CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP047421	Shewanella algae strain 18064-CSB-B-B plasmid p18064-65-CSB-B-B, complete sequence	0 crisprs	DEDDh	0	0	1	0
NZ_CP047422	Shewanella algae strain 18064-CSB-B-B chromosome, complete genome	4 crisprs	cas3,DEDDh,csa3,RT,DinG,WYL	0	0	8	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

57499 : 75618

Salmonella_phage(33.33%)

transposase,integrase

attL 50436:50450|attR 68587:68601

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
50436:50450	attL	NA	NA	NA	NA
WP_000427619.1\|57499_58504_-\|transposase	IS110-like element IS5075 family transposase	NA	NA	NA	NA
WP_001138073.1\|58582_61555_-\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	0.0e+00	73.1
WP_001162012.1\|61557_62115_-	recombinase family protein	A0A1B0V7I5	Salmonella_phage	5.8e-48	81.3
WP_000845048.1\|62420_63434_-\|integrase	class 1 integron integrase IntI1	A0A1P8DJJ6	Virus_Rctr41k	1.0e-71	45.5
WP_001083725.1\|63578_64076_+	trimethoprim-resistant dihydrofolate reductase DfrA12	A0A0A0PL85	Bacillus_phage	7.5e-23	40.9
WP_001336345.1\|64187_64478_+	DUF1010 domain-containing protein	NA	NA	NA	NA
WP_000679427.1\|64582_64930_+	quaternary ammonium compound efflux SMR transporter QacE delta 1	NA	NA	NA	NA
WP_000259031.1\|64923_65763_+	sulfonamide-resistant dihydropteroate synthase Sul1	A0A0B5J4J5	Pandoravirus	5.0e-11	27.2
WP_000050481.1\|66167_67709_+\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_000359986.1\|69107_69881_+	ArmA family 16S rRNA (guanine(1405)-N(7))-methyltransferase	NA	NA	NA	NA
68587:68601	attR	NA	NA	NA	NA
WP_077252464.1\|69861_70143_-	hypothetical protein	NA	NA	NA	NA
WP_002026779.1\|70362_70548_-	hypothetical protein	NA	NA	NA	NA
WP_001067858.1\|70941_71646_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.2e-138	99.6
WP_000429836.1\|74100_74535_+	Hg(II)-responsive transcriptional regulator	NA	NA	NA	NA
WP_000427623.1\|74613_75618_+\|transposase	IS110-like element IS4321 family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP047422

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP047422_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047422_1

320143-320236

Orphan

Consensus_repeat	Method
TTTGTTCCAGACAAATTCGGCAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP047422_1

>merge|NZ_CP047422|1|320143-320236|CRISPRCasFinder
TTTGTTCCAGACAAATTCGGCATTTCCTACGTCCCTGTAGGTCAGATGTTTTCGTCGAGGCTACCACCGCATTTGTTCCAGACAAATGTCGGCA

>NZ_CP047422|1|1|320143-320236|CRISPRCasFinder
TTTGTTCCAGACAAATTCGGCAT	TTCCTACGTCCCTGTAGGTCAGATGTTTTCGTCGAGGCTACCACCGCA
TTTGTTCCAGACAAATGTCGGCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047422.1\|WP_159352339.1\|311220_312366_-\|DUF5009-domain-containing-protein	unknown	unknown	gnl\|CDD\|226749
NZ_CP047422.1\|WP_028779000.1\|325386_326676_-\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224172
NZ_CP047422.1\|WP_062794005.1\|326813_328172_-\|MATE-family-efflux-transporter	unknown	unknown	gnl\|CDD\|240548
NZ_CP047422.1\|WP_159352338.1\|308109_308877_+\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|238923
NZ_CP047422.1\|WP_159352341.1\|313653_314652_-\|SIS-domain-containing-protein	unknown	unknown	gnl\|CDD\|225132
NZ_CP047422.1\|WP_071237992.1\|306821_307370_-\|cytochrome-b	unknown	unknown	gnl\|CDD\|225580
NZ_CP047422.1\|WP_101055434.1\|336157_337426_-\|glucose-1-phosphate-adenylyltransferase	unknown	unknown	gnl\|CDD\|234824
NZ_CP047422.1\|WP_159352342.1\|328348_329482_-\|GTP-binding-protein	unknown	unknown	gnl\|CDD\|349766
NZ_CP047422.1\|WP_159353321.1\|334505_336128_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|340822
NZ_CP047422.1\|WP_025011427.1\|324306_325323_+\|LacI-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380487
NZ_CP047422.1\|WP_117200427.1\|315957_318654_-\|family-20-glycosylhydrolase	unknown	unknown	gnl\|CDD\|119337
NZ_CP047422.1\|WP_045282933.1\|321189_323823_-\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|273804
NZ_CP047422.1\|WP_045282939.1\|306241_306817_-\|YceI-family-protein	unknown	unknown	gnl\|CDD\|179642
NZ_CP047422.1\|WP_117200428.1\|314648_315596_-\|ATPase	unknown	unknown	gnl\|CDD\|225518
NZ_CP047422.1\|WP_144167539.1\|331378_334432_-\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|182070
NZ_CP047422.1\|WP_025009486.1\|319278_319965_+\|SapC-family-protein	unknown	unknown	gnl\|CDD\|377801
NZ_CP047422.1\|WP_159352343.1\|330056_331325_-\|DEAD/DEAH-box-helicase	unknown	unknown	gnl\|CDD\|223587
NZ_CP047422.1\|WP_159352340.1\|312458_313604_-\|N-acetylglucosamine-6-phosphate-deacetylase	unknown	unknown	gnl\|CDD\|224733
NZ_CP047422.1\|WP_071475617.1\|309419_310736_-\|sugar-MFS-transporter	unknown	unknown	gnl\|CDD\|340952
NZ_CP047422.1\|WP_101059093.1\|329610_329880_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP047422.1\|WP_159352339.1\|311220_312366_-\|DUF5009-domain-containing-protein	gnl\|CDD\|226749	COG4299, COG4299, Uncharacterized protein conserved in bacteria [Function unknown].	6.07397e-46
NZ_CP047422.1\|WP_028779000.1\|325386_326676_-\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224172	COG1252, Ndh, NADH dehydrogenase, FAD-containing subunit [Energy production and conversion].	5.16428e-125
NZ_CP047422.1\|WP_062794005.1\|326813_328172_-\|MATE-family-efflux-transporter	gnl\|CDD\|240548	cd13143, MATE_MepA_like, Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Streptococcus aureus MepA and Vibrio vulnificus VmrA and functions most likely as a multidrug efflux pump.	3.12072e-114
NZ_CP047422.1\|WP_159352338.1\|308109_308877_+\|EAL-domain-containing-protein	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	9.96077e-57
NZ_CP047422.1\|WP_159352341.1\|313653_314652_-\|SIS-domain-containing-protein	gnl\|CDD\|225132	COG2222, AgaS, Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane].	1.42835e-80
NZ_CP047422.1\|WP_071237992.1\|306821_307370_-\|cytochrome-b	gnl\|CDD\|225580	COG3038, CybB, Cytochrome B561 [Energy production and conversion].	3.5605e-60
NZ_CP047422.1\|WP_101055434.1\|336157_337426_-\|glucose-1-phosphate-adenylyltransferase	gnl\|CDD\|234824	PRK00725, glgC, glucose-1-phosphate adenylyltransferase; Provisional.	0
NZ_CP047422.1\|WP_159352342.1\|328348_329482_-\|GTP-binding-protein	gnl\|CDD\|349766	cd03112, CobW-like, cobalamin synthesis protein CobW. The function of this protein family is unknown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterize it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage caused by mitomycin. YijA gene is a homologue of the CobW gene which encodes the cobalamin synthesis protein/P47K.	6.0821e-50
NZ_CP047422.1\|WP_159353321.1\|334505_336128_-\|glycosyltransferase	gnl\|CDD\|340822	cd03791, GT5_Glycogen_synthase_DULL1-like, Glycogen synthase GlgA and similar proteins. This family is most closely related to the GT5 family of glycosyltransferases. Glycogen synthase (EC:2.4.1.21) catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family includes starch synthases of plants, such as DULL1 in Zea mays and glycogen synthases of various organisms.	6.40742e-104
NZ_CP047422.1\|WP_025011427.1\|324306_325323_+\|LacI-family-transcriptional-regulator	gnl\|CDD\|380487	cd01545, PBP1_SalR, ligand-binding domain of DNA transcription repressor SalR, a member of the LacI-GalR family of bacterial transcription regulators. Ligand-binding domain of DNA transcription repressor SalR, a member of the LacI-GalR family of bacterial transcription regulators. The SalR binds to glucose based compound Salicin which is chemically related to aspirin. The ligand-binding of SalR is structurally homologous to the periplasmic sugar-binding domain of ABC-transporters and both domains contain the type 1 periplasmic binding protein-like fold. The LacI-GalR family repressors are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the type 1 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding affinity of the repressor.	1.18355e-116
NZ_CP047422.1\|WP_117200427.1\|315957_318654_-\|family-20-glycosylhydrolase	gnl\|CDD\|119337	cd06569, GH20_Sm-chitobiase-like, The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin. Chitin is degraded by a two step process: i) a chitinase hydrolyzes the chitin to oligosaccharides and disaccharides such as di-N-acetyl-D-glucosamine and chitobiose, ii) chitobiase then further degrades these oligomers into monomers. The GH20 hexosaminidases are thought to act via a catalytic mechanism in which the catalytic nucleophile is not provided by solvent or the enzyme, but by the substrate itself.	0
NZ_CP047422.1\|WP_045282933.1\|321189_323823_-\|TonB-dependent-receptor	gnl\|CDD\|273804	TIGR01782, TonB-dependent_receptor, TonB-dependent receptor. This model represents a family of TonB-dependent outer-membrane receptors which are found mainly in Xanthomonas and Caulobacter. These appear to represent the expansion of a paralogous family in that the 22 X. axonopodis (21 in X. campestris) and 18 C. crescentus sequences are more closely related to each other than any of the many TonB-dependent receptors found in other species. In fact, the Crescentus and Xanthomonas sequences are inseparable on a phylogenetic tree using a PAM-weighted neighbor-joining method, indicating that one of the two genuses may have acquired this set of receptors from the other. The mechanism by which this family is shared between Xanthomonas, a gamma proteobacterial plant pathogen and Caulobacter, an alpha proteobacterial aquatic organism is unclear. [Transport and binding proteins, Porins].	0
NZ_CP047422.1\|WP_045282939.1\|306241_306817_-\|YceI-family-protein	gnl\|CDD\|179642	PRK03757, PRK03757, YceI family protein.	1.13269e-126
NZ_CP047422.1\|WP_117200428.1\|314648_315596_-\|ATPase	gnl\|CDD\|225518	COG2971, COG2971, Predicted N-acetylglucosamine kinase [Carbohydrate transport and metabolism].	3.12594e-59
NZ_CP047422.1\|WP_144167539.1\|331378_334432_-\|EAL-domain-containing-protein	gnl\|CDD\|182070	PRK09776, PRK09776, putative diguanylate cyclase; Provisional.	3.45255e-130
NZ_CP047422.1\|WP_025009486.1\|319278_319965_+\|SapC-family-protein	gnl\|CDD\|377801	pfam07277, SapC, SapC. This family contains a number of bacterial SapC proteins approximately 250 residues long. In Campylobacter fetus, SapC forms part of a paracrystalline surface layer (S-layer) that confers serum resistance.	1.89098e-85
NZ_CP047422.1\|WP_159352343.1\|330056_331325_-\|DEAD/DEAH-box-helicase	gnl\|CDD\|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	2.82832e-145
NZ_CP047422.1\|WP_159352340.1\|312458_313604_-\|N-acetylglucosamine-6-phosphate-deacetylase	gnl\|CDD\|224733	COG1820, NagA, N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism].	3.79845e-145
NZ_CP047422.1\|WP_071475617.1\|309419_310736_-\|sugar-MFS-transporter	gnl\|CDD\|340952	cd17394, MFS_FucP_like, Fucose permease and similar proteins of the Major Facilitator Superfamily of transporters. This subfamily is composed of L-fucose permease (also called L-fucose-proton symporter) and similar proteins such as glucose/galactose transporter and N-acetyl glucosamine transporter NagP. L-fucose permease facilitates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell; it can also transport L-galactose and D-arabinose. Glucose/galactose transporter functions in the uptake of of glucose and galactose. The FucP-like subfamily belongs to the bacterial fucose permease, eukaryotic Major facilitator superfamily domain-containing protein 4 (FucP/MFSD4) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.67736e-105

