACTCCTCGGAGCCCTCGGCCTCCTCCTCCGGCCGCCACCGGTCCAGCAGTTGCCGCGCCGCCTCGTCGGAGACGTACAGCCCGCGCAGCGGGTCCTCGGCCGTCGGGTCACCGGCCGCCCGCCGCGCCACCAGGGCCGCCACCCCGTCGCGCAGTACGGCCAGCCGGGCCAGCAGCGCCGGTGCCGCCGCGTCCGGTACGTCCTCGGCCAGGCCGGGCAGGGGCGGGTCGTAGGCGGTCATCACGAGCCCCGGCGGCGGCGTGCCGCCTCGCGGGCCGCGCGGACGGCCGCCACCTGGCGCGGCCGGTGCGAGCGTTCGCCGGAGCGGGGCGGATCGCCGTTCACGCCGCGCAGCCGCACCGTCGCGCCCTCGGTGACCGGCGGGCCCGCGTCGTACTCCGGGTAGGACGGGAAGGGCACCGTCACCACCAGGTCCACCGAGGGCTTCAGTTCGCCGCCGAGCGCCGACCAGATCTCGGCGAGCGAACGCGACTCCGTCTGGATGCCCGCCACCGTCAGCGGCACCGACAGGCCCAGCGCCCCCAGCGCGCCCGGCAGTTCGGCCGGGGGCAGGACCTCGCGGGGCAGCAGCGTCGCCAGGACGGCGGAGAGCAGGCGGTGCTCGTCCTGCGGGGTCTTCGTCCAGGCCGTCACCAGGTAGGAGAGGCGGAACCAGCGGGGCGGGCGGCGGCGCCGCACCACGATGTCCGCCGCGTCGCGGACCGGTTCCTGGCCGCGCTGGCGCCGGGCCACGTCCTCCCGGATGTCGTACAGGTAGGCGTTGACCACGGGGGCGTTGCGCCGTGCCGCCCAGTCCCGGGTGGGCGCCTCGAAGGAGACGTCGATTCCCGACCCGGCCAGTACCCCGGTGCCGAACAGCCCCTTGAGGACCTCGTCCACCTCGTGGATCACTCTCGCGCTCCCGCCTCGCCGCCTGCCGCACCGCCCTGCCGCCGGTCCGCGTGCACCACCCCCGATCCTGCCCGGGGCCCGGCCGGGCCCGCAGGCGCGGCGGGGACGACGGGAGGGCATCGTGGGCTGCCCTCCTGGCCCTCTCGGCTGCCCGTTCGGTCAGATGTATCCTTCCCTGAGGGCAAAGGCCACGGCATGTGCGCGGTTGCGCAGGTGGAGCCGGGTGGTGACCCCGTGGATCACGTTCTTGACAGTGCGTTCGGAGTACGACAACTTGCCGGCGATCTCCCCGGTGTCGAGCCCCTCCGCGATCAGCCGCACCACGTCCACCTCACGTGGGGTGAGCCCCAGCGAGGGACCGCCCTGCTGCCCCACCGCGCCGCGGTGGAGGGTGCCCACCTGGCTCAGCAGGCTCCCCAGCAGGTCCGCCGGCAGGTCGCCGTCGCCGCGCGAGGCCGCCAGCACCGCCGAGACCAGCCGCCGGGCGGTCGCCTCGTGGCGCCAGACGATGGCGCCGACCCCGCACTCGACCACGTCCAGCAACTCGCGCTCCTGGAGCGTGCCGACCACCAGGGCGGCCCGCGCCCCCTCCCCGCGCACGATCCGACGCAGCCGCCCGACGGCGTTCTCGTCGAGCGCGTTCTCGACCACCAGCGCCACCGTGCCCGGCGCCGACTCCTCCCGCAGTTCGACCTCGGGCTGGCGGCGCAACTGGCTGACCGCGCCCTCCTTGCTGATGGGGTCGGCGGCGACCACCGCCACCGGCACGGGCCCGCCCCGGCCGCCGTCGGGGGCGGGAGTGGAGGCAGTCCACGATGAGTTGAGCAACCGTCATCCCCTGTTCACGAGCCCGCCGGCCGGCGCCGACCGCAGGCCTCCAGGCAAGATCCACACTTCTGCCGCCACCGGCCCGGGCGCAATCGTGGACCACCACGAGGCACACCACGAGACCGGTGCCGGCCGCCCCGCCGAGACCCGTGGAAGTCCCCTGTCCTCGCAGGCCGGAGCGGTGTCGGGGGAGAGGCGCGGGCCGCCCGCTCCCCACCGTGACCGTCACCACAGCGCGCGCCGTCGAGCGCGACACGCCGTATCCCCGCGTGGGTCTTCTCACCCCACCGAACCCCGGCGCTCCCGCGTCTCACAGAGCGGGGGAGCAGGATCGAGCACACGGAGGCACCGATGACCCGACCGCCACGCGAGCACCCTCACCACGACGGGCCCCTCGCGGCCGAGATCGAGCGCGCCCGGAGCGGCAGCGGACGCCTGGTCCTGCTGCGCGGCGCCACCGGCACCGGCCGCACCACCGCCCTCGACGCCGCCGTCCGCGCCGCCGCAGCCCGGGGCCTGCGGGTGCTGCGGGCGCGCTGCTCACCCGAGGACACCGGCGTCCCCCTCGCCGCCGTCCGGCAACTGCTCAGCCCGGAGGACGAGTTCGCCGACCTCGTCCCCGAGGGCGACGAACGGGGCACCGCCGCCCGGCTCTGGCGGACCCTGCGGACGTACGCCGCCGAGGCCCCGCTGCTCGTGGCGGTCGACGACGTCCACCTCGCCGACGACCCCTCCCGCCGCTGGCTCCTGGACGCCGCCCGCCGCCTCGACCGATTACCGCTCCTGCTGGTCGCCACCGAACGCAGCCAGTACGACATCGAACCCCGGCCCCCGGGGCTCGCCCAGTCGCTGGCCCCCTCCCTGGTCCGCACCCGCACCGTCGCCCCGCTCGGCGACGAGGCCGCCGCCGCCCTCGTACGCGAGGCGTTCCCGGCGGCCGGCGAGGTGTGGGCGGAAGCCTGCGTACGCGCCGGGGCGGGCGTCCCGCTCTTCCTCCACGCACTCCTCGACGACCTCGGCGCGACCCCCTGGCCGGAGCCGGACGCACCCGCCGCCGACGGGGTGCCCGCCCTGCCCGAGAGCTGCGCCGCGCTCTACCCCGGCTCCTACCCGGCCGCGGTCTCCTGGTGGCTGGAGAACGCCGGGGCCGCCACCGCCGAGGTGGCCCGGTGCCTGGCCGCGCTGGAGGAGGCGTGGCCGTCACCGTCCGCCGCCGGTGACACCGGGACGGACGCCCCGCCGGAGCCGCCCCACCCGTCGGTGCGCGAACGTCCCCCCACCGCAGGGGGGTCCGGCGCGGCCGCCCGCGACCCGGCCGGGCTCCTCGCCGAGGCCGCCGGGGCGGACCCCGCCCGTGTCGCCGGCTGGCTCGCCGCCATGGGCCGGCTCGGCCTGCTCCGCACCGACGCCGCCGGCCGCCCCCGCTACGCCCACCCCCTGCTGCGCGACGCCGTCCTCACCGGCTGGCCCCTGCGCCGCCGGCAGGCGGCCCACCGGGCGGCCGCCGAGGCGATGACGCGCCGGGGCGACCGTGTCGAGGAGGTCGCGCGCCATCTGCTGCGGGTCCCGGCCGCCGGACCGCCCTGGGCCCTGCGCGTCCTGCGCGACGCCGCCACGGTCGCCGTGCACGACGCCCGCCCCTACGACGCCGTCGGCTACCTGCGCCGCGCCCTGGAGGAGGAACTCACCGGCGACCTCAGGCAACGGCTCCTCACCCAGCTCGGCTCCCTGGAGTACGCCTCCGCCGACGCCCCCGCCGCCATCGCCCGCCTCGCCGAGGCCCAGCACCTGCCCGCCGGGCCGCGCGACCGGGTCCGTACCGCCGTCGCGCTCGGCGCCGCCCTGGCCGCCCGGGGCGAGATCCGCACCGCCATGGAGGTGCTGCGCCGCGCGGGCGGCAGCCTCTCCGGCCACCCGGGGCTGGCCCGCACCGTACGGGCCGCCTCGGCGCTCGTCTCCGACGGCGACCTGGCCAGCCGGCAGGAGGTGTACCGCCGGCTCTGCGAGACCGGCGAACGCTCCCCCGAACTGGTGGGCACCGCCGGACAGGCGCTCCTCGTCCGGTACGCCGCGACGGCCGGGCTCGTCTCGGCGCCCGAGGCGATGCGCCGGATGCGGGAGCTGCTCGCCCAGCCCACCGATCCGCTCGCCGAACCCTTCCTCGTCGGCACGGCCGCCGCCGTCGCCCAGTGGGCGGACGAGCTCGACGAGGCGGACCGGCTGGTCGAGCGGGGGCTCGCCGGGCAGCACCCCGGGCTGCTCCACCCGATGCTCGCCGCCCTGCTCAACACCGGCTCCGACATCGCCGCCGCCCGGGGCGACCACGCCCGCCTGCTCGCCTCGGGCCTGGCCGGGCGCCAGGGCGAGCCCCGCGCCGTCCCCACCAACCAGGACGCCCATGTGCTGATGGCGCTGGTGCACACCGGACGCACCGACGAGGCACGCGGCTTCGCGGGCCGCTTCGACCTGAACTCGGCGCCGGACGGCTGGGAGGTGAACCGTTTCCTCTATGCGCGCGGCGTGCTGCGGTCCGCCACCGGCGACCCGGCGGGCGCGGTCCACGACTTCCTGGAGTGCGGGCGCAGGCAGAGCGCCCGCGAGGTGGTCAGCCCCGTCGTCACCCCGTGGCGCAGCGCCGTGGCCGCCTGCCGGCTGGAACTCGGCGGCGGTCAGGAGGCGCTGGACCTGGCGACGGAGGAAGTGCGGCTCGCCCGGGTGTGGGGCACCCCGCGCACGGTCGGCCGAGCCCTGAGCGTCCTCGGCACCGCCACCGGCGGCCGCCACGGCCTGGAACTGGCCGAGGAAGCCGTCGACACCCTGCGCGAGGTCCCCGGCGACCCCTTGGCGGAGCTGATCCCTGCCCTCCTCGCCCAGGGCCGCCAGCTGGTCGCCGCCGGGGAGCGCGGCCGGGGCCGCGTCCGGCTGCGCGAGGCGGCCGAACTGGCCGAACGCTCCGGCGCCGTGCGCTGGCTCGGGCTCGCCTCCCAGGCCCTGCGCGAGGGCGGGGCACGCCATCCGGCGGCGGCCCGCACCGGCTCCGTCGCCCTCACCGACAGCGAGCACCGCATCGCCACCCTCGCCGCCGAAGGGCACACCAACACCGAGATAGCCGACCTGCTGCACCTCGCCCGCCGCACCGTGGAGACCCACCTGACCAGTACCTACCGCAAGCTCGGCATACGGCGCAGGACGGAGCTGCCGGGGAGATTGGAGCGGGGGCCGACCCGGGCCCCGCGGCCGTAGACGGACGCGCGTCCCGTATAGGCTCCCGTGGCTGTGAGCCTCGTAGAACTGCGCAGCCGGCTGCGCCGGTCGGACAGGCCGGCGGCCTTCGCCGTCGTCGTCGGCGATCTGCTGCTCTGCTGCGCCGTCCTCTGGTGGATGGTGGCCGGGGCGGGGGCCACCACCCGCGAGGAGGAGACCGCCTCCTGGATCCTGGGCGCCAAGGTCTACGGGATCTGGCTCGCCGCCGGGATGGTGCTGTTCGCCGGGGCGGGCCTGCCGCGGACCCTCCTCGGGCACCTGGCCGCGATGCTGCTCACGCCGAGTGCGCTGTTCCTGCTCGTGATGCTCCTGTCGCTCAGGTAGCGAGGGCGGTGCGGTCCAGCTCGTCCCCGATCGCCTCGCGGAGCACCTCGTGCCCCGGGCCGAGGGCGTACCGCCGGTCGCTCCACCGGTCCCGGGGGTGGAGCCAGACCGGCAGGCGCACCAGCTCGGCGGGCTCCCACGCGTACCGGGGCCAGACGTGGGCGTGCAGGAAGCCGTCGGTGTTGCCCAGGATCTCCAGGTTGACGCGGAGGAAGGCGGAGTCCGCGCGAGCGCAGGCCCGTTCGACGGCCTCGCCGAGGCGGTCCATGTCGGAGAGGAACTCCAGCCGCCTGGGGCGGGGGAGGTCCGAGAGCCTGTCCACGGCGGGGTCGTCGGCCAGCAGCACCGAGTAGCCCGGGAGGAACTGCACGTCGCCGATGACGGCGAAGCCGGCGGTCAGCCGGCGCAGCACGGTGGGGTTCTCGCCGCGCAGGGCGCTGCCGACGCGGTCCGTCCGCCAGTCGTCGCTCATGGGCCGAACCTACCCCGCCGCCTCGCTCCGGGGGCCGAGCCGCCGGTCCAGAGCGGCGCCCACGACCGGGCAGTTGGCGCGGACGACGTCGAGGAAGGCGTCCAGGACGGGGGAGCGGTCCTCGGGGGAGAAGGAGAGCACCAGGTCCGGGAGCGGGGTGCGCGGGGTGACCTCGCAGAACCAGGTGCCCGGACGCGGGGCCGCCAGCATCCGGGAGGGTCCGAGGCCCACCCCGACCCCGCAGGCGGCGAGGCCGATGACGGTGTGCACGTCCCGGGCGACCGTCGCCGACGCGAGCGCCGGGGAGCCCTCGCCGAGCAGGTCGCGCAGCCCGGCCGCCACCGCCGGCTCGTCCTCGCCGGAGGCCAGGATCAGCGGCTGGTGGAGCAGTTGGGCCACCGCCACCGACCGCAGTCCCGCGTACGGATGGCCGGAGCCCACCACGGCGACCAGGTGGTCGTGGCCGACCGGGACCGACACCAGGCGTTCGGCGCCGATTCCGCGCGGCCGGCCGAGGGTGACGGCCACGTCCAGCTCCCCGCCGGCCAGGGCGGCGCTGCTGCGGCTGGACGCCATCTCGTGCAACTCCAGCCTCACTCCGGGCCGTTCCCGGCTGAACCGGCGCAGCACACCCGGCAGCGGGTCCAGCAGGGCCGAGGCGATGAAGCCCAGGCGCAGCCGGCCGCTCTCGCCGCGTGCCGCCCGGGCCGCGTCGACGGAGGCCGCGCCGATCTCCGCGAGCGCCGCCCGCGCCCGTACCAGGAAGGCCGCTCCCGCCGCCGTCGGGAAGACGCCCCGGCGGGTGCGGTCGAAGAGGCGGGCGCCCACCTCGCGTTCGAGGGCGGCGATCTGTTTCGACAGCGGTGGCTGCGCGATGCCCAGCGCGGTGGCCGCCCGCCCGAAGTGCGCGTGCTCGGCGAGGGCCACCGCGTACCGCAGGTGCCGTGCCTCCATCGTCCCCGTCCTTCCCCGCGACACCGTCCGGCGCGCGATACCCCCTGGGTATCGTCGGCGGGCCCGCGGGATCTTCCCGTGGCCGGGCGGGAGCGGGCCGCGTGGGATGGCGGGTATGAACGCCACCGCGCCCGTCGCCCTTCAACTCGCCCGCTCCCGTACCGCCTTCGTCCTCGTGCACGGGGCCTGGCACAGCTCCGCCCAGTGGGCCGCCACGCTCCAGGCGCTGGCCCGCCTCGGCGCCGCCGGCTACGCCGTCGACCTGCCGGGGCACGGGCTCGACGGACCGCTGCCCGGCGGCTACCTGCTGCCCGGCCAGCCGGGGCTGCTCACCGAGAGGTCCCCGCTCGCCTCCGTGACGATGGACGACTGTGCCGAAGCCGTCCTTCAGACCCTGCGCGCGGCCCGCCGGCACCACCGGGTCGTCCTGGTCGCCCACAGCGCGGGCGGCGGCCCGGCCGCGCTGGCCGCCGAGCGGGCGCCGGACCTCGTCGACGCCCTCGTCCACCTCTCCGCCTTCGTCCCCGCGGGCCGCCCCCGCTTCCTCGACTACATCGAGGCGCCCGAGAACGCCACCTCGCGCGGCCACTCCCTCTCCCTCGGCGACTCCGCCGCGCTCGGCGCCGTACGGATCAACCCGCTCTCGCCCGACCCCGCCTACGTGGAGGAACTCCGCCTCGCCTACTACCAGGACACCCCGCCCGGCCGCTTCGCCCGCTGGCGCGCCGCCCTCGGCACCGACCTGCCGCTGTCCGTGCCTACCACGCCGGTCACCCTCACCCCGGAACGCTGGGGGAGCATCCCGCGCACCTTCCTGCGCTGCGCGGAGGACCAGGCGCTCACCCCGGCGGTGCAGGACCTGATGATCGCGGAGACCGACCGGGCCATGCCCGGCCGCCGGTTCACGGTCCGGACCCTCCCCGGCGGCCACAGCCCGTTCGCCGCCCGGCCCGCCGAACTGGCGGCGGCCCTGCTGGCCTGAGCCTCAGGCCCCGGCCCCGTCGCGGGCGTACCGGGCCGGGGTCCGCCCGTACTCCTTGGCGAAGGCCGCCACGAAGGCCGACGGGCTGGCGTACCCCACCCGCCGGGCGATCCGGGTGACCGGCTCGGTGCCGAGCAGGGCGCGGGCGGCGCTCAGCCGCAGCAGGGTCCGCCAGCGGGTGTAGGACATGCCGAACTCCCGCTGGAAGTCGCGTTGCAGGGTCTTGGCGCTGATGTGCAGCTGGGCCGCCCACGCCGCCAGCTCCCGGGTGTCCGAGGGGTCGTGGGCCAGCGCGCGGGCCACCCGCAGCGCGTGCCCCGCACCGCGTCCCGAGGCCGGGGCGCCGGGCGGGCCGTCCCCGGCGAAGGAGTACGGCACCAGGGCCGCCATGATGCGCGCCCGGTCCGCCAGCGCGTCCGCCTCGGTCACCCCGGAACGGGCCAGCCCCCGGACGAGCCGCCCGGTCTCCTCCGGGACCACCACCGGGCCGGCGCGCAACTCCGCCAGGGCGGCCGGGACTTCACGCAGGCAGATCCGGTACACCGTCTGCCGGTCGGCGGCCCGCACCTCGTGGCTGACCGCCCGCTGCGCCCAGAACGCCTCACCGGGCCCCAGGAAGCGGGCCTCGGCTCCGTGCAGCGCCGACAGGGCACCGTCCGGCGACCAGTAGAGCTGGTGCAGGAAGTCCTGCCGGGCGATGGCGCCGAACTCCAGCGGCCCCGCCGACTGGTAGCGCAGCACGAAGATGCCCTCCGGGCGCCCCAGGCCGTAGCCGTACTCCTGGCAGCGCACGGGATCGTCCCCTCGTTGTCCCCCGAGCGACACAACGCGTCCTTTCAGCGACACATCCGGTAGATAAGTAAGGCTAACCTAACCACGTCGCCCTCGCGGGTGGCATCTCATCGCACCGAACGCCGAAGGAAACGCGCTCCATGTCCCCGACTTCCCCGCCGCCCGCCCCGACCCCCGCCACCGAGGCGCCCGGCGCCCGGCGCCGCCCGCGTTTCTTCCGCGCCCCGCTGCGGGCCGGCGCCCTCGGCCTCGCGCTCGCCCTGGGCCTCACCGCCTGCGGCACCGCCACCGAGGACAAGGCCGGCGACAAGCCGAAGACCCGGGTCTTCAAGGCCGACAACGGCGAGATCGAGATCCCGGCCGACCCGAAGCGCGTGGTCGCCACCGGGTACGCGGTGCCGGCCCTGATCGAGGCCGACGCGGCGCTGGTCGGCATCTCCACCTGGAAGCGCGGCCTGGACCTGATGACCGACAAGCACCTCGCCCGCTACGAGAAGGTCCCCAAGGTCGCCGGCGAGACCGCCGCCGAGACCAACTACGAGGCCATCGCCAAGGCCCGCCCCGACCTGATCGTGATCGGCGTGCCCACCCCCGTCCTCGCCGACATCGACGTGAAGCGGCTGGAGTCGGTCGCCCCGGTCGTCGCGATCGGCCCGACCCAGCCCGACGCCTGGCGCACCCTCTCCCGCCGCCAGTCCGACGCGGCCGGCCGCCTCGACCACTTCGAGGAGGCCAAGGAGGCGTACGAGAAGCGCGCCGGCGAGCTGCGCAAGAAGTACGCCAAGGTCCTGGACGGGCGGCGGTTCGGCCACGTCGGCGCCTACAGCGAGGCCGGGAAGGGCTCCTTCCAGCGCGAGTTCTCCCGCTCCTGGGGCACCAACATCGCCGAGGACATCGGCGTCACCTACTACGGCGAGGTGAAGAAGAAGACCGGCGGCAGCGGCGACGTCAGCGAGAACCCCTCCATCGAGCAGCTGCCCGAGAGCCTCGGCGACGCCGACGTCGTCACGTACACCGTGCAGCCCGACGGCGAACCGGCCGCCGCCGTGCAGTACGTGCTCGACTCCCCGCTGTGGAAGGAACTCCCCGCCGTCCGCGACGGGCTGACCGTGCCGCTGCGCTACACCGAGGCCGCGACCTACCCCTCCGCCCTGCGCACCCTGGACGCCCTCGACAAGGCGCTCCAGCCGCTCCTGGACCGGTGACCGGCATGACCACCGAACACTCCCACCCGCACCCCCGCGTCCGCCGGGGCGGACCCGACGACCCCACCGTCGACCGCTCCGACCCCGGTCCCAAGGTCGCCGAACACCACCGCGCGGGCACCGCCCTGGCCCGCATCCCCTACCCGATCGAGGTCCGCACCCTGGAGGTGCTGGCCCGCACCTGGATCAACCCGCGCATGGTCCGCCTGACCCTCGGCGGCCCCGGACTCGACGGCTTCCACACCCACCAGGCCGACGACCACGTCAAACTCGTCTTCCCCGACCCGGACGGCACCCTGCGCCCGCCGGTGCCCGCCCCCGGGGGCATGCTGACCTGGCCGCGCCCGAGCCCCCTCAGCCGCGTCTACACCGTGCGCCGGTACGACGCCGCCGCCCGCGAACTCGACCTGGACTTCGTGGTCCACGAGGGCGGGCACGCCTCCGGCTGGGCCGTCTCGGTGCCGCTGGGGGAGCGGATCACCGTGGCGGGACCGCCCGGCGCCAAGTCCTTCCCGCACACCTACGACCACTACCTCTTCGCCGTGGACGCCACCGCCCTGCCGGCTCTCGCCCGCTGGCTGGAGGAGAGCCCGCAGGACGTCTCCGCGCAGGTGGTGCTGGAGACCGACGAGGAGTGCGAGCACGCCTACCCGCTCGCCGAGCGCCCCGGCGTCGAGGTGATCCGCCTGACCCGTGCGGGCGGCCCGTCCCGGCTCGCCGGCACGGTACGCGGACTGCCCGCCCGCCCCGGCCGGAGCTTCCTCTTCGCCGCCGGCGAGTCCGGCGACATCAAGCCGCTGCGGGCCTGGAGCCAGGACCGCTGCGACGCCCTGTTCACCGGCTACTGGAAGCGCGGAGTGGCCGGACTTGAGGACTGAACCACCCCGCACCGCCCTGCTCTTCGGCGTCCTGGTGCTGCTCTTGGCCGCCGCCGTCGCCAGCCTCGCCGTCGGCACGCGCACCGTGCCGCCGGCCGAGGTCTGGCGCGCCCTCACCGACGCCCCGCCCGGCGGCGGCACCACCCTCGCCCACCACCTGGTGATCCGCGAGGTACGCCTGCCCCGCACGGTCATCGGCGTCCTGGTCGGCGCCGCCCTCGCCGTCTCCGGCGCGCTCATGCAGACCCTCACCCGCAACGCCCTCGCCGAACCGGGCGTGCTCGGAGTGACCGGCGGCGCCGGTTTCGCCGTCACCCTCGGCGCGGTCGCGGGCCTCGCCGGTTCGCAGGCCGCCCAGCTCGGCCTCGCCACCCTCGGCGCCCTGCTCGCGGCGCTCCTCGTGTACGCCGTGGGCCGCGCGTCCCCGCTGCGCCTGGTGCTGGCCGGGACCGCGCTCGGGTTCGTGCTCGCCGGGTTCTCGCTCGCCCTGCGCATGACGCTCCCCGACGTCTTCGACACGTACCGCTTCTGGGTGGTCGGTTCGCTCGCCGGGCGGGAGCAGGTGCCCTATCTGCTGCCGCTGCTGGTGATCGTCGCCGGACTGGCCGGGGCGCTGCTGGCCGCCCGGCCGCTCCAGGCGCTGGGGCTCGGCACCGAGGTGGCGCGCACCCTGGGCAGCCGGGTGCGGCGGACCCGGATCACCGTGCTGGTCCTCATCACGGTGCTGGCCGGGGCGGCGACCGCGCTGGCCGGGCCGATCGCCTTCCTCGGTCTGATGGTCCCGCACCTGGCCCGCCGCCTGGCGGGCGGCTCGGTCCGGCTGCTGCTGGGGCTCTGCATGGTGCTGGGCCCGCTGGTCCTGCTCACCGCCGACGTCGCGGCCCGGCTGCTGCTGCCCACCGGCGAGGTGCCGGTCGCCGTGGTCACCGCCTTCCTCGGCGGACCCGTACTCATCTGGGCCGTACGACGCTATGGGGCGGTGACGCTGTGAAGGTGGAGGAGAAGAGGGCGCGGGAGGACCGTGCCCCGGAGACGGGGAGTCGCGTCGTCGCCCGGCCCCCGCTGGCCGTCCGGATCGGGCGCTTCTCGGCCGCCGTCGAGCGGCGCGGCGCCGTCGCCGCCGTGGTCCTGGCCGCCGTCGCCGCCGTCCTCGCCTTCGTGGGGCTGTGCCGGGGGGACGCCTGGGACGCGCCCGGCGAGGTGTTCGCCGCGCTGGCCGGTCACGGTGACGCGGCCTTCGTGGTGCAGGAGTGGCGGCTGCCCCGGGTGACGGCGGCGCTGGCCTTCGGGGCCGCCCTCGGCGCCGCCGGAGCCGTCTTCCAGAACCTCACCCGCAACCCGCTGGGCAGCCCCGACGTGATCGGGCTCGACGCGGGCGCCTACACCGGCGCGCTGGTCGCCCTCACCGTGCTCTCCGGCACCAGCGTCCAACTGGCGGTCGGCTCGGTGGCCGGCGGGCTGGCCGCGGCCGTCGTCGTCTACCTGCTCTCGCTCGGCTCCGGCCTCGGCGGCCTGCGGCTGGTCGTCATCGGCATCGCCGTCAACGCCATGCTCACCGCGCTCAACTCCTGGATCGTGCTCCGCGCCGAACTGGAGGTCGCCATGGCCGCCGTCGGCTGGAGCGCCGGTTCGCTCAACGGCATCGGCTGGGAGGACCTGCGCCTGCCGCTGGCGATCCTCGCCGCCCTCGCCGTGCTGCTCGCGGCGCTGGCCCGCCCCATGCACCAGGTCGCGGTCGGCGACGACCTCGCCGTCACCTCCGGCGTCCGGCTCTCCGGCTACCGGCCGCTGGTGGTGCTCGCCGGAGTCGGCTGCACCGCGACCGTCACCGCGGTGGCGGGGCCGGTCGTCTTCATCGCCCTGGCCGCCCCGCAGATCGGCCGTCGCCTGGCCGGGGCGGCCGGCGTCCCGCTGCTCCCGGCCGCGCTGACCGGCGCGGTGCTCCTGCTGGTCGCCGACCTGACCGCGCAGACCGTCCTCGCCCCGGTGGCGCTGCCGGTCGGCGCCGTCACCACGGTCGTCGGCGGCGGCTACCTCCTCTGGCTCCTCGTCCGCGAGGTGCGCCGATGACCCCCGGCACCGGCCGCCCCGGCCTCGTACCACCACCGGCCCCCGCGCCGAGACCGAACCCCCGGAAAGAACCCACCGCCATGCCCCGCCTCACCGCCGACGCCCTCGAACTCGCCTACGGGGACCGGGTGGTCGCCCCGCGCCTCACCCTGGACATCCCGGACGGCGCCTTCACCGCCGTCGTGGGCGCCAACGCCTGCGGCAAGTCGACCCTGCTCAAGGCCCTCGTCCGGCTCCTGACCCCGAACTCCGGGACCGTCCGCTGGGACGGCGAGGACCTGCACGCCCTGCGCCCCAAGACGGTCGCCCGCCGGCTCGGCTTCCTCCCGCAGGGGCTGACCGCGCCGGAGAACACCCTGGTCCGCCAGCTCGTGGCCCGGGGCCGCTACCCGCACCAGTCGCTGCTGGCCACCTGGTCCCCGGCGGACGAACAGGCCGTCGCCGACGCGATGGCGGCCGCCGGCGTCGCCGAACTGGCCGAGCGGCGCGTGGAGGAGCTCTCCGGCGGCCAGCGCCAGCGGGTCTGGGTCGCCATGGTGCTGGCGCAGGAGACCCCGTACCTGCTCCTCGACGAGCCGACCACCTTCCTCGACCTCGCCCACCAGTACCAACTGCTGCGGCTGCTGGCCCGGTTGCGCGACGAGGGCCGTACGGTCGTCGCGGTCCTCCACGACCTCAACCAGGCGTGCCGCTTCGCCGACCACCTGGTGGCGATGCGCGGCGGCCGGGTGGTCGCCCAGGGCGCCCCCGCCGACATCGTCGACGCCGCTCTGGTCGAGGCCGTCTTCGACCTGGAGTGCGTGGTGGTCCCCGACCCGGTCACCGGGACGCCGATGGTGGTCCCGCACGCGTGAGGGCGGGGGCGTCTCACTAGGGTGGACGGGTGAACGCGCCCGGGCCGTCCGGTCTCCGGCGTGCGGGGACAGGGGGCACGAACCATGGCGAGGAACGAGCGTCGGGATAGCAGCGGCCCAGGAGCGCGACCGGGCCACGCACGCCGGGTCCCCTACACGGACCCGGGGGTACCGGACCACCGTACTCCGCTCAGGTTCCTGTGGTGGCTGACGACCAGCCAGCGCCGCCGCGTGCTGCTCGGGTCCCTCTGGGGCACCGCCTGGATGTGCCTGCTCATCGCCCCGCCCTACCTGATGTCCCGGGCGATCGACGACGGCCTGCGCGGCCGGGACCCCGGGGCGCTGCTCCTGTGGACCGGCGCGCTGCTCGCCACCGGCGCCGCCCTCGCCGTCCTCGGCATCCTGCGCCACCGCACCATGACCCGGGTCCGGGTGGACGCGGCCTACCGGACCGTGCAGGTGGTCACCCGCCACGTCACCCGCCTCGGCTCCGCCCTGCCCCGGCAGGTCTCCGCCGGGGAACTCACCCATCTCCAGGCGGGAGACATCGGCCGGATCGCCCAGACCCTTACCGTCACCGGCCCCGGCGTCGGCGCGGCCGCCGCCTACGCGGTCACCGCCGTCCTGCTCCTCGGGATCTCACCGCTGCTCGCCCTGGTCGTCCTGCTCGGCGTCCCCGCCCTCGCCCTGACGGTCGGCCCGCTGCTCGGCCGGCTCCACGGCGCCGAGGGCCGCTACCGCGAGGAGCAGGGGCAGCTGACCGCGCTCGCCGGTGACCTGGTGGCCGGGCTGGGCGTCCTCAACGGCATCGGCGGCAAACGGGTCTTCGCCGCCCGCCACCACGCCCGCTCCCAGGCCCTCGTCCCGCTCGGCTACCGCGTCGCCGCCCTCACCAGCTGGGTACAGGCCCTCACCGCCTGCCTCCTCGTCCTCTTCCTCGCCGTCGTCACCTGGATCGGCGCGCGCATGGCGGCCGCCGGCACCATCACCGTCGGCGAACTGGTGGCGGTCTACGGCTACGTCTCCGCGCTGCTGGTCCCCGTCTCGGCCTTCATCGAGGGCGCCGACGACCTGCCCCGCGGCCTCGTCTCCGCCCGCCGCGTCACCGACATCCTCGCCCTGGCCCCACCGCCCGCCACCGGCCGGCCCCGCCTCGACCCGCCGAAGACCCCGGCCGAGCTGTACGACCCCGACTCCGGCCTCACCGTCACCCCGGGCAGAGTCACCGCCCTGGTGGGCGTCCGGCCCGAGGAGACCCGCGCCGTCGCCGAACGCCTCGCCGGGCACGGCGCCTCCGCCGTCACCTGGGGCGGCACCCCCCTGGCCGCCTGGGACCGGGACGCCCTGCGGCGCCACCTCCTCCTCGCCGACCACGACGCCTACCTCTTCGCCGGCGACCTGCGCACCGCCCTCTCCGGCCGCGCCGACCGCCCCGGCGACACCGTCCGGGCCGCCCTCGACGCGGCGGCCGCCACCGACATCGCCGACGGTCTGCCCGACGGGCTCGACGGCCACCTCGACGACCAGGCACGCAACGTCTCCGGCGGCCAGCGCCAGCGCCTCAGGCTCGCCCGCGCCCTGCTCGCGGAGCCCGAGGTGCTCCTCCTGGTCGAACCGACCTCCGCCCTCGACGCGCACACCGAGGCGACGGTCGCCACCCGCCTCGCCGCCCACCGGCGCGGGCGGACGACCCTGGTCGTCACCACCTCGCCCCTCGTCCTCGCCCAGGCCGACGAGGTCGCCCACCTGGACGACGGCAAGGTCCGCGCCACCGGCACCCACGGCGAACTCCTCGCCACCCGGCCCGCCTACGCGGCCCTGGTCCTGCGGGGCACCGCCCGCGACGCCGCACTCCGGCCCCTGGAAGGGGACGCCCGATGAGCCGCCCCGCCCCCGCGCCGCGCCTGCCGGTCGCCGACGCCGCGACGGTCCGCCGGGCCGTCCGGCAGCTGGTCAGGGAGGACTCCCGCGCCGTGTGGGGCACCCTCGTACTGACGTGCCTCGCCGCCCTCGCGGCGGCGGCCGGCCCCTGGCTCCTCGGCCGGATCGTCGACCGGGTCCAGGCGGGCGGCCTGGCCGCCTCCGGCATCGACCTGCTGGCCGCGGCCGTACTGGGCTGCGCGGCGGCCCAGTTGCTGCTGACCCGCTGGGCCCGCGGCGTCTCCCACCGCTTCGGCGAACGCGCCCTGGCCCGCCTCCGCGAGGAGGTGGTCGAGCGGGCCCTCGCGCTGCCCGGCCGCGTCGCGGACAAGGCCGGCACCGGGGACCTCGTCACCCGGGCGACCCTCGACGTGGCGACCGTCGCGGCCACCCTGCGCTCGGCCGGGCCGGACATCTTCGTCGCCGTCGTCCAGGCCGTCTTCCTCTTCGGCGCGATCTTCCTCCTCTCCCCGCTCCTCGGCCTCTGCTCCCTGGTGGGGCTGCCGTTGATCGCGGGCGTGAGCCGCTGGTACCTGGCCCGCTCCCGGGAGGCGTACCTCGCCGAGGGTGCGGCGGCGGGCGAGGTCTCCGAGATCCTCAACTCCACGGCGCTGGGCGCCCGTACGGTCGAGGCGTACGGGCTCCAGGAGCGGCGCGGCCAAGTCCTCGACGAGGCCGTCGACACCACGTACCGGGCGGGTGAACGCACCCTCGCGCTGCGGTCGGTGCTCTTCCCGGTCACCGAGTTCGCGCACACCCTGCCGCTGGCGCTGATCCTGCTGGCCGGCGGGTTCGGGTACCTGGAGGGGGCGCTCTCGCTCGGCGCGGTGGTGGCCGGGGGGCTGTACATGTGGCAGCTGGTCGACCCGCTCGACCAGCTCCTCGTCTGGGTCGAACAACTCCAGCGCAGCGGCGCCTCGTTCGCCCGGATCAAGGGGGTCGGACTGGTCGCCCACCCGCAGGACACCCCGGTGGCGGCTCCCGACGGCGATCTCGTCGAGGTCACCGGCGTGGGCTACTCCTACCTCCCCGGCCAGGAGGTCCTGCACGACGTCACGCTGAGCGTGCGCCCAGGTGAACGGCTCGCCGTGGTGGGCCGTTCCGGCGCGGGCAAGTCCACCCTCGGCAAGCTGCTGGCCGGGGTGGACACCCCCGACAGCGGCAGCGTCCTGGTCGGCGGGGTCCCCGTCGCCGAGCTGGCCGCCGCCGGCGAGCTGGGCAGCCGCGTCGTCCTCCTCACCCAGGAGCACCACGTCTTCCTGGGCACCCTGCGCGAGAACATGACCATGGCCGCGCCGGGGGCCGACGACGCGGCGGTGCTCGCGGCGCTGGCCCTCGTCGAGGCGGAGTGGGTGGCCGGGCTGCCCGACGGCCTGGACACCCGGCTCGGCCCCGGCGGGCTCGTCCTCGAAGCGGCCCAGGCGCAGCAGCTCACCCTCGCCCGGGTGCAGCTGGCCGACCCGCACACGCTGATCCTGGACGAGGCGACCTCGCTGCTGGACCCGAGGACGGCGCGGCAGGCGGAGCGCGCCATGGCCGCCGTCCGCGCGGACCGTACCGTCATCGCCATCGCCCACCGCCTCCAGACCGCCCACGACGCCGACCGGGTCGCCGTCATGGAGGCGGGCCGCGTCGTGGAACTCGGCACCCACGAGGAGCTGGTGGCGGCCGGCGGCGTCTACGCGGGGCTGTGGCGCTCCTGGAACGGCGAGGGCTGAGACCGGGCCCCGCCACCACCCTCCCTACCGGTTCCAGCCATGGTCACGGGGGCTCGTGCACGGGGTCTGGACAGTGTGCGGTGCGCGTGCTGTCATGCCAACTGCCGTTCCTTCCAACGTTGTACAACCGCGTTGTCCCGGCCGGAACGGCGAGCCGCCACCTCCCCCCGAAGCGTTTTCCGCAGTTCACGCAAGGAGGACCCGTGCGCACCACCGGCCTCAGACGTCACGGACGTCACCTGGCACTGCTCCTGACCACGGCCCTGGCCCTCACGGCCTTCGGCGTCGCCCCCTCGGGCGCGGCGTCGGGCGACGACGAACCGGTCGCCGCCCACGGCCTCAAGGGCGAGTACTACACCCACTCCGCCGAGGGGGCCTTCGACTTCCACGAGCTGAAGGCCACCGTCTTCGATCCGGACATCGACTTCCCCAGCCTTGACGCCCGGCTCCAGTCCACGACCGGACAGGCGGACGACGTCAGCGTCCGCTGGACCGGCAAGCTGGTCCCGGAGAAGACCGGCGCGACGACGTTCTCCATGACCGGTGACAACGGCTTCCGGCTCTGGGTCGACGACGAGCTGGTCATCGACCACTGGGTCGACGACTGGGACAAGGAACAGATCTCCGACGAGGTCGAGCTGACCGCCGGTGAGGAGGTGGACATCAAGGTCGAGTACTTCGAGCACTTCGGCGGCTCCAGCCTCCGCCTGCGCTGGACCGAACCCGGCGGGCAGAAGGAGCCCGTCCCGTCGTCGGCGTTCCGGCTGCCCGACGACTGGGAGTACAACGGCGCCATCGGCTCCACCGTCCAGGCGGACGGCCGCACCCTGAAACTCGACTTCGCCCGGAAGCCGGGACCGCTCCCGGCCGGCCTGGAGAACCACCTCACCGCCGTCATCGGTGGCGCGAAATGGCCGCTGGACGGGGTGAAGCCCGACCCCGACGACCCGCGCGCCCTCCTCGTGGGCCTCGCGGAACCGGTCGTCGGCAACAAGAACGGCGACGCCCCCGGCAACGCCGACCTGACCTACGACGGCGAAGGCGGCCTCGTCCAGAGCGACGGCACGCCCGTCGACGCCTTCTGGACCAGCGGCGACAACCACTCCACGCACCAGCTGACCACCCGCTGGGGCGACGAGGTCACCCCGGCCAACGCCCACCGCGAGTACCCGCGCCCCCAGCTCACCCGTGGCGAGTGGCGCAACCTGAACGGCACCTGGCAGTTCGCCGGGGCCAAGGAGGGCGAGCGTCCGCCGGTCGGCAGGAAGCTCGGCGAAAAGATCCTCGTGCCGTACCCGGTCGAGTCGCAGCTCTCCGGCATCGAGCGGCACGAGGACCGCATGTGGTACCGCCGCACCTTCACCGTGCCCGCCGACTGGAAGATCGGCCAGCGCCAGCGGCTGCGGCTCAACTTCGGCGCCGTGGACTGGAAGTCCGAGGTCTACGTCAACGGGAAGAAGGTCGCCGGTCACGAGGGCGGCTACGACAAGTTCAGCGCCGACGTCACCGACGCCCTGAAGCCCGGCCGCACCCAGGAACTGATCGTCGGCGTCTACGACCCCACCGACGCCGACAGCGGCGAGAACCCGCCGATGGGCAAGCAGCGCCTGGACCCCAGCGGCATCTGGTACACCCCGTCCTCCGGCATCTGGCAGACCGTCTGGATGGAACCGGTCGCCGCCGACCACGTCGACGACCTCAAACTGACGCCCGACGTGGCGAAGGAACAGCTCACCGTCGAGACCGAGGGAGTCCGCGACGGCCTCCCCGTGAAGGCCGACGTCTACGCGGGCAAGCGGAAGATCGCCACCGCCACCGGCACCTCCGGCACTCCGCTCACCGTGAAGATCAAGAACCCGCACCTGTGGTCGCCCGACGACCCCTACCTGTACGACCTCAAGGTCAGTGTCGGGAAGGACAGGGTCGGCAGCTACTTCGGGATGCGCACGATCTCCGTCGAGAAGGTGAACGGCACCCCGCGCACCCTGCTCAACGGCGAGCCCGTCTTCCTCATGGCCACTCTCGACCAGGGCTTCTGGCCCGACGGCCTGCACACCGCGCCCAGTGACGAGGCCCTCGCCTACGACCTCAAGCTGCACAAGAAGCTGGGCTTCAACTCGGTCCGCAAGCACATCAAGGTCGAACCCGACCGCTGGTTCCACTGGGCCGACAAGCTCGGGCTGCTGGTCTGGCAGGACATGCCGTCCATGGAGGCGGGACGCAACCCCGGCCAGGCGGCGCGCGCCCAGTTCGAGCGCGAGATGAAGACCATGATCGACCAGCACCGCAACCACCCCTCGGTCGTCATGTGGGTCACCCTCAACGAGGGCTGGGGCCAGTACGACGAAGCCCGCCTCGCCGACCAGGCCAAGTCCTGGGACCCGAACCGCCTGGTCAACGCGATGTCCGGGATCAACCTCGGCGTCGACGGCGGTACCGGCGACATCCTCGACGAACACGGCTACCCCAGCCCCGCCCTGCCACCCGAGCCGGACGGCGAACGCGCCATGGTCACCGGCGAGTACGGCGGTCTCGGCCTCGCGGTCCCGGGCCACGCCTGGGCGGTGCAGCAGTCCTACGTCGACGTCGACCCGGCCACGTACACGGACGACTACCTCGAAAAGCTGGACGAGGTGCGCCAGTTGGCCTGCGAAGGCAGCAACGGTGCGGTCTACACGCAGATCTCCGACGTCGAGGGTGAGCTGAACGGCCTCGCGACGTACGACCGCAGGGTCGTCAAGCCGGACGTGAAGCGCGTGCACGACGCCCATCGGGCACTGATCCGCGACGCCTCGCAGGACACCGTGCCGAACTGCTCCTGACCGGCCCGCCGGCCGAGGGGACGGGCCCGCCCGCCGGACCCGCCCCCTCGCCGGCCCCCACAGGCAGGACTCTCCTCATGACACTGACACGCCGCACCGTGCTCCGGAGCAGTACGGCGGTGGCGGCCGCCGCCCTGGCCGGCGTCGGCGCCGGTACGGCCGAGGCCCGGCCCCGCCCGGCGCGCGCCGAAGGAGCCGTGGCCCCCGACGCCTTCACCCGGCTGCCCCCGGGCAGCATCACCGCGCACGGCTGGCTCGCCGGCCAGCTCAGGCTCCAGCTCGACGGCTTGTGCGGCCGGTTCGCGGAGACCTCCCACTTCCTCGCCATGGACACCTGCGGCTGGGTCCACCCGGAACTGGGCGCCTGGGAGGAACTGCCCTACTGGCTGCGCGGCTACGTCCCCCTCGCCATCGCCACCCAGGACGCCACCGCCCTCGCCACCTGCGAGCGCTGGATCGACGCCATCCTCGCGACCCAGGAGGCGGACGGGTTCTTCGGGCCGCGCGCCCTGCGCACCGGCCTCGACGACGGCCCCGACTTCTGGCCCTTCCTGCCGCTCCTGATGGCACTGCGCACCTGGCAGGAGTACACGGACGACACCCGCATCGTGCCGTTCCTCAGCCGCTTCCTGCGGTACATGGCGGACCAGGGGGAGAGCGCCTTCGACTCCAGCTGGGTCTCCGTGCGCTGGGGCGACGGCATCGACACGGCCCGCTGGCTCCACGACCGCACCGGCGACGCCTTCCTGGCCGGCCTCGTCGAGAAGATGCACCGCTTCGGCGCCGACTGGACCGGCACCGCCCTGCCCACCCCGCACAACGTCGACATCTCCCAGGGCTTCCGCGAACCCGCCCAGTACGCCCAGTGGACGACCGACGGCGCCGACGCCCTGACCCGCGCCACCTACCGCACCTACGACCAGGTCCTCGCCTCGCACGGCCAGTTCCCCGGCGGCGGTATCGCCGGCGACGAGAACCTGCGCCCCGGGTTCGGCGATCCCCGGCAGGGCTTCGAGAGCTGCGGCATCGTCGAGTTCATGGCCAGCCACGAACTGCTCACCCGCATCACCGGCGACCCGGTCTGGGCCGACCGCTGCGAGGAGCTGGCCTTCAACATGCTGCCCGCCGCCCTCGACCCGCAGGGCAAGGCCATCCACTACGTCACCAGCGCCAACGGCGTCCACCTCGACAACGTCCGCAAGTCCGACGGCCAGTTCCAGAACAGCTTCGCCATGCAGTCCTTCCGGGCCGGCGTCGACCAGTACCGCTGCTGCCCGCACAACTACGGCATGGGCTGGCCCTACTTCACCGAGGAACTCTGGCTCGCGGCCGACGGCGGCCTCGTCGCCGCGATGTACGCCGACTGCGAGGTGCGCGCCGAGGTCGGCGACGGGGTCGGCGCCACCGTCCGGGAGAGGACGGAGTACCCCTTCGACGAGACCGTCACCCTGACCATCGGCGTCGAGAGCCCCGTAGCGTTCCCGCTGCGTCTGCGCGTCCCCGGCTGGTGCGAAGCGCCCCGGCTGACGGTGAACGGGGAAGCCGTCCCCGTCTCCGGCGGACCCCGCTACGCCGAGATCCGCCGCACCTGGCACGACGGCGACGAGGTGGTGCTCCGGCTGCCCCAGCGCACCACCCTGCGCACCTGGTCCGGCAACCACGACAGCGTCAGCGTCGACCACGGCCCGCTGACGTACTCCCTGAGGATCGAGGAACGGTACGTCCGCACGGGCGGCAGCGACCCCTTCCCCGAGTACGACGTGCACGCCGCCTCCGCCTGGAACTACGGCCTGGTGCCGGACGGCTCGTTCACCCTCCACCGAGCGCGGGGCGCACGCGACGGCAACCCCTTCACCCTGGAGGGAACCCCCGTCACCCTCACCGCGCGGGCCCGCCGCATCCCCGAGTGGACCGCGGACCACGAACAGGTGGTGGCACCCCTCCAGCAGAGCCCCGCGCGCAGCCGCGCCGCCGTCGAGGAGGTGACCCTGGTGCCGATGGGAGCCGCCCGCCTGCGCATCACGGCGTTCCCCATGGCCGCCCCCACCGGCCACCCCTGGACACCCGAACCCCCTTACCACCGGATACTCAACAAGCACAGCGACAAGGTCCTGGCCGTGGACGGCATGTCGACCGCGAACGACGCCCGGGTCGTCCAGTTCGACAACGCCGGCACCGGCGACCACGCCTGGCAACTGCTGCCCGCACCCGGGGGAGCCCTGCGCCTGCGCAACGGCCAGAGCGGCAAGTACCTCGCGGTACGGGACAGTTCCACCGCCGACAGCGCCCTCGCCGTCCAGTACGAGGACACCGGCCGCCCCGACCTGCTCTGGACCCGCGAGGACCAGGGCGACGGCTGGTTCCTGCTCCGCAACGCCCACAGCGGCAAGGTCCTCGGCGTCCACGAGATGGCCACCGGGAACAGCGCCCAGGTCGTCCAGTACACGGACAACGGAACGGAGGACCACCTCTGGCGGCTGACGGACTGAGGGACTGACGGCGCCCGTGACTCCCCGCACGTCCATGTCGTTTTCCCGCCGGACCAGGCCCCCGCCTCGCTGCTTGACTGCGGTCATGACCACCGCTCACGCCGTTCACGCCGCTCACGTCCGCCTTTTCCGCTCCCTGCACACCCCCTCCGCCCCCTTGGCCCTCGCCAACGCCTGGGACGCCGCGAGCGCCCGCGTCGTCGAGGCCGCCGGCGCCCCGGCCGTCGCCACCACCAGCGCCGGGGTCGCATGGGCGCTGGGGAGCGTCGACGGCAACAGCCTCGACCGCGACCGCGCGCTGGCGGCCCTCGCCCAGGTGACCGCCGCCGTGACGGTCCCGGTCACCGCCGACCTGGAGGACGGCTACGGCGCCGGCCCCGCCGAGGTCGGCGCCACCGTCACCCGTGCCCTCGCGAGCGGCGTCGCGGGCATCAACCTGGAGGACGGCACCCGCACCCCGGCCGACTTCGCCGCCCGCCTCACCGCCGCCCGCACCGCCGCCGACAAGGCAGGCACCGACCTCTTCCTCAACGCCCGCATCGACACCTACCTGCTCGGCCTCGGCGCCCCCGAACACCGCCTCACCGAGACCCTGACCCGCGCCCACCACTACGTCGCCGCGGGCGCCGACGGCATCTTCGTCCCGGGCGTCACCGACCCGGCCACCATCAGCGCCCTGGCGGCGGAGATCCCCGTACCGCTCAACGTCATGGCGGGCCCGGGAGCGCCGTCCGTCGCGGAACTGGGCCGCCTGGGAGTGGCCCGGGTGAGCCTGGGGTCGGGGGTGGCTCAGACGGCTTACGGGGTGGCGGGGCGGGCGGCGCGGGAGTTGCTGGCCGGGGGGACGTACGACGCCCTGGCGGACGCGGTGCCGTATCCGGAGATGCAGGGGCTGCTGGCCGCGCGGTAGGAGGGGGCGGGGGAGGGTCAGGCCGGGTCGCCGCTCATCCTGCGCTGCAACTCCCACAAGGAGCGGAAGAGCCCGGGGGTGCGGGTGAGATCGGCGTAGGTGCCTTCCTGCACGATCCGGCCCTCGTCGAGGACGACGATCCTGTCGGCGACGGCCACGTTGGTGAGCCGGTGGGTGATCAGCAGGACCGCGCGGTCCTTGGCCAGTTCGCGCAGGCCGGAGAAGATCCGGTGCTCCGCCCGCGCGTCGAGGGCGGCGGTGGGCTCGTCCATCACCAGCAGCGCCGCCTGCCGGTGGAAGGCGCGGGTCAGGACGAGCCGTTGCCACTGGCCGCCGGAGAGCTGCTGCCCGCCGAACCACTCGCTGGTCAGCAGGGTGTTCAGGCCCGAGCGGAGGTGGGGCAGCATCTCGGAGGCGCCGGACGCCTCGCACGCGGCGAGCAGGGCCGCGTCGCCGGTGTCGCCCTGGCCGAAGGTGATGTTGTCCCGCATCGTCAGCGGCAGGTAGGTGAACTTCTGCGGCACCAGCGCGACATGCCCCCACGCCGCCCAGGGGTCGAGCTGTGCCGTGGAGGTGTGCCCCCAGGCGACCTCGCCCTCGGTGGGCAGCAGCAGTCCGCAGAGCAGACGCGAGAGGGTGGACTTGCCCGAGCCGTTCTCCCCGACCAGGGCCACGATCTCCCCGCGCCGCACGTGGAGGGAGACCCCGCTGAGGCTGTCCTTGGGGGCACCGTCGTAGCGGTAGGTGACGTTGCGGACCTCGAAGCGCTCCGGTACGGCCGACAGGAGCCGGCTGCCACGGGAGTCGGCCATGGCCTGGCCGTGGGCGTTGTCGAGGAAGTTCTGCCAGTCCTGGACGTACCAGCCGGTGCGGACCAGGCGGGCCCCGCCGTTGATCATGCCCCGCACGGAGCCGGTGGCCGTCTGGAGCGCGAAGACGGCGCCGCCGCCGGCCGCCAGGCTCATCCGCCCGGAGGAGAGGAGCCACAGCAGCGCCGCCCAGACGGCGGCCGAGGCGACCCCGCCGGCGAGCGCACCGGCCAGCCCCATCCGGGCCCCCGTGTTCGCCGCCTCGCGTTCGGCGGTGTTGACCGAGTCGGCCAGCTTCCGGTACCGGCCGATCAGGAACGGGCCGGCCAGGCAGGCCCGCATCTCCTCGCTCGACTCCTGGTAGGCCATGTGCCAGCGCAGCTTGCTCAGCATCCGGCGCCGCCCGGACGTGGCCACCTTCGCCAGGTACATCACCCGGGCCGAGCGGATGTAGGCGGCGGCCTGCGGCAGGCAGGCGAGCAGGAGCAGGGGGAGGAGCAGCGGGTGCAGGACGGCCAGGACGGCGGCGCCCGCCGTCAGCGTCGCGGCCGCCGCGAGCACGTCCTGCGCCTCCTCCACCAGGTCGGGGGTGACCTGGGCCCCGCGGTCGGCGATGTCGAAGGCGTCGTTGTAGCCGGGCTTGTTGTTGGCGGCCAGTTCGGCACCGAGTGCGGCCTCGACCATCGTCAGCTCCGCGGCCCGGGCGAGCACCGGCCGCAGCCGCCCGGTCAGCCAGACGACCGCGATGCCCAGCAGCGCCCGCAGGCCGGTGGCTCCGGCGATGACGGCCAGCTGCGGTGCCGCCTCCCACAGGCGCTCCGTGATGTCGCCCGAGGAGACCAGCGCGGTGATCGTGCCCGTGACGGCCAGCAGGCCGAGAGCGGCGAGGACGCCCGTGGCGATCTGGCAGACCAGCAGCCCGACGGTCGCGGCGCGGTCCACGCCCCAGGCCAGCCGCAGCGAGCGCAGGACGAGCGCCGGCAGGCGCCGCGCCATCGTCCGGGTGGTCAGGAGCGAACCGGCCTGGAGCCGCGACGCGTCCCGGTAGAGGAACTCCTCCTCTCGAACACCGGCTTCCTCCGGCACGGTGTCCTGCGGCGCTCCGGCCGGCCGTCCCGGCGGCTGTTCCTGTGTGACGGGCGAGGTCATCGGTCCCCCTGGGGTGGTGGCTGCGGCGGTGTCGTGGGGACCAACGACCTGGCGGGGATATCGAACACACCTCATTCGGCCGTGGTGCGGGGCCCGCCGACGGCGGGCGGCGGCGCACCGGGGCTCGTGTTCCCTGGTCCGCCCGGGAGCGGCCGCCGTCGCGGGGTGGCCGAAACGCCGGGCAGTGCCAGTGCCAGGGAGCCCGTGCGGCAGTTCTCAGTCCTTCGCCGCCTCCGTCGCGGCCCGCCCCAGCTCCTCTCGCAGCACATGCTTGGTGACCTTCCCCGAGGGGGTGCGGGGCAGCTCCGGGCGCAGGACCAGCTCGCGCGGGATCTTGTAGGGGGCGATGCGCGGCTCCAGCCACTCTCGGAGCGCCGCCAGCTCCGGTGCGGTGCCCTCGCGCGGGACGACGACGGCGACGACGGTCTCGCCCCACTGCGGATGCGGGCGGCCGACGACGGCCACGTCGAGGAGGTCCGGGTGGCCGCGCAGCGCGCCCTCCACCTCCTGGGAGGCGACGTTCTCACCGCCGGTGATGATGACGTCCTTCATACGGTCCACCACCGTGACGAAGCCGTCCTCGTCGACCCGGCCCAGGTCACCGCTGCGGTACCAGTCACCCGCGAAGGCCGCCGCGGTGGCGGCCTCGTCGTCGAGGTAGCCGACCATACGGGTGTCCGAGCGCAGCCAGATCTCGCCGGTCTCCCCGGCCCCGGCGTCCGCGCCGTCCGTCCGCACCACCCGCAGATCCACCCCGGGCATGCCGCCGCGCCCGATCGCCCCGGCCTTCGCGACCTGCTCGGCGGGGGAGAGCGAGGCGCCCACCGGCCCGGTCTCGCTCATCCCGTACACCTGGTGGAAGTTGTCCGAGCCGTACGCCTTCATCAGGCGGCGGGCCGTGTCGGCGTCCAGGGGGCCGGCGCCGTAGATCCAGGCGCGGACCGAGGTGAGGTCGAAGGCGGCGAGGTCGGGGACGGTCTGGAGCGGGGCGATGAGCGCGATCGGGGCGCCGAAGAGGGCGGTGATCCGCTCGCGCTGGATCGTCTCCAGCATGCCGCGCGGGTCGTACTCGCGCTGGAGGACGACGGTGGCGCCGAGCAACAGGGTGCTCATCGTCCAGTTGTTGAGCGGGGAGGCGTGCCAGATCGGCATGGAGATCAGGAACCGCTCGTCGCGGTGGAGGGGGATGGTGGCCGCCGTATAGGTGGCCGTGAGGGCGATCGAGCGGTGCGTGTGCACGCAGCCCTTGGGAGCGCCGGAGGTGCCCGAGGTGTAGAGGATCTGGGCGACGGTGTCGTCCGCGCCGGGCTCCTGCTCCGGCCACGGTTCGGCGAGCGCCAGCCGGGACTCGAAGGAGTCCCCGGGGCGGGACCACTCGTCGGCGTCGGGGTGGCTGACCAGCCACGGCACGTCCACCCCCGCCGAGGTCGCCCGCTCACCGATCTCCGCGTCGACCACCCCCAGCCGGGCGCCGCAGTGCCGCAGCAGGCGCTCCACCTCTGCGGTCCGCAGCTTGTGGTTGACCGGGACCAGCGTGGCCCCCGCGTACCAGGCGCCGAACGCCGCGAAGAGGAAGGCGGGCGTGTTGTACGTCATCACCGCCAGCCGGTCGCCGGGGCGCAGCCCGGCCTCGCGCAGCACCGTCGCCGCACGCCGGGCGCCGTCGGCGAACTCCCGGTACGTCCATCGCCGGTCGCCGTAGACGACCGCCTCCTTCTCACCGGCCGAGCGAACCGCGCTGTCCAGCAGGGCACTGAGGTGCATCACGTTCTCCTGACGAGCCACCGGCCGGCGGGAAGCGGCCGTAGCGGGAAAGTCTGAATGATGGTTCACTTCTTTCATGGCCTACCGCAAGACCCCTGCCGAAATCAGCCGGCTCGAAGCCGCCCGCGACCACCTCGTGGTCCGCGCCACCGAGGTCGTGGCGGAGGTGGGCTGGGCGCAGGCGTCCGTGACCGCCGTGGCGGACGCCGCCGGCATCGCGGCCGGCTCGGTCTACCAGCACTTCCCCTCCAAGGCGGCGCTCGCCGTCGAGGTCTTCCGGCGCGCGGCCGGACGCGAGGTGGAGGTGCTCGGCGAGGTGCTGCACGGCCCGGGCGACCCCGTCGGGCGCCTCGCCCGCGGCACCGAGGTCTTCGCCCGCCGCGCCCTGGAGAACCGGGGCCTGGCCTACGCGCTGCTCGCCGCCCCCGCCGAACCCGCCGTCGGCGCGGAACGCCTCGACTTCCGCCGCCGCTACCGCGCCCTCTTCGCCGCAGTGGTCCGCGAGGGGATCGCCGCGGGCGCCCTCCCGCCGCAGAACGCCGAGATCACCGCCGCCGCCCTGACCGGCGCCATCGGCGAGGTGCTCGTCGACCCGCTCGCCGCCCCCGACGAGAACGCCACCGAGGCGCTCCTCGCCGACCTCACCGGTACCGCCCTGCGCTGCGCGGGCGCCCCGGCCACCTGACCCACCCGTCACCGCTCCCGCTCCCGCCCCGCATCCCGCACCTGGAGGACGCCCCATGCACACCACCGGCTCCGTCACCCATGAAGTGACCAACCAGGCCCCGCCGCTGACCGGCCACGACGTCGCGGACGACCCGGTCCTGCTGGAGGGCGTGCGCCGCGAGGGAGCCGCGTGGCACCTGCCCGAGCTGCACCGCTTCGGCCGCTACGCGGGCAGCGAGGAGGCCCAGCACCGGGCCGACCAGGCCAACCGCCACGAGCCCGAACTGCGCACCCACGACCGCTACGGCCACCGCGTCGACGAGGTCGAGTTCCACCCCGCGTACCACGCCCTGATGGACGCCTCCGTGAGCGCCGGCCTCGCGGGCGCCGCCTGGGCCGACGAGCGGACCGGCGCCCACGTGGCCCGCGCCGCCGGCTTCATGGTGGCCACCACGGTCGAGCCGGGACACCTCTGCCCGGTCTCCATGACCTACGCCGTCGTCCCCGCCCTGCGCCACGCCCCCGACCTCGCCAAGACCTACGAACCTCTGCTCACCAGCCGCGTCTACGACCCCGGGCTGCGCACCCCCGCAGGCAAGCGCGGCCTGCTCGCCGGGATGGGGATGACGGAGAAGCAGGGCGGTACCGACGTCCGCGCCAACACCACCACCGCCACCGAACAGGGCGACGGGACCTGGCTGCTGCGCGGCCACAAGTGGTTCACCAGCGCCCCCATGAACGACCTGTTCCTGGTGCTGGCCCAGGCCCCGGGCGGACTCTCCTGCTTCCTGGTCCCGCGTGTCCTGCCCGACGGCAGCCGCAACACCTTCCGCATCCAGCGCCTCAAGGACAAGCTCGGCAACCGCTCCAACGCCAGCAGCGAGCCCGAGTTCGACGCCACCGTGGCCTGGCTCGTCGGCGACGAGGGCAAGGGCGTGCGGACCATCATCGAGATGGTGACGATGACCCGGCTCGACTGCGTCCTCGGCTCCGCCGCCGGCACCCGCGCCGCCCTCGTCCAGGCCGCCCACCACGCCCGCCACCGCTCGGTCTTCGGCGCCAAGCTGATCGACCAGCCGCTGATGCGCAACGTCCTGGCCGACCTCGCCCTGGAGTCCGAGGCCGCCACCACCCTCGCCCTCCGCCTGGCCGGCGCCGCCGACCGGGCCCGGCGCGACGACCCGGGGGAGCGCGCCTTCCTCCGCCTGGCCACCGCCGTCGGCAAGTACTGGGTCTGCAAGCGCCAGCCCGCCGCCGTCGCCGAGGCCCTGGAATGCCTCGGCGGCAACGGCTACGACGAGGCGTCCGGCATGCCGCGCCTCTACCGCGAGGCCCCCCTCAACGGCATCTGGGAGGGCTCGGGCAACGTCAACGCCCTGGACATGCTGCGCGCCCTGGCCCGCGAGCCGGAATCCCTGGAGGCGTTCCGCGCGGAGATCGAGGCGGTCTCCGGCGCCGACCGCCGCCTGGACACCGCCTGGCGCGAACTCCAGAGCCGGCTCACCCTCACCGAGGACGCCGAACTACGCGCCCGCCGCGTCATCGAACGCGCCGCCCTCGTCCTCCAGGCCTCCCTCCTGGTCCGCCACGCCCCCACCCCCGTGGCCGACGCCTTCTGCGCCTCCCGCCTCGCCGGCGACCGGGGCCTGGCCTTCGGGACCCTGGGGCCGGGGACGGACTTCTACGGGGTGCTGGGGCGGATCCCGGGGGAACCGGCCACGTCGTGACGGACCGTCTCAGCCCGTGCCGGGCTGGAGGAGCTTGAAGACCAGGCGCGCGGCGGAACGCCGCGCCGCCTGGCGCAGGCGCACAGGGCCCGGCACGGCGAGGGCGGGCGGCGGGGGAGTGGTGGCCAGGCGGGGGAAGAGCGCTTCGGCGTTGGCGCGGTCGACGGCCCGGCGCGTCTCCGGGGTGAGATGCTCGTCGAGACCGCTCGCGAAGTACTGCCCGGCGGGAGCGGGGGCGAAGGGCCAGTCGCTGCCGAAGAGGACGTGTCCGGGCCGGGCGAAGGCGAGCAGCGATGGCAGGGCGGCGGGGCTGGAGGAGAGGGCGGTGTCGAAGTAGAACGAGCGGAAGTCGTCCAGGACGTCGAGCGGGCTGCGCCCGGTGTCGTCGGCGATGGTGAGGGCCATGCGGTGGGAGGAGTAGGGGACGAAGCCGCCGGCGTGGCTGAGGATGAACCGGATGCCCGGGTAGCGGCGCGGAATGCCGTTGCGGACCAGGAGGTAGGCGGCGCGGGTGGTGTCCAGCAGGAAGTCGGCGGCGAAGGCGGGAATGCCGTCGACGGGGGGTGCGGGCAGTTCCGCCGGGTGGACGAAGACCACCGCACCTCGGTCGTCCAGCGTCCGCCACAGCGCGTCCAGGCCGTCGGCGCCCAGGTAGGTCCCCCGGTGGCTGGCGAGCAGGGTGACGCCGTCGGCGCGCAGGTCGTCCAGTGCCCGGACGGCCTCGGCGGCCGAGGCGTCGGTGCCGGGCATGGGCAGCGTGGCGAAGAAGCCGAAGCGGCCGGCGTGGTCGCCGGCCAGTGCTGCGGAGTGGTCGTTGAGCCGTCGGGCCAGGTCGGCGGCGTCAGCAGGTTCGGTGAGGAAGCTGGTGCCGGGCGTGGAGACGGAGACGATCGACGTGGCGGTGCCCAGCAGATCCATCAGCCGGAGGGCGGACTCGGGGCTCCAGGCGGGCAGCGCCCGTCCGCCGGCGTCGGTGATGCCCGCCTCGGCCAGCTCCTCGCGGTAGAAGGCGGGCACTATGTGCTGGTGCACGTCGATGCGGTGTGCGGAACGGGACATGGGGCGGCCTTTCCTGCGGTCTGCGGAGTACGCCGGGGACGACGAGGGAAGCGGCACCTACGCCCGCGCCGGGGGCGCCGTGCTCATGCCTCGCCCGGTGTCACCATGCGGGTCGCCGCGTCGTAGACCAGCTGGGCGTGCAGTTCGAGCATCGCCACCAGGTCGACCGCGTCGCCGTTGATCTCACGCTGGACGAACAGCCCGTCGGCGCCCGCGACGGCGTAGGTCGTCAGGATCCTGACGGACTCCTCGTCCAGGCCCGGGACCAGCGTCTGGGCCATCTCGGCGATCCTCGCGCACGCGATGTCGCGGACCTGGAGGAACACCGTGCGGCCGCGCGGTTCACAGGGGCGCCGCTCCAGCGCGAGCATCAGCCCCAGGCGGAGGAAGTCGGGGGCGTCGACCAGGGACTTCGCCACGTTCCCCGCCACGGCGGTGACCCGTTCGCGCGGAGTGCCCGTCTCCTCGCCCGGCAGCTCGAACGCGGCCAGCCAGGTGTCGAAGCTGCGCTCGATGACCGCCGCGATCAGGTCGTCCTTGTCCTTGAAGTGCCAGTAGATCGAGCTGGCGGGCAGTCCGCACGCGGCGCTGACGGCGGCGATCGAGGTGCCTTCGTATCCCCGTTCGCCGGCGATCTCCACGGCGGCGTCGAGGATGCGCTGCCGCGACTCCACGCCGTTCGCGCGCTTCTTGCGGGCCGTTCGAGGCTCCGTCATGGCGGTGCCCCCTCCTGTCGGTGCGGTGCGCGCCGGCCACTTGACCCTCCCCGGCGGCGAGCCTACCGTAGCACTCGTTCCAATTGGAGTGAACGCTACAGGAAGCTGTGCGGCGCATGATCGACAGTGAGGTGGCCCGATGAGTGAGACCGGGGCCGGTGCAGGGACCGAGGACGACGCCTACGACGTGGCGGTGATCGGGTACGGACCCACGGGCGTGACCGCGGCCAATCTGCTGGGGGCGATGGGGCTGCGCGTCGTCGTGGTGGAGCGGGACGCCGCGGTCTTCAGCCGTGCCCGGGCCATCTCCACCGACGAGGAGGTCGTCCGCATCTGGCAGCGGACCGGCCTGGCCGAGCGGCTCAAGCAGGACATGCTGACCGAGCGGGACGTGGACTTCGTCGACGCCGACGGCCGTTCGTTCCTCAGCGCCCGCCCCACGCCGCGCGGGCACGGCCACCCACCCCAGATGTTCATCTACCAGCCGGCGCTGGAACAGGTCCTGCGGGACGGCGTCGACCGCTACCCGAATGTGCGGATCCTGCTGCGCCACGAGTGCCTCCGCCTGCGCCAGGACGCCGACGGGGTGGAACTGACGGTCGTCGGCACGGCCGACGACTCCGTCCACCGGCTGCGCGCCTCGTACGTGATCGCGGCCGACGGCGGGTCCAGCCTCACCCGTGCCCAGCTGAACATCGGCTACGAGGGCACGACGTACGAGGACCGGTGGGTGGTGATCGACACGAAGATGCTCAAGCCCTGGCCGGACCACGACAAGCTGCGCTTCCACTGCGACCCGGCCCGTCCCGCCGTGGACTGCCCCACCCCGCTCGGCCACCACCGGTGGGAGTTCCCGATCCTGCCCGGCGACGACGAGCAGCAGCTGACCACCGACGACGCCGTGTACCGGCTGGTGGCCCGGTACGGGATCTCCCGCGACAGCATCGAGGTCCTGCGCGCCACCGTCTACAGCCACCACGTGCGCTTCGCCACCCGCTTCCGCGCGGGCCGGGTCTTCCTCGCCGGCGACGCCGCCCACGCCATGCCGCCGTGGATCGGTCAGGGCATGGCGGCCGGCGTGCGCGACGTGGCCAATCTGTGCTGGAAGCTGGACGCCGTGCTCCGTGGCGAACTGCCCGGGAGCGTCCTCGACAGCTACGAGGCCGAACGCAAGCCGCACGTCAAGGAGGTCACCAGACGGGCGGTCTTCGTCGGCCGGATCATCACCGAGCGCCGGCGGCCCGTCTCCCGCGTCCGCAACGGCCTCCTGCGCGCCCTGGACCGCGTACCGCGCTTCGGCGACCGCACGCAGGACTCGCACTGGATTCCCGTCGCCCGCTACGGAGCCGGCCTCCAGGCCCGCCCCCGCACCAAGGCCACCGGCCACCAGATCCCCCAGCCCTGGGTCACCGGCCCCGACGGCCTCCGCGTACGGCTCGACGACGCCCTCGGCGGCCGGTGGGTTCTGCTGCGCGCCGGGACCCCCACCCCCCAGCCCGCCTGGGACCTTCCTGGCGTATCTGCCCTGACCGTCACCCCCGCCGGCTCCCAGCCGGCCGCGGGCACCCTCGTGGACAGCGACGGCGTGCTGCTGCCCTGGATGACCCGGCACGGCGCGGCCACGCTCGCCCTGCGCCCCGACGCCTACGTCTACGCGGCGGCCCCGGCGGGCGCCGCGCTTCCGCCGCCGCCCCGCGGCTTCACCCCGCCCACGGCCGCGCCCCTCGACGCGACCACCGCCCAGTGAGGACACCGGCACCATGACGACGACACCGACCGGCCTGCCGACGATGCAGGAGACGACGTACGACATCGGCGGAAGGAAGATCTTCGCCGCGGAGACCGGGGACGGCCCGCCGGTCCTGCTGCTGCACGGCGGCGGCCCCGGAGCCTCCGGCGTCGCCAACTACGCCCGGAACGTCGCGCGGTTGGCCGGGGAGTACCGGGTGATCGTGCCCGACCTGCCGGGCTACGGCCGCAGCACCAAGGGCGTCGACGGCAGCGACCCCTTCGGCCACCTGGCCGACGGCATCCGTGGCCTGCTCGACCGGCTCGGCCTGGAGAAGGCCCACCTGGTCGGCAACTCCTACGGCGGCGCCTGTGCCCTGCGCCTGGCCCTGGACACCCCGGACCGGGTCGGGCGCATGGTCCTGATGGGTCCCGGCGGCATCGGCACCACCCGCGCCCTGCCCACGGCAGGACTCAACAGCCTGCTGAACTACTACACCGGCGACGGGCCCTCGCGGCAGAGGCTGGAGAAGTTCATCCGCAACCATCTCGTCTTCAACGCCGCCGACGTCCCGGACGCCGTGATCGACGAGCGCTACCAGGCCAGCGTCGACCCGGAAGTGATCGCCTCACCGCCGTTGCGACGGCCGTCCGGGCCCGACGCCCTGCGGACCCTGTGGAAGATGGACTTCACCCGCGACGCCCGCCTCTCCCGGCTGCCCGTGCCCACGCTGGTGCTGTGGGGGGCGCGGGACAGCGTCAACCGGCCGTCCGGCGGGCGGATGCTCGCCGAGCGCCTGCCCAACTGCGACCTGTACCTGGTCGCCAACACCGGCCACTGGGTCCAGTTCGAACGCGCGCAGCTCTTCAACCAGCTGTGCGCCGACTTCCTGGCGGGCCGCCGGTGAACACCGAAGCGCCCCGCACCGGCTCCGTCTTCGGCGCCGTCCACCTCGGCTACCTCGTCATCGAGACCAACCGCTTCGCCGACTGGCGCCGCTTCGGCACCGACGCCATCGGCATGCACCACGACGCCCTCTCCCGCGACCTGATGCGCTTCCGCCTCGACGACCAGGAATGCCGTTTCCTGCTCCGGCGCGGACCGGCCGAGGACGTCGTCGCCACCGGCTGGCACATCGACGACCACGCCTCCTTCGAGCAGATCGAGGCCCGCGTACGGGCCCACGGCGTCCCTGTCGTACGGGGATCCGACGAGGAGGCCGCCCTGCGCGGCGTGGAACGCCTGCTGCGCTTCCCCGGCCCCAAGGGCATCACCCAGGAGATCTACACCACCCCGGTGACCTCGGCCGAACCGCTGCGCATGCTCGCCTCCGGCTTCGTGACCGGCGACTCCGGCATGGGACACATCGCGCTGACCTCCACCAGGCCCACGCGGATCCGCGGCTACTTCGACACCGTCTTCGACGCCCGCCTGACCGACTACATCGACGAGACCATCAGCGGCGTCAAACTCAAGATCCGCTTCCTGCGCGTCAACGAACGCCACCACTCCATCGCCGTGGCCGCCACCCGAGGGCTGCCCATCGACCCCGTCCGAACCCGCGTCCAGCACCTCAACATCCAGGCCGCCACCCTCGACGACCTCGCCCAGAGCTACCAGCGCGTGCACGAACTCGGCTTCGACATGGCGCTGTCGGTCGGCCGGCACACCAACGACAAGGAACTGTCGTACTACGCCCGTACTCCCTCGGGGTTCGAGTGGGAGGTCGGCTGGAACCCGATCGTCATCGACGAGACGACCTGGGAACCCGCCACCCACCAGGGCATCAGCACCTGGGGTCACCTTCCCGTCGGCCAGACCGTCGTGGACAGGCTCGCCCAGTTCCGCGCGGCCGCCCGCTCCCTGGCGCACCCCGAGGACACGGTGCCCGCCCTCAGCGGTCCGGGGATCGCCGACGACTGACCCGGTACGGACACGCTCCACGGGCGGGCCGGGGAAATGTACCGTGACCCACGGCAACAGGTCCGGCGGTGCCGGAGCGACGCGGGGTCCGCGGGTGACCCTGGTGATGTGAGGTCTCATGACAGATGAGAGGGTCGGGCGCGTGAGTGAGACACCAGCGAACACCCTTCAGTACCGCTTCGACGGGCCGGAAGACGCCCCCGTTCTCGTCCTGGGTCCCTCACTGGGGACGACCTGGCACATGTGGGACCGCCAGGTTCCCGAACTGGCGCGCAGCTGGCGGGTGTTCCGGTTCGATCTGCCGGGGCACGGCGGGGCGCCGGCTCATCCGGCCGGGTCGGTCGCCGAGTTGGCCGACCGGGTGCTCGCCGCGCTGGACGCCGCCGGGGTGCAGCGGTTCGGGTACGCCGGGTGTGCGCTCGGCGGGGCCGTGGGGGCGGAGCTGGCGCTGCGGCACCCCGGGCGGGTCGCCTCGCTGGCGCTGATCGCCGCCTCCCCGCGGTTCGGGACCGCCGACGAGTTCCGCCAGCGCGGAGTGGTGGTCCGGTCGCACGGGCTGGACCCGGTGGCGCGGGCCGCCCCCGAGCGGTGGTTCACGCCGGGGTTCGCCGGGGCGCAGCCCGCCATCACCGAGTGGGCGGTGCAGATGGTGCGCACCACCGACCCCGGCTGCTACATCGCCGCCTGCGAGGCGCTGGCCTCCTTCGACATCCGCCCCGAACTGGGGCGGATCGGGGTGCCGACCCTCGTCCTGGTCGGCTCCGAGGACCAGGTCACCGGGCCCGCCGAGGCGCGCACCCTGGTCGCCGGCATACCGGACGCCCGCCTCGCCGTGGTGCCCGGTGCCTCGCACCTGGCGCCGGTGGAGCAGCCGGCCGCCGTCACCGACCTGCTGGTGCGGCACTTCTCCGCGCCCTGGAGCCCCGCCCCGGAGGCGACCGGCCAGATCCTCTCGCCGGTTCCGGCGCCGGTGGTCGTGCCGCCGCAGCCCACGGGCCCGGTCGCCGAGATCGCCCCCTGGGTCGACCCCGACGCCGCCGTGCGGCCCGACCCGTACGAGTCGGGTATCAAGGTGCGCCGGGAGGTGCTGGGCGACGCCCATGTCGACCGTGAACTGGCCGAGGCCGACGGCTTCTCGGGCGAGTTCCAGGACTTCCTCACCCGGTACGCGTGGGGCGAGATCTGGAGCAGGCCCGGTCTGGACCGCCGTACCCGTTCCTGTGTCGCGCTGACCGCGCTGATCGCCTCCGGGCACACGGCCGAACTGCCCGCGCAGGTACGGGCGGCGCTCCGCAACGGCCTCACCGTCGCGGAACTCCGCGAGGTCCTGCTCCAGGCCGCCGTCTACTGCGGGGTCCCGGCTGCCGAGGAGGCGTTCCGGGTCGCCCGCGCGGTGGTCGCCGAGGAGACGACGCCGCAGGAGTAGGCGGCGGGCCCGGGGCCCGGGTCACAGGCCCGGGCGCTCCACACCCCCGCACCAGACCGCCCGGACGCGGGCCGTCGCCGTGATGTCGGCCAGCGGGTCGCCGTCGACCAGCACCAGGTCGGCCCGCAGCCCCGGGGCGACGGCGCCGCGGTCGGTCAGGCCGAAGTGGCGGGCGGGGAGGACGGTGGCGGCGCGCAGGGCGTCGAGCGGGGTGAGGCCCGCGTCGACCAGCAGGGCCAGTTCGTGGTGGAGGCTCGGGCCGTGCGGGACGGAGGCCGGGGCGCCGGGCGCGTTGTTGGCGTCGGTCCCGGCGAGGATCGGCACCCCGGCGGCGTGCAGGGCGGCGACGCCCGCCCGCGCGTGGGCGTAGTCGAGCCCCAGGTGGCCGAGGGCCTCGGCGACGGCCTCCATCATGGCGAGCGTCGGAACCACGAACCGGCCCTCGGCGGCCGTCAGTTCGGCCTCGGCGGCGGGCAGCTCCGCGTCCAGCGGCACATGGGTGACCGCGTCCACCCCGGCCCGGCGGGCGGCGGCGAAGGCGGCCACGGCGGAGGCGTGGGCGACCGTGCGCAGCCCCCGCTCGCGGGCGGCGCGGACCACGGCCTCCAGCGTCTCCTGGGAGAGCGCCCCGGGCGTGCCCGGCACCTCCGCGATGATCTTGACGTAGTCCACGCCCTGCTCGGCCCGCTCGGCGACGAAGGCCGGCGCGTCCCCGGGCCAGGCGAGCAGGCTGCTCCGAGGGAAGTGCGGCATGCGCGACTGGACGCTGCCGGGCGCGGCGGCCGGGGCCCCGGCGCGCAGCAGGGCGGTGGTGCCCGGCAGGCCGCGCAGCGAGTCGAGGAGGGCCGGGGGCCAGCCGCCCATGTCCAGGGCGGTGGTCACGCCGTGGTCGGCGAGCCGGTCCAGGGTCCCGGCGTCGCGGACGTGCACATGGGCGTCGATCAGGCCGGGGAGCAGGGTGGCGCCCCGGCAGTCCACGACCCGGGCGCCGGCCGGGTCGGTGCCGATCAGCGGCCCGTTGATCACCACGGTCCCCGGCTCCCGCAGGCGCTCACCGTCGAAGACGCGGACGTGGGTCAGGGCCGTGGCGGTGCTCGCGGTCATACGGGGGCTCCATCCGGGTGCGCGGGTGCGCGGGTGCGCGGGTGCGCGGCCGGGCGGGCCTGGCTCTCTCCGCGCCTCAAGAGACGAAGTTGTTCACTGAGACCCTAACGCGGCCCCGTGCCCTCCGACCCCGCCCCGTGCCGCTATACAGAAGCCATGACCTCCGCCCCGGACCCCCAGGCCCCGGACGCCGCGCCGAGCGGCCGGCCGCCCCGCCGCCACGGCGCCGACCTGACGCGGGCGATCCAACTGGCGACCCTGGCCGAGCTGGCCGACACGAGCCTGGAGGAGCTGAGCTTCGAGCGGATCGCGGCCCGCGCCGGTGCCGGCAAGGCCTCGCTCTACCGCCGCTGGAGCACCCCGGCCGGACTGCTCCTCGAAGCCCTCGCCGACCCCGTCTCCGGCTTCGGCGACCCCCCGCCCCAGCCCCGCACCGGATCGCTGCGCACCGACCTCGTCCGGCTGCTCGGCGCCTTCGCCGACGCCCTGGACCGCCCGCACGGCCGCGCCCTGCGCCCGCTGCTCGCCCAGCGCGCCCGCCACCCCGAGCTGTACGCGGAGGTGTACCGGCGGGTCGTCCTGCCCCACAAGGAGATCCTGCTGGGCGTCCTGGGCGCTGCCGTCGAGCGCGGCGAGGCCGGCCCCGGGGCCCTCGGCGTCCGGACCGCCGCCACCGCGCCCCGCCTGGTGATCGCGGCCCACATGGAGCACGGCACGGTCCCGCGGGACGAGGTGGAGGCGCTCGTCGACGAGGTGCTGATGCCGCTCTTCACGGCCGGGGGAGGGGGGAACGTGCCGGGCCCGGAGGAGAGGAGCACGATGGGAGCATGAGGTTCATCAAGAAGCGCCATTCCTGTGTCCGGCTGGAGAAGGAGTCGGGCACGCTCGTCATCGACCCGGGCGGTTTCACCGAGCCCGACGCGGCCCTCGGCGCCGACGCCCTGCTGGTCACCCACGAGCACCCGGACCACTTCGACGAGGGCCGCCTGCGCGCCGCCCTGGAGGCCAATCCGGCGGCCCAGCTGTGGACCCTCGCCTCGGTGGCCGGGCCCATGGCCGCCGCCTTCCCCGGCCGGGTCCACACCGTCGGCCACGGCGACACCTTCACCGCCGCCGGGTTCGACGTCGAGGTCCACGGCGAGCTGCACGCCGTCATCCACCCGGACATCCCGCGCGTCACCAACGTCGGCTACCTGGTCGACGGCGAGGTCTTCCACCCCGGCGACGCGCTGACCGTCCCCGACCGGCCCGTGGAAACCCTGCTGCTGCCCGTCATGGCCCCCTGGAACAAGCTCTCCGAGGTCGTCGACTACGTCCGCGAGGTCCGCCCGACGCGCGCCTACGACATCCACGACGCCCTCCTCACCGACCTGGCCCTCCCGGTCTACGAGCGGCAGATCGGCGCGCTGGCCGGCACCGACCACCACCACCTGGGCCCCGGCACGTTCACCGAGGTCTGACGGGCGTTGTCGGCGGGGTCGGTTAGGTTGTCAGGCATGCGCATCGCCACCTGGAACGTCAACTCGATCACCGCGCGCCTCCCGAGGCTGCTGGCCTGGCTGGAGAGCAGCGGCACGGACGTGCTGTGCATCCAGGAGACCAAGACCACCGAGGAAGCCTTCCCCGCCGACGCCCTCGCCGAGCTGGGATACGAGAGCGCGGTCCGCGCCACCGGCCGGTGGAACGGCGTCGCGATCGTCTCCCGCACGGGCCTCGCCGACGTCGTCGGCGGCCTGCCCGGCGGCCCCGAGTACGACGGCGTGGAGGAGCCCCGGGCGATCTCCGCCACCTGCGGCCCGGTCCGCGTCTGGTCGGTCTACGTGCCGAACGGCCGCGAGGTCGGCCACCCCCACTTCGCCTACAAGCTCCAGTGGCTCAAGGCCCTGCGGGACGCCGTCGCCGACGACGCGGCGGGCGGTCGCCCCTTCGCCGTCCTCGGCGACTACAACATCGCCCCCCACGACACCGACGTCTGGGACCCCACCGCCTTCATCGGCGCCACCCACGTCACCCCCGAGGAGCGCGAGGCCCTCGCCGCCCTGCGCGCCACGGGGCTGGACGACGTGGTCCCGCGCCCCCTCAAGTACGACCAGCCGTTCACCTACTGGGACTACCGCCAGCTCGGCTTCCCCAAGAACCGCGGCATGCGCATCGACCTCGTCTACGGCAACGACCCGTTCCGCGCGGCCGTCTCCGACGCCTACGTCGACCGCGAGGAGCGCAAGGGCAAGGGCGCCTCCGACCACGCCCCCGTCGTCACCGACCTCACCGTCTGAGCCGCCGGGGCGCTCACCGCGTGCGCCCCCGCCGCCCGTCCAGCACGGTCAGGTCGACGGCGTCGGCCAGCGCCTGGAGCCCCGCCTCGCCCGGGTGCAGGTGGTCGCCGCTGTCGTAGGCGGGGAGCATCCGCGCCGGGCGGTCGGGGTCGCGCAGGACGCGGTCGAAGTCGAGGACGGCGTCGAAGGAGTCCCGGTCGGCGCGGAGCGCCCGGTTGATCTCGGTCCGCTCGGCGTCGACGGCGGGGGTGCACCGCGACTCGCCCTCGCACGGCGCGAGCGTGGTCACCACCGCCCGTACACCCCGGGCGCGCGCCCGTTCGGCCAGCTGCCGCAGCCCGTCGACGACCTCGTCGGCGCGCGCACCCCACCGGACGTCGTTTATACCCTCGAAGAGGACGACGGTCCGCACCGAGGTCTGGGAGAGCAGGTCCCGGTCCAGCCGGTGGAGGGCGCTGACGCCGCCGGTGTCGCTGGAGACGCCGTCGCCCGGATAGCGGTCGCTGAGCACGCGGTTGGCGGAGATGCCCTGGTTGAGCACGCCGTAGCGCGGCACGCGGTCCTGGTCGCGCAGCCGCCGGGCGAGCGCGTCGGTCCACCGCTTGTTGGCGCCCTCGGTGGTGCCGACCCCCTCGGTGATGGAGTCCCCGAGCACCACCACCGACCCCGGCCCGCCGCTCACGTCGACCCCGGTCAGCAGCGGCCAGGTCCCCACCGTCCCGGTGTACGCGGCGCCGTCGGCGTCGGCCGCGTGGTCGCCCGGGGTGCTCAGGTACGACTTCTGCACCGCCTTGTCGTGCAGCGGGACGGAGGGCACGGCGCCCGGCAGATGCAGGCTCACCAGCAGATCGGCGCCCTCCTCCACGGCCAGTCCGACCGGGTCGCTGACCGCCTCGGCCCCGGCGGGCAGCACCGTCGACTCCTGCCCGCCGAAGGTCAGCGGCACGGGCGTCGACCGGGGTTCCGCGCCCTCGGCGCGGACGGCCACGGTGGCGCTGCCCACCCGCACCGGCGTCCCCGCGAAGGTGTTGGAGAGCCGCACCCGCGCCGTCGGCCCGGACTTGGTGGGGTTGACCACCAGCCGCAGCGTCTGGTCACGCCACGGCCCGACCTCCGGCAGCCCCGCGGTCGACGCCGACCAGCTCCCCGTCCAGCCCTCCGCCGCCGGACGGACCCGCAGGTCGAAGACGTGGAGCGAGCGGCCCAGCCCCCGCACGTGCGGCAGCCGCACCGACTCCACGGTGCGGCCCGCGTCAAGCGGCACCGTCACCACGTACAGCCGGGGGCGGTCCGCGACGCGGCCCTCGCGGCTGTTGAGGTACGGCAGGGCGACGGCCTTGGTGGCGAGTGGGCCGGTGCGCCAGTCGGGGGCGGTCAGCCGGTAGCGGCTGTGGCCGCCGTCGCGGTAGTGGACGGTGCCGACGCCGGTCGCCTCGCCGCCCGTTCCGGCGACCAGGAAGGTGAGCGCGTCTCCGCGCCCCTCGACGGCCACCCGCTGCCCGTGGGCGCGCACGTTGTCGGGTCTGCCGGGTCTGGAGACCGGCCAGTCGAGCCGGGTGCCCTCCACGGCGGGGCGGGCGCCGATCTGCCAGCCGGCGGCGCGCAGCGCGGCGGCCGGCAGGGAGCGGCCCTGCCCGTCGAAGTCGGCGGCGCCCGGCCGGCCGTCCTCGCTGACCGCCCGGTTGTCGTACAGCTCGCGCAGCGGCCGCGGCTCCTGTTCCTCGGCCGCGCCCGCCGAGGTCAGCGAGGCCGCGCTGGTGATCAGGGCCAGAACGAGGGCGGGCCCCCACAGCTGTCGGCGCACGGGCGCCCCCTTCTTCGGTCGTCGTCCTCGGTCGTCCTGGCGGGCCGCACGACCGACGCGTCGAGGCCCGCCGCCGACTCGATGGTGCCGGTCGGCGGGGCCGGTGCCGTGGTGCCGGAGGTCTTCGGTGCGTCGGGCGGGGCGGCGGAAGGTCCGGACCACGGTAGGAACGCCGCTGAGGGAGCGTCAACGGCGCCTCGGCCGACGGGACGTGAACAGGCACCGAACAGGCCATGTCCGGTTCCGGGCCGCGCGCCTGTGGCCTCCCGGCGTCCGGCGGTGCCACGCTGGACGGCATGCACATCCCCTTCCTGGACAAGTGGCGCGAACGGCAGAGCGGACCGGGACGCTCGGCCGCCGCCGTCTTCGAGGACCACCCGGACGCCGCCGCCGACCTCTTCGCCGAGTGCGAACTGCTGCGCTCGCACGCGCAGGTGGCCGGGCTGGAGCTGGACGACACCCCGGCCTCGCTGGCCGCCCTCGACCAGTTGCTGCCGCGCTGGCGCGACGACCCCGAGGTGCTGCCCTGGCTCGGCAACGACGCCGGGCTGTACCTGGGCACCGTCGTGGTGCGGACCGTGCCCGGCGCCCGCTGGCACGTCTGGCCGGGCGGCCGTGTGGTGGTCCGGCTGCCCTCCGGCCGCGAACTGCACGTCGTCGAGGCCGGTGTCGAGTGGGCCGTGCACGGCGCGCCCGAGCTGTCCCAGATGTACGCCGAGATCTCCGAGGGCTGACCTCCCGCCGCCCCGGCCGCGCCCGCCGGTACCGCCGGCCGGCGGTGCGAGGATGGGCAAATACGGTTAATCCCGCCCTGTGCGTGTCGTTTGTCCGGCCCTGAGAGGCGCTGGATAGTTTGCGCGGACCGACACCGCTGGAAGTGGGTAGAGCTGGGCATGGCTGTCGATCCGTTGATCGAGTTGCACGACGTGAACAAGTACTACGGCGACCTGCACGTCCTGAAGGACATCAACCTCACCGTCGGCCGCGGAGAGGTCGTCGTCGTCATCGGCCCCTCGGGGTCGGGAAAGTCCACCCTCTGCCGCACCGTCAACCGGCTGGAGACCATCCAGTCCGGCACCATCCGGCTGGACGGGCAGCCGCTGCCGGAGGAGGGCAAGGCGCTCGCCGGGCTCCGCGCCGAGGTGGGCATGGTCTTCCAGGCGTTCAACCTCTTCGCCCACAAGACGGTGCTCCAGAACGTCTCGCTGGCCCAGATGAAGGTCCGCTCCCGCAAACGGCCCGAGGCCGACCGGCGCTCGCGTGAACTCCTGGAGCGCGTCGGCCTCGCCGAGCACGCCGACAAGCTCCCCGCCCAGCTCTCCGGCGGGCAGCAGCAGCGGGTGGCCATCGCCCGCGCGCTGGCGATGGACCCCAAGGCGCTCCTCTTCGACGAGCCGACCTCCGCGCTCGACCCGGAGATGATCACCGAGGTGCTGGAGGTGATGCAGCAGCTCGCCCGGGAGGGGATGACCATGGTGGTCGTCACCCACGAGATGGGGTTCGCCCGTTCCGCCGCCAACCGGGTCGTCTTCATGGACGGCGGGCGGATCGTCGAGGACCGCACCCCCGAGGACTTCTTCAGCAACCCGGAGAGCGACCGGGCCAAGGACTTCCTCTCCAAGATCCTCAAGCACTGAGGGGGCGACGCCATGACGCACACCGATCCCCACCGCCGGCCCGGCCGCGCCGTCCGCCTGCCGGCCCTCGCGCTGCTGGTCCTCCTCGCGCTGGTCGCCGCCTGCGGCAAGGAGGGCAGCCCGCCGGTCAAGGGCCCCCGCGCCGACCAGCTCCCCGACTACCGCGTGGACACCGGCTTCAGCCTCCCCGAGTCACCGACCTGGCGTAAGGCCAAGGCCCGCGGCGCCCTGATCGTCGGCGCCAAGGAGGACCAGCCGTACCTGGGCGAGAAGGACCCGGCCGGCGGCGGTTACACCGGCTTCGACATCGAGATCGCCAAGATGGTCGGCGCCCACCTCGGCTTCGCCGAGAACCGCGTCCGCTTCACCACCATCGCCTCCGCCAACCGCGAGACCGCCCTCCAGAACGGCCAGATCGACTACTACGTGGGCACCTACACCATCAACGACAACCGCAAGCGGCTCGTCGGGTTCGCCGGTCCCTACTACGTCGCCGGGCAGGGCCTGCTGGTCCGCACCGACGAGGAGGACATCAAGGGGCCCGAGGACCTCGACGGCAAGCGCGTCTGCTCCGCCGCCGGCTCCACGCCGTACCAGCGGATGCAGGAGGAGTACCCGAAGGCCGTGCTCGTCTCCTACGACACCTACTCGATCTGCGTGGACAACCTGCTGACCTACCAGGTCGACGCCGTCACCACCGACGACGCCATCCTGCTGGGCTACGCCGCCAAGGTCCCCGAGGAACTGAAGGTCGTCGGCAAGCCCTTCTCCGAGGAGCCGTACGGCATCGGGGTGCTGCGCTCGGACAACGCGCTGCGCCTCGCCATCGACGACGCCCTGGAGGAGGGGGAGCGCAAGGGCTACTGGAAGGCGGCGTACGACGCGACGCTCGGCCTCTCCGGAGTCCCCGCGCCGAAGCCGCCCGCCATCGACCGCTACGCGGCCGGCTGAGGAGGGGAGCGCCCGTGAACGTCCTGACCGACAACTTCTCCACCTACGGCAAAGGGTTCCTCGGCACCGTCGAACTCACCGTCTACGCCTCGCTGCTGGCCCTCGTCCTCGGCTTCCTGATGGCCTCCTTCCGGGTGGCGCCCGTCGCCTCGCTGCGCTTCTTCGGCACGGCCTGGGTCACCGTGCTGCGCAACACCCCGCTGACCCTGCTGTTCTTCGCCGTCCTGCTCGGCCTGCCGCGCTTCGGCCTCGTCCTGCCCTTCCAGCTCTTCGCGGTGCTGGCGCTGGGGTGCTACACCTCGGCCTTCATCTGCGAGGCGCTGCGCTCGGGCATCAACACCGTGCCGCGCGGCCAGGGCGAGGCGGCCCGCAGCCTCGGGATGACCTTCGGCCAGACCCTCTCCGCCGTGGTGCTGCCGCAGGCGTTCCGGTCGGTGATCGCGCCGGTCGGCTCGACGCTGATCGCGCTGGCCAAGAACTCCGCCATCGCAGGGGCGTTCAGCGTCACCGAACTCCTCGGCACCTACCGCACCCTCAGCGAGCTGGGCTACAACATCATCTGGACCTTCGTCTGGATCGCGCTCGGCTACCTCATCATCACCCTCACCATCAGCGCCCTGTTCCACCTCATGGAGAAGCGCTGGGGAGTCGCCCGATGACCGCCACGTCCGAACAGGAGCCCTCGGCTCTCTACGACGTCCCCGGGCCCAAGGCCCGCAAGCGCCACCGGATCTTCGGTGTCCTCGCCACCCTGGCGATCGCCGCGATCCTCGGCTGGATCCTGTACCTGCTCTTCGACACCGACCAGTTCACCACCGCCAAGTGGCGCCCCTTCGCCTACACCGGCATCCAGGAACTGCTGCTGCGGGGACTGGGCAACACCCTCAAGGCGTTCGCGTACGCCTCGGTGCTCTCCCTCGTCCTCGGCGGGGTGCTCGCCGTCGGGCGGCTCTCCGACCACCGCCCGGTGCGCTGGGTGGCGACGGTGATCGTGGAGTTCTTCCGGGCCATGCCGGTGCTGGTGATGATCTTCTTCGTCTTCGTCGCGCTCCAGGTGCAGGCGCTGCCCGCCCTGGTCACCGGCCTGACCCTCTACAACGGCTCGGTCCTCGCCGAGGTCTTCCGCTCCGGCGTCAACTCCGTCGACAAGGGCCAGCGGGAGGCCGCCTACGCGCTGGGCATGCGCAAGACCCAGGTCATGGTGCAGGTCCTCGCCCCACAGGCGCTGCGCGCCATGCTGCCCGCCATCATCAGCCAGTTGGTGGTGGCACTGAAGGACACCTCGCTCGGCTACCTCATCACCTACGAGGAGTTCCTCCACGCCGGAAAACTCATCGCCTCCAACCTCGACTACGATTTGCCCTTCATCCCCGTGGTGATGGTGATCTCGCCGATCTACATCGGGATGTGCATGCTGCTCTCGTGGTTCGCCCAGTGGGTGTCCCGCAGACAGCGCCGCGATCCGAAGGCGAAGGCGGCCGCCGTCACCCGGGCCGAACCGGGAGGGCTGCTGCCGGGCGAACGGTAGCGGGCCGACCCGGGGCACAGCGCCCCTGGCCTGCCCGGCAGCAGCCGGAGATCACTTCTCGCGGACCGGGACCGACACGTGACCCGGGTCGTCCGCAGGCGAGGAGAAGGTCAGCTGCGCGCCGGACGGGTTGTGCTCGATGTACAGCGGGTCGACGGTGTCCACGACGACAGCGAGCCGGTGACCGGCCGGTACGTCGTAGGCCGTGGAGTACAGCTCCAGGTCCACGGCGAACGGCCGGCCCGGCTCGCGGTCGTGGAAGGTGTACGGGGCGTGCGTGACCAGCTTGCCGACGCCCAGCGGGCCCACGTCGTACAGGTAGGCCACGAAGGTGCCGCTGCTCTTCGTCGGCGTCACCGTGGTGTGCACCTCGGGGGTGCCGCGCACGGCCGCCCCGCCGCTGTACCGCTCGGACTGCCAGACGGCCGCGTACCGGCGGGGGAGCAGCGGCATCGACGCCATCGGGGGTGTGCGGATCAGCTGGTCGAGGGCGTTGGTGAGGAAGATGATGCCGCCGTTGGCGCCGGAGTCGACGTTGGCGCGGATGGTGTGGGTGCCGGCCAGGTCGATCTTGCGGCTGTCGGCGCCGACCGACTTCCAGTCCGGATAGCTCTCGTAGGCGCCGGTGGAGCGGGACTTGATACGGACCGGCTGCTCGCGGTCGACGCCGTTCTCCTCGCCCTTGAGGTGGTGGTCGAACCAGCGGCGCGCGGAGGTCCAGGTGTCGTTGGGCAGGCCGAGCAGGCCGGTCGCCTCCGAGGTCGCGTGGTCGCCCGGGCGGAACTCCAGCCGCTTGGGGCCGGTCAGCTTCTCGTAGAAGTCGGCGTACTGGTTGGGCGGGAAGAGGCTGTCGCCCCAGGCGTTGCCGAGCATCACGGCGGTGCCGTTGGCGTTCAGCGCGTCGAGGTGGGTGGCGGGGGAGCGCTTCTTCCCCCAGTCGATCATCTGCTGCTCCTTGTCGAGGTTGGAGCCGATGAAGTCGCCCAGGATCTCCTTCAGTTCGGCGCTCGGGCGGCCGGTGATCAGGCCGGAGCCGCCGAGCAGCAGGGCGGCCTGGAGGTGCTGGGTGCGGCCGCTGTAGATGGAGTCGATGAGGTCGGCCCAGCCGCTGAGCGCCGCGACCGTCTTGATCCGCGGGTCGTGGGCGGCGGCGAGCAGGCTGATCCCGGCACCGTAGGAGACCCCGGCCATGCCCACCCGCTCCGGGTCGGCGGGGGTGTTGGCGAGGGCCCAGTCGATGACGGCGGAGGCGTCGGCGATGTCCGGCGGGCCGGCCACCTCGATCTCGCCGCCGGACTGCCAGAAGCCGCGGGAGTTGTAACTGACCACCACGTAGCCGGAGTCGGCGAGCTGGGTGGCCTGGGCCAGGTACTCGATCTGGGGGACCGCCCAGCTGGTGGGCAGCACGATCACCGGATGGCGGTCGCCGGCGGCGGAGCCGGCGGGCGTCACCACGTTGGCCTTGAGGACGGTGCCGTCGGTGCTGGTGATGTCGACGAAGCGGATGCCCGAGGCCGAGGTGCCGGCCTGGGCCTTCGCCGGGCCGTCGGGGGCCGCGTGGGCGGGGGCGGAGAGCGTACCGACGGCGAGCGCGGCGGTCAGCGCGCAGGCCGCGGTGGTGGTGAGGGCGGGACGGGGGCGTCTCATGGGTCACTCCTCGCTGCGGGCAGGGCAAGTGACCCGACGGTAAGCGGAATGACTTACCGGCGGTAACCGGCGGGTAGGTTACGCGCCAGTAACGATTGTGGGCCGCCCGGCCCCCGCGCCTACTTGGCCCGGTGAGAACTGCGTGCGGCGGGGACCGGGGCCGGCTCCTGCGCCGCCTTCGTCACGTCCGCCACCAGCTCCACCACGTCCGAGCCGTACGCCGCCGAGTTGACCACCTTCAGCAGCAGGACGAAGGTGCCCGTGCCGTACTTGCGCGCCAGCTTCTCGTGGTGCCGGGCCAGGTAGCGCGTCGCCGCCTGCGGCGTGATCGGGCGCTGCCCGCAGAACAGGAAGACCGGGCGCCCGCCCTGGCCGCCCGTCAGCCGCGCCAGCAGCACGTGCTCGCCCACGCCCTGCTCCATCCGGTACCGCTCCCCGCCGATGAGGAACGCGCCCCGGTCGGGCCCGGGCTCGGGCTCGGTGTTGATCCGCACGCCCGGCAGGAGGGAGGTGAGGTGGGCGGCCATCCGGCGATTCGGACACGGTCCAAGAGTCCCACCTTGAACTCACTTTCGTGACAGGCGCTTGACCTGCGTATATGCAAGGCCCCGTCTCGTTGGGGGCCTTCGCGATGCAGCAGAACGGCTGTTCCGTAGTTATAGAGAAATGCCCACGGCACCCATCTTCAGAGCGAGCTGGAGGTCTCCGGTAGGGGTCTGGCCTGCCGATGGCACGAGCCTCCCGGTGGAAGGTGCAGGGGCTGCTGACGGCATGGTGACGATTCTGACCACCAGCGCCGTTTCGGCGTGAAGTGGCTGTGCGCCATCCTGGACCGCCCGCTCCGGATTCTAGAACTGGCGCTTGATCGTCGAGGCCTGCGCGGCCCGGTAGGGGGCCGACGCCCGCCTGGCCGCCGCGGTTACGGGCCGTGCACGGCTAGGGTGATGTCCCGATACCAGCCGATGTAGCTCATGGACAGGCCCAGGTCGGAACCGCTCTGACCTGGGCCTGTCGCGCGCTTGTGGGATGCGCCGGGGGTCACCGCGGGTCGGGGCGGGTGCGGAGGTTCCGGGAGCCGGCAGTCGGCTCTGGTCCTCCGCCCTCGCGCGAGCGGCCCCGGGTGAGGAGCAGCGTGAGGGCCAGCAGGGAGAGGACCCCTGCCACCGCCGCGGGCAGTACGGCCGGTGTGCCGCCGGGTTCCAGGGCGGAGGTGAGGGCCTGGGGGCCGGTCGCCGGGGCGAGCAGATGTGCCGCGGTCAGGGAACCCATGAGGAGGATGTCCGCGATCAGCGCCGGCAGCACCCGGCGCAGGAGCGTGCCGGCCGCGAGCAGGAGGCACAGGACCGCGATGCCCACCGCCAGTCCGTACGCGCTCGTCGGCAGACCGGTCGGCTGGAACGGGAAGTGTGTCACTCCGCAGAGGAGCAGCGCGGCGACGGTCGTCCAGCGCAGCCACAGGGGGAGCGCTGCGGCGGGCGTGGCCTGCCGGTCCTGGGTGGTGGCCTCAGGGGCCTGCCGGGGGCGGGAGGACGGGCGGCGGCCGTCCGCGAGGGAGGGTGTGGGTCGTGTCGTGGGGGTGTGCATGGTCGGCGCCTCAGTCGTCGAGGCCACGGTCGCCGTGCCCAAGGTGTGAGCGGTGCTCGCGGAGTCGCCGTCGGGCAGGGGGGAGCCGGTCGGCTCCTCCTCCGAGGGCTCGGCCGGGAGGGCGGCGGAAGGGGGTGTCGTCCCGGTTTCGGCGCCTGCCACGCGTTCGGTCTCCAACCGGTCGATGAGCTGGGCCAGTTCCTCGACCGTCAGCCCCGTGGCGGCGGCGTGGACCGCTTCCTCTCCCGCGTGGGAGTCGTGGGGTGGCCGGTGCAGGAGGGCCACGAGGTCGCTGACGTCGTCGATCGGCCGTTCCGCGGCGGCCAGGTGGATTGCCTCGTCGGCACGGTCGACCGGCTGCGGAGGCTGGGAGAGCAGGGCGACCAGGTCGGAGACGTCGTCCACGGGGCGTTCCACGGCGGCGGTGCGCAGGATCTCCTCCGCGGCCTCCGCCCCGCTCGGCGACTGCTCCAGCAGCCGGATCAGGTCGACGATCTCCGGCACCGACCGCGTCGTGACCGCTGTCCTGACCAGGCCGTCGACGGGGCGGGCGGCGGGCTCGCGCTCGGGCGCCTCGGAGGAGACGGTGTCCTGTTCAGGCCGGGCGCTGGTCTGCCGGGTGCCGGGGGCGTCTTCCGGCGTGGTGTGCGCCGTCGACGGTTCCGCCGTGCCGGACGCGAGCTCTTGGGCCGATATGCCGGACGTGAGGTCTTCCGATTCCGTCGTCATGTTTGCCTTCCGTTCGAGCGCCGTCTCAGTACGGCGCTGCTGCACAGGCATCCGCGGACTACCAGCCTTCCTAGCCTTTGCGTCGGCTGACGACGACCGGGACAGGGCCGATCGAGTGACCTCGGCCCCCCTGCGTCGACGGGCGCAGGCGGGGCCGGGGCCGGCGGTGCTGCGGGACGAAGAAGGCCCGTCGCCCGCGACGTTGGGGTCAGGCCGGCGAGGAGCCTGTCCTGAGCTCCGGCCCCCCCCCCCGCGCCCACCGCCGTCATCCGTACCGGCTCCGTCCCCGTGGCGCTGTGTCGGTCCGACCGGTGCTCAAGGGCGGTGTGGCAGGCGTGGTCGAGGTGGCGGAGGCCGGAGAGGTTCTACGGGCCGGTGGGAGACGGGACGTGTGTGACCCGCGCGGTAGCGGGGCCCGTTCTATGTGTCGCGGTCGGGTGCTGGTGCAGCACCGGGCCGCCGGGTGACGAAACCGTACAAGGCTGATGCGCCGCCGCAGGGTGGCACCACGTCCGCTCGAAGGTGGCGGATCGTGCGGGGCGTATGGAGGATGCCGACTAGGGCGTCCGTTTCGTCCTTTACCTACTACATGGTCCGTCGCAGGTGAGGCCGACCTCGTCGGGACCCGGTCGGAACACGTGATGGGTGTGAAGTCGCGGAGGCTGTTCTGCCGGGCGTGGGCCTCGGCGCCTCGCGCCCGCGGGCGGCGCAGTGGGCGTGTCGATTAGCTGGGCTTGTCTGCGCGGGCTGGCCTTCGCGGGCCGGCTGTGGGGAGACACGGTCGGTACCAGCCGGGGCGCCCGGACGAGCGGTGGGCGAGGTGCCGTGCTCACCCGTCCTTCCCGGCCGCTATGCGGCGTTCCGAGCTTCGGTTGGCATTTCTGGACGACCGCGGTTGCTCAGGATGTGGTGGTGGACCGTCCGCCCAGGCGCCCGGCCAGAAGGCGCTCGGGCACGCCCTGCAACTCCAGGTCCTTTCCGGTTCGCTGAACCAGTGGCCCTCAGCCTTGTTCAGCAGGTACTTCACCTCGGCGCCACGCGCGCAGCGCGTCGGCGATGCGGTCGGAGTGGTGAAGGGCGACGCGGACTTCGTAGGCGCTGTGGATCAGGAGAACCGTCGGTAGGCCGCTTGCCTCGGTTCCGACCGGCAAGGTGAGGTGTCAGGGCAGGGGAACCCGTCGCGGGCGGTGACGACCGGATCCAGCTGGCGAGCCCGCCTCGTGATGTGGTCCGTCGGTGAGTAGACAGGGCGGGAAATGCCTACAGCAGCCGGGGGCGGCCCGTGGGGACGCCCCGGCTGCTGTAGGGGGCACACGGTTGCCCACAGCAGCCGGGGGCGGCCCGCCGGACATCTTGGCTGATGCGCCTGCCTATTTGCCGGATTTGAGCGCGGACCAGGTGGTTGGGCCGACTACGCCGTCCGCGGCGAGACCGCGCGACTTCTGGTAAGCGATGACTGCGGCCTTGCTGGCGGCGCCCAGCTTGCCGTCGACATCGAGTGACCTGCCCAGGGTGGCGTTGAGGCCGCGCTGCAGGTACTTGACCTCCGTGCCGGTCGACCCCTCGCGTAGCTTGGTGCCCTTGGCCGGTGCGGTGAGCAGGGCGCCCCACGTCTTCGGGCCCACCACCCCGTCGGCCCCCGTGCCGATCTTCTTCTGGAACGCCTTCACCGCCGCCAGCGTCTTCGCGCCGAAGACTCCGTCCTTCTCCACACTGTGCCCGGCCGTGACAAGGTGTGCCTGCAAGCTCTTCACCGCATCGCCGCGGTCGCCCTCACGCAGCTTCGGGTACGCGTCCACCACACCGCCCCCGCCCGGCAGGCCGGGGAACGAGTAGGAGATGGTCCTGCCCTGCGACACGGCCGATCCGCAGCGGAAGTTGTTCAGGAGCGAAGAGTCGCGTATCACCACGTCGTTGCGCTCGACCTGGAAGTGCAGGTGTGGCCCGGTGGAGTGGCCGGTACTGCCGATGGTGCCGATCACCTGGCCCTTCTTGACCTTCTGGCCGGTGGAGACAGCGCGCGAGTTCAGGTGCAGGTACCTGGTCTCCCAGCCGCCCGCGTGGTCGATGACCACCCGGTTGCCCGGGCTGGCCGCCTTGTCCGACTGCCGGACGGTCCCGTCTGCGGATGCCTTCACCGAGGCACCGGTCGGGCCCGCGATGTCGAAACCGTCGTGCGAGTTCCCGGAGCGGCAGTAGCCGCTGGGCGACCCGGTGATGGTGCCGCTGGCGGGAACGATCATGGCGCCCTGCTCGGCCGCCGCCGTCCCCCCAGCCAGCGCCACGCCGCCCGTGGCCAGCACGGCCACGGTGACGAACCCGGACGCGGCTCTGACCGCGGCGAATCTCGTCGGCCGGAAGCTCTTTCGCATGACCTGACGTATCATCATGTGCCTTTCTCTGCTCGGTAGTTCGCATGGTCGACGCGCGTAGAGGAGCGTAGCTCCCGACGGCCCGGCTGTGGAGTCCTCTGCACTGCCGGGTTAGCTGGGCCGGCACTGGTCTCGGCCGCCGGGTACTGCCGCCCACGGGTGGCCAGGTACCGCTGCGTCCTGAACCCGGCGGCGTCGGGGCGGGCACCCGTCCGCGGTTGCCCTGCCACCGGCAGTCAGGAAAGGGGCCAGACGCTCTCCTGGCCGAGTGACCGGGAGATGTGCCTTCGCCTCTCACATTCCGAACTTTCCTCAGGAGCGGGAGGAGACCGGGTCTCCTGTCGTCTCCCGCCGGCGTCGACAAGGGGTCCGTTGGTGCGCGGACGTCTGCCTTCCTGCCGTACGCAGCAACTAACGAGCTCGTGCACGGTAAGCGGTGAGACGTCGCGAGCCTCGGTGCGACCTGGGTTCACGTCTGCCGTGTCGGCTTCAGGTCCACGGTCTGCTGGTGGGACAGCAGGCCAGCGACGGCTTGGATGGTGTCGCTCATATGCTCGCGGCGGCCGAGATGACGGGCCAGGGCCCGCCAGTTCTTCAGATGGGCGATGCCGTGCTCGACCCGGATACGGCGTGAAGAGTGTGCCTTGCGCTGGCGTTCGTGCATCTCCTCGTACCAGTCCGGGGCGTTCTTCTTGAACTTGCGGTGCGGTGGCGTCACCACCCGGCCACCGGTCTGTGCGCCCAGGCCCTGGTAGCCGGCATCGGCGAGGATCTCCACCGGGGGCCCGTCGGCCAGGAGCCTGACCAGCCCTAACTGGCGGGCTTGGGTGATGTCCGCGCAGCTTGCAGGCCGTGCTGGGCTGCACCAGAGCACGTGGCCTTCGCCGTCTGTGACGACCATGGACTTGACGGCGTTCTGCTTGTTCTTGCCGGAGATGAACTTGTCGCGGTCCTTGCGTCCGGCGGCCGGGCGGCGAACCCGGATCTCGGTACCGTCGACGATGCCGGTCGTCCCGCTCGAGCCGAGATGGTCGATGACCTCGGCCAAAGACCGCAGCCGCACGTCAGGGCTGACGGTGCACCCTCGCTCGGCGAGCAGGGGCCGCACCTCACCGACGGCCCGGGTGATGGTGGAGCGGTCCACTCCGAACCAGCAGGCCAGCACGTCATGGGTGGCCCCATGACGAAGATGGACGAGCGTGGCCAGGAGCCGGTCGACGAACACCAGCCGGTGCTTCGCGCCGGCGCCCACCGCCCGCTTACGCGATCGAGCGGCAAGCCTCGCCTGGTGACGCTCCTGCCACAACGGGCCGATCTCCTCGACGAGTTCAGCAATCACGCCGGCAGTCAGGCCCGTGATCCGCCGATTGCTGATGATCACCGCACGCGTTGCGTTCCCCACCACCTGACCATGATCAACCATCCAGGCTCGACGTCTCACCGCCTACCGTGCACGAGCTCGTAAGGGTTGTCCCGCAAATGATCTTCGGGTCGCCTCGGGTATGGGGGAGGCCGTTGTGCGGACCGCCGGTTTATCCGGTGAGGGCGAGGTTGTGCATGCGGGCGATGCCGAGCATGGCGTGATGGACGCCGTCGCCCTTCAGGCGGCAGTCGCGGAGGATCTTCCAGGTCTTCATGCGGGCGAAGACGTGCTCGACGCGGGCTCGGACCTGCTTGTGGGACTTGTTGTGTTCCTCTTTCCAGTCCGGGAGTCCGGCCTGTCCGCGCTCTCGGCGGTGCGGGATGACGAGTCCGGTGCCCGGGTAGCCGCCGTCGGCGATCGTGAGGGTCTTGCCGACGGCGGCCTTGGCGCCGGATTCCTCCCATGCCTTGCAGTCGTTGCGGTTGCCGGCGAGCGGCCGTCCGACCACCACGACCAGGCGGGTGTCGGCATCGATGACGACCTGGTGGTTGGTGGAGTACCGGTAGTTCTTCGACCGCTCGGCGATGGTGTGATCCCGGGTGGGGACCAGTGTGCCGTCCACGATGAGCACGGTGTCCTTGGCGGATCGCTTGCGGGGCTGGAGCGCGAGCATCGGTCCGAGGTGGTCGATGATCCGGTCCGCCGCCGACTTCGACACCCCGAACTGCGGGGCGAGCTGCCGCATGGTCAGGTTTGTGCGCCAGTACGCCGCGACCAGCAGTGCCCGGTCCTCCAGGGGCAGGCTCCACGGCCGGCCCTTGCGGACCGCGTCCGCACCCTCGCGACGCAGCACCGTCACCAGCTTCCCGAACTGCCTCGGGCTCAGCCCGCTGAACGGGGCAATCCAGGACGGCTCCGACGCAGTGATCACACCAGTCACGCCAAGATCATCTCATCTGTGACCAGCAGTTACGGGACAGCCCTTAGCCCTCTGAGTCAGGAATTCTGTTCAGATAGCTGGCGAGACGTTCGAGGGCATCGTCTGCGGGCACCATCCTTGTTGTCCTCGCTGCCCTGTGGGCCCTCATGCCACGGCCTGACCCCGGCGCCGGCTCGGTAGACGTCACGCGCTTGGGCGCCGAAGCGGACGCTAACCGCCGTTCGAGCCTCGCCCAGCTCGTTGACCCCGCCTCCCACCCCTAACTGGTCGTTTCAGGAGGAGTTGAGCTGTAGGTCTTGCACGTGCCCATCTTGGTCGGCAGGGTGCCGAGGGCTGATCTTGCCCCGGACGGCCCATGGGAGCGGGTGGCACCGCTGCCGCCATCCGCTTCCGAACGGCATCTCCGGTGCTTTCAGTCGGCTTCGCATTCCGGCCCGCCGCTCTCCCCGGCAGCTTGTCTGCCCTGCCGTCCGGCGACGCTTGGCACGACGTTCCGGCCGAGACGGGGGCTACTCCGGTCACGATCTGGCGCCTACTGCGGTCCTGGACCGAGGCCGGCGCCAGGCCACGCCAGCACGCCGCACCGTGCGGCGCGGACTTGCTGGACCTGGAGGACAGCGCTGAGGACGGCCCCACGCCTATGCCCTTAAGCCAAGCCCTCGCAACGATCGACCCGCCATCGGTGCCGCCGCCTACACCTCGGCTACGAACGCAAGGCGGACCACTTCGTGCCTTCACGAGCGTCGCCTGCAACCTCAACCGCTGCTCTTCGCTGTCGGCCTCTAAAGACCAGGGCCTTGAACTACCTAATGCGCTCGTCGAGGATTTCACTCCTGGTGATGCCTTCAGTGCCCGTGATAATCGGCGCAATAGCGGTCGGGAAAGGCTTCTCCGTTGCGCGCTGACGGCTTACTGATCGTTTCAGAATGCCGTCCTGCGGAGACGCTGACGGCCCCATGGAACAATCCCTTCAGCTACGGGCTCAGGGGGGATGGCGCCGTATGGAACGTGTTGGGGCTGCACGGGACCTCGTGCTCGCTTACGTCCACGATCTGAACGCGATTGACGAGGCCGTGAGGGTGGCGATCCCCTCGCTTGAGCGACTGGCAGATGTTCTCGGCCTGGCTCGTTCGCGCCAGATCAACCGGAGTGGGCACGTCGGCACCTACTCCTACACGGTTCATGGGGCAGGGTGCCGCTTCGTGTGCGACAACGGCACTGAGGTCGATGTGGACTTCGCAGCCGACGGGGGCGAAGTCTTCGACCTCTGGCGGCTGCGTTGGTATGGGCTGAGCCTGCCGGAGCCTCTTGACGTCACGGATCAGGACCTGCGGTCCGCAGTGCGGTCCCTGCAACCGCTTCTGACCGAGGTGCGGCCGGGGTGGTTCAGCGTGGCCAACTGATCGCTTCAGGATGAGGCTCGCAGGCGGCGCAGGCATATGAGGCTGCAGGCCAGTTCGAGCAGGCCCTGGCGCAGATCGGCGCGTCGTTCGTATCGGATGCGGAGCCGTTTGAACTGGTGCAGCCAGGCGAAGGCGCGCTCGACCACCCAGCGCACCTTGCCCAGTCCGGAACCGTGGGCGACGCCGCGTCGCGCGATCAACGGCTTGATGCCCTGCTTCCACAATAGGCGGCGGTACTTGTCGAAGTCGTAGCCCCGGTCCGCGTACAGACGCCGGGGCTTGCGGCGGGGGCGTCCCCGCCGGCCCCGAATCGGCGGAACCGCGTCGAGTAGCGGCAGGAGCCGGGTAACGTCGTGCCGGTTGCCGCCGGTGAGGGTGACGGCGAGCGGGGTTCCGTGACGGTCGACGATCAGGTGGTGCTTGGAGCCGGGGCGGGCGCGGTCGACGGGTGAGGGACCGACGTGGTCCCCCCTTTTGAGGGCGCGGACGTGCGACCCGTCCATGGAGCAGTAGTCCAGGTCCAGCAGGTCGGCGCGGCGCAGCTCGGTCAGCAGAGCGGCGTGCAGGCGCGGCCACACGCCGGCCTCGGTCCAGTCCCTCAGCCGACGCCAGGCCATCACCCCGGAGCAGCCCACCGTCTCCGCGGGAACATCACGCCACGCCACACCCGTCCGCAGCACGTACAGGACGCCGGCGAGTGCCGCTCGGTCGGGAACGCGCAGCCGCCCGGGATAGCGGTGGCGCCGCTCAGGAGCCGACGGCAACAACGGGGCCACCCGCTCCCACAGGTCGTCAGGAACAAGATCAGCGCGCACGCCGGACACCCTGGCGACCAAGATCGTCGAGCGCAAGGCCCGCGACTCAACTCATTCTGAAACGATCAGTTAGCCCCGTCGCGCGATCACCGGTGCACACGAAAGCGCCGAGAGCAAAGACGACAGGCGCTTCCTGATTGCGTGTCCGCTCCATCAGCGGGAGACTCACGGAGGGGGTTTGCATCCTTCGGATGCACTGTCCGGGTACATCCATCGGGCCGTAGAGCTCGCCGGCCAGAAAATCTAGCGTTGCCATCATGACAACGAATCACACTGAGTCCGCCGACGTCCCTGCCGACGGCCTCCTGCGGAACAGGTGGCGGGCGAGAATGCGGGCCCGTCCCCTGACCTTCTTCTTCGTGCTCGCGAACGGCCTGAGCTGGGCGGCCTGGCTGCCTTACATTCTGTCGCAGAACGGCCTCGGAGTCTGGGACTACCAGTTTCCACAGATCCTGGGGACCAGCCAGGTCCTGGGGGTTCTCCCCGGCGCCTATCTGGGGCCGATCGGCGCCGCCTTCGCGATGACCGCGCTGGTCGACGGCCGGCCCGGCCTGCGGGCCTGGGTGCGCCGACTGTGGCGGTGGCGGGTCGCCGGCCGCTGGTACGCGATTACGTTGCTGGGTGTCCCTGTCGGGATGCTCGTGACGGGCTTGGCGTTCTCCGGTGGTCAAGTCGCCGCGCCTTCGGCCGCTGCGCTCAGTGCCATCGTGCCGGTGCTGCTGTTCCAGATCGTCACGACCGGTCTAGCGGAGGAGCCCGGGTGGCGGGACTTCGCCCTCCCGCGCCTGCAGAGCCGGTTCTCGCCGCTGCGCGCGGCGTTCATCCTGGGCCCGCTGTGGGGCGCATGGCACCTGCCGCTCTTTCTCACCGAATGGGGCGGCTATCCCGAAGCGTCCTGGACACGGCCGCTGGTGTTCCTCGGATTCTGCGTCGCGTTCAACGTCGTCATGTCGTGGGTGTTCAACCGCACCGGGCAAAGTGTTCCACTCTCCATACTCATGCATGTGGGGGCCAACACCTTCGCGTCCGTGATGTGGGCCGAGATGTTCCCCGGACTGGACGGGGAACTCGCCCTCATTGCGATGGGCTCCGGTGCCGCCGTCGCCGCGACAGCGATTGTGATCGCCACACGTGGCCGTCTCGGCTACGCTCCCTCGCCAGCCGATCTCTCCTCGGGCCATGGCGGCATGGTGCCGTCCGCCTGCCGCGCGAAGTACAGCCAAAACCGACCTATGATCGAGTCGTGAAGACGGCGCAGCGACCAGGCTTGACTGACTCCGCCGCAGGAGTGGCAGCGGCGGTGACCGCACTGAGTGCGCTGGCCCTCCTGTGGATCGTCACTCTGCTCGCGCGTGACGACCCGTCGCTTGGTGGACTTCCCCACGGTACGGTCGCGTGGTGGGTGACGGCTGTGACGCTCGTCCTGCAATCGGCGACTCTTGTGTGCACCCGCCACCGGGCCACTGCGGCGTTGGCCAGCACGGCTGCGCTCTCCCTCGTGCTGGCCGTCGTGTTTCCCAGCGGACTGTTCACCGTCACCGCGCTGCCAGTGCTGGTGGCGGCGTTCCTGGCCGGGCTGACCGAGGCCTGGCGCGACGTGCGCCGGTGGGCTCCGGCCTCGGGAGCGCTGGTGGCGGTGGCATACTTCGTGAACAGCACCACTGACGGAAACTCGGACGGTACGGCTCTGTCCATGCAGGCGGTGCTCCAAGCGGCCTTGGTGGTCGGTCTGCCGCTGCTGCCGGCCTCCCTGATCGCTGCGCAGCGGGATACAAGGGCGGCGCAGCAGGAGACACTGGCGGCGGTCACCCGCGAGCGTGACGCCAAGATCAGTGAGGCGATCGCTCTGGAACGGGCTGCGATGGCTCGCGAACTCCACGACATCGCAGCTCACCACCTCTCCGGCATCTCGATCATGGCCTCTGTCGTCGCCCGACAGACCACCTCGGCACCAAGTGAAGCGCGCTCCGGTGCGCTGGAGATCCGCAGGCAGAGCAACGCAATTCTGGAGGACCTCCGCCGCCTGGTCGGTTTGCTCCGCGACGTTGGTCCCGACGACGAGGAAGTCAAGACCCTCATCACCATCCCCGGCCTGATCGAGGCAGCGCGCCTTGCCGGAGCCCGCGTCGAGTCCGATTTACGGATAGCTGAACGGCGGGAGCTAGGAGCGGGGATCGGTCCGCTGGGGCAACTCGCCGGGTATCGCATGGTGCAGGAGTCGTTGACCAACGCCTCACGACACGCACCCGGCGCGCGCTGCCTTGTCACCGTGGACGACCGCAGCCCACTCCGGTTGCAGCTCACCGTCCGCAACGCACCACCCAGCGGCGCCCAAGTCCGCCCGACTCCCTCGGGCACCGGATTCGGCCTCATGGGCATGAAAGAGCGCGCGCTACTCATTGGTGGAGACTTCGACGCCGGCCCCACCGACGACGGCGGCTGGGAAACCCGGATGAGCATTCCCCGTGAAAGCGAACACAACTTCCCGGAGCCTCCCACGTGATCCGAGTTCTTCTCGCCGACGACCAGCCTCTCGTCCGCGCCGGCCTGAGCGCACTGCTAAACGCGGAGGAAGACATCGCTGTGGTCGGTGTAGCCGCGAACGGCGCCGAAGCCCTCGACATGGCGGTCGAACTGGCGCCGGACGTCGCGTGCCTGGACATCAGGATGCCGAAGATGGACGGCATCGACGTCGCGGCCCGCCTCTGTGGCCCTGACGCGTCTCCAGCTGTCCCGGTGCTGATCCTCACGACATTTGACATCGACGATTACGTTTTCCGGGCGCTCGAAGCGGGAGTCGCCGGGTTTCTCCTCAAAGACTCCGACCCTGAAGAAATCCTGCGCGCGATCCGCCATATCGTCGCTGGCCACGGCACGCTCGACCGCACTCTCACCCGCCGCATCGTCGCCGAGTACGTGCAGCGGCGCCGCCTGCGGCCCGTGACCGCCGCACGGGCCATCGACATCCTCACTGCCCGCGAACGCGACATCCTGCTGCTCCTCGCGCAAGGGATGTCGAATGAGCAGATCGCCCAAGCTCTCGTCGTCGAGGTCGCCACAGTCAAGTCACATCTTGCACGGCTCCTCCCTAAACTCGGCGTGCAATCCCGCCTGCAAGCCGCCGTATGGGCCTATCAGAACCGTGTCGTCACCGTCGACGACACTCGGCGCTGAGCGCATCTCCCGACTCCGAAGCCATCGGCTGACAGCCGTGGTATCGGCCGTCGATATTTCTACCGATACGCCCGGGCGTGAACAGTTCTACGAGCGCTCAGGAATCACCCGGTGTTGCAGCAGCCGTGCAATATTGAGCAGAATTTCCTCCCTAGTGGAGCCCAGTTGGTGAGGGAAAGCGCCTTTGCTAGTGATCCGTTCCCACAGCATGGGGGTGGATCTAGCAGTCGCATCCAAGTCTGTCCAGTCCTCGAGACCGGAAAGTGAGGTCGTCTGTCGATAACCGAATCGTGGCAGGCCAGCCTCGGACGGTTCAACGAGGCGCTCGATCGCAGGCCAGTCGGAACCGTGTGGTAGCAAGAGCTCCAGCACGCCCAGTACGGCGGCAGTCGCGGCGAGAGATGAGCTGGAAGAGGCATATCCCGAAGCAAGCGTCCGCCTCATCTCGCCAGCGGAGTAGATGCTTTCCACTAGATCCGCTTCCCCGTCACTTCGAACACGGATCTCGCTATGTAAAGCCACCTCCGGCAGTATGACGCTCCAGCGAACAGGCGCTTCGTGAGCGCAACGCACCGCGTCGGGGATGGTGGGACAGGAAAGAGTCAGGGTGGATCGTGCATACGCAATGGTCACGTAAGTATCAACTGACTACCCGTTGGATGGTCACGGCACGACTCGGACGTGGGCTTTCGGGCGCCCGCGCTATGCAATCGACCCTCCCAGGAGCTCACATGCACCTAGCACGATGAGGTGGAGTGTCCCTGACTGCCGTGTCCAATAGGGGGTTGAGCGCTCGGCCTAGTTGTACTGCCCCGTGAGGTTGGGGACGCGGCTGGCGGGAGGTTGACCCTTGAGCGCGGTGTGCCCGTGGTGGTGGTTGTAGGTGCGCAGCCAGAGAGGGTAGGTATCGCGCCGTTCGGCCTCGGACTGGTAGGACTTGGAGTAGGCCCATTCGTCGAACCGTTCGACCTTGCCATTGGTCTGGGGGCGATAGGGACGGGTCCGCTTGTGTGCCGTTCCCTGCTCGGCGGGGCAGTTGCGCCAGAGGTGGGGGCGGTAGCAGGAGCCGTTGTCGGTCAGGACCTGGCGGATGGTTATGCCAGCAGCGGCGAGGTGTGGGCCCGCTGCCAGAATCCAACGGCAGTTTCCTTCTTCTCGTCGACCAGGATCTCGCTGTAGGCGAGCCGGGAGTGGTCGTCGATGACGTTGTGCAGGAAGCTCATCCCCGCCTTCGCGCGGTTCTTGCGGCCGGCCCGCCTGCCAAGGACCTTGTGACCGCCGCCGTTAGGAATGTTGCCGAGTTTCTTGATGTCGACGTGCACGAGGTCACCCGGAGCGGCGTGTTCTTAGCGGCGGATTACCCGGCCAGTGGCCCGGTCCACGTGAGACAGGCGAGCGAGGCCGTAGCGCGTCAGGACGCGGTGAACCGTGGCCGGGTACAACACGAGGAGGTAGGCAATGCGGGCAGGTCCCCAGCGGCGCGCAGGATGCGGACCTTAATGGCCCGGCGCTCGGTACGGGTGGGAGTCCGGCATGGGCTGCGGTGGGGCTTTGAGGAGCGGTCGGCCGTACCGGCCTCACCGAGTTCGCGGTAACGGGCGGCCCACCGGTAGGCCGTGGTGGGCGAGACCTGGAAGCGTTCAGCAGCCCGCCGCAGCGGCCAGCCGTCCTCGACAACGCAGCGGGCCAGGAGCAGGCGGCCGGTCTCGGTCAGGGGTGCATTGCCGTGGACCGTGCGGGGCTTTCTGGCTCGGAGGATGACGAGGGCCGGGTGTACGAGTGACGTCTCGTGCACCCGGCCGTCATGTGGGCCGTGCTGCGGCTGGTGGAGGTCGGAGCCTCCATACCTGCCGTCAGTGGGCGCGCGCTGGACGTGCCCGTTCTCCGTGGTGTCCGGGTCAGGTGGTGGGCTGTGCCGCCTTCCAGGCGCGGTAGTACTGGTGGGGGGCGTCGGTGAAGGAGGCGTGGCGGGGGCGCCAGCCGAGGAGGCGGTGGGCCTTGGCGCTGGTGACGAGTTCGTCCTGGTCGGCGGCCATCTGCATCATGCCGCCCGCCTCGGCGCTCTCCAGGGCGATCTCGCCGGTGTGGCCGGCGGCTCGTACGGCGGCGTGCTGCATGTCCAGGGCGGTCAGGCGCTGGTCGTCGGCGATCACGAACACCTCACCGTCGACGGCGGCGGGGTTGTCGAGGATGCGGACGTAGGCGTCGGCGAGGTCGTCGACGTGGACCCAGCTCCAGCGCTTGGCGGTGTCGCCGTAGAAGACGGGGTTGCCGGCTTCGGCTGCGGCGAACCACTGGCCGGTCATGGAGGTCGTGGCGGGGCCGCCGTACATGAAGCCGGGGCGGACCACGGTGTGCGCGAGGCCGGTGGCGGCGAGTTCCTTCTCCAGGGCGAAGCGGAAGCCGATGGGGCTTTCGGGGTTTCCGGAGGTGTTCTCGTCCATCAGCGGCAGTCCGGTGCGGCCGTAGGAGGAGATGCCGGTGGTGAACACCAGGTGGCGGTGGCGCCCGTCGCGCTCCTGGGCGGCGGCGAGTTCGGTGAACAGTCGCTGGTCGGCGCCGACCGGGTCGTTCATGTCCATGAGCAGGTGCACGACGGCGTCCGTGTCGTCCAGGTGGCCGCGCCAGGTGTCGGGCTTGGAGAAGTCGCCCTGCACGGGGGTGACTTCATTGACCGCGAGGTCCCGGGAGGCCGGGGAGGCGGTGTCGCGGGCCAGGCCCAGAACGGTGTGTCCTGCGCGAGCCAGTGCGGCGGAGACGCGGCGGCCGGCGTAGCCGGTGGCGCCGATGACGAGGATCTGCATGGTGGTGCTCCGTTCTCAGTGTGGTGGGGGTGCCCCGCGCGTCAGGCGGGGGTGCTGGTGAAGAATGGGACGAGTCGCTGCGCGGCCCCTGCGGGGTTGTCGGCGGCGAAGGTGTGGGCGGCGGCCGGCACGATGTCCGCGCGCACGTCGCGCGCTGTCTGCCGGGCGCCGTGCAGGAGGACCTGTTGCGGCAGGCCGAACTCTCCGTTCAGGACCAGCACCGGCATGGCAAGAGGGGCGGAGTTCCGGGCGGCGCGTCCGTCGTCGACGAGAGTGGCGTAGTGCTCGAACCCGCCGCGCATCGCGTCGGGCGCGGTGTAGGCGCGCAGGAGGTCGGTGCGGTCGGCATCAGTGATTCCGCCGCGGCTCATCATCGACCAGAAGCCCGACAAGTACGCCTCTTCCTTGCCCTCAGTGAGCATGGCGGCGAGCTCGCTCTGGGCGTGAAAGCCGAAGTGCCACGAGCCGCCGGTGGCCGGGTTCATGTGGTCCTCCAAGCCGAAGCCGGGCAGGAATGCCTCGCTGAGTACCAGCCGGGCCACCTCGTCCGGGTATGCCTGCGCCCAGGCGTGGGCGGTCATCGTGCCCACGTCCGTGCCGACCACGAACGCCTGGTCGTGGCCGAGGCGGCCCATGAGCTGGTGCAGATCCTCGGCCTCGTCCCGCTTGGTCCAGTGCCCTGCCGGTATGGAGGAGTCTCCGGAGCCGCGCAGGTCCGGCGCGATCACCGTGAAGCCGTGCTCGGCCAGCAGCGGCATCACCGTGCGCCACTCGATCCAGCTGAACGGCCAGCCGTGGATAAGAACAACCGCGGGGCCGCTGCCGCCGATCACGTAGTGCAGCCGGACGCCGTTGACGTCGGCGTCGGCGTGCGTGAACCCGTCGGGTGCGGGAGCGGGGGACGGCATGTAACCACCTCACTAGTTTGCTTGCTTAAGCAATAATCTCCCTACTTGCTTGCTTCGTCAAATACACTCGGAGCATGCCAGCCGACGCCGCCCCCCTGTCCCCCGACGAACTCCGTCTCTGGCAGAGCCTGGGCCGACTGGTCCACTCCCTGCCGCGCGTGCTCGAGGACGACATGTCCCGCACCGGCGTCACCATGACCGAGTTCGCCGCCCTGCTGCTCCTCAGCGAGGCTCCCGACCACCGCATGCGCATGTCCGCGCTCGCCGACGCCGCGGGGCTCACTCCCTCACGCATCACCCGCGTCGTCGACGGACTGGCCAAGCACGGACTCGTTCGCAAGGAACGCCACGGTCACGACGGGCGCGGCAACGACGCCATACTCACCGAAGCAGGACTGCGCACTATGCGAGAGGCACAGCCTGCGCACCTGGCCAGTGCCCGCACCCGCGTTCTCGACCAGATTCCCCCCGACCAGATCTCCGCACTCGCCCAGACCCTCGCGGCCATCGCCGAGCGCCTGTCCACGCATCGTCGCGACGCTTGAGACAACACATGGCCTTCGGGTCAACGGTTTAGCTCCCAACAGTGCGGCGAGCACGGGAAGGCATGTGGAAGAGGGGTCACTCCACTCTCTGCAGCGGCGTGCTGCCGCTCTGACAGATCTCACTGTTCCACCAGGCTCAGGAGCCTGCGGCGCAGCCACGAGGAATCATGGCCAGCAGCGTGGCCCCGCCCGACTCGTCGACAACCTCACATGCTCGAACGCGAGGCGTATCGGCTTTCGGATCCAGCCATCCGTCACCAACCTCAGTGGACACAACGCCTGGTGGGGCAACGGCGCCGTGGATCGTGACAGGTGAATCGTGGGACCGTCCGGAGCCGCTGCTGCCGCAGCGAACTCGGCGGCCAGACACCCATCAGCCGTATCGACAACGATCCGGCTCAATGCACCTGCTCCTAGTGCTGCAATGGTGCGTGCCGTGATGGGCGGGCAGGTCAGGGGTTGTGCCCGCTTCGTTTGTAGAGACTGGTGCGGGCCCGGTGTTATCGTCGCCGACGCCAAGTCGACGAGTGCCAGGTGTGCTCGATGGGTGTGGGCCGGAGGCGGGTGAGGCGGGTGATCAGCCGTTGTCGGCGAGGCTGAGGTGGCTGAGCTGCGAGGGTCCTTTCGCGGCCCGAAGCTTTACGGCCAACGATTCCGTTTAGAACTCCTAACAAAATGATCTTTGAGGTGGGAGGATCAGTCCGGGGGTGTTGATTCGGGGGTGTGGGGTGGCTCGGCCGAAGGAGTGGGAAGTGGACGACCGACTGTGGGCGGTGGTCGAGCCGCTGCTGCTGCGGGTGGAGCGGCGGGCTCGGCATCGGGGCCGCAAGCGGCATCCGGACCGGCTGGTATTCCGGGAGCAATAGTCAAGACTTGTGGATCGGCAGTTGCTCAGCTTCGAGTTGATCGGATCTTGGTGAGTGCTCCGACCGCCGAGAGCTCGTCGCTGAGAGGCTCGTCGGCGGCCGGCAAGGTGATGAGCAGGAGTGTCGACATGTCGGGGTGCTCGTCGTCGTAGAGATCGTCTTCCCCGTCGTCTCTGGGAATGGCGTTCGGCTGGATCTGGAGGCGGGTCGTGTCGGCGAGGGTGGCCAGGAAATAGACGCCGAGGTAGTCGCTCTCGCGTTCGGTGAAGGTCACGTCGAGTCGGTCGGCGAGCAGGCCGGCCAACTCCTTGGCCGTGTAGGAGTTCGTGCCGTAGGCGTCGGAAACGGTCATGTGGGCATTCTCCTCAGGCCGCGTGCCTTTCGGTGCGTTCGACCGGCACGCCGTTCTCGAACCGGGCCCCGGCCCGGACGAGTGGGACCGGGCAGGCTCCGGTTATCGCACACCAGCGGGCCTGGGCGGATTCGACGAGCTTGAACACCATGGCCAGGGCCGCGGCCGGGCTGCCGGCGCCTCGGGTGACCTTGGTCCGGAGCTTGACGGTGGAGAAGGGCTCCGGCCGCTACCGGGGCCGCCCACCGAGAAGTGCATCGCTCCTCGTCGCCCGCCCTGCTGCCAGGCGGGTTCCCGTTCGGCTCCCGCCGGGCTCTTGGATGCGGATTCAGCGGGTGCGTTCGTAGTGGCGGCGCACTTTCTCGCGGTTGCCACAGACAGCCATCGAGCACCAGCGGGCGCGGTTGGCGCGGCTGCGGTCGAGCAGGAACAACTGGCACTTGGTATTGGCGCAGGGGCGCAGCCGGCCGGGCATCCGTTCCTCGGTGCCGGCCCAGGCGAGGACCGTCTCGACGGCCAGTCGGGCGTGCGGGGGGAACCTGACTGCCCACTGGAGGCCGTCCGAAGTGACCTCCGGGATCTGGTGAACCCCTTCCAGCAGCGGGCCCAGCGCGGCGGGCGAAGAGTTTCCGCGCACCACATTCTGCAGGACGTCCCGTGCCTCGCGCAGCAGCGTCAGTTCCGCGAGGCTGCCGTCGCCGCCGTGTTCCCGCGCCCAGCGCCTGCCTTCGGCCGGGTCGCCGAGCGCATCCCGCTCCTCGCCGTTGATCAGCGGCCTGCTGTTGAGCAGGTCCAGTAGCGCACCCATCGGGGGATCACCGCCTTTCTAACCGGATGGAATCGTTTGACAGGTTAGCTCACCCTGTGCTTGCGTAGCGAACGGCTAACCAGATCAAAAGTGCAAAGGGGTTATATATGAGCTCGGTGCACCACCGGACCGCCACCATCGACGGTCACGAGATCTACTACCGCGAGGCCGGCCCCGCCGACGCCCCCGTGATCGTGTTGCTGCACGGCTACCCGACCAGTTCGTTCATGTTCCGGGAACTCATCCCGCTGCTGGCCGACGACTACCACGTCATCGCCCCGGACCACCTCGGCTTCGGCCACTCCGACGCCCCGCCCGCCACGGAGTTCGACTACACCTTCGACGCCCTCGCCGAACTCACCTCCGGGCTACTCGACCAGCTGGGTCTGAACCGCTACGCCCTCTACGTCCAGGACTACGGCGCCCCCATCGGATGGCGCCTTGCGTTGAAGAACCCCGAGCACATCTCCGCCATCGTCACCCAGAACGGCAACGGCTACGAGGACGGTTTCGTCGACTCCTTCTGGGACGGCCTGTGGGCCTACGGGGCGAATCCCGGCCCCGACACCGAACCCGCCGTCCGCGCCGCGATGAGTCTCGAGGCCATCCGCTGGCAGTACGTGCACGGCGTACCCGATCCGAGCGTGGTCAGCCCGGACACCTGGGAGCACGACGTCGCCCTCGTCTCCCGCGAGGGCAACGACGAGATCCAGCTGGCACTGTTCCGGGACTACCAGAACAACCGCCCGCTCTACCCGCTGCTGCACGAATACCTCCGCACCAGCGAGGTACCAGTGCTCGCCGTCTGGGGCCGCAACGACGAAATCTTCGGCCCGGCGGGCGCACGCGCCTTCGCCGGCGACGCCAAGAACGCGGAAGTACACCTGATCAACGGCGGCCACTTCCTGTTGGAGAGCCACCTGGACGTAGTCGTCGGCTACCTCCGCGGCTTCCTCGGGCAGGTGCTGGGGTAGACAGGGTTCGGGGCTGGCAAACGGGCCTTTGCAGGCCACCGTGCCAGCCCCCGACCCGTCCCGGATCGGCCGTACGGCGCTCCCGTCCCCTGCGTGGCTGGAGAGAGCGACGGCGCCCGCCGGCGCTGGTGGTCGGGCCCCTCTCCCTGCCGGGCCCCACACCCCCCCGCTGAAGTACTGCCAGCATCGAGATCTTCCGCAACCTGCGTCAACGGCCTTGAACGCCCAACGCCCCCTCGCTGCACGCCGTCCACGGCCGAGCCACCCCACACCCCCGAATCAACGCCCCCGGACTGATCCTCCCACCTCAAAGATCATTTCGTTAGGAGTTCTTAGGCAGGGCCCGTCGGCCCGGGCGCCAGCAACTTCGTCCCGGAACAGCTGGGCGCCTGCCGCACTGGCCGATTTCATCGCGCTGGGTGACTGAGACGCTTGGCCCCACCGTCCACTGGTCCGGCTGCCGCAGCGGCCTGGCAGGTGCTGCACCGCATCGGCGGGGCCCCCAACCTCGGCGCAGGTGCAGACGCGAGCAGCAGGCCCAGCCGGCGGAAAGCAGCTGGTCGTTGCTCGAGTTCGTCGCGCGCCTGCGCCGAGTTCCCGGGCCAGAATCAGTGTCGGGTCAACCGGCGCAAGGCGTCGAGCACGGACGGCGCGAGCGTGTCCGGGTGGTCGGGGTCGTGCATCAGATGGTCCACTGCGGGCAGCGTCACCCGGCCCGGCCGGCCGGCATACGCATGCCGCAGGGCGTTCGTCAGGGCGTTCGTCGTGGCACAAGGGACCTGGGGATCGTTCGTGCCGCAGGTCAGAAGTACCCTGGTTCCCGGACGGAGTGTGCGGGCGATGTCTGGTGGGTTGACGGCGTCGTCGCTCACCACGAACCGTGCGCTGGTGCCTTGGAACGCCTCGAAGAGCTGGGCGATCTCGGCGGGCAGGTCGGTGGTGTCGACCGGTCGATGTTCGCGCAGAGACGTGATGGCAGCATCGATCGCCGCGTTAACGGTACGTTGCTGCTCCGGGGTGAGCTGGCCCTGCCGGGTTGCCTCGGCGACCTGGGCCTTGAGTTGGAGCGAAACCAGGTCCAGCATGCGGATCGCCTGGGGCTGCAGCAATGCCAGACCGACGGGCCGCGGGCGAACAGTGCCGCCGAGCACCAAGCCCGTCATCGCGCCCTCACTGTGTCCGACGAGCAGCAGTCGGTGCGGGTCGGTCTCGGGCTGATCGCGCAACGACTCGTAGGCGGCCCGTGCCTGGCGGACGAATGCCGGGTAGTCGAGATCTTCCGGGTGGTCCCGGTAGGCACCGAGTCCGGTGCGGCCGGTGCCGTACTTGTCGAACCGCAGCGTGGCGATCCCCTCCTCGTCAAGCGCATCGGTCAACTGCGCCAGGGTGTCCGGTGAGAACGCGGGCGGTTGGTTGCCGTCCCGGTCGGTGGGTCCGCTTCCCGGTAGCAGCAGCGCCGCCCGCAGCCGCTGTCCGGCACGGTGCTCGGGGACATGCAAGGTGCCGTACACGGTCGTACCGTCGGCCGTGAAAACGACCTCGCGGTCGGCGGCGGGCACCAGGCCGGGTGCCGCCTCGGCCGGGGCGGCGATGACGGCGGCCAGTGCCACCACAGCTGCTGCCAAGTAGCGAAACCTCGGCTTACCTTTCCTCATGCGAGAGCCTTCTCGATCAGGGCGACAGCGGCGCGGGGGTCCTCGACTTGAAGCACCAAGCGTGCGTACCGCTCGTCGGCGAGTTCGATCACCACCGCCTTTGACGCATCCCTGACATCCCAGAAAACCTTCTCGCCGTCCTGATGGAATGTGCCAGCGATGATCAGGCCGGGAACGTGGGAGCCCGGCGCGCGGATTCCCTTGGGGTCGGTGGCGATACCGGGATCGGCGGTCACGCCACGGACGTTGGCCAGCGGGATGGTCAGGCTGCCCTTGAACGCCCAGAGCTTGTCGAACCCCTCGATCACGACGACGAGATCGTCGCCATCGATGCGTATCAGTGCCATGTCGGCTTCCCTTTCAGGGAGGTGTGTTGAGGTGTTGGGTCAGCGCGGCGGCAACGTTGTCGGGGTTGCCGCGCAGGAGAATGCCCAGCGCGGTGGCGGTGAGGGCGGCGGCCAGGTCGACGGGAACACCAAGCGCGTCGGCGATCGCCTGGTCGACGGCGGCCCAAGCCGCCGCCACCTCGGAGGCCACCTCCTCGTCGACCGGTGCGCGTTCGACCGTCGCGAGCAGAAGCAGGCTGAGGTCTGTCCCGGTGACGAGTCGCAGCGCGGTCGCGGCATCCGGTGCGCCGCCGAGGGCATCGAGCAAGGGACGAACATCGTCGGCGAGGTGACGGCGCAGAGCGATCAGGTAAAGACCGCGTTTGCTCCCAAACGTCTTGTACAGGCTGTTGCGGTGCACCCCGAGGTGACCGACGAGGTCGTCGACGGACACGCCGTCATAGGCGCGTCCGCCGAACAGTCTTACGGCGGCGCGCACTGCTTCGCCCTCGTCGAATGCTCTTGGCCTGCCCATAGCCACCACAGTAAACAGTTGAGGAACGATCGGTCAAGAACGATCGTTCCTCAATCCTCTCGACGGCGGCGTCGGTGTCCGTCGGCAGTGCATCGAGTCGGTGATCAGAGCAGGTGTGCCAGGCAGGGGGCCTGAGCGCCTGCGCAGCCAGGGCATCCCCGCTCGCCGCCGCGCCCGGGCTCGGAAAGGCATCGCCTGGGAGCGCCTGCTGCAGGAACTCGGCTTCGGGTCGGCCATGACCTGCTGGCGCCGGCTGGCGGAGTGGACCGAGGCCGGAGTGTGGCCCCGGCTGCACGAGGTTCTCCTGGCCGAACTGCGGAGCGCGAACGTCCTGGACTTTCCCCGAGGGGCGGTCGACGGCTCCCACATCCGCGCGATAGAAGGGGGTCCAAGACAGGGCGAAGTCCCGTCCGCCGGGGCAGGGCGGGCAGCAAACATCACCTGGTCACCGAGGCCACCCGCATGCCGCTCCCCGCCACCTTGCCCGGCGGTAACCGCGACGACGTCACCCAGCTCATCCTGCTGCTGCAGGCCGTGCCGCCGACGCCGGGGCAGGTGCGGTCGGCGGCTGCGTCGGCCGGAGGTGGTGCTGGGCGACGGCGGCTACGACAAGTGCCGCCGCATGGTCTGGGACCTTCGGTGTGAAACCGGTGATCGCTCGACGCGGCATCGAGCACGGCTCCAGTCTGGGCAACCAGCGCTGGGTCGTAGAGCGCGCCTACGCCCACCTGTACTGGTTCCGCCGCCCCCGCATCCGCTGGGAGATCCGCGACGACATCCACGAAGCCTTCCTCACGCTCGGATGCGCACTCATCTGCTCGCGACGCCTGAAGTCATTGCCTTAGGGCTTGCCGGGAAACAAGTCGTGGCTTCCAGCTCTGGGGCTCGTTGGTCTGGTATGGGGAGATCGGAGAGGATCGAGGCCGTTCTGGCGGCAAAGTTCCAGGTGCTGTTGCCACATCTGGACGAGCGTCAGCGTCGGCTGGCTATGGGGGCGGAGGCACTGTCGCTGGGGCATGGCGGCATCAGGATCGTCTCCGCATCGGCACCGATCACGACACGGCGGCGTTCGCCGTCGCCTCGATCCGCCACGGGTGGCAGGCGGTCGGTCGGCACGACTACCCCGGCGCCCGCCGGCTGCTGATCACCGCTGACGGTGGCGGCTCCAACGGCTGCCGCACCCGGGGCTGGAAGACCCAGCTCGCCGATCTCGCCGCCGAGACCGGCCTTGAGATCACGGTGTGTCACCTGCCGGCCGGCACCTCGAAGTGGAACAAGAGCGAGTACCGGCTGTTCTCCCACATCACCATGAACTGGCGAGGCAGGCCCCTGACCAGCCACGAAGTCATGCTCCAGACCATCGCCGCGACCACCAGCCGCACCGGCCTCACCGTCCAGGCCGAATTCGACAGCGGTGAGTACCCCACCGGCGTCCGCGTCAGCGACGACGAGATCACCGCCCTGCCCATCACCCGCCATCGCTTCCACGGCGACTGGAACTACACCCTCCACCCCCAGCGTCCGACGGGCACGGCAACCACCACCAGCACACAGGACGAGGCCCAGCCGGACGGACCGGCCCGCCTCACGCGGCGTTCGCTACAGGACCCGGAACTGACTGGGATGACCCGCCGGCAGCTCAACGAACTCATCGACGTGCTGACTCCAGCGATGGAAATTCAACGCGAGCAAGTGCTCGACACGCGCAGAGGCCACGGACGCCTGGTGGCCCCTGGCACAGGAGCCAAACCCAAGCTCACCTCAGCCGACCGGGTCCTGGCCACCGTGCTCCACCTGCGGAAACTCGCGACCATGATCTCCTGGGCCAGCTCTTCAACGCCACCGCCACGACCATTAGCCGCGCAGCGAAAGACGTCCGCCCGCTCCCGGAAGCCCACGGAGTTCACATCCCTGCCTCGACCGCCCGCTTCCGCACACCGACTGACATGACGAGATTCCTCGGCCTCGACTAGAACAAGATCAAACCGACGTGTTGATTCCCGACAAGCCCTTAAGAACCCTAACGAATGATCTTCGAGGCGGTTGGATCGCTCCAGGAGTGTTGATCCGAAGGTGTGCAGTGGCGTGGCCGAAGCCGTGGTACGTCGACGATGAGCTGTGGGCGCTGATCGAGCCGCTGTTGCCCAGAGTTGAACGCCAGCTCCGGGCAACAGCGGCTCGATCCCCCACGGCAGATGAGAGGTTCGGGCACAGTGGCCGGCTTGAATGCCGCCGGTTTGGACGGTCGGGGCTGCGACGACGCTTGTCTCTCACGCCAGAGACCCATCTGTCATGGAACAGACGGCACCTCGGCGCCCACGCGGTCCGGCCGCCGTTGCGCCTGCCAGCTTCCTGATGCAGCACAGCACCCCGTAGGGAGAGTGTCAGAGCCAGGGGCCGGTTCTCAGATGGGATCCGGGAGGGTTTGGGTCGCGACATCGGTGATGGTCTCGATCGCTTCACGCAGGCGCGGGGCGCCCCGGGCGCCGAGGCGGGTGACGGCGGTGATGCGGCGGGCCGGGGCGGGCTCGCCCCGCAGCGGGATGCGTACGACGGGCTCGTTCTCGCGCAGCCGGGCGAGGCGCGGTACGAGAATCACGCCGAATCCGTGGGCGACCAGCGCCGTGCCGGTGTCCCACTCGTCGGCGTGGTGGGCGATTTCGGGCGTGAAACCGGCACTCAGGCAGGCGGCGAGTACCAGCTGGTGGTAGGTCGTCCCTGGGTTGCCCACGATCCACGGTTCCGTTGCGGCGTCGGCGAGGGTGACCTGCTTGCGCCGCGTCAGCGGGTGGTCTTCGGCGACCACCAGGTCCAATGGGTCGTCCAGCAACGCGTGCTGGTCGAAGCGCCGGTCCGTCATGGGGGGCGAGTCCGCGGTGACCACCAGCAGGGCGAGGTCGGCCTCCTCGGAGAGCAGCAGATCGAAGCAGCGGTCCGGCTCCGCCTCCACGATGCGGACCGTCAGGCCCGGATGGCTGCGGCGCAGAGTTGCGGCCGCCGGAGGCAGCAGCCGGCTGGCGGCGGTGGAGAAGCCGCAGAGCGTCAGTCGCCCCGGACGAGCAGGGTCGGCGGTTGCCAGCTCAGCCTGAGCCAGCTCCCACTGCTCGCGCAGGCGTTCGGTGTGGGCCAGCAGGATGTGCGCCGCCTGCGTGAGCCGGATGCCGCGACCTTGCTGCACGACCAACTCCACGCCGACGTCGGCGGCGAGTTGGCGCAGTTGGTAGGAGACGGCCGAGGGGGTGAAGTGCAGCGCGTGGGCAGCACCCGTCACCGTGCCGTGCTCCGCCACCAGCTGGAGGACGCGCAGTCGCGGATCAATCATGAAACAATCTTGCATGATCCGCTGCGCGAACGTTTGATTTTCTTCGGCGTCTGGGCGACGCACACTGGCACATGTGACTGATCTGAGTGCTTCGGACCCGGCGTTCCCGGACCACCGCATCAGGCGTGTGATGCCCGTCCGGCCTCGCCCGCGTCGTTCCCTCCCGCGGACATACCCCACCGACCGCCACACCGTGCGGACCGCCGCATTGCTCGTGGCGGTACTGACCCTCGGCGCGTATCTGCCCAGCCCCCTGTACCCCGACTATCAGCGGCTGTTCGGCTACGGTGATCTGGGCACCACGCTGCTGTTCGCCACGTTCTCGCTGGTCAGCGGTCCGGCGCTGCTGCTGTGCGGCCCGGCGGCGGACACGGTCGGTCCCCGGCCCGTGCTCCGTCTGAGTCTCCTGCTCGCGGCGGCCGGCTCGGGCTGCTTCCTCCTCGCCGACGACATCGTCTGGCTGTTCGCCGGACGCGTCGCACAGGCGCTGGCCCTGGGCGCCTCCACGGGCGCGGCCCAGGCGCTCATCACCCGGCATCTCGGCCCGGCGACTCGCCTCGGCGGCCCGCTGCTGGCTGGCTTGGCCTTCGCTGCCGGTACCGCCGCCGGGCCGGCCCTCGGCGGTGTCCTCGCTCAGTACGCCCCCGGGCCTCACCTCACCCCCTACTTGGTGCACCTGGTCCTGCTCGCATGGGTGGCGGTGCATCTGCACCGGGCCACCCCAAAGCCGACAGCACCCCGCGGGGCGCTCCGCCGGTGGCGGCCGTCCCGGCCGCACATCCCGCGCGCCGCCCGGTGGTCGTTCCTGATCGCCGGTGCCAACGGGTTCTTGGCCTGGGCCGTTGTCGGCATCTACCTGGCGCTGTTGCCGTCGCTCCTGGCCCGTACCCCGCACGGCGGCGGCCCCGCCCTCTCCGGCGGGGTCCTGGCCATGGTCCTGCTCTGGTCAATTCTGGCCCAGCTTGCCGGTGCCCGCGGGAGCGTGCGCGGGGTCCAGCAGACCGGCGTCATCGCCCTGATCGCGAGCGTGCTCCTGCTGGCCGCCACCCAGGCGGCGTCGCTCCCGGCCACCCTCGGCTCGGCGCTGCTGGCCGGCGCCGGACACGGACTGGCCTACAGCGGCGCCACGCGGGCGGTGGACGTCCGAACACCCCCCGAGCACCGTGCGGGGGTGGGCTCCGCGCTGTACCTGCTCTTCTACCTCGGGTCCGGCGTGCCGGCCGTGGCCACCGGGCTGATGGCCACGTGGATGTCACTGCCGACCGCCGTCACTTTGCTGAGCTGGGCCGCGGCCGCCTTCGGCGCCGTCGCTTTGACGGCCACCTCCCTTAATGCGGGTGCCACCGGCCGACCCCAACAGGGCACCCCCTGAACCTCTGCGGGACCTGACCTCTCGGTCTTCGCCAGCTTCGGCGGCCAACTCCTCGCTATGCGGTCAGGGGATGTCTACTCCTGGGCCTGTCGACGAAGGTTGTCCATCTCCTCCCGGCGTCAGGTGAATACGGTACGGAAGCGACGAGCCGTGCTTTCGAGCTCTGTGCACCAGTGCGGATGCCGTAGCCCGACAGCTCCTTCTCCGGCCCGGAAGAGCGCATCATGCCGCGAGGGCGTAAGCCCCTCACTGCGCAGCCCGTTCGAACTCCTCCCGACTGAGCGCGCGGTGAGGCAACGGGGTGGGAGCCTCGCGGTTCGCGCGAAGGCCGTCGAGGATCAGGGTGAGGTAGCGCTGCCAGAGGTCGGGGGAGACGTCGCGGCCGTACTGGGTCGCCGTTCCGAGCATCATCTGGATGAGGGGGAAGTCCGTCACCTCGATGTCGTCGCGGAGAGATCCATGCCGCTGGGCACGCTCGATGACGGCGCTGATCGCGGGCGAGAGCCGGTCGCGCGCATCGGCGACCCGGCTCTTCCCGTGGGTGCCGACGAGCAGGACTTCTCTCAGGCCGCGGTCGTCGGCGAAGTCCTGGCCGGCCGTGGTGAAGAAGTGGACGAGCCCGTCCCAGGGGTCCGTGCGGGTCAGAGCCTCTTCCGCGACGTCGATGATGCGCTGGATCTCCTTGTCGAAGATCGCTTCGACAAGGTCCTCGCGGTTGGCGAAGCGCCGGTAGACCGTGCCCACTCCCACGCCGGCGTGATGGGCGATGTCGTCGAGAGTGACGTCGATCCCACGCTGCGCGAATACCTGCTGAGCTGCGGCGATGATCCGCTGACGGTTTCGTTCCGCGTCGGCGCGAAGAGGGCGGCCGGGGGTGCCGCCAGAAGGCGGGCCCGGGGCGGTTGTGCGGCTCATGCTCCCAACTATAGGCCCGTATGTGGAGATGGTGTCTCCGCTTGGTGCTACGGTGGAGGCCGCAAATGGAGAGATCTTCTCCACTTTCATCGCGCCCCATGGAGATTGCTGTGACAGCCGTCACCAATGAAGTACGCCCACCGCGGGCCGATCGGGCACCGGAGCGGCATCATGGCCGTCGCTGGCTGATCCTCGCCGTCATCGCGATAGCTCAGCTGATGGTGGTGCTGGATGCCACGATTGTGAACATCGCCCTGCCCTCCGCGCAGGCGGACCTGGGCTTCTCGAACGACAGCCGCCAGTGGGTCGTGACCGCCTACTCACTGGCCTTCGGTAGCCTCCTGCTGATCGGTGGGCGTATCGCCGACCTGATCGGCCGAAAGGTCACCCTGGTCATCGGCCTCGTCGGGTTCGCCGCGGCCTCGGCCGTGGCGGGCGCCGCCACGAACTTCGAGGTGCTGGTCGCCGGACGCGCCCTGCAGGGGGTCTTCGGTGCTCTTCTGGCTCCGACCGCGCTCGCCCTGCTGACCACGACGTTCACCGACGTCAAGGAGCGGGCGACCGCCTTCGGAATCTTTGGTGCGGTCGCGGGCGCGGGCGGCGGTATCGGCCTGTTGCTGGGCGGGGTGCTCACTGAGCACCTCAACTGGCGCTGGTGCCTGTACGTGAACCTGATCTTCGCCGCCGTCGCGTTGATCGGCGCCCTGTTCCTCCTGCCACGCCACCGCCCAGACAAGAGCGTCAAGATCGACCTCCCCGGCACGGTCACCGCCACAGCCGGTCTGTTCGCCTTGGTCTACGGTTTCGCCAACGCCGAACACGAGGGCTGGAGTTCGGCCGGGACATGGGCATTCCTGGCCGTCGGCGTCCTTCTGATCACGGTATTCGTCCGGATCCAGGCCCGCGTCGCCCACCCGCTGCTACCTCTGCGGGTCCTGCTCGACCGCAATCGCGGCGCCGCCTCCATCGCGATGTTCATCTCCGCCGCCGGAATGTTCGGCGTCAATCTCTTCCTCACGTACTACCTGCAGCAGACCTTGCGCTACTCGCCGGTCGAGACCGGCCTGGCGTTCCTGCCCATGGTTGGCGCCGTGATGATCGGCACCACCCTTTCCTCCAGCGTCCTCAACCAACGCTTCGGCCCAAAGCCGATCGTCCCGATCGGCATGGCCCTCTCGGCCGTCGGCCTTACCTGGCTCACCGGACTGGACGCCTCCTCCACCTACGCCGCCCACGTCCTGCCGCCGCTGCTCCTCTTCGGCCTCGGCATGGGCCTGGTCATGGCGCCGGCCATGAGCGCTGCGACCTCCGGTATCGACCCGGCCGACGCCGGCGTCGGCTCCGCCAGCGTCAACACCATGCAGCAGATCGGCGGTTCCATCGGTACCGCGCTGCTCAGCTCGCTGGCTGCAGGCGCCGCCACCGACTTCCTCGCCGGCAAAGAGGCCACCCCCGACCTGGTCGCCCAGTCCACCCTGCAGAGCTATTCCACCGCCTACGAATGGTCAGCGGCCCTCTTCGCCGCCGGGATGGTCATCTGCGGTCTGCTCTTCCGCCGCGGCGCACCGGTCCACGACCCCCGCGCCGCCCACACCGTCCACATGTGACGAACCCCGCTGACTATCGGTGCCGGGTGTCCATGAAGGCCAAGAACCCCGGCCCCCCCACACACACAAAGGAGCCCCTGATGAACAAGCCCCGCGCCCTGATCGTGGGCATGGGTATCGGAGGACTGGCCACGGCCATGCGTCTTCACGAGATCGGCTGGGAACCCGTTCTCGTCGAGCGCTCACCCGCACGACGTGCTGCCGGATACTTCATCGGCTTGTTCGAAACCGGCCGCGCCACCGCCGAACGGATGGGCGTCCTGGACGCCATCGGAAACCGGACCGACCCCGCCAGCGTCACCTACGACATCGACCGCGAAGGCCGCCGCCGGCCCGGTATGGGCTACGGCGACCTTCCCGGCGAGCCGCGCCTCATACTGCGCGGGGACATCGAAGCCGCCCTCTACGACCAGGTCGCCTCGAAGACCGAGATCCGGTACGGCACCACACCCCTCGCCCTCGACGAGCACCCTCACGGTGTGGATGTCACCCTGGCCACCACCACCGGCGAGAACACCACCGAGACCACCGAGCGCTTCGGCCTCGTCGTCGGCGCCGACGGGCTACGCTCCACCGTCCGACGCCTGGTCTTCGGACCGGACTCCGACTACCTGAAGCCCTTCCACCACATCATCGGCGCCACCGTCCTCAAGGAAGCCGTGCCCGGCTTCCGGCCCAACGACGGCCTGGTTCTCGCTGAGCCGGGCCGCTCCGTCTGGGTCTTCCCATTCACCGACCACCAGCCCGGCGTGCTCTTCAACTACCGCACCGACGACGAGGACGCCCAGTTCCGCCGCCCTCCTACCGAGTCTCTACGTTGCGCCTTCGGACCCGAGCCCACCGGGCCCGTACTGGAGAACCTGCTGACGCAATTCGAGCATGCTGACGACGCTCTTTTCGACTCCACCCACCAAGTGGTGATGCCGACCTGGCACACCAACCGCGTTGTGCTCCTCGGTGACTCCGCCTGGTGCCTGACCCTCTACTCCGGTATGGGCGCTTCCAGTTCTCTGGCCGGTGCCGACTTCCTCGGAACGACCCTGCAGCGCAACCCCGACAACGTTCCGCGGGCTCTGCGAGAGTACGACCAGAGGTTGCGGCCCTTCATTGCCACCCAGCAACACCTCGGCCGCAAGGAGGGCCTGCCGATGTTCGTCCCCCAGACCCGCCGGGAAATTACCACTCGCAGCCTTATACAGAAGCTGACCAGCAACCCGGTCGGCAAGCGTGTGATGAAGACCGTCATCGCCGGCAAATTCAAGAGCAAGTCCCTCGACATCGCCGCCCCCTGACAGAGCTGGCCAGCGCCGCCCACGACAACGCCAGGCTGCCAGCTCGGTCAGGGCCTGCTTGCGCCAGCGGAAGCGTGCACGGAGGCGGCCCTGACCAGGACGGTCAGGGCCAGGCCGAGGGTGTCGGTGATCAGGTGGCGCTTACGTCCTTTGATCTTCTTGCCGGCATCGATGCCCTGGCTGGTCTCGGCGACATTGAGCCCGTCCGAATGTCACCAAGGTGTATGGGCCGATGGCGGCTACAAGACCAACGTCATCCAGCACGGCTCCGGCCTCGGGATCGAGGTGGAGTGGTGCGGCGACCGAAAGAGAAGGGCTGTCAACCGTTGCCCAAGCGTCGGGTGATCGAGCGGACCTTCGACTGGCCGATCAGGACCGCCGCCTCGCACGTGACTACGAGGCCCTGCCGCAGAGATCCCGAACGATGATCCACTGGGCGATGCTAACGAAATGAGCCGCGAACTCACCGGGGGATCCGCACCAAATCGGCGAACCGAAACAGGCTTATCACCCACACCGGCATAATTGTTGATCAGGTGCCCTCTGAGGCTTCCCCCATTAATGATCTACGTCGTGCTGGTGGACCAGTACCGTTCACGGTCGGCGAGGGTGAGCTGGCGGGTGCTGGCAATGCCGCGCACGGCATGGTGGACGCCGTCACCTTCAAGGTGCCGGGCCAGAGGAAGAACCCACATCTCCAGGCCCCGTCTGGCCCCGCACCGGATTAACGTGTTGTTCGCGATGCTACGCGACGGTATGTTCTACGAACCCAGCACCCCCACGCCTCACTTGACGAAAGACACAGAGGCACCCCTATGCTTCTCAGGCGCCCCGTAGGGCTCCAGGGAGTCACGCATGCGCACGACATCTTTCGGCGGCCCGGTCGGGGCAGTGGCGGCCGTTCCTCGGCGGCCGGAGTGCAGCACTCCCTGCTCCTCACAGTGCCGCAGCAGACGGGCCCGACCCCCGAAGGCCGGGAGGGCTCACCGACCCCACACCTGGCCGCTCCTCACGCCGGAGCGAGATGTCACCGCGGGGGTGTGTCCACGGCGATGTCCACCGCCGTGTTCTTTTCGGCGATGGCCCAGCCAGCGAGGAAGGACAGGGCCTGTGCCGAGCGGGAGTGCGGTTCCGCCGTATAGGCGAGCAGGGTCTGGTCCCCGTTGCCACGGACGTCCATGACCTGGAAGTCCAGGGTGATCTCGCCCGCCAGGGGGTGGAGAAAGTCCTTGCGACCCGAGCGCAGGGCCCGCACCCGGTGGGTGGACCACCACTGGCCGAAGTCGGCGTCCTTCACCGACAGCTCACCCACGAGACGGGCCAGCGCGGGATCTTCCGGGTAGCGCCCGGCGTCCATCCGCAGGTAGGAGACGCACTCGCGGGCCACCTTCTCCCAGTCGGTGTACAGGGCGCGGACCTTCGGGTCGAGGAAGGACAGCCAGATGTGGTTGCGGTGCTGGACGGGCACCTGGCCGAAGTCGGTGATCAGGGCTGCGCCCAGGGTGTTCCACGCCAGGATGTCCATGCGCCGGCCCAGCACGAGCGCGGGCACCCCGGGCATGCTGTCCAGGAGCACGCGGGTGGCCGGCGACACCCGCTGTGCGCGTGGAGCGTGAGAGTCGGCCTTGTTGGTGAGGCCGGTGGAGTCGGCTGCGCAGCGAAGCAGGTACTCCTGCTCGTCCGTGCCCAGGTCCAGGGCCCGCGCGAGGGCAGTGAGGATCTCCGGCGACGCCGACTTCGCCCGTCCCTGTTCCAGGCGGATGATGTAGTCCACGCTGACACCGGCCAGCGTGGCCAGTTCCTCGCGCCGCAGTCCCGGCACCCGACGGTGGCCGGAGGAGGGGAGGCCGGCCTGCTCCGTGCTCACCCGGGCCCGGCAGGCGCGCAAGTACTCACCCAGTTCGCTCACAGGTTCTCGTCTCCTCATCGGTCTCGCACTATCAACGCGGCCGTGGTTCCCGGCTGGCTTCCCCGGGTGGTGCGGCCACGCCACCACCCGGGGATGATCCGTAGGGCTCATCGGTCAGGCCGGGTTGCGGGTGTCGTCGTGGTCGGTGGACAGGGCCAGATCGCGCCAGGCGGCGGACTCCCTCCGGAGCTGGCCGATCTTGCGGTCGAGTTCGTCCAGGCAGTCGCTGCCGAGCTGAGCGCGCACCGGCGGGTTGTCGGCGTCGGCGAGCGCCAGGACGGCAGCGGCCCCCTTGACCGGGTCGCCCGGCTGGGCCTTGTTGAGTCCGGGGACCATTTCGCGCACCGCACCAGCGGTGCTGGCGTAGTCAGCGATGACCTGGTCCTCGGTGTGCAGGCTGGTGGCATCCAGGAAGTCGGTGCGGAAATAGCCCGGCTCCACCAGGATGACACCGATCCCCAGTGGGGCCAGTTCCTGTTGCATCGCCTCGGAGATCCCCTCCACGGCAAACTTCGTGGAGCAGTAGATCCCGAACCCTGCGGAACTGCTGAATCCGCCCAGCGAGCTGATGTTCAGGACGCGACCGGACCGCTGCCGACGCATCACCGGCAGCACCGCGCGGGAGACGTTGAGCAGGCCGAAGACGTTGGTGTCGTAGATCGACCGAACCGCAGCGTCCGTGGACTCCTCCACCGCACCCAGCAGACCACGCCCAGCGTTGTTGACCAGCACATCGATCGCTCCGAACGCCTCCACGGCGACCGAGGCCGCCGCGCGAGCCTGAGCCTCGTCGGTCACGTCGAGCGCAGCCGGGAGCAGCCTATCCTCGTAGCCGGGCAGCGCCGTGCGGATTGCTTCTGGGGTGCGCGCGGTCGCGACGACGTTGTCGCCGCGGTCGAGAGCCTGGCGGGCGATCTGCAGGCCGAAACCGCGGGACGCGCCGGTGATGAACCATGTGGTCATGCTGCCTCCTCGAACAAGGGGACGCGGCGTCCCCGAAGATGCTGTGGTGCGGTGGTTTTATGCTGGCTGGAGCGCGCGGCGTCATCCAGGGAAGGAACTCCATAGGAACGGCCTCCCCCGTGCACGCCGGGTCGTCAGCTGCTGCGGATGACCTTGGTCTCCAGGTACTCGCTCATGCCGTCAGGCCCGAACTCACGGCCGTTACCGGACTGCTTGTAGCCGCCCCACGGAGCCGACCAGTCGAACTCGGCGTCGTTGATCAGGACGTATCCGGCCCGGACGCGCTCCGCGACCAGGCGGACCATCTCCCGGTCGCCGCCGGTGACGTATGCCGCGAGACCGAAGGGGGTGTCGTTGGCTATGGCGATCGCCTCGTCCAGAGAGTCGTAGGCGATCACCGACATGACGGGGCCGAAGATCTCCTCGCGGGCGATGGCCATGGTGTTGTCGACGTCGGCGAACACGGTCGGCCTGACGAAGTGCCCCGACTCCAGCCCAGCCGGCTTACCGAGCCCGCCGGTCACCAGCCGTGCCCCGGCGTCCAGACCCTGCCGGATGTAGCCCTGGACGGTCTTCCACTGCTCGGCCGAGATCAGCGGGCCCATGGTAGTGTCCTCGGCCTGCGGGTCACCCAGCTTGAGTGCCTCCACCGCCGGTACCAGGACGGACAGGAACTCCTCCAGCCGCTCGCGAGGTACCAAGGTGCGGGAGGGGGCGCTGCACAGCTGCCCCGTCATCGCCATCAGCCAGGTCATGGCTGTCTGCACCGCGATCTCCAGATCTGCGTCGGGCAGCAGGATGTGCGGGGACTTGCCGCCGAGCTCGGAAGTGACCCGCTTGACTGTCGGCGCGGCGGCCACCGCGACCTGCTCGGCCGCAGCTGCGGAGCCAGTGAAGGAGACGATACCGACCCCCTCGTGCGAGCTCAGCGAGCCGCCGATGGCCGAACCGCGGCCGTTGACGAGGTTGAACACCCCCGCCGGGACCCCCGCCGCGTCCATAATCTCCGCGAGAATGACCGCTGAGTACGGGGTCAGCTGGGCCGGCTTGAGGACCACGGTGCACCCGGCGGCCAGCGCCGAGATCGTCTTCCCCGTGGGCTGCAGCACGGGAAAGTTCCACGGCGTGATCAGCCCCGCCACCCCCAGCGCCTCCTTGCGGATCTCCGTCTCCCCCCGCATCTCCGAGAAGACGTACGTCTTCAGCACCTCGATGGCCGTCGCGATCTGCACCCGGCCGGTCGGTACGTGCGCACCGCGGGCCAGCGCCAGCGGCGCGCCCAGCTCCGCAGTCACCGCCTGCGCCAGATCCTCTGCACGCCGATCGAACTCGACCAGGATCCGCTCCATGAGAGTGATGCGCTCCTGCACGGTGGTCTGCGAGTACGACACAAACGCACGCTCGGCAGCGGCGACGGCGACATCGACATCGGCCTCGCCGCCCAGCGCCACCCGTCCAGTGACCACCCCCGTCGCCGGATCCTTCAGCTCCAGGACCGACCCCTGCAGCGGGGCCCGCCAGGCGCCGTCGATGTACAGCTCGTTGTGCTCACGCATGATGATCAGCCTTCGGTGAAAGGAACCGGGGCCGCACCGTGAACCGTTGCCCGGCACTCCACACCCTGGTTGATTCCCACCATGGAGCCGGGCCACGAAACCCGCCAGGGACACCTTTTCCCATGCAGACCCTGGCTAGGAAAGCCAAGGCCGCTGACGAGACCAGCGACCTGAGCGGCCTCGTCGGCATGTTCATCCGCCGGGCTCGCTCTCTCGCCTCTTCCCTCGAGGCCGATCCGCGCTTCCCCTCCTCCTTGATCCTCCACCGGAGCACCGGAGAACTGCTCGGCCCCCGGTACCTGGGGGCCCAGGATATCCATGCGCTCGACTCGCACTTCGGGTCCGTACTGGAGCGGCTCACCGAACTTCAGACGGCAATCTGGCGCATGTGTCCTGCAACTCCACCGCTCAGCGCTGGATGGTGGACTTGACCTACGACCGTGACCCCGGCGCCACCCGGTTCTACGACCACGCGACGGGACAGACCCGCCGCCTGTTCCGTCCGTTCCCCACCTCGACCCGAACGAACTGGCCGCCGTCACCCCGGTCGCCATCCCTGCCCGCGACGGCCTCGAACTGCCCTGCCATCTCATGTTGCCGCTCGTGGGAGAGGGCCGTGCCCTGCTGCTGGTTAACGGAGGCTCGTGGTCTCGCGACAGCTGGTGCTTCGACCCGGAAGCGCAGCTGCTTGCCAACTGCGGCTACGCGGTGCTCCCGGTCAACTTCCGCGGCTCTACCGGATACGGCAAGGCTCACACGCAGGCCGCGATCGGCCAGTTCGAGGGCCGCATGCACGATGACCTGACCGACGCTCTCGACTGGGCTGTCGGACAAAGCTATGCGGACCACGACCGCACCGCGATCCTCGGCTGTTTCTATGGCGGCTACACGGCGTTAGTCCGTGCCTTGTTCACGCCGGACTGGTTCGCCGCCGCGGTCAGCTATACCGGGATGTCCGACCTTGTGGATCTTGGCCGGTCCGTGATTCCCATCGCCCGACGCGCTGTCAAGAGCAGCTACCTGCGCTACATCGGCGACCCCGACGCCCCCGCCAGGAGGTCGACATGCTCGCCCGCCTCGCCCATCGGCCGGGTGGACGACATCGCCGCGCCGATGCTGCCGATGTACGGCGCCAGCGGCGTGCGGGTAGCTCGTCGGTACTCCGACCGCGTGGGCGAGGCGCTCCGCTCTCGCGGCGCGGAAACCGAAGCCGCCCGGGGTGCCGACGGTGGTGTTCCGGAGCGGGTGGCAGCAAGGGGTGCCACCCGCTCCCACAAGTTGTCAGGAGAAGATCAGCACGCGTCCGGGCGCTTTGCCGACCAAGACAGCTGCGTGCACGTCCCGCAGCTCAACGCACTCTGTGATCGGCAAGTCCGCGCAGACCGTGGGTGGTACTGACTGATCGCCCCATCACCGAGGTGACCAGTCAGTAGCCGTAGATCATCTTGTACGCCACCTCGGGCAAGAACTGCCCAGGCGCAGAACCGGCACCGACTCCGCAGTCACCATCGGACTCTCCGGGAGTTTTCAGCCACAGCAGCATTTCGGCGCCGCCGCCTGTCTGGCTGGCGGGGCCCGTCTTGCGTCCGCCCGGGTTGCACCACTCGCCGTTGGAACCGTGCCCGTTGCGGCTGGTGTCGATGACATACGGCTTCGTGTAGCCGTAAGAGGCAGAGAGGGACTGGTTGATGGCGTTGCCGTAGGCTGAGTTTTCTGTGGTGCTGAAGTAGTTCGAGATGTTCAGCGAGAAGCCGTGCGCCTGCCGGGCACCCGCGCCGTCGAGGTGTTGGGCCATGGTGGTAGCGCTGATCCAAGCCGGGTTTCCGGCGTCCAGGTAGGTCCATGTGTTGGGCGCGTGCGCGTTGAACTGGGCGAGCGCGTCTTTCAGCATGGCGTTGCGCTCGGCTATCTGGGCCTGGCTCAGGCAGCTGAAGTCCCCCAGGGAGTCGGGCTCGACCACCACCAGCGCCGGCCGCGAGCCGATGGCCGAGGCGAATGCTGAGATCCAGGAGCGGTACGCGTCCGGTGTGCCCGCCCCGCCTCCTGAGTGGCCGCCGCAGGCGTCACGCCCGGGAATGTTGTATGCGATCAGGACGGGCAGCTTGTCAGCGGCGTCCGCCGCACCCACGTACGAGCTGACAGCCGAGCCGATGTCCCCGCTCCAGGAGCCGAACCATCGGGCCATAGGCCGCGAGGCTATCTCGCTCCGAATCGCGGAGGCCCGGCCGTCATCCGGGTGCTCAGTCGCCCACACGGCGGGCGTCGAGTCCGGGTCGACGTAGTACCCGCTGGTCATGCCGATCGGATCGGCCTGAGCGGAGGCAGCGTCGGCCCGCTGCGTGAGTGTGAGGGGGAGTAGCAGACAGGCGAGCGCGGGCGCGGAGAGCGCACGCAGAAGTCGCGTGGGGGTCCTCATGGAGGGTGACCTTTCCGTGGGAGCGCTCCCACCTTGCGGCAGGAGGATACGGGTGCCGCGTGGGGGCTGGGGGGGCGGCAAGTAGGGCTGTCGTCCGCTACTGACGGTGGGACGACAAGCGGGAGAGTGTCAGTGAACCCCATAGCTGTCAATGGGGTGTTACTGCCAGGTGAGTCTTCCTCGCACTGCTCGCCTCGCTCGGCCGGGACCACGCGCCGAGTTACCACTGGGCCGATCGGCGAGAACAGGTTGCACAAGGACTCGGGGGCGCACCCGCGCTGCGAGGCCGGCCCTCTGATGACCTGTGAGAACGCATCTCCGCCGCTGCCGCCTCGTCCACCACGGGTGCCAGTAACCCGGCGCCCGTCGCGGGCGACCGCTTTCCCCTGCGGGGCATCGTTTACGCGCTACGGAAGAACGTGAGCCAAAGAAGCGTGGCTGCCGAACGAATCGGCTGCGGTGATGTGACGGCCAGGCAGCGTCTGCGGGCTGCGAAGCCGACATCTGGCCCGCCTGTCCGAGGCCCCGGCCGAACTGCGTCGAAGAAGATCCTCCTCCGTTTCCGGCTCACTCGTCTCGAATCACGATCGTCTGGGCCGATGCGCGGGCAAGCTCGTGACCTGGGTAAAGAAGCGCGTCGACTTCACTGCCAAATGGTCACTGCCCCAGGGACACTTTCGCTTTCATCGTCCTGCCCCGCCACCGGTCGCAGTGAGGTCGCTGGCCTGGACGATGCGTGCCCGTGCGGGGGACTGGGAACGCCCGAATCAACGCTCCGAGACTCTCATCACCAGGGCGGCCATCACCATCCTCCTGACCCGCCGGATCCGAGCAGGGCAGGCAGTGACGCACCCCGGCGCGGGGTACACGTGAGGCAGTGGGGATCCGCCTGGCCCACTGTGTACGGCCGTCTACGGAAGGTCGGGCATGTCAAGAAGCGTGAGCATGGCAGGGAGGAGGTTGCTGTTCAGCGGGTCAGGACTGCCGCTGTCGATGGCGCCTTCCAGTGCGAGGGTGGCGTATCCGTGGACCAGGGACCAGACAGCGTAGCTGGGGACCAGCGCGGGGTCGGTGTCATCCGCCGGTTCGGCGTCCTCGCCGCGCAGCGCATGGTCCAGTGCACGGAGGGCGCGGTGTTTCTGCTCAGCCAGTTCGGGCGCGGTGAAGTCGAACCGGGTCATGCGCCACATCAGGTCGAACAGGGCGCGGTTCTCGCCCGCGAACGAGACGTACTGCGTGGCGACGCGCTGGATGCGCTCATGGACGGAGAGCCCGGTGAGGTCGAGCCCTTCCAGCCGGTCGCAGAGTTGCCGGTAGGCGCTGGTGGCGAGGGCGCCGAGGAGGCCGCGTGTGTCACCGAAGTGATATTTAGGAGCGGACTGTGACACCCCCGCGCGTCGCGCGGCTTCGCGCATGCTGAACCCGGTGACGCCCTTCTCGGTCAGCACCGCGAGCGCACTATCGAGCAGCGCGGCGCGCAGATTGCCGTGGTGGTAGCGGCCTCCGGTGGAAGTGTCCTTAACCATCCCTCCATCTTGACGGTGAGTAGATGGTCCGTAAACTGCTCACTGTCAAGATGTGGAGGCGGGAGCGGGAATGACGGACAAGGTGCTGGTCACGGGTGTGTCGGGCTTCATAGGAGGCCACTTGGCAGCTACGTTGCTGCGGCGCGGGTACGCGGTGAGGGGTTCGGTGAGGTCCCCCTCCCGAATCGGTGAGGTGCATGACGCGATGGCGGCAGCGGGCGTCGGATCGGCGGACCTCGAAATCTGCCGGCTCGATCTACTATCCGACCAGGGGTGGGCCGAGGCTGTCGAGGGGTGCCGGTACGTTCTGCACGTGGCGTCCCCGTTCGTACTGGAGAAGCCGAAGAACCCCGACGACCTGATCCGCCCCGCCGTCGAGGGTGCGACCCGGGCGGTCACAGCGGCCCTGGACGGAGGCGCGGAACGCGTCGTCATGACGTCAGCGCTGGCAACGATGCAATTCGCCCGCGCACCCAAGGGGCACCTCTACACCGAGGCCGACCGGACCGACCCGGACGACCCGCGTCTCAACGCGTACACGGTCTCCAAAATCAAGGCCGAGCGCGCCGCGCTGGAACGCGCACAGCGGTACGGAGCCCCGGAGCGACTCGCTGTCGTCAATCCTGGCGCGGTCATCGGGCCACTTTTGACCGACGATCCCGGAACCTCGATCACAGCGATCCAGCAGATCATGTCAGGCGCACTCCCGATGATCCCCGACCTCCGGCTTCCCTGGGTCGACGTGCGAGACGTCGCCGATGTCCATATCGCCGCGATGTCCTCTGCGAACGCCGGTGGGCGTCGCACGATCATCGCAACCGACCCGATGTCACTCATCGATGTGGCCCAGGTGATCCGTGAACGACTTCCCCAGGCAAGCCACAAGGTGCCCGCACGGGCGATGCCCACGTGGTTCACTTGGCTCGCCAGCGCATTCCAGCCTCAGCTGCGCGACAACCGATGGCTGATCGGCCAGAATCAGCGCTTCGACCGCACGCCCGCCGAGACCCTCCTCGGGCGCCCGCTCCACCCGATCCCTGAGGCGATTCAGGAGACGGGACGTAGTCTGGCCGAGCGACACCTCATCTGACCCCGGCGACGCGGTCCTCGCACGCCGGCTCGGCTGCACCGAGATCCTCGGCCCGGGCTACCTGGGCCACAACGACCACACCCACGTCGCCGGTGGCTGCGGCCGCTTCTGTCCGCGCCCAGCTGCGACATCTGACACACGTCACGTGCCACACCTCGCGTGCGGGGTTCTGCCGGCCCGCCGACGGGCCGGCAGAACCCCGCACGCCCTTGTGTGTGGTCAGTGGCCGCGCTTGATCCACTTGTCGAGCTGCGGGGCTTCCGCGCCGATGGTGGTGGGGTCGCCGTGGCCGGTGCGGACCTTGGCGTCGCCCGGGAGCGTGAGCAGCCGGTCCCGGATCGAGTCGATGATGGTGGGGAACGACGAGAAGGGCCGGCCGGTGGCGCCGGGGCCGCCCTGGAAGAGGGTGTCGCCGGTGAAGACGGTGCCCAGCCCGGGGGCGTACAGGCAGACCGCGCCAGGGGCGTGGCCCGGGGTGTGCAGGACCGTGAGCGTGGTGCCCGCCACGGTGATCTCCTGGCCGTCGGTGAGGGCGCCGTCGGGTGTGCGGTTCGGGTGGGTCTGCTGCCAGAGCGGGAGGTCGTCAGGGTGCAGCAGGATCGGGGCGCCGGTGGCGTCCGCGAGGGCCGGGGCGGCGTCGATGTGGTCGTTGTGCGCGTGGGTGCAGACGATGGCGCGCAGCGTACGGCCGCCGAGCGCGGTCTTGATGGCGGCGGCGTCGTGGGCGGCGTCGATGACGATCGCCTCGGTGTCGTCGCCGACGATGAAGACGTTGTTGTCGACGTCCCACTCGCCGCCGTCGAGGGCGAAGGTGCCGGAGGTGACCAGGTGGTCGATGCGAGCGGTCATCAGAAGACCACCACCGAGCGGAGGACGCCACCGTCGTGCATGCGGGCGAAGGCCTGCTCGATGTCGCCGAGTCCTATGGTCTCGGTGACGAAGGCGGCGAGGTCGAGGCGGCCTTGCTGGTGGAGGTCGACGAGCATCGGGAAGTCGCGGGAGGGCAGACAGTCGCCGTACCAGGAGGACTTGAGGGAGCCGCCGCGGCCGAAGACGTCCAGGAGCGGCAGTTCGAGCTTCATGTCGGGTGTGGGGACGCCGACGAGGACGACGGTTCCGGCGAGGTCGCGGGCGTAGAAGGCCTGCTCGTAGGTTTCCGGGCGGCCTACGGCCTCAATGACGACGTCGGCGCCGTTGCCGTCGGTGAGGGCGCGGATCGCCTCGACGGGGTCGCTGGTGTGGGAGTTGACGGTGTGGGTGGCGCCCATCACCTTCGCCGTCTCCAGCTTGCGGTCGTCGATGTCGATCGCGATGACCTTCGCCGCGCCGGCCAGCCGGGCTCCGGCGACGGCTGCGTCGCCGACGCCGCCGCAGCCGATGACGGCGACCGAGTCGCCTCGGCCGACCTGGCCGGTGTTGATGGCGGCGCCGATGCCCGCCATGACGCCGCAGCCGAGAAGTCCGGCGACCTCCGGGGCGACCTCGGGGTCGACCTTGGTGCACTGGCCTGACGCGACGAGGGTCTTCTCGGCGAACGCGCCGATACCTAGGGCGGGCGACAGTTCGGTGCCGTCGAGCAGCGTCATCTTCTGCTTCGCGTTGTGGGTGTTGAAGCAGTACCAGGAGCGGCCGCGCAGACACGCACGGCACTGGCCGCACACAGCACGCCAGTTGAGGATGACGAAGTCGCCGGGGGCCACGTCCGTGACGCCCTCGCCGACCGACTCCACGACACCCGCGGCCTCGTGACCGAGGAGGAAGGGGAACTCGTCGTTGATGCCGCCCTGCTTGTAGTGCAGGTCGGTGTGGCAGACGCCGCACGCCTGGATCTTCACAACGGCCTCGCCGGGGCCCGGGTCCGGGATCACGATCGTCTCGACCCTGACCGGCTCGTTCTTCGCCGGCGCGACGACCGCCTGGACTTGCTGCGACATGCCGTTTCCCTGCTTTCCGTGGTGAGAGGTCGACCGCCAGCACAGGCGGAACCGCCCGTGCGACGCTCATGCCTCCAGCCTGCCTACCGAATCGGGGATCAGCAGCCAACCAATGTGGCATTTCACCTACCCGTTCGGGTAGGTCATCGGAGCACTCCGGGATTACCGTCTACATATGTCCGACTCACTGCCCCCTCTCTCCGGTGCCAGCCTCGCATCCCGTATGGCCTCCGTGGCGACGGCGGGCCTCCGCGACGTGGCCGATCGTCTGCACACGGCCTTGCGGGAGGTGTGGCCGCACGATGCGCTGGTGATCTTCACCAAGGAGTGCACCGGCCGGCCCAGGAAGAAGGCTGGCGACCCGCTGATCACCGAGGGGGTGACGATCTCCGAGCTGGACTCGCTGCGGGACTGGGCCTCCCCGGGGCTGTGGACCGGTGAGGCGGTACTCGGTGGCCGAACGAGATCGGTCGCCCTGCTCGGAGCCGACACCGGAGCGCTCCTCGTCCTCTGCGGGCCCCGTGACCCGGTGGTCACCGACGGCCCGGCCCACGCGCGTGCCCTGTGGGACGTGGCGTCCGTCTGTATCGCCCACCTCGTGGCCGAGGCGCGTCCCGACTACCTGCGCGAGTCCCGTGCCGCCACCCATGAGCGGCTGGAGGTGACCGCCGAGCTCACCGACCGTCACAGCACCGACCTCGAGTCCCTGCTAGCCGTGCTGCGCGGCAGGAACCTCGACGACTCGACCGCCCGGGCGCAGGCCATTGATCTCGCCGCCGACGCGCTCATCCGCACCCGGACCGGCGGCGACCTCGTGGTTTCCATCGCCGAGGAGCCGGTCGTCACGGCCTTCGAACGTCTTCGGAGCGACCTGAGCCCGCTGAGCCGCTACCAGTCACTGCAGATCCAGTTCGTCGAGCCGCCCTCCGACGGCCGCGCCCTGCCGGGCGAGGTGGCACACGCGGCGAGGGCCATCGTGCGCAGCACCGTACTGCTGATGCGAGAGCAGGAGGACGTGACCAGGGTCAGGGTCCAGTGGAACTGTGACGGGACGAACCTGCTCGTGTCGGTGCGCGACGACGGCCCCGGCCGCCTGAACCGCGAGCTTCCGGCGGTGCGCCAGCTTGTCGCCCGTGCCGCCTCGCTCGGCGGCCTGCTCGACCTGGAGGCGATCGACAACTGGGGGTCCCGGGTGGAGGTGCGGTTGCCGCTGGACGCCTCGCAGCCCCTCGAACAGCTTCCCGGCTCCTGGGGTCTGCGGCCACGGGAGATCGAGGTGCTGCGACTGCTCACGGCCGGTCAGCGCAACCGTCAGATCGCGGCTCGGATGGGCATCAGCGAGAACACCGTCAAGTTCCACACGAGCAGGATCTACCGCAAGCTCGGCGTCACGTCCCGGGCCGCCGCAGCGACTGTGGCAGCCGAGGCCGGTCTCCGGTAGCGCCCGGCGCGGATACCGGGCGGGCGTCCGGGCTGATGCGGGAGGGACTCCCCCCTCTGCCTACCAGCCCCTCTCCTCCACCACGGCCAGCGTCGCCTGGAGGACGTACAGAGCGCCGTTGACGATCCGGTGCTCCCAGGACACCGCGACGAACTCCCTGATCGTCGCACTCGGCCAGAAGTAGGCAGTGGTGGGAGTGCCGATCACCTGGCCGTGCACGTCCTCCTTGCAGGCGGTCATCACGGCCGGACCGGCGCTCGCCATGGGGCCCGCTGCTTGCGCTGGCAGCTGGGGCTGGTCGGCTCGGGCGGCGGCACCCGTGGCCAGGTTCGGGCCGTGGCGCTCGCGGGCGGCGCGGTCGTCGGCGGCGGGGCCGGATTCGGCCGCACCGCCTCATTCGGCCCGATGATCGAGAACTTCAGCGGCCGTCGCTTTGGCAAACTGACCGTCTACCGTGGGCCATCTTCGCCAACGCCGTGCTCGGCGTGGTCACCGGTGTCCTCCCTGCACTGGACCGGCGATCGTGGCGGACCGCCAGTCGGTCCTGGAGTCGCTCACCGACGGTGGACTGAGCGGCAACACCCGGGACTGGCCGAGCGAACAACCGAACGGTGGGGCCTTCCGAGGCCGTAGTGGACGCACAGAGTGTGAAGACCTCGGGCAACGCCGCCGAGACCGGCCAGGGCATCGACGCCAGCAAGAAGATAGAAGGACGTAAGCGCTACCTGATCACCGACACCCTCACGTGGTCCTGACCGTCCTGGTCACCGCTGCCTCCGTGCACGGTTCCGCCGGCGGCAAGCAGGTTCTAACCGAGCTGGCAGCGGCCTATCCGACTGTCACCAAGGTATGGGCCGACGGCGGCTACTTGACCGGCGTCGTCCAGCACGGCGCCAGCCTCGGAAGCGACGTTGAAGTAATGCGACAACCGAAAGCGAAGGCTTCCAGCCGCCGCTCAAGCGGTGGGCGACGAGTGGACCTTCGGCTGGCTGATGCGATACGGCCGCCTCACCCGCTATCACGCATCAACTCGTTGGGCGTTTCTCCACCAAACGTGTACGCGTGGATGCCGCCCAGCGAGTGAGGGCGGCATCCACGCGTACGGGGGCGGCCCGTTGTCAGGCCACGGTCTCAGTGTCGGTTGAGGTAGTGGTTGTAGTAGTAGCCGGCCTTGCCCTCGAAGTGGGCGCCGTGGCCCTCGGCGTAGGTGATGCCGTAGGGGCCGCCCAGGTTCAAGAACTCGCCGCTGCCGTAGCCGCCTTCGACCTTGGCGTGGCCGGCGCCTTCCTTGCCGCCGTTCCAGCCCTCGTCGCCGTGGGCGGCGGCGGGGCTGGCTGCGATGAGGCCTGCAGTGGCGACGACGGCAACGGCGATCGTGACACGACGAAACACGAGTGCTCCTTCTCGGTAACGGATGCGAGCAGTGCCCCTCCAAGGTCGCTCATTTCCCCGGTCAGGCATATGCCATTCGCCTTTCCCTAATGAAAGTGCACTCTGTTGGAGTAGTGACCGTTTGCTGGCCCAGCAGGATGTATTACCTGGAGGTGGCAGAGTCGGGAGTGCGCTCATTTCGGGTTACAGGGCCCGTGAAAATAGTGAGCCCCTTCCAGCCGGGCGCCCTGCACGGAGCTCTTCGTGTGGGGCTTATATCGAAAGCGGATCTTTAGTGTTGGGTGATCTTGATTGTGACGCATGGAGATCTGACGGACGCGCAATGGGTAGTGCTGGCGCCGTTACCGTCGAAGGGCAAGAAGCCCGGGCGGCCGCAGACGTGGGCAGGCGGCCGTTGCTCGCCGGTATACGGTTAAGGGTCCGCACCGGCATCTTGTGGCAAGGTCTCCCTGCCGAGTATGCGCCGTGGGGCCGGGAGCACGACCTTCCCGCCGGTGGCAGCAGCGGGGCGGCACCTGGCATCGCGTTTTCACCGCGCTCCAGGCCCCCGGAGGCACGAGCGCGCCGCCGGGGCAAGGAAAAGGGGCAGCTGTAGAAGGAACCGCCAGGCGGTGTCATCGTCGAGCCGGACGACCACGGGCTCGGCCGCTCGTGCGAAGGCTTGACCACCCAGGCCGCACTTGGCTGTTGAACAAGGCCAGAAGCCCATGGCCATCGTGATCACGACCGGGCAACAGGACGACTCTTCGCAGTTCGAGGCTCTCCTGATCAGAATTCATGCTCCGAGTCTTGGGTCGGGCAGGCCGCGCACCAGACCGGATCGTGTGCGGGACGACCAGCGCCGTCAATGCCGAGCACCTGAGCGAACTGACACCGACCGAGGAACCACCGACTCCCCGCCCAACCGCCTTCCAGAACTACCTCGACCAGCCCGAGATCCCTCGGTCAAAGTCCTAGTACTACAGGGATAGATCTTGGTTCGTGAGTGCGGCAGGATGGCCTGCTGTGAGTGCACGAGCTCGGATTGACGATGAGATGACGGCGGAGGACCTGGCCGTCCTGGACGCCGAGTTCAAGGCGGTGTGCGCCCGGATCGAGTCGCTGTTCTATCGGCCGGAGTCGCGGGCGCTCGCCCGCGGCTACCTGCGGGGACTGCTGGCACCGCTGGAGAAGAAGAACGGCTGGACCATCGCCGAATACACCGGCGCGCCGGAGTCTAACGTGTCCAGAGGTTCTTGAACCTGACCCCGTAGAACGCGGACCGGATGCGCGACCTGCTGGTCGGGTACGCGATGGAGTACTTCGCCGACGAGCGGGCGGTGCTGATCGCGGACCCGACCGGGTTCGCGAAGAAGGGCCGCATGTCCGCTGGGGTGCAGCGGCAATATTCCAGCACGCTCGGACGGATCGATAGTTGCCAGATCGGGACCTTCCTCGCATATGCGACCCCGGATGACCGCTGGCTACTGCTGGACCGGGAGTTGTACCTGCCTGAGCACTCCTGGGCGGCGGACCGGGAGCGGTGCCGCCGCGCCGGCGTCCCCGGCGAGGTTCCGTTCCGCACCCGGCCTCAGCAGGTACAGCTGATGGTCGAGCGGCCGCTGGAGGCGAAGGTGCCGTTCGCCTGGTTCGCCGCGGACGAGGAGTTCGGGCAGAATCCCGCGCTGCGCGCGTTCCTGGAGGACCGCTCGATCTCCTATGTGATGGCGGTGCCGAAGAACGCCGAGACTACCGACGCCGCCGGGCACACGGCCCGGATCGACGCACTGGCCGCCGGTCTGCCCGATCGGGCCTTCGCCCGCCGGCCCTGGGGGATCGGCGCAAAGGGCTTCCGCACCTACGACTGGGCCGTGATCGACACCCCCGATCCCGACCACTGCTTCCTGGTCCGCCGCAGCCTGGACGGACGCGAACTCGCTTACTTCCACTGCTTCAGCCCCCGCCGTGACCCGGTCGGCGAGCTGGTCCGCGCCGTCGGCTCACGCTGGCCCGTCGAGGAGTGCTTCGAGGCCGCCAAGCAGGAAGCCGGACTCGACCAGTACCGGGTCCGCCAGTACGACGCCTGGCACCGGCACATCACCATGTCCATGCCGCCCTGTGCCTGCTCGCGGTGATGCGCCGGACACCTCAAAAGGGGCGCCTCGATCTGTGGACAACCGCCCACCATCGGGTGGCAAACCCACCGCAACCATCTGAAACAACCACATGGATCGGGCGGCCCTCATCGGGCAAGCAGCCGGTCAGCCTGGCCGAGACCCGCGGCCTGTTCAACCTCATAGGCCGGCCCCTCCACGAGATTCGAAACGCTCTGCACCGGTCAACGCTCCGGCTTCGGCACCAACGTGAAGCCCGGCGCCATCACTTCCGCCGCCGGATGCGCCTCCAGATGATCCAGATCTAGTTTCAGCGCTGGTCGGAACGGGTCTTCATGCGGTGGGGAAATCGATGGCGACACCGCCACGGCGGATGACAGGGTGCGGTACATGACGCCGCAGTATCAGATCCGCGCCGACTACGACGCCCGCACCATCGTCGTCTACCAGGCGTACTCGTCCGCGATCGCCGACGCCGCACTGCGGGCGGGGCGCTTCGTCACGCCCTTCTCGTTCCAGCGGATGACGTGGATCAAGCCCTCGTTTCTGTGGCTGATGCACCGCAGCAACTGGGCCCGCAAACCGGGGCAGGAGCGTGTTCTCGCGGTGCGGATGACACGAGACGGCTGGGAACAAGCCCTGTCCCAGGCGGTTCAGACCACCGCAGTCCCGAAGGCAGTGGCTCAAGCTGCCGTGCACGTTCAGTGGGACCCCGAACGCTCGGTGCGTGGAGCGGCTCTCAACCACTACAGCATCCAGGTCGGCATCGGCCGCCACCTGATCCGCACGTTCGCTGAAGACTGGGTCGTCAGCCTCACCGACCTTACTTCGCAGGCCCACAAGGCCGCGGCGCTCGTCCGAAACGGACGCGCCTCCCAGGCTCAGCGACTCCTACCTGCAGAGCGCGTCTACCCGATGAGCCGGAGCCTGGAAGACCACCTTTCACCGATGTAGAACACGGCCAGCCGGAAGAGAAGGATCTATCCCTGTAGTACTAGCGCACTCCGGGCGCCTGCCCTCGGCAACTCCCGTGGTCCCCGACAGAGCCCAGCTAATTCCCGCGCCGTCAGGGCTTCCTGGCCACCGCGCCGTACATGGCGATGTCCCGGCCGTCGACATCGCTCTGCTCCGGACCGGGGCGCCAAGTGTGAACCTGGGTGACTCCCGGGTCCTGCAACTCCAGCCCGTCGAAGAACGAGGTGGCTGTCGCTAGGTTGCGCAGGACGAAGGGCATACCTTGCTGACGGTATTCCTCCGCCACCCGGTTGACCTCCTCCGGTGCGAAGTCCGCGGTGCCGATGGTCATCGCCAGATAGCTGCCGGACGGCAGGGGCTCCAGCAGCCTGCTGATCAGGCGCCGGTCGTCGGGCGGCAGGATGAAGTGCATGATGCCGATCACCGTCAGGCCGACGGGCCGGTTCAGGTCGATCAGCTCCTGGAACTCCTGGCTGCCGAGAATGGCGTCGGGATCGTGCATGTCGGAGTCCACGTACGCGGTGGCGCCCTCGGCTGAACTCTGCAGCAGGGTCCGCGCGTGTGCGAGCACAATGGGGTCGTTGTCCACATAGACCACATGCGACTCCGGCGCTACCTCCTGCACGATCTGGTGCAGGTTGGGAGGGGTCGGCAGCCCCGTACCGATGTCGAGGAACTGGCGGATGCCGCACTCCTCGGCGAGAAATCGGCCGGCGCGGTGCATGAACCGACGGTTCTCCATCATGTGAATTGGCAGGGCGGGCCAGTGGCGGCTCATCGCGTCGCCAGCTTCGGCGTCGACGGGGTAGTGGTCCTTACCGCCCAGGATGTAGTCGTAGACCCGGGCGGAGTGGGCCCGGGAGGTGGTGAGTCCACTCTGCCGGTCTTGTGGGTTGCTCACACGAAGCCTCTTTCGGTCATGAACGGCTAGTTCGACGGTATGAACGCGGTGCCGGGTCCGCAAGCGGGACGGCCGCACGGGACCGGTTCCCTTGCCCGGGCCGTGGCGTGTTCCCGCACAGTCGACTACGGCTTTGAGCGGGCCTGCAGGGCGATGACAGCAATGTCGTCTCGCCGGTTGTGGATGGCCGGCAAGAGCTTGGGGATCAGTGCCGGCAGGGGCACCCCGGCCTGCACCAGTGCTTCGGTCCGTTCGCGCAGCCGCTCAAGACTGTCGCCGATGTCCGTACCGGGAGTCTCCACGAGCCCGTCGGTGTAGAAGACCAGGGTGTCGCCTTCCCTGATGACGGCGTGGAGGTCGGTACGGGGCAGGGAGTCAGCGACGCAGAGGGGCGGGTCCGGGGCCGAGAGGTCGTGGAGATAGCGGGGTGATGTGTCGCGGGGGATCAGCAGGGGTGGGGGGTGGCCCGCGTTGGCCAGAGTGACGTGCCAGATGCGGGGGGCCTGTCGACGGATGACCGCGTGCACCACCGTGATCATCGAGGGTCCGTCGAGGGCCTGGACGATGCGGTCGAGGCGGCTGAGGGTGGTTGCGGGGCTGGCGGTGGGGCCGCTGTCGTAGGCGAGTCCGCGGAGGAGGCTGTTGACGCGCCCCATGGCGGTGGCGGCGTCCAAGTCGTGGCCCGCGATGTCGCCGATGGACAGGGCGAGGGCGTCAGCGCAGAGGCGGACAGCATCGTACCAGTCGCCGCCGATCTCGGCGGCCGAGTCCGCCGGGTGATAGAGCGCCGAGATCGTCAGGCCGTCGACGGTCCGCGGAGGGGTGAGAAAGGACTGCTGCAGGGCGAGCGCCCTGCCACGAATGCTCTGCAGTTCCATGGTACGGCGCAGCGGCCCGCTCATCTGCTGGAAGACGTCGCGCAACAGGGAGAGGTCGGCCTCGTCAGGTGGCGGGTTGCCCTGGCAGGTCACGACGGCCGCCAGCGCGACGGTCCGGCCGTCGACCACGACAGGAAGCAGCGCGACGCCGGTCGCGTGGGCTTCCCGCAACCACCTGACGGAAACCTCCGAAAGCCCGTTCTCTGGAGGCCCGTCGGGTGGGAAGACCAAGAGTCGATCCGCTTGATCTTCGATGGCCCCTCGGGCTGCCGGGCCGAGCGTGAAGTCGGCGTCCAGCGGAGGCAGGGGCGGCAGCCCGGGGGCAAGCCCCACGTGGCCCGGCCAATTCTTGGCCGGTACGCCGGAAGAATGACCACCACTTTCCTCACTGTCTTCTACGTGGAAGATGGCCACGGCATCAGCGAGTTCCGGCACCACCGCCGCCGCCGTTGTCAGAAAGGCTTCCGACAGATCGTGGGCGGCGGGCACCGACGCCATCCGGGCCAGCAGCTTGATCCGCATTTGGGCGCGCCAGTGCTCCTCCGAGTCAGCGGCAGTTCCGAAGAACTCCAACTCCCCGTTTTCGTCGACGACGGGCGCGGCAAAGATTTTGATATGCCGGAAGTGGTCTGTCCCGTCGAGCCTCACCCGGATAGTCGCATCGAGGGGAGACCGCTGCTGTGTGGCCCTGCGCCACGCACGCTGGAACCAGTCGCGGTCCTTGGGATGCAGGGCCTCGATACATGAAGCAGCAGGATTGGGAGTCCATAGTTCTTCGGCGATCCCGCCCCGGGACAACACGGTGACGGCACCTTCCGGCGACGCCACCCATAGAGACTGTGGAACAGCTTTCATAAGCGCCTGGTACCACCTGTGGAGACGCCGATCACTCACAGGCATCCCACCTGTCTCTGGGTGTGCAAGGCTCGGCGGCAAGGCCAGCGGCATGTTCGCTGCCGCTGACTCGGATTGCCTCCAGGCTCTCTCTTCATCAGACAGTGCCTGTGGATCATCGCCACTCATGCTGTAATGATCTCTCTTGTGCGGAGTATCAGCACACCCAGGTGCATCGCGCGGGCCGCCGACTCCCCAGGTCTATCTCCGTCGTAGCAGGGCAAAAATTCTTGGGTTACTGAGCCATGACGTTCTCGGCGGATGCTTCGGTGAGGTCTGTTTCACTACCCGCCTTCCTGCCGCGAGGGCTGGATCGGCACCACCTACGCCGGCTGCTTCCTCGGGGAGGGCCTCCTCGCCTATGCCGGAATAATTGCCGCCGGGCCCGGCCCGACGCCGACTGCATCAATCAGATCGTGGAGCCCTGGCTGAGCCAGGGCTTCGAGACCTTCCCGAGCGGACTAACGAGTTGGTGTGTGACAGCGGGCGAGGCGTCGTGCCAGGCAGGTGACATGATCTGGGCGTGGCGATGATGGTTAATCGGGTGGTGTTCGGCCATCGGCTGTTGGGATCTCTCGGCGGCGTCCCGTCGACCGGGCCAGGGCGGGCAGCAAACACCACCTGATCACCGAAGCCGCAGGCATACCACGCGCCGCCACCTTGACCGGCGGTAACCGCGACGACGTCACCCAGCTCATCTTGCCGCCGCAGGCCGTGCCGCCGGCGCCGGGGCAAGAGCGGCCGGCCCCGGCGCCGCCCGGAGGTGGTGCTGGGTGACCGCGGTTACCACGACAAGCACCTTCGTCTGTGGTCTCGGCATGAAGCCGGTGCTCGCTCGGCGCGGCACCGAGCACGGCTCCGGTATTGGCACCCAGCGCTGGGTAGTAGGGCGCGCCTTTGCTCACCTGCACTGGTTCTACCGCCTGCGTATCCGCTGGGAGATCCGCGACGACATCCACGACACCTTACTCACACTCGGATGTGCACTCAGCTGCTGGCGACGCCTGAAGTCATTCCGTAGAAGTTGTACTGTAACTGCTGGTCAGGGGTAATATGATCTTGCCGTGGCTGGTGTGATCGCGGCATGGCGCCCTCCCGGATAGGCCCGTTAACGGAGCTGAGCCTCCCGCAGCTCCGCAAGTTGACCGCCGCGTTGCGGCGTGAGAGAGCCGATCCCGTCCGCAAGGGCCGGCCGTGGTCGCTTTCCCTGGAGGACCGGGTGCTGTTGGTGGCCATGTACTGTCGCCCCAACCTCATCCTGCGTCAGGTCGCTCCTTCGACATATCCAAGTCGGCAGCCGACCGGATCGTCGGCAATCTCGGGCCTGCTGTCGCCCTTCAGTTCCGACGACGGTTCCGCAAGACCACCGTCCTGATCGTCGACGGCATCTGGTGCCTACCCGGGACCGGGCCGTGGCCACCTCCAGCAAGAACTACCGCCACTCCACGAATCACCAGGTGGTCATCGACGCCGACACCTGCCTGGTCGTCGCCGTCGGCAGGCCGCTGCCCGGTATCCGCAACGGCTGCCAAGCCCGGGAGGACTCCGGCGCGAAGGCCCGCCGTCGGCACCCCCCCCGCGGTGATCGCCGGCGGCGGCTACCGCGGCACCGGCCTGACCATCCCGCACTACCGCCGCTACCAGAACGAGGAACTGGCGGCCTGGAAGGAGGACCACAACGCCTCCCACCGCAAGGTTCGGGCCCGCGACGAGTACACCTTCGCTCACATGAGGACCTGGAAGATCCTCCGTGAATGCCGACTCAAAGGCGACGGTATTCACCACGCCATGCTCGGCATCGCACGCTCCACAACCTCACGCTCGCCGGCTGAACAGGAAACAACGCCGGCCAACCCGCACGCGATAGGTCATGTACGGGACAACTGCAACCTCTTGGAGCGCAGAGCCGACCTCACCAGGGATTAATCGAACTGACCCCGGACTCGTATCCCTTTGCCGCCTTCGAACCCCATTCTGTAACGATTAGTTAAACGCGTAGCGTAGTTGCCGACCCTGCGTAGTCGTCCGGCAGCTGGAGTTCCGCCCAGATGGTCTTACCGCCTGCGGAGTGCCGGGCGCCCCAGCGCTGGGCCAGCTGGGCCACTAGCATCAGCCCACGTCCGCCCTCGTCGAACCCGGTCGCCCGGCGCAGATGGGGGGCGGTGCTGCTGGTGTCGGAAACCTCGACGATGAGCGTGTGGTCCAGGATCAGCCGCAGCCGGATGGGGCCGGACGCGTGCCGGATGGCGTTGGAGATCAGCTCAGTGACCACCAGTTCGGCGGTAAAAAGCGTTTCCTGGAGCTTCCACTGTGTCAACTGCTCGTCAATGCCCTTGCGTGCGATCGCGCAGATGGCTGGGTCGTCGGGGATCTTCCACGTCACGACGTGCGCCGCGTCCAGAATCCGAGTGCGCGCCATCAACAGGGCCACGTCATCGTCCGGCGCTCCGCCCGGCAGCAGTGCCTCGATGACCGCCCCACACCGGGCATCGAGCGAGGCGGCCGCCGGGGGGGGGTCACCGCCTTGTGCAGCAGACGGTAGCCCTCGTCCATGTCCCGGTCGCGGCGCTGCACCAGGCCATCGGTGAACAGCGCCAGCACCGAGCCCTCGGCCAGTGAGAACTCCGCTGATTCGAAGGGCAGCCCGCCGAGGCCCAGTGGCGGCCCCGCGGGCAGCTCCATGGTGGTGACCCTGCCGGTCTCCGGATCGACTAGGACCGGTGGCGGATGTCCGGCCCTGGCTATCGTGCAGCTACCGGTGACCGGGTCGTAGACCGCGTACAGACAGGTCGCACCGATGTCTCCCGCCTCCTCTTTGCCCCCGGTCTCATCGGAGAGACGGAGCACGAGGTCGTCCAGGTGGGTGAGGAGCTCGTCCGGTGGCAGGTCGATGTCCGCGAGAGTGCGTACCGCGGTACGCAGGCGGCCCATGGTCGCCGATGCTTGCACCCCGTGCCCGACCACGTCACCCACGATGAGGCCCACCCGGGCCCCGGACAGCGGGATCACGTCGAACCAGTCGCCGCCCACCCCTGTCCGCCCGGCCGCCGCCAGATAGCGGTGGGCGACCTGCACGGCGCTGCGCTGGGGCAGCGCTCGCGGCAGCAGGCTGCGCTGGAGCGCCAGTGCCGTCTGCTGCTCCTGGGTGAACCGCTGCGCGTTGTCCAGGCACACCGCGCCCCGCGCCACGATCTCCCGCGCCACCAGTACGTCGTCGGGCGCGAACGGATCCGGGCGGCGGTACCGATAGAACTGCGCGACTCCCAGTGTCATCCCGCGAGCCGACAGCGGCACCGAAAGGATGGAGTGCACCCCGAGCTTCCTGGCGTGTCGTGCCCGCACTGGCTCCTGCTCCGCCCAGGAGCGGAAGGCCGGATCGTCCGTGTGTAGCACCACTGACTCTCCCGAGAGCACCGCCCGCACCGGAGAGGACGCGATGGTGTGGCTCCACATCTGCCCGGGCTCCACCAGTGCCTCGGGGGTGTTTTCCCGGACGGAGCGGTGGGAGACCCGGCGCAGGGTCAGCATGCCGTCGTCCAGCGACGGCGCGGCGCTGCTGTGCACGTACGGGGTCGCGAGCAGGTCCACGTGGCCGAAGTCGGCCAGCCGGGGGACGCATACGTCGACCAGCTCCTGAGCGGTGCGGCCGATCTCCAAGGTGCTGCCGATCCACCTGGTGGCGTCGTTGACCAGTCTGAGCCGGGCCTGAGCCCGGTCCTCGCCGGTGATGTCGACGGCGGACAGGGCGACCGCCACCAGCTCGCCCTCGCCGTCCCACACCGGGGCGATACGGGCCAGCCACGCGTGCTCGCGCGACTCGCCGCCGCTTCGGAGCCGGGTACGGACGTCCCTGGGCCTGCCGGTTGCCATCGCCTGGCGCAGTTCCTCCTCCAGTTCGATGCTTTGTGGCTTGCCGCCGATCTCCGACAGTCGCAGACCGCGAGCTTCGTCCTCTGCGAGCCCGATGACCTCCTCCATCGCCCGGTTCGCGCGCCGCAGCCGGACGTTGGTGTCGTAGAGTGCGAGCGCGTTGGGTGCGTAGAGGAACGCGGAACGGGGTAGCTGGTCGTCTTCCGCAGTGCGGTCGGTGCCGACCAGCGGGCTGACGAGCAGCCACCCCGCCGAGCCCCCTTCGTGTTGCTCGAGCCGGTGGGCTAGCAGCCGTACAGTCACCCGTCGGCCGTCGCGGTGCCACAGGCCCACGGTGCCCTTCCAGCGCAGCGGCCACTCGTCGCCGAACGACGCTGGGGCGGGGTCGGCGAGCAGCTCGGCGGCCGGGCGGCCCCGCATCTGCGCCACGGTGTGGCCCAGCAGCAGCTGGGCACCGTCGTTCCAGTGCGTGATCCGTCCGGAGACGTCCAGGAGGGCGCGGGCGGTGGCCCCCTCGTCCGAGACCGAACCCCAGGGGTCATCTCCGCTCCGGGGCGGTTGTCCAACGCCGACGGTGCTCACCTCCCCAGCCTGAGGTCACCAGCGAGGGACTGACAAGCCGAGACCGCCAGACGGGGGCCTGCTCCGGTCGTTAATCGCAACATCTCCATGCCCCGATGAGGTGCGGGAGCGCATGGACCTCTTGCCCCTTCGCAGTTTCACGAAGGGGCAAGAGGTGGTGATGGGATGGAGGGCTACACGGTGTCGCGGACCGTGCCTTCGAAGGGGGCGCCGAGCGGCTGGGCGGCTTCATCCGTCAGTTGGAGGCGGGTGTACTTGACTGGTTCGCTGCCCTGGACGCGGATGGTCGGCATGAGCAGGATGGCGGATACCTCTCCTGCCGGGATCTCGTGCACCAGGGGCCCGTACGTAGCCTCGGAGAGTGGGCCGCTTCTGCCACCCGCTTCCGCCCGGCGCCGGGCGGCTCCGCGTGCCGGACCAGGCGGCTCTCGCTGGCGTTCTGTACGTCCTGCGGACCGGGGGCGGGGGTCGCCGGTCGCAACATCCCGGCCGAGACAGTGGGCTGCTCCGGAGCGGCTACGACTTCGACAGGTACCGCCACCTGCTGTGGAGGTGTGGGATCGAACCACTGATCGCCTGGCGCGGCGGCGCCCACGACTCCGGACTTGGCAAGGTGAGCTGCGAGCACACCTTCGTCGGCCTCCACCAGTGCAAACGACTCCGCACCCGCCAGGAACCCAGAGCAGCCCCCCAACATAAGATGCGCTCGAACTGGCCTCCGGACTCATATGCGGTCCGAACTCGCCAGGAAGCTATGACCGGGCAGCCCAAGTCCCGGGCGGCCGGCCGGCGGTAGAGCTCCAACGGAGGTCGGCTGGGTCCGGGTTGCGTGGTGGCAGAGCTGCACGCGATGGGACAGTTGGCACCGTGGTGGTGAGGGCGACGGAGTCCAGAGTCCGGACGACGATGTCGGACTACGTGCCGTTCAGGACGGCCAGGGGGCTATCGGGTGGCTCGCGTGGATCGGACGGTGCGCGCGGTCCTGGTGGTCGGCGGCCTGGCCCGGGTGGTGGCCTCGGGGCGCCGCTGCAAGGGCGGGACGGCCTTCGTGCAGTGTTGCCAGCGGACGCGGACCGAGGAGACGTCGGCGAGAGCGCGGCGGGCTCCGACGACGAACTGGAACGGGGTGTTCGCCCGATCCCTCTGCTCGGCAAAGCCGGACTCGGTTTCCTGGGGCTGGGTACCCTGCTCGGAAGCCTCTACGCAATACAACGCGTCACTTTCGTGGTTATTCATCTCTCCACCGATACGTCGTATCCTGACTTGGAGAACTTCCTCTCTACGCTGTTGAAGCAGGCCGCAGTCCTCTCGATCGCCTTCGGGCTCTGTCTTCCCCCTCTCTCCGTCGCGGTCGACTACGCCCGATCCTGGGACACCCTGCGCCGACTGCGCCCGCTATGGCGAGAGCTGACAGGCGCAGCGCCGTACGTGGTACTTACGACAGCAGTTCGGAGATGGAGAATTCCTTTCCGGCTAGAGCGCTGCGTCATTGAAATCGAAGACGCCAGCCTCGCCCTTCGTGAGTACGTTTCAATGAACGTGTACGAGAAGGCGCAGGATTTTGTTCGGCGGGAGGGTGCTCCCGACGAGGATGTCGACGCCGCTGCGGAAGCGGCCTGGCTGCGCGCAGCCGTTCAGCGTACTTCAGCACATCAACCGCTGAAGGAAGTGGAGTATCCGCCTCTGGGTGTCACTGACCGGGACAGGGTGAGCGAATTGGCCTGGTTGCTGAAGGTGGCTAAGGCGTACAGATCCGCTACGGTGGTGGAATTCTGTGACTCCGGACAGTCATTCGCGCGGCAGTAAGTAGAAAGGAATAGTAACTAATGGCCGCTAATGCTGCAGCAGAGTCGCTATTGGCGCGACAAATTACAGACTGGCTTGAGCCCAAGAATTGGATCATTGCCGTTACTCTACTAATCGGCTGGCACGCTGCTCAGTGGGTCGGCGTCGCTTGGGGGGTGATCGGCGCACTCTTCGCGGCGGTGATCCCCATGGCTTTCATCAAGCATGGTATCCGAAAAGGGCGTTGGGGTGACCGGCATGTTGGAGCCAAGCGCGCACGCCTGATCGTGATGGCAGTAATCCTGCTTTCTGTTTCCCTCGGTATCACCTTGATGGTCTTCTTCGGGGCGCCGAGCATGATGGTTGCCCTAGTCGTGTCCATGCTGGTGACGCTCGCGATCTTGGCAGCAATCACCTTTGCCTGGAAGATCTCGGTCCATCAGGCCGTTTCGGCAGGCGCCTGCGCCATGCTCGTGCAGACTTACGGGCCGTGGATGGCTTTCCTATTCTTTCTGGTAGCGGTTGTCGGCTGGTCCCGGATTGAACTTCAAGATCACACACGGAACCAGGTCATCGCCGGTACCATCCTGGGTACCGTCGTGGCTGCCGCTGTGTTCAGCCTGGCTAAATGATCAGCGCAAAGACCCTAGGAGTCCCAATTTTCGTTTAACTCGAACTCCGGCCGATCCTCGGTAGATCTTGCGGGGTGGAATATTCGGCTGCCGCGCGATCCGCTCCCCGAGCTGGCCCGGATTTCGGAAACGCTCGGCGAGGCAACCGAGTTGCAATTCTTCGACCACATCCCATGTGTAATACCCGAGGTAACGTGCTTGTATTGAATGACCAGGTAGACGCGGTCGACGACGATATCCACACGTGATGGGGGCAACGCCCGCAATCCTCGGTTGAGCCTTCGGTCGGGGAACTCCGCACGTAATGGTGCAGTCGGGTATCGGAACTCTCCGAATAGCTCGGACAGCATGGTGCCCCCTCTGTCGGGTCCGTACATGGGTCTTGCCGGGTTGGCGAAAGCCGCGGCACGGTAGTGGCTGTGCGCGTTCGGCGGTGCCGGGGTTGCCGTTCCTGCGGACCATGAAGGCCGATTGCCTGCCCGGCCCTCCGGGATGGGCTCAGAAGAACGTCGTCAACTCGACACGCTTGTCCTCCGGGTTGAACCGGAGTCCGATCGTGAAGGTCCGGTACCGGCCGTCTTCCACCTCGACGTCGACCAGCGCCGTGTAGAGCAGGTTCCCGTACCCGTCCAGCCGCAGGTTATACAGGTGCCCCTGTGCCACCAGCTTGCTGACCGCGGCCTCCAACGCGGGCTGATCCAGGTGGAGCAGGCCGGCCTGCTCCACGGAGATCCGGTGCTTGCCGTCCTGGAGGTATCCATACCGGCCCGGGGTCATCCAGATGTCGGGTGATTCCAGGTGTGCGGCGTCAGGGCTGAGCGTGGCGAGCGCCGAGCGGTTGTCCTCGCGGTTCTGGCCGGTGAGGTGGCTGTTGATGCGGTAGCCGAGGAACGGCAGGAACAGTGTGTCGATCACTGCTGTGGGCGTGAAGCCGAGTGCTTCAAGCGGCAGCCCCGCGCCGTTTGGCTCGGCACCAATTTCGCTTACACCTTCCAGGATCATGTCGCCCACGCGAAGGCCAGAGTTCATGAGAGACAGACCGAGGTGCGTTTTCAGGACGCTGCGATCGGTGCAGTCGGCGTACCCGACGTAGGCGGGGTGCTCAGCAGCACTGGAGGTGAGGGCGTTGGCCTGATCCTTGGACAGGTTCGTGACGTATACGCAGTACACCTGAGAGGGGTGGATGACTGTGAACGGCCGGTGATAGACGACGCTCTTATCCATGGCCGCCTGCACCTCGTCGGCGGAGTCGTGGAGGATGTCGCCGCGCAGGATCGAGTTGACCGGGAATCCCTTCCGCGGCCGCGGCAGACCGGCTACCCAAGCCTCCGCCACGTCAATGCCGTAAAAGCCGTTGGAGCTCAGGGAAGCCACCGCAGAGTCGAAGAGGAGGACGATCTCCCTGCGGCGGTGATCCGGAATCAGCGCCTTGGCGAGGCTGCTGTAGGCGATGCCCAGATCGTCGAGGGCACGGGTGAGCCGGAGGTGATCGGCGCGCATCATCCGGTGGAACGCGTCGTCGGTGAGGTTGAAGGTATCCCGCATCGCAGCGAGGAGGAGGCTGTTGTGGGTCGAGACCGAGTGGATGTTGAACGGCCCCGCCAGCAGCTCATCCCACGTCGTCGGGCTGTCGGCGGCCATGCCTGCCTCCTCGTATCGGGGTCGCCGCATGACGGGCGAACCACGAGGTTATTCGCCCGAGTTCGCGCGGCACCTGATTTTGGCGGTTCCTGTACAGCTCGCCATGCCGCGGCCGGATCGTGGCCGGCCAGCGGGCGATGGCCTTGGTCACAGGCTGGATGGGGTACGCCGCCGCAGCGACGACGATCACCACCGCCTAGCGCCCGCCGGCACCTCAGAGCCAGCCGAGCTCCACTATCTCCTCGCCCTCGCGAGCCTTGACCGCGTGGAGGAACGGAGGCCCTACCTTCTCCCGCTACGGTTGGTCGGCCACCTCGGCTTGATAGACGACCCTGTCGCTGACACTGACACCCCGGGTGGGGAAGTCACGGCGATCACTGCGCGCGGGAGAGCAGGCACGACCTGCCGATGCTCCGGCCGGGCCATGCCGGAGCATCGGCAGGTGATAGCGGCCCGCTCAGCGGTTCGTCGGCGGCACGATGCCCCTTCGTTGAGATTTCCCAGCCCGGCTTACACGGCACCGGGCGAAGGGTCCTTAGCTGCCGAGCCGTCGGTGGCTTCCCGGGGCCAGACATGGTTGATCACCCAAGCGGACGCTGCCCAGTCAGCCGGGAACGGCATCAGTTCGTCCGTGACGAGCACGTACGCGGGCAAGAGGTCGGGCATCTCGTACGGAACGCGGACGAGATCCCATTCGCAGCGTACGGTCATGGCCTGTGACCAGCCTTCCTTCGACAGAGTGAGGGTCGCTGACCACATCGGATCGCCGCCGCACTCCTCCGTCGTCACATTGAGCTCGAAGTCGTTGACGCGGGCGTCCGCGTTCGTGGAGTCGTAGCTGTCACCCCCGAGGTCTCCGTCGAGTCCGGGGATCAGGGAGAGGGCGTCGAGGAACTCGGTGAAGGCTTCGTCCGGTTCGTGGTAGGCGGAGTCGTCGGTGCGGAATGCCGCAGCCTGGCCCGTCTCGGAGCGGGCCCGGGTCACCACACCATCGTCGAGGGTGAAGCTGAGAATGTCCCGTACCAAGACCTTTGGAATGATCACGGAATGGCCGCTGGTTGTCCCGTCCTCATTCACCCGCGAGCCGTTGTACTGGGCGTCGGCCAGCAGGAACACCTGGGCGGTGACCAGACCCCTGCGGCTGACCTTCATCTGGTTCATGCCGACGAGGGCGCGGATTCGGCCGAGCTCCACGTCGCGAACCTGATCGAGCTCCCATTCGTTGACCTGCTGGCCCAGGTCTGCGACGTCCCCCAGTACCAGATCCCCGTCGGGCGTCCGGCCGGACTCTAGCGGCAGGCCGACGACACCCTGGAGGAACTTCACGATGGTGTTCCTGATCTCGACGCTCGGCGTCTTCAAGACGAAGAGGGACTCCGACAGTGTGTGCAGCGGCACCATGTGCGGCTTCGAGAGGCCCAAGCTCGTGAATGCCCGGTAGACGTCGGCATCCGAGCCAACGATCACGAACGAGTCGACGTTGTTCTCAGCTGCTCGGAGCACCTGCCGGATCCAAGCGCTGTCGGCAGCACCCGTCTTGACGTCGCTCTTCTTCTTGGCGGGTGGATGGAGCTGAACCTGGTCACGTAGTGCCGCCGCAGCCAGATCGCCGTCGAGTTCGAGGATCCGGACGGACGGAGCAAGGCTGCGAACCAACCCCTCTACGGCTGCCATAACCTCTTCCCTCGAAGAATACGGATTGTCGGAGGCCGGTGCCTCCAACCCAGCCGTCCGCATGGACTTATGCACCCTTTTCGCACTCGCGAGTCCCCCTTCCCACGATGCGGCGGCGTGTTCAGCAAGCTCCCACACCACCGGCTCCGGCACCCAGACTTCGAAATTCTCCTCAGCAGCCCGGTCGCCCCAGTCCTTCAGGAGTTCTAGGTTGAGTCCACCGTTGGGGAAGGAATTCGTGTCGAAGACGATCGCACGGAGACCGTGGCGGACAGATTCGGGAAGCGTCGAATGTACGGAGGAAGCCATACGGGAGACGGTATCCGAGCAGTCTGGCCTCGCCCTGGCCCCCGCCAGGTTGGAGGGTCAGCGGGGCAGGGGCACCCGTGGGCTGTATCCGGAGCTGGTCGCAGACGTCGCTCTGGTGAAACAGGCCCGGACCAACTACGCGGCAGCCCTCCAGATGCTGGCCGGCCTTCCTCAGCTCTTCCTCGGTGTCTGACCCTCTACCAGGGCTGGCCCATGCGGGCACCGGGTCGCCACACTTCTGTACCAGGGCGTCCTGGGCGAGGCAGCGGGATCTCCGAGGTTTCGGGAATGCCCCGTACTCCACGGCCCGAGCCCGCTACCGTCCTGACTGGCATTCTCAGCGAGACGGCAGGAGCGCTGCGTTGGAGAACTTCTTCACCCCCAAGAAGATCTGGCAGGGCGGAGGCCCCTTCCCGCACGTTCTGGTGCTGCTGAGCGAGTATCCGGAGTTCCGTGAGTACGCCCGCGCCCACCACGAACTGCTCTCCGAGTACGGCGACATGCTCGGCGTGATCCCCCAGGAGTGGCTGCACTCCACTGTCCAGGGCATCCATCACGCGATCGACGACGGCCAACTGCACCAGCTCCGCGGCACCCTCCGCGACGAGCTGGCCGGCATGGAGCCGTTCCGGGTCCAGCTCGGCCCGGTGTGGCCCGGCGTCACCGCGGTCACGGTCGCCGTCTACCCGGAGGACGGCATGGCCGAGCTCAACAGCCGCGTCCGCACGGCGATGGAGAAGGTCCCAGGGATCACCCTTAGAGCCCCTGAGCTGCGGTTTTGGGCACATGCGTCGCTCGCGTATGCGCGTCAGGACTTCGCCGACCGAAAGCTCAACCGGGCGCTGCGCGCGCTGCGGCCCCCGCGGGTGGACATCACGATCGACCGCGTCCACCTCGTTAACCAATACCAGCGCCCCGACCTGGGCTATTACAGGTGGGACGTGGTCGAAGAGGTCCAATTCGGCTAAGAGGCAGGGGCGTTGCCGGTCTCCGGGCGGGCGCGTGTGGCGGATCGGGCGGCGACGGCGGCTGCGTACGTCATCCAGTCCCCGCCGCTCGCGCGCTGCCAGGTGACGGCGACGCTGACGTTCACGCCGAGCATCCTGGCCAGGACTGCCGCGGGCAACTGCTGGGCGAGCGCGAACAGCGCGGTGCTTCGGCCCTGGCGCGGCTTGACGCCGGCCGCGCGAAGCCGTCGGAGCAGCTGCGAGACGTGGATGGGCTGGCCCGCCGCGCGGCCCGGGAAGAGCCAGTCGCCTTCGTGCCGGATCAGGGTGTCAGTGCCCCGTGATGCGACAAGGTCCAGCATGAGACGGTCCAGTGGCGCCGGCATCTGGATGGGCTCGGCGCCGAGGCTGAGCAGGACGTGCTCGCCGTCCCGCGTGACGCGGTCGGTGGTCAGGCGGTGGATGCTGCTGGCCGTCTGGGCGTACAGCAGCACGAGCAGCCCGGCGACGCGGTCCGCCGTGGCGACGCTGTCCTCGTTCAGCAGCCGCCGCGCGACGGCCCACCGGTCGTCCTGGTCGTGCGGACCGGCCGGACCGGTCCAGCGGATCGCCGGGGCCTTGATGCCGGCCGGCGCGTATCTCCGGCGTACGGCCCACCGGACGAAGGCGGAACACCGCTTCGGGTGCGCGGGCTTAGTGTTGAGGTAACTCTCCACGTCCGACTGCGCGCATCCGCTCAGCGTCTTGTCACGGCCCTCCAGCCAGCGCAGGAAGCCGTCGGCTCCCGCCAGATGGGCCCGGACGTTCTGGATCTGCTGAACGCTGGCGGGCTTGTCCTTCAACCGCCCGCGTAGCCGTCGCATCAGGTGCCAGAGGATGAAGCCGCGCAGAGCCCGCGGGTGCTCGCCGGGGGCGTATCCGTCGAGAGTCTCCTTCACCTCACGCTCGAGCCGCATCAACCCTTCGTCGCGGAACTCCAGGGCACCGACGGAGATCAGCATGGACCGGAAGTGATCGAGCGTCTTGCTCGGCGGCATCGCGTCGAGGGCGTCGTGGGTGATCGTGGACTGCTCGCGTACAAGTGAGGTGATGGTGGACTGGACGTTCGTCTTCGCCAACCAGGTGATCGCGTAGATCGGGCGGTCGACCTGGACCAGGCGCTCACGAAGCCGGTCGAGTTCGGGCGCGATGGTGCCGTCGTCGGCCGTGAAGACCTTGCGCAGGCGGGCGTCGAGACTGCACCGGGTACAGGGCGCGGTCGTCAGCTGCCACGTCGTGCTGCAGATGCGGCACCGTTTCCAGAAGTCCGGGTCGGGGTTGACGCAGCGGGCGCACAACGGCTCCTTGAGCGTTCCGCCGCGGACGAGGCCGCCGTCACCGCACCCGGAGCAGACGATCCAGTGCCCCTTGCACAGGTCACAGAGCGGCTTTCCGGTGGCCCGCGAGATGGTTCCCCGGCCGGTGCGTCCGCAGATGGAACACTCGCGCTCGGGCCGCGGGCGGCACTGCAAGCAGACCGGGCCGGCATCGGTTCGTCCGTAGACGCGGCGTCGGTTGCCGCACCCGACGCAGACCTCCCGGTTCCTCGGGTCACTGGCCCAGCAGGGCTGACAGAAGGCGTCGCCGTTCTCGTCACGATGGTTGATCGGCTTCTGCTTGCCGCAGCGGGAGCAGAGCGAGGCCCTCGCCTTCGCGGCGCATGAGGCGCATACCCGCACCGCTCCAAGCGGCGACTCCAGCGGCTTGGCGCGACCGCAGCCAGGACACGGCGGTGCGACCACCGACGTGGCGCCTGCCGCGCGCAGCTCCTCGATGAACCGCAGGACGCCCGGAATCGGGGCCGAGGCACCTTCCCCGGAAAGGAGTTCCGGACGCTCAACGACAGCGGCGGCGATTTGACGGCGCCCGGCCGGACGCTGATGCGCACGCTCCAGGGCCCCGATGACTGCCTCGGCAGTCACCGCCGAGTCGATCCCGATCACCACTTCGGCCAGCAGCGCCGTTATGTCGTCCTCGACGAAGCACGCCCGGCAGAACGGCCGACCGTTCCGATCCCGGCCGTACACGCTCCGGTTTTGCCCGCACTCCGTGCAGGCCGCGAGAGTCGGAGTCGACACACAAGTCGAACACCCCCACATGCGACCCGCGAAGTTGAGACCCCGCAGTACTCGCCCGCACACGCCGCAGACCGGGGCGGCGAGTTGTTCGGCACCGGCCCGCCTCAGGGCGAGCAGCAGCTTACCGACCATGATCGGCGCGGGCGGCCTCCCGGTGCTCAGCACGTCGGGGGCCTCGGTCAGCTCGGCGGCGAGCCGACGCTGGCGAGCGCGTTGTTGGACGACGTCCGCCGTCACCAAGCGGACGACGCGACGGTCGAGCGAGGTCTCCACCCGACACAGCACATCCACGAGTTCGTCGAGTGGCTCCCGCTCCGGTTCCGCGATCCGATCGTGCGTGGCGGCCGTCGTCACTGATCTCCTCTGATGATCCTGGCCCGCTTGGGCCGCAGACTCCCCAGGCCCTCCGACGTCGGCGCGGCCGAACTCCCGCCCGCTGCAGCCTTCTTCGGACGAGCGCCAGCTCCCGCTACGCTGATGGGCTCGATGAGGTCGTCCATGCGGCAGTCCAAAATGTCCATCAGAGCCATGAGGATCTTGAGGCTCAGACGCTCGGGCCGCTCCACGACCAGGCGGTAGACCTGGCTCGAGGAGAGCTTGATCTCGCGCTCCTCCAAGGGCTCCGTGAGGTCGGTGGTGGAGAACATCCCGCGGTCGGCCATGACCTTGCGCAGGTGCCACTGGTAGTCGAGCTTGGCGGTCATCGCGATATACCTCTTCTCGTCACAGCCCGGCGAAGGCCGGAGCCAGGGCGTTCTGCAGAGAAGTGTTCATGAAGTCGCTGCTGACGTGCGTGTAGATAGCCAGGGAGCTGTCGCACTCGTGGCCGACTTGCTGCTGGATGAACATCCGGTCCACCCCGTCCTCGGTCTGGTGTGTGACGTACGAATGCCTCAGCGAGTGGGGGCAGAGTTCCTTCGGTAGCCCCAGAGTGTCGCGATACTCCACGAACCGGTCGTTGATCGAGCCGGGTCTCAGCCGGCCGCCGCGTTCGGTGATCCACAACGCAGGCTGGTCCGGGAAGCCGAAGCGAGGCCGGACGTTCTCGACGTAGTCCTCGACCGACTCGACGGCCCAGTCCATCACGGACAACACATTCCGGCGGCGCGGTGGCTGACCCTTCTTGGCTTTGCCGTAACGGACGTTGAGCGTCCCGTACCGGCCGAACTGCGGCGTCTTCGGGTTCCTGCCGAAGTCGACCAGGTCCAGCTTCGATGTCTCGGTCCGCCTCAACCCCCATCCGTAGATGACCTTGAACAAGGTGGCGTCCCGGTAGGCGGCGAGCGTGCCCTTGCGGCCGCTGCGGATCGCCCGCTCCACCTGGTCGTCCGCGTAGTCGAGGAAGAGTTGGAGTTCCTCGCGTGTGAACGGTCGGGCTTCGGGGTCGCCCTCGTAGTCCTGGAGGTGCGGGATGGTGTTCCACTCGTGGGCGATCGCCACGGGGTACGTCCCGAATTGCTCTTCGCAGGCCCGTGCCCAGTCGTACCGGGGATCGATGAGGTACTCGGAGAACAGCCGTACTGTGCCCTGGTAGCCGCGTACCGTCGAAGGCGCGAGGCCCTTCTCCGAGGTCAAGTTGGCAGACCACTCGTCCATGTGGGCGGGCGTCCAGTGCCACGGATACTCGTTCGTGTGAGTGTGGAAGGCGCGAACCAGCTTCTCGCGCGGCTCGTATGTGCCCTTCTTGAGGTTGCGGGCCTGCTGTTGCGACCTCCAACCGCTCAGCATCGCTTCCCACACCGTGTCCTCGGGCCGGAAGCGTAGCGCCCCCGAGACTAGCTCCAGGTTGGCCGATCCGGCCAACCCTGTAGTCGGTCGTCGCATCAT

Protein sequences of DBSCAN-SWA_2

>NZ_CP047147|6257097:6386481|6262810_6263233_-|WP_003951810.1|tail|DBSCAN-SWA
MPRQDPGSTIWFTLTIDGESLGYFNGCDGLSSQVEVEHRQEGGSNGFVWTLPTRVTFSTIRLTRPLTPDTTKVAKWISSVQTGIKRPTAQIAALRADGSEVARWGLIDVLPVSWQGPSLDPASPAVATEVLEIAHHGFTD
>NZ_CP047147|6257097:6386481|6295728_6296553_+|WP_159313422.1|DBSCAN-SWA
MTTAHAVHAAHVRLFRSLHTPSAPLALANAWDAASARVVEAAGAPAVATTSAGVAWALGSVDGNSLDRDRALAALAQVTAAVTVPVTADLEDGYGAGPAEVGATVTRALASGVAGINLEDGTRTPADFAARLTAARTAADKAGTDLFLNARIDTYLLGLGAPEHRLTETLTRAHHYVAAGADGIFVPGVTDPATISALAAEIPVPLNVMAGPGAPSVAELGRLGVARVSLGSGVAQTAYGVAGRAARELLAGGTYDALADAVPYPEMQGLLAAR
>NZ_CP047147|6257097:6386481|6367839_6368403_+|WP_159313464.1|DBSCAN-SWA
MTPQYQIRADYDARTIVVYQAYSSAIADAALRAGRFVTPFSFQRMTWIKPSFLWLMHRSNWARKPGQERVLAVRMTRDGWEQALSQAVQTTAVPKAVAQAAVHVQWDPERSVRGAALNHYSIQVGIGRHLIRTFAEDWVVSLTDLTSQAHKAAALVRNGRASQAQRLLPAERVYPMSRSLEDHLSPM
>NZ_CP047147|6257097:6386481|6288571_6290332_+|WP_159313419.1|DBSCAN-SWA
MSRPAPAPRLPVADAATVRRAVRQLVREDSRAVWGTLVLTCLAALAAAAGPWLLGRIVDRVQAGGLAASGIDLLAAAVLGCAAAQLLLTRWARGVSHRFGERALARLREEVVERALALPGRVADKAGTGDLVTRATLDVATVAATLRSAGPDIFVAVVQAVFLFGAIFLLSPLLGLCSLVGLPLIAGVSRWYLARSREAYLAEGAAAGEVSEILNSTALGARTVEAYGLQERRGQVLDEAVDTTYRAGERTLALRSVLFPVTEFAHTLPLALILLAGGFGYLEGALSLGAVVAGGLYMWQLVDPLDQLLVWVEQLQRSGASFARIKGVGLVAHPQDTPVAAPDGDLVEVTGVGYSYLPGQEVLHDVTLSVRPGERLAVVGRSGAGKSTLGKLLAGVDTPDSGSVLVGGVPVAELAAAGELGSRVVLLTQEHHVFLGTLRENMTMAAPGADDAAVLAALALVEAEWVAGLPDGLDTRLGPGGLVLEAAQAQQLTLARVQLADPHTLILDEATSLLDPRTARQAERAMAAVRADRTVIAIAHRLQTAHDADRVAVMEAGRVVELGTHEELVAAGGVYAGLWRSWNGEG
>NZ_CP047147|6257097:6386481|6345025_6345943_-|WP_159313448.1|DBSCAN-SWA
MIDPRLRVLQLVAEHGTVTGAAHALHFTPSAVSYQLRQLAADVGVELVVQQGRGIRLTQAAHILLAHTERLREQWELAQAELATADPARPGRLTLCGFSTAASRLLPPAAATLRRSHPGLTVRIVEAEPDRCFDLLLSEEADLALLVVTADSPPMTDRRFDQHALLDDPLDLVVAEDHPLTRRKQVTLADAATEPWIVGNPGTTYHQLVLAACLSAGFTPEIAHHADEWDTGTALVAHGFGVILVPRLARLRENEPVVRIPLRGEPAPARRITAVTRLGARGAPRLREAIETITDVATQTLPDPI
>NZ_CP047147|6257097:6386481|6346073_6347315_+|WP_159313449.1|DBSCAN-SWA
MPVRPRPRRSLPRTYPTDRHTVRTAALLVAVLTLGAYLPSPLYPDYQRLFGYGDLGTTLLFATFSLVSGPALLLCGPAADTVGPRPVLRLSLLLAAAGSGCFLLADDIVWLFAGRVAQALALGASTGAAQALITRHLGPATRLGGPLLAGLAFAAGTAAGPALGGVLAQYAPGPHLTPYLVHLVLLAWVAVHLHRATPKPTAPRGALRRWRPSRPHIPRAARWSFLIAGANGFLAWAVVGIYLALLPSLLARTPHGGGPALSGGVLAMVLLWSILAQLAGARGSVRGVQQTGVIALIASVLLLAATQAASLPATLGSALLAGAGHGLAYSGATRAVDVRTPPEHRAGVGSALYLLFYLGSGVPAVATGLMATWMSLPTAVTLLSWAAAAFGAVALTATSLNAGATGRPQQGTP
>NZ_CP047147|6257097:6386481|6341756_6342107_-|WP_121842937.1|DBSCAN-SWA
MALIRIDGDDLVVVIEGFDKLWAFKGSLTIPLANVRGVTADPGIATDPKGIRAPGSHVPGLIIAGTFHQDGEKVFWDVRDASKAVVIELADERYARLVLQVEDPRAAVALIEKALA
>NZ_CP047147|6257097:6386481|6281827_6282892_+|WP_030305556.1|DBSCAN-SWA
MSPTSPPPAPTPATEAPGARRRPRFFRAPLRAGALGLALALGLTACGTATEDKAGDKPKTRVFKADNGEIEIPADPKRVVATGYAVPALIEADAALVGISTWKRGLDLMTDKHLARYEKVPKVAGETAAETNYEAIAKARPDLIVIGVPTPVLADIDVKRLESVAPVVAIGPTQPDAWRTLSRRQSDAAGRLDHFEEAKEAYEKRAGELRKKYAKVLDGRRFGHVGAYSEAGKGSFQREFSRSWGTNIAEDIGVTYYGEVKKKTGGSGDVSENPSIEQLPESLGDADVVTYTVQPDGEPAAAVQYVLDSPLWKELPAVRDGLTVPLRYTEAATYPSALRTLDALDKALQPLLDR
>NZ_CP047147|6257097:6386481|6385004_6385358_-|WP_159313473.1|DBSCAN-SWA
MTAKLDYQWHLRKVMADRGMFSTTDLTEPLEEREIKLSSSQVYRLVVERPERLSLKILMALMDILDCRMDDLIEPISVAGAGARPKKAAAGGSSAAPTSEGLGSLRPKRARIIRGDQ
>NZ_CP047147|6257097:6386481|6260135_6262040_-|WP_008411668.1|DBSCAN-SWA
MVRTAFSSVIQVSIGGAELPKDIAPLLVEGWVDQGAGVPAAFRLTFRDPYRIVLGELGVKFGTEVVLTPVADGEGLGDPLLTGEVTGLEADYDGTGSFAVVRGYDFGHRLMRRRRVSAYRNQTASDIARRLAAKAGVPIGRIQSTPALYEFISQPNISDWDFLSRLADENESVMSLDAKGKFQFVKPKASSGAPSPGTDGDKSPFVLQGGHDILRLRAAVTAADQVNKVETRGWNVTTKKKITEVKTLTTDPGISIGVTPGEIARSFKSATLVETASPYDKQSEVQHAAEALATDVTSSFAELEVAARGNPELRPGVPVALSDVGEPFEGKYTVTSVRHVFGDGRHYESWVTVSGRQWRSLYGLASGGSEAGGGASRLPSVANAVVTDVQDPLRQGRVKLTFPWLNDAYVSDWTRCVQLGGKSGGGIFPMDVGDEVLVAFDRGALDHPFVIGGLYNGVDLPTRVPDVPLHDGLRKQATRHTLSDRQGNRVDLLSQRSGGKQGVRVASGDGRLTVNLDRTNTEITVDSDGDVTIKGGKSVSVEAGTDLTLSARRKLTLKSGGIINMQSRGATNLRTLAGGFNVNATGVLNLQASGTALLNAIGTVQINSVASVGMRAINIPLMGVVTINGKPVPL
>NZ_CP047147|6257097:6386481|6296570_6298511_-|WP_159313423.1|DBSCAN-SWA
MTSPVTQEQPPGRPAGAPQDTVPEEAGVREEEFLYRDASRLQAGSLLTTRTMARRLPALVLRSLRLAWGVDRAATVGLLVCQIATGVLAALGLLAVTGTITALVSSGDITERLWEAAPQLAVIAGATGLRALLGIAVVWLTGRLRPVLARAAELTMVEAALGAELAANNKPGYNDAFDIADRGAQVTPDLVEEAQDVLAAAATLTAGAAVLAVLHPLLLPLLLLACLPQAAAYIRSARVMYLAKVATSGRRRMLSKLRWHMAYQESSEEMRACLAGPFLIGRYRKLADSVNTAEREAANTGARMGLAGALAGGVASAAVWAALLWLLSSGRMSLAAGGGAVFALQTATGSVRGMINGGARLVRTGWYVQDWQNFLDNAHGQAMADSRGSRLLSAVPERFEVRNVTYRYDGAPKDSLSGVSLHVRRGEIVALVGENGSGKSTLSRLLCGLLLPTEGEVAWGHTSTAQLDPWAAWGHVALVPQKFTYLPLTMRDNITFGQGDTGDAALLAACEASGASEMLPHLRSGLNTLLTSEWFGGQQLSGGQWQRLVLTRAFHRQAALLVMDEPTAALDARAEHRIFSGLRELAKDRAVLLITHRLTNVAVADRIVVLDEGRIVQEGTYADLTRTPGLFRSLWELQRRMSGDPA
>NZ_CP047147|6257097:6386481|6311452_6312085_+|WP_003951846.1|DBSCAN-SWA
MRFIKKRHSCVRLEKESGTLVIDPGGFTEPDAALGADALLVTHEHPDHFDEGRLRAALEANPAAQLWTLASVAGPMAAAFPGRVHTVGHGDTFTAAGFDVEVHGELHAVIHPDIPRVTNVGYLVDGEVFHPGDALTVPDRPVETLLLPVMAPWNKLSEVVDYVREVRPTRAYDIHDALLTDLALPVYERQIGALAGTDHHHLGPGTFTEV
>NZ_CP047147|6257097:6386481|6380117_6381590_-|WP_159313470.1|DBSCAN-SWA
MASSVHSTLPESVRHGLRAIVFDTNSFPNGGLNLELLKDWGDRAAEENFEVWVPEPVVWELAEHAAASWEGGLASAKRVHKSMRTAGLEAPASDNPYSSREEVMAAVEGLVRSLAPSVRILELDGDLAAAALRDQVQLHPPAKKKSDVKTGAADSAWIRQVLRAAENNVDSFVIVGSDADVYRAFTSLGLSKPHMVPLHTLSESLFVLKTPSVEIRNTIVKFLQGVVGLPLESGRTPDGDLVLGDVADLGQQVNEWELDQVRDVELGRIRALVGMNQMKVSRRGLVTAQVFLLADAQYNGSRVNEDGTTSGHSVIIPKVLVRDILSFTLDDGVVTRARSETGQAAAFRTDDSAYHEPDEAFTEFLDALSLIPGLDGDLGGDSYDSTNADARVNDFELNVTTEECGGDPMWSATLTLSKEGWSQAMTVRCEWDLVRVPYEMPDLLPAYVLVTDELMPFPADWAASAWVINHVWPREATDGSAAKDPSPGAV
>NZ_CP047147|6257097:6386481|6302677_6303727_-|WP_159313426.1|DBSCAN-SWA
MSRSAHRIDVHQHIVPAFYREELAEAGITDAGGRALPAWSPESALRLMDLLGTATSIVSVSTPGTSFLTEPADAADLARRLNDHSAALAGDHAGRFGFFATLPMPGTDASAAEAVRALDDLRADGVTLLASHRGTYLGADGLDALWRTLDDRGAVVFVHPAELPAPPVDGIPAFAADFLLDTTRAAYLLVRNGIPRRYPGIRFILSHAGGFVPYSSHRMALTIADDTGRSPLDVLDDFRSFYFDTALSSSPAALPSLLAFARPGHVLFGSDWPFAPAPAGQYFASGLDEHLTPETRRAVDRANAEALFPRLATTPPPPALAVPGPVRLRQAARRSAARLVFKLLQPGTG
>NZ_CP047147|6257097:6386481|6329931_6330921_+|WP_159313437.1|protease|DBSCAN-SWA
MTTNHTESADVPADGLLRNRWRARMRARPLTFFFVLANGLSWAAWLPYILSQNGLGVWDYQFPQILGTSQVLGVLPGAYLGPIGAAFAMTALVDGRPGLRAWVRRLWRWRVAGRWYAITLLGVPVGMLVTGLAFSGGQVAAPSAAALSAIVPVLLFQIVTTGLAEEPGWRDFALPRLQSRFSPLRAAFILGPLWGAWHLPLFLTEWGGYPEASWTRPLVFLGFCVAFNVVMSWVFNRTGQSVPLSILMHVGANTFASVMWAEMFPGLDGELALIAMGSGAAVAATAIVIATRGRLGYAPSPADLSSGHGGMVPSACRAKYSQNRPMIES
>NZ_CP047147|6257097:6386481|6342120_6342621_-|WP_159313446.1|DBSCAN-SWA
MGRPRAFDEGEAVRAAVRLFGGRAYDGVSVDDLVGHLGVHRNSLYKTFGSKRGLYLIALRRHLADDVRPLLDALGGAPDAATALRLVTGTDLSLLLLATVERAPVDEEVASEVAAAWAAVDQAIADALGVPVDLAAALTATALGILLRGNPDNVAAALTQHLNTPP
>NZ_CP047147|6257097:6386481|6360808_6361438_-|WP_159313460.1|DBSCAN-SWA
MTARIDHLVTSGTFALDGGEWDVDNNVFIVGDDTEAIVIDAAHDAAAIKTALGGRTLRAIVCTHAHNDHIDAAPALADATGAPILLHPDDLPLWQQTHPNRTPDGALTDGQEITVAGTTLTVLHTPGHAPGAVCLYAPGLGTVFTGDTLFQGGPGATGRPFSSFPTIIDSIRDRLLTLPGDAKVRTGHGDPTTIGAEAPQLDKWIKRGH
>NZ_CP047147|6257097:6386481|6309542_6310625_-|WP_159313430.1|DBSCAN-SWA
MTASTATALTHVRVFDGERLREPGTVVINGPLIGTDPAGARVVDCRGATLLPGLIDAHVHVRDAGTLDRLADHGVTTALDMGGWPPALLDSLRGLPGTTALLRAGAPAAAPGSVQSRMPHFPRSSLLAWPGDAPAFVAERAEQGVDYVKIIAEVPGTPGALSQETLEAVVRAARERGLRTVAHASAVAAFAAARRAGVDAVTHVPLDAELPAAEAELTAAEGRFVVPTLAMMEAVAEALGHLGLDYAHARAGVAALHAAGVPILAGTDANNAPGAPASVPHGPSLHHELALLVDAGLTPLDALRAATVLPARHFGLTDRGAVAPGLRADLVLVDGDPLADITATARVRAVWCGGVERPGL
>NZ_CP047147|6257097:6386481|6354135_6355557_-|WP_159313456.1|DBSCAN-SWA
MREHNELYIDGAWRAPLQGSVLELKDPATGVVTGRVALGGEADVDVAVAAAERAFVSYSQTTVQERITLMERILVEFDRRAEDLAQAVTAELGAPLALARGAHVPTGRVQIATAIEVLKTYVFSEMRGETEIRKEALGVAGLITPWNFPVLQPTGKTISALAAGCTVVLKPAQLTPYSAVILAEIMDAAGVPAGVFNLVNGRGSAIGGSLSSHEGVGIVSFTGSAAAAEQVAVAAAPTVKRVTSELGGKSPHILLPDADLEIAVQTAMTWLMAMTGQLCSAPSRTLVPRERLEEFLSVLVPAVEALKLGDPQAEDTTMGPLISAEQWKTVQGYIRQGLDAGARLVTGGLGKPAGLESGHFVRPTVFADVDNTMAIAREEIFGPVMSVIAYDSLDEAIAIANDTPFGLAAYVTGGDREMVRLVAERVRAGYVLINDAEFDWSAPWGGYKQSGNGREFGPDGMSEYLETKVIRSS
>NZ_CP047147|6257097:6386481|6321506_6322781_-|WP_159313433.1|DBSCAN-SWA
MTTESEDLTSGISAQELASGTAEPSTAHTTPEDAPGTRQTSARPEQDTVSSEAPEREPAARPVDGLVRTAVTTRSVPEIVDLIRLLEQSPSGAEAAEEILRTAAVERPVDDVSDLVALLSQPPQPVDRADEAIHLAAAERPIDDVSDLVALLHRPPHDSHAGEEAVHAAATGLTVEELAQLIDRLETERVAGAETGTTPPSAALPAEPSEEEPTGSPLPDGDSASTAHTLGTATVASTTEAPTMHTPTTRPTPSLADGRRPSSRPRQAPEATTQDRQATPAAALPLWLRWTTVAALLLCGVTHFPFQPTGLPTSAYGLAVGIAVLCLLLAAGTLLRRVLPALIADILLMGSLTAAHLLAPATGPQALTSALEPGGTPAVLPAAVAGVLSLLALTLLLTRGRSREGGGPEPTAGSRNLRTRPDPR
>NZ_CP047147|6257097:6386481|6257657_6259616_-|WP_003951806.1|plate|DBSCAN-SWA
MSLPSPNLDDRRFQQFVDDAKRYIQQRAPEWTDHNVSDPGVTLVETVAHMADQIVYRLNRVPDKNHLAFLDLVGITLFPPSAARTEVTFWLSAPQEETVAVAVGTEVATTRTERDEAVVFATERGLDIVPTALSHLVVQRQGGPVTDRTTELAEGKDLLCFSEAPEPGDCMLIGLTAAAPHCALALELDSRVDGVGVDPRQPPLSWEAWTEDGWQPCEVDRDGTGGLNRPGDIVLHLPEGHVLSRNGGHEAGWVRCRVTEPLTGQPFYTTSPTIRSAEAYTVGGTTRAVHAETVRDEALGESTGLPGQRLRLAHAPVVADSPPVLLQTATHEGWHDWEVVPHFASSRPDDPHITLDGATGEIAFGPSVRESDGTLRQYGAVPPKGAVIRARRYRTGGGRAGNVARHAVQVLRTSIPYVGEVVNREAARGGVDGETVEEAKLRAPITLRAQERAVTLRDYEELARRAAPETARITCLEGEEGEHGAYAVRVLVVPQAVPDPGGRLRFEQLVPGDALLDRITRQLDERRLIGTRLAVGPPFYQGVTVVATVHAFRAVDTDRVRRAAHDALYRHLDPLTGGADGRGWPFGRPVQAGEVFAVLQRVPGVELVDEVVLHPADPLTGKRGDPTDRIDLEAPALVFSYDHRVRVVGDTP
>NZ_CP047147|6257097:6386481|6301015_6302668_+|WP_159313425.1|DBSCAN-SWA
MHTTGSVTHEVTNQAPPLTGHDVADDPVLLEGVRREGAAWHLPELHRFGRYAGSEEAQHRADQANRHEPELRTHDRYGHRVDEVEFHPAYHALMDASVSAGLAGAAWADERTGAHVARAAGFMVATTVEPGHLCPVSMTYAVVPALRHAPDLAKTYEPLLTSRVYDPGLRTPAGKRGLLAGMGMTEKQGGTDVRANTTTATEQGDGTWLLRGHKWFTSAPMNDLFLVLAQAPGGLSCFLVPRVLPDGSRNTFRIQRLKDKLGNRSNASSEPEFDATVAWLVGDEGKGVRTIIEMVTMTRLDCVLGSAAGTRAALVQAAHHARHRSVFGAKLIDQPLMRNVLADLALESEAATTLALRLAGAADRARRDDPGERAFLRLATAVGKYWVCKRQPAAVAEALECLGGNGYDEASGMPRLYREAPLNGIWEGSGNVNALDMLRALAREPESLEAFRAEIEAVSGADRRLDTAWRELQSRLTLTEDAELRARRVIERAALVLQASLLVRHAPTPVADAFCASRLAGDRGLAFGTLGPGTDFYGVLGRIPGEPATS
>NZ_CP047147|6257097:6386481|6286778_6288575_+|WP_159313418.1|DBSCAN-SWA
MARNERRDSSGPGARPGHARRVPYTDPGVPDHRTPLRFLWWLTTSQRRRVLLGSLWGTAWMCLLIAPPYLMSRAIDDGLRGRDPGALLLWTGALLATGAALAVLGILRHRTMTRVRVDAAYRTVQVVTRHVTRLGSALPRQVSAGELTHLQAGDIGRIAQTLTVTGPGVGAAAAYAVTAVLLLGISPLLALVVLLGVPALALTVGPLLGRLHGAEGRYREEQGQLTALAGDLVAGLGVLNGIGGKRVFAARHHARSQALVPLGYRVAALTSWVQALTACLLVLFLAVVTWIGARMAAAGTITVGELVAVYGYVSALLVPVSAFIEGADDLPRGLVSARRVTDILALAPPPATGRPRLDPPKTPAELYDPDSGLTVTPGRVTALVGVRPEETRAVAERLAGHGASAVTWGGTPLAAWDRDALRRHLLLADHDAYLFAGDLRTALSGRADRPGDTVRAALDAAAATDIADGLPDGLDGHLDDQARNVSGGQRQRLRLARALLAEPEVLLLVEPTSALDAHTEATVATRLAAHRRGRTTLVVTTSPLVLAQADEVAHLDDGKVRATGTHGELLATRPAYAALVLRGTARDAALRPLEGDAR
>NZ_CP047147|6257097:6386481|6338651_6339131_-|WP_159313443.1|DBSCAN-SWA
MGALLDLLNSRPLINGEERDALGDPAEGRRWAREHGGDGSLAELTLLREARDVLQNVVRGNSSPAALGPLLEGVHQIPEVTSDGLQWAVRFPPHARLAVETVLAWAGTEERMPGRLRPCANTKCQLFLLDRSRANRARWCSMAVCGNREKVRRHYERTR
>NZ_CP047147|6257097:6386481|6280898_6281687_-|WP_067416786.1|DBSCAN-SWA
MRCQEYGYGLGRPEGIFVLRYQSAGPLEFGAIARQDFLHQLYWSPDGALSALHGAEARFLGPGEAFWAQRAVSHEVRAADRQTVYRICLREVPAALAELRAGPVVVPEETGRLVRGLARSGVTEADALADRARIMAALVPYSFAGDGPPGAPASGRGAGHALRVARALAHDPSDTRELAAWAAQLHISAKTLQRDFQREFGMSYTRWRTLLRLSAARALLGTEPVTRIARRVGYASPSAFVAAFAKEYGRTPARYARDGAGA
>NZ_CP047147|6257097:6386481|6368515_6369325_-|WP_159313465.1|DBSCAN-SWA
MSNPQDRQSGLTTSRAHSARVYDYILGGKDHYPVDAEAGDAMSRHWPALPIHMMENRRFMHRAGRFLAEECGIRQFLDIGTGLPTPPNLHQIVQEVAPESHVVYVDNDPIVLAHARTLLQSSAEGATAYVDSDMHDPDAILGSQEFQELIDLNRPVGLTVIGIMHFILPPDDRRLISRLLEPLPSGSYLAMTIGTADFAPEEVNRVAEEYRQQGMPFVLRNLATATSFFDGLELQDPGVTQVHTWRPGPEQSDVDGRDIAMYGAVARKP
>NZ_CP047147|6257097:6386481|6266510_6266867_+|WP_159313411.1|DBSCAN-SWA
MPSAPGSRPAPAAGFSTAGEAVAVNDGFCQVGRVPPKALSATPAPPARAASWTGGSPDHEGTTGAGAGDASATGPDGTAGAGPAESAPGVSGVPPLRPRSRSRNPTAQPSARVTRDAI
>NZ_CP047147|6257097:6386481|6382554_6385008_-|WP_159313472.1|integrase|DBSCAN-SWA
MTTAATHDRIAEPEREPLDELVDVLCRVETSLDRRVVRLVTADVVQQRARQRRLAAELTEAPDVLSTGRPPAPIMVGKLLLALRRAGAEQLAAPVCGVCGRVLRGLNFAGRMWGCSTCVSTPTLAACTECGQNRSVYGRDRNGRPFCRACFVEDDITALLAEVVIGIDSAVTAEAVIGALERAHQRPAGRRQIAAAVVERPELLSGEGASAPIPGVLRFIEELRAAGATSVVAPPCPGCGRAKPLESPLGAVRVCASCAAKARASLCSRCGKQKPINHRDENGDAFCQPCWASDPRNREVCVGCGNRRRVYGRTDAGPVCLQCRPRPERECSICGRTGRGTISRATGKPLCDLCKGHWIVCSGCGDGGLVRGGTLKEPLCARCVNPDPDFWKRCRICSTTWQLTTAPCTRCSLDARLRKVFTADDGTIAPELDRLRERLVQVDRPIYAITWLAKTNVQSTITSLVREQSTITHDALDAMPPSKTLDHFRSMLISVGALEFRDEGLMRLEREVKETLDGYAPGEHPRALRGFILWHLMRRLRGRLKDKPASVQQIQNVRAHLAGADGFLRWLEGRDKTLSGCAQSDVESYLNTKPAHPKRCSAFVRWAVRRRYAPAGIKAPAIRWTGPAGPHDQDDRWAVARRLLNEDSVATADRVAGLLVLLYAQTASSIHRLTTDRVTRDGEHVLLSLGAEPIQMPAPLDRLMLDLVASRGTDTLIRHEGDWLFPGRAAGQPIHVSQLLRRLRAAGVKPRQGRSTALFALAQQLPAAVLARMLGVNVSVAVTWQRASGGDWMTYAAAVAARSATRARPETGNAPAS
>NZ_CP047147|6257097:6386481|6353152_6354001_-|WP_159313455.1|DBSCAN-SWA
MTTWFITGASRGFGLQIARQALDRGDNVVATARTPEAIRTALPGYEDRLLPAALDVTDEAQARAAASVAVEAFGAIDVLVNNAGRGLLGAVEESTDAAVRSIYDTNVFGLLNVSRAVLPVMRRQRSGRVLNISSLGGFSSSAGFGIYCSTKFAVEGISEAMQQELAPLGIGVILVEPGYFRTDFLDATSLHTEDQVIADYASTAGAVREMVPGLNKAQPGDPVKGAAAVLALADADNPPVRAQLGSDCLDELDRKIGQLRRESAAWRDLALSTDHDDTRNPA
>NZ_CP047147|6257097:6386481|6351702_6351966_+|WP_159313453.1|DBSCAN-SWA
MLVDQYRSRSARVSWRVLAMPRTAWWTPSPSRCRARGRTHISRPRLAPHRINVLFAMLRDGMFYEPSTPTPHLTKDTEAPLCFSGAP
>NZ_CP047147|6257097:6386481|6361437_6362523_-|WP_159313461.1|DBSCAN-SWA
MSQQVQAVVAPAKNEPVRVETIVIPDPGPGEAVVKIQACGVCHTDLHYKQGGINDEFPFLLGHEAAGVVESVGEGVTDVAPGDFVILNWRAVCGQCRACLRGRSWYCFNTHNAKQKMTLLDGTELSPALGIGAFAEKTLVASGQCTKVDPEVAPEVAGLLGCGVMAGIGAAINTGQVGRGDSVAVIGCGGVGDAAVAGARLAGAAKVIAIDIDDRKLETAKVMGATHTVNSHTSDPVEAIRALTDGNGADVVIEAVGRPETYEQAFYARDLAGTVVLVGVPTPDMKLELPLLDVFGRGGSLKSSWYGDCLPSRDFPMLVDLHQQGRLDLAAFVTETIGLGDIEQAFARMHDGGVLRSVVVF
>NZ_CP047147|6257097:6386481|6330941_6332177_+|WP_159313993.1|DBSCAN-SWA
MTDSAAGVAAAVTALSALALLWIVTLLARDDPSLGGLPHGTVAWWVTAVTLVLQSATLVCTRHRATAALASTAALSLVLAVVFPSGLFTVTALPVLVAAFLAGLTEAWRDVRRWAPASGALVAVAYFVNSTTDGNSDGTALSMQAVLQAALVVGLPLLPASLIAAQRDTRAAQQETLAAVTRERDAKISEAIALERAAMARELHDIAAHHLSGISIMASVVARQTTSAPSEARSGALEIRRQSNAILEDLRRLVGLLRDVGPDDEEVKTLITIPGLIEAARLAGARVESDLRIAERRELGAGIGPLGQLAGYRMVQESLTNASRHAPGARCLVTVDDRSPLRLQLTVRNAPPSGAQVRPTPSGTGFGLMGMKERALLIGGDFDAGPTDDGGWETRMSIPRESEHNFPEPPT
>NZ_CP047147|6257097:6386481|6335693_6336560_-|WP_159313440.1|DBSCAN-SWA
MPSPAPAPDGFTHADADVNGVRLHYVIGGSGPAVVLIHGWPFSWIEWRTVMPLLAEHGFTVIAPDLRGSGDSSIPAGHWTKRDEAEDLHQLMGRLGHDQAFVVGTDVGTMTAHAWAQAYPDEVARLVLSEAFLPGFGLEDHMNPATGGSWHFGFHAQSELAAMLTEGKEEAYLSGFWSMMSRGGITDADRTDLLRAYTAPDAMRGGFEHYATLVDDGRAARNSAPLAMPVLVLNGEFGLPQQVLLHGARQTARDVRADIVPAAAHTFAADNPAGAAQRLVPFFTSTPA
>NZ_CP047147|6257097:6386481|6310781_6311456_+|WP_159313431.1|DBSCAN-SWA
MTSAPDPQAPDAAPSGRPPRRHGADLTRAIQLATLAELADTSLEELSFERIAARAGAGKASLYRRWSTPAGLLLEALADPVSGFGDPPPQPRTGSLRTDLVRLLGAFADALDRPHGRALRPLLAQRARHPELYAEVYRRVVLPHKEILLGVLGAAVERGEAGPGALGVRTAATAPRLVIAAHMEHGTVPRDEVEALVDEVLMPLFTAGGGGNVPGPEERSTMGA
>NZ_CP047147|6257097:6386481|6332173_6332848_+|WP_159313438.1|DBSCAN-SWA
MIRVLLADDQPLVRAGLSALLNAEEDIAVVGVAANGAEALDMAVELAPDVACLDIRMPKMDGIDVAARLCGPDASPAVPVLILTTFDIDDYVFRALEAGVAGFLLKDSDPEEILRAIRHIVAGHGTLDRTLTRRIVAEYVQRRRLRPVTAARAIDILTARERDILLLLAQGMSNEQIAQALVVEVATVKSHLARLLPKLGVQSRLQAAVWAYQNRVVTVDDTRR
>NZ_CP047147|6257097:6386481|6280028_6280895_+|WP_037841730.1|DBSCAN-SWA
MNATAPVALQLARSRTAFVLVHGAWHSSAQWAATLQALARLGAAGYAVDLPGHGLDGPLPGGYLLPGQPGLLTERSPLASVTMDDCAEAVLQTLRAARRHHRVVLVAHSAGGGPAALAAERAPDLVDALVHLSAFVPAGRPRFLDYIEAPENATSRGHSLSLGDSAALGAVRINPLSPDPAYVEELRLAYYQDTPPGRFARWRAALGTDLPLSVPTTPVTLTPERWGSIPRTFLRCAEDQALTPAVQDLMIAETDRAMPGRRFTVRTLPGGHSPFAARPAELAAALLA
>NZ_CP047147|6257097:6386481|6325622_6326381_-|WP_107060924.1|transposase|DBSCAN-SWA
MVFVDRLLATLVHLRHGATHDVLACWFGVDRSTITRAVGEVRPLLAERGCTVSPDVRLRSLAEVIDHLGSSGTTGIVDGTEIRVRRPAAGRKDRDKFISGKNKQNAVKSMVVTDGEGHVLWCSPARPASCADITQARQLGLVRLLADGPPVEILADAGYQGLGAQTGGRVVTPPHRKFKKNAPDWYEEMHERQRKAHSSRRIRVEHGIAHLKNWRALARHLGRREHMSDTIQAVAGLLSHQQTVDLKPTRQT
>NZ_CP047147|6257097:6386481|6356983_6357973_-|WP_159313457.1|DBSCAN-SWA
MRTPTRLLRALSAPALACLLLPLTLTQRADAASAQADPIGMTSGYYVDPDSTPAVWATEHPDDGRASAIRSEIASRPMARWFGSWSGDIGSAVSSYVGAADAADKLPVLIAYNIPGRDACGGHSGGGAGTPDAYRSWISAFASAIGSRPALVVVEPDSLGDFSCLSQAQIAERNAMLKDALAQFNAHAPNTWTYLDAGNPAWISATTMAQHLDGAGARQAHGFSLNISNYFSTTENSAYGNAINQSLSASYGYTKPYVIDTSRNGHGSNGEWCNPGGRKTGPASQTGGGAEMLLWLKTPGESDGDCGVGAGSAPGQFLPEVAYKMIYGY
>NZ_CP047147|6257097:6386481|6365095_6365356_-|WP_159313463.1|DBSCAN-SWA
MFRRVTIAVAVVATAGLIAASPAAAHGDEGWNGGKEGAGHAKVEGGYGSGEFLNLGGPYGITYAEGHGAHFEGKAGYYYNHYLNRH
>NZ_CP047147|6257097:6386481|6376602_6377355_+|WP_159313467.1|DBSCAN-SWA
MLPADADRGDVGESAAGSDDELERGVRPIPLLGKAGLGFLGLGTLLGSLYAIQRVTFVVIHLSTDTSYPDLENFLSTLLKQAAVLSIAFGLCLPPLSVAVDYARSWDTLRRLRPLWRELTGAAPYVVLTTAVRRWRIPFRLERCVIEIEDASLALREYVSMNVYEKAQDFVRREGAPDEDVDAAAEAAWLRAAVQRTSAHQPLKEVEYPPLGVTDRDRVSELAWLLKVAKAYRSATVVEFCDSGQSFARQ
>NZ_CP047147|6257097:6386481|6268000_6269596_-|WP_159313412.1|tail|DBSCAN-SWA
MPSYLSPGVYVEEVASGSRPIEGVGTSVAAFVGLAPSGPLNEPTLVTNWTQYVAAFGDFTEGYFLAHSVYGFFNNGGSAAYVVRVGGSAEGTAGEAGPAAVTGTTAPAALPAAEPAQLGTFAVTALAPGTKGPLTVEVADPEGEGAAERFKLVVKDGGKAVETFDVSAKKGTRSYVVTQVKEQSKLISVTEAAPTGQLARPENQTVTPAAPPTAPAEPATAPATKNPANPGPAQYLGDSADRTGFGGLEAVDEISMVAVPDLMAAYQRGAIDLESVKAVQLGLIAHCELMGDRVAIIDPPPSQNAQQIRVWRQETAGYDSKYAALYYPWIKSFDPASGQARLIPPSGHVAGIWARNDSERGVHKAPANEVVRGAVDLELQITRGEQDLLNPIGVNCIRAFPGRGIRVWGARTLASDPAWRYLNIRRYFNYLEESILIGTQWVVFEPNDHNLWARIRRNISAFLVNEWRNGALFGQSPDEAYYVKCDQETNPPESVDLGRVVCEIGIAPVKPAEFVIFRLAQFSSGSGELEE
>NZ_CP047147|6257097:6386481|6298727_6300275_-|WP_159313424.1|DBSCAN-SWA
MHLSALLDSAVRSAGEKEAVVYGDRRWTYREFADGARRAATVLREAGLRPGDRLAVMTYNTPAFLFAAFGAWYAGATLVPVNHKLRTAEVERLLRHCGARLGVVDAEIGERATSAGVDVPWLVSHPDADEWSRPGDSFESRLALAEPWPEQEPGADDTVAQILYTSGTSGAPKGCVHTHRSIALTATYTAATIPLHRDERFLISMPIWHASPLNNWTMSTLLLGATVVLQREYDPRGMLETIQRERITALFGAPIALIAPLQTVPDLAAFDLTSVRAWIYGAGPLDADTARRLMKAYGSDNFHQVYGMSETGPVGASLSPAEQVAKAGAIGRGGMPGVDLRVVRTDGADAGAGETGEIWLRSDTRMVGYLDDEAATAAAFAGDWYRSGDLGRVDEDGFVTVVDRMKDVIITGGENVASQEVEGALRGHPDLLDVAVVGRPHPQWGETVVAVVVPREGTAPELAALREWLEPRIAPYKIPRELVLRPELPRTPSGKVTKHVLREELGRAATEAAKD
>NZ_CP047147|6257097:6386481|6267479_6267926_-|WP_003951816.1|tail|DBSCAN-SWA
MSLQPGDALTSHNFGLQIDGVMVEYLAEVSGLTLEQDVIKYQQNNGATGKAGVSLLPGTQKDGQCTVVRGMTQSASFTQWINDSINGRMATARKNASIIMMDFEDNPVKRYNLRNAWCSKIDTSTVKAGEAAALTESVTIVFEELVIE
>NZ_CP047147|6257097:6386481|6347561_6348230_-|WP_159313450.1|DBSCAN-SWA
MSRTTAPGPPSGGTPGRPLRADAERNRQRIIAAAQQVFAQRGIDVTLDDIAHHAGVGVGTVYRRFANREDLVEAIFDKEIQRIIDVAEEALTRTDPWDGLVHFFTTAGQDFADDRGLREVLLVGTHGKSRVADARDRLSPAISAVIERAQRHGSLRDDIEVTDFPLIQMMLGTATQYGRDVSPDLWQRYLTLILDGLRANREAPTPLPHRALSREEFERAAQ
>NZ_CP047147|6257097:6386481|6377375_6377966_+|WP_159313468.1|DBSCAN-SWA
MAANAAAESLLARQITDWLEPKNWIIAVTLLIGWHAAQWVGVAWGVIGALFAAVIPMAFIKHGIRKGRWGDRHVGAKRARLIVMAVILLSVSLGITLMVFFGAPSMMVALVVSMLVTLAILAAITFAWKISVHQAVSAGACAMLVQTYGPWMAFLFFLVAVVGWSRIELQDHTRNQVIAGTILGTVVAAAVFSLAK
>NZ_CP047147|6257097:6386481|6326685_6327456_-|WP_159313434.1|transposase|DBSCAN-SWA
MTGVITASEPSWIAPFSGLSPRQFGKLVTVLRREGADAVRKGRPWSLPLEDRALLVAAYWRTNLTMRQLAPQFGVSKSAADRIIDHLGPMLALQPRKRSAKDTVLIVDGTLVPTRDHTIAERSKNYRYSTNHQVVIDADTRLVVVVGRPLAGNRNDCKAWEESGAKAAVGKTLTIADGGYPGTGLVIPHRRERGQAGLPDWKEEHNKSHKQVRARVEHVFARMKTWKILRDCRLKGDGVHHAMLGIARMHNLALTG
>NZ_CP047147|6257097:6386481|6339238_6340105_+|WP_159313444.1|DBSCAN-SWA
MSSVHHRTATIDGHEIYYREAGPADAPVIVLLHGYPTSSFMFRELIPLLADDYHVIAPDHLGFGHSDAPPATEFDYTFDALAELTSGLLDQLGLNRYALYVQDYGAPIGWRLALKNPEHISAIVTQNGNGYEDGFVDSFWDGLWAYGANPGPDTEPAVRAAMSLEAIRWQYVHGVPDPSVVSPDTWEHDVALVSREGNDEIQLALFRDYQNNRPLYPLLHEYLRTSEVPVLAVWGRNDEIFGPAGARAFAGDAKNAEVHLINGGHFLLESHLDVVVGYLRGFLGQVLG
>NZ_CP047147|6257097:6386481|6308237_6309521_+|WP_030769295.1|DBSCAN-SWA
MSETPANTLQYRFDGPEDAPVLVLGPSLGTTWHMWDRQVPELARSWRVFRFDLPGHGGAPAHPAGSVAELADRVLAALDAAGVQRFGYAGCALGGAVGAELALRHPGRVASLALIAASPRFGTADEFRQRGVVVRSHGLDPVARAAPERWFTPGFAGAQPAITEWAVQMVRTTDPGCYIAACEALASFDIRPELGRIGVPTLVLVGSEDQVTGPAEARTLVAGIPDARLAVVPGASHLAPVEQPAAVTDLLVRHFSAPWSPAPEATGQILSPVPAPVVVPPQPTGPVAEIAPWVDPDAAVRPDPYESGIKVRREVLGDAHVDRELAEADGFSGEFQDFLTRYAWGEIWSRPGLDRRTRSCVALTALIASGHTAELPAQVRAALRNGLTVAELREVLLQAAVYCGVPAAEEAFRVARAVVAEETTPQE
>NZ_CP047147|6257097:6386481|6282897_6283770_+|WP_003951828.1|DBSCAN-SWA
MTTEHSHPHPRVRRGGPDDPTVDRSDPGPKVAEHHRAGTALARIPYPIEVRTLEVLARTWINPRMVRLTLGGPGLDGFHTHQADDHVKLVFPDPDGTLRPPVPAPGGMLTWPRPSPLSRVYTVRRYDAAARELDLDFVVHEGGHASGWAVSVPLGERITVAGPPGAKSFPHTYDHYLFAVDATALPALARWLEESPQDVSAQVVLETDEECEHAYPLAERPGVEVIRLTRAGGPSRLAGTVRGLPARPGRSFLFAAGESGDIKPLRAWSQDRCDALFTGYWKRGVAGLED
>NZ_CP047147|6257097:6386481|6312121_6312901_+|WP_018469051.1|DBSCAN-SWA
MRIATWNVNSITARLPRLLAWLESSGTDVLCIQETKTTEEAFPADALAELGYESAVRATGRWNGVAIVSRTGLADVVGGLPGGPEYDGVEEPRAISATCGPVRVWSVYVPNGREVGHPHFAYKLQWLKALRDAVADDAAGGRPFAVLGDYNIAPHDTDVWDPTAFIGATHVTPEEREALAALRATGLDDVVPRPLKYDQPFTYWDYRQLGFPKNRGMRIDLVYGNDPFRAAVSDAYVDREERKGKGASDHAPVVTDLTV
>NZ_CP047147|6257097:6386481|6278968_6279913_-|WP_003951824.1|DBSCAN-SWA
MEARHLRYAVALAEHAHFGRAATALGIAQPPLSKQIAALEREVGARLFDRTRRGVFPTAAGAAFLVRARAALAEIGAASVDAARAARGESGRLRLGFIASALLDPLPGVLRRFSRERPGVRLELHEMASSRSSAALAGGELDVAVTLGRPRGIGAERLVSVPVGHDHLVAVVGSGHPYAGLRSVAVAQLLHQPLILASGEDEPAVAAGLRDLLGEGSPALASATVARDVHTVIGLAACGVGVGLGPSRMLAAPRPGTWFCEVTPRTPLPDLVLSFSPEDRSPVLDAFLDVVRANCPVVGAALDRRLGPRSEAAG
>NZ_CP047147|6257097:6386481|6306203_6307079_+|WP_159313428.1|DBSCAN-SWA
MTTTPTGLPTMQETTYDIGGRKIFAAETGDGPPVLLLHGGGPGASGVANYARNVARLAGEYRVIVPDLPGYGRSTKGVDGSDPFGHLADGIRGLLDRLGLEKAHLVGNSYGGACALRLALDTPDRVGRMVLMGPGGIGTTRALPTAGLNSLLNYYTGDGPSRQRLEKFIRNHLVFNAADVPDAVIDERYQASVDPEVIASPPLRRPSGPDALRTLWKMDFTRDARLSRLPVPTLVLWGARDSVNRPSGGRMLAERLPNCDLYLVANTGHWVQFERAQLFNQLCADFLAGRR
>NZ_CP047147|6257097:6386481|6337996_6338323_-|WP_159313442.1|DBSCAN-SWA
MTVSDAYGTNSYTAKELAGLLADRLDVTFTERESDYLGVYFLATLADTTRLQIQPNAIPRDDGEDDLYDDEHPDMSTLLLITLPAADEPLSDELSAVGALTKIRSTRS
>NZ_CP047147|6257097:6386481|6358884_6359499_-|WP_159313458.1|DBSCAN-SWA
MVKDTSTGGRYHHGNLRAALLDSALAVLTEKGVTGFSMREAARRAGVSQSAPKYHFGDTRGLLGALATSAYRQLCDRLEGLDLTGLSVHERIQRVATQYVSFAGENRALFDLMWRMTRFDFTAPELAEQKHRALRALDHALRGEDAEPADDTDPALVPSYAVWSLVHGYATLALEGAIDSGSPDPLNSNLLPAMLTLLDMPDLP
>NZ_CP047147|6257097:6386481|6283759_6284761_+|WP_159313416.1|DBSCAN-SWA
MRTEPPRTALLFGVLVLLLAAAVASLAVGTRTVPPAEVWRALTDAPPGGGTTLAHHLVIREVRLPRTVIGVLVGAALAVSGALMQTLTRNALAEPGVLGVTGGAGFAVTLGAVAGLAGSQAAQLGLATLGALLAALLVYAVGRASPLRLVLAGTALGFVLAGFSLALRMTLPDVFDTYRFWVVGSLAGREQVPYLLPLLVIVAGLAGALLAARPLQALGLGTEVARTLGSRVRRTRITVLVLITVLAGAATALAGPIAFLGLMVPHLARRLAGGSVRLLLGLCMVLGPLVLLTADVAARLLLPTGEVPVAVVTAFLGGPVLIWAVRRYGAVTL
>NZ_CP047147|6257097:6386481|6266979_6267480_-|WP_003951815.1|DBSCAN-SWA
MRRTAAAAPGAAPSAAAAGADLPRPAPAAAPAPPEAPAPEQRERLRTEFPFELPRGYVDESGTVHRDGVMRLSTARDELVPLRDVRVQENPAYLSVVLLGRVITRLGELPMVHDGIVENMFASDLAFLQDFYRQINAEGHTRAGVRCPHCSEPFEVELGGSRLGES
>NZ_CP047147|6257097:6386481|6264950_6265409_+|WP_159313410.1|DBSCAN-SWA
MEGDGAEDDGAEDEGIEPLDEGEPDVVAALLAGAGPEGAAGGVGGAGRDEGAGPDGAAGSTGLPDLAGEACPVGEEPAVGEAPPGAPPTGPDPLAEFLAVARWTGRSGCDCAGVRPAGGAEAGRTAGAGAGEGVADSVLLPVPGTVGALAGR
>NZ_CP047147|6257097:6386481|6290535_6293154_+|WP_159313420.1|DBSCAN-SWA
MRTTGLRRHGRHLALLLTTALALTAFGVAPSGAASGDDEPVAAHGLKGEYYTHSAEGAFDFHELKATVFDPDIDFPSLDARLQSTTGQADDVSVRWTGKLVPEKTGATTFSMTGDNGFRLWVDDELVIDHWVDDWDKEQISDEVELTAGEEVDIKVEYFEHFGGSSLRLRWTEPGGQKEPVPSSAFRLPDDWEYNGAIGSTVQADGRTLKLDFARKPGPLPAGLENHLTAVIGGAKWPLDGVKPDPDDPRALLVGLAEPVVGNKNGDAPGNADLTYDGEGGLVQSDGTPVDAFWTSGDNHSTHQLTTRWGDEVTPANAHREYPRPQLTRGEWRNLNGTWQFAGAKEGERPPVGRKLGEKILVPYPVESQLSGIERHEDRMWYRRTFTVPADWKIGQRQRLRLNFGAVDWKSEVYVNGKKVAGHEGGYDKFSADVTDALKPGRTQELIVGVYDPTDADSGENPPMGKQRLDPSGIWYTPSSGIWQTVWMEPVAADHVDDLKLTPDVAKEQLTVETEGVRDGLPVKADVYAGKRKIATATGTSGTPLTVKIKNPHLWSPDDPYLYDLKVSVGKDRVGSYFGMRTISVEKVNGTPRTLLNGEPVFLMATLDQGFWPDGLHTAPSDEALAYDLKLHKKLGFNSVRKHIKVEPDRWFHWADKLGLLVWQDMPSMEAGRNPGQAARAQFEREMKTMIDQHRNHPSVVMWVTLNEGWGQYDEARLADQAKSWDPNRLVNAMSGINLGVDGGTGDILDEHGYPSPALPPEPDGERAMVTGEYGGLGLAVPGHAWAVQQSYVDVDPATYTDDYLEKLDEVRQLACEGSNGAVYTQISDVEGELNGLATYDRRVVKPDVKRVHDAHRALIRDASQDTVPNCS
>NZ_CP047147|6257097:6386481|6278479_6278959_-|WP_159313415.1|DBSCAN-SWA
MSDDWRTDRVGSALRGENPTVLRRLTAGFAVIGDVQFLPGYSVLLADDPAVDRLSDLPRPRRLEFLSDMDRLGEAVERACARADSAFLRVNLEILGNTDGFLHAHVWPRYAWEPAELVRLPVWLHPRDRWSDRRYALGPGHEVLREAIGDELDRTALAT
>NZ_CP047147|6257097:6386481|6307075_6308095_+|WP_159313429.1|DBSCAN-SWA
MNTEAPRTGSVFGAVHLGYLVIETNRFADWRRFGTDAIGMHHDALSRDLMRFRLDDQECRFLLRRGPAEDVVATGWHIDDHASFEQIEARVRAHGVPVVRGSDEEAALRGVERLLRFPGPKGITQEIYTTPVTSAEPLRMLASGFVTGDSGMGHIALTSTRPTRIRGYFDTVFDARLTDYIDETISGVKLKIRFLRVNERHHSIAVAATRGLPIDPVRTRVQHLNIQAATLDDLAQSYQRVHELGFDMALSVGRHTNDKELSYYARTPSGFEWEVGWNPIVIDETTWEPATHQGISTWGHLPVGQTVVDRLAQFRAAARSLAHPEDTVPALSGPGIADD
>NZ_CP047147|6257097:6386481|6369450_6371097_-|WP_159313466.1|DBSCAN-SWA
MSDRRLHRWYQALMKAVPQSLWVASPEGAVTVLSRGGIAEELWTPNPAASCIEALHPKDRDWFQRAWRRATQQRSPLDATIRVRLDGTDHFRHIKIFAAPVVDENGELEFFGTAADSEEHWRAQMRIKLLARMASVPAAHDLSEAFLTTAAAVVPELADAVAIFHVEDSEESGGHSSGVPAKNWPGHVGLAPGLPPLPPLDADFTLGPAARGAIEDQADRLLVFPPDGPPENGLSEVSVRWLREAHATGVALLPVVVDGRTVALAAVVTCQGNPPPDEADLSLLRDVFQQMSGPLRRTMELQSIRGRALALQQSFLTPPRTVDGLTISALYHPADSAAEIGGDWYDAVRLCADALALSIGDIAGHDLDAATAMGRVNSLLRGLAYDSGPTASPATTLSRLDRIVQALDGPSMITVVHAVIRRQAPRIWHVTLANAGHPPPLLIPRDTSPRYLHDLSAPDPPLCVADSLPRTDLHAVIREGDTLVFYTDGLVETPGTDIGDSLERLRERTEALVQAGVPLPALIPKLLPAIHNRRDDIAVIALQARSKP
>NZ_CP047147|6257097:6386481|6343509_6344571_+|WP_159313447.1|transposase|DBSCAN-SWA
MVWYGEIGEDRGRSGGKVPGAVATSGRASASAGYGGGGTVAGAWRHQDRLRIGTDHDTAAFAVASIRHGWQAVGRHDYPGARRLLITADGGGSNGCRTRGWKTQLADLAAETGLEITVCHLPAGTSKWNKSEYRLFSHITMNWRGRPLTSHEVMLQTIAATTSRTGLTVQAEFDSGEYPTGVRVSDDEITALPITRHRFHGDWNYTLHPQRPTGTATTTSTQDEAQPDGPARLTRRSLQDPELTGMTRRQLNELIDVLTPAMEIQREQVLDTRRGHGRLVAPGTGAKPKLTSADRVLATVLHLRKLATMISWASSSTPPPRPLAAQRKTSARSRKPTEFTSLPRPPASAHRLT
>NZ_CP047147|6257097:6386481|6381952_6382558_+|WP_159313471.1|DBSCAN-SWA
MENFFTPKKIWQGGGPFPHVLVLLSEYPEFREYARAHHELLSEYGDMLGVIPQEWLHSTVQGIHHAIDDGQLHQLRGTLRDELAGMEPFRVQLGPVWPGVTAVTVAVYPEDGMAELNSRVRTAMEKVPGITLRAPELRFWAHASLAYARQDFADRKLNRALRALRPPRVDITIDRVHLVNQYQRPDLGYYRWDVVEEVQFG
>NZ_CP047147|6257097:6386481|6315001_6315439_+|WP_003951849.1|DBSCAN-SWA
MHIPFLDKWRERQSGPGRSAAAVFEDHPDAAADLFAECELLRSHAQVAGLELDDTPASLAALDQLLPRWRDDPEVLPWLGNDAGLYLGTVVVRTVPGARWHVWPGGRVVVRLPSGRELHVVEAGVEWAVHGAPELSQMYAEISEG
>NZ_CP047147|6257097:6386481|6324151_6325024_-|WP_159313992.1|DBSCAN-SWA
MIVPASGTITGSPSGYCRSGNSHDGFDIAGPTGASVKASADGTVRQSDKAASPGNRVVIDHAGGWETRYLHLNSRAVSTGQKVKKGQVIGTIGSTGHSTGPHLHFQVERNDVVIRDSSLLNNFRCGSAVSQGRTISYSFPGLPGGGGVVDAYPKLREGDRGDAVKSLQAHLVTAGHSVEKDGVFGAKTLAAVKAFQKKIGTGADGVVGPKTWGALLTAPAKGTKLREGSTGTEVKYLQRGLNATLGRSLDVDGKLGAASKAAVIAYQKSRGLAADGVVGPTTWSALKSGK
>NZ_CP047147|6257097:6386481|6284757_6285840_+|WP_159313417.1|DBSCAN-SWA
MKVEEKRAREDRAPETGSRVVARPPLAVRIGRFSAAVERRGAVAAVVLAAVAAVLAFVGLCRGDAWDAPGEVFAALAGHGDAAFVVQEWRLPRVTAALAFGAALGAAGAVFQNLTRNPLGSPDVIGLDAGAYTGALVALTVLSGTSVQLAVGSVAGGLAAAVVVYLLSLGSGLGGLRLVVIGIAVNAMLTALNSWIVLRAELEVAMAAVGWSAGSLNGIGWEDLRLPLAILAALAVLLAALARPMHQVAVGDDLAVTSGVRLSGYRPLVVLAGVGCTATVTAVAGPVVFIALAAPQIGRRLAGAAGVPLLPAALTGAVLLLVADLTAQTVLAPVALPVGAVTTVVGGGYLLWLLVREVRR
>NZ_CP047147|6257097:6386481|6317948_6318821_+|WP_015506817.1|DBSCAN-SWA
MTATSEQEPSALYDVPGPKARKRHRIFGVLATLAIAAILGWILYLLFDTDQFTTAKWRPFAYTGIQELLLRGLGNTLKAFAYASVLSLVLGGVLAVGRLSDHRPVRWVATVIVEFFRAMPVLVMIFFVFVALQVQALPALVTGLTLYNGSVLAEVFRSGVNSVDKGQREAAYALGMRKTQVMVQVLAPQALRAMLPAIISQLVVALKDTSLGYLITYEEFLHAGKLIASNLDYDLPFIPVVMVISPIYIGMCMLLSWFAQWVSRRQRRDPKAKAAAVTRAEPGGLLPGER
>NZ_CP047147|6257097:6386481|6336634_6337105_+|WP_159313441.1|DBSCAN-SWA
MPADAAPLSPDELRLWQSLGRLVHSLPRVLEDDMSRTGVTMTEFAALLLLSEAPDHRMRMSALADAAGLTPSRITRVVDGLAKHGLVRKERHGHDGRGNDAILTEAGLRTMREAQPAHLASARTRVLDQIPPDQISALAQTLAAIAERLSTHRRDA
>NZ_CP047147|6257097:6386481|6257097_6257661_-|WP_010641036.1|tail|DBSCAN-SWA
MSARGSVDGLESSAPLSAMLPAVFADDDLAQRFVAGLDEVLAPILNTLDCLDSYFDPALTPADFARWLGTWIGAETDGTEPDPRLRAIVAATARLHRIRGTRQGLAETVRLAFGTTPEITESGGAAWSARPLGPFPGPARPALHVALRLPDPTPADTHRLDALVAAARPAHMPYTVEVTAAERTSER
>NZ_CP047147|6257097:6386481|6300351_6300960_+|WP_003951838.1|DBSCAN-SWA
MAYRKTPAEISRLEAARDHLVVRATEVVAEVGWAQASVTAVADAAGIAAGSVYQHFPSKAALAVEVFRRAAGREVEVLGEVLHGPGDPVGRLARGTEVFARRALENRGLAYALLAAPAEPAVGAERLDFRRRYRALFAAVVREGIAAGALPPQNAEITAAALTGAIGEVLVDPLAAPDENATEALLADLTGTALRCAGAPAT
>NZ_CP047147|6257097:6386481|6312914_6314705_-|WP_008415979.1|DBSCAN-SWA
MRRQLWGPALVLALITSAASLTSAGAAEEQEPRPLRELYDNRAVSEDGRPGAADFDGQGRSLPAAALRAAGWQIGARPAVEGTRLDWPVSRPGRPDNVRAHGQRVAVEGRGDALTFLVAGTGGEATGVGTVHYRDGGHSRYRLTAPDWRTGPLATKAVALPYLNSREGRVADRPRLYVVTVPLDAGRTVESVRLPHVRGLGRSLHVFDLRVRPAAEGWTGSWSASTAGLPEVGPWRDQTLRLVVNPTKSGPTARVRLSNTFAGTPVRVGSATVAVRAEGAEPRSTPVPLTFGGQESTVLPAGAEAVSDPVGLAVEEGADLLVSLHLPGAVPSVPLHDKAVQKSYLSTPGDHAADADGAAYTGTVGTWPLLTGVDVSGGPGSVVVLGDSITEGVGTTEGANKRWTDALARRLRDQDRVPRYGVLNQGISANRVLSDRYPGDGVSSDTGGVSALHRLDRDLLSQTSVRTVVLFEGINDVRWGARADEVVDGLRQLAERARARGVRAVVTTLAPCEGESRCTPAVDAERTEINRALRADRDSFDAVLDFDRVLRDPDRPARMLPAYDSGDHLHPGEAGLQALADAVDLTVLDGRRGRTR
>NZ_CP047147|6257097:6386481|6304582_6306190_+|WP_159313427.1|DBSCAN-SWA
MSETGAGAGTEDDAYDVAVIGYGPTGVTAANLLGAMGLRVVVVERDAAVFSRARAISTDEEVVRIWQRTGLAERLKQDMLTERDVDFVDADGRSFLSARPTPRGHGHPPQMFIYQPALEQVLRDGVDRYPNVRILLRHECLRLRQDADGVELTVVGTADDSVHRLRASYVIAADGGSSLTRAQLNIGYEGTTYEDRWVVIDTKMLKPWPDHDKLRFHCDPARPAVDCPTPLGHHRWEFPILPGDDEQQLTTDDAVYRLVARYGISRDSIEVLRATVYSHHVRFATRFRAGRVFLAGDAAHAMPPWIGQGMAAGVRDVANLCWKLDAVLRGELPGSVLDSYEAERKPHVKEVTRRAVFVGRIITERRRPVSRVRNGLLRALDRVPRFGDRTQDSHWIPVARYGAGLQARPRTKATGHQIPQPWVTGPDGLRVRLDDALGGRWVLLRAGTPTPQPAWDLPGVSALTVTPAGSQPAAGTLVDSDGVLLPWMTRHGAATLALRPDAYVYAAAPAGAALPPPPRGFTPPTAAPLDATTAQ
>NZ_CP047147|6257097:6386481|6385377_6386481_-|WP_159313474.1|integrase|DBSCAN-SWA
MMRRPTTGLAGSANLELVSGALRFRPEDTVWEAMLSGWRSQQQARNLKKGTYEPREKLVRAFHTHTNEYPWHWTPAHMDEWSANLTSEKGLAPSTVRGYQGTVRLFSEYLIDPRYDWARACEEQFGTYPVAIAHEWNTIPHLQDYEGDPEARPFTREELQLFLDYADDQVERAIRSGRKGTLAAYRDATLFKVIYGWGLRRTETSKLDLVDFGRNPKTPQFGRYGTLNVRYGKAKKGQPPRRRNVLSVMDWAVESVEDYVENVRPRFGFPDQPALWITERGGRLRPGSINDRFVEYRDTLGLPKELCPHSLRHSYVTHQTEDGVDRMFIQQQVGHECDSSLAIYTHVSSDFMNTSLQNALAPAFAGL
>NZ_CP047147|6257097:6386481|6275250_6278142_+|WP_159313413.1|DBSCAN-SWA
MTRPPREHPHHDGPLAAEIERARSGSGRLVLLRGATGTGRTTALDAAVRAAAARGLRVLRARCSPEDTGVPLAAVRQLLSPEDEFADLVPEGDERGTAARLWRTLRTYAAEAPLLVAVDDVHLADDPSRRWLLDAARRLDRLPLLLVATERSQYDIEPRPPGLAQSLAPSLVRTRTVAPLGDEAAAALVREAFPAAGEVWAEACVRAGAGVPLFLHALLDDLGATPWPEPDAPAADGVPALPESCAALYPGSYPAAVSWWLENAGAATAEVARCLAALEEAWPSPSAAGDTGTDAPPEPPHPSVRERPPTAGGSGAAARDPAGLLAEAAGADPARVAGWLAAMGRLGLLRTDAAGRPRYAHPLLRDAVLTGWPLRRRQAAHRAAAEAMTRRGDRVEEVARHLLRVPAAGPPWALRVLRDAATVAVHDARPYDAVGYLRRALEEELTGDLRQRLLTQLGSLEYASADAPAAIARLAEAQHLPAGPRDRVRTAVALGAALAARGEIRTAMEVLRRAGGSLSGHPGLARTVRAASALVSDGDLASRQEVYRRLCETGERSPELVGTAGQALLVRYAATAGLVSAPEAMRRMRELLAQPTDPLAEPFLVGTAAAVAQWADELDEADRLVERGLAGQHPGLLHPMLAALLNTGSDIAAARGDHARLLASGLAGRQGEPRAVPTNQDAHVLMALVHTGRTDEARGFAGRFDLNSAPDGWEVNRFLYARGVLRSATGDPAGAVHDFLECGRRQSAREVVSPVVTPWRSAVAACRLELGGGQEALDLATEEVRLARVWGTPRTVGRALSVLGTATGGRHGLELAEEAVDTLREVPGDPLAELIPALLAQGRQLVAAGERGRGRVRLREAAELAERSGAVRWLGLASQALREGGARHPAAARTGSVALTDSEHRIATLAAEGHTNTEIADLLHLARRTVETHLTSTYRKLGIRRRTELPGRLERGPTRAPRP
>NZ_CP047147|6257097:6386481|6278169_6278487_+|WP_159313414.1|DBSCAN-SWA
MAVSLVELRSRLRRSDRPAAFAVVVGDLLLCCAVLWWMVAGAGATTREEETASWILGAKVYGIWLAAGMVLFAGAGLPRTLLGHLAAMLLTPSALFLLVMLLSLR
>NZ_CP047147|6257097:6386481|6269968_6271309_+|WP_015506831.1|DBSCAN-SWA
MRLRVRNTGDVVDEYRFEPVGALAPWTRVEPQTLRLYPGTTGTVELTFSPPRTPDAVAGPNPYAVRITPTEHPEAVTVPEGNITVSPFTEVRAELVPVTVKGRFRGRPRLAVDNLGNTKVTASVSGSDNGDHLSYEIRPQNVQIEPGRAAFVDTVVRPRQKIWFGSKEERPFTLTLRRSGAEPGEVEGTYVQRGFLPRWLATFLGIFMALAIAFVMIWIAYKPQVRTSATEQAAAADALAPSPTPDPPSQAPPPEPEPEPSEEPAGGADGGGGGEPSPTEEPGVVPAERVLLRNTTTGYCADVPDRGKGKINERVQQATCHETGDNQLWDLVVTQEKGGPNGAPLFLIRNTMDRLCMDLPKFGPQPIRTPISEFTCDGTMNDNQLWWAQELDNGAYWIRNAVSNNLCLEVAGSGDGKIGARLLIFTCTLTDDQEWEIMPTQQKTGS
>NZ_CP047147|6257097:6386481|6293231_6295643_+|WP_159313421.1|DBSCAN-SWA
MTLTRRTVLRSSTAVAAAALAGVGAGTAEARPRPARAEGAVAPDAFTRLPPGSITAHGWLAGQLRLQLDGLCGRFAETSHFLAMDTCGWVHPELGAWEELPYWLRGYVPLAIATQDATALATCERWIDAILATQEADGFFGPRALRTGLDDGPDFWPFLPLLMALRTWQEYTDDTRIVPFLSRFLRYMADQGESAFDSSWVSVRWGDGIDTARWLHDRTGDAFLAGLVEKMHRFGADWTGTALPTPHNVDISQGFREPAQYAQWTTDGADALTRATYRTYDQVLASHGQFPGGGIAGDENLRPGFGDPRQGFESCGIVEFMASHELLTRITGDPVWADRCEELAFNMLPAALDPQGKAIHYVTSANGVHLDNVRKSDGQFQNSFAMQSFRAGVDQYRCCPHNYGMGWPYFTEELWLAADGGLVAAMYADCEVRAEVGDGVGATVRERTEYPFDETVTLTIGVESPVAFPLRLRVPGWCEAPRLTVNGEAVPVSGGPRYAEIRRTWHDGDEVVLRLPQRTTLRTWSGNHDSVSVDHGPLTYSLRIEERYVRTGGSDPFPEYDVHAASAWNYGLVPDGSFTLHRARGARDGNPFTLEGTPVTLTARARRIPEWTADHEQVVAPLQQSPARSRAAVEEVTLVPMGAARLRITAFPMAAPTGHPWTPEPPYHRILNKHSDKVLAVDGMSTANDARVVQFDNAGTGDHAWQLLPAPGGALRLRNGQSGKYLAVRDSSTADSALAVQYEDTGRPDLLWTREDQGDGWFLLRNAHSGKVLGVHEMATGNSAQVVQYTDNGTEDHLWRLTD
>NZ_CP047147|6257097:6386481|6259615_6260077_-|WP_003951807.1|DBSCAN-SWA
MSEQFVGSGWAFPLRIGPTGGIALVSGEREIEESIRLVLATAPGERPMRPEFGCAIHDLVFAPVNEQTAGRIQHEVLTSLDRWEPRIEVHDVEVTAGHDRSVLFIDVRYAIRGTNNPRSLVFPFYVIPSHDEPGTPGGAAGPNGPGTLPESER
>NZ_CP047147|6257097:6386481|6318872_6320468_-|WP_159313432.1|DBSCAN-SWA
MRRPRPALTTTAACALTAALAVGTLSAPAHAAPDGPAKAQAGTSASGIRFVDITSTDGTVLKANVVTPAGSAAGDRHPVIVLPTSWAVPQIEYLAQATQLADSGYVVVSYNSRGFWQSGGEIEVAGPPDIADASAVIDWALANTPADPERVGMAGVSYGAGISLLAAAHDPRIKTVAALSGWADLIDSIYSGRTQHLQAALLLGGSGLITGRPSAELKEILGDFIGSNLDKEQQMIDWGKKRSPATHLDALNANGTAVMLGNAWGDSLFPPNQYADFYEKLTGPKRLEFRPGDHATSEATGLLGLPNDTWTSARRWFDHHLKGEENGVDREQPVRIKSRSTGAYESYPDWKSVGADSRKIDLAGTHTIRANVDSGANGGIIFLTNALDQLIRTPPMASMPLLPRRYAAVWQSERYSGGAAVRGTPEVHTTVTPTKSSGTFVAYLYDVGPLGVGKLVTHAPYTFHDREPGRPFAVDLELYSTAYDVPAGHRLAVVVDTVDPLYIEHNPSGAQLTFSSPADDPGHVSVPVREK
>NZ_CP047147|6257097:6386481|6349917_6351129_+|WP_159313452.1|DBSCAN-SWA
MNKPRALIVGMGIGGLATAMRLHEIGWEPVLVERSPARRAAGYFIGLFETGRATAERMGVLDAIGNRTDPASVTYDIDREGRRRPGMGYGDLPGEPRLILRGDIEAALYDQVASKTEIRYGTTPLALDEHPHGVDVTLATTTGENTTETTERFGLVVGADGLRSTVRRLVFGPDSDYLKPFHHIIGATVLKEAVPGFRPNDGLVLAEPGRSVWVFPFTDHQPGVLFNYRTDDEDAQFRRPPTESLRCAFGPEPTGPVLENLLTQFEHADDALFDSTHQVVMPTWHTNRVVLLGDSAWCLTLYSGMGASSSLAGADFLGTTLQRNPDNVPRALREYDQRLRPFIATQQHLGRKEGLPMFVPQTRREITTRSLIQKLTSNPVGKRVMKTVIAGKFKSKSLDIAAP
>NZ_CP047147|6257097:6386481|6273399_6274071_-|WP_003951819.1|DBSCAN-SWA
MIHEVDEVLKGLFGTGVLAGSGIDVSFEAPTRDWAARRNAPVVNAYLYDIREDVARRQRGQEPVRDAADIVVRRRRPPRWFRLSYLVTAWTKTPQDEHRLLSAVLATLLPREVLPPAELPGALGALGLSVPLTVAGIQTESRSLAEIWSALGGELKPSVDLVVTVPFPSYPEYDAGPPVTEGATVRLRGVNGDPPRSGERSHRPRQVAAVRAAREAARRRRGS
>NZ_CP047147|6257097:6386481|6340713_6341760_-|WP_159313445.1|DBSCAN-SWA
MRKGKPRFRYLAAAVVALAAVIAAPAEAAPGLVPAADREVVFTADGTTVYGTLHVPEHRAGQRLRAALLLPGSGPTDRDGNQPPAFSPDTLAQLTDALDEEGIATLRFDKYGTGRTGLGAYRDHPEDLDYPAFVRQARAAYESLRDQPETDPHRLLLVGHSEGAMTGLVLGGTVRPRPVGLALLQPQAIRMLDLVSLQLKAQVAEATRQGQLTPEQQRTVNAAIDAAITSLREHRPVDTTDLPAEIAQLFEAFQGTSARFVVSDDAVNPPDIARTLRPGTRVLLTCGTNDPQVPCATTNALTNALRHAYAGRPGRVTLPAVDHLMHDPDHPDTLAPSVLDALRRLTRH
>NZ_CP047147|6257097:6386481|6362698_6363964_+|WP_159313462.1|DBSCAN-SWA
MSDSLPPLSGASLASRMASVATAGLRDVADRLHTALREVWPHDALVIFTKECTGRPRKKAGDPLITEGVTISELDSLRDWASPGLWTGEAVLGGRTRSVALLGADTGALLVLCGPRDPVVTDGPAHARALWDVASVCIAHLVAEARPDYLRESRAATHERLEVTAELTDRHSTDLESLLAVLRGRNLDDSTARAQAIDLAADALIRTRTGGDLVVSIAEEPVVTAFERLRSDLSPLSRYQSLQIQFVEPPSDGRALPGEVAHAARAIVRSTVLLMREQEDVTRVRVQWNCDGTNLLVSVRDDGPGRLNRELPAVRQLVARAASLGGLLDLEAIDNWGSRVEVRLPLDASQPLEQLPGSWGLRPREIEVLRLLTAGQRNRQIAARMGISENTVKFHTSRIYRKLGVTSRAAAATVAAEAGLR
>NZ_CP047147|6257097:6386481|6359569_6360589_+|WP_159313459.1|DBSCAN-SWA
MTDKVLVTGVSGFIGGHLAATLLRRGYAVRGSVRSPSRIGEVHDAMAAAGVGSADLEICRLDLLSDQGWAEAVEGCRYVLHVASPFVLEKPKNPDDLIRPAVEGATRAVTAALDGGAERVVMTSALATMQFARAPKGHLYTEADRTDPDDPRLNAYTVSKIKAERAALERAQRYGAPERLAVVNPGAVIGPLLTDDPGTSITAIQQIMSGALPMIPDLRLPWVDVRDVADVHIAAMSSANAGGRRTIIATDPMSLIDVAQVIRERLPQASHKVPARAMPTWFTWLASAFQPQLRDNRWLIGQNQRFDRTPAETLLGRPLHPIPEAIQETGRSLAERHLI
>NZ_CP047147|6257097:6386481|6334746_6335652_-|WP_159313439.1|DBSCAN-SWA
MQILVIGATGYAGRRVSAALARAGHTVLGLARDTASPASRDLAVNEVTPVQGDFSKPDTWRGHLDDTDAVVHLLMDMNDPVGADQRLFTELAAAQERDGRHRHLVFTTGISSYGRTGLPLMDENTSGNPESPIGFRFALEKELAATGLAHTVVRPGFMYGGPATTSMTGQWFAAAEAGNPVFYGDTAKRWSWVHVDDLADAYVRILDNPAAVDGEVFVIADDQRLTALDMQHAAVRAAGHTGEIALESAEAGGMMQMAADQDELVTSAKAHRLLGWRPRHASFTDAPHQYYRAWKAAQPTT
>NZ_CP047147|6257097:6386481|6315598_6316342_+|WP_003951850.1|DBSCAN-SWA
MAVDPLIELHDVNKYYGDLHVLKDINLTVGRGEVVVVIGPSGSGKSTLCRTVNRLETIQSGTIRLDGQPLPEEGKALAGLRAEVGMVFQAFNLFAHKTVLQNVSLAQMKVRSRKRPEADRRSRELLERVGLAEHADKLPAQLSGGQQQRVAIARALAMDPKALLFDEPTSALDPEMITEVLEVMQQLAREGMTMVVVTHEMGFARSAANRVVFMDGGRIVEDRTPEDFFSNPESDRAKDFLSKILKH
>NZ_CP047147|6257097:6386481|6274230_6274839_-|WP_008412680.1|DBSCAN-SWA
MPVAVVAADPISKEGAVSQLRRQPEVELREESAPGTVALVVENALDENAVGRLRRIVRGEGARAALVVGTLQERELLDVVECGVGAIVWRHEATARRLVSAVLAASRGDGDLPADLLGSLLSQVGTLHRGAVGQQGGPSLGLTPREVDVVRLIAEGLDTGEIAGKLSYSERTVKNVIHGVTTRLHLRNRAHAVAFALREGYI
>NZ_CP047147|6257097:6386481|6348328_6349837_+|WP_159313451.1|DBSCAN-SWA
MEIAVTAVTNEVRPPRADRAPERHHGRRWLILAVIAIAQLMVVLDATIVNIALPSAQADLGFSNDSRQWVVTAYSLAFGSLLLIGGRIADLIGRKVTLVIGLVGFAAASAVAGAATNFEVLVAGRALQGVFGALLAPTALALLTTTFTDVKERATAFGIFGAVAGAGGGIGLLLGGVLTEHLNWRWCLYVNLIFAAVALIGALFLLPRHRPDKSVKIDLPGTVTATAGLFALVYGFANAEHEGWSSAGTWAFLAVGVLLITVFVRIQARVAHPLLPLRVLLDRNRGAASIAMFISAAGMFGVNLFLTYYLQQTLRYSPVETGLAFLPMVGAVMIGTTLSSSVLNQRFGPKPIVPIGMALSAVGLTWLTGLDASSTYAAHVLPPLLLFGLGMGLVMAPAMSAATSGIDPADAGVGSASVNTMQQIGGSIGTALLSSLAAGAATDFLAGKEATPDLVAQSTLQSYSTAYEWSAALFAAGMVICGLLFRRGAPVHDPRAAHTVHM
>NZ_CP047147|6257097:6386481|6316354_6317293_+|WP_127451644.1|DBSCAN-SWA
MTHTDPHRRPGRAVRLPALALLVLLALVAACGKEGSPPVKGPRADQLPDYRVDTGFSLPESPTWRKAKARGALIVGAKEDQPYLGEKDPAGGGYTGFDIEIAKMVGAHLGFAENRVRFTTIASANRETALQNGQIDYYVGTYTINDNRKRLVGFAGPYYVAGQGLLVRTDEEDIKGPEDLDGKRVCSAAGSTPYQRMQEEYPKAVLVSYDTYSICVDNLLTYQVDAVTTDDAILLGYAAKVPEELKVVGKPFSEEPYGIGVLRSDNALRLAIDDALEEGERKGYWKAAYDATLGLSGVPAPKPPAIDRYAAG
>NZ_CP047147|6257097:6386481|6271342_6273400_-|WP_030769340.1|DBSCAN-SWA
MTAYDPPLPGLAEDVPDAAAPALLARLAVLRDGVAALVARRAAGDPTAEDPLRGLYVSDEAARQLLDRWRPEEEAEGSEESGAPAPGAVAAGAHPDGAPGDRLARLALRAGLTGLDTALLLIALAPDVDRGVEPLYGYLNDDVSRRRATAGLALELCGVPTSQAAARARLHASAPLRAWGLLEVEEPERPFLTRSLRVPDRVAGHLLGDDTPDAALLGLLQPLPPPLPQDPEATEFTRLLAARLGAGPVTAYLREPREGDGLAVLAAALPAAGLSALSCLAAEERVPELLREARLTGRPLVVPGLPERPGPLVRALTAAPDVTVLLTDRRPYDPEWSPADVLVLDAPGRRAGGTAAWRAALGADADGFDLAAAVAPYRLGGDRVRRAARAARALAEFEGAPVGAAHVRRAARRQSASGLEQHARRIRPAVDWDDLVLPEGPLSQLRELALRARHRDRVLGEWRLNAGGGRGRGVLGLFAGESGTGKTLSAEVVAADLGLDLYVVQLSSVVDKYVGETEKNLERIFTEADRTDAVLLFDEADAVFGKRSEVKDAHDRYANMESAYLLQRLESFEGIALLTTNLRANIDEAFTRRLDLVVDFPFPDAGQRLALWRHGLSHVPHEEGTDPAELAREFELAGGSIRSAVVTAAYLAAGRGTPVSGGDLLEGARREYRKAGRLVPGEGGW
>NZ_CP047147|6257097:6386481|6303810_6304443_-|WP_033238272.1|DBSCAN-SWA
MTEPRTARKKRANGVESRQRILDAAVEIAGERGYEGTSIAAVSAACGLPASSIYWHFKDKDDLIAAVIERSFDTWLAAFELPGEETGTPRERVTAVAGNVAKSLVDAPDFLRLGLMLALERRPCEPRGRTVFLQVRDIACARIAEMAQTLVPGLDEESVRILTTYAVAGADGLFVQREINGDAVDLVAMLELHAQLVYDAATRMVTPGEA
>NZ_CP047147|6257097:6386481|6378464_6379607_-|WP_159313469.1|DBSCAN-SWA
MAADSPTTWDELLAGPFNIHSVSTHNSLLLAAMRDTFNLTDDAFHRMMRADHLRLTRALDDLGIAYSSLAKALIPDHRRREIVLLFDSAVASLSSNGFYGIDVAEAWVAGLPRPRKGFPVNSILRGDILHDSADEVQAAMDKSVVYHRPFTVIHPSQVYCVYVTNLSKDQANALTSSAAEHPAYVGYADCTDRSVLKTHLGLSLMNSGLRVGDMILEGVSEIGAEPNGAGLPLEALGFTPTAVIDTLFLPFLGYRINSHLTGQNREDNRSALATLSPDAAHLESPDIWMTPGRYGYLQDGKHRISVEQAGLLHLDQPALEAAVSKLVAQGHLYNLRLDGYGNLLYTALVDVEVEDGRYRTFTIGLRFNPEDKRVELTTFF
>NZ_CP047147|6257097:6386481|6317307_6317952_+|WP_030769285.1|DBSCAN-SWA
MNVLTDNFSTYGKGFLGTVELTVYASLLALVLGFLMASFRVAPVASLRFFGTAWVTVLRNTPLTLLFFAVLLGLPRFGLVLPFQLFAVLALGCYTSAFICEALRSGINTVPRGQGEAARSLGMTFGQTLSAVVLPQAFRSVIAPVGSTLIALAKNSAIAGAFSVTELLGTYRTLSELGYNIIWTFVWIALGYLIITLTISALFHLMEKRWGVAR
>NZ_CP047147|6257097:6386481|6328864_6329674_-|WP_159313436.1|transposase|DBSCAN-SWA
MRADLVPDDLWERVAPLLPSAPERRHRYPGRLRVPDRAALAGVLYVLRTGVAWRDVPAETVGCSGVMAWRRLRDWTEAGVWPRLHAALLTELRRADLLDLDYCSMDGSHVRALKRGDHVGPSPVDRARPGSKHHLIVDRHGTPLAVTLTGGNRHDVTRLLPLLDAVPPIRGRRGRPRRKPRRLYADRGYDFDKYRRLLWKQGIKPLIARRGVAHGSGLGKVRWVVERAFAWLHQFKRLRIRYERRADLRQGLLELACSLICLRRLRASS
>NZ_CP047147|6257097:6386481|6328457_6328859_+|WP_159313435.1|DBSCAN-SWA
MERVGAARDLVLAYVHDLNAIDEAVRVAIPSLERLADVLGLARSRQINRSGHVGTYSYTVHGAGCRFVCDNGTEVDVDFAADGGEVFDLWRLRWYGLSLPEPLDVTDQDLRSAVRSLQPLLTEVRPGWFSVAN
>NZ_CP047147|6257097:6386481|6352156_6353038_-|WP_159313454.1|DBSCAN-SWA
MSELGEYLRACRARVSTEQAGLPSSGHRRVPGLRREELATLAGVSVDYIIRLEQGRAKSASPEILTALARALDLGTDEQEYLLRCAADSTGLTNKADSHAPRAQRVSPATRVLLDSMPGVPALVLGRRMDILAWNTLGAALITDFGQVPVQHRNHIWLSFLDPKVRALYTDWEKVARECVSYLRMDAGRYPEDPALARLVGELSVKDADFGQWWSTHRVRALRSGRKDFLHPLAGEITLDFQVMDVRGNGDQTLLAYTAEPHSRSAQALSFLAGWAIAEKNTAVDIAVDTPPR
>NZ_CP047147|6257097:6386481|6262039_6262762_-|WP_003951809.1|DBSCAN-SWA
MAKSSKGAGKSLVRASLSIHEPPRGKSTTPGGLIRTFHFDFNPAQLTISRGANWKFTPSPAVRKGSKPEFLGPEPREMTVEVFLDSSGEPTGNTVLKKVEALLGCCETTARSIAAKQPSPPWVVFEWGAFSTARFTAYVSSVEASYTLFGTTGVPIRATCQMRLHEIPSKTKGQNPTSGALTAQRVHRVVAGDTLQSLAWREYGEASAWRAIAEANNIDDPSRLRSGTELVLPAAEEVRR
>NZ_CP047147|6257097:6386481|6285920_6286694_+|WP_010641004.1|DBSCAN-SWA
MPRLTADALELAYGDRVVAPRLTLDIPDGAFTAVVGANACGKSTLLKALVRLLTPNSGTVRWDGEDLHALRPKTVARRLGFLPQGLTAPENTLVRQLVARGRYPHQSLLATWSPADEQAVADAMAAAGVAELAERRVEELSGGQRQRVWVAMVLAQETPYLLLDEPTTFLDLAHQYQLLRLLARLRDEGRTVVAVLHDLNQACRFADHLVAMRGGRVVAQGAPADIVDAALVEAVFDLECVVVPDPVTGTPMVVPHA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010641036.1|6257097_6257661_-|tail	tail protein	NA	NA	NA	NA
WP_003951806.1|6257657_6259616_-|plate	putative baseplate assembly protein	NA	NA	NA	NA
WP_003951807.1|6259615_6260077_-	GPW/gp25 family protein	A0A1D8KR06	Synechococcus_phage	8.0e-11	29.5
WP_008411668.1|6260135_6262040_-	VgrG-related protein	NA	NA	NA	NA
WP_003951809.1|6262039_6262762_-	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_003951810.1|6262810_6263233_-|tail	phage tail protein	NA	NA	NA	NA
WP_159313410.1|6264950_6265409_+	hypothetical protein	NA	NA	NA	NA
WP_159313411.1|6266510_6266867_+	hypothetical protein	NA	NA	NA	NA
WP_003951815.1|6266979_6267480_-	hypothetical protein	NA	NA	NA	NA
WP_003951816.1|6267479_6267926_-|tail	phage tail protein	NA	NA	NA	NA
WP_159313412.1|6268000_6269596_-|tail	phage tail sheath family protein	J9PVC2	Bacillus_phage	1.8e-65	32.9
WP_015506831.1|6269968_6271309_+	hydrolytic protein	NA	NA	NA	NA
WP_030769340.1|6271342_6273400_-	ATP-binding protein	A0A0R6PCP6	Moraxella_phage	1.0e-20	31.0
WP_003951819.1|6273399_6274071_-	DUF4255 domain-containing protein	NA	NA	NA	NA
WP_008412680.1|6274230_6274839_-	response regulator transcription factor	NA	NA	NA	NA
WP_159313413.1|6275250_6278142_+	AAA family ATPase	NA	NA	NA	NA
WP_159313414.1|6278169_6278487_+	hypothetical protein	NA	NA	NA	NA
WP_159313415.1|6278479_6278959_-	diadenosine tetraphosphate hydrolase	NA	NA	NA	NA
WP_003951824.1|6278968_6279913_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_037841730.1|6280028_6280895_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_067416786.1|6280898_6281687_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_030305556.1|6281827_6282892_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_003951828.1|6282897_6283770_+	siderophore-interacting protein	NA	NA	NA	NA
WP_159313416.1|6283759_6284761_+	iron chelate uptake ABC transporter family permease subunit	NA	NA	NA	NA
WP_159313417.1|6284757_6285840_+	iron chelate uptake ABC transporter family permease subunit	NA	NA	NA	NA
WP_010641004.1|6285920_6286694_+	ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_159313418.1|6286778_6288575_+	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	1.1e-07	21.7
WP_159313419.1|6288571_6290332_+	ATP-binding cassette domain-containing protein	F2Y2R6	Organic_Lake_phycodnavirus	1.7e-08	26.1
WP_159313420.1|6290535_6293154_+	glycoside hydrolase family 2	NA	NA	NA	NA
WP_159313421.1|6293231_6295643_+	hypothetical protein	NA	NA	NA	NA
WP_159313422.1|6295728_6296553_+	isocitrate lyase/phosphoenolpyruvate mutase family protein	NA	NA	NA	NA
WP_159313423.1|6296570_6298511_-	ATP-binding cassette domain-containing protein	F2Y2R6	Organic_Lake_phycodnavirus	7.7e-15	29.1
WP_159313424.1|6298727_6300275_-	AMP-binding protein	A0A1V0SBX8	Catovirus	1.6e-15	24.9
WP_003951838.1|6300351_6300960_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_159313425.1|6301015_6302668_+	DNA alkylation response protein	NA	NA	NA	NA
WP_159313426.1|6302677_6303727_-	amidohydrolase family protein	NA	NA	NA	NA
WP_033238272.1|6303810_6304443_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_159313427.1|6304582_6306190_+	bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase	NA	NA	NA	NA
WP_159313428.1|6306203_6307079_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_159313429.1|6307075_6308095_+	extradiol ring-cleavage dioxygenase	NA	NA	NA	NA
WP_030769295.1|6308237_6309521_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_159313430.1|6309542_6310625_-	amidohydrolase family protein	NA	NA	NA	NA
WP_159313431.1|6310781_6311456_+	TetR family transcriptional regulator	NA	NA	NA	NA
WP_003951846.1|6311452_6312085_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_018469051.1|6312121_6312901_+	exodeoxyribonuclease III	NA	NA	NA	NA
WP_008415979.1|6312914_6314705_-	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_003951849.1|6315001_6315439_+	hypothetical protein	NA	NA	NA	NA
WP_003951850.1|6315598_6316342_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.3e-31	39.5
WP_127451644.1|6316354_6317293_+	glutamate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_030769285.1|6317307_6317952_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_015506817.1|6317948_6318821_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_159313432.1|6318872_6320468_-	CocE/NonD family hydrolase	NA	NA	NA	NA
WP_159313433.1|6321506_6322781_-	hypothetical protein	NA	NA	NA	NA
6323795:6323811	attL	NA	NA	NA	NA
WP_159313992.1|6324151_6325024_-	peptidoglycan DD-metalloendopeptidase family protein	V5R8R0	Arthrobacter_phage	1.3e-14	48.8
WP_107060924.1|6325622_6326381_-|transposase	transposase	NA	NA	NA	NA
WP_159313434.1|6326685_6327456_-|transposase	transposase	NA	NA	NA	NA
WP_159313435.1|6328457_6328859_+	hypothetical protein	NA	NA	NA	NA
WP_159313436.1|6328864_6329674_-|transposase	IS5 family transposase	NA	NA	NA	NA
WP_159313437.1|6329931_6330921_+|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_159313993.1|6330941_6332177_+	sensor histidine kinase	NA	NA	NA	NA
WP_159313438.1|6332173_6332848_+	response regulator	NA	NA	NA	NA
WP_159313439.1|6334746_6335652_-	NAD-dependent epimerase/dehydratase family protein	NA	NA	NA	NA
WP_159313440.1|6335693_6336560_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_159313441.1|6336634_6337105_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_159313442.1|6337996_6338323_-	hypothetical protein	NA	NA	NA	NA
WP_159313443.1|6338651_6339131_-	hypothetical protein	NA	NA	NA	NA
WP_159313444.1|6339238_6340105_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_159313445.1|6340713_6341760_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_121842937.1|6341756_6342107_-	hypothetical protein	NA	NA	NA	NA
WP_159313446.1|6342120_6342621_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_159313447.1|6343509_6344571_+|transposase	ISAzo13 family transposase	NA	NA	NA	NA
WP_159313448.1|6345025_6345943_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_159313449.1|6346073_6347315_+	MFS transporter	NA	NA	NA	NA
WP_159313450.1|6347561_6348230_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_159313451.1|6348328_6349837_+	DHA2 family efflux MFS transporter permease subunit	A0A0M3UL24	Mycobacterium_phage	5.7e-58	35.5
WP_159313452.1|6349917_6351129_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_159313453.1|6351702_6351966_+	hypothetical protein	NA	NA	NA	NA
WP_159313454.1|6352156_6353038_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_159313455.1|6353152_6354001_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_159313456.1|6354135_6355557_-	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_159313457.1|6356983_6357973_-	endoglucanase	NA	NA	NA	NA
WP_159313458.1|6358884_6359499_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_159313459.1|6359569_6360589_+	NAD-dependent epimerase/dehydratase family protein	NA	NA	NA	NA
WP_159313460.1|6360808_6361438_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_159313461.1|6361437_6362523_-	S-(hydroxymethyl)mycothiol dehydrogenase	A0A0K0KVL7	Prochlorococcus_phage	7.1e-34	29.5
WP_159313462.1|6362698_6363964_+	LuxR family transcriptional regulator	NA	NA	NA	NA
WP_159313463.1|6365095_6365356_-	hypothetical protein	NA	NA	NA	NA
WP_159313464.1|6367839_6368403_+	DUF4291 family protein	NA	NA	NA	NA
WP_159313465.1|6368515_6369325_-	SAM-dependent methyltransferase	NA	NA	NA	NA
WP_159313466.1|6369450_6371097_-	SpoIIE family protein phosphatase	NA	NA	NA	NA
WP_159313467.1|6376602_6377355_+	hypothetical protein	NA	NA	NA	NA
WP_159313468.1|6377375_6377966_+	hypothetical protein	NA	NA	NA	NA
WP_159313469.1|6378464_6379607_-	hypothetical protein	NA	NA	NA	NA
WP_159313470.1|6380117_6381590_-	hypothetical protein	NA	NA	NA	NA
WP_159313471.1|6381952_6382558_+	hypothetical protein	NA	NA	NA	NA
WP_159313472.1|6382554_6385008_-|integrase	site-specific integrase	NA	NA	NA	NA
WP_159313473.1|6385004_6385358_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_159313474.1|6385377_6386481_-|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
6394424:6394440	attR	NA	NA	NA	NA