CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	4 crisprs	RT,WYL,csx3,csx1,cas10,csm3gr7,csx10gr5,csx19,c2c9_V-U4,cas14j,cas3,cas8a4,cas7,cas5,cas6,cas4,cas1,cas2	1	93	1	0
NZ_CP046712	Nostoc sp. ATCC 53789 plasmid pNsp_i, complete sequence	0 crisprs	NA	0	0	0	0
NZ_CP046713	Nostoc sp. ATCC 53789 plasmid pNsp_j, complete sequence	0 crisprs	NA	0	0	0	0
NZ_CP046711	Nostoc sp. ATCC 53789 plasmid pNsp_h, complete sequence	1 crisprs	NA	0	1	0	0
NZ_CP046703	Nostoc sp. ATCC 53789 chromosome, complete genome	18 crisprs	cas14k,cas14j,csa3,RT,DEDDh,PD-DExK,cas3,DinG,Cas14c_CAS-V-F,WYL,cas10d,csc2gr7,csc1gr5,2OG_CAS,cas6,cas4,cas1,cas2,Cas14u_CAS-V	1	14	7	0
NZ_CP046707	Nostoc sp. ATCC 53789 plasmid pNsp_d, complete sequence	1 crisprs	NA	0	1	0	0
NZ_CP046715	Nostoc sp. ATCC 53789 plasmid pNsp_l, complete sequence	1 crisprs	NA	1	1	0	0
NZ_CP046714	Nostoc sp. ATCC 53789 plasmid pNsp_k, complete sequence	0 crisprs	NA	0	0	0	0
NZ_CP046706	Nostoc sp. ATCC 53789 plasmid pNsp_c, complete sequence	1 crisprs	c2c9_V-U4	0	1	0	0
NZ_CP046709	Nostoc sp. ATCC 53789 plasmid pNsp_f, complete sequence	1 crisprs	NA	1	1	0	0
NZ_CP046710	Nostoc sp. ATCC 53789 plasmid pNsp_g, complete sequence	1 crisprs	NA	1	1	0	0
NZ_CP046708	Nostoc sp. ATCC 53789 plasmid pNsp_e, complete sequence	1 crisprs	NA	0	1	0	0
NZ_CP046705	Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence	3 crisprs	RT,cas14j,cas14k	3	4	3	1

1. NZ_CP046707

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP046707_1

• CRISPR_ID: NZ_CP046707_1
• CRISPR_location: 4883-4994
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP046707_1

Consensus_repeat	Method
GGCTTAGTCTAGGCTTAGTCCAAGCTTAGTTTAGG	CRISPRCasFinder

spacers of NZ_CP046707_1

>1.1|4918|42|NZ_CP046707|CRISPRCasFinder
CTTAGTTTAGGAAACTTGCTTTCTTGAAAAACTGATTCCCTG

CRISPR arrays and Neighbor proteins around NZ_CP046707_1

CRISPR arrays

The CRISPR arrays of NZ_CP046707_1

>merge|NZ_CP046707|1|4883-4994|CRISPRCasFinder
CGCTAAGTTGTGGCTTAGTCTAGGCTTAGTCCAAGCTTAGTTTAGGAAACTTGCTTTCTTGAAAAACTGATTCCCTGTGCTTAGTCTAGGCTTAGTCTAGGCTTAGTCCAAG

>NZ_CP046707|1|1|4883-4994|CRISPRCasFinder
CGCTAAGTTGTGGCTTAGTCTAGGCTTAGTCCAAG	CTTAGTTTAGGAAACTTGCTTTCTTGAAAAACTGATTCCCTG
TGCTTAGTCTAGGCTTAGTCTAGGCTTAGTCCAAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046707.1|WP_147262554.1|9935_10325_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046707.1|WP_147262466.1|254_488_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046707.1|WP_159402681.1|996_1158_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046707.1|WP_114084202.1|6959_7412_+|Hsp20/alpha-crystallin-family-protein	unknown	unknown	gnl|CDD|223149
NZ_CP046707.1|WP_114084197.1|9224_9671_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046707.1|WP_114084201.1|7583_8087_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046707.1|WP_114084198.1|8918_9119_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046707.1|WP_114084209.1|5908_6394_+|GIY-YIG-nuclease-family-protein	unknown	unknown	unknown
NZ_CP046707.1|WP_159402682.1|2103_2280_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046707.1|WP_159402680.1|720_864_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046707.1|WP_114081115.1|1177_1609_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046707.1|WP_114084199.1|8425_8896_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046707.1|WP_114084203.1|6414_6618_+|hypothetical-protein	unknown	unknown	gnl|CDD|376468
NZ_CP046707.1|WP_114084200.1|8124_8421_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046707.1|WP_159402684.1|4391_4553_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046707.1|WP_159402683.1|2548_2707_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046707.1|WP_114084204.1|5113_5656_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046707.1|WP_114084203.1|6414_6618_+|hypothetical-protein	gnl|CDD|376468	pfam01155, HypA, Hydrogenase/urease nickel incorporation, metallochaperone, hypA. HypA is a metallochaperone that binds nickel to bring it safely to its target. The targets for Hypa are the nickel-containing enzymes [Ni,Fe]-hydrogenase and urease. The nickel coordinates with four nitrogens within the protein. The four conserved cysteines towards the C-terminus bind one zinc moiety probably to stabilize the protein fold.	0.00737317
NZ_CP046707.1|WP_114084202.1|6959_7412_+|Hsp20/alpha-crystallin-family-protein	gnl|CDD|223149	COG0071, IbpA, Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones].	7.12166e-32

Protein sequences

>NZ_CP046707.1|WP_159402684.1|4391_4553_+|hypothetical-protein
MPAVLASRTTFFDLCLIPEAIAIGSYSPTADSHPSSSTAFAIGHWMLRKRRCP
>NZ_CP046707.1|WP_159402683.1|2548_2707_-|hypothetical-protein
MSPLTILRIEKLKTFGNVAASDDHVTRNRETPNADPTRDNRRLIEGEDSRDC
>NZ_CP046707.1|WP_159402682.1|2103_2280_+|hypothetical-protein
MIFDWQLRCLPDGGVAASPHWHNRATISILYCFANAGFYTKLVVTTEKSGILYQVLIP
>NZ_CP046707.1|WP_114081115.1|1177_1609_-|hypothetical-protein
MTDRIDQIIEKLQQLKEIRQHLVNEPMSESGVWIHQYEVRKKYKKDGEIYWYVYAKWQANEPIFKRNPKARLKGIVKRGKNPEYTCHQHIGRVGSSTGLGTDPEVTEAYREWENRKQLDAIDKALEEIENALIGVMPENNDKA
>NZ_CP046707.1|WP_159402681.1|996_1158_-|hypothetical-protein
MMPRAHHPMPNAQCPMLTTLKIDWRLWGFGGHGLVVMMINIYIYRERDYGIRT
>NZ_CP046707.1|WP_159402680.1|720_864_-|hypothetical-protein
MPVQGYSLGRIASSPWDGQRQGQQLKKRSRCDRHGTSSTNHRNHQGH
>NZ_CP046707.1|WP_147262466.1|254_488_+|hypothetical-protein
MLTDYSFLTACVPLVRKEAASIDCSGIMDWQLRCRATAALPRLVLWVGDRFHRAVTPSLSQSLRKADHPVIVFARKI
>NZ_CP046707.1|WP_114084204.1|5113_5656_-|hypothetical-protein
MSATHLPQTVTLNITELDSWLEKKVIEVVNKVTHGGAIAPATTATPAKVTPIKEEIDWQAKTDAEVWGSKATLAAVEKIRRSYQAICLYNDTVATGEGDRLAVTNQALRDLSGCNGLVIRDWIEQHKDEIISHNAKFGMENKKDPSNPASYANKGKDTDKILLLINEEFLSGEGFKSGRN
>NZ_CP046707.1|WP_114084209.1|5908_6394_+|GIY-YIG-nuclease-family-protein
MSADALLKWKTQILDYQQRVRETKPVQQATLFDIAPNHCDPDRIDPFTLHLQPMAFYRMPDDFGQAALYFVIDSAASLLLYIGETCRSNKRWRGTHGCKDYISSYRDLHYRYQIETAVNIGFWWDAPVERRARQALELSLIQKWRSPFNKENWERWGQPFK
>NZ_CP046707.1|WP_114084203.1|6414_6618_+|hypothetical-protein
MSDNLPFQNPDQLQQWHQGIKNANRNNIFCHCRACDYEWMDSAFDVTCIKCSSKDVESISSWQFPDD
>NZ_CP046707.1|WP_114084202.1|6959_7412_+|Hsp20/alpha-crystallin-family-protein
MALVRYNPWQDLNALERHINGLFGDTRVPSAQFDRDFIKVPAAELQENDDAIHLKLELPGLEAKDLDIQVTQDAVHISGERKSQTKTENNGTTRSEFYYGKFQRVIPLSAKVQNTNVTADYKDGILNLTLPKTEQEKNKVVKVNLEQSAA
>NZ_CP046707.1|WP_114084201.1|7583_8087_-|hypothetical-protein
MMNNLDRLLTILKEQADLIDQLNTRSNFQYKSTQRLVLEHGQPFVTKVKSPFKGELKACFENCLKGLLRYPNLNYCEGFAISEDIDIAVSHAWLINNDGELIDPTWIGERFKGSAYFGVVFTDDFVREIAQKTKCYGILDNDFMNEHQLLREGFPPHALLTEAIDAQ
>NZ_CP046707.1|WP_114084200.1|8124_8421_-|hypothetical-protein
MKAEDLKNLIISIIQEKPRFFDHVCTKDIKALLLEHYNISVTEKMIIKVMMQVVEEGVGKFGGDGYECGDGSTLTWADEHAVAGSKLTGVHKYWWFNI
>NZ_CP046707.1|WP_114084199.1|8425_8896_-|hypothetical-protein
MYYGYRCYTKEDKPLGWLYTFSCDTEYAFTNTDLHWCKRWKTERGAKKHFDNYNNRWQFKSQGGYLKIEVMPEFSESKSSAKSNQQRWNEANRDALYQAQKNYNQKRPIMSFRPKAKLLEWLDEERETDDDGELETDAALLNRKLEKLKNLEQQGF
>NZ_CP046707.1|WP_114084198.1|8918_9119_-|hypothetical-protein
MLKVPTTTFKNRPELTRTLKVLEDNDLEQLLDKTKKYFAGSESPIKVILRDKKCSGSENDKELFTI
>NZ_CP046707.1|WP_114084197.1|9224_9671_-|hypothetical-protein
MNTLELKPGDKVGIFYYDSVRIGTKAEIDVIERISPTGQVTLSNGKRYTSDGKEIGAVEPSYLWTLDKIQPILEKIETLERQKEAERQAYLASPEGRRKQAVNDTVKAAIAALNQYGWYADVDGHMDVMESEIEQVITKYVSEHEPTN
>NZ_CP046707.1|WP_147262554.1|9935_10325_-|hypothetical-protein
MMKKLELQRIEAGEYLTPDGRFYIRNTYYSNGIPGRSNTSKGWLIEDKSGLTPFHNGYHRTNIKRVDTLTEAKEIIALVMDCDRKEKILRDTGWRKQENCQPPGLCWLSPYTDKLLTQSEALLELSLMS

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP046707_1	1.1|4918|42|NZ_CP046707|CRISPRCasFinder	4918-4959	42	NZ_CP046707	Nostoc sp. ATCC 53789 plasmid pNsp_d, complete sequence	4918-4959	0	1.0

1. spacer 1.1|4918|42|NZ_CP046707|CRISPRCasFinder matches to NZ_CP046707 (Nostoc sp. ATCC 53789 plasmid pNsp_d, complete sequence) position: , mismatch: 0, identity: 1.0

cttagtttaggaaacttgctttcttgaaaaactgattccctg	CRISPR spacer
cttagtttaggaaacttgctttcttgaaaaactgattccctg	Protospacer
******************************************

2. NZ_CP046704

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP046704_1

• CRISPR_ID: NZ_CP046704_1
• CRISPR_location: 40761-42637
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 25 spacers
• Cas_protein_info: RT,WYL,csx3,csx1,cas10,csm3gr7,csx10gr5

Consensus repeat of NZ_CP046704_1

Consensus_repeat	Method
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	PILER-CR
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	CRISPRCasFinder
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	CRT

spacers of NZ_CP046704_1

>1.1|40798|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
ACAGCTAGGGTGAAGAAGCTGTATGAGTTGGAAGTAA
>1.2|40872|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
CAATCCCAAAATGATTGGCATTGTACAAGCTTTC
>1.3|40943|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
CATTCAAGACATCATGCTGGGTCAATATTTGCGA
>1.4|41014|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
CGGCTAATGCTCCGATTGTATTCAAAGCTTATCCTG
>1.5|41087|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
TAGTAGATGCTACTAGCGGTAAATACATTAAGGTG
>1.6|41159|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
TTAGCTGCTCTAGCTACAACTAATTCTGCTTCAGA
>1.7|41231|38|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
ACTTGTAAGATTAGTTCCTGCACCTGAAACATCGTTAG
>1.8|41306|43|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
CGATCGCCTGCCAGTTTTAGCTGTCTCAGCCTGAAGCCCTCCC
>1.9|41386|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
GCTTATCAGGAATAACAGCAGTTCTGAATAAACTTGG
>1.10|41460|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
AGTTTATTAAAGCTACAGAGAATATGCCTATGCTGGA
>1.11|41534|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
CCTCAAAACTGGGAAGAATTTGTTAATCTCACCACA
>1.12|41607|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
AAACACACGCCGATTCTATTCGCGGAATGGCAGAAC
>1.13|41680|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
CAGAACAGCAAAGATTTACTCTGAATGACTCGGAAC
>1.14|41753|41|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
ATAAGTGGGAAAAACCAGATGAGTATAGGGAAGAATGGGTA
>1.15|41831|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
CATAGAGGCTGGGTATGTCGTTGCAAACAGTGTTGA
>1.16|41904|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
ACGATGATACACGCAAAAAGTTATTCCCCAAGTATG
>1.17|41977|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
GTTTAAAGTTGCTCTACCAATAGTGTCGTTTACGA
>1.18|42049|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
AAGCGGGGGCTAGTTACGGCTTGGAGTGGGCATTTA
>1.19|42122|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
CTTTTTGTTGTTCTGCTGACACTTGTTGAATTTTG
>1.20|42194|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
TTTACAAAAAAAACTATCTTTTAACTACTAGCGCATC
>1.21|42268|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
AACCATGAATATTCTGAAAAGAATTTAATAATCCCAT
>1.22|42342|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
ATCTTCTTCTATCTCACATATATCTTTCTCTATGTA
>1.23|42415|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
CATTTACATAACCACCCTCACGGTGTAAACGGTCTTT
>1.24|42489|38|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
CGTTTTGGACACTACAGGGATATAACTAAAAAAAGAAT
>1.25|42564|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
ACTCAAGATATGCTCATGAGGGCATTTAATGAAGAC

CRISPR arrays and Neighbor proteins around NZ_CP046704_1

CRISPR arrays

The CRISPR arrays of NZ_CP046704_1

>merge|NZ_CP046704|1|40761-42637|PILER-CR,CRISPRCasFinder,CRT
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAACACAGCTAGGGTGAAGAAGCTGTATGAGTTGGAAGTAAGTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAACCAATCCCAAAATGATTGGCATTGTACAAGCTTTCGTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAACCATTCAAGACATCATGCTGGGTCAATATTTGCGAGTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAACCGGCTAATGCTCCGATTGTATTCAAAGCTTATCCTGGTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAACTAGTAGATGCTACTAGCGGTAAATACATTAAGGTGGTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAACTTAGCTGCTCTAGCTACAACTAATTCTGCTTCAGAGTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAACACTTGTAAGATTAGTTCCTGCACCTGAAACATCGTTAGGTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAACCGATCGCCTGCCAGTTTTAGCTGTCTCAGCCTGAAGCCCTCCCGTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAACGCTTATCAGGAATAACAGCAGTTCTGAATAAACTTGGGTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAACAGTTTATTAAAGCTACAGAGAATATGCCTATGCTGGAGTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAACCCTCAAAACTGGGAAGAATTTGTTAATCTCACCACAGTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAACAAACACACGCCGATTCTATTCGCGGAATGGCAGAACGTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAACCAGAACAGCAAAGATTTACTCTGAATGACTCGGAACGTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAACATAAGTGGGAAAAACCAGATGAGTATAGGGAAGAATGGGTAGTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAACCATAGAGGCTGGGTATGTCGTTGCAAACAGTGTTGAGTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAACACGATGATACACGCAAAAAGTTATTCCCCAAGTATGGTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAACGTTTAAAGTTGCTCTACCAATAGTGTCGTTTACGAGTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAACAAGCGGGGGCTAGTTACGGCTTGGAGTGGGCATTTAGTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAACCTTTTTGTTGTTCTGCTGACACTTGTTGAATTTTGGTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAACTTTACAAAAAAAACTATCTTTTAACTACTAGCGCATCGTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAACAACCATGAATATTCTGAAAAGAATTTAATAATCCCATGTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAACATCTTCTTCTATCTCACATATATCTTTCTCTATGTAGTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAACCATTTACATAACCACCCTCACGGTGTAAACGGTCTTTGTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAACCGTTTTGGACACTACAGGGATATAACTAAAAAAAGAATGTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAACACTCAAGATATGCTCATGAGGGCATTTAATGAAGACGTTTCCAAAGCCTATTACCCCGCAAGGGGACTTAAACC

>NZ_CP046704|1|1|40761-42636|PILER-CR
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	ACAGCTAGGGTGAAGAAGCTGTATGAGTTGGAAGTAA
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	CAATCCCAAAATGATTGGCATTGTACAAGCTTTC
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	CATTCAAGACATCATGCTGGGTCAATATTTGCGA
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	CGGCTAATGCTCCGATTGTATTCAAAGCTTATCCTG
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	TAGTAGATGCTACTAGCGGTAAATACATTAAGGTG
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	TTAGCTGCTCTAGCTACAACTAATTCTGCTTCAGA
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	ACTTGTAAGATTAGTTCCTGCACCTGAAACATCGTTAG
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	CGATCGCCTGCCAGTTTTAGCTGTCTCAGCCTGAAGCCCTCCC
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	GCTTATCAGGAATAACAGCAGTTCTGAATAAACTTGG
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	AGTTTATTAAAGCTACAGAGAATATGCCTATGCTGGA
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	CCTCAAAACTGGGAAGAATTTGTTAATCTCACCACA
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	AAACACACGCCGATTCTATTCGCGGAATGGCAGAAC
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	CAGAACAGCAAAGATTTACTCTGAATGACTCGGAAC
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	ATAAGTGGGAAAAACCAGATGAGTATAGGGAAGAATGGGTA
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	CATAGAGGCTGGGTATGTCGTTGCAAACAGTGTTGA
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	ACGATGATACACGCAAAAAGTTATTCCCCAAGTATG
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	GTTTAAAGTTGCTCTACCAATAGTGTCGTTTACGA
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	AAGCGGGGGCTAGTTACGGCTTGGAGTGGGCATTTA
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	CTTTTTGTTGTTCTGCTGACACTTGTTGAATTTTG
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	TTTACAAAAAAAACTATCTTTTAACTACTAGCGCATC
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	AACCATGAATATTCTGAAAAGAATTTAATAATCCCAT
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	ATCTTCTTCTATCTCACATATATCTTTCTCTATGTA
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	CATTTACATAACCACCCTCACGGTGTAAACGGTCTTT
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	CGTTTTGGACACTACAGGGATATAACTAAAAAAAGAAT
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	ACTCAAGATATGCTCATGAGGGCATTTAATGAAGAC
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTTAAAC

>NZ_CP046704|1|1|40761-42637|CRISPRCasFinder
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	ACAGCTAGGGTGAAGAAGCTGTATGAGTTGGAAGTAA
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	CAATCCCAAAATGATTGGCATTGTACAAGCTTTC
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	CATTCAAGACATCATGCTGGGTCAATATTTGCGA
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	CGGCTAATGCTCCGATTGTATTCAAAGCTTATCCTG
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	TAGTAGATGCTACTAGCGGTAAATACATTAAGGTG
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	TTAGCTGCTCTAGCTACAACTAATTCTGCTTCAGA
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	ACTTGTAAGATTAGTTCCTGCACCTGAAACATCGTTAG
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	CGATCGCCTGCCAGTTTTAGCTGTCTCAGCCTGAAGCCCTCCC
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	GCTTATCAGGAATAACAGCAGTTCTGAATAAACTTGG
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	AGTTTATTAAAGCTACAGAGAATATGCCTATGCTGGA
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	CCTCAAAACTGGGAAGAATTTGTTAATCTCACCACA
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	AAACACACGCCGATTCTATTCGCGGAATGGCAGAAC
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	CAGAACAGCAAAGATTTACTCTGAATGACTCGGAAC
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	ATAAGTGGGAAAAACCAGATGAGTATAGGGAAGAATGGGTA
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	CATAGAGGCTGGGTATGTCGTTGCAAACAGTGTTGA
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	ACGATGATACACGCAAAAAGTTATTCCCCAAGTATG
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	GTTTAAAGTTGCTCTACCAATAGTGTCGTTTACGA
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	AAGCGGGGGCTAGTTACGGCTTGGAGTGGGCATTTA
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	CTTTTTGTTGTTCTGCTGACACTTGTTGAATTTTG
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	TTTACAAAAAAAACTATCTTTTAACTACTAGCGCATC
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	AACCATGAATATTCTGAAAAGAATTTAATAATCCCAT
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	ATCTTCTTCTATCTCACATATATCTTTCTCTATGTA
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	CATTTACATAACCACCCTCACGGTGTAAACGGTCTTT
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	CGTTTTGGACACTACAGGGATATAACTAAAAAAAGAAT
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	ACTCAAGATATGCTCATGAGGGCATTTAATGAAGAC
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTTAAACC

>NZ_CP046704|1|1|40761-42636|CRT
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	ACAGCTAGGGTGAAGAAGCTGTATGAGTTGGAAGTAA
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	CAATCCCAAAATGATTGGCATTGTACAAGCTTTC
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	CATTCAAGACATCATGCTGGGTCAATATTTGCGA
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	CGGCTAATGCTCCGATTGTATTCAAAGCTTATCCTG
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	TAGTAGATGCTACTAGCGGTAAATACATTAAGGTG
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	TTAGCTGCTCTAGCTACAACTAATTCTGCTTCAGA
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	ACTTGTAAGATTAGTTCCTGCACCTGAAACATCGTTAG
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	CGATCGCCTGCCAGTTTTAGCTGTCTCAGCCTGAAGCCCTCCC
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	GCTTATCAGGAATAACAGCAGTTCTGAATAAACTTGG
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	AGTTTATTAAAGCTACAGAGAATATGCCTATGCTGGA
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	CCTCAAAACTGGGAAGAATTTGTTAATCTCACCACA
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	AAACACACGCCGATTCTATTCGCGGAATGGCAGAAC
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	CAGAACAGCAAAGATTTACTCTGAATGACTCGGAAC
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	ATAAGTGGGAAAAACCAGATGAGTATAGGGAAGAATGGGTA
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	CATAGAGGCTGGGTATGTCGTTGCAAACAGTGTTGA
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	ACGATGATACACGCAAAAAGTTATTCCCCAAGTATG
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	GTTTAAAGTTGCTCTACCAATAGTGTCGTTTACGA
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	AAGCGGGGGCTAGTTACGGCTTGGAGTGGGCATTTA
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	CTTTTTGTTGTTCTGCTGACACTTGTTGAATTTTG
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	TTTACAAAAAAAACTATCTTTTAACTACTAGCGCATC
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	AACCATGAATATTCTGAAAAGAATTTAATAATCCCAT
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	ATCTTCTTCTATCTCACATATATCTTTCTCTATGTA
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	CATTTACATAACCACCCTCACGGTGTAAACGGTCTTT
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	CGTTTTGGACACTACAGGGATATAACTAAAAAAAGAAT
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	ACTCAAGATATGCTCATGAGGGCATTTAATGAAGAC
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTTAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046704.1|WP_114082147.1|35357_35561_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046704.1|WP_114082194.1|45367_45946_-|HD-domain-containing-protein	unknown	unknown	gnl|CDD|379122
NZ_CP046704.1|WP_114082145.1|33292_33691_-|hypothetical-protein	unknown	unknown	gnl|CDD|133390
NZ_CP046704.1|WP_114082148.1|35553_35880_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046704.1|WP_114082144.1|32837_33296_-|DUF1392-domain-containing-protein	unknown	unknown	gnl|CDD|284550
NZ_CP046704.1|WP_114082149.1|36003_36660_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046704.1|WP_114082151.1|42688_43123_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046704.1|WP_084226926.1|39166_39403_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|238045
NZ_CP046704.1|WP_114082157.1|51682_52351_+|RAMP-superfamily-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|377130
NZ_CP046704.1|WP_114082146.1|34000_34843_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046704.1|WP_114082158.1|52347_53961_+|hypothetical-protein	csx10gr5	cls000715_csx10gr5_CAS-III-D	gnl|CDD|131722
NZ_CP046704.1|WP_114082155.1|48809_50072_+|DUF1887-family-protein	csx1	mkCas0112_csx1_CAS-III	gnl|CDD|312526
NZ_CP046704.1|WP_114082152.1|43132_43372_+|isoprenylcysteine-carboxylmethyltransferase-family-protein	unknown	unknown	gnl|CDD|224931
NZ_CP046704.1|WP_114082154.1|47800_48736_+|CRISPR-associated-protein-Csx3	csx3	mkCas0115_csx3_CAS-I:CAS-III	unknown
NZ_CP046704.1|WP_114082193.1|36844_38386_-|RNA-dependent-DNA-polymerase	RT	pfam00078_RT_CAS-I:CAS-III	gnl|CDD|275209
NZ_CP046704.1|WP_114082195.1|45953_47348_-|TIGR03985-family-CRISPR-associated-protein	WYL	mkCas0075_WYL_CAS-I:CAS-III	gnl|CDD|274901
NZ_CP046704.1|WP_147262502.1|36576_36798_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046704.1|WP_114082156.1|50068_51682_+|hypothetical-protein	cas10	mkCas0133_cas10_CAS-III	gnl|CDD|187811
NZ_CP046704.1|WP_114082150.1|39554_40523_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046704.1|WP_114082153.1|47450_47756_+|CRISPR-associated-protein-Csx3	csx3	mkCas0115_csx3_CAS-I:CAS-III	gnl|CDD|187871

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP046704.1|WP_114082158.1|52347_53961_+|hypothetical-protein	csx10gr5	cls000715_csx10gr5_CAS-III-D	1.4e-58	193.6	0.0
NZ_CP046704.1|WP_114082156.1|50068_51682_+|hypothetical-protein	cas10	mkCas0133_cas10_CAS-III	4.5e-121	399.4	0.7
NZ_CP046704.1|WP_114082193.1|36844_38386_-|RNA-dependent-DNA-polymerase	RT	pfam00078_RT_CAS-I:CAS-III	4.9e-39	128.9	0.0
NZ_CP046704.1|WP_114082154.1|47800_48736_+|CRISPR-associated-protein-Csx3	csx3	mkCas0115_csx3_CAS-I:CAS-III	1.2e-101	334.2	0.0
NZ_CP046704.1|WP_114082155.1|48809_50072_+|DUF1887-family-protein	csx1	mkCas0112_csx1_CAS-III	2e-146	482.9	2.6
NZ_CP046704.1|WP_114082195.1|45953_47348_-|TIGR03985-family-CRISPR-associated-protein	WYL	mkCas0075_WYL_CAS-I:CAS-III	2.3e-169	559.0	8.7
NZ_CP046704.1|WP_114082157.1|51682_52351_+|RAMP-superfamily-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	9.9e-70	229.0	0.0
NZ_CP046704.1|WP_114082153.1|47450_47756_+|CRISPR-associated-protein-Csx3	csx3	mkCas0115_csx3_CAS-I:CAS-III	1.5e-19	64.7	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046704.1|WP_114082194.1|45367_45946_-|HD-domain-containing-protein	gnl|CDD|379122	pfam13328, HD_4, HD domain. HD domains are metal dependent phosphohydrolases.	1.61128e-32
NZ_CP046704.1|WP_114082144.1|32837_33296_-|DUF1392-domain-containing-protein	gnl|CDD|284550	pfam07154, DUF1392, Protein of unknown function (DUF1392). This family consists of several hypothetical cyanobacterial proteins of around 150 residues in length which seem to be specific to Anabaena species. The function of this family is unknown.	5.56733e-79
NZ_CP046704.1|WP_114082195.1|45953_47348_-|TIGR03985-family-CRISPR-associated-protein	gnl|CDD|274901	TIGR03985, hypothetical_protein_sll7078, CRISPR-associated protein, TIGR03985 family. Members of this protein family belong to CRISPR-associated (Cas) gene clusters. The majority of members are Cyanobacterial.	9.5435e-103
NZ_CP046704.1|WP_114082145.1|33292_33691_-|hypothetical-protein	gnl|CDD|133390	cd04762, HTH_MerR-trunc, Helix-Turn-Helix DNA binding domain of truncated MerR-like proteins. Proteins in this family mostly have a truncated helix-turn-helix (HTH) MerR-like domain. They lack a portion of the C-terminal region, called Wing 2 and the long dimerization helix that is typically present in MerR-like proteins. These truncated domains are found in response regulator receiver (REC) domain proteins (i.e., CheY), cytosine-C5 specific DNA methylases, IS607 transposase-like proteins, and RacA, a bacterial protein that anchors chromosomes to cell poles.	0.00010931
NZ_CP046704.1|WP_084226926.1|39166_39403_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	5.68951e-07
NZ_CP046704.1|WP_114082157.1|51682_52351_+|RAMP-superfamily-protein	gnl|CDD|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	8.09595e-11
NZ_CP046704.1|WP_114082158.1|52347_53961_+|hypothetical-protein	gnl|CDD|131722	TIGR02674, cas_cyan_RAMP_2, CRISPR-associated RAMP protein, Csx10 family. CRISPR is a widespread repeat family in prokaryotes. At least 45 different protein families occur in prokaryotes only when these repeats are present. This family, a minor CRISPR-associated protein family, seems largely restricted to the Cyanobacteria. It belongs to the RAMP superfamily (pfam03787).	7.30565e-47
NZ_CP046704.1|WP_114082152.1|43132_43372_+|isoprenylcysteine-carboxylmethyltransferase-family-protein	gnl|CDD|224931	COG2020, STE14, Putative protein-S-isoprenylcysteine methyltransferase [Posttranslational modification, protein turnover, chaperones].	4.98048e-14
NZ_CP046704.1|WP_114082193.1|36844_38386_-|RNA-dependent-DNA-polymerase	gnl|CDD|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	2.62573e-95
NZ_CP046704.1|WP_114082155.1|48809_50072_+|DUF1887-family-protein	gnl|CDD|312526	pfam09002, DUF1887, Domain of unknown function (DUF1887). This domain is found in a set of hypothetical bacterial proteins.	4.73519e-09
NZ_CP046704.1|WP_114082156.1|50068_51682_+|hypothetical-protein	gnl|CDD|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	0.000175767
NZ_CP046704.1|WP_114082153.1|47450_47756_+|CRISPR-associated-protein-Csx3	gnl|CDD|187871	cd09740, Csx3_III-U, CRISPR/Cas system-associated protein Csx3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small protein in some cases fused to Csx1 (COG1517) family domains.	4.64362e-05

Protein sequences

>NZ_CP046704.1|WP_114082150.1|39554_40523_+|hypothetical-protein
MPKPPSRRNKATSAASTDSTSAANSVNEDISQQEDPGSATITISAVEVPELTEEEQRDRLHLERRVERAFFEAGKALAELRDRRLYRSSHRTFEDYCRDRFAHSRQKSNYLIAAADVYENLTTICCQNLPSEDLTTNRSQILPTSEGQVRPITKLEPQEQWEVWQQAVELAGGKVPTGRIVKDVVQRIMERTQVPNTYQLGEVCQILVKDNPELRGKAGCWGIVSAVNEFSCTVRMWDGEYTIGLQHLKSYEYLPAECEQMQVICDRINRVYFDSLEETVKTLLQSLGKLNRPYLTAVEEKLLSLIEREYGLIDQSPQTHRQ
>NZ_CP046704.1|WP_084226926.1|39166_39403_+|helix-turn-helix-transcriptional-regulator
MLMDVVRQIKVTIPDLSQKIKEAREKDGRSVQVLATSAGISTAYWYQIEQEKRQWISEETLRGIEQALGLDLGVRFDD
>NZ_CP046704.1|WP_114082193.1|36844_38386_-|RNA-dependent-DNA-polymerase
MIRHSYTASESWKGMPWKKFRSTLFRLQKRIFKAVQVGDKPKARSLQKLILKSRAARYLAIRQVTQLNAGKKTAGIDGKKSLTFEERFALEELLKSNHSNWHHQGLREIPIPKKDGTTRLLKIPCISDRAWQCLAKFALEPAHEATFHARSYGFRPGRGAHDAQQYIQTNLKSSSNGINKRVIELDIEKCFDRIDHKIIMDSLISPKGLKLGIFRCLKSGVNPGFPDQGTPQGGVVSPLLANIALNGIEKIYHYKDDHYQYHEPSVRYADDMVIILRPQDNADEILAKISEFLAQRGMNVSVKKTKVTAATDGFDFLGWNFKVQKNGKLRRTPSVENFKAFRKKVKAIVNNSNYGAKVKAEKLAPLVRGWRLYHRFCKMDGSRFSLWFLNHRAYTVFNKEPKQTRHTSERLIDKAFPAVPYSEGRHVMVQGEKSPYDGNIAYWSARNSKLYNGETSFALKRQNHTCADCGLKFIDEERVHLHHIDGNHANCQKNNLEALHESCHDYRHMGKSE
>NZ_CP046704.1|WP_147262502.1|36576_36798_+|hypothetical-protein
MGLVSDVAVEFGLSEGLFVGGSRGEFLNLACLIVNNGGNPRILTAFVAYFDCTGDFAVDWLSRWVVLSTAPLI
>NZ_CP046704.1|WP_114082149.1|36003_36660_-|hypothetical-protein
MQKLTPAAPDEQALAQAELDSYIADQAQAVAPEPLTIVEISFDHHEYYADDKLIASISHDDNHLTQRWVVMVNDKEIFRANTLMRCDRFICTHYKDGSLPVQEQLATPPTTENQIMVHIFNECQNCGFEILDDGIYNDNGVKLGQVGCINGDWWVIQGYSGQQQFSNSVYDAVRSLSMADVSTDSKSIFDEYFLEQPLEQLTGNKLQRLLEKAELVTA
>NZ_CP046704.1|WP_114082148.1|35553_35880_-|hypothetical-protein
MQPIISIPQHWGYPRFALEQRTEQGTILGLYYYPSGTELAEQFDDGWRYALMPNKNSDEISYLKEDQIKPLTPEELFSEITAEIKFYQQQITILQQQLIVLTGGFTNA
>NZ_CP046704.1|WP_114082147.1|35357_35561_-|hypothetical-protein
MPKTVDPGFDRRANHLLRSIRLCGGCVPLHRLQFQFSDSVIQTLLDRELVQVQNTGRGFLLEIAEDF
>NZ_CP046704.1|WP_114082146.1|34000_34843_-|hypothetical-protein
MVTEIKLGLCNPPEPIYLFVNQGEVDGESYVWYKFNINQDKKIPVVQRALTGYLSELRLTTKEFKGKDNLKLDIVVSADELYVVRTGIETNFAKSFLLAASLIQDFSKPLIIVANAGDENTVFCNLYDAATKTKIYREWSRDLNWATIIRDIQSLLGATSNSIPEPPLTPPKLSVVPQPVHPQDLRVKNIRTLLDYPLDLVKEWLQFQDVDRPSLLDINQINELIKTMCLAWAAGKCEYPNHAESSYQNQVVDAVAKGADELTAINAWMQQLQTAKAGAV
>NZ_CP046704.1|WP_114082145.1|33292_33691_-|hypothetical-protein
MSIKWTDEELGIIEEMACLYTVKQIAYRLKRRGYTRSTSAIQNKLRFLGYSARPILDNYNCCEIARVLQLNSATVWTWVKKGWIRTTRRSGRYHQIKSKDLKRFLQNPPQRIKNRIAAIDKEKIEYLVGKLA
>NZ_CP046704.1|WP_114082144.1|32837_33296_-|DUF1392-domain-containing-protein
MIDHINTLKTIWYISPPWRETIPPIAVNLLERVFLRTTRTFGYCCGMQWKHECWIYSIDCGKEILHATQNQIIGTGELEAIKVQKPAFVLGERVILCSHDKGTKQRLILGIALVHNSWFYLVELMSPTLIKTPTISNRFSLIGEKSLVRVNA
>NZ_CP046704.1|WP_114082151.1|42688_43123_+|hypothetical-protein
MFIFKILTALIWNIVIFGGLLFLPAGTLNWWRAWVFLGVVIVGTVATMMGVFREDDDLFKERLKPPIQESQPLADKILASLLIATFLGIIGFIPLDVFRFHLFAQPSEIVSVLGLVVYVVGWWIISLSFKVNTFAATAVKHQAD
>NZ_CP046704.1|WP_114082152.1|43132_43372_+|isoprenylcysteine-carboxylmethyltransferase-family-protein
MIDTGVYGVVRHPMYAGAILVMVGMSLWLESVAASLLTIVPMTILVVRIQFEEQFLRQELKGYDSYTQKIRYKLLPYLW
>NZ_CP046704.1|WP_114082194.1|45367_45946_-|HD-domain-containing-protein
MNSLKLTERFESALIYATRLHAHQTRKISGVPYISHLLSVTALVLEAGGTQEEAIAALLHDVVEDQGGKPIREDIRQLFGETVLAIIDGCTEWDTPPKPPWQERKLQYLEKLRYALPSVRLVSLADKLHNSRSLLADCQQYGDVIWTNFSAGREKTLWFYQSLVQVYQQTGSDWMTQEIERVVNQLCQENPA
>NZ_CP046704.1|WP_114082195.1|45953_47348_-|TIGR03985-family-CRISPR-associated-protein
MSELVFQDIPDIELLQCLGHGYLKQNLVRAIRLWVWLRSLYGSEGASLYGDNQDRMVLDDSFSYADWRNVFFSSTHPKGEEIPAIHDSHCPCAKTVAEWLFSEKTGVVATHWQKLILAHTGMGESELDTLLQRRLFGVTRRSLQGDLEILAKLGWLVYKYQKYYRVSEFPPRPVTTKDQASAAKVGAYELSFMHEDLVGLAENHSQKINGVQRFFLKLDYVIPRSTLDAVDDLQYELRQLWAKTPVPPIKLTYGSARIANNVDCIVYPVCIYYVQRAVYLCAYGESPQKDTDWYNFRLDHIRSLVALEWTDPKLPLNLQQQYQQKSLPNPDDIALQMAKAWGFDFYLPSQLMLLRFDRQFCDRYVKGTERHDTFEEITYQQVQRLIQREIKQPQQQNLLKVLAKRSETDAYYQAYIRYQDNEHRDNNLVMRLRAWQPKVEVLTPWDLRQSFAADAATQFMLYHN
>NZ_CP046704.1|WP_114082153.1|47450_47756_+|CRISPR-associated-protein-Csx3
MSTYKIELKEGILRINFGEPAQNDQIVRDAAARLEEMATSGELAGGPLLKINGPISIPVAFVLAHKFAHIYGAVAFYDPKLGKYVISITHNPSYKLGDLID
>NZ_CP046704.1|WP_114082154.1|47800_48736_+|CRISPR-associated-protein-Csx3
MTTYHIRLEGDVLKVGFGKDANGDQLVRDAAARLDEMVALGELSGGKLLKIDGPASVAVSYVIAHKISQLYGAIAVFDPKIGRPGYKTFITAVSQTPAYKIGELIETDEPHKPHKTKSVLKVALCGPPQSGKSCLREGLKQAISLIEGAPYPYVITACPDGEGAWFSDAARRDPDLARKLKDEYKAKFTPEFAQKAAGWVRSANTPLNIIDVGGRITDENRVIVREATHAVILASDRGKAEVPLWKEFCRDLNIQIIANLHSDCEGKEDEIVTQSPLLTGSVHYLVRGEDVSSRPMVQALARLLVGLCGKG
>NZ_CP046704.1|WP_114082155.1|48809_50072_+|DUF1887-family-protein
MTTSEFDNNKVDHLFLLIGENPLPNYVTANLLLKKGGTPYLVHTTGTETQAKRLKNILDNKPIGLQPAQLISLGKYESDAYHIQDEIRRKIQSLKNGKIGLNYTGGTKAMAVHAYRAVFSQSHADTVFSYLDARRLEMCIDREDGERIRIKVTPELLEVKLVNLFQLHGLELKQKPTQQAQLPKLAIELANIFKEETKAKQWFDWFYKIFREQAYKNKSNGGGEWKSKISLLEVSTLLDNLPQEIISAFKEENFITPDNKLSLQQVEKTGAFKEIKHFCKWLDGLWLEHYVLEQVKNIADKQIKDYGLNFEIPIKGTRDGFEFDVAFTRGYQLFAISCSTTSKRDLCKSKLFEAYLRARQMGGDEARVALICCFNEPDTLKAEILSSTNDKKIAVFGREHLTNLSEEIANWIDQNDEDAK
>NZ_CP046704.1|WP_114082156.1|50068_51682_+|hypothetical-protein
MRKFTITVIDTSGIQGYIFSSNRLRENIGASHLVSEVTGDWVEETLGVPKNQQKEPIETSGLNVEIIYAGGGNTLIVFKSRKIAINFTRILSKRVLEEAPGINLVVAHKEFDWDEDDLYQVVKDLMEGEIDRRKNERIPSAPLLGLGVTTSCNSTQLPAIDRSNKYIQYGDDEEADSYFTSTETKQKLKAVNRANKKLQEMFADVVDGDIYQFPYRTDHLGRSKRESSYAAIVHADGNGMGKRFQKYGEDAENNRDYIQRMRDFSTSVEEAGKNALKAVVQVVVKSIQEGKVVGKLGEFQLKAKYYLPFRPLVYGGDDITFICEGRLGIELAALFLREFEKQRVADCKKLTACAGICVVKTHYHFAKAYKISEELCKEAKNLVKENKEFEPDGFSAIDWHLAASGLFGSISEIRKLEYQVSVDKKDTWNLAMRPLRLEKHSSEWRTWEGFTQVVKEFKEGENWKERHNKVMALREVLRKADENATKEFLSAYKLSQLPSFPESSGRSEQLARKGWLNNRCGYFDAIEAMEFYLELED
>NZ_CP046704.1|WP_114082157.1|51682_52351_+|RAMP-superfamily-protein
MTIYQLKIKLLSDTTFGRGDGVAGLIDQEVEHDPSGFPYLRGRTLKGLLSEECDNLIAVLPPEIRSEWENFACILFGTPGSVQGTIASMHVGDACLPDDLREAVAFQIKKKTLTTTEVLDSLTTIRRQTAINSETGIADKGSLRSFRVAIRELEFKADLLFETQPSQEILSVLGVGTLALRRIGSGRNRGRGYVRCTLHDDSGVEITQSYISLLGKIQEKSA
>NZ_CP046704.1|WP_114082158.1|52347_53961_+|hypothetical-protein
MKTITFSLHTQQPLLATSFQGDPNSDVSYNYIPGSMIRGAIIGRYMKEYHLSDLDLNDDVVKRLFFDNNTCYLNGYLLSQKKNQEKRTLPVPLSWFKDKDSQLSDNSSQITVYDFSIDEEEKPETPKSVGESFWTEEDGVTFYKEKRRINIHNRRDRKKGRSSQEEGEIFCYDAIDTGQFFQAVILCHEVDADFLKNLLQKSVDIWLGGSQSAGYGYTKISDVNCHDTWNEINIPATERINRECLTITLLSDLIVRDEWGQYAVIPPSKQHQTPAPLTKELEKFLGTLKPQSSFAGNNLVGGFNRKWGLPLPQVPVLKAGSVFVFEKISITSEQIQQLENLGIGERRIEGFGRVAVNWLEKRHFYAKQSESPKISSQPVLKLQTSQTLAAQMAERLLHQKMEHALQKQIGSQEIKGDIKSSQLSRLQMVARQALSTGDCNLALSFLNNLPSNARGQFERAKIKDQSIDKSFKQKLDEWLNNPLSSIKNQQDLIVKIADVERSITDEFAKENKLAEKYTLRLIMAVAKKATKEKRNDS

Crispr_ID: NZ_CP046704_2

• CRISPR_ID: NZ_CP046704_2
• CRISPR_location: 43770-45359
• Repeat_type: NA
• Spacer_info: 21 spacers
• Cas_protein_info: RT,WYL,csx3,csx1,cas10,csm3gr7,csx10gr5,csx19

Consensus repeat of NZ_CP046704_2

Consensus_repeat	Method
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	PILER-CR
GTTTCCAAAGCCTATTACCCCGCAAGGGGACTGAAAC	CRISPRCasFinder
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	CRT

spacers of NZ_CP046704_2

>2.1|43807|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
ATGTCATAGATTACTTCTGGTAGTGCAAAATCATGA
>2.2|43880|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
ATTGAACAGTGTCGAATTCTCTCGCACTTAGTAGGC
>2.3|43953|38|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
CTTTAGCGGCAGATATTAGTTCGCGGATATCGGCTGCG
>2.4|44028|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
TCGCTATAGAGGTAAGCGATCGCCATCTCAAAAC
>2.5|44099|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
ACAAGTAGTCCGTATACTGTTCCTGGGTCGTTTATC
>2.6|44172|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
CCACCATAATCGAGCCAATTTACATCACCGGAGG
>2.7|44243|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
TAGTGTTTACAAACAAGTTCTAGACTTATCTAGAA
>2.8|44315|39|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
TTGTTTTGGCGATGAGTTGCACAGGGCGCACCACCAACA
>2.9|44391|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
TTAAACATAATTTAATATCTCTTATAAATAATAGTGA
>2.10|44465|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
AAATAAATGCTGTTACTTTGATTTAATATATCAAC
>2.11|44537|38|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
ACTTCTGCATCCATCAGTGCAACTTGAGCAACAAAGTA
>2.12|44612|39|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
ACGCTATAGCTACTAAAGCTAAAGCTGAACAAATGGGGG
>2.13|44688|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
GTAAAGAGCTAACCAAAGCTAATTTAGTTATTCAATA
>2.14|44762|43|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
AATAAATCCTGATAGCTACTGAGTACCGCGCCTGCGCCGCTAA
>2.15|44842|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
CGAAGCTTTGGGATGACTACCTCAAAAAGCCAATCTT
>2.16|44916|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
AGGTTGATACTGTGAATAGGGCTTTTCACCGGGTAC
>2.17|44989|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
GTCGAATGTAAACAACTTAATCTGAAAATCCACTTAT
>2.18|45063|38|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
CTAGAATGCGGTTTGCTCAACCAGGCAATGACATGAAG
>2.19|45138|41|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
GAAAGAAGGGCCGTTACGAGAACTGCCAAGATAATTCCAGT
>2.20|45216|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
ATAAACTCTGCATCCTCGCTGTTATAGAACTGAG
>2.21|45287|36|NZ_CP046704|CRISPRCasFinder,CRT
TGGATGCAATCTTGAGTCATTGTGTGGTGGTTGCGT

CRISPR arrays and Neighbor proteins around NZ_CP046704_2

CRISPR arrays

The CRISPR arrays of NZ_CP046704_2

>merge|NZ_CP046704|2|43770-45359|PILER-CR,CRISPRCasFinder,CRT
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAACATGTCATAGATTACTTCTGGTAGTGCAAAATCATGAGTTTCCATTAACCAAATCCCCTCACGGGGACTGAAACATTGAACAGTGTCGAATTCTCTCGCACTTAGTAGGCGTTTCCATTAACCAAATCCCCTCACGGGGACTGAAACCTTTAGCGGCAGATATTAGTTCGCGGATATCGGCTGCGGTTTCCATTAACCAAATCCCCTCACGGGGACTGAAACTCGCTATAGAGGTAAGCGATCGCCATCTCAAAACGTTTCCATTAACCAAATCCCCTCACGGGGACTGAAACACAAGTAGTCCGTATACTGTTCCTGGGTCGTTTATCGTTTCCATTAACCAAATCCCCTCACGGGGACTGAAACCCACCATAATCGAGCCAATTTACATCACCGGAGGGTTTCCATTAACCAAATCCCCTCACGGGGACTGAAACTAGTGTTTACAAACAAGTTCTAGACTTATCTAGAAGTTTCCATTAACCAAATCCCCTCACGGGGACTGAAACTTGTTTTGGCGATGAGTTGCACAGGGCGCACCACCAACAGTTTCCATTAACCAAATCCCCTCACGGGGACTGAAACTTAAACATAATTTAATATCTCTTATAAATAATAGTGAGTTTCCATTAACCAAATCCCCTCACGGGGACTGAAACAAATAAATGCTGTTACTTTGATTTAATATATCAACGTTTCCATTAACCAAATCCCCTCACGGGGACTGAAACACTTCTGCATCCATCAGTGCAACTTGAGCAACAAAGTAGTTTCCATTAACCAAATCCCCTCACGGGGACTGAAACACGCTATAGCTACTAAAGCTAAAGCTGAACAAATGGGGGGTTTCCATTAACCAAATCCCCTCACGGGGACTGAAACGTAAAGAGCTAACCAAAGCTAATTTAGTTATTCAATAGTTTCCATTAACCAAATCCCCTCACGGGGACTGAAACAATAAATCCTGATAGCTACTGAGTACCGCGCCTGCGCCGCTAAGTTTCCATTAACCAAATCCCCTCACGGGGACTGAAACCGAAGCTTTGGGATGACTACCTCAAAAAGCCAATCTTGTTTCCATTAACCAAATCCCCTCACGGGGACTGAAACAGGTTGATACTGTGAATAGGGCTTTTCACCGGGTACGTTTCCATTAACCAAATCCCCTCACGGGGACTGAAACGTCGAATGTAAACAACTTAATCTGAAAATCCACTTATGTTTCCATTAACCAAATCCCCTCACGGGGACTGAAACCTAGAATGCGGTTTGCTCAACCAGGCAATGACATGAAGGTTTCCATTAACCAAATCCCCTCACGGGGACTGAAACGAAAGAAGGGCCGTTACGAGAACTGCCAAGATAATTCCAGTGTTTCCATTAACCAAATCCCCTCACGGGGACTGAAACATAAACTCTGCATCCTCGCTGTTATAGAACTGAGGTTTCCAATAACCAAATCCCCTCATGGGGACTGAAACTGGATGCAATCTTGAGTCATTGTGTGGTGGTTGCGTGTTTCCAAAGACTATTACCCCGCAAGGGGATTAAAAA

>NZ_CP046704|2|2|43770-45286|PILER-CR
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	ATGTCATAGATTACTTCTGGTAGTGCAAAATCATGA
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	ATTGAACAGTGTCGAATTCTCTCGCACTTAGTAGGC
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	CTTTAGCGGCAGATATTAGTTCGCGGATATCGGCTGCG
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	TCGCTATAGAGGTAAGCGATCGCCATCTCAAAAC
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	ACAAGTAGTCCGTATACTGTTCCTGGGTCGTTTATC
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	CCACCATAATCGAGCCAATTTACATCACCGGAGG
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	TAGTGTTTACAAACAAGTTCTAGACTTATCTAGAA
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	TTGTTTTGGCGATGAGTTGCACAGGGCGCACCACCAACA
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	TTAAACATAATTTAATATCTCTTATAAATAATAGTGA
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	AAATAAATGCTGTTACTTTGATTTAATATATCAAC
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	ACTTCTGCATCCATCAGTGCAACTTGAGCAACAAAGTA
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	ACGCTATAGCTACTAAAGCTAAAGCTGAACAAATGGGGG
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	GTAAAGAGCTAACCAAAGCTAATTTAGTTATTCAATA
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	AATAAATCCTGATAGCTACTGAGTACCGCGCCTGCGCCGCTAA
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	CGAAGCTTTGGGATGACTACCTCAAAAAGCCAATCTT
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	AGGTTGATACTGTGAATAGGGCTTTTCACCGGGTAC
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	GTCGAATGTAAACAACTTAATCTGAAAATCCACTTAT
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	CTAGAATGCGGTTTGCTCAACCAGGCAATGACATGAAG
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	GAAAGAAGGGCCGTTACGAGAACTGCCAAGATAATTCCAGT
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	ATAAACTCTGCATCCTCGCTGTTATAGAACTGAG
GTTTCCAATAACCAAATCCCCTCATGGGGACTGAAAC

>NZ_CP046704|2|2|43770-45359|CRISPRCasFinder
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	ATGTCATAGATTACTTCTGGTAGTGCAAAATCATGA
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	ATTGAACAGTGTCGAATTCTCTCGCACTTAGTAGGC
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	CTTTAGCGGCAGATATTAGTTCGCGGATATCGGCTGCG
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	TCGCTATAGAGGTAAGCGATCGCCATCTCAAAAC
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	ACAAGTAGTCCGTATACTGTTCCTGGGTCGTTTATC
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	CCACCATAATCGAGCCAATTTACATCACCGGAGG
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	TAGTGTTTACAAACAAGTTCTAGACTTATCTAGAA
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	TTGTTTTGGCGATGAGTTGCACAGGGCGCACCACCAACA
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	TTAAACATAATTTAATATCTCTTATAAATAATAGTGA
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	AAATAAATGCTGTTACTTTGATTTAATATATCAAC
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	ACTTCTGCATCCATCAGTGCAACTTGAGCAACAAAGTA
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	ACGCTATAGCTACTAAAGCTAAAGCTGAACAAATGGGGG
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	GTAAAGAGCTAACCAAAGCTAATTTAGTTATTCAATA
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	AATAAATCCTGATAGCTACTGAGTACCGCGCCTGCGCCGCTAA
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	CGAAGCTTTGGGATGACTACCTCAAAAAGCCAATCTT
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	AGGTTGATACTGTGAATAGGGCTTTTCACCGGGTAC
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	GTCGAATGTAAACAACTTAATCTGAAAATCCACTTAT
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	CTAGAATGCGGTTTGCTCAACCAGGCAATGACATGAAG
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	GAAAGAAGGGCCGTTACGAGAACTGCCAAGATAATTCCAGT
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	ATAAACTCTGCATCCTCGCTGTTATAGAACTGAG
GTTTCCAATAACCAAATCCCCTCATGGGGACTGAAAC	TGGATGCAATCTTGAGTCATTGTGTGGTGGTTGCGT
GTTTCCAAAGACTATTACCCCGCAAGGGGATTAAAAA

>NZ_CP046704|2|2|43770-45359|CRT
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	ATGTCATAGATTACTTCTGGTAGTGCAAAATCATGA
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	ATTGAACAGTGTCGAATTCTCTCGCACTTAGTAGGC
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	CTTTAGCGGCAGATATTAGTTCGCGGATATCGGCTGCG
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	TCGCTATAGAGGTAAGCGATCGCCATCTCAAAAC
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	ACAAGTAGTCCGTATACTGTTCCTGGGTCGTTTATC
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	CCACCATAATCGAGCCAATTTACATCACCGGAGG
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	TAGTGTTTACAAACAAGTTCTAGACTTATCTAGAA
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	TTGTTTTGGCGATGAGTTGCACAGGGCGCACCACCAACA
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	TTAAACATAATTTAATATCTCTTATAAATAATAGTGA
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	AAATAAATGCTGTTACTTTGATTTAATATATCAAC
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	ACTTCTGCATCCATCAGTGCAACTTGAGCAACAAAGTA
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	ACGCTATAGCTACTAAAGCTAAAGCTGAACAAATGGGGG
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	GTAAAGAGCTAACCAAAGCTAATTTAGTTATTCAATA
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	AATAAATCCTGATAGCTACTGAGTACCGCGCCTGCGCCGCTAA
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	CGAAGCTTTGGGATGACTACCTCAAAAAGCCAATCTT
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	AGGTTGATACTGTGAATAGGGCTTTTCACCGGGTAC
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	GTCGAATGTAAACAACTTAATCTGAAAATCCACTTAT
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	CTAGAATGCGGTTTGCTCAACCAGGCAATGACATGAAG
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	GAAAGAAGGGCCGTTACGAGAACTGCCAAGATAATTCCAGT
GTTTCCATTAACCAAATCCCCTCACGGGGACTGAAAC	ATAAACTCTGCATCCTCGCTGTTATAGAACTGAG
GTTTCCAATAACCAAATCCCCTCATGGGGACTGAAAC	TGGATGCAATCTTGAGTCATTGTGTGGTGGTTGCGT
GTTTCCAAAGACTATTACCCCGCAAGGGGATTAAAAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046704.1|WP_114082147.1|35357_35561_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046704.1|WP_114082160.1|55368_55932_+|TIGR03984-family-CRISPR-associated-protein	csx19	cls001376_csx19_CAS-III-D	gnl|CDD|274900
NZ_CP046704.1|WP_114082148.1|35553_35880_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046704.1|WP_114082194.1|45367_45946_-|HD-domain-containing-protein	unknown	unknown	gnl|CDD|379122
NZ_CP046704.1|WP_084226926.1|39166_39403_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|238045
NZ_CP046704.1|WP_114082151.1|42688_43123_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046704.1|WP_114082149.1|36003_36660_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046704.1|WP_114082157.1|51682_52351_+|RAMP-superfamily-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|377130
NZ_CP046704.1|WP_114082146.1|34000_34843_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046704.1|WP_114082158.1|52347_53961_+|hypothetical-protein	csx10gr5	cls000715_csx10gr5_CAS-III-D	gnl|CDD|131722
NZ_CP046704.1|WP_114082155.1|48809_50072_+|DUF1887-family-protein	csx1	mkCas0112_csx1_CAS-III	gnl|CDD|312526
NZ_CP046704.1|WP_114082152.1|43132_43372_+|isoprenylcysteine-carboxylmethyltransferase-family-protein	unknown	unknown	gnl|CDD|224931
NZ_CP046704.1|WP_114082154.1|47800_48736_+|CRISPR-associated-protein-Csx3	csx3	mkCas0115_csx3_CAS-I:CAS-III	unknown
NZ_CP046704.1|WP_114082193.1|36844_38386_-|RNA-dependent-DNA-polymerase	RT	pfam00078_RT_CAS-I:CAS-III	gnl|CDD|275209
NZ_CP046704.1|WP_114082195.1|45953_47348_-|TIGR03985-family-CRISPR-associated-protein	WYL	mkCas0075_WYL_CAS-I:CAS-III	gnl|CDD|274901
NZ_CP046704.1|WP_147262502.1|36576_36798_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046704.1|WP_114082156.1|50068_51682_+|hypothetical-protein	cas10	mkCas0133_cas10_CAS-III	gnl|CDD|187811
NZ_CP046704.1|WP_114082159.1|53950_55372_+|hypothetical-protein	csm3gr7	cd09683_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|187814
NZ_CP046704.1|WP_114082150.1|39554_40523_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046704.1|WP_114082153.1|47450_47756_+|CRISPR-associated-protein-Csx3	csx3	mkCas0115_csx3_CAS-I:CAS-III	gnl|CDD|187871

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP046704.1|WP_114082158.1|52347_53961_+|hypothetical-protein	csx10gr5	cls000715_csx10gr5_CAS-III-D	1.4e-58	193.6	0.0
NZ_CP046704.1|WP_114082160.1|55368_55932_+|TIGR03984-family-CRISPR-associated-protein	csx19	cls001376_csx19_CAS-III-D	1.5e-40	133.5	0.1
NZ_CP046704.1|WP_114082156.1|50068_51682_+|hypothetical-protein	cas10	mkCas0133_cas10_CAS-III	4.5e-121	399.4	0.7
NZ_CP046704.1|WP_114082193.1|36844_38386_-|RNA-dependent-DNA-polymerase	RT	pfam00078_RT_CAS-I:CAS-III	4.9e-39	128.9	0.0
NZ_CP046704.1|WP_114082154.1|47800_48736_+|CRISPR-associated-protein-Csx3	csx3	mkCas0115_csx3_CAS-I:CAS-III	1.2e-101	334.2	0.0
NZ_CP046704.1|WP_114082155.1|48809_50072_+|DUF1887-family-protein	csx1	mkCas0112_csx1_CAS-III	2e-146	482.9	2.6
NZ_CP046704.1|WP_114082195.1|45953_47348_-|TIGR03985-family-CRISPR-associated-protein	WYL	mkCas0075_WYL_CAS-I:CAS-III	2.3e-169	559.0	8.7
NZ_CP046704.1|WP_114082159.1|53950_55372_+|hypothetical-protein	csm3gr7	cd09683_csm3gr7_CAS-III-A:CAS-III-D	4.4e-36	119.1	0.3
NZ_CP046704.1|WP_114082157.1|51682_52351_+|RAMP-superfamily-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	9.9e-70	229.0	0.0
NZ_CP046704.1|WP_114082153.1|47450_47756_+|CRISPR-associated-protein-Csx3	csx3	mkCas0115_csx3_CAS-I:CAS-III	1.5e-19	64.7	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046704.1|WP_114082194.1|45367_45946_-|HD-domain-containing-protein	gnl|CDD|379122	pfam13328, HD_4, HD domain. HD domains are metal dependent phosphohydrolases.	1.61128e-32
NZ_CP046704.1|WP_114082160.1|55368_55932_+|TIGR03984-family-CRISPR-associated-protein	gnl|CDD|274900	TIGR03984, hypothetical_protein_FrEUN1fDRAFT_5778, CRISPR-associated protein, TIGR03984 family. Members of this protein family are found exclusively in CRISPR-containing organisms, in operon contexts with RAMP (repeat-associated mystery protein) proteins also linked to CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats).	2.16178e-38
NZ_CP046704.1|WP_114082195.1|45953_47348_-|TIGR03985-family-CRISPR-associated-protein	gnl|CDD|274901	TIGR03985, hypothetical_protein_sll7078, CRISPR-associated protein, TIGR03985 family. Members of this protein family belong to CRISPR-associated (Cas) gene clusters. The majority of members are Cyanobacterial.	9.5435e-103
NZ_CP046704.1|WP_084226926.1|39166_39403_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	5.68951e-07
NZ_CP046704.1|WP_114082157.1|51682_52351_+|RAMP-superfamily-protein	gnl|CDD|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	8.09595e-11
NZ_CP046704.1|WP_114082158.1|52347_53961_+|hypothetical-protein	gnl|CDD|131722	TIGR02674, cas_cyan_RAMP_2, CRISPR-associated RAMP protein, Csx10 family. CRISPR is a widespread repeat family in prokaryotes. At least 45 different protein families occur in prokaryotes only when these repeats are present. This family, a minor CRISPR-associated protein family, seems largely restricted to the Cyanobacteria. It belongs to the RAMP superfamily (pfam03787).	7.30565e-47
NZ_CP046704.1|WP_114082152.1|43132_43372_+|isoprenylcysteine-carboxylmethyltransferase-family-protein	gnl|CDD|224931	COG2020, STE14, Putative protein-S-isoprenylcysteine methyltransferase [Posttranslational modification, protein turnover, chaperones].	4.98048e-14
NZ_CP046704.1|WP_114082193.1|36844_38386_-|RNA-dependent-DNA-polymerase	gnl|CDD|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	2.62573e-95
NZ_CP046704.1|WP_114082155.1|48809_50072_+|DUF1887-family-protein	gnl|CDD|312526	pfam09002, DUF1887, Domain of unknown function (DUF1887). This domain is found in a set of hypothetical bacterial proteins.	4.73519e-09
NZ_CP046704.1|WP_114082156.1|50068_51682_+|hypothetical-protein	gnl|CDD|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	0.000175767
NZ_CP046704.1|WP_114082159.1|53950_55372_+|hypothetical-protein	gnl|CDD|187814	cd09683, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	1.56177e-13
NZ_CP046704.1|WP_114082153.1|47450_47756_+|CRISPR-associated-protein-Csx3	gnl|CDD|187871	cd09740, Csx3_III-U, CRISPR/Cas system-associated protein Csx3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small protein in some cases fused to Csx1 (COG1517) family domains.	4.64362e-05

Protein sequences

>NZ_CP046704.1|WP_114082152.1|43132_43372_+|isoprenylcysteine-carboxylmethyltransferase-family-protein
MIDTGVYGVVRHPMYAGAILVMVGMSLWLESVAASLLTIVPMTILVVRIQFEEQFLRQELKGYDSYTQKIRYKLLPYLW
>NZ_CP046704.1|WP_114082151.1|42688_43123_+|hypothetical-protein
MFIFKILTALIWNIVIFGGLLFLPAGTLNWWRAWVFLGVVIVGTVATMMGVFREDDDLFKERLKPPIQESQPLADKILASLLIATFLGIIGFIPLDVFRFHLFAQPSEIVSVLGLVVYVVGWWIISLSFKVNTFAATAVKHQAD
>NZ_CP046704.1|WP_114082150.1|39554_40523_+|hypothetical-protein
MPKPPSRRNKATSAASTDSTSAANSVNEDISQQEDPGSATITISAVEVPELTEEEQRDRLHLERRVERAFFEAGKALAELRDRRLYRSSHRTFEDYCRDRFAHSRQKSNYLIAAADVYENLTTICCQNLPSEDLTTNRSQILPTSEGQVRPITKLEPQEQWEVWQQAVELAGGKVPTGRIVKDVVQRIMERTQVPNTYQLGEVCQILVKDNPELRGKAGCWGIVSAVNEFSCTVRMWDGEYTIGLQHLKSYEYLPAECEQMQVICDRINRVYFDSLEETVKTLLQSLGKLNRPYLTAVEEKLLSLIEREYGLIDQSPQTHRQ
>NZ_CP046704.1|WP_084226926.1|39166_39403_+|helix-turn-helix-transcriptional-regulator
MLMDVVRQIKVTIPDLSQKIKEAREKDGRSVQVLATSAGISTAYWYQIEQEKRQWISEETLRGIEQALGLDLGVRFDD
>NZ_CP046704.1|WP_114082193.1|36844_38386_-|RNA-dependent-DNA-polymerase
MIRHSYTASESWKGMPWKKFRSTLFRLQKRIFKAVQVGDKPKARSLQKLILKSRAARYLAIRQVTQLNAGKKTAGIDGKKSLTFEERFALEELLKSNHSNWHHQGLREIPIPKKDGTTRLLKIPCISDRAWQCLAKFALEPAHEATFHARSYGFRPGRGAHDAQQYIQTNLKSSSNGINKRVIELDIEKCFDRIDHKIIMDSLISPKGLKLGIFRCLKSGVNPGFPDQGTPQGGVVSPLLANIALNGIEKIYHYKDDHYQYHEPSVRYADDMVIILRPQDNADEILAKISEFLAQRGMNVSVKKTKVTAATDGFDFLGWNFKVQKNGKLRRTPSVENFKAFRKKVKAIVNNSNYGAKVKAEKLAPLVRGWRLYHRFCKMDGSRFSLWFLNHRAYTVFNKEPKQTRHTSERLIDKAFPAVPYSEGRHVMVQGEKSPYDGNIAYWSARNSKLYNGETSFALKRQNHTCADCGLKFIDEERVHLHHIDGNHANCQKNNLEALHESCHDYRHMGKSE
>NZ_CP046704.1|WP_147262502.1|36576_36798_+|hypothetical-protein
MGLVSDVAVEFGLSEGLFVGGSRGEFLNLACLIVNNGGNPRILTAFVAYFDCTGDFAVDWLSRWVVLSTAPLI
>NZ_CP046704.1|WP_114082149.1|36003_36660_-|hypothetical-protein
MQKLTPAAPDEQALAQAELDSYIADQAQAVAPEPLTIVEISFDHHEYYADDKLIASISHDDNHLTQRWVVMVNDKEIFRANTLMRCDRFICTHYKDGSLPVQEQLATPPTTENQIMVHIFNECQNCGFEILDDGIYNDNGVKLGQVGCINGDWWVIQGYSGQQQFSNSVYDAVRSLSMADVSTDSKSIFDEYFLEQPLEQLTGNKLQRLLEKAELVTA
>NZ_CP046704.1|WP_114082148.1|35553_35880_-|hypothetical-protein
MQPIISIPQHWGYPRFALEQRTEQGTILGLYYYPSGTELAEQFDDGWRYALMPNKNSDEISYLKEDQIKPLTPEELFSEITAEIKFYQQQITILQQQLIVLTGGFTNA
>NZ_CP046704.1|WP_114082147.1|35357_35561_-|hypothetical-protein
MPKTVDPGFDRRANHLLRSIRLCGGCVPLHRLQFQFSDSVIQTLLDRELVQVQNTGRGFLLEIAEDF
>NZ_CP046704.1|WP_114082146.1|34000_34843_-|hypothetical-protein
MVTEIKLGLCNPPEPIYLFVNQGEVDGESYVWYKFNINQDKKIPVVQRALTGYLSELRLTTKEFKGKDNLKLDIVVSADELYVVRTGIETNFAKSFLLAASLIQDFSKPLIIVANAGDENTVFCNLYDAATKTKIYREWSRDLNWATIIRDIQSLLGATSNSIPEPPLTPPKLSVVPQPVHPQDLRVKNIRTLLDYPLDLVKEWLQFQDVDRPSLLDINQINELIKTMCLAWAAGKCEYPNHAESSYQNQVVDAVAKGADELTAINAWMQQLQTAKAGAV
>NZ_CP046704.1|WP_114082194.1|45367_45946_-|HD-domain-containing-protein
MNSLKLTERFESALIYATRLHAHQTRKISGVPYISHLLSVTALVLEAGGTQEEAIAALLHDVVEDQGGKPIREDIRQLFGETVLAIIDGCTEWDTPPKPPWQERKLQYLEKLRYALPSVRLVSLADKLHNSRSLLADCQQYGDVIWTNFSAGREKTLWFYQSLVQVYQQTGSDWMTQEIERVVNQLCQENPA
>NZ_CP046704.1|WP_114082195.1|45953_47348_-|TIGR03985-family-CRISPR-associated-protein
MSELVFQDIPDIELLQCLGHGYLKQNLVRAIRLWVWLRSLYGSEGASLYGDNQDRMVLDDSFSYADWRNVFFSSTHPKGEEIPAIHDSHCPCAKTVAEWLFSEKTGVVATHWQKLILAHTGMGESELDTLLQRRLFGVTRRSLQGDLEILAKLGWLVYKYQKYYRVSEFPPRPVTTKDQASAAKVGAYELSFMHEDLVGLAENHSQKINGVQRFFLKLDYVIPRSTLDAVDDLQYELRQLWAKTPVPPIKLTYGSARIANNVDCIVYPVCIYYVQRAVYLCAYGESPQKDTDWYNFRLDHIRSLVALEWTDPKLPLNLQQQYQQKSLPNPDDIALQMAKAWGFDFYLPSQLMLLRFDRQFCDRYVKGTERHDTFEEITYQQVQRLIQREIKQPQQQNLLKVLAKRSETDAYYQAYIRYQDNEHRDNNLVMRLRAWQPKVEVLTPWDLRQSFAADAATQFMLYHN
>NZ_CP046704.1|WP_114082153.1|47450_47756_+|CRISPR-associated-protein-Csx3
MSTYKIELKEGILRINFGEPAQNDQIVRDAAARLEEMATSGELAGGPLLKINGPISIPVAFVLAHKFAHIYGAVAFYDPKLGKYVISITHNPSYKLGDLID
>NZ_CP046704.1|WP_114082154.1|47800_48736_+|CRISPR-associated-protein-Csx3
MTTYHIRLEGDVLKVGFGKDANGDQLVRDAAARLDEMVALGELSGGKLLKIDGPASVAVSYVIAHKISQLYGAIAVFDPKIGRPGYKTFITAVSQTPAYKIGELIETDEPHKPHKTKSVLKVALCGPPQSGKSCLREGLKQAISLIEGAPYPYVITACPDGEGAWFSDAARRDPDLARKLKDEYKAKFTPEFAQKAAGWVRSANTPLNIIDVGGRITDENRVIVREATHAVILASDRGKAEVPLWKEFCRDLNIQIIANLHSDCEGKEDEIVTQSPLLTGSVHYLVRGEDVSSRPMVQALARLLVGLCGKG
>NZ_CP046704.1|WP_114082155.1|48809_50072_+|DUF1887-family-protein
MTTSEFDNNKVDHLFLLIGENPLPNYVTANLLLKKGGTPYLVHTTGTETQAKRLKNILDNKPIGLQPAQLISLGKYESDAYHIQDEIRRKIQSLKNGKIGLNYTGGTKAMAVHAYRAVFSQSHADTVFSYLDARRLEMCIDREDGERIRIKVTPELLEVKLVNLFQLHGLELKQKPTQQAQLPKLAIELANIFKEETKAKQWFDWFYKIFREQAYKNKSNGGGEWKSKISLLEVSTLLDNLPQEIISAFKEENFITPDNKLSLQQVEKTGAFKEIKHFCKWLDGLWLEHYVLEQVKNIADKQIKDYGLNFEIPIKGTRDGFEFDVAFTRGYQLFAISCSTTSKRDLCKSKLFEAYLRARQMGGDEARVALICCFNEPDTLKAEILSSTNDKKIAVFGREHLTNLSEEIANWIDQNDEDAK
>NZ_CP046704.1|WP_114082156.1|50068_51682_+|hypothetical-protein
MRKFTITVIDTSGIQGYIFSSNRLRENIGASHLVSEVTGDWVEETLGVPKNQQKEPIETSGLNVEIIYAGGGNTLIVFKSRKIAINFTRILSKRVLEEAPGINLVVAHKEFDWDEDDLYQVVKDLMEGEIDRRKNERIPSAPLLGLGVTTSCNSTQLPAIDRSNKYIQYGDDEEADSYFTSTETKQKLKAVNRANKKLQEMFADVVDGDIYQFPYRTDHLGRSKRESSYAAIVHADGNGMGKRFQKYGEDAENNRDYIQRMRDFSTSVEEAGKNALKAVVQVVVKSIQEGKVVGKLGEFQLKAKYYLPFRPLVYGGDDITFICEGRLGIELAALFLREFEKQRVADCKKLTACAGICVVKTHYHFAKAYKISEELCKEAKNLVKENKEFEPDGFSAIDWHLAASGLFGSISEIRKLEYQVSVDKKDTWNLAMRPLRLEKHSSEWRTWEGFTQVVKEFKEGENWKERHNKVMALREVLRKADENATKEFLSAYKLSQLPSFPESSGRSEQLARKGWLNNRCGYFDAIEAMEFYLELED
>NZ_CP046704.1|WP_114082157.1|51682_52351_+|RAMP-superfamily-protein
MTIYQLKIKLLSDTTFGRGDGVAGLIDQEVEHDPSGFPYLRGRTLKGLLSEECDNLIAVLPPEIRSEWENFACILFGTPGSVQGTIASMHVGDACLPDDLREAVAFQIKKKTLTTTEVLDSLTTIRRQTAINSETGIADKGSLRSFRVAIRELEFKADLLFETQPSQEILSVLGVGTLALRRIGSGRNRGRGYVRCTLHDDSGVEITQSYISLLGKIQEKSA
>NZ_CP046704.1|WP_114082158.1|52347_53961_+|hypothetical-protein
MKTITFSLHTQQPLLATSFQGDPNSDVSYNYIPGSMIRGAIIGRYMKEYHLSDLDLNDDVVKRLFFDNNTCYLNGYLLSQKKNQEKRTLPVPLSWFKDKDSQLSDNSSQITVYDFSIDEEEKPETPKSVGESFWTEEDGVTFYKEKRRINIHNRRDRKKGRSSQEEGEIFCYDAIDTGQFFQAVILCHEVDADFLKNLLQKSVDIWLGGSQSAGYGYTKISDVNCHDTWNEINIPATERINRECLTITLLSDLIVRDEWGQYAVIPPSKQHQTPAPLTKELEKFLGTLKPQSSFAGNNLVGGFNRKWGLPLPQVPVLKAGSVFVFEKISITSEQIQQLENLGIGERRIEGFGRVAVNWLEKRHFYAKQSESPKISSQPVLKLQTSQTLAAQMAERLLHQKMEHALQKQIGSQEIKGDIKSSQLSRLQMVARQALSTGDCNLALSFLNNLPSNARGQFERAKIKDQSIDKSFKQKLDEWLNNPLSSIKNQQDLIVKIADVERSITDEFAKENKLAEKYTLRLIMAVAKKATKEKRNDS
>NZ_CP046704.1|WP_114082159.1|53950_55372_+|hypothetical-protein
MIHESLRYRNHRRIIERIIIKGRLVLDTPTCLASGDADSDTDLVILRDSLEDKALLMGSSIAGALRNYLRDYKYGYNAEEISVLFGGQRSDEEGEQSPLIINDAISNTVPHIELRDGVKINSITRTAEDGQKYDLELLETGTQFNICFELLIENNREQLIRELVIVLEGLENGKISVGMKKQRGFGRCHVEEWQVWKFDLRKSDERIAWLNFEHWQPGFLPNHPTHESIEEALGLFLDEKEDKRDRLTINATFTLATSLLIRSGQASSDKAPDVVHLKSRRDGELEPVLSGTSLAGVLRHRAERIVNTLQKNTIIIDEIFGVDFSKDKTKKPKASRLIVHESVIKETKDLVQNRIAIDRFTGGALHGALFNEQPIFGSDETELKLELELRQPKPHEIGLLLLLIKDLWTGDLPVGGTSSIGRGRLQGKEATITLASENKIWNITQVSKDESLIIDNAEDLEKFVYALNEEVAT
>NZ_CP046704.1|WP_114082160.1|55368_55932_+|TIGR03984-family-CRISPR-associated-protein
MNKPIRKALDIPTNLDIYQWLEEQAKEYKLRFLLAHAEDGVIWGKFEDGKLLTADSAFDFLPKLRLFTLQQCRAFGERSEVMLWQNNEGFKARLIQDQKDTELIPENQILWGTQADKICGDFTLVSDGSQGLRHAVPLTDIEFDKNQKLYRPLRLSVHHYIDYDDSGVARIDLSRLVNLTTFKEIKK

Crispr_ID: NZ_CP046704_3

• CRISPR_ID: NZ_CP046704_3
• CRISPR_location: 73180-75066
• CRISPR_type: TypeV
• Repeat_type: NA
• Spacer_info: 25 spacers
• Cas_protein_info: cas2,cas1,cas4,cas6,cas5,cas7,cas8a4,cas3

Consensus repeat of NZ_CP046704_3

Consensus_repeat	Method
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	PILER-CR
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	CRISPRCasFinder
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	CRT

spacers of NZ_CP046704_3

>3.1|73217|38|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
ATATTCTGAAATTCGACGGCCATCCGTCGAAGCTATAA
>3.2|73292|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
TAATAGCATTGTTATGAATATAGAGAAAAAGAAAGTG
>3.3|73366|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
ATTAAAGAGTTGGCTAGCGATCGCAGAATATGAACG
>3.4|73439|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
CAATAGTTGGATCTGAAAGCATCTCAACTATTTG
>3.5|73510|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
TTGCCAGTTTCATGGTCTTCTATAAGCACTATGGC
>3.6|73582|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
ATTAAACGTGAAACCTGGATTACTTGGGAGAAATTAG
>3.7|73656|42|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
TAAAGCTGCTCAAGTCCTTGGGTTCTGCCAAATAGCTCTAGG
>3.8|73735|40|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
AATAATTGGGCAACTGCGATCGCAATTACAAAACCACACA
>3.9|73812|38|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
TAATCAGCACACAAAGCACAGTTTAGCTTTATTCCTGC
>3.10|73887|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
AAGAGATTGCCTTTTTCCTCAACCCTGATTAATTCAA
>3.11|73961|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
ATATACTTTTATTTTTGATGCACTCATAAAAGAAG
>3.12|74033|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
CTACATTTTTTAAAGTTAGACTCCAATAGTTAGTAT
>3.13|74106|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
ATTTTTTTCACACCGACTGAAGCAGCAATTTTAAA
>3.14|74178|42|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
CTCCCTAAAGCAATCTTACCTTTGTTAGCTGTCTTTTGCCAG
>3.15|74257|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
TTGTATGAGTAACAACACCTATCAAATTAATCTTGT
>3.16|74330|38|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
ATACTCACGCAGGCTTGATAACTGGTATCAAGGCAATG
>3.17|74405|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
CTCACGATGAGAAAGTGGAGAAGCAAGCCCGTGCTAT
>3.18|74479|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
TTACATTCATGCTTGTAAACTTGTAAAAGAATTAA
>3.19|74551|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
GTTCAGAAATTTTATCCTTAATGTTTTTGTTTGG
>3.20|74622|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
AAGAAGAAACTCATTCCATTAACAAAGTTAGTCCGGC
>3.21|74696|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
TATGAGATGGAAACATCTTGTCCTTTAGCTAATTCCT
>3.22|74770|38|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
CAGAACGATAAGTATAAGGCTGGTGGTCATATAGTACC
>3.23|74845|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
AGAGTTTTTATCAGCATCAAGCAGCATCCCAAATG
>3.24|74917|41|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
ATTCCTTTATGAGTGATTAGCGATCGCTGAGAACTTCAGAG
>3.25|74995|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT
AATTAAAGTTCTCAGCTTTAGCTTGGGCAATAAG

CRISPR arrays and Neighbor proteins around NZ_CP046704_3

CRISPR arrays

The CRISPR arrays of NZ_CP046704_3

>merge|NZ_CP046704|3|73180-75066|PILER-CR,CRISPRCasFinder,CRT
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACATATTCTGAAATTCGACGGCCATCCGTCGAAGCTATAAGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACTAATAGCATTGTTATGAATATAGAGAAAAAGAAAGTGGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACATTAAAGAGTTGGCTAGCGATCGCAGAATATGAACGGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACCAATAGTTGGATCTGAAAGCATCTCAACTATTTGGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACTTGCCAGTTTCATGGTCTTCTATAAGCACTATGGCGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACATTAAACGTGAAACCTGGATTACTTGGGAGAAATTAGGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACTAAAGCTGCTCAAGTCCTTGGGTTCTGCCAAATAGCTCTAGGGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACAATAATTGGGCAACTGCGATCGCAATTACAAAACCACACAGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACTAATCAGCACACAAAGCACAGTTTAGCTTTATTCCTGCGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACAAGAGATTGCCTTTTTCCTCAACCCTGATTAATTCAAGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACATATACTTTTATTTTTGATGCACTCATAAAAGAAGGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACCTACATTTTTTAAAGTTAGACTCCAATAGTTAGTATGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACATTTTTTTCACACCGACTGAAGCAGCAATTTTAAAGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACCTCCCTAAAGCAATCTTACCTTTGTTAGCTGTCTTTTGCCAGGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACTTGTATGAGTAACAACACCTATCAAATTAATCTTGTGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACATACTCACGCAGGCTTGATAACTGGTATCAAGGCAATGGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACCTCACGATGAGAAAGTGGAGAAGCAAGCCCGTGCTATGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACTTACATTCATGCTTGTAAACTTGTAAAAGAATTAAGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACGTTCAGAAATTTTATCCTTAATGTTTTTGTTTGGGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACAAGAAGAAACTCATTCCATTAACAAAGTTAGTCCGGCGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACTATGAGATGGAAACATCTTGTCCTTTAGCTAATTCCTGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACCAGAACGATAAGTATAAGGCTGGTGGTCATATAGTACCGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACAGAGTTTTTATCAGCATCAAGCAGCATCCCAAATGGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACATTCCTTTATGAGTGATTAGCGATCGCTGAGAACTTCAGAGGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACAATTAAAGTTCTCAGCTTTAGCTTGGGCAATAAGGTTTCCAAAGACTATTACCCCAGAAGGGGACTGAAACT

>NZ_CP046704|3|3|73180-75065|PILER-CR
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	ATATTCTGAAATTCGACGGCCATCCGTCGAAGCTATAA
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	TAATAGCATTGTTATGAATATAGAGAAAAAGAAAGTG
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	ATTAAAGAGTTGGCTAGCGATCGCAGAATATGAACG
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	CAATAGTTGGATCTGAAAGCATCTCAACTATTTG
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	TTGCCAGTTTCATGGTCTTCTATAAGCACTATGGC
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	ATTAAACGTGAAACCTGGATTACTTGGGAGAAATTAG
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	TAAAGCTGCTCAAGTCCTTGGGTTCTGCCAAATAGCTCTAGG
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	AATAATTGGGCAACTGCGATCGCAATTACAAAACCACACA
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	TAATCAGCACACAAAGCACAGTTTAGCTTTATTCCTGC
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	AAGAGATTGCCTTTTTCCTCAACCCTGATTAATTCAA
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	ATATACTTTTATTTTTGATGCACTCATAAAAGAAG
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	CTACATTTTTTAAAGTTAGACTCCAATAGTTAGTAT
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	ATTTTTTTCACACCGACTGAAGCAGCAATTTTAAA
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	CTCCCTAAAGCAATCTTACCTTTGTTAGCTGTCTTTTGCCAG
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	TTGTATGAGTAACAACACCTATCAAATTAATCTTGT
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	ATACTCACGCAGGCTTGATAACTGGTATCAAGGCAATG
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	CTCACGATGAGAAAGTGGAGAAGCAAGCCCGTGCTAT
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	TTACATTCATGCTTGTAAACTTGTAAAAGAATTAA
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	GTTCAGAAATTTTATCCTTAATGTTTTTGTTTGG
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	AAGAAGAAACTCATTCCATTAACAAAGTTAGTCCGGC
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	TATGAGATGGAAACATCTTGTCCTTTAGCTAATTCCT
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	CAGAACGATAAGTATAAGGCTGGTGGTCATATAGTACC
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	AGAGTTTTTATCAGCATCAAGCAGCATCCCAAATG
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	ATTCCTTTATGAGTGATTAGCGATCGCTGAGAACTTCAGAG
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	AATTAAAGTTCTCAGCTTTAGCTTGGGCAATAAG
GTTTCCAAAGACTATTACCCCAGAAGGGGACTGAAAC

>NZ_CP046704|3|3|73180-75066|CRISPRCasFinder
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	ATATTCTGAAATTCGACGGCCATCCGTCGAAGCTATAA
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	TAATAGCATTGTTATGAATATAGAGAAAAAGAAAGTG
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	ATTAAAGAGTTGGCTAGCGATCGCAGAATATGAACG
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	CAATAGTTGGATCTGAAAGCATCTCAACTATTTG
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	TTGCCAGTTTCATGGTCTTCTATAAGCACTATGGC
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	ATTAAACGTGAAACCTGGATTACTTGGGAGAAATTAG
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	TAAAGCTGCTCAAGTCCTTGGGTTCTGCCAAATAGCTCTAGG
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	AATAATTGGGCAACTGCGATCGCAATTACAAAACCACACA
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	TAATCAGCACACAAAGCACAGTTTAGCTTTATTCCTGC
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	AAGAGATTGCCTTTTTCCTCAACCCTGATTAATTCAA
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	ATATACTTTTATTTTTGATGCACTCATAAAAGAAG
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	CTACATTTTTTAAAGTTAGACTCCAATAGTTAGTAT
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	ATTTTTTTCACACCGACTGAAGCAGCAATTTTAAA
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	CTCCCTAAAGCAATCTTACCTTTGTTAGCTGTCTTTTGCCAG
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	TTGTATGAGTAACAACACCTATCAAATTAATCTTGT
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	ATACTCACGCAGGCTTGATAACTGGTATCAAGGCAATG
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	CTCACGATGAGAAAGTGGAGAAGCAAGCCCGTGCTAT
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	TTACATTCATGCTTGTAAACTTGTAAAAGAATTAA
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	GTTCAGAAATTTTATCCTTAATGTTTTTGTTTGG
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	AAGAAGAAACTCATTCCATTAACAAAGTTAGTCCGGC
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	TATGAGATGGAAACATCTTGTCCTTTAGCTAATTCCT
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	CAGAACGATAAGTATAAGGCTGGTGGTCATATAGTACC
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	AGAGTTTTTATCAGCATCAAGCAGCATCCCAAATG
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	ATTCCTTTATGAGTGATTAGCGATCGCTGAGAACTTCAGAG
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	AATTAAAGTTCTCAGCTTTAGCTTGGGCAATAAG
GTTTCCAAAGACTATTACCCCAGAAGGGGACTGAAACT

>NZ_CP046704|3|3|73180-75065|CRT
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	ATATTCTGAAATTCGACGGCCATCCGTCGAAGCTATAA
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	TAATAGCATTGTTATGAATATAGAGAAAAAGAAAGTG
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	ATTAAAGAGTTGGCTAGCGATCGCAGAATATGAACG
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	CAATAGTTGGATCTGAAAGCATCTCAACTATTTG
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	TTGCCAGTTTCATGGTCTTCTATAAGCACTATGGC
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	ATTAAACGTGAAACCTGGATTACTTGGGAGAAATTAG
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	TAAAGCTGCTCAAGTCCTTGGGTTCTGCCAAATAGCTCTAGG
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	AATAATTGGGCAACTGCGATCGCAATTACAAAACCACACA
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	TAATCAGCACACAAAGCACAGTTTAGCTTTATTCCTGC
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	AAGAGATTGCCTTTTTCCTCAACCCTGATTAATTCAA
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	ATATACTTTTATTTTTGATGCACTCATAAAAGAAG
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	CTACATTTTTTAAAGTTAGACTCCAATAGTTAGTAT
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	ATTTTTTTCACACCGACTGAAGCAGCAATTTTAAA
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	CTCCCTAAAGCAATCTTACCTTTGTTAGCTGTCTTTTGCCAG
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	TTGTATGAGTAACAACACCTATCAAATTAATCTTGT
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	ATACTCACGCAGGCTTGATAACTGGTATCAAGGCAATG
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	CTCACGATGAGAAAGTGGAGAAGCAAGCCCGTGCTAT
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	TTACATTCATGCTTGTAAACTTGTAAAAGAATTAA
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	GTTCAGAAATTTTATCCTTAATGTTTTTGTTTGG
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	AAGAAGAAACTCATTCCATTAACAAAGTTAGTCCGGC
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	TATGAGATGGAAACATCTTGTCCTTTAGCTAATTCCT
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	CAGAACGATAAGTATAAGGCTGGTGGTCATATAGTACC
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	AGAGTTTTTATCAGCATCAAGCAGCATCCCAAATG
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	ATTCCTTTATGAGTGATTAGCGATCGCTGAGAACTTCAGAG
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	AATTAAAGTTCTCAGCTTTAGCTTGGGCAATAAG
GTTTCCAAAGACTATTACCCCAGAAGGGGACTGAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046704.1|WP_114082168.1|68236_69199_+|DevR-family-CRISPR-associated-autoregulator	cas7	pfam01905_cas7_CAS-I	gnl|CDD|376656
NZ_CP046704.1|WP_114082169.1|69179_69950_+|hypothetical-protein	cas5	cls000048_cas5_CAS-I-A	unknown
NZ_CP046704.1|WP_114082176.1|81884_82586_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|271000
NZ_CP046704.1|WP_114082179.1|83926_84388_-|cupin-domain-containing-protein	unknown	unknown	gnl|CDD|226357
NZ_CP046704.1|WP_114082173.1|72666_72960_+|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187856
NZ_CP046704.1|WP_114082175.1|78936_79926_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|224343
NZ_CP046704.1|WP_114082177.1|82702_82918_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046704.1|WP_114082171.1|70980_71580_+|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl|CDD|273040
NZ_CP046704.1|WP_114082167.1|66408_68244_+|hypothetical-protein	cas8a4	cls000706_cas8a4_CAS-I-A	unknown
NZ_CP046704.1|WP_159402624.1|80205_80346_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046704.1|WP_114082174.1|75214_76366_+|CRISPR-associated-endoribonuclease-Cas6	cas6	COG5551_cas6_CAS-III	gnl|CDD|227838
NZ_CP046704.1|WP_114082165.1|63406_64033_+|DEAD/DEAH-box-helicase-family-protein	cas3	COG1203_cas3_CAS-I	gnl|CDD|214692
NZ_CP046704.1|WP_114082198.1|86191_88087_+|DUF3370-family-protein	unknown	unknown	gnl|CDD|314680
NZ_CP046704.1|WP_114082170.1|69927_70953_+|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	pfam10040_cas6_CAS-III:CAS-IV	gnl|CDD|337605
NZ_CP046704.1|WP_114082197.1|84987_86073_+|WD40-repeat-domain-containing-protein	unknown	unknown	gnl|CDD|238121
NZ_CP046704.1|WP_114082180.1|88365_88605_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046704.1|WP_114082172.1|71659_72637_+|type-I-D-CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|274976
NZ_CP046704.1|WP_159402625.1|83160_83565_+|ATP-dependent-DNA-helicase	unknown	unknown	unknown
NZ_CP046704.1|WP_114082166.1|64013_66059_+|CRISPR-associated-helicase-Cas3'	cas3	COG1203_cas3_CAS-I	gnl|CDD|224124
NZ_CP046704.1|WP_114082164.1|63065_63281_-|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|226983

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP046704.1|WP_114082174.1|75214_76366_+|CRISPR-associated-endoribonuclease-Cas6	cas6	COG5551_cas6_CAS-III	2.8e-73	241.4	0.2
NZ_CP046704.1|WP_114082168.1|68236_69199_+|DevR-family-CRISPR-associated-autoregulator	cas7	pfam01905_cas7_CAS-I	2.8e-46	152.4	0.0
NZ_CP046704.1|WP_114082169.1|69179_69950_+|hypothetical-protein	cas5	cls000048_cas5_CAS-I-A	1.1e-88	291.5	0.0
NZ_CP046704.1|WP_114082170.1|69927_70953_+|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	pfam10040_cas6_CAS-III:CAS-IV	6.7e-23	76.3	0.0
NZ_CP046704.1|WP_114082165.1|63406_64033_+|DEAD/DEAH-box-helicase-family-protein	cas3	COG1203_cas3_CAS-I	7.7e-26	85.2	0.6
NZ_CP046704.1|WP_114082172.1|71659_72637_+|type-I-D-CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	6.2e-103	338.8	0.0
NZ_CP046704.1|WP_114082173.1|72666_72960_+|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	1.6e-25	83.8	0.0
NZ_CP046704.1|WP_114082166.1|64013_66059_+|CRISPR-associated-helicase-Cas3'	cas3	COG1203_cas3_CAS-I	7.4e-41	134.9	0.1
NZ_CP046704.1|WP_114082171.1|70980_71580_+|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	9e-35	115.1	0.3
NZ_CP046704.1|WP_114082167.1|66408_68244_+|hypothetical-protein	cas8a4	cls000706_cas8a4_CAS-I-A	5.8e-34	112.0	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046704.1|WP_114082168.1|68236_69199_+|DevR-family-CRISPR-associated-autoregulator	gnl|CDD|376656	pfam01905, DevR, CRISPR-associated negative auto-regulator DevR/Csa2. This group of families is one of several protein families that are always found associated with prokaryotic CRISPRs, themselves a family of clustered regularly interspaced short palindromic repeats, DNA repeats found in nearly half of all bacterial and archaeal genomes. These DNA repeat regions have a remarkably regular structure: unique sequences of constant size, called spacers, sit between each pair of repeats. It has been shown that the CRISPRs are virus-derived sequences acquired by the host to enable them to resist viral infection. The Cas proteins from the host use the CRISPRs to mediate an antiviral response. After transcription of the CRISPR, a complex of Cas proteins termed Cascade cleaves a CRISPR RNA precursor in each repeat and retains the cleavage products containing the virus-derived sequence. Assisted by the helicase Cas3, these mature CRISPR RNAs then serve as small guide RNAs that enable Cascade to interfere with virus proliferation. Cas5 contains an endonuclease motif, whose inactivation leads to loss of resistance, even in the presence of phage-derived spacers. This family used to be known as DUF73. DevR appears to be negative auto-regulator within the system.	1.45787e-60
NZ_CP046704.1|WP_114082176.1|81884_82586_+|serine/threonine-protein-kinase	gnl|CDD|271000	cd14098, STKc_Rad53_Cds1, Catalytic domain of the yeast Serine/Threonine Kinases, Rad53 and Cds1. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. Rad53 and Cds1 are the checkpoint kinase 2 (Chk2) homologs found in budding and fission yeast, respectively. They play a central role in the cell's response to DNA lesions to prevent genome rearrangements and maintain genome integrity. They are phosphorylated in response to DNA damage and incomplete replication, and are essential for checkpoint control. They help promote DNA repair by stalling the cell cycle prior to mitosis in the presence of DNA damage. The Rad53/Cds1 subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	0.00289965
NZ_CP046704.1|WP_114082179.1|83926_84388_-|cupin-domain-containing-protein	gnl|CDD|226357	COG3837, COG3837, Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown].	8.04873e-62
NZ_CP046704.1|WP_114082173.1|72666_72960_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.62838e-26
NZ_CP046704.1|WP_114082175.1|78936_79926_+|helix-turn-helix-domain-containing-protein	gnl|CDD|224343	COG1426, COG1426, Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown].	4.36209e-20
NZ_CP046704.1|WP_114082171.1|70980_71580_+|CRISPR-associated-protein-Cas4	gnl|CDD|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	1.21624e-34
NZ_CP046704.1|WP_114082174.1|75214_76366_+|CRISPR-associated-endoribonuclease-Cas6	gnl|CDD|227838	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	1.78779e-58
NZ_CP046704.1|WP_114082165.1|63406_64033_+|DEAD/DEAH-box-helicase-family-protein	gnl|CDD|214692	smart00487, DEXDc, DEAD-like helicases superfamily.	1.33515e-23
NZ_CP046704.1|WP_114082198.1|86191_88087_+|DUF3370-family-protein	gnl|CDD|314680	pfam11850, DUF3370, Protein of unknown function (DUF3370). This family of proteins are functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 452 to 532 amino acids in length.	0
NZ_CP046704.1|WP_114082170.1|69927_70953_+|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	gnl|CDD|337605	pfam10040, CRISPR_Cas6, CRISPR-associated endoribonuclease Cas6. Cas6 is a member of the RAMP (repeat-associated mysterious protein) superfamily. It is among the most widely distributed Cas proteins and is found in both bacteria and archaea. Cas6 functions in the generation of CRISPR-derived guide RNAs for invader defense in prokaryotes.	2.06948e-13
NZ_CP046704.1|WP_114082197.1|84987_86073_+|WD40-repeat-domain-containing-protein	gnl|CDD|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	1.07467e-54
NZ_CP046704.1|WP_114082172.1|71659_72637_+|type-I-D-CRISPR-associated-endonuclease-Cas1	gnl|CDD|274976	TIGR04093, hypothetical_protein_L8106_25395, CRISPR-associated endonuclease Cas1, subtype CYANO. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes a clade of Cas1 limited to the CYANO subtype of CRISPR/Cas system and most often the type found there.	5.17419e-148
NZ_CP046704.1|WP_114082166.1|64013_66059_+|CRISPR-associated-helicase-Cas3'	gnl|CDD|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	6.33476e-29
NZ_CP046704.1|WP_114082164.1|63065_63281_-|Uma2-family-endonuclease	gnl|CDD|226983	COG4636, Uma2, Endonuclease, Uma2 family (restriction endonuclease fold) [General function prediction only].	0.00101941

Protein sequences

>NZ_CP046704.1|WP_114082173.1|72666_72960_+|CRISPR-associated-endonuclease-Cas2
MTTLFYLIIYDLPDNKAANKRRTRLHKMLSGYGKWTQYSVFECFLTAIQFATLQTKIEKLVKPEEDSVRLYILDAGAIKRTITYGSEIPRQEQTIVL
>NZ_CP046704.1|WP_114082172.1|71659_72637_+|type-I-D-CRISPR-associated-endonuclease-Cas1
MSVLYVTQADAVLSKNYEAFNVALKQSDGSWKKQTVAAQTVEQVVLMGNPQVTGDALVYALELGMPVHYLSSFGKYLGSALPGYSRNGQLRLAQYKLYSDPVGRLELVKAIVTAKIHNQYQVLYRHNERDNPLKERKSLVKSQKTIDQVRGIEGLAAREYFACWPRMVGKQWTFTGRNRRPPTDPVNSLLSFAYGLLRVQVTAAVHVAGLDPYIGYLHEVHHGQPAMVLDLMEEFRSLIADNVVLAVLHKHEIQPDDFNESLGAYRLKDSARKTFLQAFERKMNDEFKHPVFEYRCTYRRAIELQARLLGRHLQEGIPYKAFALR
>NZ_CP046704.1|WP_114082171.1|70980_71580_+|CRISPR-associated-protein-Cas4
MNEDYLPLAYLNAWEYCPRRFYLEYVLGEMSDNEHIILGRHIHRNINEEGTLQEGEMLIHQQQWVWSDRLKVAGIIDAVEECDGQLVPVEYKKGKMAQHLNDHFQLCAAALCLEERTGRCLAYGEIFYHTNRRRQTVAFTPQLRQMTEQAIVLAQLASQTTMPVPIDNTKKCLSCSLKEICLPFEVKQLRVSMTSETED
>NZ_CP046704.1|WP_114082170.1|69927_70953_+|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6
MICTKDTEVTFAGLSIVLKQVETSISPTPLNSWLSETQLLPVWIPLRINGGVTKIMPVLPSSVLYSNLMQSICQQIAQNTLVEWWQKPYELTGVEVDSDALHVIQVSVTSAASLPALGRAIHAQCFQWFANADTALAEHLHQQNTLPLTAAMQYVSPQKMQLRITLLKKELLAPLLWGLSTNLGESIMLAGIPCQLGKWIDIVQVSSFEKLLQVTTQSVIELRFLSPTSFKQNRGVQSFPLPELVFNSLLRRWNIFAPPEQQFPEVEWNGLVSAYDLKTHALKMEGGAEIGAQGWVKYRFLDSQQARIATILAHFATFAGVGRKTAMGMGQVRLVESRLRG
>NZ_CP046704.1|WP_114082169.1|69179_69950_+|hypothetical-protein
MPKPSNKSKSSLSKQEQQVKVNSNQWLTLTYQPVSLFSLKRSDATSMAARSNLVPTPYAIKMALLKVLLESQGRQHQSNFDQWIKSEFTWIRDLQIYIWPPEQLVVNRNGYKLRYYDQTADKADKSRTTLPMQGGFVFREWVHLQGHLQICCGGCDRLAELERLFAQINYFGKRGCFFQYLPEYKQETSEPLFQPNLITGFTAQLMDDLGEKATFNRINPFSTEKAQLDKDRVIKPGFLPLRLVATSARYDMYQRY
>NZ_CP046704.1|WP_114082168.1|68236_69199_+|DevR-family-CRISPR-associated-autoregulator
MTNTHFPVHSISVSGTLSWQLHALNNEGNEGNQSLTRRYYIIQKDMTEPEYVNGVSGDMLKHIQAEHLHRIAIQEGLTLSEGGKQFHPDRIGYDLEKGLPVFTQSNTDLTAKTNQVLQLCTISDLEGFMVTVKGGQTLKRESVIEFGAAVGLPTLVKTQSYFHAKYGTDNPTPYNVQVNSGLYATVLNIEAFRIGYNPHNFSYSIDPIERKKRLDVLLKSVLYTYLQPNGAKRNTHLPHPDHFEGVITVSTRRCPAPMLSPLSASYSRQIHSLADTLNNLNGAGTIHCFDFETIAQFAEQIQTLIERSQPWESNNAEAIE
>NZ_CP046704.1|WP_114082167.1|66408_68244_+|hypothetical-protein
MTERLFITKKFGTYADTFLMLGLVQLVEYALKATNQKIDIQLVDEGTRYCIQLKKAVNLEPIGKLSYTNPFPPVKGKKTDISKISQETIIFDTVEQSDARKLYRDYVFQQRGKVQFHEDAPDPPHPSTQNGVVLTSMRHDRNHNELWQLGWQNKDDYGILLVTLFQAFSQENYSSLNGETKQVAELFKQATGRQLPSEASAVKVYLPTSVQGVNRIKADSNKVDSQKADWLTLWLIAGGLFSFGVAERVKIAERVYDWRVVALEPLDIQLSKYREVLDKLRKYNPPSGGYGIARFDAELVLRFCQQLLNSHPSQADAELDDFDLWQPINHFVSNFVGTHFGSKGQVYGVKEVFTLGLPGWIRPENSEELTDYLKVLNEHLFVIGSLSAEEGHSELLAAYRDFITGTNLRRFFRFQASYADYIVKRLADPKAKPPRLFSIAGLNTMTKKDTDFTKITTDPSFLRIAKAINQATVYAGKVKTQQGVIELDWQRTYGLAQRLSSQSGSKKDFLSEITDFLAKYQAENLRLSEQLLKEGKSLRRVWTTKEDLDRLVELVENYDTVLVANLLIAYGYARWTKAKEVDLEDENADINDEQDLNNLEPTENLGESNND
>NZ_CP046704.1|WP_114082166.1|64013_66059_+|CRISPR-associated-helicase-Cas3'
MEIIQVEDADLQAIEGDRCRTFQAVSHPLNASVILDDIRAYQRKRVIIICNTVSQAQGLFRDLEELNYEGILHVTLLHSRFLPEHRAQKETDLKSIFAQSWQDDGNCYVLISTQVIEAGINITCQVMHTQLCPMNSLLQRAGRCARFGGEQGEVYIYPTVEVNAASCKIAIADLELEEESAPKKQSFLPYPQETCELTWSVLQEHTQSVQANENVGFRTEEQWINQVHTREDLLQQQRRLNNRMNFEQRFEDAFFRGDQSAGRELIRSIDSRSVFIWEEDGLIDIEEEVVDPQKLLSFSLPVSMLCKVWREFQNMEFGADWIFKQIENPKGKAETYSQPVCTPIKSREALIGSIRILVNPRYVHYDEHIGLLIGIDVFGNHFVSPDKSKRVIASEYRYNMDNYVGHLVLMWKCWREVFTVNRLKNGVSQETTFTSVRDELLAAGGRFIRGKIFPQTQEKEAEALFEMLVFLAIFTHDLGKLQVKWQEVMQGWQAIAHSSFSGRNPGKHLLAHTDYSPEDRHQRDALKDYEKKHKRPNHAVESAYLAQDILKQSLVPLLQDNFLADIEQIKYICHTVIMAAGRHHSAWAGGWDQAATAKIKSIELHPGAKQAIADSWRSIHRFLPQPLSLAKANLGKDVYPIKKDFDLNRFTPDQTEYLQLYLLIVRALRLCDQRSVQLHNI
>NZ_CP046704.1|WP_114082165.1|63406_64033_+|DEAD/DEAH-box-helicase-family-protein
MISEYFQTLTTFPPRNFQREAIAKLLQRQDILLRAPTGSGKTETAIAPFLFAKALNIDFPNKLIYVVPLRTLANSLRQRAEILIANWEKVYPSSHFLAVTLQTGENPEDPRFEGDIVFCTIDQMLSSFLNIPYSVGRGSANVNSGAIFASYLVFDELHLLDPDRSFATVLKVLQQVKGISPFLLMTATLTNELATQIQTLVNNGNYSS
>NZ_CP046704.1|WP_114082164.1|63065_63281_-|Uma2-family-endonuclease
MLLTEHRADRVVLYNISWQKFENLLVDLGESRSARVAYDDGTLEIMTPLPEHEYYKEIIGDILNLTPLKVA
>NZ_CP046704.1|WP_114082174.1|75214_76366_+|CRISPR-associated-endoribonuclease-Cas6
MPRAASSTSGKPKPKQKSVASVVTWADETELVGLVFELESTASALLYSQYTIGLHAWFLEQVRQFDPDLSAYLHDGESEKPFNISALSGQLIASGKQLRLEGNQIYYWYVNVLSQRVAKFLKHWLTQLPERLDLKGASLQIKQVSIAYAPTTYKQLLESSTDRPSSISLSFISPTSFRRKGNHFPLPVPENLFHSYLRRWNDFSSMPAEQESFLKWIDEGVIIHQHRLKSEKVAAGKRGSVTGFTGAISLGLTKAASANFEFSELFYALVRLAPYCGTGHKTTFGLGQTRLDWVEQETSKSIQLITNLLGERIEELIKLFTAQRKRTGGERTDKIAVTWATILARREMGESLKAIAEDLEMPISTVKTYVKLARKSLKQESNS
>NZ_CP046704.1|WP_114082175.1|78936_79926_+|helix-turn-helix-domain-containing-protein
MVTTPVYYLQFLDNPNIEISQDELRSLLGEIEVQLHRSRVYRRALAIVQKLIGEQTDQAQDLLKAVGREAIGLAFQRFAQQSQKVETVTDNKQATETVNSSPEIQQEHCALREEPSKNTAENSLWKKTLQLLNHQRISQAELAEQAELAAQQRMVCLRQIGQQLQKTRQSKGLSLDHIQLSTHIRTELIEALENGNWKELSDDIFVRGFIRRYGDALGLNGVALAASLPFLAAIPVTQPFSDQSKKGGGLEIRPTHLYIGYTALLAGAMGGLTLMSQQQANTNISIEQDNSSSAFQSLKQQSPTVKPGIKYTNTGVAVGSDIFPPEGLY
>NZ_CP046704.1|WP_159402624.1|80205_80346_-|hypothetical-protein
MLLFVGGGENATPNSPPQASLSQAGLWAGCDRSLSVSPSPIEENQR
>NZ_CP046704.1|WP_114082176.1|81884_82586_+|serine/threonine-protein-kinase
MDKLLPEQLVKSIYQELLPRLQIESVNPRNPIQVSYLPQPWQLLGKGNYAAVVFHPDYPECVVKIYAPGRLGFEEEVEVYRRLGSHPAFSECLYAKDNFLILKRLYGTTLYDCMHLGLPIPQQVIRDIDKALDYARSRGLHPHDVHGRNVMMHQGRGLVVDISDFLHPEACSKWNHLKKAYYWLYRPVLRPLGLRVPYSALNMLRKSYRLATSFKISCCQLVLRLTRFKYLKL
>NZ_CP046704.1|WP_114082177.1|82702_82918_-|hypothetical-protein
MNNQPNHENLSPQETPCPICGSQNFVWGRTVGESVSQWVYFRADGAGWGEGEKLRARKCRDCNNVQLFSYD
>NZ_CP046704.1|WP_159402625.1|83160_83565_+|ATP-dependent-DNA-helicase
MQNILAIYKLSKTRIKGYMNRLKSLLLGGLLASVSIAALSTHANASVVNFRNEHLNTNTIAFNNAKLIRERQLHEQQAREQKARELRERQVREQKARELRERQAREQKARELRERQAREQKARELRERQARFHH
>NZ_CP046704.1|WP_114082179.1|83926_84388_-|cupin-domain-containing-protein
MTVITPDRLVVEESPSHAAHEPNRTLWISEAGGLTLFGAFIEVLQPGSRSSIKHWHRAEDEMVYVLEGEITLIEGDTKTVLRPGDAATFQAGVAVGHFLENRSALATRCLVVGNRAAVDTITYPDLDRVCHRDRSLPDDIWTNSLGEPAPSPY
>NZ_CP046704.1|WP_114082197.1|84987_86073_+|WD40-repeat-domain-containing-protein
MTMKLPILFKTLTLLSFFLPIPFSMIANVPVIANTLNTPTNTEQPKRLKRTLSGHTAPVRALTLSPSGQVLASGSDDKTIKLWNATTGALLYTLTGHREGIKSIVFTPDEQTLISTSFDNTIKFWNTQTGKEVCTISEKTGVKAMLLTLDGQTLISGSGDNTIKFRNLKTRKIDRILKAETTALAITPDGKTLLSGGENGGRIRVWSLVTGKQIGSFTPPLPKKEDLISGSERASAPITLAVSKDGKMLLCGGYDDSFQSGGVRSTDGKGFKAWDLKTGKLVHDLSFGTSIDALIISPDSKTFIAGGLGREIILRDIKTGKSVMELTGHAGGIYGLAISSDGKILYSGSGDKSVKVWQIKV
>NZ_CP046704.1|WP_114082198.1|86191_88087_+|DUF3370-family-protein
MLLKKTLLVVFLLTLSTPNALAFSDTESYWAKHCIQQLKERKLITGYPDGSFRPETTVTRAQAAVLMLNAFPDSPVKRTAASFKDVPADYWANKAISTAYQKGFFSGYPGGIFQPNQPIPRAQIIGVVAAGKNYSPLPSPMQTLQQYFNDVGQIPNYAQNAIASATINSIVVNYPNVKQLKPLQSATRGEVAALMCRALNIYTVPPQYIAGVEVDSQEIRPLPGKLDLIPTFNSNSPELVTTEGILLSTFPPDGKQVHEAHLNYPFEGRFDIFAHHIVRAETPAQSLTVYQGIIVHNPGNEPVTVQVLQAASYLTKEAQFIALADMVENPQGTVYSGPGDRTMNDVLRGVRQEIFPEKLVIEPKETKILANLPIQVQAPSSNGRTTMMRLTSSSPVYIANLVKNSNISPTLGEWQELLDTGSLAGKRDPIPTPLDPPREPTVFSRVAGVSQGTQWKTQITDNSNVSELTIPSPGKAFSYPLGTVHLITLSTGQIQSAAMLKRYPDTAYFAHSNYGVEYNLTLPLRNITSETQTITVSIQTPVKDEGGTDRLLFLKPGVEQIFFRGTVRVRYIDDNGVEKTRYVHLVQRRGQRGEPLVTLKMLASEKRQVQIDFLYPPDSTPPQVLTVRTKR
>NZ_CP046704.1|WP_114082180.1|88365_88605_+|hypothetical-protein
MITQMMVQPSFWVESGIKLSKVRDIHLFKFTEELQSRLEELSEKKKAGLLTTEEDAELAGILELDRIFTLLNAKIISES

Crispr_ID: NZ_CP046704_4

• CRISPR_ID: NZ_CP046704_4
• CRISPR_location: 76706-78355
• CRISPR_type: TypeV
• Repeat_type: NA
• Spacer_info: 22 spacers
• Cas_protein_info: cas6,cas2,cas1,cas4,cas5,cas7,cas8a4,cas3

Consensus repeat of NZ_CP046704_4

Consensus_repeat	Method
GTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAAC	CRISPRCasFinder
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	CRT

spacers of NZ_CP046704_4

>4.1|76743|38|NZ_CP046704|CRISPRCasFinder,CRT
GTTCAAATGCTGTCTCTTATCAAAATCAAGTTCGAGGA
>4.2|76818|35|NZ_CP046704|CRISPRCasFinder,CRT
TAATAGCATTGTTATGAATATAGAGAAAAAGAAAG
>4.3|76890|37|NZ_CP046704|CRISPRCasFinder,CRT
ATATCTGAATTTTTCGAGACTGGGAATATTCATAACT
>4.4|76964|34|NZ_CP046704|CRISPRCasFinder,CRT
AATTAACTGGTTGCGCCTGCTCAACAACAATCGA
>4.5|77035|36|NZ_CP046704|CRISPRCasFinder,CRT
ACCACCGGAGGCAGAAGGAAATCTGGTGATCGTATC
>4.6|77108|36|NZ_CP046704|CRISPRCasFinder,CRT
TAACTGCTCTGCCACTTCCCGATAGTCATCTGCGAT
>4.7|77181|37|NZ_CP046704|CRISPRCasFinder,CRT
CCCAAGAGAATATTGACGCTTTAGTTCATCTAGAAAG
>4.8|77255|37|NZ_CP046704|CRISPRCasFinder,CRT
ATCACACGCTTGGTGATAACGCAATACTAGGACTACA
>4.9|77329|37|NZ_CP046704|CRISPRCasFinder,CRT
TCATCTTGAAAGCCACTTACCAAAGAATTGGATTAAG
>4.10|77403|35|NZ_CP046704|CRISPRCasFinder,CRT
CTGTACTTCTCTAAAAAGATGGAAATTCCAGGTGG
>4.11|77475|35|NZ_CP046704|CRISPRCasFinder,CRT
GCTAGAGGCGATCGCTATCTATACTCGCCTCCAAC
>4.12|77547|37|NZ_CP046704|CRISPRCasFinder,CRT
GGGTTATTAAGCTTTACACTACCCTTTCTAAAGCCAT
>4.13|77621|38|NZ_CP046704|CRISPRCasFinder,CRT
ATTTTTATCGCTCAGATGCACCATACAAAAACTTACTG
>4.14|77696|36|NZ_CP046704|CRISPRCasFinder,CRT
TTCAATCCACGCTTTCATTATTCCAACAATTTATGC
>4.15|77769|35|NZ_CP046704|CRISPRCasFinder,CRT
CTACTTCGGTTGTCATAGTGTGTTAGTCGTTTTTG
>4.16|77841|37|NZ_CP046704|CRISPRCasFinder,CRT
GTTCCGTTACCCATGTCAATTAATGTCCAATCCCTAT
>4.17|77915|36|NZ_CP046704|CRISPRCasFinder,CRT
TTCGTAAGCATACCCTCTGCAATCAGACAAAGGATG
>4.18|77988|36|NZ_CP046704|CRISPRCasFinder,CRT
CAAATCAATGGTTGTCTGTGCCTGTTAATAACATTA
>4.19|78061|37|NZ_CP046704|CRISPRCasFinder,CRT
TCAAATTCAATTACTTGATGAAACTCACCCAAGACAG
>4.20|78135|35|NZ_CP046704|CRISPRCasFinder,CRT
GCAGCAGTAGCTCGCTTGGATCATCCGGCAGTTTG
>4.21|78207|38|NZ_CP046704|CRISPRCasFinder,CRT
ATCATTTAGTTTGATTCTAAACTTTCCAATTGGGCTGC
>4.22|78282|37|NZ_CP046704|CRISPRCasFinder,CRT
GAAAAAGCGGCAATGCGATCGTTTTCGTTAGAAAAAT

CRISPR arrays and Neighbor proteins around NZ_CP046704_4

CRISPR arrays

The CRISPR arrays of NZ_CP046704_4

>merge|NZ_CP046704|4|76706-78355|CRISPRCasFinder,CRT
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACGTTCAAATGCTGTCTCTTATCAAAATCAAGTTCGAGGAGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACTAATAGCATTGTTATGAATATAGAGAAAAAGAAAGGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACATATCTGAATTTTTCGAGACTGGGAATATTCATAACTGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACAATTAACTGGTTGCGCCTGCTCAACAACAATCGAGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACACCACCGGAGGCAGAAGGAAATCTGGTGATCGTATCGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACTAACTGCTCTGCCACTTCCCGATAGTCATCTGCGATGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACCCCAAGAGAATATTGACGCTTTAGTTCATCTAGAAAGGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACATCACACGCTTGGTGATAACGCAATACTAGGACTACAGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACTCATCTTGAAAGCCACTTACCAAAGAATTGGATTAAGGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACCTGTACTTCTCTAAAAAGATGGAAATTCCAGGTGGGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACGCTAGAGGCGATCGCTATCTATACTCGCCTCCAACGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACGGGTTATTAAGCTTTACACTACCCTTTCTAAAGCCATGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACATTTTTATCGCTCAGATGCACCATACAAAAACTTACTGTTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACTTCAATCCACGCTTTCATTATTCCAACAATTTATGCGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACCTACTTCGGTTGTCATAGTGTGTTAGTCGTTTTTGGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACGTTCCGTTACCCATGTCAATTAATGTCCAATCCCTATGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACTTCGTAAGCATACCCTCTGCAATCAGACAAAGGATGGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACCAAATCAATGGTTGTCTGTGCCTGTTAATAACATTAGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACTCAAATTCAATTACTTGATGAAACTCACCCAAGACAGGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACGCAGCAGTAGCTCGCTTGGATCATCCGGCAGTTTGGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACATCATTTAGTTTGATTCTAAACTTTCCAATTGGGCTGCGTTTCCATTGACCAAATCCCCTCACGGGGACTGAAACGAAAAAGCGGCAATGCGATCGTTTTCGTTAGAAAAATGTTTCCATTGACCAAATCCCCTCACGAGGACTGAAAC

>NZ_CP046704|4|4|76706-78355|CRISPRCasFinder
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	GTTCAAATGCTGTCTCTTATCAAAATCAAGTTCGAGGA
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	TAATAGCATTGTTATGAATATAGAGAAAAAGAAAG
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	ATATCTGAATTTTTCGAGACTGGGAATATTCATAACT
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	AATTAACTGGTTGCGCCTGCTCAACAACAATCGA
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	ACCACCGGAGGCAGAAGGAAATCTGGTGATCGTATC
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	TAACTGCTCTGCCACTTCCCGATAGTCATCTGCGAT
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	CCCAAGAGAATATTGACGCTTTAGTTCATCTAGAAAG
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	ATCACACGCTTGGTGATAACGCAATACTAGGACTACA
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	TCATCTTGAAAGCCACTTACCAAAGAATTGGATTAAG
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	CTGTACTTCTCTAAAAAGATGGAAATTCCAGGTGG
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	GCTAGAGGCGATCGCTATCTATACTCGCCTCCAAC
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	GGGTTATTAAGCTTTACACTACCCTTTCTAAAGCCAT
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	ATTTTTATCGCTCAGATGCACCATACAAAAACTTACTG
TTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	TTCAATCCACGCTTTCATTATTCCAACAATTTATGC
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	CTACTTCGGTTGTCATAGTGTGTTAGTCGTTTTTG
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	GTTCCGTTACCCATGTCAATTAATGTCCAATCCCTAT
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	TTCGTAAGCATACCCTCTGCAATCAGACAAAGGATG
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	CAAATCAATGGTTGTCTGTGCCTGTTAATAACATTA
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	TCAAATTCAATTACTTGATGAAACTCACCCAAGACAG
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	GCAGCAGTAGCTCGCTTGGATCATCCGGCAGTTTG
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	ATCATTTAGTTTGATTCTAAACTTTCCAATTGGGCTGC
GTTTCCATTGACCAAATCCCCTCACGGGGACTGAAAC	GAAAAAGCGGCAATGCGATCGTTTTCGTTAGAAAAAT
GTTTCCATTGACCAAATCCCCTCACGAGGACTGAAAC

>NZ_CP046704|4|4|76706-78355|CRT
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	GTTCAAATGCTGTCTCTTATCAAAATCAAGTTCGAGGA
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	TAATAGCATTGTTATGAATATAGAGAAAAAGAAAG
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	ATATCTGAATTTTTCGAGACTGGGAATATTCATAACT
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	AATTAACTGGTTGCGCCTGCTCAACAACAATCGA
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	ACCACCGGAGGCAGAAGGAAATCTGGTGATCGTATC
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	TAACTGCTCTGCCACTTCCCGATAGTCATCTGCGAT
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	CCCAAGAGAATATTGACGCTTTAGTTCATCTAGAAAG
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	ATCACACGCTTGGTGATAACGCAATACTAGGACTACA
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	TCATCTTGAAAGCCACTTACCAAAGAATTGGATTAAG
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	CTGTACTTCTCTAAAAAGATGGAAATTCCAGGTGG
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	GCTAGAGGCGATCGCTATCTATACTCGCCTCCAAC
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	GGGTTATTAAGCTTTACACTACCCTTTCTAAAGCCAT
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	ATTTTTATCGCTCAGATGCACCATACAAAAACTTACTG
TTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	TTCAATCCACGCTTTCATTATTCCAACAATTTATGC
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	CTACTTCGGTTGTCATAGTGTGTTAGTCGTTTTTG
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	GTTCCGTTACCCATGTCAATTAATGTCCAATCCCTAT
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	TTCGTAAGCATACCCTCTGCAATCAGACAAAGGATG
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	CAAATCAATGGTTGTCTGTGCCTGTTAATAACATTA
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	TCAAATTCAATTACTTGATGAAACTCACCCAAGACAG
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	GCAGCAGTAGCTCGCTTGGATCATCCGGCAGTTTG
GTTTCCACCAACCAAATCCCCTCACGGGGACTGAAAC	ATCATTTAGTTTGATTCTAAACTTTCCAATTGGGCTGC
GTTTCCATTGACCAAATCCCCTCACGGGGACTGAAAC	GAAAAAGCGGCAATGCGATCGTTTTCGTTAGAAAAAT
GTTTCCATTGACCAAATCCCCTCACGAGGACTGAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046704.1|WP_114082181.1|88601_89060_+|HNH-endonuclease	unknown	unknown	gnl|CDD|366837
NZ_CP046704.1|WP_114082168.1|68236_69199_+|DevR-family-CRISPR-associated-autoregulator	cas7	pfam01905_cas7_CAS-I	gnl|CDD|376656
NZ_CP046704.1|WP_114082169.1|69179_69950_+|hypothetical-protein	cas5	cls000048_cas5_CAS-I-A	unknown
NZ_CP046704.1|WP_114082176.1|81884_82586_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|271000
NZ_CP046704.1|WP_114082179.1|83926_84388_-|cupin-domain-containing-protein	unknown	unknown	gnl|CDD|226357
NZ_CP046704.1|WP_114082173.1|72666_72960_+|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187856
NZ_CP046704.1|WP_114082175.1|78936_79926_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|224343
NZ_CP046704.1|WP_114082177.1|82702_82918_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046704.1|WP_114082171.1|70980_71580_+|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl|CDD|273040
NZ_CP046704.1|WP_114082167.1|66408_68244_+|hypothetical-protein	cas8a4	cls000706_cas8a4_CAS-I-A	unknown
NZ_CP046704.1|WP_159402624.1|80205_80346_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046704.1|WP_114082174.1|75214_76366_+|CRISPR-associated-endoribonuclease-Cas6	cas6	COG5551_cas6_CAS-III	gnl|CDD|227838
NZ_CP046704.1|WP_114082165.1|63406_64033_+|DEAD/DEAH-box-helicase-family-protein	cas3	COG1203_cas3_CAS-I	gnl|CDD|214692
NZ_CP046704.1|WP_114082198.1|86191_88087_+|DUF3370-family-protein	unknown	unknown	gnl|CDD|314680
NZ_CP046704.1|WP_114082170.1|69927_70953_+|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	pfam10040_cas6_CAS-III:CAS-IV	gnl|CDD|337605
NZ_CP046704.1|WP_114082197.1|84987_86073_+|WD40-repeat-domain-containing-protein	unknown	unknown	gnl|CDD|238121
NZ_CP046704.1|WP_114082172.1|71659_72637_+|type-I-D-CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|274976
NZ_CP046704.1|WP_159402625.1|83160_83565_+|ATP-dependent-DNA-helicase	unknown	unknown	unknown
NZ_CP046704.1|WP_114082166.1|64013_66059_+|CRISPR-associated-helicase-Cas3'	cas3	COG1203_cas3_CAS-I	gnl|CDD|224124
NZ_CP046704.1|WP_114082180.1|88365_88605_+|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP046704.1|WP_114082174.1|75214_76366_+|CRISPR-associated-endoribonuclease-Cas6	cas6	COG5551_cas6_CAS-III	2.8e-73	241.4	0.2
NZ_CP046704.1|WP_114082168.1|68236_69199_+|DevR-family-CRISPR-associated-autoregulator	cas7	pfam01905_cas7_CAS-I	2.8e-46	152.4	0.0
NZ_CP046704.1|WP_114082169.1|69179_69950_+|hypothetical-protein	cas5	cls000048_cas5_CAS-I-A	1.1e-88	291.5	0.0
NZ_CP046704.1|WP_114082170.1|69927_70953_+|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	pfam10040_cas6_CAS-III:CAS-IV	6.7e-23	76.3	0.0
NZ_CP046704.1|WP_114082165.1|63406_64033_+|DEAD/DEAH-box-helicase-family-protein	cas3	COG1203_cas3_CAS-I	7.7e-26	85.2	0.6
NZ_CP046704.1|WP_114082172.1|71659_72637_+|type-I-D-CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	6.2e-103	338.8	0.0
NZ_CP046704.1|WP_114082173.1|72666_72960_+|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	1.6e-25	83.8	0.0
NZ_CP046704.1|WP_114082166.1|64013_66059_+|CRISPR-associated-helicase-Cas3'	cas3	COG1203_cas3_CAS-I	7.4e-41	134.9	0.1
NZ_CP046704.1|WP_114082171.1|70980_71580_+|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	9e-35	115.1	0.3
NZ_CP046704.1|WP_114082167.1|66408_68244_+|hypothetical-protein	cas8a4	cls000706_cas8a4_CAS-I-A	5.8e-34	112.0	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046704.1|WP_114082168.1|68236_69199_+|DevR-family-CRISPR-associated-autoregulator	gnl|CDD|376656	pfam01905, DevR, CRISPR-associated negative auto-regulator DevR/Csa2. This group of families is one of several protein families that are always found associated with prokaryotic CRISPRs, themselves a family of clustered regularly interspaced short palindromic repeats, DNA repeats found in nearly half of all bacterial and archaeal genomes. These DNA repeat regions have a remarkably regular structure: unique sequences of constant size, called spacers, sit between each pair of repeats. It has been shown that the CRISPRs are virus-derived sequences acquired by the host to enable them to resist viral infection. The Cas proteins from the host use the CRISPRs to mediate an antiviral response. After transcription of the CRISPR, a complex of Cas proteins termed Cascade cleaves a CRISPR RNA precursor in each repeat and retains the cleavage products containing the virus-derived sequence. Assisted by the helicase Cas3, these mature CRISPR RNAs then serve as small guide RNAs that enable Cascade to interfere with virus proliferation. Cas5 contains an endonuclease motif, whose inactivation leads to loss of resistance, even in the presence of phage-derived spacers. This family used to be known as DUF73. DevR appears to be negative auto-regulator within the system.	1.45787e-60
NZ_CP046704.1|WP_114082176.1|81884_82586_+|serine/threonine-protein-kinase	gnl|CDD|271000	cd14098, STKc_Rad53_Cds1, Catalytic domain of the yeast Serine/Threonine Kinases, Rad53 and Cds1. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. Rad53 and Cds1 are the checkpoint kinase 2 (Chk2) homologs found in budding and fission yeast, respectively. They play a central role in the cell's response to DNA lesions to prevent genome rearrangements and maintain genome integrity. They are phosphorylated in response to DNA damage and incomplete replication, and are essential for checkpoint control. They help promote DNA repair by stalling the cell cycle prior to mitosis in the presence of DNA damage. The Rad53/Cds1 subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	0.00289965
NZ_CP046704.1|WP_114082179.1|83926_84388_-|cupin-domain-containing-protein	gnl|CDD|226357	COG3837, COG3837, Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown].	8.04873e-62
NZ_CP046704.1|WP_114082173.1|72666_72960_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.62838e-26
NZ_CP046704.1|WP_114082175.1|78936_79926_+|helix-turn-helix-domain-containing-protein	gnl|CDD|224343	COG1426, COG1426, Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown].	4.36209e-20
NZ_CP046704.1|WP_114082171.1|70980_71580_+|CRISPR-associated-protein-Cas4	gnl|CDD|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	1.21624e-34
NZ_CP046704.1|WP_114082174.1|75214_76366_+|CRISPR-associated-endoribonuclease-Cas6	gnl|CDD|227838	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	1.78779e-58
NZ_CP046704.1|WP_114082165.1|63406_64033_+|DEAD/DEAH-box-helicase-family-protein	gnl|CDD|214692	smart00487, DEXDc, DEAD-like helicases superfamily.	1.33515e-23
NZ_CP046704.1|WP_114082198.1|86191_88087_+|DUF3370-family-protein	gnl|CDD|314680	pfam11850, DUF3370, Protein of unknown function (DUF3370). This family of proteins are functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 452 to 532 amino acids in length.	0
NZ_CP046704.1|WP_114082170.1|69927_70953_+|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	gnl|CDD|337605	pfam10040, CRISPR_Cas6, CRISPR-associated endoribonuclease Cas6. Cas6 is a member of the RAMP (repeat-associated mysterious protein) superfamily. It is among the most widely distributed Cas proteins and is found in both bacteria and archaea. Cas6 functions in the generation of CRISPR-derived guide RNAs for invader defense in prokaryotes.	2.06948e-13
NZ_CP046704.1|WP_114082197.1|84987_86073_+|WD40-repeat-domain-containing-protein	gnl|CDD|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	1.07467e-54
NZ_CP046704.1|WP_114082172.1|71659_72637_+|type-I-D-CRISPR-associated-endonuclease-Cas1	gnl|CDD|274976	TIGR04093, hypothetical_protein_L8106_25395, CRISPR-associated endonuclease Cas1, subtype CYANO. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes a clade of Cas1 limited to the CYANO subtype of CRISPR/Cas system and most often the type found there.	5.17419e-148
NZ_CP046704.1|WP_114082166.1|64013_66059_+|CRISPR-associated-helicase-Cas3'	gnl|CDD|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	6.33476e-29
NZ_CP046704.1|WP_114082181.1|88601_89060_+|HNH-endonuclease	gnl|CDD|366837	pfam01844, HNH, HNH endonuclease. His-Asn-His (HNH) proteins are a very common family of small nucleic acid-binding proteins that are generally associated with endonuclease activity.	9.67964e-12

Protein sequences

>NZ_CP046704.1|WP_114082174.1|75214_76366_+|CRISPR-associated-endoribonuclease-Cas6
MPRAASSTSGKPKPKQKSVASVVTWADETELVGLVFELESTASALLYSQYTIGLHAWFLEQVRQFDPDLSAYLHDGESEKPFNISALSGQLIASGKQLRLEGNQIYYWYVNVLSQRVAKFLKHWLTQLPERLDLKGASLQIKQVSIAYAPTTYKQLLESSTDRPSSISLSFISPTSFRRKGNHFPLPVPENLFHSYLRRWNDFSSMPAEQESFLKWIDEGVIIHQHRLKSEKVAAGKRGSVTGFTGAISLGLTKAASANFEFSELFYALVRLAPYCGTGHKTTFGLGQTRLDWVEQETSKSIQLITNLLGERIEELIKLFTAQRKRTGGERTDKIAVTWATILARREMGESLKAIAEDLEMPISTVKTYVKLARKSLKQESNS
>NZ_CP046704.1|WP_114082173.1|72666_72960_+|CRISPR-associated-endonuclease-Cas2
MTTLFYLIIYDLPDNKAANKRRTRLHKMLSGYGKWTQYSVFECFLTAIQFATLQTKIEKLVKPEEDSVRLYILDAGAIKRTITYGSEIPRQEQTIVL
>NZ_CP046704.1|WP_114082172.1|71659_72637_+|type-I-D-CRISPR-associated-endonuclease-Cas1
MSVLYVTQADAVLSKNYEAFNVALKQSDGSWKKQTVAAQTVEQVVLMGNPQVTGDALVYALELGMPVHYLSSFGKYLGSALPGYSRNGQLRLAQYKLYSDPVGRLELVKAIVTAKIHNQYQVLYRHNERDNPLKERKSLVKSQKTIDQVRGIEGLAAREYFACWPRMVGKQWTFTGRNRRPPTDPVNSLLSFAYGLLRVQVTAAVHVAGLDPYIGYLHEVHHGQPAMVLDLMEEFRSLIADNVVLAVLHKHEIQPDDFNESLGAYRLKDSARKTFLQAFERKMNDEFKHPVFEYRCTYRRAIELQARLLGRHLQEGIPYKAFALR
>NZ_CP046704.1|WP_114082171.1|70980_71580_+|CRISPR-associated-protein-Cas4
MNEDYLPLAYLNAWEYCPRRFYLEYVLGEMSDNEHIILGRHIHRNINEEGTLQEGEMLIHQQQWVWSDRLKVAGIIDAVEECDGQLVPVEYKKGKMAQHLNDHFQLCAAALCLEERTGRCLAYGEIFYHTNRRRQTVAFTPQLRQMTEQAIVLAQLASQTTMPVPIDNTKKCLSCSLKEICLPFEVKQLRVSMTSETED
>NZ_CP046704.1|WP_114082170.1|69927_70953_+|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6
MICTKDTEVTFAGLSIVLKQVETSISPTPLNSWLSETQLLPVWIPLRINGGVTKIMPVLPSSVLYSNLMQSICQQIAQNTLVEWWQKPYELTGVEVDSDALHVIQVSVTSAASLPALGRAIHAQCFQWFANADTALAEHLHQQNTLPLTAAMQYVSPQKMQLRITLLKKELLAPLLWGLSTNLGESIMLAGIPCQLGKWIDIVQVSSFEKLLQVTTQSVIELRFLSPTSFKQNRGVQSFPLPELVFNSLLRRWNIFAPPEQQFPEVEWNGLVSAYDLKTHALKMEGGAEIGAQGWVKYRFLDSQQARIATILAHFATFAGVGRKTAMGMGQVRLVESRLRG
>NZ_CP046704.1|WP_114082169.1|69179_69950_+|hypothetical-protein
MPKPSNKSKSSLSKQEQQVKVNSNQWLTLTYQPVSLFSLKRSDATSMAARSNLVPTPYAIKMALLKVLLESQGRQHQSNFDQWIKSEFTWIRDLQIYIWPPEQLVVNRNGYKLRYYDQTADKADKSRTTLPMQGGFVFREWVHLQGHLQICCGGCDRLAELERLFAQINYFGKRGCFFQYLPEYKQETSEPLFQPNLITGFTAQLMDDLGEKATFNRINPFSTEKAQLDKDRVIKPGFLPLRLVATSARYDMYQRY
>NZ_CP046704.1|WP_114082168.1|68236_69199_+|DevR-family-CRISPR-associated-autoregulator
MTNTHFPVHSISVSGTLSWQLHALNNEGNEGNQSLTRRYYIIQKDMTEPEYVNGVSGDMLKHIQAEHLHRIAIQEGLTLSEGGKQFHPDRIGYDLEKGLPVFTQSNTDLTAKTNQVLQLCTISDLEGFMVTVKGGQTLKRESVIEFGAAVGLPTLVKTQSYFHAKYGTDNPTPYNVQVNSGLYATVLNIEAFRIGYNPHNFSYSIDPIERKKRLDVLLKSVLYTYLQPNGAKRNTHLPHPDHFEGVITVSTRRCPAPMLSPLSASYSRQIHSLADTLNNLNGAGTIHCFDFETIAQFAEQIQTLIERSQPWESNNAEAIE
>NZ_CP046704.1|WP_114082167.1|66408_68244_+|hypothetical-protein
MTERLFITKKFGTYADTFLMLGLVQLVEYALKATNQKIDIQLVDEGTRYCIQLKKAVNLEPIGKLSYTNPFPPVKGKKTDISKISQETIIFDTVEQSDARKLYRDYVFQQRGKVQFHEDAPDPPHPSTQNGVVLTSMRHDRNHNELWQLGWQNKDDYGILLVTLFQAFSQENYSSLNGETKQVAELFKQATGRQLPSEASAVKVYLPTSVQGVNRIKADSNKVDSQKADWLTLWLIAGGLFSFGVAERVKIAERVYDWRVVALEPLDIQLSKYREVLDKLRKYNPPSGGYGIARFDAELVLRFCQQLLNSHPSQADAELDDFDLWQPINHFVSNFVGTHFGSKGQVYGVKEVFTLGLPGWIRPENSEELTDYLKVLNEHLFVIGSLSAEEGHSELLAAYRDFITGTNLRRFFRFQASYADYIVKRLADPKAKPPRLFSIAGLNTMTKKDTDFTKITTDPSFLRIAKAINQATVYAGKVKTQQGVIELDWQRTYGLAQRLSSQSGSKKDFLSEITDFLAKYQAENLRLSEQLLKEGKSLRRVWTTKEDLDRLVELVENYDTVLVANLLIAYGYARWTKAKEVDLEDENADINDEQDLNNLEPTENLGESNND
>NZ_CP046704.1|WP_114082166.1|64013_66059_+|CRISPR-associated-helicase-Cas3'
MEIIQVEDADLQAIEGDRCRTFQAVSHPLNASVILDDIRAYQRKRVIIICNTVSQAQGLFRDLEELNYEGILHVTLLHSRFLPEHRAQKETDLKSIFAQSWQDDGNCYVLISTQVIEAGINITCQVMHTQLCPMNSLLQRAGRCARFGGEQGEVYIYPTVEVNAASCKIAIADLELEEESAPKKQSFLPYPQETCELTWSVLQEHTQSVQANENVGFRTEEQWINQVHTREDLLQQQRRLNNRMNFEQRFEDAFFRGDQSAGRELIRSIDSRSVFIWEEDGLIDIEEEVVDPQKLLSFSLPVSMLCKVWREFQNMEFGADWIFKQIENPKGKAETYSQPVCTPIKSREALIGSIRILVNPRYVHYDEHIGLLIGIDVFGNHFVSPDKSKRVIASEYRYNMDNYVGHLVLMWKCWREVFTVNRLKNGVSQETTFTSVRDELLAAGGRFIRGKIFPQTQEKEAEALFEMLVFLAIFTHDLGKLQVKWQEVMQGWQAIAHSSFSGRNPGKHLLAHTDYSPEDRHQRDALKDYEKKHKRPNHAVESAYLAQDILKQSLVPLLQDNFLADIEQIKYICHTVIMAAGRHHSAWAGGWDQAATAKIKSIELHPGAKQAIADSWRSIHRFLPQPLSLAKANLGKDVYPIKKDFDLNRFTPDQTEYLQLYLLIVRALRLCDQRSVQLHNI
>NZ_CP046704.1|WP_114082165.1|63406_64033_+|DEAD/DEAH-box-helicase-family-protein
MISEYFQTLTTFPPRNFQREAIAKLLQRQDILLRAPTGSGKTETAIAPFLFAKALNIDFPNKLIYVVPLRTLANSLRQRAEILIANWEKVYPSSHFLAVTLQTGENPEDPRFEGDIVFCTIDQMLSSFLNIPYSVGRGSANVNSGAIFASYLVFDELHLLDPDRSFATVLKVLQQVKGISPFLLMTATLTNELATQIQTLVNNGNYSS
>NZ_CP046704.1|WP_114082175.1|78936_79926_+|helix-turn-helix-domain-containing-protein
MVTTPVYYLQFLDNPNIEISQDELRSLLGEIEVQLHRSRVYRRALAIVQKLIGEQTDQAQDLLKAVGREAIGLAFQRFAQQSQKVETVTDNKQATETVNSSPEIQQEHCALREEPSKNTAENSLWKKTLQLLNHQRISQAELAEQAELAAQQRMVCLRQIGQQLQKTRQSKGLSLDHIQLSTHIRTELIEALENGNWKELSDDIFVRGFIRRYGDALGLNGVALAASLPFLAAIPVTQPFSDQSKKGGGLEIRPTHLYIGYTALLAGAMGGLTLMSQQQANTNISIEQDNSSSAFQSLKQQSPTVKPGIKYTNTGVAVGSDIFPPEGLY
>NZ_CP046704.1|WP_159402624.1|80205_80346_-|hypothetical-protein
MLLFVGGGENATPNSPPQASLSQAGLWAGCDRSLSVSPSPIEENQR
>NZ_CP046704.1|WP_114082176.1|81884_82586_+|serine/threonine-protein-kinase
MDKLLPEQLVKSIYQELLPRLQIESVNPRNPIQVSYLPQPWQLLGKGNYAAVVFHPDYPECVVKIYAPGRLGFEEEVEVYRRLGSHPAFSECLYAKDNFLILKRLYGTTLYDCMHLGLPIPQQVIRDIDKALDYARSRGLHPHDVHGRNVMMHQGRGLVVDISDFLHPEACSKWNHLKKAYYWLYRPVLRPLGLRVPYSALNMLRKSYRLATSFKISCCQLVLRLTRFKYLKL
>NZ_CP046704.1|WP_114082177.1|82702_82918_-|hypothetical-protein
MNNQPNHENLSPQETPCPICGSQNFVWGRTVGESVSQWVYFRADGAGWGEGEKLRARKCRDCNNVQLFSYD
>NZ_CP046704.1|WP_159402625.1|83160_83565_+|ATP-dependent-DNA-helicase
MQNILAIYKLSKTRIKGYMNRLKSLLLGGLLASVSIAALSTHANASVVNFRNEHLNTNTIAFNNAKLIRERQLHEQQAREQKARELRERQVREQKARELRERQAREQKARELRERQAREQKARELRERQARFHH
>NZ_CP046704.1|WP_114082179.1|83926_84388_-|cupin-domain-containing-protein
MTVITPDRLVVEESPSHAAHEPNRTLWISEAGGLTLFGAFIEVLQPGSRSSIKHWHRAEDEMVYVLEGEITLIEGDTKTVLRPGDAATFQAGVAVGHFLENRSALATRCLVVGNRAAVDTITYPDLDRVCHRDRSLPDDIWTNSLGEPAPSPY
>NZ_CP046704.1|WP_114082197.1|84987_86073_+|WD40-repeat-domain-containing-protein
MTMKLPILFKTLTLLSFFLPIPFSMIANVPVIANTLNTPTNTEQPKRLKRTLSGHTAPVRALTLSPSGQVLASGSDDKTIKLWNATTGALLYTLTGHREGIKSIVFTPDEQTLISTSFDNTIKFWNTQTGKEVCTISEKTGVKAMLLTLDGQTLISGSGDNTIKFRNLKTRKIDRILKAETTALAITPDGKTLLSGGENGGRIRVWSLVTGKQIGSFTPPLPKKEDLISGSERASAPITLAVSKDGKMLLCGGYDDSFQSGGVRSTDGKGFKAWDLKTGKLVHDLSFGTSIDALIISPDSKTFIAGGLGREIILRDIKTGKSVMELTGHAGGIYGLAISSDGKILYSGSGDKSVKVWQIKV
>NZ_CP046704.1|WP_114082198.1|86191_88087_+|DUF3370-family-protein
MLLKKTLLVVFLLTLSTPNALAFSDTESYWAKHCIQQLKERKLITGYPDGSFRPETTVTRAQAAVLMLNAFPDSPVKRTAASFKDVPADYWANKAISTAYQKGFFSGYPGGIFQPNQPIPRAQIIGVVAAGKNYSPLPSPMQTLQQYFNDVGQIPNYAQNAIASATINSIVVNYPNVKQLKPLQSATRGEVAALMCRALNIYTVPPQYIAGVEVDSQEIRPLPGKLDLIPTFNSNSPELVTTEGILLSTFPPDGKQVHEAHLNYPFEGRFDIFAHHIVRAETPAQSLTVYQGIIVHNPGNEPVTVQVLQAASYLTKEAQFIALADMVENPQGTVYSGPGDRTMNDVLRGVRQEIFPEKLVIEPKETKILANLPIQVQAPSSNGRTTMMRLTSSSPVYIANLVKNSNISPTLGEWQELLDTGSLAGKRDPIPTPLDPPREPTVFSRVAGVSQGTQWKTQITDNSNVSELTIPSPGKAFSYPLGTVHLITLSTGQIQSAAMLKRYPDTAYFAHSNYGVEYNLTLPLRNITSETQTITVSIQTPVKDEGGTDRLLFLKPGVEQIFFRGTVRVRYIDDNGVEKTRYVHLVQRRGQRGEPLVTLKMLASEKRQVQIDFLYPPDSTPPQVLTVRTKR
>NZ_CP046704.1|WP_114082180.1|88365_88605_+|hypothetical-protein
MITQMMVQPSFWVESGIKLSKVRDIHLFKFTEELQSRLEELSEKKKAGLLTTEEDAELAGILELDRIFTLLNAKIISES
>NZ_CP046704.1|WP_114082181.1|88601_89060_+|HNH-endonuclease
MTVNDSTKKLVRQRAKFLCEYCHSSEEASAALFSIDHIIPQSLKGSDDPDNLALACQRCNGYRYNFTTGIDPDTGQMLPLFNPRQQKWSDHFIWSGDGLKIIGISSVGRATSNRLDLNDERHNEGSIVKARRLWLKGGWHPPDEDPRQVQEF

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP046704_4	4.11|77475|35|NZ_CP046704|CRISPRCasFinder,CRT	77475-77509	35	NZ_CP046703.1	6025388-6025422	0	1.0

1. spacer 4.11|77475|35|NZ_CP046704|CRISPRCasFinder,CRT matches to position: 6025388-6025422, mismatch: 0, identity: 1.0

gctagaggcgatcgctatctatactcgcctccaac	CRISPR spacer
gctagaggcgatcgctatctatactcgcctccaac	Protospacer
***********************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP046704_1	1.1|40798|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	40798-40834	37	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	40798-40834	0	1.0
NZ_CP046704_1	1.2|40872|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	40872-40905	34	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	40872-40905	0	1.0
NZ_CP046704_1	1.3|40943|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	40943-40976	34	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	40943-40976	0	1.0
NZ_CP046704_1	1.4|41014|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	41014-41049	36	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	41014-41049	0	1.0
NZ_CP046704_1	1.5|41087|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	41087-41121	35	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	41087-41121	0	1.0
NZ_CP046704_1	1.6|41159|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	41159-41193	35	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	41159-41193	0	1.0
NZ_CP046704_1	1.7|41231|38|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	41231-41268	38	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	41231-41268	0	1.0
NZ_CP046704_1	1.8|41306|43|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	41306-41348	43	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	41306-41348	0	1.0
NZ_CP046704_1	1.9|41386|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	41386-41422	37	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	41386-41422	0	1.0
NZ_CP046704_1	1.10|41460|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	41460-41496	37	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	41460-41496	0	1.0
NZ_CP046704_1	1.11|41534|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	41534-41569	36	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	41534-41569	0	1.0
NZ_CP046704_1	1.12|41607|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	41607-41642	36	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	41607-41642	0	1.0
NZ_CP046704_1	1.13|41680|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	41680-41715	36	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	41680-41715	0	1.0
NZ_CP046704_1	1.14|41753|41|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	41753-41793	41	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	41753-41793	0	1.0
NZ_CP046704_1	1.15|41831|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	41831-41866	36	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	41831-41866	0	1.0
NZ_CP046704_1	1.16|41904|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	41904-41939	36	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	41904-41939	0	1.0
NZ_CP046704_1	1.17|41977|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	41977-42011	35	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	41977-42011	0	1.0
NZ_CP046704_1	1.18|42049|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	42049-42084	36	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	42049-42084	0	1.0
NZ_CP046704_1	1.19|42122|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	42122-42156	35	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	42122-42156	0	1.0
NZ_CP046704_1	1.20|42194|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	42194-42230	37	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	42194-42230	0	1.0
NZ_CP046704_1	1.21|42268|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	42268-42304	37	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	42268-42304	0	1.0
NZ_CP046704_1	1.22|42342|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	42342-42377	36	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	42342-42377	0	1.0
NZ_CP046704_1	1.23|42415|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	42415-42451	37	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	42415-42451	0	1.0
NZ_CP046704_1	1.24|42489|38|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	42489-42526	38	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	42489-42526	0	1.0
NZ_CP046704_1	1.25|42564|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	42564-42599	36	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	42564-42599	0	1.0
NZ_CP046704_2	2.1|43807|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	43807-43842	36	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	43807-43842	0	1.0
NZ_CP046704_2	2.2|43880|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	43880-43915	36	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	43880-43915	0	1.0
NZ_CP046704_2	2.3|43953|38|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	43953-43990	38	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	43953-43990	0	1.0
NZ_CP046704_2	2.4|44028|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	44028-44061	34	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	44028-44061	0	1.0
NZ_CP046704_2	2.5|44099|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	44099-44134	36	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	44099-44134	0	1.0
NZ_CP046704_2	2.6|44172|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	44172-44205	34	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	44172-44205	0	1.0
NZ_CP046704_2	2.7|44243|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	44243-44277	35	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	44243-44277	0	1.0
NZ_CP046704_2	2.8|44315|39|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	44315-44353	39	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	44315-44353	0	1.0
NZ_CP046704_2	2.9|44391|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	44391-44427	37	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	44391-44427	0	1.0
NZ_CP046704_2	2.10|44465|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	44465-44499	35	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	44465-44499	0	1.0
NZ_CP046704_2	2.11|44537|38|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	44537-44574	38	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	44537-44574	0	1.0
NZ_CP046704_2	2.12|44612|39|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	44612-44650	39	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	44612-44650	0	1.0
NZ_CP046704_2	2.13|44688|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	44688-44724	37	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	44688-44724	0	1.0
NZ_CP046704_2	2.14|44762|43|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	44762-44804	43	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	44762-44804	0	1.0
NZ_CP046704_2	2.15|44842|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	44842-44878	37	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	44842-44878	0	1.0
NZ_CP046704_2	2.16|44916|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	44916-44951	36	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	44916-44951	0	1.0
NZ_CP046704_2	2.17|44989|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	44989-45025	37	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	44989-45025	0	1.0
NZ_CP046704_2	2.18|45063|38|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	45063-45100	38	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	45063-45100	0	1.0
NZ_CP046704_2	2.19|45138|41|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	45138-45178	41	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	45138-45178	0	1.0
NZ_CP046704_2	2.20|45216|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	45216-45249	34	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	45216-45249	0	1.0
NZ_CP046704_2	2.21|45287|36|NZ_CP046704|CRISPRCasFinder,CRT	45287-45322	36	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	45287-45322	0	1.0
NZ_CP046704_3	3.1|73217|38|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	73217-73254	38	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	73217-73254	0	1.0
NZ_CP046704_3	3.2|73292|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	73292-73328	37	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	73292-73328	0	1.0
NZ_CP046704_3	3.3|73366|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	73366-73401	36	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	73366-73401	0	1.0
NZ_CP046704_3	3.4|73439|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	73439-73472	34	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	73439-73472	0	1.0
NZ_CP046704_3	3.5|73510|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	73510-73544	35	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	73510-73544	0	1.0
NZ_CP046704_3	3.6|73582|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	73582-73618	37	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	73582-73618	0	1.0
NZ_CP046704_3	3.7|73656|42|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	73656-73697	42	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	73656-73697	0	1.0
NZ_CP046704_3	3.8|73735|40|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	73735-73774	40	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	73735-73774	0	1.0
NZ_CP046704_3	3.9|73812|38|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	73812-73849	38	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	73812-73849	0	1.0
NZ_CP046704_3	3.10|73887|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	73887-73923	37	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	73887-73923	0	1.0
NZ_CP046704_3	3.11|73961|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	73961-73995	35	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	73961-73995	0	1.0
NZ_CP046704_3	3.12|74033|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	74033-74068	36	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	74033-74068	0	1.0
NZ_CP046704_3	3.13|74106|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	74106-74140	35	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	74106-74140	0	1.0
NZ_CP046704_3	3.14|74178|42|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	74178-74219	42	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	74178-74219	0	1.0
NZ_CP046704_3	3.15|74257|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	74257-74292	36	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	74257-74292	0	1.0
NZ_CP046704_3	3.16|74330|38|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	74330-74367	38	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	74330-74367	0	1.0
NZ_CP046704_3	3.17|74405|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	74405-74441	37	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	74405-74441	0	1.0
NZ_CP046704_3	3.18|74479|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	74479-74513	35	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	74479-74513	0	1.0
NZ_CP046704_3	3.19|74551|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	74551-74584	34	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	74551-74584	0	1.0
NZ_CP046704_3	3.20|74622|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	74622-74658	37	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	74622-74658	0	1.0
NZ_CP046704_3	3.21|74696|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	74696-74732	37	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	74696-74732	0	1.0
NZ_CP046704_3	3.22|74770|38|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	74770-74807	38	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	74770-74807	0	1.0
NZ_CP046704_3	3.23|74845|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	74845-74879	35	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	74845-74879	0	1.0
NZ_CP046704_3	3.24|74917|41|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	74917-74957	41	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	74917-74957	0	1.0
NZ_CP046704_3	3.25|74995|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	74995-75028	34	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	74995-75028	0	1.0
NZ_CP046704_4	4.1|76743|38|NZ_CP046704|CRISPRCasFinder,CRT	76743-76780	38	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	76743-76780	0	1.0
NZ_CP046704_4	4.2|76818|35|NZ_CP046704|CRISPRCasFinder,CRT	76818-76852	35	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	73292-73326	0	1.0
NZ_CP046704_4	4.2|76818|35|NZ_CP046704|CRISPRCasFinder,CRT	76818-76852	35	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	76818-76852	0	1.0
NZ_CP046704_4	4.3|76890|37|NZ_CP046704|CRISPRCasFinder,CRT	76890-76926	37	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	76890-76926	0	1.0
NZ_CP046704_4	4.4|76964|34|NZ_CP046704|CRISPRCasFinder,CRT	76964-76997	34	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	76964-76997	0	1.0
NZ_CP046704_4	4.5|77035|36|NZ_CP046704|CRISPRCasFinder,CRT	77035-77070	36	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	77035-77070	0	1.0
NZ_CP046704_4	4.6|77108|36|NZ_CP046704|CRISPRCasFinder,CRT	77108-77143	36	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	77108-77143	0	1.0
NZ_CP046704_4	4.7|77181|37|NZ_CP046704|CRISPRCasFinder,CRT	77181-77217	37	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	77181-77217	0	1.0
NZ_CP046704_4	4.8|77255|37|NZ_CP046704|CRISPRCasFinder,CRT	77255-77291	37	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	77255-77291	0	1.0
NZ_CP046704_4	4.9|77329|37|NZ_CP046704|CRISPRCasFinder,CRT	77329-77365	37	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	77329-77365	0	1.0
NZ_CP046704_4	4.10|77403|35|NZ_CP046704|CRISPRCasFinder,CRT	77403-77437	35	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	77403-77437	0	1.0
NZ_CP046704_4	4.11|77475|35|NZ_CP046704|CRISPRCasFinder,CRT	77475-77509	35	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	77475-77509	0	1.0
NZ_CP046704_4	4.12|77547|37|NZ_CP046704|CRISPRCasFinder,CRT	77547-77583	37	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	77547-77583	0	1.0
NZ_CP046704_4	4.13|77621|38|NZ_CP046704|CRISPRCasFinder,CRT	77621-77658	38	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	77621-77658	0	1.0
NZ_CP046704_4	4.14|77696|36|NZ_CP046704|CRISPRCasFinder,CRT	77696-77731	36	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	77696-77731	0	1.0
NZ_CP046704_4	4.15|77769|35|NZ_CP046704|CRISPRCasFinder,CRT	77769-77803	35	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	77769-77803	0	1.0
NZ_CP046704_4	4.16|77841|37|NZ_CP046704|CRISPRCasFinder,CRT	77841-77877	37	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	77841-77877	0	1.0
NZ_CP046704_4	4.17|77915|36|NZ_CP046704|CRISPRCasFinder,CRT	77915-77950	36	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	77915-77950	0	1.0
NZ_CP046704_4	4.18|77988|36|NZ_CP046704|CRISPRCasFinder,CRT	77988-78023	36	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	77988-78023	0	1.0
NZ_CP046704_4	4.19|78061|37|NZ_CP046704|CRISPRCasFinder,CRT	78061-78097	37	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	78061-78097	0	1.0
NZ_CP046704_4	4.20|78135|35|NZ_CP046704|CRISPRCasFinder,CRT	78135-78169	35	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	78135-78169	0	1.0
NZ_CP046704_4	4.21|78207|38|NZ_CP046704|CRISPRCasFinder,CRT	78207-78244	38	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	78207-78244	0	1.0
NZ_CP046704_4	4.22|78282|37|NZ_CP046704|CRISPRCasFinder,CRT	78282-78318	37	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	78282-78318	0	1.0
NZ_CP046704_3	3.2|73292|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	73292-73328	37	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	76818-76854	2	0.946
NZ_CP046704_2	2.10|44465|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	44465-44499	35	NZ_CP032858	Bacillus subtilis subsp. subtilis strain 2RL2-3 plasmid unnamed1, complete sequence	136183-136217	7	0.8
NZ_CP046704_2	2.10|44465|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	44465-44499	35	NZ_CP032873	Bacillus subtilis subsp. subtilis strain 2KL1 plasmid unnamed1, complete sequence	13471-13505	7	0.8
NZ_CP046704_2	2.10|44465|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	44465-44499	35	NZ_CP026534	Bacillus velezensis strain DKU_NT_04 plasmid p1_DKU_NT_04, complete sequence	139670-139704	7	0.8
NZ_CP046704_3	3.25|74995|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	74995-75028	34	NC_020287	Synechocystis sp. PCC 6803 plasmid pSYSA_M, complete sequence	76186-76219	7	0.794
NZ_CP046704_3	3.25|74995|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	74995-75028	34	NZ_CP028097	Synechocystis sp. IPPAS B-1465 plasmid pSYSA, complete sequence	78667-78700	7	0.794
NZ_CP046704_3	3.25|74995|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	74995-75028	34	NC_005230	Synechocystis sp. PCC 6803 plasmid pSYSA, complete sequence	78744-78777	7	0.794
NZ_CP046704_3	3.25|74995|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	74995-75028	34	NZ_CP007543	Synechocystis sp. PCC 6714 plasmid pSYLA, complete sequence	67769-67802	7	0.794
NZ_CP046704_3	3.5|73510|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	73510-73544	35	NC_027395	Phage vB_EcoP_SU10, complete genome	74703-74737	8	0.771
NZ_CP046704_1	1.2|40872|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	40872-40905	34	NZ_CP035227	Bacillus subtilis strain SRCM103517 plasmid unnamed1	22335-22368	10	0.706
NZ_CP046704_2	2.9|44391|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	44391-44427	37	CP019152	Acinetobacter lwoffii strain ZS207 plasmid pZS-2, complete sequence	10404-10440	10	0.73
NZ_CP046704_3	3.19|74551|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	74551-74584	34	MK327944	Escherichia phage vB_EcoM_G2540-3, complete genome	33478-33511	10	0.706
NZ_CP046704_3	3.19|74551|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	74551-74584	34	MH243439	Escherichia phage vB_EcoM_NBG2, complete genome	31061-31094	10	0.706
NZ_CP046704_3	3.20|74622|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	74622-74658	37	NZ_CP045341	Vibrio sp. THAF190c plasmid pTHAF190c_c, complete sequence	25413-25449	10	0.73
NZ_CP046704_2	2.20|45216|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	45216-45249	34	MN549360	Rhizobium phage RL38J1, complete genome	99324-99357	12	0.647
NZ_CP046704_3	3.25|74995|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT	74995-75028	34	MK685668	Shigella phage VB_Ship_A7, complete genome	7924-7957	12	0.647

1. spacer 1.1|40798|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

acagctagggtgaagaagctgtatgagttggaagtaa	CRISPR spacer
acagctagggtgaagaagctgtatgagttggaagtaa	Protospacer
*************************************

2. spacer 1.2|40872|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

caatcccaaaatgattggcattgtacaagctttc	CRISPR spacer
caatcccaaaatgattggcattgtacaagctttc	Protospacer
**********************************

3. spacer 1.3|40943|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

cattcaagacatcatgctgggtcaatatttgcga	CRISPR spacer
cattcaagacatcatgctgggtcaatatttgcga	Protospacer
**********************************

4. spacer 1.4|41014|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

cggctaatgctccgattgtattcaaagcttatcctg	CRISPR spacer
cggctaatgctccgattgtattcaaagcttatcctg	Protospacer
************************************

5. spacer 1.5|41087|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

tagtagatgctactagcggtaaatacattaaggtg	CRISPR spacer
tagtagatgctactagcggtaaatacattaaggtg	Protospacer
***********************************

6. spacer 1.6|41159|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

ttagctgctctagctacaactaattctgcttcaga	CRISPR spacer
ttagctgctctagctacaactaattctgcttcaga	Protospacer
***********************************

7. spacer 1.7|41231|38|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

acttgtaagattagttcctgcacctgaaacatcgttag	CRISPR spacer
acttgtaagattagttcctgcacctgaaacatcgttag	Protospacer
**************************************

8. spacer 1.8|41306|43|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

cgatcgcctgccagttttagctgtctcagcctgaagccctccc	CRISPR spacer
cgatcgcctgccagttttagctgtctcagcctgaagccctccc	Protospacer
*******************************************

9. spacer 1.9|41386|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

gcttatcaggaataacagcagttctgaataaacttgg	CRISPR spacer
gcttatcaggaataacagcagttctgaataaacttgg	Protospacer
*************************************

10. spacer 1.10|41460|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

agtttattaaagctacagagaatatgcctatgctgga	CRISPR spacer
agtttattaaagctacagagaatatgcctatgctgga	Protospacer
*************************************

11. spacer 1.11|41534|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

cctcaaaactgggaagaatttgttaatctcaccaca	CRISPR spacer
cctcaaaactgggaagaatttgttaatctcaccaca	Protospacer
************************************

12. spacer 1.12|41607|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

aaacacacgccgattctattcgcggaatggcagaac	CRISPR spacer
aaacacacgccgattctattcgcggaatggcagaac	Protospacer
************************************

13. spacer 1.13|41680|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

cagaacagcaaagatttactctgaatgactcggaac	CRISPR spacer
cagaacagcaaagatttactctgaatgactcggaac	Protospacer
************************************

14. spacer 1.14|41753|41|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

ataagtgggaaaaaccagatgagtatagggaagaatgggta	CRISPR spacer
ataagtgggaaaaaccagatgagtatagggaagaatgggta	Protospacer
*****************************************

15. spacer 1.15|41831|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

catagaggctgggtatgtcgttgcaaacagtgttga	CRISPR spacer
catagaggctgggtatgtcgttgcaaacagtgttga	Protospacer
************************************

16. spacer 1.16|41904|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

acgatgatacacgcaaaaagttattccccaagtatg	CRISPR spacer
acgatgatacacgcaaaaagttattccccaagtatg	Protospacer
************************************

17. spacer 1.17|41977|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

gtttaaagttgctctaccaatagtgtcgtttacga	CRISPR spacer
gtttaaagttgctctaccaatagtgtcgtttacga	Protospacer
***********************************

18. spacer 1.18|42049|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

aagcgggggctagttacggcttggagtgggcattta	CRISPR spacer
aagcgggggctagttacggcttggagtgggcattta	Protospacer
************************************

19. spacer 1.19|42122|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

ctttttgttgttctgctgacacttgttgaattttg	CRISPR spacer
ctttttgttgttctgctgacacttgttgaattttg	Protospacer
***********************************

20. spacer 1.20|42194|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

tttacaaaaaaaactatcttttaactactagcgcatc	CRISPR spacer
tttacaaaaaaaactatcttttaactactagcgcatc	Protospacer
*************************************

21. spacer 1.21|42268|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

aaccatgaatattctgaaaagaatttaataatcccat	CRISPR spacer
aaccatgaatattctgaaaagaatttaataatcccat	Protospacer
*************************************

22. spacer 1.22|42342|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

atcttcttctatctcacatatatctttctctatgta	CRISPR spacer
atcttcttctatctcacatatatctttctctatgta	Protospacer
************************************

23. spacer 1.23|42415|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

catttacataaccaccctcacggtgtaaacggtcttt	CRISPR spacer
catttacataaccaccctcacggtgtaaacggtcttt	Protospacer
*************************************

24. spacer 1.24|42489|38|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

cgttttggacactacagggatataactaaaaaaagaat	CRISPR spacer
cgttttggacactacagggatataactaaaaaaagaat	Protospacer
**************************************

25. spacer 1.25|42564|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

actcaagatatgctcatgagggcatttaatgaagac	CRISPR spacer
actcaagatatgctcatgagggcatttaatgaagac	Protospacer
************************************

26. spacer 2.1|43807|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

atgtcatagattacttctggtagtgcaaaatcatga	CRISPR spacer
atgtcatagattacttctggtagtgcaaaatcatga	Protospacer
************************************

27. spacer 2.2|43880|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

attgaacagtgtcgaattctctcgcacttagtaggc	CRISPR spacer
attgaacagtgtcgaattctctcgcacttagtaggc	Protospacer
************************************

28. spacer 2.3|43953|38|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

ctttagcggcagatattagttcgcggatatcggctgcg	CRISPR spacer
ctttagcggcagatattagttcgcggatatcggctgcg	Protospacer
**************************************

29. spacer 2.4|44028|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

tcgctatagaggtaagcgatcgccatctcaaaac	CRISPR spacer
tcgctatagaggtaagcgatcgccatctcaaaac	Protospacer
**********************************

30. spacer 2.5|44099|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

acaagtagtccgtatactgttcctgggtcgtttatc	CRISPR spacer
acaagtagtccgtatactgttcctgggtcgtttatc	Protospacer
************************************

31. spacer 2.6|44172|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

ccaccataatcgagccaatttacatcaccggagg	CRISPR spacer
ccaccataatcgagccaatttacatcaccggagg	Protospacer
**********************************

32. spacer 2.7|44243|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

tagtgtttacaaacaagttctagacttatctagaa	CRISPR spacer
tagtgtttacaaacaagttctagacttatctagaa	Protospacer
***********************************

33. spacer 2.8|44315|39|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

ttgttttggcgatgagttgcacagggcgcaccaccaaca	CRISPR spacer
ttgttttggcgatgagttgcacagggcgcaccaccaaca	Protospacer
***************************************

34. spacer 2.9|44391|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

ttaaacataatttaatatctcttataaataatagtga	CRISPR spacer
ttaaacataatttaatatctcttataaataatagtga	Protospacer
*************************************

35. spacer 2.10|44465|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

aaataaatgctgttactttgatttaatatatcaac	CRISPR spacer
aaataaatgctgttactttgatttaatatatcaac	Protospacer
***********************************

36. spacer 2.11|44537|38|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

acttctgcatccatcagtgcaacttgagcaacaaagta	CRISPR spacer
acttctgcatccatcagtgcaacttgagcaacaaagta	Protospacer
**************************************

37. spacer 2.12|44612|39|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

acgctatagctactaaagctaaagctgaacaaatggggg	CRISPR spacer
acgctatagctactaaagctaaagctgaacaaatggggg	Protospacer
***************************************

38. spacer 2.13|44688|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

gtaaagagctaaccaaagctaatttagttattcaata	CRISPR spacer
gtaaagagctaaccaaagctaatttagttattcaata	Protospacer
*************************************

39. spacer 2.14|44762|43|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

aataaatcctgatagctactgagtaccgcgcctgcgccgctaa	CRISPR spacer
aataaatcctgatagctactgagtaccgcgcctgcgccgctaa	Protospacer
*******************************************

40. spacer 2.15|44842|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

cgaagctttgggatgactacctcaaaaagccaatctt	CRISPR spacer
cgaagctttgggatgactacctcaaaaagccaatctt	Protospacer
*************************************

41. spacer 2.16|44916|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

aggttgatactgtgaatagggcttttcaccgggtac	CRISPR spacer
aggttgatactgtgaatagggcttttcaccgggtac	Protospacer
************************************

42. spacer 2.17|44989|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

gtcgaatgtaaacaacttaatctgaaaatccacttat	CRISPR spacer
gtcgaatgtaaacaacttaatctgaaaatccacttat	Protospacer
*************************************

43. spacer 2.18|45063|38|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

ctagaatgcggtttgctcaaccaggcaatgacatgaag	CRISPR spacer
ctagaatgcggtttgctcaaccaggcaatgacatgaag	Protospacer
**************************************

44. spacer 2.19|45138|41|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

gaaagaagggccgttacgagaactgccaagataattccagt	CRISPR spacer
gaaagaagggccgttacgagaactgccaagataattccagt	Protospacer
*****************************************

45. spacer 2.20|45216|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

ataaactctgcatcctcgctgttatagaactgag	CRISPR spacer
ataaactctgcatcctcgctgttatagaactgag	Protospacer
**********************************

46. spacer 2.21|45287|36|NZ_CP046704|CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

tggatgcaatcttgagtcattgtgtggtggttgcgt	CRISPR spacer
tggatgcaatcttgagtcattgtgtggtggttgcgt	Protospacer
************************************

47. spacer 3.1|73217|38|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

atattctgaaattcgacggccatccgtcgaagctataa	CRISPR spacer
atattctgaaattcgacggccatccgtcgaagctataa	Protospacer
**************************************

48. spacer 3.2|73292|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

taatagcattgttatgaatatagagaaaaagaaagtg	CRISPR spacer
taatagcattgttatgaatatagagaaaaagaaagtg	Protospacer
*************************************

49. spacer 3.3|73366|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

attaaagagttggctagcgatcgcagaatatgaacg	CRISPR spacer
attaaagagttggctagcgatcgcagaatatgaacg	Protospacer
************************************

50. spacer 3.4|73439|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

caatagttggatctgaaagcatctcaactatttg	CRISPR spacer
caatagttggatctgaaagcatctcaactatttg	Protospacer
**********************************

51. spacer 3.5|73510|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

ttgccagtttcatggtcttctataagcactatggc	CRISPR spacer
ttgccagtttcatggtcttctataagcactatggc	Protospacer
***********************************

52. spacer 3.6|73582|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

attaaacgtgaaacctggattacttgggagaaattag	CRISPR spacer
attaaacgtgaaacctggattacttgggagaaattag	Protospacer
*************************************

53. spacer 3.7|73656|42|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

taaagctgctcaagtccttgggttctgccaaatagctctagg	CRISPR spacer
taaagctgctcaagtccttgggttctgccaaatagctctagg	Protospacer
******************************************

54. spacer 3.8|73735|40|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

aataattgggcaactgcgatcgcaattacaaaaccacaca	CRISPR spacer
aataattgggcaactgcgatcgcaattacaaaaccacaca	Protospacer
****************************************

55. spacer 3.9|73812|38|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

taatcagcacacaaagcacagtttagctttattcctgc	CRISPR spacer
taatcagcacacaaagcacagtttagctttattcctgc	Protospacer
**************************************

56. spacer 3.10|73887|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

aagagattgcctttttcctcaaccctgattaattcaa	CRISPR spacer
aagagattgcctttttcctcaaccctgattaattcaa	Protospacer
*************************************

57. spacer 3.11|73961|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

atatacttttatttttgatgcactcataaaagaag	CRISPR spacer
atatacttttatttttgatgcactcataaaagaag	Protospacer
***********************************

58. spacer 3.12|74033|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

ctacattttttaaagttagactccaatagttagtat	CRISPR spacer
ctacattttttaaagttagactccaatagttagtat	Protospacer
************************************

59. spacer 3.13|74106|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

atttttttcacaccgactgaagcagcaattttaaa	CRISPR spacer
atttttttcacaccgactgaagcagcaattttaaa	Protospacer
***********************************

60. spacer 3.14|74178|42|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

ctccctaaagcaatcttacctttgttagctgtcttttgccag	CRISPR spacer
ctccctaaagcaatcttacctttgttagctgtcttttgccag	Protospacer
******************************************

61. spacer 3.15|74257|36|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

ttgtatgagtaacaacacctatcaaattaatcttgt	CRISPR spacer
ttgtatgagtaacaacacctatcaaattaatcttgt	Protospacer
************************************

62. spacer 3.16|74330|38|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

atactcacgcaggcttgataactggtatcaaggcaatg	CRISPR spacer
atactcacgcaggcttgataactggtatcaaggcaatg	Protospacer
**************************************

63. spacer 3.17|74405|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

ctcacgatgagaaagtggagaagcaagcccgtgctat	CRISPR spacer
ctcacgatgagaaagtggagaagcaagcccgtgctat	Protospacer
*************************************

64. spacer 3.18|74479|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

ttacattcatgcttgtaaacttgtaaaagaattaa	CRISPR spacer
ttacattcatgcttgtaaacttgtaaaagaattaa	Protospacer
***********************************

65. spacer 3.19|74551|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

gttcagaaattttatccttaatgtttttgtttgg	CRISPR spacer
gttcagaaattttatccttaatgtttttgtttgg	Protospacer
**********************************

66. spacer 3.20|74622|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

aagaagaaactcattccattaacaaagttagtccggc	CRISPR spacer
aagaagaaactcattccattaacaaagttagtccggc	Protospacer
*************************************

67. spacer 3.21|74696|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

tatgagatggaaacatcttgtcctttagctaattcct	CRISPR spacer
tatgagatggaaacatcttgtcctttagctaattcct	Protospacer
*************************************

68. spacer 3.22|74770|38|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

cagaacgataagtataaggctggtggtcatatagtacc	CRISPR spacer
cagaacgataagtataaggctggtggtcatatagtacc	Protospacer
**************************************

69. spacer 3.23|74845|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

agagtttttatcagcatcaagcagcatcccaaatg	CRISPR spacer
agagtttttatcagcatcaagcagcatcccaaatg	Protospacer
***********************************

70. spacer 3.24|74917|41|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

attcctttatgagtgattagcgatcgctgagaacttcagag	CRISPR spacer
attcctttatgagtgattagcgatcgctgagaacttcagag	Protospacer
*****************************************

71. spacer 3.25|74995|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

aattaaagttctcagctttagcttgggcaataag	CRISPR spacer
aattaaagttctcagctttagcttgggcaataag	Protospacer
**********************************

72. spacer 4.1|76743|38|NZ_CP046704|CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

gttcaaatgctgtctcttatcaaaatcaagttcgagga	CRISPR spacer
gttcaaatgctgtctcttatcaaaatcaagttcgagga	Protospacer
**************************************

73. spacer 4.2|76818|35|NZ_CP046704|CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

taatagcattgttatgaatatagagaaaaagaaag	CRISPR spacer
taatagcattgttatgaatatagagaaaaagaaag	Protospacer
***********************************

74. spacer 4.2|76818|35|NZ_CP046704|CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

taatagcattgttatgaatatagagaaaaagaaag	CRISPR spacer
taatagcattgttatgaatatagagaaaaagaaag	Protospacer
***********************************

75. spacer 4.3|76890|37|NZ_CP046704|CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

atatctgaatttttcgagactgggaatattcataact	CRISPR spacer
atatctgaatttttcgagactgggaatattcataact	Protospacer
*************************************

76. spacer 4.4|76964|34|NZ_CP046704|CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

aattaactggttgcgcctgctcaacaacaatcga	CRISPR spacer
aattaactggttgcgcctgctcaacaacaatcga	Protospacer
**********************************

77. spacer 4.5|77035|36|NZ_CP046704|CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

accaccggaggcagaaggaaatctggtgatcgtatc	CRISPR spacer
accaccggaggcagaaggaaatctggtgatcgtatc	Protospacer
************************************

78. spacer 4.6|77108|36|NZ_CP046704|CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

taactgctctgccacttcccgatagtcatctgcgat	CRISPR spacer
taactgctctgccacttcccgatagtcatctgcgat	Protospacer
************************************

79. spacer 4.7|77181|37|NZ_CP046704|CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

cccaagagaatattgacgctttagttcatctagaaag	CRISPR spacer
cccaagagaatattgacgctttagttcatctagaaag	Protospacer
*************************************

80. spacer 4.8|77255|37|NZ_CP046704|CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

atcacacgcttggtgataacgcaatactaggactaca	CRISPR spacer
atcacacgcttggtgataacgcaatactaggactaca	Protospacer
*************************************

81. spacer 4.9|77329|37|NZ_CP046704|CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

tcatcttgaaagccacttaccaaagaattggattaag	CRISPR spacer
tcatcttgaaagccacttaccaaagaattggattaag	Protospacer
*************************************

82. spacer 4.10|77403|35|NZ_CP046704|CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

ctgtacttctctaaaaagatggaaattccaggtgg	CRISPR spacer
ctgtacttctctaaaaagatggaaattccaggtgg	Protospacer
***********************************

83. spacer 4.11|77475|35|NZ_CP046704|CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

gctagaggcgatcgctatctatactcgcctccaac	CRISPR spacer
gctagaggcgatcgctatctatactcgcctccaac	Protospacer
***********************************

84. spacer 4.12|77547|37|NZ_CP046704|CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

gggttattaagctttacactaccctttctaaagccat	CRISPR spacer
gggttattaagctttacactaccctttctaaagccat	Protospacer
*************************************

85. spacer 4.13|77621|38|NZ_CP046704|CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

atttttatcgctcagatgcaccatacaaaaacttactg	CRISPR spacer
atttttatcgctcagatgcaccatacaaaaacttactg	Protospacer
**************************************

86. spacer 4.14|77696|36|NZ_CP046704|CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

ttcaatccacgctttcattattccaacaatttatgc	CRISPR spacer
ttcaatccacgctttcattattccaacaatttatgc	Protospacer
************************************

87. spacer 4.15|77769|35|NZ_CP046704|CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

ctacttcggttgtcatagtgtgttagtcgtttttg	CRISPR spacer
ctacttcggttgtcatagtgtgttagtcgtttttg	Protospacer
***********************************

88. spacer 4.16|77841|37|NZ_CP046704|CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

gttccgttacccatgtcaattaatgtccaatccctat	CRISPR spacer
gttccgttacccatgtcaattaatgtccaatccctat	Protospacer
*************************************

89. spacer 4.17|77915|36|NZ_CP046704|CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

ttcgtaagcataccctctgcaatcagacaaaggatg	CRISPR spacer
ttcgtaagcataccctctgcaatcagacaaaggatg	Protospacer
************************************

90. spacer 4.18|77988|36|NZ_CP046704|CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

caaatcaatggttgtctgtgcctgttaataacatta	CRISPR spacer
caaatcaatggttgtctgtgcctgttaataacatta	Protospacer
************************************

91. spacer 4.19|78061|37|NZ_CP046704|CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

tcaaattcaattacttgatgaaactcacccaagacag	CRISPR spacer
tcaaattcaattacttgatgaaactcacccaagacag	Protospacer
*************************************

92. spacer 4.20|78135|35|NZ_CP046704|CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

gcagcagtagctcgcttggatcatccggcagtttg	CRISPR spacer
gcagcagtagctcgcttggatcatccggcagtttg	Protospacer
***********************************

93. spacer 4.21|78207|38|NZ_CP046704|CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

atcatttagtttgattctaaactttccaattgggctgc	CRISPR spacer
atcatttagtttgattctaaactttccaattgggctgc	Protospacer
**************************************

94. spacer 4.22|78282|37|NZ_CP046704|CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 0, identity: 1.0

gaaaaagcggcaatgcgatcgttttcgttagaaaaat	CRISPR spacer
gaaaaagcggcaatgcgatcgttttcgttagaaaaat	Protospacer
*************************************

95. spacer 3.2|73292|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 2, identity: 0.946

taatagcattgttatgaatatagagaaaaagaaagtg	CRISPR spacer
taatagcattgttatgaatatagagaaaaagaaaggt	Protospacer
***********************************  

96. spacer 2.10|44465|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032858 (Bacillus subtilis subsp. subtilis strain 2RL2-3 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.8

aaataaatgctgttactttgatttaatatatcaac	CRISPR spacer
acacaattattgttactttgattttatataacaac	Protospacer
* *.** *..************** ***** ****

97. spacer 2.10|44465|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032873 (Bacillus subtilis subsp. subtilis strain 2KL1 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.8

aaataaatgctgttactttgatttaatatatcaac	CRISPR spacer
acacaattattgttactttgattttatataacaac	Protospacer
* *.** *..************** ***** ****

98. spacer 2.10|44465|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026534 (Bacillus velezensis strain DKU_NT_04 plasmid p1_DKU_NT_04, complete sequence) position: , mismatch: 7, identity: 0.8

aaataaatgctgttactttgatttaatatatcaac	CRISPR spacer
acacaattattgttactttgattttatataacaac	Protospacer
* *.** *..************** ***** ****

99. spacer 3.25|74995|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NC_020287 (Synechocystis sp. PCC 6803 plasmid pSYSA_M, complete sequence) position: , mismatch: 7, identity: 0.794

---aattaaagttctcagctttagcttgggcaataag	CRISPR spacer
tttgattaa---tctcagctttggcttgggtaataat	Protospacer
   .*****   **********.*******.***** 

100. spacer 3.25|74995|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP028097 (Synechocystis sp. IPPAS B-1465 plasmid pSYSA, complete sequence) position: , mismatch: 7, identity: 0.794

---aattaaagttctcagctttagcttgggcaataag	CRISPR spacer
tttgattaa---tctcagctttggcttgggtaataat	Protospacer
   .*****   **********.*******.***** 

101. spacer 3.25|74995|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NC_005230 (Synechocystis sp. PCC 6803 plasmid pSYSA, complete sequence) position: , mismatch: 7, identity: 0.794

---aattaaagttctcagctttagcttgggcaataag	CRISPR spacer
tttgattaa---tctcagctttggcttgggtaataat	Protospacer
   .*****   **********.*******.***** 

102. spacer 3.25|74995|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP007543 (Synechocystis sp. PCC 6714 plasmid pSYLA, complete sequence) position: , mismatch: 7, identity: 0.794

---aattaaagttctcagctttagcttgggcaataag	CRISPR spacer
tttgattaa---tctcagctttggcttgggtaataat	Protospacer
   .*****   **********.*******.***** 

103. spacer 3.5|73510|35|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NC_027395 (Phage vB_EcoP_SU10, complete genome) position: , mismatch: 8, identity: 0.771

ttgccagtttcatggtcttctataagcactatggc----	CRISPR spacer
ttaccagtttcatagtcttctataag----ataggtaca	Protospacer
**.**********.************    **.*     

104. spacer 1.2|40872|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP035227 (Bacillus subtilis strain SRCM103517 plasmid unnamed1) position: , mismatch: 10, identity: 0.706

caatcccaaaatgattggcattgtacaagctttc	CRISPR spacer
tcaccgcaaaatgactggcattgtaaaagccgcg	Protospacer
. *.* ********.********** ****. . 

105. spacer 2.9|44391|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to CP019152 (Acinetobacter lwoffii strain ZS207 plasmid pZS-2, complete sequence) position: , mismatch: 10, identity: 0.73

ttaaacataatttaatatctcttataaataatagtga	CRISPR spacer
attaatttaatttaatatctcttaaaattaatataat	Protospacer
 * **. ***************** ** *****  . 

106. spacer 3.19|74551|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to MK327944 (Escherichia phage vB_EcoM_G2540-3, complete genome) position: , mismatch: 10, identity: 0.706

gttcagaaattttatccttaatgtttttgtttgg-------	CRISPR spacer
attcagaaattttatctttaat-------tttagaaacaac	Protospacer
.***************.*****       ***.*       

107. spacer 3.19|74551|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to MH243439 (Escherichia phage vB_EcoM_NBG2, complete genome) position: , mismatch: 10, identity: 0.706

gttcagaaattttatccttaatgtttttgtttgg-------	CRISPR spacer
attcagaaattttatctttaat-------tttagaaacaac	Protospacer
.***************.*****       ***.*       

108. spacer 3.20|74622|37|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045341 (Vibrio sp. THAF190c plasmid pTHAF190c_c, complete sequence) position: , mismatch: 10, identity: 0.73

aagaagaaactcattccattaacaaagttagtccggc	CRISPR spacer
ttgaagaaactcattcaattaacatagtgaactcgtt	Protospacer
  ************** ******* *** *...** .

109. spacer 2.20|45216|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to MN549360 (Rhizobium phage RL38J1, complete genome) position: , mismatch: 12, identity: 0.647

ataaactctgcatcctcgctgttatagaactgag	CRISPR spacer
cctgtgtctgcttcctcgctgttatcgaaccacc	Protospacer
 . .  ***** ************* ****..  

110. spacer 3.25|74995|34|NZ_CP046704|PILER-CR,CRISPRCasFinder,CRT matches to MK685668 (Shigella phage VB_Ship_A7, complete genome) position: , mismatch: 12, identity: 0.647

aattaaagttctcagctttagcttgggcaataag	CRISPR spacer
tcaggaagttctcagcttcagcttgtgcaccttt	Protospacer
    .*************.****** *** .   

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	58875 : 113321	46	Thermus_phage(16.67%)	transposase,protease	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP046704|58875:113321|DBSCAN-SWA
ATTAAGATAAGCTTAAGCGTTCAGAGAGGATGTGATTAACACTTTCAACATTCCACTGTGCGCCAGAAATTTTAATCCTTAAACCAATTTGTTTAATTGCAGACTCAACGGCACCAGAACCAATAGAACATAATTGTTCAGCCTGATAATAGCTGTAATTGACAATGCGAGGGAGATGCTTTTCCAGATAAGCGATGAAATTTTTAGCTTGTTTACCTCGGCAATAATTAAATAAAGTCTTGGCTGCTTCTACTTGACCTTTCCACAATAAAGTTTCCGCAGCTTTGAGTCGCTTCAAAGAACCACCAACTTTATAAAGATTTTCCTTTAGATGATACCAATCCAAAATTTCACAGCGAGAAAACTGGTCTTGACCAAATTCTCGCACTAGATTCCACACACCATCGTGACCATCTCCCAAGCAAACAAGGGGGTCTACCAACTGTTGGCTATTAACATAATCAATTAATGATTGGTTGTCATCAAAAAATGCACCATAGTAAATCCCTTGCAGGCGAACAGTTTTATAATCTCGCCAGTGACAACCTGCTTTTGGTTTACCTCGCAGTCGAACTTTGCCTCCATCTACACTTACTTCGGAGACGGCTTGCAATGCTAAGGGTAGTTGAAAATCTTGTGACAAAACTAATTTTTGTTGGGTTGAGTGACCAACTTTTACTCCTGTTAGTGCCTCTACCTCTATTTCTGCATTCTGGTAGGAAATATTTGCTGATAGTCTCAAACAACACTTTTTCAGTAATGGACTTAACCTAGTTCTTGGTTTTAAACCCAGTCTCTGTAACTGTTTAGCTTTAAGAGTTAGTTCTCCAACCAGGCTTTTTATTTTCCTTGTTTTACCTACTTTTGTCCCTGTTTTCTGTTCGACAAAAAAAGGGCTATTTCTGGACTCACACGTTCTAGTATTTGACTACGAACTTTTTTTTCTATACTTTCTAGGTCTGTTAACTGACTCTTATCCGCTTCTTCATATAGTAATTTTGCAAGTTCCCTTACACAGGCTTTTATTTGTTCTTCTCTATCTTGGCTCATAGTAGTTGATGCACTCTTTTTATCTCCTTTTACATTCTCCCTTATTTTGTATATCTTCCAAAAGTAGATGCTCCCGAAATATTGTTGTCTGGATGGTAATCTACCAATAAATGAACATGGTCTTGTTCACCTGAAAATTCTACCAATATGCAATTAGTTTTAATGCAGATATTTGCAAAAATATCGTGCATCCTCTCAACGATTGGTGCGGTAATTGCTTTTTTGCGATACTTAGTAATGAAAACAAAGTGCAAGTGAATAGAAAAAAAACAGCGTGTGACCCTTTACGAGGAAGCATTTGATAAGTAACCGTGTCTGTTATATTCTGATTAATATACCAGATTTTTGGAGGAAACAAAAACATCCTGTGGCAACAAGACGAATGACCTTTCGGCTATACCCAAACAAGAAAACTGAATTAATTTTGCGGTATCACCGAAAGCTCCATAAGGACTTGTATAACGCCGCAGTAAATAACAGATTTAACCAGTACAAAATCTATAATCACAAAGTTGATTATTTTGAGCAGCAAAACTGTTTACCTGCGTTTAAAGAGATTTGGATAGAGTATAAAGAGCTTCCTAGCCATGCACTGCAAGCAACTCTTAAGCGTGTTGACTTTGCATTTGAGCGTTGGTTAAAAGGATTAGGTAAGCGTCCGAGATTTAAGTCAATTAGACATTATTCAGGATGGACTTATCCAGACTGTGCAGGTTTTAAAGTAGAATCTGAAGGCGAGAATGGATATCTCAATTTGTCTAAGATTGGGCGTATTCAAATGCGTGGACAGGCTAAATATTGGGGCAAACCAACTACTTGCACTATTCTTTATCGCAATAGTAAATGGTACGCCTCGATTACTGTTAACGTATTAGACCAAATTCTCAAGCCAGAGATTCTATCCTGTGGTGCTGTTGGTATTGATCTGGGGTGTAAATCTGCGCTATCAATTACTGATGGGGAAAATCATCAACAAATTGACGCACCGAAATTCTTGAGAAGCGCAGAGCATTTAATCAAGAAAGCTTCTATTGACAAGAGGCGTAAGCGTGCGCCAAATAGAAAGAAAAAAATAAAAGCTTCTAGACGGTTCAAAAAAGCTCAATTAAAAGTTAGTAAGCTTACCCGCAAGGTTGCAAATCAACGTCAGAATTGGGTACATCGGGTTGCAACAGAAATAGTTAGCAGTAATAGCTTCGTTGCAACTGAAAAGCTAGAAGTCAAAAACATGACCGCTAAAGCTAAAAAAGGTAAGCGCAAGAAGCAAAAAGCTGGACTAAACAAGTCTATTCTTGACGTTGGTTTTGGAATGCTACGCAGCACCATTAAATACAAAGTTGAGCAGATTGGTGGTGTATTTATCGAAGTTCCAACGCGAAGAGTTTTGCCTTCTCAAACCTGTCCCAAATGCGGAAATCAACACAAAAAAACACTTTCGCTCCGAGTGCATGAGTGTAGTTGCGGATACGTGCAGGATAGGGATATTGCTGCTGCCGAAGTTATGCTTTATTGGGCTAAAGGCAATCTGCCGGGGTCAGGAACTGGCCTCGCAGACGCTGATGTTACTAGCTCTACTTCACGCACCCGCAAACAAGCGGGAAGTATGAAGCAACTGGGGCAAATGAAGCGTCAGAAATCTCAGGTAAAGCTTGCTAAAAACGACTTTGGGAATGTAGAAACCCCAAGCTCAGGCGAAGCCAGCTTGGGGTAGTTCATAATAAAAACAATTATCAGATTCAATTCCAGCCTTTTTTAGTTCTCGCTTCCAGGTAGTTGAGCCGTAACACTCATAATCTAGCTCCAAAACATCAGCCGTATCTTTGATTTCTTTAAGCCGCACACTCGTGACTTCCAGTCATGAGTTAGGCGTTCTATATTGAGCGTAACTTCGTGTTAAAATTAAAGTGTGCAGTAACAATTGTAAAAAAGTGCCAGCCATCCAAAAAGCATTTAAAGTCACTCTCATACCTACACACAACCAAGAAGTCTTAATCAACAAGACTATTGGTTGTGCAAGGTATGTGTACAACCGCTTTTTGGCATTAAGAAAAGAGCTATATAATACTGAGCAAAAAACCTTAAGCTACAACGCTTGTAGTCAGCAACTAACTGTACTAAAGAAAGAAAATGAATGGCTCAAAGAAGTAGATAAGTTTGCCTTACAGAACTCACTCAAGAATTTAGAGACAGCATACAAAAACTTTTTTGCTGACTTAAAGAAGGTTAAAAGCAAGAAAGTGGTAGGGGTTCCTAAATTTAAAAAGAAGCATGGGTGTAAGCAATCTTACAAAACTAACCTGACTAACGGCAACATTCAAATTATAGAGAATCGTTTAAAACTTCCCAAGTTAGGATGGATTAAGTTTCACCAGTCTCAGGACATTAACGGGAAGCTTGTAAACGTTACCATAACTCGTACTTCATCAGGTAAATATATTGCTAGTATTCTGTGTGAAACAGAGATAGAGAAACACTTTCAAGTTACTCAAAATATTGGCTTAGACTTGGGAATTAAATCCTATCTTGTTACAAGCAATGGTGAAGTTGTAGATAATCCCAAATATTACCGGACTCAAAAAAGGAAGTTACGTAAAGCACACAAAAAACTATCTCGCACTGTAAAAGGTAGTAGTAATAGAGCCAAAGCGAAAATCAAGCTGGCTCGTACCTATGAACGAATTACGAACTTGAGAGATGACTTTCTGCACAAGTTGTCAACTCGTCTAATCAAAGAAAACAGCATTATCTGTATTGAGGATTTGCGAGTTGCCAATATGGTAAAGAATCACAAACTAGCATTGAGCCTGGCTGATGCTAGTTGGACTAAGTTCGTTACTATGCTTGAATATAAAGCTTTGTGGCATGACAGAATTGTGCAAAAAGTCGGGACATTTTATCCTTCGTCTCAAACTTGTAATCATTGTGGTTTTATTAACCCATTAGTTAAAGATTTAAAGTTACGTGAATGGTCTTGTCCTAGCTGCAATAGTTACAATTTAAGGGATAAAAACGCAGCACTTAATATATTAAGTGAGGGTTTGAGATTACTAACCGCCGTCGGTACGCCGGAGGTTATAAAAAACGCCTGTGGAGAACTTGTAAGTCCTGAAGTAATTCAGGCACAGATCGTTGAAGCAGGAATCAAGCCACTTTTAGTGGTGTGAGGTTCAAGATGTCACCAATTATTTCTTTGTAATATTCGTGTTCTGGTAACGGTGTCATAATCTCTAATGTGCCATCATCATAAGCTACCCTAGCTGAACGGCTTTCACCTAAGTCTACTAATAAATTCTCAAACTTTTGCCAACTGATATTATAAAGAACCACTCGGTCAGCGCGATGTTCAGTTAGCAGCATAATTCCTCGCAGAATCAGTAAGCAGTTAATGATAATCAGTATTCAGTAAGAACTTAGTATAAGTTTCCAAATTTATAACTGATTACTAACTAATATCAAAATCATCCTAATTCATTTTATCAATTATGATTAGTGAATATTTCCAAACTCTAACCACCTTCCCCCCACGCAACTTTCAACGAGAAGCGATCGCTAAACTCTTACAGCGTCAAGACATCCTCCTCCGGGCACCAACAGGGTCAGGAAAAACAGAAACAGCGATCGCACCCTTCCTCTTCGCCAAAGCCCTGAATATAGACTTTCCCAATAAACTCATCTACGTTGTACCTCTGCGAACCCTAGCCAACAGCCTCCGCCAACGGGCTGAAATATTAATTGCGAACTGGGAGAAGGTTTATCCATCATCCCATTTTCTAGCTGTCACCCTACAAACAGGAGAGAACCCAGAAGACCCGCGCTTTGAAGGTGATATAGTTTTCTGCACAATTGACCAAATGTTGAGCAGCTTCCTGAATATCCCTTACTCAGTCGGTCGTGGTTCTGCCAATGTGAACTCAGGAGCAATTTTTGCTTCATATCTAGTATTTGATGAATTACATCTGCTTGACCCAGACCGCTCTTTCGCTACTGTTTTGAAAGTTTTGCAACAAGTTAAAGGCATTTCCCCATTTTTGCTGATGACCGCCACTTTAACTAATGAACTTGCAACCCAAATACAGACGTTGGTAAACAATGGAAATTATTCAAGTTGAAGATGCAGATTTACAAGCGATAGAAGGCGATCGCTGTCGTACCTTTCAAGCTGTGTCCCATCCTCTTAACGCTTCGGTAATCCTAGACGATATTCGAGCTTATCAGCGTAAACGAGTGATAATCATCTGTAACACAGTTTCTCAAGCTCAGGGATTATTCCGCGATTTAGAGGAACTGAACTACGAGGGAATATTACACGTTACATTGTTACATTCTAGATTCCTCCCAGAACACCGCGCCCAAAAAGAAACTGACCTCAAAAGCATATTTGCCCAAAGCTGGCAAGATGATGGTAATTGCTACGTTTTGATTTCTACCCAAGTAATAGAAGCAGGAATCAACATCACCTGCCAAGTCATGCACACTCAACTTTGTCCAATGAACTCGCTTTTACAACGGGCTGGACGTTGCGCTCGGTTTGGTGGTGAGCAAGGAGAAGTCTATATTTATCCTACAGTTGAAGTTAACGCAGCTTCTTGTAAAATAGCGATCGCAGATTTAGAACTAGAAGAAGAATCAGCACCTAAAAAGCAAAGCTTTCTGCCATATCCTCAAGAAACCTGTGAACTCACATGGTCTGTGTTGCAGGAACATACCCAATCTGTACAAGCGAATGAGAATGTTGGATTTCGTACTGAAGAACAATGGATAAATCAAGTTCACACTAGAGAAGACTTACTACAGCAACAGCGACGACTTAACAACCGGATGAATTTTGAACAACGCTTTGAAGATGCGTTTTTTAGAGGGGATCAATCTGCCGGGAGAGAATTGATTCGGTCAATCGATAGCCGCAGTGTATTTATCTGGGAAGAAGATGGCTTAATTGATATTGAAGAGGAAGTAGTTGATCCCCAAAAACTGCTAAGTTTTTCGCTGCCTGTTTCCATGCTATGCAAAGTGTGGCGGGAGTTTCAAAATATGGAATTTGGAGCAGACTGGATTTTTAAGCAGATTGAAAATCCAAAAGGGAAAGCAGAAACGTATAGTCAACCTGTTTGCACTCCAATTAAATCTCGTGAGGCACTGATTGGCAGTATACGGATTTTAGTCAATCCTCGCTATGTTCATTATGACGAACATATTGGCTTGTTAATTGGTATTGATGTTTTCGGGAACCACTTTGTTTCTCCTGATAAATCAAAACGTGTAATCGCCAGTGAGTATCGCTATAACATGGACAATTATGTAGGGCATCTAGTGTTGATGTGGAAATGCTGGCGGGAAGTATTTACAGTAAACCGATTAAAAAATGGAGTGTCCCAAGAAACTACTTTTACTAGTGTTCGTGATGAACTGTTAGCGGCTGGTGGACGATTTATCAGAGGTAAAATTTTTCCGCAGACGCAGGAGAAAGAAGCAGAAGCTTTATTTGAAATGTTGGTATTTCTAGCTATTTTCACCCATGACCTGGGGAAACTGCAAGTGAAATGGCAAGAAGTGATGCAGGGATGGCAAGCGATCGCTCATTCTTCATTCTCTGGCAGAAACCCTGGAAAACATCTATTAGCGCACACTGACTACAGCCCAGAAGACAGACATCAACGAGATGCGCTCAAAGACTATGAAAAGAAACACAAGCGTCCAAACCATGCTGTTGAAAGTGCTTACTTAGCCCAAGATATTCTTAAGCAATCGTTAGTACCCCTACTGCAAGATAATTTCTTGGCAGACATAGAGCAAATTAAATACATCTGTCATACAGTAATCATGGCTGCGGGTCGTCACCATTCTGCTTGGGCAGGGGGATGGGATCAAGCAGCAACAGCTAAGATTAAAAGTATAGAGTTACACCCAGGGGCAAAGCAAGCGATCGCTGATAGTTGGCGGAGTATTCATAGGTTTCTGCCACAGCCATTATCCTTAGCAAAAGCAAACTTGGGTAAAGATGTGTACCCGATTAAAAAAGACTTTGATTTAAATAGGTTTACCCCCGACCAAACTGAATATTTGCAACTTTACTTGCTAATAGTCAGAGCTTTGCGCCTTTGCGATCAGCGTTCAGTACAGCTTCACAATATCTAGCTATCACCGGAATCGACCAGCGAAGTCTTGATTTATCGCCTGTGCCCGCAGGTGTGCCATCACAAGTACAGCAAAGGAAATATCCTAGCGTGGCAAAACTAGCTAGAGCAAAAATTTAAACGTAGTAAATTCGTTATTATTGAAAATTTTGGTTTACCTATTTACGCCTATTTCAATCATTAAAAATCTACTCTAGCAAGTTTTACCACTCTAGGAAATATCAGTTTGCTCTAACTCTAACCAATAGGCTTCGTATTTGGAAAGGTCTGACAGATTGTATTGGAATAGCCCTCTTCCAAGGGGGTATAGAATCTTTGGAAGTACACAACGCTCATGGGTAAAACGCCAGATGACAGAGCGCTTATTTATTACCAAAAAATTTGGCACTTATGCTGACACCTTTCTAATGCTAGGTCTGGTGCAGCTTGTGGAATATGCCCTGAAAGCGACTAACCAAAAAATCGATATTCAGCTTGTGGATGAAGGGACACGCTACTGCATCCAGTTGAAGAAGGCTGTCAATTTAGAACCAATAGGTAAATTAAGTTACACCAACCCCTTTCCACCAGTCAAAGGTAAAAAGACAGATATCAGCAAAATATCTCAGGAAACAATTATCTTTGACACAGTAGAACAAAGCGATGCGCGAAAACTCTACCGAGATTATGTATTTCAGCAACGGGGCAAAGTTCAATTTCATGAAGATGCACCAGATCCACCCCATCCTAGTACTCAAAATGGTGTAGTCCTAACTTCGATGCGCCACGATCGCAATCATAACGAACTGTGGCAATTGGGTTGGCAGAATAAGGATGACTACGGCATTTTGCTTGTTACCCTCTTCCAAGCTTTTAGCCAGGAGAATTACTCTAGCTTGAATGGAGAAACTAAGCAGGTTGCGGAGTTATTCAAACAAGCGACTGGTCGCCAGTTGCCTAGTGAGGCCAGTGCCGTGAAAGTTTATCTGCCCACATCAGTTCAGGGAGTTAACCGTATCAAGGCAGATAGCAACAAAGTAGATTCTCAAAAGGCAGATTGGTTAACTTTATGGCTGATTGCAGGAGGATTATTTAGCTTTGGGGTTGCGGAACGGGTCAAGATTGCCGAACGAGTTTATGACTGGCGAGTTGTAGCGTTGGAACCATTAGATATTCAGTTGAGCAAATATCGGGAGGTGTTAGATAAATTACGCAAATATAACCCACCTTCTGGAGGATATGGGATTGCCCGCTTTGATGCAGAGTTGGTGTTGCGGTTTTGTCAACAATTGCTCAATAGTCACCCATCTCAAGCTGATGCAGAACTAGATGACTTTGACCTATGGCAACCGATTAACCATTTTGTCAGCAACTTTGTAGGTACTCACTTTGGCTCCAAAGGGCAAGTTTATGGTGTCAAGGAAGTTTTTACTTTGGGGCTTCCTGGGTGGATTCGACCAGAAAATTCTGAGGAATTGACAGATTATCTGAAGGTTCTAAATGAGCATCTGTTTGTGATCGGTAGCCTATCGGCGGAAGAGGGACACAGCGAACTGTTGGCTGCATATCGAGATTTTATTACTGGGACAAATCTTCGTAGGTTTTTTCGTTTTCAGGCCAGCTACGCCGATTACATAGTTAAACGCTTGGCAGATCCCAAAGCAAAACCTCCCCGTTTATTTTCAATTGCTGGACTGAACACTATGACTAAAAAAGACACAGATTTCACCAAAATTACTACAGACCCCAGCTTTCTCCGCATCGCCAAAGCAATTAATCAAGCAACAGTATATGCAGGGAAGGTGAAAACCCAACAGGGTGTTATAGAACTAGATTGGCAACGCACCTATGGATTGGCACAGCGTTTGAGCAGTCAATCTGGCTCCAAGAAGGATTTTTTGAGCGAAATTACTGATTTTCTGGCGAAATACCAAGCAGAAAATTTACGCTTATCGGAACAACTTCTCAAGGAAGGCAAATCCCTAAGACGAGTTTGGACAACCAAAGAAGACTTAGATCGATTAGTTGAATTGGTTGAAAACTATGACACAGTACTGGTTGCCAATTTGTTAATTGCCTACGGGTATGCCCGTTGGACAAAGGCGAAGGAAGTGGATTTGGAAGATGAGAATGCGGATATTAATGACGAGCAAGATTTAAACAACTTGGAACCAACTGAAAATTTAGGAGAATCCAACAATGACTAATACACATTTTCCCGTTCATTCAATTTCAGTTAGTGGTACATTGTCCTGGCAACTTCATGCTCTGAATAATGAAGGCAACGAGGGCAATCAATCGCTAACGCGACGCTACTACATTATTCAGAAAGACATGACTGAACCTGAATATGTTAATGGAGTTTCCGGGGATATGCTCAAACATATCCAAGCAGAACATCTGCACCGGATTGCGATTCAGGAAGGGCTAACACTTTCAGAAGGGGGCAAGCAATTTCATCCTGACCGTATTGGTTATGACTTAGAAAAAGGACTTCCGGTTTTTACGCAGTCAAACACAGATTTAACTGCCAAAACGAACCAAGTACTCCAGCTTTGCACAATCAGCGACTTAGAGGGATTTATGGTGACAGTTAAGGGTGGACAAACTCTAAAACGGGAATCTGTAATTGAGTTTGGAGCAGCTGTAGGTTTACCAACCTTAGTCAAAACCCAGAGCTACTTCCATGCGAAATATGGGACAGATAACCCAACTCCTTACAATGTACAGGTAAATTCCGGTTTATATGCAACTGTCCTCAATATTGAAGCTTTTCGTATTGGCTACAATCCCCACAATTTTAGCTACAGCATTGATCCTATTGAGCGCAAAAAGCGGCTAGATGTCTTACTAAAAAGTGTGCTGTATACATACCTGCAACCCAATGGTGCAAAGCGCAATACCCATTTACCCCATCCTGACCATTTTGAAGGTGTAATTACTGTTAGCACTCGCCGTTGTCCCGCACCAATGCTCAGTCCCTTATCCGCAAGTTACAGCCGCCAAATTCATAGCTTGGCTGACACCCTAAATAATCTCAACGGTGCAGGTACAATTCACTGCTTTGATTTTGAGACAATTGCCCAGTTCGCCGAACAAATTCAAACCCTAATTGAGCGATCGCAACCTTGGGAGAGTAACAATGCCGAAGCCATCGAATAAATCAAAATCTTCACTGTCCAAACAGGAGCAGCAGGTGAAAGTAAACTCCAACCAATGGTTAACCCTTACTTATCAGCCCGTTAGTCTATTCTCCCTCAAACGCTCCGATGCAACGAGCATGGCGGCTCGGTCGAATCTAGTGCCAACTCCCTATGCGATCAAGATGGCATTGCTGAAAGTCTTGCTCGAAAGTCAAGGAAGGCAGCATCAAAGTAATTTTGATCAATGGATTAAAAGCGAATTTACCTGGATTCGAGACTTACAAATTTATATTTGGCCACCAGAGCAATTGGTTGTGAATCGCAACGGCTACAAACTCCGCTACTACGATCAAACTGCTGATAAGGCAGATAAGAGCCGGACAACACTACCTATGCAGGGTGGGTTTGTTTTTCGGGAATGGGTGCATTTACAAGGACATCTACAAATTTGTTGTGGTGGTTGCGATCGCTTGGCAGAACTAGAGCGGCTGTTTGCTCAAATTAACTACTTTGGCAAACGGGGCTGTTTTTTTCAATATCTTCCAGAATACAAACAAGAAACTTCTGAACCATTATTTCAACCAAATCTGATTACTGGCTTTACAGCACAGCTAATGGATGATTTAGGTGAAAAGGCTACGTTTAACCGAATCAATCCTTTTTCCACTGAGAAGGCACAACTGGACAAAGACCGAGTAATTAAGCCTGGATTTCTACCTTTACGACTTGTTGCTACAAGCGCCCGTTATGATATGTACCAAAGATACTGAAGTCACATTCGCTGGACTTAGCATAGTTCTTAAACAAGTAGAAACTTCAATCAGCCCCACTCCACTGAACTCTTGGCTATCAGAAACCCAGCTTTTACCAGTTTGGATTCCTTTACGGATTAACGGAGGTGTTACCAAAATTATGCCTGTATTGCCAAGCTCAGTTCTGTATTCAAATCTGATGCAATCTATTTGTCAGCAGATTGCTCAGAATACCTTGGTGGAGTGGTGGCAAAAACCTTATGAACTAACAGGGGTTGAAGTAGATTCTGATGCTTTGCATGTGATTCAAGTTTCTGTTACATCTGCCGCATCCCTGCCAGCACTGGGACGAGCCATCCATGCTCAATGTTTTCAGTGGTTTGCTAATGCCGATACTGCCTTAGCTGAACACTTGCATCAACAAAATACCTTACCGTTAACTGCGGCAATGCAGTATGTTTCTCCACAAAAAATGCAGTTGAGAATTACCTTGTTGAAAAAAGAACTGCTAGCACCTTTACTTTGGGGATTAAGTACCAACCTGGGAGAGTCAATCATGCTGGCAGGCATACCTTGCCAATTGGGGAAGTGGATAGATATCGTGCAAGTTAGTAGTTTTGAAAAACTACTACAGGTAACAACCCAAAGTGTGATAGAGTTGCGCTTTCTTTCACCTACTAGCTTCAAGCAAAATCGAGGAGTACAGTCTTTCCCCCTACCAGAATTGGTTTTCAACAGTTTATTGCGCCGTTGGAACATATTTGCTCCACCAGAACAGCAATTTCCCGAGGTGGAGTGGAATGGTTTAGTTTCTGCTTATGATCTCAAAACCCATGCCTTAAAAATGGAAGGTGGAGCAGAAATTGGTGCCCAAGGATGGGTAAAGTATCGATTTTTAGATTCCCAGCAAGCAAGAATAGCCACAATCTTAGCTCATTTTGCAACATTCGCGGGAGTTGGGCGCAAAACAGCGATGGGAATGGGGCAAGTGAGATTGGTTGAATCCCGCTTACGAGGCTGAACTAAAAATACGTATTCAAACGAAAAGATGAATGAAGATTACTTACCTTTGGCATACCTAAATGCCTGGGAATATTGTCCACGCAGATTTTACCTTGAATATGTCTTGGGCGAAATGTCAGATAACGAGCATATTATCTTGGGTCGCCACATACACCGCAATATCAATGAAGAAGGAACACTTCAAGAAGGAGAGATGCTGATTCATCAGCAGCAGTGGGTCTGGAGCGATCGCTTGAAGGTCGCAGGTATCATTGATGCAGTTGAAGAATGCGATGGTCAGCTTGTCCCTGTGGAATATAAAAAAGGGAAGATGGCACAACATCTTAATGACCATTTTCAACTTTGTGCAGCAGCTTTGTGTCTAGAAGAACGTACCGGACGCTGCCTTGCTTATGGTGAGATTTTTTATCATACTAACCGCAGAAGACAGACAGTAGCATTTACACCTCAATTACGACAAATGACTGAGCAAGCAATTGTTCTTGCTCAACTTGCATCTCAAACAACTATGCCTGTACCAATTGATAACACTAAAAAGTGTCTTTCATGCAGTTTAAAAGAGATTTGTCTACCTTTTGAAGTTAAACAGTTACGGGTGTCAATGACTTCTGAAACCGAGGATTAATTTCATCGGGAGTAACTGACCCCTAAATTCAGAATAGCTGAATTCTTCTTCAACCATAACTCACTATCACAAATCTAAAATGTCAGTACTTTACGTAACTCAGGCTGATGCCGTTTTGAGCAAGAATTACGAAGCTTTTAATGTTGCTCTTAAACAATCAGATGGTTCTTGGAAAAAACAGACTGTTGCAGCCCAAACTGTTGAACAAGTTGTCTTGATGGGCAATCCTCAAGTCACAGGTGATGCTCTAGTTTATGCTTTGGAATTAGGTATGCCTGTTCACTATCTTTCTAGCTTTGGTAAATATCTGGGTTCTGCACTTCCTGGTTATTCGCGCAATGGTCAATTGCGATTAGCACAATATAAACTATATAGTGATCCCGTCGGACGTTTAGAATTAGTTAAAGCAATTGTGACAGCCAAAATTCATAATCAATATCAGGTTTTGTATCGTCATAATGAGCGAGATAATCCTCTTAAAGAGCGTAAAAGTCTTGTTAAAAGCCAAAAAACCATAGATCAGGTTAGAGGGATTGAAGGTTTAGCTGCACGAGAGTATTTTGCTTGCTGGCCACGGATGGTTGGAAAACAATGGACATTTACTGGTCGAAATCGTCGTCCGCCTACTGACCCAGTAAACTCGTTGCTCAGTTTTGCCTATGGTTTGTTGCGAGTTCAAGTAACGGCTGCGGTTCATGTTGCTGGGTTAGATCCTTATATTGGTTATTTACACGAAGTCCATCATGGTCAGCCTGCAATGGTGCTGGATCTCATGGAAGAGTTTCGTTCATTGATCGCTGACAATGTAGTGTTAGCTGTATTGCATAAACATGAAATTCAACCTGATGATTTTAACGAAAGTTTAGGTGCATATCGCCTGAAGGATAGTGCCAGGAAAACTTTTTTGCAGGCATTCGAGCGCAAAATGAATGATGAATTTAAACATCCTGTTTTTGAGTACAGATGCACTTATAGACGAGCGATTGAACTACAAGCTCGGCTATTGGGTCGCCATTTACAAGAAGGGATTCCATATAAAGCTTTCGCTTTACGTTAATTATCATTCATTTATTGAAAAATTTGACAATGACTACTCTGTTCTATTTGATTATTTACGACCTGCCTGATAACAAAGCTGCAAATAAACGTCGCACTCGCTTACATAAAATGTTGTCTGGTTACGGGAAATGGACACAATATAGCGTTTTTGAGTGTTTTTTAACAGCGATACAATTTGCAACACTCCAGACCAAGATAGAAAAACTGGTTAAGCCTGAAGAGGATTCGGTACGATTGTATATACTTGATGCGGGTGCAATCAAACGAACAATTACATACGGATCTGAAATCCCTCGACAAGAGCAAACAATAGTTTTATGATTATGTAATCAGCTTGATGGATGGCAAGCCGAAGCGAGGGCTAAAACCCTGGGCATCTGCCAAAATCGCCAGAACCTTGACAAGTAAATAATTACAGCGTTTCAAAAATTCGGGAAGTTGCAAATTACTCGCAATAAGAGCGGCTGAAAATGACCTTTTTTTTCGATCCGTCAAAAACCTTCCCAGGAAGCTTGCTCCGTAACAGTTTCAGATGGAGCGGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACATATTCTGAAATTCGACGGCCATCCGTCGAAGCTATAAGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACTAATAGCATTGTTATGAATATAGAGAAAAAGAAAGTGGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACATTAAAGAGTTGGCTAGCGATCGCAGAATATGAACGGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACCAATAGTTGGATCTGAAAGCATCTCAACTATTTGGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACTTGCCAGTTTCATGGTCTTCTATAAGCACTATGGCGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACATTAAACGTGAAACCTGGATTACTTGGGAGAAATTAGGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACTAAAGCTGCTCAAGTCCTTGGGTTCTGCCAAATAGCTCTAGGGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACAATAATTGGGCAACTGCGATCGCAATTACAAAACCACACAGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACTAATCAGCACACAAAGCACAGTTTAGCTTTATTCCTGCGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACAAGAGATTGCCTTTTTCCTCAACCCTGATTAATTCAAGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACATATACTTTTATTTTTGATGCACTCATAAAAGAAGGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACCTACATTTTTTAAAGTTAGACTCCAATAGTTAGTATGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACATTTTTTTCACACCGACTGAAGCAGCAATTTTAAAGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACCTCCCTAAAGCAATCTTACCTTTGTTAGCTGTCTTTTGCCAGGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACTTGTATGAGTAACAACACCTATCAAATTAATCTTGTGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACATACTCACGCAGGCTTGATAACTGGTATCAAGGCAATGGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACCTCACGATGAGAAAGTGGAGAAGCAAGCCCGTGCTATGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACTTACATTCATGCTTGTAAACTTGTAAAAGAATTAAGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACGTTCAGAAATTTTATCCTTAATGTTTTTGTTTGGGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACAAGAAGAAACTCATTCCATTAACAAAGTTAGTCCGGCGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACTATGAGATGGAAACATCTTGTCCTTTAGCTAATTCCTGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACCAGAACGATAAGTATAAGGCTGGTGGTCATATAGTACCGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACAGAGTTTTTATCAGCATCAAGCAGCATCCCAAATGGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACATTCCTTTATGAGTGATTAGCGATCGCTGAGAACTTCAGAGGTTTCCAAAGACTATTACCCCGCAAGGGGACTGAAACAATTAAAGTTCTCAGCTTTAGCTTGGGCAATAAGGTTTCCAAAGACTATTACCCCAGAAGGGGACTGAAACTTCAAACATTAATTGCGATCGCAGTTGTTCAAATTAGTTTTCGACAATTAACTCATCGCCAGGGGAATTAATTGTTGTTTGCCTTTTATTAAGTCAAAGAGGATTGAAATTGCGTACAATATTGAGCATTATTTGTGAAGCCCTAAGCAATGCCAAGAGCAGCATCATCTACTAGTGGTAAACCAAAGCCAAAGCAAAAATCTGTTGCTTCTGTTGTCACATGGGCAGATGAGACAGAATTAGTGGGATTAGTGTTTGAACTGGAGTCAACTGCTTCTGCTTTGCTTTATTCGCAGTACACAATAGGACTGCACGCGTGGTTTTTGGAGCAAGTACGGCAATTTGATCCAGACCTTTCAGCTTATCTTCATGATGGAGAGTCAGAAAAACCCTTCAATATTTCAGCGCTGTCAGGTCAACTAATTGCCAGTGGCAAACAACTACGATTAGAAGGGAATCAAATATACTACTGGTACGTGAACGTTTTATCTCAACGGGTAGCAAAGTTTCTCAAACACTGGTTAACTCAACTACCAGAACGCTTAGATTTAAAAGGTGCATCTCTACAGATAAAACAGGTGAGCATAGCCTATGCACCAACTACCTACAAACAACTACTGGAATCATCTACAGATAGACCATCCTCCATCAGTCTCAGTTTTATTTCACCTACAAGCTTTCGTCGAAAAGGAAATCATTTCCCTTTACCAGTGCCAGAAAACCTTTTTCATAGTTACTTGCGGCGGTGGAATGATTTTTCATCGATGCCAGCAGAACAAGAATCATTTCTCAAATGGATAGATGAAGGGGTGATTATTCATCAACACCGCTTGAAATCAGAGAAAGTGGCAGCAGGGAAGCGTGGGTCAGTCACAGGTTTCACAGGTGCAATCTCATTAGGTTTAACGAAAGCAGCTTCAGCAAACTTTGAATTTAGTGAGTTGTTTTATGCTTTAGTACGGTTGGCTCCTTACTGTGGCACAGGGCATAAAACCACTTTTGGGCTAGGACAAACTCGTTTGGATTGGGTAGAGCAGGAAACGAGTAAATCAATTCAGTTGATAACAAATCTGCTGGGAGAGCGAATTGAGGAACTGATCAAATTATTTACTGCACAACGCAAACGTACAGGAGGGGAGCGAACTGATAAAATTGCAGTTACCTGGGCAACGATTTTGGCGCGGCGGGAGATGGGGGAATCATTGAAGGCAATCGCCGAAGATTTAGAGATGCCGATCTCGACCGTGAAAACTTACGTGAAATTAGCCAGGAAATCGCTCAAACAAGAAAGTAATAGCTGAAAAAAAAGTTAAAGGTTAAGAGTTATTTGCATTCACTCATTACCAGGAAATCGCTCAAACAAGAAAGTAATAGCTGAAAACCTTCGCTTATGGACAAGGGTAAGTAATTATCTTATGATTAGGTAATCAGCTTGATGTTTTGGCAAGTCGAAGCGAGGTCAAAAACCCTGGGGATCTGCCAAAATCGCCAGAACCTTGACAAATAAATAGTTTCACAGTTTCAGTGCTAAGGAAAGTTGATAATTAGTTGCAATAAGAGCGGCTGAAATCGACCTATTTTTGAGGTTTGCCAAAATGCTTCCCAGGAAGCCTGCTCTGTAAGGGTTTCAGCAACGAGCAGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACGTTCAAATGCTGTCTCTTATCAAAATCAAGTTCGAGGAGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACTAATAGCATTGTTATGAATATAGAGAAAAAGAAAGGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACATATCTGAATTTTTCGAGACTGGGAATATTCATAACTGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACAATTAACTGGTTGCGCCTGCTCAACAACAATCGAGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACACCACCGGAGGCAGAAGGAAATCTGGTGATCGTATCGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACTAACTGCTCTGCCACTTCCCGATAGTCATCTGCGATGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACCCCAAGAGAATATTGACGCTTTAGTTCATCTAGAAAGGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACATCACACGCTTGGTGATAACGCAATACTAGGACTACAGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACTCATCTTGAAAGCCACTTACCAAAGAATTGGATTAAGGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACCTGTACTTCTCTAAAAAGATGGAAATTCCAGGTGGGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACGCTAGAGGCGATCGCTATCTATACTCGCCTCCAACGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACGGGTTATTAAGCTTTACACTACCCTTTCTAAAGCCATGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACATTTTTATCGCTCAGATGCACCATACAAAAACTTACTGTTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACTTCAATCCACGCTTTCATTATTCCAACAATTTATGCGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACCTACTTCGGTTGTCATAGTGTGTTAGTCGTTTTTGGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACGTTCCGTTACCCATGTCAATTAATGTCCAATCCCTATGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACTTCGTAAGCATACCCTCTGCAATCAGACAAAGGATGGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACCAAATCAATGGTTGTCTGTGCCTGTTAATAACATTAGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACTCAAATTCAATTACTTGATGAAACTCACCCAAGACAGGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACGCAGCAGTAGCTCGCTTGGATCATCCGGCAGTTTGGTTTCCACCAACCAAATCCCCTCACGGGGACTGAAACATCATTTAGTTTGATTCTAAACTTTCCAATTGGGCTGCGTTTCCATTGACCAAATCCCCTCACGGGGACTGAAACGAAAAAGCGGCAATGCGATCGTTTTCGTTAGAAAAATGTTTCCATTGACCAAATCCCCTCACGAGGACTGAAACATTCGGATATTTCCTCACTAAGCGATCGCCTATAGGCAGTCTCCATTGACCAAATCCCCAGCCGCGATCGCTATGTTCAAAATTTCTTCAAAAGTGAGAGAATTCGAGAATTACGCTATTTTCGGCTATTGGCTAAGTCTTCATTGTGGGATGGGTATCATGTTCCGTAAAGGCGTTTGATCAAGCGAACGCTTAACCCTGTTATGTCACTCTCGGAAAACAATAATTGAAGCAAGATTCTGAAACTTTTATTGAGTCAAGCTTTGAGACATTATTTTCTAACAGAAACTAAAATTTCTAGCCAAAAACTGAAAAGTAAAGCTCTCAAAGGCTTTCAGGCATTGGCTTCTCCCAAAGTGACAGAACAGGGTTAAAACACCCAAGGTTTTTCCTCAAATAAACACTGGTATTCTTTTAGAAATTATGGCTACGGTTATTACTGAGTTACTTCAGTGCTGATGAGCTATTAAAAAATTTAAATTATACAAATTAACATCCGGAAAACAAAGATGAAGTTAGGAAAAATAGTGAAGATATGATTGTAACTTTCTTTGATTGAGTTTATATAAAAGGCTTTTACAATGGTTACTACTCCTGTATATTATTTGCAATTTCTGGACAATCCGAATATTGAAATTTCTCAAGATGAGTTGCGATCGCTTTTAGGAGAAATAGAAGTACAACTGCATCGTAGCAGAGTTTATCGACGTGCTTTAGCGATTGTGCAGAAGTTAATAGGTGAACAAACAGATCAAGCTCAAGATTTATTAAAAGCCGTAGGTAGAGAAGCAATCGGGTTAGCATTTCAACGATTTGCCCAACAATCTCAAAAAGTTGAAACAGTTACAGATAACAAGCAAGCCACAGAAACAGTGAATTCTTCACCAGAGATACAACAGGAGCATTGCGCTCTCCGAGAGGAACCCTCTAAAAATACAGCAGAAAATTCGCTGTGGAAAAAAACACTACAATTGCTGAATCATCAGAGAATTTCTCAAGCAGAACTTGCTGAACAAGCTGAACTTGCAGCTCAACAACGCATGGTGTGCCTACGTCAAATCGGGCAACAACTCCAAAAAACCCGTCAATCCAAAGGGCTTTCTTTGGATCACATCCAGCTTTCCACTCATATCCGAACGGAGCTGATAGAGGCATTAGAAAACGGCAACTGGAAAGAATTATCAGATGACATTTTTGTACGTGGATTTATACGACGTTATGGAGATGCTTTAGGACTTAATGGTGTTGCTTTAGCTGCCTCTTTGCCATTCCTAGCAGCTATACCAGTAACTCAGCCCTTTTCGGATCAATCTAAAAAAGGAGGGGGATTGGAAATTCGCCCGACGCATTTATATATAGGTTATACAGCTCTTCTTGCTGGTGCAATGGGAGGATTAACTTTGATGTCCCAGCAACAAGCAAATACCAATATATCAATTGAGCAAGATAACTCTTCTTCTGCTTTTCAATCGTTAAAACAACAATCCCCTACTGTTAAACCAGGGATTAAATATACTAACACTGGTGTGGCTGTTGGATCTGATATTTTCCCACCAGAAGGGTTATATTAACGAACTGCACGTGCCTGATAACGCAGTTGTGAATCTGGCTTCTACCGTGCAATATAAAACTGCCCTAGACAAAGCTAGAGCAGTTTTTGATAGAAGTAAATTATATAGGAGACTTTTAGTATTGTCCCCGGTTTATCCATAGTAAGTACCGTTATATAATACTATTCACCTCATATTTCGTACTTTACGCAAAAAACGAATAATCTTGAAGTTGGCATTACAAAGGTTAGAAGTCAGCACAAGCCAGCGTATTGCAGATGGCATCCGCTTCTCTACTGTCTACCTCTGATTTTCCTCGATTGGGCTAGGACTTACAGATAGGGAGCGATCGCACCCAGCCCATAGCCCCGCTTGCGAGAGCGATGCTTGCGGCGGGCTATTCGGTGTCGCATTTTCACCTCCGCCAACAAATAATAACAACCAAAACCTGTATATGTACTTAAGATGCTCTTGGGAGCTATTTCTCCTTCTCTTTTGCAGAATTATTGCCAAATTTCACCATGATGAATAACTGGTTTGACACAGCTCGATTGGGGATGTTTATTCATTGGGGACATAGTTCTCAAATGGGATGTGAGTTATCTTGACCGTTAGTTGGGGGTGTATTCAGCCTACCTTTTTGCAAAGATATTCCAGTTGATAAATATCACTACACAGCTAATACTTTCAATCCACAGCAATACAATCCTCAAGAATGGGCAGATTTAGCAAAAAGTCTCGGAATGAAATATGCGATATTAACAACCAAGCATCATAATGGTTTTGCCTTATTCCATACCCAAGAATCAGACTTTTCAATCGCATCTGCACCTTACAAAAAAGATATTGTACGTGAATATGTCGAAGCGATGCGCTCTGTAGGATTGCGTATTGGTCTTTATTTTTCACTTAGTGACTGGCATCATCCTGACTATCCGGCTTGGAGAGAGGCAGATAAACCTTATCGCTTTGACCAACTACCTCAACCGACAGCGCAACAGTGGGAGCGATATATCCAATTTATGTTCAATCAGATACGAGAATTATTGACCAACTATGGTCAAATTGACATCATTTGGTTTGATGGAAGTTGGGAACGCACTCCAGAGCAATGGCAGGCTCAAAAATTAGCAAAAATGATTCGTGATTTACAACCTAATATTCTCATTAACGATCGCCTACCCAATTGTGGAGACTTTGAAACTCCTGAGCAGTTTATTCCTCCTCACCCACCTGCTCATCCTTGGGAAACCTGTCTGACTATTAACGAGAGTTGGGGATACAATTCAGATGATTGCAACTTCAAATCGTCTCGTCAATTGATTCATACAATGTGCGAAATAGCTGGCATTGGAGGCAACCTCTTGCTTAATGTTAGTCCGATGGGTAATGGACAAATCCCTCCTGAGCAGTTAGAGCGTCTCAAAGATATAGCAGATTGGATGGAGAGTCACTGTGAAAGTATACTGGATACAACCCCAGGATTAGAACCGTGGCAATTTTATGGCCCCTCAACTCGTAAGGGTGATCGCATTTATCTACACCTATTAATGAAACCTTACGAAACAATATCAGTTAGGGGTATACCAATCAAACGAGTAAAATCGGTGTTTCTTCTTGCTGACGGTACAGAACTAACTTACACAAGTCGCTGTGCAATTATGGATTCTATCCTCAATTCTAATCCGTTAGGAGAATTAACAATTGATGTACCAGAATCAGTAATTAATCCATACGTTACAGTGATTTGTATTGAGATTGATTCTTGATTAATTAATGTAAATTTAGCTTCTTGAGCGGGGGTATAGCTCATCTCTGATCATGCAGCCCTACCCAAACGGGCGTATATAGCGCTCCCAGTTCTCCTTATTAAATGGACTGCGCCATTTCAAAATTAAGCTCAATTCCAACTGTTGCTGTAATAGTTGAGATAAATTGAGTAGTTTATCTTGTCATTTGGTGTCAGAAACTTATCCGGTATGGACAAATTGCTTCCAGAACAGCTGGTCAAAAGCATTTATCAGGAACTACTGCCTAGATTACAAATTGAAAGTGTTAATCCCCGTAATCCCATTCAGGTCAGCTATCTTCCACAACCTTGGCAGTTGCTTGGCAAAGGAAATTACGCCGCAGTAGTTTTTCACCCCGATTACCCTGAGTGTGTAGTTAAAATTTATGCCCCAGGACGACTAGGCTTTGAAGAGGAAGTAGAAGTCTACCGTCGTCTAGGTTCTCATCCGGCATTTTCTGAGTGTTTGTACGCCAAAGATAACTTTCTAATTTTGAAACGGCTTTATGGAACAACTTTGTACGATTGTATGCACTTAGGTTTACCAATTCCTCAGCAGGTAATACGGGATATCGATAAAGCTTTGGACTATGCTAGAAGTCGCGGACTCCACCCTCATGATGTCCACGGTCGTAATGTGATGATGCATCAGGGTAGAGGGTTAGTTGTAGACATTTCAGATTTTCTGCATCCAGAAGCCTGTTCAAAATGGAATCACTTAAAAAAAGCTTATTATTGGTTATATCGTCCTGTGTTGCGCCCACTTGGATTGCGTGTGCCATACTCGGCCTTAAATATGCTCCGTAAAAGTTACCGTCTGGCAACTTCTTTCAAAATTTCCTGTTGTCAACTAGTCCTTAGATTAACTCGTTTTAAATATTTAAAACTTTAGGCTAATTTAGCCTTGTAACATTAAGTATTTCTGTGCCCAAAAGTGAAAAGGAAATTGTATTGGACCCCTTGCTATTGCTTTAATTTTCAGCTTACTCACTGGTGGCTACTTATCAGCTAATCATACGAAAAAAGTTGAACATTGTTACAATCTCTACATTTACGCGCCCGTAGCTTTTCGCCTTCCCCCCACCCAGCCCCATCAGCACGGAAATACACCCACTGACTTACTGATTCTCCAACGGTACGACCCCAAACAAAATTTTGTGAGCCACAGATAGGACATGGCGTTTCTTGTGGGCTAAGGTTTTCGTGATTGGGTTGGTTGTTCATGAACTTACCCCGATAATTTCTGAGTGCAATCTTCAGCAGCTATTGGGCCAAAGTGCGATGTCTACGACGGTCACTGAGCGCAGCCGTACCACTTCGTGGAAGCAAGCTACGCGCAGCGTCTCGTAGAGAAGTGCGGGCTGCGCCTACGCTTGAGATTGAATTACTGATTTTACTCAACTGACGCGCTTAGTGACTTTAGTCATATTTAAGTGGTGACATTTGCTAGATATCTTTTCTTGATTATGCAGAATATATTGGCAATATACAAGTTAAGTAAAACAAGGATTAAAGGATATATGAACCGCTTAAAATCTCTTCTTCTTGGTGGTTTATTAGCTTCTGTTTCAATTGCTGCTCTTTCAACTCATGCTAATGCTTCTGTTGTGAATTTTCGCAATGAACATTTAAATACTAATACTATTGCTTTTAATAACGCTAAACTAATTCGTGAGCGTCAATTGCATGAACAACAAGCTCGTGAACAAAAGGCTCGTGAATTACGTGAGCGCCAAGTTCGTGAACAAAAAGCTCGTGAATTACGTGAACGCCAAGCTCGTGAACAAAAAGCTCGTGAATTACGTGAACGCCAAGCTCGTGAACAAAAAGCCCGTGAATTGCGTGAGCGCCAAGCTCGTTTTCATCACTAAAATTTGAATTTTTACTCGCTCTGCGGTAAGCGTCTCGCGCAGCGTCTCCAAGAGTTGCTATGCCGTAGGCTTATCGGCCTCACTCCAATCAAGCGAACGTGAATAGCGTCTAGTAGAGAGGAAACCCAAGCGACACCAAACAGCGCCAAAAAGTAGACATCGCATACAAAAAAGCCCAGTCATCTCATAACTGGGCTTTTAGCTATCTCAATCAATTATTGGAAGAATAGTTTCAGACTATGCAGCAGGAAGTTCAAGATTAACCTTGACAACTTTGTTATTTTTTTTGCTCAGACTCAGGCAGTGTCAAATTCAAAATGCCATCTTTATGAGAACTACAAAAAGCATCCTGTAATTATTGCTAGTAGGGACTCGGAGCAGGTTCTCCCAGACTGTTAGTCCAGATGTCGTCTGGCAGCGAGCGATCGCGGTGACACACCCGATCAAGGTCAGGATACGTGATTGTGTCTACTGCCGCTCGGTTGCCGACTACTAGGCATCGCGTTGCCAAGGCACTGCGATTCTCAAGGAAGTGACCTACTGCCACTCCTGCTTGAAAAGTTGCAGCGTCGCCAGGACGTAATACAGTCTTTGTGTCTCCTTCAATGAGCGTGATCTCGCCTTCGAGGACATAGACCATTTCATCCTCAGCACGATGCCAATGTTTGATAGATGAACGAGAGCCAGGTTGCAGAACTTCGATGAACGCGCCAAACAGGGTAAGCCCTCCTGCTTCGCTGATCCAGAGGGTGCGATTTGGCTCATGCGCGGCGTGAGAAGGGCTTTCCTCTACGACGAGACGATCAGGAGTGATAACAGTCATACTGACACCTCTAGGAATTCTGGGGCATATATCTATTCCATTATGTCTAGTAGTTTGCCAAAGGAATTTTGCGTGGTGGCAAGCTCTTGGGCAGAGGTGCCCAGGGGCAGGGGGGAAAGAACTTGTACAAATCTCTCCTCTGCCGACCTCCACAAGCGCAATTGTGAGGAAAGCGAACTACTAGGGTACGAATCGAAGCAAAACTTCTCTATGTTTGTGCAGTCAGGTGGGAACCCTAACTGCTGGTGATGGGGTGCTGAGTAAGGAAATCTGGGGATGGAGAAAGTAGCGACACCGGACAGCCCGTCCTAGACATTGCTCTTAGGGAGGTTGTAATCCATCGCCTAAGAGGAATAAATTCTCACGAGTGATTGCCGAAAGTGCTGCTGATGTAGGCTACTGGAGTGATGAATGGTATGTTATTTATTCAAATTTATCAGGATAATATACCTCGATTAAGAACAGGAAACTAGAAAACTGTCAATTTTTCTGGAATAGAAATTAGGCTCATTGAATTAATAGTAGGGAACAAAGAAAAGATTTGCCAGTGACATTAGAAAACAAGGTTTATTAACTTGACTCCTTACAGTTTCAACAAGATCACCATGAAATTACCCATCCTATTTAAAACCCTAACTTTACTTAGTTTTTTCCTGCCTATACCCTTTAGTATGATTGCCAATGTTCCGGTTATAGCAAATACACTTAATACTCCCACAAATACTGAACAACCAAAGCGGTTGAAACGAACTTTATCAGGACATACTGCACCTGTGCGTGCATTAACCCTTTCCCCTAGCGGTCAAGTTCTTGCTAGTGGTAGCGATGATAAAACAATCAAGCTTTGGAATGCTACTACAGGTGCATTGCTTTACACTTTAACTGGACACCGTGAGGGTATTAAATCAATAGTATTTACTCCAGATGAGCAAACTTTAATTAGTACCAGTTTCGATAACACTATCAAATTTTGGAATACGCAAACAGGAAAGGAAGTTTGCACGATTTCAGAAAAAACAGGGGTGAAAGCAATGTTGTTGACCCTAGACGGACAAACTTTAATCAGTGGTAGCGGCGATAACACGATCAAATTTCGGAATCTCAAAACTCGAAAAATCGACCGGATACTCAAAGCAGAAACAACAGCACTTGCAATTACTCCTGATGGTAAAACTCTCTTAAGCGGAGGTGAAAATGGGGGAAGAATTCGGGTTTGGAGTCTGGTAACAGGTAAACAAATAGGCAGCTTTACCCCACCACTGCCCAAAAAAGAAGACCTAATCAGCGGCTCAGAGCGTGCATCAGCGCCGATTACGCTTGCTGTTAGTAAGGATGGGAAAATGCTCTTGTGTGGTGGATACGACGATAGTTTTCAATCTGGTGGAGTTAGAAGCACAGATGGTAAAGGTTTCAAAGCTTGGGACTTGAAAACAGGAAAGCTAGTTCATGATTTATCGTTCGGTACGAGTATCGATGCCTTAATTATAAGTCCCGATAGCAAGACATTTATTGCTGGTGGTTTAGGCAGGGAAATCATATTACGCGACATCAAAACAGGGAAATCAGTCATGGAGCTTACCGGACACGCAGGTGGAATTTATGGACTGGCAATAAGTAGTGATGGCAAAATTTTATATAGCGGTAGTGGTGACAAATCTGTTAAAGTTTGGCAGATAAAAGTGTAATTCGTCAGCTAAAGGCTACAAATTACAAGATTACGCAACAAGAGTAGCAACGTAGATATAAATCTTGGGAGATGATGTATTAGCTTTCTGGTTTTTGTTCATTATAATTTGTTTATTAATGCTCTTGAAAAAAACTTTATTAGTCGTATTTCTCTTAACTCTATCAACCCCCAACGCCCTAGCATTTTCTGACACCGAAAGCTATTGGGCAAAACATTGTATCCAACAACTAAAAGAGCGTAAATTAATTACAGGCTACCCTGATGGTAGTTTTCGCCCAGAAACAACAGTGACACGCGCCCAAGCAGCAGTGTTAATGCTAAATGCTTTTCCTGATTCACCAGTGAAACGTACAGCTGCGTCTTTTAAAGATGTACCTGCTGATTATTGGGCAAATAAAGCAATTTCTACCGCTTACCAAAAAGGATTTTTTTCTGGTTATCCTGGTGGTATTTTCCAGCCAAACCAACCAATTCCTCGTGCCCAAATCATTGGTGTTGTAGCTGCGGGGAAAAATTACAGCCCTTTACCTAGCCCAATGCAGACATTACAACAATATTTTAACGATGTGGGGCAAATACCTAACTATGCCCAAAATGCGATTGCATCAGCCACGATTAATAGTATTGTTGTCAATTATCCCAATGTCAAACAGCTAAAACCACTACAAAGCGCGACTAGAGGGGAAGTTGCGGCTTTAATGTGTCGGGCGCTGAATATTTACACGGTTCCCCCACAATATATTGCTGGAGTCGAAGTAGACAGCCAAGAAATACGTCCTTTACCAGGAAAACTTGATCTTATTCCCACCTTCAACAGTAATAGTCCTGAACTGGTGACAACTGAAGGAATTTTACTATCAACTTTTCCCCCAGATGGGAAACAAGTACATGAAGCACATTTAAATTATCCCTTTGAAGGCAGATTTGACATATTTGCTCATCATATTGTCAGGGCAGAAACACCAGCCCAAAGCCTCACTGTATACCAAGGGATAATTGTACATAATCCAGGAAATGAACCTGTGACAGTGCAAGTATTACAAGCAGCTAGTTACCTTACCAAAGAAGCACAATTTATTGCTTTAGCTGATATGGTTGAAAATCCCCAAGGTACAGTTTACTCTGGGCCAGGCGATCGCACAATGAATGATGTACTGCGGGGAGTTCGGCAAGAGATTTTTCCCGAAAAGCTGGTGATAGAACCAAAAGAAACTAAAATCCTAGCAAATTTACCAATACAGGTACAGGCTCCTTCTTCTAACGGTCGTACTACGATGATGCGCTTGACAAGTAGTAGTCCAGTTTATATCGCAAATTTAGTCAAAAATAGTAATATTTCACCTACTTTAGGCGAGTGGCAAGAGCTTTTGGATACAGGTAGTTTAGCAGGAAAGCGTGACCCCATTCCAACACCTCTTGACCCTCCTAGAGAACCAACGGTATTTAGCCGCGTCGCTGGTGTATCTCAAGGAACGCAATGGAAAACACAAATTACGGACAATTCCAATGTTTCCGAGTTAACAATACCCTCACCAGGAAAGGCGTTTTCCTATCCTTTGGGAACTGTACATTTAATTACTCTTAGCACTGGACAAATTCAAAGTGCAGCAATGTTAAAACGTTATCCTGATACGGCCTACTTTGCTCACAGTAACTATGGTGTTGAGTACAATCTAACTTTGCCTCTAAGAAATATTACGAGTGAAACCCAGACTATAACTGTGTCAATACAGACTCCTGTGAAGGATGAAGGGGGAACAGATAGACTGCTATTTTTAAAACCAGGTGTAGAACAAATATTCTTTCGGGGAACGGTGCGGGTTCGTTACATCGATGATAATGGTGTGGAAAAGACGCGCTATGTGCATTTGGTACAGCGTCGGGGACAAAGGGGTGAACCATTGGTGACACTGAAGATGTTGGCGAGTGAAAAGCGACAAGTACAGATAGACTTTTTGTATCCTCCAGATTCTACGCCACCACAGGTTTTGACGGTGAGAACAAAGAGGTGATTTAGGATCAAGTCTCGTGCTTTACGCAAAAAAAACGAATATTCTTGAAGTTGGCATTACAAAGGATAGAGGTCAGCATCAGCTAGCTTATTACAGACGGCAACCGCGAATTTAAATAGATGCTTTGGAGAAAAAGACAAATCTACTTGCATTACAGAGGTACGTAATCTTACATTAATTGCTTACTTTTTATCAACTGGCATTCAAAATAAAGCAGGTAAGGAAGATTCGCTGTTAAAATACCACCAGTCGGCTAAATTAAACGAGACATACAGCTTATGATTACTCAAATGATGGTTCAACCTTCATTCTGGGTAGAGTCTGGAATCAAACTCAGTAAAGTTAGGGACATACATCTGTTTAAATTTACTGAAGAATTGCAGTCTCGACTGGAAGAATTATCTGAGAAAAAGAAAGCTGGATTGCTAACCACAGAAGAAGATGCTGAATTGGCAGGTATATTAGAACTAGATAGAATTTTTACCTTGCTCAACGCCAAAATCATTTCTGAGTCATGACGGTCAATGATTCGACCAAAAAATTAGTCAGACAAAGAGCGAAATTTCTTTGTGAATACTGTCATTCTTCAGAAGAAGCAAGTGCTGCTCTATTTTCTATTGACCATATTATCCCACAGTCTCTTAAAGGTTCGGATGACCCTGATAACCTGGCGTTAGCTTGTCAGCGCTGTAACGGATATCGCTACAATTTCACCACTGGAATTGATCCAGATACAGGACAGATGCTACCTTTGTTTAATCCACGTCAGCAGAAGTGGTCAGACCACTTTATTTGGTCAGGAGATGGTCTAAAAATTATTGGCATTAGTTCTGTAGGACGAGCTACAAGTAATCGTTTAGACCTTAATGATGAACGTCATAATGAAGGGTCTATTGTCAAAGCTCGTCGTCTTTGGCTCAAAGGTGGTTGGCATCCACCTGATGAAGACCCGCGACAAGTACAAGAGTTTTGATTTGCAATTTCCTTAACTGTATGAGTAAAGGCAAAGTTTTTAGGCTTAGAGAAACTGATAACGGGGATTTAGCTTAAGTATCAAAACGAGCTGCATGATAGAAGCAGGAAAGTTAAACCCCCAAACTTTGTTAAAAAATGAAATGGTTAATGGTATTATAGTACAAGCGAACTATCAAGAGATTTGTGGTTATTTAGGGCAAAATCACAAAAGCTAGAAGAAACTTTATCTATTCTTGCCCAAATTCGACAGCATTCGACAAGTGAAGAAGGGATCATAATTTTACGCCAAGTCCTCAAGAGTAAATATTCTATAGCTGTTGCCCAAGCAGCCAAGATAGTCGGCGAATTTACTATCACTGAGTTGGTTGCTGATCTTGTAGAAGCTTTTGCTCGAATGATGGTCAAACCCGCACAAGTAGACCAAAATTGTCTTGCCAAGAAAGAAATAGCACAAACACTGTATCACTTAGAATACAGCGATGAAAACCTTTTTCTGCAAGGGATTCGACATATTCAGATGGAGCCAGTATGGGGAGGAGTTGAAGACACTGCTGCCCATCTTCGGGGTATATGTGCTTTAGGTTTAGTGAGAATGAACTACTCAGACGTAATGAACGAATTAGCCGATCTACTAGCTGACCCCAAACCAGAAGCAAGAACTGCTGCTGCAAAAGCGATCGCCTATACAGGAAATCCCCAAGGTGTACCTTTACTTCGTTTGAAAACCCGCATCGGCGATCAAGCACCACAGGTGATTTCGGAGTGCTTCAGTGCTTTGTTACAACTAGCTCCAACTGATTCACTTGCAATAGTTGCTAGTTTTCTTTTTGACCCAAAGGAGCAAATCTGTGAGTTAGCAGCATTGACGTTGGGTGAATCACGATTAGAGGAAGCATTCGATCTTCTCAGAAATTGCTGGGGGCAAACAAGGAATGTAGAACTTCGCCGCACATTGTTACTAGCAATTGGGATGTTGCGACAAGATAAAGCAATAGATTTCCTGATTTCACTAGTGGCTCAAGGAAAAGACATCGATGCAAAAGATGCGATTGCAGCATTGGGTATTTATCGAGAAGACCGTGAACTGTGGCAGCGAGTTGAGCGAGCTAGTGAACAAAGAGCTAATCAATTGGGACTTTAAAAGCGTTGAGAATGTAGGGCTATGCATAAATATGAATTTTTCGCCTAATTTTTATGAGCTTACTTCTGAATTGGCGAAAAATTCTTGTGGCAGCGTCTGCTTTTAATTTAGTCGATTTTAAGATAAGCTTTGTTGATTGATAAGTCACTATAGATTGCAAAAATACATCGTCATGAGTCAGGGTGTATATCCAAACAATTGGAAACAAATTGCAACAGCGCTAAAAGCTGACTGTGATTGGCGTTGTACTAAATGTGGTAAGGTCTGCTTACGTCCTGGGGAAAAACCACCTGATTGGACAAAATCCCAGCGCAAAGCTCATACACTTCAGGTACATCACTGGAATTGTGACCCTGGTGACAATCGGCTGGAGAACTTGGCTTGCCTGTGTAGTGGCTGTCACCTTTATTACCATCGATTTGGACGCGGAAATATTTCTCCTGGACAGTTGTCACTGTTTGCCCAAAAGAAAGTTAGCTAAAATTTGACCGATTGCAGATGTGAGCGCTCACGCTTTTTGAGCATTGTTAATTTTCATTGATGCTATAAATTTATTCCTTTTTCCTTTCTTAATAATAAGGTAGTGATGCTAGATTTCCTTTATTTGCAAGGTGACTTATGAACAAAGGCGAACTAGTCGATGCTGTAGCAGCGGAGGCCAACGTCACAAAAAAGCAAGCCGATAAAATTCAATGGTCTTTAACACAGCGAGATGTTAATTTGATTGAATTACTGATGCCTATATGGTCATGGTTTTACCGTTACTATTTTCAAGTAAAAACTGATGGATGGCATCACATACCAACAGAAGGAAAAGTCTTACTGGTTGGTTCCCATAATGGCGGAATGGCTTCTCCAGATTTAGTAATGATGATGTATGATTGGTTTTCTAGATTTGGAACAGAGCGTTTGGTGTATGGTCTAATGCACCCTTATGCTTGGAAAGTGAGTCCAGAGATAGCCCAATTAGCTCAGAAAGTTGGAGCGATTGTTGCACATCCAAAGATGGCCAGTGCAGCTTTTGAGATGGGGGCTAGCGTTCTGGTGTATCCGGGAGGACAATATGATATGTTTCGTCCTCATAGCCAACGCTATAAAATTAATTTTGCTGAGAATAAGGGCTTTGTCAAGCTGGCTTTAAAACAAGAAGTTCCAATTATTCCAGTGATTTCTGTAGGCGCTCATGATACGTTGATTGTTTTATGTGATTGCTATGCAAAAGTCAAACAACTACATGAGTTAGGATTGCCGTGGCTTTATCAAATAGACCCAGGAATTTTCCCAATTTATTTAGGTTTACCTTGGGGCTTGTCTATTGGGCCTCTGCCTAATATTCCTCTACCTGTGCAGATTCATACTCGTGTATGCCGTCCAATTACTTTTGAAAGATATGGTCAAGATGCAGCTAAGGATCGTAATTATGTGAATGCTTGTTATGAATTAGTTCATAACCAAATGCAAGAAGAGCTAAATCAATTGGTTATAGATACTCAAAAATCCCCATAAAATCAAAATATTAAAAAAAACTCGGAGAAAAATATGTAAACAATTTGGGAAAACCTTATTTATAGAAACTGCATAAAAACAAGCTTTAAGAACAGTTACATCAGTGAGATAGTAATCCTATCACTGGCTAATTCTCCGATTTAGCTGCAAATCCAGGTTAAGACTACGGATTCTGCCGAAGCCCTAACAACCTTGTGGAACATAAAACTGCAAGGGTAGCGGATGTAGAGCAATATTTAAAAGTCAAAAGTTTAAATGGGGGCACATCTACCCTCATTTTCAAGATGGATATCAAGTAAGCGTGCGTTAGAATTGAAGTAATGGCAACTTGATTGATTTGAAGCTAGATTAAAGAATCGAGGGTAAAAGTTGCTCACAGGGCAAAGTTTAATAATTGGGTCATTAATAAGTTGTTTATACAGCATTTGTGATCAGCGATAAAAGTACTGTATGCAAACGGTTTAACCCCAAAATAGCGATGTAGAGTTTAATATTTGCAGGTGTTAAAAGTATGGCTAAGGTAACAATTTCTATTGGGCTAACTGATGCAGAAGTCAAAGCCTTATCAGCAATGCAGATTTCGGAAAATGAGTCATTAAATCACACAGCAACAAGATTGCTCCAGGGAATATTGGGACAGTCAAAAACTGGGCTGGCATTATCTAATGGTGATGAGATTAAGGAAATAGTTAAGCAAGAAGTAAATGTTTTAGCTGCGTCTACACCTGATGGGGAAGAGATAAAACAGGTGATTAGGCAGGAATTAGCCCAAGCGATCGCTCAGATTAAGGGTTTAATAGATGAGCGTAATGGTGGAGTTGCCCTACAAACACAAGAGGCTGTTTCCGTTGAGCAGCAAGTCCTACCAGATTATTCAGCAATACGCGAAAATATCCTTTCTAAATTGAAAACAGGTAAGCAGTCAGCAGCCAAGGCAATTGACGCTTTTATTGAGTCACTGGGTGCTGTAAAGTCAGAACAACAGCCAGCAACTGTGGAATTAGATGTAGCGAGTTAGAATTTTTGTGCTGGCGACTATTAACCAGTCAACTTAATCACACCTTGGCTGACTAAATGTTCAAGCTGAGAATGATGCTGTGTTTGCTCACGTAGCAACTTGAGTTGCTCGTAAGTGACAATGTGTAATCCGGGACGGACAACATAACCTTGAATGCTAATGCTTTGTGGTTGCTGGCTATCGGTGCGGTTGTAGGAAATTGAAGGCATATTTACATTACGTAAGTTAGAACTGATTAGTAGAAGAAAGTTTAATTCTTCATTCTCTTACAGCTTCACACAAGTTCCTCTTAAAAGGTGATTATAGAAGCCTATTAGATTGCTGGTCGCTCCTCTAATAAACCTTGTACAAAGCCGCAGAAATCACCCGAAAAAGCGCAGACTGTAGATTAACCGTTCGACTACAGGAGATGCTCTCCTAAAACTCAACTGGCTTTGCCTTTAATTCAAAGCCACCACAGAAGTAGCCGTACATAGTTAATTTTCGTATGCTGCTTGATTGTTAGTCGTTTTCCCCTTATCCTCACAAAAGGTAGTAATAGTAAAGTAAATTTCCTTTTCAAGGCAATACTTCAGGGTGATTTATGAACAAAGGCGAATTAGTGGATGCTGTAGCAGCAAAGACCAACATCACAAAAAAGCAAGCCGATGAAGTCATTAGTGCTTTTTTGTCAGTAGTTATCGAAGCTGTAGCGAATGGAGAGAAGATAACGCTGGTAGGGTTTGGCTCATTCGAGCGGCGCGATCGCTCAGAGCGCGAAGGGCGTAATCCGAAAACCAATGAGCCAATGACTATCCCAGCGACCAAAGTGCCTGCGTTTTCTGCTGGGAAACAGTTTAAAGAAAAAGTAGCGCCATAGATGAATGGCTTTACCACTGGCAATCTAATCCGATGCAAAGCCATAATCGATTAATTCAAGTATCGAATCGACTATGAAACTTTGACTGCTTCTTAGGGAGTAACGTTACTACAATTCTGGTATTACTCCCGTATCAACAAATCTGTTTCTGTTAAAATCGCGTCTTCCAGCACGTAACTTTTGAGGCAGTGCCATGTGTGCAAAGGGATTTGGACAACCCCAACCCACCAAAATCGATAAACTTGTTGAATCTGCGGTGCGTTATTGCCACAAGCGACACCCAGAAGCCTTAGACCAAATTTTTGACAATCTGCCTGTTAAGCTCAACCAAGAAGTAGTAACAGGGATTTTGGCAGCATTGCAGAAAGATATTGACACTTTGAGTTGGTTTTGCGGCTATATGGCATCAGAAATCAACCGCAGTGAGGACAACCAAAAGCCTCATCATCCCATCGCCGAACTTAGCAAAACTCTGATTACATCGGGGATGGAACCGTTTACTGATTTTATGCCTTATCCTGGTTGCCGCCTCGTCATACTCAATTCGGAAAAATTTGAATCATTACCAAAGTCAGTTCAAACCATAGTGCAGCAGGCTTTTGATATTAGAGAAAGTAGTGGGACAGAGGCACAAACGATAAATGATGCGTTGCTACAAGAGTTGATGGTTCAGGAGTAAGTAAAAAATTGGAATGTTATGGAGTACCCACACGCCAACTCTTGGAGACGCTTTGCTCCCGCAAGATCCACGTTCGCGTAGCGTGCCGTAGGCAAGTGGTACGGCATCGTCTCCACTTATAAAGCATAAATAAGCCACCCTACCCAAAAGGCTGCCCCCACCGTTCCCAGTTATCCTTATTAAATGGACTGCGCCACTTCAAAATAAGGTTCAACTCTAACTCTTGCCGTGTGCGTCGATCAACCGGAGCATCCCACCAAAATGCGGCGTTGACTGCTGTTTGTAACCCATAGTGATAATGTAAATCCTGGTAGCTGGCGATGTAATCTTTGCAGGCGTGTATACCCTGCCATCGCTTGTTACTGCGGCACTTTTCGCCTACGTACAAAATAACAGAAGCCGCCGAGTCTATGATGAAATATACACAAGCTGACCCAGGACTATCAACTGGCATTCGATAAAACGACATTGGCACAAGCCGCAGCAAGAGTGGATCAATTTGGTCTGGGTCGCAGTGCTTAGGGGTAAGGTCAAATAATGCCGTCTGCTGTGGTGGTTTGTTTTCTCTCACCTTATGCTGATATTCAAAAATCTGAGATTTCCACTTCAACAGCGCCTCAAGACTCATTACCAGTGTCTCTGCTGTGCGTGCTGGTGTGACAGTCAAATCAGAAAATAAATTTAGCTGGTTGGGTTCCAAGGTGATTAATGGGAATGTACAAACCAGTAGATTATCGCCCACAACTGGATGGAGTCAAACCTGTTAGCAGCTTACTAGAGCGATCGCTGTGTTGATTTTGGGCATTTTAAAATAGCGTTTCCTCAATATTGCCATGTTTAAAGGATTTAGTCGCCCAAAGAAAAAATCAGTGCTTGAGGACAATGAACTGACCACAGGGATTGTTCAACATCCAGTTACGGGACTTTGGCAGACATGGATATCATTTACAGGTAATGATATTCAATGTATTACCGCCCATGCGAACCCTGATGATGCTGACCGGGTAGCGAAACAGATGGCTTCGGCTTGGAGTGAAGGGAAATATAAAACTGGGGAAGAGGTGACAGCTTTTATCCAATCACTGCCTACTGATGCTGTCATAGACCCATTACCCCAAAATATTGTGATGCAACTGAGCAAGCAGGCATTAAGCGCAAGAAAGTAAGAAAGAGCGATGGCTTTACAGAGTACGTTCAATTGCTGCCAAATTGGGCATTTCAAGGAAGACCGTGGGTTTAGGAATCTGGATCGATGCAGTTGAGATGCTCACAGCCAAAAGCTTGAGTCATCATTGCAGCTAGCTGTTGAGAAACTTGTCCATCAAAGTTGAGTTTGAGCATGATTTGGTCATAGGTTTGTCCCTGGGTTATCTGCTTTGCTATTTGCTCAAACTCTACCCAAGTCAAATCACTCTCAACAAATGCTTTCGCAAGAGTAATTACCAGCTCCTCATAATCATTGTCTTCCAGTTTTGTCATCATTCGGTGTTCAATGTGAAGCGAATCATCGAAACAGTAATACCAGGATTTCGGTTGCTGTTTAACTACCTTTCGGAAAAAGTCTTGTTGTTTGGAAAGGTTAACAGCGCGATCTGCTTCACTACATACCATTAAAATAGGAGCGGAAACACAGCCTTGAGCCTTTTCTGAAACTTCCTTTGCCAACTGAAGAAATATCCGTAATGACTTGAGACAAAAACCTTTATAACCAAAATTGCCAGATGCGTCTTTGTTAAACCATTCAAAGTAAATTGGTAGGATTTTGATAAGTTGATCTAATAGTGAGTAACGGCTAGCTAAATAAGGGGTAAATAATAAAGTGCTGTCAATCTCCTGGGGATACTCTAAAGCTAACCAAGCAGCTAAAGTTCCACCTGTTGACAATCCACCAATTACAACTTGTTGGCCTAGTGTTTTTGCAATCTGCAACCATTTGAGAAGAAATTGTTGATATATCTGAATATCTGTTGGGAGTGGTGGGGGATTTTTACGGCTCCAGTTTCCTGAGCGTCCATGACCAGGCTGTAAAGGAATTAGAACGTTATGTCCCTTTTTAAAAAAGGCTTGACCGAGCGGCTCAAACTGGTAGGGGCCTGCTGTAAAACCATGCAAAAACAAAAAAACTTTTGACGTGAAGTAAGGATGAATTAAAAATTTGGAGCGACAAGCTTCATTTTTTAGACCTACTGTGGACTCTAATTGGTGAACTTGCTTCAGGATTTCTGCTGTATTTGTTGGGATGGCAACTTTCATCTATTATTTATTATTTTTGTATGCAACATACCTGACTTTATTAATTAAGTAGTTATTTTGGATCTAGCAGAGGATATATTTTTGAGTTAGCCTGTCAAAAGTGAAAAAGTTTTTTCAAGTTGGATAAGCATCCAATCCATTTTCTTTGACACCAAGCAGCCCCGTTAAAGTAGCGACACCGGACAGCCCGTCGTAGACATCGCTCTTAGGCAGGTTGTAATCCATCGCCTAAGAGGAATCAATTCTCACGAGTGATTGCCGAAAACCCTACTGATGCAGGCTATTGGAGTGATGAATGGTATATTATTTATTCAAGTTAATCAGGAGAATATACCTCGATTAAGAACAGGAAACTTAAAATGAGAATTTTTGTTCCAGGCCGTCTTTGTTTGTTCGGAGAACACACTGACTGGGCAGGAGAATATCGCAGTGTTAATCCTCTTATCGAAAAGGGCTACACCTTAATTGTTGGTACTAATCAAGGAATTTATGCCAATGTCTTACCAAATTCTACTGAATTAATTATTCGTGCTTCTCTCAATGATGGCAGGAGTTATGAACCACTCAGATTAGCTATGGAATCTAATACTCTCAAGTCCGTAGCCAAAGAGGGCGGTTTTTTTAGTTATGCTGCTGGTACAGCTTATCAACTTCTGACTCATTATGGTGTTGGCGGACTTGAGGTTGATAATTATCTAACCGACTTACCCATCCAAAAAGGATTATCTTCGAGTGCTGCCTTTTGCGTTCTCATTGCTCGGTCTTTTAATCGTCTGTATGACTTGAAGATGACAATTCGTTCAGAAATGGAGTTTGCCTACAAAGGAGAAAGAACCACTCCTAGCCTTTGTGGTCGTATGGATCAGGCTTGTGCTTATGGAAATCGCCCAATATTGATGATATTTGATGGTCAAAAAATCGACCTACTTGAATTGAAAGTGAGTCATGATTTGTTTTTTGTGATTGTCGATCTTGGCGGGAGCAAAAACACACAAGAAATACTAAGACGATTGAATCAGTGTTATCCTTTGGCTACTAATTCAATAGAGCAAAATGTCCAAAAATATTTTGGTTCTATTAGCTCTGAAATTACCCAGGCAGCAGTTGAAGCAATACAACTCGGAGATGCCCAACTTCTTGGAGCTTTAATGACAAAAGCCCAAGCGGAATTTGACCGATACGTAGTTCCAGCTTGTCCCGAGCAATTAACTGCAAAAAAGCTACATCTGCTTCTCCATCACGAGCCACTTAAGCCTTATATCTTTGGAGGAAAAGGCGTAGGTTCTCAAGGGGATGGGACTGCACAACTGATAGTTAAAAATCAAGAGAGTCAAAGAAAAGCTATCGAAATTATTAAGCATGATTTTCCTCAAATGCAAGCGTTACAGTTGACTATTTCAAGGCTACCAACTCCGATGATTGACTTAGCTGAGGACAAAAACCAGTATGGGGATGTTTATTAACAAATGCGTTTAATACTTTATTCGCGCTCAAAGACAAAAATAATTGAAATCGGTTTGTTCGTTTTGGGATCGCATGGCTCATATAAATTTAACAATCGGTAATTTAAAGCATGGAACTCGTTGATCCATGATTCGAGCGTTCTGAAATACCAAGGAGTAGGGTGAAATGGCTTATCTGAAACTGTTTGCCATGAAGTTTCGCGCCATGCATTGGAGTATGTAGAGTCACCGCAAGCAATTATCGGATGAAGGGTTTGAATGATTATTTTGCCTTTGGACTCTAACAGGCTATGGCCTGCCTTGGCGATCTCATCAAGAGCGCATTCGCCTATAATTGAAAAGTTGCAGATAAAGCAAGAGAAATAGCTAATTGTGCTAAATCTTTGTGATGCAAGATCCGAGTAGGAACAGACAACAAAGCGAGAATCACCACTATCCCTTGCTGCGTCAATGAGAGCGGCACAAAAATCAACACCCCATCCATCAATTCCTAAAGAAAAAAGCTGTCGAGACAACCATCCCTCACCGCATCCAATGTCTAAGAATGTTCGTGGATTAAGTTGGCTTACTGCTTTGAGTATAGCGGCATCAGTGGCGATCGCACGAGAATAGATTTGCTGCTGACGAATTGCTTGTGCCCATAACGAAGCATTCATCTGCCATGAATCAAGGATTCGTTTTTCATTCTTGTCCATACAACGCGGCTCAAATAGTACGAACAATCTTCTCCTTTAAAAAGATAAGCGATAATGTAGCCAGATGTAGGAAGATTTTCACTATTTTCAGGAATCGCAGTTCTGCCCAAGAGCGACCACAGTTGTAACTGATGGCAACAGAGGGCTACCAATTATTTTTAGTGATGGCAGCCAACAGAACATGGTTGCTGGCGATGGTGTGCTGATGAGAGTAAACCTGTAAACCTGGGGATAAATAAAGCGACACCAGACAGCCCGTCCTAGACATTGCTCAAGCAGGGTGTAGTCCACATCGCCTCTCCAATCAATTCTCTCTCTTATTGCCGAAAGTTCTGCTGATGTAGGCTATTGGAGTGATGGGGTGGGGTGTTGGGGGAAATCTGGCGCGAAGATTCGGTTTGGGAGTTTTTGTGTTAGAAAAGCTACTGTTGAGGGAAAACTGAAAACAAGACCCTGTTTTGAAGACTTTGATTGTAATTCATCAGCCGAACGCTACAAATTACACAACAGAATTGGCAACGCATACATGAGTTCAATTCATAGTATTTGTGTACTATTTATTGACAAATAAGTACTTGTTGCTAAAATCTTTTAACAAGTCAGGGTAAGTTAAGTTAGTAATTTTTTAGAAATGAAATTGCGAAAAAGCAATCTAATTAGGGATTCTCATGCAAGATTTATCAAATATTGACTTATTTTATGCTTATTTAGACTTAGAAATTAATACTGAAAATAATATATACCGCATCGGATTGGTATCTCTGAACTTAACAAAAAATTTCTATCAAGAGAATCTAAATCAAGCTTACGAAGAAATGAGGAAGCTGAAAAATAGTAATTTATCAGTATGCGGTCATAACTTCCGCCGCTTTGATTACCCTTATCTGATTGAGCAAGAACCGCAATTATCTTCTTGGCATATAATTGACACTTTAGAACTATCAATACTCGCTTTCCCTCTACAGCATTCCCATAAGCTAAATAAAGACTATAAGCAAAGTGAATATTCAAGTAATAATCCCGTAGAAGACGCACAGGCAACTCGATTATTACTTGGTCAACAATTAGAAGCACTATTTAAAAAGCCTGATGAAGTACAACAGGTATATATTTGGCTCCTGACTTGTGGTTGCGAAGATGCAGACCTTGCATATCAACAATTTTTCAGTGATAACCTTGGTTTGAAGATTGAACAACCCGCCATAGAAATGCTGCCAGAAACAATGCTAAAGGGAATAAATCAATCCTATTTGCAGCAGCTAGGGTCTAGTCCACAAACTTATGATTTTGAGACAAGATTATGCGTGGCGGGATTACTGGCTTGGAACTATGAGTGCAATACCAATGAATCGAAGCAGGTTTTTTGTGATTGGCTCAGACATTTAAATGGTTTTCAAGCTGTACTTGAGAATTTGCGTCCTTTAAGTACAGATGAATTCGCTATCAGCTCTTACTTGGAATATTTTGAAATTCCCAGTTTTCGACCTTTGCAGGAAGAAGCTGTCCAAGCAATTATTAATAATGAGCGTCCACTTGTTCTCATGCCTACTGGTGGTGGTAAATCTTTATGCTATCAATTACCAGCTTTCATGTTCCACGAAAGGCACAAAGCACTGACTGTTGTCATTTCACCGCTACAAGCACTAATGGCAGATCAGGTAGCAGATTTAGAACAAGCTGGGTTTTTCTTCGCCACCTTCATTAATGGTAATCTCTCAGCAGCAGAACGTCGTCAGCGATTATCAGAACTGCGTTCTGGTTCCAAAGGTTTGCTGTACATCAGCCCTGAGCAATTGCGGTCAATGAGTATTCGAGCATTGTTAGAACAACGCCCTCCGGTTCTTTGGGTGATTGATGAGGCTCACTGTGTTAGCCAATGGGGCCACGATTTTCGTCCCGATTACCGTTACATCCCGAAATTTATTTATGAATTATATCAAGAGCGGCAGCTTGCAATGCCTTTGTTAGCTTTAATGACAGCAACAGCAACTGTTGCTGTTATTGAACCCAGATTCCGCAGGTGCGCTCGTAAATGCTGTATTTTTGAAAATGACCTAAATGCTGCATTTTAGAAGCATGACAGCATCATTAAATATCAGGGTACAGGATATTGATCACTGCGGCATAGTCGCAGGCATCTGTGATGAGATGAATTTAGTAGAACAAATTAACCGACTGCTGGGAACTCACTCTCAAGAAATCATCAGTGCAGGTCAAGTTGTAAAAGCAATGATTTTAAACGGATTAGGATTCGTGAGTGCGCCGTTATATTTGTTTGAAAAGTTTTTCGTAGGCAAAGCTACCGAGCATCTTTTAGGAGAAGGAATACGTCCAGAACACTTAAACGATGACCGTTTGGGTCGAGTATTGGACAAATTATATGAGGCGGGACTAACGGAAGTATTTGTGACAGTGGCGCTTTGTGCAGCACGTAAATTCGGGGTAAAAATGGACAGCCTGCACCTTGATTCAAGTTCATTCCATGTTGATGGCGATTACATTAATAACGCAACAGCAGAGGATGCGGAAGCAGGAGGAATCGAAATTACCTACGGCTATTCAAGAGATCACCGCCCAGATTTGAAACAATTTATCCTGGACTTAATGTGCAGTGGGGATGGAGATATTCCCTTGTATTTGAGGGTCGCAGACGGTAATGAATCAGACTCAGCAATATTTGCGACCATCATCGCTGATTTTAAGCGGCAGTGGCAAATAGATGCTTTGTTTGTTGCAGATGCCGCACTTTATACGGAAGAGAACTTGCAACAAATGAAACATTTACGTTGGGTATCAAGAGTCCCAGCTACCCTAACTGCTGCAAAAATGCTGTTAGAAGACATGCCAGAAGTTGCATTTAATGACAGCGCAATGCCTGGATATCGAATTGCACCAAGTTGTAGTGAATATGGTGGTGTCAGACAGTCCTGGTTAGTTGTTGAAAGTCAAGCCAGAAAAGAAGCTGACCTCAAGCAGTTGGAAAAACGTTTAATTAAAAAGTTATCAGTTGCCCAATCCGAACTTCGGCAGTTGTCAAACCAAGAATTTGCTTGCTCAAAAGATGCTCTGATTGCGGCACAACGGCTCAGTTCTAAGTTGCCCTTACACCAACTGGCTAATATCCAGGTTAAGGAAGTAAAAAAACATACTGGACGTGGTAGACCCAGTAAGGATGCTGCCCCTACCTTTTACTACCAAGTCGATGCCACGCTAGAGCCCAAGGAAATAGCCATCGCCATCGAAACCAAACGCGCTGGAAGATTTATTTTAGCGACCAATGTCCTCGATGCCGAAGAACTCAGCGATGAAGATGTTTTACGTGAATATAAGGCACAGCAGTCTACTGAGCGTGGTTTCCGATTTCTCAAAGACCCTTTATTTTTTACTTCCAGTGTCTTTCTCAATTCGACTGAGCGAGTTGCCGCATTAGCAATGATTATGGGTTTGTGCTTGCTTGTTTATAGTCTGGGTCAAAGAGCTTTACGTCAAGCCTTAGAACGGGCAAAAAAAACTATTGATAATCAGTTGGGTAAACCAACTTCTACTCCCACCTTACGTTGGGTGTTCCAATGTTTTATGTCAATTCATTTGGTTACCGTCTCCCAAATCAAGCAAATTGCCAACTTAACCCATGAAAGGCAATGGATTCTTCAGTTTTTTGGCGCTCCTTGTCGAAAATATTATCTTCTTTCTTAACTAACCTGCGGAATGTGGGATTGAAGATATTAAAGAGCTATTTGCCCAACATAAACTAAATATTAATCGTAAAATTGATGGGGCAATAACAAGAGATAATCTAACTTTTAATGTGATTTCAGTAGCAGGGAATAAAGAGCAAGTTTTGTTGAATCAAGTAAAAGAAGCTCTTAAACTAGGTGGTAGTACACTGATTTACACTACTACACGCAAAAATGCCCAAAAGCTAGCAGAAACTCTTAAACAAAGTCACATTGAAGCAAAATATTATCATGGGAAACTTGCAAAAGAACAAAAACAACAAGTTTTGCAAGAATTCAAATCAGGTAAATTGAATGTAGTTACTGCAACTTGTGCTTTTGGTATGGGCATAAACCGTAAAGATGTACGCGCTGTCATTCACCATTGCATGAGCGCCAATTTAGAAGGTTACATCCAAGAGGCTGGACGGGCAGGACGTGATGGAGAGCCAGCAGTTTGTACTTTACTCTTTGATCCAAAAGATGCTGATACAGTTTTTTGTTTGCAAAGTTTGAACCAACTGAGTGAACAAGATTTGAAAAATGTCTTGATCTCGACTAGACATATCCGCGATCGCACTTTTGGCAGCGCTAGAGATGATTGGTTTTGGGTGACAACCAATGAAATATTTGAATCAGGTGACTTTGATGAAGAATTTGGTGAAGAATCAGAACAGCAAAATACTAAAATAAAAGCAGGATTGCATTACTTAGAAAAATTTGGTTTATTAGAACGAGCCGAGAACTTTTCAAGCTTTATCGAATTTGAACTAAGCCATAATACCTTTGCTGAGTCTATAGAGCAGTTTGAGGAATACAGCCGGATGAAGGATTTATCCCGGTTTGAAGCAGACAACTTTGAGCGGCTGATTCAAGCAATGCACATAGCGAAAGCTTATTGTAATAGCAATGATCAACCGTTTCCCCTCGACCGTCTCAGTGATGAAGCTGGAATTAGCTTACATGACCTGACTGCCAGAATCCGTGAACTGCAAAAGGCTGAAGTCTGTTCTTTTGAAATACCCATTACACTTGTGATTACCAAGGGTGTAAGAGGAGATGCCCGTAATAATCATGAACGCATTCGCCAGTTAGAAGACGAATTACTCAAAGTGCTTAATGAGTTATTTGGTAATCAAAATGAAATACAAATAAATCTGCGTGGACTTGCTTCTCGACTTGACCCAGACAATAGTAAAAAAATCAGAGCATCCAACATCATAGATATTTTGGAAGGTTGGGTTGCTCAAAAATGGCTAAAGTTAAGTAGAATTTCTAGTGATGTGGTTCGCTTAGGAGAAATGGAAGTTGCAGAGCATTTACCTGAGCATAAAATTCTCACAACTACAGTATTGGAAGTTTTGTATCAAGCATTGAAAGATACAACAGGGGCGAGATTACCTCTGAAGTACGAATTAGGTAAACTTGCTAAAGAAGTTACCCAAAAAAGCCAACTTGACTGGAATAATGAAGAGTTAGAAGTTATTCTTTTGTGGCTCCACCAGAGAAAAATCATTCGATTAAGTGATGGGCTTAATCTCTTTCAACAGTCGCTGAAAGTCCGTGTAATAAAAAACGCAAGTGTTTCCAGAGTAAAACGCCGTTACCCTGAAGTTGAAGCTCACTATGATGAACAAACTCGTCGCACCCATTACATGGTGAAGTATGGTCAGTTAAAGTTAGATGAACAGCGTCAGCAATTTGTTCGTGATTACTTTGGCACAAATCAAGAAGAATTCGTTTCAAAGTACCAATTTTTGGCACAAGAGATTACCAGACCGATTCTTCCAGAAGACTATAACCGTATTCTAGAACCGCTTAACCCTGCTCAAAAAGAAATTGTTTTAGCTTCAGACCCAACAATGGCAGTAATCGCAGGCCCTGGTTCTGGCAAAACAAGAACTATTGTTCACCGGATTGCTTATCTTGTAAAGGTTAAGCGAGTTGAGCTGAAGCGTATTCTTGTTTTAGCTTACAACCGTAATGCAGTTAGAGAATTACGGTTGCGGTTACGTAATTTGATTGGCGAACAAGCATCACGAATTCGGGTCTTTACTTTCCACGGTTTAGCCTTATCACTTTTGGGACGGACGGTAGGTGAATACAGAGGAACTCAGACAATAAATTTTGATCGGCTTTTGGTTGAAGCTTGCGAATTAATTGAAAAAGGCGAAGAATTTGAAGATGCAGATGAAGATACTCAGGCACGACGAATTCAATTATTAGGAAAATTAGAATATATCTTTGTTGATGAATACCAAGATGTAACTGAGAAAGAATATCGTTTAATTAAGTCAATTTCTGGCTTAAATCAATCTGAGGATAAAACACAGTCGGTACAAATTAATCTCTGTGTTATTGGAGATGATGACCAAAATGTTTTTACGTTTAAAGGTGCCGATACTAGATATATCCTTCAATTCCAAGAAGAGTATAAAGCAAAACGATTACTACTTAACGAAAATTACCGCTCTACAGAAAATATTATTGAAACTGCTAATTGTCTTATACAAAATAACTTAATACGCTGTAAACAGGCTCCAGAAGAGCAAGTTCGTATTAACTCCGAACGCCAAGGATTAAGAGGAGAGGCAGTCTCCGCTTTAAAGTTCAATAATTTATCACGACAAGCAGGATGGATTAAAGACAAAATTCAATCTTGGGTCAACGTAGGGATTGCTCCTCATGAAATCGCTATTTTAGCTATTCGTTGGGATGATTTGAGTCCTATCCGCTTGCTTTTAGAAAGAGAAAGTATATCTACTTATGCCCTAAAAAATAATACTATTCCACTATTAAAAAACCGTTGCACTCGTTTACTAATTAATGCTTTACAGAAAGACTATAGCCTAGTTTTAAATCCTGAAGAATTAGTTCAGAAAAGATTTGAGGCGTTTTTTAAACGTACTGGTCGTAGCTTAACAGAACCTACTGTTAAAATCTTAATAAATATTGCTAGAGATTTAGATAAAGAACGAGGCTATGGGTTTGAAGATATTGTACTACCTATTAGCGTTGATGAAATATTGACTGCTATATTTGAGTTTAATGAAAATGGTGAATCCTTCCTAGAAGATAACTCAGTCTTAGTTACTAGCTGTCATGGTTCAAAAGGTTTGGAGTTCCGTAAAGTCATACTTTTAGGTGATGGATTTAAAACTAATTGTAATGAGATGGAATCAGAACGACGACTCTTTTATGTTGCTATGACTCGCGCCAAAGAAGAATTAATTGTTTGTTCTACTCAGCAGAATTTATTTGTACAGCAAGCTGGTTTAACTTCAGAGGTTATTGATTATAGTGAGACTCAACTTCCTCAGTTAATGCGTTACTTTGATTTAGCTCCAAGTAATGTTTATTTAGGATATGAAAACACTCAAAATAGACAAAATGTTATTAAAAAGTTATGTGAGGGTGATGTTATTGAGTTAAGAGGAAATAACCATAATAATGCTTGGAGAATTTTCACACCAAATAATAATGAAATTGGTCGTCTATCAAAGAGGGGAACACAACTTCTTAAGCATAAAGGTATTTTTCCTGGACAGTTCCAGTTTCAGCCTGGTGAAGTAACAGTCCGATATCTATATCACCATACTAAGAGAGATGACATAACAGGAAAAATTTCGGAGAATTGGTTTGTTGTGATTCCACAAATTCGAGTATGTAGAAATGCCAAGAAGAGTGATTTGAGATAGGCTAACTCCGCACAAAGAAGCTAATAAAACCCCCAAATATTACCGCATCCTAGACGGCATTTGTGACTTTGAACAGATGCCAAGGCTTACAAGGATTTATGCGAAAGACATGGTTGCCGTGATTGATTTAAACTCGCTTTAACCTAATAAAAGATAATCGTGAAAACTGAATTACCTCCATTAACTAATTGTGTTCTATTCTTTGTAGCTGTCATAAGTGTGGTGTATTTATATAGCAGCATAGCTCAAAGAAAATTAATTAAAAAGCAACGAAAAGTAGAAAGACCTAAATCTAGTTTTGGCTTTTTGATATTATGGAATCAAATTTTGTTAATTTCCTTTTTTTCTGTAACCTATATTATAGGATGGGATGCACCCTCAGTTGGTTTAAAACTTGAAATATTACCAGTATTTTCCTTAATGATTGGCTTGGGTTTCTATTGTATATTTGTGTTATTTTTAAATAAAATTCTAAATCTTTTGAGAGTCAGCCAAATTGTAGAAAATGATGCTTATCTCGTTACTTTAAGGCTTATGCCCCGACAAAAGCTTCAGAAAACATTATTTATTATTGCCGTATGTATATTAAATCCAATAACAGAAGAGTTGATATTTCGTGGAGTACTAGTACATCAATTAAGCCTATATACAAATAATTATTACTTGGCAATTTTTTTGGGATTGTTTGTAAGTGTTGGGAATCATATTTATCAAGGAAGACTGCATATTATTACGCATATTGTTTTTTATATTTTCACTGTAACATTGCTTTATTCAGATGTAGGACTTATTGGGTCTATAGGTTTTCACTTAGCAGGAGATATTTACCCGTTCATGTGGCTTAAATATCAGGTTAATAACTATAAACAACGAAGAAGGGAGGAACGCAGAGCTAAATATGTTTCCAATTAGAATATCAGACACAGTGAGTAAGAAAATTTGGAGATGGAGAAAGTAGCGACACCGGACAGCCCGTCGTAGACATCGCTCTCAAACTGGGGTAATCGCTCTAGTAAAATCAAAAACCACCCACATGATGTAAGTGGATATCAAAAGAGATTATGTATTTTTTATCAGTTACCAAACAGTTTATTAAGCACATCAGCTAGACGGTAGCCTGCCAAGCTCATCCGGCGTTCTGCTATTGGTTTGGCGGTAGCAGCATAATTTGGCGGTAACGGCTTTCCATCATTTTTATCCGTGCTGCCAGAAAGTTTGCCATTGAGATATGCTTTTTGTTTTGCTATCCTAAAACTCTCCAATTTTGCCCAATTATTAAATTGAGTTTCTCTTAACTCTGGCAATTTACTGCGTTGATAGTCGGCTCTTATCTTGGTTGCGGTGTTGCGAACAGTTTGAAAATTTTCTGAGCCAAGTATGAGGTCATCCCAGAATTTATGTAAACTAATTGTTTGACCATCTGGATTAACTCTAATATAAAAACGTGTACCACCTCTATCACCTTCTGGTTCTGGATACTCGTTAGTTATTAATTTGGTAGTATGCAATGGCTGATGCACATCTCCTACTAGATGGAATAGCCAGCATATTGCAACTGCTTTTTCGCTGTTGGTGGCATTACTTTGAATAATATCAAGATTTTTTTGAAAAGCAAATATAATATTTTCTTCACCGGGAATTTCACGAGGAATTGAATTTGAAGAACTGCCTGGTTGATAAGGAAAATTTATGTAGTGCCAAGTTGGGCGATCAAATGTTTGATTGCCACGAGCTTCATCTGGCCATTTTGCCGCCCACATAAATAAGTACAAATTTTTATTTTCAGCAGAAATATTAGATTGTTTGAGGGAATTCCACTGCTGCTCAAATTTAGAGTATTCAGGGTGTTCCTTCAAAATGGCAACCATTTTCTCAATTACTTCTTGATGATTCTGCGAGAGTTCCCTGTAAGCGATCGCTCCTGAAACCATGTGTCCAGCCTTATTCCAAGCAAAAGCTGGGTACTGCCAAACCAAGATTGTTGATAATACTGTCAATAAAGAAAACTTAGCGAAAGAATGTAACTTCAGCATAAAATTCTTTGTTAAAAAATACAGCTAAAGTATAGGTTGCATTCAGGTAAGTTAGGGTTAAATTTGCATGAAAAAAATAAATCACCCTACACAATACTCATATATTTCAATAAACAGAGCTGTACATTAACGAGTTTAAGGGTGTGATCGCATCTATTACCCTATGAATGAGTCATTTACCTCCAAGAATTTAGGTTCAGAACCACTTAAAAAATATTCCTGCTTAGAGTAAATAATTTTACATATTTTTCATTATTACGGATATGCACTGAGGTTTATTGCAATTCCGTATGACTAAAATGCAACAAACAATATAGCATTAGCTACTTAAGGTAGTGGGTCAAGCTTGCTCAATGACTATCAAAAAACCCTTGGCTTTCAAACAGCCACAGGTAGGGCATATCATTCGTGATTTGCGACTTTTGGCTGGGTTAACGCAAGAACAGTTTGCAGCCACTCTCGGCGTGACATATACCACGATTAATCGTTGGGAGAATGGACGCTCTAAACCGTCGCCGATGGCGAAGAAGCTTATTGAACAGAAGCTTAATGAGATGGGCGCTCAGGGTGAGGATTTGTTAACTAAATATTTGCCAAATTAGTTATTTACTCAGTTTCTGTGTGAGCGGTAAATATAGCTCTAATAGCCCACTTGTTCTAGTTTTTATATCCAACTGTTGATTGTAATTGTAAACATCAGGTGAGGCATCTAATGAACGGTAATACAAACATGAGAACTACTCAGCAAGTCACGGAAATTACAGGCGCTCCCGCCCAAGTTTGGGGAAACGTGTTAGTTCCAGCAAGAGGAACAATTCTTGTCAAAGTTACAGGTGATACTCTTGTTGGGACAACAAAAACTGGGTTAGAAAAGAGAGAGACTTGGATACGCATTCAAAATATTGATTCAGCAGAAACATTAGAAGCCCCTATTTATGCTTTATTGGGTTTTGGAGGATTCCTAGCTTTTTCATCTTTGGGTGCATTCAGCAACTCTTCTGTACTAGGTTTAATTTTACTTGTTGCAGCAGTCGCCCTAATTGTCTATGCAATAACTAATAAACGTCGATATCTAGCAATTCATAGTTATCGTACTTCAATTGTTGTTTTTATGAATAAGTCCCCAGAACTTTATCAGCAATTTGCTATGAATGTGCTGGCATTATCGCGCAAACTAAATACACCCAGTAATACACAAACAAGACAGCCTCAAACCCAAATTCAACCTTAGTTGATGAAGTCTATGTATATGAATCCCAGGATAAGAAATATAAATTTAAGCTCCACTAAAAGAAATTGCGATCGCTTCCAAATTCTTAGAGTAAATTTACAAAACATAAGGTAAGGAATATATGAATAAGTTTCCTTTTTTAGTATTTGAAGGATTAGATGGGGCTGGTAAAACTACTCTGGCAGAGCTATTTTCTAAGCGTCACAATTTTTCTTATTACAGCAGCATACCGCCTGAGTTAATTGCTTTACGAGAGCAAATAGCTGATACCCATTCTCCAATTACCACGTTTCATTTTTATACTTTGTGTAACCTTATGCGTAGCCATGAGTATGCATTAAAGTTGAATAATTCAGGCGTTGTGGCTGACAGATATGTGTTTTCTACTCTTGCTTACCACAGCCTGTTAATGAAACAAGACTTGTCTTGTCATTTCCGCATATTGCAATCAGAACAAAAATTTTTACTACCTGACGTTATTGTTTATGTGACAGCCTCTCAGCCTGTAATTTGCCAGCGTATTGCCAAGCGAAGTCAGGAAGTTCCTATGCAATGGTATGGGGATAAAGTTTCTGTTGAATACAACCTTATTGAATCATATAAGCGTATATTTTCACTAGTTGACATACCAATCTTGCAGATTGATACGACTAATTCTGATCCTGAGCAAGCTTATTCTACTTTGTGCTATGAACTGCACAGAATTGGTCAAAATATACCCATCATTCAGTCTACAGATTTTGCATTAACTAGCTAACTTCAACTTTTCAATTTACCAAAAAATATTATCATGCGACCAATATCTATAAATTTCCATCTGTGGAAACCATGCAATTATCATTGTCGATTTTGCTTTGCTACCTTTCGTGATGTCCCAGGATATTTAACTTTCAGTGATGCTAAACGCCTTCTTTCTTTATTGCGCGAGGCAGGTACAGAAAAAATTAACTTTGCTGGGGGAGAACCAACACTACACCCTTACATTGGTGAACTTGTAGCTGAGTCGCGTCGTTTGGGATTTGTAACAAGTATTGTGACCAATGGTGCGCGAATGACTGAATTGTTACACAAGCACGCTAGTGATATTGATTGGGTCGCATTGTCGGTAGATTCTGCTTCAGAAATGATTCAAAAACAGTTGGGGCGTGGGAATGGGGATCATGTACTACGATCAATTGCTTTGTTTGATAAATTACATCAATACGGTATTCATGTCAAACTTAATACAGTAGTCACCAGCCTTAACTTCCAAGAAGATATGTCAACCTTTGTAAGGCGGGTGCGTCCAGAAAGGTGGAAAGTCTTTCAAGTGCTGCCAGTGGAAGGTCAAAATGATGGGAGCGTCGAGGATCTGCTAATCTCGCCACACCAGTTTCAAGAATTTGTCGAACGACATCAAACCCTTTCAGATGAGGGAATAAGATTTGTCGCAGAGACAAACAACTTGATGAAAGATTCCTATGTAATGGTCAATCCACAAGGGCAGTTTTACAACAACACTACAACAGGGCGTTATTTGTATAGTTCACCAATTTTGGAAGCGGGTGTAAATGTTGCCCTGGCTCAAGTCGGTTGGAATGTAGAAACTTTTCTGGGTCGTGGAGGTATTTACTCTTGGAAATAGTTGCACCGCCAATTCCAGACTAAGGTTAGCGTACTTCCTCATTACTGATATTAGGGATACCCAAAAAAGCCAAGGAGTAAAAATCATGGGTCAATGGATTGATTTTCAACAAACTGTTAATCAAAGACTACTGAGAGAAGATTTAGATAAAGAACAAACTAAAGTCAGAAACATGAACACCAAAGGACACGCTCTTGTCCGGGGTATTGCTGGCTCTGGGAAATCTTTAGTTTTAAGAAATAGAGTTGAGAAAATAATTGATGATTTTGATAATATTTTAATCCTCAGCTATAACCGTTTTATGAGCGGATGGCTAAAATCGAAGCTAAGAGAGAAAGGTATTAGCAGGCAAGTAACTTGTAATACCTTTCAGAGTTGGGCTTATCGTAATTTAAACTATGATTATAAATTTGATAAAAATGATGAATTAAGAGCGCAAATTATAGATTTTGCGAAAAATTCAGACTTAAAATATCAAGCTATTTTAGTAGATGAAGCACAAGATTTCTATGATGAGTGGTTTCGTGCTTTGCTAGAAATTTTAGATGATGATACAAAATCTTTATTTTTTGTCTACGATAATACTCAATCAGTATATGGACAATCTCACAGAAGAAAGCAAGATTGGACATGGCGAAAGCTGGGAATTGATGTTGTGGGGCGTTCTCGGGAGCTATGCGGTTTCGTCAGATCCAGTAAAAAACAAGCGATCGCTAAATCATTTTCCCAGTAGTATAAATAAATTTATACTTTTTAAGCAGTATTAACACTTAAAAAGTCAAGATGAGTTTGAGTCATAACTTGCAAGACTCTCTTTTTTGAGCCAAAAAAAGCTAGGATTCCCTTTGAGCAAGAATTTAGAGATAGGGATTATCTACCTTAATGGAAAAAAATATATGTGCAACTTTAGATTTGAGTAAATCATTATCAGACTTTTCTTCGCAGGTAACAAAATATTTAGAATTGACGAACATCACGGAATGGAATGGGAAAATTCTTAAAGAAAGAGAAGAAAAAATTAGAGAAATTGCACTTATTTTAGCTGGACAGTGTATTGCAATTTTGTTGTATAACCTCTCCCAATCTCAGTCAGCTAATCAAACAGCTATGATTCAAACAAGAAGCTGGTGGGATACTACTATGCAAAAACATGGTTATAGAAAACGCCAAATCTTAACAGTTGGAAACGTTTTATTCACTCTAAAATTACCATATATGGTAATAAAAAACTCAACAAAGATCACAAATAAAATGTCTCTTCAGGGATTTTATCCCCTGTTAAAGTGGTTGGGGATGTCAGAAGGATTAACCCCGTTAGTATGGTCAACAGTTGCTCAATATGGTGCAATTACTAGCTCATTTGAAGCCGCCTGCACAACTTTAACTGGTTGGGGAATTGATCTTAGTTTAAAACGAATTGAGCGTTTGACATACAAATTTGGTCAAACTGGCATCAACTTACGGCAATCTAAAATATTAAATCGGCAGATGGGCATTTTACCTGAAGGTAATATTCTTAAAGACCAAAGAGTTGTTATAGCTGTAGATGGTGGTCGGAGTCGAATCCGAATTAATAAAAAGGGAAGAAAAAATTCCAAAACCAAGCGACACGGGTTTATCGGCAAATGGGTTGAGCCAAAGTTATTCACAATTTATATTGTTGATGAGCAAGGTAAAAAAATAAATACTTCTGAAATTCCTATTACGAATGATGGCACTTATGAAGGATATAAAGCGCTTTTGGAGATTTTAGAAGCGTATTTAGTTGGCTTGGGAATTAGTCAAGCAAAACAAGTCTTATTAATCGGGGATGGAGCGGAGTGGATCTGGATACATATCCCACCACTTTTGACAAGATTAGGATGCCCAGTCGAAACTTATCAGCTATTCGATTTCTATCATGTTACGGAAAATATAAAAGTATTTGCAGATGCTGCTTTTAATGAAGAAGCACAGTCTAAAGAATGGTTTGTAAAAGTTAGGAAGAGTTTAAAAAAAGGTAAAGCCAAATCTTTAATCAGCCAGATGGATGAGTTGATTGCTGTAGCTACCGGAGAGCGGTGTAAGATTATGGTAGTTAAGCGAAATTATATTTTAGATGCTTATCGTAAAGGGCGTTTAAATTACGATAAAGCAATAAATAAAAAACTACCTATTGGCAGTGGTGCAATTGAGAGTTTAATTCGCCAAGTTGTAAATTTAAGAATCAAGGGTAACAGTAAATTTTGGTTGAAAGAAAATGCAGAAATTATGTTACATCTGCGTTGTCAATGGATCGCCGGAAGTTGGGATAAGTTTTGTGGTTCTATTTTTAATTCCTTTATCAAACCAGAAACTGCTTGA

Protein sequences of DBSCAN-SWA_1

>NZ_CP046704|58875:113321|69179_69950_+|WP_114082169.1|DBSCAN-SWA
MPKPSNKSKSSLSKQEQQVKVNSNQWLTLTYQPVSLFSLKRSDATSMAARSNLVPTPYAIKMALLKVLLESQGRQHQSNFDQWIKSEFTWIRDLQIYIWPPEQLVVNRNGYKLRYYDQTADKADKSRTTLPMQGGFVFREWVHLQGHLQICCGGCDRLAELERLFAQINYFGKRGCFFQYLPEYKQETSEPLFQPNLITGFTAQLMDDLGEKATFNRINPFSTEKAQLDKDRVIKPGFLPLRLVATSARYDMYQRY
>NZ_CP046704|58875:113321|75214_76366_+|WP_114082174.1|DBSCAN-SWA
MPRAASSTSGKPKPKQKSVASVVTWADETELVGLVFELESTASALLYSQYTIGLHAWFLEQVRQFDPDLSAYLHDGESEKPFNISALSGQLIASGKQLRLEGNQIYYWYVNVLSQRVAKFLKHWLTQLPERLDLKGASLQIKQVSIAYAPTTYKQLLESSTDRPSSISLSFISPTSFRRKGNHFPLPVPENLFHSYLRRWNDFSSMPAEQESFLKWIDEGVIIHQHRLKSEKVAAGKRGSVTGFTGAISLGLTKAASANFEFSELFYALVRLAPYCGTGHKTTFGLGQTRLDWVEQETSKSIQLITNLLGERIEELIKLFTAQRKRTGGERTDKIAVTWATILARREMGESLKAIAEDLEMPISTVKTYVKLARKSLKQESNS
>NZ_CP046704|58875:113321|109475_110111_+|WP_114085915.1|DBSCAN-SWA
MNKFPFLVFEGLDGAGKTTLAELFSKRHNFSYYSSIPPELIALREQIADTHSPITTFHFYTLCNLMRSHEYALKLNNSGVVADRYVFSTLAYHSLLMKQDLSCHFRILQSEQKFLLPDVIVYVTASQPVICQRIAKRSQEVPMQWYGDKVSVEYNLIESYKRIFSLVDIPILQIDTTNSDPEQAYSTLCYELHRIGQNIPIIQSTDFALTS
>NZ_CP046704|58875:113321|92220_92727_+|WP_114082185.1|DBSCAN-SWA
MAKVTISIGLTDAEVKALSAMQISENESLNHTATRLLQGILGQSKTGLALSNGDEIKEIVKQEVNVLAASTPDGEEIKQVIRQELAQAIAQIKGLIDERNGGVALQTQEAVSVEQQVLPDYSAIRENILSKLKTGKQSAAKAIDAFIESLGAVKSEQQPATVELDVAS
>NZ_CP046704|58875:113321|98763_98967_-|WP_147262503.1|DBSCAN-SWA
MDYTLLEQCLGRAVWCRFIYPQVYRFTLISTPSPATMFCWLPSLKIIGSPLLPSVTTVVALGQNCDS
>NZ_CP046704|58875:113321|97998_98676_-|WP_114082192.1|DBSCAN-SWA
MDKNEKRILDSWQMNASLWAQAIRQQQIYSRAIATDAAILKAVSQLNPRTFLDIGCGEGWLSRQLFSLGIDGWGVDFCAALIDAARDSGDSRFVVCSYSDLASQRFSTISYFSCFICNFSIIGECALDEIAKAGHSLLESKGKIIIQTLHPIIACGDSTYSNAWRETSWQTVSDKPFHPTPWYFRTLESWINEFHALNYRLLNLYEPCDPKTNKPISIIFVFERE
>NZ_CP046704|58875:113321|100752_102372_+|WP_159402626.1|transposase|DBSCAN-SWA
MTASLNIRVQDIDHCGIVAGICDEMNLVEQINRLLGTHSQEIISAGQVVKAMILNGLGFVSAPLYLFEKFFVGKATEHLLGEGIRPEHLNDDRLGRVLDKLYEAGLTEVFVTVALCAARKFGVKMDSLHLDSSSFHVDGDYINNATAEDAEAGGIEITYGYSRDHRPDLKQFILDLMCSGDGDIPLYLRVADGNESDSAIFATIIADFKRQWQIDALFVADAALYTEENLQQMKHLRWVSRVPATLTAAKMLLEDMPEVAFNDSAMPGYRIAPSCSEYGGVRQSWLVVESQARKEADLKQLEKRLIKKLSVAQSELRQLSNQEFACSKDALIAAQRLSSKLPLHQLANIQVKEVKKHTGRGRPSKDAAPTFYYQVDATLEPKEIAIAIETKRAGRFILATNVLDAEELSDEDVLREYKAQQSTERGFRFLKDPLFFTSSVFLNSTERVAALAMIMGLCLLVYSLGQRALRQALERAKKTIDNQLGKPTSTPTLRWVFQCFMSIHLVTVSQIKQIANLTHERQWILQFFGAPCRKYYLLS
>NZ_CP046704|58875:113321|61861_63088_+|WP_114082196.1|transposase|DBSCAN-SWA
MQKAFKVTLIPTHNQEVLINKTIGCARYVYNRFLALRKELYNTEQKTLSYNACSQQLTVLKKENEWLKEVDKFALQNSLKNLETAYKNFFADLKKVKSKKVVGVPKFKKKHGCKQSYKTNLTNGNIQIIENRLKLPKLGWIKFHQSQDINGKLVNVTITRTSSGKYIASILCETEIEKHFQVTQNIGLDLGIKSYLVTSNGEVVDNPKYYRTQKRKLRKAHKKLSRTVKGSSNRAKAKIKLARTYERITNLRDDFLHKLSTRLIKENSIICIEDLRVANMVKNHKLALSLADASWTKFVTMLEYKALWHDRIVQKVGTFYPSSQTCNHCGFINPLVKDLKLREWSCPSCNSYNLRDKNAALNILSEGLRLLTAVGTPEVIKNACGELVSPEVIQAQIVEAGIKPLLVV
>NZ_CP046704|58875:113321|111860_113321_+|WP_114085918.1|transposase|DBSCAN-SWA
MEKNICATLDLSKSLSDFSSQVTKYLELTNITEWNGKILKEREEKIREIALILAGQCIAILLYNLSQSQSANQTAMIQTRSWWDTTMQKHGYRKRQILTVGNVLFTLKLPYMVIKNSTKITNKMSLQGFYPLLKWLGMSEGLTPLVWSTVAQYGAITSSFEAACTTLTGWGIDLSLKRIERLTYKFGQTGINLRQSKILNRQMGILPEGNILKDQRVVIAVDGGRSRIRINKKGRKNSKTKRHGFIGKWVEPKLFTIYIVDEQGKKINTSEIPITNDGTYEGYKALLEILEAYLVGLGISQAKQVLLIGDGAEWIWIHIPPLLTRLGCPVETYQLFDFYHVTENIKVFADAAFNEEAQSKEWFVKVRKSLKKGKAKSLISQMDELIAVATGERCKIMVVKRNYILDAYRKGRLNYDKAINKKLPIGSGAIESLIRQVVNLRIKGNSKFWLKENAEIMLHLRCQWIAGSWDKFCGSIFNSFIKPETA
>NZ_CP046704|58875:113321|69927_70953_+|WP_114082170.1|DBSCAN-SWA
MICTKDTEVTFAGLSIVLKQVETSISPTPLNSWLSETQLLPVWIPLRINGGVTKIMPVLPSSVLYSNLMQSICQQIAQNTLVEWWQKPYELTGVEVDSDALHVIQVSVTSAASLPALGRAIHAQCFQWFANADTALAEHLHQQNTLPLTAAMQYVSPQKMQLRITLLKKELLAPLLWGLSTNLGESIMLAGIPCQLGKWIDIVQVSSFEKLLQVTTQSVIELRFLSPTSFKQNRGVQSFPLPELVFNSLLRRWNIFAPPEQQFPEVEWNGLVSAYDLKTHALKMEGGAEIGAQGWVKYRFLDSQQARIATILAHFATFAGVGRKTAMGMGQVRLVESRLRG
>NZ_CP046704|58875:113321|110144_110978_+|WP_114085916.1|DBSCAN-SWA
MRPISINFHLWKPCNYHCRFCFATFRDVPGYLTFSDAKRLLSLLREAGTEKINFAGGEPTLHPYIGELVAESRRLGFVTSIVTNGARMTELLHKHASDIDWVALSVDSASEMIQKQLGRGNGDHVLRSIALFDKLHQYGIHVKLNTVVTSLNFQEDMSTFVRRVRPERWKVFQVLPVEGQNDGSVEDLLISPHQFQEFVERHQTLSDEGIRFVAETNNLMKDSYVMVNPQGQFYNNTTTGRYLYSSPILEAGVNVALAQVGWNVETFLGRGGIYSWK
>NZ_CP046704|58875:113321|82702_82918_-|WP_114082177.1|DBSCAN-SWA
MNNQPNHENLSPQETPCPICGSQNFVWGRTVGESVSQWVYFRADGAGWGEGEKLRARKCRDCNNVQLFSYD
>NZ_CP046704|58875:113321|71659_72637_+|WP_114082172.1|DBSCAN-SWA
MSVLYVTQADAVLSKNYEAFNVALKQSDGSWKKQTVAAQTVEQVVLMGNPQVTGDALVYALELGMPVHYLSSFGKYLGSALPGYSRNGQLRLAQYKLYSDPVGRLELVKAIVTAKIHNQYQVLYRHNERDNPLKERKSLVKSQKTIDQVRGIEGLAAREYFACWPRMVGKQWTFTGRNRRPPTDPVNSLLSFAYGLLRVQVTAAVHVAGLDPYIGYLHEVHHGQPAMVLDLMEEFRSLIADNVVLAVLHKHEIQPDDFNESLGAYRLKDSARKTFLQAFERKMNDEFKHPVFEYRCTYRRAIELQARLLGRHLQEGIPYKAFALR
>NZ_CP046704|58875:113321|108835_109354_+|WP_114085914.1|DBSCAN-SWA
MNGNTNMRTTQQVTEITGAPAQVWGNVLVPARGTILVKVTGDTLVGTTKTGLEKRETWIRIQNIDSAETLEAPIYALLGFGGFLAFSSLGAFSNSSVLGLILLVAAVALIVYAITNKRRYLAIHSYRTSIVVFMNKSPELYQQFAMNVLALSRKLNTPSNTQTRQPQTQIQP
>NZ_CP046704|58875:113321|86191_88087_+|WP_114082198.1|DBSCAN-SWA
MLLKKTLLVVFLLTLSTPNALAFSDTESYWAKHCIQQLKERKLITGYPDGSFRPETTVTRAQAAVLMLNAFPDSPVKRTAASFKDVPADYWANKAISTAYQKGFFSGYPGGIFQPNQPIPRAQIIGVVAAGKNYSPLPSPMQTLQQYFNDVGQIPNYAQNAIASATINSIVVNYPNVKQLKPLQSATRGEVAALMCRALNIYTVPPQYIAGVEVDSQEIRPLPGKLDLIPTFNSNSPELVTTEGILLSTFPPDGKQVHEAHLNYPFEGRFDIFAHHIVRAETPAQSLTVYQGIIVHNPGNEPVTVQVLQAASYLTKEAQFIALADMVENPQGTVYSGPGDRTMNDVLRGVRQEIFPEKLVIEPKETKILANLPIQVQAPSSNGRTTMMRLTSSSPVYIANLVKNSNISPTLGEWQELLDTGSLAGKRDPIPTPLDPPREPTVFSRVAGVSQGTQWKTQITDNSNVSELTIPSPGKAFSYPLGTVHLITLSTGQIQSAAMLKRYPDTAYFAHSNYGVEYNLTLPLRNITSETQTITVSIQTPVKDEGGTDRLLFLKPGVEQIFFRGTVRVRYIDDNGVEKTRYVHLVQRRGQRGEPLVTLKMLASEKRQVQIDFLYPPDSTPPQVLTVRTKR
>NZ_CP046704|58875:113321|107163_108123_-|WP_114085912.1|DBSCAN-SWA
MLKLHSFAKFSLLTVLSTILVWQYPAFAWNKAGHMVSGAIAYRELSQNHQEVIEKMVAILKEHPEYSKFEQQWNSLKQSNISAENKNLYLFMWAAKWPDEARGNQTFDRPTWHYINFPYQPGSSSNSIPREIPGEENIIFAFQKNLDIIQSNATNSEKAVAICWLFHLVGDVHQPLHTTKLITNEYPEPEGDRGGTRFYIRVNPDGQTISLHKFWDDLILGSENFQTVRNTATKIRADYQRSKLPELRETQFNNWAKLESFRIAKQKAYLNGKLSGSTDKNDGKPLPPNYAATAKPIAERRMSLAGYRLADVLNKLFGN
>NZ_CP046704|58875:113321|66408_68244_+|WP_114082167.1|DBSCAN-SWA
MTERLFITKKFGTYADTFLMLGLVQLVEYALKATNQKIDIQLVDEGTRYCIQLKKAVNLEPIGKLSYTNPFPPVKGKKTDISKISQETIIFDTVEQSDARKLYRDYVFQQRGKVQFHEDAPDPPHPSTQNGVVLTSMRHDRNHNELWQLGWQNKDDYGILLVTLFQAFSQENYSSLNGETKQVAELFKQATGRQLPSEASAVKVYLPTSVQGVNRIKADSNKVDSQKADWLTLWLIAGGLFSFGVAERVKIAERVYDWRVVALEPLDIQLSKYREVLDKLRKYNPPSGGYGIARFDAELVLRFCQQLLNSHPSQADAELDDFDLWQPINHFVSNFVGTHFGSKGQVYGVKEVFTLGLPGWIRPENSEELTDYLKVLNEHLFVIGSLSAEEGHSELLAAYRDFITGTNLRRFFRFQASYADYIVKRLADPKAKPPRLFSIAGLNTMTKKDTDFTKITTDPSFLRIAKAINQATVYAGKVKTQQGVIELDWQRTYGLAQRLSSQSGSKKDFLSEITDFLAKYQAENLRLSEQLLKEGKSLRRVWTTKEDLDRLVELVENYDTVLVANLLIAYGYARWTKAKEVDLEDENADINDEQDLNNLEPTENLGESNND
>NZ_CP046704|58875:113321|70980_71580_+|WP_114082171.1|DBSCAN-SWA
MNEDYLPLAYLNAWEYCPRRFYLEYVLGEMSDNEHIILGRHIHRNINEEGTLQEGEMLIHQQQWVWSDRLKVAGIIDAVEECDGQLVPVEYKKGKMAQHLNDHFQLCAAALCLEERTGRCLAYGEIFYHTNRRRQTVAFTPQLRQMTEQAIVLAQLASQTTMPVPIDNTKKCLSCSLKEICLPFEVKQLRVSMTSETED
>NZ_CP046704|58875:113321|96877_97981_+|WP_114082191.1|DBSCAN-SWA
MRIFVPGRLCLFGEHTDWAGEYRSVNPLIEKGYTLIVGTNQGIYANVLPNSTELIIRASLNDGRSYEPLRLAMESNTLKSVAKEGGFFSYAAGTAYQLLTHYGVGGLEVDNYLTDLPIQKGLSSSAAFCVLIARSFNRLYDLKMTIRSEMEFAYKGERTTPSLCGRMDQACAYGNRPILMIFDGQKIDLLELKVSHDLFFVIVDLGGSKNTQEILRRLNQCYPLATNSIEQNVQKYFGSISSEITQAAVEAIQLGDAQLLGALMTKAQAEFDRYVVPACPEQLTAKKLHLLLHHEPLKPYIFGGKGVGSQGDGTAQLIVKNQESQRKAIEIIKHDFPQMQALQLTISRLPTPMIDLAEDKNQYGDVY
>NZ_CP046704|58875:113321|90375_90684_+|WP_114082183.1|DBSCAN-SWA
MSQGVYPNNWKQIATALKADCDWRCTKCGKVCLRPGEKPPDWTKSQRKAHTLQVHHWNCDPGDNRLENLACLCSGCHLYYHRFGRGNISPGQLSLFAQKKVS
>NZ_CP046704|58875:113321|83160_83565_+|WP_159402625.1|DBSCAN-SWA
MQNILAIYKLSKTRIKGYMNRLKSLLLGGLLASVSIAALSTHANASVVNFRNEHLNTNTIAFNNAKLIRERQLHEQQAREQKARELRERQVREQKARELRERQAREQKARELRERQAREQKARELRERQARFHH
>NZ_CP046704|58875:113321|95098_95431_+|WP_114082189.1|DBSCAN-SWA
MFKGFSRPKKKSVLEDNELTTGIVQHPVTGLWQTWISFTGNDIQCITAHANPDDADRVAKQMASAWSEGKYKTGEEVTAFIQSLPTDAVIDPLPQNIVMQLSKQALSARK
>NZ_CP046704|58875:113321|108476_108725_+|WP_114085913.1|DBSCAN-SWA
MTIKKPLAFKQPQVGHIIRDLRLLAGLTQEQFAATLGVTYTTINRWENGRSKPSPMAKKLIEQKLNEMGAQGEDLLTKYLPN
>NZ_CP046704|58875:113321|88601_89060_+|WP_114082181.1|DBSCAN-SWA
MTVNDSTKKLVRQRAKFLCEYCHSSEEASAALFSIDHIIPQSLKGSDDPDNLALACQRCNGYRYNFTTGIDPDTGQMLPLFNPRQQKWSDHFIWSGDGLKIIGISSVGRATSNRLDLNDERHNEGSIVKARRLWLKGGWHPPDEDPRQVQEF
>NZ_CP046704|58875:113321|111063_111711_+|WP_114085917.1|DBSCAN-SWA
MGQWIDFQQTVNQRLLREDLDKEQTKVRNMNTKGHALVRGIAGSGKSLVLRNRVEKIIDDFDNILILSYNRFMSGWLKSKLREKGISRQVTCNTFQSWAYRNLNYDYKFDKNDELRAQIIDFAKNSDLKYQAILVDEAQDFYDEWFRALLEILDDDTKSLFFVYDNTQSVYGQSHRRKQDWTWRKLGIDVVGRSRELCGFVRSSKKQAIAKSFSQ
>NZ_CP046704|58875:113321|80205_80346_-|WP_159402624.1|DBSCAN-SWA
MLLFVGGGENATPNSPPQASLSQAGLWAGCDRSLSVSPSPIEENQR
>NZ_CP046704|58875:113321|92747_92936_-|WP_114082186.1|DBSCAN-SWA
MPSISYNRTDSQQPQSISIQGYVVRPGLHIVTYEQLKLLREQTQHHSQLEHLVSQGVIKLTG
>NZ_CP046704|58875:113321|93779_94265_+|WP_114082188.1|DBSCAN-SWA
MCAKGFGQPQPTKIDKLVESAVRYCHKRHPEALDQIFDNLPVKLNQEVVTGILAALQKDIDTLSWFCGYMASEINRSEDNQKPHHPIAELSKTLITSGMEPFTDFMPYPGCRLVILNSEKFESLPKSVQTIVQQAFDIRESSGTEAQTINDALLQELMVQE
>NZ_CP046704|58875:113321|83926_84388_-|WP_114082179.1|DBSCAN-SWA
MTVITPDRLVVEESPSHAAHEPNRTLWISEAGGLTLFGAFIEVLQPGSRSSIKHWHRAEDEMVYVLEGEITLIEGDTKTVLRPGDAATFQAGVAVGHFLENRSALATRCLVVGNRAAVDTITYPDLDRVCHRDRSLPDDIWTNSLGEPAPSPY
>NZ_CP046704|58875:113321|93310_93586_+|WP_114082187.1|DBSCAN-SWA
MNKGELVDAVAAKTNITKKQADEVISAFLSVVIEAVANGEKITLVGFGSFERRDRSEREGRNPKTNEPMTIPATKVPAFSAGKQFKEKVAP
>NZ_CP046704|58875:113321|81884_82586_+|WP_114082176.1|DBSCAN-SWA
MDKLLPEQLVKSIYQELLPRLQIESVNPRNPIQVSYLPQPWQLLGKGNYAAVVFHPDYPECVVKIYAPGRLGFEEEVEVYRRLGSHPAFSECLYAKDNFLILKRLYGTTLYDCMHLGLPIPQQVIRDIDKALDYARSRGLHPHDVHGRNVMMHQGRGLVVDISDFLHPEACSKWNHLKKAYYWLYRPVLRPLGLRVPYSALNMLRKSYRLATSFKISCCQLVLRLTRFKYLKL
>NZ_CP046704|58875:113321|89243_90203_+|WP_114082182.1|DBSCAN-SWA
MWLFRAKSQKLEETLSILAQIRQHSTSEEGIIILRQVLKSKYSIAVAQAAKIVGEFTITELVADLVEAFARMMVKPAQVDQNCLAKKEIAQTLYHLEYSDENLFLQGIRHIQMEPVWGGVEDTAAHLRGICALGLVRMNYSDVMNELADLLADPKPEARTAAAKAIAYTGNPQGVPLLRLKTRIGDQAPQVISECFSALLQLAPTDSLAIVASFLFDPKEQICELAALTLGESRLEEAFDLLRNCWGQTRNVELRRTLLLAIGMLRQDKAIDFLISLVAQGKDIDAKDAIAALGIYREDRELWQRVERASEQRANQLGL
>NZ_CP046704|58875:113321|63065_63281_-|WP_114082164.1|DBSCAN-SWA
MLLTEHRADRVVLYNISWQKFENLLVDLGESRSARVAYDDGTLEIMTPLPEHEYYKEIIGDILNLTPLKVA
>NZ_CP046704|58875:113321|64013_66059_+|WP_114082166.1|DBSCAN-SWA
MEIIQVEDADLQAIEGDRCRTFQAVSHPLNASVILDDIRAYQRKRVIIICNTVSQAQGLFRDLEELNYEGILHVTLLHSRFLPEHRAQKETDLKSIFAQSWQDDGNCYVLISTQVIEAGINITCQVMHTQLCPMNSLLQRAGRCARFGGEQGEVYIYPTVEVNAASCKIAIADLELEEESAPKKQSFLPYPQETCELTWSVLQEHTQSVQANENVGFRTEEQWINQVHTREDLLQQQRRLNNRMNFEQRFEDAFFRGDQSAGRELIRSIDSRSVFIWEEDGLIDIEEEVVDPQKLLSFSLPVSMLCKVWREFQNMEFGADWIFKQIENPKGKAETYSQPVCTPIKSREALIGSIRILVNPRYVHYDEHIGLLIGIDVFGNHFVSPDKSKRVIASEYRYNMDNYVGHLVLMWKCWREVFTVNRLKNGVSQETTFTSVRDELLAAGGRFIRGKIFPQTQEKEAEALFEMLVFLAIFTHDLGKLQVKWQEVMQGWQAIAHSSFSGRNPGKHLLAHTDYSPEDRHQRDALKDYEKKHKRPNHAVESAYLAQDILKQSLVPLLQDNFLADIEQIKYICHTVIMAAGRHHSAWAGGWDQAATAKIKSIELHPGAKQAIADSWRSIHRFLPQPLSLAKANLGKDVYPIKKDFDLNRFTPDQTEYLQLYLLIVRALRLCDQRSVQLHNI
>NZ_CP046704|58875:113321|68236_69199_+|WP_114082168.1|DBSCAN-SWA
MTNTHFPVHSISVSGTLSWQLHALNNEGNEGNQSLTRRYYIIQKDMTEPEYVNGVSGDMLKHIQAEHLHRIAIQEGLTLSEGGKQFHPDRIGYDLEKGLPVFTQSNTDLTAKTNQVLQLCTISDLEGFMVTVKGGQTLKRESVIEFGAAVGLPTLVKTQSYFHAKYGTDNPTPYNVQVNSGLYATVLNIEAFRIGYNPHNFSYSIDPIERKKRLDVLLKSVLYTYLQPNGAKRNTHLPHPDHFEGVITVSTRRCPAPMLSPLSASYSRQIHSLADTLNNLNGAGTIHCFDFETIAQFAEQIQTLIERSQPWESNNAEAIE
>NZ_CP046704|58875:113321|58875_59924_-|WP_114082162.1|transposase|DBSCAN-SWA
MSQDREEQIKACVRELAKLLYEEADKSQLTDLESIEKKVRSQILERVSPEIAPFFVEQKTGTKVGKTRKIKSLVGELTLKAKQLQRLGLKPRTRLSPLLKKCCLRLSANISYQNAEIEVEALTGVKVGHSTQQKLVLSQDFQLPLALQAVSEVSVDGGKVRLRGKPKAGCHWRDYKTVRLQGIYYGAFFDDNQSLIDYVNSQQLVDPLVCLGDGHDGVWNLVREFGQDQFSRCEILDWYHLKENLYKVGGSLKRLKAAETLLWKGQVEAAKTLFNYCRGKQAKNFIAYLEKHLPRIVNYSYYQAEQLCSIGSGAVESAIKQIGLRIKISGAQWNVESVNHILSERLSLS
>NZ_CP046704|58875:113321|78936_79926_+|WP_114082175.1|DBSCAN-SWA
MVTTPVYYLQFLDNPNIEISQDELRSLLGEIEVQLHRSRVYRRALAIVQKLIGEQTDQAQDLLKAVGREAIGLAFQRFAQQSQKVETVTDNKQATETVNSSPEIQQEHCALREEPSKNTAENSLWKKTLQLLNHQRISQAELAEQAELAAQQRMVCLRQIGQQLQKTRQSKGLSLDHIQLSTHIRTELIEALENGNWKELSDDIFVRGFIRRYGDALGLNGVALAASLPFLAAIPVTQPFSDQSKKGGGLEIRPTHLYIGYTALLAGAMGGLTLMSQQQANTNISIEQDNSSSAFQSLKQQSPTVKPGIKYTNTGVAVGSDIFPPEGLY
>NZ_CP046704|58875:113321|63406_64033_+|WP_114082165.1|DBSCAN-SWA
MISEYFQTLTTFPPRNFQREAIAKLLQRQDILLRAPTGSGKTETAIAPFLFAKALNIDFPNKLIYVVPLRTLANSLRQRAEILIANWEKVYPSSHFLAVTLQTGENPEDPRFEGDIVFCTIDQMLSSFLNIPYSVGRGSANVNSGAIFASYLVFDELHLLDPDRSFATVLKVLQQVKGISPFLLMTATLTNELATQIQTLVNNGNYSS
>NZ_CP046704|58875:113321|84987_86073_+|WP_114082197.1|DBSCAN-SWA
MTMKLPILFKTLTLLSFFLPIPFSMIANVPVIANTLNTPTNTEQPKRLKRTLSGHTAPVRALTLSPSGQVLASGSDDKTIKLWNATTGALLYTLTGHREGIKSIVFTPDEQTLISTSFDNTIKFWNTQTGKEVCTISEKTGVKAMLLTLDGQTLISGSGDNTIKFRNLKTRKIDRILKAETTALAITPDGKTLLSGGENGGRIRVWSLVTGKQIGSFTPPLPKKEDLISGSERASAPITLAVSKDGKMLLCGGYDDSFQSGGVRSTDGKGFKAWDLKTGKLVHDLSFGTSIDALIISPDSKTFIAGGLGREIILRDIKTGKSVMELTGHAGGIYGLAISSDGKILYSGSGDKSVKVWQIKV
>NZ_CP046704|58875:113321|95501_96518_-|WP_114082190.1|DBSCAN-SWA
MKVAIPTNTAEILKQVHQLESTVGLKNEACRSKFLIHPYFTSKVFLFLHGFTAGPYQFEPLGQAFFKKGHNVLIPLQPGHGRSGNWSRKNPPPLPTDIQIYQQFLLKWLQIAKTLGQQVVIGGLSTGGTLAAWLALEYPQEIDSTLLFTPYLASRYSLLDQLIKILPIYFEWFNKDASGNFGYKGFCLKSLRIFLQLAKEVSEKAQGCVSAPILMVCSEADRAVNLSKQQDFFRKVVKQQPKSWYYCFDDSLHIEHRMMTKLEDNDYEELVITLAKAFVESDLTWVEFEQIAKQITQGQTYDQIMLKLNFDGQVSQQLAAMMTQAFGCEHLNCIDPDS
>NZ_CP046704|58875:113321|94404_94971_-|WP_114082199.1|DBSCAN-SWA
MTLEPNQLNLFSDLTVTPARTAETLVMSLEALLKWKSQIFEYQHKVRENKPPQQTALFDLTPKHCDPDQIDPLLLRLVPMSFYRMPVDSPGSACVYFIIDSAASVILYVGEKCRSNKRWQGIHACKDYIASYQDLHYHYGLQTAVNAAFWWDAPVDRRTRQELELNLILKWRSPFNKDNWERWGQPFG
>NZ_CP046704|58875:113321|88365_88605_+|WP_114082180.1|DBSCAN-SWA
MITQMMVQPSFWVESGIKLSKVRDIHLFKFTEELQSRLEELSEKKKAGLLTTEEDAELAGILELDRIFTLLNAKIISES
>NZ_CP046704|58875:113321|60306_61635_+|WP_114082163.1|transposase|DBSCAN-SWA
MTFRLYPNKKTELILRYHRKLHKDLYNAAVNNRFNQYKIYNHKVDYFEQQNCLPAFKEIWIEYKELPSHALQATLKRVDFAFERWLKGLGKRPRFKSIRHYSGWTYPDCAGFKVESEGENGYLNLSKIGRIQMRGQAKYWGKPTTCTILYRNSKWYASITVNVLDQILKPEILSCGAVGIDLGCKSALSITDGENHQQIDAPKFLRSAEHLIKKASIDKRRKRAPNRKKKIKASRRFKKAQLKVSKLTRKVANQRQNWVHRVATEIVSSNSFVATEKLEVKNMTAKAKKGKRKKQKAGLNKSILDVGFGMLRSTIKYKVEQIGGVFIEVPTRRVLPSQTCPKCGNQHKKTLSLRVHECSCGYVQDRDIAAAEVMLYWAKGNLPGSGTGLADADVTSSTSRTRKQAGSMKQLGQMKRQKSQVKLAKNDFGNVETPSSGEASLG
>NZ_CP046704|58875:113321|72666_72960_+|WP_114082173.1|DBSCAN-SWA
MTTLFYLIIYDLPDNKAANKRRTRLHKMLSGYGKWTQYSVFECFLTAIQFATLQTKIEKLVKPEEDSVRLYILDAGAIKRTITYGSEIPRQEQTIVL
>NZ_CP046704|58875:113321|90821_91709_+|WP_114082184.1|DBSCAN-SWA
MNKGELVDAVAAEANVTKKQADKIQWSLTQRDVNLIELLMPIWSWFYRYYFQVKTDGWHHIPTEGKVLLVGSHNGGMASPDLVMMMYDWFSRFGTERLVYGLMHPYAWKVSPEIAQLAQKVGAIVAHPKMASAAFEMGASVLVYPGGQYDMFRPHSQRYKINFAENKGFVKLALKQEVPIIPVISVGAHDTLIVLCDCYAKVKQLHELGLPWLYQIDPGIFPIYLGLPWGLSIGPLPNIPLPVQIHTRVCRPITFERYGQDAAKDRNYVNACYELVHNQMQEELNQLVIDTQKSP
>NZ_CP046704|58875:113321|106249_107002_+|WP_114085911.1|protease|DBSCAN-SWA
MKTELPPLTNCVLFFVAVISVVYLYSSIAQRKLIKKQRKVERPKSSFGFLILWNQILLISFFSVTYIIGWDAPSVGLKLEILPVFSLMIGLGFYCIFVLFLNKILNLLRVSQIVENDAYLVTLRLMPRQKLQKTLFIIAVCILNPITEELIFRGVLVHQLSLYTNNYYLAIFLGLFVSVGNHIYQGRLHIITHIVFYIFTVTLLYSDVGLIGSIGFHLAGDIYPFMWLKYQVNNYKQRRREERRAKYVSN

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_114082162.1|58875_59924_-|transposase	ISKra4 family transposase	NA	NA	NA	NA
WP_114082163.1|60306_61635_+|transposase	transposase	A0A068A1P5	Thermus_phage	4.6e-35	31.2
WP_114082196.1|61861_63088_+|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A0H3UZC2	Geobacillus_virus	1.1e-104	52.1
WP_114082164.1|63065_63281_-	Uma2 family endonuclease	NA	NA	NA	NA
WP_114082165.1|63406_64033_+	DEAD/DEAH box helicase family protein	A0A2H4UVG1	Bodo_saltans_virus	3.6e-06	22.8
WP_114082166.1|64013_66059_+	CRISPR-associated helicase Cas3'	NA	NA	NA	NA
WP_114082167.1|66408_68244_+	hypothetical protein	NA	NA	NA	NA
WP_114082168.1|68236_69199_+	DevR family CRISPR-associated autoregulator	NA	NA	NA	NA
WP_114082169.1|69179_69950_+	hypothetical protein	NA	NA	NA	NA
WP_114082170.1|69927_70953_+	CRISPR system precrRNA processing endoribonuclease RAMP protein Cas6	NA	NA	NA	NA
WP_114082171.1|70980_71580_+	CRISPR-associated protein Cas4	NA	NA	NA	NA
WP_114082172.1|71659_72637_+	type I-D CRISPR-associated endonuclease Cas1	NA	NA	NA	NA
WP_114082173.1|72666_72960_+	CRISPR-associated endonuclease Cas2	NA	NA	NA	NA
WP_114082174.1|75214_76366_+	CRISPR-associated endoribonuclease Cas6	NA	NA	NA	NA
WP_114082175.1|78936_79926_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_159402624.1|80205_80346_-	hypothetical protein	NA	NA	NA	NA
WP_114082176.1|81884_82586_+	serine/threonine protein kinase	NA	NA	NA	NA
WP_114082177.1|82702_82918_-	hypothetical protein	NA	NA	NA	NA
WP_159402625.1|83160_83565_+	ATP-dependent DNA helicase	NA	NA	NA	NA
WP_114082179.1|83926_84388_-	cupin domain-containing protein	NA	NA	NA	NA
WP_114082197.1|84987_86073_+	WD40 repeat domain-containing protein	NA	NA	NA	NA
WP_114082198.1|86191_88087_+	DUF3370 family protein	NA	NA	NA	NA
WP_114082180.1|88365_88605_+	hypothetical protein	NA	NA	NA	NA
WP_114082181.1|88601_89060_+	HNH endonuclease	A0A1D8EUE9	Propionibacterium_phage	5.9e-06	31.8
WP_114082182.1|89243_90203_+	HEAT repeat domain-containing protein	NA	NA	NA	NA
WP_114082183.1|90375_90684_+	HNH endonuclease	NA	NA	NA	NA
WP_114082184.1|90821_91709_+	glycerol acyltransferase	NA	NA	NA	NA
WP_114082185.1|92220_92727_+	hypothetical protein	NA	NA	NA	NA
WP_114082186.1|92747_92936_-	hypothetical protein	NA	NA	NA	NA
WP_114082187.1|93310_93586_+	HU family DNA-binding protein	A0A2H4PAM3	Aphanizomenon_phage	1.4e-18	54.4
WP_114082188.1|93779_94265_+	hypothetical protein	NA	NA	NA	NA
WP_114082199.1|94404_94971_-	GIY-YIG nuclease family protein	NA	NA	NA	NA
WP_114082189.1|95098_95431_+	hypothetical protein	NA	NA	NA	NA
WP_114082190.1|95501_96518_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_114082191.1|96877_97981_+	GHMP kinase	NA	NA	NA	NA
WP_114082192.1|97998_98676_-	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_147262503.1|98763_98967_-	hypothetical protein	NA	NA	NA	NA
WP_159402626.1|100752_102372_+|transposase	IS1634 family transposase	NA	NA	NA	NA
WP_114085911.1|106249_107002_+|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_114085912.1|107163_108123_-	S1/P1 nuclease	NA	NA	NA	NA
WP_114085913.1|108476_108725_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_114085914.1|108835_109354_+	hypothetical protein	NA	NA	NA	NA
WP_114085915.1|109475_110111_+	deoxynucleoside kinase	NA	NA	NA	NA
WP_114085916.1|110144_110978_+	radical SAM protein	NA	NA	NA	NA
WP_114085917.1|111063_111711_+	AAA family ATPase	E3T5S4	Cafeteria_roenbergensis_virus	3.2e-05	27.6
WP_114085918.1|111860_113321_+|transposase	ISLre2 family transposase	NA	NA	NA	NA

3. NZ_CP046715

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP046715_1

• CRISPR_ID: NZ_CP046715_1
• CRISPR_location: 4126-4211
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP046715_1

Consensus_repeat	Method
TTTGCAATTAATGTGAGCCAAGTC	CRISPRCasFinder

spacers of NZ_CP046715_1

>1.1|4150|38|NZ_CP046715|CRISPRCasFinder
GGATGATTGCAAGCCCATTGCAAATAATAATGAGTCTG

CRISPR arrays and Neighbor proteins around NZ_CP046715_1

CRISPR arrays

The CRISPR arrays of NZ_CP046715_1

>merge|NZ_CP046715|1|4126-4211|CRISPRCasFinder
TTTGCAATTAATGTGAGCCAAGTCGGATGATTGCAAGCCCATTGCAAATAATAATGAGTCTGTTTGCAATTAATGTGAGCCGAAGT

>NZ_CP046715|1|1|4126-4211|CRISPRCasFinder
TTTGCAATTAATGTGAGCCAAGTC	GGATGATTGCAAGCCCATTGCAAATAATAATGAGTCTG
TTTGCAATTAATGTGAGCCGAAGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046715.1|WP_114081250.1|3214_4054_+|tyrosine-type-recombinase/integrase	unknown	unknown	gnl|CDD|274042
NZ_CP046715.1|WP_114085866.1|5820_6948_-|ATP-binding-protein	unknown	unknown	gnl|CDD|379114
NZ_CP046715.1|WP_114085864.1|4699_4954_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046715.1|WP_114085868.1|8140_8881_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NZ_CP046715.1|WP_114085870.1|11051_11966_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046715.1|WP_114085869.1|9905_10988_+|photosystem-II-q(b)-protein	unknown	unknown	gnl|CDD|130221
NZ_CP046715.1|WP_159402714.1|9306_9456_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046715.1|WP_114081249.1|320_1292_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|225806
NZ_CP046715.1|WP_114085865.1|5129_5819_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046715.1|WP_114085890.1|9027_9129_-|DUF1816-domain-containing-protein	unknown	unknown	gnl|CDD|370151
NZ_CP046715.1|WP_114085863.1|4275_4665_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046715.1|WP_114081251.1|1281_2928_-|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl|CDD|366234
NZ_CP046715.1|WP_114085867.1|7236_7839_-|tyrosine-type-recombinase/integrase	unknown	unknown	gnl|CDD|271197

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046715.1|WP_114081250.1|3214_4054_+|tyrosine-type-recombinase/integrase	gnl|CDD|274042	TIGR02224, Tyrosine_recombinase_XerC, tyrosine recombinase XerC. The phage integrase family describes a number of recombinases with tyrosine active sites that transiently bind covalently to DNA. Many are associated with mobile DNA elements, including phage, transposons, and phase variation loci. This model represents XerC, one of two closely related chromosomal proteins along with XerD (TIGR02225). XerC and XerD are site-specific recombinases which help resolve chromosome dimers to monomers for cell division after DNA replication. In species with a large chromosome and homologs of XerC on other replicons, the chomosomal copy was preferred for building this model. This model does not detect all XerC, as some apparent XerC examples score in the gray zone between trusted (450) and noise (410) cutoffs, along with some XerD examples. XerC and XerD interact with cell division protein FtsK. [DNA metabolism, DNA replication, recombination, and repair].	5.07702e-21
NZ_CP046715.1|WP_114081249.1|320_1292_-|AAA-family-ATPase	gnl|CDD|225806	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion].	2.06497e-48
NZ_CP046715.1|WP_114085866.1|5820_6948_-|ATP-binding-protein	gnl|CDD|379114	pfam13304, AAA_21, AAA domain, putative AbiEii toxin, Type IV TA system. Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.	1.12455e-10
NZ_CP046715.1|WP_114085890.1|9027_9129_-|DUF1816-domain-containing-protein	gnl|CDD|370151	pfam08846, DUF1816, Domain of unknown function (DUF1816). Crocosphaera watsonii CpcD is associated with the pfam01383 domain suggesting this presumed domain could have a role in phycobilisomes.	3.83154e-08
NZ_CP046715.1|WP_114085869.1|9905_10988_+|photosystem-II-q(b)-protein	gnl|CDD|130221	TIGR01151, Photosystem_QB_protein, photosystem II, DI subunit (also called Q(B)). This model describes the Photosystem II, DI subunit (also called Q(B)) in bacterial and its equivalents in chloroplast of algae and higher plants. Photosystem II is many ways functionally equivalent to bacterial reaction center. At the core of Photosystem II are several light harvesting cofactors including plastoquinones, pheophytins, phyloquinones etc. These cofactors are intimately associated with the polypeptides, which principally including subunits DI, DII, Cyt.b, Cyt.f and iron-sulphur protein. Together they participate in the electron transfer reactions that lead to the net production of the reducting equivalents in the form of NADPH, which are used for reduction of CO2 to carbohydrates(C6H1206). Phosystem II operates during oxygenic photosynthesis and principal electron donor is H2O. Although no structural data is presently available, a huge body of literature exits that describes function using a variety of biochemical and biophysical techniques. [Energy metabolism, Electron transport, Energy metabolism, Photosynthesis].	0
NZ_CP046715.1|WP_114085868.1|8140_8881_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	6.08042e-24
NZ_CP046715.1|WP_114081251.1|1281_2928_-|DDE-type-integrase/transposase/recombinase	gnl|CDD|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	1.79386e-07
NZ_CP046715.1|WP_114085867.1|7236_7839_-|tyrosine-type-recombinase/integrase	gnl|CDD|271197	cd01197, INT_FimBE_like, FimB and FimE and related proteins, integrase/recombinases. This CD includes proteins similar to E.coli FimE and FimB and Proteus mirabilis MrpI. FimB and FimE are the regulatory proteins during expression of type 1 fimbriae in Escherichia coli. The fimB and fimE proteins direct the phase switch into the 'on' and 'off' position. MrpI is the regulatory protein of proteus mirabilis fimbriae expression. This family belongs to the integrase/recombinase superfamily.	1.19247e-50

Protein sequences

>NZ_CP046715.1|WP_114081250.1|3214_4054_+|tyrosine-type-recombinase/integrase
MRIIRQLLLWIVEHPGSGGDFQPEQLTKTAMEIYLAYLDTSGYSIAHQARVKSAVSGFARWLIEEKGILRRNPTRGLNIPAQPLLAPRQLTPDQRYILRNLIEKDGHPRSMAVFALGYWAGCRVSDVSWLRIEHTHIGPKVGWLHVGYKGGKARDIDLINAVRKPMYEYIHHGGRDTESDYTFTSQRNERLTEAGIHRWWKNIKAQATVSEWELIHDVTFHDLRHDFAHRAREAGWTLEEVAYYLGHITKKGTPAIQTTVRYTQSSRQQVKDKLALLKG
>NZ_CP046715.1|WP_114081251.1|1281_2928_-|DDE-type-integrase/transposase/recombinase
MPAEALTNLRHRLDMLPSRCQERRQLMEETASLYGVSIDTLYRALRNSSRPKSINRSDSGTPRKLSQAEMELYCEVIAATKIRTCNKKGRHVSTARAIELLEDFGMNTPQGFIKPPKGLLTKATVNRYLKTWGYDHLTMTRQPPAVRFQATHSNECWHFDLSPSDLKHVKQPLWVETGKGNPLLMLYSVVDDRSGVCYQEYHCVYGEDVTAALRFLFNAMTASTSDGCPFQGIPEMIYTDNGPIAKSHVFQNVMDCLGIKLASHLPAGKDGRRVTARSKGKVERPFRTVKEAHETLYHFHEPENEVEANLWLRQYLLNYNDQKHRTEAHSRLEDWLRNLPKSGIRQMCSWERFCTFAREPQRRKVDATARVSVEGVAYEVNPDLAGETVVLWWGLFDNELYVEKGDQRYGPFYPVDGPIPLHRYRKHKKTKTEERADRIADLALKLGLPRTALDKNADLQFLVDKYKEIEPTVTPFKDPDPFQEFTYPTVLFAKLAISDYLAKPLAKLSTEQIAFIDGLLAETLNKKVIIERVRQYFHSNKGGQQNAH
>NZ_CP046715.1|WP_114081249.1|320_1292_-|AAA-family-ATPase
MLTEVMEHFRLVKEFPKAGYYETDHQKQMFKDIKAAIHSGKLIAITGIIGCGKTTTLRRLFDVLEKEGKILVSKSLSVDKERATLPTLIAALFYDLSTDKEIKIPKDGEKRERELRDLIRKGKKSVALFVDEAHDLHYSTLTGLKRLIEVVEDGGGTLSVVLAGHPKLKNDLRRPTMEEIGYRATVFSLEGIVGNQREYIEWLVSECTISDTPIGEILEAEAIELLATRLLTPLQIEQHLTLALEAAYRVAVKPVTTVIVESVLSKQIDDLEPTLTRHGYDVRGLAEQFNAKPAEIKSLFRGQLDPTRARELQEQMLAAGLPL
>NZ_CP046715.1|WP_114085863.1|4275_4665_+|hypothetical-protein
MRAATLNELRQKIKQSSQPIDFFRDNPPPQWNRIIWKNQVLLLPLAFTTEEINQIYKLYNEFDDIIKKYSILRELISEYNDIPEKIQMSIEDTFLLDNKIQLSAKIRTKLIEFYNTIGEILDRYKNPIV
>NZ_CP046715.1|WP_114085864.1|4699_4954_+|hypothetical-protein
MSNSANVAQVFSTFVNLTKELKPFVKTDDLRIAFDSEGQVYLIGDDFQEQIHANFSLWRKVRNEIRILIAKHRSQYKPDEKTNP
>NZ_CP046715.1|WP_114085865.1|5129_5819_-|hypothetical-protein
MNIYFLVEGKSTERKVYPAWLAYLLPELKRVDDYCEVVKNNYYLFSADGYPSIIHHHLPNAIIDIQENGNYNYLVVCLDADEVSYDYRKQEVIDYLKFQNINLGNIQLIVIIQNRCFETWFLGNRKIYSRQPQSTPLLDYIHYYDISANCPELMGKYYNFNTHAQFHENYLKELFKAKKIIYSKNKPGEVVKQYYLEQLLLRIEDKKNDLLSFQDFINFCILIKSKLLI
>NZ_CP046715.1|WP_114085866.1|5820_6948_-|ATP-binding-protein
MKINQITYYDFQRKWNFETIDFSNLTLLVGISGVGKTQILKSIVNIQSIAQGKSLNGVKWDIHFTTENGLEYHWTGEFESKTNVSLIVDDNENEKSEFKINNESLSINGKNIIERDNNQIIFNDQVLPKLSPFQSAIAILSEEEDISPVYKGFNKIIYNDQSNSINEIHIIRYAPLAKKYSSSSLDSLKESDLPTQIKLALVSNYFPEIFNQIKEHFVDIFLQVEDIKLAPNEYAELPIVLAEYPFVQLKEKGVNNWISQNRISSGMFRTLMHISELYLSAEGTVILIDEFENSLGVNCIDVLTDLLLINKKMQFIITSHHPYIINRIGIDNWKIVTRRGGVVKAKDSQYFNLGKSKHEAFMQLINLDAYKEGVE
>NZ_CP046715.1|WP_114085867.1|7236_7839_-|tyrosine-type-recombinase/integrase
MRPPPPIRLPNKYYRSREYLTPSEVRSLLDAALERKARYSHRDYTLMLLMFRHGLRVGEAVGAKCGLRWDAVMWGERQIFITREKGSDSGVHPLRDDELELLKQLREMLPDSKYIFVSERGEVMSTDAVRKLLGRLAATAGLDIKVHCHMMRHACGYYLVNQGYNTREIQDFLGHRDIKHTEKYTKLNARRFLNFDWGDL
>NZ_CP046715.1|WP_114085868.1|8140_8881_-|class-I-SAM-dependent-methyltransferase
MVANIFDGNSVFEEDYLYFYETLLTLERTQHEVDLICRLLDLQAGMSILDLACGHGRIANQLGARGYHVTGLDATAFFLEKANQDAASNGVKVEYLQGDMRSLPFSERFNCIINCFTAFGYFDDNENRAVLTQAYRALKVGGKLLIDIQNFSRVLQEFTPELITEREGNYMLARTHYDALTNRTHTERIIIRDGQVRRGQYFVRNFTFPEIRDWLLQTGFSEVEGYGYDGEPFALDSRRMIVVASK
>NZ_CP046715.1|WP_114085890.1|9027_9129_-|DUF1816-domain-containing-protein
MYYFGPFQSFVEAKAACPGYVDDHNCCNNSKIF
>NZ_CP046715.1|WP_159402714.1|9306_9456_-|hypothetical-protein
MIRGKVTEAVTRGKRACNYYATNVSVFMMIEDSDRLPLLKSSDLNWSRN
>NZ_CP046715.1|WP_114085869.1|9905_10988_+|photosystem-II-q(b)-protein
MTATLQQRSSANVWDQFCEWITSTNNRIYIGWFGVVMIPTLLAATACFVIAFIAAPPVDIDGIREPVAGSLIYGNNIISGAVVPSSNAIGLHFYPIWEAASLDEWLYNGGPYQLVIFHFLIGVFCYLGREWELSYRLGMRPWIAIAYSAPVAAATAVFLVYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHQLGVAGVFGGSLFSAMHGSLVTSSLVRETTETESQNYGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVIGIWFTALGVSTMAFNLNGFNFNQSIIDSEGRVIATWADVINRANLGMEVMHERNAHNFPLDLAAGDLAPVALTAPAING
>NZ_CP046715.1|WP_114085870.1|11051_11966_-|hypothetical-protein
MASAEFTSPESTQAVPTVENPSDGEQVNVDTSTEIEIESPAAIFQAVGVITGSVNFTTDGQSTVTIGSYEYPLYYSKRQWCVLNALKKEIENTGNHNQRLVVYPKAIHFPRREQPHRIAFQLVGFDRGRKLDAVSGELEDLEFKLSGLWQFIPVCSTPCISVFRNFSDERLEFIKQSEPARKVKFMKASHIPLLWKDAPVRPFRFNPKVAKEEQGRAAFVTVKAKFLPGRDVFGFVALTALPKDSAPRYLKASKEDKATVQLAAQKAKPRVQRPSKKHNLGSSNPPLKPILKKKPPLVEGEADK

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP046715_1	1.1|4150|38|NZ_CP046715|CRISPRCasFinder	4150-4187	38	NZ_CP046708.1	45893-45930	0	1.0
NZ_CP046715_1	1.1|4150|38|NZ_CP046715|CRISPRCasFinder	4150-4187	38	NZ_CP046705.1	76103-76140	0	1.0
NZ_CP046715_1	1.1|4150|38|NZ_CP046715|CRISPRCasFinder	4150-4187	38	NZ_CP046708.1	49872-49909	1	0.974
NZ_CP046715_1	1.1|4150|38|NZ_CP046715|CRISPRCasFinder	4150-4187	38	NZ_CP046705.1	214667-214704	1	0.974
NZ_CP046715_1	1.1|4150|38|NZ_CP046715|CRISPRCasFinder	4150-4187	38	NZ_CP046705.1	80082-80119	1	0.974
NZ_CP046715_1	1.1|4150|38|NZ_CP046715|CRISPRCasFinder	4150-4187	38	NZ_CP046715.1	171-208	1	0.974
NZ_CP046715_1	1.1|4150|38|NZ_CP046715|CRISPRCasFinder	4150-4187	38	NZ_CP046710.1	35911-35948	1	0.974
NZ_CP046715_1	1.1|4150|38|NZ_CP046715|CRISPRCasFinder	4150-4187	38	NZ_CP046709.1	37614-37651	1	0.974

1. spacer 1.1|4150|38|NZ_CP046715|CRISPRCasFinder matches to position: 45893-45930, mismatch: 0, identity: 1.0

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccattgcaaataataatgagtctg	Protospacer
**************************************

2. spacer 1.1|4150|38|NZ_CP046715|CRISPRCasFinder matches to position: 76103-76140, mismatch: 0, identity: 1.0

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccattgcaaataataatgagtctg	Protospacer
**************************************

3. spacer 1.1|4150|38|NZ_CP046715|CRISPRCasFinder matches to position: 49872-49909, mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

4. spacer 1.1|4150|38|NZ_CP046715|CRISPRCasFinder matches to position: 214667-214704, mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

5. spacer 1.1|4150|38|NZ_CP046715|CRISPRCasFinder matches to position: 80082-80119, mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

6. spacer 1.1|4150|38|NZ_CP046715|CRISPRCasFinder matches to position: 171-208, mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

7. spacer 1.1|4150|38|NZ_CP046715|CRISPRCasFinder matches to position: 35911-35948, mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

8. spacer 1.1|4150|38|NZ_CP046715|CRISPRCasFinder matches to position: 37614-37651, mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP046715_1	1.1|4150|38|NZ_CP046715|CRISPRCasFinder	4150-4187	38	NZ_CP046705	Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence	76103-76140	0	1.0
NZ_CP046715_1	1.1|4150|38|NZ_CP046715|CRISPRCasFinder	4150-4187	38	NZ_CP046705	Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence	218646-218683	0	1.0
NZ_CP046715_1	1.1|4150|38|NZ_CP046715|CRISPRCasFinder	4150-4187	38	NZ_CP046708	Nostoc sp. ATCC 53789 plasmid pNsp_e, complete sequence	45893-45930	0	1.0
NZ_CP046715_1	1.1|4150|38|NZ_CP046715|CRISPRCasFinder	4150-4187	38	NZ_CP046709	Nostoc sp. ATCC 53789 plasmid pNsp_f, complete sequence	41593-41630	0	1.0
NZ_CP046715_1	1.1|4150|38|NZ_CP046715|CRISPRCasFinder	4150-4187	38	NZ_CP046710	Nostoc sp. ATCC 53789 plasmid pNsp_g, complete sequence	39890-39927	0	1.0
NZ_CP046715_1	1.1|4150|38|NZ_CP046715|CRISPRCasFinder	4150-4187	38	NZ_CP046715	Nostoc sp. ATCC 53789 plasmid pNsp_l, complete sequence	4150-4187	0	1.0
NZ_CP046715_1	1.1|4150|38|NZ_CP046715|CRISPRCasFinder	4150-4187	38	NZ_CP046705	Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence	214667-214704	1	0.974
NZ_CP046715_1	1.1|4150|38|NZ_CP046715|CRISPRCasFinder	4150-4187	38	NZ_CP046705	Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence	80082-80119	1	0.974
NZ_CP046715_1	1.1|4150|38|NZ_CP046715|CRISPRCasFinder	4150-4187	38	NZ_CP046708	Nostoc sp. ATCC 53789 plasmid pNsp_e, complete sequence	49872-49909	1	0.974
NZ_CP046715_1	1.1|4150|38|NZ_CP046715|CRISPRCasFinder	4150-4187	38	NZ_CP046709	Nostoc sp. ATCC 53789 plasmid pNsp_f, complete sequence	37614-37651	1	0.974
NZ_CP046715_1	1.1|4150|38|NZ_CP046715|CRISPRCasFinder	4150-4187	38	NZ_CP046710	Nostoc sp. ATCC 53789 plasmid pNsp_g, complete sequence	35911-35948	1	0.974
NZ_CP046715_1	1.1|4150|38|NZ_CP046715|CRISPRCasFinder	4150-4187	38	NZ_CP046715	Nostoc sp. ATCC 53789 plasmid pNsp_l, complete sequence	171-208	1	0.974
NZ_CP046715_1	1.1|4150|38|NZ_CP046715|CRISPRCasFinder	4150-4187	38	AP018278	Calothrix sp. NIES-4101 plasmid plasmid5 DNA, complete genome	21799-21836	3	0.921

1. spacer 1.1|4150|38|NZ_CP046715|CRISPRCasFinder matches to NZ_CP046705 (Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence) position: , mismatch: 0, identity: 1.0

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccattgcaaataataatgagtctg	Protospacer
**************************************

2. spacer 1.1|4150|38|NZ_CP046715|CRISPRCasFinder matches to NZ_CP046705 (Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence) position: , mismatch: 0, identity: 1.0

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccattgcaaataataatgagtctg	Protospacer
**************************************

3. spacer 1.1|4150|38|NZ_CP046715|CRISPRCasFinder matches to NZ_CP046708 (Nostoc sp. ATCC 53789 plasmid pNsp_e, complete sequence) position: , mismatch: 0, identity: 1.0

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccattgcaaataataatgagtctg	Protospacer
**************************************

4. spacer 1.1|4150|38|NZ_CP046715|CRISPRCasFinder matches to NZ_CP046709 (Nostoc sp. ATCC 53789 plasmid pNsp_f, complete sequence) position: , mismatch: 0, identity: 1.0

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccattgcaaataataatgagtctg	Protospacer
**************************************

5. spacer 1.1|4150|38|NZ_CP046715|CRISPRCasFinder matches to NZ_CP046710 (Nostoc sp. ATCC 53789 plasmid pNsp_g, complete sequence) position: , mismatch: 0, identity: 1.0

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccattgcaaataataatgagtctg	Protospacer
**************************************

6. spacer 1.1|4150|38|NZ_CP046715|CRISPRCasFinder matches to NZ_CP046715 (Nostoc sp. ATCC 53789 plasmid pNsp_l, complete sequence) position: , mismatch: 0, identity: 1.0

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccattgcaaataataatgagtctg	Protospacer
**************************************

7. spacer 1.1|4150|38|NZ_CP046715|CRISPRCasFinder matches to NZ_CP046705 (Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence) position: , mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

8. spacer 1.1|4150|38|NZ_CP046715|CRISPRCasFinder matches to NZ_CP046705 (Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence) position: , mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

9. spacer 1.1|4150|38|NZ_CP046715|CRISPRCasFinder matches to NZ_CP046708 (Nostoc sp. ATCC 53789 plasmid pNsp_e, complete sequence) position: , mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

10. spacer 1.1|4150|38|NZ_CP046715|CRISPRCasFinder matches to NZ_CP046709 (Nostoc sp. ATCC 53789 plasmid pNsp_f, complete sequence) position: , mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

11. spacer 1.1|4150|38|NZ_CP046715|CRISPRCasFinder matches to NZ_CP046710 (Nostoc sp. ATCC 53789 plasmid pNsp_g, complete sequence) position: , mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

12. spacer 1.1|4150|38|NZ_CP046715|CRISPRCasFinder matches to NZ_CP046715 (Nostoc sp. ATCC 53789 plasmid pNsp_l, complete sequence) position: , mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

13. spacer 1.1|4150|38|NZ_CP046715|CRISPRCasFinder matches to AP018278 (Calothrix sp. NIES-4101 plasmid plasmid5 DNA, complete genome) position: , mismatch: 3, identity: 0.921

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
tgacgattgcaagcccgttgcaaataataatgagtctg	Protospacer
 **.************.*********************

4. NZ_CP046706

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP046706_1

• CRISPR_ID: NZ_CP046706_1
• CRISPR_location: 125124-125215
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP046706_1

Consensus_repeat	Method
CATGGGGGCTATATGGGGGCTGT	CRISPRCasFinder

spacers of NZ_CP046706_1

>1.1|125147|46|NZ_CP046706|CRISPRCasFinder
GTGTACCCCAAGATTATTTAGAGGCTTGAGCAAAATTTGACTCCCA

CRISPR arrays and Neighbor proteins around NZ_CP046706_1

CRISPR arrays

The CRISPR arrays of NZ_CP046706_1

>merge|NZ_CP046706|1|125124-125215|CRISPRCasFinder
CATGGGGGCTATATGGGGGCTGTGTGTACCCCAAGATTATTTAGAGGCTTGAGCAAAATTTGACTCCCACATGGGGGCTATATGGGGGCTAT

>NZ_CP046706|1|1|125124-125215|CRISPRCasFinder
CATGGGGGCTATATGGGGGCTGT	GTGTACCCCAAGATTATTTAGAGGCTTGAGCAAAATTTGACTCCCA
CATGGGGGCTATATGGGGGCTAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046706.1|WP_114083970.1|124118_124409_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046706.1|WP_114083938.1|133979_134381_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046706.1|WP_159402673.1|117892_118843_-|RNA-polymerase-sigma-factor,-RpoD/SigA-family	unknown	unknown	gnl|CDD|274382
NZ_CP046706.1|WP_159402634.1|113353_114859_+|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|223737
NZ_CP046706.1|WP_114083940.1|135748_136129_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046706.1|WP_114083935.1|127684_128026_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046706.1|WP_159402675.1|126772_127456_-|hypothetical-protein	unknown	unknown	gnl|CDD|173502
NZ_CP046706.1|WP_109012796.1|116570_117158_+|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|368559
NZ_CP046706.1|WP_114081261.1|114887_116123_-|AIPR-family-protein	unknown	unknown	gnl|CDD|378452
NZ_CP046706.1|WP_114083937.1|133180_133684_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046706.1|WP_114083932.1|125386_126346_+|ParM/StbA-family-protein	unknown	unknown	gnl|CDD|212669
NZ_CP046706.1|WP_114083931.1|124458_124974_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046706.1|WP_114083939.1|134488_135043_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046706.1|WP_114083933.1|126351_126642_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046706.1|WP_114081260.1|117548_117800_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046706.1|WP_159402674.1|118934_121181_-|ATP-dependent-RecD-like-DNA-helicase	unknown	unknown	gnl|CDD|273632
NZ_CP046706.1|WP_104899617.1|122609_123437_-|ParA-family-protein	unknown	unknown	gnl|CDD|224113
NZ_CP046706.1|WP_114083936.1|128315_133106_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046706.1|WP_147262544.1|134925_135738_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046706.1|WP_114083930.1|121437_122610_-|ParB/RepB/Spo0J-family-partition-protein	unknown	unknown	gnl|CDD|319251

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046706.1|WP_159402673.1|117892_118843_-|RNA-polymerase-sigma-factor,-RpoD/SigA-family	gnl|CDD|274382	TIGR02997, RNA_polymerase_sigma_subunit_sigma70/sigma32, RNA polymerase sigma factor, cyanobacterial RpoD-like family. This family includes a number of closely related sigma-70 (TIGR02937) factors in the cyanobacteria. All appear most closely related to the essential sigma-70 factor RpoD, and some score above trusted to the RpoD C-terminal domain model (TIGR02393).	2.67332e-151
NZ_CP046706.1|WP_159402634.1|113353_114859_+|FAD-dependent-oxidoreductase	gnl|CDD|223737	COG0665, DadA, Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism].	2.84657e-41
NZ_CP046706.1|WP_159402675.1|126772_127456_-|hypothetical-protein	gnl|CDD|173502	PTZ00266, PTZ00266, NIMA-related protein kinase; Provisional.	2.54214e-08
NZ_CP046706.1|WP_114081261.1|114887_116123_-|AIPR-family-protein	gnl|CDD|378452	pfam10592, AIPR, AIPR protein. This family of proteins was identified in as an abortive infection phage resistance protein often found in restriction modification system operons.	2.66475e-40
NZ_CP046706.1|WP_159402674.1|118934_121181_-|ATP-dependent-RecD-like-DNA-helicase	gnl|CDD|273632	TIGR01448, recD_rel, helicase, putative, RecD/TraA family. This model describes a family similar to RecD, the exodeoxyribonuclease V alpha chain of TIGR01447. Members of this family, however, are not found in a context of RecB and RecC and are longer by about 200 amino acids at the amino end. Chlamydia muridarum has both a member of this family and a RecD. [Unknown function, Enzymes of unknown specificity].	0
NZ_CP046706.1|WP_104899617.1|122609_123437_-|ParA-family-protein	gnl|CDD|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	2.421e-24
NZ_CP046706.1|WP_109012796.1|116570_117158_+|Uma2-family-endonuclease	gnl|CDD|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	4.55914e-30
NZ_CP046706.1|WP_114083932.1|125386_126346_+|ParM/StbA-family-protein	gnl|CDD|212669	cd10227, ParM_like, Plasmid segregation protein ParM and similar proteins. ParM is a plasmid-encoded bacterial homolog of actin, which polymerizes into filaments similar to F-actin, and plays a vital role in plasmid segregation. ParM filaments segregate plasmids paired at midcell into the individual daughter cells. This subfamily also contains Thermoplasma acidophilum Ta0583, an active ATPase at physiological temperatures, which has a propensity to form filaments.	7.07052e-33
NZ_CP046706.1|WP_114083930.1|121437_122610_-|ParB/RepB/Spo0J-family-partition-protein	gnl|CDD|319251	cd16393, SPO0J_N, Thermus thermophilus stage 0 sporulation protein J-like N-terminal domain, ParB family member. Spo0J (stage 0 sporulation protein J) is a ParB family member, a critical component of the ParABS-type bacterial chromosome segregation system. The Spo0J N-terminal region acts in protein-protein interaction and is adjacent to the DNA-binding domain that binds to parS sites. Two Spo0J bind per parS site, and Spo0J interacts with neighbors via the N-terminal domain to form oligomers via an Arginine-rich patch (RRXR). This superfamily represents the N-terminal domain of ParB, a DNA-binding component of the prokaryotic parABS partitioning system. parABS contributes to the efficient segregation of chromosomes and low-copy number plasmids to daughter cells during prokaryotic cell division. The process includes the parA (Walker box) ATPase, the ParB DNA-binding protein and a parS cis-acting DNA sites. Binding of ParB to centromere-like parS sites is followed by non-specific binding to DNA ("spreading", which has been implicated in gene silencing in plasmid P1) and oligomerization of additional ParB molecules near the parS sites. It has been proposed that ParB-ParB cross-linking compacts the DNA, binds to parA via the N-terminal region, and leads to parA separating the ParB-parS complexes and the recruitment of the SMC (structural maintenance of chromosomes) complexes. The ParB N-terminal domain of Bacillus subtilis and other species contains a Arginine-rich ParB Box II with residues essential for bridging of the ParB-parS complexes. The arginine-rich ParB Box II consensus (I[VIL]AGERR[FYW]RA[AS] identified in several species is partially conserved with this family and related families. Mutations within the basic columns particularly debilitate spreading from the parS sites and impair SMC recruitment. The C-terminal domain contains a HTH DNA-binding motif and is the primary homo-dimerization domain, and binds to parS DNA sites. Additional homo-dimerization contacts are found along the N-terminal domain, but dimerization of the N-terminus may only occur after concentration at ParB-parS foci.	1.76648e-19

Protein sequences

>NZ_CP046706.1|WP_114083931.1|124458_124974_+|hypothetical-protein
MQKLKILPLIITALTALTLTSCSTTTAEQYEATALTSYSWQVKYANDLTSQPQPRIKTFANTSVVNRNGLKPPGAVVGPDDRGLWWPTLPPRPSVDEVEQHKRPQEEAGKPELVKDVKYKLTYGVGNSQQTLPTNYDVYRQVVKAYPQKTPLELTLGVNDNSVEKAEPVSK
>NZ_CP046706.1|WP_114083970.1|124118_124409_+|hypothetical-protein
MPFQDRPEEPELPPEPCQHMQFLDCNSEVGRVIFECYHCKQGIISEYTGDPVMGEYKGRPSVIFTKVKCPNCEQTAIRLQAREVLSITTIPSPWQE
>NZ_CP046706.1|WP_104899617.1|122609_123437_-|ParA-family-protein
MKKKAVKRKIRLDVKSNAGGTGKTTLVTHLAYILGKKGYSVTVIELDPLGSLKIFTGAFSQTEDPPPEKTLASVFRDDFKGNYPLFPIWENKIHNVNVILGGAPLEESIHKIYSHSRKYYLLHDRLEDYPLESDIIILDNPGGLEPMGLVALAAATDILVVMQLEYKALYGSAGLINWFYDKINELRLRPEPKILGFVPSQVNIKKVAAHRNIGEEIPNQLQELGISCFPPIRESNQFINASGVGLPIHLFAPACEAIKDFDPIVTKIIELMSQD
>NZ_CP046706.1|WP_114083930.1|121437_122610_-|ParB/RepB/Spo0J-family-partition-protein
MLKPDISNAFANAGQSQKIHHLTKRVEELEAEINQLRAVEVDSEEKIVLEARIQELVTELADKQGVSEVPINLIDRNPRQPRQTFTKASIQGMAELLRKQGQHTPVILIPLSNGRYLLFDGERRWRSAPEIGWNTLKAVFLLTGIEADDRELHRQALSTTLHREDLNTLDLAESLIQQIIYDYPELSEQKDNIPRLLNAAMSRLERNRKNLELSEIRIASQENQRQWLESVDFKSAEEQKIFDVILALQLNPTSIDTNIFPLLKLSTDLKSAIREEGLEASKARELNKLSATQLKLNEAQSRKIRVQLAQRVIQERLSLSQTKALVKETLSQYKSANISSNENKKVIRTVKTIRSINFEEFHHNQLEEVRQALQSKLQEIDKRIELSNKG
>NZ_CP046706.1|WP_159402674.1|118934_121181_-|ATP-dependent-RecD-like-DNA-helicase
MSTPPNLSPQQINAFPQHETITGVVERLTFYSAESGYTVARLTRPRSTELTTIVGSFANIQPGQTLQLTGFWRDHPQFGPQFQVINYQETKPATLTGIEKYLGSGLIKGVGPVTAKRIVAHFGLETLDIIENQIERLIEVQGIAKKRITLIKNAWSTQKAIKEVMVFLQGHGVSTTYAVKIYKQYKDEAIATVTKNPYQLAADIYGIGFLTADKIARNIGIAPDSEFRYRAGIVHCLSEAAEDGHCYLPQSELIDSVIKLLTTESHQSTEEAVAIIIKDMALAEELIREWDEEKRLLCYKPTYFHTEQNLAQLIRQRLENPVGTDIERVRDWIDRFTASRKIQLSQQQRQAVETAAYSKIMILTGGPGVGKTFTTHTIVSLWKAMGKSIALAAPTGRAAQRLNEMTGLEAKTIHRLLEFDPRSRGFKRDSENPLPHTAIIADEASMLDLFLAYSLVKAVLAGALLLLVGDIDQLPSVGPGQILADLINSGCVPVVRLTQVFRQAQTSAIITAAHQINRGQYPTIEPISDNPVSDCIWHGGGHQPEHGVQAICELITDLLPRLGFNPATDVQVLCPMTRGVVGTRNLNTVLQQLINPPSPSKVEINRGGNLLREGDRIIQLTNDYNREVFNGDLGIIQSIDTVEQEVTVLYGERTVVYDYADLNEIALAWSISIHKSQGSEYPVIVLPIYMQHYMMLTRNLFYTGLTRAKKLVIVVGAKKAISLAVRSTYDQRRYTRLQQRLLQTGLHW
>NZ_CP046706.1|WP_159402673.1|117892_118843_-|RNA-polymerase-sigma-factor,-RpoD/SigA-family
MSSLSSDMVRIYLQEIGQYPLLKPDEEIAYARQVQQMIAIEQSKNELIQQLDREPTMTELANAVEKTETQIRAALHLGQKAKQKMVTANLRLVVSVAKKYQNRNLEFLDLIQEGAIGLQRGIEKFDPNRGYKLSTYAYWWIRQEITRAIAEQSRTIRLPVHITEILTKIKKVQRESFQKLGRHATAEEIASALNISTDKLREYLTASRTAISLNKQVGDEKETELGEILASDAASPEKLLSQELLSQDVAKFLEPLTPIQRQVLTLNFGLENDQHFNLAQIGQQLNLSRERIRQIQVKAISILRHRQSDMQEYLFD
>NZ_CP046706.1|WP_114081260.1|117548_117800_-|hypothetical-protein
MPSKTIDVREYTVRAHKREIHTRVFNFVCKQCEQPTQRETFGVRPLYCERCRPPQAPKQSKLVPIGKRKPRAMNYKSGKDIAG
>NZ_CP046706.1|WP_109012796.1|116570_117158_+|Uma2-family-endonuclease
MNVVTPKRFTIDEYHRLIELEFLKESDRIELIRGELIQMVAKGTPHTVCGSILCRQLDRLLGDRAVIRGQDPITLPSQSEPEPDVAVARGKDEDYLAHHPYPEDIFLVIEISDSTLDYDQTTKLKIYAEAAISDYWIVNLNVRQLERYSQPYQNAQGEFNYLSKQISLPHQSVAIPGFEDVLLDLNRVFPKVVNA
>NZ_CP046706.1|WP_114081261.1|114887_116123_-|AIPR-family-protein
MPKTWNIKIDNYFQANPNCIIATAHVDSFPIDLPLEPNIREPNRKSATYRQMFDSLTTEPEKFFSRHSGIVLSANKTKPVKNKTELELEVLEANEGGSDGIINGGHTVLAFEQAKNYKYDLTEARVKVTIHIGLTEESAKDIALASNTTTPVDSRSKVNARGDYKFIKQYLAQLERAEDRKFRIAYYQNQSGAPRNAQCNVTHLLKLLYCLDRNKYNPDGNKRTKHPAGMSLPSNITDAERERLTALLPLLTHALWIEQRLYEIIQDHISNPRRKGSNDLASIDIRKTTLLPDSKYSFGFGAPTDLALPIIASYRVFLDKDYKWILPFNEFAEDFLQHLWNNYFRKYLVSEKTAGNTVGTKISRNQEIWESLYISAQSYLNQHLVKMVNSSKSEEPKVTQGTKRRVQADKK
>NZ_CP046706.1|WP_159402634.1|113353_114859_+|FAD-dependent-oxidoreductase
MPNISGKHISYWIDSTPTANFPPLINNLSVDVAIVGAGIAGITAATLLKRAGKTVAVIESQQISTGVSGHTTAKVTSLHQLIYADLIKNHGEKKAQIYAQSNQAALEFIAKTVTEQQIDCDFSRQSAYTFAETEDHLKDIEKEVEAALKIGLPATFVRETSLPFPIVGAVKFDNQAQFHSRKYLLHLIKQIPGNGSYVFENTRVLKVDEDNLCQVTTDKGIIQAQNVIVSTNIPITDEGLFFAKTYPKRSYIIGARIAEQKAPVGMYIGSGEKYYSIRTTPDKNGLLLLVGGGGHQVGTVENTEEKYLDLENYARSRFDIDSIDYRWSTQDFVSFDKIPYVGKLTPLSKHTFVATGFSLWGMTQGTLSGMILSDQILGIENPAADLYDSTRATPFLTPQGIKQNLEVGAHWVGDRLKGLNKSLQDVAIGEGKLVTVDGDKVAAYRDQTGEIHAVSAVCSHLGCVVAWNSAEKSWDCPCHGSRFSCKGEVLHGPTVKDLKKF
>NZ_CP046706.1|WP_114083932.1|125386_126346_+|ParM/StbA-family-protein
MSNIHTLQKIFPAGFDNGYGSLKLLVDGFEVVRVPSYITNAEMEDVPGRVVFNGTAYTVGESAFRTGNYFDRNTDNNENKVNNALLTLFGALAHLPHRKAWHLKLVVSLHDVGLANELQKVLNGEYQPILAGKQSDVKIEVLKVVLEGMGALFGHQLPKKLTILDFGNGTTLYSRYNQGKREVHTAYPTGVEVLINDISQKMKHLNGGKIGDASKIRFCLEMGHTRYSRDIDIKDVYSACLKDWYEKYLKKVVNLTLDAKHQGDEIWAIGGGCLLPGFKKLLEKNGFKILDNPVEANVSGLLEMAKAISSKNSPTTSIK
>NZ_CP046706.1|WP_114083933.1|126351_126642_+|hypothetical-protein
MTEKFDLAPIKIRLKENYRERIFTESQQLGKSYLETLYFIIDCYFVFIKAGLATQQVAFTPITTDENRLPSMTSTPFAQEKEEDSSSETFSLDFDL
>NZ_CP046706.1|WP_159402675.1|126772_127456_-|hypothetical-protein
MLPVQEWILEFRLGYLGRYWSLISVAGLFIGFLLCLLIFVPLIINMALDPFRYPDHLVMSAIAAVIFGAILWLGQWLILRQTEMIPRVFALINTVVGISVFSVLVWFNQKSLQWSGGLIEGWRTGLIFLVGGTCTGAATGKALDFYCGRVEQRLIRLERERVEQETQERERLLKERIEKEKLAQERLEAEMAERKRIQPEAAQEEERLWYEQHGKDYADYEYDEEEE
>NZ_CP046706.1|WP_114083935.1|127684_128026_-|hypothetical-protein
MTDAPFPNRLDRIEQIILGVAERQANTQAQLDVLSQEMRELTSNVDRVLGRSAILDDVLLELRDSHEQHQRNFESHQQQAEEHLQAFKEHQRTTNAALQSLESILLQLIRNNS
>NZ_CP046706.1|WP_114083936.1|128315_133106_-|hypothetical-protein
MTLEFKHFDPRLNQWIYVDDNQTSPQSILTEKLSNTLLESYFPNKEFSFGHSDEYSTDENLRNHPDGHILLLSSKTRLLYGEKECLETIQKICPDSKDRGAYGSIFLGTCKNAIHEKLNILVVDDSTENRGENGGILSNDLAYKLVGDCYGQISTQLYDKLTLRQSQQDKSYRVIQHRFGWIEGDGEDTTKYRFGKGTLRPYKLDKIKYADPKNKPKIDIILPISSFKGTDKDRPTRATKPQIKPGLYQQNIWLAEKGQSQQGQMSISQLLASFPQGIKDFAEELELQAEKLASIQDDPRIVAADYCEKYEKRKESLNQSKLKIGELTSLEADVKNLGTNDDLDADEELDDEGTKDDLFMYKLIKADLLGHQQLLETEKVKQELSRFVQSQWRDIALGKTLTFDRGMIIPSKELKNGEICVSWEKNEEKILNFRSPFLNSNGLCVSANKHVEDRLGPDGKDLKGVIVVSDEDHKRIQQRIAQLEALLIDVDFIDPAETESERQARDFDGDCIGVARASLYPNLTAEAERRNLPQNAYSPTVKLKKQSFYDPTDGSQRPFEEIAIHMSDSISVGIINNQVTALEALESEIEVLKTYGTFEQKSTYLDQVSNHYETLFEQERQKEPKLIREEYKPYMQGVVELAHSQRTPETIQQAMDINRQMYRSMIEEGCYQNQIAVDLFKSAKKPEMNKIRENSRYLYRDVNYIKDKKSASAYLRRGITPKGYSPVELLISQTNKYFQESQLESRPIVQFKDLFKGVEFTPQQKFAAIAAKYEFDQKFNTAVRMERLRETEKGPSASIQTPQGMQLEIGNLTRYGHPLIWKAQTLNIRLDEIKFTNSERPHKLLAVAQIDGEIGENGKPAYRNLGTVSQQSVTDHNLKSGMTMQGAKLLELKPELTRSQTKLLFDKAQEAALAFYASIPESEKLALSAAAWNICASRQDELEVARKENANPQAIAKKVSNFAFAAFPNEIISRLEKLQFSEPKLVTLHNEANQFLGRKWNPDEKHPIEIRASHHPPGHERHVSRLLFVCDTDGEYKEFAMLETRTGMLPIGTKGQASFVGVEPATAKATIGLPGNEPIEITIRELKNFSYAGLVFNAEPVNLEFGTVPIPDKTVKIKIDALTLGELDSDSVQQLKEINYLKNGNPLKLKLTSISETGDQAFVLGESPNGNLLKINKINFYDFSGQTFNDQDYRKLTIETSASKTRDAVFLNGEPLGVLHFKKDKDALRQLGLLKTGKLTLAPAIVESNFSVICAQIDANTVEYPQKWTKEFQAFETQSVNSEQQEMIESSANILHQIKERPTFLFSTQSNKKLGVMGLAVDNQKAETVTKWLTAQNVKFSLAPTEDVIRETKKGLAVFNLVDSSIPAKTLESMTKKFGAIIETDSEYQQRVNSLATRPQFLKPPEQTAQSPPNQSTLLLSTTPSTPDISNGVKTEPLSVEKLPTVTIDDLRNWYNAADKLGKSENYKKRIVEVAYGFKAGEQLSAEALTVMNKDKFELEAISRLTQIAQKIGMAWGKSDENGTKVQGKIYDLAFNTQQRDLTILQKDGEVILNLQSGRVQTNKLTPQILQTFEDANTQIDQILAKSQGQQIELQR
>NZ_CP046706.1|WP_114083937.1|133180_133684_+|hypothetical-protein
MNKREFNSDGSLKDEARQQMLATGMSNEAINDYALSLKEEYDEWKHLDETDPEPWPIYTAYDFFTEQEKKEFNRDGSLRPEYVEYARKIGISESTLEHQEWRKRNEVENYDAVSAEHAEQGINFGEERMKERIEDSRTYAQRRRQMEQDLRNFEPEDSLPFDKNTSY
>NZ_CP046706.1|WP_114083938.1|133979_134381_-|hypothetical-protein
MSELQQTKLWDDWDDINLSTPERRIERLEILLCQKVHKGEDISQCLQVLEYLKNCTTHQELESVFFRRTQSKLTFNLWQIIGQATLISLVAISCCFAIYKIATSPISNNSSSELSLGKQLSKNTPPHSKKHHK
>NZ_CP046706.1|WP_114083939.1|134488_135043_-|hypothetical-protein
MENSNGESLESLSDERFSAFFAHADAIAQRVREWNEYRLEQEIADQKRTIDLKIEKASDVKAVEKLKKSKEWLKHRQQRFEKVKELLFWIGAWVGSGCSGTLFFLTAIVTFATLGLIAGLNWPTTIACKSGSGGCYLLRFDKKTVILPQQFKNILAEYERNLNKSKHLKREQGIGNREQGNPHK
>NZ_CP046706.1|WP_147262544.1|134925_135738_-|hypothetical-protein
MPYTKELLQQTYSLSVEDVDATLTASGLAIDQPSYSDEEIQSRFDVIRALIQQGKTYKQAAAHFQRQEKKRADKTEFPPMNILEMLTHIKSEYGIELELTEAIEIISACGLSPNQKEYRQLECERFLEACDLIKEQNKTYFDVATHFGIVQPQDESQLIAEFFGEEASVSEEELINLVDNITRKRAQNIPGLVNQMYLKNVLRALSENKQDIKNFYSGLEQRILERIEGKSPLKTLMANHSNHYPMKDFPLSSPTPMLSPNVSESGTSTD
>NZ_CP046706.1|WP_114083940.1|135748_136129_-|hypothetical-protein
MPEQVDFRFQFSTSSPYLPLLKYLSPKNKTLEFPRQNMIIWAIAAFWHPIACRWLGGFSESDLKSKARISIYQLQQQIIYLAQTFNLEQELESHLIVTNPADKVDTHLSSSPTHEDDDCLLENAFN

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP046706_1	1.1|125147|46|NZ_CP046706|CRISPRCasFinder	125147-125192	46	NZ_CP046706	Nostoc sp. ATCC 53789 plasmid pNsp_c, complete sequence	125147-125192	0	1.0

1. spacer 1.1|125147|46|NZ_CP046706|CRISPRCasFinder matches to NZ_CP046706 (Nostoc sp. ATCC 53789 plasmid pNsp_c, complete sequence) position: , mismatch: 0, identity: 1.0

gtgtaccccaagattatttagaggcttgagcaaaatttgactccca	CRISPR spacer
gtgtaccccaagattatttagaggcttgagcaaaatttgactccca	Protospacer
**********************************************

5. NZ_CP046709

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP046709_1

• CRISPR_ID: NZ_CP046709_1
• CRISPR_location: 41569-41654
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP046709_1

Consensus_repeat	Method
TTTGCAATTAATGTGAGCCAAGTC	CRISPRCasFinder

spacers of NZ_CP046709_1

>1.1|41593|38|NZ_CP046709|CRISPRCasFinder
GGATGATTGCAAGCCCATTGCAAATAATAATGAGTCTG

CRISPR arrays and Neighbor proteins around NZ_CP046709_1

CRISPR arrays

The CRISPR arrays of NZ_CP046709_1

>merge|NZ_CP046709|1|41569-41654|CRISPRCasFinder
TTTGCAATTAATGTGAGCCAAGTCGGATGATTGCAAGCCCATTGCAAATAATAATGAGTCTGTTTGCAATTAATGTGAGCCGAAGT

>NZ_CP046709|1|1|41569-41654|CRISPRCasFinder
TTTGCAATTAATGTGAGCCAAGTC	GGATGATTGCAAGCCCATTGCAAATAATAATGAGTCTG
TTTGCAATTAATGTGAGCCGAAGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046709.1|WP_167756049.1|46138_46300_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046709.1|WP_114085499.1|36079_36334_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046709.1|WP_114080803.1|42160_42358_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046709.1|WP_114080794.1|42514_42703_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046709.1|WP_114085498.1|35795_36083_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046709.1|WP_114080804.1|45605_46031_+|GIY-YIG-nuclease-family-protein	unknown	unknown	gnl|CDD|372608
NZ_CP046709.1|WP_114081251.1|38724_40371_-|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl|CDD|366234
NZ_CP046709.1|WP_114085496.1|34723_34999_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046709.1|WP_114080798.1|46532_47573_+|hypothetical-protein	unknown	unknown	gnl|CDD|374724
NZ_CP046709.1|WP_114080796.1|43357_43810_+|hypothetical-protein	unknown	unknown	gnl|CDD|269814
NZ_CP046709.1|WP_114085502.1|37147_37465_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046709.1|WP_114085501.1|36775_37144_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046709.1|WP_114080799.1|47655_48621_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046709.1|WP_114080793.1|41718_42054_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046709.1|WP_114085500.1|36330_36528_-|hypothetical-protein	unknown	unknown	gnl|CDD|369567
NZ_CP046709.1|WP_114081249.1|37763_38735_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|225806
NZ_CP046709.1|WP_114085497.1|34995_35217_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046709.1|WP_114080795.1|42695_43361_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046709.1|WP_114080797.1|43930_45529_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046709.1|WP_114081250.1|40657_41497_+|tyrosine-type-recombinase/integrase	unknown	unknown	gnl|CDD|274042

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046709.1|WP_114080798.1|46532_47573_+|hypothetical-protein	gnl|CDD|374724	pfam16684, Telomere_res, Telomere resolvase. Telomere resolvase (protelomerase) catalyzes the conversion of linear double-stranded DNA into hairpin telomeres.	9.6567e-07
NZ_CP046709.1|WP_114080796.1|43357_43810_+|hypothetical-protein	gnl|CDD|269814	cd14807, RAP_D2, Domain 2 of receptor-associated protein (RAP). This subfamily is the N-terminal domain (D2) of receptor-associated protein, RAP, an antagonist and a specialized chaperone in the endoplasmic reticulum that binds tightly to members of the low-density lipoprotein (LDL) receptor family and prevents them from associating with other ligands. D2, along with RAP domain 1 (D1), is essential for blocking low-density lipoprotein receptor-related protein (LRP) from binding of certain ligands, such as alpha2-macroglobulin; D1 and D2 each bind LRP weakly but the tandem D1D2 binds much more tightly to the second and the fourth ligand-binding clusters present on LRP, suggesting the avidity effects arising from amino acid residues contributed from each domain. Also, RAP has regions that interact weakly with heparin, one located in D2 and two located in D3. The double module of complement type repeats, CR56, of LRP binds many ligands including alpha2-macroglobulin, which promotes the catabolism of the Abeta-peptide implicated in Alzheimer's disease.	0.00165664
NZ_CP046709.1|WP_114080804.1|45605_46031_+|GIY-YIG-nuclease-family-protein	gnl|CDD|372608	pfam13455, MUG113, Meiotically up-regulated gene 113. This is a family of fungal proteins found to be up-regulated in meiosis.	1.23416e-09
NZ_CP046709.1|WP_114085500.1|36330_36528_-|hypothetical-protein	gnl|CDD|369567	pfam07878, RHH_5, CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5. This family contains bacterial proteins that form a ribbon-helix-helix fold. This fold occurs in many examples of bacterial antitoxins.	8.10342e-08
NZ_CP046709.1|WP_114081249.1|37763_38735_-|AAA-family-ATPase	gnl|CDD|225806	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion].	2.06497e-48
NZ_CP046709.1|WP_114081251.1|38724_40371_-|DDE-type-integrase/transposase/recombinase	gnl|CDD|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	1.79386e-07
NZ_CP046709.1|WP_114081250.1|40657_41497_+|tyrosine-type-recombinase/integrase	gnl|CDD|274042	TIGR02224, Tyrosine_recombinase_XerC, tyrosine recombinase XerC. The phage integrase family describes a number of recombinases with tyrosine active sites that transiently bind covalently to DNA. Many are associated with mobile DNA elements, including phage, transposons, and phase variation loci. This model represents XerC, one of two closely related chromosomal proteins along with XerD (TIGR02225). XerC and XerD are site-specific recombinases which help resolve chromosome dimers to monomers for cell division after DNA replication. In species with a large chromosome and homologs of XerC on other replicons, the chomosomal copy was preferred for building this model. This model does not detect all XerC, as some apparent XerC examples score in the gray zone between trusted (450) and noise (410) cutoffs, along with some XerD examples. XerC and XerD interact with cell division protein FtsK. [DNA metabolism, DNA replication, recombination, and repair].	5.07702e-21

Protein sequences

>NZ_CP046709.1|WP_114081250.1|40657_41497_+|tyrosine-type-recombinase/integrase
MRIIRQLLLWIVEHPGSGGDFQPEQLTKTAMEIYLAYLDTSGYSIAHQARVKSAVSGFARWLIEEKGILRRNPTRGLNIPAQPLLAPRQLTPDQRYILRNLIEKDGHPRSMAVFALGYWAGCRVSDVSWLRIEHTHIGPKVGWLHVGYKGGKARDIDLINAVRKPMYEYIHHGGRDTESDYTFTSQRNERLTEAGIHRWWKNIKAQATVSEWELIHDVTFHDLRHDFAHRAREAGWTLEEVAYYLGHITKKGTPAIQTTVRYTQSSRQQVKDKLALLKG
>NZ_CP046709.1|WP_114081251.1|38724_40371_-|DDE-type-integrase/transposase/recombinase
MPAEALTNLRHRLDMLPSRCQERRQLMEETASLYGVSIDTLYRALRNSSRPKSINRSDSGTPRKLSQAEMELYCEVIAATKIRTCNKKGRHVSTARAIELLEDFGMNTPQGFIKPPKGLLTKATVNRYLKTWGYDHLTMTRQPPAVRFQATHSNECWHFDLSPSDLKHVKQPLWVETGKGNPLLMLYSVVDDRSGVCYQEYHCVYGEDVTAALRFLFNAMTASTSDGCPFQGIPEMIYTDNGPIAKSHVFQNVMDCLGIKLASHLPAGKDGRRVTARSKGKVERPFRTVKEAHETLYHFHEPENEVEANLWLRQYLLNYNDQKHRTEAHSRLEDWLRNLPKSGIRQMCSWERFCTFAREPQRRKVDATARVSVEGVAYEVNPDLAGETVVLWWGLFDNELYVEKGDQRYGPFYPVDGPIPLHRYRKHKKTKTEERADRIADLALKLGLPRTALDKNADLQFLVDKYKEIEPTVTPFKDPDPFQEFTYPTVLFAKLAISDYLAKPLAKLSTEQIAFIDGLLAETLNKKVIIERVRQYFHSNKGGQQNAH
>NZ_CP046709.1|WP_114081249.1|37763_38735_-|AAA-family-ATPase
MLTEVMEHFRLVKEFPKAGYYETDHQKQMFKDIKAAIHSGKLIAITGIIGCGKTTTLRRLFDVLEKEGKILVSKSLSVDKERATLPTLIAALFYDLSTDKEIKIPKDGEKRERELRDLIRKGKKSVALFVDEAHDLHYSTLTGLKRLIEVVEDGGGTLSVVLAGHPKLKNDLRRPTMEEIGYRATVFSLEGIVGNQREYIEWLVSECTISDTPIGEILEAEAIELLATRLLTPLQIEQHLTLALEAAYRVAVKPVTTVIVESVLSKQIDDLEPTLTRHGYDVRGLAEQFNAKPAEIKSLFRGQLDPTRARELQEQMLAAGLPL
>NZ_CP046709.1|WP_114085502.1|37147_37465_+|hypothetical-protein
MAARKRITAAPTQDTVSIHDACLRYMTTEQSLRLALSHVRPDDFDTVKAVSEADLEAIASHFQPQLPEKSPQQEIEPATEQPQNTLSLPQQQQHLTAPTCCGSQT
>NZ_CP046709.1|WP_114085501.1|36775_37144_+|hypothetical-protein
MKPRRSKHSTDLDLFLDFPSTKTYLAEVLGVSRSTLVTWENLAFWRIPSFRDAYPKNHDGSYDRESPLSPYQAWVLGRVGRLMAQLRRGERVKGYIAKNPNDFSRYRYQQAFQQLQKLQKGA
>NZ_CP046709.1|WP_114085500.1|36330_36528_-|hypothetical-protein
MNTDNTMSGRVNVVLTDEVYELVKNLAGTERRSQSQTAAILIEEALEARNLLQKNSLADKGKGAA
>NZ_CP046709.1|WP_114085499.1|36079_36334_-|hypothetical-protein
MNETSATHDTEKPEVSPETLEAVESFTTALNNFNWRADYLKFCEVLGFTPDSYAEEKYQQFRELVSYLDCFDKDAIAKMIEAGK
>NZ_CP046709.1|WP_114085498.1|35795_36083_-|hypothetical-protein
MTDTPQQPSRLDRIEAILATVAEQQATNTQAIAELTDNVTRVLGRSAILDDVLLELRDSHEELKRDFLENQRTTNAALNQLGAILVQLTRVDPQN
>NZ_CP046709.1|WP_114085497.1|34995_35217_-|hypothetical-protein
MQKPLTCDRQGFAIEKLNSILSQILQKSRSSESSNYISDRRLTESVEILENVGFTGDLAIFIIASLQILEVGA
>NZ_CP046709.1|WP_114085496.1|34723_34999_-|hypothetical-protein
MRESCQHCGFEFRLNVVSDRRTGTKYLRADCCDAPLRPCPDPAELLRSANLTPSERDYLQRIANLDWFTSKVASVLLQIEAKVKVSGEVTS
>NZ_CP046709.1|WP_114080793.1|41718_42054_+|hypothetical-protein
MRAATPTQSPTSNAQLTLIDQLAKQAGQEIELVDAISQVKNQLILNNLAVRDAELAEGINQHWQNQKQGYLGAIRDLASLAKEPVAITPDETDLTQEIESIITELGKKLIV
>NZ_CP046709.1|WP_114080803.1|42160_42358_+|hypothetical-protein
MSANSLPELVSQAQELLGQIPQHPQFKGLRFDCDVAIGDVKQYFNYLEWAATADLEVSRFEGFTE
>NZ_CP046709.1|WP_114080794.1|42514_42703_+|hypothetical-protein
MDDLNSQIQDAKTDETELKQVLKKYDLDEELALEFSEIDKAFRQLEIKYQSLLNTRKFFNNG
>NZ_CP046709.1|WP_114080795.1|42695_43361_+|hypothetical-protein
MAKIDTTKAAAKAVAEKLAGRNQNSTSSTNSTSTTPATVPIDSRIPGLLTVTPDLIPGMMPPFQPNQYHISDPLNPPETLPQATQSQLDKGMKIYEGATRSLKLTGAALDLTREKFTVIGKHSKAFDAGIQAATEIEKVKGNYLDYLNQKEVTTQKSVALDVSQVKTIADTNISVYSKDELNQKLLQAQIKAEELRLKTVESQGNLASFKAQLGDYLEVKS
>NZ_CP046709.1|WP_114080796.1|43357_43810_+|hypothetical-protein
MRLSHSLGLSAFSLCAGLLVASRGFTNDIAKLISMLGVGVLPASFITYFIADTKSQRLLNDAESKNKKAGETLHKVIREFERSKSKLANVTSLLETVKDELKEARNTINSLGNSKLENTALIAQLQAKLNQAFTQSQQEKQRIEYLESEC
>NZ_CP046709.1|WP_114080797.1|43930_45529_+|hypothetical-protein
MQLFRRLQSWGEKVAHGHQSKAEIIKSLASSYNENLDEVGEAIASERQNYLLQIELLNERIGQLQQQLQGDLIEPVYGDFGFDINGKIANEIARTLFSDLRLALSVKGFQVKPDGVVDVGYGYSRSVHPKAIVEAISKHSETLAKKLGLFKITSVRKLEITDCILVCYRMEPAIKADEIKLMVGTPDEFINYVTSHPIRYRLIADPGVGKTPTTAVMISEILKAGCTRGNTGKGEKVPHTLVTVSYPGAVGSLKDSNYPLEHFLKYGDTTAAIKSFDDCLDDGNFRVKNPTFAAKFFQIWAWDELDNTLNSCSEPYAAGENLKKILKQFGHNNIGWIVSGQSVMTKQIPGFTNDDRSLFTEIIIGIPKIRHYLNTYGKGKNSESNLAKLTRNLDAIEEYIDQKNGLVTDDARLLRVALVVDSRSPKLYFLPNLDRVSFNYQETEETKRLARLAKSSGTIGNELETGGLKPYTASNSQMVSLPPKTTIGGSHQSGTSPHCPHCGSANLKLQNDDRYRCLGCKKRTVSNKIIWK
>NZ_CP046709.1|WP_114080804.1|45605_46031_+|GIY-YIG-nuclease-family-protein
MEAESYHGLIPGAWLRRCKIGLSRNPEARLDNFHRNQPPCNVKILRTIYVENMAEVEGELHQQFSQCNVELIKSKEWFDFNAVQFMMVNWEFEKRSLYVFSLSELPIKLIIFSMIWLLFVGAIAGRLTSQPPMQPQKQLAK
>NZ_CP046709.1|WP_167756049.1|46138_46300_-|hypothetical-protein
MLLTIAKPQQSQAANDYFDGEFDAAIALPPKTTEGDYWRGYLAKINETGNTPF
>NZ_CP046709.1|WP_114080798.1|46532_47573_+|hypothetical-protein
MSRQLEDSEDLKNTYVDERVQWLLPQFEAIAPYKMNERKKGIRNAALLGWEQLAAIEAKNLKLTYPDDRSESEREYGTALRQITALKKELKSAAKTDLKDDALYNPVLTIITHFGNALSYQFASYKQNQNTRYRETVTERREKINRIEIDLTDSLKYAYNILTDIKNGDDANWLDVSCAIALATGRRMGEVHLSASFEEIDTYTLAFKGQLKGKTRKVRQGDKAVYIRDVIFKIPTLLPAELVCFALQWLDGKGKRFPQTEDPERVNRRFSKTLNESCKQWDIFPKDERTYHKFRAAYLRAAIVNDGNIDPYDFTDFAKAVLGDDDENTINAYKRYEIKPGTLTRI
>NZ_CP046709.1|WP_114080799.1|47655_48621_+|hypothetical-protein
MAKWDEVGQELVKKLGSVKKESTIQKLAVAVIEQIRESYAEPNSRRTPLSKVRKAVLEAFPDTETQEHPWQYFTNKGKGNIERYQHLALKYLTLSTEEWDAVGDEARQQWKAQQQAEKSEQQLKPETQLEKQPKSETKKKFQTVKSTEKETTLNDMNISQLQLDADTQAVVEAAIAHSGITLADFVRKACQVYAKTITGKVKQFSEDLTAVSTEELKSDTYKTHPGRAEELTRRAIYALEIHNNNCTEKSQKWMITQTAIQSLTGSKPATIKAILENYKTRLDDHNAKHELNAYDNRKGGGRQIENEIDLAVLVPNGLDIA

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP046709_1	1.1|41593|38|NZ_CP046709|CRISPRCasFinder	41593-41630	38	NZ_CP046708.1	45893-45930	0	1.0
NZ_CP046709_1	1.1|41593|38|NZ_CP046709|CRISPRCasFinder	41593-41630	38	NZ_CP046708.1	49872-49909	1	0.974
NZ_CP046709_1	1.1|41593|38|NZ_CP046709|CRISPRCasFinder	41593-41630	38	NZ_CP046705.1	76103-76140	0	1.0
NZ_CP046709_1	1.1|41593|38|NZ_CP046709|CRISPRCasFinder	41593-41630	38	NZ_CP046705.1	214667-214704	1	0.974
NZ_CP046709_1	1.1|41593|38|NZ_CP046709|CRISPRCasFinder	41593-41630	38	NZ_CP046705.1	80082-80119	1	0.974
NZ_CP046709_1	1.1|41593|38|NZ_CP046709|CRISPRCasFinder	41593-41630	38	NZ_CP046715.1	171-208	1	0.974
NZ_CP046709_1	1.1|41593|38|NZ_CP046709|CRISPRCasFinder	41593-41630	38	NZ_CP046710.1	35911-35948	1	0.974
NZ_CP046709_1	1.1|41593|38|NZ_CP046709|CRISPRCasFinder	41593-41630	38	NZ_CP046709.1	37614-37651	1	0.974

1. spacer 1.1|41593|38|NZ_CP046709|CRISPRCasFinder matches to position: 45893-45930, mismatch: 0, identity: 1.0

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccattgcaaataataatgagtctg	Protospacer
**************************************

2. spacer 1.1|41593|38|NZ_CP046709|CRISPRCasFinder matches to position: 49872-49909, mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

3. spacer 1.1|41593|38|NZ_CP046709|CRISPRCasFinder matches to position: 76103-76140, mismatch: 0, identity: 1.0

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccattgcaaataataatgagtctg	Protospacer
**************************************

4. spacer 1.1|41593|38|NZ_CP046709|CRISPRCasFinder matches to position: 214667-214704, mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

5. spacer 1.1|41593|38|NZ_CP046709|CRISPRCasFinder matches to position: 80082-80119, mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

6. spacer 1.1|41593|38|NZ_CP046709|CRISPRCasFinder matches to position: 171-208, mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

7. spacer 1.1|41593|38|NZ_CP046709|CRISPRCasFinder matches to position: 35911-35948, mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

8. spacer 1.1|41593|38|NZ_CP046709|CRISPRCasFinder matches to position: 37614-37651, mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP046709_1	1.1|41593|38|NZ_CP046709|CRISPRCasFinder	41593-41630	38	NZ_CP046705	Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence	76103-76140	0	1.0
NZ_CP046709_1	1.1|41593|38|NZ_CP046709|CRISPRCasFinder	41593-41630	38	NZ_CP046705	Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence	218646-218683	0	1.0
NZ_CP046709_1	1.1|41593|38|NZ_CP046709|CRISPRCasFinder	41593-41630	38	NZ_CP046708	Nostoc sp. ATCC 53789 plasmid pNsp_e, complete sequence	45893-45930	0	1.0
NZ_CP046709_1	1.1|41593|38|NZ_CP046709|CRISPRCasFinder	41593-41630	38	NZ_CP046709	Nostoc sp. ATCC 53789 plasmid pNsp_f, complete sequence	41593-41630	0	1.0
NZ_CP046709_1	1.1|41593|38|NZ_CP046709|CRISPRCasFinder	41593-41630	38	NZ_CP046710	Nostoc sp. ATCC 53789 plasmid pNsp_g, complete sequence	39890-39927	0	1.0
NZ_CP046709_1	1.1|41593|38|NZ_CP046709|CRISPRCasFinder	41593-41630	38	NZ_CP046715	Nostoc sp. ATCC 53789 plasmid pNsp_l, complete sequence	4150-4187	0	1.0
NZ_CP046709_1	1.1|41593|38|NZ_CP046709|CRISPRCasFinder	41593-41630	38	NZ_CP046705	Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence	214667-214704	1	0.974
NZ_CP046709_1	1.1|41593|38|NZ_CP046709|CRISPRCasFinder	41593-41630	38	NZ_CP046705	Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence	80082-80119	1	0.974
NZ_CP046709_1	1.1|41593|38|NZ_CP046709|CRISPRCasFinder	41593-41630	38	NZ_CP046708	Nostoc sp. ATCC 53789 plasmid pNsp_e, complete sequence	49872-49909	1	0.974
NZ_CP046709_1	1.1|41593|38|NZ_CP046709|CRISPRCasFinder	41593-41630	38	NZ_CP046709	Nostoc sp. ATCC 53789 plasmid pNsp_f, complete sequence	37614-37651	1	0.974
NZ_CP046709_1	1.1|41593|38|NZ_CP046709|CRISPRCasFinder	41593-41630	38	NZ_CP046710	Nostoc sp. ATCC 53789 plasmid pNsp_g, complete sequence	35911-35948	1	0.974
NZ_CP046709_1	1.1|41593|38|NZ_CP046709|CRISPRCasFinder	41593-41630	38	NZ_CP046715	Nostoc sp. ATCC 53789 plasmid pNsp_l, complete sequence	171-208	1	0.974
NZ_CP046709_1	1.1|41593|38|NZ_CP046709|CRISPRCasFinder	41593-41630	38	AP018278	Calothrix sp. NIES-4101 plasmid plasmid5 DNA, complete genome	21799-21836	3	0.921

1. spacer 1.1|41593|38|NZ_CP046709|CRISPRCasFinder matches to NZ_CP046705 (Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence) position: , mismatch: 0, identity: 1.0

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccattgcaaataataatgagtctg	Protospacer
**************************************

2. spacer 1.1|41593|38|NZ_CP046709|CRISPRCasFinder matches to NZ_CP046705 (Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence) position: , mismatch: 0, identity: 1.0

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccattgcaaataataatgagtctg	Protospacer
**************************************

3. spacer 1.1|41593|38|NZ_CP046709|CRISPRCasFinder matches to NZ_CP046708 (Nostoc sp. ATCC 53789 plasmid pNsp_e, complete sequence) position: , mismatch: 0, identity: 1.0

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccattgcaaataataatgagtctg	Protospacer
**************************************

4. spacer 1.1|41593|38|NZ_CP046709|CRISPRCasFinder matches to NZ_CP046709 (Nostoc sp. ATCC 53789 plasmid pNsp_f, complete sequence) position: , mismatch: 0, identity: 1.0

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccattgcaaataataatgagtctg	Protospacer
**************************************

5. spacer 1.1|41593|38|NZ_CP046709|CRISPRCasFinder matches to NZ_CP046710 (Nostoc sp. ATCC 53789 plasmid pNsp_g, complete sequence) position: , mismatch: 0, identity: 1.0

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccattgcaaataataatgagtctg	Protospacer
**************************************

6. spacer 1.1|41593|38|NZ_CP046709|CRISPRCasFinder matches to NZ_CP046715 (Nostoc sp. ATCC 53789 plasmid pNsp_l, complete sequence) position: , mismatch: 0, identity: 1.0

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccattgcaaataataatgagtctg	Protospacer
**************************************

7. spacer 1.1|41593|38|NZ_CP046709|CRISPRCasFinder matches to NZ_CP046705 (Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence) position: , mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

8. spacer 1.1|41593|38|NZ_CP046709|CRISPRCasFinder matches to NZ_CP046705 (Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence) position: , mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

9. spacer 1.1|41593|38|NZ_CP046709|CRISPRCasFinder matches to NZ_CP046708 (Nostoc sp. ATCC 53789 plasmid pNsp_e, complete sequence) position: , mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

10. spacer 1.1|41593|38|NZ_CP046709|CRISPRCasFinder matches to NZ_CP046709 (Nostoc sp. ATCC 53789 plasmid pNsp_f, complete sequence) position: , mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

11. spacer 1.1|41593|38|NZ_CP046709|CRISPRCasFinder matches to NZ_CP046710 (Nostoc sp. ATCC 53789 plasmid pNsp_g, complete sequence) position: , mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

12. spacer 1.1|41593|38|NZ_CP046709|CRISPRCasFinder matches to NZ_CP046715 (Nostoc sp. ATCC 53789 plasmid pNsp_l, complete sequence) position: , mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

13. spacer 1.1|41593|38|NZ_CP046709|CRISPRCasFinder matches to AP018278 (Calothrix sp. NIES-4101 plasmid plasmid5 DNA, complete genome) position: , mismatch: 3, identity: 0.921

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
tgacgattgcaagcccgttgcaaataataatgagtctg	Protospacer
 **.************.*********************

6. NZ_CP046710

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP046710_1

• CRISPR_ID: NZ_CP046710_1
• CRISPR_location: 39866-39951
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP046710_1

Consensus_repeat	Method
TTTGCAATTAATGTGAGCCAAGTC	CRISPRCasFinder

spacers of NZ_CP046710_1

>1.1|39890|38|NZ_CP046710|CRISPRCasFinder
GGATGATTGCAAGCCCATTGCAAATAATAATGAGTCTG

CRISPR arrays and Neighbor proteins around NZ_CP046710_1

CRISPR arrays

The CRISPR arrays of NZ_CP046710_1

>merge|NZ_CP046710|1|39866-39951|CRISPRCasFinder
TTTGCAATTAATGTGAGCCAAGTCGGATGATTGCAAGCCCATTGCAAATAATAATGAGTCTGTTTGCAATTAATGTGAGCCGAAGT

>NZ_CP046710|1|1|39866-39951|CRISPRCasFinder
TTTGCAATTAATGTGAGCCAAGTC	GGATGATTGCAAGCCCATTGCAAATAATAATGAGTCTG
TTTGCAATTAATGTGAGCCGAAGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046710.1|WP_114085436.1|40653_41370_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046710.1|WP_159402697.1|44824_47935_+|hypothetical-protein	unknown	unknown	gnl|CDD|378029
NZ_CP046710.1|WP_114085429.1|48178_49093_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046710.1|WP_114085427.1|51856_53785_+|asparagine-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl|CDD|223444
NZ_CP046710.1|WP_114080988.1|33577_33784_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046710.1|WP_114085433.1|42242_42479_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046710.1|WP_114085435.1|41369_41780_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046710.1|WP_114085434.1|41781_42039_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046710.1|WP_114085432.1|42523_42805_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046710.1|WP_083782524.1|44099_44249_+|hypothetical-protein	unknown	unknown	gnl|CDD|117819
NZ_CP046710.1|WP_114081249.1|36060_37032_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|225806
NZ_CP046710.1|WP_114080985.1|31474_31969_+|hypothetical-protein	unknown	unknown	gnl|CDD|370635
NZ_CP046710.1|WP_114085431.1|42804_43842_-|ParM/StbA-family-protein	unknown	unknown	gnl|CDD|212669
NZ_CP046710.1|WP_114080987.1|32770_33514_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046710.1|WP_114080989.1|33878_35789_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046710.1|WP_159402696.1|27976_28999_-|relaxase/mobilization-nuclease-domain-containing-protein	unknown	unknown	gnl|CDD|367497
NZ_CP046710.1|WP_114085406.1|28976_29429_-|plasmid-mobilization-relaxosome-protein-MobC	unknown	unknown	gnl|CDD|368576
NZ_CP046710.1|WP_114081251.1|37021_38668_-|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl|CDD|366234
NZ_CP046710.1|WP_114081250.1|38954_39794_+|tyrosine-type-recombinase/integrase	unknown	unknown	gnl|CDD|274042
NZ_CP046710.1|WP_114080986.1|31965_32787_+|hypothetical-protein	unknown	unknown	gnl|CDD|349771

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046710.1|WP_114085431.1|42804_43842_-|ParM/StbA-family-protein	gnl|CDD|212669	cd10227, ParM_like, Plasmid segregation protein ParM and similar proteins. ParM is a plasmid-encoded bacterial homolog of actin, which polymerizes into filaments similar to F-actin, and plays a vital role in plasmid segregation. ParM filaments segregate plasmids paired at midcell into the individual daughter cells. This subfamily also contains Thermoplasma acidophilum Ta0583, an active ATPase at physiological temperatures, which has a propensity to form filaments.	3.52582e-26
NZ_CP046710.1|WP_159402697.1|44824_47935_+|hypothetical-protein	gnl|CDD|378029	pfam08706, D5_N, D5 N terminal like. This domain is found in D5 proteins of DNA viruses and bacteriophage P4 DNA primases phages.	1.47464e-19
NZ_CP046710.1|WP_114085427.1|51856_53785_+|asparagine-synthase-(glutamine-hydrolyzing)	gnl|CDD|223444	COG0367, AsnB, Asparagine synthase (glutamine-hydrolyzing) [Amino acid transport and metabolism].	9.6494e-119
NZ_CP046710.1|WP_114085406.1|28976_29429_-|plasmid-mobilization-relaxosome-protein-MobC	gnl|CDD|368576	pfam05713, MobC, Bacterial mobilisation protein (MobC). This family consists of several bacterial MobC-like, mobilisation proteins. MobC proteins belong to the group of relaxases. Together with MobA and MobB they bind to a single cis-active site of a mobilising plasmid, the origin of transfer (oriT) region. The absence of MobC has several different effects on oriT DNA. Site- and strand-specific nicking by MobA protein is severely reduced, accounting for the lower frequency of mobilisation. The localized DNA strand separation required for this nicking is less affected, but becomes more sensitive to the level of active DNA gyrase in the cell. In addition, strand separation is not efficiently extended through the region containing the nick site. These effects suggest a model in which MobC acts as a molecular wedge for the relaxosome-induced melting of oriT DNA. The effect of MobC on strand separation may be partially complemented by the helical distortion induced by supercoiling. However, MobC extends the melted region through the nick site, thus providing the single-stranded substrate required for cleavage by MobA.	0.00160767
NZ_CP046710.1|WP_114080986.1|31965_32787_+|hypothetical-protein	gnl|CDD|349771	cd05386, TraL, transfer origin protein TraL. The transfer origin protein TraL is member of the SIMIBI superfamily which contains a ATP-binding domain. Proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion. The specific function of TraL protein is unknown.	8.1394e-09
NZ_CP046710.1|WP_083782524.1|44099_44249_+|hypothetical-protein	gnl|CDD|117819	pfam09274, ParG, ParG. Members of this family of plasmid partition proteins adopt a ribbon-helix-helix fold, with a core of four alpha-helices. They are an essential component of the DNA partition complex of the multidrug resistance plasmid TP228.	0.00499379
NZ_CP046710.1|WP_114081250.1|38954_39794_+|tyrosine-type-recombinase/integrase	gnl|CDD|274042	TIGR02224, Tyrosine_recombinase_XerC, tyrosine recombinase XerC. The phage integrase family describes a number of recombinases with tyrosine active sites that transiently bind covalently to DNA. Many are associated with mobile DNA elements, including phage, transposons, and phase variation loci. This model represents XerC, one of two closely related chromosomal proteins along with XerD (TIGR02225). XerC and XerD are site-specific recombinases which help resolve chromosome dimers to monomers for cell division after DNA replication. In species with a large chromosome and homologs of XerC on other replicons, the chomosomal copy was preferred for building this model. This model does not detect all XerC, as some apparent XerC examples score in the gray zone between trusted (450) and noise (410) cutoffs, along with some XerD examples. XerC and XerD interact with cell division protein FtsK. [DNA metabolism, DNA replication, recombination, and repair].	5.07702e-21
NZ_CP046710.1|WP_114081251.1|37021_38668_-|DDE-type-integrase/transposase/recombinase	gnl|CDD|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	1.79386e-07
NZ_CP046710.1|WP_159402696.1|27976_28999_-|relaxase/mobilization-nuclease-domain-containing-protein	gnl|CDD|367497	pfam03432, Relaxase, Relaxase/Mobilisation nuclease domain. Relaxases/mobilisation proteins are required for the horizontal transfer of genetic information contained on plasmids that occurs during bacterial conjugation. The relaxase, in conjunction with several auxiliary proteins, forms the relaxation complex or relaxosome. Relaxases nick duplex DNA in a specific manner by catalyzing trans-esterification.	4.80486e-07
NZ_CP046710.1|WP_114081249.1|36060_37032_-|AAA-family-ATPase	gnl|CDD|225806	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion].	2.06497e-48
NZ_CP046710.1|WP_114080985.1|31474_31969_+|hypothetical-protein	gnl|CDD|370635	pfam09726, Macoilin, Macoilin family. The Macoilin proteins has an N-terminal portion that is composed of 5 trasnmembrane helices, followed by a C-terminal coiled-coil region. Macoilin is a highly conserved protein present in eukaryotes. Macoilin appears to be found in the ER and be involved in the function of neurons.	0.00398669

Protein sequences

>NZ_CP046710.1|WP_114081250.1|38954_39794_+|tyrosine-type-recombinase/integrase
MRIIRQLLLWIVEHPGSGGDFQPEQLTKTAMEIYLAYLDTSGYSIAHQARVKSAVSGFARWLIEEKGILRRNPTRGLNIPAQPLLAPRQLTPDQRYILRNLIEKDGHPRSMAVFALGYWAGCRVSDVSWLRIEHTHIGPKVGWLHVGYKGGKARDIDLINAVRKPMYEYIHHGGRDTESDYTFTSQRNERLTEAGIHRWWKNIKAQATVSEWELIHDVTFHDLRHDFAHRAREAGWTLEEVAYYLGHITKKGTPAIQTTVRYTQSSRQQVKDKLALLKG
>NZ_CP046710.1|WP_114081251.1|37021_38668_-|DDE-type-integrase/transposase/recombinase
MPAEALTNLRHRLDMLPSRCQERRQLMEETASLYGVSIDTLYRALRNSSRPKSINRSDSGTPRKLSQAEMELYCEVIAATKIRTCNKKGRHVSTARAIELLEDFGMNTPQGFIKPPKGLLTKATVNRYLKTWGYDHLTMTRQPPAVRFQATHSNECWHFDLSPSDLKHVKQPLWVETGKGNPLLMLYSVVDDRSGVCYQEYHCVYGEDVTAALRFLFNAMTASTSDGCPFQGIPEMIYTDNGPIAKSHVFQNVMDCLGIKLASHLPAGKDGRRVTARSKGKVERPFRTVKEAHETLYHFHEPENEVEANLWLRQYLLNYNDQKHRTEAHSRLEDWLRNLPKSGIRQMCSWERFCTFAREPQRRKVDATARVSVEGVAYEVNPDLAGETVVLWWGLFDNELYVEKGDQRYGPFYPVDGPIPLHRYRKHKKTKTEERADRIADLALKLGLPRTALDKNADLQFLVDKYKEIEPTVTPFKDPDPFQEFTYPTVLFAKLAISDYLAKPLAKLSTEQIAFIDGLLAETLNKKVIIERVRQYFHSNKGGQQNAH
>NZ_CP046710.1|WP_114081249.1|36060_37032_-|AAA-family-ATPase
MLTEVMEHFRLVKEFPKAGYYETDHQKQMFKDIKAAIHSGKLIAITGIIGCGKTTTLRRLFDVLEKEGKILVSKSLSVDKERATLPTLIAALFYDLSTDKEIKIPKDGEKRERELRDLIRKGKKSVALFVDEAHDLHYSTLTGLKRLIEVVEDGGGTLSVVLAGHPKLKNDLRRPTMEEIGYRATVFSLEGIVGNQREYIEWLVSECTISDTPIGEILEAEAIELLATRLLTPLQIEQHLTLALEAAYRVAVKPVTTVIVESVLSKQIDDLEPTLTRHGYDVRGLAEQFNAKPAEIKSLFRGQLDPTRARELQEQMLAAGLPL
>NZ_CP046710.1|WP_114080989.1|33878_35789_-|hypothetical-protein
MRAATSNNIPKITTKETEHLRESYPSLSHLEAGNIAQWLQERKEQLFEMARVSENEADMTRVLGLLASGIGAVCYAVNPMALVGGLIGGAAWLWFVVEHSNRTKEIAPLPFVRGNFIDALARAGDYDNRSNYQADHLANTVKFLERQSAEEYAFLHAEFENIGQYLTQVEPGKRFYAYRWMFGWFGKLKGRQLPTYQSMALHLQDVTIDSRVNLSEISAIAQAQTQLPPTVDIKQFQSPQIDIRDTRQTSELSKPEELQSSANGLSPETITHLPLANRANALIAALTKSGFQIEDMMSSQVIAIAGTQRGGKGTLAAILAILSLALDSGLNTQYFTAGVDVYPFSCNLISALKYPEKDADGSDKLVARDLLKFLKGLDASEPYSHKNLLLVIDEAMRLLSLLDESDRTWAIQYLLSRFAKCGGTLIIVLHGSNLTSVVGKATAGLADTFKQSVNFIGCVAQSVSAGGLRKINVASGEYFKANPNNFAEPVNGGNLGMIPDWLKIELHPGNGQPDPARTLLKFFPELVQHHQPAVMPRGEKIAPSDAVNQLESIFSKPTQELEIAEVEFVSISEADKEQILNIVTSAVTTPVSFAAIRNSRKWGEEKPSVRYLRSAIAQLIESKQLKGSEKLGFTAF
>NZ_CP046710.1|WP_114080988.1|33577_33784_-|hypothetical-protein
MHPIEFKKKWQLTYDELALVLGYQSDYTVRSWNMNGRHKRNPQQVVYVACRLLDEKWSTQGKLVDSYL
>NZ_CP046710.1|WP_114080987.1|32770_33514_+|hypothetical-protein
MSNNNNGNGNHSNPYSETANSTESSEQGEIKTALGRLYREFESFKQSQKTERERDRAELQAWAQTNLIQNQLLSKAMVTIEMLTGELKNQNLSSHEYEQSNENLRQELTPLMTQLKNMPKSTATLENLEFKGLKTEVLQLKENWGKLLIHTQNLTTAIQDLKNSPPPKPITIEKEVYRSEPISKYGTMGLFSALFTLLIFLGFNQFIPVNISNDIDIYLRAILQRTDYSNAKLQRVEKRLGTDRNRR
>NZ_CP046710.1|WP_114080986.1|31965_32787_+|hypothetical-protein
MKRIVMILGGKGGTGKTAFTRLLLDVMHNKGINYLAYDADTENPELYEYYQNFGHGVRLLNFLEVAEAKRFFTEIKAESPDSIIVDMPGASSNKTREIISKFGLFKIAGDLGYRVTLVTVLNLGYSVITSLKTMAEFCSDKADYVVVKNLCWDKGSGFQRWENSKTSAAIAELKGIEIEMPELDYSTFDTLTEKGLPYSAATEENGFPFGDYLLVSGFLDQAKPELEKAGAYLGLQQPLALVAPESNTSTSKQPKVTASTSRRGQNKTNEQQQ
>NZ_CP046710.1|WP_114080985.1|31474_31969_+|hypothetical-protein
MSRKPKAVPLSKIEDIQTSLKQKAATPKTISLSDLVLSLAKPIQDMLDAGYSYEDVSDVFKGHGVELAASGLKSFHKKATTLTENSSSNSSSDKAVEESVNSDSEPELTDSSTSNNDSVLPVEPDSSPIDSSEPSGSSSTKTSKRNKTTPKTSAQFNITDRSEI
>NZ_CP046710.1|WP_114085406.1|28976_29429_-|plasmid-mobilization-relaxosome-protein-MobC
MQPDPRTNLSNQLADTLTNRSVAPDEKREVTITFRASYAEKARLEQRCSGVVQSDYIRARLFDYPLPHPKLVIPEVNRQAIYELKKIGNNLNQQTRAINEAVKIGSQPLTNEVKSYLKTLEELTTLLEHTRQSLTQPTVEGQRNDYQSQG
>NZ_CP046710.1|WP_159402696.1|27976_28999_-|relaxase/mobilization-nuclease-domain-containing-protein
MITKVKANKSFRGTTKYVLEKEKAKIIGGNMYGQSTNELVEQFTLSAHLNPQLKDPCYHLMLSVPKSDRTLNDDKLANLSQRHLASVIVLSRLQGDESQVKQPDKRIANTKLKQLVDEFIETELPAYDFFIARHSDKEHDHTHIVASRVNNLDGKSIRTWNNYAHSEHSARLLEREFQLTPVQSSWESKQKAMTRNQLERVERDGLPGEEIMRRAIEQVAADKPTMPQLIERLWREHQVKSIVSYYGHGGVRGIKFGIDIGSFNEDGSPRLLWKQGGNLNKYKCSFTKLQSELGINYDPKRDDSEINHLNNFLESVDNNQVNQQIISTIFPKKSSSYSRN
>NZ_CP046710.1|WP_114085436.1|40653_41370_-|hypothetical-protein
MALGTSGAESNSTGNSDGKPKGKKRSLGEIIDFCAKAVVMIVGLPIRAAAAIVNQFVANGGAGRALVGGILFIGGSVISADSTWQLIFTGPPVCPWFEPAWNWLNVPFALFNPLFYLAFMVSVGVQVIEAHALRGKNPDSARRELQDHMVYELETKPSGKIDLVGQLWQDYKTAGTRDRSSAGLVVIAVWTFDIVTTFAARNPFDYTAPLMILGCTLFNIGTMMVGEIGFAIWRLTKD
>NZ_CP046710.1|WP_114085435.1|41369_41780_-|hypothetical-protein
MYKKQLYLALAGVLVCFLPVIIPLVPKLGAYAEAERLKATEGLERQRIEERAKTSDALYEAGVMPTTRKLRITNYFDSSKRNPRPDTTLYLDDEIVDVFDASGRCIGRIEEGIWKWKYKAKEICKSVQNTKPVRRK
>NZ_CP046710.1|WP_114085434.1|41781_42039_-|hypothetical-protein
MAHPVGYYSLSHDNALIKDMCETWGEGLEKMSESDTLWLIAKIAHEAWLECESSTAPSNEAESVLKRLHELKQWEKFALISAMVQ
>NZ_CP046710.1|WP_114085433.1|42242_42479_-|hypothetical-protein
MSDQDTQKTQPSLTTIEIMTIILGCEQTLRFVQASPNYKQIEASERFSTSNDLKIGDAVQALMEIHEAILNIEFYSQV
>NZ_CP046710.1|WP_114085432.1|42523_42805_-|hypothetical-protein
MPMTQTRIVLNPKYKPKAEEILEATGIDNLSQLFTLLLVNYGDCLVNCLKHSHQLPIQSSLVAQTPTQNTLQPPSIKPQLSPQAKKFAPMGSF
>NZ_CP046710.1|WP_114085431.1|42804_43842_-|ParM/StbA-family-protein
MNYAYIQPVYGLSYPPSNGFVSPQHGQIRPRVVFDGGNRFVKWIDPNNVVQCLLSVVKEVSEYQWKRLKPDDQSVLIEIDGKRFVIGRLAQELGGEPTFQTDKCQLASILALAAIQPNPGQTSVHIQQMIVALPNTLNDDDVAAVKRIANHPLTKEFKRNGEYITYTVGEVVPVDETEPAFHYALNQGFFSFPDAKNAIWDLGGGTAIARIYTPNGTMIHDAEVILPGTKALAQQVAVEMKEVYSLDYSPSLQGIMDAIARGDCLYGTDKLDFSSIFEKACDQWVESARREIRSKWAQHLPELGEVLIVGGSADIAAPICATSGDRFKIAPSPQLFNIIAMAYQE
>NZ_CP046710.1|WP_083782524.1|44099_44249_+|hypothetical-protein
MTEKQVFVRGKISESQKARFKAACALINRPMDEVMAELIEEWLKTQDIK
>NZ_CP046710.1|WP_159402697.1|44824_47935_+|hypothetical-protein
MVAILKGQETVGGSVMPGAFASFDIRNFQDQLEPSKAKDKFICPVCGGNDLSIVPETGKYRCFNGCECKHVREAIKPWAEVVAERAGANYTPSLNRNAAKPKRILPKPAPIPDGELGLVMLTSTVTDIPQPKKLTSRPPKDVEGNATETIYPYSESQWVVRYQCPDANKEKGYSKTFRQWHRRLDGTPQMKKGDLPWGAYRIDEALAAAKSVNGTPALLQHEGEGCVEVGRSHGLAGITFQGSGWDKKTITREYQRAIEAGIGLIVFLHDPDDTGLKKLQTCSECAAEVGIAFIGINPHDICPDLPYKSSDIKEILGQMETPEFIRRLEQEIHAAVAQRSLELAESETIEKEVTDLSNFKIDIDPADPEAFYLPVCTAMNLPYSNCVTAGTFDGWAYRKIFPQTEWMVLNSSFYKWSQENNQWQHQDDNKAYKLLADAGESAYKLSYTKTFGWRITKPYETNAHKESAFKYCRSRLEPAEPLPTNTHLLGFNNCVVDLRTGEQMPHRKDFYLTNIIPHDYEANKPCPEVFLKFLNESFGSELVEVIRAFTSMFLDPTAPYGRFPHLIGLSGGGKGTLGRFWSSLFGESGSSSATHFADISTPEGRHQYLSSKRIFGFPDVGGYAEGVRAFYELVDNGPMSGRALFNPVAYSIQWYIRFWIASVSHLQIENAGDGWMRRAYPIPVKNRDITPDPDLWLKLQEVKSDIISWALAMPRAERDRILLSPPSSDRAKNLALEASLYGDSTKSFVDLCLRPSTNATFIPQSRLHSWYVLYCREHGYAPLGMSKFISHLKTVLPHNFKERSWTPTVNGKRERIQSHFAFIEPLAGVFEMKVPEGPPDSSLSKAEFWYCFKDKCLEGGIEEFEEFFHPTKTPEPLHSLPVHPVHPLNTPGLDPGQAESLTQQGCPPCPIVPPQELALQKKDELNSDCGVNQFVNLTDNPSVPKDFVDNLDSLAVTGFEPVQQVSLAENSLDSLDTPAVAGFSPQQDGELINTTQNELSRPSVKVGDKVEFFNDSVHKWQVGIIKSVQLMETYFL
>NZ_CP046710.1|WP_114085429.1|48178_49093_+|hypothetical-protein
MASAELTSLESTQAVPTVETPSDEEQVNVDTSTETEIESTAAIFQAVGVITGSVNFSSDGQSTVTIGSYEYPLYYSKRQWDVLNALKKEIENTGNHNQRLVVYPKAIHFPRREQPHRIAFQLVGFDRGRKLDAVSGELEDLEFKLSGLWQFIPVCSTPCISVFRNFSDERLEFIKQSEPARKVKFMKASHIPLLWKDAPVRPFRFNPKVAKEEQGHAVFVTIKAKFLPGRDVFGFVALTALPKDSAPRYLKASKTDKATVQLAAQKAKPRVQRPSKKHNLGSSNPPLKPILKKKPPLVEGEADK
>NZ_CP046710.1|WP_114085427.1|51856_53785_+|asparagine-synthase-(glutamine-hydrolyzing)
MCGIVALFSKKEPISESSLRLGIDCLKHRGPDGQKFWISPDRRVALGHTRLSIIDLQNGDQPIANQDETLHIIANGEFYDFERIQRDLKQWGYQLTTNSDTEIALHLYSEFGTQCLHHLRGEFAFIIWDERNDLLFAARDRFGIKPLYYSIYNNTLYLASEVKALFAAGVPGSWDHESFWQAECGILAPDRTIFANVYQVPPGYFLLASRSGIQLHRYWDFDYPLINDSLPQYKAEDYIEQLRHTLDEAIQLRLRADVPVGCYLSGGLDSSTVLGMAAHHSSSPIQAFTLAFDHEAYNEEPLAREMAAHTGANLQTIPIRQSDLAEHFADSIWHCEMLCINANTTAKYLLSQAARDAGYKVVLTGEGSDEIFGGYVHFRQDMLLHNQQGQDEQTVQLLLEELKLKNKVSVGLLLAENSSSQALNSVQRLLGFAPAWMRASAEGYVRSVPLYSPDFIAQFLHKDVYRGFFNQIDVQKQLKGREPVHQSLYLWSKTILPNYLLRMLGDGVEMAHSIEGRLPFLDHKVVELVCNMPVALKIRGLTEKYVLREAAKPFITDTMYNRQKHPFLAPPSTFKPNEPLQQLVQDTLRSSGMSSVPFYNHAAVINLLDQLPTMSESQSTSIDVILMKMLSTYILQERFGLT

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP046710_1	1.1|39890|38|NZ_CP046710|CRISPRCasFinder	39890-39927	38	NZ_CP046708.1	45893-45930	0	1.0
NZ_CP046710_1	1.1|39890|38|NZ_CP046710|CRISPRCasFinder	39890-39927	38	NZ_CP046708.1	49872-49909	1	0.974
NZ_CP046710_1	1.1|39890|38|NZ_CP046710|CRISPRCasFinder	39890-39927	38	NZ_CP046705.1	76103-76140	0	1.0
NZ_CP046710_1	1.1|39890|38|NZ_CP046710|CRISPRCasFinder	39890-39927	38	NZ_CP046705.1	214667-214704	1	0.974
NZ_CP046710_1	1.1|39890|38|NZ_CP046710|CRISPRCasFinder	39890-39927	38	NZ_CP046705.1	80082-80119	1	0.974
NZ_CP046710_1	1.1|39890|38|NZ_CP046710|CRISPRCasFinder	39890-39927	38	NZ_CP046715.1	171-208	1	0.974
NZ_CP046710_1	1.1|39890|38|NZ_CP046710|CRISPRCasFinder	39890-39927	38	NZ_CP046710.1	35911-35948	1	0.974
NZ_CP046710_1	1.1|39890|38|NZ_CP046710|CRISPRCasFinder	39890-39927	38	NZ_CP046709.1	37614-37651	1	0.974

1. spacer 1.1|39890|38|NZ_CP046710|CRISPRCasFinder matches to position: 45893-45930, mismatch: 0, identity: 1.0

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccattgcaaataataatgagtctg	Protospacer
**************************************

2. spacer 1.1|39890|38|NZ_CP046710|CRISPRCasFinder matches to position: 49872-49909, mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

3. spacer 1.1|39890|38|NZ_CP046710|CRISPRCasFinder matches to position: 76103-76140, mismatch: 0, identity: 1.0

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccattgcaaataataatgagtctg	Protospacer
**************************************

4. spacer 1.1|39890|38|NZ_CP046710|CRISPRCasFinder matches to position: 214667-214704, mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

5. spacer 1.1|39890|38|NZ_CP046710|CRISPRCasFinder matches to position: 80082-80119, mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

6. spacer 1.1|39890|38|NZ_CP046710|CRISPRCasFinder matches to position: 171-208, mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

7. spacer 1.1|39890|38|NZ_CP046710|CRISPRCasFinder matches to position: 35911-35948, mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

8. spacer 1.1|39890|38|NZ_CP046710|CRISPRCasFinder matches to position: 37614-37651, mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP046710_1	1.1|39890|38|NZ_CP046710|CRISPRCasFinder	39890-39927	38	NZ_CP046705	Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence	76103-76140	0	1.0
NZ_CP046710_1	1.1|39890|38|NZ_CP046710|CRISPRCasFinder	39890-39927	38	NZ_CP046705	Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence	218646-218683	0	1.0
NZ_CP046710_1	1.1|39890|38|NZ_CP046710|CRISPRCasFinder	39890-39927	38	NZ_CP046708	Nostoc sp. ATCC 53789 plasmid pNsp_e, complete sequence	45893-45930	0	1.0
NZ_CP046710_1	1.1|39890|38|NZ_CP046710|CRISPRCasFinder	39890-39927	38	NZ_CP046709	Nostoc sp. ATCC 53789 plasmid pNsp_f, complete sequence	41593-41630	0	1.0
NZ_CP046710_1	1.1|39890|38|NZ_CP046710|CRISPRCasFinder	39890-39927	38	NZ_CP046710	Nostoc sp. ATCC 53789 plasmid pNsp_g, complete sequence	39890-39927	0	1.0
NZ_CP046710_1	1.1|39890|38|NZ_CP046710|CRISPRCasFinder	39890-39927	38	NZ_CP046715	Nostoc sp. ATCC 53789 plasmid pNsp_l, complete sequence	4150-4187	0	1.0
NZ_CP046710_1	1.1|39890|38|NZ_CP046710|CRISPRCasFinder	39890-39927	38	NZ_CP046705	Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence	214667-214704	1	0.974
NZ_CP046710_1	1.1|39890|38|NZ_CP046710|CRISPRCasFinder	39890-39927	38	NZ_CP046705	Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence	80082-80119	1	0.974
NZ_CP046710_1	1.1|39890|38|NZ_CP046710|CRISPRCasFinder	39890-39927	38	NZ_CP046708	Nostoc sp. ATCC 53789 plasmid pNsp_e, complete sequence	49872-49909	1	0.974
NZ_CP046710_1	1.1|39890|38|NZ_CP046710|CRISPRCasFinder	39890-39927	38	NZ_CP046709	Nostoc sp. ATCC 53789 plasmid pNsp_f, complete sequence	37614-37651	1	0.974
NZ_CP046710_1	1.1|39890|38|NZ_CP046710|CRISPRCasFinder	39890-39927	38	NZ_CP046710	Nostoc sp. ATCC 53789 plasmid pNsp_g, complete sequence	35911-35948	1	0.974
NZ_CP046710_1	1.1|39890|38|NZ_CP046710|CRISPRCasFinder	39890-39927	38	NZ_CP046715	Nostoc sp. ATCC 53789 plasmid pNsp_l, complete sequence	171-208	1	0.974
NZ_CP046710_1	1.1|39890|38|NZ_CP046710|CRISPRCasFinder	39890-39927	38	AP018278	Calothrix sp. NIES-4101 plasmid plasmid5 DNA, complete genome	21799-21836	3	0.921

1. spacer 1.1|39890|38|NZ_CP046710|CRISPRCasFinder matches to NZ_CP046705 (Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence) position: , mismatch: 0, identity: 1.0

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccattgcaaataataatgagtctg	Protospacer
**************************************

2. spacer 1.1|39890|38|NZ_CP046710|CRISPRCasFinder matches to NZ_CP046705 (Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence) position: , mismatch: 0, identity: 1.0

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccattgcaaataataatgagtctg	Protospacer
**************************************

3. spacer 1.1|39890|38|NZ_CP046710|CRISPRCasFinder matches to NZ_CP046708 (Nostoc sp. ATCC 53789 plasmid pNsp_e, complete sequence) position: , mismatch: 0, identity: 1.0

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccattgcaaataataatgagtctg	Protospacer
**************************************

4. spacer 1.1|39890|38|NZ_CP046710|CRISPRCasFinder matches to NZ_CP046709 (Nostoc sp. ATCC 53789 plasmid pNsp_f, complete sequence) position: , mismatch: 0, identity: 1.0

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccattgcaaataataatgagtctg	Protospacer
**************************************

5. spacer 1.1|39890|38|NZ_CP046710|CRISPRCasFinder matches to NZ_CP046710 (Nostoc sp. ATCC 53789 plasmid pNsp_g, complete sequence) position: , mismatch: 0, identity: 1.0

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccattgcaaataataatgagtctg	Protospacer
**************************************

6. spacer 1.1|39890|38|NZ_CP046710|CRISPRCasFinder matches to NZ_CP046715 (Nostoc sp. ATCC 53789 plasmid pNsp_l, complete sequence) position: , mismatch: 0, identity: 1.0

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccattgcaaataataatgagtctg	Protospacer
**************************************

7. spacer 1.1|39890|38|NZ_CP046710|CRISPRCasFinder matches to NZ_CP046705 (Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence) position: , mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

8. spacer 1.1|39890|38|NZ_CP046710|CRISPRCasFinder matches to NZ_CP046705 (Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence) position: , mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

9. spacer 1.1|39890|38|NZ_CP046710|CRISPRCasFinder matches to NZ_CP046708 (Nostoc sp. ATCC 53789 plasmid pNsp_e, complete sequence) position: , mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

10. spacer 1.1|39890|38|NZ_CP046710|CRISPRCasFinder matches to NZ_CP046709 (Nostoc sp. ATCC 53789 plasmid pNsp_f, complete sequence) position: , mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

11. spacer 1.1|39890|38|NZ_CP046710|CRISPRCasFinder matches to NZ_CP046710 (Nostoc sp. ATCC 53789 plasmid pNsp_g, complete sequence) position: , mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

12. spacer 1.1|39890|38|NZ_CP046710|CRISPRCasFinder matches to NZ_CP046715 (Nostoc sp. ATCC 53789 plasmid pNsp_l, complete sequence) position: , mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

13. spacer 1.1|39890|38|NZ_CP046710|CRISPRCasFinder matches to AP018278 (Calothrix sp. NIES-4101 plasmid plasmid5 DNA, complete genome) position: , mismatch: 3, identity: 0.921

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
tgacgattgcaagcccgttgcaaataataatgagtctg	Protospacer
 **.************.*********************

7. NZ_CP046708

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP046708_1

• CRISPR_ID: NZ_CP046708_1
• CRISPR_location: 26685-26801
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP046708_1

Consensus_repeat	Method
AGTTGCATTTAATCCTGGCTCAA	CRISPRCasFinder

spacers of NZ_CP046708_1

>1.1|26708|17|NZ_CP046708|CRISPRCasFinder
AGCGATGATTGCAGGTT
>1.2|26748|31|NZ_CP046708|CRISPRCasFinder
TTGCATTTAATCCTGGCTGAAGCACAATTAT

CRISPR arrays and Neighbor proteins around NZ_CP046708_1

CRISPR arrays

The CRISPR arrays of NZ_CP046708_1

>merge|NZ_CP046708|1|26685-26801|CRISPRCasFinder
AGTTGCATTTAATCCTGGCTCAAAGCGATGATTGCAGGTTGGTTGCAAATAATCCTGGCTCAGTTGCATTTAATCCTGGCTGAAGCACAATTATAGTTGCATTTAATCCTGGTTTGT

>NZ_CP046708|1|1|26685-26801|CRISPRCasFinder
AGTTGCATTTAATCCTGGCTCAA	AGCGATGATTGCAGGTT
GGTTGCAAATAATCCTGGCTCAG	TTGCATTTAATCCTGGCTGAAGCACAATTAT
AGTTGCATTTAATCCTGGTTTGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046708.1|WP_114085527.1|27572_28199_-|recombinase-family-protein	unknown	unknown	gnl|CDD|214861
NZ_CP046708.1|WP_114085522.1|23127_23892_+|ParA-family-protein	unknown	unknown	gnl|CDD|224113
NZ_CP046708.1|WP_114080777.1|44003_44516_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046708.1|WP_114080775.1|43135_43459_-|plasmid-mobilization-relaxosome-protein-MobC	unknown	unknown	gnl|CDD|368576
NZ_CP046708.1|WP_114085523.1|23884_24340_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046708.1|WP_114085528.1|28301_31307_+|Tn3-family-transposase	unknown	unknown	gnl|CDD|376561
NZ_CP046708.1|WP_114085533.1|14894_15197_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046708.1|WP_114085519.1|19648_21865_-|TIR-domain-containing-protein	unknown	unknown	gnl|CDD|373105
NZ_CP046708.1|WP_147262582.1|32235_33885_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046708.1|WP_114085525.1|25034_25319_-|type-II-toxin-antitoxin-system-ParD-family-antitoxin	unknown	unknown	gnl|CDD|226136
NZ_CP046708.1|WP_114080774.1|37353_37641_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046708.1|WP_114085526.1|25532_26141_+|tyrosine-type-recombinase/integrase	unknown	unknown	gnl|CDD|334163
NZ_CP046708.1|WP_114085521.1|22276_22720_-|tyrosine-type-recombinase/integrase	unknown	unknown	gnl|CDD|234698
NZ_CP046708.1|WP_159402451.1|35748_36285_-|ISAs1-family-transposase	unknown	unknown	gnl|CDD|227720
NZ_CP046708.1|WP_114081705.1|36281_36839_-|ISAs1-family-transposase	unknown	unknown	gnl|CDD|379382
NZ_CP046708.1|WP_114085524.1|24719_25034_-|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	unknown	unknown	gnl|CDD|226194
NZ_CP046708.1|WP_114085520.1|21866_22187_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046708.1|WP_114085529.1|31650_32052_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046708.1|WP_114085531.1|34167_35706_+|glycoside-hydrolase-family-protein	unknown	unknown	gnl|CDD|381599
NZ_CP046708.1|WP_114085518.1|15294_19623_-|hypothetical-protein	unknown	unknown	gnl|CDD|238121

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046708.1|WP_114085527.1|27572_28199_-|recombinase-family-protein	gnl|CDD|214861	smart00857, Resolvase, Resolvase, N terminal domain. The N-terminal domain of the resolvase family contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase.	1.61436e-41
NZ_CP046708.1|WP_114080775.1|43135_43459_-|plasmid-mobilization-relaxosome-protein-MobC	gnl|CDD|368576	pfam05713, MobC, Bacterial mobilisation protein (MobC). This family consists of several bacterial MobC-like, mobilisation proteins. MobC proteins belong to the group of relaxases. Together with MobA and MobB they bind to a single cis-active site of a mobilising plasmid, the origin of transfer (oriT) region. The absence of MobC has several different effects on oriT DNA. Site- and strand-specific nicking by MobA protein is severely reduced, accounting for the lower frequency of mobilisation. The localized DNA strand separation required for this nicking is less affected, but becomes more sensitive to the level of active DNA gyrase in the cell. In addition, strand separation is not efficiently extended through the region containing the nick site. These effects suggest a model in which MobC acts as a molecular wedge for the relaxosome-induced melting of oriT DNA. The effect of MobC on strand separation may be partially complemented by the helical distortion induced by supercoiling. However, MobC extends the melted region through the nick site, thus providing the single-stranded substrate required for cleavage by MobA.	1.10747e-07
NZ_CP046708.1|WP_159402451.1|35748_36285_-|ISAs1-family-transposase	gnl|CDD|227720	COG5433, COG5433, Transposase [DNA replication, recombination, and repair].	8.75906e-10
NZ_CP046708.1|WP_114085528.1|28301_31307_+|Tn3-family-transposase	gnl|CDD|376561	pfam01526, DDE_Tnp_Tn3, Tn3 transposase DDE domain. This family includes transposases of Tn3, Tn21, Tn1721, Tn2501, Tn3926 transposons from E-coli. The specific binding of the Tn3 transposase to DNA has been demonstrated. Sequence analysis has suggested that the invariant triad of Asp689, Asp765, Glu895 (numbering as in Tn3) may correspond to the D-D-35-E motif previously implicated in the catalysis of numerous transposases.	0
NZ_CP046708.1|WP_114085519.1|19648_21865_-|TIR-domain-containing-protein	gnl|CDD|373105	pfam14516, AAA_35, AAA-like domain. This family of proteins are part of the AAA superfamily.	0
NZ_CP046708.1|WP_114085525.1|25034_25319_-|type-II-toxin-antitoxin-system-ParD-family-antitoxin	gnl|CDD|226136	COG3609, COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain [Transcription].	3.94215e-09
NZ_CP046708.1|WP_114085526.1|25532_26141_+|tyrosine-type-recombinase/integrase	gnl|CDD|334163	pfam00589, Phage_integrase, Phage integrase family. Members of this family cleave DNA substrates by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine residue at the carboxy end of the alignment. The catalytic site residues in CRE recombinase are Arg-173, His-289, Arg-292 and Tyr-324.	5.88223e-23
NZ_CP046708.1|WP_114085521.1|22276_22720_-|tyrosine-type-recombinase/integrase	gnl|CDD|234698	PRK00236, xerC, site-specific tyrosine recombinase XerC; Reviewed.	8.95232e-29
NZ_CP046708.1|WP_114081705.1|36281_36839_-|ISAs1-family-transposase	gnl|CDD|379382	pfam13808, DDE_Tnp_1_assoc, DDE_Tnp_1-associated. This domain is frequently found N-terminal to the transposase, IS family DDE_Tnp_1, pfam01609 and its relatives.	2.94803e-22
NZ_CP046708.1|WP_114085524.1|24719_25034_-|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	gnl|CDD|226194	COG3668, ParE, Plasmid stabilization system protein [General function prediction only].	3.92979e-15
NZ_CP046708.1|WP_114085522.1|23127_23892_+|ParA-family-protein	gnl|CDD|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	8.24246e-36
NZ_CP046708.1|WP_114085531.1|34167_35706_+|glycoside-hydrolase-family-protein	gnl|CDD|381599	cd00737, lyz_endolysin_autolysin, endolysin and autolysin. The dsDNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell walls. Similarly, bacteria produce autolysins to facilitate the biosynthesis of its cell wall heteropolymer peptidoglycan and cell division. Endolysins and autolysins are found in viruses and bacteria, respectively. Both endolysin and autolysin enzymes cleave the glycosidic beta 1,4-bonds between the N-acetylmuramic acid and the N-acetylglucosamine of the peptidoglycan.	9.92177e-65
NZ_CP046708.1|WP_114085518.1|15294_19623_-|hypothetical-protein	gnl|CDD|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	1.89858e-85

Protein sequences

>NZ_CP046708.1|WP_114085526.1|25532_26141_+|tyrosine-type-recombinase/integrase
MKINGFGQAEILKPEEISLLFGEGFVNPRDRALFGVCLYAGARINEVCTLLKGDVITPRGVRPKLIIRSYNTKGGRDTREIQIHPILKDYLEAYAPLIKVRGKNPHLFPGRHGLNHIHQASADRLMREALQRVGLEERGMSTHSFRRTCLTAMSDAGIPLRHIQSISGHRSLAALERYLGVTDQHKENAIAALDFGQTVSPF
>NZ_CP046708.1|WP_114085525.1|25034_25319_-|type-II-toxin-antitoxin-system-ParD-family-antitoxin
MRTTQPLSITLPHDMMEMVKAKVSSGEYATESEVIRDGLRTLQARDAALEKWLHEEVVKSYDECKADESLGIPAEDIVARVRSNYRKRTTQANG
>NZ_CP046708.1|WP_114085524.1|24719_25034_-|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin
MKQYNVIFSPRAERQLDTLYSYIADHSGEERAERYISDIVAFCQRLSLFPERGTKRDDLRPGLRVVGYAKRVTVAFSVESDRVMIHGIFYGGQDYDFMIEADEP
>NZ_CP046708.1|WP_114085523.1|23884_24340_+|hypothetical-protein
MSDVFDRLKKKGARPTVPTRDTSLVKKENTEIVNDQMTEFSHSKNTEEQDSANSEGLKDNPTVSPQEQQSDLPQTVRRTIRLEQDIDTELDVFCTAKKVTRDTFIEAAFIVCSQNEELMQDILEEAKKRYQQRKQAGEQRKFQTMAKKINT
>NZ_CP046708.1|WP_114085522.1|23127_23892_+|ParA-family-protein
MLILTCTSLSGGQGKTTTAILLGRRLAQSGQRVLMVDADPQSNLTFYLGHEVEENQPTLLEVLKKQVSTEDGIYEVGENLWLIPADDGLDKAQEFLSSSGMGAIVLSKRLKEVADLFQYCIIDPPPQRSQICLTAAGAADHIIIPAEASSKGVNSLIRTLALIEELREIDAFSGEILGILPFRDKWVGNNQVAQSKTSIETMRTIAETIPVLPSILESEQFKKAIDKGVTLSSLGFTQLEAPFQQIIEGLQKNV
>NZ_CP046708.1|WP_114085521.1|22276_22720_-|tyrosine-type-recombinase/integrase
MEVWENESDTIHLKWKNLAPRGDSGQVTVLGKGSKTRSVLPLKSIWDNLMQLRGNAADSDPVFCSRKGKGHLDRKTINKIIAAAAKRAGLDAKVSPHWLRHAHATHSLERGANIGLVQQTLGHANVSTTSRYLHARPNDSSSMYLPV
>NZ_CP046708.1|WP_114085520.1|21866_22187_-|hypothetical-protein
MKRIVEFPLENGDSILVEVDEPGLTDERIGLRDEVLEKAKKTFESALEQVKPIANVIMTKVNSLNQPADEVEVKFGIKMSAELGAVIASGNGEVNYEITLKWKRES
>NZ_CP046708.1|WP_114085519.1|19648_21865_-|TIR-domain-containing-protein
MPTPLESSVVRIYSNNSKVVGAGFLVSQKNILTCAHVVADALGIARNTAEMPNAEIRLDFPLLAAKQLFTARIVFWRPVNPNEFAEDIAALELASSPPNTAQPARLVASEELWGHPFRVLGFPKNQSNGVWAAGEIRAGLANGWVQLEDIKQQGYALEPGFSGAPIWDEQLQGVAGMAVAAEMERAAAKAAFIIPTQVLTTAWPELGEQVLSAETMQQQWSTVKSASKNTKVFISYRSQDPDFTLAQQFYEALKASGYEAFMAGESIRLGENWPERIDRELEQSDYFLLLLSQKSATSEMVTEEVRRVKQLQDLRHDHKPVILPIRINFPLNSPLNYDLRGYLQRIQQREWKSSADTPKILQEILTILAEGREPTLTEDELVTTPPAVESPESPPLPVAEPELPEGQVDLASLFYVERSPIESDCYEAILKSGSLIRIKAPRQMGKTSLMARILHQASQQSFLAVSLSFQLADSKVFADLDQFLRWFCAIVGRKLRIPNRLADYWDDIFGSKDNCTAYFEEYLLAQISEPLALGLDEVDLVYQHPEIASDFFGLLRAWHEEAKNGGIWKKLRLIIAHSTEVYIPMNINQSPFNVGLSIELPEFNVEQVQDLTRRHGLNWSSTQIEQLMAMVGGHPYLVRVALYRIARQATTLEELLQVAPTDAGPFGDHLRRHWWNLKQHSDLAMAMKQIVATITPVQLEPIQAFKLKSMGLVELENNNVLPRFNLYLQYFRERAASL
>NZ_CP046708.1|WP_114085518.1|15294_19623_-|hypothetical-protein
MNTAQNPAYEYQVGGSLPIKAPTYIVRQADQDLYEALKAGEFCYVLNSRQMGKSSLRVQVMQRLRAKGFACAAIDLTRIGSQQVTPDQWYAGIVRILVSSFELSKKFNLRSWWPEHDHLSPVQRLSEFIEEVLLSEIDKNIVIFIDEIDGVLNLKDTVGTDDFFAFIRDCYNRRADNPQYRRLTFTLLGVATPSDLIEDKKRTPFNIGRAIELSGFSLEEAQPLVLGLASKVSNPQLMLQKVLAWTGGQPFLTQKLCKLIFVSPPQSDSNEMLWLENLVRSRVIENWETQDEPEHLRTISERILSNEKRAGRLLGLYQQILQQGEVAADDSSEQIELRLSGLIVKQQNYLKVYNRIYQSVFNLNWVNTALANLRPYAELIELWLVSNRQDESRLLRGQALEEAKNWRKDKSLSDLDYQFIDASTELEQRVEKQAKQVLSEAYRKANQRIRIGTVVLGITLVGAVVSGIFILSIIREVQLAKKSTQLEKKGIINLEQFESESVKTLVAAIGNGKELKELVDDNHLEELEEYPTTSPVLALQTILEKMPQPKVLQEKNIVDSASFSPDGQYVLTTVGKTAKVWNLSGQEIAILKGHQGIVNSASFSPDGKYIVTAADDKTAKVWNLSGQEIVTFKGHQGIVNSVSFSPDGKYIVTAADDKTASIWDISGRKIVTLQHQDSVKSASFSPNVKYIVTISAREEKPDDFNKNVTKKTAKVWDLSGQEIATLKKYQDVVINSASFSPDGKYIVTAADDKTASIWDISGRKIVTLQHQDSVKSASFSPNGKYIITTSDPNNTVKVWDLSGQEIVAALGYQDNVYSNSFSPNGKYIVATSDPNNTVKVWDLSGRYILNLNHVNPVNSASFSPDGKRIVTITSDGSARIWLVQPLPLQGYLGTFSPDGKHILTISLDKTAKVWDLSGQEIATLQGNQDIVNSANFSSDGKHILTISLNKTAKVWDLSGQEIATLKGHQDIVNSGNFSPNSQYIVTASLDKTAKVWDLSGQEIATLKGHQGIVNSAVFSPDGKRIVTAADDKTAKVWDISGRNIATLKGHESIVNSASFSPDGKRIVTASNDNTAKVWETSGRNIATLQGHLGMINSASFSPDGQNIVTSSIDNTAKLWSSSGQEIVTLQGHLATVNTASFSPDGKRILTTSLDETARVWSLSGRELANWPDVSKASFSPDGQNILTTSFHNYAYIRSVKNLAQLLTQACDWLQGYIPYRADIRETLKLPTWQQAGKICKFSSSVPLPPSSLTLQKKIVVVVDPGHGLLPDAGTKGLVLEDDVNLSISKKIAEILQQHGVQVVLTRDTYDNFVASSVRDSLSYRVKKAKQVGASLFISIHANAFDGKHDGIETYYLGKNQRLAKVVHSTIIQNISGLRDRGLKSTSFFILKNNSVPAILIETGFIDHPKDGLRLNDINYHNQMADAIASGILKYLQQSDATE
>NZ_CP046708.1|WP_114085533.1|14894_15197_+|hypothetical-protein
MITKEEITIKVPSLVAEAYRNATEEEREQLQVKIAAIMQSQFTTPRLEAIARLRNTMDKASLEAQERGLTPEILESILASPCQTLLKKLESLITEEKDFN
>NZ_CP046708.1|WP_114085527.1|27572_28199_-|recombinase-family-protein
MVQRIAIYCRVSTTDQSCERQERDLLEYAAVCGFEVVGVWKETASGIKHNRSERQKVMALAQSHSIDAILVTEMTRWGRSTIDLIETLQLLHSWHVSLIAQTGLQFDLNTPQGRLIAHLMASLAEFERDLVRERVRSGVAAAKARGQKFGRQPGQRLKADKLGPKVLQMVQQGYSYRKIAEKLNLSKTTVNDIVKRHRQSGSESALEK
>NZ_CP046708.1|WP_114085528.1|28301_31307_+|Tn3-family-transposase
MGFLTLEQRQRYGRYESEPTPMQLARYFHLDDTDFDSVLIRRGNQNRLGFALQLVSVRFLGTFLENPIDVPLGVIIHVATQLGISDIECLPRYLERSVTHWEHQGEIQQLYGYRDFSGQPGHWQLVRWLYGRAWVGSESPSVLFDLVTARLVEHKILLPGVTVLERLVASVRERTAKRLWQILAKIPSKEQRSKLEALLVTDEKTWYTPLDQLRRSPTRHSAPALVNALNRLVKVRSLGINALNFSNIPASRLKALARHAATIRVQAIARMPFERRIATLLAFIHTLEALAADDTLDVLELLIKDLLAKSVRDGKKERLRTIKDLDASALRLGTACAVILDPNCEDKSVREVIFQLIPQEKLQASVSKVEELARPPEDDYYPELLKRWTIVRRFLPSLLRTIDFQATKAGQSILKAVEFLKSIEKKANPLMDTAPLNGITKGWLQLIVQPNADIDRRAYTFCTLERLCEGLRRRELFITPSIRWSNPHAKLLQGSYWESARPQVCRALNLQPTPAAELSKLKQQLDEAFHRTANNLPSNAAVRVEPNKKGRDTLTVTNLDKLEEPASLKALKILVAELLPRVDLPEALLEIHAKTGFMDEFNHGSQDSSRVTDLHISVCAVLIAQSCNIGLKPVTRADIPALTRNRLAWIQQNYLRSETLKSANARLVDAQTHIPLAQTWGGGEVASADGLRFVVPVQTLNSGPNSKYFGRGRGITYYNFTSDQFTGFHGLVVPGTLRDSLVVLVGLLEQQTSLRPKEIMTDTSGYSDVIFGLFWLLGYQFSPRLADVGEARFWRLDSEADYGVLNGIARQRVNTSFIENYWDDMLRVAGSLKLGTVSATDIMRTLYRGEKPSVLGRAIGELGRIAKTLYLLNYVDDEAYRRRILTQLNRGEGRHGLARVIFHGQKGELRQRYREGQEDQLSALGLVVNALVLWNTYYMDAALSSIGSQQSMNLEDLARLSPLGHSHINMLGRYHFSLPLAVMQGEMRSLRDPKDPNEQDD
>NZ_CP046708.1|WP_114085529.1|31650_32052_+|hypothetical-protein
MSSSSIVIINPQKCRPFLLKVMVYSPEAGYKFIIEIQKACTANNEEVWKLLFDLYKKIDNNFVEIISVEYVAGDPNEIEKVAAITDEGMKRSQVREFRENVYPVVKTIAVKGETPTTEDQKNANLVIKNAVLA
>NZ_CP046708.1|WP_147262582.1|32235_33885_+|hypothetical-protein
MDFIVRSVRIEGKWIPNDLLEIIKNTVNIGEQYSPANVSDAQTKVSEWFEEKENNFNLSNGAYSILYVDSETCDVSDETNPKQVEIVIHPYSVRVDLLSVGNNVLPIPRVNTPSFSTGVPSELLATLPVIGILADRNYSESLYLQTTTDLLNLPPRTTTDNGDQTTNLNLNLSARRSLSQPFYNLNTGLEYTHFNYSGQPGENISISYGNRFEPLGEGQNWREQVQIEGGIQGRLDQSFFDAYALGSSVRLLQNIYNLRNSDPVQNSDIGLKLYALGDSRIGNGFGRMGVWFDSGFPSNSSSYQRLAVRAGYATELGHGHNTIGLEIIAGSGYAWGNSPEYSRFFGGNSVSNYLYEQLGDAQVKDFPSGPILRSFGEQQAGLRGSNGLVSGGNFYWHINLNLTFPIAQWSKPLIPDIEIDNGRTLRSILKGQVNTARNSIAVYLEEQGYSSEEADNRADRIVKRDIAPTVNYIADHANIYSIKPMLLFDAAQISGNNGLGSTTWAAVGAGIQVNIINGSLETGYMQTIAPASDSSVGNFFLRLVLHNFP
>NZ_CP046708.1|WP_114085531.1|34167_35706_+|glycoside-hydrolase-family-protein
MNISQNCLDLIKKWEGFSAKAYLDPVNIPTIGYGTIRYPNGQKVQMGDVISEPEAEDLMKLECDEFAEIVNRNVQVTLNQNQFDALVSFCYNVGAAGFKGSTLLKKLNAGNYSEAGEQFLVWNKATKDGVKKVIDGLTNRRKDEKALFEETVGNGTPLEKAEPSPQNEVTWLEGYRESISDDNTIIVARKGKDVVEILTLESPKKEDLITVLRQYPNAQNFLLATSKAVPSGERILIEKRQPASITKVENPPSLQNPLLIMGMGAEDGTLASVKEDIEKLQTRLRDLGYYQGEIDGNFGFNTDQAVKVFQARYFGQNEADGKVGSLTWEKLWGQDAPPIPTPPASPTNPGKNYLKLTKTRQKDEYGCLVLKMEYYKDGQLKDSLNVCSGTPGQQVFKTGPNSVPKSLQPLPEGKWRIEDIKWAKEKDKYFGEFSTPGVGPVSTPLTYVGPSSTRRSAIEIHIDSNRRAGFPGTAGCVGLYTIADYQRFVSWLRETDPRDFYVDWGLGTSPKP
>NZ_CP046708.1|WP_159402451.1|35748_36285_-|ISAs1-family-transposase
MIIKSCNDYVIAVKNNQPKLHSHIQRIAALRKPTSRIVETEKIRDRLTTRTVEVFHEIKGIDPKWIGINSLIRVERVGTRKGKKYHEIVCYISSLLGTAKEFAIGIRGHWGIENRLHWVKDVVFKEDSSTIRMGNAPANLSITRAIALNIIRRNSYASITIAHRFLSHDIDKLLALVE
>NZ_CP046708.1|WP_114081705.1|36281_36839_-|ISAs1-family-transposase
MGANLIEQLKQVEDFRTKDGRRHPLWLVLLFVIMGTMNGYVGYRGWGDFVNRHSRVLIKKFGIQKHGVPSYSTIRRVVMGVEFDKLAEKFNDWAKSYVEIEELEWCAMDGKSIKGTVKDYNSSQQNFVSIVSVFACKRGLVVGMKKFENHDKSEIQVVQDLITAMDLQGVVFSFDSLHCQKKLVR
>NZ_CP046708.1|WP_114080774.1|37353_37641_+|hypothetical-protein
MSPYLDGVSEEVYAGVIAEWANQNPNFLVSILNRENLSIRQSVLSSLDFGLGVINSPERQNFETFLQHLSPQNPTLRDWHQRIPVYPTDTLPNKR
>NZ_CP046708.1|WP_114080775.1|43135_43459_-|plasmid-mobilization-relaxosome-protein-MobC
MIRSKAEDTSMSLAELTRRCILLRQIPPPPPRLGRVTVDTYLELLRIGNNINQLAKATNTAIKMQLPPPASPELLQELLELLRHCQREIANTFIEESDEETDDWQPD
>NZ_CP046708.1|WP_114080777.1|44003_44516_+|hypothetical-protein
MPKSKIPEALDALRALGAKELDDIPARAAIKKMRRQIERVLRLGYSYEEVSKTLAPLDINISPERIRYLLNDIRRSTRKKSVTPPSEENTSTQVIDEPALDENSATEQSSSQSVEKSESKSQPESKPASSKSTTSKTPKTAKKTSDDKAPENQNSSRLAFVPEIINDEDL

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP046708_1	1.2|26748|31|NZ_CP046708|CRISPRCasFinder	26748-26778	31	NZ_CP046708	Nostoc sp. ATCC 53789 plasmid pNsp_e, complete sequence	26748-26778	0	1.0
NZ_CP046708_1	1.2|26748|31|NZ_CP046708|CRISPRCasFinder	26748-26778	31	AP018321	Nostoc sp. HK-01 plasmid plasmid3 DNA, complete genome	4377-4407	0	1.0
NZ_CP046708_1	1.2|26748|31|NZ_CP046708|CRISPRCasFinder	26748-26778	31	NZ_CP023279	Nostoc sp. CENA543 plasmid pCENA543c, complete sequence	31336-31366	2	0.935
NZ_CP046708_1	1.2|26748|31|NZ_CP046708|CRISPRCasFinder	26748-26778	31	AP018277	Calothrix sp. NIES-4101 plasmid plasmid4 DNA, complete genome	23221-23251	2	0.935
NZ_CP046708_1	1.2|26748|31|NZ_CP046708|CRISPRCasFinder	26748-26778	31	AP018324	Nostoc sp. HK-01 plasmid plasmid6 DNA, complete genome	2483-2513	7	0.774
NZ_CP046708_1	1.2|26748|31|NZ_CP046708|CRISPRCasFinder	26748-26778	31	MN694416	Marine virus AFVG_250M895, complete genome	22583-22613	8	0.742

1. spacer 1.2|26748|31|NZ_CP046708|CRISPRCasFinder matches to NZ_CP046708 (Nostoc sp. ATCC 53789 plasmid pNsp_e, complete sequence) position: , mismatch: 0, identity: 1.0

ttgcatttaatcctggctgaagcacaattat	CRISPR spacer
ttgcatttaatcctggctgaagcacaattat	Protospacer
*******************************

2. spacer 1.2|26748|31|NZ_CP046708|CRISPRCasFinder matches to AP018321 (Nostoc sp. HK-01 plasmid plasmid3 DNA, complete genome) position: , mismatch: 0, identity: 1.0

ttgcatttaatcctggctgaagcacaattat	CRISPR spacer
ttgcatttaatcctggctgaagcacaattat	Protospacer
*******************************

3. spacer 1.2|26748|31|NZ_CP046708|CRISPRCasFinder matches to NZ_CP023279 (Nostoc sp. CENA543 plasmid pCENA543c, complete sequence) position: , mismatch: 2, identity: 0.935

ttgcatttaatcctggctgaagcacaattat	CRISPR spacer
ttgcaaataatcctggctgaagcacaattat	Protospacer
*****  ************************

4. spacer 1.2|26748|31|NZ_CP046708|CRISPRCasFinder matches to AP018277 (Calothrix sp. NIES-4101 plasmid plasmid4 DNA, complete genome) position: , mismatch: 2, identity: 0.935

ttgcatttaatcctggctgaagcacaattat	CRISPR spacer
ttgcatttaatcctggctgagacacaattat	Protospacer
********************..*********

5. spacer 1.2|26748|31|NZ_CP046708|CRISPRCasFinder matches to AP018324 (Nostoc sp. HK-01 plasmid plasmid6 DNA, complete genome) position: , mismatch: 7, identity: 0.774

ttgcatttaatcctggctgaagcacaattat	CRISPR spacer
agacccttaatcctggctgaagcgtaattat	Protospacer
  .* .*****************..******

6. spacer 1.2|26748|31|NZ_CP046708|CRISPRCasFinder matches to MN694416 (Marine virus AFVG_250M895, complete genome) position: , mismatch: 8, identity: 0.742

ttgcatttaatcctggctgaagcacaattat	CRISPR spacer
aaccttttattcctggctgaagcacaaatcc	Protospacer
   * **** ***************** * .

8. NZ_CP046705

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP046705_1

• CRISPR_ID: NZ_CP046705_1
• CRISPR_location: 67816-67946
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP046705_1

Consensus_repeat	Method
GTTTGCAGACTAAGTGAAATTTT	CRISPRCasFinder

spacers of NZ_CP046705_1

>1.1|67839|32|NZ_CP046705|CRISPRCasFinder
TTTAACGCAGTAATAAGGGTTTGGGCAACCTT
>1.2|67894|30|NZ_CP046705|CRISPRCasFinder
TTTGCAGACTAAGTGAAATTTTCCTCCTAA

CRISPR arrays and Neighbor proteins around NZ_CP046705_1

CRISPR arrays

The CRISPR arrays of NZ_CP046705_1

>merge|NZ_CP046705|1|67816-67946|CRISPRCasFinder
GTTTGCAGACTAAGTGAAATTTTTTTAACGCAGTAATAAGGGTTTGGGCAACCTTTGTTGCAGACTAAATGAAATTTTTTTGCAGACTAAGTGAAATTTTCCTCCTAAATTCGCAGACTAAATGAAATTTT

>NZ_CP046705|1|1|67816-67946|CRISPRCasFinder
GTTTGCAGACTAAGTGAAATTTT	TTTAACGCAGTAATAAGGGTTTGGGCAACCTT
TGTTGCAGACTAAATGAAATTTT	TTTGCAGACTAAGTGAAATTTTCCTCCTAA
ATTCGCAGACTAAATGAAATTTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046705.1|WP_094344691.1|52967_53585_-|glutathione-S-transferase	unknown	unknown	gnl|CDD|198315
NZ_CP046705.1|WP_114081263.1|74643_75546_-|TniQ-family-protein	unknown	unknown	gnl|CDD|377670
NZ_CP046705.1|WP_114081710.1|72232_73170_-|IS630-family-transposase	unknown	unknown	gnl|CDD|379154
NZ_CP046705.1|WP_114084682.1|64645_66292_-|mechanosensitive-ion-channel	unknown	unknown	gnl|CDD|225803
NZ_CP046705.1|WP_114084680.1|61653_63666_-|caspase-family-protein	unknown	unknown	gnl|CDD|334197
NZ_CP046705.1|WP_114084683.1|66467_67106_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046705.1|WP_114084685.1|69249_70365_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|379165
NZ_CP046705.1|WP_114081250.1|76235_77075_-|tyrosine-type-recombinase/integrase	unknown	unknown	gnl|CDD|274042
NZ_CP046705.1|WP_114084678.1|53738_54308_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_CP046705.1|WP_114081251.1|77361_79008_+|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl|CDD|366234
NZ_CP046705.1|WP_114084679.1|56925_59592_-|WD40-repeat-domain-containing-protein	unknown	unknown	gnl|CDD|238121
NZ_CP046705.1|WP_114084686.1|70364_72146_-|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl|CDD|366234
NZ_CP046705.1|WP_114081264.1|73198_74257_-|hypothetical-protein	unknown	unknown	gnl|CDD|378037
NZ_CP046705.1|WP_147262468.1|75535_76018_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046705.1|WP_114084688.1|59648_61517_-|NACHT-domain-containing-protein	unknown	unknown	gnl|CDD|334197
NZ_CP046705.1|WP_114084684.1|68342_69260_-|TniQ-family-protein	unknown	unknown	gnl|CDD|377670
NZ_CP046705.1|WP_114081249.1|78997_79969_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|225806
NZ_CP046705.1|WP_094344690.1|52361_52958_-|pyridoxamine-5'-phosphate-oxidase	unknown	unknown	gnl|CDD|226105
NZ_CP046705.1|WP_114084687.1|54379_54790_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046705.1|WP_114084681.1|64331_64625_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046705.1|WP_094344691.1|52967_53585_-|glutathione-S-transferase	gnl|CDD|198315	cd03206, GST_C_7, C-terminal, alpha helical domain of an unknown subfamily 7 of Glutathione S-transferases. Glutathione S-transferase (GST) C-terminal domain family, unknown subfamily 7; composed of uncharacterized proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. GSTs also show GSH peroxidase activity and are involved in the synthesis of prostaglandins and leukotrienes. The GST fold contains an N-terminal thioredoxin-fold domain and a C-terminal alpha helical domain, with an active site located in a cleft between the two domains. GSH binds to the N-terminal domain while the hydrophobic substrate occupies a pocket in the C-terminal domain.	5.19226e-44
NZ_CP046705.1|WP_114081263.1|74643_75546_-|TniQ-family-protein	gnl|CDD|377670	pfam06527, TniQ, TniQ. This family consists of several bacterial TniQ proteins. TniQ along with TniA and B is involved in the transposition of the mercury-resistance transposon Tn5053 which carries the mer operon. It has been suggested that the tni genes are involved in the dissemination of integrons.	6.80838e-11
NZ_CP046705.1|WP_114081710.1|72232_73170_-|IS630-family-transposase	gnl|CDD|379154	pfam13384, HTH_23, Homeodomain-like domain.	1.01748e-09
NZ_CP046705.1|WP_114084682.1|64645_66292_-|mechanosensitive-ion-channel	gnl|CDD|225803	COG3264, COG3264, Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane].	1.26066e-80
NZ_CP046705.1|WP_114084686.1|70364_72146_-|DDE-type-integrase/transposase/recombinase	gnl|CDD|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	3.76114e-12
NZ_CP046705.1|WP_114084685.1|69249_70365_-|AAA-family-ATPase	gnl|CDD|379165	pfam13401, AAA_22, AAA domain.	9.30633e-10
NZ_CP046705.1|WP_114081250.1|76235_77075_-|tyrosine-type-recombinase/integrase	gnl|CDD|274042	TIGR02224, Tyrosine_recombinase_XerC, tyrosine recombinase XerC. The phage integrase family describes a number of recombinases with tyrosine active sites that transiently bind covalently to DNA. Many are associated with mobile DNA elements, including phage, transposons, and phase variation loci. This model represents XerC, one of two closely related chromosomal proteins along with XerD (TIGR02225). XerC and XerD are site-specific recombinases which help resolve chromosome dimers to monomers for cell division after DNA replication. In species with a large chromosome and homologs of XerC on other replicons, the chomosomal copy was preferred for building this model. This model does not detect all XerC, as some apparent XerC examples score in the gray zone between trusted (450) and noise (410) cutoffs, along with some XerD examples. XerC and XerD interact with cell division protein FtsK. [DNA metabolism, DNA replication, recombination, and repair].	5.07702e-21
NZ_CP046705.1|WP_114084678.1|53738_54308_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	6.34878e-12
NZ_CP046705.1|WP_114081251.1|77361_79008_+|DDE-type-integrase/transposase/recombinase	gnl|CDD|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	1.79386e-07
NZ_CP046705.1|WP_114084679.1|56925_59592_-|WD40-repeat-domain-containing-protein	gnl|CDD|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	6.69354e-46
NZ_CP046705.1|WP_114084680.1|61653_63666_-|caspase-family-protein	gnl|CDD|334197	pfam00656, Peptidase_C14, Caspase domain.	9.00604e-21
NZ_CP046705.1|WP_114084688.1|59648_61517_-|NACHT-domain-containing-protein	gnl|CDD|334197	pfam00656, Peptidase_C14, Caspase domain.	1.90345e-12
NZ_CP046705.1|WP_114084684.1|68342_69260_-|TniQ-family-protein	gnl|CDD|377670	pfam06527, TniQ, TniQ. This family consists of several bacterial TniQ proteins. TniQ along with TniA and B is involved in the transposition of the mercury-resistance transposon Tn5053 which carries the mer operon. It has been suggested that the tni genes are involved in the dissemination of integrons.	3.59513e-12
NZ_CP046705.1|WP_114081249.1|78997_79969_+|AAA-family-ATPase	gnl|CDD|225806	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion].	2.06497e-48
NZ_CP046705.1|WP_094344690.1|52361_52958_-|pyridoxamine-5'-phosphate-oxidase	gnl|CDD|226105	COG3576, COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase [General function prediction only].	6.49546e-16
NZ_CP046705.1|WP_114081264.1|73198_74257_-|hypothetical-protein	gnl|CDD|378037	pfam08722, Tn7_Tnp_TnsA_N, TnsA endonuclease N terminal. The Tn7 transposase is composed of proteins TnsA and TnsB. DNA breakage at the 5' end of the transposon is carried out by TnsA, and breakage and joining at the 3' end is carried out by TnsB. The N terminal domain of TnsA is catalytic.	1.81638e-10

Protein sequences

>NZ_CP046705.1|WP_114084683.1|66467_67106_+|hypothetical-protein
MGKRKRKNHNPPFPWMVEEDNLFIAPTGNEIVTDAGWEKISFEEARKLFSPETFQEWYELFLENTDISEILSESNIDIDLDDESVIDNFLQRSNWAPKQVNLVVAKAIYKNYAWVRGLMISTPDVEEPYFHNYEMEAIRLGVKLRKYIKEDIPVINDCKDAVRHLHGRYTLIGWQPRNCVTAAHNLKISKATKVYSQLLWDEDWVDEEDEIY
>NZ_CP046705.1|WP_114084682.1|64645_66292_-|mechanosensitive-ion-channel
MFDFHRLRLPLKYLNILITVLTFVLFFWFTPVVSQALTKAPVILDGQQLFQISDSGQYSAQERTNLINSQLKNVISASEPIQVKIEKRNQLPTILLNDRYLLTVTQQDTLPGSTLDEQANIWARQIKEALQQAHLERTRTYLQQTTFIAAVILLITVGFSWLLGWIKHQFIRVASLRLTTSNAIPNSETLKVLELFFKLVLASMRLALWMSAILYITNLFPFTRQWSYQISNILITSFTSPILTLGKNPYSLTELIVLVGLLFGLVIFAGTLTNFLRSRILSFTVINRGAQEAIIILLKYGLIFIGTLVLLQIWGLDISSLTILASALSVGIGFGLQDIAKNFGSGLVLVFERPIQVGDFVEVGEYTGIVERIGARSTEIRTLDHVSIIVPNSRFLEKEVINWSHRNPISRLHLPVGVAYSSDPKAVQSALLEAASKHPNVLQTPLPLVLFKEFAKNTLNFELLVWTAEPNKQFLLKSDLYYIIYEVLQQRKIEIPFAQLDLHLRSGKLEFTPEMQLALIQMVEGLSNQESDIDSTNPIEKGTEGIDA
>NZ_CP046705.1|WP_114084681.1|64331_64625_+|hypothetical-protein
MKTSNEIHTKKIIKKSDKLTLRQMKLIEEAEDQLLQANTANSPAPVVEVEEKPVAISEPRVPDYIPLLDNPPVQSVGNSGWQVSDVWRDIRVDDFCG
>NZ_CP046705.1|WP_114084680.1|61653_63666_-|caspase-family-protein
MGGNIYALLVGIDEYLNVSPLQGCVNDITAIKEYLEGRVNTDRYQVHLRTLLNKDATRQRIIDCFRQHLCQAGSEDMAFFYYAGHGSQEEASEEFWTIEPDRLNETLVCYDSRSPGGWDLADKEMAKLIAEIAQKNPCITIIMDCCHSSSGTRGDIEADTAERKAPIDRRKRPLESFILSNKDAEQLSTERSLANNSTGWTLPRAKHIFLAACRDHETAKEYNADGQRRGAFSYFLLDTLKKANGSLTYRDLFKRTNALVRSKVANQSPQLEATVLNDLEQPFLGGAIAGRKPYLTVSYHKDHEWVVDGGTVHGIPQPSGDETTLLALFPFDSSPEQMQELSAAICEAKVIAVMPQLSLVQISGIETLEPDMTFKAVVTSLPLPPKGVLITGESAGVKLACAALLAIGTEKPSSLYLKEVAKPEDAELKLLACNGQYLITRPADDHSIVAPIQGYTEENALQAIERLEHIARWTNIAELSSPATSSIQASAVQMVIYQEGEEIKDAQISFQYQQQNGKLKSPTFKVKLKNTSSRELFCALLNLTDSYAVDPQLLETGGVWLKPGEEAWALRGENIYPTVPEKLWKQGITQSQDILKLIVSTAEFDPTLLRQNELDLPFFPQREVNRGRGTLNRLMKRVQSRELRYAPEEEELYDDWITNQINITTVRPKV
>NZ_CP046705.1|WP_114084688.1|59648_61517_-|NACHT-domain-containing-protein
MYEFSRNLAFIIGINNYTNGLSSLQNATNDAKKLVEVLRKKHSYQVWVCLDEVATLKSLKNFLEKTLPQHVTADDRLLFYFAGHGIALNGNDGPEGYLIPQDAKLGDTKTYLPMTYLQEYLSDLPCRHFLGILDCCFAGAFRWSTTRDLLVAPEVIHKERYDRFITDPAWQIITSAAYDQKALDAFNLNTERGHIDGHSPFAAALLEALTGSADVYPTASNGKPSGDGIITATELYLYLRDAVEPATQENRQRQTPGIWPMKKHDKGEYIFLTPGHPLNLPPAPPLDESQNPYRGLQSYEEKHSHLFFGRQALSRKLYDFISQQPLTVVMGASGTGKSSLVKAGLIPYIKQLDAKSNLPLWHILSPMRPGETPLKTLINTLTSDNLPISSINALTLEQKVETFLSSLATWSQFNSNSKVLLIIDQAEELVTLCRDEQEREKFLDLLGQAVAKYSQNIRLLLTLRIDFEPQVQNSALKLHWQAARFIVPAMTREELRSCIEEPASIRVMYFEPHNLVEQLIDEVAQMPGALPLLSFTLSELYLRYLRTIRKGRRYNRAITQADYEELGGVTRSFTQRADSEYEELIKQDKAYEQTIRNVMLRMVAVGEGELARRRVLLGISKK
>NZ_CP046705.1|WP_114084679.1|56925_59592_-|WD40-repeat-domain-containing-protein
MRQFWHIFLFGSPLSELEYPEPENQRVKEVIRGFSAARLLVEGRRDTEGDPYVEPAHDALVWGWQKLLAWKQDKHQQENLVLQRQLAVVAMDWKNQQPENFYWDSNPQNWWQQLVKKDQQKGLLWSRNPRLAFLKQVLNSPTDNWLNKIEVEFVRKSLRHQVQNRISLLGVGILVSTGALFIGFNRWNQNQQNQIINLVEDSKRKFESNQQLEALVVALQAGKKIQLPVIADTKTKITVIQSLQSILYSIKEFNKFKKHSSTVTAMNYCNDGKTFASVSDFSTGTINLWGIDGKLIKSSQKLNTEVISAAFNRDCKKIVVGSRDGKIELRNIDGNLIKTFLGHKFDEVTSVSLNSDAKILASGTDKGIITLWNVENGKQFWSLQGHSKEENGEGNPKGSVVSIKFSPDGNLLASSGRWEGTIKLWSLDGKKIATIKDKNDRNRFSSFGFSPDGKLIVSGSRDGIVSVWKLDGKLVQKKKNDSKSFSGAMINTLEFTPDGKTIAFSDRDGNIKIWNLDDTEISTIKEHTSDVKSLSFSLDGKTLAGGTSNGNITVWNLVSGQPTIKFDRRHVKISFSPDNKSVAIGGFKFITFWSLDGKQLKKLEVPSSPPSLEHTNDVDSVSFSSDGKVLAAAANGIIQLWNVEKDELIWKIPSNGINSSSSYRSISFSPDGKTLATPVSSGELELLNLDGKTRLLLKGSYVHYGEEFSFSPDSKILAALSDKDNIIKLWSTQNGKELPSFTVDAEELHGVTFSPNGKVLAANSGGNIYIWNLETRKVLQTINSGRVNSISFNHDSKILISGGSDIKLWNIENGELFATLPFYASIVRYSPDGKILASINNGTVTLWNLDLEDLLRRGCSWGRDYLKHSPNVSASDRHLCDDVNPDFF
>NZ_CP046705.1|WP_114084687.1|54379_54790_+|hypothetical-protein
MKNNYVLLTLALLICTAAPQKALADEVWKTEEYKVVYQEDRNKTAVWRYGSDGVIFIDGLAGVFNDRGSYNGYWVQKSSSVRCDTYREGADGKPTYHWGRFKVTFIDSKFPSRWKADISLCDRDPVMTLNGTPVTQ
>NZ_CP046705.1|WP_114084678.1|53738_54308_+|TetR/AcrR-family-transcriptional-regulator
MPKETYIPYLIRLFRQFGYDGATLSKISEATGLGKASLYHHFPGGKDEMVETVLDFLQQWLAQNILTALTSQGDALTRLQRMCHRLSELYEGGHQPCMSAILLMGSARDIFHTRVNALFCIWINAIANVLIESGMDEELAKYRGEDAVIAIQGSLILSQGLNDPSPFMRVIQQLPRQLCTPKPGLQKDD
>NZ_CP046705.1|WP_094344691.1|52967_53585_-|glutathione-S-transferase
MIQLYGYELSGNSYKVKLMLSLLGLDYEWVKVDLPRGAHKQPEFLALNSFGQVPVLVDGNTILADAQAILVYLARQYGTEGWLPLEPEPMSRVIRWLSTTAGEVRLGPESARLYHLFKATDINLERVNQKSEFILTQLNNHLAEGEWLELGHPTIADVAVFPYIALANDGKISLEPYAHVQAWIERLKHLPGFIGMIGIEEPARV
>NZ_CP046705.1|WP_094344690.1|52361_52958_-|pyridoxamine-5'-phosphate-oxidase
MPRKFGEIAFTPEVEAAQSQRGSRQTYERYIANGPANDSITLEIAEFIAHLDGFYLGTVSSNGYPYIQFRGGAPGFLKVLNEKTLGFADFSGNVQYITVGNLEGEAKAFLFLMDYRQRRRIKVWGKAEYVEGDSALIERLRIPGYPAKVERAILFHVEALSENCSQHIPIRYSATEVEAMMAPLVARIEELEQKFVGE
>NZ_CP046705.1|WP_114084684.1|68342_69260_-|TniQ-family-protein
MSVESLANYESWDLTMNQLPKRSHLYSLKPIGFGTPTVESFTSYLQRLAAAHGVSIASLIRYKITPLFIQSNQPPDFLKADDAIKMLINAWHREPALLQQQSAKFWLDRTQHVEKLVAIVEKLTARLDLSFLTLLQWHSWRLNFSHIFHTEQRWCSGCYQDWREAGKPIYNPLLWTIEPVSVCPVHQRYLQLRCLYCGCFQQFLNLDCNSLGYCCVCNAWLGRFVDNTSFSQGSRFDWEKWAAQSVGQIFGAMPTLSLTSFSQVTPPAKYRRKPTLTKFLRWCYKLGINPVEGLEILSIIPSVVS
>NZ_CP046705.1|WP_114084685.1|69249_70365_-|AAA-family-ATPase
MAHDYSFPQELLTLPIADRISYFQQYTMAHPKLLIAAEKLKNAIDNPGFFSLIFLFGPTGVGKTTLLRRITQRLLASFHKEMELDKGFIPIANIEVATPEFSNFDWKDFYLRALGVLQDPCIQLPSYGRITNLKLKTSLEAALKHRRLKVFCLDEAQNLSKVASGRKLRDQTDCIKSLANLTQVKFVLAGTYDLLILRNLSAQLCRRSLDIHFERYKVENEEDLKAFRGVVQTFQRHLPFEEEPDLLKYWDFCYERSFGCVGILKDWLSQALATALLDGAKTLTLSHLKSSAYSHEQCMIIFNETRLGEKQLEFTPDSSALRIALGLESHHGSATHSTSQTTNTTNTKSRRSTTGNTKPQRRPVGGGENVG
>NZ_CP046705.1|WP_114084686.1|70364_72146_-|DDE-type-integrase/transposase/recombinase
MPLSVLYLIVPSYLAAAEIIKHATCEDIIEANRRYNLIQPYLEDALKAYPSSTIRRWRTQYQKALLIYGQGYLGLLPKHNNKGNRTPKIDSQTQEFMLDFIKEHYETPKQRRKIRVYESFVLACQTHDPPFKPPSRITFCHAIKQRSGHHQTRKRLGNRAAISEEPFYWELKQTTPRHGSRPFEIVHIDHTQIDIELVSSLESLTNCHIATNNSIHQNLGRPWATFMVDAYSRRILSVYLTFDEPSYRDCMMVIRICVARFGRFPQNIVVDNGKEFHSHYFEQLLASYTCTLKYRPPAHARFGSIVERLFGTANTQFIHELQGNTQIKRLHRKVTKSVSPERLAIWTLEELYSAFCEWAYSVYDQRLHPALGTSPCDAFVTGLATGGSRLHRRVAYDELFQILTLPAPDQRKRKVQPGKGVKIHNIYYWADVFRDPEIEKSMLWVRYDPWNAGIAYALAQGQWVKCISSYYQYFQGRSEKEIRLASAELNQRQRNYGRKLTINDRELVEFLNSKFAQEGAILKQRLRDTEHDKVHKIIQNNLITEPKLNLAEFAAEENNDCLGDDSTNEGKNCETISNLTAYITETLEYYGEF
>NZ_CP046705.1|WP_114081710.1|72232_73170_-|IS630-family-transposase
MSAPLRVRLTDLEDLTLLELRSATTVPQRTRERAHIIRLNAQGWNVPAIAKIFECHEHTVRATLRRWENKGLGGLWETSGRGAKCKWLEADLAYLEDCLEVEPRTYNSLQLSEKLAQDRNVQLSPSRLRRLLKKKWKWKRTRHTHKRKQDPEKRRIKQADLDTLKQAAVEGYVELKYLDESGCCRWSPVSYSYSRIGSQKQMAQVGSRGGRISILGLWQPQVSFEYALVQGGFKTKRYIEVMDWVAAKAQNTLVETGRISVIVHDNGSLHTSKKAKQKWLEWQEKGLFVFFLPPYCSEMNDRGRVASTKNS
>NZ_CP046705.1|WP_114081264.1|73198_74257_-|hypothetical-protein
MLDNLEFNNWCRQQDLSQAGQAIIEEIRSSNPSRRVTGARKNVCGSYPSRKMGCTIQFESHHNELARIYELEHDPCVLEYYDQPPAIELVYQSKSGRKNRHQYTPDFFIIRTDSAFWEECKTELELNKLNELNPNRYCKNSDGKWHCPPGEEYAHGHGLDFHVWSDALINWNFQQNLIWLLDYFGYSSEIIDETEQSLIVNTVNNHLGMTLTELLKNEEINPDVLYWLIATDKLYVELNKVKLSQPETVFVFINQNVALSYEHLNSIESTTQTSNQILLQIAVGTNIYWDGESWEIVNTGTTTTGLLRADGKLIELPNLAFTALIDTGKIVGDKTTQTSNIKISRWLQLNIR
>NZ_CP046705.1|WP_114081263.1|74643_75546_-|TniQ-family-protein
MPVENLKLYQSWELEQPILPERSRLFSLPPVGVGTAIVESLSSYLIRLADAHGITVGGLIRYYIAPLFFLNEQPPGLSKKDAIELVVVRLRKELAILQQPTAQFWLSQTQHVSKVVNVLEILTGRKDISYLTLLPWKTWRLSFNHIFHTQQRWCAGCYQDWRDANTPVYQPLLWALEPVTVCPYHQRYLQIYCLCYGHTQPFFQPQKLNGYCHECDAWLGRNLDLPSHSRSKGRKFDRDLWIAQALGNLLAATPSLHTNPLIRETKVTPKRTLPTLYKFLRWCYKLSLSPVEGLNLLEIQ
>NZ_CP046705.1|WP_147262468.1|75535_76018_-|hypothetical-protein
MFASRNSYKADNSEDLRAFQGIVQTFQRHLPLQIEPDLLKHWDFCYERCVGCIGILKDWLSRALFSALLKGDKTLTFSDLESHALKTEQCIILLNEALHGEEQLNSRRDTNALRAALGLEVATDVTPKTLQTSAKQTRRHAAVGQPLPQRRPVGGGHNAC
>NZ_CP046705.1|WP_114081250.1|76235_77075_-|tyrosine-type-recombinase/integrase
MRIIRQLLLWIVEHPGSGGDFQPEQLTKTAMEIYLAYLDTSGYSIAHQARVKSAVSGFARWLIEEKGILRRNPTRGLNIPAQPLLAPRQLTPDQRYILRNLIEKDGHPRSMAVFALGYWAGCRVSDVSWLRIEHTHIGPKVGWLHVGYKGGKARDIDLINAVRKPMYEYIHHGGRDTESDYTFTSQRNERLTEAGIHRWWKNIKAQATVSEWELIHDVTFHDLRHDFAHRAREAGWTLEEVAYYLGHITKKGTPAIQTTVRYTQSSRQQVKDKLALLKG
>NZ_CP046705.1|WP_114081251.1|77361_79008_+|DDE-type-integrase/transposase/recombinase
MPAEALTNLRHRLDMLPSRCQERRQLMEETASLYGVSIDTLYRALRNSSRPKSINRSDSGTPRKLSQAEMELYCEVIAATKIRTCNKKGRHVSTARAIELLEDFGMNTPQGFIKPPKGLLTKATVNRYLKTWGYDHLTMTRQPPAVRFQATHSNECWHFDLSPSDLKHVKQPLWVETGKGNPLLMLYSVVDDRSGVCYQEYHCVYGEDVTAALRFLFNAMTASTSDGCPFQGIPEMIYTDNGPIAKSHVFQNVMDCLGIKLASHLPAGKDGRRVTARSKGKVERPFRTVKEAHETLYHFHEPENEVEANLWLRQYLLNYNDQKHRTEAHSRLEDWLRNLPKSGIRQMCSWERFCTFAREPQRRKVDATARVSVEGVAYEVNPDLAGETVVLWWGLFDNELYVEKGDQRYGPFYPVDGPIPLHRYRKHKKTKTEERADRIADLALKLGLPRTALDKNADLQFLVDKYKEIEPTVTPFKDPDPFQEFTYPTVLFAKLAISDYLAKPLAKLSTEQIAFIDGLLAETLNKKVIIERVRQYFHSNKGGQQNAH
>NZ_CP046705.1|WP_114081249.1|78997_79969_+|AAA-family-ATPase
MLTEVMEHFRLVKEFPKAGYYETDHQKQMFKDIKAAIHSGKLIAITGIIGCGKTTTLRRLFDVLEKEGKILVSKSLSVDKERATLPTLIAALFYDLSTDKEIKIPKDGEKRERELRDLIRKGKKSVALFVDEAHDLHYSTLTGLKRLIEVVEDGGGTLSVVLAGHPKLKNDLRRPTMEEIGYRATVFSLEGIVGNQREYIEWLVSECTISDTPIGEILEAEAIELLATRLLTPLQIEQHLTLALEAAYRVAVKPVTTVIVESVLSKQIDDLEPTLTRHGYDVRGLAEQFNAKPAEIKSLFRGQLDPTRARELQEQMLAAGLPL

Crispr_ID: NZ_CP046705_2

• CRISPR_ID: NZ_CP046705_2
• CRISPR_location: 152918-153020
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP046705_2

Consensus_repeat	Method
ATAGCCCCCACATAGCCACCATG	CRISPRCasFinder

spacers of NZ_CP046705_2

>2.1|152941|57|NZ_CP046705|CRISPRCasFinder
TAGCCACCATGTGGGAGTCAAATTTTGCTCAAGCCTCTAAACTGCTTTGGGGTACAT

CRISPR arrays and Neighbor proteins around NZ_CP046705_2

CRISPR arrays

The CRISPR arrays of NZ_CP046705_2

>merge|NZ_CP046705|2|152918-153020|CRISPRCasFinder
ATGTACCCCACATAGCCCCCACATAGCCACCATGTGGGAGTCAAATTTTGCTCAAGCCTCTAAACTGCTTTGGGGTACATATAGCCCCCACATAGCCCCCATG

>NZ_CP046705|2|2|152918-153020|CRISPRCasFinder
ATGTACCCCACATAGCCCCCACA	TAGCCACCATGTGGGAGTCAAATTTTGCTCAAGCCTCTAAACTGCTTTGGGGTACAT
ATAGCCCCCACATAGCCCCCATG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046705.1|WP_159402649.1|158186_160145_+|ATP-binding-domain-containing-protein	unknown	unknown	gnl|CDD|273632
NZ_CP046705.1|WP_114086244.1|142623_143133_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046705.1|WP_114086245.1|141904_142711_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046705.1|WP_114081708.1|161823_162324_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379267
NZ_CP046705.1|WP_114081709.1|161263_161833_-|IS630-family-transposase	unknown	unknown	gnl|CDD|315923
NZ_CP046705.1|WP_109012817.1|150220_150823_+|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	unknown	unknown	gnl|CDD|367091
NZ_CP046705.1|WP_114081388.1|160234_161185_+|RpoD/SigA-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|274382
NZ_CP046705.1|WP_114086242.1|149739_150219_+|SocA-family-protein	unknown	unknown	gnl|CDD|379096
NZ_CP046705.1|WP_114086248.1|151503_151794_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046705.1|WP_114086246.1|141343_141778_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046705.1|WP_159402648.1|155634_155805_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046705.1|WP_114086240.1|153870_154971_-|hypothetical-protein	unknown	unknown	gnl|CDD|379519
NZ_CP046705.1|WP_114086238.1|156092_156884_+|ParA-family-protein	unknown	unknown	gnl|CDD|224113
NZ_CP046705.1|WP_159402647.1|155276_155543_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046705.1|WP_114086243.1|144128_148916_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046705.1|WP_114080956.1|162414_162921_-|DUF1993-domain-containing-protein	unknown	unknown	gnl|CDD|370447
NZ_CP046705.1|WP_114086237.1|156886_158005_+|ParB-N-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|275105
NZ_CP046705.1|WP_114086249.1|143550_144054_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046705.1|WP_109012819.1|149212_149473_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046705.1|WP_114086241.1|151799_152759_-|ParM/StbA-family-protein	unknown	unknown	gnl|CDD|212669

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046705.1|WP_114086238.1|156092_156884_+|ParA-family-protein	gnl|CDD|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	4.10226e-45
NZ_CP046705.1|WP_114081388.1|160234_161185_+|RpoD/SigA-family-RNA-polymerase-sigma-factor	gnl|CDD|274382	TIGR02997, RNA_polymerase_sigma_subunit_sigma70/sigma32, RNA polymerase sigma factor, cyanobacterial RpoD-like family. This family includes a number of closely related sigma-70 (TIGR02937) factors in the cyanobacteria. All appear most closely related to the essential sigma-70 factor RpoD, and some score above trusted to the RpoD C-terminal domain model (TIGR02393).	5.89997e-151
NZ_CP046705.1|WP_114081709.1|161263_161833_-|IS630-family-transposase	gnl|CDD|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.77977e-22
NZ_CP046705.1|WP_114081708.1|161823_162324_-|helix-turn-helix-domain-containing-protein	gnl|CDD|379267	pfam13565, HTH_32, Homeodomain-like domain.	1.12024e-08
NZ_CP046705.1|WP_109012817.1|150220_150823_+|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	gnl|CDD|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	1.64259e-09
NZ_CP046705.1|WP_159402649.1|158186_160145_+|ATP-binding-domain-containing-protein	gnl|CDD|273632	TIGR01448, recD_rel, helicase, putative, RecD/TraA family. This model describes a family similar to RecD, the exodeoxyribonuclease V alpha chain of TIGR01447. Members of this family, however, are not found in a context of RecB and RecC and are longer by about 200 amino acids at the amino end. Chlamydia muridarum has both a member of this family and a RecD. [Unknown function, Enzymes of unknown specificity].	4.46568e-79
NZ_CP046705.1|WP_114086242.1|149739_150219_+|SocA-family-protein	gnl|CDD|379096	pfam13274, DUF4065, Protein of unknown function (DUF4065). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea and viruses. Proteins in this family are typically between 155 and 202 amino acids in length.	9.20107e-06
NZ_CP046705.1|WP_114080956.1|162414_162921_-|DUF1993-domain-containing-protein	gnl|CDD|370447	pfam09351, DUF1993, Domain of unknown function (DUF1993). This family of proteins are functionally uncharacterized.	5.89815e-91
NZ_CP046705.1|WP_114086237.1|156886_158005_+|ParB-N-terminal-domain-containing-protein	gnl|CDD|275105	TIGR04285, parB-like_partition_protein, nucleoid occlusion protein. This model describes nucleoid occlusion protein, a close homolog to ParB chromosome partitioning proteins including Spo0J in Bacillus subtilis. Its gene often is located near the gene for the Spo0J ortholog. This protein bind a specific DNA sequence and blocks cytokinesis from happening until chromosome segregation is complete.	2.00867e-17
NZ_CP046705.1|WP_114086241.1|151799_152759_-|ParM/StbA-family-protein	gnl|CDD|212669	cd10227, ParM_like, Plasmid segregation protein ParM and similar proteins. ParM is a plasmid-encoded bacterial homolog of actin, which polymerizes into filaments similar to F-actin, and plays a vital role in plasmid segregation. ParM filaments segregate plasmids paired at midcell into the individual daughter cells. This subfamily also contains Thermoplasma acidophilum Ta0583, an active ATPase at physiological temperatures, which has a propensity to form filaments.	2.29473e-33
NZ_CP046705.1|WP_114086240.1|153870_154971_-|hypothetical-protein	gnl|CDD|379519	pfam14239, RRXRR, RRXRR protein. This domain is found in bacteria, eukaryotes and viruses, and is approximately 180 amino acids in length. It contains a conserved RRXRR motif. It is often found in association with pfam01844.	6.25077e-58

Protein sequences

>NZ_CP046705.1|WP_114086241.1|151799_152759_-|ParM/StbA-family-protein
MSNIHTLQKIFPAGFDNGYGSLKLLVDGFEVVRVPSYITNAEMEDVPGRVVFNGSAYTVGESAFRTGNYFDRNTDNNENKVNNALLTLFGALAHLPHRKAWHLKLVVSLHDVALAEELQKVLNGEYQPILAGKQSEVKIEVLKVVLEGMGALFGHQLPKKLTILDFGNGTTLYSRYNQGKREVHTAYPTGVEVLINDISQKMKHLNGGKIGDASKIRFCLEMGHTRYSRDIDIKDVYSACLKDWYEKYLKKVVNLTLDAKHQGDEIWAIGGGCLLPGFKKLLEKNGFKILDNPVEANVFGLLEMAKAISSKNSPTTSIK
>NZ_CP046705.1|WP_114086248.1|151503_151794_-|hypothetical-protein
MTEKLDLAPIKIRLKENYRERIFAESQQLGKSYLETLYFIIDCYFVFIKAGLATQQVAFTPITTDENKLPSMTSTPFAQEKEEDSEPETFSLDFDL
>NZ_CP046705.1|WP_109012817.1|150220_150823_+|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin
MAGKRPRQGWIYSTNPYRVSLRCKLGHIHIYNLDEPAEVECQTCSENINSSRVFRGTHPYIIWTSDQFQDESGYIATFSVIPLTSQTTFNGLPTTYPINSTSRNGLDKNSYALVHQICTVDANCFKGSSANWLERIGQLDKADREAIEERLKYFLSIQENPSEDWFAQNASPELLKKIFDYLPEDTKNLVIEELINNLDS
>NZ_CP046705.1|WP_114086242.1|149739_150219_+|SocA-family-protein
MLDKLIKYFVYATKGYITKTQLIKFLYLADLYSVKWTGKQLTDLDWCYYQFGPWNEGIDTALNQMNGKEIVQESQYNATYIRPVNQAAHADDLDIPLSIKFVLDNIRREWAGSEKLNQLLEYVYSTAPMVEAKNTHRPEEKVKLNLQAEREKLVSELGL
>NZ_CP046705.1|WP_109012819.1|149212_149473_+|hypothetical-protein
MHELIACGFYKKTTPNGKKVFDKNALALAPLKEVRHKLSLLSEYPNRAARFKVPALWVDAWCQRCFVSFTEMVKWRRVIQRDATSP
>NZ_CP046705.1|WP_114086243.1|144128_148916_+|hypothetical-protein
MTLELKHFDPRLNQWIYTDDNKTNSQSILTEKLNNTLLEFYFPDKEFSFGHSDEYSTAEELKNHPNGQILLLSSKTRLLYGDKECLEVIQKICPDSKDRGAYGSIFLGACKNAIHEKLNILVVDDSTEKAGENGGILSNDLAYKLVGDCYGQISTQLYDKVTLRESQPDKSYRVIQHRFGWVDGVGEDTTKYRFGKGTLRPYRLDEIKYADPNNKPKIDIILPVSSFKGTDKDRPKGPTKPQIQPGLYQQNIWLAEKGQSQQGQMSISQLLASFPQGIKDFAEELEVQAQRLASIQDNPRNVAAYYCERYEKRKESLSQNKLKTSDIINQETDVKNLGTNDDLDADHELDDESAKDDLFMYKLIKADLLGHQQLLETEKVKQELSRFVQSEWRDIAVGKTLTFDRGMIIPSKELKNGEICVPWLKLGEKVLNFRSPFLNSNGLCVSTNKHVEDSVAPDGKSLQGIIVVNDEDHKRILARIEALETQGIEHNEVNPLETESERQARDYDGDCIGVAKASLYPNLTAEAERRNLPQNAYSPTVKLKKQSFYLEDGSQPPFEKIAIHMSDSISVGIINNQVTALEALESEIEVLKTYGTFEQKSNYLDQVSNHYETLFEQERQKDPKLIREEYKPYMQGVVEIAHCQRTPEIIQQAMDINRQMYRSMIEEGCYQNQIAVDLFKSAKKPEMNLIRENNRYLYRDVNYIKDKKSSSVYLSTGITPKGYSPVELLINQTNKYFQESQLESRPIVQFKDLFKGVEFTPQQKFAAIAAKYEFDQKFNAAVRASRRRETESGPSAIVQTDSGTQLEITNLTRYGHPLIWKAQTLSIHLDEIKFTNSERPHKLLAVAQIDGEIGEDGKPAYRNLGTVSQQSQADYNLKAGMTIQGAKLLELKPELTRSQTKLLFALAQETAEAFYAKIPESEKLTGAAAAWNICASRQDELEVARKENANPQAIAKKVSNFAFAAFPNEIISRLDKLQFTEPKLVTLNNEANQFLGRDWNAHEKHPIEIRASHHPVGHERHVSRLMFVQDADGEYKEFAMLETRTAQLPIGTKALSCMVGIDPATASATIGLPGNEPIEITIRELKNFSYAGLVFNAESVNLEFGTVPIPDKTVKIKIDALTLGELDSDSAQQLKEINYLKNGNPLKLKLTSISETGDQAFVLGESPNGNFLKINKINFYDFSGQTFNDQDYRKLTIETSASKTRDAVFLNGEPLGVLHFKKDKDALRQLGLLKTGQLTLAPAIIESNFSVICAQINPNTVEYPQKWTKEFQAFGTQSVNPQQQEMIESSAKILHHIKERPTFLFSTESNKKLGVMGLAVDNQKAETVTKWLTAQKVEWQQVPIEDVIRETKKGLAVFNLVDSSIPAKTLESMAKKFGAVIETDSEYQQRVNSLATRPQFLKPPEQTAQSPPNQSTLLLSTTPFTSDISNGAKTEPLSVEKLPTVTIDDLRNWYNAADKLGKPEDYKKRIVEVAYGFKAGEQLSAQALTVMNQDKFELEAISRLTQIAQRIGMVWGKSDENGIQVQGKIYDLAFNTQQRDLTISQKNGEVILNLQSGQVQTNKLTPQILQTFEDANSQIDKILAKNKSQELEIQR
>NZ_CP046705.1|WP_114086249.1|143550_144054_-|hypothetical-protein
MHKKEFHPDGSLKNEARQEMLSVGMSNEAIDDYASRLKARYDEWKHLDETDPEPWPIYTAYDFFTEQEKKEFNPDGSLRPEYVEYARQIGISESALEQLEWRKKIEVDDYNEMSANHVEQGINFGEWLMQGRIGNSRTYVQRRQQMEQDLHNFEDVDSLPFDKDTSY
>NZ_CP046705.1|WP_114086244.1|142623_143133_+|hypothetical-protein
MYFEGANPTATAALEQFAAELREWFDFRLEQERQTIEIQALKASDAKATRLAAHKLENLQAWNEAQESRKKLRKQRSEKFKSNLFWFGQWIGSGRSGIFFFICGVLISTTATAVAIINLPTFLSCPNSKSLCYQVYQMRFNNKSVILPGQAKDIVAEYERNKTKSKRRK
>NZ_CP046705.1|WP_114086245.1|141904_142711_+|hypothetical-protein
MYQPQELFNELSTSEISRTLRLSGISEKELYTEDDADRFRECRTLIEQGGTDEDVMALLSPVVDVVLSETPDNSLAEIKNGRKKSGKKATKSLDITELLSLAREQGFKLTLTTALKIFADCGLKEQDEYTSEESERFLAACNLRHQGKTEIEIAANFGAGVLDAADIELSLEETERLIQDSGDLLFGEMLREKAGQHAAIAPGLYLKYLAQELASESSQQNWRSLLEMIKARAVGKPQPQFTLKVQTLQLQQPLNSLPPNSENGSTSD
>NZ_CP046705.1|WP_114086246.1|141343_141778_+|hypothetical-protein
MFSDVEFRLRSRVKADSSEAVVIKYLNSKNTLYPARDMAMIAISSYWLPLAYQAMDQSVDLEQHIRACLYRLQLHSSYLMGLLGEIPSQGTPMIAVASNQSQPLQLIQSEPLAISRTLVKEALQIARTPVPEELESETDWLNPF
>NZ_CP046705.1|WP_114086240.1|153870_154971_-|hypothetical-protein
MRVSVLNPDGSPAMPTKPSRARRWLKAGKAKVVHNDLNLFCVQLICEPSGYEVQDIALGIDPGKMFTGIGVQSSRFTLFTAHLILPLQAITKKMNGRRILRRARRARRINRKVAFHLRAHRQKRFSNRRQGKLPPSIRANRQMELRVTKELIKHFPVSDIRYEVVKARTEKGKGRGFSPVMVGQKFMFQWLEELCPTVSQEGWQTSTLRRQLGLAKDKGDKSKQIPETHANDGIALAASHFMSYQSFQSSNGRGHHWQGQVTVTKSVFRVISRPNLYRRQLHFENPVSGVTGNRKRKGGTITPFGFRSGDLVRAKKSGKTVLGWIGGYSEATKVVSVYDINWRRYGQFKASKVELLQRSTRLCVSR
>NZ_CP046705.1|WP_159402647.1|155276_155543_+|hypothetical-protein
MSAVASYCSTVVVLQLVSVSAVSAVIIEGKNFICIINRKYLSPITLEEGVCHHSCQGKGIAVVESTSLACSLIAVCSQLGHFTFVKIT
>NZ_CP046705.1|WP_159402648.1|155634_155805_-|hypothetical-protein
MKPPKVEPQVTGKRNKKKIDSPPATKPHIPFQDRPEEPELPPEPCQHCNSWIATRR
>NZ_CP046705.1|WP_114086238.1|156092_156884_+|ParA-family-protein
MKQIVLSLIANAGGVGKTTLSVHLAYEIVRRGFSVAILDLDPQRSLDVFCGIPPAEVSNTLVKALSKDFKGDWKLISVWEESKIQVCQGHPLMAEMANELVIRKRGEYTLSDRLKNYPLPHNLVILDCPATLGMLNVNALAASTHILVPVQLEMKAISGSAELVEWCISTSDELQLSPRPPILGFVPSMYDDTVAMHRQYLEQLPEITEHLQLKLYPKVRSSNEFKNASAHGLPLQKYRPKHPACKDFKQITDDLVALIKEKK
>NZ_CP046705.1|WP_114086237.1|156886_158005_+|ParB-N-terminal-domain-containing-protein
MALPKIASRFSSAVQKTEQEQKIAELQIEIERLRTAQSPELENELQKLREQLQNQSGEVQVDLNLIDPNPNQPRQTITPELIQAKARLLKKHGQISAVILVRQSNGRYILLDGQLRTEGAKLLGWSTIRAVIVAMPNDLDQSALLTFLGFEDLNPLDKAEAVFKEVMKSANLSMDEVSTMLGTVIKRIERNGNSKELAKLMAVSVDEQQQGLELLEITGKEQSLLLVLLELGLNPSSVKANLMPMLYLPEDLKQVIRQHGLKGAHALALATLSAKALDISENQAASERIAATDEVLKKNLTVTETRELVRKIKIKYLKSNEQELKEVKIIFQKVNGISGDLLKKASSKQLHEMRSLFQEKLQEIDKVIATSK
>NZ_CP046705.1|WP_159402649.1|158186_160145_+|ATP-binding-domain-containing-protein
MSTPPNLSPQQVSAFPQHETITGVVERLTFYSAESGYTVARLTRPRSNELTTIVGSFANIQPGQTLQLIGFWRDHPQFGPQFQVINYQETKPATLTGIEKYLGSGLIKGVGPVTAKRIVAHFGLETLDIIENQIERLIEVQGIAKKRITLIKNAWSTQKAIKEVMVFLQGHGVSTTYAVKIYKQYKDEAIATVTKNPYQLAADIYGIGFLTADKIARNIGIAPDSEFRDRAGIVHCLSEAAEDGHCYLPQSELIDSVIKLLTTESHQSTEEAVAIIIKDMALAEELIREWDEEKRLLCYKPTYFHTEQNLAQLIRQRLENPVGTDIERVRDWIDRFTASRKIQLSQQQRQAVETAAYSKIMILTGGPGVGKTFTTHTIVTVGPGQILADLINSGCVPVVRLTQVFRQAQTSAIITAAHQINRGQYPTIEPISDNPVSDCIWHGGGHQPEHGVQAICELITDLLPRLGFNPATDVQVLCPMTRGVVGTRNLNTVLQQLINPPSPSKVEINRGGNLLREGDRIIQLTNDYNREVFNGDLGIILTIDTVEQEVTVQYGERTVVYDYADLNEIALAWSISIHKSQGSEYPVIVLLIYMQHYMMLTRNLFYTGITRAKKLAIVVGAKKAISLAVRSTDDQRRYTRLQQRLLHPGLHW
>NZ_CP046705.1|WP_114081388.1|160234_161185_+|RpoD/SigA-family-RNA-polymerase-sigma-factor
MSSLSSDMVRIYLQEIGKYPLLKPDEEIAYARLVQEMIAIEQSKNELTQQLEREPTMTELANTVEKTETQVRSALHLGQKAKQKMVTANLRLVVSVAKKYQNRNLEFLDLIQEGAIGLQRGIEKFDPNLGYKLSTYAYWWISQAITRAIAEQSRTIRLPVHLTEILNKIKKVQRESFLKLGRHATAEEIATSLNISPDKLREYLSASRTAISLNKKIGDEQETELGEILTDVGVSPEKLLTQELLSQDVAKFLEPLTPIQRQVLTLSFGLENDQHFNLAQIGQQLNLSRERIRQIQVKAISILRHRQSDMQEYLID
>NZ_CP046705.1|WP_114081709.1|161263_161833_-|IS630-family-transposase
MILNCLEKHLAPGKCVRYLCQDETRVGLKTLTGKVITASGVKPTVEVKWPRENFWIYGAIEPLTGDHFLYEYPKLNGECFQQFLDWLSQQLGGDYAILQVDQAPAHTSSAIRWPENIIPLFQPPSAPELNPIERLWQLLKKPLKNQLFSSLQNLRDRIQEIFNQLTLEQVISISSYNFILEALFYAASY
>NZ_CP046705.1|WP_114081708.1|161823_162324_-|helix-turn-helix-domain-containing-protein
MSRPFEIEIAESEEELKKRLQTANLGNQKEKLIMLWWIKSGQAKEQQDIGKRLAKDTSTVTRWLQKYRSGGLDELLKIKKAPGAKRKIPEGAITALEEELKTGKGFSSYGAIVEWLKQEQGLDIEYATVYALVRYRLGAKLKVPRPQSHKQDEKLVSEFKKNSVSF
>NZ_CP046705.1|WP_114080956.1|162414_162921_-|DUF1993-domain-containing-protein
MTISMYQALIPVSIRTLNNLINILEKGAAYAETKKIDPSVLINSRLSPDMFPLSKQVQIASDIANRGAARLAGIEPPKFEDNETTFGQLIDRIQKTISHLNTFKPEQIDGSEEREITLQMRDNTLCFQGMPFLLYFVLPNLYFHVTTAYDILRHCGVELGKGDFLGQP

Crispr_ID: NZ_CP046705_3

• CRISPR_ID: NZ_CP046705_3
• CRISPR_location: 218622-218707
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP046705_3

Consensus_repeat	Method
TTTGCAATTAATGTGAGCCAAGTC	CRISPRCasFinder

spacers of NZ_CP046705_3

>3.1|218646|38|NZ_CP046705|CRISPRCasFinder
GGATGATTGCAAGCCCATTGCAAATAATAATGAGTCTG

CRISPR arrays and Neighbor proteins around NZ_CP046705_3

CRISPR arrays

The CRISPR arrays of NZ_CP046705_3

>merge|NZ_CP046705|3|218622-218707|CRISPRCasFinder
TTTGCAATTAATGTGAGCCAAGTCGGATGATTGCAAGCCCATTGCAAATAATAATGAGTCTGTTTGCAATTAATGTGAGCCGAAGT

>NZ_CP046705|3|3|218622-218707|CRISPRCasFinder
TTTGCAATTAATGTGAGCCAAGTC	GGATGATTGCAAGCCCATTGCAAATAATAATGAGTCTG
TTTGCAATTAATGTGAGCCGAAGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046705.1|WP_114080950.1|214028_214445_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046705.1|WP_114081255.1|221088_221574_+|bleomycin-resistance-protein	unknown	unknown	gnl|CDD|319906
NZ_CP046705.1|WP_167756041.1|221880_223113_-|hypothetical-protein	unknown	unknown	gnl|CDD|214619
NZ_CP046705.1|WP_114081252.1|220646_220838_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046705.1|WP_159402652.1|218771_218924_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046705.1|WP_114080756.1|224034_224541_-|translation-initiation-factor-IF-3	unknown	unknown	gnl|CDD|234582
NZ_CP046705.1|WP_159402653.1|220936_221077_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046705.1|WP_159402651.1|212006_212267_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046705.1|WP_114080945.1|207828_208431_-|IS630-family-transposase	unknown	unknown	gnl|CDD|315923
NZ_CP046705.1|WP_114080946.1|208974_210297_-|MATE-family-efflux-transporter	unknown	unknown	gnl|CDD|240541
NZ_CP046705.1|WP_114081250.1|217710_218550_+|tyrosine-type-recombinase/integrase	unknown	unknown	gnl|CDD|274042
NZ_CP046705.1|WP_114081253.1|219582_220071_-|TIGR00725-family-protein	unknown	unknown	gnl|CDD|375733
NZ_CP046705.1|WP_114081251.1|215777_217424_-|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl|CDD|366234
NZ_CP046705.1|WP_114081249.1|214816_215788_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|225806
NZ_CP046705.1|WP_114080757.1|223196_223445_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046705.1|WP_114080949.1|212684_213635_-|RpoD/SigA-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|274382
NZ_CP046705.1|WP_114080947.1|210599_211124_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046705.1|WP_114081254.1|218966_219419_-|DUF1392-family-protein	unknown	unknown	gnl|CDD|284550
NZ_CP046705.1|WP_114080951.1|211251_211971_-|NAD(+)--rifampin-ADP-ribosyltransferase	unknown	unknown	gnl|CDD|378815
NZ_CP046705.1|WP_084227073.1|220195_220471_-|UBP-type-zinc-finger-domain-containing-protein	unknown	unknown	gnl|CDD|366940

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046705.1|WP_167756041.1|221880_223113_-|hypothetical-protein	gnl|CDD|214619	smart00325, RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases. Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains. Improved coverage.	0.000224984
NZ_CP046705.1|WP_114081255.1|221088_221574_+|bleomycin-resistance-protein	gnl|CDD|319906	cd07242, VOC_BsYqjT, vicinal oxygen chelate (VOC) family protein similar to Bacillus subtilis YqjT. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	6.81801e-12
NZ_CP046705.1|WP_114080756.1|224034_224541_-|translation-initiation-factor-IF-3	gnl|CDD|234582	PRK00028, infC, translation initiation factor IF-3; Reviewed.	1.29137e-59
NZ_CP046705.1|WP_114080946.1|208974_210297_-|MATE-family-efflux-transporter	gnl|CDD|240541	cd13136, MATE_DinF_like, DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Escherichia coli DinF is a membrane protein that has been found to protect cells against oxidative stress and bile salts. The expression of DinF is regulated as part of the SOS system. It may act by detoxifying oxidizing molecules that have the potential to damage DNA. Some member of this family have been reported to enhance the virulence of plant pathogenic bacteria by enhancing their ability to grow in the presence of toxic compounds. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	4.16925e-113
NZ_CP046705.1|WP_114080945.1|207828_208431_-|IS630-family-transposase	gnl|CDD|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.47182e-44
NZ_CP046705.1|WP_114081250.1|217710_218550_+|tyrosine-type-recombinase/integrase	gnl|CDD|274042	TIGR02224, Tyrosine_recombinase_XerC, tyrosine recombinase XerC. The phage integrase family describes a number of recombinases with tyrosine active sites that transiently bind covalently to DNA. Many are associated with mobile DNA elements, including phage, transposons, and phase variation loci. This model represents XerC, one of two closely related chromosomal proteins along with XerD (TIGR02225). XerC and XerD are site-specific recombinases which help resolve chromosome dimers to monomers for cell division after DNA replication. In species with a large chromosome and homologs of XerC on other replicons, the chomosomal copy was preferred for building this model. This model does not detect all XerC, as some apparent XerC examples score in the gray zone between trusted (450) and noise (410) cutoffs, along with some XerD examples. XerC and XerD interact with cell division protein FtsK. [DNA metabolism, DNA replication, recombination, and repair].	5.07702e-21
NZ_CP046705.1|WP_114081253.1|219582_220071_-|TIGR00725-family-protein	gnl|CDD|375733	pfam18306, LDcluster4, SLOG cluster4 family. Family in the SLOG superfamily, observed as a standalone domain with little informative genome context, although related families in the SLOG superfamily are predicted to function in diverse conflict contexts.	6.60801e-59
NZ_CP046705.1|WP_114081251.1|215777_217424_-|DDE-type-integrase/transposase/recombinase	gnl|CDD|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	1.79386e-07
NZ_CP046705.1|WP_114081249.1|214816_215788_-|AAA-family-ATPase	gnl|CDD|225806	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion].	2.06497e-48
NZ_CP046705.1|WP_114080949.1|212684_213635_-|RpoD/SigA-family-RNA-polymerase-sigma-factor	gnl|CDD|274382	TIGR02997, RNA_polymerase_sigma_subunit_sigma70/sigma32, RNA polymerase sigma factor, cyanobacterial RpoD-like family. This family includes a number of closely related sigma-70 (TIGR02937) factors in the cyanobacteria. All appear most closely related to the essential sigma-70 factor RpoD, and some score above trusted to the RpoD C-terminal domain model (TIGR02393).	1.99888e-151
NZ_CP046705.1|WP_114081254.1|218966_219419_-|DUF1392-family-protein	gnl|CDD|284550	pfam07154, DUF1392, Protein of unknown function (DUF1392). This family consists of several hypothetical cyanobacterial proteins of around 150 residues in length which seem to be specific to Anabaena species. The function of this family is unknown.	1.61743e-75
NZ_CP046705.1|WP_114080951.1|211251_211971_-|NAD(+)--rifampin-ADP-ribosyltransferase	gnl|CDD|378815	pfam12120, Arr-ms, Rifampin ADP-ribosyl transferase. This protein is found in bacteria. Proteins in this family are typically between 136 to 150 amino acids in length. The opportunistic pathogen Mycobacterium smegmatis is resistant to rifampin because of the presence of a chromosomally encoded rifampin ADP-ribosyltransferase (Arr-ms). Arr-ms is a small enzyme whose activity thus renders rifamycin antibiotics ineffective.	5.0296e-67
NZ_CP046705.1|WP_084227073.1|220195_220471_-|UBP-type-zinc-finger-domain-containing-protein	gnl|CDD|366940	pfam02148, zf-UBP, Zn-finger in ubiquitin-hydrolases and other protein.	1.04044e-06

Protein sequences

>NZ_CP046705.1|WP_114081250.1|217710_218550_+|tyrosine-type-recombinase/integrase
MRIIRQLLLWIVEHPGSGGDFQPEQLTKTAMEIYLAYLDTSGYSIAHQARVKSAVSGFARWLIEEKGILRRNPTRGLNIPAQPLLAPRQLTPDQRYILRNLIEKDGHPRSMAVFALGYWAGCRVSDVSWLRIEHTHIGPKVGWLHVGYKGGKARDIDLINAVRKPMYEYIHHGGRDTESDYTFTSQRNERLTEAGIHRWWKNIKAQATVSEWELIHDVTFHDLRHDFAHRAREAGWTLEEVAYYLGHITKKGTPAIQTTVRYTQSSRQQVKDKLALLKG
>NZ_CP046705.1|WP_114081251.1|215777_217424_-|DDE-type-integrase/transposase/recombinase
MPAEALTNLRHRLDMLPSRCQERRQLMEETASLYGVSIDTLYRALRNSSRPKSINRSDSGTPRKLSQAEMELYCEVIAATKIRTCNKKGRHVSTARAIELLEDFGMNTPQGFIKPPKGLLTKATVNRYLKTWGYDHLTMTRQPPAVRFQATHSNECWHFDLSPSDLKHVKQPLWVETGKGNPLLMLYSVVDDRSGVCYQEYHCVYGEDVTAALRFLFNAMTASTSDGCPFQGIPEMIYTDNGPIAKSHVFQNVMDCLGIKLASHLPAGKDGRRVTARSKGKVERPFRTVKEAHETLYHFHEPENEVEANLWLRQYLLNYNDQKHRTEAHSRLEDWLRNLPKSGIRQMCSWERFCTFAREPQRRKVDATARVSVEGVAYEVNPDLAGETVVLWWGLFDNELYVEKGDQRYGPFYPVDGPIPLHRYRKHKKTKTEERADRIADLALKLGLPRTALDKNADLQFLVDKYKEIEPTVTPFKDPDPFQEFTYPTVLFAKLAISDYLAKPLAKLSTEQIAFIDGLLAETLNKKVIIERVRQYFHSNKGGQQNAH
>NZ_CP046705.1|WP_114081249.1|214816_215788_-|AAA-family-ATPase
MLTEVMEHFRLVKEFPKAGYYETDHQKQMFKDIKAAIHSGKLIAITGIIGCGKTTTLRRLFDVLEKEGKILVSKSLSVDKERATLPTLIAALFYDLSTDKEIKIPKDGEKRERELRDLIRKGKKSVALFVDEAHDLHYSTLTGLKRLIEVVEDGGGTLSVVLAGHPKLKNDLRRPTMEEIGYRATVFSLEGIVGNQREYIEWLVSECTISDTPIGEILEAEAIELLATRLLTPLQIEQHLTLALEAAYRVAVKPVTTVIVESVLSKQIDDLEPTLTRHGYDVRGLAEQFNAKPAEIKSLFRGQLDPTRARELQEQMLAAGLPL
>NZ_CP046705.1|WP_114080950.1|214028_214445_-|hypothetical-protein
MKGWVNDPHSGGVKIPEQVKQRTKHRILAYAEQHYAGKYIRIDVRFKGYFCYIDAYKEPFLPDNDDLSMFKITRSEYIERAKNTPIHLCRLRYKGNEEKWTKAFYTYSNEKYEPSVFNNGTFYGTPEEAFQSSALYLD
>NZ_CP046705.1|WP_114080949.1|212684_213635_-|RpoD/SigA-family-RNA-polymerase-sigma-factor
MPSPTTDLVHSYLKEIGRYPLLTPEQEITNARLVQQMMAIEEQRASLAVQLNREPTTRELATSLGQTEAEVQSIIQQGQKAKEKMVTANLRLVVSVAKKYQNHNLDFLDLLQEGALGLQKGIEKFDPNRGYKLSTYVYWWIKQSITRAIGEKSRTIRLPIHINEKLNKIRRVQQQLSQSLGRPPVVAEIAESLNLLPNQIREYLHVSRAPVSLEMRVGDERETELADILPMDGISLDEQIAQELLHQDLSKLLALLNPRQREVLTLRFGLEDNQQLTLSQVAKRLNLSRETIRKSEHLALKILRSHQNKIKDYLLN
>NZ_CP046705.1|WP_159402651.1|212006_212267_-|hypothetical-protein
MPSATSTQEISSPYRQEETQSYDLQEWEGYSWVIFRFEVRAIPSLLLSETLREREATPFLRNALAFGTPLTNTKLVGFAAKVITIP
>NZ_CP046705.1|WP_114080951.1|211251_211971_-|NAD(+)--rifampin-ADP-ribosyltransferase
MAGFNDLSSQQFYHGTKADLKLGDLIESCNPPDVGERDRMATYVYLTPNLDAAIWGAELALGEGHGKVYIVEPLGQIENVPELTKQKSPKHLSMSYRSREPLWVTGTVTELTLYHGTRADLKPGDLIEPGYHSNYGQRKKATYVYLAATFDAATWGAELALGEGRGRIYIVEPIGPIEDDPNVTDKKFPGNPTKSYRSREPLRVMGEVMDWQGHSPEAIKTMKDNLERLKQLGIEAIED
>NZ_CP046705.1|WP_114080947.1|210599_211124_+|hypothetical-protein
MSMISFRPMILIIGISIGLLPLLSNWQVLAQNQSQNIELKVYSENEQKQSCPDKVIVTEKPHPYQEGSFSTDGSVNLSAYASNISVQASNSFSVTWVGTLKPRYSKCFASAGMTKVDGQAYSEHLNYLRMHFVKGKVYFILDLAGGSDPNNYPLVVLNNSFKNGNPAWTWGGSD
>NZ_CP046705.1|WP_114080946.1|208974_210297_-|MATE-family-efflux-transporter
MSIFAQHSVFIRHFLKLASVNVLSNLMVPLAGLIDVMFLGHLTEIRHLAGVAIATILFNYIYWTFGFLRMGTTGMVAQAIGRKDNQSAVLIGLQHGILALILGLAILIFQQPLQILGFAILSATPEVKSSGVDFYNALVWGAPATLINFVLIGWFLGQAQSSRALLLSAISNCANVLLDYLFIVQWGWSSRGAGLATATSQYLMLMVGILLYCQTISFKQIQALIGELFDLSALKSAFMLNGEIIIRTFALISTMAMFSNLSSMLGTEILAANTLLMQVVSLAAYFIDGLAFATESLAGIFQGSGNITSLKQLLQTSVVSSLVIGLMFATAFIFAPESLLRLLTNHTEIINNLRSYIPWLLPVLGFGSVAYALDGYFLGLTQGHTLRQAMLKATVIGFIPSAITAMYFHSSHLLWLSMSLFMATRTITLALCVPKSFSKR
>NZ_CP046705.1|WP_114080945.1|207828_208431_-|IS630-family-transposase
MHASEKYTERVQKLRAEYWTTIGSVLLEDLIFIDEAGVNISMTRRFARSLQGSRAYGDCPNARGKNVTMIGAMSTQGIIAAMTFTGGTNASAFQTYVTQVLVPNLWPGATVVMDNFSSHKVAGIREAIEGVGAKLVYLSPYSPDFSPIENCWSKVKEFLRSLAARTYQELDQAITDAFNAVTKKDIIGWFTHCCYYIAPN
>NZ_CP046705.1|WP_159402652.1|218771_218924_+|hypothetical-protein
MRAATTIVVSQLSDAAEPQLVENAEDVAQPMENFLGSDDILNSLKTKRIG
>NZ_CP046705.1|WP_114081254.1|218966_219419_-|DUF1392-family-protein
MINQITALESCWHISPEWGQTMPPVAVRMLEKVLLPISDLSGYCCGVLWEKQEWIYAIVCQNETLYLAEQEFYTTNVLKKSTVSTPAFRLGDIVEVDFGERPTRRIIQGIFSLKDNWLYGVEWRSPTLEEMSAQSRTIWLADVDLVNVSV
>NZ_CP046705.1|WP_114081253.1|219582_220071_-|TIGR00725-family-protein
MRRIIIGVMGRGENATANDLQDAYILGQFIAKQGWVLLTGGRNVGVMDAVSKGAKSADGLTIGILPGGNQDGMSSWVDIAIFTDMGNSRNNINVLTSDVIIACGMGAGTASEIALALKANKQVILLNNDQESKLFFKKLSPENVYIVESVEQAIATAKIILS
>NZ_CP046705.1|WP_084227073.1|220195_220471_-|UBP-type-zinc-finger-domain-containing-protein
MSCEHLDNLTTETLISKANYPVFRCEECILINSRWVHLRICQSCGKMLCCDSSVHQHARRHYEETGHSVISSAELGEQWLWCFLDEQAKNY
>NZ_CP046705.1|WP_114081252.1|220646_220838_-|hypothetical-protein
MTKEYMESLEAIVDQLTLAAVLEMLERISHKKAENLRNHWKDEASAKLWDKAARQIEQMNIDV
>NZ_CP046705.1|WP_159402653.1|220936_221077_+|hypothetical-protein
MPTKVTVKVLLKAYVCLSLLPAELKAMPAASYAGADNPTNPIIMKF
>NZ_CP046705.1|WP_114081255.1|221088_221574_+|bleomycin-resistance-protein
MLKRIDHIYLSVSNFSQSETFYDLVMRELGQHKGDKVIAEEPHAHYFGPQFQLTIQPARSAQKHDPYAPGLHHLCFQVETMTDVDLCFKKLRSVGINVSQPKRYPEYHPEYYAIFFDDPDGIRLEIVAKTSTRQALELRWDELKEFLNPLQTLPNTEFHNA
>NZ_CP046705.1|WP_167756041.1|221880_223113_-|hypothetical-protein
MDCGISFRAAEKVFELFNSESKITPSFTCIRKWLGRMGIYELTRKKEYRDDWIFIVDFTLELGKQKALVVLGVSQEHLSEQVVSKRRALSHEDVELLGLEIMGSTKGEMILHQLEKITELVGVPVQIVADHSSDLARGIKLYQENHPEIIYTHDVTHAMALLLKYKLDANDRYQSFLQKCHRCRQKLQQTELSFLSPPSQRSQCRYFNVERLTNWAIKLLNSPVETLIQLMPDIEHKLILSKIVEKLAWLADYETDLIHWNQMVTMTRRLETQLKQLGLNSQTLQYFQQNQSDLVNDSLQYFQQQIFDYVTNECSQIKDKQTFLATSDIIESLFGKYKQFSARCPIKEMGQMLLTICLSTMNLTTTVVKNALESISFFDVEEWLAEVFGQSMLSKRKTLYSTQINDTETA
>NZ_CP046705.1|WP_114080757.1|223196_223445_-|hypothetical-protein
MQEFKSPVSRLVRLFQKGRDSWREKALEKQKKVRALEIKVRDLTASREYWKQRALAAESEIKEQRIGGVSEKKKKMLARTST
>NZ_CP046705.1|WP_114080756.1|224034_224541_-|translation-initiation-factor-IF-3
MWESNVIAIPKQLINSQIKSPQVFLIDHENNNRGLTDINEALQLAESLELDLVLVSEGKEAPVAKILNYGKLQYQKKKRQAQSARPVVKEVRFGLNIGVADYKLRIEQAVGWLSKGDSVKFAVRLRGREHQYRDQAGELLDRVVTDLNSVGKVQSLDKRSLIALIIPA

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP046705_1	1.2|67894|30|NZ_CP046705|CRISPRCasFinder	67894-67923	30	NZ_CP046704.1	326849-326878	1	0.967
NZ_CP046705_2	2.1|152941|57|NZ_CP046705|CRISPRCasFinder	152941-152997	57	NZ_CP046704.1	223057-223113	2	0.965
NZ_CP046705_3	3.1|218646|38|NZ_CP046705|CRISPRCasFinder	218646-218683	38	NZ_CP046708.1	45893-45930	0	1.0
NZ_CP046705_3	3.1|218646|38|NZ_CP046705|CRISPRCasFinder	218646-218683	38	NZ_CP046708.1	49872-49909	1	0.974
NZ_CP046705_3	3.1|218646|38|NZ_CP046705|CRISPRCasFinder	218646-218683	38	NZ_CP046705.1	76103-76140	0	1.0
NZ_CP046705_3	3.1|218646|38|NZ_CP046705|CRISPRCasFinder	218646-218683	38	NZ_CP046705.1	214667-214704	1	0.974
NZ_CP046705_3	3.1|218646|38|NZ_CP046705|CRISPRCasFinder	218646-218683	38	NZ_CP046705.1	80082-80119	1	0.974
NZ_CP046705_3	3.1|218646|38|NZ_CP046705|CRISPRCasFinder	218646-218683	38	NZ_CP046715.1	171-208	1	0.974
NZ_CP046705_3	3.1|218646|38|NZ_CP046705|CRISPRCasFinder	218646-218683	38	NZ_CP046710.1	35911-35948	1	0.974
NZ_CP046705_3	3.1|218646|38|NZ_CP046705|CRISPRCasFinder	218646-218683	38	NZ_CP046709.1	37614-37651	1	0.974

1. spacer 1.2|67894|30|NZ_CP046705|CRISPRCasFinder matches to position: 326849-326878, mismatch: 1, identity: 0.967

tttgcagactaagtgaaattttcctcctaa	CRISPR spacer
tttgcggactaagtgaaattttcctcctaa	Protospacer
*****.************************

2. spacer 2.1|152941|57|NZ_CP046705|CRISPRCasFinder matches to position: 223057-223113, mismatch: 2, identity: 0.965

tagccaccatgtgggagtcaaattttgctcaagcctctaaactgctttggggtacat	CRISPR spacer
tagcccccatgtgggagtcaaattttgctcaagcccctaaactgctttggggtacat	Protospacer
***** *****************************.*********************

3. spacer 3.1|218646|38|NZ_CP046705|CRISPRCasFinder matches to position: 45893-45930, mismatch: 0, identity: 1.0

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccattgcaaataataatgagtctg	Protospacer
**************************************

4. spacer 3.1|218646|38|NZ_CP046705|CRISPRCasFinder matches to position: 49872-49909, mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

5. spacer 3.1|218646|38|NZ_CP046705|CRISPRCasFinder matches to position: 76103-76140, mismatch: 0, identity: 1.0

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccattgcaaataataatgagtctg	Protospacer
**************************************

6. spacer 3.1|218646|38|NZ_CP046705|CRISPRCasFinder matches to position: 214667-214704, mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

7. spacer 3.1|218646|38|NZ_CP046705|CRISPRCasFinder matches to position: 80082-80119, mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

8. spacer 3.1|218646|38|NZ_CP046705|CRISPRCasFinder matches to position: 171-208, mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

9. spacer 3.1|218646|38|NZ_CP046705|CRISPRCasFinder matches to position: 35911-35948, mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

10. spacer 3.1|218646|38|NZ_CP046705|CRISPRCasFinder matches to position: 37614-37651, mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP046705_1	1.1|67839|32|NZ_CP046705|CRISPRCasFinder	67839-67870	32	NZ_CP046705	Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence	67839-67870	0	1.0
NZ_CP046705_1	1.2|67894|30|NZ_CP046705|CRISPRCasFinder	67894-67923	30	NZ_CP046705	Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence	67894-67923	0	1.0
NZ_CP046705_2	2.1|152941|57|NZ_CP046705|CRISPRCasFinder	152941-152997	57	NZ_CP046705	Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence	152941-152997	0	1.0
NZ_CP046705_3	3.1|218646|38|NZ_CP046705|CRISPRCasFinder	218646-218683	38	NZ_CP046705	Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence	76103-76140	0	1.0
NZ_CP046705_3	3.1|218646|38|NZ_CP046705|CRISPRCasFinder	218646-218683	38	NZ_CP046705	Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence	218646-218683	0	1.0
NZ_CP046705_3	3.1|218646|38|NZ_CP046705|CRISPRCasFinder	218646-218683	38	NZ_CP046708	Nostoc sp. ATCC 53789 plasmid pNsp_e, complete sequence	45893-45930	0	1.0
NZ_CP046705_3	3.1|218646|38|NZ_CP046705|CRISPRCasFinder	218646-218683	38	NZ_CP046709	Nostoc sp. ATCC 53789 plasmid pNsp_f, complete sequence	41593-41630	0	1.0
NZ_CP046705_3	3.1|218646|38|NZ_CP046705|CRISPRCasFinder	218646-218683	38	NZ_CP046710	Nostoc sp. ATCC 53789 plasmid pNsp_g, complete sequence	39890-39927	0	1.0
NZ_CP046705_3	3.1|218646|38|NZ_CP046705|CRISPRCasFinder	218646-218683	38	NZ_CP046715	Nostoc sp. ATCC 53789 plasmid pNsp_l, complete sequence	4150-4187	0	1.0
NZ_CP046705_1	1.2|67894|30|NZ_CP046705|CRISPRCasFinder	67894-67923	30	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	326849-326878	1	0.967
NZ_CP046705_3	3.1|218646|38|NZ_CP046705|CRISPRCasFinder	218646-218683	38	NZ_CP046705	Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence	214667-214704	1	0.974
NZ_CP046705_3	3.1|218646|38|NZ_CP046705|CRISPRCasFinder	218646-218683	38	NZ_CP046705	Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence	80082-80119	1	0.974
NZ_CP046705_3	3.1|218646|38|NZ_CP046705|CRISPRCasFinder	218646-218683	38	NZ_CP046708	Nostoc sp. ATCC 53789 plasmid pNsp_e, complete sequence	49872-49909	1	0.974
NZ_CP046705_3	3.1|218646|38|NZ_CP046705|CRISPRCasFinder	218646-218683	38	NZ_CP046709	Nostoc sp. ATCC 53789 plasmid pNsp_f, complete sequence	37614-37651	1	0.974
NZ_CP046705_3	3.1|218646|38|NZ_CP046705|CRISPRCasFinder	218646-218683	38	NZ_CP046710	Nostoc sp. ATCC 53789 plasmid pNsp_g, complete sequence	35911-35948	1	0.974
NZ_CP046705_3	3.1|218646|38|NZ_CP046705|CRISPRCasFinder	218646-218683	38	NZ_CP046715	Nostoc sp. ATCC 53789 plasmid pNsp_l, complete sequence	171-208	1	0.974
NZ_CP046705_1	1.2|67894|30|NZ_CP046705|CRISPRCasFinder	67894-67923	30	AP018319	Nostoc sp. HK-01 plasmid plasmid1 DNA, complete genome	251009-251038	2	0.933
NZ_CP046705_2	2.1|152941|57|NZ_CP046705|CRISPRCasFinder	152941-152997	57	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	223057-223113	2	0.965
NZ_CP046705_3	3.1|218646|38|NZ_CP046705|CRISPRCasFinder	218646-218683	38	AP018278	Calothrix sp. NIES-4101 plasmid plasmid5 DNA, complete genome	21799-21836	3	0.921
NZ_CP046705_1	1.2|67894|30|NZ_CP046705|CRISPRCasFinder	67894-67923	30	NC_010631	Nostoc punctiforme PCC 73102 plasmid pNPUN01, complete sequence	163412-163441	5	0.833
NZ_CP046705_1	1.2|67894|30|NZ_CP046705|CRISPRCasFinder	67894-67923	30	NC_010631	Nostoc punctiforme PCC 73102 plasmid pNPUN01, complete sequence	179688-179717	5	0.833
NZ_CP046705_1	1.2|67894|30|NZ_CP046705|CRISPRCasFinder	67894-67923	30	NZ_CP020115	Nodularia spumigena UHCC 0039 plasmid pUHCC0039a, complete sequence	69515-69544	5	0.833
NZ_CP046705_1	1.2|67894|30|NZ_CP046705|CRISPRCasFinder	67894-67923	30	NZ_CP046705	Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence	67817-67846	7	0.767
NZ_CP046705_1	1.2|67894|30|NZ_CP046705|CRISPRCasFinder	67894-67923	30	NZ_CP046705	Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence	67872-67901	7	0.767
NZ_CP046705_1	1.2|67894|30|NZ_CP046705|CRISPRCasFinder	67894-67923	30	NZ_CP046704	Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence	326926-326955	7	0.767
NZ_CP046705_1	1.2|67894|30|NZ_CP046705|CRISPRCasFinder	67894-67923	30	AP018319	Nostoc sp. HK-01 plasmid plasmid1 DNA, complete genome	250978-251007	7	0.767
NZ_CP046705_1	1.2|67894|30|NZ_CP046705|CRISPRCasFinder	67894-67923	30	AP018319	Nostoc sp. HK-01 plasmid plasmid1 DNA, complete genome	251031-251060	7	0.767
NZ_CP046705_1	1.1|67839|32|NZ_CP046705|CRISPRCasFinder	67839-67870	32	NZ_CP026682	Nostoc sp. 'Peltigera membranacea cyanobiont' N6 plasmid pNPM1, complete sequence	147563-147594	8	0.75
NZ_CP046705_1	1.2|67894|30|NZ_CP046705|CRISPRCasFinder	67894-67923	30	AP018319	Nostoc sp. HK-01 plasmid plasmid1 DNA, complete genome	251086-251115	8	0.733
NZ_CP046705_1	1.2|67894|30|NZ_CP046705|CRISPRCasFinder	67894-67923	30	NC_010631	Nostoc punctiforme PCC 73102 plasmid pNPUN01, complete sequence	163225-163254	8	0.733
NZ_CP046705_1	1.2|67894|30|NZ_CP046705|CRISPRCasFinder	67894-67923	30	NC_010631	Nostoc punctiforme PCC 73102 plasmid pNPUN01, complete sequence	163465-163494	8	0.733
NZ_CP046705_1	1.2|67894|30|NZ_CP046705|CRISPRCasFinder	67894-67923	30	NC_010631	Nostoc punctiforme PCC 73102 plasmid pNPUN01, complete sequence	179501-179530	8	0.733
NZ_CP046705_1	1.2|67894|30|NZ_CP046705|CRISPRCasFinder	67894-67923	30	NC_010631	Nostoc punctiforme PCC 73102 plasmid pNPUN01, complete sequence	179741-179770	8	0.733
NZ_CP046705_1	1.2|67894|30|NZ_CP046705|CRISPRCasFinder	67894-67923	30	NZ_CP026682	Nostoc sp. 'Peltigera membranacea cyanobiont' N6 plasmid pNPM1, complete sequence	147541-147570	8	0.733
NZ_CP046705_1	1.2|67894|30|NZ_CP046705|CRISPRCasFinder	67894-67923	30	NC_019764	Oscillatoria nigro-viridis PCC 7112 plasmid pOSC7112.04, complete sequence	9014-9043	8	0.733
NZ_CP046705_1	1.2|67894|30|NZ_CP046705|CRISPRCasFinder	67894-67923	30	NC_010631	Nostoc punctiforme PCC 73102 plasmid pNPUN01, complete sequence	163520-163549	9	0.7
NZ_CP046705_1	1.2|67894|30|NZ_CP046705|CRISPRCasFinder	67894-67923	30	NC_010631	Nostoc punctiforme PCC 73102 plasmid pNPUN01, complete sequence	179796-179825	9	0.7

1. spacer 1.1|67839|32|NZ_CP046705|CRISPRCasFinder matches to NZ_CP046705 (Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence) position: , mismatch: 0, identity: 1.0

tttaacgcagtaataagggtttgggcaacctt	CRISPR spacer
tttaacgcagtaataagggtttgggcaacctt	Protospacer
********************************

2. spacer 1.2|67894|30|NZ_CP046705|CRISPRCasFinder matches to NZ_CP046705 (Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence) position: , mismatch: 0, identity: 1.0

tttgcagactaagtgaaattttcctcctaa	CRISPR spacer
tttgcagactaagtgaaattttcctcctaa	Protospacer
******************************

3. spacer 2.1|152941|57|NZ_CP046705|CRISPRCasFinder matches to NZ_CP046705 (Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence) position: , mismatch: 0, identity: 1.0

tagccaccatgtgggagtcaaattttgctcaagcctctaaactgctttggggtacat	CRISPR spacer
tagccaccatgtgggagtcaaattttgctcaagcctctaaactgctttggggtacat	Protospacer
*********************************************************

4. spacer 3.1|218646|38|NZ_CP046705|CRISPRCasFinder matches to NZ_CP046705 (Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence) position: , mismatch: 0, identity: 1.0

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccattgcaaataataatgagtctg	Protospacer
**************************************

5. spacer 3.1|218646|38|NZ_CP046705|CRISPRCasFinder matches to NZ_CP046705 (Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence) position: , mismatch: 0, identity: 1.0

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccattgcaaataataatgagtctg	Protospacer
**************************************

6. spacer 3.1|218646|38|NZ_CP046705|CRISPRCasFinder matches to NZ_CP046708 (Nostoc sp. ATCC 53789 plasmid pNsp_e, complete sequence) position: , mismatch: 0, identity: 1.0

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccattgcaaataataatgagtctg	Protospacer
**************************************

7. spacer 3.1|218646|38|NZ_CP046705|CRISPRCasFinder matches to NZ_CP046709 (Nostoc sp. ATCC 53789 plasmid pNsp_f, complete sequence) position: , mismatch: 0, identity: 1.0

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccattgcaaataataatgagtctg	Protospacer
**************************************

8. spacer 3.1|218646|38|NZ_CP046705|CRISPRCasFinder matches to NZ_CP046710 (Nostoc sp. ATCC 53789 plasmid pNsp_g, complete sequence) position: , mismatch: 0, identity: 1.0

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccattgcaaataataatgagtctg	Protospacer
**************************************

9. spacer 3.1|218646|38|NZ_CP046705|CRISPRCasFinder matches to NZ_CP046715 (Nostoc sp. ATCC 53789 plasmid pNsp_l, complete sequence) position: , mismatch: 0, identity: 1.0

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccattgcaaataataatgagtctg	Protospacer
**************************************

10. spacer 1.2|67894|30|NZ_CP046705|CRISPRCasFinder matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 1, identity: 0.967

tttgcagactaagtgaaattttcctcctaa	CRISPR spacer
tttgcggactaagtgaaattttcctcctaa	Protospacer
*****.************************

11. spacer 3.1|218646|38|NZ_CP046705|CRISPRCasFinder matches to NZ_CP046705 (Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence) position: , mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

12. spacer 3.1|218646|38|NZ_CP046705|CRISPRCasFinder matches to NZ_CP046705 (Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence) position: , mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

13. spacer 3.1|218646|38|NZ_CP046705|CRISPRCasFinder matches to NZ_CP046708 (Nostoc sp. ATCC 53789 plasmid pNsp_e, complete sequence) position: , mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

14. spacer 3.1|218646|38|NZ_CP046705|CRISPRCasFinder matches to NZ_CP046709 (Nostoc sp. ATCC 53789 plasmid pNsp_f, complete sequence) position: , mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

15. spacer 3.1|218646|38|NZ_CP046705|CRISPRCasFinder matches to NZ_CP046710 (Nostoc sp. ATCC 53789 plasmid pNsp_g, complete sequence) position: , mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

16. spacer 3.1|218646|38|NZ_CP046705|CRISPRCasFinder matches to NZ_CP046715 (Nostoc sp. ATCC 53789 plasmid pNsp_l, complete sequence) position: , mismatch: 1, identity: 0.974

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

17. spacer 1.2|67894|30|NZ_CP046705|CRISPRCasFinder matches to AP018319 (Nostoc sp. HK-01 plasmid plasmid1 DNA, complete genome) position: , mismatch: 2, identity: 0.933

tttgcagactaagtgaaattttcctcctaa	CRISPR spacer
tttgcagacttagtgaaattttccccctaa	Protospacer
********** *************.*****

18. spacer 2.1|152941|57|NZ_CP046705|CRISPRCasFinder matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 2, identity: 0.965

tagccaccatgtgggagtcaaattttgctcaagcctctaaactgctttggggtacat	CRISPR spacer
tagcccccatgtgggagtcaaattttgctcaagcccctaaactgctttggggtacat	Protospacer
***** *****************************.*********************

19. spacer 3.1|218646|38|NZ_CP046705|CRISPRCasFinder matches to AP018278 (Calothrix sp. NIES-4101 plasmid plasmid5 DNA, complete genome) position: , mismatch: 3, identity: 0.921

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
tgacgattgcaagcccgttgcaaataataatgagtctg	Protospacer
 **.************.*********************

20. spacer 1.2|67894|30|NZ_CP046705|CRISPRCasFinder matches to NC_010631 (Nostoc punctiforme PCC 73102 plasmid pNPUN01, complete sequence) position: , mismatch: 5, identity: 0.833

tttgcagactaagtgaaattttcctcctaa	CRISPR spacer
ttcgcagactaaatgaaattttccacaaaa	Protospacer
**.*********.*********** *  **

21. spacer 1.2|67894|30|NZ_CP046705|CRISPRCasFinder matches to NC_010631 (Nostoc punctiforme PCC 73102 plasmid pNPUN01, complete sequence) position: , mismatch: 5, identity: 0.833

tttgcagactaagtgaaattttcctcctaa	CRISPR spacer
ttcgcagactaaatgaaattttccacaaaa	Protospacer
**.*********.*********** *  **

22. spacer 1.2|67894|30|NZ_CP046705|CRISPRCasFinder matches to NZ_CP020115 (Nodularia spumigena UHCC 0039 plasmid pUHCC0039a, complete sequence) position: , mismatch: 5, identity: 0.833

tttgcagactaagtgaaattttcctcctaa	CRISPR spacer
ttcgcagactaaatgaaattttcctttaaa	Protospacer
**.*********.************.. **

23. spacer 1.2|67894|30|NZ_CP046705|CRISPRCasFinder matches to NZ_CP046705 (Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence) position: , mismatch: 7, identity: 0.767

tttgcagactaagtgaaattttcctcctaa	CRISPR spacer
tttgcagactaagtgaaatttttttaacgc	Protospacer
**********************..*  .. 

24. spacer 1.2|67894|30|NZ_CP046705|CRISPRCasFinder matches to NZ_CP046705 (Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence) position: , mismatch: 7, identity: 0.767

tttgcagactaagtgaaattttcctcctaa	CRISPR spacer
gttgcagactaaatgaaatttttttgcaga	Protospacer
 ***********.*********..* * .*

25. spacer 1.2|67894|30|NZ_CP046705|CRISPRCasFinder matches to NZ_CP046704 (Nostoc sp. ATCC 53789 plasmid pNsp_a, complete sequence) position: , mismatch: 7, identity: 0.767

tttgcagactaagtgaaattttcctcctaa	CRISPR spacer
tttgcagactaagtgaaatttttttaacgc	Protospacer
**********************..*  .. 

26. spacer 1.2|67894|30|NZ_CP046705|CRISPRCasFinder matches to AP018319 (Nostoc sp. HK-01 plasmid plasmid1 DNA, complete genome) position: , mismatch: 7, identity: 0.767

tttgcagactaagtgaaattttcctcctaa	CRISPR spacer
ttcgcagactaaatgaaattttctcaatta	Protospacer
**.*********.**********..  * *

27. spacer 1.2|67894|30|NZ_CP046705|CRISPRCasFinder matches to AP018319 (Nostoc sp. HK-01 plasmid plasmid1 DNA, complete genome) position: , mismatch: 7, identity: 0.767

tttgcagactaagtgaaattttcctcctaa	CRISPR spacer
gttgcagactaaatgaaatttttttgcaga	Protospacer
 ***********.*********..* * .*

28. spacer 1.1|67839|32|NZ_CP046705|CRISPRCasFinder matches to NZ_CP026682 (Nostoc sp. 'Peltigera membranacea cyanobiont' N6 plasmid pNPM1, complete sequence) position: , mismatch: 8, identity: 0.75

tttaacgcagtaataagggtttgggcaacctt	CRISPR spacer
tttaacgcaagaataagggtttggtgtgggtt	Protospacer
*********. *************   .  **

29. spacer 1.2|67894|30|NZ_CP046705|CRISPRCasFinder matches to AP018319 (Nostoc sp. HK-01 plasmid plasmid1 DNA, complete genome) position: , mismatch: 8, identity: 0.733

tttgcagactaagtgaaattttcctcctaa	CRISPR spacer
tttgcagactaagtgaaattttttcaacgc	Protospacer
**********************...  .. 

30. spacer 1.2|67894|30|NZ_CP046705|CRISPRCasFinder matches to NC_010631 (Nostoc punctiforme PCC 73102 plasmid pNPUN01, complete sequence) position: , mismatch: 8, identity: 0.733

tttgcagactaagtgaaattttc-----ctcctaa	CRISPR spacer
tttgcagactaaatgaaatttgtgcggact-----	Protospacer
************.******** .     **     

31. spacer 1.2|67894|30|NZ_CP046705|CRISPRCasFinder matches to NC_010631 (Nostoc punctiforme PCC 73102 plasmid pNPUN01, complete sequence) position: , mismatch: 8, identity: 0.733

tttgcagactaagtgaaattttcctcctaa	CRISPR spacer
gttgcagactaaatgaaattttttcgcgga	Protospacer
 ***********.*********... * .*

32. spacer 1.2|67894|30|NZ_CP046705|CRISPRCasFinder matches to NC_010631 (Nostoc punctiforme PCC 73102 plasmid pNPUN01, complete sequence) position: , mismatch: 8, identity: 0.733

tttgcagactaagtgaaattttc-----ctcctaa	CRISPR spacer
tttgcagactaaatgaaatttgtgcggact-----	Protospacer
************.******** .     **     

33. spacer 1.2|67894|30|NZ_CP046705|CRISPRCasFinder matches to NC_010631 (Nostoc punctiforme PCC 73102 plasmid pNPUN01, complete sequence) position: , mismatch: 8, identity: 0.733

tttgcagactaagtgaaattttcctcctaa	CRISPR spacer
gttgcagactaaatgaaattttttcgcgga	Protospacer
 ***********.*********... * .*

34. spacer 1.2|67894|30|NZ_CP046705|CRISPRCasFinder matches to NZ_CP026682 (Nostoc sp. 'Peltigera membranacea cyanobiont' N6 plasmid pNPM1, complete sequence) position: , mismatch: 8, identity: 0.733

tttgcagactaagtgaaattttcctcctaa	CRISPR spacer
tttgcagactaagtgaaaattttttaacgc	Protospacer
****************** ***..*  .. 

35. spacer 1.2|67894|30|NZ_CP046705|CRISPRCasFinder matches to NC_019764 (Oscillatoria nigro-viridis PCC 7112 plasmid pOSC7112.04, complete sequence) position: , mismatch: 8, identity: 0.733

tttgcagactaagtgaaattttcctcctaa	CRISPR spacer
tttgcagaataagtgaaatttttttgacgt	Protospacer
******** *************..*  .. 

36. spacer 1.2|67894|30|NZ_CP046705|CRISPRCasFinder matches to NC_010631 (Nostoc punctiforme PCC 73102 plasmid pNPUN01, complete sequence) position: , mismatch: 9, identity: 0.7

tttgcagactaagtgaaattttcctcctaa	CRISPR spacer
tttgcagactaaatgaaattttttcaacgt	Protospacer
************.*********...  .. 

37. spacer 1.2|67894|30|NZ_CP046705|CRISPRCasFinder matches to NC_010631 (Nostoc punctiforme PCC 73102 plasmid pNPUN01, complete sequence) position: , mismatch: 9, identity: 0.7

tttgcagactaagtgaaattttcctcctaa	CRISPR spacer
tttgcagactaaatgaaattttttcaacgt	Protospacer
************.*********...  .. 

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	70364 : 87092	14	Bacillus_phage(100.0%)	integrase,transposase	attL 68717:68731|attR 89541:89555
DBSCAN-SWA_2	112551 : 178095	49	Bacillus_phage(33.33%)	integrase,transposase	attL 109731:109748|attR 134579:134596
DBSCAN-SWA_3	186481 : 233000	46	Brochothrix_phage(20.0%)	integrase,transposase	attL 214613:214637|attR 218618:218642

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP046705|70364:87092|DBSCAN-SWA
ATTAGAACTCTCCATAATATTCAAGGGTTTCCGTGATATATGCAGTCAAATTGCTGATAGTTTCACAATTTTTACCTTCATTGGTCGAGTCATCTCCTAGACAATCATTATTTTCCTCTGCCGCAAATTCTGCCAAATTTAACTTTGGTTCCGTGATCAAATTATTTTGAATAATTTTGTGAACTTTGTCATGTTCAGTATCGCGCAAGCGTTGTTTGAGGATAGCACCTTCTTGAGCAAATTTTGAGTTTAAAAATTCTACTAATTCCCGATCATTTATTGTTAACTTACGTCCGTAATTGCGTTGGCGCTGATTAAGTTCTGCACTCGCCAGCCGAATTTCTTTTTCGGAACGTCCTTGGAAGTATTGATAGTAAGAAGAAATGCATTTTACCCACTGTCCTTGTGCTAGTGCATAAGCAATTCCTGCATTCCAAGGGTCGTAACGAACCCACAGCATTGATTTTTCGATTTCTGGATCACGGAATACATCTGCCCAGTAATAAATATTGTGTATTTTGACACCCTTTCCTGGTTGAACTTTACGCTTTCGTTGATCTGGTGCTGGTAGAGTCAGAATCTGGAATAATTCGTCATATGCTACTCTTCGGTGTAAGCGACTTCCACCTGTTGCTAATCCGGTGACAAAAGCATCGCACGGACTAGTACCTAATGCCGGATGCAATCGTTGGTCATAAACCGAATATGCCCATTCACAAAAAGCAGAGTACAGTTCTTCTAGTGTCCAAATTGCTAATCTTTCTGGACTGACAGATTTGGTGACTTTACGGTGAAGGCGTTTGATTTGGGTGTTACCTTGCAACTCATGAATAAACTGCGTGTTGGCAGTCCCAAATAGTCTTTCAACAATTGAACCAAACCGAGCATGTGCTGGCGGTCGATACTTCAGCGTGCAAGTATAAGATGCCAATAATTGTTCAAAATAGTGACTGTGAAACTCTTTTCCGTTATCGACAACAATATTTTGCGGAAACCGCCCAAATCTAGCAACGCATATGCGAATTACCATCATACAATCACGGTAGCTTGGCTCATCGAAGGTCAGATAAACTGATAAAATTCTTCGACTATATGCATCAACCATGAAGGTTGCCCAAGGACGACCTAAATTCTGATGAATTGAGTTATTTGTAGCAATATGACAATTAGTTAGAGATTCGAGTGAACTGACTAATTCAATGTCAATTTGAGTATGGTCAATGTGAACAATCTCAAAAGGGCGACTGCCATGCCGTGGAGTAGTTTGCTTTAATTCCCAATAAAATGGTTCTTCGGAAATAGCCGCTCGATTACCAAGACGTTTTCTGGTTTGATGATGTCCGCTTCGCTGTTTGATAGCATGGCAAAATGTGATTCTCGATGGTGGTTTGAATGGGGGGTCATGGGTTTGGCAAGCTAAAACAAATGATTCATAAACCCGTATTTTTCTGCGTTGTTTGGGTGTTTCATAATGCTCTTTGATAAAATCGAGCATAAATTCTTGGGTTTGAGAATCAATTTTTGGAGTCCGATTGCCTTTATTGTTATGTTTAGGCAGTAATCCCAGGTATCCCTGTCCATAAATGAGTAAAGCTTTTTGGTACTGAGTGCGCCAACGACGGATTGTGCTGCTTGGATATGCTTTCAGAGCATCTTCTAAGTATGGTTGTATTAAATTGTAGCGACGGTTGGCTTCTATAATATCTTCACAAGTTGCGTGTTTAATAATTTCTGCTGCTGCTAAGTAGCTAGGCACAATTAAATATAAGACGCTCAAGGGCATATTCCCCCTTTACGCTTCTAGCTTCCATGCCATCAATAATTGCCATAGCCAAATCGTAGTTATTGTCAAACATTTGTCCAGCAATTTCATGAGTTTTTAGTTGATGCCACTCTTCCTCTATCCGATTCATTTCGGAACAATAAGGTGGTAAAAAGAAAACGAATAATCCTTTTTCCTGCCACTCAAGCCATTTTTGTTTTGCTTTCTTACTGGTATGTAAGGAACCATTATCGTGAACAATAACACTGATGCGACCAGTTTCAACTAAAGTGTTTTGTGCCTTAGCTGCAACCCAATCCATAACCTCGATGTAGCGTTTTGTTTTGAACCCACCTTGAACCAAGGCATATTCAAAACTGACTTGGGGTTGCCATAAACCCAAAATACTAATGCGACCACCACGGCTACCAACTTGTGCCATTTGTTTTTGGCTACCGATACGACTGTAACTATAGCTAACGGGACTCCAACGACAACACCCAGACTCATCAAGATACTTAAGCTCGACATAACCCTCTACTGCCGCTTGCTTTAAGGTATCTAGGTCTGCTTGCTTAATTCGTCGTTTTTCTGGGTCTTGTTTTCTCTTATGAGTATGGCGGGTGCGTTTCCATTTCCACTTTTTTTTGAGCAAACGTCGCAAACGAGACGGACTCAATTGCACATTTCTATCTTGAGCCAATTTTTCTGATAACTGCAAACTGTTATAAGTACGGGGCTCTACCTCTAAGCAATCCTCTAAATATGCTAAGTCTGCCTCAAGCCATTTGCACTTTGCTCCTCGCCCGGAAGTTTCCCACAGTCCTCCCAAACCCTTATTTTCCCAACGCCTCAGTGTTGCTCGTACCGTATGTTCGTGACACTCAAAAATTTTAGCTATCGCTGGTACATTCCATCCTTGGGCATTTAATCGAATTATGTGGGCACGCTCTCGTGTCCGTTGAGGAACTGTTGTCGCTGACCGTAACTCCAAAAGCGTCAAATCTTCTAAATCTGTTAATCTAACTCGCAATGGAGCAGACATCTCGTAGAACCTATTTTTTAGACCTTCTCTATCTTATATTTAATTGTAACCACCTACTTATTTTAATATTTGAGGTTTGTGTTGTCTTATCTCCCACAATTTTCCCTGTATCAATCAATGCTGTAAATGCTAAATTTGGTAGTTCTATAAGTTTGCCATCTGCACGTAATAATCCAGTAGTGGTCGTCCCAGTATTTACTATCTCCCATGACTCTCCATCCCAATAAATATTAGTACCTACTGCTATTTGGAGTAATATTTGATTACTCGTTTGGGTTGTAGATTCTATTGAGTTAAGATGCTCATAAGATAAAGCAACATTTTGGTTAATAAATACGAATACTGTTTCCGGTTGCGAAAGTTTAACTTTATTAAGTTCTACGTAAAGTTTATCTGTAGCAATTAACCAATAAAGTACATCAGGGTTTATTTCTTCATTTTTTAACAGTTCTGTCAGGGTCATTCCTAGATGATTGTTTACTGTGTTTACAATCAAACTTTGCTCGGTTTCGTCTATAATTTCTGATGAGTATCCGAAATAATCTAACAGCCAAATTAGATTTTGTTGGAAGTTCCAATTAATTAGAGCATCTGACCATACATGAAAGTCCAAACCATGACCATGAGCGTATTCTTCACCTGGGGGACAATGCCATTTGCCATCTGAGTTTTTGCAATAGCGATTTGGATTCAATTCGTTCAGCTTGTTAAGTTCAAGTTCTGTTTTGCATTCCTCCCAAAAAGCTGAATCTGTCCGAATTATAAAGAAATCGGGTGTATACTGGTGTCTATTTTTTCGCCCGCTTTTGCTTTGATAGACTAATTCTATTGCTGGCGGTTGGTCGTAATATTCGAGTACGCATGGGTCATGTTCTAGTTCATAAATACGTGCTAATTCGTTATGATGGCTCTCGAATTGAATAGTACATCCCATTTTTCGACTGGGGTAACTGCCACAAACGTTTTTCCTTGCCCCTGTTACTCGACGAGATGGATTGCTGCTGCGAATCTCCTCAATGATTGCCTGCCCTGCTTGACTGAGGTCTTGTTGACGGCACCAGTTGTTAAACTCAAGGTTGTCAAGCATAATTCTTGGTTAGGAGAGAGTGTTGCGATCATTAATCTCTCCTACTCTTTATCTCAGCACAAGGCTGTATATTTATGAACAAAGTGTTGAAAATGTTTGCTCAACTTATACTTTCTCAATCATATTTTTGCTCAACTTATGCTTTCAAAACTCCTATATTTATTTTTTCCTTCTAACATGGTTAATACGGTTTCAAGCAATCTGTTGCTCAACTTATGCTTTCAAAGTTGCTCATTTTATCCTTACAGTGACAATTATTTTGTGACTTTAGCCATAAGTTGTCAAAATCAGACAAATTATGCCTTGTAATCAAGTCGGACAACTTATGCTTGGATTTTTGGGTTGAAGGAAAATAAAGTAGAGCTGTTGTTATCTTGTTGCTTGCCTTACTGAATTTCGAGCAAGTTTAAACCCTCGACAGGAGATAAACTAAGCTTGTAACACCATCTCAAAAACTTGTATAAAGTAGGCAATGTTCGTTTAGGGGTAACTTTTGTTTCTCTGATGAGGGGATTTGTGTGGAGTGAGGGAGTAGCAGCAAGCAGATTTCCAAGAGCTTGAGCAATCCACAAATCCCGATCAAATTTGCGCCCTTTGCTTCGGCTATGACTCGGTAGGTCAAGATTGCGCCCAAGCCAAGCATCACACTCGTGACAGTAGCCGTTTAGTTTCTGAGGTTGGAAAAAAGGTTGGGTATGACCGTAGCACAAACAGTATATTTGTAAATAGCGTTGATGGTATGGGCAGACAGTTACAGGCTCTAACGCCCATAACAGAGGTTGATATACAGGGGTATTAGCATCACGCCAATCTTGGTAACAACCTGCACACCAACGCTGCTGTGTATGGAAGATGTGGTTAAATGAAAGTCGCCAAGTTTTCCAAGGCAACAAAGTTAAATAGCTGATATCTTTGCGACCAGTTAAGATTTCTAGTACATTAACAACCTTAGAAACATGCTGTGTTTGGGAAAGCCAAAATTGGGCAGTTGGTTGCTGCAAAATGGCTAGTTCTTTTCGCAATCTAACTACAACTAGCTCGATAGCATCTTTTTTGGATAATCCTGGAGGCTGCTCGTTAAGAAAAAATAAAGGAGCAATGTAATAGCGAATCAAGCCCCCAACTGTAATTCCATGTGCATCAGCCAAGCGAATTAAGTAGCTACTCAAGCTCTCGACAATTGCTGTGCCGACACCAACTGGTGGTAGAGAGAAAAGACGGCTACGCTCAGGTAGTATGGGTTGCTCTAATTCCCATGATTGATACAATTTCAAGTTCTCAACAGGCATTGTGTCCACCACCGACAGGACGACGCTGTGGCAGAGGCTGACCGACCGCAGCGTGACGACGAGTTTGTTTAGCAGATGTCTGCAATGTTTTTGGAGTCACATCAGTTGCGACTTCTAATCCCAAAGCAGCCCGCAGAGCGTTGGTATCCCTACGGCTATTAAGTTGTTCCTCCCCATGAAGAGCTTCGTTAAGCAGAATTATGCACTGCTCAGTTTTGAGAGCATGTGACTCAAGATCGGAAAAAGTTAAAGTTTTGTCACCTTTGAGCAAAGCACTAAATAAAGCACGAGATAACCAATCTTTGAGAATGCCGATACAACCAACACAGCGCTCATAGCAGAAGTCCCAATGTTTGAGCAAATCAGGTTCAATTTGCAATGGTAAATGTCGTTGGAATGTTTGTACTATACCTTGAAAAGCTCTTAAATCTTCTGAATTGTCTGCTTTATAGCTGTTGCGGCTCGCAAACATAAACGCTCCGGCTTGCAAACAAGAAAATTCTTGGCTCACATTAGTTGCAAATCAGATTGGACTTCGGCTCACATTAATTGCAAACAGACTCATTATTATTTGCAATGGGCTTGCAATCATCCGACTTGGCTCACATTAATTGCAAATAAGCCGAATGCCTGCTCAGCAACTGTTGGATAGAGCAATATAAAATCCTTTGGGCGTTGCTATCTCTCCTTTATCCCTTGAGTAATGCAAGCTTGTCTTTCACTTGCTGTCGGCTACTTTGAGTGTACCGAACCGTGGTTTGAATAGCTGGAGTTCCCTTTTTGGTGATATGACCAAGATAATAAGCAACCTCCTCCAAAGTCCATCCTGCTTCACGCGCTCGGTGAGCGAAATCATGACGCAGATCATGAAAAGTTACATCATGGATGAGTTCCCACTCAGAAACAGTTGCTTGTGCTTTAATGTTTTTCCACCAGCGATGAATGCCGGCTTCGGTCAGCCTCTCATTGCGCTGAGAGGTAAAAGTGTAATCACTCTCAGTATCTCGCCCGCCGTGATGAATATATTCATACATTGGTTTTCGGACAGCGTTAATTAGATCAATATCTCGCGCCTTACCACCCTTGTAACCAACGTGCAACCAGCCAACTTTGGGGCCAATATGGGTATGCTCTATCCGTAGCCAGGAAACATCACTCACGCGACAACCAGCCCAGTACCCCAATGCAAACACAGCCATGCTACGTGGATGACCATCTTTTTCGATCAGGTTGCGTAAAATATAACGTTGGTCAGGAGTCAATTGTCTGGGGGCTAAAAGTGGCTGGGCTGGAATGTTTAATCCTCTGGTGGGGTTGCGACGTAAAATTCCCTTCTCCTCAATGAGCCAACGGGCAAAACCACTGACAGCAGATTTAACCCGTGCTTGGTGAGCAATGCTGTAACCTGACGTATCTAGATAGGCGAGATAAATTTCCATCGCCGTTTTGGTCAACTGTTCGGGTTGAAAATCTCCTCCACTCCCAGGATGTTCTACAATCCAAAGAAGAAGCTGCCTAATGATACGCATATAGGCATCAATAGTGCTATGCGTTTTACCTTTTAGGAACGCCTCATACTCTATGAGTAGTGCTTCGGCTTCAGATAAGTAAAGTGTATCCACAGCACCAAACTTCCTTCAAAAATTTCTGTGGTGAGTTTTCAAGCCTCATTTGAAGCTAATCTATCTCAAATTGTTATACTTTTTCACCTAACTGGCAACAGAATGTAATTTCTGTGGTCAGTTTTCTGCTACAAACTTAAAGATAAGGACAGTACATGAGGCGAACATACAGGCGAGCATGATCCGCAAGAAAATTCCAGCAGAAGCTTTAACCAACTTGCGTCATCGACTTGATATGTTACCAAGCCGTTGCCAAGAACGTCGGCAACTCATGGAAGAAACAGCTTCATTGTATGGAGTGTCTATTGATACTCTATATCGTGCTTTGCGTAACTCATCACGCCCCAAATCGATCAACCGTTCAGATAGCGGGACACCTCGAAAGCTATCACAGGCGGAAATGGAACTTTACTGTGAAGTCATTGCAGCAACGAAAATCCGCACTTGCAACAAGAAAGGGCGGCACGTCTCCACTGCACGGGCGATTGAACTTTTAGAAGATTTCGGGATGAACACCCCACAAGGTTTTATCAAACCACCCAAGGGGTTGTTAACTAAAGCCACTGTCAACCGTTATTTGAAAACATGGGGCTACGACCATCTCACAATGACTCGTCAACCGCCTGCGGTACGTTTTCAAGCAACTCACAGTAATGAATGTTGGCATTTCGACCTTAGCCCGTCCGATTTAAAACACGTAAAGCAGCCCTTATGGGTGGAAACGGGTAAAGGGAATCCGCTATTGATGCTTTATAGTGTCGTTGATGACCGCAGTGGTGTGTGTTACCAGGAATACCATTGTGTTTATGGAGAGGATGTAACAGCAGCGTTGCGCTTCCTATTTAATGCAATGACGGCTTCCACCTCGGATGGATGCCCCTTCCAGGGAATTCCTGAGATGATCTATACGGACAACGGGCCAATTGCCAAAAGCCATGTATTTCAAAATGTGATGGACTGCCTGGGAATCAAGCTTGCTAGCCATCTGCCTGCGGGTAAAGATGGGAGAAGGGTAACGGCTCGCTCCAAAGGAAAAGTGGAAAGACCGTTCCGGACAGTCAAAGAAGCCCATGAGACTCTGTATCATTTTCACGAACCAGAAAACGAAGTTGAGGCTAACCTATGGCTACGGCAGTATCTGCTAAATTATAACGACCAAAAACACCGTACAGAAGCGCACTCACGCTTAGAGGATTGGTTGCGAAATCTGCCAAAAAGCGGAATCAGGCAGATGTGTAGTTGGGAACGATTTTGTACTTTTGCCCGCGAACCGCAACGAAGGAAAGTGGATGCAACAGCCAGAGTATCAGTTGAGGGCGTGGCTTATGAAGTAAACCCAGACTTAGCAGGCGAAACTGTGGTGCTGTGGTGGGGTCTTTTTGATAACGAATTATATGTAGAGAAAGGCGACCAACGCTATGGCCCATTTTACCCAGTTGATGGGCCTATCCCCTTGCATCGCTATCGCAAACACAAGAAAACTAAAACCGAAGAACGGGCAGACCGGATTGCAGATTTAGCTCTTAAGCTGGGCTTGCCACGAACTGCCTTGGATAAAAACGCGGATCTGCAATTTTTGGTGGATAAGTACAAGGAAATTGAGCCAACTGTCACACCTTTTAAAGACCCAGACCCGTTCCAAGAATTTACTTATCCCACTGTATTATTCGCTAAACTGGCGATTTCAGATTATCTCGCTAAACCTTTGGCGAAATTATCCACTGAACAAATTGCCTTTATTGATGGGCTGCTAGCTGAGACTTTGAATAAAAAAGTGATTATTGAACGAGTACGGCAGTATTTCCACTCGAACAAAGGAGGGCAGCAAAATGCTCACTGAAGTAATGGAACACTTTCGTTTGGTCAAGGAATTTCCCAAGGCTGGTTACTACGAAACAGACCATCAAAAGCAAATGTTCAAAGACATTAAAGCTGCCATCCATTCAGGGAAACTGATTGCCATAACGGGAATTATTGGGTGTGGCAAGACGACTACTTTACGACGCTTGTTTGATGTTTTGGAGAAAGAAGGTAAGATTCTAGTCTCGAAGTCCCTTTCTGTAGATAAAGAACGGGCGACACTGCCAACACTTATTGCTGCTTTATTCTACGATTTATCCACAGATAAGGAAATTAAAATCCCTAAAGACGGTGAAAAACGGGAACGGGAACTACGCGACCTGATTAGAAAAGGTAAAAAGTCAGTAGCACTGTTTGTTGATGAGGCTCATGACCTTCATTACAGTACCCTGACGGGACTCAAACGTTTAATCGAAGTAGTTGAAGACGGTGGTGGCACACTTTCAGTGGTGCTGGCTGGTCATCCCAAACTGAAAAATGATCTGCGCCGTCCGACTATGGAAGAAATCGGTTATCGAGCAACAGTCTTCTCCTTGGAAGGCATTGTTGGCAATCAGCGAGAATATATTGAATGGCTAGTATCTGAATGCACTATCTCTGATACTCCAATTGGTGAAATATTGGAGGCGGAAGCTATTGAATTACTTGCCACGCGGCTCTTGACACCACTACAAATTGAGCAACATTTGACACTAGCTTTGGAGGCGGCGTACCGAGTCGCGGTCAAACCTGTGACTACGGTGATTGTGGAGTCAGTTCTGTCAAAGCAAATTGACGATTTGGAACCCACTCTCACAAGGCATGGCTATGACGTGAGGGGCTTGGCGGAACAGTTCAATGCCAAGCCGGCTGAAATTAAATCGCTGTTTCGCGGACAACTTGATCCCACTCGTGCGCGTGAATTACAAGAGCAAATGCTAGCTGCGGGGTTGCCACTTTAATTATTGGTCATATTTAGTACATTAAATCTTTTTCATCTCGATACTCTTGCAGACAAGCATACCCACCGCTTTATCTGCATCTGGCTTATTTGCAATTAATTTGAGCCAAGTCGGATGATTGCAAGCCCGTTGCAAATAATAATGAGTCTGTTTGCAATTAATGTGAGCCGAAGTGTAATCTTATTTGCAATTAATGTGAGCCAACAATTTTCTTGTTTGCAAGCCGGAGCGTTTATGTTTGCGAGCCGCAACATATAGCGTTCCAAATGAATATCTTGGCTGCGTCGGCATAGTTGAGCGCTGAGATTACGAAGTATTAATAATTCATAAGTACCTGCAAGTATAAACTGTACGCGAGTAATATTAGCTAGCGATTTAATACAGTCAGTTTGGTCGCGTAATTTCCGCCCACTAGCAACCTTGCTCAAGTTTTGTGCCTCATCAATATAAAAAACTTTGAGTCTGCGGTGACGTAATGCACTTTCAACAGACATCCTCAACTTTAAATTGGTCATTCTCTGAGAAATTGGTAATTCAATACATGGGTCTTTTAATACAGTTAAAGCACGTAAATAAAAATCTTTCCAATCAAAATTGCTGAACTCAGGTGTAACTGTTTCGACACCAGCAATCGGGATAAAACCTTTATCTCGTTCCATATCTGGTCGCGTTGCTTCTAGCAACTTTTGAGTCATACGACGTAGTAAGGTAGTTTTACCAACACCTGTTGGCCCGAACAAAAACATGAGTGAAGTTGCAGCAGGCTCTTCAACAGTGAGCATGAGCTTTTGCGAGGCTGACAGCAATTTCGGATGCGCCATTGTGTAATTTTTAAAGTAAGCAATCCTTTCAGGAATAGATTGCTCAAGTAGTTGCTTAGGAAAGCCTTCTTCGTCACTCATCAGAACTCTCCATAGTATTCTAGGGATACTAATTTAGTATCTTTTATGTCCATTAATTGGTCGGTTTCTAAATAATTATTTTCCGATTCAAGCAAATTAACTTCAGATGAATTATTCTCAAAATCTGAGTGAAGCTGATCAGAAACACATCTAACTTTAGACGGGTCTTCAATCAGTTGTAAAACGCTTTTATTCTCAGCATTTTTTAGACGCTGTAATAGGAATTTTTCTTCTGTTAACTCAACAGAGTTAAGGAACTGAACTAACTCTCGGTCTGAGTTAATAAAATTATGCCCTTGTAGTCGTTTGCGAGCTAACAGTTCTGCACTAACTAATTGAATTTCCTTTTCTGAGCGTCCTTTAAAGTATTGGTAGTACTTTGAGATACACTCTACCCATTGTCCCTGAACTAAGGCATAAGCAATTCCAGCATCCCAGGGGTCATATCTAACATCAACTGATGTGAATTCAATTTCCGGATTGCGGAATTCATTATTCCAGTAGTAAATGTTATGAATTTTCACTCCCTGACCTGGTTGGACTTTGCGTTTACTTTGTTGGGGCGCGGGTAAAGTGAGAATACGAAAGATGTTGTCATATTCTACTCGTCTGTGCAGTCTGCTACCACCAAATGCAATTCCGACATTGAAGGCATCACTAGGTGTTTGTCCTAGTGCTGGAGGTTCGCGTTGGTCATATACCTCGTAACCCCACGATAAAAGAGCCGAATATAAGTCAATTAGCGTCCACACTGCCTGTTTTGAGGGACTAACAGATTTAGTCACACATCGGTGTTTTTTTGTAAGTTGGGTATTGCCAAGCAATTCATAAATCAGTTGGGTATTGGCAGTTCCAAATAGTCTTTCCACGACTGAGCCGAATCGAGGATAAGCAGGTGGGCGATGTTTTTTGGTACAAGCATAAGTTGCCAAAAGTTGCTCAAAATAATGGCTGTGGAACTCGGCACCATTATCTACAACTATTGTTTGTGGAAATCTCTTGAACCTCATCACGCAAATGCGGATGACCATCAATATTGAACGGTAACTTGGCTCTTCAAAGGTGAGATATATCGCTAATAATCGTCGGCTATAGGCATCTACCATGAAGGTGGCCCACGGACGACCTAAATTTTTATACTTAGTATCGCCAATATCTAAATGGCAATTGCTCAAGTTTTGCAATGAACTTACTAATTCAATGTCAAGTTGAGTATGGTCAATGTGAACTATTTCAAAAGGACGTTCTCCGTGAGTTGGAGTTGTTAACTCTAACTGCCAATCGAAGTCTAATTTTTGTATTGCTGCTCGTCTTCCCTGACGTTTTAATGTCTGCTCATAACCCGAACGACGTTGAATTTCCAAACAAAATCGATTAAAACTAGGTGGGTTAATTTTCGGAGATTGGGATTCACAGGCAATTCGGAAAGATTCATAGACCCTGAGTCGCCCTCGTTGTTTAAGGGTTTCGTAGTTCTCACTAATAAATGTAGTCATGAATTCCTGTACCCGCAGGTCTAGTCTTGGCTTGTAATTACCTTTGTTAGTGTTTTTGGGCAATAATCCTACAAAACCATTGCCATAAATTTCAGTTGCTTGTTGATAAGCTTTACGCCAGCGCCGAATTGTGCGGGTAATTCCCACTGGAGGATGGCTAGAAAGGTAAGGCGATAATTGAGTGTAGCGGTGATTAGCTTCTACAATATCTTGCGGTTTCGCGTGACGCAGTAATTCCTCTAGCTGCTGTTGTTTTGCTGTACTTTGAATAGGTGCAACAGTTATTTTACCGTCTTGGATCAGTTGAAAAACTGTAGCATTTGGCAGTTCTACAAACTTCCCATCTGTCCTGAGTAATCCTGTTGTTGTTGTTCCTGTGTTTACAACATCCCAGGATTCACCATCCCAAGACAGAGATTTACCAACCGCAATTTCAACGGATTGAAGGTTGCTAGGTATACTACTTGGCTTGACGGATGTTATTCGTTCGTAAGCGAGTGCTATTTCCCGGTTGGCAAAAACTTTTACTTGTTCAGGTTCGGATAATCTAGCTGTATTTAAGTTGACATAGATTTGCTCAGTTGCAATTAAAGTATAAATGTCATCTAAGCTGGCTTTTTGGTATGCGATTTTAATCAAATCCGCTAACAGTATGCCTGGATTTGTTTTTACTATCGCTAATACTTTTCTGATTACTTGATTATCTACTGCAACTGGTTCTAGATTCAAGTAATCTTCCAACCAGATAAAGTTCTGCTGAAATATCCAGCAAATTAAAGCGCTCGACCACACCCGGAACTCAAGACCAAATTTCTGTGCATAATTTTCTCCTGGTGGACATCGCCAAATACCATTTTCGTCTTGTTGATAGCGGTTTGGGCTTGCAGCAGAAAGTTTTACTAATTCTTGTTCTGATTTACATTCTTCCCAAAACGCTGAGTTATTACTGATAATAAAGAAATCAGGTGTGTATAGATGGCGGTTGTTTCTACCACTTAAAGATTGATAACAAAGTTCAATAGCTGGTGGTTGGTCGTAATATTCCAGAACATCTGGGTTATGTTCAAGTTCGTATATCCTAGCTAATTCGTGCCGATGAGACTCAAAACTTATTGTTACCCCCATTTTTCTGCTAGGGTAGAAACCAGATACATTTCCTCTGCCACCTTGGACTCGCCGTGATGGTTTTTCTGCACGGATTTGTCTGATTACCTCACTTGCCGATTGACTTAAGTTGAGGCTTTTACACCAGTCGCCAAATTCTTGAGAGTTCATCATGAATTCGACCTCAACTTTCAAATGAGTCAGTTGCTTAATTCTGATTCTAAATTTATCTAAACACAGGTGGTGATTTGCTAATATATATTGATTTAAAACTTTAAGATTGCTTATGTAAGTACAACTAGTGGACAACTTTCAGCTGATTTTTCAACTTGGTGACAATTTATGCTTTGATTTTTGACTTTGAGACAATTTTTGGCTGTATTCGTCTTATGGCATCAGAAATTTTCCTACGATAGTATCAGTGTTTCGCCTTCGATGCGGACAACTTATGCCTTGTCTATTGGACATATTGTGCTTAAAGTTACATATTTTCAAGTCGCAAGTCGGAGGTCGCAAGTCGCAAGTAAGAATGAAGAGTGCTGAGTTGAAAGACTGCCCACAAGGGACGGGGCATTTACCGAGTGTGGAAGTACCGAGTATGGTAAACAGAAGTAAAAAAGGTAAAAGCAGTGAGTGAAAATGGAGACAAAAGCATTAGTATCACTGACAGAACAAAAGCTTTTGCAATTAGAATTATCAAAGCTTGTAGCTTTCTTGATGAAAAACCGGGTGTTTGCCGTACCCTTTCTAAGCAAATGTTACGTTCTGGTACCAGTATTGGTGCTAATGTACACGAATCTCGTTCGGCTCAGTCTGATAAAGACTTCTTGCACAAAATGGAAATAGCTCTTAAGGAAGCGCGCGAAACTGAGTACTGGTTGGAAATTTTAATTGAATCTGAAGTTGTTGAAAAAGGTAAATTTGATTCGTTGCTTCAAGAAACTAAGGAAATAGTGAGGATACTCATTGCTTCAACTCGTAAAATTAAAGAGAGATTGAATGGCAGCAAATCCAACGGCAGAAGGATGGAGATGGCAAGCGAGAATTAATAATTTAACTCTGAATAGAGAATAAATATATTTTCATTACTTGCGACCTGCGACTTACGACTTACGACTTGCGACTTGCGACTTGCGACTTGCGACTTGCGACTTGCGACTTACGACTTACGACTTGCGACTTGCGACTTGCGACTTGCGACTTGCGACTTGCGACTTGCGACTTACGACTTGCGACTTGCGACTTGCGACTTGCGACTTGCGACTTGCGACTTGCGACTTACGACTTGCGACTTGCGACTTGCGACTTGCGACTTGCGACTTACGACTTGCGACTTGCGACTTGCGACTTCCTTAAAACTATGGCTCGTGATTTATTCCACAATATTGTGAGGTCTGCACTGGAAAAAGATGGTTGGTTAGTTACAGATGACCCACTAAATATTCGGTGTGGTGGAGTTGATGTTCAGATTGATTTAGGTGCAGAACACCTAGTTGCTGCCCAAAAAGCTGGAGAAAAAATAGCAGTTGAAATCAAAAATTTTGTTAGTGCATCGAAGATTTCAGAATTTCACATGGCACTAGGACAATTTATTAATTATCGGACTGCATTACGTGCAGAAGAACCTTCGAGAAATTTATATTTAGCTGTACCATTGGTCACTTATAATGATTTTTTTAATTTGCCTTTTATTCAAACTGTAGTCAACGAAAACAAATTGAAGTTAATTATTTATAACCTTGAAACTGAGGAAATAGATCAATGGATAAGTTAAATGAATACCGCACAAAAGTTAAGCAATTATTAACTAAGTATATCGAGTACAAGCCTAGTTATGGAGATGTAGAAGTCGAACAGATTTTTGACGTAGAGTATGACCATTATCAAATTATTAGCATTGGATGGAACAATCAAAAACGGATCTATGGCCCAATAATGCACCTAGATATCAAAAATAATAAAATTTGGATTCAACAAAATACAACGGAAGTAGATATTGCTTTAGAATTGATAGGAATGGGTGTACCTAAACAAGATATTGTTATCGGTTTTCATACTCCTAAAATGCGCCAACTATCGGAATTTGCTGTGGAATAAACATGATGCAAAATGCAGAATCTTTGCCACTATTTCGATTGAGCATATATTAGTCAATAGAGAGCTATGAGGTAGCAAAAGGATTACTTTACGTTGTATAAAATCGTGTAAAATTTTGTTGTGATAGCCACAAGTTGTCAATCATGCTTTATTACAAACTAGTAGGACATACCCCTGTTGCTGTTAATTCGTTGTCAGAGTGGCAAAATTATTTACACTCAGTACAAGATTCACTCAAACATCTAGTTGCCGAAACTATAGTTGGGGATGCCAAAGTATCAACTAGTTTTTCGGGATTCGATCTCACTTTTGGAGATCCCCCGTTGCTTTTTGAAACGATGGTTTTAGGCGGGCCTCATCACGGGAGAATGCAGCGTTATTCTACATGGGAGCAGGCACTAACCGGTCATAATCGTACCGTCGTAGAAGTTATGACTACCTCACCACCAGATGAGTAGTCTCAAATCAATACAATATTTAATACTTAATACTTAATAATTTACACAAAACTGGATGAACTACAGCGCAGATTCTTTACCTGAGATCAAACTCATTCCCCTTGATCGTGAAGCTCTACATTTCACACAGCTAGGAGAAACTAGAAGACCACCAACCGATATCCGGTGGGTAAAAGTACTGGAATTTTTACGCAGCAATAATCTCGCACCCAACAGCCGCAAACTCTACGAACGCGAACTCAAAAGGTTTTTGGCTTGGAGTGAGCTACATTATCATGAACTGCATCCACGTCATCTTGCGCTATATAAAGAATATCTCCGTGATGAAATACGGACTGATGCAGGTAAAGCGCTTTCAAAAAGCAGCATCAATGCGGGAATTGCGGCACTCAAAAGCTTTTTCAAATGGATGTGTTACACGTATCCTGAAATTATTGCTACTAATCCTACACTAGGGATAAAACTGGAAAAAGTACCACTGCCACCAGCCCAGAGTTTAACCCCAGAACAGATGGAACAGGTTTGGTCAGCGTTGGAATTGCTGGGAGAAACAAAGCAACGGGATACAGCACTGGTTCACATTCTCAGTCATGGACTCCGGGCAGGGGAAGTTGTACAGCTAAATGTTGGGTCATTTGATGGCAAGCTGCTATTTTTACCAGACACCAAAACCAATGAACCACGCTTAGTTCCACTGCGAAAAGAGAGCCGGGAAGTTTTAGCAGAGTATTTGCTTACGCGCGAACAGCAGGGAGAGATTTTGACCAGTCTTAGTCCATTGATGATTTCACACCATGCTTCATACAAAGGTGAACGCTTGAGTTATCACGGGATTTATTTCGCTGTAGAAAAAATTGGTGAAATAGCTCATATTGAGGATTTGCACCCTCACTCCTTTCGACATACTTACGCTACTGACTTATTGCTATTGGGAGTTGACCCCAGCCATGCACGAAAATTAACAGGACATCAAAGCGAGAAAGCGTTTCGGCGCTATACGCTTCGCAGCGAACAAGAAGCAGCGATCGCTGCTTACTATCGTGCAATCGGAGAGGAAGTGGAGTAA

Protein sequences of DBSCAN-SWA_1

>NZ_CP046705|70364:87092|84100_84520_+|WP_114080969.1|DBSCAN-SWA
MSENGDKSISITDRTKAFAIRIIKACSFLDEKPGVCRTLSKQMLRSGTSIGANVHESRSAQSDKDFLHKMEIALKEARETEYWLEILIESEVVEKGKFDSLLQETKEIVRILIASTRKIKERLNGSKSNGRRMEMASEN
>NZ_CP046705|70364:87092|73198_74257_-|WP_114081264.1|DBSCAN-SWA
MLDNLEFNNWCRQQDLSQAGQAIIEEIRSSNPSRRVTGARKNVCGSYPSRKMGCTIQFESHHNELARIYELEHDPCVLEYYDQPPAIELVYQSKSGRKNRHQYTPDFFIIRTDSAFWEECKTELELNKLNELNPNRYCKNSDGKWHCPPGEEYAHGHGLDFHVWSDALINWNFQQNLIWLLDYFGYSSEIIDETEQSLIVNTVNNHLGMTLTELLKNEEINPDVLYWLIATDKLYVELNKVKLSQPETVFVFINQNVALSYEHLNSIESTTQTSNQILLQIAVGTNIYWDGESWEIVNTGTTTTGLLRADGKLIELPNLAFTALIDTGKIVGDKTTQTSNIKISRWLQLNIR
>NZ_CP046705|70364:87092|74643_75546_-|WP_114081263.1|DBSCAN-SWA
MPVENLKLYQSWELEQPILPERSRLFSLPPVGVGTAIVESLSSYLIRLADAHGITVGGLIRYYIAPLFFLNEQPPGLSKKDAIELVVVRLRKELAILQQPTAQFWLSQTQHVSKVVNVLEILTGRKDISYLTLLPWKTWRLSFNHIFHTQQRWCAGCYQDWRDANTPVYQPLLWALEPVTVCPYHQRYLQIYCLCYGHTQPFFQPQKLNGYCHECDAWLGRNLDLPSHSRSKGRKFDRDLWIAQALGNLLAATPSLHTNPLIRETKVTPKRTLPTLYKFLRWCYKLSLSPVEGLNLLEIQ
>NZ_CP046705|70364:87092|84831_85245_+|WP_114080970.1|DBSCAN-SWA
MARDLFHNIVRSALEKDGWLVTDDPLNIRCGGVDVQIDLGAEHLVAAQKAGEKIAVEIKNFVSASKISEFHMALGQFINYRTALRAEEPSRNLYLAVPLVTYNDFFNLPFIQTVVNENKLKLIIYNLETEEIDQWIS
>NZ_CP046705|70364:87092|77361_79008_+|WP_114081251.1|integrase,transposase|DBSCAN-SWA
MPAEALTNLRHRLDMLPSRCQERRQLMEETASLYGVSIDTLYRALRNSSRPKSINRSDSGTPRKLSQAEMELYCEVIAATKIRTCNKKGRHVSTARAIELLEDFGMNTPQGFIKPPKGLLTKATVNRYLKTWGYDHLTMTRQPPAVRFQATHSNECWHFDLSPSDLKHVKQPLWVETGKGNPLLMLYSVVDDRSGVCYQEYHCVYGEDVTAALRFLFNAMTASTSDGCPFQGIPEMIYTDNGPIAKSHVFQNVMDCLGIKLASHLPAGKDGRRVTARSKGKVERPFRTVKEAHETLYHFHEPENEVEANLWLRQYLLNYNDQKHRTEAHSRLEDWLRNLPKSGIRQMCSWERFCTFAREPQRRKVDATARVSVEGVAYEVNPDLAGETVVLWWGLFDNELYVEKGDQRYGPFYPVDGPIPLHRYRKHKKTKTEERADRIADLALKLGLPRTALDKNADLQFLVDKYKEIEPTVTPFKDPDPFQEFTYPTVLFAKLAISDYLAKPLAKLSTEQIAFIDGLLAETLNKKVIIERVRQYFHSNKGGQQNAH
>NZ_CP046705|70364:87092|85232_85568_+|WP_114080971.1|DBSCAN-SWA
MDKLNEYRTKVKQLLTKYIEYKPSYGDVEVEQIFDVEYDHYQIISIGWNNQKRIYGPIMHLDIKNNKIWIQQNTTEVDIALELIGMGVPKQDIVIGFHTPKMRQLSEFAVE
>NZ_CP046705|70364:87092|70364_72146_-|WP_114084686.1|integrase,transposase|DBSCAN-SWA
MPLSVLYLIVPSYLAAAEIIKHATCEDIIEANRRYNLIQPYLEDALKAYPSSTIRRWRTQYQKALLIYGQGYLGLLPKHNNKGNRTPKIDSQTQEFMLDFIKEHYETPKQRRKIRVYESFVLACQTHDPPFKPPSRITFCHAIKQRSGHHQTRKRLGNRAAISEEPFYWELKQTTPRHGSRPFEIVHIDHTQIDIELVSSLESLTNCHIATNNSIHQNLGRPWATFMVDAYSRRILSVYLTFDEPSYRDCMMVIRICVARFGRFPQNIVVDNGKEFHSHYFEQLLASYTCTLKYRPPAHARFGSIVERLFGTANTQFIHELQGNTQIKRLHRKVTKSVSPERLAIWTLEELYSAFCEWAYSVYDQRLHPALGTSPCDAFVTGLATGGSRLHRRVAYDELFQILTLPAPDQRKRKVQPGKGVKIHNIYYWADVFRDPEIEKSMLWVRYDPWNAGIAYALAQGQWVKCISSYYQYFQGRSEKEIRLASAELNQRQRNYGRKLTINDRELVEFLNSKFAQEGAILKQRLRDTEHDKVHKIIQNNLITEPKLNLAEFAAEENNDCLGDDSTNEGKNCETISNLTAYITETLEYYGEF
>NZ_CP046705|70364:87092|76235_77075_-|WP_114081250.1|integrase|DBSCAN-SWA
MRIIRQLLLWIVEHPGSGGDFQPEQLTKTAMEIYLAYLDTSGYSIAHQARVKSAVSGFARWLIEEKGILRRNPTRGLNIPAQPLLAPRQLTPDQRYILRNLIEKDGHPRSMAVFALGYWAGCRVSDVSWLRIEHTHIGPKVGWLHVGYKGGKARDIDLINAVRKPMYEYIHHGGRDTESDYTFTSQRNERLTEAGIHRWWKNIKAQATVSEWELIHDVTFHDLRHDFAHRAREAGWTLEEVAYYLGHITKKGTPAIQTTVRYTQSSRQQVKDKLALLKG
>NZ_CP046705|70364:87092|72232_73170_-|WP_114081710.1|transposase|DBSCAN-SWA
MSAPLRVRLTDLEDLTLLELRSATTVPQRTRERAHIIRLNAQGWNVPAIAKIFECHEHTVRATLRRWENKGLGGLWETSGRGAKCKWLEADLAYLEDCLEVEPRTYNSLQLSEKLAQDRNVQLSPSRLRRLLKKKWKWKRTRHTHKRKQDPEKRRIKQADLDTLKQAAVEGYVELKYLDESGCCRWSPVSYSYSRIGSQKQMAQVGSRGGRISILGLWQPQVSFEYALVQGGFKTKRYIEVMDWVAAKAQNTLVETGRISVIVHDNGSLHTSKKAKQKWLEWQEKGLFVFFLPPYCSEMNDRGRVASTKNS
>NZ_CP046705|70364:87092|80870_83645_-|WP_167756037.1|integrase,transposase|DBSCAN-SWA
MMNSQEFGDWCKSLNLSQSASEVIRQIRAEKPSRRVQGGRGNVSGFYPSRKMGVTISFESHRHELARIYELEHNPDVLEYYDQPPAIELCYQSLSGRNNRHLYTPDFFIISNNSAFWEECKSEQELVKLSAASPNRYQQDENGIWRCPPGENYAQKFGLEFRVWSSALICWIFQQNFIWLEDYLNLEPVAVDNQVIRKVLAIVKTNPGILLADLIKIAYQKASLDDIYTLIATEQIYVNLNTARLSEPEQVKVFANREIALAYERITSVKPSSIPSNLQSVEIAVGKSLSWDGESWDVVNTGTTTTGLLRTDGKFVELPNATVFQLIQDGKITVAPIQSTAKQQQLEELLRHAKPQDIVEANHRYTQLSPYLSSHPPVGITRTIRRWRKAYQQATEIYGNGFVGLLPKNTNKGNYKPRLDLRVQEFMTTFISENYETLKQRGRLRVYESFRIACESQSPKINPPSFNRFCLEIQRRSGYEQTLKRQGRRAAIQKLDFDWQLELTTPTHGERPFEIVHIDHTQLDIELVSSLQNLSNCHLDIGDTKYKNLGRPWATFMVDAYSRRLLAIYLTFEEPSYRSILMVIRICVMRFKRFPQTIVVDNGAEFHSHYFEQLLATYACTKKHRPPAYPRFGSVVERLFGTANTQLIYELLGNTQLTKKHRCVTKSVSPSKQAVWTLIDLYSALLSWGYEVYDQREPPALGQTPSDAFNVGIAFGGSRLHRRVEYDNIFRILTLPAPQQSKRKVQPGQGVKIHNIYYWNNEFRNPEIEFTSVDVRYDPWDAGIAYALVQGQWVECISKYYQYFKGRSEKEIQLVSAELLARKRLQGHNFINSDRELVQFLNSVELTEEKFLLQRLKNAENKSVLQLIEDPSKVRCVSDQLHSDFENNSSEVNLLESENNYLETDQLMDIKDTKLVSLEYYGEF
>NZ_CP046705|70364:87092|85702_86026_+|WP_114080972.1|DBSCAN-SWA
MSIMLYYKLVGHTPVAVNSLSEWQNYLHSVQDSLKHLVAETIVGDAKVSTSFSGFDLTFGDPPLLFETMVLGGPHHGRMQRYSTWEQALTGHNRTVVEVMTTSPPDE
>NZ_CP046705|70364:87092|75535_76018_-|WP_147262468.1|DBSCAN-SWA
MFASRNSYKADNSEDLRAFQGIVQTFQRHLPLQIEPDLLKHWDFCYERCVGCIGILKDWLSRALFSALLKGDKTLTFSDLESHALKTEQCIILLNEALHGEEQLNSRRDTNALRAALGLEVATDVTPKTLQTSAKQTRRHAAVGQPLPQRRPVGGGHNAC
>NZ_CP046705|70364:87092|86081_87092_+|WP_114080973.1|integrase|DBSCAN-SWA
MNYSADSLPEIKLIPLDREALHFTQLGETRRPPTDIRWVKVLEFLRSNNLAPNSRKLYERELKRFLAWSELHYHELHPRHLALYKEYLRDEIRTDAGKALSKSSINAGIAALKSFFKWMCYTYPEIIATNPTLGIKLEKVPLPPAQSLTPEQMEQVWSALELLGETKQRDTALVHILSHGLRAGEVVQLNVGSFDGKLLFLPDTKTNEPRLVPLRKESREVLAEYLLTREQQGEILTSLSPLMISHHASYKGERLSYHGIYFAVEKIGEIAHIEDLHPHSFRHTYATDLLLLGVDPSHARKLTGHQSEKAFRRYTLRSEQEAAIAAYYRAIGEEVE
>NZ_CP046705|70364:87092|78997_79969_+|WP_114081249.1|DBSCAN-SWA
MLTEVMEHFRLVKEFPKAGYYETDHQKQMFKDIKAAIHSGKLIAITGIIGCGKTTTLRRLFDVLEKEGKILVSKSLSVDKERATLPTLIAALFYDLSTDKEIKIPKDGEKRERELRDLIRKGKKSVALFVDEAHDLHYSTLTGLKRLIEVVEDGGGTLSVVLAGHPKLKNDLRRPTMEEIGYRATVFSLEGIVGNQREYIEWLVSECTISDTPIGEILEAEAIELLATRLLTPLQIEQHLTLALEAAYRVAVKPVTTVIVESVLSKQIDDLEPTLTRHGYDVRGLAEQFNAKPAEIKSLFRGQLDPTRARELQEQMLAAGLPL

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
68717:68731	attL	NA	NA	NA	NA
WP_114084686.1|70364_72146_-|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_114081710.1|72232_73170_-|transposase	IS630 family transposase	NA	NA	NA	NA
WP_114081264.1|73198_74257_-	hypothetical protein	NA	NA	NA	NA
WP_114081263.1|74643_75546_-	TniQ family protein	NA	NA	NA	NA
WP_147262468.1|75535_76018_-	hypothetical protein	NA	NA	NA	NA
WP_114081250.1|76235_77075_-|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_114081251.1|77361_79008_+|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_114081249.1|78997_79969_+	AAA family ATPase	NA	NA	NA	NA
WP_167756037.1|80870_83645_-|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_114080969.1|84100_84520_+	four helix bundle protein	NA	NA	NA	NA
WP_114080970.1|84831_85245_+	fatty-acid oxidation protein subunit alpha	NA	NA	NA	NA
WP_114080971.1|85232_85568_+	XisI protein	NA	NA	NA	NA
WP_114080972.1|85702_86026_+	hypothetical protein	NA	NA	NA	NA
WP_114080973.1|86081_87092_+|integrase	site-specific integrase	A0A1B1P7C7	Bacillus_phage	2.4e-12	27.1
89541:89555	attR	NA	NA	NA	NA

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NZ_CP046705|112551:178095|DBSCAN-SWA
GTTAAAGATCCATCAAGTTTAAAGCGCTACTGTCATTGGGTCTAGCTTTGAGATAGCGATCGGTGATGGCTAAATTGGCATGACCCAAAGTTTCTTTCACCAATACAGGATTAGTCCCGCGCTCAATGGCGTGAGAACCGTGAGCATGACGTAACCAGTGAGCAGAAACTAGTTCGCTTAATCCAGCTTCTTGTGCAATTGCTTTGACAATCGGGTGCAAGTTTTGACGGTCTAAATGTCCCCCTTTTTGACTTGGAAACACTGCTTGATTGGAGTGAGCCGAAGCTTTGAACTCCATTAATTCCGCCCAAAGCTTTGGCTTGATGAGAATTGTCCGATTTTTGCTGCCCTTGGCTTTTCGCACGTAAACTTGACCACTCTCACCACGGGGTGTCAAATCTCCCCAAGTCAGATCACAGATTTCACTTGCCCGTAACCCTGCCTGATACAGGAGTTTGATAATTAACAAATTTCTTTTGGCTGTGTACTGGCGCTTAGGAGTTTTAGCATCAGTTAAATGCTTAGAAGCTGCTCTTACCAACAATTTAATATCAGCTTCGTCTAAATAGCGTTCGTTGATTACATCCGGCAGTTCACCGAGTTTTAGCGCCATACCCACATTAAAAGGGAGATATCCAATTTTATGACCGAAACTAATTAAGCTTTTAGCTGCGGCAATATATATCCGCTTTGTACTTTCAGCATTGCCCCCAAAACAACTGGCGTATTCTACCAAGTCTTCATAAGTCACTTTTTTGAGAGGTTTGTCCAAAAATTCCAGAAATCGCCTAATGTAGCGTCGGTAAGAGATGATAGATGACTCTGCTTTTCCTTCCAACCACAGCGCAATCAACTTCGCCTCCGCCTGCGCTACTGGCAAGGAAGCGATCGCCTTTCTATGCGCTGTTATGTGGACAAGAGAGAGCGTCATTTTTATTACTCCCTTAATAATCAGACACAAGTGTAGTTTCGTCTGGTTTTATAGTGTCTGATTTTTATTGTCCTTTAAAATGGGCGTTTCAACTCACTCTCAAGCGAATGAAAATTTCTCGATTTTTGCGTATAGTACACCTCTAATACTGAGGAGCGTGACAAACACAATACTGTTATGCAATTGTTCAGCAGGGTATTTATTTTGAAAAGCCTAAAATTAGGTGAAAAAAATAAACTAAAAATGACTTTATAGTTAATAAATGATATAAGAGGTCAAAGAGCGTCCTCCAAAGTTTATTTACGCCGCAGTGTACTGCTTTTTCAGCGCTATCACGCCATAAAACTATAGAGTCATTTTTAGTTTATTTTTTGAGAGTGGTTTGATTGCTTTGCTTTGTGTTTAAGACACTTTTTTTATAGAACCGCAAACGGGAGCTAGAGAAGTAGTTTCTCAAGAATTGCCAAGGCACTTACCAGTAATGAAATGCCCCGCCGTCGATTACGAGGCAGCAGGAAAAGGTACAAACCGAGTGGAATTGTGGGCGAAAGCACAGCTAGCTACCAGATTTCTCACTCTTGATTGAGAGCAACAACCGCAAGGCGGGTGAAATTGTTAAGTTGAACATTTCTAAATTGCAATCGTCGGGTGCAAAAAAGCGCTTTCCAACCGCTGCTGTAATCGCGTATATCGCAGTTGGCCGTCACTAGAACGCAAAGCCTTGGATATCGCTTTCTTGGAACCAACGACAATCGCTAACTGCTTGGCACAAGTTAATGCTGTGTACAACTGTTTACGAGACAACATCATATAAGGCTGCGTATAAATTGGCAGAATTACTACCGGATATTCTGAAACCTGGCTTTGATGAATGGTGAGGGACCAGGCGAGGGCAATTTGATTTAAGTCTGCTCTGGTTCTAACGACAGTATGCTTACGATACTGTACAGTAACTTCCATCTCTTCAAGATCAATGGCCTTGATAATTCCGAAGTCGCCATTAAAAATTTCGTGATTATAATCATTAGTCAGTTGAATGATCCGATCGCCTTCTCGTAATAAATTCCCACCTCTGGTAATCTCTACTTTGTCGGGACTGGGCGGATTAATCAACTGCTGCAATACGGTATTGAGGTTACGAGTCCCAAGCAAACCCCGCGACATGGGGCAAAGCACTTGCACATCAGTAGCTAGATTGTAACCCAGGCGGGGAATCAAGTCTGTAATGATTCCGGATATTGCTTTAACACCATGTTTGGGGTGATGACCGCCGCCATGCCACAGACACTCAGACACGGGATTATCGGAAATCGGTTCAATAGTGGGAAACTGGCTTCGGTTAATTTGGTGAGCAGCGGTGATAATTGCGCTCTGTTGGGCTTGCCTAAATACCTTGGTCAACCGCACCACCGGAACGTGACCAGAATTAATCAAGTCAGCAAGGAATTGACCGGGACCGACAGAGGGTAACTGGTCAACGTCACCCACTAGCAGTAGTTGGGAACCGTATTGTATCGCCTTTACCAAAGAAGATGCCAGAAACAAATCAAGCATACTAGCTTCTAGCGCGACAATTGCGGTATGGGGTAAAGGGTTTTGATTATCGCGTAAGAAGCCCATTGTCTTTGGGTCAAATTCCAACAAGCAGTGTATCGTCTTGGCTTCGAGTTGTGTGATTTCACTCAGGCGTTGAGCAGCGCGTCCAGTTGGTGCAGCTAAGGCGATAGATTTGCCCATTGCTTTCCACAGAGAGACTATGGTGTGGGTGGTGAAAGTTTTACCGCAACCGGGGCCACCAGTAAGAATCATTACCCTTGAATATGCAGCCATTTCTACCGCTAGCCGTTGCTGTGGTGAAAGTTTGATTTTATGACTCTTGGTGAAGCGCTCAATCCAGGCGCGAACACGAGGCATATCTTGTGCAACTGGTTGGCAAAATCTAGATTGTATTAATTGAGCAAGGTTCTGTTCGGTGTGAAAGTAGGTTGGTAGATAACATAGCAGCGTTTGGTCTTCGCTTTTCTCGCGGATTAAGTCATCCTTGAGTGCCATGTCTTTGATAATATCAGCGAGGGCATCTTCTTCGGGTGTGTGATCTGCTGTAGTCAGCAGTTTGATAACATTCTCAATTAGTAGAGACTGGGGTAAATAGCAATGCCCATCGGCAGCAGCTTCGTTCAAAACATGAATTAAACCAGCACGGTAACGGAACTGACTATCAGGTGCAACTCCTAAATTAAAGGCAATTTTATCAGTTCTCAGAAAACCAATACCGTAGATGTCAGCAGCTAACTGGTAGGGATTGCTGGTGAGAGTAGCGAGTGCTTCATCCAAGTAATGCCTGTAAATTTTGACTGCATAAGTAGTAGAAACGCCATGACTGTGGAAAAATAGCATTAAATAGATGTAAGAGATGTAAGAAAATAAAATAAAAATAAGTTGATAGCTAAATAAAGATATTTTGAATTGAAGCAGAGACTTGATATTTGGGTTATGCCATCGGCGACGGCGACCCGGACGCGAACAATCCCACAAACTATCGAGTTTGCCCCAGTACCAGCGATGAATTGTGTCGCGTACAGTCTGTGGATGCCATTTTAAGTATTGTGCGATCTTTAGCACTGTCCATCCAGCGGCTGATAAGCGTAGTACAGTGGCACGACTTTGAGTTCTTGGTGGTATACCTTTTGCTTGAGTGAGTGCTAGTAGGGCTTGATCTTCTATTGGTGACAGGTCAACTTTTAAAGGCGCTGGCATCTTGGTCAGGGGTAAAAATATTTACGACTAAAAGAGATTATCCCAATTTGATGTGCCATTTTACTTTAATGAATTCTATTTACGAACGCCAAGATGCTCACTGATGACCGAAGGGACTTTAGCGAATGCAAATTAGTTTTTGATGTCAGAAATTACACATATTAATTTTACTTATAAAATAGGTAGCCTATAGCACTTTAGGTTACGTAGCTGCAATTAGCGATCGCTCTTTGAGGAAAACTTTTTGGTTTACTGATAACTATTTTATTGTGTACTTCAAGAGTAGCCTGGTTGGATGCGACCGTAGTTAGATATGAGTAATGGAAAAATCACATATTCAATACAAGTACGTCGGAAAAAGCGAATTGCGTTAGCGACGAACGCGAGTGCGTCTCGCAGAAAAGGAGCGTCACTGTGTTAGCGGAGCGGGGCGTTAGCAAGAGTGCGAATTGTTCGGTCATCCGGCAAGTTAGTCAGAAGCATCCAAATGGTTTTTCAAAGTGTAGGGGCAATCAGGAGTTTTGATTCCACTGGCGTAAGGTAATTTATAGGATGCCCAAAGCTGCCAGCGCAAAACATCAACTCCAATAGTTGAACTACCGAATTGTACTCGAGAGTCTTTATCTGGATTTTGTATAACATTTTTGATGATGGTATTTATCGCTTCTATCTTGAGATTATTCGGTATGCCCATTAGTAGTTTTGTAAGCCACTGTTTGATTTGTGGTGACTGTAGCCAGTCTTTGATTTGGTCATCAGTGGGAGTTAGGCGATTGACTAATAGCTTGGGATTTTCGTTATCTTTATTAACTTGATTTTTGGATTGAAAGAGTTTCTGAAAATTAGCATCTGTGTTGGACATAAAAATAATTGATTAAAAGAGAATATCTCTATTATAGATAAATTGGATAAACCCGATAATAGCTAATATATTTTATAAAAAAATAAGATGAGCAAATATAAAAAATTGATTTACAATGTTAAAATAAATTATGAATATTTGATTAAGTAAGTGTCTTATAATTAAATAAGTTCCTTATGCAAGTATCAAATAAATACTATGCACCCAATAGAGTTTAAGAAGAAGTGGAAATTAACTTATCAAGAGATGGCGTTCGTATTAGGATACGAAAGTTACGATACTGTCCGAAGCTGGTTCAGGTGTGGAAAGAAGCATCGAAATCCAATGAAGGTTGTTCATATAACTTGCTGGCTTTTGAATGAGAAGTGGGAACGCGAAGGAAAAAAAATAGTTGCTTTTTACCTATAAATGTTTCCTAACTGGGTAAAATGTCCCCTTCCCCGCCACGAAAAAGGCGGGTATTTTTATATGTAGTTAGAAGTTCCAAGAAGTTCTCAGAATCATGGGGATAGGGGGGTTTACCTGGCAAAATGAAGAACTAACAAGACCAGAAGTTGCGGCGATGTTAAAGCCAAAGGTTTCTGCAAGACAACTACAAGCATATTTGAACATAGCTCGGAAGTACTTGCCGGAGTTCCAGAAATTCACCAACAAAAAAACAGGTGGTCTAGATGGCTATGCAAAACTATACGAGTGTCACATTACAGTACTTCAGGAAATTCGCTCACTAGCTAGGGAACATACTTTAGCTGACATAGAAAGTGAATTTCAACAAAGAGCATTAAACAAGTCAGAAGTGGGAAGTGGGAAGTAGATTTTTTGTTACTTCCAACTTCGATAATAAGGTGATTTTTAGATTTTTCCTAGAACAATGAAAAAAGGAGTAATTGCCTTGGCATCTAATAATTCTGTGCGAAGAACACAAACTCAAGTTCTAGCTAAGGCGCTTGCGGCGATTGGGCGCAAGTATCAGCATCAAATTTACGCGGCAGGTACGGCGACAATCATTGTCATGCAGTCGATGCCCTCTTATGGGTGGGGCTTATTCGATTCGGCTCAGGTGGCAATGACTTGTATGTTCGGCGGCGCTGGTGGTATTGGTGGGGGTGGTGCGGCGGCGGCAACTACGGCGATTAAAGCACTTCCCGCAGTGATCAATGCAACCATCACAGTGCTTTTGTTTGTATACTTTGTAGCTTCTGGGCTTAAGGTTGCTAACGGCATTGGTGAAGGGCAGGAAGTAACGCAGATGGTTCAACAGCCCGTAGGCGTGTTTTTCATAATCCTGGTGCTTTGGATTGCTCAAAGTATCTTATTTAACGGCGTTACAGCCGCTTGTTAGTGATGAGCGAGTACAATAAATCGCCCATGAAACGGGTGAATCAGTCACTTGGTCAAAATGCAACAATAAGTATTTTTACTGGCTTTCAGTTTGCAGTCGCGTTATTTATGTTTGGCGTGGGCTTCATCATAGCGATTATGTTTGGGGCAGGAATAGTTTGGGGACTGCTGGCTGGTGTTTGGTTGAGTGCTACGGTAATAGTTTTATCTGGCAAACGTCCTTACTTGTTCTGGTCAAGAGTGTTCCCAAGCGTTCCAGTTTTCACTCGTGGCTATGTCAGATATTCTTCGCCCCAAAACAAAAAAAGGGCGGGTTCAAAGGGGATGCCTAAGCTATGGTAAAAAGCAGTATTCGTAATCAAAAAATAGTACCCTTTGAAGACTTTTTAGACTTAGCAACTTTAGTAAAACTAAAAAAGGGGAGCTATCAAATCGGAGCTTACTTGTTGAGCAAAAAACAAGTAAGCGACACTAACAACACGCTGCAATTAGTATTCGGATATGAATGCACTGGCTTTCACCCACTGTTTAATTCATCAGAGAGACTAGAGGCGATCGCCAAGGCTTTTGAGAACGGCTGTAAAGAGTTTTCGGAGGGTGAGAAATTCACCTTTCGTTGGTCTTCGTTTTGCGACGAAGACAAAGTAATTGAAGACTATCGTCAAAGGCTAGCTAGCCCTGTATCTCTTGAGAGTGAGTTTCTTGATTGGGGGCAAGTTGCGCGGATGCAAGAACTGACGCGTAATCATCAGCGTAAGGATATCAAGCTCAGTATTTACACGACTTTTACTGTCCGCCCAGGAGGAACGGAAGGTGGTGACGCGGTAGATAGAGCAATAGTTAAGCTGGCGAACTTTTTACAGCGCAAATTCACGCCAACAGGCGCGACCGAACTCACTCTTCAAAACTTAATTCAAGTTCTTGAAAAAGCGATAATAGTCTCTTTGCGCCATCAACAAATACTGTCTGAAATGGGTTTATTTCCCTCGCCAAAATCAGACAAGCAATTGTGGGGCGACCTAGTTGATAGAATGGGTGCGAAGGCTGTAAAAGTGCCCCATACCTTGGTTTATGATACTGGTGAATTAAGGGAGGAGATTAACGAAGCCACGCCCAACCCATCGCGGTATAACGACCAATTACACGCGACATCGGTACTTCTGAATAACGGCATACCTCATGCTGATAGACGATGGGTATGTTTGCCCTACCAGAGTACTGACAAAAAGAAGTATATCGGCGTAATGACGCTTGCCCAAAAACCAGAGGTGTTTGCTTCAACCTATCAGCAAATACGCTTTTTATGGGATGTATTCTCACGCGAGGTTATTTATGATGTCGAGATAATAACGGAGATTAACCCAGCCGATCAAAAAATGATTAGGCTTACCCAACAATTGATTACGAGGCGGTCAATAAATGCCTCCGCTAGCGCCAGTAAAAAGACTATTGACGTAGGAGCGCAAATTAATACGGAGCGGTCAGTCGATGCTCAGAAGCAGCTTTACACGGGTGATGTCCCGGAAAATGTAGCTGTCATAATCCTTGTTTATCGTAACTCTCCAGAAGAAATCGACGACGCTTGCAGGCTGATTTCAGGGTATATCAATCAGCCTGCCGAGTTGATTAGAGAAATGCAATATACATGGTCAATCTGGCTTGACACTTTGCTGTTGAGACAGCGACCGCAGCTGACTTTTCCTTTCAACAGACGCGCCACTTTCTTTGCTAGTGAAGTAATTGGTTTAACGCCAGTCGTTCAAACAGCGCACGGTGATAAACAAGGCTTTGAATTAGTAGCTGATGAGGGTCAATCGTCAGTCTATATCGATTTGTCAAAGCCGAAAAACATGATGGTAATCGGCACTACCGGGAGTGGGAAATCGGTAATAATTGCCTCTATTATTTATCAATGCTTGGCGTTGGGAATGTCAGTATTAATGATTGACTTGCCCAATGATGATGGTTCAGGAACCTTTGGAGACTTCACGCCCTACTTTAATGGATTTTACTTTGATATCTCAAAGGAATCAAACAATCTTGTACAACCGCTAGACCTATCAAAGATTCCTGAGTCGCAGTGGGAGGAAAGGACAAAAGCCCATCGAAATGATATTAATTTAATCGTGCTTCAATTAGTTTTAGGAACGCAAAAGTTTGATGGCTTGCTATCACAAACTATAGAATCTGTAATCCCTTTGGGTACAAAAGCCTTTTACGAAGATGCTGACATCAAGGAGCGATTTGAATTAGCGCGAAAAGCAGGGATAAACACCCCAGAGTGGGCGAATACCCCGACATTGGCAGATATGGAGAAATTCTTCTCGCTTGCGTACATTTACTTAGGCTATCAGGACGACAATGTAGAAAAAGCGTTAAATTACATCCGCTTGCGGTTACAGTACTGGCAGGCTAGTAGCATTGGTAGCGCTATCTGCAAGCCTTCAACCTTCCAGGCTGATAGCCAGTTGATTACCTTTGCACTGACTAATCTGCAATCAGGAAAAGATGCAGAAGTGTTCGGGATGAGTGCATATATCGCCGCGTCCCGTCAATCCCTCTCCTCGCCCAACAGCGTGTTCTTTATGGATGAGGCTAGCGTATTGCTAGGATTTTCCGCATTGTCGCGGCTTGCGGGTCGTAAATGCGCTACGGCTCGAAAGCAAGGCTGTCGGGTGTTTCTGGCGGCGCAGGACGTTATCTCTATCGCCAAATCGGAGGCGGGAGAACAAATATTACAAAATATGCCATTGCGATTGATTGGGCGTATTGTTCCAGGCGCGGCTAATAGTTTTTCTGAGTTGCTGGGCATCCCTAGAGAAATTATCGATAAAAACGAAAGCTTTGTCCCGAACATTCAGCAATTATATACTTTGTGGCTGTTGGACTACAACAACAAATATGTGCGCTGTCGCTATTATCCCTCGTATCCCCTGCTGGCGTTGGTCGCTAATAGCAGAGAAGAACAAGCCACGCGAGATAAATTCAAGAAAATTCACAGTGACAAGTTCACCTGGGTGGCAGAATTTTCTAAATATTATGTCGAGTGTATCAAACAGGGAAAACCATTATGAAGGTTCTATCATCAGTCATTGAAAATAAGCTGTTGCTGGCAATACTAGCAGGTGTCGTGTCAATAGTCGGCTTTCAAGTATGGCAATACAACCAAGCTCAATACGAAAAGCTTATTAGCGAAGCGAAGAATGGCTGTGGCGTGTACATAGAATTGGGCGAGGATGCCATCAAGCGCTCCCCCAGCCTGAGAGCATTGAAATATCAAAATAAGCGATTGAGTGGATTAGAGCAACCGGGGATAAACTCTGAATCCGCCGACCCAGGTGCTTATATCATGCTTTTTCGATCCCCTGCTTCTACCCTTCCGCCTAATGCTTTGCCTTTCGATGATACCTTCTTCACCAGTTTATTAAATAAGGAAGAATCACCTAAAACATTAATGGTTCAAGCTGTTTCTTTTGATTTAGCAAAAAAGCAAGCGACCGTAAAATCTCTTTGTACCAAAAAACCTTTTGTAGTAGCCTTGGAGGACTTGTATCTTGAATACCAACCGATTGATCGTAATCTCAGGCGTAGTGATTTTGACATCCTTTTCTAGCCTCCCTGCCACCGCTCAAACTAATCAAAACCAATCTTTCTTAACTCAATTTCAACAAATTTATAGCAGCTTGCAGACTTACATTAGTAATTATCAGAAAGAATTTACTAAAAGTTTGGGCAAGTTAGAAGCTGAATTAACCCAGGCAATTGAATCTAGTGTTGGTGATTTGGGTATTCCTGATCCCCTAAAAGCTGGCAAGAATATCGAGAAAGTGATTCAGAAACAAGAAGGCGCGTTGCTGATATTAGACCCTCGCATTCAAGCCGGAAACGCTATTAAGGAATGGAACCAGCAATATACACGCGGTCAGTCAGAATCAGTACTAGGAGTTGAGGGTCAACGAGTGCAATCGCAAGAGGCAGCAATAACTAATGATGCCACTGCTCAATCAAGCGAAAATGCTGCCGCCGCCCAAGAGGATGTTATTACCCAAGACATTCTTAAAAAGGTCGCTATTCAAAACTTGCAAAATGTTGTGATTGCCAAGTCTATCCACTCAGAGGCACAAAAGCAATCCCGTTCCTTGGCTGTTGCAAATATTAACCTTGCCGATATTTCAAACAGGCTTGATGAGCAAGCTGCGGCGAAGGATCAGGAATCTAACGCCGCTACTCGCCAGATAATTCAATCTGCTGCCGCTAACGATTCATTCTGGAAGAATCAATAATCGAGTCACAATAACGTTACGATAACTCAAATGATAACGTTCTTAGTTATTCTTTTTGCCCAAACGACAGGGCAAAAAGCTGGAGAAGATACGGGCACTACGAATTCAGGCGAAATAGTCGAAGGCGCTATCTCAGGCGCAGACCTAATCTATAAATCGTTTGAGAATGATTGGCTAGAATTAGCATCTGGAACAAGCCCAATTTATACGGCTGTCGTCGCTGTTTCTACCCTCGCGGCTGTTGTGATGATTGGCTTTGCATCATTTGGCTGGTACAGGAAGTATGCAGAAGAAGGGTTTGGTTTTGATTTCATATCCGAGATGGTTTTGCCATTAGTAGTAATTGTAATGCTTAGTAATAATGGGTTCCTTCTCGCCAATACAACAGTCGCATTAAAAAACGTATCGACCGGACTAAACAGGAGCATTTTAAATATTACGAGAAATGGGGTAAACCTGAGAGATGCCATAAGGAATGTTAATGCTGACCAAAGCTTTGTCTTAGCCGCACAGATAGCCTTAGCTAAGTGCGAAAAGCTCAACAACGAAAAGAAGGAAGGTGAAGAATTGAGCGAGAAACAAGCTTGTATCAAACAGGCTGTGGAGAATACACGAAAAGACGCGCAGAAAGCTAGAGAAAAGACTGGCGCGGGTTCTGGAGTCGGAAGTTGGAACCCATTAGACCTTAGTGGCGAACTAATCAATAGCGCAATCCAAGGTTTTGTTTACGTAATTCTCAGTGGACTATCAGCAGCTTTTCAATACATTGTCCAACTGTCATTCTTAATGATTGCATTCGCTGCCCCAATCTTCCTAGTTGTATCTTTGCTGCCTTTCCAAAGCAAGCCTATTTATGCTTGGTTGGCTGGCTGGTTAGGGCTAACACTGGTTCTAATTTCCTACTCCATAACTGTAGGTATTATTGCCAGCGCGATAGTCTCTAAGCCTTCCAGCAATCCTTTGCTATTGCAACTTTTACAAGCCATCTTTTCGCCATTACTCGCGGTAGCCATAGGTACTGGTGGCGGAATGGCTGTATTTTCAGCTTTCACTAGTGGGGTTAAATTCTCGGTGGGGTTAAGGAGATGAAATTATTAGAGAGAAAAGAGCTAAACTTTACCCCAATTTTCTTAATAGTCAATGCTATTTTATTAACGCTCTTATTATTCATAGAAATTGTCAATTTTGCTCGGATAGCAACGTTTTCTAAAACGAAAGCTTCGACCTTGGTAGAATTGTCTGACGGCGAATCTATCAGAGTTATTCCTATAGGTAGCCTTGAGCGATCACCGCAAGCTATTACGTATTTTGTCGGGCAGACAATGACCGGACTTTTAAGTTGGAATGCTCTACCAAAGCCAAGCGATGATTACAAGATAGACCCCACCAAACAATTAAAATTAGATCCGGGGATATCGACATCAAAAGCCAAGATTACTACTAGTGCATGGGCTTCAGGTTTTGCGTTGTCAGAAGATTTTCGCGCACCATTCCTTGAAGAGATAAGTAATCTTACGCCGCCCGATGTCTTTAATGGGTCTACGCAATCAATCCTAAAAGTCAGCCTAATCAGTCAGCCGACTCGGATTAAGGATGGGCAATGGAAAGTAGATATGGTTGCAGAGATTGTTGTTTTCCAAGGCAGCAATTTAGTTGGTAAGCCCATGGCTTTTAACAAAACTGTATTTGTCAGGGCGATTGATACGGCTGCCCTGCCTAGATTTGCGTCCGATGTTCAAGAAACGGCCTCTCGTGTTCGCAAAGCGGGGTTGGAAATTTACAAAATCCAAGATTTAGATTTATGAAAAAGAACACCCAGTCAGCTTTGTCAGAGGCAACTATTGAGATAGAAGAGCAAGATTTTGCCGCCATGAACGGCGCTAAAACTTCTCACGCTAATGATTCAATTCAACCCTCCGAGAACCCCGCCCCAGAAGAAATTGTTACTGCTCGAACAGTCTCGCAATCTCCACTCTTAAAAATGGGCGTTGTTGCCCTGATTTGCCTTCTCTTCGTGACGATTGTTGGGGCAATGCTAGGCAATTCAATGAATGTGCTGAAATTTTCCAAGGGCATTGTGCAACCGCCCAAAGAAGAGCAAACGCCCCTAGCAGAGCCGGAAAATGAGACGGGCAAGGATAAAACAGCGCTTGCCCTGACTAGCCAAAATTACGAGTTAAAGCAGATTCGCGATCGCTTGCCTAGCCCAACGCCTACTCCTAGCGCAACCTTAGCCCCAGCCCCAATCGCACCCGTTACCCCTCCGATGCAACCAGTGCAGCGCCGACAACGTTCTTACCCAGTCGCCAGTCAGCCGACAGCGCCCTTCACTTTCCCCCAGGCTAGAGTATCGCAACCCCAGCCCCAGCCCAAAATTGCCCAGCCGAGCAGACAATCTCCTTTGGCGTTCCCAACGGCTGCAACCAACGTCCCCACCAAAGACCCCACTCAGCAATGGCTTATCGCTGCAAACGTTGGCAGTTTCAGGAGTTCAGGAGATGAATCAGAAAGCGAGAAACCCATCAAGACTAATGGAATTGAAGGAGGTACGGGAGGAGCTACACAAGTGGCCCAGAACACTACCATTAATTACAACGCAAAACGCGTAATTGTTGGCAGCACTGCAGAGGGGAGGCTAGAAACGCCGATCGCTTGGGGCACTGGTGACGCTGGCAACCAGAATTACTTGGTGAAACTAACAAAACCCTTAAAAGCCTCAGATGGTAGGGACGTACTACCCGTGGGCGCTTATCTGGTTGTTCAACTAGCAGAGTCCAATGGTTCGGGTTTCGCCAAACTGCGCGGTGTTTCAGTGTTGGTCAATATAAACGGCGATACGCAAGAAAAGCAACTGCCAGAAAATGCCGTTCTGATAATGGCCAAGGATGGTGGTTTCTTAAAAGCAGAGTCTCGCAGAGGCAGTAATCTGGGCAACAATTTCATCTCTGCTATTGTTGCGGGAGTCGCCAAAGCTGCCGAAGTACAGAATCGCCCCATAACTCAAGTCAGCAGTAACTCTAATGGCTTCTCTACTAGCTCCACTACCAACGATCAAAAAGACCTATCCGCCGCTTTTGGAGAGGGTGCATTTAATAGTGTTCTCGATAATATCAAAAGTTCAAATGTCGCCCGTTCTCAACAGTTAAGTGGTAGAGAAGAAGTATTTGTGATCGATGTTGGTAAGCCAGTGCAAATATTCGTTAATCAAACAATATCGCTCTAGTCACAATAACGTTACGGTAACTGAGGATATAAATGTTAAAGAAAACCACTATTATTGCAGCATTTTTAATCTTAACTAGCGCGGCAAAAGCAACGGCGATAACTGCCCGAACGGTTTACCAGAACGACGCAAACTCCAATGCCATCGAATTAAAGGTGTGGAAGGGCTACGGGCTAACTATTAATTTGATGTCTACAGGGGAAACTATCAAGCAAGTTTGGATCGGCGATCCAAGTCGCTTCGCCTTTACTTCAAATGGTGCTTTATGCCAGTCATCAGGCAACGATTCTGACTGCACAGGAGGTAAAGCGACTGTAATTTTCCTTCGCCAGATTGACCCGATCAACTTCCCTGTTACCTCTAGTAGCAATGGAAGCACTCAAATTACAGTACTTACCAATGATAATCTTTATCAATTTAAGATAGTCCCTGCTACTGGCAACCCAGCCTATACAAGCTTGGTGATTAAATCGGATTCGGAGCGTCCATTGCCAATTACGCGTCCGCGAACGCCGCAACCGCTAACAGTTGAAAAACCGCAATCAGCGCCGCCAGACTTCCCGCAGCCCTCGCCGCCACCACAAACAATAACAGTTCAAAAGCCTCAGCCTGTTGCTGTTTTACGCCCCAATCCTGGGACTACGCTAAATGGTGCGATTCAGAGAAACGATGCTAATGCTCTCGCTTTTGGGCTAGCAGAAGCTGGGCGCAAAGGTCAAGTTAAACCCGGATCTACCACATGGAACAAGGTGCAAGATGCTATCAAACTATTACGGCGTGGCAAGACAAGAGATGAGGCAATTTCGCTTTCTCAGGTCGATAAAACCATTTTTAATCAATTACTCCAATGGGGGCAGTTGTGAACAATTTTTCTAAATCTATTCGCCAAGAATTAGGGGATTTTCTGGATTTGTGTAGGTGTGAAGGTGAGTTATGGATGTTTCCACCAATCGGCTATTTGCTGCTTTTGACTACTCTTTTGGCTGTGGATAAGACTTAGCTTAGTCCTGCAACAACCTACTTAAAATGGCTGTTACCCATGCCCTTTGCAACCTTAACTGTATTGCAAATAAACCAGTACAGAAAATCCAAAAAGCTGTTAGCAGCAACAGGAAACGTAGTAGTCTGCCAACCCAAAAATGCTAAGTGAGGACTGGGGAAAGGGGAAAGGGAAAGGGGTAAGGGATTTGAAACCTTTCCCCCTTCCCCCTTCCCCTTTACCCCGCCAAGTTCACTTGGCGAACTAGTAGAGCTACAGCAAGACAAAAGTGGATGCGAGAGTTGTGCCTATTTTCATGGGCGACAATACGACCAAGAAATCCTAATATGCACGGTACATCCACGCGGCTCCAATCAAGAACAATGTCCCGATTACTTTAACAAAAATCATGAAACTTAAGCCTTTTCTACTGGCTGCAATAGCTTCTCTAGTTCCGCTTTCCGCCTCAGTCGCACAGACACCAACAATTAATTATTCGCAGGGCAAATACAAAACGGCTGCCCCCGACTGGTCAAAAATCACATGGGATACTTTGCCACCCGTTCAACAGCCAGGATTTTTAAAGATACCTAAAAACCTGATTTCGACTTTTGGCTACGACCCCTCGCGCTCGTGGACAGCAGGGCAAAAAGTAGACTCTGTTGTGATGTTGGGCGACGCGGATGATGCTTTTAAGATGTCGGACTTGAGCTTAAAGGCTATTGACACGGTGGCTTTGTCCACTACAGCCACAACCACCAAACCCACCCTCAAAGACTTTGGATTAATGCAATGGCAAACGCCAAAAACATTAGTTAAAGCAATGCCTGAATTAAGCAATTTGAGCCTATCAGAAGTTCCCCCATTAGCTGATCTATTTTCTAAGAATGGTGCTGGACTGGGTAGCAGCACTATTTCTCAAGCCATAGCCTCAAATCCTCAAGTCGCAAACCTGACACTAGATAAGATTGACCTAAGCAAATATTCGCTTGATTCAATTCCTGGGTTGGACAAAACTCAATTAGGAAAGTTTAAATCATGGCAGCAAGCTTATGTCAATCAAATTCCTAAATTAAGTCAAGTGCCCTTTGATAAAATGCCTCAGCCTATTAGCTCTGGCATTGGTGTTGTGGGTATCGCATCTGTTGTACTTGGTACGGCAGAAAAGGGCGACAGAAGGGCTGGGAATGATTACTTTGTTTCTGGCAGCGTTGTCAGAGGCGACCGCACTTTAACAGTCGCCTGTCCTCCAGGCATTGAATGCTCATACTTAGAGATAGGGGATTTTGCTGGCAGTCAGGGCGGCTTATATGGCAAGCGCTGGGCATCTGGCTCATCTCAGCAAGTTAAGGGCGGTTATGGGTTCCTAGCAGCCGTTAACGGTGGGAAGGAACCAACAGGGCGGCTAGTGTATGGTAGTGGGTTCAAAGTGGCGCTAACTGGAGTTAATGAATCCCTTGGGACTGCCGACTTTGGCTTATTCTTTAGGATCTGTGCGCGACCGCCATTTCAGCAGAAAACTTGCACCCCTTACTTCATTGGGCCAGTTCCCTGGTTGCCCGTGAGTGAGAATGATTTGGTTATCGTGGGGACGGGACGATGACAGGGACTCCTAAGACTATTGTTAAGCCAAATCAATTTATTCCCCCAGGACTTGAATCGGCGCTATTTTCCCCCGCAGGTTTAGGGGTACTCGCTTGTGGCGCGGTGATTGTAATCGCCAAAATCATCGATAGTAGGGGAGGTATTGCCAAGTTAGCGACCGCACGGTGGGGCGGCGCGGTGGAGAAAAAAGCCGCTCGTCAATTAGCGTGTAAGCAAATTCAGCTACGCTTGCACAATCGGGTATCTCTATATGTTGGCACTCCCAAGAATACAACGAGCGAGGTTATTAATGGAATCAGGAAAACGAGTATCCCTGAAGATTCAACAACCCTTTACTTCCCAGAAGCGCAACGGGGTATTTTAGTTTGTGGTGGGCCAGGGAGCGGAAAGTCATTTTCAATGATTAATCCGATGATTCGTTCGGCAATAGATCAGGGATTTCCCTTGGTACTTTATGATTTTAAGTATAGTGAGCAAGAATCAGCTACATCTACATCTAAGGGACAAGCCCCAATACTGGCAGGATATGCCGCTTTGCGAGGTTATGAAGTTACTGTATTAGCTCCAGGTTTTGCGGAATCTGCGGTTGCCAACCCCATAGACTTTCTTCGTAATAATGAAGACTCGGAAATGGCGCGACAGTTGGCGATTACACTCAACCGCAACTTTCAACTTGGAGAAAAGAATTCTGGAAATAACTTCTTTACCAATGCTGGAGATCAGTTGGTGCAAGCTGTTTTCATGCTGGCGAAAGGAACGGAGTACCCAGATATCATGATGTGCCAAGCAATCCTGGGGTTGCCAAAGTTAGTTAAGCGCATTGAGCAAGCAGAAAATCTGAATTTCATGGTTAGAGAGGCTTTCGCACAGTTTGTATCTGTTGCAGGGTCGCCAGAAACAGCAGCTAGTATTGTGGGTACAGCTAGCGGATTGTTCAGCCGCTTCATGGTTCCCTCGGCATTAGCAGCGTTCTGTGGAAAAACCAATATTCCTTTGGATTTGAAGGGGCGGCAGATGGTGGTATTCGGGATGAACAAAGAGAAGCGTGATGTAATCGCACCCTTGCTTGTCTCGATTCTGCATCTATTAGTTAGCCGGAATGTGGCTAACAAACGTACTTGTCCTTTGGTGTTGGGGATTGATGAATTACCCACATTATATTTACCAGCACTGGTTGATTGGCTGAATCAGAATCGGGAAGATGGATTGGTATCAATACTGGGATTACAAAATCTCTCAATGCTGATTGAATCCTATGGTGAAAACACAACTAATGCAATATTTGGTGGTTGTGCTACCAAAGCATTCTTTAACCCCCAAGATGATGTAGCTGCCGAACGCTTTAGTAAGTTTTTAGGTGAAGAGGAAATTAAATACAAGCAACGTTCTCGCTCATCAGGAGGCAAGGGTGGTGCAAGCATTTCTAATTCTGACCAAAACAGTACCCGAAAATTATTTGATGTCAATCAATTTAACACTTTACCATCGGGGAAAGCAGTAATTATTAGTCCAGGTTTCCGTTCTCGTGGTCAAATAAGTTTGCCAATCTTGCAATCAATTAAGATTCCTCAGCATGAAATCCAATCTGAAACTGACAGTGTGAAAGCTTGGTACGAGTTTCAAAAGTTTTTATCTAAAAAGTCTACTCTCTTAACTCCAGCAGATGAAGAAATGAGAATTCGTCGAGCAGAGGCATTAAAATTGTTGCCTTTGATAGAAAATCAAGAGCAATTATCAGAATATGCAAGTCTGATTTAAAGTGAAATTTCCTGCCCTTAATAGTCAACCCCTTCTCTGCGAGACGCTGTGCGAATGGGGAATTCAAAATTCAAAATTATTAATTCAAAATTAAAGACAAGACGCTCTCTACCAGACGCTGCGCGTAGCTTGCTTCTCCGTAGGAGTACGTGGACTCGCTTGCCGCCGGCGCTATCGGTCATCACAAATATTCAGGATAAATACCATGTCGTCACGCGATTTTTACTCACTTAATGATCATGACAGACGAGAAATTGCAAAACTTCCACCTCAGATAGCAGCCTTAGCAGATAAATATCCATGTGATACCAATTTAATATGAAGCTGCATATAATAGAGAAAACAAACTCGATAAATTAAAAGAACCATGAGCCGCCCTTTTGAGATTGAAATCGCAGAGAGCGAAGAAGAACTTAAAAAACGCCTACAAACAGCTAATTTAGGGAACCAGAAAGAAAAACTTATTATGCTGTGGTGGATAAAAAGCGGGCAGGCCAAGGAGCAGCAAGATATTGGAAAACGCTTGGCTAAAGATACATCAACGGTGACAAGATGGTTACAAAAATATAGATCGGGTGGGCTAGATGAATTATTGAAAATAAAAAAAGCTCCGGGAGCAAAACGGAAAATTCCTGAAGGAGCGATCACGGCACTTGAAGAGGAGTTAAAAACAGGAAAAGGCTTTAGTAGCTATGGTGCAATAGTAGAGTGGTTAAAGCAAGAGCAGGGGCTTGATATCGAGTATGCAACGGTTTATGCATTGGTTCGATATCGATTAGGGGCAAAACTAAAAGTACCACGTCCTCAAAGCCATAAGCAGGATGAAAAGTTAGTATCTGAGTTTAAAAAAAACTCGGTATCATTCTGAATTGTCTAGAAAAACATCTAGCACCCGGCAAGTGTGTTCGCTACCTGTGCCAGGATGAAACGAGGGTGGGACTGAAAACTCTTACAGGAAAAGTGATTACTGCCTCTGGAGTTAAGCCTACTGTTGAGGTGAAATGGCCACGGGAAAATTTTTGGATTTATGGTGCAATTGAACCATTGACTGGAGATCATTTTCTTTATGAATATCCAAAACTGAATGGCGAGTGTTTTCAACAGTTTTTGGACTGGCTATCTCAACAATTAGGTGGGGATTACGCTATTTTACAGGTTGACCAAGCACCTGCTCATACAAGTTCAGCAATTCGTTGGCCAGAAAATATTATTCCTCTGTTTCAACCACCTTCAGCCCCTGAACTCAATCCCATTGAAAGGCTTTGGCAGCTCCTCAAGAAACCACTCAAAAATCAGCTTTTCTCTTCTTTACAGAATTTACGCGATCGCATCCAAGAAATATTTAATCAACTTACACTTGAGCAGGTAATATCTATCTCTTCTTATAACTTTATTCTCGAAGCTCTTTTCTATGCAGCTTCATATTAAATTGGTATTAGCTAAAAACTTTAACAAGCCTGTACGACAAAGCTCAGTAGCAACCCAAAAGGCTTTCTTAGCTAAAAATTTTAAGAAGCAATTACTACCAATCCCAGCGCGAACACCAAGGGTTAGATTACCTAAAAAGCTTAAAAAACACTTGAATAATATTGAGTACGCTAGTCAAGTATTACTTGAGCTTCGTAGCAGAACTCAATTAGCCAAATTGCCAGTAGTAATCGCCACACTGCGTAGGATATCACCCTACGTTTTTGAGGAATTGGTACTCACTTGCTGCTTTGAACAGGGGTGGCAAATTCAACGCAACTTTCGGTACACCGGTGACGGCGGGATAGATGGTCGCGTGTTGATTTTGGGAAAGCTTTATGTAATCCAGGTTAAGCGTTATGCTGATTACATTAGCCCAAAACACATCAAAGATTTCGTATGCTGTATTGAAGGAGAAGGAGCTAATGGTGGATTCTTCGTGCATACTGGCATAACTGGACAGTTATCAAAACAATTGATTCGTCGCTCCGACAAAATAATCTTAGTGAGCGGTCAGAAACTAGTAAATTTTGTCTTAGGTAAGCAGTTTAAAATAGTGGGAATAACAATACCAGTAAAAACAGTGAACAGTTATCAGTAAACAACTAACTTATGAATGAATGAATGAATGAATGAATGAATGAATGGAAATATCTGATACCTGATAATTGATAACTGATAAGTTAGCGTCGAAACTGTAGATGCTCCCCGTTATCATCTGATTGTTGAGGGTTTATTTTCAATCTCTTCAGAATCGATGGTTTGTCATCTCTAATCAGTTGCCTAACGATGTTCATTTTCTCCTCAAAAGTCAAAGCTAAAGCATCAGTTGTAACACTCGTAAATAACTCGCTGACCTTTGCTCCTGTTACCTTTTCACCTTTGACATATTTTCCTACTTCCATAACTACTTCTGCCAATCTTTCAATATCTAAACCCTGAATCATCTGTTTGAGATGCAACTTTAATTCTGCTAGTAATGTTTTAGCTAAGGTTGACTCAGTAGCTGATTGCTCAACAGAGTTAGAGGTGGATAAAATAGCTCTCTTCTCTACATGAGATTGCAACTCAGCCGTCAATGCTATTTCAAACTCATTGAATGTACTTTTAGCAGCAACAAGTTGTTGATGAGATTGAGAAAGTTGCTCTGTCAATCCTAATACTGCTTGGTTTAAAGCAGACTCGATAGCTGATTGCTCAACATAATCAGAGATTGACAGAATAGCTTTATTTTCTGCATAAGATTGCAACTCAGCCGTCAATGCTGTTTCAAACTCATTGAATGTACTTTTAGCAATGACAAGTTGTTGATGAGATTGAGAAAGTTGTTCTGTCAATCCTAATACTGCTTGGTTTAAAGCAGACTCGATAGCTGATTGCTCAACATAATCAGAGATTGACAGAATGGCTTTGTTTTGTGCATGAGATTGCAACTCAGCCGTCAATGCTGTTTCAAAGTCATTGAATGTACTTTTAGCAGCAACAAGTTGTTGATGAGATTGAGAAAGTTGTTCTGTCAATCCTAATACTGCTTGGTTTAAAGCAGACTCGATAGCTGATTGCTCAACATAATCAGAGATTGACAGAATGGCTTTGTTTTGTGCATAAGATTGCAACTCAGCCGTCAATGCTGTTTCAAAGTCATTGAATGTACTTTTAGCAGCAACAAGTTGTTGATGAGATTGAGAAAGTTGTTCTGTCAATCCTAATACTGCTTGGTTTAAAGCAGACTCGATAGCTGATTGCTCAACATAATCAGAGATTGACAGAATGGCTTTGTTTTGTGCATGAGATTGCAACTCAGCCGTCAATGCTGTTTCAAAGTCATTGAATGTACTTTTAGCAGCAACAAGTTGTTGATGAGATTGAGAAAGTTGTTCTGTCAATCCTAATACTGCTTGGTTTAAAGCAGACTCGATAGCTGATTGCTCAACATAATCAGAGATTGACAGAATGGCTTTGTTTTGTGCATGAGATTGCAACTCAGCCGTCAATGCTGTTTCAAACTCATTGAATGTACTTTTAGCAGCAACAAGTTGTTGATGAGATTGAGAAAGTTGTTCTGTCAATCCTAATACTGCTTGGGTTAAAGCAGACTCGACAGATGATTGCTCAATATAATCAGAGATTGTATTTAAGAGTTGTCTGGTGGCTGGTTGTGAAGAATGGACATAATTTGCTTCTCTATTAAAAATTGTTGAATCTTGTCCGTTAATTTGTCTTGAGAGTTTCTCTGTTCGTTGACCTCGAAGCCCATCATCTGTAGAGCTTTGGTTAATTCCTGCAATATCGTCTCCATGTCCGAAGACTTTTTCGAGTTCAGCATCTCGGTTAATTGCTGCAAGAAGTTCGACTGATTCGCGCTCATTTCGATTAGGTTCTCGGCTTGGCTCGTTTCTAAGAACTCGATTTTCTGGGTTAATTGCTGGCTGTTGGTTTGTAACTGCTCGATTTTCTGGGTTAATTGCTCTATCTTCTCGGTTAGGAACTGTATCTGAGTTAGGTTGTTGTCGTTGGTTAAAGTCATGGGTTTGTACCTGTGGTTTATTTTGTAAAAGATAGGGAACAGGCAATGGGGAATAGGCAACAGTTTTTTCTATTTCCTCTTCCCTGTGTGTTGGTAAGAGATCCAATTTGTCATTCCCTGTTGCCCGTTCCCTGTTGCCTGTTCCCTCAAGTTGTATAGAACGTTGTTCTGGTATCGGCTTACGCAAAGGTGGAAAAGCCGCAGTCTTTGAATGCTGATTCTGCTGTTGCCAGTCCCGAAAGGTTGGAGCAAGATGACTCAATTTCTCGTAAGCGAGTGGCCCACTTGCGACTATGAAATCATCAACACCTTTAGAAGGCCCTGGCAAGCTGACAACTTTTACTCTTGCTCCAGCTTCTTGTAACAATCTTCCAGTCACGGAAATATCTCGCTCGATATGGAGCTTAGTTTCAGGCTTGGTTTCGTAGTCAAAACAGAACTTGAAAACTCTCCCTTGTGTGGCGAAAACCGCTAATTCCTCATGTACGTAAGACTTGCCAATTTTCTTGCCAAACTCATCTTTGGGAGTTCGGTATCCCGCCGAAATCCCAGGTAGCCCAATGGCAGCATGACCCTGACTCAACAGACTGGCTGCTTTTTTCGCACCTTCTGCGATCGCACAGGGGATATTATGTTTCCAGACACAGTACCAAAATCCTGACTGGCGATCGCTATCACTGGGGTTCACCTTGTGTTTGGAGTAAATGCGTTCGGCAATATCGTCAGGGACATCTAGCAAGAAGATACTTAATTCAACTTTTGGGGGATGCTCATATTTAATGAATTTCCCTTCAATTATTTGCCCAGACTCATCTTTTTTGGGTCTTGGTTGATTTGGCTTGTAGCATCCCCATCGTTTAATCGGCGGTTTCTCACCTGGCTTTAAGTTAGCAAATGTTCGCGCATCAACTCCAGCATCACACCACCATCCACCAGCATCAAGATGCGAATATGCCCTTATAAAACCATCTGTTAGCCGTCCTGTATTTGTTCGATTCAGTTTTTCGCTGACCATGAGCCGTTCCCAGGCTTCATGCTCACCACCTGCATAGTTAAACTGAAGACTCTCAAAGTTCAACGCTGTAATATCGGGATGAATAGCACTATTTTCAAACTCCTGCCAATCCTTTGGTTCAAGAAAATTGGGAATGTCTTCAGTATGATATGGTGTCCAAAACGCTTCTGTGGGGACAGGAGATTTCAGTACTGGCTTAGAGAAAACCGATTCAACAGTATTATAATTTGGTGTCTCTTTCAAGACGGGCAAGACTTTCGGTACTTTTATTGATGAATCATGGCTTGTTGTCCGGCTAGATGCAACTGATTTCACAATTGGCTCGACAAAAGGAGTAGATACTGTCGTCTCTTGTTTTAGTACTGGCTTCTCAAAAGGGGCACTTATATTTATAGTTATTGCTTGGTGCTGCTTGAAAGTCGATTTCTGAATTTGTTTTCGTAACAATTCCAAGGCATTTTCTTTAGACTTCGACTGTTGCGCTAACCAGAGCAACCGCGTTGGATCTTCGGTGTAAATCTTTAATTCATGCCTTGCACGGCTGGCAGCAACATAAAAACTTTCCTGTCCAATAGTGAAATCTGCCGAAATTAACACCCGATCCGCAGTTTTTCCTTGGCTACTATATGTTGTACTCACAAGGGCATAGTCTAAGTTTTGCGCCTGTGCCAAACTAATGGATTCAGTACGCTCATCAGCATATTTAATCTGGACTATGTTCAGGTCGATCCCTGTTACAGTAAACTCCTGTCCGTTACGTCGTCCCAATTGCCGATCGTTTTTCTTCCATTGCAGGCGATCGCCCACAGCAATTTCAATCTGGTGACTCTGATAAACTGCTTTCTCAAAAGCCGTGTCTACCTGCAAAATCTGACGTTCATCACTTATAAGGGTCAACTTATCAGTAGTTCGACCTACCACTTCATATAATTTGCCTTTAGAAAGCCCCCGGCGTTTGTAATCCCGTGTGGGAATGATCACATCACCAATTTCAAAGTTATGGGCAAACCGCATCTGTACTTTTGTCAGATTTTTGGTTTGCAATTGGGTGATGGTTGCAGTTTCTCCCAAAGTTCCTTCACCCTTGAGCTTCGAGCGAATCGCTTGGGTAAGGGCAAGTCTTTCTGTATTTGTTCCAGCTAACACAAGAGTTTTGAGTCGCTGCTCTGGTGTCCCTACTATATAATCATTGGCGATCTGCTCTATTTTGGATTCTGAAGAAACAGTTTTTATTGAGCCGGTCGCCAGTAGATGTTCAAATCCCGCTTCTACTCTGCCATCGGCAATTAAATCTACTGCCAGCTTCAGTTGAGGGTCTTTTTGGCGCAACGATTCATTGAGGTGTGCGGTTTTGATTCCCGCCTGTTGCAAGGATTTGAAGGGATTCCCTGCTGATACTGCTGACAACTGCCGAGTGTCACCGACTAAAATCACCCTAGCTTGAAGTAAGGTTGCTCGTTGTAGGAGTGCATGGGCATCCTTAGCACTGAGTAAACCCGCTTCGTCCACAATCCAGATTTGATTTGGTTCAATTTCTTGTGGTTCAGTGACAAGTAATCTAGCCACTGTCTCAGACTGAATTTCTAACTCTTCACTCAAAACCTTAGCAGCAGAGGAACTAGGGGCAAAGCCAATAATAGTGTATCCGGCATCTGTGGCTATCGCTTTCAACTCCTTGAGGGCGAAAGTCTTACCAGCACCAGCTACTCCCTGCCATGCAATGAACTGGTCAGATGTTGTTGCAGCTAATTCTACTGCTTGGCGCTGTCCGGTATTTAGTAAGGTTTTCTGTAACTGGCTCTCAACTACTTCTCTATTAGTTATTGGGACTACTTTTCCAACACCTTGCTGCATCAACTCAATCGTCGCCAACTCCCGCCTCACTGCTGTCATCGTCGTAAATTGGTGAGTCAACCCTGGCAAACCGATTAACTCCTGATGTTCTCTAATCAGGGGTGCAATCGCTGTTACATCCGTAGCTAAACGTGATTCTAGGATGAATTTTTCTAAATCCTCTTGTCTAAAAGCGACATTTCTCTCACTGCAATGTGCGATCGCATCATCTAACGCATCAATCAGACTTTTTTGCTCAACCACAAGAGGAGCCTGTCCTTTTCTTGGTTCTCCTGGCTTGACAAACGTGATACCTAACGCCGCAGCTTCTTCTTTCCACAATGCAACTAATTCTGATTCTGGTAGTTTCTGCTTGCGCTGGCGGGTATCATCCCAAATTTTTTCACGTTCGGCCCAAGTCGAATTAGCACCAGATGAGGCGATGATTTGCTGTCGCCGCTTAGAAAAAGCCTCTAAATCCTCGAATTTAAAGCCTTTTATATCAAACTGCCCATGTAAACGAAGCTCTATCTCGTAGCCAAGCTTCTGCACCTCACGCGCCAGAGAGCTTTGGTATGCCATCCCCAAGAATTTTTTATTGGCGAATATTTCATTATTACCCAAACTCAACCACCTACCATCTGGAGTTTGGGTCATGTTCATCAGCAAACAATGGGTGTGCAGATGTGGGTCTAAATCCCGACTTTCGATGTGATCGAACTGCGCGGCGACCAAGTTACCAGTCTTAACTCTATGTCTGCCGCTATTATCTGTCACTCTGGTATAGGCATAACGCTGCTCTATTAGCTCCAGAGTTTCTTTTAGCGCCTGATGGTGAGCATCAATCAAACGAGTATCCCCGCCCACCAAGGCCATCAAGCTTACACTTTTGGGCGCAGAAAATGTACAGTCTAATGCGGCTCTGCGTTCTCCTTTCCCCTTTTCTTTGACTACTCTGGCATTCAATACCTCACGACCATCAGGCGTAAGCCCCTCAATGATATTTTTAAAAGCTTCTTCATCATCGACTGCCCCTGACAACCCCAATTTTTCAGCACCTTGACCACTCCAAAGCGACTTACCTTGGTGATAGTAATTCTTGATGAAGTAGTTCACCGCCATCTCACTTGAGACGTTAGCCGCTGTTAGCATGGCTCACCTCGAAAAATGGGGTTACAAAAGTTAATCTTTGTTCTATTCCATCTGTTGGTGCAACAAACTCTCGTCAAGAAATTCTGATTATTTTCTCTTATTGCAAGATAATCACCCTTGCAATAAGTATTGAAGTCAAAATCAATCCCCGTCATTAAACTTCGTAGTGCTTGATGACGAATGAAAATTTTTTCGTGAGACTTTGACCAAAACAAAATTTTATTTCCCAAACTCTCCTGTCATTTAATATAGCAAAAAATCGAGCATTCTTTCCACCAAATATGGCGTACTGTGCGTCAGAAAAGGATGGATTCTAGGGCTTGTGGTTATTTCAGCTAATTACTAGATAATTGGGAGAATCCTTTGGAAAATTGGGAAGTATCAGGAAGTACTAGGAAGTCTTGGGAAGTCTTAGGAATTGTTGGAAAATATTAAGCTAATGAGAATTTTGTGACTAGATGATGTTGAATAGTTGAAAAGGTAAGAAATGAATTAGAGATTTGGGAGATATTGTTTAGATATTGGGAGATGTTGAATGTAATTGGTGATTATTGGAAATCGAGGGATTTTGTGGAGATTTTCTATCAGATGCACGAATTCATGGAAAGTCAAAGAGTATTGCCAAAACTGTAATCTTTCTTCGTAAATGTGGAAAAAATCACGGTTTGGGCGGTTCACTTTGAGAGTAATTATCAATTAGATAGACAAAAAAAGGGTCAAAAACAGGGAGAAATTTTCTTGTGGATTTAATGTTGAGTCTTGATCCGGGAACTTCAATGACGAAGATGGTTTATCGTGTTCTCTCGGAGATTCCGTACAAGTCAGAATTGCTGTGTATGGAACCAGAGTTAATTAAGATTTCCAAAGATTCGTTGGATTTATATGAGTCTGGGCAAATGAATCGGCCCAATCCAGAGAATGAAGCGTGGATAGAGTACAACGGAGAGTATTATGCGGTTGGGTTTTTGGCCCAAAAGTATTTTGAAGCGCGAATCAATTTTTTAGAACTCAAGTATGAGAACGCGATTCCAAAAACTTTGGCAGCAGTGGGGGCAATAGCGATTAGAGATTCTTTGAAGGCAAACTTTGATTTATCATTGGGACTGCTATTGCCTTATGGGGAGTGGGAAGATAGAGAGAGATTAGAGAGGGGTTTAACTAAGGCACTGTCTAGTTTTAGCTTTCGAGGGAAACAATTTTGTATAAATCTGATTAACTTTCAGTGCTTGCCCGAAGGTGGGGGACTGATATTGACGCGAAGTAAAAAACTTGGCACAGATTTCAATAAAATGAATAAGCTGTTACGCAGCTTGATTGTATAATAAAGCTAAGTAATTAACCTAGCATTAGCCACCTATGCCAGCAAAAAACCATCTTTCTAAAGAGCAAAAGGAACGGTTACTAAAAACTCTAAAAGAGCATGAAAATCCATACGTAAGAGAAAAAATATTGATTTTATTATTAATGAATGATGGAAAAACTTATCAGGAAATTAGTAAGTTTTTAGACATTGCATATCCAACGGTAGCATATTGGGCAGTTCACGGCGATCCAGATAACCTAGAAAGTTTTTTAGATGGAAGAAGAGAAGGTAACTTCCGCAAAGTTACTAAAGAATATGAGGATTTATTATTAGAAACAATTGAAAAAGAACCACTAGATTATGGGTATGATTTTGGTCGTTGGACGGCAGCAAGACTAGCCACGTACCTCGAAAAGATAACAGGAATTAAGTTAAGTGGTTCGCAAGTTGGGAGAATATTAGAGCGAAAAAAGTACGTTTACCTTTGGGCAAAATACAGCCTAGAGGACAAACAGAATCCTGAAATACGTAAGGCATTTAAAGAAAAATTGTCAGAATACTTAAGAATAACAAATGTTGCCCCAGAGCGTTTACAGGTATGGTTTTGGGATGAGAGTGGATTTAGTTTGAGAGTGATAAGAAGAAAAAATTGGGGTAAGAAAGGTACAAGAAAACAAATCACAGGTCAAAGAAGAAGAGGAAGAGTAAATATTATGGGAGGGTTACGCTATCACGACAAGAAGAGAATGAATTTTGTGATTAAAAAAGGAAATGCAGATGTATTTTATGAGCAGCTTAAATCTTTGAATAATTTTCTTTTGCAAGAATGGATAGAGCAAGGAAATCCAATTGAGACTTTCAATAAATGTTCGGCGAAAATAGTGATTATCTTAGATAATGCCAGCTTCCATAAAAGAAAAGATATTTTAGTTCGTATCAAGGCAGAAATGCCAAATATTATCCTGGAATTTCTACCACCTTATAGTCCAGATTATAATTTAATTGAATTGGTTTGGCATTCAGCAAAAGAATATATAGCTCATAGATTGTTCGAGTCAGTATCACAGCTAGAAGAGTTGTTAAATAAATTGTTAAATGAAGGAGGTCTTATTATTAAATGGGAACGCAAAATTAAAAATAAAGGTAATGCTATTTATTAAATTTAGCTGCGTAACAGCTTATTGCTGTGGTGATGCTGGGTTTTCGGGATATATCAGCCGTAATCTTTGAGCGGGGTATCTCAACTGGAAAAACGGAAGGATTGGGCTTGGCGTGGATGCTGGAGAGAATCAAAAGCCGAACATCAGGGCAAAACTTACATGATCTGTTAAAGGCTGTTCATCTATCAGGCCCGACATTGAAACCGAGATACTGCAAACCTTTGGCTCGGAGCAAGAAGTCTGATTTTAAGGTTGAGGAAATAGCACAAATTATTGAAGTGGCTGACTTATCTCGTAAAGAATACTGGGAAAAGGTATCCACTTGGCTCAAAATTAATATTCCTGCCCATATTGAGCAAGTCATTATTGGTGGTGGAACGTCGGAATATTTAGGCTCGGAGTTGAAAAATTTGTTTACTCATACCGACATTTCATGGGCAGCAGAATTATCTGAGGATGTGCGTTTAGCTTTTAACCTGCCGATTAAAAAAGATGCCTTGTGCTTGCGTTTCACTGATGTATATGGATTGTTTCGTTACCAACACGCTACATCATCCATTTCAACTCATCGTGCTTCTTAATTAAAGGAATAATGAAATGTTTTCAGATGTTGAGTTTCGCTTACGAAGTAGAGTTAAGGCTGATAGCTCCGAAGCGGTGGTAATTAAGTATCTAAATTCCAAGAATACTCTTTATCCTGCTAGGGATATGGCGATGATTGCCATTAGCAGTTATTGGTTGCCTTTAGCTTATCAAGCTATGGATCAATCTGTGGATTTAGAGCAACACATTCGTGCTTGTCTTTACCGCCTTCAACTCCACTCTTCATATCTGATGGGACTGCTGGGAGAGATCCCCTCTCAAGGAACGCCGATGATTGCAGTAGCCTCTAATCAATCACAGCCACTACAACTAATACAATCAGAACCATTAGCAATATCCAGGACTTTAGTCAAAGAAGCATTACAAATAGCCAGAACTCCCGTACCAGAAGAATTGGAGTCGGAAACTGACTGGTTAAATCCTTTTTAGGACTGACCGAACAATTCGCAATGACGCTCGTTTGCGGAGCGTGATTGCGTACAGGCCTTTGGGCATGAAAACAGCGGAGCCGGGCGTAGCAAGAGTGCGAATTGTTTTAAATAGGAGTGCATGATTATGTATCAACCACAAGAACTTTTTAACGAGCTTTCAACATCAGAAATTAGCCGGACTTTACGCTTGAGTGGCATATCTGAAAAAGAGTTATATACAGAGGATGATGCAGACCGTTTTCGTGAATGTCGCACCTTAATTGAGCAGGGTGGAACTGACGAGGACGTGATGGCCCTATTATCACCAGTCGTTGACGTTGTGCTGTCAGAAACTCCGGATAATTCTTTAGCTGAAATCAAGAATGGGCGGAAAAAGTCTGGGAAAAAAGCAACTAAATCCTTAGATATAACTGAATTACTAAGTCTTGCTCGTGAACAAGGCTTTAAGCTTACCCTGACTACAGCTTTAAAGATTTTCGCTGATTGCGGACTAAAAGAACAAGATGAATATACTTCAGAGGAATCCGAGCGTTTTCTCGCTGCCTGTAACTTACGACATCAGGGAAAAACAGAAATTGAGATCGCAGCAAACTTTGGAGCAGGTGTTTTGGATGCAGCAGATATCGAACTAAGCCTTGAAGAAACTGAACGACTCATACAAGATTCTGGCGATTTACTTTTTGGGGAAATGCTGCGAGAGAAAGCTGGACAACACGCTGCCATTGCTCCAGGTTTGTACTTGAAATATTTAGCACAAGAACTAGCTTCAGAAAGTTCTCAACAGAATTGGCGTTCCTTACTTGAAATGATTAAAGCTCGTGCGGTGGGAAAGCCTCAACCCCAATTTACTTTGAAGGTGCAAACCCTACAGCTACAGCAGCCCTTGAACAGTTTGCCGCCGAACTCAGAGAATGGTTCGACTTCCGACTAGAACAGGAACGACAAACTATTGAGATTCAGGCACTAAAAGCCTCTGATGCCAAAGCCACCCGATTAGCTGCCCACAAACTCGAAAACCTGCAAGCTTGGAACGAAGCTCAGGAGTCACGAAAAAAACTCCGCAAACAACGCTCTGAAAAATTCAAATCTAACCTATTTTGGTTTGGTCAGTGGATTGGTTCGGGTCGCTCTGGGATTTTCTTTTTCATCTGTGGCGTTTTGATTTCTACAACTGCTACAGCCGTGGCAATCATTAATCTACCAACTTTCTTGTCTTGTCCTAATAGCAAAAGTCTCTGTTATCAGGTATATCAAATGCGATTCAACAATAAAAGTGTGATTCTTCCGGGACAAGCAAAGGATATCGTTGCAGAGTATGAACGTAACAAGACCAAATCTAAACGACGCAAGTAATTAAGTTTTTGGGAAAGAGAAACTGTCTGTTTTGGTTTTCCCTATCTTTGGAACAGCATCAACAGTTTGATAGAGGGATGAAGTTATGAACGACCTAAAAGAAATTAAACTTTGGGACGATTGGGATGATATCAATTTATCAACTCCAGAACGTCGCATTGAACGCTTAGAAATTCTGCTGTGCCAAAAAGTCCACAAAGGCGAGGACATATCTGAATGTCTGCAAGTTTTAGAGTACTTGAAAAATCGCACGACTCAGCAAAAGTTAGAGTCTGTTTTCTTTAGGCGAGTTCAGTCTCAACGTTTATGAATATTTACTTTCATGCCAAGGTGAGGCGATCGCTTTTTTTCACATATTCAGGTCAAATCACTGCATTTGATGGATAAAAACTTTCTTTACAGGGTAACTCACCTACTTTAATAAGAGGTGTCCTTGTCGAAAGGCAAACTGTCAACATCCTCAAAGTTATGCAGGTCTTGCTCCATCTGCTGCCGACGTTGGACGTAAGTTCTGCTGTTTCCAATCCTCCCTTGCATCAACCATTCACCAAAGTTGATGCCTTGTTCTACGTGATTGGCAGACATTTCATTATAATCATCAACCTCTATTTTCTTACGCCACTCAAGCTGTTCGAGGGCACTTTCACTGATGCCAATCTGACGAGCATATTCTACATATTCAGGTCTGAGAGAACCATCTGGGTTGAATTCTTTTTTTTCTTGTTCAGTGAAGAAATCGTATGCTGTGTAGATTGGCCACGGCTCTGGATCAGTTTCGTCCAAGTGCTTCCACTCGTCGTATCTTGCTTTTAGTCTAGAGGCATAATCATCAATTGCCTCGTTACTCATTCCTACAGATAACATTTCTTGTCGAGCTTCATTTTTCAAGCTGCCATCTGGATGGAACTCTTTCTTGTGCATATTTATCCAACGCTTAATCCTTGACATAAAAACCTCTCAAAAAATTAATTAATGTTCATCAAACTTTAAATATTATGACTTTGGAATTGAAGCATTTTGACCCTCGTTTAAATCAGTGGATCTATACAGACGATAACAAAACGAACTCTCAATCAATTCTAACTGAAAAGCTCAATAATACTTTACTGGAATTCTACTTTCCTGATAAAGAATTTTCATTTGGACACTCAGATGAATACAGCACTGCTGAAGAATTAAAGAATCATCCAAATGGACAGATTTTATTGCTATCTTCTAAGACTCGCTTACTTTATGGAGATAAAGAATGCTTAGAAGTTATCCAAAAAATTTGTCCCGATAGTAAAGACCGTGGGGCTTATGGTTCCATCTTTCTTGGGGCTTGTAAAAATGCGATTCACGAAAAGCTAAACATTCTGGTAGTAGATGATTCTACTGAAAAGGCTGGTGAAAATGGAGGGATATTATCAAATGATTTAGCATATAAATTAGTTGGGGACTGTTATGGGCAGATTTCAACACAACTCTATGACAAAGTAACCTTAAGAGAATCTCAACCAGATAAAAGCTATCGTGTAATTCAGCATCGATTTGGTTGGGTGGATGGAGTTGGAGAAGATACTACTAAATATCGTTTTGGCAAAGGAACACTCCGACCATACAGATTAGACGAAATCAAATATGCAGATCCAAATAACAAACCAAAAATAGACATAATTCTCCCCGTAAGCAGTTTTAAGGGAACAGACAAGGATAGACCCAAAGGCCCCACAAAACCTCAAATTCAACCAGGATTATATCAGCAAAATATTTGGTTAGCTGAAAAAGGGCAATCTCAGCAAGGTCAGATGTCTATCTCCCAACTGCTGGCATCTTTCCCCCAAGGAATTAAAGATTTTGCCGAGGAACTAGAGGTGCAAGCTCAAAGATTAGCCTCTATTCAAGATAACCCTAGAAATGTTGCTGCTTACTATTGTGAAAGATATGAAAAACGTAAAGAATCATTGAGTCAAAATAAATTAAAAACATCAGATATTATCAATCAAGAAACAGATGTTAAAAACTTAGGGACAAATGATGACTTAGATGCAGATCATGAGTTGGATGACGAAAGTGCTAAAGATGACTTGTTCATGTACAAACTCATTAAAGCCGATTTACTAGGGCATCAGCAGCTTTTAGAAACTGAGAAGGTTAAACAGGAATTAAGTCGGTTTGTACAAAGTGAGTGGCGAGATATTGCTGTTGGGAAAACGCTTACTTTTGACCGAGGAATGATTATTCCCTCTAAGGAACTCAAAAATGGTGAAATCTGTGTCCCTTGGCTGAAGCTTGGAGAAAAAGTTCTTAACTTTCGCTCTCCTTTCCTCAACTCTAATGGATTGTGTGTCTCTACTAATAAACATGTTGAAGACAGTGTTGCGCCAGATGGTAAATCTTTGCAAGGAATAATTGTAGTCAACGATGAAGACCACAAACGTATACTTGCGAGGATTGAGGCGCTAGAAACTCAAGGCATTGAACACAACGAAGTTAATCCCCTCGAAACCGAATCAGAACGCCAAGCACGAGACTACGATGGTGATTGCATTGGTGTGGCAAAAGCCAGCTTATACCCCAATTTAACAGCAGAGGCAGAGCGAAGAAATCTTCCCCAAAACGCCTATTCGCCCACGGTTAAGCTCAAAAAGCAATCATTTTATTTGGAAGATGGAAGCCAGCCCCCATTTGAAAAAATCGCTATTCACATGAGCGATAGCATCAGCGTGGGCATAATCAACAATCAAGTGACAGCACTGGAGGCATTAGAATCAGAAATTGAGGTACTAAAGACTTACGGTACTTTTGAGCAGAAATCAAATTATCTAGACCAAGTTTCTAACCATTACGAAACCCTGTTTGAGCAAGAACGCCAGAAAGATCCAAAGTTAATTCGAGAAGAATACAAGCCTTATATGCAAGGGGTTGTTGAAATTGCTCATTGTCAAAGAACTCCCGAAATTATCCAGCAAGCAATGGACATTAACCGTCAAATGTACCGGAGCATGATTGAAGAAGGATGTTATCAAAACCAAATAGCGGTTGATTTATTCAAAAGTGCTAAAAAACCTGAGATGAATTTAATCCGGGAAAACAACCGCTACTTGTATCGTGATGTTAATTATATTAAAGATAAGAAATCTTCGTCAGTTTATTTAAGTACGGGGATAACACCAAAGGGCTACTCACCAGTAGAATTATTAATTAATCAAACTAATAAATATTTCCAAGAATCACAGTTAGAATCGCGCCCCATCGTTCAGTTTAAAGACTTGTTCAAAGGGGTAGAATTTACACCACAGCAAAAATTTGCAGCGATCGCCGCCAAGTACGAGTTTGATCAGAAATTCAACGCTGCGGTTCGTGCCTCAAGGCGGCGAGAAACAGAGTCTGGCCCTAGTGCAATTGTTCAAACGGATTCAGGAACGCAACTCGAAATTACCAACCTCACCCGCTACGGGCATCCTCTAATCTGGAAAGCCCAGACACTTAGTATTCACCTAGATGAGATTAAATTCACAAATAGTGAACGCCCCCATAAATTATTAGCGGTTGCACAGATAGATGGTGAGATTGGGGAGGATGGAAAACCCGCATACCGCAACCTGGGGACAGTTAGCCAACAATCGCAAGCAGATTACAATCTCAAGGCGGGAATGACCATACAGGGAGCTAAACTCTTAGAACTAAAACCAGAACTTACTAGAAGCCAAACTAAACTACTCTTTGCCTTGGCGCAGGAGACGGCAGAAGCATTTTATGCGAAAATCCCAGAGTCAGAAAAACTTACAGGAGCCGCCGCCGCTTGGAACATCTGTGCATCCCGCCAGGATGAACTCGAAGTTGCAAGAAAAGAAAACGCAAACCCCCAAGCGATCGCTAAAAAAGTTTCTAATTTCGCCTTCGCTGCTTTCCCCAATGAGATTATCTCTCGCTTAGATAAATTGCAATTTACCGAACCGAAATTAGTCACATTAAATAATGAAGCGAATCAATTTTTAGGTCGAGACTGGAACGCTCATGAAAAACATCCTATAGAAATCAGAGCTTCTCACCACCCAGTTGGGCATGAGCGCCATGTTTCCAGGCTAATGTTTGTCCAGGATGCTGACGGCGAATATAAGGAATTCGCCATGCTTGAAACCAGAACTGCACAGCTTCCCATTGGTACGAAAGCGCTCTCTTGTATGGTTGGGATAGACCCTGCCACAGCATCAGCAACTATTGGACTGCCAGGAAACGAGCCGATTGAAATTACTATCCGTGAACTCAAGAACTTCTCTTATGCAGGACTTGTTTTCAACGCCGAATCGGTCAACTTAGAATTTGGCACTGTGCCGATTCCTGATAAAACAGTAAAAATCAAAATTGATGCTTTGACCCTGGGTGAGTTAGACAGTGATTCTGCCCAACAGTTAAAAGAAATTAATTATCTTAAAAATGGTAATCCCCTAAAATTAAAGCTCACGTCAATCTCTGAGACAGGAGATCAAGCTTTTGTCCTGGGTGAGTCTCCCAATGGAAATTTCCTCAAAATTAATAAAATTAACTTCTATGATTTTTCTGGTCAGACATTCAATGATCAAGATTACCGAAAACTGACTATTGAAACCTCAGCTTCTAAAACTAGAGATGCTGTATTTTTGAATGGTGAACCCTTGGGAGTATTACATTTCAAGAAAGACAAAGACGCGCTCAGACAACTTGGGCTACTCAAAACCGGACAACTTACACTCGCGCCTGCAATCATTGAAAGTAATTTTTCTGTTATTTGCGCTCAAATAAACCCTAATACCGTTGAATATCCCCAGAAGTGGACGAAGGAATTTCAGGCTTTTGGGACTCAATCAGTTAATCCTCAACAACAAGAGATGATTGAGAGTAGTGCGAAAATTCTCCATCATATTAAAGAACGTCCTACTTTCTTATTTTCGACAGAATCAAATAAAAAACTCGGAGTCATGGGCTTGGCTGTTGACAACCAGAAAGCTGAGACTGTGACAAAATGGTTAACTGCTCAAAAAGTTGAATGGCAGCAAGTACCAATAGAAGATGTTATCAGGGAAACTAAAAAAGGTCTAGCTGTATTTAACTTGGTTGATAGCTCCATCCCTGCCAAAACTTTAGAGAGCATGGCCAAGAAATTTGGGGCTGTGATTGAAACGGATAGTGAGTATCAACAAAGGGTTAATTCCCTCGCCACACGACCGCAGTTTTTGAAACCACCAGAACAAACAGCACAATCCCCACCTAACCAATCAACTCTATTACTCTCCACTACTCCTTTTACATCAGACATTAGTAATGGTGCGAAAACCGAACCTCTAAGTGTAGAGAAGCTCCCGACAGTCACTATTGATGACTTGAGAAATTGGTACAATGCCGCAGATAAGTTAGGGAAGCCGGAAGATTACAAAAAACGCATTGTAGAAGTGGCTTATGGGTTTAAAGCTGGTGAGCAATTATCAGCCCAAGCGTTGACAGTAATGAATCAAGATAAATTTGAACTTGAAGCCATCAGTCGGCTGACTCAAATTGCTCAAAGAATTGGCATGGTCTGGGGTAAGTCTGATGAAAATGGGATTCAAGTTCAAGGAAAGATTTATGATTTGGCTTTCAATACCCAGCAAAGGGATTTAACTATTTCGCAGAAAAATGGGGAGGTAATTTTAAACTTGCAATCTGGTCAGGTACAGACTAATAAACTAACTCCACAGATATTGCAAACTTTTGAGGATGCGAATAGTCAGATAGATAAAATTTTAGCGAAAAATAAAAGTCAAGAATTAGAAATACAAAGATAGATTTATCTGCCTCCGGCAAGGCAGAAGGCAGAGGGTAGTTCTTGCTGGAGGAAAGAATAAGTTTTAAATTTTGCCTTTTTGCCTTGCTAACTTGGGTTTAAGCTCCCTGCTAAATCGTAGATTTAACGGTCTACAATTACTGTTATTGTCAGAATCCCCTGTAATTGACCTTCTACCTTCTGCCTGAATTATTCATATCAAAGCCAAAGATGCATCCAATTCAAGCTTTACAGGTTCAAGCGATCGTTCCATGAATTCGTTTTCCTAGTCCCTGCTGAAACAATCAGCTTACGGCAATGCATGAGCTGATCGCTTGTGGCTTCTACAAGAAAACCACACCAAATGGTAAAAAAGTGTTTGATAAAAATGCGTTAGCGTTAGCTCCTCTGAAAGAGGTTCGCCACAAATTAAGCTTACTTTCAGAGTACCCCAACCGTGCAGCAAGGTTCAAAGTTCCAGCATTGTGGGTGGATGCTTGGTGTCAAAGGTGCTTTGTATCGTTCACGGAAATGGTAAAGTGGCGAAGGGTTATTCAGCGAGATGCGACAAGTCCATGAGACACTTACAACACATGAGATTTTAGTCAAAGATTGTGTCGGTTACATTAATCGTGTACTATTGTATTAGTACAAATATGCTGTAGTCTACGGTGAGCAAGCCAAAAAGTGTTAAAGATTGCAAAAAAAGCAACTATAATTAAGCGATAGAAATATTCTATAAAATCTTTATATTTTATTAAATAAAAAGGATTATGAATCTCTATATACATTTATATTTGTTCATTAATTAGACTATTTTGTGGCAGTTAACAGAGAGAAAAGTCATGTTGGATAAACTAATAAAATATTTTGTCTACGCGACAAAAGGGTATATTACAAAAACACAGCTAATCAAGTTTTTGTATTTAGCTGATCTTTACTCTGTTAAGTGGACAGGAAAGCAGCTGACTGATCTAGATTGGTGTTATTATCAATTTGGCCCTTGGAATGAAGGTATAGATACTGCTTTAAATCAAATGAATGGGAAAGAGATTGTTCAAGAGTCTCAGTATAATGCAACATATATTAGACCTGTGAATCAAGCTGCTCATGCAGATGATTTGGACATACCTCTCAGTATTAAGTTTGTACTGGATAATATTCGTAGAGAGTGGGCTGGCTCAGAGAAACTGAATCAGTTACTAGAGTATGTATATAGCACTGCTCCAATGGTGGAAGCAAAAAATACCCATCGACCAGAAGAGAAAGTTAAACTTAACTTACAAGCAGAAAGAGAAAAATTAGTCAGTGAATTAGGATTGTAAAGTGGCTGGAAAAAGACCTAGACAAGGTTGGATCTATTCTACAAATCCCTATAGGGTATCTCTTCGTTGCAAACTGGGTCATATTCATATTTATAATTTAGATGAGCCTGCTGAAGTAGAATGTCAAACTTGTAGTGAGAATATTAATTCAAGTAGGGTTTTTAGAGGTACACATCCTTATATCATCTGGACAAGTGATCAGTTTCAAGATGAATCTGGATATATAGCAACGTTTTCTGTTATTCCTCTGACTTCACAAACTACATTTAACGGTTTACCAACCACATATCCAATTAATTCTACAAGTAGAAATGGTCTTGATAAAAATTCCTACGCTTTAGTTCATCAAATATGTACTGTTGATGCTAATTGCTTTAAAGGCTCATCAGCCAATTGGTTAGAGAGAATTGGACAATTGGATAAAGCAGATAGAGAAGCTATAGAAGAACGTTTAAAGTATTTTTTGAGTATTCAAGAGAATCCTAGTGAAGACTGGTTTGCTCAAAATGCGTCTCCAGAACTTTTGAAAAAAATCTTTGATTATCTACCTGAAGATACAAAAAATTTAGTAATAGAAGAATTAATTAACAATTTAGACTCATAATACCTGTATATTCATCAATAACATTGATATTCTAATTATTACAAATTGGGCAATCTCTGTACTGCTGTTAGCTTGGTCAGTGCAAAGTGCGATCGCTGATGAATTAGCTCTCACTGATGGAATGGCACGCTAGATTTATGTGAAACCTGCTTGCTGACTATCTTGTTGGGGCTAGGGTGTAGGAAAAAAATCAAGAAAAGTAAATATCCCTGTTTTGTCAATCTGGGAGAAGCTAATCCCTGTAAGCCTTTCGCAGCTTTAGTTTTCAGGTTTTAGCTATAAATTTTAGTTACTGTTAGAAAATAAAGGTTCAAAGCTTGGCTCAACCAAAGTTTCAGAATCTTGCTTCGATTATTGTTTTCCGAGAGTGACAGAATAGGGATATGAGTGCAAACATAATTGAAGAAAAATTCAGCTATTCTGAATTCAGGAGTCAGCAATCTTGACGCTCTCTACGAGACGCTACGCGTAGCTTGCCACTCTTACAAAGTACGCAGACTCGCTTGCCACCGGCGCTATCCGCCAGTCATACAGAATACCCAATTGAATTCTGACTCCTGACTCCTGAATTCTGTTTGATAAACTTCTTTGCGGGAGCAACGCTGGCATGAGCATTACTACACCCCACACCAAAAAGCCTTATAAATAAGGGATTTGCCGTTATCAAGCGTGCCATTCGGCTATAAATCAAAGTCAAGGCTGAATGTTTCCGGTTCAGAATCTTCTTCTTTCTCTTGTGCAAATGGAGTTGAAGTCATTGAAGGAAGTTTGTTCTCGTCAGTAGTAATCGGCGTGAAAGCTACTTGTTGTGTGGCTAATCCAGCCTTGATAAAAACAAAATAGCAGTCAATTATAAAGTAAAGCGTCTCCAGGTAACTTTTACCTAGTTGTTGGGACTCTGCAAATATGCGTTCTCGATAGTTTTCTTTGAGCCGAATTTTTATCGGAGCTAAGTCAAGTTTTTCTGTCATTGTCATCACTTAATAGATGTAGTAGGCGAATTCTTGCTGCTGATGGCTTTTGCCATCTCTAAAAGTCCAAAGACATTAGCTTCCACCGGGTTGTCCAGTATTTTGAACCCGTTCTTCTCTAAAAGCTTTTTAAATCCGGGTAACAGGCAACCTCCACCAATCGCCCAGATTTCATCCCCTTGGTGTTTGGCATCAAGTGTCAGATTCACCACTTTCTTCAAGTATTTTTCATACCAATCTTTTAAGCAAGCGCTGTAAACATCTTTGATATCAATGTCCCGGCTGTAACGAGTATGCCCCATTTCCAGACAAAATCGGATCTTGGAGGCATCCCCGATTTTTCCGCCATTTAAATGCTTCATCTTTTGGGAAATATCATTGATGAGAACTTCTACACCAGTGGGGTAGGCAGTGTGAACTTCTCGTTTCCCTTGGTTGTAACGAGAATACAGAGTTGTGCCATTGCCAAAATCTAAAATGGTTAATTTTTTTGGTAGTTGATGCCCAAACAATGCACCCATCCCTTCTAGTACGACTTTCAGGACTTCGATCTTCACCTCTGATTGTTTGCCAGCTAGTATTGGCTGATATTCCCCGTTTAGTACTTTTTGCAATTCTTCAGCCAGAGCGACATCATGTAAGCTAACGACTAATTTTAAATGCCAAGCCTTACGGTGTGGTAGATGTGCCAATGCACCGAATAAAGTCAATAATGCATTATTGACTTTGTTTTCATTGTTATCAGTGTTTCGGTCAAAATAATTTCCTGTACGAAAAGCTGATTCTCCAACTGTGTAAGCACTACCGTTAAAAACGACCCTCCCTGGTACGTCTTCCATCTCGGCATTGGTTATATAGCTGGGCACACGAACAACTTCAAAGCCATCGACTAAAAGTTTTAGGCTTCCATAGCCGTTATCAAAGCCAGCAGGAAAAATCTTTTGCAAGGTGTGAATGTTAGACATAGAGAGAGGTAATAGATTTTTATTTGTGAAAGTTATCTGTTGAGGTGAAGTGGGGAGCAGAGAAGAGATGAATAAAATAACTACTCTTTTTTTCTTCAGCGTCAAAAAATTATCATAACCTCTTGGGGGCTAAGTGGGGTAAAACCTCACTCAATCGAATGTACCCCACATAGCCCCCACATAGCCACCATGTGGGAGTCAAATTTTGCTCAAGCCTCTAAACTGCTTTGGGGTACATATAGCCCCCACATAGCCCCCATGAATTTTTTTGAAATCTTTTCTATCAACGCAGCAAAAATTAATTTAGATCATCGTTGACCATTTAATGAAATTCAAAATTAAAAATTATGTTAGGAAGAATAAGAATAATTTTGAATTAATTCTGGGTACAAGCCCCTACTGATTTAAGAAATCAGTGGTCTGCAAAAAGCGACGCTAGAAGACTCGCTTTCCGCGTTAGCGAGTCCACGATAGCGAGTCTTCTAGCGTCTTGTCTTGTCTTTAATTTTGAATTCCCCGTTCGCGCAGCGTCTCGTAGAGAAGGGGTTGACAGCTTGATTTATACTTTAGTGTCAATAAGATTGTTGAGAAGTAATTCAGTCTTGCTCTCTGACTTCTTGATTACTATGTAACGAGTGCGTTATTACTTGCTTACAGGTTCAGCTTTCTCTACTGAATTATCATTCACACCCAAAGTCAATTCCAAAGGAGTTTTTTGAGGGTAAGCTTTTACTACTTGCCGATAAACATCATAGTTAGTAGGTAGCGTGTTCTGAGTATTACCCACTCCATAGGTCAGTTTGTACTTTACATCTTTAATCAATTCAGGTTTACCTGCCTCTTCTTGAGGTCTTTTACGTTGTTCAACTTCATCAACACTTGGTCGCGGCGGTAAAGTAGGCCACCATAGCCCTTGGTCATCTGGGCCAACAACTGCTCCTGGCGGTTTCAATCCATTTCGATTCAACATTGAAGTATTAGCAAAAGTTTCAATATATTCGCGGGAGTCCCTACCTTCAGGGAACGGAGAAGCAGTGAAGCGCCCTTTGCAGTGAGCAAGGTGGGGAGGGATAGCGACGGGTGACGGAGGCACGGAGTCGCCCACTCTCTTCTATCTCGACACGCAGAGTCTAGTACTGCGCTGCAATAGTTCGACTTTTGAGGCTTTGAATTGTCCATATCGTCTCCAATTAATGTCATAAACGCTGACAACTTTTGTAGCTTCGCTGTACCCACCAATCCAGCCCAGAACAGTCTTTCCCGACTTCTTTGCTCTAACCAAATCACCAGACCTGAACCCAAAGGGTGTAATGGTGCCACCCTTGCGCTTACGGTTTCCGGTCACGCCACTGACCGGATTCTCAAAGTGCAATTGACGACGGTAAAGATTGGGACGGCTGATGACCCGAAACACCGATTTTGTGACGGTGACTTGACCTTGCCAGTGATGACCGCGCCCATTGCTAGATTGAAACGACTGGTATGACATAAAGTGACTAGCCGCCAGTGCGATGCCGTCATTGGCATGAGTTTCAGGAATCTGCTTTGACTTGTCACCCTTGTCTTTAGCCAGCCCTAATTGCCGCCTGAGCGTCGAAGTTTGCCACCCTTCCTGAGAAACAGTCGGGCAGAGTTCTTCTAGCCACTGAAACATGAATTTCTGTCCGACCATCACCGGAGAAAAGCCGCGTCCTTTACCCTTTTCAGTTCTGGCTTTGACGACCTCATAGCGGATGTCAGAGACGGGGAAGTGTTTGATTAGCTCTTTCGTAACCCGCAATTCCATCTGCCTGTTGGCTCGAATCGAAGGCGGCAATTTACCCTGCCTTCGATTCGAGAAGCGCTTTTGGCGATGCGCTCTGAGATGGAATGCCACTTTGCGGTTGATACGTCTGGCACGTCTGGCACGACGCAGAATTCGGCGACCATTCATCTTCTTTGTAATTGCCTGTAAGGGCAGGATGAGATGCGCGGTGAACAGCGTAAACCTGGATGACTGAACTCCAATACCCGTGAACATCTTGCCGGGGTCGATGCCGAGTGCGATGTCTTGAACCTCGTAGCCTGATGGCTCGCAGATTAGCTGAACGCAAAACAGATTCAGGTCGTTGTGAACGACTTTTGCCTTGCCCGCTTTGAGCCAGCGACGAGCGCGGCTGGGTTTGGTGGGCATAGCAGGAGAACCGTCTGGATTGAGAACTGAAACGCGCATTTTGGAGATAATCCTTATCGCTAAGTGAGAAAGTCCCTTCGCCCACCATCAAGATAGATGTCCTTTCTAAAAGCACCGATAACCAGTCGGTTTAGAGGCAATCCGAGTTAGGGAAACGCTCGGAAGTCTGTGCTATCTCGTTGGCTCGTTGGGCTAGTGCAACGCTTTGTTAGAACCTGGCTGTTCCAAGCCCTATCCTCAAAACCCGTGGCGCGGAGCGCTAGGGTTTAGGGTAGGGTAGTTGACTGCGTGGCTGTGGTTGACTAGTTAGGTTATTCGCATACAAAACAAGCCAGGTGTAACTGGTGAGTGCTGTAGCTTCATACTGTTCAACAGTAGTAGTGCTGCAACTAGTTAGTGTCAGTGCCGTTAGTGCAGTTATTATTGAGGGTAAAAATTTCATTTGCATTATCAATCGTAAATATCTTTCACCAATCACTCTTGAAGAGGGAGTGTGCCATCATTCCTGCCAAGGTAAAGGTATCGCTGTTGTTGAAAGTACTTCCCTTGCTTGCAGCCTAATCGCTGTTTGCTCACAGTTGGGGCATTTTACTTTTGTGAAAATTACTTAAGGTCGTCCTTTGTACTCGCCCATTACGGGATCTCTGGTGTACTCGCTGATTATCCCCTGCTTGCAGTGATAGCACTCGAATATTACACGCCCTACCTCCGAGTTGCAATCCAGGAATTGCAGTGCTGACAGGGTTCTGGCGGTAATTCTGGTTCTTCGGGGCGGTCTTGAAAGGGTATATGAGGTTTGGTTGCTGGTGGTGAATCTATTTTTTTCTTGTTGCGCTTGCCAGTCACCTGCGGCTCAACTTTTGGCGGCTTCATGGGTTTTTCCTCGACAGGGGGATAGTCAGGCTGTTACTGAGTTTTGAGTTATTCATCAACTAAAGTCAAATCAGATTTAACAGATGAGGTAATGGGTTTGGGCTGTTGCTGTTTTGATGGTTTAGATGGACGTTGGGTTGATTTCAATTTAATTTTGTTTATTTCTCAATCCTTAAAAAATGTGTCGTATTTTAAAATACGACAGAAATAGGTGACAAATACAAATGCATGATATACATTTTTCAAAAGCTTAATGTCGAATTTCAAAATCCGACAAAAAAACTGATATGAAGCAGATAGTTCTCTCACTGATAGCTAACGCAGGCGGTGTAGGTAAAACTACACTCAGTGTACACCTTGCATACGAGATAGTTCGGCGTGGCTTTTCTGTAGCAATACTTGACTTAGATCCACAACGCTCTTTAGATGTGTTTTGTGGGATACCACCTGCTGAAGTATCTAATACTCTAGTCAAGGCATTATCCAAAGATTTTAAGGGGGATTGGAAATTAATTTCGGTTTGGGAAGAATCAAAAATTCAAGTCTGCCAAGGACATCCATTAATGGCTGAAATGGCCAACGAATTAGTAATTAGGAAACGAGGAGAGTACACACTTAGTGATCGCTTAAAAAACTATCCATTACCTCATAACTTAGTAATCTTGGATTGTCCGGCCACATTGGGAATGCTGAATGTTAATGCTTTAGCCGCTTCAACTCACATATTAGTTCCAGTGCAATTAGAAATGAAAGCGATTTCTGGTTCAGCAGAATTGGTAGAATGGTGCATTTCAACCAGCGATGAGTTACAGTTATCACCTCGTCCACCAATTTTAGGGTTTGTGCCAAGTATGTATGATGATACCGTAGCGATGCACAGACAATATCTAGAGCAATTACCAGAAATCACTGAACATTTACAATTAAAACTTTACCCCAAAGTTCGTAGTTCCAATGAATTCAAAAATGCTAGCGCTCACGGGCTACCTTTACAAAAATACCGTCCTAAACATCCTGCTTGTAAAGATTTTAAGCAAATTACAGATGATTTAGTCGCATTAATTAAGGAGAAAAAATAATCGTGGCTTTGCCTAAAATTGCTAGTAGATTTAGTAGTGCAGTTCAAAAAACTGAACAAGAACAAAAAATTGCTGAACTTCAAATAGAAATAGAAAGGCTCAGAACCGCACAATCTCCTGAATTAGAGAATGAACTGCAAAAACTCCGAGAACAACTTCAAAATCAATCAGGAGAAGTACAAGTTGATTTAAATCTCATTGACCCGAATCCTAATCAGCCTCGGCAGACAATTACACCAGAATTAATACAAGCAAAAGCACGATTACTCAAAAAACACGGGCAGATTTCAGCAGTCATCTTAGTCAGACAGAGTAATGGTCGTTACATACTGTTAGATGGGCAGCTACGTACTGAAGGAGCTAAATTACTAGGCTGGTCAACTATTCGTGCAGTAATAGTGGCAATGCCTAATGACTTAGATCAATCTGCATTATTAACTTTTCTTGGCTTTGAAGACTTGAATCCTTTAGATAAAGCAGAGGCAGTATTTAAAGAAGTAATGAAGTCCGCTAATTTGTCAATGGATGAAGTTTCCACAATGTTGGGAACGGTAATTAAAAGAATAGAGAGAAATGGAAATAGTAAAGAGCTAGCAAAATTGATGGCTGTTAGCGTCGATGAACAGCAACAGGGCTTAGAACTATTGGAAATTACAGGCAAAGAACAGAGTCTACTACTAGTGCTGCTAGAGTTAGGGTTAAATCCTAGTTCTGTGAAAGCTAATCTAATGCCGATGCTTTATCTGCCTGAAGATTTAAAACAGGTCATCAGGCAGCATGGACTCAAAGGCGCTCATGCTTTAGCATTGGCAACTTTATCTGCCAAGGCATTAGACATCTCCGAAAATCAAGCAGCATCAGAACGGATTGCAGCAACAGATGAAGTCTTAAAGAAAAATCTGACAGTAACAGAAACTCGTGAACTGGTTAGAAAAATTAAGATCAAGTATTTAAAGTCAAATGAACAAGAGTTAAAAGAGGTAAAAATAATATTTCAAAAAGTTAATGGAATTTCTGGAGATTTGCTTAAAAAAGCTAGTAGTAAACAACTTCACGAAATGCGCTCTCTTTTTCAGGAGAAATTACAAGAAATTGACAAAGTTATTGCTACAAGTAAATAAATTCCATATTCTTGCTTTTACTTTTACAAATTGTTTCATAGAAGTAAGTTAATCGGAGAAATTAGGGTGAGTTTTCGATGACACTAATACTGGGTGTGTAGTTTAGTATTTATGTACTATATTTCATTGAATTCCAGTATTATATACAATAATGTGCTGTGCGGCATCTGAATCATAAGCAATGTCCACTCCTCCTAATCTTTCCCCTCAACAAGTAAGCGCCTTTCCTCAACACGAAACAATCACCGGAGTCGTAGAACGCCTAACTTTTTACTCTGCTGAATCGGGTTACACTGTGGCAAGGCTAACCCGTCCCCGTAGCAACGAACTGACAACAATTGTTGGCAGCTTTGCTAATATCCAGCCAGGGCAGACTCTACAGCTAATTGGTTTCTGGCGTGACCATCCCCAATTTGGGCCACAGTTCCAAGTCATTAATTACCAAGAAACCAAACCAGCCACTCTCACTGGAATTGAGAAATACCTTGGCAGTGGGCTGATTAAAGGTGTAGGCCCAGTAACAGCCAAGCGTATCGTCGCTCACTTCGGTTTAGAAACGCTCGACATTATCGAAAACCAGATTGAACGACTGATTGAAGTCCAGGGTATTGCCAAAAAGCGAATCACTCTCATTAAAAACGCCTGGTCAACTCAAAAAGCCATCAAAGAAGTAATGGTATTTCTCCAGGGGCATGGCGTTTCTACCACTTATGCTGTGAAGATTTACAAGCAATATAAAGATGAGGCGATTGCCACTGTTACCAAGAACCCTTATCAGTTAGCAGCCGACATTTACGGGATTGGTTTCCTAACTGCTGACAAGATTGCGAGAAATATCGGAATTGCACCGGACTCAGAATTTCGTGATCGTGCGGGGATTGTCCACTGTCTAAGTGAAGCTGCCGAAGATGGTCATTGTTACCTGCCACAAAGCGAACTGATTGATTCGGTAATCAAACTGCTGACTACCGAATCTCATCAGTCCACAGAAGAAGCGGTTGCGATCATTATTAAAGATATGGCTCTCGCAGAGGAACTGATTAGAGAGTGGGATGAAGAAAAAAGGCTACTTTGCTATAAGCCGACTTACTTTCATACGGAACAGAATTTAGCTCAATTGATACGCCAACGCTTGGAAAATCCTGTTGGCACTGACATTGAGCGTGTGCGTGATTGGATTGACCGCTTTACAGCCAGCCGTAAAATTCAGCTTTCACAACAGCAACGTCAAGCTGTAGAAACAGCAGCCTACTCCAAAATCATGATTTTGACTGGTGGCCCTGGCGTTGGAAAGACCTTCACAACTCACACCATTGTCACTGTGGGCCCAGGTCAAATACTTGCTGATTTGATTAATTCTGGTTGCGTGCCAGTAGTGCGGTTAACTCAGGTATTCCGCCAAGCTCAAACAAGTGCAATTATCACTGCTGCTCACCAAATCAACCGGGGCCAGTACCCAACAATCGAGCCAATCTCCGACAATCCTGTGTCTGATTGTATTTGGCATGGTGGAGGTCATCAGCCTGAACATGGAGTGCAAGCAATCTGCGAGTTGATTACAGACTTGCTCCCTCGACTAGGTTTTAATCCTGCCACTGATGTCCAAGTGCTTTGCCCGATGACACGGGGAGTTGTGGGTACTCGCAATCTTAATACCGTGTTGCAGCAGTTGATTAACCCACCCAGCCCCAGCAAGGTGGAGATTAACAGAGGTGGGAATTTGTTACGCGAGGGCGATCGCATTATCCAGCTAACCAACGACTACAACCGCGAAGTTTTCAACGGCGACTTGGGAATAATCCTCACCATTGATACTGTCGAGCAGGAAGTTACAGTGCAATATGGTGAGCGGACTGTGGTTTACGATTACGCTGACCTGAATGAAATTGCCCTTGCCTGGAGCATTTCGATTCATAAAAGCCAAGGCTCAGAATATCCGGTGATAGTTCTGCTAATCTATATGCAGCACTATATGATGTTGACCCGGAACCTGTTTTACACTGGTATAACTCGTGCCAAGAAATTAGCGATCGTAGTTGGCGCAAAAAAAGCGATATCTCTAGCGGTGCGCTCTACTGATGACCAACGGCGGTACACACGGTTACAGCAGAGGTTACTTCACCCAGGACTGCATTGGTGATGAATTTTGATTATTAAAAATAGAAAAGTTTATCGAATTATTTGATTTATACTTTTAAATCGCCCGGTAAAAAAAGCCCAAAAGTTTGTATGTCCAGCCTGAGTTCAGACATGGTTCGCATCTATTTACAAGAAATTGGTAAGTATCCTCTATTAAAACCAGACGAGGAAATTGCTTATGCAAGACTTGTACAAGAAATGATTGCCATTGAGCAATCTAAAAATGAACTCACTCAACAGCTAGAGCGTGAACCAACAATGACAGAATTAGCCAACACTGTTGAAAAAACCGAAACACAAGTCAGATCAGCACTACACCTTGGTCAAAAAGCTAAACAAAAAATGGTGACAGCTAACCTGCGACTAGTAGTTTCTGTTGCCAAGAAATACCAGAACCGCAATTTGGAATTTTTAGATTTGATCCAAGAAGGAGCAATAGGTTTACAACGGGGTATAGAAAAGTTTGACCCGAACCTGGGGTATAAGCTCTCGACCTACGCCTACTGGTGGATTAGCCAAGCTATAACCAGAGCAATTGCAGAACAATCCCGGACTATTAGATTGCCTGTTCATCTAACCGAAATCCTTAATAAAATTAAGAAGGTGCAGCGAGAAAGCTTTCTAAAACTCGGCCGCCATGCCACTGCTGAAGAAATAGCTACATCATTAAACATCAGCCCCGATAAGCTTCGAGAATATCTCAGTGCCTCTCGTACAGCCATTTCTTTAAATAAAAAAATTGGAGATGAGCAAGAAACAGAATTGGGCGAAATTTTAACAGACGTTGGTGTTTCACCAGAAAAACTCCTTACCCAAGAACTTCTATCCCAAGACGTGGCTAAATTCTTAGAACCATTGACACCTATACAGCGTCAAGTGTTGACTTTAAGCTTTGGGCTAGAGAATGATCAGCATTTCAATCTCGCTCAGATTGGCCAACAGCTAAACCTCAGTCGAGAGCGGATTCGTCAAATCCAGGTCAAAGCTATAAGTATTCTCCGCCATCGACAAAGCGACATGCAAGAGTATTTAATTGATTAAGTAGAATTACTTTCGTCAGATGATGCACGGATCTTGTAGAACTAAGACGAAAAACTATATTAAAGAAGTAATACCAATTTAATATGAAGCTGCATAGAAAAGAGCTTCGAGAATAAAGTTATAAGAAGAGATAGATATTACCTGCTCAAGTGTAAGTTGATTAAATATTTCTTGGATGCGATCGCGTAAATTCTGTAAAGAAGAGAAAAGCTGATTTTTGAGTGGTTTCTTGAGGAGCTGCCAAAGCCTTTCAATGGGATTGAGTTCAGGGGCTGAAGGTGGTTGAAACAGAGGAATAATATTTTCTGGCCAACGAATTGCTGAACTTGTATGAGCAGGTGCTTGGTCAACCTGTAAAATAGCGTAATCCCCACCTAATTGTTGAGATAGCCAGTCCAAAAACTGTTGAAAACACTCGCCATTCAGTTTTGGATATTCATAAAGAAAATGATCTCCAGTCAATGGTTCAATTGCACCATAAATCCAAAAATTTTCCCGTGGCCATTTCACCTCAACAGTAGGCTTAACTCCAGAGGCAGTAATCACTTTTCCTGTAAGAGTTTTCAGTCCCACCCTCGTTTCATCCTGGCACAGGTAGCGAACACACTTGCCGGGTGCTAGATGTTTTTCTAGACAATTCAGAATGATACCGAGTTTTTTTTAAACTCAGATACTAACTTTTCATCCTGCTTATGGCTTTGAGGACGTGGTACTTTTAGTTTTGCCCCTAATCGATATCGAACCAATGCATAAACCGTTGCATACTCGATATCAAGCCCCTGCTCTTGCTTTAACCACTCTACTATTGCACCATAGCTACTAAAGCCTTTTCCTGTTTTTAACTCCTCTTCAAGTGCCGTGATCGCTCCTTCAGGAATTTTCCGTTTTGCTCCCGGAGCTTTTTTTATTTTCAATAATTCATCTAGCCCACCCGATCTATATTTTTGTAACCATCTTGTCACCGTTGATGTATCTTTAGCCAAGCGTTTTCCAATATCTTGCTGCTCCTTGGCCTGCCCGCTTTTTATCCACCACAGCATAATAAGTTTTTCTTTCTGGTTCCCTAAATTAGCTGTTTGTAGGCGTTTTTTAAGTTCTTCTTCGCTCTCTGCGATTTCAATCTCAAAAGGGCGGCTCATGGTTCTTTTAATTTATCGAGTTTGTTTTCTCTATTATATGCAGCTTCATATTAAATTGGTATAAGTCCACAATAGTAATCAGTCAACAGCTTAAGGCTGACCAAGAAAGTCTCCTTTGCCAAGTTCTACACCACAGTGTCTAAGAATGTCATAGGCTGTTGTGACATGGAAATAAAGGTTTGGTAAAACAAAATATAGGAGAAATGGCATTCCTTGAAAACAGAGAGTGTTGTCACGCATTTGCAGGGTAATTTCTCTCTCTTCTGAACCATCAATTTGCTCAGGTTTAAAAGTATTTAAATGAGAGATAGTTTTTTGAATACGGTCAATAAGTTGACCAAATGTAGTTTCATTGTCCTCGAATTTAGGTGGTTCTATTCCTGCTAACCGTGCGGCACCTCTATTAGCGATGTCAGAGGCAATCTGCACTTGTTTTGATAATGGAAACATATCTGGGGATAGACGACTATTAATCAACACAGAAGGGTCTATTTTTTTAGTTTCTGCATAAGCAGCACCTTTTTCAAGAATGTTTATAAGGTTATTCAGTGTGCGAATAGACACGGGTATTAAAGCTTGGTACATTGAAATGGTCATTGAGATTTCTCCAGAAAAAGTTCAAACGGCTTTGAGCCGCCCCATCTAATATTAGGGGGTATTGACTGTGATATTGTGTCAAAGAATATGGAACCGAATTTAGTCATAGATCCAAAGATACTAAATGTTTCCCCATAGTTAGTAATCCCTGGATGCTCGATAAGAGTTAGTTTTTTTTGCTTGGGAGGAACTGACCTTTGAGCGATCGCTTTTTGTGCCCAACTTTATCACGCCATCCATTCAGTCCACTGCGGGGCATCTGTCATCAGTTGAGACAAACTTTTTGAGGTAAGCATCCTCAAACTTCAGTATCATGGCGCAATGCTCATTATTGTTTGCTGATTTTGATGATTTGCTCCCGCAAGTTAAACCGTAGCGCTCACTCCCTACTATCAACACATCCCCACTAATTTTTTTGACTATAATGAATAGTTTGACAGGATTGGCAGAGGATGGACACATGGGCTGGGAACTCCAACTGAACGCGCTCCCCTCGAAATGCACCTTACTCGAAAACGTCGTTAACAGTGACATTGATGCCGAATATCTTTTGTTTGTACGGAGGTATTTTAGCCTGCGCCGCGAACAGCAAAGTCGGGTCAACAAATTTCCTTATGGTGAGGCTGAATATAAACAGTTTGTCGATGCCCTTGAGGAACTCGTCGAAACGCACTCTGGAATTGAGAATCGATACTGCGATCTTTCTAGGCGATTCGATTGGATAAAATGGTTGCTGATGAAATGCGCTCTCTCCGAAGAGGAGGAATCGTTGGCTGTCACTGCAATCACCGGCCAATCAAACGTGTTACCTTCTGCACGAAGCACACAAGGATTCCCCATCCGTTGGACTCCTGCCGACAAATGCGAGTTGATTCACATTTGGCTTAGTGGAATTACTGAAGAAGATATCAAGTCCAAGTACGCTCCGGTACTTATGTACGATGCACACCTTTACAAGTGGCACCAGACGAGGGATACTGACGAGGCATTTGGATGGATCGTCAGGGACTTCACGGCACTCAAGCGATTCTACGAAGATGTGGTAGATAATTCAGAGGCTGTTCTTGTAGTCACCGACTAATACGCTTGGGTGAGCATGACTACTAAGGTGATTTCTAGGAAAGAATTTACCAATAGAGGTAGAATGTAGCCTTGATGCAAAACAAACAGGAGCAAGCATTTGGATACGTTAGCCACAGCAGGATTAACAGCATCGCAAATAGAAGACTTGCGGTTGGCAGCATCGAAAATGAATGGAGTGGAACGTCGGAGTTTTCAGGCACAGATGACATTGAAATATTGCCAGGGAAGCGCAAGGCAGGCAGAAACAGTATTTGGCTGGGGTAGACAAAATATAGAGGTAGGATTGGCAGAAAAACGAACAGGGATAACCTGTGTAGGATTACAGTCAACCTTTAGCGGAGCAAAGCTTTGGGAGGAGAAACAACCGGAAGCAGCATTGTCACTGCTCCATCTTGCAGAATCTCATGCTCAACAAGACCCGACATTTAAAACATCATTAGCCTATACCAGACTAACAGCAGCATCGGCATTGAAAGAGCTAAAAGAGCTTGGATTTAGCCCGGAGCAATTGCCAGGAGCTAGTACAATGGCACAAGTATTGAACCGAATGGGCTATCGTCTTCGGCTAGTTGTAAAAGCCAAGCCTCAAAAAAAATACCACAAACAGACGACATCTTCAACAACATCAAAGACTTTCAAAATCTTGCAACAAGCGAATCAGTTAAGAGACTAAGCATAGACTGTAAAGCCACTGTAAATATTGGCGATTATTCGCGTGGAGGAAAAACTAGAGGCGACAATCAAGCTAGCGACCACGATATGGGATGCAAGGAAAAATACATTCCCTGTGGGATTGTAGACGAAGATAATGGGCAACTACATATTATCTTTGGTAGTTCCTATAAAACTAGCGATTTCATTGTTGATAACCTGATTCATTGGTGGAAAACAATTACACCAGAACAAAGACAGGATACCGAACTAATACAAATTAAAATTGATAACGGTTCCGAAAGTAGCGGAGTACGAACTCAATTCTTAAAAAGAATGGTTGAATTTGTTGACCAGATACAAAGACCAATTCAATTACTTTATTATCCTCCTTACCATAGTAAATATAATCCCATAGAGCGCTGTTGGGGCATTCTTGAACAGCATTGGAATGGAACCAAACTTGTTGATGTTCAAGTTATGCTTTCATGGGCTTCTAGCATGACTTGGAAAGGATTACATCCAATTTTGACTTTAAGCAACATTGTTTACCAAAAGGGGATTTCCCTGACTAAGAAAGCCATGAAGCAAGTCGAGTCTAGATTGCAGAGAAATCCACTTCTGCCCAAATGGGATATCTTGATTCAACCAATTTAGGTGGTAAATTATTTTTCGGAAATCACCTAACTAGTTTTTGCAGCTTGTTTTTGGTTGTTCTCTAACACCGAGAAGTACTGCCGAGCGTTCAGGGGCTTCTTCCACCAAGTGAACTCAAACAGGTATTCATCTTTCTTCAAAGTTAAGCATCGTAACCCATTGATTGATTTGACTGCCGTTGATTTTATCAGTGGGGGTTGATTTGAAAGCCAGCATGAAATATCTTGTAATAGCTCTAATACTGGTTGCAGTGCTACTGCCAATAGGCATCAGTTTGGCATCAATTCCCAGACTCCATTTTCATGAAAACCCTGACAAGATGGAGCAAGAAGTTTTGCGCGTTATTCTGCTAGGGGCTGCCATAGCTGATGCAAAGAAGATTATGGAGCGCAACTGGTTTAAGTGTGAAATTTATGAAAATTCAACTTTTATCAGATATAGAAAAATCCCTGGTAATAGTGAATCCGAAACAAAGTTATTTAGTCATGTAGATTTTATTTTGTGTACGCGCAAAAAAGGATTCATAGTTAAGCAAAATTGGATAGTTGGTATTATTTATGAAAAGGAGCGTGTGACAACTGTGGTAGTAAATTACGGATTAACTGGTTCTTAGTGGGGTAGCCACCGAGATACCCACTTTGGGGAGGATAAAACTTTGCCCTGCTTTGATAAAAACACTCTTGCACCAAACTTGCGAAAATGCTCCTCATCAATGGCGATACCAGCCGCCTTCATCCACCGAGAAGCTCCCTTCCCCACGGGAATATAATATGGTATTGCCCATTTCTGGGCTTGAGCGATTCTTCGAGAACACCGCAGGTATCGCAGAAAATTTTGGTGTACCGAATGTATCTTAAGTTGCCAAGGATGTGATAGCATACCTTCAACAAATTTAGATAGCATACCCAATCCATGAATCAAGTTCGACTCCCCAAAGTTAGCGTCGCCGTGATTGGTTTGGTAGTTGCAAGCGTATTTCATGCTACTCCCGTACTGGGAGCGATTCTAACTAGACAAGAATTTTCAGGTGATTTTACCTTAGTCGATGCTACTAGCCCATTCCTTACGAACTCTTTGCCATTCAAGAGCGAATATTCTGGATTCGTGGTTTACTCAGAGTCCGGGACTTTGAGCGATTGGGAGCTATCCGTCAACAATCTAGACCTAAATTTGAAGAGAGGCTCTACTAATGGCGGTAACTTAACCCCAGATGTTGATTTTGAGTTTGGTTCTGGGTCGAATTGGAATTTAGTAGTTGATTTTGGCATTGCTTTTGATGCTCCAAGATATACCTTAGAAAAAACTTCAAGCTCTGAAATTAGCTTGACGGGTGAAGTGGGACGGGCTGGAACATACATTTATCAAGATTCTGCTGCCAATATTACCTTGAGTTCTTCATCTACATCAGTACCAGAACCTGCTTCCCTACTAGGTTTATTGTTTGGAGTTGGTGCAATTGCTGTCTCTAAAAAAGCTAGTGAGACGAAATAGTAAAGCATGAATTACTGAACTCTTTACCAAAGCTTTCTCTCACTACACAGCTTCTAGCCAATCGCACACCACAGACCTACATTCCGTGGCAAACTTAACCCAAACCTGCCACTGCCCCAAATACCCATTCCAGTAAGGCTCACTATCAGCAACGCCAACAGCCTCGCCAACTTTGGAGATTAACTCGCTGTAGAAGGAACCAGCGCTATTTAGCCCAAGCTGCATTTTCACCATCAGCCCCTTCCATCCAAGAATCGCGATATTTTCTGGGGTATGTGGTGCTGTGTCACTGAGTGATGTTGCAAAGACTATATTATTAGTGCCTGACACCAAATCAGTATTGTGCGATATGGATAGTGATGTTGTGTCAGTTACTGGTGTAGTTGTACTTAGATTATTAGTGACTGACACCGATTCCCTTGAAAACGCTTCATCCCGATTAAACCACTGCCCAAAAATTGAATTACGCTGATCATTAGGGGCAACAAACCGATAAACGCACTCCCGATTTTCACGCTTACCCAAGCGACCGACGTAATCGAGTTTCAAATCAATCTTGGCAAGTAATTTCTGTGCGATCGCTATCGGTGTATGTTTTTCCGAGATACTAACATTCAAGTAATTCTTGATAACGTGCCGATGCTTTACAGCTAGCGCTTTAAACTCCACCATCTTCTCATCAGACCCCCGCAACTGAACGTCTGGTGTAATAAACTGCAACAGATTGAGATTTTCCAGTAACAGTACAGCAGGTAATAGCTGTCCCTTGTTAAAATCTGGTTTCCAAACCGAATTCTCCCCAGCTTCTAACTGTGCCTTAGCCCGTTTAGCATCACGAGTTGTCAGAAACTCTCGCCCCAGTGTCAAATAATAGTGCATCCGCAGTTGGGGATACCAGCCGTCGTCATCCTTCTCGACCAAATCAGGTGTTACGTCAATTTCGTAGCGGCGGGACAATTCCGCCTTGCGCTGCTGGTGTCGTTCGGTTTTCGTTTTCGCCCTTTTATCTTGCAGCTTTTTCAATTCGGTTGGGGAGAGTTCATCGGAATCCGCGATCGCTTTACACTCCGCAGCATATAATTCAACAGATGCCGCCTTAACCGACTCGATTACTGCGCCAGTCTCATCATCGTCGGCATCTGAGGCATCAATAACGGTGTACCCATCCTCGACCAATCCCGCAAGCACAGACTCTCGATAGCGCCGCATCTCAACGTTGATGACAGAACCACGCTTACCCCAAGTCTGCAATGACTCCGGTTGAAAATTCTGGTCAATAAAGCTGTAATCGTCATTATCCGCCGCCGACAACAGCGCAATGTTCGCCTGTGTTGCGACGTGTTGACTTCTCAACAAACCTCCGATGGATGTGGAACCATTGCCCACAACCGACATCCCCCATTCTCTCACCCAAATGTGACGGTCAACAGTTTCCCTAACCCGTGCCAACATCTGACGGACGGAGTTAACCGGCTGTACTCCCTGAAAAATCCCCCAAACACCATCAAAATGTCCTCTAATATCGATGCTGACCCCAGTTTCTAAACTTGGAGAGGCGATAACCAAATCGTACTGGGTGAGAATTTCGTTCAAGTGGGCAATACAACCGAAAGCCGCATGAGATGGATCAGCAACGGATTCACTGTCAATTCTCAGTATCCGCAGGTGTGGGAATTTACGGCGAAACCGTTCCTCCAATGCTTGGGTTCCCCATTTAGACTTTGCCTTTTGAGCAGAACAGCAGAGTAAATGATGCCCACCTTTGGCGATGGCCTTGTCCAGTGCCGCAATCAAATTCTTCGGGTTACTCCCAGAGTAGTTGTAACAGTTTCCGGCTACGTGCCGATAGTTGTTCACGATTACGAACGGATTAACCCGATATTCGCCAGCGAGTGATAAAACGTACTTTACATCAGTATCTGACACATCAGCACTAGACAGGTAAATCTTTCCCTGACTGCTGCCCAAAACATTCTGTACCAGTTGTTTGAGGTTTTTGAGAACAGATACCCGACGCTTCTGCACTTCAGTACCAGAGTTAAGTAAATGCCAAAATACTTGGTCGCATTCGTCAATAATAATGACATCATTTGACCAGTCGTTGGGATTGAAACGGGCTTGGCTCTCATGATGCAGCGAATCTACACACACCCCATATCCTAACAATGTGCCTGTTTCATTCGTGCGGACTTCGGTAACATAGTTAACACCGAAGCGATTACACAGTGCCTCACCTAGTTGAATGCGATGGGTGATAATTAATACCCGTCTCTCTTGGTCATGTGCTTTTGCCACTTCCGTTGCCAGCCATTCGGTTTTACCAGTGCCTTTGGGAGCCTTGAGGATAATCAGCTTTTCACCTTCGGGGACGAGAAGCTGGCCCAAGAAACGTTGGTTGAGTGCGATCGCTGGCGGGTAAGTCAGCAGAGTGAACAGCTTAATCTCCCATAACTCCAATGCAACGGCAGTGTTGTAGAGTGCGTCAAATGCCGGCTGACCATGAGCGACGATAAAATCATCAACCCCTTTCTCTGCCCCGAATGGTAAATCAATCACTCGCAGCGAACAGCCCTCATTTACCAGCAGCCGTCCCATACGACTGATGGCGGTTCTGACTCGCTGGACTGTCTCAGGTTTGTTGTCCTGGTCAAAGCAGATGTTAACCTGTCTCCCCTGTGTTGCAAAATGCTTCAAGTCTGGGATGAGGTTTGGCTTACCAATGGCAGTACCGTACTCATCCTGGGGTGTGCGGTATCCAGCGTTAACACCGGGGATAGCGATCGCTGCATAACCAGCAGTCAGTAATGCCCCCGCTTTCTTGACACCTTCAACAATTGTCACTGGTACGTTGTGCCGCCAAACCCAATGCCAGAAACCGCCAGGGTGCTGCAAATCTTCTTTGGTGATGGGAATACCGCTACGATTAGAAACTTTCACCCAAATGCGATTCGGTACTAAGGAATCATGTAAAAATAACTTGAACAATTGGCCGAATAGTTAGAGTATCAGAATGTAAAGGAATTAAAGCCTTATATGTCTGATAACCAGGTAGTCGAAAGCATTCAAGACAAGTATGATTCGTTATTGCCTTACTTGAACGAGAAAACACGGCGTATTTGGGCAGCAATCGAAGCCCGAAGCCTGGGACGGGGAGGTGTCAGTCAAGTTGCGATTGCAACTGGGCTATCGCGTACTACAATTTATGCGGGAATGCGTTTGCTGTCAGAACTTGATGGGGTGAAAACGGAGGACGACAGTACTCGAATCCGTACTAATGGAGGTGGACGAAAACTACTAGAAGAACAAGACGCAATGCTGCTATCAGATTTGGAATCACTAATTGAACCAATGACGTTGGGAGACCCAGAGTCTCCTCTAAAATGGACTTCTAAAAGTGTGGTGAAATTAGCAAGTGCTCTAAATCGTGGGGGACATAGAATTAGTGCTAAAAGTGTTGGCAAAAATATTCATGTGTGTCATTTTCCTCCCGGCACAAGTAAATGGAACAAAATTGAGCATCGTTTATTTTGCCACATTACGACTAACTGGCGAGGTAAACCTTTAACTAGTTTGCAAGTAGTGATTAATCTCATTCGTAATACTACCACTACACATGGATTAGAAGTTGAAGCTCGGTTAGATGAAAATTTCTATCAGACAGGAATTAAAGTCACAGTTCAAGAACTTGATACCATTGCCATTGAGCGAAACTCTTTTCATGGTGAGTGGAACTATATTATCAAACCCCAAATTTCTGCCTAATTGTTCAAGTTATTTTTACATGATGCCTAACTCCGTTCTCTCCAGCAGCCGTTGCAATTTATTGCCAGTTAGCTGCTCTAACGGCTGCTCTAAAAAATATTCATCAAAAATGGATTTACTATCAGTAGACACGTCCACCATCGACAGCGATCGCACTGCATCATAGACCGAGTTAGAATACTGCTGCTGGCCTGAATAACGCCTCTTCACCCACCAGTCACCGTTAGTGCATCCGACTTGCCCCAGTTTCACGCCGTTGTTGTTGTAAATGCCATCATCGAGAATTTCAAAGCCATAATTCTGGCACTCGTTGAAGATATGCGCCATGATTTGGTTTTCGGTCGTAGAAGAGGACAAGGAGCAGGGTGCGGTGTGCAGGGGGGAAATTTCTTCTCCCTTGCTCCCTGCCCCCCTGCTTCTTTTTCCTGCACAGGTAATGAACCGTCTTTGTAGTGAGTGCAGATGAAGCGATCGCAACGCATTAGAGTGTTGGCACGAAATATTTCTTTGTCGTTTACCATGACTACCCAGCGTTGCGTTAAGTGGTTGTCGTCATGGCTGATGCTGGCTATGAGTTGATTACCAGCGTAATATTCGTGATGGTCAAACGAGATTTCGACTATTGTGAGTGGTTCGGGAGCTACGGCTTGGGCTTGGTCAGCGATGTAGTTGTCGAGTTCGGCTTGGGCGAGGGCTTGGTTGTCTGGGGTAAAAGTGGTGAGTTTCTGAATCTTGCTTGACTGATAATCAGCGATCGCAGTAATCCAAGAATCCTTACAGCGTTTGTCACTGACCTCAACTGTGCAGGCGATTTCACTGTAGATTTGCTTGAGTCGGGCAATGGATTTTAGTTGTAGCTGTTGTTGGCTGTAGATTTGGTATGTCATGATTGATTAAGTTCCTAACGGGACGGAAAGCGCTCAAGATTCGCAGTCCGGGCGCTTTCTTTATACTTACTAATGTAAACTGTCTGCATACACTTGTCAAGCGTCTGTAGACAAAGTACAATAAAATTAGTTTTGGAGAACTTATTTATGAACTTAGTGCAAGTAAAACGAGTAGTTGAAACCGTCTTGGACTTTCCAGGATTGGGGCAAAAAATAAGACAAGCAAGGGAGCGTGATGAAAGAACCTTGACTGATATCTGTCGTGACTGTAAGTTAAGCCGTTCTTACTGGTATCAATTGGAAAACGAAGATTTAAGAGCGCCTGCAACAGAGGATGTCATTCGTAGAATTGAACAGGTTTTGAATATAGATTTGGGGGTAAAGTTTGAATGATTGAGCCTTCCACTATTAATCCCCTTGCCCTCCCATCGGTTCCATTAGAGAAGAAATCACAGTTACCCACAACACCTTGTGTTTACTTTGCAATTGATTCTCAGGGCATAGTTCAGTACATTGGTATGACTGAAGATTTAAAACAACGTTGGGTTTCGCATCATCGGTATGAGTACCTAAAACTTTGCAACCAAGTAAAAATCTCATATTTGCAAATTGATGACATTGCCCTGCTGCCAGAAATTGAAGCTGCTTTAATCAGGTACTTTAACCCCCCAATTAACAGAATGGGAAGCAATTGGATCTACTCTGTTGCTAAACCAGCAGGGCTGAAAGTAAGACGGATTATTAAGCTAGAAGTTGATGTTCCTGGATTGGGCGATCGCATTAAACAGGCCAGAGAAGCTAGGGGGCGGCCAGTTACACAGATGGCCAAAGAAGTCGGAATATCTCGTAACTATTGGTATCAGTTAGAGGCGGAAGCTGTATTAGGTGGTGTAGCAGAAGAAACTCTTCGGAAAATTGAAGAGGTGCTGGGTGTAGATTTAGGGGTACAGTTTGATGATTGACCTTTATACTATTAATCCTCTTGCTCTCCCCTCTGTCTTATTAGAGAAGCGATACCTGGGTTGGGCTACGGCTATGCAGTTATCAGTTACATCCGAAATTTACGTTGCAGTTGACTCTGAGAAAATCTCATTGAACTAGAAAGGTGGAATCATGTCTAAACCACCTTCTAATCGCAAAAAGGCCACCTCTGCCGCATCTACCGATTCAACTTCAGCAGCTAACTCTGCAAATGAGGATATCTCCCAGCAAGTAGATCCAGGTTCAGCAACGATTACAGTTACGGCTGTTGAAGTAACAGAGTTGACCCAGGAGGAGCAAAGCGATCGCCTGCACTTGGAGAGGAAAGTGGAACGGGCGTTTTTTGAAGCGGGGAAAGCGCTGACAGAATTGAGGGACAGACGGCTTTATCGCTCCACGCATAAAACATTTGAAGATTATTGCCGCGATCGCTTTGGGCATAGTCGTCGGCAATCTTATCTTTTAATGGATGCGGCGGTTGTTTTCGATAATTTGATGGAAAAATGTGATCCAATGGATCACATTTTGCCAACTAACGAACGTCAAGTCAGACCAATGACAAAGCTTGAACCCCACCAACAGCAAGAAGTGTGGGTAAAAGCAGTGGAGCAGTCAGGGGGTAAAGTGCCACCAGCTAGAATCGTTAAAAACGTAGTGCAGCAAATAATGGAACGCACCCAAGTACCGAACACCTACCAACTTGGTGAAGTCTGCCAAATCCTTGTTAAAGACAATCCCGAACTGAGAGGCAAAGGTGGGTGTTGGGGGATTGTCAGCGCAGTGAATAATTTCAGTTGCACTGTCAAAACCTGGGATGGGGAGTATGCCGTTGCTTTGCAGCACCTCAAATCTTACAATTACCTGCCTGTGGAGTGTCAGCAGATGCAGGTTATTTGCGATCGCATTAATCAGGTGTATTCGAGTGAGCTGGAGGAGTCGGTGCAGAAGTTTTTGGAGTCGTTGGGGAGGCTGAAGCGGGCTTATTTGACGGCTTTAGAAGAGAAATTGTTGAGTTTGCTAGAAGCTGAAATTGCAAATTAACGTTTGTTAAATAATGTTTGACTGTCCTCCTCGTTACTTCCGGTTGAAATAGGCTATTTATGTAATGCTAAGGGGATTTACCAAGATGCCAAAAAAGAGCCAGAGCAATTCTTTGAGTAAGATTAAACAAGAAACCTCTGTTGGTTCGCGCATCTTTGAAGCACTTACAGAAGGGGAAATTTCCCAGCTACTGGATGAATTATTTGCGGTTTTATCCGACGAACAGCGAGTAACTGTGTTTGCTCAACTGCAAGGGAATACCCAAGAGACTTTAACTCAAATCATCGCTCCACCTCAAACAGTAGAACAGGTAAAAACAAGCAAAGTACAACCAACTTCTTTGGCAAAATTAGCTCAAACTTGGTCCCAATTATGGGGAGAGTGGAATCAGATTATTTTGTCAGCATCCCAGTCAGAAGGGAAATATATAGTCCAAGAAGCAAGCTGGGAAGAACCTTATTTTGATGACTGTACTTTTGTTGAAGATTTAGAAGCTGTTGCACAAAAGATGAAGCCATTGGTAAAAACGGCTTTTGAGAATGGCTTTAGTAATGACAATGGTTTTGCAGCCAGTTTGTTGTCAGCAGAAAGTGAAATCTCTAATGGTATACCCGACTGGATGGAAATTGCTAATGGTATTCATTTGGAAGGAGCGACAACAAGTAGCTTATTGGAATGGGAATGGTTATTGGTGCAGTCACAAGGACAAAATGGGTTCAAATTAGCTCAAAAAATTAGGGAATTGGATGAAGAATTTTACCACACCAGTTTAGATGATGATGCTGTGACCGATTTCTTTTCCCATTTACCTGATGTTGAAAAAAAGTTAATTTTTGACGGATTGACTGCCAATCGAGAAGTTTCTCTGTGGAAGCATGACTTAGAGAATACTTTTTCTTATTGGCATATAGTTTACATGGAATTGATGCAGCAATTTGCAACCCCAGAGATATATTTGAACAATCTCCGGGCGACTATTTCCCAGGAATGGCAAAGTGGTTTACCTGTAATTGAGGATTTGTTGGCTAAACAAGAATATAGAGAAAGTCTTACAGTGATTCAAGAGACTTTGGATGCGTTATTAAAAAACAAACATGACTTGAATCCCTGGACACCAGAAAACTCGCTGCTATTTGTTGCTGTGGGTGGATTTTCTTACGCTCCTGGGAATTGGGAAAAGGAAAAAACTTTACTTCGCTATTATCAGCAAGCTGTTCGAGAATTGGGAGAAATCGAACGGGTGAATGCTTTGTCAATTCAGTATATTACTTTTGAATGTTGTTACGACTGGTCGAGTATGTTCAAAGCTTTTGCTGAGATAGCAGTTAATAAAGAGACTCAGCAAGCCTTGTTTACATCTTGGCGTGAATCGATAATAAAACGTGGTACACCATACAGATACTCAGGTTTATATGCACATCAAAAACCCGTAGATACTTGGTGGTTGCATTGGTTGCTCGATAGTATTACAACTAAGGAAAAAGGACATACTTGGTTTAGGCAACAAATTATCGAATGGTTGGAGAATTTACCTAGAGAACAGGGACAACTGGGTGGAGAATATAGTCAGGACTTACGCAACTGGCACAGTGCGATCGCAATTTTATAGTATTTACGTACTATGTCAAAGTGGCGTACCTAGAGGACATTGCTGAAATTAATAACAGTAATTAGCTGTGTTAAGTATTTTTCAAATCATGAGAAAATGAGTTGAGTATTCAGAAAATAAATCTTGTAGTTTATGAGATTTACAAAACTTAACTATTGCCAGTACTTGTTAAGTAGTCAGATTAATTATACTCTGACAAATTTGGCAGAGCATTTAGAGCAGATTAGTCATGATAAAATTAACCGTTATCTTAAGAATGAAAAGTTAACACCACGTTTACTTTGGGATAATGTTAAAGATATCTTACAAGTGAGTGATAGCGCATATCTAGTTTTTGATGACACAGTACTTGATAAACGATACGCCACAGAAATAGAGACCAGTAAAAGGCAGTATAGTGGCAACCAACATGGTGTAATCCAAGGTATTGGGCTAATAAATTGTATATATGTCAATCATGAAATCGGAAAGTTTTGGATAGTTGATTATCGGATTTATGACCCAGATAGAGATGGAAAAACAAAGATAGATCATGTTACAGAGATGCTGCAAAACCTTATATATCATAAGGCTTTACCGTTCCAAGCTGTCTTAATGGATACTTGGTATGCAACAAATAAATTGATGTTATATATTGATGGATTAGGAAAATATTATTATTGTCCTCTGAAACGTAATAGACTTGTTGATGATACGGCAGGTCAAAAAAATTATCAAAGAATTGAATTGTTATCTTGGGATAGCCAGGAGTTAAAATCAGGTAAAATAATTAAAATAAAAAAGTTTCCCCAAGCTACAAAAGTGAATCTCTTCCGGGTAACTGTCTCGACCGACAGAACGGATTTTATCGCTACTAACGATTTATCTCAAGATTCTACGGACGTTGTACAAAAAGTGTGTAAGGTTCGATGGAAGGTTGAGGAGTTTCATAGAGAATTAAAACAAGTAACTGGTATTGAATCGTGTCAATGTCGCAAGGGACGTATTCAAAGAAACCATATTGCCTGTGCTATTTTAGTCTGGCTTCGACTCAAACATTTAGCTTATCAAAGCTACCAAACAATTTATCAAATTAAACATGGATTATTATCCAATTATTTAGTTCAGCAACTAAAACGCCCGAATGTTCCCATGTTTATTGTCTAGTTGTTTGGCGCTCGGTGCGGCGCAGCCGCACCGTCGTTTGTGACAGTTGCGTAAGTCCTGATAGTGTTTTACATTTGTTAACAAGAGATTTGACCGAGATAAAGTATCAGGGAAAATCCCCCTACCCTAAGTTTTATGAGGTTGTGATTCTACCAAACCAACTATCGACACGGGATGATATTTCTAGGAGAACGTATCTCCAAGAATATGCACCCCCTGACTTGTGGGAAAGAGTGATGGCTTATTGGCAAGCAAATTTACACAACTTTGTACCCAGACCGGACTCGTCTCAAAGCTCGGATTATACGAAAAATGCAGAATGGATGTCTGCCTTGAAGGAGTTAGCACCGCAGAATTATGATAGTTTGTTGTCCCAATGGAAAGTTCAGCATAAGCGACGACCTAATTTGTGGAAAGCAATGAGAAATTTGGGATTGGATTGATGTAATGCTTTTTGTATGTGGCATGGGGAGTACACAATTAGGTTGCAGCACATGAAGTTTTTCAACGACCTACCCCAGGAGTGTCAGCAGGTTCTGGAGATTAGCAATCGCCTTCCTTGCTCAAATATATTCCGATTCACTCTTTGGAGACTGTCAAAAGTCTGTTGCAGTCGTTGGGGAAGGTGAATCGTCCTTATCTAACTAAGTTGGAAGAAAAACTTTTGAGCCTTCTAGAGTCTGAAGTTAAAGTGTAATAAGCTGTTACGCAGCTTGATTGTATAATAAAGCTAAGTAATTAACCTAGCATTAGCCACCTATGCCAGCAAAAAACCATCTTTCTAAAGAGCAAAAGGAACGGTTACTAAAAACTCTAAAAGAGCATGAAAATCCATACGTAAGAGAAAAAATATTGATTTTATTATTAATGAATGATGGAAAAACTTATCAGGAAATTAGTAAGTTTTTAGACATTGCATATCCAACGGTAGCATATTGGGCAGTTCACGGCGATCCAGATAACCTAGAAAGTTTTTTAGATGGAAGAAGAGAAGGTAACTTCCGCAAAGTTACTAAAGAATATGAGGATTTATTATTAGAAACAATTGAAAAAGAACCACTAGATTATGGGTATGATTTTGGTCGTTGGACGGCAGCAAGACTAGCCACGTACCTCGAAAAGATAACAGGAATTAAGTTAAGTGGTTCGCAAGTTGGGAGAATATTAGAGCGAAAAAAGTACGTTTACCTTTGGGCAAAATACAGCCTAGAGGACAAACAGAATCCTGAAATACGTAAGGCATTTAAAGAAAAATTGTCAGAATACTTAAGAATAACAAATGTTGCCCCAGAGCGTTTACAGGTATGGTTTTGGGATGAGAGTGGATTTAGTTTGAGAGTGATAAGAAGAAAAAATTGGGGTAAGAAAGGTACAAGAAAACAAATCACAGGTCAAAGAAGAAGAGGAAGAGTAAATATTATGGGAGGGTTACGCTATCACGACAAGAAGAGAATGAATTTTGTGATTAAAAAAGGAAATGCAGATGTATTTTATGAGCAGCTTAAATCTTTGAATAATTTTCTTTTGCAAGAATGGATAGAGCAAGGAAATCCAATTGAGACTTTCAATAAATGTTCGGCGAAAATAGTGATTATCTTAGATAATGCCAGCTTCCATAAAAGAAAAGATATTTTAGTTCGTATCAAGGCAGAAATGCCAAATATTATCCTGGAATTTCTACCACCTTATAGTCCAGATTATAATTTAATTGAATTGGTTTGGCATTCAGCAAAAGAATATATAGCTCATAGATTGTTCGAGTCAGTATCACAGCTAGAAGAGTTGTTAAATAAATTGTTAAATGAAGGAGGTCTTATTATTAAATGGGAACGCAAAATTAAAAATAAAGGTAATGCTATTTATTAA

Protein sequences of DBSCAN-SWA_2

>NZ_CP046705|112551:178095|150220_150823_+|WP_109012817.1|DBSCAN-SWA
MAGKRPRQGWIYSTNPYRVSLRCKLGHIHIYNLDEPAEVECQTCSENINSSRVFRGTHPYIIWTSDQFQDESGYIATFSVIPLTSQTTFNGLPTTYPINSTSRNGLDKNSYALVHQICTVDANCFKGSSANWLERIGQLDKADREAIEERLKYFLSIQENPSEDWFAQNASPELLKKIFDYLPEDTKNLVIEELINNLDS
>NZ_CP046705|112551:178095|151799_152759_-|WP_114086241.1|DBSCAN-SWA
MSNIHTLQKIFPAGFDNGYGSLKLLVDGFEVVRVPSYITNAEMEDVPGRVVFNGSAYTVGESAFRTGNYFDRNTDNNENKVNNALLTLFGALAHLPHRKAWHLKLVVSLHDVALAEELQKVLNGEYQPILAGKQSEVKIEVLKVVLEGMGALFGHQLPKKLTILDFGNGTTLYSRYNQGKREVHTAYPTGVEVLINDISQKMKHLNGGKIGDASKIRFCLEMGHTRYSRDIDIKDVYSACLKDWYEKYLKKVVNLTLDAKHQGDEIWAIGGGCLLPGFKKLLEKNGFKILDNPVEANVFGLLEMAKAISSKNSPTTSIK
>NZ_CP046705|112551:178095|143550_144054_-|WP_114086249.1|DBSCAN-SWA
MHKKEFHPDGSLKNEARQEMLSVGMSNEAIDDYASRLKARYDEWKHLDETDPEPWPIYTAYDFFTEQEKKEFNPDGSLRPEYVEYARQIGISESALEQLEWRKKIEVDDYNEMSANHVEQGINFGEWLMQGRIGNSRTYVQRRQQMEQDLHNFEDVDSLPFDKDTSY
>NZ_CP046705|112551:178095|165631_165925_+|WP_147262459.1|DBSCAN-SWA
MEQEVLRVILLGAAIADAKKIMERNWFKCEIYENSTFIRYRKIPGNSESETKLFSHVDFILCTRKKGFIVKQNWIVGIIYEKERVTTVVVNYGLTGS
>NZ_CP046705|112551:178095|171599_171845_+|WP_114081105.1|DBSCAN-SWA
MNLVQVKRVVETVLDFPGLGQKIRQARERDERTLTDICRDCKLSRSYWYQLENEDLRAPATEDVIRRIEQVLNIDLGVKFE
>NZ_CP046705|112551:178095|116707_117100_-|WP_114085048.1|DBSCAN-SWA
MSNTDANFQKLFQSKNQVNKDNENPKLLVNRLTPTDDQIKDWLQSPQIKQWLTKLLMGIPNNLKIEAINTIIKNVIQNPDKDSRVQFGSSTIGVDVLRWQLWASYKLPYASGIKTPDCPYTLKNHLDASD
>NZ_CP046705|112551:178095|123809_124529_+|WP_114085040.1|DBSCAN-SWA
MKLLERKELNFTPIFLIVNAILLTLLLFIEIVNFARIATFSKTKASTLVELSDGESIRVIPIGSLERSPQAITYFVGQTMTGLLSWNALPKPSDDYKIDPTKQLKLDPGISTSKAKITTSAWASGFALSEDFRAPFLEEISNLTPPDVFNGSTQSILKVSLISQPTRIKDGQWKVDMVAEIVVFQGSNLVGKPMAFNKTVFVRAIDTAALPRFASDVQETASRVRKAGLEIYKIQDLDL
>NZ_CP046705|112551:178095|118776_121515_+|WP_114085044.1|DBSCAN-SWA
MVKSSIRNQKIVPFEDFLDLATLVKLKKGSYQIGAYLLSKKQVSDTNNTLQLVFGYECTGFHPLFNSSERLEAIAKAFENGCKEFSEGEKFTFRWSSFCDEDKVIEDYRQRLASPVSLESEFLDWGQVARMQELTRNHQRKDIKLSIYTTFTVRPGGTEGGDAVDRAIVKLANFLQRKFTPTGATELTLQNLIQVLEKAIIVSLRHQQILSEMGLFPSPKSDKQLWGDLVDRMGAKAVKVPHTLVYDTGELREEINEATPNPSRYNDQLHATSVLLNNGIPHADRRWVCLPYQSTDKKKYIGVMTLAQKPEVFASTYQQIRFLWDVFSREVIYDVEIITEINPADQKMIRLTQQLITRRSINASASASKKTIDVGAQINTERSVDAQKQLYTGDVPENVAVIILVYRNSPEEIDDACRLISGYINQPAELIREMQYTWSIWLDTLLLRQRPQLTFPFNRRATFFASEVIGLTPVVQTAHGDKQGFELVADEGQSSVYIDLSKPKNMMVIGTTGSGKSVIIASIIYQCLALGMSVLMIDLPNDDGSGTFGDFTPYFNGFYFDISKESNNLVQPLDLSKIPESQWEERTKAHRNDINLIVLQLVLGTQKFDGLLSQTIESVIPLGTKAFYEDADIKERFELARKAGINTPEWANTPTLADMEKFFSLAYIYLGYQDDNVEKALNYIRLRLQYWQASSIGSAICKPSTFQADSQLITFALTNLQSGKDAEVFGMSAYIAASRQSLSSPNSVFFMDEASVLLGFSALSRLAGRKCATARKQGCRVFLAAQDVISIAKSEAGEQILQNMPLRLIGRIVPGAANSFSELLGIPREIIDKNESFVPNIQQLYTLWLLDYNNKYVRCRYYPSYPLLALVANSREEQATRDKFKKIHSDKFTWVAEFSKYYVECIKQGKPL
>NZ_CP046705|112551:178095|122031_122724_+|WP_114085042.1|DBSCAN-SWA
MILTSFSSLPATAQTNQNQSFLTQFQQIYSSLQTYISNYQKEFTKSLGKLEAELTQAIESSVGDLGIPDPLKAGKNIEKVIQKQEGALLILDPRIQAGNAIKEWNQQYTRGQSESVLGVEGQRVQSQEAAITNDATAQSSENAAAAQEDVITQDILKKVAIQNLQNVVIAKSIHSEAQKQSRSLAVANINLADISNRLDEQAAAKDQESNAATRQIIQSAAANDSFWKNQ
>NZ_CP046705|112551:178095|149212_149473_+|WP_109012819.1|DBSCAN-SWA
MHELIACGFYKKTTPNGKKVFDKNALALAPLKEVRHKLSLLSEYPNRAARFKVPALWVDAWCQRCFVSFTEMVKWRRVIQRDATSP
>NZ_CP046705|112551:178095|130656_131157_+|WP_114081708.1|DBSCAN-SWA
MSRPFEIEIAESEEELKKRLQTANLGNQKEKLIMLWWIKSGQAKEQQDIGKRLAKDTSTVTRWLQKYRSGGLDELLKIKKAPGAKRKIPEGAITALEEELKTGKGFSSYGAIVEWLKQEQGLDIEYATVYALVRYRLGAKLKVPRPQSHKQDEKLVSEFKKNSVSF
>NZ_CP046705|112551:178095|118444_118783_+|WP_114085045.1|DBSCAN-SWA
MSEYNKSPMKRVNQSLGQNATISIFTGFQFAVALFMFGVGFIIAIMFGAGIVWGLLAGVWLSATVIVLSGKRPYLFWSRVFPSVPVFTRGYVRYSSPQNKKRAGSKGMPKLW
>NZ_CP046705|112551:178095|158186_160145_+|WP_159402649.1|DBSCAN-SWA
MSTPPNLSPQQVSAFPQHETITGVVERLTFYSAESGYTVARLTRPRSNELTTIVGSFANIQPGQTLQLIGFWRDHPQFGPQFQVINYQETKPATLTGIEKYLGSGLIKGVGPVTAKRIVAHFGLETLDIIENQIERLIEVQGIAKKRITLIKNAWSTQKAIKEVMVFLQGHGVSTTYAVKIYKQYKDEAIATVTKNPYQLAADIYGIGFLTADKIARNIGIAPDSEFRDRAGIVHCLSEAAEDGHCYLPQSELIDSVIKLLTTESHQSTEEAVAIIIKDMALAEELIREWDEEKRLLCYKPTYFHTEQNLAQLIRQRLENPVGTDIERVRDWIDRFTASRKIQLSQQQRQAVETAAYSKIMILTGGPGVGKTFTTHTIVTVGPGQILADLINSGCVPVVRLTQVFRQAQTSAIITAAHQINRGQYPTIEPISDNPVSDCIWHGGGHQPEHGVQAICELITDLLPRLGFNPATDVQVLCPMTRGVVGTRNLNTVLQQLINPPSPSKVEINRGGNLLREGDRIIQLTNDYNREVFNGDLGIILTIDTVEQEVTVQYGERTVVYDYADLNEIALAWSISIHKSQGSEYPVIVLLIYMQHYMMLTRNLFYTGITRAKKLAIVVGAKKAISLAVRSTDDQRRYTRLQQRLLHPGLHW
>NZ_CP046705|112551:178095|117971_118442_+|WP_114085046.1|DBSCAN-SWA
MKKGVIALASNNSVRRTQTQVLAKALAAIGRKYQHQIYAAGTATIIVMQSMPSYGWGLFDSAQVAMTCMFGGAGGIGGGGAAAATTAIKALPAVINATITVLLFVYFVASGLKVANGIGEGQEVTQMVQQPVGVFFIILVLWIAQSILFNGVTAAC
>NZ_CP046705|112551:178095|112551_113481_-|WP_114085050.1|integrase|DBSCAN-SWA
MTLSLVHITAHRKAIASLPVAQAEAKLIALWLEGKAESSIISYRRYIRRFLEFLDKPLKKVTYEDLVEYASCFGGNAESTKRIYIAAAKSLISFGHKIGYLPFNVGMALKLGELPDVINERYLDEADIKLLVRAASKHLTDAKTPKRQYTAKRNLLIIKLLYQAGLRASEICDLTWGDLTPRGESGQVYVRKAKGSKNRTILIKPKLWAELMEFKASAHSNQAVFPSQKGGHLDRQNLHPIVKAIAQEAGLSELVSAHWLRHAHGSHAIERGTNPVLVKETLGHANLAITDRYLKARPNDSSALNLMDL
>NZ_CP046705|112551:178095|141343_141778_+|WP_114086246.1|DBSCAN-SWA
MFSDVEFRLRSRVKADSSEAVVIKYLNSKNTLYPARDMAMIAISSYWLPLAYQAMDQSVDLEQHIRACLYRLQLHSSYLMGLLGEIPSQGTPMIAVASNQSQPLQLIQSEPLAISRTLVKEALQIARTPVPEELESETDWLNPF
>NZ_CP046705|112551:178095|131147_131717_+|WP_114081709.1|transposase|DBSCAN-SWA
MILNCLEKHLAPGKCVRYLCQDETRVGLKTLTGKVITASGVKPTVEVKWPRENFWIYGAIEPLTGDHFLYEYPKLNGECFQQFLDWLSQQLGGDYAILQVDQAPAHTSSAIRWPENIIPLFQPPSAPELNPIERLWQLLKKPLKNQLFSSLQNLRDRIQEIFNQLTLEQVISISSYNFILEALFYAASY
>NZ_CP046705|112551:178095|122754_123813_+|WP_114085041.1|DBSCAN-SWA
MITFLVILFAQTTGQKAGEDTGTTNSGEIVEGAISGADLIYKSFENDWLELASGTSPIYTAVVAVSTLAAVVMIGFASFGWYRKYAEEGFGFDFISEMVLPLVVIVMLSNNGFLLANTTVALKNVSTGLNRSILNITRNGVNLRDAIRNVNADQSFVLAAQIALAKCEKLNNEKKEGEELSEKQACIKQAVENTRKDAQKAREKTGAGSGVGSWNPLDLSGELINSAIQGFVYVILSGLSAAFQYIVQLSFLMIAFAAPIFLVVSLLPFQSKPIYAWLAGWLGLTLVLISYSITVGIIASAIVSKPSSNPLLLQLLQAIFSPLLAVAIGTGGGMAVFSAFTSGVKFSVGLRR
>NZ_CP046705|112551:178095|162414_162921_-|WP_114080956.1|DBSCAN-SWA
MTISMYQALIPVSIRTLNNLINILEKGAAYAETKKIDPSVLINSRLSPDMFPLSKQVQIASDIANRGAARLAGIEPPKFEDNETTFGQLIDRIQKTISHLNTFKPEQIDGSEEREITLQMRDNTLCFQGMPFLLYFVLPNLYFHVTTAYDILRHCGVELGKGDFLGQP
>NZ_CP046705|112551:178095|153870_154971_-|WP_114086240.1|DBSCAN-SWA
MRVSVLNPDGSPAMPTKPSRARRWLKAGKAKVVHNDLNLFCVQLICEPSGYEVQDIALGIDPGKMFTGIGVQSSRFTLFTAHLILPLQAITKKMNGRRILRRARRARRINRKVAFHLRAHRQKRFSNRRQGKLPPSIRANRQMELRVTKELIKHFPVSDIRYEVVKARTEKGKGRGFSPVMVGQKFMFQWLEELCPTVSQEGWQTSTLRRQLGLAKDKGDKSKQIPETHANDGIALAASHFMSYQSFQSSNGRGHHWQGQVTVTKSVFRVISRPNLYRRQLHFENPVSGVTGNRKRKGGTITPFGFRSGDLVRAKKSGKTVLGWIGGYSEATKVVSVYDINWRRYGQFKASKVELLQRSTRLCVSR
>NZ_CP046705|112551:178095|161823_162324_-|WP_114081708.1|DBSCAN-SWA
MSRPFEIEIAESEEELKKRLQTANLGNQKEKLIMLWWIKSGQAKEQQDIGKRLAKDTSTVTRWLQKYRSGGLDELLKIKKAPGAKRKIPEGAITALEEELKTGKGFSSYGAIVEWLKQEQGLDIEYATVYALVRYRLGAKLKVPRPQSHKQDEKLVSEFKKNSVSF
>NZ_CP046705|112551:178095|125979_126810_+|WP_114085038.1|DBSCAN-SWA
MLKKTTIIAAFLILTSAAKATAITARTVYQNDANSNAIELKVWKGYGLTINLMSTGETIKQVWIGDPSRFAFTSNGALCQSSGNDSDCTGGKATVIFLRQIDPINFPVTSSSNGSTQITVLTNDNLYQFKIVPATGNPAYTSLVIKSDSERPLPITRPRTPQPLTVEKPQSAPPDFPQPSPPPQTITVQKPQPVAVLRPNPGTTLNGAIQRNDANALAFGLAEAGRKGQVKPGSTTWNKVQDAIKLLRRGKTRDEAISLSQVDKTIFNQLLQWGQL
>NZ_CP046705|112551:178095|165921_166215_-|WP_147262458.1|DBSCAN-SWA
MLSKFVEGMLSHPWQLKIHSVHQNFLRYLRCSRRIAQAQKWAIPYYIPVGKGASRWMKAAGIAIDEEHFRKFGARVFLSKQGKVLSSPKWVSRWLPH
>NZ_CP046705|112551:178095|127335_128529_+|WP_114085037.1|DBSCAN-SWA
MKLKPFLLAAIASLVPLSASVAQTPTINYSQGKYKTAAPDWSKITWDTLPPVQQPGFLKIPKNLISTFGYDPSRSWTAGQKVDSVVMLGDADDAFKMSDLSLKAIDTVALSTTATTTKPTLKDFGLMQWQTPKTLVKAMPELSNLSLSEVPPLADLFSKNGAGLGSSTISQAIASNPQVANLTLDKIDLSKYSLDSIPGLDKTQLGKFKSWQQAYVNQIPKLSQVPFDKMPQPISSGIGVVGIASVVLGTAEKGDRRAGNDYFVSGSVVRGDRTLTVACPPGIECSYLEIGDFAGSQGGLYGKRWASGSSQQVKGGYGFLAAVNGGKEPTGRLVYGSGFKVALTGVNESLGTADFGLFFRICARPPFQQKTCTPYFIGPVPWLPVSENDLVIVGTGR
>NZ_CP046705|112551:178095|169836_170565_+|WP_114081802.1|DBSCAN-SWA
MSDNQVVESIQDKYDSLLPYLNEKTRRIWAAIEARSLGRGGVSQVAIATGLSRTTIYAGMRLLSELDGVKTEDDSTRIRTNGGGRKLLEEQDAMLLSDLESLIEPMTLGDPESPLKWTSKSVVKLASALNRGGHRISAKSVGKNIHVCHFPPGTSKWNKIEHRLFCHITTNWRGKPLTSLQVVINLIRNTTTTHGLEVEARLDENFYQTGIKVTVQELDTIAIERNSFHGEWNYIIKPQISA
>NZ_CP046705|112551:178095|175215_176229_+|WP_159402562.1|transposase|DBSCAN-SWA
MRFTKLNYCQYLLSSQINYTLTNLAEHLEQISHDKINRYLKNEKLTPRLLWDNVKDILQVSDSAYLVFDDTVLDKRYATEIETSKRQYSGNQHGVIQGIGLINCIYVNHEIGKFWIVDYRIYDPDRDGKTKIDHVTEMLQNLIYHKALPFQAVLMDTWYATNKLMLYIDGLGKYYYCPLKRNRLVDDTAGQKNYQRIELLSWDSQELKSGKIIKIKKFPQATKVNLFRVTVSTDRTDFIATNDLSQDSTDVVQKVCKVRWKVEEFHRELKQVTGIESCQCRKGRIQRNHIACAILVWLRLKHLAYQSYQTIYQIKHGLLSNYLVQQLKRPNVPMFIV
>NZ_CP046705|112551:178095|155276_155543_+|WP_159402647.1|DBSCAN-SWA
MSAVASYCSTVVVLQLVSVSAVSAVIIEGKNFICIINRKYLSPITLEEGVCHHSCQGKGIAVVESTSLACSLIAVCSQLGHFTFVKIT
>NZ_CP046705|112551:178095|166224_166803_+|WP_114080952.1|DBSCAN-SWA
MNQVRLPKVSVAVIGLVVASVFHATPVLGAILTRQEFSGDFTLVDATSPFLTNSLPFKSEYSGFVVYSESGTLSDWELSVNNLDLNLKRGSTNGGNLTPDVDFEFGSGSNWNLVVDFGIAFDAPRYTLEKTSSSEISLTGEVGRAGTYIYQDSAANITLSSSSTSVPEPASLLGLLFGVGAIAVSKKASETK
>NZ_CP046705|112551:178095|121511_122054_+|WP_114085043.1|DBSCAN-SWA
MKVLSSVIENKLLLAILAGVVSIVGFQVWQYNQAQYEKLISEAKNGCGVYIELGEDAIKRSPSLRALKYQNKRLSGLEQPGINSESADPGAYIMLFRSPASTLPPNALPFDDTFFTSLLNKEESPKTLMVQAVSFDLAKKQATVKSLCTKKPFVVALEDLYLEYQPIDRNLRRSDFDILF
>NZ_CP046705|112551:178095|117602_117914_+|WP_114085047.1|DBSCAN-SWA
MGIGGFTWQNEELTRPEVAAMLKPKVSARQLQAYLNIARKYLPEFQKFTNKKTGGLDGYAKLYECHITVLQEIRSLAREHTLADIESEFQQRALNKSEVGSGK
>NZ_CP046705|112551:178095|141904_142711_+|WP_114086245.1|DBSCAN-SWA
MYQPQELFNELSTSEISRTLRLSGISEKELYTEDDADRFRECRTLIEQGGTDEDVMALLSPVVDVVLSETPDNSLAEIKNGRKKSGKKATKSLDITELLSLAREQGFKLTLTTALKIFADCGLKEQDEYTSEESERFLAACNLRHQGKTEIEIAANFGAGVLDAADIELSLEETERLIQDSGDLLFGEMLREKAGQHAAIAPGLYLKYLAQELASESSQQNWRSLLEMIKARAVGKPQPQFTLKVQTLQLQQPLNSLPPNSENGSTSD
>NZ_CP046705|112551:178095|156886_158005_+|WP_114086237.1|DBSCAN-SWA
MALPKIASRFSSAVQKTEQEQKIAELQIEIERLRTAQSPELENELQKLREQLQNQSGEVQVDLNLIDPNPNQPRQTITPELIQAKARLLKKHGQISAVILVRQSNGRYILLDGQLRTEGAKLLGWSTIRAVIVAMPNDLDQSALLTFLGFEDLNPLDKAEAVFKEVMKSANLSMDEVSTMLGTVIKRIERNGNSKELAKLMAVSVDEQQQGLELLEITGKEQSLLLVLLELGLNPSSVKANLMPMLYLPEDLKQVIRQHGLKGAHALALATLSAKALDISENQAASERIAATDEVLKKNLTVTETRELVRKIKIKYLKSNEQELKEVKIIFQKVNGISGDLLKKASSKQLHEMRSLFQEKLQEIDKVIATSK
>NZ_CP046705|112551:178095|114111_116238_-|WP_114085049.1|DBSCAN-SWA
MPAPLKVDLSPIEDQALLALTQAKGIPPRTQSRATVLRLSAAGWTVLKIAQYLKWHPQTVRDTIHRWYWGKLDSLWDCSRPGRRRRWHNPNIKSLLQFKISLFSYQLIFILFSYISYIYLMLFFHSHGVSTTYAVKIYRHYLDEALATLTSNPYQLAADIYGIGFLRTDKIAFNLGVAPDSQFRYRAGLIHVLNEAAADGHCYLPQSLLIENVIKLLTTADHTPEEDALADIIKDMALKDDLIREKSEDQTLLCYLPTYFHTEQNLAQLIQSRFCQPVAQDMPRVRAWIERFTKSHKIKLSPQQRLAVEMAAYSRVMILTGGPGCGKTFTTHTIVSLWKAMGKSIALAAPTGRAAQRLSEITQLEAKTIHCLLEFDPKTMGFLRDNQNPLPHTAIVALEASMLDLFLASSLVKAIQYGSQLLLVGDVDQLPSVGPGQFLADLINSGHVPVVRLTKVFRQAQQSAIITAAHQINRSQFPTIEPISDNPVSECLWHGGGHHPKHGVKAISGIITDLIPRLGYNLATDVQVLCPMSRGLLGTRNLNTVLQQLINPPSPDKVEITRGGNLLREGDRIIQLTNDYNHEIFNGDFGIIKAIDLEEMEVTVQYRKHTVVRTRADLNQIALAWSLTIHQSQVSEYPVVILPIYTQPYMMLSRKQLYTALTCAKQLAIVVGSKKAISKALRSSDGQLRYTRLQQRLESAFLHPTIAI
>NZ_CP046705|112551:178095|128525_130289_+|WP_114085036.1|DBSCAN-SWA
MTGTPKTIVKPNQFIPPGLESALFSPAGLGVLACGAVIVIAKIIDSRGGIAKLATARWGGAVEKKAARQLACKQIQLRLHNRVSLYVGTPKNTTSEVINGIRKTSIPEDSTTLYFPEAQRGILVCGGPGSGKSFSMINPMIRSAIDQGFPLVLYDFKYSEQESATSTSKGQAPILAGYAALRGYEVTVLAPGFAESAVANPIDFLRNNEDSEMARQLAITLNRNFQLGEKNSGNNFFTNAGDQLVQAVFMLAKGTEYPDIMMCQAILGLPKLVKRIEQAENLNFMVREAFAQFVSVAGSPETAASIVGTASGLFSRFMVPSALAAFCGKTNIPLDLKGRQMVVFGMNKEKRDVIAPLLVSILHLLVSRNVANKRTCPLVLGIDELPTLYLPALVDWLNQNREDGLVSILGLQNLSMLIESYGENTTNAIFGGCATKAFFNPQDDVAAERFSKFLGEEEIKYKQRSRSSGGKGGASISNSDQNSTRKLFDVNQFNTLPSGKAVIISPGFRSRGQISLPILQSIKIPQHEIQSETDSVKAWYEFQKFLSKKSTLLTPADEEMRIRRAEALKLLPLIENQEQLSEYASLI
>NZ_CP046705|112551:178095|176988_178095_+|WP_159402646.1|transposase|DBSCAN-SWA
MPAKNHLSKEQKERLLKTLKEHENPYVREKILILLLMNDGKTYQEISKFLDIAYPTVAYWAVHGDPDNLESFLDGRREGNFRKVTKEYEDLLLETIEKEPLDYGYDFGRWTAARLATYLEKITGIKLSGSQVGRILERKKYVYLWAKYSLEDKQNPEIRKAFKEKLSEYLRITNVAPERLQVWFWDESGFSLRVIRRKNWGKKGTRKQITGQRRRGRVNIMGGLRYHDKKRMNFVIKKGNADVFYEQLKSLNNFLLQEWIEQGNPIETFNKCSAKIVIILDNASFHKRKDILVRIKAEMPNIILEFLPPYSPDYNLIELVWHSAKEYIAHRLFESVSQLEELLNKLLNEGGLIIKWERKIKNKGNAIY
>NZ_CP046705|112551:178095|144128_148916_+|WP_114086243.1|DBSCAN-SWA
MTLELKHFDPRLNQWIYTDDNKTNSQSILTEKLNNTLLEFYFPDKEFSFGHSDEYSTAEELKNHPNGQILLLSSKTRLLYGDKECLEVIQKICPDSKDRGAYGSIFLGACKNAIHEKLNILVVDDSTEKAGENGGILSNDLAYKLVGDCYGQISTQLYDKVTLRESQPDKSYRVIQHRFGWVDGVGEDTTKYRFGKGTLRPYRLDEIKYADPNNKPKIDIILPVSSFKGTDKDRPKGPTKPQIQPGLYQQNIWLAEKGQSQQGQMSISQLLASFPQGIKDFAEELEVQAQRLASIQDNPRNVAAYYCERYEKRKESLSQNKLKTSDIINQETDVKNLGTNDDLDADHELDDESAKDDLFMYKLIKADLLGHQQLLETEKVKQELSRFVQSEWRDIAVGKTLTFDRGMIIPSKELKNGEICVPWLKLGEKVLNFRSPFLNSNGLCVSTNKHVEDSVAPDGKSLQGIIVVNDEDHKRILARIEALETQGIEHNEVNPLETESERQARDYDGDCIGVAKASLYPNLTAEAERRNLPQNAYSPTVKLKKQSFYLEDGSQPPFEKIAIHMSDSISVGIINNQVTALEALESEIEVLKTYGTFEQKSNYLDQVSNHYETLFEQERQKDPKLIREEYKPYMQGVVEIAHCQRTPEIIQQAMDINRQMYRSMIEEGCYQNQIAVDLFKSAKKPEMNLIRENNRYLYRDVNYIKDKKSSSVYLSTGITPKGYSPVELLINQTNKYFQESQLESRPIVQFKDLFKGVEFTPQQKFAAIAAKYEFDQKFNAAVRASRRRETESGPSAIVQTDSGTQLEITNLTRYGHPLIWKAQTLSIHLDEIKFTNSERPHKLLAVAQIDGEIGEDGKPAYRNLGTVSQQSQADYNLKAGMTIQGAKLLELKPELTRSQTKLLFALAQETAEAFYAKIPESEKLTGAAAAWNICASRQDELEVARKENANPQAIAKKVSNFAFAAFPNEIISRLDKLQFTEPKLVTLNNEANQFLGRDWNAHEKHPIEIRASHHPVGHERHVSRLMFVQDADGEYKEFAMLETRTAQLPIGTKALSCMVGIDPATASATIGLPGNEPIEITIRELKNFSYAGLVFNAESVNLEFGTVPIPDKTVKIKIDALTLGELDSDSAQQLKEINYLKNGNPLKLKLTSISETGDQAFVLGESPNGNFLKINKINFYDFSGQTFNDQDYRKLTIETSASKTRDAVFLNGEPLGVLHFKKDKDALRQLGLLKTGQLTLAPAIIESNFSVICAQINPNTVEYPQKWTKEFQAFGTQSVNPQQQEMIESSAKILHHIKERPTFLFSTESNKKLGVMGLAVDNQKAETVTKWLTAQKVEWQQVPIEDVIRETKKGLAVFNLVDSSIPAKTLESMAKKFGAVIETDSEYQQRVNSLATRPQFLKPPEQTAQSPPNQSTLLLSTTPFTSDISNGAKTEPLSVEKLPTVTIDDLRNWYNAADKLGKPEDYKKRIVEVAYGFKAGEQLSAQALTVMNQDKFELEAISRLTQIAQRIGMVWGKSDENGIQVQGKIYDLAFNTQQRDLTISQKNGEVILNLQSGQVQTNKLTPQILQTFEDANSQIDKILAKNKSQELEIQR
>NZ_CP046705|112551:178095|142623_143133_+|WP_114086244.1|DBSCAN-SWA
MYFEGANPTATAALEQFAAELREWFDFRLEQERQTIEIQALKASDAKATRLAAHKLENLQAWNEAQESRKKLRKQRSEKFKSNLFWFGQWIGSGRSGIFFFICGVLISTTATAVAIINLPTFLSCPNSKSLCYQVYQMRFNNKSVILPGQAKDIVAEYERNKTKSKRRK
>NZ_CP046705|112551:178095|161263_161833_-|WP_114081709.1|transposase|DBSCAN-SWA
MILNCLEKHLAPGKCVRYLCQDETRVGLKTLTGKVITASGVKPTVEVKWPRENFWIYGAIEPLTGDHFLYEYPKLNGECFQQFLDWLSQQLGGDYAILQVDQAPAHTSSAIRWPENIIPLFQPPSAPELNPIERLWQLLKKPLKNQLFSSLQNLRDRIQEIFNQLTLEQVISISSYNFILEALFYAASY
>NZ_CP046705|112551:178095|163345_164002_+|WP_114080955.1|DBSCAN-SWA
MNSLTGLAEDGHMGWELQLNALPSKCTLLENVVNSDIDAEYLLFVRRYFSLRREQQSRVNKFPYGEAEYKQFVDALEELVETHSGIENRYCDLSRRFDWIKWLLMKCALSEEEESLAVTAITGQSNVLPSARSTQGFPIRWTPADKCELIHIWLSGITEEDIKSKYAPVLMYDAHLYKWHQTRDTDEAFGWIVRDFTALKRFYEDVVDNSEAVLVVTD
>NZ_CP046705|112551:178095|156092_156884_+|WP_114086238.1|DBSCAN-SWA
MKQIVLSLIANAGGVGKTTLSVHLAYEIVRRGFSVAILDLDPQRSLDVFCGIPPAEVSNTLVKALSKDFKGDWKLISVWEESKIQVCQGHPLMAEMANELVIRKRGEYTLSDRLKNYPLPHNLVILDCPATLGMLNVNALAASTHILVPVQLEMKAISGSAELVEWCISTSDELQLSPRPPILGFVPSMYDDTVAMHRQYLEQLPEITEHLQLKLYPKVRSSNEFKNASAHGLPLQKYRPKHPACKDFKQITDDLVALIKEKK
>NZ_CP046705|112551:178095|139639_140746_+|WP_159402646.1|transposase|DBSCAN-SWA
MPAKNHLSKEQKERLLKTLKEHENPYVREKILILLLMNDGKTYQEISKFLDIAYPTVAYWAVHGDPDNLESFLDGRREGNFRKVTKEYEDLLLETIEKEPLDYGYDFGRWTAARLATYLEKITGIKLSGSQVGRILERKKYVYLWAKYSLEDKQNPEIRKAFKEKLSEYLRITNVAPERLQVWFWDESGFSLRVIRRKNWGKKGTRKQITGQRRRGRVNIMGGLRYHDKKRMNFVIKKGNADVFYEQLKSLNNFLLQEWIEQGNPIETFNKCSAKIVIILDNASFHKRKDILVRIKAEMPNIILEFLPPYSPDYNLIELVWHSAKEYIAHRLFESVSQLEELLNKLLNEGGLIIKWERKIKNKGNAIY
>NZ_CP046705|112551:178095|173559_175083_+|WP_114081107.1|DBSCAN-SWA
MPKKSQSNSLSKIKQETSVGSRIFEALTEGEISQLLDELFAVLSDEQRVTVFAQLQGNTQETLTQIIAPPQTVEQVKTSKVQPTSLAKLAQTWSQLWGEWNQIILSASQSEGKYIVQEASWEEPYFDDCTFVEDLEAVAQKMKPLVKTAFENGFSNDNGFAASLLSAESEISNGIPDWMEIANGIHLEGATTSSLLEWEWLLVQSQGQNGFKLAQKIRELDEEFYHTSLDDDAVTDFFSHLPDVEKKLIFDGLTANREVSLWKHDLENTFSYWHIVYMELMQQFATPEIYLNNLRATISQEWQSGLPVIEDLLAKQEYRESLTVIQETLDALLKNKHDLNPWTPENSLLFVAVGGFSYAPGNWEKEKTLLRYYQQAVRELGEIERVNALSIQYITFECCYDWSSMFKAFAEIAVNKETQQALFTSWRESIIKRGTPYRYSGLYAHQKPVDTWWLHWLLDSITTKEKGHTWFRQQIIEWLENLPREQGQLGGEYSQDLRNWHSAIAIL
>NZ_CP046705|112551:178095|126806_126947_+|WP_159402645.1|DBSCAN-SWA
MNNFSKSIRQELGDFLDLCRCEGELWMFPPIGYLLLLTTLLAVDKT
>NZ_CP046705|112551:178095|155634_155805_-|WP_159402648.1|DBSCAN-SWA
MKPPKVEPQVTGKRNKKKIDSPPATKPHIPFQDRPEEPELPPEPCQHCNSWIATRR
>NZ_CP046705|112551:178095|172174_172414_+|WP_109013342.1|DBSCAN-SWA
MKVRRIIKLEVDVPGLGDRIKQAREARGRPVTQMAKEVGISRNYWYQLEAEAVLGGVAEETLRKIEEVLGVDLGVQFDD
>NZ_CP046705|112551:178095|151503_151794_-|WP_114086248.1|DBSCAN-SWA
MTEKLDLAPIKIRLKENYRERIFAESQQLGKSYLETLYFIIDCYFVFIKAGLATQQVAFTPITTDENKLPSMTSTPFAQEKEEDSEPETFSLDFDL
>NZ_CP046705|112551:178095|160234_161185_+|WP_114081388.1|DBSCAN-SWA
MSSLSSDMVRIYLQEIGKYPLLKPDEEIAYARLVQEMIAIEQSKNELTQQLEREPTMTELANTVEKTETQVRSALHLGQKAKQKMVTANLRLVVSVAKKYQNRNLEFLDLIQEGAIGLQRGIEKFDPNLGYKLSTYAYWWISQAITRAIAEQSRTIRLPVHLTEILNKIKKVQRESFLKLGRHATAEEIATSLNISPDKLREYLSASRTAISLNKKIGDEQETELGEILTDVGVSPEKLLTQELLSQDVAKFLEPLTPIQRQVLTLSFGLENDQHFNLAQIGQQLNLSRERIRQIQVKAISILRHRQSDMQEYLID
>NZ_CP046705|112551:178095|172565_173474_+|WP_114081106.1|DBSCAN-SWA
MSKPPSNRKKATSAASTDSTSAANSANEDISQQVDPGSATITVTAVEVTELTQEEQSDRLHLERKVERAFFEAGKALTELRDRRLYRSTHKTFEDYCRDRFGHSRRQSYLLMDAAVVFDNLMEKCDPMDHILPTNERQVRPMTKLEPHQQQEVWVKAVEQSGGKVPPARIVKNVVQQIMERTQVPNTYQLGEVCQILVKDNPELRGKGGCWGIVSAVNNFSCTVKTWDGEYAVALQHLKSYNYLPVECQQMQVICDRINQVYSSELEESVQKFLESLGRLKRAYLTALEEKLLSLLEAEIAN
>NZ_CP046705|112551:178095|149739_150219_+|WP_114086242.1|DBSCAN-SWA
MLDKLIKYFVYATKGYITKTQLIKFLYLADLYSVKWTGKQLTDLDWCYYQFGPWNEGIDTALNQMNGKEIVQESQYNATYIRPVNQAAHADDLDIPLSIKFVLDNIRREWAGSEKLNQLLEYVYSTAPMVEAKNTHRPEEKVKLNLQAEREKLVSELGL

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
109731:109748	attL	NA	NA	NA	NA
WP_114085050.1|112551_113481_-|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_114085049.1|114111_116238_-	AAA family ATPase	U5J9B0	Bacillus_phage	1.5e-48	27.8
WP_114085048.1|116707_117100_-	hypothetical protein	NA	NA	NA	NA
WP_114085047.1|117602_117914_+	hypothetical protein	NA	NA	NA	NA
WP_114085046.1|117971_118442_+	hypothetical protein	NA	NA	NA	NA
WP_114085045.1|118444_118783_+	hypothetical protein	NA	NA	NA	NA
WP_114085044.1|118776_121515_+	DUF87 domain-containing protein	NA	NA	NA	NA
WP_114085043.1|121511_122054_+	hypothetical protein	NA	NA	NA	NA
WP_114085042.1|122031_122724_+	hypothetical protein	NA	NA	NA	NA
WP_114085041.1|122754_123813_+	hypothetical protein	NA	NA	NA	NA
WP_114085040.1|123809_124529_+	hypothetical protein	NA	NA	NA	NA
WP_114085038.1|125979_126810_+	hypothetical protein	NA	NA	NA	NA
WP_159402645.1|126806_126947_+	hypothetical protein	NA	NA	NA	NA
WP_114085037.1|127335_128529_+	hypothetical protein	NA	NA	NA	NA
WP_114085036.1|128525_130289_+	type IV secretory system conjugative DNA transfer family protein	NA	NA	NA	NA
WP_114081708.1|130656_131157_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_114081709.1|131147_131717_+|transposase	IS630 family transposase	NA	NA	NA	NA
WP_159402646.1|139639_140746_+|transposase	IS630 family transposase	NA	NA	NA	NA
134579:134596	attR	NA	NA	NA	NA
WP_114086246.1|141343_141778_+	hypothetical protein	NA	NA	NA	NA
WP_114086245.1|141904_142711_+	hypothetical protein	NA	NA	NA	NA
WP_114086244.1|142623_143133_+	hypothetical protein	NA	NA	NA	NA
WP_114086249.1|143550_144054_-	hypothetical protein	NA	NA	NA	NA
WP_114086243.1|144128_148916_+	hypothetical protein	NA	NA	NA	NA
WP_109012819.1|149212_149473_+	hypothetical protein	NA	NA	NA	NA
WP_114086242.1|149739_150219_+	SocA family protein	NA	NA	NA	NA
WP_109012817.1|150220_150823_+	type II toxin-antitoxin system PemK/MazF family toxin	NA	NA	NA	NA
WP_114086248.1|151503_151794_-	hypothetical protein	NA	NA	NA	NA
WP_114086241.1|151799_152759_-	ParM/StbA family protein	NA	NA	NA	NA
WP_114086240.1|153870_154971_-	hypothetical protein	A0A7T5	Microcystis_virus	4.9e-99	53.8
WP_159402647.1|155276_155543_+	hypothetical protein	NA	NA	NA	NA
WP_159402648.1|155634_155805_-	hypothetical protein	NA	NA	NA	NA
WP_114086238.1|156092_156884_+	ParA family protein	F0PIG8	Enterococcus_phage	5.0e-05	23.8
WP_114086237.1|156886_158005_+	ParB N-terminal domain-containing protein	NA	NA	NA	NA
WP_159402649.1|158186_160145_+	ATP-binding domain-containing protein	U5J9B0	Bacillus_phage	3.1e-27	30.2
WP_114081388.1|160234_161185_+	RpoD/SigA family RNA polymerase sigma factor	F4YCU2	Synechococcus_phage	4.6e-37	34.6
WP_114081709.1|161263_161833_-|transposase	IS630 family transposase	NA	NA	NA	NA
WP_114081708.1|161823_162324_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_114080956.1|162414_162921_-	DUF1993 domain-containing protein	NA	NA	NA	NA
WP_114080955.1|163345_164002_+	DUF1877 family protein	NA	NA	NA	NA
WP_147262459.1|165631_165925_+	hypothetical protein	NA	NA	NA	NA
WP_147262458.1|165921_166215_-	hypothetical protein	NA	NA	NA	NA
WP_114080952.1|166224_166803_+	PEP-CTERM sorting domain-containing protein	NA	NA	NA	NA
WP_114081802.1|169836_170565_+	hypothetical protein	NA	NA	NA	NA
WP_114081105.1|171599_171845_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_109013342.1|172174_172414_+	helix-turn-helix transcriptional regulator	A0A1L2BWW8	Bacteriophage	9.5e-08	47.1
WP_114081106.1|172565_173474_+	hypothetical protein	NA	NA	NA	NA
WP_114081107.1|173559_175083_+	hypothetical protein	NA	NA	NA	NA
WP_159402562.1|175215_176229_+|transposase	transposase	NA	NA	NA	NA
WP_159402646.1|176988_178095_+|transposase	IS630 family transposase	NA	NA	NA	NA

Sequences of DBSCAN-SWA_3

Nucleotide sequences of DBSCAN-SWA_3

>NZ_CP046705|186481:233000|DBSCAN-SWA
TTTAATATGAAGCTGCATAGAAAAGAGCTTCGAGAATAAAGTTATAAGAAGAGATAGATATTACCTGCTCAAGTGTAAGTTGATTAAATATTTCTTGGATGCGATCGCGTAAATTCTGTAAAGAAGAGAAAAGCTGATTTTTGAGTGGTTTCTTGAGGAGCTGCCAAAGCCTTTCAATGGGATTGAGTTCAGGGGCTGAAGGTGGTTGAAACAGAGGAATAATATTTTCTGGCCAACGAATTGCTGAACTTGTATGAGCAGGTGCTTGGTCAACCTGTAAAATAGCGTAATCCCCACCTAATTGTTGAGATAGCCAGTCCAAAAACTGTTGAAAACACTCGCCATTCAGTTTTGGATATTCATAAAGAAAATGATCTCCAGTCAATGGTTCAATTGCACCATAAATCCAAAAATTTTCCCGTGGCCATTTCACCTCAACAGTAGGCTTAACTCCAGAGGCAGTAATCACTTTTCCTGTAAGAGTTTTCAGTCCCACCCTCGTTTCATCCTGGCACAGGTAGCGAACACACTTGCCGGGTGCTAGATGTTTTTCTAGACAATTCAGAATGATACCGAGTTTTTTTTAAACTCAGATACTAACTTTTCATCCTGCTTATGGCTTTGAGGACGTGGTACTTTTAGTTTTGCCCCTAATCGATATCGAACCAATGCATAAACCGTTGCATACTCGATATCAAGCCCCTGCTCTTGCTTTAACCACTCTACTATTGCACCATAGCTACTAAAGCCTTTTCCTGTTTTTAACTCCTCTTCAAGTGCCGTGATCGCTCCTTCAGGAATTTTCCGTTTTGCTCCCGGAGCTTTTTTTATTTTCAATAATTCATCTAGCCCACCCGATCTATATTTTTGTAACCATCTTGTCACCGTTGATGTATCTTTAGCCAAGCGTTTTCCAATATCTTGCTGCTCCTTGGCCTGCCCGCTTTTTATCCACCACAGCATAATAAGTTTTTCTTTCTGGTTCCCTAAATTAGCTGTTTGTAGGCGTTTTTTAAGTTCTTCTTCGCTCTCTGCGATTTCAATCTCAAAAGGGCGGCTCATGGTTCTTTTAATTTATCGAGTTTGTTTTCTCTATTATATGCAGCTTCATATTAAATTGGTATAACGTAGATTGTCTCTAGTCGCCCTGATATTGGCTATTGGATTGATACCAGTTGTGTTGGTGTAAAGCCTTGTGCCAATGAGTTAAAAGGATAGCGATCGCCTACAGCAGGCAGTTAGGCTATCTTGCTTTATTCTCCCGAACTTAACTCAGATTGGTTCAAAATTGCCTCTAGCAATCCAGTCGATAAGCTGCTAGTTACCATGTATTTACACTGAATGCTTAATTACAGAAAAACTTTTAGCTTATGTTCTACTCATAATTATTGCCTTTAAATTACTTAATCTTCATCACTTAAACTAAATTTAAACTCTTCACTACGGCTTTACACTTATTAATGTTTACTTTACAGCTTCTTGAGGCTAATATCATTACTTTTATCATTGTGATAACAGTTTGAATGATTGATATTAGAGAAGTAGTTTTAATTCGAGTTGATTAAATCAGTGAATAAGAAATGGGCGACTAAACGACTCACAATTAATTTGGCATCAGGGGAAGCAGAAAGATTAGAAAAATACTGTTCAATAACAGGACGACCAGCAACCGATGTAATTCGAGAGTTGATTCGCTCTTTGCCAACCGAAGAAACACCAAATGCAAATTGAACCGCTATTCTCACACAAGTTATAGTCACAACGATTTCATACTCCTTGGATCTTTATCGGGGAGCTTTTGTGTTAGAAAATCTACTGCTGAGGGAAAATTTAAAGTAAGACCCTGTGTTGAATAAACTAAGAGGATTCATATTACAAATTATCGAGGTTTTATTCTTAGTCAGCAACCTCAATCAACATGAAAGTATCACCCGACAATAGCTTTACGATTTTGACACCTGATGAACTTCCTATAGTTCTGCAACGGCTGAATGCACAAGTTGAACCGACAAAAATATTATTTTTCTGATTTTTAGAAAATTCTAGAGGTAAATATGATTAAACGCATAAAAGGATTATTTTTGACTGCAATTTTGACTGTTTTATTTATTGGAGTAACTGCTACTCATACAAAAGCGGAGACTTACCTTGCTGGAGAATTTACAATTACTTTGGATGATGGAGAAAATGGCAAAACCTACAGAGGTTGTGATGCTCAGGGGAAATGTATAAATTTAGAAAATGGAACATCTTGGCGTGATAATGGTTATCGGGGTATTACCTGGGAAAATGGCGATTATACTTATTCAGTTTCCTGGCGTGAAAATGCCAATGAAGGAATGTATTTGAATATTTACAACAAAGATAAGCAGATATTACGCCGTCAACTAGTAGAGACAACTGAAAATGTAGGAACTCTCAAGGGTGTAACTTATTGTGATGTAGTAAATATTACATCTGGGCAACTGGCACTTCGTGATAGCCAGAATGGACAATCTAGGGGAGGTCTTGATAATGGCAATAATGTTTTGTTGAAGAAACAAGAGGGTATCTGGGCTTATGTAAGTGTCGTTCAAGGGCCCAATACTAGAATTAATGGTTTGTCAGGATGGGTTAATTCAAATTATCTACATTGCACCAAAGAACCAATTGATTAACTAAGATTTGATTTGCTCTATTTATAAGCGATCGCGTCCCATCCAATGGGAACCATGTTATGTAATTGCGTTCCTTGGCACCATGAAATTATTGAATTTTCTCAAATCCAGACCAGTCATTATAGTTTTAGCAATTGCAGTAAACATCACTGGTATTGATGTACATTCTTCTACTTCAAATTTTCCCATAAGGAAGAGTACAATTACTCAGTCCCAACCACAGATTCAACTTGTTCACACACTGACTGGGCATAAAAAAGTGACTTTTGGTGTTCGAGCAGTTGCGATTAGCCCTTCCGGGCAAACCCTGGTTAGTGGAGGTAGAGATGATACGATTAAATTCTGGAATTTACGTACTGGGAAATTACTGCATAGTTTAGACGCTCAATCAGATGGTATTACTTCAATAGCTATTAGTCCAGATGGTAAGCGAATCGTAACTGGTGGGATAAGCACCCCAACAATGAAGGTTTGGGATTTACGCACTTTCCTTATGCTAAAGGGCGACAGTGGGCATACCCAACCAGTAGAAACCATTGCGATTAGTTCAGATGGTAAGGGACTTCCAGAGAATAAAATATACAGTCAATAAAAATGATAATCATTTTAAGGGGGAGAAAGGGGTTGCCAACGGCAACCCCTTTCTCCCTCAATAAATAGGCAAGATAAATGTCTGCACAAAGAGAGTTCTTAAATGCAGTGAGCTGAATTGCTATCGACTATTTTTGCGCTTTTAACTTTTTGAAAATTACGTTACTCCACAACAGATATCAATAAACCACTTACCTAAATTTGGTAAATTATCTTCGGTAAAATTAGTCAAACGTTCAATCTTATTTTCAATTTCTTGCATAGCTTTTTTAGTTAGACGGACTCCGCTAGAGTAAGTCTGAGTAACTAACTTAACAACTGGACTTTTACCATTCCACGTCATAGTCTTAGCAAAATTTAATGCAGTTTCCACATCGTCTAAAATACTGCCATTCCAATGATTCTCCAAAACAGCCCAAGTTCTTTCAATTGGATTATATTTACTGTGATAGGGAGGGTAATAAGCTAAACGTATATTTAATTTGTATGATTGAGCAAATTCAACTATACGTTTCATAAACTGAGTACGTCGAGAACTATTTTCTCCTCCATTATCTTGATTAATAAGTAAAGTTTTTATTTCCGAAAATCGCCAGCTTTCTGATTTCCAAAAATCCCCTAAAATGTCAACGATAAAATCGCTAGTTACTTTGGATTCTGTAAAATACAAAAATAGCTCGTCAAGGTCTGGAAGAAAGATACCATAAGGAGCTACAGTTGTTTTTGGTTTGAAGTCGTGGTCATCAGTTTCTGTTGGTACTCGATTTCTACCACCACGATCAAAGGAGCCGATATTTACGCGAGCTTTCGCATCCAAGCTTAAACGTAAAATAGTTGGGTCATCTGAAGCTTCTTGGTGAACTATAGCTAATTGCTCAAAGATTGCATCAGTTTCGGGAATTTTTTTTGAGGTTGAATTTTGGCAACCCTCTTGAGGCGATACCCTAAATCATTTAACTTGACACGAATTGTTTCTGAAGTTGGTAATTCTTCTTCAGCATAACCAAATTTTTCAATTAATTGATGTCTTACAACAGATGCGCCCAGTCGGGTATAGAGTCTTTGACTTTTAAAAGTCGGGTCTATTTGACTTTGAGAATCGACTAGTTTTTTGATATCTTCTAAAAGAGTTGGTAGGTGTTCTTCTGCTTTTTTTCTTCCTCTACCTTGATAATTATCCACACAAGTGATACCACTATTTAATTCTTTAATTCCTTTACCAATAGTTACACGGTTCCATCCTAACTCTCGCTCTGCTATAGACTTTCCTCCGTGTCCTAATGCCACAACTGTTTGTGCAATGAACCTACGTTTAGCTGCTCCCTTTAATTGATGTGCGGTTTCCTTCAATAACTTTTTCAATGAATCTGTTAATTGTATTGACACCTCAAACATCCCAAAATCGAATCATCATTCAATTTACTACAACTTGGGGTGGGAGAGGCTGCCGTTGGCAGCCTCTCCCACCCCCCTAACAATGATTATCATTTTTATTATCTGTATATTTTATTTTCTGGAAGTCCCTAAATTGATTGCTAGTGGCAGTGATGACCGTACAATCAAGCTTTGGGATTTACACACGCTTAAGCTGCTTGATACCATTCCTGCACACTCAGGATTTGTGAGTAAAGTTGCATTTAGCCCTGATATGCAAACCCTTGTGAGTAGTGGGGGTGGCGATGATAATACAATTAGGCTGATTGATTTACAAACCAAAAAAACACGCCATATTCTCAAAGGACACAAAACCGGAGTTGATGCTATTGCCATTACTCCAGATAGCAAAAAGCTTGTTAGTGGTAGTTTTGGTCAGCTAGTTTCTCGAAATCGTGCGATTAGTACCCTAAAGTTATGGAATCTTCAAACTGGAAAACTACTGCATGACTTTACTGATAATTTTAATTCAGTTGAATCTCTTGTGATCAGCCCGAATGGAAAAATTCTGATTTGCGGCAATTATGATGGCAGTATTAAACTGTGGAGCTTAGAGACTTTAAAGCCGTTGCATACCTTTCAAGATGGTTCCAGTTCTGTTTTAGGGCTTGCTCTGAGCCGGGATGGTAAAACCCTTGTTAGTAGCAATGAGGATAGTACTGTACATATTTGGCAAATTAAATAACTGCATTAGCCCTATTTTTGGCACATGGGTACTTCTAAAAGCAGAAGCTGGTTACGAATACAGAACTTAACTTTAACTAATTCGGTGGAATTCCGCATCCGTCTACACGGTGGGGATGGATAGCCGGGTGATGACGAAAACACCTCCGACTAATATTAACCGCAGGTTGATAAGGAAGTGGGGTGTTTGAGAAATCACCAACATTATATTTTATTACTTTACCACAATTTGTATTTATGATAAAATAAACACATCAAGGAGGTGAAAGTGAAGTGTTACACAAGGTTGTGCAAGTCCGTTTATATCCGTCAGTTGAACAGCAAAATCAGCTAGCTCAAACTTTTGGGTGTGCTAGATGGTGGTGGAATTATGCTCTGAATAAATCCGTTGAGACTTATAAGGAGACGGGCAAGGGACTTAGCCGTGTAGCACTCAACTCATTTCTGCCTGCACTCAAAAAAGCTGAAAATACTGCTTGGTTAGCTGATTGTTATAGTCAAGTTTTGCAAGCTACGACACTCAATCTAACTACAGCCTACAAAAACTTTTTTGAGAAACGTGCTGGATTTCCTAAGTTCAAATCCAAGCATGGTAAACAGTCAATTCAGTATCCTCAAAACGTCAAGATTGTAGATGGTAATGTCAAACTCCCAGGTAATATTGGGGTAATCAAAGCCAAAATACATAGACTCATTGAGGGGAAAATAAAGACTGTTACTGTGAGCAAAACGCCCTCTGGAAAATACCTTGCATCTATCCTGACTGAGTTGGAGGGTGAAAATCAGGTTACTTCAGAAGGTAAAATTTATGGCATTGATTTAGGACTAAAACACTTTGCTGTCGTAACCGATGGCGAGAAAGTATCTTTTTACGATAACCCTAAACACCTTGCCAAACATGAGAAAAACCTCAAACGTAAGCAGAAAAAATTAGCACATAAACAAAAAGGGAGTAAATCAAGGAATAGATATAGAAAAGTTGTTGCCAAAGTGTACGAGCGAGTTAGTAACTCAAGGCAAGATTTTCTACATAAACTTAGTTATAAGTTGGTCAGCGATAGCCAAGCTGTCATAGTAGAAAATCTTAATGTCAAAAGCATGGTTCGTAATCACAAATTGGCGAAATCAATATCTGATGTGGGCTGGGGAACATTCACTAACTTTTTAGCCTACAAGCTAGAACGCAGAGGTGGAAAGTTGGTTGAGATTGATAGATGGTTCCCTAGTTCTAAGCTTTGCTCTAATTGTTTCTATCAAATAGGTGAGATACCATTGGATATCCGTGAATGGACTTGTCCTCATTGTCATACTCATCATTCGCGTGACGCGAACGCCGCGCAGAACATTAGAGCAGAGGGCATCAGAATGATAAAGGCGGAAGGTTCAGCCGTCTCTGCTGTAGGAGGGGAGGTAAGTCCTACTCTTGGGCGAAAGTCTAAGTTTAGGCACTCCCTAACGATTACAGAAGCCCCAACTTCAACCGTACTCGGTAAGTTGGCGTAGTTCACCTATCGATATTCTCGCTCAAAAAGTACGACTAATTTCAAAGTAAAATTTTCACTAGTTTTTGGAGTTGCTAGGGAAGCCCAGAATAAAGGTAGTATCTGAAGATGATGGAATCCCCAAGAAGTTATTACGATGCTGAGTTTGGACAGATTATATTGGAAGATAACTATTGGACTTTAGCACAATGTGCTGTTTTGGGAGATCGCCGTGTACCGATTTGTTTGGATTTTGAACAGGGGCAGATTGGGGAACTTTCATCACTTCAGCGTGAGGCTATTCGGCAAGCTCTAGCCTTGCCACCCGATGTTTTACACGTCACTGCTCCTCTGGTGCTGCAAAATTATGATGTATATCGTGAGATGATTGTAGATGAGTCAATGCCTCTGCTGGCTAATCCCATTCAGGTCTGGGAGCAGGTCACTTTCTCATATATCTATGTGGAGTATGACCTAGATATTGCTACCTTTAAGTTGATAGCTGAGTGTGACTGGGAGCCAGAACACGGCTTAGAAGTACGCTTTCGCAATGGAGTAGCAGACGATGTAGATCAGATAGGTGAAACAGGACGGTAAAAACTATATAGCTTGGCATAAAACCGTGGTGAATTGAAGCATAGCGCTTATATACTGCGATCGCTGCTAGAGAAACCAAGTATCGATTGCCTATTGAACGCTTCCTGGCTGTTTTGTAGTACCTATGGATAGATATCCTATCTCTTTTGACTGAATATGAAAGTGGATTTATCTAACCGAAAGTGCAACAGTTACAACAGTCAAACATTTAGGAAAACGAAATGGTAATGATCTATCGCGCCAAATCGATACAGCAGTAGCCGTGCATTGTTAATTTTCGCGTGTTGCTAGAAAATTATTCCTTTTCCCCTTTATGAATAAGAGGTAATAATGCTAGATTTCGATTACTTGCAATGATTCAGGGTGATTTATGAACAAAGGCGAATTAGTGGATGCTGTAGCAGCAAAGGCCAACGTCACAAAAAAGCAAGCCGATGAAGTCATCAGTGCTTTTTTGTCAGTTGTTACCGAAGCTGTAGCGAATGGTGAAAAGGTAACGCTCATAGGGTTTGGGTCATTCGAGCGACGCGTTCACGAAGTGTGCCGAAGGTATCGCTCAGAGCGCGAAGGGCGTAATCCGAAAACCAATGAGCCAATGACTATTCCAGCGACCAAAGTGCCTGCATTCTCTGCTGGTAAACAGTTTAAAGAAAAAGTAGCGCCATAGATTAATTGCTTTAGCACTGGCAATCCAATCACTGCAAAGCCACAATCGATTAATTCAAGTATCGAATCGACTATGAAACTTTGACTGCTTCTTGGTTTGACTGCTTCTTGGGGAGTAATGTTACTGCAATTAGACAATTCTGGCATTGACTTGGGTTCATAAAGAAGTTGCAAATTGCTTGACCTCTGAATAACAGCAGCAGAAGTTGAGCATTAATTACTATTTGCTCAGAGAATTATGTCTTCTATATTCAATCCGAACTTGTTTAACGTCAATTTGCCCAGGCTCTAAAAACACAAGTTGCTCTACTTGGTATAACCCTAAATCTTTAAACTGTGCTAATTCTGAGTTAGATAATGGCCAAGGTGGGCCCGATGGTTCAGATTCTGTGTCTCGAATACGAGTAATCATCAATAGCGTTCCACCAGGAGCAAGTACAGAGGTAACTGAAGAAATAACCCAAGAACGCACATTCAAGGGCAAAGCTTGAATATTGCGACATTCAAAAACAAAGTTAAAAGCTTGATGCCATTGTGAGGGAATTGCTAATAAATCTGCAACTATATAGTTGACAGTTGAATTAGGAAATCGCTCTTGGCACCAAGCGATCGCTGTTGGTGAAATATCAAATGCAGTTACTTCAAATCCCAGATTTACTAAAGCTTCGGCATCGTCTCCCAAGCCACAACCAATTACTAACGCCTTTTGCCCAAAAGCGAATGGTTCATGATTCGTCAACCAATCTTGCAGATAAGGATGAGGAGCTAACTTAGCCCAAGGAATTTGTGCTGTGTCCCCTTTGGCTTTGGCATATAAAACTTCAAACCATGCCGAGGGGTCTGATTTTTGTAACGCTTCTGTAGCTAGCTGTTTAATATAAAACTGTAAATTTTCCGGTTGTTGCTCCAACATAAAAATCGACACCACTCCATTGTCAATTATGGCAGTCTATACCAGTTGAACTGAAAATCATAATTGCAGGCTAACTTACGTGAACTAAAAGTTGTGAATGATCTTTTTGATTGTGCCTCCTCAAAGCAAGCATCGGTTTACAGTCCTAGCCAAGATGAACCAAATACCAATTACCATTCACCATTAGGTGCATTTGTAAATCTGGCTTCTACCGTGCAATATAAAACTGCCCTAGACGAAAGCTGGAGCAGTTTTTGATAGAAGTAAATTATATAGGAGACAATTAGTGTTGTCCCCAGTTTATCCATAATAAATACCGTTATATAATACTATTCACCTCAAGTTTAGTGCTTTACGCAAAAAACGAATAATCTTGAAGTTGGCATTACAAAGTTTAGAAGTCAACATCAGGCTTTGAGTCTTCCTGATGTATTGCTAACCAAGTTTTGTAAATCAATGCTCAGAGAGTAAAAGTCCCTAGCAAATTAAGGAAATGAGCCGATTGCACATTCGTGAAGATGACCTGACAGGTAAAAATATTGCTAACCTTTTGAGGGAACATCTCGAAAATATGCATGAGATTACCCCGCCCGAAAGCGTTCATGCTCTTGATATAGAGGCATTGCCTTCGCCTGATATTACTTTCTTTTCAGCAACGGATGGCGAAGAACTGGTTGGATGCGGGGCATTGAAAGAACTCTCTTCAACAAGTGGCGAAATCAAATCAATGCGTACAGCCTTGGCTTACCGCCGCCAGGGTGTTGCCTCCAAAATTCTGGAACACATTATTAAAGAAGCCCAACGGCGTGGTTACGATTGCTTGAATTTAGAAACAGGGGCAATTTCAGAATTTGCTTCAGCACGAGCTTTGTATACACGGTATGGGTTTGAGTACCGAAGCCCCTTTGGTGAATACATTGATGACCCGAACAGCGTATTTATGACGAAAAAGCTTGCTTGATTGGTTAGTAACAATCACCGTTACTGCTGTTGAAATTCCAGAGTTAACCGAGCAAGAAATTAGCGATAAGCCTGACGGCATGGCTACGCTTACCGCTTGCACTTGGAGCGAAAGGTAGAACGGGCGTTTTTTGAGGCGGGAAAGGCACTTATGGAGTTACGCGTTCGTCCTTGACGTTGCCGAAGGCAGTAGAGGAAGCGGGTGGTAAAGTTCCAAGTGGTAGAATCGTCAAAGACATTGTGCAGCGCATAATGGAGCGAACCAGAGTACCAAACACCTACCACTTGGGCGAAGTATGCCAAGTTTTAGCCAAGGACAACCCCGAACTCAGAGGTAAGGGTGGGTGTTGGTGTGAGGTAAAAGTTATTTGCAGCCGCTCAAGCGAACCGTTAGCAGTAGTTACGATGCACTTCAACAGACTAAGGACAAGCAATTAAATCGAAATTACAATCATTACGAGACAAAGTAATCATGGAATTCAACCCAAACAACAATGTTGTTAAACTCTGTCTTCAAGGTATGGGCATGGAAGAAAGAGGCAAACCAGAAGAAGCAAGTAAACTGTTTCTTCAAGCCTGGAACGAAGCGACATACGACTTTGAAAAATTTATTTCAGTCCATTATGTAGCTCGATATCAGAAAAATATTTCTGACAAATTAAAATGGCTCGAAACGGCTTTGCAGTTTGCATTAAAAATAAATAACAACACTGTTAAGAGTGCTTTCCCTTATCTATATTCAAACATTGCCAAATGCTATGAGGACTTAAGCGACCCTGACAAGGCAAGAAAGAATTATGAATTAGCAACTTCGTTTAAGGATAAACCTTCTGACAAAGGCCCCTTTTATCATGGAACGAAAGCAGATTTGCAGGTTGGCGATTTGCTGACAGCAGGAGGCAGTTCTAATTACAAACTTGAACTCAAAATGAATCACATTTATTTCACAGCCCTTGTCAATGGGGCGGGACTAGCTGCTGCATTAGCAAAAGGCGATAACCGTGAACGTGTTTATATCGTTGAACCAACAGGGGAGTTTGAAAATGACCCGAATGTTACAGACAAAAAATTTCCGGGCAATCCGACACGCTCATATCGCTCCCAAGCACCATTAAAAATCGTTGGCGAAGTCACAGATTGGGTGAGACAAACACCTGAAGAACTCCAAAAATGGCGTGAAAAGTTGGCCAATAACAAAGGAGAAATTATTAATTAATTTCTAAGATTCCCACATCCTGCTCACCGATTGAAATCAACGGCCTTATTTAACGGCTGTCGAAGAGAAATTGTTGACGCTTCTAGAGTCGGAGTATGGAAGAATACCCTGAAAATTTTGGCAATTTGGCATCCAATGTCTTTGGGTTGCAGTTTCAATGGAGTTAGCAACGCAACGGGACAGTCAAAAAGTTGTACGAGGGAAAAGATAAAACTTCCCGCTTCTTGACATCCAGCTATGCCAGTTGTTTAGTTGAGTGCTGTAGAACCCCTCTACATGATTCATACAGCGTTCAACAGAGTTCAGTTCCCACTCTACAACTGGCTAGAAATTAACAAAACTCAATAGAATCTCAGAAGATGTAGATAACTGGCATTTCTCTAAGAGCGATGCCTACGGCGGGCTACGCCTACGCACCTGTAACTGCAACGGATCGATCCGGTCTGGGTCGCAGTGCTTAGGGGCTAAGTCAAATAACGTCGCCTGCTGCACTGGCTTGGTTTCCCTCACCTTCTGCTGATAGTCCAAAACCTGCACTTTCCACTTCAGCAGGGCATCAGCACTCATCACCAATGTCCCTGTCAAAAGTGCTGGTGTGGGCATTACAGATGGGAATAGGTTTAGCTGATTGGGTTCCAATATATTAGTGGAGTGTGTGCCGACTAGCTATTATCTCCCAGAACTGAAATGCAAGAAACCTATTAACGGGTTTAGGAGTGCGATCGCCCCAATTCAAGCCAGGAAAACTCAAGAGTAAGCGTAGCCCGTTGCAGACATCGCCTATATTCAACAATTGCAATAAACAGTTCAGTTTAGTAGAGTGTCACCCCACTGTTGTAAGCGTTCACGAAACTGGTGTAGTCGTACTGGACTTGAGTTGCATAGTCTAGAGCAAAGTTAACAATCTCATCTTTGAATACAGCCTTGTTACCGCTGGTGATATCAGTCACTTGCTTGTCAACGCTTTCTGAAACAATGCTAGCATCGTAATCTTGATCGGAGATAGCATGGTTTTTAGCAACGACCTTACCTGCATATCCCATCGCATCCATGAATTTTGATTTAGTAGTTAGTAAGGTATAGTCAAAGTCCACTTGGTAAGGGGATTTTTCATGCAGCATAAAGGGGATACCACTGACCGTAGTGTAGCCAACCAAGGGGTCAGTATTAGAGAGCATCGCTTTGGTGGCGATTGTCACCCTCGTCCCTTGATGATTTCCATAGACTGAACTTGGTAGTAAACCTGGAACTGCGATCGCTACGGCGCTAGAAGCTTGCTGCTTCATCTCCAAAATTCGGTCATCATCGGTTGCTGAAGTTGGGCCCTCAATCAGCAAGTAATACCGATACTTACCAAGACTACCAGTACCGGAACCTAATTTGAGACGAATATCTTTTAGGGTGTAGTAACTATTGCTGTAACGCTTACTGCTAGGAACTGAATTAATGTAGCTGCTCATCGCCCCAGTAATATCTAAGTAGGTACTGCTGGATACAGGCTGGAGTTCAGAGGTTGTCTGAAAAACTCGATTGCTACTACTATTTAGCAGCGTATACTTATTTAGCAAACTAGAGCGGCTCTTGGCTGCTGACTGTTGAATTAAATCCTTGACCACACCGTTGGTATTGCTCTCTTCTAAACGGTATGAAAGCTCGTCGTTAGTCCCCTTAAAGTCGCTCATCTTGTTGAGGTAAGCATCCAGGAAATTTCGGACAATATCTTGAGCATCACTGGAGCTTAGGCCGTTCTCTTTGGCTGCTAGAAGAATCGAGACTGCCATACGTCGCAAATCCCAAACGTAGGGGCCAAGATAACCTTCATCAAAGTCAGTGGTGTCAAAGACGTTATTATCATTGCTATTCCTCATTCCCCCAAGATTTTGCAGATGCATATCCCCCTCTAACCAAATGGCTGAGGTAGAGGAATTGACAAATCCTGAACCCGGTAATGTCTGCATATCGCGGTAGAAGATGTGAGCCGTTCCTCGATAAAAGGCGAAGGGGCTAGCTGTCATCTTTTGCATCTTCGTTGCCAGTTCTTGCGGTAATTGAGAAGCAAAGGGATGGTTGTATTGGTAAATTTCATTTTCCACCCAAGTTGAACGGGGAGTTGCAGCAACAGATGTAGATGCAAACCCCAAAGTTAAAATGAATACGGCTGCAATCTGCTGTATATGTTTGAGCATGAAAGTCTCTTAGATGGTAAAGAAATTAACTCTTGCTGGACTCTTGTGTAGACACAATCATCTAACAACAATTCATTTACCACCTTGAGTCATAACTTATAAAGTGATTTAAAGCACAATTTAACAACTATTCATAGCCAGTAAAAAGATTACCAGTAAAAAGATTGCTGTCAAGAATTTTACGCTGCCCCAATCAAGCGAACGCGAGTAGCGTCTCGTAGAGAGGAAAGTAGACCGTAGGCGTTGGCGTAGCCTCTCCAAGAGTTGCCCGTCGTAGGCATCGCCTTACTCCAGATCGCCAACGCCTTCACTTTCCTTTTTTCCTCTAAGAAATTCTTGGGTATCCATTTACACAAACTACACTTGTTCTCAACTGATGCCTACGCTTTACTGCATTACACTTACATTCTTCAAATCAACATTACCTAGTAGTTCGCCAACCCAAAATTGCTGGGTGGAGGTCGGCAGGGGAGCAGGGGAGCAGGGGAGCAGAGGAGAGGCAAATACCAAGTTCTTTCCCCTCTGCCCCTCTGCTAACCACTTTTGCATTGTTTCCTTGGCATACTACTAGCCCAGAAGATAGATTCGTGCTTTACGCAAAAAACGAATAATCTTGAAGTTGGCATTACAAAGTTTAGAAGTCAGCACAAGCGAGTGTATTACAGACATCATCCGCGACTTTGAGCTTTTTCCTTAATGGATCACAGAACATGGTTGCTGGTAATGGGGTGCTTAGTGAGGAAATCTGGGGATGGGGAAAGTAGCGACACCGGACAGCCCGTCGTAAACATCGCTCTCAAACTGGGGTAATCGCTCTAGTAAAATCAAAAACCACCCACATCATGTAAGTGGATATCAAAAGAGATTATGTATTTTTTGTCACCTACCAAACAGTTTATTAAGCACATCAGCTAGACGGTAGCCTGCCAAGCTCATCCGGCGTTCTGCTATTGGTTTGGCGGTAGCAGCATAATTTGGCGGTAACGGCTTTCCATCGTTTTTATCACTACTGCCAGAAAGCTTGCCATTAAGATATGCTTTTTGTTTAGCGATATTAAAACTCTCCAATTTTGCCCAATTATTAAATTGAGTTTCTCTTAACTCTGGCAATTTACTGCGTTGATAGTCGGCTCTTATCTTGGTTGCAGTGTTGCGAACAGTTTGAAAGTTTTCTGAGCCTAGTATGAGGTCATCCCAGAATTTATGCAAACTGATTGTTTGACCATCTGGATTAACTCTAATATAAAAACGTGTACCACCTCTATCACCTTCTGGTTCCTTATACTCGTTAGTAATTAATTTGGTAGTATGCAATGGCTGATGCACATCTCCTACTAAATGGAATAACCAGCATATTGCAACTGCTTTTTCGCTGTTGGTGGCATTACTTTGAATAATATCAAGATTTTTTTGAAAAGCAAATATAATATTTTCTTCACCTGGAATTTCACGAGTAATAGAGTTTGAAGAACTACCAGGTTGATAAGGAAAATTGATATAGTGCCAAGTTGGGTGATTAAATACTTGGTTATTTCGAGCTTCATCTGGCCATTTTGCCGCCCACATAAATAAGTACAAATTTTTATTTTCATCAGAAATATTAGATTGTTTGAGGGAATTCCAAAAGTGTTGAATGTTAAGAGAAATCCGATAAAAACAGCCCAAAATATGTTAAATTTTGGGCGGAAGATTAAAGTATATCTATTTGATAGTGATTATAAATTCATTTCCCAAGATTGTCAAAGATATCTTGAGAGGACTGCCAAAAAACGATTATCCAGTATTGAACAGTCGTCTGTTCTTTGAGTGCTGGCTCTCTTATGCTATGGATAACAGCTTAACAAGTATGCGAGATTTGTTTAAGAGATTAAACAACACAGGATTTGAAGTAGATATTTCTACTTTTTCTAAAGCAAACTTACATCGAAGCCAAAAACCTTTTCAAGAAATTTACCAAAAATTGAATGAATTAGTACAGAAGAAAGTTCAAAAAAAGTTGCATGATAAATATGCAATTTGTCCAATAGATTCAACAATTATTACTCTCACAAGTAAATTGTTATGGGTATTAGGACATCATCAAGTAAAACTTTTCAGTTCTCTAAATTTAGCTACTGGAAGTCCATCAAATAACTTCATAAATTTTGGACATGATCATGACTATAAATTTGGTTCTAAAATGATGTCTAGTTTACCAATAAATGCTGTTGGGGTGATGGATAGGGGTTTTGCTGGATTAAAATTTATCCAAGAATTAGTACAAGAAAACAAATATTTTGTTTTACGGATAAAAAACAATTGGAAACTAGAATTTGATGGCTCAAATGGGTTGGTTAAAGTTGGTGCATCTGGTGATGCTCAAGCCTATAGAGTAATTAACTTTTGTGATTTAGAAGCGAAAACCGAGTTTCGCTTAGTTACTAATTTACCTTCTCATGGAGAGGCTGCCGTTAGTGATGATGAAATTAGGGATATTTATCGATTACGTTGGGGAGTTGAATTGTTATGGAAGTTTTTAAAGATGCACTTAAAACTTGATAAATTAATTACTAAGAACGTCAATGGTATCACTATACAAATTTACGTTAGTTTAATAGCTTATCTACTTTTGCAGATATTATCTATCCCACAACAATGGGGACATACGCTATTAGATAAATTTCGCTATTTACAATCTTGTATGTGTCAGAAAATCAGTTATGTTCATTGGTTTGAGGAGATGATGTCATGTTGACTATTTTAGGCTTTTTAGAGTTAGTGTAACTAGATATGTAAAGTTTTGTATTAGGATTCAACATTTCTGAGGGAATTCCATTGCTGCTCAAATTTAGAGTATTCAGGGTGTTCCTTCAAAATGGCAATCATTTTCTCAATTACTTCTTGATGATTCTGTAAGAGTTCCCTGTAAGCGATCGCTCCTGAAACCATGTGTCCAGCCTTATTCCAAGCAAAAGCTGGGTGCTGCCAAATCAGGATTGTTGAGAATATTGTCAATAAAGAAAACTTAAGGGAATTTTTTGTTATGAAATAGATTTTTTGAATTGAAAGTCTCTTATTCATAATCATCTCGCTAATAATTGAGTATCAACACAAATCTTAACTTTATAATCACACGAATCACCTGAGTCATTACCAATTCTTAAATATTGGCTTTTATACTGAATCTTGTTGATGAGCAAAGGTGAAATTGAATGAGTTTCAAAAAACTTTTTCTTGTGGCTTGTGGACTGCTTGTAGCAATAGTAATTAGTATTTTAACCGGTACAAAAGTAATTGCTCAATCCACCACTGATTTAGCTTTAGCTTTATATCATGCTCCTATTCACTATCAAGACACAGACAGCACCAAGTATAGTGGAGACTACATTACACGATTTGATTACGATAACAATTGGCGAGGTACAAATAACTGGGATAACCTAATCCTTTTTCCACTTTCTGCTCATGCTTACTATTCTGTAGCTGAAACTTGTACTCATTGGTTCATTACATATTCCTTTTACCATCCTCAAGATTGGACTGATATTCCTTTCGATCAAGAACACGAAAATGATTTAGAGGGTTTACTTACAATTGTCCGTAAGGACGGTTCAGCTTTTGGGAAATTAGAAGGTGTTGTCACTGTATTTCATAACGATTTCTACTCTTACACTCCAACTGGTAGTCCTTTACGCAATGGTGCAGAAAGTATTGATGGCACACTGACAATGAATAGTTACAGTGGTTCATTGCACCCATTAACAACTCAAGAAGCTAAAGGTCATGGATTAAAAGCTTGGCCTTATGCTGGAAACTTTAAGGGTGCAAGTAGCGAGGATGGGATTATTTACTATCCGAATGGTACTACAGCAGAACTTCCTGCTTCGGGGAATGACCGCGATGTGCAATATCAATTGCTTGATGTGTTTGCTAATAATGGAATGTGGCAACATCAATTAAATGAAGCCTCTTTATCAAGTTCTTCTGCGTTGACTTTTGCTAGTTGGGGAACTTTCAAGGGAGATTCGAGTGGTGGATGTGGCGCTGGTACACCCACTTGCAGTACAAATTCTGCTAATACCCCTTGGGGTTGGGATGATTCAAATGATGGTGCAGTATATAAAGGTGAAATGGCTTTAGACCCTGCTCACCTAACTGATGTTTATTTTGATGGGCTTGGCACTTTTGATACTGCATACATCCGCAACCAATTTATTCAAGGATTGAAAGACAGAGGATATAATTCTGCAAATCTTCCTCAAGGTTGGCCTACTCAGCTCAATCTTAATTCTCTGATTGGCAAGCTCAAAAATCAATGCTCATAACCATAAATAAATTTTATGACTAACGAGATTACGGAAAAAATTAAACAAGCCTCCGATGGTTTGTTAATGATGAGTGAATCAGAGTATCCTTTTGAAGCTTTTTTGTGGTCTAATCAAGCTCAAGAACCAATAACCGCTCAAAAGCTTCTCCAACTAACAGGGCATCCTCAAGATTCGCCAATAGAAGAAGTTGAATTAGAGTATTTTGGCGTTGCATAAATGCGGGATGATTTAATTCAATACGGGTATTTCCCAATACTTTAAATAATGAAGTAATAGACTCATCCGCGAATCATGAAAGCTTACCAGGAGAGAGTTACAAGGATTTGCACGGAAGGAGCGATCGCCATCTGGCTGTACGAGGAAATAAGGGTTTGAAGGCATTGAGAGAGAAAAAAATGGAATTAGAGCAAAAACGTAGAATCAGAATAAATGAATTTACAAATAGCAAATTAAGTACTAAGAGTAACAGAAAATAACCGATTAATTCTTAATCTTACCAGCCCACAAACAGCCAGAATTACCTGATTATATCGATGTCAAGCTAGACGGAATCTATCACTGGCTACTCGAAATATTTTTACCCGACATATCATGTGTTCAACAGCGATTCGGCGTGACGAAAGTTCTTTATTCTCTTGTTTTTGTAATTCCGAGATTTCTGTATTTTTTCGTTTCTTATGAGGGGTGGTAATGGCATCATCTCCTATATAAGCTTTATCGCCGAGAAACTGTTGCGTGTCAGTAAATTTATGGCGGGTTTCTCGAAATAAATTAATATCGCTTGTTTTCCCTAACATTCCGACACGGACATCGACAATATCTTCCCCTCCAGGTAGAACAATAAATTGATTTTTCAGAGTGTGCATTTTTTTCTTGCCAGAGTAGTATCGTTTTTGCTCTTGATAGTCTACAGGTCTTGCTGTAGGTTGTTCAGTGCTATCGACAATTAATTCGTATTCAGACAGCATTCGCTGTAATTCTTGATATTTTTGACTATCTGTTGATACTTCTTCTATTTGAGATGCTGGTAAAATATCTCGCAAAATATCTACCCAATAATTGAAGGCATCATTGGCTTTAGTTTTGGAAATGTTAAACAGCAACCCTAAAATCTCAAAAATTGGTTTTTGTCTCAGGTAAACTAGACATAAGCATATTCCTTCTTTGGCTGACATTTCTGGTTTACGCCCGCCTCCAGGAGCGATAATCCGAATTTTCTTTTTTTCAATTTCTGCCTGTTTTTCTATATGCCTTTGCTCTGCCAGGCCGACCAATGCTAAAAAATGGTCATAACTAATTCCAATTAGGCGTTTAGCTTCATGAGGATACGATTCAATTCTTGCCAAAGGACTTGTCATATTCTTTCCACATAATTGCTACTCCAACTTTTTATTATCTCATGCTATTTATATTAAGGATAAGTCTAATCTATTTCGCTATGAGCTTGGGGAAAGAAGAACAGCATGAATTCTTCAAAATACAGTTGGAGTATCTGTTTCCACGGGCTATCAAATTCTGTCTGCGGATTTCCATTAACCCAGAAATGTTGAATCCTAATACAAAACTTTACATATCTAGTTACACTAACTCTAAAAAGCCTAAAATAGTCAACATGACATCATCTCCTCAAACCAATGAACATAACTGATTTTCTGACACATACAAGATTGTAAATAGCGAAATTTATCTAATAGCGTATGTCCCCATTGTTGTGGGATAGATAATATCTGCAAAAGTAGATAAGCTATTAAACTAACGTAAATTTGTATAGTGATACCATTGACGTTCTTAGTAATTAATTTATCAAGTTTTAAGTGCATCTTTAAAAACTTCCATAACAATTCAACTCCCCAACGTAATCGATAAATATCCCTAATTTCATCATCACTAACGGCAGCCTCTCCATGAGAAGGTAAATTAGTAACTAAGCGAAACTCGGTTTTCGCTTCTAAATCACAAAAGTTAATTACTCTATAGGCTTGAGCATCACCAGATGCACCAACTTTAACCAACCCATTTGAGCCATCAAATTCTAGTTTCCAATTGTTTTTTATCCGTAAAACAAAATATTTGTTTTCTTGTACTAATTCTTGGATAAATTTTAATCCAGCAAAACCCCTATCCATCACCCCAACAGCATTTATTGGTAAACTAGACATCATTTTAGAACCAAATTTATAGTCATGATCATGTCCAAAATTTATGAAGTTATTTGATGGACTTCCAGTAGCTAAATTTAGAGAACTGAAAAGTTTTACTTGATGATGTCCTAATACCCATAACAATTTACTTGTGAGAGTAATAATTGTTGAATCTATTGGACAAATTGCATATTTATCATGCAACTTTTTTTGAACTTTCTTCTGTACTAATTCATTCAATTTTTGGTAAATTTCTTGAAAAGGTTTTTGGCTTCGATGTAAGTTTGCTTTAGAAAAAGTAGAAATATCTACTTCAAATCCTGTGTTGTTTAATCTCTTAAACAAATCTCGCATACTTGTTAAGCTGTTATCCATAGCATAAGAGAGCCAGCACTCAAAGAACAGACGACTGTTCAATACTGGATAATCGTTTTTTGGCAGTCCTCTCAAGATATCTTTGACAATCTTGGGAAATGAATTTATAATCACTATCAAATAGATATACTTTAATCTTCCGCCCAAAATTTAACATATTTTGGGCTGTTTTTATCGGATTTCTCTTAACATTCAACACTTTTGCCATTAACCATGTTGTCAAGCGGTAACTAAAACATTAATATAGTACATTATTACTAGAAAGCTGGAGCCAATTAATTATCATGTTGCAAGTAGTTAGACAAATTAAACAGCGCAGTAAAGTTCAGCTCAAACGGAAAGATATAACATACGAGCTTTGGCGTTTGGATGATGGTGAATTTAGAAAACTTCGGCAAAAAAGCCTTCCCATTAAAGATGACTATATGTTTTATATGCACTTTTATCTTTCCGAACGCGAGAACAAAAATAAACTCAATTTGGCTGAATTATATGTCTGTTTAACGCACTTGTTTGGTGATAGCAGTGATTGGATTGACGATTGGAAAGGTACTTTCTCTTTTCCAGTATTATTGGTTTTAGAAAAAGCACAAGGCAGATTCTTCTATTTAATTAATATTTATGATGATCGGGGTACACTGTATATTAGCTTTTACAGGGTTCTAGAAGCTGAAGTAGAAGGTTATGATACTCAAATATTTCGTGAACCTTTTGAAATAGAATTTTCTCGCCAAGAAATCAACTATTTTATCAGTTATTTTTATGGTTATCTTCAGGGCTGTTTTCAAAGTAGAAGGCTCTTGATACCATCTGAGCAGTTTTTCAAGAAGATTCGTTCTGAGTATATCGTTTATGGCTACAAAGATGAGCATTATTTTGAGGAGAAATACCAATCTCAATCAGAATATCTTGCAGCTATTGAAAGTTTAGAGTCAATTGGTATTAGTTCCATAACTTCGCAAAATGTCAATAATATTTTGCAAAGCATAACTAGCGAAATAATCGGAAATTAATTTATTATACTACAATAATACTACAGTTTTGGCAAATTAGAGACTAATAGATAAAACAAGTAGTTAGACAAATTCGAGAACGTATTAAAGTTGAACTTGAATTAAACAATATTAAATATAGCGGTTCTCAGTTGGGTGCAATATAGTAACAGCAGTGGGTAAACCACCCAATAATGTCTTTTTTAGTCACAGCATTGAACGCATCTGTAATCGCTTGATCTAATTCTTGATAAGTTCTAGCTGCAAGCGAACGCAAAAACTCTTTGACCTTAGACCAACAGTTTTCAATTGGTGAAAAATCAGGAGAGTAAGGAGACAAGTAGACGAGCTTCGCACCAACACCTTCAATAGCTTCTCGGATACCTGCTACTTTATGAGAACTGAAGTTATCCATAACAACAGTTGCGCCAGGCCAGAGATTTGGAACCAAAACTTGAGTGACATAGGTTTGAAATGCTGACGCATTAGTACCGCCAGTAAAAGTCATGGCAGCAATGATACCTTGTGTTGACATGGCTCCAATCATTGTCACATTTTTTCCCCGAGCATTAGGACAATCACCATAAGCACGACTACCTTGAAGCGAACGAGCAAAACGTCTAGTCATAGAAATGTTAACTCCTGCCTCATCGATAAATATCAAGTCCTCTAGCAAAACTGAGCCAATGGTTGTCCAATACTCTGCTCTGAGTTTTTGGACTCGTTCTGTGTATTTTTCGCTCGCGTGCAATGTTTTTTTTGCGTGTCAGATTCAACTTTTGGGTAATTCTGCCCATTGTGGAGCGACTAACTTTGACACCTGTCCGCTCTTTTAACCGTTCACACAACTCCACCAGAATTGCATCATTATCTTCTTTCACCAAAGCAACTACCAGTGCCATCTGTTCACTGCTGAGTTTAGCTGTGTTACCACCTCCATGTGCCTTCGGCTCAACTGTCCCACTACTTCGATATCGCTTCAGTAATTTCTGGATAAAAGTTAAACTCACACTAAATCTTGACGCGAGGTTTCGTTGAGAACCTTCCTGATTTTTATACGCATCAATTACTTTTTGGCGAAGGTCAGTGGAGTATGCTTTCATCCTAGATGCACTTTGCTATGACTTTCATCATCTTCCCACATCTTGTATTTCACTCAAACGAGAACCGCTATATAAACTTTGAAGACTAGACGATGCTGAATACAAACCAAGATGTTGTACTATGTGACATACTCACATTTAATCGTCTTAAATATTACATCTAATACCCTACCTCCAACATCCTGCCCTCACTATCTTTTAGAAAATGATTTTGGTACGCACAAGGCCAAAGTTATTGTTCTTGTTGCCATAAATAAAGACATTGATAGCCATAGTAAATGACTACTATGGAAATACATTGCTGTAATTGCTGATGGAATAAAACCAATTACAGTGGCTTTCAGCATAGCTTGGCGAAGTGTATGACCTTGAGTCAATCCTAGAAAATAACCGTCTAGCGCATAAGCGACTGAGCCAAAACCTAAAACTGGTAACAACCAAGGAATATAAGAACGTAAATTATTGATAATTTCAGTATGATTGGTCAGCAATCTTAACAGTGATTCTGGGGCAAAAATAAATGCAGTAGCAAACATTAATCCGATAACCAAGCTACTGACTACAGAAGTTTGCAATAGTTGTTTTAAAGAAGTAATATTTCCACTACCTTGAAAAATTCCAGCCAAGCTCTCAGTCGCGAATGCCAAGCCATCAATGAAATATGCTGCCAAGCTCACCACTTGCATCAGCAGGGTATTTGCCGCCAGAATTTCAGTTCCTAACATAGAACTAAGGTTGCTAAACATCGCCATTGTCGAAATTAAAGCAAAAGTCCGAATAATAATTTCTCCATTCAGCATGAAAGCTGATTTTAAAGCAGACAGGTCAAATAGTTCCCCAATTAAAGCTTGTATTTGTTTAAATGAAATTGTTTGACAATATAGCAAAATACCTACCATCAGCATCAGATACTGACTAGTGGCTGTCGCTAATCCAGCTCCTCTACTTGACCATCCCCACTGAACAATAAATAGATAATCTAGTAGTACATTTGCACAATTGCTAATAGCTGAAAGCAACAACGCTCTACTACTTTGTGCTTGCCCAAGAAACCAACCTATCAAGACAAAGTTAATCAATGTTGCTGGGGCACCCCATACTAAAGCATTATAGAAATCGACTCCAGAACTTTTAACTTCTGGTGTAGCACTTAGAATAGCAAACCCTAATATTTGTAAAGGTTGCTGAAATATCAGAATGGCGAGTCCTAATATCAGTGCTAAAATTCCATGCTGTAAACCAATCAGTACTGCCGATTGGTTATCTTTACGCCCTATAGCCTGTGCAACCATTCCAGTTGTACCCATGCGTAAAAATCCGAATGTCCAATAAATATAATTGAATAAAATTGTTGCTATTGCCACACCTGCTAAATGACGAATCTCCGTTAAATGTCCTAAAAACATTACATCTATTAGTCCTGCCAACGGAACCATTAGATTTGAAAGAACATTTACAGATGCAAGTTTGAGAAAATGGCGGATGAATACTGAATGTTGAGCAAAGATAGACATTTACCAAACCTTTATTTCTATGTCACAACAGCCTATGACATTCTTAGACACTGTGGTGTAGAACTTGGCAAAGGAGACTTTCTTGGTCAGCCTTAATCAGAGCAATATCTAACGCAATTTTTTCGAGATTTTCCGATCTTGCTTGGGTTAGTAAAAAATAGACTTTTTCACTTCTTGGCATTGTGGGGAAAAGTTTTTTCTTCAATATTTCCCTTTTCTCTTTCTCAGCAATTACACTGGCTTGAATTTGCCGATTAATTAGTAAAATATAATACTACATTAAATTCGATATTTGTTCGGTTATGAGTATGATTTCCTTTAGACCAATGATATTGATTATAGGCATAAGTATTGGTTTACTGCCTCTGTTGTCCAATTGGCAAGTCCTTGCACAAAATCAATCACAAAACATTGAGCTAAAAGTTTATAGTGAAAACGAGCAAAAACAAAGCTGTCCAGACAAAGTGATTGTCACTGAAAAACCTCATCCTTATCAAGAAGGCAGTTTTTCAACAGATGGCTCTGTTAACCTGAGTGCCTACGCCAGTAACATCTCTGTTCAAGCCAGTAATAGCTTCAGCGTTACATGGGTTGGTACACTTAAGCCGAGATATTCTAAATGCTTTGCTTCTGCTGGAATGACTAAGGTTGATGGACAAGCCTACTCTGAACACCTTAATTATTTACGGATGCACTTCGTTAAAGGTAAGGTTTACTTCATCTTAGATTTGGCTGGTGGCTCCGATCCAAATAATTATCCTCTAGTCGTGCTAAACAACAGTTTCAAGAATGGCAATCCTGCCTGGACTTGGGGCGGAAGTGACTAAAGGTCATACTGGCACCATCCCAGATGTCTATTAGAAGTATTCCAAGAGCAAAAGTCTGTTGCGCCGTCTGCTGTTGTGAAAGTTCCACCCGACCCAACTTCCCCTGAAAAGAGCCAAGTAAAAATACTCAGTCCTCAATCGCCTCAATACCAAGTTGCTTCAGTCGCTCAAGGTTATCCTTCATAGTCTTGATCGCTTCTGGAGAGTGCCCCTGCCAATCCATGACCTCGCCCATAACCCGCAGAGGCTCCCGTGAGCGGTATGACTTCGTTGGATTACCTGGGAATTTCTTGTCCGTCACATTGGGGTCATCCTCGATCGGCCCGATCGGTTCCACGATGTAGATTCTGCCGCGTCCCTCGCCGAGAGCTAGTTCAGCCCCCCAGGTTGCCGCATCAAAAGTGGCAGCCAGATAAACGTAGGTCGCCTTCTTCCTCTGACCGTAGTTAGAGTGATAACCGGGTTCGATTAGGTCTCCTGGCTTCAGGTCTGCCCGTGTCCCATGATAAAGAGTCAACTCCGTGACCGTTCCCGTTACCCACAACGGCTCGCGGGAGCGGTATGACATCGACAGATGCTTCGGAGACTTCTGCTTTGTGAGTTCGGGGACATTTTCAATCTGACCGAGCGGCTCTACGATGTAGACTTTGCCATGACCCTCGCCGAGAGCTAGCTCTGCCCCCCAGATAGCCGCATCCAGGTTGGGGGTTAGGTAAACATAGGTTGCCATCCTATCCCGCTCACCCACATCCGGGGGATTGCAGGACTCGATCAGGTCTCCTAGCTTCAGGTCTGCCTTTGTACCGTGGTAGAACTGCTGCGAACTCAGATCGTTGAACCCTGCCATCAGCTTGCTCCTTTTACTGTTCGACTGCATTGAAATCACGGGATAGTTATAACCTTTGCTGCAAAACCTACTAACTTGGTGTTCGTCAAAGGCGTGCCGAACGCGAGTGCATTCCGCAGGAAAGGCGTTGCCTCTCGTTCACGAAGTGTCTCCGATAGGAGAAGAGAAGGTATCGCCCTTACCTCAAAACGAAAAATTACCCAGCTATATCCTTCCCACTCTTGTAAGTCATAGCTCTGGGTTTCCTCTTGCCTATAGGGACTACTGATTTCTTGGGTGCTTGTGGCGGACGGCATTTCTCACAGTAGAGCGGTCGCACACCAAACGTTTCTCTTTGGGTGGGTTGCTCACACTGCTTACATACGAAGTTGAAAACGCGAGTGTGAATTTCCCGCTTGTGCGCTCTAACGGTGTACTCTCGGACATCAATTGTTTTGCTGGGCATCGGTTCTATAATCGCTGTTCTATTTATAAGGATAGTTTCTGGGCATCAATATATTCATGCACCATTTGATTGAAACAGTAACAATCTGATGGTTTTTCGCCGGGGATTAAGCAGAGGCGATGCCGCCGGAAAGTGCGAATACGCGATCGCACTCCTGACAACCGCAATTGGAGGCATCTGTAACAGCAGTGGCGACTGCTTTTAGTCTTTGAAGTAGCGAATTCGACTTATATAAATGAAACTAGAGTTCAATAACCCTTAGTTAGTCCTAATTAAGAAGATAGTCTTTAATCTTGTTTTGATGAGAGCGCAAAATTTTTAAAGCAAGATGTTCACTCTTACGAATTGTCTCTCGACTAAGATTTAGGCGTTTTGCAACTTGACTCAAGGTTAGTTGCTGATTATCTTCCAATCCAAAACGTAGAGTCAATACTTCTCGTTGCCTTGGATTGAGCAATGCCAGCAACTTACTCAAGTCTTGATGTAAAAGCTCTTGAGCTATTTGCTCATCTAGGGAAATACCATCCATCGGTAAAATATCAGCTAGTTCAGTTTCACGCTCATCCCCAACTCGCATTTCTAGCGACACTGGAGCGCGGGAAACGTGAAGATATTCCCGTATTTGATTGGGTAATAGATTTAAGGATTCGGCAATTTCTGCTACAACTGGAGGACGACCTAAAGATTGAGACAGTTGCTGCTGTACTCTCCTGATTTTGTTTAATTTCTCATTGATATGGATTGGCAGACGGATAGTGCGAGACTTTTCTCCGATCGCGCGTGTTATTGACTGCTTAATCCACCAGTAAACGTAGGTTGATAGTTTATAGCCTCGGTTGGGATCAAACTTTTCGATTCCCTTTTGCAAACCCAGTGCCCCTTCTTGGAGCAAATCGAGAAAATCTAAATTGTGGTTCTGGTATTTTTTGGCAACAGAAACCACCAGCCGTAGGTTAGCTGTCACCATTTTCTCTTTAGCTTTTTGACCTTGTTGAATGATTGACTGTACTTCAGCTTCAGTTTGCCCAAGCGAGGTAGCTAATTCTCTTGTGGTTGGTTCTCGGTTTAATTGAACTGCGAGACTTGCACGCTGTTCTTCAATAGCCATCATCTGCTGCACAAGCCTAGCATTTGTAATTTCTTGCTCAGGAGTTAGCAGAGGGTAGCGTCCGATTTCTTTGAGGTAGGAGTGAACTAAGTCCGTAGTTGGGCTGGGCATACTTTCAATTAATTGTGACGAATACTTTTATTTCTCATTTGGATAAAATATTTTAGTAAGGATTCAGGAGTAAGAATTCAGCTATTCTGAATAGTTAAAGAATCAAATAAAGACTTGATAAATAAATATCCTAGTTTTAATAAAATAATAATTTTAGGTAAAAGATAAGCTCTAAGCTATTCAAGGTTATCTCTTATGGCGCAGAACTTACACCTAATAGAAAAGTGCCAGCTTAAATAATTTTACAGCTTCAGCTAAACAAGCGCTTGTATTCTGTCTTAACTATGTTACTGCCAATAAGATTCAGGCATATTGATCGATATTGTTACTTTTTTATCAGCCAAACAATTTTATATTTCTATTTCAAAAATCATTAAATCTGTCGAAATTTGATTAATCTAAATACAATGCTGAACTTTGAAATGCCTCTTCTGGTGTTCCATAAAAAGTACCATTGTTAAATACGCTAGGTTCGTACTTTTCATTACTATAAGTATAAAAAGCCTTTGTCCATTTCTCTTCATTCCCTTTGTACCGCAATCGACACAGATGAATTGGTGTATTTTTGGCTCTCTCTATATATTCAGAGCGTGTTATTTTAAACATTGATAGGTCATCATTGTCTGGTAAAAATGGTTCTTTATAAGCATCTATGTAACAGAAATATCCCTTAAAACGCACATCAATACGTATGTATTTTCCTGCATAATGCTGCTCTGCATAAGCTAATATCCGGTGCTTTGTTCTCTGTTTGACCTGCTCCGGTATTTTTACTCCTCCTGAATGTGGATCGTTTACCCATCCTTTCATGATTAGCTCCTTGGGAATACTGAGGCTGATATTACACTGCAACGGCAGAGATTACAAATCTGAACTTTTTGCAATTCTTATCATTACCTCCGAGGTAAAAGCGGAAACATCTACTATTTGTTGCGGCTCGCAAACATAAACGCTCCGGCTTGCAAACAAGAAAATTGTTGGCTCACATTAATTGCAAATAAGATTACACTTCGGCTCACATTAATTGCAAACAGACTCATTATTATTTGCAACGGGCTTGCAATCATCCGACTTGGCTCAAATTAATTGCAAATAAGCCAGATGCAGATAAAGCGGTGGGTATGCTTGTCTGCAAGAGTATCGAGATGAAAAAGATTTAATGTACTAAATATGACCAATAATTAAAGTGGCAACCCCGCAGCTAGCATTTGCTCTTGTAATTCACGCGCACGAGTGGGATCAAGTTGTCCGCGAAACAGCGATTTAATTTCAGCCGGCTTGGCATTGAACTGTTCCGCCAAGCCCCTCACGTCATAGCCATGCCTTGTGAGAGTGGGTTCCAAATCGTCAATTTGCTTTGACAGAACTGACTCCACAATCACCGTAGTCACAGGTTTGACCGCGACTCGGTACGCCGCCTCCAAAGCTAGTGTCAAATGTTGCTCAATTTGTAGTGGTGTCAAGAGCCGCGTGGCAAGTAATTCAATAGCTTCCGCCTCCAATATTTCACCAATTGGAGTATCAGAGATAGTGCATTCAGATACTAGCCATTCAATATATTCTCGCTGATTGCCAACAATGCCTTCCAAGGAGAAGACTGTTGCTCGATAACCGATTTCTTCCATAGTCGGACGGCGCAGATCATTTTTCAGTTTGGGATGACCAGCCAGCACCACTGAAAGTGTGCCACCACCGTCTTCAACTACTTCGATTAAACGTTTGAGTCCCGTCAGGGTACTGTAATGAAGGTCATGAGCCTCATCAACAAACAGTGCTACTGACTTTTTACCTTTTCTAATCAGGTCGCGTAGTTCCCGTTCCCGTTTTTCACCGTCTTTAGGGATTTTAATTTCCTTATCTGTGGATAAATCGTAGAATAAAGCAGCAATAAGTGTTGGCAGTGTCGCCCGTTCTTTATCTACAGAAAGGGACTTCGAGACTAGAATCTTACCTTCTTTCTCCAAAACATCAAACAAGCGTCGTAAAGTAGTCGTCTTGCCACACCCAATAATTCCCGTTATGGCAATCAGTTTCCCTGAATGGATGGCAGCTTTAATGTCTTTGAACATTTGCTTTTGATGGTCTGTTTCGTAGTAACCAGCCTTGGGAAATTCCTTGACCAAACGAAAGTGTTCCATTACTTCAGTGAGCATTTTGCTGCCCTCCTTTGTTCGAGTGGAAATACTGCCGTACTCGTTCAATAATCACTTTTTTATTCAAAGTCTCAGCTAGCAGCCCATCAATAAAGGCAATTTGTTCAGTGGATAATTTCGCCAAAGGTTTAGCGAGATAATCTGAAATCGCCAGTTTAGCGAATAATACAGTGGGATAAGTAAATTCTTGGAACGGGTCTGGGTCTTTAAAAGGTGTGACAGTTGGCTCAATTTCCTTGTACTTATCCACCAAAAATTGCAGATCCGCGTTTTTATCCAAGGCAGTTCGTGGCAAGCCCAGCTTAAGAGCTAAATCTGCAATCCGGTCTGCCCGTTCTTCGGTTTTAGTTTTCTTGTGTTTGCGATAGCGATGCAAGGGGATAGGCCCATCAACTGGGTAAAATGGGCCATAGCGTTGGTCGCCTTTCTCTACATATAATTCGTTATCAAAAAGACCCCACCACAGCACCACAGTTTCGCCTGCTAAGTCTGGGTTTACTTCATAAGCCACGCCCTCAACTGATACTCTGGCTGTTGCATCCACTTTCCTTCGTTGCGGTTCGCGGGCAAAAGTACAAAATCGTTCCCAACTACACATCTGCCTGATTCCGCTTTTTGGCAGATTTCGCAACCAATCCTCTAAGCGTGAGTGCGCTTCTGTACGGTGTTTTTGGTCGTTATAATTTAGCAGATACTGCCGTAGCCATAGGTTAGCCTCAACTTCGTTTTCTGGTTCGTGAAAATGATACAGAGTCTCATGGGCTTCTTTGACTGTCCGGAACGGTCTTTCCACTTTTCCTTTGGAGCGAGCCGTTACCCTTCTCCCATCTTTACCCGCAGGCAGATGGCTAGCAAGCTTGATTCCCAGGCAGTCCATCACATTTTGAAATACATGGCTTTTGGCAATTGGCCCGTTGTCCGTATAGATCATCTCAGGAATTCCCTGGAAGGGGCATCCATCCGAGGTGGAAGCCGTCATTGCATTAAATAGGAAGCGCAACGCTGCTGTTACATCCTCTCCATAAACACAATGGTATTCCTGGTAACACACACCACTGCGGTCATCAACGACACTATAAAGCATCAATAGCGGATTCCCTTTACCCGTTTCCACCCATAAGGGCTGCTTTACGTGTTTTAAATCGGACGGGCTAAGGTCGAAATGCCAACATTCATTACTGTGAGTTGCTTGAAAACGTACCGCAGGCGGTTGACGAGTCATTGTGAGATGGTCGTAGCCCCATGTTTTCAAATAACGGTTGACAGTGGCTTTAGTTAACAACCCCTTGGGTGGTTTGATAAAACCTTGTGGGGTGTTCATCCCGAAATCTTCTAAAAGTTCAATCGCCCGTGCAGTGGAGACGTGCCGCCCTTTCTTGTTGCAAGTGCGGATTTTCGTTGCTGCAATGACTTCACAGTAAAGTTCCATTTCCGCCTGTGATAGCTTTCGAGGTGTCCCGCTATCTGAACGGTTGATCGATTTGGGGCGTGATGAGTTACGCAAAGCACGATATAGAGTATCAATAGACACTCCATACAATGAAGCTGTTTCTTCCATGAGTTGCCGACGTTCTTGGCAACGGCTTGGTAACATATCAAGTCGATGACGCAAGTTGGTTAAAGCTTCTGCTGGAATTTTCTTGCGGATCATGCTCGCCTGTATGTTCGCCTCATGTACTGTCCTTATCTTTAAGTTTGTAGCAGAAAACTGACCACAGAAATTACATTCTGTTGCCAGTTAGGTGAAAAAGTATAACAATTTGAGATAGATTAGCTTCAAATGAGGCTTGAAAACTCACCACAGAAATTTTTGAAGGAAGTTTGGTGCTGTGGATACACTTTACTTATCTGAAGCCGAAGCACTACTCATAGAGTATGAGGCGTTCCTAAAAGGTAAAACGCATAGCACTATTGATGCCTATATGCGTATCATTAGGCAGCTTCTTCTTTGGATTGTAGAACATCCTGGGAGTGGAGGAGATTTTCAACCCGAACAGTTGACCAAAACGGCGATGGAAATTTATCTCGCCTATCTAGATACGTCAGGTTACAGCATTGCTCACCAAGCACGGGTTAAATCTGCTGTCAGTGGTTTTGCCCGTTGGCTCATTGAGGAGAAGGGAATTTTACGTCGCAACCCCACCAGAGGATTAAACATTCCAGCCCAGCCACTTTTAGCCCCCAGACAATTGACTCCTGACCAACGTTATATTTTACGCAACCTGATCGAAAAAGATGGTCATCCACGTAGCATGGCTGTGTTTGCATTGGGGTACTGGGCTGGTTGTCGCGTGAGTGATGTTTCCTGGCTACGGATAGAGCATACCCATATTGGCCCCAAAGTTGGCTGGTTGCACGTTGGTTACAAGGGTGGTAAGGCGCGAGATATTGATCTAATTAACGCTGTCCGAAAACCAATGTATGAATATATTCATCACGGCGGGCGAGATACTGAGAGTGATTACACTTTTACCTCTCAGCGCAATGAGAGGCTGACCGAAGCCGGCATTCATCGCTGGTGGAAAAACATTAAAGCACAAGCAACTGTTTCTGAGTGGGAACTCATCCATGATGTAACTTTTCATGATCTGCGTCATGATTTCGCTCACCGAGCGCGTGAAGCAGGATGGACTTTGGAGGAGGTTGCTTATTATCTTGGTCATATCACCAAAAAGGGAACTCCAGCTATTCAAACCACGGTTCGGTACACTCAAAGTAGCCGACAGCAAGTGAAAGACAAGCTTGCATTACTCAAGGGATAAAGGAGAGATAGCAACGCCCAAAGGATTTTATATTGCTCTATCCAACAGTTGCTGAGCAGGCATTCGGCTTATTTGCAATTAATGTGAGCCAAGTCGGATGATTGCAAGCCCATTGCAAATAATAATGAGTCTGTTTGCAATTAATGTGAGCCGAAGTCCAATCTGATTTGCAACTAATGTGAGCCAAGAATTTTCTTGTTTGCAAGCCGGAGCGTTTATGTTTGCGAGCCGCAACAACTATTGTAGTATCGCAACTTTCAGATGCAGCAGAACCCCAACTCGTAGAAAATGCTGAAGATGTGGCTCAACCAATGGAAAATTTCCTGGGTAGTGACGACATCTTAAACTCACTCAAAACCAAGAGGATCGGGTGATAGTAACCTATAGCCTTATTCTGGAATATCAAATGGCAATATTTATACACTAACATTAACTAAATCAACATCAGCAAGCCATATTGTTCTACTTTGGGCAGACATTTCTTCTAAAGTTGGGGAGCGCCACTCTACCCCATAAAGCCAATTATCTTTGAGACTAAAAATTCCTTGAATAATACGGCGTGTCGGCCGTTCACCGAAATCAACCTCAACTATGTCCCCCAATCTAAAAGCTGGAGTAGAAACAGTGGACTTTTTTAGTACATTTGTTGTATAAAATTCTTGTTCAGCTAAGTAGAGAGTTTCATTCTGGCAAACAATTGCATAAATCCATTCCTGTTTTTCCCACAAAACACCACAGCAGTAGCCTGATAAGTCTGAGATTGGCAACAAAACTTTTTCTAACATTCTTACTGCTACTGGAGGCATAGTCTGACCCCACTCAGGAGAAATATGCCAACAGGATTCTAAAGCGGTAATTTGGTTAATCATCTGGGAATATAGTTCTCTTTTTTATACATACACTCACTTGCTTCAGTCTGATCCGGAATATAATTTAAATTTCGGGAAGCTAACGCAACAGATGGGAATTCAAACCCAATCAATTCGAGAGCCTCCCAATTTGAGAAGACTTTACTGATACACTAATTCGTAACTAAGATAAAATTATTTTGGCAGTAGCGATTGCCTGCTCCACACTCTCCACAATATAAACATTTTCTGGCGACAGTTTTTTAAAGAAAAGTTTACTTTCTTGATCATTATTCAACAAAATTACTTGCTTATTTGCTTTCAAAGCTAGAGCAATTTCTGAAGCGGTTCCTGCACCCATTCCGCAAGCAATTATCACATCACTGGTAAGAACGTTAATATTGTTTCTAGAATTACCCATGTCTGTGAAAATAGCAATATCCACCCAAGAGGACATACCATCCTGATTTCCACCTGGAAGAATACCAATAGTTAAACCATCAGCAGATTTTGCACCTTTGCTTACTGCATCCATTACCCCTACATTTCTACCACCAGTGAGTAAAACCCATCCTTGTTTGGCAATAAATTGACCTAATATATAAGCATCTTGTAAATCATTTGCTGTCGCATTTTCTCCTCTCCCCATAACCCCAATAATAATTCTTCGCATAAAATTTCAGATGATACTGGTTTTGGGCAAAAAGTCAAAGCTTTCTCCATAAAAGGGCAATTGGCTGAGGCGTTAGGAAGATAGCAATCGCCCTCTTTTGGCAGTGAAGCGCCTTTGCCTCACTTTAGTAGTTTTTTGCCTGCTCATCCAAAAAACACCATAACCACTGTTCTCCTAACTCAGCCGAGCTAATTACTGAATGTCCAGTTTCCTCGTAATGCCGTCGGGCATGTTGATGAACAGAAGAATCACAGCACAGCATCTTGCCGCAACTTTGACAAATACGGAGATGCACCCAGCGACTGTTTATTAGGATACATTCTTCACAACGAAATACTGGGTAGTTTGCTTTAGAAATCAGAGTCTCTGTAGTTAGATTGTCTAAATGTTCGCAACTCATAGGAATTTGAATGACACGTTAATCAGAGTATAGATTAGTGCAGAGAAACTTCTATTTAATACAGTGATGGCTGCGCCAACGCCTGCCAGAGAATGCCCGAATGTGAACAGCGCCTCTTTTTTTAAGAAGGGCTGTAAGTCAACGCTACAGCTTTGCAATACAACCAAATTTTTAATTAAACATCAATATTCATCTGTTCTATCTGTCTAGCAGCTTTATCCCACAGCTTTGCAGAAGCCTCATCTTTCCAATGATTTCTGAGATTTTCTGCTTTTTTATGACTGATTCGTTCTAACATTTCTAGAACTGCGGCTAATGTTAATTGATCAACAATTGCCTCTAAAGACTCCATATATTCTTTTGTCATAACTAACCTCTTGAATAACTTTTAACATTATTTCCTAATTTTACATATTTAGATAGGTAATCTATATTGTTATATTTCACAATTATATTAGATAACAAATGCCAACGAAAGTTACAGTCAAAGTTTTGCTGAAGGCTTACGTTTGTCTATCCTTACTACCAGCAGAGTTAAAAGCGATGCCTGCGGCGAGCTATGCCGGAGCAGATAATCCTACTAACCCAATTATAATGAAGTTTTGAAACAACATAACTTGCTAAAAAGAATCGACCATATTTACCTGTCAGTATCTAATTTTTCTCAATCTGAGACATTCTACGACTTGGTAATGCGAGAACTCGGACAACACAAGGGCGATAAAGTTATTGCTGAAGAACCACACGCTCATTACTTCGGCCCGCAATTTCAGTTAACGATTCAACCTGCAAGGTCAGCACAAAAACACGATCCTTATGCTCCTGGTTTGCATCATCTCTGCTTTCAGGTAGAGACAATGACTGACGTAGATTTATGCTTTAAGAAACTCAGATCAGTAGGAATCAATGTTAGCCAACCCAAACGATATCCCGAATATCATCCTGAGTATTACGCAATATTTTTTGATGATCCAGACGGAATCAGATTGGAAATCGTCGCTAAAACATCTACTCGTCAAGCATTAGAGTTGCGGTGGGACGAATTGAAAGAATTTCTTAATCCTCTGCAAACATTGCCTAATACTGAGTTTCATAACGCCTAATAAAGTTTAGCGCCTACCATTACCCACGCTGTCTGAAAAACAGCAATTGCTACAGCTTTATAGTGATCGCTCCCTAATAGTAAAGCAATTCATCTATGGCGCTACTTTTTCTTTAAACTGTTTCCCAGCAGAGAATGCAGGCACTTTAGTCGCTGGGATAGTCATTGGCTCATTGGTTTTCGGATTACGCCCTTCGCGTTCTGAGCGTTCGCGTCGCTCGAATGACCCAAACCCGACGAGCGTTACCTTTTCACCATTAGCTACAGCCTAGGCTGTTGACTCTGTGCCTTTTTGGAGAGTAAAAGTTCATGCTGTTTCTGTGTCATTAATTTGGGTTGAGTATAAAGTTTTTCTCTTTGAGAGCATAGACTGTCCAAAAACCTCCGCAAGCCACTCTTCGACATCGAAAAAACTAATAGATTCAAGTGCATTTTTCACAACGGTAGTCGTTAAATTCATAGTAGATAAACAAATGGTTAACAACATTTGCCCCATTTCTTTAATTGGACACCGAGCAGAAAATTGTTTATATTTTCCAAACAAAGATTCAATGATATCAGAAGTGGCTAAAAAAGTTTGTTTATCCTTAATTTGCGAACACTCATTAGTCACGTAATCAAATATCTGCTGTTGAAAATATTGGAGCGAATCATTCACCAAATCAGATTGATTTTGCTGAAAATATTGCAGAGTTTGAGAATTAAGTCCTAATTGTTTTAATTGGGTTTCTAGGCGGCGCGTCATTGTCACCATTTGATTCCAATGAATCAAGTCTGTTTCATAATCAGCTAACCATGCCAACTTCTCTACTATTTTTGAAAGAATCAGCTTATGTTCAATGTCTGGCATTAATTGAATCAGAGTCTCTACCGGAGAGTTTAATAACTTAATTGCCCAATTAGTCAGTCTTTCAACATTAAAATAGCGACATTGAGAACGTTGTGATGGAGGAGATAAAAAAGATAATTCTGTTTGCTGGAGTTTTTGCCTGCATCTGTGACATTTTTGCAGAAATGACTGATATCTATCATTCGCATCTAACTTATATTTTAAAAGCAAAGCCATTGCATGAGTAACATCATGAGTGTAAATAATTTCTGGATGATTCTCTTGATATAGCTTGATTCCACGCGCTAAGTCACTACTATGATCTGCGACTATTTGTACTGGTACACCAACTAGCTCAGTTATTTTCTCTAGCTGATGAAGAATCATTTCTCCTTTTGTCGAACCCATAATTTCTAATCCTAATAGTTCGACATCTTCATGTGATAAAGCTCGTCTTTTAGAAACTACTTGTTCGCTCAAATGCTCCTGTGAAACTCCTAATACAACTAAAGCTTTTTGCTTTCCAAGTTCGAGTGTAAAATCAACAATAAATATCCAATCATCCCGATATTCTTTTTTTCTTGTCAATTCATATATCCCCATCCTCCCTAACCATTTTCTTATACAAGTAAAGCTTGGGGTTATCTTTGATTCAGAATTAAATAACTCGAATACTTTTTCTGCTGCTCTAAAACTGATGCCACAGTCAATTAAAAGTTCTAAAGCTTGTTGAATCGTCTGAGCATCATAAGTATGTCCCTTGATACTTAGTTCATCACTATATTTGTTATCATCTAAGTTGATGTCCTCGCTAACATTTTCTTCTTTTTTTCACTGACTCCTCCTATTCTCTGCTCTTTTATCTCTGATTCTGCTGCCAGCGCTCTCTGTTTCCAATACTCTCGTGACGCAGTTAAATCTCGGACTTTTATTTCTAATGCTCTCACTTTTTTTTGTTTCTCTAACGCTTTTTCTCTCCAGCTATCTCGACCTTTCTGAAACAACCGTACTAATCTACTAACTGGGCTTTTAAACTCTTGCATTTGCTTTAACTTTTCTCGACTTCAACAACATCATTATTGCATGAAATAATTTTGCCTTAAAACCAACAAAGTCAACAGCCTAGCTACAGCCTCGGTAACAACTGACAAAAAAGCACTAATGATTTCATCAGCTTGCTTTTTTGTGATGTTGGTCTTTGATGCTACAGCATCCACTAGTTCGCCTTTGTTCATAAATCACCCTGAAACATTGCCAGTATTGGAAATTTACTTTACCATTACTACCTTTTGTGAGGATAGGGGGAAAAGGACTAACAATCAAGAGCATACGAAAATTAACAATGCACTGCTACTGCTGATTAGACAGTCCAACGCCATCACAAAACCGCACAGCTCCCTTGTTTCATCACCTTTGTCGCGTAGAATAAATGTGGGTATAGCCGAGCGCAACACCAAAGATATTTACAAAGAAAAAGTTTATGCGCTCCTTTGCTCCCGATTTGACAAGATCCAAACAGCATTGGTGATTGAAACTAACACATGAACTCTTTAATTTAATTAACGCCGACGCTTCACAAGCATGAATAGAGCGATCGCACTTCGAGAGTTAAAAGATATCTTAAAAAGTAATTTAGGCAGGAATGATTAAAGCAATTAGTGAACGCTTATCAAGTGATTGAACTTTTCCTACAGAGTTGAGATCAGTTACCACCCGGTCTAGTAGTTCTCCAGCTTGGTCACGATATTGATGTTCCCGACCTCGTAAACGAACAGCAAACTTTACCGAATCGCCTTTACTCAACCACCCAACTGCTTGTTCAATGCGTAACTTATAATCAGCTACACCTATATTCAAACCAAACCGAACTTCTTTTACTACTGGTCTAGCACTTTGTGCCTGACGCTTTTTCTTTTGATACTGAAGCTTGCCATAATTCAAAATCTTTGCAACTGGAGCCTCTTTTCCTTCAGACACTAATACTAGGTCTAACTCTAGGCTTTCGGCTAGCTGTAATGCTTCATTGATATCGGTCAAACCACGATTATTATTCTCATGGTCAATCAAGAAAACTTGGGGTGACTTGATTTGCGAGTTTATTAGTTGTTTTGGAATTGCGATAACGTTTGACTCCCATATATTACAAATCTATAGAGTGTTACCCATGCCAACTATTAACAGCCTTGTTGTATAAATTTATCGTAACCTAATCCTTTGCTCCTCTTTTTTACAGAACCTGCATAATATGAGCGCTTCTATTAGGAATTTTCTATATGCTTTGGCATTGATTCATCCTATTGTCACCTTTTAAGAGGAACTTGTGTGAAGCTGTAAGAGAATGAAGAATCAAATTTTCTTCTCTAATCAGTTTTAACTTACATAATTGTGAATATGCCTTCGATTTCCTACAACCGCACCGATAGCCAGCAACCGCAAAGCATTACCGTTGAAGGTTATGTTGTCCGTCCTGGATTACACATTCTCACTTACGAGCAACTCAAGTTGCTACGGGAGCAAACACAACATCATTCTCAGCTTGAACATTTAGTTAGCCAAGGTGTGATTAAGTTGACTGGTTAATAGTCGCCAGCACAAAAATTCTAACTCGCTACATCTAATTCCACAGTTGCTGGCTGTTGTTCTTCCTTTACAGCACCCAGTGACTCAATAAAAGCGTCAATTGCCTTGGCTGCTGACTGCTTACCTGTTTTCAATTTAGAAAGGATATTTTCGCGTATTGCTGAATAATCTGGTAAGACTTGCTGCTCAACGGAAACAGCCTCTTGTGTTTGTAGGGCAACTTCACCCGAACCCTTCTCTATTAAGCCTTTTATCTGAGCGATCGCTTGGGCTAATTCCTGCCTAATCACCTGTTTTATCTCTTCCCCATCAGGTGTAGACGCAGCTAAAGCATTAACTTCTTGCTTAACTATTTCCTTAATCTCATCACCATTAGATAACGCTAGCCCAGCTTTTGTCTGACCCAGGATTCCCTGAAGCAATCTTGTAGCTGTGTGATTTAATGACTCATTTTCCGAAATCTGCATTGCCGATAAAGCTTTGACTTCTGCATCAGTTAGCCCAATAGAAATTGTCACCTTAGCCATACTTTTGATACCTGTAAATATTAATCTCGTGCATTGCTAGTTCTGTGTTTCACCGTCTGTATAAACAACTTATCAACGGCGTAATTATTAAACTTTGCTCTGTGAGCAACTTCTACCTCGATTTTTTAATCTAGCTTCAACTTAATCAAGTTGCATTACTTCAATTCTACCGCACTCCTAGCTGAACATTTATCAGCTAGGGGGTACATCTGCATCCATTTAAACTATTGATTTTTAAATGTTGTCTTACTTCTAATACCCTTGCAGTTTTACACTCTGTAAAGTGTGTTGTTTCAATACCTGCTTTCCATCATCGCTAGCCCTGCGATATTACCAATTCGACAGTAAAGAAAATTATTGGTACAAATGTATTATATATGAGAGTAAGTTGAGCTATGCACCTTTTGTGGTTTCGTCGAGATTTGCGTTTAACTGATAACGAAATTGTCACCTCTTCATCTCACCCTGAATAAACTGTTAGTGTTTTTGGGGTATCTGCGATCGCAATTCCAACTCCCCAACCCAAAAACACAGCAGTAATTGCACCAGAGATTTGCCGCATTTGATGTGAAATTATTAATTAGCCTCGGATTCCAGATTCAGAATTACAGGTCAATTCATCTGACCAATTTTTGTCAATATTAATCACCTGTAAAGGATTAACCCTTGATTTTGGTAAGGATAGGTTACGCCGAAGTACTGTGCAAGTTAAATTTAGAACATCCAAAGGTTAAGAAAACTTGCTTATATCTTTTACTCAGCACCATTGACCATTGATGGGCAAGAAACAAGGTCTTTGAGTAAGCTGTTACGCAAATAAGATTGCATATCAACTGGTGAGGTTGTCCTTTGTCATTAGTCATTTGTCCTTGCTAAACACAAATGACTAATGACGGTCTACACGGGGTTTGTGCAATATGTAGGCGCGTTAACTTAATTTAAGGTGAGTTCGGCAAACCTCTCACTGCCTGAAGTAAAGTTCAAATCTGTCCCTCTCCGGCTCGGAGAGGGACGATTTTGCGTAGTAAAATCAGGGAGAGGTATTTGTGATTGAGCTTCAGCAAAGACTTTGGGTTAGAAAGTAAAAGTAGTACGTACTACTCCCACATAGATATTAGAGTTGTTGCTATTACCTTCAGGATTCAAGATGGTGATTAATCCTGGTGTAATAGCAATGTTGTCATTCAGCTTATATCTATAGAAAGCCTCTAAATGATAGGAGATATTATCGTCTTGGCGACGATTATTACCATTGACGAATTGATTGTCAGCAACGTAAGGCGGTACACCAAACACAATACCGCCAAAATTTCCTTCCCTACCCAAATCAGGGAAGCCTAGCTGAATGGCCCAGTTCCAAATTTCTGCATTACTCCTAGCAACGGCTGTATTCTCAGCTTGGGCATTGGCGTAGCTGCCCCAAGCAGTGATAGTAAACTTAGGACTAAGTTTGTAATTTCCAGTCACACTATAGTTATTTACAGAAGTTCGCGCCCCGTTGAATGGGTTGTTGGCAAAACCAGTACCAGTGCTACCAGTAACTCCGCTACCATCAGTATAATAGGCGTTGACATAAGTAAAAGCCAAACTTAATTCTGAGGTTGGTTGGAAGGTCAGTTGACCTAATGCAGAGTAACTACCATTAAAAATGCCTCTACCGTTAGCGGGGTCATTACCAACACCCGATGGCACAACGTAACCAGCAGTTAAGGTGAGAGCATCATTGAACTTTTGATTAATGATGATACCTGGCCCTTCTGCTGCTCGATAAATTGGGTTATAACGCCCAAAACGAGATAGCGCACCTGAACCACTAGAATCGAAGTTCCGACTGAGAACAGGTACTTCATCAATGTATTCCAACCCTTCAGTTGCGATGTTGAAGGTTGTGGAGTTGCCTACAGGGAAACGGTAAAACAGAGCTGATACACTGACATTGTTGGATTCATTGCCATCAAACCCTAAACGAGTTTGGTTAGTACCAGTCACTGCTGTATTGAATGAAGTGATGTTTCTCGCTTGTAACCTAACTCTGAGGCGGTCTTTACCAGTAAAGCTACTATCAAAGTTTAACCGGACGCGATCGGCAAAAATCACATTTTCATTGAGTTCTGGTCTGGTATCACCACGATTTTGAGCATCGGTGTTGATTGCTCTATCGGAGCCAAATGCACCAGCCAGTGCAAAAATTGCTTCTCCTCGTAGTTGAGTAGTTGTGGAGAATTGTTGCGACTCTAAGGTGGCGGTACGAGCTTCTAGAGCATCTACTTGACCTCGCACAGTTTGCAACTCAGCAGTATACTCTTCTTGCAGCTTTTGCAGCGTTGCTAGGTCTTCTTTTTTCACCAGATCAACCGTACTAGTAGCTATCAGTTGATTTATTTGATCTAAACAAGCATTCAAACCAGCAGCAAACTCATAGCGAGTCAAGGCACGATTACCCCGATAAGTTTGGTTAGGATAACCTGCAATGCAGCCGTATCGCTCAACCAGGGATTGCAAAGCCTGGAAAGCCCAGTCTGTAGGTTTGACATCAGAAAGCTGTGAAACTGAAGTTACTTGTCTGATATTCTCAGCACTGCTAAAACTGGACGGTTGATTTCTTGCAGGTGCTTGATTTAAAGGTACTTCAGAACTCATCGCTGGTACTGCAACTATAAATAAGCCTAAAATCGCTGGACTATATAACAAAGAATTCAACCAAAACTTTTGCACGAATGTACCTCACACGTAATAGAAATTAGTGAAAGATCAAAAAAATTTAACATTGAAATTTCTGCTAATTGGTAAATCACAAATACTAGCAAGATTTAAATATTTTGTGAATTTAGCCTTTGTTTCAGAAATATTAATGTTACACAGGAAAAAGTTAATTTTTTTATAATATAAATTTTCCAAATCAACTTTAAGAATATCAAAGCACAACTAAGTACCACAATTTAGAGATTGTTTTGAAATAAAGACAATTGTCATTTGTTTACCTATTCTTAACTAAATAGATATTGGTATGTTAAAGATTATCTGTACTTTTTAAGTCAACAATAACAAATATTTAAGATCAAGCTAATAACATATTGTTAAAGTTTTGTAGAGTAAAAATCTTATTTCCTTGGGCTTATGAATTAACAGCAAATATCAAATATAGATGATTTGAAAAACCACATCTGTGATAGAGGCAATCCATGAATTGCCTCTATAAAAAGCCAAAGAGGTATACAGTATAAGCATTTTATTGATTTGAAATGGGTGGTTTATTTACGCCGTCCTCTACTAAACTCCTAGCGAGTTAATTATATTTTTCCAAAAAATTAGTTTTTTCTTAATTAAATTTTAATTAAAATATGTAAGATAGTCTATCTATTATAAGCTTTATATTATATTGGTATACATCCACAATTGGCTCACTCATTAGATTGATAATTAAAAAATTAAATCATAAGTTATCCTTTTCTTAATTATTTCTTAATTAAAAAACCTTATTAATATTAATTAGAGATATCTAAATGTCAAAAAATGGCAAGTACAGTGGCTATCGAAGTTAGTAATCTCTCGAAGACTTTCAAAGGTAAGACAGCGCTTAAAAACGTATCTTGCACAATTAATGAGGGAGAACTGGTTGCGCTTATAGGTGCATCTGGCTCAGGCAAATCTACTCTGTTACGGCATATTAATGGCTTGCACATTGGAGACGGAGGAACAGTTTATATTTTTGCTTCAGTCCTACAGAGTAGTGGGAAAGTTCACTCTAAAATTAGGTCTTTACGAAGCCAGATAGGTTGTATATTTCAACAGTTTAATTTAGTCAATCGGCTAACAGTTATCGAAAATGTTCTTGTTGGTAACTTAGCAAGATTGTCTATTTTTCGCTCAATATTACATTTATTTACCAAAGAAGAAAAAGTTCAAGCTCTTGCTGCATTAGAGCGGGTAGGCATTCTTGAACACGCTTATAAACGGGCATCTATGCTTTCTGGAGGGCAACAACAACGAGTTGCGATCGCTCGTTGTTTAGTGCAAGGAGCGAAAATTATCCTCGCAGACGAACCAATCGCCTCTCTAGATCCTGAATCGGCGCGTAAAGTTATGGAATTGCTCGTGCAGCTAAATCGCCAAAGCGGAATTACTGTAGTCGCTTCGTTACATCAGGTTCAAATGGTGCGTAGTTACTTTGATCGAGCGATCGCTCTCAAAGATGGAGAAGTGATGTTTGATGGTGCAACCACAGAGATGAATGATCACAAGCTCAATGAACTTTATGGCACAGCTGCCGAAGAACTCATTATGAGAGGGCACGGTGAACTGGTAGTGTAACCCCAAAATACAGAATTTTTACTTAATATCTCACAACTAAACTTATGGACAGAAGGTTATTTATTCAGCAGGCTTCTTTGTTTACTCTAACTTTGGCAAGTGCCAAGATACTTTCAGCTTGTACTTCTAATGCTGATAATAGTACCGCAGCGATTAAAGAAATTAACTTTGGTGTTCTGTCTACAGAATCTCAAGCTAATCAAAAACCAATTTGGGAACCTTTTGCTGCTGCTATGTCTCAGGAAATTGGGATTACCATTAAACCCTTCTATGTTACACAGTATGCAGCAGTCATAGAAGCTATGCGATTTGGTAAAGTTCAAGCAGCTTGGTTAGGTGGTAAATCTTATATTGAAGCAGCAAAAATTGCTGATGCAGAAGCTTTTGCTCAAGTTGTGAGTGCAGATGGCACTAGAGGCTACTATTCTCATTTAATTACTAATAAAGATAATCCCATCACTGCGGAAGCTATAGCAGTAGGTGGCGATAAATATGTGATCAAAAATGCAGCCAAGCTCACCTTTGCCTTTAATGAGCCTAATTCTACCTCTGGGTTTTTAGTTCCCAGTTACTATATTTTTACTAAAAATAATGTTGACCCTAAGAAAGCTTTTAAACGCTTGATTTTTGCTGGTAATCATGAAGCTTGCGCTCTAGCTGTAGCTAATAAACAGGTAGATGTAGCTACCGTCAGTAGTGAAGCATTAAGTCGTCTAGAAAGTACTAATCCTACAGCCAGGCAGAAGATTGAAATTATTTGGAAATCACCTATAATTCCCAGCGATCCAATTGTTTACCGTCGGGATTTATCTGATGATATCAAAAAGAAATTGCAAAACTTTTTCTATAACTACAAAGATGCTAAAGTTTTAGGACAATTTAAAATTTCTGGTTTTGTACAGGCTGAAGATAAAAATTGGCATACAATTCGAGAACTAGAAATTGCTAAAAAAATCCAAGAGACTCAAGCCAAAGAAAATCTTAGTGAGCAAGAAAAACAGCAAACAATAGCAGAATTAAACCAGCAACTCAAAGGGATTAAATAAAATTAGATTTATAGGTAGTAAAAAGTGCGCTCACGAAATCAGATAATTACTTACGTATCTCCTAACGTCGCAGCAATGTTAGAGAAAGAAGCAAAGCTTGTGAATACTCAAAAAGTTTTGTTTCTTTTAGTTATTGCTGCTGTATTGGTTTTTGCCTATAACCAAAGCGAGTTAAATTTCCCTGTACTTCTGCAACGGGGAGACAACATGGTGGAATATATCCGTTCATATTTTCCGCCAGACTTTAGCGATTGGAATTATTATTTCTCAGAAACACTGGTTACTATATCGATGGGAATTTGGGGAACTTTAATGGCTGCGATCGCAGCTGTTCCTTTATCTATCCTAGCATCTAATAATATTTGCCCAGTATGGGTTGTACAACCAACACGTCGCCTCTTAGATGCTATGCGTGCGATTAATGAAATCGTCTTTGCACTAATCTTTGTAGTTGCTGTTGGATTGGGGCCATTTGCTGGAGTTTTGGCATTATTTGTTCATACTGCCGGTATCCTGGGTAAGCTGTTCTCAGAAGCAGTAGAATCAATTGAGTCAGGCCCTGTAGAAGGAATTAGAGCTACTGGTGCAAGTCCGATTCAAGAAGTTATTTATGGAGTGATTCCTCAAGTAATGCCTTTGTGGACTTCTTTCACTCTCTACAGATTTGAGTCAAATGTGCGTTCTGCTTCTGTATTAGGGATTGTTGGGGCTGGTGGTATTGGCGTTTCACTATATCAGAGTTTTGGTGCATTTGAATACCAAAAAGTCTGTACAATTCTCATTATTTTGATTGTTACTACTGGTGTTATTGATTTACTCTCTGCAAAGGTTAGAGGGTGGTTAGTTTAGTATGACTGTCATCAGTCATCATTCAACCGCTAAGTACAGCTTTGCTTAAATTCGTAGCGAATTGACAGGGGTAAATTGTTGACGGTAAGGTGAGGATACGTGGACTATCCCTCAAGCATTCGGTACTATGGCTGGTCGGCAAAAAACCTACAAGGTGCAGCTAACAGAAGAGGAAAAAGAACTGTTGCAGCAGCAAGCGAATGCCCGAAAAACAGGGCAAAGCAAAGGCAAACGAGCCAAAATAATACTTACAACTGCTGAAAATTCAGATTGGACAGATGCTCAAATTGCTCAAAATATCGGCTGTTCACAAGCCCTTGTTCGGAAATGGCGCAAACGTTGGTGTCAAACTCGTAGTCTAGAAGAAGCACCCCGTCCAGGTCGTCCTCGGATATTTGAAGCAATTATACGAGCAAAAGTTACTGCGTTCGCGCTTCGCGTTGCCGCAGGCATCGCTTGCAGCAACCCAACGGATTTTGATCTTCCCTTGGCGAGGTGGAGTTGTAGCGATATTGCAGCACATCTAGTCACGCTAGGCATTGTAGTATCCATAGCGACTTCAACAGTCTGGCGATGGCTAAAATCTGAGCGGATAAAACCTTGGCGGTTTCATACTTGGATGCATCGGATTGATGATAATTTTGTTGCAAAAGCAACCCCTGTACTTAAACTGTATGCTCAGGCAAAATTTTTGATTAAAGCTGGATTCTGGGTGGTATGTGTGGATGAAAAAACTTCCATCCAAGCACGATCCGGCTTACATCCAAATATTGGGGCAGGTGTCAAACAACCAGTTCACTTTGCAGCCAGATATGCCCGAAAAGGAGCAACACATCTTTTTGCGGCTTTGAGCGTTGCTGATGGTCTGATTTATGGTTGTTGTCGCCCAACAAAAACATTCCTTGATTTTCAAGGATTTCTTTTAGAAGTATTGATACCAGAAGCCATTCGTCGGGGTATGCGCCATATTTATTTAATCCTTGACAACGGCTCTACCCATGCCCCAAAACAATTACAGGCTTGGTTGAATCAGAAGCAAAAAGAAGACGGTTGGAATTTTACGGTGGAAGTGGTCTGGCTACCAAAATATGCTTCATGGTTAGATCAAATTGAAATTTGGTTCAGCATTTTACAACGTAAATTACTGACTCCAAATGATTTTCCTGACCTCAAGACCTTACAGCAACGTATAACTGATTTCATCGTCCGTCACAATGATTCAGCCCAACCAATCAAATGGTCATATACAGTAGCCCAGATGATGGAGAAATTCGCTACGAATTAA

Protein sequences of DBSCAN-SWA_3

>NZ_CP046705|186481:233000|203056_204169_+|WP_114081270.1|DBSCAN-SWA
MSFKKLFLVACGLLVAIVISILTGTKVIAQSTTDLALALYHAPIHYQDTDSTKYSGDYITRFDYDNNWRGTNNWDNLILFPLSAHAYYSVAETCTHWFITYSFYHPQDWTDIPFDQEHENDLEGLLTIVRKDGSAFGKLEGVVTVFHNDFYSYTPTGSPLRNGAESIDGTLTMNSYSGSLHPLTTQEAKGHGLKAWPYAGNFKGASSEDGIIYYPNGTTAELPASGNDRDVQYQLLDVFANNGMWQHQLNEASLSSSSALTFASWGTFKGDSSGGCGAGTPTCSTNSANTPWGWDDSNDGAVYKGEMALDPAHLTDVYFDGLGTFDTAYIRNQFIQGLKDRGYNSANLPQGWPTQLNLNSLIGKLKNQCS
>NZ_CP046705|186481:233000|219582_220071_-|WP_114081253.1|DBSCAN-SWA
MRRIIIGVMGRGENATANDLQDAYILGQFIAKQGWVLLTGGRNVGVMDAVSKGAKSADGLTIGILPGGNQDGMSSWVDIAIFTDMGNSRNNINVLTSDVIIACGMGAGTASEIALALKANKQVILLNNDQESKLFFKKLSPENVYIVESVEQAIATAKIILS
>NZ_CP046705|186481:233000|214028_214445_-|WP_114080950.1|DBSCAN-SWA
MKGWVNDPHSGGVKIPEQVKQRTKHRILAYAEQHYAGKYIRIDVRFKGYFCYIDAYKEPFLPDNDDLSMFKITRSEYIERAKNTPIHLCRLRYKGNEEKWTKAFYTYSNEKYEPSVFNNGTFYGTPEEAFQSSALYLD
>NZ_CP046705|186481:233000|230941_231715_+|WP_114080750.1|DBSCAN-SWA
MLEKEAKLVNTQKVLFLLVIAAVLVFAYNQSELNFPVLLQRGDNMVEYIRSYFPPDFSDWNYYFSETLVTISMGIWGTLMAAIAAVPLSILASNNICPVWVVQPTRRLLDAMRAINEIVFALIFVVAVGLGPFAGVLALFVHTAGILGKLFSEAVESIESGPVEGIRATGASPIQEVIYGVIPQVMPLWTSFTLYRFESNVRSASVLGIVGAGGIGVSLYQSFGAFEYQKVCTILIILIVTTGVIDLLSAKVRGWLV
>NZ_CP046705|186481:233000|220646_220838_-|WP_114081252.1|DBSCAN-SWA
MTKEYMESLEAIVDQLTLAAVLEMLERISHKKAENLRNHWKDEASAKLWDKAARQIEQMNIDV
>NZ_CP046705|186481:233000|217710_218550_+|WP_114081250.1|integrase|DBSCAN-SWA
MRIIRQLLLWIVEHPGSGGDFQPEQLTKTAMEIYLAYLDTSGYSIAHQARVKSAVSGFARWLIEEKGILRRNPTRGLNIPAQPLLAPRQLTPDQRYILRNLIEKDGHPRSMAVFALGYWAGCRVSDVSWLRIEHTHIGPKVGWLHVGYKGGKARDIDLINAVRKPMYEYIHHGGRDTESDYTFTSQRNERLTEAGIHRWWKNIKAQATVSEWELIHDVTFHDLRHDFAHRAREAGWTLEEVAYYLGHITKKGTPAIQTTVRYTQSSRQQVKDKLALLKG
>NZ_CP046705|186481:233000|218771_218924_+|WP_159402652.1|DBSCAN-SWA
MRAATTIVVSQLSDAAEPQLVENAEDVAQPMENFLGSDDILNSLKTKRIG
>NZ_CP046705|186481:233000|231959_233000_+|WP_167756004.1|transposase|DBSCAN-SWA
MLTTAENSDWTDAQIAQNIGCSQALVRKWRKRWCQTRSLEEAPRPGRPRIFEAIIRAKVTAFALRVAAGIACSNPTDFDLPLARWSCSDIAAHLVTLGIVVSIATSTVWRWLKSERIKPWRFHTWMHRIDDNFVAKATPVLKLYAQAKFLIKAGFWVVCVDEKTSIQARSGLHPNIGAGVKQPVHFAARYARKGATHLFAALSVADGLIYGCCRPTKTFLDFQGFLLEVLIPEAIRRGMRHIYLILDNGSTHAPKQLQAWLNQKQKEDGWNFTVEVVWLPKYASWLDQIEIWFSILQRKLLTPNDFPDLKTLQQRITDFIVRHNDSAQPIKWSYTVAQMMEKFATN
>NZ_CP046705|186481:233000|193456_193924_+|WP_147262447.1|DBSCAN-SWA
MMESPRSYYDAEFGQIILEDNYWTLAQCAVLGDRRVPICLDFEQGQIGELSSLQREAIRQALALPPDVLHVTAPLVLQNYDVYREMIVDESMPLLANPIQVWEQVTFSYIYVEYDLDIATFKLIAECDWEPEHGLEVRFRNGVADDVDQIGETGR
>NZ_CP046705|186481:233000|223196_223445_-|WP_114080757.1|DBSCAN-SWA
MQEFKSPVSRLVRLFQKGRDSWREKALEKQKKVRALEIKVRDLTASREYWKQRALAAESEIKEQRIGGVSEKKKKMLARTST
>NZ_CP046705|186481:233000|205779_206802_-|WP_114081515.1|transposase|DBSCAN-SWA
MIINSFPKIVKDILRGLPKNDYPVLNSRLFFECWLSYAMDNSLTSMRDLFKRLNNTGFEVDISTFSKANLHRSQKPFQEIYQKLNELVQKKVQKKLHDKYAICPIDSTIITLTSKLLWVLGHHQVKLFSSLNLATGSPSNNFINFGHDHDYKFGSKMMSSLPINAVGVMDRGFAGLKFIQELVQENKYFVLRIKNNWKLEFDGSNGLVKVGASGDAQAYRVINFCDLEAKTEFRLVTNLPSHGEAAVSDDEIRDIYRLRWGVELLWKFLKMHLKLDKLITKNVNGITIQIYVSLIAYLLLQILSIPQQWGHTLLDKFRYLQSCMCQKISYVHWFEEMMSC
>NZ_CP046705|186481:233000|189219_189729_+|WP_114081267.1|DBSCAN-SWA
MKLLNFLKSRPVIIVLAIAVNITGIDVHSSTSNFPIRKSTITQSQPQIQLVHTLTGHKKVTFGVRAVAISPSGQTLVSGGRDDTIKFWNLRTGKLLHSLDAQSDGITSIAISPDGKRIVTGGISTPTMKVWDLRTFLMLKGDSGHTQPVETIAISSDGKGLPENKIYSQ
>NZ_CP046705|186481:233000|226583_228224_-|WP_114080753.1|DBSCAN-SWA
MQKFWLNSLLYSPAILGLFIVAVPAMSSEVPLNQAPARNQPSSFSSAENIRQVTSVSQLSDVKPTDWAFQALQSLVERYGCIAGYPNQTYRGNRALTRYEFAAGLNACLDQINQLIATSTVDLVKKEDLATLQKLQEEYTAELQTVRGQVDALEARTATLESQQFSTTTQLRGEAIFALAGAFGSDRAINTDAQNRGDTRPELNENVIFADRVRLNFDSSFTGKDRLRVRLQARNITSFNTAVTGTNQTRLGFDGNESNNVSVSALFYRFPVGNSTTFNIATEGLEYIDEVPVLSRNFDSSGSGALSRFGRYNPIYRAAEGPGIIINQKFNDALTLTAGYVVPSGVGNDPANGRGIFNGSYSALGQLTFQPTSELSLAFTYVNAYYTDGSGVTGSTGTGFANNPFNGARTSVNNYSVTGNYKLSPKFTITAWGSYANAQAENTAVARSNAEIWNWAIQLGFPDLGREGNFGGIVFGVPPYVADNQFVNGNNRRQDDNISYHLEAFYRYKLNDNIAITPGLITILNPEGNSNNSNIYVGVVRTTFTF
>NZ_CP046705|186481:233000|201576_202599_+|WP_114081515.1|transposase|DBSCAN-SWA
MIINSFPKIVKDILRGLPKNDYPVLNSRLFFECWLSYAMDNSLTSMRDLFKRLNNTGFEVDISTFSKANLHRSQKPFQEIYQKLNELVQKKVQKKLHDKYAICPIDSTIITLTSKLLWVLGHHQVKLFSSLNLATGSPSNNFINFGHDHDYKFGSKMMSSLPINAVGVMDRGFAGLKFIQELVQENKYFVLRIKNNWKLEFDGSNGLVKVGASGDAQAYRVINFCDLEAKTEFRLVTNLPSHGEAAVSDDEIRDIYRLRWGVELLWKFLKMHLKLDKLITKNVNGITIQIYVSLIAYLLLQILSIPQQWGHTLLDKFRYLQSCMCQKISYVHWFEEMMSC
>NZ_CP046705|186481:233000|194810_195503_-|WP_114080594.1|DBSCAN-SWA
MLEQQPENLQFYIKQLATEALQKSDPSAWFEVLYAKAKGDTAQIPWAKLAPHPYLQDWLTNHEPFAFGQKALVIGCGLGDDAEALVNLGFEVTAFDISPTAIAWCQERFPNSTVNYIVADLLAIPSQWHQAFNFVFECRNIQALPLNVRSWVISSVTSVLAPGGTLLMITRIRDTESEPSGPPWPLSNSELAQFKDLGLYQVEQLVFLEPGQIDVKQVRIEYRRHNSLSK
>NZ_CP046705|186481:233000|218966_219419_-|WP_114081254.1|DBSCAN-SWA
MINQITALESCWHISPEWGQTMPPVAVRMLEKVLLPISDLSGYCCGVLWEKQEWIYAIVCQNETLYLAEQEFYTTNVLKKSTVSTPAFRLGDIVEVDFGERPTRRIIQGIFSLKDNWLYGVEWRSPTLEEMSAQSRTIWLADVDLVNVSV
>NZ_CP046705|186481:233000|198491_199865_-|WP_114080598.1|DBSCAN-SWA
MLKHIQQIAAVFILTLGFASTSVAATPRSTWVENEIYQYNHPFASQLPQELATKMQKMTASPFAFYRGTAHIFYRDMQTLPGSGFVNSSTSAIWLEGDMHLQNLGGMRNSNDNNVFDTTDFDEGYLGPYVWDLRRMAVSILLAAKENGLSSSDAQDIVRNFLDAYLNKMSDFKGTNDELSYRLEESNTNGVVKDLIQQSAAKSRSSLLNKYTLLNSSSNRVFQTTSELQPVSSSTYLDITGAMSSYINSVPSSKRYSNSYYTLKDIRLKLGSGTGSLGKYRYYLLIEGPTSATDDDRILEMKQQASSAVAIAVPGLLPSSVYGNHQGTRVTIATKAMLSNTDPLVGYTTVSGIPFMLHEKSPYQVDFDYTLLTTKSKFMDAMGYAGKVVAKNHAISDQDYDASIVSESVDKQVTDITSGNKAVFKDEIVNFALDYATQVQYDYTSFVNAYNSGVTLY
>NZ_CP046705|186481:233000|225002_225509_-|WP_114080754.1|DBSCAN-SWA
MAKVTISIGLTDAEVKALSAMQISENESLNHTATRLLQGILGQTKAGLALSNGDEIKEIVKQEVNALAASTPDGEEIKQVIRQELAQAIAQIKGLIEKGSGEVALQTQEAVSVEQQVLPDYSAIRENILSKLKTGKQSAAKAIDAFIESLGAVKEEQQPATVELDVAS
>NZ_CP046705|186481:233000|195596_195761_+|WP_159402650.1|DBSCAN-SWA
MNDLFDCASSKQASVYSPSQDEPNTNYHSPLGAFVNLASTVQYKTALDESWSSF
>NZ_CP046705|186481:233000|212684_213635_-|WP_114080949.1|DBSCAN-SWA
MPSPTTDLVHSYLKEIGRYPLLTPEQEITNARLVQQMMAIEEQRASLAVQLNREPTTRELATSLGQTEAEVQSIIQQGQKAKEKMVTANLRLVVSVAKKYQNHNLDFLDLLQEGALGLQKGIEKFDPNRGYKLSTYVYWWIKQSITRAIGEKSRTIRLPIHINEKLNKIRRVQQQLSQSLGRPPVVAEIAESLNLLPNQIREYLHVSRAPVSLEMRVGDERETELADILPMDGISLDEQIAQELLHQDLSKLLALLNPRQREVLTLRFGLEDNQQLTLSQVAKRLNLSRETIRKSEHLALKILRSHQNKIKDYLLN
>NZ_CP046705|186481:233000|229864_230866_+|WP_114080751.1|DBSCAN-SWA
MDRRLFIQQASLFTLTLASAKILSACTSNADNSTAAIKEINFGVLSTESQANQKPIWEPFAAAMSQEIGITIKPFYVTQYAAVIEAMRFGKVQAAWLGGKSYIEAAKIADAEAFAQVVSADGTRGYYSHLITNKDNPITAEAIAVGGDKYVIKNAAKLTFAFNEPNSTSGFLVPSYYIFTKNNVDPKKAFKRLIFAGNHEACALAVANKQVDVATVSSEALSRLESTNPTARQKIEIIWKSPIIPSDPIVYRRDLSDDIKKKLQNFFYNYKDAKVLGQFKISGFVQAEDKNWHTIRELEIAKKIQETQAKENLSEQEKQQTIAELNQQLKGIK
>NZ_CP046705|186481:233000|220195_220471_-|WP_084227073.1|DBSCAN-SWA
MSCEHLDNLTTETLISKANYPVFRCEECILINSRWVHLRICQSCGKMLCCDSSVHQHARRHYEETGHSVISSAELGEQWLWCFLDEQAKNY
>NZ_CP046705|186481:233000|208974_210297_-|WP_114080946.1|DBSCAN-SWA
MSIFAQHSVFIRHFLKLASVNVLSNLMVPLAGLIDVMFLGHLTEIRHLAGVAIATILFNYIYWTFGFLRMGTTGMVAQAIGRKDNQSAVLIGLQHGILALILGLAILIFQQPLQILGFAILSATPEVKSSGVDFYNALVWGAPATLINFVLIGWFLGQAQSSRALLLSAISNCANVLLDYLFIVQWGWSSRGAGLATATSQYLMLMVGILLYCQTISFKQIQALIGELFDLSALKSAFMLNGEIIIRTFALISTMAMFSNLSSMLGTEILAANTLLMQVVSLAAYFIDGLAFATESLAGIFQGSGNITSLKQLLQTSVVSSLVIGLMFATAFIFAPESLLRLLTNHTEIINNLRSYIPWLLPVLGFGSVAYALDGYFLGLTQGHTLRQAMLKATVIGFIPSAITAMYFHSSHLLWLSMSLFMATRTITLALCVPKSFSKR
>NZ_CP046705|186481:233000|212006_212267_-|WP_159402651.1|DBSCAN-SWA
MPSATSTQEISSPYRQEETQSYDLQEWEGYSWVIFRFEVRAIPSLLLSETLREREATPFLRNALAFGTPLTNTKLVGFAAKVITIP
>NZ_CP046705|186481:233000|187041_187542_-|WP_114081708.1|DBSCAN-SWA
MSRPFEIEIAESEEELKKRLQTANLGNQKEKLIMLWWIKSGQAKEQQDIGKRLAKDTSTVTRWLQKYRSGGLDELLKIKKAPGAKRKIPEGAITALEEELKTGKGFSSYGAIVEWLKQEQGLDIEYATVYALVRYRLGAKLKVPRPQSHKQDEKLVSEFKKNSVSF
>NZ_CP046705|186481:233000|195996_196464_+|WP_114080596.1|DBSCAN-SWA
MSRLHIREDDLTGKNIANLLREHLENMHEITPPESVHALDIEALPSPDITFFSATDGEELVGCGALKELSSTSGEIKSMRTALAYRRQGVASKILEHIIKEAQRRGYDCLNLETGAISEFASARALYTRYGFEYRSPFGEYIDDPNSVFMTKKLA
>NZ_CP046705|186481:233000|189885_191108_-|WP_159402613.1|transposase|DBSCAN-SWA
MQLTDSLKKLLKETAHQLKGAAKRRFIAQTVVALGHGGKSIAERELGWNRVTIGKGIKELNSGITCVDNYQGRGRKKAEEHLPTLLEDIKKLVDSQSQIDPTFKSQRLYTRLGASVVRHQLIEKFGYAEEELPTSETIRVKLNDLGYRLKRVAKIQPQKKFPETDAIFEQLAIVHQEASDDPTILRLSLDAKARVNIGSFDRGGRNRVPTETDDHDFKPKTTVAPYGIFLPDLDELFLYFTESKVTSDFIVDILGDFWKSESWRFSEIKTLLINQDNGGENSSRRTQFMKRIVEFAQSYKLNIRLAYYPPYHSKYNPIERTWAVLENHWNGSILDDVETALNFAKTMTWNGKSPVVKLVTQTYSSGVRLTKKAMQEIENKIERLTNFTEDNLPNLGKWFIDICCGVT
>NZ_CP046705|186481:233000|220936_221077_+|WP_159402653.1|DBSCAN-SWA
MPTKVTVKVLLKAYVCLSLLPAELKAMPAASYAGADNPTNPIIMKF
>NZ_CP046705|186481:233000|214816_215788_-|WP_114081249.1|DBSCAN-SWA
MLTEVMEHFRLVKEFPKAGYYETDHQKQMFKDIKAAIHSGKLIAITGIIGCGKTTTLRRLFDVLEKEGKILVSKSLSVDKERATLPTLIAALFYDLSTDKEIKIPKDGEKRERELRDLIRKGKKSVALFVDEAHDLHYSTLTGLKRLIEVVEDGGGTLSVVLAGHPKLKNDLRRPTMEEIGYRATVFSLEGIVGNQREYIEWLVSECTISDTPIGEILEAEAIELLATRLLTPLQIEQHLTLALEAAYRVAVKPVTTVIVESVLSKQIDDLEPTLTRHGYDVRGLAEQFNAKPAEIKSLFRGQLDPTRARELQEQMLAAGLPL
>NZ_CP046705|186481:233000|221088_221574_+|WP_114081255.1|DBSCAN-SWA
MLKRIDHIYLSVSNFSQSETFYDLVMRELGQHKGDKVIAEEPHAHYFGPQFQLTIQPARSAQKHDPYAPGLHHLCFQVETMTDVDLCFKKLRSVGINVSQPKRYPEYHPEYYAIFFDDPDGIRLEIVAKTSTRQALELRWDELKEFLNPLQTLPNTEFHNA
>NZ_CP046705|186481:233000|206972_207701_+|WP_114080944.1|DBSCAN-SWA
MLQVVRQIKQRSKVQLKRKDITYELWRLDDGEFRKLRQKSLPIKDDYMFYMHFYLSERENKNKLNLAELYVCLTHLFGDSSDWIDDWKGTFSFPVLLVLEKAQGRFFYLINIYDDRGTLYISFYRVLEAEVEGYDTQIFREPFEIEFSRQEINYFISYFYGYLQGCFQSRRLLIPSEQFFKKIRSEYIVYGYKDEHYFEEKYQSQSEYLAAIESLESIGISSITSQNVNNILQSITSEIIGN
>NZ_CP046705|186481:233000|224793_224982_+|WP_114080755.1|DBSCAN-SWA
MPSISYNRTDSQQPQSITVEGYVVRPGLHILTYEQLKLLREQTQHHSQLEHLVSQGVIKLTG
>NZ_CP046705|186481:233000|188049_188211_+|WP_114081269.1|DBSCAN-SWA
MNKKWATKRLTINLASGEAERLEKYCSITGRPATDVIRELIRSLPTEETPNAN
>NZ_CP046705|186481:233000|196935_197679_+|WP_114080597.1|DBSCAN-SWA
MEFNPNNNVVKLCLQGMGMEERGKPEEASKLFLQAWNEATYDFEKFISVHYVARYQKNISDKLKWLETALQFALKINNNTVKSAFPYLYSNIAKCYEDLSDPDKARKNYELATSFKDKPSDKGPFYHGTKADLQVGDLLTAGGSSNYKLELKMNHIYFTALVNGAGLAAALAKGDNRERVYIVEPTGEFENDPNVTDKKFPGNPTRSYRSQAPLKIVGEVTDWVRQTPEELQKWREKLANNKGEIIN
>NZ_CP046705|186481:233000|207828_208431_-|WP_114080945.1|transposase|DBSCAN-SWA
MHASEKYTERVQKLRAEYWTTIGSVLLEDLIFIDEAGVNISMTRRFARSLQGSRAYGDCPNARGKNVTMIGAMSTQGIIAAMTFTGGTNASAFQTYVTQVLVPNLWPGATVVMDNFSSHKVAGIREAIEGVGAKLVYLSPYSPDFSPIENCWSKVKEFLRSLAARTYQELDQAITDAFNAVTKKDIIGWFTHCCYYIAPN
>NZ_CP046705|186481:233000|229022_229820_+|WP_114080752.1|DBSCAN-SWA
MASTVAIEVSNLSKTFKGKTALKNVSCTINEGELVALIGASGSGKSTLLRHINGLHIGDGGTVYIFASVLQSSGKVHSKIRSLRSQIGCIFQQFNLVNRLTVIENVLVGNLARLSIFRSILHLFTKEEKVQALAALERVGILEHAYKRASMLSGGQQQRVAIARCLVQGAKIILADEPIASLDPESARKVMELLVQLNRQSGITVVASLHQVQMVRSYFDRAIALKDGEVMFDGATTEMNDHKLNELYGTAAEELIMRGHGELVV
>NZ_CP046705|186481:233000|221880_223113_-|WP_167756041.1|DBSCAN-SWA
MDCGISFRAAEKVFELFNSESKITPSFTCIRKWLGRMGIYELTRKKEYRDDWIFIVDFTLELGKQKALVVLGVSQEHLSEQVVSKRRALSHEDVELLGLEIMGSTKGEMILHQLEKITELVGVPVQIVADHSSDLARGIKLYQENHPEIIYTHDVTHAMALLLKYKLDANDRYQSFLQKCHRCRQKLQQTELSFLSPPSQRSQCRYFNVERLTNWAIKLLNSPVETLIQLMPDIEHKLILSKIVEKLAWLADYETDLIHWNQMVTMTRRLETQLKQLGLNSQTLQYFQQNQSDLVNDSLQYFQQQIFDYVTNECSQIKDKQTFLATSDIIESLFGKYKQFSARCPIKEMGQMLLTICLSTMNLTTTVVKNALESISFFDVEEWLAEVFGQSMLSKRKTLYSTQINDTETA
>NZ_CP046705|186481:233000|224034_224541_-|WP_114080756.1|DBSCAN-SWA
MWESNVIAIPKQLINSQIKSPQVFLIDHENNNRGLTDINEALQLAESLELDLVLVSEGKEAPVAKILNYGKLQYQKKKRQAQSARPVVKEVRFGLNIGVADYKLRIEQAVGWLSKGDSVKFAVRLRGREHQYRDQAGELLDRVVTDLNSVGKVQSLDKRSLIALIIPA
>NZ_CP046705|186481:233000|194294_194591_+|WP_114080593.1|DBSCAN-SWA
MNKGELVDAVAAKANVTKKQADEVISAFLSVVTEAVANGEKVTLIGFGSFERRVHEVCRRYRSEREGRNPKTNEPMTIPATKVPAFSAGKQFKEKVAP
>NZ_CP046705|186481:233000|192119_193349_+|WP_114080591.1|transposase|DBSCAN-SWA
MLHKVVQVRLYPSVEQQNQLAQTFGCARWWWNYALNKSVETYKETGKGLSRVALNSFLPALKKAENTAWLADCYSQVLQATTLNLTTAYKNFFEKRAGFPKFKSKHGKQSIQYPQNVKIVDGNVKLPGNIGVIKAKIHRLIEGKIKTVTVSKTPSGKYLASILTELEGENQVTSEGKIYGIDLGLKHFAVVTDGEKVSFYDNPKHLAKHEKNLKRKQKKLAHKQKGSKSRNRYRKVVAKVYERVSNSRQDFLHKLSYKLVSDSQAVIVENLNVKSMVRNHKLAKSISDVGWGTFTNFLAYKLERRGGKLVEIDRWFPSSKLCSNCFYQIGEIPLDIREWTCPHCHTHHSRDANAAQNIRAEGIRMIKAEGSAVSAVGGEVSPTLGRKSKFRHSLTITEAPTSTVLGKLA
>NZ_CP046705|186481:233000|215777_217424_-|WP_114081251.1|integrase,transposase|DBSCAN-SWA
MPAEALTNLRHRLDMLPSRCQERRQLMEETASLYGVSIDTLYRALRNSSRPKSINRSDSGTPRKLSQAEMELYCEVIAATKIRTCNKKGRHVSTARAIELLEDFGMNTPQGFIKPPKGLLTKATVNRYLKTWGYDHLTMTRQPPAVRFQATHSNECWHFDLSPSDLKHVKQPLWVETGKGNPLLMLYSVVDDRSGVCYQEYHCVYGEDVTAALRFLFNAMTASTSDGCPFQGIPEMIYTDNGPIAKSHVFQNVMDCLGIKLASHLPAGKDGRRVTARSKGKVERPFRTVKEAHETLYHFHEPENEVEANLWLRQYLLNYNDQKHRTEAHSRLEDWLRNLPKSGIRQMCSWERFCTFAREPQRRKVDATARVSVEGVAYEVNPDLAGETVVLWWGLFDNELYVEKGDQRYGPFYPVDGPIPLHRYRKHKKTKTEERADRIADLALKLGLPRTALDKNADLQFLVDKYKEIEPTVTPFKDPDPFQEFTYPTVLFAKLAISDYLAKPLAKLSTEQIAFIDGLLAETLNKKVIIERVRQYFHSNKGGQQNAH
>NZ_CP046705|186481:233000|191205_191847_+|WP_147262446.1|DBSCAN-SWA
MIIIFIICIFYFLEVPKLIASGSDDRTIKLWDLHTLKLLDTIPAHSGFVSKVAFSPDMQTLVSSGGGDDNTIRLIDLQTKKTRHILKGHKTGVDAIAITPDSKKLVSGSFGQLVSRNRAISTLKLWNLQTGKLLHDFTDNFNSVESLVISPNGKILICGNYDGSIKLWSLETLKPLHTFQDGSSSVLGLALSRDGKTLVSSNEDSTVHIWQIK
>NZ_CP046705|186481:233000|211251_211971_-|WP_114080951.1|DBSCAN-SWA
MAGFNDLSSQQFYHGTKADLKLGDLIESCNPPDVGERDRMATYVYLTPNLDAAIWGAELALGEGHGKVYIVEPLGQIENVPELTKQKSPKHLSMSYRSREPLWVTGTVTELTLYHGTRADLKPGDLIEPGYHSNYGQRKKATYVYLAATFDAATWGAELALGEGRGRIYIVEPIGPIEDDPNVTDKKFPGNPTKSYRSREPLRVMGEVMDWQGHSPEAIKTMKDNLERLKQLGIEAIED
>NZ_CP046705|186481:233000|186481_187051_-|WP_114081709.1|transposase|DBSCAN-SWA
MILNCLEKHLAPGKCVRYLCQDETRVGLKTLTGKVITASGVKPTVEVKWPRENFWIYGAIEPLTGDHFLYEYPKLNGECFQQFLDWLSQQLGGDYAILQVDQAPAHTSSAIRWPENIIPLFQPPSAPELNPIERLWQLLKKPLKNQLFSSLQNLRDRIQEIFNQLTLEQVISISSYNFILEALFYAASY
>NZ_CP046705|186481:233000|210599_211124_+|WP_114080947.1|DBSCAN-SWA
MSMISFRPMILIIGISIGLLPLLSNWQVLAQNQSQNIELKVYSENEQKQSCPDKVIVTEKPHPYQEGSFSTDGSVNLSAYASNISVQASNSFSVTWVGTLKPRYSKCFASAGMTKVDGQAYSEHLNYLRMHFVKGKVYFILDLAGGSDPNNYPLVVLNNSFKNGNPAWTWGGSD
>NZ_CP046705|186481:233000|188534_189137_+|WP_114081268.1|DBSCAN-SWA
MIKRIKGLFLTAILTVLFIGVTATHTKAETYLAGEFTITLDDGENGKTYRGCDAQGKCINLENGTSWRDNGYRGITWENGDYTYSVSWRENANEGMYLNIYNKDKQILRRQLVETTENVGTLKGVTYCDVVNITSGQLALRDSQNGQSRGGLDNGNNVLLKKQEGIWAYVSVVQGPNTRINGLSGWVNSNYLHCTKEPID

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_114081709.1|186481_187051_-|transposase	IS630 family transposase	NA	NA	NA	NA
WP_114081708.1|187041_187542_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_114081269.1|188049_188211_+	CopG family transcriptional regulator	NA	NA	NA	NA
WP_114081268.1|188534_189137_+	hypothetical protein	NA	NA	NA	NA
WP_114081267.1|189219_189729_+	hypothetical protein	NA	NA	NA	NA
WP_159402613.1|189885_191108_-|transposase	ISAzo13 family transposase	NA	NA	NA	NA
WP_147262446.1|191205_191847_+	WD40 repeat domain-containing protein	NA	NA	NA	NA
WP_114080591.1|192119_193349_+|transposase	IS200/IS605 family element transposase accessory protein TnpB	D9J0Y9	Brochothrix_phage	3.0e-73	40.6
WP_147262447.1|193456_193924_+	hypothetical protein	NA	NA	NA	NA
WP_114080593.1|194294_194591_+	HU family DNA-binding protein	A0A2H4PAM3	Aphanizomenon_phage	1.4e-16	50.5
WP_114080594.1|194810_195503_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_159402650.1|195596_195761_+	hypothetical protein	NA	NA	NA	NA
WP_114080596.1|195996_196464_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_114080597.1|196935_197679_+	NAD(+)--rifampin ADP-ribosyltransferase	NA	NA	NA	NA
WP_114080598.1|198491_199865_-	DUF2252 domain-containing protein	NA	NA	NA	NA
WP_114081515.1|201576_202599_+|transposase	IS4 family transposase	NA	NA	NA	NA
WP_114081270.1|203056_204169_+	hypothetical protein	NA	NA	NA	NA
WP_114081515.1|205779_206802_-|transposase	IS4 family transposase	NA	NA	NA	NA
WP_114080944.1|206972_207701_+	hypothetical protein	NA	NA	NA	NA
WP_114080945.1|207828_208431_-|transposase	IS630 family transposase	NA	NA	NA	NA
WP_114080946.1|208974_210297_-	MATE family efflux transporter	NA	NA	NA	NA
WP_114080947.1|210599_211124_+	hypothetical protein	NA	NA	NA	NA
WP_114080951.1|211251_211971_-	NAD(+)--rifampin ADP-ribosyltransferase	NA	NA	NA	NA
WP_159402651.1|212006_212267_-	hypothetical protein	NA	NA	NA	NA
WP_114080949.1|212684_213635_-	RpoD/SigA family RNA polymerase sigma factor	F4YCU2	Synechococcus_phage	5.2e-41	34.1
WP_114080950.1|214028_214445_-	hypothetical protein	NA	NA	NA	NA
214613:214637	attL	NA	NA	NA	NA
WP_114081249.1|214816_215788_-	AAA family ATPase	NA	NA	NA	NA
WP_114081251.1|215777_217424_-|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_114081250.1|217710_218550_+|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_159402652.1|218771_218924_+	hypothetical protein	NA	NA	NA	NA
218618:218642	attR	NA	NA	NA	NA
WP_114081254.1|218966_219419_-	DUF1392 family protein	NA	NA	NA	NA
WP_114081253.1|219582_220071_-	TIGR00725 family protein	NA	NA	NA	NA
WP_084227073.1|220195_220471_-	UBP-type zinc finger domain-containing protein	NA	NA	NA	NA
WP_114081252.1|220646_220838_-	hypothetical protein	NA	NA	NA	NA
WP_159402653.1|220936_221077_+	hypothetical protein	NA	NA	NA	NA
WP_114081255.1|221088_221574_+	bleomycin resistance protein	NA	NA	NA	NA
WP_167756041.1|221880_223113_-	hypothetical protein	NA	NA	NA	NA
WP_114080757.1|223196_223445_-	hypothetical protein	NA	NA	NA	NA
WP_114080756.1|224034_224541_-	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	2.5e-10	32.9
WP_114080755.1|224793_224982_+	hypothetical protein	NA	NA	NA	NA
WP_114080754.1|225002_225509_-	hypothetical protein	NA	NA	NA	NA
WP_114080753.1|226583_228224_-	iron uptake porin	NA	NA	NA	NA
WP_114080752.1|229022_229820_+	phosphonate ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.1e-23	35.6
WP_114080751.1|229864_230866_+	phosphonate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_114080750.1|230941_231715_+	phosphonate ABC transporter, permease protein PhnE	NA	NA	NA	NA
WP_167756004.1|231959_233000_+|transposase	IS630 family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage
NZ_CP046705.1|WP_114080757.1|223196_223445_-|hypothetical-protein	223196_223445_-	82 aa aa	NA	NA	NA	186481-233000	yes

Protein sequences of NZ_CP046705.1|WP_114080757.1|223196_223445_-|hypothetical-protein

>NZ_CP046705.1|WP_114080757.1|223196_223445_-|hypothetical-protein
MQEFKSPVSRLVRLFQKGRDSWREKALEKQKKVRALEIKVRDLTASREYWKQRALAAESEIKEQRIGGVSEKKKKMLARTST

Self-targetings in the prophage

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP046705_3	Orphan	3.1|218646|38|NZ_CP046705|CRISPRCasFinder	218646-218683	38	214704-214667	1
NZ_CP046709_1	Orphan	1.1|41593|38|NZ_CP046709|CRISPRCasFinder	41593-41630	38	214704-214667	1
NZ_CP046710_1	Orphan	1.1|39890|38|NZ_CP046710|CRISPRCasFinder	39890-39927	38	214704-214667	1
NZ_CP046715_1	Orphan	1.1|4150|38|NZ_CP046715|CRISPRCasFinder	4150-4187	38	214704-214667	1

1. spacer 3.1|218646|38|NZ_CP046705|CRISPRCasFinder matches to NZ_CP046705 position: 214704-214667, mismatch: 1

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

2. spacer 1.1|41593|38|NZ_CP046709|CRISPRCasFinder matches to NZ_CP046705 position: 214704-214667, mismatch: 1

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

3. spacer 1.1|39890|38|NZ_CP046710|CRISPRCasFinder matches to NZ_CP046705 position: 214704-214667, mismatch: 1

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

4. spacer 1.1|4150|38|NZ_CP046715|CRISPRCasFinder matches to NZ_CP046705 position: 214704-214667, mismatch: 1

ggatgattgcaagcccattgcaaataataatgagtctg	CRISPR spacer
ggatgattgcaagcccgttgcaaataataatgagtctg	Protospacer
****************.*********************

9. NZ_CP046711

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP046711_1

• CRISPR_ID: NZ_CP046711_1
• CRISPR_location: 17185-17252
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP046711_1

Consensus_repeat	Method
TTCGCCCATAACGTTATGGGTAG	CRISPRCasFinder

spacers of NZ_CP046711_1

>1.1|17208|22|NZ_CP046711|CRISPRCasFinder
ATAATTCAATATCACCTTTATC

CRISPR arrays and Neighbor proteins around NZ_CP046711_1

CRISPR arrays

The CRISPR arrays of NZ_CP046711_1

>merge|NZ_CP046711|1|17185-17252|CRISPRCasFinder
TTCGCCCATAACGTTATGGGTAGATAATTCAATATCACCTTTATCGTCGCTGATAGCGTTATTAGTGG

>NZ_CP046711|1|1|17185-17252|CRISPRCasFinder
TTCGCCCATAACGTTATGGGTAG	ATAATTCAATATCACCTTTATC
GTCGCTGATAGCGTTATTAGTGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046711.1|WP_114084589.1|2496_4641_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NZ_CP046711.1|WP_114084599.1|20018_21551_-|relaxase/mobilization-nuclease-domain-containing-protein	unknown	unknown	gnl|CDD|367497
NZ_CP046711.1|WP_114084588.1|636_2454_+|serine/threonine-protein-phosphatase	unknown	unknown	gnl|CDD|223704
NZ_CP046711.1|WP_094345603.1|28458_29193_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046711.1|WP_114084605.1|24636_28182_-|DNA-primase	unknown	unknown	gnl|CDD|378030
NZ_CP046711.1|WP_159402702.1|22719_22896_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046711.1|WP_114084619.1|21525_21936_-|plasmid-mobilization-relaxosome-protein-MobC	unknown	unknown	gnl|CDD|368576
NZ_CP046711.1|WP_114084595.1|13757_16628_-|superfamily-I-DNA/RNA-helicase	unknown	unknown	gnl|CDD|350195
NZ_CP046711.1|WP_114084597.1|17828_18584_-|ParA-family-protein	unknown	unknown	gnl|CDD|224113
NZ_CP046711.1|WP_114084598.1|18878_19739_-|DUF1186-domain-containing-protein	unknown	unknown	unknown
NZ_CP046711.1|WP_114084601.1|22962_23610_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046711.1|WP_114084602.1|23747_23987_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046711.1|WP_159402698.1|8823_9564_-|trypsin-like-serine-protease	unknown	unknown	gnl|CDD|379142
NZ_CP046711.1|WP_159402701.1|11691_11865_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046711.1|WP_114084604.1|24454_24697_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046711.1|WP_159402699.1|9800_10997_-|trypsin-like-serine-protease	unknown	unknown	gnl|CDD|379142
NZ_CP046711.1|WP_114084618.1|7703_8552_+|tyrosine-type-recombinase/integrase	unknown	unknown	gnl|CDD|234698
NZ_CP046711.1|WP_159402700.1|11013_11565_-|hypothetical-protein	unknown	unknown	gnl|CDD|372967
NZ_CP046711.1|WP_114084590.1|4959_7308_-|FHA-domain-containing-protein	unknown	unknown	gnl|CDD|223815
NZ_CP046711.1|WP_114084594.1|13181_13643_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046711.1|WP_114084589.1|2496_4641_+|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	4.11984e-75
NZ_CP046711.1|WP_114084599.1|20018_21551_-|relaxase/mobilization-nuclease-domain-containing-protein	gnl|CDD|367497	pfam03432, Relaxase, Relaxase/Mobilisation nuclease domain. Relaxases/mobilisation proteins are required for the horizontal transfer of genetic information contained on plasmids that occurs during bacterial conjugation. The relaxase, in conjunction with several auxiliary proteins, forms the relaxation complex or relaxosome. Relaxases nick duplex DNA in a specific manner by catalyzing trans-esterification.	1.32648e-18
NZ_CP046711.1|WP_114084588.1|636_2454_+|serine/threonine-protein-phosphatase	gnl|CDD|223704	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms].	2.85988e-63
NZ_CP046711.1|WP_114084605.1|24636_28182_-|DNA-primase	gnl|CDD|378030	pfam08707, PriCT_2, Primase C terminal 2 (PriCT-2). This alpha helical domain is found at the C terminal of primases.	5.24207e-10
NZ_CP046711.1|WP_114084595.1|13757_16628_-|superfamily-I-DNA/RNA-helicase	gnl|CDD|350195	cd18808, SF1_C_Upf1, C-terminal helicase domain of Upf1-like family helicases. The Upf1-like helicase family includes UPF1, HELZ, Mov10L1, Aquarius, IGHMBP2 (SMUBP2), and similar proteins. They are DEAD-like helicases belonging to superfamily (SF)1, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF2 helicases, SF1 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.	1.7058e-30
NZ_CP046711.1|WP_114084597.1|17828_18584_-|ParA-family-protein	gnl|CDD|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	1.29421e-63
NZ_CP046711.1|WP_114084590.1|4959_7308_-|FHA-domain-containing-protein	gnl|CDD|223815	COG0744, MrcB, Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane].	4.66107e-170
NZ_CP046711.1|WP_114084619.1|21525_21936_-|plasmid-mobilization-relaxosome-protein-MobC	gnl|CDD|368576	pfam05713, MobC, Bacterial mobilisation protein (MobC). This family consists of several bacterial MobC-like, mobilisation proteins. MobC proteins belong to the group of relaxases. Together with MobA and MobB they bind to a single cis-active site of a mobilising plasmid, the origin of transfer (oriT) region. The absence of MobC has several different effects on oriT DNA. Site- and strand-specific nicking by MobA protein is severely reduced, accounting for the lower frequency of mobilisation. The localized DNA strand separation required for this nicking is less affected, but becomes more sensitive to the level of active DNA gyrase in the cell. In addition, strand separation is not efficiently extended through the region containing the nick site. These effects suggest a model in which MobC acts as a molecular wedge for the relaxosome-induced melting of oriT DNA. The effect of MobC on strand separation may be partially complemented by the helical distortion induced by supercoiling. However, MobC extends the melted region through the nick site, thus providing the single-stranded substrate required for cleavage by MobA.	0.00943285
NZ_CP046711.1|WP_159402699.1|9800_10997_-|trypsin-like-serine-protease	gnl|CDD|379142	pfam13365, Trypsin_2, Trypsin-like peptidase domain. This family includes trypsin-like peptidase domains.	1.75694e-15
NZ_CP046711.1|WP_114084618.1|7703_8552_+|tyrosine-type-recombinase/integrase	gnl|CDD|234698	PRK00236, xerC, site-specific tyrosine recombinase XerC; Reviewed.	1.26859e-38
NZ_CP046711.1|WP_159402700.1|11013_11565_-|hypothetical-protein	gnl|CDD|372967	pfam14218, COP23, Circadian oscillating protein COP23. This family includes the circadian oscillating protein COP23 from Cyanothece sp. (strain PCC 8801). The levels of this peripheral membrane protein display a circadian oscillation.	2.40232e-28
NZ_CP046711.1|WP_159402698.1|8823_9564_-|trypsin-like-serine-protease	gnl|CDD|379142	pfam13365, Trypsin_2, Trypsin-like peptidase domain. This family includes trypsin-like peptidase domains.	7.95272e-19

Protein sequences

>NZ_CP046711.1|WP_114084595.1|13757_16628_-|superfamily-I-DNA/RNA-helicase
MLESEKLIQIVQAWLGYIRLEELTQAEVERSSDIYSKVVDKGVQLVGNKLLLDSEVFTQFQQQQQAAKRGNKNDVQMAVAFPQIYIINGKGKDQKLKYLPLFTIDISPIFKGNYRKTGWDLTEYEFQPVVVNLMRLYGLEEEQAESLIVASGIGKFLEDTFKGRFPTLRDFLELVDLPQGNYKTSQQPYLLRCDFTPYNALLKQDLQEILKELQQPDCNSEWLTETHPAMQYLWGEPQSPKHEVMFWGAFPSHAPDEFQASVLKHAQENLLTAVCGPPGTGKTEVFLHLIAQQVVNRALRLVQGLDDANNLIFFVGANNSTVKKFQQRLAIDSPAQQFYLPGGNQANIRKSTLPKLQSTQDWLRQTEFDQDSWQQAKLELLQAESEIQQLIEQDRLNTAQKVTDTERRSQLDGEIESLNNDIAAKSAELQALTEQLSSLSDYANFPLDAYQQIREELSQAERELPKESDSITKRALNWLNATTDQRIFRRLALRINAAVLNTLATGHPFQTPLDHPSLTTAQTSVNQKLDFSQQWQNLHRGVTEIQTQLTALNKELELKLFRHQQIEKQIDSYPQGDFYNLFYRDHHQLQVELFQRAWAFLLQEVLRRKESVMRALSTYGSVLTGDGEALLKLESDSDAIYRDLSLIFPVISSTLQSMRNMLPILHPNSVKLALVDEAGTTLIHQLFPLLVRSQQAVVAGDPQQIEPIINLCDDTIKQYLKTAFLDRGMGNEDYYRYAPTAKYTATAYHRAAGASGTEGDLGNGIILSNHYRCTPPIIQFCSPNYPGGLQILSGDQQTATVKHLLAYHVEGSHTHNTNPEEIDAVETIIASLLKHGYSTNSDDNSKTIGVMSPFSQQANALKYRLSNRWRNFSWDDIGTVHTFQGGEKAAIIFSPYQCHQEHSFWFLNRKPNLLNTAVSRARELFILVGNLRELELAGGETKRLVEHIRQHGEIRT
>NZ_CP046711.1|WP_114084594.1|13181_13643_+|hypothetical-protein
MSTNLNHFISARIPSKLDDEVENLAKRKGEKKSKILVNALDHYLKYYEAQEKSEENFSLDSDDKQTINKIEKLVLVIVKKQMQEVQNEFKKEVERLEKLLFEFCSQNTVINNSQNSRLDDQNSRLNEHFSQLEELRSKFKFYMRNPENIQKIQ
>NZ_CP046711.1|WP_159402701.1|11691_11865_+|hypothetical-protein
MSVLEQPDELEVGVGIGVEIVVEGSNTTRIPINKISLILEPWNIATTNTIVKIVTPI
>NZ_CP046711.1|WP_159402700.1|11013_11565_-|hypothetical-protein
MKILHKVSVLAASVTIGLVSNAALTNSPVLAQQVRFACKTVNGAPTTVIKKNEWSSVRQMIRWTLQGATGDYTPQRRCEEVTGRLNQSFTQGSQYITHGIMNKQPVICITDKKGNGCQHLLLTLVNHSNRPNPKAVLNDLFSLNDRNFSSNAPLREGSCSVYVNINALIQGKQVIASEVCTSI
>NZ_CP046711.1|WP_159402699.1|9800_10997_-|trypsin-like-serine-protease
MKCPTFVLVALVCMGGLVLQPSIKTFISLGYAQTTISPVLVSQAEFPVDIIRDKASLITTRVFSVNPQQQEWDNGLILDNSASGTLIARKQIKQDKQSFYIYLVLTNHHVLSRYNSRYYIQTHDGLIHQAHQYSQTKLKNNDLGILWFYSPYEYKKATLGKSSNLKDNSKVFVAGFPCDLSSVEMYCPAKFFFSSGKVFLIDRPLVDGYQIGYTNDTKAGTSGGPVLNGQGQLVGINGRGKDDPASRQYRYPDNSGTPQITQEQSLALGIPIETYLQLAPKKPFNKILPEIKNIKFFNLLYEKNNTFDFSSSESSDFISKELAKYKIIVLVLVILEIFFMLICISKIINQKFNLNSALKKIEQLEKNHESSQELEEKLPEIKEPAKNPPIQEADFESN
>NZ_CP046711.1|WP_159402698.1|8823_9564_-|trypsin-like-serine-protease
MTLLLSISGCSNFPERIKKIAVDTTVFINARGTGTGVIIAQKGNKYYVLTSRHVVGIPPGPIDDKYTLKTFDGIEYLIEYKKVKPDQNLDLAIVEFNANGRTYKTATLSKALKKDSSVYISGWRDCSTPKYEFNKGKVSEIVSYISALPKGSKLEEYNKKDIKEGYKVKYTNITIRGMSGAPVFNDTGNVVAIHGKPGHYKGTLYNFEACNELNDDFANNWGIPIEDFFKSSLASGIKDIKLNIAD
>NZ_CP046711.1|WP_114084618.1|7703_8552_+|tyrosine-type-recombinase/integrase
MTELVEEWLDVHHGKTRASYHNTIRKFLTFTCVDAIADIQIRHVRDWLDFLQEADTTKVKHLNILKAFFSYVTSLEKPPLTRSPIPKQFKLPKPKDTLVERILTPSDVDAMIAATTDKRNRLILKTLYLTGIRVSELCGLRWKDAITSRGGGGQINVYGKGGRTRRVHVPQSLWVELMSLRSEALKDAPVFASATGRPLAPSHIDRVVKRAARAAELENAMNVSAHWFRHSHATHALDEGVPVHLVQATLGHTSLDTTSKYLHVSPDRSSGEVLVKRWSEPF
>NZ_CP046711.1|WP_114084590.1|4959_7308_-|FHA-domain-containing-protein
MALFAELVKALFTWIDSRLSPPIQQTSRTIGSNISQIVTTLVETFPQLKRFARVPKLLVRNPVAGKEKEYPLLHDRFILGRDRRVSDIIVDNPLVSKEHLSIERKNSLPNKPFVIQDRRSQHGIYQGNKKIDREFVLTHGDVLTLGKPEFANSVRIKFLNPPPLHISAAICSGYAILFIPILFLVLSGLAWVICPPVNPLPILERKPSIIYASNFTPLYKRSNLVYKEAKNLSEFPAFLSQAVIASEDSRYYWHQGIDILGVTRAIFINFKRNKFSEGASTLSQQLARTLFDSYVGGQQLNLLRKIKEAGIALKLETQYSKDVILLYYLDNIYLGENVFGFKDAAKVYFGKSVNKLELSEIATLVAMLPAPNGFDLCRNRSDASHKELVDRRNRVINLLLASKKITSEQADLAKIYPIQAAPSFCQYVNTRIAPYFADRVNQELQILLGEGAKRGNFFIQTSLSLEMQKQAERALAKIIDTEGISKGFSQGAITTIDPKTGRILALVGGVDYQRRQFNLVTQAQRQPGSTFKVFAYTTALEQGIRPEKTYSCDKLDWEGEQEPFKPCEHTNKKSLDMYDSIALSENVIALRIAKDVGLDNVVTTATKMGIKSKLRVNIQGKEKAVPRLILGHSEVNLLELTGAYAVLANEGIKTRPHAIKRIFDSSSCKDIQNVSTCRVIYSDNTETESRVLKPEVARTMTRLLTGVVERKDGTGNKANLPGVQVAGKTGTTNRARDLWFVGYMPNQFVTGVWLGNDENTPTSGTSTLAAQVWRDYMSRFIP
>NZ_CP046711.1|WP_114084589.1|2496_4641_+|serine/threonine-protein-kinase
MISIFCSYCSYPNPHSQLNCLSCGALLSFDEVDPNHLFTGTFLKQGQYKIEKTLGQGGFAITYKVIDLNNNSRVVAIKELWPERAGREGSNVRWPYTIPPNERQVQIKKFKEEAQRLLDLVKFNHPSIVKVYEYFEENNTVYIVMEFIDGKTLFKILKEEGVLPEKRVKKYFLQLAYALKIIHGNDILHRDIKPDNIIINHQDRAILIDFGAARDFLSGRSKNMTQILTPGYAPPEQYSPRAIRYPSADIYSLCASMYELLTGELPANASDRTSSKTSTPTGTDSLILPRQLSSHISSLMEKIILTGMKLKAEERFKDADHLIEAFNGNFMSPLFIKARELVKNGKLAEAVQLYERCLLEEPDNSKAAVENALILTYLVNPQAENAVYQAIKLQPNDGRLYGALGLLYCRQSNWQEAIKQLQKGVNLAPHESWIWANLGWALAKCGSLQKSLVAVDKALGLDKNSTFALALKVWIFVNQQQWNSAITLAKQAIWNSQQANSQNIGNLQTWIYPCLIVALDRVPNKSVIELEKCLHEYINQVPDSAFIYGFNGYLQAQQGQWANAIAEFNLGVAKSKVPFWILLNLGISYENEKNLQTAIQVYKSCHHLQSKDFFVLFRLGTILGQEAQRLDKQELWLEARSYLELAVQLKPDYAEVYHNLGWVLHHIRNNNGLIDNPAKILATYRQAVQLYEQQNKSALAQQIRQAFQVLGVQL
>NZ_CP046711.1|WP_114084588.1|636_2454_+|serine/threonine-protein-phosphatase
MTLSSTDFPPILIIKANTCFQIDNFRLEVNNHLGQFADVHYFQVNIHSHEADSNLNDLTLGKPGLLRVGTVDGCLNLERQLRQVIGTNKLVSELLISTIDDWVSINLLEQEPKDDSVNLKQELATDIDQPLESEVSHSQTSSDLDSDLSLTKLEYLEEEFFQPQAVAPEYESPSPKIILLSYLPEPEITLSAWLEQDNPLEISLSLAIQVCQFFQYVYQQGWCFVHINPAFIQVGTPIQFFDLAGIGVVGKKLQYGLTGDYCSSELALGYPVDQQMSTYIIGTLLYQSLHHKLPNIDDNSKLEIKSIPRIYQIINICFASIGEGFTLSQLLSLLRETRQLFSKLKIKWNVASRSTVGLSLSRLENEDSYGIKQDSSNQSEALILAVVADGMGGMAQGEVASKLAVKTVLEEPVSIGLNSVKYGAQWLTNAIQKANDCVVKNVRNGGTTLSLILAIGRELMIAHIGDSRIFLLRNGYICQLSEDHSLVAMLLANGEITYKESQDHPERSVLLRSIGTKRNLSDGYIQDLTRFGSDLSMGLENGDILLICSDGVWDLVSSHELAEIFVNNENLQSLVNETIDKVISRGATDNATILALQCSIEKYYE
>NZ_CP046711.1|WP_114084597.1|17828_18584_-|ParA-family-protein
MSRIIAVFNQAGGVAKTTLTQNLGYQIAQLGHRVLLIDIDPQASLTIFMGLVPRDIEQTVNNAIVDEQPLPIHEGIHGMDLAPANISLSTAEMQLVSASMRDFRLKEAIEPIQENYDFILIDCPPSLGLLSYISLVAATHVLVPLETHFKAFEGTGELLKTVATVRNKPNRKLQIAGFVPTKYDARNSQDTRTLAAITEQLASAGTVFAPIPRSTAFVDASEERMPLAVYEPKHPSVQILKKIAVSLESLK
>NZ_CP046711.1|WP_114084598.1|18878_19739_-|DUF1186-domain-containing-protein
MPRNSYSSPVNQLLDYQPGTGQLSPDEWPDYQELGITAEDIPELIRMATDEDLYNIPDDENDFFGEDSLLEYAPIHAVRALGQLRASSAIEPLISLFPKMDDAFDNEVLFVLAEDLTDVLSLIGLSAIPALAAYLADDSHEESWRVQAIVTIKRITAVYPEHHAQCVAALSFQLESFEENSPELNAHIIWALTDLNAINSLPLIEQAFKAECVDDEVVGDWDDVQKRFGLSSKKSQPPKSIAPTGSHQPAQETVTKEKNEADHERQKKAQQKREARRQRNLKSNGS
>NZ_CP046711.1|WP_114084599.1|20018_21551_-|relaxase/mobilization-nuclease-domain-containing-protein
MIGKQTKGRGFRKLLDYLESREDAKLIGGNMSGRNARELAREFKLSRQLNSDAERVVYHVSLSAAKDDKLDDEKWSEIGDRYMREMGFDANQFVIFRHHNTDDDHIHIAASRIRIDTGLVVHDSWDYVRSEKVLRQIEQDYELVQVQGSREKLNRTPSTGQIRRIIREQEEYSLGKRDTPPERTIKEQIQQTIDRASVDNPQMPTLIMRLQQASVSVRTGWTRNGKSKGISYEKDGQAFSGTQLGAAYTFPGLQKHLGIDYQPERDDEPIHELLLKPVKPLPVEQLEKLFQDIERKQQQPQFTPPPEDKVVWQVLHKYLNEKRYIPDYISQGLHNNQLLYMDEQRNILFIKRNLDGEKTGALIWSKPRENHRAVEYDQNTSTPYGWFYLRLGGQPTDKVENVFLCSTPIDAMSAATYLISSCKGLPPTRTMLIVADDPNNLPMEFLKSFNRVVVAFNNDSEGNNAASAVLELLPQGKRLKTHNPDWSQELEAHLREEQEKQRQQDRGFSL
>NZ_CP046711.1|WP_114084619.1|21525_21936_-|plasmid-mobilization-relaxosome-protein-MobC
MANRKQSKALVRKHIFPVRLSDIELDLLRIKSLDAGMSASELMRRNALMRPLPKRLSKISLQTYWELGQIGNNLNQLVKATNIALKIGRTLPADPQLLRELLELLHQCRRDIASDDVDSEDSEEEDEEDDWEADEG
>NZ_CP046711.1|WP_159402702.1|22719_22896_+|hypothetical-protein
MRRYIEKLTSDKYGYTYDEVSEMLKGLGINLSGGRIKYLLGEVKKSSRRQKKTYSLPN
>NZ_CP046711.1|WP_114084601.1|22962_23610_-|hypothetical-protein
MSELTDGLEYILDWLESTNLELFDCYNPGLTRQQIDKIVKDLPFKLSEEIYELYQWRNGIADLGFNNYYPPVEFLFPNQLFSSLPTSFSTLQDSVSNYYDFWQFEQSNMMDKPFDDYKGWDQKWFPIALFENKRILYVVGDIEPSPVYFIDFIFIENPLRVYKSLTSMISVIAECCELGLYQLIPDESGEEDDMIIRIDEEKLELEKEIYQKYNS
>NZ_CP046711.1|WP_114084602.1|23747_23987_-|hypothetical-protein
MLITESESSPDYLLESVAEVAQVVGTRAMRRVLHFCDIRVRVDLPMTFFRCLPTEVYSNESILRAVASMQQSCNLTVTL
>NZ_CP046711.1|WP_114084604.1|24454_24697_+|hypothetical-protein
MDDDTQELIAIQEELSGISERLRKIFPSTHPQFDSVFEDVGAASYYIREAGYRLESVLTTVQGDSAGSASDAEISETEIE
>NZ_CP046711.1|WP_114084605.1|24636_28182_-|DNA-primase
MSPLQQFNHSVSTQSADAQGANSVALTKLELIESRIIKFAFNATGKNKDWDFKKLAGNFIDVEGTLADVQQHIKAGHAICAGLLGGKWRSKANVIGSQWLLLDIDNSNIARDAYDKPIKDENGNYIKVYDHQLTIEEALAHPFIKKHCALIYTTASHKPEWHKFRLIFLLPEYVQGADTVEACTRFLMQQLPHDPACKDASRVFYGSTEAEFPLVNPEATLPAEWISEAIAIAQQERIEYQQRIQEIESRRKEWREISLTEGWDIDQLIQNALSFIPPRTPGSGNYDECRQVLMALVNHYGASEAEIIAEQWSPSIKGSTWNIHAKIRSFRRGGISIGTLFHIAKQYGFRFPQRQYEPYLPKGVISREQWELGRVREDLSSFQNLLKQAIAPFSSIFKGFKAPPTPKPLPEIDTPSPNVIIYKPGNIPYISEVTGNISISCQPEEHIAAWVEAVSKGWKQILDNSHPGLGKSYNAGQLTAALFGVDKLIYQDANHRNPSTLPIETNFVDLPVRHNGFKLDPTRKTPTGEDFKLWTKAGETADTDGNCHRTYLFNAFRNKNFSSLDFEESGISPICGGCSLKNQCRFAYGDGFGFRFQKRSAIQNYSELRAHPDSTPVTLTNAADQTFTVGRLWEEAGTLIKPVRSVDVNRGDFETTLGKLLLLEPNLLSQLQPALLVLRQLLTQQIKPTDRYGFDDASIRALLPPFPTGLDIEAIRQASEPDLTFLEDLDSIDITQDKQLKKSSAARYAAKKVVKDSARTAGREFLDLPNYWLPDFLEAWKGDGSFESQWGVLSIYRRNPKHTELAKSAQFNIYLDATFKSQQLKLKLGIDEPVLVIEQQRPDYGNLKVVNVTGLGKLPKNRSLPLSARVNALKETLKKLCPNLGIIDWKQIASQAEGRTEYGHFVDGRGVNRFSECDAIASFGIPYQNIGVLAAQYQVMTGEPVNLEDKNSAFQKYLTDLIRAEIIQEIGRLRAHRRPNVELTFYFCADYDLSFLLDELPGIKLEVVDACSICTEAGSRDQQTGHAIVKAFTQLWQSHQKIGQKAIAKIIDTTQGWVSRFTQRWGGWQHFKKLLLLLLDSLNSGSNKNLAELTDDEKWLARTYFPMLIAESESSLPTSLDGIAEVTEVLGSTAMRRVLHRCSSQVRASLLMIVLSCLPTEVYSISVSEISASLAEPALSP
>NZ_CP046711.1|WP_094345603.1|28458_29193_-|hypothetical-protein
MSPMLTVKDLTSDFQLPLHNEAAFEKIREAKDYASTQALAAGAAALATGGIIHPAGWVLFGLAYKPLVVTQKLARLEKLGTLLFDEFKSLDVQVFPVIPVEDNNPIDLFIRFPRTTHLFISIRSKGDREIVYNEAREVLQVKRKDKNGLKLWQPCPLVELADYEKWLNKNRDKFLMSSREAQKTPTAKVLVLWPPTKAANTHNEHLYSEVGSMKILALRRKGTAFVIQEEEVTEFVRAWLAKYR

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP046711_1	1.1|17208|22|NZ_CP046711|CRISPRCasFinder	17208-17229	22	NZ_CP046711	Nostoc sp. ATCC 53789 plasmid pNsp_h, complete sequence	17208-17229	0	1.0
NZ_CP046711_1	1.1|17208|22|NZ_CP046711|CRISPRCasFinder	17208-17229	22	GU071101	Prochlorococcus phage P-HM1, complete genome	64681-64702	2	0.909
NZ_CP046711_1	1.1|17208|22|NZ_CP046711|CRISPRCasFinder	17208-17229	22	MN995824	UNVERIFIED: Enterococcus phage EFP1, complete genome	36804-36825	3	0.864
NZ_CP046711_1	1.1|17208|22|NZ_CP046711|CRISPRCasFinder	17208-17229	22	MT747435	Enterococcus phage AE4_2, complete genome	36811-36832	3	0.864

1. spacer 1.1|17208|22|NZ_CP046711|CRISPRCasFinder matches to NZ_CP046711 (Nostoc sp. ATCC 53789 plasmid pNsp_h, complete sequence) position: , mismatch: 0, identity: 1.0

ataattcaatatcacctttatc	CRISPR spacer
ataattcaatatcacctttatc	Protospacer
**********************

2. spacer 1.1|17208|22|NZ_CP046711|CRISPRCasFinder matches to GU071101 (Prochlorococcus phage P-HM1, complete genome) position: , mismatch: 2, identity: 0.909

ataattcaatatcacctttatc	CRISPR spacer
ataattcaatatcacctgtata	Protospacer
***************** *** 

3. spacer 1.1|17208|22|NZ_CP046711|CRISPRCasFinder matches to MN995824 (UNVERIFIED: Enterococcus phage EFP1, complete genome) position: , mismatch: 3, identity: 0.864

ataattcaatatcacctttatc	CRISPR spacer
ataattcaatatcacctttgct	Protospacer
*******************...

4. spacer 1.1|17208|22|NZ_CP046711|CRISPRCasFinder matches to MT747435 (Enterococcus phage AE4_2, complete genome) position: , mismatch: 3, identity: 0.864

ataattcaatatcacctttatc	CRISPR spacer
ataattcaatatcacctttgct	Protospacer
*******************...

10. NZ_CP046703

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP046703_1

• CRISPR_ID: NZ_CP046703_1
• CRISPR_location: 724575-724677
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP046703_1

Consensus_repeat	Method
TAAAGCCCCTAAATTTATTTATG	CRISPRCasFinder

spacers of NZ_CP046703_1

>1.1|724598|57|NZ_CP046703|CRISPRCasFinder
AATAAAGATAAAAAGTGTATTTTGAGACGCGCAGCGCAAAAAATACAGCGTCTATTA

CRISPR arrays and Neighbor proteins around NZ_CP046703_1

CRISPR arrays

The CRISPR arrays of NZ_CP046703_1

>merge|NZ_CP046703|1|724575-724677|CRISPRCasFinder
TAAAGCCCCTAAATTTATTTATGAATAAAGATAAAAAGTGTATTTTGAGACGCGCAGCGCAAAAAATACAGCGTCTATTATAAATCCCCTAAATTTATTTATG

>NZ_CP046703|1|1|724575-724677|CRISPRCasFinder
TAAAGCCCCTAAATTTATTTATG	AATAAAGATAAAAAGTGTATTTTGAGACGCGCAGCGCAAAAAATACAGCGTCTATTA
TAAATCCCCTAAATTTATTTATG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046703.1|WP_114086003.1|741348_741627_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114086006.1|733742_736595_-|CHASE2-domain-containing-protein	unknown	unknown	gnl|CDD|226703
NZ_CP046703.1|WP_114080583.1|716085_716334_-|hypothetical-protein	unknown	unknown	gnl|CDD|381104
NZ_CP046703.1|WP_114086010.1|721411_721789_-|response-regulator	unknown	unknown	gnl|CDD|381104
NZ_CP046703.1|WP_114086009.1|726609_728373_-|WD40-repeat-domain-containing-protein	unknown	unknown	gnl|CDD|238121
NZ_CP046703.1|WP_114086007.1|732402_733746_-|response-regulator	unknown	unknown	gnl|CDD|381147
NZ_CP046703.1|WP_114086012.1|731766_732243_+|DUF1499-domain-containing-protein	unknown	unknown	gnl|CDD|226854
NZ_CP046703.1|WP_114086013.1|730611_731064_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114086004.1|738136_740689_-|CHAT-domain-containing-protein	unknown	unknown	gnl|CDD|227328
NZ_CP046703.1|WP_114080585.1|712944_714609_-|response-regulator	unknown	unknown	gnl|CDD|381126
NZ_CP046703.1|WP_114080584.1|714673_714883_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114080582.1|716529_717048_+|phycocyanin-subunit-beta	unknown	unknown	gnl|CDD|271301
NZ_CP046703.1|WP_114080580.1|717840_719109_-|hypothetical-protein	unknown	unknown	gnl|CDD|131231
NZ_CP046703.1|WP_114080581.1|717192_717678_+|phycocyanin-subunit-alpha	unknown	unknown	gnl|CDD|271303
NZ_CP046703.1|WP_114080586.1|711506_712913_-|cyclic-nucleotide-binding-domain-containing-protein	unknown	unknown	gnl|CDD|340419
NZ_CP046703.1|WP_114086008.1|729520_730381_-|sulfurtransferase	unknown	unknown	gnl|CDD|225450
NZ_CP046703.1|WP_114086005.1|736818_737871_-|DUF928-domain-containing-protein	unknown	unknown	gnl|CDD|368720
NZ_CP046703.1|WP_114086011.1|721067_721256_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114080588.1|715551_715944_-|response-regulator	unknown	unknown	gnl|CDD|381104
NZ_CP046703.1|WP_012407328.1|728785_729181_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046703.1|WP_114086006.1|733742_736595_-|CHASE2-domain-containing-protein	gnl|CDD|226703	COG4252, COG4252, Predicted transmembrane sensor domain [Signal transduction mechanisms].	9.67257e-129
NZ_CP046703.1|WP_114080583.1|716085_716334_-|hypothetical-protein	gnl|CDD|381104	cd17552, REC_RR468-like, phosphoacceptor receiver (REC) domain of Thermotoga maritima response regulator RR468 and similar domains. Thermotoga maritima RR468 (encoded by gene TM0468) is the cognate response regulator (RR) of the class I histidine kinase HK853 (product of gene TM0853). HK853/RR468 comprise a two-component system (TCS) that couples environmental stimuli to adaptive responses. This subfamily also includes Fremyella diplosiphon complementary adaptation response regulator homolog RcaF, a small RR that is involved in four-step phosphorelays of the complementary chromatic adaptation (CCA) system that occurs in many cyanobacteria. Both RR468 and RcaF are stand-alone RRs containing only a REC domain with no output/effector domain. The REC domain itself functions as an effector domain. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	4.38696e-08
NZ_CP046703.1|WP_114086010.1|721411_721789_-|response-regulator	gnl|CDD|381104	cd17552, REC_RR468-like, phosphoacceptor receiver (REC) domain of Thermotoga maritima response regulator RR468 and similar domains. Thermotoga maritima RR468 (encoded by gene TM0468) is the cognate response regulator (RR) of the class I histidine kinase HK853 (product of gene TM0853). HK853/RR468 comprise a two-component system (TCS) that couples environmental stimuli to adaptive responses. This subfamily also includes Fremyella diplosiphon complementary adaptation response regulator homolog RcaF, a small RR that is involved in four-step phosphorelays of the complementary chromatic adaptation (CCA) system that occurs in many cyanobacteria. Both RR468 and RcaF are stand-alone RRs containing only a REC domain with no output/effector domain. The REC domain itself functions as an effector domain. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	8.08674e-71
NZ_CP046703.1|WP_114086009.1|726609_728373_-|WD40-repeat-domain-containing-protein	gnl|CDD|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	5.57438e-80
NZ_CP046703.1|WP_114086012.1|731766_732243_+|DUF1499-domain-containing-protein	gnl|CDD|226854	COG4446, COG4446, Uncharacterized protein conserved in bacteria [Function unknown].	7.52472e-69
NZ_CP046703.1|WP_114086004.1|738136_740689_-|CHAT-domain-containing-protein	gnl|CDD|227328	COG4995, COG4995, Uncharacterized protein conserved in bacteria [Function unknown].	7.58904e-150
NZ_CP046703.1|WP_114080585.1|712944_714609_-|response-regulator	gnl|CDD|381126	cd17595, REC_TrxB, phosphoacceptor receiver (REC) domain a fused response regulator with a thioredoxin reductase output domain. This family is composed of uncharacterized fusion proteins containing a REC domain and a thioredoxin reductase domain. Thioredoxin reductase catalyzes the reduction of thioredoxin and is thus a central component in the thioredoxin system. Fusion proteins containing REC and thioredoxin reductase domains could play an important role in the environmental regulation of the cellular dithiol-disulfide ratio. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	1.33573e-85
NZ_CP046703.1|WP_114086007.1|732402_733746_-|response-regulator	gnl|CDD|381147	cd19920, REC_PA4781-like, phosphoacceptor receiver (REC) domain of cyclic di-GMP phosphodiesterase PA4781 and similar domains. Pseudomonas aeruginosa cyclic di-GMP phosphodiesterase PA4781 contains an N-terminal REC domain and a C-terminal catalytic HD-GYP domain, characteristics of RpfG family response regulators. PA4781 is involved in cyclic di-3',5'-GMP (c-di-GMP) hydrolysis/degradation in a two-step reaction via the linear intermediate pGpG to produce GMP. Its unphosphorylated REC domain prevents accessibility of c-di-GMP to the active site. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	2.90388e-55
NZ_CP046703.1|WP_114080582.1|716529_717048_+|phycocyanin-subunit-beta	gnl|CDD|271301	cd14768, PC_PEC_beta, Beta subunits of phycoerythrin and phycoerythrocyanin; phycobilisome rod components. phycobilisomes (PBSs) are the main light-harvesting complex in cyanobacteria and red algae. In general, they consist of a central core and surrounding rods and function to harvest and channel light energy toward the photosynthetic reaction centers within the membrane. They are comprised of phycobiliproteins/chromophorylated proteins (PBPs) maintained together by linker polypeptides. PBPs have different numbers of chromophores, and the basic monomer component (alpha/beta heterodimers) can further oligomerize to ring-shaped trimers (heterohexamers) and hexamers (heterododecamers). Stacked PBP hexamers form both the core and the rods of the PBS; the core is mainly made up by allophycocyanin (APC) while the rods can be composed of the PBPs phycoerythrin (PE), phycocyanin (PC) and phycoerythrocyanin (PEC).	1.25646e-97
NZ_CP046703.1|WP_114080580.1|717840_719109_-|hypothetical-protein	gnl|CDD|131231	TIGR02176, pyruvate_flavodoxin/ferrodoxin_oxidoreductase, pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric. This model represents a single chain form of pyruvate:ferredoxin (or flavodoxin) oxidoreductase. This enzyme may transfer electrons to nitrogenase in nitrogen-fixing species. Portions of this protein are homologous to gamma subunit of the four subunit pyruvate:ferredoxin (flavodoxin) oxidoreductase.	0
NZ_CP046703.1|WP_114080581.1|717192_717678_+|phycocyanin-subunit-alpha	gnl|CDD|271303	cd14770, PC-PEC_alpha, Alpha subunits of phycoerythrin and phycoerythrocyanin; phycobilisome rod components. phycobilisomes (PBSs) are the main light-harvesting complex in cyanobacteria and red algae. In general, they consist of a central core and surrounding rods and function to harvest and channel light energy toward the photosynthetic reaction centers within the membrane. They are comprised of phycobiliproteins/chromophorylated proteins (PBPs) maintained together by linker polypeptides. PBPs have different numbers of chromophores, and the basic monomer component (alpha/beta heterodimers) can further oligomerize to ring-shaped trimers (heterohexamers) and hexamers (heterododecamers). Stacked PBP hexamers form both the core and the rods of the PBS; the core is mainly made up by allophycocyanin (APC) while the rods can be composed of the PBPs phycoerythrin (PE), phycocyanin (PC) and phycoerythrocyanin (PEC).	2.09532e-87
NZ_CP046703.1|WP_114080586.1|711506_712913_-|cyclic-nucleotide-binding-domain-containing-protein	gnl|CDD|340419	cd16943, HATPase_AtoS-like, Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS. This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.	5.61696e-36
NZ_CP046703.1|WP_114086008.1|729520_730381_-|sulfurtransferase	gnl|CDD|225450	COG2897, SseA, Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism].	5.5502e-77
NZ_CP046703.1|WP_114086005.1|736818_737871_-|DUF928-domain-containing-protein	gnl|CDD|368720	pfam06051, DUF928, Domain of Unknown Function (DUF928). Family of uncharacterized bacterial protein.	1.01597e-77
NZ_CP046703.1|WP_114080588.1|715551_715944_-|response-regulator	gnl|CDD|381104	cd17552, REC_RR468-like, phosphoacceptor receiver (REC) domain of Thermotoga maritima response regulator RR468 and similar domains. Thermotoga maritima RR468 (encoded by gene TM0468) is the cognate response regulator (RR) of the class I histidine kinase HK853 (product of gene TM0853). HK853/RR468 comprise a two-component system (TCS) that couples environmental stimuli to adaptive responses. This subfamily also includes Fremyella diplosiphon complementary adaptation response regulator homolog RcaF, a small RR that is involved in four-step phosphorelays of the complementary chromatic adaptation (CCA) system that occurs in many cyanobacteria. Both RR468 and RcaF are stand-alone RRs containing only a REC domain with no output/effector domain. The REC domain itself functions as an effector domain. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	1.53245e-45

Protein sequences

>NZ_CP046703.1|WP_114086010.1|721411_721789_-|response-regulator
MTKKLLIVDDEERIRELVQACLEDLGGWDTLTAASGEEGLKIAQTEPIDAILLDVSMPDMDGFAVYEKLQANSATQAIPVIFLTAKVQASDRVRFAQIGIAGVITKPFEPTSICEEVTEILGWDD
>NZ_CP046703.1|WP_114086011.1|721067_721256_-|hypothetical-protein
MQVNALALQVNVLALQVHAFTLQVDALALQVHALALQVDALTLQVDALAFLPNSDDKLQTII
>NZ_CP046703.1|WP_114080580.1|717840_719109_-|hypothetical-protein
MNNRSFATIDGNEAVAQVVYRLNEVITYSLTSSSPMAEWVDAWANEGKRNIWGTVPSVVQMQSEAGVAGNVHDALQTGSLTTTFTASQALLLMLPNMYKIAREFTPTVFHIAARSLAAQALSIFGDHSDVMAARETGFAMLCAASVQEAQDFALIATRATLESQIPFLHFFDGFRTSHEIDKVETLTDDDLREFTPNELIFAHRSRTLTSNKPVLRGRTQNPEVYFQASKTVNPYYLACPDITQKVMDEFAAMTGRQYQLFEYHGDPEAERVIVLMGSGCEAVHEIVNYLNTLDQKVGVLKVKLYRPYDAKCFVAALPETTRNIAVLDCIKEPGASGEPLYLDVVAAIHESWGVGEQKSRGSEVKLELDSPLPLRSSASLPKIIGGRYGLSSKEFTPAMIKAIFENLAPTQRKKRVTQGKRI
>NZ_CP046703.1|WP_114080581.1|717192_717678_+|phycocyanin-subunit-alpha
MKTQLTEAVGSADSQGRYLGNVELQIAFGRLRLATADLEAAKQLGLKAQQLAEGAANAVYQKFPYTTTMQGNNYASDGRGKAKCLRDIGYYVRIIQYCLIAGGTGPADDYMLAGLAEMHSSFELVPSWYAEALKYIKANHGLTGDPGLEINSYIDYIINAL
>NZ_CP046703.1|WP_114080582.1|716529_717048_+|phycocyanin-subunit-beta
MLDAFTKVVSQADTRGQLVSNEQIDALLAVVKDGAKRTDVVNRITSNSSAIVTNAARALFAEQPQLIAPGGNAYTNRRVSACMRDMDIILRYVTYAMFLGDSSVLDDRCLNGLRETYLALGVPGPSTGISIIKMKEAAIAIANDRNNIQPGDCSSLMAELSSYFDRAAAAIS
>NZ_CP046703.1|WP_114080583.1|716085_716334_-|hypothetical-protein
METAFRTENSAVHLLPLAAIFVSLILFFTLELFQKCYIRHHFLADSRDRTRFPQIGIAGVITKPFKPNSIYKEVTEILDWDN
>NZ_CP046703.1|WP_114080588.1|715551_715944_-|response-regulator
MSKTILLIDDELNVREIVKLCLQDLAGWNVVTADSPLEGLQSAVRDSPDAIVLDISIRDTASFELINKIRNNPETQAIPVVLLSAKVRWLNSQILRQYEVAGVILKPFDPVTLPAQIATLLDWDFTSLIN
>NZ_CP046703.1|WP_114080584.1|714673_714883_-|hypothetical-protein
MAEHPFHDQLSLEEQAEKLGKQAVSLGLIPSFVVHYFPDTWVFYIPNESQSEALTPEEAYFRLKQLVKQ
>NZ_CP046703.1|WP_114080585.1|712944_714609_-|response-regulator
MAKPAILTVDDDPEVLQAVSRDLRHQYGDRFRIVRADSGITALDAVQQLKLRNEAVALFLVDQRMPQMGGVEFLEQAKVIFPDAKRALLTAYADTDAAIKSINSARLDYYLLKPWNPPEERLYPVLDDLLDDWLAGFRPPFEGIRVIGNRWSPFSHQVKDFLARNQIPYKWLDIELEPDAAKLIEYAQADGRQQLPLVLFPDGSRLIQPSNLEIAAKIGLQTQAERPFYDLAIVGAGPAGLAAAVYGASEGLSTVLIEREAPGGQAGTSSRIENYLGFPVGLSGSDLARRGVTQARRFGVEILTPQVVTGVKLQDPYRVLQLADGSEISCHALLVATGVSYRWLNVPGAEKLTGAGIYYGAAMTEAIACSNEEVYLIGGANSAGQAAMHFSKYASKVIMLVRGESLSLSMSQYLIDQIAATANIQVCTGCSVVEVKGDEHLEEIVIAHAKTGQTQTVPARSLFIFIGAIPKTDWLDGIIRRDTQGFIVTGPDLTQNGKSPLGWPLERSPFLLESNVPGIFAAGDVRSGSIKRVASGVGEGSIAIQFVHRYLSNV
>NZ_CP046703.1|WP_114080586.1|711506_712913_-|cyclic-nucleotide-binding-domain-containing-protein
MLCIEELINLDPFQQLSQEQLEWVCDRAQTVELSGGEVLSHEGDPACRLFILVKGKINITRRSEGVEIPIGQHEAPSFFGEIPVLTDEPAPVTMRALTNCHLYQLKGEDFRKLLHECRNFERMVFRIMERRMRGLESFIRGREKMAALGTLAAGLAHELNNPASALVRTLGEMPAAILELQRMNLVYGQRNVEEAHTQDWLRIRDQGYDAILNNRLDPVTLSDRENVLLEWLEDYGVKQAWKLAEPLAEGGVEVETLDKMMERWRNDETELREMGLHWLSLSFEVMSMIKHGLRGAERISELVQAMKSYSYLDQGVQQEVDVHQGLEDTLRLFVHKLKCGIQVQRNYEQHLPKILAYGSELNQVWTNLIDNAIDAMDGKGLLEITTHHCDRFAHIDIIDSGSGIPPEIKTRIFEPFFTTKSVGRGSGLGLETVRRIVENRHHGTLSFESQPGRTCFTICLPKSAPLGN
>NZ_CP046703.1|WP_114086009.1|726609_728373_-|WD40-repeat-domain-containing-protein
MDWISLLKFQQADFLQRVKKPKTYDLSLLESQVKGCHTEMMAFWGEPLARLQEFSRQQAEVLAKNPPPTPPEYPEPPDWTIPFPKYFQRQAEDYLLREKIVDLVIAERLGKLVKKVSQDTLQNMILDDEGNLCGESKFSYVLKDNPQLSVQVYVADGESFNGIKKDKIKWSVTQEDLKNHQVLIFLCLFYPSTGQLGYERQSIITGFLPANQIELTEPKLYISPSNLLYAGGLSWYLESLIGKKDTSPVINEKAIADTIQTLPPEHCLKGIVGDWECWQTLQGHNRGINCLAFSFACKNGKALPILASGSRGETKLWDLSKGELIDTLSEYPWVIPGLVDEVNSLAFSSDGQTLVSCGADSTIKLWHVGALDLIDILHKHNGVVRCAAFTPDGRMLATGGDDRKILFWDLMHRQVTIALSLDDTAAHSLVLSRDGETIVTGSYRKIKVWRTSPQTGIKSLKDAQPLHTLMGHSHIVRSLAISADAKLLVSGSWDQTIKIWQLETGELLHTLKGHRDKVYAIALSPDGQIIASGSADKTIKLWHLQTGELLGTFTGHGNIVTALAFTASGDMLVSGSLDKTIKIWQRS
>NZ_CP046703.1|WP_012407328.1|728785_729181_-|hypothetical-protein
MAKKSQPNVEQYQDVRLSATTRIWVITVAILGVCVPLSAVTRSGAILPLVAIGGAAVGTVAVWRSDEQKSKTNYLQQQQIELLERRLANLETIVSSDDLNLQMKIKQIEARDTFGDSSDVSTIPRQPKRKG
>NZ_CP046703.1|WP_114086008.1|729520_730381_-|sulfurtransferase
MNTKALISPQELTSILAEKSSRAVIIDTRTPEDYAISHIPQSINIRDFFTYLLESSYPAGLKELQEYFAEIMSKLGISGAERLIVYEDTLNKGYGQSCRAAFLLKYLGCAEVCILHGGYRAWLTEGLPTTDEVPLCESSIFRLHPNTEMMVTTAEMLQAIDNPAIIKLDVRDRNEWLGLSSSPYNPDFCPRKGRIPNAVWLEWHHLMNSESEIPTFRSPDEIREICQSVGITPESIVYIYCFKGSRAANTLIALEQVGISARNYFGSWNEWSRDFSLPIDSRVISV
>NZ_CP046703.1|WP_114086013.1|730611_731064_-|hypothetical-protein
MAINYRERIITLWAVFLLGTLFHTQLGLMPLFHGLSVIESQKATTINDISGIMWLMLGFFVLPMLAIILTIFTDSKRYRIIHFGLTVFYSIMNLLHVILDLFVQPVLWYQIALMVLLFFVGLLLNITAFKWMQMHNRSNRSQIQLESSRL
>NZ_CP046703.1|WP_114086012.1|731766_732243_+|DUF1499-domain-containing-protein
MRYVQRLMWSIIFVIFFSLTSSFILPAATWAATSGLGVDNIHLAPCPPSPNCAVSQDADSKHSIDPIAYHVDLQTARATLLKVLSVVPRTEVIQQTDNYIHALSKSRIFQFVDDVEFYFPANESVIHLRSASRLGDSDFGVNRRRLEQIRLALRDLKI
>NZ_CP046703.1|WP_114086007.1|732402_733746_-|response-regulator
MMIESLLKPMHILLVDDNPNNLKVLSEAIQGCGWKTLMATDGESAIEQTEYSAPDLILLDVMMPGIDGFETCRRLKANSITQNIPIIFMTALADATDKVKGLEIGAVDYITKPFQQEEVIARLKLHLKISYLTRTLEQRVQERTAELTQSLQQLQNTQLQLIQSEKMSTLGQLIAGIGHEINNPIGFISGNCSHIEEYVKDLLRLVNLQQQKLPHPDPEIEELVEEIDLEYLVEDLPKILGSMDQGIGRLKDISLSLRTFARSDISSMVEFQIHEGIDSTLMLLKHRLKDQGERSVIEVVKQYGELPPITCYPGQLNQVFMNIIANAIDAFDDLYQNRSVEEIAAASPHTITIATSIQHEQQTVTICIEDNALGMPPEVQARVFEPSFTTKPVGKGTGLGLAISYQIIIDKHNGQINCSSTSGQGTKFIITLATSVDRKKISAIALG
>NZ_CP046703.1|WP_114086006.1|733742_736595_-|CHASE2-domain-containing-protein
MWRRFQTFIQHTRSVLIITPTVALTVIVGQSLGFFNLPEWKIRDEWVRQRCQRPATPTQETIADEIVVVTIDERDIQSVRKWPIPDWALAKLLEKIRAQQPRAIGLDLYRDLPEGSGHEELVKIFRSTPNLIGVEKITGERVNPAPELKKLNQVGLADLVLDGDRFVRRALLTAVDAKEQNTLKAGLATLVALKYLEAEKITLESIDPKQQKFQLGKAIYLPLDNQEAGYSDADLGGYQILLNWHGSEAAFRTVSMRDVLAGKIPANLMRDRMVFIGSAAASTNDFFNTPFSSSWISAQKTMPGVVVHANIAHQLVQGAKTGKTNLYGFSGGAVSLWIIFWSAIGSSGSWFLSSRRMRIPGGKILWATIGICGLFVGGGYGMFLHGILIPVTPALAAFISSVIATTNAYKQRRLEEANQQLEIANAQLLDYSKTLEFKVEERTHELLEAKQAADAANEAKSEFLANMSHELRTPLNGILGFAQVLEVSPNMTEKNLEGVSIIYQCGTHLLMLINDILDLSKIEARKLELVTTNVHLHTFLHGVTEICSIRAKQKGISFNILISDRLPVAIEVDEKRLRQVLINLLGNAIKFTDTGSVTFKVDVMSHSSLVIDQELKPMTNDNGQMTHQKIRFQIEDTGIGMSPDQLEKIFLAFEQVGEAGRKSEGTGLGLAISQRIAALMGSQIQVQSHLGEGSLFWLDLIVPVPVSHDWQIEAISTTSVAAALTHQKITGIRGTAPQILIVDDDTNHCSMLISLLQEIGCRTLEASDGKYALQMVTEHHPDVILLDLAMPNMDGFELMVHLQENPQTRFIPIIVSSASVFEENRQRSFQAGATAFLPKPLQIDELFNALKSLLKVEWIYDQSIPQKSFYQSEQKADAELVLPSPDVLQQLYHLAMMGDIPAIEEIIKELTKQDSQLTPFVHELSKFTANFQTGKIRKFLKSFVTTESRQ
>NZ_CP046703.1|WP_114086005.1|736818_737871_-|DUF928-domain-containing-protein
MKRRYLASTLSVIALFTSTTLNSANAVTFTPPINNGAPNQATGGASRGNFFIPASSKSAPSQATGGASRGSLFTPSAGKSAPRQATGGASRGNLFTPSVGKSAPRQATGGASRGDLFTPNAGKGTPRQATGGASRGELFTPSAEKNAPQQASGGASRVGTYYLNPSTVGAAGPAALIALLPQSFYGTTVSERPTILVYIPASNAEEAVFSLKDEAGNTQYQMTIPVALKAGVVAVKLPAEAPALAVGKNYHWFLAVKLDGQLGPNTPYVDGWIQRIKPNAELTTAMEQKDALKRAAAFGKHGVWYDCVETLAALHSTQPSNVTLNKQWEELLSSVSLKEIVTAPLLVSTK
>NZ_CP046703.1|WP_114086004.1|738136_740689_-|CHAT-domain-containing-protein
MAFPIKERRWLYIGLSILSLCLAVTITPVKASVQVSAKSTLNTPASTNQIEQGRNLYRSGHFAEAVMIWQTAAQGYHTQGDRLNEALSLSYLSLAQQELNQWKAAEESIEQSLKLLQTSIPSADAILWAQALNTKANLQLHNGKAETALESWQQAQKYYDLAGDKMGSLGSQINQAQALQSLGFYRRSKQQLEELNQKLGAMPDSEIKVSGLRSLGLALLMIGDSGKSQQVLEQSLAIARKIETTPQLSSILLSLGKTAADLKDPKAALDYFEQAEQVATNPGDRLQARLGHFKLFLDYDKPELATPLAPQLLKQLTELPPSHTSLYAAINFVASLNRQSNSSQIIPMKDLAQLMAVTVKSAQQIQDAQAEAYALHQWGKLYRRTQQLSQAQELTQKSLNIARQLQAEDIIAQSAWQVGQLYKEQGDRPEAITAYTEAVKALKSIRGDLVSVNPDVQFSFRESVEPVYRELVGLLLDQQPSQAELMEARDLIEALQVAELDNFFREACLDISQQIDQIDPNATVVYPIILPDRLAVILSKTGQPLRYYVTQKSQADIEQTLEKLLVALNPVSNSKERDRLSQEIYSWLIRPAEMDQAFKDTQTLVFVLDGRLRNIPISALYDGKQYLIEKYAVALSPGMQLMSARSLQANHINAIVGGISQPRNGFSALPAVELEVKQISKAVRSSMLLNQQFTSQALASRVKSSSADIVHLATHGQFSSRLEDTFLLTWDGEVNVKELSELLKNRGGESSKAIELLVLSACDTAAGDDRAVLGLAGLAVKSGARSTIATLWPVKDKAAEMLMTRFYEQLRQPKITKAEALRQAQINLIRQTDFRDPFFWSAFVLVGNWL
>NZ_CP046703.1|WP_114086003.1|741348_741627_+|hypothetical-protein
MENTLIDKTFRDSDGKIVLAQMPNLPLIVWIVTSLLALIFTNGKINTVLDVVANGSLFTWAWLELFQGVNYFRRALGLAVLIGIIALKIQYS

Crispr_ID: NZ_CP046703_2

• CRISPR_ID: NZ_CP046703_2
• CRISPR_location: 866872-866971
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: RT

Consensus repeat of NZ_CP046703_2

Consensus_repeat	Method
TCGATTATGAGTCGATTGCTCTACCA	CRISPRCasFinder

spacers of NZ_CP046703_2

>2.1|866898|48|NZ_CP046703|CRISPRCasFinder
GTGAGCTAACTTCCTGGAGTTTGATACAGGAATCGAACCTGTGACCTT

CRISPR arrays and Neighbor proteins around NZ_CP046703_2

CRISPR arrays

The CRISPR arrays of NZ_CP046703_2

>merge|NZ_CP046703|2|866872-866971|CRISPRCasFinder
TCGATTATGAGTCGATTGCTCTACCAGTGAGCTAACTTCCTGGAGTTTGATACAGGAATCGAACCTGTGACCTTTCGATTATGAGTCGATCGCTCTACCA

>NZ_CP046703|2|2|866872-866971|CRISPRCasFinder
TCGATTATGAGTCGATTGCTCTACCA	GTGAGCTAACTTCCTGGAGTTTGATACAGGAATCGAACCTGTGACCTT
TCGATTATGAGTCGATCGCTCTACCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046703.1|WP_114083668.1|869454_870411_+|Red-carotenoid-binding-protein	unknown	unknown	gnl|CDD|370323
NZ_CP046703.1|WP_114083672.1|862892_864428_-|slipin-family-protein	unknown	unknown	gnl|CDD|259816
NZ_CP046703.1|WP_114083667.1|871333_871756_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_147262537.1|854922_855039_-|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|350312
NZ_CP046703.1|WP_114083663.1|876231_876516_-|DUF433-domain-containing-protein	unknown	unknown	gnl|CDD|225291
NZ_CP046703.1|WP_114083671.1|865344_866439_-|RNA-directed-DNA-polymerase	RT	pfam00078_RT_CAS-I:CAS-III	gnl|CDD|239569
NZ_CP046703.1|WP_114083665.1|874604_875144_+|DUF2267-domain-containing-protein	unknown	unknown	gnl|CDD|227789
NZ_CP046703.1|WP_147262539.1|855812_855905_-|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|350312
NZ_CP046703.1|WP_114083729.1|872722_873370_+|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|225136
NZ_CP046703.1|WP_114083675.1|856217_856475_+|bacteriocin	unknown	unknown	gnl|CDD|275012
NZ_CP046703.1|WP_114083664.1|875378_875843_-|SMI1/KNR4-family-protein	unknown	unknown	gnl|CDD|378155
NZ_CP046703.1|WP_114083666.1|873511_874309_-|dienelactone-hydrolase-family-protein	unknown	unknown	gnl|CDD|223489
NZ_CP046703.1|WP_114083676.1|855294_855582_-|type-II-toxin-antitoxin-system-HigB-family-toxin	unknown	unknown	gnl|CDD|378301
NZ_CP046703.1|WP_114083670.1|867431_868010_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114083669.1|868176_868842_+|TraX-family-protein	unknown	unknown	gnl|CDD|368639
NZ_CP046703.1|WP_114083677.1|855061_855295_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_159402445.1|870579_870753_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114083673.1|857895_862821_-|DUF4011-domain-containing-protein	unknown	unknown	gnl|CDD|380141
NZ_CP046703.1|WP_114083674.1|856784_857708_-|polyphosphate-kinase-2	unknown	unknown	gnl|CDD|213852
NZ_CP046703.1|WP_147262540.1|854720_854831_-|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|350312

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP046703.1|WP_114083671.1|865344_866439_-|RNA-directed-DNA-polymerase	RT	pfam00078_RT_CAS-I:CAS-III	2.9e-33	110.0	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046703.1|WP_114083672.1|862892_864428_-|slipin-family-protein	gnl|CDD|259816	cd13438, SPFH_eoslipins_u2, Uncharacterized prokaryotic subgroup of the stomatin-like proteins (slipins) family; belonging to the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily. This model summarizes a subgroup of the stomatin-like protein family (SLPs or slipins) that is found in bacteria. The conserved domain common to the SPFH superfamily has also been referred to as the Band 7 domain. Individual proteins of the SPFH superfamily may cluster to form membrane microdomains which may in turn recruit multiprotein complexes. Bacterial SLPs remain uncharacterized.	4.84067e-103
NZ_CP046703.1|WP_114083664.1|875378_875843_-|SMI1/KNR4-family-protein	gnl|CDD|378155	pfam09346, SMI1_KNR4, SMI1 / KNR4 family (SUKH-1). Proteins in this family are involved in the regulation of 1,3-beta-glucan synthase activity and cell-wall formation. Genome contextual information showed that SMI1 are primary immunity proteins in bacterial toxin systems.	0.00205477
NZ_CP046703.1|WP_114083669.1|868176_868842_+|TraX-family-protein	gnl|CDD|368639	pfam05857, TraX, TraX protein. This family consists of several bacterial TraX proteins. TraX is responsible for the amino-terminal acetylation of F-pilin subunits.	4.46942e-32
NZ_CP046703.1|WP_114083671.1|865344_866439_-|RNA-directed-DNA-polymerase	gnl|CDD|239569	cd03487, RT_Bac_retron_II, RT_Bac_retron_II: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA branches out from a small ssRNA molecule via a 2'-5'phosphodiester linkage. Bacterial retron RTs produce cDNA corresponding to only a small portion of the retron genome.	2.32423e-90
NZ_CP046703.1|WP_114083663.1|876231_876516_-|DUF433-domain-containing-protein	gnl|CDD|225291	COG2442, COG2442, Uncharacterized conserved protein [Function unknown].	7.29549e-16
NZ_CP046703.1|WP_147262539.1|855812_855905_-|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|350312	cd18745, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily. The PIN_VapC4-5_FitB-like subfamily includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC4 and VapC5 ribonuclease toxins of the VapBC toxin/antitoxin (TA) system, and Neisseria gonorrhoeae FitB toxin of the FitAB TA system. This subfamily belongs to the VapC-like family of the PIN domain nuclease superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	4.0801e-06
NZ_CP046703.1|WP_114083729.1|872722_873370_+|methyltransferase-domain-containing-protein	gnl|CDD|225136	COG2226, UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism].	3.54551e-30
NZ_CP046703.1|WP_114083675.1|856217_856475_+|bacteriocin	gnl|CDD|275012	TIGR04149, predicted_protein, natural product precursor, GG-Bacteroidales family. Sequences in this protein domain family include a leader peptide region, up to and including a Gly-Gly cleavage motif, and about 15 additional residues, usually Cys-rich, from a family of predicted ribosomal natural product precursors. Many of these are associated with peptide-modifying radical SAM enzymes. The core region, up through the diglycine motif, resembles and contains some overlapping hits with the bacteriocin precuror leader peptide region modeled by TIGR01847, but is longer with an extreme N-terminal region with consensus sequence MKKLKKLKL. [Cellular processes, Biosynthesis of natural products].	0.00102012
NZ_CP046703.1|WP_114083666.1|873511_874309_-|dienelactone-hydrolase-family-protein	gnl|CDD|223489	COG0412, COG0412, Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism].	1.11776e-58
NZ_CP046703.1|WP_114083676.1|855294_855582_-|type-II-toxin-antitoxin-system-HigB-family-toxin	gnl|CDD|378301	pfam09907, HigB_toxin, HigB_toxin, RelE-like toxic component of a toxin-antitoxin system. HigB_toxin is a family of RelE-like prokaryotic proteins that function as mRNA interferases. HigB cleaves translated mRNA only, and cleavage depended on translation of the target RNAs. HigB belongs to the RelE super-family of RNases. The toxin-antitoxin gene-pair is induced by environmental stress factors.	4.05575e-34
NZ_CP046703.1|WP_114083673.1|857895_862821_-|DUF4011-domain-containing-protein	gnl|CDD|380141	pfam18741, MTES_1575, REase_MTES_1575. Vsr REase Fold. Fused to HEPN (SWT1/Abi2 family), along with Transglutaminase and wHTH.	3.063e-51
NZ_CP046703.1|WP_147262537.1|854922_855039_-|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|350312	cd18745, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily. The PIN_VapC4-5_FitB-like subfamily includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC4 and VapC5 ribonuclease toxins of the VapBC toxin/antitoxin (TA) system, and Neisseria gonorrhoeae FitB toxin of the FitAB TA system. This subfamily belongs to the VapC-like family of the PIN domain nuclease superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	1.44888e-08
NZ_CP046703.1|WP_114083665.1|874604_875144_+|DUF2267-domain-containing-protein	gnl|CDD|227789	COG5502, COG5502, Uncharacterized conserved protein [Function unknown].	1.64402e-26
NZ_CP046703.1|WP_114083668.1|869454_870411_+|Red-carotenoid-binding-protein	gnl|CDD|370323	pfam09150, Carot_N, Orange carotenoid protein, N-terminal. Members of this family adopt an alpha-helical structure consisting of two four-helix bundles. They are predominantly found in prokaryotic orange carotenoid protein, and carotenoid binding proteins.	1.62106e-90
NZ_CP046703.1|WP_114083674.1|856784_857708_-|polyphosphate-kinase-2	gnl|CDD|213852	TIGR03707, PPK2_P_aer, polyphosphate kinase 2, PA0141 family. Members of this protein family are designated polyphosphate kinase 2 (PPK2) after the characterized protein in Pseudomonas aeruginosa. This family comprises one of three well-separated clades in the larger family described by pfam03976. PA0141 from this family has been shown capable of operating in reverse, with GDP preferred (over ADP) as a substrate, producing GTP (or ATP) by transfer of a phosphate residue from polyphosphate. Most species with a member of this family also encode a polyphosphate kinase 1 (PPK1). [Central intermediary metabolism, Phosphorus compounds].	1.70334e-159
NZ_CP046703.1|WP_147262540.1|854720_854831_-|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|350312	cd18745, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily. The PIN_VapC4-5_FitB-like subfamily includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC4 and VapC5 ribonuclease toxins of the VapBC toxin/antitoxin (TA) system, and Neisseria gonorrhoeae FitB toxin of the FitAB TA system. This subfamily belongs to the VapC-like family of the PIN domain nuclease superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	9.94119e-09

Protein sequences

>NZ_CP046703.1|WP_114083671.1|865344_866439_-|RNA-directed-DNA-polymerase
MYSKNLTTTPLATESNLKKLQPDNLALLRWLRPPQASHSLAEYNTAEEIALAMGISLEKLHFLTTSTSQTRHYLPFKISKKTGGDRIISAPKPELKAAQRWILENILDKLEIHNAAHGFCKNRSIVTNAKPHVGANVIVNIDLKNFFQSISYNRVKELFSGFGYSESTATIFGLICTTAEIAINGQINYTASENRHLPQGSPASPAISNLVCRNLDSHLTAIAENLGFCYTRYADDLTFSASEDVSSKISNLIKNTKFIITSDGFTVNDDKTKISGKSVQQEVTGVIVNTQLNISKKTLKAFRATLYQIEQEGLSGKTWGKSTNLIAAITGFANYVAMINPNKGAEFKSSVERIKQKYGDSQTD
>NZ_CP046703.1|WP_114083672.1|862892_864428_-|slipin-family-protein
MQITMWQTFYIKPNEMGILYHRSDFKKILQPGTHTYFGRHWQVKIYDLNQPLAQIENLELLLRNHEAELQEHLLIIRTAFNQVALVRYGQNWVSVAPNKLIAFWRGFIEVESHLFNLEESLELPASFVQQLRSVALNGLKKLQISESEIGLLYLQNNFVRPLEPGEYAFWSVDRDVTVRILSRIIPNPDFPLEDVLIEKHPDFIAAYCETVQLQTSQVAIVRYRGKVISILPPTSRKLFWQGIAVEILDISADAQLQPNLVAELVEGSTEVKLLSRNCLHICQVPAQHVGLVYINQEFQGLRSPGVHAWWLFGRSFQTETIDLRLQNMEVSGQDILSKDKVPLRLNLTAGFRIQDPLRAKNGLSDISGFLYKELQFALRGAVGERNLDGLLEDKGAIDRSISEYIRQKAADYGIEVDSVGVKDIILPGEIKTILSKVVEAEKAAQANVVRRREETAATRSMLNTAKVMEDNPVALRLKELEVLERIAEKIDRIQVNGSLDSILTDLIRMNP
>NZ_CP046703.1|WP_114083673.1|857895_862821_-|DUF4011-domain-containing-protein
MRQSASDSQQNLTQKIEKWKAGLADLGRRNPLIKFRQDSPRTLEILTEEPDFIFTKLTEEKKSLRFLMIESEHQDINQEKKPKALSGEKNPLELITRQRGDEQLKRINKLRLEARRSFEERGVNSLFLAFGSLTWYDKDKPDDALLSPLILVPVELLKEPRRDVYKISLLDEDVVLNPTLTQKLKQTFGIELPEGEAVQGKTYSELITQIRQLLAQKTWQIKENVFLSLFSYAKAAMVRDIIENEALIFDHPILQAISGDLTTYQSNYREPLSASALDSQVKPERIFQILDADSSQQVVIEAAKAGSSFVVQGPPGTGKSQTIVNMIAELIGDGKSVLLVAEKETALSVVYKRMAECGLDHICLNLHHSGTTDKRELVNNLSKTIEYLKQIYGEENNHLFFERLVSSRQSLKLYLTSLHTKEKPLDKSPFEIFGELLKKEREAIPNINVIFSNFSQWNPSRLQEAKDLLNQLAQFLPFFKGEKTTIWAKSSLNSYSYEMELEITEKIEQFQQAIFLVQKINQELQETLQVQPLLNLESLDKCCPAIDYIRKAPLNLPENWTGVDIAIAQNAFTILQTDVQEIEKNKLSQEAENLLSRLSSYLPFLRGEKTTIWAQSTLNSCSETLELEIKNKINKLKQAISLIQTASQQLQMIMRIQPLLNLENVETCFPALKHMLKVPDKLPENWHELDISTAQDAFSKLKGDIKLLEETEPILKQKYNPELFSSELPALANRYQKYSRFWLIRIFNLQYRRDIKLLKKLSTKEGQISHNELKRDLTQAVQIQATRNKLYQSNYPARQIFGSLFNPEVSSEEELKAIEQSLSWLTDLQKYSLPAESAQQIVNSPSGRRELNQLVNKLESLPEDIKEGMDFLFSYFNENDIIGQYLPHNQISFIELATFLNLAQLDLPEFRQSLTYKEIFEQLESLGVQDFLDALRDNKPNPLESVQNKLRHINYQPRQVLGSLFNPEVCGEAELKEIEKALNWLIGLQKFSLSADSVQRILNSPSKRRRMAELVEEYESAHQSIRQGLDFLLSHFHESDITDYYLTRNQITFVELESFLSLAQSELSYFQEWLTYKETYQKLENLGNNKFLDTFRDNQIPTEQWFPVLEQRIYQICLDAILARKPELKNFNLEVHERQIKEFSKLDSTQLDTARKRLKQLHVQRWQNWEKTSLALAEIPNLKKEATKKSRHLPIRKLLNDTQKGIPNLVKALKPCWMMSPLSVSQYINPNVVHFDVLIFDEASQLRTEDVVPSIIRSNQVIVIGDNKQLPPTSFFSTGDSEEDIDDEDDESYESVLDECSKFMFAHLLKWHYRSQDERLIAFSNCHFYRNQLVTFPNPVQNPDLGVWFKHVPDGVYDRGKRRDNRREAEVVAQLALEHFQRFPEQSLGIIAFSEAQADAIREQIEILGKEYPDLETFCTDNSPQFFLKALENVQGDERDAIILSVGYARDDQGKLSLNFGPLNRQGGERRLNVAVTRAKSKITLVSSIVAGDIDKTRAQSKGVKLLHDYLEYAASGGERLQGNSYTDTLDFDSPFEEDVYHALVQQGYTIRTQVGCSGYRIDLGVVNGDRPGEFLLGIECDGASYHSSPTARDRDRLRQQVLERLGWKIHRIWSTDWFRNKPVQVHLLIEKIKQLQQINS
>NZ_CP046703.1|WP_114083674.1|856784_857708_-|polyphosphate-kinase-2
MSIDEVENQQNNGLVQPATDLIESLVKAKDKKKSKKSKRIFDGSTEVFAKKIPKKTFETELKQLQIELVKMQYWIKHTGYRVVVIFEGRDAAGKGGVIKRIADPLNPRGCRVVALGTPSDREKTQWYFQRYVQHLPTAGEIVLFDRSWYNRAGVERVMGFCTEAEYQEFMQSCPEFERMLVRSGIVLIKYWFSVSDDEQEERFISRSHDPARRWKLSPMDLESRDRWVEYSKAKDTMFAYTNIPEAPWFTIEADDKRRARLNCIHHLLSKVPYEDMTPPPLELPSRPVAEDYVRAPRNEQFFVPQVY
>NZ_CP046703.1|WP_114083675.1|856217_856475_+|bacteriocin
MAKIKNNAQLTFNEVELEELSDAEMKSVIGGASLASVPQFKVPQFQMPQFQLPQFEFQLPQFEFQLPEFQIPQIQLPEFQMPEFN
>NZ_CP046703.1|WP_147262539.1|855812_855905_-|type-II-toxin-antitoxin-system-VapC-family-toxin
MALSRKLVLLTRNHRDLGKVAGLLIEDWTV
>NZ_CP046703.1|WP_114083676.1|855294_855582_-|type-II-toxin-antitoxin-system-HigB-family-toxin
MHVITRKRLNEFAKLHPDTNNALTQWYQLVKGNEFVSFVELREMFPSADQVGKLTVFNIGGNKVRLIAAIHYNRQKVYIRAVLTHSEYDEGKWKE
>NZ_CP046703.1|WP_114083677.1|855061_855295_-|hypothetical-protein
MQSLNLDQTITAWSSIAENVFVPHTQEEYERLVEILDFLIDQVGEDETHPVASLMEVIGVLIENYETEHIPELEAIA
>NZ_CP046703.1|WP_147262537.1|854922_855039_-|type-II-toxin-antitoxin-system-VapC-family-toxin
MACCRTGAIALSRKLVLLTRNHRDLGKVPGLLIEDWMV
>NZ_CP046703.1|WP_147262540.1|854720_854831_-|type-II-toxin-antitoxin-system-VapC-family-toxin
MTGYSAIALSRKLVLLTRNHRDFSKIPKLLIEDWTV
>NZ_CP046703.1|WP_114083670.1|867431_868010_-|hypothetical-protein
MAKRKKSNLQWIKETLELKPDHRWESPSGYKIFVADRGAVRFNVPQDWILEPQDKSFKFLDKKPPNDDCCLEVSFNRLPPNDWSQFPLKSTLKKVLEDDSRNVIARGEIVTIKRQTARIVWTEMKFIDVQEEPREAFSRTCIGLGSNVQCLITFDYWADQAEQLIPVWDEAMRSLTLGLYIRDPMTGLAFPD
>NZ_CP046703.1|WP_114083669.1|868176_868842_+|TraX-family-protein
MIKVSAFSIKILAAVFMVMDHVCYLLMPEFRILHFIGRLSFPLFAWLLAKGEKHTQNVYRYGSRLLITAIISQPIYSVVFQSLSLNILYTLVLGLVMLRLVRHYSQLWQQLIITGLSAAVAESLGVEYGAYGIGVIFLMSLTDKLKPRVWLLCWCIFNFILVTLFIGNIFQHWAILAGFIVFQFNGKQGPRARWFYLFYPAHLIILGIINYLIHSRYSNPL
>NZ_CP046703.1|WP_114083668.1|869454_870411_+|Red-carotenoid-binding-protein
MNYTIESARNIFSSTQVADAVPATTAMFAELNIDDQLAFLWYAYAELGRTITPAAPGKANLQLMEGIFNEIKQMSHEEQTQLMRDLASNADTPISRSYAYFGVNAKLGFWWQLGEWMKQGIVAPMPVGYQMSTQVKAVLEAVQKIDQSQQITVLRNTVVNMGFDPSLADKKQAQINFNFPRASVSPQFTIEGVTEPTVLKYIEAMNADNFEAAVALFANNGALQPPFQKPIVGREAITSYLRDEGQGLVMKPTKGVSETIEDGYTQHKITGTVETPWFGGNVGMNIAWRFLLDPQGQIYFVAIDLLASPKELLNLTRK
>NZ_CP046703.1|WP_159402445.1|870579_870753_+|hypothetical-protein
MKRNPTLPPNFMLGYAIAAPNLQNYSSQGRRGLRTFQISSKRHDDHQIKFQSMLGFR
>NZ_CP046703.1|WP_114083667.1|871333_871756_+|hypothetical-protein
MARRKRTSAVLERAVRRAASINSIDPSLDLGNGLTLPAFSTLIEMMRTRENAYNSALSSLDKLYREMLETEDKLGDMTEHMLMAVGTRYGKSSVEYGMAGGVPKSQRRKGLRGESLTPSNEQPSFVASVESKNGKTAATS
>NZ_CP046703.1|WP_114083729.1|872722_873370_+|methyltransferase-domain-containing-protein
MQINQVIETYDRGAVDYDAIMKRYWHIEREPLIASLQLQPGQTVLDAAVGTGLNLSAYPEGVSVVGIDFSEKMMDEARKKRVSADITFKVSDLCNLDFPDNSFDAAASGFTLCVVEDPVLALKEILRVTKPGALIAILDYCKSQDPEIQKWQELIADGSSQLGFPTGKIKWDALMDYDELIYNSKLPIEVLVDDRIENPNPFLCGCQLLLKNLKG
>NZ_CP046703.1|WP_114083666.1|873511_874309_-|dienelactone-hydrolase-family-protein
MVETTNIEINTAKVKVPNNDLEIDAYLAQPAENGTFGAVIVFPEIFGINSNIRDITELIAKQGYVAIAPAMYQRIAPGFEADFSAEDVGFSPESYRLGLEYYQKVKYQDILSDIQATITYLKTLPNVKDDAIGVIGFCFGGHVAYIAATFPDIKATASFYGAGITTSSYGEETPTINRISEIQGTIYAFFGTRDTLISQAETEQIEAELKKHQINNRVFRYDAGHGFFAGFFKDKYPFMEQHPSYNPEAAPDAWQHVIELFQNHL
>NZ_CP046703.1|WP_114083665.1|874604_875144_+|DUF2267-domain-containing-protein
MPDQSFRTNIPEVDPTEIEDTRTAIADEHHSFLEKVMVKSGFADLYDARDFTEVVFRVMRDLMTTEASDRVESELHTEAVPTDEKALQFEVAELWKDTNPIVRFLSRIRQPLRGPAPIGIDSNLFLRRVANEGGIPGTVDAEQAVKAVFSATKDELSQERIQEIAGWLPDRIRELWEQA
>NZ_CP046703.1|WP_114083664.1|875378_875843_-|SMI1/KNR4-family-protein
MSALTEALEFVGDWVQQYMSNHPAAMNRGLSRDAIEAKAKELPFYLPEEIYELYQWKNGGVNPFLPHPDAWDLATFFSLEEAISIAQDWKGSFHLFSLFMVEDGGYFFVGTQEKCQTAPIYCNDIPEEVVEREPNYPSLTSMVQELVEELRSRS
>NZ_CP046703.1|WP_114083663.1|876231_876516_-|DUF433-domain-containing-protein
MSATDIGTLIVKSPETLGGRPRIAGTRVSVQRITAWYKLGLNAEEIAERMGNVNLTQVYAALTYYHANREEIEAYIFAERADYKRLATEMGQAI

Crispr_ID: NZ_CP046703_3

• CRISPR_ID: NZ_CP046703_3
• CRISPR_location: 1116686-1116783
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP046703_3

Consensus_repeat	Method
AGAGCTACGGTGTACACACAAGTC	CRISPRCasFinder

spacers of NZ_CP046703_3

>3.1|1116710|50|NZ_CP046703|CRISPRCasFinder
TGGAGTAGTTTACGAATCTGGTTTTTACCCCACCCTAATCCTCCCCTTGT

CRISPR arrays and Neighbor proteins around NZ_CP046703_3

CRISPR arrays

The CRISPR arrays of NZ_CP046703_3

>merge|NZ_CP046703|3|1116686-1116783|CRISPRCasFinder
AGAGCTACGGTGTACACACAAGTCTGGAGTAGTTTACGAATCTGGTTTTTACCCCACCCTAATCCTCCCCTTGTAAAGCTACGGTGTACACACAAGTC

>NZ_CP046703|3|3|1116686-1116783|CRISPRCasFinder
AGAGCTACGGTGTACACACAAGTC	TGGAGTAGTTTACGAATCTGGTTTTTACCCCACCCTAATCCTCCCCTTGT
AAAGCTACGGTGTACACACAAGTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046703.1|WP_114081094.1|1130535_1131699_+|1,4-beta-xylanase	unknown	unknown	gnl|CDD|226217
NZ_CP046703.1|WP_114080735.1|1124594_1125767_+|deoxyhypusine-synthase	unknown	unknown	gnl|CDD|179117
NZ_CP046703.1|WP_159402448.1|1108677_1109586_+|transposase	unknown	unknown	gnl|CDD|372577
NZ_CP046703.1|WP_114080966.1|1113008_1113446_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114081517.1|1116921_1118250_+|IS4-family-transposase	unknown	unknown	gnl|CDD|280446
NZ_CP046703.1|WP_159402449.1|1130101_1130314_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_159402443.1|1097756_1099070_-|hypothetical-protein	unknown	unknown	gnl|CDD|379252
NZ_CP046703.1|WP_114081129.1|1105381_1106749_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114081130.1|1107197_1107575_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114085619.1|1096489_1096840_-|four-helix-bundle-protein	unknown	unknown	gnl|CDD|183395
NZ_CP046703.1|WP_114081093.1|1131886_1132711_-|WecB/TagA/CpsF-family-glycosyltransferase	unknown	unknown	gnl|CDD|224833
NZ_CP046703.1|WP_114081131.1|1107578_1108700_-|CHAT-domain-containing-protein	unknown	unknown	gnl|CDD|378942
NZ_CP046703.1|WP_114080734.1|1119846_1123230_-|amino-acid-permease	unknown	unknown	gnl|CDD|236645
NZ_CP046703.1|WP_012408196.1|1123464_1124349_-|ParA-family-protein	unknown	unknown	gnl|CDD|224113
NZ_CP046703.1|WP_114080967.1|1113738_1116615_+|isoleucine--tRNA-ligase	unknown	unknown	gnl|CDD|235588
NZ_CP046703.1|WP_114080736.1|1125880_1128232_-|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|306677
NZ_CP046703.1|WP_114080964.1|1109740_1112053_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|276809
NZ_CP046703.1|WP_147262461.1|1112568_1112832_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114080733.1|1118617_1119772_+|histidine-decarboxylase	unknown	unknown	gnl|CDD|235068
NZ_CP046703.1|WP_159402428.1|1128390_1129863_-|IS66-family-transposase	unknown	unknown	gnl|CDD|376980

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046703.1|WP_114081094.1|1130535_1131699_+|1,4-beta-xylanase	gnl|CDD|226217	COG3693, XynA, Beta-1,4-xylanase [Carbohydrate transport and metabolism].	3.11745e-112
NZ_CP046703.1|WP_159402448.1|1108677_1109586_+|transposase	gnl|CDD|372577	pfam13359, DDE_Tnp_4, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	5.43172e-36
NZ_CP046703.1|WP_114081517.1|1116921_1118250_+|IS4-family-transposase	gnl|CDD|280446	pfam02281, Dimer_Tnp_Tn5, Transposase Tn5 dimerization domain. Transposons are mobile DNA sequences capable of replication and insertion into the chromosome. Typically transposons code for the transposase enzyme, which catalyzes insertion, found between terminal inverted repeats. Tn5 has a unique method of self- regulation in which a truncated version of the transposase enzyme acts as an inhibitor. The catalytic domain of the Tn5 transposon is found in pfam01609. This domain mediates dimerization in the known structure.	0.000409103
NZ_CP046703.1|WP_159402443.1|1097756_1099070_-|hypothetical-protein	gnl|CDD|379252	pfam13546, DDE_5, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	0.000188405
NZ_CP046703.1|WP_114080735.1|1124594_1125767_+|deoxyhypusine-synthase	gnl|CDD|179117	PRK00770, PRK00770, deoxyhypusine synthase.	0
NZ_CP046703.1|WP_114085619.1|1096489_1096840_-|four-helix-bundle-protein	gnl|CDD|183395	PRK12275, PRK12275, hypothetical protein; Reviewed.	2.87661e-53
NZ_CP046703.1|WP_114081093.1|1131886_1132711_-|WecB/TagA/CpsF-family-glycosyltransferase	gnl|CDD|224833	COG1922, WecG, Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane].	8.93887e-92
NZ_CP046703.1|WP_114081131.1|1107578_1108700_-|CHAT-domain-containing-protein	gnl|CDD|378942	pfam12770, CHAT, CHAT domain. These proteins appear to be related to peptidases in peptidase clan CD that includes the caspases. This domain has been termed the CHAT domain for Caspase HetF Associated with Tprs. This family has been identified as a sister group to the separins.	4.57613e-52
NZ_CP046703.1|WP_114080734.1|1119846_1123230_-|amino-acid-permease	gnl|CDD|236645	PRK10060, PRK10060, cyclic di-GMP phosphodiesterase.	2.0377e-121
NZ_CP046703.1|WP_012408196.1|1123464_1124349_-|ParA-family-protein	gnl|CDD|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	8.87109e-55
NZ_CP046703.1|WP_114080967.1|1113738_1116615_+|isoleucine--tRNA-ligase	gnl|CDD|235588	PRK05743, ileS, isoleucyl-tRNA synthetase; Reviewed.	0
NZ_CP046703.1|WP_114080736.1|1125880_1128232_-|PAS-domain-S-box-protein	gnl|CDD|306677	pfam00211, Guanylate_cyc, Adenylate and Guanylate cyclase catalytic domain.	1.36658e-70
NZ_CP046703.1|WP_114080964.1|1109740_1112053_-|tetratricopeptide-repeat-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	6.96653e-06
NZ_CP046703.1|WP_114080733.1|1118617_1119772_+|histidine-decarboxylase	gnl|CDD|235068	PRK02769, PRK02769, histidine decarboxylase; Provisional.	0
NZ_CP046703.1|WP_159402428.1|1128390_1129863_-|IS66-family-transposase	gnl|CDD|376980	pfam03050, DDE_Tnp_IS66, Transposase IS66 family. Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens.	6.54352e-41

Protein sequences

>NZ_CP046703.1|WP_114080967.1|1113738_1116615_+|isoleucine--tRNA-ligase
MTESGSYKDTVNLPKTSFDMRANAIKREPEIQKFWEENKIYDRLFENNPGELFILHDGPPYANGSLHIGHALNKILKDIINRYQMLRGRKVRYVPGWDCHGLPIELKVLQNMKSAERQNLTSLQLRQKAKEFALATVDNQRQNFKRYGIWGDWDNPYLTLKPEYEAAQIGVFGQMFLKGYIYRGLKPVHWSPSSKTALAEAELEYPEGHVSRSIYAAFAITSLSEAVKPLLAEYQSDLGVAVWTTTPWTIPGNLAVAVNADLNYAVVEVSHPEAQSNFKYLIVAADLVERLSSTLGVELTVKATFKGNDLEHTTYRHPLFDRESPIVVGGDYITTESGTGLVHTAPGHGQEDYIVGQRYGLPILAPVDDNGNFTEEAGQFAGLNVLGDGNQAVIDALAAAGSLLKEEPYPHKYPYDWRTKKPTIFRATEQWFASVEGFREEALKAIATVKWIPAQGENRITPMVAERSDWCISRQRAWGVPIPVFYDEATGEVLLNEEIINHAQAIIAEKGSDAWWELSVEELLPESYRNNGKSYRRGTDTMDVWFDSGSSWAAVVQQRPELRYPADIYLEGSDQHRGWFQSSLLTSVAVNDIAPYKTVLTHGFALDEQGRKMSKSEGNVVDPNTIIEGGKNQKVEPAYGADVLRLWVSSVDYSGDVRIGKNIIKQMNDVRGKIRNTARFLLGSLDDFDPEKDTVPFEELPELDRYMLHRITEVFEEVTEAFDSFQFFRFFQTVQNFCVVDLSNFYLDVAKDRLYISAKDAFRRRSCQTVLKIALDNLARAIAPVLCHTAEDIWQYLPYKTPYKSVFEAGWVQVEEKWRNPELAEFWETLRQLRTDVNKVLEQARIEKLIGSSLEAKALIHIPHKQLGDAIKAFNPVKGNGIDELRYLLLTSQVELLDSAEGLQGLKYTAQTEDWGIGVVNAEGQKCDRCWNYSTHVGESAEHPLICERCVAALAGKF
>NZ_CP046703.1|WP_114080966.1|1113008_1113446_+|hypothetical-protein
MSLRTRGSAAVDKAQLRLALLKSIDENLDLGHGLTIEAYNHLVNTTRATVEAHNTLVSNLEESRKTVTQMDKALSEMSERMLSGVATIYGRNSIEYSKAGGSNGKRNKKSSSKVAPLVAVLATQPAQAAIANASTNGKSTTPLLQ
>NZ_CP046703.1|WP_147262461.1|1112568_1112832_-|hypothetical-protein
MRTPNQQMRTPNQQMRTPNQQMRTPNQQMRTPNQQMRTPNQQMRTPNQQMRTLYQQMRTPYQQMRTLYQQMRTPNQQMRSPNRLFEK
>NZ_CP046703.1|WP_114080964.1|1109740_1112053_-|tetratricopeptide-repeat-protein
MNEQRLHAYNQLIQNLLDCPSGEEPEILAANTELLDADFVQVIVAAADHFAQQGEENTAEWLRNLATYLTTPETPLITQEEIETYGQFLQEILLAIADSNGDAQVIYPLLAANTDKLNDIFAELLRHWATNTLAEAEPDAATSIAAVIGNFSNLIQQFPLGSKASNMEIAIAGYEIALTVYTRSAFPEKWAMTQNNLGNAYGERIFGERADNIEFAIAAYNQALSVYTRSTFPVNWAGTQNNLGLAYGEKILGERAENIESAIAAYNQALSVYTRSAFPVDWAMTQNNLGIAYRNRIFGERAENIELAIAAYNQALSVCTRSAFPVDWAMTQNNLAIAYGERILGERAKNIELAIAAYNQALSVRTRSTFPVDWATTQNNLAVAYGERILGERAENIELAIAAYNQALSVRTRSAFPVNWAGTQNNLGNAYRNRILGGRADNIEMAIAAYNQALSVRTRSAFPVNWAMTQNNLGNAYRNRILGGRADNIEMAIAAYNQALFVYTRSTFPVDWATTQNNLGAAYGERILGERAENIELAIATYSAALSVYTRSAFPQNWATTQNNLGAAYSERIFGERAENIELAIAAYSAALEVRTRSAFPKNNATTLLNLGRLYQEEKLFDSAYNTFVSAIATVEGLRGDIISGEEAKRKQAEEWNKLYRRMVEVCLALARDTEAIEYIERSKTQNLVELLTKAASTSPENLTLVNHNIQFGEIQNLLDNETAIIQWYIFNDCFRAFIITSDNKPAIWHSSQQDLDALIDWSNRLIRES
>NZ_CP046703.1|WP_159402448.1|1108677_1109586_+|transposase
MTSPLARIESYPHEAKRLIGISYDHFLALVGLAEQRHIEKQAEIEKKKIRIIAPGGGRKPEMSAKEGICLCLVYLRQKPIFEILGLLFNISKTKANDAFNYWVDILRDILPASQIEEVSTDSQKYQELQRMLSEYELIVDSTEQPTARPVDYQEQKRYYSGKKKMHTLKNQFIVLPGGEDIVDVRVGMLGKTSDINLFRETRHKFTDTQQFLGDKAYIGDDAITTPHKKRKNTEISELQKQENKELSSRRIAVEHMICRVKIFRVASDRFRLARHRYNQVILAVCGLVRLRINRLFSVTLST
>NZ_CP046703.1|WP_114081131.1|1107578_1108700_-|CHAT-domain-containing-protein
MLAKGLVIFFPHNCYSNFLLSHAIYIKDKSNEYLNDYYNPEDQDKIQWQNQLEERLKKLAEILHIEKILDLVSKQCDRLILIPHRYLHLFPLHALPVKKSYLIDLFPNGVGYAPSCQLLQQIQLRQRPDFQSLFAIQNPTEDLYQGYEKDLGAVGTIKKQFADTHILKQDQANKSAILLGINENIHNVTLNEKLLKANCAFFFCHGYFNSASPQDSGLQLADGNLTLADIITHFKLENCRLVTLSACETGLTDFTSTSDEYIGLPSGFLLAGSTNVVSSLWTVDAIATALLMIKFYKELQQQNNIVLALNTAQRWLRDSTVQGFQDWLINSSLSWGCKKYLNKYFAANHENALTKPFESPFYWAAFCNIGKGV
>NZ_CP046703.1|WP_114081130.1|1107197_1107575_-|hypothetical-protein
MSIYRNSIEAFIQVLNSQSNLIPTQDWNELQQLSSQLPEDNEEIVEILENWLQSESRNQVLEAYKQNLESITDKLPINVSTNIGIANSKSQTPVNQPSESSKELVDNAIKNNSPLSDDKKPQPKP
>NZ_CP046703.1|WP_114081129.1|1105381_1106749_-|hypothetical-protein
MKNFSLSLYAFHLRHTLTELPGEVVTDANLLWENLVKVGESLLTFVGLKDLRSKLICYQNGKYEPKREIGRIPERLIDAQDLDLGSLLTTEGFKINANLQPFLLNDTYAVDLTLVPEPPNISIDIPQLQHFKPSSLLPSNIQASLGQTLSIYGEVDPTEDCDTLAEKLAIALVAGTNLNPVRIQQGELFGSLLFEYQALDPDEPDNPAKQCHILIVINNNQAATATLAAEAYDWLLNLLCSYHKILYIYQLARQRYREARTIYSDLENKIQKFNSLISENQTQLSGLKSLMGEIPKKIFDYTRCLQDLQIHHTTITTNITNYTTCLEKIQTIDSGNSPQSWQDFINKDCKKWQQQIQTDINYLTPGQELFGQLVDTIRGIVETEQTERDRSLENTIQILGIGFGGGAIASGVFTTHIDKINVPLVQKHPLYASLTLSIIATVVFIALGWLITKRK
>NZ_CP046703.1|WP_159402443.1|1097756_1099070_-|hypothetical-protein
MILTQLEKFRQGIYDCLGKAKDAVFELMDAVLTSPSIPSFVSLSQSPVFRRQWSSIYAALHDSRPPKRKLMKLLVQEVVTDEQPFLAGDHSFWARPEAKTLKERTFHGDSRGSIGIGQSYSTLAWIPEADGSWALPLKHERITSFETPTSKAAFQLKQITRELGKRPLAAYDRGYGNAKFVQATEKIDADLLLRLASNRCVWGTPGTYKGRGAPCKHGHKFKFNDSETWAEVTETLEVEDPQVGRVKVMRWSGFHFLQSPNRAMEIIRVEVIQPVGRNRKFQPLWLAWLGQTMPPLEDLWQKYLRRFALEHWYRFAKQRLYWTQPQLGSTQAAERWSDLMPLLTWQLWLARLACIDSPLPWQSTQDKLSPGRVAQAFPLILATIGTPAQPPKTRGKSPGRAQGHQPPSRKRYPTVKKHASKKPKTEESLKNADLTAA
>NZ_CP046703.1|WP_114085619.1|1096489_1096840_-|four-helix-bundle-protein
MSYRNQFIWQRAVQLAINCYKFTRLFPQSELYGLTSQIRRSSVSVASNIAEGYGRRSKPEYIQFLHIALGSLRELDTQLIIAKEVDLAEKNLFTPLLNEVEEMQSILVASLNKLKA
>NZ_CP046703.1|WP_114081517.1|1116921_1118250_+|IS4-family-transposase
MGKHQSVSIRQISKNRAEQIGYYRFLENKSVTVGELVRSLSDHCVSHVEGKHILAISDTSEINLQSHVGRLEALGLGVVGNNRDIGFYIHPTLVLDAANGFPLGISTVKLWTRDINHQDKHERNYSQLPIEEKESYKWLRSADETQQCINVGEAKMITHIGDRESDMYEEFVTVANQDNHVLVRARIDRRLVGKTSSFYTYLNQQPSEGTYTVDVPADARTSRTAREALLIVRRAMVKIQRPDKLNGQDYPPSVTLYAVEAVEVNPPPGQAPIHWRLLTTHQVVCLEQALQVIRWYTWRWRIEQLFATLKTAGLNLEATQLESIAAIQRLTVLALSVAVRILQLIQGRDNPNLPATVAFSHEQQHCLSSISPTLEGKTQLQQNPYLPSSLPWATWIIARLGGWSGYKSQKPPGITTLVRGLEQFESTFFGWKLALGKLVCTP
>NZ_CP046703.1|WP_114080733.1|1118617_1119772_+|histidine-decarboxylase
MSSKVAKELADFLLQIEQRSQFHAGYPYNLSCDYSAIGKFFNHLLNNAGDPYIEPDFGLHSRKFEQEVLAFFAHLYKIPENQFWGYVTAGGTEGNLYGMFLAREIYPNGILYSSQDSHYSIPKAAKLFRIQHNVVNSQINGEMNYDHFEQQLSENRRYPAIINLNIGTTVKGAIDNLDKVLEILERNQIKDYYIHCDAALSGLILPFLDGAPQVNFQKPIDSVAISAKFIGSPLPCGVVLTKKKWVEKVETEIEYIGSKDTTILGSRNGHTPLILWYAVQTRGYDGLAKEAKTCIHNAQYLFQQLQIREYPCMLNNFSNTVVFQKPSQRLIKKWQLAVFENSAHMIVMQNIGREKIDIFINELLLEEGLVNNAEDFQLQPVLQH
>NZ_CP046703.1|WP_114080734.1|1119846_1123230_-|amino-acid-permease
MLTQNSIPTEKNQNLVIRLPRTLSYLETWGFGLTGHVGWIGTAPIIHAALGPKAILVWFVGTIISFLLNLQVQSLGRRWPDVAGGTPNYITRLLKNFPGLGRYVALGYFFSWAAAPALYAIILTDLIKVNFETLGIYCPETLLKVLFTAIPFILAFSGTRALALLHLFFVFPAILLLLLFSVEGVLWLAFSNANLKFIPTSTHTISFEEWAKWFFLASYSIYACETTSSFVADSHHPYKTLSFLTVAAWLIPPVFLGGSWVLMCSGQNPTIGNDAFLNLVAASKPFWGESASFLATLLITVSCLLSSATAVSNSPRILYQLALDRQISPIFALVSRQGVLGPAIFLTFLISLLCLNLGNVSQLVTVAGTCYLMSIMGLHLGLWLCRGKPQVLWPWWSLGFFFLEAVVLIVGGLAWNWRDFSVGLLLPIVLMIGDVGLRRLRFAPLQLEWWTQRYYTRSSTNNSDFLILQVIVLVSLICITATSSWVIRDLLGKVSDNPQNSLLAILLVTLSLIGVAIACWTTLPQIVAIDEARKQAKSLFITTLDTVPDTVLVLDENGKICQTNAAAEELFQTHSQELLGQNLNQLLVCYHGKPKQWSIRTEQTLKINQGLRIVESTISQPFNSQLREYVVIIRDITKRKLVEEELIQYRYQLEQLVLERTVELIRVNQQLEQDIIKRQQAQEQLLHNSLHDGLTGLPNQRLFMERVQQAIERTKQHNNYLFAVLFLDLDRFKVVNDSLGHLLGNQLLIAISHRLKSVLRGGDIVARFGGDEFTILIEDIEDIDIAIQVAERIKKVLALPFQLNEHLVFTNASIGIALSKPDYEQSAHILRDADVAMYRAKSLGKARYEVFDQKMYEGASLLLELETALRNALLKQEEFRLDYQPIISLITGKIIGFEALIRWHHPERGLISPQEFIPLAEETGMIVSIGQWVLSEACQQMHRWHQQFPSSLPLTISVNFSGKQITQPDVFKQVKHILQETGLEPCSLKLEITETLLMDNFELATTVLSQLTELNVEMHMDDFGTGYSSLSYLHRLPIKTLKIDRSFVTNIGSRGENLEIVRAIVTLAHNLNMSVTAEGIETVEQLAQLKALQCDYGQGYFFLPPMESAEVEMLLAANLCYKNFLKR
>NZ_CP046703.1|WP_012408196.1|1123464_1124349_-|ParA-family-protein
MGYVIATANMKGGVGKTTLTVNLATCLAKNHGKRVLVLDLDSQISATLSLMSPLDFAKRRKQSKTFRYLIDEVINPDPQAKLTIQDIIQSQVCNLPGLDLLPGDIDLYDEFVVSEMLHQQATALGEQDFETIWNRFERVLINNILKPVRQEYDFILLDCAPGYNLLTRSALAASDFYILPAKPEPLSVVGIQLLERRIAQLKDSHGHETKIDIKMLGIVFSMSTANLLTGRYYKQVMHRVVEDFGVEKICKVQIPVDVNVAKAVDSFMPAVLNAPQSAGSKAFFQLTQELLQKL
>NZ_CP046703.1|WP_114080735.1|1124594_1125767_+|deoxyhypusine-synthase
MSKQLGQKIAPTPISNDINVVDLIDQYFTAYNSARLREICQLLSRDVLTEGVTVGVSLSGAMTPAGFGVSALAPLIRNGFIDWMISTGANLYHDMHYGLGFELFAGNPFLDDVKLRQEGTIRIYDIIFGYDVLLETDAFIRKILQGEAFQKRMGTAEFHHLLGKYVREVEKQLGVQHSCLLATAYEYGVPIYTSSPGDSSIGMNVAALALEGSQLVLDPSIDVNETAAIAYNARESGGKSAAVILGGGSPKNFLLQTQPQLHEVLGLEERGHDYFVQFTDARPDTGGLSGATPSEAVSWGKIDPEELPNTIVCYTDSTIALPLVTAYVLNKCQPRPLKRIYDKREAILDKLQKDYLAAKSQPSDQVPAAVAESAQKQTATYPCGRLIPNT
>NZ_CP046703.1|WP_114080736.1|1125880_1128232_-|PAS-domain-S-box-protein
MKDQLLDRIFNKPSLPDKFEHLELDDHFCIINKSEQVQRFADSPEEVIQGKDIRLSFPEFIGLEKILQAILRGEQQLFDLEAIGRRSNQKYIYMNIYIIGNHNENKFRNKLIVFIEDVTNKFILKQNLAQQTYEEKLRKDALTAYNTYMEKIINSMPDALLITSSKGNIKRVNNAAQELFGFSEEELINRPLSLIMDDDHFLIESIFKNYYFRQNFQNLEVVCRTKTREKWLIAFSCSVIPKKIQGLEDIVYIGRDITARQYREQRTSTQYAITRILSESQSVKQAIPQILQSICQNLGWHLGELWAPSQYIGTSVQGHSINAILRCVEIWSSRVISVREFKAITWQTTYTPGIGLPGRIWIRRLPLWIKDITEDGDTRRSQPAAEAGLHAAFGFPILDDSEILGVMVFFSRDVQPKDKDLLKMMGSIGSQIAQFIKRKQAEDALIESEERYRDLFENANDLIQSVNVYGRFLYVNLAWQETLGYSEAEIANMTIFDIIHPEFKQECWQRFYRVLSGEKFDQVKAAFVTKDGQTIFLEGNINCKFSEGHPVAVRGIFRNVTQRIAAEEALRYQQEETERLLLNILPTAISKELKEESANIAEEFADITVLFADIVGFTEIAASMSAIQVVNLLNSIFSTFDRLTEQYGLERIKNISDAYMVVGGLPTHRPDHAQAIALMALHIQTAIALFNTENNQNFNIRIGIHSGSVVAGVIDLNKFTCNLWENTVNIASCMESQGIAGKIQVTEDTYKSLCNEFLFQKRGEIEVKGKGKMTTYFLVGQKG
>NZ_CP046703.1|WP_159402428.1|1128390_1129863_-|IS66-family-transposase
MEKNLPLKLDTETLKQLEKEQLVEMLMEQAKAIEQLKSRVIELESVIEKLKVSRDLDSTTSSKPPSADILKKTEKKLEDEAGESETPKRKPGGQPGHRGKTRKGFGRVDRFEILRPQVCFCCGQKEFSNEPIKIETQQVAQLVERPIEIVEYQRHTCICSECGSKQTADWSPEIVPGQDIGIRLQAFLGWINNYGHLPYEKQQELLWELGEIEIGVGTLVATNERIDGAVAQSIDNLKEWIKQTQPNIHSDETPWVIKGVKEWLWIFANTDFALFHAADTRSRAELEAILGSSYSGVLSSDDFSAYNGYPVKAQQKCQAHLRRHFKKLILIPGLNNKEIGSAFVSLIDEGFKNYALFQQTKNIDEFWSWASEFKIKVESSIHSWIDKAGGEAGKLLRSLRNKAHQWWYFLDHPDIPPDNNLAERTLRLAVTKRKVSGGSRSMKRFQDTANLLTVIQTCRRQGRSVIEFFDQAIKAMVNSSVQTPSLIPLV
>NZ_CP046703.1|WP_159402449.1|1130101_1130314_-|hypothetical-protein
MNLSILRVVLLNWRSLINYVLEYKLLKTKLYSIVNPPKDITYIIDAYLILINQIKSLLVAVFAQLQLVKS
>NZ_CP046703.1|WP_114081094.1|1130535_1131699_+|1,4-beta-xylanase
MPYRRKFLKRAGYTTLSALLTMGFLQKDRQKEDGTTNAATANYLSASANVNSPLRQLAAAKGKRYGAAVSSEFLLQEKGYADLIARECSIVTPNGELKWNATEPQPGKFTFESADAIAGFCQKHNIQLHGHTLFWHMGKPDWLPYPPTLKMLERHVKGVMGHYRNSPVLKSWDIANEIIADSENETDNPTYGLRKGVKRELIRDLFLIAASVDSSKKFYLNDFGIEGATWKSDRFLKMVEYLKNSGVKIDGAGIQSHLWFSTAYGFDQKGFNSVLKRLNNLQVKPIITELDIIIDAPLPDSIKKLDQMVADSYKRYLDLCFAGGVDTVITWGITDRHTWIRHPDWMPGKTFRNNPSIWKFLRPLPFDENLQPKLARNAIAQAFQQAT
>NZ_CP046703.1|WP_114081093.1|1131886_1132711_-|WecB/TagA/CpsF-family-glycosyltransferase
MKNRFSYKLLGVKVDALSIPELNLLIEESIEKSEKWIIANHNLHSLYLFHNDPKMQAFYAKAEYIHIDGMPLLFIGKLLGFPMKREQRVTYADWVWPLMAEAANKDWRVFYLGSKPGVAEQGASILREKFPGLQIACAHGYIDMDKDSEENLATLAAINAYKPHVLMVGMGMPRQEHWISENLEYIYANTILTSGACMDYVAGVVPTPPRWMGRVGLEWLYRLLSEPKRLWRRYLLEPWFVATLFLREIWSMPSQQKKNRMLLFLTTRFHKFVA

Crispr_ID: NZ_CP046703_4

• CRISPR_ID: NZ_CP046703_4
• CRISPR_location: 1715210-1715307
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP046703_4

Consensus_repeat	Method
GACTTGTGTGTACACCGTAGCTTT	CRISPRCasFinder

spacers of NZ_CP046703_4

>4.1|1715234|50|NZ_CP046703|CRISPRCasFinder
ACAAGGGGAGGATTAGGGTGGGGTAAAAACCAGATTCGTAAACTACTCCA

CRISPR arrays and Neighbor proteins around NZ_CP046703_4

CRISPR arrays

The CRISPR arrays of NZ_CP046703_4

>merge|NZ_CP046703|4|1715210-1715307|CRISPRCasFinder
GACTTGTGTGTACACCGTAGCTTTACAAGGGGAGGATTAGGGTGGGGTAAAAACCAGATTCGTAAACTACTCCAGACTTGTGTGTACACCGTAGCTTT

>NZ_CP046703|4|4|1715210-1715307|CRISPRCasFinder
GACTTGTGTGTACACCGTAGCTTT	ACAAGGGGAGGATTAGGGTGGGGTAAAAACCAGATTCGTAAACTACTCCA
GACTTGTGTGTACACCGTAGCTTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046703.1|WP_114083317.1|1700200_1701517_-|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl|CDD|273776
NZ_CP046703.1|WP_114083983.1|1724094_1725657_-|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|224154
NZ_CP046703.1|WP_114083318.1|1698896_1700102_-|FtsX-like-permease-family-protein	unknown	unknown	gnl|CDD|182528
NZ_CP046703.1|WP_114083314.1|1706996_1708562_-|glucosaminidase-domain-containing-protein	unknown	unknown	gnl|CDD|376625
NZ_CP046703.1|WP_114083359.1|1703502_1705425_+|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	unknown	unknown	gnl|CDD|235362
NZ_CP046703.1|WP_114083315.1|1705655_1706969_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114083979.1|1719759_1721064_+|O-acetylhomoserine-aminocarboxypropyltransferase/cysteine-synthase	unknown	unknown	gnl|CDD|273555
NZ_CP046703.1|WP_114083982.1|1722597_1723929_-|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|225459
NZ_CP046703.1|WP_114083316.1|1702251_1703124_-|peptidase-M15	unknown	unknown	gnl|CDD|367124
NZ_CP046703.1|WP_114083312.1|1709945_1710893_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|236011
NZ_CP046703.1|WP_114083976.1|1716448_1717396_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|276809
NZ_CP046703.1|WP_114083977.1|1717645_1718038_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_159402616.1|1713742_1715071_-|IS4-family-transposase	unknown	unknown	gnl|CDD|280446
NZ_CP046703.1|WP_114083311.1|1711885_1713451_+|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|224154
NZ_CP046703.1|WP_114083313.1|1708651_1709413_-|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl|CDD|119407
NZ_CP046703.1|WP_114083975.1|1715724_1716330_+|DUF411-domain-containing-protein	unknown	unknown	gnl|CDD|225564
NZ_CP046703.1|WP_159402467.1|1721156_1721300_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114083978.1|1718663_1719575_+|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl|CDD|238882
NZ_CP046703.1|WP_159402466.1|1715409_1715571_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114083981.1|1721371_1722442_+|homoserine-O-acetyltransferase	unknown	unknown	gnl|CDD|273596

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046703.1|WP_114083317.1|1700200_1701517_-|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl|CDD|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	1.65355e-50
NZ_CP046703.1|WP_114083983.1|1724094_1725657_-|NAD(P)/FAD-dependent-oxidoreductase	gnl|CDD|224154	COG1233, COG1233, Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	1.22557e-34
NZ_CP046703.1|WP_114083318.1|1698896_1700102_-|FtsX-like-permease-family-protein	gnl|CDD|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	5.35308e-73
NZ_CP046703.1|WP_114083314.1|1706996_1708562_-|glucosaminidase-domain-containing-protein	gnl|CDD|376625	pfam01832, Glucosaminidase, Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase. This family includes Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase EC:3.2.1.96. As well as the flageller protein J that has been shown to hydrolyze peptidoglycan.	1.44392e-09
NZ_CP046703.1|WP_114083359.1|1703502_1705425_+|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	gnl|CDD|235362	PRK05192, PRK05192, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG.	0
NZ_CP046703.1|WP_114083979.1|1719759_1721064_+|O-acetylhomoserine-aminocarboxypropyltransferase/cysteine-synthase	gnl|CDD|273555	TIGR01326, Includes:_O-acetylhomoserine_sulfhydrylase, OAH/OAS sulfhydrylase. This model describes a distinct clade of the Cys/Met metabolism pyridoxal phosphate-dependent enzyme superfamily. Members include examples of OAH/OAS sulfhydrylase, an enzyme with activity both as O-acetylhomoserine (OAH) sulfhydrylase (EC 2.5.1.49) and O-acetylserine (OAS) sulphydrylase (EC 2.5.1.47). An alternate name for OAH sulfhydrylase is homocysteine synthase. This model is designated subfamily because it may or may not have both activities. [Amino acid biosynthesis, Aspartate family, Amino acid biosynthesis, Serine family].	0
NZ_CP046703.1|WP_114083982.1|1722597_1723929_-|FAD-dependent-oxidoreductase	gnl|CDD|225459	COG2907, COG2907, Predicted NAD/FAD-binding protein [General function prediction only].	7.93919e-47
NZ_CP046703.1|WP_114083316.1|1702251_1703124_-|peptidase-M15	gnl|CDD|367124	pfam02557, VanY, D-alanyl-D-alanine carboxypeptidase.	8.49212e-12
NZ_CP046703.1|WP_114083312.1|1709945_1710893_-|AAA-family-ATPase	gnl|CDD|236011	PRK07399, PRK07399, DNA polymerase III subunit delta'; Validated.	9.48198e-173
NZ_CP046703.1|WP_114083976.1|1716448_1717396_-|tetratricopeptide-repeat-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	4.08223e-14
NZ_CP046703.1|WP_114083981.1|1721371_1722442_+|homoserine-O-acetyltransferase	gnl|CDD|273596	TIGR01392, Homoserine_O-acetyltransferase, homoserine O-acetyltransferase. This family describes homoserine-O-acetyltransferase, an enzyme of methionine biosynthesis. This model has been rebuilt to identify sequences more broadly, including a number of sequences suggested to be homoserine O-acetyltransferase based on proximity to other Met biosynthesis genes. [Amino acid biosynthesis, Aspartate family].	2.34413e-166
NZ_CP046703.1|WP_159402616.1|1713742_1715071_-|IS4-family-transposase	gnl|CDD|280446	pfam02281, Dimer_Tnp_Tn5, Transposase Tn5 dimerization domain. Transposons are mobile DNA sequences capable of replication and insertion into the chromosome. Typically transposons code for the transposase enzyme, which catalyzes insertion, found between terminal inverted repeats. Tn5 has a unique method of self- regulation in which a truncated version of the transposase enzyme acts as an inhibitor. The catalytic domain of the Tn5 transposon is found in pfam01609. This domain mediates dimerization in the known structure.	0.000425976
NZ_CP046703.1|WP_114083311.1|1711885_1713451_+|NAD(P)/FAD-dependent-oxidoreductase	gnl|CDD|224154	COG1233, COG1233, Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	1.8724e-91
NZ_CP046703.1|WP_114083313.1|1708651_1709413_-|N-acetylmuramoyl-L-alanine-amidase	gnl|CDD|119407	cd02696, MurNAc-LAA, N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino acids in certain cell wall glycopeptides. These proteins are Zn-dependent peptidases with highly conserved residues involved in cation co-ordination. MurNAc-LAA in this family is one of several peptidoglycan hydrolases (PGHs) found in bacterial and bacteriophage or prophage genomes that are involved in the degradation of the peptidoglycan. In Escherichia coli, there are five MurNAc-LAAs present: AmiA, AmiB, AmiC and AmiD that are periplasmic, and AmpD that is cytoplasmic. Three of these (AmiA, AmiB and AmiC) belong to this family, the other two (AmiD and AmpD) do not. E. coli AmiA, AmiB and AmiC play an important role in cleaving the septum to release daughter cells after cell division. In general, bacterial MurNAc-LAAs are members of the bacterial autolytic system and carry a signal peptide in their N-termini that allows their transport across the cytoplasmic membrane. However, the bacteriophage MurNAc-LAAs are endolysins since these phage-encoded enzymes break down bacterial peptidoglycan at the terminal stage of the phage reproduction cycle. As opposed to autolysins, almost all endolysins have no signal peptides and their translocation through the cytoplasmic membrane is thought to proceed with the help of phage-encoded holin proteins. The amidase catalytic module is fused to another functional module (cell wall binding module or CWBM) either at the N- or C-terminus, which is responsible for high affinity binding of the protein to the cell wall.	5.03278e-45
NZ_CP046703.1|WP_114083975.1|1715724_1716330_+|DUF411-domain-containing-protein	gnl|CDD|225564	COG3019, COG3019, Predicted metal-binding protein [General function prediction only].	5.43676e-54
NZ_CP046703.1|WP_114083978.1|1718663_1719575_+|SGNH/GDSL-hydrolase-family-protein	gnl|CDD|238882	cd01846, fatty_acyltransferase_like, Fatty acyltransferase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases. Might catalyze fatty acid transfer between phosphatidylcholine and sterols.	4.53098e-89

Protein sequences

>NZ_CP046703.1|WP_159402616.1|1713742_1715071_-|IS4-family-transposase
MGKHQSVSIRQISKNRAEQIGYYRFLENKSVTVGELVRSLSDHCVSHVEGKHILAISDTSEINLQSHVGRLEALGLGVVGNNRDIGFYIHPTLVLDAANGFPLGISTVKLWTRDINHQDKHERNYSQLPIEEKESYKWLRSAYETQQCINVGEAKMITHIGDRESDMYEEFVTVANQDNHVLVRARIDRRLVGKTSSFYTYLNQQPSEGTYTVDVPADARTSRTAREALLIVRRAMVKIQRPDKLNGQDYPPSVTLYAVEAVEVNPPPGQAPIHWRLLTTHQVVCLEQALQVIRWYTWRWRIEQLFATLKTAGLNLEATQLESIAAIQRLTVLALSVAVRILQLIQGRDNPNLPATVAFSHEQQHCLSSISPTLEGKTQLQQNPYLPSSLPWATWIIARLGGWSGYKSQKPPGITTLVRGLEQFESTFFGWKLALGKLVCTP
>NZ_CP046703.1|WP_114083311.1|1711885_1713451_+|NAD(P)/FAD-dependent-oxidoreductase
MEIFDYVILGAGLGGLSAAACLTRQGYRVVVLEQHYLPGGCCHTFDYGEYRFCADVHYISQCGSGQTVGQFLDYIHQNVPFNSLDSDCIDRVITPEADFKIPLGWENLRSRLLSTFPEEAGAINHYCNEIQQLHQEIRNLVQEVRWYDQKLSDWLKLPKYLNLFWKRNWTLQDLYNHVGLSPKLQAVLAGQSGDYALPPQEIALLTHTSLVWDYSEGAYYPKHHFKHLVDTIAQVITAGGGVIKYSTPVSHIQVSNHSVLSVLADGNSYHASKAYISDLDPKLTVELMHDITALSQKEHQRLTSYQYSASAFNIYLGLDSRFDPQRYGIGNWNVWYYPTGDLNREYQQQLEGDFSQPWIFLSCPTMKSSEPGMGPEGHHVLEIATVCSYEPFEHLYKSNPKAYKAKKREFYQQIMTSVRDFIPDVDKYARMKVYGTPTTSEFYLGQPQGNIYGAKLVPKQVGLNRLGYTTELPNLFLVGASAGYPSVPGVIGNGMDVVELLTGQSVWHKAAERPQPLVAIG
>NZ_CP046703.1|WP_114083312.1|1709945_1710893_-|AAA-family-ATPase
MTIDPFATLVGQQQAIELLTQAVRQNRVAPAYLFVGPDGVGRSLAARCFIELLFSSEMGVTAALQNRLRQGNHPALLWVQPTYQYQGQRLTAAEAVEKGLKRKAPPVIRLEQIREITEFLSRPPLEAPRNVVVLEEAQTMAEAAANALLKTLEEPGQATLILIAPTPESVLPTLVSRCQRIPFYRLDAQSLAVVLTQTSHQEILQNQAVLSIAAGSAGSAIASYEQLQTIPPELLEDLKKAPASYRKALELAKKIDKDLDTEAQLWLVDYLQQLYWQRWHQPSIINQLEQSRKYLLAYAQPRLVWECLLLSICQK
>NZ_CP046703.1|WP_114083313.1|1708651_1709413_-|N-acetylmuramoyl-L-alanine-amidase
MKFGIDMGHNCPPDTGATGIKQEDALTKAVGTQLIQKLRAANHTAIDCTPTSASSVTDSLRQRTNKANANNVNVYVSIHFNKFNAKAHGTEIYAISNASQGIAESVLKEIVQLGFYNRGVKDTGFFVLKNTQMPAILIECCFCDAQVDMDLFDVEKMAEAIKDGLIGQPKPKEPKADKKYVLEITTKTFLKPSTEQASDLPKDSIFEIEPGDYPILDVIFEENHYSVKWPDQSKGNRNEHFVYAGHAKVIEKD
>NZ_CP046703.1|WP_114083314.1|1706996_1708562_-|glucosaminidase-domain-containing-protein
MPLLDDLVNNYSNKDLVKIFTQVGIESAKITDINRQILKEVTLAQWLLESSRGKSDLAVNANNFAGLKWRIPDMKGFAEPLKIKVPSEPEEVEFCKFTDIDAFIIGYWKFLTRTPYKGLEEYTNTPENFLGFLKAKGYSSDPKYVSKVVDLLPEAQKLLANAGGVTIPASVEQLQLIRVPKEVELWQNFRVEGVAPLTASGKFLSITSDDKFTVVSVAISQDGKWQFDFVFKQAGDRRMIITVDDQTLEIPIKVVVPFDHKDDENTQQPTASSLPGAKVIKLEGSVGIGGVNKAADVKAIKARLYELGYKWVGDPDSADRDRGLFDAIKLFQSIIAGRSTVNGDGRVDVGGITHRWLQAANAPRWELMPKSDPNNGLVNGELEDTQDNHDFGTHWLADVIKKIAQDYQNSYRNTHPLAAPFAINDVSLPHGGDTPDHHGHETGMMCDIYLPQKNGNFGGIVWSSSNYDRDAARAILKSITNQKLVRAVFFNDQQLIKEGLCVSLNGHDNHIHFEINPPVRS
>NZ_CP046703.1|WP_114083315.1|1705655_1706969_+|hypothetical-protein
MLQEASTRLIVPEPSEDLIANEPWSIENYADGLMDELFADIDYILDVSDHLPSQTVRHGRQNKAQRHSPPEYVPLQTVTIPQIILPNGQSVTQNNNKHLSTVVFDNATIKPVSRKRQKSSRTLGKLLIVGTTLGVAIAGILYLVQSGVVYLLNPNLTQQALLAPQTQSQLPGKTEIEADLVDYMLGALAVIDKQELKGNRKSFSSGFSSQTNTNQIALGNGQINGNLPPLPLLANNTPPAPNRSGSVVERIYVPVYQAPSPMRYALPAIPGSPALLPQVANALQASQPNVVKSALNTVRQATKPVTVNMLAAAVRAELKPVAGRTVPITVRQTPKPLPALPVVPLRAALAPESEPTITQEQVYPATAIAVAPSNTLEGLLELGNKSAALFKIDGVTRRINMGESIGQSGWTLVEVSNGEAVIRRNGEVRSIYTGQKL
>NZ_CP046703.1|WP_114083359.1|1703502_1705425_+|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG
MTMHNSVQFQDAFDVIVVGAGHSGCEAALASARLGCRTLLLTLNLDRIAWQPCNPAVGGPAKSQLTHEVDALGGEIGKVADRTYLQKRILNSSRGPAVWALRAQTDKREYAAVMKNIVENQENLTIRESMVTDLVLGANDEVIGVETYFGVGFQCKAVILTTGTFLGGKIWVGNKSMPAGRAGEFAAEGLTQTLNRLGFETGRLKTGTPARVDKRSVDYSKMLIQPGDEDVRWFSFDPEAWVEREQIPCYITRTTAETHRLIQDNLHLSPVYGGWVEAKGPRYCPSIEDKIVRFADKESHQIFIEPEGRDIPELYIQGFSTGLPENLQLQMLRTLPGLEKCVMLRPAYAVEYDYLPATQCYPTLMTKKVAGLFCAGQINGTTGYEEAAAQGLVAGINAARFVHSQEMIVFAREQSYIGTLMDDLCTKDLREPYRMLTSRSEYRLLLRSDNADQRLTTLGREIGLIDDRRWNLFTQKQANITTEKQRLQATRVKEHDEMGIAIASDTQQAIRGSITLNDLLRRPGFHYVDLDRFGLGNPNLNRAEKEGAEIDIKYYGYLARQQNQIDQIARQAHRQLPADLDYTTIDTLSKEAREKLTHVKPLTLGQAARIGGVNPADVNALLLYLELRKTKSQHEFPALA
>NZ_CP046703.1|WP_114083316.1|1702251_1703124_-|peptidase-M15
MKLTIKKQKDITRFIRKASFISIVIGIIFVLVASNEITHHQFARTSQPLNVCSPTVSSPCINTSKEITPKPFIPNPELNSNQRFLSAINQKLPTIPQPGTYEYTLLRAYGAVFVNQDVGIKLPPKDIFANEQETQEFQATLTMGHVDGTNDCYLQKSAADALNKARVQQHIPLKSGYGSGDCTRTFNTNLRFWQKYANNQILAKVQQGKETKILGLVAPPGTSQHLWGLAIDLRVGSKEQRKALNQNGWFQTVENDVPHWTYVGLDEENLPLFGFKKLLIRGITYWITPL
>NZ_CP046703.1|WP_114083317.1|1700200_1701517_-|efflux-RND-transporter-periplasmic-adaptor-subunit
MKKFSPWIFGILLASTLGSMATVYWKTQETSSQPDLTSQTILVQTKDWVVQIQANGVVQALQKINLSPEDSGRIAKLYVNEGDRVQKGQIIALMDSERLQAQVNQYQASLNKAVADLKQKVAGTRQEDIAESKARVASAEALVAASQTRLNRTIVEMQRNQVLVQEGAISRNAFEEFVTKEQEARANLEAELARLKEQRESLKKAKNGLRPEEIAQAEAEVAQAKAQLVFYQSQLNNAIIRAPFAGIITRRFAQEGDFVTPTTSASNTEGATSTSIAELSSGLEIEARIPEASIAKINRGQFVDIQTDTYPNETFKGKVSLIAPRAVQENNITFFRVKVVLSNGQDKLKSGMNVRLTFHSQTIKNALVIPLAAVTTQPNGQTGVYVIDSQNAASFQPVKVSATSGDQVQVLAGLQKGDRVLMSPPSTEKIEGVDKIGF
>NZ_CP046703.1|WP_114083318.1|1698896_1700102_-|FtsX-like-permease-family-protein
MNLLESTQMAVKTLAANKLRSMLTMLGIIIGNASVITMIAIGQGAQKFTQEKLESLGPNQLSVFAGGDNLEGLSSDVPSLFLADAQAIATMAPAVREVAPQISSNLLLSRQGRISKVNVTGTTPGILYVRNLQVHQGRFFDPIELNQNSQVVILGPVVARKLFGNENPIGQLLQMNNLSFQVIGIMQAKGAFMGDNPDDIAYVPISTMADQLVGRRSPNGIPIDYLELSAKNQDSIRAAAFQTINILTRRRGRKDFTVAANKSVQDLINQVTINLSLVLAAIAGISLFVGGIGIMNIMLVSVTERTQEIGLRKAIGATEKAILTQFLIEAIILSVAGGLVGTGIGVSGALIVAMFSPLQPSVPIGAIFLTASVSGSIGLIFGVAPARKAARLDPIAALRGI
>NZ_CP046703.1|WP_159402466.1|1715409_1715571_-|hypothetical-protein
MPKNANASLDNANASPYNVIASPDNANALPYNTIASPDNGIALPDNAIASFCI
>NZ_CP046703.1|WP_114083975.1|1715724_1716330_+|DUF411-domain-containing-protein
MSHKEFIYCWQKWLLPIVVRIVVTICLTVGVLGILGSTASTSNAQALFPDSVTANAQLVSTTKRIQDKQTPSKSTPLNATVYHSPECNCCGGWIDHLKTQGFEITDFSTPDIETVKQKYNVPDNLSSCHTAIVNGYVIEGHVPANDIKRLLQEKPNVVGLSVPQMPVGTPGMEMGNRKDPFTVFAFDGNKSVAVFNKYPSS
>NZ_CP046703.1|WP_114083976.1|1716448_1717396_-|tetratricopeptide-repeat-protein
MTEVIRTGSLNNIESIEFEKRCLHKAREIGDRNSEVICLASLGNAYQSIGEYHLAIEFYQQWLDIAKEIGDRFGEAKSLSGLGNAYQSLGKYQRAIEFYHQWLSITRKIGDRTGEAICLGSLGNTYEYLGKYDQAIEFYQQWLSITRKTGDRTGEAICLGSLGNTYESLGQYQLAIEFYHQWLEVTRLISDRNSEGMALSGLGSAYNALGQYQRAVEFHQYSLEIRRNLDDQNAEANSWFNLGLVLEKINRESEAMNAFCNARGIYHAMGIDASLQDCNHAIEHLSQNVSIIASRFWFGRWFSHLSHLIKTDSNQ
>NZ_CP046703.1|WP_114083977.1|1717645_1718038_-|hypothetical-protein
MKLLTLINSALIFASITLVSGIAVAQTATNNNTETIAINSNNLPGNSITVNYLQPFNLVTFAYQGGLKQHGIPSGEMLVFETQKRNIIANDLVKAAVNADKLPSKALNDQNYLSAVNSQLNALPDYAAAD
>NZ_CP046703.1|WP_114083978.1|1718663_1719575_+|SGNH/GDSL-hydrolase-family-protein
MQRKKWLLRTGLALLIFIMVVAAKFMDKTHPISELYVFGDSLSDTGMVFRATGGMYPPNPTYFQGRYSNGRVWIEYLAESLHLSSKQTHNFAYGGATTGNVDNNYVPSVLNQVQSFTQTHQQTNPDALYVLWAGANDYLQGVSSATIPVKNVTTAINSLTDVGAKKILVGNLPDLGQLPATRNSTNSVSLSGLTQAHNQGLRRSLKVLSQQHSDLEIVQLDANALYRDAMSATGYANANPAAFNFTNVISPCLSGDRTCSNPDQFLFWDGIHPTAAAHRIIGETAFSTIQEAGMINPRSMLVL
>NZ_CP046703.1|WP_114083979.1|1719759_1721064_+|O-acetylhomoserine-aminocarboxypropyltransferase/cysteine-synthase
MSEQYRFETLQVHAGQEPAPGTNARAVPIYQTTSYVFDDTEHGARLFALQEFGNIYTRIMNPTTDVFEKRIAALEGGVAALATASGQAAQFLAITTIAQAGDNIVSTSFLYGGTYNQFKVSLPRLGINVKFVEGDDPESFRQAIDDRTKALYVETIGNPQFNIPDFAALAHIAHENGIPLIVDNTFGAGGYLARPIEHGADIVVESATKWIGGHGTSIGGVIVDSGKFDWGNGKFPLFTEPAPGYHGLNFQEVFGTSGSFGNIAFIIRARVEGLRDFGPSLSPFNAFLLLQGLETLSLRVDRHVSNALELARWLEQQEQVLWVNYPGLPNHPYHERAKKYLRHGFGGVLNFGIKGGLEAGKAFINHVKLASHLANVGDAKTLVIHPASTTHQQLSDEEQLSAGVTPDLVRVSVGIEHIDDIKEDFQQAFGQVKI
>NZ_CP046703.1|WP_159402467.1|1721156_1721300_+|hypothetical-protein
MALRKAEIWSGQGVGGVGGVGGRGRSLTPTLPTLPTLKKQVISGLCD
>NZ_CP046703.1|WP_114083981.1|1721371_1722442_+|homoserine-O-acetyltransferase
MIYSDFISPQTQFYQLTVPFQLESGEVLIGVQIAYRSWGELNAQGDNGVLICHALTGSADADDWWEPLFGSGKAFNPDRNFIVCSNILGSCYGTTGPTTINPTTRKPYGVSFPKITIRDMVRLQAVLLEYLGVQSLRFVIGGSLGGMQSLEWALLYPDKVKGIAPIAVSGRHSAWCIGLSEAQRQAIYADPNWQGGNYTLDTPPNQGLAVARMMAMSTYRSWDSFTTRFGRQYDPSEKFAIASYLQHQGQKLTERFDANTYITLTHAMDDHDIARDRTTPNLSDYESVLGSIQQPTLVVAIDSDILYPPVEQQELANLIPNAQLSWLKSTHGHDAFLIDMAALNEIIQQNHKFVLF
>NZ_CP046703.1|WP_114083982.1|1722597_1723929_-|FAD-dependent-oxidoreductase
MRIAIIGGGGSGMATAYLLDKQGHHVTVFERQPMLGGHIRTLNKNVKPNQSDCNEMLESGVLEFPTVFHSFVALMQELGVALEPIRVGSALFPQNGSPFFSKVTNENNYTGIQRLIEYLRFDTIHTRSLGLWLKTRFAQMEDFYNQPLSQYVNNQSISNTWLKLLTMYSYSMPFELIDNFPAEMGIPMLRDYLAVKWLRIKGGVYSYIEKILERFKGEILLNVEIVNISRSADGVKIQRSQGEIQEFDKVVFATPPDQVMALLADPTEAEIKRFSDWKANYATTTIHTDTSMYDHHHIHHPSEFDFFQTDTQWGYNSYLNQLCGISSPQHYFLSFQLEGLIDPAHIIHTQEHHTPLYTTESFRYRDEVVATNGENNTYYAGAYLGDGLHEGAIASAFRVAQLIGSPLAVSISAFNDGNPDTVNIAADTAGIGKYLTHPRSHRS
>NZ_CP046703.1|WP_114083983.1|1724094_1725657_-|NAD(P)/FAD-dependent-oxidoreductase
MKADYLIVGSGLSALVFGALMANSGKTVQILEAHEHPGGFGHTFMMAKKYTFNAQFHYVWDCGEGQTVNRVLKKLGLDREVTFERYDPDGFDHMRMPGYALDMPSESEELIQRLSKLFPEYSVGGASRSENRIRQFVNDVEKTSAGLKRLAPPVKPIELLKHPGEVFCTVQYLNSTLQDVFDKFQLPQAAQTLLALQWPDFLLPPNQLSFYAWVALFKGYQAGAFYPTQHFEHVINSLVKVIESNGGQVLLNHEVTNFRVIDKTVTGVEAMDLNTHQTHEFTGDTVICNIDPKKAAKMIGESHFSKTVRRKLNYEYSASNYMAYCVVKDLDLRDYGFGKWNLFHTGHQDLNEAFAQMYEHNDFSNPSFAITTPTLLTQASRDCPEDCQIVEFLTVANYNYFKQLRQSDRKAYNQKKQEIFDSILDVVEKEYIPNFRKHLVFHITGSPTTNERYCWCPNGNSYGSSLTPRNMGLGRLNHETSLNHFYFCNASSGYPGFAPTFWTGALLYQRLSGDVLLGNS

Crispr_ID: NZ_CP046703_5

• CRISPR_ID: NZ_CP046703_5
• CRISPR_location: 2316082-2316190
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP046703_5

Consensus_repeat	Method
GGTTAGTACCGGAAGCAGCAGGTAGAGCCATTTCGCT	CRISPRCasFinder

spacers of NZ_CP046703_5

>5.1|2316119|35|NZ_CP046703|CRISPRCasFinder
TTTTGGATGTCAACTTCAGCTTTGCTACCACTAGC

CRISPR arrays and Neighbor proteins around NZ_CP046703_5

CRISPR arrays

The CRISPR arrays of NZ_CP046703_5

>merge|NZ_CP046703|5|2316082-2316190|CRISPRCasFinder
GGTTAGTACCGGAAGCAGCAGGTAGAGCCATTTCGCTTTTTGGATGTCAACTTCAGCTTTGCTACCACTAGCGGTTAGTACCGGAAGCAGCAGGTAGAGCCATTTCGCT

>NZ_CP046703|5|5|2316082-2316190|CRISPRCasFinder
GGTTAGTACCGGAAGCAGCAGGTAGAGCCATTTCGCT	TTTTGGATGTCAACTTCAGCTTTGCTACCACTAGC
GGTTAGTACCGGAAGCAGCAGGTAGAGCCATTTCGCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046703.1|WP_012412473.1|2306638_2306962_+|thioredoxin	unknown	unknown	gnl|CDD|200072
NZ_CP046703.1|WP_114084303.1|2310589_2311888_+|MFS-transporter	unknown	unknown	gnl|CDD|340913
NZ_CP046703.1|WP_114084293.1|2322073_2322718_+|restriction-endonuclease-subunit-R	unknown	unknown	unknown
NZ_CP046703.1|WP_114084300.1|2313796_2314762_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379276
NZ_CP046703.1|WP_012412483.1|2317483_2317744_-|MoaD/ThiS-family-protein	unknown	unknown	gnl|CDD|340452
NZ_CP046703.1|WP_114084290.1|2324341_2324782_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114084299.1|2315096_2315795_+|thiol:disulfide-oxidoreductase	unknown	unknown	gnl|CDD|172475
NZ_CP046703.1|WP_114084301.1|2312938_2313706_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NZ_CP046703.1|WP_114084306.1|2307126_2307921_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|187602
NZ_CP046703.1|WP_114084295.1|2319072_2319753_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|276809
NZ_CP046703.1|WP_114084304.1|2309641_2310307_+|nitroreductase	unknown	unknown	gnl|CDD|223849
NZ_CP046703.1|WP_114084294.1|2319870_2321841_-|acetate--CoA-ligase	unknown	unknown	gnl|CDD|234677
NZ_CP046703.1|WP_159402486.1|2311895_2312048_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114084305.1|2308182_2309295_+|alkene-reductase	unknown	unknown	gnl|CDD|239243
NZ_CP046703.1|WP_114084297.1|2317863_2318622_-|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|368559
NZ_CP046703.1|WP_114084291.1|2323563_2324274_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114084302.1|2312214_2312904_+|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|187631
NZ_CP046703.1|WP_114084292.1|2322740_2323490_+|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|99749
NZ_CP046703.1|WP_114084298.1|2316415_2317273_+|glycerol-acyltransferase	unknown	unknown	gnl|CDD|153249
NZ_CP046703.1|WP_114084296.1|2318708_2318942_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046703.1|WP_012412473.1|2306638_2306962_+|thioredoxin	gnl|CDD|200072	TIGR01068, Thioredoxin-like_protein_slr0233, thioredoxin. Several proteins, such as protein disulfide isomerase, have two or more copies of a domain closely related to thioredoxin. This model is designed to recognize authentic thioredoxin, a small protein that should be hit exactly once by this model. Any protein that hits once with a score greater than the second (per domain) trusted cutoff may be taken as thioredoxin. [Energy metabolism, Electron transport].	2.59382e-54
NZ_CP046703.1|WP_114084303.1|2310589_2311888_+|MFS-transporter	gnl|CDD|340913	cd17355, MFS_YcxA_like, MFS-type transporter YcxA and similar proteins of the Major Facilitator Superfamily of transporters. This group is composed of uncharacterized bacterial MFS-type transporters including Bacillus subtilis YcxA and YbfB. YcxA has been shown to facilitate the export of surfactin in B. subtilis. The YcxA-like group belongs to the Monocarboxylate transporter -like (MCT-like) family of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.77437e-103
NZ_CP046703.1|WP_114084300.1|2313796_2314762_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|379276	pfam13578, Methyltransf_24, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.16434e-16
NZ_CP046703.1|WP_012412483.1|2317483_2317744_-|MoaD/ThiS-family-protein	gnl|CDD|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	4.07252e-24
NZ_CP046703.1|WP_114084299.1|2315096_2315795_+|thiol:disulfide-oxidoreductase	gnl|CDD|172475	PRK13972, PRK13972, GSH-dependent disulfide bond oxidoreductase; Provisional.	1.16719e-86
NZ_CP046703.1|WP_114084301.1|2312938_2313706_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	2.38182e-23
NZ_CP046703.1|WP_114084306.1|2307126_2307921_+|SDR-family-oxidoreductase	gnl|CDD|187602	cd05344, BKR_like_SDR_like, putative beta-ketoacyl acyl carrier protein [ACP] reductase (BKR)-like, SDR. This subgroup resembles the SDR family, but does not have a perfect match to the NAD-binding motif or the catalytic tetrad characteristic of the SDRs. It includes the SDRs, Q9HYA2 from Pseudomonas aeruginosa PAO1 and APE0912 from Aeropyrum pernix K1. BKR catalyzes the NADPH-dependent reduction of ACP in the first reductive step of de novo fatty acid synthesis (FAS). FAS consists of four elongation steps, which are repeated to extend the fatty acid chain through the addition of two-carbo units from malonyl acyl-carrier protein (ACP): condensation, reduction, dehydration, and a final reduction. Type II FAS, typical of plants and many bacteria, maintains these activities on discrete polypeptides, while type I FAS utilizes one or two multifunctional polypeptides. BKR resembles enoyl reductase, which catalyzes the second reduction step in FAS. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRS are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes have a 3-glycine N-terminal NAD(P)(H)-binding pattern (typically, TGxxxGxG in classical SDRs and TGxxGxxG in extended SDRs), while substrate binding is in the C-terminal region. A critical catalytic Tyr residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering), is often found in a conserved YXXXK pattern. In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) or additional Ser, contributing to the active site. Substrates for these enzymes include sugars, steroids, alcohols, and aromatic compounds. The standard reaction mechanism is a proton relay involving the conserved Tyr and Lys, as well as Asn (or Ser). Some SDR family members, including 17 beta-hydroxysteroid dehydrogenase contain an additional helix-turn-helix motif that is not generally found among SDRs.	1.49025e-60
NZ_CP046703.1|WP_114084295.1|2319072_2319753_-|tetratricopeptide-repeat-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	2.37041e-23
NZ_CP046703.1|WP_114084304.1|2309641_2310307_+|nitroreductase	gnl|CDD|223849	COG0778, NfnB, Nitroreductase [Energy production and conversion].	4.21372e-37
NZ_CP046703.1|WP_114084294.1|2319870_2321841_-|acetate--CoA-ligase	gnl|CDD|234677	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional.	0
NZ_CP046703.1|WP_114084305.1|2308182_2309295_+|alkene-reductase	gnl|CDD|239243	cd02933, OYE_like_FMN, Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Members of OYE family include 12-oxophytodienoate reductase, pentaerythritol tetranitrate reductase, morphinone reductase, and related enzymes.	0
NZ_CP046703.1|WP_114084297.1|2317863_2318622_-|Uma2-family-endonuclease	gnl|CDD|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	3.24836e-13
NZ_CP046703.1|WP_114084302.1|2312214_2312904_+|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|187631	cd05373, SDR_c10, classical (c) SDR, subgroup 10. This subgroup resembles the classical SDRs, but has an incomplete match to the canonical glycine rich NAD-binding motif and lacks the typical active site tetrad (instead of the critical active site Tyr, it has Phe, but contains the nearby Lys). SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	1.99051e-91
NZ_CP046703.1|WP_114084292.1|2322740_2323490_+|Uma2-family-endonuclease	gnl|CDD|99749	cd06260, DUF820, Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of nucleases.	6.23129e-19
NZ_CP046703.1|WP_114084298.1|2316415_2317273_+|glycerol-acyltransferase	gnl|CDD|153249	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this suubgroup are such LPLATs as 2-acylglycerol O-acyltransferase (MGAT), and similar proteins.	7.87832e-34

Protein sequences

>NZ_CP046703.1|WP_114084299.1|2315096_2315795_+|thiol:disulfide-oxidoreductase
MIDLYYWTTPNGHKITIFLEEVGLQYTINPVNIGAGDQFKPEFLKISPNNRIPAIVDHEPVDGGAPISVFESGAILLYLAEKTGKLIPQDLRQRTQVLEWLFWQMSGLGPMAGQNHHFSAYAPEKIEYAINRYVNETGRLYGVLNKQLADREFVAGDYSIADIAAYPWIVPYERQSQNLEDFPHLKRWFETIKARPATIRAYEKAEALKTQPLDPDKSRDLLFNQSAKTIQP
>NZ_CP046703.1|WP_114084300.1|2313796_2314762_-|class-I-SAM-dependent-methyltransferase
MSEKTVKVIEGNLLPKGDYVSSGFSTIQPDLYFPNIILGNKYDSFWLYLRRDITHNWYVDKRRQKVGFVSRDEAHILYNTALKFRGEKALEIGCWMGWSACHLALGGVELDVIDPMLSEQLFNESVTESLKSAGVKESVNLIPGCSPEKVEEIANKFQRKWSLIFIDGNHEAPAPLNDAIICEQFAEADALILFHDLASPDVGQGLDYFRDKGWNTMVYQTMQIMGVAWRGNVEPVIHQPDPNINWPLPPHLQGYFVSGSVKTATEDKFAEILRAVRPFTLLSEAKLFSLYSQAKQLYCYLFWLPKMLLQAIARIKPIKGN
>NZ_CP046703.1|WP_114084301.1|2312938_2313706_+|class-I-SAM-dependent-methyltransferase
MKIDFGATAVDYAKHRAGFPSSLFNKLSEYGIGLPGQNIVDLGTGTGTLARGFADRGAYVIGIDPSASLLEQARQLSESTQIKVDYRVATAENTELPDASADVITAGQCWHWFDRPRAVQEVTRILRKNGSIAIAHFDWIPLKGNVVEATEQLIQAHNPAWNLAGGNGLHPLWLQDIGEVGFREIRTFSYDVFVSYTQVAWRGRIRASAGVGASLTPEKVEIFDQELATLLEAKFPTPILQVHHRVWAAIAKSPL
>NZ_CP046703.1|WP_114084302.1|2312214_2312904_+|SDR-family-NAD(P)-dependent-oxidoreductase
MATTALIVGAGSGLSASLARLFAKEGFTVALAARQIEKLTQLTSEIDAVSFAADVSKPNEVEQLFIDIDNKIGSPNVVIYNPSFRVRGPLIDLDPGEVAKTLDVTAYGGFLVAQAATKRFLQLGGGAIFFTGASASIKGYAQSAPFAMGKFALRGLAQSIARELAPKNIHVAHFVIDGAIRSAVRQDPVDNPDSTLDPDAIAQTYLSILRQPRSAWTYEVELRPWVENF
>NZ_CP046703.1|WP_159402486.1|2311895_2312048_-|hypothetical-protein
MKRNPTLPPNFMLGYAIAAPNLQNLRMSYGITNRRGTEGTEKSEFETYFA
>NZ_CP046703.1|WP_114084303.1|2310589_2311888_+|MFS-transporter
MSLASFLARRSFHYAWIVAGLTFLALLVAAGIRSAPGVFIVPLEQEFGWSRATISLAISINLVLYGLIGPFAATVMERIGIRRMMVFSLAVIALGVGLTTLMSASWQLVLLWGVVVGSGSGVIALVLGAIVVNRWFSEKRGLVLGILTASTATGQLVFLPMLASVADRFGWRTAALALTGAALLIIPAIAAFMRDRPADVGLRPFGDNSETVEISQPRANSIASTLNALWLGMRKRDFWLLFGSFFICGASTNGLIGTHLIPACIDHGIPEVKAAGLLAIMGLFDFFGTTMSGWLSDRWNNRYLLCWYYGLRGLSLIFLPFSFNFSFYGLSIFAVFYGLDWIATVPPTVRLVANTFGKENVGVMFGWIVAGHQLGAATAAFGAGVLRTWTGSYLQAFILSGILCLIAAVGVLQIGKTPTKGNSQLSSVTLKS
>NZ_CP046703.1|WP_114084304.1|2309641_2310307_+|nitroreductase
MSSITQTQALDVPSAIAQRRSIKTFTTDPIAPELLKQLVELTVAAPSSFNIQSWQIILVQDEAQKAALSAASWNQQQIVQAPVTFVFAADPNAGEQNLLPILEQAAGTGAWNEGTVNYFKSAIPQFQAGLGDKRREYAIKDAIIAATHLVLAAESLGLSTCFMNGWVEDQVKQVIGAGDNPDLAIAVVVPVGYAAEPRLNPGRLPFSSNVSVDRIGNPYAG
>NZ_CP046703.1|WP_114084305.1|2308182_2309295_+|alkene-reductase
MTSDINLFSSYQLGNLELPNRIVMAPLTRNRASEGNVPYELNATYYAQRASAGLIISEAAQITPEGQGYPATPGIHSSEQIEGWKLVTDAVHREGGRIFMQLWHVGRISHPDLQPNGALPVAPSAIAPKGEAATYEGPKSFVTPRALETSEIPQIVEQYRQGAANALAAGFDGVEIHSANGYLIDQFLRDRTNQRTDKYGGSIENRTRFLLEVTEAVTSVWDSNRVGVRFSPSGTFNDIGDSNPLETFGYATQALNQFNLAYLHLYEATEADIRHGGIIVPTSHIRDRFTGTLIVNGGYTREKGDAVLANKAADLVAFGTLFISNPDLPRRLALNAPLNEANQATFYGGGEQGYTDYPFWSAANEAVAQA
>NZ_CP046703.1|WP_114084306.1|2307126_2307921_+|SDR-family-oxidoreductase
MDLKLHGKSALVSGSTAGIGLATALGLAQEGASVIVNGRSEERVAQAIAKIQQSTPDAKVSGVVADTSTASGVEELFQKVPHVDILINNVGIYEPKTFFDITDEDWLNIFQVNVLSGVRLSRQYLQKQLEQNWGRIIFISSESAIQIPVEMIHYGTTKTAQLAIARGLAEMTVGTGVTVNSVLPGPTRSEGVEEFIINLAQERGISPTEVEAEFFQNVRPSSLIKRFATNEEVAAIVVYLSSPVASATNGAALRVDGGVIRSIV
>NZ_CP046703.1|WP_012412473.1|2306638_2306962_+|thioredoxin
MSSITNVTEATFKQEVLESEIPVLVDFWAPWCGPCRMVGPVVDEVAAEYEGQVKFVKLNTDQNPTVASHYGIRSIPTLMVFKGGRQVDTVVGAVPKTTLNKTLAQHL
>NZ_CP046703.1|WP_114084298.1|2316415_2317273_+|glycerol-acyltransferase
MSKKQHLLKKKPGWSLDERDPKFIESLMPLLGFFYKYYFQVQTSGWENIPSQEKVLFVGSHNGGLAAPDMGMVMYDWFRRFGTEKPVYGLMHPKAWQVSQPLAQIAAKAGAIIAHPKMAYTALHSGASVLVYPGGAEDVFRPHYLRNKIYFAGRQGFIKLALRENVPIVPVISWGAHDTLIVLADFYKVVQQLHEWGMPWLLGIDPEVFPIYLGLPWGLAIGPLPNIPLPVPMYTRVCPPIVFERYGREAASDRHYVNECYELVVSQMQEELDNLVKITAESNSR
>NZ_CP046703.1|WP_012412483.1|2317483_2317744_-|MoaD/ThiS-family-protein
MSKSAITVTVKLFAAYQEAFKVSELVLEFPNSMPVKAVCDRLIAEHPELSQWRDITRFGINLIFVEPDTLLQDGDEVVLIPPVSGG
>NZ_CP046703.1|WP_114084297.1|2317863_2318622_-|Uma2-family-endonuclease
MTSLSALTLPDHTQLPDSDGTFVKNWQEHPQSILLTDSIKLVLEELHPDSQYCIGQDLGIYWRLTDPPEKGAEAPDWFYVPNVPPTLEGKTRRSYVLWKEYVAPLIVIEFVSGDGSEERNNTPPSQGEGGNVGKFWVYEQAIRVPYYGIYEVAKAQVEVYHLIDNTYERMQPNERGHYPIVPMGVELGIWQGFYQNAELPWLRWWNAQGNLLLTGEERAVIERQKRERIVEKLRTLSAEQLNALGIDLEMLD
>NZ_CP046703.1|WP_114084296.1|2318708_2318942_-|hypothetical-protein
MGWDRKLTLLKASKQNNSIAMNEIFLLARETVKVIFQMDGGYTKVVWERSANDCENIENIHNNRNSFFHIERLTFVI
>NZ_CP046703.1|WP_114084295.1|2319072_2319753_-|tetratricopeptide-repeat-protein
MKLKSKPKSAFVQPFSCMMLSILTVISLSPLALAVSGKVSLHSPEQNAQRQPQKLAQFSDTGPSERSQMLQQANALFNQGDLTGAEENFRKLIKKFPDDAFGHFQLGNVLFRQKKPEEAISAYQEAIRLQSKYALAYNAIGMVYASQSRWEEAITEYKKALEINPNYGEGLTNFALALWQTNKKDEALSSLEKALNIFKSQNRGEKVNQVERILKEIKTAEDPSVS
>NZ_CP046703.1|WP_114084294.1|2319870_2321841_-|acetate--CoA-ligase
MSEPNIESILQENRLFHPPSEFSQNAHIKSLDDYKRLYEKAKADPQQFWADLAGTELEWFQKWDTVLDWQPPFAKWFVGGKMNISYNCLDRHLTTWRKNKAALIWEGEPGDSRTLTYAQLHREVCQFANVLKQLGVQKGDRVGIYMPMIPEAAIAMLACARIGAPHGVVFGGFSAEALRDRLIDATAKLVITADGGWRKDAIVPLKEQVDKALADGAVPSVENVLVVKRTGQETYMQGGRDHWWHDLQKGVSADCPAEPMDSEDMLFVLYTSGSTGKPKGVVHTTAGYNLYTHITTKWIFDLQDTDVYWCTADVGWITGHSYIVYGPLSNGATTVMYEGAPRASNPGCFWDVIEKYGVNIFYTAPTAIRAFIKMGEHHPNARNLSSLRLLGSVGEPINPEAWMWYQKVIGGDRCPIVDTWWQTETGGIMITPLPGAIPTKPGSATLPFPGIIADVVDLEGNTVPNNEGGYLAVRHPWPGMMRTVYGDPERFRRTYWEHIPPQDGKYTYFAGDGARQDEDGYFWVMGRVDDVLNVSGHRLGTMEVESALVSHPAVAEAAVVGKPDELKGEEVVAFVTLEGTYQGSEELSKELKQHVVKEIGAIARPGEIRFTDALPKTRSGKIMRRLLRNLAAGQEVSGDTSTLEDRSVLDKLREGT
>NZ_CP046703.1|WP_114084293.1|2322073_2322718_+|restriction-endonuclease-subunit-R
MTLTVEASSLSLNDVHRFLKLEKLSNGSFTDFLRLEPLSDFEQQDLLRIRDDFDRYLSAGKISEGLVKFITIAPLMRLAGFYDVPIRLTMEDSIAIAVEDEDRRITGRMDILAINSFQSNIAPPFWVVVIETKNSAIEVGEGLPQLLTYAFKSLEQQPSVWGLVTNGLRYQFVYLRHDEQSNYQLMPLLSLNESPDAIELLQVFKAICKLANFQ
>NZ_CP046703.1|WP_114084292.1|2322740_2323490_+|Uma2-family-endonuclease
MSEPATLEFISNGISEDEVIFPPGDILSDEPPLESDLHRDQIDLLIRILKLWWRKRQDFYASGNLTIYYSPNQKTSEYFRGPDFFVVLGTQKKDRKSWVVWQEDGKYPNVIVEILSSSTTALDKGLKKQVYQDTFRTPDYFWFDPVTMELQGFHLVDGKYQEIQVTTDGRLWSQQLELYLGVYEGKLRFFTTENQLILSSEELAEQERLRAHQAEERAQESEERAQQAEQELARLREVLRTKGIDLENI
>NZ_CP046703.1|WP_114084291.1|2323563_2324274_+|hypothetical-protein
MKVGPRLQATEIKDKLKSLTLQASSVDHNLARRLDEINRWVKNIKPGSLTAKPFVIAFLLEVITDSTIWLIIKSLPSEEEQKAKFELMTPIERYWYGYLFPRWINASDSKFYIWKQKLMAGEFNQVDDDIIKSIAQDVVSREGSFWQRYIADLSMATDLIVSSRNNQPLCIQVTSVSEELNYQKYQAWQNTLRSWEIERGLFLSYNPKDTNFVNQLVNVALYNSDYLSGGKYLKFS
>NZ_CP046703.1|WP_114084290.1|2324341_2324782_+|hypothetical-protein
MANKRETHCNNQVDTFAEALATARQMQQNWLTYGVNFVNFYVEDVDGDWLETWGHDEILGNSQLDTIKEFLVSNDSVAVKVRQYLGERSLFDFAVNLEESWRISETNNRLSAVKNLLAGEGHSIDTDDIRLLDLADSLVVKLAEIL

Crispr_ID: NZ_CP046703_6

• CRISPR_ID: NZ_CP046703_6
• CRISPR_location: 2342811-2343645
• CRISPR_type: Orphan
• Repeat_type: I-D,II-B
• Spacer_info: 11 spacers

Consensus repeat of NZ_CP046703_6

Consensus_repeat	Method
GTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT	PILER-CR
GTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT	CRISPRCasFinder
GTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT	CRT

spacers of NZ_CP046703_6

>6.1|2342848|34|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT
TATAGGGGATATGGTAGAAGTGTTAGTGTAGACT
>6.2|2342919|35|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT
CGAATAATCCTGAATGTCCTCGCTGGGTCACTCAA
>6.3|2342991|35|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT
TTAAAGCCGGGAAAATAAAAGTAACTTATACACGT
>6.4|2343063|35|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT
TTTGGGTGTGGCTAGTCCTTGGATTACCCCACAGG
>6.5|2343135|43|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT
AAGTAAGGGAATTTTTAGCGGCGGGTCGTTTCATGGTTCGGCT
>6.6|2343215|35|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT
TGTATCCCTTTTTGGGTGGTGAAGTTGATAGTTCA
>6.7|2343287|34|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT
TCCAATCTCTAAAAGTTACAGTAGATAAAAATGC
>6.8|2343358|34|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT
GACCCCATTGGTTCATCAATCGCTCGAATTTTCA
>6.9|2343429|36|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT
TTTCAGACAATCACTGATGGATGTGCTTTTGAATTA
>6.10|2343502|36|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT
GGTGTTAAGGCTCAATCGGTTTTCACTTCACCACTT
>6.11|2343575|34|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT
TTTTGTGAAATAAACTCTAGTAATGAAAACTTTA

CRISPR arrays and Neighbor proteins around NZ_CP046703_6

CRISPR arrays

The CRISPR arrays of NZ_CP046703_6

>merge|NZ_CP046703|6|2342811-2343645|PILER-CR,CRISPRCasFinder,CRT
GTTTTAATCCCTAATAGGGATTTTGATGAATTGCAATTATAGGGGATATGGTAGAAGTGTTAGTGTAGACTGTTTCAATCCCTAATAGGGATTTTGATGAATTGCAATCGAATAATCCTGAATGTCCTCGCTGGGTCACTCAAGTTTCAATCCCTAATAGGGATTTTGATGAATTGCAATTTAAAGCCGGGAAAATAAAAGTAACTTATACACGTGTTTCAATCCCTAATAGGGATTTTGATGAATTGCAATTTTGGGTGTGGCTAGTCCTTGGATTACCCCACAGGGTTTCAATCCCTAATAGGGATTTTGATGAATTGCAATAAGTAAGGGAATTTTTAGCGGCGGGTCGTTTCATGGTTCGGCTGTTTCAATCCCTAATAGGGATTTTGATGAATTGCAATTGTATCCCTTTTTGGGTGGTGAAGTTGATAGTTCAGTTTCAATCCCTAATAGGGATTTTGATGAATTGCAATTCCAATCTCTAAAAGTTACAGTAGATAAAAATGCGTTTCAATCCCTAATAGGGATTTTGATGAATTGCAATGACCCCATTGGTTCATCAATCGCTCGAATTTTCAGTTTCAATCCCTAATAGGGATTTTGATGAATTGCAATTTTCAGACAATCACTGATGGATGTGCTTTTGAATTAGTTTCAATCCCTAATAGGGATTTTGATGAATTGCAATGGTGTTAAGGCTCAATCGGTTTTCACTTCACCACTTGTTTCAATCCCTAATAGGGATTTTGATGAATTGCAATTTTTGTGAAATAAACTCTAGTAATGAAAACTTTAGTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT

>NZ_CP046703|6|1|2342811-2343645|PILER-CR
GTTTTAATCCCTAATAGGGATTTTGATGAATTGCAAT	TATAGGGGATATGGTAGAAGTGTTAGTGTAGACT
GTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT	CGAATAATCCTGAATGTCCTCGCTGGGTCACTCAA
GTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT	TTAAAGCCGGGAAAATAAAAGTAACTTATACACGT
GTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT	TTTGGGTGTGGCTAGTCCTTGGATTACCCCACAGG
GTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT	AAGTAAGGGAATTTTTAGCGGCGGGTCGTTTCATGGTTCGGCT
GTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT	TGTATCCCTTTTTGGGTGGTGAAGTTGATAGTTCA
GTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT	TCCAATCTCTAAAAGTTACAGTAGATAAAAATGC
GTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT	GACCCCATTGGTTCATCAATCGCTCGAATTTTCA
GTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT	TTTCAGACAATCACTGATGGATGTGCTTTTGAATTA
GTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT	GGTGTTAAGGCTCAATCGGTTTTCACTTCACCACTT
GTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT	TTTTGTGAAATAAACTCTAGTAATGAAAACTTTA
GTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT

>NZ_CP046703|6|6|2342811-2343645|CRISPRCasFinder
GTTTTAATCCCTAATAGGGATTTTGATGAATTGCAAT	TATAGGGGATATGGTAGAAGTGTTAGTGTAGACT
GTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT	CGAATAATCCTGAATGTCCTCGCTGGGTCACTCAA
GTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT	TTAAAGCCGGGAAAATAAAAGTAACTTATACACGT
GTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT	TTTGGGTGTGGCTAGTCCTTGGATTACCCCACAGG
GTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT	AAGTAAGGGAATTTTTAGCGGCGGGTCGTTTCATGGTTCGGCT
GTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT	TGTATCCCTTTTTGGGTGGTGAAGTTGATAGTTCA
GTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT	TCCAATCTCTAAAAGTTACAGTAGATAAAAATGC
GTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT	GACCCCATTGGTTCATCAATCGCTCGAATTTTCA
GTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT	TTTCAGACAATCACTGATGGATGTGCTTTTGAATTA
GTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT	GGTGTTAAGGCTCAATCGGTTTTCACTTCACCACTT
GTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT	TTTTGTGAAATAAACTCTAGTAATGAAAACTTTA
GTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT

>NZ_CP046703|6|1|2342811-2343645|CRT
GTTTTAATCCCTAATAGGGATTTTGATGAATTGCAAT	TATAGGGGATATGGTAGAAGTGTTAGTGTAGACT
GTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT	CGAATAATCCTGAATGTCCTCGCTGGGTCACTCAA
GTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT	TTAAAGCCGGGAAAATAAAAGTAACTTATACACGT
GTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT	TTTGGGTGTGGCTAGTCCTTGGATTACCCCACAGG
GTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT	AAGTAAGGGAATTTTTAGCGGCGGGTCGTTTCATGGTTCGGCT
GTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT	TGTATCCCTTTTTGGGTGGTGAAGTTGATAGTTCA
GTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT	TCCAATCTCTAAAAGTTACAGTAGATAAAAATGC
GTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT	GACCCCATTGGTTCATCAATCGCTCGAATTTTCA
GTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT	TTTCAGACAATCACTGATGGATGTGCTTTTGAATTA
GTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT	GGTGTTAAGGCTCAATCGGTTTTCACTTCACCACTT
GTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT	TTTTGTGAAATAAACTCTAGTAATGAAAACTTTA
GTTTCAATCCCTAATAGGGATTTTGATGAATTGCAAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046703.1|WP_114084265.1|2355089_2356229_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NZ_CP046703.1|WP_114084394.1|2340559_2341183_+|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|368559
NZ_CP046703.1|WP_114084275.1|2341282_2341618_-|XisI-protein	unknown	unknown	gnl|CDD|370165
NZ_CP046703.1|WP_114084392.1|2353817_2354909_+|calcium/proton-exchanger	unknown	unknown	gnl|CDD|273043
NZ_CP046703.1|WP_114084272.1|2343955_2344978_-|isopenicillin-N-synthase-family-oxygenase	unknown	unknown	gnl|CDD|226022
NZ_CP046703.1|WP_114084266.1|2350572_2353290_-|DUF3536-domain-containing-protein	unknown	unknown	gnl|CDD|212109
NZ_CP046703.1|WP_114084269.1|2347623_2348538_+|hypothetical-protein	unknown	unknown	gnl|CDD|367100
NZ_CP046703.1|WP_114084278.1|2338052_2338595_-|hypothetical-protein	unknown	unknown	gnl|CDD|276809
NZ_CP046703.1|WP_114084273.1|2342039_2342588_-|shikimate-kinase	unknown	unknown	gnl|CDD|234654
NZ_CP046703.1|WP_114084268.1|2348690_2349788_+|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl|CDD|223745
NZ_CP046703.1|WP_114084279.1|2337141_2338026_-|DUF3153-domain-containing-protein	unknown	unknown	gnl|CDD|371485
NZ_CP046703.1|WP_114084271.1|2345143_2346634_-|BamA/TamA-family-outer-membrane-protein	unknown	unknown	gnl|CDD|227116
NZ_CP046703.1|WP_114084274.1|2341605_2342022_-|fatty-acid-oxidation-protein-subunit-alpha	unknown	unknown	gnl|CDD|370136
NZ_CP046703.1|WP_114084280.1|2335882_2336500_-|FMN-dependent-NADH-azoreductase	unknown	unknown	gnl|CDD|224103
NZ_CP046703.1|WP_159402487.1|2335690_2335834_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114084270.1|2347088_2347556_+|DUF4870-domain-containing-protein	unknown	unknown	gnl|CDD|225833
NZ_CP046703.1|WP_114084276.1|2339896_2340376_+|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|224276
NZ_CP046703.1|WP_114084393.1|2349795_2350041_+|HNH-endonuclease	unknown	unknown	gnl|CDD|372995
NZ_CP046703.1|WP_012412521.1|2356396_2357827_-|NADP-dependent-phosphogluconate-dehydrogenase	unknown	unknown	gnl|CDD|236453
NZ_CP046703.1|WP_114084277.1|2338872_2339769_-|acetylglutamate-kinase	unknown	unknown	gnl|CDD|239783

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046703.1|WP_114084394.1|2340559_2341183_+|Uma2-family-endonuclease	gnl|CDD|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	1.83231e-41
NZ_CP046703.1|WP_114084275.1|2341282_2341618_-|XisI-protein	gnl|CDD|370165	pfam08869, XisI, XisI protein. The fdxN element, along with two other DNA elements, is excised from the chromosome during heterocyst differentiation in cyanobacteria. The xisH as well as the xisF and xisI genes are required.	4.2928e-57
NZ_CP046703.1|WP_114084392.1|2353817_2354909_+|calcium/proton-exchanger	gnl|CDD|273043	TIGR00378, cax, calcium/proton exchanger (cax). [Transport and binding proteins, Cations and iron carrying compounds].	4.37467e-133
NZ_CP046703.1|WP_114084277.1|2338872_2339769_-|acetylglutamate-kinase	gnl|CDD|239783	cd04250, AAK_NAGK-C, AAK_NAGK-C: N-Acetyl-L-glutamate kinase - cyclic (NAGK-C) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine biosynthesis found in some bacteria and photosynthetic organisms using the non-acetylated, cyclic route of ornithine biosynthesis. In this pathway, glutamate is first N-acetylated and then phosphorylated by NAGK to give phosphoryl NAG, which is converted to NAG-ornithine. There are two variants of this pathway. In one, typified by the pathway in Thermotoga maritima and Pseudomonas aeruginosa, the acetyl group is recycled by reversible transacetylation from acetylornithine to glutamate. The phosphorylation of NAG by NAGK is feedback inhibited by arginine. In photosynthetic organisms, NAGK is the target of the nitrogen-signaling protein PII. Hexameric formation of NAGK domains appears to be essential to both arginine inhibition and NAGK-PII complex formation. NAGK-C are members of the Amino Acid Kinase Superfamily (AAK).	6.24212e-172
NZ_CP046703.1|WP_114084266.1|2350572_2353290_-|DUF3536-domain-containing-protein	gnl|CDD|212109	cd10797, GH57N_APU_like_1, N-terminal putative catalytic domain of mainly uncharacterized prokaryotic proteins similar to archaeal thermoactive amylopullulanases; glycoside hydrolase family 57 (GH57). This subfamily of mainly uncharacterized bacterial proteins, shows high sequence homology to GH57 archaeal thermoactive amylopullulanases (APU, E.C 3.2.1.1/41). Thermoactive APUs are type II pullulanases with both pullulanolytic and amylolytic activities. They have an acid pH optimum and the presence of Ca2+ might increase their activity, thermostability, and substrate affinity.	0
NZ_CP046703.1|WP_114084269.1|2347623_2348538_+|hypothetical-protein	gnl|CDD|367100	pfam02485, Branch, Core-2/I-Branching enzyme. This is a family of two different beta-1,6-N-acetylglucosaminyltransferase enzymes, I-branching enzyme and core-2 branching enzyme. I-branching enzyme is responsible for the production of the blood group I-antigen during embryonic development. Core-2 branching enzyme forms crucial side-chain branches in O-glycans. This is a fmmily of glycosyl-transferases that are Type II membrane proteins that are found in the endoplasmic reticulum (ER) and Golgi apparatus.	1.0487e-23
NZ_CP046703.1|WP_114084278.1|2338052_2338595_-|hypothetical-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	9.09656e-05
NZ_CP046703.1|WP_114084273.1|2342039_2342588_-|shikimate-kinase	gnl|CDD|234654	PRK00131, aroK, shikimate kinase; Reviewed.	5.34739e-80
NZ_CP046703.1|WP_114084268.1|2348690_2349788_+|Gfo/Idh/MocA-family-oxidoreductase	gnl|CDD|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	2.3485e-73
NZ_CP046703.1|WP_114084279.1|2337141_2338026_-|DUF3153-domain-containing-protein	gnl|CDD|371485	pfam11353, DUF3153, Protein of unknown function (DUF3153). This family of proteins with unknown function appear to be restricted to Cyanobacteria. Some members are annotated as membrane proteins however this cannot be confirmed.	4.92771e-38
NZ_CP046703.1|WP_114084271.1|2345143_2346634_-|BamA/TamA-family-outer-membrane-protein	gnl|CDD|227116	COG4775, COG4775, Outer membrane protein/protective antigen OMA87 [Cell envelope biogenesis, outer membrane].	1.16023e-75
NZ_CP046703.1|WP_114084274.1|2341605_2342022_-|fatty-acid-oxidation-protein-subunit-alpha	gnl|CDD|370136	pfam08814, XisH, XisH protein. The fdxN element, along with two other DNA elements, is excised from the chromosome during heterocyst differentiation in cyanobacteria. The xisH as well as the xisF and xisI genes are required.	2.83034e-80
NZ_CP046703.1|WP_114084280.1|2335882_2336500_-|FMN-dependent-NADH-azoreductase	gnl|CDD|224103	COG1182, AcpD, Acyl carrier protein phosphodiesterase [Lipid metabolism].	8.48828e-80
NZ_CP046703.1|WP_114084265.1|2355089_2356229_+|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.35928e-69
NZ_CP046703.1|WP_114084270.1|2347088_2347556_+|DUF4870-domain-containing-protein	gnl|CDD|225833	COG3296, COG3296, Uncharacterized protein conserved in bacteria [Function unknown].	1.72714e-29
NZ_CP046703.1|WP_114084276.1|2339896_2340376_+|pentapeptide-repeat-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	5.81616e-17
NZ_CP046703.1|WP_114084393.1|2349795_2350041_+|HNH-endonuclease	gnl|CDD|372995	pfam14279, HNH_5, HNH endonuclease. This domain is related to other HNH domain families such as pfam01844. Suggesting that these proteins have a nucleic acid cleaving function.	1.84196e-22
NZ_CP046703.1|WP_012412521.1|2356396_2357827_-|NADP-dependent-phosphogluconate-dehydrogenase	gnl|CDD|236453	PRK09287, PRK09287, NADP-dependent phosphogluconate dehydrogenase.	0
NZ_CP046703.1|WP_114084272.1|2343955_2344978_-|isopenicillin-N-synthase-family-oxygenase	gnl|CDD|226022	COG3491, PcbC, Isopenicillin N synthase and related dioxygenases [General function prediction only].	1.59658e-112

Protein sequences

>NZ_CP046703.1|WP_114084273.1|2342039_2342588_-|shikimate-kinase
MGSLLQGVNLYLIGMMGVGKTTVGPLLAKHLGYGFLDLDGVIAKATDKSINQLFAEEGEAGFRQIESDVLSQVCAFTKLTIATGGGIVLRRENWGYLHHGLIVWLDVPFDLIYSRLAEDTTRPLLQDADLKGKLRSLLEQRTPLYSQADLHISVQEGDTPEDIAKRILEAIPGVLKKTVSHE
>NZ_CP046703.1|WP_114084274.1|2341605_2342022_-|fatty-acid-oxidation-protein-subunit-alpha
MSAKDIFHESVKKALQKEQWRITSDPLKFKFGEVNFQIDLGVEKIIAAEKGNEKIAIEIKSFLNPSAITDFYSALGQFLSYRLALAGYEPERVLYLAVPLDTYKTFFQLEFTQTAIKQYQVLLIVYNPVNEVIVEWIN
>NZ_CP046703.1|WP_114084275.1|2341282_2341618_-|XisI-protein
MDKLAKYQEYVKTLLTKYASDDVSDNDVEVQLILDTERNHYQWMNIGWQGFNRIYRCVIHFDIKDGKIWLQQNLTDRNPAEELVMMGVPREDIVLGLQAPYKRQYTDYGVA
>NZ_CP046703.1|WP_114084394.1|2340559_2341183_+|Uma2-family-endonuclease
MTTLLIQTESTPITVNFPSLVQMTNEQFYEFCQVNEDLRIERTANGEVIIMPPAFSDTGNRNFNIAAQLGFWTEKDGTGIGFDSSTGFTLPNGAMRSPDASWIELERWNALTEAQKASFAPICPDFVIELRSSSVGVARRRHRLIKLQEKMQEYIDNGASLGWLIERQNRKVYIYRPNREIEILENPEAVSGNPELPGFILRMTKIW
>NZ_CP046703.1|WP_114084276.1|2339896_2340376_+|pentapeptide-repeat-containing-protein
MDEAITRAEERRELDRHFDTGDIEFLNRFFTPNTSTEELLKRIAAGEKEFADICLDDPNLSGINFAGANLTGAKLLGVNLSGANLEGANLSYAFLDGANLSGANLEGAKVAEASVVGANLENANLRGTIGSFGQAHRAFYHNTIMPYGNICTEPYWEEG
>NZ_CP046703.1|WP_114084277.1|2338872_2339769_-|acetylglutamate-kinase
MTDNDSEYIRQTEATRVRVLSEALPYIQQFAGRTVVVKYGGAAMKDSTLKDKVIRDIVFLSCVGLRPIVVHGGGPEINSWLDKLGIEPQFKNGLRVTDAATMDVVEMVLVGRVNKEIVALINQAGGLAVGLCGKDGNLFTARPQGQEDIGFVGEVSNVNIKILDTLASNGYIPVVSSVAADETGQAYNINADTVAGEIAAALGAEKLILLTDTSGILKDYKDQSTLIPKVDIREARELIVNGIVTGGMIPKVNCCVRSLAQGVRAAHIIDGRIPHALLLEIFTDVGIGTMILGSQFTS
>NZ_CP046703.1|WP_114084278.1|2338052_2338595_-|hypothetical-protein
MSAESLEIAKTFYQTGKIAFENGRYREAVENLEKASALLARNSRFGGEVEICLVTAYEAAGRTDEAIALCERLKRHPYIEISKQARQMVYILKAPKLKRPSEWMTQIPDLGTVQENELKISVAAKPTKSSVPQKPKPTEPEFVDLSQVNTRDNRFIWVALIAIGLTISYLVWLNFSGTPG
>NZ_CP046703.1|WP_114084279.1|2337141_2338026_-|DUF3153-domain-containing-protein
MVSTSSIFGKILLWLIRPFSFVLTLNGRNRMNRVFPMRNPILWLVLLTSLLLTGCVKYDVGLNFDNSNSGEFVQHIKLGERLTSFSGDSVYEWLNSIERRARQLEGKTQRVSQEEIIVTIPFSSGSELQEKFNEFFNSRTNQSSDAVQSKSDSELPKIESNVLLEQNYFLLLVRNRLIYDLDLRSLALIASKGNVLANAGSILDLEFSLKTPWGAKNIQLTETAIEPEKNGNQLVWKLQPGQLNHIEAVFWLPSPLGIGALLIILFVWGGLYLRYNFMPDPRTQLLPKAAATQE
>NZ_CP046703.1|WP_114084280.1|2335882_2336500_-|FMN-dependent-NADH-azoreductase
MVNILHIDSSPRAERSHSRELSKEFVSAWRAAHPEDAIAYRDLGHHPVPHVNEAWIAAAFSPPETHTPELAEAIRVSDELVDEFLAADRYVFGVPMYNFNIPSTFKAYIDQIVRINRTVSLDAQGFKGLVEGKKAVVITARGGDFSPTSPAVAYDFQEPYLRTIFGFIGITDIQFINANSLNEGDARTQSLAEARAAIQDAIAQW
>NZ_CP046703.1|WP_159402487.1|2335690_2335834_+|hypothetical-protein
MALGKLSGCHPEEEAGGWEQGAGGREQGAGEAGGAGEAGEEKLFIDS
>NZ_CP046703.1|WP_114084272.1|2343955_2344978_-|isopenicillin-N-synthase-family-oxygenase
MKNLQVVEKEFSSLPIIDISALLSGTGNLYSVASQIRQACRESGFFYIIGHGVDENLQQRLEELSRHFFAQDLETKLKIRMPLAGIAWRGYFPVGGELTSGKPDLKEGIYFGAELPDEHPLVQAGTPMHGSNLFPANIPQFAETVLEYMEAMTNLGHILMTGIALSLGLEESYFADRYTSDPLVLFRIFNYPPNLSPSDGNPIWGVGEHTDYGVLTILKQDDSGGLQVKSKSGWVAAPPIPGSFVCNIGDMLDKMTGGFYRSTPHRVQNQSPNHRLSFPFFFDPNFDVEVKPIELDNIVANDNISDRWDNANIHDFRGTYGDYVLNKVSKVFPELRRTVL
>NZ_CP046703.1|WP_114084271.1|2345143_2346634_-|BamA/TamA-family-outer-membrane-protein
MRVQITVVAIAVMLVGGKNPEALADLQPSTQDGASGIVTPEATIQIEGGYAKYGDYIGVSLGDSQTLEISQKIVKNIQIRFINDKGLPIKGRTQKDFIIGLLRLKPGQLFREDLLQADLQRLRRLESFNQVNVYSKEDGSSVNILYAIKERSFPSLILGGGNNDDVGLYGRVGYKDENVSGLNDKLDTVLQFSTKDVQFDGQFTSRYRSEEPNRLGYSVRGFRNRNTSGTFNEDIRLANGDKVREGRFGGSVALLRAFDEWDTSVALNYTRISLRDGEYNVVQVDRLGSPLSVSGTGIDDLFTVSFAVSRDQRDRRDNPTQGSILTFSTEQAIPIGLGNISSNRLRGDYIQYFPVSWIGNGKPTDNPEMLAINLQIGTTIGDFPPADAFNIGGIDSVRGYGYGKVASGRSYGLASVEYRFPIFQSIGGVVFTDFASDFGSSETVLGEPGVLRDKPGSGFGYGLGLRLNSPFGLIRGDLGISDQGEVRFEVTTGQRF
>NZ_CP046703.1|WP_114084270.1|2347088_2347556_+|DUF4870-domain-containing-protein
MRQKPKQQMRIWAMLCHLSALLGWILLFFLVFIGIPLYLPLNLLAPLIIWHFKKSQYPWIDFQGKESLNFQFSLTLYTLIVIAISLVFLLTSFVLVVINNGSSKEIKNILDGLLIVLMSLILFKFILQSFVVTFASVKAYKGEYYRYPFTIRVLR
>NZ_CP046703.1|WP_114084269.1|2347623_2348538_+|hypothetical-protein
MYDTSKNTIGFILLSHRKPLQIYRLISKLNSLFDYPRIVCHHDFSKCDLSIKNLTKNILLLRPHIETEWAGFSLVKATLKALRLMYETPDSPDWFVLLSESDYPIKTAKQILDDLASSPYDAYIRHEQIKYETYKYDVRPSILWQKNSYERYCTKSFSFHYSKKYSTQVNLEIRLEHPLLTKYFLPFSKKLLCFSGSQWFCANRKAAEYIIDFHSKGNALTLHYSKLRYADESYFQTILANASHLKLQNDNWRYIDWSGGSATHPKTLLMEDIPNLITSSAHFARKFDIDIDSTILDELDIITF
>NZ_CP046703.1|WP_114084268.1|2348690_2349788_+|Gfo/Idh/MocA-family-oxidoreductase
MVKIAIAGTGFGQKVHIPGFQAHPQTEVVAVYHRDINKAKAIAESHNIPHASDSLADIVALPEVQAVSISTPPFLHYEMAKTVLQAGKHLLLEKPTTLNAVEAKELYQLAKAKGVIATVDFEFRFVPAWQLFAELLSEDYVGELRLIKIDWLGSSRADTSRPWNWYSDKDKGGGALGSLGSHAFDYIHWLFGPVRRLNAHLSTAIPTRVDPVSGESKPVNTDDNCILTLELANGTPCQVSISAVVHAPRTHWIEVYGDRGTLIVGSENQKDYIHGFRVWGSQPGKPLTEIEIPNRLIFPKNYADGRISAFIRVVDQWVQGIERNQEITPSLREGIYSQLLMDLSHESHTKASWVDVPSLERFLSN
>NZ_CP046703.1|WP_114084393.1|2349795_2350041_+|HNH-endonuclease
MSKTPRIRIPPEVKKYVFERDKYQCQSCGKTTTETHLSIDHIIPLARGGQNDISNLQTLCLTCNQQKTDNIDPRFRRYFEL
>NZ_CP046703.1|WP_114084266.1|2350572_2353290_-|DUF3536-domain-containing-protein
MTSAAEMPASSGSTLTLHSDPNNTKETDPLRKANGVYVTVHGHFYQPPRENPYLDAIERQPSAAPFHDWNERIHWECYRPNAFARVLNDQGEVVGIVNNYEYFSFNIGPTLMSWLERYDVEVYQRILEADAKSSQRLHGHGNAIAQVYNHIIMPLANERDKYTQIRWGKEDFRSRFGRDPEGMWLAETAVDYATLEALVAEGIRFIVLAPSQALRCRPLPTPDHPHPEWIEVGGSQIDSTRPYRCYLKPTLDTSSSPLSAIATSPNDGSTEELPYIDIFFYDGPISRDMGFSDVVYNSSHFAGRIGSAVRGDHRLAQLISVATDGETFGHHKKGTEKTLAYAFTKEFPQQGWTVTNFAHYLSLNSPGWEVELKSVTAWSCAHGVGRWEDDCGCGGEGGVWHQKWRRPLRDALNWLRDQLTEVYEEHGRQLFRDPWQTRDEYIQVMRDRSATNVNRFLARHQTHKLTAAEQVDALRLLEMQRHALLMFTSCGWFFEEISRPEGTQILRYAARALELAGEVAGVQLEKGFVKRLGLAPSNVDEFKHGAEIYRQLVLTAQLGFKQVASHYAITSLFTNQKPAQTHNSLPRKDVADKQSQRYHKKVYCYAANELDYQLQRMGSLTLAVGNLKLVSEITWESEHLVFAVLHLGGWDFHCCIQQFTGRRDYSQLKEKLFGALKQASAAHTILAMTQLFGEEAFSLQNLFAEERHRIMRLLSQETLTRLGQLYTQAYRDNYGVLMAFHRDEIAVPQELQVAADIALGHRCLMTLRSLEQDIADPQKSWSHILELEAIATEAKHLRCRLNIPDGKQMLEQLIARSLWQLLHDANGSFNADIQLLERLIDVGDQLNIDISLQRSQELYFSCLHSQIAPVCITSLGNEGDNQCLQLLKLGKKLAVDVSAISNQLG
>NZ_CP046703.1|WP_114084392.1|2353817_2354909_+|calcium/proton-exchanger
MSTKNIILFVLLLFIPVSVAAHFLEWGELIVFITAGLAILPLAAWMGTATEEIAVVVGPSLGGLLNATFGNATELIIALVALNAGLIDVVKASITGSIISNLLLVMGFSMLLGGLRYKEQTFQPIVARVNAASMNLAVIAILMPTAMNYTSQGISEETVQNLSIAVAVVLILVYALTLLFSMKTHSYLYDVGVAETEAEEIPHAKPNMMLWVGVLLVCTLLVALESEMLVDSLEVATSQLGLTALFTGVILVPIVGNAAEHATAVTVAMKDKMDLSLSVAVGSSMQIALFVAPVLVIAGRILGKPMDLDFKPFELVAVVVSVLIANSISSDGKSNWLEGTLLLAAYTVLGFAFYFHPVMEGMG
>NZ_CP046703.1|WP_114084265.1|2355089_2356229_+|serine/threonine-protein-kinase
MSYCLNPHCPKPENPHDVKFCRTCGSKLLLKERYRAIKPIGQGGFGRTFLAVDEDKPSKPRCVIKQFYPQSQGTNTLAKAVELFNQEAVQLDELGKHPQIPELLAYFTQEDRQYLVQEFIDGHNLAQELAHRGAFNETQIRQLLNDLLSVLQFCHARHVIHRDIKPENIILRSGDSKLVLVDFGAAKSATGNALNQTGTSIGSPEYVAPEQMRGRAVFASDIYSLGATCINLLTQRSPFDSYDTNNDTWVWQKYLKTPVSNHLSHILNKMLESIPVRRYQTVDEVLKDLNPHSQVAATPAIKPKPIPQSPPNSPPAFVSPSPSQIDLELEEMKTQFLGGNKPQANKIQPPISTSQPTSKNEIDQELEELKAKYLGNNNP
>NZ_CP046703.1|WP_012412521.1|2356396_2357827_-|NADP-dependent-phosphogluconate-dehydrogenase
MTLQSFGVIGLAVMGENIALNVERNGFPIAVYNRSREKTDAFMAQRATGRNVKAAFTLEEFVALLERPRKILVMVQAGKPVDAVIAQLKPLLEEGDIIIDGGNSWFEDTERRTQELEPAGLRYLGMGVSGGEEGALNGPSLMPGGTTSSYEFLSPIFNKIAAQVDDGPCVTYIGPGGSGHYVKMVHNGIEYGDMQLIAEAYDLLKNVAGLNPSQLHDVFAEWNTTDELDSFLIEITKNIFPYIDPETNKPLVDLIVDAAGQKGTGRWTVQTALELGVAIPTITAAVNARIISSIKDERVAASKVLTGPSGKYDGQTKDFINKVRDALYCSKICSYAQGMALLSTASKTYNWNLDLGEMARIWKGGCIIRARFLNKIKKAFSENPALPNLLLAPEFKQTILDRQTAWREVIATAATVGIPVPAFSASLDYFDSYRRDRLPQNLTQAQRDYFGAHTYLRLDKPGSFHTEWVPIAEAGK

Crispr_ID: NZ_CP046703_7

• CRISPR_ID: NZ_CP046703_7
• CRISPR_location: 2456944-2457067
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP046703_7

Consensus_repeat	Method
TTCTGTTCATCAACAAACCCATGCGTTTCATCAACAAAAT	CRISPRCasFinder

spacers of NZ_CP046703_7

>7.1|2456984|44|NZ_CP046703|CRISPRCasFinder
CATGCGTTTCATCAACAAAATCGTTCTGTTCATCAACAAACCTA

CRISPR arrays and Neighbor proteins around NZ_CP046703_7

CRISPR arrays

The CRISPR arrays of NZ_CP046703_7

>merge|NZ_CP046703|7|2456944-2457067|CRISPRCasFinder
CCCTAATCATCAACATAATCATTCTGTTCATCAACAAACCCATGCGTTTCATCAACAAAATCGTTCTGTTCATCAACAAACCTATGCGTTTCATCAACAAAATTGTTCTGTTCATCAACAAACT

>NZ_CP046703|7|7|2456944-2457067|CRISPRCasFinder
CCCTAATCATCAACATAATCATTCTGTTCATCAACAAACC	CATGCGTTTCATCAACAAAATCGTTCTGTTCATCAACAAACCTA
TGCGTTTCATCAACAAAATTGTTCTGTTCATCAACAAACT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046703.1|WP_114084086.1|2467114_2468752_-|CTP-synthase	unknown	unknown	gnl|CDD|235437
NZ_CP046703.1|WP_114084096.1|2449409_2449844_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114084095.1|2450025_2454237_-|DEAD/DEAH-box-helicase	unknown	unknown	gnl|CDD|223627
NZ_CP046703.1|WP_114084091.1|2457743_2460404_-|GAF-domain-containing-protein	unknown	unknown	gnl|CDD|223715
NZ_CP046703.1|WP_114084089.1|2463517_2465110_+|FAD-dependent-monooxygenase	unknown	unknown	gnl|CDD|223727
NZ_CP046703.1|WP_114084084.1|2470866_2471292_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114081258.1|2445867_2446167_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114084083.1|2471407_2471983_-|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|224276
NZ_CP046703.1|WP_114084087.1|2466567_2466990_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_159402489.1|2444805_2444961_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_159402490.1|2446304_2449310_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|315987
NZ_CP046703.1|WP_114081256.1|2444334_2444685_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_159402491.1|2456417_2456576_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114084088.1|2465338_2466382_+|agmatinase-family-protein	unknown	unknown	gnl|CDD|212539
NZ_CP046703.1|WP_114081257.1|2445377_2445764_+|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|350220
NZ_CP046703.1|WP_159402492.1|2460670_2463079_-|TIR-domain-containing-protein	unknown	unknown	gnl|CDD|379765
NZ_CP046703.1|WP_114084092.1|2457256_2457685_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114084094.1|2454364_2456131_-|SWIM-zinc-finger-domain-containing-protein	unknown	unknown	gnl|CDD|227059
NZ_CP046703.1|WP_114084085.1|2468836_2470612_+|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl|CDD|119407
NZ_CP046703.1|WP_069074142.1|2445126_2445375_+|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	unknown	unknown	gnl|CDD|226603

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046703.1|WP_114084086.1|2467114_2468752_-|CTP-synthase	gnl|CDD|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NZ_CP046703.1|WP_114084095.1|2450025_2454237_-|DEAD/DEAH-box-helicase	gnl|CDD|223627	COG0553, HepA, Superfamily II DNA/RNA helicases, SNF2 family [Transcription / DNA replication, recombination, and repair].	8.151e-113
NZ_CP046703.1|WP_114084094.1|2454364_2456131_-|SWIM-zinc-finger-domain-containing-protein	gnl|CDD|227059	COG4715, COG4715, Uncharacterized conserved protein [Function unknown].	6.75754e-99
NZ_CP046703.1|WP_114084083.1|2471407_2471983_-|pentapeptide-repeat-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	1.9592e-14
NZ_CP046703.1|WP_114084091.1|2457743_2460404_-|GAF-domain-containing-protein	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	3.38508e-52
NZ_CP046703.1|WP_159402490.1|2446304_2449310_-|tetratricopeptide-repeat-protein	gnl|CDD|315987	pfam13424, TPR_12, Tetratricopeptide repeat.	1.65953e-15
NZ_CP046703.1|WP_069074142.1|2445126_2445375_+|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	gnl|CDD|226603	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning].	6.24985e-17
NZ_CP046703.1|WP_114084088.1|2465338_2466382_+|agmatinase-family-protein	gnl|CDD|212539	cd11593, Agmatinase-like_2, Agmatinase and related proteins. This family includes known and predicted bacterial and archaeal agmatinase (agmatine ureohydrolase; AUH; SpeB; EC=3.5.3.11), a binuclear manganese metalloenzyme that belongs to the ureohydrolase superfamily. It is a key enzyme in the synthesis of polyamine putrescine; it catalyzes hydrolysis of agmatine to yield urea and putrescine, the precursor for biosynthesis of higher polyamines, spermidine, and spermine. As compared to E. coli where two paths to putrescine exist, via decarboxylation of an amino acid, ornithine or arginine, a single path is found in Bacillus subtilis, where polyamine synthesis starts with agmatine; the speE and speB encode spermidine synthase and agmatinase, respectively. The level of agmatinase synthesis is very low, allowing strict control on the synthesis of putrescine and therefore, of all polyamines, consistent with polyamine levels in the cell. This subfamily belongs to the ureohydrolase superfamily, which includes arginase, agmatinase, proclavaminate amidinohydrolase, and formiminoglutamase.	2.09034e-97
NZ_CP046703.1|WP_114081257.1|2445377_2445764_+|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|350220	cd09872, PIN_Sll0205-like, VapC-like PIN domain of Sll0205 protein and homologs. Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of the Synechocystis sp. (strain PCC 6803) Sll0205 protein and other uncharacterized homologs are included in this subfamily. They are similar to the PIN domains of the Mycobacterium tuberculosis VapC and Neisseria gonorrhoeae FitB toxins of the prokaryotic toxin/antitoxin operons, VapBC and FitAB, respectively, which are believed to be involved in growth inhibition by regulating translation. These toxins are nearly always co-expressed with an antitoxin, a cognate protein inhibitor, forming an inert protein complex. Disassociation of the protein complex activates the ribonuclease activity of the toxin by an, as yet undefined mechanism. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	8.38794e-62
NZ_CP046703.1|WP_114084089.1|2463517_2465110_+|FAD-dependent-monooxygenase	gnl|CDD|223727	COG0654, UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion].	1.11394e-39
NZ_CP046703.1|WP_114084085.1|2468836_2470612_+|N-acetylmuramoyl-L-alanine-amidase	gnl|CDD|119407	cd02696, MurNAc-LAA, N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino acids in certain cell wall glycopeptides. These proteins are Zn-dependent peptidases with highly conserved residues involved in cation co-ordination. MurNAc-LAA in this family is one of several peptidoglycan hydrolases (PGHs) found in bacterial and bacteriophage or prophage genomes that are involved in the degradation of the peptidoglycan. In Escherichia coli, there are five MurNAc-LAAs present: AmiA, AmiB, AmiC and AmiD that are periplasmic, and AmpD that is cytoplasmic. Three of these (AmiA, AmiB and AmiC) belong to this family, the other two (AmiD and AmpD) do not. E. coli AmiA, AmiB and AmiC play an important role in cleaving the septum to release daughter cells after cell division. In general, bacterial MurNAc-LAAs are members of the bacterial autolytic system and carry a signal peptide in their N-termini that allows their transport across the cytoplasmic membrane. However, the bacteriophage MurNAc-LAAs are endolysins since these phage-encoded enzymes break down bacterial peptidoglycan at the terminal stage of the phage reproduction cycle. As opposed to autolysins, almost all endolysins have no signal peptides and their translocation through the cytoplasmic membrane is thought to proceed with the help of phage-encoded holin proteins. The amidase catalytic module is fused to another functional module (cell wall binding module or CWBM) either at the N- or C-terminus, which is responsible for high affinity binding of the protein to the cell wall.	1.53056e-60
NZ_CP046703.1|WP_159402492.1|2460670_2463079_-|TIR-domain-containing-protein	gnl|CDD|379765	pfam16095, COR, C-terminal of Roc, COR, domain. The C-terminal of Roc domain, COR, along with Roc functions as the putative regulator of kinase activity. It functions as a proper GTP-binding protein with a low GTPase activity somehow stimulating the kinase activity.	1.07156e-82

Protein sequences

>NZ_CP046703.1|WP_159402491.1|2456417_2456576_+|hypothetical-protein
MSQIQQIISTVRPCKIDSATARDSVDLVVVIDTSPSVRNEAYNLSNAAFLFT
>NZ_CP046703.1|WP_114084094.1|2454364_2456131_-|SWIM-zinc-finger-domain-containing-protein
MSIPGISEAIIRHNSNASSYSRGEEYYRRGAIAELKKRGNLIQAEVEGGEITPYQVSIRFDAGGITSACCTCPYDYDGWCKHIVATLLSCSRQSEIIEERPTLEQLLNRLDLLQTQRLLQELVENRPEIIDDIDEFVSLIDLPKPKTKQPSTRQSKIDTSPFRSHVKRILRDGLKELEYGSEEDPFTDDLLAVIEKARELAENGDGNNAIAILETITETYAQEWDELLDYGGDSYSIAEPLDSAWTEAILCAEMSTGEIVDLQLMLESWQDEISADFSMSLEALRQGWDYEPLQQIMQGYDTAELWENERPSFADDLALIRLQILERQNRYTEYLNLALVEEMTLQYLTQLAALGRVEEAMSAAKILMERAEEGFALAKILREDGYLVEALEICQAGINLTGNCLYEFATWTSDLAQGLEDNATALTASIIAFKIRPSFRDYGKIQDYAGETWLTIKQDLLQTLRDQPNWGIKEAQVDIFLHEGLIDDAIRTVERDIYYASELVHRVMDAAVSHRPDWVIDNARRRAEPIMEQGKADRYDAAVNWLKKAKSAYLQLGQKTEWSAYRSQLEAAHGRKRKLMELFKQLNQ
>NZ_CP046703.1|WP_114084095.1|2450025_2454237_-|DEAD/DEAH-box-helicase
MINLATDTTKLQTQLADKYFKLHPSIQKIIQLFSLVYAPIDKNSFVSCLSKIDALDENNKPWVTKTLSFQIDKLLKAGLLIQESRQGAECHPLLTEIATRHAVQTGQFEILVTVVEEKLPIHTHWNRDYRIFSSLRQCIREIRIGIYRQDLSFINQQIEAYQKYSDSEEKIVIENIFEQIYNNPFDADWFNTLPQGLYESGISSILFNSALKLSASEDALMLLEEECSTPGKHCSDYLHLILTEQLLLQGCTQEAQESLERISNEYQNNAAIFRGWLSFLRGDNEQAIKYYKDALKAIKKATGKRQIYFNTIGGLFFILVLLKDGSAQSLKEAEEYSSLMSRQSDHWLRFTYGRLKMVLQVHQGDITQKQFVVSGHISSVEEENSLQTLFCSLCLYWMDAESAKKRLPNLLEPLYRRSLTSGYHWLAMETAELLSRLKPSSNYKQLAEALREDSNIQTIVDLIRPQEAWEMCLNALANLQKEPQTPGKPESELRLAWFITFYPSRCVLQPKEQKVNAKGEWSKGRPIALKRLSSALSEFDYITPQDMRVCSCIEAYSDGYYGKVDYTFGEKAISALIGHPLVFWEDTPTIRVEIVKGEPELLVKKGKQDRLTLEFSPKLPESQNILHIKETPTRIKVIEITAEHRRIAEIIGIDNKLNVPAIAEKQVLAAINAVSGIVTVHSDIGGGSEGAEEVPAQTLPHIHLLPANAGLKISLLSRPFAQGGPYYRPGTGGETVIAEIDGKRLQTRRNLSEEKQLAKDAIAACATLTRTEEQDGEWIIDEPEDCLELLLELQAQGNNVVIEWPQGEKLRVSHNADLKDFNLSIQRQQDWFAATGELKLNNDLVLDMQQLLELLEKTPSRFIPLGDGQFLALTQAFRKRLDELRMFSEKHSKGIRFHPLATLGLEDFVDEVGKVKADKHWKTHIQRLHEVQNLQPELPSTLQAELRDYQMEGFCWLARLAHWGVGACLADQMGLGKTLQALAVILRNAHEGPTLIIAPTSVCMNWVSEAQKFAPTLNIIQFSGANRQKLLDGLQPLDMLVCSYGLLQQEEVAQMLAQIQWQTIVLDEAQAIKNMTTKRSQAAMNLKSNFKLLTTGTPIENHLGELWNLFRFINPGLLGSFESFNQRFATPIEKYQDKLARNKLKKLIQPFLLRRTKNQVLEELPSRTEILLHVELSREEKAFYEALRRQAISKLTESDAEAGKKHLQVLAEIMKLRRACCNPSLVMPGTELPSSKLQLFGEVLGELLENRHKALVFSQFVDHLHIIRDYLEQQGINYQYLDGSTSVAERKKRVDAFQAGSGDVFLISLKAGGTGLNLTAADYVIHTDPWWNPAVEDQASDRAHRIGQQRPVTIYRLVAKDTIEEKIVQLHHQKRDLADSLLEGTEMSGKISTEALLQLISES
>NZ_CP046703.1|WP_114084096.1|2449409_2449844_-|hypothetical-protein
MILETAAIAIGSVIATKALEKTTEKVTETLLDKAGKFLVTLKKQSPHTVAAIEKAPEQAIDYGKALLEVESAAKANPEVAEAIKELAEAAKTEPNPQFIQSIQEFADTLKSQPQQPNSINYKNLANEIKNVFQGNTFNAPVTFN
>NZ_CP046703.1|WP_159402490.1|2446304_2449310_-|tetratricopeptide-repeat-protein
MLHEDLQHKDYVAIAGMGGVGKTELATQYARRYQQDYGGITWFNDRETNLAAEVLEFFRLQFDLEIPQELGERFLSLEEQVAWCWSRYPNSELPILIVFDDVTDLDNLRQVVPKDNRFQVLITTRLRHLDPNFIQEISLDVLSPQKEPGKALELLKRLLGEKDKRVENQPQAATNICECLEYLPLGIELVGAYLVRDPDISLDMMFGRLQERKLAEEALQDRKTIHPTQLGVKAAFALTWEELDPLAQQLGRFLSLFSPALILWDLVIWVATVGGEGENQEERQLTWSEDELNQAKKQLYGRNLLQLVEEREGCYKIHALVRWFLQEELANSGETKSVLETIFATAMITLAQSLPNSPTSKQIESIRDIVPHLEDLSKRIIAEIKEAKEVQIISLASVPNDELIWIFVGIGRFYNGQGLYQLAEPWSRECVNVFQSLFAGDHLDVATSLNNLAGLYNSQGRYSEAKPLYIEALAMRKRLFAGDHSDVATSLNNLAGLYNSQGRYSEAEPLYVEALAMRKRLFACDHPDMATILNNLAFLYYSQGRYSDTEPLYVEALAMRKRLFAGDHPDVAASLNNLALLYYSQGRYSKAEPLYVEVLAMRKRLFAGDHPDVAASLNNLAGLYNSQGCYSEAEPLYVEALAMRKRLFAGDHPDMATTLNNLAFLYYSQGRYSEAEPLYVEALAMRKRLFAGDHPDMAASLNNLALLYYSQGRYSEAEPLYVEALAMTKRLFAGDHPDVAASLNNLAALYNSQGRYSEAESLYVEALAMRKRLFAGDHPDVAASLNNLALLYNSQERYSEAEPLYVETLAMRKRLFAGDHPDMATTLNNLAFLYYSQGRYSEAEPLYVEALAMTKRLFAGDHPDVAASLNNLAALYKRQGRYSEAEPLYVEALAMTKRLFAGDHPDMAASLNNLAFLYYSQERYSKAEPLYVEALAMCQRVLGVNHPTTTTIRENLAILQRQSTPRAIWLRRLGQFVQILLAILILPFYLLWRLAKKLIRN
>NZ_CP046703.1|WP_114081258.1|2445867_2446167_-|hypothetical-protein
MNFPPQLQQKIEKWASSQGISTEQFVLQAIAEKINTLSQQVTEEHTQQNSEIANVPPLNQPNIYRKQGILVVEAELPENFDVNAFIDELREERIQDQIA
>NZ_CP046703.1|WP_114081257.1|2445377_2445764_+|type-II-toxin-antitoxin-system-VapC-family-toxin
MRALLDTHVFIWWVTDDPQLSSTSRSIIADSGNILFLSVASVWEIVIKTKSGKLTLPEPVEEYIPNRLALNRFESLDIQMTHTLQVANLPNIHRDPFDRILIAQSQVENLPIVTIDQKIAQYSVEIIW
>NZ_CP046703.1|WP_069074142.1|2445126_2445375_+|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin
MSITVNVSEVTAKFSELLSQVLLGEEVVIAQKGIPVARLVALTDTASPRIPGLDKGKVIIAPDFDEPLPEDILNDFDSSNLV
>NZ_CP046703.1|WP_159402489.1|2444805_2444961_-|hypothetical-protein
MIALVERLVYFNERNCDRWETKLDNHTISKNSNVIAWLIFCLFILPDIEQK
>NZ_CP046703.1|WP_114081256.1|2444334_2444685_-|hypothetical-protein
MNAKIIALLGITTAFASLGSQVYAQSPASSLNSGQYRLTGDSLVGIDNRTAQDDFGKFFEQTNPSTISNNNRTDKTPVKIRFNETLSQPDTSVFLTPAQSGNDNDGLQVQLDLGRE
>NZ_CP046703.1|WP_114084092.1|2457256_2457685_+|hypothetical-protein
MPAQKRTYRVLEKAELRVAGLKAIDPSMDFGDARNLQNMTQLIEQYRSKIDAYNTALAVIDSSRTEMEELDKALSDITEKMLIGVAFKYGKDSREYEMAGAVRKSDRIRKSRATRLRATPKELASENAKTAYLNGLNGAIAE
>NZ_CP046703.1|WP_114084091.1|2457743_2460404_-|GAF-domain-containing-protein
MNKNIGQNGVFPLFKGVPLRRILVALFVLQILLAVGLTAYLSIRNGQMAVNEVASELRYEVANRVEQNLQAYLSTPRQVLRGNQNVIDIGLLKMENLATWESYLIKQLEIFPDAIALTASNEQQEHLAVEKLNDRQYLLRKADKSTGYDLYTYKIDSQNQRTQLPEVIKNYDARSRPNYQAAVTAKKFSFSQIFTSITEPTLLISASQPIYNSQGELLGVNSTLTHVSQIGDLLQNIKVGKSGQVFIIERSGLLVASSTTEEPFRLQNGKPIRLAASQSGNAFTQASAKYLETKFSNFDQIKSLQQLDFSFDGKRQFLEIRPLQGEPNANWLIVVAVPEADFMGQIDRNTQTTIFLCLGALGLATLLGIITARWITQPILYFSTATKDLADFTKGEDSVVIVQGIKEVEILGESFNEMMQHLRKTFTAQITKNEELELQVKQRTQELQQEIQKSINSQQKLEHHNRALAELANHRAISEGNLETAFKVITEKAANALEVERVSVWLFNSDDDDRLRQRTKLQCISLYERSNQKHSAGLERDRADYPIYFKSLTSARIIAVTDTRTDLRIQELWDELLETKNIVSLINTSIWVGGEVVGTVLYEQIDIPRTWEVSEQNFVSSIAEFVALTLEVCDRKSAESALREAKEAAEVANRAKKTFLVNMSHELRTPLSSILEIAEALQNEVYGTVTEEQRQFLNTLESSGKNLLELINQILELTDIESSKIELQLAATSIPELCDSSLSFVKNLALQKNIQLSVQIPEELEPIQVDERRIRQVFINLLSNAIKFTHDGGKVWIEVQPNSTNEYIFFSVVDTGIGMLSDDLFRLFQPFIQVENASTRRSAGTGLGLVMVQKIVELHGGTVHAESQLGKGSRFTVKLPWKKVGE
>NZ_CP046703.1|WP_159402492.1|2460670_2463079_-|TIR-domain-containing-protein
MTNEELLQIIEQAVRDNVTKLDLSDKRLTTLPPEIGQLTNLQTLYLYGNQLSSLPPEIGQLTNLQSLDLSYNQLSSLPPEIGQLTNLQSLELRNDRLSSLPPEIGQLTNLQTLDLSYNRLSSLPPEIGQLTNLQSLDLNSNRLESPPPEIITKGFKAILDFCRQQLEQKTDRLYEAKLIIVGEGGAGKTTLAKKIQDNKYTLQQDENTTEGIDVIQCKFLLDNNREFQVNIWDFGGQEIYHATHQFFLTKRSLYALVADTRKEDTDFYYWLNAVELLSGNSPLLIVKNEKQERKREINERELRREFTNFKETLTTNLATDRGLSEILNKIKHYITNLPHVGIELPKTWVKVREALEGDSREYISLEEYMNICQKHGFTKQENKLQLSGYLHDLGVCLHFQDDDLLIKTVILKPTWGTDAVYKVLDNSQVIEKLGQFDRNDLANIWHEDKYADMRPELLRLMMKFKLSYEIPSRPGTYIAPQLLSVNQPDFNWDESNNLILRYKYDFMPKGILTRFIVEMHSDIEQQTLVWKTGVVLAKYESRAEVIEYYNQREIQVRVAGKRKKELLVVINNELEKIHKSYERLQYQTLVPCNCKSCNDSQSPHFYNRDVLYKFRDNNRYQIQCQDSGDMVDVRRLIDDVLPTQPNLEIPMSEPVIRNQVFISYSHQDQEWLTKLQKHLKPMIRNQKLLVWDDTKIQPGAKWREEIKNALAVAKVAVLLVSPDFLASDFIADNELPPLLDAAEAEGLTIIWIPLSSSGYDETEIEKYQSAHPPNQPLDRLDSGQQNEAWVAICKKIKAAVLG
>NZ_CP046703.1|WP_114084089.1|2463517_2465110_+|FAD-dependent-monooxygenase
MPETQSSPHTHTNTSTKDDTLPASVISSSTSQEIYDVVVIGAGPIGLATAIGLRKRGIENVLVIDQTRAFRQVGQTLDLLPNGLQALRHLDPNAYEEVKKTGLGLLSPKQSNDQETVEPTQKQQPPKASPQWIYKNLQGEIIRSTSLSFDDWFKDYGDGRVSISWYNLQTTLRQLLPPDLVKANHRCINVVNEPEKGCVRIDCVGDTAIETNPYAYWIDGQKDNDPQPQNSEIVPQELATKSIRAKLIVAADGINSTVRKLLYTDTQHHDFASPEYSGFAAIFCMEIAEVPKELLTKLEEDFFQDSPLVTITNDEITGNSVCINNIRIILFRRPTGVLGYIIHLALPLDSLQGKSESSLIDLALQELEKAGFPDALKQLVRLSPPAKMQQRPYYVHRASILDSVQVSNPTDLNPEANPAKISPAWSVGRVVLVGDAAHGMPPFMAQGANQGLEDALIVTTLIAKIAEENNWDNLQAIAKAFEKYECLRRPLMAYVQEATLKRSPHSSDKEWHDYSQQMYCRNFDQVIEAL
>NZ_CP046703.1|WP_114084088.1|2465338_2466382_+|agmatinase-family-protein
MSNQLQDYNPSGVGEINGNLLGLPCDYESANLIVFGVPWEVTVSYGAGTANGPQRILDASTQLDLFDFDNPNGWKQGIFMVEIPQDILEKNTYYRALAAKIIERLAQGKELSDTPDLTSVLTEINQAGEQVNQWLFENCQEAINKGKGVAVIGGDHSSPLGYFQALAANYANYGILHIDAHADLRDAYEGFEFSHASIMFNAMKIPQISKLVQVGLRDISHDEVQMIDQSDRRIIAYYDPAIKQKLYSGTTWLDLCREIISHLPEFVYISFDVDGLDPKLCPSTGTPVPGGLELEQTFFLFRELVKSGRKIIGFDICEVGDAEWDGNVGARVVYKLANLMDLSKQNS
>NZ_CP046703.1|WP_114084087.1|2466567_2466990_-|hypothetical-protein
MAYWVKILYERREYVVNFERVHAFCYEVNGRVTFWLPDSAIPIVINPQSNLEDYQKILDYLECVTSLELDHAHWVKILYEKNEYVINLNCISSFCHEPNGRITFWLPDGTIPIIINPVSNPESYQKVVQYVHKATGYSLS
>NZ_CP046703.1|WP_114084086.1|2467114_2468752_-|CTP-synthase
MTKFIFVTGGVVSSIGKGIVAASLGRLLKSRGYSVSILKLDPYINIDPGTMSPFQHGEVFVTQDGAETDLDLGHYERFTDTSMSRLNCVTTGSIYQAVINKERRGDYNGGTVQVIPHITNEIKERILRVAKSTNPSVVITEIGGTVGDIESLPFLEAIRQFRKEVGRQHVLYMHVTLVPWIASAGEMKTKPTQHSVKELRSIGIQPDILVCRSDRPLPKGLKQKLSGFCDVPEECVITSQDAKSIYEVPLNLEREGMAEQVLSLLQMEQRQPDLTQWQTLVQRLHTPKHELEIAIVGKYVQLSDAYLSVVEALNHAAISTYGKLRLRWVNSEDLENESVETHLGGVDGVVVPGGFGVRGVDGKIAAIKYARDRQIPFLGLCLGMQCSVIEWARHIGGLTDANSAEFDAHTTNPVINLLPGQQEVVDLGGTMRLGLYPCRVLPDTLAFKLYQEDVIYERHRHRYEFNNAYRDLLLKSGYVISGTSPDGQLVEIVELPKHPFFLACQFHPEFQSRPSSPHPLFKGFIQAAIALSLSTSTTPTPLEVS
>NZ_CP046703.1|WP_114084085.1|2468836_2470612_+|N-acetylmuramoyl-L-alanine-amidase
MKNLLGLVILGCILTSSVALAEPSLIVVFPKTNYQTSSQKIFFLGTAPPDGEVLINSKPINRSKAGHFSPSFPLQLGENLFTVSRQNQELKIKVIRVSTSPELPQGVAFAKDSLTPAADIARLPGELICFSALAKLPEGIAPPNANVSVTLANQTITLLPQPQQAQLPSNLAALTGQNQPYAQSSVGNYKGCTTVATAADLGKPQFQLTLNGKTITQPGTGKIQILSRAELPVSEVTVESGVARTGPSTDYSRLTPLPKGTRATVTGKEGEWLRLDYGAWINSQETRILPGAIPPQTIIRSVGYRQLPGATEIFFPLQVPVPVSVQQSEKALALTLYNTTAQTDIIRLDDDPLISRLDWQQEAPEQVKYTFNLKKAQQWGYKLRYDGTTLVLALRHPPNIGNTRRKLLANLKIVLDPGHGGKESGASGPTGYLEKDVNLVVSKLLRDDLVKRGATVVMTREDDKEVSLAERQAIISKEEPAIAISIHHNSLPDDGDAEKTKGFAAFWYQPQAHSLAIFLQTYVVKKLGKPSYGVFWDNLALTRPAAAPSVLLELGFMSNPDEFEQVVNPKEQKKMADAIAQGITEWFKSVR
>NZ_CP046703.1|WP_114084084.1|2470866_2471292_+|hypothetical-protein
MYFKIGGMVGAIAIFLSNGSAFTEGVGAAIAEGVGTAIAQDAQRYITVGHDKLGNSVALDTKTIKGTTYKLYGMYGDGIFETTFDASCSESRLFRNHIAIYSSEGQLLQEDKEKGEIPFVANSSPGKGMKIVCQKIGALGW
>NZ_CP046703.1|WP_114084083.1|2471407_2471983_-|pentapeptide-repeat-containing-protein
MNSRLSDCTAGSQLDSSRTQFGLKRQTDYHFWTNILSLFLWGMISITATLGFAPTALALEYNKEILVEADFSGRDLTDSSFTKANLRQSNFSHANLNGVSFFAANLESANLEAADLRNSTLDSARLVRANLTNALLEGAFAANARFDGAIIDGADFTDTLLRSDEQKKLCKLAKGTNPTTGRDTRDTLFCP

Crispr_ID: NZ_CP046703_8

• CRISPR_ID: NZ_CP046703_8
• CRISPR_location: 4209520-4209636
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP046703_8

Consensus_repeat	Method
ACTTGTGTGTACACCGTAGCCTTGTAAAGGGG	CRISPRCasFinder

spacers of NZ_CP046703_8

>8.1|4209552|53|NZ_CP046703|CRISPRCasFinder
GGAAATATCCGGTTCTCCCCGTTTATAAGGGGGAGTTAGAGGGGGTCAAAAGG

CRISPR arrays and Neighbor proteins around NZ_CP046703_8

CRISPR arrays

The CRISPR arrays of NZ_CP046703_8

>merge|NZ_CP046703|8|4209520-4209636|CRISPRCasFinder
ACTTGTGTGTACACCGTAGCCTTGTAAAGGGGGGAAATATCCGGTTCTCCCCGTTTATAAGGGGGAGTTAGAGGGGGTCAAAAGGACTTGTGTGTACACCGTAGCCTTGTAAAGGGG

>NZ_CP046703|8|8|4209520-4209636|CRISPRCasFinder
ACTTGTGTGTACACCGTAGCCTTGTAAAGGGG	GGAAATATCCGGTTCTCCCCGTTTATAAGGGGGAGTTAGAGGGGGTCAAAAGG
ACTTGTGTGTACACCGTAGCCTTGTAAAGGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046703.1|WP_114081775.1|4225399_4227091_-|aromatic-amino-acid-lyase	unknown	unknown	gnl|CDD|376303
NZ_CP046703.1|WP_114081777.1|4228148_4229318_-|MFS-transporter	unknown	unknown	gnl|CDD|341030
NZ_CP046703.1|WP_114081768.1|4201028_4201982_-|NAD-dependent-dehydratase	unknown	unknown	gnl|CDD|187540
NZ_CP046703.1|WP_114081766.1|4198585_4198966_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114081764.1|4195159_4196233_+|glycosyltransferase-family-4-protein	unknown	unknown	gnl|CDD|340831
NZ_CP046703.1|WP_114081781.1|4234269_4235643_-|phosphomethylpyrimidine-synthase	unknown	unknown	gnl|CDD|237359
NZ_CP046703.1|WP_114081773.1|4217648_4223270_-|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|225858
NZ_CP046703.1|WP_114081774.1|4223266_4225258_-|long-chain-fatty-acid--CoA-ligase	unknown	unknown	gnl|CDD|341259
NZ_CP046703.1|WP_114081780.1|4232107_4234096_+|S8-family-serine-peptidase	unknown	unknown	gnl|CDD|173822
NZ_CP046703.1|WP_114081767.1|4199691_4200780_-|3-deoxy-7-phosphoheptulonate-synthase	unknown	unknown	gnl|CDD|237376
NZ_CP046703.1|WP_114081765.1|4196245_4197031_+|WecB/TagA/CpsF-family-glycosyltransferase	unknown	unknown	gnl|CDD|224833
NZ_CP046703.1|WP_159402527.1|4202038_4202743_-|DUF4386-domain-containing-protein	unknown	unknown	gnl|CDD|379558
NZ_CP046703.1|WP_114081770.1|4202876_4203857_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114081779.1|4231018_4231630_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_147262488.1|4193006_4193240_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114081778.1|4229504_4230281_-|thioesterase	unknown	unknown	gnl|CDD|225749
NZ_CP046703.1|WP_159402528.1|4227905_4228031_-|PEP-CTERM-sorting-domain-containing-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114081763.1|4193690_4194389_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|372616
NZ_CP046703.1|WP_114081771.1|4204033_4208977_-|non-ribosomal-peptide-synthetase	unknown	unknown	gnl|CDD|341301
NZ_CP046703.1|WP_114081772.1|4209730_4217347_-|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|225858

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046703.1|WP_114081775.1|4225399_4227091_-|aromatic-amino-acid-lyase	gnl|CDD|376303	pfam00221, Lyase_aromatic, Aromatic amino acid lyase. This family includes proteins with phenylalanine ammonia-lyase, EC:4.3.1.24, histidine ammonia-lyase, EC:4.3.1.3, and tyrosine aminomutase, EC:5.4.3.6, activities.	1.75209e-178
NZ_CP046703.1|WP_114081777.1|4228148_4229318_-|MFS-transporter	gnl|CDD|341030	cd17477, MFS_YcaD_like, YcaD and similar transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MFS-type transporter YcaD, Bacillus subtilis MFS-type transporter YfkF, and similar proteins. They are uncharacterized transporters belonging to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.65439e-72
NZ_CP046703.1|WP_114081768.1|4201028_4201982_-|NAD-dependent-dehydratase	gnl|CDD|187540	cd05229, SDR_a3, atypical (a) SDRs, subgroup 3. These atypical SDR family members of unknown function have a glycine-rich NAD(P)-binding motif consensus that is very similar to the extended SDRs, GXXGXXG. Generally, this group has poor conservation of the active site tetrad, However, individual sequences do contain matches to the YXXXK active site motif, and generally Tyr or Asn in place of the upstream Ser found in most SDRs. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	6.9266e-135
NZ_CP046703.1|WP_114081764.1|4195159_4196233_+|glycosyltransferase-family-4-protein	gnl|CDD|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	1.57868e-56
NZ_CP046703.1|WP_114081781.1|4234269_4235643_-|phosphomethylpyrimidine-synthase	gnl|CDD|237359	PRK13352, PRK13352, phosphomethylpyrimidine synthase ThiC.	0
NZ_CP046703.1|WP_114081773.1|4217648_4223270_-|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|225858	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	0
NZ_CP046703.1|WP_114081774.1|4223266_4225258_-|long-chain-fatty-acid--CoA-ligase	gnl|CDD|341259	cd05936, FC-FACS_FadD_like, Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD. This subfamily of the AMP-forming adenylation family contains Escherichia coli FadD and similar prokaryotic fatty acid CoA synthetases. FadD was characterized as a long-chain fatty acid CoA synthetase. The gene fadD is regulated by the fatty acid regulatory protein FadR. Fatty acid CoA synthetase catalyzes the formation of fatty acyl-CoA in a two-step reaction: the formation of a fatty acyl-AMP molecule as an intermediate, followed by the formation of a fatty acyl-CoA. This is a required step before free fatty acids can participate in most catabolic and anabolic reactions.	0
NZ_CP046703.1|WP_114081780.1|4232107_4234096_+|S8-family-serine-peptidase	gnl|CDD|173822	cd07498, Peptidases_S8_15, Peptidase S8 family domain, uncharacterized subfamily 15. This family is a member of the Peptidases S8 or Subtilases serine endo- and exo-peptidase clan. They have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The stability of subtilases may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	2.5419e-97
NZ_CP046703.1|WP_114081767.1|4199691_4200780_-|3-deoxy-7-phosphoheptulonate-synthase	gnl|CDD|237376	PRK13396, PRK13396, 3-deoxy-7-phosphoheptulonate synthase; Provisional.	0
NZ_CP046703.1|WP_114081765.1|4196245_4197031_+|WecB/TagA/CpsF-family-glycosyltransferase	gnl|CDD|224833	COG1922, WecG, Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane].	7.1422e-82
NZ_CP046703.1|WP_159402527.1|4202038_4202743_-|DUF4386-domain-containing-protein	gnl|CDD|379558	pfam14329, DUF4386, Domain of unknown function (DUF4386). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 214 and 245 amino acids in length.	3.16844e-09
NZ_CP046703.1|WP_114081778.1|4229504_4230281_-|thioesterase	gnl|CDD|225749	COG3208, GrsT, Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism].	1.03011e-87
NZ_CP046703.1|WP_114081763.1|4193690_4194389_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|372616	pfam13489, Methyltransf_23, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.21497e-11
NZ_CP046703.1|WP_114081771.1|4204033_4208977_-|non-ribosomal-peptide-synthetase	gnl|CDD|341301	cd17646, A_NRPS_AB3403-like, Peptide Synthetase. The adenylation (A) domain of NRPS recognizes a specific amino acid or hydroxy acid and activates it as an (amino) acyl adenylate by hydrolysis of ATP. The activated acyl moiety then forms a thioester bond to the enzyme-bound cofactor phosphopantetheine of a peptidyl carrier protein domain. NRPSs are large multifunctional enzymes which synthesize many therapeutically useful peptides in bacteria and fungi via a template-directed, nucleic acid independent nonribosomal mechanism. These natural products include antibiotics, immunosuppressants, plant and animal toxins, and enzyme inhibitors. NRPS has a distinct modular structure in which each module is responsible for the recognition, activation, and in some cases, modification of a single amino acid residue of the final peptide product. The modules can be subdivided into domains that catalyze specific biochemical reactions.	6.34859e-170
NZ_CP046703.1|WP_114081772.1|4209730_4217347_-|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|225858	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	0

Protein sequences

>NZ_CP046703.1|WP_114081771.1|4204033_4208977_-|non-ribosomal-peptide-synthetase
MSTKSLELPIFSLVAKITGHDAEELERDMFLESNLGLDSIKMMELLNGLVALIPQERQPEFMETLPLQNLMQLQTLGDVVQIADKCLVSQIDNSDSSPSASIINQKEQKIEKVEILSGQYFHLLGHWVVNSISLFSTLRLRGDFDSNVAWQSWKDLLNRHPMLRSRFIIPPDTTRFKDYEMVVMENPTPPDIPVTDIRHLHSEAQEQLINDELHRCLNYEWQITEWPLHRFFVFRLEDSVYQLVLANEHLISDALGCHVILREFMEIYRAHICGEQPNLQPPTTVQDYSELVQSINAWQDPEEDKALVEYVNRRGKDSYLWNPTGNAITSLCPKFHNRRFSLGKTITNQLIAQTREWRLPLNSLLVGAFVRAVAKFEKSKNEPIMVQVPTSGRVYPGIDASDVVGSFAQNLSISLDLPALNEDWQRLLNRVHQEIQQGLVNGYDRAQTRQMAIAFRDNIVLEDGKIPERMLPMYRRILKSNLYCPFTGQTNIKNKYGPIDVIDYRAGGINAAGTIDILQEIFDDSLHLFASYDSNFFPESVIDELMQEYITQIKELASLKIPSQQLTQPLPKTQTDVNIVQLLQEIATEICHSQITDNDMAKDLEAELGMDSLELIRIVTRLEKRLGKVNRQALLSCRSLQEMAVLLGKKQSSSLQNQSVVNNQQPQEIPYWEIIEQAKRTPNAIAVTDGETQITYAELNRLSNQVANYLQSQGVKPGVFVGIMTRRGPLMFVGILGILKAGGTYVPLDPIYPHERIKYILEHAEIGILLTENRLKNKLAECLTEQLPLNTLMFLDEGIFEQGKAWTQLNKKTWARCSDIAPANVNTPDNLMTVLYTSGSTGKPKGVMLNHRGYMNRLVWMQNAFQLRYGDRVAQKTSCCFDISVWEIFWPLMVGATVYSVETETVKNPWLLAQWIKDNQINVMHFVPSLFGEFCNALESELWTFPDLRWLVFSGEALPVPFVQRWIDKYGMSVGLANLYGPTEASIDVTAHIIRQRPGEQEICIPIGKAIDNVYILILDEQMQPLAPGKMGELWIGGVQLAKGYLKDPQRTADAFRLNPFSHVPGEYLYKTGDLAMELPDGSFEYHGRIDHQIKIRGFRVELGEIESVLNSHPAINEAAVLAVDYENGQKRLIACLAGSQVDNQQIKEFLAQRLPDYMIPHRWEWLASLPKTHNGKLDRKAILAAITQEKPTVSQEYLPLGPAQRWLVKYFEAPYQWNGYTRFLFHQPLDPEIFNQALNFVLETHPALRTVFVQRDQQWWQQLISPEQKLSAEFYDGSHLTSAQRDSEIHNRIQEIAQQFQIDQWPLMKVIAIKVNESCYDISLVGHHIIGDLLSTGVIFNLLWLTYSELLGNRTQSSQPLPSTPSYIDYVRVLMQAEQQGALTSHVDYWKSQFPSQEYTFQVPFDHQKGANLEASAASEKFTLSKNSSNILLREAKQYYKCNVYTLLLSTLYRLMAEWSGQHWVVVSHRSHGRNLDSTHTFLNSVGNFAMNFPVGVNVGRSIKWEQTTKEIQAKFNELPMNGVTFDWISEQLPHHVYPDNNLTPVRANYLGNRTAPALELFKFIEEDRDSRLSSPDQKRTALLEFFFSITDGTVHLEIEYSCNFHLPATIRRLGDRYLELMAEMLAVVPLVGNVVEVTNHFHKSY
>NZ_CP046703.1|WP_114081770.1|4202876_4203857_-|hypothetical-protein
MRTYQLSKLIGFATSVALSATAPAQAANLSFDYNQLQFIKSRPTASSNFLGLNGSPIENQGFVPFYNPDPSAPDHGHKEIGLNSRRDFPGFNNAPYYGTGRQGSPEEPASGATRMTSLISINSFPTFGQYLTNYGIPLNDIGFVFGQKSDRNFNQTWNLGADIFGQNWYADPNTPLEERIYKANPNDVEIALYSGNTKIVDFGYSDFYSIIDYGDTPSFDDDFESSFTDPIAAKKASNLDPLLAGLATAFLNDVNAAGGGVQIVNENFGELDINFASGNGYDMILLPYPMQIRAVALKAVPEASFSWGIFMFGVLVAVSQRKKLQN
>NZ_CP046703.1|WP_159402527.1|4202038_4202743_-|DUF4386-domain-containing-protein
MSIKALYRTAGLVLIVESLLLFVPVFILGAAINWPASLGEPASIMLPLLIEKAEPVRIGYLIYLLYSILFWVVALLTARVISNGETNPVWLQVATGFGIASTVTRCLGIIRWLVPMPALAQVYADPAISAQTREAIAVVYKTLNDYAGSVGEVLGVSLFTVLWLTIISIYLLRSRTLPRWLGIFGIIAALFLATQLIELFGVDLGAFISVSVTMLQLWFLAAGVTLLRHKNVQV
>NZ_CP046703.1|WP_114081768.1|4201028_4201982_-|NAD-dependent-dehydratase
MNTTEELHVIFGTGPLAQAVMRELLARNKRVRMINRSGKADVPSNVEIIASDAYNSENTRAVTTGATVVYQCAQPAYTQWPEFFPSLQASIVEGVAASGAKLVVGDNLYMYGPVNGALQEDMPNAATTRKGRVRGQIAEALLDAHRRGIVRVAIGRASDFYGPLVLDSVMGDRIFPSVLTGKPASAIGEIDLPHTYTFIDDFGKALVVLGEQDKALGQIWHVPNAETLTTRQFINIAFEEAGHPPKISKMGKFMMRLGGIFIPEARETVEMMYEFDEPFVVNHDKYVQAFGNHATPLREAIRHTLTWYSEHLETLKT
>NZ_CP046703.1|WP_114081767.1|4199691_4200780_-|3-deoxy-7-phosphoheptulonate-synthase
MIIVMKPFTPSAEIEQVNEEIRRHELTPEICVGHHKVVIGLVGDTSELDPRQIQNLNPFIEQVIRIKKPFKRASLEFRYGEHSEVVVPTPNGPITFGQNHPVVVVAGPCSVENEEMIVETAQAVKECGVQFLRGGAYKPRTSPYAFQGHGESALALLAKAKEATGLGIITEIMDTDDLDKLIEVADVLQIGARNMQNFSLLKKLGATTKPVLLKRGLSATIEDWLMSAEYILAGGNPNVILCERGIRTFDRQFTRNTLDISAIPVLRTLTHLPIMIDPSHATGKSEFVPTMTMASIAAGADSLMIEVHPNPAKALSDGPQSLTLEGFKELMHEITALSKFFGRSSHNNSKNLKPKAISLVSY
>NZ_CP046703.1|WP_114081766.1|4198585_4198966_-|hypothetical-protein
MSTVSKLTQLKKGLETSEVQKGMKLIGLQITELELDQLAFGNTISLENRRLGEIGSIFILAEALSAVNSVQTNITFQDLPQTLKEFSCCYGGVTIYCWNSDLIGKCCLTLTLLDGKPAIRVSSQNL
>NZ_CP046703.1|WP_114081765.1|4196245_4197031_+|WecB/TagA/CpsF-family-glycosyltransferase
MRINICGVEIDKYSFDEVVEQIINHALSQRKPEYVVTPNAMHIVTLQKDVDFQEIYRKAFLVVPDGVSLLWAAKFLQTPLSGRVNGTDLFEKLCAIASEKGLKVFLLGGRPGSAEKAKKTLVARHPSLQIVGTYCPPYGFESQLTELNSINSTIIEAAPHILFVGLGAPKQEKWIAANYLYLGVPISVGIGVSFELVSNMVTRAPVWMQKAGFEWLFRLLVEPSRLWKRYLFGNYTFIGLLIKQRLGLFKRLSNTKRSDRF
>NZ_CP046703.1|WP_114081764.1|4195159_4196233_+|glycosyltransferase-family-4-protein
MKQIQVLMLGPSLEQNGGIATVEKLIIKHNLPQFKIQHISTHDEGSIAYRLIVFAKALTTFLWKLSSQEIDIVHIQISDGGSIFRKAICCVIAFLFDKPVLMHTHGAEFHLTYAKLPQIVQQVLSKVFQHCQGFVVLSESWQDYYVLNLGLNPKQVIVLPNPCELPTEVPERKNRTQISLVCCGRVGQRKGTFDLIKAFANLPNHQKKYTQLILAGDGEIEKAQQLAASLNLSDQVTFLGWINSEKRDEVLSQADVFILPSYNEGLPLAILEAMGWSLPVIATPVGGISELVISNQNGLLVTPGNIKQLSSAMELLIENENLRLFLGSNARKNVEPLDIKNCSIRLADIYNSLSQFN
>NZ_CP046703.1|WP_114081763.1|4193690_4194389_+|class-I-SAM-dependent-methyltransferase
MNTIYEDGTYLQNHPTWHEEDSPWKAKQIAKIIKRNNLNPLTICEIGCGAGEILNSLQTEFSDKTSFYGYEISPNAFEICNSKSNKKLHFFLKDLLNEKEAIFDLVMAIDVFEHVEEYFGFLRKLKEKGKYKLFHIPLDLSVQTVLRSSPILKDRLLYGHIHYFTKETALATLKDTGYEVLDYFYTCPCLELQNRGGWKSSLLNVPRKLLFSINQDLAVRILGRFSLLVLAK
>NZ_CP046703.1|WP_147262488.1|4193006_4193240_+|hypothetical-protein
MGFRRDTARLDNRCTEYPENSDDLRSVGDHRSKGWFHLKLGGEADSKIERVFLCDSPIDALTMADINIQGHLGQLPD
>NZ_CP046703.1|WP_114081772.1|4209730_4217347_-|SDR-family-NAD(P)-dependent-oxidoreductase
MSNTSDINQLSPLQRSVLALKEMRAKLDAVENAKTEPIAIIGMNCRFPGGADYPEKFWELLHNGVDTITEVPADRWDVDEYYNANPNTLGKIYTRYGGFIKQVDQFDPHFFGLSPLEAASMDPQHRLLLEVGWEAVENAGQSPEELNGSQTGVFMGLFMEDYSRFNLYSGDHNRIDAYSSLGNARSIAIGRLAYVLGLQGPVMQLDTACSSSLLAVHLACQSLRSGECNMALAGGVNLILAPEASIGLSRMRALAPDGRCKTFDAKADGYVRGEGCGIVVLKRLSDAIANNDNILAVVRGSAVNHDGASSGLTVPNGLAQEKLINQALTNAKVAPEQISYVETHGTGTSLGDPIEVRALGSVLCQGRSPEQPLLIGSVKTQLGHLESAAGVASLMKVVLALQNAEIPPHLHLQQPSPHIPWDKLAVAVPTKPTPWPAVNGKRLAGVSSFGMSGTNAHLIIEEAPKLKLEPPKTERPLHLLSLSAKTEAALLAMASRYESFLTSHPETSLADICFTANTGRSHFEHRLAVVAASNTDLREQLTAFASQKQTSTLVSGQAQKKRSKVVFMFTGQGSQYVEMGRQLYETQPTFRKTLDRCDEILRPYLQQPLLSVLYPTSDVASPLNETAYTQPALFALEYSLAEMWKSWGIVPDAVMGHSVGEYVAACVAGVFSLEDGLKLIAERGRLIQSLPQNGMMAAVFTNEARMNGILATYTGQVAIAGINGPENIVISGAREAVQAVLKELATQGINAQPLQVSHAFHSPLMASILDPFEQIASSVQFQAPRIPLISNLTGQILKYQEIPNATYWRQHLREGVRFYAGIKTLHEQGYEIFLEMGPSTTLVGMGKRCLPEGTGTWLTSLKKGQPDWSQLLASLSELYIRGIKINWTAFDQGYQRRRLALPTYPFQRQRYWVENPPSLPGENSKPLSLQEKSLPAIPQVKALPRIPLAVPSNWFHSWQWTPEVSSQSQDIPSGAILIFSDRHQVGENLEKLFDSKKYTTYIVTPGESFTQTAQHFTINPASVADYEQLIKNIKADGVTVTAAVHLWNYSLWATSPGQLLENDRLLNERVYSLLFLTQALVKHYPASPLNFLVVTQGAYPISPNDSLHAVHQSMAGVLAQVVAQENPQIQAKVVDFNQDVYLPEKLADILFQEMKAAPTGEGIVAIRNGQRLSRTLEKINVSTDNNSLPLSPGETWLITGGTSAVGTEIALALVRQVPINLVLTGRHPLPPKQEWQSASHDSSTQQRIQAIEQLEQLGATVMYQAVDVTDALGMKQLIENIKSRFGNLDGVIHAAGAVDHSTFKLLQKQPASITKVLAPKVQGTIILDAVTRNEPLKYFVLLSSVSASKAEWGTGMGDYAAANTFLDSYAVYRTQHGGQGRSLALNYSLWSDRGMGALLGASTLLMVKSKGLNPLEPEPAANAFIKALSLDASGVIHIIDLIAQATPEIAPKSSASQPQTKSRNLRQLVREVLLQHLRIPEAQVEGHKTFQEMGLDSVGTVEVVQHLGTTLGEELFPTLLFEYQTPDDLVDYLQSKYGYSVKTSTSAIAPEETSSPEAEKSAPPNVATQEKYQDVPEQDIAIIGMACKIPGADNLEQYWDLLNAGRSVIQDVPQDRWFNQHYFEAKGNSPQAKISKRGCFVNSPFDFDPMFFGISPKEATAMDPQQRLFLELSMQALQQAGYGGKYRPDNIGVFVGCGQNTYIEHFTNYQYYEELRQRLQESSWFDHLPAEDRQHLLKTLSQVLQPSEILPESAAGNEVNELAARVSHCLNLKGPSMAVSTACSSSLVALHIACESLRSGQTGMAIVGGVNLNLSPSPFTFLRKAQALSVSGTCYPFDRRANGIVLGEGAGVLIIKPLKQALADGDLIHAVIKGSAVNNDGHSQGITAPNPKGQAEAIRQAYNSCGVDPRTISYIETHGTGTLLGDPVEVEGMTQAFRSFTDEKGFCTIGSVKSSIGHLLSASGIVSLIKVVLAMQHGKIPQTVGFEEPNPHINFADTPFAVAGKSIPWSPNGNPLRAGVNGFGFGGTNCHVILEESPLAANLQSQVTSSAPDLLCLTARNQQALQEVARQLREHIIHHPEQESSQICFTQNNAQKELPYKAALVVNDRQHLLNYLEAICSAQTPAGIYTGRANPQRTTPFHLVLDGTSAIAPAEVETLGKRFPQFQVAYNSVRAGLNEMSEQAHIFAVQYAWGRLLMSLELQPTSLLVEKTGILVGATLRGMLTLEQAITLLLQIEGQKGLIAHNVSAKERLASTWTCPLVTSQGIFSHSDTISTAQLVAPVQVSEQLNVDVCQDVISKESVYLHLGDSLALKEKLASLDELGVWIYLDKGQPVVGRVLTSLARSYVAGVRFNSIPLFPQGLRRVLLPTYPFERKTYRVSLVDSTQENQATSIPAAELLPPRLDNQHQSNAKVLETHPVTVAQTRLLPIEQLSPLTDSQRQSSYAKLAEDLKIVDNSQQPRLLPIEKPSPLTDSQRHSSYTKLAEDLKIVDNSQQPRHPIAVAQTRLLPMEQLSPLTDSQRQSSYIKLAQDLQRFGK
>NZ_CP046703.1|WP_114081773.1|4217648_4223270_-|SDR-family-NAD(P)-dependent-oxidoreductase
MSPNSENTNYRLLLENAILELRRMRSEVDTVEQLQKEPIAIIGMSCRLPGGVNNPEDYWNLLHNGVDAISKIPAQRWPVDEFYHPDPDVLGKMYTQHGGFLNEVDKFDAQFFGISPREAVSLDPQQRLLLEVTWEALENAGQAPEKLNGSPTGVFVGLSMDDYAQLSFYGDRTQIDAYNTLSILRSMAAGRLAYVLGLQGATMQLDTACSSSLLGVHLACQSLRSQECNMALAGGVNLILSPDPSIGLCKLKALSTDGRCKTFDASADGYGRGEGCGIVVLKRLSDALADGDPILALIRGSAYNHDGSSNGLTAPNGSAQEKLLRKALENANVQAHQIQYVETHGTGTPLGDPIEVLALGAVLGQGRSEDNPLTIGSVKTQVGHLESAAGVAGLMKVVLALQHTEIPPHLHFQQPNPYIPWEKLPVVVPTQPTKWPLGADGRRLAGVSSFGMSGTNVHLILEAAPEIKSVQAKTERPLHLLSLSAKTESALQSLVSRYESFLAGDSKANIADICFSANTGRSHFDHRFAVVAESTQDLRQQLAAFAAGKTPAVSGQLHNKKRPKIAFLFTGQGSQYISMGRELYETQPTFRQTLDRCDEILRPYLEQPLLSILYPESGTSPLNETAYTQPALFALEYAVSQLWKSWGIEPTVVMGHSLGEYVAACIAGVFSLEDGLKLVAIRARLMQSLPQDGAMVNIFASQARVFAAIQPYADQVSIAAINGPESVVISGQHQAVAAVMSTLQSEGVNSVKLNVSHAFHSPLMEPVLAEFERIAAEVSFSLPNIKLISNVTSTVVTTEITNAEYWVRHLRQSVRFASGMETLEQQGCEIFLEVGPKPILLGMGRKCLPEGVGVWLPSLRPGQSDWQQLLQSLQELYLRGASINWSGFDQDYPRRRLVLPNYPFQRQRYWVETSHRQQTLPAKTSKTLHPVLGHRLKLPFSPEIRFETQFSLNSPAYLEDHQLNEVRIVPGASYISMLLSAVKEAFPNESCIIEDLLFQNTLVCPDDGSTTVQLVLTPQTTEETSFQLISFLGGEAENEVNWKTHGTGKVRLFSPVPNFVDVAEVKARCSQVLSGTQFYSSFQAVGYSWGTSFQWLENIWHQDGEAVCQMKLPQLQDELDNYQLYPGLIDSCLQLLNVCWDVNPAEQVQNDYMYIPFSIGSFRFYGRSHPGHQLWCHGQKTPTSNQQSLIGDVHLFDQNGQLIAEIIGFEVRKVRRATLLQSLQKDLGDWLYEVAWQSKPREQNHQLAQAQEGSWLIFADQQGTAVKLAKLLKERGDRTILVSPGAEYQADAEHYYINPSEPQDFQRLIQASLGNNQPPCRGVVYLWGLEETLETLNTGCGNVLHLVQALAKSTWSKSPRLWLVTRGTQPVEPMSDSLAINQAALWGLGRVIALEHPELSCVRLDLDPNGNGNEIEELLAELLFPDQEDEVAFRQGVRKVSRLVRRQAQTPANQLAIGEDGTYLITGGLGALGLQVAQWMVAQGAKNLILTGRRGVVGDTQVAINQLQQAGAKVLVVTADVSNTEDVAQMLEAIKANYPPLRGIFHAAGVLDDGVLLQQNWSRFAKVLAPKVQGAWNLHTLSKDLPLDFFVCFSSVASLLGSPSQGNYAAANAFMDALVHYRRGLGLPGLSINWGPWAEVGMAADLDSRSQQRIAESGFATMSSELGLQLLGDLLRQDATQVGVMSVNWAKFLQQFPPGGAAPLISDLAPQTQPQTNSAQSAKQLELLRQLEETIASDGLRPAVGDRQNVLIAYIQTEVAQVLRFEAAYQPNPQQGFFDMGMDSLMSIELKNRLETSVGNSLPSTLTFEYPTIESLAEYLLNNVISLNVAEPVVVEPQIETEVQNDLLIDIQQYSEDELAALVDQELEALLGV
>NZ_CP046703.1|WP_114081774.1|4223266_4225258_-|long-chain-fatty-acid--CoA-ligase
MNISQNVERGCCLFPNKPALIFEGLYFTYKQLNEMANRFANALLGLGIERGDRIALLLPNIPEFVISYLGILKIGAIAVSINPSLQSDELKFILNDCGAVVLVTTETLREKLPKQDLPHLKHILIAEGKASDAIALSEFMANASSSARAVEMERDDPAAILYTSGTTGFPKGATLSHGNVISNMHSMNHCCEMRPNDQILLFLPMFHCFGQNAVLNSGLNTCATIVLQRSFDPETVLTTISEYNITIFFGVPTTFILLCDKASIRDLDSVRYYFSAAAGLPIEIAKRWQDKFGKVINQGYGLTETSPLASYNHELRYKLGSIGSPIENVEMKIVSLDDGCEVAPGELGEIVIRGVNVMLGYWNRPAETAKAIKNGWFHTGDIGQIDELGYFYIVDRLKDMINNGGLKVYPAEVENVIYQHPGIAEVAVYGVPDSILGEQVKASVVLKPDQVVTEEEIIAFCYQKLAKYKVPSAVEFVSSIPKNPTGKILKRLLRQENSAASSHSTVVSKTQTSASVNVSYQTAELIENWIMDWVVRKLAVAAQSIDQSKSFADYGLDSVRAVKLAQELSEWLGYPLEATIVWNFSTIESLASHLASQKIPQPTELAKTKPESNLHTESLLVSVELLTNKAELTESADLKALSDAEIAELLTKEIATVKQRRLV
>NZ_CP046703.1|WP_114081775.1|4225399_4227091_-|aromatic-amino-acid-lyase
MKTLSQAQSKTLPQQFSFTGNSSGNVIIGNQKLTINDVARVARNGALVSLTDNADVLQNIHASCDYINNAVESGEPIYGVTSGFGGMANVAISREQASELQTNLVWFLKTGAGNKLPLADVRAAMLLRANSHMYGASGIRLELIKRMETFLNAGVTPYVYEFGSIGASGDLVPLSYITGSLIGLDPSFKVDFNGKEMDAPTALSQLNLSPLTLLPKEGLAMMNGTSVMTGIAANCVYDTQILTAIAMGVHALDIQALNGTNQSFHPFIHNSKPHPGQLWAADQMISLLANSQLVRDELDGKHDYRDHELIQDRYSLRCLPQYLGPIVDGISQIAKQIEIEINSVTDNPLIDVNNQASYHGGNFLGQYVGVGMDHLRYYIGLMAKHLDVQIALLASPEFSNGLPPSLLGNRERKVNMGLKGLQICGNSIMPLLTFYGNSIADRFPTHAEQFNQNINSQGYTSATLARRSVDIFQNYMAIALMFGVQAVDLRTYKKTGHYDARVCLSPATERLYSAVRHVVGQKPSSDRPYIWNDNEQGLDEHIARISADIAAGGLIVKAVQDIC
>NZ_CP046703.1|WP_159402528.1|4227905_4228031_-|PEP-CTERM-sorting-domain-containing-protein
MNGTFATVPEPNTLIILISLGIGGVGALLSRCYREEHEKAS
>NZ_CP046703.1|WP_114081777.1|4228148_4229318_-|MFS-transporter
MTELISTKSNSPFSTGLPALYSIAFLSGISIGLFNPFISTLMAQHQVDDLWIGANSTVYFLVIALGTPFVVKVLPKLGLRKTMMLGLTMMGISAPLFTMTTSMPLWFIIRAVMGIACCLYLVSGNTALNHFCHEGNRAIVNGLNALAFTFGFGIGPVIGSALYNVSPKLSFLLGSALIFSGVIVVWIALPDKAVVFQQSSRSGIFNKLKLPLQGAFAYGFAESTLVSLYPVYLLRQNYNIEQIGYTFAVFVVGGLLSTVPVTHIADKFGRLKVLFMSVSIVILSFLSLSLIQNSTATQIFAFIAGASISPIFPIAMALIGAKLSRNELSSGSALFTAIYSFGCTAGPIASSLAIKVFGDGYIFSLTIIIFAVFLFYVGRQNKKFPFRIT
>NZ_CP046703.1|WP_114081778.1|4229504_4230281_-|thioesterase
MTAKLIVDPWISCPQLNPKAQLRLFFFPCAGGTTSTYSTWTNKLPKDVEVYLVQLPGRGRRLQEPSYTNFLPLIQTLASKIRPYLNMPFAFFGHSMGATLGFEIARLLRHEYNLSPVHLFAACCPAPQKPILKPFIHKMPEAKFLAELCDRYNAIPNEILQNEQMLQLFLPCLRADFTILETYIYKSEMPLECPISVFGGLQDKAIKVDALEAWREQTSSYFNLQMFPGDHFFLHNSQSLFLQSLSQHLNYLVAINNN
>NZ_CP046703.1|WP_114081779.1|4231018_4231630_-|hypothetical-protein
MFYFPAEYFLQVYSLPLIAEVKFQNDYFSEYPEQIRVGSDSTAISYTRKSGYYAIHYNNQPKTVAPGAILQLNDGAMSTMVTEPCRSAGYAYAVFPGEPNQSEQGKLSPVYTIEPNGSLAVPTGLVFIRFAEGVDVKSQHEAINRAGYEVVESLDYAPHAAWLRAQSGNIADAIAKIPQLEAIPKVENIEPQMLMERGLRQGR
>NZ_CP046703.1|WP_114081780.1|4232107_4234096_+|S8-family-serine-peptidase
MVQVRYGGQNGQQYELAISDEHVVVRTESRSTLIGARPFEVAPVSPTARSILSQFELTMRFRQAGVEILRAKVPTQGVALRDRAREILNQESEVQFAGRVLIDPASNQPIIYTENLFVKFDNEEESRVCQEILRRYSLTIKRQLEYARNAYFVNAPTNTGIAIFDIAERLLNEESVELCHPELVRESRQRQVFPQQWHLKQTTINGKVINAHANVEAAWKLSDGTGTIIAIIDDGVDLDHEEFRSSGKIVAPRDVTRKNDNPRPGNDNNHGTACAGVACGNGKFGASGVAPGAKLMPIRLASSLGSQDEADAFIWAAQNGADVISCSWGPADGTWFEPNDPLHKQKVPLPDSTRLAMDFAINKGRNGKGCVILFAAGNGNESVDNDGYASYQKVIAIAACNDFGTRSAYSDFGQAVWCAFPSNNGDSSQTPGIWTTDRVGVLGYNSGNVNLGDAGGNYTNEFGGTSSACPGAAGVAALIIARNPNLRWDEVRDIIKRSCDRIDQAGGKYDANGRSPFYGYGRINALKAVELAKPAQTSPISIFKAVQDIPINDLQTSTLSLAIANTSLMKSIKVNVDIEHTYIGDLVVTLLPPVQIGILPIVLHDRQGGATDNIKTTYDEVNTPKLAAFKGKSPQGTWTLEVADKASTDTGKIRSFTIEIGF
>NZ_CP046703.1|WP_114081781.1|4234269_4235643_-|phosphomethylpyrimidine-synthase
MRTEWVAKRRGQSNVSQMHYARQGVITEEMHYVAQRENLPADLIRDEVARGRMIIPANINHTNLEPMAIGIASKCKVNANIGASPNSSNLQEEVDKLNLAVKYGADTVMDLSTGGGNLDEIRTAIIKASPVPIGTVPVYQALESVHGTIENLTADDFLHIIEKHAQQGVDYQTIHAGILIEHLPLVRNRITGIVSRGGGILARWMLHHHKQNPLYTHFQDIIEIFKRYDVSFSLGDSLRPGCTHDASDEAQLAELKTLGQLTRKAWEDDVQVMVEGPGHVPMDQIEFNVRKQMEECSEAPFYVLGPLVTDIAPGYDHITSAIGAAMAGWYGTAMLCYVTPKEHLGLPNAEDVRNGLIAYKIAAHAADIARHRPGARDRDDELSKARYNFDWNRQFELSLDPERAKEYHDETLPADIYKTAEFCSMCGPKFCPMQTKVDADALTELEKFLAKEPVTQS

Crispr_ID: NZ_CP046703_9

• CRISPR_ID: NZ_CP046703_9
• CRISPR_location: 4930753-4931585
• CRISPR_type: Orphan
• Repeat_type: I-D,II-B
• Spacer_info: 11 spacers

Consensus repeat of NZ_CP046703_9

Consensus_repeat	Method
ATTGCAATTCATCAAAATCCCTATTAGGG----------ATTGAAAC	PILER-CR
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC	CRISPRCasFinder
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC	CRT

spacers of NZ_CP046703_9

>9.1|4930790|34|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT
ACGAGTAGATTGAATCTGTTTGCCATTCCACAAC
>9.2|4930861|36|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT
GTAAGTACTTTTCTTTGATTACGGCGAGGGCACAAT
>9.3|4930934|31|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT
ATTTACATTTGTTGGATCTGCCTTGAGGAAA
>9.4|4931002|35|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT
ATTTACTTTCATTTACGCTGATAAACAGCAAGTAT
>9.5|4931074|37|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT
CCGCCATCACCCCAGACTTACACAGAGGAAGAGCTAC
>9.6|4931148|35|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT
GGGAAATTTAATTCTTTTAATCCTAAAGTGCTAAC
>9.7|4931220|37|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT
GATATGGTGACAAATAACCCTGTAGCCGCCGCCGCTA
>9.8|4931294|36|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT
GTGTAAAAACAAAACATAAAAATCCCAAGCCTTGAT
>9.9|4931367|35|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT
GAATACTTCAAATACTCGCACCAAAAACCGTATCA
>9.10|4931439|39|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT
TTCTCTCGTGTTGATGTAGACCAAACTGGGGTAACTGGC
>9.11|4931515|34|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT
TAGCAATACCACTCGGTGAAGTTCCAGAGGTAGC

CRISPR arrays and Neighbor proteins around NZ_CP046703_9

CRISPR arrays

The CRISPR arrays of NZ_CP046703_9

>merge|NZ_CP046703|9|4930753-4931585|PILER-CR,CRISPRCasFinder,CRT
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAACACGAGTAGATTGAATCTGTTTGCCATTCCACAACATTGCAATTCATCAAAATCCCTATTAGGGATTGAAACGTAAGTACTTTTCTTTGATTACGGCGAGGGCACAATATTGCAATTCATCAAAATCCCTATTAGGGATTGAAACATTTACATTTGTTGGATCTGCCTTGAGGAAAATTGCAATTCATCAAAATCCCTATTAGGGATTGAAACATTTACTTTCATTTACGCTGATAAACAGCAAGTATATTGCAATTCATCAAAATCCCTATTAGGGATTGAAACCCGCCATCACCCCAGACTTACACAGAGGAAGAGCTACATTGCAATTCATCAAAATCCCTATTAGGGATTGAAACGGGAAATTTAATTCTTTTAATCCTAAAGTGCTAACATTGCAATTCATCAAAATCCCTATTAGGGATTGAAACGATATGGTGACAAATAACCCTGTAGCCGCCGCCGCTAATTGCAATTCATCAAAATCCCTATTAGGGATTGAAACGTGTAAAAACAAAACATAAAAATCCCAAGCCTTGATATTGCAATTCATCAAAATCCCTATTAGGGATTGAAACGAATACTTCAAATACTCGCACCAAAAACCGTATCAATTGCAATTCATCAAAATCCCTATTAGGGATTGAAACTTCTCTCGTGTTGATGTAGACCAAACTGGGGTAACTGGCATTGCAATTCATCAAAATCCCTATTAGGGATTGAAACTAGCAATACCACTCGGTGAAGTTCCAGAGGTAGCATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC

>NZ_CP046703|9|2|4930753-4931585|PILER-CR
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC	ACGAGTAGATTGAATCTGTTTGCCATTCCACAAC
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC	GTAAGTACTTTTCTTTGATTACGGCGAGGGCACAAT
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC	ATTTACATTTGTTGGATCTGCCTTGAGGAAA
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC	ATTTACTTTCATTTACGCTGATAAACAGCAAGTAT
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC	CCGCCATCACCCCAGACTTACACAGAGGAAGAGCTAC
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC	GGGAAATTTAATTCTTTTAATCCTAAAGTGCTAAC
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC	GATATGGTGACAAATAACCCTGTAGCCGCCGCCGCTA
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC	GTGTAAAAACAAAACATAAAAATCCCAAGCCTTGAT
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC	GAATACTTCAAATACTCGCACCAAAAACCGTATCA
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC	TTCTCTCGTGTTGATGTAGACCAAACTGGGGTAACTGGC
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC	TAGCAATACCACTCGGTGAAGTTCCAGAGGTAGC
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC

>NZ_CP046703|9|9|4930753-4931585|CRISPRCasFinder
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC	ACGAGTAGATTGAATCTGTTTGCCATTCCACAAC
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC	GTAAGTACTTTTCTTTGATTACGGCGAGGGCACAAT
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC	ATTTACATTTGTTGGATCTGCCTTGAGGAAA
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC	ATTTACTTTCATTTACGCTGATAAACAGCAAGTAT
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC	CCGCCATCACCCCAGACTTACACAGAGGAAGAGCTAC
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC	GGGAAATTTAATTCTTTTAATCCTAAAGTGCTAAC
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC	GATATGGTGACAAATAACCCTGTAGCCGCCGCCGCTA
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC	GTGTAAAAACAAAACATAAAAATCCCAAGCCTTGAT
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC	GAATACTTCAAATACTCGCACCAAAAACCGTATCA
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC	TTCTCTCGTGTTGATGTAGACCAAACTGGGGTAACTGGC
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC	TAGCAATACCACTCGGTGAAGTTCCAGAGGTAGC
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC

>NZ_CP046703|9|2|4930753-4931585|CRT
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC	ACGAGTAGATTGAATCTGTTTGCCATTCCACAAC
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC	GTAAGTACTTTTCTTTGATTACGGCGAGGGCACAAT
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC	ATTTACATTTGTTGGATCTGCCTTGAGGAAA
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC	ATTTACTTTCATTTACGCTGATAAACAGCAAGTAT
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC	CCGCCATCACCCCAGACTTACACAGAGGAAGAGCTAC
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC	GGGAAATTTAATTCTTTTAATCCTAAAGTGCTAAC
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC	GATATGGTGACAAATAACCCTGTAGCCGCCGCCGCTA
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC	GTGTAAAAACAAAACATAAAAATCCCAAGCCTTGAT
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC	GAATACTTCAAATACTCGCACCAAAAACCGTATCA
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC	TTCTCTCGTGTTGATGTAGACCAAACTGGGGTAACTGGC
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC	TAGCAATACCACTCGGTGAAGTTCCAGAGGTAGC
ATTGCAATTCATCAAAATCCCTATTAGGGATTGAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046703.1|WP_114081909.1|4920654_4922430_+|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NZ_CP046703.1|WP_114081915.1|4928796_4928967_-|hypothetical-protein	unknown	unknown	gnl|CDD|177653
NZ_CP046703.1|WP_114082006.1|4932788_4933622_-|Rpn-family-recombination-promoting-nuclease/putative-transposase	unknown	unknown	gnl|CDD|371375
NZ_CP046703.1|WP_012410339.1|4928176_4928470_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114081914.1|4926867_4927875_-|WD40-repeat-domain-containing-protein	unknown	unknown	gnl|CDD|238121
NZ_CP046703.1|WP_114081924.1|4940938_4942171_-|glycosyltransferase-family-4-protein	unknown	unknown	gnl|CDD|340831
NZ_CP046703.1|WP_114081922.1|4939727_4939940_+|thiamine-biosynthesis-protein-ThiS	unknown	unknown	gnl|CDD|180978
NZ_CP046703.1|WP_114081923.1|4939936_4940818_-|class-D-beta-lactamase	unknown	unknown	gnl|CDD|225322
NZ_CP046703.1|WP_114081918.1|4933743_4934601_-|acyl-CoA-desaturase	unknown	unknown	gnl|CDD|224316
NZ_CP046703.1|WP_114081910.1|4922766_4924266_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114081920.1|4936085_4937987_-|DUF1565-domain-containing-protein	unknown	unknown	gnl|CDD|284923
NZ_CP046703.1|WP_114081919.1|4934774_4936004_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_CP046703.1|WP_114081912.1|4925152_4926208_-|permease	unknown	unknown	gnl|CDD|223773
NZ_CP046703.1|WP_114081921.1|4938483_4939599_+|thiamine-phosphate-synthase	unknown	unknown	gnl|CDD|235054
NZ_CP046703.1|WP_114081925.1|4943054_4944038_+|DUF1517-domain-containing-protein	unknown	unknown	gnl|CDD|226808
NZ_CP046703.1|WP_114081916.1|4929384_4930476_+|alanine-dehydrogenase	unknown	unknown	gnl|CDD|240630
NZ_CP046703.1|WP_114081907.1|4917932_4918715_+|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl|CDD|376667
NZ_CP046703.1|WP_167756019.1|4919060_4919591_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NZ_CP046703.1|WP_114081911.1|4924325_4925099_-|TIGR03943-family-protein	unknown	unknown	gnl|CDD|274870
NZ_CP046703.1|WP_114081917.1|4931656_4932712_-|tRNA-dihydrouridine-synthase-DusB	unknown	unknown	gnl|CDD|129820

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046703.1|WP_114081909.1|4920654_4922430_+|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	7.08863e-41
NZ_CP046703.1|WP_114081915.1|4928796_4928967_-|hypothetical-protein	gnl|CDD|177653	PLN00014, PLN00014, light-harvesting-like protein 3; Provisional.	2.99382e-05
NZ_CP046703.1|WP_114082006.1|4932788_4933622_-|Rpn-family-recombination-promoting-nuclease/putative-transposase	gnl|CDD|371375	pfam11103, DUF2887, Protein of unknown function (DUF2887). This bacterial family of proteins has no known function. These proteins may be distantly related to the PD(D/E)XK superfamily.	7.96217e-109
NZ_CP046703.1|WP_114081917.1|4931656_4932712_-|tRNA-dihydrouridine-synthase-DusB	gnl|CDD|129820	TIGR00737, Probable_tRNA-dihydrouridine_synthase, putative TIM-barrel protein, nifR3 family. This model represents one branch of COG0042 (Predicted TIM-barrel enzymes, possibly dehydrogenases, nifR3 family). This branch includes NifR3 itself, from Rhodobacter capsulatus. It excludes a broadly distributed but more sparsely populated subfamily that contains sll0926 from Synechocystis PCC6803, HI0634 from Haemophilus influenzae, and BB0225 from Borrelia burgdorferi. It also excludes a shorter and more distant archaeal subfamily.The function of nifR3, a member of this family, is unknown, but it is found in an operon with nitrogen-sensing two component regulators in Rhodobacter capsulatus.Members of this family show a distant relationship to alpha/beta (TIM) barrel enzymes such as dihydroorotate dehydrogenase and glycolate oxidase. [Unknown function, General].	2.1567e-155
NZ_CP046703.1|WP_114081924.1|4940938_4942171_-|glycosyltransferase-family-4-protein	gnl|CDD|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	1.00842e-43
NZ_CP046703.1|WP_114081922.1|4939727_4939940_+|thiamine-biosynthesis-protein-ThiS	gnl|CDD|180978	PRK07440, PRK07440, thiamine biosynthesis protein ThiS.	1.12974e-44
NZ_CP046703.1|WP_114081923.1|4939936_4940818_-|class-D-beta-lactamase	gnl|CDD|225322	COG2602, COG2602, Beta-lactamase class D [Defense mechanisms].	2.62777e-90
NZ_CP046703.1|WP_114081918.1|4933743_4934601_-|acyl-CoA-desaturase	gnl|CDD|224316	COG1398, OLE1, Fatty-acid desaturase [Lipid metabolism].	3.21625e-102
NZ_CP046703.1|WP_114081925.1|4943054_4944038_+|DUF1517-domain-containing-protein	gnl|CDD|226808	COG4371, COG4371, Predicted membrane protein [Function unknown].	5.09451e-134
NZ_CP046703.1|WP_114081920.1|4936085_4937987_-|DUF1565-domain-containing-protein	gnl|CDD|284923	pfam07602, DUF1565, Protein of unknown function (DUF1565). These proteins share a region of homology in their N termini, and are found in several phylogenetically diverse bacteria and in the archaeon Methanosarcina acetivorans. Some of these proteins also contain characterized domains such as pfam00395 and pfam03422.	1.50742e-44
NZ_CP046703.1|WP_114081919.1|4934774_4936004_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.25025e-12
NZ_CP046703.1|WP_114081912.1|4925152_4926208_-|permease	gnl|CDD|223773	COG0701, COG0701, Predicted permeases [General function prediction only].	1.8015e-75
NZ_CP046703.1|WP_114081921.1|4938483_4939599_+|thiamine-phosphate-synthase	gnl|CDD|235054	PRK02615, PRK02615, thiamine phosphate synthase.	0
NZ_CP046703.1|WP_114081916.1|4929384_4930476_+|alanine-dehydrogenase	gnl|CDD|240630	cd05305, L-AlaDH, Alanine dehydrogenase NAD-binding and catalytic domains. Alanine dehydrogenase (L-AlaDH) catalyzes the NAD-dependent conversion of pyruvate to L-alanine via reductive amination. Like formate dehydrogenase and related enzymes, L-AlaDH is comprised of 2 domains connected by a long alpha helical stretch, each resembling a Rossmann fold NAD-binding domain. The NAD-binding domain is inserted within the linear sequence of the more divergent catalytic domain. Ligand binding and active site residues are found in the cleft between the subdomains. L-AlaDH is typically hexameric and is critical in carbon and nitrogen metabolism in micro-organisms.	0
NZ_CP046703.1|WP_114081907.1|4917932_4918715_+|sulfite-exporter-TauE/SafE-family-protein	gnl|CDD|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	2.01377e-31
NZ_CP046703.1|WP_167756019.1|4919060_4919591_-|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.83082e-20
NZ_CP046703.1|WP_114081911.1|4924325_4925099_-|TIGR03943-family-protein	gnl|CDD|274870	TIGR03943, TIGR03943, TIGR03943 family protein. Members of this occur in gene pairs with members of pfam03773. The N-terminal region contains several predicted transmembrane helix regions while the few invariant residues (G, CxxD, and W) occur in the C-terminal region.	1.89643e-91
NZ_CP046703.1|WP_114081914.1|4926867_4927875_-|WD40-repeat-domain-containing-protein	gnl|CDD|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	2.67012e-93

Protein sequences

>NZ_CP046703.1|WP_114081916.1|4929384_4930476_+|alanine-dehydrogenase
MEIGVPKENKDQEFRVGLSPSSVRVLRENGHSIFVETQAGNGAGFSDDDYRSAGAEIVPTSETAWNRELVVKVKEPLTSEYKFLQKGQILFTYLHLAADRKLTEHLIDCGTTAIAYETVEQPGANKLPLLTPMSVIAGRLAVQFGARFLERQQGGRGLLLGGVPGVKPGNVVILGGGVVGTEAAKIAVGMGAIVQILDVSVERLSYLETLFGSRVELLYSNSAHIEAAVKEADLLIGAVLVLGRRAPTLVSRELVKQMRPGSVIVDVAVDQGGCIETLRATSHTNPVYLEEGVVHYGVPNMPGAVPWTATQALNNSTLPYIVQLANLGIMALEVNPALAKGVNVQNHRLVHPAVQEVFPDLVN
>NZ_CP046703.1|WP_114081915.1|4928796_4928967_-|hypothetical-protein
MTQTQPTIAPKLEEPKFGFNEYAERLNGRAAMIGFALMLVIEYVTNQGVLSWLGLK
>NZ_CP046703.1|WP_012410339.1|4928176_4928470_-|hypothetical-protein
MNAVLPRFLKSTYRKEPLISVLVTMGAIDALIGGLNDSWSLFAFGLGTTGIALAFKLWRFQQRRPLPEEPVVQHYLPSRSSSAPLPMLSVSKKKPPL
>NZ_CP046703.1|WP_114081914.1|4926867_4927875_-|WD40-repeat-domain-containing-protein
MAAVALPVTIWQGFYIHQAHAAVEVTPNSPTTNSFANAQLLYTLRGHNGTVKSLAFSPDSRILASGGAENEGIIRLWNPVNGKKLGDINKAHKSAIESLVISPDGQTLASCSDDNTINLWSLKNFKFSRSFVGHTSNVLSLAVSPDSKVLISGALDGIRLWDLLQQRPLGTLVRFDNLIYTLAISPDGQTLASGDNKGVIKVWSLSTGKLISEFVAHSNVVSAVIFTPDGQTLVSASRDRTVKLWNINTGELVRTLTGHNNWVNAIAINPDGQTLASAGKDGIKVWNLTTGELINTLNGHTDWVSAIAFSPNGKILASGGFDRQIKIWGTPQKRN
>NZ_CP046703.1|WP_114081912.1|4925152_4926208_-|permease
MNQLNNGFTIFLSLLVEAMPFLLIGVLFSSLLLFFVDERKLVEKMPKNPLLGALVGSLIGFLFPVCECGNVPVARRFLIQGVPTPVAIGFLLAAPTINPIVIWSTWTAFRDQPEIVVLRVVFSLAIATIIGFVFSFQKDLNPIIQPAIARYMKFNPPAQPETKRRGKRYQVEQQEAVPNILQSGTYILGGKAGVPLRIDANFVQPTAPISNTNKPLADKLRLVVDNSVQEFRELGGVMILGSAIAAAIQVLAPRELILSLGAGPISSIVVMLILAVVVSICSTVDSFFALSFASTFSSGSLLAFLVFGPMIDIKSVGLMLSIFKPKTVFYLFALAAQLTFVLTLFLNLHVF
>NZ_CP046703.1|WP_114081911.1|4924325_4925099_-|TIGR03943-family-protein
MANKNPKSKIPNLLLPWLDALAITSWGILMLRYWLTNKLNLLIHPNYIWFVVVTGISLIVIGFFKMQELWQRRRRDVTPNGQHISLFPPGWGSVLLLITAILGFIITPQVFASDKALQRGVTTDLLGSTRVKPQAFRATVRPEERSLVDWVRTVNVYPEPDTYTGQKVKVQGFVIHPPDIGKEYLFLARFVLTCCAADAYPVGLPVKLPNNQERYSPDTWLEVEGQMMTENLAGKRQLTIAATSLKKIPQPQNPYSY
>NZ_CP046703.1|WP_114081910.1|4922766_4924266_-|hypothetical-protein
MTKSKTFIQPLDRIAIALMLLLSVLIGLIILQGDVVTARVRDFTWQNQQIGAEDNSFTLTFSRPMETKSVEDNLKIEPPLAGKFSWAGRRMVYTLLTPAPYGTNYKLQLQGAKDKFAQQEGKNRLIQAFTGSFRTRDRVILYIGSNQEEQGRLVLYNLTQEQKRVLTPKDLIAMDFESFPDGEKILFSARASNNEDLLSAQLYTVTTGVSSKSGQEAQPGGKVDLVLDSKDYQNLKFDLSPDGQTIVIQRGNKNNPGDFGLWFMPATSDGSAEKPTPKRLKSQPGGDFMITPDSKAVAVAQGQGAAILPLQGDASKPLDFLPQFGLVQAFSKDGSQAAMVKFNTDYTRDLFLVTNQGVQKQLLKTTGSILSCQFDIASPTLYCLLTQLVSKEQYIEQPYVVAIDLKTGQQKPLLVLPPAQRNVQMSLSADGLGLLFDQVVPQTNPPASLPTNTLKTDDGDVIATSSLWLMPLLPIADAATVEIRPEQLPLAGFRPRWLP
>NZ_CP046703.1|WP_114081909.1|4920654_4922430_+|HAMP-domain-containing-histidine-kinase
MYDLQMFTMRDMSECGLALRSLGKKANSMEEVGNHIVQYLYNNLIDLKSGERSCALVRFFKTHSYGELPPKLQEYTHSFVSNDVLENNLKCLTLLSTAGQQPEWNSRHKSEGHKVIPLFSKEMIAQIPMIFQLIQQLGLNLDVVVRPDLNLLTDLEQRMYNVFYVPDALGSSYIPSQTSFVIPYNIKSVVGVGGLLPSGNIFIIIMFLKVAIPRISVDLLRPLALNVKMTILPFENEKTFTEQEQHLVGDNISTTTDDETFQYLNSQITTLNQLLDVSEQSTISQSDRLEQTNASLQETLKKLQSTQIQLVHNEKMSSLGKLVAGIAHEINNPVNFIYGNLSYAKEYTHSILKIIQKYQNYYPDPPEEIKKLVKENDLDFLIRDLTRTFNSMTVGTERITEIVSSLRNFSRLDEAEIKQVYIHEGIDSTLMILKHFLQATDKTPEIEVVKQYSQLPLIECYPAQINQAFMNIITNAIDALQDSGKSWFRANNQLEKPNFLLPVIRISTEVIDPEWVAITIADNGCGMNEKVRARLFDPFFTTKPVGKGTGLGLSISYQIIVEQHRGKIGCISVPEQGTEFVIKIPVKTKNV
>NZ_CP046703.1|WP_167756019.1|4919060_4919591_-|response-regulator-transcription-factor
MTAYSDKSTVERATVTFTCGYILKPISQQNLYVAIQTALNIIRNKQAELVLSKAYEELKIKVKNYTTKLALVNDELKLEITRPHQLESELSTKKGRIFTNNKPSSLLTSRQLEILKLIAEGLSTKEIAELLSISTKTVEAHRVHLMKRLNIYDVVGLVRYAISIKLVNFDIPNHSD
>NZ_CP046703.1|WP_114081907.1|4917932_4918715_+|sulfite-exporter-TauE/SafE-family-protein
MIDFSWLILVTGGLISGVIAGLLGIGGGIITIPLLVTLGYTPVQAIATSSLAIVITSISGSLQNWSMGYFDFKRVMYLGIPAFLTTGIGVYFANKIPSYIILFTFGIILLVNIYLIELRKELALNEKENTAPVFNPLVSKIGTGGAAGILAGLFGLGGGTIMVPLQMLLLGEEIKVAIQTSLGVIVITALAACTGHTLEGNILFAQGLVLGCGGLLGVQMSTRTLPKLPDSTVSLVLRIFLGILSIYLFWEAWINYRHII
>NZ_CP046703.1|WP_114081917.1|4931656_4932712_-|tRNA-dihydrouridine-synthase-DusB
MISLSPILQARLSQPLKIGSFEVKSRVLQSPLSGVTDMVFRRLVRRYAPDSMMYTEMVNATGLHYVKQLPKIMEVDPNERPISVQLFDCRPDFLAEAAIKAVAEGADTVDINMGCPVNKITKNGGGSSLLRQPEVAEAIVREVVKAVDVPVTVKTRIGWNDNEITILDFAKRMEDAGAQMITVHGRTRAQGYNGNARWEWITRVKEVLSIPVIGNGDIFSVEAAVKCLEQTGADGVMCSRGTLGYPFLVGEIDHFLKTGEILPTPTPIQRLECARDHLQALWEYKGDRGVRQARKHMTWYAKGFVGAAELRGQLSLVEKVDQGLGMLDQAIEKLANGYELEEEAEGSLVML
>NZ_CP046703.1|WP_114082006.1|4932788_4933622_-|Rpn-family-recombination-promoting-nuclease/putative-transposase
MKTDSIFYRLFQELPEIFFELIGNLPQTAEGYKFSSIEIKQTTFRIDGVFLPTQGQENPIYFVEVQFQTDAEIYSRLISEICLYLRQNKPKNSWRGVVIYPNRSLDIADINNYSEFFTSNRVTRIYLNELGETASLPVGIATMKLVVDEEETAITSARQLIERTQQEINIEPQRRQLLELIETILVYKFPTMSPEEIEGMFGLSDLKQTRVYQEGKQEGKQEGKQEGKQEGAREEKFRMIPLLLRLGLSFEEMAKELGLSLEEVQQEIQKQPPSQDT
>NZ_CP046703.1|WP_114081918.1|4933743_4934601_-|acyl-CoA-desaturase
MTANFGAIAPERGNSPRLSWTNVVFFATFHALALMSPWFFSWPALGLLVFLHWLFGSIGICLGYHRLLSHKSFQVPKWLEYAIALIGALALQGGPIFWVGGHRQHHAHTEDINLDPYSAQRGFWWSHILWIFYPRPEFFDYDTYKKYAPDLARQPFYCWLDRYFLLLQIPFALLLYGLGGWPFVFYGVFLRCVLLWHSTWFVNSASHLWGYRTFDANDGARNLWWVSIVTYGEGWHNNHHTYPHMAKSGLSWWEIDVTWWSIRVLQTLGLAKKVVSSPPQGATHG
>NZ_CP046703.1|WP_114081919.1|4934774_4936004_+|TetR/AcrR-family-transcriptional-regulator
MSSHLVSTRQRLIQAALELFSAQGVSATTTRQIAEKAEVNEVTLFRNFGNKHGLLLAVLEESAAFKDLGESLVRRATPPGNVYQALKDYASDSLHALERVPEFVRSVVGEADQFPAENRRALGRGVTEANRYVAQYLATVIQQGHLNTYLPAEKLASLLNGMILGYAVIEFTSEFHELWEDRNDFLENLVELFLHGAMSSSAESAINCLQGGFTTTEVADLPASLVHEILQQARKSGVRDYALAYVLFGAGLSATEIISLERSHQIYDPQGHFLQITIPGCIRQVPVNQWILGKRYGSFTNNPLIKWLKSRKDAQTAMFLNETGKPMTESELETRWQVWSEGLLTPQGQTPAIAQAQQTWRVEMLMRGITLENLIILTGCDRIQLQPYVRRAKEKAALEQATRLDHKPG
>NZ_CP046703.1|WP_114081920.1|4936085_4937987_-|DUF1565-domain-containing-protein
MIHYRVFPKYRRVNIMLAKLKFLESARLLFFSLSVLSFTVSMGATSMTFLDNALAKPAEGIAQIPSTPNSAPLGETKNSQANVLFVNSNGGNDSAGNGSESAPVKTITHALRLANPNTVIMLSTGTYSAETGEEFPLMLKPGVSIQGNPSNQGKDIIIQGGGDYLSRSFGGQNVTIVGANQALLTGVTVTNSNRRGYGLWIESSDPVIAENTFTGSTQDGISVSGNAAPTISKNYFDRNGANGMTIAGNSSPQVKENVFHQTGFGINIAQNAAPIVIGNQIQNNRSGIVVQAKAHPILRNNIIQDNKEDGLVAIAQAMPDLGSASEPGGNQFQNNARYDINASAAKQMISAGGNNLVSDRISGKVDINGTIALAAQNSQSTPNNVLQEIPPTGEITFSAPGISETTNSQNSNSISANNPVSAKLNTQLLPLVPAKVPLSTPISNQQQPTSKVAGFPTPSSLSARQIPTNTQIATSSPAQPPNTPQLNYVRIDPNTIEFTAPEYPSNSVTSTRNQTQQPLPIREATAPNASALLPLPDNNIPISNTGNMQTSSASIPYASKSATQFGIRYRVVVPLLTDRDQDLVRSLAPGAFPTVWEGQRVMQAGVFSSEYNAKEMLKTLSSNGLRAIMEPLN
>NZ_CP046703.1|WP_114081921.1|4938483_4939599_+|thiamine-phosphate-synthase
MVTKRYDNSHFDESTNGVVVMVEPYSQKEQVQQVVYRILDANLDRAREGLRIIEEWCRFGLNNAQLALECKRLRQELAKWHTPELRAARDTPGDPGTELTHPQEEERASIKSVLQANFCRVEEALRVLEEYSKLYQPNIAKACKQMRYQVYTLESNLMGHQRHQLLWRSHLYLVTSPNENLLNNVEAALKGGLTLLQYRDKTTDDSLRLEQARKLRQLCHIYGALFIVNDRVDLALAVDADGVHLGQQDMPIAIARELLGSQRLIGLSTTNKEEMQGAIAEGVDYIGVGPVYETPTKVGKAATGLEYVSYAAKNCSIPWFAIGGIDANNINDVIDAGAKRVAVVRSLMQAEQPTLVTQYLLSQLNRIKPEL
>NZ_CP046703.1|WP_114081922.1|4939727_4939940_+|thiamine-biosynthesis-protein-ThiS
MSNEITVQVNGETHSCSFQISLPDLIQQLGFNPRLVAVEYNGEILHRQFWPQTKLQPGDRLEVVTIVGGG
>NZ_CP046703.1|WP_114081923.1|4939936_4940818_-|class-D-beta-lactamase
MWQSLRHYRRQAVIFTILGCVAVLSVISFRTMPILAQPASTSSERPAIKAPNFGRHFQEFGREGSILIYDSKNNRTYEHNPKRNATAIAPASTFKIFNALVALETGVVPDDVAVLTWDGIHRDIDAWNHDTNLRQAFKDSTVWFYQVLARKAGYERMQQFINKVGYGNRQIGTAADIDRFWLEQQLLQITPQEQIKFLQRLYQGDLPFSQRTINLVKDIMVREQTPDYTLRGKTGWLTSTKPQVGWFVGYLEQNKNVYFFATTLDMYKPEDAPVRIEITRRSLKDLGLLAHIN
>NZ_CP046703.1|WP_114081924.1|4940938_4942171_-|glycosyltransferase-family-4-protein
MEHISQLTAEIRDKAAYPDILVISRIFLPKEAVIGEYMYNRCLQDPERVIVLAASCSGDKVFDEGQQFPVYRWFYPRYWRSGFVGNILKPFVNIVCSFVLAIKLYFRYHYRYIEWGHGYDFPSLLLLSYLLPIRFFIYLHGNDFLCTLHNPVLRSLFKLTLHRAEGIVCNSSYTQDYLRTALRLDTPTYVINPIIRPEKFGNNVGSPSSLDDLRVRVRQAYNIPDSAIAILSIGRLVKHKAFDRVIDNIPLLLTFGVDVHYIICGEGPSESELKSLVHRLRVDKRVHFAGYLPERELAGYYAACDIFAMLTLLDTKPNNMEGFGMVYLEASYFGKPIIAPRLGGVLDTVQHEENGILVNPNSGYEVFQAFNRLCKDQQLREQLGRKGKELAKRRTLHRSLYKSEGKNAIL
>NZ_CP046703.1|WP_114081925.1|4943054_4944038_+|DUF1517-domain-containing-protein
MRKKLQQISKPLLKTFLALGLVLTLVLSHADGALAARSGGRIGGGSFRAPSSRTYTPRTYAPPGGGGYYPGGGFGGGFGFPFLLPFWGIGGGFGGLFSILIFFAIANFLLQTFRRVSGGETPEADYSSNSPVSVTRLQVGLLAQARELQNELNHIAETADTNTPEGRAEILQEASLALLRHPEYFVYAGGGTQQASLNSAESQFNRLSLAERSKFSEETLSNVNNQLKAALAKEALPPAGELDNPTRLFTEGPGEYIIVTLLAATLGKFDIPTAINSADDLRQALRQIGSIPSEKLLAIEVLWTPQAENDTLTSDDVLANYPDLRLV

Crispr_ID: NZ_CP046703_10

• CRISPR_ID: NZ_CP046703_10
• CRISPR_location: 5414739-5414917
• CRISPR_type: Orphan
• Repeat_type: I-D,II-B
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP046703_10

Consensus_repeat	Method
GTTTCAATCCCTAATAGGGATTTTATTTGATTGCAAT	CRISPRCasFinder

spacers of NZ_CP046703_10

>10.1|5414776|33|NZ_CP046703|CRISPRCasFinder
TCAAGGCTAAATGTTTGCTCACTGCTTTAAACA
>10.2|5414846|35|NZ_CP046703|CRISPRCasFinder
CTTAGCTAAACAATATTTAGATGAAAAAGCCAATG

CRISPR arrays and Neighbor proteins around NZ_CP046703_10

CRISPR arrays

The CRISPR arrays of NZ_CP046703_10

>merge|NZ_CP046703|10|5414739-5414917|CRISPRCasFinder
CAAACATCCTCTAATAGGGATTTTATTTGATTGCAATTCAAGGCTAAATGTTTGCTCACTGCTTTAAACAGTTTCAATCCCTAATAGGGATTTTATTTGATTGCAATCTTAGCTAAACAATATTTAGATGAAAAAGCCAATGGTTTCAATCCCTAATAGGGATTTTATTTGATTGCAAT

>NZ_CP046703|10|10|5414739-5414917|CRISPRCasFinder
CAAACATCCTCTAATAGGGATTTTATTTGATTGCAAT	TCAAGGCTAAATGTTTGCTCACTGCTTTAAACA
GTTTCAATCCCTAATAGGGATTTTATTTGATTGCAAT	CTTAGCTAAACAATATTTAGATGAAAAAGCCAATG
GTTTCAATCCCTAATAGGGATTTTATTTGATTGCAAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046703.1|WP_114083396.1|5421532_5421943_-|response-regulator	unknown	unknown	gnl|CDD|381118
NZ_CP046703.1|WP_114083414.1|5410547_5413328_-|insulinase-family-protein	unknown	unknown	gnl|CDD|223685
NZ_CP046703.1|WP_114083384.1|5401603_5402995_+|UDP-glucose/GDP-mannose-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|223936
NZ_CP046703.1|WP_114083390.1|5408467_5409214_+|hypothetical-protein	unknown	unknown	gnl|CDD|375603
NZ_CP046703.1|WP_114083388.1|5405403_5406654_-|competence/damage-inducible-protein-A	unknown	unknown	gnl|CDD|234789
NZ_CP046703.1|WP_114083399.1|5423859_5424585_-|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223736
NZ_CP046703.1|WP_114083397.1|5422099_5422831_-|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223736
NZ_CP046703.1|WP_114083394.1|5419161_5420292_+|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)	unknown	unknown	gnl|CDD|272978
NZ_CP046703.1|WP_114083395.1|5420547_5421219_-|peptidoglycan-binding-protein	unknown	unknown	gnl|CDD|213747
NZ_CP046703.1|WP_114083386.1|5404691_5405108_-|PIN-domain-containing-protein	unknown	unknown	gnl|CDD|350263
NZ_CP046703.1|WP_114083392.1|5415534_5416302_-|circadian-clock-protein-KaiB	unknown	unknown	gnl|CDD|239276
NZ_CP046703.1|WP_159402548.1|5424973_5425144_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114083389.1|5406774_5408058_-|serine-hydroxymethyltransferase	unknown	unknown	gnl|CDD|234571
NZ_CP046703.1|WP_114083385.1|5403331_5404204_-|DUF2993-domain-containing-protein	unknown	unknown	gnl|CDD|378597
NZ_CP046703.1|WP_114083391.1|5409223_5409847_+|DUF4231-domain-containing-protein	unknown	unknown	gnl|CDD|379418
NZ_CP046703.1|WP_114083387.1|5405094_5405355_-|CopG-family-transcriptional-regulator	unknown	unknown	unknown
NZ_CP046703.1|WP_012409057.1|5418534_5418909_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114083398.1|5422911_5423658_-|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223736
NZ_CP046703.1|WP_114083393.1|5416521_5417805_-|type-IV-pilus-twitching-motility-protein-PilT	unknown	unknown	gnl|CDD|225364
NZ_CP046703.1|WP_114083383.1|5400504_5401455_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|187541

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046703.1|WP_114083396.1|5421532_5421943_-|response-regulator	gnl|CDD|381118	cd17580, REC_2_DhkD-like, second phosphoacceptor receiver (REC) domain of Dictyostelium discoideum hybrid signal transduction histidine kinase D and similar domains. Dictyostelium discoideum hybrid signal transduction histidine kinase D (DhkD) is a large protein that contains two histidine kinase (HK) and two REC domains on the intracellular side of a single pass transmembrane domain, and extracellular PAS and PAC domains that likely are involved in ligand binding. This model represents the second REC domain and similar domains. DhkD activates the cAMP phosphodiesterase RegA to ensure proper prestalk and prespore patterning, tip formation, and the vertical elongation of the mound into a finger, in Dictyostelium discoideum. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	3.61818e-36
NZ_CP046703.1|WP_114083414.1|5410547_5413328_-|insulinase-family-protein	gnl|CDD|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	7.83814e-93
NZ_CP046703.1|WP_114083384.1|5401603_5402995_+|UDP-glucose/GDP-mannose-dehydrogenase-family-protein	gnl|CDD|223936	COG1004, Ugd, Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane].	0
NZ_CP046703.1|WP_114083390.1|5408467_5409214_+|hypothetical-protein	gnl|CDD|375603	pfam18171, LSDAT_prok, SLOG in TRPM, prokaryote. Family in the SLOG superfamily, fused to or operonically associating with SLATT domain in diverse prokaryotes. Predicted to function as ligand sensor in conjunction with the SLATT transmembrane domain.	1.51245e-80
NZ_CP046703.1|WP_114083388.1|5405403_5406654_-|competence/damage-inducible-protein-A	gnl|CDD|234789	PRK00549, PRK00549, competence damage-inducible protein A; Provisional.	0
NZ_CP046703.1|WP_114083397.1|5422099_5422831_-|Crp/Fnr-family-transcriptional-regulator	gnl|CDD|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	1.99769e-25
NZ_CP046703.1|WP_114083395.1|5420547_5421219_-|peptidoglycan-binding-protein	gnl|CDD|213747	TIGR02869, Spore_cortex-lytic_enzyme, spore cortex-lytic enzyme. Members of this protein family are the spore cortex-lytic enzyme SleB from Bacillus subtilis and other Gram-positive, endospore-forming bacterial species. This protein is stored in an inactive form in the spore and activated during germination. [Cellular processes, Sporulation and germination].	4.00913e-12
NZ_CP046703.1|WP_114083386.1|5404691_5405108_-|PIN-domain-containing-protein	gnl|CDD|350263	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins. Mycobacterium tuberculosis VapC26 cleaves 23S rRNA in the Sarcin-Ricin Loop, it is inhibited by the cognate VapB26 antitoxin. This subfamily belongs to the VapC (virulence-associated protein C)-like nuclease family of the PIN domain-like superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	2.46357e-42
NZ_CP046703.1|WP_114083392.1|5415534_5416302_-|circadian-clock-protein-KaiB	gnl|CDD|239276	cd02978, KaiB_like, KaiB-like family; composed of the circadian clock proteins, KaiB and the N-terminal KaiB-like sensory domain of SasA. KaiB is an essential protein in maintaining circadian rhythm. It was originally discovered from the cyanobacterium Synechococcus as part of the circadian clock gene cluster, kaiABC. KaiB attenuates KaiA-enhanced KaiC autokinase activity by interacting with KaiA-KaiC complexes in a circadian fashion. KaiB is membrane-associated as well as cytosolic. The amount of membrane-associated protein peaks in the evening (at circadian time (CT) 12-16) while the cytosolic form peaks later (at CT 20). The rhythmic localization of KaiB may function in regulating the formation of Kai complexes. SasA is a sensory histidine kinase which associates with KaiC. Although it is not an essential oscillator component, it is important in enhancing kaiABC expression and is important in metabolic growth control under day/night cycle conditions. SasA contains an N-terminal sensory domain with a TRX fold which is involved in the SasA-KaiC interaction. This domain shows high sequence similarity with KaiB. However, the KaiB structure does not show a classical TRX fold. The N-terminal half of KaiB shares the same beta-alpha-beta topology as TRX, but the topology of its C-terminal half diverges.	2.08703e-30
NZ_CP046703.1|WP_114083389.1|5406774_5408058_-|serine-hydroxymethyltransferase	gnl|CDD|234571	PRK00011, glyA, serine hydroxymethyltransferase; Reviewed.	0
NZ_CP046703.1|WP_114083385.1|5403331_5404204_-|DUF2993-domain-containing-protein	gnl|CDD|378597	pfam11209, DUF2993, Protein of unknown function (DUF2993). This family of proteins with unknown function appears to be restricted to Cyanobacteria.	2.1781e-20
NZ_CP046703.1|WP_114083391.1|5409223_5409847_+|DUF4231-domain-containing-protein	gnl|CDD|379418	pfam14015, DUF4231, Protein of unknown function (DUF4231). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea, eukaryotes and viruses. Proteins in this family are typically between 148 and 288 amino acids in length.	1.22052e-36
NZ_CP046703.1|WP_114083394.1|5419161_5420292_+|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)	gnl|CDD|272978	TIGR00236, UDP-N-acetylglucosamine_2-epimerase, UDP-N-acetylglucosamine 2-epimerase. This cytosolic enzyme converts UDP-N-acetyl-D-glucosamine to UDP-N-acetyl-D-mannosamine. In E. coli, this is the first step in the pathway of enterobacterial common antigen biosynthesis.Members of this orthology group have many gene symbols, often reflecting the overall activity of the pathway and/or operon that includes it. Symbols include epsC (exopolysaccharide C) in Burkholderia solanacerum, cap8P (type 8 capsule P) in Staphylococcus aureus, and nfrC in an older designation based on the effects of deletion on phage N4 adsorption. Epimerase activity was also demonstrated in a bifunctional rat enzyme, for which the N-terminal domain appears to be orthologous. The set of proteins found above the suggested cutoff includes E. coli WecB in one of two deeply branched clusters and the rat UDP-N-acetylglucosamine 2-epimerase domain in the other. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	0
NZ_CP046703.1|WP_114083399.1|5423859_5424585_-|Crp/Fnr-family-transcriptional-regulator	gnl|CDD|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	5.53342e-23
NZ_CP046703.1|WP_114083398.1|5422911_5423658_-|Crp/Fnr-family-transcriptional-regulator	gnl|CDD|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	5.84874e-27
NZ_CP046703.1|WP_114083393.1|5416521_5417805_-|type-IV-pilus-twitching-motility-protein-PilT	gnl|CDD|225364	COG2805, PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion].	0
NZ_CP046703.1|WP_114083383.1|5400504_5401455_+|SDR-family-oxidoreductase	gnl|CDD|187541	cd05230, UGD_SDR_e, UDP-glucuronate decarboxylase (UGD) and related proteins, extended (e) SDRs. UGD catalyzes the formation of UDP-xylose from UDP-glucuronate; it is an extended-SDR, and has the characteristic glycine-rich NAD-binding pattern, TGXXGXXG, and active site tetrad. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	0

Protein sequences

>NZ_CP046703.1|WP_114083414.1|5410547_5413328_-|insulinase-family-protein
MKLRSYMFLGFFLSLLLSLLPFSSNFINAATPTVVAPVSADSFTQGVKKTVLDNGLTVLTKEVHTAPVVSVQVWYKVGSRNEVKGENGISHQLEHLMFKGTTARPVQFGRLFSALGSQFNAFTSYDETAYFGTVQRDRLEALLTLEADRMENSLIGPEQLKSEKRVVISELQGYENSPGYRLSRAVMRDAFPNRAYGLSVGGTKADVEKFTVEQVRNYYQTYYSPDNATLVITGDFATEPVLKVVKETYGKLTKRGNEEKRTRENVAPSSPVAPTTKKAPIVLKQPGSAALLQAVYPLPDIKHPDVPAIDVMDAILTGGRSSRLYQALVESGLASSVSGGAAELIEPGWYEINATAAPGQELSKIAQVLQESLGKLQQQPVTTEELNRAKTQLQASYILGNQDITSQASQLGYNQTIAGDYHFIEQYLAAIAKVTPAQVQKVAKTYLNPAKQTIGFFEPTQPDGKPGTSSAGSGRTVENFSPGKPVDPAELAKYLPPATSATDSAKQSLPEEFTLNNGLRVLLLRDRSLPTINLSGQIDAGTEFDGNQKAGLANLTAANLMNGTQTKNALTLAKTLEDLGADLSFSASREGVNVSGEGLSKNLPILIQTLADVLENATFPADQLELSRQRALTSLKVQLDDPRGLGRQVFQQAIYPENHPFHSFPTFESLKSISRDDLLGFYQKYYRPDSTTIAIVGDFDPVKVKTLLNQAFGTWQATGKPPVLKISSVPLPQTSTRLNKIIPGKAEAVTYIGYNGISRKDPRYYAALILNQILGGDTLSSRLGTEVRDRLGLTYGIYSGFAAGINPGPFLIQMQTAPGDTQKAIASTLALLKQLREQGVTEAEFNTAKRSLTNSYPVDLANPSNVSSIILDNAVLGLSRSEIRDFPQRIQAVTMAQMQQAIEDLIKPENLVIVTAGPGEIVPKGG
>NZ_CP046703.1|WP_114083391.1|5409223_5409847_+|DUF4231-domain-containing-protein
MAKKDSYQEFLKEDFNKLFEGMNLGDGQRHFLRSRWLDQVLWMEGKANLSRDRHYLLRITTIIGGVILPALVSLNINTTSTLQVNERSRNIIIWSTFGLSQIVAISAAIEEFFHYGERWRHYRRTVESLKTQGWQFSQLTGPYRDYTSHQQAFNLFAGNVEDVIQRDVEIYSTQVIQEKKEEKQSQENYILMPNAKITNLEEKKEEK
>NZ_CP046703.1|WP_114083390.1|5408467_5409214_+|hypothetical-protein
MKNPLKLTFDRGQTALAIRVDRQAELPDAIEQIGLGGSRSILVVVGGASKISEADFLRIKRLFTEVLAPIAESLGAYVVDGGTDAGVMQLMGEARSQIGAKFALIGVTPENKVALPDQQEPGSDLTPLEPNHTHFVLVPGDNWGDESPWISDVATMLANNAPSVTVLLNGGEITFDDAFYSVNTGRLVVVIAGSGRTADILADALRGEGTDERAKKLAKSGILQYVNLIDIENGVKNLGQIIKDLLSN
>NZ_CP046703.1|WP_114083389.1|5406774_5408058_-|serine-hydroxymethyltransferase
MTRTNSDFLSSTDPAIAELINDELQRQRDHLELIASENFTSAAVLAAQGSVLTNKYAEGLPGKRYYGGCEYVDKIEQLAINRAKQIFGAAHANVQPHSGAQANFAVFLSLLEPGDKIMGMDLSHGGHLTHGSPVNVSGKWFQVSHYGVSQQTEQLDYDQIRELALRERPKLLICGYSAYPRIIDFEKFRSIADEVGAYLLADIAHIAGLVASGLHPDPIPHCHVVTTTTHKTLRGPRGGLILTSDAELGKKLDKSVFPGTQGGPLEHVIAGKAVAFGEALKPEFKTYSAQVIENARALAEQLQNRGLKLVSDGTDNHLLLVDLRSVNLTGKQADKLVSTVNITANKNTIPFDPQSPFVTSGLRLGSPAMTTRGLGVAEFTEIANIISDRLLSPDSDVVTQDCRQRVAALCDRFPLYPHLEIPVPALA
>NZ_CP046703.1|WP_114083388.1|5405403_5406654_-|competence/damage-inducible-protein-A
MSAEIICVGTELLLGDILNGNAQYLAQQLAQLGIPHYYQTVVGDNPERLKQVIEIAISRAQILIFTGGLGPTPDDLTCETIADFFKTPLVENPEIIEDITQKFAQRGRVMSPSNRKQALIPQGAEILPNPTGTAPGIIWQPRPEITIFTFPGVPSEMYPMWEETAVPFLKSQGWGKEIIYSRSLKFWGIGESALAEKVSSYLKLPNPTVAPYAGKGEVRLRVSAKATSEAAAEELIAPIEKQLKEIAGLDFYGVNNDTLASVVGELLRASKETLSVAESCTGGGLGQMLTEISGSSDYFWGGVISYDNSVKVKLLGVNQEDLDKFGAVSATVAEQMAIGVKTRLATTWGLSITGIAGPTGGTDTKPVGLVYVGLAGPKDEVTSFEYQFGTVRGRALIRHVSANAALDNLRRKLLTR
>NZ_CP046703.1|WP_114083387.1|5405094_5405355_-|CopG-family-transcriptional-regulator
MRINARLDDEYADKLAFIQQQTNQAVTDVIKSAIELYYQQLQQEQKNPFSMLTQTGFIGCGESHPDLSVNYKSILRDGLKAKYDYR
>NZ_CP046703.1|WP_114083386.1|5404691_5405108_-|PIN-domain-containing-protein
MIIVDTGFWLALANRNDSYHTQAITVLANVNEPLITTWPVVTKTCYLLLTKMGNHAQVSFINNLFLGAFTVFDLQPHHAKRICELMEKYANLPMDLADASLVVLAEHLGHGRIFSIDFRDFNAYRWKNQYPFENLMVC
>NZ_CP046703.1|WP_114083385.1|5403331_5404204_-|DUF2993-domain-containing-protein
MNHGIACCILHDLLQKYKELLETQNHMFGGLTGLQDPKGTDWGERMLNTVASQTIRHLFTQSESVEVFVRCYPSSKLLQGSIDSFKMSGRGLVIRRDFAVEEMSFETDAVAIDFGSVLKGKLSLKQPTQAIAQVILSEAGINQAFNAELVKKRLLNLTVPSLTELSGGEPVSFTDVQVQLLPENRLQVVAKADLNNGELVPLSMILTVGIERRRRVSFKDPKIELDQVPESQREISQTLSVALVEILDNMVDLDRFDLDGVKMRLNRLETEGQKLIFSGYAEIERIPSSS
>NZ_CP046703.1|WP_114083384.1|5401603_5402995_+|UDP-glucose/GDP-mannose-dehydrogenase-family-protein
MRVCVIGTGYVGLVTGACLAHIGHDVICVDNNEEKVKLMKSGQSPIFEPGLSEIMQSAIQTQKIHFTSDLAAGVSHGEILFIAVGTPPLPTGESDTRYVEAVARGIGENLNGGYKVIVNKSTVPIGSGDWVRMLVLDGVAERQKTLIPAGGVPSDQKLPEFVAEFDVVSNPEFLREGSAVHDTFNPDRIVLGGNSQRAVALMQQLYAPIVERKYAEDQSLPPVPILATDLSSAEMIKYAANAFLATKISFINEVANICDRVGADVTQVAKGIGLDSRIGNKFLQAGIGWGGSCFPKDVSALIHTADDYGYEAQLLKSAVSVNERQRLIALEKLQQVLKILKGKTVGLLGLTFKPDTDDLRDAPALILIEQLNRLGAKVKAYDPIISQTGMRHGLSGVLVETDAERLADGCDALVLVTEWQQFSTLDYVKMAKLMAHPVIIDGRNFLDPETLIRAGFQYVGVGR
>NZ_CP046703.1|WP_114083383.1|5400504_5401455_+|SDR-family-oxidoreductase
MRILVTGGAGFIGSHLIDRLMNEGHELICLDNFYTGHKRNILKWLGHPYFELIRHDITEPIRLEVDQIYHLACPASPVHYQYNPVKTVKTNVMGTLNMLGLAKRVKARFFLASTSEVYGDPEVHPQTEEYRGSVNPIGIRSCYDEGKRIAETLAFDYYRQNKVDIRVVRIFNTYGPRMLENDGRVVSNFIVQALRGNPLTVYGDGSQTRSFCYVSDLVEGFIRLMNSEYIGPMNLGNPGEYTILQLAQAVQNMINPDAQIKFEPLPSDDPRRRQPDITKAKTWLNWEPTIPLQEGLKLTIEDFRNRIQGDVNNSTN
>NZ_CP046703.1|WP_114083392.1|5415534_5416302_-|circadian-clock-protein-KaiB
MNNLTTNKLSTPQLFKGIALFTPGGDLIYCIDPSKQGRWHLHLCSALQEILDLPEPPHFLVPCYTATIDHWLDPRTQQVRTFAEAYPAVIRHQALLNAIFGTGDLVWQAAPWQEGLCDRMVLTSYRSSFGQLWEDHDLIVRLDLSEPVPKYHQPVIVQKKEVITQGYVLRLFVAGHSSTTERILQNLHELLERSLGHPYTLKVIDVLSHPEQAELNQVSATPTLVKVWPHPIRRIVGELDHVEKILQMLAAKEKF
>NZ_CP046703.1|WP_114083393.1|5416521_5417805_-|type-IV-pilus-twitching-motility-protein-PilT
MTESQSPSNSSPVTERNLPPMPPMPPPPPTFSTQRQMTQTLDMSMDRGSNTPVAGHRPVSPPPIPTSVLPKTSSAGPTLEKLIREAYDQGYSDLHLGVGEVPRFRTRGEIQSWDYPEVDKEAFMNWLREVMSEAEIQRFEEHLEFDGATQYDFARVRINVFGTLRGPAMVLRLIPLKILTMEQLRLPPVFRDICHHHKGLILVTGPTGSGKSTTMAAMVDYINKEMAKHIITIEDPIEFIHQSRKSLVKQREVGMHTRKFDNALKAALREDPDLILVGEMRDKETVNTALKAAQTGHLVMGTLHTNSAVKTIERILNLYSGDEQDAMRVAISESLVAVIAQGLCRTTDGKRAAFHDVLINTEAIKEWIKDGKYDEIGELMKQASFDGMITMNQSLLNLYQDGRITEETALEMSPTPNEMAQFLRGRV
>NZ_CP046703.1|WP_012409057.1|5418534_5418909_+|hypothetical-protein
MVSAESSNLGKTYSLLMIKSFLIWTFTLAVCLLVVGFPLVVLMATVGCLLSIILQSVMPVSAVLLVAGALIMFNVMAVVFAAGVLTIKGVHPSEVKWLSWLHGEADQMQTTVYAACPLTCEIKM
>NZ_CP046703.1|WP_114083394.1|5419161_5420292_+|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)
MTNQKRVCIILGTRPEAIKLAPVIQVFQKSLAFESQVILTGQHREMVEQVMQLFNIKADYDLEIMQVQQSLNDITCRSLQGLEALFKEKKPDLVVVQGDTTTAFAAALAAFYQKIPIGHVEAGLRTDDIFNPYPEEANRRLISQITQLHFAPTPWAVENLHRSGVLGEIHMTGNTVIDALLNVAASQAVCNVPGLDWDSYRVMLATVHRRENWGEPLQAIAEGFLQILDKFPDTAMLLPLHRNPTVRVPLQELLGNHPRIFLTDPLDYGELVGAIGRSHLLLTDSGGLQEEAPSLGKPVLVLRDTTERPEAVVAGTAKLVGTTSENIFASATELLSDPDAYAAMANAINPFGDGHAAERILQIVQNYLGVSSEIST
>NZ_CP046703.1|WP_114083395.1|5420547_5421219_-|peptidoglycan-binding-protein
MEYLAYSQMFIAQEEASGNTKYNLPKSQLNGKEPLKSSNIVIAEKQASANSKSKFNWKKLLKSSAWLALAGVGVLLLAATQIQISSAAYVKTNGSCLRIRTGPSTNYSYVDCVSDGATLPAIERYENGFARLSTGRYVYARWVADRPNKPPVTSKPGGVGGSVILTRGSRGQLVRDVQTALGNLRVDGIYGQETVNQVRSFQASKGLLVDGTVGPETRAALGI
>NZ_CP046703.1|WP_114083396.1|5421532_5421943_-|response-regulator
MSNQSMSFKGLRLLVVDDDPDTRTLLTFLFELEGAEIITAASAGAAIEIMSFFKPDIFISDIYLPDENGCSLLMKVRNLEANRGRKIPAIALTASAFDEDQNRALLAGYDIYRCKPIDLDDLSSTVASLVTLEEYA
>NZ_CP046703.1|WP_114083397.1|5422099_5422831_-|Crp/Fnr-family-transcriptional-regulator
MSENTLKPQVNRLLAALPTSDYERLVPHLKLVSLPTRQVIYEPGEPITEVYFPQNAVVSIVTIMEDGSTVEVGIVSNEGMVGIPVILGGNTTTTKAFVQVAGAGMQMDADVLRTEFKRGGAIQKLLLRYVRAIYTELTQGCACNRLHTLEERLARWLLTVSDRLESDDFPLTQEFIAQMLGVRRSGVTVAASTLSRAGMIRYQRGQISILNREDLEATSCECYQVIQKEFARLLGNQPRRDRR
>NZ_CP046703.1|WP_114083398.1|5422911_5423658_-|Crp/Fnr-family-transcriptional-regulator
MSLNKNLFQQPPNKLLAALPASDYERLLPHLKLVKLPVQQILYEAAEPITQVYFPDKAVVSIVTTMEDGSTAEVGIVSNEGMVGIPVILGDNTTTTTAFVQISGAAMQINADVLRNEFNRGGVIQKLLLCYVQAVYSELAQGAACNRLHTLEERLARWLLTVSDRLESEDFPLTHEFISQMLGVRRSGVTVAASTLSRAGMISYQRGHISILNREDLEATSCECHQVIQNEFARLLGFLPSNRAKKIF
>NZ_CP046703.1|WP_114083399.1|5423859_5424585_-|Crp/Fnr-family-transcriptional-regulator
MSLDKNTFDQPANNLLAVLPFSDYERLVPHLKLVKLSNRQVLYEPGEPITEVYFPNKAVVSIITTMEDGSTVEVGLVSNEGMVGMPVILGDNITTTTAFVQIPDSAMQMDADILRSEFNRGTALQSVLLRYVQGVYTQIAQGSACNRLHKLEGRLARWLLTVSDRLESDEFPLTQEFISQMLGVRRAGVTEAANILSEAGMITYHRGQINILNREALEKTSCECYQIIEDEYIRLLGNKLK
>NZ_CP046703.1|WP_159402548.1|5424973_5425144_+|hypothetical-protein
MKLENFTGIAVAIAELSQITFTHHIDTSIFVSDRSKKSLVAQVLATLSLCRCDRIL

Crispr_ID: NZ_CP046703_11

• CRISPR_ID: NZ_CP046703_11
• CRISPR_location: 5414918-5415168
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NZ_CP046703_11

Consensus_repeat	Method
TGTAGCTACTTACTTATGGATTTTATTTGATTGCAAT	CRT
GTAGCTACTTACTTATGGATTTTATTTGATTGCAAT	PILER-CR

spacers of NZ_CP046703_11

>11.1|5414955|34|NZ_CP046703|CRT
ATAGATTTTGAATTAGTAACAGTTAGTATAAAAT
>11.2|5415026|33|NZ_CP046703|CRT
ATATCCCGGCAATCTTGCGCTAGGTAGCCTGAA
>11.3|5415096|36|NZ_CP046703|CRT
TTAAGTTCAACACCTTCCTTTTTACACTTTCTTAAA
>11.4|5414955|35|NZ_CP046703|PILER-CR
ATAGATTTTGAATTAGTAACAGTTAGTATAAAATT
>11.5|5415026|34|NZ_CP046703|PILER-CR
ATATCCCGGCAATCTTGCGCTAGGTAGCCTGAAT
>11.6|5415096|37|NZ_CP046703|PILER-CR
TTAAGTTCAACACCTTCCTTTTTACACTTTCTTAAAA

CRISPR arrays and Neighbor proteins around NZ_CP046703_11

CRISPR arrays

The CRISPR arrays of NZ_CP046703_11

>merge|NZ_CP046703|11|5414918-5415168|CRT,PILER-CR
TGTAGCTACTTACTTATGGATTTTATTTGATTGCAATATAGATTTTGAATTAGTAACAGTTAGTATAAAATTGTAGCTACTTACTTATGGATTTTATTTGATTGCAATATATCCCGGCAATCTTGCGCTAGGTAGCCTGAATGTAGCTACTTACTTATGGATTTTATTTGATTGCAATTTAAGTTCAACACCTTCCTTTTTACACTTTCTTAAAAGTAGCTACTTACTTATGGATTTTATTTGATTGCAAT

>NZ_CP046703|11|3|5414918-5415168|CRT
TGTAGCTACTTACTTATGGATTTTATTTGATTGCAAT	ATAGATTTTGAATTAGTAACAGTTAGTATAAAAT
TGTAGCTACTTACTTATGGATTTTATTTGATTGCAAT	ATATCCCGGCAATCTTGCGCTAGGTAGCCTGAA
TGTAGCTACTTACTTATGGATTTTATTTGATTGCAAT	TTAAGTTCAACACCTTCCTTTTTACACTTTCTTAAA
AGTAGCTACTTACTTATGGATTTTATTTGATTGCAAT

>NZ_CP046703|11|3|5414919-5415168|PILER-CR
GTAGCTACTTACTTATGGATTTTATTTGATTGCAAT	ATAGATTTTGAATTAGTAACAGTTAGTATAAAATT
GTAGCTACTTACTTATGGATTTTATTTGATTGCAAT	ATATCCCGGCAATCTTGCGCTAGGTAGCCTGAAT
GTAGCTACTTACTTATGGATTTTATTTGATTGCAAT	TTAAGTTCAACACCTTCCTTTTTACACTTTCTTAAAA
GTAGCTACTTACTTATGGATTTTATTTGATTGCAAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046703.1|WP_114083396.1|5421532_5421943_-|response-regulator	unknown	unknown	gnl|CDD|381118
NZ_CP046703.1|WP_114083414.1|5410547_5413328_-|insulinase-family-protein	unknown	unknown	gnl|CDD|223685
NZ_CP046703.1|WP_114083384.1|5401603_5402995_+|UDP-glucose/GDP-mannose-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|223936
NZ_CP046703.1|WP_114083390.1|5408467_5409214_+|hypothetical-protein	unknown	unknown	gnl|CDD|375603
NZ_CP046703.1|WP_114083388.1|5405403_5406654_-|competence/damage-inducible-protein-A	unknown	unknown	gnl|CDD|234789
NZ_CP046703.1|WP_114083399.1|5423859_5424585_-|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223736
NZ_CP046703.1|WP_114083397.1|5422099_5422831_-|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223736
NZ_CP046703.1|WP_114083394.1|5419161_5420292_+|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)	unknown	unknown	gnl|CDD|272978
NZ_CP046703.1|WP_114083395.1|5420547_5421219_-|peptidoglycan-binding-protein	unknown	unknown	gnl|CDD|213747
NZ_CP046703.1|WP_114083386.1|5404691_5405108_-|PIN-domain-containing-protein	unknown	unknown	gnl|CDD|350263
NZ_CP046703.1|WP_114083392.1|5415534_5416302_-|circadian-clock-protein-KaiB	unknown	unknown	gnl|CDD|239276
NZ_CP046703.1|WP_159402548.1|5424973_5425144_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114083389.1|5406774_5408058_-|serine-hydroxymethyltransferase	unknown	unknown	gnl|CDD|234571
NZ_CP046703.1|WP_114083385.1|5403331_5404204_-|DUF2993-domain-containing-protein	unknown	unknown	gnl|CDD|378597
NZ_CP046703.1|WP_114083391.1|5409223_5409847_+|DUF4231-domain-containing-protein	unknown	unknown	gnl|CDD|379418
NZ_CP046703.1|WP_114083387.1|5405094_5405355_-|CopG-family-transcriptional-regulator	unknown	unknown	unknown
NZ_CP046703.1|WP_012409057.1|5418534_5418909_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114083398.1|5422911_5423658_-|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223736
NZ_CP046703.1|WP_114083393.1|5416521_5417805_-|type-IV-pilus-twitching-motility-protein-PilT	unknown	unknown	gnl|CDD|225364
NZ_CP046703.1|WP_114083383.1|5400504_5401455_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|187541

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046703.1|WP_114083396.1|5421532_5421943_-|response-regulator	gnl|CDD|381118	cd17580, REC_2_DhkD-like, second phosphoacceptor receiver (REC) domain of Dictyostelium discoideum hybrid signal transduction histidine kinase D and similar domains. Dictyostelium discoideum hybrid signal transduction histidine kinase D (DhkD) is a large protein that contains two histidine kinase (HK) and two REC domains on the intracellular side of a single pass transmembrane domain, and extracellular PAS and PAC domains that likely are involved in ligand binding. This model represents the second REC domain and similar domains. DhkD activates the cAMP phosphodiesterase RegA to ensure proper prestalk and prespore patterning, tip formation, and the vertical elongation of the mound into a finger, in Dictyostelium discoideum. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	3.61818e-36
NZ_CP046703.1|WP_114083414.1|5410547_5413328_-|insulinase-family-protein	gnl|CDD|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	7.83814e-93
NZ_CP046703.1|WP_114083384.1|5401603_5402995_+|UDP-glucose/GDP-mannose-dehydrogenase-family-protein	gnl|CDD|223936	COG1004, Ugd, Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane].	0
NZ_CP046703.1|WP_114083390.1|5408467_5409214_+|hypothetical-protein	gnl|CDD|375603	pfam18171, LSDAT_prok, SLOG in TRPM, prokaryote. Family in the SLOG superfamily, fused to or operonically associating with SLATT domain in diverse prokaryotes. Predicted to function as ligand sensor in conjunction with the SLATT transmembrane domain.	1.51245e-80
NZ_CP046703.1|WP_114083388.1|5405403_5406654_-|competence/damage-inducible-protein-A	gnl|CDD|234789	PRK00549, PRK00549, competence damage-inducible protein A; Provisional.	0
NZ_CP046703.1|WP_114083397.1|5422099_5422831_-|Crp/Fnr-family-transcriptional-regulator	gnl|CDD|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	1.99769e-25
NZ_CP046703.1|WP_114083395.1|5420547_5421219_-|peptidoglycan-binding-protein	gnl|CDD|213747	TIGR02869, Spore_cortex-lytic_enzyme, spore cortex-lytic enzyme. Members of this protein family are the spore cortex-lytic enzyme SleB from Bacillus subtilis and other Gram-positive, endospore-forming bacterial species. This protein is stored in an inactive form in the spore and activated during germination. [Cellular processes, Sporulation and germination].	4.00913e-12
NZ_CP046703.1|WP_114083386.1|5404691_5405108_-|PIN-domain-containing-protein	gnl|CDD|350263	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins. Mycobacterium tuberculosis VapC26 cleaves 23S rRNA in the Sarcin-Ricin Loop, it is inhibited by the cognate VapB26 antitoxin. This subfamily belongs to the VapC (virulence-associated protein C)-like nuclease family of the PIN domain-like superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	2.46357e-42
NZ_CP046703.1|WP_114083392.1|5415534_5416302_-|circadian-clock-protein-KaiB	gnl|CDD|239276	cd02978, KaiB_like, KaiB-like family; composed of the circadian clock proteins, KaiB and the N-terminal KaiB-like sensory domain of SasA. KaiB is an essential protein in maintaining circadian rhythm. It was originally discovered from the cyanobacterium Synechococcus as part of the circadian clock gene cluster, kaiABC. KaiB attenuates KaiA-enhanced KaiC autokinase activity by interacting with KaiA-KaiC complexes in a circadian fashion. KaiB is membrane-associated as well as cytosolic. The amount of membrane-associated protein peaks in the evening (at circadian time (CT) 12-16) while the cytosolic form peaks later (at CT 20). The rhythmic localization of KaiB may function in regulating the formation of Kai complexes. SasA is a sensory histidine kinase which associates with KaiC. Although it is not an essential oscillator component, it is important in enhancing kaiABC expression and is important in metabolic growth control under day/night cycle conditions. SasA contains an N-terminal sensory domain with a TRX fold which is involved in the SasA-KaiC interaction. This domain shows high sequence similarity with KaiB. However, the KaiB structure does not show a classical TRX fold. The N-terminal half of KaiB shares the same beta-alpha-beta topology as TRX, but the topology of its C-terminal half diverges.	2.08703e-30
NZ_CP046703.1|WP_114083389.1|5406774_5408058_-|serine-hydroxymethyltransferase	gnl|CDD|234571	PRK00011, glyA, serine hydroxymethyltransferase; Reviewed.	0
NZ_CP046703.1|WP_114083385.1|5403331_5404204_-|DUF2993-domain-containing-protein	gnl|CDD|378597	pfam11209, DUF2993, Protein of unknown function (DUF2993). This family of proteins with unknown function appears to be restricted to Cyanobacteria.	2.1781e-20
NZ_CP046703.1|WP_114083391.1|5409223_5409847_+|DUF4231-domain-containing-protein	gnl|CDD|379418	pfam14015, DUF4231, Protein of unknown function (DUF4231). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea, eukaryotes and viruses. Proteins in this family are typically between 148 and 288 amino acids in length.	1.22052e-36
NZ_CP046703.1|WP_114083394.1|5419161_5420292_+|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)	gnl|CDD|272978	TIGR00236, UDP-N-acetylglucosamine_2-epimerase, UDP-N-acetylglucosamine 2-epimerase. This cytosolic enzyme converts UDP-N-acetyl-D-glucosamine to UDP-N-acetyl-D-mannosamine. In E. coli, this is the first step in the pathway of enterobacterial common antigen biosynthesis.Members of this orthology group have many gene symbols, often reflecting the overall activity of the pathway and/or operon that includes it. Symbols include epsC (exopolysaccharide C) in Burkholderia solanacerum, cap8P (type 8 capsule P) in Staphylococcus aureus, and nfrC in an older designation based on the effects of deletion on phage N4 adsorption. Epimerase activity was also demonstrated in a bifunctional rat enzyme, for which the N-terminal domain appears to be orthologous. The set of proteins found above the suggested cutoff includes E. coli WecB in one of two deeply branched clusters and the rat UDP-N-acetylglucosamine 2-epimerase domain in the other. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	0
NZ_CP046703.1|WP_114083399.1|5423859_5424585_-|Crp/Fnr-family-transcriptional-regulator	gnl|CDD|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	5.53342e-23
NZ_CP046703.1|WP_114083398.1|5422911_5423658_-|Crp/Fnr-family-transcriptional-regulator	gnl|CDD|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	5.84874e-27
NZ_CP046703.1|WP_114083393.1|5416521_5417805_-|type-IV-pilus-twitching-motility-protein-PilT	gnl|CDD|225364	COG2805, PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion].	0
NZ_CP046703.1|WP_114083383.1|5400504_5401455_+|SDR-family-oxidoreductase	gnl|CDD|187541	cd05230, UGD_SDR_e, UDP-glucuronate decarboxylase (UGD) and related proteins, extended (e) SDRs. UGD catalyzes the formation of UDP-xylose from UDP-glucuronate; it is an extended-SDR, and has the characteristic glycine-rich NAD-binding pattern, TGXXGXXG, and active site tetrad. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	0

Protein sequences

>NZ_CP046703.1|WP_114083414.1|5410547_5413328_-|insulinase-family-protein
MKLRSYMFLGFFLSLLLSLLPFSSNFINAATPTVVAPVSADSFTQGVKKTVLDNGLTVLTKEVHTAPVVSVQVWYKVGSRNEVKGENGISHQLEHLMFKGTTARPVQFGRLFSALGSQFNAFTSYDETAYFGTVQRDRLEALLTLEADRMENSLIGPEQLKSEKRVVISELQGYENSPGYRLSRAVMRDAFPNRAYGLSVGGTKADVEKFTVEQVRNYYQTYYSPDNATLVITGDFATEPVLKVVKETYGKLTKRGNEEKRTRENVAPSSPVAPTTKKAPIVLKQPGSAALLQAVYPLPDIKHPDVPAIDVMDAILTGGRSSRLYQALVESGLASSVSGGAAELIEPGWYEINATAAPGQELSKIAQVLQESLGKLQQQPVTTEELNRAKTQLQASYILGNQDITSQASQLGYNQTIAGDYHFIEQYLAAIAKVTPAQVQKVAKTYLNPAKQTIGFFEPTQPDGKPGTSSAGSGRTVENFSPGKPVDPAELAKYLPPATSATDSAKQSLPEEFTLNNGLRVLLLRDRSLPTINLSGQIDAGTEFDGNQKAGLANLTAANLMNGTQTKNALTLAKTLEDLGADLSFSASREGVNVSGEGLSKNLPILIQTLADVLENATFPADQLELSRQRALTSLKVQLDDPRGLGRQVFQQAIYPENHPFHSFPTFESLKSISRDDLLGFYQKYYRPDSTTIAIVGDFDPVKVKTLLNQAFGTWQATGKPPVLKISSVPLPQTSTRLNKIIPGKAEAVTYIGYNGISRKDPRYYAALILNQILGGDTLSSRLGTEVRDRLGLTYGIYSGFAAGINPGPFLIQMQTAPGDTQKAIASTLALLKQLREQGVTEAEFNTAKRSLTNSYPVDLANPSNVSSIILDNAVLGLSRSEIRDFPQRIQAVTMAQMQQAIEDLIKPENLVIVTAGPGEIVPKGG
>NZ_CP046703.1|WP_114083391.1|5409223_5409847_+|DUF4231-domain-containing-protein
MAKKDSYQEFLKEDFNKLFEGMNLGDGQRHFLRSRWLDQVLWMEGKANLSRDRHYLLRITTIIGGVILPALVSLNINTTSTLQVNERSRNIIIWSTFGLSQIVAISAAIEEFFHYGERWRHYRRTVESLKTQGWQFSQLTGPYRDYTSHQQAFNLFAGNVEDVIQRDVEIYSTQVIQEKKEEKQSQENYILMPNAKITNLEEKKEEK
>NZ_CP046703.1|WP_114083390.1|5408467_5409214_+|hypothetical-protein
MKNPLKLTFDRGQTALAIRVDRQAELPDAIEQIGLGGSRSILVVVGGASKISEADFLRIKRLFTEVLAPIAESLGAYVVDGGTDAGVMQLMGEARSQIGAKFALIGVTPENKVALPDQQEPGSDLTPLEPNHTHFVLVPGDNWGDESPWISDVATMLANNAPSVTVLLNGGEITFDDAFYSVNTGRLVVVIAGSGRTADILADALRGEGTDERAKKLAKSGILQYVNLIDIENGVKNLGQIIKDLLSN
>NZ_CP046703.1|WP_114083389.1|5406774_5408058_-|serine-hydroxymethyltransferase
MTRTNSDFLSSTDPAIAELINDELQRQRDHLELIASENFTSAAVLAAQGSVLTNKYAEGLPGKRYYGGCEYVDKIEQLAINRAKQIFGAAHANVQPHSGAQANFAVFLSLLEPGDKIMGMDLSHGGHLTHGSPVNVSGKWFQVSHYGVSQQTEQLDYDQIRELALRERPKLLICGYSAYPRIIDFEKFRSIADEVGAYLLADIAHIAGLVASGLHPDPIPHCHVVTTTTHKTLRGPRGGLILTSDAELGKKLDKSVFPGTQGGPLEHVIAGKAVAFGEALKPEFKTYSAQVIENARALAEQLQNRGLKLVSDGTDNHLLLVDLRSVNLTGKQADKLVSTVNITANKNTIPFDPQSPFVTSGLRLGSPAMTTRGLGVAEFTEIANIISDRLLSPDSDVVTQDCRQRVAALCDRFPLYPHLEIPVPALA
>NZ_CP046703.1|WP_114083388.1|5405403_5406654_-|competence/damage-inducible-protein-A
MSAEIICVGTELLLGDILNGNAQYLAQQLAQLGIPHYYQTVVGDNPERLKQVIEIAISRAQILIFTGGLGPTPDDLTCETIADFFKTPLVENPEIIEDITQKFAQRGRVMSPSNRKQALIPQGAEILPNPTGTAPGIIWQPRPEITIFTFPGVPSEMYPMWEETAVPFLKSQGWGKEIIYSRSLKFWGIGESALAEKVSSYLKLPNPTVAPYAGKGEVRLRVSAKATSEAAAEELIAPIEKQLKEIAGLDFYGVNNDTLASVVGELLRASKETLSVAESCTGGGLGQMLTEISGSSDYFWGGVISYDNSVKVKLLGVNQEDLDKFGAVSATVAEQMAIGVKTRLATTWGLSITGIAGPTGGTDTKPVGLVYVGLAGPKDEVTSFEYQFGTVRGRALIRHVSANAALDNLRRKLLTR
>NZ_CP046703.1|WP_114083387.1|5405094_5405355_-|CopG-family-transcriptional-regulator
MRINARLDDEYADKLAFIQQQTNQAVTDVIKSAIELYYQQLQQEQKNPFSMLTQTGFIGCGESHPDLSVNYKSILRDGLKAKYDYR
>NZ_CP046703.1|WP_114083386.1|5404691_5405108_-|PIN-domain-containing-protein
MIIVDTGFWLALANRNDSYHTQAITVLANVNEPLITTWPVVTKTCYLLLTKMGNHAQVSFINNLFLGAFTVFDLQPHHAKRICELMEKYANLPMDLADASLVVLAEHLGHGRIFSIDFRDFNAYRWKNQYPFENLMVC
>NZ_CP046703.1|WP_114083385.1|5403331_5404204_-|DUF2993-domain-containing-protein
MNHGIACCILHDLLQKYKELLETQNHMFGGLTGLQDPKGTDWGERMLNTVASQTIRHLFTQSESVEVFVRCYPSSKLLQGSIDSFKMSGRGLVIRRDFAVEEMSFETDAVAIDFGSVLKGKLSLKQPTQAIAQVILSEAGINQAFNAELVKKRLLNLTVPSLTELSGGEPVSFTDVQVQLLPENRLQVVAKADLNNGELVPLSMILTVGIERRRRVSFKDPKIELDQVPESQREISQTLSVALVEILDNMVDLDRFDLDGVKMRLNRLETEGQKLIFSGYAEIERIPSSS
>NZ_CP046703.1|WP_114083384.1|5401603_5402995_+|UDP-glucose/GDP-mannose-dehydrogenase-family-protein
MRVCVIGTGYVGLVTGACLAHIGHDVICVDNNEEKVKLMKSGQSPIFEPGLSEIMQSAIQTQKIHFTSDLAAGVSHGEILFIAVGTPPLPTGESDTRYVEAVARGIGENLNGGYKVIVNKSTVPIGSGDWVRMLVLDGVAERQKTLIPAGGVPSDQKLPEFVAEFDVVSNPEFLREGSAVHDTFNPDRIVLGGNSQRAVALMQQLYAPIVERKYAEDQSLPPVPILATDLSSAEMIKYAANAFLATKISFINEVANICDRVGADVTQVAKGIGLDSRIGNKFLQAGIGWGGSCFPKDVSALIHTADDYGYEAQLLKSAVSVNERQRLIALEKLQQVLKILKGKTVGLLGLTFKPDTDDLRDAPALILIEQLNRLGAKVKAYDPIISQTGMRHGLSGVLVETDAERLADGCDALVLVTEWQQFSTLDYVKMAKLMAHPVIIDGRNFLDPETLIRAGFQYVGVGR
>NZ_CP046703.1|WP_114083383.1|5400504_5401455_+|SDR-family-oxidoreductase
MRILVTGGAGFIGSHLIDRLMNEGHELICLDNFYTGHKRNILKWLGHPYFELIRHDITEPIRLEVDQIYHLACPASPVHYQYNPVKTVKTNVMGTLNMLGLAKRVKARFFLASTSEVYGDPEVHPQTEEYRGSVNPIGIRSCYDEGKRIAETLAFDYYRQNKVDIRVVRIFNTYGPRMLENDGRVVSNFIVQALRGNPLTVYGDGSQTRSFCYVSDLVEGFIRLMNSEYIGPMNLGNPGEYTILQLAQAVQNMINPDAQIKFEPLPSDDPRRRQPDITKAKTWLNWEPTIPLQEGLKLTIEDFRNRIQGDVNNSTN
>NZ_CP046703.1|WP_114083392.1|5415534_5416302_-|circadian-clock-protein-KaiB
MNNLTTNKLSTPQLFKGIALFTPGGDLIYCIDPSKQGRWHLHLCSALQEILDLPEPPHFLVPCYTATIDHWLDPRTQQVRTFAEAYPAVIRHQALLNAIFGTGDLVWQAAPWQEGLCDRMVLTSYRSSFGQLWEDHDLIVRLDLSEPVPKYHQPVIVQKKEVITQGYVLRLFVAGHSSTTERILQNLHELLERSLGHPYTLKVIDVLSHPEQAELNQVSATPTLVKVWPHPIRRIVGELDHVEKILQMLAAKEKF
>NZ_CP046703.1|WP_114083393.1|5416521_5417805_-|type-IV-pilus-twitching-motility-protein-PilT
MTESQSPSNSSPVTERNLPPMPPMPPPPPTFSTQRQMTQTLDMSMDRGSNTPVAGHRPVSPPPIPTSVLPKTSSAGPTLEKLIREAYDQGYSDLHLGVGEVPRFRTRGEIQSWDYPEVDKEAFMNWLREVMSEAEIQRFEEHLEFDGATQYDFARVRINVFGTLRGPAMVLRLIPLKILTMEQLRLPPVFRDICHHHKGLILVTGPTGSGKSTTMAAMVDYINKEMAKHIITIEDPIEFIHQSRKSLVKQREVGMHTRKFDNALKAALREDPDLILVGEMRDKETVNTALKAAQTGHLVMGTLHTNSAVKTIERILNLYSGDEQDAMRVAISESLVAVIAQGLCRTTDGKRAAFHDVLINTEAIKEWIKDGKYDEIGELMKQASFDGMITMNQSLLNLYQDGRITEETALEMSPTPNEMAQFLRGRV
>NZ_CP046703.1|WP_012409057.1|5418534_5418909_+|hypothetical-protein
MVSAESSNLGKTYSLLMIKSFLIWTFTLAVCLLVVGFPLVVLMATVGCLLSIILQSVMPVSAVLLVAGALIMFNVMAVVFAAGVLTIKGVHPSEVKWLSWLHGEADQMQTTVYAACPLTCEIKM
>NZ_CP046703.1|WP_114083394.1|5419161_5420292_+|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)
MTNQKRVCIILGTRPEAIKLAPVIQVFQKSLAFESQVILTGQHREMVEQVMQLFNIKADYDLEIMQVQQSLNDITCRSLQGLEALFKEKKPDLVVVQGDTTTAFAAALAAFYQKIPIGHVEAGLRTDDIFNPYPEEANRRLISQITQLHFAPTPWAVENLHRSGVLGEIHMTGNTVIDALLNVAASQAVCNVPGLDWDSYRVMLATVHRRENWGEPLQAIAEGFLQILDKFPDTAMLLPLHRNPTVRVPLQELLGNHPRIFLTDPLDYGELVGAIGRSHLLLTDSGGLQEEAPSLGKPVLVLRDTTERPEAVVAGTAKLVGTTSENIFASATELLSDPDAYAAMANAINPFGDGHAAERILQIVQNYLGVSSEIST
>NZ_CP046703.1|WP_114083395.1|5420547_5421219_-|peptidoglycan-binding-protein
MEYLAYSQMFIAQEEASGNTKYNLPKSQLNGKEPLKSSNIVIAEKQASANSKSKFNWKKLLKSSAWLALAGVGVLLLAATQIQISSAAYVKTNGSCLRIRTGPSTNYSYVDCVSDGATLPAIERYENGFARLSTGRYVYARWVADRPNKPPVTSKPGGVGGSVILTRGSRGQLVRDVQTALGNLRVDGIYGQETVNQVRSFQASKGLLVDGTVGPETRAALGI
>NZ_CP046703.1|WP_114083396.1|5421532_5421943_-|response-regulator
MSNQSMSFKGLRLLVVDDDPDTRTLLTFLFELEGAEIITAASAGAAIEIMSFFKPDIFISDIYLPDENGCSLLMKVRNLEANRGRKIPAIALTASAFDEDQNRALLAGYDIYRCKPIDLDDLSSTVASLVTLEEYA
>NZ_CP046703.1|WP_114083397.1|5422099_5422831_-|Crp/Fnr-family-transcriptional-regulator
MSENTLKPQVNRLLAALPTSDYERLVPHLKLVSLPTRQVIYEPGEPITEVYFPQNAVVSIVTIMEDGSTVEVGIVSNEGMVGIPVILGGNTTTTKAFVQVAGAGMQMDADVLRTEFKRGGAIQKLLLRYVRAIYTELTQGCACNRLHTLEERLARWLLTVSDRLESDDFPLTQEFIAQMLGVRRSGVTVAASTLSRAGMIRYQRGQISILNREDLEATSCECYQVIQKEFARLLGNQPRRDRR
>NZ_CP046703.1|WP_114083398.1|5422911_5423658_-|Crp/Fnr-family-transcriptional-regulator
MSLNKNLFQQPPNKLLAALPASDYERLLPHLKLVKLPVQQILYEAAEPITQVYFPDKAVVSIVTTMEDGSTAEVGIVSNEGMVGIPVILGDNTTTTTAFVQISGAAMQINADVLRNEFNRGGVIQKLLLCYVQAVYSELAQGAACNRLHTLEERLARWLLTVSDRLESEDFPLTHEFISQMLGVRRSGVTVAASTLSRAGMISYQRGHISILNREDLEATSCECHQVIQNEFARLLGFLPSNRAKKIF
>NZ_CP046703.1|WP_114083399.1|5423859_5424585_-|Crp/Fnr-family-transcriptional-regulator
MSLDKNTFDQPANNLLAVLPFSDYERLVPHLKLVKLSNRQVLYEPGEPITEVYFPNKAVVSIITTMEDGSTVEVGLVSNEGMVGMPVILGDNITTTTAFVQIPDSAMQMDADILRSEFNRGTALQSVLLRYVQGVYTQIAQGSACNRLHKLEGRLARWLLTVSDRLESDEFPLTQEFISQMLGVRRAGVTEAANILSEAGMITYHRGQINILNREALEKTSCECYQIIEDEYIRLLGNKLK
>NZ_CP046703.1|WP_159402548.1|5424973_5425144_+|hypothetical-protein
MKLENFTGIAVAIAELSQITFTHHIDTSIFVSDRSKKSLVAQVLATLSLCRCDRIL

Crispr_ID: NZ_CP046703_12

• CRISPR_ID: NZ_CP046703_12
• CRISPR_location: 5418944-5419042
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP046703_12

Consensus_repeat	Method
CCCGGTTAAGCCGGGTTTTTTCATGCT	CRISPRCasFinder

spacers of NZ_CP046703_12

>12.1|5418971|45|NZ_CP046703|CRISPRCasFinder
CTCTAATGATGTGATTACAATTGAATTCGATATACAGTTCATCTA

CRISPR arrays and Neighbor proteins around NZ_CP046703_12

CRISPR arrays

The CRISPR arrays of NZ_CP046703_12

>merge|NZ_CP046703|12|5418944-5419042|CRISPRCasFinder
CCCGGTTAAGCCGGGTTTTTTCATGCTCTCTAATGATGTGATTACAATTGAATTCGATATACAGTTCATCTACCCGATTAAGCCGGGTTTTTTCATGCT

>NZ_CP046703|12|11|5418944-5419042|CRISPRCasFinder
CCCGGTTAAGCCGGGTTTTTTCATGCT	CTCTAATGATGTGATTACAATTGAATTCGATATACAGTTCATCTA
CCCGATTAAGCCGGGTTTTTTCATGCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046703.1|WP_114083396.1|5421532_5421943_-|response-regulator	unknown	unknown	gnl|CDD|381118
NZ_CP046703.1|WP_114083414.1|5410547_5413328_-|insulinase-family-protein	unknown	unknown	gnl|CDD|223685
NZ_CP046703.1|WP_114083390.1|5408467_5409214_+|hypothetical-protein	unknown	unknown	gnl|CDD|375603
NZ_CP046703.1|WP_114083388.1|5405403_5406654_-|competence/damage-inducible-protein-A	unknown	unknown	gnl|CDD|234789
NZ_CP046703.1|WP_114083399.1|5423859_5424585_-|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223736
NZ_CP046703.1|WP_114083397.1|5422099_5422831_-|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223736
NZ_CP046703.1|WP_114083402.1|5428137_5428809_+|glutathione-S-transferase-family-protein	unknown	unknown	gnl|CDD|223698
NZ_CP046703.1|WP_114083394.1|5419161_5420292_+|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)	unknown	unknown	gnl|CDD|272978
NZ_CP046703.1|WP_114083386.1|5404691_5405108_-|PIN-domain-containing-protein	unknown	unknown	gnl|CDD|350263
NZ_CP046703.1|WP_114083392.1|5415534_5416302_-|circadian-clock-protein-KaiB	unknown	unknown	gnl|CDD|239276
NZ_CP046703.1|WP_159402548.1|5424973_5425144_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114083389.1|5406774_5408058_-|serine-hydroxymethyltransferase	unknown	unknown	gnl|CDD|234571
NZ_CP046703.1|WP_114083391.1|5409223_5409847_+|DUF4231-domain-containing-protein	unknown	unknown	gnl|CDD|379418
NZ_CP046703.1|WP_114083387.1|5405094_5405355_-|CopG-family-transcriptional-regulator	unknown	unknown	unknown
NZ_CP046703.1|WP_012409057.1|5418534_5418909_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114083398.1|5422911_5423658_-|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223736
NZ_CP046703.1|WP_114083393.1|5416521_5417805_-|type-IV-pilus-twitching-motility-protein-PilT	unknown	unknown	gnl|CDD|225364
NZ_CP046703.1|WP_114083400.1|5425628_5426666_+|NADP(H)-dependent-aldo-keto-reductase	unknown	unknown	gnl|CDD|381320
NZ_CP046703.1|WP_114083401.1|5426769_5427897_+|PQQ-binding-like-beta-propeller-repeat-protein	unknown	unknown	gnl|CDD|368677
NZ_CP046703.1|WP_114083395.1|5420547_5421219_-|peptidoglycan-binding-protein	unknown	unknown	gnl|CDD|213747

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046703.1|WP_114083396.1|5421532_5421943_-|response-regulator	gnl|CDD|381118	cd17580, REC_2_DhkD-like, second phosphoacceptor receiver (REC) domain of Dictyostelium discoideum hybrid signal transduction histidine kinase D and similar domains. Dictyostelium discoideum hybrid signal transduction histidine kinase D (DhkD) is a large protein that contains two histidine kinase (HK) and two REC domains on the intracellular side of a single pass transmembrane domain, and extracellular PAS and PAC domains that likely are involved in ligand binding. This model represents the second REC domain and similar domains. DhkD activates the cAMP phosphodiesterase RegA to ensure proper prestalk and prespore patterning, tip formation, and the vertical elongation of the mound into a finger, in Dictyostelium discoideum. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	3.61818e-36
NZ_CP046703.1|WP_114083414.1|5410547_5413328_-|insulinase-family-protein	gnl|CDD|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	7.83814e-93
NZ_CP046703.1|WP_114083395.1|5420547_5421219_-|peptidoglycan-binding-protein	gnl|CDD|213747	TIGR02869, Spore_cortex-lytic_enzyme, spore cortex-lytic enzyme. Members of this protein family are the spore cortex-lytic enzyme SleB from Bacillus subtilis and other Gram-positive, endospore-forming bacterial species. This protein is stored in an inactive form in the spore and activated during germination. [Cellular processes, Sporulation and germination].	4.00913e-12
NZ_CP046703.1|WP_114083388.1|5405403_5406654_-|competence/damage-inducible-protein-A	gnl|CDD|234789	PRK00549, PRK00549, competence damage-inducible protein A; Provisional.	0
NZ_CP046703.1|WP_114083402.1|5428137_5428809_+|glutathione-S-transferase-family-protein	gnl|CDD|223698	COG0625, Gst, Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones].	3.26352e-35
NZ_CP046703.1|WP_114083397.1|5422099_5422831_-|Crp/Fnr-family-transcriptional-regulator	gnl|CDD|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	1.99769e-25
NZ_CP046703.1|WP_114083386.1|5404691_5405108_-|PIN-domain-containing-protein	gnl|CDD|350263	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins. Mycobacterium tuberculosis VapC26 cleaves 23S rRNA in the Sarcin-Ricin Loop, it is inhibited by the cognate VapB26 antitoxin. This subfamily belongs to the VapC (virulence-associated protein C)-like nuclease family of the PIN domain-like superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	2.46357e-42
NZ_CP046703.1|WP_114083392.1|5415534_5416302_-|circadian-clock-protein-KaiB	gnl|CDD|239276	cd02978, KaiB_like, KaiB-like family; composed of the circadian clock proteins, KaiB and the N-terminal KaiB-like sensory domain of SasA. KaiB is an essential protein in maintaining circadian rhythm. It was originally discovered from the cyanobacterium Synechococcus as part of the circadian clock gene cluster, kaiABC. KaiB attenuates KaiA-enhanced KaiC autokinase activity by interacting with KaiA-KaiC complexes in a circadian fashion. KaiB is membrane-associated as well as cytosolic. The amount of membrane-associated protein peaks in the evening (at circadian time (CT) 12-16) while the cytosolic form peaks later (at CT 20). The rhythmic localization of KaiB may function in regulating the formation of Kai complexes. SasA is a sensory histidine kinase which associates with KaiC. Although it is not an essential oscillator component, it is important in enhancing kaiABC expression and is important in metabolic growth control under day/night cycle conditions. SasA contains an N-terminal sensory domain with a TRX fold which is involved in the SasA-KaiC interaction. This domain shows high sequence similarity with KaiB. However, the KaiB structure does not show a classical TRX fold. The N-terminal half of KaiB shares the same beta-alpha-beta topology as TRX, but the topology of its C-terminal half diverges.	2.08703e-30
NZ_CP046703.1|WP_114083401.1|5426769_5427897_+|PQQ-binding-like-beta-propeller-repeat-protein	gnl|CDD|368677	pfam05935, Arylsulfotrans, Arylsulfotransferase (ASST). This family consists of several bacterial Arylsulfotransferase proteins. Arylsulfotransferase (ASST) transfers a sulfate group from phenolic sulfate esters to a phenolic acceptor substrate.	3.35155e-30
NZ_CP046703.1|WP_114083389.1|5406774_5408058_-|serine-hydroxymethyltransferase	gnl|CDD|234571	PRK00011, glyA, serine hydroxymethyltransferase; Reviewed.	0
NZ_CP046703.1|WP_114083391.1|5409223_5409847_+|DUF4231-domain-containing-protein	gnl|CDD|379418	pfam14015, DUF4231, Protein of unknown function (DUF4231). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea, eukaryotes and viruses. Proteins in this family are typically between 148 and 288 amino acids in length.	1.22052e-36
NZ_CP046703.1|WP_114083394.1|5419161_5420292_+|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)	gnl|CDD|272978	TIGR00236, UDP-N-acetylglucosamine_2-epimerase, UDP-N-acetylglucosamine 2-epimerase. This cytosolic enzyme converts UDP-N-acetyl-D-glucosamine to UDP-N-acetyl-D-mannosamine. In E. coli, this is the first step in the pathway of enterobacterial common antigen biosynthesis.Members of this orthology group have many gene symbols, often reflecting the overall activity of the pathway and/or operon that includes it. Symbols include epsC (exopolysaccharide C) in Burkholderia solanacerum, cap8P (type 8 capsule P) in Staphylococcus aureus, and nfrC in an older designation based on the effects of deletion on phage N4 adsorption. Epimerase activity was also demonstrated in a bifunctional rat enzyme, for which the N-terminal domain appears to be orthologous. The set of proteins found above the suggested cutoff includes E. coli WecB in one of two deeply branched clusters and the rat UDP-N-acetylglucosamine 2-epimerase domain in the other. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	0
NZ_CP046703.1|WP_114083399.1|5423859_5424585_-|Crp/Fnr-family-transcriptional-regulator	gnl|CDD|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	5.53342e-23
NZ_CP046703.1|WP_114083398.1|5422911_5423658_-|Crp/Fnr-family-transcriptional-regulator	gnl|CDD|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	5.84874e-27
NZ_CP046703.1|WP_114083393.1|5416521_5417805_-|type-IV-pilus-twitching-motility-protein-PilT	gnl|CDD|225364	COG2805, PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion].	0
NZ_CP046703.1|WP_114083400.1|5425628_5426666_+|NADP(H)-dependent-aldo-keto-reductase	gnl|CDD|381320	cd19094, AKR_Tas-like, Escherichia coli Tas protein and similar proteins. Escherichia coli Tas protein is the prototype of this family. It is an NADP(H)-dependent aldo-keto reductase that catalyzes the reversible reduction of ketones to the respective alcohols using NADP(H) as a hydride donor.	0
NZ_CP046703.1|WP_114083390.1|5408467_5409214_+|hypothetical-protein	gnl|CDD|375603	pfam18171, LSDAT_prok, SLOG in TRPM, prokaryote. Family in the SLOG superfamily, fused to or operonically associating with SLATT domain in diverse prokaryotes. Predicted to function as ligand sensor in conjunction with the SLATT transmembrane domain.	1.51245e-80

Protein sequences

>NZ_CP046703.1|WP_012409057.1|5418534_5418909_+|hypothetical-protein
MVSAESSNLGKTYSLLMIKSFLIWTFTLAVCLLVVGFPLVVLMATVGCLLSIILQSVMPVSAVLLVAGALIMFNVMAVVFAAGVLTIKGVHPSEVKWLSWLHGEADQMQTTVYAACPLTCEIKM
>NZ_CP046703.1|WP_114083393.1|5416521_5417805_-|type-IV-pilus-twitching-motility-protein-PilT
MTESQSPSNSSPVTERNLPPMPPMPPPPPTFSTQRQMTQTLDMSMDRGSNTPVAGHRPVSPPPIPTSVLPKTSSAGPTLEKLIREAYDQGYSDLHLGVGEVPRFRTRGEIQSWDYPEVDKEAFMNWLREVMSEAEIQRFEEHLEFDGATQYDFARVRINVFGTLRGPAMVLRLIPLKILTMEQLRLPPVFRDICHHHKGLILVTGPTGSGKSTTMAAMVDYINKEMAKHIITIEDPIEFIHQSRKSLVKQREVGMHTRKFDNALKAALREDPDLILVGEMRDKETVNTALKAAQTGHLVMGTLHTNSAVKTIERILNLYSGDEQDAMRVAISESLVAVIAQGLCRTTDGKRAAFHDVLINTEAIKEWIKDGKYDEIGELMKQASFDGMITMNQSLLNLYQDGRITEETALEMSPTPNEMAQFLRGRV
>NZ_CP046703.1|WP_114083392.1|5415534_5416302_-|circadian-clock-protein-KaiB
MNNLTTNKLSTPQLFKGIALFTPGGDLIYCIDPSKQGRWHLHLCSALQEILDLPEPPHFLVPCYTATIDHWLDPRTQQVRTFAEAYPAVIRHQALLNAIFGTGDLVWQAAPWQEGLCDRMVLTSYRSSFGQLWEDHDLIVRLDLSEPVPKYHQPVIVQKKEVITQGYVLRLFVAGHSSTTERILQNLHELLERSLGHPYTLKVIDVLSHPEQAELNQVSATPTLVKVWPHPIRRIVGELDHVEKILQMLAAKEKF
>NZ_CP046703.1|WP_114083414.1|5410547_5413328_-|insulinase-family-protein
MKLRSYMFLGFFLSLLLSLLPFSSNFINAATPTVVAPVSADSFTQGVKKTVLDNGLTVLTKEVHTAPVVSVQVWYKVGSRNEVKGENGISHQLEHLMFKGTTARPVQFGRLFSALGSQFNAFTSYDETAYFGTVQRDRLEALLTLEADRMENSLIGPEQLKSEKRVVISELQGYENSPGYRLSRAVMRDAFPNRAYGLSVGGTKADVEKFTVEQVRNYYQTYYSPDNATLVITGDFATEPVLKVVKETYGKLTKRGNEEKRTRENVAPSSPVAPTTKKAPIVLKQPGSAALLQAVYPLPDIKHPDVPAIDVMDAILTGGRSSRLYQALVESGLASSVSGGAAELIEPGWYEINATAAPGQELSKIAQVLQESLGKLQQQPVTTEELNRAKTQLQASYILGNQDITSQASQLGYNQTIAGDYHFIEQYLAAIAKVTPAQVQKVAKTYLNPAKQTIGFFEPTQPDGKPGTSSAGSGRTVENFSPGKPVDPAELAKYLPPATSATDSAKQSLPEEFTLNNGLRVLLLRDRSLPTINLSGQIDAGTEFDGNQKAGLANLTAANLMNGTQTKNALTLAKTLEDLGADLSFSASREGVNVSGEGLSKNLPILIQTLADVLENATFPADQLELSRQRALTSLKVQLDDPRGLGRQVFQQAIYPENHPFHSFPTFESLKSISRDDLLGFYQKYYRPDSTTIAIVGDFDPVKVKTLLNQAFGTWQATGKPPVLKISSVPLPQTSTRLNKIIPGKAEAVTYIGYNGISRKDPRYYAALILNQILGGDTLSSRLGTEVRDRLGLTYGIYSGFAAGINPGPFLIQMQTAPGDTQKAIASTLALLKQLREQGVTEAEFNTAKRSLTNSYPVDLANPSNVSSIILDNAVLGLSRSEIRDFPQRIQAVTMAQMQQAIEDLIKPENLVIVTAGPGEIVPKGG
>NZ_CP046703.1|WP_114083391.1|5409223_5409847_+|DUF4231-domain-containing-protein
MAKKDSYQEFLKEDFNKLFEGMNLGDGQRHFLRSRWLDQVLWMEGKANLSRDRHYLLRITTIIGGVILPALVSLNINTTSTLQVNERSRNIIIWSTFGLSQIVAISAAIEEFFHYGERWRHYRRTVESLKTQGWQFSQLTGPYRDYTSHQQAFNLFAGNVEDVIQRDVEIYSTQVIQEKKEEKQSQENYILMPNAKITNLEEKKEEK
>NZ_CP046703.1|WP_114083390.1|5408467_5409214_+|hypothetical-protein
MKNPLKLTFDRGQTALAIRVDRQAELPDAIEQIGLGGSRSILVVVGGASKISEADFLRIKRLFTEVLAPIAESLGAYVVDGGTDAGVMQLMGEARSQIGAKFALIGVTPENKVALPDQQEPGSDLTPLEPNHTHFVLVPGDNWGDESPWISDVATMLANNAPSVTVLLNGGEITFDDAFYSVNTGRLVVVIAGSGRTADILADALRGEGTDERAKKLAKSGILQYVNLIDIENGVKNLGQIIKDLLSN
>NZ_CP046703.1|WP_114083389.1|5406774_5408058_-|serine-hydroxymethyltransferase
MTRTNSDFLSSTDPAIAELINDELQRQRDHLELIASENFTSAAVLAAQGSVLTNKYAEGLPGKRYYGGCEYVDKIEQLAINRAKQIFGAAHANVQPHSGAQANFAVFLSLLEPGDKIMGMDLSHGGHLTHGSPVNVSGKWFQVSHYGVSQQTEQLDYDQIRELALRERPKLLICGYSAYPRIIDFEKFRSIADEVGAYLLADIAHIAGLVASGLHPDPIPHCHVVTTTTHKTLRGPRGGLILTSDAELGKKLDKSVFPGTQGGPLEHVIAGKAVAFGEALKPEFKTYSAQVIENARALAEQLQNRGLKLVSDGTDNHLLLVDLRSVNLTGKQADKLVSTVNITANKNTIPFDPQSPFVTSGLRLGSPAMTTRGLGVAEFTEIANIISDRLLSPDSDVVTQDCRQRVAALCDRFPLYPHLEIPVPALA
>NZ_CP046703.1|WP_114083388.1|5405403_5406654_-|competence/damage-inducible-protein-A
MSAEIICVGTELLLGDILNGNAQYLAQQLAQLGIPHYYQTVVGDNPERLKQVIEIAISRAQILIFTGGLGPTPDDLTCETIADFFKTPLVENPEIIEDITQKFAQRGRVMSPSNRKQALIPQGAEILPNPTGTAPGIIWQPRPEITIFTFPGVPSEMYPMWEETAVPFLKSQGWGKEIIYSRSLKFWGIGESALAEKVSSYLKLPNPTVAPYAGKGEVRLRVSAKATSEAAAEELIAPIEKQLKEIAGLDFYGVNNDTLASVVGELLRASKETLSVAESCTGGGLGQMLTEISGSSDYFWGGVISYDNSVKVKLLGVNQEDLDKFGAVSATVAEQMAIGVKTRLATTWGLSITGIAGPTGGTDTKPVGLVYVGLAGPKDEVTSFEYQFGTVRGRALIRHVSANAALDNLRRKLLTR
>NZ_CP046703.1|WP_114083387.1|5405094_5405355_-|CopG-family-transcriptional-regulator
MRINARLDDEYADKLAFIQQQTNQAVTDVIKSAIELYYQQLQQEQKNPFSMLTQTGFIGCGESHPDLSVNYKSILRDGLKAKYDYR
>NZ_CP046703.1|WP_114083386.1|5404691_5405108_-|PIN-domain-containing-protein
MIIVDTGFWLALANRNDSYHTQAITVLANVNEPLITTWPVVTKTCYLLLTKMGNHAQVSFINNLFLGAFTVFDLQPHHAKRICELMEKYANLPMDLADASLVVLAEHLGHGRIFSIDFRDFNAYRWKNQYPFENLMVC
>NZ_CP046703.1|WP_114083394.1|5419161_5420292_+|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)
MTNQKRVCIILGTRPEAIKLAPVIQVFQKSLAFESQVILTGQHREMVEQVMQLFNIKADYDLEIMQVQQSLNDITCRSLQGLEALFKEKKPDLVVVQGDTTTAFAAALAAFYQKIPIGHVEAGLRTDDIFNPYPEEANRRLISQITQLHFAPTPWAVENLHRSGVLGEIHMTGNTVIDALLNVAASQAVCNVPGLDWDSYRVMLATVHRRENWGEPLQAIAEGFLQILDKFPDTAMLLPLHRNPTVRVPLQELLGNHPRIFLTDPLDYGELVGAIGRSHLLLTDSGGLQEEAPSLGKPVLVLRDTTERPEAVVAGTAKLVGTTSENIFASATELLSDPDAYAAMANAINPFGDGHAAERILQIVQNYLGVSSEIST
>NZ_CP046703.1|WP_114083395.1|5420547_5421219_-|peptidoglycan-binding-protein
MEYLAYSQMFIAQEEASGNTKYNLPKSQLNGKEPLKSSNIVIAEKQASANSKSKFNWKKLLKSSAWLALAGVGVLLLAATQIQISSAAYVKTNGSCLRIRTGPSTNYSYVDCVSDGATLPAIERYENGFARLSTGRYVYARWVADRPNKPPVTSKPGGVGGSVILTRGSRGQLVRDVQTALGNLRVDGIYGQETVNQVRSFQASKGLLVDGTVGPETRAALGI
>NZ_CP046703.1|WP_114083396.1|5421532_5421943_-|response-regulator
MSNQSMSFKGLRLLVVDDDPDTRTLLTFLFELEGAEIITAASAGAAIEIMSFFKPDIFISDIYLPDENGCSLLMKVRNLEANRGRKIPAIALTASAFDEDQNRALLAGYDIYRCKPIDLDDLSSTVASLVTLEEYA
>NZ_CP046703.1|WP_114083397.1|5422099_5422831_-|Crp/Fnr-family-transcriptional-regulator
MSENTLKPQVNRLLAALPTSDYERLVPHLKLVSLPTRQVIYEPGEPITEVYFPQNAVVSIVTIMEDGSTVEVGIVSNEGMVGIPVILGGNTTTTKAFVQVAGAGMQMDADVLRTEFKRGGAIQKLLLRYVRAIYTELTQGCACNRLHTLEERLARWLLTVSDRLESDDFPLTQEFIAQMLGVRRSGVTVAASTLSRAGMIRYQRGQISILNREDLEATSCECYQVIQKEFARLLGNQPRRDRR
>NZ_CP046703.1|WP_114083398.1|5422911_5423658_-|Crp/Fnr-family-transcriptional-regulator
MSLNKNLFQQPPNKLLAALPASDYERLLPHLKLVKLPVQQILYEAAEPITQVYFPDKAVVSIVTTMEDGSTAEVGIVSNEGMVGIPVILGDNTTTTTAFVQISGAAMQINADVLRNEFNRGGVIQKLLLCYVQAVYSELAQGAACNRLHTLEERLARWLLTVSDRLESEDFPLTHEFISQMLGVRRSGVTVAASTLSRAGMISYQRGHISILNREDLEATSCECHQVIQNEFARLLGFLPSNRAKKIF
>NZ_CP046703.1|WP_114083399.1|5423859_5424585_-|Crp/Fnr-family-transcriptional-regulator
MSLDKNTFDQPANNLLAVLPFSDYERLVPHLKLVKLSNRQVLYEPGEPITEVYFPNKAVVSIITTMEDGSTVEVGLVSNEGMVGMPVILGDNITTTTAFVQIPDSAMQMDADILRSEFNRGTALQSVLLRYVQGVYTQIAQGSACNRLHKLEGRLARWLLTVSDRLESDEFPLTQEFISQMLGVRRAGVTEAANILSEAGMITYHRGQINILNREALEKTSCECYQIIEDEYIRLLGNKLK
>NZ_CP046703.1|WP_159402548.1|5424973_5425144_+|hypothetical-protein
MKLENFTGIAVAIAELSQITFTHHIDTSIFVSDRSKKSLVAQVLATLSLCRCDRIL
>NZ_CP046703.1|WP_114083400.1|5425628_5426666_+|NADP(H)-dependent-aldo-keto-reductase
MKYNQLGKSDLKVSEICLGTMTYGQQNTIEEAHAQLDYSIAQGVNFIDAAEMYPVPTSAETYGLTETYIGEWLKRQQREQLIIATKIAGPGRGFKWLRNGAKAIDRDNIKQAVDDSLKRLQTDYIDLYQIHWPDRYVPRFGQTVFDPTQVGETVPIAEQLAVFADVIKAGKIRYIGLSNETPWGVAQFSNAAKQLGLPKVVSIQNAYNLLNRVFDGALAEAVYYEEIGLLAYSPLAFGLLTGKYLNGKPEKARFSLFENFGQRYLKPKVSEAVAAYIDIAKRYQISPVHLALAFVRSRWFVPSTIIGATTLEQLKENLESVDVVLSKDILEELDIVHAQSPNPAP
>NZ_CP046703.1|WP_114083401.1|5426769_5427897_+|PQQ-binding-like-beta-propeller-repeat-protein
MTFTATLIDQNTIRRRGTGLRAYNPEKVFKGYTLFTPLTGQGEVYLLNLEGEVVHQWNLPYPPGLYGYLLPNGNLFYNGKTPPEEPLRFALWAAFKSGVVLEADPKGNIIWEYKHPDHHHDGRRLANGNTIILAIEKIPQSLVPKIKGGVAGTEPDGNIYADVLYEVTPGGEIVWTWHAHEHLDPDKFTITPQDHRHEWTHGNTVGELADGNIIVSFRNISTVVIIDRKTGEIIWTLGDDVLAQQHFPNELANGNILIFDNGAHRRNVALNFSRVIEVNRQTKEIVWEYTDNPPQNFFSAYISGAQRLANGNTLITEGAYGRIFEVTVAGEIVWEYINPYFATRNIPGEKSPVTRGEQNTVFRAFRYAPEEVPWL
>NZ_CP046703.1|WP_114083402.1|5428137_5428809_+|glutathione-S-transferase-family-protein
MAQIKVYSAVVCPYAHRTRLVLQEKGIDFDLIEIDLQNKPEGFTKVSPYGKVPALTHGDNRVWESAVINEYLDEVFPNPPLLPSNPAARAQARIWIDFANTRFVPAFSTLLRSSDPQKQEEAKQELYKHLEFVENEGLAKLSGEGPYWFGESISLVDFTYFPWFERWAALKQYRGFGIPEEFTRVRQWKHALKERESVKAIANSKEFYIERYAKFAAPTLAAV

Crispr_ID: NZ_CP046703_13

• CRISPR_ID: NZ_CP046703_13
• CRISPR_location: 5440397-5440492
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP046703_13

Consensus_repeat	Method
TCTTAACTGTCCTTGCTTTTAAAT	CRISPRCasFinder

spacers of NZ_CP046703_13

>13.1|5440421|48|NZ_CP046703|CRISPRCasFinder
GAAATTTAATTTGATATTTTTCTTAACTGTCTTAACTGTCTTAACTGG

CRISPR arrays and Neighbor proteins around NZ_CP046703_13

CRISPR arrays

The CRISPR arrays of NZ_CP046703_13

>merge|NZ_CP046703|13|5440397-5440492|CRISPRCasFinder
TCTTAACTGTCCTTGCTTTTAAATGAAATTTAATTTGATATTTTTCTTAACTGTCTTAACTGTCTTAACTGGTCTTAACTGTCCTTGTTTTAAATA

>NZ_CP046703|13|12|5440397-5440492|CRISPRCasFinder
TCTTAACTGTCCTTGCTTTTAAAT	GAAATTTAATTTGATATTTTTCTTAACTGTCTTAACTGTCTTAACTGG
TCTTAACTGTCCTTGTTTTAAATA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046703.1|WP_114083408.1|5435976_5436258_+|glutaredoxin-family-protein	unknown	unknown	gnl|CDD|368604
NZ_CP046703.1|WP_159402550.1|5452334_5455040_-|ATP-binding-protein	unknown	unknown	gnl|CDD|378200
NZ_CP046703.1|WP_114083410.1|5438244_5439726_+|ATPase	unknown	unknown	gnl|CDD|223715
NZ_CP046703.1|WP_012409034.1|5449894_5450776_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114083407.1|5435714_5435903_-|DUF4089-domain-containing-protein	unknown	unknown	gnl|CDD|372560
NZ_CP046703.1|WP_114083402.1|5428137_5428809_+|glutathione-S-transferase-family-protein	unknown	unknown	gnl|CDD|223698
NZ_CP046703.1|WP_114083403.1|5428880_5429894_-|NAD(P)-dependent-alcohol-dehydrogenase	unknown	unknown	gnl|CDD|176237
NZ_CP046703.1|WP_114083412.1|5441560_5441977_+|cupin-domain-containing-protein	unknown	unknown	gnl|CDD|380340
NZ_CP046703.1|WP_114083406.1|5434998_5435625_-|DUF4328-domain-containing-protein	unknown	unknown	gnl|CDD|379508
NZ_CP046703.1|WP_114083413.1|5442417_5442639_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114081699.1|5444394_5447568_-|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl|CDD|223911
NZ_CP046703.1|WP_114081517.1|5442964_5444293_+|IS4-family-transposase	unknown	unknown	gnl|CDD|280446
NZ_CP046703.1|WP_114081697.1|5450882_5451998_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|224094
NZ_CP046703.1|WP_114081698.1|5447702_5449160_-|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl|CDD|273776
NZ_CP046703.1|WP_114083409.1|5436311_5437814_+|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,-6-diaminopimelate-ligase	unknown	unknown	gnl|CDD|234660
NZ_CP046703.1|WP_114081694.1|5455332_5456433_-|ATP-binding-protein	unknown	unknown	gnl|CDD|376582
NZ_CP046703.1|WP_114083405.1|5433603_5434989_-|AtzE-family-amidohydrolase	unknown	unknown	gnl|CDD|236409
NZ_CP046703.1|WP_159402467.1|5437911_5438055_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114083411.1|5440584_5441178_+|hypothetical-protein	unknown	unknown	gnl|CDD|238008
NZ_CP046703.1|WP_114083404.1|5433004_5433514_+|N-acetyltransferase	unknown	unknown	gnl|CDD|225695

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046703.1|WP_114083408.1|5435976_5436258_+|glutaredoxin-family-protein	gnl|CDD|368604	pfam05768, DUF836, Glutaredoxin-like domain (DUF836). These proteins are related to the pfam00462 family.	7.16501e-22
NZ_CP046703.1|WP_159402550.1|5452334_5455040_-|ATP-binding-protein	gnl|CDD|378200	pfam09534, Trp_oprn_chp, Tryptophan-associated transmembrane protein (Trp_oprn_chp). Members of this family are predicted transmembrane proteins with four membrane-spanning helices. Members are found in the Actinobacteria (Mycobacterium, Corynebacterium, Streptomyces), always associated with genes for tryptophan biosynthesis.	1.53492e-06
NZ_CP046703.1|WP_114081694.1|5455332_5456433_-|ATP-binding-protein	gnl|CDD|376582	pfam01637, ATPase_2, ATPase domain predominantly from Archaea. This family contain a conserved P-loop motif that is involved in binding ATP. There are eukaryote members as well as archaeal members in this family.	3.55289e-07
NZ_CP046703.1|WP_114081697.1|5450882_5451998_+|ABC-transporter-permease	gnl|CDD|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	6.12223e-86
NZ_CP046703.1|WP_114083407.1|5435714_5435903_-|DUF4089-domain-containing-protein	gnl|CDD|372560	pfam13318, DUF4089, Protein of unknown function (DUF4089). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 60 amino acids in length.	1.47216e-20
NZ_CP046703.1|WP_114083402.1|5428137_5428809_+|glutathione-S-transferase-family-protein	gnl|CDD|223698	COG0625, Gst, Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones].	3.26352e-35
NZ_CP046703.1|WP_114083403.1|5428880_5429894_-|NAD(P)-dependent-alcohol-dehydrogenase	gnl|CDD|176237	cd08276, MDR7, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family. This group is a member of the medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, but lacks the zinc-binding sites of the zinc-dependent alcohol dehydrogenases. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P)-binding Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	0
NZ_CP046703.1|WP_114083412.1|5441560_5441977_+|cupin-domain-containing-protein	gnl|CDD|380340	cd02210, cupin_BLR2406-like, Bradyrhizobium japonicum BLR2406 and related proteins, cupin domain. This family includes bacterial and fungal proteins homologous to BLR2406, a Bradyrhizobium japonicum protein of unknown function with a cupin beta barrel domain. Proteins in this subfamily appear to align closest to RmlC carbohydrate epimerase which is involved in dTDP-L-rhamnose production, and belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	8.87208e-23
NZ_CP046703.1|WP_114083406.1|5434998_5435625_-|DUF4328-domain-containing-protein	gnl|CDD|379508	pfam14219, DUF4328, Domain of unknown function (DUF4328). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 218 and 342 amino acids in length.	0.00208972
NZ_CP046703.1|WP_114081699.1|5444394_5447568_-|efflux-RND-transporter-permease-subunit	gnl|CDD|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NZ_CP046703.1|WP_114081517.1|5442964_5444293_+|IS4-family-transposase	gnl|CDD|280446	pfam02281, Dimer_Tnp_Tn5, Transposase Tn5 dimerization domain. Transposons are mobile DNA sequences capable of replication and insertion into the chromosome. Typically transposons code for the transposase enzyme, which catalyzes insertion, found between terminal inverted repeats. Tn5 has a unique method of self- regulation in which a truncated version of the transposase enzyme acts as an inhibitor. The catalytic domain of the Tn5 transposon is found in pfam01609. This domain mediates dimerization in the known structure.	0.000409103
NZ_CP046703.1|WP_114081698.1|5447702_5449160_-|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl|CDD|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	9.96014e-46
NZ_CP046703.1|WP_114083409.1|5436311_5437814_+|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,-6-diaminopimelate-ligase	gnl|CDD|234660	PRK00139, murE, UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase; Provisional.	0
NZ_CP046703.1|WP_114083405.1|5433603_5434989_-|AtzE-family-amidohydrolase	gnl|CDD|236409	PRK09201, PRK09201, AtzE family amidohydrolase.	0
NZ_CP046703.1|WP_114083410.1|5438244_5439726_+|ATPase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	9.3475e-48
NZ_CP046703.1|WP_114083411.1|5440584_5441178_+|hypothetical-protein	gnl|CDD|238008	cd00051, EFh, EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to the activation or inactivation of target proteins. EF-hands tend to occur in pairs or higher copy numbers.	2.54886e-07
NZ_CP046703.1|WP_114083404.1|5433004_5433514_+|N-acetyltransferase	gnl|CDD|225695	COG3153, COG3153, Predicted acetyltransferase [General function prediction only].	8.76406e-57

Protein sequences

>NZ_CP046703.1|WP_114083410.1|5438244_5439726_+|ATPase
MNVSLTKDLSVYQLVMGVQVPPKPLSLSPATLLSLVRAQIDLLIEQQIAATLWVKLPPEKIWQSELARYQSSVGASSIIYTCQIDENEKQGAGEDDEAGEEKTSSSFSSTHHVTVHLTPDSQLRRENFLMVLSPQFCSLILAHRPLKKRKSQTSGKVNTNKNQPLLIITTVEGRVIQQVLNGIQKAISSDHLPGSSAPESLPIVPADFICPTMPEAATMSQLFTKQLLRQDEVNRQIITARTTKLQQINQELHNKEQFQDEYLKNLCQELRIPLTHIKTALSLLNSPNLKPTQRQRYLQMLNTQCDQQNSLITGLLELVQLERNLEGMVLESVRLSEIVPGVVSTYQPLAQEKGIMLAYTVPTELPSIWCVSGGLRQIVINLLHNSIKFTPNGGEVWVRARLQGDYVQLEFRDTGIGIAENEISKIFERFYRVRTGSTEDYAGAGLGLTIVQQLLLRCGGSISVKSKLYEGSTFTVQLATVGDAPRAIAIEHE
>NZ_CP046703.1|WP_159402467.1|5437911_5438055_+|hypothetical-protein
MALRKAEIWSGQGVGGVGGVGGRGRSLTPTLPTLPTLKKQVISGLCD
>NZ_CP046703.1|WP_114083409.1|5436311_5437814_+|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,-6-diaminopimelate-ligase
MKLRELLTAVDSVEQLPSHPTLQDVEVRGLKTNSHACGVGDLFIGMPGTRVDGGEFWQSAIASGAVAAIVSPEAAQKNPPTNEAVVISASNITQACAQIASAFYGYPGQKLKLVGVTGTNGKTTTTHIIEFLLLKANLATALMGTLYTRWAGFEQTAAHTTPFAVELQQQLAEAVNAGSEFGVMEVSSHALAQGRVLGCQFEVAVFSNLTQDHLDYHRDMEDYFAAKALLFSPDYLKGRAIINADDSYGKRLIASLDAERVWSYSVNDNSADLWMSDLTYEPNGVSGTLHTPKGDVAFRSPLVGQYNLENLLAAVGAALHLGLDLQLVASVIPEFPGVPGRMERVQINSDQDISVIVDYAHTPDSLENLLKAARPFIPGKVICVFGCGGDRDRTKRPIMGRIAAELADVAVVTSDNPRTENPERILEDVLAGIAQTVKPMVICDRATAIRTAILQAQPGDGVLLAGKGHEDYQILGTEKIHFDDREHARDALQQRLNSQA
>NZ_CP046703.1|WP_114083408.1|5435976_5436258_+|glutaredoxin-family-protein
MRLILYSKPGCHLCEGLQEKLEKIQNLSFELEIRDITTRDDWFAAYEYEVPVLYLSNHRGAEDAEGSEKLLPRPSPRGSVQQLEQMLRKYLAN
>NZ_CP046703.1|WP_114083407.1|5435714_5435903_-|DUF4089-domain-containing-protein
MRREGFDVGEYVDLMALLLDLQLRDEYRDGVVANFERISAIANIVNSFPLPEEIEVAPVFEP
>NZ_CP046703.1|WP_114083406.1|5434998_5435625_-|DUF4328-domain-containing-protein
MNNFNAVISLKSASIGRLLVRLLWVLLGFGVASTLLSLLQLIAKPLYQLLASLDALISIVTLLFSLTSIIVFMIWLYRLHADLRDIFKEYPITPGGAIARFLIPIYSLWGIANTLSTFADRFKGEGEDLTRLSEQVRSLIGPLYGFMIGSNLLNRLAFTEAVKNPEDKFLPFWFLFSCILDLGLTAILLQLAKTMQTAITQKAKSAIS
>NZ_CP046703.1|WP_114083405.1|5433603_5434989_-|AtzE-family-amidohydrolase
MNFDSADAITISDAVRAAKVSAVEVTKAAIARIATRDHQLNCFTAVTAETALIDAVRIDEEIAQGNNPGLLAGVPFAVKNLFDIAGLTTLAGSKINAENPAATQDATAIAKLKQAGAVLVGALNMDEYAYGFVTENSHYGATHNPHDLQRVAGGSSGGSAAAVAAGLVPMTLGSDTNGSIRVPAALCGVFGFKPTYGRLSRAGVALFSSSFDHIGPFARSVQDIATVFDVLQGEDDRDPICTKRPPELVLPQLNQDISDIRIAIAADYFTKGSEPEALAAVQKVADALNATQYVTIPEAHRARAAAFVITASEGANLHLEKLRYRPQDFDPATRDRFLAGALIPSSWYLQAQRFRSWYRDRVREVFQNVDLIIAPTTPISAPLIGQQTMILDGEEILVRPHLGLFTQPLSFIGLPVLSVPIQRPNALPLGVQLIAAPYNEALILRVAAALQTKGVVAAVIV
>NZ_CP046703.1|WP_114083404.1|5433004_5433514_+|N-acetyltransferase
MINIRCETLADCTVIAEVNTLAFGQKNEAKLVDKIRRSDRYIPELSLVAEVENVVVGHILFSYINLVSEETLQVIGLAPLAVHPQFQQQGIGSALVQAGLEKADAKKEAVVIVLGHPHFYNRFGFQPSIIYEIESPFLVPEDVFMVKTLQSYEKKYKGKVVYPAAFEEV
>NZ_CP046703.1|WP_114083403.1|5428880_5429894_-|NAD(P)-dependent-alcohol-dehydrogenase
MKAYEIQSNGGIDAIALVDRPEPKPTAGQVLIQVKATSLNYRDLLVAEGAYGAGQKYPLIPLSDGAGEVVAVGEGVTRVKIGDRVAGIFFQDWIYGSLTKEKMKSDLGGGIDGMLAEYVVLHQDGLVILPDYLSYIEGATLPCAAVTAWHGLVTKGNIGAGDSVLLLGTGGVSIFALQFAKIHGARVIITSSSDDKLARAKQLGADETINYKTTPDWEKQVYQLTNRTGVDHVIEVGGAGTLPKSLQAVRIGGRISLIGVLSGRGSEIDPMPILFKSLTVQGIYVGSREIFEAMNQAMQQHQIKPIIDRVFPFTEAREAYSYLKSAAHFGKVVIRNS
>NZ_CP046703.1|WP_114083402.1|5428137_5428809_+|glutathione-S-transferase-family-protein
MAQIKVYSAVVCPYAHRTRLVLQEKGIDFDLIEIDLQNKPEGFTKVSPYGKVPALTHGDNRVWESAVINEYLDEVFPNPPLLPSNPAARAQARIWIDFANTRFVPAFSTLLRSSDPQKQEEAKQELYKHLEFVENEGLAKLSGEGPYWFGESISLVDFTYFPWFERWAALKQYRGFGIPEEFTRVRQWKHALKERESVKAIANSKEFYIERYAKFAAPTLAAV
>NZ_CP046703.1|WP_114083411.1|5440584_5441178_+|hypothetical-protein
MPLVETQDLLDRKFDVCFTHADVNGNGVLEQADVLALAARVATYLGEPMGSPKTQKLFQTFEHFWTHVQAKMDVDNDGQVTPEEWRNGLKSFAEDSEAYKSAFHPLAKAIFTICDRDDNGFLEQSEFAKFHQAFGCKAANSQLAFQKLDSNGNGQLTVDELLIAWQEYYTSSDQNAGGNWLYGDVWDNTVVVGSKTR
>NZ_CP046703.1|WP_114083412.1|5441560_5441977_+|cupin-domain-containing-protein
MSSEILDTCISQQVSSVVVVQEPERICDTDHGYVRGWGVTEETVGSKHLSMAHGIIPPGAGATPHYHPFETAIYIITGTCRVLLGVENDTFVDIKAGDFLYIKTGVVHCPVNYGQEVMEYIVARSSPQEICLYPDQKC
>NZ_CP046703.1|WP_114083413.1|5442417_5442639_+|hypothetical-protein
MVNLFVMIPTGKCDRTVFKGMGSREINLLVLQVELPPLIPPFQGQGCFIPFQTGFVKMVSEKIVSEGDEKMNF
>NZ_CP046703.1|WP_114081517.1|5442964_5444293_+|IS4-family-transposase
MGKHQSVSIRQISKNRAEQIGYYRFLENKSVTVGELVRSLSDHCVSHVEGKHILAISDTSEINLQSHVGRLEALGLGVVGNNRDIGFYIHPTLVLDAANGFPLGISTVKLWTRDINHQDKHERNYSQLPIEEKESYKWLRSADETQQCINVGEAKMITHIGDRESDMYEEFVTVANQDNHVLVRARIDRRLVGKTSSFYTYLNQQPSEGTYTVDVPADARTSRTAREALLIVRRAMVKIQRPDKLNGQDYPPSVTLYAVEAVEVNPPPGQAPIHWRLLTTHQVVCLEQALQVIRWYTWRWRIEQLFATLKTAGLNLEATQLESIAAIQRLTVLALSVAVRILQLIQGRDNPNLPATVAFSHEQQHCLSSISPTLEGKTQLQQNPYLPSSLPWATWIIARLGGWSGYKSQKPPGITTLVRGLEQFESTFFGWKLALGKLVCTP
>NZ_CP046703.1|WP_114081699.1|5444394_5447568_-|efflux-RND-transporter-permease-subunit
MSFNISAWSIKKPVPTIVLFLILTVVGWFSFLSLGIDTNPNIDVPTVSIKVTQPGAGPAELESQVTKKIEDAVAGLGNIDFMISTVSDGNSKTTINFVLGTDSDRATNDVRNAIAQIRQDLPQEINDPIVERLDFAGGPVITYAVKSDKRSVEELSNIVDQTISRALLGVRGVAQIQRVGGVDREIRINLSPNRLQSLGITATQVNDQIRDLNINLPGGRAEVGGSEQSIRTLGSAASVDILKTYEILLPQGGSVPLSSLGTIEDKFGDVRQAATLNNQPVVAFQVLRSTGSVLVTVEQGIKAAVKELEKTLPADVKLDLIFTRADVVRQSYQSTIDELIQASVLAVIVILVFLRDWRATLITAVALPLSIIPTFAVQQALGYTLNNMTLLALALAVGNLVDDAVVEIENMERHIAMGKSAWDAAFESADEVGLAVIASSATIIAVFMPVAFMGGIPGQFFQPFGVTVAVSTIFSTLVARMVTPMMGAYLLKEAGEQGSRGAGEQGEQREQGGRGAGGVIRLFNFKFALPSRKQGNRILRTENRRGFQPYRSLLQWALRHRLTTMAIALAFFIASVMLVPLIPKGFVDDGDFGISNVSIELPPGSTLEDVNKVVTQATDLIRQNPVVERVLATEEINSASLAINLKPREERNISQKQFEEQVRPSFEQIPGARISFQSQSPGDSRKGLSIVLRSENPEALNQAADALEKQMRSLAGLVEVSSTASLVKPEILVIPNPQRAADLGVTVQAIARTASLATIGDNEANLAKFNLSDRQIPIRVQIDPKVRADINTITNLQVLSQNGKLIPLVAVADIRFGSGPATINRYDRARQVAVEANLQGISLGEAVETINKLPVMQNLPPGVVQQPSGSAKIMQEIFGRFGGALGLALMCIYAILVLLYNNFLHPLSIMAALPFCLGGALVALMVAQKPLGIYALIGIVLLLGIVTKNSILLVDYTIINMQEGKTQRQALVEAGVSRLRPILMTSLATIAGILPLALGIGAGSEVRQPMGIAIMGGFTTSTLLTLVVVPVIFSYIDNFQTWIMNRLRYGFGKKPSR
>NZ_CP046703.1|WP_114081698.1|5447702_5449160_-|efflux-RND-transporter-periplasmic-adaptor-subunit
MSDESVSEIEVEEPITSEDAGFLSKSEQKPTRAWLKPLFLGAGLGIAIAFGGMSVLSHLPSRQKSAVADKKINPSMTVTIATVEAARVVRTLKTTGTVAARDLIPVLPQTNGLQIKSIPEDVKEGVFVKKGQVLAVLDDSILQSQISQAKADVESKQADVESKQADLASKQADLASNKAIVQQKQADLAQAKAKLEEAAKNYQRYQQLADSGTISKQELDTRSYAVKTAIQVVNLSQENLRSAQANIGSAQANISNAQAIINKAKADVRSSAARVQQLQTQLEQTVVRAPVSGVIAEKLARVGDVTGVPPQTQVGTVIGGTQKLFSIIRDEKLELQAKVPEIQLNQVKIGASVQITSDVDQRVRSQGRVREIQPQVNDQRREATVKIDLPPTTLLKPGMFANAAITANSGMAMVVPQKAVQSQADGSVIVFTLSSGDIVRSQKIDLENPTNGDKVEIKSGLQLGDRIVVDGAGYLKDGDKVRVAN
>NZ_CP046703.1|WP_012409034.1|5449894_5450776_+|hypothetical-protein
MFNATEILIDAFVNEIREGYRRTYGCFKNDYQDIIAWAGNMALENIANSDALYHNVEHTVLVTLVGQEILRGKHIREGGVSSEDWLHCIISLVSHDIGYVKGVCRLDQEAVGLYSTGKNGKMVSVAPGASDASLTPYHVDRAKLFIDERFGGHKLIDAEAIKSNIELTRFPVPAAEDHQDTKCFAGLVRAADLIGQLSDPRYLKKITSLFYEFEETGVNKVLGYKTPADLRNNYAKFYWNGVYPYIQEGLHYLSLTQQGKQILANLYSNVFVVEHEKQQQEQQKYLEKLGVGS
>NZ_CP046703.1|WP_114081697.1|5450882_5451998_+|ABC-transporter-permease
MDWWRRLKKNPLAQFGAILLLIFYIAVIAADFVAPYDPYASQPNGSLLPPTKIHWVSQSGQFIGPHVYPTTQGDTNLETGDRQLIVDFKKPSPVRLFVSGPEYRLLQMSLPLPPKWDEVTIFPGIPLNWHLFGTTTDAKVNILGTDDQSRDQFSRLLHGGRISMFIGIFGIIITYPLGLLIGGISGYLGGVTDSVIMRLAEVLMTFPSIYLLVTLGAVLPPGLSSTQRFLLIVVITSVISWAGLARVIRGQVLSIKEREFVQASRAMGANPLYIILRHVLPQTASYVVISATLAIPSFIGAEAILSLIGLGIQQPDPSWGNMLSLASNASILVLQPWLIWPPAVLIILTVLAFNLLGDGLRDALDPRSLRR
>NZ_CP046703.1|WP_159402550.1|5452334_5455040_-|ATP-binding-protein
MTPVPRLDLAPKLKRRLYLWNPLDYLRLLYWVFFFPQALRWYVNEFGGGYIPEGEMNWQKGWELLRENAIQRQLLFQGLVLTVVTPVAIGLIFQTANVRINWFGVAFGVAGGVAFGVAGGVEFGVARGVAGSVALCVAGSVAGSVAVGVAGGVARGVAVGVAVGVAGGVARGVVRGVAGSVEFDVAGGVARGVSVGVEFGVAGGVAGGVAFGVAGGVAVGVAGGVAFGVAVLRPETWLIGSPLNLRTIQNSNWLLPRITPLPLPNLVWRLENWLQNDWETGLHNINELLAYTLQFIPVIQAVNRVLAKIPSDQLVWTVSRLAANPFDWDIVRFTSASLNETLKSRFIKDFFSFPLFFFFPHSWREGLQARLNTDTRLNTPARAAAAGFWHLHEKESARAIEAFTVVRSLLYGEEMYTLAQTLTTFQKAQKPASIAAIQVPPFPQEPLLHPVTWKILANLRRVVEDVQFVNRSVSRSARSLALNRALGELTKILNQANTLPQAERGLIIDIAETWQESLLQIAGEVGEISITKPVVNPYVVGDPVQGHLFVGREDIIRQLEELWVMGNQLQSVVLYGHRRMGKTSILVNAANCLGSQIQLAYVNLLRLGDSPQGVGEVLMAICDEISQTVKLSPPADADLLNLPYRTFERYLKQVEAQLDGGLIIALDEFEKIEDLIEANKIPIEFMGFLRGLVQMSSKIAFAFAGLHTLEEMTADYFQPFFASVIPIHVSFQERAATRQILANPDNEDFPLDYIPEALDEIYALTHGQPYLVQLLGFQLVRGYNDFVFEQGRSRDPVFTIEDVEAVINDPEFFKRGRYYFDGVWGQAARGAEGQQAIVRVLAPYPEGLSLDALAQSTGMNDADLQEALNTLKRHDVVEETQGSWRIMVELFRRWVLQFCSK
>NZ_CP046703.1|WP_114081694.1|5455332_5456433_-|ATP-binding-protein
MEAEEALESIKHIFEERKGKVVSLSKLEEKVFLLSWQGMDYGDMTCKIYKPTGKPYTEQYFREIGKKLIDKIKKVLNIDDLDKRNFREELENFFDKNYNYPTKKLSYITAPEPDYTSSPELPNNTLSELNQNPFIPLNARVEEKNLFFDREREIRRIFEVLNSGSSVVLIGEEGIGKSSLLWMINQQAKNFLKSERQPVFLDLNLLHNESQFYSELCHEIGIPDSKDYQLTRNLRSCKILLAIDNVGKLTGEGFTRNIRDYLRGLAEGSNAPLKLILAATEPLNNLFRDSQEQGNTSPLAGICQEEHIHLWDEATMRAFITNRLARSSVSFTEEEIIQLIQESGGHPRKLMQLCYRTYSRYVESLQ

Crispr_ID: NZ_CP046703_14

• CRISPR_ID: NZ_CP046703_14
• CRISPR_location: 5454366-5454731
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 6 spacers

Consensus repeat of NZ_CP046703_14

Consensus_repeat	Method
CACGCCTCNCGCCACGCCTCCNGCCACGCC	CRT

spacers of NZ_CP046703_14

>14.1|5454396|18|NZ_CP046703|CRT
TCCTGCCACGCCAAACGC
>14.2|5454444|18|NZ_CP046703|CRT
GAACTCCACGCCTACCGA
>14.3|5454492|30|NZ_CP046703|CRT
GAACTCCACGCTTCCCGCCACGCCTCGCAC
>14.4|5454552|18|NZ_CP046703|CRT
TACCGCCACGCCTACCGC
>14.5|5454600|42|NZ_CP046703|CRT
TACCGCCACGCTTCCCGCCACGCTTCCCGCCACGCATAACGC
>14.6|5454672|30|NZ_CP046703|CRT
GAACTCCACGCCTCCCGCTACGCCGAACGC

CRISPR arrays and Neighbor proteins around NZ_CP046703_14

CRISPR arrays

The CRISPR arrays of NZ_CP046703_14

>merge|NZ_CP046703|14|5454366-5454731|CRT
CACGCCTCCTGCCACGCCTACCGCCACGCCTCCTGCCACGCCAAACGCCACGCCTCCTGCCACGCCTCCTGCCACGCCGAACTCCACGCCTACCGACACGCCTCGCGCCACGCCTCCTGCCACGTCGAACTCCACGCTTCCCGCCACGCCTCGCACCACGCCTCGCGCCACGCCTCCTGCCACGCCTACCGCCACGCCTACCGCCACGCCTCGCGCCACGCCTCCTGCCACGCCTACCGCCACGCTTCCCGCCACGCTTCCCGCCACGCATAACGCCACGCTTCCCGCCACACCTCGCGCCACGCCGAACTCCACGCCTCCCGCTACGCCGAACGCCACGCCTCCCGCTACGCCGAACGCCACGCC

>NZ_CP046703|14|4|5454366-5454731|CRT
CACGCCTCCTGCCACGCCTACCGCCACGCC	TCCTGCCACGCCAAACGC
CACGCCTCCTGCCACGCCTCCTGCCACGCC	GAACTCCACGCCTACCGA
CACGCCTCGCGCCACGCCTCCTGCCACGTC	GAACTCCACGCTTCCCGCCACGCCTCGCAC
CACGCCTCGCGCCACGCCTCCTGCCACGCC	TACCGCCACGCCTACCGC
CACGCCTCGCGCCACGCCTCCTGCCACGCC	TACCGCCACGCTTCCCGCCACGCTTCCCGCCACGCATAACGC
CACGCTTCCCGCCACACCTCGCGCCACGCC	GAACTCCACGCCTCCCGCTACGCCGAACGC
CACGCCTCCCGCTACGCCGAACGCCACGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046703.1|WP_114081691.1|5458217_5459870_-|peptide-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|173884
NZ_CP046703.1|WP_114083412.1|5441560_5441977_+|cupin-domain-containing-protein	unknown	unknown	gnl|CDD|380340
NZ_CP046703.1|WP_012409034.1|5449894_5450776_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114081686.1|5465381_5466116_+|HAD-family-hydrolase	unknown	unknown	gnl|CDD|223620
NZ_CP046703.1|WP_114081688.1|5462054_5463584_+|photosystem-II-chlorophyll-binding-protein-CP47	unknown	unknown	gnl|CDD|214350
NZ_CP046703.1|WP_114081698.1|5447702_5449160_-|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl|CDD|273776
NZ_CP046703.1|WP_114081694.1|5455332_5456433_-|ATP-binding-protein	unknown	unknown	gnl|CDD|376582
NZ_CP046703.1|WP_114083413.1|5442417_5442639_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114081693.1|5456631_5456973_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114081699.1|5444394_5447568_-|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl|CDD|223911
NZ_CP046703.1|WP_012409025.1|5463695_5463803_+|photosystem-II-reaction-center-protein-T	unknown	unknown	gnl|CDD|183353
NZ_CP046703.1|WP_114081517.1|5442964_5444293_+|IS4-family-transposase	unknown	unknown	gnl|CDD|280446
NZ_CP046703.1|WP_114081690.1|5460083_5460950_-|DNA-adenine-methylase	unknown	unknown	gnl|CDD|223415
NZ_CP046703.1|WP_114081687.1|5464100_5465228_+|30S-ribosomal-protein-S1	unknown	unknown	gnl|CDD|180960
NZ_CP046703.1|WP_114081692.1|5457122_5458148_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|223674
NZ_CP046703.1|WP_114081697.1|5450882_5451998_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|224094
NZ_CP046703.1|WP_114083410.1|5438244_5439726_+|ATPase	unknown	unknown	gnl|CDD|223715
NZ_CP046703.1|WP_114083411.1|5440584_5441178_+|hypothetical-protein	unknown	unknown	gnl|CDD|238008
NZ_CP046703.1|WP_114081689.1|5461249_5461576_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_159402467.1|5437911_5438055_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046703.1|WP_114081691.1|5458217_5459870_-|peptide-ABC-transporter-substrate-binding-protein	gnl|CDD|173884	cd08519, PBP2_NikA_DppA_OppA_like_20, The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold. This CD represents the substrate-binding domain of an uncharacterized ATP-binding cassette (ABC) type nickel/dipeptide/oligopeptide-like transporter. The oligopeptide-binding protein OppA and the dipeptide-binding protein DppA show significant sequence similarity to NikA, the initial nickel receptor. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0
NZ_CP046703.1|WP_114083412.1|5441560_5441977_+|cupin-domain-containing-protein	gnl|CDD|380340	cd02210, cupin_BLR2406-like, Bradyrhizobium japonicum BLR2406 and related proteins, cupin domain. This family includes bacterial and fungal proteins homologous to BLR2406, a Bradyrhizobium japonicum protein of unknown function with a cupin beta barrel domain. Proteins in this subfamily appear to align closest to RmlC carbohydrate epimerase which is involved in dTDP-L-rhamnose production, and belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	8.87208e-23
NZ_CP046703.1|WP_114081697.1|5450882_5451998_+|ABC-transporter-permease	gnl|CDD|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	6.12223e-86
NZ_CP046703.1|WP_114081686.1|5465381_5466116_+|HAD-family-hydrolase	gnl|CDD|223620	COG0546, Gph, Predicted phosphatases [General function prediction only].	6.50619e-32
NZ_CP046703.1|WP_114081698.1|5447702_5449160_-|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl|CDD|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	9.96014e-46
NZ_CP046703.1|WP_114081694.1|5455332_5456433_-|ATP-binding-protein	gnl|CDD|376582	pfam01637, ATPase_2, ATPase domain predominantly from Archaea. This family contain a conserved P-loop motif that is involved in binding ATP. There are eukaryote members as well as archaeal members in this family.	3.55289e-07
NZ_CP046703.1|WP_114081690.1|5460083_5460950_-|DNA-adenine-methylase	gnl|CDD|223415	COG0338, Dam, Site-specific DNA methylase [DNA replication, recombination, and repair].	1.39391e-39
NZ_CP046703.1|WP_114081699.1|5444394_5447568_-|efflux-RND-transporter-permease-subunit	gnl|CDD|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NZ_CP046703.1|WP_012409025.1|5463695_5463803_+|photosystem-II-reaction-center-protein-T	gnl|CDD|183353	PRK11875, psbT, photosystem II reaction center protein T; Reviewed.	1.33296e-11
NZ_CP046703.1|WP_114081517.1|5442964_5444293_+|IS4-family-transposase	gnl|CDD|280446	pfam02281, Dimer_Tnp_Tn5, Transposase Tn5 dimerization domain. Transposons are mobile DNA sequences capable of replication and insertion into the chromosome. Typically transposons code for the transposase enzyme, which catalyzes insertion, found between terminal inverted repeats. Tn5 has a unique method of self- regulation in which a truncated version of the transposase enzyme acts as an inhibitor. The catalytic domain of the Tn5 transposon is found in pfam01609. This domain mediates dimerization in the known structure.	0.000409103
NZ_CP046703.1|WP_114081688.1|5462054_5463584_+|photosystem-II-chlorophyll-binding-protein-CP47	gnl|CDD|214350	CHL00062, psbB, photosystem II 47 kDa protein.	0
NZ_CP046703.1|WP_114081687.1|5464100_5465228_+|30S-ribosomal-protein-S1	gnl|CDD|180960	PRK07400, PRK07400, 30S ribosomal protein S1; Reviewed.	0
NZ_CP046703.1|WP_114081692.1|5457122_5458148_-|ABC-transporter-permease	gnl|CDD|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	2.93126e-114
NZ_CP046703.1|WP_114083410.1|5438244_5439726_+|ATPase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	9.3475e-48
NZ_CP046703.1|WP_114083411.1|5440584_5441178_+|hypothetical-protein	gnl|CDD|238008	cd00051, EFh, EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to the activation or inactivation of target proteins. EF-hands tend to occur in pairs or higher copy numbers.	2.54886e-07

Protein sequences

>NZ_CP046703.1|WP_114081697.1|5450882_5451998_+|ABC-transporter-permease
MDWWRRLKKNPLAQFGAILLLIFYIAVIAADFVAPYDPYASQPNGSLLPPTKIHWVSQSGQFIGPHVYPTTQGDTNLETGDRQLIVDFKKPSPVRLFVSGPEYRLLQMSLPLPPKWDEVTIFPGIPLNWHLFGTTTDAKVNILGTDDQSRDQFSRLLHGGRISMFIGIFGIIITYPLGLLIGGISGYLGGVTDSVIMRLAEVLMTFPSIYLLVTLGAVLPPGLSSTQRFLLIVVITSVISWAGLARVIRGQVLSIKEREFVQASRAMGANPLYIILRHVLPQTASYVVISATLAIPSFIGAEAILSLIGLGIQQPDPSWGNMLSLASNASILVLQPWLIWPPAVLIILTVLAFNLLGDGLRDALDPRSLRR
>NZ_CP046703.1|WP_012409034.1|5449894_5450776_+|hypothetical-protein
MFNATEILIDAFVNEIREGYRRTYGCFKNDYQDIIAWAGNMALENIANSDALYHNVEHTVLVTLVGQEILRGKHIREGGVSSEDWLHCIISLVSHDIGYVKGVCRLDQEAVGLYSTGKNGKMVSVAPGASDASLTPYHVDRAKLFIDERFGGHKLIDAEAIKSNIELTRFPVPAAEDHQDTKCFAGLVRAADLIGQLSDPRYLKKITSLFYEFEETGVNKVLGYKTPADLRNNYAKFYWNGVYPYIQEGLHYLSLTQQGKQILANLYSNVFVVEHEKQQQEQQKYLEKLGVGS
>NZ_CP046703.1|WP_114081698.1|5447702_5449160_-|efflux-RND-transporter-periplasmic-adaptor-subunit
MSDESVSEIEVEEPITSEDAGFLSKSEQKPTRAWLKPLFLGAGLGIAIAFGGMSVLSHLPSRQKSAVADKKINPSMTVTIATVEAARVVRTLKTTGTVAARDLIPVLPQTNGLQIKSIPEDVKEGVFVKKGQVLAVLDDSILQSQISQAKADVESKQADVESKQADLASKQADLASNKAIVQQKQADLAQAKAKLEEAAKNYQRYQQLADSGTISKQELDTRSYAVKTAIQVVNLSQENLRSAQANIGSAQANISNAQAIINKAKADVRSSAARVQQLQTQLEQTVVRAPVSGVIAEKLARVGDVTGVPPQTQVGTVIGGTQKLFSIIRDEKLELQAKVPEIQLNQVKIGASVQITSDVDQRVRSQGRVREIQPQVNDQRREATVKIDLPPTTLLKPGMFANAAITANSGMAMVVPQKAVQSQADGSVIVFTLSSGDIVRSQKIDLENPTNGDKVEIKSGLQLGDRIVVDGAGYLKDGDKVRVAN
>NZ_CP046703.1|WP_114081699.1|5444394_5447568_-|efflux-RND-transporter-permease-subunit
MSFNISAWSIKKPVPTIVLFLILTVVGWFSFLSLGIDTNPNIDVPTVSIKVTQPGAGPAELESQVTKKIEDAVAGLGNIDFMISTVSDGNSKTTINFVLGTDSDRATNDVRNAIAQIRQDLPQEINDPIVERLDFAGGPVITYAVKSDKRSVEELSNIVDQTISRALLGVRGVAQIQRVGGVDREIRINLSPNRLQSLGITATQVNDQIRDLNINLPGGRAEVGGSEQSIRTLGSAASVDILKTYEILLPQGGSVPLSSLGTIEDKFGDVRQAATLNNQPVVAFQVLRSTGSVLVTVEQGIKAAVKELEKTLPADVKLDLIFTRADVVRQSYQSTIDELIQASVLAVIVILVFLRDWRATLITAVALPLSIIPTFAVQQALGYTLNNMTLLALALAVGNLVDDAVVEIENMERHIAMGKSAWDAAFESADEVGLAVIASSATIIAVFMPVAFMGGIPGQFFQPFGVTVAVSTIFSTLVARMVTPMMGAYLLKEAGEQGSRGAGEQGEQREQGGRGAGGVIRLFNFKFALPSRKQGNRILRTENRRGFQPYRSLLQWALRHRLTTMAIALAFFIASVMLVPLIPKGFVDDGDFGISNVSIELPPGSTLEDVNKVVTQATDLIRQNPVVERVLATEEINSASLAINLKPREERNISQKQFEEQVRPSFEQIPGARISFQSQSPGDSRKGLSIVLRSENPEALNQAADALEKQMRSLAGLVEVSSTASLVKPEILVIPNPQRAADLGVTVQAIARTASLATIGDNEANLAKFNLSDRQIPIRVQIDPKVRADINTITNLQVLSQNGKLIPLVAVADIRFGSGPATINRYDRARQVAVEANLQGISLGEAVETINKLPVMQNLPPGVVQQPSGSAKIMQEIFGRFGGALGLALMCIYAILVLLYNNFLHPLSIMAALPFCLGGALVALMVAQKPLGIYALIGIVLLLGIVTKNSILLVDYTIINMQEGKTQRQALVEAGVSRLRPILMTSLATIAGILPLALGIGAGSEVRQPMGIAIMGGFTTSTLLTLVVVPVIFSYIDNFQTWIMNRLRYGFGKKPSR
>NZ_CP046703.1|WP_114081517.1|5442964_5444293_+|IS4-family-transposase
MGKHQSVSIRQISKNRAEQIGYYRFLENKSVTVGELVRSLSDHCVSHVEGKHILAISDTSEINLQSHVGRLEALGLGVVGNNRDIGFYIHPTLVLDAANGFPLGISTVKLWTRDINHQDKHERNYSQLPIEEKESYKWLRSADETQQCINVGEAKMITHIGDRESDMYEEFVTVANQDNHVLVRARIDRRLVGKTSSFYTYLNQQPSEGTYTVDVPADARTSRTAREALLIVRRAMVKIQRPDKLNGQDYPPSVTLYAVEAVEVNPPPGQAPIHWRLLTTHQVVCLEQALQVIRWYTWRWRIEQLFATLKTAGLNLEATQLESIAAIQRLTVLALSVAVRILQLIQGRDNPNLPATVAFSHEQQHCLSSISPTLEGKTQLQQNPYLPSSLPWATWIIARLGGWSGYKSQKPPGITTLVRGLEQFESTFFGWKLALGKLVCTP
>NZ_CP046703.1|WP_114083413.1|5442417_5442639_+|hypothetical-protein
MVNLFVMIPTGKCDRTVFKGMGSREINLLVLQVELPPLIPPFQGQGCFIPFQTGFVKMVSEKIVSEGDEKMNF
>NZ_CP046703.1|WP_114083412.1|5441560_5441977_+|cupin-domain-containing-protein
MSSEILDTCISQQVSSVVVVQEPERICDTDHGYVRGWGVTEETVGSKHLSMAHGIIPPGAGATPHYHPFETAIYIITGTCRVLLGVENDTFVDIKAGDFLYIKTGVVHCPVNYGQEVMEYIVARSSPQEICLYPDQKC
>NZ_CP046703.1|WP_114083411.1|5440584_5441178_+|hypothetical-protein
MPLVETQDLLDRKFDVCFTHADVNGNGVLEQADVLALAARVATYLGEPMGSPKTQKLFQTFEHFWTHVQAKMDVDNDGQVTPEEWRNGLKSFAEDSEAYKSAFHPLAKAIFTICDRDDNGFLEQSEFAKFHQAFGCKAANSQLAFQKLDSNGNGQLTVDELLIAWQEYYTSSDQNAGGNWLYGDVWDNTVVVGSKTR
>NZ_CP046703.1|WP_114083410.1|5438244_5439726_+|ATPase
MNVSLTKDLSVYQLVMGVQVPPKPLSLSPATLLSLVRAQIDLLIEQQIAATLWVKLPPEKIWQSELARYQSSVGASSIIYTCQIDENEKQGAGEDDEAGEEKTSSSFSSTHHVTVHLTPDSQLRRENFLMVLSPQFCSLILAHRPLKKRKSQTSGKVNTNKNQPLLIITTVEGRVIQQVLNGIQKAISSDHLPGSSAPESLPIVPADFICPTMPEAATMSQLFTKQLLRQDEVNRQIITARTTKLQQINQELHNKEQFQDEYLKNLCQELRIPLTHIKTALSLLNSPNLKPTQRQRYLQMLNTQCDQQNSLITGLLELVQLERNLEGMVLESVRLSEIVPGVVSTYQPLAQEKGIMLAYTVPTELPSIWCVSGGLRQIVINLLHNSIKFTPNGGEVWVRARLQGDYVQLEFRDTGIGIAENEISKIFERFYRVRTGSTEDYAGAGLGLTIVQQLLLRCGGSISVKSKLYEGSTFTVQLATVGDAPRAIAIEHE
>NZ_CP046703.1|WP_159402467.1|5437911_5438055_+|hypothetical-protein
MALRKAEIWSGQGVGGVGGVGGRGRSLTPTLPTLPTLKKQVISGLCD
>NZ_CP046703.1|WP_114081694.1|5455332_5456433_-|ATP-binding-protein
MEAEEALESIKHIFEERKGKVVSLSKLEEKVFLLSWQGMDYGDMTCKIYKPTGKPYTEQYFREIGKKLIDKIKKVLNIDDLDKRNFREELENFFDKNYNYPTKKLSYITAPEPDYTSSPELPNNTLSELNQNPFIPLNARVEEKNLFFDREREIRRIFEVLNSGSSVVLIGEEGIGKSSLLWMINQQAKNFLKSERQPVFLDLNLLHNESQFYSELCHEIGIPDSKDYQLTRNLRSCKILLAIDNVGKLTGEGFTRNIRDYLRGLAEGSNAPLKLILAATEPLNNLFRDSQEQGNTSPLAGICQEEHIHLWDEATMRAFITNRLARSSVSFTEEEIIQLIQESGGHPRKLMQLCYRTYSRYVESLQ
>NZ_CP046703.1|WP_114081693.1|5456631_5456973_+|hypothetical-protein
MSTYYPVNENLATQQQPIVQSLDVLSQSNNTEQLLDIAENITAALSKSDTVELVQAGGQTAENIFKVLVQYGGKPVAIILATAVLIAATAIPILAVKVSLGQITQIPNISQTK
>NZ_CP046703.1|WP_114081692.1|5457122_5458148_-|ABC-transporter-permease
MSRSKALQYYIVSRLLLAPLQLLTIITIVFLLLRATPGDPADAILGGRAPEAAKEELRKQLGLNFPLWLQYLNYLGSILRFDLGTSLMSRGQNVWDIIGQYFPATVELAVCSMAVALIVGIAVGTLSASRPGTYFDVGGRLFGIITYALPMFWAGMLLQLIFSVQLGWFPNSNRFPPNLPAPTPVTGLYTIDSLLGGNLSQFFTSLHHLALPSLTLGILLSGIFERIVRVNLKQTLQADYVEAARARGIGENKILASHALKNALIPVITVLGLTFASLLGGAILTEVTFSWPGLANRLYQAIADRDYPTVQGVLVFFGAIVVSASILIDILNAYVDPRIRY
>NZ_CP046703.1|WP_114081691.1|5458217_5459870_-|peptide-ABC-transporter-substrate-binding-protein
MTWFSLSVQRWGRITQFLSLFCLCLFLVVSCAPRPQPPTPPSGSVSSPTGDGRITIGTTAKPRTLDPADAYELASLGLVFNMSDRLYTYEPGSTEIKPQLATALPKVSQDALTYTIPLRQGVVFHDGTPFNAQAMAFTINRFIQNKGKPSFLLADVVDSVKSTSDYELTIKLKKPFAAFPSLLAFPGVCAVSPKAYELGAGKFKPNIFVGTGPYKLAQYGTDSIRFDTFDKYWGEKPANKGVNLQIQTSPVNLFNAFRTGAVDVAYLSLQPDQNRSLEEGGKKGDWQAIAAEGSVVSYLVLNRNQKPLDKLEVRQAIASIIDRPLLNERALLGQADPLYSMIPTTFKVSVPLFKDAYGDANFDQAKKLLTTAGFSKENPAKVQIWYPSSSPTRSLAAQTLKSLVDAKMDGILQFEVTPAEGPTFFKDIAKGLYPGALLDWYPDFLDPDNYVQPFLSCDKGSVAKGCEDGGSQTQGSFYYNEAMNKLIDQQRKELNPEARQKIFAEIQKQVTADVPYVPLWQSKDYVFAQKGVNSVQLNPTQILVYQTIKK
>NZ_CP046703.1|WP_114081690.1|5460083_5460950_-|DNA-adenine-methylase
MNKPINSPFRYPGGKFYARHLILNHIPFHSCYVEPFAGGGSIFFVKDKVNINWLNDIDELLINTLLIIRDQPEELIKFLAGESATKERHTYYKNEFIPQNQLEQAGRWFYLNRTSYSGIMKHQNCYWGYGDKYSMRPENWPRNIRRTSEKLQNVKITNLDFEEVIESVPNGSFLFIDPPYFNADQDKLYAHSFSKDDHFRLCQILNRYKEKIKFLLTYDNNDTIRNLYEWALEIHDKEWNYTISRSDDQKNGKSKQDNLKGERYKGKEIFILNYSSLDSTSPNSEQLI
>NZ_CP046703.1|WP_114081689.1|5461249_5461576_+|hypothetical-protein
MKYFFLSEGWAVARVWASDGLWQVTAWRRQPDIQRMNICLVEENELLWLYRVEEAILTIEVKPTIPVTVGTTIGQVVLKRLMSAEQVIERLNTAEAKCQLQNIHLVVQ
>NZ_CP046703.1|WP_114081688.1|5462054_5463584_+|photosystem-II-chlorophyll-binding-protein-CP47
MGLPWYRVHTVVLNDPGRLISVHLMHTALVAGWAGSMALYELAVYDPSDPILNPMWRQGMFVLPFMSRLGVTQSWGGWNVTGGPASDPGFWSFEGVAAAHIVLSGLLFLAAVWHWVYWDLELFRDPRTGEPALDLPKMFGIHLFLSGLLCFGFGAFHVTGLFGPGIWVSDAYGITGAAQGVAPEWGPDGFNPYNPGGIAAHHIAAGVVGIIAGLFHLTVRPPERLYKALRMGNIETVLSSSIAAVFFAAFVVAGTMWYGNAATPIELFGPTRYQWDQGYFRQEIQRRVQTDVAQGATLDQAWSQIPEKLAFYDYVGNSPAKGGLFRTGPMVKGDGIAQSWQGHAVFKDSEGRELTVRRLPNFFETFPVILTDADGIIRADIPFRRAESKYSFEQSGVTVSFYGGDLNGKTFTEPADVKKYARKAQGGEIFEFDRETLNSDGVFRTSPRGWFTFGHAVFALLFFFGHLWHGSRTIYRDVFAGVDADLEEQVEWGLFQKVGDKSTRRKEAL
>NZ_CP046703.1|WP_012409025.1|5463695_5463803_+|photosystem-II-reaction-center-protein-T
MESVAYILIFTLCIGTIFFAIAFREPPRFEKPKDK
>NZ_CP046703.1|WP_114081687.1|5464100_5465228_+|30S-ribosomal-protein-S1
MVNQNLTATEIGFTHEDFAALLDKYDYHFSPGDVVPGTVFSIEPRGALIDIGAKTAAYIPIQEMSINRVDSPEEVLQSNETREFFILTDENEDGQLTLSIRRIEYMRAWERVRQLQAEDATVRSGVFATNRGGALVRIEGLRGFIPGSHISTRKPKEELVGEELPLKFLEVDEERNRLVLSHRRALVERKMNRLEVGEVVIGTVRGIKPYGAFIDIGGVSGLLHISEISHEHIDTPHSVFNVNDEVKVMIIDLDAERGRISLSTKQLEPEPGDMIKNRDLVYDKAEEMAAKYREQLLAKQQGATAAPAAPADVLAEEDIPPATELEDEIPPAAELEEEIPPAAEIEEVTPVVAEVQEEIPAATETEEEIPAAIEE
>NZ_CP046703.1|WP_114081686.1|5465381_5466116_+|HAD-family-hydrolase
MATIKCRKITFDNIQAILFDKNGTLEDSETYLRSLAQKATRLIDAQIPGTGEPLLMAFGINGNLLDPAGLISVASRRETEVAAAAYIAETGKGWFESLKIARQALDEAEKYIEQTPSPLFVGSLDLLKYLRKGGLKLGILSAATTDEVNKFVAHHQLSDYIQLKMGVDEGPSKPDPVLFLQACEALGVEPGATLMVGDAVGDMQMARNAKAAGCIGITWVGKSDNVRGADVVINQLDEIQILED

Crispr_ID: NZ_CP046703_15

• CRISPR_ID: NZ_CP046703_15
• CRISPR_location: 5602292-5602406
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP046703_15

Consensus_repeat	Method
GAAACACCCACGCTTACATACAAAACATCGTGGA	CRISPRCasFinder

spacers of NZ_CP046703_15

>15.1|5602326|47|NZ_CP046703|CRISPRCasFinder
CAAGTAATTCTATTGATAATACAAATCTGCTGGTACAAAACAATACT

CRISPR arrays and Neighbor proteins around NZ_CP046703_15

CRISPR arrays

The CRISPR arrays of NZ_CP046703_15

>merge|NZ_CP046703|15|5602292-5602406|CRISPRCasFinder
GAAACACCCACGCTTACATACAAAACATCGTGGACAAGTAATTCTATTGATAATACAAATCTGCTGGTACAAAACAATACTGAAACACCCACGCTTACTTACAAAACATCGTGGA

>NZ_CP046703|15|13|5602292-5602406|CRISPRCasFinder
GAAACACCCACGCTTACATACAAAACATCGTGGA	CAAGTAATTCTATTGATAATACAAATCTGCTGGTACAAAACAATACT
GAAACACCCACGCTTACTTACAAAACATCGTGGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046703.1|WP_114082266.1|5596190_5596580_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114082270.1|5588269_5590057_-|aspartate--tRNA-ligase	unknown	unknown	gnl|CDD|234775
NZ_CP046703.1|WP_159402555.1|5608693_5609107_+|hypothetical-protein	unknown	unknown	gnl|CDD|206779
NZ_CP046703.1|WP_159402554.1|5590180_5590327_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114082265.1|5596721_5598020_-|sodium:proton-antiporter	unknown	unknown	gnl|CDD|223104
NZ_CP046703.1|WP_114082279.1|5604457_5605354_-|aspartoacylase	unknown	unknown	gnl|CDD|235019
NZ_CP046703.1|WP_114082263.1|5599230_5600370_-|glycosyltransferase-family-4-protein	unknown	unknown	gnl|CDD|340831
NZ_CP046703.1|WP_114082267.1|5594848_5595955_+|NAD(P)H-binding-protein	unknown	unknown	gnl|CDD|224662
NZ_CP046703.1|WP_114082260.1|5605524_5606694_+|AGE-family-epimerase/isomerase	unknown	unknown	gnl|CDD|225493
NZ_CP046703.1|WP_114082259.1|5606951_5607305_-|Spx/MgsR-family-RNA-polymerase-binding-regulatory-protein	unknown	unknown	gnl|CDD|273720
NZ_CP046703.1|WP_114082264.1|5598760_5599030_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114082258.1|5608116_5608542_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114082262.1|5600445_5601615_-|glycosyltransferase-family-4-protein	unknown	unknown	gnl|CDD|340831
NZ_CP046703.1|WP_114082254.1|5614602_5615040_-|DoxX-family-membrane-protein	unknown	unknown	gnl|CDD|226720
NZ_CP046703.1|WP_114082269.1|5590761_5592870_+|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|224276
NZ_CP046703.1|WP_114082268.1|5593215_5594730_+|C-3',4'-desaturase-CrtD	unknown	unknown	gnl|CDD|274272
NZ_CP046703.1|WP_114082255.1|5614013_5614580_-|DUF2808-domain-containing-protein	unknown	unknown	gnl|CDD|371328
NZ_CP046703.1|WP_114082257.1|5609246_5610530_+|phosphoribosylamine--glycine-ligase	unknown	unknown	gnl|CDD|234856
NZ_CP046703.1|WP_041565423.1|5607786_5607969_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_159402556.1|5610824_5612690_-|carbohydrate-binding-protein	unknown	unknown	gnl|CDD|271150

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046703.1|WP_114082270.1|5588269_5590057_-|aspartate--tRNA-ligase	gnl|CDD|234775	PRK00476, aspS, aspartyl-tRNA synthetase; Validated.	0
NZ_CP046703.1|WP_114082259.1|5606951_5607305_-|Spx/MgsR-family-RNA-polymerase-binding-regulatory-protein	gnl|CDD|273720	TIGR01617, Uncharacterized_protein_UU176, transcriptional regulator, Spx/MgsR family. This model represents a portion of the proteins within the larger set covered by pfam03960. That larger family includes a glutaredoxin-dependent arsenate reductase (TIGR00014). Characterized members of this family include Spx and MgsR from Bacillus subtili. Spx is a global regulator for response to thiol-specific oxidative stress. It interacts with RNA polymerase. MgsR (modulator of the general stress response, also called YqgZ) provides a second level of regulation for more than a third of the proteins in the B. subtilis general stress regulon controlled by Sigma-B. [Regulatory functions, DNA interactions].	1.35654e-41
NZ_CP046703.1|WP_159402555.1|5608693_5609107_+|hypothetical-protein	gnl|CDD|206779	cd11386, MCP_signal, Methyl-accepting chemotaxis protein (MCP), signaling domain. Methyl-accepting chemotaxis proteins (MCPs or chemotaxis receptors) are an integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases. MCPs contain a four helix trans membrane region, an N-terminal periplasmic ligand binding domain, and a C-terminal HAMP domain followed by a cytoplasmic signaling domain. This C-terminal signaling domain dimerizes into a four-helix bundle and interacts with CheA through the adaptor protein CheW.	4.77347e-05
NZ_CP046703.1|WP_114082265.1|5596721_5598020_-|sodium:proton-antiporter	gnl|CDD|223104	COG0025, NhaP, NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism].	6.53197e-67
NZ_CP046703.1|WP_114082279.1|5604457_5605354_-|aspartoacylase	gnl|CDD|235019	PRK02259, PRK02259, aspartoacylase; Provisional.	4.71432e-172
NZ_CP046703.1|WP_114082263.1|5599230_5600370_-|glycosyltransferase-family-4-protein	gnl|CDD|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	1.71591e-56
NZ_CP046703.1|WP_114082267.1|5594848_5595955_+|NAD(P)H-binding-protein	gnl|CDD|224662	COG1748, LYS9, Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism].	3.19461e-86
NZ_CP046703.1|WP_114082260.1|5605524_5606694_+|AGE-family-epimerase/isomerase	gnl|CDD|225493	COG2942, COG2942, N-acyl-D-glucosamine 2-epimerase [Carbohydrate transport and metabolism].	1.01328e-148
NZ_CP046703.1|WP_114082262.1|5600445_5601615_-|glycosyltransferase-family-4-protein	gnl|CDD|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	1.21722e-58
NZ_CP046703.1|WP_114082254.1|5614602_5615040_-|DoxX-family-membrane-protein	gnl|CDD|226720	COG4270, COG4270, Predicted membrane protein [Function unknown].	8.16459e-40
NZ_CP046703.1|WP_114082269.1|5590761_5592870_+|pentapeptide-repeat-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	3.46358e-16
NZ_CP046703.1|WP_114082268.1|5593215_5594730_+|C-3',4'-desaturase-CrtD	gnl|CDD|274272	TIGR02733, similar_to_to_phytoene_dehydrogenase, C-3',4' desaturase CrtD. Members of this family are slr1293, a carotenoid biosynthesis protein which was shown to be the C-3',4' desaturase (CrtD) of myxoxanthophyll biosynthesis in Synechocystis sp. strain PCC 6803, and close homologs (presumed to be functionally equivalent) from other cyanobacteria, where myxoxanthophyll biosynthesis is either known or expected. This enzyme can act on neurosporene and so presumably catalyzes the first step that is committed to myxoxanthophyll. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NZ_CP046703.1|WP_114082255.1|5614013_5614580_-|DUF2808-domain-containing-protein	gnl|CDD|371328	pfam10989, DUF2808, Protein of unknown function (DUF2808). This family of proteins with unknown function appears to be restricted to Cyanobacteria.	1.32521e-61
NZ_CP046703.1|WP_114082257.1|5609246_5610530_+|phosphoribosylamine--glycine-ligase	gnl|CDD|234856	PRK00885, PRK00885, phosphoribosylamine--glycine ligase; Provisional.	0
NZ_CP046703.1|WP_159402556.1|5610824_5612690_-|carbohydrate-binding-protein	gnl|CDD|271150	cd04084, CBM6_xylanase-like, Carbohydrate Binding Module 6 (CBM6); many are appended to glycoside hydrolase (GH) family 11 and GH43 xylanase domains. This family includes carbohydrate binding module 6 (CBM6) domains that are appended mainly to glycoside hydrolase (GH) family domains, including GH3, GH11, and GH43 domains. These CBM6s are non-catalytic carbohydrate binding domains that facilitate the strong binding of the GH catalytic modules with their dedicated, insoluble substrates. Examples of proteins having CMB6s belonging to this family are Microbispora bispora GghA, a 1,4-beta-D-glucan glucohydrolase (GH3); Clostridium thermocellum xylanase U (GH11), and Penicillium purpurogenum ABF3, a bifunctional alpha-L-arabinofuranosidase/xylobiohydrolase (GH43). GH3 comprises enzymes with activities including beta-glucosidase (hydrolyzes beta-galactosidase) and beta-xylosidase (hydrolyzes 1,4-beta-D-xylosidase). GH11 family comprises enzymes with xylanase (endo-1,4-beta-xylanase) activity which catalyze the hydrolysis of beta-1,4 bonds of xylan, the major component of hemicelluloses, to generate xylooligosaccharides and xylose. GH43 includes beta-xylosidases and beta-xylanases, using aryl-glycosides as substrates. CBM6 is an unusual CBM as it represents a chimera of two distinct binding sites with different modes of binding: binding site I within the loop regions and binding site II on the concave face of the beta-sandwich fold.	3.31912e-23

Protein sequences

>NZ_CP046703.1|WP_114082262.1|5600445_5601615_-|glycosyltransferase-family-4-protein
MKNKPEDLASSSASILTLGLGWFPKNPGGLERYIYELTHKLAANKDQVELCGVGLPETELNLPIKLTNLASPDSAIWQRLWSIRTNFQKTRTNKPDAINLHFALYSFPLLDILPKGVPVTFNFHGPWASESQQEVVNKNLSLLIKHHLIEKNTYNRCDRFIVLSKAFGKILHDQYQVPWSKINIIPGGVDINWFQPNLSRQEACKQLGWPNNRRIIFTSRRLVHRTGVDKLLQALAIIKPRIPDVWLAIAGRGHIQAALQQQATELGLDDNIKFLGFLPDEQLPIAYQAAELTIMPSQSFEGFGLVIVESLACGTPVLCTPVGGMPEILSEFSPDLITTSTEASAIAEKLEQVLLGNIPTPSREACREYATTHYDWNQIAQQVRNVLLN
>NZ_CP046703.1|WP_114082263.1|5599230_5600370_-|glycosyltransferase-family-4-protein
MRIFFLDQSGKPGGAELCLIDIAKPYSHRALVGLFADGQFKDLLQQNHIPVEVLATQTIQVRKESSLAQGLKSLKQLAPLITKVIKKAREYDLIYANTQKALVVGALASFFSRRPLVYHLHDILSTEHFSQTNLRIAINLANRCASLVIANSQASKTAFIQAGGRSDIVEVVYNGFDPKIYQTDESDINQLQQKLGLQGKFVVGHFSRLAPWKGQHILIDALAKCPPEVTVILVGDALFGEQDYVKQLHQQVADLGLENRVQFLGFRSDIPQLMAACDLVAHTSTSPEPFGRVIVEAMLCGKPVVAAKAGGVMELVEHGLNGFLVTPGEPQELAQVIITCLQETEITATIANNARTTASRRFDVATINQQIAQLLSHTF
>NZ_CP046703.1|WP_114082264.1|5598760_5599030_+|hypothetical-protein
MMKHYILNLNPTAKHEWDRCILRDPLTAKRPDIAKLIAEAVGADTGSYLVSVNIEVQVLQQAAVPQAEQLSLSFPEVSVQSQPQLREAA
>NZ_CP046703.1|WP_114082265.1|5596721_5598020_-|sodium:proton-antiporter
MVDIYIIDLFVIGLLLLMVTLGSGWIARLPLSFAIIYLIVGIFLGPYAFGLIQLRRDEVFNAELLEKITELVVIISVFSCGLRIVRPLRLGVWDITVRLIVFLMPISIFALAVVGKLFLGMSWGEAILLGAILAPTDPVLASEVQLTDINDQDELRFGLTSEGGLNDALAFPFVYFGLHALKDDNWGNWFKQWIAVDLIWAIAVGIIMGIVVAKSIVWIENKIQKRRPADKLMEDFIAISTILITYSLTEMVNGYGFLAVFVAGLVVQRSYKNPEKPLAQLEFIEQVEKLLEVGTILLLGSILLLKPILNYAMQSLLVIILLFLIIRPIGVWISTIGKRPLDSRRRTFHAETRWLFGWFGIRGVGSLYYLAYAFGNGLKGEAAEQIAWITYTTIVASVIIHGISATPLMKWYERNFANRRKTTPPDTIDEFE
>NZ_CP046703.1|WP_114082266.1|5596190_5596580_+|hypothetical-protein
MQKIRLTLKKALRSSFLVVCLMVSISLSGSFLFVQQTSYATTLEELKLIPPQFKPNSEEKINRANEYDPGVGIQEEERQKAYEQAIKDSKNLNTIEKTYERNLKAEQEQNPPETFGEKAKEVIDKVTGK
>NZ_CP046703.1|WP_114082267.1|5594848_5595955_+|NAD(P)H-binding-protein
MADRVLILGGRGRIGSSVAQDLANHTQAQITITGRSAEFGKAVSLSSGGQVQFLVLDLAEVDKLRDAIANSNLVIHCAGPFHYRDTNVLETCIAKGVNYVDVSDHRSYTSKALHFSKKAAAAGVTAIINTGIFPGISNSMVRQGVEEFDKPEKIHLSYLVSGSGGAGITVMRTTFLGLQYPFEAWIDGKWEIIKPYSEREIVEFPSPYQRTGVYWFDMPETFTLPKAFPSVKTVITKFGSVPDFYNHLTWIAAHIFPKWLMQRRYMIEFLSHVSHSMTDFTNNFSGIGVAVRSEVTGQKDGKTAVYCSTVVHENTAVASGCGTGSIAQLLLEGKLHKPGVFAVEEALQTDLFEEVMQSRGIKINHSWL
>NZ_CP046703.1|WP_114082268.1|5593215_5594730_+|C-3',4'-desaturase-CrtD
MSSITLDKSNSHVVIIGAGIGGLTAGALLAHRGYSVLVLDQALVPGGCASTFKRQGFTFDVGATQVAGLEPGGIHHRIFSELEIDLPQATPCDPACAVYLPGESTPINVWRDQEKWQEERQRQFPGSEPFWQLMATLFDASWEFQGRDPVLPPRNLWDLWQLAQAVRPSTLITVPFTLFTVGDALRLCGLGNDQRLRTFLDLQLKLYSQVDADETALLYAATALSVSQLPQGLFHLQGSMQVLSDRLVQSLERDGGKLLMRHTVEEIKVENGKATAVVIRNQKTGEVWTEAADHIVSNVTVQNLVQLLGEQAPSGYKNRVEKLPQASGAFVVYLGVDASAIPPGCPPHLQFLYDVNGPIGENNSLFVSVSHPGDGRAPEGKATIIASSFVDPAQWWQTEDYEGLKEKFTQEAIARLAQYFYLKPETIIHQEAATPRTFAHFTARDRGIVGGIGQRIPTFGPFGFANRTPIQHLWLVGDSTHPGEGTAGVSYSALTVVRQIEAQM
>NZ_CP046703.1|WP_114082269.1|5590761_5592870_+|pentapeptide-repeat-containing-protein
MPPDYSGQNLQGCSFKGQNLTGANFKNQDIRGADFTNAILKDADFTGAKTGLQKRWVIGLLIISWLLSALSGFLSTLVGVLIASIFDTRITQNPITGVVALIVLAVFFIVTIRKGLTAIAFAIAIAAAIVISFAVAIIIFRASPLAFAGVFTFAGAIGIAIAGVIAVAIAGAIAGAIAGFEAIIGAIIGAIIGAIVGAIIGAIVGAGANTGAVAITAAGAVVITQFGAYIGWRSLAGDEKDAWVRSTAIAFATTGGTSFSNADLTDADFTGAILRNTDFRKANLTRTRFYDAKKLDFARVDNSILANRGVLNLLVTGNGRGKSYASANLKGANLIGANLKEANLKNADITEATFQSACLEWANLTLAQAVGTNFTSAQMTGACVEAWNIESTTKLDNVDCRFIYLLEHPKPGTDDRERRPSGGEFQPGEFTKLFEEVLNTVDLIFHNGIDWKAFVNAFQTVQDQNEDTELALQSIENKGDGVVVVKVGVPDGADKEKIHRDFTQNYQLALQAVEEKYKAQLQAKDEQIIIYRQQSADMKEITNLLANKPINIQVDNKVENKNMTNSNDASRKIEIGSVGRDFNASGQALNLGDISGTVTNTINQLSASPEPDKPGIKELLTQLQAAIEADTNLPQEDKAEALEQVKALAEAGKNPHEGAMQKAAKTAIKILKGTISSLPSATKLVEQCSNLLPLISTFLGLG
>NZ_CP046703.1|WP_159402554.1|5590180_5590327_+|hypothetical-protein
MQTPTPRYDLLRVFALFSSAREMYEILQILKRIAKAMCTTDFANAPVL
>NZ_CP046703.1|WP_114082270.1|5588269_5590057_-|aspartate--tRNA-ligase
MRTHYCGELRKEHIGETVTFYGWVDRRRDHGGVIFLDLRDRTGIVQIVSDPQRTPDSYEHANALRNEYVVAITGRVTQRPEESLNTRIPTGEVEIYADKIELLNAVRKQLPFQVSVADTETVREDLRLKYRYLDLRRERMAQNLQLRHQIVKAMRRYLEDLEGFIEVETPILTRSTPEGARDYVLPSRVNPGEWYALPQSPQLFKQLLMVSGLDRYYQIARCFRDEDLRADRQPEFTQLDMEMSFMSQEEIIELNENLVCHIFKTVKGIELQRPFPRLTYAEGMERYGSDKPDTRYGLELVDVSDIVKDSGFKVFRDTVTNGGIVKILPIPNGNDVISNVRIKPGGDLFKEASEAGAKGLAYIRVRDDGEIDTIGAIKDNLTEEQKQEILRRTGAKAGHLLLFGAGDAATVNKTLDRLRQAIAKEFNLIDPEKINLLWITDFPMFEWNADEKRLEALHHPFTAPHPDDLSDLKTARAQAYDLVLNGVEVGGGSLRIYQREIQQQVFEAIGLSPEEAQSKFGFLLEAFEYGTPPHGGIAYGLDRLVMLLAGEESIRDVIAFPKTQQARCLLTDAPSSVDAKQLKELHVASTYKPKS
>NZ_CP046703.1|WP_114082279.1|5604457_5605354_-|aspartoacylase
MSEIKRVAIVGGNHGNELTGVYLVKKFQQYPNLINRTTFETLPLLGNLKAIEEGKRYIDRDLNRCFTNQGLQNPQLSSYEDTRAKAIQQVLQPQNQPFVDVIVDLHSTTANMGLSLIFCDLNPFLLRLAAYLSSINPMVKIFVNQQSKEGGFLRSLCELGFVIEVGAVAQNILNAELFQQTEQLIYAILDYFEGCNQGNIPQTSSQLTLYQYIETIDYPRSDAYGGLQSGEIQAMIHPQLQFRDYEPLNPGDPMFLTFAGKDIFYEGESTVYPIFINEAAYYEKGIAMYLSQKLQEIV
>NZ_CP046703.1|WP_114082260.1|5605524_5606694_+|AGE-family-epimerase/isomerase
MEYNFQALAELYKNALLNDVLPFWEKYSLDWQQGGYFTCLDREGKIYDTDKFIWLQNRQVWTFSMLYNQLEKRENWLKIASNGANFLAQHGRDSDGNWYFALTREGKPLVEPYNIFSDCFAAMAFSKYALAGGEEWAKDVAMQAYNNVLRRKDNPKGKYNKTYPGTRLMKSLAVPMILANLTLEMEWLLPKETLENVLAETVREVMTDFLDPERGLMYENVAPDGSHIDCFEGRLINPGHGIEAMWFIMDIAHRKNDTKTINQAVDVVLNILNFAWDSEYGGLYYFMDADGHPPQQLEWDQKLWWVHLESLVALAMGYRLTGREVCWEWYQKMHDYTWSHFADSEYGEWFGYLNRRGEVLLNLKGGKWKGCFHVPRALYLCWQQFEALK
>NZ_CP046703.1|WP_114082259.1|5606951_5607305_-|Spx/MgsR-family-RNA-polymerase-binding-regulatory-protein
MSIQVYGIPNCGTCKKALIWLQSNSIEYEFINTKETPPNSEMIENWMKSLGSAPMRNTSGQSYRALGDEKKTWTERQWIDAFTNDAMLLKRPIFVKDGTAVLVGFRDEVVIKTKLKL
>NZ_CP046703.1|WP_041565423.1|5607786_5607969_+|hypothetical-protein
MFPFWGNPCYGSEPISHKASLERKLKFLIWIRDDLESKLAGINASIDTIRQQIERSDSAT
>NZ_CP046703.1|WP_114082258.1|5608116_5608542_-|hypothetical-protein
MSLKTRGSAAVDKAQRRLALLKSINENLDLGHGLTIEAYTRFIDNTRATLEAHNTLLSHLEESRKTMNQMDRGLSELSERMLSAVATVYGKNSMEYSKAGGSNRKRSTSKKSISQVPIVVTVPVTQPTQTVTNGKGRLSDV
>NZ_CP046703.1|WP_159402555.1|5608693_5609107_+|hypothetical-protein
MNSIIYVTASAEIANAVAEIVNVVAEIANVVAEIANVVAEIANVVAEIANVVAEIANVVAEIANAVAEIANAIAEIVNVVAEIANAIAEIANVVACYRRVSALAFRRKGIALQKTSKIKRSLECPISSRQWMYNYKS
>NZ_CP046703.1|WP_114082257.1|5609246_5610530_+|phosphoribosylamine--glycine-ligase
MKVLVVGNGGREHALAWKLLQSKQVEQVVCVPGNGGTASMERCQNLPLAVDDFEDISRYALEHGITLVVVGPEVPLSKGITDYLQDKGLMVFGPVRAGAQIEASKAWAKALMQEAGIPTARAAVFTEVGAAKSYVKSQGAPIVVKADGLAAGKGVIVAETVAQAESAVDAIFQGQFGSAGEFVVIEECLIGQEVSVLALTDGLTIRPLLPAQDHKRIGEGDTGENTGGMGAYSPAPIATPELMARIQTEVLERAIATLRAKGIDYRGVLYAGLMIAPDGDLKVLEFNCRFGDPETQVILPLLETPLEELLLACVQQRLSELPPIAWKKGTSATVVAASGGYPGEYEKGKVITGINNAEVTGATVFHAGTKLNQQQEVVTDGGRVLNVTGIGENFEQAIAQAYAGIKYIQFEGIYYRRDIGHKVVSAK
>NZ_CP046703.1|WP_159402556.1|5610824_5612690_-|carbohydrate-binding-protein
MNYKLSRFFLHTAITLLLLLSLSGISHVLNIPVLEPLKVVAATSTLTIPSSASAPWPVFKRVDALNSSFRSGLNTAWGDYWERSENPFDIGYTEQTQELTNTANGNYAIYNNLDLGSGVEALMLRIALPSGTNSVEVRLGSVSGTVVGTCTINSTGSLSNYRTVPCPLNKSLAKGKQNLVIRFPGSNRSMRFNWFAFWAKDTEQKIDEIQKIQSNNVNQGSPVIPISGRPIRTQNQLPDSSQILAKSYGLWSPGKTWECPKWMHDTYFTKAEDSKVYPTWHPPVDFNPETNTYCTYGHEHGDDPLSSEVFNIAGMPAFGYVNEQLATNNPSNPSLHRNEDHFGHKVLVANNWQMFDESNTSLIKSCDVSLKLHMGTHSPDALVNTAHEMFASGKCDGLEPFNFKHFALFGAAGEFKEPETSLCNLSVNPGITPSPTNQPYGDAHRAIPTAGCYQRGTVDQKTADVNTRNSEYWLTGFAEKSFYFKVTNPSRFYDPSTTTKINRTVNSCYDPTHPLSTTLICEETLAAGSKVEWDDPRSPFRGTTQIETHFSGLAFSDSANSVIYTDAYGRNPRISPAPAQGITFKQIVPVKGFKYDVNGQASLFPPRDYSALGQNGVRAPN
>NZ_CP046703.1|WP_114082255.1|5614013_5614580_-|DUF2808-domain-containing-protein
MRVATLFGITLSLAIGIGGVTLPVTEAVQLRDGTVYFVQPPKLVNARTTYKDVNVWGGTYYFTINLPENAGESLQKVTIAQREGTENIPYNLNDTRAFVGTSERKEFRLTLGPVTDERDTRTVTVNFDPPVTPGQTVTIALRPVSNPSFSGVYLLGVTAFPVGEKSHGQFLGFGRFQFYSNRNSWWFP
>NZ_CP046703.1|WP_114082254.1|5614602_5615040_-|DoxX-family-membrane-protein
MNKYKEILRVVLAISIIVVGVTHFVVPGEYVKIVPPQLPYPLGLVYLSGFYEILGGIGLLVPPVSQAAAWGLLALFIAVYPANINMAVNLIKIEHIPNSPWVHVVRLPLQAVLIAWAWWYTKSSDWEKQASIIPKSLIPKELKLK

Crispr_ID: NZ_CP046703_16

• CRISPR_ID: NZ_CP046703_16
• CRISPR_location: 5753671-5754282
• CRISPR_type: TypeI-D
• Repeat_type: I-D,II-B
• Spacer_info: 8 spacers
• Cas_protein_info: cas2,cas1,cas4,cas6,2OG_CAS,csc1gr5,csc2gr7,cas10d,PD-DExK

Consensus repeat of NZ_CP046703_16

Consensus_repeat	Method
ATTGCAATTCATTAAAATCCCTATCAGGG----------ATTGAAAC	PILER-CR
ATTGCAATTCATTAAAATCCCTATCAGGGATTGAAAC	CRISPRCasFinder
ATTGCAATTCATTAAAATCCCTATCAGGGATTGAAAC	CRT

spacers of NZ_CP046703_16

>16.1|5753708|35|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT
TTGCCAGTAGAGCCAGCCGATCTAGAAGTTGATAT
>16.2|5753780|34|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT
CTTATATATATAGATGTGAATTACATTAAGATGC
>16.3|5753851|32|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT
TGGTACATGGAAAAGGGATTGAATGGTTTCCA
>16.4|5753920|37|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT
TTGCAGTTTTAAAGCCTCTGGTTCAGGCGATTCTTAT
>16.5|5753994|34|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT
ATGAAAGATAATTATGCGAGAGTTGTTGCTATTT
>16.6|5754065|35|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT
TTCCAAAAGACATTATTGAAACAGTAATTAAACCT
>16.7|5754137|37|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT
GAATTATCTAAGCATTATTCAATCTGTGGTACACCAA
>16.8|5754211|35|NZ_CP046703|CRISPRCasFinder,CRT
ATTTGTAATCCCTGCCCTGCTGCGATCGCAATTTC

CRISPR arrays and Neighbor proteins around NZ_CP046703_16

CRISPR arrays

The CRISPR arrays of NZ_CP046703_16

>merge|NZ_CP046703|16|5753671-5754282|PILER-CR,CRISPRCasFinder,CRT
ATTGCAATTCATTAAAATCCCTATCAGGGATTGAAACTTGCCAGTAGAGCCAGCCGATCTAGAAGTTGATATATTGCAATTCATTAAAATCCCTATCAGGGATTGAAACCTTATATATATAGATGTGAATTACATTAAGATGCATTGCAATTCATTAAAATCCCTATCAGGGATTGAAACTGGTACATGGAAAAGGGATTGAATGGTTTCCAATTGCAATTCATTAAAATCCCTATCAGGGATTGAAACTTGCAGTTTTAAAGCCTCTGGTTCAGGCGATTCTTATATTGCAATTCATTAAAATCCCTATCAGGGATTGAAACATGAAAGATAATTATGCGAGAGTTGTTGCTATTTATTGCAATTCATTAAAATCCCTATCAGGGATTGAAACTTCCAAAAGACATTATTGAAACAGTAATTAAACCTATTGCAATTCATTAAAATCCCTATCAGGGATTGAAACGAATTATCTAAGCATTATTCAATCTGTGGTACACCAAATTGCAATTCATTAAAATCCCTATCAGGGATTGAAACATTTGTAATCCCTGCCCTGCTGCGATCGCAATTTCATTGCAATTCATTAAAATCCCTATCAGGCAATACAGT

>NZ_CP046703|16|4|5753671-5754210|PILER-CR
ATTGCAATTCATTAAAATCCCTATCAGGGATTGAAAC	TTGCCAGTAGAGCCAGCCGATCTAGAAGTTGATAT
ATTGCAATTCATTAAAATCCCTATCAGGGATTGAAAC	CTTATATATATAGATGTGAATTACATTAAGATGC
ATTGCAATTCATTAAAATCCCTATCAGGGATTGAAAC	TGGTACATGGAAAAGGGATTGAATGGTTTCCA
ATTGCAATTCATTAAAATCCCTATCAGGGATTGAAAC	TTGCAGTTTTAAAGCCTCTGGTTCAGGCGATTCTTAT
ATTGCAATTCATTAAAATCCCTATCAGGGATTGAAAC	ATGAAAGATAATTATGCGAGAGTTGTTGCTATTT
ATTGCAATTCATTAAAATCCCTATCAGGGATTGAAAC	TTCCAAAAGACATTATTGAAACAGTAATTAAACCT
ATTGCAATTCATTAAAATCCCTATCAGGGATTGAAAC	GAATTATCTAAGCATTATTCAATCTGTGGTACACCAA
ATTGCAATTCATTAAAATCCCTATCAGGGATTGAAAC

>NZ_CP046703|16|14|5753671-5754282|CRISPRCasFinder
ATTGCAATTCATTAAAATCCCTATCAGGGATTGAAAC	TTGCCAGTAGAGCCAGCCGATCTAGAAGTTGATAT
ATTGCAATTCATTAAAATCCCTATCAGGGATTGAAAC	CTTATATATATAGATGTGAATTACATTAAGATGC
ATTGCAATTCATTAAAATCCCTATCAGGGATTGAAAC	TGGTACATGGAAAAGGGATTGAATGGTTTCCA
ATTGCAATTCATTAAAATCCCTATCAGGGATTGAAAC	TTGCAGTTTTAAAGCCTCTGGTTCAGGCGATTCTTAT
ATTGCAATTCATTAAAATCCCTATCAGGGATTGAAAC	ATGAAAGATAATTATGCGAGAGTTGTTGCTATTT
ATTGCAATTCATTAAAATCCCTATCAGGGATTGAAAC	TTCCAAAAGACATTATTGAAACAGTAATTAAACCT
ATTGCAATTCATTAAAATCCCTATCAGGGATTGAAAC	GAATTATCTAAGCATTATTCAATCTGTGGTACACCAA
ATTGCAATTCATTAAAATCCCTATCAGGGATTGAAAC	ATTTGTAATCCCTGCCCTGCTGCGATCGCAATTTC
ATTGCAATTCATTAAAATCCCTATCAGGCAATACAGT

>NZ_CP046703|16|5|5753671-5754282|CRT
ATTGCAATTCATTAAAATCCCTATCAGGGATTGAAAC	TTGCCAGTAGAGCCAGCCGATCTAGAAGTTGATAT
ATTGCAATTCATTAAAATCCCTATCAGGGATTGAAAC	CTTATATATATAGATGTGAATTACATTAAGATGC
ATTGCAATTCATTAAAATCCCTATCAGGGATTGAAAC	TGGTACATGGAAAAGGGATTGAATGGTTTCCA
ATTGCAATTCATTAAAATCCCTATCAGGGATTGAAAC	TTGCAGTTTTAAAGCCTCTGGTTCAGGCGATTCTTAT
ATTGCAATTCATTAAAATCCCTATCAGGGATTGAAAC	ATGAAAGATAATTATGCGAGAGTTGTTGCTATTT
ATTGCAATTCATTAAAATCCCTATCAGGGATTGAAAC	TTCCAAAAGACATTATTGAAACAGTAATTAAACCT
ATTGCAATTCATTAAAATCCCTATCAGGGATTGAAAC	GAATTATCTAAGCATTATTCAATCTGTGGTACACCAA
ATTGCAATTCATTAAAATCCCTATCAGGGATTGAAAC	ATTTGTAATCCCTGCCCTGCTGCGATCGCAATTTC
ATTGCAATTCATTAAAATCCCTATCAGGCAATACAGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046703.1|WP_114082623.1|5754530_5761151_-|HAMP-domain-containing-protein	unknown	unknown	gnl|CDD|236848
NZ_CP046703.1|WP_114082618.1|5767161_5768103_+|cell-wall-hydrolase	unknown	unknown	gnl|CDD|119407
NZ_CP046703.1|WP_114082631.1|5747491_5748508_+|type-I-D-CRISPR-associated-protein-Cas7/Csc2	csc2gr7	cd09709_csc2gr7_CAS-I-D	gnl|CDD|375747
NZ_CP046703.1|WP_114082624.1|5753114_5753402_+|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187856
NZ_CP046703.1|WP_114082626.1|5751246_5751840_+|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl|CDD|273040
NZ_CP046703.1|WP_114082632.1|5744152_5747443_+|type-I-D-CRISPR-associated-protein-Cas10d/Csc3	cas10d	cd09712_cas10d_CAS-I-D	gnl|CDD|274469
NZ_CP046703.1|WP_114082627.1|5750345_5751215_+|CRISPR-associated-endoribonuclease-Cas6	cas6	COG5551_cas6_CAS-III	gnl|CDD|227838
NZ_CP046703.1|WP_114082621.1|5761721_5762207_-|PIN-domain-containing-protein	unknown	unknown	gnl|CDD|350222
NZ_CP046703.1|WP_114082630.1|5748507_5749215_+|type-I-D-CRISPR-associated-protein-Cas5/Csc1	csc1gr5	cd09711_csc1gr5_CAS-I-D	gnl|CDD|187842
NZ_CP046703.1|WP_114082629.1|5749215_5749626_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114082619.1|5762546_5766323_-|magnesium-chelatase-subunit-H	unknown	unknown	gnl|CDD|215643
NZ_CP046703.1|WP_114082616.1|5769520_5771860_+|sodium:calcium-exchanger	unknown	unknown	gnl|CDD|223551
NZ_CP046703.1|WP_114082633.1|5743115_5744135_+|DUF1016-domain-containing-protein	PD-DExK	COG4804_PD-DExK_CAS-I:CAS-III	gnl|CDD|377634
NZ_CP046703.1|WP_114082617.1|5768366_5769344_+|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|187664
NZ_CP046703.1|WP_114082615.1|5772247_5772946_+|PEP-CTERM-sorting-domain-containing-protein	unknown	unknown	gnl|CDD|131644
NZ_CP046703.1|WP_114082614.1|5773124_5778677_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|226415
NZ_CP046703.1|WP_114082620.1|5762272_5762494_-|type-II-toxin-antitoxin-system-HicB-family-antitoxin	unknown	unknown	gnl|CDD|224514
NZ_CP046703.1|WP_114082628.1|5749735_5750356_+|2OG-Fe(II)-oxygenase	2OG_CAS	-	gnl|CDD|379309
NZ_CP046703.1|WP_114082625.1|5752051_5753056_+|type-I-D-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl|CDD|274976
NZ_CP046703.1|WP_114082622.1|5761513_5761738_-|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP046703.1|WP_114082633.1|5743115_5744135_+|DUF1016-domain-containing-protein	PD-DExK	COG4804_PD-DExK_CAS-I:CAS-III	8.6e-44	143.9	4.0
NZ_CP046703.1|WP_114082631.1|5747491_5748508_+|type-I-D-CRISPR-associated-protein-Cas7/Csc2	csc2gr7	cd09709_csc2gr7_CAS-I-D	3.2e-109	359.2	0.1
NZ_CP046703.1|WP_114082624.1|5753114_5753402_+|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	1.9e-31	102.9	0.0
NZ_CP046703.1|WP_114082626.1|5751246_5751840_+|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	9.4e-49	160.7	1.4
NZ_CP046703.1|WP_114082632.1|5744152_5747443_+|type-I-D-CRISPR-associated-protein-Cas10d/Csc3	cas10d	cd09712_cas10d_CAS-I-D	0	1137.9	0.3
NZ_CP046703.1|WP_114082627.1|5750345_5751215_+|CRISPR-associated-endoribonuclease-Cas6	cas6	COG5551_cas6_CAS-III	2.9e-76	251.2	0.0
NZ_CP046703.1|WP_114082628.1|5749735_5750356_+|2OG-Fe(II)-oxygenase	2OG_CAS	-	2e-138	453.3	0.3
NZ_CP046703.1|WP_114082625.1|5752051_5753056_+|type-I-D-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	1.2e-108	357.9	0.0
NZ_CP046703.1|WP_114082630.1|5748507_5749215_+|type-I-D-CRISPR-associated-protein-Cas5/Csc1	csc1gr5	cd09711_csc1gr5_CAS-I-D	8.7e-88	288.0	2.3

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046703.1|WP_114082623.1|5754530_5761151_-|HAMP-domain-containing-protein	gnl|CDD|236848	PRK11107, PRK11107, hybrid sensory histidine kinase BarA; Provisional.	1.47241e-73
NZ_CP046703.1|WP_114082615.1|5772247_5772946_+|PEP-CTERM-sorting-domain-containing-protein	gnl|CDD|131644	TIGR02595, conserved_hypothetical_protein, PEP-CTERM protein-sorting domain. This model describes a 25-residue domain that includes a near-invariant Pro-Glu-Pro (PEP) motif, a thirteen residue strongly hydrophobic sequence likely to span the membrane, and a five-residue strongly basic motif that often contains four Arg residues. In nearly every case, this motif is found within nine residues, and usually within five residues, of the extreme C-terminus of the protein. Proteins with this motif typically have signal sequences at the N-terminus. This region appears many times per genome or not at all, and co-occurs in genomes with a proposed protein-sorting integral membrane protein we designate exosortase (see TIGR02602). PEP-CTERM proteins frequently are poorly conserved, Ser/Thr-rich proteins and may become extensively modified proteinaceous constituents of extracellular material in bacterial biofilms. [Cell envelope, Surface structures].	0.00214471
NZ_CP046703.1|WP_114082631.1|5747491_5748508_+|type-I-D-CRISPR-associated-protein-Cas7/Csc2	gnl|CDD|375747	pfam18320, Csc2, Csc2 Crispr. The Csc2 Crispr family of proteins forms a core RNA recognition motif-like domain, flanked by three peripheral insertion domains: a lid domain, a Zinc-binding domain and a helical domain. The CRISPR-Cas system is possibly a mechanism of defence against invading pathogens and plasmids that functions analogously to the RNA interference (RNAi) systems in eukaryotes.	9.59213e-177
NZ_CP046703.1|WP_114082624.1|5753114_5753402_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.33704e-36
NZ_CP046703.1|WP_114082626.1|5751246_5751840_+|CRISPR-associated-protein-Cas4	gnl|CDD|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	2.92518e-55
NZ_CP046703.1|WP_114082632.1|5744152_5747443_+|type-I-D-CRISPR-associated-protein-Cas10d/Csc3	gnl|CDD|274469	TIGR03174, cas_Csc3, CRISPR type I-D/CYANO-associated protein Csc3/Cas10d. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This protein family is a CRISPR-associated (Cas) family strictly associated with the Cyano subtype of CRISPR/Cas locus, found in several species of Cyanobacteria and several archaeal species. This family is designated Csc3 for CRISPR/Cas Subtype Cyano protein 3, as it is often the third gene upstream of the core cas genes, cas3-cas4-cas1-cas2.	0
NZ_CP046703.1|WP_114082627.1|5750345_5751215_+|CRISPR-associated-endoribonuclease-Cas6	gnl|CDD|227838	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	2.84688e-62
NZ_CP046703.1|WP_114082621.1|5761721_5762207_-|PIN-domain-containing-protein	gnl|CDD|350222	cd09874, PIN_MT3492-like, VapC-like PIN domain of the hypothetical protein MT3492 of Mycobacterium tuberculosis CDC1551 and other uncharacterized, annotated PilT protein domain proteins. Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis CDC1551, hypothetical protein MT3492, and similar bacterial and archaeal proteins are included in this subfamily. They are PIN domain homologs of the Mycobacterium tuberculosis VapC and Neisseria gonorrhoeae FitB toxins of the prokaryotic toxin/antitoxin operons, VapBC and FitAB, respectively, which are believed to be involved in growth inhibition by regulating translation. These toxins are nearly always co-expressed with an antitoxin, a cognate protein inhibitor, forming an inert protein complex. Disassociation of the protein complex activates the ribonuclease activity of the toxin by an, as yet undefined mechanism. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	1.50628e-06
NZ_CP046703.1|WP_114082630.1|5748507_5749215_+|type-I-D-CRISPR-associated-protein-Cas5/Csc1	gnl|CDD|187842	cd09711, Csc1_I-D, CRISPR/Cas system-associated protein Csc1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; predicted Cas5 ortholog; also known as CasA/Cse1 family.	3.07798e-93
NZ_CP046703.1|WP_114082619.1|5762546_5766323_-|magnesium-chelatase-subunit-H	gnl|CDD|215643	PLN03241, PLN03241, magnesium chelatase subunit H; Provisional.	0
NZ_CP046703.1|WP_114082618.1|5767161_5768103_+|cell-wall-hydrolase	gnl|CDD|119407	cd02696, MurNAc-LAA, N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino acids in certain cell wall glycopeptides. These proteins are Zn-dependent peptidases with highly conserved residues involved in cation co-ordination. MurNAc-LAA in this family is one of several peptidoglycan hydrolases (PGHs) found in bacterial and bacteriophage or prophage genomes that are involved in the degradation of the peptidoglycan. In Escherichia coli, there are five MurNAc-LAAs present: AmiA, AmiB, AmiC and AmiD that are periplasmic, and AmpD that is cytoplasmic. Three of these (AmiA, AmiB and AmiC) belong to this family, the other two (AmiD and AmpD) do not. E. coli AmiA, AmiB and AmiC play an important role in cleaving the septum to release daughter cells after cell division. In general, bacterial MurNAc-LAAs are members of the bacterial autolytic system and carry a signal peptide in their N-termini that allows their transport across the cytoplasmic membrane. However, the bacteriophage MurNAc-LAAs are endolysins since these phage-encoded enzymes break down bacterial peptidoglycan at the terminal stage of the phage reproduction cycle. As opposed to autolysins, almost all endolysins have no signal peptides and their translocation through the cytoplasmic membrane is thought to proceed with the help of phage-encoded holin proteins. The amidase catalytic module is fused to another functional module (cell wall binding module or CWBM) either at the N- or C-terminus, which is responsible for high affinity binding of the protein to the cell wall.	4.75734e-50
NZ_CP046703.1|WP_114082633.1|5743115_5744135_+|DUF1016-domain-containing-protein	gnl|CDD|377634	pfam06250, DUF1016, Protein of unknown function (DUF1016). Family of uncharacterized proteins found in viruses, archaea and bacteria.	6.55737e-83
NZ_CP046703.1|WP_114082617.1|5768366_5769344_+|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|187664	cd09763, DHRS1-like_SDR_c, human dehydrogenase/reductase (SDR family) member 1 (DHRS1) -like, classical (c) SDRs. This subgroup includes human DHRS1 and related proteins. These are members of the classical SDR family, with a canonical Gly-rich NAD-binding motif and the typical YXXXK active site motif. However, the rest of the catalytic tetrad is not strongly conserved. DHRS1 mRNA has been detected in many tissues, liver, heart, skeletal muscle, kidney and pancreas; a longer transcript is predominantly expressed in the liver , a shorter one in the heart. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRS are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes have a 3-glycine N-terminal NAD(P)(H)-binding pattern (typically, TGxxxGxG in classical SDRs and TGxxGxxG in extended SDRs), while substrate binding is in the C-terminal region. A critical catalytic Tyr residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering), is often found in a conserved YXXXK pattern. In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) or additional Ser, contributing to the active site. Substrates for these enzymes include sugars, steroids, alcohols, and aromatic compounds. The standard reaction mechanism is a proton relay involving the conserved Tyr and Lys, as well as Asn (or Ser). Some SDR family members, including 17 beta-hydroxysteroid dehydrogenase contain an additional helix-turn-helix motif that is not generally found among SDRs.	2.6397e-113
NZ_CP046703.1|WP_114082614.1|5773124_5778677_-|AAA-family-ATPase	gnl|CDD|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	0
NZ_CP046703.1|WP_114082620.1|5762272_5762494_-|type-II-toxin-antitoxin-system-HicB-family-antitoxin	gnl|CDD|224514	COG1598, COG1598, Predicted nuclease of the RNAse H fold, HicB family [General function prediction only].	1.11742e-05
NZ_CP046703.1|WP_114082628.1|5749735_5750356_+|2OG-Fe(II)-oxygenase	gnl|CDD|379309	pfam13640, 2OG-FeII_Oxy_3, 2OG-Fe(II) oxygenase superfamily. This family contains members of the 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily.	3.93228e-09
NZ_CP046703.1|WP_114082625.1|5752051_5753056_+|type-I-D-CRISPR-associated-endonuclease-Cas1	gnl|CDD|274976	TIGR04093, hypothetical_protein_L8106_25395, CRISPR-associated endonuclease Cas1, subtype CYANO. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes a clade of Cas1 limited to the CYANO subtype of CRISPR/Cas system and most often the type found there.	2.57362e-155
NZ_CP046703.1|WP_114082616.1|5769520_5771860_+|sodium:calcium-exchanger	gnl|CDD|223551	COG0475, KefB, Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism].	1.37232e-92

Protein sequences

>NZ_CP046703.1|WP_114082624.1|5753114_5753402_+|CRISPR-associated-endonuclease-Cas2
MYIVVSYDIPEDKRRTKIHSILKSYGQWMQLSVFECDITPTQYAKLRSRLSKLIKPDTDSVRFYFLCGCCQRKVERIGGEQPRDETIFFAESPSG
>NZ_CP046703.1|WP_114082625.1|5752051_5753056_+|type-I-D-CRISPR-associated-endonuclease-Cas1
MGTLYVTQADAFIGKVDERLTVKAEQKTILDIPLIKLEGIVVLGRATISPAVVSELLERHICLTFLTQNGRYLGRLEPEVTKNIFVRKAQWQAVGESEPAIHLVRGFVRGKLKNYRHTLLRTQREHPDTDLNNNITRLENAIAPIEKTSSIDSLRGLEGAGSAAYFGCFQQLIKTPEFRFEARKRRPPTDPVNALLSFGYTLLRHDVQSALNIVGFDPYLGYLHVERYGRPSLALDLMEEFRPLIVDAVVLSLINKRSLTLTDFTTEPLSGAVSLTKEGLHTFLRAYQQKKLSSFKHPVMGNKCTYQESFEIQARLLSKYLMNEIDKYPPLILK
>NZ_CP046703.1|WP_114082626.1|5751246_5751840_+|CRISPR-associated-protein-Cas4
MNQTEYISIAALNQYAYCPHRCWRMFCAGEFTDNQYTIEGTTLHDRVHTTSDVQRGETWQIRAIWLKSEQYKLIGKSDLIEEQLGQLYPVEYKRGCKGEWDNDELQVCAQALCLEEMTGQPVTNGYIYYAHSHQRQLVEINAELRESAIATIESVTNLLETGAMPKPVYSKRCQGCSLYSQCLPKATDKVKSYQEVN
>NZ_CP046703.1|WP_114082627.1|5750345_5751215_+|CRISPR-associated-endoribonuclease-Cas6
MPHSLVLNLLPQSPIPSQYLTGRHLHALFLTLVSSVDSTLGDRLHDSTADKAFTLSPLQIKGEGIGDRGQDRGKYKSKISTSSSLQYSHQQPIPAGTPCWWRISLLDDTLFSKLTQLWLNLNPNRPWHLGPADLYITSIQGTPQSIQPWANATTYAQLYEEASDRHSSINLTFSTPTAFRQGQYDTTLPTRESVFNSLLSRWNKYSGIELPQITIESIFPSFVNIHTEILADSRSKFIGILGEVNYKILGAIEPIQIKQLNALADFALYAGIGRKTTMGMGMARRLYSP
>NZ_CP046703.1|WP_114082628.1|5749735_5750356_+|2OG-Fe(II)-oxygenase
MKHYQQQTNAFPSDYLNNLWGEIQACPYFAINNLNRDFVATKGFSVVFQRSGLAKVEQQFPYFKPYLDLALQPSCNAFYLNPLQLKEGSRVDPHIDRSLRSYSKTIEPPAVVSVLYVRVPADMEGGELVLRSHKRQLGQIKPQFNTLVYFQGDLIHSVNAVKTPGNRLSLVCEQYSLSDAELQEIPEFTVESRSTQSTTKKRKYAS
>NZ_CP046703.1|WP_114082629.1|5749215_5749626_-|hypothetical-protein
MRIDDYNAAKALTEKLKENLPIKARAGKEFLKTLKQKGVNADPDREFEIDFVGYSGDEGGIMCGLKEPNNPESKEQYVSAITHLKIDPNHSLAAEVQAYQRQRIRKLMLQDSRGFKAELMMIEPRKNKNRGKGFGK
>NZ_CP046703.1|WP_114082630.1|5748507_5749215_+|type-I-D-CRISPR-associated-protein-Cas5/Csc1
MVFISRCQIELHDSLYFATREIGRLYETEPIIHNYALCYALGLVDSQIYSTTVAEEHSYRYFCPEQVPKYEEHLTPLNQQGIYVTPARSLNHSSILNTWKYANNNYHVEMEKTQKNIPSFGRAKEIAAESKFEFFVISQKELKLPKWIRLGKWMSKAEVTVEQLPKHKISEGIFTCTHPLNPLDVMFTNQVISYDVVNMPPVSLIQNVQMRGQYYQFDGIQNLKIPVRVEYRFRS
>NZ_CP046703.1|WP_114082631.1|5747491_5748508_+|type-I-D-CRISPR-associated-protein-Cas7/Csc2
MAILKTVESKFFQTEIPYKPMGKYVHFLTIRITESYPLFQTDAELNKARVRAGVKDKTTISRLSMFKRKQSTPERLVGRELLRNYGLMTAEECEYNVNFAMDNPDCIIYGFAIGDSGSEKSKVVVDTAFSITAFDESHETFTLNAPYENGTMASKGENGSKPGEVTSRINQQDHIRPQVFFPSIVTLKDPTEASFLYVFNNILRTRHYGAQTTRTGRVRNELIGVVFADGEITSNLRWTQAIYDQMKSNNTLNAPDPLDEDDVITAAKNAIEALMADEFIVHTDLIGDAFVSLINEVKTLTGSEKGIQAILQKADAEAKDYAKKHISKKKTAAKAGKE
>NZ_CP046703.1|WP_114082632.1|5744152_5747443_+|type-I-D-CRISPR-associated-protein-Cas10d/Csc3
MSNDDWLSGDFGFDGDSSDRTIETKGELLTLKLLREAIQSQNPDDKVMADFGEYVLPNLLRIAIGVTAKGGKFFDEIDQQREAEGKIKVRRDNAADQSLNTHLLNGLFPANLIEKRLEKLNTTVQRVVKERERRLVIAGFILHDFEKFPDVPENCRKLPLAEHREIIDKKVHQLGLDNFINPENTEAYREYLDDLLCMAYNAQRRWDTNWNFSEFGLNPLLKDRTLRSLSDLTCLADSLASIVKHPQDAEHPRLKEIIHSLSDGQLKFTYHSIAENRGVLTNVVNNALIQAHTSLNTDEYTYYEPLLYLPTGVIYLASRNAPAISPEDLPDRVVNSIKSLCAGQLRLRQTGFGRDGKGMKYAEYYNLFFDDIGLMKVALDATLRILNPNKGSVAKSRSENLNKFQQQNVLSADYDFKFEDDIRIDQIAEFGDLVSRKIWEETVNRVDYARKKDKKLPAVPDFDLTHKVAEFWNLAECLPQIREIQRINESLKENKLKGNTGGVPYEWYYLAAKYLEHHPGIEDVREACQQVIEYLTTLISPIISQYQLPDGWDDLRLWVKRVVMLPGTNQEPSVKTQVETFLNELDNYNAAKKAGRGKQLICSISHSAYTVTEQMESAVLFTPQVYTNKQMLGGSNAKRNISSIAGVEMMLRQILMNQTQAVGKRFEDGKYRYLYFYPTYYFTPETNKFLQKAYNGIAQTRFDTSVRNHFISKDLQANLGRDRYQSVDSFLIDENLQRDKDRTFKLSYPEDQPLTFYFMALPPGRDSTDTESWVMPTWLAFAFPMILDVKTVVSESPIPPFNDGAEFEESVFLDSAPHAFRALVRRDRFRLDYILEGWNENGIQYPAPLNVLTAAYAIHLDVNARQGKSGYDANWGRFTELAKDFETSPLYVFSYLNRWVRNQGSETARIEKIRLYAYHFYPCFDPYVKYDTNMEQLIVGEASSLNHPKKLTDLYRRFYRANKRYNPKSNAVLKPVDIAAETILKAESSVFQGETLVVAVAAEVFKLMDRVHSSTAEGRWIMSKREEERQAVLDFAKYFVVEVFDNAFAGDRARLAGRQLNLIRDTCEFLYRLEDDKENAGKNENIPVIDDVKEPE
>NZ_CP046703.1|WP_114082633.1|5743115_5744135_+|DUF1016-domain-containing-protein
MSNPVSDNYRHLLMEIKQRIRSAQYEALKAVNREMINLYWDIGQIIVTQQQGASWGKSVVEQLAKDLQAEFPGISGFSAANLWRMRLFYESYVNNEKLAPMVREIGWSHNLVIVEKCKDDLEREFYIRMTRKFGWTKNVLIHQIENQTYEKTLLNQTNFDKTVPAEIRNQLKLAVKDEYTFDFLELADEHSERQLEQAILARVEPFLQEMGGRFTFVGSQYRLEVGDKEFFIDLLLYHRQLKCLVAIELKTGEFLPEYVGKMQFYLAALDDLSRFPDENLSIGIILCKSKDKTIVEYALRESNKPIGIATYKLFSTLPQELKNQLPAPEQVAKLLEGVE
>NZ_CP046703.1|WP_114082623.1|5754530_5761151_-|HAMP-domain-containing-protein
MATEQLTRDSDNLDLNQLLRTLNAVKQGDFSARMPIDHTGVAGKIADTLNDIIDQNERMAAELQRIGNVVGKEGKIAERASLGDVRGSWSNCVTSVNTLITDLVQPTAETTRVIRSVANGDLSQTIATEIDGRPLQGEFLQTANIVNTMVDRLGSFASEVTRVAREVGTEGKLGVQAEVQGVAGTWKDLTDNVNLMAGNLTGQVRNIAEVATAIANGDLSKKITVDVKGEILELKNTVNTMVDQLNSFASEVTRVAREVGTEGKLGVQAEVKGVAGTWKDLTDNVNLMAGNLTAQVRNIAEVTTAVANGDLSKKITVDVKGEILELKNTVNIMVDQLNSFASEVTRVAREVGAEGKLGGQAEVRGVAGTWKDLTDSVNFMAGSLTAQVRNIAEVTTAVANGDLSKKITVDVKGEILELKNTINTMVDQLNSFASEVTRVAREVGTEGKLGVQAEVRGVAGTWKDLTDNVNLMAGNLTGQVRNIAEVATAIANGDLSKKITVDVRGEILELKNTINIMVDQLSSFASEVTRVAREVGSEGKLGVQADVRGVAGTWKDLTDSVNFMAGSLTAQVRNIAEVTTAVATGDLSKKITVDVKGEILELKNTINTMVDQLNSFASEVTRVAREVGSEGKLGVQAEVRGVAGTWKDLTDSVNFMAGSLTAQVRNIAEVTTAVATGDLSKKITVDVKGEILELKNTINTMVDQLSSFASEVTRVAREVGTEGKLGVQAEVKDVAGTWKDLTDSVNFMAGSLTAQVRNIAEVTTAIANGDLSKKITVAVKGEILELKNTINIMVDQLNSFASEVTRVAREVGSEGKLGVQADVRGVAGTWKDLTDSVNFMAGSLTAQVRNIAAVTTAVANGDLSKKISVDVKGEILELKNTVNTMVDQLNSFASEVTRVAREVGTEGKLGVQAEVKGVAGTWKDLTDSVNFMAGSLTAQVRNIAEVTTAVANGDLSKKITVDVKGEIQELKNTINTMVDQLNSFASEVTRVAREVGTEGKLGVQAYVRGVAGTWKDLTDNVNSMAGNLTGQVRNIAEVTKAVANGDLSKKITVDAKGEILDLKNTTNTMVDQLSSFASEVTRVAREVGTEGKLGGQAQVQGVAGTWKDLTDNVNSMAGNLTAQVRGIARVVTAVANGDLKRKLMLDAKGEIETLAETINEMIDTLATFANQVTTVAREVGIEGKLGGQARVPGAAGTWKDLTDNVNELAATLTTQLRAIAEVATAVTKGDLTRSIAVEALGEVAILKDNINQMIANLRETTQKNTEQDWLKTNLAKFTRMLQGQRDLETVSKLILSELAPLVGAQHGVFFLMESGENTPFLKLISSYAYRERRHLANRFHLGEGLVGQCALEKERILLTDVPSDYVRIASGLGEATPLNAVVLPVLFEGQVTAVIELASFRRFSEIHLTFFDQLTESIAIVLNTIAASMRTEELLKQSQSLAEELQTQQNELRETNKRLEQQAQSLKTSEDLLKGQQEELQQTNAELEEKAELLAMQKKEVERKNREIEQARMSLEDKAEQLALSSKYKSEFLANMSHELRTPLNSLLILAKLLADNIDHNLTSKQVEYSQTIYSAGTDLLALINDILDLAKIESGTMSIDMTQMPLVELGEQIERTFRQIAQSKGLAFTIEFTPELPTTIYTDVKRLQQVLKNLLSNAFKFTEQGEVRLQIAVAKQGWSNDQVTLNRAQNVIAFSVSDTGIGIAPDKQKVIFEAFQQADGSTSRRYGGTGLGLSISREIARLFGGEIKLTSQPGQGSTFTFFFPQLNPEPTSTQPLTPYSLLPTPHSALSTQHGLNLSYPLTSLINDDRATIGMGDRVLLIVEDDVNFARILIDMAQQHGFKVITAQNGSTGLALAQQFHPSAVLLDIRMPEMDGWTVLDRLKHDPNTRHIPVHIMTVEEGQQRSLQLGAIAYLQKPLSSEIISEALVKIKGFVERQVKNLLVVEDDDTQRHSIVELIGNNDVYTTAVATGAEALEAIRSQHFDCLVLDLGLPDMTGFELIDQIKLLPHGKTLPIIVYTGRDISKAQETELRRIAETIIIKDVRSPERLLDETALFLHRVQANLPAPKRQILEQLHSIDYLLAGKKALIVDDDVRNIFALTSMLERYQIQVLYAENGREGINVLENTPDIDVVLMDVMMPEMDGYETTSLIRQNEQFKSLPIIALTAKAMQGDREKCIEAGASDYITKPVDTEQLLSLLRVWLYR
>NZ_CP046703.1|WP_114082622.1|5761513_5761738_-|hypothetical-protein
MKTQNEIIKQGYDALINSLGVPDTIRFIQYFSPGKGDYTKERHQWLDEKTLADVLVEIKELPEDDTNQYDEIIE
>NZ_CP046703.1|WP_114082621.1|5761721_5762207_-|PIN-domain-containing-protein
MSKQYKIYLDACCLNRPFDDQTQSRIYLEAQAVMTILSQCQSATWKLINSSALIAELNQTPDLERLQNVKKLLDIAKIKVINSTFIEDRAAQLQKLGFSSYDATHIASAERSKADVFLTTDDRLFKKAQKNSQLINVLINNPVQWLAEVIQVEESNDENPK
>NZ_CP046703.1|WP_114082620.1|5762272_5762494_-|type-II-toxin-antitoxin-system-HicB-family-antitoxin
MENSFTAVFEKIDDWYIGYVQELPGANVQERTLEEARESLREAIELILISNRELAEQQLSGKDVVREQITVKL
>NZ_CP046703.1|WP_114082619.1|5762546_5766323_-|magnesium-chelatase-subunit-H
MKRIVLVAGFESFNADLYRKAAFLANSRCPELDIRVFSDRNITSQRAEVEAALDNADVFFGSLLFDYDQVVWLRDRVSQIPIRLVFESALELMSLTKLGDFAIGDKPKGMPKPVKFILDKFSNGREEDKLAGYISFLKIGPKLLKYVPVQKVQDLRNWLIIYGYWNAGGPENVASLFWTLAEKYLNLKVGDIPPLIETPNIGLLHPDYQGFFESPKAYLEWYEKIPPSPPYKGGNISPPSQGGLGGSQATKPVIGILLYRKHVITKLPYIPQLIRSFEEAGLTPLPIFINGVEGHVAVRDLMTTDYEIQQRKLGNIETPSLSSEAVKVDAIVSTIGFPLVGGPAGSMEAGRQIEVAKRILTAKNVPYIVAAPLLIQDIHSWTRQGVGGLQSVVLYALPELDGAIDTIPLGGLVGENIYLVPERVQRLIDRVKSWVSLRQKPASERKIAIILYGFPPGYGAAGTAALLNVPRSLLKFLHALKEQGYTVGDLPDDGEELIRWVKEADEANPLVGQSSRLPLDNGGQDAHPTSTVNFRTLEKWLGYLQTSRIEKQWKSLTGTGIKTSGEEFQIGGVQLGNVWIGVQPPLGIQGDPMRLMFERDLTPHPQYAAYYKWLQNEFQADALVHFGMHGTVEWLPGSPLGNTGYSWSDILLGNLPNLYIYAANNPSESMLAKRRGYGVLISHNVPPYGRAGLYKELVALRDLIAEYREDPQKNYVLKEGICKKIVDSGLDADCPFEDAKKLGIAFTPENVRMFSGHAFDDYLVELYEYLQVLENRLFSSGLHTLGERPSEEELGAYLEAYFGEEEENEPQRRGERREEREEEERLIRDLLMQSTDELTNLLRGLNGEYIPPAPGGDLLRDGAGVLPTGRNIHALDPYRMPSPAAYERGREIGQKIIAQHLDEYGKYPETVAVMLWGLDAIKTKGESLGILLELVGAEPVKEGTGRVVRYELKPLAAVGHPRIDVLGNLSGIFRDSFVNIIELLDDLFQRAADADEPDDQNFVRKHALALKAQGVENASARLFSNPAGDFGSLVNDRVVDGNWESGEELGNTWQSRNVFSYGREDKGQARPEVLNTLLKTSDRIVQEIDSVEYGLTDIQEYYANTGGLKKAAEKQSGKKVTTSFVESFSKDTTPRNLDDLLRMEYRTKLVNPKWAQAMANQGSGGAFEISQRMTALIGWGGTADFTDDWVYDQAADTYALDAEMADKLRKANPEAFRNILGRMLEAHGRGFWEADADKLDKLRQLYELTDEELEGVTV
>NZ_CP046703.1|WP_114082618.1|5767161_5768103_+|cell-wall-hydrolase
MKFGIDSGHNCPPDTGARGIKFEDNLTLDVGNRVIAKLRALGNDVVVCRPSSASTVRDSLSKRCSTANGSKVDIYVSIHFNAFNNQANGTEVFATSETGRRIAKPVLDEIVKLGFFNRGVKSGSHLYVLKNTDMPAILIECCFIDSQKDMNLFNPEAMANAIVKGLTGKVPTTPVNPVPDEEENVDATILRLQKSLNRLKIVDKNGKALVEDGFTGANTKSAVEKFQAIVGVQPTGVADATTWNAINLILAKRIIRPNHAGGAVVRYLQYRLGVENDGVYGPQTEVAIKNFQKQNGLDADGIVGPASWQKLIG
>NZ_CP046703.1|WP_114082617.1|5768366_5769344_+|SDR-family-NAD(P)-dependent-oxidoreductase
MKHLEGRVALVTGATRGIGRGIAIGLAEAGATVYVTGRSLNNSSSDAVSGSLGETQSTIEEAGGVCIPVQVDHSDDEQVRLLFERIQDEQDGQLDLLVNNAYSGVEAIKNAFGQPFWDCELSLWDASNNVGLRSHYVASVFAARMMTKRKSGLICTISSWGSMSYIFNTAYGVGKAACDRLAADMAVELKPHNVASVSIWPGIVGTELFSRFASEMNQTDTTEQKNSFLSDRYNWETPLLTGRVIAALACEPNLMRRTGRVQIVAELADKYGIVDENGDRPASLRSLRFVLPAALPILRNYSWLVPDIKMPWSLLLLSALSSPKI
>NZ_CP046703.1|WP_114082616.1|5769520_5771860_+|sodium:calcium-exchanger
MQEDFRLIVDLVLVLGVAACGGLLAALLRQPVLLGYLIGGMIIGPAGLGLIKEVIQVETLAQFGVAFLLFALGVEFSFAELKKVKAIALGGGGLQIALTILVTVLVCGLSGAWGTLPAKGMFLGCILSLSSTAVVLKCLMERNETETPHGQVMLGILVVQDLALGLMLAVLPALNQPAETIGIAVLTALLWIALFAAGAVGAGMWLIPPLLRLLARTESRELFLLGVVALCLGIALLTEHLGLSIEMGAFVAGLMISEVEYADQTLTYVEPLRDIFASLFFAAIGMLIDPVFLWNNLELILGLVALVFIGKFLIITPLVKLFRYPLKTAIIAGLGLAQIGEFSFVLASEGQSLGLVSRQIYLLILGTTAVTLMLTPFVLRLVPFLFNFAESMPWLKPYLEEQEALDVSEDLPFKDHVVVCGYGRVGKNLVKLLLQHNLPVVVIDQSESRIQQLREAGVSYVYGNCVSLHVLETAGVNHAKGMAIALPDPMSTRLCLKRALELRPELDLVVRATQDKNIEVLYQLGAREVVQPEFEASLEMATYLLTGLGLLSPAVVQREMQLIRNDHYLDLRPERSATEVARDLRQATRDLNQRWYPLPADSPLIGMSIEEADMRYLTGASLMAIRRANGDEIDYPNNQTKLENGDRLLVVGADEELAALAEFAKGQAAVPGENSACQWVTVNADTPTLGKTLADLDINKQFGVQVQAIRRDGKFIRYPDGGMDLRVGDQVLLCGSLTGLSQLEQLFAIANSLPLSLPVLKAAQAEALKEFLPADNVTD
>NZ_CP046703.1|WP_114082615.1|5772247_5772946_+|PEP-CTERM-sorting-domain-containing-protein
MRKITIATFGAISILGIGSIFPELANAATVGISSYDITNTQLSGFGSWNHNYNGIINSNSNGTYNYSDGSGTLNDSFIGTDIDNTHLFLKSDNSTITTFLDQKSAIANIKLFSFGPTENGIPGNIDTVNITINGITENFSTIGFEPEGIPPNNVNGLVNELIDFSNSIFANVVTDKVTFSNFQTSGNFPEYYSISEIVFEQTATSVPEPISLGGIAVAGAMGLWMKRKKKAF
>NZ_CP046703.1|WP_114082614.1|5773124_5778677_-|AAA-family-ATPase
MVENRVDVPGYGIGERIYTSTRTLVYRGWREADQTPVVIKLLKNSYPSVIELAQFRNQYSITKILNVPGVVRIYSLESCQNRPVLILEDFGGISLKEYTVFRRKGLGETGNQENPSSLHPDFLTEFLEIAIALADILADLYHHEIIHKDIKPANILINPTTKQVKIIDFSIASLLPRVNQLSTSPTVLEGTLAYLSPEQTGRMNRGIDYRTDFYSLGVTFYELLTGQLPFQSDDLMELVHCHIAKQPPLLNDRGEIPQILCDIVMKLMAKNAEDRYQSALGLKHDLQICLEQLQSSGNIIPFQLGHRDVCDRFAIPEKLYGREAEVAMLLATFERVRQGTSEMILVAGSSGIGKTAIVNEVHKPITRQRGYFIKGKFDQFNRNIPFFALVQAFRDLMAQLLTESDAQIDQWKTQILSTLGESGQVIIEVIPELERIIGKQPSLPKLSSTAVQSRFNLLFQKFIQVFTTQEHPLVIFLDDLQWADSASLKLMHLLMSEASNSYLLVIGAYRDNEVSSAHPLMLTIEEMRQEAITVSSIVLSALTESDLNQLIADTLKYSTEQATAIANLVYQRTKGNPFFTNQFLKSLHEDGLIAFASRTGDWQCNLVQIRALSFTEDIVEFVAVQLHKLPQQTQNVLKLAACVGNQFDLETLSVVYEKSPVQTAADLWPALKDELILPSGEGYTFFQDESVVMDDLTNDNTPIIITYKFFHDRIQQAAYSLIPDYEKPATHLKIGQLLLSNTPETEQELLIFEIVNQLNIGIELIASQTDRDRLAQLNLLAGKKAKSSTAYQVAIEYLTTGIRLLRSDCWQSQYELTLALHESAADAAYLSGAYEQMEQLTQTVIQQAKTPLDQVGIYETKIQAYTAKNDVLGAIAIARQGMSKFGVVFPETPTPQDIQQALQETATLINGRDIAELLDLPVMVAAEKLAVTRIVANVAPAVYIADPNLFPLLVLSQVQASIEYGNAPFSAFCYGCYGILLSGILQDIETADRVGNLALALTDKFNISDIKPTVFYVVGAFITYLKSPLQKSLQLMLDGYKIALETGNVYYVGFNTKDICQYSYFLGRELNSLEEDIRAYCHVLENFKQGTTLNYCRIFWQTVLNLLGKAENPCIITGEALNEAEFVNQLVQANELTGLHYFFLHKLILCYLFENLSQAVETAAQAREYLVAGTGYATVPMFYFYDSLTALAEYRTAIASRQETLLERVTENQEKMQTWAHHAPMNYLHKFELVKAEECRVLGQMAQAVDHYDRAIAQAKANRYLQEEALANELAARFYLEWNKEAIAQIYLENAYYIYLSWGAIAKVNQLERQYSQLLLKVFQQDETTSSTLTTTIGFNQSSSTGTEALDLATVMKASHTLAGEIELEKLLTTLMQVVIENAGADKSVLLLLQEDNWVVVAQKTSQAIFEEEQFLPHPTPTDENLGIINLHSLPLSASQDVPKAVVNYVSRTTETLVLDDARKETTFANDPYIILWQPKSLLCTPIHNRGQLIGILYLENSLTTGAFTQNRLEVLRLLTAQAAISLQNAMLYNNLAVAKAQLEDYNHTLEQKVEQRTLELNDKNQHLSETLEELQHTQSQLIQTEKMSSLGQMVAGVAHEINNPINFIYGNLTYTNEYCQDLLHLVERYQHYYPQPFPEIQQELEAIDLNFLKPDLQKLLQSMKVGADRIRQIVLSLRNFSRLDEAEMKSVNLHEGIDSTLLILHHRLEEKAHRPGIDVIKEYAQLPEVSCYASQINQVFMNILNNAIDALDSSFTNEERQTKIPTIQIRTKMTDADTVTIQIADNGSGMSDEVKQRLFDPFFTTKPIGTGTGLGLSISHSIVEKHRGRISVISEPGKGAEFSLSIPLH

Crispr_ID: NZ_CP046703_17

• CRISPR_ID: NZ_CP046703_17
• CRISPR_location: 6707883-6709219
• CRISPR_type: Orphan
• Repeat_type: I-D,II-B
• Spacer_info: 18 spacers

Consensus repeat of NZ_CP046703_17

Consensus_repeat	Method
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	CRISPRCasFinder
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	CRT
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	PILER-CR

spacers of NZ_CP046703_17

>17.1|6707920|34|NZ_CP046703|CRISPRCasFinder,CRT
CGTTGATAGCCACACCAGCTAAAAGTGAAGCACT
>17.2|6707991|35|NZ_CP046703|CRISPRCasFinder,CRT
CTGTAATTCCATAGCGATTAATTACTTTTCAGAGT
>17.3|6708063|35|NZ_CP046703|CRISPRCasFinder,CRT
TGTAAAGATTTTCTAATGCCTGTATTGTCAAATCC
>17.4|6708135|34|NZ_CP046703|CRISPRCasFinder,CRT
GGGGCGATCGCTCCGGCACCTTAATTGCTTTGGC
>17.5|6708206|35|NZ_CP046703|CRISPRCasFinder,CRT
TTTTCCTTCAAGCTTACCCAAATGCTACAACAATT
>17.6|6708278|37|NZ_CP046703|CRISPRCasFinder,CRT
GGTATATCAAAGAAGCTTATTGGTCGTTTAAATATTA
>17.7|6708352|33|NZ_CP046703|CRISPRCasFinder,CRT
TAACTACATCTCCATCTTGTGTAGCTGTTATTT
>17.8|6708422|33|NZ_CP046703|CRISPRCasFinder,CRT
TAAAAAGTGTAACGTTTGGTGGTGGTGGAATAA
>17.9|6708492|39|NZ_CP046703|CRISPRCasFinder,CRT
TCAAAGATTGCCCCGCCAAAGTCCCTGATAAATCTAGGC
>17.10|6708568|36|NZ_CP046703|CRISPRCasFinder,CRT
ATGCGCCTTCCTCTACTTTTCCGTATATAGATGCTC
>17.11|6708641|35|NZ_CP046703|CRISPRCasFinder,CRT
CACAGGTAAGTCACCGGATGGTAAGAATGTATACA
>17.12|6708713|36|NZ_CP046703|CRISPRCasFinder,CRT
AATTTATGGGTTCACTATATCAACAACAGCAGTTAC
>17.13|6708786|34|NZ_CP046703|CRISPRCasFinder,CRT
CCAAAGTTGGTCTGTGGTAGAGCTATATAATCAG
>17.14|6708857|35|NZ_CP046703|CRISPRCasFinder,CRT
TTGATACAGCCTGCTTAGGTTACTGCAATTTCCTT
>17.15|6708929|37|NZ_CP046703|CRISPRCasFinder,CRT
TTTTCGTGGCGTTTCATCATATCCAATGACGACCAAA
>17.16|6709003|33|NZ_CP046703|CRISPRCasFinder,CRT
GCCACAATCAAAGGTAATAGAGGAGAAATTCAA
>17.17|6709073|37|NZ_CP046703|CRISPRCasFinder,CRT
GGGGACATTGTGATGGAGGAGCGATCGCATCTGCAAC
>17.18|6709147|36|NZ_CP046703|CRISPRCasFinder,CRT
TAGAAGTGGTGGCGATATCGCGCCTCCCCAAATCGA
>17.19|6707921|34|NZ_CP046703|PILER-CR
CGTTGATAGCCACACCAGCTAAAAGTGAAGCACT
>17.20|6707992|35|NZ_CP046703|PILER-CR
CTGTAATTCCATAGCGATTAATTACTTTTCAGAGT
>17.21|6708064|35|NZ_CP046703|PILER-CR
TGTAAAGATTTTCTAATGCCTGTATTGTCAAATCC
>17.22|6708136|34|NZ_CP046703|PILER-CR
GGGGCGATCGCTCCGGCACCTTAATTGCTTTGGC
>17.23|6708207|35|NZ_CP046703|PILER-CR
TTTTCCTTCAAGCTTACCCAAATGCTACAACAATT
>17.24|6708279|37|NZ_CP046703|PILER-CR
GGTATATCAAAGAAGCTTATTGGTCGTTTAAATATTA
>17.25|6708353|33|NZ_CP046703|PILER-CR
TAACTACATCTCCATCTTGTGTAGCTGTTATTT
>17.26|6708423|33|NZ_CP046703|PILER-CR
TAAAAAGTGTAACGTTTGGTGGTGGTGGAATAA
>17.27|6708493|39|NZ_CP046703|PILER-CR
TCAAAGATTGCCCCGCCAAAGTCCCTGATAAATCTAGGC
>17.28|6708569|36|NZ_CP046703|PILER-CR
ATGCGCCTTCCTCTACTTTTCCGTATATAGATGCTC
>17.29|6708642|35|NZ_CP046703|PILER-CR
CACAGGTAAGTCACCGGATGGTAAGAATGTATACA
>17.30|6708714|36|NZ_CP046703|PILER-CR
AATTTATGGGTTCACTATATCAACAACAGCAGTTAC
>17.31|6708787|34|NZ_CP046703|PILER-CR
CCAAAGTTGGTCTGTGGTAGAGCTATATAATCAG
>17.32|6708858|35|NZ_CP046703|PILER-CR
TTGATACAGCCTGCTTAGGTTACTGCAATTTCCTT
>17.33|6708930|37|NZ_CP046703|PILER-CR
TTTTCGTGGCGTTTCATCATATCCAATGACGACCAAA
>17.34|6709004|33|NZ_CP046703|PILER-CR
GCCACAATCAAAGGTAATAGAGGAGAAATTCAA
>17.35|6709074|37|NZ_CP046703|PILER-CR
GGGGACATTGTGATGGAGGAGCGATCGCATCTGCAAC
>17.36|6709148|36|NZ_CP046703|PILER-CR
TAGAAGTGGTGGCGATATCGCGCCTCCCCAAATCGA

CRISPR arrays and Neighbor proteins around NZ_CP046703_17

CRISPR arrays

The CRISPR arrays of NZ_CP046703_17

>merge|NZ_CP046703|17|6707883-6709219|CRISPRCasFinder,CRT,PILER-CR
CTTTAAATCCCTAGTAGGGATTTTGATAAATTGCAATCGTTGATAGCCACACCAGCTAAAAGTGAAGCACTGTTTCAATCCCTAATAGGGATTTTGATAAATTGCAATCTGTAATTCCATAGCGATTAATTACTTTTCAGAGTGTTTCAATCCCTAATAGGGATTTTGATAAATTGCAATTGTAAAGATTTTCTAATGCCTGTATTGTCAAATCCGTTTCAATCCCTAATAGGGATTTTGATAAATTGCAATGGGGCGATCGCTCCGGCACCTTAATTGCTTTGGCGTTTCAATCCCTAATAGGGATTTTGATAAATTGCAATTTTTCCTTCAAGCTTACCCAAATGCTACAACAATTGTTTCAATCCCTAATAGGGATTTTGATAAATTGCAATGGTATATCAAAGAAGCTTATTGGTCGTTTAAATATTAGTTTCAATCCCTAATAGGGATTTTGATAAATTGCAATTAACTACATCTCCATCTTGTGTAGCTGTTATTTGTTTCAATCCCTAATAGGGATTTTGATAAATTGCAATTAAAAAGTGTAACGTTTGGTGGTGGTGGAATAAGTTTCAATCCCTAATAGGGATTTTGATAAATTGCAATTCAAAGATTGCCCCGCCAAAGTCCCTGATAAATCTAGGCGTTTCAATCCCTAATAGGGATTTTGATAAATTGCAATATGCGCCTTCCTCTACTTTTCCGTATATAGATGCTCGTTTCAATCCCTAATAGGGATTTTGATAAATTGCAATCACAGGTAAGTCACCGGATGGTAAGAATGTATACAGTTTCAATCCCTAATAGGGATTTTGATAAATTGCAATAATTTATGGGTTCACTATATCAACAACAGCAGTTACGTTTCAATCCCTAATAGGGATTTTGATAAATTGCAATCCAAAGTTGGTCTGTGGTAGAGCTATATAATCAGGTTTCAATCCCTAATAGGGATTTTGATAAATTGCAATTTGATACAGCCTGCTTAGGTTACTGCAATTTCCTTGTTTCAATCCCTAATAGGGATTTTGATAAATTGCAATTTTTCGTGGCGTTTCATCATATCCAATGACGACCAAAGTTTCAATCCCTAATAGGGATTTTGATAAATTGCAATGCCACAATCAAAGGTAATAGAGGAGAAATTCAAGTTTCAATCCCTAATAGGGATTTTGATAAATTGCAATGGGGACATTGTGATGGAGGAGCGATCGCATCTGCAACGTTTCAATCCCTAATAGGGATTTTGATAAATTGCAATTAGAAGTGGTGGCGATATCGCGCCTCCCCAAATCGAGTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT

>NZ_CP046703|17|15|6707883-6709219|CRISPRCasFinder
CTTTAAATCCCTAGTAGGGATTTTGATAAATTGCAAT	CGTTGATAGCCACACCAGCTAAAAGTGAAGCACT
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	CTGTAATTCCATAGCGATTAATTACTTTTCAGAGT
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	TGTAAAGATTTTCTAATGCCTGTATTGTCAAATCC
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	GGGGCGATCGCTCCGGCACCTTAATTGCTTTGGC
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	TTTTCCTTCAAGCTTACCCAAATGCTACAACAATT
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	GGTATATCAAAGAAGCTTATTGGTCGTTTAAATATTA
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	TAACTACATCTCCATCTTGTGTAGCTGTTATTT
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	TAAAAAGTGTAACGTTTGGTGGTGGTGGAATAA
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	TCAAAGATTGCCCCGCCAAAGTCCCTGATAAATCTAGGC
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	ATGCGCCTTCCTCTACTTTTCCGTATATAGATGCTC
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	CACAGGTAAGTCACCGGATGGTAAGAATGTATACA
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	AATTTATGGGTTCACTATATCAACAACAGCAGTTAC
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	CCAAAGTTGGTCTGTGGTAGAGCTATATAATCAG
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	TTGATACAGCCTGCTTAGGTTACTGCAATTTCCTT
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	TTTTCGTGGCGTTTCATCATATCCAATGACGACCAAA
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	GCCACAATCAAAGGTAATAGAGGAGAAATTCAA
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	GGGGACATTGTGATGGAGGAGCGATCGCATCTGCAAC
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	TAGAAGTGGTGGCGATATCGCGCCTCCCCAAATCGA
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT

>NZ_CP046703|17|6|6707883-6709219|CRT
CTTTAAATCCCTAGTAGGGATTTTGATAAATTGCAAT	CGTTGATAGCCACACCAGCTAAAAGTGAAGCACT
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	CTGTAATTCCATAGCGATTAATTACTTTTCAGAGT
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	TGTAAAGATTTTCTAATGCCTGTATTGTCAAATCC
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	GGGGCGATCGCTCCGGCACCTTAATTGCTTTGGC
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	TTTTCCTTCAAGCTTACCCAAATGCTACAACAATT
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	GGTATATCAAAGAAGCTTATTGGTCGTTTAAATATTA
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	TAACTACATCTCCATCTTGTGTAGCTGTTATTT
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	TAAAAAGTGTAACGTTTGGTGGTGGTGGAATAA
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	TCAAAGATTGCCCCGCCAAAGTCCCTGATAAATCTAGGC
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	ATGCGCCTTCCTCTACTTTTCCGTATATAGATGCTC
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	CACAGGTAAGTCACCGGATGGTAAGAATGTATACA
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	AATTTATGGGTTCACTATATCAACAACAGCAGTTAC
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	CCAAAGTTGGTCTGTGGTAGAGCTATATAATCAG
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	TTGATACAGCCTGCTTAGGTTACTGCAATTTCCTT
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	TTTTCGTGGCGTTTCATCATATCCAATGACGACCAAA
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	GCCACAATCAAAGGTAATAGAGGAGAAATTCAA
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	GGGGACATTGTGATGGAGGAGCGATCGCATCTGCAAC
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT	TAGAAGTGGTGGCGATATCGCGCCTCCCCAAATCGA
GTTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT

>NZ_CP046703|17|5|6707884-6709219|PILER-CR
TTTAAATCCCTAGTAGGGATTTTGATAAATTGCAATC	GTTGATAGCCACACCAGCTAAAAGTGAAGCACTG
TTTCAATCCCTAATAGGGATTTTGATAAATTGCAATC	TGTAATTCCATAGCGATTAATTACTTTTCAGAGTG
TTTCAATCCCTAATAGGGATTTTGATAAATTGCAATT	GTAAAGATTTTCTAATGCCTGTATTGTCAAATCCG
TTTCAATCCCTAATAGGGATTTTGATAAATTGCAATG	GGGCGATCGCTCCGGCACCTTAATTGCTTTGGCG
TTTCAATCCCTAATAGGGATTTTGATAAATTGCAATT	TTTCCTTCAAGCTTACCCAAATGCTACAACAATTG
TTTCAATCCCTAATAGGGATTTTGATAAATTGCAATG	GTATATCAAAGAAGCTTATTGGTCGTTTAAATATTAG
TTTCAATCCCTAATAGGGATTTTGATAAATTGCAATT	AACTACATCTCCATCTTGTGTAGCTGTTATTTG
TTTCAATCCCTAATAGGGATTTTGATAAATTGCAATT	AAAAAGTGTAACGTTTGGTGGTGGTGGAATAAG
TTTCAATCCCTAATAGGGATTTTGATAAATTGCAATT	CAAAGATTGCCCCGCCAAAGTCCCTGATAAATCTAGGCG
TTTCAATCCCTAATAGGGATTTTGATAAATTGCAATA	TGCGCCTTCCTCTACTTTTCCGTATATAGATGCTCG
TTTCAATCCCTAATAGGGATTTTGATAAATTGCAATC	ACAGGTAAGTCACCGGATGGTAAGAATGTATACAG
TTTCAATCCCTAATAGGGATTTTGATAAATTGCAATA	ATTTATGGGTTCACTATATCAACAACAGCAGTTACG
TTTCAATCCCTAATAGGGATTTTGATAAATTGCAATC	CAAAGTTGGTCTGTGGTAGAGCTATATAATCAGG
TTTCAATCCCTAATAGGGATTTTGATAAATTGCAATT	TGATACAGCCTGCTTAGGTTACTGCAATTTCCTTG
TTTCAATCCCTAATAGGGATTTTGATAAATTGCAATT	TTTCGTGGCGTTTCATCATATCCAATGACGACCAAAG
TTTCAATCCCTAATAGGGATTTTGATAAATTGCAATG	CCACAATCAAAGGTAATAGAGGAGAAATTCAAG
TTTCAATCCCTAATAGGGATTTTGATAAATTGCAATG	GGGACATTGTGATGGAGGAGCGATCGCATCTGCAACG
TTTCAATCCCTAATAGGGATTTTGATAAATTGCAATT	AGAAGTGGTGGCGATATCGCGCCTCCCCAAATCGAG
TTTCAATCCCTAATAGGGATTTTGATAAATTGCAAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046703.1|WP_114082284.1|6699010_6699505_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114082280.1|6703098_6703539_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114082283.1|6699587_6700253_+|DnaJ-domain-containing-protein	unknown	unknown	gnl|CDD|224276
NZ_CP046703.1|WP_114084108.1|6717624_6718485_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224041
NZ_CP046703.1|WP_114084105.1|6714768_6714972_+|high-light-inducible-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114084106.1|6715160_6716498_-|transporter	unknown	unknown	gnl|CDD|238536
NZ_CP046703.1|WP_114084100.1|6706572_6706827_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114084102.1|6709707_6710541_+|dienelactone-hydrolase-family-protein	unknown	unknown	gnl|CDD|223489
NZ_CP046703.1|WP_114084107.1|6716611_6717229_-|universal-stress-protein	unknown	unknown	gnl|CDD|366180
NZ_CP046703.1|WP_159402594.1|6696937_6697075_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114082282.1|6701098_6701704_+|DUF4360-domain-containing-protein	unknown	unknown	gnl|CDD|372992
NZ_CP046703.1|WP_159402591.1|6703725_6705036_-|IS701-family-transposase	unknown	unknown	gnl|CDD|227946
NZ_CP046703.1|WP_114084110.1|6721699_6722890_+|sensor-histidine-kinase	unknown	unknown	gnl|CDD|223715
NZ_CP046703.1|WP_114084109.1|6718592_6720035_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270271
NZ_CP046703.1|WP_114084141.1|6720121_6720970_-|nitrate-ABC-transporter-permease	unknown	unknown	gnl|CDD|130251
NZ_CP046703.1|WP_114084103.1|6710766_6713886_-|MFS-transporter	unknown	unknown	gnl|CDD|226167
NZ_CP046703.1|WP_114084104.1|6714513_6714726_+|high-light-inducible-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114082281.1|6701955_6702813_+|DUF72-domain-containing-protein	unknown	unknown	gnl|CDD|224714
NZ_CP046703.1|WP_114082285.1|6697225_6698098_-|3-deoxy-7-phosphoheptulonate-synthase	unknown	unknown	gnl|CDD|184028
NZ_CP046703.1|WP_114084101.1|6706935_6707829_+|nitrogenase-iron-protein	unknown	unknown	gnl|CDD|237312

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046703.1|WP_114082283.1|6699587_6700253_+|DnaJ-domain-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	1.60344e-27
NZ_CP046703.1|WP_114084108.1|6717624_6718485_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224041	COG1116, TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism].	7.1105e-127
NZ_CP046703.1|WP_114084109.1|6718592_6720035_-|ABC-transporter-substrate-binding-protein	gnl|CDD|270271	cd13553, PBP2_NrtA_CpmA_like, Substrate binding domain of ABC-type nitrate/bicarbonate transporters, a member of the type 2 periplasmic binding fold superfamily. This subfamily includes nitrate (NrtA) and bicarbonate (CmpA) receptors. These domains are found in eubacterial perisplamic-binding proteins that serve as initial receptors in the ABC transport of bicarbonate, nitrate, taurine, or a wide range of aliphatic sulfonates, while other closest homologs are involved in thiamine (vitamin B1) biosynthetic pathway and desulfurization (DszB). After binding their ligand with high affinity, they interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. These binding proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	9.06966e-69
NZ_CP046703.1|WP_114084106.1|6715160_6716498_-|transporter	gnl|CDD|238536	cd01116, P_permease, Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible for classic phenotype of oculocutaneous albinism type 2 (OCA2). Although the precise function of the P protein is unknown, it was predicted to regulate the intraorganelle pH, together with the ATP-driven proton pump. It shows significant sequence similarity to the Na+/H+ antiporter NhaD from Vibrio parahaemolyticus. Both proteins belong to ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease contains 8-13 transmembrane domains.	2.57841e-100
NZ_CP046703.1|WP_114084102.1|6709707_6710541_+|dienelactone-hydrolase-family-protein	gnl|CDD|223489	COG0412, COG0412, Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism].	1.79887e-76
NZ_CP046703.1|WP_114084107.1|6716611_6717229_-|universal-stress-protein	gnl|CDD|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	9.66893e-07
NZ_CP046703.1|WP_114082282.1|6701098_6701704_+|DUF4360-domain-containing-protein	gnl|CDD|372992	pfam14273, DUF4360, Domain of unknown function (DUF4360). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 200 and 228 amino acids in length. There is a conserved GCP sequence motif near the N-terminus.	3.54572e-58
NZ_CP046703.1|WP_159402591.1|6703725_6705036_-|IS701-family-transposase	gnl|CDD|227946	COG5659, COG5659, FOG: Transposase [DNA replication, recombination, and repair].	6.49353e-90
NZ_CP046703.1|WP_114084110.1|6721699_6722890_+|sensor-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.14701e-51
NZ_CP046703.1|WP_114084141.1|6720121_6720970_-|nitrate-ABC-transporter-permease	gnl|CDD|130251	TIGR01183, Nitrate_transport_permease_protein_NrtB, nitrate ABC transporter, permease protein. This model describes the nitrate transport permease in bacteria. This is gene product of ntrB. The nitrate transport permease is the integral membrane component of the nitrate transport system and belongs to the ATP-binding cassette (ABC) superfamily. At least in photosynthetic bacteria nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA, ntrB, ntrC, ntrD, narB. Functionally ntrC and ntrD resemble the ATP binding components of the binding protein-dependent transport systems. Mutational studies have shown that ntrB and ntrC are mandatory for nitrate accumulation. Nitrate reductase is encoded by narB. [Transport and binding proteins, Anions].	7.61042e-69
NZ_CP046703.1|WP_114084103.1|6710766_6713886_-|MFS-transporter	gnl|CDD|226167	COG3641, PfoR, Predicted membrane protein, putative toxin regulator [General function prediction only].	1.85066e-06
NZ_CP046703.1|WP_114082281.1|6701955_6702813_+|DUF72-domain-containing-protein	gnl|CDD|224714	COG1801, COG1801, Uncharacterized conserved protein [Function unknown].	7.74465e-77
NZ_CP046703.1|WP_114082285.1|6697225_6698098_-|3-deoxy-7-phosphoheptulonate-synthase	gnl|CDD|184028	PRK13398, PRK13398, 3-deoxy-7-phosphoheptulonate synthase; Provisional.	1.76278e-173
NZ_CP046703.1|WP_114084101.1|6706935_6707829_+|nitrogenase-iron-protein	gnl|CDD|237312	PRK13236, PRK13236, nitrogenase reductase; Reviewed.	0

Protein sequences

>NZ_CP046703.1|WP_114084101.1|6706935_6707829_+|nitrogenase-iron-protein
MADEKIRQIAFYGKGGIGKSTTSQNTLAAMAEMGQRILIVGCDPKADSTRLMLHSKAQTSVLQLAAERGAVEDIELEEVMLTGFRDVRCVESGGPEPGVGCAGRGIITAINFLEENGAYKDVDFVSYDVLGDVVCGGFAMPIREGKAQEIYIVTSGEMMAMYAANNIARGVLKYAHTGGVRLGGLICNSRNVDREIDLIETLAKRLNTQMIHYVPRDNIVQHAELRRMTVNEYAPDSNQSNEYRTLATKIINNDKLTVPTPIEMEELEELLIEFGILESDENTAMLVGKSATEAPVK
>NZ_CP046703.1|WP_114084100.1|6706572_6706827_-|hypothetical-protein
MSLDIAPRQKQPKSEHIYPQSDSLSDRKSLSPNNEVFKTLTSALSVVVTESQMVAQASRVVAAGIQTNADLFPEPHNQPNCNPL
>NZ_CP046703.1|WP_159402591.1|6703725_6705036_-|IS701-family-transposase
MVQPRPAAPTVKFVDEYCQWYKSLFPDVRSFEAFKYLHVGCISELKRKTLPEIAKIVGLDNQQGLHHFLTTSPWDIEKLRDLRLELILQVLKGRPIILIIDETGDKKKGNKTDYVKRQYIGNLGKVENGIVAVTAYGVFCGMTFPLLFEIYKPRERLKPEDKYLTKPQIAAILMRKLKSMGFKFNLVLADSLYGESGTNFISVLDEMNLNYIVAIRSNHDVDLLPRQYTQYLKWHKFKRVFSDLSSENRFIREIIHGKRSENRYWQITTDREKLPGNTTWYVMSKYPDLTPRDVGNFYGLRTWVEYGLKQSKNELGWSDYRLTHYPDIERWWEIVCSSYLMVSLHSEQIQSSVPKSPSKLASHPWWNDEKGWKNILNNLRLIIQPFTLFNLIYPWLTVFPIPQLSLGFSKLQSIIYSLTSSIFISLTHPDFYFSSA
>NZ_CP046703.1|WP_114082280.1|6703098_6703539_+|hypothetical-protein
MSRLLYESSVSYKGYLIIPFVFGKVDNYEIYSYKLLSEIGHRSQFHKAENPAKIYGSSVSNIIDIAKEHIDQNSDFVNQRDYFKSRYIYRNHLIIIFQEGDKCFYDHYPPELLNNIAAPKLFKSEYECLSWIKQGLDGPQVRQRAI
>NZ_CP046703.1|WP_114082281.1|6701955_6702813_+|DUF72-domain-containing-protein
MNFFIGCAVWAYKGWVGELYPQGTRTADFLNLYSRRFTTVEGNTTFYAVPNQQTVTRWAAETPAGFEFCLKLPRDITHQGLLQPYIPAALKFLEGMRPLGKHLGPIFAQLPPSYAPALLEDLTSFLEAWPRTDAPLALEVRHPDWFREPHASNLTALLQKLGVGRVLLDSRPIYTGDDDPQLQSERRKPKLPLQLSVTAPFTLIRFISHPNLSVNQPFMEEWVKQIQQWLQAGVRIYFFVHCPIEARSPNIVRHFQQLLEQSDTPVPPLPWNNLEHPPNQLSLWS
>NZ_CP046703.1|WP_114082282.1|6701098_6701704_+|DUF4360-domain-containing-protein
MNNQNLKTTSINFIKSFLAAATLITASVGPAFANDKVEIVGAEYGGNGCPEGSASVSVSPDGQELSILFDKFIAVGNKAEERRKNCNLSIPIKVPQGFQISLYDADYRGYVAPSTIGRLRAEYFFAGQRGPVFSRTFNGESDYNVRDQLVTVADVWSRCGDSVNMRVNAAMTASGQGMATVDSFDLAHRGLVYHVKYRQCR
>NZ_CP046703.1|WP_114082283.1|6699587_6700253_+|DnaJ-domain-containing-protein
MSDLERYYRILELEPGATLEEVNQAYKDLVFVWHPDRIPKENLRLQQKAQDKLKAINEAREKLRSLKTKHQTISNSPSPSPSPSYQQQTPFQKTQPPPKQNSDLSGKDYSRANLSNKDLSGRNLSYANLSGANLSDTFMHKVNLRGANLSEANLFRANLLLADLREANLRGANLIGADLSGTDLRGADLTGARIRSGERLLVKLIGANLAGAIMPDGEIYQ
>NZ_CP046703.1|WP_114082284.1|6699010_6699505_+|hypothetical-protein
MPSSKILAQSFDYYGVYPCPVCRIGKISHMPLMEAMACDFCQEIFTVNLEIQQIKMPSRQPPLTWRWNGFSWTEGQLEGVELGWGYGLAAAVFVILPTTLIGIVAYYFPADLKEPITWTPYIWTVLTFVSHLSIIVWIVIEIYQIPVAAYLRAIARWRNREMER
>NZ_CP046703.1|WP_114082285.1|6697225_6698098_-|3-deoxy-7-phosphoheptulonate-synthase
MINAKLAAQSHPNHQTIVKISEKVAFGGEELVIIGGPCTVESLEQMEIVAQKLSTTSIQGLRGGVYKPRTSPYAFQGMGEEGLRILARVRSHYNMPVVTEVMSISQIEVVAAHADMLQVGSRNMQNFDLLKALGQAGKPILLKRGLAATIEEFVMAAEYILSHGNPDVVLCERGIRSFDDYTRNVLDLAAVAALKQITHLPVIVDPSHAVGKRELVAPVARAAIACGADGLIIECHPEPEKSVSDARQALSLEDMVRLVDSLKPVAKAVGRNISSNVGAGLSPAPIFCAA
>NZ_CP046703.1|WP_159402594.1|6696937_6697075_+|hypothetical-protein
MTLFVSELTQNISQIPIPLHLCDSLRQGADAPSLRDAARTSLPLR
>NZ_CP046703.1|WP_114084102.1|6709707_6710541_+|dienelactone-hydrolase-family-protein
MKEITRRKFIATSTLATGFALAVQPISAQVTATDAKGLVAGAVKIPVKDGEIPAYRAAPATGENFPIVLVIQEIFGVHEHIQDVTRRFAQLGYLAIAPELFIRQGDVTKLSSIDEIRPIVSKVPDSQVLSDLDATVKWAVKSAKGNANKLAITGFCWGGRITWLYAAHNPKVKAGVAWYGRLVGDATELQPKYPIDIASKLTVPILGLYGGKDTGIPLNTVEQMRDRLKSSSSKSEIIVYPDAPHAFFADYRPSYREKDAKDGWKRLLAWFKKYGVS
>NZ_CP046703.1|WP_114084103.1|6710766_6713886_-|MFS-transporter
MFQSTEIMLGLYKPLLWLAQIPVDPSNVTPAQASVLTSGPRFFVALISGVILAFAFQLVLTNLSLAAGISYLGHSSDSDSDSGEVGSLGGSIRKIGTAVGIWTLFTVTIALLIACFLAVKLSLVILDPGLGAILGLVIWGAYFLLLVWVSSTTVGSLIGSVVNTATSGFQAIMGTATAALGAKAVNNQVVATAEAAAAAIRRELGSGIDPGSIRENIEDYLDKLRPPELDVSKIRSDFENLLNDPQLKAIAGTPDIRNIDRQKFIELVSSRTDLSKKDVTRIADTLYKVWQQVVSQHSPTEDRMGELMDYLKSLPAGQSKTDELNAKLDRLVAETRGSKEADQKASTTGPIQSTIQQGLSALTGIVLGRADLSDLDVEKILGSLTTAKDKVTQQADKLGLPTPSQPYSPIRSDVENYLYNTYAWQLSPEKIAQEFRDVIYDPAADPGIVRRELERLSRNDFVKILQQRGLLTQSQIQRIADRLEVVRKDVLVTVTGIEEREIVQDLQRAVESYLLVTPKTDLTPEGIERNFKPLLQDPDADYETLTLRLAHIERQEIREILLERNDVQLYEVDSILDELEKQRDRVLIESKGLAEQAQYQAETLWLNVESYLRNTGKSELNPDAIRAEFKKLLEDPQAGISSIRARLSRFDRDTLVQLLSQRQDLSEDQVNQIINAAEESWHNIRHTPQAVVDKAKEQYDSVTTTIADYLRNTGKQELNPEGIQRDLSKLFENPKEGASALRHRLSQLDRDTLVKLLSQRQDLSEQQVNEIIDSTQTSIRNFIRAPRRLATRTQQRAETFKAYLEEYLRQTGKEELNPEGIKRDLQLLLHDPRVGVESFSDRLSHFDRDTIIALLKIREDMSDEEAARIADNMVSVRDQFVEQVRNIQRGIQDAIDGVFARIRNYLNSLDRPELNYDSIKGDVRTFFDDPQAGFDALRDRLSSFDRETLVAIMSSREDISEEDANRIIDQIERARNTVLQRAERIQQEAQRRLEQVKHQAQRQAEETRKAAATAAWWLFATASVSAVFSALGGALAARP
>NZ_CP046703.1|WP_114084104.1|6714513_6714726_+|high-light-inducible-protein
MATQETRSSTDLPPVAPEYNGIDRNAFLFGWTPQAEIWNGRLAAIGFLAYLLWDLAGYSVLRDVLHLVGY
>NZ_CP046703.1|WP_114084105.1|6714768_6714972_+|high-light-inducible-protein
MEPRSSTDLAPVAKAYNGVDRNAFLFGWTPQAEIWNGRLAAIGFLAYLLWDLAGYSVLRDVLHIISY
>NZ_CP046703.1|WP_114084106.1|6715160_6716498_-|transporter
MDNWQAILSVITFISVIILVMTEWVHLTIAALLGALLLVFTNVMTLEEAVGYIGNSHGTLGLFFGVMVLVRAFEPTKIFDYLATQIVLLAKGQGKRLLLGIVAIVTPICAVLPNATTVMLLAPLIPPMAKEVGINFVPLLILMVFVANSAGLLTLVGDPATFIVGDAVNISFTDYLFKLSLGGVIAVAIVIATLPFLFRKIWNTQLDNLEELPHPQINHPRALSFGAVIVFFVLLFFVVGETLPVPVSPAAAALLGAALALLLSHHSRIDSVNNILRDVDWSTLIFFMSIFVLIGGLEKTGVINGLSGILAAILGKNIILGSLVLLFFVGILSSVIPNIPLVVGMVPLLKQYIVTVGLAPAEVLAQDFQGQFPPEVLPLFYAMMFGATLGGNGTLVGASSNIVAAGISEQHGRRISFKTFLHYGIPVMLLQLVASALYVLFRFLL
>NZ_CP046703.1|WP_114084107.1|6716611_6717229_-|universal-stress-protein
MLARLQSATGRNDLIEQMVLVPEPRKPFSKEPQKAKAVNLIVAYDASPNSHTALDIAFWIAHQTRLATNAEVTVQAVYVVEDNQSSQYPNILSFPQQTSLECQISEVSKSVTQVLTQPKLQTVVTPLQQADIILWQARSLAEEWQGSFKSHLRFGSISTELHKVVESEAADILFLGCQSVNHPMIEALGYNFPCAVLGIPSCIDE
>NZ_CP046703.1|WP_114084108.1|6717624_6718485_-|ABC-transporter-ATP-binding-protein
MEYTSLPINTQTGVLPRTGFLEIENLVKSYPTPDKDNFVVLDGVNLTIGEDEYISVIGHSGCGKSTLLKIVAGLEKATSGSVRLDGKEIRQPGAERMMVFQNYSLLPWLTVRENIRLAVDEVLKNANRAEKISIVNEHLAMVNLTAAADKYPDEISGGMKQRVGIARALAIRPKMLLMDEPFGALDALTRGKLQRQVLDIWENNRQAVMMITHDVDEAIYMSDRIVLMTNGPSASIGEILEVPFEHPRVSKAPLEEARAAMRNSKEYFELRNHALNFLDRYFAQDE
>NZ_CP046703.1|WP_114084109.1|6718592_6720035_-|ABC-transporter-substrate-binding-protein
MGDINWTRRDFIKGIGATTTGIALSSCGISGDRSAKGLTEEALAVQPVVRSQDLEKSDLTIGYVPVNDCAPFAIAWKKGFFHKYGLNVTLNREASWATSRDGLIFGRLDASPVVSGAVTNARIGAEGARHASLCAAMTIHRHGNAMTMNKAMWDFGLRPWYEYQEKYGDGALEAFGRDFRGYFDKQPPEGKVWAVVLSSSIYEYFIRYLSAAAGVDPLKEFRVIIVPPPQMVTNVRIGAMQAYMVAEPWNTRAITGNENIGFTFAQGKEVWLGHPDRLLGVMESFIDKYPKTYRSLVKAMIEACQYCSKAENRQEVAELLTERSFTGARPKNKDAPIAKYTSPGILGNYNYGGFDGKDRTIQAADTTIFFDIPDNLPKQPEEHSTFLWQSRSLWLMTQAARWGQIKEFPKNADKLAQQGWRTDLYREIASEMGIKCPKDDYKVEPPEVFIDKKGFDPSDPVGYLNSFAIRANAPTNFFMS
>NZ_CP046703.1|WP_114084141.1|6720121_6720970_-|nitrate-ABC-transporter-permease
MFQLNLVAIAAIATQAAWKKTKPVILRDVFILPVLGFLGIIVLWWIIALANDELMPTPPEALIANLDYILNPFYQRGPGNLGIGWLLIASLRRVLLGFLLGAVVAIPVGFLIGMSRPAMLALNPIIQIFKPVSPLAWLPIALAIFNLADPSAIFVIFITSLWPTIINTALGVSSVPKDYLDVAQVLEMHRWRRITKIIWPASLPYIFTGLRISLGIAWLVIVAVEMLTGGIGIGFFVWDEWSRLNLSSVFLAVFIIGLTGLILDYAVGKLEELVTHRPKTSN
>NZ_CP046703.1|WP_114084110.1|6721699_6722890_+|sensor-histidine-kinase
MDFSQVLAEKTDTILDKWVTAVRKDRRIESADDLSYTAVKDHVPDVLQAMVTVLSKSQENDIESIVTASFQHGAIRAEQGFDPAEIAREYHLLRTVIFDALQADLLEGTPVDIIRSMRLIDAIIDEAIARCFKSYVEERLRELQQLQLSLTLHNEELTRLMSANQEYLSQLAHELKHPLTSIIGYSDLFLRQQRRKTQIKDTSANLEHIERVLRNGRQLLHLINDVLELSRYEAGQIKLQLAPTDVSELINNICEMLEPLAVGKNLKVVVDCDRAPKELITDPFQCQQIITNLISNAIRYTESGTIIIMCQVLENQRWAIAVSDTGIGIAPENQAQIFEPYFRVSFSDRPYLPDSTGLGLAIVSRLVKLLQGTINLVSEVGVGSTFTVIFPLQIES

Crispr_ID: NZ_CP046703_18

• CRISPR_ID: NZ_CP046703_18
• CRISPR_location: 7120544-7120796
• CRISPR_type: Orphan
• Repeat_type: I-D,II-B
• Spacer_info: 3 spacers

Consensus repeat of NZ_CP046703_18

Consensus_repeat	Method
ATTGCAATTATCTTAAATCCCTATTAGGG----------ATTGAAAC	PILER-CR
ATTGCAATTATCTTAAATCCCTATTAGGGATTG	CRISPRCasFinder
ATTGCAATTATCTTAAATCCCTATTAGGGATTGAAACAA	CRT

spacers of NZ_CP046703_18

>18.1|7120581|34|NZ_CP046703|PILER-CR
AAGCATTATGGTTGCTGGTTTGTAGCGATTTAAT
>18.2|7120652|35|NZ_CP046703|PILER-CR
AAAGCATTATCAACAATTTCACCATCAATTGTCAC
>18.3|7120577|38|NZ_CP046703|CRISPRCasFinder
AAACAAGCATTATGGTTGCTGGTTTGTAGCGATTTAAT
>18.4|7120648|39|NZ_CP046703|CRISPRCasFinder
AAACAAAGCATTATCAACAATTTCACCATCAATTGTCAC
>18.5|7120720|38|NZ_CP046703|CRISPRCasFinder
AAACCTAGCAGATTCATCAGATGGCAGACTGTAAACTA
>18.6|7120583|32|NZ_CP046703|CRT
GCATTATGGTTGCTGGTTTGTAGCGATTTAAT
>18.7|7120654|33|NZ_CP046703|CRT
AGCATTATCAACAATTTCACCATCAATTGTCAC
>18.8|7120726|32|NZ_CP046703|CRT
AGCAGATTCATCAGATGGCAGACTGTAAACTA

CRISPR arrays and Neighbor proteins around NZ_CP046703_18

CRISPR arrays

The CRISPR arrays of NZ_CP046703_18

>merge|NZ_CP046703|18|7120544-7120796|PILER-CR,CRISPRCasFinder,CRT
ATTGCAATTATCTTAAATCCCTATTAGGGATTGAAACAAGCATTATGGTTGCTGGTTTGTAGCGATTTAATATTGCAATTATCTTAAATCCCTATTAGGGATTGAAACAAAGCATTATCAACAATTTCACCATCAATTGTCACATTGCAATTATCTTAAATCCCTATTAGGGATTGAAACCTAGCAGATTCATCAGATGGCAGACTGTAAACTAATTGCAATTATCTTAAATCCCTATTAGGGATTGTGAAAA

>NZ_CP046703|18|6|7120544-7120723|PILER-CR
ATTGCAATTATCTTAAATCCCTATTAGGGATTGAAAC	AAGCATTATGGTTGCTGGTTTGTAGCGATTTAAT
ATTGCAATTATCTTAAATCCCTATTAGGGATTGAAAC	AAAGCATTATCAACAATTTCACCATCAATTGTCAC
ATTGCAATTATCTTAAATCCCTATTAGGGATTGAAAC

>NZ_CP046703|18|16|7120544-7120790|CRISPRCasFinder
ATTGCAATTATCTTAAATCCCTATTAGGGATTG	AAACAAGCATTATGGTTGCTGGTTTGTAGCGATTTAAT
ATTGCAATTATCTTAAATCCCTATTAGGGATTG	AAACAAAGCATTATCAACAATTTCACCATCAATTGTCAC
ATTGCAATTATCTTAAATCCCTATTAGGGATTG	AAACCTAGCAGATTCATCAGATGGCAGACTGTAAACTA
ATTGCAATTATCTTAAATCCCTATTAGGGATTG

>NZ_CP046703|18|7|7120544-7120796|CRT
ATTGCAATTATCTTAAATCCCTATTAGGGATTGAAACAA	GCATTATGGTTGCTGGTTTGTAGCGATTTAAT
ATTGCAATTATCTTAAATCCCTATTAGGGATTGAAACAA	AGCATTATCAACAATTTCACCATCAATTGTCAC
ATTGCAATTATCTTAAATCCCTATTAGGGATTGAAACCT	AGCAGATTCATCAGATGGCAGACTGTAAACTA
ATTGCAATTATCTTAAATCCCTATTAGGGATTGTGAAAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046703.1|WP_114080702.1|7107904_7108717_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|187616
NZ_CP046703.1|WP_114080691.1|7128752_7129058_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114080703.1|7106784_7107279_-|DUF2231-domain-containing-protein	unknown	unknown	gnl|CDD|226695
NZ_CP046703.1|WP_114080698.1|7117931_7119047_+|response-regulator	unknown	unknown	gnl|CDD|381147
NZ_CP046703.1|WP_114080692.1|7126252_7128481_+|adenylate/guanylate-cyclase-domain-containing-protein	unknown	unknown	gnl|CDD|226703
NZ_CP046703.1|WP_114080693.1|7125416_7126247_+|DUF928-domain-containing-protein	unknown	unknown	gnl|CDD|368720
NZ_CP046703.1|WP_114080700.1|7112252_7113893_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|226651
NZ_CP046703.1|WP_159402606.1|7133569_7133746_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114080701.1|7108896_7109835_+|cation-transporter	unknown	unknown	gnl|CDD|223131
NZ_CP046703.1|WP_114080699.1|7113929_7117229_-|response-regulator	unknown	unknown	gnl|CDD|274362
NZ_CP046703.1|WP_114080705.1|7105102_7106038_-|cytochrome-c-oxidase-subunit-II	unknown	unknown	gnl|CDD|224537
NZ_CP046703.1|WP_114080694.1|7123786_7125067_-|3-phosphoshikimate-1-carboxyvinyltransferase	unknown	unknown	gnl|CDD|235037
NZ_CP046703.1|WP_114080696.1|7120876_7122466_-|alkaline-phosphatase	unknown	unknown	gnl|CDD|226070
NZ_CP046703.1|WP_114080704.1|7106206_7106788_-|DUF2231-domain-containing-protein	unknown	unknown	gnl|CDD|226695
NZ_CP046703.1|WP_114080695.1|7122692_7123244_-|PEP-CTERM-sorting-domain-containing-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_012407782.1|7119381_7119561_+|high-light-inducible-protein	unknown	unknown	gnl|CDD|177653
NZ_CP046703.1|WP_114080690.1|7129700_7130057_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP046703.1|WP_114080689.1|7130155_7130503_-|cupin-domain-containing-protein	unknown	unknown	gnl|CDD|369571
NZ_CP046703.1|WP_114080688.1|7130499_7133394_-|pyruvate-phosphate-dikinase-PEP/pyruvate-binding-protein	unknown	unknown	gnl|CDD|235751
NZ_CP046703.1|WP_114080697.1|7119853_7120177_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP046703.1|WP_114080702.1|7107904_7108717_+|SDR-family-oxidoreductase	gnl|CDD|187616	cd05358, GlcDH_SDR_c, glucose 1 dehydrogenase (GlcDH), classical (c) SDRs. GlcDH, is a tetrameric member of the SDR family, it catalyzes the NAD(P)-dependent oxidation of beta-D-glucose to D-glucono-delta-lactone. GlcDH has a typical NAD-binding site glycine-rich pattern as well as the canonical active site tetrad (YXXXK motif plus upstream Ser and Asn). SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRS are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes have a 3-glycine N-terminal NAD(P)(H)-binding pattern (typically, TGxxxGxG in classical SDRs and TGxxGxxG in extended SDRs), while substrate binding is in the C-terminal region. A critical catalytic Tyr residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering), is often found in a conserved YXXXK pattern. In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) or additional Ser, contributing to the active site. Substrates for these enzymes include sugars, steroids, alcohols, and aromatic compounds. The standard reaction mechanism is a proton relay involving the conserved Tyr and Lys, as well as Asn (or Ser). Some SDR family members, including 17 beta-hydroxysteroid dehydrogenase contain an additional helix-turn-helix motif that is not generally found among SDRs.	2.89862e-146
NZ_CP046703.1|WP_114080703.1|7106784_7107279_-|DUF2231-domain-containing-protein	gnl|CDD|226695	COG4244, COG4244, Predicted membrane protein [Function unknown].	6.21838e-48
NZ_CP046703.1|WP_114080698.1|7117931_7119047_+|response-regulator	gnl|CDD|381147	cd19920, REC_PA4781-like, phosphoacceptor receiver (REC) domain of cyclic di-GMP phosphodiesterase PA4781 and similar domains. Pseudomonas aeruginosa cyclic di-GMP phosphodiesterase PA4781 contains an N-terminal REC domain and a C-terminal catalytic HD-GYP domain, characteristics of RpfG family response regulators. PA4781 is involved in cyclic di-3',5'-GMP (c-di-GMP) hydrolysis/degradation in a two-step reaction via the linear intermediate pGpG to produce GMP. Its unphosphorylated REC domain prevents accessibility of c-di-GMP to the active site. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	1.84544e-58
NZ_CP046703.1|WP_114080692.1|7126252_7128481_+|adenylate/guanylate-cyclase-domain-containing-protein	gnl|CDD|226703	COG4252, COG4252, Predicted transmembrane sensor domain [Signal transduction mechanisms].	5.72762e-152
NZ_CP046703.1|WP_114080700.1|7112252_7113893_+|alpha/beta-hydrolase	gnl|CDD|226651	COG4188, COG4188, Predicted dienelactone hydrolase [General function prediction only].	1.39318e-94
NZ_CP046703.1|WP_114080694.1|7123786_7125067_-|3-phosphoshikimate-1-carboxyvinyltransferase	gnl|CDD|235037	PRK02427, PRK02427, 3-phosphoshikimate 1-carboxyvinyltransferase; Provisional.	4.29711e-174
NZ_CP046703.1|WP_114080699.1|7113929_7117229_-|response-regulator	gnl|CDD|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	1.49728e-81
NZ_CP046703.1|WP_114080705.1|7105102_7106038_-|cytochrome-c-oxidase-subunit-II	gnl|CDD|224537	COG1622, CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 [Energy production and conversion].	3.31337e-53
NZ_CP046703.1|WP_114080701.1|7108896_7109835_+|cation-transporter	gnl|CDD|223131	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism].	1.5137e-47
NZ_CP046703.1|WP_114080696.1|7120876_7122466_-|alkaline-phosphatase	gnl|CDD|226070	COG3540, PhoD, Phosphodiesterase/alkaline phosphatase D [Inorganic ion transport and metabolism].	0
NZ_CP046703.1|WP_114080704.1|7106206_7106788_-|DUF2231-domain-containing-protein	gnl|CDD|226695	COG4244, COG4244, Predicted membrane protein [Function unknown].	1.93682e-33
NZ_CP046703.1|WP_012407782.1|7119381_7119561_+|high-light-inducible-protein	gnl|CDD|177653	PLN00014, PLN00014, light-harvesting-like protein 3; Provisional.	5.8566e-05
NZ_CP046703.1|WP_114080689.1|7130155_7130503_-|cupin-domain-containing-protein	gnl|CDD|369571	pfam07883, Cupin_2, Cupin domain. This family represents the conserved barrel domain of the 'cupin' superfamily ('cupa' is the Latin term for a small barrel).	1.0694e-12
NZ_CP046703.1|WP_114080688.1|7130499_7133394_-|pyruvate-phosphate-dikinase-PEP/pyruvate-binding-protein	gnl|CDD|235751	PRK06241, PRK06241, phosphoenolpyruvate synthase; Validated.	5.85929e-93
NZ_CP046703.1|WP_114080693.1|7125416_7126247_+|DUF928-domain-containing-protein	gnl|CDD|368720	pfam06051, DUF928, Domain of Unknown Function (DUF928). Family of uncharacterized bacterial protein.	3.99009e-91

Protein sequences

>NZ_CP046703.1|WP_114080697.1|7119853_7120177_+|hypothetical-protein
MEIPQRVSVRYKDASFNSNEIRLRTFRLGLQIWEEQTKPRKTELYQFISSCLKQVDRQDRFMFSLLFIELTDMIRNSSLERGTKEVLIKTAFREFACAITDFEDVGK
>NZ_CP046703.1|WP_012407782.1|7119381_7119561_+|high-light-inducible-protein
MTGFKNPAPIVSEDPNAVRFGFTPQSENWNGRLAMIGFLSAILIEAFSGQGLLHFWGIL
>NZ_CP046703.1|WP_114080698.1|7117931_7119047_+|response-regulator
MELSQSSKGDILIVDDTLDNLRLLSAMLTEQGYEVRSVTNGSMALIGIQAQPPDLILLDITMPGMNGYEVCQRLKSNPQTQEIPVIFISALNEVFDKVKAFSVGGVDFINKPFQIEEVVARMEHQLNLCRLQMQLQEQNRRLQETEAELRRSLEHQKALNQRIEEMVALEERNRIARDIHDSLGHSLVALNVQMETALTLWETDPNRARSFLLAAKKLGSEALQEVRESVSAIRSDPLHGQLLENAIANLAEEFYHLTDVLPYCKIDLSQPLSDSVNHVVYRIIQEGLTNIYKHANATAVQIRIQTTAAGLSLILQDNGKGFECDQSVAGYGLQGMRERIATVNAQLEIVSKTGAGCRIVANFARDEGGGG
>NZ_CP046703.1|WP_114080699.1|7113929_7117229_-|response-regulator
MPSFTLRLSKLTKNVQLRHILVVPFVLQISLAVGLTGWLSIHNGQRAVNEVAIQLRNEITARIQQYLKVYVETPHKINQLNANAIKLGELNIQKLLTLEQHLWYQLKTFDTVTAVYFGSEYGEHVAVQRADDGQFEVKLSGKSTGNEIRIYAADQPGHYTKLLRSKPNYDPRTRPWYQSAVKSKTASWGGIYKLFATPKYVLNASLPIYDNGGNLLGVTAVDFSLTGISQYLRSLKIGRTGETFILERQTGLLVGSSATQQPYVIANPTAPIIDQNPVRVQAIASNDILTRRTAEYLQQHFVDLTQITEKQQLDFDIEGQRQFLQIVPMQNQQGLDWLIVVVVPERDFMDQINANTRSTIVLCLCAFALATGLGILTAGWITQPILRLGSTAKAIAAGNLDQKVSVNSTTELNSLAESFNLMAHQLRESFLALARTNEELESRVTQRTRELGEKNAQLQREIRVSEAAQRDRRKVEAALKTSEAELRLMFAAMTDMVVVFDAEGRYQKYVQTKYVLTQSFAYKPDMDRIGKKVDEVLPKEIANLILDAIQQALHLREEPRNPDGSRKNVFVEYHLANKNRETWFLASVSPLSDNTVLWVARDITKQKKTEAALKQAKETADAANLAKSQFLSNMSHELRTPLNIILGFTQLLLRNRSLNSQQQEYLDTINRSGEDLLTLINDVLEMSKIEAGRVILNETNFDLYGLLDRLQQMFALKAQSRGLKLILERSPTIPQYICADESKLRQVLVNLLGNAIKFTRIGQVTLRVETPNQNITPDEPITLNFSVEDTGCGIADSDFNRLFEPFVQTEAGQKAQEGTGLGLPISQRFVRLMGGDIRVNSTLGKGSIFTFDIRTRAVIMDTLPTPAPSRQVIGLEKGQPSYRILIVEDKLENRQLLVELLTPVGFEVREAVNGQAAIELWQNWSPHLIWMDLRMPIMNGFEATKQIKAAGAQTPVIIALTGSAFEEDRLTALSVGFDDFVRKPFRTTVIFEKMAEYLGVRYVYADERENQEKASWPSNASFITPKLTVADLSVMPSDWIEQLHQAALRINAKEILMLIKQIPEQHAHLIVALTNLVDCFCFEEIIALGTTKKINNPKM
>NZ_CP046703.1|WP_114080700.1|7112252_7113893_+|alpha/beta-hydrolase
MTHHLMGKQTVWQKLALRIFSMALLPTLTTYPAFGAERLKFNYGVLERSIPISSLENYAKTGNVDDDFAGYSKYVDKKQLTQLRKVLLTRIPLNEVEISQFLYTPIGERLLQRLGKIIQTESRLSGFYAIRSALILSAADQKDFTLLNILQKFPASSISINLNQTLEIAETLQDLVNQTQNAVALINEESQHNVITVSKLDSIPLMDLGKTGNFRFLKQTITLNDLTRNRRFLADIYLPVAPNTRKIIVISHGLGSDRTSFAYLAEHLASYGFVVAVPEHPGSDSKQLQALLKGTTNQVTNPRELIDRPLDIKYLLDELTRLSKSNPTFQGRLNLDQVGIIGQSFGGYTALALAGAKINFEQLRADCSALEDTLNVSLLLQCLGVNLPNFQYNLSDTRIKAAIVINPVGSSIFGQASLSQIKIPVMIISSSYDTVAPALLEQIQPFTWLTTSNKYLTLINGGTHFSTIAESPNATIPIPIQAVGSSPALARRYVKALSVPFFETYIAGQPNYLPYLSTEYVNKISQQPLPLSLITSLTSEELKTYK
>NZ_CP046703.1|WP_114080701.1|7108896_7109835_+|cation-transporter
MATDSSKKTIFAAIGSNLAIAITKFIAASITGSSAMISEGIHSVVDTGDQLVLLLGLHRSQKPADDSHPFGYGQELYFWTFIVAILIFAIGGGMSIYEGITHLINPSPLEDPIWNYIVLSMAIILEGFSWTVALKEFLPTKGKQNFWQAIKNSKDPTVFTILFEDTAAILGLIVALIGIFLGHLFNNVYFDGIASIIIGIILSIVAVLLARESKGLLVGESANPQTIANIRSLSKTEPGVQEFIRVLTMQLAPQEVLLNLEIQFSKNLTGEEIALTVERLEIKIRRKHPEIKQIFIEAKSLAATRKYSQPFN
>NZ_CP046703.1|WP_114080702.1|7107904_7108717_+|SDR-family-oxidoreductase
MSYFPYLLKGQKALVTGASSGIGEAIARNLATSGAAVAINYHSEAESAHKIVDDIKANNGEAFAIQADVSKEDQVKAMFSKTLQEFGTIDILVSNAGIQKDSAFIDMTIEQWNAVIGINLTGQFLCAREAAKEFLRRGVKPNISCAAGKIICMSSVHEVIPWAGHVNYATSKGGINMMMKSIAQELAPHKIRVNSIAPGAIKTPINKSAWDTPEAEAKLLKLIPAKRVGNVEDIAKAAVWLASDDSDYVNGTTLFVDGGMTLYPGFTENG
>NZ_CP046703.1|WP_114080703.1|7106784_7107279_-|DUF2231-domain-containing-protein
MPALSLNSQNLPYPDPLHPIIVHFVIAMVLFSFVCDVLGYFTRNVRLFEVSFWNMFVAAIAIFIAIIFGQFEAGLAQAEKAAQSTLNYHTVLGWSLGAMVAAIAAWRFVIRNRSPRKVPPAYLGAATFLVCLVFLQVYLGSKLFWVYGLHVEPVVQAMKQGVSP
>NZ_CP046703.1|WP_114080704.1|7106206_7106788_-|DUF2231-domain-containing-protein
MNPQLIEQLRLRLGANGLPYEIPIHPQLVHLTLGLFIIAIIFDIAGVLFSLEKPIFKFLGLAAIRSSFFDVGWYNLIAAAGITFFTVAAGFFELLLANPPVDQKSAWGLNAGWTMLLHGLGGVLLLGIIVAMTVWRGLQRYRWRKDASRQVQWSYLLAGIAILGILFVHGTLGAQLGEEFGIHVTAAKLGRHN
>NZ_CP046703.1|WP_114080705.1|7105102_7106038_-|cytochrome-c-oxidase-subunit-II
MFSVFEYILIAVYVAVLLVVSRWIGQQAFSWMPPQATAEAQRVDDLFSFLVSIGAFILLGLVGVMLYAIAFHRAPPEDYTEGHPSRGDTRLEILWTATPTLLVVWIAFQSFNIYQQLNILGLKQIVHLHTPLESASAATISVGAARRRHRPKPASETIDVFVKQWDWSFRYPNNVTSNQLHLPINRSTRLNLQAQDVIHGFYVPEFRLKQDIIPGRDIDLVLTPIRAGKYRLKDSQFSGTYFALMETDVYVESLNQYNQWLTQTASSEQTPVNQAVAENIQPPKTLFNSGWYTVTPAQPGIANKRKQNNDT
>NZ_CP046703.1|WP_114080696.1|7120876_7122466_-|alkaline-phosphatase
MVDYRNFEQFLHSRMKRRNLIIGAGALSGLAIANQFSHQTAIAKSRFSNYPFTLGVASGEPYPTSVVIWTRLAPEPLEGGGMPPVNVPIRWEVATDPDMRRIVSRGTVLATPQLAHSVRVVVEGLQSDTWYWYRFLVGQDASPIGRTRTAPLANSYLSKFNFGLVSCQNYQQGFYTAYKYLAQDDLDLVVHVGDYIYEGGISTTSPRQHNSTEILTLEDYRNRHALYKTDSNLQAAHAAFPWIVTWDDHEVENNYANNISEIDTEPDQDRAIFLQRRAVAYQAYYEHMPLRPLSRPVGPDMQLYRRLSFGNLATFHVLDTRQYRTDQPCGDGTKERCPENLDPNATITGKAQEQWLFDGLNSSQSKWNVLAQQVPIAQRDMKPGEGGTYSMDKWDGYVASRDRLMAFLGQRQPSNPVSLAGDVHSHWAMNLKANFDNPQSATVGSEFVCSSISSGGDGSDSTPAVEAYLPDNPHIKFFNNQRGYVRCSLTPTNWQTDYLVMSNVTTPFGTLSKRASFVVEDGRPEIQQV
>NZ_CP046703.1|WP_114080695.1|7122692_7123244_-|PEP-CTERM-sorting-domain-containing-protein
MKIVPKLAIAAASLTLGFAVVDAKSVSAAIINYAFTVDSPITKGNGFFSFDDSTLSNDYTPEATIKSLSFQFDGDSTIYTEQDDTNYPDFPVAFQTTSLTGQTSFALDYLFNDKSNPASSISYEIIGEDFTIFSRTSPDAEPISGKVSYTQVPEPTPLFGALFACSFGLMMKRKVTLMKKVKI
>NZ_CP046703.1|WP_114080694.1|7123786_7125067_-|3-phosphoshikimate-1-carboxyvinyltransferase
MDTIAIPALNRPVDATVEIPGSKSLTNRALLVAALAQGDSILENALFSEDSEYFVKCVEQLGIPITLNPNLAQIQVAGRGGDIPAKQADLFVGLAGTAARFISALVALGNGEYRLDGVPRMRERPMGDMLTVLQTGGATVNFEGNSGFMPYTVYSQGFAGGNFRLKANQTSQQLSALLMIAPYAQQDTTIEVEGTLVSQSYVKMTCRLMADFGVEVNQIGDNQFQIKAGQRYQAQHYTVEPDASNASYFFAAAAVTGGRVRVKHLTKQSCQGDILWLDVLEQMGCEVKDSDDYTEVTGPKQLQGIDIDMNDISDLVQTLAAIAPFASSPITIRNVEHIRYKETDRIKAVVTELRRLGVQVEEFPDRLKIEPGPITPAEIETYHDHRMAMAFAVTGLKVPGIVIKDPGCTAKTFPDYFTRFFKMLEE
>NZ_CP046703.1|WP_114080693.1|7125416_7126247_+|DUF928-domain-containing-protein
MKRIKPFLYFLTFSLPLGLLSALTAQVHAQSYHPNKTWQISQAFKPPQRGKPPASAGGSTRGGSCLIGKKLITPLMPPDKLGLTFAQHPTFFWYVPPFKVKTAKFVLLAEDQDVFYETSFTLPDKPGIISFKLPESSPGLAVGKTYHWYLTIVCNAQDSSDNPTVEGWVERTQPGSSLSEALVKANVYKLPTIYAEAGIWHEALTSLVQLRRTEPNNFKARLDWRQFFKSVGLSAIASEPLIDCCTSKKEGHGAKVEFPTPNSPLSTPHSLFPTQH
>NZ_CP046703.1|WP_114080692.1|7126252_7128481_+|adenylate/guanylate-cyclase-domain-containing-protein
MWAKLKSQIWQWRGVLLAVPNITALVIALRLTGLLQLLELAALDQFFLLRPQESPDTRIVIVEINEADIRKQGQWPMSDGKLASLLEKIKQQQPRAIGLDIYRDLPVNPGHEALLKVFKSTPNLIGVQKVSDTVDSSAVDSSPELKRLDQIGSNDLPIDGDGKIRRSLLYVNLNNDQILESFGLKLALLYLKPEGITAKPSATNSNYLQLNRGVFPIFEANDGGYVRADAGSYQVLLNYRGRIQQFTKVSLGEVQDKPIPPDLMRDKVVLIGATAESLKDLFYTPYSSNVLTDPERMAGITIHANLISQILSAAMDGRPLIKCLPEPLEWLSILIWSIIGASLCWLQRHSSNQKTLMAVSVLLAGGGLIGGSFLAFLAGWWIPVVPSLLAFAGSAIALTQYIAQSATEMRKTLGRYLTDEIVSNILETPSGLKLGGERRKVTVLVSDLRGFSAISEQLPPEEVVKILNLYLGTMTDVINQYKGTINEFMGDGIFVIFGAPISRIDDSQRAIACAIAMQLAMQQVNEQNRQMNFPILEMGIGMNTGEAVAGNVGSQKRAQYTVIGSHVNLAARIESYTVGGQILISENTCKDANIDLQIAGQLQIEPKGMRHPVTICEIRGIGGKYNLFLPDDDEEIIVLNQEVPVKYTILQGKYAVGKVFLGALISLSEKGAQLRSLDSLEILSNLKLKLLIEAEMATEEEHIYAKVIQQSNVDKHLFLLRFTAVPPKAMAMLNALRQPESG
>NZ_CP046703.1|WP_114080691.1|7128752_7129058_+|hypothetical-protein
MTNINNFQRLVELANEYGIICQPTPEECLIASLPGDEDFLLAFTWSGAVEGEPPEHELIAISVQDIVKEVTVAAWQIPIYLFGNVLRQAQMLVAAHKDFFS
>NZ_CP046703.1|WP_114080690.1|7129700_7130057_+|hypothetical-protein
MNKFLLSLLSSPVLISSILSMGVMLNQAQAIEPQSETQTTDRLSCIRNKHKVGLVCARASVLAQIPNYQREIEFSKEDAPMLEFNDEESNVAIDLFGCDCPACINSLRQMRGATPLVY
>NZ_CP046703.1|WP_114080689.1|7130155_7130503_-|cupin-domain-containing-protein
MITNSLKDLPEESVSHNPEIKKKVMLRFGDLPHLTNFSQARFAPGQTAPAHAHQDMCEVFFVEAGSGVIHIDGTEYPLLPGNCVAIEVGEVHEVVNSGSTELVLTYFGLRVEKSA
>NZ_CP046703.1|WP_114080688.1|7130499_7133394_-|pyruvate-phosphate-dikinase-PEP/pyruvate-binding-protein
MFEPWGVLVILIICPLLGGLPLIAWIAYSLTGKQLSQVGTRNISVSAAFYHGGKFVGILAVLSEAFKGIAAVFLTRLFFPEGSFWELIALIALVIGRYWIGRGAGTTNVVWGFVVHDPLVAMFVSFFAGISFTVLQSKQAVKFGVLLLFPLFVAILHLSDIPRMLAAVALAGLMAWIYAKIPDDMNLPVQEAQTESQAMLEFLRGDRAMVSLDEELDAAIVGEKAATLSQIKRWGYPVPKGWVLAPIDDPKVLTEFLQPSELSPLVVRSSAIGEDSEQASAAGQYETVLNVTSPEALQQAIAQVQASYNHPSAVQYRRDRGSSDTAMAVLIQQQVQSVYSGVAFSRDPITQQGDAIIIEALPGSPTQIVSGKVTPEQYRAFVVETEKSSSVQLEGEGRVPQALIKQVAYLAYRLEKRYHGTPQDIEWSYDGQTLWVLQSRPITTLLPIWTRKIAAEVIPGVIHPLTWSINRPLTCGVWGDFFTLVLGDRALGLDFNETATLHYSRAYFNASLLGNIFLRMGLPPESLEFLTRGAKLSKPSLQSTWENLPGLGRLLKRELNLEKDFKQDYHQRFIPGLSQLAQENVDNLEPAKLLIRIDFILELLRHGTYYSILAPLSAALRQAIFRVKDGQIDNSVTPEVAALRSLSAIATDAKQVLLEFEPQQVFEQLKQTPEGEKILQEFDELLQDYGYLSEVGTDISVPTWRENPQMIKQMFVQLMQGNEPQAGAKDAINSIFAGKRKRSFVQRRVDIKGRVTEVYSRLLAELRWSFVALEKIWLKSGLLQKTGDIFFLNFDEVRRLVEGDDSRLIEELDKLVESRRSQFVQDSEFIQIPLLVYGNTPPHPLAPSALYSDQILQGIGASHGQAEGRVKVLRNLQDVPEIDRDTILVVPYTDSGWAPLLLRAGGLIAEVGGRLSHGAIVAREYGIPAVMDVRGATWLLQDGQRVRIDGSRGIVELSNDLRPE
>NZ_CP046703.1|WP_159402606.1|7133569_7133746_-|hypothetical-protein
MFHAPTREDYKAMSDLNRGIMKFEGADSPKVVTISTVLLLGSIAALIIWALQAAYALN

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP046703_14	14.6|5454672|30|NZ_CP046703|CRT	5454672-5454701	30	NZ_CP046703.1	5262577-5262606	2	0.933

1. spacer 14.6|5454672|30|NZ_CP046703|CRT matches to position: 5262577-5262606, mismatch: 2, identity: 0.933

gaactccacgcctcccgctacgccgaacgc	CRISPR spacer
gaacgccacgcctcccgccacgccgaacgc	Protospacer
**** *************.***********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP046703_10	10.2|5414846|35|NZ_CP046703|CRISPRCasFinder	5414846-5414880	35	NZ_CP026690	Nostoc sp. 'Peltigera membranacea cyanobiont' N6 plasmid pNPM8, complete sequence	35852-35886	5	0.857
NZ_CP046703_10	10.2|5414846|35|NZ_CP046703|CRISPRCasFinder	5414846-5414880	35	AP018319	Nostoc sp. HK-01 plasmid plasmid1 DNA, complete genome	388211-388245	6	0.829
NZ_CP046703_9	9.3|4930934|31|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT	4930934-4930964	31	AP014273	Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S26-C46, *** SEQUENCING IN PROGRESS ***	33652-33682	7	0.774
NZ_CP046703_10	10.2|5414846|35|NZ_CP046703|CRISPRCasFinder	5414846-5414880	35	AP018319	Nostoc sp. HK-01 plasmid plasmid1 DNA, complete genome	323177-323211	7	0.8
NZ_CP046703_14	14.3|5454492|30|NZ_CP046703|CRT	5454492-5454521	30	NC_012811	Methylorubrum extorquens AM1 megaplasmid, complete sequence	63230-63259	7	0.767
NZ_CP046703_14	14.6|5454672|30|NZ_CP046703|CRT	5454672-5454701	30	NZ_CP027239	Dietzia sp. oral taxon 368 strain W5195 plasmid unnamed1, complete sequence	16170-16199	7	0.767
NZ_CP046703_14	14.6|5454672|30|NZ_CP046703|CRT	5454672-5454701	30	NC_016587	Azospirillum lipoferum 4B plasmid AZO_p4, complete sequence	639730-639759	7	0.767
NZ_CP046703_14	14.6|5454672|30|NZ_CP046703|CRT	5454672-5454701	30	NC_013858	Azospirillum sp. B510 plasmid pAB510d, complete sequence	101317-101346	7	0.767
NZ_CP046703_14	14.6|5454672|30|NZ_CP046703|CRT	5454672-5454701	30	NZ_CP054617	Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence	34067-34096	7	0.767
NZ_CP046703_6	6.7|2343287|34|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT	2343287-2343320	34	NZ_CP014203	Clostridium baratii strain CDC51267 plasmid pNPD11_1, complete sequence	81712-81745	8	0.765
NZ_CP046703_18	18.7|7120654|33|NZ_CP046703|CRT	7120654-7120686	33	MT119360	Enterococcus phage nattely, complete genome	83047-83079	8	0.758
NZ_CP046703_18	18.7|7120654|33|NZ_CP046703|CRT	7120654-7120686	33	MT119361	Enterococus phage vipetofem, complete genome	2069-2101	8	0.758
NZ_CP046703_6	6.7|2343287|34|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT	2343287-2343320	34	MH595538	Vibrio phage BONAISHI, complete genome	260291-260324	9	0.735
NZ_CP046703_14	14.6|5454672|30|NZ_CP046703|CRT	5454672-5454701	30	NZ_CP023065	Sinorhizobium sp. CCBAU 05631 plasmid pSS05631a, complete sequence	346964-346993	9	0.7
NZ_CP046703_14	14.6|5454672|30|NZ_CP046703|CRT	5454672-5454701	30	NC_000914	Sinorhizobium fredii NGR234 plasmid pNGR234a, complete sequence	77203-77232	9	0.7
NZ_CP046703_14	14.6|5454672|30|NZ_CP046703|CRT	5454672-5454701	30	NZ_CP023072	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666a, complete sequence	472020-472049	9	0.7
NZ_CP046703_17	17.2|6707991|35|NZ_CP046703|CRISPRCasFinder,CRT	6707991-6708025	35	LN885237	Lactobacillus phage EV3 genome assembly, complete genome: monopartite	25227-25261	9	0.743
NZ_CP046703_17	17.20|6707992|35|NZ_CP046703|PILER-CR	6707992-6708026	35	LN885237	Lactobacillus phage EV3 genome assembly, complete genome: monopartite	25227-25261	9	0.743
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	MT119360	Enterococcus phage nattely, complete genome	83045-83079	9	0.743
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	MT119361	Enterococus phage vipetofem, complete genome	2069-2103	9	0.743
NZ_CP046703_6	6.1|2342848|34|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT	2342848-2342881	34	EU545650	Acidianus filamentous virus 9, complete genome	5283-5316	10	0.706
NZ_CP046703_6	6.7|2343287|34|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT	2343287-2343320	34	MN694558	Marine virus AFVG_250M9, complete genome	1508-1541	10	0.706
NZ_CP046703_6	6.7|2343287|34|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT	2343287-2343320	34	MN694640	Marine virus AFVG_250M10, complete genome	1509-1542	10	0.706
NZ_CP046703_9	9.6|4931148|35|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT	4931148-4931182	35	NZ_CP040345	Bacillus albus strain DLOU-Yingkou plasmid unnamed1, complete sequence	5688-5722	10	0.714
NZ_CP046703_10	10.2|5414846|35|NZ_CP046703|CRISPRCasFinder	5414846-5414880	35	NZ_CP018436	Klebsiella pneumoniae strain MNCRE53 plasmid pMNCRE53_3, complete sequence	20043-20077	10	0.714
NZ_CP046703_10	10.2|5414846|35|NZ_CP046703|CRISPRCasFinder	5414846-5414880	35	NZ_CP018426	Klebsiella pneumoniae strain MNCRE69 plasmid pMNCRE69_3, complete sequence	20043-20077	10	0.714
NZ_CP046703_10	10.2|5414846|35|NZ_CP046703|CRISPRCasFinder	5414846-5414880	35	NZ_CP036448	Klebsiella pneumoniae strain KPNIH45 plasmid pKPC-e4b7, complete sequence	6622-6656	10	0.714
NZ_CP046703_10	10.2|5414846|35|NZ_CP046703|CRISPRCasFinder	5414846-5414880	35	NZ_CP045693	Klebsiella pneumoniae strain TK421 plasmid pTK421_3, complete sequence	23668-23702	10	0.714
NZ_CP046703_10	10.2|5414846|35|NZ_CP046703|CRISPRCasFinder	5414846-5414880	35	NZ_CP018432	Klebsiella pneumoniae strain MNCRE78 plasmid pMNCRE78_3, complete sequence	20042-20076	10	0.714
NZ_CP046703_10	10.2|5414846|35|NZ_CP046703|CRISPRCasFinder	5414846-5414880	35	NZ_CP028954	Klebsiella pneumoniae strain AR_0141 plasmid unnamed1, complete sequence	163822-163856	10	0.714
NZ_CP046703_10	10.2|5414846|35|NZ_CP046703|CRISPRCasFinder	5414846-5414880	35	NZ_CP014069	Citrobacter amalonaticus strain FDAARGOS_165 plasmid unnamed	6497-6531	10	0.714
NZ_CP046703_10	10.2|5414846|35|NZ_CP046703|CRISPRCasFinder	5414846-5414880	35	NZ_CP022274	Citrobacter freundii strain 18-1 plasmid pA18-1, complete sequence	5110-5144	10	0.714
NZ_CP046703_10	10.2|5414846|35|NZ_CP046703|CRISPRCasFinder	5414846-5414880	35	NZ_CP026384	Serratia sp. SSNIH1 plasmid pSER-840e, complete sequence	3580-3614	10	0.714
NZ_CP046703_10	10.2|5414846|35|NZ_CP046703|CRISPRCasFinder	5414846-5414880	35	CP052538	Klebsiella pneumoniae strain B16KP0141 plasmid pB16KP0141-1, complete sequence	77250-77284	10	0.714
NZ_CP046703_10	10.2|5414846|35|NZ_CP046703|CRISPRCasFinder	5414846-5414880	35	NZ_CP029724	Klebsiella pneumoniae strain AR_0140 plasmid unnamed2, complete sequence	101789-101823	10	0.714
NZ_CP046703_10	10.2|5414846|35|NZ_CP046703|CRISPRCasFinder	5414846-5414880	35	NZ_CP036437	Citrobacter sp. ABFQG plasmid pKPC-e4b7, complete sequence	38193-38227	10	0.714
NZ_CP046703_10	10.2|5414846|35|NZ_CP046703|CRISPRCasFinder	5414846-5414880	35	NZ_CP036440	Klebsiella pneumoniae strain ABFQB plasmid pKPC-e4b7, complete sequence	44387-44421	10	0.714
NZ_CP046703_10	10.2|5414846|35|NZ_CP046703|CRISPRCasFinder	5414846-5414880	35	NZ_CP027143	Enterobacter hormaechei subsp. hoffmannii strain AR_0365 plasmid unnamed3	30065-30099	10	0.714
NZ_CP046703_10	10.2|5414846|35|NZ_CP046703|CRISPRCasFinder	5414846-5414880	35	NZ_CP043513	Enterobacter kobei strain EB_P8_L5_01.19 plasmid unnamed2, complete sequence	21278-21312	10	0.714
NZ_CP046703_10	10.2|5414846|35|NZ_CP046703|CRISPRCasFinder	5414846-5414880	35	NZ_CP026716	Klebsiella oxytoca strain AR_0028 plasmid unitig_1_pilon, complete sequence	14072-14106	10	0.714
NZ_CP046703_10	10.2|5414846|35|NZ_CP046703|CRISPRCasFinder	5414846-5414880	35	NZ_CP016810	Klebsiella pneumoniae strain DHQP1002001 plasmid p_IncFIB_DHQP1002001, complete sequence	23038-23072	10	0.714
NZ_CP046703_10	10.2|5414846|35|NZ_CP046703|CRISPRCasFinder	5414846-5414880	35	NZ_CP032893	Enterobacter kobei strain WCHEK045523 plasmid p1_045523, complete sequence	90607-90641	10	0.714
NZ_CP046703_11	11.1|5414955|34|NZ_CP046703|CRT	5414955-5414988	34	MN694720	Marine virus AFVG_250M584, complete genome	44001-44034	10	0.706
NZ_CP046703_11	11.1|5414955|34|NZ_CP046703|CRT	5414955-5414988	34	NZ_CP021787	Acinetobacter baumannii strain A85 plasmid pA85-3, complete sequence	43983-44016	10	0.706
NZ_CP046703_11	11.1|5414955|34|NZ_CP046703|CRT	5414955-5414988	34	NZ_CP023028	Acinetobacter baumannii strain 10042 plasmid pAba10042b, complete sequence	90970-91003	10	0.706
NZ_CP046703_11	11.1|5414955|34|NZ_CP046703|CRT	5414955-5414988	34	NZ_CP039024	Acinetobacter baumannii ATCC 17978 substr. PMR-High plasmid unnamed1	17827-17860	10	0.706
NZ_CP046703_11	11.1|5414955|34|NZ_CP046703|CRT	5414955-5414988	34	NZ_CP039519	Acinetobacter baumannii strain TG22653 plasmid pTG22653, complete sequence	115713-115746	10	0.706
NZ_CP046703_11	11.1|5414955|34|NZ_CP046703|CRT	5414955-5414988	34	NC_025109	Acinetobacter baumannii strain A85 plasmid pA85-3 clone GC1 AbaR4 resistance island, complete sequence	43984-44017	10	0.706
NZ_CP046703_11	11.1|5414955|34|NZ_CP046703|CRT	5414955-5414988	34	NZ_CP015485	Acinetobacter baumannii strain ORAB01 plasmid pORAB01-2, complete sequence	22131-22164	10	0.706
NZ_CP046703_11	11.1|5414955|34|NZ_CP046703|CRT	5414955-5414988	34	NZ_CP050404	Acinetobacter baumannii strain VB2486 plasmid pVB2486_1, complete sequence	57223-57256	10	0.706
NZ_CP046703_11	11.1|5414955|34|NZ_CP046703|CRT	5414955-5414988	34	CP040043	Acinetobacter baumannii strain VB958 plasmid unnamed3, complete sequence	44248-44281	10	0.706
NZ_CP046703_11	11.1|5414955|34|NZ_CP046703|CRT	5414955-5414988	34	NZ_CP015865	Vibrio campbellii CAIM 519 = NBRC 15631 strain ATCC 25920, CAIM 519T plasmid unnamed, complete sequence	71996-72029	10	0.706
NZ_CP046703_11	11.1|5414955|34|NZ_CP046703|CRT	5414955-5414988	34	LT605060	Acinetobacter calcoaceticus strain NCTC7364 genome assembly, plasmid: 2	132719-132752	10	0.706
NZ_CP046703_11	11.1|5414955|34|NZ_CP046703|CRT	5414955-5414988	34	NZ_CP020594	Acinetobacter baumannii strain USA15 plasmid pUSA15_1, complete sequence	88403-88436	10	0.706
NZ_CP046703_11	11.1|5414955|34|NZ_CP046703|CRT	5414955-5414988	34	NZ_MG954377	Acinetobacter baumannii strain SGH9601 plasmid pS21-2, complete sequence	109812-109845	10	0.706
NZ_CP046703_11	11.1|5414955|34|NZ_CP046703|CRT	5414955-5414988	34	NZ_CP012008	Acinetobacter baumannii strain Ab04-mff plasmid pAB04-2, complete sequence	51527-51560	10	0.706
NZ_CP046703_11	11.1|5414955|34|NZ_CP046703|CRT	5414955-5414988	34	NZ_CP012005	Acinetobacter baumannii strain ATCC 17978-mff plasmid pAB3, complete sequence	113694-113727	10	0.706
NZ_CP046703_11	11.1|5414955|34|NZ_CP046703|CRT	5414955-5414988	34	NZ_MK941846	Proteus mirabilis strain PM1157 plasmid pOXA-23, complete sequence	30780-30813	10	0.706
NZ_CP046703_11	11.4|5414955|35|NZ_CP046703|PILER-CR	5414955-5414989	35	MN694720	Marine virus AFVG_250M584, complete genome	44000-44034	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP021787	Acinetobacter baumannii strain A85 plasmid pA85-3, complete sequence	76886-76920	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_MG954379	Acinetobacter baumannii strain SGH0905 plasmid pS32-2, complete sequence	61384-61418	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP020577	Acinetobacter baumannii strain SSA12 plasmid pSSA12_1, complete sequence	68988-69022	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP023028	Acinetobacter baumannii strain 10042 plasmid pAba10042b, complete sequence	79537-79571	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	MK531538	Acinetobacter baumannii strain MC23 plasmid pMC23.1, complete sequence	57992-58026	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP027243	Acinetobacter baumannii strain WCHAB005078 plasmid p1_005078, complete sequence	59646-59680	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_KY022424	Acinetobacter baumannii strain Ab8098 plasmid pAb8098, complete sequence	18832-18866	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP035052	Acinetobacter baumannii strain ABUH763 plasmid p74.1Kbp, complete sequence	64640-64674	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP017657	Acinetobacter baumannii strain KAB08 plasmid unnamed, complete sequence	24363-24397	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP012008	Acinetobacter baumannii strain Ab04-mff plasmid pAB04-2, complete sequence	18617-18651	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NC_025111	Acinetobacter baumannii strain D72 plasmid pD72-2, complete sequence	60651-60685	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	CP033518	Acinetobacter baumannii strain 2008S11-069 plasmid p2008S11-069-2, complete sequence	44230-44264	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_KF889012	Acinetobacter baumannii TYTH-1 plasmid pAB_CC, complete sequence	47325-47359	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP032742	Acinetobacter baumannii strain C25 plasmid unnamed2	6779-6813	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NC_025109	Acinetobacter baumannii strain A85 plasmid pA85-3 clone GC1 AbaR4 resistance island, complete sequence	76887-76921	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP016302	Acinetobacter baumannii strain CMC-CR-MDR-Ab66 plasmid pCMCVTAb2-Ab66, complete sequence	30371-30405	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP016297	Acinetobacter baumannii strain CMC-CR-MDR-Ab4 plasmid pCMCVTAb2-Ab4, complete sequence	31266-31300	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP033857	Acinetobacter sp. FDAARGOS_493 plasmid unnamed1, complete sequence	58428-58462	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NC_017163	Acinetobacter baumannii 1656-2 plasmid ABKp1, complete sequence	38131-38165	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP050392	Acinetobacter baumannii strain VB11737 plasmid pVB11737_1, complete sequence	60649-60683	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP050413	Acinetobacter baumannii strain PM192696 plasmid pPM192696_1, complete sequence	60647-60681	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP017649	Acinetobacter baumannii strain KAB04 plasmid unnamed, complete sequence	26496-26530	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP050404	Acinetobacter baumannii strain VB2486 plasmid pVB2486_1, complete sequence	89639-89673	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_LT984690	Acinetobacter baumannii isolate K50 plasmid I, complete sequence	70147-70181	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP029571	Acinetobacter baumannii strain DA33098 plasmid pDA33098-71, complete sequence	62216-62250	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP039994	Acinetobacter baumannii strain TG22182 plasmid pTG22182_1, complete sequence	60082-60116	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP008851	Acinetobacter baumannii strain AC29 plasmid pAC29b, complete sequence	36283-36317	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP014216	Acinetobacter baumannii strain YU-R612 plasmid unnamed1, complete sequence	44567-44601	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP017655	Acinetobacter baumannii strain KAB07 plasmid pKAB07, complete sequence	16873-16907	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP023030	Acinetobacter baumannii strain 9102 plasmid pAba9102a, complete sequence	2480-2514	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP023030	Acinetobacter baumannii strain 9102 plasmid pAba9102a, complete sequence	81088-81122	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	CP040043	Acinetobacter baumannii strain VB958 plasmid unnamed3, complete sequence	72125-72159	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP050915	Acinetobacter baumannii strain DT-Ab007 plasmid unnamed1, complete sequence	82572-82606	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP050909	Acinetobacter baumannii strain DT-Ab022 plasmid unnamed2, complete sequence	61743-61777	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP008707	Acinetobacter baumannii strain AB5075-UW plasmid p1AB5075, complete sequence	74159-74193	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP017643	Acinetobacter baumannii strain KAB01 plasmid unnamed, complete sequence	9002-9036	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP023033	Acinetobacter baumannii strain 7847 plasmid pAba7847b, complete sequence	59981-60015	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	CP014292	Acinetobacter baumannii strain AB34299 plasmid unnamed1, complete sequence	17871-17905	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP027121	Acinetobacter baumannii strain AR_0056 plasmid unnamed2, complete sequence	31452-31486	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP030109	Acinetobacter baumannii strain DA33382 plasmid pDA33382-85, complete sequence	34509-34543	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP017651	Acinetobacter baumannii strain KAB05 plasmid unnamed, complete sequence	35666-35700	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP020580	Acinetobacter baumannii strain SSMA17 plasmid pSSMA17_1, complete sequence	87298-87332	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	CP032137	Acinetobacter haemolyticus strain sz1652 plasmid unnamed2, complete sequence	52562-52596	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP015366	Acinetobacter baumannii strain 3207 plasmid pAba3207b, complete sequence	59981-60015	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP017645	Acinetobacter baumannii strain KAB02 plasmid unnamed, complete sequence	9847-9881	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP020589	Acinetobacter baumannii strain 15A34 plasmid p15A34_1, complete sequence	10339-10373	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP020573	Acinetobacter baumannii strain 15A5 plasmid p15A5_1, complete sequence	69583-69617	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NC_010606	Acinetobacter baumannii ACICU plasmid pACICU2, complete sequence	55108-55142	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP042842	Acinetobacter baumannii strain ATCC BAA-1790 plasmid unnamed, complete sequence	15873-15907	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	CP007580	Acinetobacter baumannii AC30 plasmid pAC30c, complete sequence	35231-35265	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP019115	Acinetobacter baumannii strain MDR-CQ plasmid pMDR-CQ, complete sequence	34450-34484	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_KU549175	Acinetobacter baumannii strain C13 plasmid pC13-2 clone GC2, complete sequence	94420-94454	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_KX230794	Acinetobacter baumannii strain MAL plasmid pMAL-2, complete sequence	57574-57608	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP025267	Acinetobacter baumannii isolate SMC_Paed_Ab_BL01 plasmid pSMC_AB_BL01_1, complete sequence	4269-4303	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP020593	Acinetobacter baumannii strain USA2 plasmid pUSA2_1, complete sequence	56512-56546	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP020594	Acinetobacter baumannii strain USA15 plasmid pUSA15_1, complete sequence	18851-18885	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_KR535992	Acinetobacter baumannii strain A105 plasmid pA105-1, complete sequence	60647-60681	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP020582	Acinetobacter baumannii strain JBA13 plasmid pJBA13_1, complete sequence	48147-48181	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP026712	Acinetobacter baumannii strain AR_0063 plasmid unitig_2_pilon, complete sequence	40108-40142	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP017647	Acinetobacter baumannii strain KAB03 plasmid unnamed, complete sequence	36635-36669	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	CP002524	Acinetobacter baumannii TCDC-AB0715 plasmid p2ABTCDC0715, complete sequence	20860-20894	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_KM977710	Acinetobacter baumannii strain D46 plasmid pD46-3, complete sequence	65465-65499	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP026706	Acinetobacter baumannii strain AR_0056 plasmid tig00000059_pilon, complete sequence	69254-69288	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP017653	Acinetobacter baumannii strain KAB06 plasmid unnamed, complete sequence	56051-56085	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_KF669606	Acinetobacter baumannii strain G7 plasmid pAb-G7-2 clone GC1 (global clone 1), complete sequence	60649-60683	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_MK386681	Acinetobacter baumannii strain ABAY09008 plasmid pABAY09008_1B, complete sequence	63090-63124	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP024578	Acinetobacter baumannii strain AbPK1 plasmid pAbPK1b, complete sequence	69884-69918	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_MK243454	Acinetobacter baumannii strain 09A16CRGN0014 plasmid pCRA914-67, complete sequence	57426-57460	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP019218	Acinetobacter baumannii strain XH731 plasmid pXH731, complete sequence	25125-25159	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_MG954377	Acinetobacter baumannii strain SGH9601 plasmid pS21-2, complete sequence	61548-61582	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP038264	Acinetobacter baumannii strain LEV1449/17Ec plasmid pEC_gr6, complete sequence	48341-48375	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP035047	Acinetobacter baumannii strain ABUH793 plasmid p74.1Kbp, complete sequence	64640-64674	10	0.714
NZ_CP046703_18	18.2|7120652|35|NZ_CP046703|PILER-CR	7120652-7120686	35	NZ_CP033245	Acinetobacter baumannii strain 7835 plasmid pAba7835b, complete sequence	59982-60016	10	0.714
NZ_CP046703_9	9.11|4931515|34|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT	4931515-4931548	34	NZ_CP014682	Kozakia baliensis strain NBRC 16680 plasmid pKB16680_1, complete sequence	89035-89068	12	0.647

1. spacer 10.2|5414846|35|NZ_CP046703|CRISPRCasFinder matches to NZ_CP026690 (Nostoc sp. 'Peltigera membranacea cyanobiont' N6 plasmid pNPM8, complete sequence) position: , mismatch: 5, identity: 0.857

cttagctaaacaatatttagatgaaaaagccaatg	CRISPR spacer
gtcagctaaagaatatttagatgagaaagccaagg	Protospacer
 *.******* *************.******** *

2. spacer 10.2|5414846|35|NZ_CP046703|CRISPRCasFinder matches to AP018319 (Nostoc sp. HK-01 plasmid plasmid1 DNA, complete genome) position: , mismatch: 6, identity: 0.829

cttagctaaacaatatttagatgaaaaagccaatg	CRISPR spacer
gttagctaaacaatatttagatgagaaagctttgg	Protospacer
 ***********************.*****.   *

3. spacer 9.3|4930934|31|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT matches to AP014273 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S26-C46, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 7, identity: 0.774

atttacatttgttggatctgccttgaggaaa	CRISPR spacer
atttacatttgtttgatctgcatttgataat	Protospacer
************* ******* ** .. ** 

4. spacer 10.2|5414846|35|NZ_CP046703|CRISPRCasFinder matches to AP018319 (Nostoc sp. HK-01 plasmid plasmid1 DNA, complete genome) position: , mismatch: 7, identity: 0.8

cttagctaaacaatatttagatgaaaaagccaatg	CRISPR spacer
gtttgctaaacaatatttagatgagaaagctttgg	Protospacer
 ** ********************.*****.   *

5. spacer 14.3|5454492|30|NZ_CP046703|CRT matches to NC_012811 (Methylorubrum extorquens AM1 megaplasmid, complete sequence) position: , mismatch: 7, identity: 0.767

gaactccacgcttcccgccacgcctcgcac	CRISPR spacer
ccgctccacgcctccggccacgcctcgcgt	Protospacer
  .********.*** ************..

6. spacer 14.6|5454672|30|NZ_CP046703|CRT matches to NZ_CP027239 (Dietzia sp. oral taxon 368 strain W5195 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

gaactccacgcctcccgctacgccgaacgc	CRISPR spacer
gaactccacgccgccggctacgccgccgag	Protospacer
************ ** *********   . 

7. spacer 14.6|5454672|30|NZ_CP046703|CRT matches to NC_016587 (Azospirillum lipoferum 4B plasmid AZO_p4, complete sequence) position: , mismatch: 7, identity: 0.767

gaactccacgcctcccgctacgccgaacgc	CRISPR spacer
gccgccgacgccacccgcgacgccgaacgc	Protospacer
*   .* ***** ***** ***********

8. spacer 14.6|5454672|30|NZ_CP046703|CRT matches to NC_013858 (Azospirillum sp. B510 plasmid pAB510d, complete sequence) position: , mismatch: 7, identity: 0.767

gaactccacgcctcccgctacgccgaacgc	CRISPR spacer
gccgccgacgccacccgcgacgccgaacgc	Protospacer
*   .* ***** ***** ***********

9. spacer 14.6|5454672|30|NZ_CP046703|CRT matches to NZ_CP054617 (Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.767

gaactccacgcctcccgctacgccgaacgc	CRISPR spacer
gccgccgacgccacccgcgacgccgaacgc	Protospacer
*   .* ***** ***** ***********

10. spacer 6.7|2343287|34|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014203 (Clostridium baratii strain CDC51267 plasmid pNPD11_1, complete sequence) position: , mismatch: 8, identity: 0.765

tccaatctctaaaagttacagtagataaaaatgc	CRISPR spacer
caaaattattaaaaggtaaagtagataaaaatgc	Protospacer
.  ***. .****** ** ***************

11. spacer 18.7|7120654|33|NZ_CP046703|CRT matches to MT119360 (Enterococcus phage nattely, complete genome) position: , mismatch: 8, identity: 0.758

agcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
ttgattactaacaatttcaccatcaattttttc	Protospacer
   ****..******************* *. *

12. spacer 18.7|7120654|33|NZ_CP046703|CRT matches to MT119361 (Enterococus phage vipetofem, complete genome) position: , mismatch: 8, identity: 0.758

agcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
ttgattactaacaatttcaccatcaattttttc	Protospacer
   ****..******************* *. *

13. spacer 6.7|2343287|34|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT matches to MH595538 (Vibrio phage BONAISHI, complete genome) position: , mismatch: 9, identity: 0.735

tccaatctctaaaagttacagtagataaaaatgc-	CRISPR spacer
cggcgactcttaaagttagagtagat-aaaatgct	Protospacer
.   . **** ******* ******* ******* 

14. spacer 14.6|5454672|30|NZ_CP046703|CRT matches to NZ_CP023065 (Sinorhizobium sp. CCBAU 05631 plasmid pSS05631a, complete sequence) position: , mismatch: 9, identity: 0.7

gaactccacgcctcccgctacgccgaacgc	CRISPR spacer
agcttccacgcctcccgctgcgacgaagat	Protospacer
.. .***************.** **** ..

15. spacer 14.6|5454672|30|NZ_CP046703|CRT matches to NC_000914 (Sinorhizobium fredii NGR234 plasmid pNGR234a, complete sequence) position: , mismatch: 9, identity: 0.7

gaactccacgcctcccgctacgccgaacgc	CRISPR spacer
agcttccacgcctcccgctgcgacgaagat	Protospacer
.. .***************.** **** ..

16. spacer 14.6|5454672|30|NZ_CP046703|CRT matches to NZ_CP023072 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666a, complete sequence) position: , mismatch: 9, identity: 0.7

gaactccacgcctcccgctacgccgaacgc	CRISPR spacer
agcttccacgcctcccgctgcgacgaagat	Protospacer
.. .***************.** **** ..

17. spacer 17.2|6707991|35|NZ_CP046703|CRISPRCasFinder,CRT matches to LN885237 (Lactobacillus phage EV3 genome assembly, complete genome: monopartite) position: , mismatch: 9, identity: 0.743

ctgtaattccatagcgattaattacttttcagagt	CRISPR spacer
atttaattccatagtcattaattactttaatgatg	Protospacer
 * ***********. ************   **  

18. spacer 17.20|6707992|35|NZ_CP046703|PILER-CR matches to LN885237 (Lactobacillus phage EV3 genome assembly, complete genome: monopartite) position: , mismatch: 9, identity: 0.743

ctgtaattccatagcgattaattacttttcagagt	CRISPR spacer
atttaattccatagtcattaattactttaatgatg	Protospacer
 * ***********. ************   **  

19. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to MT119360 (Enterococcus phage nattely, complete genome) position: , mismatch: 9, identity: 0.743

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
acttgattactaacaatttcaccatcaattttttc	Protospacer
*    ****..******************* *. *

20. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to MT119361 (Enterococus phage vipetofem, complete genome) position: , mismatch: 9, identity: 0.743

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
acttgattactaacaatttcaccatcaattttttc	Protospacer
*    ****..******************* *. *

21. spacer 6.1|2342848|34|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT matches to EU545650 (Acidianus filamentous virus 9, complete genome) position: , mismatch: 10, identity: 0.706

tataggggatatggtagaagtgttagtgtagact	CRISPR spacer
agtaggcgatatggtagaagtgttagcacaagga	Protospacer
 .**** *******************...*..  

22. spacer 6.7|2343287|34|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT matches to MN694558 (Marine virus AFVG_250M9, complete genome) position: , mismatch: 10, identity: 0.706

tccaatctctaaaagttacagtagataaaaatgc	CRISPR spacer
tggtaatgctaacatttacagtagataaaaataa	Protospacer
*   * . **** * *****************. 

23. spacer 6.7|2343287|34|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT matches to MN694640 (Marine virus AFVG_250M10, complete genome) position: , mismatch: 10, identity: 0.706

tccaatctctaaaagttacagtagataaaaatgc	CRISPR spacer
tggtaatgctaacatttacagtagataaaaataa	Protospacer
*   * . **** * *****************. 

24. spacer 9.6|4931148|35|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040345 (Bacillus albus strain DLOU-Yingkou plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.714

gggaaatttaattcttttaatcctaaagtgctaac	CRISPR spacer
tataaatttaattcttttaatcccaaagaaggata	Protospacer
 . ********************.**** .  *  

25. spacer 10.2|5414846|35|NZ_CP046703|CRISPRCasFinder matches to NZ_CP018436 (Klebsiella pneumoniae strain MNCRE53 plasmid pMNCRE53_3, complete sequence) position: , mismatch: 10, identity: 0.714

cttagctaaacaatatttagatgaaaaagccaatg	CRISPR spacer
tgtagcaaaagaatatttagatgaaaacaatcctg	Protospacer
. **** *** **************** . .  **

26. spacer 10.2|5414846|35|NZ_CP046703|CRISPRCasFinder matches to NZ_CP018426 (Klebsiella pneumoniae strain MNCRE69 plasmid pMNCRE69_3, complete sequence) position: , mismatch: 10, identity: 0.714

cttagctaaacaatatttagatgaaaaagccaatg	CRISPR spacer
tgtagcaaaagaatatttagatgaaaacaatcctg	Protospacer
. **** *** **************** . .  **

27. spacer 10.2|5414846|35|NZ_CP046703|CRISPRCasFinder matches to NZ_CP036448 (Klebsiella pneumoniae strain KPNIH45 plasmid pKPC-e4b7, complete sequence) position: , mismatch: 10, identity: 0.714

cttagctaaacaatatttagatgaaaaagccaatg	CRISPR spacer
tgtagcaaaagaatatttagatgaaaacaatcctg	Protospacer
. **** *** **************** . .  **

28. spacer 10.2|5414846|35|NZ_CP046703|CRISPRCasFinder matches to NZ_CP045693 (Klebsiella pneumoniae strain TK421 plasmid pTK421_3, complete sequence) position: , mismatch: 10, identity: 0.714

cttagctaaacaatatttagatgaaaaagccaatg	CRISPR spacer
tgtagcaaaagaatatttagatgaaaacaatcctg	Protospacer
. **** *** **************** . .  **

29. spacer 10.2|5414846|35|NZ_CP046703|CRISPRCasFinder matches to NZ_CP018432 (Klebsiella pneumoniae strain MNCRE78 plasmid pMNCRE78_3, complete sequence) position: , mismatch: 10, identity: 0.714

cttagctaaacaatatttagatgaaaaagccaatg	CRISPR spacer
tgtagcaaaagaatatttagatgaaaacaatcctg	Protospacer
. **** *** **************** . .  **

30. spacer 10.2|5414846|35|NZ_CP046703|CRISPRCasFinder matches to NZ_CP028954 (Klebsiella pneumoniae strain AR_0141 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.714

cttagctaaacaatatttagatgaaaaagccaatg	CRISPR spacer
tgtagcaaaagaatatttagatgaaaacaatcctg	Protospacer
. **** *** **************** . .  **

31. spacer 10.2|5414846|35|NZ_CP046703|CRISPRCasFinder matches to NZ_CP014069 (Citrobacter amalonaticus strain FDAARGOS_165 plasmid unnamed) position: , mismatch: 10, identity: 0.714

cttagctaaacaatatttagatgaaaaagccaatg	CRISPR spacer
tgtagcaaaagaatatttagatgaaaacaatcctg	Protospacer
. **** *** **************** . .  **

32. spacer 10.2|5414846|35|NZ_CP046703|CRISPRCasFinder matches to NZ_CP022274 (Citrobacter freundii strain 18-1 plasmid pA18-1, complete sequence) position: , mismatch: 10, identity: 0.714

cttagctaaacaatatttagatgaaaaagccaatg	CRISPR spacer
tgtagcaaaagaatatttagatgaaaacaatcctg	Protospacer
. **** *** **************** . .  **

33. spacer 10.2|5414846|35|NZ_CP046703|CRISPRCasFinder matches to NZ_CP026384 (Serratia sp. SSNIH1 plasmid pSER-840e, complete sequence) position: , mismatch: 10, identity: 0.714

cttagctaaacaatatttagatgaaaaagccaatg	CRISPR spacer
tgtagcaaaagaatatttagatgaaaacaatcctg	Protospacer
. **** *** **************** . .  **

34. spacer 10.2|5414846|35|NZ_CP046703|CRISPRCasFinder matches to CP052538 (Klebsiella pneumoniae strain B16KP0141 plasmid pB16KP0141-1, complete sequence) position: , mismatch: 10, identity: 0.714

cttagctaaacaatatttagatgaaaaagccaatg	CRISPR spacer
tgtagcaaaagaatatttagatgaaaacaatcctg	Protospacer
. **** *** **************** . .  **

35. spacer 10.2|5414846|35|NZ_CP046703|CRISPRCasFinder matches to NZ_CP029724 (Klebsiella pneumoniae strain AR_0140 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.714

cttagctaaacaatatttagatgaaaaagccaatg	CRISPR spacer
tgtagcaaaagaatatttagatgaaaacaatcctg	Protospacer
. **** *** **************** . .  **

36. spacer 10.2|5414846|35|NZ_CP046703|CRISPRCasFinder matches to NZ_CP036437 (Citrobacter sp. ABFQG plasmid pKPC-e4b7, complete sequence) position: , mismatch: 10, identity: 0.714

cttagctaaacaatatttagatgaaaaagccaatg	CRISPR spacer
tgtagcaaaagaatatttagatgaaaacaatcctg	Protospacer
. **** *** **************** . .  **

37. spacer 10.2|5414846|35|NZ_CP046703|CRISPRCasFinder matches to NZ_CP036440 (Klebsiella pneumoniae strain ABFQB plasmid pKPC-e4b7, complete sequence) position: , mismatch: 10, identity: 0.714

cttagctaaacaatatttagatgaaaaagccaatg	CRISPR spacer
tgtagcaaaagaatatttagatgaaaacaatcctg	Protospacer
. **** *** **************** . .  **

38. spacer 10.2|5414846|35|NZ_CP046703|CRISPRCasFinder matches to NZ_CP027143 (Enterobacter hormaechei subsp. hoffmannii strain AR_0365 plasmid unnamed3) position: , mismatch: 10, identity: 0.714

cttagctaaacaatatttagatgaaaaagccaatg	CRISPR spacer
tgtagcaaaagaatatttagatgaaaacaatcctg	Protospacer
. **** *** **************** . .  **

39. spacer 10.2|5414846|35|NZ_CP046703|CRISPRCasFinder matches to NZ_CP043513 (Enterobacter kobei strain EB_P8_L5_01.19 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.714

cttagctaaacaatatttagatgaaaaagccaatg	CRISPR spacer
tgtagcaaaagaatatttagatgaaaacaatcctg	Protospacer
. **** *** **************** . .  **

40. spacer 10.2|5414846|35|NZ_CP046703|CRISPRCasFinder matches to NZ_CP026716 (Klebsiella oxytoca strain AR_0028 plasmid unitig_1_pilon, complete sequence) position: , mismatch: 10, identity: 0.714

cttagctaaacaatatttagatgaaaaagccaatg	CRISPR spacer
tgtagcaaaagaatatttagatgaaaacaatcctg	Protospacer
. **** *** **************** . .  **

41. spacer 10.2|5414846|35|NZ_CP046703|CRISPRCasFinder matches to NZ_CP016810 (Klebsiella pneumoniae strain DHQP1002001 plasmid p_IncFIB_DHQP1002001, complete sequence) position: , mismatch: 10, identity: 0.714

cttagctaaacaatatttagatgaaaaagccaatg	CRISPR spacer
tgtagcaaaagaatatttagatgaaaacaatcctg	Protospacer
. **** *** **************** . .  **

42. spacer 10.2|5414846|35|NZ_CP046703|CRISPRCasFinder matches to NZ_CP032893 (Enterobacter kobei strain WCHEK045523 plasmid p1_045523, complete sequence) position: , mismatch: 10, identity: 0.714

cttagctaaacaatatttagatgaaaaagccaatg	CRISPR spacer
tgtagcaaaagaatatttagatgaaaacaatcctg	Protospacer
. **** *** **************** . .  **

43. spacer 11.1|5414955|34|NZ_CP046703|CRT matches to MN694720 (Marine virus AFVG_250M584, complete genome) position: , mismatch: 10, identity: 0.706

atagattttgaattagtaacagttagtataaaat	CRISPR spacer
ggtgatgttgaattaggaacagttagtaaaccta	Protospacer
.  *** ********* *********** *    

44. spacer 11.1|5414955|34|NZ_CP046703|CRT matches to NZ_CP021787 (Acinetobacter baumannii strain A85 plasmid pA85-3, complete sequence) position: , mismatch: 10, identity: 0.706

atagattttgaattagtaacagttagtataaaat	CRISPR spacer
ttagattttggcttagtaacagttattgctgcac	Protospacer
 *********. ************* *.. . *.

45. spacer 11.1|5414955|34|NZ_CP046703|CRT matches to NZ_CP023028 (Acinetobacter baumannii strain 10042 plasmid pAba10042b, complete sequence) position: , mismatch: 10, identity: 0.706

atagattttgaattagtaacagttagtataaaat	CRISPR spacer
ttagattttggcttagtaacagttattgctgcac	Protospacer
 *********. ************* *.. . *.

46. spacer 11.1|5414955|34|NZ_CP046703|CRT matches to NZ_CP039024 (Acinetobacter baumannii ATCC 17978 substr. PMR-High plasmid unnamed1) position: , mismatch: 10, identity: 0.706

atagattttgaattagtaacagttagtataaaat	CRISPR spacer
ttagattttggcttagtaacagttattgctgcac	Protospacer
 *********. ************* *.. . *.

47. spacer 11.1|5414955|34|NZ_CP046703|CRT matches to NZ_CP039519 (Acinetobacter baumannii strain TG22653 plasmid pTG22653, complete sequence) position: , mismatch: 10, identity: 0.706

atagattttgaattagtaacagttagtataaaat	CRISPR spacer
ttagattttggcttagtaacagttattgctgcac	Protospacer
 *********. ************* *.. . *.

48. spacer 11.1|5414955|34|NZ_CP046703|CRT matches to NC_025109 (Acinetobacter baumannii strain A85 plasmid pA85-3 clone GC1 AbaR4 resistance island, complete sequence) position: , mismatch: 10, identity: 0.706

atagattttgaattagtaacagttagtataaaat	CRISPR spacer
ttagattttggcttagtaacagttattgctgcac	Protospacer
 *********. ************* *.. . *.

49. spacer 11.1|5414955|34|NZ_CP046703|CRT matches to NZ_CP015485 (Acinetobacter baumannii strain ORAB01 plasmid pORAB01-2, complete sequence) position: , mismatch: 10, identity: 0.706

atagattttgaattagtaacagttagtataaaat	CRISPR spacer
ttagattttggcttagtaacagttattgctgcac	Protospacer
 *********. ************* *.. . *.

50. spacer 11.1|5414955|34|NZ_CP046703|CRT matches to NZ_CP050404 (Acinetobacter baumannii strain VB2486 plasmid pVB2486_1, complete sequence) position: , mismatch: 10, identity: 0.706

atagattttgaattagtaacagttagtataaaat	CRISPR spacer
ttagattttggcttagtaacagttattgctgcac	Protospacer
 *********. ************* *.. . *.

51. spacer 11.1|5414955|34|NZ_CP046703|CRT matches to CP040043 (Acinetobacter baumannii strain VB958 plasmid unnamed3, complete sequence) position: , mismatch: 10, identity: 0.706

atagattttgaattagtaacagttagtataaaat	CRISPR spacer
ttagattttggcttagtaacagttattgctgcac	Protospacer
 *********. ************* *.. . *.

52. spacer 11.1|5414955|34|NZ_CP046703|CRT matches to NZ_CP015865 (Vibrio campbellii CAIM 519 = NBRC 15631 strain ATCC 25920, CAIM 519T plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

atagattttgaattagtaacagttagtataaaat	CRISPR spacer
aatttgttggaattagtaaaagttagtatatacc	Protospacer
*     ** ********** ********** * .

53. spacer 11.1|5414955|34|NZ_CP046703|CRT matches to LT605060 (Acinetobacter calcoaceticus strain NCTC7364 genome assembly, plasmid: 2) position: , mismatch: 10, identity: 0.706

atagattttgaattagtaacagttagtataaaat	CRISPR spacer
ttagattttggcttagtaacagttattgctgcac	Protospacer
 *********. ************* *.. . *.

54. spacer 11.1|5414955|34|NZ_CP046703|CRT matches to NZ_CP020594 (Acinetobacter baumannii strain USA15 plasmid pUSA15_1, complete sequence) position: , mismatch: 10, identity: 0.706

atagattttgaattagtaacagttagtataaaat	CRISPR spacer
ttagattttggcttagtaacagttattgctgcac	Protospacer
 *********. ************* *.. . *.

55. spacer 11.1|5414955|34|NZ_CP046703|CRT matches to NZ_MG954377 (Acinetobacter baumannii strain SGH9601 plasmid pS21-2, complete sequence) position: , mismatch: 10, identity: 0.706

atagattttgaattagtaacagttagtataaaat	CRISPR spacer
ttagattttggcttagtaacagttattgctgcac	Protospacer
 *********. ************* *.. . *.

56. spacer 11.1|5414955|34|NZ_CP046703|CRT matches to NZ_CP012008 (Acinetobacter baumannii strain Ab04-mff plasmid pAB04-2, complete sequence) position: , mismatch: 10, identity: 0.706

atagattttgaattagtaacagttagtataaaat	CRISPR spacer
ttagattttggcttagtaacagttattgctgcac	Protospacer
 *********. ************* *.. . *.

57. spacer 11.1|5414955|34|NZ_CP046703|CRT matches to NZ_CP012005 (Acinetobacter baumannii strain ATCC 17978-mff plasmid pAB3, complete sequence) position: , mismatch: 10, identity: 0.706

atagattttgaattagtaacagttagtataaaat	CRISPR spacer
ttagattttggcttagtaacagttattgctgcac	Protospacer
 *********. ************* *.. . *.

58. spacer 11.1|5414955|34|NZ_CP046703|CRT matches to NZ_MK941846 (Proteus mirabilis strain PM1157 plasmid pOXA-23, complete sequence) position: , mismatch: 10, identity: 0.706

atagattttgaattagtaacagttagtataaaat	CRISPR spacer
ttagattttggcttagtaacagttattgctgcac	Protospacer
 *********. ************* *.. . *.

59. spacer 11.4|5414955|35|NZ_CP046703|PILER-CR matches to MN694720 (Marine virus AFVG_250M584, complete genome) position: , mismatch: 10, identity: 0.714

atagattttgaattagtaacagttagtataaaatt	CRISPR spacer
ggtgatgttgaattaggaacagttagtaaacctat	Protospacer
.  *** ********* *********** *    *

60. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP021787 (Acinetobacter baumannii strain A85 plasmid pA85-3, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

61. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_MG954379 (Acinetobacter baumannii strain SGH0905 plasmid pS32-2, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

62. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP020577 (Acinetobacter baumannii strain SSA12 plasmid pSSA12_1, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

63. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP023028 (Acinetobacter baumannii strain 10042 plasmid pAba10042b, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

64. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to MK531538 (Acinetobacter baumannii strain MC23 plasmid pMC23.1, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

65. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP027243 (Acinetobacter baumannii strain WCHAB005078 plasmid p1_005078, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

66. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_KY022424 (Acinetobacter baumannii strain Ab8098 plasmid pAb8098, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

67. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP035052 (Acinetobacter baumannii strain ABUH763 plasmid p74.1Kbp, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

68. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP017657 (Acinetobacter baumannii strain KAB08 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

69. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP012008 (Acinetobacter baumannii strain Ab04-mff plasmid pAB04-2, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

70. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NC_025111 (Acinetobacter baumannii strain D72 plasmid pD72-2, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

71. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to CP033518 (Acinetobacter baumannii strain 2008S11-069 plasmid p2008S11-069-2, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

72. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_KF889012 (Acinetobacter baumannii TYTH-1 plasmid pAB_CC, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

73. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP032742 (Acinetobacter baumannii strain C25 plasmid unnamed2) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

74. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NC_025109 (Acinetobacter baumannii strain A85 plasmid pA85-3 clone GC1 AbaR4 resistance island, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

75. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP016302 (Acinetobacter baumannii strain CMC-CR-MDR-Ab66 plasmid pCMCVTAb2-Ab66, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

76. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP016297 (Acinetobacter baumannii strain CMC-CR-MDR-Ab4 plasmid pCMCVTAb2-Ab4, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

77. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP033857 (Acinetobacter sp. FDAARGOS_493 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

78. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NC_017163 (Acinetobacter baumannii 1656-2 plasmid ABKp1, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

79. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP050392 (Acinetobacter baumannii strain VB11737 plasmid pVB11737_1, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

80. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP050413 (Acinetobacter baumannii strain PM192696 plasmid pPM192696_1, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

81. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP017649 (Acinetobacter baumannii strain KAB04 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

82. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP050404 (Acinetobacter baumannii strain VB2486 plasmid pVB2486_1, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

83. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_LT984690 (Acinetobacter baumannii isolate K50 plasmid I, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

84. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP029571 (Acinetobacter baumannii strain DA33098 plasmid pDA33098-71, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

85. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP039994 (Acinetobacter baumannii strain TG22182 plasmid pTG22182_1, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

86. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP008851 (Acinetobacter baumannii strain AC29 plasmid pAC29b, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

87. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP014216 (Acinetobacter baumannii strain YU-R612 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

88. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP017655 (Acinetobacter baumannii strain KAB07 plasmid pKAB07, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

89. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP023030 (Acinetobacter baumannii strain 9102 plasmid pAba9102a, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

90. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP023030 (Acinetobacter baumannii strain 9102 plasmid pAba9102a, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

91. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to CP040043 (Acinetobacter baumannii strain VB958 plasmid unnamed3, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

92. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP050915 (Acinetobacter baumannii strain DT-Ab007 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

93. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP050909 (Acinetobacter baumannii strain DT-Ab022 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

94. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP008707 (Acinetobacter baumannii strain AB5075-UW plasmid p1AB5075, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

95. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP017643 (Acinetobacter baumannii strain KAB01 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

96. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP023033 (Acinetobacter baumannii strain 7847 plasmid pAba7847b, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

97. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to CP014292 (Acinetobacter baumannii strain AB34299 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

98. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP027121 (Acinetobacter baumannii strain AR_0056 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

99. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP030109 (Acinetobacter baumannii strain DA33382 plasmid pDA33382-85, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

100. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP017651 (Acinetobacter baumannii strain KAB05 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

101. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP020580 (Acinetobacter baumannii strain SSMA17 plasmid pSSMA17_1, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

102. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to CP032137 (Acinetobacter haemolyticus strain sz1652 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

103. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP015366 (Acinetobacter baumannii strain 3207 plasmid pAba3207b, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

104. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP017645 (Acinetobacter baumannii strain KAB02 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

105. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP020589 (Acinetobacter baumannii strain 15A34 plasmid p15A34_1, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

106. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP020573 (Acinetobacter baumannii strain 15A5 plasmid p15A5_1, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

107. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NC_010606 (Acinetobacter baumannii ACICU plasmid pACICU2, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

108. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP042842 (Acinetobacter baumannii strain ATCC BAA-1790 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

109. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to CP007580 (Acinetobacter baumannii AC30 plasmid pAC30c, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

110. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP019115 (Acinetobacter baumannii strain MDR-CQ plasmid pMDR-CQ, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

111. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_KU549175 (Acinetobacter baumannii strain C13 plasmid pC13-2 clone GC2, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

112. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_KX230794 (Acinetobacter baumannii strain MAL plasmid pMAL-2, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

113. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP025267 (Acinetobacter baumannii isolate SMC_Paed_Ab_BL01 plasmid pSMC_AB_BL01_1, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

114. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP020593 (Acinetobacter baumannii strain USA2 plasmid pUSA2_1, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

115. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP020594 (Acinetobacter baumannii strain USA15 plasmid pUSA15_1, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

116. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_KR535992 (Acinetobacter baumannii strain A105 plasmid pA105-1, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

117. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP020582 (Acinetobacter baumannii strain JBA13 plasmid pJBA13_1, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

118. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP026712 (Acinetobacter baumannii strain AR_0063 plasmid unitig_2_pilon, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

119. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP017647 (Acinetobacter baumannii strain KAB03 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

120. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to CP002524 (Acinetobacter baumannii TCDC-AB0715 plasmid p2ABTCDC0715, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

121. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_KM977710 (Acinetobacter baumannii strain D46 plasmid pD46-3, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

122. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP026706 (Acinetobacter baumannii strain AR_0056 plasmid tig00000059_pilon, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

123. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP017653 (Acinetobacter baumannii strain KAB06 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

124. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_KF669606 (Acinetobacter baumannii strain G7 plasmid pAb-G7-2 clone GC1 (global clone 1), complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

125. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_MK386681 (Acinetobacter baumannii strain ABAY09008 plasmid pABAY09008_1B, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

126. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP024578 (Acinetobacter baumannii strain AbPK1 plasmid pAbPK1b, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

127. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_MK243454 (Acinetobacter baumannii strain 09A16CRGN0014 plasmid pCRA914-67, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

128. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP019218 (Acinetobacter baumannii strain XH731 plasmid pXH731, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

129. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_MG954377 (Acinetobacter baumannii strain SGH9601 plasmid pS21-2, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

130. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP038264 (Acinetobacter baumannii strain LEV1449/17Ec plasmid pEC_gr6, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

131. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP035047 (Acinetobacter baumannii strain ABUH793 plasmid p74.1Kbp, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

132. spacer 18.2|7120652|35|NZ_CP046703|PILER-CR matches to NZ_CP033245 (Acinetobacter baumannii strain 7835 plasmid pAba7835b, complete sequence) position: , mismatch: 10, identity: 0.714

aaagcattatcaacaatttcaccatcaattgtcac	CRISPR spacer
aaagcattatcaaaaatttcagcattacctacaga	Protospacer
************* ******* ***.* .*.. . 

133. spacer 9.11|4931515|34|NZ_CP046703|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014682 (Kozakia baliensis strain NBRC 16680 plasmid pKB16680_1, complete sequence) position: , mismatch: 12, identity: 0.647

tagcaataccactcggtgaagttccagaggtagc	CRISPR spacer
ctgcagtaccactcggtgaaattccaattcgttt	Protospacer
. ***.**************.*****.      .

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	409936 : 492313	43	Tupanvirus(37.5%)	transposase,protease	NA
DBSCAN-SWA_2	553986 : 640842	55	Tupanvirus(38.46%)	transposase,protease	NA
DBSCAN-SWA_3	1291643 : 1327239	36	Streptococcus_phage(25.0%)	transposase	NA
DBSCAN-SWA_4	1893167 : 1946358	47	Bacillus_phage(33.33%)	transposase,tRNA,bacteriocin	NA
DBSCAN-SWA_5	3668351 : 3726015	42	Paenibacillus_phage(33.33%)	transposase	NA
DBSCAN-SWA_6	6496978 : 6567177	59	Bacillus_phage(36.36%)	transposase,protease,tRNA	NA
DBSCAN-SWA_7	6595657 : 6628147	28	Brazilian_cedratvirus(25.0%)	transposase,plate,tail	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP046703|409936:492313|DBSCAN-SWA
AATACAATTAACAGATTCATTGAAAAAGTTATTGAAGGAAACCGCACATCAATTAAAGGGAGCAGCTAAACGTAGGTTCATTGCACAAACAGTTGTGGCATTAAGACACGGAGGAAAGTCTATAGCAGAGCGAGAGTTAGGATGGAACCGTGTAACTATTGGTAAAGGAATTAAAGAATTAAATAGTGGTATCACTTGTGTGGATAATTATCAAGGTAGAGGAAGAAAAAAAGCAGAAGAACACCTACCAACTCTTTTAGAAGATATCAAAAAACTAGTCGATTCTCAAAGTCAAATAGACCCGACTTTTAAAAGTCAAAGACTCTATACCCGACTGGGCGCATCTGTTGTAAGACATCAATTAATTGAAAAATTTGGTTATGCTGAAGAAGAATTACCAACTTCAGAAACAATTCGTGTCAAGTTAAATGATTTAGGGTATCGCCTCAAGAGGGTTGCCAAAATTCAACCTCAAAAAAAATTCCCGAAACTGATGCAATCTTTGAGCAATTAGCTATAGTTCACCAAGAAGCTTCAGATGACCCAACTATTTTACGTTTAAGCTTGGATGCGAAAGCTCGCGTAAATATCGGCTCCTTTGATCGTGGTGGTAGAAATCGAGTACCAACAGAAACTGATGACCACGACTTCAAACCAAAAACAACTGTAGCTCCTTATGGTATCTTTCTTCCAGACCTTGACGAGCTATTTTTGTATTTTACAGAATCCAAAGTAACTAGCGATTTTATCGTTGACATTTTAGGGGATTTTTGGAAATCAGAAAGCTGGCGATTTTCGGAAATAAAAACTTTACTTATTAATCAAGATAATGGAGGAGAAAATAGTTCTCGACGTACTCAGTTTATGAAACGTATAGTTGAATTTGCTCAATCATACAAATTAAATATACGTTTAGCTTATTACCCTCCCTATCACAGTAAATATAATCCAATTGAAAGAACTTGGGCTGTTTTGGAGAATCATTGGAATGGCAGTATTTTAGACGATGTGGAAACTGCATTAAATTTTGCTAAGACTATGACGTGGAATGGTAAAAGTCCAGTTGTTAAGTTAGTTACTCAGACTTACTCTAGCGGAGTCCGTCTAACTAAAAAAGCTATGCAAGAAATTGAAAATAAGATTGAACGTTTGACTAATTTTACCGAAGATAATTTACCAAATTTAGGTAAGTGGTTTATTGATATCTGTTGTGGAGTAACGTAATTTTCAAAAAGTTAAAAGCGCAAAAATAGTCGATAGCAATTCAGCTCACTGCATTTAAGAACTCTCTTTGTGCAGACATTTATCTTGCCTATTTATTGAGGGAGAAAGGGGTTGCCGTTGGCAACCCCTTTCTCCCCCTTAAAATGATTATCATTTTTATTGACTGTATATTTTATTCTCTGGAAGTCCCTAAGAGATGGGGCCTATTTTCGTTAAAATTCTGTCGCCACTCCCCTACAACATTTAAATTTCCCGTCAAAAATCCATTTTTGCAAGCATGACGCTGAATCTTACCACTGGATGTCTTTAATATACTCGCCGTCTTAAGCAGCAATACCGCATAAACTTGTAACTCATGCTGCTCTGATACAGCTTCACAGATTGCTCCAACTAACTCATCAACATTCAGTTCCCGCAGGTAATTGCGATGCACTTCTTGAACTACAACTAGTCTTTCTTCTCCTTCTACTTCCACAGCAAACGCAGCACCCCAATCAGGTCTTAAAGCTGGGTGACTCTGCTGCACCGTCAGTTCAATGTCTTGAGGATAATGGTTGCGACCTCTAATAATAATTACATCTTTGAGCCGCCCAGTGATAAACAACTCACCATCCTTTAAAAATCCCAAATCCCCAGTACGTAGAAACGGTTGTTCTTTAGTGCCTCGTAATTGTGCCTTAAAGGTTTCCTCAGTCTGCTCTGGTCGCTGCCAATAACCCTGAGTTACACTACGTCCTGATATCCAAATTTCCCCGACTTGATTGAGAAGGCATTGTGTTAGGGATTCTGGGTCAGCGATGACGATTTTGGTATCAAGCCATTCGCATCCACACCCTACTAACTGCCTCACATTTTGAGTATTCGATGATGCTTCGACAATTTGATTTTGTGCTAATTCATCAGCTTTAACAGTACAGTAAACTGGCTCTGCTTCACCTAGTCCCCCAGAAATCATCAAGGTTGCTTCAGCCATGCCATAACAGGGATATAAGAAGTTAGAACGGAAACCACAAGGCTGGAATTTTTTGGCAAATCGTTCTAAAGTATGGCGGCGGACGGGTTCTGCACCATTGTAGGCAAAACGCCAAGTGCTGAGATCGAGGGTTGCTAATTGCTCCTGTGTAATCCTGTTGATGCACAGTTCATAGGCAAAGTTCGGGCCACCCGAATGGGTTGCGTTATAATGTGAAATTGCCTGTAGCCACCGAATGGGTTGCTGCACAAAGGCTGTTGGTGACATCAAGATGACTGGTACTCCTGTGTACAGGGGTTCGAGAATCCCCAAAATCAGCCCCATATCATGAAAACTAGGTAGCCAAGATACAGCCACACTAGCTGGTGTGAAGGCAAATGCTTGCTTCATGTATTCACAGTTATGCAGCAAGTTGTCGTGACTCACCATCACTCCTTTTGGTGTGCCTGTAGAACCAGATGTATATTGCAGAAAAGCTAAATTCTCGCTGTTAATTTCCGATTTTTGCCAATTTTTGGCTTGGTTGCTATCTATATTATCTGTAGCCAGAATGTGTAGTGTATTTAGTTCTGAGTTTTGGTCAAAGCTACGCTTTATATTCTTTAACAGTGAATTAGTTGTGAGTACAATCTTTGCTGAAGCATCGGACACAATCGCAGATAACCGCGTCATTTTTTGATTTGGTCGGGGTGGATAAGCTGGTACGGCTATCACACCAGCATATAAGCATCCAAAAAAAGCAGCGATAAATTCTAGTCCTGGTGGATAAAGTAATAAAGCTCGTTCACCCGTTAATTCTAGAGATTGTAACTGGGAAGCGATCGCTCGTGACAGTATATCCAACTGTTGATAAGACAGTCTAAGTGTTTCTTTTTCGCCTTCTTGAAGAAAGATATAAGCTATTTTGTCAGGCTGATGTATTGCTCTATAACTCAGAAGCTCTATCCAAGTTAAAAATTTAGACATAAATTTTTGCTAGCTCTCATGTGGCTTAAAGTAAGATTTTGCTGTTTTTGAGAAAAGTCTATTTTCTCACTCCAAAGGCAAGGCGATGCCTAAATCATTCCTATTTCTGACCCTAAGCAATGTGCTTCTTAAGAGATAATCGATTTTACATGGATTGCCTTGGTGAACGCATCGTATATTTGTCCTATTTTTGACTAGGATCAACGACCTATATAAGTGTTAATTATGAATAGAAAATAACCTCAAGAGCCTATAAGCTTAATTCTCGACTCCTTCCCTCTCCCCCTATGCACGATTATCATCTTTATTTAAGTGGTTTTGAGTATTTGGACTGATTGACAAAATGCACTTTACCTTAACCTCTCACGGATGCTCAGTAGAGTATTTTTGTGAAAGTGCGCCTAATGTAAGCGATCGCTTCTCCCCTATCCTTGTTACAACCGCGCCTCCACAGCCGACGATTGCTCCTTGGGGTAATGGTGGATTTATGTTTGACAAATGAGTGATAACCATTGGTTAACACGCATTCAGCTAAGGGTGTTGCATTGGGCTTGGTTTATTGCGTCTAATCCTTGCATAGTGAAGCTTTAAAAGTTTTTCGCTCTTTTTACGGAAAGTACAAAACTTGAATAGATAATGTAAAGGCGTTAAGTTGCTGTAACGCTCTTTCGGTTACTTCGCAGAATTCAGGCGATATTAATATCATTCACACATTTGGACTTGAGATATTGCAAAACCTCTTGATATATCTGACTGCTAACGCGATCGCCCCTTCTACCATTCTCTAATTTAATATCATCAACGAAGAAATTGAGCTTAAATTCAGCATAGGTAATCCCATCATCGCTATGATTTGTACCTTTGATTAAAACTTGTGGTTCTTGCCACTTTTGTCGCGGTTCTTTGAATCGTTCCCGAACCCATTTATTTAATTCCATTACATAATCATCAATCCGAGTTTCTTCACTTTGGGGATTAGAAATTTTTTGGTATAAACGCTGCGATCTTCGCTTGAGTAGATTAAGTTTACGTTCCCACTCTTCAGAAACCATGTAACTATCATTATCCAAGAGATTTGGATCGCGAATCCAGATGCGATACCATTCCCGGACTAACTCAATCAACGAATCTTGAACTCTGATTTCTTGCAAGTTAAAAATAGTACGATTGTTTTGAGCTTCCGCAATTGCTTCTAACCCAATCAAAGCTAGTATATCCTTATACTCCTGCTGTACATTATTAATTTCATCTTGAGTTAACCCACCCTTTTCGGCAAACTGGAGTGTAACAACTAGTGTTTCTAGTCCTATTTGAATCTCTTCTAATTTATAGTTAACTTCCTGTTCTGCAATTAAGCGCAATTTACCTATTTTTTGTTGTTCTGTTAGTTCATCAATTTGATAGTAATCATCAAATATTTCTAATTTTTTATCAATATCTCCTAACGTATCTGGATGAGATAGAATAATTTTTACTATCATCTGTTTAGCTTCATACATATCGTACTTGACTAATACTTCTACCTGACTGGAGTGATGATAATAAGCTGTAGGACGGCTGAGGTTAATAATATTCTGGCTTTGTAAATTACTATTAGGAATATAAATATTATAATGTTTGTCAGGTACATAAAGTTGCGTAACCCGTACACCAATTTTTCTTAGTATGGCAATAGAACCGTCCTCAAGTCGCAAAACATCACCAAACTGGAAGGGTGTATCAATCAACAACACAACACCACTAAAGAAGTTTGCCAGGATGCCTTGAGCTGCAAAACCAATTACAAATGTCGCACCACCTAAAGCTACCCAAATACCAGTAAGATCGACTCCAAAGGAACGTAAAACCAAAAAAGCAGCTATCAAGTAAATTACAACAGGAACTACTGCTTCTAAGAGAGGTAGTAGCACATCGTCCCACATGGCTTCTGTTTGTTGAGTATACTGCTTCAGGTAATAGATAAAAACTTCAATAAAAATTTGTACTATCCAATAGCTAATTGATATGATTATTCCGGCTGTTATGATATTCTCAAAGCTGTCAATCACTGTACCTGAAGGCAGACTCTCGAAGGTTAATTTTAGGACACCCAACACAAAAGTAGCTAGAGCCGGATAAGCCGAAACGTTAAGGGTAACTAGGGCAATATCTCGTTCAAATTTGCGAAAAATAGAACGCAATACATAAAATAAAATGACGTAAAGTAAAATGCCGCCAACAAATGTGATTAGTAAGCTACTCACAACGAAAGCCCAAGTATTTGTTTCAAATGGTAAAAATTTGTTTAGCATTGTAGTAGTTTTATTGCTCTAATTTATAATTGTTTCATGACATTAAATTTATCTTAGATCAAAAGATAATGTTTAAAACCCTCATCAGATAAGGGCTTTAAATATTATAAAAGCTATGTAGTATAATAAGTACCGAAGAGCCTAAAAACTAACGTTCAACAGTAGCAATGCTTTAAGATTTTTAGTATATTTATTATTCAATTTCGAGTTTGAGTCCAGGGAGTAAACGTTCTAGATTTTTCAAGGATTTTCCTTGCCAAGGCATAGTATTTGAACCTAAAACAAGCAACTGAATTCCTTTTTTCTTACGCAAGCTCAGGACAAATTTTGATAACATACTAATACCAGAACTATTGAGAAATGCTAAATCTCTTAAGTTCAAAGTCATCGTTGCAGGATCGGTTGCAGCAATTTTATTGAGTAGATTGGTAATTGGTTCATATTCACTCGATCCCCCAAGGCTCAATTCTCCTTTAAAGTTGACTGTTGCAGAGTCTGTATCAGCTTCAACGGTATAATCTCCATCTTTAATCTCTTGCAAAACCATAATATGTTCTTTTCCTAAATAAACAATGTTTGAATCAGATACCGACGAGTACTATACCTTAAATTGTGCCATTGTAGTTACGGCCATAATTATAGATTCTTGCTGAATAGTTTCTAATTTCCAACCAATTTTGGCTGAGTAGTCATTAATCATGGTTAATAGTCCTAAGCCAGAAGTTCCATTTTTTTCAGCGCTTTTTTCAACTTGATGCACAAACATTTCATGGGTATTTGAAGTTAAGATTTTTTCAATAACTGCCCTCAATTTAGCTTCAGTTTCCAATTTAATACTATTGCTGGCGAAAATCACCGCAGTGACACTATCTGCGTTATTCAAAAAATGAATACCAATTCTTACTTTGTAGTTAGAACTATCATCATTAAACTTTATGGCATTTTCTAAAAGTTCGTTGGCGACATAGCTAACAGCACTTTTATTTTCTTTGATTATTTGTTCTTGATTTGGTTCATCTTCATCTACAGCTAAAAAGTTGGCAAAGTAGTCTGCAAAAAAATGTGCTGAAAGACGATTGCTACGCCAACGTTGTTTGATTGGGCGAGAACTGGGTGTAAAATAAAGTTCAAGAGAATCATGTTCTGGAGGAAAGTCAGAGATCAGATCACCAAATGATTCAGTTTTGATTATAGTAGAGACTGTAGATATTGGGAGCATACTTTTTTAATCTCAAAATAATTGTACATGAATGCAGGTTAAGCGCCAATAAGAAAAGTTTTAAAAGGTAAGAATTCAAAAGGCAGAATAGTTAAATAATCAAAAAAATTTTTATGAATAAATATATTAGGCATTCAAGATTTCTTATAAATTATGACTCTTGAATTCTGGATACTGAATTCTTATTTTAAAAATTGAATTTAATGATTTAATACCACAATTATGCAATGCCCAATAAGCTAAAATCTAAGTCGATGATCGTATAGCAGTTTTAAATCATTTTTTAAATAAATTAACTGTAGAGGCACAGAGAGGAAATTGGAGATTTTCATGACTCATTTTGGATTGCTAGAGCATTTTTTATATTTGTCGATATTAACTTTCAGAGACTTCTTCCTGTCGCTTGAATACTAGCAATGTGATGTCATCAAATACTTTTTGTTTACCAATATGTCGTCGCACATCTAAAATTACTGCATCTTTAATTTCTGATGCTGATTTGTGCCAGTTGTGACTGATTATTTCACATAACGGTTCAAGTCCGTATTGATTTTTATTGATGTCTTTGGCTTCGGTAATACCATCGGTGTAGAGGACAACCCCATCACCTGGTTGTAATTCCAGGGTTATATCGCTAATAAAATCAGTTATGTCATCATCTAAACCAATGGGGAAACCCAAGTCCATCGTGTCAATAAGCTCAATTTGCCCACCTTTGCGGATGATGATTGTTTCTTCGTGCTGTCCACTGATACTTATTTGCCCTTGAGCATAGTTGAGAATCACCAATGTCAAGTTCTTCTCAGAGTTCATCCGTTGCACGTTCTTACAGATGGTGCGGTTGAGTGTGTCAAAGAAGCGCACTGAATCAGATTCGCGGATTTCTTTGAGGAGGCGAACTGCTGTTTGTGTCATTAACATTAACAATCCACTTTCTAGTCCATGTCCAGTTACGTCTCCAATACCAAGAGTTACTACTCCGTCGGTGTGCAGTACATCGTAGTAATCGCCGCCGACTTCATCCGCAGCTTCCATAAAGCCAGCAATATCTAGTCCTTCAATAGCTTCTAGTTCTTCTGGTTTTGGGAGAATCATCTGTTGCATTCGCCGAATTATATCGAGTTCGGCACTCATGCGGAGGTTTTCTCCTTTGAGTTTTTCATTGAGAATATTAATTTCTTCATTAGCTTCGGCTAGTTCAGCAGTGCGTTCTTGAACTTTAATTTCTAGATTGTGGGCATAATCTTCCAATTGCCGATAGGAAAGCATCAGATTTTTCCATAAAACCTGTACAAGACCAATTATTAAGGCGCTGATAACAGTTAATAATGGTGTAAATACAGGAATTAACCAACCACCAAGAAAAGCAATGTAAGCACTGCTAAAAATAATCACCACAGCTAGTAATAAACCACCTATGGTCAGCCAACGTTTTTTAATATAAATTGTGCCAAAGGTGGCACTGTATCCAGACCAAAAGATGATTAAGAACCAGTTTAGAGGTTTAACGATAGCTCGCATCATTGGGCGGCCATCTATGGCGGCGCTGAGAATCTGACTGGTAAGATTTGCGTGAACTACTACTCCAGGGACTAGCTCTGTAGGAAAAAATAAATTGCTATTGTAAGGTGTACTATAGCTATCATTTAAACTGGGAGCTTTTGCACCGATCAAAACTAGGCGATCGCGTATAAAATTAGCAGGTATGCGATTTTCTAAAACATCGGTCATGGAAATATGAGGAAAGCTCTCTAGCCCACCTCGATAATTAATTAAAACTTGATATCCTCCCATGTCAGCTTCGTTGTATTGCCCATCATTGCTAGATAGAGGTACAAACTTAGCTTTACCTAAACCGTAGATTTGTTTATCTGCGTTGATTGATTTTAATTCAATGCCTGCTTTTTCTAAATATATTAAGGCTAGTTTAACTCCTAGCCCTTGAGCTAAACTTTGATCGGGTTTACCTAATAAAATAATACCGCGTCGGATTTTGCCATCTGTATCTAAGAGTAAGTCGTTGGCAGCTACTTGACTCTGTTTAGCTAAAATTGGTGGTGGTGCAACTGGTTTTCCGGCAACTTTTTCAATGCCAATAAAATTGGGAGTATTTTGAAATTCTTTGACGAGTTCTGCGTGTCCCGGTTCTACAGGTAAATCTCGATAAATATCGATGGCGATCGCTCTTGGTTGTTGTGCTTTGATATTGTGAATCATTTTCGCCATAACGCGATCGGACATCGGCCATTGCTTGACATATTGAATATCTGGCTCATCAATTGTGACAATCACAATTCGTTTGTCTATAGCTTCTTGCGGACGAATACGAAATAATTGATCTAAAGTTACCCATTCTAAAATTCTAAAAACACCTATATTACTCCCTGCAATGACCAATCCGGCAACACAGGGAGTAATTATCAGCGTTCCTTGCCATTTTTTAAGTGATTTTTTGAGTTTTTGCCACATTATTCTTCAAAAAGCGTCTGTCAATGGTTGAGAGGCAATATTTTCTAGTCCAACTTGCTTGAGTAAATCGTGCCATTCAGTAGCGAAAGCTTTATTATTTGGTTGCGATCGCTTTGCCGCCGCTAAAATTTTTAGGGTATCATACCATACACCAGCCTCAGCATATTTAGTGGCTAATTCCACAGGAGATGAGGCTAACTCCTGCTCATTAAATGTAGCCTTGACTCGTTTTATCCACCCTGTTACAGAATAATTATCAGGTCGGAGAATTCCGCCTGGTTCAATAGGTGCAAAATACCACAGGTAATTTTTATCTATTACTAAAGGTGGTGCTGCTGGAGGTAACGTAATACTAACTACACCACCATCGGGAGGAACTTTTAGCATTGTCGAATAATGGGGATTTCCGTCTTCGTCTTGGAGGCTGAAAAATACGGTTTCTGCGCCAACTGGAGGCAAATAGACAAAAATTGTGGGGCTTGCTAATACAGTGCGTCCCTGTTTGGTAGGGGGAACTAATGCTGTTAATGGTGCAGTTTTTCCCCTTGTACCACCACCGATGCTGCTTCTGGGGGTTGAATTTCCACTAGGTAGAGTCAATTGCACATCACCCCTGGTTCCGCCGCCAACGCTGGTTTTAGGTGTTGAACCTCCTGGTAAAGCAAATTGCACATCGCCCCTGGTTCCGCCGCCAACGCTGGTTTTAGGTGTTGAACCTCCGGGTAAAGCAAATTGCACATCGCCCCTGGTTCCGCCGCCAACGCTGGTTTTAGGTGTTGAACCTCCGGGTAAAGCAAATTGCACATCGCCCCTGGTTCCGCCGCCAACGCTGGTTTTAGGTGTTGAACCTCCGGGTAAAGCAAATTGCACATCACCCCTGGTTCCGCCGCCAACACTGGTTCTAGGTGCTGAACCTCCGGGTAAGGTGAATTGGACTTGTCCGCGAACGCCACCGCCAACACTGGTTTTGGGGGCTGCATCGTTGGGAAATTTAAATTCCACACTAATGAGAACTTGATTGGTAACAGTTGGTTTCTCTTGATAGAGAAGGCTTGCTAATGTAGAATTGCTTGTCAAAACTATTAATGTGCCGCTAATAGTGAAAAATAAAAATATTTTAGAATTAAACTTAACCATACTCACCTCTTATGCTACGTTTACAACCAATTACCGACAAGAACGAAAGAAGACCAAAAATAAGGATGTTTGTATAAAGGATTAGCCATAATTTTGATTTGTGCCTGTTGCAATGCCTCAGCTTTGTTTAGTTTTTGATTACTCAATTGGTGATAAAATTCTTTCATTAAGGAGGAAGTAGACTCATCACTTACTGACCATAAACTAGCAAGAGTACTTTTAGCACCAGAACGCAAAGCAAATCCAGCTAAACCTAAAGTTGCACGATTATCACCTACGGCTGTTTGACAAGCACTCATCACTAATAATTCAATCGGTTCTACGTTTGTTTGACTTCTGTTTTTAAACAAAAGATCAAAATCTTGAATGGAAATGCGATCACCCCAGGTCAACAAAAAGGTTTCTTCTGGGTTGGAACTGAATTGACCGTGAGTAGCAAGGTGAACTATGGGGAAAGATTTATTAGCGATCGCCGCTTTTAAACTGTCTCTGCTAAACTTCTTATCTAGCAACACTTGGGAATTAACTTCTGTCGTAACTTCTTTAATTTCTTCTGTAACTCCAGGTAGGGGATTGAAGCCTTGGCGTGCTTCCGTTAATCCAGCCGCTAACACGCTCAATTTTTGGCGTTGCAGTCCTTGAGGAAATAGTTGTAATCCAGGACTGAGAACAACACTATAATTTTCGATTAAATACTGTTTGCCATCATACAGAACAGCCATTGGCAAGTTTCGCAATAAACTATCTGGAATGAAAACTAAAGTTTTGATATTACTTTTCTGGAGTGTTGCTTGAGCAGGTGCAACCAGCCAGTTATAAATTTCTTGGGAGAGTCGCAAACGCTCGTTACTGGGATAACCAGGGGATAGGGAAGAATAAAGTTGTTTTAAGGTAGCTTCTATTTGCTGTTTTGGTAGTTGGGTGCTGTAGTGACGCAGAGGTTGATTAGGAACTGAAAGAATGACTTCCAGGCGATCGCTTAAAATAATTGGATAAATAACGGCTGCGTGCAAGTCAATTTTTTCTAAAACTACAGGATTGCTATTATCTAAGCAAGCATCCCGAAAAAAGTTATCCAGTTCCGCTAGTTGCAAAGCTTCCATCACTTGCAGAGCTTGTTTAAGGTTGCTTTGATTATCTTTTTGCAACAACAAGCTGACGTAATCTCGATAAATCGGTTCAACACTTTCTTTAAAATTAAACTGTACATCCCTGTTAATTGCCACTAAATCACTACGTAGTGATTGCAAGTTATTAAAAGCAATCTCATAAGCAGGGATGGCGCTATTACTATCTCCTTGTTCTTTAGCAATTGCCCCCACCTGTCCCGCCGCACGAGCTACTAAATCTGGAGCATTTATTTCTTGAGCTATTGTTAGTGCTTGTTGTGTCAAAGTTGCCGCATCTGCCAACTGGTTATTTTCTTGGTAGAGTTTACCTAGTTGGTTAAGTGAATAAGCTTCGGCTCTCGGATCTTTGATTTCTTTAGCTTGTTGAATAGCTGTTGCTAGCAAGTGGGAAATTTTAACGGCGTTGGTGTCCAAAAGTGCTTTTATACCTTCTCCTGCTGGCTTTAAATCCATCAAACTTTCTGCAAAGTTAATCTTGGCGTAAATAGCCGGACGACTAGGAGGAAGTTGAGCAAGATTAGTTTCTATTTCTGGAATTAATGCTTGTGCTGATTCCCCGTTTTGTACTTTAACTAACAAGCTTAATTGATTTAATTGTGCTTCTAATTTAGCCTGTGCTTCTGAAGCTAAATTAACTGCTTGTTGGTAGTATGTCCAAGCAACATCATATTCTTCTAAGTCTCTGGCAATATTGCCAATACTAAATAAAACTGCACTCACATCAGTTGGAGAGTTAAATTGTTTACTAATTTGCCAACTTTTATCGAGAATTATTTTAGATTGTTTTAAATCACCAACAGTTTGCAAAGCAATGCCTAAACTTCTCAATCCTTGAGCCTTTAAAAGACTGTCAGGTTGATTTTGCAATTCTGTCACAAGTTCTTCTAACAAAGTTTTGGCGCGGCGATATTGTCCAAGTGTTTGCAAACCTTGCGCCTGATTAATTTGACTGATGAGTTTACCTGTTTTATCACCTGTGCGCTCATAAGTGACTGCTGCTTGTTTCCAAGTATCTATAGCTGTATCAGTTTGTCCTTGCAGAAGTTGAAGAGTTCCTTGTGTATTTAATGCCTGTGCTAATAGTAAAGTACTTTTAGTATCGGGATTTTTGAAGTTTTTTATAATATTAATACTTTCAACGATCGCAGTATGTGCTTGGGGAATTTTGCCTAAATCTTTATATGCCAATCCTAAATAATTAAGCACTTGAACTTGGCTAATAGTTTCGTTTTGTGATTGATAAAACTTTAGTGCATTTTCCCAGACTCTAGCTGCTTCTGTGTATTGTCCAGATTGATAGTATTTTTTTCCTTGCTGTAATAATTCTGAAGAGTTTGGTCGTTGTTTCACTACCTGCTCTGAACCTAATAATATAGGTTCATTAGCAACAGCAGGAATGTTCTTGATGATTAATAAAAAACTTAATATTATACAAGCAAAAAAAAGCCATAAAACATTATTTTTCTGGTTTGAAAATAACCAAAATCGTTTTTTGTTTAAATTATTGTACCTCTTTGCCCTGGATAGTTTTTTCAAATTAATCCTATTTTTTACATAAAATAATCTATTTAGTTATCTTACAAGGATAAATTATTAATTTTTGAAAGTTTATAAATCGCTACAATTAGGATGCTTTTGAGATAAACTCTCTTGAGGTAAAGATGCTATTAATTCTATTTGTCCTTGGGCATTAATTCTCAAGCTTGTGGCTTCGACAATTTGTTGTCTTATTGGAGTAATTGTAGAAGAACTATTTACTTGATTACTGTTTTGTGTTTGTGCAGTTATAAAATCTCGCGTATCTGACAATATAGTTTGACCACGAATGGTTGCTGTAGGGTCTGCTGGTAAACCTCCCCTACCTGTCACAGTAAAAGAATTACCTTCTGTGGATGCACAACTAGGAGTAACTATTTTATTATTGCGATCGCTCTCTGGGTTTGGTACTCCTATCAAAGCCGAACTTGGAGCTGCATTCGGTTTATTAATTGATTCAAGGCTAGAAAAATCTAACACAGGATTAGGAATTTCCGGTGGAGGACTAAGAACTTCTGGTGGAGGATTGGGAACTTCCGGTGGAGGATTAGGAATTTCCGGTGGAGGACTAGGAACTTCTGGTGGAGGACTAGGAACTTCTGGTGGAGGACTAGGAACTTCTGGTGGAAGATTGGGAACTTCTACTTTTTTGGCGCTAGAAGTAATATTACTGAAAGGGGTGAGTGTATCAGCAAACCCGATTCCTTGAATCTCTCTGGTAGTAATATTAATATTGCCACCACTACCTAAGAATGCATTGGCTGTAATATCACTGTTTTCTTCGGGAACAGCAAACAGTAAATCTGTGTTGATAGTGATGTTAGCACCATTTCCACCTGTAGTTTCATTACCTGCGATCGCCAAAATACTACTTCCACGGCGTAATGATAACGAATCTGTTAACTGGAGATTAATATTACCGCCTTCAGTGCTGACTGTTTTTGTGGAAATTAGAGCTTGATTATCAAGGGTTAATTGGTTTCCTTGGATCTCAATGTTGCCACCAATCCCACTACCTTGGCTAATGGTGGAAATAGCAGCACCATCCCGAATCTCAACTTGTTGGGAATCGACAAAGATATTACCGTTGTTACCGCTAGAACCCAAACTTGTATTAGCAAATAAACCCGTATTTGCACCAGACAAGAGAACTCTGTTTGTAGCTTTGACTACTATATTACCAACATTTCCTAAACCTTCTGTTCGAGAAAATATCTGACTATTATTAGTAGCAACAAAGGAGCTAGTATTAATTTCTATATCACCAGCTTTCCCTGCACCTATACTCTGGCTTCCTATATTTGAGTTATTTAATAAAATTGAATTAGCATTAATAATGATATTGCTAGCATTACGACGATTACTTATGGTGAATAATTTAGCTTGGTTAGCTTCTAAAGAATTAGTAGTAATGATCAGCTTTCCATCTGTCCTTGTTATACTTCTACCCAAAGAAATCAATGGTGCGTTTAGCGTTACATCACCGCCTTGTCCAGCACCAAAGGAAAAACTACCAATAAATGACTCTCTAAGTGGAGCTTGTTCTTGAATAATTGCAGATTTACTGTTGAGAGTAATGTTACCTCCATCTGTACCAAAAGAAATAATTCGTGATGATGGTGGCATGACAATATCATCCTGAGCTAAAAGTGTGATATCTCCACCAGGTTTTAAGAATGGAAATGTAGAATAATCAATTCCCAAACTCGTCAGAAATTGGGGAGTAATAATTTTCCCCCGTGAATCAATGATAATGTTTCCTGTCTTTGCACCCCTACCAAATGTGCTTAGTGCAAAGTTAACTCTAATATCACCCGATAGAGAAGAATTAGGTTGATACTGATTGGTTAAAAAAACCAGTCCTCCCGAATTGATAATTTGATTGATAGTGATATCTGCGCTTGTTGGTTTACCATCTGTGCTAGGAGTAGGTGAAAAAGCATTGATTACTCCTTTGATTCCAGTTGGCTGAAAATTAGTAGTTCCCGCTCTAATATCAACAGTAGGTTGAGCGCTGCCATTAATGATAACCTGCGTTAATCCATCGGAAAGAGTAACTGTTTCGTTAATAAAGTTAGTTGTATCAGGACGGTTCACGTTAATATTATTGATTCTTACACTTCCACCTGCAAAAATATGAATGGAATCTCCTGTATAACTATTAAAATTAACATCTCCACTTGAACGAATAATTGGGTCGTTAAAGCTAAATAAATCTCCTTCTTGCCCGTTAATTTGTTCGAGGTTAAAATTACCACCACTAAAAAATTGAGTGTCCCCACTAATCGCATTGGCTGAACGGAAAACCATATTTCCACCAGAAAAGAAGCCACTGGAGGGATCATTTAAGGCAAAGATATCTATCTTATTTCCTTCAGCTAACAGTTGCTGTTTAGCTGAGGCAATGAAAGGGTAATTTAGGTTGTCCCGCACTTTTAGAGTATTACTAGCTTGCAAGGTTAAATTACTACCTGCTTGCAATTGCCCTTGTAAGTCAATATTTGTACCAACTAAAGTCAAGTTTTGTCCAACTGATAAATTACCACTGTTAGCGATCGCACCTTGGGGCGCTAACCAACTTTCTAACCCCGGAGGAACATTGACAGTTAACAAGGGGGGTGCTTTAGGATCTTGAGTAGTAAATTGATAACCGTTTTTGAACAAAAGAGCGTTGCTGGTGCTAGCAAAGAAAGAACCAGAGATATCCAAACGCGCATTTGTACCGAAAATTATGCCGTTAGGATTAATTAAGTAAAGATTGGCATTTCCTAATACTCCGAGTCTACCGAAAATATTAGAAGCGTGGTTTCCTGTAACTCGACTCAGGATATTTTCGACTCCAGAAGGATTAGAAAAGTAAACCCGTTGCTGATTACCTACATTAAAATCTTGAAAACTGTGGAATAGGTTACTACCTCGAATTGCTCCGCCATCTATGCGATCAATGTTACCTTTGGTACTTTGAACATTAGGTGAAAGAACAGAGCGTTCGACTCCCAAACTTTCATCAGCAGCTATTTGAGCTACAGCAGTTGTTGTTGAACTCAGAATACAGGCGATCGCAGCACTGCTTGTTAAAATTTTCATCAGCATAGTAGCCCTATCAGTTTTCTCTGTTTCAGTAACACCTGAATTCTTCTTCCACTTAAGGTCAATAATTTTTAACTTTAATTAATTTATGTTTGGGTAGATATACACATCCCAGCCCATTCATACCTAAAATTCCGATCGCCGGACTAGGTTCGGGAACACTGGTAGACACAACAGATGTTACTAAATTGACATTGATAAAAGTATTTGTATCGTATGACAATCCTTGCAAATTAACCGAGTACCGTGGGTTTAAATCCCCAGACTCTCGTTCGCTCTTGGCGTGCCGTAGGCAAGACTCGCTAATGCTTCGCTATCACAAAACTTAATTACGAATTATTTAACACTGTATCACCAATCAATGAACTTGCTGCTGCTACTTCAAGTTTCATTCCAGCAGTTATAGTAATATCCGCAGATATCACTATGGTCAGAAATTTACTAAGTAAAGCTATTTTTTACCTAAAATTAAAGATTTTTGTAGGTAAATCTGATTATCCTTCACTTTAGTTAAAAATAGCATTATTAATAGAAAATTTATATAATTCTCCTTACTTCTTCATGAAAACTTTAATTTAATTGGTTTGATGTTGTGATTTATATGCGTAAAGAAACTGTTTGAACTTAAAAATTCTCCCTTTTTTAGGACTTTTTATTAAAAAAATCAAGATAATTAAGTGATATAATCATCAGCCGAGCGAATCATATTATCGCTACAACAACTTTAGTTACAATATTTAATTTTATTTGTGTCAAATTTAGGAGTACGATTAGTTTGGTTTAAGACCTTGGATAAACTACACAGGCAGGGTGCTTCTTTGATTTTCTATAGCAACAATATTATTGTATCAGCAATTACAGAAAATAAATATTGCATGGCAAATAGTGAAAGCTTTGCTAACAGCTTCAGCGAAAATAATTCATAGGTATTTATAAAAATATTACAATTATGAAATTGAATTTTACGAAACACATTGAAGATATCCAATTACTGCATGTAGAACGATATCTCCCAGAAAAGATAAGAACTTACATTGAAGAAAATTACTATGCCAAAGTTCAGCAGCAAGCAGAGTTAGATTATGCTGTTAGAGATGAAAATTTTCTAGCAAATCCCCTTCAGCACGTCGCACTTTATTCGGATCATGGTGTCGTTCATGTCAGAGATGTTGCTTGTAATATCTTAGTTGTGCTGGAAGCTATTCATGGAGTTCTCATTCCCAAAAGAGAGTCTCTATGGTTTGATTTTATGAAAGGTTATGGAATCATACTTGTCTATAACCATGATATGGGAATGCTTGATTTTTCGCCATTTGGCCGGGCGATGCACCCAGAATTTGTTACTCAAGAAGTATTTAGTTCTGCTTTTGATCAGGTAATTGATACGATTTGGACTGAAAATTGTGGCAATGTTTCTTGGCGTTTAATTAACTTAGCTGATAAAGGAGCATTGACAGAAGATCCTCAACTTGTGTTACGTGAAATGGTATCATTGGGAGTTGCTCATAGTAAAAGCAAAGTTCCTATTGAGGTATTGAATAATCCTCAACAATTCAGAGAGTTAATGAGAGAAATTGCTTCGGTTAATTTGTATCACCTTTATTACCAACAACAAATAACTAAAGCCGAAAATCAATTATCTCATGCGAAAAAATCTTTCCAACAACAGCTTAAAATTGAAAAACTAGAAGTAGCTTTACAGCAAATTAAAGCTACTCAGACAGAATTTCTTAAACAGGGAATTAGCCCTCATAACGAACGTATTCATAGATATTATACTGACTTTGAAAAACAGGCATTTTCCTGGCTGGTTTGTGAGCATCCAGAGGTACAAGCTTTAATTGCTGATGTGGGTGATACTATCCGTGCTTTGCGGGCAGCAGATGCTTTGCGACAGAGAGGTACAGTTTACAAAACATCAGGAGGTTATCAGATTTTTGTTGACCAAAATACAGCTAAGGCGATTTATGCTTTGCAAAAAGGCAGTGGTGAATTATTTTTATTAGAAGCAGCAAACCCTCTCAATGCTGGAGAAGCAAACATTGCCAGTAGTGAATTGACTGCTAACGGCGATATCAGAATATCTTTCAATCGAGGTTCATTTACTAACCAAGATGCTACACAACGAGCAGCTTACTATTTAGCTATTGTAATTGACGATATTCAACGCGATATTATCGATACCTTTCATCGATCGCCTGATGACAATGATGTAATTAAGAAAAGTGAAAATATTGAAATTTTATTAGAAAATACTGATGACAACCTAGATTTTGCCGAAGCTGTCCAAGCAGAATTAAAAAAAATCGCGCCAGAAATAGGGTTGAAGAGTAGAGTTGTTCCCTCACTCAAAAATATTGACCCAGAGGAACGCGATCGCTATTTGAGTGCCAAAGAGCTAGATTGGTCACTGGAACAAAAACAAAAAATTCTATTGAGAGTTTCTCAATCGGGCCATAAAATTCACAATATTGATCCACACAAAGCTTTTACTGATGTGTACTTATCCAGCCTTGAAGCAGGTGAAACATTGATCCAAGCAGGATCGCCTCCTGGTTTTGTTTATATTCCTATGGGTATAGGACTCGTAAGTAACCCATTAGGCGGGTATCAACCCCAATGTGTAAAACCTTGGATTCCGTTAGGTAATATCCGGGTTATTCGTGGAGATCAGCAGGAAGCAACTATTACGGCTGAAGAGAAACTTGAACTTCTCATCATTCCTAAAGAGACTTACCTGAAATATTGGCACAACACTTATAATGCAGAAGAATTTTCGCAACAAATCGTGCGTATTTACGCCGAAGATAATTTGCGAGAGTTAGAGCAGATTTTTAACATTCTCCGCCAAGTTGCCCTGATTGATAAAAATCTGGATGACACTGAAGTTGACTTCATTCAACAAATGCTGGATTCTTACCGAATTAAGTATTCCACTGAAGAACTTCGAGAAAAGTTGTTAACTGGTGAAGATAGCGATTTTGTTAGTTTACGGCAAAGCGTACTAGATTATCTCTCGTTAGAGCCACCATATTTTCAGGTGGGAAGGCTACGAGATTTATTAAATTTACTAGTAAAAATTGACGAAAATATTTCAGCAGAAGAATCGCTGATTATGTCAGAGTTAAATAATTTACTGGATAGTTATCTAGCAGATGAAACCTTGCCAAAGCAGTACAAGATATTGATTATTCCCACTAATTCTGAGCAAAATGAAGGGATTAGAGCAATATTTCCCACTGCCCCCAAAGTTGAAAATCCTTGGGGAAAAGCTTATCTATGCGGTTCGTTTTACTCGAAAGAATACGCCAATATGATTTTGCAGAGATATCGCAATTTGAATTTCTACGCCATTCTAGAAGAAGAGGAATATTCAGCATGACAATCCTTCAAAATCAGCCCATACCAGTGATTATAGATACGGATGGTGGTGTTGATGATGCCTTGGCATTGATTATGGCATTGAACTCACCACAATTAGACCTGAAAGCAATTACAGTTTTAGCTGGTAATATTCATGTAGATCAAGCTGCAAATAATGTATTACGGGTACTAAGTATTGTTGCACCCAATACCTTACCAATTGTTGCTAAAGGCTGTGAAAAACCTCTGGTTAAACCGCCCTTTAATGCTGCGGGGATTCATGGTGCAGATGGGCTAGGCGAATTAGATCAATTTAAAGCCGCAGATGGTACAGCCAGCTATCCGCAATTAACCATCGAACCATCTACAGAAAATGCTATTGATGTCATTCTCTCAGCAGCCAAAGAGTACGGCGATCGCCTCAATATTATTGCTTTAGGCCCACTAACGAATCTAGCAACGGCAATTCAAAAAGATGCCGCAACTATGAAACAAATAGGGCGGATTATCATCATGGGTGGGGCTGTCACCGTACCTGGAAATATTACGGCGGCGGCTGAATTTAACTTTTTTGTAGATCCTCATGCTGCTCAAATCGTCATGGAGTCAGGGATTCCTTTAACATTGGTGGGTTTAGATGTAGCCATGAAAGCCCCTCTCACCCGCCAACTTGTGGAAGAAAATTTACAGCGTCGTCCTACGAAAGTTACCCAGTTTATTGCTGATTGTACCGGAATTTATATGGCTTTCTATCGTGATCATGAAGGTTTTCACGGCTGTTATTTACACGATCCTTTGGCAATGGCAGTTGCTATTGATCCGAGTTTAGTTACTACTGAATCACTTTATATGGTTGTGGAAACTGAAGGACGATTTACCACTGGTTTGTCGCTAGCAGATAGGCGCGATCGCCGAGATGATAAAAGCCATCCACCTAATGTAGAAGCCTGCTTAGATGTTGATACTAAAAGGTTTTTAAAGTTGTTTGATAAACTTGTCTGTTCATAAAGATATAAAAATATCGCTCGTTAATCATTAAATAATAATTCCAAAATAGCCAATTTCCCGATCTAATATCATTAATTGCCAAATGGTTGAGCAAAATTTCTTAAATACATCAAATAACGAAACATTACCGCTTCATGAACTGATGGCAAGAATTTTAGTTGCAGAGGAAACTTCCTCTCGGCAAATCTTACCTTTCATGGGAACCATGCAATGGCTTAACGATTACCTTACCCCTCAATCCTTTGCGGATTTTGTCAATGCAATTCTTCGGGGTATTGGACAAGCAATTTTTGTTAATAATCCACTGAGTGGGCTATTAATTTTGGTTGCTATTTTGCTACAATCCCCTTGGATGGGACTAATGGCACTACTAGGCGTTATCGCTTCAACCTTAACGGCGATCGCCTTAAAAATCAACCCTGATGTTATTCGTAACGGGATCTTTGGCTTTCAAGGAACTCTGGTGGGTTTAGCTCTGGCAACCTTTGGCTCATTGGCTAATGGGAATGGGGCATGGAATCCTTTATGGGCGATCGCTGTAATTATTTTAGCAGCCCTCACCACAGTATTAATGAATACCTTCGGGGTATGGTTTACCACTCATTTCAAAGTATCTATTCTGGGTATTCCCTTTCACATTGTTACCCAAGTTTTTTTATATCTAGTATTACTGATTCCTCAGCCCTACTTTCATTGGGGATTTGGCATCTTTTCTGTTTCTGCATCGGCATCTAGAACATTAGATTGGTTGAAGATTTTAGCATCTTTTCCTATTAGTTTTAGTCAAGTTTTCTTCGTTTCAAATCTGAATTTAGCTATCTTAGTTTTCCTAGCTGTAGCACTCTGTACACCCATCGGCGCAGGCGTTGGTTTACTAGGCTGTTTAGCTAGCGCGATCGCCGCTTTAGTTATGGGAATTGACCCAGAAAAAATTTACACTGGGTTTTGGGGATTTAACTCTGTACTGACAGCGATCGCCATTGGAGGAATGTTTTATGCACCTAATTTTCGTAGTATCCTCATTGCCGGATTTTCGGTGTTGATCTGCACTCTTTGTACCCAACTACTAGGTCTTATATTCAATCCTTTGGGAATACCATTTTTAGCATTACCGTTTTGTCTAGTAACTATTGGTTGTTTTTTGGTAGTGCAGCATTCTCTCCCTTCTCTTGTTCCTGTCGCTCTTTATACTATTACTAGTCCAGAAGAACATCGTCTGCGCTACTTGACAGCCAAGGATGTAATTTCTAACTTTCGTCGGCAGCTAGAATCAGCTATACAAGGAACTCACCATCGTTTTTTGTTTCATACTGCTGATTCATCGCTTAAAGGCAATCTGCGTTATATCTTTGATGCCATCGATCAGGATCATAACGGGACACTATCAGTTCAAGAGTTCGTTACCCATTTACATAAAGCCAATGCAACCATATCTGAAGCAGAATTAGCGTATCTTTTTTCTAGAATGGATATTGACAACAGTGGTGAGATTGATTTTGAAGAATTTGGTGAACTCATGTTGCGACATCGCCGTTTGATGTCAAAGTATCAAGAATTTATCACCTATTTTCTGCCTATTGATACTGATGAAGATGAGTCTATCAGTATTGAAGAAATGAATGTTGCCTTATCCAGTGTTGGTGAATGCCCATTATCACAAGATGAGATAATTTTTTTACAAACAAAAACTGGAGGAAACCCTTTGAGTTGGCATCAGTTTATTGAAGTATTACTTCTGTGCTAATCGATACTGTGATTTCTGTTCTAGTTCCGCAGTTAAGAGTCACAAGAAAGACAATTACTAGATTTATCGCTTTCTCGTTTTGTGGAGAAAGGACTGCTAAAATCTCCAAAACAACAACGTACTCCCTCCGCCAAAGACTCAAATTTAGCGTTGGGGTTGTAGTCGAAAGTACCATCAGGCTTGAGAGTCAGTAGAGCGCCAGAAGCTAAGGCAATAGCTGTGAACCTATCCCACTAATATAAAAATGTGGTAATCTACTTCTCATTTGAGAAGGGTGTATCACTGTATGGCTGGACGTTTTGAAGGACTGAGTGACCTAGAGTGGAAGTTGTTTGAAGATATATTTTCTGAGGAGGCATCTAAACGTGGCAAAGGAATGCCTCATGCACCATATCGTCATGTATTAAATAGTTTGTTGTATATCCTGATTACTGGGTGTCGATGGTGTGACCTACCACGTGGTGATATGTGGGCATCAAAAAGCTCGTCTCACCGATGGTTAAAGCGATGGCGCTCAGATGGAACATTTGCATATTTACAAGCACGTATATTAGCGATGCCTGCGGCGGGCTACGCCTACGCTGATGAGAAAGGTCTTATCAACTGGGATTTTGGAGCTGTTGATGGCTCTTTTTCCCCGCTTGTTGGGAGGAGGTGAGGAAATTGCTTATGGTGGCAAGGGTAAAGGTGTTCTTATTCACACACTGACTGAAGGTAATGGAATGCCCCTAGCTAACTCTACCACTCCCGCCAATGGTAACGAAAGAGAACAAGTCTTACCTCTACTTGACAAAGTAAAACTGAGAACTTTGAAACGGGGTAGACCACGTAAAAAACTTAAGGTACTGGCTACTGATAAAGGTTATGATTCAAAGGAAAAACGTGCTGCCCTACGTAAGCGAGGCATTCGACCCCAAATACCAAAACGGGTTTGGAAAACCAAGAAAAATAGAGGTAGACCTATTAAAATCTCTGTTCCCAGATATCAACAAGAACGTTGTTTTGCTTGGTATCAACGTAAATATCGTCGCCTAGTTGTTCGTTGGGAACGTAAAAAAGTATATTTTGATGCATTCATTGACCTTGCTACTATTCATATCTGGATTCAAAGAATTTTATTAGTGGGATAGGTTCAAGTATTATCCAATACTAATTACATAAGAAATAATTATCATGTTTTGCAGTAGTTCAAAATATGAAATGATCAAAGTAATGTGTCGTATATTGGCTGAGGAAATTGACTGTTTCATCTCATCGAATTGCCAAGAGGAGCGAGTCTACAGAAGAACCGATTTTAACAGACTCAAAAACCCTTAATGAAGTTATTGAGTGTTTAGTAGAAAATTTTTCGATTGAAACTCAAGGAAGATGTGACCAAAAAACTTTATTCGAGATTCTCATAAAAGCAGCTAGCAGTGGAGATAGATTGAGAACACAGCTAAACTATTAAAGAATGTTCCTACAGCCAATGATATTAGATATCATCTCAATAAAATCAATAATTTTGAAGAATTAGAGGCGCAAATAAATCAATCACTGAAAAGCCGAATCCCTTTAGGATTAAAAAATGGTTGTTTAAAAATAGCGATTGATTTAAATCTAATTTGCTATTATGGTAAGCCAACATTAGAGGAATTACCTTACATATATCGAAGTCAAGCTAAATCTGGTACTCATTCATTTTACGCTTATGCAACTTTATATGTTATTACCAAGAATAAGCGTGTAACTCTTGCAGTTAGAGGGGTTCGTAAACTAGATACCAGTGTAGCACTCATTACTTATTTATTGGCAGAACTTGAATCCCTTAAAATAAATGTAAAAAAACTCTATTTGGATAGAGGATTTTTTAATACTCCTGTAATTAGATGGTTGCAGGCATTAGATATTCCATTTATGATGCCTGCTGTCAAGACAGGAAAGAAAGGAGGAATTAAGCAATTTTTCAAGGGTAAAAAAAGTTATAAAACTACCTATAAAATTACAAGAGATGAAGATGATTCAGTCACATTTGACTTATGGATTGTCTGCAAAAATGGAAAAGGTAAGCGTAAAAAACATGGGGTTCAATACTTTGCTTACGTGACTTACAAAATCACAACAAATTTAGATTATATCTATCAAGATTATCGGAAACGATTTGGAATTGAAACTAGCTACCGTCTGAAAAATATTTGTCGAATTAAAACGAATAATAAAAATCCATTTTTGAGATTACTATTCGTGGGTATATCTTTTCTTTTAGTTAATATTTGGGTAAATCTTCTTTGGCTCAGAATCAGTCGTAAAAGGAAAGGTAGTCGATTAATTTATCGCACACTTTTTACACTTAAACAGATATTAGCCTTTTTATCTCAAGCCCTACAGCGTAAATATCAAGTAGTTGAAAGCATCTATCTTCCATCAGGTTAGTAATGATAATTTCTCTACCAACTAATCATAAGTAATGATAATCTATACTATGTCTGTTGGTTAGAGAATTGTGTATCAAAATGTATTAAAAAATGCAAGTATTTTAGCGATCGCTCTTTGGAGAAAAACTTTTTGGTTTACTGATAACTCTACTACATCAGCCCTGTCTCTTCATCCTCTTATTTTGGCTAAGGTATTGTTAGGAGAGGGATAATATTGTTAATCTCTAATTCCATTTGATTTGCGTTCTCGTCATATCGCTTTTAGTCTAAACTCCAGTACCTAATTGTTGAGTGCGACTCAAAGCAGCAAGCACTGCATTAGAGATGAGAGTTCGCATACCACCTTTTTCTAACTCGTAAAGGCCAACAGCAGTCACTCCCCCAGGACTCGTTACCTTGTTTCGTAAGACTGCTGGATGTTCATCAGTCTGAAACATCAGTTCTACACTGCCAGCAATCGTATGCAATGTTAGTTCTTGGGCTTGTGTCCGAGTTAAACCCATCTGAACCCCAGCATCAATCATCGCCTCTATGTACAGAAATATAAATCCAGTCCCTGCGCTACTCAACGCCGTTGCCATATCAAGGTAATGTTCATTTTGGGTAGGAAATTCCTTACCTAATGCTTGTAAAATGACTTGAGTATGCGATCGCTGTATTTCTGTCACACTTGATGATGCACTCCAAACCGTAGTCCCATGCCCAACTTGTACTGCTATATTCGGCATTGTACGGACAACAGCAGGATGATTCAACCCTTCGCACAGATATGGAATACTCGCTCCACTCACAATACTAATTACTAAAGCATCAGGTGAAATTTTACCCTTAAGTATAGCCAGAACCTCTGCTAAAACCTGCGGTTTCACCGCCAATATCACAATAGACGCGCCAACAACCGCTTCTATATTGCAGGTTGTAGTACTTACTCCATATTCACTTTCTAAATGAAGGCATCGCGCAGAAACTGGATCGCTGACTATAATTAGATCGGGTTTTGGAACAATTTTAGTTGATAACAATCTAGCCATTATCATTTCGCCCATCGTGCCACCACCGATAAAGGCAATTTGTAAATCTTCGAGCATCTCTTCTCCCTATTATCTAAGTTATTTGATATATTGGCATCAAGATAGATTAGGTTGAATCACAGCTTTTAATACAGAGCCTTGCTCTACATCTGCCAGCGCTTGATTAATTTGTTGTAGTGTATATGAACGACTAATTATGCTTGACCAAGCAATATTTTTACTGGAATCGCTATGACGTTTTAGTAATTCAATCATTCTATAAAAATGGCTGAAATCAATTCCCCAAGTCCCGCGAATATCAATATGTTTTAGATTAATTTCCAGGTGAGGATTGATGAGTATTTCACCCGTATTTGTGTAATGCCCGACAATAACATAGCGGCCTCCATTTCTGGTCATATTCAAGCCCTCTTTGACAGCAATGGGAATGCCTGTAGCTTCAATAGTGACATCAGCACCGTGTCCGTTTGTCAATTCCAAAACTCGCTCAATATGTTGTCGTGGATCATCAGCCTTAATTGCAAGGGTTTCATCTACACCGAAGGATTTTGCAACTACTAATCGGCTCTCAAATTTATCAATTACAATTACTTTGCCTGCACCTGAGAGCAAAGCTAGAATTGCCACACTCAAACCAACAGGCCCACAACCCTGAACCACGACAACATCACCAATTTGAATCTGCGCTCGGTCGATAGCGTGTAATGCAGTTGGTAAAGCACATCCTCCAGCAATGAATTGCTTTGGTGAGACTTCTTCGGGTAGAGTTAGAACTTTAACCCCTGGTTTGAGGTAAATCAGTTCAGACCAACCACCCAGCAACCCATCTTTGGCTGAGTAGGTGACACCATAAACTTTACGTTTTGGACAGCGAGTGGATGCTTTGGCTACTAGACAATACCAGCAGTTGTAACAGGTTTCATGGACATCTAAAAAAGTAGCGATCGCTCCAGGCTGAATTAATTTACCATTGACATCACTAACTGCTCCACCTGTTTCCACCACACGACCAACTGAGAAGTGTCCAGGGATGATGGGATACGGTACTCCCTCTAAACGCCCATGTAATAAATGTACGTCAGTTCCACAAACCTCAGAATATAAGGTTTCAAGAATAATTCCACCCTTTTCCAGAACCGGGTCTGGTAATTGTTGGACTTCAACTGGTTGATTAGGTGCAGTCATCACAGCTGCTAAGGGCATGAATTATTTCCTCACTATATTTACCAAATTGCTTCTTGCTGCTCATATTCAAGACCACAAAATGATTTCACCGTTAGGAAGTAATCCGATCGCAGAGGTGAAAGTCACACGTTGTCCATCCATCGGCTCAACAGTGTGAAAGTTGCGTGTATTGAAAATGAACACATCTCCTACATAAGGTTGGAAGGCGATCGCGTCTGCATCTGCAATTACTGTATCACCATAGCCGTAGGAATCGAGTTTATATTGCTCATCTCCTGATTTCCACTGGCGATCATAGATGCGTGTTTGACCATGATTGTTTGGAGAAAATTTCAAGTACAAATTCCAAGAAAGTTGATAAATAACTGTACCAATTTCCCATTTTGATTGTTCTAACGGAGCATAATCAATATGAAGTTGAGTACCCTGCTCTATTTTTCTGATCAGTCCTGCATAATAACTACCATAGAGTGGTTCCGAAGCAATTCGTACAGTCGCGCCTGTACACTCTCGAATTTTCACCATTAAGCGTTCTAATGGATTAAAAGAGGCTGCCATAATGCAGTCTCTTAATTTAGTTGTGCGTTCAACTGCTTGAAAATAAGCTGCTTTACTAATGCGATTATATTCAAACACTGTGATACCAATTTTCTCAATCTTGGGATTCACATTCTGATAGCAATCAAAGTTGAATAATTCAGCTTGATTGACTAACATCTCACACTCTTGGGGTGTAGCAAATTCTTTTAGCCGAATTAAAGGAATTCGGTTTTCCCACAGCATTCTTAAAGACTCTATAGTTAAGGGATACTCTTGCTTATTGTCCCAAACTTTGGATTTAATCTGGTTAGAAGTAGCAGCCATAATACAATTCCTTACATTTAAATTTCAACTTCAGCTTTAGTCAAACTCAATTCATATTCAGCAACGCTATATTTGCTTGTGATGAGTGCAAACTTGATTATTTACTGTTTACTAAAATACAGTCTTCGTACCCTGTCACAACAACGATATAAACCGATAACTCGACCTTCTCGATCTCGCACCAATTCAAACTTATCTACATATATAAGATATCTAAGAAAAACATTTTGTCCAGCAACTATGAGATGAGATGGTGCATAGCCTTTGCTCTTATAATATAATTTATTACCTACTAGATTTATTTTAAAGTCGCGCTCTAATTCAGCAGAATAATAAGTACCAGGATAATCTGCTAATATATCTTTTGGAGAATCTAGTATTTTTTCAAAAGTGTAGGTTTTAATACCATCACCAATATCTAATTTTCCTATCAGGTGAATAATATCTTCAGAAAACTCAATATCATAGTCAATTTCATTATCGACAGATTGAAAATGATTTGTGTCAATTGGAATAAGTTGAAAATACATCCACGCTAGTTTAGCCATTAATTTTCCATTTTTTATCTCTAACTCCAATATGCTTCCAGTCGTGGGGTTATGATAAAATCCAGCTTTAAGTTGTAGCTCCACTACAGGTAAATTAATAGAGCTAATAGAACGCGAAATAGGTTTAGTAATATTTTCAATATAATCATTTTCTAAATATATATCAGCAACTTGAAAAGCTAATTTAGTCGGCTTAAGTGTACTTAAATTAGCCAGACAGATAACAGAAAACTGGCGTTCGGGAAATCGAATAAAATCACTCCGATAACCCGTCCAAGAGCCTCCATGACTAATTGTTTTTAAGCCGCCGCGATCGCCAATCTGCAACCCAAATGCACCTGATATAATTTCGCCATTATTGAGTTGGCGTGGAGTAGTTATCTCTTCAATTAAATCTTGTCCGTATCCACCTAAGATATTGTGATAGAAATTTCGATCCCAAAGTAGTAAATCTTCGATAGTTGTATAAAGCTGTCCATCTCCACAGAAATCGTGAAAAGACATATCGATCTGAAAACCCTCTCCATCTTTTGGAGCGTATCCATCGGCTCTATTTTTCACGATTTCTCTAAAGTTATCGTGAAAATGGGTATTTTTCATTCCTAGCGGGGCAAAAATATGTTCTTGGGCAAATACACGTAAAGATTTGCCAGAGACGCGTCTCACAATTTCTGCTAGTAAAATGTAGCCAGAATTACAGTATAATTGCTCAGTTCCAGGCTCGAAATTTAAGCTTTGTTGTCGAGCAATTAAGGCAATAATTTCTTCGTTTGAATACTTATTTTCAAACCTCATTCCAGCAAATAACATTAAATGTAAATAGTCACGTAAACCACTGGTGTGGTCGATTAAATAGCGGATAGTAATAGAATGACTATATTGAGGAATTTCTGGAATATATTTTTGTAACTCATCATCTAAGTTAAGCAATTTTTGTCTGGCTAGTAAGACGATACACATTGCTGTAAATTGCTTGGAGTTGGAAGCGATATCAAATACAGAATTAGAGGTTATGGGAATGTTGTATTCCAAGTTAGCCATACCATAACCGCGTTGGTAAATTATCTCCTCATTCTGAATAACAGCAATAGCACAGCCAGGGGAATTAGGTTTATTCCACCGGATGAATAATTCATCGACTTTGGTAATTAGCACCATGATTTCTTTCTGATTGATATATTTCCATCTCACAATATCTTCTACATCACACCGCTACTTTTACCTTTTATAGGAAAAAAGTAAATTACCTTCAGCCGCTAAACTCTCACCCATTTCAATATTTTTGGATCTTTATCATATCCATAGGTAATGCCATCCCTAGTAGTGATAAACTCCCCTTTGCTTGCCTTACTTCTAATAGTGGAAACAGAATAGTAGGTTAATTCATTCATTTCCTTATGACTTAGCTTTTTAGTTGTGCTGCTCTCTGAATCATTTAGGGACTTATCTTGAGATGAATCATCTATTTTTATTTGGACATTTGCGGTGGATTTAGTAATACTTACTTTTTGACCTTTCTGCTCCCGGTAATCTTGTACTCTCATAAGTTGCCAACTGGAATCTTCTGTAAGTTCCAGAACCCATTGATGATAATCAAATAGACTTTCTCGATGCCCAACACTAATAAACGTTGTTTTCGTATCTTGTAACTGTTGGTATAAACCTCCTTCATTTTTTAAATCCAAGGCACTTGTTGCTTCATCTAATATCGTAAACCTTGGATGGGTAACTAATAATCGTGCGAAAGCCAGACGTTGTTGTTCTCCTAGCGATAGTATGTTCTCCCAAGGAACTTCTGTATCGAAGCTATCGACTCGACTTAGCAAGTTTTGTAGGTTGACTTGTTGCAAAACTTTTGTAAGTTCTGCGTCAGTCATCTGACTATTTGTAGTAGGATAAAGCAACTGTTCGCGCAAGGTTCCTAAAATTATGTAAGGACGTTGGGGTAAAAATAAAACTTCTTCTAATGGAGGTCGTACCAAACGGCCAGTCCCCGCATTCCACAAACCAGCGATCGCTCTCAATAGAGAACTTTTACCTCGACCACTCGGCCCAACAATCAATAAACCTTCTCCTGCTTTGACAGACAGTGATAAATCTTCAACAATTACCTGTTCATAATCGGGCGTTTGTAAGGTGACATTCTCAAAAGCGATCTGATTTTCTTCTATTGTTTTAATGGTAGTTATATGCTCTGGTTCTTTGGTAACAGCTTCTAACGCATCTGAAAATTCGGATAACCGTTCAACATAGCTAGAAAATCTTCCAGAATTCCCAAATTCATTGATTAACTCACCCAAAGCATTAGCGAAAAAATAGCAACATACAGACGCTTGGATAATTTCTCCAAACTCCATTTCACCTCTAATCTGTAAAGGCCCAAATACTATATATGGAAATATTTGAATTACAGATTGATAACCTCTATTAAAAATCTCATTGTTCTTCTCCCAATCAATTTTGCGTTTAGCATTTTTTATCAAATTGCTAAATCGGCGGTTAATAATATTTAATTCTTGGTTCTCTCCTCGGAAGAAAGCTACTGATTCAGCATGAGTGCGGAAATGAGTCAGGCAATAGGTGTACTCAGCTTTCGCTTCGAGTTCTTGTCGATTAATTTTATTTAATTCTTGGGTCAAGTAGACAGCAATAAAATTGCCTATAACCGTATAACTAACTAAAATCAGTGCAACAGACTGAGAGATTGACCAAAGAACTAATAAAAAAGCTGTCATCTCCAGGATTTTTTCTAGGAGAGTAGCTGAAAAACTTAAAGCATTACTTGCAATGGGTTCGATTTCTTGAGATAAGCGTTGATCTGGATTATCAATACTAGATGTAAAGTTAATTTTATAATAAGCTCGACTGTTTAAATATTTTGATAAAATCTGATTATTCAGCCATTGATACCAATCTAAAGCAATTTTTTTTCTCACTAGTCTGGAGAACCCGGCTAAGAGAGTTCCCAATGCTAGAGCTGAACCATAAAGCAGTAAAGCATCATAAAATTTAGAGATTTCCTTCTCTTGAATGATGATATCTGCCAAATAGCGATTAATAAAGCTATTAAAAACATTTGCACCAACAAGGACAATTATTAATAATATTAGGAGAATAAGCATTCCCCATGAGCGAATCACTTCTGAGAATGCTCTATCTCCTGGCTCGTTTGGATACCAGTAAGGTTGTGCGACTGCTTTTACGTCTTTCCAAAATTGAATAAAACCTAAAAAAGCATTTGTTGAAGGTTGAGCTTGAACAACTTGGGTTGGCATATTCTGAGACTAAACTAAGACTTTAGCTAATAATTAAAATAGTTACATGGAAGTTGTGTTAAGGCTCAATTCCTTACTAAATAAGCATTATAGCCATAAATAAAGTAGCAAATTGTCCTAGTGTAATTATTGGGTTTTTTGGAGAAAAATAGGCTTTTTATCACAAATCGGTAAACATGCTTGTGAAGGTATTATTTAGCCCAACTTTTCTACTAACTAACCCATTTATTAATCTGCTGCAAGCTCCTTGGTGTCGAGAGTTGACAGCAGTTAATAAGTTTTCAGCAATGTTTCATATTCTATAACGCAGTATAAACCAATTTACATTTTATTTTTTGTTTTTACCCCCATTTACCGAGCGGATATCTCTTAACTGTCTTAACTGTCTTAACTGTCCGCTTAACTGTCTTAATTGGTATTGTATTTTGTTGACTAAGGTGAGATAATTCATAAGTTCAATTAAAAAGTACAGCTTTAAATAAACAAACTCCGCTTATTTAAAAGTCAACTTTTATTGAAAACTAGTAAAATATATCATTTGAAAAGCAAATTTTTGATACTTATTACTATCAGAAAGTCTAGTTAATATTAACTTTACTCTTAGCTAAGACTGTAAAAATTCAAGATAGCTTTAGAGGAAAATATTAATTCATTAAAATTAGTATCGATTATTAGAGTAGAATCATGAATTTAATAAAGCTTCTAGAAAATCTTTCAGCAAAGAATGTTGAACTTTGGGTTGATGGAGACAAACTGCGCTATCGATCGCCTGAAAACTCCCTAACCCCTGAGTTATTGCGCGAAATTCAGCAATCTGAACTAGAAATTATCCAAATTTTATCCCAGAGTACCGCTCAGGCTGCAACTTATCCCCTCTCTCACGGTCAAAAGGCACTCTGGTTTTTATATCAATTAGCACGCAACAGTACTGCTTACAATGTCACGTATGCAGCAAAATTAGTTATAAGTTTAGATATTCTTGCCCTAAAGCAGGCAGCACAAGCTCTAGTTGAAAGGCATCCACTTTTGAGGACTACCTTTGCAACCATTGACGACGAACCTGTGCAAACAGTTCACGAAAATCAGCAAGTTGACTTTAGCATCCAAGAAGCTTCCGATCTTGGGCAAGATGATATAAACAACTGGCTTTCAGAAAAGAGCGATCGCCCTTTCGACTTAGAGCAAGGCCCGATATTGCGCTTTGATTTATTAATTAACCATATTAAAACTGATAAATTAGCAACCAAAGAACATATTCTCCTAATCACGCTGCATCAGATAGTGGGAGATTTCCGGTCTTTAGAAATCATAATTGGCGAACTGAGAGCTTTGTATAAAGCGATGTCTACGACGGGCTACGCCTACGCCACAGGTGAAACAGCCCAACTATCAACGCAAAATTATCAATATCAAGATTACGTCAAATGCTCAGAGCAAATGCTCGCTAGTTCACATGGAGAAAGTTTGTGGGCTTACTGGCAGCAACAACTATCTGGTGAGTTGCCATTACTAAATTTGCCAACAGATCGACCAAGACCTCAGACCAAAACCTACAATGGTGCTTCCCGCTTTTTTACTGTTGAGAAAGAACTGCGGCAAAAGCTCACAGAATTGGCGACGAGAGAAAGTGCCTCTCTATATATCCTTTTATTAACAGCATTACAAATACTATTACGACGTTATACCAATCAAGAAGATATTTTAATTGGCTCTCCAATGGTGAATCGGAGCCGTTCAGAGTTTGAAAGTATTGTCGGTCATTTTACTAATCCTGTAGTCTTGCGAGGAGACCTTTCAGGAAATCCCACCTTTGAAGAGATGCTGGAGCGATCGCACTCTTGTGTATTAGATGCCCAAGACCATCAAGATTATCCCTTTTCCCTGCTGGTAGAGCAACTGCAACCTGTCCGCAACCCCAGTTTTTCGCCACTCTATCAGGTAGCCTTCGTCTGCGATCGCTCTCACCAGAATATAGATATTAATGATGATTTGATTTTGGAATCAATGATTCCAGAGTCTAAAGGAGCCGCCTTTGATTTAACCTTAACTATTTTTGAGGGCACAGACTCACTCAAAGGTACGTGGAATTATAACACCGACTTATTTGATGACAGTGCGATCGCGCGGATGATGGGGCATTTTGTAACTTTGCTCGAAGCAATTGTGGCAAATCCACAGCAACGAATTGACCAATTACCAATGCTCACACAATCTGAAGAACGGCAGTTATTAGTTGAGTGGAATGATACTCAAGTAGACTACGCCTTCGATAAATGTATTCATCAGTTATTTGAAGAACAGGTAAAGCGTACACCTGATGCTGTGGCGGTGGTGTTTGAGAATCAACAATTGACGTACCGCGAATTAAACAGCCGTGCTAACCAGTTGGCGTATTGCTTGCAGTCTTTGGGTGTGAAACCCGACGTGCTGGTGGGGATTTGTGTAGAGCGCTCCTTAGAGATGGTGGTGGGACTACTTGGCATTCTCAAGGCGGGTGGGGCTTACGTACCACTTGACCCAGAATATCCCAAAGACCGTCTGAACTTCATGCTTGCAGATGCTCAAGTTCCAGTATTAATAAGTCAACAGCGACTCCTGGATCGACTACCTGAGTATCAGGCAAAACTGATTTGTTTAGATGAAGTCTGGTCAGAAATTCTGCAAAACAAACAGAACAACCCTATTGAGGTAGTAAAGAGTACCGATCTAGCGAATGTAATTTACACATCCGGCTCCACAGGCAAACCCAAAGGGGTAATGGTTGAGCATAGTGGATTGTGCAATCTTGCTCAAGCTCAAATTCAGGTTTTCGGCTTGTCTGGTGATAGTCGAGTTCTCCAGTTTGCCTCCTTCAGTTTTGATGCTTGCATATCAGAAATCCTGATGGCTTTGGGATCTGGGGCAAGACTTTACTTAGGAACAAAAGACTCGATAATGCCGGGTATGCCTTTAATTGAGCGATTAAAGAATGATGGCATTACCCATGTTACCCTACCACCATCAGCCTTAGCAGTCCTGCCAGTAGAAGAACTGCCAACATTGCAAGCGATCGTTGTTGCCGGAGAAGCCTGTCCTCTGGAACTGATGCGACAATGGTCAAAAGGCAGAAACTTCTTCAACGCCTACGGCCCGACAGAAGCGAGTGTTTGTGCAGCGATCGCCAAATGCACTCCAGAGGACGAAAAAATTACCATTGGTCGTCCAATTGCCAATGCAGAAATCTACATTTTAGATTCACAATTACAACCAGTACCAATTGGTGTACCAGGAGAACTGCACATTGGTGGTGCGGGAGTGGCGCGAGGTTATCTCAACCGAAACGAGTTAACACAACAGAAATTCATCCCCAACCCCTTTAGTAGAAGCAGGGGAGCAGGGGAGCAGGGGAGCAGGGGGAGAGAACGTCTCTACAAAACTGGGGATTTAGCACGTTATCTGCCAGATGGCAATATCGAATACTTGGGTCGTATCGACAACCAAGTAAAAATCCGGGGATTCCGCATTGAGTTGGGAGAAATCGAAGCAACACTGAGCCAACATCCTCATGTGCAAGCATCATGTGTGATAGCCCGTGAAGATATTCCTGGTGACAAGCGCCTAATAGCCTATATCGTACTGCAACCAGAGCAGACAGCCACAGTTAAAGAACTGCGTAGCTTCCTCAAAGAAAAGCTACCAGAATATATGGTACCAAGTGCGATCGCCATCTTAGAATCTTTACCCCTAACCCCCAACGGCAAAATAGATCGTCGCGCTCTACCAGAGCCAACTAGTGAATTATCAGAGAAATATGTAGCTCCCCGCACCCCTATCGAAGAAATCCTTGCAGTAATTTGGCAACAAGTTCTGAAATTAGAGCTTGTAGGCAGACATGACAACTTCTTTGAACTAGGGGGACATTCCCTACTAGCAACGCAATTCATCTCCCGTGTGCGTAGCAGATTAAAAGTAGAAATATCATTGCGTGAGTTATTTGCTGCACCAACAATTGCCGAGTTAGCACCATCAATTCAGCAGTTACAGCAGCAAAATATAGAACTGTCAGCACCACCCATCTTAAGGCGGGTAGAGAATATAGAAATACCACTGTCTTATGCTCAACAGCGTTTATGGTTTTTAAACCAGTTAGAGTCGAACAGTGCCTTATACAACATTGCCCTTGGTTTGCGTCTAGTAGGAACTTTTAATTTTGCAGCTTTAGAACAAAGTTTAAAAGAACTTATCGATCGCCATGAAGTCTTACGCACCAACTTTGTTACTGTTGATGGAAAGCCAACACAAATAATTCAAACTCAAACAAATTGGACAGTTGCAGTTGTTGACTTGCAGCATTTACCCTTAACAGAACAACAAACTGCTGCACAGAAATTACTGGAACAAAAAGCAATTGAGCCTTTTGACTTAGCTCATGATGCCTTAATTAGAGCGACATTAGTAATGCTGTCTCCAAAAGAACAGTGCTTATTAGTGAGTATGCACCACGTTGTCTGTGATGGCTGGTCAATAGGTGTGTTTGTCCAGGAGTTACAAGCACTGTACAATGCTTATTCAATTGGTCAAGCGTCACCCCTGTTGCCACTACCAATACAGTACGCAGATTTTGCAATTTGGCAAAGACAATGGTTGCAAGGAGAGGTACTACAAAACCATTTGAGTTACTGGGAAAAACAATTGGCAAATGCACCCACATTCTTGCCACTACCCACAGATAGACCCAGACCTGCTGTGCAGACTTTCAATGGCTCATATCATGTGTTTACTCTGTCTGTTGAGTTAACTCAACGGTTGTTGGAGCTAAGTCAACAGCAAGGTTGTACTCTGTTCATGACTTTGTTGGCGGTATATAATACCCTGCTTTATCGCTACACCGGACAATCAGATATTTTGGTGGGGACACCAATTGCTAACCGCGATCGCACCGAGCTAGAACGACTCATTGGCTTTTTTGTCAATACCTTAGTGATGCGGACTGATTTAGCAGGGAACCCCAGTTTTAACGAATTACTCCTGCGCCTCAGAGAAATGGCATTATCCGCTTATGCTCATCAAGATTTGCCCTTTGAGATGTTGGTGGAAGCATTGGAACCAGAACGGGATCTCAGCTATACACCATTGTTCCAAGTGATGTTCGTTCTCCTGAACGCTCCCATGTCTGAAATAGAGTTGACTGAGTTAAGTGTCAGTGGCTTGCCAATAGAAATCACCACGTCAAAGTTTGATTTAACTTTATCAATGGAAAATACTCCCAATGGACTCTTTGGGTGGTGGGAGTATAACACTGACTTGTTTGATAGCAGCACTATCGAACGGATGACTGGTCATTTTCTGACACTACTTGAAGCGATCGTGGCAAATCCCAGCGAGCGGATTTCCCAATTGCCAATGCTCACAGCATCTGAGCAGCAACAGTTATTAGTCGAGTGGAATGATACTCAAGTAGATTATCCCCACGATAAATGTATCCATCAGTTGTTTGAAGAGCAAGTAGAGCGTACACCCAATGCCGTCGCGGTGGTATTTGAAAATCAACAATTGACGTACCACGAATTGAATTGTCGTGCTAACCAGTTGGCGCATTATTTGCGGTCTTTGGGTGTGGGAGCCGACATACTGGTGGGGATATGTGTGGAGCGTTCTTTAGAGATGCTGGTGGGATTACTTGGTATTCTCAAGGCGGGTGGAGCTTACGTACCACTTGACCCTGAGTATCCCCAAGAGCGTCTGAGCTTTATCTTAGAAGATGCTCAAGTTTCCGTGCTGCTAACCCAACAGCATTTAGTTGATAAATTACCTGAATGTCAGGCGCAGCTTGTAAGTTTAGATACTAACTGGCAGTTTATTTCTCAGTTACCTCAAGGAAATCCCATCACTAATGTCCAAGCTAGTAACTTAACTTATGTGATTTATACTTCCGGTTCTACAGGCCAGCCCAAAGGTGTGCAAATTTCACATACGGCTGTGAGCAATTTCCTATCTGCCATGCAGCAGCGCCCAGGAATAACAGAACAAGATACACTGCTTGCAGTCACTACTATTTCCTTTGATATTGCTGCCTTAGAAATTTTTCTGCCTATAACTGTAGGTGCATGTCTAGTCATAGCCCGTCGTGACGTGACCCTTGATGGAAGAGAGTTATGTGATTTGCTAGTTAAGTCTAAGGCAACAATTATGCAAGCAACTCCAGCTACTTGGAGATTGCTTTTAGACTCTAACTACCAATTTAGCGATTTAAAAATACTTTGCGGGGGTGAAGCTTTACCTTGGGATCTAGTTAGTAAATTGCTTGCTAGGAGCGCTTCTTTGTGGAACCTTTATGGGCCAACAGAGGCTACTATTTGGTCATCAATATGTCAACTCGAATCCAGCGAGAGCTTGATTTCTATTGGTCGCCCAATTTCTAATACGCAAATCTACATACTCGACCAAAACTTACAACCAGTACCTATAGGTGTACCAGGAGAACTGCACATTGGTGGTGCAGGATTAGCAAGAGGCTACTTGAAACGACCAGAGTTAACACAAGAAAAATTCATTCCCAATCCGTTTGAGGAGGCAGGAGGCAGAGGGCAGGAGGCAGGAGGGAGTAGATTATATAAAACAGGGGATTTAGCCCGTTATTTACCAGATGGTAATATCGAATACCTGGGGCGTATCGATAACCAGGTAAAAATCCGGGGATTCCGCATTGAGTTGGGAGAAATAGAAGCAGCACTGAGCCAGCATCCTCATGTGCAAGCATCATGTGTCATAGCTCGTGAAGATACTCCTGGTGACAAGCGCTTAGTTGCCTACATCGTACCTCAACCACAAGTAACACTCACAATTAGCGAACTACGTAGCAACCTCAAGGAAAAGTTACCAGACTACATGGTTCCTTCGGCAATAGTTATCCTGGAGTCTTTACCGCTAACTCCCAATGGCAAAATAGACCGTCGCGCTTTACCAGCACCAGAGCCAAGTAGTGAATTATTAGAGAAATATGTCGCCCCACGCAACCCCATCGAAGAAATACTGTCACTGATTTGGCAACAAGTCCTAAAAGTAGACCTTGTAGGCAGACATGATAACTTCTTTGAGCTAGGGGGACACTCACTATTAGCAACGCAACTTATTTCCCGTGTGCGTAGCAGCTTGAAAGTAGAACTGCCATTGCGATCGCTATTTGCTGCACCAACGATCGCTGAACTATCGAATAACATTCAACAGTTACAGCAACAAGACTTAGAACTTGCCGCAGCACCGATTTTAAGGCGGGCAGAGAATGCAGAAACACCACTGTCTTATGCTCAACAGCGTTTATGGTTTTTAGACCAGTTCGAGCCGAACAGTGCCTCATACAACATTCCTTTCGGGTTGCGTTTAGTAGGAACTCTTAATGTTGTCGCCTTAGAACAAAGCTTAATTGAAATTATTCATCGCCACGAAGCATTACGCACTAACTTCATCACAGTTGATGGACAAGCTACTCAAATCATTCACAATTGGAAGGAACAGGGAACAGGGAACAGGGAACAGGAAAATATACCCTGGACACTATCAGTTGTTGACTTAAAGCATTTACCTTTAACAGAACAAAAAACTGCTGCACAGAAATTAGTCCAAGAACAAGCGTTTCTTCCTTTTGACTTAGCTCATGATGCATTAATCAGAGCGACATTAATAGTACTGTCTCCTACAGAGCAGTGGTTATTAGTGTGTATGCACCACGTTGTCTCTGATGGCTGGTCAATAGGTGTGTTTAGCCAGGAGTTACAAGCACTGTACAATGCTTATTCTCAAGGTCAACCGTCACCTTTGTTGCCACTACCAATTCAGTACGCAGATTTTGCAATTTGGCAAAGACAATGGTTGCAAGGAGAGGTTCTACAAAGCCAATTAAGTTACTGGAAACAACAATTGGCAAATGCACCTACGTTCTTGCCATTACCCACAGATAGACCTAGACCTGCTATACAGACTTTCAATGGCGCATATCAAGAGTTTGCTTTGTCGAGTGAACTAACTCAACGGTTAGTGCAGCTGAGTCAAAAGCAAGGGGTGACTTTGTTTATGACTCTGTTGGCGGCATATAATACTCTGCTTTATCGCTACACAGGACAAACAGATATTTTGGTGGGGACACCAATTGCTAACCGCGATCGCACCGAGATAGAAGGACTCATTGGCTTTTTTGTCAATACTTTGGTGATGCGGACTGATTTATCTCTTAATCCTAGTTTTAACGAATTACTCCCACGTATCCGGGAAATGGCATTATCCGCATACGCTCATCAAGATTTGCCCTTTGAAATGTTGGTGGAAGCATTGCAGCCAGAACGGGATCTCAGCTATACACCACTATTTCAGGTGATGTTCGTTCTCAATAATGCGCCCACATCTGAAGTAGAGTTGACTGGGTTAAGTATCAGTTCTTTGCCTATAGAAAGTGCGATCGCCAAGTTTGATTTAACTTTATCAATGGAAAACACTAGCACTGGTTTAGTGGGAGGGTGGGAATACAACATTGACTTGTTTGATAGCAACACAATTGAACGGATAACTGGTCATTTTGTGACATTGCTAGAAGCTATTGTTGCTAATCCTCAAGAGCGGATTTCTCAATTACCAATGCTCACAGCATTTGAGCAACAACAATTATTAGTTGAGTGGAATGATACAAGCGTAGATTATCCCCAAGATAAATGTATTCATCAGTTGTTTGAAGAACAGGTGGAACGCATCCCCGATGCTGTAGCGGTAGTGTTTGAGAATCAACAATTGACTTACCACCAGTTGAATTGTCGTGCTAACCACTTAGCGCATTACTTGCAGTCTTTGGGAGTGTCCGCCGATGTGCTGGTGGGGATATGTGTGGAGCGCTCTCTGGAGATGGTGGTGGGATTACTTGGTATTCTCAAGGCGGGTGGGGCTTACGTACCACTTGACCCTGAGTATCCCCAAGAGCGTCTGACTTTCATGCTGGCAGACGCTCAAGTTTCTGTGCTGCTTACTCAACAGCATCTAGTTGAGAAATTACCTCGACATCAAGCGCGTGTAGTCCACTTAGATAAAGACTGGGTTGCGATCGCTAAGTCCAGCCAAGAGAATCCAATTGCCCAGGTGCAAGCTAGTAACGTAGCTTATGTGATTTATACTTCTGGCTCTACTGGTCAACCGAAGGGGGTAATACTATCTCACAGTAACCTTTGCAACCACATGTTCTGGATGCAAGCAACATTCCCCCTGACTAAAGAAGACAAAGTACTGCAAAAAACTCCCTTTGGCTTTGATGCCTCAGTTTGGGAATTCTATGCTCCATTGTTAGCAGGTGGACAGTTGTTAATAGCTGAACCCAGAGGTCATACTGACAGTGCTTATCTCTTAAGGTTAATTGCCCAGCAGCAGGTAACTACTATTCAACTTGTTCCATCTTTACTGCAAATGCTTTTAGAACAGGGAGGAATCGAAACTTGTCACTCCCTCAAACACGTGTTCTGTGGCGGTGAAGTCTTACCCGTTACTCTGCAAGAAAGCTTGTTAAGTAAACTAGATGTAAATTTACACAATCTCTACGGCCCAACAGAAGCTTGTATTGATGCAACTTTCTGGAATTGTCAGCGTGAGATTTATCCACAACTTATCCCTATTGGTCGTCCAATTGACAACACCCAGATATATATACTCGACCAAAACTTACAACCAGTACCTGTGGGTGTACCAGGAGAACTGCATATTGGTGGTGCAGGATTAGCAAAAGGATACCTCAACCTTCCAGAGTTAACGCAAGAAAAATTTATCCCCAACCCCTTCCAAGGAAGCAGGGGAGCAGGGGAGCAGGGGAGCAGGGGGAGAGAACGGTTGTATAAAACAGGGGACTTAGCACGTTATCTACCAGATGGCAATATCGAATACCTGGGGCGCATCGATAATCAAGTAAAAATCCGGGGTTTCCGCATTGAGTTGGGAGAAATCGAAGCAGCATTAAGCCAACATAGTGATGTGCAAACATCTGTAGTCATCGTCCGCGAAGACATTCCCGGAAATAAACGTTTAGTCGCTTATGTAGTACCGCAGCCACAGATAACACCCACAGTTAGCCAATTGCGTAGCTTCCTCAAAGAAAAGCTACCAGAATATATGGTACCAAGTGCGATCGTCACCCTAGAATCCCTACCGCTTACCCCCAACGGCAAAATAGACCGTCGCGCCTTACCAGAACCAGAAGCACGCACAGGAATAGAAAGCAGCCTAGTAGCACCGCGTACCCCCATTGAAGAAAAATTAACCCGAATTTGGGAGCAAGTATTAAGAGTAGAGCAAATAGGCATACACGATAACTTTTTTGAACTAGGAGGAGATTCCATCCTCAGTATTCAAATCATCAGCAGAGCAAAAGTTGCCGGAATAGAACTGACAATCAAACAACTATTTGCCAATCAAACCATCGCCCAATTAGCCACAGTCGCAGGTACAACAAAAGCACTTGCAATTGAACAAGGATTAGTCACAGGGACATTACCCCTAACACCAATTCAACACTGGTTTTTCGAGCAGAAATTACCAGAGAAACACCACTTTAATCAATCATTTCTCCTCACAGTACCATCAGACCTCAACCTAGAAATATTAGAGCAAGTATGGCAGCAACTACTAAAACATCACGATGCTCTTAGGCTAAGATTCACTCGAACAGACACAATATGGCAGCAGATTCATGCTGCGCCAACTGATAATATTACTATCCCCCGTTTTGACTTATCGACAGTTCCAGAAACTGAGATAGAAACTGTCATCGAAACCACAGCCAATGAATTACAGGCGAGTTTAAATCTTTCAGAAAATCTCGTGCAAGTAGCATTTTTCTGGTTGGGTATTGACAAAAAAGCCAGATTAATAATAGTAATTCACCACCTCGTAGTAGACGGTGTTTCTTGGCGGATATTATTAGAAGATTTGCAGACAGCTTACCAGCAACTCAGTCAAGGCAAAACCATTCAGCTACCTGCAAAAACTACATCTTTCAAAGATTGGGCGCGACAACTGACAGAATATGCACAATCAGAAGTCTTGAAATCAGAACTAGATTATTGGTTGAGTCCATCTTACGATACAGTTGACTCCATCCCGGTAGACTATGCACAAGGAATAAACACTACTGCATCGGCTAGGACAATATCAGTATCATTAGATGAAGCTGAAACCCTTTCACTTTTACAAGATGTTCCGAAAGCTTATAAAACACAAATAAACGATATCTTGTTAACTGCCTTAGTACTGGTGTTGAGCGAATGGACTAACTCTGATTCAGTGTTATTCAACTTAGAAGGTCATGGGCGGGAGGAGATTATTGATGGTGTAGACTTATCGCGCACCGTTGGTTGGTTTACAACGATTTTTCCAGTGGTTGTGGAACTGGGAACTATAGATGATCTTGGTACTGCGTTAAAATCCGTCAAGGAACAATTACGTGTAATTCCTAATAAAGGCATTGGCTATGGCTTATTGCGTTATCTAAATATTGACGCAGAAATTAGCACCCAATTAGAAAAAATTCCCCAGGCAGAAATTAGCTTCAACTATTTGGGACAATTTGCTCAAGTTGTCAATACATCCTCTCTGATGCAAATAGCTAATGAACCTAGCGGAAACAGCCAGAGTTTACAAGGTCAACGCCATTATTTGCTAGATATTAATGCCATCATTATCAACGAAAAACTGCAAATAGATTGGACATACAGCAGCAATATTCATCAGTACGAAACGATTGAGAATATTGCTCAAGAATTTGTCGAAACTTTGCAAGAGTTAATTGCTCATTGTTTATCAACAGAAAATGCAGGTTATACGCCTACGGATTTCCCATTAATTCAACTTAACCAACTAGAAATAGATCAGATATTACAAAATTTATGAAATTAGAACTTAGCAAAACTAATCGCCAAAATATTGAAGATATTTATCCCTTATCTCCCATGCAAGAGGGGATGCTGTTTGAAAGTTTATATGCTCCAGACTCAGGCGTATATTTTGAGCAGATAACTTGCATTTTGACGGGAAACCTAGATGTAAAAACTTTCGAGAAAGCTTGGCAGCAAGTAGTAGCTCGACATCCCGTCTTCCGCACAGCGTTTCTGTGGGAGTCTTTGAGCCAGCCAGTTCAAGTGGTGTATCGACAGGTAAATGTGACGGTCGAAACTTATGACTGGCGGGAGTTATCTACACAAGAGCAGCAACAGCAATTAGAGAGTTTTCTGGATTCTGAGCGACAACAGGGTTTTCAAGTGTCGCAAGCGCCATTGATGCGTCTACATCTAATCCAGTTGGATGGGGATACTTATCAGTTTGTTTGGTGTCATCATCATTTATTACTTGATGGCTGGTCATCACCTTTGGTTTTCCAAGACCTGTTGGAGTTTTATCAAGCTATTTCTCAGGGTAAAAGTTTATCTAATACGGGAACTGTCAGCTACCGCAACTATATTGCTTGGTTACAGCAGCAGGATCGAGATTTAGCTAAAGAATTTTGGCGACAAAAACTCCAAGGTTTTACTACACCAACTCCTTTGACTGTGGATAAACCATTGTCAATGCGGGAGAAACATTCGGGCTATAGCGAACAACAAATTGACTTAACTGTGCCAGCGACAGCAGCAGTAATGTCTTTTGTCAGACAGCATCAATTGACGATGAGTAATTTGGTGCAGGCGACTTGGGGATTGTTGCTGTCTCGCTACAGCCAAGAAACAGATGTGGTTTTTGGCGCAACTGTATCTGGTCGTCCGCCTGAGCTTGTTGGTGTAGAGTCGATTGTGGGGTTATTTATCAATACTCTGCCAGTGCGGGTACAAATCTCCGAGAAGACTGAATTGCTGGGTTTGTTGAAGGATTTACAGGCGCAACAGATTGAGTCTGAGCAATTTTCCCATAGCTCATTAGCAGAGATTCAGGGGCTAAGTGATGTTCCCAAGGGTACGCCTTTGTTTGAGAGTATTGTTGTTTTTGAGAATTATCCTATTGATACTTCTGCTCTACAAGGCGATCGCAATTTTTCCCTCTCGAATTTTAGATGGATTGAACAAACAACTTATCCTCTGGCGGTTGTAGTTTCCCCTGGTGAGCAATTATCGCTGAGGGTGATGTACGATGCTAGTCGATTTGAAGATGGAACGATTAGCCGGATGCTGGGTCATTTTGTAACAATGCTTGAGGCGATGTCTGACGACAAGCCGCTTTGCGTCTACGCTACTAATCCTCAGCAACGAATTTCCCAGTTGCCAATGCTAACAGAATCTGAGCAGCAACAGCTATTAGTTGACTGGAATGATACCCAATCTAATTATCCCCAGGATAAATCTATTCATCAGTTGTTTGAGGAGCAGGTGGAGCTTACACCCGATGCTGTAGCAGTGGTGTACGAGAATCAACATCTCACATACCGCGAATTGAACAGCCGTGCTAACCAATTGGCGCACTACTTGAAGTCTTTGGGTGTGAAAGCTGATGCGTTGGTGGGGATATGTGTGGAGCGTTCTTTAGAAATGGTCGTGGGACTATTGGGGATTCTCAAGGCGGGTGGTGCTTATGTGCCACTTAACCCAGAATATCCTCAAGAGCGATTGACCTTCATGCTCGAAGATACTCAGTTATCAGTCATATTGACTCAAGAAAAACTAGTTAATAAACTAGGCGAACGCCTCCGGCGCGGCTTTGCCGAACGCAACGCTAGTGTAATTTGCTTAGACTCAAACTGGGATATCATCAATCAACAAACACAAAATAACCCAACTACCAGCGTCACAGCTGATAACTTAGCTTATGTAATGTACACCTCCGGTTCTACAGGTCAACCCAAAGGTGTGAGCATTGTCCATCGAAGTGTAGTTCGACTCGTCAAAGAAACCAACTATATCAGCATTTCTGCTGATGATGTAATTGCCCAAGCCTCAAATCACGCCTTCGATGCTGCTACTTTTGAAATTTGGGGAGCCTTACTCAACGGAGCGCGGTTGGTAGGGGTGAGCAAAGATTTGGCACTTTCGCCCAGAGATTTCGCAGTCTTTATGCGATCGCAAAGTATCAGTGTATTATTCTTGACAACTGCCCTGTTTAATCAAATTGCTCAAGAAGTCCCCTCTGCTTTCAATTCACTACGGCATCTTCTATTTGGCGGCGAGGCTGTCGATCCTAAATGGGTTAAAGAAGTACTCAACAATGGTGCGCCGCAGCGACTACTCCATGTTTATGGGCCAACAGAGAATACAACATTTAGTTCCTGGTACTTGGTGCAGGATGTGCCAGAAGGCGCGACAACTATTCCCATCGGGCAACCAATTTCTAACACACAAATCTATTTGTTAGATTCCCAACTACAACCAGTGGGTATTGGTGTACCGGGAGAATTATACATTGGTGGAGATGGTCTAGCTAGGGAATACCTTAACCGCACCGAGTTAACACAAGAAAAACTCATCCAAAACCCCTTCGGTGGAAGCAGGGGAGCAGGGGAGCAGGGGAGCAAGGGAGCAGAGGAGCAGTCTTTCCCCTCTGCCTCTTCTGAGCGCCTCTACAAAACCGGGGATAAAGCACGTTATTTAAGCGATGGAAATATTGAATACTTAGGACGCATCGATGACCAAGTAAAAATACGTGGTTTACGGATTGAGTTGGGCGAAATTGAAGCAGTCCTGAGCCAACACAGCGATGTGCAAGTATCTTGTGTCATTGTCCGCGAAGATACCCCTGGAGATAAACGTTTAGTCGCCTACATCGTAACGCATCAAGACTGTCAACCTACGATGGGTGAAATACGTCAATTCCTCAAAGCAAAGCTGCCAGATTACATGATACCTTCGGCAATAGTAATCTTGGAATCTTTCCCCTTGACTCCCAACGGCAAAATAGACCGCCGCGCCCTGCCAAAACCAGACTTAGACACCGCACTCCTAGAAAAATATGTCGCCCCGCGTACACCTGTTGAGGAAATGCTTGCACTCCTCTGGGCGCAAGTTTTGAAAGTAGAGCAAGTGGGTATTTACGATAATTTCTTTGAACTTGGGGGACACTCACTCTTAGCAACGCAATTGGTTTCACGCATCCGCACTAGCTTCAAAATAGAACTACCATTACGTGAGTTATTTGCTGCATCAACAATTACGGAATTAGCGCCATTCATTCAGCAGTTACAGCAACAGGACTTACAACTTGCTGCACCACCCATTTTAAGGCGGGCAGAGAATGCAAACTTACCACTGTCTTATGCTCAACAGCGTTTGTGGTTTTTAGACCAGTTCGAGCCGAACAGTGCTTCATACAACATCCCCTTCGGGTTGCGCTTAGTCGGAACTCTTAATGTTGCCGCGCTACAACAAAGCTTAATTGAAATTATTCATCGCCACGAAGCATTACGTACTAACTTTATTACTGTTGATGGACAAGCTGCTCAAATCATTCACAATTGGAGGGAACAAGGAACAGGGAACAGGGAACAGGAAAATATACCTTGGACACTATCAGTTGTTGAGTTAAAGCATTTACCCGTAACAGAACAAAAAACTGCTGCACAGAAATTAGTCCAACAACAAGCACTTCTTCCTTTCGACTTAGAGTCAGAAGCATTAATCAGAGCAACATTACTGGTGCTGTCTCATACAGAACAATGGTTAGTATTGTGTATGCACCACGTTGTCAGTGATGGCTGGTCAATAGGTGTGTTTATCGAGGAGTTACAAGCACTGTACAATGCTTATTCTCAAGGTCAACCGTCACCCTTATTACCACTGCCAATTCAGTACGCAGATTTTGCAATTTGGCAAAGACAATGGTTGCAAGGGCAAGTACTCAACAGCCAATTGAGTTACTGGAAACAACAATTAGCGAATGCACCCACGTTCTTGCCACTACCCACAGACAGACCCAGACCTGCTGTGCAGACTTTCAATGGTGCATATCAAGAATTTACTCTGTCTGGTGAACTAACTCAACGATTGGTGCAGTTAAGTCAAAAGCAAGGGGTGACTTTGTTTATGACTTTGTTGGCGGCTTATAATACCCTGCTTTATCGCTACACAGGACAAGAAGATATATTGGTGGGTTCGCCAATTGCTAACCGCGATCGCACCGAAATTGAAGGGTTAATTGGCTTTTTTGTCAATACCTTAGTCATGCGGACTGAGATATCAGGCGATCGCAGTTTTAACGAATTACTCCCACGTATCCGGGAAATGGCATTATCCGCTTATGCTCATCAGGATTTGCCCTTTGAAATGCTAGTGGAAGCATTGCAACCAGAACGGGACTTGAGCCATACACCACTGTTTCAAGTGATGTTTGTTCTTAATAATGCGCCCACATCTGAAGTAGAGTTGACTGGGTTAAGTGTCAGTGAATTGTCAATAGAAAGTGCGATCGCTAAGTTTGACCTTACCTTAGGAATGCAAAACACTAACAATGGACTCGTCGGGTGGTGGGAGTACAACACTGACTTATTTGATAGCAGCACTATCAAACGGATGACTGGTCATTTTGTGACTCTACTTGAAGCAATTGTGGCGAATCCCCAAGAGCGGATTTCTCAATTACCAATGCTCACAGCATCTGAGCAACAACAATTATTAGTGGAGTGGAATGATACTCAAGTAGATTATCCCCAAGATAAATGTATTCATCATTTGTTTGAAGAACAAGTAGAGCGTACACCCGATGCAGTCGCGGTGGTATTTAAAAATCAACAATTGACGTATCACGAGTTAAATTGTCGTGCTAACCAGTTGGCGCACTACTTACGTTCTTTGGGAGTGTCCGCAGATGTGCTAGTGGGGATATGTGTAGAGCGCTCTTTGGAGATGGTGGTGGGATTGTTGGGAATTCTCAAAGCTGGTGGGGCTTACTTACCGCTTGACCCAGAGTATCCCCAAGACCGTTTGAGTTTTATGCTCGAAGACGCTCAAGTTTCAGTATTACTGAGTCAACACCATCTAGTTGAGAAATTACCAGAACATCATGCGCGTGTTGTTTGCTTAGATACCGACTGGCAAATCATTCCCCAGTCGAATCAACAAAATCCGATCGCTGGTGTGCAAGCTAGTAACTTGGCTTATGTAATTTACACTTCGGGTTCCACCGGAAAGCCTAAAGGAGCAATAAATACGCATCTAGGGATTTGCAATCGCCTCCTGTGGATGCAGCAAGCATATCAATTAACAGAAATAGATTGCGTTTTACAGAAAACTCCTTTCAGCTTCGATGTCTCCGTTTGGGAATTTTTCTGGCCATTACTGACTGGAGCGCGTTTAGTTGTAGCTAAACCAGATGGACATAAAGATAGTGGTTACTTGGTCAACCTAATACTAGAACAGCAAGTTACTACACTGCATTTTGTTCCTTCGATGCTCCAGATTTTTCTAGAAGAACAAGGTTTAAAAGATTGCAGTAGCTTGAAGCGAGTTATTTGTAGTGGTGAAGCACTGCCAAAAGAACTTCAGGAACGCTTTTTTGCTTGTTTAGGGTGTCAATTGCATAATCTCTACGGGCCGACAGAAGCGGCGATTGATGTCACCTTCTGGGAATGTCAACCAGAGAGCAATTTGAAGACAGTGCCTATTGGTCGCCCAATTTCCAATACGCAAATCTACATACTCGACCAAAACTTACAACCAGTACCTGTGGGTGTTCCAGGAGAGTTACACATCGGTGGTGCAGGATTAGCAAAAGGATACCTCAACCGCCCAGAGTTAACACAAGAGAAATTCATCCCCAACCCCTTCAGTGGAAGCAGGAGAGCAGGGGAGCAGAGGAGCAGAGGGGCAGGGGAGCGGAGGAGAAAAATAGTGCAATCTCCAGTTGCCAGTCCCCGCCTCTATAAAACCGGAGATTTGGCTCGTTATTTACCAGATGGCAATATAGAATATCTGGGACGTATCGACAATCAAGTAAAAATCCGTGGATTCCGTATCGAATTGGGAGAAATCGAGGCAGCACTAAGTCAACATAAAGATGTGCAAACATCTGTAGTCATCGTCCGCGAAGATATTCCTGGTGATAAGCGCCTAGTCTCGTACATCGTACTGCAACCAGAGCAGACAACCACAGTTAAAGAACTGCGTAGCTTTCTCAAAGAAAAGCTACCAGACTACATGGTACCAAGTGCGATCGCCATCTTAGAATCTTTACCCCTAACCTCCAACGGCAAAATAGACCGTCGCGCCTTACCAGCACCAGAGCCAAGTGGTACATTATCAGATAAATATGTAGCTCCACGCACGCCCCTAGAAGAAATCCTGGCACTTATTTGGCAAGAAGTCCTAAAAATAGAGCTTGTAGGCAGATATGATAACTTTTTTACCTTGGGAGGACACTCGCTATTAGCAACGCAACTCGTCTCTCGTATCCGTAGCAGCTTGAAAGTAGAACTGCCATTACGTTCGTTATTTGCTGCACCAACAATTGCAGAGTTAGCACAATTAATTCAGCAATTACAGCAACAAGACTTAGAACTTGCCGCACCACCCATCTTAAGGCGGACAAACAATGCAGAACTACCATTGTCTTATGCTCAACAGCGTTTGTGGTTTTTAGACCAGTTCGAGCCGGACAGTCCCTTCTACAACATCCCAATTGGGTTGCGCTTTGTCGGAAGTGTGAATATTGCCGCTTTGGAACAAAGCTTCAAGGAAATTATTCATCGCCACGAAGCATTACGCACTAATTTTGTTTCCGTTGATGGAAAACCAACTCAAATCATTCATCAAATAGAACCGAATTGGTCACTGACAGTTGTTGAATTGCAGCATTTAGCCTTAACAGAACAAGAAATAGCTGCACAGAAATTAGTCCAACAACAAGCAATTGAGCCTTTTGACTTAGCTCATGATGCATTAATCAGAGCCACATTAGTGGTGTTGTCTCCTATAGAACAGTGGTTATCAGTGTCTATCCATCACGTTGTTAGTGATGGCTGGTCAATAGGTGTGTTTGTTGAGGAATTACAAGCGCTGTATAATGCTTATTCTCAAGGTCAACCGTCACCCTTATTACCACTGCCAATTCAGTACGCAGATTTTGCAATTTGGCAAAGACAATGGTTAGTGGGGGAAGTACTCAACAACCAATTGAGTTACTGGAAAGAACAATTGGCTAATGCACCTACCTTCTTGCCACTACCCACAGACAGACCCAGACCTGCTGTGCAGACTTTCAATGGCGCATATCTTGAGTTTGCCCTGTCTGTTGAGTTAACTCAACAACTAACCAAACTGAGTCAACAACAAGGGGTGACTTTGTTTATGACTTTGTTGGCGGCTTATAATACCCTGCTTTATCGCTACACCGGACAAGAAGATATATTGGTGGGTTCGCCAATTGCTAACCGCGATCGCACCGAAATAGAAGGGTTAATTGGCTTTTTTGTCAATACCTTAGTCATGCGGACTGAGATATCAGGCGATCGCAGTTTTAGCGAATTACTGACTCGCGTCCGTGACATGGCAATGGAGGCATACGCTCATCAGAACTTACCTTTTGAAATGCTGGTAGAAGCATTACAGGCAGAACGGAATCTTAGCCATACACCACTGTTTCAGGTAATGTTTGTCCTCCAAAATGCGCCCACTGCATCTGGATTAGACCTAACTGGGCTAAATGTCAGTCCATTACCAGTAAAACTGACAACTTCCAGGTTTGATTTAACCTTAATCATGCAGAACAGTCCTACTGGGCTGATAGGATTGTGGGAGTACAGCACTGACTTGTTTGATGCTAGTACTATCGATCGCATGACAAGTCATTTTGTCACCTTGCTTGAAGGCATTGTTGCTAATCCTCAACAGCAAATCTCACAATTGCCTCTGCTGAGTGAAGTTGAGCAACAAAAATTACTTTTTGAGTGGAACGATACTCAAGTTGATTATCCCCTTGATCAGTGCATTCATCAGTTGTTTGAGGAACAGGTAAAACTGACACCCAATGCAGTGGCAGTGGAGTTTAAAGAGCAACAACTTACTTACAACCAATTAAACGATCGCGCTAACCAGTTGGCGCACTACTTGCAGTCTTTGGGTGTAAAACCAGATACCTTAGTTGGTCTATGTGTAGAACGTTCTTTGGAGATGGTCATTGGACTGTTGGGAATTCTCAAAGCAGGGGGAGCGTATGTACCACTTGATCCAGAGTATCCAACTGAGCGTTTGAGCTTTATTTTAGAGGATACTCAAGTTAAAGTCTTGCTCACCCAGCGATCGCTTCTTGACCGACTGCCCCAGTGTGAAAAAGCAGGGGGGCAGGGAGCAGGGAGCAGGGGAGAAAGTCCATCTACAAGGGATAGGGCTTCAACCAAAGGGAAAGAGGAGGTTTTGAGTCTTCCTGCTTCTTATCAAACACAGCTTGTTTGCCTAGATACTGACGCTGAATTAATTTCTCAGTGCAGCCAGGATAATCTCATCACTGGCGTACAAGCTAATAACTTAGGTTACATAATTTACACTTCTGGTTCTACAGGTCAACCAAAGGGTATAGCCATGAATCAGCTTGCCCTTTGCAATCTGATTTTGTGGCATCCAGACAATCTGAAAATTGCTCGTGGAGCAAAAACCCTACAATTTGCTTCGATTAACTTTGATGTCTCCTTCCAAGAAATCTTCACTACTTGGTGTTCTGGCGGTACATTGTTCTTAATAACTAAGGAATTACGCCACGATACCTCAAATTTGTTAAGAGTAATCCAAGAAAAAGCAATTCAAAGAATGTTTCTCCCCGTTGTGGGATTACAACAACTAGCAGAATTCGCTGTTGGTAGTGAGTTAGTAAATACTCATTTGCGGGAAATCATTACTGCTGGGGAACAGTTGCAGATTACTCCTGCCATTTCCAAGTGGCTGAGTCAGCTAAGTGACTGTACTCTGCACAATCATTACGGGCCATCCGAGAGCCATGTAGCCACCAGTTTTACTTTGCCTAATTTAGTAAACACTTGGCCGCTACTACCTCCAATTGGGCGACCTATTTCTAATACTCAAATCTACATCCTAGATAAATATTTACAGCCTGTACCCATTGGTGTACCAGGGGAAGTGTACATTGCTGGTGTGCTTTTAGCCAGAGGCTACTTGAACCGCCCAGAGTTAACACAAGAAAAATTCATCCAAAACCCCTTCGGTGGAAGCAGGGGAGCAGGGGAGCAGGGGAGCAGGGGAGCAGAGGAGCAGTCTTTCCCCTCTGCCCCCCATTCCCTCTGCCCCTCTGCCTCTTCTGAGCGCCTTTACAAAACTGGGGATCTAGCACGTTATCTGCCAGATGGCAATATCGAATACTTAGGACGCATTGACAATCAGGTGAAAATTCGCGGTTTCCGCATCGAGTTGGGCGAAATTGAAGCTGTACTGAGCCAACATATTAATGTACAAGCTTCTTGTGCGGTTGTGCGAGAAGATACCCCAGGTGATAAACGCTTAGTCGCTTACATTGTGCCACAGCCAGAGCAGAGAGTCTCTGTAAACGTTGTGCGTAGCTTCCTGAAGGAGAAGTTACCAGAGTATATGCTGCCAAGTGCAATAGTTATCTTGGAAGCTCTACCGATTACCTCCAACGGAAAATTAGACCGTCGCGTATTGCCTGCACCTGATTTACACAGTCAATTATCAGATCAGTATGTTGCTCCACGTAACCCAATTGAAGAAATTTTGTCACTAATTTGGGCGCAAGTGCTGAAAGTAGAGCTTGTGGGCATACATGATAACTTCTTTGAACTTGGAGGACATTCGCTACTAGCAACGCAACTGGTTTCCCGCATCCGCACCAACTTGAAAGTAGAACTGCCATTACGTGAGTTATTTGCTGCACCAACAATTGCTCAATTAGCGCCAATTATTCAACGGTTACAGCAACAAGACTTAGAACTTATTGCCCCACCCATCTTAAAGCGGGCAGAGAATGCAGAACTCCCACTGTCTTATGCTCAACAGCGTTTGTGGTTTTTAGACAAGTTAAACCCGAACAGTGCCTCATACAACATCCCCATTGGTTTGCGCTTAGTCGGAACTGTTAATGTTGCCGCCTTAGAACAAAGCTTGATTAAAATTATTCATCGCCACGAGGCATTACGTACTAATTTTATTACTGTTGATGGAAAGCTTTCACAAATTGTTCAAACTCAAACGAATTGGACAGTTGCAGTTGTTGACTTACAGCATTTACCCGTAACAGAACAAGAAATCGCTGCACAGCAATTAGTTCAACAACAAGCAATTCAGCCTTTTGACTTAGCAAATGAAGCATTAATCAGAGCGACATTAATGATACTGTCCGAGACAGAACAGTGGTTATTAGTGTGTATGCACCACGTTGTCTCTGATGGCTGGTCAATAGGTGTGTTTGTCCAGGAGTTACAAGCACTATACAATGCTTATTCTGAAGGTCAACCGTCACCTTTAACACCACTGCCGATTCAGTATGCAGATTTTGCCTTATGGCAAAGACAATGGTTGCAAGGAGAAGTACTGAAGAGCCAATTGAGTTACTGGGAACAACAATTGGCAAATGCACCCACGTTCTTGCCATTACCCACAGATAGACCTAGACCTGCTGTGCAGACTTTCAATGGCGCATATCTTGAGTTTGCCTTGTCTGGTGAACTAACTCAACGGTTGGTGCAGCTGAGTCAAAAGCAAGGGGTGACTTTGTTTATGACCTTGTTAGCGGCATATAATACCCTGCTTTATCGCTACACGGGACAATCAGATATTTTGGTGGGGACACCAATTGCTAACCGCGATCGCACTGAAATAGAAGGGTTAATTGGCTTTTTTGTCAATACCTTAGTCATGCGGACTGATTTATCTCTTAATCCTAGTTTTAACGAATTACTCCCACGTATCCGAGAAATGGCACTGTCCGCCTACGCTCATCAAGATTTGCCCTTTGAGATGTTGGTGGAAACTCTGCAACCAGAAAGAGACATGAGTCATACACCACTATTTCAGGTGATGTTTGGTCTCCAGAACGCTCCCATGTCTGAAATAGAGTTGACTGGGTTAACTGTAAGTTCCTTGCCAATAGAAAGTTCCACGGCAAAGATTGATTTAACTTTATCAATGGAAAACACTAGTACTGGACTAGTGGGAGGGTGGGAATACAACACTGACTTGTTTGATAGCAGCACTATCGAAAGGATGACGGGTCATTTTCTGACACTGCTAGAAGGTATTGTTGCTAATCCCAGCGATCGCATTTCTCAATTGCCAATGTTAACAGCATCTGAGCAACAGCAATTATTAGTTGAGTGGAATGATACTCAGGTAGACTACGCCTTCGATAAATGTATTCATCAGTTGTTTGAAGAACAGGTGGAACGTACACCCGATGCCGTGGCGGTGGTATTTGAGAATCAACAACTGACTTACCACCAGTTGAATTGTCGTGCTAACCAGTTGGCGCATTACTTGCGCTCATTGGGTGTCAAACCAGATGCGCTGGTGGGTATTTGTGTAGAACGTTCTTTAGATATAGTGGTAGGACTGTTGGGGATTTTCAAGGCTGGTGGAGCTTATGTAGCCCTTGATCCAGACTATCCTCAAGAGCGCTTGCGCTTCATGTTAGAAGATGCTCAAGTTTCGGTACTGCTGACTCAACAACGACTTATTCACAGACTTCCTGAGCATCAAGCAAAACTTGTCTGCCTAGATGAAGCCTGGGAAGAAATTGCCCAAAACAATCAAGATAACCTCAGCAGTGGAGTCAAAGCTTCTCATCTAGCTTATGTGATTTACACTTCAGGATCTACAGGTAGACCTAAAGGTGTCATGGTTGAGCATAGGGGACTATGCAACTTAACTCACGCTCACATTCAAACTTTTGGCTTAGACTCTGATAGTCGCGTTCTCCAGTTTGCCTCCTTCAGTTTTGATGCTTCTATCTGGGAAGTTGTATTGGCTCTGGGGTCAGGTGCAACGCTGTACCTGGGAACAAAAGACTCTCTATTGCCAGGGAAGCCATTAATTGAGCAATTACGCAATAATTGCATTACCAATATCACGCTACCACCATCGGCTTTAGCAGTTATGCCTATGGAGGAACTTCCGGCACTGCAAACAATAATTGTAGGTGGAGAAGCTTGTTCTGCTGAACTAATCAGACAATGGTCTGCTGGCAGAAACTTCTTCAACGGTTACGGGCCAACAGAAGCTACTGTCTGTGCCACGATTGCAAAATGCACTGAAGATGACGAGAAAATATCTATTGGTAAGGCGGTCGCCAATACACAAGTCTACATTTTAGACGAAAATTTGCAACTAGTGCCTGTGGGTGTGCCAGGAGAATTGCACATCGGTGGTGCAGGATTAGCACGCGGTTATCTCAACCGACCAGAATTAACACAAGAAAAATTCATCCCTAACCCCTTTGCTGGGAGCAGGGGAGCAGGGGAGCAGGGGAGCAAGGGAGCAGAAATTCTTCCCAATTCCCAGTCCCCAGTCCCCAGTCCCCGACTTTACAAAACTGGTGACTTAGCCCGTTATTTACCAGATGGAAACATAGAATACCTGGGACGCATTGACAATCAAATAAAAATCCGAGGTTTCCGAATTGAGGTAGGGGAAATTGAGGCAATACTGAGTCAGCATCCAGGAGTTAGAGAAAATGTGGTAGTTGCGAGAGAAGATATCCCAGGAGAGAAACGCTTAGTAGTTTATTTTGTGCCGCAGTTGGAGCAAACACCAACTACCGATGACTTACGCATTTTCTTGAAAGAAAAATTACCACAGTACATGGTGCCTTCTGCTTTTGTCAGGTTAGAGTTTTTACCTTTAACTCCCAATGGCAAGGTAGACCGCAAAGCCTTACCTATTCCTGATTCCCATAATACCCAGTTGGCAGTGAGCTTTGTAGCACCACGCACCCCTGTAGAGAAGGTCTTGGCAGATATTTGGGCTAATGTACTGCATTTGGAGCAGGTGGGTGTTTTAGATAATTTCTTTGAGTTAGGAGGTCATTCACTCTCCACAATTCGAGTGATGTCTCAGGTAAATGAGACTTTCCAGATTAACTTACCGTTGCGCCACTTATTTGCTGCCCCAACTATCGCTGAACTAGCTCAAACCATTGAATCTACTTGTGAAACTGATTCTACTGTCAGTACCAATGAAATTACTCCCTTAAACTTACAGGCTGAAGTCGTCCTTGATGAGACAATCAAGCCTTTTAACCTAGTTTATCAACCTGTAAGTGAACCAAAGGCTATTCTGCTCACGGGTGCAACAGGCTTTATTGGTGCTTTCTTGCTGGCGGAATTATTACAACAAACTCAAGCAGATATTTATTGTTTGGTGCGTGCTGCTAACTTGAGCGCAGGTAAACAACGCCTCCAAGAAACCCTGAAAGCTTATTTACTTTGGGAAGAATCTTTTAACTCGCGGATTATTCCAGTATTAGGAGATTTATTTCAACCGCTTCTGGGTCTTGGTGATGAGCAGTTTCACTTCATGGCGAGGAAAATTGACTTAATTTACCATAATGGCGCTTTGGTAAATCATGTTTATCCATACGCTTTGTTGAAAGCAGCAAATGTTGGTGGAACTGAGGAAGTCTTGAGATTAGCTAGTCAAATCAAAATCAAACCTGTGCATTTCATTTCTACTGTTAGCGTTTTCGCCTCAGATGAGTATTTCAAATTAGACGTTGTTCAAGAAAATGATCCTCTGGAACACAGTCAAGGACTTCTTGGAGGCTATACCCAAAGTAAATGGGTGGCAGAAAAGATTGTCATGATGGCACGCGATCGCGGTTTGCCTTGCAGTATCTACAGGCTTGGTAGAATAACATGGCACAGTCAAACCGGTGCTTGGAATTCAAATGATATGTTTTACAGATTCATCAAAAGCTGCATTCAACTAAAAAGTGCGCCAGAGATGAACAGCACGGTAGAAATTACACCTGTAGACTATCTCACCAAAGCTTTAATCCACCTGTCGCAGCAGCCAGAATCTTTGGGCAAAGCCTTTCATCTAATTAATTCCGATTCTGCTCCTTGGAGTCAATTTATTAACTGCATCCGCTCTTTGGGCTACCCTCTGCAACAGCTTCCCTATGAGGATTGGCAAGCTGAACTACTTCGCAATACCCAAATTTCTGCTGATAACGCTTTGTATTCAGCTATATCGCTAGCTGAAGACAATACATCTTCAGAGTCCAATGCAACATCTAGCTTAAAATTTGATTGCCAAAATACCCTCAATGGACTTGCAGATACCACCATTCGCTGGCCGGAAGTAGATGATAAATTACTCCAAGCTTTCTTTGCCAACTTTAGCAATTCGACTTTGGACAAAAAAAAGTAATTTGGGTTTTTTGCATAAATGTGGCTTTGAACATAAGCCTGATAGAGTCGATAGCGGTATTGGGGTAAGCTTTGAGCGTCACTGCTCTCCCCATCCTGCTGTCATATAATGTCCGGCAACTTCGTATGATATGATATGTCATTGCGAACACTTCGTACCCTGTAAGAACGCTAAGGGCGGTACGCAATGACAATTATTTAACTGGACATGATATCAGTTGAGCGATCGCACAAATAAACCACCTTCATGCAATGGTGCTGTATATTTTATTTTCTGGAAGTCCCTTAGTATTAATTCCACTTTTAACTATAAGAGTGTGAACTCTAAGGTAGAGGGTGTAAATTCACGCCAATAAATCTTAATACTCTGGTAAAAGATAGAGTGGTAGGTTTTTTACAGTTTATCTATCGATAGGTACTGGATAAAAATTTCTAAGTAGTCTTACTTCCTCGTTGCAAGGACAAGGAAGAGTTCCCCGCCGCAGTACTTCTTACGGTGGAAAGCCTTCTATTCTTTTTCCTGTCATTCTTTCCTCATTTCTCTGTTCCCTTGCGTCCATCGCTTTTCTCTCTTTTGAGTAATGATAAAGACTCTACGCTCCCTTTTTTCTTACGCAGCTTTAACTACTATTGCTTTGGTAGCTGTAGTCACAACCCAGTTAGTAACTACCCAAAAAACTCCTGCGATCGCTAACATTACACCTACCGTTATTCATTCGTTTAATAGCAGTAACAAGTCCGACGGTTCGACTTCAGAGGCAGAATCTGTACAAAACAGCGATCGTAACCTTTACGGTACGAGGTACGGGGGAGGCGCAAATGATAAAGACCTGATTTTTAGGGTTCCTCCTAATGATAGTAATTTCAACCTTTTCTATTTGTTTAGGGATAAGGATGGTCAAAGGACTAATTCTAAAATTGCGGCTACGAGCTTGTACGTCTATGTATCTCCCACGGGAAGCGACACCGGAGGCGATGGCTCGCTAGGCAAGCCATTGAGGACGTTGGCCTATGCAGCAAAACGAGTTCAACCGAATCAAAACTACACGATTTACCTGAACGCAGGTGTCTATAGGGAAACGGAAGCGACGGTACTTCCGCCGGGAGTGAATATCGAGGGAGCAGGTGAATCAAGCGTGACTATTACTAGCAACGGTGCGATTCCTGCTCCAGGAATAAACACAGGTAGCACCGACTGGAGTCTTTGGCATTATGGAAGCATTATTCAGCTTGTCTCGCCTAGCTACTCCGGCTCAAGCCCTAGGTACGGGGCTCCTTCTGAAATGGTTGAGGCGACAGACGGCAATCAGACCTTAAGCGGCTTCACCATAGACGGGAACGGCAAGATCATCAAAGCCGGTGTCTGGGTAGAAAATCGTAATAACGTGACTATGCATAATGTCACATTCAAAGATTTCCAGCACAGCGGTGCAGTTTTTACCCGTGGCAATATGTGGTGGTTCGTCCCGCTTCCAGAGGGAAAGTGGATGAAGAACACAACGATACATGATTGCACGTTTATTAACTCCGCAGCTGATGGAGTATCGGGAGGATCTACTGGTAACTTGAGACTTGGGGGACTTGATGGCGCTGACATCTACAACATTACTATCCGAGAAAATAAAGGATACGGCATCAAGTTCATACATGTAGGTCATCTGCGTAACGTGAAGATTCACGATTGCGATATCCAGGTTCCAGAAGTTGATTCCCAGTGGAGCGAGGATGCTTCCATTGAACTTTGGAATTTGAGTTATGGAAACGAAATCTACAACGTTACCTGTAATACGTGGTTATCGATGGTTAATCATGCAGTAATGAATGATTACCAGCCGACAGCTACACACCCAAGCAATCTCAAGATGCGAAACGTAAGAATAAAAGATATTGACGGACAGAGTGTTAAGGAGTCAATCGAGGTTGCCTTGAGTGGAGTTGAAATATCCGACTCCTATTTTCAGGATAAGGGCTTTGGTATTGCGATCTGGGGAGGGAAAGCATGGGGCGGAAGTATAGAAAATCACAACATCAACATCCACAATAATATTTTCGCAAATGTTGCTCGTAAAGTTCAATTTGGTTTCGGGAACAGTACTGCCGTCTTCATTCCCGATTTAGCTACCAACATCAAGATTCACAACAACGTGTTCGATACCTTGGGGAATAGCCTACAGCTCAACTCCGCAGACAAGATATCGATCAAAAATAATGTGTTCTTGAACTCTCAAGGAGACGATGTGCAAGGAGGTAATAACATTGCTTTCACTAATAATCTCCGCAGGAATACGAACCCAGCAAAACCAACTTGGCAGATCCGATTCGCGGCTAATGCGACAAACATTCAGGGCGATCCCAGATTTACAGGTACAGGCGACCGTTGGAACTCTTACTACAAGGCAGCTTCGTCACGCAGTCTTATGGTGGATAGAGGAACTAATGTAGGACTTCCTTACTCTGGTTCGGCACCTGACATCGGTCGATGGGAGTGGTAAAAATACTTGTTGGGTTTAGGGGGAAAGGGAAAAGCTTAAAAGGGAAAAAACCTTATATATCGAGTCTTCCACTCCTTTTTCCTTTTAACCGAGCAGTATTGGGAGTGGTAAGGAAAGTTGATTTAATAAAATCCAAATTTTTGGATCGGAGTTTGGCTATACCAAAGCCTTAAAGGATAATGTACAGTGACAAATTAATGTCATCGAGGGTGTGAAAGCTTGAACTCTCTAGTCTTAAGCTTAGAAACGGCACAGGGAACTTACAAGCTGTATCAACACAAATTGTTGTCAGTCTAAAGTGGATAAGGATTTATTTGATGACACGAATTTGTCTCAACATCATTTAATTTTTCACTGTACAAAAAGGGAAAAAACCGCGAAATATTGTGTTTCACGGTTTTTAGTGTGGTGTAAGGAGCTTAACTAAATCTCATCATAAAGTAACAGCTCAACAGCAACGCACTGGTAACAATTTTGGTAACAGACTTTTTTTAGCAGCCTTAGAGCAAAGCACCACCACAACTAGAACCACACCCAGCAGTACAACCATAGCAATAAGCAGCAGTTTGGATCTCACTAATCAGGTCTAGACTGCCAGCTTCTAGCAATTTGCTAACTGTTAGTGGTTCAGAATTACCAGTTTTTGCAGGCAAATTCATCATCTGGTTAAAGTCACAATCATATACATTTCCTAGATAGTCAATTGAAAGTTGATCGCGGCACATCAAATGTTCAACTGTGCCAGGATTAAAATTTGACTCTAAAAACTGCAAATAGCTACTGTGTAGTTTTCTCCGTTCTAAATGTATTTTGGTTCTACCAACTGGTAGGTTGTTAATGGTGAAGAGGTTGTTAAATACAATATTAAAATGTTCTTGTAAGAACGTTTTGTAATCTCGTTCTAGGTTAGTCTGTTCGGGAGCTAAGGAAAATTTTTCAGTAGTGGGTAACTGGGGATTAAATACCAAGTCCAAAATTAAATTTTCATCTTTACCATAGCCGAGTTGGTTAAGCCACTGCAAAGCTTTGACTGAACTATCAAAAACGCCAGAACCACGCATTTTATCAACATTATCTACTAAATAGCATGGTAGAGAAGCCACAACTCTTATTTGGTGTTGAGCAAAATATTCTGGTAAATCAGCAAATCCATCTTCAAAATAAATAGTCAAATTAGACCGGACAATCACCTGCTTGCCGGTTGCTCTTGCTGCTTCTACTAATGGCTTAAATCCATAATTCATTTCTGGTGCGCCACCAGTCAAATCCACAATTTTAATTTCGGGAAATTTATGGATTAGCGAAATCAATTGTTCGCAAACTTCAGGAGAAAGCTCTTCTGTACGTTTTGGCCCAGCTTCGACATGACAGTGTGTACAGGCAAGGTTACAACGCTTACCTAGATTAATTTGTAAAACAGAGATCCCCTTTTTTGTCAAAGGTGAATTTAGTTTATTTTTAAATGGTGTAATTTTGGATTGAGTTTGCATTAGCTACTATTCCTTAAATATGATAAAAATTTATTAAATTTTTCTAACCTTGTAATAATCTGTAAATTATTCCACTAATAATTGCAGCAATAGGTAAAGTTAAAATCCACGATAATAGTATCTGATAAAATACACGCATATTGGCTTTTTTGCCAATCAAACCGACTCCAAAAATAGATCCAACTGAAACATGAGTGGTGGAAACAGGAAGTCCAAACAGACTAGCTGCAATCACTAGAATTCCAGTTACTATATTTGCTGATAAGCCTTGAGGAGGATTCAATGAGGTAATCTTTTCACTCATGGTGACAGCAACTTTTTGGGAGTTGAGTAAACCGCCAAGTGCCATTGCGATCGCAATCGTGATCATTCCTCCCTGAACCGAAAAATACTCAATAACTAGAATGAGTGAGGAAATCTTGGGAGTATCATTTAATCCTCTCGCAAAACTCACAACTCCGGCGCTGAGAAAATGGCAAGTATCAATCATTTTTTGATTGACTGGTAGGTTCCATTTGGAATTTATATAGCCAGATAAGCTGTAAATTGCTGCTCCGAAAGGAATGGCAATGATCGGACTGAGAAATAAAGGCAAAACAAAGGAAGTTCCCAAAACGGCAAAATTGACTTTGAGTCCGATCGCAACTAATCCAGCGCCAACTAGCGCACCGATTAAACTGTGAGTTGTGGAAATGGGAAACCCCATAAGGGTGGCTATCAGTACAGTTAGACCAGTTGCGATCGCAACTGCGAGATGAAACTCTGGTGAATTAGCGATCGCATCAGGCACTAGTCCTTTACCAGAGAAGTTTTTAATTAGTGTACTTGCCAAAAAAGTTGCAGTTGCTGCACCACCTAAAGTTGTGAAAGTTGCCCACAAAATTGCTGTTTGATAGCTACTAGTTCGGCTACCAAACAACGTTGCTACCCCTTTAAAGTTGTCATTGGCACCATTTGAATATGCTAAAAAAAGCGTAGCGATAAATAAACTAATTAACAACATTTTGGGGTTTATAAATAAGAAGTCAGAATCCAGAATCCAGAATTAAGAATGCAATTTTTAAAATATTCTAATTATACATTCATACCCCAGTCGTACAGAATAATTCTGAATTCTGTCTTAAGAAATTAACAGCAACCACCACCGCTATAGTGCCAGGTTGAGTTGGTAACAATTATTTCTGCTGGCTTGATAGCCGCAAGTTTAGCGGCAGTTTTATCACACACTGCTGCGGGAATACCTCGCTGGAGTAAGTGTCCTGCTGAGTCATCGAAAAAGGGTTCTGAACCAGCATAAATTGCTGTTTTTCCTGTGAAAATACAAGCACCATCTTCTGGAATATCAACTTTAAAGGAGACAGAATCCAGGCTTTCTAAAAGTAGGTGTTCGTCTAAATTATAAGTCTGAGAATCTAGTAGACGATAAGGACGACGAGCGCGAATTTCAACTTGACCAAAACCAGCATTTGTAATCAGTTCAGTATACTCTTGATATGTAAGCGCGCCTGATAAACACATGGCTCTGAGTCGTTCATCTTGTTGAAGATGTGCTGGAATTTCACTAGTGGCAATTGGATCGCTCATCTGCAAACGTCCGCCTGGTTTTAATACCCGATAGGCTTCTTTTAAAGCACGGTTTAAATCTTCTGGTTCAAAGATGTTGAAAAGGCAATTCTGCGCCACGATATCGACGCTAGCATCAGCAACCGGTAAGTTAAAAGCATCACCTTCGCGGATTTCTACAAAACTCGTGTCAAACCACGGGTTTTCTTGAGCAGCAATTTCCAGATTGCGTGCGGCTGCTTCCCGCATGGCCCCAACCGGTTCAACGGCAATTACAGCACCTGCATAGCGGGAAAAATAAGCGAATTGCAACGCTTCTAAGCCGCCACCAACGCCCACATAAAGCACAGTAGGCTGATTTCCTAGTTCGCTGGAGTGAACGGTAGTGCCACAACCATAGTTCATTTCCTGCATAGCCAAAGGAATTTTCAACCCTGGTAGTTGCAGGGGTGTACTTTGCACACAACAAAGTCCAACTTGCGGGGTTTCGGCAACTTCGCGGTAAAATTGCGCTGCTGTTTCTAGATAAGTCATGCAGTTTTAGATTTTTAGATGATGACAGCTTTGTGCATCCTAATATAATTAACCCTGAGTTGGATGAGTTATTGCTCAGATTGCCAAAAACCTCAAATCTTCCTAGAACACAAAACTTTGAGGTTTTATCGTTATTTCACACTGGATAGGGGATGAGGGAGCAGGGAGCAGGGGGACAAGGGGACAAAAGTTTAGAACTTACAACAAGTCTTTCCCCTTGTCCCCAATTCTCCTTGTCCCCAAGTCCTCTTTCCCATCTCAAATTCAATCATGCAATGTGTAGCCGACACCACTCACAGTTTGAATGAGACACTTTTCGTTATTGGCTTCAAGTTTCAGACGCAGGTAGCGTATATGAAGTTCGATGATGTTGGCATCGCTCATGAAGTCGTAAGCCCAGACTTCTTGTAAAATGCGATCGCAGGTAATTAGCTGTCGTGGATGGGCCAGTAAATATTCCAGTAAATCAAATTCCTTAGCAGTTAACTCAATTAACCTTTGATCTCGGTACACTTGGCGCGTGCGACGATTTAAACTCAAGTCTTCAAATTCTAAAACATCTGCGCTGTCTACTTGCCAATTTCTTCGCAGGTGAGTGCCAACTCTGGCCAATAATTCATCAACACTGAAGGGCTTAACGAGGTAATCATCAGCACCAGCGTCTAAGCCTACAATGCGATCGCTTACTTCATCTTTGACGGTTAATAATATTATTGGCAATTTATCACTAATATTTCGCAGGTGGTGGCAAATCTCTAACCCCGATAAGCCAGGCAACACCCAGTCTACAATTACTAAATCTAGATGTAACTCACGCGCTGCGGTGAGTGCAGTTAATCCATCGTAGGCAATACTGACTTGATAGCCTTCATAATTTAATTCTAATTCGACAAATCGCGCCAGTTTGACTTCATCTTCAACCAGTAAGATGTGCGTCATGATGATGTTAATGATTTCAGCAGGGTACGGTAAGCAACAATACGGTCTGGAAACACTTGAGCGAGGTGCTAGCTACTTACATAGCAAAACATCTAAATTAGGTGTACGTTAGCTTAGTATAAACCTGAGTAAGTAACAACAGTATATTTGAAAATACCGATGGCTGCTTAATCAACGAACGATCAAACTGACTATTAGCAATAGCTTGTGACATCTTCACCACATTTATCGGCAAGATAACAGAGTGCTTTAAAACGCAAACCAACTACTTCCTCGTATAGTGGATTTAATTTACACATCGGAGGAATATGAAATAGCTTCCGACCAAACAGTGTGATATCTTGCTCAAAGGGACACTGAGCAGGAATAGCTTTGCACAAGAAATGAGCCAATTTAGAGTTATGAATTTCTATCTTTTCCAACCACTCGCGTACTGGGTGTAGTAAATCATTGTGTGACCGTACTTGAATAAAGCTTGTCATAATTTTTCACCTTAATAATTTCAAACTAGATTGAGTTTGTTCTATTTGAACCTCTATAAATACATACACTTAGGTTCTATAGTTTTATGCACTGATTCCTAGTTCGTTCGTCCTCTACAAAGATAGAATGAATCTCTAGGTACACTGTAAACTACACATTCAAGGGTCAAAATTCCTGATGATTTCTACAATTTCCAAAAACTTTTGCAACAAATGAATCGGCTAAAGCTGTATCTCACTGGGGCAAGAACCGCTATATTGTGCCAAACGCTAGGCTAGATATTGCCGAACTGCAAAACTATAAATAAATTCTGGGAGGCGCAGCTAAACTTACTCTAAAAAAGCATCAAGCTTTAAGGAAGCTGCGAAAACTTATGACTGATAACTTCTTCAGTAACAAAAAGCTACTTTTTGACCGATGGGCACCAAGTTATGATTGGCTCTTTCCTTCAGTGTTTTATCGAGCCATTCACAAACGCTTGCTGGAGTACGTCGATTTACCAAAGTCAGCAAATGTACTTGATATCGGTTGTGGTACTGGCCGCTTACTTGAGCGCCTTGCTACTCAGTTTCCTGACCTGCGGGGTACTGGATTGGATTTCTCTGCTAATATGTTGCGGTTAGCAAGACAGAGCAACCACCACCGTCCACGCTTAATTTATATTGAGGGTAAAGCTGAGTCTCTTCCTTTTGCTGATGGTCAATTTAATGCTGTCTTCAGCACTATCAGCTTCTTGCACTATTTGGAACCGAAACAGGTAGTTAGTCAGATAGCACGGGTACTTTCTCCCGGTGGCCGTTTCTACTTAGTTGACATTAACATTACTTCTAAAAAAGAGGCAGAGCCTCAATTATTGCCACTTACTCCCCGTGGAATTAGACTCTACAGCCCTAATCAACGTCAACTTCTTGGCTCTTCTGCTGGGCTATTGTGTTTGAATCACCACTATTTATTAGGGCCAGTCTTACTAACAATTTTTGCTAAACCTCCGATTTGAAAATAGAAAATTGGAAAGAGTAAAAGATTGTAAACAGCTTGTATCAGTCATTTTTCTCTATATCTTAATTACGAATTACGTTAGCGTAGCGGTAGCGAGTCCGCGAGCGTCATTACGAATTAGTATGTCCTCGATATTCCATAAACACCACAGGAACTTTGAGCAGCTTTTTAGCTAATTGCGACAATCTAAATTTATCGTTGAGCGTAGACAAGCCTGTTGTTCTGGGAAATTGTGGCAAGTCTTCAAAAGATATTGGTGCAAAATTAAACCGACTGTAAAACTGTGCCAATCGTTCACCTAAACATTCAAGATAAAGTGGTTGCGTTGCTGTATTAATCAAATGCTGCGTTAGCAAAGTACCCAAACCGCGACCTCTCCAAGCTGATGCAACGACCAAACTACCAAGTTCTTGTGCCCCTGAAAAATTACGTAGCTGTCCGCAAGCTACGAGATTATCACCAAATTCAATTACCCAAAATTGCTGCCAGTTTAATTGAGTTGGGTCGAGTTTCGCTGAGAATACCAGCAATCGAATTGACCACTTATCCGCCAAGGTTGCCTTGCGAAGGACACATCCAGATGGTAACGGTGGATTACTCTGGTTCATTAATTACACTTTGATAGTTTGGATCACAATCATCACACGATATTATTCACTTAGATCATTTGCCATTCTCTGTCAAGTGTCAATAAAGCAATTCTAAAAGCATCTCGGATATCAAATCTGTTCTAAATTGTCCTTTAACGACGTCAAGCATTCTAAGGTTAGCAAATTCTATAGTTATGGATTTTTGTCATCAAAGATGAGTAGTACTAAACAATACTTCCGATAGAGGGACAATCAGCGATAACTAGATTCTGGATAGATGTATTCAAAACCCAAATTTTCTTAAGATAATCCCAAGAATAAATAATTAAGGAATGTCATCATGGCTGAACAAAAAAAACAAAAATCTGATAATCAAGAAACTACGCCTACTGCTTCTGGTGGCTACCAAACCCCCATCGACGAAAGTATCCGCAAAACTGGCGATGCTGAAAAGAGTGATGCTAAACCCAGTGCTACACCAGAAGCACCAGGAGAGGATGGTATAGCAGGTAGCCCTAATCAGGGAACTGAATCACGTTAATTGGTTTTAACTTTCCCAAGTTTGAATAATCTTCTTGGGGTTTTTTAGTAACCCCGATTTACTAAACTTTGAGTGGATAGTTGTGGTTTATATCACGATTATTCACTCATTTTTGTTGTGCGAGAATGTGGTGCGCTAAGTGCGTAAGCGCAGCCCCAATACTGCTCGGTTAATGGACTTCTAAATAAAAAAATACTCAACTACTTATTGTGGGGTGGACATCTTGTGCGCCCTTGGCTATGGGCGCACAAGATGTCCATCCCACAGGATTGGATAATTTATTTCTTGGAAGTCCCAACAAAGCTCTGAAAATGTTGGGTTTCGTTCCTCAATCCAACCTACCTGGAGTAGTTTTGCATTCTGGCATTGTTATGTATTTTATTTTACCTCTTACTAAAAAAATGATTTTTATTCACTTAGTTAGTGCTTGTGCAAAGCTATACCCTGTAGGGCAATTCGTGAATTGCCCCTATGGTAAATCGGGGCTTTCACTGCTTTTTTGCCTACCGAAGTTTGTCAGCACAGTGCTAAGGGAAAATCACCTATGCCTGAAAATCTGCTCAACTTCATGATTCTTAATCATGCCAGCTTCCTCTAGTGGCTGACAGAAGTCCCACAATCCAATAGGCTGATCTTAAAGTGGTGATTTTTCACTGAGTCGTTAAGAACTACCTATACAGAAAATGTCTCTTAAAATAGTCCAGAACTTTGATGGCAGTTTCACTCTTGAAGCACAAGCCCAAGAAACTTTGTTCAACTTATTGACAAGCGATGCTTTCTTAAATCAAATTCGTCAACAATTGCAGTGTGAGCAAATTAAATTTACAGAATTAATTTTCCAACCAGTTCCTTATAGCTTAACTACAACTAAAGGAATGCCAGCAGAGTTTGAAAAGTATCATGAATCTGATGAATATGCCATCATCAATGTACCACCAAATTTCATGTTTAGTGCTAAGATTTTTAAACCCAGTCGCCTTTGTGCAATTTACCAAAAATTAGGTAATGGGTAATTTTAAAGATAATTTTTCCCTAATTAGCAATTTTCCATTCTGAAGGCAAATAGTAAGTTTAATATTTGATGTATGGCTCTTGAAACGAATCTTTCTTCTTTGGCAGCCCTGGAATACATTCCTTACATTGATGATAGCGGTCAATTACCTGAGCAATTTCAAGGTAAAATCGGGGTATACGCTATTTTTGACCAAGAAAAAGTGCTGCAATTTGTAGGATACTCTCGTGATGTTTATCTCAGCCTCAAGCAGCATTTAGTCCGTCAGCCACAGCAATGCTATTGGGTCAAAGTTCAAACTATTGAACGCCCTAGTCGCACAATTTTAGAAAATACTGAAAATGCTTGGATTGCTGAAAATGGCAGTGTACCTTGGGGAAATGGGGATAACAAGGAAAAATGGACTCATCCCATTGATGTCAAATTGATAATGACACCTGAAGAACAGGCAAAATATCAAAATCCAGCTAATGATGAATTAGCACAAATGAAAATTATTAAAAACGTGGCGCGGAGAGTAGAAGCAGAAATTTCAACGCAATTATTAGAAGTGCGTGGTTTGCAAATGCAAGTTCGCTTCAATCCTAAATTGAAAGAAGAAGGTTTACTAGATTTGAAATGAAGGTTGTTTTGGGAAAACTATCTTATGAATATCGCTTATAATCTCCCATGACAATACAGCTTCTGAACGATCGCTATCAAGTTATCCGCACACTGGGCGCTGGTGGGTTTGGTGAAACCTATCTAGCAGAAGATACCTATATGCCCTCAAAGCGCCATTGTGTGGTTAAACAGTTAAGACCAATTCACAATAATCCCCAAATTTACCAGTTAGTGCAAGAGAGGTTTCAACGGGAAGCAGCTATTCTCGAAGAACTCGGTGGTGCAAATGACCAAATTCCAGCATTGTATGCCTATTTTTCCTCTGGCGGACAATTTTACTTAGTTCAGGAGTGGGTTGAAGGCGATACCCTAACTGGAAGAGTTCAAAAGCAGGGGCTATTTAGTGAAGGCGCTGTCCAGGAATTATTCATGAATTTATTACCCGTCCTGGATTATGTTCACTCTAAGCACATCGTTCACCGCGATATTAAACCGGATAACATCATTGTGCGTCATCGTGATGGTAAACCAGTGCTGATTGATTTTGGCGCTATCCGGGAGTCAATGGGAACCGTAGTAAATTCTCAAGGCAATCCTACCAGTTCGATTGTGATTGGTACACCTGGCTATATGCCGAGTGAACAAGCCGCAGGTAGGCCAGTTTATTCGAGTGATTTATACAGTTTAGGAATGACGATAATTTATTTACTCACTGGTAAACAGGCGCAACAACTAGAGACGGATTCCCAGACGGGTGAAATTGTATGGCGACAGTATGCGAGTCATGTTAGTCCAATCATAGCAGGAGCGATTGATAAAGCGATCGCATATCATCCGCGCGATCGCTACCCCACAGCTAGAGCAATGCTGGATACTTTGCAGAACATCGCAAATCCAATTCCACCAACGCAACCTATCTTGACTCAACCGACTATAGTTTCTGCACCACCACCTCAGACATTACCTGTCAAACCACAGCCGAATCCTCAAGGTAATAGTCAGAATAATATCCTTATGGGCAGTTTGATTGCAGGTGGGCTAATCGGTGCATCTGTGATTATTAGCCAGGTATTAACAAAACCTACTCAATCTACAGCAGACAAAACAGTGTTACCTTCAGAAACACCGTCAACTATCACCAGCCCAGTCATAGAAACTCCTAAATTTATACCAACTACCCCATCTGTTCCTACTCAACCCTCATCTGTTCCTACTCAAATTACACCCGCCCCAACGACATCAATACCGCCAGTAAGTACCACAACTGCCAACACTTATTTATGGCTTTCCCAAAGACTTGTAAATGATGCAGATTTGGATGGTAAAGACGGTTTTGAACTAGATATTATGCGAAATTCGATTTTTGCTAGTCACGGCCGCCGTTTTGATACTCCTGGATTACAAGATTACTTTGATAACCAACCTTGGTATAAACCTATATATTCACCAAAAGCGTTTCCATCTAAATTGCTGTCAAAATTAGAGCAACAGAATATTGAGTATATCAACAAATATCAAGAACGTTACGGCTTGAGATATTTTAAGAAATAAGTTTAGGCAAGAGGTAACTGGAAAGAAAGCTTTTTGAATTGTAATGAGTTTTTTCAAAAATCAATCAAATATGAGCCTTATATGTTGCTAGGGTCGTACTAGTGTAAGCGGTTACACTCGATACATTTATTGCAAATATTCTTGTAAATGCTATAACTTCTAAGTATATTAGCTTGAACTTATCAAAGGATTTATTGCTACTTATTAGATAATATCTAGGTTGTCTGGTGTAATATACTAGACTTATGACTAGATATTTAATAGCCTAAAATCGCTAGATATTAAAGACTAGTCCTACCGAAGCCTATATGGAGTGAGAGCTAAACTGTTTTTTTCTACGCCAAATTCCATCTCTAGATACTAGGCCGTTTCAGAACCAGGCATTTATATTTAATATATAAAATTGCTATCTCAAACATTAGCAATCGATAAGTTAAAGAAATGCCATTTTTATAATTTCTTTGTTATTTTGTATTTAACGGGACAGTTCTTCCCGATTTGGTGGGCTTAAATAACAATTAGTTAGACAATTTCCCTCCAAAGATGCATGTAAATTCTTTGCGTTGTGCTTATTTTTCTGCATAATCTCCAAGCATAATGCAAATTGGCTCGACAGATTAGATGTGTAATATTCCAATTCGGCAAATAGTTCATCTACACAAGGAAAACCTTGCCTACTACTATGCTTAATATAAAGAATCAGCGTATTTTTTTGCCTGCGTTTATTCAACCTTTAGGACAAAATAATCAAGCAGATAGCAAAAAGGAATTAGCTAAATCTAAATTAGATTTATTGCAACCATTACGTCAATGGCTGGATGAAATTGAGATTCAAAATCGAAAATTAGCGAAATTTATTGCTAAACTGATTCCTGCTCAGTGTCCATTCGAGCGTGATATCAAGCTTTTTGGCCGCAAAATAGGACACATTCCGCCAATGTGCAAACTCAATCCGCTTTATAACGAACTTGTCTACTTGCGTTTTCGCGCTTTGTGTTATTTAGTAGATCAGTGTGGAGAGGATATTCAATCCTACTGCTGAACATAACTAGAAAAACGCAACATGGAAATTCAAATTGAGCATCAGCTATAAGACTTGAACGCCTCAATGAATTGGGTGTCTATAAATGGGATATTTGGAGAAAGGAAGTCTCAAAATTCCCTTGGACTTATGATTCTCAAGAAACTTGCTACTTTTGGAAGGCGATGTGGTTGTTACTCCTGATGGTAGACAACCAGTGCAAATGGGTAAAGGCGATTTGGTGATTTTTCCGGCTGGAATGTCCTGCACCTGGGAAATTACAAGCGACGTGAAAAAACATTATTACTTTGATTAATCAAGACTTAAGATTGATCCCCGTTCTTTTCTTGATGATCCACAAAACCAACATCTCACAACATCTCATAAATTTAGATTTTTCTTATAGGTGGGGTTCGCAATGAGAATCGTAGGATAAAGTAGCATATTTGGTAAATTGCTTATATCCATATCTGTCAAAACTCGTTGCGACTCCATCCCCTAAACAATATTTATAAAAATAGATAGCCTCATTTTCTCCATATTTGGCAGAAAGTTGATGGCAGATATCTAAAAGTATGAAATTCATTGATCCCCGACAATTTTAGCGAAGTCGGGGATCTTGTTCTTGAAATTTATCATAGCGATCGCCACTACTGGGAATCTTGGGAGTTCATAATCAAGTTAGTGGGAGTTTAATCAATACTTTTCGGATAAACCCAATAATCTCTCTTTTGGTCTGGGGAAAGGTTAAAGGGCAATGGGGAAAGGGAAATTCAAACCCTTTCCCTTTCCCCTTTTCCCCAAAACCCGAAAAGTATTGAGATGCTATTCAGCAGAGAAGGGTTTCGTCTTACCGCAATTTTATTGAGGAAAATCATTAAAAATGTTACTGCATTTGAGTACTTGGCAAGAAGTCGAAGCTTATTTACAGCAGTCGAAGGGGATTATTTTCCCTATTGGTTCTACAGAACAACATGGGCCAACGGGGTTAATTGGTACTGATGCCATTTGTGCAGAAGCGATCGCAGCTGGTGTGGGTGATGCAACTGGCGCGATCGTTGGCCCTACAATCAATGTGGGCATGGCACTGCATCATACTGCTTTTCCTGGCACAATCAGTCTGCGTCCTAGCACTTTAATTCAAGTAGTTCGAGATTATGTAACTTGTTTAGCCAAAGCTGGTTTTAGCAAGTTCTACTTTATCAATGGACATGGTGGTAATATTGCCACCCTTAAAGCGGCGTTCTCCGAAACTTATGCCCATTTAGAAGATTTGCAGATTGCCAATGCTCAACAAGTGCAATGTCAAGTGGCAAACTGGTTTATGTGTGGTTCTGTATATAAGCTAGCTAAAGAGTTATATGGGGATCAAGAAGGTTCTCATGCAACGCCAAGTGAAGTAGCCCTCACCCAATACGTTTATCCAGAAGCGATTAAGCAAGCACCCCTTTCACCAGAAGTTGCAAGCGGACACAGGATTTATAGTGCGGCTGACTTTCGAGTGCGTTATCCAGATGGACGTATGGGATCAAATCCTGGTTTAGCAACACCAGAACACGGAAAGCAATTTTATGATTTGGCGGTGAAAGAACTCAGCAATGGATATTTGGAATTTGTGAACGCAGATTGAAGGGGGCAGGAGGCAAGGGGGCAGAAAGTAGAAACTCTATCTAATGTGTGAGTCCTGCATTTGTACTCTTTCCCTTTCCCCTTTCCCCTTTCCCCCTTAACCAAAAAGTATTGGGGCTACGCCTACGCACTAATTCCTACAAGCTCAAAATTTATTTTTTAATTGCCGCAATTGCCACATTTTCCAGAAATAGCTAGAAATCCAATTGGTAATCATGTGAGCGACAATCGGCACTAATAGGTTGCCCGTAAGCAAGGCGCTATATGCCAATATCATCCCAACAATTGTTGCCCAAATCACATAAGGCCATTGTTGAGAACCACTAAAATGCAAGATGCCAAAGCAAAAACTAGATACAATGACAGCCAGATGATCTAATCCTAAAGCTGACAGCATTACACCTCGAAATAACAATTCTTCACTCAACCCTGGTAGTAAACCGAGCCAAATTAAGTCTGGTAAGGCTAAGGGCTTCAGTACCACTTCTAGATAATAATCTGCACTTTTTCGATAGGGAGTCCAAACGCGATAAGCTATGCCACTTAAGGCGGTGATGACGAATCCCAATCCAACACCCAACAGCAAATCTTTCTCGTCCCACTTCCAGGAAAATAGGGAAAAGTTACCAAAGTGCAACGACAGTTTGGCGACTATCAACAAAATGATTGCAGTCGCTCCCATCGCCCCAAGTACTTGGATGCGTGTCAGATATGGAATTTCTGGCTCTTGTTTTTGTTGTTCAATCACAGGTTTTTAGGGGAAGGGGCAGGGGGAAGCGGGCAGGGGGAAGATAGAACTCTAACTCTTGTACAGACGCGATTAATCGCGTCTCTCCTAACTCCTAACTTTTAATTACTGGCTGCAAAGGTGATAGTTTGGGACGGAGAGCGGAGGGGTTAATGCCTGCTTTGTGTGCTACTAATACGCCTACTGCTTCTAAATATGAGTTTACCTGTATAACTTTGATCCCCAACGGTTGAGGAGGAACTTTGATTAGAGTTTTATTTTCTTCTACTGTAATTATTTGGCATTGTCTTTGGCTTAAACTCAGTAAGGCACTGCTACCACAAGCATTTGCAGGTGCGATCGCAGCATCCACTTCATCTGCCCAAATATCTCCTTTTTCTGATGCAATCGCTCCTTTATCTATTATAAATTGTGGGGCACGACTTAATCCTACAAGGACGCACGGCAAAAAGGTATAACCCAATTCTTCGGCGGCGGAACGGGGAGATAAATCAGCTTGTGGGGGTTCGCTCAAAAGGGCGGGAGAATGGGCGCAAGGAATTTGAAAGGTTCGCACTAGCAAATGGCTAATTACGGCTTCTGCACCCGCTAGGGGATCTACGCCTTCACCTTGACGATATTTCTGTACTGCTTCTGAGTCCATATCATCGGGGAAACGGGCAACAACTGCGATCGCTTCTGCCCCCGCTTTTTTAATTAATATCTCGGCTGCCCTTAACAAGCTATCTGGGTTGCCAATTGTTCCCCAACTAGCTCCCGATGCTGTAGTCCGCAATTCTACATTTAATGGTGCATCTGTAATTACATAATCTGTTAGAGTCAATCCCAGAGTTGCTCTGACTGCATCGGCTGCTTGTATATGCCGTAGCCTTAACTCTGGCTCAATAGCTTGGTCTAAAAGCAAACCTACTTTGTTGTTGCGGACTGGACGCAAACCCCACCACCCAGAGGCAAATTTGTCAAGTCCATAACCTTCAACATAGAAAGTATTTGGAAGGTTCCAATACAAACTTGCGCCATTAAGGACATTGGGGTGAGTAATTAGGCGATCGCAAACCTGTGCGATGACTTTGGCAACAGGTAAAGCATCTCCTGCATAACCCCCAATGGCAGCCCCAATGCCAGTTGGTACGATTAAGATAGCGGTGTATGGACGCATATTGAGTTATGAGTTATGAATCAGAAGCCATCAAATACTAACTCCTAACTCTTGTACAGACGCGATTAATTGCGTCTCTAATTCTATTGATCTCATTTTTCTGCTAAAACTATTATTGCTTGGCAAGAAGTGGAAGATTATCCCCAGTTGGAAGACCTTGTAGCCTTGGTTTATGGTTGGGATAAATTGGGAAATGAAACGCTAGAAGATGAAGTGATTGAGCTACTGGGCTTTGAGGATCTGGATGATTTTTGCGATCGCATTACACCTGTAGAAGGAGATAAACTAGGGGGTTATCCAGAATGGGTACAGGGAATGGAATGTCCTGGCTGCCCCATTTGTCAGAAACCTATGCGTCAGGTTTTTCAACTGGCTTCTAAGGATAATATCCCTTATTCGTTTGGAGATATGGGTACTGGACACATTCTTCAGTGCAAGTCACACAAGCATGAGTTTGTCTTTGTTTGGGCTTGCAGCTAGGAAATCTTCATGAGCCTGATTATTAATTTACTATAGGACTCATATTTGATTTTTGAAAAATACAACTCAAAAGCCTTCTTTCCTATTGCCTATTGCCTCATTCAGAAACTATAAGCAACTCATATTTTATATATTATCACTGTTACACTGCCTGCTAACGCAGATAAATAAACCAGATTGTGAAATTGAAATTTTTTCAACTTGCTTCGGAGCTTTTATTTCAGTAAATAACTGAATTCCTTGATTAAAATTAAGTTTACTTTCATCAGGCTTTGCCATCTTTTGATAAGTTAAACCTAATTGATAATAAGCTTCAGCTAGATCGCACTTAGCACCTATTTTATCCAACAGTTCGATTGCTTCTCTATGATGAGCCAGGGCTAATTCAAAATCTGCTTGTTGCCGATTTATTTCTGCTAAACCATTGAGTGTTTTTGCTTTCACCTGCATATAGTGGCTTTCTTCCGCAAAAGTTAAAGCTTGGTGTAATATTTTATTTGCTTGATAAAACTCTCCTAAATTGACGTATGTTTGACCCAAAATTTGCATGAAATAGACAAATCTCCCAGTCTGTTCTACCAGTTTTTCGTTCGTAATATTCTGATAAGCTACATCTGCTAATGCAAAGGAGGCATCACGCAAACCTAAATAAGAATACACCAAAGCTAAACAAACTGATGCTTTCTCTGCCCAGCGATGATGCTCAGTATTTTGGGCTAGGTAAATTACTTGTTGAAATAAATTTGCGGCTGCCTCTAACTCCCATAAATCTATCTTGTAAAGACCAATACTTAATAAAGAATCTACCTCTAGCATCCTCAGATAGTAAACTGGATGTTTATTTTCTGGCTGAGGTATAAGTGATTTTAGTGCTTTGGTTGCCAGAGTAAGAGTCTTTTCTTGACAAGCGATCGCTTGACTAATTTTACCTGTTATCCAATATAGATCGCCCAGTATATTATAGAGTTCGCTGAGGTTTTGGTTATTTTCCAGATTGTTAACAACTTGATTAATTGCCGCCAGTATCGGTTGAATTAAACCCATCCGATACAACGTACTACCAAGAGGCAAAAATTGCTGCCATTGATTATTTCGGCTTTTTAAAATTACCTTACCTGCGAACTCAAACTCATTAATTTCTATATAATGATAATATGCTTCGAGAGCTTGCAAAGCATCTTTAAAAGTTTCAATTTGTTTAATACTAGCTGTCCAAAATTCTGCGGCTTTGTGGTTGGCAATTTCCCATTCATTGCTGGGGCGTAAACGTGCGATCGCTTCAGCACGAATCACCGGATGCAGCCAATATTCGCCTTTATCGCACTCCACTAAAGACCGATTTCTCAAGGAGGCGATGATTTGGCGATGTTGATCGGGTGGGACATCCCAAAGTAAACAAAATAACCCTTGTGATGGGATGGTGGGTATATCTTGGTAACGATAACATCCCAAACGGCAAAGCAAGCGATAAGCTTGAGGGTCGAGGGCTTGCAAACGATTGATTTGACTAACCGCTAAATTTTTTAAGTCCGTTGCTGCTAAAGGATCGGCATGATTTTCTTGCCAATAAAGAACCATGTCACCGCCAAAATCTTCCTGAATCGAACCACAGAGAATTCCCATTGCTTTAGCATTACCGCCATAAGTGCGATGTATGATTTGCAAGGTTGGCGAGTCGATGACTAACCCACGGTTGCTAAAAAACTTTTGCCATGCGCTTTGATCCAAACCAGGAAGCCGATAGTGATTTACATTCAACCCAGGTTCACAAAGGCGATCGCGGCTAGTAATCAAGGTAACAGATTGCACCCTGGCATCAGCCAACACCCGCAATAGTTCTACATAGTTGCGGTGAGAAGCAATCAATCCACCTTGTTGATCTAATGCAGGTTCGAGATTGTCAATTAATACCCCAATCCGCCGATTGTGGAGTTCGCGCTTGAGTCGTCCCAATGTAACCCCAAATTCTACTCCAGGTTCTTGCTCAAAGTCTTGTTTGAGCCATTCTTCTACTACTCGTTCGGCGGGGGTGATGTTTTGAGTTTCCTTCGCCATCAGCAGTTCCAAAACCAAGTCAAATTCTTGATGGAGATATTGCTGCGCTAGAGTAGTTTTGCCTAAGCCTCCCTCACCTTGGATGACAATGACTTTCGAGCCTTGATTTACCAAATTATTCAGGTGAGCGATCGCTTCTGTTCGTCCAATAAAATTGGTATCCTCTAATTTTGGGGTGGGATGTGGCGATCGCGAGTAATCAATCAGACTGGATGATATCGCAGTAGTTTTTCTCAGAACCCGTTCCAAAGTAGCGCGACAATTACTTTTGGTAATCTTTTCTCGCAATACTTTAGAAAGCAGCTTCCATAACTGAGAACCCGCATCCTTGGCGTGTCCTTCGGTACAACCGTAAGAATGAGCGATATCCAAATATTTTCTACCCAACCAAACTTGCACAAGAATCACTTTTTGCAAATCGCTCAACCGTTCCCCAGTCTGCGGGGGAATTGTGGCATCTAACCATGCTAATGCTGCTTCAGCGTCCATTGTGTAACGACGAGGGGAGTTCAGATTTTAGGGACAACTATAAATTACTCTACAGTTATATTGCGGGAGTTTTCGGATAAGATTCTGTAAACCCGACTTTTTTCCCGACTTTTGCAAACTTTATTCAAAATTCAGCCGCAATTTTCATTGCTTCTTGTGAGTGCAACTAATGGAGTCTCTTGCAAAAGCCACTTAATTGACCCAAAAAATTAATTTAGTATCGCTAGTTCTTTAATACGTTTGTCAATTAGCTCAATCTTGTAATAGTCAAAATTAAAGTTCCATGATTGTTAAAATACATTATTGGGAGATCATTGGCATAACAAAACAACTCCCCACTTGAAGTAGCTTTATATTTCTCCAATTTCTTCCCAATTAAGAACTCTTGTTCAGCAGACTGGCCAATATTCCCAATTAGGGAAAACCAGTTTTCGTTTGGTTTTCTGCGGAACATCTTAGCCCAACGTAGCCACGGTTTTGTATACCCATCTGCATCACTTCTAATCTTGGCATCATACCAAAACTGTTCTCCTTGTACTTCAAACTTATAACTTGCTCCTATTTCTAGAAAAATACCAGTGGCGTTCCAGTATTTCTGAGCGTCTATTATTGTTTCTGATGGAGAGCTAATTTGTAGCTTTGTCATTTTTGTATTAATTTTACATAATTGTAACGATGAACCGGAACATCACTTATTACATACGAATAATCACTTGCCAAAGAAAAAACATTAAGGAGATAAGTTTAGAAATTTGTATTACTTCAATGCCTTGAATAATCTTTTTTTAACCTCTTATTAATTTGAAAAGCTTACTCTTCTTAGATAATTGAGGCTAGCTATTTACAACAAATTAAGCCTCATCTAAAACATCAGGGAGTATACATTGAATTTATCGAGACGTGAGTTTTTTACCCTGGCAGGAGCATCTGCTACAGGTGCTGTCCTTCTATCTCCTTTGCAAGCATTTTATGCTAAACCTGCGATCGCTGCGGGCCCCTACGGCAATTTAGTGACCGACCCCAACGGAGTATTAGATTTGCCATCAGGATTCACTTACCGCAGACTATCCGAAACAGGCCAAACGATGAATGATGGTTACTTAGTACCGGGTGGTCACGATGGTATGGGTGCTTTTGCCGGGTCTAATGGCAATACGATTCTAATTCGCAATCATGAACTCGGTACTTCTGGCAATGGTGTGGGCGCTCCCAATGTCAGCAAGTACAACACAAATGGGAGGGGCGGTTGTACTAAATTGGTTGTTAATTCTTCCCGCAACCTGGTAGAACATCGGGGTGTCCTAGCTGGAACTATTCGCAACTGTGCTGGTGGCCCTACGCCTTCAGGGTCATGGTTAACCTGCGAGGAAACTTTTGAAAGCAATAACGGCAAGAAGCATGGTTATGTGTTTGAAGTTCCCAGTAGTGCAAATACTTTTGTCACCCCCGTCCCACTAACCGCTATGGGGCGTTTTAATCACGAGGCTGCTGCTGTAGACCCCAACACAGGGTATATCTACATGACAGAAGACCGGAGTGATGGGCTTTTCTACCGCTTCATTCCCAACCAAAGCAACAACCTGAGTGCTGGCGGCACGCTATACGCTTTAAGAATTACGGGGTCGTCTGGAATCAACACAGCTACGGGTTTCCCAAAAAATACGCCTAGGGCGGTGAACTGGGTACAGATTAGCAATCCTGATCCCACATCTGATACTGTCAGAACAGCAGGGTATAACAGCGGTGCCGCCAGGTTTTCAGGTGGGGAAGGCATCTTTTATGGCAGTGGTTATGTCTACTTCACTTGCAAGAGTGGTAGTAGTTCTGGAAATGGGCAGATTTGGCGTTATTCGCCCGCTAATAATACCGTTGAACTCTATATTGAACCCAACAATTCTGGTGTGCTAGACAATCCAGACAATATTGTGGTTTTCCCCAACCGGGACATCTTTCTCTGTGAAGATGGGGATGGAACGGATTACATTCTGGGCATCACTCCCAGTGGAAGTCTTTATAAGTTTGCTAAAAATGCCCTCAACACATCAGAGTTCGCCGGGGTCTGCTTCTCCCCCGATGGTCAGACGATGTTTGTCAATATGCAGAGTCCAGGAATAACCTTTGCTATCTGGGGGCCCTGGTAACGCTACATCCTGTTTCAGCCTAGCCAGAGCGATCCCCCTGACTAGGCTCTTATCCTGACTTCAATCAGACAGTCTGACTTGATATACTCCCCCGAATCCACTTCGCTAAATTCGGGGGATTCTAGGCTCAGACAGCGATATTTTCTATCGTACCTATGCTGAGAACCTCCGGCTTTTAGCCGGGGGATGAAAGCTATCCGCCTGATTTATCAGGCGTTTTAGTTTTAATTACTTTTTTGATTCTCAATATATTTTCTCACAACTTCTGTACTTGCTGCACCAGTCGAAGCGACAAAGTAACTAGGACTCCAGAGAGAAGGGAGTTTTTTCAGGTGCGGGAATTCGCGTCTGAGGTGATGAGATGCCCTCCCCTTAATCCATCTAGCTACATCAGCAGGTGACTCATGCGTTGGGACATTTAAAAAACAATGAACATGATCAGGCATTATTTCTAAAGCGATAAGTCTCCAACTATGCTCAACTACTAACTCTAATATAATTTCTTGTAAACGCTGTGCTACTTCTTTTATTAGCACGGCTTTTCGTCGTTTAGGAACAAATACAAAATGGTAGTTTAGGGATGAAACTGAGCCATTTGTCCGCCTGTATTCGTAGTCTGATGGTGATAATTTAGCCACTAATTAAATGTTGTTGACTTATACTCTAGCAACATTTATAGTAAGATATACAGGAGGTAAAAACAAGTGTACAAAACCTGTTCAATTAGGGCTAAATTTAATGACGAAGAAACAGCTTTTTGGTTAAACCAGTGCGAAAATGCTAATAGCTTGATAAATTGTGCATTGTACGAAACTAAGAAAATTCATTACGCCAAATTGCAAGAAAATGGTAATGCCTTTACTATTTATTGGCGTGGTGATGATTTACGTAGTGGATGGAAAACTTATAGATGCACTACAACTTACCCTGAGTTAGACTTAATTCTCAAACAGAATGTGCATTACAAAGCAATGGCGGCTCAATCAGCACAACAAACGCTAAAGTCATTTGGTGAGTCAATTACAGCCTATAACGGACTGGTCAAAGCTTATTACAACGGTGAGGTTGATAAACCATCCTTGCCGAAATATCGCAAAAAGGGAGGTCTAGCTGCTGTTACATTTCCGCGTCAGGCTCTAAATTTTAATGAGGGATATTTCAAGCCATCAATTAGTAAAGAAAGTAAAGCAGAATTACTAACTGAAATTAGATTATATCTTCCAGAATTTATAGATTCAGCTTGGGTCAAGGAAGTAACAGTACGCCCTAACTTTGGTCAATTATGGATTGATTGGGTGATTGATGATGGTAAAGAGCCAATAGAAAATAATCCCCAATTAGATTACACGCAAGCATGGAGTTTTGACCACGGCGGTTCTAATTGGTTAACAGGTGTCTCAACCCGTGGGAAAAGTTTGATTATTGATGGTCGCAAACTTAGATCACTGAATCAAGGATATTCACGTTTAGTTGCTAAATACAAACAAGGCAAGTCAGATTTTTATTGGGATTCCAACCTTGATAGAGTGCAACGTAAGCGTAACAACCAGATGCGAGATGCAATCAATAAGGCTGCTAGATTTATTGTCAATCAATGTCTTAACGATAAGGTGGGCAACATTGTTATTGGTTGGAATGTTGGACAGAAACAAAATTCCAACATGGGAAAAAGAAATAACCAGAATTTTGTAGTTATCCCAACCAGTCGATTAATTGAAAGGTTAAAACAACTCTGCCCGGAATACGGAATTATTTTAACAATTACCGAGGAAGCATATACAAGTAAAGCATCATTTCTTGATTGCGACTCCCTGCCCAAGCATGGCGAAAAGCCCCAAGGGTGGAAAGCAAGCGGAAACCGCATAAATAGAGGACAGTACAGAAGCAAAGACGGCTCCATTGTTAATGCAGATTGCAATGGAAGCGCAAACATCATGCGAAAAGTAGCCACACAGCTAGGGTTAAATCTAGCCGAGGTGGGTAGGGCATCTTTGACAGTGCCACAGCGAATTGATTTGTTTACGCGATTATCCAAATCATATCGCAAACGTTGCGGAGTGGGTCTTTTAGACCCCATAGCAACATCAGTTTAG

Protein sequences of DBSCAN-SWA_1

>NZ_CP046703|409936:492313|436781_437579_-|WP_114082680.1|DBSCAN-SWA
MAATSNQIKSKVWDNKQEYPLTIESLRMLWENRIPLIRLKEFATPQECEMLVNQAELFNFDCYQNVNPKIEKIGITVFEYNRISKAAYFQAVERTTKLRDCIMAASFNPLERLMVKIRECTGATVRIASEPLYGSYYAGLIRKIEQGTQLHIDYAPLEQSKWEIGTVIYQLSWNLYLKFSPNNHGQTRIYDRQWKSGDEQYKLDSYGYGDTVIADADAIAFQPYVGDVFIFNTRNFHTVEPMDGQRVTFTSAIGLLPNGEIILWS
>NZ_CP046703|409936:492313|437680_439285_-|WP_114082681.1|DBSCAN-SWA
MVLITKVDELFIRWNKPNSPGCAIAVIQNEEIIYQRGYGMANLEYNIPITSNSVFDIASNSKQFTAMCIVLLARQKLLNLDDELQKYIPEIPQYSHSITIRYLIDHTSGLRDYLHLMLFAGMRFENKYSNEEIIALIARQQSLNFEPGTEQLYCNSGYILLAEIVRRVSGKSLRVFAQEHIFAPLGMKNTHFHDNFREIVKNRADGYAPKDGEGFQIDMSFHDFCGDGQLYTTIEDLLLWDRNFYHNILGGYGQDLIEEITTPRQLNNGEIISGAFGLQIGDRGGLKTISHGGSWTGYRSDFIRFPERQFSVICLANLSTLKPTKLAFQVADIYLENDYIENITKPISRSISSINLPVVELQLKAGFYHNPTTGSILELEIKNGKLMAKLAWMYFQLIPIDTNHFQSVDNEIDYDIEFSEDIIHLIGKLDIGDGIKTYTFEKILDSPKDILADYPGTYYSAELERDFKINLVGNKLYYKSKGYAPSHLIVAGQNVFLRYLIYVDKFELVRDREGRVIGLYRCCDRVRRLYFSKQ
>NZ_CP046703|409936:492313|476311_476809_-|WP_114082693.1|DBSCAN-SWA
MNQSNPPLPSGCVLRKATLADKWSIRLLVFSAKLDPTQLNWQQFWVIEFGDNLVACGQLRNFSGAQELGSLVVASAWRGRGLGTLLTQHLINTATQPLYLECLGERLAQFYSRFNFAPISFEDLPQFPRTTGLSTLNDKFRLSQLAKKLLKVPVVFMEYRGHTNS
>NZ_CP046703|409936:492313|432371_432743_+|WP_114082674.1|transposase|DBSCAN-SWA
MAGRFEGLSDLEWKLFEDIFSEEASKRGKGMPHAPYRHVLNSLLYILITGCRWCDLPRGDMWASKSSSHRWLKRWRSDGTFAYLQARILAMPAAGYAYADEKGLINWDFGAVDGSFSPLVGRR
>NZ_CP046703|409936:492313|474044_474719_-|WP_114082690.1|DBSCAN-SWA
MTHILLVEDEVKLARFVELELNYEGYQVSIAYDGLTALTAARELHLDLVIVDWVLPGLSGLEICHHLRNISDKLPIILLTVKDEVSDRIVGLDAGADDYLVKPFSVDELLARVGTHLRRNWQVDSADVLEFEDLSLNRRTRQVYRDQRLIELTAKEFDLLEYLLAHPRQLITCDRILQEVWAYDFMSDANIIELHIRYLRLKLEANNEKCLIQTVSGVGYTLHD
>NZ_CP046703|409936:492313|478015_478345_+|WP_114082695.1|DBSCAN-SWA
MSLKIVQNFDGSFTLEAQAQETLFNLLTSDAFLNQIRQQLQCEQIKFTELIFQPVPYSLTTTKGMPAEFEKYHESDEYAIINVPPNFMFSAKIFKPSRLCAIYQKLGNG
>NZ_CP046703|409936:492313|478417_478966_+|WP_114082696.1|DBSCAN-SWA
MALETNLSSLAALEYIPYIDDSGQLPEQFQGKIGVYAIFDQEKVLQFVGYSRDVYLSLKQHLVRQPQQCYWVKVQTIERPSRTILENTENAWIAENGSVPWGNGDNKEKWTHPIDVKLIMTPEEQAKYQNPANDELAQMKIIKNVARRVEAEISTQLLEVRGLQMQVRFNPKLKEEGLLDLK
>NZ_CP046703|409936:492313|481180_481540_+|WP_114082698.1|DBSCAN-SWA
MLNIKNQRIFLPAFIQPLGQNNQADSKKELAKSKLDLLQPLRQWLDEIEIQNRKLAKFIAKLIPAQCPFERDIKLFGRKIGHIPPMCKLNPLYNELVYLRFRALCYLVDQCGEDIQSYC
>NZ_CP046703|409936:492313|471726_472686_-|WP_114082688.1|DBSCAN-SWA
MLLISLFIATLFLAYSNGANDNFKGVATLFGSRTSSYQTAILWATFTTLGGAATATFLASTLIKNFSGKGLVPDAIANSPEFHLAVAIATGLTVLIATLMGFPISTTHSLIGALVGAGLVAIGLKVNFAVLGTSFVLPLFLSPIIAIPFGAAIYSLSGYINSKWNLPVNQKMIDTCHFLSAGVVSFARGLNDTPKISSLILVIEYFSVQGGMITIAIAMALGGLLNSQKVAVTMSEKITSLNPPQGLSANIVTGILVIAASLFGLPVSTTHVSVGSIFGVGLIGKKANMRVFYQILLSWILTLPIAAIISGIIYRLLQG
>NZ_CP046703|409936:492313|453290_467702_+|WP_114082684.1|DBSCAN-SWA
MKLELSKTNRQNIEDIYPLSPMQEGMLFESLYAPDSGVYFEQITCILTGNLDVKTFEKAWQQVVARHPVFRTAFLWESLSQPVQVVYRQVNVTVETYDWRELSTQEQQQQLESFLDSERQQGFQVSQAPLMRLHLIQLDGDTYQFVWCHHHLLLDGWSSPLVFQDLLEFYQAISQGKSLSNTGTVSYRNYIAWLQQQDRDLAKEFWRQKLQGFTTPTPLTVDKPLSMREKHSGYSEQQIDLTVPATAAVMSFVRQHQLTMSNLVQATWGLLLSRYSQETDVVFGATVSGRPPELVGVESIVGLFINTLPVRVQISEKTELLGLLKDLQAQQIESEQFSHSSLAEIQGLSDVPKGTPLFESIVVFENYPIDTSALQGDRNFSLSNFRWIEQTTYPLAVVVSPGEQLSLRVMYDASRFEDGTISRMLGHFVTMLEAMSDDKPLCVYATNPQQRISQLPMLTESEQQQLLVDWNDTQSNYPQDKSIHQLFEEQVELTPDAVAVVYENQHLTYRELNSRANQLAHYLKSLGVKADALVGICVERSLEMVVGLLGILKAGGAYVPLNPEYPQERLTFMLEDTQLSVILTQEKLVNKLGERLRRGFAERNASVICLDSNWDIINQQTQNNPTTSVTADNLAYVMYTSGSTGQPKGVSIVHRSVVRLVKETNYISISADDVIAQASNHAFDAATFEIWGALLNGARLVGVSKDLALSPRDFAVFMRSQSISVLFLTTALFNQIAQEVPSAFNSLRHLLFGGEAVDPKWVKEVLNNGAPQRLLHVYGPTENTTFSSWYLVQDVPEGATTIPIGQPISNTQIYLLDSQLQPVGIGVPGELYIGGDGLAREYLNRTELTQEKLIQNPFGGSRGAGEQGSKGAEEQSFPSASSERLYKTGDKARYLSDGNIEYLGRIDDQVKIRGLRIELGEIEAVLSQHSDVQVSCVIVREDTPGDKRLVAYIVTHQDCQPTMGEIRQFLKAKLPDYMIPSAIVILESFPLTPNGKIDRRALPKPDLDTALLEKYVAPRTPVEEMLALLWAQVLKVEQVGIYDNFFELGGHSLLATQLVSRIRTSFKIELPLRELFAASTITELAPFIQQLQQQDLQLAAPPILRRAENANLPLSYAQQRLWFLDQFEPNSASYNIPFGLRLVGTLNVAALQQSLIEIIHRHEALRTNFITVDGQAAQIIHNWREQGTGNREQENIPWTLSVVELKHLPVTEQKTAAQKLVQQQALLPFDLESEALIRATLLVLSHTEQWLVLCMHHVVSDGWSIGVFIEELQALYNAYSQGQPSPLLPLPIQYADFAIWQRQWLQGQVLNSQLSYWKQQLANAPTFLPLPTDRPRPAVQTFNGAYQEFTLSGELTQRLVQLSQKQGVTLFMTLLAAYNTLLYRYTGQEDILVGSPIANRDRTEIEGLIGFFVNTLVMRTEISGDRSFNELLPRIREMALSAYAHQDLPFEMLVEALQPERDLSHTPLFQVMFVLNNAPTSEVELTGLSVSELSIESAIAKFDLTLGMQNTNNGLVGWWEYNTDLFDSSTIKRMTGHFVTLLEAIVANPQERISQLPMLTASEQQQLLVEWNDTQVDYPQDKCIHHLFEEQVERTPDAVAVVFKNQQLTYHELNCRANQLAHYLRSLGVSADVLVGICVERSLEMVVGLLGILKAGGAYLPLDPEYPQDRLSFMLEDAQVSVLLSQHHLVEKLPEHHARVVCLDTDWQIIPQSNQQNPIAGVQASNLAYVIYTSGSTGKPKGAINTHLGICNRLLWMQQAYQLTEIDCVLQKTPFSFDVSVWEFFWPLLTGARLVVAKPDGHKDSGYLVNLILEQQVTTLHFVPSMLQIFLEEQGLKDCSSLKRVICSGEALPKELQERFFACLGCQLHNLYGPTEAAIDVTFWECQPESNLKTVPIGRPISNTQIYILDQNLQPVPVGVPGELHIGGAGLAKGYLNRPELTQEKFIPNPFSGSRRAGEQRSRGAGERRRKIVQSPVASPRLYKTGDLARYLPDGNIEYLGRIDNQVKIRGFRIELGEIEAALSQHKDVQTSVVIVREDIPGDKRLVSYIVLQPEQTTTVKELRSFLKEKLPDYMVPSAIAILESLPLTSNGKIDRRALPAPEPSGTLSDKYVAPRTPLEEILALIWQEVLKIELVGRYDNFFTLGGHSLLATQLVSRIRSSLKVELPLRSLFAAPTIAELAQLIQQLQQQDLELAAPPILRRTNNAELPLSYAQQRLWFLDQFEPDSPFYNIPIGLRFVGSVNIAALEQSFKEIIHRHEALRTNFVSVDGKPTQIIHQIEPNWSLTVVELQHLALTEQEIAAQKLVQQQAIEPFDLAHDALIRATLVVLSPIEQWLSVSIHHVVSDGWSIGVFVEELQALYNAYSQGQPSPLLPLPIQYADFAIWQRQWLVGEVLNNQLSYWKEQLANAPTFLPLPTDRPRPAVQTFNGAYLEFALSVELTQQLTKLSQQQGVTLFMTLLAAYNTLLYRYTGQEDILVGSPIANRDRTEIEGLIGFFVNTLVMRTEISGDRSFSELLTRVRDMAMEAYAHQNLPFEMLVEALQAERNLSHTPLFQVMFVLQNAPTASGLDLTGLNVSPLPVKLTTSRFDLTLIMQNSPTGLIGLWEYSTDLFDASTIDRMTSHFVTLLEGIVANPQQQISQLPLLSEVEQQKLLFEWNDTQVDYPLDQCIHQLFEEQVKLTPNAVAVEFKEQQLTYNQLNDRANQLAHYLQSLGVKPDTLVGLCVERSLEMVIGLLGILKAGGAYVPLDPEYPTERLSFILEDTQVKVLLTQRSLLDRLPQCEKAGGQGAGSRGESPSTRDRASTKGKEEVLSLPASYQTQLVCLDTDAELISQCSQDNLITGVQANNLGYIIYTSGSTGQPKGIAMNQLALCNLILWHPDNLKIARGAKTLQFASINFDVSFQEIFTTWCSGGTLFLITKELRHDTSNLLRVIQEKAIQRMFLPVVGLQQLAEFAVGSELVNTHLREIITAGEQLQITPAISKWLSQLSDCTLHNHYGPSESHVATSFTLPNLVNTWPLLPPIGRPISNTQIYILDKYLQPVPIGVPGEVYIAGVLLARGYLNRPELTQEKFIQNPFGGSRGAGEQGSRGAEEQSFPSAPHSLCPSASSERLYKTGDLARYLPDGNIEYLGRIDNQVKIRGFRIELGEIEAVLSQHINVQASCAVVREDTPGDKRLVAYIVPQPEQRVSVNVVRSFLKEKLPEYMLPSAIVILEALPITSNGKLDRRVLPAPDLHSQLSDQYVAPRNPIEEILSLIWAQVLKVELVGIHDNFFELGGHSLLATQLVSRIRTNLKVELPLRELFAAPTIAQLAPIIQRLQQQDLELIAPPILKRAENAELPLSYAQQRLWFLDKLNPNSASYNIPIGLRLVGTVNVAALEQSLIKIIHRHEALRTNFITVDGKLSQIVQTQTNWTVAVVDLQHLPVTEQEIAAQQLVQQQAIQPFDLANEALIRATLMILSETEQWLLVCMHHVVSDGWSIGVFVQELQALYNAYSEGQPSPLTPLPIQYADFALWQRQWLQGEVLKSQLSYWEQQLANAPTFLPLPTDRPRPAVQTFNGAYLEFALSGELTQRLVQLSQKQGVTLFMTLLAAYNTLLYRYTGQSDILVGTPIANRDRTEIEGLIGFFVNTLVMRTDLSLNPSFNELLPRIREMALSAYAHQDLPFEMLVETLQPERDMSHTPLFQVMFGLQNAPMSEIELTGLTVSSLPIESSTAKIDLTLSMENTSTGLVGGWEYNTDLFDSSTIERMTGHFLTLLEGIVANPSDRISQLPMLTASEQQQLLVEWNDTQVDYAFDKCIHQLFEEQVERTPDAVAVVFENQQLTYHQLNCRANQLAHYLRSLGVKPDALVGICVERSLDIVVGLLGIFKAGGAYVALDPDYPQERLRFMLEDAQVSVLLTQQRLIHRLPEHQAKLVCLDEAWEEIAQNNQDNLSSGVKASHLAYVIYTSGSTGRPKGVMVEHRGLCNLTHAHIQTFGLDSDSRVLQFASFSFDASIWEVVLALGSGATLYLGTKDSLLPGKPLIEQLRNNCITNITLPPSALAVMPMEELPALQTIIVGGEACSAELIRQWSAGRNFFNGYGPTEATVCATIAKCTEDDEKISIGKAVANTQVYILDENLQLVPVGVPGELHIGGAGLARGYLNRPELTQEKFIPNPFAGSRGAGEQGSKGAEILPNSQSPVPSPRLYKTGDLARYLPDGNIEYLGRIDNQIKIRGFRIEVGEIEAILSQHPGVRENVVVAREDIPGEKRLVVYFVPQLEQTPTTDDLRIFLKEKLPQYMVPSAFVRLEFLPLTPNGKVDRKALPIPDSHNTQLAVSFVAPRTPVEKVLADIWANVLHLEQVGVLDNFFELGGHSLSTIRVMSQVNETFQINLPLRHLFAAPTIAELAQTIESTCETDSTVSTNEITPLNLQAEVVLDETIKPFNLVYQPVSEPKAILLTGATGFIGAFLLAELLQQTQADIYCLVRAANLSAGKQRLQETLKAYLLWEESFNSRIIPVLGDLFQPLLGLGDEQFHFMARKIDLIYHNGALVNHVYPYALLKAANVGGTEEVLRLASQIKIKPVHFISTVSVFASDEYFKLDVVQENDPLEHSQGLLGGYTQSKWVAEKIVMMARDRGLPCSIYRLGRITWHSQTGAWNSNDMFYRFIKSCIQLKSAPEMNSTVEITPVDYLTKALIHLSQQPESLGKAFHLINSDSAPWSQFINCIRSLGYPLQQLPYEDWQAELLRNTQISADNALYSAISLAEDNTSSESNATSSLKFDCQNTLNGLADTTIRWPEVDDKLLQAFFANFSNSTLDKKK
>NZ_CP046703|409936:492313|409936_411158_+|WP_159402611.1|transposase|DBSCAN-SWA
MQLTDSLKKLLKETAHQLKGAAKRRFIAQTVVALRHGGKSIAERELGWNRVTIGKGIKELNSGITCVDNYQGRGRKKAEEHLPTLLEDIKKLVDSQSQIDPTFKSQRLYTRLGASVVRHQLIEKFGYAEEELPTSETIRVKLNDLGYRLKRVAKIQPQKKFPETDAIFEQLAIVHQEASDDPTILRLSLDAKARVNIGSFDRGGRNRVPTETDDHDFKPKTTVAPYGIFLPDLDELFLYFTESKVTSDFIVDILGDFWKSESWRFSEIKTLLINQDNGGENSSRRTQFMKRIVEFAQSYKLNIRLAYYPPYHSKYNPIERTWAVLENHWNGSILDDVETALNFAKTMTWNGKSPVVKLVTQTYSSGVRLTKKAMQEIENKIERLTNFTEDNLPNLGKWFIDICCGVT
>NZ_CP046703|409936:492313|474913_475201_-|WP_114082691.1|DBSCAN-SWA
MTSFIQVRSHNDLLHPVREWLEKIEIHNSKLAHFLCKAIPAQCPFEQDITLFGRKLFHIPPMCKLNPLYEEVVGLRFKALCYLADKCGEDVTSYC
>NZ_CP046703|409936:492313|435626_436733_-|WP_114082679.1|DBSCAN-SWA
MPLAAVMTAPNQPVEVQQLPDPVLEKGGIILETLYSEVCGTDVHLLHGRLEGVPYPIIPGHFSVGRVVETGGAVSDVNGKLIQPGAIATFLDVHETCYNCWYCLVAKASTRCPKRKVYGVTYSAKDGLLGGWSELIYLKPGVKVLTLPEEVSPKQFIAGGCALPTALHAIDRAQIQIGDVVVVQGCGPVGLSVAILALLSGAGKVIVIDKFESRLVVAKSFGVDETLAIKADDPRQHIERVLELTNGHGADVTIEATGIPIAVKEGLNMTRNGGRYVIVGHYTNTGEILINPHLEINLKHIDIRGTWGIDFSHFYRMIELLKRHSDSSKNIAWSSIISRSYTLQQINQALADVEQGSVLKAVIQPNLS
>NZ_CP046703|409936:492313|413461_413611_-|WP_159402431.1|DBSCAN-SWA
MVITHLSNINPPLPQGAIVGCGGAVVTRIGEKRSLTLGALSQKYSTEHP
>NZ_CP046703|409936:492313|490444_490858_-|WP_114082705.1|transposase|DBSCAN-SWA
MAKLSPSDYEYRRTNGSVSSLNYHFVFVPKRRKAVLIKEVAQRLQEIILELVVEHSWRLIALEIMPDHVHCFLNVPTHESPADVARWIKGRASHHLRREFPHLKKLPSLWSPSYFVASTGAASTEVVRKYIENQKSN
>NZ_CP046703|409936:492313|488963_490220_+|WP_114082704.1|DBSCAN-SWA
MNLSRREFFTLAGASATGAVLLSPLQAFYAKPAIAAGPYGNLVTDPNGVLDLPSGFTYRRLSETGQTMNDGYLVPGGHDGMGAFAGSNGNTILIRNHELGTSGNGVGAPNVSKYNTNGRGGCTKLVVNSSRNLVEHRGVLAGTIRNCAGGPTPSGSWLTCEETFESNNGKKHGYVFEVPSSANTFVTPVPLTAMGRFNHEAAAVDPNTGYIYMTEDRSDGLFYRFIPNQSNNLSAGGTLYALRITGSSGINTATGFPKNTPRAVNWVQISNPDPTSDTVRTAGYNSGAARFSGGEGIFYGSGYVYFTCKSGSSSGNGQIWRYSPANNTVELYIEPNNSGVLDNPDNIVVFPNRDIFLCEDGDGTDYILGITPSGSLYKFAKNALNTSEFAGVCFSPDGQTMFVNMQSPGITFAIWGPW
>NZ_CP046703|409936:492313|411331_413098_-|WP_114082663.1|DBSCAN-SWA
MSKFLTWIELLSYRAIHQPDKIAYIFLQEGEKETLRLSYQQLDILSRAIASQLQSLELTGERALLLYPPGLEFIAAFFGCLYAGVIAVPAYPPRPNQKMTRLSAIVSDASAKIVLTTNSLLKNIKRSFDQNSELNTLHILATDNIDSNQAKNWQKSEINSENLAFLQYTSGSTGTPKGVMVSHDNLLHNCEYMKQAFAFTPASVAVSWLPSFHDMGLILGILEPLYTGVPVILMSPTAFVQQPIRWLQAISHYNATHSGGPNFAYELCINRITQEQLATLDLSTWRFAYNGAEPVRRHTLERFAKKFQPCGFRSNFLYPCYGMAEATLMISGGLGEAEPVYCTVKADELAQNQIVEASSNTQNVRQLVGCGCEWLDTKIVIADPESLTQCLLNQVGEIWISGRSVTQGYWQRPEQTEETFKAQLRGTKEQPFLRTGDLGFLKDGELFITGRLKDVIIIRGRNHYPQDIELTVQQSHPALRPDWGAAFAVEVEGEERLVVVQEVHRNYLRELNVDELVGAICEAVSEQHELQVYAVLLLKTASILKTSSGKIQRHACKNGFLTGNLNVVGEWRQNFNENRPHLLGTSRE
>NZ_CP046703|409936:492313|479013_480498_+|WP_114082697.1|DBSCAN-SWA
MTIQLLNDRYQVIRTLGAGGFGETYLAEDTYMPSKRHCVVKQLRPIHNNPQIYQLVQERFQREAAILEELGGANDQIPALYAYFSSGGQFYLVQEWVEGDTLTGRVQKQGLFSEGAVQELFMNLLPVLDYVHSKHIVHRDIKPDNIIVRHRDGKPVLIDFGAIRESMGTVVNSQGNPTSSIVIGTPGYMPSEQAAGRPVYSSDLYSLGMTIIYLLTGKQAQQLETDSQTGEIVWRQYASHVSPIIAGAIDKAIAYHPRDRYPTARAMLDTLQNIANPIPPTQPILTQPTIVSAPPPQTLPVKPQPNPQGNSQNNILMGSLIAGGLIGASVIISQVLTKPTQSTADKTVLPSETPSTITSPVIETPKFIPTTPSVPTQPSSVPTQITPAPTTSIPPVSTTTANTYLWLSQRLVNDADLDGKDGFELDIMRNSIFASHGRRFDTPGLQDYFDNQPWYKPIYSPKAFPSKLLSKLEQQNIEYINKYQERYGLRYFKK
>NZ_CP046703|409936:492313|439383_441402_-|WP_114082682.1|DBSCAN-SWA
MPTQVVQAQPSTNAFLGFIQFWKDVKAVAQPYWYPNEPGDRAFSEVIRSWGMLILLILLIIVLVGANVFNSFINRYLADIIIQEKEISKFYDALLLYGSALALGTLLAGFSRLVRKKIALDWYQWLNNQILSKYLNSRAYYKINFTSSIDNPDQRLSQEIEPIASNALSFSATLLEKILEMTAFLLVLWSISQSVALILVSYTVIGNFIAVYLTQELNKINRQELEAKAEYTYCLTHFRTHAESVAFFRGENQELNIINRRFSNLIKNAKRKIDWEKNNEIFNRGYQSVIQIFPYIVFGPLQIRGEMEFGEIIQASVCCYFFANALGELINEFGNSGRFSSYVERLSEFSDALEAVTKEPEHITTIKTIEENQIAFENVTLQTPDYEQVIVEDLSLSVKAGEGLLIVGPSGRGKSSLLRAIAGLWNAGTGRLVRPPLEEVLFLPQRPYIILGTLREQLLYPTTNSQMTDAELTKVLQQVNLQNLLSRVDSFDTEVPWENILSLGEQQRLAFARLLVTHPRFTILDEATSALDLKNEGGLYQQLQDTKTTFISVGHRESLFDYHQWVLELTEDSSWQLMRVQDYREQKGQKVSITKSTANVQIKIDDSSQDKSLNDSESSTTKKLSHKEMNELTYYSVSTIRSKASKGEFITTRDGITYGYDKDPKILKWVRV
>NZ_CP046703|409936:492313|419083_420214_-|WP_114082668.1|DBSCAN-SWA
MVKFNSKIFLFFTISGTLIVLTSNSTLASLLYQEKPTVTNQVLISVEFKFPNDAAPKTSVGGGVRGQVQFTLPGGSAPRTSVGGGTRGDVQFALPGGSTPKTSVGGGTRGDVQFALPGGSTPKTSVGGGTRGDVQFALPGGSTPKTSVGGGTRGDVQFALPGGSTPKTSVGGGTRGDVQLTLPSGNSTPRSSIGGGTRGKTAPLTALVPPTKQGRTVLASPTIFVYLPPVGAETVFFSLQDEDGNPHYSTMLKVPPDGGVVSITLPPAAPPLVIDKNYLWYFAPIEPGGILRPDNYSVTGWIKRVKATFNEQELASSPVELATKYAEAGVWYDTLKILAAAKRSQPNNKAFATEWHDLLKQVGLENIASQPLTDAF
>NZ_CP046703|409936:492313|415987_416608_-|WP_114082666.1|DBSCAN-SWA
MLPISTVSTIIKTESFGDLISDFPPEHDSLELYFTPSSRPIKQRWRSNRLSAHFFADYFANFLAVDEDEPNQEQIIKENKSAVSYVANELLENAIKFNDDSSNYKVRIGIHFLNNADSVTAVIFASNSIKLETEAKLRAVIEKILTSNTHEMFVHQVEKSAEKNGTSGLGLLTMINDYSAKIGWKLETIQQESIIMAVTTMAQFKV
>NZ_CP046703|409936:492313|415582_415936_-|WP_114082665.1|DBSCAN-SWA
MVLQEIKDGDYTVEADTDSATVNFKGELSLGGSSEYEPITNLLNKIAATDPATMTLNLRDLAFLNSSGISMLSKFVLSLRKKKGIQLLVLGSNTMPWQGKSLKNLERLLPGLKLEIE
>NZ_CP046703|409936:492313|442086_453294_+|WP_114082683.1|DBSCAN-SWA
MNLIKLLENLSAKNVELWVDGDKLRYRSPENSLTPELLREIQQSELEIIQILSQSTAQAATYPLSHGQKALWFLYQLARNSTAYNVTYAAKLVISLDILALKQAAQALVERHPLLRTTFATIDDEPVQTVHENQQVDFSIQEASDLGQDDINNWLSEKSDRPFDLEQGPILRFDLLINHIKTDKLATKEHILLITLHQIVGDFRSLEIIIGELRALYKAMSTTGYAYATGETAQLSTQNYQYQDYVKCSEQMLASSHGESLWAYWQQQLSGELPLLNLPTDRPRPQTKTYNGASRFFTVEKELRQKLTELATRESASLYILLLTALQILLRRYTNQEDILIGSPMVNRSRSEFESIVGHFTNPVVLRGDLSGNPTFEEMLERSHSCVLDAQDHQDYPFSLLVEQLQPVRNPSFSPLYQVAFVCDRSHQNIDINDDLILESMIPESKGAAFDLTLTIFEGTDSLKGTWNYNTDLFDDSAIARMMGHFVTLLEAIVANPQQRIDQLPMLTQSEERQLLVEWNDTQVDYAFDKCIHQLFEEQVKRTPDAVAVVFENQQLTYRELNSRANQLAYCLQSLGVKPDVLVGICVERSLEMVVGLLGILKAGGAYVPLDPEYPKDRLNFMLADAQVPVLISQQRLLDRLPEYQAKLICLDEVWSEILQNKQNNPIEVVKSTDLANVIYTSGSTGKPKGVMVEHSGLCNLAQAQIQVFGLSGDSRVLQFASFSFDACISEILMALGSGARLYLGTKDSIMPGMPLIERLKNDGITHVTLPPSALAVLPVEELPTLQAIVVAGEACPLELMRQWSKGRNFFNAYGPTEASVCAAIAKCTPEDEKITIGRPIANAEIYILDSQLQPVPIGVPGELHIGGAGVARGYLNRNELTQQKFIPNPFSRSRGAGEQGSRGRERLYKTGDLARYLPDGNIEYLGRIDNQVKIRGFRIELGEIEATLSQHPHVQASCVIAREDIPGDKRLIAYIVLQPEQTATVKELRSFLKEKLPEYMVPSAIAILESLPLTPNGKIDRRALPEPTSELSEKYVAPRTPIEEILAVIWQQVLKLELVGRHDNFFELGGHSLLATQFISRVRSRLKVEISLRELFAAPTIAELAPSIQQLQQQNIELSAPPILRRVENIEIPLSYAQQRLWFLNQLESNSALYNIALGLRLVGTFNFAALEQSLKELIDRHEVLRTNFVTVDGKPTQIIQTQTNWTVAVVDLQHLPLTEQQTAAQKLLEQKAIEPFDLAHDALIRATLVMLSPKEQCLLVSMHHVVCDGWSIGVFVQELQALYNAYSIGQASPLLPLPIQYADFAIWQRQWLQGEVLQNHLSYWEKQLANAPTFLPLPTDRPRPAVQTFNGSYHVFTLSVELTQRLLELSQQQGCTLFMTLLAVYNTLLYRYTGQSDILVGTPIANRDRTELERLIGFFVNTLVMRTDLAGNPSFNELLLRLREMALSAYAHQDLPFEMLVEALEPERDLSYTPLFQVMFVLLNAPMSEIELTELSVSGLPIEITTSKFDLTLSMENTPNGLFGWWEYNTDLFDSSTIERMTGHFLTLLEAIVANPSERISQLPMLTASEQQQLLVEWNDTQVDYPHDKCIHQLFEEQVERTPNAVAVVFENQQLTYHELNCRANQLAHYLRSLGVGADILVGICVERSLEMLVGLLGILKAGGAYVPLDPEYPQERLSFILEDAQVSVLLTQQHLVDKLPECQAQLVSLDTNWQFISQLPQGNPITNVQASNLTYVIYTSGSTGQPKGVQISHTAVSNFLSAMQQRPGITEQDTLLAVTTISFDIAALEIFLPITVGACLVIARRDVTLDGRELCDLLVKSKATIMQATPATWRLLLDSNYQFSDLKILCGGEALPWDLVSKLLARSASLWNLYGPTEATIWSSICQLESSESLISIGRPISNTQIYILDQNLQPVPIGVPGELHIGGAGLARGYLKRPELTQEKFIPNPFEEAGGRGQEAGGSRLYKTGDLARYLPDGNIEYLGRIDNQVKIRGFRIELGEIEAALSQHPHVQASCVIAREDTPGDKRLVAYIVPQPQVTLTISELRSNLKEKLPDYMVPSAIVILESLPLTPNGKIDRRALPAPEPSSELLEKYVAPRNPIEEILSLIWQQVLKVDLVGRHDNFFELGGHSLLATQLISRVRSSLKVELPLRSLFAAPTIAELSNNIQQLQQQDLELAAAPILRRAENAETPLSYAQQRLWFLDQFEPNSASYNIPFGLRLVGTLNVVALEQSLIEIIHRHEALRTNFITVDGQATQIIHNWKEQGTGNREQENIPWTLSVVDLKHLPLTEQKTAAQKLVQEQAFLPFDLAHDALIRATLIVLSPTEQWLLVCMHHVVSDGWSIGVFSQELQALYNAYSQGQPSPLLPLPIQYADFAIWQRQWLQGEVLQSQLSYWKQQLANAPTFLPLPTDRPRPAIQTFNGAYQEFALSSELTQRLVQLSQKQGVTLFMTLLAAYNTLLYRYTGQTDILVGTPIANRDRTEIEGLIGFFVNTLVMRTDLSLNPSFNELLPRIREMALSAYAHQDLPFEMLVEALQPERDLSYTPLFQVMFVLNNAPTSEVELTGLSISSLPIESAIAKFDLTLSMENTSTGLVGGWEYNIDLFDSNTIERITGHFVTLLEAIVANPQERISQLPMLTAFEQQQLLVEWNDTSVDYPQDKCIHQLFEEQVERIPDAVAVVFENQQLTYHQLNCRANHLAHYLQSLGVSADVLVGICVERSLEMVVGLLGILKAGGAYVPLDPEYPQERLTFMLADAQVSVLLTQQHLVEKLPRHQARVVHLDKDWVAIAKSSQENPIAQVQASNVAYVIYTSGSTGQPKGVILSHSNLCNHMFWMQATFPLTKEDKVLQKTPFGFDASVWEFYAPLLAGGQLLIAEPRGHTDSAYLLRLIAQQQVTTIQLVPSLLQMLLEQGGIETCHSLKHVFCGGEVLPVTLQESLLSKLDVNLHNLYGPTEACIDATFWNCQREIYPQLIPIGRPIDNTQIYILDQNLQPVPVGVPGELHIGGAGLAKGYLNLPELTQEKFIPNPFQGSRGAGEQGSRGRERLYKTGDLARYLPDGNIEYLGRIDNQVKIRGFRIELGEIEAALSQHSDVQTSVVIVREDIPGNKRLVAYVVPQPQITPTVSQLRSFLKEKLPEYMVPSAIVTLESLPLTPNGKIDRRALPEPEARTGIESSLVAPRTPIEEKLTRIWEQVLRVEQIGIHDNFFELGGDSILSIQIISRAKVAGIELTIKQLFANQTIAQLATVAGTTKALAIEQGLVTGTLPLTPIQHWFFEQKLPEKHHFNQSFLLTVPSDLNLEILEQVWQQLLKHHDALRLRFTRTDTIWQQIHAAPTDNITIPRFDLSTVPETEIETVIETTANELQASLNLSENLVQVAFFWLGIDKKARLIIVIHHLVVDGVSWRILLEDLQTAYQQLSQGKTIQLPAKTTSFKDWARQLTEYAQSEVLKSELDYWLSPSYDTVDSIPVDYAQGINTTASARTISVSLDEAETLSLLQDVPKAYKTQINDILLTALVLVLSEWTNSDSVLFNLEGHGREEIIDGVDLSRTVGWFTTIFPVVVELGTIDDLGTALKSVKEQLRVIPNKGIGYGLLRYLNIDAEISTQLEKIPQAEISFNYLGQFAQVVNTSSLMQIANEPSGNSQSLQGQRHYLLDINAIIINEKLQIDWTYSSNIHQYETIENIAQEFVETLQELIAHCLSTENAGYTPTDFPLIQLNQLEIDQILQNL
>NZ_CP046703|409936:492313|490924_492313_+|WP_114082706.1|transposase|DBSCAN-SWA
MYKTCSIRAKFNDEETAFWLNQCENANSLINCALYETKKIHYAKLQENGNAFTIYWRGDDLRSGWKTYRCTTTYPELDLILKQNVHYKAMAAQSAQQTLKSFGESITAYNGLVKAYYNGEVDKPSLPKYRKKGGLAAVTFPRQALNFNEGYFKPSISKESKAELLTEIRLYLPEFIDSAWVKEVTVRPNFGQLWIDWVIDDGKEPIENNPQLDYTQAWSFDHGGSNWLTGVSTRGKSLIIDGRKLRSLNQGYSRLVAKYKQGKSDFYWDSNLDRVQRKRNNQMRDAINKAARFIVNQCLNDKVGNIVIGWNVGQKQNSNMGKRNNQNFVVIPTSRLIERLKQLCPEYGIILTITEEAYTSKASFLDCDSLPKHGEKPQGWKASGNRINRGQYRSKDGSIVNADCNGSANIMRKVATQLGLNLAEVGRASLTVPQRIDLFTRLSKSYRKRCGVGLLDPIATSV
>NZ_CP046703|409936:492313|426919_429352_+|WP_114082671.1|DBSCAN-SWA
MKLNFTKHIEDIQLLHVERYLPEKIRTYIEENYYAKVQQQAELDYAVRDENFLANPLQHVALYSDHGVVHVRDVACNILVVLEAIHGVLIPKRESLWFDFMKGYGIILVYNHDMGMLDFSPFGRAMHPEFVTQEVFSSAFDQVIDTIWTENCGNVSWRLINLADKGALTEDPQLVLREMVSLGVAHSKSKVPIEVLNNPQQFRELMREIASVNLYHLYYQQQITKAENQLSHAKKSFQQQLKIEKLEVALQQIKATQTEFLKQGISPHNERIHRYYTDFEKQAFSWLVCEHPEVQALIADVGDTIRALRAADALRQRGTVYKTSGGYQIFVDQNTAKAIYALQKGSGELFLLEAANPLNAGEANIASSELTANGDIRISFNRGSFTNQDATQRAAYYLAIVIDDIQRDIIDTFHRSPDDNDVIKKSENIEILLENTDDNLDFAEAVQAELKKIAPEIGLKSRVVPSLKNIDPEERDRYLSAKELDWSLEQKQKILLRVSQSGHKIHNIDPHKAFTDVYLSSLEAGETLIQAGSPPGFVYIPMGIGLVSNPLGGYQPQCVKPWIPLGNIRVIRGDQQEATITAEEKLELLIIPKETYLKYWHNTYNAEEFSQQIVRIYAEDNLRELEQIFNILRQVALIDKNLDDTEVDFIQQMLDSYRIKYSTEELREKLLTGEDSDFVSLRQSVLDYLSLEPPYFQVGRLRDLLNLLVKIDENISAEESLIMSELNNLLDSYLADETLPKQYKILIIPTNSEQNEGIRAIFPTAPKVENPWGKAYLCGSFYSKEYANMILQRYRNLNFYAILEEEEYSA
>NZ_CP046703|409936:492313|420234_422880_-|WP_114082669.1|DBSCAN-SWA
MKKLSRAKRYNNLNKKRFWLFSNQKNNVLWLFFACIILSFLLIIKNIPAVANEPILLGSEQVVKQRPNSSELLQQGKKYYQSGQYTEAARVWENALKFYQSQNETISQVQVLNYLGLAYKDLGKIPQAHTAIVESINIIKNFKNPDTKSTLLLAQALNTQGTLQLLQGQTDTAIDTWKQAAVTYERTGDKTGKLISQINQAQGLQTLGQYRRAKTLLEELVTELQNQPDSLLKAQGLRSLGIALQTVGDLKQSKIILDKSWQISKQFNSPTDVSAVLFSIGNIARDLEEYDVAWTYYQQAVNLASEAQAKLEAQLNQLSLLVKVQNGESAQALIPEIETNLAQLPPSRPAIYAKINFAESLMDLKPAGEGIKALLDTNAVKISHLLATAIQQAKEIKDPRAEAYSLNQLGKLYQENNQLADAATLTQQALTIAQEINAPDLVARAAGQVGAIAKEQGDSNSAIPAYEIAFNNLQSLRSDLVAINRDVQFNFKESVEPIYRDYVSLLLQKDNQSNLKQALQVMEALQLAELDNFFRDACLDNSNPVVLEKIDLHAAVIYPIILSDRLEVILSVPNQPLRHYSTQLPKQQIEATLKQLYSSLSPGYPSNERLRLSQEIYNWLVAPAQATLQKSNIKTLVFIPDSLLRNLPMAVLYDGKQYLIENYSVVLSPGLQLFPQGLQRQKLSVLAAGLTEARQGFNPLPGVTEEIKEVTTEVNSQVLLDKKFSRDSLKAAIANKSFPIVHLATHGQFSSNPEETFLLTWGDRISIQDFDLLFKNRSQTNVEPIELLVMSACQTAVGDNRATLGLAGFALRSGAKSTLASLWSVSDESTSSLMKEFYHQLSNQKLNKAEALQQAQIKIMANPLYKHPYFWSSFVLVGNWL
>NZ_CP046703|409936:492313|477131_477332_+|WP_114082694.1|DBSCAN-SWA
MAEQKKQKSDNQETTPTASGGYQTPIDESIRKTGDAEKSDAKPSATPEAPGEDGIAGSPNQGTESR
>NZ_CP046703|409936:492313|416983_419077_-|WP_114082667.1|DBSCAN-SWA
MWQKLKKSLKKWQGTLIITPCVAGLVIAGSNIGVFRILEWVTLDQLFRIRPQEAIDKRIVIVTIDEPDIQYVKQWPMSDRVMAKMIHNIKAQQPRAIAIDIYRDLPVEPGHAELVKEFQNTPNFIGIEKVAGKPVAPPPILAKQSQVAANDLLLDTDGKIRRGIILLGKPDQSLAQGLGVKLALIYLEKAGIELKSINADKQIYGLGKAKFVPLSSNDGQYNEADMGGYQVLINYRGGLESFPHISMTDVLENRIPANFIRDRLVLIGAKAPSLNDSYSTPYNSNLFFPTELVPGVVVHANLTSQILSAAIDGRPMMRAIVKPLNWFLIIFWSGYSATFGTIYIKKRWLTIGGLLLAVVIIFSSAYIAFLGGWLIPVFTPLLTVISALIIGLVQVLWKNLMLSYRQLEDYAHNLEIKVQERTAELAEANEEINILNEKLKGENLRMSAELDIIRRMQQMILPKPEELEAIEGLDIAGFMEAADEVGGDYYDVLHTDGVVTLGIGDVTGHGLESGLLMLMTQTAVRLLKEIRESDSVRFFDTLNRTICKNVQRMNSEKNLTLVILNYAQGQISISGQHEETIIIRKGGQIELIDTMDLGFPIGLDDDITDFISDITLELQPGDGVVLYTDGITEAKDINKNQYGLEPLCEIISHNWHKSASEIKDAVILDVRRHIGKQKVFDDITLLVFKRQEEVSES
>NZ_CP046703|409936:492313|488326_488725_-|WP_114082703.1|DBSCAN-SWA
MTKLQISSPSETIIDAQKYWNATGIFLEIGASYKFEVQGEQFWYDAKIRSDADGYTKPWLRWAKMFRRKPNENWFSLIGNIGQSAEQEFLIGKKLEKYKATSSGELFCYANDLPIMYFNNHGTLILTITRLS
>NZ_CP046703|409936:492313|485661_488079_-|WP_114082702.1|DBSCAN-SWA
MDAEAALAWLDATIPPQTGERLSDLQKVILVQVWLGRKYLDIAHSYGCTEGHAKDAGSQLWKLLSKVLREKITKSNCRATLERVLRKTTAISSSLIDYSRSPHPTPKLEDTNFIGRTEAIAHLNNLVNQGSKVIVIQGEGGLGKTTLAQQYLHQEFDLVLELLMAKETQNITPAERVVEEWLKQDFEQEPGVEFGVTLGRLKRELHNRRIGVLIDNLEPALDQQGGLIASHRNYVELLRVLADARVQSVTLITSRDRLCEPGLNVNHYRLPGLDQSAWQKFFSNRGLVIDSPTLQIIHRTYGGNAKAMGILCGSIQEDFGGDMVLYWQENHADPLAATDLKNLAVSQINRLQALDPQAYRLLCRLGCYRYQDIPTIPSQGLFCLLWDVPPDQHRQIIASLRNRSLVECDKGEYWLHPVIRAEAIARLRPSNEWEIANHKAAEFWTASIKQIETFKDALQALEAYYHYIEINEFEFAGKVILKSRNNQWQQFLPLGSTLYRMGLIQPILAAINQVVNNLENNQNLSELYNILGDLYWITGKISQAIACQEKTLTLATKALKSLIPQPENKHPVYYLRMLEVDSLLSIGLYKIDLWELEAAANLFQQVIYLAQNTEHHRWAEKASVCLALVYSYLGLRDASFALADVAYQNITNEKLVEQTGRFVYFMQILGQTYVNLGEFYQANKILHQALTFAEESHYMQVKAKTLNGLAEINRQQADFELALAHHREAIELLDKIGAKCDLAEAYYQLGLTYQKMAKPDESKLNFNQGIQLFTEIKAPKQVEKISISQSGLFICVSRQCNSDNI
>NZ_CP046703|409936:492313|483990_485055_-|WP_114082701.1|DBSCAN-SWA
MRPYTAILIVPTGIGAAIGGYAGDALPVAKVIAQVCDRLITHPNVLNGASLYWNLPNTFYVEGYGLDKFASGWWGLRPVRNNKVGLLLDQAIEPELRLRHIQAADAVRATLGLTLTDYVITDAPLNVELRTTASGASWGTIGNPDSLLRAAEILIKKAGAEAIAVVARFPDDMDSEAVQKYRQGEGVDPLAGAEAVISHLLVRTFQIPCAHSPALLSEPPQADLSPRSAAEELGYTFLPCVLVGLSRAPQFIIDKGAIASEKGDIWADEVDAAIAPANACGSSALLSLSQRQCQIITVEENKTLIKVPPQPLGIKVIQVNSYLEAVGVLVAHKAGINPSALRPKLSPLQPVIKS
>NZ_CP046703|409936:492313|413784_415389_-|WP_114082664.1|DBSCAN-SWA
MLNKFLPFETNTWAFVVSSLLITFVGGILLYVILFYVLRSIFRKFERDIALVTLNVSAYPALATFVLGVLKLTFESLPSGTVIDSFENIITAGIIISISYWIVQIFIEVFIYYLKQYTQQTEAMWDDVLLPLLEAVVPVVIYLIAAFLVLRSFGVDLTGIWVALGGATFVIGFAAQGILANFFSGVVLLIDTPFQFGDVLRLEDGSIAILRKIGVRVTQLYVPDKHYNIYIPNSNLQSQNIINLSRPTAYYHHSSQVEVLVKYDMYEAKQMIVKIILSHPDTLGDIDKKLEIFDDYYQIDELTEQQKIGKLRLIAEQEVNYKLEEIQIGLETLVVTLQFAEKGGLTQDEINNVQQEYKDILALIGLEAIAEAQNNRTIFNLQEIRVQDSLIELVREWYRIWIRDPNLLDNDSYMVSEEWERKLNLLKRRSQRLYQKISNPQSEETRIDDYVMELNKWVRERFKEPRQKWQEPQVLIKGTNHSDDGITYAEFKLNFFVDDIKLENGRRGDRVSSQIYQEVLQYLKSKCVNDINIA
>NZ_CP046703|409936:492313|472811_473780_-|WP_114082689.1|DBSCAN-SWA
MTYLETAAQFYREVAETPQVGLCCVQSTPLQLPGLKIPLAMQEMNYGCGTTVHSSELGNQPTVLYVGVGGGLEALQFAYFSRYAGAVIAVEPVGAMREAAARNLEIAAQENPWFDTSFVEIREGDAFNLPVADASVDIVAQNCLFNIFEPEDLNRALKEAYRVLKPGGRLQMSDPIATSEIPAHLQQDERLRAMCLSGALTYQEYTELITNAGFGQVEIRARRPYRLLDSQTYNLDEHLLLESLDSVSFKVDIPEDGACIFTGKTAIYAGSEPFFDDSAGHLLQRGIPAAVCDKTAAKLAAIKPAEIIVTNSTWHYSGGGCC
>NZ_CP046703|409936:492313|482402_483149_+|WP_012408581.1|DBSCAN-SWA
MLLHLSTWQEVEAYLQQSKGIIFPIGSTEQHGPTGLIGTDAICAEAIAAGVGDATGAIVGPTINVGMALHHTAFPGTISLRPSTLIQVVRDYVTCLAKAGFSKFYFINGHGGNIATLKAAFSETYAHLEDLQIANAQQVQCQVANWFMCGSVYKLAKELYGDQEGSHATPSEVALTQYVYPEAIKQAPLSPEVASGHRIYSAADFRVRYPDGRMGSNPGLATPEHGKQFYDLAVKELSNGYLEFVNAD
>NZ_CP046703|409936:492313|468282_470193_+|WP_114082685.1|DBSCAN-SWA
MIKTLRSLFSYAALTTIALVAVVTTQLVTTQKTPAIANITPTVIHSFNSSNKSDGSTSEAESVQNSDRNLYGTRYGGGANDKDLIFRVPPNDSNFNLFYLFRDKDGQRTNSKIAATSLYVYVSPTGSDTGGDGSLGKPLRTLAYAAKRVQPNQNYTIYLNAGVYRETEATVLPPGVNIEGAGESSVTITSNGAIPAPGINTGSTDWSLWHYGSIIQLVSPSYSGSSPRYGAPSEMVEATDGNQTLSGFTIDGNGKIIKAGVWVENRNNVTMHNVTFKDFQHSGAVFTRGNMWWFVPLPEGKWMKNTTIHDCTFINSAADGVSGGSTGNLRLGGLDGADIYNITIRENKGYGIKFIHVGHLRNVKIHDCDIQVPEVDSQWSEDASIELWNLSYGNEIYNVTCNTWLSMVNHAVMNDYQPTATHPSNLKMRNVRIKDIDGQSVKESIEVALSGVEISDSYFQDKGFGIAIWGGKAWGGSIENHNINIHNNIFANVARKVQFGFGNSTAVFIPDLATNIKIHNNVFDTLGNSLQLNSADKISIKNNVFLNSQGDDVQGGNNIAFTNNLRRNTNPAKPTWQIRFAANATNIQGDPRFTGTGDRWNSYYKAASSRSLMVDRGTNVGLPYSGSAPDIGRWEW
>NZ_CP046703|409936:492313|475575_476199_+|WP_114082692.1|DBSCAN-SWA
MTDNFFSNKKLLFDRWAPSYDWLFPSVFYRAIHKRLLEYVDLPKSANVLDIGCGTGRLLERLATQFPDLRGTGLDFSANMLRLARQSNHHRPRLIYIEGKAESLPFADGQFNAVFSTISFLHYLEPKQVVSQIARVLSPGGRFYLVDINITSKKEAEPQLLPLTPRGIRLYSPNQRQLLGSSAGLLCLNHHYLLGPVLLTIFAKPPI
>NZ_CP046703|409936:492313|432708_433215_+|WP_114082675.1|transposase|DBSCAN-SWA
MALFPRLLGGGEEIAYGGKGKGVLIHTLTEGNGMPLANSTTPANGNEREQVLPLLDKVKLRTLKRGRPRKKLKVLATDKGYDSKEKRAALRKRGIRPQIPKRVWKTKKNRGRPIKISVPRYQQERCFAWYQRKYRRLVVRWERKKVYFDAFIDLATIHIWIQRILLVG
>NZ_CP046703|409936:492313|483293_483896_-|WP_114082700.1|protease|DBSCAN-SWA
MIEQQKQEPEIPYLTRIQVLGAMGATAIILLIVAKLSLHFGNFSLFSWKWDEKDLLLGVGLGFVITALSGIAYRVWTPYRKSADYYLEVVLKPLALPDLIWLGLLPGLSEELLFRGVMLSALGLDHLAVIVSSFCFGILHFSGSQQWPYVIWATIVGMILAYSALLTGNLLVPIVAHMITNWISSYFWKMWQLRQLKNKF
>NZ_CP046703|409936:492313|430423_432085_+|WP_114082673.1|DBSCAN-SWA
MVEQNFLNTSNNETLPLHELMARILVAEETSSRQILPFMGTMQWLNDYLTPQSFADFVNAILRGIGQAIFVNNPLSGLLILVAILLQSPWMGLMALLGVIASTLTAIALKINPDVIRNGIFGFQGTLVGLALATFGSLANGNGAWNPLWAIAVIILAALTTVLMNTFGVWFTTHFKVSILGIPFHIVTQVFLYLVLLIPQPYFHWGFGIFSVSASASRTLDWLKILASFPISFSQVFFVSNLNLAILVFLAVALCTPIGAGVGLLGCLASAIAALVMGIDPEKIYTGFWGFNSVLTAIAIGGMFYAPNFRSILIAGFSVLICTLCTQLLGLIFNPLGIPFLALPFCLVTIGCFLVVQHSLPSLVPVALYTITSPEEHRLRYLTAKDVISNFRRQLESAIQGTHHRFLFHTADSSLKGNLRYIFDAIDQDHNGTLSVQEFVTHLHKANATISEAELAYLFSRMDIDNSGEIDFEEFGELMLRHRRLMSKYQEFITYFLPIDTDEDESISIEEMNVALSSVGECPLSQDEIIFLQTKTGGNPLSWHQFIEVLLLC
>NZ_CP046703|409936:492313|422952_425973_-|WP_114082670.1|DBSCAN-SWA
MLMKILTSSAAIACILSSTTTAVAQIAADESLGVERSVLSPNVQSTKGNIDRIDGGAIRGSNLFHSFQDFNVGNQQRVYFSNPSGVENILSRVTGNHASNIFGRLGVLGNANLYLINPNGIIFGTNARLDISGSFFASTSNALLFKNGYQFTTQDPKAPPLLTVNVPPGLESWLAPQGAIANSGNLSVGQNLTLVGTNIDLQGQLQAGSNLTLQASNTLKVRDNLNYPFIASAKQQLLAEGNKIDIFALNDPSSGFFSGGNMVFRSANAISGDTQFFSGGNFNLEQINGQEGDLFSFNDPIIRSSGDVNFNSYTGDSIHIFAGGSVRINNINVNRPDTTNFINETVTLSDGLTQVIINGSAQPTVDIRAGTTNFQPTGIKGVINAFSPTPSTDGKPTSADITINQIINSGGLVFLTNQYQPNSSLSGDIRVNFALSTFGRGAKTGNIIIDSRGKIITPQFLTSLGIDYSTFPFLKPGGDITLLAQDDIVMPPSSRIISFGTDGGNITLNSKSAIIQEQAPLRESFIGSFSFGAGQGGDVTLNAPLISLGRSITRTDGKLIITTNSLEANQAKLFTISNRRNASNIIINANSILLNNSNIGSQSIGAGKAGDIEINTSSFVATNNSQIFSRTEGLGNVGNIVVKATNRVLLSGANTGLFANTSLGSSGNNGNIFVDSQQVEIRDGAAISTISQGSGIGGNIEIQGNQLTLDNQALISTKTVSTEGGNINLQLTDSLSLRRGSSILAIAGNETTGGNGANITINTDLLFAVPEENSDITANAFLGSGGNINITTREIQGIGFADTLTPFSNITSSAKKVEVPNLPPEVPSPPPEVPSPPPEVPSPPPEIPNPPPEVPNPPPEVLSPPPEIPNPVLDFSSLESINKPNAAPSSALIGVPNPESDRNNKIVTPSCASTEGNSFTVTGRGGLPADPTATIRGQTILSDTRDFITAQTQNSNQVNSSSTITPIRQQIVEATSLRINAQGQIELIASLPQESLSQKHPNCSDL
>NZ_CP046703|409936:492313|434765_435587_-|WP_114082678.1|DBSCAN-SWA
MLEDLQIAFIGGGTMGEMIMARLLSTKIVPKPDLIIVSDPVSARCLHLESEYGVSTTTCNIEAVVGASIVILAVKPQVLAEVLAILKGKISPDALVISIVSGASIPYLCEGLNHPAVVRTMPNIAVQVGHGTTVWSASSSVTEIQRSHTQVILQALGKEFPTQNEHYLDMATALSSAGTGFIFLYIEAMIDAGVQMGLTRTQAQELTLHTIAGSVELMFQTDEHPAVLRNKVTSPGGVTAVGLYELEKGGMRTLISNAVLAALSRTQQLGTGV
>NZ_CP046703|409936:492313|470693_471683_-|WP_114082687.1|DBSCAN-SWA
MQTQSKITPFKNKLNSPLTKKGISVLQINLGKRCNLACTHCHVEAGPKRTEELSPEVCEQLISLIHKFPEIKIVDLTGGAPEMNYGFKPLVEAARATGKQVIVRSNLTIYFEDGFADLPEYFAQHQIRVVASLPCYLVDNVDKMRGSGVFDSSVKALQWLNQLGYGKDENLILDLVFNPQLPTTEKFSLAPEQTNLERDYKTFLQEHFNIVFNNLFTINNLPVGRTKIHLERRKLHSSYLQFLESNFNPGTVEHLMCRDQLSIDYLGNVYDCDFNQMMNLPAKTGNSEPLTVSKLLEAGSLDLISEIQTAAYCYGCTAGCGSSCGGALL
>NZ_CP046703|409936:492313|429348_430341_+|WP_114082672.1|DBSCAN-SWA
MTILQNQPIPVIIDTDGGVDDALALIMALNSPQLDLKAITVLAGNIHVDQAANNVLRVLSIVAPNTLPIVAKGCEKPLVKPPFNAAGIHGADGLGELDQFKAADGTASYPQLTIEPSTENAIDVILSAAKEYGDRLNIIALGPLTNLATAIQKDAATMKQIGRIIIMGGAVTVPGNITAAAEFNFFVDPHAAQIVMESGIPLTLVGLDVAMKAPLTRQLVEENLQRRPTKVTQFIADCTGIYMAFYRDHEGFHGCYLHDPLAMAVAIDPSLVTTESLYMVVETEGRFTTGLSLADRRDRRDDKSHPPNVEACLDVDTKRFLKLFDKLVCS

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_159402611.1|409936_411158_+|transposase	ISAzo13 family transposase	NA	NA	NA	NA
WP_114082663.1|411331_413098_-	fatty acyl-AMP ligase	A0A2K9KZV5	Tupanvirus	4.7e-11	22.1
WP_159402431.1|413461_413611_-	hypothetical protein	NA	NA	NA	NA
WP_114082664.1|413784_415389_-	mechanosensitive ion channel	NA	NA	NA	NA
WP_114082665.1|415582_415936_-	hypothetical protein	NA	NA	NA	NA
WP_114082666.1|415987_416608_-	ATP-binding protein	NA	NA	NA	NA
WP_114082667.1|416983_419077_-	CHASE2 domain-containing protein	NA	NA	NA	NA
WP_114082668.1|419083_420214_-	DUF928 domain-containing protein	NA	NA	NA	NA
WP_114082669.1|420234_422880_-	CHAT domain-containing protein	NA	NA	NA	NA
WP_114082670.1|422952_425973_-	filamentous hemagglutinin N-terminal domain-containing protein	NA	NA	NA	NA
WP_114082671.1|426919_429352_+	hypothetical protein	NA	NA	NA	NA
WP_114082672.1|429348_430341_+	nucleoside hydrolase	NA	NA	NA	NA
WP_114082673.1|430423_432085_+	urea transporter	NA	NA	NA	NA
WP_114082674.1|432371_432743_+|transposase	transposase	NA	NA	NA	NA
WP_114082675.1|432708_433215_+|transposase	transposase	NA	NA	NA	NA
WP_114082678.1|434765_435587_-	pyrroline-5-carboxylate reductase	NA	NA	NA	NA
WP_114082679.1|435626_436733_-	zinc-binding dehydrogenase	A0A2L2DIY2	Acanthamoeba_polyphaga_mimivirus	3.3e-10	26.7
WP_114082680.1|436781_437579_-	hypothetical protein	NA	NA	NA	NA
WP_114082681.1|437680_439285_-	serine hydrolase	NA	NA	NA	NA
WP_114082682.1|439383_441402_-	ABC transporter ATP-binding protein/permease	G9BWD6	Planktothrix_phage	2.0e-05	22.4
WP_114082683.1|442086_453294_+	amino acid adenylation domain-containing protein	A0A2K9KZV5	Tupanvirus	2.6e-219	30.8
WP_114082684.1|453290_467702_+	non-ribosomal peptide synthase/polyketide synthase	A0A2K9KZV5	Tupanvirus	1.3e-130	27.4
WP_114082685.1|468282_470193_+	right-handed parallel beta-helix repeat-containing protein	NA	NA	NA	NA
WP_114082687.1|470693_471683_-	radical SAM/Cys-rich domain protein	NA	NA	NA	NA
WP_114082688.1|471726_472686_-	inorganic phosphate transporter	NA	NA	NA	NA
WP_114082689.1|472811_473780_-	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_114082690.1|474044_474719_-	response regulator transcription factor	NA	NA	NA	NA
WP_114082691.1|474913_475201_-	nitrogenase	NA	NA	NA	NA
WP_114082692.1|475575_476199_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_114082693.1|476311_476809_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_114082694.1|477131_477332_+	hypothetical protein	NA	NA	NA	NA
WP_114082695.1|478015_478345_+	hypothetical protein	NA	NA	NA	NA
WP_114082696.1|478417_478966_+	GIY-YIG nuclease family protein	NA	NA	NA	NA
WP_114082697.1|479013_480498_+	YARHG domain-containing protein	A0A1V0SDQ4	Indivirus	1.5e-10	27.1
WP_114082698.1|481180_481540_+	nitrogenase	NA	NA	NA	NA
WP_012408581.1|482402_483149_+	creatininase family protein	NA	NA	NA	NA
WP_114082700.1|483293_483896_-|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_114082701.1|483990_485055_-	DUF3326 domain-containing protein	NA	NA	NA	NA
WP_114082702.1|485661_488079_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_114082703.1|488326_488725_-	hypothetical protein	NA	NA	NA	NA
WP_114082704.1|488963_490220_+	DUF839 domain-containing protein	NA	NA	NA	NA
WP_114082705.1|490444_490858_-|transposase	IS200/IS605 family transposase	A0A1L2BWN1	Bacteriophage	5.4e-43	63.0
WP_114082706.1|490924_492313_+|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1L2BWW3	Bacteriophage	4.0e-82	45.6

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NZ_CP046703|553986:640842|DBSCAN-SWA
TTTATTCTGCGGGTGATTCTTGCGCTTCAATGTATTTTCTAAGAGTTGATACGGTAACACCACCACAACTAGCAACAAAATAAGAACCGCTCCAGAACACATCTTTCCAGTAAAAACTTTCTAGGTGTTCTGCAAATTCTTGCCGGAGTTTTCTAGATGATACAGACTTCAAAATATTTACTAATTTGCTCAATTCAACATCTGGATGATATTGAAAAAGTAAATGTACATGGTCATCTTCACCATTAAATTCTACCAGTTTACAATCCCACTTTTCTAGCAATTCTTGCATTACAGTATTTAGTTTACTTAGCATCTCGGATGTAAATGCTTTACGCCGATATTTAGTAACCAGCACTAAATGTACTTTCATGTCGCTAATAGACCTTCCTTTTGAAACAAAATCATCTTTCATATTATGCCTAAGTCAGTGTATGCTAAAAAAGCAACACTTAATTGATCGAATAAGTGAGAATCTCTTATCAGTACCGATTAAAACCAACGAAAGAACAAGCATTGCATATTGATAAAACATTAGATATGCTGCGATGTCAGTATAATTATCAGCTTGCTCAGAGGTTTGATTGGTATGAGCAAAACAGATGCCCTATAGATAGATGCTCACTTGTTCTTTGTCATATCCCAGAGTTAAAAGATAAGCCTAATCGCTTTAGTCAACAGGCAACGCTAACCCAACTAAAAAAAGACAGACCTTGGTACAAAAGCATTCATTCTCAAGTTCTACAAGAAGTTCCTAAAAAAGTTGAATTAGCTTTTGATCGTTGGCTAAAAGGTGATAATACTGGCAATCGTAGCGGTAAACCTAGACTCAAAGGTAAAGGGCAGTATAAAACTTTTACGTATCCACAATTCAAAAAGGAGCATTTTGAAAACGATAAAATAACATTGTCAAAAATAGGTGCTGTAAAAGTAATTGTTCATCGTCAAATGCCGGAAGGGTTTGACATTAAAACTGTAGCTGTTACCAAAAAAGCTGATGGATATTATGTAACTCTGAGCTTAGAAGATAAAACTGTACCGACGGTCAAACCGGATTTTGACACTAACAATATTGTCGGAATTGATGTTGGGCTGATAGATTTTTATGTTGCCTCTGACAATACTAGAATTGCTGCACCAAAATATCTTCGCAAAGCTGAACGAAAATTAAAGTCAGCGCAGAGAAGAGTATCAAGACGCAAAAAAGGCTCTAATCGTCGTAAAAAAGCTATTAGAAAGTTAGGTATCCAGCATAAAAAAGTAGCGGATACCCGTAAAGATTTTCATTTCAAGGCTGCTAACAACTTACTCAAAAAGTATGATGTTATCGCAGTAGAAAAACTGAACATCAAAGGACTGGCTAAATCACGACTTGCTAAAAGTGTAAACGATGCTGGTTGGGGACAATTTATTTCGATACTGACAGTCAAAGCCGAAAACGCTGGACTGAAAGTTGTTGCTGTAAATCCAAACGGCACAAGCCAAGAATGCTCTAATTGTGGCACTAAGGTAATAAAGCCACTATCAGAAAGAACGCATAATTGCCCTAATTGCAAGGTTAGTTTGTGTAGGGATCTGAATGCAAGCCTGAATATAAAAGCGCGTGGGGCACACGCCTTAAAAGCTCAGATAATGTCTTCATTGAAGAGTCTCTGAGAAGCTCGCGCTTACCTGTACTCAGGAAGCGCGAGTATGTCACCCGAAGTAATAGGAAGTGTCGTGAATTGTTGCCCATTCAGGTTTATAAGTGGCAAGAGAGCGCATATATTGGGCACGTTCAAAAGCGCTGGGATTTGGACAATGCTTTTGACTCATACTCCCCTGCATTTGTTGGACTGATTCATATTCATGTTTTTGCATCCATTCGCGCATTTCCTGCTCGATGACTCTAATGTGGTTGATCCCATTTCGTAACAGTGCCGAGCAAAGCATCGTAATCTTGGCACCAGCCATGAGCATTTTTAACGCATCATCACCCCTCTGAATACCACTTGTTGCTGCCAAATCAGCATGAATACGACCATAGAGAATGGCAATCCATCGCAGAGGTAATCGCATTGATTGCGGTGTACTTAACAGTACATTGGGTTCAACATCAAGGAGATTGAGATTAATATCCGGCTGGTAAAAGCGGTTAAATAGTACTAAAGCATCAGCACCCGCCTCATCCAAACGTTTTGCCATATTTGCCATATTGGTGAAGTACGGGCTGAGTTTGACTGCTACGGGGATAGTTACTGCTGCTTTGACTGCACAAAGAATATTAATATAGGTTTGCTCAATTTCATTGCTTGTTAGTTCCATATCAGTAGGGACATAATAAATATTCAATTCCAGCGCGTCTGCTCCCGCTTGCTGAATTTGTTTGGCATAGTTTGTCCACCCACCAACAGATGAGCCATTGAGACTGGCAATAATTGGAATGCTCACCTTCTGCTTGGTTTTGTGGATATGCTCTAAATAAGTTTCTGGCCCTACCCGAAAGCTAGCTGAGTTAGGGAAGTAACTTAAGGCTTCAGAAAAACTTTCAGTTCCTTGAGTGAGGTGATGGTGGAGTTCATCACGTTCTAGGCGCAACTGTTCTTCAAATAATGAATGCATCACCACTGCGGCTGCACCTGCATCTTCCATGCGTTGGATGTTGTCAATATCCTCTGATAGAGGGGATGCAGAGGGAACAAAAGGCGATCGCAATTTCATTCCCATATAAGTTGTAGTTAAATCCATTATGATGACTCCTGTTTTCAATAATTTCTTGCAGCTAAGTATTGATACATCTGCCAACGGGTCTTCACATCTGCTTGAGCTTCTTTAAGTAATTGCTGTGCCGCTTCTTCGTTACTCTTAGTCAACATCTTGAAGCGGTTTTCTAGATACATATATTGCTCTAGCGGTAACTTTGGTGTGCGTGAATCAAGTTGTAGTGGGTTTTCTCCTTGCTTGATGCGGTCTGGATTAAACCGATACAGCAACCATTGACCAGAATCGACAGCAGCTTTTTGATTCTGCATTGCTGTACTCATGTTGATCCCGTGGGCAATACAATGGCTGTAGGCAATAATTAGCGATGGGCCTTGATAAGCCTCAGCTTCTAGGAATGCCTTGAGAGTGTGTTCATCTCGTGCGCCCATTGCGACGCTGGCAATATAGACATTGCCATAAGTCATGGCCATTAAACCCAAGTCTTTTTTAGGCGCAGCTTTACCCCCAGATGCAAATTTGGCTACAGCGGCTTTGGGAGTGGCTTTGGACATTTGTCCACCTGTATTGGAATAAACTTCAGTATCGAGAATGAGAATATTAACGTTGTGTCCACTGGCTAAGACGTGATCTAATCCTCCAAAGCCGATATCGTAACCCCAGCCATCACCACCGATAATCCAAACGCTCTTTTTCACTAAATAATCAGCTAGCGATTTTAGATTTTGAATTTTTGATTTTTGATTGGGGTTTGGTTGATGATTGACGATTTCATCTAGCCGTTTTTTCAGCAATTCTATTCGTTCTCGCTGTTCCCAAATATCAGCTTCATCTTTTTGTTCGGCATTGAGGATACTATTTGCCAGTTCTTCACCCACATCTGTTATCAGATATTTGAGTAATTCTGCGGCAAATTCTGCTTGTTTATCAATCGAAATGCGAAAACCGAGGCCAAATTCGGCGTTATCTTCAAATAACGAGTTTGACCAAGCTGGCCCGCGTCCTGCGGCGTTGTGCGTCCAAGGTGTGGTAGGTAAATTACCGCCATAGATAGAAGAACAACCAGTGGCATTGGCAACAATCATGCGATCGCCAAATAACTGCGTTGCTAACTTAATATAAGGTGTCTCGCCACAACCAGCGCAAGCCCCAGAAAATTCAAACAATGGTTCTTGCATTTGCTGTTGGTTAATATGAGTCAGCTTCAAATGACTTCTATCTGGATTAGGAATACTCAAAAAGAAATCCCAATTTTCCCGTTCTTGTTCACGTAATGGTCTTTGCGGTTCCATATTGATTGCTTTGCGGCGTAGTTCTGATTTATTCTTCGCCGGACAAACATCTACGCAAATTCCGCAGCCAGTACAATCTTCTGCTGCCACTTGGATAGTATATTTAAAACCTTGCCAATCATGGTCTTTGGCATTGGTACTCTTAAACATTAATGGTGCATTTTCTAACTGCTGCGGTTCGTAAACTTTACTACGGATGACACTATGAGGGCATACCATGATGCACTTGCCACACTGAATGCAGACATCTGTATCCCAAACGGGTATTTCCTGGGCAATGTTACGTTTTTCCCATTTCGCTGTACCAGTGGGATAAGTACCGTCTGCTGGTAAAGCGCTAACAGGTAGTTCATCCCCTTCACGGACAATCATTTTACCAAGAACATCACGGACAAATGGGGGTGCAGCATCAAGAATTGGAGATTGTTTTCCTTTCCCATTCCCTATTCCCAATTCCCTATTCCCCACTTCAAACAAATTTTCCAAAGTGGTATCTACTACTTTGAGGTTCATCTGCACAATTTCGTCGCCTTTCTTGCCGTAACTCTTGCGAATAGAGTTTTTGATTTCTGCAATCGCTTCTTCTCGTGGTAGTACACCCGATAAAGCGAAGAAACAAACCTGCATGACTGTGTTGATTCTGCCAGCCATGCCTGCTTGACGAGCAACTTTATAGGCATTAATTACATAAAATTTCAGATGCTTTTGAATAATTTGTTCTTGTACTGATGGCGGTAGATGATTCCAAACTTCATCCTTTTCATAAGGAGAATTAACTAAGAATGTTCCACCTGGTACGATGTCTTTCAAAATAGGAAATTTTTCAATAAATTCCCATTGGTGACAGGCAACAAAGTTAGCTTTGCTGATTAAATAGGTCGAGCGAATTAATTGTGAACCAAAGCGTAGATGCGAAACTGTGACGGAACCTGATTTCTTGGAATCGTAGACAAAATAGCCTTGAGCATAATTGTTTGTTTCTTCTCCAATAATTTTGATTGAGTTTTTATTAGCGCCCACTGTTCCATCGGCACCCAAACCATAAAAAATCGCCCTTACCGTGGTGTCTGGTTCAATACTAAAGTCAGGGTCATAATTCAAACTGGTGTAGGTGACATCATCATTAATGCCGATAGTAAAATGATTTTTTGGTTCAGCCGCAGCCAGGTTATCAAAGACAGCTTTAATCATTGCTGGCGTGAATTCTTTAGAAGATAAACCGTAGCGACCACCGACGACTTGAGGCAGAAAGTCAGCACTTCGGCTACGCTCAGTGACCGAGGGGCGGAGGGGCAGAGGGGAATCTAATCCTAATTTTTCCCCTGTTCCCCATACTTCATACAAAGCTGTAACTACATCAAGGTAAAGGGGTTCACCAGATGCGCCTGGTTCTTTGGTGCGGTCTAAAACTGCAATGCTACGGGTAGTTGCTGGTAAAGCGGTGACAAATCGCATCGCATCATAAGGGCGATATAGTCGTACTTTCAAAACGCCTACTTTCTCGCCATTAGCGTTGAGGTAATTGACTGTTTCATGTACAGCCTCACAACCGGAACCCATCAGCACAATGACTCGTTCGGCTTCTGAGTCGCCGTGGTATTCAAATAGTTGGTATTGTCGCCCAGTCATGGCAGCAAATTCATCCATGACTTTTTGGGTGATATCTGCACAAGCTAGATAGTAAGGATTGACAGTTTCTCTGGCTTGGAAGTAGACATCAGGATTTTGTGTTGTCCCGCGCAAAACTGGTTTATCGGGGGTGAGGGCACGTGAACGATGGGCGAATACTAATTCATTGGGAATGAACTCTCGCAAATCATCTTCTGTTAAAGTTTCTACTTTGTTAATTTCGTGGGAGGTACGAAAGCCATCAAAAAAGTGGAGAAAGGGTATTCGTGATTCTAGGGTTGCGCGTGTTGCTATCAAAGCAAAGTCTTGTGCTTCTTGCACTGATGCGGCACACAACATAGCAAAACCAGTACCACGCGCTGCCATGACATCGCTGTGGTCGCCGAAAATGGAGAGAGCTTGTGCGGCTAGCGATCGCGTGGCAATATGAAATACTGTAGGTGTGAGTTCTCCGGCAATTTTGTACATATTGGGGATCATCAACAATAATCCCTGCGATGCTGTAAATGTGGTTGTCAGTGAACCAGTTTGCAAAGCACCATGTACAGCACCAGCCACACCTCCTTCACTCTGCATCTCTACCACAGAGGGAACAGTACCCCAAATGTTGGGTTTGCTTTCACTAGCCCAAGTATCTGCCCACTCAGCCATTGGTGAAGAAGGTGTAATGGGATAAATCGCAATGACTTCATTAAGTCGATAGACGACTTGGGCAACAGCCTCATTGCCGTCTATAGTTGCAAAGCTTCTCTTGTTCATTTTCTTGCACCTGTGTCTTTAAGGGCTAGCAATGACTAAGCTGGATCTACTTTTGACATTAGGATAAGAAGTTGAGAAACTTGTGAAGACTCACCTTTGGCTATGATTCAGTTTGTGCACATAATTCTTACTTTGTCAAAGAAAACATAGCTGTTAACCAGGAAATCTTTGCTAAGAACATACTGGCGTGACTATTAGAAACAGTTACAGAATACACATATTGTTTTTAAATCTGGAGGGAGCTTTCTGAGACGAATAAGCCAATCCACTGAATTGCCGGATCAACATCACGCCCCCCACCGCCTAAGTCATAGACCATCCCAGATAAGAGTGGATTCAATACTTTTCGGTTAAACCCAATAATCTCTTTTTTGGTCTGGGGAAAGGTTAAAGGGGAATGGCACTAAGAAAAGCTGAAACCTCCTTGCTGGCATGGTGTGGGAGGTGTGGGAGGTGTGGGAGGATGGGGAGGCAATGCAGCATTTGTTGATATGCAGTTATTCAATTTCTCCTCTTTCTCCCCACACTTCCCCCACTCCCCACACTCCCCACACTCAAAAAGCAAGTTATATCAGGGCTTTGCGATCAACAAGCGTGCCATTCGGTTAAAGGGCAATGGGGAAAGGGAAATTCAAACCCTTTCCCTTTCCCCTTTCCCCCTTAACCGAAAAGTATTGAGAGTGGATTCACATCAGCAGGATTACTTTTCTGGTATTGCATAACTCTGGCTTGTGCTGATGTGGGAAAGACAGCGATCGCAAAACAGAGAGTCAGGATGAACACGCATAATGATTTTGCTAGATATTTAAATCGGTTCGAAGGAGAATAACTGTTTTTCCTGTTCACCTTCATAGTTTCCTCCTATTCTCCTGGTGGGAAATCAGTCAGTTGTTTGGCATCTGCGATCGCAAAACCTCGGCTTGACCTCAGGGATAATTCGTCAGAATCAAAAATTCGGATGCTGAAATCGGTTGGATTTCAACATAGGCAGTCCCATCTTGTTGCTGCACCAACACTGTTGATCCCACTTTGTGAGGACCTGTGTAACCCGGCAGATTTGCCATTTCAGCCGTATTCAGAATCACCGTCATTGAACTTTCAATCGCGTTCAGGTTGGCATCTACCAAAACTCTTGCTCCCCGATTATCCGTTCCATGACTGTTCAGCACACAAACCGCCTCTTCATCATCTAAAACCCGTGACCAACCGATAATTTCCCCACTCCGTCCGTGATCACCAAAGGGCAAGTTTAAGAAGGGAATCGCGATCGGTCGCAAATACTGCCGTCCCAATCGCAGCACTGGGAACTGCTTACGGATTGCTGCCATTGCCTTAATTCGGACATAGGCAGGGTGATTTGGCTCGAAACAATGAGCACCTGCTGTCCCAAATGGCCCGAAACCAGGTAAATTTTGATCTAAAGCTTGCAGTCCCGCTACGCCAGATTGTCGGGGATGCTCTGGGCCAAACATCGCCTCCCGTAAATAGCGATCGGATTTCTTCCAGTCGGGCAACCACCTCCGTTCAGACGGTTCTGGGCCTGCCAATGCCTGCTCAGTTCCAGCGTAAATGCAGGGCACTCCCAATGTAAACAGTTGCAATGCTACTCCAGCAATCACCTGATGATCCGATGCAGCTTCACTGGAAAAGCGGATTTTTTCACCAAATACATGATCGTGATCATCCAGAATTGAAACATGCCGCCGTCCGATATTCCGATGCGACCCCATTACAGCTTTCCCTGGATCAAACCCGTTAAAGTAGGCTCTTGGATCTATCAGCCCTTTGGCAACCAGGTTAAGATTTACCCGCATCTCGGCGATATCCAGAGCAGCGTTTAGATTTTGCCCCACCACATCCAGATAGCGGTCTTGGTTATAGTCTCCGCCTGCTATTTCTCCCACTAGAAAGAAGTCACTCTTACCTAGATTGGCTGCAAACTCCTTAATAGTTCCGCAAAAATTTCGGGCTTGTTCATAGGTCACATGCTTGAGTGTATCAATCCGAAAGCCATCACAGTCCGTCAGCGCAATCCAGTATTTATAACATCGGGCTAAGTTATCTAACAGATAGGAATACTCCAACTGGAAATCTCGTAGTGTGATAAAGTCCGATCGCCGGAATTCGGCATTGGGATCATCCAAGTCTCCTCGCCCCAAATCTCCCTTGCCAGCACGAGTGTAGCAATCTGCTTCCTGAAGTTCCCTTGGCCACACTCCTTCTGCGCTCGTTTGAGGCTTTACCGCAATGGGTTGTCCGCGATCGCCTAGCCATGAGCCAAACTGATACCAACCAGACGTATAAGGTGGTTCCAATTCTCCCCCAGGAGTATCCGGAGCATAGAGCCAGTTAGATCCGGAATGGTTAAAAATGATATCCAGGATAATGCGTAGTCTCTTTTCGTGGGCTTTATTGACCAGACTGACCAAATCTTGGCGAGTCCCAAAGCGAGGATCGACCTCTAGAAAATCTTGAATGCCGTAACCGTGATAGCTATCCAAGTGACCCCGTTGCTGAAAAATTGGCCCTACCCAGATCGTTGTTATGTCCAGTTGGTTTAAATAATCCAGCTTCGACTCTAATCCTTTGAGTGTCCCACCCTGCCAGCGATCGCCTCCCGACTCTGCCCATTTATCAAATTGCCAAGACTGCCCATTCGGTAGACTAGGGCGGGCCAGATTCAGTTGCTGTCGATTCAGCAGAGGACGTGTATCTTCTTTACCATCGCTAAAGCGATCGGGTAAGAGAAAATAAAGCACTTCATTTCTCCAATCCGCAGGGGAGGGAAAGTAATTTTCGCGTCGAGGTAAAGAAAAGTCTTGTAGACTCTTCGGTCGCTGTGTAGCTAAATTTTGATCAACAAATGTCATAGGAATTATCTCAACACTAGTAAATAAGTTTACTCAGTGGAACTATTTTCTGTTTCGACGAAGACTATAAATTTTCTCCGCGACTTACTTAGTTGAATGACTAGCTATGTGTTGCAACGCGGTAATACTAGGTATAAAACAGTAAGCTCCTCCTTTGGTTGTGATGAATCGATCAAAACCCGTCAACTTGATTGAGGGGTTGTCTGGGGAGACAGGAATATCGAATTGACCACTTTTATTGTCATTAGCACCAATCAGAGGAGCTTTAACATCTGTAGGTAAACCAGCAAAATCTCCTTTATTCACCCACTCTTCCATGACAAATTCAAATTGACGTTTGAGATTCACACAGATGAATAGACCTAGCAATCCCCTTTCAATGCCATCATTAGGAGAGTTAGGATTATAAAGAGACCCATAGGGAATTCCCCTACGGATGAGTCTGTGAATATTTGTTACCCCTTGTATTTTTGCCGCACGAGGATTTGTGCGTCGTATATGTGAACCAATCGGACATTTATATCCTTGTGGATCATCAGAATAATCAAAATTATTAAATTGTTCGTAAATAATTGATTCTTTAGGAGAGGTTAGTTGATCAGCATCTGGAGAAAGGTCTAGAGGGACACCATTGCGCCATCGGCCACACATTTTAGCTGCCAGTTTGTCTGAATCAATTTTATCTTTTTGCTCTTGGAGAAACTTTTCAAAGCCAGCTACATCTTGTTCTAGGACTCGAAAAGCAGCAAAACTACCATTCAAGCCCAACTCCGGAGGTGTCGGTACGTAGTAAGGAGCTTTTTCATCATCCAGCAGGATAAACTCATAAGCAGGAATAATAGGTTGGGGGTCGAGGGATTTTGAAAGTCCACGCTTTGTAGGAACACCTTCTATTTTCGGCTGTGAAATTCCATCTTTGTAACCAAAATGAACTATATCGCTGGGTTGGCCTTTCTCATCAGGAAGTTTAGCTCCATCAAAGCAAGATAACTCTTTAAGTGCGTCTCCTTCTTTAAAGAGCGATCGCAGTTTATCCGATTGCTGCTCTAACACCTTACTATCTTGAGCATAGAGCGAGAGCAAAACATGAGTATTAGATGTTCCTAATCCACCTTTCCACTTTTCAGGGACACTCTCTCCAATATCACCTACTTGAGTTGCTTGAGCAATAGCACCTTGTCTAAATGATTTGTAGTTGGAACCGGAAAAGGATTTACCAATATCTGCAACAAATTGGAGAGCGTTTAAACCTTCAAAAGTAAAGCCAATATTTAAGCAATAACTCGGTTTTATGTCCCACCATGCAGCAGTGGTGATCTGAGGAATTGATTCATCACTACCGCTTACCAAGCTACCAATAAATTTCTTTGCGCCCTTCGCATCTTTAATATATAGAACAAAATGTCGCACATTGTTCATGTTATAGCCACGGATAATATAACCCTGGATATCACTAAAGTTAAGCTGCGTTAGAGTTTTTTCATTTGTCATAGATTTTCTCATTTTCAGAAGTAGGATGTTTGACAAATGGAGAATTATTGCCTTAAACTTAGCGACAAAAAATCTTACATGTTCTGCCTTTTTGCTCAGTCCAGTTCTAAATAAAAGCGTTGCCAAATAGAATTTTTCAGATTAATTAACTACAATTTACTCTAGGGGTGTGGTTGCCACTAAAGTAAGTTTTAGTTTAAAGGATGTTTGAAAAGTCCTCTTGTCAGTATCAAAAGTTTTGATCCTTCTAAATTACCCGATTAATTGGGGGACTTTGATTCCGGTTCCCCCCGATTTATCGAAGGGTTAGGGGGGATCTAAAAGTGCATAAAGTCACAGTGAAACACTTTCCAGATAACCTCTTAGCAGTTAGACGCAAGCTGACGAATTTTAACCACACTTAAAGTAGGATAAGCACTATACCAAACTTTTACTGGTTGATTATATTTTTTTATATAGTCAGCAAAAGCTTCAGAGTCTTTTTGGACTGGAATTAACCCCTCAGCATTTTCTAAATGCACTAACACTGCATTGAAAAAGTCACCAACTACTGCAACAAAGTCATCAACATATTTATTAAAATCTCCGTCATAGGCAGTAAAGAGTGCAAATTTAGCATAATACTCTTCCCCTGATTCTGGCGTAACTTTTTCGAGGAACATAAAACGTCCAAAATGTACTGTGCCAATCTGATCTAGTGCTGTTCCAAAAGTCCCAGTTTCTAAAATGTCCTTTAGGGCTTTATAGTTTTCTAGCACTGGGGCCTTAATTGGGGCAACAAAGCTTAATGGACTTTGTTCTGGTTTAGTACTCATGATCATGACTCCTTAGTATTTTTAGAACTGAACGCGGGTATTGCTTGTTTTGGCTATGTCAATTTAGTTTTTATTAGTAAATAAGATGCGTTTCTCGTGACCTTTTAAGTGGACATACAAGGGCAAAGTTTTGGCTATTTAATAGTCTGCTTTTTACGCTGTACTGTACTAGACAGTAAGGGGCTAATACCGAACTTTTCCAGCACCATGTCGGACGTTTGCAGTGCGCCTTCAACCCAACCCTGAGCGTCTGAATAGGCTTCACCACAGATGTAGAGTGAGCAATCAGTGCCGAGCGGTTGGATAATTTGTTGCTTCACCTCCCAACTTTTTACACCGATATTCCAACTATTCCATCCACCGCCAAACGGGTCATCACCCCAGTCGCGGAATGCGGCGTTCTGCACATCCGGTGTATAGTTGAGACCGTGGATGATCCCAAGCTGGCGTGCCACCTCCTCAACCATCGGTGCCGGTGCCACGTATTTGTCCCATTCGCTGTTAAGCTTTTGCTTACTTGACCCCAGGTATGGATTTTTCACTAATTCTGCAACCTGCCGATGCGCTTGCCAAGCCTGATGTCGTCGTGGGCGGAGACCGTCCCAAAAGCCGATGTCTGTGCCATCATCATAACTTGCCATCAGCATCGATAGCCCCTCGGTGGCTGGTTTGCCGTCATCCTTGGGCCAGTAATAGGTTTGCCGCACTGGCAGGTCTGTGACTGTTCGTCCAGACTCAACTGGAATGAACTTACCATCGTCTGTGTAGCCTGCTGCACGCCACCACGGGTTAGTATAGGTTGTGAAGAGCTTGAAGAGTGGGCGCGGTGTGACGCTAGTGATGAGGTGCTGAATCTCCAGCATAGGAGGACTTGTAGGCACAAGCAGATCGAGTGAGCGGCGCGGCATAGCGAGGATCAATGATTTTGTCGCGATCGTTTCTCCCTCGATGCTCAGTTCAAATGTGCCGTTTTTCCAATCGAAGCCATCGAGCCTAGTATTGAGCCGAATTTCGCCACCAGCTTTGGAGAAAAGCTGCGCTAATGATTTGGGTACCTCCTGAAATCCTTTCTTAAAACCCTTGTATTGTGGGTCAATGCCAAAATCGGAGAGATACCAGGGAATTGCATCAGCGGCATTCCAGTTAGTGAGTGTTGAGTTGTAGCCGCCAGCATCGATGCCAAGCTCGTAAGCTTCACCGCTAATGATGCGTATTAGCACGTTCCAAAAGCCTTGTTTCCATAGCGGTGTTCCAGCAAAGCTCGCGTTCTGCGCCATCTCTCGGCGTTGAGATTCAGTAAGCTTTGGATTTGTGATTCCCGGTACAATCTGCTCAATCGCATTGATGATGATGCTGCCTGCTGTACCACCACGTTCCAGAAACGAGAGATGATACGGCACTTTATCCGGTTTGATAGTGAAATCGGAAAGCCGAAGATAGACACCACGGAGATAGGCGATGTTTTGTGGTTGATCGACCGGAAAATCATACAACTCAATCTGCTGCTCTAATGGGAGGACTTTATTAAGCTCTCCGATGAGCTTTGCGATCAGTGGTTGCACTGTTGGGAGGATACGCATCCCCCCAAGTTCCGCAACCATGTTTGAAATATCGGGCGGCCGCACTGAGAGCAAACGCCCCCCAATGTAATTGCTCCCCTCGAAGACAACGATATTTTGATCTGGGTAGGCTTGTTTGAGCCGCCACGCATTATAAACGCCTGATACACCACCACCGACGATCGCAATATCGATTTCTGCCATGATTTGTCATCCTCTATTGGTGTTTGGTTTAAAAAATAATCGGAACATTCACCGCTGCGCCAGGAGCCTGCGTCCGCAAAAATGATTTTTCCACCTGACGATGAAAAAAGTTGAGTGGCGGTTGTGCGGTATAGCGTGCAGACATCTGCTGGGTCAATGGCGTTGAAAGCGTGTCTTTGGCAGTTCGTACATCGAGGATATAAGAGCGTCGGGTCTTCAATACATAATCGATACCGCGCCGTACAGCAGAACTAACGTCCTGGGAAGTCTCTACAATCTCACCATCTTGACCACCGAAGGCCTTCGCCAGAGCTACAAAGTCGAGTTTTGGCCTCTCAATTCGCAGATACTCAGGGTCGTTAGTCTTCGGTTTCCAGCCATAGCCAGGTGCAGAGCTATATGCAGCGACAACCTGTTGCAGTCCGCTTTGCAGTGTTTGGTATTCCTGATTGTTCGTAATGATATAGAGTATGCCGAGTTCGCGGTGTGCCGCAGTCCACCAAGTTTGCGGATAAAACAGCGATGAGCCGTCACCGACGGCGTTAACGACCAGGCGCGTCTCGATGCCTTGCCAACCAAAGCTTTCGAGTTTAATTCCCAGAGAAGCAGGCATTGACCAGCCGAGGGAGCCACCAGCTACGCAATAGTAGCTAATAGGTACGGCTCCATCATTGCCAAGTGGAAGAAAATACTGGAACGGTGCTGGATCGGAGACTGCCTCATGGACGTACACAAACTGTTTCTCCAGACCGCGCTCCTGAATCGCCTTGCGGAGCGCGTCAGCAATGACAACAGCCCAAATCTCATCTTTTGTTAGTGCTAGTTCCAAATATTGTTGCCACTGTTGATGTCGCTGGACATTGAGTTGTCGCAGATTCTCGTTGCGCTTTACCGCCTCTGCCGGGGGATTCTGACGAACAAGGTTGTTGATCAGTGGGAGTGTTGTTTTGATATCGCCGAGAATTCCCACCTGGCTATAAGAGTTCTTGCCGATGTCCCAGGTGTTATTCGTCAAATAAATCTGCTGAACACTGGGTGGAATCAGAGGACCGTCGGAATACTTGAAGACTGTAATCTGAGCTTGAAGACCGAAGCCGCAGAAAAAGGCAACATCATGATCCTGAAATACTTGCTGCATTCCTAATTGGGTACCAGGGAGTTCTCCCTGCCAATGGAAGTCATCATTGGGGAAATTCGCCACGCTACTGAAGGTCTGGAGTAGTACTGGTGCGCCCAGGAGTTCTGTCAGATCCTGTAACTCTGGCCAAGCATTAGCATAGCCAACCGCATCACCAGCAATGATAATCGGGTTCCTTGCTTCTGCCAGCAGCAAAGCCGCTTGCTGGATTGTTGATGAGTCACCAGTGAAATGGGGCGATATCTGCGTGATCCCTGGAATCCGATCTTCGGCATCAATGTGGCGCATTGTAAATTCCCACGGGATGGCGACCATCACTGGACCGTTAGGCGGCGCGATCGCCTCTTTGAACGCACGCTGTAAAACCAGCCCAATTTCCTCGGGTGTCCGAACCTCATGTGCCCATTTCGTGTACTGCCGTGCCAGATCAACGAGGTTTGAGGCCAAGAGTGGCTCTTGTGTTACTAACTCATTTTGCTGCTGGCAACAAAGTATTACTAAGGGGACATGCGATCGCCAGGCGTTGAAAAGATTACCGATGCTATGAGCGATACCCGGTGTAACGTGGACAACAACAACGCCTGGTTTGCCGCTCATCCGTGCCGAACCCATCGCTGCACCGATGGCGATGTTTTCATGCAAACATTCAATGTATTGGACTTCATTTTCTGGATATGATGTGCCATCAATAATTGGAATTTCGTTTGTACCTGGTACACCAAAAATGTAGTGAATGCCTATCTGACGCAGAATGTCGAAGATGTAGTCGCGAGTCCAGCGTTCTGGGTGTTGTATAGTCTTATTTGTCATACTTTATTATGCAGATTATGCCAAAACGGTAATAAATCAAAAACGCAAACCTGATTTTGTCAGCCATAAATCGAAGAAATACAGCTCCGCTTCTAAAGCACGCTTAATATTTTCTGCCTGCCGAAAGCCGTGCTGTTCACCGTCAAAGAGAAAATAACCTACAGGAATATTTTTACCGCGCAACGCCTCGACGATTTTCTCCGTTTGGTTGGGAGGAACAATTCGATCTTCATTGCCTTGAAAAAATATCAGGGGCGAAGAGAGTTTGTCAGCATGATGCACAGGAGAGCGTTCTTCATAGAGGTCACGTCGATCTGGATAAGGGCCAATTAACCATTCGAGATAGTGCGACTCAAATTTGTGCGTATCCCGAACCAAAAGCTCTAAATCACTAACGCCATAAAAACTGGCTCCTGTTTTAAAGAAATTGCGAAACGTTAAGGCGCTTAATGTTGTATATCCACCAGCACTTCCTCCTGTTATAGCTATCCGTTGGCTATCAACTAAATTTTTTTGAATGAGATACTTCGCTGCATTGATACAGTCATCAATATCAATAATTCCCCATTTTCCTTTCAGGCGATCGCGGTACTCCCTACCGAATCCAGTGCTACCACCATAGTTAACGTCAACAATTGCGATCCCTCGACTTGTCCAGAATTGTTTTGACAAATTTAAAGTATCGTCAGATGCTGCGGTAGGACCACCATGACACATCACTAATAGAGGAGGTTTACTTCCAGCAGGTGCAATATACTCAGGATTTTTGGGAGGGTAAAAAAAGGCGTGCGCTGTCAACTCTTTCTCAGTGGGGAACTCAATAGCTTCAGAAGTAGAAAAATAAGGTTGCCATTGCTGGTTTTCTTGAGTAGACCGACGTAGGATTTCAACTTCGTAAGTCTTTAAGTCAATCTGAACTAGCGCCGAGGTCATAGTGGGTGAACCTGCAATAGCCACAACCTTTCCGGGTGTAGCACGAACAGCTGTGAAATAAGTAAACGGTGTATCGATAGGCTTAAGCAAACCCGTCAAAAGGTCAATGATTCCTAGTATCCACCTTCCTCCTTTTGCATAAGTGCAGACGATATGGTTGGCAGATACAAATGCATAGGTAGAAGTTCCAAACTGCCAAGGAGGCTGACCGAACTCAGCCTCATCCAAAAGAACTGGTTCAACTTTGCCATTCACAAATTTATAGAGGTTCCAGTAACCGCTCCGGTCAGAAATGAAGTAGAGTACACCATCCGGCGACCACTTTGGTTGTAATATTGATTCTGCTGAACCACCTGCAACTTTTTGTGAGTTCTCCAGTTTCCCCTCATCTGTGCAATTAGCAATCCATAATTCTGTGGCTACCCAAGGCATATTTGGATGGTTCCAGGTTAGCCAGGCAATTTGCTTACCATCATGAGTCAGTCGAGGAGATGAATAAAAATCATTACCTTGAACTAGAGACTCCAATTTCCTACTGTCAGCAACCGCAACAATAGAATTGACAGGCTCACAGAGTTCATTTGTATGATCTTCTTGGATGCAGATAATTCGATTCCGAGCCACATCGTAATCACCATCTGCGTATCGCTTTTTCTCATCAGGTGTCAATGGCTGGGGGGTGTCTATATTAGTTTGTCGATAAATCCGTTGATCGTTGAAGTTTGAGAAATATGTAACTCCGTCCTTCACAACAAAAGCACCACCTCCATATTCGTGGACTAGTGTTCTAGCACTGAAACCCTTTGGAGTAATATCGACAATTTCGCCATTGGCAGTTCGTCTGACAATTACATATCGACCTTTTTCTGATGGTCGTGACTCGATCCAATAAACGTCCTTGCCATCTAACGCTACTTCTTGAATATTAATCGTTTCAGCAACGATAGCGTCAGCAGTAATAAGAGACTTCCAGAATCCATAGGGGGATTCCAGGGGTTGTGGTAAATCCATACTTGTAATTACTTATAGTATTTTTAACAAAATTTGCTAGGAAGTATCTCCCCATAGCAAATGTCGGATAAAAATCTATTTGTCGTGTTATGAAATTAATGTCGTTAAACTTTTAAATTGATGGAATTTTCATCCCAGCTATGTTGTAGCACTTTGGATTCCTTAGAACAACGGCAGGTTAAAAAGACTTATGCTGCGTATAATGGACTAATGCTTGATATAGCGTAACTAGGCAGGGTGGATTGTAGAGCGGTACTAATGTGTTAACAACGACAAATAATTTGTTATTCGACAAAAGAACAAGCTCAATAAATAGTTACTAGTATTTTCAAGATTATATGAATGCTATAAAAGTGAATGTAATAGTATAAACTTCTTTACAAAACGCGATGTGCGACTTATTCCTGCATTTCTCACAAGCGCTGCGATGGCTACACCCGCCGCAGGCATCGCACTTTTCATAATCCTTACCCAGAATATGTTTCGGGCATTGTTGACAGTTTATTTTTTGATGCAGTGTGAAAAACCAAAATCTAGATTTTATAAGGCTTTGAGAATTCTGGTGAGAAATACGGCTATGTTTCGTTACAAAAGGCTGGTGTACGAATGATTGAAAAGAAAAATCCCACAATCCTCATCTGGAGAGAGATAAATCGTCACCAGTGATTAGAATGAGGGAAAGATGTTTTCTATTGAAGAGTTTATCGTTGCCGTATTTTGTTGTATTGACAACTTGCAAATTGAAATTACCTAAATCTACCCAATAAAGAGACGAGGTTTGTCTTAATTAGTATCATTTTCAGCAATACTATACCTTTGGCTTACTTATCCTCTAACTTTAGTTAGAGGATTAAGTCTTTGAGCTTATCATAATGAAATTATGTATCGAAACATGATTCAGATATCAAATACCCAATTTTTTAAGACTAGACATCTCCAGAAATGATATGAAGGCGAACAACCCTTCGCCCCCAATACGGTTCGGTTAAAGGTATTGGTTTTAAATACATCCTTTACGCAATACCTGCAAGCCCATTCCCCAGACCACACTCGATTGTGAAAAATGCTTATCCGAACCGTATTACGTTCGCCCCTACTAAGGATTTTGAGCAACGCAGAATCAATTATTCGGGATGTCTACTTAATAACTATTGGGAATTCAGAATGTTGCTCGATGAATGGGATTAGCTTTCAGTATTAAAGTTTTTCTGTCTAACTGTGAGAATTAAATTACGGGCTTAACAATAGTTTTGGTTCTACTACTTATTTAGCTCCTAATTTTAATAGATAAAACTAGGATTTAGGTATCTCTACAGATATTAAACATCTTAACTGAAGCTAATCACAAACTACTACATAAGCGATACTTGATAATGCTTAAAAAGCATAATTACCATATAAAGAGGGATAATTATGACCACTGAATCGGCGGCTAAACCAATCACGCCCAAATTTGATAACTTCCAGACTCTTGCTACTGAAAAGGGAGCTGTTCGCGCTGTAGCAGAGAAAATGTTTGACTTGCCTGCACAAATAAATCCACCTATACTTGGTTCTCGCACGCGTATTTGGAAGCAAGATCCTTCTGTAACAGAACTAAAATTGCCAAGAACTGTTTATGTTCACACCGAAGTAAACGATGGGCCTAGTGACTCCCAAATTAGAATAAAGGGTGTTGTGCCTGTTCCTGCGGATGTTAATCGAGATTTTTTACCAGACCCTGCTGCAAATGTGGAAGCTTTCGACGCGGTACATACTTATACTGTTGTGCGTCAAGTTCTTACTTTCTATCAAAGAGTATTGAAGAAAAAGTTGAATTGGCAGTGGAGTCAAGATAATGGTGAGCAAGCAATCAATGTTTATCCTCATGCAGGAGAAACGGCAAATGCCTTTTATAGCCGTGAGGAAAAAGCTTTAAAGTTTTTCTATTTCACTCCCTTTAAAGATTCAAATTTAACCTCGAAAGTTTTTACTTGTCGTTCACTAGATATTGTTGCCCACGAAACTGGACATGCAATATTAGACTCGCTAAAGCCTGAATGGATCTTATGGAATGCACCAGCACAAACAGGAGCCTTGCATGAGTCATTTGGTGATTTGACATCTATCTTTTTGATTCTGTCTCAGTTGGATTTGGTCGAGTATATTGTCGCGGAGACGAAAGCAGATTTACATCAAAAGAATATATTGGCTGAACTAGCAGAGGAATTTGGACTGGCTTTTAACTTACGTAATGGGTTGCGAAATGCAGATAATAACTTAAAACTCAGTGAGGTTACTCCTGAGGTACATGACTTGTCTCAGGTATTTACAGGAGGAGTATTCGACACTTTGGCAGATTTGTTTACATCACGCAGAGATCCCTATGTGCAAGATAGTGCCGAAGTTCTCTACCAAACTGGGAAATATTTGGGTGAAGTTGTGCTGCGTGCTATCATTGAGTCCCCAAACACTAATGCCAGCTTTGCAGATGTAGCTAATGCCATGATTAAAATTGCTCAAACAGACGGCAATCACGATTACGCTAAATTTGTACAGAAAAACTTTGAATTTCGGGAAGTTTTGGGATCAAAAGCTTTTGGGACTCACATTGATTTATCCAATTTTGGTATGTATCCTAGTCGTCGTTGCGCTTGTGGGACAATGCAGCATCCACAATATAGACCAAAGGCTGCTCACTTGAATGGCACTAACACAGATGGAATGGTCAAGACACCATAGGTGTAGGAGAGCAAAGAAGCACGGGAGAAAGAAGAAGCTCCACGAGTATCTGAGTCGAATGTCATGAACAAAAGCTGAAATCTTTACCAGGGCAGGGTGTAGGGAAGTTGTTGATTTGTAAGTATTATTTGGTTCTTAGTATTTTCCCTTACATCCCTACCCCTTACACCCTTACGCCCTTACCCCCGAAAACCAGCTATATTAAGGGTTGTGCTTTTTAAGCGTGCCATTCGCATTTGAGCCAAAGGGATAAATTCTCTTCTTCCCCTCTGCTCCTCTGCAACCCTTACACTCATTACACTACTTGCTTTTAGACTTAACTTAGTGCCATTCACTCCTCACTCCAATGGAAAAAATGACAAGCAAGTTTAATTTCCCCTCTCTTTAAGAGGATGGCAAGGAGAAGAAGCAAGTGTGAAGTATAAAGTGTATGACCGCTCTCCTGTATGAAGCATTTATTTTTATATCTTTTGTCTTTCATCCTTCTTCTTTTTCTTGCTAATCAGCCAATAAGTGAGGCTTACTCAACTATGAAAGTTAAGTTTGTTCAGTCAGGAGGATACGCAGGCTTGAGAAGGGGTTGTGAAGTGGATACAAACTTACTTCCAAGCAACGAAGGGGCTAAGTTAAAGTCTTTAGTGGAACAAAGTGGCATTCTACAAAAAGCTAAAAGTAATCACGCGCCACATGCCCGCGACTTGTTTAACTACAACATTACTGTTGAAACGGCTGAGGGCGAGAAGTGCAATGTCTCATTTGATGACTTGAGCTTACCTGAAGGTATACAACCATTGCTTAACTATCTCCAAAATTGTGCGTATCCACTTACGCCTAATGTGAATTAGGAAAAAAGGCAATCTTTGTCATAGTGGATGATTTGTATCAAAAGCAAGTAAAAAGTTTTTTAGCTTAAGTTTCTGTACGATTGCTACCAGAAAGCCTCATTTAATAAAGAGCATTGTAAATAATTTTGAGAAGTTAAATTATGAGTGAAAACACCCATAATGTTATTTTTTTTGACATAGGCGGTACTCTTGGATCTCCAAGAATTTCACCCTTTCCCTATCGCCTTGAAGGTTTAGATGTTTATCCTTATGTGCCTGATATACTACGGCAGTTGCGTGAGCGCAACAGTCGCATCGGAATCATATCGAATATCGGCGATGATAAACCCGAAAACGTAAAGAGAGTGCTGGAAAAGTGCCAAATTTATGATCTTTTCGATTCTGATCTAATTATTTATGGTGCAAAAAACTCTTCAGAAATCTTTCAGTTTACAGCACGTCAAGCAGGCCATTCTGATACTCCGAACCAGTGTCTATTTGTTGGTGAGGATAGTCATGAGCGAAGTTATGCAATACAAGCTGGTTGGCGTGTAGTTCCACATCCTTGTCTAGTTTGGGACGTGCTCAATGGTAGCCATTTAAGGTATATTCGCATAACTGTCCCAAGCGATCGCAGTGAACAGGGATGGCAGCAAGTCATTAAATCTTTACCTGTTGTACCTTTGTATGTGACTGGTGACAAAGGAAATCAGGTTTATGCGATCGCCACAAGCCAAGCGGCGATGAGACTTGATGATTTGGGATTTGCAGTAGATCGCTTGGGTAGTGAAGACGATCCCCTGACTACAGAAGTTTATTTACTACGGGACGATCTTCAAAAAAGCACTGGCTTTCTTAACCCACAAGGAAGATCAACGGAATTTTTTGCTAATGATGAATCCTCTAAAATGGTTTTGGCTTCTTCAACCGAAGGTCTTTTCGTTGCCTTACCATCAGATCGCTCAGTGGAGGACTATCATTTTGAGAACGCCCAACACGGACATAATCTGAAACTACTGCCCGATCTTAGTTTGCTCGAACCATTTGGAGAAGGTAATAATGCGAGAACTGCTGGCTTTTTAACCTCCCCTACCACTGAGCCATCCTTAAATCAGGCTGAATTAGACAAATTTAAAGCCATTACACCTGACAAAATTCGCAGCCATGTGGAAAGGTATGCAGGGATCAAACCTCTCAATGAGCAGCAGAGAATTATCAAAAGCCGACATATTCACAGTCCAGATATGCCGTTGGTTACAGAAGCATTAGCACAAGACCTAAAAAGCATTGGGGGAGATATTTTTAGTGTCAGAATGAATCCGTTTGTCCACGAAGGACGGGAGTTATACAACGTCGAGGCAGAAATTCAAGGCAGTCAATCACAGGAGATAGTTCTAGTTACTGCCCATTTAGATTCTACTGCTGCCAGTGATAGGCCTTACGATGCCAAAAATGATCCTGCCCCCGGTGCCGATGATGACGCAAGTGGAGTTGCTGCCGTCTTAGGCCTTGCTGAGGTGATCAAAGAGCTTAATTCCTTTAAACCATCAAAGAGAACAATTCGCTTTGTCCTCTTTAATGCCGAGGAGCATGGCTTAGTTGGTAGCCAAGCTTACGCCAGAACGCAAGCGGCGATCGCTGCTCCCATTGTTGGCGTGTACCAGATGGACATGATTGGTTACAACATCGAAGCTCCTCGTTCCTTTGAAGTTCACGTTGGTTATGCAAAATGCGACGACGTGCAGCGGCGATCGCTCGTTCTCGCCCAACGTCTTGAACGGCTAGTTTCTGTTCTTTCTCCCAGGCTAGAACATCCTCAAATCTATACCCAACCCGACCCTGCCGAGGGTAGGAGCGATCATGCAAGTTTCCATCAACGGGGCTACGCAGCTTGCATTACGTCTGAGGACTTTTTCGTAGGTCCCGATCTAACATCACCCGAAGCTGAACCCAACGTCAACTATCACCGAAAGGAAGATAAGTTTGTGGATTTTGACTATGCGGCTGATATTGCCCGCGTAGTTGGTGCTGCTGCATGGGTGACAGCAAATGCTTAATTTGGGATCAGCCCATAGAAGGTTATTAAAACCTAGTTTTTTCCTTGTTCTTTAACTTCCGCTTTCTCATTACAAAAAGGTTAGGTATGCACAATGGTACATTCTATTGACCGTCGTAACTTCAGCACAAATCGTGCGACTCCAAGCCGTATTGATGAACTCAGCCGAAATGCGTCATTTGTTTCTAATGAGTTGCCTGGAGACCATACTGTTAGTGTCGCTTATTTGAATTCACTCACAGGTACGCCCAACACTCTCGTTTCAAACAATGCCCCAAGTACAGATGGATCGCTGATTGATCGAGCATTAAACTTTGTTAGCCAAACCAGTGCTGCTTTCGGATTTGCTCCCAGCGAACCAGTCGAATTTGTCCCGGACCCGACCATTGAAACAACTAGTGCTGATAGTCGCGCCGTTCACTTACAACAAACTTATCGTGGTATTCCTGTCTTTCAGATGGTTCGTACCGTTCGGTTTTCTCCTAACCAGGAGATTAATGAAGTCGTCGGAAATAACGTCAATCTCCCAACTGGGATTAATATTGCGCCGCAAATTGATGTTACCCAAGCCGTAACATCTGCTGCTGCGTATATCGCTAACCCCAATGAAACTGAGGAGATGAGAGACGGTTGGGGACAGCCAATAACCCCTATCAGCGTGGACTTGTCCGATTACAACCCGCGAGTGCTAGTTACTTTTCCCATGCCGAGTCAACCGACAGTCTTGGATCAGGACTTACGCAACTGGCACAGTGCGATCGCAATTTTATAGTATTTACGTACTATGTCAAAGTGGCGTACCTAGAGGACATTGCTGAAATTAATAACAGTAATTAGCTGTGTTAAGTATTTTTCAAATCATGAGAAAATGAGTTGAGTATTCAGAAAATAAATCTTGTAGTTTATGAGATTTACAAAACTTAACTATTGCCAGTACTTGTTAAGTAGTCAGATTAATTATACTCTGACAAATTTGGCAGAGCATTTAGAGCAGATTAGTCATGATAAAATTAACCGTTATCTTAAGAATGAAAAGTTAACACCACGTTTACTTTGGGATAATGTTAAAGATATCTTACAAGTGAGTGATAGCGCATATCTAGTTTTTGATGACACAGTACTTGATAAACGATACGCCACAGAAATAGAGACCAGTAAAAGGCAGTATAGTGGCAACCAACATGGTGTAATCCAAGGTATTGGGCTAATAAATTGTATATATGTCAATCATGAAATCGGAAAGTTTTGGATAGTTGATTATCGGATTTATGACCCAGATAGAGATGGAAAAAAAAAGATAGATCATGTTACAGAGATGCTGCAAAACCTTATATATCATAAGGCTTTACCGTTCCAAGCTGTCTTAATGGATACTTGGTATGCAACAAATAAATTGATGTTATATATTGATGGATTAGGAAAATATTATTATTGTCCTCTGAAACGTAATAGACTTGTTGATGATACGGCAGGTCAAAAAAATTATCAAAGAATTGAATTGTTATCTTGGGATAGCCAGGAGTTAAAATCAGGTAAAATAATTAAAATAAAAAAGTTTCCCCAAGCTACAAAAGTGAAGCTCTTCCGGGTAACTGTCTCGACCGACAGAACGGATTTTATCGCTACTAACGATTTATCTCAAGATTCTACGGACGTTGTACAAAAAGTGTGTAAGGTTCGATGGAAGGTTGAGGAGTTTCATAGAGAATTAAAACAAGTAACTGGTATTGAATCGTGTCAATGTCGCAAGGGACGTATTCAAAGAAACCATATTGCCTGTGCTATTTTAGTCTGGCTTCGACTCAAACATTTAGCTTATCAAAGCTACCAAACAATTTATCAAATTAAACATGGATTATTATCCAATTATTTAGTTCAGCAACTAAAACGCCCGAATGTTCCCATGTTTATTGTCTAGTTGTTTGGCGCTCGGTGCGGCGCAGCCGCACCGTCGTTTGTGACAGTTGCGTAAGTCCTGTTGAAATAAAAATAATGACAAACGCAAGAATATTTAGTATCAATTATAATATCTAAATAAAAATTATTATTTCAATTTAAGTGCAACTTAGCGAACTCAGCCTATTTCAAACTTTTCGGCGTAGCCTGCAATTGGTAATTCAGTCAGCAACTACTGAGTTACGCACTCTTATATTTTTAACTTTAATTAGTGGTTCTAGCCCAGCAATTTCACTGTTTCTCAACAAAATTATTATTGACCAAATCTCCCATTTATTAGGGAAATATACAACAGTAAGCTCGCTCATTCTTATCCTACAGGAGCCAATCTTACTTGGGAGCATTGGAGGATTAATACTACTTAATTTATTAACCGAATCAATGAATGCGATCGCTAGCTTGGTTTTTTCTTCTCTGCGCGATCGCGTTCAAGGTTTCGCTCAAAGTATTGTGCTGAATAAAGTTGCCAATTTTGCGGATATCGCGTTATTTGAAACCCCCGAATTATTGAACTTGGTTCAACTGGCAGAAACAGGAATAGAACGGCTCAAGGAACTATCCTTGCTTGTAATTACAACTTTGCATGGTTTTTTTATTTTAATTCCTGCTATTTTGCTCTCTGGCTCAATTACTTGGTGGATACCGTTAATTTTATTTACCTCTGCTACACCAGCGATTTATGTGGAATTGACTTACCGCAAAAAAAGCTGGGAAGTCGAAGAAACTCAGGCGAGTCTTGTCCGCCAAATGAACTTGCATAGGGATGTCTTAGTGGGTGAAGCTTATGCCAAAGAATTACGCTTATTTCAGCTACAGCCTTTATTGCTGGATCGGTGGCAAAATCTTTTCCAGACCATGTTTAGATCGATGCAGCAAATCCGCAAAAAAGGGATGGTGCTGGTAATCACTTGGTCAATGGTGAATGGATTAGGAACCGCTTTACCCTATATTTATGTTGTTATAGGAGCTTTACGTGGGATTTATACTTTAGGAGATTTAGCACTTTATGCAGGTTTGATCCTACAAGTACGCCAGAGTTTGTTTTTACTGATTAATAATGGGTCTAACTTGTATGATGTGGTTTTGGGGACTCGTCCGATTTTACAATTATTAGAACTGAAGCCGAAATTGCGGTTATCGTTAGCCTCAAGGGAGGATACTGCGGCTAAATTGTCGTTGACACCAAGAGTGATCGCCCAGCACCAGGGAATCCAAATCAAGAACTTATCTTTTTCTTATCCAGGTAGCGACAGCAAGATTCTGGACAACATCAACCTCACAATTCAGCCGCATCAAACGATCGCCTTAGTTGGGGAAAATGGTGCGGGGAAAACAACTCTGGCTAAGTTACTCTGTCGCCTGTACGATCCAGGAAGTGGCGAGATTTTGTGGAATGGACAGGATTTACGGGAAATTGACTTGGTACAGCTATACTCACGCCTTGCTGTGGTGATGCAAGATTACGCTCGTTTTCCAGCTACAGTGTGTGAAAATGTGGGTTTTGGGTACTTATCTGCGTTACAGGATGTTAACGCCATCAAAGAGGCACTGAGGGCAGCTGGAATTGCCAAGGTAGTGGACAATCTGCCGCAAGGCTTAGAGACACTATTAGGTAAGCAATTAGCCGATGGCGTGGACTTATCAGGAGGACAGTGGCAAAGAATCGCGATCGCTCGTGCGCTGATGCGATTATCCTCAGCAGAACTATTAATTTTGGACGAACCGACAAGCGCACTAGATCCGAAAACTGAGCATGAAATTTACCAGCTTTTACGTACCATTGCTGCTAATAAAATGGCTGTTTTCATCAGTCATCGTTTAGCTTTATCCAAACTGGCAGACCAGATTATTGTTTTAGAAAATGGCAAGATTATAGAAACAGGAAGTCATGAGGAATTAATAGTAAGAGGTGGACAATATCATCTTATGTTTAGCCGTCAAGCAAGTAGCTATCAATAGACCGAACTATCAAATTAAGGTTGGGTAATTTAACTTTCAAAAAAGCTTAATTAACTTTATTCCTAAATTATTAGCTGCAACTTCAACAAAACGTCTCTTTATTTATTGCACTTTACTAAAAGTTATTGCTCACAAGGCTGTTCCTGACCGCCCGGCTAGAAATGAACCACGAGTCCGTAAACGTCGTCCCAAAATTTACCACTTGATGACGAAACCCCGGCATGAATTACGCAAGCAATTGCAAACGGCTTAAACCACAAGCGTTTCGGCTTTTCTTAGTGCCATTCGATCCAGTAGTAAATCAATCCTCCAATCCGGGCAAGGTAGCGATCATACCAGCGAGGGATGCGGCAATCAGCAGATGGTGCAGTTCATTCCAGGACTCTGCAAAATGCACCTTTAGCCAGTCAGATTTGCGCCACCAGCCCATCGTTTCATAGAGGTGTAAAACGGAGGTGAAAGCAAAATAGGGTACACGGGCAACGGTTTCCAGTACAAAAAATCGTGCAAAGACGCGATCGCGGCCCTGATAAAAGGTATTCAACAAGGTTTCCAAAAAATTAACGAGCAGTCGGATCATGATGTTTAGTGTCTTAGTTTTTTGAAGCGATGTCCTGCATGAGCTAGAGTGAATGCGTCTAGTAGTTCGCCAAGTGAACTTGGCGGGGTAAAGGGAAAGGGGGAAAGGTTTCAAATCCCTTACCCCTTACCCCTTCCCCTTTCCCCAGCCATCACGCAGCATTTTTGGGTTGGCAGACTACTAGGTCAATGTTTGGAGTTGGCAACCTGTTCAGAAAGCGTCAATAAAAAGGCGAGGTTAGTTGCTGCTTTAAGCGCGTGGCGTGCGTTGGCGGGTATAAAAGCAAAGACTCCAGATTCTAGAACAATCTCTTGATCTTCCAGCGTCAGCACGCCTTGTCCTTCAATCACATTCACAGTCGCATTGCGAGGATTGGTATGTTCTGCAATGGTCGATTCTGCCGCCAGAGATATCAGTGTATAGCGGCAGTTTCCATCTTCTAGCAGAACCTTACTTTTAGCTCCATGCTGGGGATACTCAATGATGTCCGCCCAACGAATTTTGGTTATCTTCAATGAGAGTATGCTTGTAGTCATGGGATGATTCCTTTGTTGCAGAGAGATTAATTTGAGCGACAAAGACACTTATAGATTAGACTTCTTTCAGAAGTGGGGAAGGGGGAAAGGGAAAAGGAATAAGAAAAAACCTTTACCCTTTAACCTTTACCCTTTTCCCACCTCTTGCAAAAGTTACTTTTGCAAGAGGTTCATTGAGTGTCTGTATTGAATTATGGAAAGACAATTTTGGCGATCGGCGCATGACCTAAGAAAATATGGGCAGCCGGTCTCAGGACACTTTCAGAATAGATAATCTTTTGAATGTCCAGGCTGGGCGCACGTTTGGCGGTGGCATTGTAGGTGGCGATTTCTCCTTTTAGGCTGAAATCGCTCTGAGTGAGGTAGTGGTCATTGTCGTGCATTCCCTGGAAAATAAAGTTATAGATGGGGTTAAGTCCCATCGTTGTGTCGTAATTATCGGGAGATACCCAGAGATGACTTTGCTTGATGTCAGTAAACATCTCTGCGGCATTGTTATAGCGCTCGTACCATGAGAATTCTAGATTGAGCGGGGTACTCTGAAACTCACCCCAGAGCCAATCACACAGTTCTGCGAGTGTTGCAAATTGAGTTTGTAAATCGCTTAGGTGAACATCAACGTGAGTGATGCGATCGCTGAATCGGCTCAGGCTCTCTTCCACTACACCACTAACCTAAGTTGCTAGTGCTTCGTGACCTTGGATGTTATGGCCGGTATGGATTTGGATTTGCACGATGTTCTCCTGTTGTAATTGTGATTGGCTTAGTTTCGAGCCTTCAGGTTAATCTCACTTAAAGTAATCTGCAACTATTGCAACCAAGTATCTGGCGATCGCTTCCAGCAGGCGGTTACGCCATCGCAAAAAAAGTGAGGCTATCCTACCTGAACTTCCTCCTCAGTTTGAACCTTTGCTAAAGCCGCTTTTAGATTTGCTTCCTCGACCTCCGCAAAATCCCTTATTAGTTCCCTTGTTTTTCACTAGAACATAAAACATCGAATACTTCTTGTATCTTGCTAGGTAAATAAGTTAAATTTCATCTACCACTTTTGAATGTTTTATCAGAATCTGTATAATTCATACGATTTAAGTATTGCAGTTGCAGCAGGTGGTATCAGTGGCTACGCTAAGGTTAATTCAAAAATCTCTGCTAGTGTGGCAGGGACGGCAATAGCTTAACTTCTTCCATTCTTGGACAAAAGGATCTTCCACTTGGTTTTCCACGAATTATTGATTCAGAACAGGAATAGCAGAAAAATATGAGTAAGCTCATCTTAATTACAGGCATAAGTAAAGGTCTAGGTTATGCGATGACCGAGGGTTTTATTCAACAGGGGCATACTGTTATTGGTTGCGCCCGTTCATCAGATGAAATCGATAAAATACGCCAAAAGTTTAGTGCGCCCAATGATTTCACATCTGTAGATGTAGCAAATGAACAGCTTGTAAAAAAATGGGCACTAGACGTACTTCAAAAATATGAACCGCCAGATATATTAATTAATAATGCGGCAATTACTAATTATCCAGCACCTTTGTGGGAAATACCATCTGAAGAATTTTCTGATCTTATAGATATCAATATCAAAGGAGTAGCGAATATAATTCGCCATTTCGTACCAGCAATGGTGAAAAAGAAACGGGGTATTATTGTTAACTTTAGTTCCGGCTGGGGACGTTCGACTTCAGCCCAAGTTGCACCATACTGTGCTTCCAAGTGGGCAATCGAAGGATTAACTCGTTCTTTGGCACAAGAATTGCCAACTGGTATGGCTGCTATACCCCTCAATCCAGGTATTATTCATACAGATATGCTTTCTATTAGCTTTGGAGAAGAAGCTGCTAATTATACACCCGTGTCCGATTGGGTATTGAAAGCTGTTCCGTTTATTCTCAATTTAAAACCCAAAGATAACGGGATTCCCTTGACTATACATTAAAGAGTGAATCTCAATTGCGTAGGCGTAGCCCGTCGTAGACATCGTTGCCATTAGGAGCCGACAGTTGAATCATCTCAGTAAAACGTGAATACTTAACTGCATCAGTAGGGGGATAATCTGCCGACACTGCAAGTAACCCAATTTTGATATCCTCGAAATAAATCACACCCCCAATACGTCCTTCAATTTGGAAAGCTCCATGAAATAAATGATATGGAGCTATGTAGATCAGCAAAAAGTCACTAATATTTATTGCCCTGCTAAACATCTGCTGACAAGTTTTTTGGAGGACAGCATCTAGATATTCATTATGGGCAGGTTCACCCAGGTCAGTAAATTCCGGCCAATCTGCAAAATGATCCATATAAAATAGCCAGATATCGGACAAGTCTGCGTCATTTGTCAGTTTTTGCTTAAGTGACTGCAATCGGTCGATATTCATATTGTGGCAAACAGACAGTACTGTTAAAAAGTTATCAATTATTTTTGCGTGAATGGGGGATTGTTGAGCCGGCTGGTGAATTAGCTGGTTTGCCTTTCCCTATTAATGCTCAGATGCTGCGGCATGGAACAGGTTATCCCAAGGCGAATCGAGGCGATGAAGTTTGTAGATGCTGAGTTATCATTGTCTACTCTTACACTTGTACACTTAACCGTATTTTCTCGTAATTTCTTTCAAAAATCAAATAGGATTCCTATCTTAAGAAGTTAATATAAAGCCGTCAATTTCCTATATGAAGGTTAGTTAAATGTTTGCTCAACTGTCTTAACTGTCTACCTTATTATCTTCTTAACTGTCTTAACTGTCTTAACTGTCTTAACTGTCCACCTTATTATCTACTTAACTGTCTTAACTGCTATTGCATTTTATTGACAAAACTGAGATTATTTAAAAGATTTAGGTTAAACAGACTAATTTCATAAAATTTGTACTTTAATACAACAATAATTTATAGATATTATCTATAGTAAATTGATATAACAAAAAAAAGGCTGTTCCTAAATTAATTGATATAAAATAAAAGCAAAATTTATATTTTGCAATATGAAACAGAGTAGTGTTTACAATAGCTTTTCGGTTGCCTAAATTATAGATTAGTAAGTATAAACTTGTAATTTTTAAGTATATTTAAATTATAGTAAAGAGTGTAAAAAATGAATTTTTTAGAAGAAGATAGTTTATTTTTGAAGAAAATACAACAACTAAAAACTAAACTTGAATTAGTTTTATTGGAGAAAGCTCCATTAAAGGAATGCACAGTGATTGTGAATAAAACATATCCACTGGAAGTTGTAACATATATTGTTTCAAGCTCAAATAACTCGCTAAAGCAAATTTGCTCTTATCTTCAAAATGTGTCCGGGGAAGCATTATTACCCAAAGCCATAGTACCAGTATCATATATACCTTTAACTGCCACAGGAGAGGTAGACGAATTGGCTCTGATGAACATTCCTATTGTTGATGAAAGTTTAATTGAGCAAGTAGAAAAGCAATTAAACTCGCATCACAAAATTGAACAGGCAGTGGTAGTGGTGCAGGAGTTGAGAAAGAATATCCCCTCACTCCATTTATCGGATTTGATCCCAGATTGGCAAGACAAGAATGCGATCGCCGGAGGCGGGGTTTTGCCCATCGCTAACGTTGTCCCAATTCCCATAGGCTCCCAAGCCAATACACAACAACATTTCTCAGAGCCAAAGCCACTTGCCATCAGCCACGGCGGTATTCTACCGGATGATCCCAATGCACCTATTACCTTGCCCGAAGTTTTGCAAACAGCCGCGCAACAGGTTAAAAGTGCGGGAATTATTTACCTGTTGCCCGATGGCACAGAACTACGCCAATCATACGCTGAGTTACTGGAAGTTGCAGAGCGGATTCTTGCTGGTTTGAGAAAGTTGGGACTTAAGCCAAAAAACAAAGTCATATTGCAGATGGAACTTAGCCGTGACATTATTCCCGCTTTTTGGGGCTGTATATTGGGAGGCTTTGTCCCCGTAATCATGGAAGTGCCACCGACTTATAGAGAATCAAACAAGGTGGTGGATAAGCTTTGTCATATTTGGCAGTTCTTAGATAGTCCAGTTATCTTAACTACAGAAGCTCTCAAACCAGAGATAGAATTTCTATCAGAATGGCTACCAGTAGAACGCATCAAGATAGGCACAATTGAAGTATTAAAAAACAATACTGCCAGTAAACAATATCACCATAGTCAACCAGATGAGGTAGCTCTTTTCAACCTGACTTCTGGCAGTACAGGAATACCAAAATGCGTTCAATTGACTCATCAAAATCTCATTGCTCGCGCCAAAGGGGCTAACCTACTTAATCAACACGAGTCAGAAGATGTAATTTTGAATTGGCTGCCGTTCGATCACATTGGCAGCATTTCCGACTGGCATATTCGTGGTGTGGAATTGGGTTGCACGCTGGTTTATGCACAGAAAGAATATATTTTGGGTCGCATTCTCAACTGGTTGGATTTAATTAATAAATACCAGGTTACTCATAGCTGGGCACCCAACTTTGCTTATGCGATAGTTAATGACTCTCTCAAACAAGAACCAGAACAAAACTGGAACTTATCGTTCGTGAAATTTCTACTGACAGCTGGTGAAGCAGTATCTAGTAAAGCTGTGGAGGATTTTCGAGAAAACTTGGTTGTATATGGACTCAAAGCAACGGCAATTCGCCCAGCCTTTGGTATGGCTGAGATGGGTTCGGGAATTACATATTATCAGCCCCTTCAGGAAGCACCTTTGTTGTTCCATAGAGTAGACAAATCTATATTGCAAGGTACTATTAAACGAGTAGAAACAGACCATCCAAATTACAGTACTTTTACCGATTTAGGCTCAGTCATTCCTGGAATTACCATTCGCATAGTAGACGAGCAAAACTCTGTATTAAGAGAAGACACCATAGGGCGTTTGCAAGTTAAAGGCGATGCAGTTTCTCCAGGATATTACAACAACCACAATGCCAACAATCAATCTTTTTTAAAAGATGGCTGGTTTGATACTGGAGATTTAGGATTTATTACCAACGGACAATTGGTGGTTACTGGTCGTGCCAAAGAAACTATTATCATCAATGGAGCCAACTACTACAGCCATGAAATTGAAGCAGTAGTTGAAGAAATTGCAGAAATTGAAGTGTCCTACACTGCCGCTTGTGCAGTATGCAATGCTGATGATGCAACAGAGAAACTGGCTATTTTCTTCAGTTCGCCGATTACAGAAGAAGCAAAACTGCTAGAGCTACTAAAGAAAATTCGCCAAACAGTGGTGAACAAAATCGGCTTAAATCCTGATTATTTAATTTTATTAGCTAAAGAAGATATCCCCAAAACCGTTATTGGTAAAATTCAGCGATCGCAACTTAGCGATCGCTTCCATGCAGGTGAGTTTAACCCGATTCTAAAACGATTAGATATTTTACTAGGCAATACCAACACTATTCCTGATTGGTTTTACCAAAAAGTCTGGCGACCCAAGCAAGCCAAGGCTTTGAAGACTTTATCCTCAAATTTTATAACTATAGTCTTCCTTGACGAGTTAGGGTTGGGGACATTTATTTGTCAGCAACTAGAACAGCAAAACCTACCATGTTTGTGTGTCTCACCTGGTTCATATTTTGCTAAAAAAAGCCCCAATCACTTCTTTTTAGCTCCTGGAAATGCAGATCATTATCAGCTATTGCTTGATACCATAAAAGCAGATAACCTGACAATTGGTCAAATTCTCCATTTGTGGAATTATCAAGAGTATCAAGGAGAAATAAAAAGCATAGAAGCTCTTGAAAAAGCCCAAAGTCAGGGAATTTACAGTTTATTGTTTCTTACTCAAGCCCTAGCAAAAACTCAGAATTTCCAAGATTTAGTTCAGTTATTGTTTGTTTCTAGCTACACCCAGTCTACGCAACCAACAGACAAGATAGCTTATGAAAAATCTCCTGTTCTCGGTGTAATTAAAACTATCCCCCAGGAAATACCCTGGTTAAATTGTCGTCACATCGATTTGACACCAAATTTGATACAGGTGAATGCGAACTATCTTCTACAAGAACTCCAGGTTTTATCAAAAGAGCAAGAGGTAGCTTATCGAAATGGGCAGCGTTTGATTGCAGGTTTAGAAAAAGTTTATCTGGAAGATAAACCAAAGCAAAAACTTCCCTTTAAATCAGGGGGGATGTATCTAATCAGTGGTGGGCTTGGGGGTGTTGTAGTTGAAATTGCTAAATATCTAATTAAGTTTTTTAATGCCAAATTATTATTAGTAGGTCGGACTCATTTACCAAATGAAAATATCACATCCAACGTCTCTACGGAAATATTAGAAAAAGTAAAGCTTTACCAGGAATTAAAGCAGTTGGGATCGGTGGTTTATGAGGCAGTGGATATCTGCGACTTGCAAGCATTGCAACAAGTGGTAGAAAAAGTCAAGGCTAACTGGGGAAGTCAGCTGGATGGGGTGATTCATCTGGCGGGAACTTACCAGGAACAAATGCTAGTGGATGAAACACCACAAAGTTTAGCTGCAATCTTACGACCCAAAGTCTTAGGTGCTTGGGTACTGCATCAAGTTTTAGAGAAGCAAGGACAGGGGGTTTTCATTAGCTTTTCGTCTTTAGCAAGTTTCTTTGGTGGCGCTACCATTTCCGCTTATGCTGCTGCTAACAATTTTTTGGAAAGCTTTAATCAATACCAACGTTCTATTGGTGGGTTGCACAACTATTGCTTTGCTTGGACAATTTGGCATGATACAGGGATCAACAAGGGTTATCAGAGGCAAGAAATCACCCACGCTCAAGGCTTTTATGAGATGAGCCTGCAACAAGGGTTGTATTCCTTCTTGGCTGGTTTATATCATGACCAACCACAGCTGATAGTCGGTTTAGATGGCAGTAATGCCAAAATTCGGCGTTTTACCTCGGAGTTTCCAGGGTTACAGAAATTAACTGCCTATTTCACTACGAGTAACGGTTCTGCCGTACCAGAGCTATCAGATTTTACAGTGCGCGATCGCTTCACAACAACTGTCAACTGTGACTTCGTGCAACTATCACAAATGCCCCTCACTGCTAGCGGCGAAATTAATCGAGAATTATTGGCTAGGGGTATGACTAGTATAGGAGCGATCGCTCCCCGAAACGAAACGGAACGGCAAATAGCTCAAACCTGGCAAGAAGTTTTAGGAATACCCCAAATCGGCATTCACGACAACTTCTTTGAACTGGGAGGAAATTCTTTGCTAGCCTTCCAAGTCATTTCTCGGTTGCGTGAGACTTTTTCTGTTGAATTGTCGCCCAATCGTTTTTTTGCATCGCCTACCGTAGCTGGTTTGGGAGAAAGTCTGGAGGCGCTACAAACTGTTGTCACCAAATGGAATGCAGCTATGGATGACGCAGAAAAAGAATATGAGGGAGGCGTACTATAAATGACAATAATAGAATTTGTATCTTATTTAAATAGTTTAGGCATAAAAATTTGGCTGGAAGGCGGCCAGTTAAATTATCGCGCTCCCAAGGGAGTGATGAACCCAGACCTGAAAAATAAATTGCTAGGGCGCAAATCAGAAATCCTGGCTTTTCTAGAAGAAGCTCAGATTGCAACAGACTCTTCCTTTGAGCCAATACCATCTATAGAACGCTCTGAAGAGTTGCCTTTATCTTTTGCCCAGCAGAGGATGTGGTTTCTCTATCAATTAGAAAGCCAAAGCCCATTTTATAACGAGGGTTTACAGCTGCGCGTTGCAGGTGTACTCAACGTAGAAGCTCTACAGCAAAGTATCAACGAAATCATCTGCCGTCACGAAATTTTACGGACAACATTTCCCGCAGTTGACGGGAAACCCTTGCAAATCATTTCTCCTAGCTTGACAATCAACATACCAGTGCTGGACTTGCAAGGTTTAGAAGAATCAGAAGTACAACAGATTGTCACCAAAGAAGCTCGCCAGCCTTTTGATTTGAGTAATGGCCCTTTATTGCGGGTTACTTTACTGCGCCTGGGATCGGAGTCCCATGTCCTGGTATTGATCATGCACCACATAATCACGGATGGCTGGTCAATGGGGATATTCATCCAAGAATTGTCCACTCTCTACCGAGGTTTTACTCTTAATTCCCCTTTGCTTCTGGCTGAATTGCCCATCCAGTATGCTGATTTTGCAGTTTGGCAACGACAGTGGTTGACTGAGGAAATTCAAAAACAGCAACTAAATTACTGGAAGCAACAGTTAGCCGATGCGCCACCCTTATTAGAACTACCCACAGACAAACCACGCCCCGCCGTTCAGACTTTCTGTGGTGCTACCCAGGAATTTCAAATTGACCAGAATTTGAGCAAGCAAATCAAAACCTTCAGCCAACAGTCAGGAGCTACCCTATTTCATACCCTACTGGCGGCTTTCGTCGTTTTAATGTTTCGTTACAGTGGTCAAGATGATATCTGCATTGGTAGCCCCATTGCCAATCGCAACCGCAGAGAAATAGAATCATTGATTGGCTTTTTTGTCAATACATTGGTACTGCGTAACCAGATCAAAGGAAATCCCAGTTTCAATGAGTTTCTCTCTCAAGTGCGGCAAGTTGCAACTTCCGCTTACACTCACCAAGATGTTCCTTTTGAACAAGTGGTAGAAGCGTTGCAACCAGAACGTTCTCTCAGCTACAATCCCCTATTCCAAGTGGTCTTTGTCTTAGAGAATTTCTTGTTGGATACATTAGAATTGCCTGATGTCACCCTGACTCCTCAATTTGTAGAACGTGGAACATCTCAGTTTGATTTGACCTTGGCCGTTTGGGAGACAAAAGCAGGACTGATAGGTTCGTGGGAATATAACAGCGACCTATTTGAGCCAGATACCATTGCGAGGATGACAAGTCATTTCCAGACTTTGTTAGCAGCGATTATTGCTAATCCAAATCAATCCATTGGTGAATTACCACTGCTGAGTCAGCAAGAGCGACATCAGTTGTTAGTGGAATGGAATGATACTTATACGCCTTATCCTAAGAGCAAATGCATCCATGAGTTGTTTGAGGAACAGGTAGAAAAAACACCAAATGCGATCGCAGTAGTCTATGAGAATGAGTCCCTCACATACCAACAGTTGAACGATCGCGCGAATCAGTTGGCGCATTATTTGCAAACTTTAGGTGTGGGTGCAGAAATCTTAGTAGGAATTTGCATTGAGCGTTCGTCGAAGACGTTGCCGAAGGCATCGCTCTTAATGGTAGTAGGATTGCTGGGCATTCTCAAGGCTGGTGGAGCATACCTACCCCTTGACCCAGCATATCCCCAAGAGCGGTTGGCGTTCATGCTAGAAGATGCTCAGGTATCGGTGCTACTGACCCTGGAAAGTCTGGTTACAACCTTGCCGCCACATCAAGCGCAGGTAGTTTGTCTTGATAGCGTAACCTTCAGCGCAAGAACAGAAAATTTACTCCACACAGTCACAACTGACAATCTAGCTTATGTGATTTATACCTCTGGTTCTACCGGCAGACCCAAAGGAGTGCAAATTGAACATCGAGGATTATTAAATCTCGTCTTTTGGCATCAACAAGCTTTTGCCGTGTCGTCCCTTGACCGAGTAACACAAGTTGCTGGAGTAGCATTTGACGCTTGTGGTTGGGAAATCTGGCCTTATCTGACGGCGGGAGCTAGTATTCACTTTCCCGATGATGAAACCCGGCTTTACCCTGAGCAAATGCGAGACTGGCTGTTGTCAAAGGCAATAACCATTAGCTTTCTACCAACACCAATGGCCGAGAAAGTTCTGTCATTAAATTGGCCGGCCAATGCTGCTTTGCGAACTTTGCTCACGGGTGGAGATCAACTTCATCAATATCCTTCGACTTCTCATCCCTTTGAGGTGGTGAATAATTACGGGCCAACGGAGAATACTGTAGTCGCAACATCCGGTACTGTTCCGAAAAGACAACAAGCTTACTTACCACCTGCGATCGGGCGAGCGATCGCAAACACCCAAGTTTATGTACTGGATTCCCTGTTGCAGCCTGTACCCATTGGTGTCATAGGCGAATTGCACATCGGCGGTGAGAGTTTGGCACGGGGTTATCTCCACCGTCCCGACCTAACCGCAGAACGCTTCATTCGTAACCCTTTTAATAGAAGCAGGGGGCATACTTCGACTGCGCTCAGTAACCAGGGAGTAGGGGGCAAGGGGGAAACAGAAAACTGCGATCGCTTGTATAAGACGGGCGATTTGGTTCGCTACCAAGCTGATGGCAATATAGAATTCTTGGGTCGCATTGATCACCAAGTCAAGATTCGCGGCTTCCGCATTGAACTTTCGGAAATTGAAGCTATTTTGACTCAACACCCCCAGGTACGGGATGCTGTTGCGATCGCTAGAGAAGATATACCTGGTGTTAAAAGTTTGGCGGCTTATATCATCCCAGAATTGACACAGCCAACCAGTAATGAGCTACGCCTGTTTCTCAAGTCAAAGCTCCCCAGTTACATGGTTCCTGCATCCTTCACAATTCTAGAAGTTCTGCCGATTACCCCCAACGGGAAAGTAGATCGTCGGGCATTACCAGTACCGGAGTTCGAGTCCGATGAATCCACTGGCTTTGTCTCTCCTCACACCCAGACTCAAGAAGTCTTGGCAAAGATTTGGCGGGATATTTTAGTCCTAAAACAAGTCGGCATCCACGACAACTTCTTTGAATTGGGTGGGGATTCGATCATTAGTATGCAAATTATTGCTAAAGCTAATCAAGCTGGACTCAAACTTACTCCAAAACAACTATTTCAACACCAAACAATTGCTGAATTAGCTCCTGTTGCTGGTATAATTAGCTCGGTTCAATCAGAACAAGGTTTAGTTACAGGGATTGTCCCTCTAACACCGATTCTGCACTGGTTCTTTGAGCAAAATCTGCCGGAACCTCATCACTTTAACCAATCCTTCCTGCTAGAAGTTCCCGCAAATTTGCAACCGGAATTACTAGAACAGGCATTACAAAAGTTACTCTCCCATCACGATGCTTTACGACTGCGGTTTGTGCAGCAGGAGGGGCAATGGCAGCAGTACAACAGTGATGCCAGCGATGAAGTATCGTTGGGCATTACAGATTTGTCATATCTGCCCCCAGCAGAATGGTTAAAGGCGATTGAAGCAAAAGCGGACGAAACACAAAGCACGCTGAACTTAGCAGATGGGCCGCTGATGCGGGTCGTTCTGTTTCACTTAGGCAATTCTCCCGCACGTTTACTCATCGTCATCCATCACTTGGCTGTCGATGGCATCTCGTGGCGGATTTTGCTAGAAGACTTATCTGAGGCATACAAACAATTAGAAGTTGGCAAAACTATCCAACTACCTACAAAAACCACATCCTTTAAGGATTGGGCAATTCGATTGCAGGATTATGCCCGCAGTCAAGAACTCCATTCACAGCTAAATTATTGGCTGGACTCAATGCGGTTCCCAATTGCTCCTTTACCGTTGGATTATGCTGCTATTGCTCAAGATAACACTGTAGCTTCTAGTCGGATTGTATCTGTATACCTGAGTGTAGAACAGACTCGCGCCCTGTTGCACGATGTCCCCGGAGCCTACAACACCCAAATTAACGATGTCCTGCTGACGGCATTGGTGCAAACTTTCACTCGTTGGACAAGTTCTTACTCCCTACTGATTGACTTAGAAGGTCACGGACGAGAGGACTTGTTTGAGGATGTGGACTTGTCCCGCACGGTAGGCTGGTTTACTAGTATATTCCCCGTTCTCTTAAAACTTGAGGATCGCAACGATCCCGGAAAGGTTCTCAAGTCGGTAAAAGAGCAACTGCGACGTATTCCCAACCGGGGTATTGGTTATGGCATCTGGCGATATCTTAGCCTGGATGAGAGCGATCGCAATCAATTACAAGTGTTCCCCAAAGCTGAGGTGAGCTTTAACTACTTAGGTCAATTCGATCAAACGCAGTTAGCAACCCTTGGCTGGAAATATGCCCAAGAGTCTAGCGGTTCCATTCACAGCCCCAAAGGACAGCGCCGCCATTTGTTAACTGTGAATGGATTAGTTGTTGAAGGGAGGTTGAAATTAGAGTGGCAATATAGCGAGCATTTTCATTCCTGGGCCACTGTAGAAAATCTCGCTAATGAGTATATAGAAACCTTAGAAACTATTATTGCCCACTGCTTAACTCCAGAGGCAGGTGGTTATACTCCTTCTGATTTCCCAGAAGTTGAGTTTAGCCAAGAAGCTTTGGACGAACTGCTAGCAGAAATTAATTAAATAAAGTCGTTCACATCTAGAAAGTAGATTTCTGTTTTAACAAGGTTTTCTGCAAATAAACTAAATTCCTGGAGGTTATCTATAACCAAATTGCCAATGACTCGCTACCAAAAAATATCATGATGATTACTCAGGAAAAACTATGCTGGAATTTCAGATTGAATTTCAACCTCGTATCCCTCCTTCAAAAAATTTAGTCATAGGTACTTTGGGGCCTAATGCTACTAGTAGCGACTACGCTGCCAAGCATATAACTAACCATCTGCTCTCAGAACAATTTACTGTATCAACTCAGTTATTTGATACTTTTATAGATGTCAAAGAAGCTTTACTACAAGACAAAGTAGATATGGCTTTAGTGCCTCATGCTTACGACCGAATTAATGAGTTTTACATGGAGCCAAGTTTTGATTTAGGCTTCATTTTTATATTTCCTACTCCAGTTTATGGATTGGCTAAGAAAAAAAATAAAGAGGTAGTTTTCAATGGTTCTAGAATTGTTACCCATCCGGCTCCTCTACCTCTGTTAACAAAACTCTTGCCAGACTCTCAAGATCAAACACAAATACAAGTGGATTTGTCTCCTTCTACCAGCGATTCAGCGATGCAGGTAATGCAGGGTTTAGCCGATTTTGCTATCACTAATGAGAATGCGGTGAAAGCCTACGATTTAGAATTTATTTCAATCTATGGAAACATCCGTATGAGTTGGTCGATTTTTCAGAAAAAATTAAATTAGCAAAAAGTTATGTCTAAATATTTTCCTCAGCCAAAAACCATCAAAATTAATTCTGATGTAGAGTTAATCGCATTTCAATGTCAAGACACAGTTGTGCAATTAGCTTCTATTCCCCCAGGAGCTACTTTTGAATTACATCGACATCCCGAAAGTCAAATTGGAATGCAAATTGCGGGACGTTTGGAATTTAACCTCAACGGGACAAAAGAAATTCTCGAACCCTTTGGGCAAGTTTATGTAGCTGGTTCTAATGTTCTTCATGGTTCTAAAAACCCTTTTTCAGAAACAGCATTAGCGTTTGATGTGAAACGCATCACAAATTCTGAGGAAGCTGAGGAGGCTATTCTGAAAGTTTCACCAACTCAAGATGAAATTACAGGTTTTGAGTGTCAGTCTGTTGCTGGTTCTTGGTTTGAGATTGTCATCACCAAAATTCCTCCAAAAGGAATAATCCCAATTCGCCAATTTGGTAATGAAACAATGGGAATAGTTCTTAACGCTCGATTGACGATCGCAGTAGAAGAACAACAGCAGAATTTAAAATATGGTAGTGTTTATTATGCTCCTGCTAACGCTCTTTATGGAGGACATAATCCTTCTGATGAAACAGTATCTGTGATTGAAGTTTTGATTAAACCTCGCTCTAATTTCTCTTTTAAAGATGCTTTTTTAAAGACAGATGTAGTGCGATCGCTAACTACTTCATAAAGGATATTTATTATGGATTTAGGATTAACACAGAAAGTAGCTTTAGTGACAGGAGCAAGTGCTGGCATAGGTTATAGCGTTGCCCAAAAGCTGGCGGCAGAAGGTTGTCAGTTAATAATTTGTGGGAGAAATTCTGAGCGATTAGAACAAGCTTATCAAGGTTTGGTTAGTTCTCAAACAAAGGTTATTCCCATTTGTGCTGATGTTCAAAATGCAAGTGATTCTCAAAAATTAGTCCAAGAAGCTCTCAGCCAATTTGGAAAAATTGATATCTTGGTCAATAATTCTGAGGGGGCGACATTTTCTAATGAAGCTGTAGAAAATCTATCTGATGAAGATTGGTTGTCTGTCTTTGAAGGTAAGTTAATGGGCTATATTCGCATGACGAATTTGGTGCTACCGACGATGAAAAATCAGCAATGGGGACGCATTATTAATATTGTTGGGACATCAGGTAAAGAACCTTCTAGTCGTCTTGTTAAATCGGGTGTGGCAAATGCTGGATTAATCAATTTTACTAAAACTGTTGCTACGCAAGTTGCTAAGTGGAATGTTTTAGTTACCTGTGTTAATCCTGGTTTGATTGATACTCCAAGGCATAGAGAATATTTAGAAGTATTCGCCCAAGAGGAAGGTCGGACTGTTGATTCCATCATCGAAGGAACGAATAAGATGATTCCTCTTGGTCGTCGCGGTGTTTCTAGTGAGGTTGCTAATTTGGTTGCTTTTCTAGCGTCAGAATGTGCTAGTTATATTACGGGTGTTACTATTCCAGTTGATGGCGGATTGTCAACTTCTGCTTTTTAACAATTACTTTTTTAAACGAACCGCAGAGGCGCAGAGGCCACAGAGAGAAGAAAGAGAGATAAATCACGTAATTAATATTATTTTTAAAAAACAATGGTAGTTGCACAAAAACAAAGTAAAAATAAAGATATTGAATCTATTTATCCTCTTTCACCTACGCAGGAGGGTATGCTATTTCATACTCTCTATGAGCCGGAATCGACAATCTATTTTGAGCAGTTTAAATTAACTATTCATGGCAATTTAGATCCAAATATATTTGAACGATCTTGGCAACTTTTGGTAGAGCGACATTCGGCTTTGCGAACTCTTTTTATTTGGAAGAATCGTAAACAATCTGTTCAGGTGGTGCGTAAAGAAGTGAATTTGCCTTGGTCTAATTTAGACTGGCGGATGTTTCCTCAGCAGGAGCAAGAAATACGTCTCAATTCTTTCTTAGATTCAGATAGAAAACAAGGTTTTGAACTTGACAAAGCTCCATTAATGCGCTTTGCTTTAATTCGGGTGGCCGATGAAACTTATGAGTTTGTCTGGAGTTTTCATCACTTGCTGGTTGATGGCTGGAGTTGGCCGATTATTTTCAAAGAATTGTTTGCTTTATATGAATCAATTCAGAATGGGCAACAGTTATATTTAGCTCCAAGTCGCCCTTTTCGAGATTACATTAATTGGTTGCAACAGCAAGATTTGGCTGGGGCAAAGGCGTTCTGGCAACAAAATCTTGAGGGTTTTACTGCACCTACACCTTTGATAGTTGAGCGAACAATCGGACAGAGTTCTCACCAACAGCAAAATATTGATGTGCGATCGCAACATCTATCAGCCGAGACGACAACTACTTTAAAATCTTTTGCCCAACAACATCATTTAACGCTTGCTACCTTGGTACAAGCAGCTTGGGGGCTGTTACTAAGTCGCTACAGTGGTGAATCTGACGTGGTTTTTGGAACTACTGTATCTGGTCGCCCTGCTAGTTTATCTGGTGTGGAATCGATGGTGGGGTTGTTCATTAATACTCTGCCGGCACGAGTAAAAATTTCTGACACAACTGATTTGTTAAGCTGGCTGGGGTTGTTGCAACAAGAGTACATAGAACGGGAGCAGTATTCATACACTCCACTGGTAGATATTCAAGGCGTGAGTGAAGTTCCTCGAAATCAACTTTTGTTTGAAAGCCTCGTTGTATTTGAAAATTATCCTGTAAATGTAACGTTGCAGCAACTCCCTGGAAACTTGAACATCGGGGAGCTACAAGACAGGGGACAGACTAATTATCCTCTCACACTGCTGGCAATTCCTGGCGATGAAATGACGGTGAAAATTTACTACGATCGCGATCGCTTTGATGCAGACATTATCGATCACATGGCTGGTCATTTCCTCACTCTGTTGGAAGGAATTACCATCAATCCTCATCGCACCCCAGGCGAGTTACCGCTATTAACAAAAGCAGAACAAGATTTACTTTTAGTCGAGTGGAATGCTACCTCACCAGCGCATCCCATCAATCGTTGCATCCATCAATTATTTGAGGAGCAAGTCAAAAAAACACCCCAAGCTTTGGCGGTGGTATATGAAAACCAACAATTGACTTATGAGGAGTTAAATCAGCAAGCCAATAAAATTGCCCACTACTTGCAACGCTTCGGCGTGAAACCAGATGTTCCAGTGGGTATTTGTGTGGAACGATCGCTAGCAGCTGCGATCGCTATCTTAGGAACTCTTAAGGCTGGGGGAGTTTGCGTTCCCCTCGATCCTACCTATCCCCCAGAGCGTTTAGCGTTTATGCTCAACGATTCTCAAACACCAGTCGTCTTAACTCAAACACGTTGGAAGTCATTACTTGATGGCAACTTGGCTCATCGTCTAATTGTGTTAGATGAAGATGGGGACGAAATCGCCAAAGAATCTGAGAGTAATCTGCAAGTTGAAGTAGCAGGTGATAATTTAGCCTATATCATATATACCTCTGGCTCTACCGGCACTCCTAAAGGCACTCTTGTTACCCAGCGATCGCTCACCAATTTAGTAGAACACCATCAGGCAAAAATGGCTACAGGTATTGGTGTGCTTCAGTTTGCCTCCCTTAGTTTTGATGTCAGCTATCACGAAATATCCGTGGCGTGGGGCTTCGGAGGGACGCTGTATATCATTCCTGAATGCGATCGCAAAGATTTAGATAAATTAATCCACTTGCTTGCTAACAACCCCGTTGGTAAAGTTTTTCTGCCAGTTAGCCTTTGGCAGCAATTAGCGGAAATATACGGAGAGCAAGAACATTTATTTCAGAATATTAGGGAAGCGATCGCTTGTGGCGAACAACTCCAAATTACTCAGCCGATGATTAAGCTGTTTAAGCGTCTGGAAAATTGTACACTCTACAATTTTTATGGCCCCACGGAAGCAGACTTAGTTACAGCTTATACTTTTAGCCAAAAGCCAGATGAATGGCCGATTTATCCACCCATTGGTAAAGCTGCTGTCAACGTGCAAGTTTATCTGTTAGACAGTAATCTCCAACCTGTGCCAATTGGCGTTCCTGGGGAACTCTACGTGAGTGGTGATGGTTTGGCTCGTGGCTACCTCAACCGTGCAGATTTGACTAATCAAAAATTTCTACCCAATCCCTTTGGAAGAGGCAGGGGGGCAGGGGGGCAGGGGAGCAGAGGAGCAGAAATTCTCGCCAGTCCCCAGTCCCCAATCCCCAATCCCCAGTCCCCAGTCCCCAATCCCCGCCTCTATAAAACTGGCGACTTAGCCCAATATCTACCCGATGGGAATATCGAGTTTTTGGGACGGATAGATGATTTAGTAAAAATTCGGGGCTTTCGCGTTGAACTGGGAGAAGTTGAAGCTGTTTTGAGCAAGCATCCCCAGATTAACCAAGCAGTAGCCAAAGTGCATGGGGAAAGTGCCAGGGAAAAATATTTAGTCGCTTACTTTGTCCCCATTGTGGGAGAGACAATCACAGTCGAACAACTGCGGGCTTTTTTGACTGAGCAACTGCCAGATTATATGATTCCATCAGCTTTTGTCGAAATGGAATCTTTCCCGCTAACCCCTAATGGTAAGGTAAACCGTCGCGCTCTCCCAGAACCAACAACCAGCCGACCGGAATTAGGTCAAACTTTTGTTGAACCGCGTACTCCCACCGAAGAAATCTTGGCTGGGATTTGGAGAGATGTTTTAGGGTTAGAACAAGTTGGCATTTACGATAACTTCTTTGATTTGGGGGGACATTCTTTACTAGCAACTCAGGTTATTGCTTTAACGCGCAAAGCATTTGGGATAGAATTACCCCTTTTGAGTTTATTTGAGTCTCCAGCGATCGCACCTTTAGCCCAAAAAATCGCCACAGCTAAAGCGCCAGACAGGCAGGAGTTATCTTTAAAACGATTCCCCCCCCAAAACGAACTAATACCAATTTCTTTAACCCAGCTAGAGTTGTGGTTTTTTGACCAATTTTATCCAGGCAATTCCATCTATAATTTACCTTTGGTCTATCGCATCACAGGTGCGCTCAATGAGAAAGCATTAGAGGAGAGTTTAAGAGAAATTGTCCGGCGACATGAGACATTGCGATCGACTTTTCAGGTTAAAAATGGCCAAGTTGTTTATGCTGTTGTTAACGATCCTGTCTTTGACTTTTCAGTAATCGATCTTCAGCACCTCCCCGAAACTGAGCGCGAAGCTCAAGCCACACAACAAGCTGAACAGGAAATTAAGCATCCTTTCGATTTGGCACGGGGCCCTTTATTACGCAGCAAACTTTGGCGTTTGGATGAACAAGAGTATCTATTCGTTGCCGTCACCCACCATATTGTTGCTGATGGTTGGTCTTTTAGTGTCCTAACTCAAGAACTGGCAAAAGTTTACGAAGCCTTCTGTGAGGGTAAGTCGTCACCTCTGACTGAGTTACCGATCAAATATACCGACTTTGCTCAATGGCAGAGGCAGTGGTTACAAGGACAAGTCTTAGAGTCTCAGCTTCAGTTTTGGAAAAAGCATTTAGGCACTAATCCGCCAATATTGAAGCTACCAACTGATCATCTCCGTCCACCAGCGCGAACCTTTAAAAGCGCAGGCCAACCGATAATTCTCTCCCAGAAATTAACCGATGCGCTGAAGGTACTGAGTCAACAGGAAGGCGTAACCCTATTTATGACCTTGTTGGCAGCATTCCAAACATTACTCTTCTCTTATACAAGACAGGAAGAGATCGTTGTCAGTAGCGCCCTTGCCAATCGCACCAGAGTGGAAACTGAAGGACTGATTGGTTTCTTTGTCAATTTACTGCCATTTTGTACCAACTTAGGAGGAAACCCCAGCTTTCGGGAACTACTTAGCCGAGTGCGTGAGGTAGCTTTGGGTGTGTACGCTCATCAAGAAATGCCCCTAATTAAGCTAATAGAAGAACTCCAGCCAGCCAGAGACCCCAGTTACACATTAATCAATCAAGTAATGTTTGTCTTTCAAAATACTCCAGAGGATAATTTACAATTTGCAAATCTCACTTTGAAGGAGCAGTTTATTGCTAGAGATACAAAAGATACCGCAGAGTTTGATTTAGAGTTAACGCTCGAAGAAACATCAACAGGTATTGATGGTTTGCTCGTATACAGAACCGATTTATTTGAAGCTGCCACTATTACCAAGATGGTTGATAATTTCCAGACTTTGCTGGACAAAATAACGAGCAATTATAACCAACGTTTAACTGAACTTATCTTAATATCTGAACATCCAAGTTTGCCCACCCCAACTATTGGATCTCCAATATCGAAGGATTTTGTTACACCTCAAAATTCTATCGAAGAAGTTGTGTTAGCTATCTGGAAGGAAATTTTGGGGATAGAGCAGATTAGCACTCAAGACAACTTTTTTGAACTGGGAGGACATTCTGCTCAAACTCTTGAAGTTATATGCAAACTACAGTCAGCTTTGCAAGTAAAACTTCCCTTGTTCAACCTATTTGAGAAACCTACTATAGTTCAGTTAGCAGAATCTATCCAATCTCAATTAAACAGTCAAAACGCTTTTTAGACTAGTAGTTTAATAAAATTATAGAGGTGAAGTCGTGGTAGAAAAACAGCGTGGCGTAACAATATGGTTAACTGGTTTGAGTGGTGCTGGCAAAACCACTATCTGCCGATATTTAGATACAAAATTGCGATCGCAGGAATATAAAATTGAAGTACTTGATGGCGATGTAGTACGCCAAAATTTAAGTAAGGGGCTAACTTTCAGCAAGGAGGATCGAACCGAAAATATTCGGAGAATTGGTTTTGTAGCTCACCTGCTAACTAGAAATAATATCATTGTACTGGTTTCGGTTATCTCACCATATCGAGTAATTCGAGAAGAAGTGAAAGCACAGATTGGAGATTTTATTGAAGTATACGTCAATGCACCACTAGAAGTTTGCGAACAGCGAGATGTTAAAGGTTTGTACAAAAAAGCCAGATTTGGTGAAATCACAAATTTCACTGGAATTGATGATTTATACGAAATACCTCTTAAACCTGATGTTGAATGCAAAACTGATCAAGAAAGTATTGCCGAAAGTGCAAATAAAATTTTAAATAAGCTAGAAGAGTTAGGGTACATCAATCCTCTATTATTGCCACAATTGCACAACAATTACTCGCGGATATAATGAATCGCTCTAATCAAAATACATTTATGATGAAATATCGTAGATTTGGGCGTACAGAATTGCTAATGCCAGTTTTTTCCTGTGGTGGAATGCGCTACATATATACTGAATATGAGGAACTGACTCAAGAAAAAATTCCTGATGAAAATCAACAGAATCTAGAAGCCACTATTCGCCATTCTTTAGAAGTTGGCATCAATCACATCGAAACTGCCCGAATGTATGGAACTTCTGAGATGCAATTAGGAGCGATTTTACCTAAGTTTCCTAGAGAAAAAATTATTGTGCAAACTAAGGTTGCTCCTACATCTGACTCTGAAGACTTCCGCCGTTTGTTTGAGAAATCTTTGGCTTTATTAAAGTTAGATTACATTGACTTATTAACATTGCATGGCATTAATTATGACCAACAATTTGAAGATAGTATTCGTCCTAATGGTTGTCTTGATGTAGCGCGACAATTGCAAGCTGAAGGTAAGGTAAAGTTTATTGGCTTTTCTACCCACGCCCCAACGGACTTAATTATCAAAACCATTGAAACCAATCAATTTGATTATGTCAATCTCCACTGGTACTACATTAATCAATTTAATTGGCCTGCTATTGAAGCCGCCACACGTCATGACATGGGGGTGTTTATCATTAGCCCATCAGATAAAGGTGGTATGCTTTATAAGCCTCCACAAAAGTTATTGGACTTGTGCTATCCACTGAGTCCGATGATGTTTAACGATCTTTTTTGTTTGAGCCATCCTCAAGTACATACTCTCAGCTTGGGCGCATCTAGACCATCAGATTTTGACGAACACTTGAAGGTTATAGAACTTTTAGACAAAGCAGATGAAATTTTACCACCAATTTTAAACCGTTTAGAAAAAGCAGCGATCGCCACATTAGGCAAAGACTGGTACTGTAACTGGCATATAGGTTTACCCAGATATCCCCAAACCCCTGGTGAGATTAATATTCCAGTTATTTTGTGGTTGCGAAATTTAGCGATCGCTTTTGATATGTGGGAATATGCCACAAGGCGCTACAACCACTTAAATAATGCCGATCCTTGGTTTCCTGGCGTGACAGCAGAACGAGTTAGACAATTCGATCTGGGCGATTGTCTGCGTCATAGTCCCTATGCTGACAAAATACCAGCTTTATTAGAAGATGCCCATAGGTTGTTAGCTAAACCTAGTCAAGAATAAATTGCGGAGTGGTTTCACGATGTCATATTATAAGTTATTAAAAAACAATAAAAAATATACTTTAATTCGTCATCGTTGGCTAGTAATTTTGCTGGCTTTAATAACTGCGATCGCAATAATTATTTCTAATCAAATTAACTTAAAAAATCAAGCAACAGCAATATCTCAAGTTATTGTCTCCTTCCCAATTGAACCCACAACTTTTAATCCAGCTTTAATCGTAGAATCAGCTTATACTTTAAACTATACTTATGAGGGGCTAGTTAAAGAAAATGGACGAGGAGAAATTGAACCTAGTCTTGCTGAATCTTGGCAAACTTCTCCAGATAAAAAACAAGTAATTTACACCCTCAGAAAAGGCCTAAAATGGTCAGATGGAAAGCCACTAACTGCTGAAGATGTGGTTTTTACCTACAATGAAATTTATACTAATCCAGCCATTCCTACTTATGCTAAAGACTTCTTCATAATTGGCAAAAATCGTACCTTTCCTACTGTTCGGAAACTTGATGATTTGCGAGTTGAATTTAGATTACCTGAACCATTTGCGCCATTTATCCGGGCTACAAAACTGGAAATTTTACCAGCCCATATTTTCCGAGAAAGCGTCAAAATAAAAGACCAGGAAGGCAGACCTAAATTTATGTCTACTTGGGGGATTGATACTCCACCAAAAAATATTATTGTTAACGGCCCTTATACAATAGAATCTTATACTCCCAGCCAGCGAATAATTTTCCGAAAAAATCCTTATTACTGGCGTAAAGATGCTCAAGGCAATTCGCAACCTTATATCGAGCGTGTGATTGGGGAAATTATTCCTAGTCAAGATACTTCTTTAATCCAATTCCGTTCTGGAGGATTGGATTACGTCAGCGTTAATACCAATTATTTTTCATTATTAAAACATGAAGAAGGCAAAGGAAAGTTTACTATCTATAATGGCGGTCTTTTTATAGGGTCAACTGCTATTACTTTTAATCTCAACAAAGGTAGTAGGAATGGTCAACCACTGGTCGATCCCATCAAGTCTCGTTGGTTTAATACAGTGGAATTTAGACAAGCAATTGCCTATGTAATTAATCGCCAACAAATACTTAACAATATCTATAAGGGATTGGGTCAACTGCAAAATTCACCGATTGCTGTACAGAGCAAGTATTATTTACCCGTCCAAGCAGGTTTAAAGGTCTATGAATACAATCTTCAAAAAGCGAAAGGATTACTGCTAAAAGCAGGTTTTAAATACAATAATCAAGGTCAGTTATTAGACGAGCAAGGAAATCTTGTGCGCTTTAGCCTCATGACGAATGCTAACAATAATATATTGCAGGCAATGGGAGTACTCATCAAACAAAATTTGAGTGATCTTGGCATAACTGTTGATTTCAATCCTGTAGCTACTAGTATTTTTATCAACAAACTAACTCAAACTTTCGATTGGGAGTGTCAAGTGCTTGAAGTTGCTGTCGGTCAAGAACCGAATGATTGGGCTAATGTTTGGTTGCCTGAAACTGGTTGGCACTTTTTTAATCAAAAATCCCAAGCAGGGCAAACGCCGATAGCGGGGCGACAGGTAGCAGATTGGGAACAGAAAATAGGTGATTTATACATTCAGGCAGCCTCAGAGGTGGATGAAGCAAAGCGTAAAGCTATCTATGCAGAAACCCAACAAATTACTCAGGAGTATCTGCCATTTATTTATCTAGTTAACCCTTTATCAATGGTGGCAGTACGAAATCGTATCCAGGGTATTCAACACTCTGCCCTCATAGGAACATTTTGGAACTCCTACGACCTGAAACTGACTGAAGATTAGCTAAAGAGGATATCGTTTGTATGCAAATTCCTATCATTGACTTCAATCCTTTTATTAATGGTGACACAGTTGCAAAAGAAGCTGTCGCTACACAAATTTCTCTTGCTATTCATGAGGTCGGATGTTTCTACCTCAAAAATTATGGTATTTCTAAGACTCTAATTACTCAAGTCTTTTCACAAGCCGAGTGCTTTTTTGCACTACCGGAGAATGAAAAAGAACAAGTATCTTTCTTTCCAGATCGTAATCTTCGCGGATATCATAATTTTAAAAAGAGTGAAGATAATCACAACGCCAATGAACTAATGACTGAAGGCTTTCATTTTGGTAAAGAAATTTCTCTAGATGAAGTTGGTATTATCGAAGATCCTTTTTTTGAACCGAATAAATGGCCTCATCAGACTAATTTTCGTGAAATGATGATGGAGTTTTTCACGGCTTGTCACGAAAGCGCTCTAAAAGTATTCCAAGCTTTGGCTATTTCCCTAAAATTGCCAGAAGACTACTTTACAAATTTATATTCAGAGCAAAATCACGGTATAGTTTGGCATCATTACCCATCTATATATCAGCCTCCAGAACTTGGAAAAGTTTATCTGGCAGAACATACCGACATAGGTACTCTCACATTTTTATTTCAAGATTCAGAAGGATTAGAAGTATATACAAATTCTGGAGAATGGGTTTTAGCGCCCTTCATTCCTGATGCAATTATTGTATTGGTTGCAGATTTAATGCAGCGATGGACGAACGATAAGTTTTGTGCCACACGACATCGAGTTGTAGTTCCAACTCAATCTCACAGTGCTAAACAAAGATACTCATGTGCCTTTTTTACAGGCCCCAATTACGATACTTCAATTAACTCCATTCAGACTTGCTTAGATATAGATGAAGTGCCTAAGTATCCACCAATTCTTGCCCATGAATATTTCAAGCAACCCAAATGATAGCCACGGATTAGAGATAATAAATGGACAAATTACAATTGCTAGCAAAGTCAAAACCTCCAACATGGTTAAAAATTTTGGTAATTAGCCTGATGGGGTTAGGTATTTTCTTTCGCTTCACCCATTTGGGGCAAAAAGTATATTGGTATGACGAATTTGCGACATCACTGGCAATATCTGGTCATACGCTAGCGGAGGTTAAACAAGAGGTTTTTAGCAATTGGAGCAATGATGGAGGCGTAATTCCTGTTATTACTTTAGACAAATATCAACACATTAACCCAGATCGGACTGTGGCTGATACAGTTCGCTACTTAATAACTTCAGACCCCCAACATCCACCTTTGTATTATGTAATGGTGAGATTGTGGGCGCAAGTCTTTGGAGATTTCCCTGCGGCAGTTAGGAGTTTATCAGCAGTAATCAGTCTGTTGATATTTCCTAGTGTGTATTGGTTGTGTTTAGAGTTATTTGAATCACCACTAGTAGGGTGGGTGGGAATGGCTGTAATGGGGATTTCTCCCTTACAGATTTTCTTTGCCCAAGATGCACGAGAATACGGTTTATGGATGGTGACAATTCTAGTATCAAGTGCTGCTTTATTGCGAGCTATTCGCCAGGAAAGTTCCTTGAGTTGGGCTGTGTATGCTCTCACCCTAGCCTTGGGATTCTACACCCATTTATTAACGGCAATGGTTGCGATCGCTCATGGCATTTATATAGTTATTAGGCAACAGTTTCGCTTCAACAAAACTCTGCGTAATTATTTACTGAGTTCCATAGTAGCTTCCTTGATGTTTTTACCCTGGCTAATGGTAATCATTACCCAGATTCACACAGCAACAAATCTCTTGTCATGGATAAAATTTAAAACAGATAGTCCTTTCGACCTGATTGGGATTTGGCTCAGTCGGATTAGCAGAATATTTTTTGATTTTAATTTGGCTTCTGATGATGCTTGGGTCAATAATTTACCTGCGGAAAGCCCTTTAACTTATAGTATTCCTACGATAATAGCTAGCTTATTTTTAATTATTTATATAATCATTTTTTTTATAAAATATCTCTCAACGAACGCTAGTTTATTTATTAGTTTATTAGGGGGATTTCCAGGGTTAACATTGCTTTTCTACGATCTAATTTTTGGGGGAATTCGCTCTATTCATTTTCGCTATCAGTTACCGTTATACATCAGCATCCAAATTGCTGTAGTGTATATTTTATCTTTCCATCTTTTATTGGCTAAGAACTGGCAGAAAAACTTTTGGAAAGTCATTGTGGTAGGGTTACTCATCTCTGGGCTAGTTTCTGATATCAGATTTTTTCAGTCTGAAACTTGGTGGCCACAAATAGGTGCTAAGAATTTGCTAGCAATGAGTCAACTTATTAATCAATCTAATAATAATATTTTATTGGTAAGTAGCAAAAATGATTATAACTTGGGAGTTATTCTCACCTTAAGTCATAATTTAGAGCCAAAAGTTCGCTTACTTACCATACAAAATGACCAGTTACCAATAATACCTCAAGACTATAAATCTATCTTCTTTGTTGACGACCTTGAAAATAGTTTAGCCCATCAACTTCAGCAGGATAAAACTAACTCACTTAAATTAGTCTACCCACTTGAAGGATTTTGGCAACTCGACAAAAATCAGAAAACGTGAAGATTACTTATTGTAGCAGTCTCAAATAAAAAACATTAAAAGAGTAGAAACTGAATGAAGCAATATCTTGAATATTTTAATATTATTTTTCTGATAGATAAAGTCTACTTTTATCTTCATTCGGCGCTTTTTAGTCGGTTTATTCGCTTTGCTGTAGTTGGTTTGAGTGGAGTATTTGTAGACTTGGGGGCATTCTATTTTTTACATAGCTCATTATGTTTAGCGTTAACTATGAGTGCAATGCTTTCTACAGAAATAGCAATTATCAATAATTTTCTGTGGAATGATTTATGGACGTTTGGCGATGTTTCTTTCCAACAAAAAATCAGTCAAAAGTTACAACGTTTTGTCAAGTTTAATCTCATTTGTTTAGTTGGGCTTATTTTCAATAGTCTAATTGTAAATTGGCTATTTTATCAATTCCAAGTGAATGAATACATCGCTAAATTGGTAGCGATCGCTTGTGTAACACTTTGGAATTTCTGGCTCAACCTGAAGATGAACTGGCAATTAACAAAAACAGAAGTAGATGTAGTTGTAGATATTTAAGAAAAAATCATGTTAAAACCACTAGTTATGTTTGGTTATAGTTTAATTTTTATAATTACTATAATTTTTTCTTCAGGATTCTTGAATGTAATTTTACCCTATTACAAGACTATCCAAAATCTTGGAGAAATCAGTGTTAAATGGCAATACTTGACTGAACACAAAGATGATTATGATGCTATTTTTCTGGGGCCAAGTACTACTTATTTTGGCGTGATCCCGAAATTGTTTGATGAATACCTGACGACAGAGAGGAAGAGTATAAAATCTTTCAACTTTGGTATAGCAGGTGCAAACGTATCAGAAGTGGATTTTTACTTACAAAAAATTCTGGAGTTAGAACCAGCAAACTTAAAGTGGATATTTCTAGACTGTTCAGTTGACTTATTTACAAACATTGGCTCTACTTCCGCTCAAGAGATATATTGGCATACTCCTCGTAAAACGTTAGAAAATTTCCAATTAATTTTGGAATCATCAATCGATAGTTGGAAAGTCAAAGTTCCATATATATACGCTAACTTTCAAAGCTTTATTTACCGATGGCTAGGAATTGGTCAGCTTTCTACTTTCTGGCAGGAAGCAATATTAAATTTGGATCTATCAAATTTAGATCCATTAGCAAAAGTATCTGAGGATAGGCTCATACAAGAATCGGGATATTACGCAATAGATTGGCAAGAAAAAGCTGAGAAGTGGAAGACTATATTTAGAGCAAATGGTTTGGATACTTATCAAAAGAATCTCAAAAATGAACAAACAAAATTAGCAAATTTAAATTCAGAAAATGCGTTTAACGAGCCATCCACAATATATGGAGCGAAAATGATGAAAAATATTGCTGCCCGGATTGAACAACAGCAAATTAACAACAAGAAAATGGAAGCTATATTTTTTATTCCTCCAATTCTAGAAGCCGATTCCAACCCATCCGCTATTTACAGAGCATACAAATCAGGAGATATCGATACTTTATTTACTTTTAATAATCCCAATGATTTTACTAATTTATATGAACTAGATCGCAGAATTGATAGCGCACATCTAAATTATCAAGGCGCTGAAGAATTCACACTTTTACTGGCATCACAATTTTCCCAGTATTTGAATAATTCTGGAGAAAAACTTATCAGTGGTAAACTTTGAATACCCAGTCATTATTACCTAATCACTAATTAAATATAAATATGGTATTCACAGAATTTCGATTTGTATTTTTCTTCTTGATTGTTTTCTGCATTTATTGGGCTTTGGAGAAACACAATCATCGTAAAGTGTGGCTGCTAGTTTGTAGTTATATCTTCTATAGTGCTTGGGATTGGCGCTTTCTTTTTTTGCTATTGCTATCAACAGTAATTGATTACTTTGTCGGTTTAATGCTATCTAGACCACAGGTTAGTGATTTGCAAGAGCAAGAAATTACCAAAATTGAGGTAGTACAAAAAGCAGAAACTACAAGCTTTTGGCATTGGGATGCCTTGCTGAATCAGCCACAGAATCAGCAGCAGCGCCAAGCATGGTTGATACTTAGTTTAGTAGCGAATTTAGGAATATTAGGGTTTTTTAAATACTATAATTTCTTTACTGATTCTGCTGCCAACTTATTAGCTTTTTTGGGTTTACCCCTAAGTATTAAAACCCTTAATATTATTTTGCCAGCAGGCATTAGTTTTTACACCTTTCAAACTCTGAGTTATTCCCTGGATATCTATCTAGGTAAACTCAAACCTGTGAGAAATTTTTGGGATTTTTCTCTATTTGTGACTTTTTTCCCGCAACTTGTTGCAGGCCCTATTGTCCGTGCGTCTACCTTTTTACCCCAACTGCTAACCCCAAAAAACTTTAACGATGTTGATGTTCGGGGATGTTTAATACTTTTTTTCGTAGGGTATTTTAAGAAAGCTTGCATTTCGGATAATCTTTCTCCTTTAGTAGAACAGTATTTCACAAATCCAGAAAATTATACTTTCTTAAGTTGTTGGATCGCTGTTATTTCTTTCGTCATCCAGATATACTGCGATTTTTCTGGTTATTCAGATATGGCGATCGCTTCAGCAGGGTTACTTGGATACAAACTACCTCTGAACTTTAATTTTCCCTACCTTTCCGGCAATATCACTGATTTGTGGCAACGTTGGCACATTACCCTCTACAGTTGGTTGCGAGATTATGTTTATATTCCTCTAATGAGAAAGCGACCAAAAGCTGAACGAACAGAACTATTTGGGTATAAAAATCTTCTCATTTTGATGCTTCTGTCAGGACTCTGGCATGGAGCTGCTTGGCATTTTGTAGTTTGGGGTGGATTAAATGGATTCGCTTTAGTTGTTCACAAGCAATGGTTATCTCGGATCGCTCCCTATAAGGGATTGCTAACACTGAGAAAGATGCTAGGTATTCCCTTAACAATGTATTGGTTTTGTGCATCTGCCGTCTTCTTTCGGAGTAACGATCTCAGCAGTGCCATACAAATAGAAAAATCCTTTTTATTCTTGAATTCTCTTGGCTCTCAAAACCTAAATCTCCAAGTTGCATGGATTTTTGCACCTTTAATTATGCTCCACTGGGCAGCTTATAAAGGTTGGTTTGCCGATTGGTGGCGTAAAATTCCTAGTTGGAGTTTTGCTGTTTGCTTTGGGGTTTTAGTTTCAGCAATATTTCGGCTGACAGCAATCAATCCTCAACCTTTTGTCTACTTTCAGTTTTAGCGTGCGATCGCTTGTTGCAAAAAGAATACCTTTTAAATTACCGCCATCAATTAGAGAGATATGACAACAATTTACTTACATATTGGAATGCCCAAGACTGGAACAACTTGCCTACAAAAAGCATTATTTAATAACAGGAATAAACTTTTAGAAAATGGTTATTTATATCCTGGCTCTGGCATCAAATACAACGCAAAGGAAATAGTGAACCGTTACTGTCATAATACTTTAGCACATTATTTAATGGGTTTTGAAAATAAGGATAATGCACTTTCACAATTTACAGTTTGGGAAGAACTGAAAAGAGAAATAGACTCTATCAATCCTAAAAATGTGATAATTTCCGCAGAAGCTTTTACTTCTTTTGAAATCTTTTATCAACCGGAAACACTTGCAAAAATAAAAAACTTCTTAAAAGAATATAAAATCAAGATAGTTATCTATCTAAGAAAGCAAGATGAGTTTTTAGAATCTTCTTACTGTTACATGGTTAAACTAGGAGCTTGTAGCGTAGGAATTAAAGAGTTGTTTAATGAATACCAGTACATATTTAATTATTATCAAATACTAGACAATTGGGCAGATATATTTGGATATGAAAATATTATTGTTCGGCGTTTTGAAAAGTCAAACATGAAAACTCATATTTTTGATGATTTCTTAGGAGTAATTAACCAATTCGACAATAAAAGTGATTATCAAATTGATTATGCTGCAAAAATAAATGTGTCTCCTTCAGGCAAAACTATCAAAATGCTTTTGCTTATAAATAAGTTTAATGAAACAACTTTAGCAAGATTTCTAAAACTAGATGATAACTATTGGTCAAAATATCAAGATTTTTTGGATTTTTTATCCAATAACAAAACAATAAATAAATTTGTATCAAAACTACCCAACTTTTTAGTTGATAATGTGCTTCTATCATCGGAAGAAAAGCAAGATTTTATGAGACAATTCAAAGAATTAAATAGTCAGGTTGCTAACAAGTATTTAGGTCAAAAAGATGGAATATTATTTGGCGATTATTCCTAGTTATATAACAATATGATTAAGTTAAGGAAATTTATCTATTAAGGCAGTGGAAACAGGGGGGAGAAAAAAGCTTAACTGAACGGTATTGAGTTATATAAATCTGATTTGATGACTGTAGCATAGGGAAGAAAATCTTATCCGAGGAACAAAAAAATGGATAAACAGGTGTACCTAGCTTTTAAAAAATCAAATATTAGTCCTATATGAACAAGCTGCAAATAATTAAAAATAAAAATATTGAATCTATTTACCCTCTTTCTCCTATGCAGCAGGGTATGCTTTTTCATACTCTGTATGAGCCAGAATCAGGAGTATATCTTGAGCAGTTCTGTCTAATGCTCTCTGGAAATCTAGATATTACAGTGCTTCAGCAGGCCTGTGTGCGAGTAATGAAGCGTCACCCAGTTCTGCGTACCCTTGTGGTTTGGGAAAAACAAGAAAAGCCTCTCCAGGTAGTATGTAAACAAGTGGAGTTGCCTTGGCAGAACTATGATTGGCGTTCCTTATCTTTAGCAGAACAAGAAGAGCGTTTAAAAGCTTTCTTACAAGCAGATCGAGTTCAAGGCTTCGTTCTTGACAAAGCTCCACTTATGCGATTTAGCTTAATTCAAATCGCTGATGATATTTACGAATTTGTCTGGAGCTTTCATCACCTGCTGATTGATGGTTGGAGTTGGCCAATTCTCTGCAAAGAAGTTTTTGCATTCTACAATGCCTTACTTAAAGGCAAATATTTATATTTAAATACTCCCCGTCCTTACCGAGATTACATCAATTGGTTACAGCAACAAGATTTAAGAGCAGCAGAAGCTTTTTGGCGGCAACAACTTCATGGTTTTACTAGCCCTACCCGTTTGCTACTAAATCGGGGTGAGGCGCACAATTTACAACAACCAAAAACCTATCACGAGCAGCACTGCTGTTTATCGGCAACTATAACTGCTGCTTTACAATCCCAGGCACAGCAGTATCATCTGACACTTTCAACTTTCGTCCAAGCAGCTTGGGCACTTTTACTCAGTCGCTACACTGATGAGTCTGAGGTAGTATTTGGAGCAACTGTATCGGGTCGTCCTCCCACTCTATCGGGGGTGGAATCTATGGTGGGACTATTCATTAATACTTTACCAGTCAGGGTGAAAGTACCAACAGCAACTCCTTTATGGCAATGGCTGAGGGAATTGCAGGCTCAACAGGTAGAGCGATCGCAATATTCTTGGTTTCCATTAGTAGAAATTCAAGCTCTTAGTGAAATTCCCCCAGAATTACCTTTGTTTGAAAGCATTGTGGTGTTTGAGAACTACCCACACGATCCGTCTTTATCAAATCTAGGTAGCACCATCCAGATTACCAAACGGCGAGTCATTGAACAAACCAATTATCCGCTCACAGTCATCGCTGTACCAGGACAAGAGTTATCCCTACGCATTCTTTATGATGGTAGCTGCTTTGATGCTGAAACGATTAACCGGATGATGGGGCATCTTGTGACTTTGTTAGAGGGTATGAGCGCTAACGTCGAGCAGACAGTAGCAGAGATATCCATGCTAACTACCACTGAGCAACGCCAAATCTTAGTATGGAATGATACTCAAAAGGATTATCCTCAAAAATGTATCGCTCAGTTGTTTGAAGAACAGGTGGAACGGACACCGGATGCAGTAGCAGTCTCATTCCAATCTCAACAACTGACTTACCAACAGTTAAATTGTCAGGCGAATCAGTTAGCGCACCATCTCCAAAAACTTGGGGTAAAACCAGAAGTGCGGGTAGGGATTTGCGTTGAGCGTTCTTTATTGATGGTAGTAAGACTTTTGGCAATCCTCAAAGCTGGTGGTGCTTATGTACCTTTAGATCCGCGATCGCCCCAAGAACGCTTAACTTATATGTTGAGTGATTCTCAAGCGTCGATGTTGCTGACAGATTCATCAATTACTTTATCTGAGCAACCATTAACAGTAGTTTGCTTAGATACATCGGATTTCTGCCAAAACAGTCAGGAAAATCCTGTTAATGGAGTGATACCAGGGAACTTGGCTTATGTCATGTATACTTCTGGCTCAACCGGCAAACCCAAAGGTGTAGCCATGAGTCACCGTTCTCTGGTGAATCTTTTATATTGGCAAATGGACGAAATTTCTTTAAGTTGTGCTAAAACTTTGCAATTTGCTTCCATCAGTTTCGATGTCTCTTTTCAAGAAATCTTCTCTACCTGGTGTAACGGCGGAACCTTAGTTTTAATCACCGAAAAACTACAAAAAGATGGGTTCGCATTATTACAGTTAATTGCCCAAGAAAAGGTGGAAAGACTGTTTTTGCCCTTTGTCGCCCTTCAGCAATTAGCCCATGCTGCCTCTATTACTCAATTATATCCTGCATCTTTGCGTCAGATTATGACGGCAGGAGAACAGTTACATATTACCCCTGTTTTAGTCAACTTTTTTAAGGAGCTTTCTGGTTGTACGCTACAAAATCAGTATGGCCCAACGGAGAGCCATGTAGTAACAAGTTTTACTTTAAAAGATGTGGCAAGCAGTTGGTCGCCACTTCCGCCTATTGGTCGGGCGATCGCAAATACGCAAATCTACATCCTTGACCGCCATCTGCAACCATTACCAATTGGAGTTCCTGGAGAACTGTATATCGGCGGTGTTGCGATCGCTAGAAGTTACATTAATTCCCCGGAATTGACAGCTGAGAAATTCATTGCAAAAAATGGGAATCGTTTGTATAAGACAGGCGATCGCGCTCGATATTTATCTGATGGCAACATCGAATTTCTCGGTCGAATTGACAATCAAGTGAAGGTGCGGGGTTTTCGCATTGAACTGGGAGAAATTGAAACCGTACTCGCCGCACACCCCCAGGTAAAAGAAGCAGTAGTTATCGCCAGAGAAGATGAACCAGGAAACAAGCGTCTAGTCGCCTACATTGTCCCCAAACAACACTTAGACACCAGCGAACTGCTTTGTTACCTCAAACAAAAGTTACCCGAATATATGCTACCTTCTGCTTTTGTAAAGTTGCTGGATGCTCTACCTCTAACCCCCAGTGGTAAAATAGAGCGCCGCGCTTTACCAGCACCTTTGAGTCGGGAAACACGGAACATCTCTACAGACTTGATTCCACCCCGTACTGTTACTGAAGAGGTTCTGGCAGGAATCTGGAGCGATGTTTTAGGACTAGAAAAAGTTGGTATCCATGACAACTTCTTTGCATTAGGAGGTCATTCTTTGTCAGCAATGCAAGTCATTGCTCGGTTGCGAGAAATCTTCAAAGTGGAGTTACCCATAAGTTGTCTGTTTGATTACCCGACAGTAATTGAGCTAAATCGGCAAATTTCAGAATACCGCCAAAAAGAGGCAGGGGAGCAGGGGAGCAGGGGAGCAGGGGAGCAGGGGAGAAATAATCATTCTTTCTCATCCCCCTGTGCCCCTCTGCCCTCTTGTAAAAATGACTTGACCCCATTTCTCAAACCAGTACCTCGAAACACAAAAGAGTTGCCAATTTCTTTGACTCAGCTTGAGTTTTGGATATTAGCTCAATTGCATCCGGGTATTCCCGTCTATAATATTCCACTGGCTTATCGCTTGACGGGTTTACTCAACGTCACTGCTTTAGCACAAAGCCTCGTGGAAATTGTCCGTCGTCACGAAGCTTTGCGAACTACTTTTGCGATCGCAGATCGGCAAGTAGTTCAGAAAATTGCTCAACAGCCCATATTGCCATTTTCGGTGGTAGATTTGCGAAAACTTTCTGAATCTAAAACTGAGCGAAAGGCTCTGGCTCAAAAATTTATCACTGAGGAAAAAAACCAGCCTTTCGATCTAGAACAAGAACCTTTGTTACGCATCAAGCTACTGCGGCTCTCTGATGCCGAGCATTTACTAATAATAACTATCCATCATCTGGTTTGTGATGGTTGGTCTGTGGGTGTGTTTTTACAGGAGCTAACAAAATTATACGCAGCATTTTGTCATGGTCAACCTTCACCGCTTCCTGATTTACCCATCCAATATGCTGACTTTGCCCATTGGCAAAAGCAGTGGGTTGCTCGTCCTGCTTTCGTGTCTGACCTTAACTATTGGAAGCAGCAACTAAGCAATAGCACACTTTTACTACAGTTACCTACTGACCGTCCGCGCTTACCAGTACGAACTTTTGAGGGTGCAAGTCAAACTTTCATCATCCCTAAGAGCCTAACAAATGCTCTTAAACATCTGAGCCAACAGCACAATGTAACTCTATTCGTGACTCTACTAACAGCCTTTAAAATAGTGCTATTTTATTACACCGGACAGTCAGATATTATTGTGGGCACTCCCTTTGCCAATCGCCAGCAAGTGGAAACTAAAGGGCTTATTGGATGCTTCATCAACACATTACCAATACGTACACATTTGGGAGGTGATCCAAGTTTGAGCGAGTTGCTGTATCAGGTGCGTGGATCTTTTTTAGCAGCCTCCGATCGACAACAAATTCCCTTCGTGAAGTTAGTAGAAGCACTACAGCCAAAACGAGAACCAAGCCATTCTTTGCTATATCAAGTGATGTTTAACTTCTTGCCACCATCAGATTTAAAACTGACAAATTTGACTGTTCATCCCTGGTCAATTGAAAGTAAAACAGCAGAGTTTGATTGGGATATTTATCTTCAACAAACAACATTAGGAAGTATTGAAGGGAAATGGTGCTACAAAATCGATTTGTTTGATGCTTCTACTATTAGTCGTGCGGTAACTCAGTTTCTAGTGTTGCTTGAGTTGCTAATTACTAATCCAGAATGTCGTCTGACTGACCTTTCCTTACTATTTCAGCGCCATAATTCTCAATGCCGTGCAATGTAGGTACATATAAGAGGTTGTTTGAAAAGTGTTTCGCTGTGACTTTAGGCACTTTTAGATCCCCCCTAGCCCTTAAAAAGGGGGGAACCGGAATCAAAGTCCCCCTTAAAAAGGGGGATTTAGGGGGATCTAAAACTTTTGATACCGGCAATAGAACTTTTCAAACATCCTCTAAGAGCAGGGAGCAGGGGCAACAGAACAAGAATAGGTGTAATTAATTCTGTTTAGGTACTTAACTTATATGTCAGATGTACAGATTATGGAAAAAACAAGGCTAACTGTTTTACGGGAAATGCGGCTGTTTATCATTGTTTGGGTAGGACAGTTGATCGCCTTAATTGGTTCGAGTACCACTGCCTTTGCCTTAGATATCTGGGTTTATAATCGCACCGGTTCAGTTACCCAGTTTGCTTTAGTCTCTCTGTTCAATACTCTCCCGCTAATCTTAATTTCCCCGATCGCTGGGCCTCTGGTAGATAAGTGGGATCGCCGAAAGACAATGATTATCGCTGATGTCTTGGCGTGTTTGGGAACAATTGCGATCGGCGTTTTATTTGTCATCGGTCGGTTAGAAGTCTGGCACATTTACCTAGCCAATACCTTCACTGCTGTTTTCATGGCTTTTCACACACCTGCTTATACAGCATCAACAGTCTTACTAGTGCCGAAACAGCACCTTAATCGTGCCAATGGGCTAATGAGTCTGATGTTTGGCATTTCGCTGATCGTTGCACCAACTCTCGGAGGTGTTCTACTAAGCATTGTCCATTTGCAAGGAATTATTTTGTTTCACGTAAGCGCTGTATTTATTGCTGTTGTTTCCCTGATGCTGGTTCGGTTCCCGGAAGTCAACACAAGTGCTGTTGCAACTGCAAAAAGTTCATTCCTAAGTGAAGCAACTTACGGATTGACATATTTGATCGCTCGACCAGGACTGCTGGGACTAGTATTATTCTCAGCTTCCAGCTTTTATATTGTGGGAGGTATTAATGTCATCACTATCCCGCTAGTCTTAAATTTCGTTTCAGTCAGCTTTTTGGGAACTATTCTTTCGCTATTTGGCATTGCGATCGTAGCAGGTGGCTTGCTTGTCAGCATCTGGGGAGGGCTAGAACGCAACATATATGCCATATACGGGTGTATGCTTTTGAGTGGCGTATTTATTTTCGTCGCCGGTTTGCAACCCTCTCTTGTCATTTTCACTGTTGGTATCTTCTTATTTTTCCTAACACAACCGATCGTTTCCAGTTCCACGCAAGCTGTCATGCAAAATAAAGTAGAACCTAATGTACAAGGTAGAGTTTTTGCGATCAAAGGAGCGATTGAAGCAGCCGCTTTCCCTTTAGGCTACATCACGATTGGGCCTTTAGCCGAGAAAGTTTTTGAACCCTTAATGGCTACTAACGGTTTTTTAGCAGGAAGCATCGGACAAATCATCGGTGTTGGGTCAGGTCGTGGGATGGGACTTCTACTGATGATTATGGGAGTCTTGACCATTTTAGAAACCTCTATTGCCTACTTGTACCCTCGCTTACGGTTTGTGGAAGATGAACTGCCTAATGTTAGTAATGCAGTTGCAATGGCTGCTGATACAGCTTCTAGTAAGAATGACGCAGTTTCTTTGATATCCTAAATTTGGCGTTGCATAGTGGTGGTTGATTAAAAACTCTACTAATTTGCAATTATTATTTTATTTTCGGAATTTTCGATTTTTGAAAATTGGTAATTGTTAACTTAGTCTATAAATCGGAAAATTTTTGTATCTAGATTCAAGATTTCTACTCTAGATTAAATCCTGTGTTTTTTCATCAGTTAGTATTTTTGTATTTCAATCAAAAAAGATGTTCAGCTTATTTTAGAATATGCAAACCAAAGTTTCTCGCGGTCAATCCTTAAAGAATGATCCTTCTCCTCCGGCCTCTAATAATTTTTGGGAGAATGTAAGAGCGATCGTTCAGCCTTACTGGTACCCAACAGAGTCAGGGGAAAGAGTATTTCCAGACGTGATTCGGATATGGGGGATGCTGATTCTCCTGATTTTATTAATAATAGCGCTAGTCGGGGTAACTGCCTTTAATAGCTTCGTTACTCGCTATATAACCGATGTCATTGAAGAGAAAGATTATCCTAACTTTATTAATACGATAGTAGTTTTCGGCGCTGCTCTTGTCTGCATAACACTCTTAAACGGATTTTCTAAACTTGTCAGAAAAAAAATCGCTCTTGATTGGTACAAATGGTTAAATAATCACATATTATCAAAATATTTGAGCAATCGTTCCTATTATAAAATTAACTTTAGAGCTGATGTTGATAACCCAGATCAACGAATATCCCAAGAAATCGAACCCATTACCAGTAATGCTCTGACTTTTTCAGCTACTTTCCTAGAAAAAGTGCTGGAAATGATTACTTTTTTAGTAATTCTTTGGTCAATTTCCCAATTTATTGCAATTGTTTTGGTTGTTTATACAATCGTAGGCAACTTGATTGCTATTTACTTAGGTCAACAATTAAATAAAATTAATCAAGAAGAATTAGAACTGAAAGCAGAATACAGTTATTCTCTGACTCATGTTCGTAATCACGCTGAATCGATAGCTTTTTTTCAGGGAGAAAAGCAAGAATTTAATATAATTCAACGAAGATTTATTAATCTCCTGAAAAATGTCGAACGCAAGATTAATTGGGAGAACAATCAAGAACTTTTTGACGGAGCATATAAGTCTGCTATCCAAATATTCCCATATCTGGTACTCGCACCTTTATATATGAGCGGTCAAGCTGATTTCGGAGAAGTTGTCCAAGCCAGTGTAGCTTGTAATCAGTTTGCCTCGGCTATGGCAACATTAATTAGAGAATTTGGGACTTCTGGACGATTTTCCAGTTATGTTGAGCGTTTATCTGAGTTTTCAGATGCGTTAGAAGCAGTTACCAAACAACCAGAGAATGTCAGTACTATTAAAACAATAGAAGAAAACCGTTTAGCTTTCGAGAATGTCACATTACAAACGCCAAACTATGAACAGGTAATCGTTGAAAATTTATCACTTTCTGTTCAACCAGGAGAAGGCTTATTGATTGTTGGGCCGAGTGGACGAGGTAAAAGTTCTCTGTTGAGAGCGATCGCAGGTTTGTGGAATGCGGGAACGGGTCGTTTGGTACGACCTCCCCTAAAAGAAGTATTATTCTTACCCCAACGGCCTTATATCATTTTAGGGACTTTGCGCGAACAGTTACTTTATCCTAATACGAATCGTCAAATGACCGACGCAGAACTCAAAGACGTTTTGCAACAAGTAAACTTGCAAAACTTACTAAGTCGAGTTGAAGGCTTTGACACTGAAGTTCCTTGGGAAAATATATTATCGATAGGAGAACAACAACGTCTTGCTTTCGCACGACTGTTAGTTACTCATCCGAGCTTTACTATATTGGATGAAGCAACAAGTGCTTTAGATTTGAAAAATGAAGGAAGTTTATATCAACAGTTACAATCAACGAAAACAACATTTATTAGTGTTGGGCACCGGGAAAGCCTGTTTGATTACCATCAATGGGTTTTAGAACTTGCACAAGATTCCAGTTGGCAACTTGTAACTGTCCAGGATTATCGAAATCAAAAAGCAAGTATAACTAAATTTCCGTCAAATACTCAAATCAAAATAAATGATTCGCCTGAAGACAAAGCGCAAAATGAGTCAAAAATCAGCACAGGCGAAAAACTTACTCATAAGGCAATGAATGAATTAACATCCTATTCACTTAGCACGATTAGAAGCAAGGCAAGCAAAGGAGAATTTATCACTACTAAGGACGGTATTATTTATCGCTATGATAAAGATCCCAATGTTTTGAAATGGGTTTTAGTTTAGCCATCACTCATACTTTTTGAAATTGTAAATTATTTCCATTGGGAGATTAAAGCGTCCTAGTCCAAGCTGCGACTGTAAATCCCAAGTAAAAGAAAGTGACAAAGAAGCAGAGCGAAAAGTCTGCCAACATTCAAACTACCCAACCAACGGGTGAGAATGCTGAGACAACCCAAACTCAGGAAAGCAAAGTTTCAGCCAATATCCAAAAGTGGGAACAACCGCAAACATAAACTCAGGAGCGATCGCTAAAAACTATGAATACGAAAGCTAATGCCAAATATAAAATCCTTGCTATAGATGGTGGTGAGAGTCGGGGCATCATCTCAGCACTAGTACTAGCAGAAATTGAAAAGAGTATTAATTTTATGTGAGTCTCCAACGGAGGCGCACGTTAATTTTTGGGGTGAAATGTTTTGATATCGATTTCGGTTTTCAGTACAGTTGGATCATCTGTGTGTTGAATACGAAAACCTAGTTTTTCACAAACTTTTTGCATACCATAATTGTCAACCAAAATATCAGCAGTGATAGTGCTGAGTTGCTCATCTCGACTGACTTGCAGTAACCTTTGTAGTAACTCGGTTCCTATACCTTGGCACTGATAGCGATCGCACACCACAATAGCAAATTCTGCTTCATTCGTACCATGTATTTTACTTAACCGCCCGACTGCCAATATTTGCCGTGTCTGCGTTTCGGGGTTTTGATATTCGACAACTAGGGCTATTTCGCGATCGTAATCAATAAAGCAGATACGTGTTAGGCGTTCATGGGCTACTCTTGACTGGAGTTTAATTAAGTGAAAATACCTGAAATAAACACTTTGCTCTGAGAGTGTCTTATGAAATTGCACCATCAACGGCTCATCTTCTGGACGGATGGGACGGATGGTAACTGGAGTGCCATCTTTCATCGTCCATTTGCTGACATATTGTGTAGGATATGGTCGAATTGCTAACTTTGGTAGTTGGTCTTTTTTAACATCTGGTTCATGAAGGATAATCCGCGCATCGAGGGCAATTAATTGTTCAGATGAAGCCAGCAACGGGTTAATATCGATTTCCTTAATCCAACGCTGTTCTACAACTAATTGACTAAATACCACCATTAATTGTTCAAGGGCAGCCATATCAACACTTTTGCGTCCCCGGACTCCTTTCAGCGCTTTGTAAATCTGCGTTTGCTCCATCATGCGCCGCACTAAAGTTGTATTCAGGGGTGGAAGTGCGATCGCGCGATCGTGAAAAACTTCGACTAGTTGTCCTCCTGTGCCAAAAAGCAACACCGGGCCAAACTGTGCATCCAGACTACTGCCGATAATCAATTCATAACCGGCCATTTTTACCATCGGCTGCACAGTTACACCTAAGAAGAGTGCTGAGTACTGAGTACTGAGTGCTGAGTAATGAGGGTCGTGTTGCAATTTATCCTGTAAAGAGGATTTAATGTTGCGGTAGGCTTGTCGTACAGCTTCAGCATCTCTTAGATTTAACTGCACACCGCCAACATCAGTTTTATGAGTGATTATCTCGGAAAACAGCTTTAAAACAACTGGATAACCAATTTTTTCAGCACATTGAACTGCTTCATCCTCGCTTTTAGAAACGCAAGTTGCAACCACCGGAATCCCATAAGCAGCTAAAATTTGCTTCGATTCAAACTCTGTAAGAATAGTTCGCTGTGTCTGACGTGCTGATTGGATAATTTTTTCCACACAGTTACGGTCTGGTATCCCTGATGAAGAATCAAGTGCAGGCATTATGGGAGTTTCGTAGATACCGCGCAGGTTATAACTAGACTGCCACATATAACTAAATATTCGAGCAGCAGTATCAGGATAAGGATATGTGGGAATATGGTTGCGATTGAGAATCATCTCACCTGCTGCAATATCTGCTCCTCCCATCCAACTAGCAAGGATGGGTTTACCAGCTATCTGTGCATAAGGTTTCAATTGCTCGGCTGTTTGGGTGGGGTCTGTCATCGCTTGAGGCGTGAGAATCACCAATAACCCGTCACTATTTGGGTCTTTAGCAGCAATTTCTAAGGCTTTGGTATATCGCTGTGGGTCAGCGTCGCCCAGAATATCAATCGGGTTGCCGTGACTCCAATGTGCTGGTAATAGTTGATTCAGAGATGCGCTAGTTTCTTCAGAAATTGGTGCAACTTCTCCACCCGCAGCAATCAAAGCATCAATGGCAAGGACTCCAGGACCACCTGCGTTAGTTAAAATTGTCAGGCGTGGCCCTTGGGGACGGGGTTGTTTTGCCAGCACCTCTGCCATATCGAACAAGTCAGAGATGCTGTTGACGCGCAACACCCCACAACGCCGGAAAGCTGCATCCAGAACTTCATCACTTCCTGTAAGTGCGCCAGTATGGGAAGCTGCTGCTTTGGCTGCGGCTTCAGTGCGACCTGCTTTGATGACAATAATCGGTTTAGTTAAAGCAACTTCTCGCGCTGCTGACAAAAACGATCGCGCATTCCCAATTGATTCCATGTAAATGACAATACTTTTGGTGTGCGGGTCATCACCCAGGTAGTAAATCAAATCTCCCCAACCCACATCTAGCATTGAGCCAAGAGAAACAAAGGCGCTAAAACCAACGTTTTCCCGAAAACTCCAATCTAGGATAGCCGTACAAAGCGCTCCACTTTGACTAATGAAGCCGACATTTCCAGGACGTGCCATTGTACTGGCAAAAGTTGCATTTAAACCTGTGCGTGGACTCATTACACCCAAGCAATTAGGGCCAATAATCCGCATTTTGCCACGCTGCGCTTGCTCAAGTATTTGCTGTTCTAAGGCTACACCCTCAGCACCAGCTTCTTTAAAACCAGCACTAAGGATAATTGCACCTTTGATACCTGCATCCACGCACTCGGCAATAATACCTGGAACTGTTGTTGCGGGGGTAGCAATAACTGCTAAATCCACTTTTTCGGGTACATCAAAGATATTGGGGTATGCTTTGATTCCCAATATACTGTGCCGTTTGGGATTGACAGGGAAAACAGTTCCACCAAAAGGATTGCTAATCAAGTTCCATAATAGAGTACGCCCAACACTACCAGCTTTTTCACTAGCACCAATTACAGCAACACTTTTTGGTACAAAGATCGCATCAAGGGGATTTGCTTTCTCGGTTCGCAAAATATCATAGGCGCGATTGCTGGATGATTGGATAGGCTTTTGCATGAGTTGCTGTTACCTGTAGTGGAAATATATTTTAAAGAAGTAAGCTGAAATTTTCGTCTATAATTTGGGTAATTTTTTGTAAAGCGATCGCTACTCCAATTTCAGCAAATGGTGATAAGCTGTAGCCTAATTCAAAATTTACTCCTGGTACTTTTATCCACCAAGCTTGTGGACAACGATTATAAAGTGCTTGAGTGAGAGCTAAGAGCGATCGCGGATCGGCTGTATGTCCGGCAATAATGTTGAAAGATTCAGATGAAAGCGATTGTACCTGTACCTGGGAACTTTCAGAGGTGAAACAAGCATCGATAAAGATTGCCAAATCAGCATGGGCTAAAGCTTCAGCAAGTTCAGGGGTGAGTTGATGGACAGCCAGAGATTTCACGTTTGATAGATGCAACGCCTTAGCTACTCGTTGCCCAATGCCATCATCACTACGCAACTCATTACCATAGCCAATTGCGTAGGCGTAGCCCGTCGTAGACATCGCTTCCGGCAAAGCGTAGCCCATCGCATTAGAATTCATATTTTTAGCTGTCCAACACTATTTTAAAGTTAGATAAAAAACTTGAGAAACTTGTGAGGAGATAGAGAAACTTGGAAGTAATGCTCACAATTTCCTCAGATTGTTGACATATAAATAAAACTGTGAAGCAATATTACATCCCCTAATATGACTTAACGTGAAGTGAATTCGACGGCTCATATAGTATCTGTCTACTTAGCTGAATCAAAAGACCTCTCCCTGATTTTACTACGCAAAACCTTTCCTCTCCGACTCGGAGAGGGACAGACTTGAACTTTAGTTCAAGGCAGGGAGAGGTTCATTGGAAGCTCACGTTAGCCTGAGATTTTTGACGCAACATCCCCCAGTTCCCTGATACTTCCTGCTTTTTTGCGGGTATCTGAATCTGAGTCCTGACAAAATTTAAGTTGTAATAAACACTGTATTTCCTCACAAGTTCCTCAAATTCTTTTTCTAACTTCAAGATAAAGATGCCCAACTATTGCATTAAATTAGCTTGAAAATTTGTGAGCCAAAAAAGATAGGTCAAGCAAAATAAATAGGCATCTGCCAAAAGTAGTGAGAAATTTTTGAACTTGGAGTTACTTAGGAGATACACACCATGAGTACCATTGTTCAACCTCAAAGAGAATTTAATTTTTTTGATTTCTGGGATAGTTTTTGTCGCTGGATTACTAGTACAGAAAATCGGATTTATATCGGCTGGTTTGGTGTGTTGGCGATTCCCACCTTATTGGCTGCCACCACCTGTTTTATTTTGGCTTTTATTGCCGCTCCCGGCGTAGATATGGATGGCATTCGTGAGCCAATCATGGGTTCACTGATGGATGGTAATAACTTAATTACAGCCGCAGTTGTACCGACCTCTGCTGCCATTGGTTTGCACTTTTATCCGATCTGGGACGCGGCATCAATGGATGAATGGCTCTACAATGGTGGGCCATATCAATTAATTGTGCTGCATTTTCTTATTGGTATTTGGTGCTATCTAGGGCGATTTTGGGAACTGAGCTATCGTTTGGGAATGCGCGCCTGGATAGCAATTGCCTATTCTGCACCCGTCATCGCTGCTACTTCCGTTTTGCTAGTTTATCCTATTGGTCAAGGTAGTTTTTCTGATGGTTTACCTTTGGGAATCACTGGAACTTTCCACTTTATGTTGGCTTTCCAAGGTGATCACAATATCCTTATGCACCCGTTTCACATGTTGGGTGTAGCAGGTATATTCAGTGGCGCACTATTTAGTTCTTTACATGGTTCTTTGGTGACTTCAACACTCATTCGAAAGACCGATGACAATGAATCAATTAATGCCGGATATAAGTTGGGTCAGAAGAAATTTACCTACAAGTACTTAGCAGGACACTCTAGCTTTTTGGGACGGTTGTTGATTCCTATCTTTGCTAGTAAAAATCATCGTGCTTTCCATTTATTATTAGCAGCATTCCCAACGATAGGTATTTGGTTTGCAGCGATGGGTGTATGTTCGATGGCGTTTAATATCAATGGGTTGAACTTTAATCATTCCATCTTAGATAGTCGGGGTGAAGTAATTAGAACCAATGCTGATATCCTGAACCGTGCCAATCTGGGTATAAATGCAATGCACGCTCCTAACGTCCATAATTTCCCTTTAGTTTTGTCTAGTGGTCAACCTATTCCAGTTAGTTAAAGATTGCATCCATCCATTTTTATAGTGGTTTTAAACCTGCCTGTAATTCTGGTATTAGTCAATATTGCAGGCAGGTTTTTCATCAGAAGAATTTTGAATGAGGTACTAAAAAGTCAAGTGTTCTTTTTCCTTGCTTTCTTGTCTTGGTGAATTTTAGGTATTTATTTCTCCAGAGGTTTTAGTTTTAAAGGATACAATGGCTCAGATCCATTTAATTGCCAAATTCTAAATACCAATACAGCAGCTACAGTTAGCCATACACAAGAAAATGATAAAGTCATTCCCGCTACAGGATTAGTTTGCCAATAAATTGCCGTCACTACTACAGCAGATAACCAAGGGCCTAAAATAACTACAGGAACAGCAGCACCTAATCTCCGTTCTACAGTAAAAATCGTATTCCAAGTATCCCCTAAAGCCAGATGTACCACAAACAAAATTAAAGGCAGCACTAAAAATTGATGATTCATTTGCTGCCAAACCAATACAGAAGAAATTACCCGCAAAACGGCAATTATCATCCAAACAATGGGAAATACTAAAGGTGGAGGAGACCATCTTGGTCTAATTACCTGGTCATAAGTCTGACGAGAACGGGTATTATCTAAAAGAGAAAAAATTCGGGAACGGATACTTAAGAGAGCAAAAAATAATCCAGTCAATAAAGTGCTAAACCAACTGGGAAAAGAAGAATTACTATCAATTAACATTACTATTTTTTCCATTCCCAGTAAGACGAGAATCATAACTACTATTTGTAGGATAGTTCCTAGTGTATAAACTAAAATTGCTCTGACATCTAGTTCTTGTGTAGTAGCTATTGATGTATCTCGATACTGTTGTTGATTCCCAGCTTTTACTCCCATCACTGTATTGACAAACTGTTCAAGGATTCCACTATTATTGGATTGATTCATAATTAAGAGATTGTGCCTAGTTTGTAATTAGTAACAATAGGTGATTATATCGCTATTCCATTACTCTAGGCAGAGGAAAATAAGAAATCTTTAGATTCAGAGGTATCTGGAATAGAATCTCGCATTCGATTCATTAATTCAGTTATTGGTTAGTAATCCAATCGATACCAGCCGTAGTATTAATTCATAATTTTGCACTAGAACTTAGTGGCAAAAATTTCCAGTTTGTTTCTCTGGGGATTGATTGAATGAAGCGGCATTAAAACTTAATAACGCGTTTCTTGTTTTTTCTTTAACTGTCTTATCTGTCCTTGCATTCTCGCTTTAATCCTGAGAATATATTCAAATTGATATACCAACTTGTAATTTACAAGTAAAAAGAAACCATGAAAAAAATACTATTGTGCTGTTGTGCAATGATTTTAGCAATGTGGGTCGCCATCAACCCTGCACTCGCTGCTGATAGCAAAAGTCCTGCACCTGCTACGGATAGCAACAGCACTGCACTGGCTGGCGATTGTACTGAGGTGGGATTTTTTCCCAATGAGCAGGACTGCACCAAATTCTTCCGTTGCGTAGATTTTGGCGATGGTAGAGACTTAACAAAGTTCGACTTTGACTGTGGGCCGGGGACTGTTTTCGATGACCGATACGATACCTGTAACCATGCTTGGGCGCTCCCTTCCGATTCTACATGCTACAAGCCTATGGAAAGCATGAAATAGTAAGAAACGGAGTCCGCGATGTCTACTGCGTACTACACCTATGCCCAGGGAAAATACACCTAAAATCGGTTCGTTAACTATCTGAAGCTCACATTACTCTACTATCAATAGGTAGTGATAAGTTGCGCGACCATTCATTCCAAGAGCCAAAATAATTTCTGGCAGAAATCCCTGCTTCTTCAAGGGCTATTAATGTATTCGCAGCCCTTGAACCCTTAAAGCAGTAAATATACACAATGGACTCTGAAGTAATATCTACTGAGTTACAAATTTCTCGGATTTCATCTGGCGATCGCAACGTGGGGATTTTGGAATACAAATTACAGAAGAAGAAATGTTGAATGTTACGAGATAATTTTTGTGGTTGTGTTGTTTTAAAGGAAGAATTCAGAATAGATTAATCTCGCCAAACTTCATTTACAATATTCCCATCTGTCCCAATTAATTGAATATGCAAAGGCATTTGTCCTGCCGCATGAGTTGAACAACTCAAACAAGGATCAAAAGCTCTGATTCCCGCCTCAACGCGGTTTAACATCCCTTCAGCAATTTCTGAACCGTGAATAAAATGTCGGGCAATTTGCGCGACTGTACGATTCATTGCTAAATTATTCTGACCTGTGGCAATTACTAAATTTACTTTCTGAAGTAACCCATTTTCATCAACTTGATAATGGTGAAATAATGTACCGCGTGGTGCTTCACTTACACCTACTCCTTCTCGTTGGTTGATGCCAGCATCAGCACGCAATTTTTTAGACATTAAATCTGGGTCATCTATTATAATTTCTATGCGTTCAATGCAAGCCAGAATTTCAATTAACCGGGCGTAGTGATAGAAAAATGATGAAGTGACAGTGCCTTGACCTCTGTCTCTAAATTCTCTCAATTCTGTATCAGCTAAAGGCGTACCAATATGACTGCAAATATTCAGGCGTGCTAGCGGCCCTACCCGATAAATACCACTATCTAAACGACAATGGTCGCTCTGGTCAGGATAACCTAAAGGGCGATAGTAAGGAGACTTTAAATAGGAATCTGGTTGAACTGCTTCACCAATAAATTCTTGATAATGAGTTGGATCAAGTTTATCGGCAATAATATTTCCCGCGCTGTCTACAAAACGAATATGTCCGTCGTAGTTCTCCCACAAACCATCAGGAGTGACTAAACCCATAAATAAACTAGGAAAATTCCCGAAAGTTTGCACTTCTCTTTGATAATCATTGAGTAAGTCTTTAAATCTACCAAGTGCATCTAATATTATGGTGCGTGCTTCTGGAATGCGGTTTTGAATATGGGTGCGTCCTTCTATCGATAAGGGTTCGCGGACACCACCAGGAACTGCCCATGATGGATGTATCTTTCGCCCTCCCAATTGTTCGATAATTTCTTGTCCAAATTGACGCAAGCGAATTCCGCCACGCGCTAATTCTGGTTCGGCTGCAATTAAGCCAAATACATTGCGTTTTTTGGGGTCGCTATCCATTCCTAATAATAAATCTGGGGCGCTGAGGTGGAAAAAACTCAGGGCGTGGGATTGGATAATTTGTCCCAAATTCATCAAACGGCGCAGTTTTTCCGCAGCTTTGGGAATTGTAACTGCAAGGATGCGATCGCCTGCCTTTGCTGATGCTAACAAATGGCTTACCGGACAAATCCCACAAATTCGCGCCGTAATTCCTGGCATTTCCCACAAAGGGCGACCCTCGCAGAACTTTTCAAAACCACGAAATTCTGTGACATGAAAACGAGCATCGCTCACTTGTCCTGTATCATCCAGATAAATACTGATTTTGGCGTGTCCTTCAATTCGGGTAACTGGGTTGATGATTACTTTTTTCATAACTATCTCAGGTCAACCACTAGTAGTTCGCTTTCGTGACTTGGCGGGGTAAAGGGAAAGGGGGAAGGGGGAAAGGGTTTAAATCCCTTACCCTTTCCCCTTTCCCCTTTCCCCAGTCCTCACTTAGCATTTTTGGGTTGGCAGACTACTAGACCAGTTGTCATAAATTCCTTTAGCTTCTGGATATTCGTCGCAGTATTCTTCAAAGGCTGTTTTCACGACTTTCTCGGCCCTTTGATGTGCGATCTCGGCTTGTAATTCCTCGATCGCATCCCAAACAACAGCACATTCTTCTGAATGGATACCTTGGCGATCGCAAATGACACGAGCTTTTTGAATTTCGTCCTGAAGTTGTTGTTCTAGCAGGAAAGTATGGGGTTGCTCAAGAAAGCTACTATTAGCTAGAATGTCAACCAGGGAAATGATACCCAGTAGTTCGCCCTGAATAACGGGCGCTCTCTGCAAATTATGGTCAGCAAATAACCGCGCTACGTATTCTAAGGCAAGTTCAGGATTGACAACGATACAAGGCTTGGTCATCACTTCATGAACACGCACACTAAAGGGATCTTTACCATAAGCAATCACTTTATATACAATATCCTTTTCAGTAATCATGCCGTAGGCATCGTGTTCATGGCGGCGATCTACAACCAGCGCTTTCCAGTCCCTTGCTCTCAAGAGTCTAACTGCTTCAGCCACTGTTGCTGAACTGTGAATTGTAGCAACATCTCTAGTCATAATGTCAGATGCTTTCAACATAATTGCTTCTAAAATTATTTTGTGATTGCCTCTCTTTCAACTTAGATAAAGAATCTGAGTAACTTGTGAAGTTAACCAAACTTGATAAATTCACGTCCTTTTAACCGTGGTTTTTCTCCCCTTAAGAGTGCCTCTAACACTGCTTTAATCTGAGTTGCTGAGGGTGGGCAACCTGGTAAATAAATATCAACTGGCACTACTGTATGCACTGGTATCACCCGATCTAGTAAGGTTGGTACAATGCCAGGCTCATAGGGAATAGTGCCGTGAATATCTGCTGCTTCGATGTAACAACGTTGCAGAACAGGTTCGGCACTACCTAAAGGATTGCGTAAAGCAGTAACATTACCAGTAACAGCACAATCACCAAAAGAGACAAGAATGTGCGATCGCTCTCTGACTATCTGAATCATTTGCAGGTGATCTTCATTAGCAATTGCACCCTCAACTAGCACCACATCTACCCCTGGAGGATATTCTTTAGCATCAGCAAAGGGACTATAAACTAAATCTACTTGTGCTGCTAAATCAATCAGCCATTCATCCAAATCGAGAAAAGACATGTGACAGCCAGAACAGCCGCCTAGCCAAACCGTTGCTAATTTTAAACGAGTCATTTTATTTTTTAAATGAATTTTGACCTTAGAGGTTGTTTGAAAAGTATTTCGCTGTGACTTTAGACACTTTTAGATCCCCCCTAACCCCCCTTAAAAAAGGGGGAACCGGAGTCAAAGTCCCCCTTTTTAAGGGGAGCCAGTGCGGTCTTGGGGGTTTCCCCCATGAGCAACTGGCGTGGATTTAGGGGGATCTAGAATGTTTTACTACCAAGAAGAGGACTTTTCAAACATCCTCTTAGCACTCAGGACTTTAATGCAATTTCTTGCCATTCCTGCACGACATATTTTGGGATTGAAATATTGATGAAGTGTTGTTTACCTACAGGTATACCAATCAACAATTCTTGAGTTGATAATTGAGGCAAAACATCCTTTAAGTCATACTGAGCGATGGTTGGTGCTGGTGCTTCATCTAGGAATATATCGGGAGCAGTTAATACTTTACCTGTATCTGTAGTAATCTTTAGGGGTAAGGGATGGGGCAATTCCTGAGAACCAGGAAATCCCACCAATCGGAGATTTATTGAAGATATTTTATTGCTATTAGAATTAACTCGCTTAAACAAAATAACTTGCCAATAATTTCCTAATTCATCATTTAATTTTTCTTGTGAGCGATAAAGGATTTCTTCTGGCGTATCTTCTAATTGCATAACAGCAGCAATTACCTGTTGAGATGTGAAGCTTGCTAAACCCAGGTATATATATATTGTTAATATTGCCAGCAATAGGAGCCACCAAAAAATTTTTAGGATGCGGCGTAACATTAGGTTTACCTCGTTGTGCTAATTTATGAACAGTAGCTAAACAAGCCATTGCTGCTTTTCTCTTGCTGTAAGTAGGAAATCAAGCTTGGCGCGATCGTGTTTCATTTCCCCGACGCTCGAACCTTTGTCAAAAAGCGCACCTGTAGGGCAAGCATTAACGCATTTGCCGCAAGAAGTACAAGTATTTGAGGTTCCCCAAGGCTGATTTAAATCAGTGATCACATGAGAATTTGTCCCTCTACCCGCCATATCCCAAGTGTGCGCTCCTTCGATTTCGTCACAAACACGGATGCAACGAGTGCAAAGAACACAACGGTTATGGTCAACGCCAAAGCGAGCGTGAGAAATATCGACTTTGCGATCGGGGAAATGATAATCTAAACGCACATGATCCATACCCATCTCAATTGCCAAGTCTTGCAATTCGCAATTACCGTTAGCTACGCAGACCGAGCAAATGTGATTACCTTCAGCAAATAGCATTTCTATAATGGTGCGACGATATTTTTGCAGGCGATCGCTATTTGTTTGGACTTCCATACCCTCAGCAACTTTTGTTACACAAGCAGGTTGGAGTTTATTACTCCCAGCAATTTCTACTAAACAAAGCCGACAAGCGCCAACATCTTCGACTCCTTGCAAGTGGCACAAAGTAGGAATGTGAATCCCTGCATCTTGCACCGCTTGGAGAATAGTTTCTTCCTCACGGGCGCTAATCAGTTTGTCGTTGACTGTTAAAGTTTTGACTGACATTGCCTCTAGCCTCAATCAGAATAAGCCTTTCGCTTCTGAAATGCCCTGAGTCTTGAATTGTAGACAAATAGTTTGAGGAACTTGTGAATAGCTTGGATAGTTTTATCATCAATTACTTTCCAAGCTATAGGAATCCGCTTTGATTTTTGTATCCCTCACGGGAGCGTAGCCATACTTACTTGCGTGGGAAGGAAAGAGGCAAGAGGGCTTTTTAAGTTGTAGGGAGTTTTTGCAAAAATCAAATATGAGTCTATGCAAAGCAGAAAGTAGCCAGAAAATTTACATATCTGCAATTATTTTGAATTGAATTAAATTAACGTGAGTTCGATGAACCTCTCCCTCCCAGCCTCCCTCTCCGAAACGGAAAGGGAGGTGCAACGAAAAATTCAGCTTTTTGCTCCCCTCTCCGTGTCGGAGAGGGGTTGGGGGAGAGGTCAAATAAGACTTGTCGAACTCACGTTAAATTATGTCCACTAAGAAATTATTTCCAGGAATTATTCATTAGCGGCACGTTCAAACACTACTGAAAGATTATTGGCTGGCATTTGGTAAATTTGTTTCAAGATGAAATGTTCTGCCCTAGCTTCTGCCACTACATCATCCAAGTTCCGCACGCCCCACTCCTGGTTTTGGGTGTGTAAATATTCGTCAAAAGCTGCATTACTCGCTGCTGTATGTTCTCCACCTTGTTTGAAGGGCCCATATAAATAGAGGATACCTCCTGCTTTTAGGATACGGCCTGCCCCTGCCATTAGCCCCAAACAGGCTGACCACGGTGAAATGTGAATCATATTAATATTGACTATCGCAACTATTGGCTCCCTATTAAGCCACTCAGTTACTTCCCCTTTCTCCACTGCCCAAACTGGCTCTCTAACATCTAGCTCAAGCGGTGGATAAACATTATCAGAGGCATTGTGTTCAGTCCATGCACTAATGCTGGCTCGTAACTCTAAATTTGCATCTGTTGGTAGCCACAGGCGAGGACTTAGCCTGGATGCAAAAAAGACTGCGTGTTCACCAGTACCACTTGCTATTTCTAAAATAGTGCCACTTTCGGGTAATACCTGCAAAAGTATTTCTAGAATTGGTTCTCGGTTGCGCTCAGTTGCTGGTGCGTATTGTCGTGCGTCTTGTGGTGTCATTCTTATCGTGATATTTTATAATTTTTCTCGCATGTGCGCTTTCCGATAGTAACAATATAGATGATCTGACCTATGCCCATTCGAATTGTAGCGACTGTCTTAAAAGTCAAGCGATCGTTAACAAAAAAACGTGGGTTGGAGCATTGACGCAACAGAGGAACGCTGCGCTAGATTCGGCGGTGTCTGGTACGGGCTAGAAGACTTATGGCTTGTAGTCTAGATAGTCAAAGCCCGCACCAGACACTCCGCTTCGCCGCCGAATCTTCCTCGGTTGCTGGATTTCTCGTGTAGGCAAAAACAGCATGAAAAATTTACCCCAGTTATAGGGGAGCATCAATGCGGATGCCGTACATTGCTGGCTCTGGGCATCAAGCAAAGTATAAAAAGGTTGACTTGTGATTAAACATTGACAATTGGTTTAAAGTTGTCAGTTAGACACCAAGGCAAATTATCTCGAACCATTGCATTTAAAATGACTAACATCTTATGAACGCAAGCAGTTAGGGCCAATTTTTTGGATTTACCACGTTCGACAAGGCGCTGATAAAAGGCTTTGATAACGGGATTATGACGCATAGCAACCACAGCACCCATATAAAGAGTCGCTCGAACATGGGCACGACCACCATTAATCATCCGCTTACCTTTGTGTTGACCACTATCATGATTGATCGGTGCAACACCAACTAAACGAGAGATTTGTTTGGCAGTTAATTGACCGAGTTCTGGTAAGTCAGAAACGAGGGTAGTAGAAATAACTTGACCAATACCAGGAGTAGTTTTGAGTAAATTGACTTTATCAATCCATTGTTGATTATTTTGCGTCAATTCCTGAATTTGTTGATTGAGCTGTTTGAGACGCTCTTCAAGATATTCAATATGAGCCTCAATATCTGCTAATGCTTTACCACGGGCACGCGCCCGACGATTTTTCTCAGCAGTCTGCATCTCGACTAACTGTCTTCTGCGACTAATTAATTCGCCCAGTTGACGCGCTGTTTCAGATTCAATTGCTAACACCTGGGGTTTCATTGCTTCCCCAAAGTGTGCCAAAATTTGTGCATCAATAGCATCAGTTTTTGCCAACCGACCTGTGGCTTTCGCAAAATCTCTTCCAAGGCGTGGATTAATTAATGCTACTGGTAAAAGTGCTGCCTGCAATTGGATAATAAGTTCTGTTTCTAATCCTCCTGTTGCTTCTAACACAATCAGATTTAAATCAAATGATTTGAGTTGTTCTACTAGATGAGATATTTCTACTTCTGTATTAGCAACTTTCAATGCTTTACCCATTGGACGGATATAAACATCGAGAGTTGCTTTACTCACATCAATGCCTACCCATTGAGAAATATTTTCCATATTTCACTCTCAACTAATTTCTGTACCCTGTTTTGAATTCATCCCCTTGATTTAACTCATCCTTGCCCGATACGGACTGTATACTTTAAATATCAGCGTTTAAAGCTTTGACCCCGGCGACTGTTCGAGTTCTGTCAAAGAGATTGTTGTAGTGACCCATGCTACGAAGCGGTCTATTATGACCAAGGTTGGGACGGTCTACTACTATTTCTAAGATACAAGGTTGGGTGGAGGCTTTGCGTAACCCAACATCCTGATATATGTTGGGTTGCGCTCCGCTCCACCCAACCTACGTCTAATGCACTATTTTGTGTAGACAGTCCACTACGTGCATTTCAAAAATAAAATACTAGTTCTATAGTGATCTTCCCGATAATAACAATATAGATGAGTTGACCTATGTCCATTACAGTAATTCTTGACAAAAAAAGTATCCATAGTTCATGTATTATCACTAGATACGTTCTTTTCGTATTGACAAAACAACTTTGACAATTACATTTTAAACCTTAAACTTACATACGTGTTTCATGGCTCGTAAAAAATCATCTCCATTACAATCAACTGAAGTAACTCCATTAGCCCTCTCTCAATTACATATCCGCTTGGAGTTTTTAGAAGCAGAACACAAATCGCTACTTAAACAGATTAAGAGAAAGCGAACGGAATTGAACAATTTTGTCGAGCAAATGCGAACTTTTGCCACAGAAATATTTCATCAAGCTAGTCCCCACGTTCAAAAAATGGCTGAGTTAGACCGAGATATTCATGCTCTATTTGATGAAATTTTTACCACTAGAAAGTTTGGGAAACAAACCATCAAAAATATAGAGGCAGTTTACCTTGAACTCCAGTTGACAGGGATTATTAGTCCAAACGCGAATCGTAAACAATTCAATACAGAGTTAAACGAACTATTTAATAATTCCGAATCCGAATCAGATTTTTCAGAGGAAGCGGCTGAAGATAGCCATCAATATTGGCAAGCACAACAGTCTGTGGAATCTCCCTCTGTAGCGAGAACAGAGGATAAGAGAAAAATTCGGGAAACATTTCTCAGATTAGCTGAAATCTTTCACCCTGATAAGACAAGAGACAGCGAGACACAGATATATCATACAGAAATCATGAAATCAATTAATAAAGCTTACCAAGAAGGAGATTTGGCAAGACTTTTAGAAATTGAGCGAATTCAGCAGGTGGGAGAAGTTATTGATCTTAATAACGAGGATGATTTAACTCGCAAATGTCGAACTATAGAACAGCAAAATCAAATTCTCGTCACTCAATATGAAAACTTGAAACTGGAACTACGTTTAGTAAAAAATACTCCAGAAGGAACTATGGTAAGTGATTCTCGTAAAGCTGCGAAAAAAGGCATTGATTCTATGTCTTTGATGCTAAAAACAATAGAATCTCAAATAAATGTTATTTCTCAAATCCGGGATTTTGTCAAGGACTTTAGAGAGCAGAAGATTACTATCAAAGAATTTCTCGGTGGGCCACCAACCCCACACTCCTTAGACGAAGAAATTATGGAAGATATTCTTGAACAGATGTTGTCAGAATTAATGAGATAGTACAGTTTAACTTAACTGACTCCGAAATTTATGAACACTAATAGTTAATAAAACAATAGCAAAACCAAGCAATGCGAGAACATTCAACCACAGCACATCTAAACCAACTCCTTTGAGTAAAATACCTCTAACAATAGTAATGTAATGACGAAGTGGATTAAGTAAAGAGAGAAATTGAAATAAAGGAGGCATGGATTCAATAGGAGATATTGCCCCAGAAGTTTGGATCATTGGTAAATTTATAAAAAAAGATGTGAGTAATACTTGTTGTTGAGAACCGCAGATAGTTGCTAGCATAATTCCTAAACTAATTCCCACAAATACATACATACTTGATAAAGCGAGAAAGAGCAGGAAACTCCCACGAAAGGGTAGGCTAAATACGACTGTTCCCAAGGTTAAAGCTAGTAGCACATCTCCCATGAGTAGGAATGCCAACGGGATAATTTTAGCTAATAAAATTTCCCAGTTGCTAGAGGGAGTCATTAACAATTGCTCTAAAGTTCCTGTATCTTTCTCGCGTACATACAGTTACTGCTGATACTAATGTACCGATTAATGTCAGGACTAAACCCATAACTCCCGGTACGAAAAACCAACTACTTGTTAGTCCAGGATTGTAAAGAAAAACGACTTCGGTTGAAACTGGCGGACTGACTTGACCCTGTACCAAACTGAAACTATATTGTTGGATAATCTGATTAACATAGTTAGCAGCAATTCCGGCTGTATTTGCATTCACTCCATCGATAAATACTTGAATTTCTGCTGATTTTTTAGCTAGTTGGCGGGGAAAATTTGGTGGAATTATTAGTCCTACATCTAGCTTACCTTCTTCTACTTGACGGCTTAAATCTTTTTCACTTGTTGGTACAGATTCTAAGTTAAAAGTATGATTGGATGTCATTGCTGAAACTAGTTCTCGACTGGCGGAGACATTGGCATAGTCAATTACACCCAGTCGTAAATTATGGACATCCGGGTTGAGTGCAAATCCGTAAAGCAATAATTGTACTGTTGGTGGCACAATTAATAAAACAATCAATTGCCTGTTTCACATAATTTGATTAATTTCTTTACACACTAATGGCCACAATGGACTATCAAATAATTGCCAAATATATTTCATATATGATTAAGAGGTTGTTTGAAAAGTGGTTGGCTGTGGTTTTAGGCACTTATTGATCCCCCCTAACCCCCCTTAAAAAAGGGGGGAACCGGAATCAAAGTCCCCCTTTTTAAGGGGGATTTAGGGGGATCTAAAACGTTTTGCTAATGACCAATGACTATTGACTAATTTGCATTCGACTTAAAAGCCGACGCGCTACGTTGAAAAATACAAATCCCAAAACTGCAAGCATGAGTAAGTCAAATCAAACTCCTGTCCATCCTGTACCACGCACAAAAGCATCACGGGTGATATCAATGTAATAACGCGCAGGAAATACGTTAGGTGTTAGTGAAAGGGGAAAAGGAATATTACTCAGGGGATAAATAAAAACAGATAGCAATAAAGATGTAATAAAACCGACAAGAGAAACAATTTGTACTGCGGAATTTTGGTTACTGCTACGTACCCCTCCAAGTAAACCAAAGGAAACACTATCTATTAAAAAGAGTAGAGTTCCTATTAATAAAGTGATCGGGTTACTAATTACGCCGATATGAAAAATTATTGACCCTAATCCCATAACTATTAAAGCTTCTGTAATCGCAATTAGCAGGTAAGCTAATCCTTTGCTAAGTAACAGTTCGGTTGCACTAATGCTAGAAGCCTAGACTTGTAAAATTGTACCTTTTTCTTTTTCACGCACCATTGCGATCGCTGTTAGCAATGAGGGAAAAATCCACAATACTACAGCATAGGCTCCTGGCACAATGTACAGCGACTCCAATCTACCAGGGTTAAACCACAAGCGGATTCGCGGTGTAATAATATTTTTATCTGGTAGTAGTCCTTGGTCTTGCATGAAAAAATTATAGCGGTTCTCAGTTGGGTGCAATATAGTAACAGCAGTGCGTGAACCATCCAATAATATCTTTTTTAGTCACAGCATTTAAGGCATTTGTAATGGCCTCATCTAGCTCTTGATAGGTTCGAGCGGCTTGCGAACGTAAAAATTCTTTCACCTTTGACCAGCAGTTTTCAATCGGTGAAAAATCTGGAGAGTAGGGAGACAAATAAACCAATTTTGCTCCCACAGATTCAATGGCTTCACGGATACCTGTAACTTTATGAGAACTGAAGTTATCCATAACAACAGTTGCACCCGGCTTCATGCTAGGAACTAAAACTTGAGTAACATAGGTTTCAAACGCCGATGCATTAGTACCACCAGTAAAAGTCATCGCAGCAATGATGCCTTCAGTTGACATCGCTCCAATCATCGTCACATTTTTTCCCCGGCCGTCAGGACAATGACCATAAGCACGACTACCTTGAGGCGAACGAGCGAAGCGTCTGGTCATAGCAATATTTACTCCAGCTTCATCGATAAATACTAAGTCTGCTAAGTTTACTTCTCCGATGATTGTCCAATACTCTGCCCTCAATTTTTGCACCCGTTCTGTATACTTTTCGCTCGCGTGTAATGTTTTTTTTTGCGTGTCAGATTCAGCTTTTGGGTGATTCTGCCCATTGAGGAACGGCTTATCTTTACTTGAGTCTGTTGTTCTAAGCGATCGCACAATTCCACCAAAGTGGCATCATTATCTGACTCTACTAATAACCCTACCAATGCCAGATGCTCATTATTGAGCTTTGAGATTTGACCTCCACCATGAGGTTTTGGCTCAACTGTCCCACTGCTACGATATCGTCTCAGTAAACTTTGAACAAAACTCAAGCTGACACTGAATCTTATTGCCAATTGTCGTTGAGAGCCTTCTTGATTGTTATATGCATTGATCACTTTTTGGCGCAGATCACAAGAGTAAGGTTTCATTCCCTAAATACTTAGACGTTAATATACTCCATTATCTCATACTGTATTTCACTCAAGCAGGAACCGCTATATATCTTTTTTCCTTCCGACTTCTGCCTTCTGCCCTCTGCCCTCTGCCTTCCCCCAACCTAGATCACCAAAAGTTGCCAAGAACCAAATTATGATTCAAAGGACACTTCAGGCAGTTGCGACTCCGGTTTCCGTAGCACTAGCCATACTGCACGACGAGGCGTGAGACAAAGTTTTTTGGGTTGAGTGACTTTTGGTAAAGACTTAACTGAATACAGTTTTCGTGGCTTGATTCCAAGGGCTGTACGGATGCGCCGCGTGTAACGCGCTACAGTATCATAACTACCTTTGTAACCCTGTTGTTGAATTTCCTCAAACAAGACTAAGCCTTCGTGACAACCTTCATTCCAGCGTTTTAGGATATATTCTTGGTATGGAACTAAAATACTTCGACCTCGGCTTCTTCGCCGAGTTGGTTCAACAAAGGTGGGAGTACGTAGATAGCGAAATACACTTGTTACACCAATCCCAACTTGACGGGCTATAGCTTTTCCACTCCAACCTTGATCATGTAGATCCCAAACTTGCTGATGAATAGCAACTCGTCTAGCACGGCTTTGTTCTGCTAATTGTAGTGCCTGTTGTTCACGGCTTGGTCGTGGTACTCGCACAACTACAGTACCGTCGGTTTGGGTTACTGATGAAAGACTGTATGAACCTATCCCACTAATAAAATTCTTTGAATCCAGATATGAATAGTAGCAAGGTCAATGATCGATCTCGTGAGACGACTTTGACACCGGGATGAGCTTTTAACCATTCTGCTAAGGTTTCAGCTTTTGCATCTTTGAGTAGAGCAATTGGTCGGCTGCGTTCCAGGTCAATTAGTGCTGTGCCGTAGGTTTTACATTTACGAAAACAAAAGTCGTCTACCCCAAGAGTATGTGGCGTTACGATTGGTGGGAGTGGGATTGAGCGGACTAAATTTAATAGTGTGTTGCGAGAAACTTTTATCCCTAATTGCTCCGAGAGTCTTACCCCTGCTGCACCACCATTAGCTAAAGCAATCGCACTTAGTCGTTGAGCTAAACGTAGAGTCCTTCGCGCCCAAGGTGCGGTTACACTGTTGAGCCTTTCGGTAAAAATGCGTCGGTTACACAAAGTATTGATGCAAAAAAACTTCCGCACCCGTAACTGTAGGGTAATGCTGTAATCAGCCCACGGTAAGTCTGCTAACTTCCGCTCGTAGTGGCTATGAATTCGGTGAGTTGGTTGATTACAAACTGGACAATTAACTACTGTTATGATTGCAGAAACAATCAACTTTATCTGAGTTTTTATTTCGTCAACAAGGCAACTCTCAAGTTTCAGGTTTGTTGAATCTGGTAAGAGGCGAGTTAGCACCGACAT

Protein sequences of DBSCAN-SWA_2

>NZ_CP046703|553986:640842|609332_610853_+|WP_114084445.1|DBSCAN-SWA
MVFTEFRFVFFFLIVFCIYWALEKHNHRKVWLLVCSYIFYSAWDWRFLFLLLLSTVIDYFVGLMLSRPQVSDLQEQEITKIEVVQKAETTSFWHWDALLNQPQNQQQRQAWLILSLVANLGILGFFKYYNFFTDSAANLLAFLGLPLSIKTLNIILPAGISFYTFQTLSYSLDIYLGKLKPVRNFWDFSLFVTFFPQLVAGPIVRASTFLPQLLTPKNFNDVDVRGCLILFFVGYFKKACISDNLSPLVEQYFTNPENYTFLSCWIAVISFVIQIYCDFSGYSDMAIASAGLLGYKLPLNFNFPYLSGNITDLWQRWHITLYSWLRDYVYIPLMRKRPKAERTELFGYKNLLILMLLSGLWHGAAWHFVVWGGLNGFALVVHKQWLSRIAPYKGLLTLRKMLGIPLTMYWFCASAVFFRSNDLSSAIQIEKSFLFLNSLGSQNLNLQVAWIFAPLIMLHWAAYKGWFADWWRKIPSWSFAVCFGVLVSAIFRLTAINPQPFVYFQF
>NZ_CP046703|553986:640842|624933_626004_+|WP_114084452.1|DBSCAN-SWA
MSTIVQPQREFNFFDFWDSFCRWITSTENRIYIGWFGVLAIPTLLAATTCFILAFIAAPGVDMDGIREPIMGSLMDGNNLITAAVVPTSAAIGLHFYPIWDAASMDEWLYNGGPYQLIVLHFLIGIWCYLGRFWELSYRLGMRAWIAIAYSAPVIAATSVLLVYPIGQGSFSDGLPLGITGTFHFMLAFQGDHNILMHPFHMLGVAGIFSGALFSSLHGSLVTSTLIRKTDDNESINAGYKLGQKKFTYKYLAGHSSFLGRLLIPIFASKNHRAFHLLLAAFPTIGIWFAAMGVCSMAFNINGLNFNHSILDSRGEVIRTNADILNRANLGINAMHAPNVHNFPLVLSSGQPIPVS
>NZ_CP046703|553986:640842|567332_569252_-|WP_114084423.1|DBSCAN-SWA
MTNKTIQHPERWTRDYIFDILRQIGIHYIFGVPGTNEIPIIDGTSYPENEVQYIECLHENIAIGAAMGSARMSGKPGVVVVHVTPGIAHSIGNLFNAWRSHVPLVILCCQQQNELVTQEPLLASNLVDLARQYTKWAHEVRTPEEIGLVLQRAFKEAIAPPNGPVMVAIPWEFTMRHIDAEDRIPGITQISPHFTGDSSTIQQAALLLAEARNPIIIAGDAVGYANAWPELQDLTELLGAPVLLQTFSSVANFPNDDFHWQGELPGTQLGMQQVFQDHDVAFFCGFGLQAQITVFKYSDGPLIPPSVQQIYLTNNTWDIGKNSYSQVGILGDIKTTLPLINNLVRQNPPAEAVKRNENLRQLNVQRHQQWQQYLELALTKDEIWAVVIADALRKAIQERGLEKQFVYVHEAVSDPAPFQYFLPLGNDGAVPISYYCVAGGSLGWSMPASLGIKLESFGWQGIETRLVVNAVGDGSSLFYPQTWWTAAHRELGILYIITNNQEYQTLQSGLQQVVAAYSSAPGYGWKPKTNDPEYLRIERPKLDFVALAKAFGGQDGEIVETSQDVSSAVRRGIDYVLKTRRSYILDVRTAKDTLSTPLTQQMSARYTAQPPLNFFHRQVEKSFLRTQAPGAAVNVPIIF
>NZ_CP046703|553986:640842|556729_560365_-|WP_114084417.1|DBSCAN-SWA
MNKRSFATIDGNEAVAQVVYRLNEVIAIYPITPSSPMAEWADTWASESKPNIWGTVPSVVEMQSEGGVAGAVHGALQTGSLTTTFTASQGLLLMIPNMYKIAGELTPTVFHIATRSLAAQALSIFGDHSDVMAARGTGFAMLCAASVQEAQDFALIATRATLESRIPFLHFFDGFRTSHEINKVETLTEDDLREFIPNELVFAHRSRALTPDKPVLRGTTQNPDVYFQARETVNPYYLACADITQKVMDEFAAMTGRQYQLFEYHGDSEAERVIVLMGSGCEAVHETVNYLNANGEKVGVLKVRLYRPYDAMRFVTALPATTRSIAVLDRTKEPGASGEPLYLDVVTALYEVWGTGEKLGLDSPLPLRPSVTERSRSADFLPQVVGGRYGLSSKEFTPAMIKAVFDNLAAAEPKNHFTIGINDDVTYTSLNYDPDFSIEPDTTVRAIFYGLGADGTVGANKNSIKIIGEETNNYAQGYFVYDSKKSGSVTVSHLRFGSQLIRSTYLISKANFVACHQWEFIEKFPILKDIVPGGTFLVNSPYEKDEVWNHLPPSVQEQIIQKHLKFYVINAYKVARQAGMAGRINTVMQVCFFALSGVLPREEAIAEIKNSIRKSYGKKGDEIVQMNLKVVDTTLENLFEVGNRELGIGNGKGKQSPILDAAPPFVRDVLGKMIVREGDELPVSALPADGTYPTGTAKWEKRNIAQEIPVWDTDVCIQCGKCIMVCPHSVIRSKVYEPQQLENAPLMFKSTNAKDHDWQGFKYTIQVAAEDCTGCGICVDVCPAKNKSELRRKAINMEPQRPLREQERENWDFFLSIPNPDRSHLKLTHINQQQMQEPLFEFSGACAGCGETPYIKLATQLFGDRMIVANATGCSSIYGGNLPTTPWTHNAAGRGPAWSNSLFEDNAEFGLGFRISIDKQAEFAAELLKYLITDVGEELANSILNAEQKDEADIWEQRERIELLKKRLDEIVNHQPNPNQKSKIQNLKSLADYLVKKSVWIIGGDGWGYDIGFGGLDHVLASGHNVNILILDTEVYSNTGGQMSKATPKAAVAKFASGGKAAPKKDLGLMAMTYGNVYIASVAMGARDEHTLKAFLEAEAYQGPSLIIAYSHCIAHGINMSTAMQNQKAAVDSGQWLLYRFNPDRIKQGENPLQLDSRTPKLPLEQYMYLENRFKMLTKSNEEAAQQLLKEAQADVKTRWQMYQYLAARNY
>NZ_CP046703|553986:640842|631674_632391_-|WP_114084459.1|DBSCAN-SWA
MSVKTLTVNDKLISAREEETILQAVQDAGIHIPTLCHLQGVEDVGACRLCLVEIAGSNKLQPACVTKVAEGMEVQTNSDRLQKYRRTIIEMLFAEGNHICSVCVANGNCELQDLAIEMGMDHVRLDYHFPDRKVDISHARFGVDHNRCVLCTRCIRVCDEIEGAHTWDMAGRGTNSHVITDLNQPWGTSNTCTSCGKCVNACPTGALFDKGSSVGEMKHDRAKLDFLLTAREKQQWLV
>NZ_CP046703|553986:640842|638467_639040_-|WP_159402435.1|transposase|DBSCAN-SWA
MQKLRAEYWTIIGEVNLADLVFIDEAGVNIAMTRRFARSPQGSRAYGHCPDGRGKNVTMIGAMSTEGIIAAMTFTGGTNASAFETYVTQVLVPSMKPGATVVMDNFSSHKVTGIREAIESVGAKLVYLSPYSPDFSPIENCWSKVKEFLRSQAARTYQELDEAITNALNAVTKKDIIGWFTHCCYYIAPN
>NZ_CP046703|553986:640842|581477_581828_-|WP_114084431.1|DBSCAN-SWA
MTTSILSLKITKIRWADIIEYPQHGAKSKVLLEDGNCRYTLISLAAESTIAEHTNPRNATVNVIEGQGVLTLEDQEIVLESGVFAFIPANARHALKAATNLAFLLTLSEQVANSKH
>NZ_CP046703|553986:640842|601382_601961_+|WP_114084439.1|DBSCAN-SWA
MVEKQRGVTIWLTGLSGAGKTTICRYLDTKLRSQEYKIEVLDGDVVRQNLSKGLTFSKEDRTENIRRIGFVAHLLTRNNIIVLVSVISPYRVIREEVKAQIGDFIEVYVNAPLEVCEQRDVKGLYKKARFGEITNFTGIDDLYEIPLKPDVECKTDQESIAESANKILNKLEELGYINPLLLPQLHNNYSRI
>NZ_CP046703|553986:640842|576891_577569_+|WP_114084428.1|DBSCAN-SWA
MVHSIDRRNFSTNRATPSRIDELSRNASFVSNELPGDHTVSVAYLNSLTGTPNTLVSNNAPSTDGSLIDRALNFVSQTSAAFGFAPSEPVEFVPDPTIETTSADSRAVHLQQTYRGIPVFQMVRTVRFSPNQEINEVVGNNVNLPTGINIAPQIDVTQAVTSAAAYIANPNETEEMRDGWGQPITPISVDLSDYNPRVLVTFPMPSQPTVLDQDLRNWHSAIAIL
>NZ_CP046703|553986:640842|601990_603160_+|WP_114084462.1|DBSCAN-SWA
MKYRRFGRTELLMPVFSCGGMRYIYTEYEELTQEKIPDENQQNLEATIRHSLEVGINHIETARMYGTSEMQLGAILPKFPREKIIVQTKVAPTSDSEDFRRLFEKSLALLKLDYIDLLTLHGINYDQQFEDSIRPNGCLDVARQLQAEGKVKFIGFSTHAPTDLIIKTIETNQFDYVNLHWYYINQFNWPAIEAATRHDMGVFIISPSDKGGMLYKPPQKLLDLCYPLSPMMFNDLFCLSHPQVHTLSLGASRPSDFDEHLKVIELLDKADEILPPILNRLEKAAIATLGKDWYCNWHIGLPRYPQTPGEINIPVILWLRNLAIAFDMWEYATRRYNHLNNADPWFPGVTAERVRQFDLGDCLRHSPYADKIPALLEDAHRLLAKPSQE
>NZ_CP046703|553986:640842|607650_608145_+|WP_114084443.1|DBSCAN-SWA
MKQYLEYFNIIFLIDKVYFYLHSALFSRFIRFAVVGLSGVFVDLGAFYFLHSSLCLALTMSAMLSTEIAIINNFLWNDLWTFGDVSFQQKISQKLQRFVKFNLICLVGLIFNSLIVNWLFYQFQVNEYIAKLVAIACVTLWNFWLNLKMNWQLTKTEVDVVVDI
>NZ_CP046703|553986:640842|635428_636478_+|WP_114080505.1|DBSCAN-SWA
MARKKSSPLQSTEVTPLALSQLHIRLEFLEAEHKSLLKQIKRKRTELNNFVEQMRTFATEIFHQASPHVQKMAELDRDIHALFDEIFTTRKFGKQTIKNIEAVYLELQLTGIISPNANRKQFNTELNELFNNSESESDFSEEAAEDSHQYWQAQQSVESPSVARTEDKRKIRETFLRLAEIFHPDKTRDSETQIYHTEIMKSINKAYQEGDLARLLEIERIQQVGEVIDLNNEDDLTRKCRTIEQQNQILVTQYENLKLELRLVKNTPEGTMVSDSRKAAKKGIDSMSLMLKTIESQINVISQIRDFVKDFREQKITIKEFLGGPPTPHSLDEEIMEDILEQMLSELMR
>NZ_CP046703|553986:640842|605952_607596_+|WP_114084442.1|DBSCAN-SWA
MDKLQLLAKSKPPTWLKILVISLMGLGIFFRFTHLGQKVYWYDEFATSLAISGHTLAEVKQEVFSNWSNDGGVIPVITLDKYQHINPDRTVADTVRYLITSDPQHPPLYYVMVRLWAQVFGDFPAAVRSLSAVISLLIFPSVYWLCLELFESPLVGWVGMAVMGISPLQIFFAQDAREYGLWMVTILVSSAALLRAIRQESSLSWAVYALTLALGFYTHLLTAMVAIAHGIYIVIRQQFRFNKTLRNYLLSSIVASLMFLPWLMVIITQIHTATNLLSWIKFKTDSPFDLIGIWLSRISRIFFDFNLASDDAWVNNLPAESPLTYSIPTIIASLFLIIYIIIFFIKYLSTNASLFISLLGGFPGLTLLFYDLIFGGIRSIHFRYQLPLYISIQIAVVYILSFHLLLAKNWQKNFWKVIVVGLLISGLVSDIRFFQSETWWPQIGAKNLLAMSQLINQSNNNILLVSSKNDYNLGVILTLSHNLEPKVRLLTIQNDQLPIIPQDYKSIFFVDDLENSLAHQLQQDKTNSLKLVYPLEGFWQLDKNQKT
>NZ_CP046703|553986:640842|610913_611888_+|WP_114084446.1|DBSCAN-SWA
MTTIYLHIGMPKTGTTCLQKALFNNRNKLLENGYLYPGSGIKYNAKEIVNRYCHNTLAHYLMGFENKDNALSQFTVWEELKREIDSINPKNVIISAEAFTSFEIFYQPETLAKIKNFLKEYKIKIVIYLRKQDEFLESSYCYMVKLGACSVGIKELFNEYQYIFNYYQILDNWADIFGYENIIVRRFEKSNMKTHIFDDFLGVINQFDNKSDYQIDYAAKINVSPSGKTIKMLLLINKFNETTLARFLKLDDNYWSKYQDFLDFLSNNKTINKFVSKLPNFLVDNVLLSSEEKQDFMRQFKELNSQVANKYLGQKDGILFGDYS
>NZ_CP046703|553986:640842|584922_589212_+|WP_114084434.1|DBSCAN-SWA
MNFLEEDSLFLKKIQQLKTKLELVLLEKAPLKECTVIVNKTYPLEVVTYIVSSSNNSLKQICSYLQNVSGEALLPKAIVPVSYIPLTATGEVDELALMNIPIVDESLIEQVEKQLNSHHKIEQAVVVVQELRKNIPSLHLSDLIPDWQDKNAIAGGGVLPIANVVPIPIGSQANTQQHFSEPKPLAISHGGILPDDPNAPITLPEVLQTAAQQVKSAGIIYLLPDGTELRQSYAELLEVAERILAGLRKLGLKPKNKVILQMELSRDIIPAFWGCILGGFVPVIMEVPPTYRESNKVVDKLCHIWQFLDSPVILTTEALKPEIEFLSEWLPVERIKIGTIEVLKNNTASKQYHHSQPDEVALFNLTSGSTGIPKCVQLTHQNLIARAKGANLLNQHESEDVILNWLPFDHIGSISDWHIRGVELGCTLVYAQKEYILGRILNWLDLINKYQVTHSWAPNFAYAIVNDSLKQEPEQNWNLSFVKFLLTAGEAVSSKAVEDFRENLVVYGLKATAIRPAFGMAEMGSGITYYQPLQEAPLLFHRVDKSILQGTIKRVETDHPNYSTFTDLGSVIPGITIRIVDEQNSVLREDTIGRLQVKGDAVSPGYYNNHNANNQSFLKDGWFDTGDLGFITNGQLVVTGRAKETIIINGANYYSHEIEAVVEEIAEIEVSYTAACAVCNADDATEKLAIFFSSPITEEAKLLELLKKIRQTVVNKIGLNPDYLILLAKEDIPKTVIGKIQRSQLSDRFHAGEFNPILKRLDILLGNTNTIPDWFYQKVWRPKQAKALKTLSSNFITIVFLDELGLGTFICQQLEQQNLPCLCVSPGSYFAKKSPNHFFLAPGNADHYQLLLDTIKADNLTIGQILHLWNYQEYQGEIKSIEALEKAQSQGIYSLLFLTQALAKTQNFQDLVQLLFVSSYTQSTQPTDKIAYEKSPVLGVIKTIPQEIPWLNCRHIDLTPNLIQVNANYLLQELQVLSKEQEVAYRNGQRLIAGLEKVYLEDKPKQKLPFKSGGMYLISGGLGGVVVEIAKYLIKFFNAKLLLVGRTHLPNENITSNVSTEILEKVKLYQELKQLGSVVYEAVDICDLQALQQVVEKVKANWGSQLDGVIHLAGTYQEQMLVDETPQSLAAILRPKVLGAWVLHQVLEKQGQGVFISFSSLASFFGGATISAYAAANNFLESFNQYQRSIGGLHNYCFAWTIWHDTGINKGYQRQEITHAQGFYEMSLQQGLYSFLAGLYHDQPQLIVGLDGSNAKIRRFTSEFPGLQKLTAYFTTSNGSAVPELSDFTVRDRFTTTVNCDFVQLSQMPLTASGEINRELLARGMTSIGAIAPRNETERQIAQTWQEVLGIPQIGIHDNFFELGGNSLLAFQVISRLRETFSVELSPNRFFASPTVAGLGESLEALQTVVTKWNAAMDDAEKEYEGGVL
>NZ_CP046703|553986:640842|565675_567304_-|WP_114084422.1|DBSCAN-SWA
MAEIDIAIVGGGVSGVYNAWRLKQAYPDQNIVVFEGSNYIGGRLLSVRPPDISNMVAELGGMRILPTVQPLIAKLIGELNKVLPLEQQIELYDFPVDQPQNIAYLRGVYLRLSDFTIKPDKVPYHLSFLERGGTAGSIIINAIEQIVPGITNPKLTESQRREMAQNASFAGTPLWKQGFWNVLIRIISGEAYELGIDAGGYNSTLTNWNAADAIPWYLSDFGIDPQYKGFKKGFQEVPKSLAQLFSKAGGEIRLNTRLDGFDWKNGTFELSIEGETIATKSLILAMPRRSLDLLVPTSPPMLEIQHLITSVTPRPLFKLFTTYTNPWWRAAGYTDDGKFIPVESGRTVTDLPVRQTYYWPKDDGKPATEGLSMLMASYDDGTDIGFWDGLRPRRHQAWQAHRQVAELVKNPYLGSSKQKLNSEWDKYVAPAPMVEEVARQLGIIHGLNYTPDVQNAAFRDWGDDPFGGGWNSWNIGVKSWEVKQQIIQPLGTDCSLYICGEAYSDAQGWVEGALQTSDMVLEKFGISPLLSSTVQRKKQTIK
>NZ_CP046703|553986:640842|623837_624293_-|WP_114084464.1|protease|DBSCAN-SWA
MSTTGYAYAIGYGNELRSDDGIGQRVAKALHLSNVKSLAVHQLTPELAEALAHADLAIFIDACFTSESSQVQVQSLSSESFNIIAGHTADPRSLLALTQALYNRCPQAWWIKVPGVNFELGYSLSPFAEIGVAIALQKITQIIDENFSLLL
>NZ_CP046703|553986:640842|620998_623806_-|WP_114084450.1|DBSCAN-SWA
MQKPIQSSSNRAYDILRTEKANPLDAIFVPKSVAVIGASEKAGSVGRTLLWNLISNPFGGTVFPVNPKRHSILGIKAYPNIFDVPEKVDLAVIATPATTVPGIIAECVDAGIKGAIILSAGFKEAGAEGVALEQQILEQAQRGKMRIIGPNCLGVMSPRTGLNATFASTMARPGNVGFISQSGALCTAILDWSFRENVGFSAFVSLGSMLDVGWGDLIYYLGDDPHTKSIVIYMESIGNARSFLSAAREVALTKPIIVIKAGRTEAAAKAAASHTGALTGSDEVLDAAFRRCGVLRVNSISDLFDMAEVLAKQPRPQGPRLTILTNAGGPGVLAIDALIAAGGEVAPISEETSASLNQLLPAHWSHGNPIDILGDADPQRYTKALEIAAKDPNSDGLLVILTPQAMTDPTQTAEQLKPYAQIAGKPILASWMGGADIAAGEMILNRNHIPTYPYPDTAARIFSYMWQSSYNLRGIYETPIMPALDSSSGIPDRNCVEKIIQSARQTQRTILTEFESKQILAAYGIPVVATCVSKSEDEAVQCAEKIGYPVVLKLFSEIITHKTDVGGVQLNLRDAEAVRQAYRNIKSSLQDKLQHDPHYSALSTQYSALFLGVTVQPMVKMAGYELIIGSSLDAQFGPVLLFGTGGQLVEVFHDRAIALPPLNTTLVRRMMEQTQIYKALKGVRGRKSVDMAALEQLMVVFSQLVVEQRWIKEIDINPLLASSEQLIALDARIILHEPDVKKDQLPKLAIRPYPTQYVSKWTMKDGTPVTIRPIRPEDEPLMVQFHKTLSEQSVYFRYFHLIKLQSRVAHERLTRICFIDYDREIALVVEYQNPETQTRQILAVGRLSKIHGTNEAEFAIVVCDRYQCQGIGTELLQRLLQVSRDEQLSTITADILVDNYGMQKVCEKLGFRIQHTDDPTVLKTEIDIKTFHPKN
>NZ_CP046703|553986:640842|639581_640103_-|WP_159402436.1|DBSCAN-SWA
MRVPRPSREQQALQLAEQSRARRVAIHQQVWDLHDQGWSGKAIARQVGIGVTSVFRYLRTPTFVEPTRRRSRGRSILVPYQEYILKRWNEGCHEGLVLFEEIQQQGYKGSYDTVARYTRRIRTALGIKPRKLYSVKSLPKVTQPKKLCLTPRRAVWLVLRKPESQLPEVSFES
>NZ_CP046703|553986:640842|594193_594790_+|WP_147262558.1|DBSCAN-SWA
MLEFQIEFQPRIPPSKNLVIGTLGPNATSSDYAAKHITNHLLSEQFTVSTQLFDTFIDVKEALLQDKVDMALVPHAYDRINEFYMEPSFDLGFIFIFPTPVYGLAKKKNKEVVFNGSRIVTHPAPLPLLTKLLPDSQDQTQIQVDLSPSTSDSAMQVMQGLADFAITNENAVKAYDLEFISIYGNIRMSWSIFQKKLN
>NZ_CP046703|553986:640842|589212_594051_+|WP_114084435.1|DBSCAN-SWA
MTIIEFVSYLNSLGIKIWLEGGQLNYRAPKGVMNPDLKNKLLGRKSEILAFLEEAQIATDSSFEPIPSIERSEELPLSFAQQRMWFLYQLESQSPFYNEGLQLRVAGVLNVEALQQSINEIICRHEILRTTFPAVDGKPLQIISPSLTINIPVLDLQGLEESEVQQIVTKEARQPFDLSNGPLLRVTLLRLGSESHVLVLIMHHIITDGWSMGIFIQELSTLYRGFTLNSPLLLAELPIQYADFAVWQRQWLTEEIQKQQLNYWKQQLADAPPLLELPTDKPRPAVQTFCGATQEFQIDQNLSKQIKTFSQQSGATLFHTLLAAFVVLMFRYSGQDDICIGSPIANRNRREIESLIGFFVNTLVLRNQIKGNPSFNEFLSQVRQVATSAYTHQDVPFEQVVEALQPERSLSYNPLFQVVFVLENFLLDTLELPDVTLTPQFVERGTSQFDLTLAVWETKAGLIGSWEYNSDLFEPDTIARMTSHFQTLLAAIIANPNQSIGELPLLSQQERHQLLVEWNDTYTPYPKSKCIHELFEEQVEKTPNAIAVVYENESLTYQQLNDRANQLAHYLQTLGVGAEILVGICIERSSKTLPKASLLMVVGLLGILKAGGAYLPLDPAYPQERLAFMLEDAQVSVLLTLESLVTTLPPHQAQVVCLDSVTFSARTENLLHTVTTDNLAYVIYTSGSTGRPKGVQIEHRGLLNLVFWHQQAFAVSSLDRVTQVAGVAFDACGWEIWPYLTAGASIHFPDDETRLYPEQMRDWLLSKAITISFLPTPMAEKVLSLNWPANAALRTLLTGGDQLHQYPSTSHPFEVVNNYGPTENTVVATSGTVPKRQQAYLPPAIGRAIANTQVYVLDSLLQPVPIGVIGELHIGGESLARGYLHRPDLTAERFIRNPFNRSRGHTSTALSNQGVGGKGETENCDRLYKTGDLVRYQADGNIEFLGRIDHQVKIRGFRIELSEIEAILTQHPQVRDAVAIAREDIPGVKSLAAYIIPELTQPTSNELRLFLKSKLPSYMVPASFTILEVLPITPNGKVDRRALPVPEFESDESTGFVSPHTQTQEVLAKIWRDILVLKQVGIHDNFFELGGDSIISMQIIAKANQAGLKLTPKQLFQHQTIAELAPVAGIISSVQSEQGLVTGIVPLTPILHWFFEQNLPEPHHFNQSFLLEVPANLQPELLEQALQKLLSHHDALRLRFVQQEGQWQQYNSDASDEVSLGITDLSYLPPAEWLKAIEAKADETQSTLNLADGPLMRVVLFHLGNSPARLLIVIHHLAVDGISWRILLEDLSEAYKQLEVGKTIQLPTKTTSFKDWAIRLQDYARSQELHSQLNYWLDSMRFPIAPLPLDYAAIAQDNTVASSRIVSVYLSVEQTRALLHDVPGAYNTQINDVLLTALVQTFTRWTSSYSLLIDLEGHGREDLFEDVDLSRTVGWFTSIFPVLLKLEDRNDPGKVLKSVKEQLRRIPNRGIGYGIWRYLSLDESDRNQLQVFPKAEVSFNYLGQFDQTQLATLGWKYAQESSGSIHSPKGQRRHLLTVNGLVVEGRLKLEWQYSEHFHSWATVENLANEYIETLETIIAHCLTPEAGGYTPSDFPEVEFSQEALDELLAEIN
>NZ_CP046703|553986:640842|626165_626921_-|WP_114084453.1|DBSCAN-SWA
MNQSNNSGILEQFVNTVMGVKAGNQQQYRDTSIATTQELDVRAILVYTLGTILQIVVMILVLLGMEKIVMLIDSNSSFPSWFSTLLTGLFFALLSIRSRIFSLLDNTRSRQTYDQVIRPRWSPPPLVFPIVWMIIAVLRVISSVLVWQQMNHQFLVLPLILFVVHLALGDTWNTIFTVERRLGAAVPVVILGPWLSAVVVTAIYWQTNPVAGMTLSFSCVWLTVAAVLVFRIWQLNGSEPLYPLKLKPLEK
>NZ_CP046703|553986:640842|616991_618365_+|WP_114084448.1|DBSCAN-SWA
MEKTRLTVLREMRLFIIVWVGQLIALIGSSTTAFALDIWVYNRTGSVTQFALVSLFNTLPLILISPIAGPLVDKWDRRKTMIIADVLACLGTIAIGVLFVIGRLEVWHIYLANTFTAVFMAFHTPAYTASTVLLVPKQHLNRANGLMSLMFGISLIVAPTLGGVLLSIVHLQGIILFHVSAVFIAVVSLMLVRFPEVNTSAVATAKSSFLSEATYGLTYLIARPGLLGLVLFSASSFYIVGGINVITIPLVLNFVSVSFLGTILSLFGIAIVAGGLLVSIWGGLERNIYAIYGCMLLSGVFIFVAGLQPSLVIFTVGIFLFFLTQPIVSSSTQAVMQNKVEPNVQGRVFAIKGAIEAAAFPLGYITIGPLAEKVFEPLMATNGFLAGSIGQIIGVGSGRGMGLLLMIMGVLTILETSIAYLYPRLRFVEDELPNVSNAVAMAADTASSKNDAVSLIS
>NZ_CP046703|553986:640842|618594_620607_+|WP_114084449.1|DBSCAN-SWA
MQTKVSRGQSLKNDPSPPASNNFWENVRAIVQPYWYPTESGERVFPDVIRIWGMLILLILLIIALVGVTAFNSFVTRYITDVIEEKDYPNFINTIVVFGAALVCITLLNGFSKLVRKKIALDWYKWLNNHILSKYLSNRSYYKINFRADVDNPDQRISQEIEPITSNALTFSATFLEKVLEMITFLVILWSISQFIAIVLVVYTIVGNLIAIYLGQQLNKINQEELELKAEYSYSLTHVRNHAESIAFFQGEKQEFNIIQRRFINLLKNVERKINWENNQELFDGAYKSAIQIFPYLVLAPLYMSGQADFGEVVQASVACNQFASAMATLIREFGTSGRFSSYVERLSEFSDALEAVTKQPENVSTIKTIEENRLAFENVTLQTPNYEQVIVENLSLSVQPGEGLLIVGPSGRGKSSLLRAIAGLWNAGTGRLVRPPLKEVLFLPQRPYIILGTLREQLLYPNTNRQMTDAELKDVLQQVNLQNLLSRVEGFDTEVPWENILSIGEQQRLAFARLLVTHPSFTILDEATSALDLKNEGSLYQQLQSTKTTFISVGHRESLFDYHQWVLELAQDSSWQLVTVQDYRNQKASITKFPSNTQIKINDSPEDKAQNESKISTGEKLTHKAMNELTSYSLSTIRSKASKGEFITTKDGIIYRYDKDPNVLKWVLV
>NZ_CP046703|553986:640842|574447_574762_+|WP_114084429.1|DBSCAN-SWA
MKVKFVQSGGYAGLRRGCEVDTNLLPSNEGAKLKSLVEQSGILQKAKSNHAPHARDLFNYNITVETAEGEKCNVSFDDLSLPEGIQPLLNYLQNCAYPLTPNVN
>NZ_CP046703|553986:640842|583086_583767_+|WP_114084432.1|DBSCAN-SWA
MSKLILITGISKGLGYAMTEGFIQQGHTVIGCARSSDEIDKIRQKFSAPNDFTSVDVANEQLVKKWALDVLQKYEPPDILINNAAITNYPAPLWEIPSEEFSDLIDINIKGVANIIRHFVPAMVKKKRGIIVNFSSGWGRSTSAQVAPYCASKWAIEGLTRSLAQELPTGMAAIPLNPGIIHTDMLSISFGEEAANYTPVSDWVLKAVPFILNLKPKDNGIPLTIH
>NZ_CP046703|553986:640842|553986_554400_-|WP_114084414.1|transposase|DBSCAN-SWA
MKDDFVSKGRSISDMKVHLVLVTKYRRKAFTSEMLSKLNTVMQELLEKWDCKLVEFNGEDDHVHLLFQYHPDVELSKLVNILKSVSSRKLRQEFAEHLESFYWKDVFWSGSYFVASCGGVTVSTLRKYIEAQESPAE
>NZ_CP046703|553986:640842|563319_564726_-|WP_114084420.1|DBSCAN-SWA
MTNEKTLTQLNFSDIQGYIIRGYNMNNVRHFVLYIKDAKGAKKFIGSLVSGSDESIPQITTAAWWDIKPSYCLNIGFTFEGLNALQFVADIGKSFSGSNYKSFRQGAIAQATQVGDIGESVPEKWKGGLGTSNTHVLLSLYAQDSKVLEQQSDKLRSLFKEGDALKELSCFDGAKLPDEKGQPSDIVHFGYKDGISQPKIEGVPTKRGLSKSLDPQPIIPAYEFILLDDEKAPYYVPTPPELGLNGSFAAFRVLEQDVAGFEKFLQEQKDKIDSDKLAAKMCGRWRNGVPLDLSPDADQLTSPKESIIYEQFNNFDYSDDPQGYKCPIGSHIRRTNPRAAKIQGVTNIHRLIRRGIPYGSLYNPNSPNDGIERGLLGLFICVNLKRQFEFVMEEWVNKGDFAGLPTDVKAPLIGANDNKSGQFDIPVSPDNPSIKLTGFDRFITTKGGAYCFIPSITALQHIASHSTK
>NZ_CP046703|553986:640842|631113_631638_-|WP_114084458.1|DBSCAN-SWA
MLRRILKIFWWLLLLAILTIYIYLGLASFTSQQVIAAVMQLEDTPEEILYRSQEKLNDELGNYWQVILFKRVNSNSNKISSINLRLVGFPGSQELPHPLPLKITTDTGKVLTAPDIFLDEAPAPTIAQYDLKDVLPQLSTQELLIGIPVGKQHFINISIPKYVVQEWQEIALKS
>NZ_CP046703|553986:640842|555680_556712_-|WP_114084416.1|DBSCAN-SWA
MDLTTTYMGMKLRSPFVPSASPLSEDIDNIQRMEDAGAAAVVMHSLFEEQLRLERDELHHHLTQGTESFSEALSYFPNSASFRVGPETYLEHIHKTKQKVSIPIIASLNGSSVGGWTNYAKQIQQAGADALELNIYYVPTDMELTSNEIEQTYINILCAVKAAVTIPVAVKLSPYFTNMANMAKRLDEAGADALVLFNRFYQPDINLNLLDVEPNVLLSTPQSMRLPLRWIAILYGRIHADLAATSGIQRGDDALKMLMAGAKITMLCSALLRNGINHIRVIEQEMREWMQKHEYESVQQMQGSMSQKHCPNPSAFERAQYMRSLATYKPEWATIHDTSYYFG
>NZ_CP046703|553986:640842|554453_555641_+|WP_114084415.1|transposase|DBSCAN-SWA
MRISYQYRLKPTKEQALHIDKTLDMLRCQYNYQLAQRFDWYEQNRCPIDRCSLVLCHIPELKDKPNRFSQQATLTQLKKDRPWYKSIHSQVLQEVPKKVELAFDRWLKGDNTGNRSGKPRLKGKGQYKTFTYPQFKKEHFENDKITLSKIGAVKVIVHRQMPEGFDIKTVAVTKKADGYYVTLSLEDKTVPTVKPDFDTNNIVGIDVGLIDFYVASDNTRIAAPKYLRKAERKLKSAQRRVSRRKKGSNRRKKAIRKLGIQHKKVADTRKDFHFKAANNLLKKYDVIAVEKLNIKGLAKSRLAKSVNDAGWGQFISILTVKAENAGLKVVAVNPNGTSQECSNCGTKVIKPLSERTHNCPNCKVSLCRDLNASLNIKARGAHALKAQIMSSLKSL
>NZ_CP046703|553986:640842|629615_630254_-|WP_114084456.1|DBSCAN-SWA
MLKASDIMTRDVATIHSSATVAEAVRLLRARDWKALVVDRRHEHDAYGMITEKDIVYKVIAYGKDPFSVRVHEVMTKPCIVVNPELALEYVARLFADHNLQRAPVIQGELLGIISLVDILANSSFLEQPHTFLLEQQLQDEIQKARVICDRQGIHSEECAVVWDAIEELQAEIAHQRAEKVVKTAFEEYCDEYPEAKGIYDNWSSSLPTQKC
>NZ_CP046703|553986:640842|603179_604979_+|WP_114084440.1|DBSCAN-SWA
MSYYKLLKNNKKYTLIRHRWLVILLALITAIAIIISNQINLKNQATAISQVIVSFPIEPTTFNPALIVESAYTLNYTYEGLVKENGRGEIEPSLAESWQTSPDKKQVIYTLRKGLKWSDGKPLTAEDVVFTYNEIYTNPAIPTYAKDFFIIGKNRTFPTVRKLDDLRVEFRLPEPFAPFIRATKLEILPAHIFRESVKIKDQEGRPKFMSTWGIDTPPKNIIVNGPYTIESYTPSQRIIFRKNPYYWRKDAQGNSQPYIERVIGEIIPSQDTSLIQFRSGGLDYVSVNTNYFSLLKHEEGKGKFTIYNGGLFIGSTAITFNLNKGSRNGQPLVDPIKSRWFNTVEFRQAIAYVINRQQILNNIYKGLGQLQNSPIAVQSKYYLPVQAGLKVYEYNLQKAKGLLLKAGFKYNNQGQLLDEQGNLVRFSLMTNANNNILQAMGVLIKQNLSDLGITVDFNPVATSIFINKLTQTFDWECQVLEVAVGQEPNDWANVWLPETGWHFFNQKSQAGQTPIAGRQVADWEQKIGDLYIQAASEVDEAKRKAIYAETQQITQEYLPFIYLVNPLSMVAVRNRIQGIQHSALIGTFWNSYDLKLTED
>NZ_CP046703|553986:640842|565088_565541_-|WP_114084421.1|DBSCAN-SWA
MSTKPEQSPLSFVAPIKAPVLENYKALKDILETGTFGTALDQIGTVHFGRFMFLEKVTPESGEEYYAKFALFTAYDGDFNKYVDDFVAVVGDFFNAVLVHLENAEGLIPVQKDSEAFADYIKKYNQPVKVWYSAYPTLSVVKIRQLASNC
>NZ_CP046703|553986:640842|578855_580712_+|WP_114084430.1|DBSCAN-SWA
MQLSELSLFQTFRRSLQLVIQSATTELRTLIFLTLISGSSPAISLFLNKIIIDQISHLLGKYTTVSSLILILQEPILLGSIGGLILLNLLTESMNAIASLVFSSLRDRVQGFAQSIVLNKVANFADIALFETPELLNLVQLAETGIERLKELSLLVITTLHGFFILIPAILLSGSITWWIPLILFTSATPAIYVELTYRKKSWEVEETQASLVRQMNLHRDVLVGEAYAKELRLFQLQPLLLDRWQNLFQTMFRSMQQIRKKGMVLVITWSMVNGLGTALPYIYVVIGALRGIYTLGDLALYAGLILQVRQSLFLLINNGSNLYDVVLGTRPILQLLELKPKLRLSLASREDTAAKLSLTPRVIAQHQGIQIKNLSFSYPGSDSKILDNINLTIQPHQTIALVGENGAGKTTLAKLLCRLYDPGSGEILWNGQDLREIDLVQLYSRLAVVMQDYARFPATVCENVGFGYLSALQDVNAIKEALRAAGIAKVVDNLPQGLETLLGKQLADGVDLSGGQWQRIAIARALMRLSSAELLILDEPTSALDPKTEHEIYQLLRTIAANKMAVFISHRLALSKLADQIIVLENGKIIETGSHEELIVRGGQYHLMFSRQASSYQ
>NZ_CP046703|553986:640842|561025_561217_-|WP_159402433.1|DBSCAN-SWA
MKVNRKNSYSPSNRFKYLAKSLCVFILTLCFAIAVFPTSAQARVMQYQKSNPADVNPLSILFG
>NZ_CP046703|553986:640842|571587_571806_+|WP_114084425.1|DBSCAN-SWA
MRLIPAFLTSAAMATPAAGIALFIILTQNMFRALLTVYFLMQCEKPKSRFYKALRILVRNTAMFRYKRLVYE
>NZ_CP046703|553986:640842|583777_584209_-|WP_114084433.1|DBSCAN-SWA
MNIDRLQSLKQKLTNDADLSDIWLFYMDHFADWPEFTDLGEPAHNEYLDAVLQKTCQQMFSRAINISDFLLIYIAPYHLFHGAFQIEGRIGGVIYFEDIKIGLLAVSADYPPTDAVKYSRFTEMIQLSAPNGNDVYDGLRLRN
>NZ_CP046703|553986:640842|577701_578715_+|WP_159402434.1|transposase|DBSCAN-SWA
MRFTKLNYCQYLLSSQINYTLTNLAEHLEQISHDKINRYLKNEKLTPRLLWDNVKDILQVSDSAYLVFDDTVLDKRYATEIETSKRQYSGNQHGVIQGIGLINCIYVNHEIGKFWIVDYRIYDPDRDGKKKIDHVTEMLQNLIYHKALPFQAVLMDTWYATNKLMLYIDGLGKYYYCPLKRNRLVDDTAGQKNYQRIELLSWDSQELKSGKIIKIKKFPQATKVKLFRVTVSTDRTDFIATNDLSQDSTDVVQKVCKVRWKVEEFHRELKQVTGIESCQCRKGRIQRNHIACAILVWLRLKHLAYQSYQTIYQIKHGLLSNYLVQQLKRPNVPMFIV
>NZ_CP046703|553986:640842|630325_630871_-|WP_114084457.1|DBSCAN-SWA
MTRLKLATVWLGGCSGCHMSFLDLDEWLIDLAAQVDLVYSPFADAKEYPPGVDVVLVEGAIANEDHLQMIQIVRERSHILVSFGDCAVTGNVTALRNPLGSAEPVLQRCYIEAADIHGTIPYEPGIVPTLLDRVIPVHTVVPVDIYLPGCPPSATQIKAVLEALLRGEKPRLKGREFIKFG
>NZ_CP046703|553986:640842|594799_595498_+|WP_114084436.1|DBSCAN-SWA
MSKYFPQPKTIKINSDVELIAFQCQDTVVQLASIPPGATFELHRHPESQIGMQIAGRLEFNLNGTKEILEPFGQVYVAGSNVLHGSKNPFSETALAFDVKRITNSEEAEEAILKVSPTQDEITGFECQSVAGSWFEIVITKIPPKGIIPIRQFGNETMGIVLNARLTIAVEEQQQNLKYGSVYYAPANALYGGHNPSDETVSVIEVLIKPRSNFSFKDAFLKTDVVRSLTTS
>NZ_CP046703|553986:640842|569288_571196_-|WP_114084424.1|DBSCAN-SWA
MDLPQPLESPYGFWKSLITADAIVAETINIQEVALDGKDVYWIESRPSEKGRYVIVRRTANGEIVDITPKGFSARTLVHEYGGGAFVVKDGVTYFSNFNDQRIYRQTNIDTPQPLTPDEKKRYADGDYDVARNRIICIQEDHTNELCEPVNSIVAVADSRKLESLVQGNDFYSSPRLTHDGKQIAWLTWNHPNMPWVATELWIANCTDEGKLENSQKVAGGSAESILQPKWSPDGVLYFISDRSGYWNLYKFVNGKVEPVLLDEAEFGQPPWQFGTSTYAFVSANHIVCTYAKGGRWILGIIDLLTGLLKPIDTPFTYFTAVRATPGKVVAIAGSPTMTSALVQIDLKTYEVEILRRSTQENQQWQPYFSTSEAIEFPTEKELTAHAFFYPPKNPEYIAPAGSKPPLLVMCHGGPTAASDDTLNLSKQFWTSRGIAIVDVNYGGSTGFGREYRDRLKGKWGIIDIDDCINAAKYLIQKNLVDSQRIAITGGSAGGYTTLSALTFRNFFKTGASFYGVSDLELLVRDTHKFESHYLEWLIGPYPDRRDLYEERSPVHHADKLSSPLIFFQGNEDRIVPPNQTEKIVEALRGKNIPVGYFLFDGEQHGFRQAENIKRALEAELYFFDLWLTKSGLRF
>NZ_CP046703|553986:640842|616770_616950_+|WP_114084463.1|DBSCAN-SWA
MTLGTFRSPLALKKGGTGIKVPLKKGDLGGSKTFDTGNRTFQTSSKSREQGQQNKNRCN
>NZ_CP046703|553986:640842|604999_605929_+|WP_114084441.1|DBSCAN-SWA
MQIPIIDFNPFINGDTVAKEAVATQISLAIHEVGCFYLKNYGISKTLITQVFSQAECFFALPENEKEQVSFFPDRNLRGYHNFKKSEDNHNANELMTEGFHFGKEISLDEVGIIEDPFFEPNKWPHQTNFREMMMEFFTACHESALKVFQALAISLKLPEDYFTNLYSEQNHGIVWHHYPSIYQPPELGKVYLAEHTDIGTLTFLFQDSEGLEVYTNSGEWVLAPFIPDAIIVLVADLMQRWTNDKFCATRHRVVVPTQSHSAKQRYSCAFFTGPNYDTSINSIQTCLDIDEVPKYPPILAHEYFKQPK
>NZ_CP046703|553986:640842|612091_616735_+|WP_114084447.1|DBSCAN-SWA
MNKLQIIKNKNIESIYPLSPMQQGMLFHTLYEPESGVYLEQFCLMLSGNLDITVLQQACVRVMKRHPVLRTLVVWEKQEKPLQVVCKQVELPWQNYDWRSLSLAEQEERLKAFLQADRVQGFVLDKAPLMRFSLIQIADDIYEFVWSFHHLLIDGWSWPILCKEVFAFYNALLKGKYLYLNTPRPYRDYINWLQQQDLRAAEAFWRQQLHGFTSPTRLLLNRGEAHNLQQPKTYHEQHCCLSATITAALQSQAQQYHLTLSTFVQAAWALLLSRYTDESEVVFGATVSGRPPTLSGVESMVGLFINTLPVRVKVPTATPLWQWLRELQAQQVERSQYSWFPLVEIQALSEIPPELPLFESIVVFENYPHDPSLSNLGSTIQITKRRVIEQTNYPLTVIAVPGQELSLRILYDGSCFDAETINRMMGHLVTLLEGMSANVEQTVAEISMLTTTEQRQILVWNDTQKDYPQKCIAQLFEEQVERTPDAVAVSFQSQQLTYQQLNCQANQLAHHLQKLGVKPEVRVGICVERSLLMVVRLLAILKAGGAYVPLDPRSPQERLTYMLSDSQASMLLTDSSITLSEQPLTVVCLDTSDFCQNSQENPVNGVIPGNLAYVMYTSGSTGKPKGVAMSHRSLVNLLYWQMDEISLSCAKTLQFASISFDVSFQEIFSTWCNGGTLVLITEKLQKDGFALLQLIAQEKVERLFLPFVALQQLAHAASITQLYPASLRQIMTAGEQLHITPVLVNFFKELSGCTLQNQYGPTESHVVTSFTLKDVASSWSPLPPIGRAIANTQIYILDRHLQPLPIGVPGELYIGGVAIARSYINSPELTAEKFIAKNGNRLYKTGDRARYLSDGNIEFLGRIDNQVKVRGFRIELGEIETVLAAHPQVKEAVVIAREDEPGNKRLVAYIVPKQHLDTSELLCYLKQKLPEYMLPSAFVKLLDALPLTPSGKIERRALPAPLSRETRNISTDLIPPRTVTEEVLAGIWSDVLGLEKVGIHDNFFALGGHSLSAMQVIARLREIFKVELPISCLFDYPTVIELNRQISEYRQKEAGEQGSRGAGEQGRNNHSFSSPCAPLPSCKNDLTPFLKPVPRNTKELPISLTQLEFWILAQLHPGIPVYNIPLAYRLTGLLNVTALAQSLVEIVRRHEALRTTFAIADRQVVQKIAQQPILPFSVVDLRKLSESKTERKALAQKFITEEKNQPFDLEQEPLLRIKLLRLSDAEHLLIITIHHLVCDGWSVGVFLQELTKLYAAFCHGQPSPLPDLPIQYADFAHWQKQWVARPAFVSDLNYWKQQLSNSTLLLQLPTDRPRLPVRTFEGASQTFIIPKSLTNALKHLSQQHNVTLFVTLLTAFKIVLFYYTGQSDIIVGTPFANRQQVETKGLIGCFINTLPIRTHLGGDPSLSELLYQVRGSFLAASDRQQIPFVKLVEALQPKREPSHSLLYQVMFNFLPPSDLKLTNLTVHPWSIESKTAEFDWDIYLQQTTLGSIEGKWCYKIDLFDASTISRAVTQFLVLLELLITNPECRLTDLSLLFQRHNSQCRAM
>NZ_CP046703|553986:640842|574902_576798_+|WP_114084427.1|DBSCAN-SWA
MSENTHNVIFFDIGGTLGSPRISPFPYRLEGLDVYPYVPDILRQLRERNSRIGIISNIGDDKPENVKRVLEKCQIYDLFDSDLIIYGAKNSSEIFQFTARQAGHSDTPNQCLFVGEDSHERSYAIQAGWRVVPHPCLVWDVLNGSHLRYIRITVPSDRSEQGWQQVIKSLPVVPLYVTGDKGNQVYAIATSQAAMRLDDLGFAVDRLGSEDDPLTTEVYLLRDDLQKSTGFLNPQGRSTEFFANDESSKMVLASSTEGLFVALPSDRSVEDYHFENAQHGHNLKLLPDLSLLEPFGEGNNARTAGFLTSPTTEPSLNQAELDKFKAITPDKIRSHVERYAGIKPLNEQQRIIKSRHIHSPDMPLVTEALAQDLKSIGGDIFSVRMNPFVHEGRELYNVEAEIQGSQSQEIVLVTAHLDSTAASDRPYDAKNDPAPGADDDASGVAAVLGLAEVIKELNSFKPSKRTIRFVLFNAEEHGLVGSQAYARTQAAIAAPIVGVYQMDMIGYNIEAPRSFEVHVGYAKCDDVQRRSLVLAQRLERLVSVLSPRLEHPQIYTQPDPAEGRSDHASFHQRGYAACITSEDFFVGPDLTSPEAEPNVNYHRKEDKFVDFDYAADIARVVGAAAWVTANA
>NZ_CP046703|553986:640842|628043_629492_-|WP_114084455.1|DBSCAN-SWA
MKKVIINPVTRIEGHAKISIYLDDTGQVSDARFHVTEFRGFEKFCEGRPLWEMPGITARICGICPVSHLLASAKAGDRILAVTIPKAAEKLRRLMNLGQIIQSHALSFFHLSAPDLLLGMDSDPKKRNVFGLIAAEPELARGGIRLRQFGQEIIEQLGGRKIHPSWAVPGGVREPLSIEGRTHIQNRIPEARTIILDALGRFKDLLNDYQREVQTFGNFPSLFMGLVTPDGLWENYDGHIRFVDSAGNIIADKLDPTHYQEFIGEAVQPDSYLKSPYYRPLGYPDQSDHCRLDSGIYRVGPLARLNICSHIGTPLADTELREFRDRGQGTVTSSFFYHYARLIEILACIERIEIIIDDPDLMSKKLRADAGINQREGVGVSEAPRGTLFHHYQVDENGLLQKVNLVIATGQNNLAMNRTVAQIARHFIHGSEIAEGMLNRVEAGIRAFDPCLSCSTHAAGQMPLHIQLIGTDGNIVNEVWRD
>NZ_CP046703|553986:640842|596398_601348_+|WP_114084438.1|DBSCAN-SWA
MVVAQKQSKNKDIESIYPLSPTQEGMLFHTLYEPESTIYFEQFKLTIHGNLDPNIFERSWQLLVERHSALRTLFIWKNRKQSVQVVRKEVNLPWSNLDWRMFPQQEQEIRLNSFLDSDRKQGFELDKAPLMRFALIRVADETYEFVWSFHHLLVDGWSWPIIFKELFALYESIQNGQQLYLAPSRPFRDYINWLQQQDLAGAKAFWQQNLEGFTAPTPLIVERTIGQSSHQQQNIDVRSQHLSAETTTTLKSFAQQHHLTLATLVQAAWGLLLSRYSGESDVVFGTTVSGRPASLSGVESMVGLFINTLPARVKISDTTDLLSWLGLLQQEYIEREQYSYTPLVDIQGVSEVPRNQLLFESLVVFENYPVNVTLQQLPGNLNIGELQDRGQTNYPLTLLAIPGDEMTVKIYYDRDRFDADIIDHMAGHFLTLLEGITINPHRTPGELPLLTKAEQDLLLVEWNATSPAHPINRCIHQLFEEQVKKTPQALAVVYENQQLTYEELNQQANKIAHYLQRFGVKPDVPVGICVERSLAAAIAILGTLKAGGVCVPLDPTYPPERLAFMLNDSQTPVVLTQTRWKSLLDGNLAHRLIVLDEDGDEIAKESESNLQVEVAGDNLAYIIYTSGSTGTPKGTLVTQRSLTNLVEHHQAKMATGIGVLQFASLSFDVSYHEISVAWGFGGTLYIIPECDRKDLDKLIHLLANNPVGKVFLPVSLWQQLAEIYGEQEHLFQNIREAIACGEQLQITQPMIKLFKRLENCTLYNFYGPTEADLVTAYTFSQKPDEWPIYPPIGKAAVNVQVYLLDSNLQPVPIGVPGELYVSGDGLARGYLNRADLTNQKFLPNPFGRGRGAGGQGSRGAEILASPQSPIPNPQSPVPNPRLYKTGDLAQYLPDGNIEFLGRIDDLVKIRGFRVELGEVEAVLSKHPQINQAVAKVHGESAREKYLVAYFVPIVGETITVEQLRAFLTEQLPDYMIPSAFVEMESFPLTPNGKVNRRALPEPTTSRPELGQTFVEPRTPTEEILAGIWRDVLGLEQVGIYDNFFDLGGHSLLATQVIALTRKAFGIELPLLSLFESPAIAPLAQKIATAKAPDRQELSLKRFPPQNELIPISLTQLELWFFDQFYPGNSIYNLPLVYRITGALNEKALEESLREIVRRHETLRSTFQVKNGQVVYAVVNDPVFDFSVIDLQHLPETEREAQATQQAEQEIKHPFDLARGPLLRSKLWRLDEQEYLFVAVTHHIVADGWSFSVLTQELAKVYEAFCEGKSSPLTELPIKYTDFAQWQRQWLQGQVLESQLQFWKKHLGTNPPILKLPTDHLRPPARTFKSAGQPIILSQKLTDALKVLSQQEGVTLFMTLLAAFQTLLFSYTRQEEIVVSSALANRTRVETEGLIGFFVNLLPFCTNLGGNPSFRELLSRVREVALGVYAHQEMPLIKLIEELQPARDPSYTLINQVMFVFQNTPEDNLQFANLTLKEQFIARDTKDTAEFDLELTLEETSTGIDGLLVYRTDLFEAATITKMVDNFQTLLDKITSNYNQRLTELILISEHPSLPTPTIGSPISKDFVTPQNSIEEVVLAIWKEILGIEQISTQDNFFELGGHSAQTLEVICKLQSALQVKLPLFNLFEKPTIVQLAESIQSQLNSQNAF
>NZ_CP046703|553986:640842|595510_596305_+|WP_114084437.1|DBSCAN-SWA
MDLGLTQKVALVTGASAGIGYSVAQKLAAEGCQLIICGRNSERLEQAYQGLVSSQTKVIPICADVQNASDSQKLVQEALSQFGKIDILVNNSEGATFSNEAVENLSDEDWLSVFEGKLMGYIRMTNLVLPTMKNQQWGRIINIVGTSGKEPSSRLVKSGVANAGLINFTKTVATQVAKWNVLVTCVNPGLIDTPRHREYLEVFAQEEGRTVDSIIEGTNKMIPLGRRGVSSEVANLVAFLASECASYITGVTIPVDGGLSTSAF
>NZ_CP046703|553986:640842|640158_640842_-|WP_114080507.1|transposase|DBSCAN-SWA
MSVLTRLLPDSTNLKLESCLVDEIKTQIKLIVSAIITVVNCPVCNQPTHRIHSHYERKLADLPWADYSITLQLRVRKFFCINTLCNRRIFTERLNSVTAPWARRTLRLAQRLSAIALANGGAAGVRLSEQLGIKVSRNTLLNLVRSIPLPPIVTPHTLGVDDFCFRKCKTYGTALIDLERSRPIALLKDAKAETLAEWLKAHPGVKVVSRDRSLTLLLFISGFKEFY
>NZ_CP046703|553986:640842|627307_627646_+|WP_114084454.1|DBSCAN-SWA
MKKILLCCCAMILAMWVAINPALAADSKSPAPATDSNSTALAGDCTEVGFFPNEQDCTKFFRCVDFGDGRDLTKFDFDCGPGTVFDDRYDTCNHAWALPSDSTCYKPMESMK
>NZ_CP046703|553986:640842|632885_633536_-|WP_114084460.1|DBSCAN-SWA
MTPQDARQYAPATERNREPILEILLQVLPESGTILEIASGTGEHAVFFASRLSPRLWLPTDANLELRASISAWTEHNASDNVYPPLELDVREPVWAVEKGEVTEWLNREPIVAIVNINMIHISPWSACLGLMAGAGRILKAGGILYLYGPFKQGGEHTAASNAAFDEYLHTQNQEWGVRNLDDVVAEARAEHFILKQIYQMPANNLSVVFERAANE
>NZ_CP046703|553986:640842|561291_563235_-|WP_114084419.1|DBSCAN-SWA
MTFVDQNLATQRPKSLQDFSLPRRENYFPSPADWRNEVLYFLLPDRFSDGKEDTRPLLNRQQLNLARPSLPNGQSWQFDKWAESGGDRWQGGTLKGLESKLDYLNQLDITTIWVGPIFQQRGHLDSYHGYGIQDFLEVDPRFGTRQDLVSLVNKAHEKRLRIILDIIFNHSGSNWLYAPDTPGGELEPPYTSGWYQFGSWLGDRGQPIAVKPQTSAEGVWPRELQEADCYTRAGKGDLGRGDLDDPNAEFRRSDFITLRDFQLEYSYLLDNLARCYKYWIALTDCDGFRIDTLKHVTYEQARNFCGTIKEFAANLGKSDFFLVGEIAGGDYNQDRYLDVVGQNLNAALDIAEMRVNLNLVAKGLIDPRAYFNGFDPGKAVMGSHRNIGRRHVSILDDHDHVFGEKIRFSSEAASDHQVIAGVALQLFTLGVPCIYAGTEQALAGPEPSERRWLPDWKKSDRYLREAMFGPEHPRQSGVAGLQALDQNLPGFGPFGTAGAHCFEPNHPAYVRIKAMAAIRKQFPVLRLGRQYLRPIAIPFLNLPFGDHGRSGEIIGWSRVLDDEEAVCVLNSHGTDNRGARVLVDANLNAIESSMTVILNTAEMANLPGYTGPHKVGSTVLVQQQDGTAYVEIQPISASEFLILTNYP
>NZ_CP046703|553986:640842|608154_609291_+|WP_114084444.1|DBSCAN-SWA
MLKPLVMFGYSLIFIITIIFSSGFLNVILPYYKTIQNLGEISVKWQYLTEHKDDYDAIFLGPSTTYFGVIPKLFDEYLTTERKSIKSFNFGIAGANVSEVDFYLQKILELEPANLKWIFLDCSVDLFTNIGSTSAQEIYWHTPRKTLENFQLILESSIDSWKVKVPYIYANFQSFIYRWLGIGQLSTFWQEAILNLDLSNLDPLAKVSEDRLIQESGYYAIDWQEKAEKWKTIFRANGLDTYQKNLKNEQTKLANLNSENAFNEPSTIYGAKMMKNIAARIEQQQINNKKMEAIFFIPPILEADSNPSAIYRAYKSGDIDTLFTFNNPNDFTNLYELDRRIDSAHLNYQGAEEFTLLLASQFSQYLNNSGEKLISGKL
>NZ_CP046703|553986:640842|572609_573917_+|WP_114084426.1|DBSCAN-SWA
MTTESAAKPITPKFDNFQTLATEKGAVRAVAEKMFDLPAQINPPILGSRTRIWKQDPSVTELKLPRTVYVHTEVNDGPSDSQIRIKGVVPVPADVNRDFLPDPAANVEAFDAVHTYTVVRQVLTFYQRVLKKKLNWQWSQDNGEQAINVYPHAGETANAFYSREEKALKFFYFTPFKDSNLTSKVFTCRSLDIVAHETGHAILDSLKPEWILWNAPAQTGALHESFGDLTSIFLILSQLDLVEYIVAETKADLHQKNILAELAEEFGLAFNLRNGLRNADNNLKLSEVTPEVHDLSQVFTGGVFDTLADLFTSRRDPYVQDSAEVLYQTGKYLGEVVLRAIIESPNTNASFADVANAMIKIAQTDGNHDYAKFVQKNFEFREVLGSKAFGTHIDLSNFGMYPSRRCACGTMQHPQYRPKAAHLNGTNTDGMVKTP

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_114084414.1|553986_554400_-|transposase	IS200/IS605 family transposase	A0A7E6	Microcystis_virus	1.2e-29	47.4
WP_114084415.1|554453_555641_+|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A068A1P5	Thermus_phage	3.1e-51	33.6
WP_114084416.1|555680_556712_-	dihydroorotate dehydrogenase-like protein	NA	NA	NA	NA
WP_114084417.1|556729_560365_-	pyruvate:ferredoxin (flavodoxin) oxidoreductase	NA	NA	NA	NA
WP_159402433.1|561025_561217_-	hypothetical protein	NA	NA	NA	NA
WP_114084419.1|561291_563235_-	alpha-amylase	NA	NA	NA	NA
WP_114084420.1|563319_564726_-	Dyp-type peroxidase	NA	NA	NA	NA
WP_114084421.1|565088_565541_-	hypothetical protein	NA	NA	NA	NA
WP_114084422.1|565675_567304_-	NAD(P)-binding protein	D2XAA7	Marseillevirus	6.7e-20	24.8
WP_114084423.1|567332_569252_-	thiamine pyrophosphate-binding protein	NA	NA	NA	NA
WP_114084424.1|569288_571196_-	S9 family peptidase	NA	NA	NA	NA
WP_114084425.1|571587_571806_+	hypothetical protein	NA	NA	NA	NA
WP_114084426.1|572609_573917_+	hypothetical protein	NA	NA	NA	NA
WP_114084429.1|574447_574762_+	hypothetical protein	NA	NA	NA	NA
WP_114084427.1|574902_576798_+	M20/M25/M40 family metallo-hydrolase	NA	NA	NA	NA
WP_114084428.1|576891_577569_+	hypothetical protein	NA	NA	NA	NA
WP_159402434.1|577701_578715_+|transposase	transposase	NA	NA	NA	NA
WP_114084430.1|578855_580712_+	ABC transporter ATP-binding protein	F2Y165	Organic_Lake_phycodnavirus	4.6e-17	28.6
WP_114084431.1|581477_581828_-	cupin domain-containing protein	NA	NA	NA	NA
WP_114084432.1|583086_583767_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_114084433.1|583777_584209_-	hypothetical protein	NA	NA	NA	NA
WP_114084434.1|584922_589212_+	SDR family NAD(P)-dependent oxidoreductase	A0A2K9L3I8	Tupanvirus	4.5e-07	27.0
WP_114084435.1|589212_594051_+	amino acid adenylation domain-containing protein	A0A2K9KZV5	Tupanvirus	6.5e-111	27.5
WP_147262558.1|594193_594790_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_114084436.1|594799_595498_+	cupin domain-containing protein	NA	NA	NA	NA
WP_114084437.1|595510_596305_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_114084438.1|596398_601348_+	amino acid adenylation domain-containing protein	A0A2K9KZV5	Tupanvirus	7.1e-97	26.7
WP_114084439.1|601382_601961_+	adenylyl-sulfate kinase	A0A2K9L4R9	Tupanvirus	5.1e-31	46.0
WP_114084462.1|601990_603160_+	aldo/keto reductase	NA	NA	NA	NA
WP_114084440.1|603179_604979_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_114084441.1|604999_605929_+	isopenicillin N synthase family oxygenase	NA	NA	NA	NA
WP_114084442.1|605952_607596_+	dolichyl-phosphate-mannose--protein mannosyltransferase	NA	NA	NA	NA
WP_114084443.1|607650_608145_+	GtrA family protein	NA	NA	NA	NA
WP_114084444.1|608154_609291_+	hypothetical protein	NA	NA	NA	NA
WP_114084445.1|609332_610853_+	MBOAT family protein	A0A125RNP0	Pseudomonas_phage	2.5e-61	33.3
WP_114084446.1|610913_611888_+	hypothetical protein	NA	NA	NA	NA
WP_114084447.1|612091_616735_+	amino acid adenylation domain-containing protein	A0A2K9KZV5	Tupanvirus	3.1e-86	27.0
WP_114084463.1|616770_616950_+	hypothetical protein	NA	NA	NA	NA
WP_114084448.1|616991_618365_+	MFS transporter	A0A1B0RXG2	Streptococcus_phage	3.4e-33	31.1
WP_114084449.1|618594_620607_+	ABC transporter ATP-binding protein/permease	G9BWD6	Planktothrix_phage	2.6e-05	24.0
WP_114084450.1|620998_623806_-	bifunctional acetate--CoA ligase family protein/GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_114084464.1|623837_624293_-|protease	hydrogenase maturation protease	NA	NA	NA	NA
WP_114084452.1|624933_626004_+	Photosystem Q(B) protein 1	A0A1D8KNW7	Synechococcus_phage	8.0e-139	66.8
WP_114084453.1|626165_626921_-	TspO/MBR family protein	NA	NA	NA	NA
WP_114084454.1|627307_627646_+	hypothetical protein	NA	NA	NA	NA
WP_114084455.1|628043_629492_-	Ni/Fe hydrogenase subunit alpha	NA	NA	NA	NA
WP_114084456.1|629615_630254_-	CBS domain-containing protein	NA	NA	NA	NA
WP_114084457.1|630325_630871_-	oxidoreductase	NA	NA	NA	NA
WP_114084458.1|631113_631638_-	DUF3122 domain-containing protein	NA	NA	NA	NA
WP_114084459.1|631674_632391_-	bidirectional hydrogenase complex protein HoxU	NA	NA	NA	NA
WP_114084460.1|632885_633536_-	DUF938 domain-containing protein	NA	NA	NA	NA
WP_114080505.1|635428_636478_+	molecular chaperone DnaJ	NA	NA	NA	NA
WP_159402435.1|638467_639040_-|transposase	IS630 family transposase	NA	NA	NA	NA
WP_159402436.1|639581_640103_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_114080507.1|640158_640842_-|transposase	transposase	NA	NA	NA	NA

Sequences of DBSCAN-SWA_3

Nucleotide sequences of DBSCAN-SWA_3

>NZ_CP046703|1291643:1327239|DBSCAN-SWA
ATTACGTTACTCCACAACAGATATCAATAAACCACTTACCTAAATTTGGTAAATTATCTTCGGTAAAATTAGTCAAACGTTCAATCTTATTTTCAATTTCTTGCATAGCTTTTTTAGTTAGACGGACTCCGCTAGAGTAAGTCTGAGTAACTAACTTAACAACTGGACTTTTACCATTCCACGTCATAGTCTTAGCAAAATTTAATGCAGTTTCCACATCGTCTAAAATACTGCCATTCCAATGATTCTCCAAAACAGCCCAAGTTCTTTCAATTGGATTATATTTACTGTGATAGGGAGGGTAATAAGCTAAACGTATATTTAATTTGTATGATTGAGCAAATTCAACTATACGTTTCATAAACTGAGTACGTCGAGAACTATTTTCTCCTCCATTATCTTGATTAATAAGTAAAGTTTTTATTTCCGAAAATCGCCAGCTTTCTGATTTCCAAAAATCCCCTAAAATGTCAACGATAAAATCGCTAGTTACTTTGGATTCTGTAAAATACAAAAATAGCTCGTCAAGGTCTGGAAGAAAGATACCATAAGGAGCTACAGTTGTTTTTGGTTTGAAGTCGTGGTCATCAGTTTCTGTTGGTACTCGATTTCTACCACCACGATCAAAGGAGCCGATATTTACGCGAGCTTTCGCATCCAAGCTTAAACGTAAAATAGTTGGGTCATCTGAAGCTTCTTGGTGAACTATAGCTAATTGCTCAAAGATTGCATCAGTTTCGGGAATTTTTTTTGAGGTTGAATTTTGGCAACCCTCTTGAGGCGATACCCTAAATCATTTAACTTGACACGAATTGTTTCTGAAGTTGGTAATTCTTCTTCAGCATAACCAAATTTTTCAATTAATTGATGTCTTACAACAGATGCGCCCAGTCGGGTATAGAGTCTTTGACTTTTAAAAGTCGGGTCTATTTGACTTTGAGAATCGACTAGTTTTTTGATATCTTCTAAAAGAGTTGGTAGGTGTTCTTCTGCTTTTTTTCTTCCTCTACCTTGATAATTATCCACACAAGTGATACCACTATTTAATTCTTTAATTCCTTTACCAATAGTTACACGGTTCCATCCTAACTCTCGCTCTGCTATAGACTTTCCTCCGTGTCCTAATGCCACAACTGTTTGTGCAATGAACCTACGTTTAGCTGCTCCCTTTAATTGATGTGCGGTTTCCTTCAATAACTTTTTCAATGAATCTGTTAATTGTATTGACACCTCAAACATCCCAAAATCGAATCATCATTCAATTTACTACAACTTGGGGTGGGAGAGGCTGCCAACGGCAGCCTCTCCCACCCCCCTAACAATGATTATCATTTTTATTATCTGTATATTTTATTTTCTGGAAGTCCCTTATCGTGATCCTAATGTGGTAGGTTCCCCTGGCTCCCGTTCTAACTATTAATAATAAGTTGCATTCTAATTTTGCGTAAGTCTTAAAAATTATTATGGGTAAAGCCTGCATCAGCAGGCTTTGTTTGTATGTTTACATAACTCCAACCATTGGGGAGTAAGGACGTATCAAGTTTCCTTGGTTCAGTTGTTAATTAGGGATTTTTCAAAAATAAAATTGGCGAACAAAACAGCACCATGACACTTCTAATTTTAGCCATTTTCGTGCAAACTTAGTAAAGTTATACCAATTTTTTATGAAGCTGCATATAATTAGATCCCCCCTAGCCCACGCCAGTCGCTCCACTACAGCGCTTCGCGCATCCTGCGGCGGGGGAGACCCCATCGCTTTTAGCGTCTCCCCTTGGGAGAAGACCGCGCTGGCTCCCCTTGAAAAAGCAGGGCTGATTCATCCCCTAAAACCTGTAAAATAGCAAGTGTTTAGGGGATAAAAATTATGGGTGCGAATCTAATCGAACAGTTAAAGCAAGTGGAAGACTTTAGGACAAAAGATGGTCGAAGACATCCACTTTGGTTGGTTTTATTGTTTGTAATAATGGGCACTATGAATGGATATGTGGGATATCGTGGGTGGGGAGATTTTGTGAATAGGCATAGTCGGGTATTAATAAAGAAATTTGGTATCCAAAAACATGGAGTTCCATCTTATTCAACTATCCGACGTGTAGTGATGGGAGTAGAGTTTGATAAGCTGGCGGAAAAATTCAATGATTGGGCTAAAAGTTATGTTGAAATAGAAGAATTAGAATGGTGTGCTATGGATGGGAAAAGTATTAAGGGGACGGTGAAAGACTACAATTCATCTCAGCAAAATTTTGTCAGCATAGTATCAGTATTTGCTTGTAAAAGAGGGCTGGTCGTCGGGATGAAAAAATTTGAAAACCATGATAAAAGCGAAATCCAGGTTGTACAAGATTTAATTACAGCAATGGATCTACAAGGTGTGGTTTTCAGCTTTGATTCCTTACATTGCCAAAAAAAACTTGTGAGATGATTATAAAAAGTTGTAACGATTACGTCATTGCAGTTAAAAATAATCAGCCAAAACTACATAGCCATATTCAACGCATTGCTGCTCTGAGAAAACCAACAAGTCGTATAGTTGAGACAGAGAAAATTAGAGATAGATTGACAACACGTACTGTAGAAGTATTCCATGAGATCAAGGGAATTGATCCAAAATGGATAGGGATAAACTCTTTAATTAGAGTGGAAAGAGTTGGAACAAGAAAAGGCAAAAAATATCACGAAATTGTCTGTTATATTAGCAGTCTGCTCGGTACAGCTAAAGAATTTGCTATCGGTATTCGCGGTCATTGGGGTATCGAAAATCGCCTCCACTGGGTGAAAGATGTTGTTTTCAAAGAAGATAGTTCCACAATCCGTATGGGTAATGCTCCGGCAAATCTTTCCATTACCAGAGCAATCGCACTCAACATCATTCGCCGCAATAGTTATGCTTCTATAACAATTGCTCACAGATTTCTATCTCATGATATTGACAAACTCCTTGCCCTTGTGGAATGAATCAGCCCTGCCTTTTTAGGGGGGATTTAGGGGGATCAAGATATATGGAACTTCACATTAAATTGGTATTAGTTAGTGGTCATTAGTTATAATTTCAATAAAAATGGAAGATTCAGTATTTATTATATTTCTTTCCTTTGGATTTCTTTGGGTTTTGATGGGAGTTGTAGGTTGGATTGCATTTCTAAAATCTGAGGGTGAAGAAATTAAGTTTGGAAAATGGGGACTGATAGTTGCTATTCCAATCTTAATTCCAATAATTTTTACTTTGATTATTGGTGTTCTTTATTATAGGTAAAAACAGTAATTCTATCGTAATATTTATGTCAACCGCAGGTAAGCCTAAGTAGTTCACTTGTGAATTGCACCCCTGACCAAAATCACTGTACTTTCTACACCAGAGGCGATCGCTTCGGGAATATTACCTTGAATTGCCTGCTGCAATAATCCCTCGCGGGAAGCTCCCAAAACGACAACATCGTAACCTTCGGTTTTCACTAGGTTAATCACACCTTCAGCTACTGAATCAGCTTGCACTGGGAGCGCAACTACAGTACTAGACAATTTTTGCCGTCGCATTAAATGGCGAATAGCTTGTTCTGAAATTGACATATCCGGCTTAAATTCAAATGGCTTAAACACCTGTGTCAAGTGAATTTGCGGTTCATTCCCCAATGTAATTAAAGCAGGTAATAACTTAATCGCTAGCGGAGAATTGGGGCCACCAGCCATTGGTACTAGCCAGCGATTGAACTGGGGGCTGGAAATTAGGGAGTGCCCAGTTGTGCCTAATTTTACTAACACGACTTCGCAGGTGGCTTGGCGAATTATGTTGTCTACAACGCTGCCAAAAATCCGACCAGGGGTAGATGTGTTACCTTTCCATCCCATTAGAATTAGGTCGATGTGTTGTTCGTTGATTGTTTCTAAAATTGCTTGGGCGACATCGTGGGTAACTCGAATCTGCGTGTGCAAGGGGATTTTCCACTTTTTTGCTAAAACTTCTGCCTGTCTTAGCAAGCGGCGACTTTTTGCCGTTCTTACCTGTGTTTCTGATGGGGAACTGTGGCGGGGTATGAGCATAACTTGCACGCAATCTATTTCATAATGGCGATCGCGGGCAATAGCTGCTGCCATTTGTAATAAAATACCTGCGGTTTCGGGATTAGCTACTGGTACTAATAATCTACCGCTACCGGTGCTAGGCGATCGCGTTTGGTAAACTATGTATGAAGGTTCTGGTTGCAGCTTAGGAGTTCCATTTCCACAATTGAGATGATCTACTTCCGCCCGAATAATATCTGCACGGGTAATAATCCCGATCAGTTTCCGTCCATTCACCACTGGTAAGCGACTGATTTGATAGCGATCGAGTAAATACAACACATTGGCCAGAGTGTGAGTCGGTGTTACCGTCATCGGGACAGGTGTCATAATTTCTTTTAAGAAAATATCGGCTAAATTGCGATCGCGGAGCGTGTGCTTTGCACTCTCACGAATTTTCAGCAAATCTGATTGCGTCACAATCCCTACTAACTTGCTATCTTCTACCACAGGAAAACCGCGATGATGGGAACGAGCAAAGGACTGCATGGCTTCTTCTAAGCTCATCTCTGCATCCAGAGTTTCCACTCGTTCTTGCATCACATCTTTTGCAGTTAACTTAGTTAATGCTCCCTCCATTGGAAGTTGTTTGGTGAGAGTAATACCTTTTAACTCCAAAAGTTTCTCATAAAGCGAACCAGGTACTACCTTATCCGCAACCAGATAAGCTGCTACAGAAACAATCATTAAAGGTAGTACCAGATTGAAATCTGTAGTCATTTCAAACACAATCACAATTGCTGTGATTGGCACTTTGGAAACGGCGCTAAAAAATCCACCCATACCCGCTAGGGCGTAAGTAGTCGGAGAACCAACTCCAGTGATATATAACTCAGCTACACCGATGATATGTCCTAAACAAGAACCCAAAATCAAACTGGGAGCGAATAATCCCCCCGGCGCTCCCGAACCAAATGCTATGAGTGTGAGGATGAATTGGGCGGTAAAGGCGATCGCTGCTACTGTAGGTTGTGAATCTCCAGTAATGAAGGACTCCCGTAATCCTGTATTATCACGGAAGGATGCAGGGAGCATAGCTACGACAACACCAGAGATAAATCCAGCTAAAGCTACCCGCAGGGGTAAGCTGATGTGTAATCTTCTATAAAATTTAATACTAAATATTAAGCCACTATGAAACAATGCACCCAACAACCCTGCCAAGATCCCTAACAGTACGAAAAAGGGAATTTCTGGGATAGAAAATTGGCTGGAAGATTGCGTTAATTGCAGGTTAAGGTCAAAAGAGCCACCACCTAAGAGTCGGGATATCACCCCACCAATAAAGGAGGCGATAATGGCAGTTCCCAGAGTCAATCCTGATAAATCTTGGAGTAACTCTTCAACGATAAATAATACACCTGCGATCGGAGCATTGAAAGCAGCAGCCAAACCCGCACCCGCACCGGCTGCAATCATTTGCCGTCGATGATCGGGAGAAGTGGGAACCCAACGACTCATTCCTGCTGCCAAACCTGCCCCTACTTGGACAGTAGGGCCTTGCCGTCCTAGAGTCATGCCCGAACCGATGGCGATGATAGCGCTGAGTAACTTTACACCCGCTACCCGCCAGGATAAATTCACAGGCACATTGGCTAGACTTGCTTTGACTTGCGGAATACCGCTACCAGCAGCCTCTGGAGCCAATCTATCCACCATCCATCCAGCGAGAAATCCCAGGACAAGACCAATTACAGGTAATACCAGCCATGCCGGAAAAAGGTGGGTCGTATGCACTCGCCATGTCCCCAGCCATCCCGATCCTACTTTCAGGAACACCGCAGATAGGGCAGCAACCAAACCGATAACACAAGCTTCGGCGATCGCTAAACCTCTTCTAGGCTGCCACCAGGTGCGAAAACGCTGATTTAGAATAGGAAGAGACATAAGGGACTTCCAACTAAAAAATATCCCATCGCATTTAGGGCAGGGGGCAGGGAGCAGGGGGGGGAAAACTAGTCGTGTTGAGTCCAGAAATTGGAATAATTTATTTTTTGGAGTTCCCTAATTTGTGAGAATTAGGGCATTGGGCATTGGGCAATAATCGTTATTTTTCCCCTGCCTCCCTTGCTCCCCCTGCCCCCTGCCTCTTTAATTACTTCTCCCCGTGGTGGATAGCCCTTCTACTATCAGAGATGGAGTATAACAAGAACCATTCCAGTCACCATCGTTGCCCAGTGCAACCAATTGCTTCAGGGCTGTGTAAACATTACCTGCAACCATAGTATCCTTAACGCGCCCAATTACTTGACCATTTTGGACTCGGTAGCCTAAATCGACATTGATCGAAAAATCTCCAGAAATACTCCCACCATCACCCAGCATTTGATCCACAATCAAGCCATCATCTAGTTGTTGAATCAAATCTGGTAGCGATGCCGAACCTGGCTGGATGAGAAAATTAAATAAACCAGGAGTGGGATAGCTGCCTAAACCAGGGCGAAAACCATTTCCAGTAGTGTCAGTACCCAGTTGGCGGCCGGTGGTGCGATCGCCATAGAAATGCTGTAAGATTCCGTTTTGGATAAATACTAAAGATTGGGTTGGAGTACCTTCATCATCAAAAGGGCAACTGTAAGGGCCAGCTTCTGGATCTTGGTAGAGAGTGAGACTGGGGGCGACAACTGGGTTCCCTAAACGTTCTGCCCAAGGTGAAGATACTTCTAAGACTTGCTTGCCATTCAAAGCGGCTTGCACAGTACCCCAAAGCATATCAGCAGCTTTAGAAGTGAACAAAATCGGGACACGACCAGTAGGGGGCGAGACATTTTCTCTGGCCCAAATTAACCGTTGTAAAATTTGGTTAGCTAATCTCTCAGGGTGGAGTTCTCCCCGCTTGGTTTGACCGTCAGCAACACTTAAAAAATCATCGCCACGTACCCATTCTGCTGATACATAGCAGTTAAGGGTAGTATCAGTGTAGTAACAATCTAAACCTTTGGTGTTGACTATTCTGGTAGTTTCAATATCACATTCCCAGTCACCATTGCACACAACATCGGGATAGACATCGCGGATGAGTGCGATCGCTTCTTTGCCCCAGTCTACCAAAATCTCTATCGGTACACTTTCTCCTAAATCTGGGTAGGAGGGCTGAAAGTTAGAGCCTAATTCTACAGTTTCCGGTTCATTCAGGTGACTTAATGCCAGAGCTTTTTCCACCATCACTTCGGCTAAGACAGAACCGTAAGCCACCGTCAGCCCCGGACGACCGTTTCGCCAAAGCCGTAGTGCTGTACCTTCAGATTGGTTGGTTTCTAGCTGTTTGAGTCGGTTTGCCTCAAAAAACACTGGACGAGAAAGCGATCGCGACTGATACACCTCAGCAGCTTCTGCTCCAGATTTTATAGCTAGTTCCAGCAACTGTTCGGCTAGTGTATCTTGTGACAAATTTTCAGAACCCATGACCCTTAGTGAATTGTGGATTTTGAACCGCATATCAACGCACCTTGGAGAAAGTGCGATCGCTAAAAACCAACGATCGGGCTTTCTGCCGATGGACGCAGATAACTATCCAAAAATCATCAGCGTTTCCTTACAGTTACGATTTGGAACCGCAGATCAAAACTGATGGACGCAGTTAATTATCCCAAATCATTGTCATGTCTCAACGGATCTAGTCATTTGTCATTTGTCATTGGTCATTAGTCCCCATTCCCAATTCCCAATTCCCATCTTCAAAGATTAACCTCTTGCAATAGCCAAAAACCAGCAAAAGATTCTGCTTTGGGATCAGACTGTATACCAATAAAATGCACTCCGTTAGCTTTTTGCTTGGCTTCTTCAAAACCTTTAGCCTCTGCCAAGACTTGAGGTTTTTTGATATTTGCCACAATCCAGCTTTCATTAACACCCGTTTCTAAAAGCAATCTCGGCTCTTCACTGGTGTCAAATCTTAAGAAAGCTAACTCCAAACCAGACATCCAGCCAGCCAAGGGTAAGGCTCTCGGTGAGAAAATCAAAATACCAGGAATACGGGCTTCGGGTGAAACTTTTGCCAATTCTAAAGGGAAAGCTTCACCAAAGCCAATTTCCCACTCTGGCATTTCAGCCAAATCCGCAGCATCCAAGGTAACAAATACCCACTGTTGCCCTTCCAAAGCATCTGGTAAACGTTGCGGCAAAGGTTTTTCCAAGCGGACTGAGGGATTAGTCCCCCCTTGATACCCCGGTTCTTGAGGATACACTTCCTTCATCCGCTCTTCTAGCCATTGGTTAAGAACCAGAGTGCGGCGGCTAGGCTGGGCGGGAATGCTTATATCTTGACAGGCTTTTGTAATCATGTTGTTCATTTGGCGGCGGAAAAAGCGGATTTTAATTGGTGCTTTTCCAGCTTGGTTAATAGCCTCTTGCAATGCTGTCCGCAACCAGCCCGAGTTTACCTGGGTACTGGGACAATATTGAGCATAGCGAAACAAAGAATCTGGTTTTGTGCCAATATCCAAGGGGCTTTCGCAGACTAAGACTTCCCAAATTTTTTTCTGATTATCGTCCAAAATCGGACGGGAGTAAAAATCGATTTCCCAAATACTGCCCATGTTTTGCGGTAAAAATCTGGCTGCTATGTTTTCCTGATATGTTGATCATACGAGTGTTGGGGCAGCATTGGGCATTGGGAATTGGGAATTTGGAAGAGGACTTGGGGACAAGGAGAATTGGGGACAAGGGGAAAGACTTGTTTCAAGTTCTCACCTCTTGTCCCCTTGTCCCCCTGCTCCCCATTCCCCATTCCCTCTCCAAAAATGAATGTAGAGACGTTGCATTGCAACGTCTCTACAAGGGTTTCAGGTAACGCATAATTAATTTCTGGAGATGTCTAGTATTCTCATCTGTTGAGTATATGCTGTGTTGTGTTTAGATTTGAGGAAAAATAGCGATCGCTAAAGTATCTCCTTAATTAACCACGATTGATCCAAACGCCTCTGAGTCCTGCTGCTTTAGCGGCGTAGTAGTCTTCTACAACGCTATCGCCAATATGCCATGCTGCTGAAGGGGAACATTTATGTTTATCTAAGGCAATAGCAAAAATTTGAGGATCGGGTTTAGCTGCACGTACCTGGGTAGCAATAGTGACGGAGGTAAAAAACTCTCTCAATCCCAAACTTTGCAATACTGAATAAATCCGGGAATCAAAATTGGATAGCACCCCCAAAGTAACCCCCAACCGTCGCCAGTTGATTAAAGCTGGTAAGACATCGGGATAGACAAACCACGGTTCGCCAGTGCCAAAGTGAATGTAAAGTTCGCTAAAAAAAGCCGAAAAGTCAGAAAATTCCTTGAGGACACCTGCACTTTCAAAAGTGTTCAGGGCAATTATCCGCCACCAATCAAACTCGCGCTGGGGAATATCTTGGAGTTCTGCATCTGGAAATATCGGCGGCGGGGCTGCTTTAAAGCTTTTGATGAAAGCTGTATTCAATGTTTCGGCTGGAACCGTCACACCAAATTCCTCGGCTATCTGACTATAAACTTTACCTACACTGCCTTTAACATCGAAGAGTGTACCCACAGCATCTAAAAAAATAACTTTCGGTTGTTCCATCAAAGTTTGAAGATTTTGAATGTTAGATTTTGGCTCGTTAGAGAGGTTCTGTGGGTAGAGTCTAGCATCTGCTAAGTAGCTTGACGAAAATAAAGTAAATCATTGTCATTTGTCATTTGTCATTGGTCATTAGTCTCCATCCCCCATTTCCAATTCCCCATTTCCAATTCCCCATTCCCCATTCCCAATTCCCAATTCCCAATTCCCAATTAAGTTACTTAGAAAGTGTCTCGATGATTGGACGTACTAGCCAATTAAAACCAACTTTGAGTTGATGGTCTAAAGTTGGCAACCTATATAAATAGGCAATCCGGCGGGCGACGGATGCCAAGGGCCCATCTAGTTTAATTCCCAAACCAGTAAGGGTGGCGTTGTTTTTACCCAATGTCATCATTTCTCCTAACTGTTGGTAGTGGAAGGGAAGGAGGGGACGATTAGTGAGACTTGCCCAAATATTCCAAGCAGTATAATCAGCTTGTTGAAAAGCGGCTTGTGCTGTAGCGGGGACTTGCTGTCCTTCAACATCATGAGAGTCTGCTAAATCTCCCAAGGCAAAGATTTCTGGATGATCAATCACTTGTAAATTAGATGTAGTGCTGATTTGACCGCGCTGATTTTGCTTGAGGGGAAGAGATTTCACTACAGGCGCAACCCTATTTCCCACGGTCCAAATTACCAAATCTACGGGAATCGTGTCTAACTGGCTTTTGTACTCTAGGGTGATGCTATTTTGCTCTATTGATTCGACTTTGGTTTCTAAGTCCAGAAATACGCCACGGGCTTCTAGAGCTTTTTTTGCTGCTTCCCGGTTAAACTCTGGAGAAGTTCGCAAAATTTGATCGGCGATTTCAACGATCCGAAAGCGTCCTCTTTCACCGAGTCTGTCGGCTAACTTACAGGCTAACTCTACACCACTGTAGCCAGCCCCAATAATTGCCACCCGAATTTTATCAGCATCCGATTCTTCTAAAAATCGCAGGCGTTCTTCCAAGCGATAGGCATCAGAGATGGTGCGGAATGGGTAGCCATAGGTTGCCGCACCGGGGACTAAATCTAGCGGTGTCTCACCTCCTAGTGCCAGCACTAAGCGATCGTAAGGGATTTCTGGCCCTTCATGTATATTTACCCGTTGCTGGTCGATGTCAATTCCAGACACAACTCCTTGATAAAAGCGCACCCCAGTGCCTTGTAAAAGTTCTTCAAAAGGTGGAGCAATTTCCCAAGTTTGCAGTTCGCCAGTGAGTAATTCGTAAAGTAAAGGGGAGAATAGGAAGCGATCGCTTTGATCTACCAAAACAATTTCGGGTTTTTGCGTAGATTCCCAAGGTAACTGGCTTAAGCGCAAGGCTGTGTAGAGGCCACCAAAGCCTCCGCCAAGGATACAAATTCTAGAATTTTGTTGAGTCATCGATTTTATCTATAAAAGGATCAATACAAGCTGGGCAACTAACTTCAGTCTAGTCAGTTAAAGCGGACTTTTCAAAATCACATCAAGTTTTTGAGAGATTAATCATTAATGGTCACAGTTATCTAACGGTCGATTCGCTATATTTAACGGTTAACAGGCAACGGCTAAAAGGAGTTAAAGAGATGGAAATTAAGCCAACTGACCCATCGCTAGCACTCAAGGAAATTCCCCCTGGCTATCTCAACATTATGGGTTACGTCGATCAATCAGAAGTTAATGGCCCTGGTTGTCGTGCAGTCGTCTGGGTACAAGGTTGTCTTCGTGAGTGTCCTGGCTGCTTTAATACTAACTCTTGGTCATTTGAGGCTAACCAATTGATTGCTGTTGATACCCTTGCCGAGAATATTCTCAGCAATCCCCACAACACGGGTGTAACATTCTCTGGTGGAGAACCATTTTGGCAAGCAACTGCACTAGCGTCTTTAGCTCGTAAAGTAAAAGCTGCTGGGTTAAATGTAATGTCTTTTTCTGGGTTCACTCTCAAGCAACTACAGTCTCAATCTGCACCCCCAGGTTCTCAAGAATTGTTAGAACAACTTGATATCCTAATTGACGGGCCTTTTGTACAATCCCTGGCAATTAATTCTCCTAACTCTCCAGTTTCTTCTAGCAATCAACGGGTTCGTGTGTTAAACCCGGCTTTCCAAGACCAAATTACTTGGGCTAGCGATCAGATAGAAGTCCACATCCTCAAGGATGGTGGCCGCATTGTCACTGGCTATCAAGGTGGGCTGGAATTAACGTAGGGAATTGGGAATTGGGCATTGGGCATAAAAAATTTAGCCTCAGAAGATCAACGTCCACCTTCTGAGGGTCAACGTCCACCTTCTGAGGTTCAATGTTCACCTTCTGAGGTTCAATGTTCACCTTCTGAGGTTCAATGTTCACCTTCTGAGGTTCAATGTTCACCTTCTGAGGTTCAATGTTCACCTTCTGAGGGTCAACGTCCACCTTCTGAGGTTCAATGTTCACCTTCTGAGGGTCAACGTTCACCTTCTGAGGGTCAACGTCCACCTTCTGAGGTTCAATGTTCACCTTCTGAGGGTCAACGTCCACCTTCTGAGGCTCAACGTTCACCTTCTGAGGCTCAAATTTTACTCTCCCGCTCACTCATCGAAGAAAAACTATATGTAAATGCAGCTTTGTTTGGGACAGATTACATTTAATGAAAATACTAGACCGAAATTTGACTAAACCATTTAAGACAATTTTTACTGAACACCGCGTACTTTGGGCTGTTTTACTCCTTAGTGCAGCACTGGTGATAACGCTAGCGCTGTCACTTTCTCAAGGAGCAGTACCTTTAAGTATGTCGGAATTTTGGCAAGCCATACTCCGCAAAGGCGATCCAGTTAAACAGACAATCTTCTGGGATTTACGTCTCCCGCGCATTACGGCTGCTCTCATTGTCGGCGCAGCTTTGGGAATGTCAGGAGCATTACTGCAAGGGATGTTACGCAATAGTCTTGCCGATCCATTTATTTTGGGCATTTCTGCGGGTGCTGGATTAGTTGTGATTGTGATGATTGTGTGGCAAATATTCCCGATCGCAATTCCTTTAGCAGCGTGGATAGGGGCAATTTTGACTTCTGCGATCGTTATTTTACTCGGTCGTGCGGGGTCGGGAATTTCGGTTGAGCGGTTAATTTTAGGCGGTGTGGCGGTGAGTTCTTTATTTGGTGCTGTACAAAGTACATTGCTGCTTTTAGCTGAAGATGGTCAAATTCAAATTGCGCTCAGTTGGCTGGTTGGTAGTCTTAATGGACGCGGTTGGCAAGAAATTTCGACGGCTGGCCCTTATATTATTGTTGCATTGATCGGGGGATGCTTACTGGCGCGATCGGTAAATGTGCTGGCTTTAGGCGATGATTTGGCTGTGGGCTTGGGGGTTTCGTTGACGCGATCGCGTTTGTTAATTGGTGGTGTCGCCACTCTCTTAGCCGCAGGTGCAGTCAGCATCAGTGGTTTGATTGGATTTGTTGGTCTTGTTGTCCCTCACGGTGTCCGCCTCATTGTTGGTACAGATCATCGCTTTGTTTTACCGCTTTCCGCCCTTGCAGGTGCATGGTTACTGACTTTTGCAGATTTACTCTCTAGATTAGGAGCAGTAGAACTACCAGTAGGTTCTGTCACCGCGTTGCTGGGTTCACCGCTATTTATCTGGTTACTTTATCGTCGTTCTGCTGGGTTTAATAAATTTTGAGCTAATCCGCTTGGATTAAAGCCAAAATTGTTTTTTAGTTTACAGCTATTTTCAGGTAAATAGACCACGCGGTAGGGGCCAATACTGCTCGGTTTTTGCATTTTTAACTCGGAATCGGGTTTGGGGAAAAGGTTAAAGGGTAAGGGTTAAGGGTTTTTTCTTTCCCTTTTGCCTTTCCCCTTTTCCCCTTAACCGAGAAGTATTGCGGTAGGGGCGCAAGGCCTTGCGCTATAAAATAATATTCTTTAAGACTCAGTGTATAAAAAACCTGCCAAATTGGCTATATGAGTTTGGTTGTCTCTGGTAAAGTATTAAAAGTAAATTACTTGTGGGCTATATTTACCGAGGTTTACTATACTTTTAAAAGCATTTTACTAAGTCCGCTCATTTTGCTTTGCTAACGGAATAATAAAAATTGCTGGTGTATTCACTACAACAGCAACAAGCAGAATGATCAGTTTTGGTTTATTTACCTCGTCTATTTTAAAATAGACGAGGTATTTTTATTTATTCACTTGCATTTATACCAATTACACCCATAATTATTAGGGCGATCGACAAAAGTTTGATAAATGTAGCAGATTCGCGAAACCAAATAATACCAATGATTGCAATTAGGACAGTTCCCAACCCAGCCCAGACAGAATAAGCCACGCTTACTTCAAGTCTCTTGAGAGCAAGAGTTAAAAAACTAAAACAAAGTCCATAAAAAACAAATATTAATACTGAAGGGACTAATTTAGTAAATCCTTCTGATAACTTCATGCAAGTTGTGCCTGAAACCTCAAAAAGTATTGCTGCGATGAGATAAATCCAACTTGTTGACATATCTTTTGTGAGCGGTTTGTTACCAGTCTTTTATTATCTCTATGAAAACAAGAAAATACAACACTTTTAATTTATATTATTGATTGAGCAAATACCCTAATTGCAATTATTTGTGAAACTGCACAGAATAATCTGGTTCAAAGTTGTGGCAAAATCACCTTATTCAGAAACAATCTAAAATGTAATCGGTATATTATTGTTCCTCATAAATAGGTTAGTAATTCCGATGCCTGGCTTCTCAAATAAGCTAGGTATTTATCTAATATTAGCTTACAGGCATATTATAGAAATTATAAATTAGAGAATTTTTAAATTCAAGTCTCTATTGTCGAGTTTACCGAACTTCACAAGTTCAGATTACCCTACATTTATTTTGGTTCGGTAATCATCATAAATCATGTGATAAAAACCGAATTTATACCAATTTAATATGAAGCTGCATAGAAAAGAGCTTCGAGAATAAAGTTATAAGAAGAGATAGATATTACCTGCTCAAGTGTAAGTTGATTAAATATTTCTTGGATGCGATCGCGTAAATTCTGTAAAGAAGAGAAAAGCTGATTTTTGAGTGGTTTCTTGAGGAGCTGCCAAAGCCTTTCAATGGGATTGAGTTCAGGGGCTGAAGGTGGTTGAAACAGAGGAATAATATTTTCTGGCCAACGAATTGCTGAACTTGTATGAGCAGGTGCTTGGTCAACCTGTAAAATAGCGTAATCCCCACCTAATTGTTGAGATAGCCAGTCCAAAAACTGTTGAAAACACTCGCCATTCAGTTTTGGATATTCATAAAGAAAATGATCTCCAGTCAATGGTTCAATTGCACCATAAATCCAAAAATTTTCCCGTGGCCATTTCACCTCAACAGTAGGCTTAACTCCAGAGGCAGTAATCACTTTTCCTGTAAGAGTTTTCAGTCCCACCCTCGTTTCATCCTGGCACAGGTAGCGAACACACTTGCCGGGTGCTAGATGTTTTTCTAGACAATTCAGAATGATACCGAGTTTTTTTTAAACTCAGATACTAACTTTTCATCCTGCTTATGGCTTTGAGGACGTGGTACTTTTAGTTTTGCCCCTAATCGATATCGAACCAATGCATAAACCGTTGCATACTCGATATCAAGCCCCTGCTCTTGCTTTAACCACTCTACTATTGCACCATAGCTACTAAAGCCTTTTCCTGTTTTTAACTCCTCTTCAAGTGCCGTGATCGCTCCTTCAGGAATTTTCCGTTTTGCTCCCGGAGCTTTTTTTATTTTCAATAATTCATCTAGCCCACCCGATCTATATTTTTGTAACCATCTTGTCACCGTTGATGTATCTTTAGCCAAGCGTTTTCCAATATCTTGCTGCTCCTTGGCCTGCCCGCTTTTTATCCACCACAGCATAATAAGTTTTTCTTTCTGGTTCCCTAAATTAGCTGTTTGTAGGCGTTTTTTAAGTTCTTCTTCGCTCTCTGCGATTTCAATCTCAAAAGGGCGGCTCATGGTTCTTTTAATTTATCGAGTTTGTTTTCTCTATTATATGCAGCTTCATATTAAATTGGTATTACACCACTTTTATTTTTAAATACTATGAAAAGCAAGGAAATAAATCCTCAATTAGTCGAACAGCAAACATACTGATTATACGAGGTAGAAAGATGACATTAGTACGTTTGAACCCTTGGCAAGAATTGAACACAATACAACGTCAAATCAATCGTTTATTTGATGAAGAAACTTTGCCATCTGCATTTTTAGACAGAGGCTATGCTAGAGTTCCTGCTGCTGAGTTAAAAGAAACTGAAGATGCAATTCATCTAAAAGTAGAACTTCCGGGAATTGAAGCTAAAGACCTGGATTTGCAAGTTACAGAAAATGCTGTATACCTCAGTGGTGAGCGGAAGTCTGAAGCTAAATCTGAAGAGAAAGGTGTAATCAAAAGCGAATTCCACTACGGTAAATTCCAACGTGTAATTCCTTTACCTACTCGGATTCAAAATACTAACGTCAAGGCAGATTATAAAGATGGTATCTTGAACCTGACGCTACCCAAGGCTGAAGAAGAAAAGAACAAAGTCGTCAAAGTTAATCTAGCATCATCTGGCTAATTTCTGCTTTATATCTGCTAGCTATTTATTAAACTAAATAAAAAGCGCTCTCCAAAAAGGGAGCGCTTTTTAATGTGACTAACTGAGGCTATATAGATTTATTAGGAAAGTGCAAAATTCTAAATCTTGTAGAGTGTGTTATCGCCAAGAGTACGACATTACATCAGATTTAAGGTGCGCTAGAACGAATGTTCTAACGCACCCTACAATATTTGCTCTTGATTAAATCTACATTTCTTAGTTAACCGTTAAGCTCATCTTCTTGATTGGTTAGGATTACACAGTCAGAAGTAGGCTTGGCAACGCAGGTGAGAACCCATCCTGCGTCTATTTGATCGTCGTCTAAGAAGTTCTGATCTGATTGGTCAACTGTACCTGAAACCAGCTTACCAGCACAGGTTGAGCAAGAACCAGCATTACAAGAGTAAGGCAAGTCCATATCATTTTCTTCGTTAGCGATCTCTAAGATGTAATCATCTTCAGAAACCTCAATTGTTTTTTCTTCATCTGGAGTCTTTAATGTGACTTTATAAGTTGCCATGTAACAATCCCTAGCTAAATCTGAACTACATTGTTGATCCTACGGGTTTATGTGCTGCTAGTCTAGAGTTAAATGTGGTTGATTACTCTATATCCTGAAGTGCTTAGTGTGAATTGGAAGTGAGAGTAAAAAATTCTGCGATCGCTTCAGCAAATCCCTCAAATGAACTATAATCCCTAGACACGATGGAGACATTCACACCCAACTTCCGCGCATTAGCAGTTGTATAAGGGCCAAAACATGCAATAATGCAACCTTCATAGTCACTTTGCGAGTTGACCATTGTCAAAAAGCTTTCTACTTCCGCCGTGCTACTAAAGGCAATGACATCAATCATTCCTTGATGTATCAAGTTTAATTCAATACTATAGATACTTGTGTCTAAGCCCTGTGTAATATATGTGGGTACACGAGTTACTTCTATGCCCAATTGCTGCAAATCCGTAATTAAATTGGGTACAACATCAGGCTCAGGCAAACCAACAACTTCTGGTGCAGGTATCAGCACTTTTTTGTTATGAATTTGCGGAATTTTCGCTAATTCCGCCACAATTCCGGCTGGACTAGATTCTGTTGGAATTAAATCTACCTTGCCACAAAAAGACAATAGGCTTTCTGCATCTTTTCCCAAAGCACATAATTGACATTTTTCTACCACAGATACAGGAATATTTAAATCATTCATCCGGTGAAAAAATGCAGTGATGCCATTTCTACTTGTGAAGACAATCCAATCAAATTCAACTATGTGGTTGAGAGCAGTATCTAATTTAGTGTAGTTTGATAAATAGCAGGTTTCGATAGTAGGCATGAAAACAGGTAAACCACCTTGTTTGATAATTTGTTCAGATAACCTATAAGCATAATTTCTCGGTGCTGTTACTAAAATTCTCTTGCCATATAGAGGTAACTCTCTAGATGGAGTGAGTATGTTGAGTTGTTTTGATTGGGTGTGCATATTTGTTTATCAATAAATGATATAAGCTCAACCTTATCCAAAATCTGACTTTTCACGGCATCTGGAAAACCTCTCTCTAAATCTCTCTCCTAAGAGGCTACGGTGTACACACAAGTCTTAAAATTCCCCCTAGTACTTGGTTTCGTCATCTAGCTTTAGGTTGTGCGATGGCGTACCTGCCCGCCGGAGGCGATCGCTCTGGAAGCCTGTCCGTAGCGTTCGCGCAGCGTCTCGTAGAGAGGAGGAACGACGACGCAATCGCTTTAAGCAGGGGATTATGTGATTACTTCGCTCCGTTATCACTGCGCTCGTAATGACAATTTAAGGGGTCTATAACGTAACATCGTATCGAGAAGCATCCATTCCCAAGATTGCATTCCCCCGGTTATTCGGATCAACATCACCACAAATAGAACTATAATCCCTGGAGGTGCAGCCAGCGACCACAACCCAAATTCTTGGCAAATACGATTCCAGATTCCCCTTCTCATTTAATTTAGGATTTATTTTCCCTATATTTACAGCATATTTAAGGATGTATTCAAAACCTTTTCCCTTTAAGCGAACTGTATTGCTATGCCTCTAGCGTGTGGTCTATTTAGGTGAAAATAGCTGTAATTAATCAATTAAACCTTCTTCACGGGAACGAATTTCGGTGAGGATTCGCATATTCTTACCACTTTGTTTGCAGTCTTCAGGATACACCCCCAAAACATCCTGAATCTTCGTCCAGTAAGTACATACTGCTCGTTCCGATTTATACATTCTGTCTGCGATCGCCTTATCTGTCAAACTCTCTTCAAAAGCCAAACGCAACACATCCAACCATTCCGGCTTGAGTTCGATTCCTGTTTTGATGTCTTTTGTATGAGTTGCACCCTGAAGTGCTAAATTAACCCGCATGAGCATTTCATCTTCGGGTAATCCTTTATCTGCGATCGCAAACCCACCTTGATGATTATCAATCTCGTGTTTAATTCTGATTAACGCCTTCACATAACTAGTTTGCACTATGAAATTCTGATGGGGATATTCTTTAAGTAAAGTTTGCAACAGCTTAATTCCGGTATCAATTTCTGCTGTCTCCCCTTGGCGATCGGGAATTGATAAATCCATCACAATCAAGTCAAACTGGTAACATTGCACTTGAGAAAGTGTATCTTTTGCCGTCTGAGCCTTGATAATAATAGCTTCAGGATACTTTCGATTTAAGACATCAAGAGTACCAGTCAAAATTAATTGGTGGTCATCGACAACAAGAATACCGAGCTTCTTTTCCACTGCTAAATGCCCATAAAGTTGATGTTCTTTCAAACTTTTCATCACCATATTTTTATCCAAATTAAAAGTTTTTTTAAGCTTTACTACTCAATACTTAGCCATTCAAGTAATATTTAAAATCAGCACTCTTTTAAATGTCCTCTTTAAAGTCTCCGCCTATTTTAATTGGAGATGAATGTCCTACATATACAGAAAAGTGCAAATAATGCTGAGAGGAGATTGTTCATCACTACTCAATACTTTTCGGTTAAACCCAATAATCTCTCTTTTGGTCTGGGGAAGGGTTAAAGGGCAATGGGGAAAGGGAAATTCAAACCCTTTCCCTTTCCCCTTTCCCCCTTAACCGAAAAGTATTGCATCACTACTAGCTTATTTTCAATTCATGCACTGAGAAGGTTCTGGGGATCTGGATATTTTAGTATGATTTTTTGACAATGACAAAACCCGCAGATGTCAGCACCAAACTCTTAATTAGCCTTGCACCCGACAACTGGGTGAGATGGGTAACTCAAATTCCCAACATTACAGTTGAAGAAATTCTCAACTCAGAATTTCAATGGATAAGTAGGGAAAGTAATGTTTTAATGAGGTAAAAAAACTTATGGACTGGATAGATTTTTTTCTAGTAGTCTGCCAACCCAAAAATGCTGCGTGATGCCTGGGGAAAGGGTAAGGGGTAAGGGGTAAGGGATTTGAAACCTTTCCCCCTTCCCCTTTCCCCTTTACCCCGCCAAGTTCACTTGGCGAACTACTAGCCTGGTTAGCAAACCTATATTAGGGCTATCTTTTTTTACATTATCATTAGTAAGTGTGGAGCAAAGGCACTCGTTTCCCATACAGATAGAACAAAGGTGATCGTCCTGTAAGGACGGGGCTTCATACCCATTTTTTCGGTGAGGCGATGCTGCAACATCTGATAACTCAACAATATTATTTCGCATTAAAGCTTTTCTCGGCACTGGGCTGCGGGCTGATAGCCGGAGTTTTCTTCGCCTTCTCGACTTTCGTGATGAACGCCCTTGCTCGGCTGAAACCGCCACAGGGCATTACCGCTATGCAATCCATCAATATCACGGTAATCAATCCATTTTTTATGACAGCGTTTTTGGGAACGGCTGCGGCTTGTATCTTTCTTTTAATCTCCTCGCTATTAAAGTGGCATCAACCCGGTGCCGCCTACTTGCTTCTCGGCAGCTTGCTCTACCTCGTTGGTACATTAGGCGTGACAATAGTTTTCAATGTACCGCTCAACGAAGCCCTGGCGAAAGTCGAGCCGGATAGTACTGAAGGTGCGAGCCTATGGTCTAGCTACCTGACCAACTGGACAATCTGGAATCACATTCGGACGGTAGCGGCGCTAGCAGCAGCAACATCGCTCACCATCGCGCTTTGTTTGGGTTCAAGAATCGTAGAGGGAATCGATAATACGGTTAGGTAACTCCGCTACTAATGGGTAAAGTAGGTCGGCGAAATTAAAGCTAACTGGCTAAGGCTGTCATTTGTTCTTTGTCATTGGTCATTAGTAAGGATTTTAAGCCTATTTACGTTTCGTAGCAGACTTAGTTTTTTGTGACTAATTAGTAATTATTTGCTCAACCATTCCTGCCATTTTTGAGCAGCCTTGTCACGTTCTGCTTTTTGGCCTGCGGGATCATAACTTCCCAAACTCTGCCATAACTGATTCCAGTCTTGCCCTTGGGGTAGCTTACTCACTACAGCCTTAACAATCAAAAAAGCCCGCTCACGAGTGAGATCGTTTGGTGCTTGCAAAAGAGGAATTACCAAAGGTAAAACTTCTTTTCCGCCTCGCATTAAAGGATACATCGAAGCTGTGTAGGGATTGTGCAGAATGTCAGGGTAATCATCAAGGGTAGCGACCAAAGCGGATAATGAGCGTTTATCTCCTAATTGGTGTAGGGCAGTGGCAGCACGGGCACGCACTTCTGGATTAGTGTCATGGGTGGCTTGGAACAAAGCATCGGCACTAGCGGGATCGGCAATTTCGCTCAGTCCCTCGGCTGCAAGCCGACGGGTACGGGGGTTGGGATTAGTCAAGGCTTCCAATAAAACCGGGGTAGCTTTTTTGCCTAAACGGATCAATTCACCTAGTGCTAAAGCGCTGGTGTCTTGATCTGTGGAGTAGAGACGTGTTTTGATCTGCTCCATAGGTGTCGCGGTAGCGTCTTGATTATTCATATACAAATTTCCTCCGATGGCCAGCATCACAACTATCACGAATATTCCTATTGTTCTCAAGATCAAGGTGTCCCTCCTCCCCCTGCTGGTGCTGCTGGTGCTGCTGCTGGCACATGCTGAAAGCTCAAGACAACTCGGCGATTACCCCGACGATTCGCTTCTGTATCTTGGTTAGTTGTGGCATCAGGGGTAAAGTCTTCGGTTGAACCAGAGCCGATAGTAACAGCACTAATTTGAGCTTCAGCTACACCCTTAGCACGCAGGGCTGCTCCCACTGCCTGCGCTCTGCGTAGAGATAGATCGAGGTTGTGCTGAGATGCGCCGCCGCGCCTGTCAGCGAAGCCTTCAGGAGTTACTTTGACATCAGGGAATCGCCGCAGGTAATCTAAGAATGTATCAATCTTACCTGTTTCGCTGGAACTCAGTTGGTCGCTGTCGAAATCAAAGTAAAAAATGACTGGTTCGTGTACGTAAAAATCTTGATGCTTCTGCAAAGCTGCATCGAAGGTAGCAGATTGACCATCCTGTGCTGATGCATGATCGTTCTCAACTTTGCCAGCACGGATTTGGAAGCCCCAATGAAGCGCTCCATAAGTTGTCATGGTGTCTTCTCCCTTAGCCACCGTCTGAAAGTCGAAATTAAACTCACCAGCCCCTCCGGGAGCATCGGTTAGTTCTGCTGCTTTGATATCAGTGGGGTCATCGGAGCGTTTGTAACCAATAGTTGCTCCGCTTGCACCACTAGAAGAGGGTCGTGAAAGTCCAGGGGTTGCGGGATTGGGTTGGGCTGGGTCGTTGCCAAAGGGGTACTGGGCAGGTAATGCACTTCCGGCTGCGGCATTGGTTCCTGTACCACCGTGGGCAGGTGCATCATTATGCAGCGCATCAGTGAAATATCCGCCCTCAACTCCCGTGGTGGCATCAGCAGTGGTACGGAGGCTAGCACCACTAGCAGCAGGTAAAGACTGAGGTTCGACATTTGTACCTGTAGCATTTGTCAGACGCACAATCTGAATCAGTCCAATCTGGTTAGAGTAGGGGGCAGTGGTTTTGGGTTTGAAACGAATAGTAATCGGTAGACTCGCGCCGTTTGGTGTGGCATTTACTTCAAAAATACCGTGTGTCAGGTCGTATGTGGGGTTAATTGCCCGTTGAATCAATTTTCTCTGGGCTGTCCCTGTCTGCTGCACCACATGAGTCAGTTCATGGGCGGTTAATGCATCATTACCTGGTGACTTACCCGCACCAAAGAAAATGTTTTGCTGGTGCGTAAATGCCTGGGCATTTAAATCCTGATTCATTTGCACCGATTGAGTGCCTGTATGTACCCGTACTTGACTAAAATCTGTACCAAAGCGGGGTTCCATAAAGGAGCGCACGGCATCTGGTAATGGGCTTCCTCCACCTTCACTGCTGTTTAGCCGACTCTCAAAGTTATCCCCAGTTTGGAAGCTGTCATTGGTAGCGAGTTGTAGCGATCGCTTAGTTTGTAATTCTTCTTCTGGTAAAATCTCTCTTTGGATGGGTGCATTAATAAGTTTAGTTTGTAACTCCTCTTCCTCTTCTGGCATTGCCTCCCGTTGCACTAAGGGAGTTATGGCAGAGGCTAGAGGCTTAGTTTGCACTTGGTCTTGAGTCTGTGTATTCTGCAATCCTATTGGCTCTGGTTCAGCCATTCGCATAACCTGATCGGCAACTTGATCGGCTTCCTGCTCATAATGATCGTCTGGCGCACCAACCGTGAGTTTTGCCTGGGGACGATGCAAAGATATGCGACTAATATCATGACTAAGGGGCTGTTTGACGGCTTCTGGTTCCAAGAATTGCTCATTAGCAGACTGCACTTCTTGAAGCTCAGTTGATGCCTCAGTTAGTCTTTGGATTGGAGGATTATTTGTTTGTAAACCAAAGCCACGCATTGGAGAAGCCAGTGTGGGAATAGTTGATAAGGCAAGGGACGGATTTAGAACAGTGGATATACCTGCTTTTTGGCGCTGAACTATGCGTAGATGCCCAGAAGCTTGTTGTCCGTCATTGCTCATATCACCCTTCCTTCATTTATGGTTCAACCAAGGCATATTGATAATACACATCATAAAATTTATCTGATTGCGATCACTATGGACTTAAGTGGAAATTATCTCTTCCATACGTGAAGCTTAGATGGCTTTAATAAGCTGCAATCAAGTGACCATCACATAGCATCATAATCATTTGTGAAAGTTACAGATCCCAACTTCTCAAAAAAGTCGGAAATCTGTGACTGTCAATGAAAATTCCTTCTTCACTATTTAGCAATTATTTTGAGCGTTTTAGGAACTTTTCTGCTAGGTAAAGTCAAACCTAAAAATAGGAATTATCGTCCGGCGTACCGTTCCATTTTGCAATATTAAATACAGGTGTTCCATCGACTAGAATATACAGAGGGAAATCTCCTTGTGTTGTATTGCCATCCCAATTCCAGTCAGTAGAGTAAATGTGTTCTCCATGACCATTGTTGCCTGCATGGTTAATTGTCGGGCCGCTACCTGTCAAATTGATGGATAACGAATCACCGTAGCCAATGGACATTGAAGAACCCCGACGCATACTTCCACCTCGGAATTGTCTAACATCCATCTCTTGACCCCTACTAGGCGGATCTAAGTTCGGGATTTGAGCTGCATCACTACTTAATTGCAGAGTTTCCTTGATAAAAGTTCCTCTAATATTGCTAAACCCAACTGCTCCAACAGTACCAATTGTATCTGCGGTGTGATCTCCACTGTCTGACCAAATAAATTCTACATTGTCTGTTGTTTTTTGGTTTGTATTAAGTAGTGTTTCAATCTGCAACTGAACTTCTGCCTTTACAGCTTCCAAAATGGCTAAATCCAAAGTGCCACCAGATTGATTAGGTGAATCTGATGCAGTTGGTGCTGGAGCTGCTGGAGTTGGGGTTGGAGCTGGGGTTGGGGTTGGAGCTGGGGTTGGAGCTGGGGCAGTTCCTTGAGTCGGTGGAGCTAGGGGTACATCAGGATGCTGTCGTTTCCAGTGACTCACATAGGCATTAATTAGACGATATTGGGTAATCAACTGTAGTTTTTGTTTGTCTACAGGTGACATATATCCATTATCTAGTTGAACGCTTTGAACACCGCTTTGTCCAGGAGCAAGCGCACCTCCTACCTGTGCAGCAGCTTGTCCTGCTTGAATAGTTGCTGCTGCTATGGTTGCTGCTGCTGCTCCTGATTCAGTTGCCAGACTAGCACCCCAAGCACCGATCGCACCAATTACTGGTAGAGCATTTTGTACAATTGGCTTTTGCTGAACTGCCTTGCTTACAGTTCCGTCTATTTTCTTGGCTTGAATAGACTCTTTCGTGATTGCATCAGGGCTTGCTGCTGCCTTATTACCTAGTACATCAGCTTCTGCTTCCAAAGCTTGGTCTTGCACAACTATGGAATTCCCTTCTCCAGGTAGTTTTGGGATATTAACCCGTCCCTGTCGTTGTTGTACTACATGGCTTAATTCATGTCCAATTAGAGCTTGACCAGATTGACTTTCTGGATCGTACTTTCCCTGAGCAAAATGTAAATTATTACCAGATGCGAAAGCCTGAGAACCTAGCTTTTCTGCTTGACCATCCGTATGAATTTTTACATCTGATAAATCTGCATTAAATGCTGTCTGCATCTTTGCTAGGACAGGTTCTGGAAGATTTTGTCCACCACTAGGAGTCACAACATCGGCTCCATAAGAGGCGTTTTTTATACCACTTCCCTGAATAACTGCATTTTCTAATCTATTAATCACGCCTTCGGTGAATGCTTTTTGTGGACGCAATGACATACGACTAATGTCATGACTCAGAGGCGATTGTTTGATTGGTTCAGATTTTACTCCTTGCTCATCAGCAGACTGCACCTCTTGAAGGTCTGTTGATGACTTACTTATTGTTTGGGAGCCAAAGCCGCGTATCGGGTTCGCCAGCGTTGGAATACTTGGTGAGGCAAGGGATGGATTCAGAAAAGTGGATGTATTTGCTTTCTGATGTCCAGCCGTACCGGGACGCAAAGTGGCTTGTCTTTGGACATTGCTCATCTCATCTTTCCTCCATCAATAGCCTAACTACAGCATAATGCTAAGACACAGGATACAATTTGTCTGTATCAAATCCTTATGGACTTTAGTATAAATTTCCGATTCTATACTTGATATCAATCCTGTCCATATCCATTGCCTTCCCTCATTCTCAAGTATATTTTTGAGTCAAATCATACAATTTAATGATTGCGATCACCTAGTGTGCCGTAGGCAATCGCTATGGACTTAAGTGGAAAGTATTCTGTAATGCGATCGCTCATCTCACTTTTAGCTATACTAAGTACGACAAAAATTACTTAAAACTTTGTGATTGTGCCACAAAGTTGGTTTCATTATCGATAATAAAAGTAACCCTTCAGCAATTTCCCATTGTACTCTATTAGTAAATCGTAACAATATTTTAACTATGACTACGCAAACACTACCTCCACCAGAAGTTTATCAAGGTCAGTTTGGGGAATTTACAATTACTCAGAGCGATCGCACTGGCGTAATTATCTACCGTGCTGGCTTAATGGTAGCAGCAGTCAGCTTTGCGATAGGCAGCGCTTTGATTTTGTTCAACAATAACCCGACTGTTGTAACTGCACTTACACCTTTATATGCTTGTTTTAGTCTCGCTCTTGGTGTAAGTTTATTTACCATTCATATCTACATGGCATCACTGCATCGAATGTTGCAAATTTTTTGGGCGATCGGTAGTATGGCATCAGTTATTCTGGCAATTTCTAGTACTGAACCTTTAGCTCTGACTGTTTACAATCAGCCTCTTACCTTATTTGGGGTTGGTTTTATTTTTGTTGCTTTGACAGGGATTTATTTTAAAGAGGCTTTTTGCTTCAATCGTTTAGAAACTAAAGTATTAACCCTAATAGTACCGCTACTGTTATTAGGACATTTGGTGGGAATTTTACCAACTCAGGGCGAAAGTGTTTTATTAGGAATTTGGGCAACGTTGTTTTTGGTATTTGCCCTGCGAAAGACAGTGCAAGCAATTCCTGCTGATATTGGAGATAAATCTGTATTTACTTACTTGGAAGAACAACGTCTAGCTAAAATTTAATGCAGGCAAAAAACCGTCGGCGTAAAAATTTTCCAAAAATCAAACTAATAAAACGCCAAGAAATGTGGACACTTACGGCTCAGGGGTGGGCGATTGCGATCGCTTTGATTGCTTATTTAATATTTTTCGTTATTACTCATGTACACTCATTTCTCGCCGTGACTTCCCCGATCAAATCAGCAGAAGTATTAGTTGTTGAAGGATGGCTACCAGATTATGCCATACAACAAGCTTTAACTGAATTTAAAAACGGTTCTTATAATCTAGTAATTACTACAGGAGGATCGATAGAAAAAGGAAATTATCTTAGCGAATACAAAAGCTTTGCAGAAGTATCAGCCGCTACCTTCGAGAAACTCGGTTTAGAATCGGAGAAGGTAGTAGCTGTTCCGACACCAAACGTAATCAAGGATCGTAGTTATGCCTCTGCTGCTGAATTTGATCGCTGGCTATCCGATTCCAATTTAAAGCTAAAATCAATTAATGTTTTTTCTTTGGATGTTCACACCCGTAGAAGTTGGTTCCTATTCAGAAAAATACTTACACCTCAAGTCCAAGTTGGTGCGATCGCAGCTAGAACTCATGATTACGATCCAAACAAATGGTGGGTTTCTAGCCAAGGTGTGCGGACAATTCTTGATGAAGGCATCGCTTATATTTACGCGCGATTTTTGAATTGGAAAGCCTAAAGGTGATAATTCGTAATTCGTAATTCGTAATTTCGAGTTACGAACTACGAATTATGTTTAGATAAACGTAACTTTGGTAGGTGGTTTTACTATGGAAAATTAGACGACATTATATTATTTTTCCAGGATTTGTAATAATGCTTGTCGATAAATTTTTAGACCCTCAGCATTGAGATGGTCGCCATCACTCGTCAAATTCTCTTTAAGAACATTATTCTCATACAATGGTGCTAGCCCTGCTGCTGCAACTGGCACTTTTTCTTTTTCAGCGACTTGATTAATCAGAACATTAATTTGTTCAACTTTAGGAAGTGGGGCTGATACAGTTGGATCTAAGCTGGCTGCAACTGTTGAATAAAAAGCCGGAATCAGAAAAATCTCTTTATTTCCCATTGTTCTAACAAGTGCGATCGCTTCTTGGAGATTTTTGCTAAACAATTCATCACTAATTCCATACCAAGCATCATTCCCACCTACGGCAATAATAGCTTTTTCGCATTTAACTTTAGTAGGAATTAAACTTTTCAATTGTTCCAGTAAAGAGATTGTGCTTAAGCCATTTAACCCAAAATTAAAAGTGCCACTCCCAAGGGTATTACCAAGCCCCGCCGAAATAGAATCGCCAAATAAGCAACCTGAAAACTGTTTATCTTGGGCGGCGAGTATTTGATATTGCAGTGCAATTTTCCCAAAAGGTGAAGAACTTACATTATCTTTTGGTAGTGCATTAGCAGAATTAGAAGAGGAATTTGCTAGTCCAACTAGCTTAGAAATTTTTGACACATCAACAACTAGTTGATTACTAGGATATGCTTCTAAAAAGCTGATTAATCCTAGACCTTCTGGTGATTTTGCTCCGATGATGAGGGCAGAACGTAGGGCTTGTGTACTGGCTTGATCGCGACGAGCGATCGCACCAGAAGCAAAAGATAAAATTTGCTTGCCCATTCCTGTATTTATCAGCTTATCTAAAGCCACAATATCAAGCGACATTTTCACTTGAAGGGCTTCTTGAAACTTCTCTTTCTCTTTAGCGCTGAGGTAATCTAAGAAAGATTGCAAATCGCTAGAAGCCTTTTGTTTCTCGCCATAGTTGCGTATATCTGCCACCGGGATTGATTGCTCAAACAACCCGTATCTGACAGTAACTTTCTCGGCTGCCAAACTAGGCAATAAACCAAGACCACTATGCACCAGTAAAAATATTAAGCACCCAGATAGGCTTATTAAAAGACGATAAAAATATTTCATCACAGAAGATCAGAAGATAGATAGTCAATAGTTAATAGTCAAGAGTCAAGAGTCAAAAGTCAAGGGGTTAGTCATTTGTCATTAATTCTTCCCCTGCTCCCTCATCCCCCTCAACAGCCAAGCCCAATTTGGGAATACTCAATCCAGTGGCATGAGGACAGAACGGTGGTGGAAGAAGGCGCATATTGGATAGCTTGGGCGCAAATTTCGGGAATTGGCCCGGTATTATTGCGACGGCTGCAACAGCATTTTGGCACGCTGGCAACAGCTTGGAACGCTACCAAGGTAGAGTTAGGAGAAGTGGAGGGTTTTGGTTTTCAGACACTAGAAAAAGTAGTACAACAGCGATCGCGTTTGCACCCAGAACAACTATTCACCAAGCATCAGCAGGAAAATTCCCATTTCTGGACACCAGCAGATGCAGATTATCCCCGCTTACTGCTGGAAACTCCCAGTCCACCGCCGATTTTGTACTATCGCGGTGAAGTTGAACTTCAAGAAAATCTCGGACAAAAACCGATGGTTGGTATTGTCGGCACACGCCAACCTTCAGAATATGGCATCCGTTGGACTCGCCAAATTAGTACAGCTTTAGCTAAAAATGGCTTTACAGTTGTTTCTGGGATGGCAGAGGGAATTGACACAGAAAGCCACAGTGCTGCAATGAAAGCAGGTGGACGCACGATCGCAGTTTTGGGAACTGGTGTAGATGTGATCTATCCACATAAAAATCGGGATTTGTACAAGCAAATTTTGACGGCTGGTTTAGTTGTGAGTGAGTACCCCACAAAAACCCCACCCGATCGCACGCACTTTCCCCGCCGCAACCGGATTATTGCAGGTTTAAGCCGCGCTATCTTGGTAATGGAAGCGCCATTAAAATCTGGTGCGTTAATTACTGCTACATACGCAAATGAATTTGGCAGAGATGTCTATGCCTTACCTGGAAGAGTGGACGATCATCCATCTCAAGGATGCTTAAAGTTACTGAGTCAGGGAGCTTCTTTGATTGTCAAGGAATTGGATGAATTGTTAACAATGCTGGGAGCAATACCACAAATTGATGGAGTCGAGGCTTCCACAGCGCCAGAAAAGTTAATGCCAACTTTATCGCCAGAATTGCAAACGGTAATGGATGCGTTTACAAGTGATGCTTTACCCTTTGATTTTATTGTCCAACAAAGCGGCATGGCTGCTGGCTCAGTTTCGGGTGCTTTGTTGCAGTTGGAACTTATAGGTTTAGTTTCGCAATTACCAGGGATGCGGTATCAAAAAAGTTAAGAGTTAAAATTTCCTAATTTTGTCCACACCCAACCTTTAGGCAATTCTATTAATTTAAATTTAACTTCTTCCTCTGTGTCCTCTGTGCCTCTGCGGTTTATAAATCATTTATTTAACCACAGAGGCGCAGAGAACTATAGAGATAAGTATCATGGTTTCCTGCCGCATCAGCAATGCCGAAGTCTAATGACCAATAACTAATCAATTCATAAGTTCATAAGAACAATTGTTGCAATGATTTAAACGTTTCTTATACATGGAAGAGTATTTGTTGCAAAGTATTAAGCATTTGCTACAACTGATTATACCTTTGCAAGAAATACTTAAGCGTTTCTTATATATGGAAGAATATTTGTTGCAAACGTTTGAATTTTGACAATTAGTGTTTGAATTTGAGCAATGACTATTTGGTTGATAGTTTCGGGTATAGCAATCCTATTTGATTTGCAAACAGAAATTGTCACTTCAATTGCGATCGCCAGTCTCTACGGACTATACTTTGTGGTTTTAATTCAGTGCAACGCCTGCATACCGCTAGTTCTCCCAGCCCCGTATGTTATCCAACGATACGCCCACCTACTTATCTTTGAGGGTAATACTGAGGATTCATAACTGGAGACTGATAACCATTTGCCGGTACAGTACTTCCCATCCCATTAGGTACAGGACTGATAACAGGGGGCTGATAACCACTCATAGGTACAGTACCTGTCGTACTGTTGGGTAAAGCAGGATTCCCAATTTGGGGCTGATAACCATTTGCGGGTATAGTGCTTGTGGTACTGTTGGGTGTAACAGCATTTTGGCTAAACTCTTGGTAGGCAGCACGAGAAATTGAGCTAATCAGTTTTTCGGCGCGAGGGTCGTTTTCGGGGCGTTGTACCATGACGGTAGCTATATAGCGCTTGCCAGTGGGAACAACAATTAAACCTGTATCTGCCAGCATAGTCCCGATATCGCCCGTTTTATGGAATGCTCTTGCGCCTGTTCCCAAACCCGATGGTAGTAGAGTGTCCCTTTGGGTGCGACGCAAGATATCGAGCATGAGATCGCGTGATGGCATACTGACTAAATTTCCCTGACTCACAATAGCCATCAAATTCGACAATTCTTTGGGACTAGTAGTATTTGTCCCTTGCAAATCTGGCAAAATATTACGAATTGTTGTGGTTGTCAATCCCCAAGTGCGGAAACGCTGGTTTAACGCCTCCATCCCTCCTAGCCGAGCAATCAGCATATTTGTCGCCGTGTTATCGCTGATTGTAATCATTTTAGTGACGACTTCCAGGGCATTGTACTTGGTTCCGGCTGGTTTTGACCCCATATCTCCAGAACCGCCAGCTACCATATCCTGTTGCATGGTCAGCATTTCATCAAGGCGAATTTTCCCCGCATCCACATCCTGGAAAAAGGCAAGTAGAATCGGCACTTTAATTGTGCTAGCTGCTGGAAAACTGGTAGAGCCGTTAACATCCACGTAATTACCAGTGTCCAAATCTACCAAGAAAACACCGGGTGCAAGATTTGGGTAGTTCGCTGCCAAATTTTGCACGGCATTTTTCAAAGAGATAATTTCCTGAGATAGATATAAGCTCGAAGATGCAGTTGGGGGAGCTTGGGTAGATTGTGGCTGCGATCGCGCCACATTACTATTAGATTGAGGTGTAGAAGTTGTACTAATGCGATTAGCCGGGTCTAATACTGACAACACCGTGCCCACAATTGCACCCATTCCAACACCCACTATCAACAAGCGCACAACATACAACATAGTTTTGGCCATTGGCTTTAATCGCGTTTTCCGCGATGAACGCAGGCCTCTTTTTGGCTTTTCCATCCGCACTGTTTTCACCATTACAGCACCTGGTCGAAAGGGAGGAATTTTCCCCTTTACAGTTGGTATTGGTTTTACTGCCGTTGGCATGACTAATCCCGATTTTACCCTACGTGTAGCACTAGGGGTTGGGGGGGGAGCAACGCGATTTTTGGAGCGTGCTAGCGCCGCTTCTCGTCCATTGGCAGCTTGCTGCTGGCTATTAGCTTTAACTTTCTTTTGCGCCACTTTTTGAACTTTTTGTGGACGTTGGCGGCGATTTAGGGGTTGTCGCCGCGAGAAAGCTGTTAGTTCGTCACTTGACTCTGACACAGTTACTCCTTGTGACCGACTTGACTGTTTTCTTGCAGACTCCTGACCCAAAACTTAATCTTTAAGCAATATTAATACTCAAATTCCACTTTGCCACTAAGTAGCATTTTTGTGTTTAGTTTAAGCCATATTAAATATTTGGGGGGGTGATTGCGTATATATTAAACGAATAATTATAAGTTTTCACCATCCCCCTGGTTTTTCAAAGCCCATTCTACCTGCTGCAAAATTCCTCGCAGCATAGCTACTTCCCTAGTTTTCAGGTGAGCGCGATTATATAGTTGGCGAAATTTTCCCATGCGACTAGCTGCTGTATGGGGATATACATAACCAATTTTCAGTAATAGTGATTCTAATTGTTGGTAGTATCCCTCTAAAACATCTAAGGGTGCGAGTTCAGTTTGGGTTATGGTCTGAGTGTCAAATTGTTGGGCAGATTGTGACAATTCATAACAACAGATTGCCACAGCAGTAGCTAAATTCAAGGCTACATAATCTTGACTAGTGGGAATACCAACAAACCTCTGGGCATAATTTAATTCTTCATTGCTTAATCCCCGGTCTTCCCTGCCAAAAATCAGCGCTGTGGGCTTTTCTGGTTCCTCTAGTAACCAGGGTAGTGCAGTGCGGGGGTTTTCTAAAGGTGTTTCTAAACTGCGAACGCGACCGGTTGTAGCGATCGCTCGTACACATCCATGCAATGCTTCTGGTAGGGTTGCCACTAATACGGCAGATTCTATAATTTCCTGAGCGTGAACAGCCATCATCAAAGCTTCCGTCGAGAGCGGATCGCATTGGGGGTTCACTAATACTAAATTATATAACCCGAAATTTTTCATTACCCTGGCGATCGCCCCGATATTTATCGGCCCAGCTGGTTCTACCAACACAATTCTTAATCCAGCCAAGCCCATTTTTTGCCTCCTGCAATCGCACCATAAAATATTTTTAGGCTAACTCTCAGCGTTGTAGTTCTGCTGAAGAGTTTTCTTGAAATCATTTTACCTGTTTGACGCACTCACCCCTAGAAAGGATGGAATTCAACCACTTATATGAGATGCTGATTGATGATTAGTGAGTTTTACCAATGTCTGTTGTTTCTGCCATCACTGTTACTGTTCCCGCCACAACTGCTAATTTGGGGCCTGGTTTTGATTGCATCGGTGCAGCTTTAAAGCTGTACAACGAGTTCAAATTTACTCGCCTAGAAGAAGGTGGGCTAATTATTCATGTCACTGGTACGGAAGCTGAACGAGTCCAAACTGATGAAAGCAATCTCCTTTACCAAGCGTTTGTCAAATTCTATCAACATATAGAGCAAACGCCGCCAACTGTGAAAATAGAGATTAAGTTAGGTGTCCCACTGGCGAGGGGTTTGGGTAGTTCGGCGACAGCGATTGTGGGCGGATTAGTTGCTGCAAATCAACTTGAGGGTGCTACTCTTTCTCAGTCGCAGGTGATGGAGTTAGCGATCGCAATGGAAGGACATCCTGATAATATAGTGCCAGCTTTGCTGGGAGGGTGTCGTCTGGCTGCTACCAGTGGCACAGCTTGGGAAATTTGTGATGTTCCCTGGCATAAAGATGTTGTACCAGTTGTAGGTATTCCTAATTTTGAACTTTCCACTTCAGAGGCGCGGGGCGTTTTGCCAACTGAGGTGAGTCGCGCTGATGCAATTTTCAATACGGCACATTTGGGGTTACTGTTGCGCGGCTTGGAAACTGGTAACGGACAATGGTTAAAAACAGCTTTGCAAGATAAATTGCATCAGCCCTATCGCAAAGCTTTGATTCCTGGTTATGATGCTGTCAACATCGCAGCTGTTAGTGCTGGTGCTTATGGTATGGTAATTAGTGGTGCGGGGCCGACACTGTTAGCTTTGGCGGATAAATTACACTCAAAGGCTGTGGAGGCGGCGATGTTAGCTGCTTGGCAAGAAGAAGGAATTACAGCCGAGGTGCGATCGCTTTCTCTCGATACCCAAGGCGCAAAAAGCTTTTAAGATTTTATTCAGCACTTAAAACTCAGCACTTAAAACTCGATTTATGGAGCAAATTCAGGCTGAAATGGCGGCGCTTAACTCTCAAATTGAAATTCTTTTAGAAGAACGCGCTGCACTCACTATTAATAATGTCATCTCTAGCGAGAATGATTCACCCCAGGCAATGGTTGAAGCATATCGCCGTCAAGCCAGGGAAAATGCCCAATTATCAGTTGAACTCCAGGGCATTGATGCTGCGATCGCAGCTTTGGAATTCCAGATCAAACAAAAACAAGGTAAGTTAGTGCGATCGCAAGTTGCATCAAAACAACTTATCCAACAGCAGGAGTTAGAAGAAGCGAAAGAAGTGGCACAGGTTCATGCTCAACGCATTAATCAACTGGCTGGGGAATTGGCGGCAGAAGTCCGTTTTCTTAAAGCTTGTGCCAATGAACTGAGTCCAATGTATTGGCAGATTTATTACAAGCCTTTCATTACTGGGTTCAAAACAATCTCCGTTCCTTATGTCCGCTCTGATTTAGAAGTGTGGACAATTGTCAACCGGATTGTTTAATTCTGTGAACAACAGCATTAAGCGAAAACACCTCTAATTTGCATAACCAAATTTCATCAAACTTTTGTGGTTTATACCAATTTAATATGAAGTTGCACATATCTTGATGCCCCTAAATCCCCCTTAAAAAGAGGGACTTTGATAGATGTTTTTCCGGTTCCCCCCTTTATTAAGCTACCGTGTACACACAAATCATCTGATCCCCCTAAATCCCCCTTAAAAAGGGGGACTTGAAGAAATTTCCCCCCTTTTTAAGGGCAGGGCTGATTCATTCCACAAGGGCAAGGAGTTTGTCAATATCATGAGATAGAAATCTGTGAGCAATTGTTATAGAAGCATAACTATTGCGGCGAATGATGTTGAGTGCGATTGCTCTGGTAATGGAAAGATTTGCCGGAGCATTACCCATACGGATTGTGGAACTATCTTCTTTGAAAACAACATCTTTCACCCAGTGGAGGCGATTTTCGATACCCCAATGACCGCGAATACCGATAGCAAATTCTTTAGCTGTACCGAGCAGACTGCTAATATAACAGACAATTTCGTGATATTTTTTGCCTTTTCTTGTTCCAACTCTTTCCACTCTAATTAAAGAGTTTATCCCTATCCATTTTGGATCAATTCCCTTGATCTCATGGAATACTTCTACAGTACGTGTTGTCAATCTATCTCTAATTTTCTCTGTCTCAACTATACGACTTGTTGGTTTTCTCAGAGCAGCAATGCGTTGAATATGGCTATGTAGTTTTGGCTGATTATTTTTAACTGCAATGACGTAATCGTTACAACTTTTTATAATCATCTCACAAGTTTTTTTTGGCAATGTAAGGAATCAAAGCTGAAAACCACACCTTGTAGATCCATTGCTGTAATTAAATCTTGTACAACCTGGATTTCGCTTTTATCATGGTTTTCAAATTTTTTCATCCCGACGACCAGCCCTCTTTTACAAGCAAATACTGATACTATGCTGACAAAATTTTGCTGAGATGAATTGTAGTCTTTCACCGTCCCCTTAATACTTTTCCCATCCATAGCACACCATTCTAATTCTTCTATTTCAACATAACTTTTAGCCCAATCATTGAATTTTTCCGCCAGCTTATCAAACTCTACTCCCATCACTACACGTCGGATAGTTGAATAAGATGGAACTCCATGTTTTTGGATACCAAATTTCTTTATTAATACCCGACTATGCCTATTCACAAAATCTCCCCACCCACGATATCCCACATATCCATTCATAGTGCCCATTATTACAAACAATAAAACCAACCAAAGTGGATGTCTTCGACCATCTTTTGTCCTAAAGTCTTCCACTTGCTTTAACTGTTCGATTAGATTCGCACCCAT

Protein sequences of DBSCAN-SWA_3

>NZ_CP046703|1291643:1327239|1312871_1314851_-|WP_114086215.1|DBSCAN-SWA
MSNDGQQASGHLRIVQRQKAGISTVLNPSLALSTIPTLASPMRGFGLQTNNPPIQRLTEASTELQEVQSANEQFLEPEAVKQPLSHDISRISLHRPQAKLTVGAPDDHYEQEADQVADQVMRMAEPEPIGLQNTQTQDQVQTKPLASAITPLVQREAMPEEEEELQTKLINAPIQREILPEEELQTKRSLQLATNDSFQTGDNFESRLNSSEGGGSPLPDAVRSFMEPRFGTDFSQVRVHTGTQSVQMNQDLNAQAFTHQQNIFFGAGKSPGNDALTAHELTHVVQQTGTAQRKLIQRAINPTYDLTHGIFEVNATPNGASLPITIRFKPKTTAPYSNQIGLIQIVRLTNATGTNVEPQSLPAASGASLRTTADATTGVEGGYFTDALHNDAPAHGGTGTNAAAGSALPAQYPFGNDPAQPNPATPGLSRPSSSGASGATIGYKRSDDPTDIKAAELTDAPGGAGEFNFDFQTVAKGEDTMTTYGALHWGFQIRAGKVENDHASAQDGQSATFDAALQKHQDFYVHEPVIFYFDFDSDQLSSSETGKIDTFLDYLRRFPDVKVTPEGFADRRGGASQHNLDLSLRRAQAVGAALRAKGVAEAQISAVTIGSGSTEDFTPDATTNQDTEANRRGNRRVVLSFQHVPAAAPAAPAGGGGTP
>NZ_CP046703|1291643:1327239|1311514_1312051_+|WP_114086213.1|DBSCAN-SWA
MLQHLITQQYYFALKLFSALGCGLIAGVFFAFSTFVMNALARLKPPQGITAMQSINITVINPFFMTAFLGTAAACIFLLISSLLKWHQPGAAYLLLGSLLYLVGTLGVTIVFNVPLNEALAKVEPDSTEGASLWSSYLTNWTIWNHIRTVAALAAATSLTIALCLGSRIVEGIDNTVR
>NZ_CP046703|1291643:1327239|1303876_1304914_+|WP_114080551.1|DBSCAN-SWA
MKILDRNLTKPFKTIFTEHRVLWAVLLLSAALVITLALSLSQGAVPLSMSEFWQAILRKGDPVKQTIFWDLRLPRITAALIVGAALGMSGALLQGMLRNSLADPFILGISAGAGLVVIVMIVWQIFPIAIPLAAWIGAILTSAIVILLGRAGSGISVERLILGGVAVSSLFGAVQSTLLLLAEDGQIQIALSWLVGSLNGRGWQEISTAGPYIIVALIGGCLLARSVNVLALGDDLAVGLGVSLTRSRLLIGGVATLLAAGAVSISGLIGFVGLVVPHGVRLIVGTDHRFVLPLSALAGAWLLTFADLLSRLGAVELPVGSVTALLGSPLFIWLLYRRSAGFNKF
>NZ_CP046703|1291643:1327239|1309950_1310661_-|WP_114086212.1|DBSCAN-SWA
MVMKSLKEHQLYGHLAVEKKLGILVVDDHQLILTGTLDVLNRKYPEAIIIKAQTAKDTLSQVQCYQFDLIVMDLSIPDRQGETAEIDTGIKLLQTLLKEYPHQNFIVQTSYVKALIRIKHEIDNHQGGFAIADKGLPEDEMLMRVNLALQGATHTKDIKTGIELKPEWLDVLRLAFEESLTDKAIADRMYKSERAVCTYWTKIQDVLGVYPEDCKQSGKNMRILTEIRSREEGLID
>NZ_CP046703|1291643:1327239|1323498_1324239_-|WP_114086222.1|DBSCAN-SWA
MGLAGLRIVLVEPAGPINIGAIARVMKNFGLYNLVLVNPQCDPLSTEALMMAVHAQEIIESAVLVATLPEALHGCVRAIATTGRVRSLETPLENPRTALPWLLEEPEKPTALIFGREDRGLSNEELNYAQRFVGIPTSQDYVALNLATAVAICCYELSQSAQQFDTQTITQTELAPLDVLEGYYQQLESLLLKIGYVYPHTAASRMGKFRQLYNRAHLKTREVAMLRGILQQVEWALKNQGDGENL
>NZ_CP046703|1291643:1327239|1325370_1325880_+|WP_114086224.1|DBSCAN-SWA
MEQIQAEMAALNSQIEILLEERAALTINNVISSENDSPQAMVEAYRRQARENAQLSVELQGIDAAIAALEFQIKQKQGKLVRSQVASKQLIQQQELEEAKEVAQVHAQRINQLAGELAAEVRFLKACANELSPMYWQIYYKPFITGFKTISVPYVRSDLEVWTIVNRIV
>NZ_CP046703|1291643:1327239|1294948_1297588_-|WP_114080558.1|DBSCAN-SWA
MSLPILNQRFRTWWQPRRGLAIAEACVIGLVAALSAVFLKVGSGWLGTWRVHTTHLFPAWLVLPVIGLVLGFLAGWMVDRLAPEAAGSGIPQVKASLANVPVNLSWRVAGVKLLSAIIAIGSGMTLGRQGPTVQVGAGLAAGMSRWVPTSPDHRRQMIAAGAGAGLAAAFNAPIAGVLFIVEELLQDLSGLTLGTAIIASFIGGVISRLLGGGSFDLNLQLTQSSSQFSIPEIPFFVLLGILAGLLGALFHSGLIFSIKFYRRLHISLPLRVALAGFISGVVVAMLPASFRDNTGLRESFITGDSQPTVAAIAFTAQFILTLIAFGSGAPGGLFAPSLILGSCLGHIIGVAELYITGVGSPTTYALAGMGGFFSAVSKVPITAIVIVFEMTTDFNLVLPLMIVSVAAYLVADKVVPGSLYEKLLELKGITLTKQLPMEGALTKLTAKDVMQERVETLDAEMSLEEAMQSFARSHHRGFPVVEDSKLVGIVTQSDLLKIRESAKHTLRDRNLADIFLKEIMTPVPMTVTPTHTLANVLYLLDRYQISRLPVVNGRKLIGIITRADIIRAEVDHLNCGNGTPKLQPEPSYIVYQTRSPSTGSGRLLVPVANPETAGILLQMAAAIARDRHYEIDCVQVMLIPRHSSPSETQVRTAKSRRLLRQAEVLAKKWKIPLHTQIRVTHDVAQAILETINEQHIDLILMGWKGNTSTPGRIFGSVVDNIIRQATCEVVLVKLGTTGHSLISSPQFNRWLVPMAGGPNSPLAIKLLPALITLGNEPQIHLTQVFKPFEFKPDMSISEQAIRHLMRRQKLSSTVVALPVQADSVAEGVINLVKTEGYDVVVLGASREGLLQQAIQGNIPEAIASGVESTVILVRGAIHK
>NZ_CP046703|1291643:1327239|1305421_1305742_-|WP_114080550.1|DBSCAN-SWA
MSTSWIYLIAAILFEVSGTTCMKLSEGFTKLVPSVLIFVFYGLCFSFLTLALKRLEVSVAYSVWAGLGTVLIAIIGIIWFRESATFIKLLSIALIIMGVIGINASE
>NZ_CP046703|1291643:1327239|1306167_1306737_-|WP_114081709.1|transposase|DBSCAN-SWA
MILNCLEKHLAPGKCVRYLCQDETRVGLKTLTGKVITASGVKPTVEVKWPRENFWIYGAIEPLTGDHFLYEYPKLNGECFQQFLDWLSQQLGGDYAILQVDQAPAHTSSAIRWPENIIPLFQPPSAPELNPIERLWQLLKKPLKNQLFSSLQNLRDRIQEIFNQLTLEQVISISSYNFILEALFYAASY
>NZ_CP046703|1291643:1327239|1324412_1325327_+|WP_114086223.1|DBSCAN-SWA
MSVVSAITVTVPATTANLGPGFDCIGAALKLYNEFKFTRLEEGGLIIHVTGTEAERVQTDESNLLYQAFVKFYQHIEQTPPTVKIEIKLGVPLARGLGSSATAIVGGLVAANQLEGATLSQSQVMELAIAMEGHPDNIVPALLGGCRLAATSGTAWEICDVPWHKDVVPVVGIPNFELSTSEARGVLPTEVSRADAIFNTAHLGLLLRGLETGNGQWLKTALQDKLHQPYRKALIPGYDAVNIAAVSAGAYGMVISGAGPTLLALADKLHSKAVEAAMLAAWQEEGITAEVRSLSLDTQGAKSF
>NZ_CP046703|1291643:1327239|1326148_1326685_-|WP_159402451.1|transposase|DBSCAN-SWA
MIIKSCNDYVIAVKNNQPKLHSHIQRIAALRKPTSRIVETEKIRDRLTTRTVEVFHEIKGIDPKWIGINSLIRVERVGTRKGKKYHEIVCYISSLLGTAKEFAIGIRGHWGIENRLHWVKDVVFKEDSSTIRMGNAPANLSITRAIALNIIRRNSYASITIAHRFLSHDIDKLLALVE
>NZ_CP046703|1291643:1327239|1300598_1301243_-|WP_114080555.1|DBSCAN-SWA
MEQPKVIFLDAVGTLFDVKGSVGKVYSQIAEEFGVTVPAETLNTAFIKSFKAAPPPIFPDAELQDIPQREFDWWRIIALNTFESAGVLKEFSDFSAFFSELYIHFGTGEPWFVYPDVLPALINWRRLGVTLGVLSNFDSRIYSVLQSLGLREFFTSVTIATQVRAAKPDPQIFAIALDKHKCSPSAAWHIGDSVVEDYYAAKAAGLRGVWINRG
>NZ_CP046703|1291643:1327239|1291643_1292866_-|WP_159402613.1|transposase|DBSCAN-SWA
MQLTDSLKKLLKETAHQLKGAAKRRFIAQTVVALGHGGKSIAERELGWNRVTIGKGIKELNSGITCVDNYQGRGRKKAEEHLPTLLEDIKKLVDSQSQIDPTFKSQRLYTRLGASVVRHQLIEKFGYAEEELPTSETIRVKLNDLGYRLKRVAKIQPQKKFPETDAIFEQLAIVHQEASDDPTILRLSLDAKARVNIGSFDRGGRNRVPTETDDHDFKPKTTVAPYGIFLPDLDELFLYFTESKVTSDFIVDILGDFWKSESWRFSEIKTLLINQDNGGENSSRRTQFMKRIVEFAQSYKLNIRLAYYPPYHSKYNPIERTWAVLENHWNGSILDDVETALNFAKTMTWNGKSPVVKLVTQTYSSGVRLTKKAMQEIENKIERLTNFTEDNLPNLGKWFIDICCGVT
>NZ_CP046703|1291643:1327239|1306727_1307228_-|WP_114081708.1|DBSCAN-SWA
MSRPFEIEIAESEEELKKRLQTANLGNQKEKLIMLWWIKSGQAKEQQDIGKRLAKDTSTVTRWLQKYRSGGLDELLKIKKAPGAKRKIPEGAITALEEELKTGKGFSSYGAIVEWLKQEQGLDIEYATVYALVRYRLGAKLKVPRPQSHKQDEKLVSEFKKNSVSF
>NZ_CP046703|1291643:1327239|1293506_1294064_+|WP_114081705.1|transposase|DBSCAN-SWA
MGANLIEQLKQVEDFRTKDGRRHPLWLVLLFVIMGTMNGYVGYRGWGDFVNRHSRVLIKKFGIQKHGVPSYSTIRRVVMGVEFDKLAEKFNDWAKSYVEIEELEWCAMDGKSIKGTVKDYNSSQQNFVSIVSVFACKRGLVVGMKKFENHDKSEIQVVQDLITAMDLQGVVFSFDSLHCQKKLVR
>NZ_CP046703|1291643:1327239|1299104_1299272_+|WP_159402452.1|DBSCAN-SWA
MTLSELWILNRISTHLGESAIAKNQRSGFLPMDADNYPKIISVSLQLRFGTADQN
>NZ_CP046703|1291643:1327239|1318761_1319898_-|WP_114086219.1|DBSCAN-SWA
MKYFYRLLISLSGCLIFLLVHSGLGLLPSLAAEKVTVRYGLFEQSIPVADIRNYGEKQKASSDLQSFLDYLSAKEKEKFQEALQVKMSLDIVALDKLINTGMGKQILSFASGAIARRDQASTQALRSALIIGAKSPEGLGLISFLEAYPSNQLVVDVSKISKLVGLANSSSNSANALPKDNVSSSPFGKIALQYQILAAQDKQFSGCLFGDSISAGLGNTLGSGTFNFGLNGLSTISLLEQLKSLIPTKVKCEKAIIAVGGNDAWYGISDELFSKNLQEAIALVRTMGNKEIFLIPAFYSTVAASLDPTVSAPLPKVEQINVLINQVAEKEKVPVAAAGLAPLYENNVLKENLTSDGDHLNAEGLKIYRQALLQILEK
>NZ_CP046703|1291643:1327239|1307383_1307833_+|WP_114086208.1|DBSCAN-SWA
MTLVRLNPWQELNTIQRQINRLFDEETLPSAFLDRGYARVPAAELKETEDAIHLKVELPGIEAKDLDLQVTENAVYLSGERKSEAKSEEKGVIKSEFHYGKFQRVIPLPTRIQNTNVKADYKDGILNLTLPKAEEEKNKVVKVNLASSG
>NZ_CP046703|1291643:1327239|1294700_1294895_+|WP_114080559.1|DBSCAN-SWA
MEDSVFIIFLSFGFLWVLMGVVGWIAFLKSEGEEIKFGKWGLIVAIPILIPIIFTLIIGVLYYR
>NZ_CP046703|1291643:1327239|1302833_1303457_+|WP_114080553.1|DBSCAN-SWA
MEIKPTDPSLALKEIPPGYLNIMGYVDQSEVNGPGCRAVVWVQGCLRECPGCFNTNSWSFEANQLIAVDTLAENILSNPHNTGVTFSGGEPFWQATALASLARKVKAAGLNVMSFSGFTLKQLQSQSAPPGSQELLEQLDILIDGPFVQSLAINSPNSPVSSSNQRVRVLNPAFQDQITWASDQIEVHILKDGGRIVTGYQGGLELT
>NZ_CP046703|1291643:1327239|1297792_1299106_-|WP_114080557.1|DBSCAN-SWA
MGSENLSQDTLAEQLLELAIKSGAEAAEVYQSRSLSRPVFFEANRLKQLETNQSEGTALRLWRNGRPGLTVAYGSVLAEVMVEKALALSHLNEPETVELGSNFQPSYPDLGESVPIEILVDWGKEAIALIRDVYPDVVCNGDWECDIETTRIVNTKGLDCYYTDTTLNCYVSAEWVRGDDFLSVADGQTKRGELHPERLANQILQRLIWARENVSPPTGRVPILFTSKAADMLWGTVQAALNGKQVLEVSSPWAERLGNPVVAPSLTLYQDPEAGPYSCPFDDEGTPTQSLVFIQNGILQHFYGDRTTGRQLGTDTTGNGFRPGLGSYPTPGLFNFLIQPGSASLPDLIQQLDDGLIVDQMLGDGGSISGDFSINVDLGYRVQNGQVIGRVKDTMVAGNVYTALKQLVALGNDGDWNGSCYTPSLIVEGLSTTGRSN
>NZ_CP046703|1291643:1327239|1294060_1294597_+|WP_159402451.1|transposase|DBSCAN-SWA
MIIKSCNDYVIAVKNNQPKLHSHIQRIAALRKPTSRIVETEKIRDRLTTRTVEVFHEIKGIDPKWIGINSLIRVERVGTRKGKKYHEIVCYISSLLGTAKEFAIGIRGHWGIENRLHWVKDVVFKEDSSTIRMGNAPANLSITRAIALNIIRRNSYASITIAHRFLSHDIDKLLALVE
>NZ_CP046703|1291643:1327239|1321578_1321791_+|WP_147262609.1|DBSCAN-SWA
MTIWLIVSGIAILFDLQTEIVTSIAIASLYGLYFVVLIQCNACIPLVLPAPYVIQRYAHLLIFEGNTEDS
>NZ_CP046703|1291643:1327239|1312197_1312809_-|WP_159402454.1|DBSCAN-SWA
MNNQDATATPMEQIKTRLYSTDQDTSALALGELIRLGKKATPVLLEALTNPNPRTRRLAAEGLSEIADPASADALFQATHDTNPEVRARAATALHQLGDKRSLSALVATLDDYPDILHNPYTASMYPLMRGGKEVLPLVIPLLQAPNDLTRERAFLIVKAVVSKLPQGQDWNQLWQSLGSYDPAGQKAERDKAAQKWQEWLSK
>NZ_CP046703|1291643:1327239|1308074_1308374_-|WP_114086209.1|DBSCAN-SWA
MATYKVTLKTPDEEKTIEVSEDDYILEIANEENDMDLPYSCNAGSCSTCAGKLVSGTVDQSDQNFLDDDQIDAGWVLTCVAKPTSDCVILTNQEDELNG
>NZ_CP046703|1291643:1327239|1317957_1318647_+|WP_114086218.1|DBSCAN-SWA
MQAKNRRRKNFPKIKLIKRQEMWTLTAQGWAIAIALIAYLIFFVITHVHSFLAVTSPIKSAEVLVVEGWLPDYAIQQALTEFKNGSYNLVITTGGSIEKGNYLSEYKSFAEVSAATFEKLGLESEKVVAVPTPNVIKDRSYASAAEFDRWLSDSNLKLKSINVFSLDVHTRRSWFLFRKILTPQVQVGAIAARTHDYDPNKWWVSSQGVRTILDEGIAYIYARFLNWKA
>NZ_CP046703|1291643:1327239|1301457_1302651_-|WP_114080554.1|DBSCAN-SWA
MTQQNSRICILGGGFGGLYTALRLSQLPWESTQKPEIVLVDQSDRFLFSPLLYELLTGELQTWEIAPPFEELLQGTGVRFYQGVVSGIDIDQQRVNIHEGPEIPYDRLVLALGGETPLDLVPGAATYGYPFRTISDAYRLEERLRFLEESDADKIRVAIIGAGYSGVELACKLADRLGERGRFRIVEIADQILRTSPEFNREAAKKALEARGVFLDLETKVESIEQNSITLEYKSQLDTIPVDLVIWTVGNRVAPVVKSLPLKQNQRGQISTTSNLQVIDHPEIFALGDLADSHDVEGQQVPATAQAAFQQADYTAWNIWASLTNRPLLPFHYQQLGEMMTLGKNNATLTGLGIKLDGPLASVARRIAYLYRLPTLDHQLKVGFNWLVRPIIETLSK
>NZ_CP046703|1291643:1327239|1315152_1316892_-|WP_114086216.1|DBSCAN-SWA
MSNVQRQATLRPGTAGHQKANTSTFLNPSLASPSIPTLANPIRGFGSQTISKSSTDLQEVQSADEQGVKSEPIKQSPLSHDISRMSLRPQKAFTEGVINRLENAVIQGSGIKNASYGADVVTPSGGQNLPEPVLAKMQTAFNADLSDVKIHTDGQAEKLGSQAFASGNNLHFAQGKYDPESQSGQALIGHELSHVVQQRQGRVNIPKLPGEGNSIVVQDQALEAEADVLGNKAAASPDAITKESIQAKKIDGTVSKAVQQKPIVQNALPVIGAIGAWGASLATESGAAAATIAAATIQAGQAAAQVGGALAPGQSGVQSVQLDNGYMSPVDKQKLQLITQYRLINAYVSHWKRQHPDVPLAPPTQGTAPAPTPAPTPTPAPTPTPAAPAPTASDSPNQSGGTLDLAILEAVKAEVQLQIETLLNTNQKTTDNVEFIWSDSGDHTADTIGTVGAVGFSNIRGTFIKETLQLSSDAAQIPNLDPPSRGQEMDVRQFRGGSMRRGSSMSIGYGDSLSINLTGSGPTINHAGNNGHGEHIYSTDWNWDGNTTQGDFPLYILVDGTPVFNIAKWNGTPDDNSYF
>NZ_CP046703|1291643:1327239|1321759_1323325_-|WP_114086221.1|DBSCAN-SWA
MSESSDELTAFSRRQPLNRRQRPQKVQKVAQKKVKANSQQQAANGREAALARSKNRVAPPPTPSATRRVKSGLVMPTAVKPIPTVKGKIPPFRPGAVMVKTVRMEKPKRGLRSSRKTRLKPMAKTMLYVVRLLIVGVGMGAIVGTVLSVLDPANRISTTSTPQSNSNVARSQPQSTQAPPTASSSLYLSQEIISLKNAVQNLAANYPNLAPGVFLVDLDTGNYVDVNGSTSFPAASTIKVPILLAFFQDVDAGKIRLDEMLTMQQDMVAGGSGDMGSKPAGTKYNALEVVTKMITISDNTATNMLIARLGGMEALNQRFRTWGLTTTTIRNILPDLQGTNTTSPKELSNLMAIVSQGNLVSMPSRDLMLDILRRTQRDTLLPSGLGTGARAFHKTGDIGTMLADTGLIVVPTGKRYIATVMVQRPENDPRAEKLISSISRAAYQEFSQNAVTPNSTTSTIPANGYQPQIGNPALPNSTTGTVPMSGYQPPVISPVPNGMGSTVPANGYQSPVMNPQYYPQR
>NZ_CP046703|1291643:1327239|1326681_1327239_-|WP_114081705.1|transposase|DBSCAN-SWA
MGANLIEQLKQVEDFRTKDGRRHPLWLVLLFVIMGTMNGYVGYRGWGDFVNRHSRVLIKKFGIQKHGVPSYSTIRRVVMGVEFDKLAEKFNDWAKSYVEIEELEWCAMDGKSIKGTVKDYNSSQQNFVSIVSVFACKRGLVVGMKKFENHDKSEIQVVQDLITAMDLQGVVFSFDSLHCQKKLVR
>NZ_CP046703|1291643:1327239|1299378_1300239_-|WP_114080556.1|DBSCAN-SWA
MGSIWEIDFYSRPILDDNQKKIWEVLVCESPLDIGTKPDSLFRYAQYCPSTQVNSGWLRTALQEAINQAGKAPIKIRFFRRQMNNMITKACQDISIPAQPSRRTLVLNQWLEERMKEVYPQEPGYQGGTNPSVRLEKPLPQRLPDALEGQQWVFVTLDAADLAEMPEWEIGFGEAFPLELAKVSPEARIPGILIFSPRALPLAGWMSGLELAFLRFDTSEEPRLLLETGVNESWIVANIKKPQVLAEAKGFEEAKQKANGVHFIGIQSDPKAESFAGFWLLQEVNL
>NZ_CP046703|1291643:1327239|1309461_1309635_-|WP_159402453.1|DBSCAN-SWA
MITERSNHIIPCLKRLRRRSSSLRDAARTLRTGFQSDRLRRAGTPSHNLKLDDETKY
>NZ_CP046703|1291643:1327239|1308477_1309332_-|WP_114086210.1|DBSCAN-SWA
MHTQSKQLNILTPSRELPLYGKRILVTAPRNYAYRLSEQIIKQGGLPVFMPTIETCYLSNYTKLDTALNHIVEFDWIVFTSRNGITAFFHRMNDLNIPVSVVEKCQLCALGKDAESLLSFCGKVDLIPTESSPAGIVAELAKIPQIHNKKVLIPAPEVVGLPEPDVVPNLITDLQQLGIEVTRVPTYITQGLDTSIYSIELNLIHQGMIDVIAFSSTAEVESFLTMVNSQSDYEGCIIACFGPYTTANARKLGVNVSIVSRDYSSFEGFAEAIAEFFTLTSNSH
>NZ_CP046703|1291643:1327239|1317301_1317958_+|WP_114086217.1|DBSCAN-SWA
MTTQTLPPPEVYQGQFGEFTITQSDRTGVIIYRAGLMVAAVSFAIGSALILFNNNPTVVTALTPLYACFSLALGVSLFTIHIYMASLHRMLQIFWAIGSMASVILAISSTEPLALTVYNQPLTLFGVGFIFVALTGIYFKEAFCFNRLETKVLTLIVPLLLLGHLVGILPTQGESVLLGIWATLFLVFALRKTVQAIPADIGDKSVFTYLEEQRLAKI
>NZ_CP046703|1291643:1327239|1320063_1321179_+|WP_114086220.1|DBSCAN-SWA
MVEEGAYWIAWAQISGIGPVLLRRLQQHFGTLATAWNATKVELGEVEGFGFQTLEKVVQQRSRLHPEQLFTKHQQENSHFWTPADADYPRLLLETPSPPPILYYRGEVELQENLGQKPMVGIVGTRQPSEYGIRWTRQISTALAKNGFTVVSGMAEGIDTESHSAAMKAGGRTIAVLGTGVDVIYPHKNRDLYKQILTAGLVVSEYPTKTPPDRTHFPRRNRIIAGLSRAILVMEAPLKSGALITATYANEFGRDVYALPGRVDDHPSQGCLKLLSQGASLIVKELDELLTMLGAIPQIDGVEASTAPEKLMPTLSPELQTVMDAFTSDALPFDFIVQQSGMAAGSVSGALLQLELIGLVSQLPGMRYQKS
>NZ_CP046703|1291643:1327239|1303475_1303877_+|WP_147262440.1|DBSCAN-SWA
MGIKNLASEDQRPPSEGQRPPSEVQCSPSEVQCSPSEVQCSPSEVQCSPSEVQCSPSEGQRPPSEVQCSPSEGQRSPSEGQRPPSEVQCSPSEGQRPPSEAQRSPSEAQILLSRSLIEEKLYVNAALFGTDYI

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_159402613.1|1291643_1292866_-|transposase	ISAzo13 family transposase	NA	NA	NA	NA
WP_114081705.1|1293506_1294064_+|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_159402451.1|1294060_1294597_+|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_114080559.1|1294700_1294895_+	hypothetical protein	NA	NA	NA	NA
WP_114080558.1|1294948_1297588_-	CBS domain-containing protein	M1NSC5	Streptococcus_phage	7.6e-05	26.4
WP_114080557.1|1297792_1299106_-	TldD/PmbA family protein	NA	NA	NA	NA
WP_159402452.1|1299104_1299272_+	hypothetical protein	NA	NA	NA	NA
WP_114080556.1|1299378_1300239_-	Tab2/Atab2 family RNA-binding protein	NA	NA	NA	NA
WP_114080555.1|1300598_1301243_-	HAD family hydrolase	NA	NA	NA	NA
WP_114080554.1|1301457_1302651_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_114080553.1|1302833_1303457_+	radical SAM protein	A0A0K1Y4M0	Klebsiella_phage	1.6e-14	32.1
WP_147262440.1|1303475_1303877_+	hypothetical protein	NA	NA	NA	NA
WP_114080551.1|1303876_1304914_+	iron ABC transporter permease	NA	NA	NA	NA
WP_114080550.1|1305421_1305742_-	multidrug efflux SMR transporter	NA	NA	NA	NA
WP_114081709.1|1306167_1306737_-|transposase	IS630 family transposase	NA	NA	NA	NA
WP_114081708.1|1306727_1307228_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_114086208.1|1307383_1307833_+	Hsp20/alpha crystallin family protein	NA	NA	NA	NA
WP_114086209.1|1308074_1308374_-	2Fe-2S iron-sulfur cluster binding domain-containing protein	A0A222YX16	Synechococcus_phage	7.2e-29	68.1
WP_114086210.1|1308477_1309332_-	uroporphyrinogen-III synthase	NA	NA	NA	NA
WP_159402453.1|1309461_1309635_-	hypothetical protein	NA	NA	NA	NA
WP_114086212.1|1309950_1310661_-	response regulator transcription factor	NA	NA	NA	NA
WP_114086213.1|1311514_1312051_+	DUF1772 domain-containing protein	NA	NA	NA	NA
WP_159402454.1|1312197_1312809_-	HEAT repeat domain-containing protein	NA	NA	NA	NA
WP_114086215.1|1312871_1314851_-	DUF4157 domain-containing protein	NA	NA	NA	NA
WP_114086216.1|1315152_1316892_-	DUF4157 domain-containing protein	NA	NA	NA	NA
WP_114086217.1|1317301_1317958_+	DUF2301 domain-containing membrane protein	NA	NA	NA	NA
WP_114086218.1|1317957_1318647_+	DUF218 domain-containing protein	NA	NA	NA	NA
WP_114086219.1|1318761_1319898_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_114086220.1|1320063_1321179_+	DNA-protecting protein DprA	NA	NA	NA	NA
WP_147262609.1|1321578_1321791_+	hypothetical protein	NA	NA	NA	NA
WP_114086221.1|1321759_1323325_-	serine hydrolase	Q1MVP3	Enterobacteria_phage	1.5e-05	25.6
WP_114086222.1|1323498_1324239_-	RNA methyltransferase	NA	NA	NA	NA
WP_114086223.1|1324412_1325327_+	homoserine kinase	NA	NA	NA	NA
WP_114086224.1|1325370_1325880_+	hypothetical protein	NA	NA	NA	NA
WP_159402451.1|1326148_1326685_-|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_114081705.1|1326681_1327239_-|transposase	ISAs1 family transposase	NA	NA	NA	NA

Sequences of DBSCAN-SWA_4

Nucleotide sequences of DBSCAN-SWA_4

>NZ_CP046703|1893167:1946358|DBSCAN-SWA
GCTACGGTGTACACACAAGTTTGCCCAGAGCGAGTTTCCACCCAAAAAAGGTGGATTCAAATTGCTCAAGACCGCGAACCAAAGTAGTAATACCGGGAGGTTTTTGAGACTTGTAACCAGACCAACCACCAAGCCGAGCAATAATCCAAGTAGCCCAAGGAAGAGAGGAAGGAAGATAGGGATTTTGTTGCAATTGAGTTTTCCCCTCTAAAGTTGGTGAAATGCTAGACAAGCAATGCTGTTGCTCGTGTGAAAAAGCAACAGTAGCAGGTAAATTAGGGTTATCCCGTCCCTGAATCAGTTGTAAAATTCGCACGGCGACTGACAAAGCTAATACAGTCAGTCGTTGAATGGCAGCAATCGATTCTAATTGGGTAGCTTCGAGATTTAAACCAGCAGTTTTGAGGGTGGCAAAAAGTTGTTCAATTCGCCATCGCCAGGTGTACCATCGAATCACCTGTAAAGCTTGTTCTAAACAAACAACTTGGTGGGTGGTGAGCAATCGCCAATGAATCGGTGCTTGACCTGGTGGTGGGTTGACCTCCACGGCTTCCACGGCATAAAGTGTCACACTCGGAGGATAATCTTGTCCATTCAATTTATCTGGACGTTGAATTTTCACCATTGCACGGCGAACAATTAATAATGCCTCTCTTGCGGTTCTACTAGTGCGTGCATCTGCTGGGACATCTACTGTGTAAGTCCCCTCGCTCGGCTGTTGGTTTAAGTATGTATAAAATGATGAGGTCTTTCCCACCAGGCGACGGTCAATGCGCGCTCTGACCAATACATGATTGTCTTGATTTGCGACTGTCACAAATTCCTCATACATATCACTTTCTCGGTCGCCGATATGGGTAATCATTTTGGCTTCACCAACATTGATGCACTGTTGAGTTTCATCAGCTGAACGCAGCCATTTGTATGATTCTTTCTCCTCTATTGGCAATTGGCTATAGTTTCGTTCATGTTTATCTTGATGGTTGATATCTCTAGTCCACAGTTTTACTGTACTTATCCCCAAGGGAAATCCATTTGCTGCATCTAATACTAGTGTGGGATGAATATAAAATCCTATATCCCTATTGTTTCCTACTACACCTAGACCCAAAGCTTCCAACCTGCCTACATGAGACTGCAAGTTAATTTCGCTGGTATCACTGATAGCTAATATATGCTTTCCTTCTACATGAGATACGCAGTGATCTGATAGGCTTCGCACTAATTCCCCTACTGTCACACTCTTATTCTCCAAAAACCGATAGTATCCTATTTGTTCGGCTCTATTTTTACTTATTTGTCGAATGCTGACTGATTGATGTTTTCCCAAAGCTTCGTACAATGCTGCCCCCTTTTTATCAGTCTTGGGTCTCCAAATGCTTTTCCCTCTACTGCTTGCGCGTGTATTCTGATTGGATTTTCCATCGCCTTTTACTCCCCACAACTCCTTCCCTTATTACTTTACTTGGACTTGTGTGTACACCGTAGCTTATTAAGGGGGGAACCAGAAAAACATCTATCAAAGTCCCCCTTTTTAAGGGGGATTTAGGGGGATCAAGATATGTGCAACTTCACATTAAATTGGTATTAGTTCCGTGAATTTTTGAAAAATTGGGATGCTCCCAACGTAATCACTGCTTGCTTATTTCAACAGGATAATTTTTCTAAAGCTCTTGTCAGTAGTGTTTGAGATGTCCTTAACCTGAGTCAGATACCAATGGCAAAACTATAAAGCTATAATGCACTTTTAATCAAATGTTTGCCTGAACTTTAACCGTTTTGATTAATCAACACTCCCAAAACCTCCTCGATACTCAACTGGAAAATGCACCAGGTGAAGGCTATATATTTAGCTGGTTTGATTGGTTTTGTCTTTGGTACCCTCCAGGCTGGCTAATTTTATTTAACCGCCATTGGCAGCACTATCATACCGATATAGACGGTTGGAATTGGCCCGAATATGGATTATTTTTAATTCCTGGCGGATTTTATCTAGCGATGCTGATTCGCTGGTTGCGTCTTGGTTTCCGTTCACCGCGAAAAGAACTTGGTGAATTTGATCCCAAATATCAACAAGCTTTTCGCAAAGAAGTTCTCGGCCCCATCGTCAAATACTATTTTCGGGGAGAATTAAAACAAGTCGAAAACTTGCCGCAAACAGGGCCATTGATTGTGGTAATGAATCACGCAGGGATGAGTTTTCCTTGGGACTTTTTGACTTTGGGTTATTTATTAAGTGAAGCTAGAGGATGGGTGGTACAACCCGTAGCAAGCCCAGCATTATTTGATCATCCTTGGGTTATTTGGTGGCTACCACCTAAATGGTCGCAGGTTTTGGGTGGTGTGCGAGCCGAATTAGATAATTTTGAGGCAGCTATGGCCCAAGATAAAATTATCTTATATGCACCAGAAGGTATCCGTGGCCCTCTGAAAGGTTGGAAAAGACGCTATCAACTAGAAAAATTTGATGTGAGTTTTGTTAAGTTGAGCGATCGCTATCATATTCCCATTCTCCCAGTAGTTTGCATCGGGAGTGAGTTTTTACATCCCTGGGCTGTTAATTTCCAGAAATTGCAACGACTAGTCAAATTACCATTCTTACCTGTATCGCCTTTGATGTTTGCCTTAATTCTGTTTCCTTCAATGGGAATTTGGGCAATGAGGACTCGCTTGCATTACTATATTCAGCCTTTAGAACCAGCAGAATTACACAATTCAAACAAAGGGCGGACAGAAGCTTATCAGCAAGCACAACAATTACGAGAAAAACTGCAATTTAAAATTAATTCAGAGACTATTGATCGAGTAAATATATCTTAAGTAGTGATTAGATGTAGGTTGGGTGGCAATACTTTTCGGTTAAACCCAATAATCTCTCTTTTGGTCTGGGGAAAGGGTAATGGGGAAAGGGAAATTCAAACCCTTTCCCTTTCCCCCTTAACCGAAAAGTATTGGGTTGGGTGGAGGCTTTGCATAACCCAACATTCTGATATATGTTGGGTTGCGCTCCGCTTCACCCAACCTACAATTTTTTTTGCAATATTTTAGCCTTCAGTTATTGAAATGAATTTAATACTATCAATGGATTTAAGTCAATCTTTTAAAAATAATTTACTTAATTATTAAATTGATTTTTCCATAATAAAATTTGTCAGCTTTTGCCCTCTCCGTTCCACCTCTTGCTGTTTCACAACAATAAAATTCTGGCTTTCAAAAAACGGTTTAGCTGTAATACTAGCTTCTGTAAATAACCTTTCAATTCCTAAAGCTTTTGCTTTGGATTCAAGCTGCTCTAAGATTTTTTTCCCAATCCCTTTTCTTTGAAAATCTTTATGACAGTAAAAACGGTCAATATGGCCATTAGCCTCTAATTCCCCAAAACCGATAATTTTACTATTCTCCTCTGCTACATAAGTAAACTTACTTGATAAACCTTTAATCCAAAGGTCGATATCCATATTTGCTGGTGCCCAAGCATCTACTTGTTCTTGTGTGTAATCATGAATATTCACTTCATGAATAGTGTCGTAGAACAACTTCATAATTTCTTCGGTATCAGATATTTGGTATATTCTTAATCTCATTTTTTCAAAAATCAAATATAAGTCCTATAAAAATATTATCAACGCTGGCAAATATTTTGCCCTTAGAGGATGTTTGGAAAGTTGAGCGTTGCTGAATTAAAAGATGATTCTTGTGAAGTGGGCATCCTGCCCGCCCGGAAATACAAGGGACGCTCATGTTGCCCATCCCACAAAATAGTAAAAATTCCTCAGATTAAATCTCGTATAAAAAATTTATAGTACAAATATACTAATTTGCTGCTAAAATGCCTTAAAAGTCAGCTAGCCTTACTTGAGGTAGTATGAAAAAAATCTTAGACACGGACAAAAAACCCATTTTGCTGAAAGTCTCGCTGTTGCAGCCTACACCTGTAACTACTGCAATAGTGCCACTGCAACCCCAACAGGAAAAAATCATCAGTGAACGGGAGCGTTTGATCACACAAGTAGAGCGCATCAATCAGATGGCGGGAGAGTTGGAAGCCGCGATATTGGAGTTGAAAGCGATCGCTAACACACTGAATAGTCAAAAACGTTACCCACTTTTGAAGAAGGAGCTAGGTAAACAAATTTGTCAGTATTTCGCAATTAGTGTCCCTTGGGTGAAACGAAAACCTGACGAATCATTTATTTTGACGACGCGAAAAGTTGATTTATTCCGAGCCGAAAGGGAAGCCGCACTGCTAGCACAGCAACTTCGTCAGCAAACCAAAAAAAGATTAGCATCGCAGCGACACAGAAAAAACAAGAATGGGGCGGAGACTGACACAAGACACTTGTGCAAAAAGGCATTAGTCAACAAATCTTAAAATTATCAACATTCAACGGCAGTTCACGCCTGGGGTTGTAACAGTTATGCTGATTGAAGTGGCAGAAGGAACTTCTTCGTTAAAATTGCTAAATACTACACTGCCATTGCTAATCGCCACCAACTATGGTTGCAATTAGGCAAAACTGCCCTAATATTTGCACTTCCGTAAACCAGAGTGCAACATCAGGGACAATCAATCAGCGCACAGAAGAGGTAAAAAGAAGGTGTTAAAGACACTTTTAGTAATTGCCGTTGGTTTTTTACCGTCCCTGATTTCTCTGTGGGCGATCCGCAAAACCCATGCGCGATCGCGCCTACGGATGAGGCAAGCAGCCATGAATTTTTCAGTAGTGCAGGGACGGCAAAACCTTAGACCGGTTGACAGCGATCGCTATTATTTAGAAGGGGTAGGTTATTTAATTGGCGATATCAGCTGCAAATTTAATGCCCGCTCTGGTTATATGCGTTGTGCTGTCAATCCCGATGGCCCATGTAACGGTTGCCGTCACTACGAACCCAAAGGATTACCTGGTAGCGAAAAAGGGGTTTAAAAGTGCTTACTTAGGATTCAACTAAACTGATGGGGAATGATAAAATCATTACTAATTATAATAATTTGTATTTAGCAGCACTTTGAATATTTGTCTTTGCATGGTGAAATAAGAATGATTTAATAGAATTCGTGCAAAAGTATAAATCTGCGTCATTTTGTTTGTAGATTATGAACATTACTGTGAGCTTTTGCCGAATATCTAATAACTACATGATTATTTAACGATGAACAACGCGATCGCTCAGACAACAGCATTATTATCAACTTGCGCTTTGCTACTAACAGGCTGTGGTGGTGGCGGTGGCTCTGTGACAAATACTCCAAATAGTAATCCAAATAACACTACTAACACTGCCCAGACAACGACTACATCGGGGGCGATTCCTATCGGTATTGCCTTAGCACAAACCAGCAACGTAGCATTACTCGGTCAAGAGGGATTTGTGGGAGCCAGAATTGCCGAGAAGTATTTCAATAGTAAAGGTGGTATTAATGGCACTCCGATTAAATTAATAGCCCAAGATACCAGCGGTGATGAAGCTGGAGCAATTAACGCTTTTCAAACTTTAATTAACAAGGATAAAGTTGTCGGTATCGTTGGCCCTACTTTGTCACAACAAGCTTTTAGTGCTGACCCCATTGCCGAACGTGCGAAAGTTCCAGTTATTGGAGCATCAAATACCGCAAACGGAATTCCCGAAATTGGTGATTATGTAGCTCGTGTATCTGCCCCCGTTTCTATAGTTGCCCCTAATTCCGTGAAAGCTGCACTCAAGCAGAATCCTCAAATTAAAAAAGTGGCAGTTTTTTACGCCCAAAATGACGCATTTAATAAATCAGAAACGGAGATTTTTCAAAAAGCAGTTAAAGAACAAGGACTAGAATTAGTAACAGTTCAAAAGTTTCAAACTACTGATACAGACTTTCAAGCCCAAGCTACCAATGCCATTAACTTAAAACCAGATTTGGTAATTATTTCGGGGCTAGCTGCTGATGGTGGTAACTTAGTGCGGCAACTGCGGGAGTTGGGTTATAAAGGCATAATTATTGGTGGTAATGGTCTAAATACACCCAATGTTTTATCAGTTTGTAAAGCCCTTTGCGATGGTGTGTTGATTGCTCAAGCTTACAGTCCTGAATATCCTGGTGAGATTAATAAGGTATTTCGCCAAGCCTATATTGAGCAATATAAGAAAGAACCAGCCCAATTTACCGGTCAAGCTTTTGCGGCGGTGCAGGTGTATGTTGAAGCTCTTAAGGAGTTGGATAAAAAAACCAAAATCAGCACGTTACCTCTTGATAAACTGCGGACAGAATTGAACAAGCAAATACTAGCTGGAAAGTATAATACACCTTTAGGTGAGATTGCTTTTACACCAGTAGGGGATGTGATTCAAAAAGAATTTTATGTCGCCAAAATTAAGATGGATAAAGATGGGAATACCGGAAAATTTGTATTTATAAAATAGTTGCAACATGGATATCACTCTATTTCTGCAACAATTTTTGAACGGATTATCTATTGGTAGTATCTATGCAATTTTTGCATTGGGATATACCTTAGTTTATTCAATTTTGGGCATCATAAATTTAGCTCATGGCGCGATTTTTACCTTGGGTGCATATTTCACTTATGCCCTCATGGGTGGTAACTTTGGATTTAATGGCTTGCTAGCTAATGCAGCCTTGCCAATAAAATTGCCATTTGCTATAGCCTTAATTTTAGGAAGTACCTTAGCGGGATTGATTGGGGTAGTGATGGAACGGGTTGCTTTTCAACCTTTGCGCCGTCAAGGATCTGATCCCTTATTAACTGTTGTTTCCAGCTTGGGTGTAGCAGTGGTAATTGTGAACTTAATCCAGTATTTGGTAGGTGCAGAAAGTTACACATACCCCGCCGATACTTATGGGAATTTGCCACCTGCGATTAACTTTGGTAGTCCAGATAATCCAATTCCTATTCGCAGCGTTCAGATAATAATTTTTGTTGTATCTGTTGCGATTGTGGCAATTATTACCTACTTTATAAATCGAACTAAGTATGGTAAAGCAATGCAGGCGATCGCAGAAGATCCGACTACAGCTAGTTTGTTAGGCATTAATAGCGATCGCTTTATCATCCTCACATTCTTCATCAGCAGTTTCTTAGCAGGATTAGCAGGAACCTTAGTCGCCTCTAGTGTTAGTATTGCCGGCCCATATTTCGGCATCGCTTTTGGGTTGCGGGGTTTAGCGGTAATTGTCTTAGGTGGTTTAGGTAGTATTCCCGGCGCAGTTTTAGGAGGATTACTCATTGGATTAGTTGAAGCTTTTGTGCCGGCAGAATATTCCGGTTACAAAGAAGCTGTAGCCTACGGAATATTATTTATCATGTTGTTAGTTAGACCCCAAGGCTTGCTAGGTCGTCGGTTTATTCAAAAAGTTTAAAGAGACGTAGCGTGATGAAAACATACACCAAACAAAAATTAACTTTCGATCAATTTTTGGAAGAATGTCCAGAAGAAGGTTTATATGAACTTGTGGATGGGGAAATTGTAGAAGTGCGTGCAACGAGAAATCATGATGATATCGCTGATTTTATATTGTTGAGTTTCAATGATGAAATTAAACATCTAAACCTGAATTACGTAGTAAAAAACACAGCAGTTTTAAAAACCATAACTGCCAATGGAATAGAACAAGGACGCAAGCCTGATGTCAGTGTGATAGATAAAGATGTATGGCGCTCAAATCGTTCTGCTTATTCTGCACTTGAAGAACCCATCCAGCTAGCTATCGAGGTAACATCAACTAATTGGGAAGATGACTACATTGATAAATTAGATGAATATCAACGCATAGGTATTACAGAATATTGGATTGTAGATTATTTGGCAATTGGTTATAGAGAGTATTTGGAAAATCCCAAAGTTCCGACTGTATTTGTTTTTTTATTAGATGCTGAGGGTAAATATCAACGCACAGATTTTAGAGGTTCCGAACGAATTGTGTCACGAACTTTTCCTGAACTGGCGTTAACAGCAGAGCAAATATTAACAGCTTGAAGAAGAATACAGAATACAGAATACAGAATTAATTAGTTAGCTATAAGCGATACCCTGTGACTAGCAAGCTACAGACTCGACATGAATTGTAGATTATAAAATTGAAAATTTAGTGGTGACTGAAACCCTTTTACTCCTGAATTCTGGCTTCTGACTCCTGACTCCTTAATCAAAATATTTTACAATGGCTGAATTTTTCTCTACTTATGAATCACCAATAGTCTACATGGTATTGGAGGCTTTATTAGGATTATCGCTTTATTTACCACTGATGGCTGGACAATTATCTTTGGCTAGTCCTGGATTTTATGCTTTAGGTGGATATATTGCAGCGATTTTATCTACAAAAGTTTTTCCATCTAGTAATAATTTATTTCCCATTCCATTACTTTTATTAGAAATGTTGATTGCTGGTCTAATCTCCGGTATATTAGCTGTAATAGTGGGAATCCCGGCATTAAGGTTACGGGGAATTTATTTAGCGATCGCAACTATTGCTTTTGTAGAAGTTTTACGAGTTGTATCCTTAAATTTAGATATTACAGGCGGCGCTGTAGGAATTTTTGGTATTCCTCAACCATTCCAAAGCCAAATTGAATATTTGTGGATTGCTGTACCATTCTTGTTAGTTAGTATGGTATTATTTTACCGTTTAGAACGTATTCGTACAGGTAGGGCATTCATTGCTATCCGTGAAGATGAATTAGCTGCCAGTGCAATGGGAATTAACCCCACTTATTACAAAGTTTTAGCCTTTACTCTCGGAGCAATTCTTGCCGGAATGGTAGGTGTCATCAGCGCTCATTTTCTCAATACCTGGAATGCTCGACAAGGTACTTTTGATGCTAGTATCACTTATTTGACGATTGTGTTGATTGGTGGCTCTAGAACTTTTTTAGGTTCGGTTGTCGGTGCTATTGTCTTGAAAGTTTTATTAGAAATTGTTTTACGAAGAATCGCCGATATAGCAGGATTACCTAATTGGTTATCCCAGTTTTTAAGAGATGGTAGATTAATTATCTATGGTATATTAATAGTTTTAGGAACTATATTTTTCCCCCAAGGGTTTGTAACTCCAGATATTTTAAAAAAGTGTAAAAACCTATTAATAAAATCAATTTCAAAGACATCCAAGCAGACAAGATAACAAATAACCAATGAAAAATGACAAGTGACAAATGACAAATAACATTGTTTTAGAAGCCAAATCACTAACTCGCCGTTTTGGGGGTTTAGTGGCGGTGAATAATGTATCTTTTACAGTCAATCAACATGAGATTTTTGGATTAATTGGCCCTAACGGCGCTGGGAAAACAACACTGTTTAATTTGATTACAGCTTTTATTCCCCTTTCTAGTGGAGAGTTGCGCTATCAAGGTGCTAATATTTCTCAATTACGTCCCCATCAAATTGCCGGTTTAGGTATTGCTCGGACTTTTCAAAATATTCGCTTATTTGGTGAATTGTCAGCGCTAGAAAATGTAATAATTGCCCGACATTTAGATAATAAAAGCAATCTATTAACAGGAGTTTTGGGATTACCACCAGCGCGTCGGGAAGAGAAAAAAAGCAGGCGAAAAGCTTTACAATTATTAGAAATGGTGGGATTGAGCGATCGCGCTGACGAAAAAGCCAAAAACTTCGCTTATGGGGATCAGCGTCGCTTAGAAATTGCCCGCGCTTTAGCCTTAGAACCGCAAATCTTACTCCTCGACGAACCTGCGGCGGGGATGAATCCCAACGAAAAGCAGCAACTGAGTGAATTTATCCGTAGTCTGCGAGAACAGTTTAATTTGACAATTGTCCTGATTGAACACCATGTACCCTTAGTTATGGGTTTGTGCGATCGCATTGCCGTGTTAGATTTTGGGCAGTTGATTGCCTTGGGTGAACCAGCTGTAGTTAGAAACGATCCGGCTGTAATTGAAGCTTATTTAGGAAATGAATGATAACTAACCAAAGAATTACAGAATCTGTTGCAATTCCTCAATAGTATTTGCAGTGACAATATTCCGTAAAATTGTTTTCAAACGCTCTAAATCCTGAATCTGGTTAATTTCTGGCATCAATTGTAAGCCGCGATCGCTAAATTTCAACTCTAAATTAATTTCAATCGCAGAAAGTATTCCTCGTAGTTCCCCGCTTGCTTTCCCGCGTTCTTCTCCACGCGCTTCCCCGCGTGCTTCCCCTTCGCGTAAAATTTCCTGATACCAAGGTGACTCACGTAATACAGACATATCCCACCTCATGATTTCTTGAACGAGCGTGTTCTCTAAAACAAACGTAGCAAAAAAAGCTAGAACTGTTTCCAGTTGGTTTAGTTGTTCATCAGCACGGAGGATTTGCAATGCTTCTCTAATAATAGATTCATTTTCACCACCTTTGAGAATGGGTACAAATGGTAGTAAGGATGGTAAAGGTTGTTGAAAAGCAATATTGACATCAATTTCCCACAGATTAATTACTCGATAATCTTGTATCGCCCTTAATCCTGCAATATTTGATGTAAAGCTTGTGGGTATTTCGTTGTTACCAGTTTTAAGAATATTGATCAGGACGGGATATGTTGGTAAGTTATATTTTTCTTCTGCAAGTGCAGCATAAGCACGCATCCGACGTGGCATTTGGGATTGATAGCGTAATTGCAATTCGTTGAGAAGCAAAAATTCTCCGTGTTGGGGACTACTAACACGGATTAAAACATCACTTTCCCGGCTAATCCACTGAAATTCACTATTTAGAATTTCCCCAGCAACAATATCAGGAATCTGCGTTACCCATCTTACCCAGTTATTGGGTGCGAGACTGATTAATTTTTTGGTACTGACATCAGCAGGCTTCGTCATTCAGGTATAGATGCACTCAGTAAGTGAGATTTATGGTAACTTGAAATTTAGCATTACACGCAAAAAATGTTTATCAAAGCGCATCAGTGAAATTTAAGCAGACAAAATTTTTATAAAATCTTCTAAAGAATTTACTGCGATCGCGCTATCCATTAAAATTTCTAATTGCTCCACACTTTCACCCTCAAGCCTTGCTTCTACCTCATGAGAAATTTCGCCAAAGCGTTGTTCCAATACTCGGATTAACTGCCGTCGCGCACCCTCTTGAATACCTCTTTGCTCAATCTCGTGATACCAAGGCGATTCTCGCAATACTGCCATATCCCACCTCATGATTTGCTGCACTAAAGGTGTGTCTAAAACAAAGCTAGCAAAAAACGCCAGCAATGATTCTAATTCGTTCAACTGTTTATCTGTTCGTAGCGCCTGTAGTGCGCGTTGCACAACTGATACCTCTCCCCCTCCTCGCAGGATTGGCACAAAGGGTAACAACGATGGTAGTGGTTGCTGAAACACTATTTCGGCATCGATTTCCCACAAATTAATCACGCGATAATCTTGGATGGCACGTAATCCCAAAAATTCCTGTTCGTAACTATTGACAATAGTTAAGGTGGATGGGGGCGGTAAAATGTTGATTAGTACTGGGTAAGTTGGCAATCGGTAGCGTTCTTGTGCTAGAGCAGCATAGGCTCTCATCCTTAGAGGCATCTGTGCTGTATAACGCAGTTGTAGTTCATTTAATACGAGAAAATCTCCGTCAGTGGCACTATATGCCTTCACTAAAACATCTGTCTCCCGGCTAATCCAGTGAAATTCAGAACCGAGAATTTCTTTCGCCACAACTTCAGAACGCTGTGTCACCCACTGTACCCAAGCATCGGGAGCTAAATTAATTAGTCGCTTGCTACCAATATCTGCTGCTTTTGCCACAGGACGCTTAATATATTTATCAGTAATTAATCGTACATTATAAAGATTGCAGTATTCTGGCGTTGGTTTTTAAGTTTAAGCAATGTCTACGATAGGGTACACTGATGCACTCTTTTAAGAAATCTATGATTGATGTATGTTAGGTTTTGAATCAATATTTCTGGATGTAAACCGCCGATGAAAGCCGATAGTAGACCAAACTATACAATTTTAGAAGTTCAAGAGCTTGATGTTAATTATGGCGGTATCCAAGCTCTAAAAAAGATTAATTTAATTATTCAAAAAGGCGAGGTAGTTACTCTAATTGGTGCTAATGGTGCTGGTAAAACTACTACACTCCGCGCCATATCTAAAGTAGTTAATTCTAAGAGTGGCGTAATTTTATATAATGGACATAATATTACCCGCCGCCAAACTCACGAGGTTGTACAACTTGGTATTGCCCATTGTCCTGAAGGACGTAGAGTATTAGCGCGGCAAACAGTATTTGACAATTTACTTTTGGGTGCTTATATTCGCTCCAACCAAGCTGAGATAAAAGCAGATATTCAGCGCCAATTTGAGCTATTTCCCCGCTTGTCACAAAGACGCAATCAACTAGCAGGAACCCTCAGTGGTGGCGAACAACAAATGTTAGCGATCGCACGCGCTGTCATGAGTAAACCACAACTTTTACTGTTAGACGAGCCTAGCTTAGGTTTAGCACCTGCGATCGTCCGGGAAATCTTCTCGATTATTGAAAATCTCCGTGCTACAGGCGTGACTATTTTGTTAGTTGAACAAAACGCTAATCTGGCGCTGCAAATTGCCGATCGCGGTTATGTTTTAGAAGCTGGTTCTATTACTTTAACAGGCGCAGCATCAGAATTAATTAGTGATGAGCGAGTTAAAAAAGCTTATTTAGGGTAATTAATTAAATGAAACTTTTGGAGATACAAAAAGATGATAAAATCACTAACTAAAACCTTTACTTTAGAAGAATTTTTAAAGCTTCCAGAAACAAAGCCTAGCTCAGAATACATCAACGGTCAAATTATTCAAAAGCCAATGCCTCAAGGAAAACATAGTATTCTTCAGGGTGAACTAGTCAGTAATATCAATTCTGTAACCAAACCTCAAAAAATTGCCCTTGCATTTCCAGAATTGCGATGTACTTTTGGCGGACGTTCAATTGTCCCTGATATAGCTGTGTTTGCTTGGGAACGGATTTTATTAGACGAGCGTGGAGAAGTGGTAAATGTCTTTAAGACATCTCCAGACTGGACGATTGAGATTCTTTCACCCGATCAAAGCCAGACTAAAGTAACTGGAAATATTCTACATTGTTTAAAACATGGTAGTCGCTTCGGTTGGCTAATTGATCCAGATGAGCATTCTGTTTTAGTTTATCCACCAAAGCAGCAACCAGAACTTTTACAAGAAGAACAAGAAATATTACCAGTTCCAGATTTAGTGAACGGCTTTCAATTAACTGTAGGGCAATTATTTGGATGGTTAAAGTTATAAGCAATTGTAGAAATTCATATTTATCTTAATCTTATTGGATTTGTGAGAATTGCAACCCAGAGATCCCCGACTTCTTTAAGAAGTCGGGGATTTTGTTTCTGCGCGTTTGATTCAGGATTGCTATACCAATTGTGATGAATAAAACTACACTAACGCCGCTTATAACTTTTCCAAATAATTTATATTATTAATAATTATTACGATTTTTGTCTTATATTAATATTTGCAGCCCTCCTTGCAGATATCTATATATTTGTTTAGCGGCGAATTCTATTCACCGGAATCATTAAACCCATGAGTCAAATAGTCTGGATAGCAAGACACGCTAACCGCCTCGATTTCGTAAACCCCGATTGGTTTCTCACCGCCGAACGACGCTACGATCCACCTTTGTCTGATGATGGTATGGTACAGGCACAGCAGTTAGCTAGACGATTGAAAAAAGAAAATATTGGTCATATTTTTGCTTCCCCTTTCCTGCGAACCGTACAAACGGCAAACGCAGTTGCAGAATTGCTCAACTTGCCGATTAAATTGGAAACAGGTTTGAGTGAATGGCTAAATCCAGCTTGGATGACAGAAGAACCCGAAAGACTTTCAGCTCCAGCATTAGCAAAATTATTCCCCAGAATTGACACCAGCTATACCTCGCGCATCGCCGCCAAATATCCTGAAACTCACGAAAAAGTACGAGAACGTTCTGGGCAAACTGCCAGATGTTTAGCTACTGAGTTCTTCCCAGAGGATATCCTGCTAGTGGCACACGGTGCATCTGTGTTGGGGGGAGCAATGGGGCTGGTGGGGGAAATTGCCAAAACAGAAGTCAAGGCTTCTTTATGTTCATTGGTAAAAGTAGTACGCGAAGATCCAGAATGGTTATTAGAACTAACGGGAGATACTTCCCATTTAACCCACATAGAAGAAGTTATTCGATTTGCTTAAACCTCTGATAGAGATTTGTGTTCATAGGTTCTGCTAGGTTGGGTATATCCTACAAATAAAGTCATTAATCCGCAAATAAGTTCTATGACATTGTTACTAGCAGGAGACATCGGCGGTACGAAAACTATTCTGCGATTGGTTGAAACATCAGATTCACCAGCTTTACATACTATTTATCAGGAAAGTTATCACAGTGCTGATTTTCCCGATTTAGTACCCATAGTGCAGCAGTTTTTAATCAAAGCTAATACACCAATACCAGAAAAGGCTTGTTTTGCGATCGCAGGGCCTATTGTCAAAAATACTGCCAAACTTACCAATTTAGCCTGGTACCTAGATACCGAACGTTTAGAAGAAGAATTGGGTATCCCACATATTTCTTTAATTAACGACTTCGCCGCCGTTGGCTATGGCATTTCAGGTTTACAAAAACAAGACTTGCACCCGTTGCAAGTTGGGAAACCTCAACCCGAAACCCCGATTGGAATTATTGGTGCTGGTACTGGTTTAGGGCAAGGATTTTTAATTAAGCAGGGAAACAACTATCAAGTTTTTCCTTCAGAAGGTGGACACGCTGACTTCGCGCCTCGGAACGAAATCGAGTTTCAACTGTTGAGATACCTGTTGGGTAAACATGATATCCAGCGCGTTTCTGTGGAACGGGTGGTTTCTGGAATGGGAATTGTGGCGATTTATCAATTTTTGCGCGATCGCAAATTTGCCACCGAATCACCAGATATCGCCCAAATCGTTAGAACTTGGGAACAAGAAGCCGGACAAGAAGAGAAAAGTGTCGATCCCGGTGCTGCTATTGGTGCAGCTGCACTAGAAAAACGCGATCGCCTTTCCGAACAAACCTTGCAATTATTTATAGAAGCTTATGGTGCAGAAGCCGGCAATCTCGCCCTTAAACTCCTACCTTATGGTGGCTTATACATTGCTGGTGGGATTGCTCCCAAAATTCTCCCCTTAATTCAAAATAGCGGTTTCTTGTTAAACTTCACCCAAAAAGGCAGAATGCGCCCCCTCCTCGAAGAAATACCTGTGTATATTATCCTCAACCCGCAAGTGGGGCTAATAGGTGCTGCTTTATGTGCTGCTAGGTTATAACAGCTAGCATCATCAGTGAGATTAGCATCTCAAAAGGTAAAACTTATGACAGTTAAAAGTCTGTTGCCATTAATCGCCGCCACCTTTATCTGTGGTGGTTCTATTCTCGTGGAAGCGCGTCAACCTAAACCTCCGGTGGTTGTTGTCAAACCAGCCGTCCCTAAAATCGTGCAGCCACAATGGAAGGTATACACCGCTCCAGATGGTCGCTTTACTATTTTGATGCCGGGAAGACCCAACAGAAATACCGAATTCCAAAAAACTTATATGGGGGAAATTGCCTTAGAAATATTTGCCGCACAACCGCCAAAACAGGAAGTAGCATACATAGTTGTTTACAACGATTTTCCTTATAGTTATGGTAAAATAACTGACCCACAAGCTGTACTGAATAATGCACGAGATATGGCTTTAAAGACTACGAAAAGCAATTTAATTAGTCAAAGAAATATTCGTAGTTATAATAATCATCCTGGCAAAGAAATTGAGTACATCAATTCTGGAGGAAAAATCACTAAAAGTAGAATGTATGTTGCCGAAGGAAGGTTATATCAAGTAATGGCAATAACTACAAAAAAACAGCAGAAGACATTAGCTAAAACTATTACTGGGTATTTAAATTCCTTCAATTTAGTTTTGAAAAAGTGACTTGAAGAAGAATTCAGAAGCCAGAATTCCGAAGTCAGAATCAAGACGCGACGCTCGTTCCTCTCTACGAGACGCTGTGCGAACGCTAACGGTGCGCTATCAGTCGTGGGTCTGAATCCCCGACTGATTGAAGACTACGAGGTCTTAAACCCCTAGATTCAGACGCTCCAGGATGAGCTAACGCTGCGCTATCCACCAGCGATGCACTGAGTTTCGGCTACGCTCAACTACCGCCGGTCGTTGTGTCGCACAAAATACCCAACTGAATTCTGACTCCTGACTCCTGAATTCTGTTTCGATAAAAAATCTTGGATTTTCGCTAATAAAATTTTTCCATTGACTCCTAAATTCTGCTCTATTTTAATTATTTAATTTTTTAGCTCATTTTATACAATTTATACGCTACTCAACCGCTTACTCAAACATGATTTCTAACGCTAGGATGTCATGATAAAAATTGTTAGCAAAATTACACGCAACCAAGTGAAATAAATGGCTGATATTATTGATCGTGCCGTTAACGCTGGTTCTTTTAGCACCCTAGTTGATGCAATCAAGGCTGCCAATCTCATAGATACTCTCAAAGGGGTTGACTCGTTTATCGCCTCTGCATCTACAGATCAAGCATTCGCAAAGCTTCCAGCCGGTACTGTAGAGACATTGCTTGAAAATATTAATAAGATCCAGGAACTCCTGACGTATCACGTCGTTTCCGGTAAGGTGATGCCCATAAAGCCGATTGAAGGTTCAAGTTTTAAAATTGACCCTTTCAATAGTTTCAATGCAGATTATAATTCACAGTTTCAAAATCCGATGCTGCTGATGATAACTGTGTCATCCACATCATTGTTGATTCCTCGATAAATATATAGATAGATAGCGAATCAATACGGTTCAGTTAAGAGAAGAGACGCGATAAATCGCTGTCTCTACAAAGGAATGCCATTTATCGTGTCTTTGTGATCTATAACTTTCATCAAAAAACTTTATCCGAACCGTATTGGATGGCGAATAACATCTGTGAGGTAGAAACTATTTATAGTCATTACCTCATTACTATCTATATATATTTTAAGTAGCTCAAATTTTCTTAGATAATTAGACCTCTATCCTAAGCTCGACTTTATCCAAAATTAAGAGGTTGTTTGAAAAGTGGTTGACTGTGATTTTAGGCACTAACTGATCCCCCCTAGCCTCCCTTAAAAAGGGGGAAACCGGAATCAAAGTCCCCCTTTTTAAGGGGGATTTAGGGGGATCTATAATGTTTTGTTACCGAGAAGAAAACTTTTCAAACATCCTCTAAGAACTTGGCTTTCTTTATTCGGCAAAAACCCTGGCTTTTTGGCAAATACTTTTTCTATATCACTGATTATCGATCAAGTCCAAAAACTAAAACTAGCTTCCTACAAAGGTTTAATGGTCAGGTTTTGGGTTTCGTAAAAATGGATAAAGTCGAGCTAAGAGGATGTTTGAAAAGTCTTCTTGTCAGCATCAAATAGTTTTAGATCCCCCTAAATCCCCCTTGTAAAGGGGGACTTTGATTCCGATCCCCTCTTTTTTAAGGGGGGTTAGGGGGATCAATAAGCACCTAAAATCGCAGCCAACCACTTTTCAAACAACCTCTAAAAAGAGAGAGGCTTTGAATTACCTGTAAGGAAACATGGAGAGCTATATTTCACTCTTTTAAAGTTGTTTCACTTAGGCAATACCACTTGGTTAAGAATATTAGTAGGTTGGTTTTTGTTCCTAAACTCAACCTAAATATTTTACTTTCTAGGTTTAACCAAGAAGTATTACAGTATTATTTATCTTCAAATTTGCCTGATAAATAAAAACAATATCAGCTAAATAAATCCAAAAATCAAGTGTTTGCAAATGAATCATTTATTAACGAGACAAAATAATTTTATTACTGGCTCTAGCCAGAATAATATATCTACAGAAATAAGTCAATCTATGAAGGAAAAGTATACTTGTCTTTGCTGTTCAAATGCTTTACTACGTCACGTTAATTCAGGGGGAGCTTACTGGCGTTGTAGCTCCTGCTATCAAGCAATGCCAGTGTAGAAAACAGAATCAATAATGTCCTTAATCAAGTTAAATCAATCATTGGTATCTCTCATGAATTTATTTCAATCTAATCAATCAGAGTTTGCCTGGTGGGTAGAAATTAATACTGCTGTTCCACGCTGTACTTATTACTTTGGCCCTTTTGATAGTGAAAAAGAGGCACAACTTTATAGAAGCGGCTATGTTGAAGACTTATATCAGGAAGAAGCCAGAGACATCATTGCGCTAGTCAAGCAATGTCAGCCTGATGATTTGACGATTTTTCATGAGAAAGCAGAAGTCCAAATATCTAGTTTTTGAAGCCCATCTCGCAGATATTTTGCTAAAAGGGGTTTTTCAATAATATAACTGGTTGCATAATTTTGAGGTATAAGCTCTACTACTTGCTTAAGCAAGTTTAGGAAGTCTTCTGCTTGTTCACTTAATGCAGTTCTACCAAGCCACATCAAAGCTATTACCTCTACTTTTTCTTCTTCGGAGAATTCATGAATATATTTTTGCAGGATATTTATTGAACATCTCCCTGTAATATTTAAATCCTCTAAATAATAAGACAATTTATCTATAAATGTTTCTGGTTGGTTTGTTCTCCCATAACCCATTGTTCCATAGATTAATTCAGCCATCTCAATAATTTTATATATTTTGTTAATTGACAATAAACTCATATTTTTTATTAGAATTGGAGTCAATAAGAAAAAATGTAACAATAGAAAAAAATTAGCAATTTATGTTGCCAAAACCTTATGGATACATAGAGAGATTGAGATGATATCTATATAGTGCAACTATGAACCATAATCAAGTAAGTAATTGCTAAATAACTCTTCAACTTCTACTTAAGCATTACAGATAAGTATTTGAATTCAGGTATTACCGAAAGCTTGAAATGTATAAGATAAGTGTATAACGTTTGATTTCGACGCAAAACTTTAAAAAGCTGAGAGTATCTCTGGGGTTTTGTATAACTTTAAACGAATAGAATGGTAGTATCACACAAAATCTATATAATTGCAGATATTAATAAAAGTTAAAGTCAATGATTTGAACATCAGAGTTTTTGTCTATGGTCAAGCGATCGCTCCAAGCATCACTCATCGGTATTGAACAGGCTAAAAGAGCATTTGCTCTCAAGGGGTGGACTCAAGACAATTTGTCAGCCGAAGTTAACCTCAAGACTAGACAACCGATTTGGCGATTTTTTAGTGGTCGTCCAGTTGAGCGTCATACTTTTATTGAAATTTGTTCTGTATTAGAACTGAATTGGCGGGAGATTGCTAGCAATCCACCGGCAGAATTCATGGAACTAGAAGAATACGGCCGGCCCCCCGTGCTGGATATTGATGGCTTGGTGGAAAAAGTGCGATCGCAACGCTTCGACAAAATTCAAGACCAGTGTGGGATTTTGCAGTTATTGGATATCAGCCGTCCCGTTGCGATCGATGACATATATATAGACGTGAATATTTTGGAGGAGATTGCCAGTCAACAGTGGTTAGAAATCACTGCGCTGCAAAACCTAGATCCCAAACAATTTGACCGTTTTGGCTTAGGTGAGGCCGATCAAAACCAGATACCTGGTACACAGGCAGTTGAAACATACTCTAAGCTCAGGGTACTAGGCAAACCTGGGGTAGGTAAAACCACCTTTTTACAATATCTCGCCATTCAATGTAACCAAGGCACATTTGCAGGGAACTTAGTTCCGATCTTCATTACCCTGAGAAATTTTGCTGAAGAATCTAAAGTCACCAACGAGTTCAGCCTATTAAAATACATCCGCCAGGAGTTCCTCACATCTGGAGTTTCCGATTCCTCTGCTATAGAAACTTTACTTAGTGCAGGCAGAGTCTTAATTTTGCTTGACGGTATGGATGAAATTCTTAACCAACAAAGCAATACTGTCTTAAGCGAAATTCGCAGGTTTTCAGAAAAATATCACAAAAATCAGTTTGTGGCAGCCTGTCGAACAGCATCTCAAAAACTCAGACTCCGAGGCTTTACCGATGTTGAGATTGCACCGTTTACCTCAGAACAAATCATCGCCTTTGCTCAAAAATGGTTTGTGGCCTTTACCAAAACCAACATTCAAGACGGTCAAGCGCTGTCCGTTCAGTTTGTTGAGAAGTTGGACTTAGATGAAAACTGGCAATTTCGCCAACTCGTAGTTACACCCCTATTTCTGCATCTTGCTTGCTGGGTGTTTCACGGTCAAGAAAAATTTCCGACTAAGCGGACTGACTTTTATAAGCAAGGTTTAGACCTTCTATTGGGCAAATGGGATGAAGCCAGAGGTATTGAACGTGATGAAGTTTACCGAGGGTTTTTATTACCACAAAAGCTCAAGTTATTGAGTCAGATTGCAGCAGCGACATTTGAGCAAGGTCAGTACTTTTTTGAGCAACGCATCGTTGAGCAATACATTGGTGACTATATTCAGAATCTGACCAAAGCGCCAATGGATGCCGAAGAACTGCAAATAGAAAGCGAAGCAGCACTGAAAGCAATCGAGGCTCAACATGGGCTACTAGCAGAACGGGCGCGGGGAATTTTTTCCTTCTCCTATCTGGCGTTTCAAGAATACTTTACAGCAAGAAAAATCGTTGCCAGCCATAATCTAGAGGCATTTGGGGAAGCTTTAGAAGGATTAGTTAGTCACATTACAGACCCGCACTGGCACGAAATTTTCTTGTTAACAGCTACCATGCTCCGAAGTGCAGACTCTTTAGTACAGTTGATGAAGCAACAGATTGATGCACTGGTTGGCCAAGACCCTTATTTACAAGAATTTTTGACCTGGGCGAGCCAAAAATCTCGTACTATTCCCAGCCAAGCAAAAGAGGCAACAACTCGAGCCTTTTACCTTGCCTTAAGTCGGACTCCTCACATAGCTTCTCACTTTGCCCTAGCCAGCAGCCTCGACCAGGGAATGTTTCTGGATACGGCTTTAGATGACCTACTGCTCGAATGTGCAATTGATGGGAGCCAGGACTTTGCCCACATCCACGCCTGTGGAGATGCTCTCTCAAACATTTTGGGTATAGTTCTGGATGTTGGACTTCATAAATCCCTACAACAACTCTCTGACCAATTGCCAAGTTCTCGTCAAAATCAAGAACGGCTTAGGCTATGGGGGCAGACAAACTATGCAGCCTGGGCTGAACAGTTAAAGATGAAGGTCATTAATTATCGCAACATTAACCACCAGTGGCAGTTTAGCACCGAACAACAACAAGTTTTGCAACGATACTACGATGCCAATAAGTTACTACTCGATTGTCTGCATAGCAATTGTGAAGTGACGGCTGCTATCAGGCGAGAAATTGAAGCCACCTTATTGTTACCTCAAAAGGAACTTGAGGACAGGGAATGGCAATAATCCTTTTGGTTAATTACGCAAATAGGTAGTTGCCAAATTAGTTTTCATTACGTTTTGTGTCATAGTCAATCAACTAATTTAGTAAATCAAACAACACTTTGCCATATTACAGAAAGTTTTTCATTTAATTTCTAGCAAAAATCCTTCTTTCGGTACTTTTCTTTGTAACCACTCTTCTCCTGAAACAGAAGCTGCGCGTAGCTTACTTAGATTGGTACGGAAACGTTTCCAATGAATGCGCCTTTTGACCAAATCAACTTGAGACACGATAGGGTCTCTAAGAGTTGCCCAGTAGAATTTCGCATCTCTACTTACTCATTTTCAACCCACTTTGCACTTAGAGCTTTAATGGCAGGTCTTGTTATGAATTTAATCAATGGCTTTTGCTTGACAGATGGGATACTCAAAGGTGTAGAAGTACTCGTTGTAGACAACGATCGCGATAGTAGAGATTTGTACGCATTTTTACTCAAAGACCAGAGTGCAAATGTGATTACTGCTGGTTCAGTAAAAGAAGCTTTAGAAATCCTGAGTTGGTTCACGCCCAACATCCTTGTCTGTGAAATTAGGTTTTTGGGTGAAAGTATTTATACATTGCTAAATACATTGAGTGCTATGGAAGCAGACAATGGAAAGCATATCCCAATTATTGTGACTTCAACATCTACCACAGGTACTCATGACCTAATTCCAAATGTGGAGTTTGAAAAATATTTACTTAAACCATTCGACCTTGACAAATTTGTTTCTATGATTAGAAATCAAGTACAGGAAGATGTGTCACAAAACTTTTGCCCCGATGTATTAGTTTTACACTAGTAGTTCGCCAAGTGAACTTGGCGGGGTAAAGGGTAAAGGGGAAGGGGGAAAGGTTTCAAATCCCTTACCCCTTACCCCTTCCCCTTTACCCAGCCATCACGCAGCATTTTTGGGTTGGCAGACTACTAGTACACTGTAGCGGAAGCGTATTGCCCGATTACTAAGCACTTCTCAAAGCCACAATTGGGTCGAGTTTAGCAGCGCGACGTGCAGGAACAACACCAAAGAATAAACCAATACCACCAGAGACACCAACTGCCATAGTAATTGCTACAGGAGAAAGACTTGCTTCTAAGGGAGTTAAGGCTCCCACTAATAGAATGCCACTGATACCAACCGCAGTCCCAACTAAACCACCAGCTGCGGAAACTATTACTGCTTCAATAATGAACTGTAGCAAAATATCTTGCTCAGTTGCCCCGATCGCTTTTCTCAATCCGATTTCTTGGGTGCGTTCGGTGACGGAAACTAGCATTATATTCATAATGCCAATGCCGCCGACAAACAAAGATATCCCTGCGATCGCTGCTAGCATAATTGTCAATGCACCTGTGATTTGACCAACAGTTTGCAAAGCATCCTTTTGAGAGCGGATAGTAAAGTCATCTTCACCATTAATTTTGTGCCGTAGACGCAGCAAATTAGCAATTTGAAATTCTGCTGCATCCACGCTCTCTGAATCACGAGCGGCAGCAACGAGATAATCTAAAGCAATGCCATAAGGAGAATTCTTTCCCACAAGTCGGTTGGCTGAGGTTGTGATTGGTATGAGCGCTGCATCATCATAATCTGCTCCCACGCTGGAACCTTTGGCTATTAATATCCCAATCACTTGAAAGCTAGTATTTCCAATTCGCAATTGCTGACCGATAGCATTACTATTACCGAATAGTTTTTCTGCCAAGTCTCCACCTAAGACAACGACTTGGTTACTTCGCTTCATGTCTACCTCGCTAAAAAATCTGCCTTTAGCAGTTTCAAAATCCCGCACTGATAAGAAGCTGGGAGTTGTACCAATGATGTTGACATCAGTGTTTCGGTTGCTATATGTAACTACCTGTCTCCTGTTTAACTCTGGCGCAACTCCTACTACTGTTGGTACTTGAGAAGCGATCGCATCGGCATCTTGTAACACCAGAGTTTTTGGCACTTCAAAGGAGATACGCTGAGTTTCTCGATTACCTGGCAGTATAAACAGCACATTTGGCCCTAATGACTCTAGCTGTTTATTCACATATTTTTGCCCACCTTCGCCAATGCCAATCATGGCAATTACTGAGGCATTACCAATAACGATACCCAACATCGTCAGGGCACTACGCAGCTTATTTGACAGCAGGGTTTTACCCGCCATTTGGACACTTTCTAAAAAATTCATGTCTTAATAATTACGAATTACTCTTTTCTTTCGCCTTCTCGATTTTGTAGTCTTTGGGTGGATTAACAAAAACGCGATCGCCTTCTTTAACTCCCCCTAATATCTGAGTTTGGTCTTGAATCTGTGCCCCAACTGTAATTTCGCGGAACTGGGGTTTATTCTTTGCATCTGGTACAAGTACGCCAGTTTGACCCTTTTCAGTGACAATTGACACCGTTGGTAGCACCAAAGCATTATTGACGCGATCGCCTAAAAAAGTCAGATCCACATTTAAGCCAGAACGCAGTTTATCTGTACCAGTATCAAGAGCAACCCGCACCTGGAAGGATGTCACCCCTTGTTCCACCACTGCTTCGGGGGCAATTAAGCGCACATGACCTTTAAAAACTTGATCAGGATAAGCATCAGCGACAATTTCCACCTGCTGTCCCGGTTTAATTCTGCCAATATCGGCTTCAGGAACTTGAGCTAATATTTCTAACCCACGTGCTACGGCAACAATTGAACTAGAAGTTGCCGATGCGCTAGTAGAAGCAGAAGTGGTGGGTGTCACAAAAGCACCAGGTTCGGCATACTTTTGGGTAACAATTCCCGAAAGCGGAGCGCGAATAATTGTATCTTCCAACTGCACTTGCACACCTTTCAATTGAGCTTCAGCACTGGCTACAGCCGCTTGGCGCTGGACAATTTCCTCAGAACGAGTACCATCTTCTAACAGTACCAATGCTGCCCGTGCTTCATTAACAGCTGCTTGACGTTGGTCGATTTCCTCAGTCCGAGTCCCACTTTGGACTAACGACAATCGTTTTTTAGCTTCTTCTAAACTGGCTCTAGCACTCTTGTCTTCGCTGATGGCTTGATCGAGTAATTGTTTTTTCTCTGCTCCCTCTTTATATAGGTATTGGTAGCGCTTTACCTGTTCGCTGGTGTAATTCACCTTTGCTTGAGCCGCATCCACTTGGGATTGAGATTGAGCAATCTCTTGGGGACGATTACCAGCCCTAGCTTGGGCTAACTGGGCTTGAGCTTGTGCTAACCGCGCTTTTGCTTGAGCGATTTCTTGAGGACGACTACCAGCAAGGGCTTCGGCTAATTGTGCTTGACTTTGGGCTAAGTTAGCACGATACTGACTCCTTTGAGCCTCAATACCTGCGCTATCCATGCGGGCGAGAATTTGCCCTTGTTGAATGCGATCGCCTTGTTGTACATATAATTGCGATAGCACACCGGGGTTCTTCGGACTAATATTTACGCTCTGAATCGGTACGACTTTACCGCTAGCTGTAATTCTCAATGTGACGTTTTTCGCCGCCACTGGCACAGTTAATTGAGCAATATCTTCTTTTTTCCCTTGATTCATCAGGGTGTAGGTTGTGATAGTACCAACAACCAAAACACCCCCTGTTATCAGCCCCATCAACCAGCGAAATGGATACTTAACTTTGCCAATAACAGGAATTTCTATGTGCGTAGCCATATCTAAAAGCCTAATTAATCTTGCTTTATGGGAGTAGCCTGTAGTTAAAGGGCGAGTACAGGAATGGGGAATTGTTAAAATTTTTCGATTAAATCTTTATTAATAAGCTAACAACTAGACGCATAATTAGCTTTATAGTTGCTTAATATTACTTCATGATAGGTGTTACATGTCTGTATGCCTTCACCTGAATGGGTGACTTTATACCATTTCTGTTTAAAATAGGTTGAGTGGAGTGGAGCGTAACCCAACATATATCAGAAGAGCGATCGCAACCAACTGCTACTAGAAACGGAAATGAGTTGAGCGAACAACACCCTGATGTCAAACAATTATGAGAAATAAACGCAGTTAATGCCAAGTTATAGGACGTTTGCCTTTGCTACGCTTACCTTTTATCAAGTTAAAGTGGCATCAGGTGTGTTGGAGATAAATATTCCTAAATGCATGTTACAACTTCTTACTTTTTGGTGGTAAAAAGCTAAAAAAATCTAATTATTATACTCATGTGAGCATTATTTTAATGCTTGTTAGGAGTATGAGTATGATTGCTAGTACCCTGCTGGAAGAAATAGAAAAGTATATCCCTATTGTGGGAGATATAAATATTAAGAGTCCATTTGCATACCAAGTAACTCGTGGGGCGGTTGAGGTAGTTAACACAGTCCAGATGGCAGTAGCAGAAGCTTATATCAACGGATTAGAAGTTCCTGATCCCGTTCTAGAATCGCTTTTTGATACCTGTATGCCAATTTTCTTTCAGTATTTCCCATCCCTACTAGCACCGTATGAATGGGTAGGGAAGGGGGTTAGGGGGTTAGGTTTTTAGTGGACTTTTCCACATAACGTGAAAAGTCAGGGCAAGGAACAGACTTTTTTTCTGAGCCATCTGTCAATCAAAATATCAGACGGATGTCTTTGCTTTTGCCTTGAACACTGGGTTTTGAAAGTTGCGGTTTCTGGCGCGAGCAATAAGTTCTGGTTCAGAAGGCACTCTAACCTTTGACGCTAGCTTCAAGAACTCAAGGATTTTAATGAACCAAAATGTTGGGTCTGGAAGATAGGCAACCCGGCCTTCTCGCACAGTTATGCCATGCCGAGCTGACCCCTGGAATGCATGATGAAGATTATGCCAGCCTTCACCCAAGGTTAGAAATGCTACGAGCCAATGGTTCCGACTGTAATCATTAGTTTTGAACGGTTGCTCGCCCAGTATGTGGCTGAGTGAATTGACGGTGGCGACACAGTGGAAGAGGACAGTCGTGCTGAGGAAAAAAGCGCCGAGATATTCAACTCCACCAATGTAGTATGAGAACGCACCAAGAGCAAAGGTGGGAATGAAGTGCAAACGATCAACAATCTTCAAAACCACATTACTCTCAACATCAGTGGGAAGTTTCGAGGGAAAAAACTGTGGGGAGAATAGCCATCCAGCTTGAGACCACCAGAATCCTTTGATCCCCTTGAAAGGCATATAGGGAGAATGAGGATCTTTTTCATGATCTGAGCTTTGATGATGCTCCATGTGGTGAGCTTTCCACCAACTTGGCCCCATCTGTCCGGCTGAAGCAGCCACGATGCTTCCAACGCATAGAACTGAGCTTGGAGCCTGGTAGCTATTGTGGGTGAGTAGCCTATGATAGATGCCAGTAGTTGCAAGCATTCGTATTACATATAACAACACGGCCCACAAAACAGCACCCCACGATAAGCCAGTAACAATAATCAGTAATGATCCTAAATGACTCACCACGATCAAAGTAGGGCCTAGTATGTAAGAAATAATCGTGAGATGAGAGTACTGCTTCATTAATCTTCTAATGTCCTTAAGCTTCAAAATAAAAATGCACCACATTTTCGCCGCAGTCAAGCTTGCGGACAGCAGAACGCCCACCCTTGTCAGCGTTAGTACCTACACGCATATCTTGGCACAATTCGCTTGGAATATGAAAAGCAGTTTCAAACACAAGCAGTGGCAAAAAACCAGTGAAGAGTTTCTATAGCACAATCGGATTTGAGTTAAAATCTCTAATCCCGTAACAGCGAGTTGACCTGGAAAATGTCAAAATTAAATGAGTTTTGCGTAGGCGCATTCGCGCAGCGTCTCGTAGAGAAGCGACTTTATTAGCGCAGATTTGAGATAACTTAGTTGAAATTTATGGGCAAGCAACGTGTTCTTTCTGGAGTTCAACCAACGGGCAATTACCATCTAGGTAACTACTTAGGAGCCATTCGCAACTGGGTAGAAGGTCAGAGTGAATACGAAAATTACCTCTTTGTGGCTGATTTGCACGCGATTACAGTACCACACGACCCGAAACAGTTGGCAGCTGATACCTACACTCTTGCTGCTCTCTATCTAGCTTGTGGTCTTGATTTAAATCACTCCACTATCTTTGTACAATCTCACGTTTCAGCCCACAGTGAACTCACCTGGTTGCTCAACTGCATTACACCTCTAAACTGGCTGCAAGACATGATCCAGTTTAAGGAAAAAGCTGTTAAACAGGGAGAAAATGTGAGTGCAGGTTTGTTGGATTACCCAGTCTTGATGGCGGCTGATATTTTGCTTTACCAAGCGGATAAAGTACCAGTGGGTGAAGACCAAAAGCAACACTTGGAATTGACAAGGGATATTGCAGCTCGGTTAAATCACCAATTTGGTAAACCAGATCAGCCAGTTCTAAAGTTACCAGACCCTTTGATTCGTAAGGAAGGGGCAAGGGTGATGAGTTTAGCGGATGGTACACGCAAAATGTCGAAGTCCGATCCTTCGGAGTTAAGCCGAATCAGTTTGCTCGATTCACCCGAACAGATTCAATACAAGATTAAGCGTTGTAAAACCGATCCGATTCGTGGGCTGACTTTCGACGATCCAGCACGTCCAGAGTGTAATAATTTGTTGACGCTGTACACATTGCTTTCTGGGAAGAGAAAGGAAGATGTAGCAGTTGAGTGCCAGGATATGGGCTGGGGACAATTCAAGCCATTGTTGACAGACACAATTATTGAGTCCTTGAAACCAATCCAAGAAAAATACCAAGCGGTAACGGCAGATAAAAGCTATTTGGAGTCTGTATTGCGGGATGGGGGGGAAAAAGCTAGAGCGATCGCAAATCAAACTTTATCACAAGTAAAAGCTGCTTTAGGCTACTCGCTTCCTCTCTAAGTTTTCGCTTTTAGGTGTGATTTGCTATACCATTTAAGAAATTGAAATTCTTAATTTTATGTATCACACCCATAGCCACACAGCCTTTCGCAGAGCTGTACAAGCAGGTGAATTTCTAGTTACCGCCGAGGTAGCACCCCCGAAAGGGGGAAATCCAGCGCACATGATTCAAATGGCGGCGACTCTTAAGGGAAGGGTTCATGCTGTCAATGTTACTGATGGTAGCCGCGCCGTGTTACGGATGTCTTCGTTACTCGCGTCGGTGATTTTGTCACAAAATGGTATAGAGCCGATCTGTCAAGTTGCTTGCCGCGATCGCAACCGCATTGCTTTACAAGCTGATTTAATGGGCGCTCATGCTTTAGGTATTCGTAATATTTTAGCTTTGACTGGCGACCCAGTAAAAGCAGGCGATCATCCAGATGCTAAAGCAGTGTTTGACTTAGAAGCGGTGCGACTGCTGCAACTAATTCGAAAGATGAATCAAGGGGTTGATTACAACGAAAAACCTTTGACTGATGGAGCGCTAGATTTATTTGTTGGTGCAGCAGTAGATCCGCAATGTAAAAGTTGGTCGGGTTTACAAAGTCGATTTGAACGCAAAATCGAAGCCGGAGCGCAATTTTTTCAAAGTCAGTTGATTACCGATTTTGAGCGCCTAGAAAAGTTTATGGATACCATTGCCTCTGGCTATAAAAAACCGATTTTGGCAGGAATTTTTCTGTTGAAATCGGCAAAAAATGCCCAGTTTATTAATAGATGTGTTCCAGGTGTCAATATTCCCCAACATATTATTGATAGATTGGCAAAAGCCAAAGAGCCTTTTGAGGAAGGGATAAAAATTGCCGCCGAACAAGTGCAGATAGCACGGCAATTGTGTCAAGGTGTCCATCTGATGGCAGTAAAGCGGGAAGATGCGATCGCACCAATTTTGGATTTGGCTGGGATTTCTCCAGTTAATCAGTTGGTATCTAAGTAAATGAGATAATGGATTTTTTTATTAAAGCAGATGATTGTGACTATCTGCTTTTTTTGATGCGTAATCAGACGTGCATACACGATTTTTGATAAACTTTGAATATCCAATTTCCGCTTGACTAAATCCAAGTGCAAACTGACAAAATATTTTATAGCTTATTTCAATCTTTCCCCAGCATATTTTTTGCAATAATTGGCGATAATACTGTCAACGTCAACGCATATCAATTTGTTTCAGTCGAACTAAAAGAAACGGCTTTTAGGATTGATGGGGTATTCATGCCCACAACTGAAACCACAAATCAACCACTCTACTTTGTTGAAGTCCAGTTTCAATTAGACCCGACTTTTTATAGACGCTTCTTTGCAGAAATCTTTCTTTACTTGCGTCAAAACGAATCAGTCAATTTTTGGCGTGCTGTCGTCATCTATCCACAACGAAGTTTAGATCCAAGCGATCAACTACCGTATCAATCGCTGCTAAACAGTTCACAAGTGCAACGCATTTATCTAGATGAATTAGATACGGCGGAGAACTCACTTCAAGTTGCGATCGTTAAATTAATCATCGAAAGAGAAGAGACAGCCGTTGACAAAGGTAGAGAATTGATTTTACAAGCAAGGCAACAGCTAGCGGATGAAGCAACCAGGAAGCAAATTGTAGAATTGATAGAGACTATCCTGTTGTACAAATTTACCCGGTTAAGCCGAGAGGAGTTAGCAGAAATGTTGGGTATAGACGACGAATTCAAAAAAACAAGGATGTATCAATCTATCAAGCAAGATGGCTTGGAGGAAGGTAGACAGGAAGGTAAACAGGAAGCTAAGTTAGAAGCTATTCCCCGGTTATTGGCATTGGGGTTGAGTGTGGAACAAGTGGCGGTGGCTCTCGATTTAACGGTGGCGCAAGTACAGCAAGTAGCCCAGAATCAGTCTGGCTGATAGTGGGCGATTGTCTGAGTATTGCGCTTTATCTCTGGAAACACCGTGCTATATATTTCTTAAGCAAAGTGTGCAAGATATCAGTTAAAAAACTGGGTTACATCTTACCGTGTTGCAGCACTTGTTGTAGATGTTGGCGAATCTCTTGTGCGTGTTCAATATCAGATTGGCGCAATTTTTGGAACAACTCTACACAAGGCTGAGAACCTACTTGCTCTGCATCTTTGATGTAGGCATCGTAGGCTTTAACGGCTTCAGCTTTGTTGTGCAAAACGGTGACAAAATCATACTCCAAGTCGCTAATCGCTGTTTGAGACTGTCCGTTACCTGTATTTGTAGCCATTGCTTGATCCTCTTTTAGAATTTCTAATTAACTTTATACTCACCCTTAAAGAGCGATTCATCTTCCAAAAAGAGTATATTTCAATACGTCGGAAGTACCTTGCGAGTGTAGGTTATAGTATTCAGTGCGTAGGCGTAGCCCGTCGTAGACATCGCTTTCCAATTACCTCAGCCTTATTCAATCTCGTTTTTCCTTTACTGGTACGCAAAAAATAAGATCCCTGACTTATTAAATAAGTCGGGGATCTGCGGGTTCCAATTCTCACCAATCAAATAGAATTGCCATACTGCTAAAGAATTAGATTTGAAACTCAGAAATAAGCAAGTCGTAAGCAGCAAGTTAGAGTTTTACTGGCTCTACACATCTAAGAGGATATTTTATTAGTCAACATATAAATCAGGAGATAGGACAGACAAGGGAGAAAATTCTACCTCATCTCCCCACTCCCTATTTTCATTAGAATTTAGCCAAGCGGTTTATTTTCATCACATTGACGTGAATACTGGAATTCCAAATCATTTTGCCGTTCCCTACCTCCTCTATACACAACCGGACAAAACTTAGTGTTAGCGCTCATACAATCCATGTGTGGAGTTTTAGCACAGACTACGAGTAGTCCACCCAGAACAAATAACAAACCACAAATTGCAAGCGTATTAACCCAAGAAATTTCCAGCGCTCCATGAACTACTATTTCTCTTAGTAGAGATACAATTGTTACCTCAACCGCTACTCCCACAGAGATACTATGTTCTTGCAAGTAGACCATTAATAGCCGAAATAACTCGACTAAAATTAACACAAATAGTATTTTTGCAGTCACGTGTTTATAGTCTAGTGGCTGCATGAGGGCGATAGCTATTCCCCACAATTGGATCAGCATGACGGCAAATAAACCTAAACACAAGACAATCACAATCAAGTCTTGAAAGGCTTCCATGTTGCGAACAATTGAGTGCCGATCAAGCCAGCGATCGCTAAATAAAAATCGACTTTTCTGGCGCTTTTGCATGTACATTTTTCCAATCGGGACAAGTTCAGACAACACCAGCGAGTCAGCCCAATAGTTTTATGTTATGCAATATTAAGCGTTTGCGCCTCAGCGAGGTTTGTAATTTAAATTTTGTGCTTGTTGCAACAATTGCTCGGCATTTTTCGCCCACTGAGGATTCTTCTGAGAATTATATAAATCTCTAGCAAATTGCAATACTTGCACTGCATCTCCATATTGCTGTAACTGCATAAAAACTAACCCTGCACCATAATAAGCATTGGGATAGTTAGAGTTAGCTTCGGCTGATTTTCTAAAAGCTTCTAATGCTTCTTGTAACTTGTTTTGCTGAAACCAAATCGAACCGAGATTGTAGTAAGCTTCTGGATATTTCGGATTAATTTTTACTGCCTGATTAAAAGCATCTCTTGCTTGATCGAGCTTGCCTTGTTGAAGATAACACATCCCTATATGGTAAGGAGGCTCCGGTGCATTTTTGCTATATTCTATGGCTTTTTTAAAAGATGCGATCGCTTTCTCACAATCTCCTTGCTGCTCTCTTACTAACCCAAAATTATAGTGGGCAAATCCTAATTTTGGATCGAGTTCTAACGCTCGTTGCAAATAATCGTTAGCTAACTGTAAATTATTGCCTTCTAACAACGCACCACCTAAATTAGCAAAAGCTGGAGCAAACTTAGGATCGGCTTGCGTCGCTCGATAAAATGCGTCCGCAGAGGGTTGTAATTGTCCTGTTTGTCGGTATGCTAGCCCTAAATTATAGTACGCTGGTGCTAATGTTGGATCTAACTTGGCTGCTTGTTTAAAGGCTGCGATCGCATCTTTTACTTTGCCCGCCTGAATTGCCTGTAAACCTTGATTTAGCCAGTCTATGGCTGTTTTCCCATTAGATTGTGCCAGCTTTGAAGGGACAGACCCAGAGAGAGAAAGAGAAGGCGAGGGAATGCTAACAACCAACAAAGTCAAACTGACTAACCCTGCTATGGGATATTTAGAAAATGATAATCTCATTGATTTTCTGATTCGCAACACTTTCAGTTAAATTTACTTCATAAAAAGTTATTTATAAAAATTTTAGATTCGCTATTAATCTTTACTAAGATTAACTTTTATTAAGCTAAATCTTACGACAGGCTACAATTTTTTTAACTTTCGATTAAAAGAAGGATAATAACAAATTAAAGAAGGGGTAATTTTGACTCCAGAGAACCATTTTTTGATCAAATAGAATTCAGGAGTCAGGAGCCAGAATTCAGAATGAATTCTGTACGACACAACGACCTGCGGTAGTTGAGCGTAGCCGAAACTCAGTGCATCGCTGGTGGATGAATAAATCGGTTTAAGACGCTCGCGGACTCGCTACTGTCTTGATTCCGAATCCTGTTAGCGCTAGCGGGGCGTTTAGCTCATTCAGAATAGCTGGATTCTTCTTCAACCCTTGATATATACGGAATCATGCGGTTATAAAAGACTTACCGCAAGGAGGATTTTATGAACGAAAAAGTAAAATCGGGTTCGCGGAATGTTGCAATTGTCGGGCCTTATTTAAGTGGAAAAACCACTTTACTAGAAAGCTTGTTATTTGTCACAGGGGCAATTTCTCGCAAAGGCAGCATTAAAGACAGCAATACAGTGGGAGATAGTGCTGCCGAGTCGCGCGATCGCCACATGAGTGTAGAAGTCAGCGCCGCTAGCACTGAGTATAACGGCATTTGCTTCACTTTTATTGACTGTCCGGGAAGCGTAGAATTTGCCCAAGAAACGTACAATGCTTTAATCGGAGTGGATGCGGCAATTGTAGTTTGCGAACCCATCCGCGAACGAGTCCTCACCCTCGCCCCTCTATTTAAATTCCTGGACGATTGGGAAATTCCCCACCTCGTCTTCGTCAACAAAATGGATCGGGCAAATATTCACGTTTTAGAAACGTTACACGCCCTCAAAGCAGTATCTAGCCGTCCCCTGGTAGCACATCAATATCCCATCATGAACGGGGAACAACTCACCGGCTTTATCGATATGGTGAGCGAACAGGCATATAAATATCATCCAGGCGCACCTGCTGACCCCATCCCCTTCCCCGAAAGTTTAAAAGAAGAAGAACATGAAGCACGGGCAGAAATGCTCGAAGCTTTAGCAAATTTTGACGACCATTTACTTGAAGAACTTTTAGAAGATATCGAACCACCCCAAGAGGAAATCCTTAAAGATTTAAAAATGGAATTAGGGGCAGATTTAGTAGTCCCCGTTTTCTTTGGTGTGGCAGAACAAGATTATGGTGTTAGACCTTTATTAGAAGCCTTGTTACGGGAAGCACCTGAACCAGAAGCCACAGCAGAACGTCGTTTAAAAAACTTAAAAGGTGATACACCTCTAGCGCAGGTATTAAAAACTTACTACACTCCCCAAGGTGGCAAACTCTCTCTCGTGCGTGTTTGGCGGGGCAAATTAACTGATGGCATTGTCCTCAATGGCATTCGTACTGGTGGAATTTACCGCCTCATGGGACAACAACAGCAGTTTGTTAACCAAGCTAATGCTGGTGAAATTGTTGCATTGAGCCGTTTAGAAGGAATCAAGACAGGCGATACAATCTCTATAGAACAACAGTCTGCAATAGAATTACCCAAAGCTACACAGTTGGAACCTGTGTATGCCCTCGCCATTACACCAGAAAAGCGTAACGATGAAGTGAAACTCAGCAGTGCCATTACCAAGTTATTAGAAGAAGACTGTTCACTTGCTTGGGAACAACACGGCGATACTCACGAAGTAATCTTGTGGGGTCAAGGCGAGATTCATTTACAAGTTACTTTAGACAGACTACGCCGCAAATATAACTTGCCGATGACAACCCATTTACCGCAAGTGCCTTACAAAGAAACCATTCGCAAAACGGTGGCTTCAGTTCATGGACGCTACAAGCACCAAAGCGGTGGTCATGGACAGTTTGGTGATGTTTTTCTCGATATCAAGCCCCTACCACGCGGTACAGGCTTCAACTTTAATGAAACCATTGTCGGCGGCGTGGTTCCCAAACAGTACATTCCTGGTGTGGAAATGGGCGTGCGGGAATTTCTCACACATGGGCCTTTGGGCTTCCCAATAGTCGATTTGGCAGTAACTCTGACTAATGGTTCGTATCACAACGTTGATAGTTCCGAACAAGCCTTTAAGCAAGCTGCGCGATTAGCAATGCAAACGGGGATACCCCAAGCAGAACCTACGCTGTTAGAACCAATTCTGCGGGTAGAAGTGACTACACCGAGCGAATTTACCTCCAAGGTGCTGCAACTGTTGAGTGGTAGACGGGGGCAAATTTTAGGCTATGAAGGTAGAAATGATTGGCAAGGCTGGGATAATGTCTCGGCATACTTGCCACAAGCAGAGATGCAAAACTTTATTGTAGAACTGCGATCGCTCACTCTCGGCGTTGGTTCCTTCCACTGGGAATATGACCATCTCCAGGAAGTGCCGGAAAAACTCGCCGAACGCGTCATTCACAGCAATGGCAATAGTGGTAACGGCAACGGCAAGTAATTTTGGATTTTAGATTAATTTAAAATCAACGCCCTGCACCTTTGAGTGCAGGGCTATTTTTTAGTGAATTAGGACTTACGCAAAAACCCTCTAAAACTCTCATTCCTCCGTGAACTCTGCGCCCTCTGTGGTTCGTTTTCCGTTACCCGTGTGTAAATCCTATGAATATTTAATACACTTTGAACGTTATGAGGTGTGATGACAAAAGAGTTCCGCCCACAATAAACCGGGCAAAGCAAAATTATAGCTTGCTGCTCTTGAGGGAAAGTTTTATAAAAGCATCTGGGAATTATGTGATTAAGTCTATCCGTCTTAACTACACAGAAAAACTCATGGGTTTTATAATCTCTCTTCTAACTAGCCTGATTGGAATCCTCGTTTATCTCAATACAGGTAGGATCTCTGGCGAAAAGTCACGTTTAGCAATACGCACAATTACGATATTGATTAGCAGTATTGCAATACTAAATTCTATTTCTAGGCTTTTGGTGATTGTCCCACCAGGCAATATTGGTGTCGTCAACTTATTTGGTGAGGTTTCCGAAAGCACTCTTAATCCTGGTGTCCACTTCTTGAACCCCTTTAACAAAGTGTTGAATTTTTCCACTCGCATTAAGGATCTCAAGGAAAACATAGATGTAACAACCCAAGAAGGTTTGAGTCTAAATCTTGATGTCAGTCTTCAGTACAAGCTCGATCCCCAGAAAGCAGCCACAGTATATAAAACCATTGGAACTGATGAAACACAACTGGTAATTTCCAGATTCCGCTCTACCGTTCGTGCTATCACGTCAAACTACCCAGCCAGTGCTATTTACTCTACCAAACGTCAAGAAATCGCCCAAAAAATTGACCAACAACTCACCCAAGAGATACCCACTTTGGGTTTCATCGTTGAGGAAGCTCTTTTACGAAACGTCAAAATGCCTGATATTCTACAAGTTGCAATTCAAAACAAACTCAAGACAGAGCAAGAAAACCAGCAAATGAAATTTGTTTTAGAGAAAGAGCGTCAAGAGGCAGAACGAAAGCGTATTGAAGCTCAAGGCATAGCTGATTATCAAAAAATTATCTCCGTTGGACTTACCAACCAAGTGCTACAATTACGAGCGATTGAAGCCACAGAAAAGCTAGCTCAATCAAATAATTCTAAAATTGTAATTATTGGTTCTGAAAAAGGTGGAGCGCCTATTTTGATCCAGCCAGAAACAGGAACTTCAAGACCCTAAAATTTTCTGATTAGCGATCGCTGCGGCGTTGCTTCCTCCTACATATCTCTCTTTCGGCTTCCCACCTTGCTGCTGGCTGAATGATACAGTATGAGCGTTGCTAGAAACTGATGACTATGAGCGGCGATATTGTCGAAAAACTCAAGAAAGCTAGTACTGGCTTGTTAATGATGAGCGAGTCAGATTACCCTTTTGAGGTTGTTCAATGGGAAGGTGCTGCACCTGCAACACAAGAGAAAATATTACAGCTAACAGGTTCTCAAAACCTGCCAGTCGAAGTAGTAGAGTTGGACTATTTCTTGCGTAATTGTGCATTTGAGCAAGAGTGGCACAATGAATTACAGAAAAAAGATGTTAAAAGATTTCAAACACTTATGCAGACACTTAAAGATAATCTTAGTGACATCAGCGTTTATCGTGTTGGACAAATAAATATTGACGCTTATATCATCGGACAAACTCAAGACGGTGACTTAGCTGGAGTAGTAACAAAACTGGTTGAAACCTAGTATACAGGTTGGAAAATTCTTTAAATAAAAGCCTAGCTGCACAGATGGCTAGGCTTTCTCGTTTTTAAAATTATTCCAACTTATAAATTGTCAACTCGCGCTTCTATTACAGACTGAATAGATGTTGAAACTTGTGAGAGAAAATTGTATCCAGTTAGGGATTCTAATGAGTCAACACTAACCCGATAGTTTCTCCAATTCGCTGTTCGCACGCCTTGGGCGTTGGGAATATTGACAGCAATAACTCTCGTGCTGGTTGTCACGCCTGCAAGACCTGAACCAGGAGTATTCAATACAACAAGAATTTTCCAGGTTCTGTTAGGGACTTGAACCCGTCCATTAGCTATTGTATAGAACGTTCCGTTAGAACCAGTACCACCCATCCCATATCCACCAGATATGATGTAGAGTTCTTTACCCTGTCCTACTAAAGTTCTGGCATAATCCTCTAAGTTTGCCCAAATTCCCTGATTGTTATCTGGGGCTTGAGCAATCATATTGCTCATCAAAAAGGTGGCAGAATTATTAGTAACACTACTAGTCCTGTCAGCGCTAGGTGTCATGTGACCGCGATCAAACCCACTTCCGCTAAAATCGGTAGATTGAACTTGATAACACCCTGAAGGAAGTGTTGTATCAGCCCGAAAAGTATCTTGTCTTGGTGTGCTACCTAACCAACTATTATTTAACTGCCAAGACACCCAATTTGGTCTACCTATTCCGCAGTTGTAACCAATTACATATTGTGGTTTTACCAACAAGTAGTTATTTTGGCTAGAAGTTCCAGCGTTGCTAGGGTTGCCAAGAGTTAGGTGAACACTTACTGATGACTGGGCTGGTACAATCTGTGCTAACCCAATTATGAATAGAACCACCGTCACAAATGGCAGTAGAAACTTGAAAATCTTGATTTTTTTCACGTTTTTGTGCTTTTGATTACCAAAACAGTGTCCAAGTTCTTCGTTTCAATATCAAGTATTCAGTGATACAAAAAAAATATTTTTTAATGATAAATATGTAGTGACACAATAGCTAGAAATCTTTATTCGTAAGAGTTAACAATTAAAAAACTGGCTTTCGTGATGAGTGATGGCTTAAAATTTTGCATCTCTACACCAAGATTTATACATCTAATTAGCAATGCCAATCTTTTTTCTTAAAGAAAATTTTATTCACACCATAAATTAGGGCGATGCCTGCGATGGAAAGCCACGCACTCGATCGCCTTAATCTCTAATTTTATGGTTCACTGGCGGCTATTTAATTTCCTGAAAATTCTCAATTGTGAGATATATTTCTTCATCAGCTATCTGACTGTTGTAATCTATCTCAATTTTGGTTGGATACCCGAATTTAGGGCTGTAACTCACATTCAGGCTGTAGGCTTGACGGTTGATAGCATCTTGAATCACATTAAACAGCTTAGGAATTGTTTTGTAGTTTTGAAAGAATTCTGGATTAACTGCTTGACCTGTAGCTACAGAAGTGATAGAAGTTGTTTGACCATTACGGACTTCAATGACTACTGGCCCCCTAGCGTCTGGTATACAAAAGCATCCATTACTAAATGTATAGCGATAGTTGGAAATATTTTGCTGATTCCACAAATAGCGATTAAATTTTAATCGTCTTACATCCAAATTATTATTTTTCGTTGACGATTGTGCTATCTCTATGGGAGATTTTGACATTACTGGTAGGTTAAGACCGAAAGATAGCAATAATCCGGCACTGATAATTATAGGTAAACGCATATCAATTCATTTAATTTCAAAAGTGCTATATACATTAATTCATGTACTTGTTTAAATAGACTTTATCTTTTGATTAAAATCTATCTATACTTAGCCAAGATCAAATAACAAATTTATTCTTCCCACAGCGATCGCTTACAATCGCATTTATCGCTTGTAACTTAGTTTTATGGAAATCGGTGCGATCGCAGATGTACGAAAATCTTTTCTCTATGCTGTAAAATCTTTACTGTAAAAAACAGATTTTTTGTTTCAAGGATGAATGAATCACAAACTTGGTATATTGTCAAGCATTCTGCTGGTAATTGCGAAATCGTCCCCAGCGACAAAATTTGCGACGATAATTTAGAGATTAAAGAAACTATAGAACAGTGGGGGCCTTTTAGTTCGCAAGGAGAAGCGATCGCTCGGCGTGTTGGACTTATTAGGGCTGGAAAGTGCCAACCAGTTTAAGTTAGGAGTTAGAAATGATGGTTTTTATTCCTAAATCCTTACTACTCACTCCTAACTCCTAACTTTATTCTTAACTCTTCATTTTTCTGCTGTGGCTGTGCCCTTAGCAGCAATCTTTTTACCTATCACTTCTACTGCTTTAGCGAATTGTGGGTCTTGTAGGGTAGCGAGTTTATCGCGTTCATGGAGCCATAATTCCTGCATCTGCTCTTTGGTCAACTCTACCTTCACATCTGGATTAATACCTTTGTGATTAATATCCGTACCATTAGGGGTATAGTAATGAGCAATTGTTACCGCCAATCCTGAGCCATCTTCTAAGGGACGTACCGATTGCACGAGTCCCTTACCAAAGGTTTGAGTACCAACCAAAGTAGCACGCTTGTTGTCCTTCAAAGCCCCTGAAAGGATTTCACTCGCACTGGCTGAACCTTTATCTACCAGCACCACCAAAGGTTTATCCGTTAAGGCGCGTCCGTTTGCCTCTTCTTTTTCTGCCTCTCCTTGGCGTTCAACGGTGGAGACAATCTTACCTTTATTTATCCACATCCGGGCAATGTCTACACTGGAGAACAGTAAGCCACCAGGATTACCACGTAAATCCAGAATATATCCAGCTACCTTTTTGCTTTCTAAATCCTTGATAGCTGTTTGCATTTCTTTACCAGCATTAGCGCTGAACTGGTTCAGGCGAATGTAGCCAAGATTACCTGCTGGAGTTTGTTTTTGGGAATATTTAACTGGATGAATTTCAATCCGCGCCCGTTTGATGTCTAATTGTTTTACCTGACCGTCGCGCTGAATCGTTAGGCTAACTTGCGTTCCGGCTTCACCTCGAATTAGGGATACTGCTTGATTAGTATCCATCCCCTTGGTGCTTTTGTTGTCGATTTTGAGGATGACATCTTTTGCCAAAACACCAGCTTTAAATGCTGGTGTATCTTCGATTGGCGCAATTACAACCAGTTGCTTAGTTTTTTCATCTTGACTGATAGTGATCCCAATCCCGATCAATTCTCCAGAAGTGTCCACTTGCATATTTTTGAATTCTGCTGGGTCCATAAACCGGGTGTATGGATCTTCCAGCTTTTTCAGCATTTCCCGAATAGACTTATAAGCATCCTGGGGATTACTGTAGGACTTGCTTAAATACTCCTTACGAACAGCCTGCCAATCTACCTGATTGAAAGTACCATCTACATATTGGCGCTGAACAATTTGCCAAACTTCATCTACTATTTCTTTGGGACTTGCTTTAAATAAAGCCTGACCTCGCGAGTGAATGCCAAGACTAGTAACTGCGATCGTGGAGAGTGTCACCGCCGTAGCACCCAAAACAAGCCTACTTTTTGTAATCACCATAATGACAGCTGCGTCAGAGGGAAAATATATAGTCAGTATGCTCAATCTAACACAGGCTTCCACTGTACAGATCGAGTATGTATTCTTAATTTAAACAAAATACTTGACAATCCGGCGACCTTGGTCGTTATCAATACAAAAGTTTTAAGATTGGGGATTGGGGATTGGGAATGGGGAATGGGGAATGGGGAATGGGGAATGGGGCATTGGGCATTGGGCATTGGGCATGAAGAAGAGACAAAGGATACAAGGAAGAGGGGGAGACGGAGAGACTTGTTCAATAATTCCCCCTTGTCCCCTTGTCCCCTTGTCCCCCTGCCCCCTGCCCCCTGCTCCCTCTCCCCTTAAGGTTCTACCCAGCGTTCATCTGCCTTAATGAGGTTAATTAATTCCTCTACACCTTTGTCTTCTGGGACTTTTTTAATTTCTTCTCGACCACGATATAAGGAAATGTAACCAGGTGTTTTGCCAACATAACCATAGTCGGCATCTGCCATTTCGCCGGGACCATTGACAATACAACCCATAACTGCTATGTCTAACCCAGTCAGGTGTTTAGTGGCTTCCCGGACTTTGTGTAACACTTCTTCTAGATTAAACAAAGTACGCCCACAAGAAGGACAAGCGACGTATTCCACCATCGTTTTTCGCAATCCCAAAGCTTGGAGAATGCTGTAACAGACGGGAATCTCTTTTTCTGGTGCTTCTGTGAGTGAGACGCGAATTGTATCGCCAATGCCATCAGCAAGTAGGGTAGCAATACCGGCCGTAGATTTAATTCGCCCATATTCGCCATCACCAGCTTCGGTAACGCCTAAATGTAGCGGATAATCCATACCCAGTTCATCCATGCGCTTGGCGATCAGGCGATAGGCGGCTAGCATCACAGGTACTCGTGAAGCTTTCATGGAAATTACCAAGTTGCGGAAATCCAAGGATTCACAGATGCGAATGAATTCTATGGCAGATTCCACCATTCCTTCTGGAGTGTCACCGTAGGTAAATAGCATCCTCTCGGCGAGGGAACCGTGATTTACCCCAATTCGCATTGATTTACCTTGATCTCGCAAAGAAACTACTAAAGGTTCTAGAGTTTCGCGGATTTTATCGCCAATTTCGTCAAATTCGGATTGAGTATACTCGGTTCGATTGACGTTGGGCTTTTCAAAGACATACAACCCCGGATTAATCCGCACTTTTTCTATGTGCTTGGAGACTTCCAGGGCGATTTTTAGCCCATTATGATGGACATCAGCCACAATGGGCACGTCTTGGTAAGTTTTTATTAATTTTTGTTTAATTTCTGCTAAAGCTTTAGCATGAGCCATACTCGGCACTGTAACACGGACAATTTCGCAGCCAATTTCGTGCAGACGACGAATACCAGCTACGGAACCATCAATATCAAGGGTGTCTTCGTTAATCATTGACTGCACTACAACGGGGTAGCCACCGCCAATGGTGACATTTCCTACCTTTACGGGACGGGTTTTACGCCGCTTGATAGTTGTATCAAAGACAGGTTGACTTGATGCAGTATTTGAAGTATCTACTATGGGCAGAGTTTGCATAACCTGATCGGGTAAATTTGCAGTAGCTAAAAATATCAGATTTGATAAATCTCTGTTTCCCAGATTGCCACAGCTAGTGGCTCTTTTGGAGGATTATGTAGAAAAAATTGGAGAATTGAGTCAGGCAAAGAATTAAAAACTTTTCTAACTGAGCAGTGTTAGTGAGGTTTAACGACGCGATCGCTCTTTTACTGAGTTATAAGTACTACTAACAATGGCAGTAATTATTTGTCTGGTATATTTTCGCTGTTGTGATAGTTGTGTAGCGATGTACCAATACGTTTGATACTTTATCAAGATAACTGATTTTGACCTTTGTAAGCTTAATGCCTTTGGCATATCGCAACTACGGCTTACCGAAGCGATCGCGATCGTGCAGTTCGTCAAAATCGATGATTGGCCCCTTGGGTACAATTCGATTTGGATTAATCTCGGTCATACTCATGTAATAGCCGCGTTTAGTATAGTCTAGATTGCACGTTGCTTTGAATGGCCACGCATCAGAAAGAGTTTCGCCTCCTGCACCCTGCCCAAATAATGATTACTACCTGAGATAGAACTGGCGTTAGCCATTTGGGAAGACTAAATATGAAAGCCTTCAAGATTTAGTAGATGGTTAGTATTCCTGGATACCACGTAACTGAAGAAATCTCCAATGGTTCGAGAACCCTAGTTTATCGAGAGTATCGAGAAACTGACTTTTCCCTCAAAGATGATTTTGGTTTGGATCGGAGGCGATATGTCGGGTATTTACAAGAGTTTTTAGCGATCGCTCGAAAAATTATAGTGGAAAAAAATAGTGGTTCGATCCAATGCGACTCTTCTCCAGGGCAAGGTACGGAATTTGAGATATTAATTCCAGTTCAACAGTCAGCAGGAGAAACAAGTAATGCATAACACAGAATTCGAGCAAGAAATACTTTTTCTTCGTCAGCAAAATGCTCAGTTACAGCAACAACTGGCAAAATCCACCACAGAATTCAGTGCAGAAATCGCCCAATTAGAACAGAAACTTAGAGAATCAAAACAACTATTAGAAAGTAATTGCCAAGCAGAACTAACCTTCAAGGCTTCTCAAGCAGAATTACTAGCATTATTTAACGCCATACCAGATGTGATTCTCATGCTTGATGCCGAAGGACGTTACCTCAAAATTGCTCCTAGCAGTGCGCCTTTACTATACCAACCCCCTGTGGAACTAATAGGTAAAACCATGCACGAGGTTTTACCTTCTGCTTTTGCAGACTCTTTTCTCAACTGCATTCAACAAGCACTAGAAACCAAGAAAACTTTCAAAATCGAATATAGCTTGCCCATTGGTGATCAAGAAGTTTGGTTTGAGGCGAGTATTGCGCCAATGAACGAGGACACTGTTGTTTGTGTAGCTAGGGATATTAGTAATGTCTACAACGAGCTTCGTTTACGCAAAGCAGCTGAGGCAACCTTAAGTCAACAAGAAGATCAGTATCGCAGCATTTTTGAGACTGTGAATGATGGCATCAGTGTTGTTGATTTAGATACAGGTAAGATTGTCGCTGCCAATCCCGCTTTTTGTCAGATGCATGGCTATTCTCAAGCAGAATTTTTCCACTTAAGTCCTACAGATTTCATCCATCCCGATTCTTTTCAGCAATTTGCGGAATTCATCAACACAATCAAGATGGGAGGTGAATTTCACACTCAGGCTGTAGATATTCGCAAAGATGGCACTTATTTTGATATAGAAGTTACAGGCAAACTCTTTAACTACAATGGCAAACCCCATGCACTTTCGGTAGTGCGAGATATTAGCGAACGTAAACTTGCTGAACAAGAGCAAAGAAGACTGCTAACTATTTTAGAAGCCACAACTGATATCGTCGGTATGGCTGATGTAGATGGAAATAATTGCTATCTAAACAAAGCAGGGCAGAAGATTTTAGAAATTCCAGCCTCAGAAACCAACAAATTTCATATTAGCGAAGTTACAGGACTATCAATATTAGAAAAATTCCAGAATGAAATAATACCTATTGTAGTTCGAGAAGGGATTTGGTCTGGAGAATCTATATTTCGCTGTCGCAATGGTGAAGAGTTTCCAGTTTCCCAAGTGATAATTGCCCACAAAAATGAACAAGGCGAAATAGAATTCTTCTCAACTATTGCCCGTGATATCCGCGATCGCCAACAAATCGAAGCCCGGCTTAGACAACACGCAGAAGATTTAGCCCAAACTCTTCAAGAACTCCAACGTACCCAAGCACAAATGATTCAGGCAGAAAAAATGTCTAGTCTGGGTCAACTCGTGGCCGGAGTCGCCCATGAAATCAATAACCCTGTCAATTTTATCCACGGTAATCTCAGCCATCTTGAAGAACATACTCAAGATTTATTAAGGTTAATTAACTCATATCAAATCATTAACCCGCCAGAATTTCAGAACGGTAATTGCTACTCTGGTGAAGCAAGCTACGCATTAGCAGAGCGACTCAACCCACTGCTGACTTTATGCCAAGAAATTGATCTGGAATACATTCAGCAAGATTTACCAAAAATCTTGAATTCAATGAAAGTGGGAACTCAACGCATCCGTCAGATTGTCCTGTCACTGCGTACTTTCTCGCGCATGGATGAAGCCGAGTTTAAAGCTGTAGATATTCACGAAGGCATAGACAGTACCTTAATGATTTTGCAACATCGCCTCAAAGAAAAACCAGAATTTCCCGAAATTAATGTCATCAAAAACTACGGCAGCTTACCTTTAGTAGAATGCTACGCCGGACAACTGAATCAGGTGTTTATGAATATTTTTGCAAATGCTATTGATGCCTTAGAACAAAAAACAGACAATGAAGTTTCTCCACCCACAATTACCATTCATAGCACGTTAATAGATTCTCATTGGGTCAAAATCGCGATTGCCGACAATGGTTTAGGGATGCCAGAAGGAGTTGAAAAGCAGGTTTTTAATCCATTTTTTACCACCAAGCCTGTGGGTAAGGGAACAGGTATGGGAATGTCTATTAGTTATCAAATTATTACCGAAAAACATGGTGGCAAATTGGAGTGTTACTCAAAACCAGGTCAAGGAACAGAGTTTGTGATTAAAATTCCAATTCGGCATTAGATAGGCAATAGTCAAGAAGCCTCTTTGAGCTATACGGAATTTTTTCAACAATCAGATATGAGTTTTATATTAATCAATCTAGTTTTTAATTCAGAGTGAATTAATAAAAATGCGATCGCTATTGCTGAATAACCTATTTGAGCGATCAGAAAAAAGCAAAGTTAACCTTTTTTTAACGAACCACAGAGGCGCAGAGAACACAGAGAGAAGGAAGAAATGCTTAACTGAACTATTGGGGTAAAGGTTTTTCTTTACCCCTTTTCTCTTTGCCTTTTCCCCAAAACTCGACAAGTATTGATTGCCTATTGCCTGTTACCTATTGCCTTATCCCAACGACAATTTACGCCCACTTACTTCTGAATTTTCCCCCTTCGGGAAGGGGGTTAGGTCTATTTGCATACTTGTACCTCACCGGATTGAAAATGGTTATAAGAATAAAAGGTGTTATGACTGCCGGACTACAAGTCGGGCAAATAACCCTTCTTCTGCAATCAATTCTGAGAAATTACCCGTCTGCACTACATTACCTGCATCAAGAACATAAATGCGGTCTGCATGACGAATTGTACTGAGGCGATGGGCAATCACCACTCTGGTAGCATTTAATTTAGCTAAACTTTCAGTCACAATTGCCTGGGTGCGATTATCCAGAGCGCTGGTTGCCTCATCCATTAAAATAATTTTGGGCTTTGCAACTAGCGATCGCGCAATCAATAATCTTTGCCGTTGTCCCCCAGAAAGATTAGTACCACCTTCAGCGATTATAGTGTGCATTCCCATCGGCATTTGCTTGATATCATCAGCGAAGCCTGCCATCTGTGCAGCTTCCCAAGCTTCTTCTAGAGAAACCAAGGCTCCGGCGGTGATATTATCAAAAATTGAGCCAGTCCCAAATTTGCCATTTTGCAATACTACTCCCAACTGCCTGCGTACAGCCTGAAGTTCCAAATCTGCTAAGTCTTGGCCATCATAGTAGACACTGCCTGTTAATGGAGTCTCAAATCCCAGTAACAACCGGAATATCGTTGATTTACCACTTCCAGAAGGGCCAATAATCGCCACAAACTCTCCTGGTTCAGCATGGAAACTAACATTGTTGAGAATTAAGTTGCCATGTTCCGAGTAGCGAAAACTCACGCTTTCTAGGGCAATACGACCACTTAATTGACCAGGGTTAACTTTGGTTGAGCCATCTTCAGGCTGCGATCGCCAAATCGGTTTTGCCCGTTCCCATATTGGTACAATCCCCCAAATCTCAGATACAGTATTGCTCAGGTCAATTATCCCTTTGATGAAAATTGTCAAGGCATAGTTAAAAGCAACAAATATACCAAGTGTGAGGCGTGGCTGGATCAACAGCATCGCCAATCCGAAAAGCAATATAGAACTGACTAAGGGTAGTGCTTCATTGAATACAGACATACCATCTTTAATCTGTTGCCAATTCGCTTTTAGCCGGATTTGCTGGCTATACTTTTTTGCCCAAGCCGCAAATGCCCGTTCTTCTGCCATTGCTACTCGCAGTTTGGCAACACCGTTGATTAGTTGGACAGTGAGTCCCTGAATCGCGCCATTGAGTTCTTGCTGTTCGCGGGATTTCTTTACCAAGCGGAAACTTGCAACTGTCGTAACCACGGCAGCAAAGATTGCTAAACCCACTCCCACCAGCGCTAATTGCCAGCTGTAAATAAACATCAACACTAAATTGAGTAAGGCAAAAACCCCACTCAACAACGTTTTTTGGGTAGCACCGCTCAGTTTTTGATGAATTTCCCTCACCGCCATAACGCGGTTAACTAAGTCTCCGGCAGTATACTGACGAAAAAACCTCGGACTTAATCTCAGCAGACGATCCCAAATAGCTGGCTGCAATACGCTATCAGTGGCGCTTTCAACTCGGAGGATAATAATACTTTGGGCAATTTGAAAAGCTAACTGTCCAAAGGCAACTGCAAACATTACTAATCCTATTTGCCATAGTAAAGCGCGATCGCTATCTGGAATGGCATTATTGATTAAAATTGCTGTTGCTTGTGGTGCAACCATTCCCAATATCGTCCCCAGTAGCCCCACTACTAAAATACTAGCGATATCTTTTTCATAACCTTTAACCCCAAACCGAAGTAAATCGATGGCTTTGAGTGCAACTTGGGGCAACGGTCGATACAGAACGTAGGCAGATGTTGTCAGTGTTTTTGCCACTGCCTCATTTACGGGGATGCGAGTTCGCGCAACTGGATCAAAGATCGTATAATCCCGCTTATCTGTGGGTAACAAAGCTACTGGGCGCTTTTCTAATTGAGTATAAGCTAACATCGGCCCTTGATCTTGCCGCCACCAGCCACTTGCCAAAGTCACACGCCGGATACGAATTTGCGATGATTGGGCGATCGCTGCTACAGGGTCTTTAATAGAACTAAAATTATCTGCTGCTGGACGAATCTCAATTCCTAATGTCCGTCCAATTGCTCCCATTGCTACCAATAGAGGCGGTCCCTCTTGAGATAAAGCTTCTTGCTGTGGTTGCAATACTGTTGCTAATTCAGAGAGTGCGCCCTCAATTACTTGCTGATTAAGTTGCTCTCTTTGCTGAAACTGCCGAAATTCTGCTTCTGCTTGTTTGTTTGCTAGCAAACTCAAGTAGTGAAAAAAATAAGTATGTAAACATACCAAGCTACTGAGTATTTCTTCCTGACTTGGGAAATCTGCGGTTGTTAATACTTGTCCAATAACTGCATTTTCTGCCTCCAGCCACATCGCACTCGTCAGGGGAAAAGCTGGCGAGGTGGGATTCAACGTTAGTTCCTCAACTCCCATCCAGCTAACATTACCTTGCTGCAACTTCACCCACACAAGTGTTTGTTGCCACAGATGTAGTGCCTCACCAGTGGATAATGAAAAATCCTGTCCCGATGTCTGCACAATGTTTAATGGCGTTGTCAAAACTGTTTGCTGGGAACTAAGAGACTGACTTAAATGATTTACCCAGCCTTCTAAAAGTTCTATAGCTTGAGAGTCAGCCGTCCCGATTCCCTGAACCAAATCAACCATTGACATCTGGCATAATTGAGTAGGTTCAATTGCGATCGCGATAAAACTCCACTTGCTTTCTTTTGGTAACAAAGCTGCACTAAACAATGCTTCTCCAGCGTTGACATGAAACAGATAGCGGCGCTGCTCCTTTAGTAAATTGTTTTTAACTCTAGTCGCAAACACTGCTAATGTTCCAGACTCCACTATCCAGACAGTTTCTGAGTTATTCAACAGTAATGATTCGTTTGCTTGAAAGGAGTACAGTTTAGAAGAAGGATTCACCTGCGGGCTACTCATTACTCAATTAATGAAATATTTGATGGGCTAGAAGTCAATACAGTTCAGTTAAGCATCTCTTTCTTCTCTCTGCGTTCTCTGCGCCTTGGCGGTTCGTTAAAAAAATGACTTTGGTAACAGAGTTTTAGCCTTAACTGAACCGTATTGGGCTAGAAGTCTTTTGCTATAACAGTATTTTTATCTAGTACATAGCGTTCTATAATTAATAATTAGCTTTGTAAGTACAACTTTATACAAAAGCACTGCACGTTACTACGTAAAGTTTAGCATTAAAAAATACTATTAATGTAATTCGATACACCCTGATGACCATCTCCAAAGTCTTGTATAAATTCATCAGTTACTCTATTTGCACAACTATCTATCTCTTCGGAAAGTGAATTTTGATGCAGTATCTGATGCGCTGATTTACGCAAAACCTCAAATAATTTAGAACTGTAATCAGAGTCTTCGCTCAAGAAATTCCACAGTTCTTTACCAATCAAAGTTTGCATTTCCCAATCAGGCAGTATTTGTTTTAATAGACCAATCGTTACTGTTTTGCTTGTTCTTTTACCATAAGTAAATCCTATATACGCTTTATCTCCTTCTTTAACTTTTTCTTGAATTTTTTCAGCCCAGTAAACTACTTGGTCTTTATCCATATTGTTTGGGCCGCTTTTTATTTGCAGCCAAAATTTTTCACCATCACTCGTAGTTTTAACCAAATCCCATCCTGATTTATTAGGAGCTTTTTCAACAGTATCAGAACTAGTAAGTAACAGGTCTTCTATAAAAAATCCCATAGATGTAACGATTGAGCGAGTAGCCGCCATATAAACATTTAATCTAACAACTGCATCTGGAGTATCTAAATTAAGCGCTCTAATTAAAAATGGGTTAGGATTTAAGTTCTTTAAAGATAGGTTTCTAACCATATTTAGTTGTTTTTGGGTGAATACCCTACTAATAATGGCTAAATAATTTTCGGCAACTGTAAGTTCTGCTGATAAAGAGCCTGATTCCCTATATATAGACAAATTAGTAATTTCTTCGTCTGTTAACTTTAAAACGCTTTTACCAGATATACTCTTGAGGTTTTTGATATTTTCTTCTTGAAATTCTAAGAAATCTTTTATATCTGCAAAATATGAGGCAAGAGAACGTGCTTTGTTGAGTGTAAAACCTACCTCATTTTTTAGAGCGTATGCTAACATTTCATGAAACTGTTCGGACACTTTCTTTTATCCTAAATCTAAATAAAATAAATCTTTAAAAATTTCAACTAAAAAAGTGAAAGCTGTTCAAAAACATTTGTTGATTCTGGTTTTTCATTTTTGATTATTTTAGATAAATATTGTCCTATTGCGTGAGACAGTTTAACCGGTACAGAATTACCTATTTGTCTATATCTAGACGATAGAGAACCATAAAATACCCAAGTATCAGGAAAAGTTTGAATTCTTGCATATTCTCGTACACTTAGAGGTCGTAATTCAACAGGATGACACATATCTGTAGCTTTTTGATGTGGGCTTGTTGTCACCGTAGGAGAGGGTTTATCCCAAGACAATCTTCTATAAAATCCAACTTTGCCACCCCCAGATTTGTAAGCGCCTCCCATTGCTTCAGGCTTTAATTCATCTGGTAAATGTCTCCAGTTTTGACCTTCTTTCAATAAAACAAGATATTTTAGACGTTGTTTTGAATAAGGGGTGTATTCTGGATGTGGATCGGATAAATTAGACAGAGCATCTCTAAGAGTTCGCCATTTCTGAAGTCCTTTTAAGCCATTTTTATCATGAGTTGGTTTAGGAAAAGTTAAAACTTCACCATTTTTTGACCCAATAAATATTACTCTCGCTCTGGTTTGCGGTACACCATAATCAGCAGCTTGCACTAGCATAGGAGGAGCAACTTCATAACCGATTGCTTTCATTTGGGCTAATACAACCTTAAGGGCTGCACCCTCAATTTCATCTGGTTCTAAAGAAGAGTATCCAACACCTCTTTGATTATGAGGCCTATGCCGAATCGGAGATGAAAGTAATCCTTTGACGTTCTCCATTAAAAAAAAACGAGGTTGAATTTCTTTCACAATGCGAATGAAATCCATAAATAAACTTCCTTGTGGATCTATAACAGAACCACGCTTACCCGCAGTGCTGAATGGCTGACAGGGCGGTCCTCCTGTTACTAGGTCTACTTCACCAGGTAAAAGAGGTCTACCAAGTTTTAAAACACGTCCTCCCTCTTCTAGCAATGTTTGTGCTGAAATCTGCCTAATATCCCTTGGTACAGCACTTTCTCTAAGGTGGGGGCGGTTCAGAATAATAGTTTTTGTTGCATCAGCATCTATTTCAACTACGCTGACAGTATAAAAACCTGCTTCTTCTATACCCAAATCAAGACCGAAAGCTCCTGCAAACAGAGCAATGGATATTAATTGGTTATTAATCACCTTTTCCTCAAATTTTCAAAATCAATTTTACTCACATTTAAACCTAATAGATTTTTATAATTTCCACGAAATCGTCTGCGTGGGTATTTTCACATTGTCGTCTAAGTTTTTTACAAATACTACCTTGCCTCTGCTGCATGGAGTAGGCGAACATAAGTTCCGCCTTGCTGCCATAATTCCTCATGGGTACCACTTTGGACAATTTTACCTTGGTCTAGAACAATAATTTTATGGCAATCACGAATTGTACTCAGGCGGTGGGCTACTACAATACATAAGCAACCACGCTGTCGCAAGTTATGGTTAATAATCAATTCAGTTTCCACATCGAGGGCGCTGGTTGCTTCATCCAGTACTAATATTGTGGGATTTCTCACCAAAGCGCGGGCGATTTCTAAACGTTGGCGTTGCCCACCACTGATATTCATACCGCCTTCAATCAATTCAAAGTCATATTTTGCAGGCATAGAAGCGATCGCATCATGAATGGCTGCATCCTGACAAGCTTGCACCAAATCAGCTTCTGGCACAGTTGAATCCCAAAGAGTGATATTATCTCGCACAGTCCCCGCAAATAAAAAGATATCCTGTTCAACCATTGCCAATGAGTTAGCCAACACAGAACGCTTAATTTGCGATCGCTCTACACCATCAAAACAGATTTCCCCTGCCCAAGGTTGATAAAGACCACAAATTAATTTAGCAATCGTAGATTTCCCTGAACCGCTTCCCCCCACAAGCGCTATACGTTGTCCAGGTTGAACAGTTAAGCTAAAATTCTCAATTAAGGGAGGTTCCACCCGACTGTAGCCAAAAGTGATATTTCGTAACTCAATATGTCCCTGTAATTGCCACATTGGGCATGGGGCATTGGGCATTGGGCATTGGGCATGGGGAATACTTGTAATAAGTTCCCCTCTGCTCCTCTGCTCCTCTGCTCCCTTGCCTCCCTCCACTTCCAAATCAACAGGATTTTGCAGCACATCATCAAGCCGATTTAAATCAGCTTCTAAATCTTGCAGCGTGCTGCCGAAATTTACGAGGCTATTAACTGGCTCTAAGAAGCTCAGTGTTAAACTTTGGTAGGCAACGAGCATCCCAATACTGAGATTGCCCTTCATTACCTGTAAACCACCAACCAGCAAAATAGAAGCTGTGGTTAGGGCTGTCAAAATTGTGGGTAATGTGGTGAGAATTTGAGTTTGTAAGCCTAATTCCTGTTGGGCGTTGAGTGCTTTAGCGTAATAACCCGCAAACCGAGCAAATAAATCTGACTCTAGCCCAGAAGCTTTGATGGTTTCTATCGTTTGGATGCCGCTAATCGTTACTCCACCCACCTTGCCATATTCCTGAGCTAGGCGCATATTTGTATCTACACGAGTTTGCGATAAAAATAAGAGGGCGAGAATGTTGATTAAAGCAAAACCAACTGCGATCGCACTCAATAATTGGTCATACTGAATCATTATCAGCAGGTAAAAAACCATCATTACTGCGTCAATTAATGTGGTTGCCAAAGGCCCTGAGAGTACTTCCGCCACTCGGTCATTCAGTTGCACCCGACTACTGATTTCCCCAGCAAAACGTTGGTCATAAAACCCAATAGGCAATCGCAAAATATGCCAGAGAAATAGTCCTGATGTGCTGACTGACAACTTAACCATCAATCGCCGCAGATAAGTCAGCCGCAGTCTCGCAAGGAATGCCCGCAATATAGTAGTTAACAACATCCCTAACAACAAAGGTCGTAACCAATCTTGCCGGTCTTGGATTAAAATCTCATCGATAAACACTTGAGCAAAGGCTGGAACCGCTAGCCGAGGCAATGTTAACAACAACCCAGCCAGCAGACAAAACAAGATAGTAACTCGTGAGTTTTGTAAACGGGTAGTTAAAGCCGAAATAATGTGATTTTTTTTGCCGCCCTTCTGGAAGTCCGCTCCTGGTTCCATTGTCAGCACAACACCAGTATATGCGCGATCGAACTCTTCCCAACTCACTGTTCTCCGACCACTAGCAGGATCGTTGATGTAAACGCGTTTTTTGCTATATCCTTCTACCACGAGAAAATGGTTAAAATTCCAAAAGGCAATGTAGGGAAGACGGGTAGCTGTCACCTTTTCTAGAGATAGTTTTAAACCTTTAGCATTGAGTCCATAGTTTTTTGCAGCTTTGAGAATATTAAAAGCTTTACTCCCATCCCTTGAGACACCGCATTCTTCACGCAGTTTAGCCAGTGGCACAATCCGGCCGTAATAGCTAAGAATTATTCCCAAAGCAGCCGCACCACATTCGACCGCTTCCATTTGTAAAAGTGTAGAAGTGCGAACACGATTTGGTTTAAATTTTGGGATTGGGAATGGGGGATTGGGCAT

Protein sequences of DBSCAN-SWA_4

>NZ_CP046703|1893167:1946358|1900534_1901137_+|WP_114082604.1|DBSCAN-SWA
MKTYTKQKLTFDQFLEECPEEGLYELVDGEIVEVRATRNHDDIADFILLSFNDEIKHLNLNYVVKNTAVLKTITANGIEQGRKPDVSVIDKDVWRSNRSAYSALEEPIQLAIEVTSTNWEDDYIDKLDEYQRIGITEYWIVDYLAIGYREYLENPKVPTVFVFLLDAEGKYQRTDFRGSERIVSRTFPELALTAEQILTA
>NZ_CP046703|1893167:1946358|1912258_1914571_+|WP_114082591.1|DBSCAN-SWA
MVKRSLQASLIGIEQAKRAFALKGWTQDNLSAEVNLKTRQPIWRFFSGRPVERHTFIEICSVLELNWREIASNPPAEFMELEEYGRPPVLDIDGLVEKVRSQRFDKIQDQCGILQLLDISRPVAIDDIYIDVNILEEIASQQWLEITALQNLDPKQFDRFGLGEADQNQIPGTQAVETYSKLRVLGKPGVGKTTFLQYLAIQCNQGTFAGNLVPIFITLRNFAEESKVTNEFSLLKYIRQEFLTSGVSDSSAIETLLSAGRVLILLDGMDEILNQQSNTVLSEIRRFSEKYHKNQFVAACRTASQKLRLRGFTDVEIAPFTSEQIIAFAQKWFVAFTKTNIQDGQALSVQFVEKLDLDENWQFRQLVVTPLFLHLACWVFHGQEKFPTKRTDFYKQGLDLLLGKWDEARGIERDEVYRGFLLPQKLKLLSQIAAATFEQGQYFFEQRIVEQYIGDYIQNLTKAPMDAEELQIESEAALKAIEAQHGLLAERARGIFSFSYLAFQEYFTARKIVASHNLEAFGEALEGLVSHITDPHWHEIFLLTATMLRSADSLVQLMKQQIDALVGQDPYLQEFLTWASQKSRTIPSQAKEATTRAFYLALSRTPHIASHFALASSLDQGMFLDTALDDLLLECAIDGSQDFAHIHACGDALSNILGIVLDVGLHKSLQQLSDQLPSSRQNQERLRLWGQTNYAAWAEQLKMKVINYRNINHQWQFSTEQQQVLQRYYDANKLLLDCLHSNCEVTAAIRREIEATLLLPQKELEDREWQ
>NZ_CP046703|1893167:1946358|1920071_1920224_-|WP_159402476.1|DBSCAN-SWA
MPLLVFETAFHIPSELCQDMRVGTNADKGGRSAVRKLDCGENVVHFYFEA
>NZ_CP046703|1893167:1946358|1907448_1908474_+|WP_114082596.1|DBSCAN-SWA
MTLLLAGDIGGTKTILRLVETSDSPALHTIYQESYHSADFPDLVPIVQQFLIKANTPIPEKACFAIAGPIVKNTAKLTNLAWYLDTERLEEELGIPHISLINDFAAVGYGISGLQKQDLHPLQVGKPQPETPIGIIGAGTGLGQGFLIKQGNNYQVFPSEGGHADFAPRNEIEFQLLRYLLGKHDIQRVSVERVVSGMGIVAIYQFLRDRKFATESPDIAQIVRTWEQEAGQEEKSVDPGAAIGAAALEKRDRLSEQTLQLFIEAYGAEAGNLALKLLPYGGLYIAGGIAPKILPLIQNSGFLLNFTQKGRMRPLLEEIPVYIILNPQVGLIGAALCAARL
>NZ_CP046703|1893167:1946358|1924140_1924689_-|WP_114082584.1|DBSCAN-SWA
MQKRQKSRFLFSDRWLDRHSIVRNMEAFQDLIVIVLCLGLFAVMLIQLWGIAIALMQPLDYKHVTAKILFVLILVELFRLLMVYLQEHSISVGVAVEVTIVSLLREIVVHGALEISWVNTLAICGLLFVLGGLLVVCAKTPHMDCMSANTKFCPVVYRGGRERQNDLEFQYSRQCDENKPLG
>NZ_CP046703|1893167:1946358|1898317_1899562_+|WP_114082606.1|DBSCAN-SWA
MNNAIAQTTALLSTCALLLTGCGGGGGSVTNTPNSNPNNTTNTAQTTTTSGAIPIGIALAQTSNVALLGQEGFVGARIAEKYFNSKGGINGTPIKLIAQDTSGDEAGAINAFQTLINKDKVVGIVGPTLSQQAFSADPIAERAKVPVIGASNTANGIPEIGDYVARVSAPVSIVAPNSVKAALKQNPQIKKVAVFYAQNDAFNKSETEIFQKAVKEQGLELVTVQKFQTTDTDFQAQATNAINLKPDLVIISGLAADGGNLVRQLRELGYKGIIIGGNGLNTPNVLSVCKALCDGVLIAQAYSPEYPGEINKVFRQAYIEQYKKEPAQFTGQAFAAVQVYVEALKELDKKTKISTLPLDKLRTELNKQILAGKYNTPLGEIAFTPVGDVIQKEFYVAKIKMDKDGNTGKFVFIK
>NZ_CP046703|1893167:1946358|1915550_1916768_-|WP_114082589.1|DBSCAN-SWA
MNFLESVQMAGKTLLSNKLRSALTMLGIVIGNASVIAMIGIGEGGQKYVNKQLESLGPNVLFILPGNRETQRISFEVPKTLVLQDADAIASQVPTVVGVAPELNRRQVVTYSNRNTDVNIIGTTPSFLSVRDFETAKGRFFSEVDMKRSNQVVVLGGDLAEKLFGNSNAIGQQLRIGNTSFQVIGILIAKGSSVGADYDDAALIPITTSANRLVGKNSPYGIALDYLVAAARDSESVDAAEFQIANLLRLRHKINGEDDFTIRSQKDALQTVGQITGALTIMLAAIAGISLFVGGIGIMNIMLVSVTERTQEIGLRKAIGATEQDILLQFIIEAVIVSAAGGLVGTAVGISGILLVGALTPLEASLSPVAITMAVGVSGGIGLFFGVVPARRAAKLDPIVALRSA
>NZ_CP046703|1893167:1946358|1924776_1925700_-|WP_114082583.1|DBSCAN-SWA
MRLSFSKYPIAGLVSLTLLVVSIPSPSLSLSGSVPSKLAQSNGKTAIDWLNQGLQAIQAGKVKDAIAAFKQAAKLDPTLAPAYYNLGLAYRQTGQLQPSADAFYRATQADPKFAPAFANLGGALLEGNNLQLANDYLQRALELDPKLGFAHYNFGLVREQQGDCEKAIASFKKAIEYSKNAPEPPYHIGMCYLQQGKLDQARDAFNQAVKINPKYPEAYYNLGSIWFQQNKLQEALEAFRKSAEANSNYPNAYYGAGLVFMQLQQYGDAVQVLQFARDLYNSQKNPQWAKNAEQLLQQAQNLNYKPR
>NZ_CP046703|1893167:1946358|1942807_1943983_-|WP_114082569.1|DBSCAN-SWA
MINNQLISIALFAGAFGLDLGIEEAGFYTVSVVEIDADATKTIILNRPHLRESAVPRDIRQISAQTLLEEGGRVLKLGRPLLPGEVDLVTGGPPCQPFSTAGKRGSVIDPQGSLFMDFIRIVKEIQPRFFLMENVKGLLSSPIRHRPHNQRGVGYSSLEPDEIEGAALKVVLAQMKAIGYEVAPPMLVQAADYGVPQTRARVIFIGSKNGEVLTFPKPTHDKNGLKGLQKWRTLRDALSNLSDPHPEYTPYSKQRLKYLVLLKEGQNWRHLPDELKPEAMGGAYKSGGGKVGFYRRLSWDKPSPTVTTSPHQKATDMCHPVELRPLSVREYARIQTFPDTWVFYGSLSSRYRQIGNSVPVKLSHAIGQYLSKIIKNEKPESTNVFEQLSLF
>NZ_CP046703|1893167:1946358|1928561_1929458_+|WP_114082581.1|DBSCAN-SWA
MGFIISLLTSLIGILVYLNTGRISGEKSRLAIRTITILISSIAILNSISRLLVIVPPGNIGVVNLFGEVSESTLNPGVHFLNPFNKVLNFSTRIKDLKENIDVTTQEGLSLNLDVSLQYKLDPQKAATVYKTIGTDETQLVISRFRSTVRAITSNYPASAIYSTKRQEIAQKIDQQLTQEIPTLGFIVEEALLRNVKMPDILQVAIQNKLKTEQENQQMKFVLEKERQEAERKRIEAQGIADYQKIISVGLTNQVLQLRAIEATEKLAQSNNSKIVIIGSEKGGAPILIQPETGTSRP
>NZ_CP046703|1893167:1946358|1905858_1906422_+|WP_114082598.1|DBSCAN-SWA
MIKSLTKTFTLEEFLKLPETKPSSEYINGQIIQKPMPQGKHSILQGELVSNINSVTKPQKIALAFPELRCTFGGRSIVPDIAVFAWERILLDERGEVVNVFKTSPDWTIEILSPDQSQTKVTGNILHCLKHGSRFGWLIDPDEHSVLVYPPKQQPELLQEEQEILPVPDLVNGFQLTVGQLFGWLKL
>NZ_CP046703|1893167:1946358|1897764_1898091_+|WP_114082607.1|DBSCAN-SWA
MLKTLLVIAVGFLPSLISLWAIRKTHARSRLRMRQAAMNFSVVQGRQNLRPVDSDRYYLEGVGYLIGDISCKFNARSGYMRCAVNPDGPCNGCRHYEPKGLPGSEKGV
>NZ_CP046703|1893167:1946358|1920403_1921414_+|WP_012411359.1|tRNA|DBSCAN-SWA
MGKQRVLSGVQPTGNYHLGNYLGAIRNWVEGQSEYENYLFVADLHAITVPHDPKQLAADTYTLAALYLACGLDLNHSTIFVQSHVSAHSELTWLLNCITPLNWLQDMIQFKEKAVKQGENVSAGLLDYPVLMAADILLYQADKVPVGEDQKQHLELTRDIAARLNHQFGKPDQPVLKLPDPLIRKEGARVMSLADGTRKMSKSDPSELSRISLLDSPEQIQYKIKRCKTDPIRGLTFDDPARPECNNLLTLYTLLSGKRKEDVAVECQDMGWGQFKPLLTDTIIESLKPIQEKYQAVTADKSYLESVLRDGGEKARAIANQTLSQVKAALGYSLPL
>NZ_CP046703|1893167:1946358|1893167_1894496_-|WP_114081517.1|transposase|DBSCAN-SWA
MGKHQSVSIRQISKNRAEQIGYYRFLENKSVTVGELVRSLSDHCVSHVEGKHILAISDTSEINLQSHVGRLEALGLGVVGNNRDIGFYIHPTLVLDAANGFPLGISTVKLWTRDINHQDKHERNYSQLPIEEKESYKWLRSADETQQCINVGEAKMITHIGDRESDMYEEFVTVANQDNHVLVRARIDRRLVGKTSSFYTYLNQQPSEGTYTVDVPADARTSRTAREALLIVRRAMVKIQRPDKLNGQDYPPSVTLYAVEAVEVNPPPGQAPIHWRLLTTHQVVCLEQALQVIRWYTWRWRIEQLFATLKTAGLNLEATQLESIAAIQRLTVLALSVAVRILQLIQGRDNPNLPATVAFSHEQQHCLSSISPTLEGKTQLQQNPYLPSSLPWATWIIARLGGWSGYKSQKPPGITTLVRGLEQFESTFFGWKLALGKLVCTP
>NZ_CP046703|1893167:1946358|1929574_1929967_+|WP_167756008.1|DBSCAN-SWA
MSGDIVEKLKKASTGLLMMSESDYPFEVVQWEGAAPATQEKILQLTGSQNLPVEVVELDYFLRNCAFEQEWHNELQKKDVKRFQTLMQTLKDNLSDISVYRVGQINIDAYIIGQTQDGDLAGVVTKLVET
>NZ_CP046703|1893167:1946358|1905093_1905825_+|WP_114082599.1|DBSCAN-SWA
MKADSRPNYTILEVQELDVNYGGIQALKKINLIIQKGEVVTLIGANGAGKTTTLRAISKVVNSKSGVILYNGHNITRRQTHEVVQLGIAHCPEGRRVLARQTVFDNLLLGAYIRSNQAEIKADIQRQFELFPRLSQRRNQLAGTLSGGEQQMLAIARAVMSKPQLLLLDEPSLGLAPAIVREIFSIIENLRATGVTILLVEQNANLALQIADRGYVLEAGSITLTGAASELISDERVKKAYLG
>NZ_CP046703|1893167:1946358|1901321_1902284_+|WP_114082603.1|DBSCAN-SWA
MAEFFSTYESPIVYMVLEALLGLSLYLPLMAGQLSLASPGFYALGGYIAAILSTKVFPSSNNLFPIPLLLLEMLIAGLISGILAVIVGIPALRLRGIYLAIATIAFVEVLRVVSLNLDITGGAVGIFGIPQPFQSQIEYLWIAVPFLLVSMVLFYRLERIRTGRAFIAIREDELAASAMGINPTYYKVLAFTLGAILAGMVGVISAHFLNTWNARQGTFDASITYLTIVLIGGSRTFLGSVVGAIVLKVLLEIVLRRIADIAGLPNWLSQFLRDGRLIIYGILIVLGTIFFPQGFVTPDILKKCKNLLIKSISKTSKQTR
>NZ_CP046703|1893167:1946358|1914919_1915390_+|WP_114082590.1|DBSCAN-SWA
MAGLVMNLINGFCLTDGILKGVEVLVVDNDRDSRDLYAFLLKDQSANVITAGSVKEALEILSWFTPNILVCEIRFLGESIYTLLNTLSAMEADNGKHIPIIVTSTSTTGTHDLIPNVEFEKYLLKPFDLDKFVSMIRNQVQEDVSQNFCPDVLVLH
>NZ_CP046703|1893167:1946358|1914691_1914838_-|WP_159402475.1|DBSCAN-SWA
MSQVDLVKRRIHWKRFRTNLSKLRAASVSGEEWLQRKVPKEGFLLEIK
>NZ_CP046703|1893167:1946358|1938657_1941543_-|WP_114082571.1|bacteriocin|DBSCAN-SWA
MSSPQVNPSSKLYSFQANESLLLNNSETVWIVESGTLAVFATRVKNNLLKEQRRYLFHVNAGEALFSAALLPKESKWSFIAIAIEPTQLCQMSMVDLVQGIGTADSQAIELLEGWVNHLSQSLSSQQTVLTTPLNIVQTSGQDFSLSTGEALHLWQQTLVWVKLQQGNVSWMGVEELTLNPTSPAFPLTSAMWLEAENAVIGQVLTTADFPSQEEILSSLVCLHTYFFHYLSLLANKQAEAEFRQFQQREQLNQQVIEGALSELATVLQPQQEALSQEGPPLLVAMGAIGRTLGIEIRPAADNFSSIKDPVAAIAQSSQIRIRRVTLASGWWRQDQGPMLAYTQLEKRPVALLPTDKRDYTIFDPVARTRIPVNEAVAKTLTTSAYVLYRPLPQVALKAIDLLRFGVKGYEKDIASILVVGLLGTILGMVAPQATAILINNAIPDSDRALLWQIGLVMFAVAFGQLAFQIAQSIIILRVESATDSVLQPAIWDRLLRLSPRFFRQYTAGDLVNRVMAVREIHQKLSGATQKTLLSGVFALLNLVLMFIYSWQLALVGVGLAIFAAVVTTVASFRLVKKSREQQELNGAIQGLTVQLINGVAKLRVAMAEERAFAAWAKKYSQQIRLKANWQQIKDGMSVFNEALPLVSSILLFGLAMLLIQPRLTLGIFVAFNYALTIFIKGIIDLSNTVSEIWGIVPIWERAKPIWRSQPEDGSTKVNPGQLSGRIALESVSFRYSEHGNLILNNVSFHAEPGEFVAIIGPSGSGKSTIFRLLLGFETPLTGSVYYDGQDLADLELQAVRRQLGVVLQNGKFGTGSIFDNITAGALVSLEEAWEAAQMAGFADDIKQMPMGMHTIIAEGGTNLSGGQRQRLLIARSLVAKPKIILMDEATSALDNRTQAIVTESLAKLNATRVVIAHRLSTIRHADRIYVLDAGNVVQTGNFSELIAEEGLFARLVVRQS
>NZ_CP046703|1893167:1946358|1908519_1909122_+|WP_114082595.1|DBSCAN-SWA
MTVKSLLPLIAATFICGGSILVEARQPKPPVVVVKPAVPKIVQPQWKVYTAPDGRFTILMPGRPNRNTEFQKTYMGEIALEIFAAQPPKQEVAYIVVYNDFPYSYGKITDPQAVLNNARDMALKTTKSNLISQRNIRSYNNHPGKEIEYINSGGKITKSRMYVAEGRLYQVMAITTKKQQKTLAKTITGYLNSFNLVLKK
>NZ_CP046703|1893167:1946358|1911204_1911492_+|WP_114082593.1|DBSCAN-SWA
MSLIKLNQSLVSLMNLFQSNQSEFAWWVEINTAVPRCTYYFGPFDSEKEAQLYRSGYVEDLYQEEARDIIALVKQCQPDDLTIFHEKAEVQISSF
>NZ_CP046703|1893167:1946358|1911455_1911860_-|WP_114082592.1|DBSCAN-SWA
MSLLSINKIYKIIEMAELIYGTMGYGRTNQPETFIDKLSYYLEDLNITGRCSINILQKYIHEFSEEEKVEVIALMWLGRTALSEQAEDFLNLLKQVVELIPQNYATSYIIEKPLLAKYLRDGLQKLDIWTSAFS
>NZ_CP046703|1893167:1946358|1897031_1897538_+|WP_114082608.1|DBSCAN-SWA
MKKILDTDKKPILLKVSLLQPTPVTTAIVPLQPQQEKIISERERLITQVERINQMAGELEAAILELKAIANTLNSQKRYPLLKKELGKQICQYFAISVPWVKRKPDESFILTTRKVDLFRAEREAALLAQQLRQQTKKRLASQRHRKNKNGAETDTRHLCKKALVNKS
>NZ_CP046703|1893167:1946358|1894945_1895986_+|WP_114082610.1|DBSCAN-SWA
MINQHSQNLLDTQLENAPGEGYIFSWFDWFCLWYPPGWLILFNRHWQHYHTDIDGWNWPEYGLFLIPGGFYLAMLIRWLRLGFRSPRKELGEFDPKYQQAFRKEVLGPIVKYYFRGELKQVENLPQTGPLIVVMNHAGMSFPWDFLTLGYLLSEARGWVVQPVASPALFDHPWVIWWLPPKWSQVLGGVRAELDNFEAAMAQDKIILYAPEGIRGPLKGWKRRYQLEKFDVSFVKLSDRYHIPILPVVCIGSEFLHPWAVNFQKLQRLVKLPFLPVSPLMFALILFPSMGIWAMRTRLHYYIQPLEPAELHNSNKGRTEAYQQAQQLREKLQFKINSETIDRVNIS
>NZ_CP046703|1893167:1946358|1944102_1946358_-|WP_114082568.1|bacteriocin|DBSCAN-SWA
MPNPPFPIPKFKPNRVRTSTLLQMEAVECGAAALGIILSYYGRIVPLAKLREECGVSRDGSKAFNILKAAKNYGLNAKGLKLSLEKVTATRLPYIAFWNFNHFLVVEGYSKKRVYINDPASGRRTVSWEEFDRAYTGVVLTMEPGADFQKGGKKNHIISALTTRLQNSRVTILFCLLAGLLLTLPRLAVPAFAQVFIDEILIQDRQDWLRPLLLGMLLTTILRAFLARLRLTYLRRLMVKLSVSTSGLFLWHILRLPIGFYDQRFAGEISSRVQLNDRVAEVLSGPLATTLIDAVMMVFYLLIMIQYDQLLSAIAVGFALINILALLFLSQTRVDTNMRLAQEYGKVGGVTISGIQTIETIKASGLESDLFARFAGYYAKALNAQQELGLQTQILTTLPTILTALTTASILLVGGLQVMKGNLSIGMLVAYQSLTLSFLEPVNSLVNFGSTLQDLEADLNRLDDVLQNPVDLEVEGGKGAEEQRSRGELITSIPHAQCPMPNAPCPMWQLQGHIELRNITFGYSRVEPPLIENFSLTVQPGQRIALVGGSGSGKSTIAKLICGLYQPWAGEICFDGVERSQIKRSVLANSLAMVEQDIFLFAGTVRDNITLWDSTVPEADLVQACQDAAIHDAIASMPAKYDFELIEGGMNISGGQRQRLEIARALVRNPTILVLDEATSALDVETELIINHNLRQRGCLCIVVAHRLSTIRDCHKIIVLDQGKIVQSGTHEELWQQGGTYVRLLHAAEAR
>NZ_CP046703|1893167:1946358|1935996_1938213_+|WP_114082572.1|DBSCAN-SWA
MHNTEFEQEILFLRQQNAQLQQQLAKSTTEFSAEIAQLEQKLRESKQLLESNCQAELTFKASQAELLALFNAIPDVILMLDAEGRYLKIAPSSAPLLYQPPVELIGKTMHEVLPSAFADSFLNCIQQALETKKTFKIEYSLPIGDQEVWFEASIAPMNEDTVVCVARDISNVYNELRLRKAAEATLSQQEDQYRSIFETVNDGISVVDLDTGKIVAANPAFCQMHGYSQAEFFHLSPTDFIHPDSFQQFAEFINTIKMGGEFHTQAVDIRKDGTYFDIEVTGKLFNYNGKPHALSVVRDISERKLAEQEQRRLLTILEATTDIVGMADVDGNNCYLNKAGQKILEIPASETNKFHISEVTGLSILEKFQNEIIPIVVREGIWSGESIFRCRNGEEFPVSQVIIAHKNEQGEIEFFSTIARDIRDRQQIEARLRQHAEDLAQTLQELQRTQAQMIQAEKMSSLGQLVAGVAHEINNPVNFIHGNLSHLEEHTQDLLRLINSYQIINPPEFQNGNCYSGEASYALAERLNPLLTLCQEIDLEYIQQDLPKILNSMKVGTQRIRQIVLSLRTFSRMDEAEFKAVDIHEGIDSTLMILQHRLKEKPEFPEINVIKNYGSLPLVECYAGQLNQVFMNIFANAIDALEQKTDNEVSPPTITIHSTLIDSHWVKIAIADNGLGMPEGVEKQVFNPFFTTKPVGKGTGMGMSISYQIITEKHGGKLECYSKPGQGTEFVIKIPIRH
>NZ_CP046703|1893167:1946358|1902315_1903086_+|WP_114082602.1|DBSCAN-SWA
MTNNIVLEAKSLTRRFGGLVAVNNVSFTVNQHEIFGLIGPNGAGKTTLFNLITAFIPLSSGELRYQGANISQLRPHQIAGLGIARTFQNIRLFGELSALENVIIARHLDNKSNLLTGVLGLPPARREEKKSRRKALQLLEMVGLSDRADEKAKNFAYGDQRRLEIARALALEPQILLLDEPAAGMNPNEKQQLSEFIRSLREQFNLTIVLIEHHVPLVMGLCDRIAVLDFGQLIALGEPAVVRNDPAVIEAYLGNE
>NZ_CP046703|1893167:1946358|1906716_1907364_+|WP_114082597.1|DBSCAN-SWA
MSQIVWIARHANRLDFVNPDWFLTAERRYDPPLSDDGMVQAQQLARRLKKENIGHIFASPFLRTVQTANAVAELLNLPIKLETGLSEWLNPAWMTEEPERLSAPALAKLFPRIDTSYTSRIAAKYPETHEKVRERSGQTARCLATEFFPEDILLVAHGASVLGGAMGLVGEIAKTEVKASLCSLVKVVREDPEWLLELTGDTSHLTHIEEVIRFA
>NZ_CP046703|1893167:1946358|1903101_1903983_-|WP_114082601.1|transposase|DBSCAN-SWA
MTKPADVSTKKLISLAPNNWVRWVTQIPDIVAGEILNSEFQWISRESDVLIRVSSPQHGEFLLLNELQLRYQSQMPRRMRAYAALAEEKYNLPTYPVLINILKTGNNEIPTSFTSNIAGLRAIQDYRVINLWEIDVNIAFQQPLPSLLPFVPILKGGENESIIREALQILRADEQLNQLETVLAFFATFVLENTLVQEIMRWDMSVLRESPWYQEILREGEARGEARGEERGKASGELRGILSAIEINLELKFSDRGLQLMPEINQIQDLERLKTILRNIVTANTIEELQQIL
>NZ_CP046703|1893167:1946358|1926180_1928229_+|WP_114082582.1|DBSCAN-SWA
MNEKVKSGSRNVAIVGPYLSGKTTLLESLLFVTGAISRKGSIKDSNTVGDSAAESRDRHMSVEVSAASTEYNGICFTFIDCPGSVEFAQETYNALIGVDAAIVVCEPIRERVLTLAPLFKFLDDWEIPHLVFVNKMDRANIHVLETLHALKAVSSRPLVAHQYPIMNGEQLTGFIDMVSEQAYKYHPGAPADPIPFPESLKEEEHEARAEMLEALANFDDHLLEELLEDIEPPQEEILKDLKMELGADLVVPVFFGVAEQDYGVRPLLEALLREAPEPEATAERRLKNLKGDTPLAQVLKTYYTPQGGKLSLVRVWRGKLTDGIVLNGIRTGGIYRLMGQQQQFVNQANAGEIVALSRLEGIKTGDTISIEQQSAIELPKATQLEPVYALAITPEKRNDEVKLSSAITKLLEEDCSLAWEQHGDTHEVILWGQGEIHLQVTLDRLRRKYNLPMTTHLPQVPYKETIRKTVASVHGRYKHQSGGHGQFGDVFLDIKPLPRGTGFNFNETIVGGVVPKQYIPGVEMGVREFLTHGPLGFPIVDLAVTLTNGSYHNVDSSEQAFKQAARLAMQTGIPQAEPTLLEPILRVEVTTPSEFTSKVLQLLSGRRGQILGYEGRNDWQGWDNVSAYLPQAEMQNFIVELRSLTLGVGSFHWEYDHLQEVPEKLAERVIHSNGNSGNGNGK
>NZ_CP046703|1893167:1946358|1933880_1935107_-|WP_114082574.1|DBSCAN-SWA
MQTLPIVDTSNTASSQPVFDTTIKRRKTRPVKVGNVTIGGGYPVVVQSMINEDTLDIDGSVAGIRRLHEIGCEIVRVTVPSMAHAKALAEIKQKLIKTYQDVPIVADVHHNGLKIALEVSKHIEKVRINPGLYVFEKPNVNRTEYTQSEFDEIGDKIRETLEPLVVSLRDQGKSMRIGVNHGSLAERMLFTYGDTPEGMVESAIEFIRICESLDFRNLVISMKASRVPVMLAAYRLIAKRMDELGMDYPLHLGVTEAGDGEYGRIKSTAGIATLLADGIGDTIRVSLTEAPEKEIPVCYSILQALGLRKTMVEYVACPSCGRTLFNLEEVLHKVREATKHLTGLDIAVMGCIVNGPGEMADADYGYVGKTPGYISLYRGREEIKKVPEDKGVEELINLIKADERWVEP
>NZ_CP046703|1893167:1946358|1931979_1932174_+|WP_114082577.1|transposase|DBSCAN-SWA
MNESQTWYIVKHSAGNCEIVPSDKICDDNLEIKETIEQWGPFSSQGEAIARRVGLIRAGKCQPV
>NZ_CP046703|1893167:1946358|1935719_1936004_+|WP_114082573.1|DBSCAN-SWA
MVSIPGYHVTEEISNGSRTLVYREYRETDFSLKDDFGLDRRRYVGYLQEFLAIARKIIVEKNSGSIQCDSSPGQGTEFEILIPVQQSAGETSNA
>NZ_CP046703|1893167:1946358|1922521_1923334_+|WP_114082586.1|transposase|DBSCAN-SWA
MQTDKIFYSLFQSFPSIFFAIIGDNTVNVNAYQFVSVELKETAFRIDGVFMPTTETTNQPLYFVEVQFQLDPTFYRRFFAEIFLYLRQNESVNFWRAVVIYPQRSLDPSDQLPYQSLLNSSQVQRIYLDELDTAENSLQVAIVKLIIEREETAVDKGRELILQARQQLADEATRKQIVELIETILLYKFTRLSREELAEMLGIDDEFKKTRMYQSIKQDGLEEGRQEGKQEAKLEAIPRLLALGLSVEQVAVALDLTVAQVQQVAQNQSG
>NZ_CP046703|1893167:1946358|1935275_1935446_-|WP_159402477.1|DBSCAN-SWA
MPKALSLQRSKSVILIKYQTYWYIATQLSQQRKYTRQIITAIVSSTYNSVKERSRR
>NZ_CP046703|1893167:1946358|1932252_1933536_-|WP_114082576.1|DBSCAN-SWA
MVITKSRLVLGATAVTLSTIAVTSLGIHSRGQALFKASPKEIVDEVWQIVQRQYVDGTFNQVDWQAVRKEYLSKSYSNPQDAYKSIREMLKKLEDPYTRFMDPAEFKNMQVDTSGELIGIGITISQDEKTKQLVVIAPIEDTPAFKAGVLAKDVILKIDNKSTKGMDTNQAVSLIRGEAGTQVSLTIQRDGQVKQLDIKRARIEIHPVKYSQKQTPAGNLGYIRLNQFSANAGKEMQTAIKDLESKKVAGYILDLRGNPGGLLFSSVDIARMWINKGKIVSTVERQGEAEKEEANGRALTDKPLVVLVDKGSASASEILSGALKDNKRATLVGTQTFGKGLVQSVRPLEDGSGLAVTIAHYYTPNGTDINHKGINPDVKVELTKEQMQELWLHERDKLATLQDPQFAKAVEVIGKKIAAKGTATAEK
>NZ_CP046703|1893167:1946358|1923431_1923677_-|WP_114082585.1|DBSCAN-SWA
MATNTGNGQSQTAISDLEYDFVTVLHNKAEAVKAYDAYIKDAEQVGSQPCVELFQKLRQSDIEHAQEIRQHLQQVLQHGKM
>NZ_CP046703|1893167:1946358|1941812_1942739_-|WP_114082570.1|DBSCAN-SWA
MLAYALKNEVGFTLNKARSLASYFADIKDFLEFQEENIKNLKSISGKSVLKLTDEEITNLSIYRESGSLSAELTVAENYLAIISRVFTQKQLNMVRNLSLKNLNPNPFLIRALNLDTPDAVVRLNVYMAATRSIVTSMGFFIEDLLLTSSDTVEKAPNKSGWDLVKTTSDGEKFWLQIKSGPNNMDKDQVVYWAEKIQEKVKEGDKAYIGFTYGKRTSKTVTIGLLKQILPDWEMQTLIGKELWNFLSEDSDYSSKLFEVLRKSAHQILHQNSLSEEIDSCANRVTDEFIQDFGDGHQGVSNYINSIF
>NZ_CP046703|1893167:1946358|1931223_1931721_-|WP_114082578.1|DBSCAN-SWA
MRLPIIISAGLLLSFGLNLPVMSKSPIEIAQSSTKNNNLDVRRLKFNRYLWNQQNISNYRYTFSNGCFCIPDARGPVVIEVRNGQTTSITSVATGQAVNPEFFQNYKTIPKLFNVIQDAINRQAYSLNVSYSPKFGYPTKIEIDYNSQIADEEIYLTIENFQEIK
>NZ_CP046703|1893167:1946358|1896288_1896750_-|WP_114082609.1|DBSCAN-SWA
MRLRIYQISDTEEIMKLFYDTIHEVNIHDYTQEQVDAWAPANMDIDLWIKGLSSKFTYVAEENSKIIGFGELEANGHIDRFYCHKDFQRKGIGKKILEQLESKAKALGIERLFTEASITAKPFFESQNFIVVKQQEVERRGQKLTNFIMEKSI
>NZ_CP046703|1893167:1946358|1916778_1918245_-|WP_114082588.1|DBSCAN-SWA
MATHIEIPVIGKVKYPFRWLMGLITGGVLVVGTITTYTLMNQGKKEDIAQLTVPVAAKNVTLRITASGKVVPIQSVNISPKNPGVLSQLYVQQGDRIQQGQILARMDSAGIEAQRSQYRANLAQSQAQLAEALAGSRPQEIAQAKARLAQAQAQLAQARAGNRPQEIAQSQSQVDAAQAKVNYTSEQVKRYQYLYKEGAEKKQLLDQAISEDKSARASLEEAKKRLSLVQSGTRTEEIDQRQAAVNEARAALVLLEDGTRSEEIVQRQAAVASAEAQLKGVQVQLEDTIIRAPLSGIVTQKYAEPGAFVTPTTSASTSASATSSSIVAVARGLEILAQVPEADIGRIKPGQQVEIVADAYPDQVFKGHVRLIAPEAVVEQGVTSFQVRVALDTGTDKLRSGLNVDLTFLGDRVNNALVLPTVSIVTEKGQTGVLVPDAKNKPQFREITVGAQIQDQTQILGGVKEGDRVFVNPPKDYKIEKAKEKSNS
>NZ_CP046703|1893167:1946358|1919149_1920055_-|WP_114082611.1|DBSCAN-SWA
MKQYSHLTIISYILGPTLIVVSHLGSLLIIVTGLSWGAVLWAVLLYVIRMLATTGIYHRLLTHNSYQAPSSVLCVGSIVAASAGQMGPSWWKAHHMEHHQSSDHEKDPHSPYMPFKGIKGFWWSQAGWLFSPQFFPSKLPTDVESNVVLKIVDRLHFIPTFALGAFSYYIGGVEYLGAFFLSTTVLFHCVATVNSLSHILGEQPFKTNDYSRNHWLVAFLTLGEGWHNLHHAFQGSARHGITVREGRVAYLPDPTFWFIKILEFLKLASKVRVPSEPELIARARNRNFQNPVFKAKAKTSV
>NZ_CP046703|1893167:1946358|1921472_1922393_+|WP_114082587.1|DBSCAN-SWA
MYHTHSHTAFRRAVQAGEFLVTAEVAPPKGGNPAHMIQMAATLKGRVHAVNVTDGSRAVLRMSSLLASVILSQNGIEPICQVACRDRNRIALQADLMGAHALGIRNILALTGDPVKAGDHPDAKAVFDLEAVRLLQLIRKMNQGVDYNEKPLTDGALDLFVGAAVDPQCKSWSGLQSRFERKIEAGAQFFQSQLITDFERLEKFMDTIASGYKKPILAGIFLLKSAKNAQFINRCVPGVNIPQHIIDRLAKAKEPFEEGIKIAAEQVQIARQLCQGVHLMAVKREDAIAPILDLAGISPVNQLVSK
>NZ_CP046703|1893167:1946358|1930047_1930887_-|WP_114082579.1|DBSCAN-SWA
MKKIKIFKFLLPFVTVVLFIIGLAQIVPAQSSVSVHLTLGNPSNAGTSSQNNYLLVKPQYVIGYNCGIGRPNWVSWQLNNSWLGSTPRQDTFRADTTLPSGCYQVQSTDFSGSGFDRGHMTPSADRTSSVTNNSATFLMSNMIAQAPDNNQGIWANLEDYARTLVGQGKELYIISGGYGMGGTGSNGTFYTIANGRVQVPNRTWKILVVLNTPGSGLAGVTTSTRVIAVNIPNAQGVRTANWRNYRVSVDSLESLTGYNFLSQVSTSIQSVIEARVDNL
>NZ_CP046703|1893167:1946358|1904076_1904916_-|WP_114082600.1|DBSCAN-SWA
MAKAADIGSKRLINLAPDAWVQWVTQRSEVVAKEILGSEFHWISRETDVLVKAYSATDGDFLVLNELQLRYTAQMPLRMRAYAALAQERYRLPTYPVLINILPPPSTLTIVNSYEQEFLGLRAIQDYRVINLWEIDAEIVFQQPLPSLLPFVPILRGGGEVSVVQRALQALRTDKQLNELESLLAFFASFVLDTPLVQQIMRWDMAVLRESPWYHEIEQRGIQEGARRQLIRVLEQRFGEISHEVEARLEGESVEQLEILMDSAIAVNSLEDFIKILSA
>NZ_CP046703|1893167:1946358|1899569_1900520_+|WP_114082605.1|DBSCAN-SWA
MDITLFLQQFLNGLSIGSIYAIFALGYTLVYSILGIINLAHGAIFTLGAYFTYALMGGNFGFNGLLANAALPIKLPFAIALILGSTLAGLIGVVMERVAFQPLRRQGSDPLLTVVSSLGVAVVIVNLIQYLVGAESYTYPADTYGNLPPAINFGSPDNPIPIRSVQIIIFVVSVAIVAIITYFINRTKYGKAMQAIAEDPTTASLLGINSDRFIILTFFISSFLAGLAGTLVASSVSIAGPYFGIAFGLRGLAVIVLGGLGSIPGAVLGGLLIGLVEAFVPAEYSGYKEAVAYGILFIMLLVRPQGLLGRRFIQKV

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_114081517.1|1893167_1894496_-|transposase	IS4 family transposase	Q9JMP3	Wolbachia_phage	7.6e-38	30.5
WP_114082610.1|1894945_1895986_+	acyltransferase family protein	NA	NA	NA	NA
WP_114082609.1|1896288_1896750_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_114082608.1|1897031_1897538_+	hypothetical protein	NA	NA	NA	NA
WP_114082607.1|1897764_1898091_+	hypothetical protein	NA	NA	NA	NA
WP_114082606.1|1898317_1899562_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_114082605.1|1899569_1900520_+	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_114082604.1|1900534_1901137_+	Uma2 family endonuclease	NA	NA	NA	NA
WP_114082603.1|1901321_1902284_+	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_114082602.1|1902315_1903086_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	3.5e-19	28.2
WP_114082601.1|1903101_1903983_-|transposase	transposase	NA	NA	NA	NA
WP_114082600.1|1904076_1904916_-	DUF4351 domain-containing protein	NA	NA	NA	NA
WP_114082599.1|1905093_1905825_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.0e-15	29.5
WP_114082598.1|1905858_1906422_+	Uma2 family endonuclease	NA	NA	NA	NA
WP_114082597.1|1906716_1907364_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_114082596.1|1907448_1908474_+	glucokinase	NA	NA	NA	NA
WP_114082595.1|1908519_1909122_+	hypothetical protein	NA	NA	NA	NA
WP_114082593.1|1911204_1911492_+	DUF1816 domain-containing protein	NA	NA	NA	NA
WP_114082592.1|1911455_1911860_-	DUF3775 domain-containing protein	NA	NA	NA	NA
WP_114082591.1|1912258_1914571_+	NACHT domain-containing NTPase	NA	NA	NA	NA
WP_159402475.1|1914691_1914838_-	hypothetical protein	NA	NA	NA	NA
WP_114082590.1|1914919_1915390_+	response regulator	NA	NA	NA	NA
WP_114082589.1|1915550_1916768_-	FtsX-like permease family protein	NA	NA	NA	NA
WP_114082588.1|1916778_1918245_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_114082611.1|1919149_1920055_-	acyl-CoA desaturase	NA	NA	NA	NA
WP_159402476.1|1920071_1920224_-	hypothetical protein	NA	NA	NA	NA
WP_012411359.1|1920403_1921414_+|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_114082587.1|1921472_1922393_+	methylenetetrahydrofolate reductase	NA	NA	NA	NA
WP_114082586.1|1922521_1923334_+|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_114082585.1|1923431_1923677_-	hypothetical protein	NA	NA	NA	NA
WP_114082584.1|1924140_1924689_-	hypothetical protein	NA	NA	NA	NA
WP_114082583.1|1924776_1925700_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_114082582.1|1926180_1928229_+	elongation factor G	E4ZFJ7	Streptococcus_phage	2.6e-37	24.2
WP_114082581.1|1928561_1929458_+	prohibitin family protein	A0A172JI70	Bacillus_phage	2.4e-19	29.8
WP_167756008.1|1929574_1929967_+	nuclease	NA	NA	NA	NA
WP_114082579.1|1930047_1930887_-	DNA/RNA non-specific endonuclease	NA	NA	NA	NA
WP_114082578.1|1931223_1931721_-	hypothetical protein	NA	NA	NA	NA
WP_114082577.1|1931979_1932174_+|transposase	transposase family protein	NA	NA	NA	NA
WP_114082576.1|1932252_1933536_-	S41 family peptidase	A0A0R6PIZ1	Moraxella_phage	6.9e-28	28.3
WP_114082574.1|1933880_1935107_-	(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase	NA	NA	NA	NA
WP_159402477.1|1935275_1935446_-	hypothetical protein	NA	NA	NA	NA
WP_114082573.1|1935719_1936004_+	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_114082572.1|1935996_1938213_+	PAS domain S-box protein	NA	NA	NA	NA
WP_114082571.1|1938657_1941543_-|bacteriocin	NHLP bacteriocin export ABC transporter permease/ATPase subunit	W8CYL7	Bacillus_phage	8.2e-37	27.3
WP_114082570.1|1941812_1942739_-	hypothetical protein	NA	NA	NA	NA
WP_114082569.1|1942807_1943983_-	DNA cytosine methyltransferase	F2Y148	Organic_Lake_phycodnavirus	1.5e-50	34.7
WP_114082568.1|1944102_1946358_-|bacteriocin	NHLP family bacteriocin export ABC transporter peptidase/permease/ATPase subunit	W8CYL7	Bacillus_phage	2.0e-30	25.5

Sequences of DBSCAN-SWA_5

Nucleotide sequences of DBSCAN-SWA_5

>NZ_CP046703|3668351:3726015|DBSCAN-SWA
AATACTTACAACTGCTGAAAATTCAGATTGGACAGATGCTCAAATTGCTCAAAATATCGGCTGTTCACAAGCCCTTGTTCGGAAATGGCGCAAACGTTGGTGTCAAACTCGTAGTCTAGAAGAAGCACCCCGTCCAGGTCGTCCTCGGATATTTGAAGCAATTATACGAGCAAAAGTTACTGCGTTCGCGCTTCGCGTTGCCGCAGGCATCGCTTGCAGCAACCCAACGGATTTTGATCTTCCCTTGGCGAGGTGGAGTTGTAGCGATATTGCAGCACATCTAGTCACGCTAGGCATTGTAGTATCCATAGCGACTTCAACAGTCTGGCGATGGCTAAAATCTGAGCGGATAAAACCTTGGCGGTTTCATACTTGGATGCATCGGATTGATGATAATTTTGTTGCAAAAGCAACCCCTGTACTTAAACTGTATGCTCAGGCAAAATTTTTGATTAAAGCTGGATTCTGGGTGGTATGTGTGGATGAAAAAACTTCCATCCAAGCACGATCCGGCTTACATCCAAATATTGGGGCAGGTGTCAAACAACCAGTTCACTTTGCAGCCAGATATGCCCGAAAAGGAGCAACACATCTTTTTGCGGCTTTGAGCGTTGCTGATGGTCTGATTTATGGTTGTTGTCGCCCAACAAAAACATTCCTTGATTTTCAAGGATTTCTTTTAGAAGTATTGATACCAGAAGCCATTCGTCGGGGTATGCGCCATATTTATTTAATCCTTGACAACGGCTCTACCCATGCCCCAAAACAATTACAGGCTTGGTTGAATCAGAAGCAAAAAGAAGACGGTTGGAATTTTACGGTGGAAGTGGTCTGGCTACCAAAATATGCTTCATGGTTAGATCAAATTGAAATTTGGTTCAGCATTTTACAACGTAAATTACTGACTCCAAATGATTTTCCTGACCTCAAGACCTTACAGCAACGTATAACTGATTTCATCGTCCGTCACAATGATTCAGCCCAACCAATCAAATGGTCATATACAGTAGCCCAGATGATGGAGAAATTCGCTACGAATTAATGCAAAGCTGTACTTAGTTTAAGACGAGGAGCAGAAAACTTGGGTTTTAATGCCCGTCCAGTCAGAGCAACTCCCGAATTAATAGAAAGCTTGGATAGAATTTCTCTGCCTGCCATCATTCACTGGAAAGGATATCACTGGGTTGTATTGTACGCACAAAAAGATCGGAAATATGTTATTGCCGACCCAGCAGTAGGTATTCGCAAGCTCAACCATCAAGAGTTATTAGAGGGATGGGCGAATGGTGTCATGCTGTTATTAACTCCAGATGAAACTCGTTTTTATCAACAGGAGTCGGATAAAATAGACGGCTTTGGACGTTTCCTCAAAAGAGTTTTACCCTATAGCAAAATCCTTGCAGAAGCGATCGCAATCAATATTGTAGTTGGACTTCTTTCTCTGGCTTATCCTTTAATGATGCAGCTCCTTACAGATGATGTTTTGGTGAGGGGAGATATACAGCTATTAACTACCGTAGCCATTGCGGTTATTACCTTAAATATTTTTCAAGCTGCTATTGGTATTGTTCAATCTCACTTGGTAGGACAATATGCTCAAAGGCTAGAGTTAGGATTAATTTTAGATTACGGGTATAAACTCCTCCGCTTACCCTTATCTTACTTTGAAGCCCGTCGCAGTGGGGAAGTTGTTAGCCGCATTGATGATATAGAAAGAGTTCATAATCTAGTTTCTCAAATTGTTTTGGGTTTACCCAGTCAATTTTTTATCGCTGTCATTTCTGGTTCTTCCGGTGCTTTTATGGTGGTTACTAAATTTTAGTAAATTTTATTAACTACATTTTAATGATATTTATCCTTAAAACATAGACTGTATAAGCATTGTAGCAGTTTCACGTATACTGAAATAATCCAAATAGCATGATTTATACTATAACACAGTAAAAATTAAGGCTTTCACGCAGTGTGCCGTAGGTATCGCTATGAAATTTACTGTAGAGCAAATCCTGAATCTGCCCGATATGAAAGTATTAGATTTTCAAGAAATTGAAGGGGAAGAAATAATTATAACGATAGAAAAAAGCGTTAACTATTCGACTTGCCCATCTTGTGGGCAAAATACTCAGAGTATACATCAAAATCATTGGCGGATGATTCATGATTTATCTTGGAGTAAAAAGCCAGTACTCTTAAAAATAAATCGTCGCCAGTTCAAATGTCATAAATGTAAAAAAGTCTTTAGTGAGAAATTGGATTTTGTAGATAAAAGTAAAGGATATACAAAAAGATTAGCAACAGACATAGTACAACAAGTATTAAATAGTAATATTCATAGTGTTGCCGAAAGGAATGGATTGAGTGATGAAGAAGTAGAATCAATGTTAAAAAAGCAAGCTTCACAAATATTAAATATTAATCTAAGCCAGGTAAAAAAGTTAGGTATAGATGAAATAGCTTTAGTTAAAGGTCAAGGAAACTACTTAGCAGTATTAGTGGATTTAGATACTCATAAGCCAATTGAAATAGTGCAATCACGACGAATAGAAGATATCCGTGAAGTAATTGCTGGCTGGGGATTTGAAGTACTTAATCATGCTTGTTGAAGTGAGTATTGATCTCTGGTCGCCTTATAAAAGCTTAGTAGAAGATTTAATGCCAAATGCTAACATAACTGCTGACAGGTTTCATGTGATGAAACAAGTAAATGATGAATTAGATCGGATGCGTAAAACTGAGAAGAAAGCAGCAATGTCGTTAGAAGATAAATCCGAAAAATCTCGCCAACTAGAGGCATTAACTAAAAGCAAATATAGTTTAATTAAAAATGAAGATTCTTTAAACGAAAAGCAAAAATCAAAATTAAACTCCGTGTTATAGGTGTCGCCGACTCTGGCTAAAATGCACGCACTTAAAGAACAATTCCGCCAGATATTTGAAACCACTAAATCTTGGGGAGATAGCATAACACAATTATTAGATTGGATGTATGATGCACGTTCATACTTTCCGAAAAGTCTAGGGACAATGGTGAGATGGTTTGGGGAAATAGTCGGTTATTTTGATGGCAGAACTACCAGTGGTACTGTAGAAGGAATTAATAATAAACTCAAGTTAATTAAAAGACTTGGGTATGGCTTTCGGAATTTTAGCAATTTTCGATTACGCAGTTTATTAAACTGGCACTTTTCTATTAATTCTCCATAAAAGTAACGGATGAACCGTTTTTAATAAAACAACAAGAACAACATCCAAGAAGATAATTGAGATTTGCAAAAAGCGTCTGAGCAAATATGATACCGATCAACAGGAGTAATGTGATGGAGCAAGCAAAGAGAGAACGTTTGGAATCTAAAGGCTGGAAAATTGGCACAGTTTCAGCTTTTTTGGAGTTAATACCGTTTCAAGGAAACAAAACAGTTCCCAACTTTTCACGCCCCAAGCGATCGCTCACCTTACCCCGACAAACAACCTGAACCCCATTAATATAAACCCTTTGTACAATCTCATCCGAACCACGCTTAACCATCCGAGGTTCACCATCTAAAACCGGATCTGATATCTGCACTTGCGGGCTAATTGGCTGATTTAAAGCATTGGGATCGAGTAAAACTATATCCGCTTTCGCACCAACTTTGAGAACTCCCGTATTAAGACGAAACCAACCAGCAGGTTCTCCAGTAACGCGGCAAATTGCAGCTTCTGGTGAAAGAAACTTCGTTGTAACTGCTTGTTTGAGCAAAGACAAAGCTCCATCATAGTAGCCCAGGTTACGGACGTGAGCGCCAGCATCGGTAAAACCAGGCAAAATATGGGGATGCTGCATCATCGCTAAACGGGGTTTTAGGCGATCATTCGCTCCTGTCGCCACCCAGCGTAAATCTGTATCGTATTTTTGTAATGCGTGGATAAACAAATCCACTGGTTCTTGTTGCTTTTGACGAGCAATTTGGGCAAAACTTAACCCTTGCCAACTTGCTTCGGGACAGTGAATAACTTCCATCAAATCTAACTGACGATGGAATGATTTACGCCGTTTACTGAGCCATTCTTGGCGAAACTGACGACGGAAAATTTCCGATGCCCATAGTTGTTGTCTTTCTTCTCGTGACTGACAGCCATTAAGTTGTGCGCCTGTGGAGAATTCTTCAAATAAGGGAGTCACAGACCCATCAGAGTAAATGGTGAAGGGTTCGGTTAGGGTTTGAAAGCGCACATTCCCATTTAGAAGCCGATTCCAAATAAATAGTAGCGGGGAAAATATTCGCCATAGTTTGCGATCGTGTACGGCATCTAAGGCTGAGAGGACAGTTAGCCGCAGTGGTTTTTGTCCAATTCCTGAACCCATCCGCAGAATATCCACAAAGGAAGCAAGCCGTTGTAAATTGGGTGTGACTTGAAAAACGCGATCGCTATGCCGACATAAATCCGCTAACATTGCATATTCATTAAATTTGGCGTGTTGAGAAGGAATTGTACAGCCTTGCCATTCTCCACTCATCCGATGCCAGGGAAACATATCAATAGAAATGCCAATAAAGCCAGCATCTATTGCATCTCTGGCTATGCGCTGCATAAGTTTTAGTTCAAATTTTGTCGGCTGAACCGTTAAACTGCGTTCTAATCCCATCACATAAGCGCGTAAGGCACTGTGTCCAAACATTGGGGCAACATTGGGGCCAAGAGGTAACTGTTGCAAATGCTGTAAATATTCTGCTGGTGTCTGCCAGGAAACCGACTTTTTCAACCATTTTGCAATCAGCCGATGGGAAAGTGTCTCTACCCTCTGAAAAATATCAGCCAAGATTTGGGGTTCTGCGATCGCAACGGACAAGCTACAGTTACCAATAACCACGCTGGTAACACCATGACGCACTGATTCGCTCAATCCTGGTGCAATTTCTAACTCTAAATCGTAATGAGTATGAATATCTATAAATCCAGGTGTCACCCATAACCCAGAAGCATCAACCACCTCACGCGCTGGGGTAGTTAAGGAGGGTGCGAGGGTGACAATGCGGCCGTTTTGAATGCCGATATCTCCGCGAACTGGTGGAGAACCTAAGCCATCGAAAATTAACCCGTTTTGAATCAGCAAATCCAACATGATTCTTTTTTGCTCTTGTTTGCTACTGTCCACTTAAACGTCGAAGCTGATCTCGAAAATAGCAGAAACTTGGTGATTGATTATTGTCAATGTCCATAAGGGGAGATATCTTTTCAGCCCAAGTTGCTTTCTCTTTACCAATTGCCTGATAAGCAAATTTAGATAACTTTTGGCAACCACCAGAATATACTGCGTCAGCTAACTTCTCCCATGTGCCACAAATCTCATCGTTGGTGTATGAATTTAGAACTGCTTGTTTTGCACTCGGATAAGCTGCCTTTACTGCTGCTAAATCACCTAAGTACCATGCTTCTCCTTCCTCAATAGCAATACAAAATTGTGTCTTTGGCTTAGGATTACAATAATTTACGAGTTCAAGTAGTTCTTTGCGAAAAGCACTCAGGCATCGGTCATCAAGATCGCAAATGATTATGAGGACAGCAGGGAAATAAGATAAGGGATTTGCAAGAAAATAAGATACCAATTAAACGGGGAAAATTGTGATATGCCATTTAGGTAGAGTTTCGGAAGGTTGCCAGAAGGTTTGGTAGTGTTCTAACTCTTGTGAGAGAACCTTGATTCCTTTTTCATAGGTTGCTTCAACACGGTGAACAATGGGTGCAATCCCTTTCCAAGTCATATTGGAAGCCCACTTGATGGCAACTTCAATCGAATCCAGAATTGCGCCATTCCAATAGTTCTCTAGGGCTGCCCAACACCTCTCTATGGGATTGTACTTGCTATGGTACGGAGGATAGTAAATCAGTCGGATTCTTAAATTAATTGCTTGAGACAGTTCAACCATACGTTTGATAAACTGTGTGCGGTTACTGCGAGTTGCTGCACCACCATCAAGGTCAATCACCCATTCATCATAATCTTGGTAATCGTGTTGATTCTCATACCACCAAGCAGTTAAACAATCGACAATAAAATCACTGGTTTCAGCCGACTGACCTAAGTAAATCGTAAGCTTTTCACTGTGTGTGTTGAGAATGCCAAAAGGAACTAAGACTGCCTCCCACTGTGTATCGTGGTCATCCGCAGCTTTTGCTTCCAGTGTCCGAGCTTTACCACCTCTGGAAAGATTGCCAATCTTCACCTTGGCTTTAGTATCGATAGAGACTCGCAACGATTTGGGATTCTCATCCGATGCCTGATTTTCCTGAAACACATTGTCAAAAATGGCATCTGTTTGCGGAATCTTTTTCAAGGGCTTTGTTTTTTGTGTTTTTTTAGGCGATACCCCAAGCTATTAAGAATCTTCCCCAGAGTTTGACGAGACGGCAATTGACTGTGGTCATAACCTATTTCACTGATTAATGCTTCTCGTACCGCTCTGGCACTGATACGAGCATATAGAAAGGTCGATTGAAATTTTGGATCTGCTTGGGCTTGAGCATCTACCAAAGAACAAATATCTGCTTCTAAATTGGGCAGAATCTCAACACTATTATGTCGTCCCCTTGCATGATAGTTATCCACACAGACTATCCCTGTCCGCCGTTCATGCAAGCCAAGTTGTACACAGGAGCGATTCCATCCTAAAACTGTTTCTGCAATGCGTGCTGAACTATCGAAGTAATCTTCAGTAACTTTTGCCATGAAGTCTCTTTTACAGCTGCCAGTTAGTTTCTTGGCTGCATCTTTGAAGGTAGATTTTATGGTGTCGGTAAGCATGAACCCTGTGATTCCAATTCTAGAAATTCAGAGCAAACGCGGGCAGATCCGCGCCTCCTATTCTTCTAGAATGACTGGTATTTTATTTTCTTGCAAGCCCCTAATGTTTTACCGTACCCTTGAATAAGTCGTGGTAACTGGTCGAGCAGAATTCGTTTTTTGGGATCAGAAGTAGATGTTAGATTTTTAGGAATACGCCCTATTCCTTTGTAATGATGGATATTAAATGTATGTTGTTCGGTGTTAATAATTTTTGGGACAAGAATCTCAAGAGCAATTTTACCGGAAATATCCTCAACGAGTATCTCAAAGTGCATATACTCAACTTGCATCCAAATAGTCACTGTACCAAAGTCCGCCAAGAGGTAAACCTTCAGAAACAAGGTTATTGATCAGAGGATCTTCACTAGCTCGCTTAATTTTCGCAAATCCATCCTCGCCCTTTTCCAAGACCCAAACCTCGTCAGGTTTAAGGGCATCTACAAAATATGGCTGATGTGTTGTCACAAATATTTGTGATCCACCTTTCTGACCTGTAGCGTGTTCTCGAAATTCTCGCGCTAGGGTTTCTAAAAGTTTATGGTAAAGTCCATTTTCTGGTTCTTCAATACACAAAAATGGTGGTGGTGAGGGATCTTCTAACAAGAGGAGATAAGCAAATACCTTAAGTGTTCCATCTGACATATTTTGGGCATAAAATGGGTCTTGAAAACCCTTGTCGTTGAAACGCAGTAGTAGTCTTCCGTCTGGACTTCTTTCGGTGCTAATCTTGTTGACACCTGGAATTTTGCTAGATATTTTTTCAAGTATGGATTGAAACTTTTTAGGATGTTCTCTCTCCATAAACTGAACTACATTGCCCAGATTATCGCCATGAATATTCAGATGCTTTTGTGGCCCAGCCAGAGGCAAGCTTCGTGCAGCATCTGGAGTAAAATAGCTTAAATACCATCCTTCAATAAATCTACGAAATACAGAAATTCTTGGGTGTTGTTTGAGTGAGCCCAAAGTTGCAATTCCCAGTTTCCGCTTATCGTCAAGTTCAACTACCTCAGTTTCCTTACTTTCCTCTTTTCCTTCACCTCTCTGTATTTTTTCTATTAATTTTGACAAATCAAAATCACCTTTTTCTTCCTCAACTTGTTTGCCTTCTTGTTCACCTTTCCATGCAATTCCTCTACCTTCATTGAGAATTAGAAAAGAAAAAGGTTGTCCCTTGCTTTGTCCTTTTCTTCGTTGTCTGAGTCTTTCCCTCTTTACATAAGGTCTTCCAGAGGAGTCAATATCTATTGCCAACTCATAGGTAATTGGCCGGGCATTATGATCCTCTTTATAATAAATATCAAACTCAATACTTCCCTCTTGTCCTTGGGAACGAATTCTCTCAAAGCCCCCACGTCCACGAGAATCACACGCTTCCTCTACTCCATTTTTCAAGCAGTCTGCAAGAAATCCAAAAGTGTCGAAAATGGTGCTTTTTCCCACACCGTTTTTACCGATGACTGCTGTCATTGACGTTAATGGCTTGGCATTCTGTGTGTTCCACAACTTTCCCAAAGTGATATCGCGAAGAACTCTATAATTTCTTACCCTAAAGCCTTCTACTTTAGACATTTAAGCCCCTTTGCTCAACTAAAAGTAATCCTACAAGTTGCTCCAATTATCTGACAATTCGATAAATTTAACACTATATTTCATTTTCTTTATGCCGTTCCACCACGATGCTCAGTTTTTACCCAGCGCGATCGCTCTTTTTGCACACACATCTTTAAAGTCGTCACAATCATCACAGGAATCCAATGCACCATGTAGAATGACCCTTGAATTGTTGCCCAAAGCAAAGACCATCCTCGTAAATTTTGAAATTGGTAAAGTCCAGCAATAAAGGCAATTGTCAGAATGATGCTGAGTAGTGTTTGCAGTGGAAACAGAACTGGATGATGGCTATATAGTATTGTCCAAACTAAGTCTGGTATTAGTCCAATTGGTAGAAGAAATTGCAATAAGAAAAACAATAATAAATCTATTTCTTTCGCCCAACCTAAAGTAAGAATTTGAGGAAAATAATCCAGGTAACGCTGATAGCCACCTTCAGCCCAACGACAGCGTTGATTCCAAAGTTTTTCCCAAGTAGTTACACCTTCTTCTTGAATTGATGGAACTGTAACAAACTCAATTTCTGCACCTGCCAAATAGAGTTTGAAACAAAGATCCAAATCATCGGTGACAGTGTTCTCATTCCAACCTTGACACTTTTCTAACAATTCCCGACGAACTAACATCCCATTACCCCGCAGTTCAGACATTCCACCAATCGCAATGCGATGGGTTTGCAGAAAGCTATCACAGCACATTTCCATCTGCTGGCAACGGGTTAAGAAATTGGTATTAGCATTAGAAATCGCTTTTCGTACTTGCACTGCACCGATCGCTTGCTTCTGAAATAAAGGTACTGTTCGCTGGAGAAAATTGGCAGGTAACTGAGCATCCGCATCGCAGACTAGAATAATTTCCCCTTGGGTAAAGGGAAACACCGCATTTAAAGCCCCTGATTTACCACCTTTTGATTCCCGTCGATGAACTTGTAAAGATGGAAATTGAGTTTGTAATTCCCTCAAAACCTGGGGGGTTTCATCGGTACTACCATCATCAACAACCCAGATATCTAGGCGATCGCTGGGATAATTCAATTGGCATAAGCTGTAAACTAGATTAGCCAAGACTGGACTTTCATTTTTAGCCGGAACTAAAATCGAGACTGGCGGTAAATAAATCTCACTCTCCATCACCGCCGCTACTGGTTTTGCTAACAGCATCCGTAATGTTTGCACAGTCAGGATGGCCGTTAATCCCAGCATCAACCATTGTGTTTCTGGTAGCCAGTGCAGCAAACTCACGCCACCCCAAACAAATAAAACTATTATGGTTGCTTTGAGACGGCGATGAAAGCTAATATTTTTACTGGGCTGATAGTTGCTTCTTCCCACTTTATTTGCTATATCCTTTCGGTTCGTGGCTTAGTCTTGCGACGTAATAATAGCATCGTCACTGCTCCCAGAAGGAAACCACCTACGCCTGCTGCAATTGCTAGAATGCGTCCCAATTGTTGAGCAGCATTTAGCACCGGGTTATTCAGTAGATTTGAGGAAAAATGCAGCGATTGAATCGTCCATTTATCTTGGAGTTTTTGCAGCACTGCTGTCCATCGCAACGCCATATCAGCCGCTTTGCCATCTTTGAAATAAAAGGATGCGATCGCCTCTCCAGAGGCAACATCTATATCTGGAGTAAGAAATGTTCTAAGAGTATCTCCCTTCAGTTGCATTTTGATATCTTTGATGGAACTGGAAAACTGCTGATTCCAGTACTTTTCAAACTCAGGAACTTTGTGAAAAATCTGGTTATCAACTGTTGTGATTGTGAAATTTGGGTGCAAGTAAGGCTGTATTTTGGCAAAATCGCGGGTGTTTAGGGCTTGCAGGGCAATGTCCCGTGTGCGAATAATTGCAGTTATCTCCTGTGGGTTGACATCTGCTAAAGCGGATTGGGGTTGATTCCAAATTACTAACACTAACAAAACACTCCAAAGTAGCTGAGTGTATTTGTATATACTTGCCTGTCTCTGTTCCATCATCTAAAAACCTGTAGATTGAGTGACACTTACCGAGAATTTTTTAATGTTACTACCCACATTCAGTACTTCTTTTTGTTGGACATAAAGAAATACAAAAAGAAGTGCTGATGAAGTCAATCAGTTTTCTCCAACCCTGATTTTAGGTTAGGTATTTTCATTAATCTATAGTTGTTGAGAATCAGCCTGTGTAAAAGCCAGGTTGTTTGAGAACTTACCGTGAAAAATCAGATAGATTAACCAGTCAACTTAATTACACCTTGGCTCACTAGATATTTGCAAGTAAGTGAGGCACAAATGCAGCACTCACGCATTAGATAGATGTTTCTATCTCTAGCCTTACCCTCAAGAATTTTCCCTTGTCAATTCGCTACGAACTTATGCAAGGTCGGTTTTAAGTATTTTTACCAGTAGTATATTTATCGATAAAATATTGAGTTTATACTTAATTTTCTGGCTTTTCATCAAAAAAGCGCATCATACTTTATAAAGTAATGTGTAATTACGTATTTTTCAGTAATAATACTGATTCATTAAGCAAGTGACTAGATTTAATGTGGTTAGTTGACAGCTAAAAGCGGTGACGACCCTCTTGAATTAACAGAATTGGTATTAACTAATAAGTACTAATGCACCAATTTGTTGGTTTTGGGATTTAACCAAAACTTACCTAACTGCACTTCAAAGCCTTTTCCAACAAGAGGTTATTCTTCATGCTGTCGAGTAACCGAATCTCCAAAGTTTGTGTTGGTGGGTCAAGTACCCATTTTTTGAGATATATGGGGATAAAGAATTCTGCTGTCTTTGTTGTACCTTCAGACCACTGTTACAAGGATTTATGACTCAAGAACAATTGACAATGACGACGCGGAACAAACTCCTGAAAATCTTGGCGATCTTTGTTTTGGCAGTGGCAGTTACCTTTTATGGGGGTCGTTATGCGATCGCTGATGAACCGCCACCCAATGCCTCAATTATCTGTGCAGAAACTAGTACTTTAGAAAAGAACTTGCGAGGCAAACTGGGCAATAAACTGCTCACATACGAAGGTTGTCCGCAAGAAATGGGCGCTTGGTATATGCTACCGATGGCCAAAAACGAAAGCGATCGGATGCAAGCTGTTCACGCAGCGCTATTACCCAACAATAAAGTCCTGATTGTCAACGGCAGCAGCAACCGCAACCGTGTCACAACAGAAGGCAAGATCGAAGACGGTGTTAATACTAAAAATTATGATGTCGTCAATAATACCTCTATCTTCGATCCCTCCCTTTCCGATTCGTTAATCGAGAATGCAAAGCTAGATTTCAACATCTCTCCTTTCCAGCGCATTGACTCACCCCTAGCAGAGATAAACGGTGAAAGCAATGACCCTTTCTGTTCCGGTCATTTACAGCTGCCCAACGGAGATGTACTATTTATCGGTGGTAGTCGAGTATATTACCCAGGTGTACGCTTCGCCGGGTCAAAACAAGCCAATATTTATCACTGGCAAGAAAAAGATTGGCAAAAACAAGACCAAAATATAAAGAGGTGGGAAAACCTGGGTTTAACCAAGGATGGTCACTGGTATCCTACCCTCATTCCTCTAGCGGACGGAGCGATCGCTTCTTTCTCAGGATTCACAGCCGATCCCTCTCAGATTGTTAGCACTCTGGTAGAAATCTACGATCCTAACTTGAAGACTTGGCAATCTATCGATGTCAAGAATCTTCCCAACAATCCGTTTCTAACTCAAATGAATGACGAGAGCTTCGGCTCTGACATCATAGACCTCTATGCCCGCATACTACCCACCAAACAGAAAAACCGATTCATCATCACTGGTGATGGCGGTGGTAAAAATGAACCGAAGATTGCACACGCAAGTACCCACAGCTATTTTGTAACGTTCAATAAAGATCAGGATGGAAAGTATTCCATTAGCTTCGAGCCAGGCCCCGATAGACTAGCAATCAACAAAGTCTATGGCACTGCTGTTCTCGACCCTAGTTCTCCTAACGGGGATGTTTTGTTATTGGGTGGCATCATGGGTACCAATAACATTGGCATTGGCCCTGGAAAAGATGTTATCAAGGGAGCAAGCATCACTGCTAGCCTAGAGCGTTGGAAAGCACCACAAGACGCTAGTACTAAAGGTTCATGGGAGATCGATAATGACTTCTTGGCCAAAATCGATGAAGACATTCTGCTGAATACTGAGGATATTGTCGATGGCAAGGTGAAGAAATTTCCACTGAATTATAAGTATGTGAAACAGTCTTCAAAATTGGGTCGCTATGGCAAACGAGCTATGGAACAGGCGGTTATTCTACCCACCAAAGAAATTTTGGTGGTCAATGGAGGTAACTACGCCGAAACTCGTCCGGCTTACAACCCCACCCTGTTGATTCCCGATGCGACTAAAACCGGACACCAAGGCTTCCGTACCAAGCTGATGAACCCGGATGTTGAACCCAGACTTTATCACAATACCGCTTTGCTGTTGCCAGATGCACGGGTGTTAGTCATGGGTGGTAATAACTCTCGTGCTGCCAGATTTGATAAAGATGGAACAGTTCGTCTGGATACCAAGAACGATTTTGCCTTTGTTAATAAAGGCACTGATGGCAATAGCGGTGAAATATGGCAACATGCGATCTTTTACCCACCCTATCTCTTCGGAGAGAGCGATCGCCCAGAAATTGCGATCGCTCCTGAAAAACTCCAATACGGTGCGTCTCAAACTATCTCTGTGAGCAATGCCTCTACAGATCAACCAGGTTCTATAGTGCTTGTAAAATTGGGATCTGTCACCCACTCCTTTGACAATGGTCAACGATTGGTAGATATCCAGATCGACAAAAAACAGATTAAATACTTGAGCGCACAAGAGCAACAACTAGGTGGCTTGAAATACAACGCTAGCATTCCCTTCACCGCTCCCACCAACGACCACTTTACTCCACCTGGCTACTACATGCTGTTCTACATCAATAGTGCCGGAAAGCCTTCTCACGCCAAGATTGTGCAATTAGTAAATAGCTAATTTTCTCCTCATTAATTCTTCCAGAAGGGAGATATTTGTAGTAGCTTTTTAGACTGACTACTTATCAAATATCTCCCAGTCCGGCTCTCAACCAGACAAGTTTAGATAAATCTGAAGTCAGGAGTTATTTATGACAAGCGAAATCAAGGAAATTGACATCAATCAAATCGTCGAAATTGCTACCCCTTTTGATGATTTTGAACATGAAGCCCTATTGGATGAGATACAGGGCAACATCCTCAAGTCACACGGACGCAACCATGCTGTTTATTTGTTCTTAAAATTCGAAAACGACATTGAAGCCGCCAAGCAATGGATTGGCAGTTTTACTCACAGGTATGTCACCTCAGCCCTGGAGCAAGCCGAGCAAGGAAAGCTGTATCGCCAGAAGAAAGATGTACCAGGTAAACTATTTGCCAACTTCTTCTTGACAAGGGCTGGTTATATGCATTTAGGGTATGGCTACCAGAATCTGCCCAATGAAGACGCATTTCGGCAAGGGATGAAAGATCCTAATATGCAGAATGAACTCGGCGATGATTCTAATCAATGGGAGGATGGGTTTAAAAATAATGAAATTCATGCTCTCGTTTTACTCGCAGCTGATAAGATAGTCGGCCCCAGAACTGAAGAAGCAAAGCTTGAGGAGCGGAGGGATCAGAGTAAGCTGTGTCAGCAACCTGCTCTCTTGAAATACAAAGTAGAGGCAATAAAAGGAGAGTTGAATGCGATCGCCTCTATTGTCCACGAGCAAATAGGTTATGTCCTCAGAGATGAAAATTCTGGAGAAGAGATCGAACACTTCGGATTCCGAGATGGAGTCAGTCAACCGTTGTTTCTGAAGCGCGATGTTGACAAAGAAAAAGAACATAGCGACTTTACCAAATGGGACCCCCGCGCACCCCTAAGCTTGGTTTTATTCAAAGATCCCTTGGGTAAAAAACAGGAAAGTTACGGTAGCTTCTTGGTGTTCCGTAAACTGGAGCAGAACGTTAAAGCCTGGAATCAAGATGTTGTCAAAAACCTGGCCGAGAAGCTGAAAGGTTCAGGAGAACTAAATGCACCTTTAGCTGGAGCATACACTATGGGACGCTTCCAGAATGGAACACCAGTAGCGATCGCTCAGACACCAAGCGAGGATAAAAAGCCTGAAACTAACAACTTTAATTATCAAGATGATCCGCAAGGTTTCAAGTGTCCTTTCCATGCCCACACTCGCAAGGTCAATCCCCGTGGGGATACATTAGCCCTTGTATCAATCCCTCTAGAAGAGGAGAAGATGCATCGGATTGCCCGTCGTGCAATTAACTATGGCACTCTCCCCAGCAAAGAGCCAGAAAACGATGCTGGACTGCTGTTTATGAGCTTTCAAGCCAGTTTAATGAACCAGTTCAACTTCATGCAGAAGGCATGGGCTAAAGAAAGGAACTTTATCAAGCGAGATGTGGGAACAGATGTAGTTATTGGTGTAGAAAAGAAAGGAGACGATAACACAGCTGTCACGGAGACATACAGTTGGCCAACTAAGTGGGGCGGTGAAGAGCAGACTGAAGCTGACTTTAGCCATTGGGTAACTATGAAAGGCGGAGAATTTTTCTTTACCCCTTGTATGAGTTTCCTCAAGTCGCTTGCTCCCGAACCCAGTCGCCATATAGAATTTCGCGGAGTTCCTAAAAAAGAGATCGAAGCGGCTCAAGGCATAATCAATGAACTTCAAAATTACAAGCAGAAGAACTGGGCAATTGGTCTAAACGGAGATACCGTTGAGCCGGACGGATTTCTCACCTTCTTCAACCAGCGAAAGCTCTCATTTAAGTTTTATTTGCAAAATCGAGTTGGATTGGGTGAATACTCGGCTTACGATGATAATATCAAAACCCTAAATCGCTACATCGCAGATGTAATCGATCAAGAGAGCGATGCTTGCGAATATAAGATCGCTGAACTAGAGGAATACAAAGACCGGAAGTGGGCAATTGGTCTCAATGGAGATACCAGTGAGCCAGACGGATTTGTTAATTTCTTTGGCGAACGAGAGCTACCATTCAAGTTCTTTGTGCAAAATCAACGTGTTTCATTGGGTGATTACTCTGCCTACGATAATAATATCAATACGCTGAATAACTACATTAGTTCCCTCAAATAGTTAGTAGGTTTTAACGGAGTTTACTTTATCAAATAGAATTCAGGAGTCAGGAGTCAGAATTCAGAATGAATTCTGTATGAGTGGCGGATAGCGCAGCGTAAAGCCTTCGGCATGGCTTCGCTTAAAGCGAGTCTGCGAGCGTCTGAATAATCGGGTTTAATACCCCCACCAAATCGTAGATTTGGTGGTCAACAAGAAAGTCGTGGGACTGAATCCCCGACTGATAGCGGAGCGGTAGCGAGTATTCGAGCGTCGCGTCTTGATTCTGACTCCTGTTAGCGGTAGCGGGGCGTTTAGCCCATTCTGACTTCTGAATTCTTCTTCAATCAAATGACCGTTGTGAAGTGCGATCGCTTTCCTGATCGCACTTCACCCTATATCACTCAATTTTTTATTTTGTCATAGGCGCGATCGCTCATAAGATTTTTGTCTTACGAAGCAAGACGACGTAACACCATGAGAGAGCGGTCTGTAACTGGCACAGTTTGCTCACCCATAACCAACTTTCCTGGGCTAAGGAAGCGAGATTCATTGGTGTCAATAACTATTTCCCATTCCCTGTCTTTGAAAACATTGGGTAAAGCAAACTCAATCGTTTCGTAGTGAGCATTAAAGAATAGCAGAAAGCTCTCATCAATAATCCGTTCACCACGGCGGCCAGGAGTAACAATGCCCTCGCCATTCAAGAAAATTTCCATAGCTTTGGCATAACTAACTAGCCACTGCTTTTCAGTCATTTCGCTGCCATCGTCATTAAACCAACCAATATCACTGATCCCAAAACCGTGAATAGGACGGCCTTGAAACCACTTACGCCGCCGAAATACTGGATGCTGATGACGAAAATAAATCAGTTCGCGGGCAAAATCTAGTAGTTCGGAATTAGACTTTTGTAAACTCCAATCGCGCCAGGCAATTTCATTATCTTGGCAGTATACATTGTTGTTACCCTTCTGAGTGCAACCAATTTCATCTCCTCCTAATAGCATGGGTATGCCTTGAGACAGCATTAGAGTTGCTAAAAAGTTGCGTCGCTGACGTTGCCGTAAGCGGATTACATCTGGGTCATTGGTTTCTCCTTCTACACCGCAATTCCAAGAGCGGTTATGGCTTTCCCCATCCCGGCTATCTTCGCCGTTGTCCTGATTATGCTTTTCGTTGTAGCTGACCAAATCATTGAGTGTGAAGCCATCATGAGCAGTGATGAAATTAATACTGGCACTGGGATTACGCCCGTTTGCTTGGTAAAGATCAGGGCTGCCGGTAAAACAGTAAGCAAATTGTCCGAGGCTATCATCCTCACCACGCCAAAAATCCCGCACAGTATCACGATATCTGCCATTCCATTCAGACCAACGTAAAGGAAAATTGCCAACTTGATAACCGCCTTCTCCTAAATCCCAAGGTTCAGCAATCAGCTTTACATCTGCCAGAACTGGATCTTGATGAATAATATCAAAAAAAGCTGCGAGATTATCTACTTCATATAGTTCTCGCGCTAATGCTGAGGCTAAATCAAACCTAAAGCCATCAATATGCATTTCTGTTACCCAATAGCGCAGACTATCCATGATTAACTTCAGAACTTGGGCATGACGCACATTGAGGGAGTTGCCGCAGCCTGTGAAGTCCATGTTGTAACGGGAATTATCTTTGACCAAGCGGTAGTACACAGCATTATCGATGCCTCGTAGCGATAATGTTGGCCCTAAATGATTGCCTTCGCCAGTGTGGTTATAAACTACATCTAAAATTACTTCAATGCCAGCAGAGTGTAAGTCCTTGACCATCTGCTTAAACTCGGTCACTTGTTGTCCGACTGAGCCACTAGCACTGTAACCAGAGTAGGGGGTGAAATAATTAATAGAATCGTAGCCCCAATAGTTTTTGAGTCCTTTATTTACCAGAAATCCTGGAGAAGATAAAAAGTGATGTACAGGCATCAATTCCACAGATGTGATTCCTAGTTGTTGGAGATATTGAATTGCAACTGGATGTGCCAGCCCTGCATAAGTACCATGTAATTCTTCTGGAATTTCTGGGTGTAATTTAGTAAAACCTCTAACGTGAGTTTCATAAATAATAGTTTCGTGCCACGGTATAGAAAGTAGTTTGTCATCTCCCCAATCAAAAGACTGATCGACAACAATACACTTCGGCATAGTTTCGGCATTATCTAAATCGGAAAAAGCTAGGTCTTGTTCTGGCGCATCTAAAGAGTAGCCAAAAATAGCTGCGGTATCGCTAATTTCCCCATCAATTGCCTTGGCATAAGGATCAATTAATAGTTTATTAGGGTTAAAGCGATGACCAAGTTCTGGGGCCCAAGGGCCATGTACTCTAAATCCATAGCGTTGCCCAGGCCCTACTCCTGGTAGATAAGCGTGCCAAACAAAATTATTTTTTTCTGTTAAAGGCAAGCGATTTTCATGATTATCAGCATCAAATAAACAAAGTTCTACACCTGTTGCATTTTCCGAAAACAAAGCAAAATTCGTACCTTTTCCATCCCAACTAGCACCCAAGGGATATACATTCCCAGGCCATACAGCTACATACATAAGCAAATTACCAAGAACTAAATTTACTGTTAACAAAAAACTTGAATATGTGTTTGATAGTAATTAATACAAGTTAGTTTTCAGGCTAAACTTAATAAGTTTAAATTAACGAAAGATTACTATTTTATTGCAATTATTATCTTTAAAAAGTCTTAAAATTTGATGATAGCAAGGATCGCTTTACATTTAAAAATATAATTTTCATCGTTAATTAATAATATTGGCAACATCCTTGTTACTTTTGAATTCATAAATATGCTAATAAGTTTCTCTGCAAATCTTTTCAGCTTCATAAATTTATGAAAAATAGCAAATACCGGCATCTACCAAAATGAATAAATTTATTTATATCAGCATGTATATTTACTTAAAATATCTTTTATGAGACCATCATATAGATTTTTGCATTTACTTAATTGTTGTAATATTTGTATCTGATAGCAAGCATCATCTTGAGTGATAGAATTGCCAAATAAATATGGTTTTCCTTTAGCCAATGCGTTGTTGTGGAAGAAATAAATTTACTATTTAGTAAGTGTATTGATATATTTTGGGCAACAAAAGATGCAGATAAAAGTGAAACTACGGAATAAGAGCGAGAATACGTTGAATTTTAAAGAGAAATATCACCTTACCATTTATGCCATCCGGTATATGTGCGCGAACCGCAGTAGCGATTAACTTAAATATTAGGAAAATGCGCGAATTGGCTGGGTTTAAGCTAAAGGGAATCAATAAAAGCCCTTTGGCTTACTTTTTTAGCAATGGTATTTATGTACAGTCTCACTGCCTGCGTTTTTCAGCCTTGGGAGTTTTTAACAAGCTCACTAAGTTGTTATGCTGCCGTGTTCAGGCAAAATCTCTAGTAGAAATCAACCTGTATTAGGAAGTGGGCGATGCACATTGGATTTCTCAACCCTCAAGGCAATTTTGATTCAAACAATAGTCACATAAGCAAACACCCAGATTTTGGGGGTCAACTGATCTACGTTAAGCAAGTCGCTATAGCGATAGCCGAAAAGGGACACAAAGTAGATATTCTCACCCGTCAAATTATTGATCCGGAATGGCCAGAATTTGCCGAAGCGTTTGACACTTATCCAGGAATCGATAACGTCCGCATTATCCGCTTACCAGCTGGGCCAAAAGAATTTCTTCCCAAAGAGTTGTTATGGACTCATCTGATTAGTGATTGGGTACCCAATATCTTGAAATTTTATCAACAGCAAGGTGGCTTACCCGATGCTATGACTGCTCACTACGCCGATGGAGGGCTGTGTGGCGTTTTAATTGAAGAGGATACAGGCATACCTTTTACCTTTACTGCTCATTCTCTCGGTGCCCAAAAGATGGACAAGCTGGAAGTCACTTCAGAGAACTTGTTAGAAATAGATGAGCAATTCCATTTTAAATATCGCATCCTAGCCGAACGCTTGAGCATGAATCGCTCGGTCGTTAATATCACCAGTACACGACAAGAACGCTTTCAACAGTATTCTCATCGAGTCTATAGGAGTGCAGTGGATGTAGACAACGACAACCGCTTTGCAGTGATTCCACCGGGAGCAGATTTCTCGATTTTCGGTGCAAAGGCACGTTCCGAAAATGAGAAAGCAACTGAAGAATTCATTCAGGAGCGATTGGCACGGGACATTGCAGAAGCCCGTCGAGATTTGCCTGTCATCGTAGCATCCAGTCGATTAGAGCTTAAAAAAAACATATTAGGGCTAGTGCAAGCCTTCGCAATCAGTCCAACACTTCAGGAACGAGCTAACTTGATGTTACTTACAGGGGGACTGGACGATCCCTTACGAGAAGAGGCTAGTGACAGCATAGCTGAAGAGGTATTAGCCCCCATTCGAGAGGTGGTGAAGGAAAACGACTTGTGGGGCAAGATTAGTGCATTTGGCTTGTCAGATCAGTCTCAAGAGTCACTGGCAGCAGCCTATCGGTTTATGGTTAAACGCCGCTCGGTATTTGCGCTGACAGCACTTTACGAACCCTTTGGACTTGCTCCTTTAGAAGCAGCAGTTGCAGGTTTACCAGTGGTAGCAACCAAGAACGGTGGCCCTAGCGAAAGCTTGCGACAGGGAAATAAGGAATATGGCATACTCGTAGACCCAGAAGATCCTGCTGATATTGCACGAGGCTTAGAGCGGGTGCTATGTGATGCTCAGGAGTGGGACTATTTTGCCCAAGCTGGTCAGCAACGGGTTCTGAAGACGTACAGTTGGGAATCTACTGCTGAAAACTACCTGACTTTGCTTGAGCAGATTCTGTCTTTACCGGAAAACCGCGATCGCGCTGAACTCCTGCCCATCCATCCCTACTTTCGTAATCCAGAATCGCAGACCGATGTTTCTTTGGAAGAATTAAGCGACCTCTACTTTGGAACCAATCAAAAGGCATGAAGCCTTGATTTCTCACAAGTGAGAAATCCGGGTAAGGATCGTGGATTAAATAATGTGCAATTCTGGTTTAGTAACTTATGTAAAGTTAATTAATTTTGAGGTGTAGCCGCACAGGTTAATGCTGTTTGTACCTGATTCGGAGATTGATTGCTAATTAATTCAATTTTACCTTGGGCATTACGTCGCCAAGATGTAGCTTGAACAAGTATTTCTGGGGGTTTCTGTATTTGTGCTTTGACTGGTTGTGTTGTGTGGAATGCAGAGATGTCGCGGATGTCTGACCAAGTGCGATCGCTGCTAATTTCCTGTGTCGGATTTTGCGGTATCCCACCTCTACCTGTGGCGACAAAACTACTACCACTGCTATTTGCACATCCTGTAGCGATTTTTTGGGAAGAATCACTAACATTCACAGGTAATTCCACTAGACCAGAATTGGGGTCAAAACCAATAGTATTAACGTTAACTGTACCATTCACTCCAAATTGTGAACTGGCGGTGATATCATTTTCTGATGTTAGTTTCGGACGATATTCTAAACCAAAAATCCCCTGAGTTGTAATTTCAATATTTCCGCCTTTACCTTGGAAAGCATTGGCAATGATATCGCTGTTTTCCCAGCCGAGAATGATAGGTGAATTAATGGTAATGTTACCACCATTGCCAGCAGCACCAGCTTCAGCATTAATGAAGCTACCATTACGTATGAGCAAATAATCGCGGAGTTGGAGATTGATATTGCCTCCTTGACCAGCTTTTGTAGATGCGGAAAGACTACCATTGTTGAGATATAAGGTATTGGCATTAACGTTTAAGGTACCTGCATCACCTTGAACTTCATTTTCGACAAAAACTCTTGCCCCATCACGAATGGTTAATTTAGGAGTATTAATTGTGACACTCCCTGCATTTGCCTTGGAGGTACTATTGTTATTAATATTTGTAGAAGTTCTCAGTAGAAATAAACGGGCGATCGCCCCAATATAACTAGGATTTTCTGCGTCTTTCATGCCCCTAACATCAATTGACTCAGTGGCATTAATGGTAAGATCGCCAGCATTCCCACTACTCACACTCGAAACTGAGACTAAACCCCCATCTTGTATTGACAATTTCCGGGTATCTAAATGTAAGTCTCCTGCATCTCCTGGGCCAAAAGTATTCGCTGATAGCAAGCTGATAAAAAGCGATCCAGGAGGAGAATCCAGACTTGAGACATTCACAGTATCAGCAGTAACTTTAACATTGCCACTCTGACCGCTAGAAAAGCTCCTAGTACCAACATTAGCACCGCCCAAAATTGAAAGGCTATCAGTAGAAATCGATAAATCTCCACCTTGCTTAGTTCCAAAAGCAGCAGCAACAAGCACACCAAATATCGGAACAGTAGATGGATCTTTCGGATCGACCCCACCCACAGACACTGCATTGGCATTGATTGTGATGTTACCACCACGGGCCGAATTATAGCTACGATCCATAACAATTGCCCCACGATCAATGGTCAATGTTGGAGTTGTAATCACAATATTTCCTGCGGTTCCTGATAGTAGAGCTTCATTGACTATGCCACTGGAACTGCGAAAATCTGAGGATTTACCAACTACTTGTAGCGATTCTGTAGCATTAACAGTAATATCACCTGCTTTACTGTTGCCTAAATTTTGTACTACCAGCAAAGAACCATCCTGAAGATCGATCTGTTTACCCTGAAGTTGAATCGAACCGGGGCTGGTTCCGCGTACAGATGCAACAGCACCTTGACTCATTTGGATATTACCAAAGCTAGAGCCAATACTTGGATAGCTAAACGTTAATGCTTGCGGCGTGAGATGGATATTTGCACTGCCTTGGGTAATGCTGCCAAGTTCAATTCGTCCTCCTGGTGCAGAAAGAAAGCTACTATCGAGAACGAGATCACCACCTATCAAAGCTAGTGTTTTTTCAGGTAAAACCTGCAAGCCATTTGTACTAGTTAATCCAGAAACAGAAGTTGTGGGGTTCAATCTACTATTATTTCCCACTCCTTGCACGGAAATAGTTCCCGGATTGCCCCCAAGTTGTAACCCTACAGGTACACTCATAGTTAACAATGGGGATTTAGTTATGTTGGTGCTAAACTCGTTGCCATCAGCAAATTGGATGCTATTAGCGGTTGTGCCGACAAAAGAACCACCAACGTTTAAGCTAGCATTTGCACCAAATATAATCCCCGCCGGGTTCAGTAAGAAAAGGTTAACACCGCTATTAGTGTTGATGGAACCATTAATATAAGAAATACTATTACCAGTGATGCGACTAAAAATATTTTGAATGTTGGAATTATGACTGAAAGTTGCAGAACCACCTGTAGGAATAGAGAATTGGCTAAAGCTGTGAAATAAATTATTGCTAACAACAGTACCGCCAGTAATGTTGTAACTATTACTGCCAGACACAGTGGTGTTGAGAGTACCATCAGGCGTGATCTGCGCTTGAACATTGCTGTTACCAATAGCAGATATGTAGATTGCACCAATTAAGCTTAAGTTAGCAAAAGTTATTTTCATCAGCCAAATTTGTAATTATTTATCTTGTGTCTAGTTTTCCCAAAATGAATTGAGCAATTTGGGTAGCTGTGTAATATTATGGTGAGTTTTTTTCAGTTTTGATTAATAGCAGCACAAATTAATAATGGTGGTAAATAATTTCTTGGTTGAGGCAGGTAGGGGGAGCAGGGGGAGATGTAGGCAGAGGAGTGTGGGGAGTGTGGGGAGTGTGCGGGGTCAGATTTCTTCCCCATCCTCCCACACCTCCCACACTCCTTGATTTCTCACAAGTGAGAAATCAAGGTCTTACCTCCCCTGCTTATCCGAACCGTATTGCTTCATATCTCCAACAATTTAACTTTGAGTTTGAGCCAGAATTGGTAAGCTAATGACAAATTCTGTTCCTTCACCTGGAGTAGAATTTACATTTAGATTGCCACTGTGTTTTTCTACAACAATAGAATGAGCGATCGCTAATCCTAATCCCGTTCCTTTACCAACACCTTTAGTAGTAAACAAATGCTCAAATATTTTTTCTTTGACTGACTCGCTCATCCCCACCCCATTATCAGCAATCTTTACTTCAACCTGTTGATATTTTAAGGAGGTGGTAATTGTAATTCGATTCGGATTAGCTTTAATATCCTCAAATGTCCGATCTGTATTTGATTCATCCAAGGCATCAATAGAATTCGCTAGGATATTCATAAATACTTGATTTAATTGCCCTGGAAAGCATTCAACTGGCGGCAAGTTACTGTAGTTAGTCACTACCTCAATTGCTGGACGATGTTCATTAGCTTTGAGACGATGTTTTAAAATTAGAATTGTACTATCAATCCCTTCGTGAATGTTAAATGGAACTTTGTAATCTCTATCGGCACGAGAAAAAGTTCGGAGGCTCGTACTAATATTTTCTAGCCTCTCACAGGCCATAGTCATCGAATCAATTATCTTGGGTAAGTCTTCTAATGTATAATCTAAATCAATTTCTTCAGCATGGTTGATGATTTCATCCCCCGGCTCGGAAAACTTTTCTTGATACAGTTTTAAGTGTTCAGAAATATCAAGAAATATGGGTTTTGCTTGTTTGAGACTGGCAGCAATAAAGCCCAAAGGATTATTCATTTCGTGAGCTACCCCAGCCACTAAGTTACCCAATGCAGACATTTTTTCGCTCTGGACGATTTGTAATTGAGCTTGTTGCAAATCTTCTAAAGCTTGCCCGGCTTGCTGATAAAGTTTGGCATTTTCTAAGGCAATTGCTGCTTGGGAAGATAGTAGGTTAATTACTTGTAAACGATTAGTAGTAAATACCCCTTGATTCAGTTGATTTTCTAGGTAGATAATCCCCACCAAATGACCTTGGTTAATAATGGGTGTACATAATACACTTTGAGGTTGATGTAGGAGCATATATTCCCCAATGACACCGGGAATATTTGTTTTGCAATTATCTATGATGACAGTTTCTTGAGTATTTTTAACGTAATTGATCAGTTTTATGGGAATATCTTGACAAGTGTCTAGTAGTTGTGAATCAAGAATGGTTTTGACATCAGTCTGAGAATTTGACTGTTGATCGATAAAGGTAATTGCCCGTACTTGCCAAATATCTTCTTGAGGAAGAATTAATACAGATGTTTTTGCACCTGAATTTTCTAGGATAATGCGGGTGAGGCTGCTGATGAGTACATCTAATTCGATACAACTAGAGATAGTTTGAGCGGCTTTGAGAATGCAGGTCAAATCTAGAGTATCAGAAATATTAGTACTGCTGGTAGCGCAAGTAGATATACTGCCAATAGTGGTTATGCTTTCTAAGGGATTAAAGTAGAATTCTTGCTGTTGCAAAATGGGTTTGAGTAATTTGGGATAGCGTTTTTCCAAATCATCAGTTTTGGCTTTTGCTCCCCAACGGGCATAGCAGTAATATGCCTGTTGCAGATATCCTTCTGCGGCTTTTTCTTTACCCCATTCTAGGTAAAATTTGGCAGCAAGCTCGTTAGCGATTGCTGTTTCCTGAATATAGTCATTGGCGATCGCTTCTTGGATAGCGATTTCATAATAATCTGCGGCTTGTACGCGATCGCCAGTTACACGAGCTTGTTCAGCCAAAACTAAATTGTACTTATGCTGATAATTGACTGGCGCATGATTTGCCCATTCTTGCATTTTTGCTTGGTTTTCAGCTACTTTCTGGAGATAAAGCTGTTGCTGTGCTTCATTTACCTGAGAACAAAGAGCTAACAAACTCAAAGATTGATAGAAATTTCGCAAAGGAACAATTAATAAGCCTGCTGCTCCCTGCTCATACTGCTCAAATTTTTGGGAATATTCCCAAGCAGGTTCGTATTCGCCAAAAAGATAAGCTAGAAGAGTTTTTGCTAGATAGACATAACAAATCCCATTAATATTGTTAGTTGCAATCAAAGTTGGTAACATCTCTTCTTCGTGAAAATGCTTACCAATTAAACAGCAGGGATTAACCACTTCTCCTTGTAAATTTAAAACTGTCTGCCGCCAAATATTTCCCCAAACTAGAGATACTTCTTGTTTAAGTTGCTGCATTAGGTCGCAATATTTATCTGCCTCCAGCACTGCATTTTCTAGGTTTTCTCCACTCCAAAAGAGAAACTGACTATAGCAATTAGCACAATAACCAACATATTCTAAATTTCCAGTTTCTAATCCACTTTGTAACCCATCTAAAAATAAACCTAACGTGGATTTAATTGAATCTTTCCAGTGTTTAATAAATAGGCTAAATGTGAGATAAACTCTACTTTTAAGTTCTTTATTTTGAAATTTATCTAAAAGTTGTATTGCCAGTTTACCAAAGCTATATCCATCTTCAATTGCACCAATACTGCACAAAAATAATCCATAGAGACTGTAAGCTACAGCAGCCTGTGGTGAGTTGCCAGATTGAATACAAATTTTGATCATTGTAAAAATCTTGATTGGCAGCAACATCGGTTTGGCTATATAAACCGGGGCAAATAAACCCGATAAAATGCGAAGTGCGACTAATTTTTTGGGATCGGTTATTTCTGGCATATCTGCCAATGCTGCAATTGATTGATGAACTAACATTTGTTGCAACTGGTCATATTCATCAAAAATCATTTGAGTGTTACCATCTTCAGGTAAGGTCAAATCTAGTAATTGGAGTGCTTCTCTACCTGTGGCTATTGCTTCAATGAATTTATTTTGCGCCGTATAAGACTGGATTTGAATCTCATAAGTACGAACTTTTTCTAATGGAGATTTGGCGTTTTTGAGGATAATATCTACTAATGATTTGGATGACTCAAAGTTTGTATTCAGATATTCTGCTTCAGCCGCAGATTCGTAAACAGCAAGGGTCAAATCGTAGCTACTTTGCCAAGCATTTATCGGTAATAGAAGCATTGCAACTTTTAAATATTCTACTGCTGTTGCATAAGCAGTTGAGTTTTTGGCTTTACAACCAGCTATTAGATTTAATCGGGCCAGATGTTCTCGTTCGCCAGGTTCTTCCAACAACTCCAATCCGTAATTGAATTGGTTAACGATCGCAAAAATGCCTTCCTCTTGCTGATGCAAAGGTGTATTTTCCAACAACAATCGACCAATTTGCAGGTGTGTTGACTGTTTTTGTGCTTCTGGAATCAGTGAATAAGCAGCTTGCTGGACGCGATCGTGTAAAAATTTATATAGAACCCATTTGACATCTTATGAGGTTTTGAATTAAGGTACTCCTCAGCATCAAAAATCCAATACTAATGGCGTATTCCAGCAACCTCACTGATGCAGAATGGGAAATTTTTGAACCCTTATTGCAAGAGATATTACCGACTAAGAAGCAGACTCGACCGACCAACTGGCCAAAGCGAGATATCTTCAATGGAATTCTCTATCAACTAAAAAATGGATGCAATTGGCAAGACTTACCTAAAGACTTCCCGCCTTATTCCACCGTATATTGGCACTACAAACAGTGGCGAGCAGCAGGGGTATTTGAGGAACTGATGAGTGTATTACATGGACAAGTCCGTGAACAGGTAAAAAAAAACCGCACTGGACGACGTTGATCATCATTGACTCCCAAGCAGTGAAAAATACCTGTAATGCCAGTGTGGAGTCGAAAGGTTTTTGTTTCTACAAAGCCACCAACGGTATTAAAAGGCATTTGGCTATTGACACCCTTGGGTTTCCCTTCTTTACGCACTGTACTCGCGCCAATGTCTCGGATGATGCCGGATTAATTGAGATGTTTACTCTCAACATCGACTACTTCAAGTCAAAACCTATCGATATTCCCAAGATCACTATCCTGCTAGATCATGGGTATCACCCAGAATACTTGACTCAGGAGTTAGAGCAGATTTACCCAGAGATCATGACCAAAATTCAGTTTCAACTTTCTACGAAACCCTCAAAACAAGAGAAAGCGGCACAAGAAAAATCTGGATTTGTTCCGGCAATAGCCAGATGGGTAATTGAACGCTCCAATGCTTGGATGGAGCGCTGTAAAATTCTGGTTAAGAACTTTGAACGAACCCTCGTTAGTGCCACTGCCAAACTCAATCTCTGTTTCATCAGGCTAATGATTAAGAGGCTTGCAGCACCTTCTTAGATGTCAAATGGGTTCTATACAACCATCCCAGAATGTTCTTGAGTAGCTGCTTGATTGTCTGAACCAACAAAAAACTTATAAACCTCACTTTGCGGCAAAATTAACCCTTCTTGCAAAGCCTTCCACAAACAATCTGCGGTTTCTACCTCCGATTGTTTGGAAACAATCGCTAATATTTTTAAATCGAATTGATTCCGAATACAAGCCGCTAGCTTCAATTGTTGTTGAGTTGCTTCTGGTAGTCTTCGTAATTGGAAGACCATAAACTCAACAACATCATCTGCTAAAGTTTGCTGATTTATTTGGGAAATATCACATTCCCAACATCCCTCTACAAAATTGAATTGAATTAGACGGTCTTGATGTAATGATTTGAGAATCTGAGTTGCAAAAAATGGATTGCCTTGAGCTTTACGATCGACCAATTGCGAAAGAGATAATGCCACATCCTCTGCACAATTTAACGTGTCTGCTACCAGTTGATTCAATTGTAATTGGTTTAGTGGTTTCAGGTTAAGGCTATTTACAGTTACACTTGTTTTACGAATTTCATCCAACATCACCATCAACGGATGTGCTGGAAATACTTCATTATCTCGATACGCACCAATTAACAATAAATATCCCTGGTTAGCTTCATTCGTTAATAACTGTATGAGTTTTAATGAAGCCGAATCTACCCACTGTAAGTCATCTAAAAATATTACTAAAGGATGGTCTTTAGTTGTAAATACTTGGAGAAATTTCTGAAATAATAAATTAAATCGGTTTTGGGCGGCGTTACCTGATAACTCTGGTGCAGGGGGCTGTTTGCCAATAATTCTTTCTAATTCAGGAATTACTTCAATGATTACTTGACCATCTTCACCTAATGCTTGAACAATTTTATTTTTCCATTCTTGTATTTTAATACTGCTTTCTGCTAGTAACTGCTCCATAAAATGACGGAAAGCTTGAACAAATGCCGAGAAAGGAATATTCCGATTAAAGTAAGGATTCAGGTCTAAACGAGAGGAATTAAAGAAGGGGTCTGCACAGAAGAGTTAACCATCGCTTTGATAGCTTGGTCAAAAAACTCAATTACAGAGCGTCCTTGACGGCGACAAGTTTGTATAACAGTCAATAAATTAGCAGTATCTTGGAATCGCTTCATAGAACGAGAACCACCACTGACTTTTCGTTTTGTGACTGCTAAACGTAATGTTCGTTCTGCTAAATTATTATCAGGGGGTATGTCCGGGTGGTCTAAGAAATACCACCATTGATGAGCTTTATTACGTAAGGAGCGTAAAAGTTTACCAGCTTCTCCTCCAGCTTTATCAATCCATGAATGAATGGAAGATTCAACTTTTATTTTAAACTCGGATGCCCAACTCCAGAACTCATCAATGTTTTTAGTTTGTTGGAAGAGAGCATAGTTTTTAAAACCTTCATCTATCAGGCTGACAAATGCTGACCCAATCTCTTTGTTATTCAAGCCAGGAATTAAGATGAGTTTCTTGAAGTGACGGCGTAAATGCGCCTGACATTTCTGTTGGGCTTTCACCGGATAACCGTTATAAGCACTAAAGTCATCAGAACTGAGTACACCAGAGTAACTTGAACCCAAAATTGCCTCTAATTCGGCGCGAGAACGAGTATCAGCCGCATGAAATAAAGCGAAATCGGTATTGGCAAAAATCCATAACCATTCTTTTACCCCTTTGATTACCCAAGGTGTTTCATCCGAATGGATATTCGGCTGGGTTTGTTTTATCCACTCTTTAAGGTTGTCAATACTTTGAGCTACGGCACCATCTATTCGTTCATTTGTGGCTACTAAAGTCCCGACTCCAATTTCTATTTCACCCAGTTCCCACAACAATTCTTGTTGTTTCTCGTATGGTAAATGCCCGTAATTATTTATCCATCCCAAGAAAGCTTGCAGTCTGATTCCTATATCTTGTCCCGGTACTATTTCTGGCGACCAGTCTGCTGTTTGTTTTGACCCACACTCGCTGCAAATACAGGTATGTCTTTGATATTCTACGATTTCGATAGGTCTTTCTACCAACTGTGCTACTTGCTGGGTTTCTATTTTTATTGGTTCGTTACTGAATTCCTTTTGACCACAACAAAAACACACTTGCGGTCTTAATATCTCAAACCTATCTACTCTCCCAAAACCCTTTCTCGTTTTTCCCCGATGTCCTGGCTGTCCTCCTGGTTTCCGTTTTGGCGTTTCACTCTCCCCTGCTTCATCTTCAAGTTTTTTCTCGGTTTTTTTGAGGATGTCTGCCGACGGTGGTTTTGATGATGTTGTGCTGTCTAAGTCTCTACTAACTTTGAGTTTCTCTATTACAGATTCTAGTTCTATTACTCTGGATTTTAGCTGTTCTATAGCTTTTGCCTGCTCCATAAGCATCTCTACCAGTTGCTCTTTCTCCAACTGTTTTAGGGTTTCAGTGTCTAGTTTTAGTGGCAGGTTTTTTTCCATAATTGCTATATTCTGCTTCCCCTACCACACTTGTCAATACCCCAGCACCTGAATCCTTACAGTAATTGTAATCCCTTAGTCTGTAATTGCTGCTCGATATACTGCATTTGTTCGATAGTTTCTCCAGTAACGATCGCATAAAGTTCAGTGTAGATTTTTCCGTATTTAGCCTTCTCTAAAGCCGATAAAATAATCAAGTCTTTGCGATCTAATTCTGGTTTCAAGGTTATGAGAATTGATTCTAATGTCCCCTCCATTCGGTAGCTACTGGAGTATTTAGCTACTTCTTTTCCCAGTCGCAATAGAGTATGACGCTGCAAGCACAACGGAGTAGAACCATTAACTCGGAAATTGGCATCGATCGCGTAAAATTGTCCGTCTTGATTTTCCAGCACATCAAAGCCAATCACACCGAAATACCCCTGTTTGTGGGCATAATCACCAACGTTGGCAATCATTTCAAAGAACTTGCTCATGTCAGTTTTGCCGTAGTCAATAATTCCTCCTAAATAGTTGCCTTCTGGAGTGACGAGTTGTCCGGTAGTGCCAATGAGAGTTATCTCCCCGGCTTTGTTGACATAGAACTGTACGCAGTAATTCTGCACTTCATTCTTGACGAACTCTGAGACAATAATCGTATCAAGCAACTTAATATCAAGATATTTCTTAATTTCTTCAAGGCAGTAGTTTAGATCGCTGGGACTTTTGATGATATAAGTGCCTTCTCCTGAGAGCCCGTGGGACGTTTTAATTAAGTAGGGAAATTGTGGTAACTGAATGTCTGCGATATTGACTTGTTGCAGATTGTAGCTCTTATATTTTGGACATTGCACCCCTAGTTCTTCTAGCGTTACTTTGCTGAGTAAACGGTAATGGGTGTCTGAAGCAACAGCGTGTTTTTCAGGTTTTAGACAATCAAAAGGAAATAGAGTGATGAGTTTATCAAAGCGTTCGCTGTGGCTGAGATCGTCTAGATAAGTCGAGCAATCCATCATCTCAATATTGGAGTGCTTGAATCCCAAATGCTCTTGCCAGTATTCAAGTAGGGCCTTTGGTGGCGGAATAATCACAATTCCGGGAATGCGATCGCCTAAGACAGCCAGATTTTTCCAAGGTTCTTTCTGACAAATCTTGTCGAAGGAGGTTTTGCTGGCTTCACTACTACCATCTTGAATAAAATATTGTTTCCGGTTGGGATAAGCAGCCCAACTCGCAGTTGCAGGGTAATTTAAGATAAATCCATAAGATCCATCTATGATATCTTGAGCAAACAGATCAGAAAGAGTACTCCCTTGAAAATAATGAAAGTTATATTTTGAGTTCATCTACTCCTCCGATAAACCACATCTATAAAGGGATGCGGTTGTTTATAAAAAATGAGTCTCCTGCATTTCCAAGTAACACTAACTTGAAAAAACAAGCCTATATATTCAAACTTGAAAACTCAGATTGAATTTTGTTTTATTAAGTACGCATAAACTTAGCGTAGTGGGGCATAGACTATTACGAATTGGTATGAGTTATTTCTTGGTAAAGGCAGCCACCTTGTCTTGTCCTGCCGTCATATAAGCACAAGCCATGTGTGATGAGTTATACGCCCAGCCAACACGTCCTTGACGGTCTATGAGGATGCACCCAGCTTCACCTTTAACCTTAGAAACCAGAGCATCGATTGCCATCTGTGCTGCTTCATCTGGGTGTCTGTCTCCAGTCAAAAAATCGATCGCAGTTTTAGCCAAAACCACCGGGATAATCGACTCGCCATCACCTGTTGTTGAGCAACCGCCGAATTTATTATCAGCGTACAAGCCACAGCCAACGATCGCAGTGTCACCGACGCGACCTTGTTGCTGCTTCGTAGTACCGCCAGTTGAAGTACCAGCAGCCAAGATACCGCTAGTATCCAAAGCTACGCAACCTATGGTGTTGGGGCGATCAATCACTTCTTGATCTTCCTTCCACTGCTGCCATTGCTCCTCAGCTATTAAGTCTTCTTTTTTACACATTTCGGCACCGCAATCTCTAGCGAAGCGTTCTCCACCCCGCGCTACTAGCAGCCTGGGTTTTTCATCCATAATTTTTCGGGCAACCGAGATTGGATGACGTACACCCTGAACTGCTGCGATCGCTCCCCAACTTAAAGAGCCTTCCATAATCGCCGCGTCTAACTCCACTTCTCCGTCACTGTTGAGAGTTGCGCCAAGACCAGCGTTAAATGTCGGGTCAGCTTCCAAAACACGGGTAGCTGCTTCAACAGCTTCTACGGCAGTACCTCCACTGATTAGCACTGCCCAACCAGCTTCTACTGCTGCTGTACAGCCTGCATTGTTAGCTGCAACTTTGTCGTCTGTGATGGTTTTTGCTCCACCGTGGACAATGATGGTCGGTGTCATATAATTTCTTCCTGTTAGTATGAATTTTGTGGGACTGCAATCGCCTTCACGGGTTCGTCAATTAGTTGCAGCGATCGCAGGTGGTTCTGATTTAACTTGAGTAGCAACACAACGGATTCCCTGAACATTGCCATAAACTTTTTGCATAAAACTAACAATTTACAGTTTAGTTTTCAGATATCTATATTGTTATTTTTGTATTTTTTAATTTTGATTGAATCTACCAAGAGAAATAAGCAACTTAGCTAGATAATTATCTCAAAAGGAAGCTTTTCTAAAATGATTTATAGACCAATGAAGTATCAACCATGAAATTCTAAACATATAATGTTGCGCTGTGTGACGTAAAGCGTCTTGCCGCAGACGTATAGAGAACGCAGAGAGAAGGAAAAAATAAAAATTGCTTAAGTGAACTGTATGGCTTTATAGAGCCAAGATGATTCAGTGAACTAAATAGCATTTACGATAAAAAACGTAATATTCCATATTCTTCGTTTCACAAATAGGAAATAAACAGTGTTACCAAAAAAGACCACCGCTAGCAATCAAACTCAACGCTGGACATTTGCTCAACTTTTTGGACTGGTAAAACGTAATCCCCTGATGATTTCGCAGTGGGTGATCCTTTGGGTAGCTGTAGGTACTGCTGGTGGTCTATTCGCTGCGTTTTACTGGAATGTTTTAGAATTTTTAACTCACCATCTGCAACGATTTGAAGGTTTTAGCCTCCTGATAGTGATGCCACTCGCTGGTTTAGTTATCGGACTGGTGATTCATTTTCTGGGAAATCCCGGTGAAATCGCCGTAATTGTTGATAATATCCATTTTCGTGGCGGACGCTTAGATGTTCGCAAAAATCCCTCAATGATTCTTGCTTCTTTAATCAGCATATCGGCAGGCGGTAGTGCTGGGCCAGAAGCGCCACTAGTACAAGTAACAGGTTCTTTCGGTACTTGGGTTGCCGATCGCCTAAAACTCCAGGGTGAAGACCTCAGAACTTTGAGTTTAGCGGCGATGGCGGCTGGCTTCACAGCTTTGTTTGGCGCACCTCTTGGCGGTGCAATGTTCGCGTTGGAGATTTTGCACCATGAACATATTGTGGAATATTACGAAGCTTTGATGCCAGCCATTGTTTCAAGTTGCGCGAGTTATCTGGTATTTGCAGCAATTACACATTTGGGAATTGCACCCACTTGGCATTTTCCCCAGTACCACCTAGAAAAAATTGATGATTTTGCGATCGCGATCGTATTCGGAATCATTGGGGCGGTGGCGGGATGGATTTTTATGAGCATTTTTCGGGGCTGCGATTACTTGTTTGCTCGAATTCCTGGCCCCATTTATGTACGCACAACATTAGCAGGATTTGGGCTTGGCACTTTAGCAGCTTTATTACCCCTAACCCGTTATTTTGGACATGAAGAATTAGAGCCAGTCCTCACTACTAACTTTGGTGCTATTTTTCTCTTAACTCTTGCTCTTGGTAAAATGGCAGCCATTAGCATTACGGTAACAGGTGGGTGGCGCGGTGGATTCATCATCCCCCTGTTTTTCACTGGTGCTTGTATTGGTAAAGCAGTAGCAGTGTTAATTCCGGGGCTTAATCCCGCTCTTGCCATGATTTGTACAATGGCGGCCGTCAATGCAGCCGTAACGCGTACACCTATAAGTACAACTCTGCTGCTGTCAAAATTGACTAACTTAAGTCCTTTTACACCAATCCTTTTTGCCAGTTTAATTGGATTTTTTCTCTCGCCCAAAGTTCCTCTGATTGCATCTCAACTGAAGTCCCGGAGAGAAGCTACTGAATGAAAAGGTAGGTCGGCGAAATTAAAGCTAACTGGCTAAGGCTGTCATTTGTCCTTTGTCATTGGTCATTCGTAAGGATTTTAAGCCTACTTAGTTTTTTCACGCTAACTTACTTACCTGCAAAAGTGCGATCGCCTTTTGATTTTCCTCGTGAACGCTTGATTTTTAGGATGGCGATCGCTTCTTGTGTGTAACTTCGATTCTTTTGTTTACCAAAACTGTATTACTGACCCAGGAGTAATTTAGCCTAGTTTATACCTATTCCTCTTGCCATTATTGCTGCTAATAAAGGAATTAGGGTAAAACCAACCAATTCAATTCTAATGAGCCAGATGAGACGATTTAGTTTTAGGAATTCTAGCTTGGGTGCTTGCCCCTGTTGCAGACTTTTCACCCAACCAATGAAAGAAATAGTGGGATAGAGAGATAGCAAACCCACCACGATGAAAACCACAACTTTGGCGTAAAAAACTGGGTTGCTTAAATAGTAATCCGCGCCTTTACCAAAGTAGATAACACGCAAAATGCCTGTGACAAGAACGACAGTTGCTGATATGCCATATACTGCATCAGCTATGACAATCTTCCAAGCCTCATTTAAACTCAATTCTTTTTTTAAATTCAATGCTTCTGATACCAGAGCGCCAAAACACAACATGAAGCTTAAATAATGTAAGTACGCAACTATGGCACTTATCCACATATTATTTTTAGTTTTTGCTAGTTTACCAAAAAGGGGAAAAGAGGAAAGGGTAAGGGGGAAAGGAAAGGATAAAGAACTTTTCCCCACCAGAGACTTCTTGGCATTTGTGGGGAAAGGGGAAAGGAATAAAATTTCCCCTTTCCCTTTATTCCCCTTACCCTTTACCCTTTCCCCTTTCCCCCTTTCCCTTTCTTCATTGTTTTGATATTGCTTTTGATGCGAAAACTTTCATCATCAAGCTCAAATTAGCACTAAGACAACTAGCTAAAAAGTGACCAATAATTCAGATTTTCATTGACTACGAACCCACAATCATTAACAGGGGTTGTTACTGCATTCCCTGGTGATTCCAGCTTTGACTTGCAAAAATTGGCTGGCATCGGCTTTGTTGTGGCTAACGTTAAAAAGTTTGATGGTGTAGATGAATATAGGAATAATCGAGTCTTACTGTAACGGGTTTTTAGAAATTGTACCAGAGAGCGATTATTGGCAGATTGTAGCTATACACATCAATGGCCACGCCTACTGCCCTACTCCTCGGCTTTATCGTTCAGAAAAAGTAGCATTGGCAAAAGCTGCACAAATTTATGATTGGCTAGCTGATCGCGAAGGAGAAATTAGTGATGGGGCTTGTAATTGTTCTGAGTTGAAACTCATCTTATGGAAGCAAATGAAAGTATCTTAATTACCCTTGCGATCCAGAATTTCACTTTACAGCAGTTTTCATGTATTTGAACCACATCCGTCGTAGCGCAAGGCCTTGCGCCCCTACCGTATGGTCTATTTACCTGAAAATTTCTGTAAATTAGTCTGGGTGGCGATTTTCTCCAAAGTAGGGAGTACCTAAAGCTTTAGGAGGTGTAGATTTTCCCACTAATCCCACCAATGCCAATAAAGCGATCACATAAGGTAGCATGACTAAAAATTGGTAAGGGATATTTGCCCCTAATGCCTGAATTCGCAGTTGTAAAGCTTCTGTAGCCCCAAATAGCAAACAAGCCAAAGCACTACCTACAGGATGCCATCTGCCAAAAATTAATGCTGCGATCGCAATAAATCCTTTACCAGCACTCATCCCCTCGGCAAAAAATCTTACCTGTACCAGAGTTAAATAAGCACCTCCTAAACTCGCAAGACAGCCACTAATTACCACTGCGATATAACGGATAGTTTGTACCGAAATTCCAGCCGTGTCAGCAGCTTTCGGAGATTCACCCACTGCCCGCAATGTCAGCCCAAAGCTAGTTTTAAATAAAAGGTATGTAGTTAAAATAACTAAGATAAATAATAAATATACTAAAAAATCTGACTGAAATAGTAGCGGCCCGATTAGGGGAATATTGGCTAAACCAGGAATAATAATTGTCCCAATTCCAGGTAACTGCTGTGTACTACTGCCACTAAACACTAACCGGGCTAAAAACGATGTTAATCCAGCAGCGACGAGATTAATTGCTAGCCCAGATACCAATTGATCGACACGCAAAGTTACACACAAAACAGCATGGAGTAGTCCGACTAATCCCCCAGCAATCAAGGATGCAAGGATACCAAGCCAGGGATTGCCTGTGTAGAAAGTAGCCGCAGCACTGGTAAAAGCGCCTGTAAGCAACATCCCTTCTAAGGCGATATTTAACACGCCCGAACGTTCCGAGTACAATCCTCCAAGGGCTGCAAATGCTAGGGGGACGGCTAGACGTAAGGTAGCTATTAAGTAATCAGAGAAGAAGTTGAGATTATTCATGGAGTTATTTTTTAACGCAGAGGTTCGCAGAGGGAAGCGCAAAGTTTCGCAGAGTTTTCTGAGTTAAACTTTTGCGTCCCTTTGCGTTTTTACTCTTATTTCTCTTTCGACTGCGAAACTGATAGCAATAAATAACACCATAAACCCCTGAATCGCGTAAACCACAGTTACCGGCACGCCTGCACTACGCTGCATTACATTTGCACCACTGCGAAGGGCTGCAAAAAATAAAGAAGTTAAGACTACACCGACAACGCTACCACGACTTAAAAAAGCGATCGCAATGGCATCAAATCCATAACCTGGGGAAACTTGTTCAAATAGCCGATATTTTAACCCCATCACTTCACAACTCCCAGCTAACCCAGCTAAACCACCCGCAGCAGCCATCACCAGCATAATTGTATGTTCAACAGAGATGTGGGCATAACGGGCGGCAATGGGGTTAAATCCCACTGCCGTAATTTGATAACCTAGTGGCGATCGCACTAACAATACCCATAAAATACCTGCGGCAATTAAACCGAATAAAATCCCAGCATGGGCAAGGCTTTGCGGTAAGATAATCGGCAATTGGGCTGTTTTGGCAATTAATGGCGAATAAGGGCTAGGCGCACCTGTTGCCATTAATGGATTTTGGACGAGGTAGCTAACTAAATTCACTGCAATATAGTTGAGCAACAATGTAGTAATTACCTCATTCACTCCGCGTATAGCTTTGAGATAACCAGGAATCCAACCCCAAACTGCACCAAAAAGAAATCCTGCTAAAAGTGCTAAGGGGATATGAATCACCGCAGGTAATCCTTGCACGTATAACCCAATTAAAGTACTTCCCAACGCACCCAGATAAATTTGTCCTTCTCCACCGATATTAAATTGCCCAGCCCGCAATGCCACTAACACGCCTAAACTGGTGAATAATAGCGGTGTCATTTTGGTGAGGGCTCTGTCGATATTAATTCCAGGAGTCATGCAGCAGGCAACTACTGTTTTCTTGTGGACATCTAATCCCGCACAGTGAGTGTAGGTGACTTCCATCTTTCACCTCCATTAATGTTGTCACAGATGGCGTGATGTCCTTTCAAAAATGATTCTGCCTTACGTGTTTCCCACTCAGATTTGGGATATCACATTTCCTTGTGCCACTGGACATCTCGGTCTGTCTCTTGCTCAGGCTCACAGCACTACTGTCATTCCGACCTTTGTACCAACTACTTGAGCAAAATCTATCACATTTTCATTGTTTCTTGTGAGCGCAGCTCATGGAGTCTCTTGCAAAAGTTTTTTGTGATACAATCAGAAATTTACCAATTTGCGATTAAGACTTTAATTAGCAGTGAAATTTTGGAGAGCCAAATGACGAAAGTTACACTCTATATTGCAGCTAGTTTGGATGGTTATATTGCTCGCAGCGATGGCGGAATTGATTGGCTATCAATCCTTGATATAGAGGGAGAAGACTACGGTTATGCTGCTTTCTACGAATCCATTGATGCTATTGTTTTAGGCAGCAATACTTATGAAGTAGGGCTGGGTTTTGATGAATGGCCTTATCCGGGGAAGAAATCATTTGTTTTCACCAAACGCCATCTCCAATCTGACCGCGAGGACGTTGTATTTGTTTCTGATACAGTCAAGAACGCCTTGGCAAATATAGAGGCTCAAGGTTTTAAAAATATCTGGCTAGTTGGTGGCGGAGCATTAATCAATTCATTTCTTCAGCACAGCTTGATTGATGAATATATTATTTCAACTATTCCAACTATCTTAGGTAGCGGTATACAGCTTTTCCCACCGCCAACCCCTGAAGAAAAATTGGAACTGATTAACTCAAAACAATATTCTAGTGGTTTACTGCAATCATATTATAGGCGAAAAGGGAAGCTTTAAAAATCTATAATTCATAATTATGCTTCAAGTGGTGATAAGTCCGATACTCAAAACTTCGGGAAATTTAAACACCACCTGAAGCGTCAATACCGTTATTAAATATCCGGTAAAAAGCCTTGTTAATTACGAATTAAGTTTAAACAACCTCAAGAAGCTTCTGAACAGCTTCGCTAAACTGCTCGTAAGGAGAAACTCCCACAATGGTTTCTGCTAAAATGCCATCTTTGAAAATTAAAACTGCTGGAATACTGCGAAGACCGAATTTTTTGAAAATCGGCTTATTCCTATCAACGTCTACCTTAACAACTTTGGCGCGGCCTTTGTATTCTTCAGCAAGTTGCTCCATCAAAGGACTGACCAACCGACAGGGGCCACACCAAGTAGCAGTAAAATCAACAACAACAACTTTCTCTTCACTTCCATTTAAAACAACATCAAATTCACTTTCTTCAAGATAAGCAACTATCTGAGTATCAGCAGACATTTTTTAATTCCTTACTATTAAACTAAAATTGCAGCAAAAATCTCACTATACAAACTATACCTTCTTCTGTCCGTCAGGTTCACCAGCCACCTGTATTGGCACCCTGCTACTGAGCAAAAGTCAGTAGCAGGGATTTAATAATCTTACATTTGGTGCGTAGGCGTAGCCCGTCGTAGAAATCGCACCTACCAACCTACCTAATCCAAAAACCTCACACCTTCAGGATGTAGAAGATGTAGAAGCATCATCTCGATCAAACAGTTCTAACAACCCAATAGTGCCTACAAAAAAAGTATAAGTGGCATATTGTATTGGCATCTTTTTTCTTGAAGGTGCATAAAAAGCTGCTATAATACCTTCGATAAAATGGCACGTCATGGCAAAACGCTCAATCCAAAAAATTGGATTAAGGCTGCTGGGAATATTACTATTAGTTATTAATGCATAAATATGCCATGATTCTAATCCAATTGCGCTGGATATAAGAACTGTAGATATAATTTTTACCATTGCAAAAAATTTTCTTTTTATAAGTTTTAAGTTCATGCTATTCACAAAACAATCGTTGAAAATTCTCTACAAGACTCGATGAAGTAACAGATAAGTTTATCTGTGATAACCTACGCAAAAAATATCTCAAACTCTTATTTCTCGGTGTTCTCTGTGCCTAGCTTTTCTGTTACTCATGCATAAATCTTATGTGTGTCATCTAAAATTCACCTTAAGTCAACCAATCTTATATCATGATTTACATTTTTGTAAAAGCCCCTCAAAAAATGGACATGGTGTATTAAGTCTGCCATACCCATAAACACTATGAGTAATGAAAATTAATTTACCAGATATTTAAAAAATGATAAAAGTGTGGAATAATGCATTGGTGATAAATTTAGTCGAAATAAGAGTCATAGGTCAAGAGCCAGAATGGGCTAAACGTCTCCGCCTTGACTTCTGAATTCTTCTTCAATCCCCCTCTAGCTATTGATAAAAAATGTAAACCTATGATTGCTCAACATTACAACTCAATTCATGTTGAAAACGACTTGCTTCAACAAATCCAAATTAAAGAAAATCAGTTAAGAATTGCCCAAGAATCTAATATGATCCATGTAGTAGAAGCACTACAGAGTCAGTTATTAAAGTTGCAGTGTCAATTATCAGAGCCGCAAGACGTTGAAGTTCAAGCATTGATGAGTTTGCTAGACGATTAAAATTGTACCTTTTTGTTACAAAGGTTATTTGAAACACAAAAACTCTGTTTATGGAAAGCAGAGCCTAGTTATTATGATGCCTGAAAGTGCGATTTATGTGCTATGGCTCAAAGCTATCTAAGGTATCAGTATCATAAAATCACAATACTTCCGACTTAGATAACATACAGAACTCAGATTTGATTTTACGAAGCTAGGTAGAACTCAAAGAAGCTTTTTTTCTGTTGCCTCTTGCCTACCCACGCCGTGCGAATAGAAATCAAAGCTGAATGCTATATTAGGGTTTTTGCTGCGTAGGTGGTCTTTTAATCTGCTGTACTGACTCAATCTTTAGAACAGGTTTAATTGAGCGCAGTTGCCTTTGCCTAAGAATTTGAATTTCTCTCTCAATCGAATCTTTTCCTTGTCTAAAAAAGTCTTGAGAATTATATGGAACTAAGTCACGGGACAAACTTTGAGCTTGTGCAGGAGTCAAACTAGGAAGGGGTTGTTCAGCATTGGCAGAAGTTTGTACAGCCAGCAAAAAAGCTGCTGAAATCAGCAAGAGTTGGCTTTTTATACATCTGGTTAATATTAGGTTTAACATGATTGATACATCTGTTGTGTAACTGCTACTTCAAACCATCTTCTGTTGGTCTTACTATAAGCAAGCTACACTTATTGGCTTGTTAATTACCTCCCGCAAATGGGTGAATTAATCAGTTAAACTACCCAGCCCTCTCAATATTGACAAATAGTACACTATGTGAGTTTTCTAAGAAGGTAAGACTAAAACTGCACTTAAGCGCTTATGTTATCTCCCCTATTTGATGCTTTTGTAGAGGCAAGCCCCGTCAGTGTAATGATGCGAGTCCTAATGGAAAACATTTTTAATTCCTCGCGAATGAATCAAATATTTGATACATCAAGCGTTCGCCAATACTCTCAAGAGCTACTGTTTTCGACTCAGGTGGATTTGATGAGTCTAGTAGTGTGTGGGATGTATCCCTCGGTTCATGCAGCCTATCAGAAGAAGGCAGTGGAGGTAAGTGTCAGCGCCACAGCGTTATACAACAAACTGCAACGGATTGAACTGCCTGTAAGTCGGGCATTAGTGCATGAGACAGCATCTGACCTCCAGCAGTTGCTGTTGATGTTGAATGTGGAACGCCCCAGTCCTCTAGGAAAACAATATCGGTTGCGGATTGTAGATGGCAGTTGTTTAGCCGGAACCGAACGCAGACTAGCAGCGCTGCGCCCCCATGCAGCCAAACCATTACCCGGAAAAACAATCGCCATTCTCGACCCAGGGACAAAACTGGTGGTTGATGTGATTCCTTGTGAAGACGGTCATTCCCAAGAACGCTCCAAGTTTCATCAGGTTTTGGCACAAGTGCAACCCCAACAGGTATGGATTGCAGACCGTAACTTTTGTACCGCAGGATTTCTCCATACTATTGCCAAACTTGGAGCGTTTTTTGTGATTCGTCAACACGGGGGTTTAGGATACGAGCCTTTTGGTGAGTTACAAGCTGTTGGGTTGTGCCAAACAGGAACTGTGTTTGAACAACAGGTGGAAATTGTCCATGAGGGAGGGACTTTTCGGTGTCGCCGTATCGTAGTTAAGTTGACTCGTCCCACCCGTGACCAAGAGTGGGAAATTGCCATTTTTACCAACTTACCACCCACTGACGCAGACGGCATTCTGGTGGCACAACTCTATCAAGGGCGGTGGAGTGTGGAAACTTTATTCCAAACTGTGACCCAAAACTTTCATGGAGAAATTGAAACCCTAGCTTATCCTAAAGCTGCCTTATTCTCCTACTGCATGGCACTGTCAGCCTACAACCTTTTAGCGACACTTAAAGCAGTTCTTGGCAGTGTACATGGGGTAGACAAAATCGATATTGGGCTATCCGATTTTTACCTAGTAGATGATATCCATTCCATCTATCGGGGCATGATGATTGCTATTCCTCCGGTTCATTGGCAATTCTTTGAGGAGTTTACCAACATTCAGATGGTAGACGTTCTCCAGCATCTAGCAACCAAAGTACATCTCAAATCTTTTCGCAAACACCCCAGAAGTCCCAAAAAGAAACGACCACCACTCTCTGTTGATGGCAAACATTCCCACTGTTCCACTACTCGAAAGCTCAAGCAATACAAAGCAGCTCTTGATGCTATCCCGTGAAGCAATTTCATAAAATATGTTATTTGTCAATATTGAGAGGGCTGGTTAAACTACCTTATTAAATATCTGGAACTAGCTGATATAAGAATATACTTTAATTTTTATTCGCGCAGCGTGGTGTAGCTATACTTACTTGCGTGGCTAGGTAAGAGGCAATAGGAAAGAAGGCTTTTTGAGTTGTACGGAGTTTTTTCAAAAATCAAATATGAGTTCTATATCATCCAAGGTACTAAATAGGAAACAGTTCTGTTAGGTTGGGTCGCACTCTTGGGAATAATACTACTTGGGGGATAGTCTCAATATACCTCAGTGAGAGTACTGTATTATATACTTCTTTTCTGTAACAGCTAATACTAAATCATGAAATTGTATTTTATACAGGTATTGTTGGTCAAATTTAGACAATTATCAACTGAGATATTGGCTGGAACATAGTTATTCTAGGTTTTGTGCTTGCTAATCGTTAAATTATATAAATATAATTTACACTAAAACATATCAGTATTTTAACTGTTGTCTTACCTGTTAATACTTACTTAATATGTAGCACAATCTTTTTAATTATCTTAGCCATTGTGAAATCTCTTCTACAGACTTACTTAGAACAAGAAATTTGGATATTAGTACGAGAGAAGTGGTATTTCGCCACAATTATTGGAGTTTGGGATGATTTGTTGTGGTTTAAACATAGAACTTACAACAAAGATACAGAAGAGGATACTCTCTGGGAAATGGTTGTAAAAATAAGTGAAGTAGTTGCTATTGATAAAGTTAGGTCTGTTATTAGTAGAAAACCAGACGTGCTGATTTCACGGCTACTAGAAACTGAGCAAGGTACAAACGATCATCATCAAGATCATGAACATTAATTAGCTTAATAGTAAAAATACTTGCTTGTCTCCTAACATTAACTGATAAAACTTGAGACAAGCGGTATAAATAAGTAAGCTAAGAGAATAAAGATATTCGCACAACGGATCTTTAATAATAATCTGATAGACTATCTTAAATTTGAAATTATAAAAGCTGGTAGCTCAGGGCTGATAACTAAATATGAGTGAAGCCTTATTCTGTATCGAAAATCTGCGAGTTGCCTATCCTCAACGGAGTGGAGAAGAGGCAAGCTGGGCGGTTGATGATGTATCTTTCACCTTGCAACCAGGTGAAAGAATGGGATTGGTAGGAGAGTCAGGTTGTGGTAAGTCAACTATCGGGCGGGCAGTAATGCGTTTACTACCAGCCTCTAGTTGTGTTGAAGGAAAGGTGACATTTCAAGGACAGTCGGTGCTTGACTTGATGCCTAACCAGTTGCGGAAATTTCGAGGAGAGGCGATCGCATTAATTTTTCAAGATCCTATGACACGCCTCGATCCGTTGATGACGATTGGTAAACATTGTATCGAAACCCTTCAGGCGCACTCACCAGAATTATCAACGCGGGAAGCCAAAGAAAAAGCACTTGCTACTTTGGCGAAGGTGAATATCCCCGCTAGTCGCTGGAATCAGTATCCCCACGAATTTAGCGGTGGAATGCGCCAACGGGTAGCGATCGCTTTAGCTTTACTCCTCAACCCCAAGTTAATTGTTGCCGATGAACCCACCACCAGTTTAGATGTCACCGTCTCCGCGCAGATATTGAAAGAATTAACTCGCCTGTGCGGTGAAGAAAACATGGGATTGTTGCTGATTTCTCACGATTTAGCAATGGTGGCTGAGTATTGCGATCGCATTGGCGTGATGTACCAGGGCAAAATGGTCGAAATGGGTTCTACAGAAACCGTCTTTAGACAACCTCAACATGAATACACGCGATCGCTCTTAAAAGCAGCTTTACACATTCAAGCAGTAAACGATGATGGAGAATTGATAATTGCCAACGACTCAGAAAAGCAATTACCGATTATTAATAAGCAATCTCCAATTTTGAGTATTACAGAACTCAAGCAATACTACACCATAGAACCTAACTTTATCGAACGACTGTTTAACACACAAGCGCAGACAATTAAAGCAGTAGATGGTATCAATCTGGATATTTATCCAGGAGAAATTCTCGGCTTAGTCGGTGAATCAGGTTGCGGTAAAAGCACACTATCACGAACAATCCTGCAATTAATTCGTCCCACCAGTGGCAAAGTTAAATTTTTAGGACAAGATTTAACTACACTGTCACCTCAAGAAATTCGCTCCTCACGGCGACAAATCCAAATGGTTTTTCAAGATCCCCATGCTTGTCTCAATCCAGCGATGACTGTGGGACAAAGTATCGCCGATCCTTTATTTATCCACAATTTAGCCAATCCTGTTAAGGCAAAAGAACAGGTTTTGTGGATGCTAGAGAAAGTTGGGTTAACACCCTCAGAAGTATATTATGAGCGTTATCCATCAGATTTATCTGGGGGACAACAGCAAAGAGTTGCGATCGCTCGTGCTTTGATTACTCATCCTAAACTTTTGATTTGCGATGAACCTGTGAGTATGTTAGACGCTAGCGTGCAGTCGCAAGTCCTAGATTTGATGTTGCAATTAAAGGAAGAATTTGAGTTAACTTATCTATTCATCACTCACGATCTCTGGTTAGCTAGATTTTTGTGCGATCGTATTGCCGTGATGAATGGTGGCAAAATTGTCGAACTCGGTCTGACAAAAACTATTTTTGCCAATCCTCAGCACCCTTATACCAAAACACTACTAGCTGCTGCACCTTTACTAGCACGCGCCTAACTCAACAAAGTGAGGAGTTATGAATTACTAACTCCCCACTACTAACTAATGTACAGACGCGATTAATCGCATCTCTCCTAACTCTCTTCACTACCCTTAAGTAATTTAGTTGCTTCTCCACTCGAAGCATATAGTTCAACGAATCTTTTAAATAGCAATGCAGTCTCGTGATTTGAAGCTCTGTTTAAGTGGAATAAACGCTCTATATTTTTATCCGCTAAAGCTCTTAAATAGGGCAAATCTTCAAATAGTGTCAAACAAGAAGCAAAATGCAATATTATTTGTAATAATGGCTTTGGCCACTCTAGGTCACTATATATATCTATAAAGAACTGATGTTCTGAGTCATTTAACGGAAAAGCATTAAATAAAACAATTATCCTTTTGTTATTGTAAACTGGAATACTCAATTCAACGGTATATGGAGTATGTAATATTAAATCTACCTCCACAATCGGTTGTCGCCAAATTCTCAAAGGATTCGCTGGCGAGTCTAATATTGTTTGGAATTTGATTATTCCACCAGTACTAGTGGGCTGAAAGTGGCTAATTTGAAAAATTTTCAGGTTATTAAGGCTAAAATTATGAACTGTTTCTAAATGCTTTAAGTTCAATAAATGATAAATTTGACAAAGATAAGGAAACGGTAAAATATACTCCTGGCTAATCATGTGGAGCTTTTTTACTTGAAGCTTATTAGCTTGAGTACGAGCAAGATATTCTTGATATTGGCTGGGGCCTAAATCGTTACTATTAAAGCTTTCGTTAGGTTTGAGATATAGCCAACTCACAAAGAAGAAAGAAGCTGTAAATAGCTGGAATATTTCTATATAAGATAAATAGCCATCAGCAAATGCAGCTATACTTCTATCGGTTATTCCAAAAAGCCAAGATGGAATACCAAATATCCAGATATTACTTTTAATTTGATCTATAAAAAGTGCTATTTCAACATTGTTTGAGGCATTTTTATCTTGATTTACACTTAATTTATCATTATTTTTTAGACAATTAGTAAACATAATATTTCTAATTCACTAATCCTATTAATCTATAAAATCTATTTATATTAATCTTAAATACCAATCCACAACTGTAACCTCTATCTTTAGCTGTATATACAAGTTGTATTTATTTCTATCCATTTAAAAGAAGTTCTTATGAGTATGGTTAAAAAATTCAATCCCTGATTAGATGTAATACTAAATTCTACGTATATCCAAATTCCTTGTAATTCTTGCTCTTAAAGGATTTAATGTTATATTCTCGAATTTATGTATAAATTACAAGGAACAAATTTGCCAAAATCTTTCTACTAGCTGAGTACAAAAAATTAAATTATCTCACTTTTTCAAAAGTGGTATACATATAGATAAAAAAGTTTTCTTTTCCTGACATGAGAAACTTATTTAAGTAGTGCAGTGTGAAAAATCAAACTATTTAAATATAAATAAATAGGATTTCTCTATCTATTGAGGTAATAGATATATAGGTACTTGTATATCAAAAGAGTATTTCTAACTAGTCAGAAATACAAAATTATGTAAAAGCCCAGAACTGTGGATCTGACTTTTCACAGTATCTGGAAAAGGTCATTTTCAGGGTTTCCCAAGCCTGATCTTTCCATAGGCTGATTATCAATAGCTCTGAGTTAATGATAATCAAGCTATGGAGAAAGTTACGCTTTTCCGGAGCTTGAGGACTTAGTATGAGAAGTTAGAATGGCAGAACCCCCGTGATATAAAGCAATACAGTTCAGTTAAGCATCTCTTTCTTCTCTCTGCGTTCTCTGCGCCAACTCTTGGAGACGCTGCGCGTTGGCGGAAGCCTCCCGTAGAGAAGGCGGTTCATTAAAAAAACGACTTTGGTAACAGAGTTTTAGCTTTAGCTGAACCGTATTGTGATATAAATCTCTCGCTGTTATGAAAAACCAGGGGATTTAAATGTAACTAGTAGTTAATATTTGATATTGAATTGGGCAAAATGATCTCAGGCTCTTTCTATGACAGTAGATTTGGCCAAATTTCCTAATGATAACTTCTTCACCAGTAAATTCATAGATATGAGCAACTATACCAAAACAAAATCTCTGCATGGCTATCGCATTTTCAAGTTACTTTACTCTGGTAATAGACAAATCAATTCATTGTATTGAGATATGGATAGCTTTCTCAATGTCTAAAACTAAAAAATAGTGAATCAATATGTCTATTGAAGAGTTAAATCAAGAGTTAACCAGATTACGTCAATGCCTTCAGCAACTAACAATAGATAATGCTGAACTAAGTCAGGCAGTTCTAGAATATACTACTCAATTACAGCAACATAAGAGCGAACAGCAAGCTGCACTAGATGAGCGCCAACGGATAGAAGAAGAACTGCAAACTGCTCAACAGTTTCTGTATTCTGTGATTCAAACCATGCCTGTAGCAGTTTTTGTCAAAGATGCGGCTGATCTGCGAATTGTCTTATGTAATCAAGCCGCAGAAAAGTTAGCTGGTGTCAGTGCTGATGAAATTTTAGGCAAGAACGACTACGATCTATTTCCTAAAGAAGAGGCCGATTTTTTTACCCAGCGAGATCACGAAGCACTTAATAGCAAAACATTATTAGAGATTCCTGAAGAAAGAATTCGGAAAAAAAGCGGCGAAACCCGTATTTTACAGATTAAAAAAGCTCCGATTCTTGATTCTCAAGGTCAGCCCAAATATTTACTAGTGGTTCGAGACGACATTACAGAAGATAAACAAGCAGAAGCTCAACTCAAACAGCAAGCAATAGAACTAGAGCAAACTCTCAAAGAATTACAAAGTACTCAAGCTCAACTTATTCAAAGTGAGAAAATGTCGTCTCTGGGTCAATTAGTTGCTGGAGTTGCCCATGAAATCAATAATCCAGTAAATTTTATCTCTGGCAATTTAACTTACGCTAACCAATATATCCAACAACTACTGAATCTACTTCATCTTTACCGCATAAACTATCCCAATCCTGCTCTTGAAATTCAAACGACAATTCAGGAGATGGAATTAGATTTTTTAGTCGAAGATTTGCTAAAATTACTCTCTTCAATGGAAGTCGGTGCTGAACGCATACAGCAAATTGTGCTTTCTCTTCGTACCTTTTCGCGGCTAGATGAAGCCGAGTTAAAAGCAGTGGATATTCATCAGGGTATTGACAGTACACTGAGTATTTTGGAGCATCGTTTGAAAACTAGAGCCAATCATGTCCAAATTCAGGTTCTTAAAGATTATGACAATTTACCTTTAGTTGAGTGCTATGCTGGTCAGCTAAATCAAGTATTTATGAATATTTTGTCCAATGCAATCGATGCTTTAGAAGAGCCATTAATTCAAGGTAAACTCTCGCATAACCAGCCACAAATTCGCATTTGTACTCAACAACTGAATCCTCAAAAAATAGTTATTCGGATCATCGATAATGGCCCTGGTATTCCCGAACAAGTTAGACAAAAGTTATTTGATCCTTTTTTTACTACCAAAGATGTGGGGAAAGGTACTGGTTTAGGTTTATCAATTAGCTATCAGATTATTACCGAGCGGCATGGTGGTTCGTTAGAGTGTGTTTCTTCTCTTGAAGGGGGAGCAGAACTTATTATTACAATTCCAGTTGCACAACTCAAACAGTAATTTGGATTCAAAATGTGTGATTGCAAGTATCTGGAACATAGCGAGGATTTGGGGATTGGTCAACTACAATTCACAATTTGCAATGACGCTCTTTCGTCGCTAACGCTGCGAAGATCGGAATTCGCAGTTAAAAAAATATAAAGTTGATAAATCGAATCAGGAATAAGAATTTATTCTGTATTATTTAGAACCAAGTTTCGTCTGAGAACCTTTAATGCTCAGTATCTGAAAAATAAAATAATTTATCTATTTGATGCCAAGCTATCTGGGGGAATATAACGAAACTCCAGTGAGGTTAAGCAATGGTTAATCAGACATATACAGTTGATGTCTTAGTTGTCGGTGGAGGAACCGGGGGCACTGCGGCTGCTATCCAAGCGGCACGACGGGGAGCCAAAACGATGTTGGTGAGTGAATTTCCTTGGTTGGGGGGAATGCTAACTTCGGCTGGGGTGTCTGCACCCGATGGCAACGAATTAGAAGCCTTTCAAACGGGTTTATGGGGTGCGTTTTTGCAGGAATTGCGGCAACGGCAGCCCGGAGGATTAGATAACAGCTGGGTAAGCTTTTTTAGTTACGATCCTCAAATTGGGGCAGAAATTTTTGCAGATTGGGTGCAGGAATTACCAAATCTGCACTGGATTTCTGGACAAGTACCAATAGAGGTATTTCGCCAAGGTGATTCTATTACTGGTGTGCGCTTTGCTGATTTTGCTGTCACAGCCAAAATTATTCTCGACGGTACAGAATTAGGAGATTTATTAGCTTTAGCTGAGATACCTTACCGTTGGGGCTGGGAATTGCAATCTGAGTGGGGAGAACCAAGTGCTCCAGTGGTTTTTAACTCTTTCACCCAGAAATATCCTGTGCAAGCGCCCACTTATGTAGTGATTATGCAAGACTTTGGTGATGCTATGTCTACGACATTCACTGAGCGATCGCATAGCGTTTCGCAGAAAAGTCGAAGTGCGGGCGTAGCTGCGGCACCAGAAATTCCGGCTGCCCCTAACTATAATCCATCCCAGTTTACAGATGCTTGGGATGGCTATGGAGCAGAGACATTTTTGAATTATGGACGTTTGCCTGGTAATCGATTCATGATTAATTGGCCAATCTGTGGCAATGACTACGGCCAAGGAGTAGGGCGGCTGATAGAGTCAGATGTGTCCAGAGGTGAATTCATCCAAGAATCTCGCTGGCATAGCCAAAATTTTGCCCATTTTATCCAAAATCAGCTTGGTCGTCGCTATGGTTTAGCAGAAAAAGTATTTCCTCACGCCCCTACAGCTTTTGCACTGCATCCGTATTACCGGGAAAGCCGCCGCTTATTGGGACTAACTACTGTCCGAGAACAGGATATTTTGCCGATCGCCGGCGGAAGAGTTGCATCTATATTTAATGATGCGTTCGCCCCTGGCGTTTGCGAAGCGATCGCAGTTGGTAACTACGCCAATGACCATCATTATCCTGGTGTTCAATTCCCACTGCAACCAAAATCTATCCGTTGGGGCGGGCGTTGGACTGGGACACCCTTTACAATTCCCTACAGTTCCCTAATTCCAGCCACAACAGATGGTTTCTTGGTTTGTGAAAAGAACATTTCTGTCTCTCACATTGCCAATGGCGCTACCAGATTACAACCTGTGGTTATGGGCATCGGTCAAGCAGCAGGTATGGCGGCGGCGATGTGTGTTGAGTTAAACTGTCAGCCGAGGCATTTACCTGTTAGATCACTGCAAACAGCTTTATTAGAGGATAATCGTTCAAAAACAGCAATTATTCCTTTATTTAATCTTCCACCCAATCGTTCGGATTGGCTGGACTGGCAACTGTATTACTTAAATAACCCACAAGCCTATCCAGATAGTGGTTATTGCCCTTGCCCATCGGAGAATGAGTACCCTGACTCTGCTTTTGAAAAGGCATTAATTCGGGAAAGTAACTGTTTCAAAGGCATTTTCTCCCGCTTGGAACAGCAGGAATACAGATTTGCTGTCACAGCGCCAGCCGCATATCAAGGGCAAAATTGGCAGCTTGTAACTTTGCGATCGCATATCGACGAGCAATTACGCACTTACCCTCACGAACAATTAGTTACATTGTGGGGTCGCCAGAACCACTTTGGTAATTGGTTATTAGTCGAACAATTAAACGGAGGATAAGAAGAGTTTATTTTCAGTAAAACAGAATACTTTTTGATTAATTGTCCGGATATTAATCAAAAAGCTAAGTATCAGTGAAGTGGAGAGTTCCAAAATAGACATTTGCTATGCGTGCTGCCATTTCACTTTTAGTATCGAGTCTGGTGTTCGGCCCCTTAGCTTCTAACTGCCAAGCAATGGTCAATCACTTATCAACTGGGCTACTTTCCACGCCTACTTCGGAACAGTGGCTCTCGGCAGCATCTGAACAAAATCCAGATGATGCGCCACGTCATCGCGGTAGTGGGCGTAGGGAAGTGACACAAAAATTCGGAAATACCTATGTTGTGGTTTAACCACCGTAGGATAATGCCTGTTCTTCAAAAAGAACCAAAACTAAAGTTCCAGAAAACACGATGTTGTGCCAACATATTTGACACAGCTTTTGTGACAGAGATATATACAGTTGACACACGAAAATCTTCAGCGATCGCTTAGTATTTCAACTGCAAGCTTTGTATATCATTAGTTGGTCTTTTAATCCTGGCGATCAAAACGCAAATAAAATTAAGTGTCTTGATCAGCAGCATTAACAACTCCCAAAAGCTACATAACTGTTGCTTATATTCGGTGGGAAGCTCTGCGTCTCAATCCTTAACGGCTCTAGAAATAGATGTTATTTAGACTATCAGTTAATCTAAAGCACGTCTAATTCAAACATTTTGCTTGTTAAGGAAATAGTCTTAAGGCAACTTCATTCACTTTATTCCCCAATATCTTTTCTTCTCATACATTGAGTAGCTGGTTTCTATATGAGCAACTAATGGATCTTCACTTCGACGCGTGTTTAGCGTCCTTTACCTAAGCATAAAATCCCTTTCGTTCCATTTGAGCTTATCTAGGACACAGATTCGCACAAGTAGTATAGATTTATTGCACTTGGCAACAAATATTACTATTTATGAGCTACTCTTGCACTCTGGTTCGTTCTCCTCGTAGATGGTGTTCAACGAAATAAATATTAAGAAGAATTTGCTAGAGAATCTCACTCATTTTAATTATTCTACACCTAATGACAGATGCAAAATTTTGCATCTGTCCTTTTTAGGTAAAGTTTCCTTAAAGAAAAGGCAATGAAAAGGTATTGTTTCAAGCTGGCTTATGAGCAATGAAATACTTACTCATAAAATGGGTTTGTATCTCAATATTCTCAAAGCCTACTCTCTGTAAACGCTCTAGCAAGTTATCAGTGGTGTAATGCCTGTAATAGGGTTCATGGAAAGTTTCCGGAAAAGAATCCATTATATGTTCCAACTCAGGTGAATCACTCAACTGAATTGAGTCACAGATAATAAAGACTCCTCCTGGTTTTGTCACCCGGAAGCATTGCTCAATAACTGTCTGACGTACAGATGCTGGTAACTCATGAAAGAGAAAAACAGAAGTTACAGCATGAAAATAATCATCTACATAAGGTAACTCTTCGGCATTCCCTTGCAAAAGTTGCGGCAGTTCTCCTGGGATTTGCGATAGTAGTTCATTTGCTTTCCGCAAATAGGCTGGTGACAAATCTGTGCCAAACAGAGATGCTTGAGACAAGGCTGCCCGAATTAACTTTAAAGTCCGCCCAGTTCCACAAGCTACATCCAAAATACGGACTTGCTTTGGTGTAACCGAATCAGAAGCTTTCAGCCCTTGCTTGAGAGGAGCGAGAATTCGCCGCCGCATCGCATCAGCTGCCCCACCAAAAAGAATTTCTACTTGTAAGTCATATAAATTGGCTGACAAGTCACTCAAGTAGCCATCGCTTTGGTGATGGAAGTTCTGCACGTAGTAGCTGGGATAACCATCAGTGTCAATTTCGGGCGAAAAATCTTGATAATTTTGTTGTTTAACCCGCTCCCAGATTTGAGGAGAATCTAGCCACATCAGAGGATAGTAGGAAAAAAAGTCTTGCCAGGGGTTATCAAACAATAAACTTTCGGGGTAGACACCTTTTTGGGCATCTTGCCAGTCTGTTTCGAGCAGCTGGTTCAATCTCTGTTGAAGCTGGACTAAAAGCTCATTTGGGATGGGTTTGGTCTTTTGTTCAAGTGTCGGATACACCAGGTTCCTCAACTGTGAACTTAATATCTTGTGAGCCAGACCAAAGTAATTTTTACCCTGCTGAAAGGTCTGATAAGTCAGCTTAGTTAAACTCTCAGGCATAAAAATAGCTTCAGTTTTGATTACTTTTATGTAAATAATTGTAACGAAAAAATTATCTACTGTTGGAAAAGTAAAAGCTCCCAGGGAAGACAACTTGAAGCCAGATGATTTTAGCCATTAGAGATAGATTGAGCAAGATTTTTCCAGCTTTGGGGATAAATGGCTAATATTGTCAGCAAAGCAAAACATAAACTTATGTAAAAAGTAGCTTATGTTACAGAATTTTTGCTATATTAGTCTTGTAGGAAAACAAAAATTATATATTCACAAAATAGAGAGGACTATGATTATGTCTATCGCAGATAAATCTCGTGCGTTGATGGTGCGTGAACATCAGCAAGTCAAGAATCGCCAACAATCAATGCTGATGCGGGCTGCACAAGAACTTGGTCTTCCTGAAGAAGTATCTCACTACTGGAACCCAATTCAAGGGAAGGTAGATGCTAGTAGTCGGATGATTTATGGCCCCAGCCACGCTTCCATGAGTTAAGTTTCAAGAGTTTGAAGCTAGATTTTTTGAGTGAATATCTCAACTGGCAACTCTGGAAAAAAAAGCCACCCTCTACTCTAGGGTGGCTAAACTTATTAATTTTAGTTAGATACGATTCTTAATTTAATTAATTAAGCATCGTAGTAGAGGTAAAACTCATAGGGATGAGGACGTAGCTGTAACTGCTTGGCTTCGTTAAGCTTGTAGTCAATCCAATTTTCGATAAAGTCTTCCGTGAATACGCCTGATTCTGTCAAGAAAGCGTGATCGTTTTCTAGTGCTTGCAATGCCAGTTCTAAAGAACTTGGAGTTGAGGGAACCTTTGCAAGCTCTTCTGGAGAGAGTTCATAGATATTCTTATCTAAGGGTTCACCAGGATGTATTTTGTTCTTGATGCCATCGATACCAGCACAAAGCATTGCAGCAAATGCCAAGTAGGGGTTAGATGTAGCATCTGGACAACGGAATTCTAAACGCTTGGCTTTGGGGTTCTTACCAGATAGAGGAATACGGATAGAAGCAGAACGGTTCCCTTCGGAATAAGCCAAGTTTACAGGAGCTTCATAACCAGGTACTAGGCGCTTGTATGAGTTGGTGCTGGGGTTGGTAATTGCTAACAGTGCTGGTGCGTGTTTGAGAAGACCACCAATGTAGTACAACGCCATATCACTCAAACCAGCATACTTATCACCTGCAAACAGAGGTTGGCCGTCCCTCCAGATGGACTGGTGACAGTGCATTCCTGAACCGTTATCGCCAAAAATCGGTTTTGGCATGAAGGTGACAGTTTTACCATATTTATTGGCAACGTTCTTGATGACATATTTGTAAGTCATCAACCAGTCAGCCGCTTCGATCAACTTCCCAAACTTGAAACCTAGTTCGCACTGACCACCAGTAGCAACTTCGTGGTGATGCTTTTCAATGGGCACACCTAATTCTGCCATTGTCAACAGCATCTCTGTACGGATGTCTTGGAAAGAATCCGTCGGTGCGACTGGGAAGTAACCTTCTTTGAAGCGTGGTTTATAACCCAAGTTGGGTTTTTCATCTGTACCGGCTTTACCAGAATTCCAAGCACCTTCTTCGGAGTCTAAGAAGTAATAGCCTTCGTTAGCAGTTTGGGCAAACCTAGCACTATCAAAGATAAAGAACTCAGCTTCAGGCCCAAAGAAGGCTGTATCACCAATGCCACTGGCAACCAGGTAATCTATTGCTTTTTGGGCAATAACCCGTGGGCAACGGTTGTATGGTTCGCCCGTGCGGGGGTCTTTAATACTACAAATTATACTTAGTGTTGGCACTTCCATGAATGGATCGATCCAAGCAGTGTTGGGGTCGAGTACCATCGTCATGTCCGATTCGTTGATCGCTTTCCAACCCCTGATGCTGGAACCGTCAAATGGTACGCCATCAGTGAACGCAGTCTCATCGATTTGGTTTTGGTACAGTGTGAGGTGCTGCCAAGTCCCTACTGTGTCGATGAATTTGAGATCAATCAGTTGAATTTTTTCATCTTGAATTCTCTTCAAGAGTTCTTGTGGTGTAGTCATTGTTACTCCTTCTCTACCAATTTCCTAAAGTCAACCAGAATCTTACATTGCATCCTAACCCTGCTGATCTCAATCAGACCGTGACACACCAGAAATATCTTAAATAGTAGACATTAGCTGATTTTGTAGTTTATGTTACAGATATCTGGATTATCAGGTTATATTAACCTTTCAGCGCTCATCTGTACAAAACTGGAAAGTTCATCATATAGGGGTCAACTTTGGCATAGAATCCTTAAATAGTGGATAGATTGTTTTTGTGCCGAATCTATTTTAAATAGCACAAAAATTTACTGGTGCGTGAGTGCAGCCAAATAAATATCAAACCATAAATAGCAAGGATTGGGAGAAAAAAGAATGCGCGATGCGGTAACAAGTTTAATTAAGAATTATGACTTAGCTGGTCGGTATTTTGACCGGAATGCGATCGATAGCCTAAAGTCTTACTTTGACAGTGGTACAGTCCGAGTCCAAGCGGCGGCGGCGATAAATTCTAATGCGGCTGCACTTGTCAAGCAGGCGGGTTTGAAGTTATATGAAGAACTGCCAGAATTGATTCGCCCCGGTGGAAATTCCTATACAACTCGTCGTTATGCAGCTTGTCTGCGCGACCTTGATTACTACTTGCGCTACGCTACCTATGCGCTAGTTGCTGGGAACACAAATGTATTGGATGAACGAGTGCTGCAAGGGCTACGGGAAACTTACAATTCTCTAGGCGTGCCTATTGGGCCTACGGTTCGTGGTATCCAGATTCTCAAGGATCTGATTAAGGAGCAAGTAGCAGCAGCAGGTGTGGTTAATACTGCTTTTGTGGATGAACCATTTGATCACATCACACGCGAGTTGAGCGAACAGGATATTTAGCATCTAGGTTTGGTGACTAAAAATCGCGGAACTATACAAAGAAAGTTCGCGTAAGCATACTTTACAGACATCGCACTTTGGCTTGATTGGCAAGGTGCGTTTACTTTTCTTAAAGCAAACTAAAGAAAAATATCCCGATGTCCATGAAGGTATATTTTCCGAACGCTTTGGTCAGCTAATTCTTAATAGTATAGGAATAAACCTAATTGTCTTTGACGAGCAACTAGAAAGGATTATCAGATGGATAACAGGACTTACGCAACTGGCACAGTGCGATCGCAATTTTATAGTATTTACGTACTATGTCAAAGTGGCGTACCTAGAGGACATTGCTGAAATTAATAACAGTAATTAGCTGTGTTAAGTATTTTTCAAATCATGAGAAAATGAGTTGAGTATTCAGAAAATAAATCTTGTAGTTTATGAGATTTACAAAACTTAACTATTGCCAGTACTTGTTAAGTAGTCAGATTAATTATACTCTGACAAATTTGGCAGAGCATTTAGAGCAGATTAGTCATGATAAAATTAACCGTTATCTTAAGAATGAAAAGTTAACACCACGTTTACTTTGGGATAATGTTAAAGATATCTTACAAGTGAGTGATAGCGCATATCTAGTTTTTGATGACACAGTACTTGATAAACGATACGCCACAGAAATAGAGACCAGTAAAAGGCAGTATAGTGGCAACCAACATGGTGTAATCCAAGGTATTGGGCTAATAAATTGTATATATGTCAATCATGAAATCGGAAAGTTTTGGATAGTTGATTATCGGATTTATGACCCAGATAGAGATGGAAAAAAAAAGATAGATCATGTTACAGAGATGCTGCAAAACCTTATATATCATAAGGCTTTACCGTTCCAAGCTGTCTTAATGGATACTTGGTATGCAACAAATAAATTGATGTTATATATTGATGGATTAGGAAAATATTATTATTGTCCTCTGAAACGTAATAGACTTGTTGATGATACGGCAGGTCAAAAAAATTATCAAAGAATTGAATTGTTATCTTGGGATAGCCAGGAGTTAAAATCAGGTAAAATAATTAAAATAAAAAAGTTTCCCCAAGCTACAAAAGTGAATCTCTTCCGGGTAACTGTCTCGACCGACAGAACGGATTTTATCGCTACTAACGATTTATCTCAAGATTCTACGGACGTTGTACAAAAAGTGTGTAAGGTTCGATGGAAGGTTGAGGAGTTTCATAGAGAATTAAAACAAGTAACTGGTATTGAATCGTGTCAATGTCGCAAGGGACGTATTCAAAGAAACCATATTGCCTGTGCTATTTTAGTCTGGCTTCGACTCAAACATTTAGCTTATCAAAGCTACCAAACAATTTATCAAATTAAACATGGATTATTATCCAATTATTTAGTTCAGCAACTAAAACGCCCGAATGTTCCCATGTTTATTGTCTAG

Protein sequences of DBSCAN-SWA_5

>NZ_CP046703|3668351:3726015|3697063_3698536_-|WP_159402428.1|transposase|DBSCAN-SWA
MEKNLPLKLDTETLKQLEKEQLVEMLMEQAKAIEQLKSRVIELESVIEKLKVSRDLDSTTSSKPPSADILKKTEKKLEDEAGESETPKRKPGGQPGHRGKTRKGFGRVDRFEILRPQVCFCCGQKEFSNEPIKIETQQVAQLVERPIEIVEYQRHTCICSECGSKQTADWSPEIVPGQDIGIRLQAFLGWINNYGHLPYEKQQELLWELGEIEIGVGTLVATNERIDGAVAQSIDNLKEWIKQTQPNIHSDETPWVIKGVKEWLWIFANTDFALFHAADTRSRAELEAILGSSYSGVLSSDDFSAYNGYPVKAQQKCQAHLRRHFKKLILIPGLNNKEIGSAFVSLIDEGFKNYALFQQTKNIDEFWSWASEFKIKVESSIHSWIDKAGGEAGKLLRSLRNKAHQWWYFLDHPDIPPDNNLAERTLRLAVTKRKVSGGSRSMKRFQDTANLLTVIQTCRRQGRSVIEFFDQAIKAMVNSSVQTPSLIPLV
>NZ_CP046703|3668351:3726015|3711521_3711815_+|WP_114080534.1|DBSCAN-SWA
MKSLLQTYLEQEIWILVREKWYFATIIGVWDDLLWFKHRTYNKDTEEDTLWEMVVKISEVVAIDKVRSVISRKPDVLISRLLETEQGTNDHHQDHEH
>NZ_CP046703|3668351:3726015|3671750_3673454_-|WP_114081265.1|DBSCAN-SWA
MLDLLIQNGLIFDGLGSPPVRGDIGIQNGRIVTLAPSLTTPAREVVDASGLWVTPGFIDIHTHYDLELEIAPGLSESVRHGVTSVVIGNCSLSVAIAEPQILADIFQRVETLSHRLIAKWLKKSVSWQTPAEYLQHLQQLPLGPNVAPMFGHSALRAYVMGLERSLTVQPTKFELKLMQRIARDAIDAGFIGISIDMFPWHRMSGEWQGCTIPSQHAKFNEYAMLADLCRHSDRVFQVTPNLQRLASFVDILRMGSGIGQKPLRLTVLSALDAVHDRKLWRIFSPLLFIWNRLLNGNVRFQTLTEPFTIYSDGSVTPLFEEFSTGAQLNGCQSREERQQLWASEIFRRQFRQEWLSKRRKSFHRQLDLMEVIHCPEASWQGLSFAQIARQKQQEPVDLFIHALQKYDTDLRWVATGANDRLKPRLAMMQHPHILPGFTDAGAHVRNLGYYDGALSLLKQAVTTKFLSPEAAICRVTGEPAGWFRLNTGVLKVGAKADIVLLDPNALNQPISPQVQISDPVLDGEPRMVKRGSDEIVQRVYINGVQVVCRGKVSDRLGREKLGTVLFP
>NZ_CP046703|3668351:3726015|3687396_3688911_+|WP_114086205.1|DBSCAN-SWA
MHIGFLNPQGNFDSNNSHISKHPDFGGQLIYVKQVAIAIAEKGHKVDILTRQIIDPEWPEFAEAFDTYPGIDNVRIIRLPAGPKEFLPKELLWTHLISDWVPNILKFYQQQGGLPDAMTAHYADGGLCGVLIEEDTGIPFTFTAHSLGAQKMDKLEVTSENLLEIDEQFHFKYRILAERLSMNRSVVNITSTRQERFQQYSHRVYRSAVDVDNDNRFAVIPPGADFSIFGAKARSENEKATEEFIQERLARDIAEARRDLPVIVASSRLELKKNILGLVQAFAISPTLQERANLMLLTGGLDDPLREEASDSIAEEVLAPIREVVKENDLWGKISAFGLSDQSQESLAAAYRFMVKRRSVFALTALYEPFGLAPLEAAVAGLPVVATKNGGPSESLRQGNKEYGILVDPEDPADIARGLERVLCDAQEWDYFAQAGQQRVLKTYSWESTAENYLTLLEQILSLPENRDRAELLPIHPYFRNPESQTDVSLEELSDLYFGTNQKA
>NZ_CP046703|3668351:3726015|3713747_3714692_-|WP_114080532.1|DBSCAN-SWA
MFTNCLKNNDKLSVNQDKNASNNVEIALFIDQIKSNIWIFGIPSWLFGITDRSIAAFADGYLSYIEIFQLFTASFFFVSWLYLKPNESFNSNDLGPSQYQEYLARTQANKLQVKKLHMISQEYILPFPYLCQIYHLLNLKHLETVHNFSLNNLKIFQISHFQPTSTGGIIKFQTILDSPANPLRIWRQPIVEVDLILHTPYTVELSIPVYNNKRIIVLFNAFPLNDSEHQFFIDIYSDLEWPKPLLQIILHFASCLTLFEDLPYLRALADKNIERLFHLNRASNHETALLFKRFVELYASSGEATKLLKGSEES
>NZ_CP046703|3668351:3726015|3719589_3719817_+|WP_041565664.1|DBSCAN-SWA
MRAAISLLVSSLVFGPLASNCQAMVNHLSTGLLSTPTSEQWLSAASEQNPDDAPRHRGSGRREVTQKFGNTYVVV
>NZ_CP046703|3668351:3726015|3707781_3708108_-|WP_114080572.1|DBSCAN-SWA
MNLKLIKRKFFAMVKIISTVLISSAIGLESWHIYALITNSNIPSSLNPIFWIERFAMTCHFIEGIIAAFYAPSRKKMPIQYATYTFFVGTIGLLELFDRDDASTSSTS
>NZ_CP046703|3668351:3726015|3703862_3704126_+|WP_114080574.1|DBSCAN-SWA
MNIGIIESYCNGFLEIVPESDYWQIVAIHINGHAYCPTPRLYRSEKVALAKAAQIYDWLADREGEISDGACNCSELKLILWKQMKVS
>NZ_CP046703|3668351:3726015|3722290_3723712_-|WP_114080529.1|DBSCAN-SWA
MTTPQELLKRIQDEKIQLIDLKFIDTVGTWQHLTLYQNQIDETAFTDGVPFDGSSIRGWKAINESDMTMVLDPNTAWIDPFMEVPTLSIICSIKDPRTGEPYNRCPRVIAQKAIDYLVASGIGDTAFFGPEAEFFIFDSARFAQTANEGYYFLDSEEGAWNSGKAGTDEKPNLGYKPRFKEGYFPVAPTDSFQDIRTEMLLTMAELGVPIEKHHHEVATGGQCELGFKFGKLIEAADWLMTYKYVIKNVANKYGKTVTFMPKPIFGDNGSGMHCHQSIWRDGQPLFAGDKYAGLSDMALYYIGGLLKHAPALLAITNPSTNSYKRLVPGYEAPVNLAYSEGNRSASIRIPLSGKNPKAKRLEFRCPDATSNPYLAFAAMLCAGIDGIKNKIHPGEPLDKNIYELSPEELAKVPSTPSSLELALQALENDHAFLTESGVFTEDFIENWIDYKLNEAKQLQLRPHPYEFYLYYDA
>NZ_CP046703|3668351:3726015|3724673_3724934_+|WP_114080528.1|DBSCAN-SWA
MRLLFLKQTKEKYPDVHEGIFSERFGQLILNSIGINLIVFDEQLERIIRWITGLTQLAQCDRNFIVFTYYVKVAYLEDIAEINNSN
>NZ_CP046703|3668351:3726015|3717622_3719482_+|WP_114080530.1|DBSCAN-SWA
MVNQTYTVDVLVVGGGTGGTAAAIQAARRGAKTMLVSEFPWLGGMLTSAGVSAPDGNELEAFQTGLWGAFLQELRQRQPGGLDNSWVSFFSYDPQIGAEIFADWVQELPNLHWISGQVPIEVFRQGDSITGVRFADFAVTAKIILDGTELGDLLALAEIPYRWGWELQSEWGEPSAPVVFNSFTQKYPVQAPTYVVIMQDFGDAMSTTFTERSHSVSQKSRSAGVAAAPEIPAAPNYNPSQFTDAWDGYGAETFLNYGRLPGNRFMINWPICGNDYGQGVGRLIESDVSRGEFIQESRWHSQNFAHFIQNQLGRRYGLAEKVFPHAPTAFALHPYYRESRRLLGLTTVREQDILPIAGGRVASIFNDAFAPGVCEAIAVGNYANDHHYPGVQFPLQPKSIRWGGRWTGTPFTIPYSSLIPATTDGFLVCEKNISVSHIANGATRLQPVVMGIGQAAGMAAAMCVELNCQPRHLPVRSLQTALLEDNRSKTAIIPLFNLPPNRSDWLDWQLYYLNNPQAYPDSGYCPCPSENEYPDSAFEKALIRESNCFKGIFSRLEQQEYRFAVTAPAAYQGQNWQLVTLRSHIDEQLRTYPHEQLVTLWGRQNHFGNWLLVEQLNGG
>NZ_CP046703|3668351:3726015|3676837_3678121_-|WP_114086200.1|DBSCAN-SWA
MGRSNYQPSKNISFHRRLKATIIVLFVWGGVSLLHWLPETQWLMLGLTAILTVQTLRMLLAKPVAAVMESEIYLPPVSILVPAKNESPVLANLVYSLCQLNYPSDRLDIWVVDDGSTDETPQVLRELQTQFPSLQVHRRESKGGKSGALNAVFPFTQGEIILVCDADAQLPANFLQRTVPLFQKQAIGAVQVRKAISNANTNFLTRCQQMEMCCDSFLQTHRIAIGGMSELRGNGMLVRRELLEKCQGWNENTVTDDLDLCFKLYLAGAEIEFVTVPSIQEEGVTTWEKLWNQRCRWAEGGYQRYLDYFPQILTLGWAKEIDLLLFFLLQFLLPIGLIPDLVWTILYSHHPVLFPLQTLLSIILTIAFIAGLYQFQNLRGWSLLWATIQGSFYMVHWIPVMIVTTLKMCVQKERSRWVKTEHRGGTA
>NZ_CP046703|3668351:3726015|3696074_3697061_-|WP_114081511.1|DBSCAN-SWA
MNPYFNRNIPFSAFVQAFRHFMEQLLAESSIKIQEWKNKIVQALGEDGQVIIEVIPELERIIGKQPPAPELSGNAAQNRFNLLFQKFLQVFTTKDHPLVIFLDDLQWVDSASLKLIQLLTNEANQGYLLLIGAYRDNEVFPAHPLMVMLDEIRKTSVTVNSLNLKPLNQLQLNQLVADTLNCAEDVALSLSQLVDRKAQGNPFFATQILKSLHQDRLIQFNFVEGCWECDISQINQQTLADDVVEFMVFQLRRLPEATQQQLKLAACIRNQFDLKILAIVSKQSEVETADCLWKALQEGLILPQSEVYKFFVGSDNQAATQEHSGMVV
>NZ_CP046703|3668351:3726015|3678129_3678768_-|WP_114086201.1|DBSCAN-SWA
MMEQRQASIYKYTQLLWSVLLVLVIWNQPQSALADVNPQEITAIIRTRDIALQALNTRDFAKIQPYLHPNFTITTVDNQIFHKVPEFEKYWNQQFSSSIKDIKMQLKGDTLRTFLTPDIDVASGEAIASFYFKDGKAADMALRWTAVLQKLQDKWTIQSLHFSSNLLNNPVLNAAQQLGRILAIAAGVGGFLLGAVTMLLLRRKTKPRTERI
>NZ_CP046703|3668351:3726015|3679603_3681793_+|WP_114086202.1|DBSCAN-SWA
MTQEQLTMTTRNKLLKILAIFVLAVAVTFYGGRYAIADEPPPNASIICAETSTLEKNLRGKLGNKLLTYEGCPQEMGAWYMLPMAKNESDRMQAVHAALLPNNKVLIVNGSSNRNRVTTEGKIEDGVNTKNYDVVNNTSIFDPSLSDSLIENAKLDFNISPFQRIDSPLAEINGESNDPFCSGHLQLPNGDVLFIGGSRVYYPGVRFAGSKQANIYHWQEKDWQKQDQNIKRWENLGLTKDGHWYPTLIPLADGAIASFSGFTADPSQIVSTLVEIYDPNLKTWQSIDVKNLPNNPFLTQMNDESFGSDIIDLYARILPTKQKNRFIITGDGGGKNEPKIAHASTHSYFVTFNKDQDGKYSISFEPGPDRLAINKVYGTAVLDPSSPNGDVLLLGGIMGTNNIGIGPGKDVIKGASITASLERWKAPQDASTKGSWEIDNDFLAKIDEDILLNTEDIVDGKVKKFPLNYKYVKQSSKLGRYGKRAMEQAVILPTKEILVVNGGNYAETRPAYNPTLLIPDATKTGHQGFRTKLMNPDVEPRLYHNTALLLPDARVLVMGGNNSRAARFDKDGTVRLDTKNDFAFVNKGTDGNSGEIWQHAIFYPPYLFGESDRPEIAIAPEKLQYGASQTISVSNASTDQPGSIVLVKLGSVTHSFDNGQRLVDIQIDKKQIKYLSAQEQQLGGLKYNASIPFTAPTNDHFTPPGYYMLFYINSAGKPSHAKIVQLVNS
>NZ_CP046703|3668351:3726015|3709563_3710946_+|WP_114081516.1|transposase|DBSCAN-SWA
MLSPLFDAFVEASPVSVMMRVLMENIFNSSRMNQIFDTSSVRQYSQELLFSTQVDLMSLVVCGMYPSVHAAYQKKAVEVSVSATALYNKLQRIELPVSRALVHETASDLQQLLLMLNVERPSPLGKQYRLRIVDGSCLAGTERRLAALRPHAAKPLPGKTIAILDPGTKLVVDVIPCEDGHSQERSKFHQVLAQVQPQQVWIADRNFCTAGFLHTIAKLGAFFVIRQHGGLGYEPFGELQAVGLCQTGTVFEQQVEIVHEGGTFRCRRIVVKLTRPTRDQEWEIAIFTNLPPTDADGILVAQLYQGRWSVETLFQTVTQNFHGEIETLAYPKAALFSYCMALSAYNLLATLKAVLGSVHGVDKIDIGLSDFYLVDDIHSIYRGMMIAIPPVHWQFFEEFTNIQMVDVLQHLATKVHLKSFRKHPRSPKKKRPPLSVDGKHSHCSTTRKLKQYKAALDAIP
>NZ_CP046703|3668351:3726015|3721958_3722159_+|WP_012411649.1|DBSCAN-SWA
MSIADKSRALMVREHQQVKNRQQSMLMRAAQELGLPEEVSHYWNPIQGKVDASSRMIYGPSHASMS
>NZ_CP046703|3668351:3726015|3698592_3699861_-|WP_114080578.1|DBSCAN-SWA
MNSKYNFHYFQGSTLSDLFAQDIIDGSYGFILNYPATASWAAYPNRKQYFIQDGSSEASKTSFDKICQKEPWKNLAVLGDRIPGIVIIPPPKALLEYWQEHLGFKHSNIEMMDCSTYLDDLSHSERFDKLITLFPFDCLKPEKHAVASDTHYRLLSKVTLEELGVQCPKYKSYNLQQVNIADIQLPQFPYLIKTSHGLSGEGTYIIKSPSDLNYCLEEIKKYLDIKLLDTIIVSEFVKNEVQNYCVQFYVNKAGEITLIGTTGQLVTPEGNYLGGIIDYGKTDMSKFFEMIANVGDYAHKQGYFGVIGFDVLENQDGQFYAIDANFRVNGSTPLCLQRHTLLRLGKEVAKYSSSYRMEGTLESILITLKPELDRKDLIILSALEKAKYGKIYTELYAIVTGETIEQMQYIEQQLQTKGLQLL
>NZ_CP046703|3668351:3726015|3715874_3717320_+|WP_114080531.1|DBSCAN-SWA
MSIEELNQELTRLRQCLQQLTIDNAELSQAVLEYTTQLQQHKSEQQAALDERQRIEEELQTAQQFLYSVIQTMPVAVFVKDAADLRIVLCNQAAEKLAGVSADEILGKNDYDLFPKEEADFFTQRDHEALNSKTLLEIPEERIRKKSGETRILQIKKAPILDSQGQPKYLLVVRDDITEDKQAEAQLKQQAIELEQTLKELQSTQAQLIQSEKMSSLGQLVAGVAHEINNPVNFISGNLTYANQYIQQLLNLLHLYRINYPNPALEIQTTIQEMELDFLVEDLLKLLSSMEVGAERIQQIVLSLRTFSRLDEAELKAVDIHQGIDSTLSILEHRLKTRANHVQIQVLKDYDNLPLVECYAGQLNQVFMNILSNAIDALEEPLIQGKLSHNQPQIRICTQQLNPQKIVIRIIDNGPGIPEQVRQKLFDPFFTTKDVGKGTGLGLSISYQIITERHGGSLECVSSLEGGAELIITIPVAQLKQ
>NZ_CP046703|3668351:3726015|3711999_3713670_+|WP_114080533.1|DBSCAN-SWA
MSEALFCIENLRVAYPQRSGEEASWAVDDVSFTLQPGERMGLVGESGCGKSTIGRAVMRLLPASSCVEGKVTFQGQSVLDLMPNQLRKFRGEAIALIFQDPMTRLDPLMTIGKHCIETLQAHSPELSTREAKEKALATLAKVNIPASRWNQYPHEFSGGMRQRVAIALALLLNPKLIVADEPTTSLDVTVSAQILKELTRLCGEENMGLLLISHDLAMVAEYCDRIGVMYQGKMVEMGSTETVFRQPQHEYTRSLLKAALHIQAVNDDGELIIANDSEKQLPIINKQSPILSITELKQYYTIEPNFIERLFNTQAQTIKAVDGINLDIYPGEILGLVGESGCGKSTLSRTILQLIRPTSGKVKFLGQDLTTLSPQEIRSSRRQIQMVFQDPHACLNPAMTVGQSIADPLFIHNLANPVKAKEQVLWMLEKVGLTPSEVYYERYPSDLSGGQQQRVAIARALITHPKLLICDEPVSMLDASVQSQVLDLMLQLKEEFELTYLFITHDLWLARFLCDRIAVMNGGKIVELGLTKTIFANPQHPYTKTLLAAAPLLARA
>NZ_CP046703|3668351:3726015|3695511_3696060_+|WP_114081801.1|transposase|DBSCAN-SWA
MIIIDSQAVKNTCNASVESKGFCFYKATNGIKRHLAIDTLGFPFFTHCTRANVSDDAGLIEMFTLNIDYFKSKPIDIPKITILLDHGYHPEYLTQELEQIYPEIMTKIQFQLSTKPSKQEKAAQEKSGFVPAIARWVIERSNAWMERCKILVKNFERTLVSATAKLNLCFIRLMIKRLAAPS
>NZ_CP046703|3668351:3726015|3695206_3695515_+|WP_114081800.1|transposase|DBSCAN-SWA
MAYSSNLTDAEWEIFEPLLQEILPTKKQTRPTNWPKRDIFNGILYQLKNGCNWQDLPKDFPPYSTVYWHYKQWRAAGVFEELMSVLHGQVREQVKKNRTGRR
>NZ_CP046703|3668351:3726015|3709050_3709359_-|WP_114080570.1|DBSCAN-SWA
MLNLILTRCIKSQLLLISAAFLLAVQTSANAEQPLPSLTPAQAQSLSRDLVPYNSQDFFRQGKDSIEREIQILRQRQLRSIKPVLKIESVQQIKRPPTQQKP
>NZ_CP046703|3668351:3726015|3725001_3726015_+|WP_159402520.1|transposase|DBSCAN-SWA
MRFTKLNYCQYLLSSQINYTLTNLAEHLEQISHDKINRYLKNEKLTPRLLWDNVKDILQVSDSAYLVFDDTVLDKRYATEIETSKRQYSGNQHGVIQGIGLINCIYVNHEIGKFWIVDYRIYDPDRDGKKKIDHVTEMLQNLIYHKALPFQAVLMDTWYATNKLMLYIDGLGKYYYCPLKRNRLVDDTAGQKNYQRIELLSWDSQELKSGKIIKIKKFPQATKVNLFRVTVSTDRTDFIATNDLSQDSTDVVQKVCKVRWKVEEFHRELKQVTGIESCQCRKGRIQRNHIACAILVWLRLKHLAYQSYQTIYQIKHGLLSNYLVQQLKRPNVPMFIV
>NZ_CP046703|3668351:3726015|3708563_3708773_+|WP_114080571.1|DBSCAN-SWA
MIAQHYNSIHVENDLLQQIQIKENQLRIAQESNMIHVVEALQSQLLKLQCQLSEPQDVEVQALMSLLDD
>NZ_CP046703|3668351:3726015|3684370_3686500_-|WP_114086203.1|DBSCAN-SWA
MYVAVWPGNVYPLGASWDGKGTNFALFSENATGVELCLFDADNHENRLPLTEKNNFVWHAYLPGVGPGQRYGFRVHGPWAPELGHRFNPNKLLIDPYAKAIDGEISDTAAIFGYSLDAPEQDLAFSDLDNAETMPKCIVVDQSFDWGDDKLLSIPWHETIIYETHVRGFTKLHPEIPEELHGTYAGLAHPVAIQYLQQLGITSVELMPVHHFLSSPGFLVNKGLKNYWGYDSINYFTPYSGYSASGSVGQQVTEFKQMVKDLHSAGIEVILDVVYNHTGEGNHLGPTLSLRGIDNAVYYRLVKDNSRYNMDFTGCGNSLNVRHAQVLKLIMDSLRYWVTEMHIDGFRFDLASALARELYEVDNLAAFFDIIHQDPVLADVKLIAEPWDLGEGGYQVGNFPLRWSEWNGRYRDTVRDFWRGEDDSLGQFAYCFTGSPDLYQANGRNPSASINFITAHDGFTLNDLVSYNEKHNQDNGEDSRDGESHNRSWNCGVEGETNDPDVIRLRQRQRRNFLATLMLSQGIPMLLGGDEIGCTQKGNNNVYCQDNEIAWRDWSLQKSNSELLDFARELIYFRHQHPVFRRRKWFQGRPIHGFGISDIGWFNDDGSEMTEKQWLVSYAKAMEIFLNGEGIVTPGRRGERIIDESFLLFFNAHYETIEFALPNVFKDREWEIVIDTNESRFLSPGKLVMGEQTVPVTDRSLMVLRRLAS
>NZ_CP046703|3668351:3726015|3668351_3669392_+|WP_167756004.1|transposase|DBSCAN-SWA
MLTTAENSDWTDAQIAQNIGCSQALVRKWRKRWCQTRSLEEAPRPGRPRIFEAIIRAKVTAFALRVAAGIACSNPTDFDLPLARWSCSDIAAHLVTLGIVVSIATSTVWRWLKSERIKPWRFHTWMHRIDDNFVAKATPVLKLYAQAKFLIKAGFWVVCVDEKTSIQARSGLHPNIGAGVKQPVHFAARYARKGATHLFAALSVADGLIYGCCRPTKTFLDFQGFLLEVLIPEAIRRGMRHIYLILDNGSTHAPKQLQAWLNQKQKEDGWNFTVEVVWLPKYASWLDQIEIWFSILQRKLLTPNDFPDLKTLQQRITDFIVRHNDSAQPIKWSYTVAQMMEKFATN
>NZ_CP046703|3668351:3726015|3720610_3721669_-|WP_114080536.1|DBSCAN-SWA
MPESLTKLTYQTFQQGKNYFGLAHKILSSQLRNLVYPTLEQKTKPIPNELLVQLQQRLNQLLETDWQDAQKGVYPESLLFDNPWQDFFSYYPLMWLDSPQIWERVKQQNYQDFSPEIDTDGYPSYYVQNFHHQSDGYLSDLSANLYDLQVEILFGGAADAMRRRILAPLKQGLKASDSVTPKQVRILDVACGTGRTLKLIRAALSQASLFGTDLSPAYLRKANELLSQIPGELPQLLQGNAEELPYVDDYFHAVTSVFLFHELPASVRQTVIEQCFRVTKPGGVFIICDSIQLSDSPELEHIMDSFPETFHEPYYRHYTTDNLLERLQRVGFENIEIQTHFMSKYFIAHKPA
>NZ_CP046703|3668351:3726015|3702985_3703441_-|WP_114080575.1|DBSCAN-SWA
MWISAIVAYLHYLSFMLCFGALVSEALNLKKELSLNEAWKIVIADAVYGISATVVLVTGILRVIYFGKGADYYLSNPVFYAKVVVFIVVGLLSLYPTISFIGWVKSLQQGQAPKLEFLKLNRLIWLIRIELVGFTLIPLLAAIMARGIGIN
>NZ_CP046703|3668351:3726015|3675455_3676748_-|WP_114086199.1|DBSCAN-SWA
MSKVEGFRVRNYRVLRDITLGKLWNTQNAKPLTSMTAVIGKNGVGKSTIFDTFGFLADCLKNGVEEACDSRGRGGFERIRSQGQEGSIEFDIYYKEDHNARPITYELAIDIDSSGRPYVKRERLRQRRKGQSKGQPFSFLILNEGRGIAWKGEQEGKQVEEEKGDFDLSKLIEKIQRGEGKEESKETEVVELDDKRKLGIATLGSLKQHPRISVFRRFIEGWYLSYFTPDAARSLPLAGPQKHLNIHGDNLGNVVQFMEREHPKKFQSILEKISSKIPGVNKISTERSPDGRLLLRFNDKGFQDPFYAQNMSDGTLKVFAYLLLLEDPSPPPFLCIEEPENGLYHKLLETLAREFREHATGQKGGSQIFVTTHQPYFVDALKPDEVWVLEKGEDGFAKIKRASEDPLINNLVSEGLPLGGLWYSDYLDAS
>NZ_CP046703|3668351:3726015|3675199_3675466_-|WP_114086198.1|DBSCAN-SWA
MQVEYMHFEILVEDISGKIALEILVPKIINTEQHTFNIHHYKGIGRIPKNLTSTSDPKKRILLDQLPRLIQGYGKTLGACKKIKYQSF
>NZ_CP046703|3668351:3726015|3706544_3707078_+|WP_114080579.1|DBSCAN-SWA
MTKVTLYIAASLDGYIARSDGGIDWLSILDIEGEDYGYAAFYESIDAIVLGSNTYEVGLGFDEWPYPGKKSFVFTKRHLQSDREDVVFVSDTVKNALANIEAQGFKNIWLVGGGALINSFLQHSLIDEYIISTIPTILGSGIQLFPPPTPEEKLELINSKQYSSGLLQSYYRRKGKL
>NZ_CP046703|3668351:3726015|3700056_3700929_-|WP_114080577.1|DBSCAN-SWA
MTPTIIVHGGAKTITDDKVAANNAGCTAAVEAGWAVLISGGTAVEAVEAATRVLEADPTFNAGLGATLNSDGEVELDAAIMEGSLSWGAIAAVQGVRHPISVARKIMDEKPRLLVARGGERFARDCGAEMCKKEDLIAEEQWQQWKEDQEVIDRPNTIGCVALDTSGILAAGTSTGGTTKQQQGRVGDTAIVGCGLYADNKFGGCSTTGDGESIIPVVLAKTAIDFLTGDRHPDEAAQMAIDALVSKVKGEAGCILIDRQGRVGWAYNSSHMACAYMTAGQDKVAAFTKK
>NZ_CP046703|3668351:3726015|3704246_3705185_-|WP_114080573.1|DBSCAN-SWA
MNNLNFFSDYLIATLRLAVPLAFAALGGLYSERSGVLNIALEGMLLTGAFTSAAATFYTGNPWLGILASLIAGGLVGLLHAVLCVTLRVDQLVSGLAINLVAAGLTSFLARLVFSGSSTQQLPGIGTIIIPGLANIPLIGPLLFQSDFLVYLLFILVILTTYLLFKTSFGLTLRAVGESPKAADTAGISVQTIRYIAVVISGCLASLGGAYLTLVQVRFFAEGMSAGKGFIAIAALIFGRWHPVGSALACLLFGATEALQLRIQALGANIPYQFLVMLPYVIALLALVGLVGKSTPPKALGTPYFGENRHPD
>NZ_CP046703|3668351:3726015|3669431_3670172_+|WP_114081519.1|DBSCAN-SWA
MGFNARPVRATPELIESLDRISLPAIIHWKGYHWVVLYAQKDRKYVIADPAVGIRKLNHQELLEGWANGVMLLLTPDETRFYQQESDKIDGFGRFLKRVLPYSKILAEAIAINIVVGLLSLAYPLMMQLLTDDVLVRGDIQLLTTVAIAVITLNIFQAAIGIVQSHLVGQYAQRLELGLILDYGYKLLRLPLSYFEARRSGEVVSRIDDIERVHNLVSQIVLGLPSQFFIAVISGSSGAFMVVTKF
>NZ_CP046703|3668351:3726015|3703735_3703894_+|WP_159402519.1|DBSCAN-SWA
MTTNPQSLTGVVTAFPGDSSFDLQKLAGIGFVVANVKKFDGVDEYRNNRVLL
>NZ_CP046703|3668351:3726015|3701445_3702741_+|WP_114080576.1|DBSCAN-SWA
MLPKKTTASNQTQRWTFAQLFGLVKRNPLMISQWVILWVAVGTAGGLFAAFYWNVLEFLTHHLQRFEGFSLLIVMPLAGLVIGLVIHFLGNPGEIAVIVDNIHFRGGRLDVRKNPSMILASLISISAGGSAGPEAPLVQVTGSFGTWVADRLKLQGEDLRTLSLAAMAAGFTALFGAPLGGAMFALEILHHEHIVEYYEALMPAIVSSCASYLVFAAITHLGIAPTWHFPQYHLEKIDDFAIAIVFGIIGAVAGWIFMSIFRGCDYLFARIPGPIYVRTTLAGFGLGTLAALLPLTRYFGHEELEPVLTTNFGAIFLLTLALGKMAAISITVTGGWRGGFIIPLFFTGACIGKAVAVLIPGLNPALAMICTMAAVNAAVTRTPISTTLLLSKLTNLSPFTPILFASLIGFFLSPKVPLIASQLKSRREATE
>NZ_CP046703|3668351:3726015|3687140_3687386_+|WP_159402518.1|DBSCAN-SWA
MPSGICARTAVAINLNIRKMRELAGFKLKGINKSPLAYFFSNGIYVQSHCLRFSALGVFNKLTKLLCCRVQAKSLVEINLY
>NZ_CP046703|3668351:3726015|3689000_3691460_-|WP_114086206.1|DBSCAN-SWA
MKITFANLSLIGAIYISAIGNSNVQAQITPDGTLNTTVSGSNSYNITGGTVVSNNLFHSFSQFSIPTGGSATFSHNSNIQNIFSRITGNSISYINGSINTNSGVNLFLLNPAGIIFGANASLNVGGSFVGTTANSIQFADGNEFSTNITKSPLLTMSVPVGLQLGGNPGTISVQGVGNNSRLNPTTSVSGLTSTNGLQVLPEKTLALIGGDLVLDSSFLSAPGGRIELGSITQGSANIHLTPQALTFSYPSIGSSFGNIQMSQGAVASVRGTSPGSIQLQGKQIDLQDGSLLVVQNLGNSKAGDITVNATESLQVVGKSSDFRSSSGIVNEALLSGTAGNIVITTPTLTIDRGAIVMDRSYNSARGGNITINANAVSVGGVDPKDPSTVPIFGVLVAAAFGTKQGGDLSISTDSLSILGGANVGTRSFSSGQSGNVKVTADTVNVSSLDSPPGSLFISLLSANTFGPGDAGDLHLDTRKLSIQDGGLVSVSSVSSGNAGDLTINATESIDVRGMKDAENPSYIGAIARLFLLRTSTNINNNSTSKANAGSVTINTPKLTIRDGARVFVENEVQGDAGTLNVNANTLYLNNGSLSASTKAGQGGNINLQLRDYLLIRNGSFINAEAGAAGNGGNITINSPIILGWENSDIIANAFQGKGGNIEITTQGIFGLEYRPKLTSENDITASSQFGVNGTVNVNTIGFDPNSGLVELPVNVSDSSQKIATGCANSSGSSFVATGRGGIPQNPTQEISSDRTWSDIRDISAFHTTQPVKAQIQKPPEILVQATSWRRNAQGKIELISNQSPNQVQTALTCAATPQN
>NZ_CP046703|3668351:3726015|3691793_3695096_-|WP_114086207.1|DBSCAN-SWA
MIPEAQKQSTHLQIGRLLLENTPLHQQEEGIFAIVNQFNYGLELLEEPGEREHLARLNLIAGCKAKNSTAYATAVEYLKVAMLLLPINAWQSSYDLTLAVYESAAEAEYLNTNFESSKSLVDIILKNAKSPLEKVRTYEIQIQSYTAQNKFIEAIATGREALQLLDLTLPEDGNTQMIFDEYDQLQQMLVHQSIAALADMPEITDPKKLVALRILSGLFAPVYIAKPMLLPIKIFTMIKICIQSGNSPQAAVAYSLYGLFLCSIGAIEDGYSFGKLAIQLLDKFQNKELKSRVYLTFSLFIKHWKDSIKSTLGLFLDGLQSGLETGNLEYVGYCANCYSQFLFWSGENLENAVLEADKYCDLMQQLKQEVSLVWGNIWRQTVLNLQGEVVNPCCLIGKHFHEEEMLPTLIATNNINGICYVYLAKTLLAYLFGEYEPAWEYSQKFEQYEQGAAGLLIVPLRNFYQSLSLLALCSQVNEAQQQLYLQKVAENQAKMQEWANHAPVNYQHKYNLVLAEQARVTGDRVQAADYYEIAIQEAIANDYIQETAIANELAAKFYLEWGKEKAAEGYLQQAYYCYARWGAKAKTDDLEKRYPKLLKPILQQQEFYFNPLESITTIGSISTCATSSTNISDTLDLTCILKAAQTISSCIELDVLISSLTRIILENSGAKTSVLILPQEDIWQVRAITFIDQQSNSQTDVKTILDSQLLDTCQDIPIKLINYVKNTQETVIIDNCKTNIPGVIGEYMLLHQPQSVLCTPIINQGHLVGIIYLENQLNQGVFTTNRLQVINLLSSQAAIALENAKLYQQAGQALEDLQQAQLQIVQSEKMSALGNLVAGVAHEMNNPLGFIAASLKQAKPIFLDISEHLKLYQEKFSEPGDEIINHAEEIDLDYTLEDLPKIIDSMTMACERLENISTSLRTFSRADRDYKVPFNIHEGIDSTILILKHRLKANEHRPAIEVVTNYSNLPPVECFPGQLNQVFMNILANSIDALDESNTDRTFEDIKANPNRITITTSLKYQQVEVKIADNGVGMSESVKEKIFEHLFTTKGVGKGTGLGLAIAHSIVVEKHSGNLNVNSTPGEGTEFVISLPILAQTQS
>NZ_CP046703|3668351:3726015|3707214_3707562_-|WP_012411639.1|DBSCAN-SWA
MSADTQIVAYLEESEFDVVLNGSEEKVVVVDFTATWCGPCRLVSPLMEQLAEEYKGRAKVVKVDVDRNKPIFKKFGLRSIPAVLIFKDGILAETIVGVSPYEQFSEAVQKLLEVV
>NZ_CP046703|3668351:3726015|3724069_3724579_+|WP_012411651.1|DBSCAN-SWA
MRDAVTSLIKNYDLAGRYFDRNAIDSLKSYFDSGTVRVQAAAAINSNAAALVKQAGLKLYEELPELIRPGGNSYTTRRYAACLRDLDYYLRYATYALVAGNTNVLDERVLQGLRETYNSLGVPIGPTVRGIQILKDLIKEQVAAAGVVNTAFVDEPFDHITRELSEQDI

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_167756004.1|3668351_3669392_+|transposase	IS630 family transposase	NA	NA	NA	NA
WP_114081519.1|3669431_3670172_+	hypothetical protein	NA	NA	NA	NA
WP_114081265.1|3671750_3673454_-	D-aminoacylase	NA	NA	NA	NA
WP_114086198.1|3675199_3675466_-	hypothetical protein	NA	NA	NA	NA
WP_114086199.1|3675455_3676748_-	AAA family ATPase	NA	NA	NA	NA
WP_114086200.1|3676837_3678121_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_114086201.1|3678129_3678768_-	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_114086202.1|3679603_3681793_+	DUF1929 domain-containing protein	NA	NA	NA	NA
WP_114086203.1|3684370_3686500_-	glycogen debranching protein GlgX	NA	NA	NA	NA
WP_159402518.1|3687140_3687386_+	hypothetical protein	NA	NA	NA	NA
WP_114086205.1|3687396_3688911_+	glycosyltransferase	NA	NA	NA	NA
WP_114086206.1|3689000_3691460_-	S-layer family protein	NA	NA	NA	NA
WP_114086207.1|3691793_3695096_-	GAF domain-containing protein	NA	NA	NA	NA
WP_114081800.1|3695206_3695515_+|transposase	transposase	A0A0N9SHJ4	Paenibacillus_phage	2.1e-07	30.1
WP_114081801.1|3695511_3696060_+|transposase	transposase	NA	NA	NA	NA
WP_114081511.1|3696074_3697061_-	AAA family ATPase	NA	NA	NA	NA
WP_159402428.1|3697063_3698536_-|transposase	IS66 family transposase	NA	NA	NA	NA
WP_114080578.1|3698592_3699861_-	carbamoylphosphate synthase large subunit	NA	NA	NA	NA
WP_114080577.1|3700056_3700929_-	peptidase T	NA	NA	NA	NA
WP_114080576.1|3701445_3702741_+	chloride channel protein	NA	NA	NA	NA
WP_114080575.1|3702985_3703441_-	DUF2214 family protein	NA	NA	NA	NA
WP_159402519.1|3703735_3703894_+	hypothetical protein	NA	NA	NA	NA
WP_114080574.1|3703862_3704126_+	hypothetical protein	NA	NA	NA	NA
WP_114080573.1|3704246_3705185_-	ABC transporter permease	NA	NA	NA	NA
WP_114080579.1|3706544_3707078_+	dihydrofolate reductase	NA	NA	NA	NA
WP_012411639.1|3707214_3707562_-	thioredoxin	A0A1J0GW78	Streptomyces_phage	4.9e-13	45.3
WP_114080572.1|3707781_3708108_-	hypothetical protein	NA	NA	NA	NA
WP_114080571.1|3708563_3708773_+	hypothetical protein	NA	NA	NA	NA
WP_114080570.1|3709050_3709359_-	hypothetical protein	NA	NA	NA	NA
WP_114081516.1|3709563_3710946_+|transposase	transposase	NA	NA	NA	NA
WP_114080534.1|3711521_3711815_+	hypothetical protein	NA	NA	NA	NA
WP_114080533.1|3711999_3713670_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	6.0e-24	37.4
WP_114080532.1|3713747_3714692_-	hypothetical protein	NA	NA	NA	NA
WP_114080531.1|3715874_3717320_+	PAS domain-containing protein	NA	NA	NA	NA
WP_114080530.1|3717622_3719482_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_041565664.1|3719589_3719817_+	hypothetical protein	NA	NA	NA	NA
WP_114080536.1|3720610_3721669_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_012411649.1|3721958_3722159_+	hypothetical protein	NA	NA	NA	NA
WP_114080529.1|3722290_3723712_-	type I glutamate--ammonia ligase	NA	NA	NA	NA
WP_012411651.1|3724069_3724579_+	allophycocyanin subunit beta	NA	NA	NA	NA
WP_114080528.1|3724673_3724934_+	hypothetical protein	NA	NA	NA	NA
WP_159402520.1|3725001_3726015_+|transposase	transposase	NA	NA	NA	NA

Sequences of DBSCAN-SWA_6

Nucleotide sequences of DBSCAN-SWA_6

>NZ_CP046703|6496978:6567177|DBSCAN-SWA
TATGGTAAATCGACGGACTGCAGAAATATTGCGAAGTGGCCAACCTGATGAGTCCCTCCAAGTTCAAGGCTGGGTGCGGACGAAGCGCGAGTCCAAAGGGTTTGCTTTTATTGAAGTCAATGACGGCTCATCACTAGCTAATTTGCAAGTCGTCATCAATCAGGATTTGCCAGATTACGAAGCTATATTGAAAAAACTGAATACAGGTGCTGCTGTTGAGGCTACAGGGGTACTAGTGGCTTCTCTTGGTAAAGGACAACGAATTGAGTTGAAAGCCGAGTCCGTGAAAGTTTACGGCGAAGCTGATCCCGATACATATCCCCTACAAAAGAAACGCCATTCCTTTGAGTTTCTGCGAACCATTGGACATTTGCGATCGCGGACTAATTCTTTTGGTGCAGTTTTCCGCGTCAGAAATGCTTGTTCGGCAGCAATTCACCAATTTTTCCAAGAAAGAGGGTTTTTATGGGTACACACCCCTATCATCACTGCTAGCGACTGTGAAGGCGCAGGTGAACTGTTTAGCGTTACCAGTTTAGATTTAAAGAATATCCCCCGCACAGAAAACCAAGCAGTAGATTACAGCCAAGACTTTTTTGCGAAACCCACATATTTAACAGTTAGCGGCCAGTTGGAAGCGGAAGTGATGGCAATGGCGTTTAGTAACGTCTACACCTTTGGCCCTACCTTCCGTGCCGAAAATTCCAACACCTCGCGCCACCTAGCAGAATTTTGGATGGTTGAGCCGGAAATGGCTTTTTGTGACTTAGAAGGCGATATGGATTTAGCTGAGGCGTTTCTCAAACACATTTTTAAATATGTGTTGGAAACTTGCCCAGAAGATATGGAATTTTTCAATGAACGCATTGATAAGTCTGTGTTGGCAACAGCCGAAAATATTATTAATAATCAGTTTGAGCGCTTAACTTATACAGAAGCCATCAAAGTTTTAGAAAAAGCTGATGTTAAATTTGAATATCCTGTGAGTTGGGGTTTAGATTTACAATCAGAACACGAACGCTACCTAGCTGAACAACAGTTTAAAAAGCCAGTAATTGTCACAGATTATCCAGCGCAAATCAAAGCTTTTTATATGCGCTTGAACGACGATGAAAAAACCGTCCGCGCAATGGATATTCTCGCACCCAAAATTGGCGAGATTGTAGGTGGTTCTCAGCGTGAAGAACGCCTAGAAGTTTTAGAACGCCGCGTGTTAGCGCAAGGATTAAAGCCAGAAGATTTGTGGTGGTATCTTGATTTACGTCGTTATGGTACTGTTCCCCACGCTGGTTTCGGACTGGGTTTTGAACGACTCGTGCAATTTATGACGGGTATGGGAAATATCCGCGATGTGATTCCTTTTCCGCGTACACCACAAAGTGCTGAATTTTAGTTAAATTTGTAAACCTGGCCATTTATAATCCAATACAGTTCAGATAAGACCAAAAAACTTGTAGAGAAGGCTATTTATCGCGTCTCAAAACCCACGATTTTGTACAAGTAGCGCTTTGAACCGTATTGATTTATAATCGCCAGGTTTTTAAACTTTGGGGATCAACAAAAATCCAGTTAAAAACATTTATCATCAGCCTAAAAGACCAAATAATTGGTAAATTTCGGCAAAATGCCAGAATCTCAGGAAGAGTAGTTTTGGATGAAAAAGCCTCTTCCGTAAAATATGAAGTTGTAGTGGAGAAAATTAAGCGATCGCTCCTAGTTTGGAGAGTTTCTCCATCTACAACTGGAAAAGCTATCTTAACCTTGTGGATTCACATTTAACTTGTAGATACGGGCAAATTTCGCCTCTCTATCAATTGTTAGATGTGTTAGGCGTTTTAACCTGACGTGCCATGTCTAGGTAAGCACTCATATTCGCACCTGGACGACGACGACCATTAGAGCTAGTAGTCGAAGGAGCAAGATATTTTGGTGCAAAAGTGGTTTCAGCAGGTGTTTTTTGGCTAGCGGTGGCGGCTGCTTTAGCGGGTTCAGCTTTGACAGCTTTACCATTCTGAGATGCTTCTACTTTGGTTTTTGTCGCAGTTGTGGTTGCTTTAGCAGTCTGAGGTTCAGGGCTTTTTGCAGCCGGAGAAGCTGCTGGTGCCGTAGCCTTTTTACCGTTTGATGCTGCTGGTTTCGATTGACTGGTTGCTTCGTCCAGTTCTAAGAAGTAACCATTGCTTTGTTTTTTACCAGGTAACAACCCAGTCACGAAACCAAGAATCCCAGTTACGAAACCGAGAATCCCTGAAATTAACTTTTTGATAAAATCCATTACAATTACTCCTGCCTTGTATATTTGGAACTCGACCGTAATTGTTAAAAATTACGAAAAAATGTAACATTTTCTGCATTGGTGTCAACTCATTCTGGTGACAACCATTATAGATTTGTGCTTAATCAACATTGTAGTAAAACTATAGGGCAAATGTTCTTTATGCAAGCACTTGCGACCTTCATACACCGAGAACTAATTATTAAATTTTACTGTAACTAAGAGCAAGATTCTGAAAGCAAGCTTTATAAAAATTAACACTTCTTCGTTTGAAAATTATTGATTGGAAAAAAGCAAGCGGTTTACTTTTAACCAGTGGCAGGAGTGTCATAGATTGTTCGCAGATAGCAACAGTACTCAGTTACATTTTGTACAGACTTCATTTAGCCAGATGTGAGAGATGAATACTGAAAATCAGCAGCGCAATCCTGTGCTATTGGTACACGGCATTGACGATAGGGGGGCGGTTTTTCATAAAATGGCAGGTTACTTAGGATTACAGGGGTGGTCTGTATATTCTCTGGATCTGGTTCCTAATAATGGTGATGTGGGCCTTGATAAATTGGCAAAACAGGTAGCCGATTATGTTACAGACACCTTTGCACCAGAACAAGAGCTAGATTTAATAGGCTTTAGTATGGGAGGAATTGTCAGCCGTTACTATATCCAGCGACTGGGAGGAATTAACCGTATTCAGAGATTTATTACGATCTCTTCACCCCATAATGGAACTGTGGTTGCTTATGGTTCCCAGCGTCCTGGTTGCGTGCAAATGCGCCCCGACAGCATTTTTCTCAAGGATTTAAATTCTGATGCTGTAATATTGGAGCAATTAGATTTTACTTCGATCTGGACACCTTATGATTTGATGATTGTCCCAGCGAATAGTTCACAAATGCCCGTAGGAAGCGAAGTAATAGTACCAGTTCCCCTACACCCTTGGATGCTAACAGACCCAAGGAGTTTAGCAGCAGTAAAAGCAGCTTTAACAAAGCCTATTAAGCTACCCTTCCTTAAAAAAGCATCCAGTTAGTAGCCAAGATACTTACCACCCTGAATCTATTCATCTTTAATTACGAATTACTTAAGTTCTATCCCCAATTTGCGTATGTTCGTAACTCCCAAAAATCGCCTCTGGGTGACGATAATACTTGAATTCCATAAGGTTATAAAAAGGATCTTCTAAAAAGAAAGTGCGATGTTCAAGAGGAGAACCGACAAAGCGATTTTTGGTTTCTTCACGAAAAAGTAGCTGTTGTTGTTGTGCCCTTTCTAGTAAGTCTTGCCAGTCACGTTCTTGGGTAAAAATTAGCCCAAAGTGTCTGGGATATATACTGTGTTGTGGTATCAAGGGTTCTTTGGTTATGTGAGCCACTAGTTGATGACCATAGAGATTTAGAATCAGCGCGTGATGGTTTTCACGACCAGGAATACAGCCCAATCCATCCACGTAATATACTTTTGTTTGGGCAATATCAGTCACAGGGAAAGCAAGATGGAATAAAGTTTGGCTCATAGCTTTTGGGAAAGATATTAGTAGTTGATGCTATCTACAATTTATTCTGTTAAGTTTTGATTGTCGTCAACTTGAACACAGTTTTAGCTGACAATAATTTATATCCTTGATCTTTATAACTAAAACTAGGAACTGAGTACCATTCAGTCACTGCAACTTGTGGCTAAAGACTTCGCCCTATATTTACATAATTTACACTTAATTCTTTAGGTGACTCCTTTCTCTTGTGCAGGTATAATAATTTATGTTTGCCTGGTCAGACACTCAGTAACGGAGATTTCAAAGCTGACAACTTTATGATAGATGGTGTGTTGAAAACTTAATGCACCATAATAAAGTGCTTTGGATCAGTTACTAGAAGAGTCCACCCCAATACTGCTCGGGTTTTGCATTTTTAACTCGGAATTGGGTTTTGGGAAAAGGTTAAAGGGTAAAGGTTAAAGGTTTTTTCTTTTCCCTTTCCCCTTCCCCTTTTGCCTTTAACCGACAAGTATTGGAGTCCACTCAACTAAACAAAATTTTTGCATTTTGTTTAATCCACCTCCTTTAATAAATATTGCAGTCTATTATGTAAAACGTTGTTTGTGGTTTTACACTCAGCTTTGAGGGTGATGGGATGCAATTTAGTTAACAATACAAACATATTACTTTAACTGGAGAGGTTTTAGGAACTAAGCACTAAGCATGACAAATTCGTTATTCTGTTCATGTTAAGACAAAATTACTCATGATTAATTGCTGATGTCATCCTTAATTGATTCTGTTAATCCCTGGTTGGTGGCAGTAGTATTAAACACAATTCTATTGGGTTTAGCTTGGATTGCCCCGAAAAAGCTACTTACGCCTGCTGGATCATTTCATGCGTGGTTTCTGGCCATCCTAATTTGGGTAACTCTAGGCTGGCAAGGATATACAGTAGTAATGTTCTATTTTCTGGTTGGTTCTGGTGTTACCCGCATCGGTATGGCGCAGAAAGAGGCTGAAGGAATTGCCGAAAAGCGTTCTGGAGCAAGGGGCCCTGAGAATGTCTGGGGGTCAGCTTTGACCGGGGCGCTGTGTGCCTTGGGAGTAGGGATAATAAATTCGGGATTTCTCGTACCTAGTTCCCAATCTTTAGTTCCCAATCTCCAGTCTCTATTATTACTAGGCTATGTAGCAAGTTTCAGTACCAAACTGGCTGACACTACTGCAAGTGAAGTTGGTAAAGCGTATGGTAAAAGCACCTTTCTAATTACTACACTCAAACCAGTGCCTCGCGGTACAGAAGGAGCGGTCAGCTTGGAGGGGACTTTAGCTGGTATTGTGGCTTCTGTAGCGATCGCATTTGTTGGTTGGGGAGTTGGTTTAATCGATCTATTAGGAGTCGCTTGGTGTGTACTGGCAGCATTTATTGCCACTAACTTAGAAAGTGTGATTGGGGCAACACTGCAATCTAAGTATACCTGGCTGACCAATGAAGTAGTAAATATTTTTAATACATTAATCGGTGCGATCGCGGCTGTGCTACTTTCCTGGACATGGGTAAATATCATTAAGTAGATTGAGCATTGGGAATTGGGCATTGGGAATTGGGAATTGAGTAAAACGGTTCCTCTTCTGTGAGTTCTGAGTAAAGAAGTGAGATTCTCCACTCAGTACGAAGCAAGGTCTAAAGGCCCCGCTACTGCTAACAGCGCCCAATACCCAATACTCATGAGAGCCAGTGGTAGAAAATAAGCAATCTGCTTTACTACTGCACTACCGATGATATTTTCAATCCTGTTTTGTCCCCGCTAGACTGTAAACATAATCATGGAAAATTATTGTATTGAGTAGCTATATAATTTTTTGACCGTTTAGATGTAATTAGTTCATGGAATCTTTATCATTGTTATTCATCAACGACCAGATGATCTCTATATGATTTAATTTAAAAGTCCTATAAGTGTTTAACCATTTTCACATAATTAATTCATGGAATCTTTATCATTTTTGACAATTAATGACCAAATAATTTCTATTGAGGAAGCTGTAAAGTACCTGCAAGCCTCTGGAAAATTGGGGCAGTTCATTGGGGATATTCTCCGCCAGCACGTAATTGAGCAAGAAATCCGAACACGAGACGATATTGAAATTGGTACAGCAATAACCGAACAGTCCATTATTGACTTTAGACTGAAAAATCAACTGACCGATCCTCAAAGTTTTCAAGAATGGTTAAAAACCAATAACACAGATTATGCCGCATTCCATACATCAGTTACTTTTGGTTACAAGTTAGAAAAGCTGAAAGCTGTAGTCACGGAAGCAAAAATCCAAGAATATTTTATTGAGCGCAAAATCTTTTTGGATCGGGTGGTACTTTCTCGGATAGTTGTTAATAATCGAGAATTGGCAGACGAACTACAAACCCAAATTGAAGAAGGAGGTAGTTTTGAGCAACTAGCTAAAGAGTATTCACTTTCAGATGACCGAATTGTGAACGGCATGATGGGAATAGTCAGCCGAGGAAGTATGCCAGATATATTACGGGCAGCTATTGATGTGGCAAGTCCTGGACAATTAATAGGACCAATAGAAATCGTTGGCAAAGACTCTCCACAAGGAGAAGGACCTTATGGTTTGTTTCGAGTAGAACAATTTCTGCCAGCGTCTTTAGAAGATACTCAACTCAAGCAAGCACTACAAAATGAGTTATTTGAGAAATGGCTAGCAGAGAAAATTCAAAAACTGACAGTCAAGCTACAAGTGAGTTAAAAATTCTGGATAATGAATCTTTACGATTAAAAGTGCTAGCTTCTTTGCCCTGGAATCAGCCGCCGCTATGCTGGTTGACTCCCGAACAACAATCCCAATTGGAAAATGAGTGTCAAACTCGTCAGTATCGTTTGGGAGAAAAAATTTGGTCTAACGATGTCGGTCGTTACCAATTCTTAATTGTGGCTGGAAAAGTTCGCTTACGAGAAGAGGGAGTTGGCAAACCTTTGGCAGCCCTAGAAGTGGGAGATTGGTTTGGTGATTTACAAAAGTTGTCTGCGGATTTTAAAGCTGTAGCTGCTAGCAAAGAAGTAATAGTAGTGTGTTGGGATACAGCCCTGTGGACAGAATTTTCTAACCCACAAATTCAGGAATTTTGGCAAGTCTTACCAGTGGATATGGAGGGAGAAAGAGAGACATTTTCCTTCTCTTCCACTCCTTCAGTAACAGTCTCAGATGGGACTTCCAGCCCTCACAGCCTCCAACCCCAAAAACGACTCCCAGCCGCGAATTTAATCATCTCAAATTATCCATTTGTTGCTAGTTGGAACACTGCGGCTGCTTGTTTAACAATGGTGGCGCAACAGCTAGAAAACTCTGTGCAACTGGAATGGGTGCAACGTCAACTCAGAGGACAACGCCCAAAACAGGTTGTGGAAGCAGGAGAAAAGTTAGGGTTAGTGTTGCGGCGGTTACAAGTGAGTTGGGGTGAGTTGCGACAACTGTCATTTCCAGCTTTACTGTTGTGGAATTCTGACTCACCCCAGAGTCCATCCTGGGTGGTAGCTTATGGAGTTAAGGGCGATCGCTTAATTATCGCTAACCCTCTAAATCCCGATCGCATTTGTGAAAGCTTACCGCAATCCATAGTTGAGGCATCGTGGGATGGACGATTGTGGCAAGTAGAACTCATATCTAAACAAGAAACATTTAACCTCAGTTGGTTCACCCCAGCAGTTTGGAAGTATAAGGGATTACTAACAGAAGTATTATTAGCATCTTTTACCTTGCAGCTTTTGGGGTTAACAACACCACTAATTACGCAAGTAGTTATTGATAAAGTAATGGTGCAGGGGAGTTTGCCGACTCTTGATGTTATGGCGATCGCACTTCTTTGTGTAGCCATATTTGAGTCCGTACTTGGCATTCTGCGCCTATTCATCTTTACCCATACAGCCCGTCGTCTGGATTTAAGTTTATCAGCACAGCTATTTCGCCATCTGATGCGCCTGCCTTTGGCTTATTTTGAGTCGCGGCGCGTCGGAGACACAGTAGCACGAGTCCAGGAACTCGAACAAATTCGTCAGTTCCTCACAGGTACAGCATTAACTGTGATTCTAGATAGCATCTTTGCTGTGGTTTACCTAGCATTGATGTTTTACTATAATGTCCCACTCACCTTTGTGGCTTTAGCAGTACTGCCGCTATTTGCGACTTTGACGATAGTTGCAACACCAATTCTGCGTAACTGGCTCAACGAAACTTTTAACCGGAGTGCCGATAGTCAATCCTTTTTAGTAGAGACAATCACGGGGATTCATTCCGTTAAAGCCCATGCAGCCGAACCAGTAGCCCGCGATCGCTGGGAAGGCTTATTTGCTCGCTTCATCCGCACAGGTTTTAAAGCCTCTACCACCTCCAATATCAGCAGCAACATTGGTGACTTCCTCACTAATTTTTCCACCATGCTGATTCTCTGGTTTGGAGCCAAATTAGTCATAGAACAAAAGCTGACAATTGGACAACTAGTTGCCTTTCAAATGCTATCTGGCAGAGTCACGGGCCCACTTTTGCGCTTAGTACAGTTATGGCAGACCCTCCAACAAGTGCTACTTTCTGTAGATCGCATTGGTGATATTCTCAACGTCTCCCCAGAAGCTGAACTAGGAACTGGTCTAGTTTTACCACCTCTGAAAGGACAAGTCACCTTCGAGCAAGTATTTTTCCGCTACCGCCCGAACTTTGAAGCAATTCTGCGGGGAATCTCTTTCAATGCTGAACCAGGGCAATTTGTTGGCATTGTCGGACGTAGCGGTTCTGGGAAAAGTACCCTGTCTAAGCTATTACAACGCCTTTATCAAATTGAATCAGGACGCATCTTAATTGATGGTTTTGATATTAAAAGTGCCGATTTAGCGTCATTGCGGCAACAAGTTAGTGTAGTTCTCCAAGAAGACTTTTTATTCAACGGTTCTATTTTGGAAAATATCACTCTCGGTACTCCCGACATTACCGCAGAACAAGTGGTAGAGGCGGCAAGACTAGCAGTAGCACACGACTTCATCAGTCAATTACCCTACGGTTACGAAACCAATGTGGGTGAACGCGGTACAGCTTTATCTGGCGGACAAAGACAACGTATTGCCCTCGCAAGATTATTTCTTTCGCAAGCGCCGATTTTAGTTTTGGATGAAGCTACCAGTGCTTTGGATAGTGAAACTGAACAACAAGTACTACAAAACCTGCAAAAAGTTTCCGCTAACCGTACTGTGTTTCTGATTGCTCACCGTTTTGCCCCTCTCAAACGCGCCGATTTGATTTTGGTATTAGAACAAGGCGTGATTGCCGAACGTGGGACTCACTCAGAGTTATTGCAACAAAAGGGTTTGTATTGGTCACTATATCAACGGCAGCAAGCAAATATTTAGTAAGCTTTTAACTTGTGCTTATTTGAGCCCTGAAAAGCCGCTTAAAGATAGGCTTTGGCGAATGGAGTTATACTTCATTCGCCTTTTAAATTGCTTAAGTATGCAGAAAACTGTAATCTTACTTGCTAATTACGTGATTTTATAGTTAAGTGTATTTGTAGCACCTGTCTTACAAAGAAATATCTCCCGGCTCAATCCCTTATATATCAAGGATTTGAGTACTTTTTATGGTGCAAATTTACTTGAATATACGAGGTGAAACTACTAATGTTTTTTACCAAAGGCTGTAACTCTATTAATGAAAATTCTGGTGTAAAAGCCAGCCTTGTATCATCAAAAAAATCTAATAGTTTTGATAATCAGAATAATGACTCTAGCTTCAGTCTGAGTGGTGTAAATAGTTTTAGAGCCAGCGATCGCAGTAGTTATACTTCTACGGAAATCGACGCTTTCGGAGTTAAAAACAATTATGCCAAGAAGAGTAGTTTAAGCAACGAAAATACTACTCAAGCGATCGCTGCGGCTGCTATTCAGCCAGACCTGATAGCACGTACCGTTTCAACTCCCAGTTCTGCCGCAGCTGGCAGTACCATTCAACTGAGCTATGAAATTGAAAACCAAGGCAATGCCAGTGCTGGTTATAGTTATACCAAATTTTATCTGTCTCAGGATCTCTCTTTAGGGAGTGAAGATATATTTTTAGGCGATGACTATGTTGATAACATTCTATCTGGTTACTACAGATCAGAGTCAACCACACTCACTATCGGCAATAGCGTCGCCGCAGGTAGCTATTATTTGGTGTATCAAGCCGATGGCTATAACTATGTTGCCGAAAGCAACGAAAACAACAACGCTGTTGCTGACGTAATTAATATTACTAAACCAGACCTGATAGTACAAAATACCTCAAATTCCAGTTCGGCGGCGGCTGGAAGTAGCATTCAACTAAACTATCAAATCAAAAACCAAGGCAATGCCATTGCTGTTGCTAGTAACACCAAGTTTTACCTCTCCCAAGATTTAAATATTGGAAACGAAGATGTGTACTTGGGCTATGACTACGTTAGCGGCATTGCTGCGGGTAGTTATAGTTCCGAGTCAACCACACTCAGTCTTGGCAGTAACATCACTCCTGGGAATTATTACTTAGCATACATAGCCGATAGTGATGGGAATGTTGCTGAAAGCAATGAAACTAACAACGGTATTGCCGGAGTAATCACCATTACTCCAACTCAAAAATCAGACCTGATAGTTCAAAATACCTCAGCCCCTAGTACAGCATCAGTTGGTAGCACTATTCAACTAAGCTATCAGGTCAAAAATCAAGGTGTTGGTGGTGCTGTTGCAACTACCACCAAGTTTTATATATCCAAGGATAATGCTTTTAGTAATGATGATGTGTTGTTAGGCTCAGATGCCGTTAACGCTATTGCCGTAGGTGCTACTAGCTCAGAGACAGCATCGCTGATCATCAACAATGCGATCGCTACAGGTAACTATTACTTGCTCTATCAAGCTGACGGCGCAGGAAATGCAGTTGAGAGCAATGAAAGCAATAACTTTGCTAGCAAAGCGATCGCCATTACCCAAGCAGACTTAATAATACAAAACGCTGTGGCTCCAGCTACAACAGCCGTTGGTGGCACCATTCAATTGAGCTATCAGGTGAAAAACCAAGGTGTTGGTGGTGCTGTTGCAACTACCACCAAGTTTTATATATCCAAGGATACTGCTTTTAGTAATGATGATGTGTTGCTCGGCTCCGATGCCGTTAACGCCATTGCCGCAGGTGCTATTAGCTCAGAGACAGCATCGCTGATCATCAACAATGCGATCGCCGCAGGCAACTATTATTTGTTGTATAAAGCCGATGCTAATGGCAATGTTGGCGAAAGTAACGAAACTAATAATATTGTCAGCAAAGCGATCGCTATTAATGGCCCGAAACCAGACCTAATTATCCAAAATATTTCGGCTCCTAGTCTTGTTGACCCCGGTAGCTTAATCACTGTCAATTATCAACTAGCCAATCAAGGTACTGCCAGTGCTGGTTCTAGTACAACGAAATTTTTTCTTTCTAAAGATACGACCTTGAGCGGCGATGACACATACTTAAGCTATTCCCGAAGCTACTTATACTCTGGATTAGGCGCTAGTAAATATAGTGCAGAGTCTTACTCTTTAATACTCAGCAGTAATATTACTTTTGGAAATTACTACCTGCTATTACAAGCCGATGGCAATAGCGAGATTTTTGAAAGTAATGAAAACAATAACGTTACGGCCAAAGCAATTACGATTGCGGCACCAGACCTATTAATACAAAATCCTTCGGCTCCTGCTAGCGCCAACATTGGTACAACAATCCAACTAAGCTATCAGGTGAAAAATCAAGGTAATGGTAAAGCTGGTGTTAACACGACACGCTTTTATCTTTCTAACCCTGTTTTGTCACTCTGGCGGTAGTATAATAAGGTACAAATGCTAGAACCAAGACACAGAGTATGGTACAGCCCCGTCCAGCCGCACCAACAGTTAAATTTGTGGACGAATATTGCCAGTGGTATAAAAGCCTGTTTCCAGATGTTAGGAGCTTCGAGGCTTTTAAGTACCTTCATGTAGGGTGTATTTCTGAACTAAAACGGAAAACCCTACCAGAAATAGCAAAGATTGTAGGATTGGATAACCAACAGGGTTTACATCATTTTTTAACTACATCACCGTGGGATATAGAGAAGTTAAGAGATTTGCGATTAGAGCTAATTTTACAAGTACTAAAAGGTAGACCAATCATTCTGATTATTGATGAAACAGGAGATAAAAAGAAAGGGAATAAGACAGATTATGTGAAACGACAGTATATAGGAAACTTGGGGAAAGTAGAGAATGGAATTGTGGCAGTAACAGCGTATGGCGTATTCTGCGGTATGACTTTTCCACTGCTATTTGAAATATATAAGCCTCGTGAAAGATTAAAGCCAGAAGATAAATACCTAACCAAGCCACAAATAGCAGCAATTCTCATGCGAAAGCTCAAGTCAATGGGCTTTAAATTTAACTTAGTACTGGCAGACAGTTTGTATGGAGAAAGTGGAACTAACTTCATATCTGTGTTAGATGAAATGAATCTAAACTATATAGTAGCGATTCGCTCAAACCATGATGTGGATTTACTTCCAAGACAATATACTCAATATTTAAAGTGGCACAAGTTTAAACGAGTATTTTCTGATCTGAGTAGTGAAAATAGGTTTATCAGAGAAATAATTCATGGTAAACGTAGCGAAAATAGGTACTGGCAGATTACCACAGACCGAGAGAAATTACCTGGTAACACTACTTGGTATGTAATGAGTAAATACCCAGACCTTACACCAAGAGATGTGGGAAACTTTTACGGTTTAAGAACTTGGGTTGAGTATGGGTTGAAGCAAAGCAAGAATGAATTAGGTTGGTCAGATTATCGGCTAACTCACTACCCGGATATTGAACGCTGGTGGGAGATTGTTTGTAGCAGCTATTTAATGGTTAGCCTACACTCTGAACAAATCCAGTCTTCTGTGCCAAAATCTCCATCAAAATTAGCTTCGCATCCCTGGTGGAATGATGAAAAAGGCTGGAAGAATATTCTTAACAATCTCCGCTTAATAATTCAACCTTTTACCTTATTTAACCTAATATATCCCTGGTTAACAGTTTTTCCTATTCCCCAATTGTCCTTGGGTTTTTCTAAACTTCAATCTATTATTTATAGCCTCACTAGTTCAATTTTTATTTCTCTAACTCACCCTGATTTCTACTTTTCCTCTGCCTAGAGTGACAAAACAGGGCTAAAGATACCATCCTTAGTAGTGAAGACATTTCAGTCGGTTCGGATATTATCAGTATCTCTGACATTGCTCCCTCTGCTGTAATTTCCGAGTCTGTATCCCTATATCTTTCCAGCACTATTACTCCCGGTAGTTACTATCTCCTATACCAAGCTGATGGTTTTGGGTCATTGAGAGAAAGCAATGAAAATAACAACGTCGTTGCCAAAGCAATTACAATTACTGCACCAGACTTAGTAATAGTAGATACTTCAGTTCCAACTAGCGCCGCCATTGGTACTACACTTGAATTTACCTATAAGATCAAAAATCAAGGTAATGGCAATGCTGGTAGCAGCAAAACAGCTTATTCTCTTTCCAGAGACACAATTTTAGGCAATGATGATGATATATCGATAGGGTACGACACTGTTCCCATTCCAAGCCTGGCACCCTCTGCTATATTTTCAAAGTCCATATCTTGGACTATTGACACCACCATTGCAGCAGGTAAATACTATTTGATGTTCAAAGCCGATGGATTGGGAGATGTTGCCGAAAGCAATGAAAGTAACAACTCGGTTTACCATACACAAGCAATTAGTCTCACTCCGATTAATGGTGGCGGGTTTAACTCAACTACAGGTTATGGCTTAATTAATGCTGCCGCCGCCGTAGCAAAAGCTTTAGGTCAGAGTACCTTTGCTGATGTTCCTGACTTGGGTGGTGATAACTGGGGAGCTGACTTAGTGAAAGCACCGGAAGTCTGGGCTAAGGGATACACAGGTCAGGGTGTGATCGTCGCTGTGATAGATAGTGGAGTAGATTACAATCACTCAGATTTGAGCGCTAATATCTGGAAGAATACCAAGGAAATCGCTGGCAACGGCAAAGATGATGATGGCAATGGTTACATTGATGATGTCAACGGCTGGAACTTTGTCAGCAACAACAACAATCCATTAGACGACAACGGTCATGGTACTCATGTTGCTGGCACTATTGCTGGGGTGAAAAATAACTTTGGTGTCACTGGTATTGCCTATAATGCCAAGATTATGCCAGTGAAAGGTATGAATAGCGATGGTCAAGGAACTAATAGTGCGATCGCAAATGGTATTCGTTATGCAGTCAATAACGGAGCTAATGTCATTAACCTCAGCTTAGGTGGTTCTGCAAGTAGTGAGATACAGTCAGCTATTCAATATGCTGCCAGCAAAGGCGCAATTACCGTCATGGCAGCAGGTAATGATGGTAAATCAGAACCAGACTATCCCGCCCGCTATGCTACCCAGTGGGGGCTTGCGGTTGGAGCAGTCTCTTATAATGGCGTACTGGCTGACTTCTCCAACCGAGCTGGAACAACTCCACTTGCATACGTTACAGCTCCAGGAGTCGATATTTACTCGACACTTCCAGGTAATAATTATGATTTCAAAGATGGTACTTCTATGGCAACTCCTAATGTTGCTGGGGTAATAGCTTTGATGCTCAGTGCTAAAAAAGGTTTAACTGATGCCCAAGTGCGTCAGATTGTCACAACGACAGCAGCAAATAGCTTGGCATAGAATCATCCCTTAAGTGTCGTTTATCAAAGGTAAAATGCAATTTCTATAAGCGGCAGAATGAGCAGCAAATGCCACTCATTCTGCCGCTTTTTTTATAATAAAGCGTATTCTAAATAGCTATTCACAAAAAGCATGATTCTCATAATATTTTTTTGGTAATAGAATTAGCATTTTATTATTAAATTTCATAGTAATTATTAACAATACGGCTTATTCACACGTTAGAACTTTTGTTTAACAAAAGTTCTAATAATTTTAGCTGTTAAAAAGCATTTCTATTTTTGAGAAAAAACAATTATGTTCAATGATAATACTAATAACAATTTATTTTCTACTAATAAAAGCTTAAATTTTACTTCAATCTCTTCATTAGATACATTTAATACTAAGAATGACACCAGCTTCAACTTAAGCGGACGTAGTAGCTACAACTCAGCCGATTCTCATGTGCAGTTACTAAATAATAGTAACTACGAAAATAGCAGTAACGCTACTACTAATGCTTTTACCACGCAAAGTTATAACTCCAACAATGGCTATGGCTTAATTAATGCAGCAGCAGCAGTGGCTAAAGCTACTAATCAGAATACCTTTGCTGATGTTCCCGATCTTGGTGGTAATAATTGGGGAGCAGACCTTGTAAAAGCACCAGAAGTTTGGGCACAAGGATACACAGGTAAAGGCGTTGTTGTCGCTGTTATAGATACTGGGGTTGACTATAACCACGAGGATTTAAAAAATAATATCTGGACAAATACCAAGGAAATTGCAGGTAACGGTATAGATGATGATGGCAATGGCTATATTGATGATAATTACGGGTGGAACTTTGCGGATCAAAACAACAACACACTAGATAACAATGGTCACGGTACTCATGTTTCTGGCACGATCGCAGGAGAAAATAATAACTATGGTGTCACTGGTATTGCATACAATGCCAAGATTATGCCTGTCAAAGTTTTGAATGAGTCTGGCTCTGGTTCCTATAGCTCGATATCTAAGGGTATTCGCTACGCTGTGGATAATGGAGCGAATGTGATTAACCTCAGTTTAGGAGGCACATCTTCCAATCGGACTCTGGAGTCAGCCATTAACTATGCCACTAGCAAAGGAGTGATTGTTGTCATGGCAGCAGGTAATGATGGTGAATCAGAACCAGACTATCCTGCCCGCTATGCCTCCAAGTCGGGAATTGCTGTTGGGGCAGTAGACAAAAATAATAATATGGCTGATTTCTCTAACCGCTCTGGAACAAATCAAATTTCTTATGTCACAGCCCCAGGAGTCAAGGTTTATTCATCAGTTCCGAATAATCAGTATGCCACTTATAGCGGCACATCTATGGCTACTCCCCATGTGGCTGGTGTAGTTGCCCTGATGCTTAGTGCTAACCCCAGCCTGACTGATGCCCAAGTACGTCAGATTGTGGCAGAAACATCAGAAAACAGCACACAAAGTACAAACTCTAGTTTAAATATTTCTAATGTTAGTTCTTTGGCAAAGCAAGTGATTTCTACGACGGGCTACGCAGACACAGCAGCAAATAGTTCACAAATTACAACCTCTAGTTTAAATATTTCTAATATCAGTTCTCTGGCAAAGCAAGTGATATCTGGCAACAACCTGCTACATATCGATGCACAAACCAAAAATTATCTCACACCAGAGACTATTGCTAGTTTTAATAATTCAGATGTCGCTTCTCTAATCGGTCAGACTATTACAAAAACAGCAAAATATCTCACACCAGAGACTATTACTAGTTTTAATAATTCTGATGTTGGTTCTCTAATTGGTCAGACTGTTACGGAAACAGCAAAATATCTCACACCAGAGACTATTGCTAGTTTGAATAATTCTGATGTTGGTTCTCTAATTGGTCAGACTGTTACGGAAACAGCAAAATATCTCACACCAGAGACTATTGCTAGTTTGAATAATTCTGATGTTGGTTCTCTAATTGGTCAGGCAATTACAGAAACACCAAAATATCTCACACCAGAGACTATTGCTATTCTTAATAATTCTGATGTCGCTTCTCTAATCGGTCAGATTATTACAGGCATCAATACGGATAGCAATGATGATAACAAAAATGAGAATAATCTTGATTTTTGGAAACTACTAGAAGGGATGCAAAAACAAATGGATCAGTATAAAAAATTCTTAGGTATCGCTTAAAAATTATAGCGATTTGTAGTTCAGTCAAATACTGCTCGGTTAGAAAAATAAACCAAACCGCTCGTCTGTTACAAATAAATTTAAGGGTTTAGCAATGCTAAACCCTTACGTTTTAGGTGTGGCTTGTGGAATGCGTAGGCATTGTTTTTGAAATAGCTATAAGAACAAGAGAGGCTATCAATCTACCTAACAGAAAATGCTTCATTGAACCGCCGCGTCACAGGCTCAGTGATGAATGTCAGAATTGACTTTTTACGAGTGACAATTTCACCTGTAGCAGACATTCCTGGTGTAAATTCTACCTCTTGACCACGCACATTAACTGAATGTTTATTTAGCTTAATTCTTGTAGGAAAAACTAAGCCCAATTCTTTATCAATAATTGCATTCGGACTGACTTGCATAACTTCGCCCTCCACAACACCAAATTCCTGGAAGGGGAAAGTCGCCATTTTCACTTTTGCTTTCATTCCTTGACGAATAAATCCAATATCGCGGTTAAGAACTTTCACCTCTAGGAGCATTTCTTCCCCTTCTGGCAAAATTGACAGCAATTCTTCACCAGATTGGACTGGCCCCTTGGTAGCTTTGACTCTGTAAATCGTACCTGCAACGGGAGCCTCAATCGTTTCTAAAGCTTGCTGCTTCCTCGCCTGCTCTAATTGACCTTGAACAGTTGTCAGTTCTTCTTTACGTTTGTTGAACTGGGTTAAAATTTCACTTTGGCGTTCTGATGCGACACGCTGGGCCTGACTGCGGGCAGAGTTGTAAGCTTGTTCTGCTTGGCGAATTTCTTGGGCTTGAGCAGCAATATCTTTTTCTAATGATGTGACTTTATCTTGAGCCTCTGTTATTCTATTCTGGGCGTTAGTCACTTCATCTTGCGATCTGGTAATTTCTGTCTTTGCACGAGTCAATCTTTCTTGAGCATCCAAGTAATCGACACGAGGTACAGCACCAGTAGTAATTAGGGTGCGTAAGCTTTTTTCCCTTTCTTGTGCAAGTGCCAAATTACTTTCAATTTTAATGCGGATGCTGTCTGCGTTGGCAAGGTTGGTTTTGGCATTAGCAAAGCTGCTTTTGGCATTAGCTAAGTTCTCTTGCAATCGAGTCAAGCGGACTTTGGCTTGATTGATGAGTGCTATTTGGCGATTTGCTTCTGCTTCTGCACCTGCTTGACGTGCTTGGTAGTCTTGCAGGCGGGAAGTTAAAAGTTCATCTTGTAGTTTCGTCCCAGTGGTTTTGCCTCCAAGACGTTCTGCATCCAAACGTTGCAAATCGTCTTGAATCAATCTAGTTGATTTGGCTAGGCGGGAAACATCAGTTATTTGTAAGTCAGGGTCTTTTTGAATCAGAATTTGACCTTTGGTAACGCGATCGCCTTCTTGCACTTTCACGCCGACAATTGACCCCCCACCCAAGGATGTCACTGGCCTAACCTGTGTAGAAGCAATTAATTCCCCTGGCGCTGTTGCTACTTCATCTATTTGCGAGAAGTACGCCCAAGCGATCGCTCCAAATACAATGGCGCTCATCGTTCCCGCTAATAATCTCGTATACAGGGGTGGTAATTCCTGTACCGCCTTCCCCAATTCATAAGTGAGTTGTTCCTCTGGTTGGGCGAATCGCTCTTTTGTCTGACGTGCTTGAGCAGCATTTACCATATATTTTTATCCTTTTTTATTTGTCATTAGTCATTTGTCCTCTGTCCTTGGTGATTGACTAATGACCAATGACCAATGACCAATGACCAATGACTAATGACTAATGACTTGTGTTTAATTCAAACTGCTAGATAACGCCGCAAAAAGTTTTCTAATGTCTCCAATTTGAAGTTAAAAATCGCTTCTAAATTGGCAATTTCATCTTTTGTACAGAAAAATTCATTTGCTAGCAATGTGCGATAAGTTCCCAAAGCTTTTTGGACTTGGGGATTAAATAAACCCAATGCACCTTGTAATCCATCAATAAAAAATAGTGGTGAATTAATTATTACTGGCTCTTTGGCGAAAATCCGACCAAAAATCCGGGGAATATCTTCTCGTAATAAAATCTCTGGGCCTCCCACTGGTAAAATCTGGTTACGAGCGCCTTCAACTGTCACAGAATCCACTACTATCCTTGCCAAATCATCGGTACTGACAATTGAGCTACGGTTTTTGCGATCGCCAATCAGCAGATACAATCCCGTTTCCCGAAATCGTTCTACCAGTGGCAGCAAGTTAGATGCTAATCCAGATGGGCGTAAAATTGTGTAATTCAAGCCACTAGCTGACAAATATCGCTCTACGGCTCGTTTGGCTTTGAACACAGGCGCGTCTTCATATCCGCGATCGGCTCCCAATACCGAAATGAAGACAAAATGCTCTATGCCATTGGCTTTTGCTTGGTCAATCAATTCAATATTGGCGCGGTAATCTAAGGATAAAGCATCGCTATCAGAACCGTGAGCGCTGATAATATACTTCACACCTTGAGTAGCTTTTTGAATATCTTTTTCTCGCAGCAAATCACCGATAAAGATTTCTGCACCCCGGTGTTCTAACTCGCTGTAGCGCGAGGTAAGGCGAACAAATGCCCGCACAGACTGTTCTCGTTGCCGTAGCAGTCGCACAACTCTGCGACCAATTCCTCCAGTTGCTCCAGTTACTAGAAACATATAAATACCTAAATTGAATAGTTGCAGCGTTTATAGTTGTCAAAATGCCCGATATATGGTCAAGATATCCTCACGCCAACTAAGCCAATTGGTCACACCTTATTTATCTTAATCTCAAAAAATTATCCCCCACATCTTTGTTGATGCAGGGGATGGGGTAATGGGATTAGTTTTACTGGCTCAAGAAGTCGATAGCTTGTTCAAGCGACATCTTAGCTTTGTGCAAGTTCAGCAAATTCTCTTGCTGATATCGGTCAGGATAGCTCATTTTTCTGCCTTCCAAAGTTATCCGAATCAGTGCTGTTTGTTCGTCTGTGGGTGAATTCATCTCCTCAATTGCAGAACTGATTACCTGGATAGCGTTAAAGTTAGGGGATTTTAACCCTTTACCTAGCTTCATTTGTTGGAGGGCTAAAAGTGGAAATGCCATCAGAGTTACGATATACGAGGTTTTGTATCCTGCATTCCCGGTAGGTTTTACACCGTATCTCCGACATAAATCGAGTAATTCTTTAATAGTCTTGATTTCAAGTTCGGAACGCGTGAACATAAAATAGTAGTATCCATTTTTTGAATTGGATATTGGTGGTTGTACTTCCGGCAAGTTGTTACAACCACTAAAAAAAAATTAATCTGCTGCCTACCAGTGATTCAAATTATATTTATATTTCTACATAAATGCCTAACCCTAAAGGTCATTCAGAAAATTTAAAACCATTTAAATCAGAGAGGGAAGAACCTTTAAGTGAACGTCTTAATTTACGTGTCACAAAAACTATGAAGGAAGAACTATCTACCAAAGATGATCCTCCAGAATTTTGTCGTCGTGCAATCCAAGAAGCATTAGATAAAGATAGAGAAAAGTAATCTCAAAGGGATAGTTGTCACGAATGCGTGAATTACTGCAATGAGTCAGCAATCAAGCATATTGAGAAAGTAATATGCTTGATTGCTTGCGGAAAACACCGAAATTAGAAAGCAAACTGGGGTTTGAGAAAGTAAAAGCTTCTTTTGAGTAAGTCAAATGCCATTTTGTTTATTAAATTGGACGTAATTACTTAAATTACGTTAAGAAGATTTGTAGGTTGGGTTGAACGGAGTGAAACCCAACAAAGCCGTGAAAATGTTGGGTTTTGTTCCTCAACCCAACCTACATTAAAGTTATTTTTTAGGCAAAACCTCGCAGTATTTATCTGAGTTAAAATCGTTTAAGAAGGATTTAAAGCAGTAAGTATAATGTATTAGCAATTATTGCCGATATAGAGAAGTGGATGTGAGGAGACTTATAGATGAGTGACGAAAATCAGTTTGATGTCTTCCTTTGCCACAATAGCAAAGACAAACCTGAAGTTATAGAAATTGCTAATGAATTAACAAGACAAGGAATTAAACCTTGGCTAGATAAATGGGAACTTCGTCCTGGTTTAGGATGGCAGGTTTTACTAGAAGAACAAATAGAAAATATTAAATCAGCAGCAGTTTTTGTAGGTAGCAGTGGACTTGGCCCCTGGCAAAGTCAAGAGATGAGAGCTTTTTTAAACGAATTTGTAGAAAGAAAATGTCCCGTAATTCCCGTTTTGCTTGGGAATACACCACATCAGCCTAAACTCCCAATTTTTCTTAGGGGTAATACCTGGGTTGACTTTCGGACAGATACTGAGGCTATGGAGCAGTTAATTTGGGGTATTACTGGACGAAAACCAAAGCTACAGCAAGTAATTCAAGTTGATAATCTCAGTTCTGAGAAGGGAGTAAACTACACGCGATTGCGAGATTTGCTAGCAGCAGGCAAATGGAAAGAAGCGGATGAGGAAACTTTAGCTGTCATGCTCAAGGCATCTAGCAGGGAAAAAGAAGGTTGGTTTGATATTGAATCCATCAAGAATTTTCCCTGTACTGACTTACGCACCATTGACCAACTTTGGGTACAACATAGCGATGGGCGCTTTGGCTTCAGCGTTCAGAAGAATATTTATCTAAGTGTTGGTGGGAAGGCTGACGGTGAATATTATAAAGAAGTCTGGGAAAAATTTGGCGATCACGTAGGATGGAAAGTGAAAGGAAGCTGGATTGATTACTCTAGTGTAGATTTTAATATTTCAGCACCAGAGGGACACCTCCCAAGGATGAGTGGGGAGGGATATTTATTATTTGGGATTGGTGGTGTTGGGAGGATATCTTTTCTCGCCTCAAGACTTGTGAAGTGTAACATTTAAGAGCTTGAGAAAAGTTTTCCCAATTTAAAATCCCCCCACATCTGTGTAGATGCAGAGGGACTAATAAAACAACCCACAATTTGGATTATTGATCAATTTTTGAGCGCTATCGGTGACGTACTATTATACTTTGTGCAAACAGCCCATTTCAAAACTATTCAGCAGCTTTGTTATTAGCTCTATTAGCACGCGCCTCAGCCGAAGCCATCACCTCATCCATATTCTCTAGCACTTCACCAGGGAAGTTTTCCAAAACTCTGGTAGAAAGAGCAACCCGTCCTTTACCTTCATCCAAGTCAATAATTACAGCCTTAATTGGCTGACCAACTTTAAATACCTTTTCTAGAGAATCAATGAATTTTTGGCTTACCTGCTTGATATGAAGCAAAGCCCCCATACCATTTAAATCGACAAACACACCAAAAGGTTTGATGCCAGTAACTTTACCTTCCACCAGTTGACCTAGTTCTAATAAGCTGAAGTTGCTAGAACGAGTTGCTAATCGCTGAGAAAGGATGAGTTTGTTGGTGTTTTTATTAATTTCCAAAAAGCCCACAGTCAGATTTTGACCTTTAAGTGCGTCTAAGTTATCACGCTCTGCCAGGTGCGATCGCGGAATAAATCCCCGCAAAGAGAGAATATCGACGGTAACACCACCTTTATTCACACCCATAACCTTTACTTGCACAGTCTGAGCATTTTCCTGCATTTCCGCCAATCGTTCCCAGATGTGCTGGATTTCCAACTGCTTTCGAGAAAGGGTGACTTGACCTTCTGCATCCTGATCTCGGATAATCAAAAACTGCATTTCCTCTTGCAATGGCAGCACTTCCGATAAATCGGTAACTGCTCTCAAAGAAGCCTCATCGCGCGGTAGAAAAGCTGACGACTTGCCACCAATATCGACATAAGCTCCATCATGGTCAAGTTGGAACACTTTGCCATGTACAACCTGTCCTTTTTGAAACTGGTAGTCGTGTTTTTCTAGCGCTTTGGCAAAATCGTCCATCGTAAATGACGAATTGGCTGTTTGAGAAAGTTTCGATTCGGAATTCATGACTTTTGAAGATTAATTGTTATTTGAGATGGTGCAACTGGAGTTTTGATTGTCATTAGTCACTTGTCATTTGTCATTTGTTCTTTATTGTTCACTAATGACTAATGACTAGTTCAGTTGACTAAAGAGTTGTTTGGCTTGCTCCCAAGCATCAGCAGCAGCTTTAGGATTATAACTGGCACGAAGGTCACAGAAAAATCCGTGATCAGCTCCATCGTAGCGAAACACACGATGAGGAATTTTATATTTTTCTAACTCTGCTTCAATCTCATCTACTTGTTCGGGTGGGATGCTAGCATCTTCTTTACCAAAGAAGGCATAGAGAGTGCCTGGAATCTCTCTGGTGCGGGTAACAGTGGGTGCGCCACCTCCTGGCGTGCGAGTGGTAATTCCAGCACCGTAGAAGGAAGCCGTAGCTTTAATATCTGGTAAAGTGGCTGCAAGATATGCAACATGACCGCCAAAGCAGAAGCCAATACAACCAAAACTATCTTTTTTGACTTGAGGCAGATTTTTGAGGTAGTCAATTGCTAATTGAATATCGCTCAATAACTCTGATGCTTGAGTTTGCATAGCGTAGCCTCTGCCCGTTTCAATATCTTCGGGTGTGTATCCGGTTTCAAAGCCAGGAGCAGTGCGTTGAAAAAGTGCAGGTGCGATCGCTACATACCCAAGTTTGGCAATCCGTTCTGTAACATCCCGAATGTGAACGTTGACACCAAAAATCTCTTGCAATACAACGATTCCTGGGTAAGATCCAGGTTCTTTTGGTTCTGCCAGATATGCTGACACTTGAATATTATCTTGCAAAAGATTAACCGTTGTGGTAATTATTGCTTGCTCTGCCATAATAATTTTTACCCGTGTTATGTGATTAACGGTGTGTTTGTTTGATATAACTATGCCAGTATGCTGAGGTTATTTCCAATAGAATTACCAAATACCATAGTGAGCGCATTAAAAATTTCTACCAGAAAAATTTTATTTGTAAATCAAATATTTTGATATGTAGCAAATACAGCTGGTCACTAAAGGAGTGCTATGTATAGAAGTAACACTTAATACCCAAAAATCAGCACTTATCACTCAGCACTTAGTATTCAGGAGGTTTGGTGGTGATTCAATTCCGTATTCAGCCAGACAGCGAAATTCCCGCATCAACCCAGCTGTTTAATCAAATCCGCTTTGCGATCGCTTCGCGGCAATATCCCCCTGCTTACAAATTGCCAAGCACAAGAGCGCTGGCAATGCAAACGGGATTACACCGTAATACCATTAGCAAAGTTTACCGTCAACTGGAGGAAGACGGATTTGTTGAAAGTATGGCTGGTTCGGGTATTTATGTTCGTGCCCAAGGTCATGAGGGCGGTAGTCGGCTGCAATCACCAATTCTCAAACAAAATCCTGACGCATATCAAGTTGTCCAGCAAGCACTTGACGATTTGCTCTCTCAAGGATGTTCGCTCAATCAAGCCAGAGAGCTATTTTTAGCGGAAATTGACTGGCGCTTGCGTTGTAGTGCGCGGGTACTAGTTGCAGTTCCATCCTATGACATGGGTGCTGGTGAGTTGATGGTCTATGAATTAGAGCGATCGCTAAAAATTCCAGTCCAGTTAGTAGCAATGGAAGAATTAACAGCAGTGTTAGATAAAACTACCTCTGCAACAGTAGTCACAAGTCGGTATTTTATCAGTAATGTGGAAGCGATCGCAGCTCCTAAAGCTGCACGGGTAATTCCTCTAGATATCTACGACTACAGCAAAGAACTCAGCCTCTTAAAAACCTTACCAAAAGAAAACTGTGTAGGCATAGTTAGCCTCAGTTCCGGGATTGCACGAGCAGCAGAAGTCATCCTCCACGGTTTGCGGGGAGATGAACTACTAGTGATGACTTCGCAACCAAAAGATGCCTATAAACTTCAGGCTATGGTTAAACGGGCTGAGGTCATCATCAGCGATCAAGCCAGTTTTGCAGCAGTGCAAGCAGCCGTACAAGCATCTGATGAAGATATTATTCGTCCCCCAAAGCTGATTAAGGTTGAAAATTATATCGGTACTAACTCGATTAACTTGCTCAAACGAGAACTAGGTTTGAGTTAATTACGACTTACGTAAAATACTCTCAAACTCTCATTTCTCTGTGTTCTCTGCGCCTCTGTGGTTCGTTATTCTGGAACTAGTGCAGAACACCTTTGAGAACAACCAATACAGGAGGGCTAAGGTAGTGCAGATTGTGATTGTAGGCGCAGGCCCAACAGGTGTAACCCTTGCCCTGCTCCTTACACAACGTGGTATTGCTGTAACCTTAATTGAAGCAGCAAAAGACTTTCATCGTGTTTTTCGCGGCGAAGGATTAATGCCCAGTGGATTAGATGCACTAGAGCAAATGGGTCTATCGCCATTGTTAGAGCATATTCCCCACCGACAACTCGACGCATGGGAATTCATTGTGGGGGACAAGCAATTGTTTCGAGTCGAAGAACCAATGGGGGCAACCCGACCTTGTACACTGGTTTCACAACCACCGCTACTCAAAGCACTGATTTCGGAAGCTCAAACCAATGATGGGTTTGAATTTATCCAGGGTGTTCCAGTCAAAGATTTACGTTGGAGTAATCAACGTGTCGCAGGTGTAGTATTGAGCGATGGGAGAGAACTAACTGCTGACCTAGTAATTGGGGCAGATGGTCGAAATTCTCTTGTGCGGCAACGTATAGGATTGGAATTGGTACGCCAGCCCAAAAATATTGATATTCTCTGGTTTAAACTTGCCGCCAGCCCTGAATTTGCAGCCGATAATGTTTTTCGTACTATTGTAAATGGCGATCGCGTATTTACCATCTTTCACGGAGCAGAATCAGGAAAACTGCATCTAGCTTGGGTGATGTCCGCAACCGAAAACACTGACTTCAAGCAAGCTAACTGGGCAGAGACTTTTGCTTCATTATCACCCTCATGGCTAGCAGAACATTTCCGTAATCATGCAGACACCATTGAATCCCCGATTCGGCTTTCTGTTGTAGTTGGTTATTGTCCACAATGGCACGCACCAGGGGTACTACTTCTGGGTGACGCGGCACACCCAATGTCTCCTGTCCGCGCTCAAGGAATTAATTTAGCATTGCGTGATGTCATTGTCGCTGCTAATCACCTTGTGCCACTGTTGCACAAAGAAGCCGAACACAAGGACATTGATATGGCACTATCGCACATCCAAGCAGAACGTGAGCCAGAAATTATCCGCGCCCAGCAACTCCAGTTACAGGAAGCTAAACAAGGCGAACTACTGCGAAAAAATGCACTGTTGCGATCGCTGTTGAGTCAACTCGCTCCCTTGCTCCGTAAAATAATTAAAAAGTCTTGGTTAAAGCGACAATATAAAATGCGTCAAGGTATCACACAGGTTCATTTAACTGTGTAAAAAACCGCCAGAAGTTATTTAACTTGTGGCTGTGGAATATTAATTTGCAAAAATTCTTGCACCACTTGCATATAAGTTGGAGCATCTTCCAACATTGGGAAATGTGCTGTGTTAGGAATCATCACAAACTTAACTTTGTCATTCAGTCCAGCTGCTTTACGCCCCATCTCGGCTGGGATAATTTTGTCATACTCTCCCGCCACGAGCAGAGTCGGTACTGTCAGCTTGGCAAACTCAAGCGGCATCACTTCAGATTGAGCTTTACTAACGGAAGTAAAAATTGTACCCAAAGCTGCATCGTAATCTGCTTCAAGAAAATCTTGTAAAAAAGCTTGGCGTTCAGAATGTGGTATTGAACTATATAAAAATCTCGCCATAAACATCCGGTCAACAAATGGAATTTTGCTTAACCATTTGGGACGGAATTTCACCACATAGCCACCGAATTTATGAAAGGCACTAAAAGATTTTTCGTCGTACTCAAAAATGCCGCTACAGGTTAAAATTCCTCGTTCCACTCGTTGGGGGTAGCGGTTAAAAAATAAAGTAGCAACAGACGCGCCCATCGAGTGAGCATTGATATAGACACGCTGAAGATGCAGCCCATCTAACAAAGCTGCCAAATCATCAGCGTATTCTTCTAATTCATAACTTAACTCTCTGATTGCCTCTGATTCTTCCTGCGGGGACTTAGAGTCAGCAACAGCTTCACTTGCTTGACCTATGGTTGGCTTACCACCAGAACGGCCAAATCCCCGCATATCGTAGAGTAAACAATCAAATTGCTCTGATAAAGCATTAGCGGTATTTTGCCAATACCTAGCCGAACCAGCCCAACCGTGCATAAAAACCATTACTGGTTTTACCAAAGAACCAGATGGTTTTTTCACCCATTCATAGTAGTGGTCAACGCCACGAACTTTAATATAAGGCATTAGTCATTAGTCCTTTGTCAGTTGTCATTAGTCATTTTCCCTTATTACATGGTTATTAGTCTTTAGTTTTTGACTAATAACCAATGACTAATGACTAATGACTAATGACTATTAGGCTGACTCTGGTTTCGGTAGTGAAGATGGATGGATTATCAGTTCCGCAGTTGATCGCTTCTCGACCATTTCCCGTGTTACTGTACAACGTGTCACATCCTTACGGGATGGTAACTCGTACATTACATCCAGCATAAGTTCTTCGACAATGCCCCGTAGCGCTCTTGCACCAGTTTTACGGCGGTAGGCTTCTTGAGCGATCGCTCGTAAAGCATCTGGTTTAAAATCTAACTGGACATTATCCATCTTCAGCAGTTTTTGGTACTGCTTCACTAAGGCGCTGCGTGGCTGGGTGAGAATCGCCATTAGCGCTTCTTCATCTAGCGGATCTACTACTGCTACCATTGGCACGCGTCCAATAAATTCTGGAATCATGCCAAATTTTACTAGATCGTCCGGCGCTAGATGGCGGAGAGTATCTGCTGCCCGCTTTTCTTTCGTTTGGCCTTCTCCAGGTTGCACAAAGCCTATTGCTTTTTTGCCAACTCTCTGATCTACAACCTTTTCTAAGCCTACGAAAGCACCACCACAGACAAACAAAATATTACTTGTATCAATTTGGATACAGTCTTGATAGGGATGCTTGCGCCCTCCTTGGGGTGGTACATTGGCGATCGTTCCCTCTAACATTTTCAACAAGGCTTGCTGCACGCCTTCGCCAGAAACGTCGCGGGTAATTGACGGGTTCTCACTCTTACGAGCAATTTTGTCAATTTCATCAATGTAGATAATTCCTCGTTGCGCTTCCTCTATATCCAAATCTGCCACTTGCAACAGTCGCAGCAAGATATTTTCCACATCTTCTCCCACATAACCTGCTTCCGTCAGCGTCGTAGCATCGGCGACGGCAAAAGGTACATCCAGGATTTTCGCTAAGGTTTGCGCTAAGAGAGTTTTGCCGCAACCAGTTGGGCCGATTAACAAAATGTTGGACTTTTGCAGTTCTACAGCATCATCCGCCCCACCTTTGCCACTGGCTTTAGACTGAATGACTGCCAACCGCTTGTAGTGATTGTAAACGGCTACTGACAGGACTTTCTTGGCTTCGTCTTGACCAATAACGTGTTCGTCTAGATACTTTTTAATCTCTCTTGGCTTGGGTATTTGATTAAACGAAATACTAGAAGATTGAGTACGCCGTTTTTGAGGTGGTTCTGCTCTTGGTGCGGGTTGTGCTGCCGCACCATTGGTATCGAGTAACTCTTCGTCTAGTATTTCATTACACAAGTCAACGCATTCATCGCAGATGTAGACTCCCGGCCCTGCGATTAATTTACGCACCTGCTCCTGAGACTTGCCGCAAAACGAACATTTTAAATGGGAGTCGTACTTAGACATACCAGCCTCTTATTTCAGAATGGTGACGTTTTCCCCTGCTGTGGGAAGATTTTGCCTGGAAATGACCTGATCAATCAAACCGTAGTTTTTCGCCTCTTCTGCCGACATGAAAAAGTCGCGCTCAGTATCTGCTTCAATTCTTTCTAAGGGTTGACCAGTATGATGAGCCATTAACTGATTCAACTTAGCCTTAACGTAAAGAATTTCTCTGGCTTGAATTTCAATGTCAATAGCTTGACCTTGAGCGCCACCAAGTGGTTGGTGAATCATAATCCGGGAGTCAGGCAGAGACATTCGCTTACCGGCAGCCCCTGCTGTTAACAAAAATGCCCCCATACTCGCGGCTAATCCAAAACAGATGGTAACAACATCAGGGCGAATTTGCTGTATTGTATCATAGATTGCCATCCCTGCGTAGACCGAGCCACCAGGAGAATTGACATACATTTGAATGTCTTTCTCTGAGTCTTCGGAATCTAGGAATAACAATTGAGCCACAATTGAGTTGGCTACGGCATCGTCTATTGGCGTTCCCAAAAAGATAATCCGCTCTCGCAGCAGGCGGGAGTAGATGTCGAAAGCCCTTTCTCCCATGCCAGACTGTTCTACCACCATCGGCACGATGTTGCTAGGGCTGTTCAACTGGGAGTTAATGTTTATTCGACTTTGGTTGCTGATGGGGTAGTTTCCCGACTGCGATACAAACATACAGGCTTTCTATGACGGTAATTTAGGACAAATGTTTCAGCAGCAAATACTGCCTTTTCGACGAATCGAATTTTTATAGCTACGTGTTAACCATTATGCCTCATATAACTTCCTCTCGTGTAACACAGTATCAAGCTCAGTCCATAACATGTGTCACAATTTGCCAAAAATTCATTAATTCTTTAAATTATTTTGACTTTATCCCAGTGGGTATTGGGGATTGGTTATTTTTGTCCCTGTTCCCTTACCTTACCCATTTCACCAGTACTTTAACTCAGGACTGGTGAACTTATGGCTTTGGGATTTTTTATTATCCTTCTGTGACTTCTGTTGTAGAAGGTTCGCTGTTTTCTTCCTCTGTCTGAGATACATCAGCATCAGATTCTGCGCCTTCCGTTTCCTCAGAGGGACTCAAGGAGCCTTCGGGTACAAGTTCAACTGAGGAATGTTCTAAGAGCCAATCGATGGTTTTTTCGGTTAATAGTTCGTTTTCCACGATGGAGCGCAGTCTATCTTCATCAACCTCTTTTTCTTCTGGGTACTGTTCCAAAAGTTCTTTGACTCTGGCTGCGATTTCTTCTGGTGTTACCTCAATAGATTCGCGTTTACCGACTTCCCGCAAGGACAAAGAACGTTTGATGCGTTCGATGGCCTCAGTACGCGATCGCTCCCGCAATTGAGGAATAATATCTTGAGTAAACAACTTCCTCACATCTAATCCCTGCTGAGACAGGCGCATTGCTGTTTGCGTTAGCATTGCATCCACTTCTTGCTCAACTAAGGTTAGTGGTAAGTCGACTTCTACGTGCTTGAGCAGTTCCGTTAACAAGGCTTCCTGCTTATTTGTTTTTGTTTTGTCATCCGCCTCTTTTTGATATCGCTCTACCAAAGAAGCGCGTAACTCCTCTAAAGTTTCAAAATCGCTGATTTCCTGGGCGAAATCGTCATTTATCTCTGGTAGTTCCTTTTCCTTCAGTTCTTTGAGCGTCACTGTGAAAGTAGCTGCTTTTCCAGCTAAATCCTCATTAGCATAAGGATCTGGGAACTGAGCCGCGATTTCTCTAGTTTCTTCAGGATTCATCCCTACTATTCCCGATATAAAGCCTGGGATAAACTTATCTTCCTGCAATTCAACTTGAAAATCAGTTGCTTCGGCTCCCGGAATAGGTTCTAGTTCGGCTGTTTCGTCTTCACCCTCGGCTTTAGCAAATGAGCCTTTAAAATCGACTACGGCAATATCACCGATTTGGGCTGAACGTCCTTCCACAGGAATTAATGTCGCTAATTCTTGACGTTCCTTCTCAAGGGTACTATCCACTCGTTCTGGATCGTACTTGACTTCTTCGGCTTGGAAAAGCAAATCAGTGTACTGCACTAGATTTACTTCTGGTTCTACATCGACAGCGGCCGAAATCGTCAGAGGTTTTCCAGGTTCATAATTATTAATCAAATCCTCAAATGAGGAGCGCAATTGCGGCTGACCGATTGCCGGGATAGCTTCTTGTTTAACTGCTTGCTCAATGCCGTCTTGAATTAGTTCTTCCAGCGCTGCTGCCTTGATACGAGTTGTACCCAGCCTTTGTAGTAATATCGGCCGAGGTACCTTGCCTTTACGAAACCCAGGAATATTGGCAGTACTCGCTAAGTTTTTAATGACCTGTTCGTAAGTTTGCTTGGTAATTTCCGGCGTAATCTCTATTTCCAGGCCAATTTGGCTGGCGGGAAGTTTTTCCTGGGTAACTTTCATGCTTCGTCTCTAGTTTTCTGGTATTTTAATCTCCGAGTACACACAAGACGCAATAATTTTTCGCGTTTATGGCTTGATGTCTCTTAGGGAGGAGGGGGAGTTTGTCACAAGGCTTTATGACATCCAAGGATGGATTGTGTGTCTTGGCACAGAGATCCAGTTTACTGCCAATGGCCAAGGACTTGACAATTTACCGTCATAACAATTATTGACACTCCCAGGGCTAAGAACGTCTGGGGTTTCTTGCCTAATATTTGTAATAAGCGCTGAATCATTGCGGATTGGGAAGATTTTTATCCTTATTCCCCAGTCCGTAATTTTCAGTTAGTCTGAATTTAGCACTGGAAAGTCAAGAATTCATTATTCGGTGGGCTAAGACCGTGATATTCTGATTTTCAGTCAGTAGTTTATTACTTCAAAGTTATAGCATTGAGTCTAGCTATATTTTGGTACAGGATTAAACAGGCTGCCTAGCCGCATAGCTCGATTTTATCGGTTGCGAATTTTATACCATTTGCATCATAGTACATTCATCGTGCTGGCAACTCACTTTACAGCCAAGACGTTTATTCACCTTACAGGTCAAATGTCTAAGTGCAGATATATGTATTTTTCTGCTAGATGGCGCTTTGTTGTACAATAATATAATATAGTTTTAGATAAATGAATAAAGTTAGATGGCGGTTGTTGTCAAATGCAACATCACTTAACTTATTAAATAACCCAAGTAAATAAATTTATTAAATCTACTAAAGATAGACTAAATTAGAGAAAATCTCAATCTATTCAAAATTCATTTCAAGACTGCGCTCGCTATTTAAATATAAATAAATTGTCAATTGTTCCAAAAAATTGCAGATAAGTCTCTTAAAGGAGGAAGCAAGTTTGTCGAAATCCTATCGTTTAGCTATTTTGGGAGCTACTGGTGCAGTTGGCACAGAGTTGCTGGAATTATTAGAAAGCCGTAATTTTCCGATTGCTGACTTGAAGTTATTGGCATCAGAGCGGAGTGCTGGGCGATCGCTACGGTTTAAAGGGGAAAATATCCCAGTAGAGCCAGTGAGCGATCGTGCCTTTGAAAATGTCGATATAGTACTAGCTAGCGCGGGTGGTTCCACATCTAAGACTTGGGCAGCAGTTGCCGTGGCAAAGGGTGCAGTGGTAATTGACAACTCCAGTGCCTTTCGGATGAACCCAGAAGTTCCTCTAATAGTACCAGAAGTTAATCCACAAGCCGCAGCCAATCATCAAGGCATTATTGCTAACCCTAACTGCACAACGATTTTGATGACTGTGGCAGTATGGCCATTGCACCAAGTTAAACCAGTGCAACGTATCGTGGCTTCAACCTACCAATCTGCTAGTGGCGCAGGGGCTAGGGCAATGGCAGAAGTCAAAGCCCAAACAAGCGCTATACTACAAGGACAACCGCCAGTTGCTGAGGTATTGCCTTACCCATTGGCATTTAATTTATTTCCCCACAACTCACCATTAAATGATTTGGGTTATTGTGAGGAAGAGATGAAAATGGTCAACGAAACCCGAAAAATATTTGGCACGCAGCAAATCAGAATCACTGCGACCTGTATACGGGTTCCCGTACTCCGCGCCCATTCAGAAGCCATTAATTTAGAATTTGAGACTCCCTTTAGTGCTGAGGAAGCCAGAGAAATTTTAAATTCCTCCCCTGGAGTGAAATTGGTAGAAGATTGGGAAACTAATCATTTTCCGATGCCAATTGAAGCAACAGGTAGAGATGAAGTTTTAGTGGGAAGAATCCGTCAGGACATTTCTCATCCTTGTGGCTTGGAATTATGGTTGTGCGGCGACCAAATCCGCAAAGGCGCAGCATTAAATGCAATACAAATCGCCGAGTTACTAGTAGAAAAAAATCTACTCAAACCATTAGCTATTAGTCATTAGTCATTGGTCATTGGTAAGTGACAAAGGACAAATGACAAATGACACTTGAAAGCAATTTGCAGATAGGTTATTACAATAGGAAACCACCAAGATACAAAAACATGGGCAATCAGGAGTGAAAACAGGGTGGGAGATTTTGGTAATGTTTTAACCGCTATGATTACACCGTTTAAAGCAGACGGTAGTGTAGATTATGGTGTAGCGGCAGAACTGGCAGTGCATCTAGCTAACAACGGTACAGATACATTGGTGATGTGCGGCACAACAGGAGAATCCCCTACCTTGAGTTGGGATGAGGAATACCAGTTGTTTGTCGAAGTATTGCAGTCCGTGGCAGGAAAAGCCAAGGTGATCGCAGGTTGTGGTTCAAATTCCACCAAAGAAGCGATCGCTGCCACCCAAAAAGCGTCTAAGATAGGAGTACATGGTTCCTTACAAGTTGTTCCTTATTACAACAAACCGCCGCAAGCGGGATTGGAAGCGCACTTTCAGGCAATAGCACAAGCCTGTCCCGACTTACCATTGTTGTTATACAATGTCCCAGGTCGTACCGGACAAAACCTTCAGCCAGAAACAGTTGCCCGGTTAGCTGAGGTTAGCAATATTGTCGGGATTAAAGAATCCACTGGTAGCATAGACCAGGCAAGCGAAATTCGTCGCTTGACACCAAAAGAATTCCACATCTATTCTGGTGATGATTACATGACTTTGCCTTTGTTAGCGATCGGGGCAAAGGGTGTGGTAAGTGTGGCTTCTCATCTGGTAGGAAACCAACTACAGCAGATGATCCAAGCTTTTAGTGCGGGAAAAATTGAGGTAGCAAGCGAGATTCATCTGCAACTCTTCCCGTTGTTTAAAGCTTTATTTCTCACTTCAAATCCTATTCCAGTGAAAAAAGCGCTGAAACTCCAAGGTTGGGAGGTTGGTTCAACTCGTCCACCGCTATGTGAAGCTGATTTAGAAGTAAGTCAAAAGTTAGAAGCGGTTCTGAAAGAACTTAGTTTAATCTAGCCACCATCTAGTTAAACGTTAGTAGTCTGCTGCTTTCTAAAGATAGATATAAACAATGACCATAATTGTTCATAAGTTGCAATTTAAAAACCTGTGCTAGGACTGATAGATATACTATGAATCCTTAAGTGTACAGTCGATTTTATTGAATAAAAAATTGAAAATTTCAATTAAAACTTGATTGCTTTCAGACTGACTTAAGAGACAGATGATGTTGTCTTAAATACAAGGAAAGTTAACTATCAACTTAATTAACTACAAGTAACAATCTAAGGAGAAAATGGCTAAAAACGAAGCTAATAATTCCGCCTTGAAAATTATTCCTTTGGGCGGTTTGCACGAAATTGGGAAAAATACCTGTCTTTTTGAGTATGACGATGAAATTATCTTGTTAGATGCAGGATTGGCTTTTCCCACAGAGGCAATGCATGGAGTAAATATTGTTTTGCCAGATACGACCTATCTACGGGAAAATCGCCACAAAATTAAGGGGATGATCGTTACTCACGGTCATGAAGACCATATCGGTGGGATTGCTTTCCATCTCAAGCAGTTTGATATCCCCGTGATTTATGGCCCTAGGCTAGCAATGGCGATGCTAGAGGGTAAATTGGAAGAAGCAGGAGTCCGCGATCGCACAGAAATCAGAACAGTTTTACCACGTGATGTAGTGCGGATTGGCAAAAACTTTTTAGTGGAATATATCCGCAACACCCACTCCATCGCTGATAGTTTCACTGTTGCCATTCATACTCCCCTTGGTGTAGTCATTCACACAGGGGATTTCAAAATTGACCATACCCCAGTAGATGGTGAAAAGTTTGATTTGCAACGACTAGCAGAACATGGTGAAAAAGGCGTTCTTTGCCTGCTAAGTGATTCCACTAACGCTGAGATACCAGGATTTACACCTTCAGAACGTTCGGTTTATCCAAACCTAGAGAGAGTATTTAGTCAAGCCACTGGGCGATTATTCGTCACGACCTTTGCTTCTAGCGTGCATCGCATCAATATGATTTTGGATATCGCCAAGAAGCAGAACCGTGTAGTAACGGTTGTCGGGCGTTCTATGCTGAACTTGATTGCTCATGCCCGCAATTTAGGTTACATCAAGTGTGAAGATAATTTGCTGCAACCATTGCACGCAGTTCGTAATCTCCCTGACGAAAAAGTTTTAGTCTTAACTACAGGTTCTCAGGGTGAAACGATGGCAGCAATGACCCGCATTGCCAACAAAGAACATCCTCACATCAAAATCCGCCAAGGAGATACAGTAGTATTCTCTGCTAACCCCATTCCCGGAAATACGATCGCAGTAGTCAACACCATTGATAAATTGATGATTCAGGGTGCGAAAGTAGTCTACGGTCGGGATAAAGGGATTCACGTCTCCGGTCACGGCTGTCAGGAAGAGCAAAAGCTGATGATTGCCTTAACTCGACCCAAATTCTTTGTGCCATTTCACGGCGAACATCGGATGCTAGTGAAGCACGCAGAAACGGCTCAGAGTATGGGTATTCCCGCAGAAAATATGATCATTATTCAAAATGGTGATATTGTCGAACTGACTGAAGATGCTATTCGCGTTGCTGGTAAAGTGCCATCTGGTATCGAATTGGTGGATACTACCAGTTCGGGTATGGTAAGCGCCAAAGTTTTACAAGAACGGCAACGTATGGCTTCAGAAGGCATTATCACGATCGCAGCTGCAATTGATTGGAATGGTAAACTGTTGGCGAAACCAGAAACTCACCTGCGGGGTGTAGTTACAACTGTAGAGCGATCGCTCTTACAAACCTGGGTAAAACAACGCATTGAAGAAATCCTCACTGTGCGCTGGACAGAATTTGCTCCTGGCGGTGAAGCAGCAGATATAGACTGGGGCGGATTGCAAGGAACTTTAGAACGAGAATTGCAACGTTCCATCCGTCGAGAATTGCAATGTCAGCCATCTGTGACTTTGTTGATGCAAATCCCTGATGAGCCACCTGTAAAAGTTGCCGATGGCAGAAGACGGCGGACTCGGACTGCTGCTCAGGTAGCATCATAGAGAATTTAAGGTAAAAATCTCATACAGAGAGAAGTTTGAGCAGTGGCTTTCACCGCTCAAACTTCGATGGGCGCAAAGACACAGAATTTTTCTGAACGTCTTTGCGCTTTCTTTTCTCATGGGTATAGAGCTTGCCTATAGTTCTTCGATCTAACTTGTTAGGTTGCTGTCACTGAAGGCGTGCGTACAGCGTACTGCCAGGATGGATTGCGCTGTAGAGTACAAAAACACCCATAAGCAAGTTCACCTGATTTTAATGCGTTAGACTGTATGATTCTCAAATTGCCACTGGCAACGTAAGTTTTGTGAAATGCAATCGATTCTATTCGCTCAAAAATCCTACTTTTAAGGCATTCAGCCAGCTATGGATACGACACACTTACGTGAGAAAGTGGGAACACAGAGAGGAAAAATGCCTTCTAGGGTATTACCGATGTTTATACTTAGCAAAAATTCTTTTAGAAAGACCTTATATTAAGTTCTGTAAATGTTACACTAAAACCTATCCAATGATGGATGTCTTTATTAGAATTTAAACTGTGTCAAGTTATGAACAAGATCGTAATATTACACTACCGATCCCCAGAAATTTGCGATTAACTTGACGTAGTAATAAATTAGGTTCTGACTTAAGTGGCTAATCAGGTATTACATTATATCGCAGTCAGAACGCGATTTTTCCGGGAAAGTTCGTTGCCACGTTGTATATATTCATCAAAAAGGTGAATAACCTCAATAACACAGAGGATTAACCATGAAGGTATTCGACAATACCACGAAAAAGATTTTTCTGGCGAGCTGGGTGTCAATCAATCAAGCAGAGACTACTGACCATAAAGTAAGCCAGCTTAACCATTCTCCTTCTAAGCCTTACTGGGATATTCTCCAACCCCTACGGCAACGAGTAGAAAACATTCAAGTCCGCGATCGCCAATTAGCTCATCGTTTGTGCAAACTGATCCCATCTCAATGCCCCTTTGAGCGCGATGTCAAAGTATTTGGGAAGACCTTGTTTCACATCCCACCCATGTGCAAGCTCAACCCCTTATATGAAGAAGTGGTTGGTTTACGTTTCCGAGCGTTGTGCTATCTAGCCGACGAGTGTGGCGAAGATGTATCGCAGTACTGCTAATACTGAGATATGAACGCTGAGGAAAAAGTTAGGAGTCAGGAGTAAGAGGTCGGAGTCAGGAGTAAGAGGTCGGGGATCAATAATATAACTCCTAATTCCTAACTCCTAACCATTTTTTATTATTTTTTTACTATTTCTTTTGCCATTTTTGAATGGCATCCTGAGCATCTTCATAAGCGGCTGTTTCCTCTGGCACTAACGCAGCGGTCGCAATTGCGGCACTACGATCTCCTTCGGCAGCGCGACTCTTGGCCAGGTCTAAAATTTTCTCACTCCATTTATTGATCGACTTTTGGGCACTATCAAAGCCTGGTTGACCTGCTGGTACTTTTTTGGCAACTTCGATCGCCCGATTGTAGGTAGATGCCTGTCCAGACTTAATTAAGGCATTAGCTGCATCTAAAAGAGTTTTGTTACTCACATACTGCTTACCCTCTAGCCGCCACAGGTTAATTGCTGCTTGTGCTTTGGCGTAGGGGGCTTCATCTTTGGTAATTAATCGAGCGGCGGCAATAGCGCTAGCATATTGTCTTTGTTTAGCACGACCCTCTGCTAAATCTAAAATCATTCGGCTCCAAATCTTAATATTCTCTTGCGCTTGTTCGTACAGTGGTTCACCAGGTTTAATTTTCCGGGCTGTAGCGATCGCCATACTCAAATCACTAGCCTGAGTTTGTCTGAGCGACATTTTCGCCAAGTCTAATACTGCTTGATTCCGCTTTTTCGACTCGGAACTAGAGATGATTTGGGCGCTAGATTGATTGTTAAGTCTAACTACTGAAGTACTATCACTTGGTAAGTTCTCGATAATCTGGCGATCGCTAGCAGTAGCACTAGGCGATGCAGTTGATATTTGCTTAATTCTAAAAGTTTCTTGATTGCGAAGAAAAACTACGGCAATTAAACCTGCTACTAGCAAGCTGCCTCCGCCCCACAAGATAAACTGTTTCCAAAAAGGGAGACTTGGCTGATTTGATGGCAATCGAGAGACGTAACCTTTGGAGGAATTGGGGATAAATCTTCCCTTGGGATTCGCTCCTAAAGAAGTTTCCGCCATTGGCTGGGAAACTAAGCTAGTAGCTGACTCCTGGACTGGTTGAGCTTTAGGCTTCTCAACCTTATAAGCCTTCACCTGCTGAGAAGAGTTCACAGTAGCTTCTCCCCATCTACCCCGTTGTGCTGAAGTTCTGGGGTAATCGTCAAGGGGAGGGGCTGCAAGAGCAACAGCAAAAGATTCTTCGGGATAAATCACCGGATTTGCTTCAAAGCCATTTTCTATTGCCAATTCTGGCAAGATTATCTGCGCCCTTGATGGGATAATAGTTGCAGGGTTTTGGACAGGCCGCCAGTGGTGGTGACATAATTTTGGCATGACCAGACTTAGGTAACTTTCTAAATCTGACAGGTTACTGCCATTACCAGAACGCAAAGCTTCTAATAAAGCTGCTGTAAAGAATCCGTGACCTAATTCGCTACTTTCGTGGGAAAATTGTTCTGGTTGACAAGAAAGAATTGTCGCTAGTTGTAGTTCTTGGGCTAGTTCTATTGTTTCTTCACCAACGGGAGCATCCGCTTGAGTGCCAAAAGCGCGGTTGATATCGAGTAGTAGCAATACATTCAAGTCAGCAAGTTGGAGACTTTGCATTAGCGATCGCAATTCGATGCCAGTCTCTTGCACGAGTTCGGGGTTGCCCTCTGCTGGCATTAAGTAATCTTTGCCCTTGTAATTGACTCCATAACCGCTAAAGAATAACCACAGATAGTCTTCCGGTTGCCAACTTGTAGCTGCCAAATCCTCAAGCAGCAGCAGAATATTCTCTTTAGTTGGATAAGTTGATCGATCTCCAATTGGCGGCGAAGTATCCGTCATTAGCAGGCAATGTTTGGGGAGAAAGCCTGCCTCTGTCACCAAAAAATCCTCTAGTGCTTCAGCATCGGCTTGGGCACAACTTAAAGGTTGAAATAACTGATAGTGATTGATGCCAATCGCGATCGCCCAGTAATTTGCCATCCCGCTCTTTGTCAGTTATTGTTTGCTGGTCTTAAAATTGCGGTTGGCTTTGCCAAAAAAACAAAGCTAACCTATGTCTTATAGTCTAGGTGATTCTCATCGAATCTTAAGTTAGAATGTAATTTTTATTACGTTAGCTAGTCGGAAAATACCTTTTACCTAATTTCAATAACAGATCATCACTAAGGAGATAGAAGGTCATGAGCAAGATTGCTGCTCACCTACCATCATCGATCACTCCCTTTTCAGTTATTAGCCAAATTGCCAGAAGAATCCGGATAGTTCCTTTATTAATTTTGCTCATATCCACTGTTCCTGCGTGGTTTTTGACAGAAGCGATCGCGCCCCAGGTTGTACGAGCTTACACCGCGAGAGTCGATCTAGCTATTGACCGCCTGCCGGAAGAAAACTATGAAACCGTTCTACGGAGAGCGGAAGCGGCCGCTAGAGCAGCCGCCCAAAGGAGCTTCGACCAAGATATCTTGGTGACAGATGTTTCAATCATTGTATCCGTACAAAATTTTGGAGCGATCGCACCAGTTCTGGCATTAGATGTGAGTCGTCCCCAATGGCGATCGCGTCCCGATGCCCAAAACTGGGCTACTTACTTCAAAACTGCGCGATCGCTACTTTTCTTTGACAATAGCTCTACAGCAGCTAACGGTGTATCAAGCAAAAAATGAAGGATTGAGTTAGACACGGAGACGTAAAGAGTGGAATACTTAAAATTCCCTCTATTTCTGTGTCCTACTTCAATCTCAACTTACCTGTTGTTCTTCGCGTCAGTGGATGGCCTAGAATAAGAAGGTTGTCAAGAATCGCGATATCTGCTGACATGGCTGTTCCTAAGAAGAAAACTTCCAAATCAAAACGAGATAAACGTCGAGCTACCTGGAGGCACAAAGCCGTCGTCGAAGCTCAGAAAGCCCTCTCTCTGGGTAAGTCAATTTTGACTGGACGTTCTACATTTGTGTATCCAACGGCTGAAGAAGAGGAAGAAGAATCATAATTTCCCAGTCAGGCAAAGCATAAACAGCACCAATATTCTTACTACTGGATCAACGCTTTTTATTAGCTTTCCTGATTGCATTTTGAATCATAAAGACTCTACACAAGCTCATTAGCTCGATAAAAATTGGTAGTGAGTAATTGGGAACATCCATTACCCATTACCTATCACTGATGAGTGATAATCAAATCATATAAAAGTAAAACATCTGGTAGTGTTGGCAATTCAGCAAGAAAGCTTGTAAACACCTTGAGAAAACTTATTTTTCTCCAACTATGCTAGGAAAATTTTTTCAAAAACCAGGGAAAGAAGAGGGGGAACGGGTTCCTCCTGGTCAACACTTAGCTAAAGGTTTCCCCGTACTAACTTACGGCGCAACTCCTCAAGTCAGCATTGAGGAATGGGAGTTTCGAGTTTGGGGTTTGGCAAAACCTGCTACCTTTAGCTGGTCAGACTTTATGGCGCTACCTCAACACGAATTTACGGCAGACTTCCACTGCGTAACGCGCTGGTCTAAGCTTGATGTCAAATGGACTGGCATTAAAGTTACAGATTTCATGGATCTGATTGAGCTAGATCCAAAAGTAGCCCACATTATGGAACACTGCTACGGCGGCTACACTACAAATATTTCTGTAGAAGATTTCATCCGGGAAGAAAACTTCTTTGCCTTTAAAGTCTTTGGTGAAGACCTTCCATCTGAACACGGTGGCCCGATGCGGCTAGTTGTTCCCCACCTCTACGCTTGGAAAAGTGCTAAGTGGATTAATGGTTTAGAGTTTTTAGCTGGTGAAGAACTTGGTTTTTGGGAGCGCAATGGCTACCATCGCCGTGGTGAACCTTGGGCTGAGGAGCGTTACAGCAACGCTTTTGGATTTTAGATTTTAAATTTCTTCTTTAATCCAAAATTGGCATAATTAGGAGTTGTGGATTTTTATCCTTAACTCCTAATTTTTTTAACCCAAAAGTTTCTTTATGAGTGGTAATTTGCCCTCATAAGGAGCGTATCGCCATTTTAAATCGAGCCAGAAGGAGTTTTGCAATACACTTTTGTTATGGGAAAAAGTGTCAAAACTAGCTTTGCCGTGATAGTTGCCAATGCCGCTATCTCCTACACCACCAAATGGTAAAGACGAGACACCAACCTGCATCACTGTGTCATTGATGCAGACCCCACCAGATGAAGTTTCCTGTAAAACTCGCTTTTGCAGATTTTTGTTTTGAGAAAATAAGTATAACGCCAGAGGTTTAGGTTTAGAGTTAATCAATGCGATCGCTTCGGCAACGTCAGTATATTCAATAATTGGTAAAATTGGCCCAAAAATCTCTTCCTGCATTACAGAATCTTCCGAAGAGACATTATCAATCACTGTGGGAGCGATATAACGCTCTGAAGATTGATTTTCTCCACCGATGATAACTTCACCGTCTTTGAGAAAACTAACCAATCTATCAAAGTGTTTTTGACTGATAATCCTGGCATAATCAGGACTACTGACAGGATTATCACCATAAAACTCTTTTAGGCATTTTTTCAGCCCATCTATTAAATCTTTTTTGATTTTTTTATTAACTAAAAGATAGTCAGGGGCGATACAAGTTTGTCCAGCATTAATAAATTTGCCCCAAGTGATTCGTCTGACAGTGTGTTCAAGATTAATATCAGTATCTACTATACAAGGACTTTTACCACCCAATTCTAAAGTCACTGGTGTGAGATATTTGGCTGCTGCTGCCATAATAATTTTGCCGATAGCTGTGCCACCAGTAAAAAAGATATGATCGAACTTTTCTGCAAGTAGTTTTTGACTTGCTTCCACATCTCCTTCTACGACTGCAATATAAGCTGGGTCAAAATGTTTGGTAATAATCTTAGCAATGACATCAGAGGTATAAGAAGCAATTTCTGAAGGCTTGATAATTGCACAATTCCCGGCTGCGATCGCACCTACTAACGGTGAGATAATTAACTGAAATGGATAGTTCCAAGGGCCAATGATTAAAACAACCCCTAAAGGTTCTGGATAAATTTTTGCTGAGTAGGAAAAAAAATCAAAGGAAACTGGTGCTTTTTTGGGCTTAGTCCAGGTATTGATATGTTTTATAGCATAATCAATTTCCTTAATTACACCTATTTCTGTAATGTAAATCTCCAATTCTGGTTTATGTAAATCTGCTTTTAATGCCTCGACTATTGCTTGTTCATGCTCAATTATGGCTTGCTTGAGATTTTTAAGTTGTTCAATGCGAAAAGTAACATCTTTAGTTTTACCAGTTTCAAAAAACTCTCGCTGATTCTGGATAATATCGCCAATCTTAGATAATTCAGTGGTAATCATTGTTGGGTATCCTCAAAAACTATGTTTTTAATGTGGCGTTGCTATCTCAGCATATTTAATTTGTCATTTTTTAGCGTTTGACTTTCTAATTAAAATATTTACTTGGAATTATGGGGAGATATTAGTAAAGTTATAATTTATGAAATATCAGGATAAAATATCCCGTAATTCATAAATTATAATTGCTAATTTTCTCATGTTGTGGCGGGTAAAAGGACAATAAATACACTACCTTTCCCCAATTCAGAATTCAGCAAAATAATACCTTGATGTGCCTCGACAATTCGACGAGCAAGGTAGAGTCCTAAGCCACTACCAGAACTCTTGTGACTACCTTGACGAAATCGTTCAAATATGGTGGACTGTTCTTCGGTGGGAATCCCTGGGCCAGTATCCGCGATCGCAATGCTAATATATTCAACGGGATTGGATTTTCCAGATAACTGAGATTGGCTACTTTTGTCTAACTGTCGTTGAGAAGTAAAACGAATAGTCACAGACCCGGAGTCGGTAAATTTGATTGCATTGCCGATCAGGTTTGTAAATAGACGATGCAATTCTAAGCGATCGCCCATAACTGTATTTGACTCTTCAGTAAAATCCAAATTTAGCGACAGTGTTTTAGCTTGAGCTAGTGGTGCTAATTCTCCAGTCACCTCTTCTAGCAAACGTCCCAAATTAACTGGTTGAAATGCCAAACTTTTGCGACCTGCTTCAAAGCGATAAACTTCCAATAAGGTATTGACCATAGTAAGCAGGTTGATATTACTACGGGCCATAATGGTGATTACTTCCTGCATTTGTGGTGATAATGTTCCCAATGCACCTTGCTGAAATAGCATCAACATGCGATCGGCCGCCACTAAGGGAGTGCGTAAATCGTGGGTGAGACGAGAGACAAAATCTTCTCGCTGGCGGGCAATTTCATCACGTTCATCCATACTATGCTTCAAACGTAGGAGCGATCGCACTCGTGCCAGCAATTCATCTACAGTTACAGGTTTACGGATAAAATCATCAGCACCCAAGTCTAATCCGTGAGCAACGTTGGGTGCATCGTGGGCAGTAATCAGCAGTATGGGGATATATTGCGGCAGTTTCATATCACCGCGAATGTGCTTGGTGACTTCGTACCCATCCATATCTGGCATCATCAGATCCAGCAGAACCAAGTCACAAGGAGAAGCTTTCAATTCTGCTAAAGCCGAAATCCCATTTTCTGCGGTGCTAATCGTGTAACCTTCTTCCTCCAAGATAGTTTTGATCAAAAACACGTTATCAGGAGAGTCATCAACTACCAGAATTTTGCCAGAACGAGAAGATTGTGAAGTCATATAGATGCAGGGTACGGGATAAAAGCAAATTTTTAGGGAAACTGGTTTATTGGTATAGTTTTTTAGATAGTTCTCTTAAGTAAACTTCCTCCAAAGAAAATTGCTTACTAATAAATTTATATAAATGTGTTTTAAAAACTACTTTACTTACCTTTTTAGCAGATAGCTACAAACTAATTGAATTATGGCTCGTAATTTCTAGTAATAGAGTTCCCTAAAACTCTGAAAAAGTAACATATAATACTTAGGATACCTCCCTGCAATAATATTTTTTTATACATAAATAAATTAGGGTTACAACAATTGTTGTAACCCTACAAAACGCTATATTCAATCTGCTCAAAAACCACTATAGAATAACAATTAACTTCATAACTACCGAATTATGAGCAATTCTTTACATTGACTATATGTAGATTAATAGTTTGCAAAGGTAAATACTTTCTTGCTTGCCTGCGTGGGATAAGTGACGCTAGTGTTAAAAGAAATCGTGCAAACTAAAACCCTCATCCCAGAAGTCGAGTAGGAAGCTAGAATGGCAATTCCAAATAAAGAAGTAAAATCTAATACAGATATTTTAGATAATAGACGCACCCAAACTCGCATCCAGGTTCGTATTCCTAAAGACTTGCATGAGGAACCAGTCATTTCACGACTGGTTTCTCACTATGGGATCACAGTTATTATTGCTGATGCTCAGGTAAGCGCAAACGTGCCACAATATAGCTGCTTCGATCTGGAACTGCGAGGTACTGTTTCTCAGATTGAAAGTGCCCTAACTTACCTGGATGAACTGGATTTAGAAGTTTTGCACCAATCCAGCCCTGAAGAAGATGGTTGGTAAATTGAGTTCTCAGTCCTGAGTTATGAGTGCTGAGTCAAAAACACTCAGCACTCAGCACTCAGCACTCGTTACTGATTTTAGGCCATTTGATTTTCAATCGCCCACCGCGCTAGTTCAGTGCGGTTATGGAGATTGGTTTTGCCCAACATATTGGACACATGGCTTTCAACTGTGCGCTGACTAACATTTAGTTCTTCAGCAATTTCCCGGTTAGCTAAACCCCTAGCGACAAACTGGACTACTTTCAGTTCTGTTGGGGTTAATTGCACATCGAAGGGAACCTGGATGCGGGAACCATTTTCGCCTCCTTTTGCTTGGTGTTCTTTCCAACGGATAGTTTGTTTCAGCGAGGATTCAACTTGGGCTACGAGTTCTTCTGGTTCAAAGGGCTTGACCATATAAACATCAGCACCTTTATTCAGACCCTTAACTCGGTCTGCGCTTTGTCCCTTAGCTGAAAGGAAAAGAACCGGAATCCAACTGGTGCGTTCGTTTTGCCGGACTTGTTCCACAAAAGTATATCCGTCCATTTCCGGCATCATCACATCGCAGATAATCATGTCTGGAACATCTTGCTCTAAAATTTCCAGAGCTTCACGTCCATTTTCGGCGGTGATGACTTCGTATCCCCGGAATTCTAAGTAATCCTTCACCAGCAAGATGAGGTTAGGGTCATCATCAATCAATAGAAGTCGTTTGTGATCTTTCATGCTGGGCTCTTTCATAGCAGTGGCACTTGTCGCGCTTCGGTCCATCAAAGTCTTGAATATTTATCCTCTATGGTGGGTTATTTTGAGATGTTGTCCTTTTTCCTACTTAACTTGCCTTTGCTGTCTCGAAGTCTCAAAAATGCCGAGCATTTTCAAGAGACTAATAGCTCGATAGCAAAAGTCCAGCAAGGATACGTATAGCAGTAGTATCTATAATGCGCTATTATATATCGCATTGAAAGTGGCGGGCGAAAAAACACTGATTAAATAATAATCCTTCTGACTCACAAGTAAGTATTGGCTTAAAGATGACCCTACCTCAAAACCAACCCGCACTTTCTTAAAGCTTACTGCTGTTCCATATCCTTCGGTTGTTAAGCCTCTATGAGGTGTTCACAAGAAACTAGGGAAGTTTCTGGCAAAGGATGGTTGAAAAACGCATATTCTTTTACCACCTTATTGCCTATTAAGTGTTCTTGGATGATCCGCTCAATAACTTCCAGGTTTGCTTGGCGATACCAGACACCATCAAGGTAAACCACCATTATGGGTCTAGAACAACAAACGCGCAAGCAGTTGGCTTTAGTTCTGTAGACGCATAAGGAATAATTCTGTTGCGACTCATCAAGTTTTAACTCTTTAAGTCGCTCTTTTAAGTATTCCCAGAATTCCAGACTAGCTCGTTTTGAGCAGCAATTAGCAATTGTCTGGTCAGCGCAAATAAAAATGTGTCGCTGAATTTTTGCAAGTCCAAAACTTTCTACACAATTACTCAGGGCATTATATTCTACTAGAGATTTAGTGGCTTTGGGGATTTGATGGCTTGACTGGATCACTGTATTGTTACTTATCGAGCAGCTCCCTGATTACAGTTCTATAACAATTTCCCAGCTTTGCAAATAAAGTTGACTGAGAAGAGAATGGGGCATTGGGCAACTTGTACTGAGCAGAGTCTCTCAAATATAAGTATTGGGCATTGGGAAAACTCTTCACTACTCCCGACTCCCTATGACCATATAAAAATATACGTAACTTACAGAGCAGAACCCGAAGGATATAAATAATTAGGCATTAATACTTAAGTACATCAACGCTCTTCTAGTTCGGGAACCCGTACTCAAGCAATTCTTGCCATTGGATGCCAATTTTAGGTAAATTAGCACTCAGGGGTTGAGAGTGCTAATCTCTGGAGAAAATAATTATGGCAGCCTTATCTTTAAGCGTTTCTACAGTTAAACCTTTGAGCGATCGCGTTTTCGTAAAAGTGAACGCCTCAGAGGAAAAGACCGCAGGTGGTCTGTATTTGCCCGATACCGCCAAGGAAAAGCCCCAGGTAGGGGAAGTAGTTGCCCTTGGCCCTGGCAAGCGTAACGAAGACGGTAGCCGTCAGGAATTGGAAATTAAAGTCGGCGATAAAGTGTTGTACTCCAAGTACGCTGGCACTGACATCAAGCTCGGCACCGAAGAATATGTACTGCTTTCTGAAAAAGATATTTTAGCAGTCGTTATTTAGTGGTCATTAGTCATTAGTCATTAGTCATTAGCCAATGACAAAAGACAAATGACAAATGACGAAGAACAAAAGACAAATGACAAAGGACAACTAAAACAATTATGGCAAAGCGCATTATCTACAACGAAAACGCCCGTCGCGCCTTAGAACGAGGCATTGACATCCTGGCTGAGGCTGTAGCTGTTACCCTTGGCCCCAAAGGTCGTAACGTAGTCCTAGAAAAGAAATTTGGCGCACCGCAAATTGTTAATGACGGTGTAACGATCGCTAAAGAAATCGAATTAGAAGACCACATTGAAAACACTGGCGTAGCTTTGATTCGTCAAGCTGCCTCTAAGACCAACGATGCTGCGGGCGATGGTACCACAACTGCTACCGTTTTAGCTCATGCGATCGTCAAAGAAGGCTTGCGGAACGTTGCAGCTGGTGCTAACGCAATTTCCCTGAAGCGTGGTATTGATAAAGCTACTGCCTTTTTGGTAGACAAAATCAAAGAACACGCCCGTCCAGTGGAAGATTCCAAAGCCATTGCCCAAGTTGGTGCAATCTCGGCTGGTAATGACGAAGAAGTCGGTCAGATGATTGCCCAAGCAATGGACAAGGTGGGTAAGGAAGGCGTAATTTCCCTAGAAGAAGGGAAATCTATGTTCACCGAGTTGGAAATCACTGAAGGGATGCGCTTTGACAAAGGCTACATCTCTCCTTATTTCGCTACTGACCCTGAGCGGATGGAAGCAGTTTTTGATGAGCCTTTCATACTGCTGACCGATAAGAAAATCGCTTTGGTACAAGACCTTGTACCAGTGTTAGAGCAAGTAGCTCGTGCTGGTCGTCCTTTGGTAATTATCGCCGAAGATATTGAAAAAGAAGCTTTGGCAACCTTAGTAGTAAACCGTTTGCGCGGTGTACTCAACGTGGCTGCTGTTAAGGCTCCTGGTTTTGGCGATCGCCGCAAAGCACTACTAGAAGACATCGCTGTTTTAACTGGTGGTCAACTAATTACCGAAGATGCTGGTTTGAAGCTAGATAACACCAAGCTGGATAGCCTGGGTAAAGCTCGCCGGATCACCATTACCAAGGACAGCACCACAATTGTTGCCGAAGGTAACGAAGCTGCTGTTAAGGCTCGTGTAGAACAGATTCGTCGTCAAATCGATGAAACCGAATCTTCTTACGACAAAGAGAAATTACAAGAGCGTCTTGCTAAACTCTCTGGTGGTGTCGCTGTCGTGAAAGTTGGTGCAGCGACTGAAACCGAAATGAAAGACAAGAAACTGCGCCTAGAAGACGCTATCAACGCCACCAAAGCTGCTGTGGAAGAAGGTATCGTTCCTGGCGGTGGTACAACTCTGGCTCACCTTGCTCCTGAATTGGAAGTTTGGGCGAAGAGCAATCTTAAAGATGAAGAGTTGATTGGTGCTTTGATTGTTGTTCGTGCTTTACCTGCACCTCTGAAGCGGATTGCTGAAAACGCTGGTCAGAATGGTGCTGTGATCGCTGAACGCGTTAAAGAGAAAGAATTCAATGTTGGCTACAATGCTGCAACAAACGAATTCGTCGATTTGTTAGCTGCTGGTATTGTTGACCCTGCTAAAGTGACTCGTTCTGCTCTGCAAAACGCTGCATCCATCGCTGGTATGGTGTTGACAACCGAATGTATTATAGTTGACAAGCCTGAACCAAAAGATGGCGCTCCTGCTGGCGCTGGTGCTGGTGGCGGCGACTTCGATTACTAATACTTTGTAGTTACATAATTTGAAAAACAGCTGCTTCCTGATGGATGCGGCTGTTTTTTTGTGTCAAAAGAAGAGGAAGAGGGTGAGTTACGACAACGCTTGTAAATATTTAGCTGAACAGTACCCTGCTGATTTTGTCCGTTGGTTTCTTGGGGTAGAGGTGCAATAAATTGAAGTATTAAAAACGGAACTTACGCTTGAACCAATTCGTGCAGATTCTGTGACATTTTTGCAAGCAGCTAACCAAATTTTGCACATTGAATTTCAAACTTTGGCGAAATCTAATCCGGCGCTTAATTTCCGAATGCTCGATTATTCTGTGAGGTTGAAGCGCCAATACCGTTGTCCTGTAGTGCAAGTGCTAATCTTTTTGCAGGAAACTACTAATGAAATGGCTTTTACTGAAGAATATCGGGACAACATGACGATTCACCAATATCAGATTGTTCGTCTTTGGGAGCAAGATTCAACACTATTTTTAGTTAATCCGGCGCTGTTACCTTTAGCAAGTTTAACGCGAACTGACTCGCCGCAAAGTTTGCTGGCACAAGTGGCTGAACAAGTCGCTACAATTCCAGATAGAGAGGAGCAACAAAATATTGCGGGTTGTGTAGAAATTCTGGCAGGTTTGCGGTTTGACAAGGATTTTGTTCGGCAATTTTTACGGGAGGATATTATGAGAGAGTCTGTAATTTATCAAGATATTGTTCAAAAGGAAGCGTTTAAATTGATTAGTCGTCAGCTTCAAAAGCGTTTTGGTGATAATATTGGTGGCTCATTAGTTGAGCAGGTTAGGAATTTATCTGCTGAACAGTTAGAGGATTTGGGAGAGGCATTGTTGGATTTTTCTGAAGTTGATAATTTAGTAGCTTGGTTAGGGACTTCCAGAAAATAAAATATACAGATAATAAAAATGATAATCATTGTTAGGGGGGTGGGAGAGGCTGCCGTTGGCAGCCTCTCCCACCCCAAGTTGTAGTAAATTGAATGATGATTCGATTTTGGGATGTTTGAGGTGTCAATACAATTAACAGATTCATTGAAAAAGTTATTGAAGGAAACCGCACATCAATTAAAGGGAGCAGCTAAACGTAGGTTCATTGCACAAACAGTTGTGGCATTAGGACACGGAGGAAAGTCTATAGCAGAGCGAGAGTTAGGATGGAACCGTGTAACTATTGGTAAAGGAATTAAAGAATTAAATAGTGGTATCACTTGTGTGGATAATTATCAAGGTAGAGGAAGAAAAAAAGCAGAAGAACACCTACCAACTCTTTTAGAAGATATCAAAAAACTAGTCGATTCTCAAAGTCAAATAGACCCGACTTTTAAAAGTCAAAGACTCTATACCCGACTGGGCGCATCTGTTGTAAGACATCAATTAATTGAAAAATTTGGTTATGCTGAAGAAGAATTACCAACTTCAGAAACAATTCGTGTCAAGTTAAATGATTTAGGGTATCGCCTCAAGAGGGTTGCCAAAATTCAACCTCAAAAAAAATTCCCGAAACTGATGCAATCTTTGAGCAATTAGCTATAGTTCACCAAGAAGCTTCAGATGACCCAACTATTTTACGTTTAAGCTTGGATGCGAAAGCTCGCGTAAATATCGGCTCCTTTGATCGTGGTGGTAGAAATCGAGTACCAACAGAAACTGATGACCACGACTTCAAACCAAAAACAACTGTAGCTCCTTATGGTATCTTTCTTCCAGACCTTGACGAGCTATTTTTGTATTTTACAGAATCCAAAGTAACTAGCGATTTTATCGTTGACATTTTAGGGGATTTTTGGAAATCAGAAAGCTGGCGATTTTCGGAAATAAAAACTTTACTTATTAATCAAGATAATGGAGGAGAAAATAGTTCTCGACGTACTCAGTTTATGAAACGTATAGTTGAATTTGCTCAATCATACAAATTAAATATACGTTTAGCTTATTACCCTCCCTATCACAGTAAATATAATCCAATTGAAAGAACTTGGGCTGTTTTGGAGAATCATTGGAATGGCAGTATTTTAGACGATGTGGAAACTGCATTAAATTTTGCTAAGACTATGACGTGGAATGGTAAAAGTCCAGTTGTTAAGTTAGTTACTCAGACTTACTCTAGCGGAGTCCGTCTAACTAAAAAAGCTATGCAAGAAATTGAAAATAAGATTGAACGTTTGACTAATTTTACCGAAGATAATTTACCAAATTTAGGTAAGTGGTTTATTGATATCTGTTGTGGAGTAACGTAATTTTCAAAAAGTTAAAAGCGCAAAAATAGTCGATAGCAATTCAGCTCACTGCATTTAAGAACTCTCTTTGTGCAGACATTTATCTTGCCTATTTATTGAGGGAGAAAGGGGTTGCCGTTGGCAACCCCTTTCTCCCCCTTAAAATGATTATCATTTTTATTGACTGTATATTTTATTCTCTGGAAGTCCCTTAGAGAAGCAGGAGAGAGACTAAAATTTTTACAGAAGGATATTATTAAATAGTCTGCAATTTATCAAGATATTTTGCAGCAATAAAACTAGGTTAATAAAATATAACCTGATGTCTACTAAATCAGCATTTTGAAGAAATTGACGCATCGATTTGGCAATCGGAATCAGTAAGTTGCTTGGTCACGAACTAAAACAAAAAGTACCTCTGTGCCATTGGCAAAACTGTCGCAGGTTCACAAATCAGCAACTCACCATCTGCCCTAACTTGATATGTTTCTGGATCTACTTCAATGTGTGGTAGTGCATCATTCAGCTTCATATCACGCTTGCTCAATTGGCGTGTTCCAGAAACTGCTACTGCTGCCTTTTGTAAACCTAGCTGGCTAGGAATTTCGTTCTCTAAAGCTGCTTGTGAAACAAAAGTTAATGATGTGGCATGACGCGCCCCGGCAAAACTACCAAACATTGGGCGCATATAAACTGGTTGCGGTGTGGGAATACTGGCATTAGCATCGCCCATTTGCGACCATGCAATCATTCCGCCTTTAATCACTATCTCTGGTTTCACGCCAAAAAACGCGGGATGCCACAAACATAAATCTGCTAATTTTCCCTCTTCCACTGAACCTACATATTGAGCAATTCCATGAGCGATCGCAGGGTTGATTGTATACTTAGAAACATATCTTTTTGCCCGAAAATTATCTGCTTTTTGCTCATCTCCCTGTGGGTTAAGAATTCCCCTCTGCACCTTCATTTTGTGAGATGTCTGCCAGGTGCGAATTATCACTTCGCCTACCCTTCCCATTGCCTGAGAGTCGGAGGAAATCATACTAAATGCGCCTAAGTCGTGCAAAATATCTTCGGCGGCAATGGTTTCTCGGCGGATGCGAGACTCAGCAAAAGCAACATCTTCAGCGATCGCAGGATCAAGATGATGACATACCATCAACATATCCAGATGTTCGTCTAAGGTGTTGAGGGTGTAAGGACGTGTGGGATTAGTGGAAGATGGCAGAACGTTGGCTTGACCGCAAACTTTGATGATATCTGGCGCGTGTCCGCCACCTGCGCCTTCAGTGTGGTAAGTGTGGATGACACGATTCTTAAAAGCTGCGATCGTATCTTCGACAAATCCGGCTTCATTCAGAGTATCAGTATGAATCGCTACTTGCACATCATATTCATCGGCAATACTGAGGCAGGTATCAATTGCTGCGGGTGTGGTTCCCCAGTCTTCATGAAGCTTTAACCCCATTGCACCGGCATTTACTTGTTCTACAAGTCCTTGGGGTTGACTGGCGTTACCTTTACCCAAAAATCCTAAGTTGACGGGAAAAGCATCAGCAGCTTGCAACATTCGGTAAATATTCCAAGGGCCGGGAGTGCAGGTAGTGGCGTTTGTACCTGTGGCGGGGCCAGTACCACCACCGATCATAGTGGTAATACCGGAAGCGATCGCAACTTCAATCTGTTGGGGGCAAATAAAATGAATATGGGCATCAATACCGCCAGCAGTGAGAATCATTCCTTCACCGGCTAAGGCTTCAGTTCCGGGGCCAATAATAATATCTACATTGTCTTGAATATAAGGATTTCCGGCTTTACCAATTTTGAAAATCTTGCCATCTTTAATGCCGATATCTGCTTTGACAATACCCCACCAATCGAGAATTAAGGCATTGGTAATTACTAAATCTACAGCACCATCGGCGTTAGAAATGGGGGATTGTCCCATTCCATCTCTGATGACTTTACCGCCGCCGAATTTAACTTCGTCGCCGTAGGTGGTGAAATCTTGTTCAACTTCAATAAATAATTCTGTATCTGCAAGTCGGATGCGATCGCCTACTGTTGGGCCGTAGGTTTCGGCGTAAGCGCGGCGATCCATTCTGTAACTCATAAGTGTTCCTCACAAACTGCGAATTTGGAATTTTTCAAACCTCATCTGGAAACCATTCCCTTCTGGTGAGGCACACATCACACCTACACTTACTGTTTCCGTTTGAGTCAAATAAGCGAGCCGCAGCATTGTATATTCAGTTCCATTCAAAGAGTATTCCACTTCTATTGCTGTGTCGCGTCGAGTTACACGCAGCCAAATTAAAGATGGATTTTGTGGCATTGGAATAACAGACCAATCTGAGTAATTGCGTGTCACAACTGCGCTAATTTGTTGCACGCCATCGACAAATTCAATACCACATTTCAACCAATTCAACTCATCTAAACGTATCATCAACCCAGCTTGATCGTATAAATCCTGATATTGTCCGCTGATTTTCACTTCAGCAATAAAGTCACCTTGAATTTTTTGATAAAAAAAGTGACCATTATCTCTAATGAAACCGTAGTGAGTTTCCCGCCAGAAATCTGTTTTTGCGCCGGAAGCGATAGTGATCGCTTCGTCTTTTACTTCCCAAACAGGCGGTTCATTGTACCATTCCATGTTCATAGCTACAGAGAACCGTTAATTTTGGCGTTGAAACCGTAGACTTGGCGAGTACCAACTAAGGAGACTAGAATTATTTCTTTTTCATCGCCTGGTTCAAAGCGGACTGCGGTTCCGGCGGGGATATCAAGGCGCATTCCTCGCGCTTGTTCTCTGTCAAAGTTTAAGGCGGCGTTAACTTCATAAAAGTGATAATGGGAACCTACTTGTATGGGGCGATCGCCTGTATTTGACACTTGTAATTTTATAGTTGGACGACCAACATTTAGTTCAATTTCACCTGCTGGTGTGATAATTTCCCCAGGAATCATATAAATTAAAATTTCTAAACTTTAACGAATTGGATTATGTACTGTCACTAACTTTGTGCCATCAGGAAAAGTAGCTTCAACTTGCACATCATGTACCATTTCTGATATCCCTTCCATGACATCATCCCGCGTTAATAGTGTTGTACCATAACTCATCAATTCAGCCACAGTTTGCCCATCTCTCGCTCCTTCTAAAATGGCAGCAGAAATATAAGCGATCGCTTCAGGATAATTCAGTTTTAAACCCCTTCCTTTCCGTCTTTCTGCTAATAAAGCAGCAGTAAAAATTAATAGCTTATCTTTTTCCTGCGGCGTAAGTTGCATTCTTATCTCCTCTGTGTTCTCTGCGCCTCTGCGGTTAGTTTAAACTTGCCACACTCTTGGTATGCAATTACCACGATTCAAAAAAGAAACTCGCAGCATCTGCCAAACATCAATAAACCAGTTTCTCACCTCAGAAGTAGAATAACCGCGATATCGGCACAATAATCCATGTTGTAATCGGCTAACACCCGCTTCTCCTTCCCCATTCCATAAACTTCGTGTTTTTTCGACAATTTCTCCTGAAACTTCACCACCAACCCAAACTAGACTACCTACTATTGGTTTTCCAGCCAAGCCGTGGGGACTGTGGAAAATGTCTTCGCTACCCCGTAACCATTGCCGATCAATCCATAAAGGAACGCCTTGCTGCCAAATTTCTGTGTGCGATCGCCATTCTCCAAGGTAAAATTTTTCTCCTCTAGCACTGCGACCAAACCGGGTAATTTCCCAGCCTAACCAACTGGCCCCGGTTGCTAATTCTACCCGTAAATCTTGCCGATAAATCGCGTCGTTAAATAAAATTGTCTCCTGTGGCAACCATTCTAAACAAGCACCAGCGTCAACTTGCATTTGGATGGTTTGTCTAGCTTGTAGCCCATTACTGCGATATATCTTGCTTGCAGCAGCTGTAGTAATTAAGGCTTGGGCTTGTGGTTGGAGGTGGATGTTAGAGGATAAGCGATCACCTCCCACCATTCCCCCAGCTGTATGTAAAATTACGCTATGACAAACTTTTTCCCCTTCTGGATAAAATGGGCGTTGTACCTTCAGGGGCGCTTGTTGGTGATTGTAAATTAACTGGGTTGCATCCTGGCGATCGGCATAGACTAAATTAAGTTTCCCATGCCAACCTTCTGCTATTTGTGAGTTACAGGTCATTTATAAAGTAAACATTAAGTTTCAGGTGGATTACATTTCATTAATTCACTCTGCCAGTGTTTTACCTGCAATTTATCATTATTTTTTCACGAACTGGAATAACGGATGATAATCTCAGACAAAGACACCAAGAAAAACTTTTGATATCTGGAAGAAAAGGGGTGCGTAGGCGTAGCCCGTCGTAGGCATCGCTGTAGTTCAGAAAAGCGAATAGTACTCCTATTTGATTTATGAACTGGTTTTTAAGGTAGTTAATAAATCAATACAGTTCAGTTAAAGCTATAAATCTTTGCCAAAGTCATTTTTTCTAACTTAGATGCAAAGCGTCTACTCTACGAGTTCTCCAACGGAGTATCGACGCGCATTCGAGAACGTAGAGCAGGACGCGAAGAGAAGAAAAAAATGCATAACCCAAGGGTATTAGCTAATAGACTCATCCGCGAATCATGAAAGCTTACCAGGAGAGAGTTACAAGGATTTGCACGGAAGGAGCGATCGCCATCTGGCTGTACGAGGAAATAAGGGTTTGAAGGCATTGAGAGAGAAAAAAATGGAATTAGAGCAAAAACGTAGAATCAGAATAAATGAATTTACAAATAGCAAATTAAGTACTAAGAGTAACAGAAAATAACCGATTAATTCTTAATCTTACCAGCCCACAAACAGCCAGAATTACCTGATTATATCGATGTCGAGCTAGACGGAATCTATCACTGGCTACTCGAAATATTTTTACCCGACATATCATGTGTTCAACAGCGATTCGGCGTGACGAAAGTTCTTTATTCTCTTGTTTTTGTAATTCCGAGATTTCTGTATTTTTTCGTTTCTTATGAGGGGTGGTAATGGCATCATCTCCTATATAAGCTTTATCGCCGAGAAACTGTTGCGTGTCAGTAAATTTATGGCGGGTTTCTCGAAATAAATTAATATCGCTTGTTTTCCCTAACATTCCGACACGGACATCGACAATATCTTCCCCTCCAGGTAGAACAATAAATTGATTTTTCAGAGTGTGCATTTTTTTCTTGCCAGAGTAGTATCGTTTTTGCTCTTGATAGTCTACAGGTCTTGCTGTAGGTTGTTCAGTGCTATCGACAATTAATTCGTATTCAGACAGCATTCGCTGTAATTCTTGATATTTTTGACTATCTGTTGATACTTCTTCTATTTGAGATGCTGGTAAAATATCTCGCAAAATATCTACCCAATAATTGAAGGCATCATTGGCTTTAGTTTTGGAAATGTTAAACAGCAACCCTAAAATCTCAAAAATTGGTTTTTGTCTCAGGTAAACTAGACATAAGCATATTCCTTCTTTGGCTGACATTTCTGGTTTACGCCCGCCTCCAGGAGCGATAATCCGAATTTTCTTTTTTTCAATTTCTGCCTGTTTTTCTATATGCCTTTGCTCTGCCAGGCCGACCAATGCTAAAAAATGGTCATAACTAATTCCAATTAGGCGTTTAGCTTCATGAGGATACGATTCAATTCTTGCCAAAGGACTTGTCATATTCTTTCCACATAATTGCTACTCCAACTTTTTATTATCTCATGCTATTTATATTAAGGATAAGTCTAATAGGTAACTGAATTACCAATTACGAATTATTTAAGAAACACCAGTCCACTATATAAATGAAAAGCTGAATCCCAATTAGTCTGTTCCCTGCGAAACAAATGAATATGTGACTTGATATGACCTAACATTTCTGTTTGGTCTAATGTTGTATCTGCAAATGATGTGAAATCTGACCAAATTTTAACTTGAGGTAGTTGCTGATCAATCCAACTTGATAAACTATTCCAATTAATTCTGATTGTATTTTGGCTAGCTTGGGGAATGATTTTTAAACCTTGCTGGAATTCATAGCCGTTATCATAGAATCGGAGAATGCAACGTCTACCAGGTAAGTGTAAATCACAAAACTGAGCATAGTCTTGTGTTTGAGTTTTCCATTCCAGTTTACGGCGGGCATCAACATCTACAACTTGTTCAAAAATGGGCAATAGTCCCACTACTCTGGCTGTGACTTCTGACCAGTCAAAGGTGAGAGAACCGAGTTGATTTGTGTCATTACAGCAAACAACAGTAGCTTGTGGGGTAGATTCTTGAAAATGTTTGACTTGATAAACTTGAATTTGCTGAATTTGAGCTAGTGATGCCCAAAAGCAAGGAATACCAGCCTGCTGTAACTGTTTGCCGTAAAATTTTAGTTCTCCCACTTGTCCAGTACGGTACAACCTCCAGCCACGACTTGGCATTAATAGCCGTGCGGTATAGGGATCTAGTTGCATTATCTGGGCAAATTTTCGAGATGCGTCCGTTTTCATCTCGTTACTGAGTGGCTCTAAAACTAGTACGCCAAGTTCAGTGTTATTAGGTTCAGATTTTGCTTGGGAAATGGCTCTTTGTCTTTGTTCAATCTCGATTTCTTGCAGTCGTTGCAAACCTTGACGTGCTAGCGACACTATTTTGGTATTTGTCGTATCTTGCAGCAGTTGCCGATAAACTTTTTCCGCATCCTGATACTTTGTGGATACTTCATGCAACCGACCAAGATAAAATTGCACCCAAGGATTGTCTGGTGATTCTATTAGCAGCTGTTTGAGTAATTTGGCAGCTGTTTGATAGTCTTTATGGTCAAAGGCGATCGCAACTTGCTCAATCATCACTTACTTTAAATACAGGATGGAGTGATGTCTCGCGCAAAATCACTTTTGCGTGAGCTATAAATCATTTATACTTCACAACTTGCGGTAATTAAGGATAATGCTACTACTGGGGCTGTAACTGCTCTCAGAATGCGGCGACCAAGGGAAACAGGTTGAAATCCAGATGCGATCGCATTCTCAATTTCTTGTGTTGTCCATCCTCCCTCTGGGCCAGTAGCAATGACAATTGTTTCTTGTCCTTTGTCATTTGTCATTTGTCCTTTGTGCTGTAAGCAATGTTTTAAATGGGGAAACTCACCACGCGCTTCACAGATATATTGCTGACTGTTGGCAAATGACAAATGACCAATGACTAATGACAAACCCGTATTAAAAGCAACAGGCTCTAAAATTGTTGGCACAAAAGAGCGCTCTGATTGTTCGGCGGCTTCGGCTGCGATGCGCCGCCAGCGTTCGAGCTTTTGAGGACTAGGATCAAGCAAAGTGCGATCGCTCAATACTGGTGCAATACAAGTTACTCCCAACTCTGTACAACACCGCACCACTTCATCAAATCCATTGCCTTTGGGTAACGCCACCATCAAGGTAATTGATACAGGTAATTCAGTTTCCACCAAAAGCGCTTCTAAAACCTGTGCTTGCTCCCCTGCTAGCTGCGCTAACCACCATTTCCCTTTACCATCCATTGCAATAAAGCGATCGCCTTCACGCAAGCGCAATACACGCCCCAAATAATGTTGTTGTTCTTTGGTGAGTAAAATTTGCCCTTGTTGAAATTGGGAGGGTGCGATCGCAATTCTTTGCAGTTGAGACATTTTTCTTAATGAATTATTGCCCTGCTGTAGATATCTGTTGTCTAACCCAGGTACGGAAAGCACGAGTTGCTGCTATTTGTCCAACTTTCTTGCTTTCTTGGATAAATCGGGGAATCTCTGTTAATCGCACAGGTGCAAAAGTTGGACTGCGATCGCTTTGCGAGTATTGTCCATTTTTAAGGGTGTAGATCCTCAAGACATTTCCGTTATACCGCCAGAATTCTGGGACTTCCATTGAAGCATAAAGGCTTAACTTGTCTATCTTGGATCTGGAATATTCTACTTCCAGTACTATGTCTGGTGGTGGGTCTGTATTCAGGTCAATATTTTCTTTGTTGCGGACTAACAATTCATTTTGGATGTAGTAACTACTGTCCGGCTCGCCTCCTTGCTCCAAATCATCCCGCGTCATAGTCAACGAGCCAGCGCTTTTAACTTCTAAACCAAATTCTTCACACAGCACAAGAACAAAACCTTCAATGAGACGGTTTGAATTCTCGTGCGGCATTAGCGGAGTCATGATTTCTACTATTCCGTTGTCATAAGCTAGCCTTTTATTTCGCTCAGATCCCATATCTGCCAGCATAGCTTTAAATGTCTGCCAGCTTATGTTTTGCAGCACATCCCTAGTTTCTGCGAATTTTGCTGTTGTTACCATATTTCAGTTTTCCTGTGGATGTGTTACCTAACTGTATTAGGACTTAGGGACTTCTAAGAAATAAATTATCCAAATAAACGAACCACAGAGACACAGAGAACACAGAGAGAGGAAAAATATAGAGAGTTTTGGAACATTTTTTTATAGGACTTACGCAAAATATCTCTCAAACTCTGATTTCTCCGTGCCCTCTGTGCCTCTGCGGTTCGTTATTCCGTAACTCATGCGTAAGTCCTATTTTATTTGGAACTTCCTCACACCAGAAAGACACAGATGGATTTATCTGTGTCTCTCTTTGATTTCATTATCTTAAACTTTTCAGCTTACGAAAGATTCTGGAAGTAAACCTCTAGCGCTTCAGTCACTAACTGAGTCATCGGCTTACCTTGGCTTTCTGCTACTTCCTTTAACTTGCCATAAACTTCTTCTTTTAAATTTACCCGATGGCGCGATTTGTTTGCACCATTGGCTGTTTGGGGATCGTAGCTAGCAGCAAATTCGCGGATGGCATCAAAACCAACGCGATCGCAAAAATCACCAAAGCTTTCCTTTGATTTCCGAGATTTCTTAAAGTAAACAAAAATCGGCTCTAAGAAACTTTCTAAATCATTATGATGCAGCTTTTCTGTGTAAGGTTGCGCCAATCGAGTCTGATTTGGCGAACCCCCTAACCATAACTGGTAAGATTCTGGAGCGCTACCAACAAAGGCCAATTCTGCCAAGTAGGGACGAGCGCAACCGTTAGGGCATCCTGTCATTCTTACCACAAAATGTTCTTTTTGTAAACCTAATTTATCCAATAGAGCGCGAATCTGCTCCAAAATCCCCGGTATTGCCCGTTCTGATTCCGTGATTGCCAAACCACAAGTGGGTAAAGCCGGACAAGCCATTGCATACCGCACTAAAGGTTCGATTTTACTGGGTTCATCTCCAACACCGTGACGGCTGAGAATGTCTTGAATAGCTTCCTTGCTATCTGGTTCGATATCGTAAAAAATCACGTTTTGGTTCGATGTCAGGCGGATGGGTAAGTTGAACTGTTCGACAATTTCCCGCAAGGCGGTTTTCAGTTGAAACGAACCTTCATCCTTGACTCGACCATTTTCAATGGAAATTCCCAAGAATAGCTTGCCATCACCTTGTTCATTCCAGCCGAGGAAGTCGTGGAATTTAAACTCTGGTAGTGGTTTGAAGGCTTCGATTGATTTACCGAAATATTCTTCAACTTGGGCACGGAATTTATCTAAACCCCAATCGTTGATTAGATATTTTAATCTGGCGTGACGACGGTCGGTGCGATCGCCATAATCTCTCTGAGTAGCAACAATCGCTTTTACAATGTCGTAGACATCATCTTTCGCCACATAACCGATGGGGTCTGCTAACCTAGCGAAAGTTTCTTCTTTACCGTGTGTTCTGCCTAAGCCACCACCAGCAAAAATATTAAATCCTTCTAATTGCTTCTTATTATTGGTAATTACTACCAAAGTCAGGTCTTGGGAATACAAATCTACCGAATTATCCCCTGGCACCGTCACGCAAATTTTGAACTTGCGGGGCATATAATGCGTGCCATAAATCGGTTCTTCGTTGTCATGGATAATTGTGCCATTCCCGTTGCTTTGTCGCGCTGCTTTCACCTCTGGGTCTTCTTCAGCACTAATTGCCTTTTCACCATCTAGCCAAATTTCATAATAAGCACCCGTCTGTGCTGACAACAAATCAGCAATATTCTGGGCATATTCCCAAGCATACTGATACTCTGGGCGATTTTTAAAGGGGGCTGGTGGTGCCATGACGTTGCGGTTGATGTCACCGCAAGCTCCCAAAGTTGAACCCAGATTCTTGACAATGGTGGCGATCGCTGATTTCAGATTCTTCTTTAAAATACCGTGCAGTTGGAAACCTTGACGGGTAGTTGCTCGTAACGTGTGGTTGCCATACTCATCGGCTATTTTATCTAAAGCCAGATACAGCTGCGGCGGTACTAAACCACCAGGATTTTTTGTCCGCAGCATAAACTGGTAATCTTTTTCCTGTCCCTTAGTGCGGTTGTCGCGGTTATCCTGCTGATAAGAACCGTGAAACTTCAAAAGCTGCACCGCATTTTCAGTAAAATGGGTAGTATCTTGAAGAATTTCAGTTGCGACAGGTTCACGCAAAAAATTACTATTTTCCTTGATTCCTTCTACTTTGGAAGGCTTACGGCTAGCGATTGGGGAAGGAGCAGATTTAACCATTAGACTTGTATAGTATTCTCAATAAAGCATTACGTAGACACCGAATCAGCACCCTTCGGCTACTTGATCCCCGGTAATCCGGCCGGAATAATGAGGAATGATTTAATTTTACCACGGCAAAAGCCGGCTTTGTCAGTGATGTAACACTTAACAAAACCAGCTTTTGCGAGTAGTGAGTTTTGTTAGCGGTAGCGGGGCGTTTAGCCCGTGCTAAGTCCTGAGTACTTAAGTAAAGTATAGAGTGACCGAGGACTCAATAATTTTTTATTTGAAGCGATAGCCAAGACCGCCATTGATGGTAACAGCAGAAGCATCGCTATTTTGGTAGGCACCAAGTCCGACTTTAGCGTTAGTGTAGACAAGGAAATTGTTAGCAACTTCCGATTCAACACCAGCACCTAGCACTACTGAATCTCTGTTACCTATAGGAGTTGGTGAGCCATCTTTTTCTACAAAAGAATAACCGCCAGTTAAATAAGCGTTAGTTTTATTAGCGATAGGCACATCCACAGAAAGTTCTGGGATGATAGCACTTGTCTTATCACTCCAGAGAACATTACCACGTACAGAAAATGGCGTAGTTCCTAATTTCAGGCGACCTGTAACATTACCACCAAATGTGGCAGCATCATTGATACCTTCTCCGCCGCTAGTAACGCCAGCTGCAACACCAGCACCAACATAACTAGCATCAGTACCCTTTTTGGTTTCAGCAGAAGCTTGACCAGATGATAGAAAAAGAGGAGCAACTATTAAGGAAGATAATGCAGAAAATGTCACGAAAGACTTGAGTAAGCGTTTCATAATTTTTACCAAAATTTTTATTTTTTACTTGTATATTTCCAGTCGAAAATCATTTAACAATGTTCCAAATGTTTCCCAATTTTTATTAAATAAATGTTGCTAATGATGCATAATAGTTACAGGCTAAGTATCCCAGATAATCATAAATAAGCTGTTATAATTACATTCAATGTCTTTTCATCTGGGTTCTTTGTTCCAAAAATAGACGCTTTTAAAACTGTCACAATATTTGGAACTCAAACTATGTCGGAATAGTGTAAATAAAATATCCGACTAACATTTTTTGCCGAGCTTTTCACAGAGGATGAAAAACTCGGCTGTAGCATCTGTTGCAACAACCTATAGAGGGAATCTATAAAGTTAATTTTGAGCAGTTATTGTGGAGATTGAATAATGCTAACCGGTGCAAAAACGTTGTCTGGTTTGATGGGTTTATGTGTCGGTGATGCGTTGGGTGTGCCAGTGGAGTTTACTAGCCGTGCTGAACGAGTAAAATCTCCAGTGACAACGATGCAGGGTTATGGCACATGGAATCAACCACCAGGAACTTGGTCAGATGATAGTTCGTTAAGCTTTTGCCTAGCAGAATGCCTTTGTAGGGGGTATTCGTTGGATGCCATAGCCAATTCCTTCTGGCGCTGGTACAAGGAGGCTTACTGGACTCCCCGTGGCGATGTCTTTGATATTGGTCAAACTACCCACACAGCAATTATGCGTCTGAAACAGGGAGTTGTTCCCCATCAGGCGGGTGGGAAGGTTGAAAATAGTAATGGCAATGGTTCGTTGATGAGAATCTTGCCGATGGCTTATTGTCACCAAAACTTAACTTTAGGCGAATTGCTAGCGCGGGTGCATGATGTTTCAGCGATTACCCATGCTCATGCGCGATCGCAAATGTCCTGTGGAATTTATATTAGTATTGCAGTGGCGCTCCTAGAAGGGGCTGACCCCCAAACAGCTTATCTACAAGCATTGCAAGATATCCAAACAATTTATTCTGTCCGAGAATTTTTGTTAGAAAAGCCGCATTTTGGCAGAATTTTTAGTGGTGAGATTGCCAAGTTACCAGTTGAAGAGATTAATTCTGGTGGCTATGTGATTGATACTTTGGAGTCATCCCTGTGGTGTTTATTAAATAGTTCGTCTTATTCTGAGGCGGTGCTGAAAGCTGTCAACTTAGGCGGAGATGCCGATACTACTGCCGCCGTCACTGGTGGATTAGCGGGAATTTATTATGGGGTGGAAAATATTCCTCAAAAATGGATGAACCAAATTGCCCGTAGACAGGACATTATTTATTTGGCAGAGCGTTTTGCAAGGGCTGTCTACAGTTGAAGGGACTGGGGACTGGGTGAGAAGACAAAGGGAATAACCAATGCTCAATGCCCAATACCCAATGCCTAATCCTAAACCGTAGACAAAGAATAGACCTGACCATCAATCAGCAATCGTGTGATGCCTTTAGCTTGCAGATGAGTCCGAGCCTTATGGAGCATTTTACTATCAGGAACTTTAATTACGCGATCGCGCTTGGTAGAAAAGCGCTTGGCGACGCGATGATTATCAAATACCGGCAGAGTTCTTTGCTGAGTTTCCAGGCTGGGAATTTGTCCCAAATCACCAAAGTCCTTGAGAGGCCGGGTAATTAATTCCGAGGAACGGTCAATTACCAAATAACAAGTTTTCGGCAAATTGGCTATCGACAGAGGTAAAACTTGAACTGATGCTTCACCTGGCCTTCTTTTTGTGACTAAAGGTCTTTCGTCATCCAGCTCATCATCATCAAAGTCTTCTTCCTCAAAGTCGTCATCCTCTAAATCATCATCTTCTAAATCATCCAAATCCTCCGATTCATCTAGCAAATCTTCGCCTAGCATCTGCGCGATGACAGCCGCTCCTGGATGTTTATCCTTTAGCGGTGGAATGGAGATGCTGACTATTTCCGGCGGCTTTTGCTCTGGAGTTTCTAATTTCTCTGTAACTCGGAGCTTCGGTTTTTCTGCCGCCGAGGGGCGACGACGCACCCGTCTACTAGCAGCGAGTGATTCTGCCGTTTCCTCTGAGTAAACTTCCGGCTCTACACGAATTACCCGACGTGGCTGCGGCTCAACCTTTGTCACTTCCAACGGTGGGCTTTCGATGGGTGGAACTTCTATCTCCGGCTCCGGTTGAGTCAGCAATGGTAACTGCTCATAGCTTACCTGCGCCCTGCCTTCAGGAGTTCTCGCAGCCCGCTTTAAAGAGACTAAGTATTCATACTCATCCTCTGGCAAAGTGCTTTTGAGCAGGCGACTAATTGTCGAGTTACTCACACCATAGCGTTCTGCCAAAGTTGAGGTTGTTTCGGCAGTCTCTCGATATAACTTAAGAATTTCTTGCTTGTCAGAGTCTGTTAGTTTTCTCACGGTAGATACCAAAAATCTTTACTAAGCTCGTTTACGTCCACTGGTACGCCGCGTTCGTCTTAGTGATGCGTCATATTCTAAGACAGCGCCCATGCCAAATAACACCCCACTAAACACCCAAAACACTTCTAATATCTCCCCACTTTGATAGTTGGGGCCTTGGGCGTATTTAAACCACATATCTGCAATGTAAAGCGAAAAGGCCGCTGCTGCAATCATTCGCCAAGACTGGGAAACTCTTCCCCCCCAAAAGGCTAGTAGCAGAGTGGTAGCAATAATTAACAGAACTACATCGCTAACTACGTAAAACCAATTCAAAATAGCGACTAGCAGTTCTGAGGGTGTTTCCTGTTGCATAGAAATCCACCATGCCAACAAACTACCGAATACTGCAATTGCTAACACAATTAGCCACTGCCATTTTTCCAGATTGATTCGCCTGGAAGCCACAGCTAAAATCATGCCTGCGCCAAGTAATAGATAAGTGAGTACAAAAAATATATCGCCTACAGACACATCTGGTTCATCTTTTAACACTATTTCGGTATATCCGAAAATTATCCCCCCAACGAAATAGGAAAGCATACCTAACCCAATTAAGAGCCAGACATTTCGCCCACTGACGATTTGTGGACTCAGCCAGTTCCTCAAGCATAAGATACTGGCACCCAAATAAGCTAAAGCTTCAAAAATATTTGTACCAATCACATACCACTCGGCCCGGCTTTCTATGCCATCAGCTCCGGGAACTTTGGCACTAAACAACAAAAAGTATAGCAGTGCTAGTACGGCCCAGCCAATATTAGCTAAGACAATGTTCTGAGTATTGAAAATGGATTTAGAAAGGAACGAATTCTCGTAAGAGTTATTCATAGGAATTGACTATGTAGATGCACTCTGGCAGTATTTTGAGTTAAAGGACTGTATATATAGCAGTGTGTCTGCCGATAATACACAATCGGACACCAAAAGCAAGTACCAGTGGCCGGAATTTTGTTAAAATTTTCCATGCTACTGCCACAGTTTACCCAGTGGCGATTGATTTAGCCAACTGATAAATAGCAATCGCTCGGCTTCTGGCATATCTTCTAGCTTATAAATCACTTGTTTGGTAAAATTGCCATTGCCAAAATATGCTTTTCCTAATCGATGCAATTCTTGTAATAAAGTAACTACATGATTTTCCTGCCAATCAGGTATTTTGGCAGTTGGCAAAGGATTGGTAGATACCAAATATTTAACTGCTTCTAGGGAAGATGCTTGAGGAAATTGCTTTTGCTTTAATACTTCCGCAATATCTTTCTCAAATAATGCAGCTTGTTTAGCACCTAAAAACTCTTCAATGTCGATAGAAACACCCTGTAACAGCAAAATACTGGCTTGGACTAAAATCGCCGTTTTGCCATGACCACCTGTATCACTATCCAGCTGCTCTAAACGGATTTTACCCCAGACGCTAAAGCGTTCGGGTTCCTCCAGCAAAACACAGGCTTTACCCCGGTTATCCGTTAATTCTCTCCATAAGGCTCTAGCTTCTTCTTCTTGACTAGCTTTGAAAACACTAATCAAGCGAAAAGTCTGCCCTTGATAATTGAGGATCGGCACCTGCTGATCCTTTTTTGGGTGCTGAATGCTTGATATTTCAACATCCTGCCGTTTGAGAATAAACATGGCACTAGCAAATAACTCCTCACAGGGGCACTCTTAATATGGAATATATAATGGCATTTGGCAGTATCGCCAAGGCTGAAATTACCTAGCGTACTGTGAAAATGGGCCTAGCGATCGCCAGATTCTTCCCGAAGGTAGCCACCCAGAGGGCATTGGCGTTAACAGGCAAATAACCCCTTGACAACTCAATATATCTAAACCGATACTCCATCTGTTTCGTTTTTGGTGTAAATTGACTAGCTAGCGACTAGCATCTTAGCCTTGCTAGTGGTAAATCTGCAATTTTTGATTGCTTCTTGGTAAGTAAAGACGATATAATAGTGTAGGTGACTCCTTCAGGAGCCATTATTTTGTTTTGGGCGCGTAGCTCAGTGGATAGAGCAATTGCCTTCTAAGCAATCGGTCGCAGGTTCGAACCCTGCCGCGCTCGTTTTAACTCAATATGAACCCTCAAGCGGTGTGAAGTGATATGATGATTTCCGCGTTTGAGGGTTCGTTATTGCTGCATCATACCAAGAACAAAGGTGATATAGCGTTTCCTAGTCTAGTTAGGTACAGTAACAACAATGAGTAAACCAGCCTTCGATATCTTTTAAAGATACTTTATTAAAAGCTTCTTCAACGGCTTTCGCTAAATCTGGATAATTTTTGGCACCGATAGAACGTAGTATGTTCAGAGTTTTGGAACTAACTTTTGAGAGATAAATGCCTCAAATGTGAGTCCATCTGTTGCACCAATCAGACTAATTTGGGTAATTATACCTCTAAAACCGATAGCACCAATCAAGGAGACATTTTTTCCTCGCTTAATAGGACGTTCACCTCGCGCTTGCTTTCCTTTGGGCGCACGGGCAAATAGTCTTACTAAAGATAAATTTATGCCGGATTCATCAATAAAGATAAGATTTTTAGCTAGAATTCCTTGAACTTTTTGCCAAAATTCTACTCTTAATGATTGAACTCGGTCACTCTCTTTCTCGGTTGGGTATAGTGTTTTTTTTTGAGATTTAGGTTAAGAAGACGCAGCATCCTATCTAGAGTTGAGCGACCAATCAAGACTCCCGTTTTCTGTTCTAACAGCAGACGAAGTTCATCCAAGGTTGCATCATTATTATCTGACACAATTGACGACAAAACGTTTAACTCTTCCTGCGAGAGCTTTCTTGGTGTTTGTTGTGTGCGAATCTTGGGCGAAATACTCACAGTCTTTCGATATTGTTTCAGTAATTTTTCAACAAGACTTTAGAGGCTGTTTGAAAAGTCGGAGAGATGGTAAAAAAGCTCTCTCAGTATACGCTGTGAATAGATAGTAGACAGCACCGAGAGAGCAACATGAGTAAAGCATACCCCAGCAATCTGACCCGTGTTCAATATGAATTTCTCAGTGACATGATTCCAGAACAAAAACCCGGTGGTCGGAAGCGTGAAGTTGATATGTGGGAAGTTCTGAACGCAATTTTTTATGTCCTAGTAGAAGGAGTTAGATGGCGATGCCTACGGCGGGCTACGCCTACGCTACCGGGTGACTTTCCCGTCTGGCAAACGGTATACAACTATTTTCGTAAATGGCGCAAAGACGGAACGTGGTTGAAAATTCACGATAGTCTGCGTCAGTGGACAAGGATTGAGCAGGAGCGCCATCGAAGCCCTATCTACCTTGCCATGATCCGGATCATGGTAAGACGATTAGCATCCCACCCTCGCGCACCAAAAAAGACAAGAAGGATACTAAAACGTACTCATCCTTCCAAACGACCCCATGTTTCTACAGCTAAAATTCTATCCCAAAAATAATACCTAAAAACAGACACCTTGAAAGGGCTGATCCTAAAATATATGAGAGGTTGCAAAATGTATTGTGAAATCAGTATTTTAAAAATGCCTAAAAACCAAGCTAAAAACATATTTAATAGAGGAAGAAGGTTTAGGAAATAATTATTGAGCCTACACCTTCTTCCTAAATCAAGTTCAGCCTATTCTAAAGTCTTTTTTACTTCATCTTTAATGTTTTCAGCAGTGTGACGAACTTGGGCTTCAGCTTGTTTAGCTTTACCTTCAGCTTTGTCATTAGGGTTACCAGTTACTTCACCAACTGCTTCTTGTACTTTTCCTTCGACGTTCTTTGCAAAAGCCTTTGCTCTATCTTCGATACTCATATACTTTTTTCCTTATCTTAACTAGTGATTATCTATTGCTTGCTAAGAAAGCGTTGCAATGTTTATATATTACTTTTAGACAAGTTTTAATTCTTCTATCTGACGATGTTTTTATTAAGAATATTTGTGTCCATTGTACATAGTTATTTAAAGGTGAAATTCATCTTGAAGAATTCAAGTAATATCCAAAAGATAGAAAGGATTTATTCTATGGTTCTATCTTCAGATAAAATCATTTGCTACTTTAGCTAAATAATGATGCAGATGTCTACCCTAAATTAGCGGTTAAGAAATACTCAGAATGTGAAAAACGCAACTTGAGTTAGCAGTATTGCTGCACAAACAAGTAATTTATTATACTTTAAGCGCTTATAAACATCTGGCACAACAAAATAGTCGAGATATAAGAAAATATTCTAATACTGCTTACTTAAAGGGAAAAGGAGCGGAAGACCTGATATATAAGGCTTTTCCCCTTTAAGCTTTTCCTTTCCCCCAAAACTCGACGTTCCAAAAAAGTGGTGTTGTCACAAATCTTAGGCGGAAAGAAACATAATTTTTCAAATTTTAACTGAAGAGTAGTTTAGCTAGTGCAAGAAAGCAGAGAGAATTCTGTAGATTTTTCTGCGGCTTTCCGCAGGGTACGAAACTTCAAAGAGACAGCAGGAAAGAAAGCTTGATTTACAAGCTTTTGTTACCTTTTTAAACTGGATAGTTATTTATGCCATACCGCACTAGTAAAACTTGTAACTAATTTCTCACTAAAGACAGCAGGAACAAGTATTTACGTTTATTTCTATTTATCAAGGTAACGCGATGTGCGACTTATTGTTTCGTTACACAAGTCGGGTGTATGAACGATTGAAAAGAAAATTCCCACAATCCGCACTGGAGCGAGAAAATCGTTACCAGTGAGTGGAATGAGGGAAAAATGTTTTCTATAGAAGAGTTTATCATTGCCGTATTTTGCTGTGTTGACGATGTGCTGATTGAAATCACCCAGGTATACCCAATTAAGAGACGAGGTTTTGCTCCAAGTTTAAGGGAGAGTGAAGTTTTAACAATGGAAGTAGTGGCAGAGTTTTTGGGAATAGATGCTGACAAAGACATTTGGAAATACTTTCACCGTCATTGGTTAGGGCTATTTCCTCAGTTAAAGAGTCGCTATGCTTTTATTCGTCAAGCAGCTAATTGTTGGCAGTACAAAGAACTGTTACAACAAAAATTAGCACAGATTTTAGGGGCATTTTCTGAGCAACTTCATTTAATTGATGGATTACCAATACCTTTGTGTGGCTTCAGTCGCGCTCCCAACTGCCGGAGTTTTAAATCCCAAGCAGATTATGGCTTTTGTGCTGCCAAGCAACAGACGTATTATGGGTTTCATGGGCATTTAATCATTAGTGGCACAGGAGTTATTAGTGGGTTTACTCTCACTCCGGCAAATGGCAGTGAACGAGAAGCACTTTGGGATTTAATCACGCGAGTTAAAGGTTTATTAATCGGAGATAAGGGATACTTAAGTCAGTTTTTGTCAGGAGAACTTGAAGGAATGGGTATTAATTTACAAACCCCTCTGCGTTCTAATATGTCTGACTCTCGTAGCCAATCTTCAGTTCGATTAATGCAACGCTTTCGTCGCCTCATTGAAACAGTTATTGGTCAATTAGTTGAGAGATTTCATATAGAGAAGATTCGAGCGAGAGATATGTGGCATCTTACCAGTCGTCTCAATCGCAAGATTTTAGCTCATACTGTCTGTTTCTGGCTTAATCGCCACAATTGTGACCCGCTTCAGTTCGACGATCTTGTTACAGAATATTAA

Protein sequences of DBSCAN-SWA_6

>NZ_CP046703|6496978:6567177|6550745_6551048_-|WP_114081110.1|DBSCAN-SWA
MQLTPQEKDKLLIFTAALLAERRKGRGLKLNYPEAIAYISAAILEGARDGQTVAELMSYGTTLLTRDDVMEGISEMVHDVQVEATFPDGTKLVTVHNPIR
>NZ_CP046703|6496978:6567177|6541257_6541566_+|WP_114085535.1|DBSCAN-SWA
MAIPNKEVKSNTDILDNRRTQTRIQVRIPKDLHEEPVISRLVSHYGITVIIADAQVSANVPQYSCFDLELRGTVSQIESALTYLDELDLEVLHQSSPEEDGW
>NZ_CP046703|6496978:6567177|6537324_6537930_+|WP_114085538.1|DBSCAN-SWA
MLGKFFQKPGKEEGERVPPGQHLAKGFPVLTYGATPQVSIEEWEFRVWGLAKPATFSWSDFMALPQHEFTADFHCVTRWSKLDVKWTGIKVTDFMDLIELDPKVAHIMEHCYGGYTTNISVEDFIREENFFAFKVFGEDLPSEHGGPMRLVVPHLYAWKSAKWINGLEFLAGEELGFWERNGYHRRGEPWAEERYSNAFGF
>NZ_CP046703|6496978:6567177|6560526_6561525_-|WP_147262571.1|transposase|DBSCAN-SWA
MRKLTDSDKQEILKLYRETAETTSTLAERYGVSNSTISRLLKSTLPEDEYEYLVSLKRAARTPEGRAQVSYEQLPLLTQPEPEIEVPPIESPPLEVTKVEPQPRRVIRVEPEVYSEETAESLAASRRVRRRPSAAEKPKLRVTEKLETPEQKPPEIVSISIPPLKDKHPGAAVIAQMLGEDLLDESEDLDDLEDDDLEDDDFEEEDFDDDELDDERPLVTKRRPGEASVQVLPLSIANLPKTCYLVIDRSSELITRPLKDFGDLGQIPSLETQQRTLPVFDNHRVAKRFSTKRDRVIKVPDSKMLHKARTHLQAKGITRLLIDGQVYSLSTV
>NZ_CP046703|6496978:6567177|6536875_6537049_+|WP_012407602.1|DBSCAN-SWA
MAVPKKKTSKSKRDKRRATWRHKAVVEAQKALSLGKSILTGRSTFVYPTAEEEEEES
>NZ_CP046703|6496978:6567177|6566283_6567177_+|WP_114085155.1|transposase|DBSCAN-SWA
MFSIEEFIIAVFCCVDDVLIEITQVYPIKRRGFAPSLRESEVLTMEVVAEFLGIDADKDIWKYFHRHWLGLFPQLKSRYAFIRQAANCWQYKELLQQKLAQILGAFSEQLHLIDGLPIPLCGFSRAPNCRSFKSQADYGFCAAKQQTYYGFHGHLIISGTGVISGFTLTPANGSEREALWDLITRVKGLLIGDKGYLSQFLSGELEGMGINLQTPLRSNMSDSRSQSSVRLMQRFRRLIETVIGQLVERFHIEKIRARDMWHLTSRLNRKILAHTVCFWLNRHNCDPLQFDDLVTEY
>NZ_CP046703|6496978:6567177|6513901_6515383_-|WP_114085555.1|DBSCAN-SWA
MVNAAQARQTKERFAQPEEQLTYELGKAVQELPPLYTRLLAGTMSAIVFGAIAWAYFSQIDEVATAPGELIASTQVRPVTSLGGGSIVGVKVQEGDRVTKGQILIQKDPDLQITDVSRLAKSTRLIQDDLQRLDAERLGGKTTGTKLQDELLTSRLQDYQARQAGAEAEANRQIALINQAKVRLTRLQENLANAKSSFANAKTNLANADSIRIKIESNLALAQEREKSLRTLITTGAVPRVDYLDAQERLTRAKTEITRSQDEVTNAQNRITEAQDKVTSLEKDIAAQAQEIRQAEQAYNSARSQAQRVASERQSEILTQFNKRKEELTTVQGQLEQARKQQALETIEAPVAGTIYRVKATKGPVQSGEELLSILPEGEEMLLEVKVLNRDIGFIRQGMKAKVKMATFPFQEFGVVEGEVMQVSPNAIIDKELGLVFPTRIKLNKHSVNVRGQEVEFTPGMSATGEIVTRKKSILTFITEPVTRRFNEAFSVR
>NZ_CP046703|6496978:6567177|6562536_6563196_-|WP_114085157.1|DBSCAN-SWA
MFILKRQDVEISSIQHPKKDQQVPILNYQGQTFRLISVFKASQEEEARALWRELTDNRGKACVLLEEPERFSVWGKIRLEQLDSDTGGHGKTAILVQASILLLQGVSIDIEEFLGAKQAALFEKDIAEVLKQKQFPQASSLEAVKYLVSTNPLPTAKIPDWQENHVVTLLQELHRLGKAYFGNGNFTKQVIYKLEDMPEAERLLFISWLNQSPLGKLWQ
>NZ_CP046703|6496978:6567177|6517667_6518594_+|WP_114085551.1|DBSCAN-SWA
MSDENQFDVFLCHNSKDKPEVIEIANELTRQGIKPWLDKWELRPGLGWQVLLEEQIENIKSAAVFVGSSGLGPWQSQEMRAFLNEFVERKCPVIPVLLGNTPHQPKLPIFLRGNTWVDFRTDTEAMEQLIWGITGRKPKLQQVIQVDNLSSEKGVNYTRLRDLLAAGKWKEADEETLAVMLKASSREKEGWFDIESIKNFPCTDLRTIDQLWVQHSDGRFGFSVQKNIYLSVGGKADGEYYKEVWEKFGDHVGWKVKGSWIDYSSVDFNISAPEGHLPRMSGEGYLLFGIGGVGRISFLASRLVKCNI
>NZ_CP046703|6496978:6567177|6531127_6532897_+|WP_114085542.1|DBSCAN-SWA
MAKNEANNSALKIIPLGGLHEIGKNTCLFEYDDEIILLDAGLAFPTEAMHGVNIVLPDTTYLRENRHKIKGMIVTHGHEDHIGGIAFHLKQFDIPVIYGPRLAMAMLEGKLEEAGVRDRTEIRTVLPRDVVRIGKNFLVEYIRNTHSIADSFTVAIHTPLGVVIHTGDFKIDHTPVDGEKFDLQRLAEHGEKGVLCLLSDSTNAEIPGFTPSERSVYPNLERVFSQATGRLFVTTFASSVHRINMILDIAKKQNRVVTVVGRSMLNLIAHARNLGYIKCEDNLLQPLHAVRNLPDEKVLVLTTGSQGETMAAMTRIANKEHPHIKIRQGDTVVFSANPIPGNTIAVVNTIDKLMIQGAKVVYGRDKGIHVSGHGCQEEQKLMIALTRPKFFVPFHGEHRMLVKHAETAQSMGIPAENMIIIQNGDIVELTEDAIRVAGKVPSGIELVDTTSSGMVSAKVLQERQRMASEGIITIAAAIDWNGKLLAKPETHLRGVVTTVERSLLQTWVKQRIEEILTVRWTEFAPGGEAADIDWGGLQGTLERELQRSIRRELQCQPSVTLLMQIPDEPPVKVADGRRRRTRTAAQVAS
>NZ_CP046703|6496978:6567177|6503452_6506152_+|WP_114084580.1|DBSCAN-SWA
MASRENSKTDSQATSELKILDNESLRLKVLASLPWNQPPLCWLTPEQQSQLENECQTRQYRLGEKIWSNDVGRYQFLIVAGKVRLREEGVGKPLAALEVGDWFGDLQKLSADFKAVAASKEVIVVCWDTALWTEFSNPQIQEFWQVLPVDMEGERETFSFSSTPSVTVSDGTSSPHSLQPQKRLPAANLIISNYPFVASWNTAAACLTMVAQQLENSVQLEWVQRQLRGQRPKQVVEAGEKLGLVLRRLQVSWGELRQLSFPALLLWNSDSPQSPSWVVAYGVKGDRLIIANPLNPDRICESLPQSIVEASWDGRLWQVELISKQETFNLSWFTPAVWKYKGLLTEVLLASFTLQLLGLTTPLITQVVIDKVMVQGSLPTLDVMAIALLCVAIFESVLGILRLFIFTHTARRLDLSLSAQLFRHLMRLPLAYFESRRVGDTVARVQELEQIRQFLTGTALTVILDSIFAVVYLALMFYYNVPLTFVALAVLPLFATLTIVATPILRNWLNETFNRSADSQSFLVETITGIHSVKAHAAEPVARDRWEGLFARFIRTGFKASTTSNISSNIGDFLTNFSTMLILWFGAKLVIEQKLTIGQLVAFQMLSGRVTGPLLRLVQLWQTLQQVLLSVDRIGDILNVSPEAELGTGLVLPPLKGQVTFEQVFFRYRPNFEAILRGISFNAEPGQFVGIVGRSGSGKSTLSKLLQRLYQIESGRILIDGFDIKSADLASLRQQVSVVLQEDFLFNGSILENITLGTPDITAEQVVEAARLAVAHDFISQLPYGYETNVGERGTALSGGQRQRIALARLFLSQAPILVLDEATSALDSETEQQVLQNLQKVSANRTVFLIAHRFAPLKRADLILVLEQGVIAERGTHSELLQQKGLYWSLYQRQQANI
>NZ_CP046703|6496978:6567177|6549873_6550416_-|WP_114081112.1|DBSCAN-SWA
MNMEWYNEPPVWEVKDEAITIASGAKTDFWRETHYGFIRDNGHFFYQKIQGDFIAEVKISGQYQDLYDQAGLMIRLDELNWLKCGIEFVDGVQQISAVVTRNYSDWSVIPMPQNPSLIWLRVTRRDTAIEVEYSLNGTEYTMLRLAYLTQTETVSVGVMCASPEGNGFQMRFEKFQIRSL
>NZ_CP046703|6496978:6567177|6501509_6502307_+|WP_114084578.1|DBSCAN-SWA
MSSLIDSVNPWLVAVVLNTILLGLAWIAPKKLLTPAGSFHAWFLAILIWVTLGWQGYTVVMFYFLVGSGVTRIGMAQKEAEGIAEKRSGARGPENVWGSALTGALCALGVGIINSGFLVPSSQSLVPNLQSLLLLGYVASFSTKLADTTASEVGKAYGKSTFLITTLKPVPRGTEGAVSLEGTLAGIVASVAIAFVGWGVGLIDLLGVAWCVLAAFIATNLESVIGATLQSKYTWLTNEVVNIFNTLIGAIAAVLLSWTWVNIIK
>NZ_CP046703|6496978:6567177|6520766_6521750_+|WP_114085559.1|DBSCAN-SWA
MIQFRIQPDSEIPASTQLFNQIRFAIASRQYPPAYKLPSTRALAMQTGLHRNTISKVYRQLEEDGFVESMAGSGIYVRAQGHEGGSRLQSPILKQNPDAYQVVQQALDDLLSQGCSLNQARELFLAEIDWRLRCSARVLVAVPSYDMGAGELMVYELERSLKIPVQLVAMEELTAVLDKTTSATVVTSRYFISNVEAIAAPKAARVIPLDIYDYSKELSLLKTLPKENCVGIVSLSSGIARAAEVILHGLRGDELLVMTSQPKDAYKLQAMVKRAEVIISDQASFAAVQAAVQASDEDIIRPPKLIKVENYIGTNSINLLKRELGLS
>NZ_CP046703|6496978:6567177|6516550_6516928_-|WP_114085553.1|DBSCAN-SWA
MFTRSELEIKTIKELLDLCRRYGVKPTGNAGYKTSYIVTLMAFPLLALQQMKLGKGLKSPNFNAIQVISSAIEEMNSPTDEQTALIRITLEGRKMSYPDRYQQENLLNLHKAKMSLEQAIDFLSQ
>NZ_CP046703|6496978:6567177|6548148_6549864_-|WP_114081113.1|DBSCAN-SWA
MSYRMDRRAYAETYGPTVGDRIRLADTELFIEVEQDFTTYGDEVKFGGGKVIRDGMGQSPISNADGAVDLVITNALILDWWGIVKADIGIKDGKIFKIGKAGNPYIQDNVDIIIGPGTEALAGEGMILTAGGIDAHIHFICPQQIEVAIASGITTMIGGGTGPATGTNATTCTPGPWNIYRMLQAADAFPVNLGFLGKGNASQPQGLVEQVNAGAMGLKLHEDWGTTPAAIDTCLSIADEYDVQVAIHTDTLNEAGFVEDTIAAFKNRVIHTYHTEGAGGGHAPDIIKVCGQANVLPSSTNPTRPYTLNTLDEHLDMLMVCHHLDPAIAEDVAFAESRIRRETIAAEDILHDLGAFSMISSDSQAMGRVGEVIIRTWQTSHKMKVQRGILNPQGDEQKADNFRAKRYVSKYTINPAIAHGIAQYVGSVEEGKLADLCLWHPAFFGVKPEIVIKGGMIAWSQMGDANASIPTPQPVYMRPMFGSFAGARHATSLTFVSQAALENEIPSQLGLQKAAVAVSGTRQLSKRDMKLNDALPHIEVDPETYQVRADGELLICEPATVLPMAQRYFLF
>NZ_CP046703|6496978:6567177|6496978_6498370_+|WP_114084573.1|tRNA|DBSCAN-SWA
MVNRRTAEILRSGQPDESLQVQGWVRTKRESKGFAFIEVNDGSSLANLQVVINQDLPDYEAILKKLNTGAAVEATGVLVASLGKGQRIELKAESVKVYGEADPDTYPLQKKRHSFEFLRTIGHLRSRTNSFGAVFRVRNACSAAIHQFFQERGFLWVHTPIITASDCEGAGELFSVTSLDLKNIPRTENQAVDYSQDFFAKPTYLTVSGQLEAEVMAMAFSNVYTFGPTFRAENSNTSRHLAEFWMVEPEMAFCDLEGDMDLAEAFLKHIFKYVLETCPEDMEFFNERIDKSVLATAENIINNQFERLTYTEAIKVLEKADVKFEYPVSWGLDLQSEHERYLAEQQFKKPVIVTDYPAQIKAFYMRLNDDEKTVRAMDILAPKIGEIVGGSQREERLEVLERRVLAQGLKPEDLWWYLDLRRYGTVPHAGFGLGFERLVQFMTGMGNIRDVIPFPRTPQSAEF
>NZ_CP046703|6496978:6567177|6498495_6498756_+|WP_114084574.1|DBSCAN-SWA
MIYNRQVFKLWGSTKIQLKTFIISLKDQIIGKFRQNARISGRVVLDEKASSVKYEVVVEKIKRSLLVWRVSPSTTGKAILTLWIHI
>NZ_CP046703|6496978:6567177|6528798_6529836_+|WP_114085544.1|DBSCAN-SWA
MSKSYRLAILGATGAVGTELLELLESRNFPIADLKLLASERSAGRSLRFKGENIPVEPVSDRAFENVDIVLASAGGSTSKTWAAVAVAKGAVVIDNSSAFRMNPEVPLIVPEVNPQAAANHQGIIANPNCTTILMTVAVWPLHQVKPVQRIVASTYQSASGAGARAMAEVKAQTSAILQGQPPVAEVLPYPLAFNLFPHNSPLNDLGYCEEEMKMVNETRKIFGTQQIRITATCIRVPVLRAHSEAINLEFETPFSAEEAREILNSSPGVKLVEDWETNHFPMPIEATGRDEVLVGRIRQDISHPCGLELWLCGDQIRKGAALNAIQIAELLVEKNLLKPLAISH
>NZ_CP046703|6496978:6567177|6523085_6524006_-|WP_114085548.1|DBSCAN-SWA
MPYIKVRGVDHYYEWVKKPSGSLVKPVMVFMHGWAGSARYWQNTANALSEQFDCLLYDMRGFGRSGGKPTIGQASEAVADSKSPQEESEAIRELSYELEEYADDLAALLDGLHLQRVYINAHSMGASVATLFFNRYPQRVERGILTCSGIFEYDEKSFSAFHKFGGYVVKFRPKWLSKIPFVDRMFMARFLYSSIPHSERQAFLQDFLEADYDAALGTIFTSVSKAQSEVMPLEFAKLTVPTLLVAGEYDKIIPAEMGRKAAGLNDKVKFVMIPNTAHFPMLEDAPTYMQVVQEFLQINIPQPQVK
>NZ_CP046703|6496978:6567177|6502721_6503504_+|WP_114084579.1|DBSCAN-SWA
MESLSFLTINDQIISIEEAVKYLQASGKLGQFIGDILRQHVIEQEIRTRDDIEIGTAITEQSIIDFRLKNQLTDPQSFQEWLKTNNTDYAAFHTSVTFGYKLEKLKAVVTEAKIQEYFIERKIFLDRVVLSRIVVNNRELADELQTQIEEGGSFEQLAKEYSLSDDRIVNGMMGIVSRGSMPDILRAAIDVASPGQLIGPIEIVGKDSPQGEGPYGLFRVEQFLPASLEDTQLKQALQNELFEKWLAEKIQKLTVKLQVS
>NZ_CP046703|6496978:6567177|6543477_6543789_+|WP_012407590.1|DBSCAN-SWA
MAALSLSVSTVKPLSDRVFVKVNASEEKTAGGLYLPDTAKEKPQVGEVVALGPGKRNEDGSRQELEIKVGDKVLYSKYAGTDIKLGTEEYVLLSEKDILAVVI
>NZ_CP046703|6496978:6567177|6554668_6555418_-|WP_114085164.1|DBSCAN-SWA
MSQLQRIAIAPSQFQQGQILLTKEQQHYLGRVLRLREGDRFIAMDGKGKWWLAQLAGEQAQVLEALLVETELPVSITLMVALPKGNGFDEVVRCCTELGVTCIAPVLSDRTLLDPSPQKLERWRRIAAEAAEQSERSFVPTILEPVAFNTGLSLVIGHLSFANSQQYICEARGEFPHLKHCLQHKGQMTNDKGQETIVIATGPEGGWTTQEIENAIASGFQPVSLGRRILRAVTAPVVALSLITASCEV
>NZ_CP046703|6496978:6567177|6534159_6536040_-|WP_114085540.1|DBSCAN-SWA
MANYWAIAIGINHYQLFQPLSCAQADAEALEDFLVTEAGFLPKHCLLMTDTSPPIGDRSTYPTKENILLLLEDLAATSWQPEDYLWLFFSGYGVNYKGKDYLMPAEGNPELVQETGIELRSLMQSLQLADLNVLLLLDINRAFGTQADAPVGEETIELAQELQLATILSCQPEQFSHESSELGHGFFTAALLEALRSGNGSNLSDLESYLSLVMPKLCHHHWRPVQNPATIIPSRAQIILPELAIENGFEANPVIYPEESFAVALAAPPLDDYPRTSAQRGRWGEATVNSSQQVKAYKVEKPKAQPVQESATSLVSQPMAETSLGANPKGRFIPNSSKGYVSRLPSNQPSLPFWKQFILWGGGSLLVAGLIAVVFLRNQETFRIKQISTASPSATASDRQIIENLPSDSTSVVRLNNQSSAQIISSSESKKRNQAVLDLAKMSLRQTQASDLSMAIATARKIKPGEPLYEQAQENIKIWSRMILDLAEGRAKQRQYASAIAAARLITKDEAPYAKAQAAINLWRLEGKQYVSNKTLLDAANALIKSGQASTYNRAIEVAKKVPAGQPGFDSAQKSINKWSEKILDLAKSRAAEGDRSAAIATAALVPEETAAYEDAQDAIQKWQKK
>NZ_CP046703|6496978:6567177|6524117_6525458_-|WP_114085547.1|protease|DBSCAN-SWA
MSKYDSHLKCSFCGKSQEQVRKLIAGPGVYICDECVDLCNEILDEELLDTNGAAAQPAPRAEPPQKRRTQSSSISFNQIPKPREIKKYLDEHVIGQDEAKKVLSVAVYNHYKRLAVIQSKASGKGGADDAVELQKSNILLIGPTGCGKTLLAQTLAKILDVPFAVADATTLTEAGYVGEDVENILLRLLQVADLDIEEAQRGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKMLEGTIANVPPQGGRKHPYQDCIQIDTSNILFVCGGAFVGLEKVVDQRVGKKAIGFVQPGEGQTKEKRAADTLRHLAPDDLVKFGMIPEFIGRVPMVAVVDPLDEEALMAILTQPRSALVKQYQKLLKMDNVQLDFKPDALRAIAQEAYRRKTGARALRGIVEELMLDVMYELPSRKDVTRCTVTREMVEKRSTAELIIHPSSLPKPESA
>NZ_CP046703|6496978:6567177|6558580_6559120_-|WP_114085161.1|DBSCAN-SWA
MKRLLKSFVTFSALSSLIVAPLFLSSGQASAETKKGTDASYVGAGVAAGVTSGGEGINDAATFGGNVTGRLKLGTTPFSVRGNVLWSDKTSAIIPELSVDVPIANKTNAYLTGGYSFVEKDGSPTPIGNRDSVVLGAGVESEVANNFLVYTNAKVGLGAYQNSDASAVTINGGLGYRFK
>NZ_CP046703|6496978:6567177|6555431_6556076_-|WP_114085163.1|DBSCAN-SWA
MVTTAKFAETRDVLQNISWQTFKAMLADMGSERNKRLAYDNGIVEIMTPLMPHENSNRLIEGFVLVLCEEFGLEVKSAGSLTMTRDDLEQGGEPDSSYYIQNELLVRNKENIDLNTDPPPDIVLEVEYSRSKIDKLSLYASMEVPEFWRYNGNVLRIYTLKNGQYSQSDRSPTFAPVRLTEIPRFIQESKKVGQIAATRAFRTWVRQQISTAGQ
>NZ_CP046703|6496978:6567177|6543890_6545525_+|WP_012407589.1|DBSCAN-SWA
MAKRIIYNENARRALERGIDILAEAVAVTLGPKGRNVVLEKKFGAPQIVNDGVTIAKEIELEDHIENTGVALIRQAASKTNDAAGDGTTTATVLAHAIVKEGLRNVAAGANAISLKRGIDKATAFLVDKIKEHARPVEDSKAIAQVGAISAGNDEEVGQMIAQAMDKVGKEGVISLEEGKSMFTELEITEGMRFDKGYISPYFATDPERMEAVFDEPFILLTDKKIALVQDLVPVLEQVARAGRPLVIIAEDIEKEALATLVVNRLRGVLNVAAVKAPGFGDRRKALLEDIAVLTGGQLITEDAGLKLDNTKLDSLGKARRITITKDSTTIVAEGNEAAVKARVEQIRRQIDETESSYDKEKLQERLAKLSGGVAVVKVGAATETEMKDKKLRLEDAINATKAAVEEGIVPGGGTTLAHLAPELEVWAKSNLKDEELIGALIVVRALPAPLKRIAENAGQNGAVIAERVKEKEFNVGYNAATNEFVDLLAAGIVDPAKVTRSALQNAASIAGMVLTTECIIVDKPEPKDGAPAGAGAGGGDFDY
>NZ_CP046703|6496978:6567177|6561546_6562398_-|WP_012407575.1|DBSCAN-SWA
MNNSYENSFLSKSIFNTQNIVLANIGWAVLALLYFLLFSAKVPGADGIESRAEWYVIGTNIFEALAYLGASILCLRNWLSPQIVSGRNVWLLIGLGMLSYFVGGIIFGYTEIVLKDEPDVSVGDIFFVLTYLLLGAGMILAVASRRINLEKWQWLIVLAIAVFGSLLAWWISMQQETPSELLVAILNWFYVVSDVVLLIIATTLLLAFWGGRVSQSWRMIAAAAFSLYIADMWFKYAQGPNYQSGEILEVFWVFSGVLFGMGAVLEYDASLRRTRRTSGRKRA
>NZ_CP046703|6496978:6567177|6500336_6500768_-|WP_114084577.1|DBSCAN-SWA
MSQTLFHLAFPVTDIAQTKVYYVDGLGCIPGRENHHALILNLYGHQLVAHITKEPLIPQHSIYPRHFGLIFTQERDWQDLLERAQQQQLLFREETKNRFVGSPLEHRTFFLEDPFYNLMEFKYYRHPEAIFGSYEHTQIGDRT
>NZ_CP046703|6496978:6567177|6539582_6540722_-|WP_114085536.1|DBSCAN-SWA
MTSQSSRSGKILVVDDSPDNVFLIKTILEEEGYTISTAENGISALAELKASPCDLVLLDLMMPDMDGYEVTKHIRGDMKLPQYIPILLITAHDAPNVAHGLDLGADDFIRKPVTVDELLARVRSLLRLKHSMDERDEIARQREDFVSRLTHDLRTPLVAADRMLMLFQQGALGTLSPQMQEVITIMARSNINLLTMVNTLLEVYRFEAGRKSLAFQPVNLGRLLEEVTGELAPLAQAKTLSLNLDFTEESNTVMGDRLELHRLFTNLIGNAIKFTDSGSVTIRFTSQRQLDKSSQSQLSGKSNPVEYISIAIADTGPGIPTEEQSTIFERFRQGSHKSSGSGLGLYLARRIVEAHQGIILLNSELGKGSVFIVLLPATT
>NZ_CP046703|6496978:6567177|6499652_6500285_+|WP_114084576.1|DBSCAN-SWA
MNTENQQRNPVLLVHGIDDRGAVFHKMAGYLGLQGWSVYSLDLVPNNGDVGLDKLAKQVADYVTDTFAPEQELDLIGFSMGGIVSRYYIQRLGGINRIQRFITISSPHNGTVVAYGSQRPGCVQMRPDSIFLKDLNSDAVILEQLDFTSIWTPYDLMIVPANSSQMPVGSEVIVPVPLHPWMLTDPRSLAAVKAALTKPIKLPFLKKASS
>NZ_CP046703|6496978:6567177|6529962_6530847_+|WP_114085543.1|DBSCAN-SWA
MGDFGNVLTAMITPFKADGSVDYGVAAELAVHLANNGTDTLVMCGTTGESPTLSWDEEYQLFVEVLQSVAGKAKVIAGCGSNSTKEAIAATQKASKIGVHGSLQVVPYYNKPPQAGLEAHFQAIAQACPDLPLLLYNVPGRTGQNLQPETVARLAEVSNIVGIKESTGSIDQASEIRRLTPKEFHIYSGDDYMTLPLLAIGAKGVVSVASHLVGNQLQQMIQAFSAGKIEVASEIHLQLFPLFKALFLTSNPIPVKKALKLQGWEVGSTRPPLCEADLEVSQKLEAVLKELSLI
>NZ_CP046703|6496978:6567177|6536240_6536723_+|WP_114085539.1|DBSCAN-SWA
MSKIAAHLPSSITPFSVISQIARRIRIVPLLILLISTVPAWFLTEAIAPQVVRAYTARVDLAIDRLPEENYETVLRRAEAAARAAAQRSFDQDILVTDVSIIVSVQNFGAIAPVLALDVSRPQWRSRPDAQNWATYFKTARSLLFFDNSSTAANGVSSKK
>NZ_CP046703|6496978:6567177|6525467_6526166_-|WP_114085546.1|DBSCAN-SWA
MFVSQSGNYPISNQSRININSQLNSPSNIVPMVVEQSGMGERAFDIYSRLLRERIIFLGTPIDDAVANSIVAQLLFLDSEDSEKDIQMYVNSPGGSVYAGMAIYDTIQQIRPDVVTICFGLAASMGAFLLTAGAAGKRMSLPDSRIMIHQPLGGAQGQAIDIEIQAREILYVKAKLNQLMAHHTGQPLERIEADTERDFFMSAEEAKNYGLIDQVISRQNLPTAGENVTILK
>NZ_CP046703|6496978:6567177|6511832_6513719_+|WP_114085556.1|DBSCAN-SWA
MFNDNTNNNLFSTNKSLNFTSISSLDTFNTKNDTSFNLSGRSSYNSADSHVQLLNNSNYENSSNATTNAFTTQSYNSNNGYGLINAAAAVAKATNQNTFADVPDLGGNNWGADLVKAPEVWAQGYTGKGVVVAVIDTGVDYNHEDLKNNIWTNTKEIAGNGIDDDGNGYIDDNYGWNFADQNNNTLDNNGHGTHVSGTIAGENNNYGVTGIAYNAKIMPVKVLNESGSGSYSSISKGIRYAVDNGANVINLSLGGTSSNRTLESAINYATSKGVIVVMAAGNDGESEPDYPARYASKSGIAVGAVDKNNNMADFSNRSGTNQISYVTAPGVKVYSSVPNNQYATYSGTSMATPHVAGVVALMLSANPSLTDAQVRQIVAETSENSTQSTNSSLNISNVSSLAKQVISTTGYADTAANSSQITTSSLNISNISSLAKQVISGNNLLHIDAQTKNYLTPETIASFNNSDVASLIGQTITKTAKYLTPETITSFNNSDVGSLIGQTVTETAKYLTPETIASLNNSDVGSLIGQTVTETAKYLTPETIASLNNSDVGSLIGQAITETPKYLTPETIAILNNSDVASLIGQIITGINTDSNDDNKNENNLDFWKLLEGMQKQMDQYKKFLGIA
>NZ_CP046703|6496978:6567177|6538005_6539388_-|WP_114085537.1|DBSCAN-SWA
MITTELSKIGDIIQNQREFFETGKTKDVTFRIEQLKNLKQAIIEHEQAIVEALKADLHKPELEIYITEIGVIKEIDYAIKHINTWTKPKKAPVSFDFFSYSAKIYPEPLGVVLIIGPWNYPFQLIISPLVGAIAAGNCAIIKPSEIASYTSDVIAKIITKHFDPAYIAVVEGDVEASQKLLAEKFDHIFFTGGTAIGKIIMAAAAKYLTPVTLELGGKSPCIVDTDINLEHTVRRITWGKFINAGQTCIAPDYLLVNKKIKKDLIDGLKKCLKEFYGDNPVSSPDYARIISQKHFDRLVSFLKDGEVIIGGENQSSERYIAPTVIDNVSSEDSVMQEEIFGPILPIIEYTDVAEAIALINSKPKPLALYLFSQNKNLQKRVLQETSSGGVCINDTVMQVGVSSLPFGGVGDSGIGNYHGKASFDTFSHNKSVLQNSFWLDLKWRYAPYEGKLPLIKKLLG
>NZ_CP046703|6496978:6567177|6546546_6547768_+|WP_159402613.1|transposase|DBSCAN-SWA
MQLTDSLKKLLKETAHQLKGAAKRRFIAQTVVALGHGGKSIAERELGWNRVTIGKGIKELNSGITCVDNYQGRGRKKAEEHLPTLLEDIKKLVDSQSQIDPTFKSQRLYTRLGASVVRHQLIEKFGYAEEELPTSETIRVKLNDLGYRLKRVAKIQPQKKFPETDAIFEQLAIVHQEASDDPTILRLSLDAKARVNIGSFDRGGRNRVPTETDDHDFKPKTTVAPYGIFLPDLDELFLYFTESKVTSDFIVDILGDFWKSESWRFSEIKTLLINQDNGGENSSRRTQFMKRIVEFAQSYKLNIRLAYYPPYHSKYNPIERTWAVLENHWNGSILDDVETALNFAKTMTWNGKSPVVKLVTQTYSSGVRLTKKAMQEIENKIERLTNFTEDNLPNLGKWFIDICCGVT
>NZ_CP046703|6496978:6567177|6498787_6499252_-|WP_114084575.1|DBSCAN-SWA
MDFIKKLISGILGFVTGILGFVTGLLPGKKQSNGYFLELDEATSQSKPAASNGKKATAPAASPAAKSPEPQTAKATTTATKTKVEASQNGKAVKAEPAKAAATASQKTPAETTFAPKYLAPSTTSSNGRRRPGANMSAYLDMARQVKTPNTSNN
>NZ_CP046703|6496978:6567177|6542650_6543112_-|WP_114085534.1|DBSCAN-SWA
MIQSSHQIPKATKSLVEYNALSNCVESFGLAKIQRHIFICADQTIANCCSKRASLEFWEYLKERLKELKLDESQQNYSLCVYRTKANCLRVCCSRPIMVVYLDGVWYRQANLEVIERIIQEHLIGNKVVKEYAFFNHPLPETSLVSCEHLIEA
>NZ_CP046703|6496978:6567177|6510017_6511535_+|WP_114085557.1|DBSCAN-SWA
MSVGSDIISISDIAPSAVISESVSLYLSSTITPGSYYLLYQADGFGSLRESNENNNVVAKAITITAPDLVIVDTSVPTSAAIGTTLEFTYKIKNQGNGNAGSSKTAYSLSRDTILGNDDDISIGYDTVPIPSLAPSAIFSKSISWTIDTTIAAGKYYLMFKADGLGDVAESNESNNSVYHTQAISLTPINGGGFNSTTGYGLINAAAAVAKALGQSTFADVPDLGGDNWGADLVKAPEVWAKGYTGQGVIVAVIDSGVDYNHSDLSANIWKNTKEIAGNGKDDDGNGYIDDVNGWNFVSNNNNPLDDNGHGTHVAGTIAGVKNNFGVTGIAYNAKIMPVKGMNSDGQGTNSAIANGIRYAVNNGANVINLSLGGSASSEIQSAIQYAASKGAITVMAAGNDGKSEPDYPARYATQWGLAVGAVSYNGVLADFSNRAGTTPLAYVTAPGVDIYSTLPGNNYDFKDGTSMATPNVAGVIALMLSAKKGLTDAQVRQIVTTTAANSLA
>NZ_CP046703|6496978:6567177|6564144_6564399_-|WP_147262570.1|DBSCAN-SWA
MSISPKIRTQQTPRKLSQEELNVLSSIVSDNNDATLDELRLLLEQKTGVLIGRSTLDRMLRLLNLNLKKKHYTQPRKRVTEFNH
>NZ_CP046703|6496978:6567177|6519759_6520500_-|WP_114085549.1|DBSCAN-SWA
MAEQAIITTTVNLLQDNIQVSAYLAEPKEPGSYPGIVVLQEIFGVNVHIRDVTERIAKLGYVAIAPALFQRTAPGFETGYTPEDIETGRGYAMQTQASELLSDIQLAIDYLKNLPQVKKDSFGCIGFCFGGHVAYLAATLPDIKATASFYGAGITTRTPGGGAPTVTRTREIPGTLYAFFGKEDASIPPEQVDEIEAELEKYKIPHRVFRYDGADHGFFCDLRASYNPKAAADAWEQAKQLFSQLN
>NZ_CP046703|6496978:6567177|6553535_6554600_-|WP_114085165.1|DBSCAN-SWA
MIEQVAIAFDHKDYQTAAKLLKQLLIESPDNPWVQFYLGRLHEVSTKYQDAEKVYRQLLQDTTNTKIVSLARQGLQRLQEIEIEQRQRAISQAKSEPNNTELGVLVLEPLSNEMKTDASRKFAQIMQLDPYTARLLMPSRGWRLYRTGQVGELKFYGKQLQQAGIPCFWASLAQIQQIQVYQVKHFQESTPQATVVCCNDTNQLGSLTFDWSEVTARVVGLLPIFEQVVDVDARRKLEWKTQTQDYAQFCDLHLPGRRCILRFYDNGYEFQQGLKIIPQASQNTIRINWNSLSSWIDQQLPQVKIWSDFTSFADTTLDQTEMLGHIKSHIHLFRREQTNWDSAFHLYSGLVFLK
>NZ_CP046703|6496978:6567177|6550418_6550724_-|WP_114081111.1|DBSCAN-SWA
MIPGEIITPAGEIELNVGRPTIKLQVSNTGDRPIQVGSHYHFYEVNAALNFDREQARGMRLDIPAGTAVRFEPGDEKEIILVSLVGTRQVYGFNAKINGSL
>NZ_CP046703|6496978:6567177|6517056_6517245_+|WP_114085552.1|DBSCAN-SWA
MPNPKGHSENLKPFKSEREEPLSERLNLRVTKTMKEELSTKDDPPEFCRRAIQEALDKDREK
>NZ_CP046703|6496978:6567177|6559513_6560455_+|WP_114085160.1|DBSCAN-SWA
MLTGAKTLSGLMGLCVGDALGVPVEFTSRAERVKSPVTTMQGYGTWNQPPGTWSDDSSLSFCLAECLCRGYSLDAIANSFWRWYKEAYWTPRGDVFDIGQTTHTAIMRLKQGVVPHQAGGKVENSNGNGSLMRILPMAYCHQNLTLGELLARVHDVSAITHAHARSQMSCGIYISIAVALLEGADPQTAYLQALQDIQTIYSVREFLLEKPHFGRIFSGEIAKLPVEEINSGGYVIDTLESSLWCLLNSSSYSEAVLKAVNLGGDADTTAAVTGGLAGIYYGVENIPQKWMNQIARRQDIIYLAERFARAVYS
>NZ_CP046703|6496978:6567177|6551087_6551927_-|WP_114081109.1|DBSCAN-SWA
MTCNSQIAEGWHGKLNLVYADRQDATQLIYNHQQAPLKVQRPFYPEGEKVCHSVILHTAGGMVGGDRLSSNIHLQPQAQALITTAAASKIYRSNGLQARQTIQMQVDAGACLEWLPQETILFNDAIYRQDLRVELATGASWLGWEITRFGRSARGEKFYLGEWRSHTEIWQQGVPLWIDRQWLRGSEDIFHSPHGLAGKPIVGSLVWVGGEVSGEIVEKTRSLWNGEGEAGVSRLQHGLLCRYRGYSTSEVRNWFIDVWQMLRVSFLNRGNCIPRVWQV
>NZ_CP046703|6496978:6567177|6565169_6565352_-|WP_012407712.1|DBSCAN-SWA
MSIEDRAKAFAKNVEGKVQEAVGEVTGNPNDKAEGKAKQAEAQVRHTAENIKDEVKKTLE
>NZ_CP046703|6496978:6567177|6508662_6509973_+|WP_159402591.1|transposase|DBSCAN-SWA
MVQPRPAAPTVKFVDEYCQWYKSLFPDVRSFEAFKYLHVGCISELKRKTLPEIAKIVGLDNQQGLHHFLTTSPWDIEKLRDLRLELILQVLKGRPIILIIDETGDKKKGNKTDYVKRQYIGNLGKVENGIVAVTAYGVFCGMTFPLLFEIYKPRERLKPEDKYLTKPQIAAILMRKLKSMGFKFNLVLADSLYGESGTNFISVLDEMNLNYIVAIRSNHDVDLLPRQYTQYLKWHKFKRVFSDLSSENRFIREIIHGKRSENRYWQITTDREKLPGNTTWYVMSKYPDLTPRDVGNFYGLRTWVEYGLKQSKNELGWSDYRLTHYPDIERWWEIVCSSYLMVSLHSEQIQSSVPKSPSKLASHPWWNDEKGWKNILNNLRLIIQPFTLFNLIYPWLTVFPIPQLSLGFSKLQSIIYSLTSSIFISLTHPDFYFSSA
>NZ_CP046703|6496978:6567177|6556399_6558316_-|WP_114085162.1|DBSCAN-SWA
MVKSAPSPIASRKPSKVEGIKENSNFLREPVATEILQDTTHFTENAVQLLKFHGSYQQDNRDNRTKGQEKDYQFMLRTKNPGGLVPPQLYLALDKIADEYGNHTLRATTRQGFQLHGILKKNLKSAIATIVKNLGSTLGACGDINRNVMAPPAPFKNRPEYQYAWEYAQNIADLLSAQTGAYYEIWLDGEKAISAEEDPEVKAARQSNGNGTIIHDNEEPIYGTHYMPRKFKICVTVPGDNSVDLYSQDLTLVVITNNKKQLEGFNIFAGGGLGRTHGKEETFARLADPIGYVAKDDVYDIVKAIVATQRDYGDRTDRRHARLKYLINDWGLDKFRAQVEEYFGKSIEAFKPLPEFKFHDFLGWNEQGDGKLFLGISIENGRVKDEGSFQLKTALREIVEQFNLPIRLTSNQNVIFYDIEPDSKEAIQDILSRHGVGDEPSKIEPLVRYAMACPALPTCGLAITESERAIPGILEQIRALLDKLGLQKEHFVVRMTGCPNGCARPYLAELAFVGSAPESYQLWLGGSPNQTRLAQPYTEKLHHNDLESFLEPIFVYFKKSRKSKESFGDFCDRVGFDAIREFAASYDPQTANGANKSRHRVNLKEEVYGKLKEVAESQGKPMTQLVTEALEVYFQNLS
>NZ_CP046703|6496978:6567177|6515502_6516378_-|WP_114085554.1|DBSCAN-SWA
MFLVTGATGGIGRRVVRLLRQREQSVRAFVRLTSRYSELEHRGAEIFIGDLLREKDIQKATQGVKYIISAHGSDSDALSLDYRANIELIDQAKANGIEHFVFISVLGADRGYEDAPVFKAKRAVERYLSASGLNYTILRPSGLASNLLPLVERFRETGLYLLIGDRKNRSSIVSTDDLARIVVDSVTVEGARNQILPVGGPEILLREDIPRIFGRIFAKEPVIINSPLFFIDGLQGALGLFNPQVQKALGTYRTLLANEFFCTKDEIANLEAIFNFKLETLENFLRRYLAV
>NZ_CP046703|6496978:6567177|6563869_6564115_-|WP_114085156.1|DBSCAN-SWA
MLAKNLIFIDESGINLSLVRLFARAPKGKQARGERPIKRGKNVSLIGAIGFRGIITQISLIGATDGLTFEAFISQKLVPKL
>NZ_CP046703|6496978:6567177|6521829_6523071_+|WP_114085558.1|DBSCAN-SWA
MQNTFENNQYRRAKVVQIVIVGAGPTGVTLALLLTQRGIAVTLIEAAKDFHRVFRGEGLMPSGLDALEQMGLSPLLEHIPHRQLDAWEFIVGDKQLFRVEEPMGATRPCTLVSQPPLLKALISEAQTNDGFEFIQGVPVKDLRWSNQRVAGVVLSDGRELTADLVIGADGRNSLVRQRIGLELVRQPKNIDILWFKLAASPEFAADNVFRTIVNGDRVFTIFHGAESGKLHLAWVMSATENTDFKQANWAETFASLSPSWLAEHFRNHADTIESPIRLSVVVGYCPQWHAPGVLLLGDAAHPMSPVRAQGINLALRDVIVAANHLVPLLHKEAEHKDIDMALSHIQAEREPEIIRAQQLQLQEAKQGELLRKNALLRSLLSQLAPLLRKIIKKSWLKRQYKMRQGITQVHLTV
>NZ_CP046703|6496978:6567177|6526476_6527913_-|WP_114085545.1|DBSCAN-SWA
MKVTQEKLPASQIGLEIEITPEITKQTYEQVIKNLASTANIPGFRKGKVPRPILLQRLGTTRIKAAALEELIQDGIEQAVKQEAIPAIGQPQLRSSFEDLINNYEPGKPLTISAAVDVEPEVNLVQYTDLLFQAEEVKYDPERVDSTLEKERQELATLIPVEGRSAQIGDIAVVDFKGSFAKAEGEDETAELEPIPGAEATDFQVELQEDKFIPGFISGIVGMNPEETREIAAQFPDPYANEDLAGKAATFTVTLKELKEKELPEINDDFAQEISDFETLEELRASLVERYQKEADDKTKTNKQEALLTELLKHVEVDLPLTLVEQEVDAMLTQTAMRLSQQGLDVRKLFTQDIIPQLRERSRTEAIERIKRSLSLREVGKRESIEVTPEEIAARVKELLEQYPEEKEVDEDRLRSIVENELLTEKTIDWLLEHSSVELVPEGSLSPSEETEGAESDADVSQTEEENSEPSTTEVTEG
>NZ_CP046703|6496978:6567177|6533651_6534029_+|WP_114085541.1|DBSCAN-SWA
MKVFDNTTKKIFLASWVSINQAETTDHKVSQLNHSPSKPYWDILQPLRQRVENIQVRDRQLAHRLCKLIPSQCPFERDVKVFGKTLFHIPPMCKLNPLYEEVVGLRFRALCYLADECGEDVSQYC
>NZ_CP046703|6496978:6567177|6552531_6553440_-|WP_159402448.1|transposase|DBSCAN-SWA
MTSPLARIESYPHEAKRLIGISYDHFLALVGLAEQRHIEKQAEIEKKKIRIIAPGGGRKPEMSAKEGICLCLVYLRQKPIFEILGLLFNISKTKANDAFNYWVDILRDILPASQIEEVSTDSQKYQELQRMLSEYELIVDSTEQPTARPVDYQEQKRYYSGKKKMHTLKNQFIVLPGGEDIVDVRVGMLGKTSDINLFRETRHKFTDTQQFLGDKAYIGDDAITTPHKKRKNTEISELQKQENKELSSRRIAVEHMICRVKIFRVASDRFRLARHRYNQVILAVCGLVRLRINRLFSVTLST
>NZ_CP046703|6496978:6567177|6518748_6519651_-|WP_114085550.1|DBSCAN-SWA
MNSESKLSQTANSSFTMDDFAKALEKHDYQFQKGQVVHGKVFQLDHDGAYVDIGGKSSAFLPRDEASLRAVTDLSEVLPLQEEMQFLIIRDQDAEGQVTLSRKQLEIQHIWERLAEMQENAQTVQVKVMGVNKGGVTVDILSLRGFIPRSHLAERDNLDALKGQNLTVGFLEINKNTNKLILSQRLATRSSNFSLLELGQLVEGKVTGIKPFGVFVDLNGMGALLHIKQVSQKFIDSLEKVFKVGQPIKAVIIDLDEGKGRVALSTRVLENFPGEVLENMDEVMASAEARANRANNKAAE
>NZ_CP046703|6496978:6567177|6541643_6542321_-|WP_012407592.1|DBSCAN-SWA
MDRSATSATAMKEPSMKDHKRLLLIDDDPNLILLVKDYLEFRGYEVITAENGREALEILEQDVPDMIICDVMMPEMDGYTFVEQVRQNERTSWIPVLFLSAKGQSADRVKGLNKGADVYMVKPFEPEELVAQVESSLKQTIRWKEHQAKGGENGSRIQVPFDVQLTPTELKVVQFVARGLANREIAEELNVSQRTVESHVSNMLGKTNLHNRTELARWAIENQMA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_114084573.1|6496978_6498370_+|tRNA	asparagine--tRNA ligase	A0A2P1EJK5	Megavirus	1.4e-87	38.8
WP_114084574.1|6498495_6498756_+	hypothetical protein	NA	NA	NA	NA
WP_114084575.1|6498787_6499252_-	hypothetical protein	NA	NA	NA	NA
WP_114084576.1|6499652_6500285_+	triacylglycerol lipase	NA	NA	NA	NA
WP_114084577.1|6500336_6500768_-	glyoxalase	NA	NA	NA	NA
WP_114084578.1|6501509_6502307_+	TIGR00297 family protein	NA	NA	NA	NA
WP_114084579.1|6502721_6503504_+	peptidylprolyl isomerase	NA	NA	NA	NA
WP_114084580.1|6503452_6506152_+	type I secretion system permease/ATPase	A0A1V0SJ29	Klosneuvirus	1.2e-16	21.9
WP_159402591.1|6508662_6509973_+|transposase	IS701 family transposase	NA	NA	NA	NA
WP_114085557.1|6510017_6511535_+	S8 family serine peptidase	A0A217EQY2	Bacillus_phage	4.4e-42	41.5
WP_114085556.1|6511832_6513719_+	S8 family serine peptidase	A0A217EQY2	Bacillus_phage	5.9e-44	43.1
WP_114085555.1|6513901_6515383_-	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_114085554.1|6515502_6516378_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_114085553.1|6516550_6516928_-	hypothetical protein	NA	NA	NA	NA
WP_114085552.1|6517056_6517245_+	hypothetical protein	NA	NA	NA	NA
WP_114085551.1|6517667_6518594_+	TIR domain-containing protein	NA	NA	NA	NA
WP_114085550.1|6518748_6519651_-	30S ribosomal protein S1	NA	NA	NA	NA
WP_114085549.1|6519759_6520500_-	dienelactone hydrolase family protein	NA	NA	NA	NA
WP_114085559.1|6520766_6521750_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_114085558.1|6521829_6523071_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_114085548.1|6523085_6524006_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_114085547.1|6524117_6525458_-|protease	ATP-dependent protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.4e-135	55.6
WP_114085546.1|6525467_6526166_-	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	2.6e-53	53.8
WP_114085545.1|6526476_6527913_-	trigger factor	NA	NA	NA	NA
WP_114085544.1|6528798_6529836_+	aspartate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_114085543.1|6529962_6530847_+	4-hydroxy-tetrahydrodipicolinate synthase	NA	NA	NA	NA
WP_114085542.1|6531127_6532897_+	ribonuclease J	NA	NA	NA	NA
WP_114085541.1|6533651_6534029_+	nitrogenase	NA	NA	NA	NA
WP_114085540.1|6534159_6536040_-	peptidase C14	NA	NA	NA	NA
WP_114085539.1|6536240_6536723_+	hypothetical protein	NA	NA	NA	NA
WP_012407602.1|6536875_6537049_+	50S ribosomal protein L32	NA	NA	NA	NA
WP_114085538.1|6537324_6537930_+	sulfite oxidase-like oxidoreductase	NA	NA	NA	NA
WP_114085537.1|6538005_6539388_-	aldehyde dehydrogenase	NA	NA	NA	NA
WP_114085536.1|6539582_6540722_-	hybrid sensor histidine kinase/response regulator	W8CYM9	Bacillus_phage	3.8e-14	38.8
WP_114085535.1|6541257_6541566_+	NIL domain-containing protein	NA	NA	NA	NA
WP_012407592.1|6541643_6542321_-	response regulator transcription factor	W8CYM9	Bacillus_phage	1.1e-19	42.0
WP_114085534.1|6542650_6543112_-	ferredoxin	NA	NA	NA	NA
WP_012407590.1|6543477_6543789_+	co-chaperone GroES	A0A221S386	uncultured_virus	2.2e-17	48.9
WP_012407589.1|6543890_6545525_+	chaperonin GroEL	A0A240F779	uncultured_virus	9.3e-155	54.6
WP_159402613.1|6546546_6547768_+|transposase	ISAzo13 family transposase	NA	NA	NA	NA
WP_114081113.1|6548148_6549864_-	urease subunit alpha	NA	NA	NA	NA
WP_114081112.1|6549873_6550416_-	DUF1349 domain-containing protein	NA	NA	NA	NA
WP_114081111.1|6550418_6550724_-	urease subunit beta	NA	NA	NA	NA
WP_114081110.1|6550745_6551048_-	urease subunit gamma	NA	NA	NA	NA
WP_114081109.1|6551087_6551927_-	urease accessory protein UreD	NA	NA	NA	NA
WP_159402448.1|6552531_6553440_-|transposase	transposase	NA	NA	NA	NA
WP_114085165.1|6553535_6554600_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_114085164.1|6554668_6555418_-	16S rRNA (uracil(1498)-N(3))-methyltransferase	NA	NA	NA	NA
WP_114085163.1|6555431_6556076_-	Uma2 family endonuclease	NA	NA	NA	NA
WP_114085162.1|6556399_6558316_-	sulfite reductase, ferredoxin dependent	NA	NA	NA	NA
WP_114085161.1|6558580_6559120_-	porin family protein	NA	NA	NA	NA
WP_114085160.1|6559513_6560455_+	ADP-ribosylglycohydrolase family protein	A0A1S6UB21	Serratia_phage	8.3e-39	35.3
WP_147262571.1|6560526_6561525_-|transposase	transposase	NA	NA	NA	NA
WP_012407575.1|6561546_6562398_-	hypothetical protein	NA	NA	NA	NA
WP_114085157.1|6562536_6563196_-	hypothetical protein	NA	NA	NA	NA
WP_114085156.1|6563869_6564115_-	hypothetical protein	NA	NA	NA	NA
WP_147262570.1|6564144_6564399_-	hypothetical protein	NA	NA	NA	NA
WP_012407712.1|6565169_6565352_-	CsbD family protein	NA	NA	NA	NA
WP_114085155.1|6566283_6567177_+|transposase	IS982 family transposase	NA	NA	NA	NA

Sequences of DBSCAN-SWA_7

Nucleotide sequences of DBSCAN-SWA_7

>NZ_CP046703|6595657:6628147|DBSCAN-SWA
ATTACGTTACTCCACAACAGATATCAATAAACCACTTACCTAAATTTGGTAAATTATCTTCGGTAAAATTAGTCAAACGTTCAATCTTATTTTCAATTTCTTGCATAGCTTTTTTAGTTAGACGGACTCCGCTAGAGTAAGTCTGAGTAACTAACTTAACAACTGGACTTTTACCATTCCACGTCATAGTCTTAGCAAAATTTAATGCAGTTTCCACATCGTCTAAAATACTGCCATTCCAATGATTCTCCAAAACAGCCCAAGTTCTTTCAATTGGATTATATTTACTGTGATAGGGAGGGTAATAAGCTAAACGTATATTTAATTTGTATGATTGAGCAAATTCAACTATACGTTTCATAAACTGAGTACGTCGAGAACTATTTTCTCCTCCATTATCTTGATTAATAAGTAAAGTTTTTATTTCCGAAAATCGCCAGCTTTCTGATTTCCAAAAATCCCCTAAAATGTCAACGATAAAATCGCTAGTTACTTTGGATTCTGTAAAATACAAAAATAGCTCGTCAAGGTCTGGAAGAAAGATACCATAAGGAGCTACAGTTGTTTTTGGTTTGAAGTCGTGGTCATCAGTTTCTGTTGGTACTCGATTTCTACCACCACGATCAAAGGAGCCGATATTTACGCGAGCTTTCGCATCCAAGCTTAAACGTAAAATAGTTGGGTCATCTGAAGCTTCTTGGTGAACTATAGCTAATTGCTCAAAGATTGCATCAGTTTCGGGAATTTTTTTTGAGGTTGAATTTTGGCAACCCTCTTGAGGCGATACCCTAAATCATTTAACTTGACACGAATTGTTTCTGAAGTTGGTAATTCTTCTTCAGCATAACCAAATTTTTCAATTAATTGATGTCTTACAACAGATGCGCCCAGTCGGGTATAGAGTCTTTGACTTTTAAAAGTCGGGTCTATTTGACTTTGAGAATCGACTAGTTTTTTGATATCTTCTAAAAGAGTTGGTAGGTGTTCTTCTGCTTTTTTTCTTCCTCTACCTTGATAATTATCCACACAAGTGATACCACTATTTAATTCTTTAATTCCTTTACCAATAGTTACACGGTTCCATCCTAACTCTCGCTCTGCTATAGACTTTCCTCCGTGTCCTAATGCCACAACTGTTTGTGCAATGAACCTACGTTTAGCTGCTCCCTTTAATTGATGTGCGGTTTCCTTCAATAACTTTTTCAATGAATCTGTTAATTGTATTGACACCTCAAACATCCCAAAATCGAATCATCATTCAATTTACTACAACTTGGGGTGGGAGAGGCTGCCAACGGCAGCCTCTCCCACCCCCCTAACAATGATTATCATTTTTATTATCTGTATATTTTATTTTCTGGAAGTCCCTAAGCAGCAGGTTCAGTTCATCTAAACACTAATTTAAAATGTGCGATCGCTACTTGGCCCATGTCTTGCTTAAGGAAAAATTACAAGCCAAGCTTGAGGAGATTCAAGCTAAGAGCGATGGCTCTCCTGTTACCGATTTGAAGCTAGACAAAACCTTAGCCGAAGAAATTGAAAAATTGACGACGGAACTAGAGAGCGTCAATCCGAATCTTAATCCTCTGAGCAACGCGACTCATTTGTTAAACGGAGCTTGGCAACTGCAATACTCCACTGCTAGAGAAATCCGGTCTTTAGCTTCTCTCCCATTGGGCTTAAAACTGGGTAAAGTTTATCAAGTAATTGATGTTACAAATAAATTGTTTTTCAATCTAGCTAAGGTTAAACATCCTCTGGGGATAGTCTCAGGATATGTTAAAGTGACAGCTAGCTTTGGGCCAGCCAAAGAAGATTTAGAACCTCTAGCTAACAAACGCCTCAACGTTTATTTTGACAAACGCTACCTATCGATTGAGCAAATTGTTGGTATTAATACTCCTCAACTAAACCCATTTAAGGTTGTCTCAGCTAATAATCCTACTAGCAGAGTTGCGACATTAGACATTACTTATTTAGATGAAACCTTAAGAATTGGCCGTGGAGGAGATGGAAGTTTATTCATTCTTAGTAAATCTGATGATTTACCTGACTTCACCTCCTCAATTTAAAATTGATCGCGCCGATGAGTGGATATGGCTCTCTCAATAACGCATCTTTTCACCAAAGTAAAACCAGGTTCTGCAATGGTAGAACTTAAAACATTAAACTTAAAGTTAGGTCATGGTATAGAAGAAGATATTAATGCCGAGCTGATAAGTCCCAGGCAAGTTTTAATTGTTAGGTATGAAGATATTTTAGACTTATCAATTCAACCAGGAGAATTGCGAGAAAATATTGTGGTTACAGGTATAGGATTTGATAAATTTATTCCTGGATCTCTGCTAACCTTTGAAAGTGGTGCGGCAATTCGTCTAACTTTTTACTGCGAACCGTGTAAGCGAATAGCCCACTTAGTAGAATCATTCAAGAGCATCAAGGGTAAAAGAGGAATCTTAGGCGTAGTTACTCAATCAGGTCAAATTCAAGTTGGTAGTAAATTTCAGGTTCAAGCTCAGAAATTTCCAGCATTACCTGAAAATCCTTATGAACGATTTCTAGATTTTATCATCAAAATTCCTAGTGGGAAAGTAGTTACATATAAACAGATAATTAAAGCTATAGGAGTTGATAATAGTTATCTAAGAGCTATTCCTACATATCTGAAAAAAACCTCAGCTAATAATTATCCAGTACATAGAATATTAGACTCTAAAGGTTATTTAATAAATTATGTGAACCAACAAAAAGATAAGTTGGAAACTGAAGGAGTTAAGGTTTTAGCAGAGGCAGACGTAGTGAAAAAATTAAATAAAAATTATGTAGATATTAATAATTATTCATGGGAAGATTGCAACATATATTTATAATAGATATTGCTTATTTAATTATCATGGTAATTACAAGATTATCCGGCATTCTGAAAAGTAAAATGGTTCCTTGGATCAAGATAATCCTTGATTTTTGATTTGTTTAGATGTGGCTTCCATAAAGTCAATGAAAACTTTTATTAGCTTATGAATTCCCTCGCTACCTCCTGCAATTAAACCTCCTGTCAGTAACGCATCTAAACAACGAAAAATAATTACTTGAATTGGATTATCGAAATCAAGAACTACAAGTGGCTCAATTGATCGAATACCTATTGCGCTCATTAAAAGCCCAAATAAGAGGGATGTCCATAGAGCAATTACTCGTGTATCAGATTTATAAGCTATCTTTTTGCGCTCTTTTTCATTTAAATTATCCATTTGTGGCTTGAATATTTTTAATGATTCCTGTTGGTTTTGTGTAAAATTCTGGATAATTTGCTGTTCTAAACTCATTCCTTCAGGTGGTAGCCCAATGCTTTGATTTGATTCAAAAGAAGGAAACTGTTTTTGTTGGACTTCTATAAGTCTTAGTTTTTCGGATATAAGAGCCTTTTCTTGTTGAATACTAATATCTAATTGTTCCACGAATGGGCCGCGCCAAGTAGTTATAAAAACTTCTAAAGAACGTTCTAGTAATAAAGAGATAAATAACTGTAATGTGAGTATTTGGATAATATCATTCAACCCAAAAGGTTTTAAAATAAATGGTTTAGATAATAACCAGGTTGACAAAGTTACTATTAAAAAACTAATAATAATTAAGACAAAAAATAGAGGAGATTCTGGAGAAAGCTTTAGCAACGTATCTATACTCCTGTTTCGCGTCACAATATTTAACACAGCCTGGAGGTGGGAACTACACCTGCTGAGTAACTTAACAACGTTAATTTGATAGAACAGTAAATAATTTATTACCCGCCCCTTTTTTCTGGGAGTGTGAGAGGCTGCGCTACAGTGGGAGCAGGGTAATCAGAGGGTTTGTGACATAGCCGAAAGTGTTGCTATACAAGCATTATAGGAATAAATGTACTGTACATGGTGCGATCGCGCTTTTCTCTGGGAGAAATATGAAAAGGTGCATTGAAAAAAGGGGACGACACAAAAAGCAAGCATCAACTAAAAACCCCTCCAAGGTTGGAAGGGTTAAAGTAATTTTTGGTAATGGGATGATGATTAGGGGTAAACAGAAGCTTTCCCTCCTTGATGAGCTAGAAATGCAACATCAAAAGGTATGGGGTCGCTGACGTTTGTAGAATGAGTGGGTAGATTCTTAGAGTTGACAGCTATAGGTTCGCCACTATTGTGAGTAACTATTTGAGCGCCACCCATCCCAGGCAATAAAGCAATCGAAGTAACAATGAGTACAGAATCTATCAAGATAGAAAGTTTCATAAGGTTCTATTTAGTTAAAGTGAAGTGTAATTAGTGTTCTTAGGTAATAGAGTCTTATTTTTTATCTGTCTTAACTTCCTGCATTCAGATTACCCGATCGGTTGATTTATTCCTCACCCATTAGGATGAGCTAATGGAGTGAAAGAGCTGAAAAAGATCATTCAAAGTTACTAAGCTTGGTAAAAAATATTTGGGTATACCTCAATACAGTTCAGTTAAGTATTTCTTTATTCTCTCAGTGCCCTCTGCGTCTCTGTGGTTCGTAAAAATATTGACTTTGACAAAGAATTTTAGCCTTAACTAAACCGTATTAGGGTATACCTCAGTTAGCTAAGAAACGCTACATAACATATTACTAAAGACTTTCGAGAGCTTTGAGAACCTCTGCTGCTGACTGATATCGTTGAGTAAAATCGAAATGCGCCATTCTATTTAAAATAATAACTAACTCGTTTGTAGCCTCAGTTAGTTCGCGCCAATGTTGCCAAGTCTGTTGATTGCCATCAGCACCACCTTGAATAATTATTTCACCAGTATTTACATCTCTGCGATATTCTCTAGGATCTACCCCAGTTAAACCTTGAATTCCCATAATTCCCAACGCATAAATATCGCTGTTGAGTTTTGGCAAACCGCTCATTTGCTCAGAAGGTGCATAACCAGGCGTACCAATTGAAATAGTCTGAGCTTCTTGCTGCTGAGGATGAATTTGCTTAACAGCGCCAAAGTCAATTAAAACAATGTGTTGATCTGATTCTCGTCTAATCAAGTTACTAGGTTTGATATCTCGATGGATTACACCATAGCTGTGAACAAAAACAAGAACATGTAAAACTTCTTTGAGCATTTCCACAACTTCAGCTTGTTTTAGTCGCTTTCCAGAGGTTACTTCTTTGTCCATAGCGTGCCCTCGAACAAATTCTTGCACTAGAGAAAATTGCCGATTTTCTTCAAAAAAAGCTAGCAGTTGAGGGATTTGTGGATGCTTACCCAAGGTTTCTAAAATTTGTGCTTCAGCGTCAAATAATCGTCTGACGACATTTAAATATTCTGCATCTTGGCGGGGGGGACGCAACTGTTTAACCACACACTGCGGATTACCAGGACGCTGGATATCATCAGCCAAATAAGTATTACTAAATCCTCCAGAACCCAAGCCTTGAGTAATTTTGTAGCGGTTGTTTAGTAGAGTTCCTAGTGAAATTTCTTGCCCGATGGAATCAGCAATTACAGTTGGTGCTTCATTTGAGGCATCGCCGCGCTGCCGTAAAAGACCTTGCAATTCCACAATTAATTGTTGGTGTTCTTGAACCCGTTGGGTAATTTCTTGTTGCTCTTGTTTCGTTTTATAAGCACTATAAGCAAGAACACTCCCGGCGGTAAATACTAACCCCAAAGTCGGAGGTATTACCGGGAACCATCCAGCTTGGGTAAAAATGACAAAATTGCCTCCAAATAAGACTGCAAGGGCTGTTGCTCCTGCCAGTCCTAAGCCTAGTGGATGTTGAATCCGCGATACCAGCAACCCACCAACTACAGTCCATCCCCATATCCACAAGACTTTACCCCATTCAGGTAGAAACCAAAATAATGGCTGTTTGTTAAGAACAGCGCTGAGAATTTGACTAACGCTGTGGGCATGAATTTCAATTCCTGCCATTTTGCCGGAATTATCTGACTTACCAGTAGCAAATGGCGTGTTAAAAATATCATTTAAACTATTGGCTGTTGAACCAATTAAAACGATGCGGTCTTTCACCAAATCTGGTTTAACTTGATTTTCAAGTATTTCTGTAATAGTTACTTTCTGGGCAATCTGATGACCAGAATGGTAGTTAAGCAAAATTTGGTAGCCATTTGTATCTGCTTTCTGATAACCGCCAGCGTCGCTTTGTAGGGGTTTAAATACAGTATCTCGTAGTTGTAGTTCTTTTTTTGGAGTAAATTTTAGTTGGATGCCTCCAACTTCTAAGTATTTAAGTGCTAGTTGTAAGCTAAAAGAATAAGTGCTTTGACAGGAATCTGACTCTTCTGCACTTACCAATAATAGGTTGCGACGAATTGTCGCGTCAGTATCTTCTACTACATCATTAAATCCTACTCGCTCTGCTTCAATCCCCTTTGGGGCTGGTATTCCCGGATTGTTAGAACCAGAATGTTTACAGATAGGAATGATGATATCGCTCTGTTGTAGGCGTTGCAGTAGTTTTTCATGACCAGGTTGTACAGGTAAGTCACGGAAAATATCTAGACCAATGGCTCGCGGTTCATAAGCTTCAAGTTTGCCCAATAGTCGGTCTAGAAGTTCGCCAGATAGAGGCCAATTCCATTTTTGAATATCTTTTTCAGTTAAAGCAACAATCAATAGACGAGAGTCTGGGCCTGGGTCGCCACGTAATTGCATCATTTGATCGTAGACCTTCATTTCTAGAGGCTCGAAAACCCCAAGTTTTTGAATGCCTACTAGTAAAATTGTAGCGATCGCACTTGAAAGAATAACTGGTTGTCTAAATAAAGTTTTTAAGTTTGTAAGCATTTCTCTAGATAAGTTTTATTTTAAAATATACATATTTTTTATCCTAATTTTCACCATTGAAATTATTCTATGCAATTTGCAACTTTTCTCGAAATATGCAAATCCCCGACTTCTTTAAGAAATCGGGGATTTTGTTAATCACGAATGATTAAGTAGGGCTATATATGTTTAAGATAATGCACGATCGCTTCTGCTGTTGGCAAATTAGTTGCCAGCAAAACTTGATTAATAGTGCATAATCTGAGCAGTGCTTCTTCATTTGCCTGACCAGGCTGAGGTTGCAGCAAATCTCTCAGGAAAATAACTGCTAAAATTTCTCCCGCTCCAACTAATGAAGCAATTGTTTGATATCCTCCAGAAATCGGTGCTGGGGTTTGCTGACTAATAGTTATTCCTGCTTGTTGATGTAAGACTTCGCCAACAGATGGCCAGGTAATTGTAAAGCTCTGTGAGAAAAATTCCTGATGTTGAGAAACAAATTCAGCAAGTTCTGATTTCTTGCTCTCGTGAGCGATGAGTACTATGTTTCTTTCAATGATCACTTGGGGAGGCTCACTTACATTTATTTCTTCTGGAGTTTCATCAAATTGAGCCGCTTCTACTTCAGGAACCTCTTCAATAGTTTGACTGATACTCTCAGGAACTTCGCTTTCTGTTGTTTCCAAAGATTGAATATCAGCTAATTCAGAAACTTCACTTACTAGAACAACATCATCAACATTTACGCTGGCTTCTTCTGTAGTTGTATTATTCAAATCAATGTATTGATTGCTAGAAACTTCTGCAACGATATTATCAGGCTCCGTCAATGCTTCAGAAACTTCGCCTCCTGTTTCATCAACAGCAAAACTAGGTTCTACTTCGTTAATATTTGTGCTGTCTTCTGTCGTAAATAAAATATCTAAATCTGCTAATTCATCATTGATATCTTGTGTAGGTTGGCTCAATGTTTCTTGCGGCTGAATCTCCTCTTCTTCTGTAACTTCATTGACAAATTCGCCAAACTCTAAACTGACTTCTTCTGCGACTGGTGTATCTAAATCTACTACTTGATTTTCATTATGAGTAACTTCCAGAACGGTACTTTCTTCATCAGACACTTCGCCGAAAATATCACGCGGCTGCACAAAGGTGACTTCTGCTTCCAGCGCCGCCTCTAACTCTGCATCTTCTGGGGAGGTTGTTTCGGGAACTTGGTGGAAAATATCACGTGGCTGTACGAAGGTGACTTCTGCTTCTAGCGCTGCTTCTAACTCTGCATCTTCTGGGGAGGTTGCTTCTATATCACGCCGTTGCACGAAAGTAGATTCTGTTGCCAGTGCTGTTTGAAAGTCTGTAACCTCGTCGTCAGTGGCTTCTGGAAATGTAATTTCCTCTTCAGAAGTTTCGATGATATTTTCAGGTGCTGCGATCGCATCATCAGCTACAGTAAAAGAAACTTCCTCACCATTTTCGCTAACTTCTGGAATCTTTACTTCCTCAACATCTGCACTGACTTCTGGTGCAACTAACGCTTGCAAATCTCCAATCTCATCATGAACATTGTGTGGAACTTCGCTAACTGCTTCTGGTGACTGAATGATGTTTTCAGGGGCGATTATCTCAACAACCGGAATGACATCATCGGGTTGATTAGCAACAACTTCGGAGGTTTCGCTTACTTCTGGAGAAGGTGTTTCTACTTCGGGAGTAATAGGCGCTGAAACTTCGCTAACTAGTTCTGGGGATGGATTAACGACATTGGCTGCGCTGACACTTTCAGGCGATCGCGGCCGAGAAAACAGTGAAGGGTCTATAATTCTAAAGACTGTCTCTGGTTGCTCATAAGCGGGAGCAACTGCTTCTAAGATCAGAACGTAATCTGCAATCCTGATAATATCTCCATCACTCAAAGAATATGGTCGATCTTTTTCGGCTTGTTTTCCATTAAATATTGAGCCATTTCTACTGCCAAGGTCAGAGAAGTAGTAATTTCCAGCTTTAACAAAAAACTTAGCATGTACCCGACTAATATCAGGACTGTCTAAGACTAAATCAGAATCAGGAGAACGACCTATTAACCATTCTCCTCTCGTTGGAGTTTCTGTGGTCAGGTCAACTTCATTGACTTCACTTAGATTTGGTGAGTAGCTAACTTTTACTTTCATATTAATTTTTGGTTAATTTTATTGATTTCTGCTACCCAGCGCTGACGGGTAGTATGTTCTAAATTTAAAATATCATCTTGTGACCAGTGGAAATGATAAGCAATAAAAGCTACCTCCTCATATAAAGTATCGGAGGGGTAGCTTATGACTCCCCCGCTAGTTCTAGCTCCACAGAAAATTGGGTATTACAGTGGGGACATTGTGTCGGAATATGTACATCGCCTTCCTGATTGATTCGATTATAAAATTCTCGGAGATAGGCAATGTCATGTAGAAGAAGTTCTTCAAGTAAATCAGGGCTAACAGAGTTAAGACTGCCCAAGCGAGTAATAACCCGTGCAAGCATCACCAAAACACCGTAAGCTGGATTTTCCTGAACTCTGCGCTCTTGTTGCACCAAAATTTCATCTTTAGCGGTGGCTAAACGCATCACCCCATGACGATGTACCCGGTGTTCATTATCACTCAATCCTCTAGGAAGAGTGAAGGCAAATTCTGTGCAGAGAGTATCTTTCTTACGGCGCATAGGTAATTTAATTTGAGAATTGGGCATTGGGCATTGGGCATTGGGAATTGGGAATTAGAGAATAGGGGATGAGTCTTTGAACTCCATTAATGAGTCTTTGCTCTTTGCTCTTCTGCTCCCCACTCCCTATTTCCAATGCCCTATAACCCATGACCAATTCAATTATGAAGAACTGCTTCGGGAGAATTTACTGTATCTTCCGGTATGGAAGTTTCACCTTCCAAGCCATTAATTCGCCGATAAAAATCTTGGAGATAATTTAAATCTTGGGCAAAAAAGTTTTCTACTATTGCAGGAGTCACTTCTGATAAAGCACCCAAGTGAGTAATCACTCGTGACAAGATAATAATTGTGGCATAAACAGGATTAGCTTTAACGCGTGGGTCGCGCAAGGGTGCAATCTCGTCTATCGCCGTTGATAACCGCATTACACCTTTGCGGTGGAGGTTGCCTTCAGAGTCTAGATACCCCTTTGGCAGTGTAAATTCAAACTCTGTGGGAAACATACTTCTCCTAATTATTTCACGCGTTTAAATTCCTCAAAAGCAACCTCCACCTCCTCAATTTCGATGTCATGGCTGCGGGCGTTAACATCGGCAATTTTGTAACTTGCAGGCCAAGCACCGGCTAATTCAAATCTAGCTATTTCTTGATTTGCCTGATTATAAATAGACAAAGCAACAAGTCTACGTTGCTCAGACCAATTACCCTTTTCGACTTTTTCAAACCACTTCCAAAAATCCATAGAGTTGGTAGTACCTCTACGCAGAGTGAGATTACCACTCTTAGGATTGCTAGGAAGCTTAGTTCTCACCACCTGACCTTTTGATTGCCCTTTTTTACCCCAGGTTTGAGAAGTAACTTCAGAAATTTCAATTACCTCTTGGGTTCTTTTGAAGCCTTGACACTCCAAAAAGAAGCAATTGGCATCGTTTTGACCTTCTAGTGTCAGTTCTAAATAGAACCGATGGGCCGTAAGAACTTCTGGAATTCGGCTTGCGGATTGTACCACTGTTAATTACTGCAAATGCTAATTATTTGATTCGTTTAATTCCTTCGTGAACCAATTCAACTGTTTCATTTGCCATATCACCACCAGAGGCTGTTAAGGTAGGCCCGGTGTATTTACAGGGATAACAATTGACAATGTTCCAGCGTGCTTTTTCTGAGCCTTGTTGGTCATAAGCGACCACTGAACCAGTTTTACGATTCTGTGCCCACTGACGAGGATCACCCATGTCTTCGTTACACTTTTGATACCAAGTATAAAGGTCTATATCATCAGTGGCGATGACTTTTACTGTGATGTTAGTAAATTTAACAACAGTTGGTGTAGCTTGACGCATTAGTTTAGCGCCTTTAGATGAACCGTGAACTTCTTGTGCTGGAGTATTCTCAACGCCTAAGCCACTAATTTCTTTGATGAACTTATCAGTAATTCCATCAGCCTCGAAGTAAAACTTACAAGAGGTTAAAAATTCGCCTGCCATACTTTTAGACTCCTTTGTGTGTGGTTAATTTGGGAATTGGGAATTGGGAATGGGGAATGGGGAATGGGGAATGGGGAATGGGGAATGGGGAGTAGAGAGCAGGGGGAGCAGGGGAAGCAGGGGAAGAAGAACTATTGATTATTGAGCAATGCCCAATGCCCAATGCCCAATGCCCAATGCCCAATGCCCAATGCCCAATGCCCAATGCCCAATGCCCAATGCCCTATTCGTTATCTTCAATGCCATTCCATTGGCTGATGCGGAAAACAACAAATTCAGCCGGTCTGACTGGGCAAACACCGACTTCAATATATAAACGTCCTAAAATTCTGGTTTCTGGTGGGTTCAATTCTTCGTCACACTTCACATAGAATGCTTGTGCTGGAGATGCCCCAAACAAAGCACCTTCACGCCAGATGCGCTCTAAGAAGTTACTGACGGTGCGGGTGACACGTGCCCATAAATCTTGGTCGTTCGGTTCAAAAACTACCCACTGAGTTCCCAGTTCTAGGGATTTTTCGATATAGCTAATTAACCGACGCACACTGATGTAACGCCACTCTGTTTTATCTGGCTCAACTAGAGTGCGTGCGCCCCAAATGCGGATACCTCGGTTGGGGAAGTTGCGAATGCAATTTATCCCCAAGGGGTTTAATAGTTCTTGTTCGCGGAAGTTGGTGTCATAGCCTAAACCAATTACGCCTCTGGGAACTTCATTTGCGGGGGCTTTGTAAACTCCTCTGGTTTCGTCGGTGCGGGCCCAAACACCCATCACATGACCACAAGGAGGTACTAGAATTGGATTACCGCGATCGCGTGGATTGGGTACTTTAATCCAAGGATAATAAAGGGCCGCAAACATCGAACGACGGTTAAATCTATTCAACCACTCAACTACTTGCTGGGGTTTGACGGCATCCGGTGGCGCATCAAGTACAACCATGCGGTTGGGGGGGTTGGGAATATCGCCACTGGCAGAACCCTCACACATACTAATCATCAGTTCGATGATGCCGTGGACTTGATCTAAATTCAGTATCTGCTCTTGATAAGCCCGCATCACATCAGGACAAGCCAGCATTGTGATTTCATCAACTTCAAAGATACCGCGTACCCCGGTGCGATCGTCTCGAACCCCTTCTAAATTTTGTGAAAATCTATCGGGTGGAGCGGCAACAATGGGTGGCGCTAGTTCATATTGACCATTCACGGGACGACGAGCTAAAGGCTGTCCACTTTGAGTAATGTCTTCTACACTGACATACATCGAATTTCTCAATGCCGCTAACGCATAAGTCGCTATCTGAGCAGCTGGCTCGCGGTTCATTGTCAAGTTTTCGTATTGCTCTAAAAGTTCATCTCCCCGACGAATTTGAATGGTGAAATATTCACCTGTATTTGGAGGCGCTTCTCCTTCAGTACCTTCCGGTAAGGCGCGGGGTGAACCATCAATAATTACAAGATTTACTAATCCGCCTGATGCTTGCTCAGGACGTAAAGTAAAGCGCAGGGCTGGACGATTACCTCTAGAGTTGATTCTGAGAGTCGCCGGTTCTGGAGTTGCAGGTCTGGGTGCGCCTGGTAACTGAGTCCCAATGCTTGTTACCCAGCAACGACCGCCACCATTCATAAAGTAGCCGTAGACTGAAAAGGGTAAATAAGCGTTGAAGTCGGTGAAGCCGTCAGAATTGGGACGGGCAAAGTAGTTTAAATATTGCGTCCAAGTAGTTACTAGCATGGGCTTATATAACTCAGCCCCACCACGAACGTCTTCTGTAAAACCTACAAATCCGGCAACTGCTGTGCTAACACCTTCAATTGGTCGGCTACCCCGGTCAATTTCTTCGATGTAGACACCAGGAGCAAAGTAATCAAGTCTAGCCATGAAAGTTTCTCCAAGTCAGTAAAAATCTAATTATTCAGGAGTTAGAAATATTTCTTTGAAAGTATTACTTTGGTTATCTACCAATGCATTGACGTTTTGGGGTAAATAGCCAGGATGATTCAGAGTCAAAACATAATTACCTAAATGAAGGTCTTCAAAGAAGAACAGCCCTTCTTTAGTAGTTGATATGGACTTTTCAGTTCCCCTCACCGCTACTTCTGTCGCTACCAACGGCAGATTTGTCACCGCACTTTTGACAATGCCTGCGATCGCAACTCGCCTGGTTAATACTAGACTGTCACTATCACGAGACAATTGATTTCGTAAATTGAAAATTCGCTCCCAAACCAAAGGTACTGGCGTAGGTTGTGGCTCGAAGGGAATTGTAACTGTCAAATATAAGGCTGAACGCAATGGCACATTGAGAGCGCTCCATAAAGAGCCAATTTCAATTGGCGGCTCTAGGGCAACTGTCATGTTCAAATTACCATAGCCCCGTAATTCAGGAACCAAAAACTCCTCTTCCAAGGTGCGATGGCGCAACAGCACAGCCAACGCCTCACTGATAAAGTGATGCTCCCCTAAAGCTGTTCTATCCCAGGCTGTTAATAGCAGTGAAACATCAAACCAAGCGGGTGCCCAATTTACAGTGGCAGGTTGTAGAGCGCGTGTTAGCTTGCGTTCAACTTGCCTACCAGAATGTTGTACCTGCTTACTCTCACGTATATCAAAAATGTATAAATTGAGAGTCGGGCCTGCTCCCTCTTCCCTTCGATTACCAGGATGGCTAAAGTCAATTTGCTCTGTACTGGTAAGTGAGGTTCCTCCAGCTAGAATTTCGGCTAAAGTTTGAAGAACGAAGATAAGCATGAAGGTGTTCTGCTGGTAGCTAATCCAGATGCATCTACAGTATATGTATCAGCCTTCTAAAGGTAATTAGACTTTTGTCGATATTTTTAGATTGGGGATTGGGAATTGGGAATTGGGGATTGGGCAAAACAGTTCCGTTAGCGGATAGCTCAGGTTTAGCCCGTGAAGAGTTAGGAGTTACGAATTCTCCCCCTGCTCCGAATGGCACGCTTGTTAATCGCAAAGCCCTGATATAACTTGCTTTTTGAGTGTGGGGAGTGTGGGGGGTAAGACTTCTTCCCCATCCTCCCACACCTCCCACACCCTGCCGGCAAGGAGGTTCCAGCTTTTCTTGGTGCCATTCTCCCTTGCTCCCCTGCTCCCCATTTGAGTTGGGCTGGAAGATATTAGATTTTCGAAAATCCGAAAAGCAGTAACTTCAGTTTGTAGATTAGTCTGGAGCAGTTCTTAATAGGAGTGGCGAGATGACCACACCACAAAATCTATGCGTTGTAATAAAAAAATGCTCTACGTACCTATATATACTTAGAAAAATGATAAATATATATAAACGTAAACTTAATAATTCTTTGTATTGATTATCTAAGAAGATAACTTAATAAAAAAATAAACATTACTGAGACTGCATAAATTTATACTGGTCAGCAGAAGAATAAAAACATTTGGTTGCAAAAAGCGAGTGAAGCTATGACACTAGGCTTTTATGTACAAAAACTGGAGAATGGCTCGAATTATTTGAATTCCTCAGATATTCAGAGCTATTGTCAATTAGAGTCTGAACAGTTAACTAGTCAATATCCAATTTTTTTCGCTCGGATTGTATATCATGATTACTTGCTGAAAAATCATCAGGAAGTTATAAATTATGGTCAAGACCAAGCTCCTTTTTCCCATAAAACTTTAGCTTATTTGCGCTCTGAAGCATGGCTTACAGATTTTCCGCCTGCTTTGACTTTGCATGAATTTAAACTTAAGGATTTTTCATCCATTTCTTACATTTGCCCTATAGGATATAAAAATCAAAAACCTGAATACATTCAAATCATTACTCATAAACCTCTGTCAGAGAGCTTGCAATTATATGTAAAACGCTCTGCTATGCTGCTGAGTAAGTATGCAGATATTTACTTGGACTATGGAAGACAAAAAACTGAAATTCAACTCCTGGAAGATATCTTGCATCGAATAGGCCATCAATTGCGTAACGCTCTAGGGCTTATAGGATTGTATGCACATAACTTATGCTTAGGTTTAGAGGATAGTCCTTGGCAAGAGCAAGCAACAATCATCGGCGAAAGTATACAAGATTTAGATACTAATTTAAATGAGCTTATTGATTGTGGGCAAAGTGCAAAATTGAGAGTAAAACTTCAAGATTTAAGAAGTTTAGTTTATGAAAGTATCAAAAACTTACAGCCTCTAATTAATCAGAAAAAACTTAAAATATTGATTCCAGATACATCGACAATACTGAAGATAGACAAATTACAAATGAAACAAGTATTTGATAATATCCTCAGTAATGCCGTCCATTTCAGTCCTAACTCAGGAACTATTACCTGTAGCTGGCAAGTTTTTCAAGATGAAGTTTTAATTAAAATTTCAGATCAAGGGCCAGGATTATCACAAGAGGATTTACAAAAAGTATTTACCCCATTTTATTCCCGGCGCAAAGGAGGTACAGGACTAGGCTTAACTATTGCGAAGAAAATTATTTTGGATCATCAAGGAAGTATCTGGGCACAAGCCTTATCAGAAAATGGAGCGCAATTTTCTGTAATTTTGCCTCGACCAAGGAGTATGAATTAATTCGTAATTTGTAATTAAAAAAGATGGCTAATGATAGTAAGAAACTTTCGGTTTTGCTGGTAGATGATGAAGAACGCTTCCGCCAAGGATTACGTACTCTCCTGAATTTTTATAGTATTAATTCTGCATTACCTGTAGAAGTTATAGGTGATGCAGATTCTGTGGAGCAGGTTTTAAAGTTTACAGCCCAGAAGTGTCCAGATTTAATTTTGCTGGATATGCAATTGAAGGGATGTGATGGGATTACAGTTCTGGCACGTCTTAAGGAAACTGCTTACACTGGAAAAGTTTTAGTGTTGTCGGCTCATCAAGAAGACGACTGGATTTTTAGAGCAATGCAGGCCGGAGCCGCAGGTTATGTGTTTAAAAATCGTGTGGCAACACAATTGTGTGAGGCTATTGACACTGTTACAAGAGCGGAAATTTATTTACCTTCAGAAGTTGCTAGTCGATTTTTCCGGTTTTTTCAGGCTTATTCAGACTCTTGCCTGAAAGCATGTCATGAGGTGCATTTAACCGAAAGAGAGCAGGAAGTTTTATACTGGTTAACTCAAGGTGCTTCTAATGAAGAAATTGCTAAACATTTATATGTAACAGTTGCTACTGTTAAGGCGCATCTCACCAGTATTTTTGAAAAATTGAAGGTTACTAGTCGGACTCAAGCTATTGTGGCTGCCCTCAAGTTAGGATTAGTTCACGCTTGAGCGCGACGAAAGTAATCGGCGCAATTCACGAAACTTTTTGTATATGCCTTCATTTGAATCTTTTTATCAAGAATACCCCTGCTCGTATAATTCTCCCTTAAGTTGCGATCGCCCTTTCCAAACCGCGCAGCAAATCAAGGGGGCTAAGTTTTGCTTGGAATGTGGTTTTCCAGCAACTTTACCACAGGAGGCTGAGATTAAAGGAAGTCAGGGAACTTATCAAATAGCTAGTTTTATTGGTGTACGGGGTTTAGGCCGCTTATACTCAGGTGTTCAACTTAAAGATAAACAGCCTGTCATTATCAAAGAATACCTACTACCCAATCGTTGTTTTAATGAAAGCGAGACTCTGAAACGCAAAGAGACTTTCAAACGGGTGGGTGGGGTAAGTTTAGCCGATAGTCGAATTCAAAACTTTCGTCTTGTAGAAACTAAAGAAGCGATCGCAGATGAAAAAGGAGAACGCTGCTATCTAATCACTCAAGGAATCGAATCATCCCAAACTTTAGGGAAATATCTCATAGAAAAAGGAGCGATGACATCTATTGATGTGCGGGAAGTATTAAATCAAAGTTTACAAACTCTCCAGTTTCTCCACACCCAAAAGCTGCGTTTTCCCTCAAATCAAGTACAACTGGGTATAACTCACGGCAATATTAGCTTAGATAGTACTTTAATTAAACTAGAAAATAATCAAAAATTCTCTATATACTTTTGTGATTTAGCAACCTGGGAAAACTTATTTATTCCACCTATTATTCCTCAACCCGCGCCTGCCAGACCTGAGCAAGATTTAGAATCATTAGGATTGCTAGCCTTTTATCTATGGACAGGACGGACAACTAATTTTTTATCCAACCAGCCTCTCGACCCTAGAGATAATCAACAATGGCCGGATACCGATAGCCATTTAAAGCAGTTTATTTATCGCCTCATTGGTCTAGAAACTCCTTTCGAGAATGCGGAAACGGCTCGTCAAGCACTGCTGCAACTTCCCAAAGAAGAGCGTGGCAAAAGTTCAGTGTCATCGCCAGCTTCTCAAGCAATAGAAAAACGTTTACCAATGCCTTTAATCCTGATAGGAATTCTGGCTTTATTACTACTCGGCGGAGGAATTTTGTATTGGTTTTTGGGCAAGAAAACAGATAGTCCTAATCAATATATATTATGGTCTAGACTTGTGCGAAATTTCTCCGAAGTTCCCAATGTTCCTGCCGGGCAATTTACTTACACAGGAGAAAAAGACAGTACGTGGAGTTATGTTTTAACGCAATCAGTAGAAAATAGTCGTTTAGGAGAGTTATTGACCAGACCAAAGCCAGATGCGACAGCAACATTTAACTATCAGTCTGTTTTGTCAGCAAACGTCAAGAATCCGATTAAAAGTATCGAAGAAGTTGAAACAAACAAAAAAGATTTTGCAATTACTAGTTTGGTAGACAACATCACAGATAAACTTTCTAAAAAACAAGTTGCTTATGATGGATTAATTGTTTTTGTAGCATTTAATAAGAGAGACTCAAATCTTGCTAATGCTCTTGGAGGGCAAATAAGTCTTGAGCAATTGCGTCAAATTTACACAGGTAAAATTACCAATTGGCAACAAATTAGTCCGAAACTTCCAAATTTAGCTGTGAAACCTTTTGCTCCAACAGAACCGGAAGCAATCAGTAAATTTCAAGAAATAGTTCTCAAAAACGTCCCTCAAGACGAAGCTTTATTTGCAGCAAATGTTACTAAGCTGGATACAACAAAAACCCAAAATCAGATACGCAGCGAGACTCTAGATGGGCGAACCACTGGTATTATCAGTTTTGGCATTATCAGTAAAACTTCGAGTCAGTGTACTGGTTATCCGCTAGCGATCGCAGATGGCAAAAAATCAGCGATTCAACCTCTGTTTCAACGGCGCGATCGCCGCTCAATTAATCCCTCAGATGACTTGTGTCAACATGATGATTATTATGTTGATGTCACAACATTCCAAAGCTACCCCTTGGGATACCCTATTTTTGTAGTGTACCCTAAAGACACCAGTCGCCTGCCTGGTGGTTCTACATTTGCCCAGATGCTAACCACTCGTCAAGGTCAGTGTTTACTTAGTAAAGTAGGTCTCGTAGCTTTACAACCTATGCCTGATGATATAAATTCCTATGCCTGCAAATCGGTGCCCCAATCCTAGTTGCGAATATTTTAACCGCGCCCTGCCTAACAATGCTAAGGTTTGTCCCTGGTGTTCCACTCCTGTGGGTAATGTAGTTTCCTCAACACCACAACAACCGCCTAGTCAACCACCACCTATTCAGCAACAACCTAGTCAACCACCACCTGCTCAGTATCAACGACCGCCTACAGAGCAACCTAATTACCAACCTCCCCAACAACCCCCCGTTGATTATTCAACAGTCTATCAGCCACGAGTTTCTTATCAACCAACACCGCCTGCTTATGTCCCTCCGCCTCAAAGAGCGCCAGCCTTAAAGCTGATTCATACTACTGGCAGAGAATTTCACCTCGTTGGGGAAGGAGGTTATATTGGTCGCCGCAGTCAAAGTCCAGGAATAGCGCCGCCAGAAATTGATTTGACCGGCATTCCCAGTGAGGGAATAGTCTCTCGTCGTCATGCGCGAGTCGATTGGGACTGGTCGCAAAATGCATACATGATTGTTGATATGAGTACAAATGGTATTTATTTAAACAACAATCCTCTCACTCCTGGTATGCAATATCGCCTGCTTAATGGAGATTCATTGCGATTTGGTCAGGACAACCTAGTTAATTTTACGGTGTATATAGCGTAGCTAAAAGCTATCAAATTTCCTGGGGTAGTTGATCGATCAGCTACCCTTAAATTTTGGCGATGCCTCATTACAGTATTTATATGAAATAAAATTGCGAAGATGAGAAAATCGCACTCGATCAACCTTCTTATTTGAGCGATCGCATTTTTGAGTCAGAATGGAGAACGCGATCGCACTATCCTTGGAGTACATTTCTTACGTTCCCAAGCTGGGCAAGATCAAGCCTGATGATTAAGCCTACCTCATTGCCTTGATTAATCCAAGATTCATACGCAGCTAGCCTTTGCTTGCCTATGTCGCTGCCACTAACCATACTCTCCATGAACTTGTCAGCCGTTAATCCAGGCTCGTCTAGCCCTATCGGCAGAATAAATACACCTCTGCTTTCAAGGGCTTTTAGCCAGGCGATGTGTTCTGATACGATCTCTGGGGCAATCACGCCAGATTTGTTCTTATTCACGCTACTAAATGACTTACGCCACGCCGTCAAGCCCTTGGCTTGTAACACGCCCCATGTGCCGCCTAACGCTGCTCCAAGGAGTTCTACTACACTCTTGACTACTGCCGCTCCCTGTGGGTCTACTTGCACATATCCCTTTACTCTGCCATTTTGCTCTCTTGTATGTAATGCCTGATAAATATCATTGACAGCAGCCAACATGTCTGCTTTATTTAAATGTTCCCCTTGCCCCGCTGGTCTTACATGCGCCCCTGCTTCATTCGTTGCTGCATTCCAATCTACACTGACCAAACCGTAGGATTCCTTATGGATTCCGCTGACCTGAGTGCTATCAAGAGCGCGTTGGACAACCTTAGACCCATGCCTGATATGCTTTTCATGCGGCTTGCCTCTTGTTGCTTTTTGAACCATCCTACCTGACTGCTGCACAACATGGGTCAACTCATGCGCCAACAACTCTTGACCGCCGCGACTCCCTGGATTATATTCTCCCTGCCGAAAGAACACATCCTGTCCCGTTGTGAAAGCACGCGCTTGAATTGACTGATTCAACTGGTCAGATTGACCATCGGTGTGAACCTTCACCCCACTGAAATCTGCGCCAAACGCCTGTTCCATCGGTTCGCGGATGTTGTCTGCGATCACCTGTCCACCCCCCCGCGCTTGGTTAATGGACGCTTCTAGGTCAGGCGCAGCAGCCATCCCAGCCTCACCCTGACTCGGCTTCATCTGTAATTCTTCCTCATCCTCTGGCAATGCTTCTCGTTGCAATGTGCGATTGTCCAGAGATTTCATCTGTAATTCTTCTTCATCCTCTGGCAATGCTTCTCGTTGCAATGTGCGATTGTCCAGAGATTTCATCTGTAATTCTTCCTCATCCTCTGGCAATGCTTCTCGTTGCAATGTGCGATTGTCCAGAGATTTCATCTGCAATTCTTCCTCATCCTCTGGCAATGCTTCTCGTTGCACCAAAGGCGTGATGGAATTTGCCAGAGGTTTCATCTGCAATTCTTCTTCTTCCTGCGGCACTGCTTCTCGTTGGATAGACTGACGATTTCCAGGTTGTGCCATTCTTTGCATTACCTGTTGTGCTACGCTATCAGCTTCCTGTTCGTAAATGTCTCCAGGCTGGCTAATTGAGAGTTTTGCTTGCGATCGCAGTGGTATGCGGCTGATATCGTGAGTAAGTGGCTGATTAAGTGGTTGTATTTCAGGAACAGTTTGGCGTGAAATTGCCGACGACTCCAAACCAAAGCCGGGTGTAGGGTGTTTCAGGGATGGAATTGAGAAGTCTGTAGTAGTTTTCTTCTGCCGGCTGACGTGTTCTCTCATTTTCTTCTCCTGTTTCCCAAGCAGTAGTTAGATGAATAATACGCTGTTACTTACATCGATATTACAGCGATCGCACTTGTAACACAATTCCTCTAAGGTAAGGGATTTTCAGCGAACGTAGGGGTGCAAGGACTTGCGCCCCTACTAAGTTCGACTTTTGGCTACTTTTGATTCTGATGCAGTACCTTTAGCCTGGATTTAGGGAGAGTTTTTTTATTTATGGACTCAAAACAGCAACAAAGTTTTTTCACCTTCGATGGAGATGTAGGCGGTACTGCTGGCTACGCTGGGGTTTCGGTGGCATCTGATGCTAGCAAGGCAGCTATTGCTGCGGGTAAATACCTCAACGATTCACGGCTGATGAACCAGCTTACAGAACGCGTATATAAACTTATGCTAGAAGATTTGCGATCGCAGCGCGAAAGAATAGGTAGTTATGATTCTCAAAGGTGGTTGTGATGGCTACAGGCGCTAACAATGGCAACATTACTCACGAATTAAATTATGTCACTACTAATCGGTTCTACGTAGAGATAGATAGTTCTATTGCTGCATCTTTCGCTGAATGTTCAGGATTAAGTGTTCAAATTAAGAAAAATGTTTTTCAGGAAGGTGGTGTTAACGACCAGCAAAGAATTTATTTAGGTCATACAGAATTTGCAGACATAACTCTTAAACGAGGATTTACCGATCATCCAGGTTTTTGGAATTGGATGAATGCAGTTTTTGATGAAAAAAAGAAAACATCTCGACGCAATGTCAATATTCTGATTTTTAATCAAGCCGGTGAAACGATGATGAGTTGGACTTTGATTGGTGCTATTCCTATAACCTGGAAAACACCAGCACTTCAAGCAGATGGAAAGGCAGTTGCGATTGAAGAATTAACTTTAGCTTATGAAGGTTTACAAGTTGCAAGGTCTACAGGAGGAGGCTCTTCTGTACAACGAGATCAAAAATCAGGATATTTCGTTTCTAGCTAATTGGCTACTCTTAAACTATCACTATGCAAATTATTCAATCTTCACTAGGAAACAATATTCATCCCCTTGGGGTAATATCATCTTTATATAATTTTCAGGGAATAATATTGAGAAAAGAATCTCATTCTTTGCATTCACGAAATAATTTTATCAGTACAATCCAAACTAAACCACCATTAGTCAAATCCTCTAAATTTTTCTTGTCTCGTCAGTATGAACCATCGATTGAACCATTAATAGGTTGGGATAGTTGGGATGCTCAGGATATAACTAGTGATTTTAGTGAATTTCCGTTGATTGAATTTGATGCTTCTGATTCAATAGCTGCATTAGACAATAGCAATGAATCAGTAAAAAATAGTATTCCAAAGATAATGCCAACTCCCATCGAGACAAATACGAGTAATGGCACATCTCAAGAAGTAAATATAAAAAATAAATCTAAGCCAAAAAAAACAAATAAATCTCAGAAACCACTAGAAAAAGAACCAAAGTCAAAATCTAGAACTAAAAAAGCTATCAAATCATCTACGGCTAAAAACTTTGAGCCAATTGTTGATAAAACTAATATTCATCTTAACAAAGATAACTTATTAATATCAGATGAGTCTATGCCTATTGAGGCTAATTTGGAAACACCAGATTTACAACTAGATATTGTGTTAGACACTACTACAAAGGATCGTAATTCTGTCAGTACTCCAACCGTAGATACTTCACCTAGCTTTCAAGATAAATCAACTTTATTCGAGAATTTTGCTACCGATGATCTGTCAGAAAATTCTGAGCTAATATCTAGTTTTTCTAGTACAGGTTTGTCTTTAACAGAAAATACTTTAACATCGAAAGAAAATATTGAATTAGACGATGGCACAAGTGAATTAGTCAACAGTTCATCTATAGAAATTCCTTCTAAAAGGAATACAGAAAAAATATTTATACCGGATAGTAACTTTACAGATAATGAAGAAAAACTAATACCTGAAGTCTCAGCATCAGTTAATCTGTCAGGTATGCAAGTTAGCCAAACGCAACCACAACAAGACATTGAAAGAGATCAGGTTCCGTCTATAGTTGACAATAAAAGCAGCGTAAGTCAGACAAATTTAATCCAAGCAAAAGAGATTTTACCAACCTTAAACTCTCTATCGCAGGAAGAAGAATCACCAAATATTAATACTAAGCTTGAGGAAGTTACAGCTATTGATGAAGCAGAATTAATATCAGAAAAAAGCACAAATAATTTTGTCACAGATAATCCTGTCTCTGAGAATTATTTAACTTTATCTTCAGCACTTACTTCATCTGAGGTTGATAATTCACATACTTTACTCCATTCTTTGGAGAATGATGAAAATACCGTAGAGACGGATGTTACTTCGTCTAATTCTGAGTCTTCAGTTGCAAAAAATCCTATTACAGTACAACAAGAAATCGATCCTGACTTTTCACACAATGTAGAAAAAGCAACGCAAAATCTAACCCCTCAGCCCCCTTTACTAGCAGATAATGGGGAGATTTTACAGCCTTTATCCTTTCAGGATCAAGGTTTTCTAGATTCTATGAAAAGTCAGGAAATTGATTCCAGTGTTACGAGTGAGTCTCCAGATATTGTGCCTGTTCAGTTAATACCTACCTCAGCAGTTATTGAAGACACACCTAGTTTATTCAGCAACCCTGATAGCGATGAACAGTTAGTAACTTCAGAATCACAGTCTGCGATGGTGGTTCATGTCTCAGATATCTCAGCAAATGTGACTTCACTACAACGTGATAGCAATATTCAAAATCCTGGTAGCGAGTTTACAGAAAGTCAACCCATCTTAGCAGCACCTGAAATTGCTGAAGCACCAACAATTAGCGCCACATCACCTGAGATTACTGAAACACCAACAGTTACCGCTATTTCCCCTGAAATTGATGAAGCATTGGTAGTTAGCGCCACATCGCCTGAGATTGCTGAAACACCAACAATTAGCGCCATTTCCCCTGAAATTGATGAAGCATTGGTAGTTAGCACCAATTCGCCTGAGATTACTGAAATACCAACAATTAGCGCCATTTCCCCTGAAATTGATGAAGCATTGGTAATTAGCGCAAGTTCGCCTGAGATTACTGAAATACCAACAATTAGCGCCATTTCCCCTGAAATTGATGAAGCATTGGTAGTTAGCACCAATTCGCCTGAAATTGCTGAAACACCAATAGTTACCGCCACATCACCTGAAATTGATGAAGCATTGGTAGTTAGCGCCAGTTCGCCTGAAATTGTTCAGAAAACAAGTATTTTTAGGGAAATTATTGATAATGAAAAAACAGTAGAATCAGAAAATCCTGAAATATCAACCTTTGCTGATACCTGGGATAATCCAGATATTCTAGACAACCCAACTTCTCCACAAGATGAGGTAAGCACAGCACCTAAAGTTGAGCAAAATGCGATCGCAGAAAATTTGCCCGCGCCTAAAGGTTATGCTACTGGTGGTCATGTTACAGACTCCCGTGTTGAAAATCGCCAGCAGATAGCACCCTCCGATACAGTACCTGCAATGCTTACGCCTGGAGAGTTTGTGATTAATACCAGGGATGCACAGAAGAATCTACCCCTACTACATCACATCAACACGGGTGGAACACCGCACGATATTATTCTTCCAAGTTTACAAACACCCAATCCCATAGAACCAGAAGCAACAATTTCTCCAGAGACTCCGACTAAAGTCGATTCTTTTTCAGACACTTCATTACAGCTAAAAAGCGCTGAGACTGATTCACCTGAGATATCAAATTCTTTAATTCCTTCTTCCTTCGGGTTGAATAGTAATAAACAGAAACTTTCTATCCTCAATTATCCCCAGCTTCATACTCTTCAAAATGAAACAACAGATGTCGGTGAATCTTCACCTCAATACTCATCGCCTCCCCTGATTTTCCGAAAAGCAAATTCCAGCACACATACGCCTTCCCAATGGTCAGATACACCTTCTCAATGGTCAAGTGTAGAAGATTTACTAAATGGAAATAATGATGATTTTACTAGCTTTAATTTTAATGATGGGGAATCAAACAGTCAAAATTATGAATTTTCTCATGTTTCAGAATCGCCACAAGTTTTTGCTAAACACCTTCCTTCACCGAGAGGCTTTGCTAATGGTGGAGAAGTCACTCCACCCGACATATCTAGAGAAATACAACCGATAACTGAAACCATAGAGAGTGTATCCTCATCTTCTCTAGGAGATGAAAAAGATGATACAGCTGATTTGGAAGCTCTAGCTCGTGAAATTTATCACAGATTACGACAACGGATAGAAATTGAACGAGAGCGTCATGGCGGTTACTCCGGTCGATTACCTTGGTAAATTTTCATTCAATAATTAATTTTAGGAGAAATATTCAAATGGCAAGTCCAGCAATTATTGTTATTCAAAAGCTTAAACCACAACTTGAGAAAGCCAAACTTGTAGCTTATAACAATGAAGCGCCAGATATTGAATTAATGTTTAATCCTACAGATATTAGTTTTGCTCGGACTGTTAAGTGGGAAAGTAAGGATGGGAATAGAGGAACCACTCTACTTCCGAAAGTAAACTTTTCTGGCGTTGAACCTTACAAATTCACCCTTAAACAGTTACTCTATGATACTTATGAAACGAAAGAGTCGGTGATGAAAAAGTACATAGATAACATTAAAAAAGGTGTAGAAACTATCAGTAAAGCAACTGATAAACGACCACCTGTTTATATATTTACATGGGGAGATGAATATTTTTATTGTGTAATCACGAGTTTAACATACACTTTAAATATGTTTTTGAGTGATGGTACACCAGTCAGGGCACTGGTAGATATAGCCTTGCAAGAAGTAGATAAAAATAACCTGCCTGGAGGACGTAAATCTGATTCTAAAGGCAACGCTCGTGCAACAGATAAAAAGGGTCAAAAGCTGAGTAAGTAAAAGATATAAAGTAATAAATTAGTATTTACTTTGTCATTAAAGGCTGCTCTAAACATTTTATAAATTATCAAATAATAGTTATGCCTCCTAAAAAAAGCCTTTATTTAAGCGAACCTAAAATACAGATAGATGGACAACCTGCTTCTCCTGAATTAATGAAGGATTTGTTGCAAATCACAATAGAAGAAAGCCTTCATTTACCAGCAATGTTTACGCTAGTAATCCATAATAGCTATATTCCCACATCTGACCGACCAGAAAATAAGGCTTGGCGACATGAGCAGTTGTTTAGAATTGGCAAAAAAGTGAAGTTGGGTTTTACTTCGAGTACTACTCTAGATAATAATTTTCAAGATGAGGTAGAAAAAATCCTAATTGAAGGCGAAATTACCGCGATGGAAGTTCACTTCAATGAAAAATCTGAAGCTGATATCATTGTTCGTGGTTATGATATTTCTCATCGTCTTCACAGAGGTCGTTATAATCGTTCTTTTTTGAATGAAACTGATAGTGATATAGTCAAAAAAATAGTTCAGGAAGTAGGTATAAGACCTGGCAATATTGATTCAACAGGCGAAGTTAATAAGTATGTTTTTCAAGAAAACCAAACTAATATGGAGTTTCTACGGGAAAGGGCAGCCCGTAACGGTTTTGAACTATTTATTACAGAGGATAAGATCAATTTTTGTAAACCAAAAGTTCAGGAATCTCTAGCATTAGAATGGCTAGATGATATTAGTAAATTTAGTACCCGCGTCACCAGTGCTGAACAGGTGAGTTCTGTGGAAGTACGTGCCTGGGACTATACTCAGAAAAAATTGATTAGCCAAACAGCTAACAAAGAAAAGCAAGTAACCGAGACAGGTAATCAGCTAGGAAGTAGTACCAGTACTGCATTTTCTAATCTTAAGTCTCCCAAAATGATTGTTGTAGATAAGCCTGTCGCCAGTCAAAAGCAAGCAAAAGCTATGGCTCAGGCTTTATGTGATGAATTGGGAGGAGAATTTGTTTATGCAGATGCTAAAGCAGCAGGGAATCCTGAGATTCGTCCTGGACGAGTTGTTAAGCTTCAGGGTATGGGCGATCGCTATAGTGGTAAGTATTATGTTACAGAAACCCGCCATTTCTTTAATCAGCGCGTTTATGAAACTGAGTTCAGCGTGCGGGGACTACGTTCTGGTAACTTATTCACAACCCTATCTCCAGAAAAACGTCTACAGCCATCTGAGACTTTATTAGTGGGAATTGTGACTGATAATAAAGACCCAGAGAAAATGGGCAGAGTGAAGGTCAAGTTTCCCACTCTCACAGAAGACCATACAAGTGACTGGGCGAGAGTTGTAGCTGTGGGAGCAGGCCCAAACAGAGGTTTTGACTGTTTACCAGAGGTAAACGATGAAGTTTTGGTAGGTTTTGAACATGGCGATATCCATCGTCCCTATGTCATTGGCGGGGTATGGAACGGGAAAGATGCACCACCGGAAAAGGTGAGTGATTCGGTTACAGGTGGTGTCAGATTACGCACAATTAAAACTCGTGTTGGTCATGTTCTACAGTTTGTTGAAGAGGATAAAGGAAGTAGTAAAAAAGGTATTCGCGTAGAAACCACAGGCGGTCACAAAATATATCTCAATGATAGCGATCGCTGCATAGAGATTGAAACCACAGGTGGTCATAAAATCAAAATGGACGATATGGGTAAATCTGTTTCAGTGAAATCAACAGGTAATATGTCATTAGATGCTGCTGGAAATATAGACATTACAGCCAACGGCGTGATTACAGTTAAAGGTGCGATGATTCGCCTTAATTAATTTTCTATGTTTTTTCTCAGCGCTCTCTGTGCCTCTGTGGTTTAAAAGTAATTTATCTAACCACAGAGACGCAGAGAACACAGAGGTAAGAGATTAAAGACACTATTAGGAGGTTGTGATGGGTAAACCGGCAGCAAGAATTACTGATAATGTGGCGCACCCTTTACCCCCAGTCTTAACAGGGGGGCCGGGTAGTCCCAATGTATTGATTGGATCTTTACCTGCGTGGCGGGGTGTGCTTGCAGCAGCAGTACCAGCTTTACAATCCGCCAAACAAATTTCTGATACGGCTATCCAAGTGGCTGAGGCTGCTACCCTAGCGGCGGCAGGTACACCAGGGGCACCTGCTGCTTTAGCCGCCGAACAAACTACAAAGGCAACATCAGCAGCTACTATGGGTAGTGCGATCGCAGCAGCAGCAGCAGGAGCTGATATTCATAATTGCGCCACACCTTTACCCTTACCTCCTCACGGCCCTGGGGTTGTGATTGACGGTAGTCAGACTGTGCTGATTAACAATCTACCCGCCTCTCGGATGGGTGACACTGTTTTAGAAGCATTAGGGCCGCCGAATAAAATTATCAAAGGTGATTTTACCGTTTTGATTGGCGGCTGATTGGAGAGGCAGGGGGAGAATGATTTGTAATTGTAATTTGCCATAAATTAAGATTCATAGATGAGTCTTTTTTACTCATGGACGAGTCTTTGAACTCCTTTAATGAGTCTTTGAACTCCTTTAATGAGGCTCAGAACTCCATTAATGAGTCTTTGAACTCCGTTAATGAGTCTTTGAACTCCATTAATGAGACTTTTTTACTCGCGGACGCAGCATAGATTCAAACTCCATTCCCCATTCCCCATTCCCCATTCCCCATTCCCCTATCTCCTCAACCTCGACCTTTGGCGAATAGGCTTAAACCTTCTGTGTCGATATCTTTGAAGATATCCATGTACAACTGTCTAAGTGCCAGATATGGTTTACGGTCGTGAACGAGCCTATTTGGGAACAGGTTGGGCTTATCCACTGCATTTAAGTGTGCAAGGCGGGATACAACTTAGCCGTGAAGATCAAAAAGTTAAAGAATCTATTTGGATTATTCTCCGCACCGGAGTAGGTGAGCGGGTTTATCGACCTACCTTTGGTTCGCGCTTGTCTGAACTGGCGTTTGCACCTTTAAGTAGCGATACCCTACTGCGAATCCGTCTTTATGTCTTGGAAGCTTTAGAAGTTTGGGAACCACGCATTACTATCGATGAAGTTGTCACCGATCCTGACCCTGTGCGTGGCAGAGTGGACATCATTATCAATTATCGACTCAAAGACGGCCCCGATATTTATAGTTTTGTTTATCCTTATTATTTGGTTTCAGCTGGGGAGGAATCGTGATCCGAATTAAAAATTGAAAATTAAAAATTAAAAATTAATACGACTTACGCAAAATATCTCTCAAACTCTGATTTCTCTGTGCCCTCTGTGCCTCTGCGGTAGCCTGCGGCAAGCCGAAGCGTCTACGTTATTCCGTAATTTATGCGTAAGTCCTAATTAAAAAAGCTGAATTTTCTCTGGGTTTCTAGGCTTGTATCTGTCACATTCTTTTTAAAATTGGTATGAACTTTGATTTTTTACCGAAATTACCTTCTTCCAACTTAGACGATCGCGCCTTCGATGATTTGGTGGAAGAATGTATTATGCGTATTCCTCGCTACTGTCCAGAATGGACAGACCACAATCTCAGCGACCCAGGAATTACGCTAATTGAGTTATTTGCTTGGTTAACTGACCAAATGTTGCTCAGATTTAACCAAGTACCCCGAAAAAATTATGTCGCTTTCCTAGAATTACTGGGTATTCGTCTCCAGCCTCCCGCCCCAGCCCGCACGGAATTAACTTTTTATTTAAGCGCTGCATTACCCGAAGCCTACACAATTCCAGCCGGATTGGAAGCCTCAACTATCCGCACTGAAACTACAGAAGCTATTACCTTCAGCACAGATTATCCTCTAATTATCGGCAATCCCCGCATCCAACATTTCTTAACTGCCCAAACTACCGAAGATATTCCCCAATCTCTGCGCGAAAGAGTCACAACTTCATGGACTCGTCAATCTAACGGTTTCTGGACAGGTAATGAACAACCGATTTTTGAAGAGGAACCCCAGCCTGGTAACTGCTTTTATTTAGCCATTAATTCTGATGATCCTTTAGATGCTAATGTTTTAGAAATTATTTTCCAAGGGGCTGCGGCTACCCCTGCTGGTATTAACCCCAATCAACCACCGCGCAAATGGGAAGCCTGGGATGGGGAAAATTGGCAAGCAGTTTTATTGCAAGAGTCAGATGATAAAACTCGTGGGTTCAGTTTTTATGAAATGGCCCAACAGGGTGGAAACCCATCTCAAGGTGCAGAGGTACGTTTACATCTACCTCAAATTTGGCCTGTGGCTAATTTTACCTCTTACCGAGGTCGTTGGTTGCGCTGTAGCTTTGTTTCCGCAGAAGCCAATGAAACTGGTTACAATCGTCCGCCAAGAATTATTGGTTTAGCAGCGCGGTCAATTGGCGGTACTGTTAGGGCTAGTCACAGTACGCTGATTATAGATGAGCGATTGGGAATTAGTGATGGTACACCCGGTCAGAGTTTCCAGTTACAAACAGCACCAATTTTAGAACGTCGGGAAAATGAGTATATTTTAGTTACTCCTAGTGGTGGTTTGCCTCAAAAGTGGATTGAGGTGAGAGATTTTGCTGATTCTGGGCCGCATAACTTTCATTACACCATCGATTCGATCACTGGGACAATCCAGTTTGGGCCGCTGATTCGGGAACCTAGCCAACTTAAACAGCATACCCAAATGCGATCGCGAATCCAAGAACCATCGCTAGATAACACATCTGTACAAGTTCTAGAAAATAACCAGTCGGAACACCAATATGGGGCGATTCCTCCCCGTGGTGCAGAGATTAAAATGGTTGCTTATCGCACAGGTGGCGGTAGAGAAGGCAATGTGCAAACTGGGGCAATCCAGTTTTTGAAGTCTGCATATCCATACATTGCTAGTGTGGTCAATCGTGTACCTGCAATCAATGGTGCAGATGCCGAATCGCTAGAACAGGCTGTAATGAAGGCTCCCCGCATCCTTCGCACACGCGATCGCGCCGTCACTGCTGAAGATTTTGAAGTTTTGACTCAACAGGCGGGTGCTGGTGCGATCGCGCGCGTCCGGTGTTTGGCAGCGAATTCTCGTAGACAAGCTGGTATAGTTAGTTTACTGGTAGTACCTTATGCAAATACAGATGCGATCGCGCAAGGTAATGGCATGACACCAGAAAATTTTGCTCTTAGTAATGCCCTGCAAGAGCAAATTATGAGTTACTTAGATGAAAGACGATTATTAGGGGTACAAATAGAATTACAAGAACCGAATTATGTAGGTGTTTCTGTACAGACAGAAATTGCTTTAGAACCTGCTTATGATAATCCTTTTGCCAGAGAAGAAATTCGCCGGAATTTAAGGGTATCACTGTATAAATATTTAAATCCATTAACGGGAGGAATGGACGGCAAAGGTTGGCCATTTGGGCGACCAGTTTATACATCAGATATTGTCGCATTACTGCAACAAACCCCAGGTGTGCGTCATTTAGGCCCTGTCCTGCTGTTTCCCATCCGCAAGCAAGGAGAAAATTGGCGACGACAACCATCACCAGAACAATTAATTGACCCAGGCTCGGAAGGTTTGATATGTTCTTGGGCTGATACCAATCTCCGCTCAAATCACGACATTCAAATAATTCGTAATTCGTAGTTTGTCATTTGTCATTCGTCATTTGTCATTCGTCAGTAGTTATTCCCAATTCCCCATTCCCCATTCCCAAATCCTATGGTTCAAAGTCGCTCTAGTCCAGCTGTAAGCATTCAATTAACACCAATGCAAATACCCGAGGCTTTACCTGTGGCAGGTTTAGGATTTGCAAACGCGGATATGGATGTAGCTGGACGTACTTTACTCTTGCATCCTGGGCATCCCAGCGAGATGATTGTGCAAGTACAAAACTTAGAACAACGTCCTTTGCGGGTAAGCTTAAGTGTTGAGGGAAACTTTCCATCTCAATGGTGTCAAATTGGCACAGAGGGTAGTGAAATACCGCCTCGTGGACAAATGGATGCTGTTCTCTACTTCTCAATTCCCGACACATTTTTTGAAGACCAAGAAGCAATTTCTCCTGGAACAAAAGATAAATTAACTCTCAATTTTCGTAGTCTAGTTACTCTACATATAGACCCAGGTACCGACAACGAACAAATCGAGAGAAGCGAATATTTCGATTTATATATCCGTCCCTACACCGCCTACATGGAATTCTTGCCAATTTTGTATCGAGAAGTAGACTTTATTGGTCGCTTCATGAAGATATTTGAGCAAGCTTTTCAACCAATAGTTGATAGTTACAATGTCATGTGGGCAAACCTCGATCCTTTGACAGCGCCACAAGCATTACTACCTTTTATGGCTCATTGGGTTGCTTGGCAAGTAGATTCTGTGTGGGATCTCCAGCAACAACGGCGTTTAATTCGTCGCGCTGTAGAACTTTATCGCTGGCGCGGAACTCGCAAAGGATTGCGTCTCTATTTACATCTTTATACTGGTTTACCTCTAGACGAACATTTACCAAATGAAGCTGATAAACATATCAGTATCACAGAACCTTTTGGCCCAAGTTTCATCATCGGAGATGCCCAATTAGGAAATGCAGTTTTAGCCGGTGGGCAACCATATCATTTTATAGTACGTTTGCGTTCAAATATTTCTAGTGGCATCATCAACGAGCAACTTATCCAAAGAATTATAGAACAGGAAAAGCCTGCTTTCTGTACATACGAACTATCTATTGAAAATCCCACTCATTAA

Protein sequences of DBSCAN-SWA_7

>NZ_CP046703|6595657:6628147|6600276_6602457_-|WP_114082352.1|DBSCAN-SWA
MLTNLKTLFRQPVILSSAIATILLVGIQKLGVFEPLEMKVYDQMMQLRGDPGPDSRLLIVALTEKDIQKWNWPLSGELLDRLLGKLEAYEPRAIGLDIFRDLPVQPGHEKLLQRLQQSDIIIPICKHSGSNNPGIPAPKGIEAERVGFNDVVEDTDATIRRNLLLVSAEESDSCQSTYSFSLQLALKYLEVGGIQLKFTPKKELQLRDTVFKPLQSDAGGYQKADTNGYQILLNYHSGHQIAQKVTITEILENQVKPDLVKDRIVLIGSTANSLNDIFNTPFATGKSDNSGKMAGIEIHAHSVSQILSAVLNKQPLFWFLPEWGKVLWIWGWTVVGGLLVSRIQHPLGLGLAGATALAVLFGGNFVIFTQAGWFPVIPPTLGLVFTAGSVLAYSAYKTKQEQQEITQRVQEHQQLIVELQGLLRQRGDASNEAPTVIADSIGQEISLGTLLNNRYKITQGLGSGGFSNTYLADDIQRPGNPQCVVKQLRPPRQDAEYLNVVRRLFDAEAQILETLGKHPQIPQLLAFFEENRQFSLVQEFVRGHAMDKEVTSGKRLKQAEVVEMLKEVLHVLVFVHSYGVIHRDIKPSNLIRRESDQHIVLIDFGAVKQIHPQQQEAQTISIGTPGYAPSEQMSGLPKLNSDIYALGIMGIQGLTGVDPREYRRDVNTGEIIIQGGADGNQQTWQHWRELTEATNELVIILNRMAHFDFTQRYQSAAEVLKALESL
>NZ_CP046703|6595657:6628147|6606843_6608505_-|WP_114082348.1|tail|DBSCAN-SWA
MARLDYFAPGVYIEEIDRGSRPIEGVSTAVAGFVGFTEDVRGGAELYKPMLVTTWTQYLNYFARPNSDGFTDFNAYLPFSVYGYFMNGGGRCWVTSIGTQLPGAPRPATPEPATLRINSRGNRPALRFTLRPEQASGGLVNLVIIDGSPRALPEGTEGEAPPNTGEYFTIQIRRGDELLEQYENLTMNREPAAQIATYALAALRNSMYVSVEDITQSGQPLARRPVNGQYELAPPIVAAPPDRFSQNLEGVRDDRTGVRGIFEVDEITMLACPDVMRAYQEQILNLDQVHGIIELMISMCEGSASGDIPNPPNRMVVLDAPPDAVKPQQVVEWLNRFNRRSMFAALYYPWIKVPNPRDRGNPILVPPCGHVMGVWARTDETRGVYKAPANEVPRGVIGLGYDTNFREQELLNPLGINCIRNFPNRGIRIWGARTLVEPDKTEWRYISVRRLISYIEKSLELGTQWVVFEPNDQDLWARVTRTVSNFLERIWREGALFGASPAQAFYVKCDEELNPPETRILGRLYIEVGVCPVRPAEFVVFRISQWNGIEDNE
>NZ_CP046703|6595657:6628147|6608535_6609375_-|WP_114082347.1|DBSCAN-SWA
MLIFVLQTLAEILAGGTSLTSTEQIDFSHPGNRREEGAGPTLNLYIFDIRESKQVQHSGRQVERKLTRALQPATVNWAPAWFDVSLLLTAWDRTALGEHHFISEALAVLLRHRTLEEEFLVPELRGYGNLNMTVALEPPIEIGSLWSALNVPLRSALYLTVTIPFEPQPTPVPLVWERIFNLRNQLSRDSDSLVLTRRVAIAGIVKSAVTNLPLVATEVAVRGTEKSISTTKEGLFFFEDLHLGNYVLTLNHPGYLPQNVNALVDNQSNTFKEIFLTPE
>NZ_CP046703|6595657:6628147|6597752_6598526_+|WP_114082354.1|DBSCAN-SWA
MALSITHLFTKVKPGSAMVELKTLNLKLGHGIEEDINAELISPRQVLIVRYEDILDLSIQPGELRENIVVTGIGFDKFIPGSLLTFESGAAIRLTFYCEPCKRIAHLVESFKSIKGKRGILGVVTQSGQIQVGSKFQVQAQKFPALPENPYERFLDFIIKIPSGKVVTYKQIIKAIGVDNSYLRAIPTYLKKTSANNYPVHRILDSKGYLINYVNQQKDKLETEGVKVLAEADVVKKLNKNYVDINNYSWEDCNIYL
>NZ_CP046703|6595657:6628147|6624209_6624623_+|WP_114082336.1|DBSCAN-SWA
MVYGRERAYLGTGWAYPLHLSVQGGIQLSREDQKVKESIWIILRTGVGERVYRPTFGSRLSELAFAPLSSDTLLRIRLYVLEALEVWEPRITIDEVVTDPDPVRGRVDIIINYRLKDGPDIYSFVYPYYLVSAGEES
>NZ_CP046703|6595657:6628147|6614041_6614689_+|WP_114082343.1|DBSCAN-SWA
MPANRCPNPSCEYFNRALPNNAKVCPWCSTPVGNVVSSTPQQPPSQPPPIQQQPSQPPPAQYQRPPTEQPNYQPPQQPPVDYSTVYQPRVSYQPTPPAYVPPPQRAPALKLIHTTGREFHLVGEGGYIGRRSQSPGIAPPEIDLTGIPSEGIVSRRHARVDWDWSQNAYMIVDMSTNGIYLNNNPLTPGMQYRLLNGDSLRFGQDNLVNFTVYIA
>NZ_CP046703|6595657:6628147|6598601_6599330_-|WP_114082353.1|DBSCAN-SWA
MLKLSPESPLFFVLIIISFLIVTLSTWLLSKPFILKPFGLNDIIQILTLQLFISLLLERSLEVFITTWRGPFVEQLDISIQQEKALISEKLRLIEVQQKQFPSFESNQSIGLPPEGMSLEQQIIQNFTQNQQESLKIFKPQMDNLNEKERKKIAYKSDTRVIALWTSLLFGLLMSAIGIRSIEPLVVLDFDNPIQVIIFRCLDALLTGGLIAGGSEGIHKLIKVFIDFMEATSKQIKNQGLS
>NZ_CP046703|6595657:6628147|6620864_6621422_+|WP_114082339.1|DBSCAN-SWA
MASPAIIVIQKLKPQLEKAKLVAYNNEAPDIELMFNPTDISFARTVKWESKDGNRGTTLLPKVNFSGVEPYKFTLKQLLYDTYETKESVMKKYIDNIKKGVETISKATDKRPPVYIFTWGDEYFYCVITSLTYTLNMFLSDGTPVRALVDIALQEVDKNNLPGGRKSDSKGNARATDKKGQKLSK
>NZ_CP046703|6595657:6628147|6604746_6605130_-|WP_114082360.1|tail|DBSCAN-SWA
MRRKKDTLCTEFAFTLPRGLSDNEHRVHRHGVMRLATAKDEILVQQERRVQENPAYGVLVMLARVITRLGSLNSVSPDLLEELLLHDIAYLREFYNRINQEGDVHIPTQCPHCNTQFSVELELAGES
>NZ_CP046703|6595657:6628147|6606164_6606620_-|WP_114082349.1|tail|DBSCAN-SWA
MAGEFLTSCKFYFEADGITDKFIKEISGLGVENTPAQEVHGSSKGAKLMRQATPTVVKFTNITVKVIATDDIDLYTWYQKCNEDMGDPRQWAQNRKTGSVVAYDQQGSEKARWNIVNCYPCKYTGPTLTASGGDMANETVELVHEGIKRIK
>NZ_CP046703|6595657:6628147|6599702_6599921_-|WP_147262512.1|DBSCAN-SWA
MKLSILIDSVLIVTSIALLPGMGGAQIVTHNSGEPIAVNSKNLPTHSTNVSDPIPFDVAFLAHQGGKASVYP
>NZ_CP046703|6595657:6628147|6611207_6611888_+|WP_114082345.1|DBSCAN-SWA
MANDSKKLSVLLVDDEERFRQGLRTLLNFYSINSALPVEVIGDADSVEQVLKFTAQKCPDLILLDMQLKGCDGITVLARLKETAYTGKVLVLSAHQEDDWIFRAMQAGAAGYVFKNRVATQLCEAIDTVTRAEIYLPSEVASRFFRFFQAYSDSCLKACHEVHLTEREQEVLYWLTQGASNEEIAKHLYVTVATVKAHLTSIFEKLKVTSRTQAIVAALKLGLVHA
>NZ_CP046703|6595657:6628147|6624844_6627043_+|WP_114082335.1|plate|DBSCAN-SWA
MNFDFLPKLPSSNLDDRAFDDLVEECIMRIPRYCPEWTDHNLSDPGITLIELFAWLTDQMLLRFNQVPRKNYVAFLELLGIRLQPPAPARTELTFYLSAALPEAYTIPAGLEASTIRTETTEAITFSTDYPLIIGNPRIQHFLTAQTTEDIPQSLRERVTTSWTRQSNGFWTGNEQPIFEEEPQPGNCFYLAINSDDPLDANVLEIIFQGAAATPAGINPNQPPRKWEAWDGENWQAVLLQESDDKTRGFSFYEMAQQGGNPSQGAEVRLHLPQIWPVANFTSYRGRWLRCSFVSAEANETGYNRPPRIIGLAARSIGGTVRASHSTLIIDERLGISDGTPGQSFQLQTAPILERRENEYILVTPSGGLPQKWIEVRDFADSGPHNFHYTIDSITGTIQFGPLIREPSQLKQHTQMRSRIQEPSLDNTSVQVLENNQSEHQYGAIPPRGAEIKMVAYRTGGGREGNVQTGAIQFLKSAYPYIASVVNRVPAINGADAESLEQAVMKAPRILRTRDRAVTAEDFEVLTQQAGAGAIARVRCLAANSRRQAGIVSLLVVPYANTDAIAQGNGMTPENFALSNALQEQIMSYLDERRLLGVQIELQEPNYVGVSVQTEIALEPAYDNPFAREEIRRNLRVSLYKYLNPLTGGMDGKGWPFGRPVYTSDIVALLQQTPGVRHLGPVLLFPIRKQGENWRRQPSPEQLIDPGSEGLICSWADTNLRSNHDIQIIRNS
>NZ_CP046703|6595657:6628147|6614864_6616151_-|WP_167756026.1|DBSCAN-SWA
MKPLANSITPLVQREALPEDEEELQMKSLDNRTLQREALPEDEEELQMKSLDNRTLQREALPEDEEELQMKSLDNRTLQREALPEDEEELQMKPSQGEAGMAAAPDLEASINQARGGGQVIADNIREPMEQAFGADFSGVKVHTDGQSDQLNQSIQARAFTTGQDVFFRQGEYNPGSRGGQELLAHELTHVVQQSGRMVQKATRGKPHEKHIRHGSKVVQRALDSTQVSGIHKESYGLVSVDWNAATNEAGAHVRPAGQGEHLNKADMLAAVNDIYQALHTREQNGRVKGYVQVDPQGAAVVKSVVELLGAALGGTWGVLQAKGLTAWRKSFSSVNKNKSGVIAPEIVSEHIAWLKALESRGVFILPIGLDEPGLTADKFMESMVSGSDIGKQRLAAYESWINQGNEVGLIIRLDLAQLGNVRNVLQG
>NZ_CP046703|6595657:6628147|6609449_6609611_+|WP_159402592.1|DBSCAN-SWA
MSIFLDWGLGIGNWGLGKTVPLADSSGLAREELGVTNSPPAPNGTLVNRKALI
>NZ_CP046703|6595657:6628147|6616939_6617464_+|WP_114082341.1|tail|DBSCAN-SWA
MATGANNGNITHELNYVTTNRFYVEIDSSIAASFAECSGLSVQIKKNVFQEGGVNDQQRIYLGHTEFADITLKRGFTDHPGFWNWMNAVFDEKKKTSRRNVNILIFNQAGETMMSWTLIGAIPITWKTPALQADGKAVAIEELTLAYEGLQVARSTGGGSSVQRDQKSGYFVSS
>NZ_CP046703|6595657:6628147|6611931_6614070_+|WP_114082344.1|DBSCAN-SWA
MPSFESFYQEYPCSYNSPLSCDRPFQTAQQIKGAKFCLECGFPATLPQEAEIKGSQGTYQIASFIGVRGLGRLYSGVQLKDKQPVIIKEYLLPNRCFNESETLKRKETFKRVGGVSLADSRIQNFRLVETKEAIADEKGERCYLITQGIESSQTLGKYLIEKGAMTSIDVREVLNQSLQTLQFLHTQKLRFPSNQVQLGITHGNISLDSTLIKLENNQKFSIYFCDLATWENLFIPPIIPQPAPARPEQDLESLGLLAFYLWTGRTTNFLSNQPLDPRDNQQWPDTDSHLKQFIYRLIGLETPFENAETARQALLQLPKEERGKSSVSSPASQAIEKRLPMPLILIGILALLLLGGGILYWFLGKKTDSPNQYILWSRLVRNFSEVPNVPAGQFTYTGEKDSTWSYVLTQSVENSRLGELLTRPKPDATATFNYQSVLSANVKNPIKSIEEVETNKKDFAITSLVDNITDKLSKKQVAYDGLIVFVAFNKRDSNLANALGGQISLEQLRQIYTGKITNWQQISPKLPNLAVKPFAPTEPEAISKFQEIVLKNVPQDEALFAANVTKLDTTKTQNQIRSETLDGRTTGIISFGIISKTSSQCTGYPLAIADGKKSAIQPLFQRRDRRSINPSDDLCQHDDYYVDVTTFQSYPLGYPIFVVYPKDTSRLPGGSTFAQMLTTRQGQCLLSKVGLVALQPMPDDINSYACKSVPQS
>NZ_CP046703|6595657:6628147|6605647_6606142_-|WP_041565926.1|tail|DBSCAN-SWA
MVQSASRIPEVLTAHRFYLELTLEGQNDANCFFLECQGFKRTQEVIEISEVTSQTWGKKGQSKGQVVRTKLPSNPKSGNLTLRRGTTNSMDFWKWFEKVEKGNWSEQRRLVALSIYNQANQEIARFELAGAWPASYKIADVNARSHDIEIEEVEVAFEEFKRVK
>NZ_CP046703|6595657:6628147|6610062_6611184_+|WP_114082346.1|DBSCAN-SWA
MTLGFYVQKLENGSNYLNSSDIQSYCQLESEQLTSQYPIFFARIVYHDYLLKNHQEVINYGQDQAPFSHKTLAYLRSEAWLTDFPPALTLHEFKLKDFSSISYICPIGYKNQKPEYIQIITHKPLSESLQLYVKRSAMLLSKYADIYLDYGRQKTEIQLLEDILHRIGHQLRNALGLIGLYAHNLCLGLEDSPWQEQATIIGESIQDLDTNLNELIDCGQSAKLRVKLQDLRSLVYESIKNLQPLINQKKLKILIPDTSTILKIDKLQMKQVFDNILSNAVHFSPNSGTITCSWQVFQDEVLIKISDQGPGLSQEDLQKVFTPFYSRRKGGTGLGLTIAKKIILDHQGSIWAQALSENGAQFSVILPRPRSMN
>NZ_CP046703|6595657:6628147|6623354_6623852_+|WP_114082337.1|DBSCAN-SWA
MGKPAARITDNVAHPLPPVLTGGPGSPNVLIGSLPAWRGVLAAAVPALQSAKQISDTAIQVAEAATLAAAGTPGAPAALAAEQTTKATSAATMGSAIAAAAAGADIHNCATPLPLPPHGPGVVIDGSQTVLINNLPASRMGDTVLEALGPPNKIIKGDFTVLIGG
>NZ_CP046703|6595657:6628147|6621502_6623236_+|WP_114082338.1|DBSCAN-SWA
MPPKKSLYLSEPKIQIDGQPASPELMKDLLQITIEESLHLPAMFTLVIHNSYIPTSDRPENKAWRHEQLFRIGKKVKLGFTSSTTLDNNFQDEVEKILIEGEITAMEVHFNEKSEADIIVRGYDISHRLHRGRYNRSFLNETDSDIVKKIVQEVGIRPGNIDSTGEVNKYVFQENQTNMEFLRERAARNGFELFITEDKINFCKPKVQESLALEWLDDISKFSTRVTSAEQVSSVEVRAWDYTQKKLISQTANKEKQVTETGNQLGSSTSTAFSNLKSPKMIVVDKPVASQKQAKAMAQALCDELGGEFVYADAKAAGNPEIRPGRVVKLQGMGDRYSGKYYVTETRHFFNQRVYETEFSVRGLRSGNLFTTLSPEKRLQPSETLLVGIVTDNKDPEKMGRVKVKFPTLTEDHTSDWARVVAVGAGPNRGFDCLPEVNDEVLVGFEHGDIHRPYVIGGVWNGKDAPPEKVSDSVTGGVRLRTIKTRVGHVLQFVEEDKGSSKKGIRVETTGGHKIYLNDSDRCIEIETTGGHKIKMDDMGKSVSVKSTGNMSLDAAGNIDITANGVITVKGAMIRLN
>NZ_CP046703|6595657:6628147|6616700_6616940_+|WP_114082342.1|DBSCAN-SWA
MDSKQQQSFFTFDGDVGGTAGYAGVSVASDASKAAIAAGKYLNDSRLMNQLTERVYKLMLEDLRSQRERIGSYDSQRWL
>NZ_CP046703|6595657:6628147|6595657_6596880_-|WP_159402613.1|transposase|DBSCAN-SWA
MQLTDSLKKLLKETAHQLKGAAKRRFIAQTVVALGHGGKSIAERELGWNRVTIGKGIKELNSGITCVDNYQGRGRKKAEEHLPTLLEDIKKLVDSQSQIDPTFKSQRLYTRLGASVVRHQLIEKFGYAEEELPTSETIRVKLNDLGYRLKRVAKIQPQKKFPETDAIFEQLAIVHQEASDDPTILRLSLDAKARVNIGSFDRGGRNRVPTETDDHDFKPKTTVAPYGIFLPDLDELFLYFTESKVTSDFIVDILGDFWKSESWRFSEIKTLLINQDNGGENSSRRTQFMKRIVEFAQSYKLNIRLAYYPPYHSKYNPIERTWAVLENHWNGSILDDVETALNFAKTMTWNGKSPVVKLVTQTYSSGVRLTKKAMQEIENKIERLTNFTEDNLPNLGKWFIDICCGVT
>NZ_CP046703|6595657:6628147|6597062_6597728_+|WP_114082355.1|DBSCAN-SWA
MCDRYLAHVLLKEKLQAKLEEIQAKSDGSPVTDLKLDKTLAEEIEKLTTELESVNPNLNPLSNATHLLNGAWQLQYSTAREIRSLASLPLGLKLGKVYQVIDVTNKLFFNLAKVKHPLGIVSGYVKVTASFGPAKEDLEPLANKRLNVYFDKRYLSIEQIVGINTPQLNPFKVVSANNPTSRVATLDITYLDETLRIGRGGDGSLFILSKSDDLPDFTSSI
>NZ_CP046703|6595657:6628147|6617487_6620826_+|WP_114082340.1|DBSCAN-SWA
MQIIQSSLGNNIHPLGVISSLYNFQGIILRKESHSLHSRNNFISTIQTKPPLVKSSKFFLSRQYEPSIEPLIGWDSWDAQDITSDFSEFPLIEFDASDSIAALDNSNESVKNSIPKIMPTPIETNTSNGTSQEVNIKNKSKPKKTNKSQKPLEKEPKSKSRTKKAIKSSTAKNFEPIVDKTNIHLNKDNLLISDESMPIEANLETPDLQLDIVLDTTTKDRNSVSTPTVDTSPSFQDKSTLFENFATDDLSENSELISSFSSTGLSLTENTLTSKENIELDDGTSELVNSSSIEIPSKRNTEKIFIPDSNFTDNEEKLIPEVSASVNLSGMQVSQTQPQQDIERDQVPSIVDNKSSVSQTNLIQAKEILPTLNSLSQEEESPNINTKLEEVTAIDEAELISEKSTNNFVTDNPVSENYLTLSSALTSSEVDNSHTLLHSLENDENTVETDVTSSNSESSVAKNPITVQQEIDPDFSHNVEKATQNLTPQPPLLADNGEILQPLSFQDQGFLDSMKSQEIDSSVTSESPDIVPVQLIPTSAVIEDTPSLFSNPDSDEQLVTSESQSAMVVHVSDISANVTSLQRDSNIQNPGSEFTESQPILAAPEIAEAPTISATSPEITETPTVTAISPEIDEALVVSATSPEIAETPTISAISPEIDEALVVSTNSPEITEIPTISAISPEIDEALVISASSPEITEIPTISAISPEIDEALVVSTNSPEIAETPIVTATSPEIDEALVVSASSPEIVQKTSIFREIIDNEKTVESENPEISTFADTWDNPDILDNPTSPQDEVSTAPKVEQNAIAENLPAPKGYATGGHVTDSRVENRQQIAPSDTVPAMLTPGEFVINTRDAQKNLPLLHHINTGGTPHDIILPSLQTPNPIEPEATISPETPTKVDSFSDTSLQLKSAETDSPEISNSLIPSSFGLNSNKQKLSILNYPQLHTLQNETTDVGESSPQYSSPPLIFRKANSSTHTPSQWSDTPSQWSSVEDLLNGNNDDFTSFNFNDGESNSQNYEFSHVSESPQVFAKHLPSPRGFANGGEVTPPDISREIQPITETIESVSSSSLGDEKDDTADLEALAREIYHRLRQRIEIERERHGGYSGRLPW
>NZ_CP046703|6595657:6628147|6627118_6628147_+|WP_114082334.1|tail|DBSCAN-SWA
MVQSRSSPAVSIQLTPMQIPEALPVAGLGFANADMDVAGRTLLLHPGHPSEMIVQVQNLEQRPLRVSLSVEGNFPSQWCQIGTEGSEIPPRGQMDAVLYFSIPDTFFEDQEAISPGTKDKLTLNFRSLVTLHIDPGTDNEQIERSEYFDLYIRPYTAYMEFLPILYREVDFIGRFMKIFEQAFQPIVDSYNVMWANLDPLTAPQALLPFMAHWVAWQVDSVWDLQQQRRLIRRAVELYRWRGTRKGLRLYLHLYTGLPLDEHLPNEADKHISITEPFGPSFIIGDAQLGNAVLAGGQPYHFIVRLRSNISSGIINEQLIQRIIEQEKPAFCTYELSIENPTH
>NZ_CP046703|6595657:6628147|6605288_6605636_-|WP_114082350.1|DBSCAN-SWA
MFPTEFEFTLPKGYLDSEGNLHRKGVMRLSTAIDEIAPLRDPRVKANPVYATIIILSRVITHLGALSEVTPAIVENFFAQDLNYLQDFYRRINGLEGETSIPEDTVNSPEAVLHN
>NZ_CP046703|6595657:6628147|6602615_6604604_-|WP_114082351.1|DBSCAN-SWA
MKVKVSYSPNLSEVNEVDLTTETPTRGEWLIGRSPDSDLVLDSPDISRVHAKFFVKAGNYYFSDLGSRNGSIFNGKQAEKDRPYSLSDGDIIRIADYVLILEAVAPAYEQPETVFRIIDPSLFSRPRSPESVSAANVVNPSPELVSEVSAPITPEVETPSPEVSETSEVVANQPDDVIPVVEIIAPENIIQSPEAVSEVPHNVHDEIGDLQALVAPEVSADVEEVKIPEVSENGEEVSFTVADDAIAAPENIIETSEEEITFPEATDDEVTDFQTALATESTFVQRRDIEATSPEDAELEAALEAEVTFVQPRDIFHQVPETTSPEDAELEAALEAEVTFVQPRDIFGEVSDEESTVLEVTHNENQVVDLDTPVAEEVSLEFGEFVNEVTEEEEIQPQETLSQPTQDINDELADLDILFTTEDSTNINEVEPSFAVDETGGEVSEALTEPDNIVAEVSSNQYIDLNNTTTEEASVNVDDVVLVSEVSELADIQSLETTESEVPESISQTIEEVPEVEAAQFDETPEEINVSEPPQVIIERNIVLIAHESKKSELAEFVSQHQEFFSQSFTITWPSVGEVLHQQAGITISQQTPAPISGGYQTIASLVGAGEILAVIFLRDLLQPQPGQANEEALLRLCTINQVLLATNLPTAEAIVHYLKHI

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_159402613.1|6595657_6596880_-|transposase	ISAzo13 family transposase	NA	NA	NA	NA
WP_114082355.1|6597062_6597728_+	fimbrial protein	NA	NA	NA	NA
WP_114082354.1|6597752_6598526_+	hypothetical protein	NA	NA	NA	NA
WP_114082353.1|6598601_6599330_-	hypothetical protein	NA	NA	NA	NA
WP_147262512.1|6599702_6599921_-	hypothetical protein	NA	NA	NA	NA
WP_114082352.1|6600276_6602457_-	CHASE2 domain-containing protein	A0A2R8FDX7	Brazilian_cedratvirus	2.8e-05	29.4
WP_114082351.1|6602615_6604604_-	FHA domain-containing protein	NA	NA	NA	NA
WP_114082360.1|6604746_6605130_-|tail	phage tail assembly protein	NA	NA	NA	NA
WP_114082350.1|6605288_6605636_-	hypothetical protein	NA	NA	NA	NA
WP_041565926.1|6605647_6606142_-|tail	phage tail protein	NA	NA	NA	NA
WP_114082349.1|6606164_6606620_-|tail	phage tail protein	NA	NA	NA	NA
WP_114082348.1|6606843_6608505_-|tail	phage tail sheath family protein	H6WFT7	Cyanophage	1.2e-19	33.7
WP_114082347.1|6608535_6609375_-	DUF4255 domain-containing protein	NA	NA	NA	NA
WP_159402592.1|6609449_6609611_+	hypothetical protein	NA	NA	NA	NA
WP_114082346.1|6610062_6611184_+	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_114082345.1|6611207_6611888_+	response regulator transcription factor	NA	NA	NA	NA
WP_114082344.1|6611931_6614070_+	serine/threonine protein kinase	NA	NA	NA	NA
WP_114082343.1|6614041_6614689_+	FHA domain-containing protein	NA	NA	NA	NA
WP_167756026.1|6614864_6616151_-	DUF4157 domain-containing protein	NA	NA	NA	NA
WP_114082342.1|6616700_6616940_+	hypothetical protein	NA	NA	NA	NA
WP_114082341.1|6616939_6617464_+|tail	phage tail protein	NA	NA	NA	NA
WP_114082340.1|6617487_6620826_+	hypothetical protein	A0A1L2BX61	Bacteriophage	4.4e-10	34.3
WP_114082339.1|6620864_6621422_+	hypothetical protein	NA	NA	NA	NA
WP_114082338.1|6621502_6623236_+	VgrG-related protein	NA	NA	NA	NA
WP_114082337.1|6623354_6623852_+	hypothetical protein	NA	NA	NA	NA
WP_114082336.1|6624209_6624623_+	GPW/gp25 family protein	A0A088FV58	Escherichia_phage	3.3e-08	43.2
WP_114082335.1|6624844_6627043_+|plate	putative baseplate assembly protein	NA	NA	NA	NA
WP_114082334.1|6627118_6628147_+|tail	phage tail protein	NA	NA	NA	NA