>NZ_CP047422.1|WP_025009486.1|319278_319965_+|SapC-family-protein
MTAQYVPLNNGAHKALKVTPGIDFSEFEKHHMLPLLVQEFLPAATSFPIIFAKNSQSGEFQPVAITSLKPESNCFIKDNTWTRRYLPMQCRMQPFAAGDSSQENVLIGIDVNSKHVSEDKGEALFTETGEQTEFLKNRIEFIGNLIEYREITKQFVKTLTSHELLQPKTLTVTNKQGEKSNIDGLYIVDEQKLNALSDEVKLEFAKRGVYSPVYAHLCSLNQIDLLLD
>NZ_CP047422.1|WP_117200427.1|315957_318654_-|family-20-glycosylhydrolase
MKLTIAALAIALSLGLTACSDKPPATGTEPGQAGSSSKASNEDLTQNKLHSFAQSLQLKYAVLSNVPDDNCDPSRAEGRCFQAQIRLTPSEDLSASDWAIYFSQMRPVLSVASPEFHIEHIQGDLHRLTPTAAFGGFKKGVSEIINFRGELWQLSEIDAMPNYYMVVEGLKPEIIASTEVKQDPDTGLELLPYVQPYTDAEKQYRRSSQDRLPWDTANAVFGQNADTPDDAGLAAASLIPKPDSVTWLEQTPVTLNAGIKLNPSHIANGVDLQSLEAALLRLQRLGVSQSEQGLALNLLPLEGGQSEHYRLEIEVGGINLAAADAAGYSYGLASLAALLQLPADDTQSIALPQLRIQDSPRYSFRGMHLDVGRNFHSKAFVLSLLEQMAAYKLNVLHLHMADDEGWRLQIPGLPELTEIGSKRCHDLDENRCLLPQLGSGPNPETQVNGYYTTQDYIDILKFAAARQIQVIPSMDMPGHSRAAIKSMQARSRKLLAQGDSQAASQYLLADPEDATVYSSIQYYNDNTLNVCMESSYTFVAKVIDEIAKLHQAAGVPLKRYHIGADETAGAWLDSPACERFIAANSQRVADKSALGAYFIERVSQMLAERGIEAAGWSDGMSHVNPANMPSPVQSNIWDIVAHGGFKRAHAQANLGWDTVLSNPEVLYFDMPPAADPKEPGYYWASRSSNSRKLHSFMPDNLPANAEQWGDIEARPFIADDTEQLSPQGKRLSGPMAPGRGFIGLQGQLWSETIRSDTTAAYMIFPRLLVLAEKAWHKPDWELAYRHQGASYSQDSGYFVAEQRQAQAEDWHRLANILGHKELAKLDKAGVHYRLPLPGGRIKDGKLEANIIFPGLKIQYRRPGAEWQEYRGPVAIAAPLELRTVSPDGRRYSRVQPLN
>NZ_CP047422.1|WP_117200428.1|314648_315596_-|ATPase
MGENPTPDTQVYIGIDGGGSKCRATVYCWQKGVLGTGVAGRANPLHGLSQTFDSIISATGLALADAGLRQADCANMVAGLGLAGVNIPRLYQEILDWRHPFAAMYLTTDLHTACIGAHQGDDGAVIITGTGSCGYAHVGERQLSLGGHGFALGDKGSGAWMGLKAAEQVLLSLDGFAPQTALGAKLLAHFGVTDALGIVENLAGRSSSCYAALARIVLSCAAEGDDTATAIVSEGADYISRLARRLFELNPPRFAMIGGLAEPLRPWLADDVVERIAPVLASPEIGAVHFAMHQHSQFSARPADAGAYDLAKVKP
>NZ_CP047422.1|WP_159352341.1|313653_314652_-|SIS-domain-containing-protein
MTHTIMEREARSAPEKIANQLQANDRLARELGQRLREFAPKFVMIVGRGSSDHAGVFAKYLFEIEAGVPTFAAAPSVASVYGKRLQLAGGLVIVISQSGRSPDILAQAKMAREAGAFCVALVNDETAPIKDIVDLVLPLRAGEEQAVAATKSYLATLSALLQLAAAWTQSPELARAIDELPQALQAAVDAEPQLTAESLQHSNNLVVLGRGLGYAISKEIALKLKEVCAIHAEAFSSAEFLHGPVTLVENHLKIVDVCVADESYASHLEQIAEVGRRGAELVHLKQTANEVHPRVAPLALLQRFYIDVAAVAIARGIDPDQPAGLKKVTQTL
>NZ_CP047422.1|WP_159352340.1|312458_313604_-|N-acetylglucosamine-6-phosphate-deacetylase
MTQTFIAERLFDGRQYHHNLSFAVENGNLQALGSAAASDAIRLQGLVVPGFIDVQVNGGGGALFNGEPTLECIATIGRAHARFGTTGFLPTLITDRIEVMNRAADAVAEAIARQSTGVLGIHFEGPHLSVPKKGVHLQQYIRRISDAELALFSRQDLGVRLVTLAPENVAPEVIRALVEAGVRVCLGHSNADYDTVRSALAAGASGFTHLYNAMSPLGSRAPGMVGAAIEDEASWCGLIVDGHHVHPAAAKVAIRAKAKGKMLLVTDAMPPMGLDQDASFELFGQQVLRQGDRLNAITGELAGCVLDMNTAVRNAVSLLGLSVEESMRMASEYPAAFLGLEQQGHLAAGKRADFLVLDNELKVQNTYIGGQLVYAAEERVC
>NZ_CP047422.1|WP_159352339.1|311220_312366_-|DUF5009-domain-containing-protein
MTEKIAAVTETANKPRLMSLDALRGFDMFWILGGEALFAALLLLTTWSGWRWFDGQMHHSSWHGFTFYDLIFPLFIFLSGVALGLSPKRLDKLALAERLPKYKHAVKRLALLLFFGVLYNHGWGTGMPAALDEIRYASVLGRIAFAWFFAAMLVWHTGLRTQIYVAVAILLGYAMVQLWLPVPGGSAGDFSAAGSINAWVDSHFLPGISYQHKPYDPEGLLSTLPAVVNALAGVFVGRFLQQQSFSAWGRVGLLCLAGLVCLGLGWLLNPLIPVNKDLWTSSFVLVSSGWSLLLLVLFYAVIDVLGLRWLGFPFVVIGCNAIIIYLASSLVQWRYSSESLLGGFINSAPENWQPLLGVLAMLGVQWLLLWWMYRRQLFIRV
>NZ_CP047422.1|WP_071475617.1|309419_310736_-|sugar-MFS-transporter
MTVATPADAASRSSFLPMTIVGALFFIFGFVTWLNGSLIPFLQIICELNEFQALFVTFAFYIAYTVMALPMSSILRRTGYRNGMAVGLGIMAVGSVLFIPAAFSANFLMFLLALFVLGTGLTILQTASNPYVVHIGPKESAAMRISIMGLINKGAGVIVPILFTALVLADLEGFTAGHLAAMAPAEREAQISELSARLVMPYIYMTLALVVLIALVKFSALPEIAFEGEEGEHADKSGIVHFPQVILGAIAIFAYVGVEVIAGDTIGLYGASLGVNNFASLTSYTMVFMVIGYLLGVSCIPRFISQEKALLASALAGIACIFGIIFSSAESHAISSLLWGWSGIPTIPDTVTFVAMMGLAHALVWPSVWPLALEGLGKYTAQGSALLIMGISGGAILPLIFGKIAHFSDNVQLGYWIGLPCYLFILFYALKGHKMRSW
>NZ_CP047422.1|WP_159352338.1|308109_308877_+|EAL-domain-containing-protein
MLEGTASYEIHSCSNCLNKKELGFDFSMAFQPIINIKNNSVFGYEALVRGLNNEAVGQIFSKVNDHNRYIFDQMCRIKAISLASRLGIDSMLSINFLPNAVYKPERCIRTTLEAAKKYNFPTERIMFEFTEVEKIEDSNHVKRIVECYRALGFITAIDDFGSGYSGLDLLANFQTNIIKLDMALIRNIDTDKVRQSIVTHCLSMFQDLGIIPLAEGIETQGECFWLKTAGIELMQGYLFAHPGFESLPRIDFSNL
>NZ_CP047422.1|WP_071237992.1|306821_307370_-|cytochrome-b
MLANTRQGYGLVSILSHWLSAIAVIGLFGLGYWMVDLTYYSAWYQKGPHLHKSIGILLLALTLVRLLWKLLSPSPQAIPDKPLLQKAARLTHWGLYLLLLLIMLSGILISTADGRGIAVFDWFELPGVGELFNNQADIAGAIHKYAAYSLIALVVLHALAALKHHFIDKDQTLVRMIKLKRG
>NZ_CP047422.1|WP_045282939.1|306241_306817_-|YceI-family-protein
MKKTLFAGLLGSALLLPCAVNADDYVIDTQGAHASINFRVNHLGYSFVVGRFNEFEGSFSFDKANPADAKVNVTINTQSLDSNHAERDKHLRSADFINAGKYPKASFKSTKVEDKGNGELAITGDFTLNGVTKPLTIDAKAIGEGQDPWGGYRAGFVGSTEFALKDYKITTDLGPASTHVKLDLVVEGVKQ
>NZ_CP047422.1|WP_045282933.1|321189_323823_-|TonB-dependent-receptor
MRTSTFKKTALAANIAILLGGAVSVGALAAEAADNNSNETANIEKIEVRGMRASMKASVNTKRFSDAVVDAVTSEDIGKFPDSDVGESLGRIPGVAVNRQFGQGQQVSIRGASAQLTSTQLNGHSVASTGWFDQQAIDRSFNYTLLPPEMVGSIEVYKSSQADIAEGGIGGTVIINTRKPLDLDANSVFLSAKGDYGSVSEEIDPEASGLYSWKNEDENFGVLLAGSWSQTDYQRNGIETLLGWGEIVPTTFQQDRERTAINLVLQYRPTDRLELGLNYMNLELDANNANTSIFLFPTQRGDYTCEQVNAAGVCTKINHSDQGGFAWAQTWARKASMSSDTVDFNFNYEADNFTVEGRIGRTEAEGGTDLTANYGNSIGVPADFAGIYDATGDKINIDIANKYFEASDFNDPLATAGWALKKQPNTDEETFAQLDFNFPVAWGAISAIKTGVSYADHEVTQMTDAAIVNDAKVLTKDASAYYNGTMSSGAGFTLPEPIFDAMIADAYAAIDGFTVDKSGYGTIQEENLALYAMATFAGEGFRGNFGFRYISTDIESDYYALNDQGQFADDLSTDKSSYNDVLPSVNIAFDLSEDVILRASAAQVISRPNYAELFATSTLPGYNDGTPFNEKLVRGSVALEPFKATQADLSLEWYFSDSGLFAATYFIKDVSSFITTKQKLNQQIGIEDPNLVTEGESSCGVGIYDCWTVSEKYNADGGSIDGIELQLQDSFDNGLGYSVNYTFADASSPAENYPDRVGVFSDSSKHTVNLVGYYEMDDFSARLAYNWRSEYMMRELPGFYGNRQHESYGTLDLSASYSVTDYLDITFEAVNITEEDSIQTGVSPISAEDVISEFKADYPVWSFEGEARYKVGVALRF
>NZ_CP047422.1|WP_025011427.1|324306_325323_+|LacI-family-transcriptional-regulator
MKVTINDVAKYAGVSIKTVSRVTNNEPSVKQATIDKVNAAIKALNYQPNLAARNLAATSSYVIGFVYDNPNAYYIIDMQNGILSACRDKGYELLIHPCDAKADGICEQLTTMVKHARLAGLVLTPPLSEDPKVLSALDAIGANYVRIMAGDRVKADTGLAVLVNDRSGAVAITQHLIDLGHRQIAFLSGDYHHQSTKERLEGYRQALRDNDLDESPELIVEGEYSFESGVEGAKKLLKGANRPSAIVACNDEIAAGALFAARLEGVDIPTELSIVGFEDSPFSRQTWPKLTTVHQPNGKIAQIATELLIANRREQSARAEIFTPEPVIRDSSARVQAS
>NZ_CP047422.1|WP_028779000.1|325386_326676_-|NAD(P)/FAD-dependent-oxidoreductase
MTGKRILIVGGGAGGLALASKLGRKLGLKEEAEITLIDKSPVHIWKPKLHEVAVGVIDQSVEGLLYRDHGLKNGYRFLRGEMLQCDPEAKTITLAGVSNDDGEQIIAERELPYDYLVVAIGGVANSFNTPGAKEHCIFLDSLDSANQFHHKLLDNLLLLDETSEKLSIGIVGAGATGVELAAELHHVLDSVKEYGYLNVDKHHLEIHLIEAAPKILPALPDKVSSRAQSVLDHIGVRLHIGVQVKEVTKQGFITQEDVLIPAGLKVWAAGVKGPDVLQQFDKLPVNNRNLIEVDACMRVKGHKDIYALGDCAFLVQDNGKPVPPRAQAASQMAETLYKNILNRLKGKAENPFVYRDYGSLVSLSRFSAVGNLMGNLRSGSLFIEGYVARMMYMSLYQRHLASLYGWFSALVYRLAQRLLKWHRPKLKLH
>NZ_CP047422.1|WP_062794005.1|326813_328172_-|MATE-family-efflux-transporter
MTPNSPQTEQDLALLQQPVSKLFWRYTVPTVMSMLVTGIYVTIDGMFIGHYLGETGLAGIMLAYPVGAILYALGALLGMGGAALISINLGRGDVARARKILGNTFSLCLLSALVVSLAGTMLTDDILRWLKAEGEVYEGAYQYLFWYFALGIFPIISMAFSALLRNDGRPSFVTWILVFGGVLNTLLDWLFIVVFPFGLAGAAIATMLSQAVTGGLCLQHFFGKRTRLNIDWQQMKLSLELVWEIVKLGMPSFLMNLYLSIVLTMHNMALLWTGTSLHVAAYGVVSYTEALFYFVFEGIALGTQPILSFNAGAGRYDRVKQTAKMAFSVTLICALLGLVLIYSRPEWMVYLFAGDNPTLAPVAIEGMYLYFWGLPMEGLILVGASFFQAINRPAEASILTGSKLLLIGLFLWVFAWAFGVPGVWISLASCSSLLCLWMFYSLKRTKVALHQP
>NZ_CP047422.1|WP_159352342.1|328348_329482_-|GTP-binding-protein
MILKPVATNLITGFLGSGKTTFIKALLANKPAGETWAVLVNEFGEIGIDAGLMGQSDSGVVIREVPGGCLCCAAGVPTQVAVTQLLARAKPDRLLIEPTGLGHPKEILKTLSSKQFAEVLSLKASICLFDPRKLSDKRYTEHENFLSQLQIADILLAGKQDLWQQQEPMVLPGGGPQSAKGNEPQSDQESKRLAAHLRKQIAAFIAAQQLEGELFYWSKEQKLNDELLRALARPAKANLNTKATPLGAGLLRQNAGVFAIKPLDAEPQSSETPEWDARGIVFKSNKGEGCYSYGWIFTPDWLFDLERLYRWAKALDVVRLKAVMITKDGIAALNMLDGELSVEELDDAMDSRLEIISRAPLQPESLEQQLLAIKVAE
>NZ_CP047422.1|WP_101059093.1|329610_329880_-|hypothetical-protein
MSSTEIASWKEAGFDSRSAQQWHVAGFDASSAGAWQDAGFKLQDAKEWHLQSFSAAEAKGWRAGGFDLDDAMKNRAKGLTPIVDHELKP
>NZ_CP047422.1|WP_159352343.1|330056_331325_-|DEAD/DEAH-box-helicase
MQFSETQLPGPLLEAVAQCGYRELTAVQQQVLPAALAGRDIMASAQTGTGKTAAFGLPLLAALIDEWQQQGLAEPEYGAAPRVLILTPTRELAQQVATQLGKYAAHTPFRILAIFGGANFNPQRKAIAAGIEVLVATPGRLFDHLSQDHLRLDKVKALVLDEADRMLDLGFLPDIERLGRYLPDGHQTMLFSATFPEAVKRLGHKLLDKPEWFEVDKESRTQAQIQQKVYPVDYRRKAELLAELIGRNNWQQVLAFVSTKESAEQLQQELKLDGIKSACFHGDKTQGARSRALAQFIDGEVRVLVATDVAARGLDIPALPRVINLELPSQADDYIHRIGRTGRAGRSGEAISLVSPAEEQKLVEIEALLGYKLPREVLPGYEKGAPLPERYLQSIEKPRPAKTHRGHKPGRKGQAPKGPRRR
>NZ_CP047422.1|WP_144167539.1|331378_334432_-|EAL-domain-containing-protein
MEQSIFLPLAQNAAFLLALVFMYDAIPRQQQREYFLLWRLLIGVIIGGICIAVMLTPWSYEPGIFFDSRSVLLSISGLFFGGLPTIIACVITAAFRIYLGGGAVWIGVGVIFSSGLIGLLWRKRRKQSLADIGYPELAGFSLLVHLVMLAWMLLLPWETAKGVLASISLPLLTLFPLTNVLLGRLLSRRLEFERDNRIRLQDDFLFRSQFHVGNIGISITSPDQRWLKINPHMCRMLGYTEQELSQLTWSELTHPDDLPADMAQFRRMLDGEIDEYEMEKRFVSKQGQYVYTHMTVACQRHHQQVQLVIAGYIDITSAKLAEQAIAASRDQLELVLQSGQLGFWDWDPVKDTVVRNKRSAEILGCSLNNLNDNKRLWLDGIHPKDRAWVLRSLDEHLAGKTEQHKVQYRLIRPDGELRWVQDTGKVVSRDEKGRPLRVCGVHVDITEQKQLEASLKLAASVYENSSEAMSVLDDVGTIMTVNSAFSAITGYQPQDVLGSNIDMLKCDDHDERFYRELNHDLSHKGRWQGEMWLRCSDGRKIMIWLSINTIHSTDDTPLRRVALFSDITDKKQNERLIWRQANYDALTGLPNRRMFTEHLGNEIRKAKRHGHGFALLFLDLDFFKEVNDTLGHDMGDLLLVETSERLQACVRESDVVARLGGDEFTLLLSDVQDHNGVERVANHILSSLAEPFKLGDETAFISASIGITLYPDDGQTVELLLKHADQAMYAAKDQGRNRFNYFTASMQEYARYRMRLIQDLRQALERREFELRFQPIVELGSGKVFKAEALLRWNHSERGSVSPAEFIPVAEDTGLIFEIGNWVFEQAARQSAAWREAYGSEVQISINKSPIQFRDEGNRFAEWLELLTSLGVSGSGICIEITEGLLLDANMGVTEKLLAYRDAGIQVSLDDFGTGYSSLAYLKRFDIDYLKIDQSFTRNLETDESDLTLCEAIIVMAHKLGMKVIAEGVETAGQAEILTRIGCDYAQGYLYSQALDIEGFEQKYLGKHQVIGGGNAS
>NZ_CP047422.1|WP_159353321.1|334505_336128_-|glycosyltransferase
MLAAENAALAGAKVGGMADVLAELPPALQSQGVAAHIIMPDYGFLAREQGADFLCQFEFAFGANTTRARLYRIANPAVQPGPQGLWIYLLAHEGFCSVKREVYSLDGPERPFATDAGKFALFGAAVAAALKQELLPLPDRFHLHDWHCGGFAMLRALDPAYRGLSKVPCILSIHNLAMQGVRPLAGEASSLAAWYPWLLAEGGNPKLQLALDTRYPGCINPLRAAIQFSDVIHLVSATYAKEVLCLSQPELGFFGGEGLEADLQDKAKLGQLFGILNGCDYQKGLPLATGKRQQLKLQLPKIATEALLSKLGRSDAVTPADMIAQIRLGQISESPGMLLTSVGRLTEQKLLLLCHPWQGKTVLEELLLRLAQFSDSACFWLLGSGDEQIAALFGRIAASNSNFRFINGYHQELADALYQCGDLFVMPSSFEPCGISQMLALRAGQPCLVHATGGLADTISDGDNGLVFAGTGLDEQAKALLDALSRALELYSTANWNALRKRASASRFSWQDSARLYMTQLYQVESCSKDERRLVESAIN
>NZ_CP047422.1|WP_101055434.1|336157_337426_-|glucose-1-phosphate-adenylyltransferase
MPNPSPRYISNLTRETYALILAGGRGSRLHELTDWRAKPALYFGGKFRIIDFPLSNCINSGIRRVGVVTQYKSHSLIRHVTRGWGHFKKELGESVEILPASQRYSDNWYQGTADAVFQNIDIIRHELPRYVMVLSGDHIYRMDYAGLLAAHAESGADMTVSCMEVPVAEAANAFGVMEVDSSNRILGFEEKPAQPRPLPDNPESCLASMGNYVFNTEFLFEQLKKDAQNADSNRDFGKDIIPAIIEKHRVYAYPFRSAFPNEQAYWRDVGTLDSFWQANMELLSPTPALNLYDAKWPIWTYQEQLPPAKFVFDDDDRRGMALDSVVSSGCIISGATVRHCVLFNEVRVCSYSEVEDSVILPDVVVLRHCRIRKAIIDRGCIIPEGMEIGFNHDHDRAKGFRVSESGVVLVTRDMLGLPVGYE

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Crispr_ID: NZ_CP047422_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047422_2

2895592-2895694

Orphan

Consensus_repeat	Method
ATTACCAAGAATAACAAAGACACC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP047422_2

>merge|NZ_CP047422|2|2895592-2895694|CRISPRCasFinder
ATTACCAAGAATAACAAAGACACCTACCAAGAATAACAAAGACACCCATTATTAACTGAGTGAAGACTCTAGTTGCCTGGATTACAAGAATAACAAAGACACC

>NZ_CP047422|2|2|2895592-2895694|CRISPRCasFinder
ATTACCAAGAATAACAAAGACACC	TACCAAGAATAACAAAGACACCCATTATTAACTGAGTGAAGACTCTAGTTGCCTG
GATTACAAGAATAACAAAGACACC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047422.1\|WP_159352920.1\|2902955_2903801_+\|peptide-chain-release-factor-N(5)-glutamine-methyltransferase	unknown	unknown	gnl\|CDD\|236467
NZ_CP047422.1\|WP_159352916.1\|2890654_2891629_-\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|223157
NZ_CP047422.1\|WP_045283891.1\|2884890_2885214_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047422.1\|WP_025011691.1\|2901858_2902944_+\|peptide-chain-release-factor-1	unknown	unknown	gnl\|CDD\|234801
NZ_CP047422.1\|WP_071237171.1\|2889691_2890105_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047422.1\|WP_025011687.1\|2887500_2888592_+\|redox-regulated-ATPase-YchF	unknown	unknown	gnl\|CDD\|236583
NZ_CP047422.1\|WP_025889918.1\|2903957_2904353_+\|SirB2-family-protein	unknown	unknown	gnl\|CDD\|377264
NZ_CP047422.1\|WP_028779724.1\|2905253_2906495_+\|DUF819-family-protein	unknown	unknown	gnl\|CDD\|114410
NZ_CP047422.1\|WP_025011684.1\|2883368_2884793_-\|tRNA-(N6-isopentenyl-adenosine(37)-C2)-methylthiotransferase-MiaB	unknown	unknown	gnl\|CDD\|237673
NZ_CP047422.1\|WP_159352919.1\|2900593_2901844_+\|glutamyl-tRNA-reductase	unknown	unknown	gnl\|CDD\|234592
NZ_CP047422.1\|WP_159352917.1\|2896219_2897194_-\|transposase	unknown	unknown	unknown
NZ_CP047422.1\|WP_144167843.1\|2885366_2886635_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|181564
NZ_CP047422.1\|WP_028779717.1\|2897781_2898729_-\|ribose-phosphate-pyrophosphokinase	unknown	unknown	gnl\|CDD\|234929
NZ_CP047422.1\|WP_144216078.1\|2892962_2893493_-\|DUF1768-domain-containing-protein	unknown	unknown	gnl\|CDD\|378035
NZ_CP047422.1\|WP_109248761.1\|2898808_2899687_-\|4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol-kinase	unknown	unknown	gnl\|CDD\|234731
NZ_CP047422.1\|WP_025011686.1\|2886827_2887415_+\|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl\|CDD\|235457
NZ_CP047422.1\|WP_159352918.1\|2899683_2900355_-\|outer-membrane-lipoprotein-LolB	unknown	unknown	gnl\|CDD\|377063
NZ_CP047422.1\|WP_071238787.1\|2891766_2892684_-\|IS5-family-transposase	unknown	unknown	gnl\|CDD\|290455
NZ_CP047422.1\|WP_109248065.1\|2890101_2890560_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047422.1\|WP_096140857.1\|2904352_2905144_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|225464

Protein	Function_ID	Function_description	E-value
NZ_CP047422.1\|WP_159352916.1\|2890654_2891629_-\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|223157	COG0079, HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase [Amino acid transport and metabolism].	3.03832e-66
NZ_CP047422.1\|WP_025011691.1\|2901858_2902944_+\|peptide-chain-release-factor-1	gnl\|CDD\|234801	PRK00591, prfA, peptide chain release factor 1; Validated.	0
NZ_CP047422.1\|WP_025011687.1\|2887500_2888592_+\|redox-regulated-ATPase-YchF	gnl\|CDD\|236583	PRK09601, PRK09601, redox-regulated ATPase YchF.	0
NZ_CP047422.1\|WP_025889918.1\|2903957_2904353_+\|SirB2-family-protein	gnl\|CDD\|377264	pfam04247, SirB, Invasion gene expression up-regulator, SirB. SirB up-regulates Salmonella typhimurium invasion gene transcription. It is, however, not essential for the expression of these genes. Its function is unknown.	2.50441e-40
NZ_CP047422.1\|WP_028779724.1\|2905253_2906495_+\|DUF819-family-protein	gnl\|CDD\|114410	pfam05684, DUF819, Protein of unknown function (DUF819). This family contains proteins of unknown function from archaeal, bacterial and plant species.	8.02625e-87
NZ_CP047422.1\|WP_025011684.1\|2883368_2884793_-\|tRNA-(N6-isopentenyl-adenosine(37)-C2)-methylthiotransferase-MiaB	gnl\|CDD\|237673	PRK14325, PRK14325, (dimethylallyl)adenosine tRNA methylthiotransferase; Provisional.	0
NZ_CP047422.1\|WP_159352919.1\|2900593_2901844_+\|glutamyl-tRNA-reductase	gnl\|CDD\|234592	PRK00045, hemA, glutamyl-tRNA reductase; Reviewed.	0
NZ_CP047422.1\|WP_159352920.1\|2902955_2903801_+\|peptide-chain-release-factor-N(5)-glutamine-methyltransferase	gnl\|CDD\|236467	PRK09328, PRK09328, N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional.	1.17731e-125
NZ_CP047422.1\|WP_144167843.1\|2885366_2886635_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|181564	PRK08849, PRK08849, 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional.	0
NZ_CP047422.1\|WP_028779717.1\|2897781_2898729_-\|ribose-phosphate-pyrophosphokinase	gnl\|CDD\|234929	PRK01259, PRK01259, ribose-phosphate diphosphokinase.	0
NZ_CP047422.1\|WP_144216078.1\|2892962_2893493_-\|DUF1768-domain-containing-protein	gnl\|CDD\|378035	pfam08719, DUF1768, Domain of unknown function (DUF1768). This is a domain of unknown function. It is alpha helical in structure. The GO annotation for this protein suggests it is involved in nematode larval development and has a positive regulation on growth rate.	1.37567e-77
NZ_CP047422.1\|WP_109248761.1\|2898808_2899687_-\|4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol-kinase	gnl\|CDD\|234731	PRK00343, ipk, 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional.	0
NZ_CP047422.1\|WP_025011686.1\|2886827_2887415_+\|aminoacyl-tRNA-hydrolase	gnl\|CDD\|235457	PRK05426, PRK05426, peptidyl-tRNA hydrolase; Provisional.	9.8441e-107
NZ_CP047422.1\|WP_159352918.1\|2899683_2900355_-\|outer-membrane-lipoprotein-LolB	gnl\|CDD\|377063	pfam03550, LolB, Outer membrane lipoprotein LolB.	1.13036e-43
NZ_CP047422.1\|WP_071238787.1\|2891766_2892684_-\|IS5-family-transposase	gnl\|CDD\|290455	pfam13737, DDE_Tnp_1_5, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.	1.81565e-54
NZ_CP047422.1\|WP_096140857.1\|2904352_2905144_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|225464	COG2912, COG2912, Uncharacterized conserved protein [Function unknown].	8.40649e-40

>NZ_CP047422.1|WP_144216078.1|2892962_2893493_-|DUF1768-domain-containing-protein
MVDFVDQGNKVKYIFFWGHQEKGEQISKSCFSQWYDAKFEEEGNVFITAEHYMMYNKAKLFGDDIACERILLATNPGAAKAIGREVVGFNQEVWDERRFEIVLNANLAKFAQHTELKSFLLNTGNRILVEASPVDKVWGIGLAQDHPESEIPRRWKGLNLLGFALMEVRDRLRKDL
>NZ_CP047422.1|WP_071238787.1|2891766_2892684_-|IS5-family-transposase
MGKSERNITNWKQYNQALVNRGSVTFWLDEAAVNAWHCTKHHGGRGRGFQFSDTAIETALMLKGIFKLSLRATEGFINSLFQLMKIPLIAPDYSCISKRAKTVNVKYRNPSRGAVAHVVVDATGLKVYGEGEWKMRKHGKEKRRVWRKLHLAIDAATHEIIGAQTSLETVADNEVLPALLAPLRRKLRQVSADGAYDTKACHKLLRRKQAKPTIPPRSNAGYWEPGHPRNEAVDALKAGELKQWKLMNHYHQRSLSETAMYRYKQLISAKLSLRDYNGQVGEALAGVKALNKVIRLGMPVRQKIS
>NZ_CP047422.1|WP_159352916.1|2890654_2891629_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MPNSAREAIMQHMGEAHLYPDSARQALLKRLASYHGVSQEQLIYGNGSSEVLKFAIDAMASAHCQLVMPKPTFDIVADYAKARGLKVTEVPLTAELQTDIAAMQAAVAAHPGPSIVYLCNPNNPTGLLLPKAPVAQWLAKASPALQFIIDEAYGEYAGSDFQSALPFIQNGQKHIVLTKTFSKAWGMAGLRAGYAIAAPEMIAAMQAQASFDNANLFALYGAAAVLDDSAWLAQTRSNNLEAGAIIIATLKRLGLDYLPLNASFIFHRIKGNNEDYRKRMQQAGILVGRTFPGLEGWNRLTLGTPMQMQQVAKEMQRLRLEGLL
>NZ_CP047422.1|WP_109248065.1|2890101_2890560_-|hypothetical-protein
MQVQSILGALFALGFSLSLQAAPGELIINKNAKPKSSNSYIEAVHKELPVAGASEAQVRYAILEGMLSTKGFAWVYEGEGEGYILARFDYRGDTNVMRIEYDANYIQLKYHAALGDFVCKKLIDDICYKNGRGYYNYIKNLRLSIAQELKKS
>NZ_CP047422.1|WP_071237171.1|2889691_2890105_-|hypothetical-protein
MKRILLPLLLNLLWLNPASAETEYQLQRWQNPVPTGGYVQDIPAMLQRAVTRDSWELETAADGTWLARLNNYKGYTVEVEVARQQQELQLSLLSSRCDCKMDQAKIDSWLIRLRRNIALEVTKAARDESLRQKLKVE
>NZ_CP047422.1|WP_025011687.1|2887500_2888592_+|redox-regulated-ATPase-YchF
MGFKCGIVGLPNVGKSTLFNALTKAGIEAANFPFCTIEPNTGVVPVPDARLDALAEIVKPERVLPTTMEFVDIAGLVAGASKGEGLGNKFLANIRETDAIGHVVRCFENDNIVHVANKVDPAGDIEVINTELALADLDSVERAILRQQKRAKGGDKDAKFEVEVLEKLKPVLDEGHMLRTLDLSKEELEAVAYLNLLTLKPTMYIANVSEDGFDNNPHLDTVRAIAEKENAVVVPVCAAIESDLAEMDEEERSEFLEELGLEEPGLDRVIRAGYELLTLQTYFTAGVKEVRAWTVTVGSTAPQAAGKIHTDFERGFIRAQVMAYDDFVQFKGEAGCKEAGKLRVEGKTYIVKDGDVMHFLFNV
>NZ_CP047422.1|WP_025011686.1|2886827_2887415_+|aminoacyl-tRNA-hydrolase
MTEIKLIVGLANPGAEYAQTRHNAGAWYVQELARGCGAQLSADSKYFGLTARVTLKGRDVRLLIPSTYMNLSGKSVAALANFFRIQPEEILVAHDELDMPPGVAKFKLGGGHGGHNGLKDIIAKLGNNKNFYRLRIGIGHPGDKNKVSGYVLGKAPSTEQSLIDAAVDEAVRATDILFAEDMTKAMHRLHSFKAV
>NZ_CP047422.1|WP_144167843.1|2885366_2886635_+|FAD-dependent-oxidoreductase
MIEAKTVTIEHNSVAEAAEKRDSRKGIVTEQHETKDIVIIGGGMVGAATALGLAKLGLEVALVEAFEPEAFDASQPLDVRVSAISVASEALLERLGAFDTLLGMRHVAYRGLETWEMEGCITRFHASQIKAERLGHIVENRLVQLALWQVFDNYPNLTLCCPARVGRMVRSSVGIEVSLDDGRVFDARLLVGADGANSRVRQWAGIGISGWDYSQSCMLINIATECDEQDVTWQQFTPQGPRSLLPLPGKNASLVWYDDAKQIRSLMQLSDSQLKQAIINHFPDRLDPHFEVLAKGSFPLTRRHAQQYYRDNLVILGDAAHTINPLAGQGVNLGFKDVEALIATITQALEKGEDWSKATVLEGFQKQRWFDNQLMMTGMDLFYAGFSNDLLPLKLLRNAGLKLADINTPVKQQVLKYALGLR
>NZ_CP047422.1|WP_045283891.1|2884890_2885214_-|hypothetical-protein
MRKLTSSLIAAALVVPAAFTSGHVLAATTADQMEVITVTYRSSLNYALYQQITETMAGFHLDVLEDIYAQARGSNLEMAEQFYQQQNIQVAANRLPAQLERVLQQPE
>NZ_CP047422.1|WP_025011684.1|2883368_2884793_-|tRNA-(N6-isopentenyl-adenosine(37)-C2)-methylthiotransferase-MiaB
MSKKLHIKTWGCQMNEYDSSKMADLLNEFQGYTLTEEADEADILLLNTCSIREKAQEKVFHQLGRWKTLKDKNPELIIGVGGCVASQEGKAIKERAQCVDIIFGPQTLHRLPEMINQVRSGDQAVIDVSFPEIEKFDRLPEPRAEGPTAFVSIMEGCSKYCSFCVVPYTRGEEVSRPLDDIILEIAQLAEQGVREVNLLGQNVNAYRGLTHDDEICSFAELLRYVAAIDGIDRIRFTTSHPIEFTQDIIDVYEDTPELVSFLHLPVQSGSDRILTQMKRGHMAIEYKSIIRRLRKARPDIQISSDFIIGFPGESKEDFADTMKLIEEVGFDHSFSFIYSARPGTPAADLPDDVDMEEKKQRLAILQDRITQQAQRYSRQMLGTVQRILVEGPSVKNPMELRGRTENNRVVNFEGQPKHIGSFVDVEIVDVYTNSLRGKFVRGEDEMDLRKSLRPSDILAKHNQEDTLGVTQFTP
>NZ_CP047422.1|WP_159352917.1|2896219_2897194_-|transposase
MPRPRYAQVSLEDTPFYHCISRCVRRAFLCGVDDYSGKSYEHRRDWVESRLLELVAVFSIDLCAYAVMSNHLHLVLRVDLKTATEWTLEQVLQRWHLLYSGTLLSLRFLRGETLSDIEYLTLQQTTEVYRQRLMDISWFMRALNEPIARQANREDGCSGRFWEGRFKSQALLDDAAVLACMAYVDLNPIRAGIAKTPEDSDYTSIQRRIQAAMQGKNTPELLPFVGNERLNMPQGLYFEAKDYLQLVDDTGRIIRHDKRGQITASTTTILNRLNIPIDNWLKLTTDFSRLFKGPVGTLESLTDYCTHLQRRRRQGAANCQKLFS
>NZ_CP047422.1|WP_028779717.1|2897781_2898729_-|ribose-phosphate-pyrophosphokinase
MPDIKLFAGNATPSLAKKIADRLFCKLGDAEVGRFSDGEISVQINENVRGADVFIIQSTCAPTNDNLMELIVMVDALRRASAGRITAVIPYFGYARQDRRVRSARVPITAKVVADFLSSVGVDRVLTCDLHAEQIQGFFDVPVDNVFGSPVLLEDMLAKKLDNPVVVSPDIGGVVRARAVAKLLDDSDLAIIDKRRPQANVAQVMHIIGDVQGRDCIIVDDMIDTGGTLCKAAEALKEHGANRVFAYATHPVFSGNAASNIVNSVIDEVIVTDTVPLSPEMLKTGKVSQLTMSAVLAEAIRRVSNEESISAMFQH
>NZ_CP047422.1|WP_109248761.1|2898808_2899687_-|4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol-kinase
MSSLDQTSKPNSLSLGWPAPAKLNLFLHINGRREDGYHELQTLFQFLDHGDLLDFKVTANGELKLHSNLGAAVPDSDNLILKAAKSLQQASGCKLGAEIWLDKKLPMGGGLGGGSSDAATTLVALNALWQTGLSETELEQIGLKLGADVPVFIKGLAAFAEGVGEKLQPVEPAEPWYLVLVPEAHVSTEKVFHDPDLPRDTPKLSLEQLLSAPWQNDCQALVCRHYPQVAKALGWLLEYAPSRMTGTGACVFGEFEKQQQALDCLAQLPPSFKGFVAKGINRSPLQSRLARL
>NZ_CP047422.1|WP_159352918.1|2899683_2900355_-|outer-membrane-lipoprotein-LolB
MIILKYFTKTCFTPLSTLRLLLPLLLLGLLSACSSLPDARWQATQVKHAEQAKAWELKGKLAVKTPEEKFSTNLYWLHTPTTEELRLTTMLGTSVMLLKSGPDGALLELDGKVYRDRDPQRLLDGLSSWSIPLNALPRWVLGLSAADTELLLTNNDGNPQSLEDGSVSPPWQVKYLSWQQQSGADIPRLLKLNRGALELKIQLTEWQALEAQSTITTKESQQP
>NZ_CP047422.1|WP_159352919.1|2900593_2901844_+|glutamyl-tRNA-reductase
MSLVAIGINHKTATVDLREKVAFAPDKIHEAMRSLTKETQSGEAVIVSTCNRTELYCNTENAEQVVRWLEDYHGLSHEEVAPCLYQHCGQPAVQHLMRVASGLDSLVLGEPQILGQVKQAFAKAKESGTVALTLDRLFQNTFAVAKKVRTETEIGTAAVSVAFAAVSMAKHIFSSLAATKVLLIGAGETIELVARHLKENGVTSMVVANRTISRAEAMCEEFNAQAITLEQIPDFLPKADIVISSTASPLPILGKGMVEKALKQRRHQPMLLVDIAVPRDIEAEVGDLDDAFLYTVDDLQSIIEQNMASRREAAEQAEVIAEEHSHQFMEWVRSLESVDSIREYRTQSMAIKDELVERAMNKLAQGADTEQVLLELANRLTNRLIHAPTQALTAASRQGDLNALGQLRTALGLDKH
>NZ_CP047422.1|WP_025011691.1|2901858_2902944_+|peptide-chain-release-factor-1
MKESVIRKLEGLLERNEEVLALLSDADVIADQDRFRALSREYAQLEDVVKGFKAYQQAQADLQTAQEMLAEEDPELKEMAQEEIKAARAQLEQLEGELQILLLPKDPNDASNAFLEIRAGAGGDEAAIFAGDLFRMYSRYAESQRWQVEVMSASEGEHGGFKEVIAKVSGDGVYGKLKFESGGHRVQRVPETESQGRVHTSACTVAVMHEVPEAQAVEINPAELRIDTFRSSGAGGQHVNKTDSAIRITHLPTGLVVECQDQRSQHKNKAQALSVLAARLQAAEDEKRRSAEESTRRSLVGSGDRSERIRTYNFPQGRVSDHRINLTLYRLNEVIEGDLEQLLEPLMQEHQADMLAALSDE
>NZ_CP047422.1|WP_159352920.1|2902955_2903801_+|peptide-chain-release-factor-N(5)-glutamine-methyltransferase
MTKLNIAEALQWASSMLAASSESAHADAEALLLHCLGKSRSFIYTWPERSLSAEQHKQFTQMVLRRSQGVPVAHIVGEREFWSLPFIVNESTLIPRPDTEILVETALNLPLSDDIAVLDLGTGTGAIALALAHERQGWQVTAVDKVEAAVELACANRDNLKLPQVEILQSDWFSAVQGRKFQLIVSNPPYIEEDDEHLEMGDVRFEPRSALTAADQGFADLFHIAAHAREHLLPGGYLLLEHGYAQAVNLREKLAELGYQQVATVRDFGSNERCTLGLWPG
>NZ_CP047422.1|WP_025889918.1|2903957_2904353_+|SirB2-family-protein
METFYSLYPAVKHLHMTLIAVSVLLFIVRFVLKLRQSAIMDKKLLKVGPHVIDTFLLLSGLTLCFMIKQYPFVDPWMTEKIGAVVAYILLGVMALKSNRNLIFRIFAFLGALGWVVYAAKLAHFKQAVILG
>NZ_CP047422.1|WP_096140857.1|2904352_2905144_+|tetratricopeptide-repeat-protein
MQQYSLKQDELSLPESAFELCQHLGFGLAKQANWAWLELSGSVLSHYLVDQQRRFQALLNWFYKDLGFAPREDYFSRQAADLGQCILSRQGNSTTLATVLMLLGKQLDLKFDPVLLPGTTVLACHVAGELIYLDPLRGERLSKERLHALVRGELGNSAPLKASYLKPVGTQRLMTRMLHELKAGAIVAHEFEVAMECCNLLLEWHADDLSLHRERAFIAQQLGAIHVASADLQYFVDNSPHDPVVELVKMQLRELGDDPQTFH
>NZ_CP047422.1|WP_028779724.1|2905253_2906495_+|DUF819-family-protein
MTALVTNDATALGILAAILGFVFYTNSSSHPFWQKFYRFIPALLLCYFLPSLLNTFGIVDGSTSKLYYVASRYLLPACLVLLILSVDLKAILGLGPKAVVMFLTGTMGIVIGGPIALLIMSAIDPTLTAGHGPDAVWRGMTTLAGSWIGGGANQAAMKEIYEVGGNIFSVMVTVDVIVANIWMAVLLFMASRAKEIDAKTGADTSAIESLKAKVEQYHAENARIPSLRDIMLIVAVGFGITGLAHVGADLLAPWFATNYPWTEQYSLTSGFFWLVVIVTTIGLLLSFSPARHLEAAGASKIASAYLYILVATIGLHMDVSQILDTPIYFLVGIIWMLVHSGLMLLVAKLIRAPLFYMAVGSQANVGGAASAPVVAAAFHPALAPVGVLLAVFGYALGTYMAWLCGQLLQAVAG

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Crispr_ID: NZ_CP047422_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047422_3

3400865-3401131

Orphan

Consensus_repeat	Method
GAAGGCAAGTGTGGCGAAGGGATGAAG	CRISPRCasFinder

3 spacers

The CRISPR arrays of NZ_CP047422_3

>merge|NZ_CP047422|3|3400865-3401131|CRISPRCasFinder
GAAGGCAAGTGCGGCGAAGGTAAATGTGGTGATAAGAAAGCCAAGGAAGCCGAGCACAAGGGCCGTGAGGGTAAATGCGGCGAAGGCAAGTGTGGCGAAGGGATGAAGAAAGCTGCCGAAGGCAAATGTGGTGAGGGCATGAATAAGGCCGCCGAGGGCAAGTGTGGTGAAGGCAAGTGTGGCGAAGGAATGAAGCATTCCGCCGAGGGTAAAGCCAAAGCCGAAGCCAATAAGGTCAAAGAAGGCAAGTGTGGTGAAGCCAAGTGC

>NZ_CP047422|3|3|3400865-3401131|CRISPRCasFinder
GAAGGCAAGTGCGGCGAAGGTAAATGT	GGTGATAAGAAAGCCAAGGAAGCCGAGCACAAGGGCCGTGAGGGTAAATGCGGC
GAAGGCAAGTGTGGCGAAGGGATGAAG	AAAGCTGCCGAAGGCAAATGTGGTGAGGGCATGAATAAGGCCGCC
GAGGGCAAGTGTGGTGAAGGCAAGTGT	GGCGAAGGAATGAAGCATTCCGCCGAGGGTAAAGCCAAAGCCGAAGCCAATAAGGTCAAA
GAAGGCAAGTGTGGTGAAGCCAAGTGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047422.1\|WP_159353025.1\|3388301_3390164_+\|Fe-S-protein-assembly-chaperone-HscA	unknown	unknown	gnl\|CDD\|235360
NZ_CP047422.1\|WP_109247398.1\|3402041_3402830_+\|DUF2063-domain-containing-protein	unknown	unknown	gnl\|CDD\|225760
NZ_CP047422.1\|WP_025011503.1\|3403677_3404073_+\|response-regulator	unknown	unknown	gnl\|CDD\|381099
NZ_CP047422.1\|WP_025011505.1\|3407900_3408230_+\|YbaB/EbfC-family-nucleoid-associated-protein	unknown	unknown	gnl\|CDD\|234669
NZ_CP047422.1\|WP_045282655.1\|3408960_3409422_-\|carboxymuconolactone-decarboxylase-family-protein	unknown	unknown	gnl\|CDD\|225039
NZ_CP047422.1\|WP_025011499.1\|3399014_3399356_-\|conjugal-transfer-protein-TraR	unknown	unknown	gnl\|CDD\|224648
NZ_CP047422.1\|WP_025011494.1\|3390172_3390508_+\|ISC-system-2Fe-2S-type-ferredoxin	unknown	unknown	gnl\|CDD\|131062
NZ_CP047422.1\|WP_159353026.1\|3404841_3407769_+\|DNA-polymerase-III-subunit-gamma/tau	unknown	unknown	gnl\|CDD\|237863
NZ_CP047422.1\|WP_025011504.1\|3404168_3404720_+\|adenine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|235028
NZ_CP047422.1\|WP_025011493.1\|3387693_3388218_+\|co-chaperone-HscB	unknown	unknown	gnl\|CDD\|179914
NZ_CP047422.1\|WP_025011495.1\|3390640_3391540_+\|30S-ribosomal-protein-S6--L-glutamate-ligase	unknown	unknown	gnl\|CDD\|182468
NZ_CP047422.1\|WP_025011498.1\|3396151_3398803_+\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|238657
NZ_CP047422.1\|WP_144225224.1\|3393032_3395702_+\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|238657
NZ_CP047422.1\|WP_109247399.1\|3401205_3402042_+\|DUF692-domain-containing-protein	unknown	unknown	gnl\|CDD\|235447
NZ_CP047422.1\|WP_025011497.1\|3392212_3392644_+\|nucleoside-diphosphate-kinase	unknown	unknown	gnl\|CDD\|179085
NZ_CP047422.1\|WP_109247397.1\|3403215_3403590_+\|YbaN-family-protein	unknown	unknown	gnl\|CDD\|377291
NZ_CP047422.1\|WP_093983177.1\|3403010_3403130_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047422.1\|WP_039033855.1\|3408243_3408843_+\|recombination-protein-RecR	unknown	unknown	gnl\|CDD\|234616
NZ_CP047422.1\|WP_025890163.1\|3399482_3400436_-\|tRNA-dihydrouridine-synthase-C	unknown	unknown	gnl\|CDD\|236713
NZ_CP047422.1\|WP_025011496.1\|3391621_3391819_+\|Fe-S-cluster-assembly-protein-IscX	unknown	unknown	gnl\|CDD\|377339

Protein	Function_ID	Function_description	E-value
NZ_CP047422.1\|WP_159353025.1\|3388301_3390164_+\|Fe-S-protein-assembly-chaperone-HscA	gnl\|CDD\|235360	PRK05183, hscA, chaperone protein HscA; Provisional.	0
NZ_CP047422.1\|WP_109247398.1\|3402041_3402830_+\|DUF2063-domain-containing-protein	gnl\|CDD\|225760	COG3219, COG3219, Uncharacterized protein conserved in bacteria [Function unknown].	5.17355e-36
NZ_CP047422.1\|WP_025011503.1\|3403677_3404073_+\|response-regulator	gnl\|CDD\|381099	cd17546, REC_hyHK_CKI1_RcsC-like, phosphoacceptor receiver (REC) domain of hybrid sensor histidine kinases/response regulators similar to Arabidopsis thaliana CKI1 and Escherichia coli RcsC. This family is composed of hybrid sensor histidine kinases/response regulators that are sensor histidine kinases (HKs) fused with a REC domain, similar to the sensor histidine kinase CKI1 from Arabidopsis thaliana, which is involved in multi-step phosphorelay (MSP) signaling that mediates responses to a variety of important stimuli in plants. MSP involves a signal being transferred from HKs via histidine phosphotransfer proteins (AHP1-AHP5) to nuclear response regulators. The CKI1 REC domain specifically interacts with the downstream signaling protein AHP2, AHP3 and AHP5. The plant MSP system has evolved from the prokaryotic two-component system (TCS), which allows organisms to sense and respond to changes in environmental conditions. This family also includes bacterial hybrid sensor HKs such as Escherichia coli RcsC, which is a component of the Rcs signalling pathway that controls a variety of physiological functions like capsule synthesis, cell division, and motility. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	6.42647e-18
NZ_CP047422.1\|WP_025011505.1\|3407900_3408230_+\|YbaB/EbfC-family-nucleoid-associated-protein	gnl\|CDD\|234669	PRK00153, PRK00153, YbaB/EbfC family nucleoid-associated protein.	2.65258e-43
NZ_CP047422.1\|WP_045282655.1\|3408960_3409422_-\|carboxymuconolactone-decarboxylase-family-protein	gnl\|CDD\|225039	COG2128, COG2128, Uncharacterized conserved protein [Function unknown].	1.21438e-20
NZ_CP047422.1\|WP_025011499.1\|3399014_3399356_-\|conjugal-transfer-protein-TraR	gnl\|CDD\|224648	COG1734, DksA, DnaK suppressor protein [Signal transduction mechanisms].	0.000536649
NZ_CP047422.1\|WP_025011494.1\|3390172_3390508_+\|ISC-system-2Fe-2S-type-ferredoxin	gnl\|CDD\|131062	TIGR02007, 2Fe-2S_ferredoxin, ferredoxin, 2Fe-2S type, ISC system. This family consists of proteobacterial ferredoxins associated with and essential to the ISC system of 2Fe-2S cluster assembly. This family is closely related to (but excludes) eukaryotic (mitochondrial) adrenodoxins, which are ferredoxins involved in electron transfer to P450 cytochromes. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	6.36068e-59
NZ_CP047422.1\|WP_159353026.1\|3404841_3407769_+\|DNA-polymerase-III-subunit-gamma/tau	gnl\|CDD\|237863	PRK14949, PRK14949, DNA polymerase III subunits gamma and tau; Provisional.	0
NZ_CP047422.1\|WP_025011504.1\|3404168_3404720_+\|adenine-phosphoribosyltransferase	gnl\|CDD\|235028	PRK02304, PRK02304, adenine phosphoribosyltransferase; Provisional.	8.39304e-99
NZ_CP047422.1\|WP_025011493.1\|3387693_3388218_+\|co-chaperone-HscB	gnl\|CDD\|179914	PRK05014, hscB, co-chaperone HscB; Provisional.	1.0643e-90
NZ_CP047422.1\|WP_025011495.1\|3390640_3391540_+\|30S-ribosomal-protein-S6--L-glutamate-ligase	gnl\|CDD\|182468	PRK10446, PRK10446, 30S ribosomal protein S6--L-glutamate ligase.	9.17128e-154
NZ_CP047422.1\|WP_025011498.1\|3396151_3398803_+\|TonB-dependent-receptor	gnl\|CDD\|238657	cd01347, ligand_gated_channel, TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.	4.39785e-56
NZ_CP047422.1\|WP_144225224.1\|3393032_3395702_+\|TonB-dependent-receptor	gnl\|CDD\|238657	cd01347, ligand_gated_channel, TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.	2.01157e-35
NZ_CP047422.1\|WP_109247399.1\|3401205_3402042_+\|DUF692-domain-containing-protein	gnl\|CDD\|235447	PRK05409, PRK05409, hypothetical protein; Provisional.	5.82979e-157
NZ_CP047422.1\|WP_025011497.1\|3392212_3392644_+\|nucleoside-diphosphate-kinase	gnl\|CDD\|179085	PRK00668, ndk, mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-; Validated.	3.33048e-92
NZ_CP047422.1\|WP_109247397.1\|3403215_3403590_+\|YbaN-family-protein	gnl\|CDD\|377291	pfam04304, DUF454, Protein of unknown function (DUF454). Predicted membrane protein.	3.35973e-42
NZ_CP047422.1\|WP_039033855.1\|3408243_3408843_+\|recombination-protein-RecR	gnl\|CDD\|234616	PRK00076, recR, recombination protein RecR; Reviewed.	4.54651e-111
NZ_CP047422.1\|WP_025890163.1\|3399482_3400436_-\|tRNA-dihydrouridine-synthase-C	gnl\|CDD\|236713	PRK10550, PRK10550, tRNA dihydrouridine(16) synthase DusC.	1.74089e-137
NZ_CP047422.1\|WP_025011496.1\|3391621_3391819_+\|Fe-S-cluster-assembly-protein-IscX	gnl\|CDD\|377339	pfam04384, Fe-S_assembly, Iron-sulphur cluster assembly. This family of proteins is likely to be involved in the assembly of iron-sulphur clusters. It may function as an adaptor protein. In Escherichia coli IscX forms part of the isc operon, which encodes genes involved in iron-sulphur cluster assembly. Its structure is entirely alpha helical, and it contains a modified wing-helix structure, usually found in DNA-binding proteins. It binds to Fe2+ and Fe3+ ions and to the cysteine desulfurase IscS, the same surface of the protein is involved in both binding to iron and to IscS.	6.09476e-29

>NZ_CP047422.1|WP_025890163.1|3399482_3400436_-|tRNA-dihydrouridine-synthase-C
MRIILAPMEGVVDNLMRELLSAINPYDLMVTEFVRVVDQLLPEKVFHRLCPELLQGGMTLSGTPVRVQLLGQEPGWMAENALRAIELGSQGVDANFGCPAKMVNRSKGGAVLLQYPEQIHKIVKAMRQAVPEPHAVTAKIRLGFEDKSLFMENALAIYEAGATELAVHARSKKDGYRPPAYWEYITEIREKLAIPVIANGEIWNREDALRCMEVTGCDSIMVGRGAISLPNLADHIKNGAMQYSWQQTLALLMSYSQKELSGRKSCYYPARIKQWFSYLNRQYPQADTLFRELRVHKQTDDIVATLSRAHREIDDKM
>NZ_CP047422.1|WP_025011499.1|3399014_3399356_-|conjugal-transfer-protein-TraR
MSSSHIRQALSALEIDLRKEIMVLGPHWDPQMSLSDLIETMIQADLCKHPLYHRLLRLDAALCQLDLGLYGLCADCEAEIEAYRLDRDPTEQRCERCHEQYKHEHRQELRLNH
>NZ_CP047422.1|WP_025011498.1|3396151_3398803_+|TonB-dependent-receptor
MSSISLTAKAVRRGLLAAAVTGIAFSGYATAEEAKEGKVERIEVTGSRIKQVDMETASPVTVITAADLKVTGETSVADVLNNSSINSFGSWRGMSGYGAGASATSDVDLRGLGSQATLILLDGRRMPGTSSSSGTVADTSSIPMAIVERIEILRDGASAVYGSDAVAGVINIITKKDFEGVELNYTGESPDVEGGDSSRFSVAAGFSTDKGNITLTFEHYDTTSVYDKDVWRFDDPSWNGISSYSVIPRATYIGADGKSANYTNSELCSQAPNVIDGTDGANAGTCYYDFGKVTKLFGNVNRNSILSNFNYQLTDDIQFRGRASASLSETNTRYAGTPVSTNAPTMAADNPMNPLGTDITEIRMRSVQIGERDTTTETNSIDFLAGLVGYWDVGNGIDWEINAQHTRSTTDSFNYNLINDNIVQDLINTGNYDVFNTTGMSYEDWDAQMADLYGQAAHTGVYQAQFNSTQFDGLLSGMLYEGNGITLAAVVGAEYEMIEFVQLSDPQSAAGIISGGSGGDDVDATRDRSSGYLELQSSLPYNVDLSAAVRYERYEQEGNIASGFASSTFDSVVPKFSASWRPVDSLLLRASWGESFRAPNMGEMFSGEALSFERTLDTVWCSANPGADENYCSPSNQYKTFYGGNPDLKAEEGESLTLGFVWNVTDDWSIETSYYDISYDSKIEVVDVADLIREEEANGGSPYIIRGSDGKIETIHSQYRNLSALETSGIDFVTSYNQETDFGDFRLKLEMTHVLEYKTKADAESDFFDEAGLQDKPEWRGSASINWSRDNWSAAWTTYYIGGQDSGAVEYNNEYLINVPSYFKHNVQVSYAHDWNGSITLGVNNAFDEEAPTWYNYADYRDVNTGLYDVLGRTWFVTINQKF
>NZ_CP047422.1|WP_144225224.1|3393032_3395702_+|TonB-dependent-receptor
MSTQTAVAKAIRFSLFAFVSTSIPTMVYAADDAQATEQVERIEVTGSRIKRTDMENASPVVVMSAADIEKGGFNSVQDVLGNLSQNSGGSMTQQEVHGFTPAASSVNLRGVGAGRVLTLINGKRVPKYPFGAGGTDSFVDTANIPLGAIERIEILTTGASAIYGSDAMGGVINIILKKDVEQTTFKYRFSDTDEGGLRNNQFSFMTGVSSDTANLTFFAEYEDRTALKGTDRPEWGTDIVDGQPYSGYSSYGANLVQDLGNNKTSLTKTLSPAECEARGYVVMENGRCGFDRSKQRDFLPEQKRYSTMINLTKELNADHQLYSRIDYTHSSTFTEIESATVGTDFMFNVAGDKVTIANKDKGLSQTFDKDTAFGGDFANAADGDYYYTRRMSELGPRTSDFETNNFSFIIGSKGFLTDTIEYDTSWSIARQTVESRSNGSPTYQSTFDYLTSGDSGKSLLDVISPEDAALLNYEGNKKGQSTLSSFSAGINGDAFELAGGTAAYAVGIEYSKEWFYDKSDSFTSNGGVIGKGGSSAEGEREQYAAYAELALPLLDQLTMTLAGRYDYYDDESDVGGQFTPQVSLEYRPIDSLMLRALYAETFRAPDMQRLFGDPTTGYSTVIDTPRCEAYGECDKIESLPIAIGANPELEAEEGKNYNLGLVWDYEGINLTVDYWMVEIDNLVNDPSAQYILDHADAFADKIERDSNGKLLKVNTQAMNMSSRETAGIDFSLGYRYETESYGEFSSRLEGTYLTRWKEKLTPDSEELDLIDGEGSAPQLRANLNLGWSYNDFSTNILFKYIDSMNGERMDYFVSEGLDSTYPVKIDSHVEVNLAASYFIYDNLKVSAGINNLFDSGPEIDYTQSSWPHYPRAYYNVIGREYYAGVEFTF
>NZ_CP047422.1|WP_025011497.1|3392212_3392644_+|nucleoside-diphosphate-kinase
MAIERTFSIIKPDAVAKNHIGAIYNRFETAGLKIVAAKMVHLTKEQAEGFYAEHSERPFFGALVSFMTSGPIMVQVLEGENAVLANREIMGATNPAEAARGTLRADFADSIDENAVHGSDALASAEREIAYFFAADELCPRTR
>NZ_CP047422.1|WP_025011496.1|3391621_3391819_+|Fe-S-cluster-assembly-protein-IscX
MGLKWIDSLDLALELLEAHPDVDPEQLHFPELYEWILALEAFDDDPKRCSEKILEAVQQCWIEEK
>NZ_CP047422.1|WP_025011495.1|3390640_3391540_+|30S-ribosomal-protein-S6--L-glutamate-ligase
MQIAILSQNKTLYSTRRLVEAAQERGYQVQVINPLECYMNISMQQSSIHIGGVELPSFDAVIPRIGAGITFYGTAVVRQFEMMATYTLNSSMGISRSRDKLRSMQLLSRKGIGLPVTGFANKPSDIPDLIDMVGGAPLVIKLLEGTQGIGVVLAETRKAAESVIEAFMGLKANIMVQEYIKEAQGADIRCFVLGDKVIAAMKRQALPGEFRSNLHRGGTATLVKLSPEERSIAVRAAKTMGLNVAGVDILRSNHGPVVMEVNSSPGLEGIEAATGKDVAGAIIEFIAKQRRKGKTPSEA
>NZ_CP047422.1|WP_025011494.1|3390172_3390508_+|ISC-system-2Fe-2S-type-ferredoxin
MPQIVFLPHEELCPEGAVVEAEVGESILDVALKNGINIEHACEKSCACTTCHVIVREGFDELEPSDDLEDDMLDKAWGLEPESRLSCQAKVVEGDMVVEIPKYTVNMVSEG
>NZ_CP047422.1|WP_159353025.1|3388301_3390164_+|Fe-S-protein-assembly-chaperone-HscA
MALLQIAEPGQMAAPHQHRLAAGIDLGTTNSLVAAVRSSEASTLADEQGRHSLPSVVHYGEQGVRVGHDALADSAKDPENTIVSVKRFMGRSLADVQSGEQAFPYQFEASENGLPLFVTRAGKMNPVQVSAEVLRPLIARAESTLGGPLEGVVITVPAYFDDAQRQGTKDAAALLGIKVLRLLNEPTAAAIAYGLDSGQEGVIAVYDLGGGTFDISILRLNRGVFEVLATGGDSRLGGDDFDELLQGLLRERMALKSLSSQEARQLLMEARRVKEALTDSDSTIAKLTLKDGSECEAEVSRSEFDQLINTLVKKTIQGCRKALRDAGVDTDEVLETVMVGGSTRVPLVREMVGDFFGRAPLTSIDPDRVVAIGAAVQADILVGNKPDSDLLLLDVIPLSLGIETMGGLVEKVIPRNTTIPVARAQEFTTFKDGQSAMAFHVVQGERELVADCRSLARFTLKGIPPLAAGAAHIRVTFQVDADGLLSVTAMEKSTGVQSSIQVKPSFGLSDTEIAGMLKDSMQNAKEDIELRMLTEQRVEAARVLESLHSALAKDGELLSQEERALVDRAMADLSETAANGDVDAIKAAIEAVDAQTQEFAARRMDNSIRAALKGQSVDNI
>NZ_CP047422.1|WP_025011493.1|3387693_3388218_+|co-chaperone-HscB
MNYFELFDLTPSFDVDTAELASRYRDLQRAVHPDKFANASEQQKLLAISRTAQINDAFQTLKDPIRRAEHMLALKGVDISHETTTVKDTAFLMQQMEWREALEEIGQSGDAQSDIDELDVSFAAYRKQVTELLRNQLHSSKEADAIAAADQVRKLKFMAKLQDELQRAQDALFD
>NZ_CP047422.1|WP_109247399.1|3401205_3402042_+|DUF692-domain-containing-protein
MNNCVGLGLRREMLAEFCQAAPKEADFFEVAPENWMRLGGKFGKQFRQLTEKHSFYCHGLSLSIGSPAPLDLAFIKEIKRFLDLHQIDVYSEHLSYCSADGHMYDLMPIPFTYEAVRHVSARVKQVEAILERPLILENVSFYAAPGAEMTEQEFVCAVLEEADCRLLLDVNNIYVNSVNHGYDPAAFLAAMPSERIAYLHIAGHYQQDEDLIIDTHGADIIDPVWQLLAECYRLHGVHPTLLERDFNIPATRVLCQELKQIDTLQHQALGVFAQERRA
>NZ_CP047422.1|WP_109247398.1|3402041_3402830_+|DUF2063-domain-containing-protein
MALAQLQQAFVAYLRRDDMPLPAGTDERHMRVYRELFFNNVNGFVSNAYPVLKSLHTEAQWLALVKDFFARHDCQSPLFIDIAAEFLDYLCREQTSALDAMPFMLELAHYELLELQVSVAVDSSAPWLEPTELQALEQLAAKLQLAVTARVAQYQFEVDRISPDFRPDSVAATPVFFCVYRDREEEVRFLRLNPMTAQLLAKLQQTPLSFTRLLAWLAETFPQFPEPQLCQGALTTLAELAVLGIIRKQPTAAIQATTPCQA
>NZ_CP047422.1|WP_093983177.1|3403010_3403130_+|hypothetical-protein
MSQPFKDPFNILYFLGFILVMLLPTLPASLSWLKHAGLI
>NZ_CP047422.1|WP_109247397.1|3403215_3403590_+|YbaN-family-protein
MVIKRGFFLISGILSLAMGLLGIVLPVLPTVPFILLAAFCFARSSERLHDWLHSHPWFAQPLADWHSRKAMRKGLKRRAFLVSGASFALSIVLVPLWWVKLLLAVCCVCLLLFLWQIPELEDSE
>NZ_CP047422.1|WP_025011503.1|3403677_3404073_+|response-regulator
MSFNILLVDDNNISQQALAELFQSQGWHCTLATNGMQGLACAERQNFDAVISGFFMPLLDGPHFIPLLRQLDGYANLPVVVLSTHSQEEVAASMDMSQVNGFWRKPLNCDTKQQLLDHLSTEIVAWRIKAA
>NZ_CP047422.1|WP_025011504.1|3404168_3404720_+|adenine-phosphoribosyltransferase
MAMNSDSLSLIKQSIKTIPDYPKAGILFRDVTSLLEDPVAYQLSIRLLVDHYKDHGFTKVVGTEARGFLFGAPLALELGVGFIPVRKPGKLPRETIAESYELEYGHDTLEMHVDAIVPGDKVLVIDDLLATGGTIEATVKLIRRLGGEVKDAAFVISLPDLGGEQRLTEQGLELVKLCEFDGE
>NZ_CP047422.1|WP_159353026.1|3404841_3407769_+|DNA-polymerase-III-subunit-gamma/tau
MSYQVLARKWRPASFDQVVGQSHVLHALTNALSQQRLHHAYLFTGTRGVGKTSLARLFAKGLNCETGITAKPCGQCSACQEIAQGRFVDLIEVDAASRTKVDDTRELLDNVQYRPTQGRFKVYLIDEVHMLSRSSFNALLKTLEEPPEHVKFLLATTDPQKLPVTVLSRCLQFNLKSLDQTEMAGQLQHILQSEGLKFETSALTLLARAANGSMRDALSLTDQAIAFGAGQVMLEQVQTMLGAIDERQVLALFDALLTGDIAKMMQEVAKVLAFGADAAEVLRSLLELLHQITLSQFAPAAANLSLFGPRINHYGENLTPEQVQLYYQLLLSGRKELPYAPDPKSGLEMALLRAVAFVPETPPKRWQRGEVADLSALENSSSAAAPATVGAPNQPLESNNVDEIKPQAASAQSVTSQVVKAQAEKMQAAKMPTQVSPAAETQASNIDSQMAANEGEDADEQALLAEQALLLSQAGSMGFRNEASEPAKVAESLPARQPTAAKPHEPVSQAETSTISDEQQSQDDFYAAMGYSLQGEGQDSSLDFYQQQMSMDGQMPSAADKSTSEASLSNKPSSEPVPADANIDSGSDDILGDDLLDQVLATRDLLLSDIEAASPKDGEEKKPLLERRSAAAAPESDAVAATQSEAAAELGNSPELSKSPELSKSPERVDSLEPSNSPEPSQAETQTPVAGEVPSESGPNYVAALKEDRPPWEDAPEGAVEAGREAMQDSETVQNVAFPQAEPESVPEFLPEPEPEPQPQHTAQQTAQEAAPQAVDEPGHELKNELKNELGQGSGQSATVNTVNTGARPASEPCQALGPESAEAFAHAPPSGHPQDLYWYKLMSALEIGGRVRQLAVNSVCERIAEPLPLLLKPDQKHLAADSAIKQLEEALSKLFGKPCRTEIVVGVDDQRETPLEIRHRFHQELLSGAHASLMNDENIQWLVSHMGAELDQDTLGYPPELLSQRANLIADKAP
>NZ_CP047422.1|WP_025011505.1|3407900_3408230_+|YbaB/EbfC-family-nucleoid-associated-protein
MFGKGGMGNLMKQAQMMQEKMAKMQEEIARMEVTGESGAGLVKVTMTGSHNVRKVEIDPSLLEDDKEMLEDLIAAACNDAARRVEENQKSKMAEVTGGMQLPPGMKMPF
>NZ_CP047422.1|WP_039033855.1|3408243_3408843_+|recombination-protein-RecR
MKFSPLVDELIQSLRCLPGVGPKSAQRMAFQLLERERKAGLKLAEALERAMKEVGHCQSCRTFTEETLCPICASPRRGNADTICVVETPADVLAIEAGGHFSGRYFVLLGHLSPLDGVGPEELGLALLEEHLAKGEIAELILATNPTVEGDATAHFIADIAHRYQVKVSRIAHGVPVGGELEYVDSTTLALSFNGRLPL
>NZ_CP047422.1|WP_045282655.1|3408960_3409422_-|carboxymuconolactone-decarboxylase-family-protein
MMKRLDYANAAPQAMKILYQQESYFHQQFNASETMSVTIWELVKLRVSQINQCAFCIDMHSKDALKYGEKAERIFGLNAWRDMPIYSYEEGVALGWAEKLTAGLSISDEEYQQVLDCFGPQAMTDLTIAINAINSWNRIVKVFKPEVGSYQPQ

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Crispr_ID: NZ_CP047422_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047422_4

3737258-3737374

Orphan

Consensus_repeat	Method
CAAGAATTATGGGTGTCCCCATTTTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP047422_4

>merge|NZ_CP047422|4|3737258-3737374|CRISPRCasFinder
CAAGAATTATGGGGGCAAGAATTATGGGTGTCCCCATTTTGTTCCTTTTCAAAGGCTCCATTCAAGCCTAGACAAGGTGAGATAAACCTGCCAAGAATTATGGGTGTCGCCATTTTG

>NZ_CP047422|4|4|3737258-3737374|CRISPRCasFinder
CAAGAATTATGGGGGCAAGAATTATG	GGTGTCCCCATTTTGTTCCTTTTCAAAGGCTCCATTCAAGCCTAGACAAGGTGAGATAAACCTGC
CAAGAATTATGGGTGTCGCCATTTTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047422.1\|WP_144166661.1\|3742234_3742705_+\|YaiI/YqxD-family-protein	unknown	unknown	gnl\|CDD\|178882
NZ_CP047422.1\|WP_159353106.1\|3734280_3734667_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|341046
NZ_CP047422.1\|WP_159353107.1\|3736211_3737186_-\|transposase	unknown	unknown	unknown
NZ_CP047422.1\|WP_159353104.1\|3727625_3728819_-\|ISL3-family-transposase	unknown	unknown	gnl\|CDD\|376574
NZ_CP047422.1\|WP_025887666.1\|3740126_3740702_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|380339
NZ_CP047422.1\|WP_159353108.1\|3737550_3738573_+\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|226077
NZ_CP047422.1\|WP_159353383.1\|3738824_3739997_-\|benzoate/H(+)-symporter-BenE-family-transporter	unknown	unknown	gnl\|CDD\|281578
NZ_CP047422.1\|WP_025011191.1\|3746040_3746502_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047422.1\|WP_071237479.1\|3745040_3745877_+\|S-formylglutathione-hydrolase	unknown	unknown	gnl\|CDD\|131868
NZ_CP047422.1\|WP_044734647.1\|3720556_3722509_-\|acetate--CoA-ligase	unknown	unknown	gnl\|CDD\|234677
NZ_CP047422.1\|WP_045284110.1\|3732780_3733368_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047422.1\|WP_159353102.1\|3718937_3720107_+\|porin	unknown	unknown	unknown
NZ_CP047422.1\|WP_159353109.1\|3740878_3741253_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047422.1\|WP_159353111.1\|3743905_3745030_+\|S-(hydroxymethyl)glutathione-dehydrogenase/class-III-alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|176260
NZ_CP047422.1\|WP_159353103.1\|3726607_3727384_-\|phosphatase-PAP2-family-protein	unknown	unknown	gnl\|CDD\|239490
NZ_CP047422.1\|WP_101059344.1\|3733891_3734302_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226867
NZ_CP047422.1\|WP_159353110.1\|3741267_3742053_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047422.1\|WP_159353105.1\|3729030_3732255_+\|protease	unknown	unknown	gnl\|CDD\|143478
NZ_CP047422.1\|WP_044734646.1\|3723108_3726537_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|223664
NZ_CP047422.1\|WP_028781419.1\|3742879_3743773_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176159

Protein	Function_ID	Function_description	E-value
NZ_CP047422.1\|WP_144166661.1\|3742234_3742705_+\|YaiI/YqxD-family-protein	gnl\|CDD\|178882	PRK00124, PRK00124, YaiI/YqxD family protein.	2.56384e-59
NZ_CP047422.1\|WP_159353106.1\|3734280_3734667_-\|hypothetical-protein	gnl\|CDD\|341046	cd17503, MFS_LmrB_MDR_like, Bacillus subtilis lincomycin resistance protein (LmrB) and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of multidrug resistance (MDR) transporters including Bacillus subtilis lincomycin resistance protein LmrB, and several proteins from Escherichia coli such as the putative MDR transporters EmrB, MdtD, and YieQ. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. For example, MMR confers resistance to the epoxide antibiotic methylenomycin. This subfamily belongs to the Methylenomycin A resistance protein (also called MMR peptide) and similar multidrug resistance (MDR) transporters (MMR-like MDR transporter) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.69876e-06
NZ_CP047422.1\|WP_159353111.1\|3743905_3745030_+\|S-(hydroxymethyl)glutathione-dehydrogenase/class-III-alcohol-dehydrogenase	gnl\|CDD\|176260	cd08300, alcohol_DH_class_III, class III alcohol dehydrogenases. Members identified as glutathione-dependent formaldehyde dehydrogenase(FDH), a member of the zinc dependent/medium chain alcohol dehydrogenase family. FDH converts formaldehyde and NAD(P) to formate and NAD(P)H. The initial step in this process the spontaneous formation of a S-(hydroxymethyl)glutathione adduct from formaldehyde and glutathione, followed by FDH-mediated oxidation (and detoxification) of the adduct to S-formylglutathione. MDH family uses NAD(H) as a cofactor in the interconversion of alcohols and aldehydes or ketones. Like many zinc-dependent alcohol dehydrogenases (ADH) of the medium chain alcohol dehydrogenase/reductase family (MDR), these FDHs form dimers, with 4 zinc ions per dimer. The medium chain alcohol dehydrogenase family (MDR) have a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which have a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding.	0
NZ_CP047422.1\|WP_159353104.1\|3727625_3728819_-\|ISL3-family-transposase	gnl\|CDD\|376574	pfam01610, DDE_Tnp_ISL3, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS1165.	2.4405e-80
NZ_CP047422.1\|WP_071237479.1\|3745040_3745877_+\|S-formylglutathione-hydrolase	gnl\|CDD\|131868	TIGR02821, S-formylglutathione_hydrolase, S-formylglutathione hydrolase. This model describes a protein family from bacteria, yeast, and human, with a conserved critical role in formaldehyde detoxification as S-formylglutathione hydrolase (EC 3.1.2.12). Members in eukaryotes such as the human protein are better known as esterase D (EC 3.1.1.1), an enzyme with broad specificity, although S-formylglutathione hydrolase has now been demonstrated as well. [Cellular processes, Detoxification].	3.20453e-136
NZ_CP047422.1\|WP_159353108.1\|3737550_3738573_+\|IS110-family-transposase	gnl\|CDD\|226077	COG3547, COG3547, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.18181e-43
NZ_CP047422.1\|WP_159353383.1\|3738824_3739997_-\|benzoate/H(+)-symporter-BenE-family-transporter	gnl\|CDD\|281578	pfam03594, BenE, Benzoate membrane transport protein.	1.51728e-132
NZ_CP047422.1\|WP_044734647.1\|3720556_3722509_-\|acetate--CoA-ligase	gnl\|CDD\|234677	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional.	0
NZ_CP047422.1\|WP_159353105.1\|3729030_3732255_+\|protease	gnl\|CDD\|143478	cd07562, Peptidase_S41_TRI, Tricorn protease; serine protease family S41. The tricorn protease (TRI), a member of the S41 peptidase family and named for its tricorn-like shape, exists only in some archaea and eubacteria. It has been shown to act as a carboxypeptidase, involved in the degradation of proteasomal products to preferentially yield di- and tripeptides, with subsequent and final degradations to free amino acid residues by tricorn interacting factors, F1, F2 and F3. Tricorn is a hexameric D3-symmetric protease of 720kD, and can self-associate further into a giant icosahedral capsid structure containing twenty copies of the complex. Each tricorn peptidase monomer consists of five structural domains: a six-bladed beta-propeller and a seven-bladed beta-propeller that limit access to the active site, the two domains (C1 and C2) that carry the active site residues, and a PDZ-like domain (proposed to be important for substrate recognition) between the C1 and C2 domains. The active site tetrad residues are distributed between the C1 and C2 domains, with serine and histidine on C1 and serine and glutamate on C2.	1.47296e-71
NZ_CP047422.1\|WP_025887666.1\|3740126_3740702_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|380339	cd02209, cupin_XRE_C, XRE (Xenobiotic Response Element) family transcriptional regulators, C-terminal cupin domain. This family contains transcriptional regulators containing an N-terminal XRE (Xenobiotic Response Element) family helix-turn-helix (HTH) DNA-binding domain and a C-terminal cupin domain. Included in this family is Escherichia coli transcription factor SutR (YdcN) that plays a regulatory role in sulfur utilization; it regulates a set of genes involved in the generation of sulfate and its reduction, the synthesis of cysteine, the synthesis of enzymes containing Fe-S as cofactors, and the modification of tRNA with use of sulfur-containing substrates. This family belongs to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	4.28343e-20
NZ_CP047422.1\|WP_159353103.1\|3726607_3727384_-\|phosphatase-PAP2-family-protein	gnl\|CDD\|239490	cd03396, PAP2_like_6, PAP2_like_6 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which mainly contains bacterial proteins, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	6.99345e-42
NZ_CP047422.1\|WP_101059344.1\|3733891_3734302_-\|hypothetical-protein	gnl\|CDD\|226867	COG4460, COG4460, Uncharacterized protein conserved in bacteria [Function unknown].	7.34028e-19
NZ_CP047422.1\|WP_044734646.1\|3723108_3726537_+\|sensor-histidine-kinase	gnl\|CDD\|223664	COG0591, PutP, Na+/proline symporter [Amino acid transport and metabolism / General function prediction only].	1.01156e-64
NZ_CP047422.1\|WP_028781419.1\|3742879_3743773_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176159	cd08470, PBP2_CrgA_like_1, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding domain. This CD represents the substrate binding domain of an uncharacterized LysR-type transcriptional regulator (LTTR) CrgA-like 1. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.10484e-107

>NZ_CP047422.1|WP_159353107.1|3736211_3737186_-|transposase
MPRPRYAQVSLEDTPFYHCISRCVRRAFLCGVDDYSGKSYGHRRDWVESRLLELVTVFSIDLCAYAVMSNHLHLVLRVDLKTATEWTLEQVLQRWHLLYSGTLLSLRFLRGETLSDIEYLTLQQTTEVYRQRLMDISWFMRALNEPIARQANREDGCSGRFWEGRFKSQALLDDAAVLACMAYVDLNPIRAGIAKTPEDSDYTSIQRRIQAAMQGKNTPELLPFVGNERLNMPQGLHFEAKDYLQLVDDTGRIIRHDKRGQITAGTTTILNRLNIPVGNWLKLTTDFSRLFKGPVGTLESLTDYCIHLQRRRRQGAANCQKLFS
>NZ_CP047422.1|WP_159353106.1|3734280_3734667_-|hypothetical-protein
MHSLFTMGVLIIAFHFNIQLLIIAYLLMGLGGGVSANTAQTTAMIDFDEATLTKASAVWNLNRQISFSLGCAFFTLLFNVLQHYTNDTSAYQLTFLLAAFIGIPPLFIIKKLNRKPNEDKSSCYPKRN
>NZ_CP047422.1|WP_101059344.1|3733891_3734302_-|hypothetical-protein
MLPEKELVEVAHRSVLDLHVWIQDVFTGSAEQEASLEKLINSFCPSFTMVTTSGSVADKSQVDVLFRKNKGTRPSLSILIEQCETLLINADSVVLSYREIHQEAEKNSSRSSVVIIDIKDGKPLWRYLQETAQSRS
>NZ_CP047422.1|WP_045284110.1|3732780_3733368_+|hypothetical-protein
MESWEKLTNPEILRNSLMSASVYLSAYEMCRDFIVSKPKGFFTDYCGEDGEKLSDEYDEDVLCHSKSPLKASLKWFENLGAIDSNDIALFDAAREHRNDIAHNLPNYISDPDFSVNQEIFNSLLTVTHKIGVYWVVNFEMALNPDYSGHEINESEIKIGTLLMIDMTMQIAFGEGPEEGYYYKEMKRRTAPNKPV
>NZ_CP047422.1|WP_159353105.1|3729030_3732255_+|protease
MKLNKLFWLTALALGSPNLLAAEAKLLREPDLRGDTLVFSYAKDIWKVSLKGGEAVRLTSFQGQEMQPKLSPDGKWVAFTGDYEGNQDIYLLPIAGGEPKRLTFHPDVDQLVGWSPDSKSVLLRSGRANAPRGWQQLFTLSIEGGNPKPLPMNRAFDGSFSADGKQLVYRRAGLWDPGWRNYRGGQNQPLRLISLDSLEEKDLPWDNTQDLEPQWHGDYIYFLSNRSQVTNIFRVAVKGGEPEQVTHYRDADVKGFTMDNDTLVYEYRGELVKKSLANTNSNDKDEALAISLHADFPWVRPRFEEVEKQIESAAISPTGKRALFVARGDVFTVPVEHGDARNLTESSDSREVGAAWSNGGKQLAWFSDKSGEYRLVIADQLGKPQQEIKLAEKGFYSGLIWSPDDKQLVFSDQRQQLWLADLSKGKAQVIDSQPVVNPDWEMAPSWSPDSRYLAYSKQDDSFFRSLYLFDTRNNQSNRITQGMADVRYPVWDSAGDKLYFAASTDYGPHAAWLDMTSVAFTPTYGLYAMLLNTRTEAPMLPRSDEEEGSGTEEEAKGSDAPPAVRIDLNGIAQRVLPLGESGKIHSLSAGKPGELFYMQDLDETTELRKYSTEERKADTLADDVDEYHLSHDGESLLVKIGDNWQQFASAAPMGDDAKTLKVKLTARIDPKAEWQQIFREAWRFQRDYFYVSNLHGADWDAVYKEFQPLVAHVRHGADMTYLLDNMGAETSVGHSFTNDGDLPEIADNRTGLLGADVEATDKGYRFSRIYRGENWYPADQGSAPLALYPLVKEGQYLLAVNGKPLDNKANFYQAFQGTLGKQTRLSISPDGSDKKAFEVTVVPTASEQALRRNAWVEDNRKRVDEASGGKLAYVWVPDTGENGFSYFNRYFFAQNQRQGVIIDERFNHGGYIAEYIIDVLRRERNGYFNNQMAGDHPMTSPGSGIWGAKVMLINEVSGSGGDMLPYMFRYYQVGKLVGKRTWGGLVGIWGVPSLMDGGHITAPRSGFFSIDGQWRVENEGVAPDVEVEQWTKDTAKGIDPQLEKAIAIALDELKSVAPVKLPQPADPVRVPQVK
>NZ_CP047422.1|WP_159353104.1|3727625_3728819_-|ISL3-family-transposase
MSNITFPIALWEGFEAVHTEQNQQTLIIHLKPIDNGHCACGKPAKAVHDASLRSVSERTIMAFQVQLRLPVRRILCPDCGIVREHISWLKPYARQTTLLIEHVEALLKLLPIKHISQLLGLHWHTIKTIDKRRLAREVTEPDWSRVKRLVMDEFALFKGHRYATVVADADTHQVLWIGEGRSREAIRPFFVKLGQYCQQIEAVAMDMNTAFDLEVQKHCPQAKVVYDLFHVVAKYGREVIDRVRVDQANQLKHDKPARKRVKRGRWVLLKNRDNLTDKQAGYLNELLESNKSLMTVYLLREQLKEMWYCTDEAEATAQWNLWWQQVRESGIRPLLQFGQRLKNYLHGIVASAVHPLHTCRLEGMNNKIKLLKRMGYGYRDTEYFFLKVREAFPGDPR
>NZ_CP047422.1|WP_159353103.1|3726607_3727384_-|phosphatase-PAP2-family-protein
MPIASHPLSFQHWFKHHLLLPLSVGLGVLILLHITNADLLLAQWMLAFEGTDTAWPWRHAFVADKLLHTGGRDLVVLAAVVLLSTLVLSSFKASMKRWRRPLLMLFISALATVLLVRIGKSMTNVACPWDLSLFGGQQPYLPFPMSLSVDTELGQCFPGGHSSGAFAWVGLYYLALVLKPKWRFKLLGAVLLIGAVFSLCQEFRGAHFLSHDIASALIGWTMATLSYGLAYRPWRAAGYAGVLAQAQTLTQTQTEVTR
>NZ_CP047422.1|WP_044734646.1|3723108_3726537_+|sensor-histidine-kinase
MNLTLFVAVIAVCYVCLLFLLAWGAERWFSGVTRRLQKWIYALSLAVYCSSWSFLGTVGQSANDFWSYLHIFIGPIIIFTLGFGMLRKMVVVSKAQNITSVADFIAARYGKSQPLAVIITLIALFGIMPYIALQLKAMVFSLSLFQSPDDPLDGAKVALIIAVLLAIFAILFGTRKLDATEHNPGMMLAIAFESLVKLAAFVLVGGIVVFGVFGGFGDLWSQASAKGVIVNPNLRLEALMPELIVGMAAFLCMPRQFHVMVVEAEGEQTLSKARWLFPLYIGLFGLFVGPLALAGKVLLGDSVSADTYVINLPLALDAPWLAIVALLGTLSAATGMVIVAVVTISVMISNEWLVPVLLRTGQIRRKNFSQFSQQLLYARRLSIALILAFGYFSYLSFESSDSLSNLGMLSFGAFAQLAPALVGGLYWKHGNRAGVFLGMAAGFGLWGFLLLKGSGAWEGVLAGQFELLKALKPNVNDTLLALGANLIGYIGGSIWLRAGLVERIQASAFVTPGELKNTGNRKTGPISQQDLLILASRFVSPTRAYESFSRFSADAVRSDSWHKTASPELIAHTEHMLAGVLGASSASLVMDSVLQGRDLALDEVFSLVDEASSKIILSQDMLRAAIEHAYEGMSVVDKDLNLVAWNYRYVELYDYPEDFLQPGMPISEVIRFNASRGYCGPGDVNEHVERRVQHMRNGTAHSSERRRRDGKVIKIQGNPMPDGGFVMTFTDITQYREQQQALEQVNETLEARVKERTYELALLNSKLLEAKAQEEMANASKSRFLAAVGHDLMQPLNAARLFTASLSQYPGLDREGRLTLSHVNSSLKTAGELLTDLLDISKLDSGMVEVKRRDFAISEVLNALAVEFEAMAKDCQIRFAMMPCSLTVNSDPSLLRRVLQNFLTNAYRYAKGGRVLMGCRRRGSELEVQVLDTGCGIEAGQLREIFHEFKRLDNPHSNSVNGLGLGLAIADRISKVLEHDIRVSSVQGKGSVFAIRVPLGATVSVPQPKAISSVLQPLAGVKVLCIDNEEAILAGLESLLSRWQCEVICARDLSDARIKLGLKGVAPDIMLADYHLDKGQNGVDAMDELRALYGQHLPGILITANTRKDLVEDVERRGYHYMAKMIKPAALRALISSLVKKA
>NZ_CP047422.1|WP_044734647.1|3720556_3722509_-|acetate--CoA-ligase
MSTQSLYKVPAAIAANALVNDEKYKKMYQESVVNPEGFWREHGKRIDWIKPYTKVKKTSFDDHNLSINWFYDGTLNASANCLDRHLEKLGDQTAIIWEGDDAKDQRTLSYSQLHTEVCKFANALKSQGVRRGDVVTMYMPMVPEAAIAMLACARIGAVHSVVFGGFSPDSIASRIIDGRSKVILTADEGLRGGRAIPLKRNIDEALAHPDVTTVEKVIVLKRTGNDINWVDGRDVWWESLTETASEHCEVEEMGAEDPLFLLYTSGSTGNPKGVLHTTGGYMVYASMTHEYVFDYKQGEVYWCTADVGWITGHSYMIYGPLANGATVLIHEGVPNYPSPARLGEMIDRHQVNILYTAPTLIRALMAEGKEQFDQFDGSSLRIMGSVGEPINPEAWRWYHEVIGHEHCPIVDTWWQTETGGILISPLPGATDTKPGSATRPFFGVQPALVDNMGNILEGATEGNLVMLDSWPGQMRTVYGDHERFALTYFKTFRGMYFTGDGARRDEDGYYWITGRVDDVINVSGHRLGTAEIESALVAHDLVAEAAVVGYPHDIKGQGIYAYVTLTKGIEATEELRQQLRQWVRKEIGALATPDLIQFAGGLPKTRSGKIMRRFLRKIAANEITNLGDASTLADPAVIDTLIESRLNRTE
>NZ_CP047422.1|WP_159353102.1|3718937_3720107_+|porin
MKQARLTGVCAATLLALGGLGTAQASVLEKTDVQFGGYLKADIMFSDYSNGAPDSNNVSRQFYVPGAIYGVGGNGNQVTDFQARETRFNFKTVTDLDGHTLTGFIELDFMTHTDGDERVSNSYSPRIRHAFISYDNWTIGQTWTTFMNPGALPENLDFVGATEGTPFARQAQLRYSNGGFQIAIENPETTITPYGGGSRITSGNGVMPDLIARYNFKTSGGASFSVMGMLRQLELETRIANQDIDSTELGYGASVAGIIPVGRDDIRFTATYGEGLGRYVALNFANGAVLDNNNDLQAIESYSGFVSYRHWWNEQWRSSFTLSAFSADNDVSLTGSSANKESYSGYINLLYSPVKALTFGVEYMYAKNERENGTDGELNRVTFSAKYVL
>NZ_CP047422.1|WP_159353108.1|3737550_3738573_+|IS110-family-transposase
MEQIIGIDLAKRVFQVNIVSAQGEKKANKMITREKLTAFIVQQPPSRIVMEACGSANYWSRQFRQYGHEVKQISPQYVAPFRMGSKNDKNDAAAIVEADSRPGMRYVPEKSIEQQDIQCLHRVRQRLMKNKTALINQIRGLGLEYGIAIPEGAHKIMAHLPEHLEDAENELTTLSRELFHEMLQELQDNQQRIKTLDLRLALISQQNEDTLRLKSIPGIGPLGASALTVALGDSADFQNGRHFASYLGLVPKDHSSGGKVRLLGITKRGDGYLRGLLIHGARSVVYRVINLPEERCGGLQRWLKGIIARSGVNKAVVALANKNARIAWALINQKTEYIVK
>NZ_CP047422.1|WP_159353383.1|3738824_3739997_-|benzoate/H(+)-symporter-BenE-family-transporter
MWREALGLSKISAGFIAVLVGYSSSAVIILQAADAVGATSAQMSSWLWALGVGMGLTSIGLSLYYKNPVLTAWSTPGATLMVTSLTGLSIHEAVGAFLISSLLITLCGLAGWMDKLIRIMPQSVASAMLAGILLQFGLGLFQAMQTQLSLILLMLLVFIVLKPWAPRYIMLLTLVAGIGMSYQLDLLKLDKLELQFAAPVWIAPAFSIANVVGVALPLFVVTMASQNMPGVAALHGHGYRPPISPLITVTGLMGVLFAPFGGFAFNLSAITAAICMGKEADPNPASRYWAAVWGGVFYLITGLLGATVVGLFAAFPKELVLAIAGLALLGTIGNSLTAALADNDEHEVVVITFLVTASGVSVLGIGSAFWGLLLGFLMHYWHKHRALTTT
>NZ_CP047422.1|WP_025887666.1|3740126_3740702_+|helix-turn-helix-domain-containing-protein
MQTINSYLAATLKQLRSQKGWSLDKAALETGVSKAMIGQIERGESSPTIATLWKIASGFNTSLSTFLEPMPESQGAVFRNADALRQKPATDGMLVASLFPFEPRFGFEMFELTLLPHYERLSEPHEAGVTEHVIVLSGTMEVLVDGQWQPLQQGEAVRFAADKPHGYRNLRDQPVVFHDLIHYHREAPATE
>NZ_CP047422.1|WP_159353109.1|3740878_3741253_+|hypothetical-protein
MKRQTWASNRAVAMVCLAELPSDMDTYISQLRNKVAFKVGFLPLVWGLYLQVIIFCPKISEEALSPADYVAKLDNQWAIVQSVFLVDTVNKVFKEGRTWGQFLSSSYQDAISSELQAFYTKSDR
>NZ_CP047422.1|WP_159353110.1|3741267_3742053_+|hypothetical-protein
MIPNLDIAGDWRAYLEARASGIKSLWKKELAAVLERIDALEGETLASYLESLCELALCRSQPDRNAPQAASEEVSQLELDSPSLALPLAHPGLLPKLQAFWLARFDEPKVKLWLYCAYGLQDTYIKMRPLLGAAEGIDNPSPEILLQQILADSGVTDFLRQQAALHLARSLLESLDFALHEVPYCLCIRADICWQMLDELDELATILPVVPLSRFNLSGEAYRRALTLWCNYCDYTEEQGARGHEPLEYDDWCAKLAEEHD
>NZ_CP047422.1|WP_144166661.1|3742234_3742705_+|YaiI/YqxD-family-protein
MAQIWVDADACPVVIREMLVRAAARTGINVTFVANQALRIIGAASVKTLQVPKGFDVADNEIVRLCQAGDLVISNDIPLAAEVIDKGAKALNSRGELLNRDNVRARLNMRDFLDTLRASGIDTGGSPKLSQADRQTFANELDKYLLHWQRAKTRQG
>NZ_CP047422.1|WP_028781419.1|3742879_3743773_-|LysR-family-transcriptional-regulator
MNHWEGISEFIAVAESQSFTRAAERLNLSVAQISRQIAALEKRLASKLFYRTTRKVSLSEEGQLYYRHCRLLQDGIEEAERALGSLKQTPQGLLRVTAPVTYGEQFILPLLNDFLCLHPKLDLQLDLNNKTLDLIDGGYDLAIRLGKLADSSLMARRLGSRRNYVCASPEYLANHGVPHTLGELHRHQCLLGNHPYWRFIEQGQERQWRLSGRLVCNSGPGLLDAARKGLGLVQLPDYYVGEDLASGALVSVLEAYQAAPEGIWALYPQNRHLSPKVSLLLDFLQQALPEAPDLGKS
>NZ_CP047422.1|WP_159353111.1|3743905_3745030_+|S-(hydroxymethyl)glutathione-dehydrogenase/class-III-alcohol-dehydrogenase
MTDKFIKSRAAVAWAAGEPLKMEEVDVMLPKAGEVLVRIVASGVCHTDAFTLSGDDPEGVFPAILGHEGGGIVEMVGEGVTSVAVGDHVIPLYTPECGECKFCRSGKTNLCQKIRETQGKGLMPDGTTRFFKDGKPIFHYMGCSTFSEYTVLPEISLAKVNKSAPLEEICLLGCGVTTGMGAVMNTAKVEEGATVAIFGLGGIGLSAVIGAVMAKAGRIIGIDVNESKFELAKKLGATECINPKDYDKPIQQVIVDLTDGGVDYSFECIGNVDVMRSALECCHKGWGESVIIGVAGAGREISTRPFQLVTGRVWKGSAFGGVKGRSQLPGIVEDYLAGKFKLDDFITHTMGLEDINEAFELMHEGKSIRSVIHF
>NZ_CP047422.1|WP_071237479.1|3745040_3745877_+|S-formylglutathione-hydrolase
MENISNNRSFGGWHKQYRHHSSSLNCEMRFAIYLPEQANSQKVPVLYWLSGLTCTDENFMQKAGAQRLASQLGLAIVCPDTSPRGEGVADADDAAYDLGLGAGFYVNATQAPWSSHYRMYDYVVDELPALIEQHFPVSGKRAIAGHSMGGHGALMIALKNPGRYLSASAFAPISHPSQCPWGQKAFAAYLGSDREAWKAYDTVELIKSGAKGLPMRVDQGESDLFLAEQLLPQALQAAATDAGIALSFHSHPGYDHSYYFIASFIDEQLKFHASHLGL
>NZ_CP047422.1|WP_025011191.1|3746040_3746502_+|hypothetical-protein
MKIGRWQTPFEQGDLFITGLFWGGDFMLQLPGGKRYQIKNTPHPGVDLSLELFHLPSEGRYRLHYHSVTAFRMLDEHGLLELWQALSELGDEQGYNSRLIKDHAWSQESPISFFHGHSEGWSHLICTGDECVEVLCPGAPEIIYLGKCAAMED

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

239193 : 246511

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025009431.1\|239193_239670_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.1e-31	48.3
WP_028779054.1\|239789_240896_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	3.9e-64	37.8
WP_107005693.1\|240977_241634_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	6.6e-27	33.7
WP_159352321.1\|241634_242759_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A1V0SE20	Indivirus	3.1e-48	34.2
WP_025009434.1\|242799_243252_-	transcriptional regulator NrdR	NA	NA	NA	NA
WP_025009435.1\|243361_244615_-	serine hydroxymethyltransferase	A0A219Y950	Aeromonas_phage	3.2e-102	54.1
WP_025887609.1\|244843_246511_+	energy-dependent translational throttle protein EttA	A0A1B0RXA0	Streptococcus_phage	3.0e-39	28.1

DBSCAN-SWA_2

711729 : 750866

Ralstonia_phage(50.0%)

plate,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025886895.1\|711729_712812_-\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
WP_159352422.1\|712815_713403_-	hypothetical protein	NA	NA	NA	NA
WP_025009963.1\|713494_714076_-	hypothetical protein	NA	NA	NA	NA
WP_025886893.1\|714176_714461_-	type VI secretion system PAAR protein	NA	NA	NA	NA
WP_159352423.1\|714483_715593_-	DUF2931 family protein	NA	NA	NA	NA
WP_159352424.1\|715594_717676_-	hypothetical protein	NA	NA	NA	NA
WP_159352425.1\|717672_718536_-	DUF4123 domain-containing protein	NA	NA	NA	NA
WP_107006115.1\|718581_719139_-	hypothetical protein	NA	NA	NA	NA
WP_159353332.1\|719138_721796_-	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	2.6e-29	25.7
WP_025890191.1\|722124_722643_-	Hcp family type VI secretion system effector	NA	NA	NA	NA
WP_144162365.1\|723083_724158_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.8e-56	45.1
WP_025890157.1\|724255_725041_-	hypothetical protein	NA	NA	NA	NA
WP_144133454.1\|725044_728491_-	hypothetical protein	NA	NA	NA	NA
WP_159352426.1\|728477_729437_-	DUF4123 domain-containing protein	NA	NA	NA	NA
WP_159352427.1\|729423_731490_-	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	2.0e-29	25.7
WP_025890191.1\|731797_732316_-	Hcp family type VI secretion system effector	NA	NA	NA	NA
WP_159352428.1\|732552_733827_-	hypothetical protein	NA	NA	NA	NA
WP_159352429.1\|733902_737463_-	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_159352430.1\|737479_738880_-	type VI secretion system protein TssA	NA	NA	NA	NA
WP_159352431.1\|738883_739537_-	type VI secretion system-associated protein TagO	NA	NA	NA	NA
WP_159352432.1\|739536_741093_-	AAA domain-containing protein	NA	NA	NA	NA
WP_159352433.1\|741092_743681_-	type VI secretion system ATPase TssH	H6X3M6	Enterobacteria_phage	6.1e-92	31.8
WP_028781258.1\|743691_744483_-	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_071237773.1\|744486_745818_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_025889986.1\|745820_746351_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_028781259.1\|746350_747679_-	type VI secretion system-associated FHA domain protein TagH	NA	NA	NA	NA
WP_071237775.1\|747694_748705_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_115389194.1\|748668_750435_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_051472870.1\|750437_750866_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA

DBSCAN-SWA_3

2871303 : 2934558

Catovirus(15.38%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_159352912.1\|2871303_2873883_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	1.1e-189	43.3
WP_025011679.1\|2874005_2874506_+	zinc ribbon-containing protein	NA	NA	NA	NA
WP_025011680.1\|2874646_2875300_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_144167850.1\|2875286_2876132_-	SDR family oxidoreductase	A0A0K0KVL6	Prochlorococcus_phage	7.0e-05	26.5
WP_115389898.1\|2876146_2876818_-	iron-containing redox enzyme family protein	NA	NA	NA	NA
WP_159352913.1\|2876817_2878449_-	AMP-binding protein	A0A1V0SBX8	Catovirus	4.5e-16	25.6
WP_159352914.1\|2878445_2879165_-	hypothetical protein	NA	NA	NA	NA
WP_159352915.1\|2879277_2880831_-	apolipoprotein N-acyltransferase	NA	NA	NA	NA
WP_025011682.1\|2880827_2881709_-	CNNM family magnesium/cobalt transport protein CorC	NA	NA	NA	NA
WP_028781579.1\|2881741_2882203_-	rRNA maturation RNase YbeY	NA	NA	NA	NA
WP_025011683.1\|2882192_2883239_-	PhoH family protein	A0A0S0MVD6	Pseudomonas_phage	7.8e-46	46.1
WP_025011684.1\|2883368_2884793_-\|tRNA	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	NA	NA	NA	NA
WP_045283891.1\|2884890_2885214_-	hypothetical protein	NA	NA	NA	NA
WP_144167843.1\|2885366_2886635_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_025011686.1\|2886827_2887415_+\|tRNA	aminoacyl-tRNA hydrolase	NA	NA	NA	NA
WP_025011687.1\|2887500_2888592_+	redox-regulated ATPase YchF	NA	NA	NA	NA
WP_071237171.1\|2889691_2890105_-	hypothetical protein	NA	NA	NA	NA
WP_109248065.1\|2890101_2890560_-	hypothetical protein	NA	NA	NA	NA
WP_159352916.1\|2890654_2891629_-	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	A0A1X7QHI1	Faustovirus	2.0e-19	26.9
WP_071238787.1\|2891766_2892684_-\|transposase	IS5 family transposase	A0A1V0E8E1	Vibrio_phage	1.0e-97	58.0
WP_144216078.1\|2892962_2893493_-	DUF1768 domain-containing protein	A0A1S6UAJ7	Serratia_phage	1.4e-38	48.4
WP_159353364.1\|2895330_2895627_+	hypothetical protein	NA	NA	NA	NA
WP_159352917.1\|2896219_2897194_-\|transposase	transposase	NA	NA	NA	NA
WP_028779717.1\|2897781_2898729_-	ribose-phosphate pyrophosphokinase	A0A2K9L2G2	Tupanvirus	1.9e-43	38.2
WP_109248761.1\|2898808_2899687_-	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase	NA	NA	NA	NA
WP_159352918.1\|2899683_2900355_-	outer membrane lipoprotein LolB	NA	NA	NA	NA
WP_159352919.1\|2900593_2901844_+\|tRNA	glutamyl-tRNA reductase	NA	NA	NA	NA
WP_025011691.1\|2901858_2902944_+	peptide chain release factor 1	W8EDB3	Pseudomonas_phage	4.3e-07	39.7
WP_159352920.1\|2902955_2903801_+	peptide chain release factor N(5)-glutamine methyltransferase	NA	NA	NA	NA
WP_025889918.1\|2903957_2904353_+	SirB2 family protein	NA	NA	NA	NA
WP_096140857.1\|2904352_2905144_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_028779724.1\|2905253_2906495_+	DUF819 family protein	NA	NA	NA	NA
WP_025011695.1\|2906539_2907388_+	3-deoxy-8-phosphooctulonate synthase	E3T537	Cafeteria_roenbergensis_virus	2.9e-51	43.1
WP_159353365.1\|2907374_2907857_+	EamA family transporter	NA	NA	NA	NA
WP_044734998.1\|2907858_2908644_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_159352921.1\|2908729_2910499_-	flavocytochrome c	A0A2P0ZL82	Lactobacillus_phage	9.1e-55	32.6
WP_071237152.1\|2910896_2912018_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_159352922.1\|2912049_2913048_+	porin	NA	NA	NA	NA
WP_025011699.1\|2913160_2914069_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_159352923.1\|2914065_2915277_+	DUF819 family protein	NA	NA	NA	NA
WP_159352924.1\|2915262_2916180_-	2-dehydropantoate 2-reductase	NA	NA	NA	NA
WP_159352925.1\|2916185_2916545_-	VanZ family protein	NA	NA	NA	NA
WP_062793931.1\|2916690_2917176_+	YajQ family cyclic di-GMP-binding protein	NA	NA	NA	NA
WP_159352926.1\|2917172_2918858_-	MFS transporter	NA	NA	NA	NA
WP_025011704.1\|2919019_2919340_-	hypothetical protein	NA	NA	NA	NA
WP_028779732.1\|2919407_2919992_-	peptidyl-prolyl cis-trans isomerase	A0A1V0S9I2	Catovirus	3.0e-07	29.8
WP_025889928.1\|2920057_2920624_-	hypothetical protein	NA	NA	NA	NA
WP_159352927.1\|2920785_2921370_+	outer membrane beta-barrel protein	NA	NA	NA	NA
WP_159352928.1\|2921497_2922559_+	DUF2804 family protein	NA	NA	NA	NA
WP_025889931.1\|2922580_2923501_+	sterol desaturase family protein	NA	NA	NA	NA
WP_159352929.1\|2923500_2924151_+	glutaredoxin 2	NA	NA	NA	NA
WP_159352930.1\|2924276_2925659_-	DUF3300 domain-containing protein	NA	NA	NA	NA
WP_159352931.1\|2926900_2927137_+	hypothetical protein	NA	NA	NA	NA
WP_159352932.1\|2927318_2929226_+	NTPase	NA	NA	NA	NA
WP_159352933.1\|2929268_2930015_+	hypothetical protein	NA	NA	NA	NA
WP_159353366.1\|2929996_2930149_+	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_071237987.1\|2930143_2931346_-\|transposase	IS4 family transposase	A0A0F7LAS3	uncultured_marine_virus	3.2e-112	49.5
WP_089202937.1\|2931497_2931791_+	hypothetical protein	NA	NA	NA	NA
WP_159352934.1\|2931906_2932884_+\|transposase	transposase	NA	NA	NA	NA
WP_159352935.1\|2933574_2934558_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_4

2959524 : 2966586

Vibrio_phage(33.33%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_144167823.1\|2959524_2959692_+	hypothetical protein	Q7M2A8	Enterobacteria_phage	1.4e-10	54.5
WP_159352941.1\|2959789_2959918_-\|transposase	transposase	NA	NA	NA	NA
WP_037474364.1\|2960033_2960396_-	hypothetical protein	A0A1V0E5P9	Salmonella_phage	3.1e-34	64.8
WP_159352942.1\|2960879_2962727_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.9e-34	32.6
WP_144159533.1\|2962860_2964588_-	DNA primase	A0A1S5RF71	Helicobacter_phage	1.5e-46	33.9
WP_025010513.1\|2964668_2965112_-	GatB/YqeY domain-containing protein	R9TF25	Vibrio_phage	1.7e-05	36.3
WP_006080725.1\|2965118_2965334_-	30S ribosomal protein S21	NA	NA	NA	NA
WP_159352943.1\|2965530_2966586_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	2.4e-111	59.5

DBSCAN-SWA_5

3135355 : 3198692

Synechococcus_phage(20.0%)

tRNA,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_107006186.1\|3135355_3136198_+\|tRNA	tRNA pseudouridine(65) synthase TruC	NA	NA	NA	NA
WP_096142632.1\|3136462_3136639_-	hypothetical protein	NA	NA	NA	NA
WP_028779863.1\|3136766_3137231_+	flavodoxin	NA	NA	NA	NA
WP_045283557.1\|3137182_3138664_+	PTS transporter subunit EIIC	NA	NA	NA	NA
WP_159352973.1\|3138750_3139584_+	formyltetrahydrofolate deformylase	M4QRX9	Synechococcus_phage	3.1e-13	38.7
WP_025010977.1\|3139609_3139975_-	DUF3718 domain-containing protein	NA	NA	NA	NA
WP_071238232.1\|3140232_3141057_-	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	NA	NA	NA	NA
WP_159352974.1\|3141074_3143654_-	bifunctional uridylyltransferase/uridylyl-removing protein GlnD	NA	NA	NA	NA
WP_028779850.1\|3143674_3144478_-	type I methionyl aminopeptidase	NA	NA	NA	NA
WP_025010979.1\|3144895_3145624_+	30S ribosomal protein S2	NA	NA	NA	NA
WP_044734899.1\|3145756_3146608_+	elongation factor Ts	NA	NA	NA	NA
WP_025010980.1\|3146677_3147409_+	UMP kinase	NA	NA	NA	NA
WP_025010981.1\|3147437_3147995_+	ribosome recycling factor	NA	NA	NA	NA
WP_028779852.1\|3148079_3148907_+	di-trans,poly-cis-decaprenylcistransferase	R9W0U9	Flavobacterium_phage	1.7e-19	35.6
WP_044734898.1\|3148927_3149785_+	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_159352975.1\|3149789_3150980_+	1-deoxy-D-xylulose-5-phosphate reductoisomerase	NA	NA	NA	NA
WP_071238229.1\|3150995_3152378_+\|protease	sigma E protease regulator RseP	NA	NA	NA	NA
WP_025887252.1\|3152409_3154893_+	outer membrane protein assembly factor BamA	NA	NA	NA	NA
WP_037466989.1\|3154951_3155449_+	OmpH family outer membrane protein	NA	NA	NA	NA
WP_025010986.1\|3155453_3156479_+	UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase	NA	NA	NA	NA
WP_025010987.1\|3156516_3156978_+	3-hydroxyacyl-ACP dehydratase FabZ	NA	NA	NA	NA
WP_025010988.1\|3156974_3157745_+	acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase	NA	NA	NA	NA
WP_025010989.1\|3157759_3158920_+	lipid-A-disaccharide synthase	NA	NA	NA	NA
WP_109248339.1\|3158916_3159537_+	ribonuclease HII	V5LS49	Emiliania_huxleyi_virus	5.7e-28	41.5
WP_028779861.1\|3159778_3163252_+	DNA polymerase III subunit alpha	A0A0K1Y9G6	Streptomyces_phage	1.5e-194	38.8
WP_159352976.1\|3163251_3164799_+\|tRNA	tRNA lysidine(34) synthetase TilS	NA	NA	NA	NA
WP_159353369.1\|3165089_3165341_-\|transposase	transposase	NA	NA	NA	NA
WP_159352977.1\|3165447_3165966_-	DUF4303 domain-containing protein	NA	NA	NA	NA
WP_159352978.1\|3166072_3168382_-	AAA family ATPase	NA	NA	NA	NA
WP_159352979.1\|3168544_3169045_-	hypothetical protein	NA	NA	NA	NA
WP_071238787.1\|3170481_3171399_+\|transposase	IS5 family transposase	A0A1V0E8E1	Vibrio_phage	1.0e-97	58.0
WP_159353370.1\|3172284_3173169_-	diguanylate cyclase	NA	NA	NA	NA
WP_109248860.1\|3173357_3175304_+	potassium transporter	NA	NA	NA	NA
WP_109248859.1\|3175460_3176399_+	hypothetical protein	NA	NA	NA	NA
WP_025887263.1\|3176406_3177531_-	patatin-like phospholipase family protein	NA	NA	NA	NA
WP_145838998.1\|3177694_3179560_-	1-deoxy-D-xylulose-5-phosphate synthase	NA	NA	NA	NA
WP_159352980.1\|3179581_3180463_-	(2E,6E)-farnesyl diphosphate synthase	NA	NA	NA	NA
WP_159352981.1\|3180463_3180703_-	exodeoxyribonuclease VII small subunit	NA	NA	NA	NA
WP_101054979.1\|3181098_3181866_+	flagellar motor protein PomA	NA	NA	NA	NA
WP_101054981.1\|3181870_3182806_+	flagellar motor protein MotB	NA	NA	NA	NA
WP_159352982.1\|3182967_3184422_+\|tRNA	tRNA 4-thiouridine(8) synthase ThiI	NA	NA	NA	NA
WP_159352983.1\|3184489_3184768_-	hypothetical protein	NA	NA	NA	NA
WP_025012011.1\|3184952_3185864_+	transcriptional regulator GcvA	NA	NA	NA	NA
WP_071476302.1\|3185940_3186576_+	hypothetical protein	NA	NA	NA	NA
WP_159353371.1\|3186618_3187074_+	hypothetical protein	NA	NA	NA	NA
WP_159352984.1\|3187198_3187843_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_025887273.1\|3187845_3188235_+	DUF423 domain-containing protein	NA	NA	NA	NA
WP_107352811.1\|3188604_3189687_+	23S rRNA (cytidine(2498)-2'-O)-methyltransferase RlmM	NA	NA	NA	NA
WP_096142761.1\|3189709_3190018_-	hypothetical protein	NA	NA	NA	NA
WP_159352985.1\|3190284_3191538_+	valine--pyruvate transaminase	NA	NA	NA	NA
WP_028781013.1\|3191895_3192471_-	hypothetical protein	NA	NA	NA	NA
WP_025890172.1\|3192573_3193038_-	hypothetical protein	NA	NA	NA	NA
WP_159352986.1\|3193775_3194753_-\|transposase	transposase	NA	NA	NA	NA
WP_096142758.1\|3195100_3195805_-	hypothetical protein	NA	NA	NA	NA
WP_159352987.1\|3195937_3197065_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_159352988.1\|3197714_3198692_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_6

3247365 : 3258300

uncultured_Mediterranean_phage(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_044734853.1\|3247365_3248112_+	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	1.1e-70	51.8
WP_028781519.1\|3248108_3248744_+	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	7.6e-36	51.2
WP_159353373.1\|3248798_3249710_+	peptidoglycan DD-metalloendopeptidase family protein	NA	NA	NA	NA
WP_025889143.1\|3249788_3250745_+	RNA polymerase sigma factor RpoS	G8CLC7	Synechococcus_phage	3.1e-33	36.3
WP_159353374.1\|3250831_3253399_-	DNA mismatch repair protein MutS	A0A1V0SC35	Catovirus	2.7e-31	23.3
WP_025011663.1\|3253706_3254771_+	recombinase RecA	A0A2D1GPX2	Mycobacterium_phage	3.4e-113	61.6
WP_028781521.1\|3254845_3255214_+	regulatory protein RecX	NA	NA	NA	NA
WP_115390129.1\|3255675_3258300_+\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	1.6e-79	39.2

DBSCAN-SWA_7

3385701 : 3395702

Faustovirus(14.29%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025011490.1\|3385701_3386916_+	IscS subfamily cysteine desulfurase	A0A0H3TPH2	Faustovirus	1.8e-33	32.6
WP_025011491.1\|3386948_3387332_+	Fe-S cluster assembly scaffold IscU	A0A218MKD1	uncultured_virus	5.4e-53	77.4
WP_025011492.1\|3387346_3387670_+	iron-sulfur cluster assembly protein IscA	A0A2H4N7N5	Lake_Baikal_phage	1.2e-21	43.0
WP_025011493.1\|3387693_3388218_+	co-chaperone HscB	NA	NA	NA	NA
WP_159353025.1\|3388301_3390164_+	Fe-S protein assembly chaperone HscA	A0A0N9QXN8	Chrysochromulina_ericina_virus	8.6e-104	39.8
WP_025011494.1\|3390172_3390508_+	ISC system 2Fe-2S type ferredoxin	NA	NA	NA	NA
WP_025011495.1\|3390640_3391540_+	30S ribosomal protein S6--L-glutamate ligase	I3ULC9	Synechococcus_phage	5.5e-40	33.3
WP_025011496.1\|3391621_3391819_+	Fe-S cluster assembly protein IscX	NA	NA	NA	NA
WP_025011497.1\|3392212_3392644_+	nucleoside-diphosphate kinase	L7Y4C4	Megavirus	4.8e-18	40.2
WP_144225224.1\|3393032_3395702_+	TonB-dependent receptor	A0A0P0I887	Acinetobacter_phage	5.9e-82	29.7

DBSCAN-SWA_8

3727625 : 3771352

Ralstonia_virus(11.11%)

tRNA,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_159353104.1\|3727625_3728819_-\|transposase	ISL3 family transposase	A4PE56	Ralstonia_virus	1.9e-112	52.4
WP_159353105.1\|3729030_3732255_+\|protease	protease	NA	NA	NA	NA
WP_045284110.1\|3732780_3733368_+	hypothetical protein	NA	NA	NA	NA
WP_101059344.1\|3733891_3734302_-	hypothetical protein	NA	NA	NA	NA
WP_159353106.1\|3734280_3734667_-	hypothetical protein	NA	NA	NA	NA
WP_159353107.1\|3736211_3737186_-\|transposase	transposase	NA	NA	NA	NA
WP_159353108.1\|3737550_3738573_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_159353383.1\|3738824_3739997_-	benzoate/H(+) symporter BenE family transporter	NA	NA	NA	NA
WP_025887666.1\|3740126_3740702_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_159353109.1\|3740878_3741253_+	hypothetical protein	NA	NA	NA	NA
WP_159353110.1\|3741267_3742053_+	hypothetical protein	NA	NA	NA	NA
WP_144166661.1\|3742234_3742705_+	YaiI/YqxD family protein	NA	NA	NA	NA
WP_028781419.1\|3742879_3743773_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_159353111.1\|3743905_3745030_+	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase	E3SJ82	Synechococcus_phage	3.3e-34	30.2
WP_071237479.1\|3745040_3745877_+	S-formylglutathione hydrolase	NA	NA	NA	NA
WP_025011191.1\|3746040_3746502_+	hypothetical protein	NA	NA	NA	NA
WP_025011190.1\|3746525_3747191_-	response regulator transcription factor	NA	NA	NA	NA
WP_025011189.1\|3747427_3747859_-	acyl-CoA thioesterase	A0A292GK23	Xanthomonas_phage	2.6e-08	39.4
WP_025011188.1\|3748055_3749120_-	3-deoxy-7-phosphoheptulonate synthase	A0A0B5IW14	Pandoravirus	3.3e-84	46.5
WP_025887679.1\|3749362_3750175_-	kinase/pyrophosphorylase	NA	NA	NA	NA
WP_025887681.1\|3750299_3752669_+	phosphoenolpyruvate synthase	A0A1V0SGR7	Hokovirus	5.3e-175	37.2
WP_115390266.1\|3752766_3755811_+	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_025011185.1\|3755879_3756329_+	DUF1285 domain-containing protein	NA	NA	NA	NA
WP_025011184.1\|3756777_3757200_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_025011183.1\|3757228_3757564_-	hypothetical protein	NA	NA	NA	NA
WP_044734628.1\|3757740_3758775_-	Glu/Leu/Phe/Val dehydrogenase	NA	NA	NA	NA
WP_044734627.1\|3759075_3759510_+	DUF4826 family protein	NA	NA	NA	NA
WP_109247914.1\|3759638_3760781_-	cupin domain-containing protein	NA	NA	NA	NA
WP_025887690.1\|3760904_3762275_-	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	4.5e-110	45.7
WP_028781430.1\|3762303_3762921_-	high frequency lysogenization protein HflD	NA	NA	NA	NA
WP_028781431.1\|3762924_3764040_-\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_144166656.1\|3764207_3764660_-	NUDIX domain-containing protein	NA	NA	NA	NA
WP_159353112.1\|3764652_3765498_-	pseudouridine synthase	NA	NA	NA	NA
WP_159353113.1\|3765822_3768048_+	NADP-dependent isocitrate dehydrogenase	NA	NA	NA	NA
WP_025011178.1\|3768147_3768354_-	cold shock domain-containing protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	1.3e-16	59.7
WP_025011177.1\|3768750_3769059_+\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	3.3e-13	41.3
WP_028781435.1\|3769093_3771352_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	1.3e-167	43.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP047421

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP047422

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection