CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP047374	Aeromonas salmonicida subsp. salmonicida strain J409 chromosome, complete genome	8 crisprs	DEDDh,DinG,WYL,csa3,cas3	0	0	24	0
NZ_CP047375	Aeromonas salmonicida subsp. salmonicida strain J409 plasmid p1AsJ409, complete sequence	0 crisprs	NA	0	0	1	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP047374_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047374_1

224820-224915

Orphan

Consensus_repeat	Method
TGCAATGGAGCTGCATATGTGTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP047374_1

>merge|NZ_CP047374|1|224820-224915|CRISPRCasFinder
TGCAATGGAGCTGCATATGTGTGGTTTTAAAGAATATGGAGCCCCTGCTTGGGAGGGGCGAGCCCACTCAATGTGCAATGGAGCTGCATATGTTTG

>NZ_CP047374|1|1|224820-224915|CRISPRCasFinder
TGCAATGGAGCTGCATATGTGTG	GTTTTAAAGAATATGGAGCCCCTGCTTGGGAGGGGCGAGCCCACTCAATG
TGCAATGGAGCTGCATATGTTTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047374.1\|WP_159364559.1\|227335_227977_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225775
NZ_CP047374.1\|WP_159364562.1\|233770_238738_+\|alpha-2-macroglobulin-family-protein	unknown	unknown	gnl\|CDD\|225248
NZ_CP047374.1\|WP_088814366.1\|217829_219233_+\|M48-family-metallopeptidase	unknown	unknown	gnl\|CDD\|227122
NZ_CP047374.1\|WP_159364557.1\|223778_224552_+\|transporter-substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|270421
NZ_CP047374.1\|WP_042468012.1\|219428_219908_-\|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl\|CDD\|239264
NZ_CP047374.1\|WP_042468004.1\|242310_243759_+\|tRNA-4-thiouridine(8)-synthase-ThiI	unknown	unknown	gnl\|CDD\|234932
NZ_CP047374.1\|WP_159364560.1\|228915_231894_-\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|238923
NZ_CP047374.1\|WP_159364961.1\|238796_241100_+\|penicillin-binding-protein-1C	unknown	unknown	gnl\|CDD\|183049
NZ_CP047374.1\|WP_159364558.1\|225652_226345_+\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|226634
NZ_CP047374.1\|WP_005310141.1\|226706_227231_+\|acyloxyacyl-hydrolase	unknown	unknown	gnl\|CDD\|378181
NZ_CP047374.1\|WP_005310119.1\|217416_217650_-\|sulfurtransferase-TusA-family-protein	unknown	unknown	gnl\|CDD\|376492
NZ_CP047374.1\|WP_159364556.1\|220761_221382_-\|DUF479-domain-containing-protein	unknown	unknown	gnl\|CDD\|225666
NZ_CP047374.1\|WP_159364561.1\|231989_233678_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|163244
NZ_CP047374.1\|WP_005310125.1\|219966_220317_+\|arsenate-reductase-(glutaredoxin)	unknown	unknown	gnl\|CDD\|239332
NZ_CP047374.1\|WP_005310145.1\|228064_228850_-\|pyruvate-formate-lyase-1-activating-protein	unknown	unknown	gnl\|CDD\|182994
NZ_CP047374.1\|WP_011898880.1\|241173_242133_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047374.1\|WP_042468015.1\|216320_217391_-\|AI-2E-family-transporter	unknown	unknown	gnl\|CDD\|223701
NZ_CP047374.1\|WP_005310133.1\|222958_223729_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226961
NZ_CP047374.1\|WP_005310127.1\|220313_220709_+\|DUF2069-domain-containing-protein	unknown	unknown	gnl\|CDD\|378269
NZ_CP047374.1\|WP_005310131.1\|221524_222427_-\|lysine-exporter-LysO-family-protein	unknown	unknown	gnl\|CDD\|225287

Protein	Function_ID	Function_description	E-value
NZ_CP047374.1\|WP_159364559.1\|227335_227977_-\|hypothetical-protein	gnl\|CDD\|225775	COG3235, COG3235, Predicted membrane protein [Function unknown].	3.54258e-33
NZ_CP047374.1\|WP_159364562.1\|233770_238738_+\|alpha-2-macroglobulin-family-protein	gnl\|CDD\|225248	COG2373, COG2373, Large extracellular alpha-helical protein [General function prediction only].	0
NZ_CP047374.1\|WP_088814366.1\|217829_219233_+\|M48-family-metallopeptidase	gnl\|CDD\|227122	COG4783, COG4783, Putative Zn-dependent protease, contains TPR repeats [General function prediction only].	2.36194e-145
NZ_CP047374.1\|WP_159364557.1\|223778_224552_+\|transporter-substrate-binding-domain-containing-protein	gnl\|CDD\|270421	cd13703, PBP2_HisJ_LAO, Substrate binding domain of ABC-type histidine- and lysine/arginine/ornithine transporters; the type 2 periplasmic-binding protein fold. This subgroup includes the periplasmic-binding proteins, HisJ and LAO, that serve as initial receptors in the ABC transport of histidine and lysine-arginine-ornithine amino acids. They are belong to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	7.86135e-126
NZ_CP047374.1\|WP_042468012.1\|219428_219908_-\|TlpA-family-protein-disulfide-reductase	gnl\|CDD\|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	1.00934e-24
NZ_CP047374.1\|WP_042468004.1\|242310_243759_+\|tRNA-4-thiouridine(8)-synthase-ThiI	gnl\|CDD\|234932	PRK01269, PRK01269, tRNA s(4)U8 sulfurtransferase; Provisional.	0
NZ_CP047374.1\|WP_159364560.1\|228915_231894_-\|EAL-domain-containing-protein	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	5.24894e-101
NZ_CP047374.1\|WP_159364961.1\|238796_241100_+\|penicillin-binding-protein-1C	gnl\|CDD\|183049	PRK11240, PRK11240, penicillin-binding protein 1C; Provisional.	0
NZ_CP047374.1\|WP_159364558.1\|225652_226345_+\|ABC-transporter-permease-subunit	gnl\|CDD\|226634	COG4160, ArtM, ABC-type arginine/histidine transport system, permease component [Amino acid transport and metabolism].	3.42434e-97
NZ_CP047374.1\|WP_005310141.1\|226706_227231_+\|acyloxyacyl-hydrolase	gnl\|CDD\|378181	pfam09411, PagL, Lipid A 3-O-deacylase (PagL). PagL is an outer membrane protein with lipid A 3-O-deacylase activity. It forms an 8 stranded beta barrel structure.	1.62055e-11
NZ_CP047374.1\|WP_005310119.1\|217416_217650_-\|sulfurtransferase-TusA-family-protein	gnl\|CDD\|376492	pfam01206, TusA, Sulfurtransferase TusA. This family includes the TusA sulfurtransferases.	5.30781e-18
NZ_CP047374.1\|WP_159364556.1\|220761_221382_-\|DUF479-domain-containing-protein	gnl\|CDD\|225666	COG3124, COG3124, Uncharacterized protein conserved in bacteria [Function unknown].	3.5389e-47
NZ_CP047374.1\|WP_159364561.1\|231989_233678_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|163244	TIGR03385, Coenzyme_A_disulfide_reductase, CoA-disulfide reductase. Members of this protein family are CoA-disulfide reductase (EC 1.8.1.14), as characterized in Staphylococcus aureus, Pyrococcus horikoshii, and Borrelia burgdorferi, and inferred in several other species on the basis of high levels of CoA and an absence of glutathione as a protective thiol. [Cellular processes, Detoxification].	1.02674e-159
NZ_CP047374.1\|WP_005310125.1\|219966_220317_+\|arsenate-reductase-(glutaredoxin)	gnl\|CDD\|239332	cd03034, ArsC_ArsC, Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the detoxification of arsenic, using reducing equivalents derived from glutathione (GSH) via glutaredoxin (GRX). ArsC contains a single catalytic cysteine, within a thioredoxin fold, that forms a covalent thiolate-As(V) intermediate, which is reduced by GRX through a mixed GSH-arsenate intermediate. This family of predominantly bacterial enzymes is unrelated to two other families of arsenate reductases which show similarity to low-molecular-weight acid phosphatases and phosphotyrosyl phosphatases.	3.36982e-52
NZ_CP047374.1\|WP_005310145.1\|228064_228850_-\|pyruvate-formate-lyase-1-activating-protein	gnl\|CDD\|182994	PRK11145, pflA, pyruvate formate lyase 1-activating protein.	0
NZ_CP047374.1\|WP_042468015.1\|216320_217391_-\|AI-2E-family-transporter	gnl\|CDD\|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	5.34249e-60
NZ_CP047374.1\|WP_005310133.1\|222958_223729_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|226961	COG4598, HisP, ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism].	2.05006e-161
NZ_CP047374.1\|WP_005310127.1\|220313_220709_+\|DUF2069-domain-containing-protein	gnl\|CDD\|378269	pfam09842, DUF2069, Predicted membrane protein (DUF2069). This domain, found in various prokaryotes, has no known function.	4.09151e-37
NZ_CP047374.1\|WP_005310131.1\|221524_222427_-\|lysine-exporter-LysO-family-protein	gnl\|CDD\|225287	COG2431, COG2431, Predicted membrane protein [Function unknown].	9.8385e-78

>NZ_CP047374.1|WP_159364557.1|223778_224552_+|transporter-substrate-binding-domain-containing-protein
MNKLMLATAIVTALSSGSLMAKEWKEVRIGGEGAYPPFSWTEPSGEVKGFDIDIANALCAEMKVKCTLVKQDWDGIIPALLSRKYDAIIATMDITEERKKKVDFTQKYQHIPARFAAKKGTDVQLDKAFMDGKAVAVQRATSMDTYITDNFPNATIKRYGTADEAYLDLKSGRVDYVLADSAAITDGLLKKEGGDGFEFVGPKLTDPKWFGEGAGIAVRKADKDLKEKFNTAILALRANGKYKEINDKYFEFDVYGE
>NZ_CP047374.1|WP_005310133.1|222958_223729_+|ABC-transporter-ATP-binding-protein
MSDVAALEVRELHKYFGTHEVLKGIDMTAHKGDVISLIGSSGSGKSTFLRCINLLETPSSGTVSLHGELIRMKTNRAGERLAEDVRQVERIRSRLAMVFQSFNLWSHMTIMQNIIEVPIQVLKIPRAEAIAKAEHLLNRVGLWERRDYYPGHLSGGQQQRAAIARALAVDPEVMLFDEPTSALDPELVGEVLGLMRELAEEGRTMLVVTHEMSFARDVSNKVMFLHQGRVEEEGNPKEIFAHPKSERFKQFISSIY
>NZ_CP047374.1|WP_005310131.1|221524_222427_-|lysine-exporter-LysO-family-protein
MLLNVLLILLPLAIGYLIPLSSARLIKLVNQSLGKMVYLILFLMGLGLAYVENLGSNLAVIFKVAGVMLAAITFCNLLALWWLDKRSPPTHEASDAKMPSKRHLLWESLQLCFVVLGGVLLGLLVDLRILPIDKLSEWALMLLLLLIGVQMRNSGMRLRQILLNPWGMKIAFTVIVSSWLGSLLAAQLLGMPFSHGLAISSSFGWYSLSGILVADKLGPVLGSAAFINDLGRELIAILIIPMLMHRHPSAAIGYGGATALDFTLPVIQKSGGIQVVPVAIVSGFILSLLGPILILGFLAI
>NZ_CP047374.1|WP_159364556.1|220761_221382_-|DUF479-domain-containing-protein
MNYLAHLHLAAHTRSSLTGNLLGDFIKGPLPSPLAPEFDEGIWLHRKIDAFTDAHPEHRAAVACFEAPWRRFGGILVDMLYDHWLSVHWPQFCAEPLPRFLQHSYDQLLADHLLLADGLPAALKRMAEQNWIASYRHKEGLGRALNGIGHRLRRPVLLGDALTTLDEMDWHTCELGFLRFYPQLMAFSEQQLAHYRETGGHAGLRP
>NZ_CP047374.1|WP_005310127.1|220313_220709_+|DUF2069-domain-containing-protein
MTTRFARLLTLVGFFGLLGWVILWHLFLSPHPDLNPWLLPVIWTVPLLFPLKGIVQGNPYTHAWGNFVLMPYFLHALTLITTDEGERWLAVVELVFTTLAFVGTIYYARLRGRELGLSIRKKKGELSQEEK
>NZ_CP047374.1|WP_005310125.1|219966_220317_+|arsenate-reductase-(glutaredoxin)
MSETQIYHNPRCSKSRETLALLEQHGIAPDVVLYLEQAPSEDVIRTLLTQLGFADPRQLIRTKEDLYKELGLADQSGDALIRAMHQHPKLIERPIVIKDGKARIGRPPEQVLEILK
>NZ_CP047374.1|WP_042468012.1|219428_219908_-|TlpA-family-protein-disulfide-reductase
MVRVSGRAQEMKRICWMIVAALLTACSPAPEFSNGQGQPVTLAQFAGKPLLVNYFAPWCVPCLRELPLLETLAQEGKIAVVVNSYDPATPAELGALASRHHIRVPLLIADKEAHLPFSLPTGLPTSYLLDGEGRLQATLVGELDGQKIAALKLRAAQFR
>NZ_CP047374.1|WP_088814366.1|217829_219233_+|M48-family-metallopeptidase
MGATFHAQANNQLPDIGTAGVAALPIEQEVRYGNAFMRFARAGLPIIDDPVLSQYIDDLGQRLLTNADGVRFPFTFFLVNDPSINAAAFLGGRVKVHTGLFLYADSESELASVLAHEITHVTQRHIARYMEAQASSSAMTLAGLVGSIALAVINPTAGIAALQTTLGLSMQSAINYTRDNEYEADRIGMKTLYDAGFDPMGMANFFQKLAAEYRYASKPPQMLLTHPLPETRISEARGRANSYGRRNLPPSLDFWLAKVRIQVRYGTETPQALLSYFDSRLQKGDYPLKDAATYGKALALLQLKRTDEADTLMQELATRHPEDLFVVDALTDIDLAKGRSAQAIARLEKFRARMPDNEVVVVNLGNAYLEGGDYKKSIAILDPYARDHEENSLAWNLLSDAYRKAGRMTELHMARAEMLSLRGDYQAAIDELIVARGTTSDKLTLARLEARITELERAKKDLDSLKG
>NZ_CP047374.1|WP_005310119.1|217416_217650_-|sulfurtransferase-TusA-family-protein
MEHLDLTPWRCPEPLIRLKLWLRQATPGQSLSIQLADPGSRQDIPAYLQRQGHTVTLQQGPDNTIFLQLVVGAKQPS
>NZ_CP047374.1|WP_042468015.1|216320_217391_-|AI-2E-family-transporter
MLEVLKRWYQTRFSDPDAVTLFLLLVACFAVLWLFGGLLAPLLVALVMAYLLEWPVSRLQRAGLSRALATSLVLLLFIAVTVMALLGLIPTLVSQGINLAKESPSMLAHAQDYVRTLPEKYPEVIDVTLVETIIDNIRQRILSGGEHLVSASLSSLVNVVAILIYLILVPLMVFFMLKDKQELMGGLRRFLPRNRTLVNRVWVEMNDQIINYIRGKVIEILIVGVATYIPFALMGLRYSALLAVAVGFSVLIPYIGAAAVTVPVAMVALFQWGLTPEFTWLMVAYLVIQALDGNLLVPLLFSEAVNLHPVAIIVAVLVFGGLWGFWGVFFAIPLATLVKAVINAWPKRDDPALPGV
>NZ_CP047374.1|WP_159364558.1|225652_226345_+|ABC-transporter-permease-subunit
MDFSIILKEWPTYWQGLYTTVLLVAASLILGLALAVPMGILRNSRNWLIKGPIWAYIYFFRGTPLLVQLFIIYYGAAQWEWLKNSAAWTLFAEAWFCALLAFTLNTGAYTAEIVRGAVLNMPKGQIEAANAFGMSRWQTLTRIILLNSFRRALPAYSNEVIFMLQGSAVAGIITIVDLTGAARIINSRYYSPFEAFLTAGLLYMLLTFVIVWLFKKWEARWHAHLRPRSL
>NZ_CP047374.1|WP_005310141.1|226706_227231_+|acyloxyacyl-hydrolase
MRANTLLLSGLLASLIASTGAIANDNIVALQLGTPSENEKLSIFTADAKYHHMFWRWGDSGCQFGLGVRGGMLKAGDERTARLGTGARAECLWGNWVVWLPAEVIWLADHEFGHRGNGFKDYGGPFQFVTGIGLGYAITKNWLIGYQYEHMSNANMYEQNPGLDTHTLHIEYRF
>NZ_CP047374.1|WP_159364559.1|227335_227977_-|hypothetical-protein
MSEGQAAALLLWVLLLIFSLRGTLLRTLLNQPLYQHLCLGGAIVLVPLWTLRAGLHEGLEVHFLGLTSLTLLLGWRLALLAPCLTLLVLGYFGVASLADFGWQALIGIALPVATSWLLFLASWAWMPRHLFIYLFVVAFFGGALSISVKMIASALLMGMSGAYPWHTISADYLSIWPLLLFPEALLNGMTMTLLAVYRPHWVNTFFDREYLGR
>NZ_CP047374.1|WP_005310145.1|228064_228850_-|pyruvate-formate-lyase-1-activating-protein
MSVSNQIPAVETSESGVIGRIHSVETCGTVDGPGIRFIVFMQGCLMRCKYCHNRDTWDTQGGREVTVPELMSDITSYRHFMNASGGGVTASGGEAMLQQNFIAELFAACKEKGVHTCLDTNGFVRHYDEQLDKVLDNTDLVLLDIKQINDEKHIPLTHVSNKYTLEFARYLAAKGKTMWIRYVVVPTWSDDDESAEGLGQFIAELGDSVEKVELLPYHELGKHKWDVLGENYDLTGIKPPSKETMDRVQGILAKYHNNVKY
>NZ_CP047374.1|WP_159364560.1|228915_231894_-|EAL-domain-containing-protein
MPPDSCSTGCYQFMSSTALSHLPPASQTPLFFRLDVRSQRLVALTDVMQTPLHWLDEPRSAWPAQLPDALRLPIEQALAKGQGGKLMLRFAGQQWHIALSHEQDAFWLICLQTQRQEPIADLALQLPRLSQMASQQQFVAMLEALKESLGADRLILWHYQANGSLGSEQLTPVFALGAEGLSAIRGDSRYIRALRTRKSLSFSEAAHQPMLSQHYYLANAGVSSRLDGALLEQEKLIGVLSLEYLSATVLSEEMLQLVRHSAQLLGHWQPEPEPIINPVLALPGELTLLTGIAYCRALVNWAVTMSGARIGWVGEYQPRGQELWIIPRCVLEGETFSILKPIQLDPGPAQELFQHGQALYVEDLPLRYPLATQLLALNAKAYVGVPLHGPSGAPMGQLTLLLDTPLADPMPLLDALSSQHERAAIELQRLAADDALRLAEVAFNTHDGLLVMDHQGIILKVNHSFSRITGFGNDEMIGQHIVRLRPTYYGDHLKEDVRRAIDEQEFWMGEERCLHKDGHLFPVRLMVSGVKDELGEFSHYVCSFYDITKEKDAARHIEQLAYYDDLCGLYNRRSLNNIMQCTLQAPNGQWGALLLVDLDNFKSINDSLGHACGDQLLQAVVERLKGLPQDNLVLARIPGDEFALLFTALGQGYVTAKILAEHFARELMGLFRTPFDIEDHKLHCSASVGISLFSSEDQDHLVLMQQADTATHMAKRAGQGNYVFFSEAMAEKEKSKLTINNQLRDALRHHELQLHYQPQYRVDNGSLSGIEALLRWQRSDGTMVPPAEFIPIAEETSLIQDIGYWVMKTACAQYSFWLNRGFAIPHLSVNVSARQFHTAGFVQQVEYILRDTGVPPSRLLLEVTESVVLENRLESIARMRQLKELGILLSIDDFGTGYSSLAYLRDLPADEVKLDRSFIQTLVHSEQDKAIVKAILDLAKVFRFTVTAEGVEDEEQLAILKTLGCQHYQGFLTSRPLTVKALESLLGAAQSG
>NZ_CP047374.1|WP_159364561.1|231989_233678_+|FAD-dependent-oxidoreductase
MKRILIVGGVAGGASAAARARRLSEEAEIVVFERGEFVSFANCGLPYHIGGDIQDRDALLLQTPQSFKRRFNVDVRVFHDVIEIDKAGKTLLVRNLQTGEERREPYDQLLLSPGAAPIRPPFPGIDSPHVYTLRNIPDMDRILAALQHDHPRHVTVVGGGFIGLEMMEALHQRKLEVTLLELSDQVMAPVDKEMANMLHARIREEGIDLRLRTGLAAIESLDVLAEKTAAVASATRSGLRLTLSDGSHLETGLLILAIGVKPETLLAAKAGLELGPRGGIKVDAGMRTSDPFIHAVGDAVEETDFVTGESVLIPLAGPANRQGRIAADNMLGRAETYKKTQGTAICKLFDLAVASTGLNEKRLVQLSLPFEKAYVHPGSHASYYPGAHPVSLKLLFAPDGKIYGAQAIGKDGVDKRIDVLAVAQRAGLTVFDLQDLELTYAPPFGSAKDVINMAGFVASNHLKGDTILCHAAEVQARHPHQQVLDVRNGPELDKLGRIPGALHIPLDELRGRLNELPRDKELLISCQVGLRGHVACRLLSQHGFKVKNLSGGFKTWQMAVMD
>NZ_CP047374.1|WP_159364562.1|233770_238738_+|alpha-2-macroglobulin-family-protein
MCQASRMSYPVAYRAAMAAIQSGMEPMRPFDPRPAAHQCAHAFVSPLRRRWSALLLTGLTGLLLAGCGQDKPAATADQAPAARQVAGVPDTVVQANARQYRDAPALALVFSGPLAPKSNWQTWLSVSEGGKQLQGEWVLAEDGRTLYFPQVAPDKSYKVTLKAGLGPEAQSWTLKTRPLDAGASFAASGMVLPLRQELRLPISAVNVDEVNIDFFRVDAEYLPRFLAEYRPGAGMGNWELEQITSRAKRVFSGRYALELDPNRRETRLINVKEPQLAEAGVYFAVMSPLGNYDWRKETTYFAVSDMGLSARRYRDQLEVFVSALSSADPLKEVQLSLLDEKGNRLLVQQTDLRGHRRFDQVQGARLLLAEQGKHLAVLRLDGAALDLSAFELGTQPWQAQQLYLFSGRDLYRPGERLDSEILLKGQDGQLLPGMAVELEVKQPDGQLLEQKRLLPDSLGAAHYGLRLPDDAPLGRWTITLKTAAGSRFEWPFLVEEFLPERLKLQLGKGPDGELLNPQEALTLPLQGDYLYGAPASATKAKAEVKISRATMPFNQWQEFTLGDVLLTEQARDLEPVTLTLDKQGHGAFSLVDQLASVGTLGPLEVAYRVSLSEPGGRAVNRSRTQYGWPTGSQWPALKADFVADRVEGGKTLPFQILNLDEQGQPVAGEVKVRLVNEYRDYYWHYADGEGWKYEFNSQPYLEQEQTLQLDGKGPTTLSLPLAAGWYRLEVENSQGHQSSLRVEIGSYAWGGGGEQARPDKIAITLDKRAYQAGDKAKVTLVAPRAGKGLLLVEDGDGLRWWQRIELRPEGAGLAEARGEFEIPVSPEWQRHDLHISAQIAAPDSESKPVSQKSVQSLRSVGLVPLALDREARRLPLTLSAPDKAVPLTRLEVAVTSTPNSQGRVVLAAVDRGVLNISDYQPLDPFEIFFGRKRFAQDLFDNYGQVIPPQDGKLARLNYGGDAPALKKGGALESRVEVAALWSGEVSFDESGKAVIPLDLPNFNGELALMALAWNEQQVGQAERAVKVVAPLVAEIGWPRFGARGDETRALVQLRNMSGEDQSLSLTWTLTGGLQARGALPETLALKNGEERWLTLPLTVTGASGVARLQLAASGKDFAVNREWSLPLRSPWPAQTRQRYQMLAPNQQMSFAQSELAGLDPANLQGLLSLSGTPPWDPTGQWQALAQYPYACLEQTLSRAWPYLLTTADERAAWSNNLPNVDKPVSEADLQRALLQRLQRLQLPGGGFGLWDGRSDEEQWLTAYAADYLLTRKEAGDAVPEAMLSQAISRLQSYLGDSQYGERWSSAPEHSRLAYQAYSAFVLARVGKAPLSTLRLIWEQQADHARSGLPLLHLSLALSAMGDEQTAAKALTRALATPRGDDYLADYGSPLRDGALELALLRQHKLAEDRWPELSAKVADTLAHRQWLSTQERLALLRLAQVDPAADWQARVASISGGQAVAGKNSAQIGAPEALAATGVTNEGKGSLYVQRTLVGYPEQAPVRISQGMSVTRSWFNADGKQLDPAKVKVGDFVVVRLNVSSEQTVPDALLVEMLPAGFELENPALGTSIKLEELSIEGKPAWQSEWNDYLKHQEFRDDRYTAALDLSEGGNQQLVYLMRAVTPGRYQVPPTQVEDMYRPELRAVGQDIHEVTISE
>NZ_CP047374.1|WP_159364961.1|238796_241100_+|penicillin-binding-protein-1C
MHQGRLALPGLPRWLRLTGLGMGALILVLLVLDRAFPPPPLDPAYARVVLDMKGRPLRAFADTSGVWRYPVTLEQVSPRYIEALLGYEDRHFWRHPGVNPVAMVRGVWQWLRYGRAVSGGSTLTMQVARLIEPYHRSVPGKLRQMARALQLEWHYDKRTLLTVYLNRAPFGGNLEGVQAASFAYLGKSAAKLTHAEAALLAVLPQAPSRYRPDRHPDRARAARDKVMQRLVKQGAWPDAVWREGRIEPVLARGHFTPMEAPLFARLAADSQPGALVHTTIDGDLQRWLEARVATYIRRFPEQTSAALLLVDNQTIAVRAYVGSAEYGNLRRHGYLDMVQAIRSPGSTLKPFIYGLALDAGLVHSASLLSDAPRLGSDYRPANFTGAFQGPVTLTRALQQSLNVPAVQVLEALGPDTLVNRLDNAGVRLALSDKPNPAIALGAAGVRLEQLVALYSSLTRQGQVAMPVWLAGQQAVSRPLLSPGAAWITWQILSSQGRADQPFASEATGRVNRLAWKTGTSYGYRDSWALGVSGRWTLGVWLGRPDGTPLPGFYGQSAAVPLLLSVYSRLGDNSPLPAQPNTVSEAEICWPLGRRVSATLPEACLQHQSAWLLDEQDPPTLPDPMDWPSPLRQVALTSQGKPTLTRCDDASQSVWRALWPLSLEPWRAPGERRKALLASGCEGEAQEADLQAPIRIVALGEGNLIRSQRYRLQPRVLGGVGKPFWFLNGQRLRWDGDQVLSKAGRYQLVVVDEAGNSDRVEFRLENPS
>NZ_CP047374.1|WP_011898880.1|241173_242133_-|hypothetical-protein
MKTYIYYPGMEVRDELWLKFALLYLERLAFVFTISEKSGLTTLLSTLEQRTDLLAERPEPAFFADITPQLESQLGGLVAPDFARHKVFGNRDLITRWRQSANHDCFCPTQAGLERLHGFCLAHGFASQDEGGIKMARRFANLLSMRLAREWALANEGALITDHDYLDRLLHLLESRYHNRGGQDCFHLEIPLRVPTHLSEISFDELIALRARSGFRQQLAEFHQALDAMLTMLGSGYAEPAALTRFELAQQGLNQLLGPATHSLPLTTLISCSLPAMAMIHQLKASHPASNLIFHPIKKSHFHQRKSQHFFTRLGQVKS
>NZ_CP047374.1|WP_042468004.1|242310_243759_+|tRNA-4-thiouridine(8)-synthase-ThiI
MKFIIKLFPEITIKSKSVRQRFTKMLQGNIRNVLRRFDEDARVRMDWDKLVVSSRNDQFHAQYLETLACIPGIQYFLEVKLSNFTDLHDIFEQTRAVWGDRLKGKTFCVRARRVGKHDFSSLELERYVGGGLNQHCETAGVRLKKPDIQVNLEVENDELYIISAVHHGMGGFPIATQEDVLSLLSGGFDSGVASYQFIKRGCRVHYCFFNLGGAAHEIGVKQVAYYLWSKFGASHKVRFTAIDFEPVVAEILEKVDNGQMGVVLKRMMMRAAGQVADYFQIPALVTGECVGQVSSQTLTNLNVIDRVTDKVILRPLITWDKPDIISEARRIGTLEFAETMPEYCGVISKKPTIKAVLSNIEAEEANFDFAILDKVVSEARYLDIRRIGEETAAEVQEIETTEVLAADEVILDIRSADERDEKPLVVEGRDVLHIPFFKLATAFGDLPKEQTYLLYCDRGVMSKLQALYLKEKGFDNVKVYRP

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Crispr_ID: NZ_CP047374_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047374_2

1750587-1750731

Orphan

Consensus_repeat	Method
GCCCTGGGCACACCGGCCTTGATATTCTTCTGTTTCAGTTCCCAGGCATC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP047374_2

>merge|NZ_CP047374|2|1750587-1750731|CRISPRCasFinder
GCCCTGGGCACACCGGCCTTGATATTCTTCTGTTTCAGTTCCCAGGCATCCTTAATGTGAAGAGGCTGGGGCTTGCATCCAAGTCGGTCCGTTGCGCCCTGGGCACACCGGCCTTGATATTCTTCTGTTTCAGTTCCCAGGCATC

>NZ_CP047374|2|2|1750587-1750731|CRISPRCasFinder
GCCCTGGGCACACCGGCCTTGATATTCTTCTGTTTCAGTTCCCAGGCATC	CTTAATGTGAAGAGGCTGGGGCTTGCATCCAAGTCGGTCCGTTGC
GCCCTGGGCACACCGGCCTTGATATTCTTCTGTTTCAGTTCCCAGGCATC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047374.1\|WP_159364796.1\|1743004_1743955_+\|transaldolase	unknown	unknown	gnl\|CDD\|235381
NZ_CP047374.1\|WP_017412585.1\|1756070_1756940_+\|4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol-kinase	unknown	unknown	gnl\|CDD\|234731
NZ_CP047374.1\|WP_011899080.1\|1746275_1747307_+\|IS630-family-transposase	unknown	unknown	gnl\|CDD\|315923
NZ_CP047374.1\|WP_005316978.1\|1744345_1744894_-\|hemerythrin	unknown	unknown	gnl\|CDD\|226454
NZ_CP047374.1\|WP_005317020.1\|1758353_1760342_+\|bifunctional-metallophosphatase/5'-nucleotidase	unknown	unknown	gnl\|CDD\|277354
NZ_CP047374.1\|WP_005317007.1\|1752021_1752891_-\|peptide-chain-release-factor-N(5)-glutamine-methyltransferase	unknown	unknown	gnl\|CDD\|236467
NZ_CP047374.1\|WP_159364797.1\|1745140_1745809_-\|uracil-DNA-glycosylase	unknown	unknown	gnl\|CDD\|235376
NZ_CP047374.1\|WP_005317016.1\|1755459_1756044_+\|outer-membrane-lipoprotein-LolB	unknown	unknown	gnl\|CDD\|319984
NZ_CP047374.1\|WP_042468530.1\|1749675_1750530_-\|3-deoxy-8-phosphooctulonate-synthase	unknown	unknown	gnl\|CDD\|235363
NZ_CP047374.1\|WP_005316976.1\|1744114_1744297_+\|DUF3545-family-protein	unknown	unknown	gnl\|CDD\|371878
NZ_CP047374.1\|WP_005316999.1\|1747601_1747982_+\|autonomous-glycyl-radical-cofactor-GrcA	unknown	unknown	gnl\|CDD\|213978
NZ_CP047374.1\|WP_042468526.1\|1754082_1755339_-\|glutamyl-tRNA-reductase	unknown	unknown	gnl\|CDD\|234592
NZ_CP047374.1\|WP_005316983.1\|1745840_1746098_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047374.1\|WP_088814343.1\|1741436_1742573_+\|ISAs1-family-transposase	unknown	unknown	gnl\|CDD\|379382
NZ_CP047374.1\|WP_159364798.1\|1748087_1749371_-\|C4-dicarboxylate-transporter-DctA	unknown	unknown	gnl\|CDD\|234968
NZ_CP047374.1\|WP_042468523.1\|1760550_1761192_+\|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl\|CDD\|235457
NZ_CP047374.1\|WP_159364800.1\|1757304_1758252_+\|ribose-phosphate-diphosphokinase	unknown	unknown	gnl\|CDD\|234929
NZ_CP047374.1\|WP_005317005.1\|1751593_1751977_-\|SirB2-family-protein	unknown	unknown	gnl\|CDD\|377264
NZ_CP047374.1\|WP_005317010.1\|1752940_1754029_-\|peptide-chain-release-factor-1	unknown	unknown	gnl\|CDD\|234801
NZ_CP047374.1\|WP_159364799.1\|1750781_1751582_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|225464

Protein	Function_ID	Function_description	E-value
NZ_CP047374.1\|WP_159364796.1\|1743004_1743955_+\|transaldolase	gnl\|CDD\|235381	PRK05269, PRK05269, transaldolase B; Provisional.	0
NZ_CP047374.1\|WP_017412585.1\|1756070_1756940_+\|4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol-kinase	gnl\|CDD\|234731	PRK00343, ipk, 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional.	0
NZ_CP047374.1\|WP_011899080.1\|1746275_1747307_+\|IS630-family-transposase	gnl\|CDD\|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	9.20597e-16
NZ_CP047374.1\|WP_005316978.1\|1744345_1744894_-\|hemerythrin	gnl\|CDD\|226454	COG3945, COG3945, Uncharacterized conserved protein [Function unknown].	3.25318e-17
NZ_CP047374.1\|WP_005317020.1\|1758353_1760342_+\|bifunctional-metallophosphatase/5'-nucleotidase	gnl\|CDD\|277354	cd07409, MPP_CD73_N, CD73 ecto-5'-nucleotidase and related proteins, N-terminal metallophosphatase domain. CD73 is a mammalian ecto-5'-nucleotidase expressed in endothelial cells and lymphocytes that catalyzes the conversion of 5'-AMP to adenosine in the final step of a pathway that generates adenosine from ATP. This pathway also includes a CD39 nucleoside triphosphate dephosphorylase that mediates the dephosphorylation of ATP to ADP and then to 5'-AMP. These enzymes all have an N-terminal metallophosphatase domain and a C-terminal 5'nucleotidase domain. The N-terminal metallophosphatase domain belongs to a large superfamily of distantly related metallophosphatases (MPPs) that includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	5.58119e-79
NZ_CP047374.1\|WP_005317007.1\|1752021_1752891_-\|peptide-chain-release-factor-N(5)-glutamine-methyltransferase	gnl\|CDD\|236467	PRK09328, PRK09328, N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional.	9.92111e-127
NZ_CP047374.1\|WP_159364797.1\|1745140_1745809_-\|uracil-DNA-glycosylase	gnl\|CDD\|235376	PRK05254, PRK05254, uracil-DNA glycosylase; Provisional.	7.35243e-146
NZ_CP047374.1\|WP_005317016.1\|1755459_1756044_+\|outer-membrane-lipoprotein-LolB	gnl\|CDD\|319984	cd16326, LolB, LolB, an outer membrane lipoprotein receptor. This family contains the outer membrane lipoprotein receptor, LolB, which catalyzes the last step of lipoprotein transfer from the inner to the outer membrane. There are five Lol proteins (LolA, LolB, LolC, LolD, and LolE) involved in the sorting and membrane localization of lipoprotein and are highly conserved in Gram-negative bacteria. LolA transports lipoproteins through the periplasm to LolB, which then localizes them to outer membranes; the protruding loop of LolB has been shown to be essential for the localization of lipoproteins in the anchoring of bacterial triacylated proteins to the outer membrane.	6.33028e-56
NZ_CP047374.1\|WP_042468530.1\|1749675_1750530_-\|3-deoxy-8-phosphooctulonate-synthase	gnl\|CDD\|235363	PRK05198, PRK05198, 2-dehydro-3-deoxyphosphooctonate aldolase; Provisional.	0
NZ_CP047374.1\|WP_005316976.1\|1744114_1744297_+\|DUF3545-family-protein	gnl\|CDD\|371878	pfam12065, DUF3545, Protein of unknown function (DUF3545). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 60 to 77 amino acids in length. This protein has two completely conserved residues (R and L) that may be functionally important.	3.33253e-11
NZ_CP047374.1\|WP_005316999.1\|1747601_1747982_+\|autonomous-glycyl-radical-cofactor-GrcA	gnl\|CDD\|213978	TIGR04365, Autonomous_glycyl_radical_cofactor, autonomous glycyl radical cofactor GrcA. This small protein, previously designated YfiD in E. coli, is closely homologous to pyruvate formate_lyase (PFL) in a region surrounding the stable glycyl radical that is prepared by the action of pyruvate formate-lyase activase, a radical SAM enzyme. When damage at the site of this radical breaks the main chain of PFL, this protein acts as a spare part that reintroduces the needed stable glycyl radical. Cutoffs for this model are set to exclude a set of closely related phage proteins that appear to have a corresponding function.	2.14422e-82
NZ_CP047374.1\|WP_042468526.1\|1754082_1755339_-\|glutamyl-tRNA-reductase	gnl\|CDD\|234592	PRK00045, hemA, glutamyl-tRNA reductase; Reviewed.	0
NZ_CP047374.1\|WP_088814343.1\|1741436_1742573_+\|ISAs1-family-transposase	gnl\|CDD\|379382	pfam13808, DDE_Tnp_1_assoc, DDE_Tnp_1-associated. This domain is frequently found N-terminal to the transposase, IS family DDE_Tnp_1, pfam01609 and its relatives.	7.38734e-32
NZ_CP047374.1\|WP_159364798.1\|1748087_1749371_-\|C4-dicarboxylate-transporter-DctA	gnl\|CDD\|234968	PRK01663, PRK01663, C4-dicarboxylate transporter DctA; Reviewed.	0
NZ_CP047374.1\|WP_042468523.1\|1760550_1761192_+\|aminoacyl-tRNA-hydrolase	gnl\|CDD\|235457	PRK05426, PRK05426, peptidyl-tRNA hydrolase; Provisional.	3.89654e-107
NZ_CP047374.1\|WP_159364800.1\|1757304_1758252_+\|ribose-phosphate-diphosphokinase	gnl\|CDD\|234929	PRK01259, PRK01259, ribose-phosphate diphosphokinase.	0
NZ_CP047374.1\|WP_005317005.1\|1751593_1751977_-\|SirB2-family-protein	gnl\|CDD\|377264	pfam04247, SirB, Invasion gene expression up-regulator, SirB. SirB up-regulates Salmonella typhimurium invasion gene transcription. It is, however, not essential for the expression of these genes. Its function is unknown.	3.44023e-23
NZ_CP047374.1\|WP_005317010.1\|1752940_1754029_-\|peptide-chain-release-factor-1	gnl\|CDD\|234801	PRK00591, prfA, peptide chain release factor 1; Validated.	0
NZ_CP047374.1\|WP_159364799.1\|1750781_1751582_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|225464	COG2912, COG2912, Uncharacterized conserved protein [Function unknown].	1.30119e-58

>NZ_CP047374.1|WP_042468530.1|1749675_1750530_-|3-deoxy-8-phosphooctulonate-synthase
MEQKNIKINDIDVANDKPLVLFGGMNVLESRDMAMAVCEKYVEVTSKLGIPFVFKASWDKANRSSIHSYRGPGLEEGMKIFQELKATFGMPVISDLHEVHQAKPVAEVVDVIQLPAFLARQTDLVEAMARTGNVINIKKPQFLSPSQMKNITDKFEECGNDQLILCERGANFGYDNLVVDMLGLGVMKKSTGGYPVIFDVTHSLQCRDPLGAASGGRRDQVTELARAGMAVGLAGLFIESHPDPKVARCDGPSALPLDKLEGFLKQMKAIDDLIKGFEPLDTSA
>NZ_CP047374.1|WP_159364798.1|1748087_1749371_-|C4-dicarboxylate-transporter-DctA
MRNKIFSSLYFQVLLAITLGVFLGHVYPDLGADMKPLGDGFVKLIKMIIAPVIFCTVVTGIAGMESMKAVGKTGAIALLYFEVVSTIALVIGLCVVNLLQPGVGMNVDPATLDASAISAYAEQAKSQGIIAFLLDVIPGSVIGAFASGNILQVLLFAVLFGFSLHHIGEKGKLIFNVIDSFSQVIFGIINMIMRLAPVGAFGAMAFTIGKYGIGSLVQLGQLIACFYVTCLLFIFMVLGSIARANGFSILRFISYIKEELLIVLGTSSSESVLPRMLVKMEALGCKKSVVGLVIPTGYSFNLDGTSIYLTMAAIFIAQATNTPLDLFQQITLLVVLLISSKGAAGVTGSGFIVLAATISAVGHLSLAGLALILGIDRFMSEARALTNLIGNGVATVVVARYCDQLDEQQMNEVLANPAAVQKVDQHG
>NZ_CP047374.1|WP_005316999.1|1747601_1747982_+|autonomous-glycyl-radical-cofactor-GrcA
MIKGIQITQSANTALLNSFWLLDEEKQQARCICAKGDTFAADQEVKLSDLGQFEYRELPVQAEPAVEGGQHLNVNVLRRETLEDAIANPEKYPQLTIRVSGYAVRFNALTPEQQRDVVTRTFTQSL
>NZ_CP047374.1|WP_011899080.1|1746275_1747307_+|IS630-family-transposase
MPILPPLPRPQRRRIHKIIHATRDKGHARRLMAILLLHEGRTVTDVHHLTGAARSTIGRWLRWYRDEGIDALEALPAGRAPVLPIAKMVTLLVLLMQFSPQDFGYQRSRWCTELLAIKINRLTGLNVAASTLRRWLPRMGIVWRRPVPTLRIKDPAYQEKMANIDAALARCNADNPVFYEDEVDIDLNPKLGADWMFRAQQKRVVTPGQNAKHYLAGVLHAGNGRVLYVSGIKKNSSLFIAMLEKLRHHYRRAKTITLILDNYIIHKSKQTERWLKKNPKFCLVFQPVYSPWVNHIERLWHKLHETITRNHQCRGMANLLARVKYFMDTVSPFPGNGYGTAKV
>NZ_CP047374.1|WP_005316983.1|1745840_1746098_-|hypothetical-protein
MLWFIGSMGQGAMALEMGPVAIDLLFYIEGLYSPLGGSVTECGRWPAIPGAGDAPCCVLSLKDTALLGGLRRWRYGCVLLSGPLS
>NZ_CP047374.1|WP_159364797.1|1745140_1745809_-|uracil-DNA-glycosylase
MRTWTDVIGSEKEQDYFKATLATVRSEREAGKVIYPPATEVFNAFKLTELDQVKVVILGQDPYHGPNQAHGLCFSVLPGVRTPPSLVNIYKEMQRDLPDFVTPNHGFLESWAQQGVLLLNTVLTVQAGMAHSHAHLGWETFTDRVIEQINASCQGVVFLLWGVHAQKKGRFIDRSRHHVLSAPHPSPLSAHRGFIGCGHFSETNRLLSQQGMSPINWHSVCG
>NZ_CP047374.1|WP_005316978.1|1744345_1744894_-|hemerythrin
MLSSLHKDHLNIARLLTLLKHKLVAIRNEQPVSYFLIRDAVDYLREVSDKYHHPKEDMIYDYYLKYRVVEGEVANRLQEEHARLLGAGAELKEMVEMILMDSVIPLDQFTARLEQFVALQEAHMNYEEAVIFPHLRDSLTEDDWRHLEQLWQNRAIGDPLFGAEISQHFQELAQRLSLPPSS
>NZ_CP047374.1|WP_005316976.1|1744114_1744297_+|DUF3545-family-protein
MEMFNFDYDDVVELGSRSRGTTGKKRKWREIEALKDKHRLQKELQSIDIAYEGLSDEIEL
>NZ_CP047374.1|WP_159364796.1|1743004_1743955_+|transaldolase
MADKLTQLKALTTVVADTGDIEAIKRYQPIDATTNPSLVLKASEIPEYAALIEDAISWAKSQSQDKAQQIIDAGDKLAVNIGLEVLKIVPGRISTEVDARLSFDTEASIAKARKLIRLYNEAGIANDRILIKLASTWEGIRAAEVLEKEGIQCNLTLLFSFAQARACAEAGAFLISPFVGRILDWYKAKHNRDYTPSEDPGVVSVTAIYDYYKQHDYPTVVMGASFRNTGEILELAGCDRLTIGPALLEDLSKTEGAVVRKLNYTGERKAKPTPMSEAEFRWELNQDAMAHEKLGEGIRMFAVDQGKLETMLASRL
>NZ_CP047374.1|WP_088814343.1|1741436_1742573_+|ISAs1-family-transposase
MSIDAVFTQFFADIHDQRQNEKIHYAFYDVLFLTVCAVIGGAEGWEEIEDFGEIHLPWFQSKGLFKNGIPVHDTIARIISRIKPAQFQAAFIRWTNAINKQTDGALVAIDGKTLRRSYDREDRTSTIHMVSAYAAANKMVLGQLKTAAKSNEITAIPELLTLLDIKGCLISIDAMGCQTEIAKTIVEQQGDYLLAVKGNQPTLFDAVRKALAPQLTQPLNQERAAIEQQHGRIEAREYHVLEAGVLASQFPDWPGLQTIGVAVSYRTENKKKTTLDMRYFISSKLLERDEFAKAVRGHWAIENSLHWVLDVTMGEDACPIYRGDAAEILACIRHMALNMLRGETSRKASIRRKQKIAGMSSEYLEAVLTAGIQKLTAS
>NZ_CP047374.1|WP_159364799.1|1750781_1751582_-|tetratricopeptide-repeat-protein
MIRVDEWTDFEAHDIAELALSVSDEIHGISGRGEAELARLDAWLDEAIAEGSCDEVRRQLLQGFYQTLGFHGDWQDYFSAANSDLAQVLATKRGIPVSLGILIIQLGRKLGLDVEGICFPGHFLVSFAGSEGEVYVDPFTGDELSLHHMELLLRGALGNLATLTPEHLQPSGQWEIIERLLNVSKGALLREDRMTEALRCSELLLRMKPGDPLETRDRGFIYEQLDCPRFAADDFEYFIEQCPDDPVADVLKVQLAALDFSPKPLH
>NZ_CP047374.1|WP_005317005.1|1751593_1751977_-|SirB2-family-protein
MYFALKHLHLVLIASAVLMFMLRFYWVQTGSGRAYSDQIMKVSGWLNGLVVLSGVLLCMVLDLNPLNNGTPWLSEKLTAILVVAFLAMMALRLACNNGIRWFAFLGAIGWVFFIAKLAVYKQASLFG
>NZ_CP047374.1|WP_005317007.1|1752021_1752891_-|peptide-chain-release-factor-N(5)-glutamine-methyltransferase
MQIQQARAHIMATLAGGESPRADADVLLCHLLDCRRSYLMTWPERELDAAQQDRLQGWLTRRLAGEPIAHLVGEREFWSLPLKVSPATLIPRPDTEVLVEQALARLPPKPASPDQAPCALLDLGTGTGAIALALKSERPDADVWAVDRMPEAAALARDNSAALGLPITVRDGSWFEPLCDPLLSQAPRFAMIVSNPPYIDGADPHLNKGDVRFEPRSALVADEQGLADIRLIVAGAPAHLCPGGWLLLEHGWQQGEAVRQLLLQQGFSRVETVRDYGDNERVTLGCLAH
>NZ_CP047374.1|WP_005317010.1|1752940_1754029_-|peptide-chain-release-factor-1
MNPSLIRKLEGLIERHEEVQAMLGEPGVASDQDRYRALTREYAQLEDIVHAFQRFRQAEENLEATKLMLEEDDADLREMAQEELPLAKSTLEEQEQALQVMLLPRDPKDDNNCYLEIRAGAGGDEAAIFAGDLFRMYSRYAERQGWRISIVSCNDGEHGGYKEVIAKVDGEHVYGRLKFESGGHRVQRVPETESQGRVHTSACTVAVLPEVPEAEQIEINANDLKIDTFRASGAGGQHVNKTDSAIRITHLPTGLVVECQDERSQHKNRAKAMSVLSARLQAAEDERHRAAEQSTRRNLVGSGDRSERIRTYNYPQGRLSEHRINLTLYRLGEIMEGDLDCIISPMIQEYQADQLASLAENS
>NZ_CP047374.1|WP_042468526.1|1754082_1755339_-|glutamyl-tRNA-reductase
MSLLALGINHNTASVALRERVAFGPDCIDRALRELVTQPGVSEAVIVSTCNRTELYCSLEKGQGEQVLHWLQRFHGLDAAEVVSAIYQHQDEEAVRHLMRVACGLDSLVLGEPQILGQIKQSYAHAQQSEAVKGSLERLFQKSFSVAKRVRTDTEIGASAVSVAFAAVSLGRRIFSDLSQTKVLLVGAGETIELVARHLREQNVTCMMVANRTLQRAQLLAEEFGAQVMTLEEIPDYLHEADIVISSTASPLPIIGKGMVERALKARRFKPMFLVDIAVPRDIEAEVDELSDAYLYTVDDLQGIIEQNLETRKRAAAEAEIIVLEERDEFMGWYRSQHSVDLIRDYRHQAQQVADEELQRALLSLQQGENAEQALKAMAHRLTNKLIHAPTQALRQAAAQGDHHQLSRLRQVLGLPQE
>NZ_CP047374.1|WP_005317016.1|1755459_1756044_+|outer-membrane-lipoprotein-LolB
MTLFLRIFTFGCLLLLAGCTTTQPQRDQVNWQKERTRLEQLSHWQLSGKMAIITVQQKGSARVNWQQNGDDYRLNLTSLIGTHILELSRSNGEITLIDNEGNPHQSQDAEALIYQLTGWNIPVQGLPEWIKGLPGKAEFELNPDSSLASVRDGQWQIVYGDYRDQDGYRLPHLLTMTGQGSRLKLQINQWTLAR
>NZ_CP047374.1|WP_017412585.1|1756070_1756940_+|4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol-kinase
MATIRWPAPAKLNLFLNVNGRRPDGYHELQTLFIFLDHGDWLEFEPLPDTDQLTLSPAIPGVPDEQNLIIRAARLLQARLPSPQGAHIRLEKLLPMGGGIGGGSSDAATTLVALNHLWQAGLGEDELAELGVQLGADVPVFVRGRAAFAEGVGERLQPVELPGAWYLVLKPDCHVATAAVFQDPDLPRATPKMAFHNLLEGEWKNDCELLVKKRYPEVANALGWLLEYAPSRMTGTGACVFAQFEDEKAAREVLAKVPKRWDGFVAKGENISPLFVTLQQISDWGIAKR
>NZ_CP047374.1|WP_159364800.1|1757304_1758252_+|ribose-phosphate-diphosphokinase
MPDMKLFAGNATPELAQKIADRLFIKLGNAAVGRFSDGEISVQINENVRGGDIFIIQSTCAPTNDNLMELIVMVDALRRASAGRITVVIPYFGYARQDRRVRSARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPVLLEDMKSKNLESPVVVSPDIGGVVRARAIAKLLDDTDIAIIDKRRPRPNVSQVMHLIGDVAGRDCIIVDDMIDTGGTLCKAAEALKERGAKRVFAYATHPVFSGSAVENIKNSVIDELIITDSIPLTAEMKAVDKVKQLTLSTVLAEAIRRISNEESISAMFEH
>NZ_CP047374.1|WP_005317020.1|1758353_1760342_+|bifunctional-metallophosphatase/5'-nucleotidase
MNRLRPLLLLACCSFLFACQPGKENQPFALTLAHMNDTHSQFDPVNAELKGPIFGKQGETDTLYTRFGGYPRLLTMVKSYQAEALAKNQPLLLLHGGDAWQGSGYFKLNEGMANAELLSQFGLDAMALGNHEFDLDNQKLARFIEGVNFPLLAANLDTRDDPALRHATNLKPFVVYAFDGNQKSPVTDLNKLPQGKQLVAVMGLVLEDMANISPNVGKLRFGKEVESAQSTVDMLRKKGIHHVIALTHIGNERDLALASRVNGIDAIVGGHSHSLLGDFTNIGWGKTGEYAQLVTNPDGVGLTCVVQAGSYAQAIGLAWVSFDGQGRVIGCKGQNKLLASRDFFADPARQQALDKASGKQASKFVDAQPNLVTVDEDPRLRGIIDSHYKPALEQAFGPVIATVPAPLQNARRPGDNGSDSHGSDVAPLVAEGQYYWANTQAVQALTGGPVHFALLAVGGVRADLPAGELREGDTALTLLPFKNQLSVLTLSGADVRALLAETITATLPASAHAGKFPYGGHLRYTFTETEAGKRGDLTQLQWQTTEGQWQDLVDNQRYRVVMNAYSANGNDGWQALARAQSLRAERLDLAWVDGKLTGFPVEKVEQNGDQLNARYARGQTLDCQARVVNCGTDAASFVQYVREQRPTLTALSEPTVTLLRAE
>NZ_CP047374.1|WP_042468523.1|1760550_1761192_+|aminoacyl-tRNA-hydrolase
MTNQIKLIVGLGNPGPEYAKTRHNAGAWYVEQLARWHNVSLREEPKFFGHTARIQVEGQDVRLLIPNTYMNLSGKAVAALARFYQIEPEAMLVAHDELDLPPGIAKFKQGGGHGGHNGLKDIIARMGNNNNFFRLRLGIGHPGAKELVAGFVLTKAPSSEQNLIDAALDESLRATDILFKQDMTKAMNRLHSFKAGKYITGCACVPHSIYQVR

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Crispr_ID: NZ_CP047374_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047374_3

1870449-1870561

Orphan

Consensus_repeat	Method
AAAACAGGGGCACCAGGCCCCTGTTTCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP047374_3

>merge|NZ_CP047374|3|1870449-1870561|CRISPRCasFinder
AAAACAGGGGCACCAGGCCCCTGTTTCTGGGGGGTTAACATATCAAGCACATCAGACCCTGTATTTACAGGGGGATTAACCTAACAAAACAGGGGCACTAGGCCCCTGTTTCT

>NZ_CP047374|3|3|1870449-1870561|CRISPRCasFinder
AAAACAGGGGCACCAGGCCCCTGTTTCT	GGGGGGTTAACATATCAAGCACATCAGACCCTGTATTTACAGGGGGATTAACCTAAC
AAAACAGGGGCACTAGGCCCCTGTTTCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047374.1\|WP_085941500.1\|1867584_1868484_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176114
NZ_CP047374.1\|WP_005311610.1\|1873387_1873852_+\|thioredoxin-dependent-thiol-peroxidase	unknown	unknown	gnl\|CDD\|181857
NZ_CP047374.1\|WP_005311619.1\|1868581_1869184_+\|short-chain-dehydrogenase	unknown	unknown	gnl\|CDD\|236057
NZ_CP047374.1\|WP_011899053.1\|1874856_1875297_-\|DUF412-domain-containing-protein	unknown	unknown	gnl\|CDD\|377248
NZ_CP047374.1\|WP_017412149.1\|1874295_1874796_+\|YfbU-family-protein	unknown	unknown	gnl\|CDD\|180087
NZ_CP047374.1\|WP_005311605.1\|1879431_1879926_-\|acetolactate-synthase-small-subunit	unknown	unknown	gnl\|CDD\|183365
NZ_CP047374.1\|WP_042467240.1\|1876872_1879026_+\|phosphate-acetyltransferase	unknown	unknown	gnl\|CDD\|235537
NZ_CP047374.1\|WP_005311623.1\|1866880_1867513_-\|DUF2057-domain-containing-protein	unknown	unknown	gnl\|CDD\|378258
NZ_CP047374.1\|WP_005311626.1\|1865574_1866273_-\|DUF3334-family-protein	unknown	unknown	gnl\|CDD\|314646
NZ_CP047374.1\|WP_005311630.1\|1861986_1864299_-\|aerobic-respiration-two-component-sensor-histidine-kinase-ArcB	unknown	unknown	gnl\|CDD\|236842
NZ_CP047374.1\|WP_005311611.1\|1872831_1873365_+\|glycine-cleavage-system-transcriptional-repressor	unknown	unknown	gnl\|CDD\|236935
NZ_CP047374.1\|WP_159364810.1\|1879925_1881644_-\|acetolactate-synthase-3-large-subunit	unknown	unknown	gnl\|CDD\|181602
NZ_CP047374.1\|WP_005311632.1\|1860566_1861931_-\|dGTPase	unknown	unknown	gnl\|CDD\|235320
NZ_CP047374.1\|WP_005311635.1\|1860040_1860244_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047374.1\|WP_159364809.1\|1871676_1872564_-\|4-hydroxy-tetrahydrodipicolinate-synthase	unknown	unknown	gnl\|CDD\|235107
NZ_CP047374.1\|WP_085941645.1\|1869312_1870428_-\|phosphoribosylaminoimidazolesuccinocarboxamide-synthase	unknown	unknown	gnl\|CDD\|184420
NZ_CP047374.1\|WP_005311601.1\|1882034_1882187_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047374.1\|WP_034283655.1\|1864506_1865505_+\|DUF2860-domain-containing-protein	unknown	unknown	gnl\|CDD\|371359
NZ_CP047374.1\|WP_005311624.1\|1866371_1866809_-\|HIT-domain-containing-protein	unknown	unknown	gnl\|CDD\|334445
NZ_CP047374.1\|WP_005311607.1\|1875599_1876802_+\|acetate-kinase	unknown	unknown	gnl\|CDD\|234680

Protein	Function_ID	Function_description	E-value
NZ_CP047374.1\|WP_085941500.1\|1867584_1868484_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.24107e-55
NZ_CP047374.1\|WP_005311610.1\|1873387_1873852_+\|thioredoxin-dependent-thiol-peroxidase	gnl\|CDD\|181857	PRK09437, bcp, thioredoxin-dependent thiol peroxidase; Reviewed.	6.82136e-106
NZ_CP047374.1\|WP_005311619.1\|1868581_1869184_+\|short-chain-dehydrogenase	gnl\|CDD\|236057	PRK07578, PRK07578, short chain dehydrogenase; Provisional.	9.39282e-124
NZ_CP047374.1\|WP_011899053.1\|1874856_1875297_-\|DUF412-domain-containing-protein	gnl\|CDD\|377248	pfam04217, DUF412, Protein of unknown function, DUF412. This family consists of bacterial proteins, including yfbV from E. coli. YfbV is a membrane protien involved in insulating the chromosome from the TerR macrodomain.	2.85575e-63
NZ_CP047374.1\|WP_017412149.1\|1874295_1874796_+\|YfbU-family-protein	gnl\|CDD\|180087	PRK05445, PRK05445, YfbU family protein.	3.22814e-85
NZ_CP047374.1\|WP_005311605.1\|1879431_1879926_-\|acetolactate-synthase-small-subunit	gnl\|CDD\|183365	PRK11895, ilvH, acetolactate synthase 3 regulatory subunit; Reviewed.	6.20447e-96
NZ_CP047374.1\|WP_005311623.1\|1866880_1867513_-\|DUF2057-domain-containing-protein	gnl\|CDD\|378258	pfam09829, DUF2057, Uncharacterized protein conserved in bacteria (DUF2057). This domain, found in various prokaryotic proteins, has no known function.	1.10247e-39
NZ_CP047374.1\|WP_005311626.1\|1865574_1866273_-\|DUF3334-family-protein	gnl\|CDD\|314646	pfam11813, DUF3334, Protein of unknown function (DUF3334). This family of proteins are functionally uncharacterized. This family is only found in bacteria. Proteins in this family are typically between 227 to 238 amino acids in length.	1.73798e-148
NZ_CP047374.1\|WP_005311630.1\|1861986_1864299_-\|aerobic-respiration-two-component-sensor-histidine-kinase-ArcB	gnl\|CDD\|236842	PRK11091, PRK11091, aerobic respiration control sensor protein ArcB; Provisional.	0
NZ_CP047374.1\|WP_005311611.1\|1872831_1873365_+\|glycine-cleavage-system-transcriptional-repressor	gnl\|CDD\|236935	PRK11589, gcvR, glycine cleavage system transcriptional repressor; Provisional.	8.05624e-47
NZ_CP047374.1\|WP_159364810.1\|1879925_1881644_-\|acetolactate-synthase-3-large-subunit	gnl\|CDD\|181602	PRK08979, PRK08979, acetolactate synthase 3 large subunit.	0
NZ_CP047374.1\|WP_005311632.1\|1860566_1861931_-\|dGTPase	gnl\|CDD\|235320	PRK04926, dgt, deoxyguanosinetriphosphate triphosphohydrolase; Provisional.	0
NZ_CP047374.1\|WP_042467240.1\|1876872_1879026_+\|phosphate-acetyltransferase	gnl\|CDD\|235537	PRK05632, PRK05632, phosphate acetyltransferase; Reviewed.	0
NZ_CP047374.1\|WP_159364809.1\|1871676_1872564_-\|4-hydroxy-tetrahydrodipicolinate-synthase	gnl\|CDD\|235107	PRK03170, PRK03170, dihydrodipicolinate synthase; Provisional.	1.38222e-163
NZ_CP047374.1\|WP_085941645.1\|1869312_1870428_-\|phosphoribosylaminoimidazolesuccinocarboxamide-synthase	gnl\|CDD\|184420	PRK13960, PRK13960, phosphoribosylaminoimidazole-succinocarboxamide synthase; Provisional.	0
NZ_CP047374.1\|WP_034283655.1\|1864506_1865505_+\|DUF2860-domain-containing-protein	gnl\|CDD\|371359	pfam11059, DUF2860, Protein of unknown function (DUF2860). This bacterial family of proteins has no known function.	2.97984e-69
NZ_CP047374.1\|WP_005311624.1\|1866371_1866809_-\|HIT-domain-containing-protein	gnl\|CDD\|334445	pfam01230, HIT, HIT domain.	1.78311e-19
NZ_CP047374.1\|WP_005311607.1\|1875599_1876802_+\|acetate-kinase	gnl\|CDD\|234680	PRK00180, PRK00180, acetate kinase A/propionate kinase 2; Reviewed.	0

>NZ_CP047374.1|WP_085941645.1|1869312_1870428_-|phosphoribosylaminoimidazolesuccinocarboxamide-synthase
MLLAMSLADQVLAVNDDLPIRTDKPVHSGKVRSVYWLTPEDSARLIKEKGYDVPADAPLALMVISDRISAFDCIWQGVDGLNGVPGKGAALNAISSHWFKLFKEKGLADSHILDIPHPFVWIVQKARPVMIEAIARQYITGSMWRAYKDGEREFCGITLPEGLKKDQKLPEILITPSTKGVLTGLDGVPEADDVNVSRADIERHYQGFNFSKPADIDRYEVLLKEGFNVISDALASLDQIFVDTKFEFGYVQDAAGNEKLIYMDEVGTPDSSRIWDGAALRDGQIVEKSKEGFRQWLLNHFPDPDILLNKNRMPERFALAKGNKLPTEVMMDISNTYVGIAEKIIGHPLVRSANPKQEIIEVLRDQYGLID
>NZ_CP047374.1|WP_005311619.1|1868581_1869184_+|short-chain-dehydrogenase
MKIVIVGASGTVGSAVSELLAKDHQVIRVGHSRGDATVDMRDPASIKALFALVGQFDALVVASGSVAFNGLTEMTDEQWQVGLQSKLMGQINLTRAAIPYLNDKGSITLISGILSEEPINWGVSATTINGAIEHFVKAAACELPKGLRINVVSPTVLTESMDKYADFFPGFVPVPAAKVALAYQKSVLGVQTGQVFKVNG
>NZ_CP047374.1|WP_085941500.1|1867584_1868484_-|LysR-family-transcriptional-regulator
MDIAHLASFYEVVQRGSFSAAADVLGVSKGMLSRHVSALEAALNAQLLQRTTRRLSLTEAGKTLYLQTGQIFALVRQAEEDIQALTEEDAGRLRFTCAVSTGDRMVSELLGHFAVLCPGVEVELNFTNAMVDMSQGENDIALRAMSSIPDNLVALPLGQLKDVVVASPALLVREGIPATPYELSSRPCLLQGSNPAWEQWHFRRGEEEAHILVQGKVRANHYSTVLQLARAGMGYAKCPLMLVEPALAAGELVTVLDGWQSGLHQLHVLHAQQRRVPRKIRLFKQVLAQWFAERPRYLL
>NZ_CP047374.1|WP_005311623.1|1866880_1867513_-|DUF2057-domain-containing-protein
MKGYQKWSGLTLLWSALGMSTAQAAVEVVVPPDFQILAVSAGKLQDEQHATLADGEQQLLVRYEGVIPSRNSSENDRQVRSDPQVVRYQASNQRLTLVAQQPADEQAMVAYAKAPVVTLQANGQALDTQQDALMTSGMLIGMDWRARLEEYNRSGGKAALTMAGVATTVAAGKAVPAVATSELEGRLQQLFLQADPELRKRFVGWAVPRL
>NZ_CP047374.1|WP_005311624.1|1866371_1866809_-|HIT-domain-containing-protein
MFELHTRLQADTQLLGDLPLCRVLLAKDSQYPWLILVPRVDNLREIHHLAPAQQQQLMQESCAVATLMEQALSPDKINIGALGNLVPQLHLHHVARFTTDKAWPGPIWGAHPALPYDPQALRTQADSWRARLAHLAGFIPLCVDN
>NZ_CP047374.1|WP_005311626.1|1865574_1866273_-|DUF3334-family-protein
MIVTRADNDAVLTTEDVLLSLCHSVTGVLSAATQSQVRFSGMVQRISKTCLKPDIGCFVLFDGGFSGLVVINFSASAAMELYESYMLSMGLSKEDLAISHTSDEVSNVMGELMNQIVGSFTVKVGRDLQTHITQNQPKMLALNKQVMLSVDTNLDNPEARRVTFFTSRNNIFYLELAMDRTEFIRIHSDGMDEEELDPDALIAQTKLAASKPTPVAAKVANEHDDLLDSLGI
>NZ_CP047374.1|WP_034283655.1|1864506_1865505_+|DUF2860-domain-containing-protein
MRTLTLLSLGLLAANAAHADLGEIPKQSGWSGFLLGGVNAVSYKSNFYAGDDSNSRINDLGSPDSESGLTPLINADIRYTFADTRTQVFLGNLIQDAIRFDFTQQLGLRQEMGDKGIVATSLVFNAMPVELWSDPFATNVDRSSTDVKSKGVRFTWDKIWGSNFHGSLTSREVDLDEERSGQQYDLTHGTHYASMLDRNGKVHDMEISYQWHFGGNQLLEPAILYKQARLDGSAESFKNTGLQLTYAKRGPQWSIVSNVYAGKRNYDEANPIFGQSADANEFAINGTFFWHSLFGVKDLAATFTAAYSTANSDISFYDSQATRVSTGLLYNF
>NZ_CP047374.1|WP_005311630.1|1861986_1864299_-|aerobic-respiration-two-component-sensor-histidine-kinase-ArcB
MKQIKSWAQYYVDLMTKLGLVRFSMFLATGIIVLAVSIQMGVTLFLRGTVDIVDLVRSVFFGLLVTPWAVYFLSIVVDQLEDSRQRLTRMVRKLQDMRERDLELNSQLQENISRLNAQIAETNRAETLRQQAIEDLENEVFQREKAQLHLGERTALLRSFIDCSPDLVYYRNEDEQFSGCNRAMEELTGRVEAELIGLTPFDVYKQEIANKVVETDKQVFTSNEPLTYEQWLEYPDGRKAYFELRKVPFFDRFGKRLGLLGFGRDITERKQYQDKLEKASRDKTTFISTISHELRTPLNGIVGLSRMLMDTPLDPRQHQQLKTIHLSAVTLGNIFNDIIDLDKLDRRRLEIAPTPIDLPAFLDELETLSRIQAEQKGLYLHFDRDGDMPQFVMADGTRLRQVLWNLVGNAVKFTDEGGVTVRCLSHAADVPGKLALHFEVEDTGVGIPRAQQEKIFAMYYQVQGKKHATGTGIGLAVSRQLVQAMGGQLYVDSDPGEGSCFTAELEVDCVEPQVATSEQEMPTLDILLVEDVELNVTVACALLNKLGHEVKVARDGAQALAMANPDDFDLILLDIQLPDMTGFDVAAQLLARYGDSLPPMVALTANATGDRQYYRDRGLQDVISKPLGSRAVREVIGHLFADLADDEADEQADAGNQDALLDLAFLTDYADTVGKPVLLSSVELFEKMMPDYMAVLDSNMIAKDQAGVVEEAHKIKGAAGSIGLRRLQQLAQLIQSPDHPAWWENVEDWIESLRRECPGDIARLKRWLLS
>NZ_CP047374.1|WP_005311632.1|1860566_1861931_-|dGTPase
MYQRLIPSLRSHPWGEEELLEATELDRARIVQAAPVRRLQQKTQVFPLDVKASVRSRLTHSLEVQETGRQISRRILAALPAGAVCEGAFINLVEMSCLLHDVGNPPFGHFGEQVMSQWLTQELDTLFAAALGQAPSPQWAELRQDLLVFDGNAQSLRLVHSLHELNLTLGQLAALCKYPQQPQPGLHYGQHHGWTSKRGIFFSEQPLYRSLSQSLGLAPGCRHPLVYIMEAADDISYCIADLEDAVDRRILSLSELQQALRLADAGSYMAVLLADATASDRGFFPHFRQHLTHDLIALAAHTYVSEHEIILSGAYPQALLHGQAPAAMVLDTLKQVAREQVFMRPEVEALELEGYAALRGVLSTYACLLALPASQFERLLAGQGGSELFFARRLFHRLSARHLKAYRLAVASRDPRFDSGAEQEWYYRVRLLLDYVSGMTDTYALEEFRLLSGI
>NZ_CP047374.1|WP_005311635.1|1860040_1860244_-|hypothetical-protein
MSIELALLRTVESLVQKRITRLERRISYLHLSPALLKDIGLEGQNVQIAHIREQEYQTGFRLGNRIT
>NZ_CP047374.1|WP_159364809.1|1871676_1872564_-|4-hydroxy-tetrahydrodipicolinate-synthase
MLRGSLVALVTPMLASGEVDWASLATLVDYHVSAGTAAIVAVGTTGESVTLSKQEHIAVVEKTVELAAGRIPVIAGCGSNNTAHAIALAKRFAETGVVAGLSVTPYYNKPTQEGLYRHYCTIAEASGLPQILYNVPSRTCCDLKPETVARLARVPGIIGLKEATGDLSRTPLLRELCGEEFALYSGDDASGCDFMLQGGDGVISVTTNIAAAQMADMCRAALAGDAGQAHDINNRLMPLHQTLFCEPSPIPVKWACARLGLIATATLRLPLTDLTPEGEQAMTRALTTAELMASV
>NZ_CP047374.1|WP_005311611.1|1872831_1873365_+|glycine-cleavage-system-transcriptional-repressor
MTHYLVVTAIGTDRPGIVNEVTRHVSGCGCNIVDSRLGIFGNEFTFIMLLSGDWNSLMQLEISLPLRSQEWELITMMKRTERHHSLQYDISANAEILIRDQPGIVSQCTQFFSDHGWDIQAMQTMTLEQQPYNLLKASFQLNLAKQGEAAGSDTAFAGFCRELGAESFEFIVNNKHA
>NZ_CP047374.1|WP_005311610.1|1873387_1873852_+|thioredoxin-dependent-thiol-peroxidase
MQPLSAGTLAPDFSLSDQDGNPVRLSDLRGKKVLIYFYPKAMTPGCTTQACGLRDVNSELAALNVVVLGISPDPAKHLKKFEERDSLNFRLLADEDHAVADAFGVWGPKKFMGKEYDGIHRLSFLIDEEGKIAHRFDKFKTSDHHQVVLDLIKG
>NZ_CP047374.1|WP_017412149.1|1874295_1874796_+|YfbU-family-protein
MNMSHTERLILSNQYEILAKLNPEKAASYQRASTIIARGYCLQILELEKSFGHLDLATCQEVIDTLELHHALAISWGNLDGADQSEITASRLEFNGYSRSQERELADYVCFLLEVDKRFPELKCPCDELSSDIAMRDKYQRMLTVWRQCPRQYKLSIQEIRKVLAA
>NZ_CP047374.1|WP_011899053.1|1874856_1875297_-|DUF412-domain-containing-protein
MSMNIFGTKLQQGRHYMTLWPRRPELNSMFPENRVIKATEFALKIIPALAVLSVMLQFQLGELHYWPSVMTSVLFLLSLPLQGYYWLGQRADTRLPPSLASWYREINGKMNEQGSHRQLVAQPRYEELADTLNAAFKQLDKSFLYE
>NZ_CP047374.1|WP_005311607.1|1875599_1876802_+|acetate-kinase
MSKLVLVLNCGSSSLKFAVIDATTGDDLLSGLAECFNLDDARIKWKLNGEKGSADLGAGAAHQEALDYIVNKILPLNPELSQNLIAIGHRVVHGGERFTSSVVICDDVIAGIEAAVPYAPLHNPAHLIGIREARRIFPALADKNVAVFDTAFHQTMPEEAFLYALPYKLYKENGIRRYGAHGTSHYYISLEAAKQLNKPVDELNIINCHLGNGGSVCAIKNGKSVDTSMGLTPLEGLVMGTRSGDLDPAIIFFLHDKLGMSVADINTMLTKESGLQGLTEVTSDCRFVEDNYDSKEEAKRAMDVYCYRLAKYIGAYAAAMDGRLDAVVFTGGIGENSAPIREITLNKLGLLGFDVDHDANLAARFGKGGEITKAGSTKALVIPTNEEWVIAHDALELVGA
>NZ_CP047374.1|WP_042467240.1|1876872_1879026_+|phosphate-acetyltransferase
MARTIMLIPVGTGVGVTSVSLGVVRAMERHGVNVSFFKPVAQPRPGETGTERSTAVIRAAANINPPEPFALSYAENMITSSNTDILLEEIVARFEEHVKASGAEVLVIEGMVPTDKQPFANKLNYDVAKALDADMVFVTHPGNDSSQKLKERIELACSNFGGVNNPRIVGCVINKVGAPVDEHGVTRPDLTEMFEAHHHASEAAHNLEVLQVFGKSPLRILGCIPWNTQLIAPRAKDLAKHLAAKILHKGELDSRRLQTVTFCARSIHNMVEHFRPGSLLVTSGDRSDVIVSACLSAMNGVKLGALLLTGNYHPEPQVMALCQQAMATGLPIMITGTNTWQTAVSLQNFNVDIPEDDRERIELVQDYVAGHIDKHWIESLSAKSTRSRRLSPPAFRYQLTELARQANKRVVLPEGEEPRTIKAASICAERGIARPVLLGNPEEIRRVAEQQGVVLTDRVEIIDPLEVRERYVPRLVELRKNKGMTEVVAREQLEDNVVLGTMMLERGEVDGLVSGAVHTTANTIRPPMQIIKTAPGSSLISSIFFMLLPDQVLVYGDCAINPDPTAEQLAEIAIQSADSAAAFGIEPRVAMISYSTGTSGAGADVEKVREATELAKAKRPDLIIDGPLQYDAAIMENVAKSKAPNSPVAGKATVFVFPDLNTGNTTYKAVQRSADLVSIGPMLQGMRKPVNDLSRGALVDDIVYTIALTGIQAAQAE
>NZ_CP047374.1|WP_005311605.1|1879431_1879926_-|acetolactate-synthase-small-subunit
MRHIISVLLENESGALSRVVGLFSQRGYNIETLTVAPTEDPTLSRMTIVTMGDERVLEQIQKQLHKLVDVLKVCDLSEGEHIEREIALVKARAAGGARDELKRLADIFRGQIVDVTPEQYTVQLVGTSEKLDAFIKTAAQTNEIIEVVRSGVCGISRADKALRP
>NZ_CP047374.1|WP_159364810.1|1879925_1881644_-|acetolactate-synthase-3-large-subunit
MEMLSGAQMVVRALEDQGVEHVFGYPGGSVLDIYDALFENGKMEHVLVRHEQAAVHMADGYARSTGKVGTVLVTSGPGATNCITGIATAYMDSIPLVILSGQVPTSMIGEDAFQETDMIGISRPVVKHSFLCKKASDIPDAIKKAYYIAASGRPGPVVVDLPKDVQNPKEKFPYQYPETVSLRSYNPTKAGHKGQIKRAAKLLVDAQRPVMYVGGGAINANADHLVTKLAELLNLPVTTTLMGLGAFSGTHPQFVGMLGMHGTFEANKTMHNADLIFAVGARFDDRVTNNVAKFCPNATIVHIDIDPTSISKTVQAHVPIVGSVETVLEQMLEVIRECGFDNDKQALADWWSQIAQWRSRNCLAYETHPTLIKPQQVIETLYKVTKGEAFVASDVGQHQMFVALYYPFAKPRQWINSGGLGTMGFGIPAAMGAQFANPGAVVCCVTGDGSVQMNIQELSTCMQYGVPIKIISINNRALGMVKQWQKMFYGGRHSHSYMESLPDFVKLAEAYGHVGIAVSDPAELESVMEKAFAIKDRLVFMDISVDPDEHVYPMQIKFGAMDEMWLSKTERT
>NZ_CP047374.1|WP_005311601.1|1882034_1882187_-|hypothetical-protein
MRFTNENGDTMTLADNLTLHELLDMGVSISVCEETDPDQQIWLAESEDEQ

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Crispr_ID: NZ_CP047374_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047374_4

2094313-2094412

Unclear

Consensus_repeat	Method
CCTCGCCTTTATCGGCGCAGGCA	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of NZ_CP047374_4

>merge|NZ_CP047374|4|2094313-2094412|CRISPRCasFinder
CCTCGCCTTTATCGGCGCAGGCAGCGCAGGTGTTTGCAGCCATTTCATCCACAGGAGTGTTTGATGCAGCAGAGAATCCTCGCCTTTATCGGCGCAGGCA

>NZ_CP047374|4|4|2094313-2094412|CRISPRCasFinder
CCTCGCCTTTATCGGCGCAGGCA	GCGCAGGTGTTTGCAGCCATTTCATCCACAGGAGTGTTTGATGCAGCAGAGAAT
CCTCGCCTTTATCGGCGCAGGCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047374.1\|WP_011899099.1\|2096585_2096885_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047374.1\|WP_005320497.1\|2101774_2102215_+\|copper-chaperone-PCu(A)C	unknown	unknown	gnl\|CDD\|377298
NZ_CP047374.1\|WP_005320479.1\|2095779_2096079_+\|YggU-family-protein	unknown	unknown	gnl\|CDD\|179931
NZ_CP047374.1\|WP_005320452.1\|2086037_2086499_+\|chemotaxis-protein-CheX	unknown	unknown	gnl\|CDD\|381734
NZ_CP047374.1\|WP_085941509.1\|2086470_2086734_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047374.1\|WP_085941508.1\|2100935_2101715_-\|enoyl-CoA-hydratase	unknown	unknown	gnl\|CDD\|235852
NZ_CP047374.1\|WP_159364837.1\|2095228_2095780_+\|YggT-family-protein	unknown	unknown	gnl\|CDD\|376765
NZ_CP047374.1\|WP_005320482.1\|2096097_2096517_+\|DUF4426-domain-containing-protein	unknown	unknown	gnl\|CDD\|379616
NZ_CP047374.1\|WP_005320494.1\|2100503_2100932_+\|DUF2753-family-protein	unknown	unknown	gnl\|CDD\|287867
NZ_CP047374.1\|WP_005320466.1\|2092509_2093544_-\|type-IV-pilus-twitching-motility-protein-PilT	unknown	unknown	gnl\|CDD\|225364
NZ_CP047374.1\|WP_017412061.1\|2088308_2089019_-\|methyltransferase	unknown	unknown	gnl\|CDD\|226608
NZ_CP047374.1\|WP_005320451.1\|2085589_2086048_+\|zinc-uptake-transcriptional-repressor-Zur	unknown	unknown	gnl\|CDD\|183251
NZ_CP047374.1\|WP_005320464.1\|2090559_2091333_-\|peroxide-stress-protein-YaaA	unknown	unknown	gnl\|CDD\|234999
NZ_CP047374.1\|WP_159364838.1\|2096994_2098599_-\|oligopeptide-ABC-transporter-substrate-binding-protein-OppA	unknown	unknown	gnl\|CDD\|185059
NZ_CP047374.1\|WP_005320489.1\|2098780_2099488_+\|chromosome-partitioning-protein-ParB	unknown	unknown	gnl\|CDD\|378068
NZ_CP047374.1\|WP_005320465.1\|2091364_2092474_-\|PilT/PilU-family-type-4a-pilus-ATPase	unknown	unknown	gnl\|CDD\|227341
NZ_CP047374.1\|WP_005320467.1\|2093583_2094285_+\|YggS-family-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|143497
NZ_CP047374.1\|WP_159364836.1\|2086809_2088117_-\|branched-chain-amino-acid-transport-system-II-carrier-protein	unknown	unknown	gnl\|CDD\|283235
NZ_CP047374.1\|WP_005320492.1\|2099535_2100198_-\|CatB-related-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100040
NZ_CP047374.1\|WP_005320462.1\|2089147_2090371_+\|ATP-dependent-RNA-helicase-SrmB	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|236877

Protein	Function_ID	Function_description	E-value
NZ_CP047374.1\|WP_005320497.1\|2101774_2102215_+\|copper-chaperone-PCu(A)C	gnl\|CDD\|377298	pfam04314, PCuAC, Copper chaperone PCu(A)C. PCu(A)C is a periplasmic copper chaperone. Its role may be to capture and transfer copper to two other copper chaperones, PrrC and Cox11, which in turn deliver Cu(I) to cytochrome c oxidase.	6.17212e-42
NZ_CP047374.1\|WP_005320479.1\|2095779_2096079_+\|YggU-family-protein	gnl\|CDD\|179931	PRK05090, PRK05090, hypothetical protein; Validated.	7.2285e-55
NZ_CP047374.1\|WP_005320489.1\|2098780_2099488_+\|chromosome-partitioning-protein-ParB	gnl\|CDD\|378068	pfam08857, ParBc_2, Putative ParB-like nuclease. This domain is probably distantly related to pfam02195. Suggesting these uncharacterized proteins have a nuclease function.	1.22063e-70
NZ_CP047374.1\|WP_085941508.1\|2100935_2101715_-\|enoyl-CoA-hydratase	gnl\|CDD\|235852	PRK06688, PRK06688, enoyl-CoA hydratase; Provisional.	7.64876e-86
NZ_CP047374.1\|WP_159364837.1\|2095228_2095780_+\|YggT-family-protein	gnl\|CDD\|376765	pfam02325, YGGT, YGGT family. This family consists of a repeat found in conserved hypothetical integral membrane proteins. The function of this region and the proteins which possess it is unknown.	1.49976e-12
NZ_CP047374.1\|WP_005320482.1\|2096097_2096517_+\|DUF4426-domain-containing-protein	gnl\|CDD\|379616	pfam14467, DUF4426, Domain of unknown function (DUF4426). Members of this entry are found mostly in g-proteobacteria, especially in Vibrio. Strangely enough, there seems to be one eukaryotic homolog in Nematostella vectensis (NEMVEDRAFT_v1g226006), where the PA0388-like domain is fused with a domain homogous to the Methionine biosynthesis protein MetW (see below). In several Pseudomonas species, but also in Vibrio vulnificus and Azotobacter vinelandii PA0388 homologs are genomic neighbors of Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) and Methionine biosynthesis protein MetW. On the other hand, in most Vibrio species it appears as a part of a conserved operon involved in possible response to stress.	4.01045e-58
NZ_CP047374.1\|WP_005320494.1\|2100503_2100932_+\|DUF2753-family-protein	gnl\|CDD\|287867	pfam10952, DUF2753, Protein of unknown function (DUF2753). This bacterial family of proteins has no known function.	8.70931e-75
NZ_CP047374.1\|WP_005320466.1\|2092509_2093544_-\|type-IV-pilus-twitching-motility-protein-PilT	gnl\|CDD\|225364	COG2805, PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion].	0
NZ_CP047374.1\|WP_017412061.1\|2088308_2089019_-\|methyltransferase	gnl\|CDD\|226608	COG4123, COG4123, Predicted O-methyltransferase [General function prediction only].	5.11955e-75
NZ_CP047374.1\|WP_005320451.1\|2085589_2086048_+\|zinc-uptake-transcriptional-repressor-Zur	gnl\|CDD\|183251	PRK11639, PRK11639, zinc uptake transcriptional repressor Zur.	2.04149e-52
NZ_CP047374.1\|WP_005320464.1\|2090559_2091333_-\|peroxide-stress-protein-YaaA	gnl\|CDD\|234999	PRK02101, PRK02101, peroxide stress protein YaaA.	1.02245e-150
NZ_CP047374.1\|WP_159364838.1\|2096994_2098599_-\|oligopeptide-ABC-transporter-substrate-binding-protein-OppA	gnl\|CDD\|185059	PRK15104, PRK15104, oligopeptide ABC transporter substrate-binding protein OppA; Provisional.	0
NZ_CP047374.1\|WP_005320452.1\|2086037_2086499_+\|chemotaxis-protein-CheX	gnl\|CDD\|381734	cd17906, CheX, chemotaxis phosphatase CheX. This family contains CheX CheY-P phosphatase which is very closely related to CheC chemotaxis phosphatase; both dephosphorylate CheY, although CheC requires binding of CheD to achieve the level of activity of CheX. CheX has been shown to be the most powerful CheY-P phosphatase of the CheC-FliY-CheX (CXY) family. Structural and functional data of CheX and its CheY3 substrate in Borrelia burgdorferi (the causative agent of Lyme disease) bound to the phosphoryl analog BeF3(-) and Mg2+ reveal a unique mode of binding, but a catalytic mechanism which is virtually identical to that used by the structurally unrelated CheZ, providing a striking example of convergent evolution. Thus, CheX is quite divergent from the rest of the CXY family; it forms a dimer and some may function outside chemotaxis. The data also suggest a possible CheX regulatory mechanism through dissociation of the CheX homodimer.	2.53743e-52
NZ_CP047374.1\|WP_005320465.1\|2091364_2092474_-\|PilT/PilU-family-type-4a-pilus-ATPase	gnl\|CDD\|227341	COG5008, PilU, Tfp pilus assembly protein, ATPase PilU [Cell motility and secretion / Intracellular trafficking and secretion].	0
NZ_CP047374.1\|WP_005320467.1\|2093583_2094285_+\|YggS-family-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|143497	cd06824, PLPDE_III_Yggs_like, Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins. This subfamily contains mainly uncharacterized proteobacterial proteins with similarity to the hypothetical Escherichia coli protein YggS, a homolog of yeast YBL036c, which is homologous to a Pseudomonas aeruginosa gene that is co-transcribed with a known proline biosynthetic gene. Like yeast YBL036c, Yggs is a single domain monomeric protein with a typical TIM-barrel fold. Its structure, which shows a covalently-bound PLP cofactor, is similar to the N-terminal domain of the fold type III PLP-dependent enzymes, bacterial alanine racemase and eukaryotic ornithine decarboxylase, which are two-domain dimeric proteins. YggS has not been characterized extensively and its biological function is still unkonwn.	4.9929e-133
NZ_CP047374.1\|WP_159364836.1\|2086809_2088117_-\|branched-chain-amino-acid-transport-system-II-carrier-protein	gnl\|CDD\|283235	pfam05525, Branch_AA_trans, Branched-chain amino acid transport protein. This family consists of several bacterial branched-chain amino acid transport proteins which are responsible for the transport of leucine, isoleucine and valine via proton motive force.	7.77557e-144
NZ_CP047374.1\|WP_005320492.1\|2099535_2100198_-\|CatB-related-O-acetyltransferase	gnl\|CDD\|100040	cd03349, LbH_XAT, Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. Members of this class of enzymes include Enterococcus faecium streptogramin A acetyltransferase and Pseudomonas aeruginosa chloramphenicol acetyltransferase. They contain repeated copies of a six-residue hexapeptide repeat sequence motif (X-[STAV]-X-[LIV]-[GAED]-X) and adopt a left-handed parallel beta helix (LbH) structure. The active enzyme is a trimer with CoA and substrate binding sites at the interface of two separate LbH subunits. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients.	3.73127e-64
NZ_CP047374.1\|WP_005320462.1\|2089147_2090371_+\|ATP-dependent-RNA-helicase-SrmB	gnl\|CDD\|236877	PRK11192, PRK11192, ATP-dependent RNA helicase SrmB; Provisional.	0

>NZ_CP047374.1|WP_005320467.1|2093583_2094285_+|YggS-family-pyridoxal-phosphate-dependent-enzyme
MSQIAQHLLQVKERIVQAARQADRCVDHINLLAVSKTKPLEAIREAYAAGQRRLGESYAQEAATKIDTLRKQAVCTDIEWHFIGPLQSNKSRLVAERFDWVQSVDRDKLIERLNNQRPAGLAPLNICLQINISGESSKSGTSEQEIFRLAELVSRSERLVLRGLMAIPEHTSDEAVLAAQMVRMQTLFTELAQQYPSVDTLSMGMTEDLELAIAHGSTMVRVGTAIFGARDYS
>NZ_CP047374.1|WP_005320466.1|2092509_2093544_-|type-IV-pilus-twitching-motility-protein-PilT
MDITELLAFSVKHKASDLHLSAGVPPMIRVDGEVRKINLPALEHREVHALIYDIMNDHQRKELEENFEVDFSFEVPNLARFRVNAFQQSRGSGAVFRTIPSTVLSLEDLDAPEIFRKISEYPRGLVLVTGPTGSGKSTTLAAMVNYINENFHHHILTIEDPIEFVHENKRCLVNQREVHRDTKSFSNALRSALREDPDIILVGEMRDLETIRLAMTAAETGHLVFGTLHTSSAAKTIDRIIDVFPGAEKDMVRSMLSESLRAVISQTLLKRIGGGRVAAHEIMMGIPAVRNLIREDKIAQLYSVIQTGMTHGMQTMDQSLKQLVSRGVVASLDAKAKAVDPNSV
>NZ_CP047374.1|WP_005320465.1|2091364_2092474_-|PilT/PilU-family-type-4a-pilus-ATPase
MNLDALLAELVARKGSDLFITVGTPPTLKINGHLVSLGSEALDKQSALTLVRETLSPEHFERYIRTREGNYAIHREALGRFRVSAFWQQELPGMVVRRIETRIPTFDELTLPPILQEVAMAKRGLVLFVGATGTGKSTTQAAMIGYRNQNADGHILTVEDPVEFVHQHGRSLITQREVGIDTESFDVALKSSLRQAPDVILIGEIRSQETMEFALQFAETGHLCLATLHANNANQALDRILHLVPQEKHRQLLFDLSFNLRAIVAQQLVPSLDGRRRFAAFEVLLNTPLITDIIRKGEVHRLKEVMTKSTELGMQTFDQALFTLFCAGQIGYSEALAHADSANDLRLLIKLSGREQMGAGTLDNVTLDE
>NZ_CP047374.1|WP_005320464.1|2090559_2091333_-|peroxide-stress-protein-YaaA
MLIVVSPAKTLDYESPLVISRFTQPQLLDHSAELITRARQLSPDQIASLMKISDKLAGLNAARFAQWQHDFHPDNARQALLAFKGDVYTGLAVEDFSDGDFDFAQAHLRMLSGLYGVLRPLDLMMPYRLEMGTRLDNSRGKDLYQFWGDVITQHINAALTAQGDEVLINLASDEYFKSVRPKALKGRIVTPVFKDEKNGQFKIISFYAKKARGMMARHIIKHRLTEVEQLTGFNVDGYYFVPEESDAHTLMFKRAEN
>NZ_CP047374.1|WP_005320462.1|2089147_2090371_+|ATP-dependent-RNA-helicase-SrmB
MSQSFDDFDLHPALNRALAEMGFTRPTTIQQMVLEPALDGRDILASAPTGTGKTAAFVLPALQHLLDFPRRKPGPCRMLILTPTRELALQVTAHAKALAVHTNLSIETIIGGVSHEEQLPALTKTTDIVVATPGRLLEYIDKEEFESHDIEVLVLDEADRMLDMGFVKDVNRIVAEARYRKHTMLFSATLEGAGLEKFANEILNEPVELHAEPPRSERRPITQWVHLADDAAHKLALLIHILKDPETQKAIVFVRTRERLAELSGQLQAAGIPCAWIRGEMEQSKRVESIRKFHAGEVPFLVATDVAARGIDLPNVSHVINYDMPYGTDVYVHRIGRTGRAGNRGCAISLVEAHDMGMVAKIERYTEERLKRRVIDELRPKHKEARVPVKKKKPKDGKKKSAKKKKK
>NZ_CP047374.1|WP_017412061.1|2088308_2089019_-|methyltransferase
MGRNSGFTFKQFHVEHDRCAMKVGTDGILLGAWAPVAETRRVLDIGTGSGLVALMLAQRSRSDCIIDAVELDMNAATQARENVAASPWETRINIMEGAIQDYQATPYDLIVSNPPYFGAGQSLRDPARALARHTGSLDSRDLLAACDRLLTPVGQVALVLPTAMADEILCISADYDLHGVCYTAVITRAGKEANRVLLLLGRGLNRCEQGEIVIHSAGGAYSDRYIQLTHPFYLKM
>NZ_CP047374.1|WP_159364836.1|2086809_2088117_-|branched-chain-amino-acid-transport-system-II-carrier-protein
MTKSLTLSDVLGLGFMTFAFYLGAGNIIFPPLAGYMAGEHLSLAMLGFLVTAVGLPLITIIAVAKAGNGWAGMTKFLPAGLATALAVAIYIIIGPAFAAPRTGLVAYEMGLKPFIGDMGQAGLAAYTVIFFGIAILVSLNQGKLMDTIGKYLMPVLMVLLLTLAVGVFVAPQGTIPSATGDYLEGPFVKGILEGYNTMDTLASLMFGALIIDLLRQKGINDYKSQFKYLAIAGLISAIGLSVVYVSLFQLGNTAAGVATDVSNGGAIVNAYVLSLFGQPGQFILAGIITLACFTTAVGLISACSDFFHNLTGMSYKKLVVLLGTICAIVANVGLSQLISLSIPVLVAIYPVAVALVLVTFLKGYFGRPRLAFRSVLMVAFLFGCLDGLGAAGMKIDAFAFLPLFDKGLAWLLPTLLACGLGMAVRSSEKLAAEAA
>NZ_CP047374.1|WP_085941509.1|2086470_2086734_+|hypothetical-protein
MPPSKSVSSNAMWKALKWLFIGWVLLLILSDVQISTSLYKYDDNKVVVSFPRWQADRPWGTFQWHAGRIETHWYGLEGKPKPIVPLL
>NZ_CP047374.1|WP_005320452.1|2086037_2086499_+|chemotaxis-protein-CheX
MKADFVNPFLLSLLNVLSTMAQLELRPGKPKRKMDELARGDVSGLIGMVGPQTRGSLSISFEKGLALEIMRRMLGEAPATINEEVTDMVGEITNMVTGGAKRMLGEKGYEFDMATPIIVSGPNHTITHRADGTKIMMPFESDYGRATIEICFE
>NZ_CP047374.1|WP_005320451.1|2085589_2086048_+|zinc-uptake-transcriptional-repressor-Zur
MNQDQLLQRAERLCEQRGIRFTPTRRQVFTLLAAHGNAISAYDLLAQLQQTEAHAKPPTVYRALDFLLEQGFAHKVESLNAFIFCCHFDHAHPMQLLICDECGDVVELHDTAIDSAFSEQAHQHGFTITNKTIEAHGQCARCTPTVGSQHEG
>NZ_CP047374.1|WP_159364837.1|2095228_2095780_+|YggT-family-protein
MNTAYFLINTIFDIYLMVVLLRVWLQWARADFYNPMSQMVVKVTNPLVMPLRRVIPGFGGVDMASVLLAIIIAFAKLALLKSMNVLLADWLTISLFAALTVLKKAGSMIFWVLLIRAILSWVSQGRNPIEHVMHQLTEPFLAPIRRILPALGGLDLSVLVAFIGLQAINYLLGDLFGQLWWMI
>NZ_CP047374.1|WP_005320479.1|2095779_2096079_+|YggU-family-protein
MPAVLREGDELILHLMIQPKASRDQIVGLHGDELKVAITAPPVDGQANSHLIKYLAKQFKVAKGQVRIVRGELGRHKTVAIESPRQIPAEIHALLETQG
>NZ_CP047374.1|WP_005320482.1|2096097_2096517_+|DUF4426-domain-containing-protein
MKTAWISCLLALLMTLPLRAEQMKELGPWQVHYSAFNSSFLTPDVAKAYGLERSRYNGIINIAVQNKQGVAQAVGITGEAKNLTGTLRTLTFQEVKEGDAIYYLAVLPYRNQDTYQFTLKIMGEGQQQTLTFQQTFYVD
>NZ_CP047374.1|WP_011899099.1|2096585_2096885_-|hypothetical-protein
MRFLLMIPLLVTLPAHAASESQCRQAFTDWMLTQHQQFSDRNASKMKRRLAERAIDQMRDEFAKQESFCQAMEWATHHQDQDPRFNPRPGEIHDFTPAS
>NZ_CP047374.1|WP_159364838.1|2096994_2098599_-|oligopeptide-ABC-transporter-substrate-binding-protein-OppA
MKGWSPLLALLGCACVQAADVPPRTQLAAEQAVVRHLKDEPASLSPLKLVGLPELQVLRDLYEGLLTQGPDGKVLPGVATRWDNKDNQQFTFHLRPDARWSNGDKVKAADFVYGWRKLVDPKEAATFAWFAQLAHFTKVDEIVAGKLPPEALGVKALDEHTLQVTLSQPVPYFLSLLTHPTLSPLHQASMEKYGNQWTQPGKLVGNGAFVLSQRVVNEKLELAPNPHYWDRAHTVLTKVTFVPINQETAATNRYLAGDLHITESFPKEQYHKLMQQIPGEVHTPDQLGTYYYAFNTQLPPLNDVRARKALSYTIDRGLIAAKVLGTGEKPAYRFTPDVTADFEPKANLLSSTSQQDLDARARVLLQEAGYGPAKPLKLTLLYNTAEIHKKMALAIANLWKQKLGAQVELTNQEWKTYLDSRQSGQFEVIRSSWVADYNDPSAFLGLWGSRHSGNMARFANARYDEILTQAAKSRDPGERARLFDEAESILQDEAPIAPIYQYTNARLIKPWLKGYPINNPEDVAYSRQLYLIKH
>NZ_CP047374.1|WP_005320489.1|2098780_2099488_+|chromosome-partitioning-protein-ParB
MRAWILLALAISQGAWALAPCERETQVGSWCEVNIDQLHPTQGGVGQIQVDNTQAELAGKSEKQLDKVMKKKEIPIVIAPDGGYWLVDRHHLTKALWQLGVKQARVKVIARLQDKSSFWSQMQGNHWAWLKDEKGAPLTPEQLPVHIGDLPDYPYRTVAGMLQDAGYFEKRDQVYFVEFAWASWLGQQLNWLPVDGASLMERLNQAKRLACSSKASDLPGYPGKQCRVNQSRSGS
>NZ_CP047374.1|WP_005320492.1|2099535_2100198_-|CatB-related-O-acetyltransferase
MKHCQHWSQVEYLHLTVTNPNISLKGQHSYYSGAWDGPFEEEAVRYLHGDSWSRSPDTGWEPLWHIDRLHIGDYVQIAAGVKIIMGGNHTHNPAFISTYPFADPDALKRSYRPAGDTRIGNDVWIGMDAMIMPGVTIGDGAIIAARSLVTQDVPPYCMVAGAPARVIRQRFAVQETTRLQALAWWDWPDEQVQALLPLIQQGEVALLEQAAARWHSAEQE
>NZ_CP047374.1|WP_005320494.1|2100503_2100932_+|DUF2753-family-protein
MTHHIWQRYMLEAENALGAGALGAAICLYQQALAEVYELASDDLDELASMRVATCHRLADFWRAMEEPAYELRYLKLASELVTALVPQCPNRECESLVSELGCCQAALISFLKRHPNPEIARLIQLQDKVQGCELIGRFRLN
>NZ_CP047374.1|WP_085941508.1|2100935_2101715_-|enoyl-CoA-hydratase
MAACDNKDLDMDPIIVAEQQDGLLTLTFNRPDKRNALNTDMYRALTQALRQATQDDAVHALLIQGQSDCFTAGNDLADFMGKSSLDADDPILQFLHTLADFPKPVIAAVGGPAVGIGTTLLLHCDLVYLGDNARLQLPFVELGLVPEFASSLLLPRAVGHLKAAELLLLAEAIDADEALRLGLANRVVAADELLALARDQGLKLAAKPPKALQKSKALLKQELKQAVHFVIDLEARAFSLALQGEEAQHRIAQRLKPRA
>NZ_CP047374.1|WP_005320497.1|2101774_2102215_+|copper-chaperone-PCu(A)C
MFKRAFYSLLALGLAAPALAKVEAVDGYVRLLPPGSPNTAAFLVLKNDADKPVKLVAAASPEVGRAELHTHLHENGVMRMRQVESIAIPAKGEVALKPGSFHVMLFEVRELSQGTPFPLTLTMDDGQTLELSLPVKPIEPMAGMQH

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Crispr_ID: NZ_CP047374_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047374_5

2535717-2535815

Orphan

Consensus_repeat	Method
GCATAAAGATTGAACTATCGGTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP047374_5

>merge|NZ_CP047374|5|2535717-2535815|CRISPRCasFinder
GCATAAAGATTGAACTATCGGTTTGGGGCCTATGGTCTTGACCCTTAGGCGACAATGGCCGCTGGCCGAATCAGCAGCATAAAGATTGAACTATCAGTT

>NZ_CP047374|5|5|2535717-2535815|CRISPRCasFinder
GCATAAAGATTGAACTATCGGTT	TGGGGCCTATGGTCTTGACCCTTAGGCGACAATGGCCGCTGGCCGAATCAGCA
GCATAAAGATTGAACTATCAGTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047374.1\|WP_005318369.1\|2539400_2540825_-\|magnesium-transporter	unknown	unknown	gnl\|CDD\|225148
NZ_CP047374.1\|WP_085941392.1\|2543682_2546262_-\|nitrite-reductase-large-subunit	unknown	unknown	gnl\|CDD\|184951
NZ_CP047374.1\|WP_005318371.1\|2540975_2542382_-\|uroporphyrinogen-III-C-methyltransferase	unknown	unknown	gnl\|CDD\|182606
NZ_CP047374.1\|WP_005318375.1\|2543258_2543576_-\|nitrite-reductase-small-subunit-NirD	unknown	unknown	gnl\|CDD\|181921
NZ_CP047374.1\|WP_005318362.1\|2536845_2537331_-\|ribonuclease-E-activity-regulator-RraA	unknown	unknown	gnl\|CDD\|236487
NZ_CP047374.1\|WP_005318373.1\|2542394_2543207_-\|nitrite-transporter-NirC	unknown	unknown	gnl\|CDD\|183200
NZ_CP047374.1\|WP_011898246.1\|2525092_2526178_+\|polyamine-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270377
NZ_CP047374.1\|WP_005318337.1\|2528307_2529150_+\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|182574
NZ_CP047374.1\|WP_005318348.1\|2531670_2533494_+\|ATP-dependent-DNA-helicase-RecQ	unknown	unknown	gnl\|CDD\|182933
NZ_CP047374.1\|WP_011898245.1\|2523879_2524977_+\|polyamine-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270377
NZ_CP047374.1\|WP_005318352.1\|2533595_2533898_-\|c-type-cytochrome	unknown	unknown	gnl\|CDD\|225418
NZ_CP047374.1\|WP_005318359.1\|2535899_2536574_+\|7-cyano-7-deazaguanine/7-aminomethyl-7--deazaguanine-transporter	unknown	unknown	gnl\|CDD\|183041
NZ_CP047374.1\|WP_042468409.1\|2526254_2527409_+\|polyamine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|183226
NZ_CP047374.1\|WP_159364900.1\|2547630_2549025_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340879
NZ_CP047374.1\|WP_159364899.1\|2537476_2539330_+\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|223910
NZ_CP047374.1\|WP_005318334.1\|2527405_2528311_+\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|182646
NZ_CP047374.1\|WP_042468281.1\|2546519_2547440_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176149
NZ_CP047374.1\|WP_005318344.1\|2530420_2530948_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047374.1\|WP_005318340.1\|2529195_2529900_+\|MOSC-domain-containing-protein	unknown	unknown	gnl\|CDD\|225167
NZ_CP047374.1\|WP_085941554.1\|2531072_2531528_-\|thioesterase-family-protein	unknown	unknown	gnl\|CDD\|183276

Protein	Function_ID	Function_description	E-value
NZ_CP047374.1\|WP_005318369.1\|2539400_2540825_-\|magnesium-transporter	gnl\|CDD\|225148	COG2239, MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism].	2.62756e-151
NZ_CP047374.1\|WP_085941392.1\|2543682_2546262_-\|nitrite-reductase-large-subunit	gnl\|CDD\|184951	PRK14989, PRK14989, nitrite reductase subunit NirD; Provisional.	0
NZ_CP047374.1\|WP_005318371.1\|2540975_2542382_-\|uroporphyrinogen-III-C-methyltransferase	gnl\|CDD\|182606	PRK10637, cysG, siroheme synthase CysG.	0
NZ_CP047374.1\|WP_005318375.1\|2543258_2543576_-\|nitrite-reductase-small-subunit-NirD	gnl\|CDD\|181921	PRK09511, nirD, nitrite reductase small subunit NirD.	2.85715e-69
NZ_CP047374.1\|WP_005318362.1\|2536845_2537331_-\|ribonuclease-E-activity-regulator-RraA	gnl\|CDD\|236487	PRK09372, PRK09372, ribonuclease E inhibitor RraA.	3.36801e-99
NZ_CP047374.1\|WP_005318373.1\|2542394_2543207_-\|nitrite-transporter-NirC	gnl\|CDD\|183200	PRK11562, PRK11562, nitrite transporter NirC; Provisional.	8.02409e-174
NZ_CP047374.1\|WP_011898246.1\|2525092_2526178_+\|polyamine-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270377	cd13659, PBP2_PotF, The periplasmic substrate-binding component of an ABC putrescine transport system and related proteins; contains the type 2 periplasmic-binding fold. This group represents the periplasmic substrate-binding domain that serves as the primary polyamine receptor of ABC-type putrescine-preferential transporter from gram-negative bacteria. Polyamine transport plays an essential role in the regulation of intracellular polyamine levels which are known to be elevated in rapidly proliferating cells and tumors. Natural polyamines are putrescine, spermindine, and spermine. They are polycations that play multiple roles in cell growth, survival and proliferation, and plant stress and disease resistance. They can interact with negatively charged molecules, such as nucleic acids, to modulate their functions. Members of this family belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	0
NZ_CP047374.1\|WP_005318337.1\|2528307_2529150_+\|ABC-transporter-permease-subunit	gnl\|CDD\|182574	PRK10592, PRK10592, putrescine transporter subunit: membrane component of ABC superfamily; Provisional.	3.45474e-117
NZ_CP047374.1\|WP_005318348.1\|2531670_2533494_+\|ATP-dependent-DNA-helicase-RecQ	gnl\|CDD\|182933	PRK11057, PRK11057, ATP-dependent DNA helicase RecQ; Provisional.	0
NZ_CP047374.1\|WP_011898245.1\|2523879_2524977_+\|polyamine-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270377	cd13659, PBP2_PotF, The periplasmic substrate-binding component of an ABC putrescine transport system and related proteins; contains the type 2 periplasmic-binding fold. This group represents the periplasmic substrate-binding domain that serves as the primary polyamine receptor of ABC-type putrescine-preferential transporter from gram-negative bacteria. Polyamine transport plays an essential role in the regulation of intracellular polyamine levels which are known to be elevated in rapidly proliferating cells and tumors. Natural polyamines are putrescine, spermindine, and spermine. They are polycations that play multiple roles in cell growth, survival and proliferation, and plant stress and disease resistance. They can interact with negatively charged molecules, such as nucleic acids, to modulate their functions. Members of this family belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	0
NZ_CP047374.1\|WP_005318352.1\|2533595_2533898_-\|c-type-cytochrome	gnl\|CDD\|225418	COG2863, COG2863, Cytochrome c553 [Energy production and conversion].	5.31089e-25
NZ_CP047374.1\|WP_005318359.1\|2535899_2536574_+\|7-cyano-7-deazaguanine/7-aminomethyl-7--deazaguanine-transporter	gnl\|CDD\|183041	PRK11212, PRK11212, 7-cyano-7-deazaguanine/7-aminomethyl-7-deazaguanine transporter.	1.30694e-130
NZ_CP047374.1\|WP_042468409.1\|2526254_2527409_+\|polyamine-ABC-transporter-ATP-binding-protein	gnl\|CDD\|183226	PRK11607, potG, putrescine ABC transporter ATP-binding subunit PotG.	0
NZ_CP047374.1\|WP_159364899.1\|2537476_2539330_+\|HAMP-domain-containing-protein	gnl\|CDD\|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	1.2198e-71
NZ_CP047374.1\|WP_005318334.1\|2527405_2528311_+\|ABC-transporter-permease-subunit	gnl\|CDD\|182646	PRK10683, PRK10683, putrescine transporter subunit: membrane component of ABC superfamily; Provisional.	4.78085e-152
NZ_CP047374.1\|WP_042468281.1\|2546519_2547440_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176149	cd08460, PBP2_DntR_like_1, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator similar to DntR, which is involved in the catabolism of dinitrotoluene; contains the type 2 periplasmic binding fold. This CD includes an uncharacterized LysR-type transcriptional regulator similar to DntR, NahR, and LinR, which are involved in the degradation of aromatic compounds. The transcription of the genes encoding enzymes involved in such degradation is regulated and expression of these enzymes is enhanced by inducers, which are either an intermediate in the metabolic pathway or compounds to be degraded. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.19251e-87
NZ_CP047374.1\|WP_159364900.1\|2547630_2549025_+\|MFS-transporter	gnl\|CDD\|340879	cd17321, MFS_MMR_MDR_like, Methylenomycin A resistance protein (also called MMR peptide) and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of bacterial, fungal, and archaeal multidrug resistance (MDR) transporters including several proteins from Bacilli such as methylenomycin A resistance protein (also called MMR peptide), tetracycline resistance protein (TetB), and lincomycin resistance protein LmrB, as well as fungal proteins such as vacuolar basic amino acid transporters, which are involved in the transport into vacuoles of the basic amino acids histidine, lysine, and arginine in Saccharomyces cerevisiae, and aminotriazole/azole resistance proteins. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. For example, MMR confers resistance to the epoxide antibiotic methylenomycin while TetB resistance to tetracycline by an active tetracycline efflux. MMR-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.17309e-42
NZ_CP047374.1\|WP_005318340.1\|2529195_2529900_+\|MOSC-domain-containing-protein	gnl\|CDD\|225167	COG2258, COG2258, Uncharacterized protein conserved in bacteria [Function unknown].	1.3159e-65
NZ_CP047374.1\|WP_085941554.1\|2531072_2531528_-\|thioesterase-family-protein	gnl\|CDD\|183276	PRK11688, PRK11688, thioesterase family protein.	6.82968e-82

>NZ_CP047374.1|WP_005318352.1|2533595_2533898_-|c-type-cytochrome
MQRWVYALPLLALAWGHLAKAADIEAGKAKAAVCAACHGVEGKALIPHYPHLAGQNHAYLVKQLKAFKDGSRQEPLMVPFMAPLTEADMENLAAFYASLK
>NZ_CP047374.1|WP_005318348.1|2531670_2533494_+|ATP-dependent-DNA-helicase-RecQ
MTVIAETLPDTPLALLQAVFGYQQFRPGQLEIIEQIVAGRDAMVLKPTGGGKSLCFQIPALLRPGLGVVVSPLISLMKDQVDSLRANGVAAIYINSALSREEMIQNFAAMRRGEIKLLYVSPERLLQHEFMDRLAELPLGLFAIDEAHCVSQWGHDFRPEYAALGRLKQWFPQVPVVALTATADEATRSDMLHRLELNDPFIHTASFDRPNIRYSLVEKFKAAEQLLRYVQSQKGNCGIVYCSSRNRVEEVAERLSRHGSKAAPYHAGLPLAQRQQTQDAFLKDDIEIVVATVAFGMGIDKPNVRFVVHYDIPKNIESYYQETGRAGRDGTPAEALLLYDPADIGRVRRLLDNIENPQQLQVEQYKLNVMAAFAEAQTCRRQVLLNYFGEYNDKPCGNCDICLDPPKSYDGTEDAQKALSCVWRVGQNFGVGYVVEVLRGSLNQRIKDHGHDKLSTYGIGKDQSHEYWMSVIRQLIHKGLLTQNITRNLVLQLTEASRPVLRGEMKLELAVPRLQPISSRKEKRNGLLDNANYDKRLFKELRGLRKQIAEDEEVPPYVVFNDATLVEMAQLMPMTEAEMLAINGVGHRKLERFGEAFMDLIIDYCRR
>NZ_CP047374.1|WP_085941554.1|2531072_2531528_-|thioesterase-family-protein
MLKKMALSGIANLFAERMPFNKLIGMQVTHYDFDKVELRIKMDDKLIGNPFHNILHGGVTASLLDVAGGMIVAASCIDELEDFSPNYLKERFSRLGTIDLRVDYLRPGRGNEFIATAHIIRAGSKVAVARMELHNEEGTHIAFGTGTYLVG
>NZ_CP047374.1|WP_005318344.1|2530420_2530948_-|hypothetical-protein
MSAKLATKPSRALLTQLESMLDEVQTPECRHWLEQELEGYSLCSHLPWYRIVACRQRGHFLDLKTGKYLTCHINSQTLSQRDLAQIQFIYAREPAAHYLLQRNSGIEPWPEQLLEDYQEQLIPGHLCLQAWHEPVSSLRSQLMEGIEHFISEYPKHAALQPQHSFKALRHQHWHI
>NZ_CP047374.1|WP_005318340.1|2529195_2529900_+|MOSC-domain-containing-protein
MRIFIFSGQGTELVPGLVSAINKQATTIPLWCGFGGLGGDEQSDPRHHGGPDRALHYYPADHYPWWHNWQTAMGLAAPRTPWQPAAFGENLSGLGLTEEQACIGDVYRLGEALIQISQPRSPCFKLNLRFGYPQLSQVMQLSVRCGWLLRVLEEGTVAPQETMELVDRPYPALTVKRTADILFNQVRHEADLLLLLENPALSPNWRQHAANWLEHGVVADWQRRLLGPAEFQFS
>NZ_CP047374.1|WP_005318337.1|2528307_2529150_+|ABC-transporter-permease-subunit
MKRFGFAKMMLWLGLLFIYLPMVIMVIYSFNSSKLVTVWGGWSLKWYFGLLDNKQLIGSVLRSLEIALYTAVAAVALGTVAAFVLTRIPHFRGRTLFGGMVTAPLVMPEVITGLSLLLLFVAMAQLVGWPAERGMLTIWIAHTTFCTAYVAIVVSARLRELDLSIEEAAMDLGAKPWKVFFLITIPMIAPSLAAGGMMSFALSLDDLVLASFVSGPGATTLPMEVFSAVRLGVKPEINAVASLILLSVSLFTFSSWYLMARAEKRRRAEIAMTTQMQAVA
>NZ_CP047374.1|WP_005318334.1|2527405_2528311_+|ABC-transporter-permease-subunit
MKALRRLKRLGGRQLVIGIPFFWLFLFFLLPFIIVVKISFAEADVAIPPYTDVVSWADNQLTILLNLGNYLLLQEDELYIAAYIGSLKIAFISTVLCLLIGYPMAYTIARANKETQTVLLLLIMMPTWTAILIRVYAWMGILSNNGLLNSLLMGIGLIDEPLQILNTNLAVYIGIVYSYLPFMVLPLYANLVKHDQSLLEAASDLGARNLTRFWRITVPLSKNGIIAGCMLVFIPVVGEFVIPELLGGPETLMIGKVLWQEFFNNRDWPVASALAVVMLAVLIVPIILFNRNQAKELEGKV
>NZ_CP047374.1|WP_042468409.1|2526254_2527409_+|polyamine-ABC-transporter-ATP-binding-protein
MAIASSAYKKALEGNQQRKEVLVKIDRVSKQFDETLAVDNVSHNIHKGEIFALLGGSGSGKSTLLRMLAGFERPTEGRLFLDGVDITDMPPYERPINMMFQSYALFPHMTVAQNIAFGLKQDGLPKAEVDARVEEMLKLVQMAQYARRKPHQLSGGQRQRVALARSLAKRPKLLLLDEPMGALDKKLRSQMQLELVEIIERVGVTCVMVTHDQEEAMTMAERIAIMHLGCIEQIGSPMDIYETPASRLVCEFIGNVNLFDGLLVEDEQDHATIACADLEQPIYVGHGISSRAENKKVTYALRPEKLLMSTQKPTEIEHPDFNWTKGEVYDIAYLGGHSVYHIQLPSGKIVQAFIANAERHGKRPTWDDQVFLYWEDDSGVVLQS
>NZ_CP047374.1|WP_011898246.1|2525092_2526178_+|polyamine-ABC-transporter-substrate-binding-protein
MHTTKTVTMTLALGLASLAHAAPVVHFYNWSDYIGETTLSDFQQATGIKTVYDVFDSNETLEGKLLTGRTGYDLVVPSNNFLAKQITAGAFQKLDPALLPNLVNLDPVLLKQLDKVDPGHQYAVPYLWGTNGIGYNVDKIKDVLGVDKIDSWAVIFEPENMQKLSRCGVAFLDSADEMIPAVLNYLGLDPNSHKPEDIKRAEEQLLKVRPYVTYFHSSKYIGDLANGDICVAAGFSGDILQAAARADEAGKGINIAYSIPKEGGNLWFDMMAIPADATNVKEAHALINYVLQPEVIAKVSNYVGYANPNAKAGEYMDESVRDDESVYPPQAVLERLYVQQAHPRAVQRLITRSWTKIKSGT
>NZ_CP047374.1|WP_011898245.1|2523879_2524977_+|polyamine-ABC-transporter-substrate-binding-protein
MSFKTGMIAASVALVMASTGAMANEKVLHVYNWSDYIAPETLENFQKETGIKVVYDVFDSNEVLEAKLLAGSSGYDIVVPSNPFLAKQIKAGVFQKLDKSKLSNWQNMDADLLKALEPSDPGNQYSIPYLWGTIGYAYNAEKVKTVLGKDAPVNSWDLVFKPENMAKLKECGVSFLDSPTEMLPAALQYLGFKPDSQKPDELKQAEALFLSIRPYTAYFHSSKYISDLANGNLCVAVGYSGDLQQSKARAAEANNGVALTYTIPKEGAGSFFDMIAIPADAKNAEAAHTFINYLMKPEVIASITNFVQFPNGNKAATPLVDEAIRTDPGIYPNAETLQKIYTFPDLPAKVQRLMTRSWTKIKSGK
>NZ_CP047374.1|WP_005318359.1|2535899_2536574_+|7-cyano-7-deazaguanine/7-aminomethyl-7--deazaguanine-transporter
MNLTPAQHRTALVRLSLFHILIIASSNYLVQLPITIFGFHTTWGAFSFPFIFLATDLTVRIFGAGLARKIIQTVMLPALTVSYVLSVLFFEGSFQGVGNLAEFNLFVARIALASFMAYLVGQFMDVVVFNRLRLLRAWWVAPAASTLFGNLVDTIAFFSIAFWRSTDPFMADHWVEIATVDYVFKLLISLGLFVPLYGVLLRYLSRKLVGEAGLAGLQTATRQA
>NZ_CP047374.1|WP_005318362.1|2536845_2537331_-|ribonuclease-E-activity-regulator-RraA
MEYNTSELCDIYQDMVDVLEPMLCSFGGRASFGGVITTVKCFESNGLIRELVKENGVGRVLLIDGGGSMRRALIDSDIATTAAENEWEGIVCYGCVREVDILEDLDIGIQALAAIPVGADSKDVGETDLPVNFGGVTFLPDDHLYADTTGVILSPEALDIE
>NZ_CP047374.1|WP_159364899.1|2537476_2539330_+|HAMP-domain-containing-protein
MLIRHKLILNTALVAVAMLVLSALFLYSSQVSRHLAEAQRNVDGLEIAMLNLRRAEKDFLIRKDLTFVERFNKELADFHTLNRTLSTDDNISVVHGELARLDQQMGLYGKAFNDLVSQQQTIGLGPEDGLYGRLRAAVHQVEEGLKQLDQQGLLVTMLQLRRAEKDFMLRSDIQYLERFQTLHKSFQDNLAALPEADRGKLEQASQQYRQDFVALVQGMQVLGLKEDEGLRNQMRDLVHQTEQGFAAVGQHIADELVRQTSRLNSLMLVCGGVIIVLIGVMSVLLGRSIDRPISRVNDTVNRIRQDNDLRLRIELKGADEMAQLAGNLDVMLGGFRHLIGDVKQSVHTLIEAADHLSSNVRRTSEGASRQLQETDQVATASTEMGSTIEEIARNTEQAANNAQATNIKAMEGRTAVENTVRQIRSLAGNLESSSREVAQLQKESETIGSVLDVIRGIAEQTNLLALNAVIEAARAGDQGRGFAVVADEVRSLAIRTQKSTQEIAGIISSLQKQTGSIVGMMATCREQGNSSSEQASTAGDLLGQITQNVTHIMDMSTQIAAAIEQQSLVANEVNRNVTNIRDIAQESSLMAEENAKSSHGLTEQAKLLHQAVAKYRV
>NZ_CP047374.1|WP_005318369.1|2539400_2540825_-|magnesium-transporter
MSHPVKNSAKQREKDRRRILTLLLADDALTDSLLDPQSAQDAAQRDQTGEIIRLVNRLPAADVADTLESLPPDERHALWQLVNEEKHGQILVEASETVWDSLINGMSDKALLHALRSLDIDDQIYLGQYLPRNLMGRLLTSMAPPQRDRVRDVIRYGKHTVGAMMDFEIITVRAEVSLATVQRYLRLRAKIPVNTDKLFVIDRRNRLQGELPLTTLLLHKPDTLVANVMERDPVTFDPEDNDEAAARTFERDDLISAAVVDAKGKLMGRLTVAEVVDLVYEESDTDLRRMGGISEDEDLFAPVSKAVKTRWAWLAINLCTAFVASRVIGLFEHTISQLVALAALMPIVAGIGGNTGNQTITMIVRALALQHIQAGNISFLLWRELGVALVNGLVWGGTMGVATYLLYQDPALGAVMTLAMMINLLVAALMGVMIPMTMTRLGRDPAIGASVMITAITDTGGFFIFLGLATLFLI
>NZ_CP047374.1|WP_005318371.1|2540975_2542382_-|uroporphyrinogen-III-C-methyltransferase
MDYLPIFCRLDNKPVLLVGGGEVAERKARLLLDAGARLTVVSPALDPELAALATSGTIDWLAAEFEPAHLTGKWLVVAATDRREVNALVYQSANQAGIFANVVDDPKRSSFIMPSIIDRSPLMVAISSGGKAPVLARLLREKLEALLPQHLGAVAAFAGGLRARVKARFASMGERRQFWERLLSADRLGQALARGDKASANQLADTLFAEETGAKGEVILVGAGPGDPGLLTLHALRHMQQADLVVYDQLVSDEVMALVRRDARRIFVGKQAGNHCVPQEGINQLLLEEASKGQRVVRLKGGDPFIFGRGGEELETLVGSGVGFQVVPGITAASGCAAYAGIPLTHRDHAQSVRFVTAHGKGGTQDLDWPLLARDQQTLVFYMGLSSCATIRQKLTAHGKAGTTPVALIERGTQLNQRVIRGTLDQLPELAVGVESPALIMVGSVVTLADKLAWFGQTNHGVQAAALA
>NZ_CP047374.1|WP_005318373.1|2542394_2543207_-|nitrite-transporter-NirC
MYTETINKCAANAARINRFERSDKLGFWLSSAMAGAYVGLGIILIFTLGNLVDPSIRPLVMGATFGIALTLVIIAGSELFTGHTMFLTFGVKTGKITMTDLLRILPQTWAGNLLGSIAVALIYSYGGSLLPDAGSLAHKVALAKTQAPALTLFMKGILCNWLVCLAIWMALRTEGAAKFIAIWWCLLAFIASGYEHSVANMTLFALSWFGAHSEAYTLGGIGHNLLWVTLGNTVSGALFMGLGYWYATPKADRPVAVTDANAAASQTQTA
>NZ_CP047374.1|WP_005318375.1|2543258_2543576_-|nitrite-reductase-small-subunit-NirD
MKFACQLNDILPGTGVCALIEGRQIALFRPSAAAEVFAIDNRDPFFAANVLSRGLICEHEGALWVASPLKKQRFRLSDGHCFENPAMSIASYAVEVRDQQVWVAV
>NZ_CP047374.1|WP_085941392.1|2543682_2546262_-|nitrite-reductase-large-subunit
MMFYYSKLEAIMSKVRLAVIGNGMVGHRFIEELIERADPDRFEITVFGAEPRPAYDRVHLSSYFSHHTSEDLSLVKPGFYEKHGIRLLLGEAVKKIDRAAREVHSNKGTVVGYDKLVLATGSYPWVPPIAGSQHHECFVYRTIEDLKAIRSAAKSGKSGVVIGGGLLGLEAAGALKALGLETHVVEFAPVLMAEQLDGQGGQLLRRKIESMGVQVHTSKSTSEILMHGGRDAQHRLAFADGSTLEVDVVVFSTGIRPQDTLGRYSELAIAERGGVAVDDHCLTSDPDIYAIGECAAWQGRFFGLVAPGYKMAQITVDHLLGGDSRFEGADMSAKLKLLGVSVGSIGDAHGRTPGSHSYVFQDDQAGVYKRIVVSEDNSRLLGAVLVGDVDDYGNLLQLMLNAMPLPAHPDTLILPAYAGAKPTLGVDALPSTAQICSCFDVSKGDIAQAVAEGHTTLAAIKQHTKAGTGCGGCVPLISQVLNAELVKQGIEVNNHLCAHFPHSRQELFHLVKVEGIKSFNELLARHGHGYGCEVCKPTVGSILASCWNGYVLNPLNTQLQDTNDIFLGNMQKDGSYSVIPRMAGGEVTPEGLLAVAEVARDYKLYTKITGAQRIGLFGAQKDDLPAIWRKLLAAGFETGQAYAKALRMAKTCVGSTWCRFGVQDSVGLGVFLENRYKGIRTPHKMKFGVSGCTRECAEAQGKDVGIIATDAGWNLYVGGNGGMKPRHADLLASDLDRETLIKLIDRFMMFYVTSADKLQRTSVWLGNLEGGVDYLREVIVDDKLGLNATLERDIQVLIDSYECEWSRTLNEEEQLKRFSHFINSGKRDPDVQFVSERDQHRPATPAERIPVYQIEVEAK
>NZ_CP047374.1|WP_042468281.1|2546519_2547440_-|LysR-family-transcriptional-regulator
MTTPDFNLLLTLDALLDEGSVAGAARRLKLSPSAMSRALARLRDTTGDPLLVRAGRGLVPTPRALALRERVSQLVQEAEAVLRPQQEIDPAHLVRTFRLRSSDGFVESVGAALLARLAAEAPGVRLHFIAKPDKESHPLRSGELDFETGVIGTNTAPELRTQALFQDRFVAVVRPGHPLCEGPLTAVRYAAARHVLVSRRGQEHGPIDEALAALKLERAIATLVPGFATALALVRGSDLVATVPALHCASLHADLVTLPLPFPLPGITLALLWHPRLDADPAHRWLRTVIRETCARAPYQATQKER
>NZ_CP047374.1|WP_159364900.1|2547630_2549025_+|MFS-transporter
MSHSITIPTPFARRAGLLALGLATLVPMLAGSMANMVLPALGQVFAVPFASVQWVLVAYLLGITCLTVVAGRLGDRFGRRRLLLWGMALFALASLLCALAPTIGWLIAARVLQGAGAACMLSLALAMVGQLVPPERRGWSMGLLGTLSACGTALGPSFGGLLIGAFGWQAPFLLLVPVSLLALGAGMLGLPPEGALPQRERVNLASLSMLVMALLCYGLALTSGGILALGLWAGALLVTALFIRRERLDPSPLLPLVLLAEPRLRGGLLASALVASVMVVTLLIGPFYLRGVFDLDMATVGLMISRGPLLAALTGMPAGWLVDRFGVLWVVRLGLAVMVIAALGLATLTAGYGPLGYLLPILLLTAGYALFQTANNSAVVGGASEQARGAVAGLLTLSRNLGQLTGAAGLGGLFATLVGTHNLSMAMPTDLVFGTQVTFALTGLLTGLALWLVGRRREEALAVV

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Crispr_ID: NZ_CP047374_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047374_6

2839343-2839429

Orphan

Consensus_repeat	Method
TATTCCAACCTGATCCGAACCCT	CRISPRCasFinder

1 spacers

WYL

The CRISPR arrays of NZ_CP047374_6

>merge|NZ_CP047374|6|2839343-2839429|CRISPRCasFinder
TATTCCAACCTGATCCGAACCCTCTCTTCCTGATATGACGGTGAGTGGACAGATGCAGCGCGAATATTCCAACCTGATCCGAAACCT

>NZ_CP047374|6|6|2839343-2839429|CRISPRCasFinder
TATTCCAACCTGATCCGAACCCT	CTCTTCCTGATATGACGGTGAGTGGACAGATGCAGCGCGAA
TATTCCAACCTGATCCGAAACCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047374.1\|WP_005319532.1\|2846544_2846958_+\|Hsp20-family-protein	unknown	unknown	gnl\|CDD\|182691
NZ_CP047374.1\|WP_159364233.1\|2849218_2850466_-\|valine--pyruvate-transaminase	unknown	unknown	gnl\|CDD\|236517
NZ_CP047374.1\|WP_005319511.1\|2848674_2849106_-\|type-III-secretion-protein	unknown	unknown	gnl\|CDD\|341102
NZ_CP047374.1\|WP_005319547.1\|2836934_2837693_-\|amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270427
NZ_CP047374.1\|WP_005319534.1\|2845561_2846266_-\|YafY-family-transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|225253
NZ_CP047374.1\|WP_005307156.1\|2835114_2835249_-\|50S-ribosomal-protein-L34	unknown	unknown	gnl\|CDD\|366117
NZ_CP047374.1\|WP_042467190.1\|2847051_2847489_+\|Hsp20-family-protein	unknown	unknown	gnl\|CDD\|182691
NZ_CP047374.1\|WP_005319540.1\|2841663_2844078_+\|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-B	unknown	unknown	gnl\|CDD\|237860
NZ_CP047374.1\|WP_005319562.1\|2830138_2831338_+\|histidine-decarboxylase	unknown	unknown	gnl\|CDD\|235068
NZ_CP047374.1\|WP_159364936.1\|2834755_2835115_-\|ribonuclease-P-protein-component	unknown	unknown	gnl\|CDD\|179327
NZ_CP047374.1\|WP_011899267.1\|2836265_2836934_-\|amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836
NZ_CP047374.1\|WP_017411496.1\|2844145_2844910_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP047374.1\|WP_005319551.1\|2835518_2836253_-\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NZ_CP047374.1\|WP_034281998.1\|2845113_2845491_-\|drug:proton-antiporter	unknown	unknown	gnl\|CDD\|319922
NZ_CP047374.1\|WP_005319560.1\|2831439_2832801_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	unknown	unknown	gnl\|CDD\|235392
NZ_CP047374.1\|WP_005319556.1\|2834540_2834789_-\|membrane-protein-insertion-efficiency-factor-YidD	unknown	unknown	gnl\|CDD\|376620
NZ_CP047374.1\|WP_005319542.1\|2839457_2840561_+\|DNA-polymerase-III-subunit-beta	unknown	unknown	gnl\|CDD\|235541
NZ_CP047374.1\|WP_017411499.1\|2832888_2834535_-\|membrane-protein-insertase-YidC	unknown	unknown	gnl\|CDD\|234942
NZ_CP047374.1\|WP_159364232.1\|2840563_2841667_+\|DNA-replication/repair-protein-RecF	unknown	unknown	gnl\|CDD\|234608
NZ_CP047374.1\|WP_005319564.1\|2829747_2829999_+\|isochorismatase	unknown	unknown	gnl\|CDD\|225967

Protein	Function_ID	Function_description	E-value
NZ_CP047374.1\|WP_005319532.1\|2846544_2846958_+\|Hsp20-family-protein	gnl\|CDD\|182691	PRK10743, PRK10743, heat shock chaperone IbpA.	7.51216e-68
NZ_CP047374.1\|WP_159364233.1\|2849218_2850466_-\|valine--pyruvate-transaminase	gnl\|CDD\|236517	PRK09440, avtA, valine--pyruvate transaminase; Provisional.	0
NZ_CP047374.1\|WP_005319511.1\|2848674_2849106_-\|type-III-secretion-protein	gnl\|CDD\|341102	cd17019, T3SC_IA_ShcA-like, Class IA type III secretion system chaperone protein, similar to Pseudomonas syringae chaperone protein ShcA. This family includes type III secretion system (T3SS) chaperone proteins similar to Pseudomonas syringae ShcA and similar proteins. In P. syringae, which is a plant pathogen that can infect a wide range of species, the T3SS allows injection of the effector HopA1 (previously known as HopPsyA or HrmA), a protein that has unknown functions in the host cell but possesses close homologs that trigger the plant hypersensitive response in resistant strains. Chaperone ShcA binding to Hop1A shows that interactions in animal pathogens are preserved in the Gram-negative pathogens of plants.	4.00151e-38
NZ_CP047374.1\|WP_005319547.1\|2836934_2837693_-\|amino-acid-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270427	cd13709, PBP2_YxeM, Substrate binding domain of an ABC transporter YxeMNO; the type 2 periplasmic binding protein fold. This group contains cystine-binding domain (YxeM) of a periplasmic receptor-dependent ATP-binding cassette transporter and its closely related proteins. Cystine is an oxidized dimeric form of cysteine that is required for optimal bacterial growth. In Bacillus subtilis, three ABC transporters, TcyJKLMN (YtmJKLMN), TcyABC (YckKJI), and YxeMNO are involved in uptake of cystine. Likewise, three uptake systems were identified in Salmonella enterica serovar Typhimurium, while in Escherichia coli, two transport systems seem to be involved in cystine uptake. Moreover, L-cystine limitation was shown to prevent virulence of Neisseria gonorrhoeae; thus, its L-cystine solute receptor (Ngo0372) may be suited as target for an antimicrobial vaccine. The cystine receptor belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.03493e-124
NZ_CP047374.1\|WP_005319534.1\|2845561_2846266_-\|YafY-family-transcriptional-regulator	gnl\|CDD\|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	2.82005e-64
NZ_CP047374.1\|WP_005307156.1\|2835114_2835249_-\|50S-ribosomal-protein-L34	gnl\|CDD\|366117	pfam00468, Ribosomal_L34, Ribosomal protein L34.	1.68921e-12
NZ_CP047374.1\|WP_042467190.1\|2847051_2847489_+\|Hsp20-family-protein	gnl\|CDD\|182691	PRK10743, PRK10743, heat shock chaperone IbpA.	4.0303e-46
NZ_CP047374.1\|WP_005319540.1\|2841663_2844078_+\|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-B	gnl\|CDD\|237860	PRK14939, gyrB, DNA gyrase subunit B; Provisional.	0
NZ_CP047374.1\|WP_005319562.1\|2830138_2831338_+\|histidine-decarboxylase	gnl\|CDD\|235068	PRK02769, PRK02769, histidine decarboxylase; Provisional.	0
NZ_CP047374.1\|WP_159364936.1\|2834755_2835115_-\|ribonuclease-P-protein-component	gnl\|CDD\|179327	PRK01732, rnpA, ribonuclease P; Reviewed.	3.33425e-64
NZ_CP047374.1\|WP_011899267.1\|2836265_2836934_-\|amino-acid-ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	7.24137e-75
NZ_CP047374.1\|WP_017411496.1\|2844145_2844910_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	6.06486e-06
NZ_CP047374.1\|WP_005319551.1\|2835518_2836253_-\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	1.27833e-133
NZ_CP047374.1\|WP_034281998.1\|2845113_2845491_-\|drug:proton-antiporter	gnl\|CDD\|319922	cd07261, EhpR_like, phenazine resistance protein, EhpR. Phenazine resistance protein (EhpR) in Enterobacter agglomerans confers resistance by binding D-alanyl-griseoluteic acid and acting as a chaperone involved in exporting the antibiotic rather than by altering it chemically. EhpR is evolutionarily related to glyoxalase I and type I extradiol dioxygenases.	1.54675e-56
NZ_CP047374.1\|WP_005319560.1\|2831439_2832801_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	gnl\|CDD\|235392	PRK05291, trmE, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE.	0
NZ_CP047374.1\|WP_005319556.1\|2834540_2834789_-\|membrane-protein-insertion-efficiency-factor-YidD	gnl\|CDD\|376620	pfam01809, Haemolytic, Haemolytic domain. This domain has haemolytic activity. It is found in short (73-103 amino acid) proteins and contains three conserved cysteine residues.	5.96059e-39
NZ_CP047374.1\|WP_005319542.1\|2839457_2840561_+\|DNA-polymerase-III-subunit-beta	gnl\|CDD\|235541	PRK05643, PRK05643, DNA polymerase III subunit beta; Validated.	0
NZ_CP047374.1\|WP_017411499.1\|2832888_2834535_-\|membrane-protein-insertase-YidC	gnl\|CDD\|234942	PRK01318, PRK01318, membrane protein insertase; Provisional.	0
NZ_CP047374.1\|WP_159364232.1\|2840563_2841667_+\|DNA-replication/repair-protein-RecF	gnl\|CDD\|234608	PRK00064, recF, recombination protein F; Reviewed.	8.12337e-140
NZ_CP047374.1\|WP_005319564.1\|2829747_2829999_+\|isochorismatase	gnl\|CDD\|225967	COG3433, COG3433, Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism].	4.72789e-16

>NZ_CP047374.1|WP_005319547.1|2836934_2837693_-|amino-acid-ABC-transporter-substrate-binding-protein
MTSSIKLVSGAAILLAALSGQAIAQETIKVGMSGKYFPFTFVKQDKLQGFEVDMWNQIGERTGYKVEFVTASFSGLFGMLETGRVDTISNQITITDERKAKYAFSQPYVYDGAQIVVRKGNSTIHGIKDLEGKTVAVNLGSNFEELLRKNDPNKKIDIRTYDSSFEQDVALGRIDAFVMDRVSTAQLIKESKLPLQQAGAPFETIENALPFLKTPEKQALLKKVDDALTAMRKDGALRQISEKWFAADITDK
>NZ_CP047374.1|WP_011899267.1|2836265_2836934_-|amino-acid-ABC-transporter-permease
MMEFDLEYTLGLFPILLKYLGTTMEMALWGFVLALVLSLTLAIVRVFRIPVIHWLAMLYISFFRGTPLLVQLFLLYYGLPQLFPVFVGMDAFTAAIVGLTLHFAAYMAESIRAAILGIHKSQMEAALSIGMSRYQAMRRIILPQAARIATPSLMNYFIDMIKSTSLAFTLGVAEIMGKAQMEASSSFKFFESFMAVALVYWVVVIIFTRLQHLLEVHLNRAY
>NZ_CP047374.1|WP_005319551.1|2835518_2836253_-|amino-acid-ABC-transporter-ATP-binding-protein
MIKLTGLSKAFHGNKVLNSIDLEVRKGEIVVIIGPSGTGKSTLLRCLNLLETPDAGTLAIDDLQLDLANASEQQAIELRKRASFVFQNYALFANKTALDNIAEGLITVWKQPKAEARATALGILKDIGLADKQDAYPASLSGGQQQRVGIGRAMAAHSKVILFDEPTSALDPEWVDEVLGLMKELARQHQTMVVVTHEIEFARDVADRVIFMEGGRIVEQGPPDQILVDPKDPRTREFLRKVLK
>NZ_CP047374.1|WP_005307156.1|2835114_2835249_-|50S-ribosomal-protein-L34
MKRTFQPSNLKRKRSHGFRARMATANGRKVLAARRAKGRARLVV
>NZ_CP047374.1|WP_159364936.1|2834755_2835115_-|ribonuclease-P-protein-component
MPTPHTFSRELRLLTPEHFKRVFAEPVRVASPQITLLACPNTLEHPRLGLAVPKKALKRAVWRNRVKRVVRESFRLNQASLPAIDIVVIAKGGVKEMDNEELFKLLEKLWRTLSRRCNG
>NZ_CP047374.1|WP_005319556.1|2834540_2834789_-|membrane-protein-insertion-efficiency-factor-YidD
MAHSVTPLQWVAVKLIRLYQLIISPLLGQRCRFTPTCSQFAIEAIRLHGFIKGVWLASKRLLKCHPLSEGGYDPVPQPKRRN
>NZ_CP047374.1|WP_017411499.1|2832888_2834535_-|membrane-protein-insertase-YidC
MESQRNLILIGLLFVSFLLWQQWESDKAPKPAPTTVAQTEHFVPEAGQTGDIPQVSEQANANAARKLITVSSDVLKLTLDTQGGDIVSAELLAHKLEEGKDQSFVLLTSQPDRLYVAQSGLVGRDGPDSQAQGRPTYEAAQTSYQLADGQDQVVVPMTWTDSKGVVFTKEFVLKRGDYAIGVDYKIDNKSAEPVQVQFYGQLKQTVTTPKDQEGHAMVASAYRGGAFSSEESRYKKYTFDEMKDADLNKTTKGGWVAMLQHYFVSAWAPNADDTNSFYSRVIPGKDQAIIGYKAPLVDVAAGQQAEVTSKLWVGPKLQDQMAKVANHLDLTVDYGWLWFIAQPLHWLLTVFQGFVHNWGVAIIMLTLLVRGIMFPLTKAQYTSMAKMRMLQPKLAALKERFGDDRQKMSQGMMELYKKEKVNPLGGCLPILVQMPIFIALYWALMESVELRHAPFALWITDLSVKDPFFVLPILMGASMWYLQKMSPTTITDPMQQKVMQFMPIIFTFMFLWFPAGLTLYWLVSNVISITQQTIIYRQLEKKGLHTRT
>NZ_CP047374.1|WP_005319560.1|2831439_2832801_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE
MTTDTIVAQATAPGRGGVGIVRVSGPAAEQVAEIVLGKLPRVRYAEYLPFKDEQGQPLDQGIALLFKAPNSFTGEDVLELQGHGGPVIMDMLVRRILQIKGLRPARPGEFSERAFMNDKLDLAQAEAIADLIEASSEQAARSAMHSLQGQFSSKIQQLVESLIRLRIYVEAAIDFPDEEIDFLSDGKVAGDLYAIMAELDGVRSEAKQGALLREGMKVVIAGRPNAGKSSLLNALAGRESAIVTEIAGTTRDVLREHIHLDGMPLHIIDTAGLRDTLDKVEQIGIERAWAEIEQADRVLFMVDGTTTDAIDPREIWPEFVDRLPKDIGLTVVRNKADLTGEDLAPSQELGHAVYRISAKTELGLPALREHLKACMGFQGNTEGGFMARRRHLDALERAAERLLVAKDQLEIYVAGELVAEELRLAQESLSEITGEFSSDDLLGRIFSSFCIGK
>NZ_CP047374.1|WP_005319562.1|2830138_2831338_+|histidine-decarboxylase
MCRHACIALAMGMIMGLSSEDAGKIESFWRYCVQHQYFNIGYPEAADFDYSALNRFLNFSINNCGDWSQQSNYLLNSFDFEREVMQFFATLFCIPFEQSWGYVTNGGTEGNMFGCYLARELFPEATLYYSKDTHYSVAKIIRLLRVKSCMVDSLPNGEMNYDDLINRIRLDGERHPIIFANIGTTMTGATDNIATIQRRLKKIGITKGDYYLHADAALSGMILPFIDNPQPFSFADGVDSISVSGHKMIGSPIPCGIVLARRKHVEHVSVEIDYISACDQTISGSRNGYTPLLLWMAIKSRSFSDWRQRTQHCLDMAQYVIERFHAKGIHAWRNPNSITVVFPKPADHIWKKHCLATSGKISHIITMPHHTGKETLDRVINDIALDREPGRGLAHALTV
>NZ_CP047374.1|WP_005319564.1|2829747_2829999_+|isochorismatase
MTNPEMISHQWLQERVQQLIEDNDTELDLEESLILYGLDSLRVMRFAAELKERNIHVSFEDLIKSPTLASWRELIANRQAIAR
>NZ_CP047374.1|WP_005319542.1|2839457_2840561_+|DNA-polymerase-III-subunit-beta
MQLEISREALLRPLQLVSGALGGRPTLPILGNVLLDVSQGLLSLTGTDLEVEMIGQVYLNNESQDGRTTVPARKLLDICRGLPEGADIRLNTEGERLIIRSGRSRFNLSTLPASEYPNIEDWESVLEFDIGQLELKKLIDATQFSMASQDVRYYLNGMLFESEGHGLRTVATDGHRLATCRREVVEESLPDHQVILPRKGVLELVRLLEAEDKPVRLQIGRSNLRAALDGFIFTSKLVDGRFPDWRRVIPRNSDKALIAGREDLRQAFARAAILSNEKFRGVRLNLQENLLRITANNPEQEEAEELLDVQYEASEMEIGFNVSYVLDVLNTLKCDQIRISLSDSISSAIIEDFDHQDAQYVVMPMRI
>NZ_CP047374.1|WP_159364232.1|2840563_2841667_+|DNA-replication/repair-protein-RecF
MSLVKLQLSDFRNIQQASLKLSPGLNILVGCNGSGKTSVLEAIHYLGLGRSFRTHLTGRVIRQGEQAFTLFAQCELEGRQVPIGLAKDKSGETQLKIAGAQAQRLADLAELLPVQLIHPDGFNLLTGGPQARRAWLDWGVFHQEPTFFSLWGRVRRLLKQRNALLRQSTQYRQLAFWDQELVRLGGELAEFRASYCQAITPLIKEMTADFLPEFDISLGFYRGWEKDTPLGDLLEAGFERDRTLGYTGVGPQKADVRLKANGVPVQDILSRGQLKLLVCAMRLAQGLYLNQHSSRGCIFLIDDFASELDVDKRRLLATRLKQCGSQVFITAIDTGQLADMMDANDCKLFHVEQGKISETLEKAESKL
>NZ_CP047374.1|WP_005319540.1|2841663_2844078_+|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-B
MSENTYDSSNIKVLKGLDAVRKRPGMYIGDTDDGSGLHHMVFEVVDNSIDEALAGYCSDILVKIHSDGSVSVRDNGRGIPVDMHEEEGRSAAEVIMTVLHAGGKFDDNSYKVSGGLHGVGVSVVNALSDKLLLTIRRNGHVYEQTYHLGEPQAPLKQIGDSSSGTGTEVRFWPSPTIFTDTLYHYEILAKRLRELSFLNSGVSIRLQDERDGREVHFCYEGGIKAFVEYLNQNKTPIHPKVFHFSTEQDGIGVEVAMQWNDAYQEGVYCFTNNIPQRDGGTHLVGFRTALTRTLNTYMDKEDYSKKAKSAASGDDVREGLIAVISVKVPDPKFSSQTKDKLVSSEVKTAVEQAMGEKLGEFLLENPGDAKIVVNKIIDAARAREAARKARELTRRKGALDIAGLPGKLADCQEKDPALSELYIVEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMISSQEVGTLITALGCGIGRDEYNPDKLRYHNIIIMTDADVDGAHIRTLLLTFFYRQMPEIIERGYIYIAQPPLYKVKKGKQEQYLKDEDALLQYQTAMALDGATLHVNESAPPIGGEALERLVNQHRAVSHLITRMSRRAPDAVLTQLIYQPELNETLLASESDLLAWCQGMEAVLNESNHGIQYQIQVRRDEERSLFVPHAVVRQHGVDREYAISYDFLQSSEYRQLVSLGKEIANLIEDGGFIKRGEKVKPIANFVEAVDWLMGEGKRGIYIQRYKGLGEMNPDQLWETTMDPEARRMLRVTIDDAVGADQLFSTLMGDAVEPRRDFIETNALRVANLDV
>NZ_CP047374.1|WP_017411496.1|2844145_2844910_-|GNAT-family-N-acetyltransferase
MTSRHNSLRLYQPTNSTPDELTEQQLALFTLLQLREQEFGFNPNVIVHYPEAGFLGSPIGYLNQLIGEQLQQGYFINQVVILTTYQVLSSPLMQAGYQHEAVHMPAGPDHTAIFRWQCGTHPAGKTLYVEVVNEQDPKIRPTFVLMLRDEHGKLLGGMSGSIWTKEEHRYAYIGTVVVQPGQPAGTGTRLANTVLEYLSLQKVCEINLGTQTAEPFYTRLGFRAIHHIVPALRHRTTKDGTELPHNLVIMSKLL
>NZ_CP047374.1|WP_034281998.1|2845113_2845491_-|drug:proton-antiporter
MLVPQFTILYVANPARSALFYRELFGHPPVEESPTFAMFVFESGARLALWSSATVEPAVTQSAGAMELAFPLPNEASVDTGLAEWRARGLTILQQPTKMEFGYTGMALDPDGHRLRLYCPGAEPV
>NZ_CP047374.1|WP_005319534.1|2845561_2846266_-|YafY-family-transcriptional-regulator
MSRSERLLALLQLLRGHRYAITGTELASQLGISMRTLYRDIATLQAQGAHIEGEPGIGYVLRPGFMLPPLMFSEDELEALVLGSRWVVAHCDEALSASASSALAKIEAVLPAEYRQQLQANALLIGTSRSDSPVDEAPLRSAIRQQRKVTLSYRDLKEELSERTVWPFALGYFEQVRVLVAWCELRQGFRHFRVDRIAWMQLEDNRYPKSRESLLKEWRATQQIPQPKFIADRN
>NZ_CP047374.1|WP_005319532.1|2846544_2846958_+|Hsp20-family-protein
MRSIDFSPLYRSAIGFDRLANLIESAASNGNAGYPPYNIEQLSDNDYRISMAVAGFTQEELELSFQENLLTVKGSKQAESDRNYLYQGIAERGFERRFQLADYVRVKGADLKNGLLHIELMREVPEAMKPRKIEING
>NZ_CP047374.1|WP_042467190.1|2847051_2847489_+|Hsp20-family-protein
MRNLDFSHLYSNAVGFERMARELEGLFEQKAAAYPPYNIEKREHDSYRITLAVAGFEREELELETENGTLKVKGCKAAAGERQFLHQGIAERDFELAFKLSQHVEVQGAKLEHGLLTIDLARELPEALKPRAIEIGKPDQLALPG
>NZ_CP047374.1|WP_005319511.1|2848674_2849106_-|type-III-secretion-protein
MDIGEILLAELATQLQLSSLTIDENGNCPLLIDSELPLILHLEPCALLIMAPLVLPTFSFDNAELQRRMLMAALNPAFDKEPGIGWHPEFQLIAYRRHMLDGMTGSQLAQHLGDFIEWMRKFVTSLPRSTPATATTRGIHDRV
>NZ_CP047374.1|WP_159364233.1|2849218_2850466_-|valine--pyruvate-transaminase
MEFSLFGEKFTRHAGITQLMDDLNQGLTNPDAIMLGGGNPAPIPAMLERFQTEARNLLDNGELVKAMANYDGPQGKDRFTKALATLLSKELGWNITSRNIALTNGSQNAFFYLFNLLAGEFADGRKKKVLFPLAPEYIGYADSALADDYFVAYKPTIEKLPDGQFKYHVDFESLQVGDDIGVICVSRPTNPTGNVLTDEEIEHLDQIARDKGIPLLIDNAYGVPFPGIIFSEAKPFWNANTILCMSLSKLGLPGTRCGIVIADEKIIQAITNLSGIINLAPGSLGPAITIPMIESGEIIALSEQVVKPFYKQKADFAVQLLRDAIPDPRFHIHKPKGALFLWLWFEGLPIHSQELYERLKAKNLLIVPGHYFFPGIDDPEWRHSQECIRLNYSQSEELVRRGIAILADEINALYV

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Crispr_ID: NZ_CP047374_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047374_7

2921545-2921638

Orphan

Consensus_repeat	Method
GGAGAAACAGCTCGAGATTGCGAAGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP047374_7

>merge|NZ_CP047374|7|2921545-2921638|CRISPRCasFinder
GGAGAAACAGCTCGAGATTGCGAAGATCCATCTTTCTATTCCTGCGGCGGCGCGTTTGCTGGCGTGGGGGAGAAACAGCTTGAGATTGCGAAGA

>NZ_CP047374|7|7|2921545-2921638|CRISPRCasFinder
GGAGAAACAGCTCGAGATTGCGAAGA	TCCATCTTTCTATTCCTGCGGCGGCGCGTTTGCTGGCGTGGG
GGAGAAACAGCTTGAGATTGCGAAGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047374.1\|WP_159364243.1\|2903418_2904543_-\|5-(carboxyamino)imidazole-ribonucleotide-synthase	unknown	unknown	gnl\|CDD\|235674
NZ_CP047374.1\|WP_159364246.1\|2916794_2919365_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|223972
NZ_CP047374.1\|WP_102665385.1\|2919820_2920693_+\|transporter-substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|366132
NZ_CP047374.1\|WP_005321293.1\|2926810_2927407_-\|nucleoid-occlusion-factor-SlmA	unknown	unknown	gnl\|CDD\|181894
NZ_CP047374.1\|WP_005307500.1\|2930488_2930656_+\|50S-ribosomal-protein-L33	unknown	unknown	gnl\|CDD\|179075
NZ_CP047374.1\|WP_159364245.1\|2907626_2909462_+\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|236730
NZ_CP047374.1\|WP_159364247.1\|2921763_2923245_+\|ketol-acid-reductoisomerase	unknown	unknown	gnl\|CDD\|235368
NZ_CP047374.1\|WP_005321282.1\|2928079_2929282_-\|bifunctional-phosphopantothenoylcysteine-decarboxylase/phosphopantothenate--cysteine-ligase-CoaBC	unknown	unknown	gnl\|CDD\|235513
NZ_CP047374.1\|WP_005321271.1\|2930240_2930477_+\|50S-ribosomal-protein-L28	unknown	unknown	gnl\|CDD\|234736
NZ_CP047374.1\|WP_005321297.1\|2925473_2925662_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047374.1\|WP_005321295.1\|2925823_2926660_-\|mechanosensitive-ion-channel	unknown	unknown	gnl\|CDD\|182386
NZ_CP047374.1\|WP_159364244.1\|2905419_2906493_-\|sodium-dependent-bicarbonate-transport-family-permease	unknown	unknown	gnl\|CDD\|377582
NZ_CP047374.1\|WP_005321299.1\|2923401_2925051_-\|glucose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|234679
NZ_CP047374.1\|WP_017411691.1\|2929429_2930104_+\|JAB-domain-containing-protein	unknown	unknown	gnl\|CDD\|178801
NZ_CP047374.1\|WP_005321648.1\|2910388_2910880_-\|RNA-binding-protein	unknown	unknown	gnl\|CDD\|240845
NZ_CP047374.1\|WP_005321658.1\|2906457_2907360_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176120
NZ_CP047374.1\|WP_017412961.1\|2904539_2905049_-\|5-(carboxyamino)imidazole-ribonucleotide-mutase	unknown	unknown	gnl\|CDD\|376377
NZ_CP047374.1\|WP_005321666.1\|2905111_2905414_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047374.1\|WP_005321291.1\|2927475_2927934_-\|dUTP-diphosphatase	unknown	unknown	gnl\|CDD\|234802
NZ_CP047374.1\|WP_005321651.1\|2909578_2910370_+\|glutamate-racemase	unknown	unknown	gnl\|CDD\|234851

Protein	Function_ID	Function_description	E-value
NZ_CP047374.1\|WP_159364243.1\|2903418_2904543_-\|5-(carboxyamino)imidazole-ribonucleotide-synthase	gnl\|CDD\|235674	PRK06019, PRK06019, phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed.	1.12308e-174
NZ_CP047374.1\|WP_159364246.1\|2916794_2919365_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|223972	COG1042, COG1042, Acyl-CoA synthetase (NDP forming) [Energy production and conversion].	5.48813e-163
NZ_CP047374.1\|WP_102665385.1\|2919820_2920693_+\|transporter-substrate-binding-domain-containing-protein	gnl\|CDD\|366132	pfam00497, SBP_bac_3, Bacterial extracellular solute-binding proteins, family 3.	3.20487e-07
NZ_CP047374.1\|WP_005321293.1\|2926810_2927407_-\|nucleoid-occlusion-factor-SlmA	gnl\|CDD\|181894	PRK09480, slmA, division inhibitor protein; Provisional.	5.35e-120
NZ_CP047374.1\|WP_159364247.1\|2921763_2923245_+\|ketol-acid-reductoisomerase	gnl\|CDD\|235368	PRK05225, PRK05225, ketol-acid reductoisomerase; Validated.	0
NZ_CP047374.1\|WP_005321282.1\|2928079_2929282_-\|bifunctional-phosphopantothenoylcysteine-decarboxylase/phosphopantothenate--cysteine-ligase-CoaBC	gnl\|CDD\|235513	PRK05579, PRK05579, bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated.	0
NZ_CP047374.1\|WP_005321271.1\|2930240_2930477_+\|50S-ribosomal-protein-L28	gnl\|CDD\|234736	PRK00359, rpmB, 50S ribosomal protein L28; Reviewed.	3.10301e-34
NZ_CP047374.1\|WP_005307500.1\|2930488_2930656_+\|50S-ribosomal-protein-L33	gnl\|CDD\|179075	PRK00595, rpmG, 50S ribosomal protein L33; Validated.	7.40188e-23
NZ_CP047374.1\|WP_005321295.1\|2925823_2926660_-\|mechanosensitive-ion-channel	gnl\|CDD\|182386	PRK10334, PRK10334, small-conductance mechanosensitive channel MscS.	7.02959e-94
NZ_CP047374.1\|WP_159364244.1\|2905419_2906493_-\|sodium-dependent-bicarbonate-transport-family-permease	gnl\|CDD\|377582	pfam05982, Sbt_1, Na+-dependent bicarbonate transporter superfamily. Family of bacterial proteins that are likely to be part of the Na(+)-dependent bicarbonate transporter (sbt) family. Members carry 10TMS in a 5+5 duplicated structure. The loop between helices 5 and 6 in Synechocystis PCC6803 is likely to be the location for regulatory mechanisms governing the activation of the transporter.	5.9597e-132
NZ_CP047374.1\|WP_005321299.1\|2923401_2925051_-\|glucose-6-phosphate-isomerase	gnl\|CDD\|234679	PRK00179, pgi, glucose-6-phosphate isomerase; Reviewed.	0
NZ_CP047374.1\|WP_017411691.1\|2929429_2930104_+\|JAB-domain-containing-protein	gnl\|CDD\|178801	PRK00024, PRK00024, DNA repair protein RadC.	9.16629e-136
NZ_CP047374.1\|WP_005321648.1\|2910388_2910880_-\|RNA-binding-protein	gnl\|CDD\|240845	cd12399, RRM_HP0827_like, RNA recognition motif in Helicobacter pylori HP0827 protein and similar proteins. This subfamily corresponds to the RRM of H. pylori HP0827, a putative ssDNA-binding protein 12rnp2 precursor, containing one RNA recognition motif (RRM), also termed RBD (RNA binding domain) or RNP (ribonucleoprotein domain). The ssDNA binding may be important in activation of HP0827. .	9.92965e-31
NZ_CP047374.1\|WP_005321658.1\|2906457_2907360_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176120	cd08429, PBP2_NhaR, The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold. NhaR is a positive regulator of the LysR family and is known to be an activator of the nhaA gene encoding a Na(+)/H(+) antiporter. In Escherichia coli, NhaA is the vital antiporter that protects against high sodium stress, and it is essential for growth in high sodium levels, while NhaB becomes essential only if NhaA is not available. The nhaA gene of nhaAR operon is induced by monovalent cations. The nhaR of the operon activates nhaAR, as well as the osmC transcription which is induced at elevated osmolarity. OsmC is transcribed from the two overlapping promoters (osmCp1 and osmP2) and that NhaR is shown to activate only the expression of osmCp1. NhaR also activates the transcription of the pgaABCD operon which is required for production of the biofilm adhesion, poly-beta-1,6-N-acetyl-d-glucosamine (PGA) .Thus, it is suggested that NhaR has an extended role in promoting bacterial survival. This substrate-binding domain has significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.59501e-81
NZ_CP047374.1\|WP_017412961.1\|2904539_2905049_-\|5-(carboxyamino)imidazole-ribonucleotide-mutase	gnl\|CDD\|376377	pfam00731, AIRC, AIR carboxylase. Members of this family catalyze the decarboxylation of 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR). This family catalyze the sixth step of de novo purine biosynthesis. Some members of this family contain two copies of this domain.	9.2067e-81
NZ_CP047374.1\|WP_159364245.1\|2907626_2909462_+\|TonB-dependent-receptor	gnl\|CDD\|236730	PRK10641, btuB, TonB-dependent vitamin B12 receptor BtuB.	1.88367e-176
NZ_CP047374.1\|WP_005321291.1\|2927475_2927934_-\|dUTP-diphosphatase	gnl\|CDD\|234802	PRK00601, dut, dUTP diphosphatase.	5.7864e-97
NZ_CP047374.1\|WP_005321651.1\|2909578_2910370_+\|glutamate-racemase	gnl\|CDD\|234851	PRK00865, PRK00865, glutamate racemase; Provisional.	5.6724e-109

>NZ_CP047374.1|WP_102665385.1|2919820_2920693_+|transporter-substrate-binding-domain-containing-protein
MIRILLWCITLFAGSALAAESHIRAWNLLLEHPNPAVAGLLRLSLDLTVPEYGPYQLIASPPMEQGRAVKALQEGALVQIGVFAPDEERERSLLAVHIPLAKGLLGWRVCLIRLGDEGRFSGIGSLADWHSAGLTIGQHRSWPDTRLLKANGLKVTVGNLYEALFNMLSKRRFDCFLRSVIEIEDELKQHPELAIEPHLVFRYPLALLFFVSPQYPELAQRIELGLQRARQSGAFDQIFEKEFGSTIRRLKLDERVMLELHNPDLPARSRIMMADPSLIYAPVTATPSAQ
>NZ_CP047374.1|WP_159364246.1|2916794_2919365_-|GNAT-family-N-acetyltransferase
MKPSGLDRLFKPHSIAVIGASTDPQKAGHVVIRHLLAGQFKGPILPVSPHNKAIAGVLAYPDIASLPLSPDLAIICTKRERVLSLIEALGKKGAGAAIILAADFSQEEREQLQRLSSQYDIRLLGPNSMGMLLPAQGINASFSPIAAKPGQVAFVSQSAAVSTTILDWAKQHELGFSAFISLGDHCDIDFGQLLDQLSRDGTTRAILLYMDKLHDARHFLSAARAASRNKPILVLKSGRHDPAKGLDNVYDAAIRRAGMLRVRDTHELFAAVETLSHSLTLKGERLAIISNGRGLANMAVDVLLERGGKLAIPPKDIGSDADITAYQQALDALLQGNEADAILLIHAPSLTARGAELARSLIDYLRQHPRARHFNILTNWAGEYSAQEGRKLFTEAGIPTYRTPESAVAAFMHMVEYRRNQKQLMETPASLQGDKLNVELCQQLIRQALERKQLTLDTHLVQPILQAAGLATLPTWIVSDAIEATLTAEQIGYPVAVKLRSPDIAHKSAVHGVMLNLRTSAEVAQAADAILDRVRQHDAGARIEGLLVQRMARRSGGLELRIRLQQDPVFGPVILLGESGAEPQEMVAALPPLNQALARYQVIGALKSRKIREQATPERLDIDALGQVLCQLSELLLAFPEIQELDLHPLQACGAEMVILDASLTLMPMTQQRCPLAIRPYPTELEEGAWLKDQSHVLLRPIRPEDEPAHKQFVLKVSDEDRYKRFFADVGELGHEELARMTQIDYDREMAFVAVGQDGAFSQQILGVVRAISNPDQSDAEFAILVRSDLKGLGLGKLMMEKIVRYARERGIGQLSGMTMPSNRGMINLAKRLGFKIDIQLEDGVVNMELPCAERA
>NZ_CP047374.1|WP_005321648.1|2910388_2910880_-|RNA-binding-protein
MNLSKFPVYVQAAILALVLALVGYLVAQALQFSLKAEVIFAVGLAIGGFIVPLFLKRTPAAAGELASGQETCTLYVGNLPYRANEIAVRELFAEQGQVISVRLMKDKATGKRRGFGFVEMPAADAAKAIAVLNDKEYQQRTLKVREANDKRDKDEREGSEVDA
>NZ_CP047374.1|WP_005321651.1|2909578_2910370_+|glutamate-racemase
MANILVFDSGMGGLTIYREIRRALPAHNYFYCFDNANFPYGELSESALIAACTRLVSHMVAEHVIDLVVIACNTASTIALPSLRAALTIPVVGVVPAIKPAAALTRNGCIGLLATPGTVSREYTHHLIAQFAPGKRVLLKGATELVIEAEHKLAGRPVNMALLQEVLTDWMEGEERPDTLVLGCTHFPLLNDEIRQLMPGCQLVDSGSAVARRVAHLLATVAEQPSQAVVQARAYCTRLDAQAQKLTAPLQAWGLSSLEEVQY
>NZ_CP047374.1|WP_159364245.1|2907626_2909462_+|TonB-dependent-receptor
MSKTLLVAALLPTAAFAQTTIAVNPTLVITANRVEQPISSVLAPVVVIDRAEIESRQVQSLPALLKTLPGVQITTLGGRGHMSSLFIRGTNSNHSLVLMNGRPIAAMVAGTPDLSQIPLGNIERIEYIRGPRAAVYGADAIGGVINLITKTSAKNGSETHLKGGVGSNGYGQGQVRTVQALGQQTDMNMMIGYERTDGFDVVANAQQPDRDGFDSLNGQFGLNHGFSDAWSGDFNAQGYDNQTEMDDAYQSADQSRVQAFQYDGGLKFQSETLTSRLEASYGENKLKSWLESKGESSAQPIHTGLTRFSWINSWSGVEGLNLTGGADWQQEQLKSDSRSSGLAFNAPDRDNTGLFAVGSYRWQALLWELSGRTDDNEQYGRHNTWSAASGLDIDDNHNVRLSYGTGFKAPTFLDLYYPGYENPDLKPEESKNLELGFAGRYTGWDWSLNLYRNKIQNLIACQSAFSTCKPDNTDAEIRGVEVALGLETGPIHHDLSFDYTRAEDKNDGDQQLLRRAKQKASWLTQVQLGPVDLSTELLYVGKWDDKNFSSFPAERVELGSYTLINLGASYGVTPQLTLGGRIDNLFDRDYAPAYGYASAGTEFKLTADYRL
>NZ_CP047374.1|WP_005321658.1|2906457_2907360_+|LysR-family-transcriptional-regulator
MLNYKQLYYFWHVARSGSVTRAAEQLHLTPQTISGQVAELELSLGVALFSREGRRLVLTAAGRQALEQAGAIFSLGAELEHTLRHASQELTMQVGIADSVPRTLAFELLAPAMALATPVRLICHEERAEQLFSELARHKLDMVLIDRPLPPDSGVRGYNHELGRSPLALFASPALAARARSGFPASLEGLPLLIPGEKSATHDRLLAWYRQQGIHPHLVGQFDDSTLMKSFGKAGMGIFPAPLAMRDEIERLYGVERIATLPEVTLSYYLVSAGRHLSHPGVQAVMEGARQRLVELEKQK
>NZ_CP047374.1|WP_159364244.1|2905419_2906493_-|sodium-dependent-bicarbonate-transport-family-permease
MPEVIELFVVEHSGSYQFLPNNHQSKSDFIEASCTLACKHPVNCLLRPLMLDIVVLFFLFGLLAGLVRSELKLPPALYDTLSLFLLLAIGLKGGVGLAQQSLLPLLPQLALVILLGVVQTLAGFALLRIKMNRIDAAATAAHYGSVSVATFAVGVNWLTERGISFESQLSIFLAVMEIPAILVGIMLARGVSRQTRWRMLAHETFLGKGVTLLLGGMAIGYLAGPQGIAPLKPLFVDLFKGALALFLLEMGLIVARQCQDLRRHGLFLLGFALLMPLASAGLGLTVGKLMGLSLGGLTLLATLAASASYIAVPATLRIAVPQANPGLSLSAVLGVTFPFNIMLGIPLYHSWARHFTE
>NZ_CP047374.1|WP_005321666.1|2905111_2905414_-|hypothetical-protein
MQTETRTLLTVITEANLEPTLLRTLTREGLRGYTITDARGRGDHGERNASWSESGNIRLEAICSREQAERLLAHLQSRYYPDYAMIAFLQPVEIVRPEKF
>NZ_CP047374.1|WP_017412961.1|2904539_2905049_-|5-(carboxyamino)imidazole-ribonucleotide-mutase
MNTPPLIGLVMGSDSDWPVLQAAARILKEHGVPYEARVVSAHRTPDLLFEYAASARDRGLRAIIAGAGGAAHLPGMVAAKTTVPVLGVPIPSRHLKGMDSLLSIVQMPKGVPVATFAIGEAGAANAALFAVSLLSVTLDGDAPRYQQQLDDFRANERDRVLALQLEDPA
>NZ_CP047374.1|WP_159364243.1|2903418_2904543_-|5-(carboxyamino)imidazole-ribonucleotide-synthase
MILPPATLGMLGGGQLGRYFVMAAHRLGYKMVVLDPDPASIAGAAADHHIVAPYDDQTALHDLASRCAAISCEFENVPAATLALLEKQKPMRPAASAVRICQDRREEKAFLRGADIPVAPHLALLAGDPIPAQASALFPAILKTAREGYDGKGQWQVGNLDELASALTASGVPCVLEKRLPLEGEFALTLARSPSGAISALPLVQNWHSGGILDQTRSPANVPALEAEAKDIAERLIAVLDYVGVLTVEFFLVEGRLLVNEMAPRPHNSGHPSLDNAECSQFELQVRALCDLPLPEKAEVRPAILLNLLGDLWHGGTPDWEGVLALPGVHLHLYGKGEARPGRKMGHVTITGRDWPTLEDTSRHVRSLLGLPPP
>NZ_CP047374.1|WP_159364247.1|2921763_2923245_+|ketol-acid-reductoisomerase
MANYFNTLNLRQQLAQLGKCRFMQRAEFADGCDVLKGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKAAITEKRASWQKAIDNGFAVGTYEELIPTADLVLNLTPDKQHSDVVKTVMPLMKQGAALGYSHGFNVVEEGQQIRADITVVMVAPKCPGTEVREEYKRGFGVPTLLAVHPENDPKGVGMAIAKAWASATGGDRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCYDKLVAEGTDPAYAGKLIQFGWETITEALKQGGISLMMDRLSNPAKLRAFELSEQLRTLMRPLFEKHMDDIIAGEFSRGMMADWAEDDAKLFGWREETGKSAFENAPAFAGKIAEQEYFDNGVVMVAMVKAGVELAFETMVASGIYEESAYYESLHELPLIANTVARKRLYEMNVVISNTAEYGNYLFANAAVPLLREHFMPTLKAGDLGASKAEGQNVDNLALLAANEATRNHPIEKIGQVLRGYMKDMKRIAVGG
>NZ_CP047374.1|WP_005321299.1|2923401_2925051_-|glucose-6-phosphate-isomerase
MKNINPTQTQAWQALEAHFAANKETRLKDLFAQDPKRFDKFSLTFGGDILVDYSKNLITEETLKLLVDLAKETDLRSAIDAMFNGEKINMTEGRSVLHVALRNRSDRPIECDGKDVMPEVNAVLAKMKGFCEKIISGEWKGYTGKAIQHVVNIGIGGSDLGPVMITEALRPYKNHLQMHFVSNVDGTHIAETLKEIDAETTLFLVASKTFTTQETMTNALTARDWFIKIAGDKAHVAKHFAALSTNGKAVAEFGIDTDNMFEFWDWVGGRYSSWSAIGMPIALSVGFDNFEALLQGAFEMDMHFATASYEQNVPVLLALIGLWYNNFHGAESEAILPYDQYMHRFPAYFQQGNMESNGKYVDRNGNPVDHQTGPIIWGEPGTNGQHAFYQLIHQGTKLIPCDFLAPAISHNPIGDHHPKLLANFFAQTEALAFGKSKEQVEAEFLAAGKTLEQVEDLVPFKVFEGNRPTNSILFKSLTPKTLGALIAMYEHKIFVQGAIWNIFSFDQWGVELGKQLANKILPELNTAEAVTSHDCSTNGLINTWKAWKA
>NZ_CP047374.1|WP_005321297.1|2925473_2925662_+|hypothetical-protein
MKHVLSLFALSLIATGLIGLLTLALTAAAPTLEIRVLAVIGAVLGGYALVQPLLNRVARRLL
>NZ_CP047374.1|WP_005321295.1|2925823_2926660_-|mechanosensitive-ion-channel
MEPEIITEAQTWLVNNQGLLIEYAVNIAAALITLLVGYITANLLSNGVIKVMNARKLDATVTHFVGSILKYTILVFVVIAAMGRVGVQTASFVAIIGAAGLAIGLALQGSLSNFAAGFLLIIFRPIKAGEFIEVAGTNGVVQSVQLFTTTLTSGDNKMVVVPNSAILNGTIVNYSRMDTRRVDMTFGIGYGSDLRKAKQLLERLVSEEPRILKEQAATIAVAALADSSVNIVVRPWVKTADYWGVWFDFHEKVKLTFDAEGIEIPFPQMVMHMQKPQA
>NZ_CP047374.1|WP_005321293.1|2926810_2927407_-|nucleoid-occlusion-factor-SlmA
MASSNQKQSRRDQILQALAHMLETSPGQRITTARLAAEVGVSEAALYRHFPSKARMFEGLIDFIEDSLLSRVNLIMAEEKDTMARCHHILQLLLVFAERNPGITRILNGDALLGEHDRLRDRISILFDKLETQIKQVLREKRLREGQGFQLDETMLANLLLAYTEGRISQFVRSEFKLKPTAGFEDQWLFIRSQLLQS
>NZ_CP047374.1|WP_005321291.1|2927475_2927934_-|dUTP-diphosphatase
MTTQIELKILDARIGTEYPLPAYATPGSAGMDLRALLDAPITLAPGDTILVPTGLAIHIQDPGLCATILPRSGLGHKHGIVLGNLVGLIDSDYQGQLMVSVWNRGNDSFTMQPGERIAQLVIMPVVQASFQLVDEFNQSERGEGGFGSSGRQ
>NZ_CP047374.1|WP_005321282.1|2928079_2929282_-|bifunctional-phosphopantothenoylcysteine-decarboxylase/phosphopantothenate--cysteine-ligase-CoaBC
MRLADKRILLGVSGGIAAYKSAELVRRLKDQGAEVRVVMTRSAKEFITPLTLQAVSGHPVADSLLDPAAEAGMGHIELAKWADLVLIAPASANLMARMAAGMADELLTTLCVATPAPVALAPAMNQQMYLNAATQANLKTLASRGILLWGPDSGSQACGDVGPGRMLDPLELVERCCQQLAAEPLLAGVRLLLTAGPTREALDPVRYISNHSSGKMGYAIARAAREAGAEVTLVSGPVALPAPSGVERVDVESAEQMHQAVMSRVGECDLFIGCAAVADYRPEQVASQKIKKTGDNDQMVLTLVKNPDIIAAVGALSDKPFTVGFAAETVDVEQYALDKLQRKRLDMIAANDVSRAGQGFNADDNALTVFWQGGQAPLPLADKLTLARHLIALIARHYRR
>NZ_CP047374.1|WP_017411691.1|2929429_2930104_+|JAB-domain-containing-protein
MSIKEWPEDERPREKLLRQGPATLSDAELLAIFLRTGVNGLSAVDLSRQLLQQFGSLRALLGADQGAFCHAHGLGPAKYAQLQAVLEMGKRHLAEQLQRGDALTSPQLTRDYLQAQLRDRPREVFALLLLDNQHRVIQFVELFYGTLDSASVWPREIVQIALKHNAAAVILAHNHPSGVAEPSRADRQITDRILAALALIDIRVLDHLVIGDGITVSFAERGWL
>NZ_CP047374.1|WP_005321271.1|2930240_2930477_+|50S-ribosomal-protein-L28
MSRVCQVTGKRPAVGNNRSHANNATKRRFLPNLHTHRFWVEGEKRFVSLRVSAKGMRIIDKRGVEVVLAELRASGVKV
>NZ_CP047374.1|WP_005307500.1|2930488_2930656_+|50S-ribosomal-protein-L33
MAKGIREKIRLNSSAGTGHFYTTTKNKRTMPEKMEIKKFDPVVRQHVIYKEGKIK

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Crispr_ID: NZ_CP047374_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047374_8

4422252-4422375

Orphan

Consensus_repeat	Method
TGTTGCCGCGGACGATTACGCTTCGCTAATCGACCCTACA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP047374_8

>merge|NZ_CP047374|8|4422252-4422375|CRISPRCasFinder
TGTTGCCGCGGACGATTACGCTTCGCTAATCGACCCTACACGCTTATTGGCACCCTACCTGTCTCCCGCAAGGGGAGAGGGGATTGTTGCCGCGGACGATTACGCTCCGCTAATCGACCCTACA

>NZ_CP047374|8|8|4422252-4422375|CRISPRCasFinder
TGTTGCCGCGGACGATTACGCTTCGCTAATCGACCCTACA	CGCTTATTGGCACCCTACCTGTCTCCCGCAAGGGGAGAGGGGAT
TGTTGCCGCGGACGATTACGCTCCGCTAATCGACCCTACA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047374.1\|WP_076611341.1\|4421013_4421931_+\|IS5-like-element-ISAs4-family-transposase	unknown	unknown	gnl\|CDD\|290455
NZ_CP047374.1\|WP_005319166.1\|4414484_4415891_-\|hexose-6-phosphate:phosphate-antiporter	unknown	unknown	gnl\|CDD\|236564
NZ_CP047374.1\|WP_017412979.1\|4425587_4426334_-\|transporter-substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|270422
NZ_CP047374.1\|WP_005319168.1\|4413965_4414271_-\|PTS-sugar-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|224362
NZ_CP047374.1\|WP_005314579.1\|4429143_4429701_-\|TMEM165/GDT1-family-protein	unknown	unknown	gnl\|CDD\|225030
NZ_CP047374.1\|WP_085941442.1\|4429945_4430320_-\|stress-response-translation-initiation-inhibitor-YciH	unknown	unknown	gnl\|CDD\|181613
NZ_CP047374.1\|WP_034282846.1\|4424725_4425472_-\|transporter-substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|270422
NZ_CP047374.1\|WP_042468762.1\|4409442_4410054_-\|high-frequency-lysogenization-protein-HflD	unknown	unknown	gnl\|CDD\|234690
NZ_CP047374.1\|WP_088814280.1\|4412152_4413127_-\|pseudouridine-synthase	unknown	unknown	gnl\|CDD\|211334
NZ_CP047374.1\|WP_005319178.1\|4410251_4411358_-\|tRNA-2-thiouridine(34)-synthase-MnmA	unknown	unknown	gnl\|CDD\|234664
NZ_CP047374.1\|WP_011898521.1\|4418873_4419626_+\|phosphotransferase	unknown	unknown	unknown
NZ_CP047374.1\|WP_005319170.1\|4413197_4413965_-\|PTS-transporter-subunit-EIIA	unknown	unknown	gnl\|CDD\|334031
NZ_CP047374.1\|WP_005314572.1\|4422493_4422802_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047374.1\|WP_159364507.1\|4430618_4432889_+\|Fe(2+)-transporter-permease-subunit-FeoB	unknown	unknown	gnl\|CDD\|236563
NZ_CP047374.1\|WP_005314577.1\|4426907_4427915_-\|DUF4401-domain-containing-protein	unknown	unknown	gnl\|CDD\|379574
NZ_CP047374.1\|WP_011898520.1\|4411676_4412138_-\|NUDIX-hydrolase	unknown	unknown	gnl\|CDD\|239647
NZ_CP047374.1\|WP_017412111.1\|4432885_4433128_+\|LuxR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|370243
NZ_CP047374.1\|WP_005314583.1\|4430394_4430622_+\|ferrous-iron-transport-protein-A	unknown	unknown	gnl\|CDD\|377199
NZ_CP047374.1\|WP_005314576.1\|4426407_4426911_-\|GDYXXLXY-domain-containing-protein	unknown	unknown	gnl\|CDD\|379571
NZ_CP047374.1\|WP_159364506.1\|4417500_4418418_-\|IS5-like-element-ISAs4-family-transposase	unknown	unknown	gnl\|CDD\|290455

Protein	Function_ID	Function_description	E-value
NZ_CP047374.1\|WP_076611341.1\|4421013_4421931_+\|IS5-like-element-ISAs4-family-transposase	gnl\|CDD\|290455	pfam13737, DDE_Tnp_1_5, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.	2.87975e-48
NZ_CP047374.1\|WP_005319166.1\|4414484_4415891_-\|hexose-6-phosphate:phosphate-antiporter	gnl\|CDD\|236564	PRK09556, uhpT, hexose-6-phosphate:phosphate antiporter.	0
NZ_CP047374.1\|WP_017412979.1\|4425587_4426334_-\|transporter-substrate-binding-domain-containing-protein	gnl\|CDD\|270422	cd13704, PBP2_HisK, The periplasmic sensor domain of histidine kinase receptors; the type 2 periplasmic binding fold protein. This subfamily includes the periplasmic sensor domain of the histidine kinase receptors (HisK) which are elements of the two-component signal transduction systems commonly found in bacteria and lower eukaryotes. Typically, the two-component system consists of a membrane-spanning histidine kinase sensor and a cytoplasmic response regulator. The two-component systems serve as a stimulus-response coupling mechanism to enable microorganisms to sense and respond to changes in environmental conditions. Extracellular stimuli such as small molecule ligands and ions are detected by the N-terminal periplasmic sensing domain of the sensor kinase receptor, which regulate the catalytic activity of the cytoplasmic kinase domain and promote ATP-dependent autophosphorylation of a conserved histidine residue. The phosphate is then transferred to a conserved aspartate in the response regulator through a phospho-transfer mechanism, and the activity of the response regulator is in turn regulated. The sensor domain belongs to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space through their function as an initial high-affinity binding component. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.11776e-28
NZ_CP047374.1\|WP_005319168.1\|4413965_4414271_-\|PTS-sugar-transporter-subunit-IIB	gnl\|CDD\|224362	COG1445, FrwB, Phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism].	4.38784e-41
NZ_CP047374.1\|WP_005314579.1\|4429143_4429701_-\|TMEM165/GDT1-family-protein	gnl\|CDD\|225030	COG2119, COG2119, Predicted membrane protein [Function unknown].	2.56269e-51
NZ_CP047374.1\|WP_085941442.1\|4429945_4430320_-\|stress-response-translation-initiation-inhibitor-YciH	gnl\|CDD\|181613	PRK09019, PRK09019, stress response translation initiation inhibitor YciH.	4.42658e-37
NZ_CP047374.1\|WP_034282846.1\|4424725_4425472_-\|transporter-substrate-binding-domain-containing-protein	gnl\|CDD\|270422	cd13704, PBP2_HisK, The periplasmic sensor domain of histidine kinase receptors; the type 2 periplasmic binding fold protein. This subfamily includes the periplasmic sensor domain of the histidine kinase receptors (HisK) which are elements of the two-component signal transduction systems commonly found in bacteria and lower eukaryotes. Typically, the two-component system consists of a membrane-spanning histidine kinase sensor and a cytoplasmic response regulator. The two-component systems serve as a stimulus-response coupling mechanism to enable microorganisms to sense and respond to changes in environmental conditions. Extracellular stimuli such as small molecule ligands and ions are detected by the N-terminal periplasmic sensing domain of the sensor kinase receptor, which regulate the catalytic activity of the cytoplasmic kinase domain and promote ATP-dependent autophosphorylation of a conserved histidine residue. The phosphate is then transferred to a conserved aspartate in the response regulator through a phospho-transfer mechanism, and the activity of the response regulator is in turn regulated. The sensor domain belongs to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space through their function as an initial high-affinity binding component. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.18127e-25
NZ_CP047374.1\|WP_042468762.1\|4409442_4410054_-\|high-frequency-lysogenization-protein-HflD	gnl\|CDD\|234690	PRK00218, PRK00218, lysogenization regulator HflD.	5.50598e-112
NZ_CP047374.1\|WP_088814280.1\|4412152_4413127_-\|pseudouridine-synthase	gnl\|CDD\|211334	cd02566, PseudoU_synth_RluE, Pseudouridine synthase, Escherichia coli RluE. This group is comprised of bacterial proteins similar to E. coli RluE. Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi). No cofactors are required. Escherichia coli RluE makes psi2457 in 23S RNA. psi2457 is not universally conserved.	7.00506e-88
NZ_CP047374.1\|WP_005319178.1\|4410251_4411358_-\|tRNA-2-thiouridine(34)-synthase-MnmA	gnl\|CDD\|234664	PRK00143, mnmA, tRNA-specific 2-thiouridylase MnmA; Reviewed.	0
NZ_CP047374.1\|WP_159364507.1\|4430618_4432889_+\|Fe(2+)-transporter-permease-subunit-FeoB	gnl\|CDD\|236563	PRK09554, feoB, Fe(2+) transporter permease subunit FeoB.	0
NZ_CP047374.1\|WP_005319170.1\|4413197_4413965_-\|PTS-transporter-subunit-EIIA	gnl\|CDD\|334031	pfam00359, PTS_EIIA_2, Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2.	1.01246e-19
NZ_CP047374.1\|WP_005314577.1\|4426907_4427915_-\|DUF4401-domain-containing-protein	gnl\|CDD\|379574	pfam14351, DUF4401, Domain of unknown function (DUF4401). This family of proteins is found in bacteria. Proteins in this family are typically between 357 and 735 amino acids in length. The family is found in association with pfam09925. There is a single completely conserved residue K that may be functionally important.	2.25952e-33
NZ_CP047374.1\|WP_011898520.1\|4411676_4412138_-\|NUDIX-hydrolase	gnl\|CDD\|239647	cd03675, Nudix_Hydrolase_2, Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity. They also contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which forms a structural motif that functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	2.96013e-66
NZ_CP047374.1\|WP_017412111.1\|4432885_4433128_+\|LuxR-family-transcriptional-regulator	gnl\|CDD\|370243	pfam09012, FeoC, FeoC like transcriptional regulator. This family contains several transcriptional regulators, including FeoC, which contain a HTH motif. FeoC acts as a [Fe-S] dependant transcriptional repressor.	3.80685e-22
NZ_CP047374.1\|WP_005314583.1\|4430394_4430622_+\|ferrous-iron-transport-protein-A	gnl\|CDD\|377199	pfam04023, FeoA, FeoA domain. This family includes FeoA a small protein, probably involved in Fe2+ transport. This presumed short domain is also found at the C-terminus of a variety of metal dependent transcriptional regulators. This suggests that this domain may be metal-binding. In most cases this is likely to be either iron or manganese.	2.19469e-16
NZ_CP047374.1\|WP_005314576.1\|4426407_4426911_-\|GDYXXLXY-domain-containing-protein	gnl\|CDD\|379571	pfam14345, GDYXXLXY, GDYXXLXY protein. This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 171 and 199 amino acids in length. It contains a conserved GDYXXLXY motif.	4.47387e-37
NZ_CP047374.1\|WP_159364506.1\|4417500_4418418_-\|IS5-like-element-ISAs4-family-transposase	gnl\|CDD\|290455	pfam13737, DDE_Tnp_1_5, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.	2.18364e-47

>NZ_CP047374.1|WP_076611341.1|4421013_4421931_+|IS5-like-element-ISAs4-family-transposase
MGKALHPITNWPQYNRSLINRGSLTFWVDAEAMDNWFHQDHHGKRGRSQLYTDQSICTFLMLKGIFSLTLRATQGLLDSLFELMNVPLCAPDYSCVSKRARTVKVAYRQPPKGRITDLVIDSTGLKVFGEGEWKVRKHGAEKRRVWRKLHLAVDPVTHDIVAAEVSLENVHDAEVLPTLLNPLRRKLGRVYADGAYDSKASHRLIARKGATACIPPRKNAGLWKKGHPRNEAVQVMRKEGLAHWKKISGYHRRSLAETAMFRFKQLMAGQITLRKYNGQVGEVMAYVSAINKLNTLGLPVRKPRV
>NZ_CP047374.1|WP_011898521.1|4418873_4419626_+|phosphotransferase
MGGASVNIQLLDGKPCIRKSGASSVERHFYQRAAPHLRGVNTPALLRVEGETLFLEQIPNPVPLTQLHHNEQTFVQLASLHNSRYQPDFALKAHDWSLADTSEALSVLCLPESASETIRHIQQLGRELFAEPCLISGDSNEGNWGTRDNGELVLFDWERFGYGSPTIDLAPLVPQMGSLAEYEAIIEHYLRHSSLLSGERLLRHLIMAKCWLIIEVTNLLTRREKPQAQRYLDWYRQQVPHWLDSVAHMI
>NZ_CP047374.1|WP_159364506.1|4417500_4418418_-|IS5-like-element-ISAs4-family-transposase
MGKALHPITNWPQYNRSLINRGSLTFWVDAEAMDNWFHQDHHGKRGRSQLYTDQSICTFLMLKGIFSLTLRATQGLLDSLFELMNVPLCAPDYSCVSKRACTVKVAYRQPPKGRITDLVIDSTGLKVFGEGEWKVRKHGAEKRRVWRKLHLAVDPVTHDIVAAEVSLENVHDAEVLPTLLNPLRRKLGRVYADGAYDSKASHRLIARKGATACIPPRKNAGLWKKGHPRNEAVQVMRKEGLAHWKKISGYHRRSLAETAMFRFKQLMAGQITLRKYNGQVGEVMAYVSAINKLNTLGLPVRKPRV
>NZ_CP047374.1|WP_005319166.1|4414484_4415891_-|hexose-6-phosphate:phosphate-antiporter
MLKFLQQVRVPTLELPVEARRKLWFKPFMQSYLVVFIGYLTMYLIRKNFNIAQNDMIQEYGLSMTELGMIGLGFSITYGVGKTVVSYYADGKNTKQFLPLMLILSALCMLGFSASMGGTGFSLYFMIFFYALSGFFQSCGGSCSYSTITKWTPRNKRGTYLGMWNLSHNVGGAGAAGVALFGANYLFDGNVLGMFIFPSMIALVVGFIGLRFGSDSPEAYGLGKVEELFDEVASEEDIATEEQKLTKGQIFVKYVLMNKVIWLLCFANIFLYVVRIGIDQWSTVYAHQELGFSKEIAIQGFTFFEVGALVGTLMWGYLSDLANGRRGLVACVALALIIATLGLYQHATTQFMFLGSLFLLGFLVFGPQLLIGVAAVGFVPKQGISVADGVKGTFAYLIGDSFAKLGLGMIADGTPIFGLTGWAGTFAALDMAAAACLVLMACVAVAEERKIRRIKRELKAATLATQSA
>NZ_CP047374.1|WP_005319168.1|4413965_4414271_-|PTS-sugar-transporter-subunit-IIB
MKILAVTACPTGIAHTYMAAEALQKAADKLGLKIKVETQGAMGLENILTARDIASADLVLIASDIEIEQKDRFLGCTVRQVSLESVLLNASAVLKTATVGV
>NZ_CP047374.1|WP_005319170.1|4413197_4413965_-|PTS-transporter-subunit-EIIA
MLTRELTFFCRLGLTITQAKQLSRLAGLFKSHIQLINVTRRQRVVATSQLSLLTLATQPGDLCLLLIEGLDAELAHMAFTCWCVELGQPLGRPGSAAPAEQRLGLAQPDYCFSLAQLGHAAASLDKSLALRVLIDLLPAELVRDRPALEQAIAKREQIAATIIRPGLAMPHVICPAIRQPALSLLSCAEPIEWGSALGPVRTIILLAIPAGLAPEQLRPLTRLARAMMDEVVSTALLHASSAPARQAIVIEGLLS
>NZ_CP047374.1|WP_088814280.1|4412152_4413127_-|pseudouridine-synthase
MHAMKSARPRLSLQGRTTAAGRTPQDDANQPGLTRSRAGTRHAQAAEQAGQKPQVAPADRKLLLLNKPYMVLCQFTDEAGRETLKDYIKEPGIYAAGRLDRDSEGLLLLTNDGKLQARLTQPGEKTPKTYWVQVEGIPSEEELAALRAGVELNDGLTLPAEARLMDEPNVWPRNPPIRERKEIPTRWLEIKIVEGRNRQVRRMTAHIGHPTLRLIRYAIGDWTLGNWQEDGLAPGESRSLPAPELAPVSPARPRKPQTGSSTAKPANDRPRRTAQSNRKNPPRSAGKPAIDQAGSRPPAESKPRSSGRGTARRPARHTTDKESS
>NZ_CP047374.1|WP_011898520.1|4411676_4412138_-|NUDIX-hydrolase
MEERMPARLTVAALVHWQGRFLLVEEEIKGQRRFNQPAGHVEPGENLIEAACRELKEETGLTATPSAWLGVYLYKPADSEATFVRTAVIFDLEKAPGQHHPEDPDGDVLACHWLTLEEIAECKPALRSPLVWQCIQDYLGGTRLPLSALKAFI
>NZ_CP047374.1|WP_005319178.1|4410251_4411358_-|tRNA-2-thiouridine(34)-synthase-MnmA
MTDNSQIKVIVGMSGGVDSSVSAYLLQQQGYQVEGLFMKNWEEDDTDEYCSASQDLADAKAVCDKLGMKLHTINFAAEYWDNVFEHFLEEYKAGRTPNPDILCNKEIKFKAFLEFAAEELGATYIATGHYVRRDDSTGHPRLLRGLDSNKDQSYFLYTLSEKQVGQSLFPVGDLEKPEVRRIAEQLDLITAKKKDSTGICFIGERKFKDFLAKFLPAQPGPIETVDGKVIGEHQGLMYHTLGQRKGLGIGGRKDATEEAWYVVDKEVERNTLVVAQGEHPRLYSDGLIASQLHWVDRTPIRAPRRCTVKTRYRQQDIPCLIQPIDDETIRVIFDEKQAAVTPGQSAVFYDGEVCLGGGIIEQRFSHPV
>NZ_CP047374.1|WP_042468762.1|4409442_4410054_-|high-frequency-lysogenization-protein-HflD
MSDKFQDRTMAFAGICQAAYLVQKVARDGTCDEASLHESLQSVLVTDPKQPLEVFGNHLAIRDGYRALVEQLGSDGSQKNAELTRYVVSLIALERKLAKRKDILNMLGERISQIGRQQQHFDLLDEQILANMASIYSDLISPIGPRIQIAGTPLFLQQPLVQHKVRALLLAGIRACVLWRQLGGSRTQIIFARKKMVELAKRF
>NZ_CP047374.1|WP_005314572.1|4422493_4422802_+|hypothetical-protein
MANRFVSSKNRIVQAGRWLATRGAALFAELSEFQQRIWVVSIVNDTYTDTFIVNEGSFEEPMQWMRRKQYDADMLQRVEAMQRSQVIQFELGDTRHRLMRVK
>NZ_CP047374.1|WP_034282846.1|4424725_4425472_-|transporter-substrate-binding-domain-containing-protein
MKKWIGFAALLFAAITQASQELGKLHYLSEEYKPYNYTDSAGTPTGLAVELLHQVWKKTNTPPQTITIMPWARGYYLLTQKPNVVLFATARTEARDPLFKWACPIGYAEIVLIGLAKNPLTLTKLEDAQQHTIGAVRADVGEQLLLNNGFDEQKIMAANRLPQALKMLTSGRVDLISTNKTTLMDLIASQQLDPAQFKVFWMLSSEQFCFAFSHPVSDELVKEFQNGLTQVLASSEFQQIQHKYFPVP
>NZ_CP047374.1|WP_017412979.1|4425587_4426334_-|transporter-substrate-binding-domain-containing-protein
MRIRLCCCLLLMSCLGTAHAGLTKLEYLTEEYPPYNFSNEAGQPTGLAVDLLQLIWQRSGTAAQPVRILPWARGYYLLTQKPNVVLFSTARTETRSHLFKWACPIGYSEYILLAHKSKPIQLGAVEQMNDYRISAVRADAAEQLLLNRGMDETRIIPANRLSQALRMLVSGRADLLATSKLAGYDAIKALQLNADDFTVAFVLDAEELCYAFSRQVDDDLVKQFQRAMTQALASPEYQALRQRYLPVP
>NZ_CP047374.1|WP_005314576.1|4426407_4426911_-|GDYXXLXY-domain-containing-protein
MRQLALLLTGLAILAGINFTVWRYEAAMTSGEVVLLRLAPVDPRSLMQGDYMRLNYDIARQLGASRYSERTNDSDTLVIRLDEHQVANWAADGKPEQLASNERLLQVRQSDNQWLIGPDAFFFEEGTGEQFEVARYGEFRLQGDGKALLVGLRDEQFKPVGNPRARW
>NZ_CP047374.1|WP_005314577.1|4426907_4427915_-|DUF4401-domain-containing-protein
MADLTPWQRLQQADLVEGEAPRDTQPHWSSRFLLGMVGWVAALFLLFFLFMSFSQLTQDANSALMMGAVLMAIAFGLNRFAQRSDLWDQFVLALALAADAWLLYGLIDQIDLHSAPLWLGLAALSLFIAALFEHWLIRLFHSFAAAILLTLGLACLGLQLLALPLVMMTLTFCWLQAERQPAYHQLYESLTLGLALSLLVLGRLHHPLWSEGASMLDELGLSRLPLWLNPLLCAALLLGVMIRLKLPLLYGLPLVLISAFIPGMGAGALVLVLGFYAGSMGLMTLAGLLLLGFGSLYYYDLGLTLMTKSWLLLGSGALLLGARQLLHVINARRQS
>NZ_CP047374.1|WP_005314579.1|4429143_4429701_-|TMEM165/GDT1-family-protein
MEALLTSTLSVAIAEIGDKTQLLALLLICRFRKPWPIIAGMLAATLLNHAGAAWLGEFISRWLDPKVMTYLVAGSFIAMAAWILVPDKLDDEESPLDKYGPFMATFVLFFIAEIGDKTQIATVLLAAKYDSLTQVIAGTTLGMMLANVPVVLLGKLGADKLPLKGIRIACAILFAGLGVSTLIFA
>NZ_CP047374.1|WP_085941442.1|4429945_4430320_-|stress-response-translation-initiation-inhibitor-YciH
MSKIKLRLANSQITAMSHDNNSHLVYSTDGGMIKEQTQPQSASPFPQDGTVRIRRETKGRKGAGVITIHGVPAEQQKTIATLLKKKCGTGGGLKEGIIEIQGDKRDLIKTELEKAGFSVKLVGG
>NZ_CP047374.1|WP_005314583.1|4430394_4430622_+|ferrous-iron-transport-protein-A
MVLAQLSPGQSARIKHMNHLERTLRRKLMVMGLLPQTEVLFLRAAPLGDPLQIQCQGICLSMQKSLALQIEVELV
>NZ_CP047374.1|WP_159364507.1|4430618_4432889_+|Fe(2+)-transporter-permease-subunit-FeoB
MNYSLVTVGNPNSGKTSLFNALTGARQQVGNWSGVTVDKKMGEFSAQGHDYKLMDLPGIYSLANQERSLDEQIASRFVQGQQPDLLLNVIDAANLERSLYLTLQLRELGLPMVVVLNKMDILQKRRVTIDEALLAKALGCPVVPLSAHNRQQVAAFKHQIQQFIGKPQPALMLDYGSTLEKDLAELETLLAPHHLTARGRALRLLEEDEAMQETLQAGQQAAATNVVARAHHAQDIDLQLADIRYGHIHQWTSQACQQKGKLTVAQSEWLDRVLLNRWVGIPFFLLMMYLMFLFAINVGSAFIDFFDIMGGALFVDGVHHLLGLVNAPEWVGAILAGGFGVGLQTVATFIPVIGCLYLFLAVLESSGYLARAAFVVDALMRRLGLPGKAFVPMLMGFGCTVPSVMATRTLNSERERLMTSAMAPFMSCGARLPVYALFAVAFFPESGQNLVFGLYLVGILVAVLTGLLLRNTLLPGKSDSMLMEMPDYEWPRPINVGIKTWQKLKSFVFGAGKTIVLVVAVLSVLNSLGTDGSFGHQDQESSVLSKVSQAVTPVLHPIGVRDDNWQATVGIVTGIFAKEAVVGTLNSLYAGGSGDGEESEYSLVASFHEAIAAVAANLAEINPSDPMGISVGELDDQQAAAEAQEVDVSTYGNMQTHFDGAAGAFAYLLFVLLYMPCAAAMGALVRETGRQWALLTAAWCNYTAFLCATVFYQAATFAAHPEQSLFWIGSYGLSLLLLWWLGRRHGDIVARKVVAL
>NZ_CP047374.1|WP_017412111.1|4432885_4433128_+|LuxR-family-transcriptional-regulator
MILRELGDYLAVQRKVSRRDLARHFHTSEDAVEAMLGVWMRKGRVAKRETQICGGSCCGKSQEVMFEWCEPGQIGLVQKR

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

4502 : 83677

Escherichia_phage(22.22%)

tRNA,transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_076611341.1\|4502_5420_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_005315394.1\|7008_7815_+	crotonase/enoyl-CoA hydratase family protein	NA	NA	NA	NA
WP_088814226.1\|7894_9394_-	alanine:cation symporter family protein	NA	NA	NA	NA
WP_005315396.1\|9694_10132_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_159364526.1\|11046_11643_-	hypothetical protein	NA	NA	NA	NA
WP_042467892.1\|12312_15204_-	DUF748 domain-containing protein	NA	NA	NA	NA
WP_058406839.1\|15252_16014_-	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_088814343.1\|16256_17393_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_076611341.1\|18457_19375_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_005315093.1\|20149_21730_+	Na+/H+ antiporter NhaC family protein	NA	NA	NA	NA
WP_005315094.1\|21834_22416_+	thymidine kinase	A0A0F6TIQ8	Escherichia_coli_O157_typing_phage	1.6e-48	52.7
WP_011898640.1\|23964_24426_+	YbjN domain-containing protein	NA	NA	NA	NA
WP_159364527.1\|25119_26223_-	alanine racemase	A0A0P0YM39	Yellowstone_lake_mimivirus	7.5e-31	31.1
WP_159364528.1\|26834_27026_+	hypothetical protein	NA	NA	NA	NA
WP_076611341.1\|27048_27966_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_159364529.1\|29814_30948_+	hydrogenase 2 small subunit	NA	NA	NA	NA
WP_159364530.1\|30950_31958_+	hydrogenase 2 operon protein HybA	A0A077SL61	Escherichia_phage	7.1e-20	29.4
WP_005315106.1\|31950_33138_+	Ni/Fe-hydrogenase cytochrome b subunit	NA	NA	NA	NA
WP_005315108.1\|33134_34838_+	hydrogenase 2 large subunit	NA	NA	NA	NA
WP_042468245.1\|34837_35338_+	HyaD/HybD family hydrogenase maturation endopeptidase	NA	NA	NA	NA
WP_005315112.1\|35319_35847_+	hydrogenase-2 assembly chaperone	NA	NA	NA	NA
WP_088814218.1\|35962_37570_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_011898645.1\|37554_38565_+	ABC transporter permease	NA	NA	NA	NA
WP_005315119.1\|38554_39370_+	ABC transporter permease	NA	NA	NA	NA
WP_042468243.1\|39363_40152_+	ATP-binding cassette domain-containing protein	A0A285PWH2	Cedratvirus	1.5e-09	32.6
WP_005315125.1\|40151_40793_+	ATP-binding cassette domain-containing protein	NA	NA	NA	NA
WP_042468242.1\|41009_42065_-	hydrogenase nickel incorporation protein HypB	NA	NA	NA	NA
WP_005315136.1\|42066_42408_-	hydrogenase maturation nickel metallochaperone HypA	NA	NA	NA	NA
WP_159364531.1\|42417_43422_-	hydrogenase expression/formation protein HypE	NA	NA	NA	NA
WP_159364532.1\|43507_44626_-	hydrogenase formation protein HypD	NA	NA	NA	NA
WP_005315143.1\|44619_44871_-	HypC/HybG/HupF family hydrogenase formation chaperone	NA	NA	NA	NA
WP_042468241.1\|44876_47303_-	carbamoyltransferase HypF	NA	NA	NA	NA
WP_042468240.1\|47299_49219_-	selenocysteine-specific translation elongation factor	A0A2K9KZ60	Tupanvirus	1.7e-14	27.2
WP_005315148.1\|49223_50693_-\|tRNA	L-seryl-tRNA(Sec) selenium transferase	NA	NA	NA	NA
WP_005315151.1\|51265_51757_-	hydrogenase maturation peptidase HycI	NA	NA	NA	NA
WP_005315153.1\|51756_52170_-	HycH family protein	NA	NA	NA	NA
WP_159364533.1\|52162_52978_-	NADH-quinone oxidoreductase subunit NuoB	NA	NA	NA	NA
WP_042468239.1\|52977_53535_-	4Fe-4S dicluster domain-containing protein	NA	NA	NA	NA
WP_005315165.1\|53544_55263_-	hydrogenase large subunit	NA	NA	NA	NA
WP_011898650.1\|55342_56296_-	hydrogenase 3 membrane subunit	NA	NA	NA	NA
WP_042468238.1\|56297_58181_-	hydrogenase 4 subunit B	NA	NA	NA	NA
WP_042468237.1\|58180_58876_-	4Fe-4S dicluster domain-containing protein	NA	NA	NA	NA
WP_159364534.1\|59412_61281_-	low affinity potassium transporter Kup	M1HZV6	Acanthocystis_turfacea_Chlorella_virus	4.9e-67	31.3
WP_076611341.1\|61539_62457_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_159364535.1\|63263_63422_-	hypothetical protein	NA	NA	NA	NA
WP_076611341.1\|63451_64369_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_159364953.1\|64743_65958_-\|transposase	IS256-like element ISAs3 family transposase	A0A218MNI5	uncultured_virus	4.3e-48	47.9
WP_088814405.1\|66023_67286_-\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_005321603.1\|67485_67911_-	chaperonin	NA	NA	NA	NA
WP_034283822.1\|68107_69499_+	T3SS effector protein-tyrosine-phosphatase AopH	NA	NA	NA	NA
WP_076611341.1\|70332_71250_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_085941484.1\|72065_73216_-\|transposase	IS3-like element ISAs32 family transposase	U5P429	Shigella_phage	3.1e-96	63.4
WP_085941483.1\|73963_75241_-	ROK family protein	NA	NA	NA	NA
WP_159364537.1\|75182_76328_-	N-acetylglucosamine-6-phosphate deacetylase	NA	NA	NA	NA
WP_088814201.1\|76337_77138_-	glucosamine-6-phosphate deaminase	NA	NA	NA	NA
WP_058406585.1\|79004_81668_+	family 20 glycosylhydrolase	NA	NA	NA	NA
WP_005309688.1\|82015_83677_+\|tRNA	glutamine--tRNA ligase	A0A222YZ70	Escherichia_phage	7.8e-266	79.5

DBSCAN-SWA_2

483417 : 591684

Burkholderia_virus(14.29%)

integrase,protease,transposase

attL 564679:564693|attR 593317:593331

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_076611341.1\|483417_484335_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_005311027.1\|486395_486887_-	hypothetical protein	NA	NA	NA	NA
WP_005311031.1\|487119_487317_+	DUF4250 domain-containing protein	NA	NA	NA	NA
WP_159364601.1\|487704_490182_+	glycogen/starch/alpha-glucan family phosphorylase	Q8B3H5	Iris_mild_mosaic_virus	2.0e-15	47.1
WP_017412837.1\|490245_491631_-	DASS family sodium-coupled anion symporter	NA	NA	NA	NA
WP_005311038.1\|491795_492224_-	thioredoxin TrxC	A0A1J0GW78	Streptomyces_phage	9.7e-11	37.6
WP_159364602.1\|492365_495179_+	response regulator	A0A1V0SGX0	Hokovirus	6.7e-68	34.7
WP_005311041.1\|497108_498860_+	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	1.0e-45	29.7
WP_085941617.1\|498979_499489_+	DUF4442 domain-containing protein	NA	NA	NA	NA
WP_005311045.1\|499634_499868_-	ribosome-associated protein YbcJ	NA	NA	NA	NA
WP_159364603.1\|500043_500448_-	enoyl-CoA hydratase	NA	NA	NA	NA
WP_159364604.1\|500444_502229_-	class I poly(R)-hydroxyalkanoic acid synthase	NA	NA	NA	NA
WP_005311051.1\|502322_502673_-	phasin family protein	NA	NA	NA	NA
WP_005311053.1\|502990_503554_+	hypothetical protein	NA	NA	NA	NA
WP_011898780.1\|503632_504388_+	DUF429 domain-containing protein	NA	NA	NA	NA
WP_034281663.1\|504765_505629_+	pyridoxal kinase PdxY	NA	NA	NA	NA
WP_159364605.1\|505653_505995_-	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_005311062.1\|506112_507231_-	glycerol dehydrogenase	NA	NA	NA	NA
WP_159364606.1\|507476_507983_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_011898778.1\|508179_508611_-	NUDIX domain-containing protein	NA	NA	NA	NA
WP_005311069.1\|508597_509110_-	DUF4823 domain-containing protein	NA	NA	NA	NA
WP_159364966.1\|509189_509450_-	CYTH domain-containing protein	NA	NA	NA	NA
WP_076611341.1\|509468_510386_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_159364607.1\|510882_511191_+	hypothetical protein	NA	NA	NA	NA
WP_005311073.1\|511232_512078_+	hypothetical protein	NA	NA	NA	NA
WP_005311075.1\|512217_512550_+	YnfA family protein	A0A218MNG8	uncultured_virus	2.0e-27	56.7
WP_005311077.1\|512654_513038_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_005311079.1\|513070_513517_+	acetyltransferase	NA	NA	NA	NA
WP_159364608.1\|513588_514980_-	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	2.0e-49	34.1
WP_005311083.1\|515208_515685_-	glutathione peroxidase	A0A1S7DM81	Molluscum_contagiosum_virus	2.1e-14	33.3
WP_159364967.1\|515866_516571_+	SM-20 protein	NA	NA	NA	NA
WP_159364609.1\|516762_517752_+	D-alanine--D-alanine ligase	NA	NA	NA	NA
WP_005311088.1\|517814_518228_-	VOC family protein	NA	NA	NA	NA
WP_005311089.1\|518393_519158_+	DTW domain-containing protein	NA	NA	NA	NA
WP_005311090.1\|519356_520136_+	TSUP family transporter	NA	NA	NA	NA
WP_005311091.1\|520184_521072_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_005311094.1\|523269_524907_+	ATP-dependent endonuclease	NA	NA	NA	NA
WP_017412051.1\|525098_525818_+	hypothetical protein	NA	NA	NA	NA
WP_159364610.1\|525904_527968_-	glycogen debranching protein GlgX	NA	NA	NA	NA
WP_017413057.1\|531160_531841_+	pyrimidine 5'-nucleotidase	NA	NA	NA	NA
WP_155268755.1\|531916_532060_-	hypothetical protein	NA	NA	NA	NA
WP_088814343.1\|532556_533693_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_076611341.1\|533964_534882_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_076611341.1\|535034_535952_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_005311113.1\|536109_536451_-	DUF1353 domain-containing protein	NA	NA	NA	NA
WP_005311115.1\|537125_538013_+	hypothetical protein	NA	NA	NA	NA
WP_159364613.1\|538023_538932_+	hypothetical protein	NA	NA	NA	NA
WP_088814108.1\|539838_540756_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_034283822.1\|541011_542403_+	T3SS effector protein-tyrosine-phosphatase AopH	NA	NA	NA	NA
WP_159364614.1\|543016_544048_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_005315454.1\|544211_544583_+	VOC family protein	NA	NA	NA	NA
WP_011898674.1\|544855_545254_+	GFA family protein	NA	NA	NA	NA
WP_005315459.1\|545275_545560_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_005315464.1\|547057_547582_-	endonuclease SmrB	NA	NA	NA	NA
WP_005315466.1\|547664_548600_+	50S ribosomal protein L3 N(5)-glutamine methyltransferase	NA	NA	NA	NA
WP_005315468.1\|548612_549701_+	chorismate synthase	A0A291AU41	Pandoravirus	7.5e-84	45.6
WP_159364615.1\|549821_550664_-	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_005315472.1\|550987_552391_+	DEAD/DEAH box helicase	A0A0N9Q9J4	Chrysochromulina_ericina_virus	3.4e-44	30.5
WP_005315475.1\|552503_553193_-	RES family NAD+ phosphorylase	NA	NA	NA	NA
WP_159364616.1\|553192_553597_-	DUF2384 domain-containing protein	NA	NA	NA	NA
WP_076611341.1\|554061_554979_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_005322157.1\|555154_555568_+	DUF2158 domain-containing protein	NA	NA	NA	NA
WP_011898689.1\|555726_557703_+\|protease	Lon protease family protein	NA	NA	NA	NA
WP_005315696.1\|557783_558344_+	3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA	NA	NA	NA	NA
WP_010674759.1\|558417_558594_-	ribosome modulation factor	NA	NA	NA	NA
WP_005315688.1\|558756_560391_-	DUF3466 family protein	NA	NA	NA	NA
WP_011898688.1\|560399_562310_-	ABC transporter ATP-binding protein	A0A2K9L3Z8	Tupanvirus	3.2e-53	27.7
WP_005315677.1\|562381_562621_-	thioredoxin family protein	NA	NA	NA	NA
WP_085941607.1\|562620_564789_-	bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL	W6LLI2	Streptococcus_phage	1.9e-14	28.2
564679:564693	attL	NA	NA	NA	NA
WP_076611341.1\|565494_566412_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_042467334.1\|566854_567181_+	helix-turn-helix transcriptional regulator	Q6J1N3	Burkholderia_virus	2.7e-05	33.0
WP_088814376.1\|567579_567828_-	hypothetical protein	NA	NA	NA	NA
WP_042467337.1\|568572_568851_+	hypothetical protein	A4JWW9	Burkholderia_virus	1.8e-10	44.6
WP_017411731.1\|569164_570442_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_159364619.1\|571229_572126_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_005311538.1\|572174_574145_-	SDR family oxidoreductase	A0A2C9DTC1	Eastern_grey_kangaroopox_virus	1.1e-08	30.1
WP_102665712.1\|574390_574969_+	phasin family protein	NA	NA	NA	NA
WP_159364620.1\|575062_576247_+	patatin family protein	NA	NA	NA	NA
WP_005311528.1\|576928_577729_+	hypothetical protein	NA	NA	NA	NA
WP_102665239.1\|577808_579239_-	wax ester/triacylglycerol synthase family O-acyltransferase	NA	NA	NA	NA
WP_085941456.1\|579542_579920_-	poly(3-hydroxybutyrate) depolymerase	NA	NA	NA	NA
WP_005311522.1\|580149_580893_+	hypothetical protein	NA	NA	NA	NA
WP_005311521.1\|580968_582414_-	bifunctional 2-methylcitrate dehydratase/aconitate hydratase	NA	NA	NA	NA
WP_159364621.1\|582424_583552_-	2-methylcitrate synthase	NA	NA	NA	NA
WP_159364622.1\|583563_584439_-	methylisocitrate lyase	NA	NA	NA	NA
WP_005311519.1\|584586_585219_+	paraquat-inducible protein A	NA	NA	NA	NA
WP_005311518.1\|585196_585805_+	paraquat-inducible protein A	NA	NA	NA	NA
WP_159364623.1\|585907_588460_+	MCE family protein	NA	NA	NA	NA
WP_159364624.1\|588591_590010_+	16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF	NA	NA	NA	NA
WP_005311516.1\|590213_590486_-	hypothetical protein	NA	NA	NA	NA
WP_088814231.1\|590655_591684_-\|integrase	site-specific integrase	NA	NA	NA	NA
593317:593331	attR	NA	NA	NA	NA

DBSCAN-SWA_3

726801 : 768584

Synechococcus_phage(100.0%)

integrase,tRNA,transposase

attL 748242:748301|attR 768614:769678

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_076611341.1\|726801_727719_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_159364643.1\|728641_729808_+	lipopolysaccharide heptosyltransferase family protein	NA	NA	NA	NA
WP_102665693.1\|729873_730638_-	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_159364969.1\|730829_733103_-	5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase	NA	NA	NA	NA
WP_159364644.1\|734142_734907_-	siderophore ferric iron reductase	NA	NA	NA	NA
WP_005310925.1\|735002_737138_-	TonB-dependent siderophore receptor	NA	NA	NA	NA
WP_085941620.1\|737430_738423_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_005310923.1\|738633_739374_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_021138227.1\|739459_740365_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_005310920.1\|741547_742618_+	isopenicillin N synthase family oxygenase	NA	NA	NA	NA
WP_159364645.1\|742714_743878_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_076611341.1\|746376_747294_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_011898763.1\|747893_748205_-	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
748242:748301	attL	NA	NA	NA	NA
WP_076611341.1\|748330_749248_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_005311149.1\|749597_750110_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_085941615.1\|750322_750700_-	septal ring lytic transglycosylase RlpA family protein	F5B3X9	Synechococcus_phage	1.1e-15	52.5
WP_159364647.1\|750952_755380_-	chromosome partition protein MukB	NA	NA	NA	NA
WP_005311141.1\|755407_756145_-	chromosome partition protein MukE	NA	NA	NA	NA
WP_005311139.1\|756125_757460_-	chromosome partition protein MukF	NA	NA	NA	NA
WP_005311137.1\|757553_758330_-\|tRNA	tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM	NA	NA	NA	NA
WP_034281583.1\|758458_759229_+	envelope biogenesis factor ElyC	NA	NA	NA	NA
WP_005311133.1\|759364_760120_+	triose-phosphate isomerase	NA	NA	NA	NA
WP_005311131.1\|760267_761239_+	6-phosphofructokinase	NA	NA	NA	NA
WP_088814108.1\|763556_764474_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_017413136.1\|764564_764873_-	hypothetical protein	NA	NA	NA	NA
WP_005320977.1\|764894_765395_-	hypothetical protein	NA	NA	NA	NA
WP_017413138.1\|765421_765775_-	hypothetical protein	NA	NA	NA	NA
WP_005320982.1\|765852_766266_-	PIN domain-containing protein	NA	NA	NA	NA
WP_005320985.1\|766262_766493_-	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_017413139.1\|766561_766948_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_159368364.1\|766860_767250_-	hypothetical protein	NA	NA	NA	NA
WP_076611341.1\|767666_768584_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
768614:769678	attR	NA	NA	NA	NA

DBSCAN-SWA_4

890259 : 924631

uncultured_Mediterranean_phage(18.18%)

bacteriocin,protease,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_159364670.1\|890259_891006_-\|tRNA	tRNA-(ms[2]io[6]A)-hydroxylase	NA	NA	NA	NA
WP_005310748.1\|891229_892750_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.2e-87	42.4
WP_005310746.1\|892771_893260_-\|bacteriocin	bacteriocin production protein	NA	NA	NA	NA
WP_005310745.1\|893447_894743_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	7.5e-91	43.0
WP_017411682.1\|895099_896443_-	replication-associated recombination protein A	G3MBE0	Bacillus_virus	3.4e-78	41.2
WP_042467874.1\|896561_897170_-	outer membrane lipoprotein chaperone LolA	NA	NA	NA	NA
WP_159364671.1\|897247_899773_-	cell division protein FtsK	A0A218M9A2	Mycobacterium_phage	1.6e-89	49.3
WP_005300047.1\|899975_900467_-	leucine-responsive transcriptional regulator Lrp	NA	NA	NA	NA
WP_073536599.1\|901131_901323_+	hypothetical protein	NA	NA	NA	NA
WP_005310734.1\|901541_902492_+	thioredoxin-disulfide reductase	A0A2I2L5E1	Orpheovirus	9.5e-59	42.8
WP_005310731.1\|903899_904370_-	glycine zipper 2TM domain-containing protein	NA	NA	NA	NA
WP_005310730.1\|904389_905097_+\|tRNA	leucyl/phenylalanyl-tRNA--protein transferase	NA	NA	NA	NA
WP_159364672.1\|905093_905798_+	arginyltransferase	NA	NA	NA	NA
WP_005300033.1\|905866_906085_+	translation initiation factor IF-1	NA	NA	NA	NA
WP_005310727.1\|906153_908406_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	1.2e-168	43.1
WP_005310725.1\|908465_908783_-\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	5.3e-14	48.1
WP_005300025.1\|909012_909231_+	cold shock-like protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	1.2e-17	63.2
WP_005310722.1\|909341_910205_-	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	8.7e-27	30.9
WP_005310720.1\|910761_911013_-	hypothetical protein	NA	NA	NA	NA
WP_085941623.1\|911063_911799_-\|transposase	IS1-like element ISAs8 family transposase	A0A0U2RK18	Escherichia_phage	5.8e-80	65.2
WP_005310714.1\|912110_912398_-	type VI secretion system PAAR protein	G4KK81	Yersinia_phage	4.6e-09	39.4
WP_005310712.1\|912430_912616_+	hypothetical protein	NA	NA	NA	NA
WP_159364673.1\|912689_914126_-	hypothetical protein	NA	NA	NA	NA
WP_005310708.1\|919049_919655_-	type VI secretion system-associated protein TagO	NA	NA	NA	NA
WP_005310706.1\|919654_921193_-	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_155268744.1\|921195_921336_-	hypothetical protein	NA	NA	NA	NA
WP_076611341.1\|922635_923553_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_159364674.1\|923575_923731_-	hypothetical protein	NA	NA	NA	NA
WP_076611341.1\|923713_924631_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA

DBSCAN-SWA_5

930261 : 1082698

119

uncultured_Caudovirales_phage(17.65%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_076611341.1\|930261_931179_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_005310661.1\|932207_932405_-	hypothetical protein	NA	NA	NA	NA
WP_017412578.1\|932500_933397_-	DMT family transporter	NA	NA	NA	NA
WP_005310657.1\|933509_934091_+	electron transport complex subunit RsxA	NA	NA	NA	NA
WP_017412577.1\|934095_934659_+	electron transport complex subunit RsxB	NA	NA	NA	NA
WP_042468140.1\|934673_936953_+	electron transport complex subunit RsxC	NA	NA	NA	NA
WP_159364675.1\|936956_938009_+	electron transport complex subunit RsxD	NA	NA	NA	NA
WP_005310649.1\|938132_938765_+	electron transport complex subunit RsxG	NA	NA	NA	NA
WP_017412575.1\|938838_939597_+	electron transport complex subunit E	NA	NA	NA	NA
WP_005310645.1\|939615_940257_+	endonuclease III	NA	NA	NA	NA
WP_005310643.1\|940359_940773_+	lactoylglutathione lyase	NA	NA	NA	NA
WP_159364971.1\|940845_941709_-	OmpA family protein	NA	NA	NA	NA
WP_159364676.1\|941789_943763_-	chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	1.9e-32	32.8
WP_085941471.1\|943848_944583_+	ribonuclease T	NA	NA	NA	NA
WP_159364677.1\|944834_946157_+	TRAP transporter large permease subunit	NA	NA	NA	NA
WP_159364972.1\|946425_947640_-\|transposase	IS256-like element ISAs3 family transposase	A0A218MNI5	uncultured_virus	4.3e-48	47.9
WP_159364678.1\|949536_950010_-	molybdopterin-binding oxidoreductase	NA	NA	NA	NA
WP_017412353.1\|950344_952222_-	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	2.6e-60	36.4
WP_005310625.1\|952403_952865_-	hotdog fold thioesterase	NA	NA	NA	NA
WP_005310623.1\|952969_953458_-	hypothetical protein	NA	NA	NA	NA
WP_159364973.1\|953457_956649_-	FAD-binding protein	NA	NA	NA	NA
WP_042468147.1\|956704_957616_+	cation diffusion facilitator family transporter	NA	NA	NA	NA
WP_042468148.1\|957902_959438_+	TerC family protein	A0A0R6PEZ3	Moraxella_phage	2.0e-37	41.7
WP_005310617.1\|959614_960736_+	alkene reductase	NA	NA	NA	NA
WP_005310615.1\|960837_961857_-	adenosine deaminase	NA	NA	NA	NA
WP_017412358.1\|962076_962826_+	HAD-IIA family hydrolase	NA	NA	NA	NA
WP_005310611.1\|962846_964466_+	cation:proton antiporter	NA	NA	NA	NA
WP_005310609.1\|964555_964924_+	DUF861 domain-containing protein	NA	NA	NA	NA
WP_159364679.1\|965117_966782_+	asparagine synthase B	H8ZJK1	Ostreococcus_tauri_virus	8.2e-90	40.6
WP_005310605.1\|966904_968401_-	C69 family dipeptidase	NA	NA	NA	NA
WP_159364327.1\|969513_970431_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_005310595.1\|970727_971228_+	thioredoxin family protein	NA	NA	NA	NA
WP_005310593.1\|971289_971913_+	glutathione S-transferase	NA	NA	NA	NA
WP_088814258.1\|971996_972668_-	maleylacetoacetate isomerase	NA	NA	NA	NA
WP_088814259.1\|972708_973707_-	fumarylacetoacetate hydrolase family protein	NA	NA	NA	NA
WP_139697064.1\|974864_975977_-	4-hydroxyphenylpyruvate dioxygenase	NA	NA	NA	NA
WP_005310586.1\|976235_976868_-	haloacid dehalogenase-like hydrolase	NA	NA	NA	NA
WP_011898835.1\|976885_977545_-	TIGR01621 family pseudouridine synthase	NA	NA	NA	NA
WP_076611341.1\|978154_979072_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_005310581.1\|980426_981989_-	methyl-accepting chemotaxis protein	A0A1B0V854	Salmonella_phage	5.6e-32	45.3
WP_011898838.1\|982481_983138_+	Bax inhibitor-1/YccA family protein	A0A2H4JFM9	uncultured_Caudovirales_phage	4.0e-48	53.1
WP_042468686.1\|983302_985456_+	TIGR01666 family membrane protein	NA	NA	NA	NA
WP_005310577.1\|985482_985824_+	TusE/DsrC/DsvC family sulfur relay protein	NA	NA	NA	NA
WP_042468689.1\|985882_986653_-	cell division protein DedD	NA	NA	NA	NA
WP_088814262.1\|986853_988101_-	bifunctional tetrahydrofolate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_005310570.1\|988115_988979_-	acetyl-CoA carboxylase carboxyltransferase subunit beta	NA	NA	NA	NA
WP_042468693.1\|989098_989908_-\|tRNA	tRNA pseudouridine(38-40) synthase TruA	NA	NA	NA	NA
WP_011898842.1\|990074_992213_-	pilus assembly protein TapV	NA	NA	NA	NA
WP_005310564.1\|992491_993508_-	aspartate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_159364680.1\|993675_994809_-	DUF3410 domain-containing protein	NA	NA	NA	NA
WP_042468696.1\|995177_995900_+	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_159364681.1\|995984_996815_-	hypothetical protein	NA	NA	NA	NA
WP_076611341.1\|997623_998541_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_076611341.1\|999707_1000625_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_076611341.1\|1000857_1001775_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_159364974.1\|1001838_1002831_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_005310548.1\|1005697_1006159_-	hypothetical protein	NA	NA	NA	NA
WP_011898844.1\|1006177_1008055_-	S8 family serine peptidase	A0A1V0S9L2	Catovirus	5.2e-16	20.8
WP_159364683.1\|1008583_1009501_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_076611341.1\|1009933_1010851_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_159364684.1\|1010895_1013295_-	phosphoenolpyruvate synthase	A0A1V0SGR7	Hokovirus	3.1e-175	38.0
WP_005310537.1\|1013621_1014434_+	kinase/pyrophosphorylase	NA	NA	NA	NA
WP_005310536.1\|1014557_1014845_-	hypothetical protein	NA	NA	NA	NA
WP_042469111.1\|1015209_1016586_+	amino acid permease	NA	NA	NA	NA
WP_058394668.1\|1018131_1018599_+	hypothetical protein	NA	NA	NA	NA
WP_005310510.1\|1018830_1019316_+	hypothetical protein	NA	NA	NA	NA
WP_005310508.1\|1019437_1019887_+	hypothetical protein	NA	NA	NA	NA
WP_159364685.1\|1019990_1022888_+	hypothetical protein	NA	NA	NA	NA
WP_005310504.1\|1022887_1023727_+	hypothetical protein	NA	NA	NA	NA
WP_005310502.1\|1023829_1025254_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_005310500.1\|1025289_1025850_+	hypothetical protein	NA	NA	NA	NA
WP_042468587.1\|1025870_1027184_+	hypothetical protein	NA	NA	NA	NA
WP_005310495.1\|1027280_1028927_+	hypothetical protein	NA	NA	NA	NA
WP_017412350.1\|1029052_1030255_+	Bcr/CflA family multidrug efflux MFS transporter	S4TR35	Salmonella_phage	1.8e-22	25.1
WP_159364686.1\|1030375_1031785_-	sodium:proton antiporter	NA	NA	NA	NA
WP_005310491.1\|1031894_1032362_-	DUF4357 domain-containing protein	NA	NA	NA	NA
WP_042468585.1\|1032559_1033240_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	8.7e-30	35.9
WP_042468584.1\|1033267_1035709_+	FtsX-like permease family protein	NA	NA	NA	NA
WP_159364687.1\|1035663_1036773_+	carotenoid 1,2-hydratase	NA	NA	NA	NA
WP_011898849.1\|1036972_1037926_-	hypothetical protein	NA	NA	NA	NA
WP_042468582.1\|1038445_1038934_+	MgtC/SapB family protein	G3MA03	Bacillus_virus	7.4e-15	39.8
WP_159364327.1\|1040386_1041304_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_073531738.1\|1042231_1042846_+	hypothetical protein	NA	NA	NA	NA
WP_005310476.1\|1043109_1043901_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_159364683.1\|1044057_1044975_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_005310474.1\|1045078_1045435_+	MmcQ/YjbR family DNA-binding protein	NA	NA	NA	NA
WP_085941476.1\|1045953_1046310_+	DUF3802 family protein	NA	NA	NA	NA
WP_017411371.1\|1046665_1047298_-	peptide-methionine (S)-S-oxide reductase MsrA	NA	NA	NA	NA
WP_017411372.1\|1047568_1048897_+	amino-acid N-acetyltransferase	NA	NA	NA	NA
WP_058406197.1\|1050771_1051860_-	hypothetical protein	NA	NA	NA	NA
WP_005310455.1\|1056714_1057473_-	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_005310453.1\|1057641_1057959_-	heavy metal-binding domain-containing protein	NA	NA	NA	NA
WP_005310451.1\|1058166_1059459_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_085941477.1\|1059537_1060173_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_011899080.1\|1060485_1061517_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_159364689.1\|1062617_1062785_-	hypothetical protein	NA	NA	NA	NA
WP_076611341.1\|1062767_1063685_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_005315078.1\|1063845_1064253_+	H-NS histone family protein	NA	NA	NA	NA
WP_042468675.1\|1064319_1064883_-	cob(I)yrinic acid a,c-diamide adenosyltransferase	NA	NA	NA	NA
WP_005315061.1\|1064879_1065110_-	DUF3820 family protein	NA	NA	NA	NA
WP_085941448.1\|1065111_1065825_-	7-carboxy-7-deazaguanine synthase QueE	A0A2I7S8X1	Vibrio_phage	1.4e-17	39.4
WP_034282960.1\|1065844_1066552_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	2.9e-84	67.1
WP_085941447.1\|1066575_1067265_-	DTW domain-containing protein	NA	NA	NA	NA
WP_005315050.1\|1067215_1067773_+	rhombosortase	NA	NA	NA	NA
WP_159364690.1\|1067846_1068548_-	orotidine-5'-phosphate decarboxylase	NA	NA	NA	NA
WP_005315046.1\|1068658_1069825_-	lipopolysaccharide assembly protein LapB	NA	NA	NA	NA
WP_005315045.1\|1069834_1070119_-	DUF1049 domain-containing protein	NA	NA	NA	NA
WP_159364691.1\|1070275_1070560_-	integration host factor subunit beta	A0A0H3UZA0	Geobacillus_virus	2.2e-11	37.8
WP_159364692.1\|1070652_1072323_-	30S ribosomal protein S1	NA	NA	NA	NA
WP_005315040.1\|1072417_1073110_-	(d)CMP kinase	NA	NA	NA	NA
WP_005315038.1\|1073358_1073952_+	GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	1.3e-42	46.5
WP_159364693.1\|1074097_1075072_-	HTH-type transcriptional regulator CysB	NA	NA	NA	NA
WP_139696973.1\|1075145_1076021_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_005315028.1\|1076114_1077323_+	MFS transporter	NA	NA	NA	NA
WP_085941598.1\|1077367_1077913_-	hypothetical protein	NA	NA	NA	NA
WP_005315024.1\|1077915_1078680_-	hypothetical protein	NA	NA	NA	NA
WP_005315023.1\|1078869_1079595_-	oxygen-insensitive NADPH nitroreductase	NA	NA	NA	NA
WP_042468681.1\|1079685_1081623_-	EAL domain-containing protein	G3MA91	Bacillus_virus	6.3e-17	32.1
WP_011899080.1\|1081666_1082698_-\|transposase	IS630 family transposase	NA	NA	NA	NA

DBSCAN-SWA_6

1091154 : 1235038

104

Tupanvirus(25.0%)

protease,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_076611341.1\|1091154_1092072_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_005315309.1\|1092781_1094152_+	exodeoxyribonuclease VII large subunit	A0A2H4UVM9	Bodo_saltans_virus	5.3e-34	36.7
WP_005315308.1\|1094216_1095584_-	heme anaerobic degradation radical SAM methyltransferase ChuW/HutW	NA	NA	NA	NA
WP_088814220.1\|1095831_1097442_+	HAMP domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	1.6e-26	40.8
WP_005315306.1\|1097535_1098591_-	3-deoxy-7-phosphoheptulonate synthase AroG	A0A0B6VT43	Edwardsiella_phage	5.2e-82	48.9
WP_159364694.1\|1098819_1100103_-	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_005315304.1\|1100273_1101362_-	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	1.1e-87	46.9
WP_005315303.1\|1101586_1102516_-	electron transfer flavoprotein subunit alpha	NA	NA	NA	NA
WP_085941450.1\|1102610_1103372_-	electron transfer flavoprotein subunit beta/FixA family protein	NA	NA	NA	NA
WP_005315298.1\|1103489_1105139_+	electron transfer flavoprotein-ubiquinone oxidoreductase	NA	NA	NA	NA
WP_100766231.1\|1105151_1105244_+	hypothetical protein	NA	NA	NA	NA
WP_005315297.1\|1105594_1106542_+	magnesium/cobalt transporter CorA	NA	NA	NA	NA
WP_017412312.1\|1106693_1107155_+	DUF2919 domain-containing protein	NA	NA	NA	NA
WP_042468070.1\|1107170_1107923_-	hypothetical protein	NA	NA	NA	NA
WP_042468071.1\|1108179_1109418_+	siderophore amonabactin export MFS transporter	NA	NA	NA	NA
WP_042468072.1\|1109475_1111449_+	siderophore amonabactin TonB-dependent receptor	A0A0P0I887	Acinetobacter_phage	2.4e-16	34.9
WP_005315288.1\|1111519_1112536_+	amonabactin ABC transporter permease subunit 2	NA	NA	NA	NA
WP_011898657.1\|1112550_1113618_+	amonabactin ABC transporter permease subunit 1	NA	NA	NA	NA
WP_017412316.1\|1113617_1114433_+	amonabactin ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.3e-13	25.3
WP_005315278.1\|1114491_1115217_-	amonabactin biosynthesis phosphopantetheinyl transferase AmoD	NA	NA	NA	NA
WP_005315275.1\|1115375_1116320_+	amonabactin ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_159364695.1\|1116402_1118013_-	amonabactin biosynthesis glycine adenylation protein AmoH	A0A2K9L3I8	Tupanvirus	5.8e-40	27.9
WP_159368365.1\|1118009_1124270_-	amonabactin biosynthesis non-ribosomal peptide synthetase AmoG	A0A2K9KZV5	Tupanvirus	5.5e-70	24.2
WP_005315268.1\|1124278_1125028_-	2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase	NA	NA	NA	NA
WP_159368366.1\|1125057_1128153_-	amonabactin biosynthesis non-ribosomal peptide synthetase AmoF	A0A2K9L3I8	Tupanvirus	7.0e-42	25.2
WP_005315266.1\|1128149_1129058_-	isochorismatase family protein	NA	NA	NA	NA
WP_042468075.1\|1129082_1130753_-	(2,3-dihydroxybenzoyl)adenylate synthase	NA	NA	NA	NA
WP_034282536.1\|1130749_1131943_-	isochorismate synthase	NA	NA	NA	NA
WP_005315260.1\|1132267_1132819_+	lipoprotein	NA	NA	NA	NA
WP_159364697.1\|1132965_1134966_+	hypothetical protein	NA	NA	NA	NA
WP_005315254.1\|1136525_1138169_+	EAL domain-containing protein	NA	NA	NA	NA
WP_005315253.1\|1138131_1138626_-	hypothetical protein	NA	NA	NA	NA
WP_005315249.1\|1138806_1139169_-	DUF2750 domain-containing protein	NA	NA	NA	NA
WP_100224073.1\|1139282_1141076_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	2.5e-23	38.0
WP_042468808.1\|1141072_1142377_-	inosine/guanosine kinase	NA	NA	NA	NA
WP_159364975.1\|1142563_1142956_-	hypothetical protein	NA	NA	NA	NA
WP_080697425.1\|1143027_1144056_-	ferrochelatase	NA	NA	NA	NA
WP_017412939.1\|1144107_1144752_-	adenylate kinase	NA	NA	NA	NA
WP_005315220.1\|1144798_1144993_-	hypothetical protein	NA	NA	NA	NA
WP_005315218.1\|1145009_1146923_-	molecular chaperone HtpG	A0A1B1ISV4	uncultured_Mediterranean_phage	4.5e-116	36.5
WP_005315205.1\|1147937_1148762_-	formate dehydrogenase accessory sulfurtransferase FdhD	NA	NA	NA	NA
WP_159364698.1\|1148774_1150889_-	GAF domain-containing protein	NA	NA	NA	NA
WP_005315184.1\|1151251_1151650_-	hypothetical protein	NA	NA	NA	NA
WP_159364699.1\|1151716_1152853_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_011898652.1\|1153016_1155161_-	formate dehydrogenase H subunit alpha, selenocysteine-containing	NA	NA	NA	NA
WP_076611341.1\|1156278_1157196_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_159368367.1\|1157244_1159290_-	acyltransferase domain-containing protein	D0R7J2	Paenibacillus_phage	4.9e-20	45.2
WP_088814343.1\|1159835_1160972_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_159364701.1\|1160980_1161154_-	hypothetical protein	NA	NA	NA	NA
WP_088814108.1\|1161323_1162241_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_159364703.1\|1162244_1164170_-	AMP-binding protein	A0A2K9L3I8	Tupanvirus	3.0e-51	27.3
WP_159364704.1\|1164199_1165420_-	hypothetical protein	NA	NA	NA	NA
WP_042468945.1\|1168438_1170064_-	phosphoethanolamine--lipid A transferase	NA	NA	NA	NA
WP_005313105.1\|1170468_1171209_-	YebC/PmpR family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_042468944.1\|1171301_1173068_-\|tRNA	aspartate--tRNA ligase	NA	NA	NA	NA
WP_088814108.1\|1173825_1174743_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_005313097.1\|1175695_1176439_+	carboxy-S-adenosyl-L-methionine synthase CmoA	NA	NA	NA	NA
WP_005313094.1\|1176442_1177420_+\|tRNA	tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic acid(34) synthase CmoB	NA	NA	NA	NA
WP_085941630.1\|1177544_1178261_+\|protease	ATP-dependent zinc protease	NA	NA	NA	NA
WP_005313088.1\|1178264_1179803_+	inactive transglutaminase family protein	NA	NA	NA	NA
WP_005313085.1\|1179806_1180772_+	alpha-L-glutamate ligase-like protein	NA	NA	NA	NA
WP_042469000.1\|1180918_1181521_-	peroxiredoxin C	NA	NA	NA	NA
WP_088814343.1\|1181726_1182863_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_159364976.1\|1182966_1184001_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_088814193.1\|1184016_1184748_-	protein phosphatase CheZ	NA	NA	NA	NA
WP_005319295.1\|1184760_1185144_-	chemotaxis protein CheY	Q56AR1	Bacillus_thuringiensis_phage	4.4e-07	32.8
WP_005319297.1\|1185255_1185975_-	RNA polymerase sigma factor FliA	NA	NA	NA	NA
WP_088814192.1\|1186003_1186837_-	MinD/ParA family protein	NA	NA	NA	NA
WP_005319300.1\|1186844_1188263_-	flagellar biosynthesis protein FlhF	NA	NA	NA	NA
WP_159364705.1\|1188279_1190382_-	flagellar biosynthesis protein FlhA	NA	NA	NA	NA
WP_042468830.1\|1190489_1191335_-	flagellar biosynthesis protein FlhB	NA	NA	NA	NA
WP_042468835.1\|1191421_1192219_-	flagellar type III secretion system protein FliR	NA	NA	NA	NA
WP_005319310.1\|1192298_1192568_-	flagellar biosynthesis protein FliQ	NA	NA	NA	NA
WP_034282679.1\|1192595_1193375_-	flagellar type III secretion system pore protein FliP	NA	NA	NA	NA
WP_005319315.1\|1193361_1193745_-	flagellar biosynthetic protein FliO	NA	NA	NA	NA
WP_017412373.1\|1193806_1194199_-	flagellar motor switch protein FliN	NA	NA	NA	NA
WP_005319319.1\|1194248_1195319_-	flagellar motor switch protein FliM	NA	NA	NA	NA
WP_017412372.1\|1195328_1195847_-	flagellar basal body-associated protein FliL	NA	NA	NA	NA
WP_159364706.1\|1199757_1200564_-	flagellar assembly protein FliH	NA	NA	NA	NA
WP_017412370.1\|1200632_1201694_-	flagellar motor switch protein FliG	NA	NA	NA	NA
WP_159364977.1\|1201686_1203372_-	flagellar basal body M-ring protein FliF	NA	NA	NA	NA
WP_011898507.1\|1203448_1203766_-	flagellar hook-basal body complex protein FliE	NA	NA	NA	NA
WP_005319340.1\|1203923_1204832_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_159364707.1\|1204898_1206650_+	amidohydrolase family protein	NA	NA	NA	NA
WP_159364708.1\|1206742_1207528_-	hypothetical protein	NA	NA	NA	NA
WP_005319346.1\|1207726_1208095_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_005319348.1\|1208346_1208655_+	DUF134 domain-containing protein	NA	NA	NA	NA
WP_005319350.1\|1208651_1209176_+	hypothetical protein	NA	NA	NA	NA
WP_005319352.1\|1209160_1209343_+	hypothetical protein	NA	NA	NA	NA
WP_102665398.1\|1209382_1210579_-	HD domain-containing protein	NA	NA	NA	NA
WP_005319357.1\|1210811_1212140_+	30S ribosomal protein S12 methylthiotransferase RimO	NA	NA	NA	NA
WP_005319359.1\|1212302_1212770_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_021138415.1\|1213918_1215277_+	GHKL domain-containing protein	NA	NA	NA	NA
WP_159364709.1\|1215650_1216619_-	glucokinase	NA	NA	NA	NA
WP_159364710.1\|1216959_1217823_+	transcriptional regulator HexR	NA	NA	NA	NA
WP_017412636.1\|1217986_1219426_+	pyruvate kinase	NA	NA	NA	NA
WP_005319373.1\|1219486_1220533_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_042468563.1\|1220548_1223614_-	efflux RND transporter permease subunit	S5VTK5	Leptospira_phage	3.3e-68	25.2
WP_005319376.1\|1223788_1226113_-	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_005319378.1\|1226161_1226815_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_159364699.1\|1227649_1228786_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_088814343.1\|1229719_1230856_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_076611341.1\|1231731_1232649_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_005314540.1\|1233661_1235038_-\|tRNA	cysteine--tRNA ligase	M1PG92	Moumouvirus	8.7e-45	33.5

DBSCAN-SWA_7

1310267 : 1344325

Morganella_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_076611341.1\|1310267_1311185_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_076611341.1\|1311762_1312680_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_159364980.1\|1312783_1313587_+	flagellar basal body P-ring formation protein FlgA	NA	NA	NA	NA
WP_005320221.1\|1313677_1313998_+	flagellar biosynthesis anti-sigma factor FlgM	NA	NA	NA	NA
WP_005320223.1\|1313997_1314411_+	flagellar protein FlgN	NA	NA	NA	NA
WP_005320225.1\|1314454_1314997_-	phosphodiesterase	NA	NA	NA	NA
WP_042467270.1\|1315008_1316661_-	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_017412806.1\|1316900_1317797_+	DMT family transporter	NA	NA	NA	NA
WP_005320231.1\|1317832_1318525_-	16S rRNA pseudouridine(516) synthase RsuA	NA	NA	NA	NA
WP_159364727.1\|1318698_1319895_+	HD domain-containing protein	NA	NA	NA	NA
WP_076611341.1\|1320064_1320982_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_017412982.1\|1321336_1322230_+	EamA family transporter	NA	NA	NA	NA
WP_042469080.1\|1324317_1324710_-	DUF2750 domain-containing protein	NA	NA	NA	NA
WP_005320238.1\|1324804_1325362_-	hypothetical protein	NA	NA	NA	NA
WP_005320240.1\|1325612_1325861_+	TIGR02647 family protein	NA	NA	NA	NA
WP_011898543.1\|1325847_1326153_-	hypothetical protein	NA	NA	NA	NA
WP_005331438.1\|1326257_1326467_-	cold-shock protein	A0A1W6JNX5	Morganella_phage	1.1e-15	60.0
WP_043143953.1\|1326672_1327764_-	2-oxo acid dehydrogenase subunit E2	NA	NA	NA	NA
WP_076611341.1\|1327996_1328914_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_085044777.1\|1329014_1329953_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_005320258.1\|1330094_1331081_-	alpha-ketoacid dehydrogenase subunit beta	A0A0K0KW14	Prochlorococcus_phage	1.8e-07	28.8
WP_159364729.1\|1331183_1332278_-	pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha	NA	NA	NA	NA
WP_005320264.1\|1332552_1333578_-	succinylglutamate desuccinylase	NA	NA	NA	NA
WP_017412738.1\|1333857_1334067_-	DUF1127 domain-containing protein	NA	NA	NA	NA
WP_017412739.1\|1334588_1335482_+	DNA replication terminus site-binding protein	NA	NA	NA	NA
WP_011898541.1\|1335655_1339498_-	DEAD/DEAH box helicase	G8DDA1	Micromonas_pusilla_virus	6.4e-45	30.3
WP_005319007.1\|1339722_1340376_-	DUF480 domain-containing protein	NA	NA	NA	NA
WP_159364730.1\|1340530_1342231_-	ligase	NA	NA	NA	NA
WP_159364981.1\|1342248_1343040_-	exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase	NA	NA	NA	NA
WP_088814108.1\|1343407_1344325_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA

DBSCAN-SWA_8

1652579 : 1723938

Cronobacter_phage(15.38%)

integrase,protease,tRNA,transposase

attL 1664749:1664766|attR 1699129:1699146

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005312386.1\|1652579_1653284_+\|tRNA	tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO	NA	NA	NA	NA
WP_042468298.1\|1653359_1654481_-	beta-ketoacyl-ACP synthase III	NA	NA	NA	NA
WP_042468296.1\|1654538_1655702_-	VWA domain-containing protein	NA	NA	NA	NA
WP_005312374.1\|1655706_1656549_-	MoxR family ATPase	NA	NA	NA	NA
WP_005312371.1\|1656716_1657685_+	cysteine synthase A	A0A1X9I5F1	Streptococcus_phage	1.4e-68	49.8
WP_005303128.1\|1658127_1658385_+	HPr family phosphocarrier protein	NA	NA	NA	NA
WP_159364785.1\|1658429_1660157_+	phosphoenolpyruvate-protein phosphotransferase PtsI	A0A1V0SGR7	Hokovirus	1.4e-15	30.4
WP_159364786.1\|1660200_1660710_+	PTS glucose transporter subunit IIA	NA	NA	NA	NA
WP_005312360.1\|1660798_1661761_-	sensor domain-containing diguanylate cyclase	A0A127AWB9	Bacillus_phage	1.8e-17	33.3
WP_005312357.1\|1661823_1662642_-	hypothetical protein	NA	NA	NA	NA
WP_005312353.1\|1662879_1663428_+	cytochrome b	NA	NA	NA	NA
WP_005312349.1\|1663456_1664107_-	hypothetical protein	NA	NA	NA	NA
WP_159364787.1\|1664284_1668037_-	AAA family ATPase	NA	NA	NA	NA
1664749:1664766	attL	NA	NA	NA	NA
WP_042468655.1\|1668033_1669260_-	exonuclease subunit SbcD	NA	NA	NA	NA
WP_005312341.1\|1669364_1669793_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_005312334.1\|1669972_1670884_+	recombination-associated protein RdgC	A0A1I9KF67	Aeromonas_phage	2.8e-84	51.7
WP_017412621.1\|1673197_1673476_+	transporter	NA	NA	NA	NA
WP_159364788.1\|1673505_1674849_+	cation:proton antiport protein	NA	NA	NA	NA
WP_159364789.1\|1675257_1676439_+	M20/M25/M40 family metallo-hydrolase	NA	NA	NA	NA
WP_005312324.1\|1676516_1676741_-	hypothetical protein	NA	NA	NA	NA
WP_011898977.1\|1677044_1678457_+	pyruvate kinase PykF	NA	NA	NA	NA
WP_159364790.1\|1678604_1681775_+	mechanosensitive ion channel	NA	NA	NA	NA
WP_052521845.1\|1681901_1682582_+\|integrase	integrase arm-type DNA-binding domain-containing protein	A0A1W6JPG6	Morganella_phage	6.0e-47	45.1
WP_076611341.1\|1682655_1683573_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_011898473.1\|1683911_1684103_-	hypothetical protein	NA	NA	NA	NA
WP_155268748.1\|1684212_1684359_-	hypothetical protein	NA	NA	NA	NA
WP_017411356.1\|1684423_1684897_+	transcriptional regulator SlyA	NA	NA	NA	NA
WP_017411357.1\|1684898_1685954_+	HlyD family secretion protein	NA	NA	NA	NA
WP_005316891.1\|1685964_1686993_+	DUF2955 domain-containing protein	NA	NA	NA	NA
WP_005316893.1\|1687148_1687907_+	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_005316896.1\|1688030_1688390_+	hypothetical protein	NA	NA	NA	NA
WP_017411359.1\|1688493_1688664_-	YqaE/Pmp3 family membrane protein	NA	NA	NA	NA
WP_005316900.1\|1688764_1689277_-	anaerobic ribonucleoside-triphosphate reductase-activating protein	K4F9T1	Cronobacter_phage	6.3e-49	57.3
WP_005316902.1\|1689279_1689555_-	hypothetical protein	NA	NA	NA	NA
WP_042468393.1\|1689609_1691727_-	anaerobic ribonucleoside-triphosphate reductase	A0A2I7QNQ7	Vibrio_phage	8.4e-265	64.0
WP_042468392.1\|1692134_1693142_+	sugar ABC transporter ATPase	NA	NA	NA	NA
WP_017411361.1\|1693209_1695216_-	NAD-dependent DNA ligase LigA	A0A289ZTZ3	Serratia_phage	1.2e-138	49.0
WP_017411362.1\|1695316_1696444_-	cell division protein ZipA	NA	NA	NA	NA
WP_159364792.1\|1696459_1699834_-	AAA family ATPase	NA	NA	NA	NA
1699129:1699146	attR	NA	NA	NA	NA
WP_011898471.1\|1699942_1700707_+	sulfate transporter CysZ	NA	NA	NA	NA
WP_005316916.1\|1700847_1701462_+	trimeric intracellular cation channel family protein	NA	NA	NA	NA
WP_005316919.1\|1701558_1701810_-	hypothetical protein	NA	NA	NA	NA
WP_005316921.1\|1701927_1702473_-	DUF882 domain-containing protein	NA	NA	NA	NA
WP_017411363.1\|1702622_1704107_-	L,D-transpeptidase family protein	Q9ZXL6	Pseudomonas_virus	2.5e-05	38.1
WP_159364793.1\|1704187_1704958_-	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_088814343.1\|1705095_1706232_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_042468390.1\|1706569_1707115_+	hypothetical protein	NA	NA	NA	NA
WP_005316928.1\|1707171_1708206_+	glycosyltransferase family 2 protein	A0A192Y8W7	Salmonella_phage	1.0e-82	50.7
WP_005316930.1\|1708202_1708574_+	GtrA family protein	NA	NA	NA	NA
WP_005316932.1\|1708573_1709749_+	hypothetical protein	NA	NA	NA	NA
WP_005316933.1\|1710098_1711298_-\|tRNA	tyrosine--tRNA ligase	NA	NA	NA	NA
WP_005316934.1\|1711408_1712731_+	peptidoglycan DD-metalloendopeptidase family protein	V5R8R0	Arthrobacter_phage	2.8e-16	52.2
WP_005316935.1\|1712979_1714101_+	anhydro-N-acetylmuramic acid kinase	NA	NA	NA	NA
WP_088814343.1\|1714279_1715416_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_076611341.1\|1717249_1718167_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_005316939.1\|1719078_1719354_-	hypothetical protein	NA	NA	NA	NA
WP_005316941.1\|1719850_1721842_-	transketolase	NA	NA	NA	NA
WP_005316943.1\|1722184_1723336_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.2e-129	61.8
WP_005316946.1\|1723404_1723938_+\|protease	SprT family zinc-dependent metalloprotease	A0A060AI19	Cronobacter_phage	6.8e-06	31.0

DBSCAN-SWA_9

2430785 : 2461734

Cafeteria_roenbergensis_virus(25.0%)

protease,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_159364884.1\|2430785_2431703_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_005315988.1\|2432841_2434221_+	ATP-dependent RNA helicase DbpA	E3T5E1	Cafeteria_roenbergensis_virus	1.7e-48	33.1
WP_005315990.1\|2434335_2434626_+	YkgJ family cysteine cluster protein	NA	NA	NA	NA
WP_005315995.1\|2434936_2435335_-	hypothetical protein	NA	NA	NA	NA
WP_088814343.1\|2436737_2437874_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_042468800.1\|2438403_2438622_-	hypothetical protein	NA	NA	NA	NA
WP_085941516.1\|2438732_2439656_-	1,4-dihydroxy-2-naphthoate polyprenyltransferase	NA	NA	NA	NA
WP_017412591.1\|2439846_2441202_+	isochorismate synthase	NA	NA	NA	NA
WP_159364885.1\|2441238_2442957_+	2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase	NA	NA	NA	NA
WP_159364886.1\|2442946_2443705_+	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase	NA	NA	NA	NA
WP_005316007.1\|2443867_2444728_+	1,4-dihydroxy-2-naphthoyl-CoA synthase	NA	NA	NA	NA
WP_005316010.1\|2444727_2445645_+	o-succinylbenzoate synthase	NA	NA	NA	NA
WP_159364887.1\|2445655_2447110_+	AMP-binding protein	A0A1V0SBX8	Catovirus	6.9e-08	29.5
WP_076611341.1\|2447113_2448031_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_005313563.1\|2448199_2448616_+\|tRNA	aminoacyl-tRNA hydrolase	NA	NA	NA	NA
WP_005313565.1\|2448659_2449154_+	methylated-DNA--[protein]-cysteine S-methyltransferase	A0A0G2Y1B6	Acanthamoeba_polyphaga_mimivirus	6.3e-22	51.5
WP_005313567.1\|2449475_2450672_-	NupC/NupG family nucleoside CNT transporter	NA	NA	NA	NA
WP_005313569.1\|2450854_2451811_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_005313573.1\|2451872_2452406_-	glutathione peroxidase	NA	NA	NA	NA
WP_159364889.1\|2452473_2453037_-	hypothetical protein	NA	NA	NA	NA
WP_005313582.1\|2453249_2454383_-	glycerate kinase	W6LM47	Streptococcus_phage	4.9e-46	39.7
WP_159364890.1\|2454392_2455655_-	GntP family permease	NA	NA	NA	NA
WP_005313593.1\|2455774_2456890_-	XRE family transcriptional regulator	NA	NA	NA	NA
WP_005313595.1\|2457098_2457473_+	YacL family protein	NA	NA	NA	NA
WP_005313598.1\|2457523_2457823_+	hypothetical protein	NA	NA	NA	NA
WP_005313601.1\|2457999_2458830_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_076611341.1\|2459417_2460335_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_159364999.1\|2460379_2460709_-	hypothetical protein	NA	NA	NA	NA
WP_076611341.1\|2460816_2461734_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA

DBSCAN-SWA_10

2506063 : 2577250

Tupanvirus(11.76%)

protease,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_076611341.1\|2506063_2506981_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_159368369.1\|2507780_2508410_+	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_088814343.1\|2508488_2509625_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_042468913.1\|2510101_2511238_-	UDP-4-amino-4, 6-dideoxy-N-acetyl-beta-L-altrosamine transaminase	A0A2K9L470	Tupanvirus	2.2e-30	31.1
WP_042468912.1\|2511234_2512239_-	UDP-N-acetylglucosamine 4,6-dehydratase (inverting)	L7RD47	Acanthamoeba_polyphaga_moumouvirus	1.1e-12	28.0
WP_005318307.1\|2512460_2514290_-	maltodextrin glucosidase	NA	NA	NA	NA
WP_005318309.1\|2514296_2515145_-	HDOD domain-containing protein	NA	NA	NA	NA
WP_005318311.1\|2515282_2515702_-	META domain-containing protein	NA	NA	NA	NA
WP_005318313.1\|2515914_2517276_-	molecular chaperone	NA	NA	NA	NA
WP_159364898.1\|2517453_2518443_-	2-hydroxyacid dehydrogenase	M1I636	Acanthocystis_turfacea_Chlorella_virus	3.0e-63	42.9
WP_102665157.1\|2518520_2518982_-	CreA family protein	A0A2I7SAK3	Vibrio_phage	1.3e-13	36.2
WP_005318320.1\|2519156_2520011_-	hypothetical protein	NA	NA	NA	NA
WP_005318322.1\|2520061_2520448_-	DnaK suppressor protein	NA	NA	NA	NA
WP_005318324.1\|2520937_2522269_+	glutamine synthetase	NA	NA	NA	NA
WP_042468411.1\|2522463_2523825_+	aspartate aminotransferase family protein	NA	NA	NA	NA
WP_011898245.1\|2523879_2524977_+	polyamine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_011898246.1\|2525092_2526178_+	polyamine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_042468409.1\|2526254_2527409_+	polyamine ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.5e-26	35.6
WP_005318334.1\|2527405_2528311_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_005318337.1\|2528307_2529150_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_005318340.1\|2529195_2529900_+	MOSC domain-containing protein	NA	NA	NA	NA
WP_005318344.1\|2530420_2530948_-	hypothetical protein	NA	NA	NA	NA
WP_085941554.1\|2531072_2531528_-	thioesterase family protein	NA	NA	NA	NA
WP_005318348.1\|2531670_2533494_+	ATP-dependent DNA helicase RecQ	A0A1V0SBK0	Catovirus	7.4e-84	37.6
WP_005318352.1\|2533595_2533898_-	c-type cytochrome	NA	NA	NA	NA
WP_005318356.1\|2535441_2535729_+	DUF3630 family protein	NA	NA	NA	NA
WP_005318359.1\|2535899_2536574_+	7-cyano-7-deazaguanine/7-aminomethyl-7- deazaguanine transporter	A0A2I7SAW6	Vibrio_phage	3.5e-63	63.7
WP_005318362.1\|2536845_2537331_-	ribonuclease E activity regulator RraA	NA	NA	NA	NA
WP_159364899.1\|2537476_2539330_+	HAMP domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	1.4e-37	34.4
WP_005318369.1\|2539400_2540825_-	magnesium transporter	NA	NA	NA	NA
WP_005318371.1\|2540975_2542382_-	uroporphyrinogen-III C-methyltransferase	NA	NA	NA	NA
WP_005318373.1\|2542394_2543207_-	nitrite transporter NirC	NA	NA	NA	NA
WP_005318375.1\|2543258_2543576_-	nitrite reductase small subunit NirD	NA	NA	NA	NA
WP_085941392.1\|2543682_2546262_-	nitrite reductase large subunit	NA	NA	NA	NA
WP_042468281.1\|2546519_2547440_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_159364900.1\|2547630_2549025_+	MFS transporter	NA	NA	NA	NA
WP_005318386.1\|2549098_2550427_-	HslU--HslV peptidase ATPase subunit	A0A173GFL6	Erwinia_phage	3.4e-46	28.9
WP_005318389.1\|2550491_2551025_-\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_005318391.1\|2551216_2552044_-	cell division protein	NA	NA	NA	NA
WP_159364901.1\|2552047_2553799_-\|tRNA	arginine--tRNA ligase	A0A1V0SIS8	Klosneuvirus	2.1e-83	35.7
WP_085941393.1\|2554019_2554679_+\|protease	ATP-dependent protease	NA	NA	NA	NA
WP_011898253.1\|2554760_2555381_+	sigma-70 family RNA polymerase sigma factor	A0A0F6TH34	Sinorhizobium_phage	2.3e-05	26.7
WP_005318399.1\|2555373_2556051_+	transcriptional regulator	NA	NA	NA	NA
WP_005318402.1\|2556114_2556930_-	undecaprenyl-diphosphate phosphatase	NA	NA	NA	NA
WP_159364902.1\|2557188_2558151_-	L-glyceraldehyde 3-phosphate reductase	NA	NA	NA	NA
WP_005318405.1\|2558302_2559283_-	galactose-1-epimerase	NA	NA	NA	NA
WP_159364903.1\|2559374_2560523_-	galactokinase	NA	NA	NA	NA
WP_042468290.1\|2560519_2561578_-	UDP-glucose--hexose-1-phosphate uridylyltransferase	NA	NA	NA	NA
WP_159364904.1\|2561661_2562675_-	UDP-glucose 4-epimerase GalE	A0A2K9L1R4	Tupanvirus	1.4e-84	46.8
WP_159364905.1\|2562879_2563830_+	substrate-binding domain-containing protein	NA	NA	NA	NA
WP_042468286.1\|2564048_2567126_+	beta-galactosidase	L0N6M2	Herpes_simplex_virus	0.0e+00	53.1
WP_005318413.1\|2567360_2568347_+	galactose/glucose ABC transporter substrate-binding protein MglB	NA	NA	NA	NA
WP_159364906.1\|2568400_2569921_+	galactose/methyl galactoside ABC transporter ATP-binding protein MglA	F2Y2R6	Organic_Lake_phycodnavirus	1.4e-11	32.2
WP_017412477.1\|2569937_2570948_+	galactose/methyl galactoside ABC transporter permease MglC	NA	NA	NA	NA
WP_159364907.1\|2570999_2572727_+	HAMP domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	3.2e-12	34.2
WP_159364953.1\|2572901_2574116_+\|transposase	IS256-like element ISAs3 family transposase	A0A218MNI5	uncultured_virus	4.3e-48	47.9
WP_005318419.1\|2574664_2575033_-	hypothetical protein	NA	NA	NA	NA
WP_159364908.1\|2575034_2575682_-	AAA family ATPase	Q2A085	Sodalis_phage	1.4e-45	47.5
WP_005318424.1\|2575781_2575958_-	hypothetical protein	NA	NA	NA	NA
WP_088814343.1\|2576113_2577250_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA

DBSCAN-SWA_11

2609306 : 2676414

Bacillus_phage(22.22%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_076611341.1\|2609306_2610224_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_076611341.1\|2611060_2611978_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_005318259.1\|2612815_2613220_-	glyoxalase	NA	NA	NA	NA
WP_005318257.1\|2613209_2613974_-	AAC(3) family N-acetyltransferase	NA	NA	NA	NA
WP_034283961.1\|2613970_2614201_-	acyl carrier protein	NA	NA	NA	NA
WP_005318252.1\|2615743_2616283_-	ATP--cob(I)alamin adenosyltransferase	NA	NA	NA	NA
WP_042467733.1\|2616373_2617516_-	hypothetical protein	NA	NA	NA	NA
WP_005318248.1\|2617688_2618822_+\|tRNA	tRNA (uridine(54)-C5)-methyltransferase TrmA	NA	NA	NA	NA
WP_005318245.1\|2618958_2619666_+	two-component system response regulator RstA	W8CYM9	Bacillus_phage	5.5e-27	30.8
WP_005318243.1\|2619703_2621029_+	two-component system sensor histidine kinase RstB	W8CYF6	Bacillus_phage	1.6e-16	24.6
WP_011898228.1\|2621038_2621266_+	hypothetical protein	NA	NA	NA	NA
WP_017412011.1\|2621345_2622602_-	malate dehydrogenase	NA	NA	NA	NA
WP_087757448.1\|2622781_2624239_-	DUF2867 domain-containing protein	NA	NA	NA	NA
WP_005318234.1\|2624384_2624600_-	50S ribosomal protein L31	NA	NA	NA	NA
WP_042467737.1\|2624747_2626955_+	primosomal protein N'	NA	NA	NA	NA
WP_017412009.1\|2627042_2628158_-	hypothetical protein	NA	NA	NA	NA
WP_005318229.1\|2628210_2628765_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_005318227.1\|2628841_2629294_+	HPP family protein	NA	NA	NA	NA
WP_005318225.1\|2629350_2630457_-	porin OmpA	NA	NA	NA	NA
WP_159364915.1\|2630772_2632293_-	threonine ammonia-lyase, biosynthetic	NA	NA	NA	NA
WP_005318219.1\|2632370_2634212_-	dihydroxy-acid dehydratase	NA	NA	NA	NA
WP_042467742.1\|2634361_2635303_-	branched-chain amino acid transaminase	NA	NA	NA	NA
WP_005318216.1\|2635315_2635606_-	acetolactate synthase 2 small subunit	NA	NA	NA	NA
WP_159364916.1\|2635602_2637399_-	acetolactate synthase 2 catalytic subunit	A0A0P0CRC5	Ostreococcus_lucimarinus_virus	5.8e-57	29.2
WP_011707861.1\|2637485_2637584_-	ilvBEDA operon leader peptide	NA	NA	NA	NA
WP_011898225.1\|2637783_2639298_+	YifB family Mg chelatase-like AAA ATPase	NA	NA	NA	NA
WP_005318207.1\|2640472_2640970_-	DUF523 domain-containing protein	NA	NA	NA	NA
WP_011898224.1\|2640966_2641617_-	NUDIX hydrolase	NA	NA	NA	NA
WP_017412156.1\|2641691_2642327_+	nicotinamidase	NA	NA	NA	NA
WP_017412157.1\|2642416_2643595_+	nicotinate phosphoribosyltransferase	NA	NA	NA	NA
WP_159364917.1\|2643719_2644565_+	putative selenate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_005318196.1\|2644561_2645323_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	2.3e-15	31.4
WP_005318191.1\|2646957_2647566_-	thiol:disulfide interchange protein DsbA/DsbL	NA	NA	NA	NA
WP_017412161.1\|2647943_2648933_-	serine/threonine protein kinase	NA	NA	NA	NA
WP_005318186.1\|2649017_2650469_-	cytochrome c oxidase accessory protein CcoG	NA	NA	NA	NA
WP_005318183.1\|2650665_2650929_-	YihD family protein	NA	NA	NA	NA
WP_085941553.1\|2650959_2652075_-	GGDEF domain-containing protein	NA	NA	NA	NA
WP_005318178.1\|2652198_2652588_-	Cu(I)-responsive transcriptional regulator	NA	NA	NA	NA
WP_159364918.1\|2652588_2655006_-	cadmium-translocating P-type ATPase	A0A218MNH6	uncultured_virus	1.9e-111	37.0
WP_005318174.1\|2655195_2655849_-	orotate phosphoribosyltransferase	NA	NA	NA	NA
WP_159364919.1\|2655924_2656641_-	ribonuclease PH	NA	NA	NA	NA
WP_005318170.1\|2656931_2657795_+	YicC family protein	NA	NA	NA	NA
WP_017412166.1\|2657962_2659027_+	glycosyltransferase family 9 protein	NA	NA	NA	NA
WP_005318164.1\|2659001_2660054_-	lipopolysaccharide heptosyltransferase family protein	NA	NA	NA	NA
WP_159364920.1\|2660050_2660734_-	LPS biosynthesis glycosyltransferase	A0A1V0SJT4	Klosneuvirus	6.9e-11	29.4
WP_005318160.1\|2660730_2661942_-	O-antigen ligase family protein	NA	NA	NA	NA
WP_005318158.1\|2661948_2663709_-	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_076611341.1\|2664120_2665038_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_088814343.1\|2665364_2666501_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_159364976.1\|2666604_2667639_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_005318153.1\|2668523_2669483_-	ADP-glyceromanno-heptose 6-epimerase	A0A2K9L0I7	Tupanvirus	7.0e-17	26.6
WP_005318149.1\|2669629_2670274_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_042467749.1\|2670327_2671518_+	glycine C-acetyltransferase	V5LQ39	Emiliania_huxleyi_virus	1.7e-36	28.7
WP_005318146.1\|2671586_2672615_+	L-threonine 3-dehydrogenase	R9TPW0	Vibrio_phage	2.7e-19	84.6
WP_085941552.1\|2672854_2673268_+	cytochrome c5 family protein	NA	NA	NA	NA
WP_076611341.1\|2675496_2676414_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA

DBSCAN-SWA_12

2680587 : 2743071

Pandoravirus(16.67%)

protease,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005318136.1\|2680587_2681424_-\|tRNA	tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA	S4VW33	Pandoravirus	2.1e-17	34.4
WP_085941541.1\|2687448_2688042_-	menaquinone-dependent protoporphyrinogen IX dehydrogenase	NA	NA	NA	NA
WP_021140667.1\|2687980_2689438_-	potassium uptake protein TrkH	NA	NA	NA	NA
WP_159364921.1\|2689474_2690092_-	YigZ family protein	A0A1X9I5T8	Streptococcus_phage	6.9e-26	38.7
WP_159364922.1\|2690091_2691414_-	Xaa-Pro dipeptidase	NA	NA	NA	NA
WP_159364923.1\|2691603_2693541_+	acetoacetate--CoA ligase	NA	NA	NA	NA
WP_017412571.1\|2693745_2695893_+	fatty acid oxidation complex subunit alpha FadB	NA	NA	NA	NA
WP_005320563.1\|2695914_2697078_+	acetyl-CoA C-acyltransferase FadA	NA	NA	NA	NA
WP_085941542.1\|2697352_2698087_+	response regulator transcription factor	NA	NA	NA	NA
WP_159364924.1\|2698138_2699584_+	HAMP domain-containing protein	NA	NA	NA	NA
WP_005320576.1\|2699719_2700958_+	carbohydrate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_005320579.1\|2701032_2701224_-	hypothetical protein	NA	NA	NA	NA
WP_085941543.1\|2701420_2701669_+	sulfurtransferase TusA	A0A140XB86	Dickeya_phage	2.9e-07	72.2
WP_005320589.1\|2701688_2702036_+	RidA family protein	NA	NA	NA	NA
WP_042468577.1\|2702157_2702814_-	OmpA family lipoprotein	NA	NA	NA	NA
WP_005320595.1\|2703008_2703455_-	DNA-3-methyladenine glycosylase I	NA	NA	NA	NA
WP_005320598.1\|2703676_2704600_+\|tRNA	glycine--tRNA ligase subunit alpha	NA	NA	NA	NA
WP_005320601.1\|2704609_2706679_+\|tRNA	glycine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_076611341.1\|2706814_2707732_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_159364953.1\|2708106_2709321_-\|transposase	IS256-like element ISAs3 family transposase	A0A218MNI5	uncultured_virus	4.3e-48	47.9
WP_088814405.1\|2709386_2710649_-\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_005321603.1\|2710848_2711274_-	chaperonin	NA	NA	NA	NA
WP_034283822.1\|2711470_2712862_+	T3SS effector protein-tyrosine-phosphatase AopH	NA	NA	NA	NA
WP_076611341.1\|2713695_2714613_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_005320605.1\|2715256_2715754_-	AAA family ATPase	NA	NA	NA	NA
WP_005320608.1\|2717034_2717799_+	EAL domain-containing protein	NA	NA	NA	NA
WP_005320617.1\|2719525_2719882_+	molecular chaperone	NA	NA	NA	NA
WP_005320619.1\|2720033_2721260_-	amino acid permease	NA	NA	NA	NA
WP_088814339.1\|2721550_2722768_-	4Fe-4S binding protein	NA	NA	NA	NA
WP_042468882.1\|2722885_2723227_-	DUF1971 domain-containing protein	NA	NA	NA	NA
WP_005320623.1\|2723278_2724445_-	NADH:flavorubredoxin reductase NorW	NA	NA	NA	NA
WP_005320624.1\|2724441_2726007_-	anaerobic nitric oxide reductase flavorubredoxin	NA	NA	NA	NA
WP_005320633.1\|2726178_2727708_+	nitric oxide reductase transcriptional regulator NorR	NA	NA	NA	NA
WP_011899241.1\|2727797_2728505_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_088814343.1\|2728780_2729917_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_159364925.1\|2730074_2731664_+	PTS transporter subunit EIIC	NA	NA	NA	NA
WP_076611341.1\|2732402_2733320_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_005320642.1\|2734137_2735142_-	substrate-binding domain-containing protein	C6ZCU4	Enterobacteria_phage	9.5e-33	33.1
WP_088814406.1\|2735595_2736699_+	branched-chain amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_005320646.1\|2736762_2737689_+	high-affinity branched-chain amino acid ABC transporter permease LivH	NA	NA	NA	NA
WP_005320647.1\|2737685_2738954_+	high-affinity branched-chain amino acid ABC transporter permease LivM	NA	NA	NA	NA
WP_042468107.1\|2738950_2739727_+	ABC transporter ATP-binding protein	A0A285PWH2	Cedratvirus	1.6e-11	26.8
WP_005320652.1\|2740327_2741176_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_017411789.1\|2741154_2741748_-	LysE family translocator	NA	NA	NA	NA
WP_005320656.1\|2741917_2742241_+	thiosulfate sulfurtransferase GlpE	NA	NA	NA	NA
WP_017411790.1\|2742237_2743071_+\|protease	rhomboid family intramembrane serine protease GlpG	NA	NA	NA	NA

DBSCAN-SWA_13

3308766 : 3352261

uncultured_Caudovirales_phage(28.57%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_159364942.1\|3308766_3309294_-\|protease	TIGR02281 family clan AA aspartic protease	NA	NA	NA	NA
WP_005314151.1\|3309386_3309959_+	1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD	A0A076YN96	Rhizobium_phage	3.2e-09	30.4
WP_005314150.1\|3310235_3311000_+	pyruvate dehydrogenase complex transcriptional repressor PdhR	NA	NA	NA	NA
WP_005314149.1\|3311079_3313740_+	pyruvate dehydrogenase (acetyl-transferring), homodimeric type	NA	NA	NA	NA
WP_159364301.1\|3313825_3315682_+	pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase	NA	NA	NA	NA
WP_005314147.1\|3315842_3317270_+	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	2.7e-41	26.9
WP_042468131.1\|3317399_3318356_+	sensor domain-containing diguanylate cyclase	G3MA91	Bacillus_virus	5.0e-15	30.9
WP_005314145.1\|3318352_3318535_-	hypothetical protein	NA	NA	NA	NA
WP_159364302.1\|3318670_3320317_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	3.1e-17	60.2
WP_017411941.1\|3320480_3322391_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	1.0e-19	30.3
WP_005314141.1\|3322649_3324908_+	patatin-like phospholipase domain-containing protein	A0A1V0SFX9	Hokovirus	2.0e-06	27.4
WP_159364303.1\|3325136_3327734_+	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase	NA	NA	NA	NA
WP_088814343.1\|3328836_3329973_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_088814108.1\|3330824_3331742_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_042468135.1\|3332260_3333010_-	3-oxoacyl-ACP reductase FabG	NA	NA	NA	NA
WP_011898295.1\|3333186_3334110_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_159364305.1\|3334181_3335093_-	LysR family transcriptional regulator	Q6JIH3	Burkholderia_virus	1.3e-12	26.3
WP_005314128.1\|3335170_3335788_+	LysE family transporter	NA	NA	NA	NA
WP_159364306.1\|3335905_3337300_+	FAD-binding protein	NA	NA	NA	NA
WP_088814347.1\|3337380_3338499_+	GTP-binding protein	NA	NA	NA	NA
WP_076611341.1\|3340445_3341363_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_005314121.1\|3341636_3342146_-	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
WP_005314120.1\|3342198_3342570_-	dihydroneopterin aldolase	NA	NA	NA	NA
WP_011898298.1\|3342739_3343402_+	glycerol-3-phosphate 1-O-acyltransferase PlsY	NA	NA	NA	NA
WP_005314116.1\|3343996_3344329_-	hypothetical protein	NA	NA	NA	NA
WP_005314114.1\|3344459_3344975_+	ClbS/DfsB family four-helix bundle protein	NA	NA	NA	NA
WP_005314112.1\|3345436_3345655_+	hypothetical protein	NA	NA	NA	NA
WP_005314110.1\|3345667_3346192_+	hypothetical protein	NA	NA	NA	NA
WP_005314108.1\|3346211_3346706_+	hypothetical protein	NA	NA	NA	NA
WP_005314106.1\|3346772_3347219_+	DUF2787 domain-containing protein	NA	NA	NA	NA
WP_076611341.1\|3347683_3348601_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_005314084.1\|3349666_3351010_+	two pore domain potassium channel family protein	NA	NA	NA	NA
WP_159364308.1\|3351343_3352261_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA

DBSCAN-SWA_14

3448746 : 3493683

Bacillus_phage(28.57%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_159364279.1\|3448746_3449664_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_042468899.1\|3450137_3451409_+	membrane protein	NA	NA	NA	NA
WP_005320515.1\|3451497_3452751_-	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	5.8e-48	33.0
WP_159364321.1\|3454026_3455259_+	MFS transporter	NA	NA	NA	NA
WP_005320525.1\|3455278_3455737_-	hypothetical protein	NA	NA	NA	NA
WP_159364322.1\|3455917_3456826_+	DNA-directed RNA polymerase subunit delta	NA	NA	NA	NA
WP_159364323.1\|3456879_3457320_-	hypothetical protein	NA	NA	NA	NA
WP_011899092.1\|3457321_3457654_-	hypothetical protein	NA	NA	NA	NA
WP_005320532.1\|3457758_3458319_-	carbonate dehydratase	NA	NA	NA	NA
WP_088814398.1\|3458585_3459206_+	ribonuclease	NA	NA	NA	NA
WP_017412815.1\|3459278_3459557_+	Pathogenicity locus	NA	NA	NA	NA
WP_159368373.1\|3460782_3461055_-	hypothetical protein	NA	NA	NA	NA
WP_042469009.1\|3466858_3467254_+	NUDIX domain-containing protein	A0A0H4J2U2	Stenotrophomonas_phage	3.2e-08	37.5
WP_088814354.1\|3467311_3468541_-	HAMP domain-containing protein	Q8QKV7	Ectocarpus_siliculosus_virus	3.5e-05	29.6
WP_017412757.1\|3468597_3469278_-	response regulator transcription factor	W8CYM9	Bacillus_phage	3.1e-27	34.4
WP_005318615.1\|3469427_3470582_+	efflux RND transporter periplasmic adaptor subunit	A0A140XAI1	Dickeya_phage	6.8e-35	71.9
WP_157669187.1\|3475036_3475177_-	hypothetical protein	NA	NA	NA	NA
WP_159364324.1\|3475163_3477317_+	AsmA family protein	NA	NA	NA	NA
WP_005318627.1\|3477491_3478031_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_159364325.1\|3478103_3478838_+	SDR family oxidoreductase	A0A0M4JSW6	Mollivirus	4.7e-05	26.9
WP_088814343.1\|3479293_3480430_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_005318633.1\|3481452_3481731_-	hypothetical protein	NA	NA	NA	NA
WP_005318634.1\|3481735_3481939_-	hypothetical protein	NA	NA	NA	NA
WP_159364326.1\|3482319_3482538_-	hypothetical protein	NA	NA	NA	NA
WP_159364327.1\|3482520_3483438_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_088814343.1\|3483972_3485109_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_005318641.1\|3485359_3486139_+	sorbitol-6-phosphate dehydrogenase	W8CYX9	Bacillus_phage	2.2e-05	50.9
WP_076611341.1\|3486197_3487115_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_005318643.1\|3487292_3487649_+	glucitol operon activator	NA	NA	NA	NA
WP_011899087.1\|3487738_3488503_+	DNA-binding transcriptional repressor	NA	NA	NA	NA
WP_088814148.1\|3488737_3491620_-	bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase	NA	NA	NA	NA
WP_005318651.1\|3491862_3492309_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_076611341.1\|3492765_3493683_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA

DBSCAN-SWA_15

3525678 : 3560548

Tupanvirus(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_159364338.1\|3525678_3526815_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_088814343.1\|3528458_3529595_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_076611341.1\|3530668_3531586_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_159364332.1\|3532046_3532484_-	VOC family protein	NA	NA	NA	NA
WP_005318743.1\|3534181_3534778_-	DUF1311 domain-containing protein	NA	NA	NA	NA
WP_017413068.1\|3534884_3535247_-	DUF2061 domain-containing protein	NA	NA	NA	NA
WP_005318747.1\|3535439_3535646_+	hypothetical protein	NA	NA	NA	NA
WP_159364333.1\|3535857_3536742_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_076611341.1\|3536786_3537704_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_159364334.1\|3537868_3538210_-	hypothetical protein	NA	NA	NA	NA
WP_005318756.1\|3539008_3539863_-	23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ	NA	NA	NA	NA
WP_085941653.1\|3539856_3540300_-	DUF2390 domain-containing protein	NA	NA	NA	NA
WP_005318760.1\|3540310_3542221_-	ABC transporter ATP-binding protein	A0A2K9L3Z8	Tupanvirus	3.6e-73	33.0
WP_005318762.1\|3542375_3542786_+	CBS domain-containing protein	NA	NA	NA	NA
WP_005318764.1\|3542864_3543320_-	NfeD family protein	NA	NA	NA	NA
WP_005318765.1\|3543316_3544240_-	SPFH/Band 7/PHB domain protein	NA	NA	NA	NA
WP_005318769.1\|3546020_3546974_+	sulfate adenylyltransferase subunit CysD	NA	NA	NA	NA
WP_005318771.1\|3546985_3548401_+	sulfate adenylyltransferase subunit CysN	A0A1V0SGC3	Hokovirus	4.6e-33	28.5
WP_005318772.1\|3548405_3550130_+	SLC13 family permease	NA	NA	NA	NA
WP_159364335.1\|3550301_3550892_+	adenylyl-sulfate kinase	NA	NA	NA	NA
WP_159364336.1\|3551486_3552503_-	hypothetical protein	NA	NA	NA	NA
WP_076611341.1\|3552527_3553445_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_159364337.1\|3553493_3554096_-	NACHT domain-containing protein	NA	NA	NA	NA
WP_011898961.1\|3554100_3555315_-\|transposase	IS256-like element ISAs3 family transposase	A0A218MNI5	uncultured_virus	4.3e-48	47.9
WP_159364338.1\|3555356_3556493_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_159364339.1\|3556673_3557003_-	hypothetical protein	NA	NA	NA	NA
WP_159364340.1\|3557253_3557577_-	hypothetical protein	NA	NA	NA	NA
WP_076611341.1\|3557653_3558571_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_076611341.1\|3559630_3560548_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA

DBSCAN-SWA_16

3608048 : 3617966

uncultured_Mediterranean_phage(25.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005318886.1\|3608048_3608795_+	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	9.7e-67	52.0
WP_005318888.1\|3608799_3609417_+	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	9.0e-34	46.4
WP_159364944.1\|3609419_3609983_+	DedA family protein	NA	NA	NA	NA
WP_159364349.1\|3609992_3611039_+	peptidoglycan DD-metalloendopeptidase family protein	A0A0A7NU10	Lactobacillus_phage	7.9e-14	41.3
WP_017411567.1\|3611086_3612070_+	RNA polymerase sigma factor RpoS	F4YCU2	Synechococcus_phage	9.9e-35	34.1
WP_005318896.1\|3612155_3613169_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	1.5e-107	58.0
WP_005309452.1\|3613348_3613564_+	30S ribosomal protein S21	NA	NA	NA	NA
WP_159364350.1\|3613579_3614023_+	GatB/YqeY domain-containing protein	A0A292GL36	Xanthomonas_phage	1.7e-26	47.9
WP_005318901.1\|3614111_3615899_+	DNA primase	A0A0K1LMQ9	Caulobacter_phage	3.4e-73	41.1
WP_082187144.1\|3616112_3617966_+	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-34	32.6

DBSCAN-SWA_17

3734530 : 3798909

Streptococcus_phage(25.0%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_042469031.1\|3734530_3735946_+\|tRNA	glutamate--tRNA ligase	NA	NA	NA	NA
WP_159364946.1\|3739724_3742724_+	chitinase	A0A1X9VNM7	Mimivirus	2.6e-25	29.1
WP_159364367.1\|3743019_3744237_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_005317900.1\|3744248_3744884_-	energy transducer TonB	NA	NA	NA	NA
WP_159364368.1\|3744900_3745308_-	biopolymer transporter ExbD	NA	NA	NA	NA
WP_005317894.1\|3745375_3745903_-	MotA/TolQ/ExbB proton channel family protein	NA	NA	NA	NA
WP_159364369.1\|3745913_3747278_-	MotA/TolQ/ExbB proton channel family protein	NA	NA	NA	NA
WP_159364370.1\|3747274_3748039_-	DUF3450 family protein	NA	NA	NA	NA
WP_159364371.1\|3748147_3750754_-	TonB-dependent receptor	A0A0P0I887	Acinetobacter_phage	3.9e-38	27.4
WP_076611341.1\|3752006_3752924_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_017412677.1\|3753600_3754644_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_005317877.1\|3756636_3757695_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	1.5e-07	26.8
WP_159364372.1\|3757691_3758693_+	dipeptide ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.2e-20	29.7
WP_159364373.1\|3758896_3759016_-	hypothetical protein	NA	NA	NA	NA
WP_005317866.1\|3759414_3760866_-	aminoacyl-histidine dipeptidase	NA	NA	NA	NA
WP_005317863.1\|3761456_3761762_+	hypothetical protein	NA	NA	NA	NA
WP_005317860.1\|3761797_3762265_+	xanthine phosphoribosyltransferase	NA	NA	NA	NA
WP_159364374.1\|3762375_3763644_+	esterase FrsA	NA	NA	NA	NA
WP_005317854.1\|3763704_3764097_+	sigma factor-binding protein Crl	NA	NA	NA	NA
WP_011898405.1\|3764323_3765427_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	9.0e-61	41.2
WP_042468553.1\|3765524_3766778_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	2.7e-93	46.5
WP_005317845.1\|3766933_3767569_+	murein L,D-transpeptidase catalytic domain family protein	NA	NA	NA	NA
WP_005317842.1\|3767636_3768065_-	universal stress protein	NA	NA	NA	NA
WP_005317837.1\|3768273_3769020_+	hypothetical protein	NA	NA	NA	NA
WP_005317835.1\|3769104_3769473_+	hypothetical protein	NA	NA	NA	NA
WP_005317834.1\|3769600_3770110_-	RNA methyltransferase	NA	NA	NA	NA
WP_042468555.1\|3770307_3771399_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_076611341.1\|3772228_3773146_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_088814298.1\|3773849_3774785_+	cytochrome-c peroxidase	NA	NA	NA	NA
WP_005317820.1\|3775034_3775790_+	DNA/RNA non-specific endonuclease	X2KR27	Campylobacter_phage	5.1e-23	29.1
WP_005317818.1\|3775827_3776043_-	hypothetical protein	NA	NA	NA	NA
WP_076611341.1\|3777329_3778247_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_159364375.1\|3778295_3778718_-	hypothetical protein	NA	NA	NA	NA
WP_159364376.1\|3778899_3779619_+	beta-ketoacyl synthase	NA	NA	NA	NA
WP_005317806.1\|3779603_3780362_+	1-acyl-sn-glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
WP_085941422.1\|3780358_3780646_+	acyl carrier protein	NA	NA	NA	NA
WP_005317801.1\|3780649_3780898_+	acyl carrier protein	NA	NA	NA	NA
WP_005317798.1\|3780866_3781505_+	hypothetical protein	NA	NA	NA	NA
WP_042468706.1\|3781501_3782872_+	acyl-CoA synthetase	NA	NA	NA	NA
WP_159364377.1\|3782855_3783227_+	hydroxymyristoyl-ACP dehydratase	NA	NA	NA	NA
WP_005317790.1\|3783223_3784927_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_005317787.1\|3784913_3786476_+	aromatic amino acid lyase	A0A1V0S940	Catovirus	6.4e-52	31.8
WP_005317781.1\|3786600_3787026_+	acyl-CoA thioesterase	NA	NA	NA	NA
WP_020379605.1\|3787022_3787637_+	outer membrane lipoprotein carrier protein LolA	NA	NA	NA	NA
WP_005317775.1\|3787687_3790063_+	MMPL family transporter	NA	NA	NA	NA
WP_085941573.1\|3790065_3790623_+	DUF3261 domain-containing protein	NA	NA	NA	NA
WP_159364378.1\|3790619_3791801_+	beta-ketoacyl-ACP synthase	NA	NA	NA	NA
WP_005317766.1\|3791797_3792259_+	hotdog family protein	NA	NA	NA	NA
WP_005317763.1\|3792268_3792994_+	3-oxoacyl-ACP reductase FabG	NA	NA	NA	NA
WP_005317759.1\|3793085_3794312_+	beta-ketoacyl-ACP synthase	NA	NA	NA	NA
WP_011898412.1\|3794402_3794819_+	DUF2541 family protein	NA	NA	NA	NA
WP_005317752.1\|3794855_3795386_-	molybdopterin adenylyltransferase	NA	NA	NA	NA
WP_085044777.1\|3795562_3796501_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_076611341.1\|3796601_3797519_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_088814343.1\|3797772_3798909_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA

DBSCAN-SWA_18

3877211 : 3917905

Micromonas_pusilla_virus(25.0%)

protease,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005317541.1\|3877211_3879161_+\|protease	ATP-dependent zinc metalloprotease FtsH	M4QMW8	Micromonas_pusilla_virus	4.9e-118	41.8
WP_005317538.1\|3879223_3880069_+	dihydropteroate synthase	A0A0B5J4J5	Pandoravirus	2.5e-18	27.9
WP_159364394.1\|3880086_3881421_+	phosphoglucosamine mutase	NA	NA	NA	NA
WP_159364395.1\|3881551_3882316_+	triose-phosphate isomerase	NA	NA	NA	NA
WP_005317530.1\|3882316_3882643_+	preprotein translocase subunit SecG	NA	NA	NA	NA
WP_005317527.1\|3883072_3883531_+	ribosome maturation factor RimP	NA	NA	NA	NA
WP_005317524.1\|3883545_3885048_+	transcription termination/antitermination protein NusA	NA	NA	NA	NA
WP_042467425.1\|3885068_3887765_+	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	4.8e-23	24.4
WP_005317518.1\|3887820_3888255_+	30S ribosome-binding factor RbfA	NA	NA	NA	NA
WP_005317516.1\|3888256_3889216_+\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
WP_005317514.1\|3889360_3889630_+	30S ribosomal protein S15	NA	NA	NA	NA
WP_159364396.1\|3889797_3891939_+	polyribonucleotide nucleotidyltransferase	NA	NA	NA	NA
WP_042467430.1\|3892070_3893291_+	MFS transporter	NA	NA	NA	NA
WP_005317508.1\|3893287_3894370_-	diguanylate cyclase	NA	NA	NA	NA
WP_005317505.1\|3894507_3894861_-	hypothetical protein	NA	NA	NA	NA
WP_085941575.1\|3895038_3895413_+	DUF1090 domain-containing protein	NA	NA	NA	NA
WP_076611341.1\|3897099_3898017_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_159364397.1\|3898039_3898810_-	dipeptidase PepE	NA	NA	NA	NA
WP_085941423.1\|3899039_3900425_-	endonuclease/exonuclease/phosphatase family protein	NA	NA	NA	NA
WP_051163830.1\|3900547_3901318_+	patatin family protein	NA	NA	NA	NA
WP_076611341.1\|3901391_3902309_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_005317473.1\|3903010_3903985_+	L-tyrosine/L-tryptophan isonitrile synthase family protein	NA	NA	NA	NA
WP_076611341.1\|3904105_3905023_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_159364947.1\|3905090_3905942_+	TauD/TfdA family dioxygenase	NA	NA	NA	NA
WP_005317468.1\|3905941_3907225_+	N-glycosyltransferase	NA	NA	NA	NA
WP_042468717.1\|3907490_3908411_+	L,D-transpeptidase family protein	NA	NA	NA	NA
WP_011898434.1\|3908494_3908812_-	hypothetical protein	NA	NA	NA	NA
WP_005317460.1\|3909017_3910358_-	TldD/PmbA family protein	NA	NA	NA	NA
WP_159364399.1\|3910357_3911752_-	TldD/PmbA family protein	NA	NA	NA	NA
WP_005317454.1\|3911948_3912467_-	flavodoxin FldB	NA	NA	NA	NA
WP_011898435.1\|3912672_3913584_+	site-specific tyrosine recombinase XerD	A0A0K2CP59	Brevibacillus_phage	8.3e-28	29.6
WP_076611341.1\|3913786_3914704_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_159364401.1\|3916272_3916626_-	large-conductance mechanosensitive channel protein MscL	NA	NA	NA	NA
WP_088814343.1\|3916768_3917905_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA

DBSCAN-SWA_19

3923632 : 3976100

Stx2-converting_phage(20.0%)

protease,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_159364402.1\|3923632_3924283_+\|transposase	heteromeric transposase endonuclease subunit TnsA	NA	NA	NA	NA
WP_076611341.1\|3925104_3926022_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_159364404.1\|3927227_3928124_+	AAA family ATPase	NA	NA	NA	NA
WP_159364405.1\|3928123_3929128_+	hypothetical protein	NA	NA	NA	NA
WP_159368376.1\|3929510_3930155_-	hypothetical protein	NA	NA	NA	NA
WP_159364407.1\|3930251_3931250_-	hypothetical protein	NA	NA	NA	NA
WP_076611341.1\|3931344_3932262_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_076611341.1\|3932707_3933625_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_159368377.1\|3933647_3934049_-	hypothetical protein	NA	NA	NA	NA
WP_159368378.1\|3934052_3934895_-	hypothetical protein	NA	NA	NA	NA
WP_088814343.1\|3934962_3936099_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_159364411.1\|3936177_3937131_-	hypothetical protein	NA	NA	NA	NA
WP_159364412.1\|3938107_3939196_-	hypothetical protein	NA	NA	NA	NA
WP_159364413.1\|3939714_3941400_-	hypothetical protein	NA	NA	NA	NA
WP_042467797.1\|3941495_3942476_-	lipoyl synthase	NA	NA	NA	NA
WP_042467798.1\|3942561_3943239_-	lipoyl(octanoyl) transferase LipB	NA	NA	NA	NA
WP_005317360.1\|3943320_3943584_-	YbeD family protein	NA	NA	NA	NA
WP_159364414.1\|3943863_3945054_-	D-alanyl-D-alanine carboxypeptidase	B6DZZ7	Stx2-converting_phage	6.5e-81	42.0
WP_011898443.1\|3945249_3946200_-	septal ring lytic transglycosylase RlpA family protein	NA	NA	NA	NA
WP_042467799.1\|3946141_3947140_-	lytic murein transglycosylase B	NA	NA	NA	NA
WP_005317349.1\|3947139_3948243_-	rod shape-determining protein RodA	NA	NA	NA	NA
WP_005317346.1\|3948235_3950152_-	penicillin-binding protein 2	NA	NA	NA	NA
WP_017411988.1\|3950199_3950667_-	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	NA	NA	NA	NA
WP_005317340.1\|3950686_3951028_-	ribosome silencing factor	NA	NA	NA	NA
WP_005317337.1\|3951213_3951858_-	nicotinate-nucleotide adenylyltransferase	NA	NA	NA	NA
WP_005317335.1\|3951934_3952966_-	DNA polymerase III subunit delta	NA	NA	NA	NA
WP_005317332.1\|3952965_3953112_-	hypothetical protein	NA	NA	NA	NA
WP_005317329.1\|3953125_3953608_-	hypothetical protein	NA	NA	NA	NA
WP_005317327.1\|3953774_3956351_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	5.9e-188	42.3
WP_005317324.1\|3956496_3957003_+	zinc ribbon-containing protein	NA	NA	NA	NA
WP_042467801.1\|3957089_3958634_-	apolipoprotein N-acyltransferase	NA	NA	NA	NA
WP_005317320.1\|3958912_3959797_-	CNNM family magnesium/cobalt transport protein CorC	NA	NA	NA	NA
WP_005317318.1\|3959892_3960357_-	rRNA maturation RNase YbeY	NA	NA	NA	NA
WP_005317316.1\|3960353_3961397_-	PhoH family protein	A0A0S0MVD6	Pseudomonas_phage	2.4e-47	44.6
WP_005317314.1\|3961453_3962887_-\|tRNA	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	NA	NA	NA	NA
WP_005317312.1\|3963154_3964318_+	NAD(P)-binding protein	NA	NA	NA	NA
WP_042467803.1\|3964493_3965153_+	cold shock domain-containing protein	NA	NA	NA	NA
WP_005317308.1\|3965356_3966313_+	sensor domain-containing diguanylate cyclase	NA	NA	NA	NA
WP_005317306.1\|3966298_3967261_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_005317304.1\|3967376_3967601_+	hypothetical protein	NA	NA	NA	NA
WP_005317302.1\|3967597_3968251_+	HAD-IA family hydrolase	NA	NA	NA	NA
WP_005317295.1\|3968313_3968916_-	nitroreductase family protein	NA	NA	NA	NA
WP_005317292.1\|3969144_3969564_+	hypothetical protein	NA	NA	NA	NA
WP_005317289.1\|3969798_3970191_+	hypothetical protein	NA	NA	NA	NA
WP_005317286.1\|3970261_3971218_-	D-2-hydroxyacid dehydrogenase	M1HUT5	Acanthocystis_turfacea_Chlorella_virus	3.1e-25	27.9
WP_159364415.1\|3971345_3972098_-	DUF3530 family protein	NA	NA	NA	NA
WP_005317282.1\|3972217_3972784_-	elongation factor P	NA	NA	NA	NA
WP_042467805.1\|3972829_3974017_-	elongation factor P maturation arginine rhamnosyltransferase EarP	NA	NA	NA	NA
WP_042467807.1\|3974149_3975193_-	GMP reductase	A0A0N9Q9A5	Chrysochromulina_ericina_virus	5.9e-102	55.7
WP_005317263.1\|3975596_3976100_+\|protease	ATP-dependent zinc protease	NA	NA	NA	NA

DBSCAN-SWA_20

3997563 : 4065288

Synechococcus_phage(16.67%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011899080.1\|3997563_3998595_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_159364421.1\|3998658_4000089_+	MATE family efflux transporter	NA	NA	NA	NA
WP_159364422.1\|4000185_4001010_-	peptidoglycan DD-metalloendopeptidase family protein	A0A292GJG6	Xanthomonas_phage	3.1e-13	31.9
WP_005317152.1\|4001057_4001912_-	hypothetical protein	NA	NA	NA	NA
WP_017413017.1\|4002088_4002865_+	hypothetical protein	NA	NA	NA	NA
WP_005317141.1\|4002932_4003832_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_005317139.1\|4003960_4004821_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_005317138.1\|4004903_4005539_+	DsbA family protein	NA	NA	NA	NA
WP_159364423.1\|4005764_4007393_+	HAMP domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	2.7e-21	33.0
WP_159364948.1\|4007428_4008451_+	DNA-binding transcriptional regulator OxyR	NA	NA	NA	NA
WP_159364424.1\|4008512_4010999_-	PBP1A family penicillin-binding protein	NA	NA	NA	NA
WP_088814290.1\|4011284_4012358_+	type IV pilus assembly protein PilM	NA	NA	NA	NA
WP_011898454.1\|4013516_4014047_+	pilus assembly protein PilP	NA	NA	NA	NA
WP_042468062.1\|4016447_4016966_+	shikimate kinase AroK	NA	NA	NA	NA
WP_159364425.1\|4016980_4018060_+	3-dehydroquinate synthase	NA	NA	NA	NA
WP_159364426.1\|4018052_4019648_+	cell division protein DamX	NA	NA	NA	NA
WP_017412038.1\|4019718_4020591_+	Dam family site-specific DNA-(adenine-N6)-methyltransferase	A0A1S6L1V5	Vibrio_phage	5.5e-69	50.0
WP_005317108.1\|4020907_4021582_+	ribulose-phosphate 3-epimerase	NA	NA	NA	NA
WP_005317106.1\|4021568_4022237_+	phosphoglycolate phosphatase	A0A1D8KNV9	Synechococcus_phage	5.6e-05	28.4
WP_005317104.1\|4022275_4023280_+\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_005317103.1\|4023403_4023619_+	hypothetical protein	NA	NA	NA	NA
WP_005317102.1\|4023640_4024222_+	aminodeoxychorismate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	1.7e-71	63.7
WP_005317101.1\|4024499_4025717_+	aspartate aminotransferase family protein	A0A1V0SKB7	Klosneuvirus	2.6e-24	27.1
WP_005317100.1\|4025792_4026812_+	arginine N-succinyltransferase	NA	NA	NA	NA
WP_159364427.1\|4026896_4028366_+	succinylglutamate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_005317093.1\|4028496_4029294_+	DUF1338 domain-containing protein	NA	NA	NA	NA
WP_159364428.1\|4029471_4030044_-	beta-phosphoglucomutase family hydrolase	A0A1D8KPI1	Synechococcus_phage	4.0e-12	27.7
WP_159364429.1\|4030230_4031595_+	MFS transporter	NA	NA	NA	NA
WP_076611341.1\|4035661_4036579_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_005311784.1\|4036876_4038223_+	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	2.6e-78	38.6
WP_005311785.1\|4038726_4038969_-	YheU family protein	NA	NA	NA	NA
WP_088814108.1\|4039641_4040559_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_005311789.1\|4041262_4042246_-	hydrolase	NA	NA	NA	NA
WP_005311791.1\|4042317_4043217_-	chemotaxis protein CheV	NA	NA	NA	NA
WP_005311793.1\|4043399_4044086_-	hypothetical protein	NA	NA	NA	NA
WP_011899030.1\|4044125_4044332_+	YheV family putative metal-binding protein	NA	NA	NA	NA
WP_021138314.1\|4044486_4045122_+	peptidylprolyl isomerase	NA	NA	NA	NA
WP_005311800.1\|4045196_4045412_-	SlyX family protein	NA	NA	NA	NA
WP_159364432.1\|4045426_4046395_-	PQQ-binding-like beta-propeller repeat protein	NA	NA	NA	NA
WP_011899028.1\|4046514_4047321_+	FKBP-type peptidyl-prolyl cis-trans isomerase	NA	NA	NA	NA
WP_159364433.1\|4047473_4048880_+	response regulator	NA	NA	NA	NA
WP_005311807.1\|4048904_4049774_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_017412614.1\|4049887_4050223_-	hypothetical protein	NA	NA	NA	NA
WP_005311811.1\|4050330_4050669_-	DUF2956 domain-containing protein	NA	NA	NA	NA
WP_005311813.1\|4050755_4052594_-	bifunctional metallophosphatase/5'-nucleotidase	NA	NA	NA	NA
WP_017412914.1\|4052819_4054385_-	EAL domain-containing protein	NA	NA	NA	NA
WP_042468443.1\|4054583_4055438_-	Tim44 domain-containing protein	NA	NA	NA	NA
WP_005311820.1\|4055623_4055725_+	hypothetical protein	NA	NA	NA	NA
WP_159364434.1\|4055875_4057270_+	replicative DNA helicase	A0A1B0VG30	Salmonella_phage	1.8e-178	70.8
WP_085941643.1\|4057370_4057445_+	hypothetical protein	NA	NA	NA	NA
WP_005311825.1\|4057618_4058692_+	alanine racemase	A0A0P0YM39	Yellowstone_lake_mimivirus	4.3e-23	27.2
WP_005311827.1\|4058759_4059008_-	YfhL family 4Fe-4S dicluster ferredoxin	A0A1B1IWY9	uncultured_Mediterranean_phage	3.0e-20	55.3
WP_005311829.1\|4059009_4060371_-\|tRNA	tRNA 5-hydroxyuridine modification protein YegQ	Q6DW11	Phage_TP	1.7e-165	76.2
WP_159364949.1\|4060610_4061315_-	EAL domain-containing protein	NA	NA	NA	NA
WP_088814343.1\|4061418_4062555_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_159364435.1\|4062868_4063102_+	hypothetical protein	NA	NA	NA	NA
WP_076611341.1\|4063017_4063935_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_088814343.1\|4064151_4065288_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA

DBSCAN-SWA_21

4328281 : 4378521

uncultured_Caudovirales_phage(33.33%)

protease,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_159364484.1\|4328281_4329199_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_159364485.1\|4329837_4330755_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_042468377.1\|4330877_4332086_-	sodium:proton antiporter	NA	NA	NA	NA
WP_159364486.1\|4332118_4333270_-	hyaluronidase	NA	NA	NA	NA
WP_005312960.1\|4333311_4335039_-	potassium/proton antiporter	NA	NA	NA	NA
WP_017411705.1\|4335318_4335465_-	hypothetical protein	NA	NA	NA	NA
WP_005312966.1\|4335461_4336151_-	M15 family metallopeptidase	NA	NA	NA	NA
WP_005312969.1\|4336147_4337275_-	succinyl-diaminopimelate desuccinylase	NA	NA	NA	NA
WP_005312972.1\|4337294_4337645_-	ArsC family reductase	NA	NA	NA	NA
WP_042468381.1\|4337861_4338773_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_011898931.1\|4339088_4339460_-	hypothetical protein	NA	NA	NA	NA
WP_005312985.1\|4339762_4340419_-	diphthine--ammonia ligase	NA	NA	NA	NA
WP_017411707.1\|4340580_4341924_-	anaerobic C4-dicarboxylate transporter	NA	NA	NA	NA
WP_159364487.1\|4342291_4343692_-\|tRNA	asparagine--tRNA ligase	A0A167RLM0	Powai_lake_megavirus	2.9e-80	37.2
WP_005312993.1\|4343862_4344237_+	hypothetical protein	NA	NA	NA	NA
WP_159364488.1\|4344233_4345046_-	HAMP domain-containing protein	NA	NA	NA	NA
WP_159364489.1\|4345181_4346456_-	adenosylmethionine--8-amino-7-oxononanoate transaminase	A0A1V0SKB7	Klosneuvirus	3.5e-16	30.0
WP_005313000.1\|4346648_4347737_+	biotin synthase BioB	NA	NA	NA	NA
WP_042468382.1\|4347733_4348930_+	8-amino-7-oxononanoate synthase	NA	NA	NA	NA
WP_085941631.1\|4348919_4349735_+	malonyl-ACP O-methyltransferase BioC	NA	NA	NA	NA
WP_005313009.1\|4349878_4350559_+	ATP-dependent dethiobiotin synthetase BioD	NA	NA	NA	NA
WP_005313012.1\|4350673_4351546_+\|protease	protease HtpX	NA	NA	NA	NA
WP_159364490.1\|4351622_4353335_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	2.0e-14	55.8
WP_042468387.1\|4353545_4355354_-	MOSC domain-containing protein	A0A222YX16	Synechococcus_phage	5.0e-08	40.8
WP_159364491.1\|4355706_4357353_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_076611341.1\|4359879_4360797_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_005313020.1\|4362176_4362392_-	DUF465 domain-containing protein	NA	NA	NA	NA
WP_005313022.1\|4362677_4363268_-	hypothetical protein	NA	NA	NA	NA
WP_159364493.1\|4363279_4364626_-	MATE family efflux transporter	NA	NA	NA	NA
WP_159364494.1\|4364761_4366585_-	STAS domain-containing protein	A0A2H4J153	uncultured_Caudovirales_phage	2.0e-17	27.4
WP_005313033.1\|4366655_4367249_-	nucleotidyltransferase family protein	NA	NA	NA	NA
WP_005313036.1\|4367238_4367496_-	N-acetyltransferase	NA	NA	NA	NA
WP_017411716.1\|4367630_4368545_+	cysteine synthase CysM	A0A1X9I5K7	Streptococcus_phage	2.3e-49	39.5
WP_005313042.1\|4368713_4368995_+	hypothetical protein	NA	NA	NA	NA
WP_159364495.1\|4369029_4370214_-	iron-containing alcohol dehydrogenase	NA	NA	NA	NA
WP_005313047.1\|4370231_4370750_-	hypothetical protein	NA	NA	NA	NA
WP_005313049.1\|4370730_4371333_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_159364496.1\|4371353_4372787_-	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_005313055.1\|4373000_4373294_+	hypothetical protein	NA	NA	NA	NA
WP_159364954.1\|4373363_4373675_-	protein NlpC	NA	NA	NA	NA
WP_076611341.1\|4373780_4374698_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_005313062.1\|4376465_4377374_-	hydrogen peroxide-inducible genes activator	NA	NA	NA	NA
WP_159364497.1\|4377489_4378521_-\|transposase	IS630 family transposase	NA	NA	NA	NA

DBSCAN-SWA_22

4403714 : 4458820

Bodo_saltans_virus(16.67%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_076611341.1\|4403714_4404632_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_076611341.1\|4405062_4405980_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_005319184.1\|4406589_4407720_-	cupin domain-containing protein	NA	NA	NA	NA
WP_017412873.1\|4407896_4409267_-	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	1.1e-111	47.3
WP_042468762.1\|4409442_4410054_-	high frequency lysogenization protein HflD	NA	NA	NA	NA
WP_005319178.1\|4410251_4411358_-\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_011898520.1\|4411676_4412138_-	NUDIX hydrolase	A0A023W5N2	Serratia_phage	8.5e-05	62.2
WP_088814280.1\|4412152_4413127_-	pseudouridine synthase	NA	NA	NA	NA
WP_005319170.1\|4413197_4413965_-	PTS transporter subunit EIIA	NA	NA	NA	NA
WP_005319168.1\|4413965_4414271_-	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_005319166.1\|4414484_4415891_-	hexose-6-phosphate:phosphate antiporter	NA	NA	NA	NA
WP_159364506.1\|4417500_4418418_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_011898521.1\|4418873_4419626_+	phosphotransferase	NA	NA	NA	NA
WP_076611341.1\|4421013_4421931_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_005314572.1\|4422493_4422802_+	hypothetical protein	NA	NA	NA	NA
WP_034282846.1\|4424725_4425472_-	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_017412979.1\|4425587_4426334_-	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_005314576.1\|4426407_4426911_-	GDYXXLXY domain-containing protein	NA	NA	NA	NA
WP_005314577.1\|4426907_4427915_-	DUF4401 domain-containing protein	NA	NA	NA	NA
WP_005314579.1\|4429143_4429701_-	TMEM165/GDT1 family protein	NA	NA	NA	NA
WP_085941442.1\|4429945_4430320_-	stress response translation initiation inhibitor YciH	NA	NA	NA	NA
WP_005314583.1\|4430394_4430622_+	ferrous iron transport protein A	NA	NA	NA	NA
WP_159364507.1\|4430618_4432889_+	Fe(2+) transporter permease subunit FeoB	NA	NA	NA	NA
WP_017412111.1\|4432885_4433128_+	LuxR family transcriptional regulator	NA	NA	NA	NA
WP_076611341.1\|4433384_4434302_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_159364955.1\|4434324_4434786_-	cupin fold metalloprotein, WbuC family	NA	NA	NA	NA
WP_017412109.1\|4434919_4436191_-	glucose-1-phosphate adenylyltransferase	NA	NA	NA	NA
WP_159364508.1\|4436464_4437610_-	PilT/PilU family type 4a pilus ATPase	NA	NA	NA	NA
WP_005314602.1\|4437669_4438026_-	DMT family protein	NA	NA	NA	NA
WP_005314604.1\|4438137_4438869_+	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_005314605.1\|4438972_4439980_+	vitamin B12 ABC transporter permease BtuC	NA	NA	NA	NA
WP_034282866.1\|4440078_4440849_+	ATP-binding cassette domain-containing protein	A0A1M7XV31	Cedratvirus	6.0e-11	30.3
WP_017412107.1\|4440965_4442027_-	3-deoxy-7-phosphoheptulonate synthase	S4VUY9	Pandoravirus	9.2e-87	50.0
WP_005314618.1\|4442181_4442562_+	diacylglycerol kinase	NA	NA	NA	NA
WP_005314621.1\|4442746_4443979_-	phosphoglycerate dehydrogenase	A0A1V0SBV6	Catovirus	6.9e-110	48.9
WP_005314623.1\|4444207_4444861_-	ribose-5-phosphate isomerase RpiA	NA	NA	NA	NA
WP_005314624.1\|4445116_4445725_-	5-formyltetrahydrofolate cyclo-ligase	NA	NA	NA	NA
WP_005314627.1\|4445879_4447214_-	Na+/H+ antiporter NhaC family protein	NA	NA	NA	NA
WP_017412106.1\|4447624_4448593_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_005314633.1\|4448840_4449653_+	4-hydroxy-tetrahydrodipicolinate reductase	NA	NA	NA	NA
WP_005314635.1\|4450330_4451482_+	glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit	R4TGJ8	Halovirus	1.4e-48	32.9
WP_017412104.1\|4451498_4454723_+	carbamoyl-phosphate synthase large subunit	NA	NA	NA	NA
WP_005314639.1\|4455255_4456914_+	2-isopropylmalate synthase	NA	NA	NA	NA
WP_159364279.1\|4457902_4458820_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA

DBSCAN-SWA_23

4468789 : 4534672

Vibrio_phage(25.0%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_087757302.1\|4468789_4469221_+\|protease	protease	NA	NA	NA	NA
WP_076611341.1\|4470344_4471262_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_005314672.1\|4471437_4471917_+	redox-sensitive transcriptional activator SoxR	NA	NA	NA	NA
WP_005314674.1\|4471979_4472567_+	methyltransferase	NA	NA	NA	NA
WP_159364510.1\|4472569_4472980_+	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_159364511.1\|4473073_4474489_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_005314684.1\|4474501_4478959_-	glutamate synthase large subunit	NA	NA	NA	NA
WP_005314700.1\|4479559_4480495_+	TIGR01212 family radical SAM protein	NA	NA	NA	NA
WP_005314720.1\|4480912_4483057_+	type I secretion system permease/ATPase	F2Y2R6	Organic_Lake_phycodnavirus	6.3e-26	33.9
WP_017412894.1\|4483049_4484468_+	HlyD family type I secretion periplasmic adaptor subunit	NA	NA	NA	NA
WP_005314727.1\|4484503_4485829_+	TolC family outer membrane protein	NA	NA	NA	NA
WP_005314730.1\|4485950_4486712_+	hypothetical protein	NA	NA	NA	NA
WP_005314739.1\|4486715_4488641_+	EAL domain-containing protein	NA	NA	NA	NA
WP_159368383.1\|4488900_4494591_+	retention module-containing protein	NA	NA	NA	NA
WP_042468729.1\|4494677_4495235_+	hypothetical protein	NA	NA	NA	NA
WP_088814343.1\|4495357_4496494_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_159364957.1\|4496597_4497263_+	SIMPL domain-containing protein	NA	NA	NA	NA
WP_159364958.1\|4497373_4498530_-\|transposase	IS3 family transposase	Q716C2	Shigella_phage	5.2e-83	50.2
WP_076611341.1\|4498554_4499472_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_102665338.1\|4499716_4500724_+	hypothetical protein	NA	NA	NA	NA
WP_005314771.1\|4503133_4503313_-	hypothetical protein	NA	NA	NA	NA
WP_042468640.1\|4503666_4504860_+	trans-2-enoyl-CoA reductase family protein	NA	NA	NA	NA
WP_159364512.1\|4505022_4506498_+	YfcC family protein	NA	NA	NA	NA
WP_005314787.1\|4508159_4508372_+	DUF1653 domain-containing protein	NA	NA	NA	NA
WP_159364513.1\|4508433_4508697_-	GrxA family glutaredoxin	A0A2I7SAE2	Vibrio_phage	5.2e-23	61.5
WP_042468643.1\|4508894_4510340_-	D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase	NA	NA	NA	NA
WP_042468644.1\|4510445_4512206_-	DEAD/DEAH box helicase	M4Q3N1	Vibrio_phage	1.9e-92	40.9
WP_005314797.1\|4512307_4513345_-	HlyD family secretion protein	NA	NA	NA	NA
WP_005314799.1\|4513348_4513687_-	DUF3302 domain-containing protein	NA	NA	NA	NA
WP_159364514.1\|4513975_4515397_-	carbon starvation protein A	NA	NA	NA	NA
WP_159364515.1\|4515539_4516244_-	two-component system response regulator BtsR	NA	NA	NA	NA
WP_005314809.1\|4516319_4517996_-	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	8.4e-159	55.9
WP_076611341.1\|4518600_4519518_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_005314815.1\|4520766_4523442_-	bifunctional acetaldehyde-CoA/alcohol dehydrogenase	NA	NA	NA	NA
WP_085941443.1\|4523737_4524466_-	2OG-Fe dioxygenase family protein	NA	NA	NA	NA
WP_005314822.1\|4524638_4525274_+	YchE family NAAT transporter	NA	NA	NA	NA
WP_042468196.1\|4525556_4527176_+	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_021139963.1\|4527274_4528195_+	oligopeptide ABC transporter permease OppB	NA	NA	NA	NA
WP_159364516.1\|4528209_4529121_+	oligopeptide ABC transporter permease OppC	NA	NA	NA	NA
WP_005314832.1\|4529153_4530140_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.4e-15	31.7
WP_005314835.1\|4530136_4530250_+	hypothetical protein	NA	NA	NA	NA
WP_042468189.1\|4530250_4531246_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.2e-19	31.9
WP_034282953.1\|4531548_4532493_+	TerC family protein	A0A291LBC5	Escherichia_phage	9.2e-38	36.3
WP_076611341.1\|4533754_4534672_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA

DBSCAN-SWA_24

4552794 : 4608922

Klosneuvirus(30.0%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_076611341.1\|4552794_4553712_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_017411553.1\|4555258_4555663_-	NADH-quinone oxidoreductase subunit A	NA	NA	NA	NA
WP_159364521.1\|4555989_4556865_-	OmpA family protein	NA	NA	NA	NA
WP_005314938.1\|4558087_4558705_-	membrane protein	NA	NA	NA	NA
WP_005314942.1\|4558725_4559460_-	TPM domain-containing protein	NA	NA	NA	NA
WP_011898627.1\|4559456_4560047_-	LemA family protein	A0A1X9IGG1	Lactococcus_phage	1.1e-15	34.5
WP_005314948.1\|4560104_4560842_-	penicillin-insensitive murein endopeptidase	NA	NA	NA	NA
WP_011898628.1\|4560841_4561744_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_017411549.1\|4561716_4562538_-	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_017411548.1\|4562540_4563338_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_076611341.1\|4563893_4564811_+\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_159364959.1\|4564814_4565702_-	TonB family protein	NA	NA	NA	NA
WP_159364522.1\|4566359_4567277_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA
WP_017412971.1\|4567474_4568938_+	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	5.3e-93	39.6
WP_005315336.1\|4569021_4570602_+	glutamine-hydrolyzing GMP synthase	NA	NA	NA	NA
WP_088814221.1\|4571015_4571255_+	hypothetical protein	NA	NA	NA	NA
WP_159364523.1\|4572241_4572895_+	hypothetical protein	NA	NA	NA	NA
WP_088814343.1\|4572903_4574040_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_159368384.1\|4574153_4574318_+	hypothetical protein	NA	NA	NA	NA
WP_005315340.1\|4574622_4575996_+	protein kinase	NA	NA	NA	NA
WP_042467896.1\|4576219_4576867_+	thiopurine S-methyltransferase	NA	NA	NA	NA
WP_159364524.1\|4577170_4579945_-	insulinase family protein	A0A1V0SJA4	Klosneuvirus	6.8e-89	27.0
WP_017411860.1\|4580107_4580575_+	phosphohistidine phosphatase SixA	NA	NA	NA	NA
WP_005315346.1\|4580708_4580915_+	DUF1107 domain-containing protein	NA	NA	NA	NA
WP_005315348.1\|4581115_4582036_+	DMT family transporter	NA	NA	NA	NA
WP_042467895.1\|4582083_4583700_-	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_005315352.1\|4584083_4585118_+	class 1 fructose-bisphosphatase	A0A1V0SKX4	Klosneuvirus	4.2e-76	46.5
WP_159364525.1\|4585206_4588671_-	transcription-repair coupling factor	NA	NA	NA	NA
WP_005315356.1\|4588680_4589256_-	PilZ domain-containing protein	NA	NA	NA	NA
WP_005315358.1\|4589332_4590568_+	lipoprotein-releasing ABC transporter permease subunit	NA	NA	NA	NA
WP_087755599.1\|4590560_4591322_+	lipoprotein-releasing ABC transporter ATP-binding protein LolD	G9BWD6	Planktothrix_phage	2.0e-35	42.1
WP_005315361.1\|4591321_4592563_+	lipoprotein-releasing ABC transporter permease subunit LolE	NA	NA	NA	NA
WP_011898663.1\|4593339_4593774_-	YccF domain-containing protein	NA	NA	NA	NA
WP_005315366.1\|4594202_4595513_+	trigger factor	NA	NA	NA	NA
WP_085941601.1\|4595620_4596223_+	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	5.4e-60	61.5
WP_017411865.1\|4596351_4597626_+\|protease	ATP-dependent protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	9.6e-131	57.5
WP_021140372.1\|4597767_4600122_+	endopeptidase La	A0A0R6PGP8	Moraxella_phage	3.6e-224	53.0
WP_005315375.1\|4600361_4600634_+	DNA-binding protein HU-beta	A7KV42	Bacillus_phage	5.0e-21	61.8
WP_088814373.1\|4600788_4602699_+	peptidylprolyl isomerase	NA	NA	NA	NA
WP_005315379.1\|4602939_4604532_-	ABC-F family ATPase	A0A2K9L0W2	Tupanvirus	1.1e-56	27.4
WP_042467894.1\|4604768_4606424_-	cation acetate symporter	NA	NA	NA	NA
WP_005315383.1\|4606420_4606732_-	DUF485 domain-containing protein	NA	NA	NA	NA
WP_005315390.1\|4606840_4607467_-	3'-5' exonuclease	NA	NA	NA	NA
WP_076611341.1\|4608004_4608922_-\|transposase	IS5-like element ISAs4 family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP047375

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

7364 : 52975

Vibrio_phage(62.5%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_159364953.1\|7364_8579_-\|transposase	IS256-like element ISAs3 family transposase	A0A218MNI5	uncultured_virus	4.3e-48	47.9
WP_155268746.1\|8804_8942_-	hypothetical protein	NA	NA	NA	NA
WP_159365022.1\|9041_10586_-	T3SS effector inositol phosphatase Ati2	NA	NA	NA	NA
WP_159365023.1\|10629_11079_-	Ati1 family type III secretion system chaperone	NA	NA	NA	NA
WP_076611341.1\|11423_12341_-\|transposase	IS5-like element ISAs4 family transposase	A0A1V0E8E1	Vibrio_phage	4.4e-93	55.8
WP_011899437.1\|12923_13952_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_017411843.1\|14585_15251_-	HrpE/YscL family type III secretion apparatus protein	NA	NA	NA	NA
WP_159365000.1\|15229_15856_-	type III secretion system sorting platform protein AscK	NA	NA	NA	NA
WP_005320809.1\|15852_16581_-	EscJ/YscJ/HrcJ family type III secretion inner membrane ring protein	NA	NA	NA	NA
WP_005320806.1\|16599_16938_-	EscI/YscI/HrpB family type III secretion system inner rod protein	NA	NA	NA	NA
WP_005320804.1\|16937_17492_-	YopR family type III secretion effector	NA	NA	NA	NA
WP_005320802.1\|17488_17842_-	YscG family type III secretion protein	NA	NA	NA	NA
WP_042468159.1\|17841_18099_-	EscF/YscF/HrpA family type III secretion system needle major subunit	NA	NA	NA	NA
WP_159365001.1\|18091_18304_-	EscE/YscE/SsaE family type III secretion system needle protein co-chaperone	NA	NA	NA	NA
WP_159365002.1\|18266_19571_-	EscD/YscD/HrpQ family type III secretion system inner membrane ring protein	NA	NA	NA	NA
WP_005320794.1\|19567_21406_-	EscC/YscC/HrcC family type III secretion system outer membrane ring protein	NA	NA	NA	NA
WP_159365003.1\|21393_21819_-	YscB family type III secretion system chaperone	NA	NA	NA	NA
WP_017411837.1\|21834_22650_-	T3SS regulon anti-activator ExsD family protein	NA	NA	NA	NA
WP_159365004.1\|22769_23585_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_042468163.1\|23930_24332_-	type III secretion system chaperone YscW	NA	NA	NA	NA
WP_005320785.1\|24328_24562_-	T3SS regulon translocated regulator ExsE family protein	NA	NA	NA	NA
WP_017411835.1\|24564_25008_-	glycosyl transferase	NA	NA	NA	NA
WP_159365005.1\|25143_26040_-	type III secretion system translocon subunit AopD	NA	NA	NA	NA
WP_159365006.1\|26052_27246_-	type III secretion system translocon subunit AopB	NA	NA	NA	NA
WP_042468166.1\|27193_27730_-	CesD/SycD/LcrH family type III secretion system chaperone	NA	NA	NA	NA
WP_017411832.1\|27739_28825_-	hypothetical protein	NA	NA	NA	NA
WP_159365007.1\|28834_29119_-	type III secretion protein	NA	NA	NA	NA
WP_005320772.1\|29158_29614_-	type III secretion system regulator LcrR	NA	NA	NA	NA
WP_042468167.1\|29610_31728_-	EscV/YscV/HrcV family type III secretion system export apparatus protein	NA	NA	NA	NA
WP_020379598.1\|31708_32059_-	type III secretion system chaperone AscY	NA	NA	NA	NA
WP_005320766.1\|32055_32421_-	type III secretion system protein AscX	NA	NA	NA	NA
WP_005320764.1\|32417_32789_-	type III secretion chaperone SycN	NA	NA	NA	NA
WP_005320760.1\|32785_33067_-	TyeA family type III secretion system gatekeeper subunit	NA	NA	NA	NA
WP_042468168.1\|33047_33926_-	YopN family type III secretion system gatekeeper subunit	NA	NA	NA	NA
WP_159365025.1\|34115_35438_+	EscN/YscN/HrcN family type III secretion system ATPase	NA	NA	NA	NA
WP_017411827.1\|35434_35896_+	type III secretion system central stalk protein AscO	NA	NA	NA	NA
WP_005320747.1\|37446_38373_+	YscQ/HrcQ family type III secretion apparatus protein	NA	NA	NA	NA
WP_042468169.1\|38369_39023_+	EscR/YscR/HrcR family type III secretion system export apparatus protein	NA	NA	NA	NA
WP_005320743.1\|39024_39291_+	EscS/YscS/HrcS family type III secretion system export apparatus protein	NA	NA	NA	NA
WP_005320741.1\|39287_40076_+	EscT/YscT/HrcT family type III secretion system export apparatus protein	NA	NA	NA	NA
WP_005320739.1\|40072_41131_+	EscU/YscU/HrcU family type III secretion system export apparatus switch protein	NA	NA	NA	NA
WP_017411822.1\|42064_42445_+	hypothetical protein	NA	NA	NA	NA
WP_011899444.1\|44768_45629_+	alpha/beta hydrolase	A2RQC8	Archaeal_BJ1_virus	5.3e-08	21.8
WP_076611341.1\|45924_46842_-\|transposase	IS5-like element ISAs4 family transposase	A0A1V0E8E1	Vibrio_phage	4.4e-93	55.8
WP_159365008.1\|47020_47311_-	CopG family transcriptional regulator	NA	NA	NA	NA
WP_042469195.1\|47310_47949_-	AAA family ATPase	A0A222YXS3	Escherichia_phage	4.9e-43	44.8
WP_076611341.1\|48792_49710_-\|transposase	IS5-like element ISAs4 family transposase	A0A1V0E8E1	Vibrio_phage	4.4e-93	55.8
WP_159365010.1\|50354_50486_-	DUF45 domain-containing protein	NA	NA	NA	NA
WP_076611341.1\|50556_51474_-\|transposase	IS5-like element ISAs4 family transposase	A0A1V0E8E1	Vibrio_phage	4.4e-93	55.8
WP_076611341.1\|52057_52975_+\|transposase	IS5-like element ISAs4 family transposase	A0A1V0E8E1	Vibrio_phage	4.4e-93	55.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP047374

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP047375

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection