CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP043846	Staphylococcus epidermidis strain ATCC 12228 plasmid unnamed, complete sequence	0 crisprs	NA	0	0	0	0
NZ_CP043845	Staphylococcus epidermidis strain ATCC 12228 chromosome, complete genome	2 crisprs	cas3,csa3,DEDDh,DinG	0	0	5	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP043845_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP043845_1

86986-87075

Orphan

Consensus_repeat	Method
TTTACATTTTTAAAAAATGCATAAGAGCCACT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP043845_1

>merge|NZ_CP043845|1|86986-87075|CRISPRCasFinder
TTTACATTTTTAAAAAATGCATAAGAGCCACTTACTATCATAGATTGTTTTGCTTCGGTTTACATTTTTCAAAAATGCATAAGAGCCACT

>NZ_CP043845|1|1|86986-87075|CRISPRCasFinder
TTTACATTTTTAAAAAATGCATAAGAGCCACT	TACTATCATAGATTGTTTTGCTTCGG
TTTACATTTTTCAAAAATGCATAAGAGCCACT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP043845.1\|WP_002470210.1\|91003_92167_-\|NarK/NasA-family-nitrate-transporter	unknown	unknown	gnl\|CDD\|225133
NZ_CP043845.1\|WP_002469526.1\|78202_78433_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043845.1\|WP_002469202.1\|86551_86902_+\|DUF4889-domain-containing-protein	unknown	unknown	gnl\|CDD\|374445
NZ_CP043845.1\|WP_002438352.1\|77744_78200_-\|copper-binding-protein	unknown	unknown	unknown
NZ_CP043845.1\|WP_002470205.1\|83760_85866_+\|AraC-family-transcriptional-regulator-Rsp	unknown	unknown	gnl\|CDD\|197666
NZ_CP043845.1\|WP_002456063.1\|80621_82067_-\|PTS-sucrose-transporter-subunit-IIBC	unknown	unknown	gnl\|CDD\|131051
NZ_CP043845.1\|WP_077431457.1\|89058_89697_-\|nitroreductase-family-protein	unknown	unknown	gnl\|CDD\|380314
NZ_CP043845.1\|WP_002485239.1\|87124_88405_-\|cation:dicarboxylase-symporter-family-transporter	unknown	unknown	gnl\|CDD\|183075
NZ_CP043845.1\|WP_002438319.1\|95294_95897_-\|nitrate-reductase-molybdenum-cofactor-assembly-chaperone	unknown	unknown	gnl\|CDD\|225091
NZ_CP043845.1\|WP_011082779.1\|85896_86361_+\|pyridoxamine-5'-phosphate-oxidase-family-protein	unknown	unknown	gnl\|CDD\|226389
NZ_CP043845.1\|WP_002438321.1\|94624_95302_-\|respiratory-nitrate-reductase-subunit-gamma	unknown	unknown	gnl\|CDD\|376889
NZ_CP043845.1\|WP_001831592.1\|94152_94605_-\|GAF-domain-containing-protein	unknown	unknown	gnl\|CDD\|379056
NZ_CP043845.1\|WP_002485230.1\|92423_93080_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225107
NZ_CP043845.1\|WP_002438330.1\|89852_90299_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_CP043845.1\|WP_002438353.1\|77449_77719_-\|DUF1775-domain-containing-protein	unknown	unknown	gnl\|CDD\|260082
NZ_CP043845.1\|WP_011082778.1\|78573_78978_-\|copper-binding-protein	unknown	unknown	gnl\|CDD\|225247
NZ_CP043845.1\|WP_002438349.1\|79584_80532_+\|magnesium-transporter-CorA-family-protein	unknown	unknown	gnl\|CDD\|213361
NZ_CP043845.1\|WP_002456059.1\|93108_94143_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|226951
NZ_CP043845.1\|WP_001831516.1\|82220_82598_+\|YbgA-family-protein	unknown	unknown	gnl\|CDD\|377982
NZ_CP043845.1\|WP_001831482.1\|88569_88935_-\|DUF3139-domain-containing-protein	unknown	unknown	gnl\|CDD\|371476

Protein	Function_ID	Function_description	E-value
NZ_CP043845.1\|WP_002470210.1\|91003_92167_-\|NarK/NasA-family-nitrate-transporter	gnl\|CDD\|225133	COG2223, NarK, Nitrate/nitrite transporter [Inorganic ion transport and metabolism].	5.70985e-110
NZ_CP043845.1\|WP_002456059.1\|93108_94143_-\|sensor-histidine-kinase	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	2.43496e-57
NZ_CP043845.1\|WP_002469202.1\|86551_86902_+\|DUF4889-domain-containing-protein	gnl\|CDD\|374445	pfam16230, DUF4889, Domain of unknown function (DUF4889). This family consists of uncharacterized proteins around 110 residues in length and is mainly found in various Staphylococcus aureus species. The function of this family is unknown.	3.01878e-26
NZ_CP043845.1\|WP_002470205.1\|83760_85866_+\|AraC-family-transcriptional-regulator-Rsp	gnl\|CDD\|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	1.10392e-18
NZ_CP043845.1\|WP_002456063.1\|80621_82067_-\|PTS-sucrose-transporter-subunit-IIBC	gnl\|CDD\|131051	TIGR01996, Includes:_Phosphotransferase_enzyme_IIB_component, PTS system, sucrose-specific IIBC component. This model represents the fused enzyme II B and C components of the sucrose-specific PTS sugar transporter system. Sucrose is converted to sucrose-6-phosphate in the process of translocation into the cell. Some of these transporters lack their own IIA domains and instead use the glucose IIA protein (IIAglc or Crr). The exceptions to this rule are Staphylococci, Streptococci, Lactococci, Lactobacilli, etc. which contain their own A domain as a C-terminal fusion. This family is closely related to the trehalose transporting PTS IIBC enzymes and the B and C domains of each are described by subfamily-domain level TIGRFAMs models (TIGR00826 and TIGR00852, respectively).	0
NZ_CP043845.1\|WP_001831482.1\|88569_88935_-\|DUF3139-domain-containing-protein	gnl\|CDD\|371476	pfam11337, DUF3139, Protein of unknown function (DUF3139). This family of proteins with unknown function appears to be restricted to Firmicutes.	9.91056e-13
NZ_CP043845.1\|WP_002485239.1\|87124_88405_-\|cation:dicarboxylase-symporter-family-transporter	gnl\|CDD\|183075	PRK11283, gltP, glutamate/aspartate:proton symporter; Provisional.	1.44272e-163
NZ_CP043845.1\|WP_002438319.1\|95294_95897_-\|nitrate-reductase-molybdenum-cofactor-assembly-chaperone	gnl\|CDD\|225091	COG2180, NarJ, Nitrate reductase delta subunit [Energy production and conversion].	2.14105e-51
NZ_CP043845.1\|WP_011082779.1\|85896_86361_+\|pyridoxamine-5'-phosphate-oxidase-family-protein	gnl\|CDD\|226389	COG3871, COG3871, Uncharacterized stress protein (general stress protein 26) [General function prediction only].	3.90875e-39
NZ_CP043845.1\|WP_002438321.1\|94624_95302_-\|respiratory-nitrate-reductase-subunit-gamma	gnl\|CDD\|376889	pfam02665, Nitrate_red_gam, Nitrate reductase gamma subunit. This family is the gamma subunit of the nitrate reductase enzyme, the gamma subunit is a b-type cytochrome that receives electrons from the quinone pool. It then transfers these via the iron-sulfur clusters of the beta subunit to the molybdenum cofactor found in the alpha subunit. The nitrate reductase enzyme, EC:1.7.99.4 catalyzes the conversion of nitrite to nitrate via the reduction of an acceptor. The nitrate reductase enzyme is composed of three subunits. Nitrate is the most widely used alternative electron acceptor after oxygen.	7.03174e-110
NZ_CP043845.1\|WP_001831592.1\|94152_94605_-\|GAF-domain-containing-protein	gnl\|CDD\|379056	pfam13185, GAF_2, GAF domain.	2.00355e-05
NZ_CP043845.1\|WP_002485230.1\|92423_93080_-\|response-regulator-transcription-factor	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.66665e-75
NZ_CP043845.1\|WP_002438330.1\|89852_90299_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	6.29821e-18
NZ_CP043845.1\|WP_002438353.1\|77449_77719_-\|DUF1775-domain-containing-protein	gnl\|CDD\|260082	cd08545, YcnI_like, Reeler-like domain of YcnI and similar proteins. YcnI is a copper-responsive gene of Bacillus subtilis. It is homologous to an uncharacterized protein from Nocardia farcinica, which shares a conserved three-dimensional structure with cohesins and the reeler domain. Some members in this YcnI_like family have C-terminal domains (DUF461) that may bind copper.	2.90826e-15
NZ_CP043845.1\|WP_011082778.1\|78573_78978_-\|copper-binding-protein	gnl\|CDD\|225247	COG2372, CopC, Uncharacterized protein, homolog of Cu resistance protein CopC [General function prediction only].	2.83287e-22
NZ_CP043845.1\|WP_002438349.1\|79584_80532_+\|magnesium-transporter-CorA-family-protein	gnl\|CDD\|213361	cd12827, EcCorA_ZntB-like_u2, uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family. A uncharacterized subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB (EcCorA-ZntB_like) family of the MIT superfamily of essential membrane proteins involved in transporting divalent cations (uptake or efflux) across membranes.The EcCorA-ZntB-like family includes the Mg2+ transporters Escherichia coli and Salmonella typhimurium CorAs, which can also transport Co2+, and Ni2+. Structures of the intracellular domain of EcCorA-ZntB-like family members, Vibrio parahaemolyticus and Salmonella typhimurium ZntB, form funnel-shaped homopentamers, the tip of the funnel is formed from two C-terminal transmembrane (TM) helices from each monomer, and the large opening of the funnel from the N-terminal cytoplasmic domains. The GMN signature motif of the MIT superfamily occurs just after TM1, mutation within this motif is known to abolish Mg2+ transport through Salmonella typhimurium CorA. Natural variants such as GVN and GIN, such as occur in some ZntB family proteins, may be associated with the transport of different divalent cations, such as zinc and cadmium. The functional diversity of MIT transporters may also be due to minor structural differences regulating gating, substrate selection, and transport.	1.20836e-108
NZ_CP043845.1\|WP_001831516.1\|82220_82598_+\|YbgA-family-protein	gnl\|CDD\|377982	pfam08349, DUF1722, Protein of unknown function (DUF1722). This domain of unknown function is found in bacteria and archaea and is homologous to the hypothetical protein ybgA from E. coli.	1.02229e-28
NZ_CP043845.1\|WP_077431457.1\|89058_89697_-\|nitroreductase-family-protein	gnl\|CDD\|380314	cd02137, MhqN-like, nitroreductase family protein similar to the NAD(P)H nitroreductase MhqN. A diverse subfamily of the nitroreductase family containing uncharacterized proteins; includes nitroreductases MhqN, YodC, YdgI, DrgA. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer.	1.70471e-60

>NZ_CP043845.1|WP_002469202.1|86551_86902_+|DUF4889-domain-containing-protein
MKNKKGLGIGLITIMVIVCIVLVIMMFVGGKKDSYYGIMKDSTTIDKMINTKNEKIEKNVELPKDANVSVKKEDFVMLFKDEKTGKITKVKKVDHDDVPHGLMSKIHDMGNMKHGM
>NZ_CP043845.1|WP_011082779.1|85896_86361_+|pyridoxamine-5'-phosphate-oxidase-family-protein
MCDKDIYNNKEMIILNKQQVTKAIEKVLNSSKIGVLSTAHHNKPNSRYMVFYNDDLNLYTKTNVNSLKVEEIENNPDAHILLGYNETTNNSFVEIDATIEVVKDQKVIDWLWETQDKTFFNSKEDPELCVLKVIPRSIKLMNDDELDTPATIEL
>NZ_CP043845.1|WP_002470205.1|83760_85866_+|AraC-family-transcriptional-regulator-Rsp
MTCFLNIYKEYHSPPERNINRIILMFSLTNDLKITINGETKDLGNHIAIINQSDIYFINSASNLVLLSIPVIYFYSKDNKFFKCYFDRHLLQSSSFVKTIILQAIQHLIKGENQDEQSISKIIQTLLKEAVIRYKKKYIPQIAVNHSVFTEGLTFIHSKVSQSLSLREVAQHCNISESYCSNLFARYLNMNFKDYFTSLKVIDSIKRLLSSEDSINAISEQSGFSSHTNFTNQFKNYLGCSPKQYRTIISKLDPLPSISFSDTDFSQYIELINQFEFSDHWATETTERDINEFYPQDQTKNSKAFIRFQNFNELFQFVFNEYYNIDLTSLPQAVIFINDITDISTREVNFNLLNRCFEKLFEKNIGLAMRLTSTNEFESIKEIILLFLNSHQDYKMNKKMVKFMLVFETENMSVNDIHLCHLKIKNKNKAIRYSITVEGLLHQNSSIDRTYDMMKRLNFDYYFIDIENLETKNSLITKRKSYLHSSTHFENYKQFILDSGIPSTKFVYNNLSLKCFKYTNNGTYPLQLSDLVCHLVALMRYGGGVSYQLIEDESPFIALFNRYGSPLPLMHLYKLIEPFLNEPLEIANNFLMSRKDGNYHFLLFNKINDRYLSDSQQRYVFKNTLSTNSLIIIKTLNHEHGAIQNLLPQTKQQFYIERSILDELDKSNQPKTELAIQHDHHLPFHVTLKHDEVKYICFKPS
>NZ_CP043845.1|WP_001831516.1|82220_82598_+|YbgA-family-protein
MKERGKIEKLWREEKYRVLFHDQNAYHSIRTLLKSPTTLGEVKEHITHALTITPTKGSVINAFEHMWGYFKKQCTQYEKQHSRELKALYIENQIDYFELLSFLKNLADKYAVEYLQQSTILNITK
>NZ_CP043845.1|WP_002456063.1|80621_82067_-|PTS-sucrose-transporter-subunit-IIBC
MSYKKSAEEILKAIGGEENLDAMAHCATRLRLVLNDESKVDEDTLSNMDVVKGTFSTGGQYQIIIGSGTVNKVFNELEKITGKEASTTSEVKDKSSKHMNPFQKFVKMLSDIFVPIIPAIVAGGLLMGLNNIFTAKDLFYDGKSIIDVHSQFSGLADMINIFANAPFTLLPILIGFSAAKRFGGNPYLGAALGMILVHPGLMSAYDFPKALEEGKAIPHWDVFGLHINEVGYQGQVLPMLVATYILATIEKWLRKVIPTVLDNLLTPLLSIFITAFITFLFVGPVTRQLGYWLSDGLTWLYEFGGAIGGLIFGLLYAPIVITGMHHSFIAVETTLIADATKTGGSFIFPIATMSNIAQGGAALAAFFIIKQNKKLKGVASAAGISALLGITEPAMFGVNLKLRYPFIGAVAGSGIGAAYISFFKVKAIALGTAGLPGFISINPTHAGWLHYLIGMLIAFVVSVVVTLVLSRRKTNKTAVES
>NZ_CP043845.1|WP_002438349.1|79584_80532_+|magnesium-transporter-CorA-family-protein
MITAYKHALHHPSQIIETEINHSASWINVVEPDREEIEGLMEFYNIPEDFIRDPLDSEESARIEYDEDTGYSLIIIDLPIVNSTNRRVLSFVTIPLGIIIGNGIVMTVCDAENEFLENFAKQEDINLKFHSRFALEILTTIANHYNRNLRLLNKSRIRIERELKNNITNKQLFKLMEVEKSLVYFLAALKGNDTIIKKLFRLPAIKRFEEDEELLEDLVIENNQAIETTELHQRILESITSSYASLLSNDMNNIMKTLTLFTVLLTLPTLVFSFFGMNVPLPIDDHSYVSWIIVVGISLILVAIVSIFLWKKQKL
>NZ_CP043845.1|WP_011082778.1|78573_78978_-|copper-binding-protein
MLVLKIMSKHSATLVIMFLITLLPIFQYQASAHATLEKSTPQQQGVIKDNPEAIKLEFNEPVNTKYSSVTLFDDKGKKIKDLKPITTGWSQTVVFSSEQIVNGTNTIEWHTVSADGHEVGDTFEFSVGKVRLKM
>NZ_CP043845.1|WP_002469526.1|78202_78433_-|hypothetical-protein
MLPKQSGIAWIMAMSVLVSLVVYMMTLTSDILEDILSFKLEVIMQFPYILSSISLIILFILFILKDMEKYGTGSFQ
>NZ_CP043845.1|WP_002438352.1|77744_78200_-|copper-binding-protein
MIAVISMSGHVWSQQVPLWSIIIRTIHLIGLTLWLGSLVYLICYAIKVKINQLTSVRRMLLKVNIIAVFMLVFTGILMAIDETNTLTLWNNVSAWSIYLVIKIAGIITMMLLGFYQTMRALRQRQQVHRFALMTELLIGMILIFAGIMMSK
>NZ_CP043845.1|WP_002438353.1|77449_77719_-|DUF1775-domain-containing-protein
MLRKLLLLTFIVFWGIGFFKYADAHVTLNPNESEPESYDKYDVRVPVEQNDHTMKVELDVPKGLNVESVKPIEGFKHHFLKIKKGTLLK
>NZ_CP043845.1|WP_002485239.1|87124_88405_-|cation:dicarboxylase-symporter-family-transporter
MALFKKKISLPTQVIIALVLGVIAGLLLYGHDDVANYIKPFGDVFLNLIKMIIIPIVFCSLALSISNLGDSKKVGSYGWKAILYFEIITTIAIGLGLIIGNLFKPGSGLDPDKLPKGDITKYQSSAHSAEQATTYGNHLIDTLVHIVPTNLFESMAKGELLPIIFFAVFFGLGLAAIGEKAEPVKGFLNGTLEAVFWMINKILKLAPIGVFAFICTTVMTFGASALIPLFKLLVVVVFAMVFFVIVVLGIVARMVGISIFSIMKILKSELLLAFSTSSSEAVLPIMMKKMERFGSPKDVTSFVIPIGYSFNLDGSALYQSIAALFVAQMYDIHLSLTEQLVLMATLMIASKGMAGVPGVSIVVLLTTLTSMNITAQGLALIIGVDRLLDMVRTCVNVIGNALSTVVIAKWENVYDKEKGQNYLNSI
>NZ_CP043845.1|WP_001831482.1|88569_88935_-|DUF3139-domain-containing-protein
MSKKQVIFRVIIILIISLILAIAFFFGLKAYQGHKNLELIDSYMSDHHLNDKVKKDKTSYSTKKGLYYKEVVFKDEPNVTYVIQPISTSKGIFIEGFDSETKKSIKKAKHSDFDQKYKPSK
>NZ_CP043845.1|WP_077431457.1|89058_89697_-|nitroreductase-family-protein
MQKLTRINDFNEVLNSRKSVKVFDENYKIPREEMDEIITKATKAPSSVNMQPWRIAVVESDEMKEKVKESFGFNSRQLTTSSAMLIIFGDLQNYEKAEQIYGDAVEQQLMTEDIKAQLLDWILPYYKNLSREGMKDIVNIDSSLMAMQLMLTAKAHGYDTNPIGGFDKENIADIIGYDSDRYVPVLAIAIGKKAQDAHDSVRLPIDDVREFL
>NZ_CP043845.1|WP_002438330.1|89852_90299_+|MarR-family-transcriptional-regulator
MYVENSYLSKQLCFLFYVSSKEIIKKYTDYLKEYGLTYTGYIVLMAIEDDEKLNIKKLGERVFLDSGTLTPLLKKLEKKNYVIRTREEQDERNLQISLTERGKDIQNVLSDISQSVFNEFNITQEETQNLVEDLQNFVTKNFDKTVEK
>NZ_CP043845.1|WP_002470210.1|91003_92167_-|NarK/NasA-family-nitrate-transporter
MNMKKGVSQLTLQTLSLVAGFMAWSIISPLMPFISQDVDISPGQISVILAIPVILGSVLRVPFGYLTNIVGAKWVFFWSFIVLLLPIFLLGQAQSPGMLMLSGFFLGIGGAIFSVGVTSVPKYFSKDKVGLANGIYGVGNIGTAVSSFCAPVLAGAIGWQNTVRSYLIILSIFAILMFFLGDKNEPKVKIPLMAQVKDLSKNYKLYYLSLWYFITFGAFVAFGIFLPNFLVDHFSIDKVDAGIRSGIFIALATFLRPVGGVIGDKFNAVQALIIDFVIMIIGALILSLSSHIVLFTIGCLAISICAGIGNGLIFKLVPSYFSKEAGSANGIVSMMGGLGGFFPPLVITFVTSITGSSHLAFFFLAIFGVIALITMIHLNKKEKAIRI
>NZ_CP043845.1|WP_002485230.1|92423_93080_-|response-regulator-transcription-factor
MKIVIADDHAVVRTGFSMILNYQEDMEVVATAADGVEAYQKVLEHRPDVLILDLSMPPGESGLIATSKISESFPETKILILTMFDDEEYLFHMLKSGAKGYILKNSPDEQLILAVRTVYQGETYVDMKLTTSLVNEFVNQSQTDEVSSSSDPFKILSKRELEILPLIAKGYGNKDIAEKLFVSVKTVEAHKTHIMTKLNLKSKPELVEYALKKKLLEF
>NZ_CP043845.1|WP_002456059.1|93108_94143_-|sensor-histidine-kinase
MLEQTDLSLEQLLKNYYETTNEKIVFVNRQGKIIAMNDAAKDILTEEDNYNAMTNAICHRCEGYSNEYDVQSCKDCFLETTQLQHSNFQVFMKTKDNEIKPFTAMYQNIDEQRGISAFTLQNVAPQIERQEKMYQQKMLHRSIQAQENERKRISRELHDSVIQDMLNIDVELRLLKYKHRDKVLAETSQRIEGLLSQLIDDIRNMSVELRPSSLDDLGIEAAFKSYFKQFEENYGMHIKYDSNIKGMRFDNEIETVVYRVVQEGVFNALKYAEVNEIEVSTHSDGKQLVAEVVDRGKGFSLDHHPKGSGLGLYGMRERAELVNGHVNIETHINRGTIITLDIPI
>NZ_CP043845.1|WP_001831592.1|94152_94605_-|GAF-domain-containing-protein
MEPESLKHNQHLQMNLDKLRAQEGYDFGGIALYDYHHTSSPIKWQYVSGNTNDRYKLIILRKGRGLAGMVMKTGKRMVIADVDTALSPEEKVKFPIILSESLTAVVAVPLWLENSMYGVLLLGQRNHQPLPQSLDQLNIEKQIGIFTEIN
>NZ_CP043845.1|WP_002438321.1|94624_95302_-|respiratory-nitrate-reductase-subunit-gamma
MLNQFVWVIYPYLCLAIFVIGHIARYKYDQFSWTAKSSEMIEKKRLKWGSLLFHLGIIPVFFGHVVGLLIPANWLEAIGVNNHIYHIGAVYIGSVFGIITLIGMLLLTLRRLSIKNVRRLSSFSDIFVNIVLLIILIMGCYSTLVTNAIQPEFDYRQTIAIWFRHLFMFSPNADLMLNVPWSFKLHILLGFTVFACWPFTRLVHVWSVPLSYMNRRYIVYRKNKI
>NZ_CP043845.1|WP_002438319.1|95294_95897_-|nitrate-reductase-molybdenum-cofactor-assembly-chaperone
MKISMEGSSVINLEQLSLYQDSLGYLGQQMNFPEKMTFHPKIFEETISKSHPGYEDLLAYREVMMNYTLSEIKAIYTDTFDFSKKHPLYMTFNKFDTQKERGQMLAKLKVLYEMFGLKMVDNELSDFLPLMLQFLQVADFKNDSRAQENLQLVIMIIEDGTYEMANTLAENNNPYAYVVSALRKTLKACIVPLKEVENHA

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Crispr_ID: NZ_CP043845_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP043845_2

1180086-1180181

Orphan

Consensus_repeat	Method
CATAAGTGACACAAGCAATTAAAAATTGCAGTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP043845_2

>merge|NZ_CP043845|2|1180086-1180181|CRISPRCasFinder
CATAAGTGACACAAGCAATTAAAAATTGCAGTGAAAAAGAGGAACGCTTGAGCAAAGCTCAAGCATAAGTGACACTAGCAATTAAAAATTGCAGTG

>NZ_CP043845|2|2|1180086-1180181|CRISPRCasFinder
CATAAGTGACACAAGCAATTAAAAATTGCAGTG	AAAAAGAGGAACGCTTGAGCAAAGCTCAAG
CATAAGTGACACTAGCAATTAAAAATTGCAGTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP043845.1\|WP_001831965.1\|1179092_1179446_+\|arsenate-reductase-family-protein	unknown	unknown	gnl\|CDD\|239334
NZ_CP043845.1\|WP_001831963.1\|1179619_1180000_+\|glycine-cleavage-system-protein-GcvH	unknown	unknown	gnl\|CDD\|234918
NZ_CP043845.1\|WP_002438995.1\|1186631_1187939_+\|Fe-S-cluster-assembly-protein-SufD	unknown	unknown	gnl\|CDD\|223791
NZ_CP043845.1\|WP_001831936.1\|1180638_1180935_+\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP043845.1\|WP_011082631.1\|1181187_1182213_+\|methionine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224058
NZ_CP043845.1\|WP_001831974.1\|1177104_1177821_+\|type-I-3-dehydroquinate-dehydratase	unknown	unknown	gnl\|CDD\|184156
NZ_CP043845.1\|WP_011082628.1\|1174220_1174826_+\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|366010
NZ_CP043845.1\|WP_001831893.1\|1184003_1184162_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043845.1\|WP_001831944.1\|1185775_1186537_+\|Fe-S-cluster-assembly-ATPase-SufC	unknown	unknown	gnl\|CDD\|223473
NZ_CP043845.1\|WP_001831981.1\|1177901_1178444_+\|nitroreductase	unknown	unknown	gnl\|CDD\|380312
NZ_CP043845.1\|WP_001831967.1\|1184336_1184528_+\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|225777
NZ_CP043845.1\|WP_001831988.1\|1182921_1183734_+\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224381
NZ_CP043845.1\|WP_001831907.1\|1178626_1178950_-\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP043845.1\|WP_001831939.1\|1184593_1185454_-\|DUF368-domain-containing-protein	unknown	unknown	gnl\|CDD\|224946
NZ_CP043845.1\|WP_001829623.1\|1175096_1175597_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|372596
NZ_CP043845.1\|WP_002438972.1\|1175679_1175808_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043845.1\|WP_002457221.1\|1176521_1176944_-\|Organic-hydroperoxide-resistance-protein-like-1	unknown	unknown	gnl\|CDD\|274649
NZ_CP043845.1\|WP_002485418.1\|1182205_1182901_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224922
NZ_CP043845.1\|WP_001830507.1\|1176182_1176338_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043845.1\|WP_001831968.1\|1180259_1180646_+\|topiosmerase	unknown	unknown	gnl\|CDD\|224572

Protein	Function_ID	Function_description	E-value
NZ_CP043845.1\|WP_001831965.1\|1179092_1179446_+\|arsenate-reductase-family-protein	gnl\|CDD\|239334	cd03036, ArsC_like, Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX) function as protein disulfide oxidoreductases, altering the redox state of target proteins via the reversible oxidation of the active site dithiol. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from glutathione via GRX, through a single catalytic cysteine.	1.66742e-56
NZ_CP043845.1\|WP_001831963.1\|1179619_1180000_+\|glycine-cleavage-system-protein-GcvH	gnl\|CDD\|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	1.8319e-69
NZ_CP043845.1\|WP_002438995.1\|1186631_1187939_+\|Fe-S-cluster-assembly-protein-SufD	gnl\|CDD\|223791	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones].	2.49596e-133
NZ_CP043845.1\|WP_001831936.1\|1180638_1180935_+\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	1.51609e-11
NZ_CP043845.1\|WP_011082631.1\|1181187_1182213_+\|methionine-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	6.12365e-167
NZ_CP043845.1\|WP_001831974.1\|1177104_1177821_+\|type-I-3-dehydroquinate-dehydratase	gnl\|CDD\|184156	PRK13575, PRK13575, type I 3-dehydroquinate dehydratase.	1.58421e-151
NZ_CP043845.1\|WP_011082628.1\|1174220_1174826_+\|histidine-phosphatase-family-protein	gnl\|CDD\|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	1.78585e-50
NZ_CP043845.1\|WP_001831944.1\|1185775_1186537_+\|Fe-S-cluster-assembly-ATPase-SufC	gnl\|CDD\|223473	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones].	1.04582e-150
NZ_CP043845.1\|WP_001831981.1\|1177901_1178444_+\|nitroreductase	gnl\|CDD\|380312	cd02135, YdjA-like, nitroreductase family protein similar to Escherichia coli YdjA. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase YdjA from Escherichia coli. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer. Members of this family are also called NADH dehydrogenase, oxygen-insensitive NAD(P)H nitrogenase or dihydropteridine reductase.	7.82596e-53
NZ_CP043845.1\|WP_001831967.1\|1184336_1184528_+\|CsbD-family-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	0.000312009
NZ_CP043845.1\|WP_001831907.1\|1178626_1178950_-\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	1.68543e-25
NZ_CP043845.1\|WP_001831939.1\|1184593_1185454_-\|DUF368-domain-containing-protein	gnl\|CDD\|224946	COG2035, COG2035, Predicted membrane protein [Function unknown].	5.03423e-64
NZ_CP043845.1\|WP_001829623.1\|1175096_1175597_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|372596	pfam13420, Acetyltransf_4, Acetyltransferase (GNAT) domain.	1.80445e-49
NZ_CP043845.1\|WP_001831988.1\|1182921_1183734_+\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	6.16978e-110
NZ_CP043845.1\|WP_002457221.1\|1176521_1176944_-\|Organic-hydroperoxide-resistance-protein-like-1	gnl\|CDD\|274649	TIGR03561, organ_hyd_perox, peroxiredoxin, Ohr subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein Ohr, or organic hydroperoxide resistance protein. [Cellular processes, Detoxification].	2.58332e-60
NZ_CP043845.1\|WP_002485418.1\|1182205_1182901_+\|ABC-transporter-permease	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	3.39329e-98
NZ_CP043845.1\|WP_001831968.1\|1180259_1180646_+\|topiosmerase	gnl\|CDD\|224572	COG1658, COG1658, Small primase-like proteins (Toprim domain) [DNA replication, recombination, and repair].	1.04994e-30

>NZ_CP043845.1|WP_001831963.1|1179619_1180000_+|glycine-cleavage-system-protein-GcvH
MAVPSEFKYSKEHEWVKIENNVATVGITEYAQNELGDIVFVELPETDDELNEGDTFGSVESVKTVSELYAPISGKIVEVNEELEDSPEFVNESPYEKAWMVKIEISDDSQLEELLSADQYSEMIGE
>NZ_CP043845.1|WP_001831965.1|1179092_1179446_+|arsenate-reductase-family-protein
MIKFYQYPKCTTCKKAAKFLDEHDVNYESIDIVQHTPTKKEFKNIVDKTGVNINKLFNTHGIKYRELNLKEKLKNMSDDEKLELLASDGMLVKRPLAISGNHLTLGFKENEYQHQWL
>NZ_CP043845.1|WP_001831907.1|1178626_1178950_-|thioredoxin-family-protein
MKNIHQTEEFNSTIGSTDPVIIKFEADWCPDCKAMDMWIDPIVEKYNNYQWYVVDRDELEDVTTENDVMGIPSILIFQNGKKLAHLHSANAKSPEQVESFLTEHLDQ
>NZ_CP043845.1|WP_001831981.1|1177901_1178444_+|nitroreductase
MELQEAISNRRSVKKFKHDMVVDDQTVYDAIYKATDAPNHGMREPWRLVHISKDKLGDFSRDITRFAFPDSPDKREDHFHAVTNLGGMLLLILKDDPRQRQSRENYFAFGAFAQNLMLLLYEAGIGTCWKSPQYIFDPKIRKALGVKDNEILAGFLYLTDLEEVPTKAKRKNKNLITEFE
>NZ_CP043845.1|WP_001831974.1|1177104_1177821_+|type-I-3-dehydroquinate-dehydratase
MTHVDIAATIAPEDKLSKTLLKDIKVNEESIDIIELRIDQWPSFNKALLNEVIKQLKIFHLKILVTYRTSVQGGKGAVNEQEYLNILGELIECPQFDMIDIEWSSAVKIEKYTHLVQRAQQKGLEVVLSHHNFQETPALDELKFIYFKMQKLNPEYLKLAVMPKCQEDVLHLLEAMSLTAKHTTCRIVGISMSSLGKVSRIAQGVFGGTLSYGCIEEPQAPGQIHVSKLKSMVSFYED
>NZ_CP043845.1|WP_002457221.1|1176521_1176944_-|Organic-hydroperoxide-resistance-protein-like-1
MAVQYETKATNVGGRKGHVHTDDNAINVDVLPPQQADGKATNPEQLFAAGYASCFNGAFDLILKQNKVRDAEPEVTLTVRLEDDPDAESPKLSVDIHAKVKNVLSQEDAEKYLQDAHDFCPYSKATRGNIDVNLNVEVVE
>NZ_CP043845.1|WP_001830507.1|1176182_1176338_+|hypothetical-protein
MYKEYNLTQHTLPMETSVLIPTNDISRHVNDIVETIPDTEFDEFRHHRGLI
>NZ_CP043845.1|WP_002438972.1|1175679_1175808_-|hypothetical-protein
MINSFQSHHFPIDKNIKLILKTIFKYVVNNVFYSNKTIIAYF
>NZ_CP043845.1|WP_001829623.1|1175096_1175597_-|GNAT-family-N-acetyltransferase
MNNIRLLNQNDLDSYIELMKFGHHNYEWDRYYLENVSIDRLKTILSNHTDYWNIFGAFEDDELVATCTLKQMNYVGKCHKAILENNFVKNNDEIVNRELINHIIQYAKEQNIETLMIAIASNNISAKVFFSSIGFENLAFEKNASKIGNEYFDENWLIYSTTESSD
>NZ_CP043845.1|WP_011082628.1|1174220_1174826_+|histidine-phosphatase-family-protein
MKRCLQLVKTLYLMRHGQTVFNLKGKIQGASDSPLTALGVQQANAAQQYFKTKNIHFDYLYSSPQQRACDTLENAVPNQQYWCVKDLKEWGFGLFEGESIELLRAIKQPRYLYGDAVVPFGGESRSEVEHRVYRALYEMMDTTDGETILAVSHGSTIGLFVRNILGYDKGSKFEIGNCNIVKFEYDGEEFIFKDLINPIKK
>NZ_CP043845.1|WP_001831968.1|1180259_1180646_+|topiosmerase
MAIVNKVIIVEGKSDKKRVQQVIAEPANIICTHGTMSIDKIDNMIETLYDKQVYVLADSDDEGEKIRKWFKRYLSESEHIYVDKTFCEVAKCPKNYLAHVLSRYGFNVKKEKKLMNNLKTERLVLVNE
>NZ_CP043845.1|WP_001831936.1|1180638_1180935_+|thioredoxin-family-protein
MNKLKDIEDITVNFNKEKHLIFGYTPMCGTCKISERMLDIANEILQLPIKKIDLNFYPEWSKEKQIMSVPVLLLMRREEEIKRIYAFQSVTYLLENLK
>NZ_CP043845.1|WP_011082631.1|1181187_1182213_+|methionine-ABC-transporter-ATP-binding-protein
MIKLNQIVKRYHTKDKDVLAVDHVDLNIESGSIFGVIGFSGAGKSTLIRMFNNLESPTSGEIIIDGDNISQLSKSQLRKKRQKVSMIFQHFNLLWSRNVLKNVTFPLEIAGVPSGLAKQKALELIELVGLKGRESAYPSELSGGQKQRVGIARALANDPDVLLCDEATSALDPQTTDEILDLLLKVREQQNLTIVLITHEMHVIRRMCDEVAVMENGKVIEQGAVSKVFENPQHEVTKRFVKDDLNDDFEDSLEYLEPLDHDAYIVRLNFTGENTTEPIISYMTKTHNIDVNILEADIKNTKNGSLGFLVIHIPHISEEHFKQFKHNLHEQHVNVEVLKHG
>NZ_CP043845.1|WP_002485418.1|1182205_1182901_+|ABC-transporter-permease
MGKSYGEIFHEMVTMPNVQWPEVWQAILETLYMTVVSTLFAFVFGLILGVLLFLSAKSNSLAAKIFYTIVSFIVNLFRAIPFIILILLLIPFTSILLGTISGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTSIVVRKVLLPEAMPALVSDITVTAIALVGSTAIAGVIGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQFLGDWLTNKIDKR
>NZ_CP043845.1|WP_001831988.1|1182921_1183734_+|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein
MKKLFGIILVLALTIALAACGGGKDKEKTITVGASPAPHAEILEKAKPLLKKKGYDLKIKSINDYTTPNKLLDKGEIDANFFQHTPYLNTESKEKGYKIESAGNVELEPMAVYSKKYKSLKDLPKGATVYVSNNPAEQGRFLKFFVDEGLIKLKKGVKIENAKFDDITENKKDIKFNNKQSAEYLPKIYQNQDADAVIINSNYAIDQKLSPKKDSIALESPKDNPYANLIAVKKGHKDDKNIKVLMEVLQSKEIQDYIKDKYDGAVVPAK
>NZ_CP043845.1|WP_001831893.1|1184003_1184162_-|hypothetical-protein
MKFITIKAITEKGLDKKVNQFLKSHPQIEIIKFDYQMGYSGVSVGILYRDNI
>NZ_CP043845.1|WP_001831967.1|1184336_1184528_+|CsbD-family-protein
MAEDKFEQAKGNIKETVGNATDNKELEKDGKGDKASGKAKEAVENVKEKANDVIDKFKGNKGD
>NZ_CP043845.1|WP_001831939.1|1184593_1185454_-|DUF368-domain-containing-protein
MKKFKWINIFKGFGMGTSDLVPGVSGGTIALLLGIYDDFISSISGLFSRRFWPSLKFLLPILVGMLIAIGLLSQLFNYLLSQHHIPTMLFFTGLILGIIPYLLTISNFKKNFSIIHYFILLLGIAIIVVFALLNHGDKHSGETLTLSFSLIIKYFIAGVFASSAMLLPGISGSFMLLVFGVYGTLMYAISELLHFNLNALPIILIVGFGIVTGFMISSRLIQYCLHQHPTMTFALIIGFVIGSLYAVFPGFPKDLIQWIISFFLLITGFLVSYVLGKITAKNEASF
>NZ_CP043845.1|WP_001831944.1|1185775_1186537_+|Fe-S-cluster-assembly-ATPase-SufC
MSSTLEIKDLHVSIEDKEILKGVNLTINTGEIHAIMGPNGTGKSTLSSAIMGHPSYEVTQGEVLLDGVNILELDVDERAKAGLFLAMQYPSEITGVTNADFMRSAINAKREEGQEINLMQFIKKLDKQMDFLDIDKDMAQRYLNEGFSGGEKKRNEILQLMMLEPKFAILDEIDSGLDIDALKVVSKGINQMRGEEFGALMITHYQRLLNYITPDKVHVMYGGKVVKSGGPELAKRLEEEGYEWVKEEFGAAE
>NZ_CP043845.1|WP_002438995.1|1186631_1187939_+|Fe-S-cluster-assembly-protein-SufD
MTTKTLNISEEQLVDYSKAHNEPSWMTELRKKALKLTETLEMPKPDKTKLRKWDFDTFKQHHTTGDAYTQLTDLPKSVKEIIDVENSENLIIQHNNELAYTQVSDQAKHDGVIIEGLSEALVNHSDLVQKYFMTKAVDVDEHRLTALHTALVNGGIFVYVPKNTVVEHPIQYVVLHDDEQASFYNHVIIVTEESAEVTYVENYLSTTSGEDNQLNIVSEVIAGANSNVTYGSVDYLDKGFTGHIIRRGSADADASINWALGLMNEGSQIIDNTTNLNGDRSTSALKSVVVGTGDQKINLTSKIVQYGKETDGYILKHGVMKENASSVFNGIGYIKRGGTKSIANQESRVLMLSENARGDANPILLIDEDDVEAGHAASVGRVDPEQLYYLMSRGISRAEAERLVIHGFLDPVVRELPIDDVKRQLREVIERKVSK

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1062014 : 1072549

Staphylococcus_phage(22.22%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001830355.1\|1062014_1062854_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	1.2e-60	43.0
WP_011082622.1\|1062995_1063088_+	hypothetical protein	NA	NA	NA	NA
WP_001830351.1\|1063056_1064163_+	glycosyltransferase family 2 protein	A8CG95	Salmonella_phage	6.3e-62	43.2
WP_002438881.1\|1064232_1065198_-	HAMP domain-containing histidine kinase	A0A1V0SGX0	Hokovirus	1.8e-17	30.6
WP_001830352.1\|1065287_1065977_-	response regulator transcription factor	W8CYM9	Bacillus_phage	3.4e-34	35.2
WP_001830332.1\|1065951_1066425_-	DoxX family protein	NA	NA	NA	NA
WP_001830329.1\|1066475_1066913_-	hypothetical protein	NA	NA	NA	NA
WP_010959136.1\|1067318_1067417_+	hypothetical protein	NA	NA	NA	NA
WP_002485887.1\|1067508_1067664_-	hypothetical protein	A0A146ICT8	Staphylococcus_phage	4.4e-14	77.6
WP_001830331.1\|1068013_1068613_-	hypothetical protein	NA	NA	NA	NA
WP_001830330.1\|1068714_1069428_-	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	1.6e-55	44.8
WP_001830341.1\|1069428_1069848_-	6-carboxytetrahydropterin synthase QueD	NA	NA	NA	NA
WP_001830328.1\|1069852_1070524_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	4.1e-64	55.7
WP_001830349.1\|1070820_1071408_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	4.4e-38	42.9
WP_001830323.1\|1071397_1072549_+	anthranilate synthase component I family protein	A0A0B5J984	Pandoravirus	7.5e-26	39.6

DBSCAN-SWA_2

1093975 : 1104409

uncultured_Caudovirales_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002438897.1\|1093975_1095481_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	5.5e-61	34.0
WP_001832596.1\|1095764_1096265_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	1.1e-50	70.1
WP_001829684.1\|1096278_1097154_-	DMT family transporter	NA	NA	NA	NA
WP_001829589.1\|1097908_1098307_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	2.0e-71	100.0
WP_001829582.1\|1098269_1100375_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	100.0
WP_001829597.1\|1100493_1101462_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	3.9e-185	100.0
WP_002456931.1\|1101436_1101700_+	hypothetical protein	A0A2H4IYB4	uncultured_Caudovirales_phage	5.5e-17	100.0
WP_002438902.1\|1101715_1102690_+	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	5.9e-165	99.7
WP_002438903.1\|1102673_1103633_+	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	4.1e-17	100.0
WP_001829596.1\|1103629_1104409_+	ATP-binding cassette domain-containing protein	W6JKT0	Anomala_cuprea_entomopoxvirus	5.1e-18	33.6

DBSCAN-SWA_3

1286974 : 1291552

uncultured_Mediterranean_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001829295.1\|1286974_1287238_+	DUF4176 domain-containing protein	A0A1X9I6T6	Streptococcus_phage	1.5e-09	41.4
WP_107362610.1\|1287348_1287444_+	type I toxin-antitoxin system Fst family toxin	NA	NA	NA	NA
WP_001829258.1\|1287510_1287714_-\|transposase	transposase	A0A0N7GFG6	Staphylococcus_phage	3.3e-09	80.0
WP_107362609.1\|1287805_1288210_+	glucose-6-phosphate dehydrogenase	E3SKF6	Synechococcus_phage	1.9e-08	31.3
WP_071813278.1\|1288244_1288310_+	hypothetical protein	NA	NA	NA	NA
WP_077431490.1\|1288316_1288466_+	hypothetical protein	M4SJ15	Cyanophage	3.5e-08	51.0
WP_002469315.1\|1288798_1289176_+	glucose-6-phosphate 1-dehydrogenase	NA	NA	NA	NA
WP_002485410.1\|1289294_1289537_+	UVRA	A0A1B1IVR3	uncultured_Mediterranean_phage	7.9e-10	48.6
WP_002485412.1\|1289539_1291552_+	ATP-binding cassette domain-containing protein	A0A1B1IVR3	uncultured_Mediterranean_phage	2.0e-106	36.3

DBSCAN-SWA_4

1344573 : 1353043

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001831735.1\|1344573_1345056_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	5.2e-21	43.3
WP_001831674.1\|1345042_1346170_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_001831723.1\|1346170_1346875_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	H8ZMN3	Synechococcus_phage	1.6e-47	42.5
WP_001831728.1\|1346874_1347135_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_001831727.1\|1347136_1347808_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_002467589.1\|1347800_1349990_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.1e-139	40.4
WP_002485328.1\|1349968_1351453_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	7.2e-45	31.9
WP_001831685.1\|1351445_1352477_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	2.1e-64	43.4
WP_001831672.1\|1352476_1353043_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	6.1e-29	40.0

DBSCAN-SWA_5

2079323 : 2150729

Staphylococcus_phage(70.59%)

integrase,transposase,protease

attL 2128536:2128553|attR 2160329:2160346

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001830894.1\|2079323_2079887_+	methyltransferase domain-containing protein	A0A2H4PQV0	Staphylococcus_phage	1.9e-67	66.5
WP_001830809.1\|2080123_2080525_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_001830886.1\|2081014_2081842_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_001832688.1\|2082084_2083086_+	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	1.3e-130	69.4
WP_002456446.1\|2083342_2083804_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.2e-59	84.2
WP_002456445.1\|2083816_2084998_-	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	2.5e-178	76.1
WP_002467848.1\|2085010_2085643_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.1e-87	77.6
WP_002495598.1\|2085649_2086693_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	8.9e-135	66.8
WP_011082717.1\|2087129_2088623_-	FAD-dependent oxidoreductase	A0A2H4PQX2	Staphylococcus_phage	2.5e-13	65.6
WP_001830727.1\|2088961_2089813_-	autolysin	A0A1J0MFB0	Staphylococcus_phage	1.0e-32	35.6
WP_002456441.1\|2090190_2090406_-	hypothetical protein	NA	NA	NA	NA
WP_010959195.1\|2090438_2090558_+	hypothetical protein	NA	NA	NA	NA
WP_001830724.1\|2090613_2091093_+	sigma-70 family RNA polymerase sigma factor	A0A2H4PQT5	Staphylococcus_phage	2.7e-25	42.3
WP_001830734.1\|2091098_2091542_+	competence protein ComK	NA	NA	NA	NA
WP_002485267.1\|2091528_2091972_-	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	5.3e-20	43.5
WP_001830731.1\|2092111_2092825_-	transaldolase	M1PR54	Cyanophage	4.1e-22	37.4
WP_002446728.1\|2093101_2093410_+	hypothetical protein	NA	NA	NA	NA
WP_001830726.1\|2093448_2093814_+	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	4.1e-34	57.0
WP_001830729.1\|2093810_2094164_+	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	8.5e-05	32.5
WP_104832450.1\|2094642_2095821_+\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	5.7e-61	37.2
WP_001829826.1\|2096050_2096206_-	hypothetical protein	A0A146ICT8	Staphylococcus_phage	1.2e-14	77.6
WP_104832450.1\|2096586_2097765_-\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	5.7e-61	37.2
WP_001829832.1\|2098049_2098886_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	1.0e-120	73.3
WP_002474706.1\|2099066_2099975_-	hypothetical protein	A0A2H4PQQ8	Staphylococcus_phage	1.8e-102	80.6
WP_001829830.1\|2100077_2101277_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	4.1e-192	85.4
WP_002485319.1\|2101646_2103239_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	2.7e-268	83.2
WP_002489377.1\|2103469_2104255_-	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	2.7e-99	71.3
WP_011082720.1\|2104241_2104718_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	1.1e-44	58.7
WP_001829824.1\|2104776_2105028_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	1.9e-35	81.9
WP_002485317.1\|2105024_2106026_-	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	9.0e-92	50.5
WP_002485320.1\|2106015_2107440_-	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	1.1e-172	63.7
WP_002485101.1\|2108451_2108598_+	hypothetical protein	NA	NA	NA	NA
WP_002485100.1\|2108692_2109358_+	hypothetical protein	A0A2H4J5B8	uncultured_Caudovirales_phage	2.7e-07	37.6
WP_002485103.1\|2109729_2110062_+\|integrase	integrase	A0A2H4JGN1	uncultured_Caudovirales_phage	6.5e-31	65.4
WP_002456425.1\|2110097_2110253_+	hypothetical protein	NA	NA	NA	NA
WP_002456424.1\|2110334_2111069_+	hypothetical protein	NA	NA	NA	NA
WP_002485104.1\|2111334_2111661_-	amidase	A0A2H4JCA1	uncultured_Caudovirales_phage	7.1e-38	74.1
WP_011082722.1\|2111820_2112315_+\|integrase	site-specific integrase	B7T092	Staphylococcus_virus	9.9e-68	76.1
WP_011082723.1\|2112289_2112382_+	hypothetical protein	NA	NA	NA	NA
WP_002484853.1\|2112627_2113188_-	hypothetical protein	NA	NA	NA	NA
WP_002505786.1\|2113174_2114548_-	ATP-binding protein	V9QJ85	Oenococcus_phage	1.5e-52	31.9
WP_002484614.1\|2114848_2115763_+	DUF4238 domain-containing protein	NA	NA	NA	NA
WP_002505510.1\|2115957_2116785_-	hypothetical protein	NA	NA	NA	NA
WP_002484931.1\|2116975_2119312_-	DUF3991 domain-containing protein	NA	NA	NA	NA
WP_002484406.1\|2119377_2119590_-	hypothetical protein	NA	NA	NA	NA
WP_002484408.1\|2119665_2120427_-	class A sortase	NA	NA	NA	NA
WP_011082726.1\|2120437_2120917_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_002484399.1\|2120885_2123042_-	type IA DNA topoisomerase	A0A1X9I6W8	Streptococcus_phage	2.3e-76	38.1
WP_002484400.1\|2123083_2124388_-	hypothetical protein	NA	NA	NA	NA
WP_002484396.1\|2124392_2124743_-	hypothetical protein	NA	NA	NA	NA
WP_011082727.1\|2124739_2125060_-	hypothetical protein	NA	NA	NA	NA
WP_011082728.1\|2125115_2125235_-	hypothetical protein	NA	NA	NA	NA
WP_002484407.1\|2125265_2126123_-	hypothetical protein	NA	NA	NA	NA
WP_002484410.1\|2126119_2126722_-	hypothetical protein	NA	NA	NA	NA
WP_002484401.1\|2126742_2127813_-	CHAP domain-containing protein	A0A249Y1A9	Staphylococcus_phage	2.0e-33	58.0
WP_002484404.1\|2127816_2129766_-	ATP-binding protein	NA	NA	NA	NA
2128536:2128553	attL	NA	NA	NA	NA
WP_011082729.1\|2129791_2130388_-	hypothetical protein	NA	NA	NA	NA
WP_002484394.1\|2130393_2130720_-	hypothetical protein	NA	NA	NA	NA
WP_002484393.1\|2130766_2131168_-	hypothetical protein	NA	NA	NA	NA
WP_002484397.1\|2131167_2133465_-	hypothetical protein	NA	NA	NA	NA
WP_002505512.1\|2133461_2136041_-	type IV secretory system conjugative DNA transfer family protein	NA	NA	NA	NA
WP_002484402.1\|2136040_2136733_-	hypothetical protein	NA	NA	NA	NA
WP_002484415.1\|2136733_2138980_-	hypothetical protein	NA	NA	NA	NA
WP_002484412.1\|2139049_2139352_-	hypothetical protein	NA	NA	NA	NA
WP_011082730.1\|2139468_2139738_-	hypothetical protein	NA	NA	NA	NA
WP_002505516.1\|2139738_2142777_-	isopeptide-forming domain-containing fimbrial protein	NA	NA	NA	NA
WP_011082731.1\|2142793_2144041_-	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_011082732.1\|2144151_2145042_+	hypothetical protein	NA	NA	NA	NA
WP_011082733.1\|2145081_2145342_-	hypothetical protein	NA	NA	NA	NA
WP_002484694.1\|2145346_2145772_-	hypothetical protein	NA	NA	NA	NA
WP_002484696.1\|2145743_2146193_-	hypothetical protein	A0A097PBE7	Streptococcus_pyogenes_phage	5.4e-12	40.4
WP_011082734.1\|2146189_2146636_-	DUF771 domain-containing protein	NA	NA	NA	NA
WP_002484687.1\|2147913_2148450_-	hypothetical protein	NA	NA	NA	NA
WP_002484689.1\|2148482_2148683_-	hypothetical protein	NA	NA	NA	NA
WP_011082735.1\|2149649_2150729_+\|integrase	site-specific integrase	A0A1J0MFS3	Staphylococcus_phage	1.6e-70	42.1
2160329:2160346	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP043845

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection