CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP047813	Staphylococcus aureus strain UP_1500 chromosome, complete genome	13 crisprs	csa3,cas3,DinG,DEDDh,WYL	9	5	11	1
NZ_CP047814	Staphylococcus aureus strain UP_1500 plasmid unnamed, complete sequence	0 crisprs	NA	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP047813_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047813_1

224845-224923

Orphan

Consensus_repeat	Method
TGTTGGGGCCCCGCCAACTTGCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP047813_1

>merge|NZ_CP047813|1|224845-224923|CRISPRCasFinder
TGTTGGGGCCCCGCCAACTTGCACATTATTGAAAGCTGACTATTGGCCAGCTTCTATGTTGGGGCCCCGCCAACTTGCA

>NZ_CP047813|1|1|224845-224923|CRISPRCasFinder
TGTTGGGGCCCCGCCAACTTGCA	CATTATTGAAAGCTGACTATTGGCCAGCTTCTA
TGTTGGGGCCCCGCCAACTTGCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047813.1\|WP_160186684.1\|210393_212808_+\|leucine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234743
NZ_CP047813.1\|WP_001217124.1\|223476_224172_+\|rRNA-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|224108
NZ_CP047813.1\|WP_001048368.1\|233768_234365_+\|DUF4479-domain-containing-protein	unknown	unknown	gnl\|CDD\|234804
NZ_CP047813.1\|WP_000836465.1\|212829_213141_+\|rhodanese-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|238089
NZ_CP047813.1\|WP_000434765.1\|228035_228827_+\|phosphotransferase-family-protein	unknown	unknown	gnl\|CDD\|223584
NZ_CP047813.1\|WP_000163829.1\|230932_231244_-\|peptidase	unknown	unknown	gnl\|CDD\|227871
NZ_CP047813.1\|WP_001091387.1\|232882_233740_+\|DUF1444-domain-containing-protein	unknown	unknown	gnl\|CDD\|237463
NZ_CP047813.1\|WP_043044059.1\|207857_208811_-\|TIGR01212-family-radical-SAM-protein	unknown	unknown	gnl\|CDD\|224163
NZ_CP047813.1\|WP_001024574.1\|231330_232407_+\|M42-family-metallopeptidase	unknown	unknown	gnl\|CDD\|349906
NZ_CP047813.1\|WP_001051856.1\|224188_224611_+\|YtxH-domain-containing-protein	unknown	unknown	gnl\|CDD\|378938
NZ_CP047813.1\|WP_006190539.1\|213466_220027_+\|LPXTG-anchored-repetitive-surface-protein-SasC	unknown	unknown	gnl\|CDD\|275089
NZ_CP047813.1\|WP_000265410.1\|225224_226634_+\|Mn(2+)-dependent-dipeptidase-Sapep	unknown	unknown	gnl\|CDD\|235988
NZ_CP047813.1\|WP_000411085.1\|226637_227486_+\|D-amino-acid-transaminase	unknown	unknown	gnl\|CDD\|130191
NZ_CP047813.1\|WP_006190533.1\|228841_229486_+\|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB	unknown	unknown	gnl\|CDD\|234649
NZ_CP047813.1\|WP_000285018.1\|220143_221412_-\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|367519
NZ_CP047813.1\|WP_000004344.1\|221818_223480_+\|polysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|240529
NZ_CP047813.1\|WP_000764419.1\|207297_207861_-\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|377744
NZ_CP047813.1\|WP_001025067.1\|208920_210102_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340887
NZ_CP047813.1\|WP_001823213.1\|229965_230808_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293814
NZ_CP047813.1\|WP_000811163.1\|232471_232783_+\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245

Protein	Function_ID	Function_description	E-value
NZ_CP047813.1\|WP_160186684.1\|210393_212808_+\|leucine--tRNA-ligase	gnl\|CDD\|234743	PRK00390, leuS, leucyl-tRNA synthetase; Validated.	0
NZ_CP047813.1\|WP_001217124.1\|223476_224172_+\|rRNA-pseudouridine-synthase	gnl\|CDD\|224108	COG1187, RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis].	2.60709e-94
NZ_CP047813.1\|WP_001048368.1\|233768_234365_+\|DUF4479-domain-containing-protein	gnl\|CDD\|234804	PRK00629, pheT, phenylalanyl-tRNA synthetase subunit beta; Reviewed.	7.47641e-48
NZ_CP047813.1\|WP_000836465.1\|212829_213141_+\|rhodanese-like-domain-containing-protein	gnl\|CDD\|238089	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.	1.46882e-25
NZ_CP047813.1\|WP_000434765.1\|228035_228827_+\|phosphotransferase-family-protein	gnl\|CDD\|223584	COG0510, ycfN, Thiamine kinase and related kinases [Coenzyme transport and metabolism].	5.2385e-83
NZ_CP047813.1\|WP_000163829.1\|230932_231244_-\|peptidase	gnl\|CDD\|227871	COG5584, COG5584, Predicted small secreted protein [Function unknown].	4.0694e-45
NZ_CP047813.1\|WP_001091387.1\|232882_233740_+\|DUF1444-domain-containing-protein	gnl\|CDD\|237463	PRK13668, PRK13668, hypothetical protein; Provisional.	2.02352e-168
NZ_CP047813.1\|WP_043044059.1\|207857_208811_-\|TIGR01212-family-radical-SAM-protein	gnl\|CDD\|224163	COG1242, COG1242, Predicted Fe-S oxidoreductase [General function prediction only].	0
NZ_CP047813.1\|WP_001024574.1\|231330_232407_+\|M42-family-metallopeptidase	gnl\|CDD\|349906	cd05656, M42_Frv, M42 Peptidase, endoglucanases. Peptidase M42 family, Frv (Frv Operon Protein; Endo-1 4-Beta-Glucanase; Cellulase Protein; Endoglucanase; Endo-1 4-Beta-Glucanase Homolog; Glucanase; EC. 3.2.1.4) subfamily. Frv is a co-catalytic metallopeptidase, found in archaea and bacteria, including Pyrococcus horikoshii tetrahedral shaped phTET1 (DAPPh1; FrvX; PhDAP aminopeptidase; PhTET aminopeptidase; deblocking aminopeptidase), phTET2 (DAPPh2) and phTET3 (DAPPh3), Haloarcula marismortui TET (HmTET) as well as Bacillus subtilis YsdC. All of these exhibit aminopeptidase and deblocking activities. The HmTET is a broad substrate aminopeptidase capable of degrading large peptides. PhTET2, which shares 24% identity with HmTET, is a cobalt-activated peptidase and possibly a deblocking aminopeptidase, assembled as a 12-subunit tetrahedral dodecamer, while PhTET1 can be alternatively assembled as a tetrahedral dodecamer or as an octahedral tetracosameric structure. The active site in such a self-compartmentalized complex is located on the inside such that substrate sizes are limited, indicating function as possible peptide scavengers. PhTET2 cleaves polypeptides by a nonprocessive mechanism, preferring N-terminal hydrophobic or uncharged polar amino acids. Streptococcus pneumoniae PepA (SpPepA) also forms dodecamer with tetrahedral architecture, and exhibits selective substrate specificity to acidic amino acids with the preference to glutamic acid, with the substrate binding S1 pocket containing an Arg allows electrostatic interactions with the N-terminal acidic residue in the substrate. The YsdC gene is conserved in a number of thermophiles, archaea and pathogenic bacterial species; the closest structural homolog is Thermotoga maritima FrwX (34% identity), which is annotated as either a cellulase or an endoglucanase, and is possibly involved in polysaccharide biosynthesis or degradation.	4.15596e-153
NZ_CP047813.1\|WP_001051856.1\|224188_224611_+\|YtxH-domain-containing-protein	gnl\|CDD\|378938	pfam12732, YtxH, YtxH-like protein. This family of proteins is found in bacteria. Proteins in this family are typically between 100 and 143 amino acids in length. The N-terminal region is the most conserved. Proteins is this family are functionally uncharacterized.	0.000451559
NZ_CP047813.1\|WP_006190539.1\|213466_220027_+\|LPXTG-anchored-repetitive-surface-protein-SasC	gnl\|CDD\|275089	TIGR04263, cell_wall_surface_anchor_family_protein, SasC/Mrp/FmtB intercellular aggregation domain. This domain, about 375 amino acids long on average, occurs only in Staphylococcus and Streptococcus. It occurs as a non-repetitive N-terminal domain of LPXTG-anchored surface proteins, including SasC, Mrp, and FmtB. This region in SasC was shown to be involved in cell aggregation and biofilm formation, which may explain the methicillin resistance seen for Mrp and FmtB.	7.35007e-121
NZ_CP047813.1\|WP_000265410.1\|225224_226634_+\|Mn(2+)-dependent-dipeptidase-Sapep	gnl\|CDD\|235988	PRK07318, PRK07318, dipeptidase PepV; Reviewed.	0
NZ_CP047813.1\|WP_000411085.1\|226637_227486_+\|D-amino-acid-transaminase	gnl\|CDD\|130191	TIGR01121, D-alanine_aminotransferase, D-amino acid aminotransferase. This enzyme is a homodimer. The pyridoxal phosphate attachment site is the Lys at position 146 of the seed alignment, in the motif Cys-Asp-Ile-Lys-Ser-Leu-Asn. Specificity is broad for various D-amino acids, and differs among members of the family; the family is designated equivalog, but with this caveat attached. [Energy metabolism, Amino acids and amines].	6.28892e-159
NZ_CP047813.1\|WP_006190533.1\|228841_229486_+\|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB	gnl\|CDD\|234649	PRK00121, trmB, tRNA (guanine-N(7)-)-methyltransferase; Reviewed.	5.21152e-87
NZ_CP047813.1\|WP_000285018.1\|220143_221412_-\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|367519	pfam03486, HI0933_like, HI0933-like protein.	0
NZ_CP047813.1\|WP_000004344.1\|221818_223480_+\|polysaccharide-biosynthesis-protein	gnl\|CDD\|240529	cd13124, MATE_SpoVB_like, Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins. The integral membrane protein SpoVB has been implicated in the biosynthesis of the peptidoglycan component of the spore cortex in Bacillus subtilis. This model represents a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	1.06974e-123
NZ_CP047813.1\|WP_000764419.1\|207297_207861_-\|methyltransferase-domain-containing-protein	gnl\|CDD\|377744	pfam06962, rRNA_methylase, Putative rRNA methylase. This family contains a number of putative rRNA methylases. Note that many family members are hypothetical proteins.	2.38341e-67
NZ_CP047813.1\|WP_001025067.1\|208920_210102_+\|MFS-transporter	gnl\|CDD\|340887	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MdtH and similar multidrug resistance (MDR) transporters from bacteria and archaea, many of which remain uncharacterized. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtH confers resistance to norfloxacin and enoxacin. MdtH-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.37773e-94
NZ_CP047813.1\|WP_001823213.1\|229965_230808_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293814	cd07728, YtnP-like_MBL-fold, Bacillus subtilis YtnP and related proteins; MBL-fold metallo hydrolase domain. Bacillus subtilis YtnP inhibits the signaling pathway required for the streptomycin production and development of aerial mycelium in Streptomyces griseus. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	1.13556e-156
NZ_CP047813.1\|WP_000811163.1\|232471_232783_+\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	2.34221e-24

>NZ_CP047813.1|WP_001051856.1|224188_224611_+|YtxH-domain-containing-protein
MAKGNLFKAILGIGGAVAAVLVTRKDSRDKLKAEYNKYKQDPQSYKDNAKDKATQLGTIANETIKEVKTNPKEYANRLKNNPKAFFEEEKSKFTEYDNKTDESIEKGKFDDEGGAAPNNNLRIVTEEDLKKNKNALSDKE
>NZ_CP047813.1|WP_001217124.1|223476_224172_+|rRNA-pseudouridine-synthase
MRIDKFLANMGVGTRNEVKQLLKKGLVNVNEQVIKSPKTHIEPENDKITVRGELIEYIENVYIMLNKPKGYISATEDHHSKTVIDLIPEYQHLNIFPVGRLDKDTEGLLLITNDGDFNHELMSPNKHVSKKYEVISANPITEDDIQAFKEGVTLSDGKVKPAILTYIDNQTSHVTIYEGKYHQVKRMFHSIQNEVLHLRRIKIADLELDSNLDSGEYRLLTENDFDKLNYK
>NZ_CP047813.1|WP_000004344.1|221818_223480_+|polysaccharide-biosynthesis-protein
MSESKEMVRGTFLITISILITKVLGVLFIIPFNYLIGGQENMAPFTYAYAPYNIAIAVATAGVPLAASKYVAKYNAIGAYKVSQKFYKSSFIVMSITGVLGFLVLYFLAPYISELTLARNVHDKNGWSVDDITWIIRIISMVVIFIPVLATWRGIFQGYKSMGPTAVSEVTEQIARVIFILIGSYLVLNVFDGSILLANGIATFAAAVGAIIGIFTLWYYWRKRKHNIDRMVESDYTDIDVSYGKMYKEIIAYSIPFVIVSLNYPLFNLVDQFTHNGALSLVGIPSQLQDIFFNMLNMSTNKIVMIPTSLSAGFAVSLIPYITKTFAEGRLHEMHHQIRTSIGVLMFITVPASIGIMALAQPLFTVFYGYDPIVLGHDPNHDGSRLLFYYAPVAILISLLSVTASMLQGIDKQKLTVYVILASVVIKLALNYPLIMLFHTPGAILSTSIALLFAIGCNFYILKKYAKFKFSYSWIHFAKIFLYSFIMMLGVELVFFLANLFLEPTKLGYLIIIILGVTVGILIYGTITIKTRLADEFLGEIPEKLRRRVRFLR
>NZ_CP047813.1|WP_000285018.1|220143_221412_-|NAD(P)/FAD-dependent-oxidoreductase
MYQTIIIGGGPSGLMAAVAASEQSSSVLLIEKKKGLGRKLKISGGGRCNVTNRLPYAEIIKNIPGNGKFLYSPFSIFDNESIIDFFESRGVKLKEEDHGRMFPVSNKAQDVVDTLVTTIERQHVTIKEEEAVSRIEVNTDQTFTVHTQNNSYESHSLVIATGGTSVPQTGSTGDGYKFAQDLGHTITELFPTEVPITSAEPFIKSNRLKGLSLKDVELSVLKKNGKKRISHQMDMLFTHFGISGPAALRCSQFVYKEQKNQKTQHISMAIDAFPELNHEQLKQHITSLLSDTPDKIIKNSLHGLIEERYLLFMLEQAGIDENTTSHHLSNQQLNDLVNMFKGFIFKVNGTLPIDKAFVTGGGVSLKEIQPKTMMSKLVPGLFLCGEVLDIHGYTGGYNITSALVTGHVAGLYAGHYSHTSME
>NZ_CP047813.1|WP_006190539.1|213466_220027_+|LPXTG-anchored-repetitive-surface-protein-SasC
MNLLKKNKYSIRKYKVGIFSTLIGTVLLLSNPNGAQALTTDNNVQSDTNQATPVNSQDKDVANNRGLANSAQNTPNQSATTNQATNQALVNHNNGSIVNQATPTSVQSSTPSAQNNNHTDGNTTATETVSNANNNDAVSNNTTLNVPNKTNENGSGGHLTLKEIQEDVRHSSDKPELVAIAEPASNRPKKRSRRAAPADPNATPADPAAAAAGNGGAPVAITAPYTPTTDPNANNAGQNAPNEVLSFDDNGIRPSTNRSVPSVTVVDNLPGFTLINGGKVGVFSHAMVRTSMFDSADAKNYQAQGNVIALGRIKGNDTNDHGDFNGIEKTLTVNPNSELIFEFNTMTTKNYQGVTNLIIKNADNDTVIAEKSVAYGPIWRLFKVPENVSHLKIQFVPKNDAITDARGIYQLRDGYKYYDFVDSIGLHSGSHVYVERRTMEPTATNNKEFTVTTSLKNNGNFGASFNTDDFVYQVQLPEGVEYVNNSLTKDFPSSNSGVDMNDFNVTYDAANRVITIKSTGGGSGNSPARLMPDKILDLKYKLRVNNVPTPRTVTFNDTLTYKTYTQDFINSPAESHTVSTNPYTIDIIMNKDALQAEVDRRIQQADYTFASLDIFNDLKRRAQTILDENRNNVPLNKRVSQADIDSLTNQMQHTLIRSVDAENAVNKKVDQMEDLVNQNDELTDEEKQAAIQVIEEHKNEIIGNIGDQTTDDGVTRIKDQGIQTLSGDTATPVVKPNAKKAIRDKATKQREIINATPDATEDEIQDALNQLATDETDAIDNVTNATTNADVETAKNNGINTIGAVVPQVTHKQAARDAINQATATKRQQINSNREATQEEKNAALNELTQATNHALEQINQATTNADVDNAKGDGLNAINPIAPVTVVKQAARDAVSHDAQQHIAEINANPDATQEERQAAIDKVNAAVTAANTNILNANTNADVEQVKTNAIQGIQAITPATKVKTDAKNAIDKSAETQHNTIFNNNDATLEEQQAAQQLLDQAVATAKQNINAADTNQEVAQAKDQGTQNIVVIQPATQVKTDARNAVNDKAREAITNINATPGATREEKQEAINRVNTLKNRALTDIGVTSTTAMVNSIRDDAVNQIGAVQPHVTKKQTATGVLNDLATAKKQEINQNTNATTEEKQVALNQVDQELATAINNINQADTNAEVDQAQQLGTKAINAIQPNIVKKPAALAQINQHYNAKLAEINATPDATNDEKNAAINTLNLDRQQAIESIKQANTNAEVDQAATVAENNIDAVQVDVVKKQAARDKITAEVAKRIEAVKQTPNATDEEKQAAVNQINQLKDQAFNQINQNQTNDQVDTTTNQALKAIDNVEAEVVIKPKAIADIEKAVKEKQQQIDNSLDSTDNEKEVASQALAKEKEKALAAIDQAQTNSQVNQAATNGVSAIKIIQPETKVKPAAREKINQKANELRAKINQDKEATAEERQVALDKINEFVNQAMTDITNNRTNQQVDDTTSQALDSIALVAPEHIVRAAARDAVKQQYEAKKQEIEQAEHATDEEKQVALNQLANNEKLALQNINQAVTNNDVKRVETNGIATLKGVQPHIVIKPEAQQAIKASAENQVESIKDTPHATVDELDEANQLISDTLKQAQQEIENTNQDAAVTDVRNQTIKAIEQIKPKVRRKRAALDSIEENNKNQLDAIRNTLDTTQDERDVAIDTLNKIVNTIKNDIAQNKTNAEVDRTETDGNDNIKVILPKVQVKPAARQSVGVKAEAQNALIDQSDLSTEEERLAAKHLVEQALNQAIDQINHADKTAQVNQDSINAQNIISKIKPATTVKATALQQIQNIATNKINLIKANNEATDEEQNAAIAQVEQALIKAKQQIASAVTNADVAYLLHDGKNEIREIEPVISRKASAREQLTTLFNDKKQAIEANIQATVEERNSILAQLQNIYDTAIGQIDQDRSNAQVDKTASLNLQTIHDLDVHPIKKPDAEKTINVDLARVTALVQNYRKVSDRNKADALKAITALKLQMDEELKTARTNADVDAVLKRFNVALSDIEAVITEKENSLLRIDNIAQQTYAKFKAIATPEQLAKIKVLIDQYVADGNRMIDEDATLNDIKQHTQFIVDEILAIKLPAEATKVSPKVIQPAPKVCTPIKKEETHESRKVEKELPNTGSEGMDLPLKEFALITGAALLARRRTKNEKES
>NZ_CP047813.1|WP_000836465.1|212829_213141_+|rhodanese-like-domain-containing-protein
MKSITTDELKNKLLESKPVQIVDVRTDEETAMGYIPNAKLIPMDTIPDNLNSFNKNEIYYIVCAGGVRSAKVVEYLEANGIDAVNVEGGMHAWGDEGLEIKSI
>NZ_CP047813.1|WP_160186684.1|210393_212808_+|leucine--tRNA-ligase
MNYNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIISRYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDREVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVIDGVSERGGHPVYRKPMKQWVLKITEYADQLLADLDDLDWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKVEVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKSGVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPIIEVIEGGNVEEAACTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQRYWGEPIPVIHWEDGTMTTVPEEELPLLLPETDEIKPSGTGESPLANIDSFVNVVDEKTGMKGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYARFWHKVLYDLGIVPTKEPFQKLFNQGMILGEGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLDRVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECYKVDEVYKPYIEGFVKMLAPIAPHIGEELWSKLGHEESITYQPWPTYDEALLVDDEVEIVVQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK
>NZ_CP047813.1|WP_001025067.1|208920_210102_+|MFS-transporter
MNIPKSVWWLVIGMALNITGSSFLWPLNTIYMKQELGKSLTVAGLVLMINSFGMVIGNLLGGSLFDKLGGYKTILIGTFTCLCSTTLLNFFHGWPWYAVWLVMLGFGGGMIIPAIYAMAGAVWPNGGRQTFNAIYLAQNIGVAVGAAMGGFVAEFSFNYIFLANLIMYVVFALVAVTQFNIEINAKVKYPTHLDITGKKNKARFISLVLICAMFAICWVAYIQWESTIASFTQSINISMAQYSVLWTINGIMILVAQPLIKPVLYLLKGNLKKQMFVGIIIFMLSFFVTSFAENFTIFVVGMIILTFGEMFVWPAVPTIANQLAPDGKQGQYQGFVNSAATVGKAFGPFLGGVLVDAFNMRMMFIGMMLLLVFALILLMVFKENNTQPKKIDA
>NZ_CP047813.1|WP_043044059.1|207857_208811_-|TIGR01212-family-radical-SAM-protein
MGNHFQYAFENKRYHTWNYHLKNKFGQKIFKVALDGGFDCPNRDGTVAHGGCTFCSAAGSGDFAGNRADSIAVQFKEIKEKMHEKWHEGKYIAYFQAFTNTHAPVEVLKEKFEPVLKEPGVVGLSIGTRPDCLPDDVVEYLADLNQRTYLWIELGLQTIHQSTSDLINRAHDMKTYYDGVAKLRKHNINVCTHIINGLPGEDYDMMMATAKEVAQMDVQGIKIHLLHLLKGTPMVKQYDKGLLTFMTQEEYTNLVVDQLEVIPPEMIVHRITGDGPIDIMVGPMWSVNKWEVLNGIDAELARRNSYQGLRYKSKVKQ
>NZ_CP047813.1|WP_000764419.1|207297_207861_-|methyltransferase-domain-containing-protein
MKLERILPFSKTLIKQHITPESIVVDATCGNGNDTLFLAEQVPEGHVYGFDIQDLALENTRDKVKDFNHVSLIKDGHENIEHHINDAHKGHIDAAIFNLGYLPKGDKSIVTKPDTTIQAINSLLSLMSIEGIIVLVIYHGHSEGQIEKHALLDYLSTLDQKHAQVLQYQFLNQRNHAPFICAIEKIS
>NZ_CP047813.1|WP_000265410.1|225224_226634_+|Mn(2+)-dependent-dipeptidase-Sapep
MWKEKVQQYEDQIINDLKGLLAIESVRDDAKASEDAPVGPGPRKALDYMYEIAHRDGFTTHDVDHIAGRIEAGKGNDVLGILCHVDVVPAGDGWDSNPFEPVVTEDAIIARGTLDDKGPTIAAYYAIKILEDMNVDWKKRIHMIIGTDEESDWKCTDRYFKTEEMPTLGFAPDAEFPCIHGEKGITTFDLVQNKLAEDQDEPDYELITFKSGERYNMVPDHAEARVLVKENMTDVIQDFEYFLEQNHLQGDSTVDSGILVLTVEGKAVHGMDPSIGVNAGLYLLKFLASLNLDNNAQAFVAFSNRYLFDSDFGEKMGMKFHTDVMGDVTTNIGVITYDNENAGLFGINLRYPEGFEFEKAMDRFANEIQQYGFEVKLGKVQPPHYVDKNDPFVQKLVTAYRNQTNDMTEPYTIGGGTYARNLDKGVAFGAMFSDSEDLMHQKNEYITKKQLFNATSIYLEAIYSLCVEE
>NZ_CP047813.1|WP_000411085.1|226637_227486_+|D-amino-acid-transaminase
MEKIFLNGEFVSPSEAKVSYNDRGYVFGDGIYEYIRVYNGKLFTVTEHYERFLRSANEIGLDLNYSVEELIELSRKLVDMNQIETGAIYIQATRGVAERNHSFPTPEVEPAIVAYTKSYDRPYDHLENGVNGVTVEDIRWLRCDIKSLNLLGNVLAKEYAVKYNAVEAIQHRGETVTEGSSSNAYAIKDGVIYTHPINNYILNGITRIVIKKIAEDYNIPFKEETFTVDFLKNADEVIVSSTSAEVTPVIKLDGEPVNDGKVGPITRQLQEGFEKYIESHSI
>NZ_CP047813.1|WP_000434765.1|228035_228827_+|phosphotransferase-family-protein
MEQFYQLGWTLDSAGGASGEAYMAEQDGQKLFLKRNSNPFIAALSAEGIVPKLVWTKRIETGEVVTAQHWKNGRELSSNEMKQTRVAHLLKKIHNSRPLLSMLKRMEMEPITPEIMLNKINASLSREVLTHHIVRKSLTYLEEHIPSLDSRFFTVVHGDVNHNNWLLSDRDELFLVDWEGAMIADPAIDIGMLLYNYVPQQQWSEWLETYGVQESLNLNKRMKWYTVIQSIGLVQWYEEQKRYKDMNTWLKFLNEVMNSNMFI
>NZ_CP047813.1|WP_006190533.1|228841_229486_+|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB
MRVRYKPWAEDYLKGHPELVDMEGQHAGKMTEWFDKTQPIHIEIGSGMGQFITTLAAQNPHINYISMEREKSIVYKVLDKVKEMGLTNLKIICNDAIELNEYFKDGEVSRIYLNFSDPWPKNRHAKRRLTYHKFLALYQQILNDEGDLHFKTDNRGLFAYSLESMSQFGMYFTKINLNLHQEDNGSNILTEYEKKFSDKGSRIYRMEAKFHSQK
>NZ_CP047813.1|WP_001823213.1|229965_230808_+|MBL-fold-metallo-hydrolase
MKIGDISIHYLNGGNTKMDGGAMFGVVPKPLWSKQYNANERNQINLPTHPILIQTAQYNLIIDAGIGNGKLSEKQLRNFGVDEESHIITDLANYNLTPKDIDYVLMTHMHFDHAAGLTDQAGHAIFENAIHVVQQDEWHEFIAPNIRSKSTYWDKNKGDYSNKLILFEKHFEPVPGIKMQHSGGHSFGHTIITIESQGDKAVHMGDIFPTTAHKNPLWVTAYDDYPMQSIREKERMIPYFIQQQYWFLFYHDENYFAVKYSDDGENIDAYILRETLVDNN
>NZ_CP047813.1|WP_000163829.1|230932_231244_-|peptidase
MTKLKYIIPTIIAVAIVIISTISIIQYINRKRYNPVKVLNEVKSYFMNVKGSYIVYEPFVHPETDKYRLVYQGGITTIKNGQNIHYDFYADAYTGEVINIVER
>NZ_CP047813.1|WP_001024574.1|231330_232407_+|M42-family-metallopeptidase
MNINKKVTLQRIQTLTELHGAPGFEEEVKNYMTQQMAPYVDEFIENRMGGFFGVKKSKNPNAKRVMIAAHMDEIGFMITNITKNGMIQFTNLGGVANDIWQGQRLVIKNRNGDKIIGVVSNIPKHFRTGSEGAPEIKDLTLDIGAQNEDEVRERGIDIGDTIVPHTPFTQLSEHRYSAKAWDNRYGCVLAIEILELLKDIELDVDLYVGANVQEEVGLRGAKASAEMIDPDVAFVVDCSPANDVKGNQPLSGELGKGTLIRIKDGTMILKPAFRDYLLKLVEAHDIEHQYYMSPGGTDGGEIHKANIGIPTAVIGVCARYIHSTDSVFDIRDYFAARSLLSEAICNLDNNQIETLQYK
>NZ_CP047813.1|WP_000811163.1|232471_232783_+|thioredoxin-family-protein
MKQLESEQQFESLKQGATVFEFTAGWCPDCRVIEPDLPELEARYPMFDFVSVDRDKFMDICIENGIMGIPSFLVYKNGELLGSYIGKERKSIEQIDAFLAQYV
>NZ_CP047813.1|WP_001091387.1|232882_233740_+|DUF1444-domain-containing-protein
MNTFQMRDKLKERLSHLDVDFKFNREEETLRIYRTDNNKGITIKLNAIVAKYEDKKEKIVDEIVYYVDEAIAQMADKTLESISSSQIMPVIRATSFDKKTKQGVPFIYDEHTAETAVYYAVDLGKSYRLIDESMLEDLKLTEQQIREMSLFNVRKLSNSYTTDEVKGNIFYFINSNDGYDASRILNTAFLNEIEAQCQGEMLVAVPHQDVLIIADIRNKTGYDVMAHLTMEFFTKGLVPITSLSFGYKQGHLEPIFILGKNNKQKRDPNVIQRLEANRRKFNKDK
>NZ_CP047813.1|WP_001048368.1|233768_234365_+|DUF4479-domain-containing-protein
MNLFYNPKYVGDVAFLQIEPVEGELNYNKKGNVVEITNEGNVVGYNIFEISKDITIEEKGHIKLTDELVNVFQKRISEAGFDYKLNADLSPKFVVGYVETKDKHPDADKLSVLNVNVGNDTLQIVCGAPNVEAGQKVVVAKVGAVMPSGMVIKDAELRGVASSGMICSMKELNLPNAPEEKGIMVLNDSYEIGQAFFE

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Crispr_ID: NZ_CP047813_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047813_2

879098-879183

Orphan

Consensus_repeat	Method
CCAACTTGCACATTATTGTAAGCTGACTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP047813_2

>merge|NZ_CP047813|2|879098-879183|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTTCCACCAGCTTCTATGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTT

>NZ_CP047813|2|2|879098-879183|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTT	CCACCAGCTTCTATGTTGGGGCCCCG
CCAACTTGCACATTATTGTAAGCTGACTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047813.1\|WP_000765708.1\|879546_879693_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047813.1\|WP_000793607.1\|875057_876059_-\|ornithine-carbamoyltransferase	unknown	unknown	gnl\|CDD\|235269
NZ_CP047813.1\|WP_043044558.1\|877316_878042_+\|superantigen-like-protein-SSL13	unknown	unknown	gnl\|CDD\|106307
NZ_CP047813.1\|WP_043044561.1\|882656_882842_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047813.1\|WP_000398672.1\|869110_869245_-\|beta-class-phenol-soluble-modulin	unknown	unknown	gnl\|CDD\|368464
NZ_CP047813.1\|WP_043044551.1\|870587_871535_+\|TDT-family-transporter	unknown	unknown	gnl\|CDD\|187765
NZ_CP047813.1\|WP_031867544.1\|886242_886323_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047813.1\|WP_160186702.1\|874102_875035_-\|carbamate-kinase	unknown	unknown	gnl\|CDD\|237071
NZ_CP047813.1\|WP_000857483.1\|880365_881325_+\|beta-channel-forming-cytolysin	unknown	unknown	gnl\|CDD\|273388
NZ_CP047813.1\|WP_000669537.1\|883438_883789_-\|complement-inhibitor-SCIN-B	unknown	unknown	gnl\|CDD\|371594
NZ_CP047813.1\|WP_000231631.1\|881801_882035_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047813.1\|WP_043044553.1\|871840_872068_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047813.1\|WP_043044550.1\|870150_870339_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225382
NZ_CP047813.1\|WP_000739572.1\|885875_886271_+\|formyl-peptide-receptor	unknown	unknown	gnl\|CDD\|171849
NZ_CP047813.1\|WP_160186754.1\|872374_873880_-\|YfcC-family-protein	unknown	unknown	gnl\|CDD\|224207
NZ_CP047813.1\|WP_078103447.1\|879365_879590_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047813.1\|WP_000791587.1\|883942_884440_-\|fibrinogen-binding-protein	unknown	unknown	gnl\|CDD\|289007
NZ_CP047813.1\|WP_000147103.1\|868919_869054_-\|beta-class-phenol-soluble-modulin	unknown	unknown	gnl\|CDD\|368464
NZ_CP047813.1\|WP_043044557.1\|876496_877222_+\|superantigen-like-protein-SSL14	unknown	unknown	gnl\|CDD\|171855
NZ_CP047813.1\|WP_000584398.1\|884698_885205_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP047813.1\|WP_000793607.1\|875057_876059_-\|ornithine-carbamoyltransferase	gnl\|CDD\|235269	PRK04284, PRK04284, ornithine carbamoyltransferase; Provisional.	0
NZ_CP047813.1\|WP_043044558.1\|877316_878042_+\|superantigen-like-protein-SSL13	gnl\|CDD\|106307	PRK13349, PRK13349, superantigen-like protein; Reviewed.	1.91655e-148
NZ_CP047813.1\|WP_000398672.1\|869110_869245_-\|beta-class-phenol-soluble-modulin	gnl\|CDD\|368464	pfam05480, Staph_haemo, Staphylococcus haemolytic protein. This family consists of several different short Staphylococcal proteins, it contains SLUSH A, B and C proteins as well as haemolysin and gonococcal growth inhibitor. Some strains of the coagulase-negative Staphylococcus lugdunensis produce a synergistic hemolytic activity (SLUSH), phenotypically similar to the delta-hemolysin of S. aureus. Gonococcal growth inhibitor from Staphylococcus act on the cytoplasmic membrane of the gonococcal cell causing cytoplasmic leakage and, eventually, death.	6.35158e-13
NZ_CP047813.1\|WP_043044551.1\|870587_871535_+\|TDT-family-transporter	gnl\|CDD\|187765	cd09325, TDT_C4-dicarb_trans, C4-dicarboxylate transporters of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family. This subfamily contains bacterial C4-dicarboxylate transporters, which is part of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family. It includes Tellurite resistance protein tehA; the tehA gene encodes an integral membrane protein that has been shown to have efflux activity of quaternary ammonium compounds. TehA protein of Escherichia coli functions as a tellurite-resistance uptake permease.	4.97127e-84
NZ_CP047813.1\|WP_160186702.1\|874102_875035_-\|carbamate-kinase	gnl\|CDD\|237071	PRK12353, PRK12353, putative amino acid kinase; Reviewed.	0
NZ_CP047813.1\|WP_000669537.1\|883438_883789_-\|complement-inhibitor-SCIN-B	gnl\|CDD\|371594	pfam11546, CompInhib_SCIN, Staphylococcal complement inhibitor SCIN. SCIN is released by Staphylococcus aureus to counteract the host immune defense. The protein binds to and inhibits C3 convertases on the bacterial surface, reducing phagocytosis and blocking downstream effector functions by C3b deposition on its surface. An 18 residue stretch 31-48 is crucial for SCIN activity.	2.0882e-48
NZ_CP047813.1\|WP_000857483.1\|880365_881325_+\|beta-channel-forming-cytolysin	gnl\|CDD\|273388	TIGR01002, synergohymenotropic_toxin, beta-channel forming cytolysin. This family of cytolytic pore-forming proteins includes alpha toxin and leukocidin F and S subunits from Staphylococcus aureus, hemolysin II of Bacillus cereus, and related toxins. [Cellular processes, Toxin production and resistance].	4.27434e-141
NZ_CP047813.1\|WP_043044550.1\|870150_870339_-\|hypothetical-protein	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	0.00913217
NZ_CP047813.1\|WP_000739572.1\|885875_886271_+\|formyl-peptide-receptor	gnl\|CDD\|171849	PRK13033, PRK13033, formyl peptide receptor-like 1 inhibitory protein; Reviewed.	1.17946e-62
NZ_CP047813.1\|WP_160186754.1\|872374_873880_-\|YfcC-family-protein	gnl\|CDD\|224207	COG1288, COG1288, Predicted membrane protein [Function unknown].	0
NZ_CP047813.1\|WP_000791587.1\|883942_884440_-\|fibrinogen-binding-protein	gnl\|CDD\|289007	pfam12199, efb-c, Extracellular fibrinogen binding protein C terminal. This domain family is found in bacteria, and is approximately 70 amino acids in length. There is a conserved VLK sequence motif. It is the C terminal domain of bacterial extracellular fibrinogen binding protein. It contains a helical motif involved in complement regulation. This motif binds to complement and changes its conformation to a form which cannot activate downstream components of the complement cascade.	5.40265e-27
NZ_CP047813.1\|WP_000147103.1\|868919_869054_-\|beta-class-phenol-soluble-modulin	gnl\|CDD\|368464	pfam05480, Staph_haemo, Staphylococcus haemolytic protein. This family consists of several different short Staphylococcal proteins, it contains SLUSH A, B and C proteins as well as haemolysin and gonococcal growth inhibitor. Some strains of the coagulase-negative Staphylococcus lugdunensis produce a synergistic hemolytic activity (SLUSH), phenotypically similar to the delta-hemolysin of S. aureus. Gonococcal growth inhibitor from Staphylococcus act on the cytoplasmic membrane of the gonococcal cell causing cytoplasmic leakage and, eventually, death.	4.87929e-13
NZ_CP047813.1\|WP_043044557.1\|876496_877222_+\|superantigen-like-protein-SSL14	gnl\|CDD\|171855	PRK13043, PRK13043, superantigen-like protein; Reviewed.	9.48576e-161

>NZ_CP047813.1|WP_043044558.1|877316_878042_+|superantigen-like-protein-SSL13
MNNNITKKIILSTTLLLLGAASTQFPNTPINSSSEAKAYYINQNETNVNELTKYYSQKYLTFSNSTLWQKDNGTIHATLLQFSWYSHIQVYGPESWGNINQLRNKSVDIFGIKDQETIDSFALSQETFTGGVTPAATSNDKHYKLNVTYKDKAETFTGGFPVYEGNKPVLTLKELDFRIRQTLIKSKKLYNNSYNKGQIKITGADNNYTIDLSKRLPSTDANRYVKKPQNAKIEVILEKSN
>NZ_CP047813.1|WP_043044557.1|876496_877222_+|superantigen-like-protein-SSL14
MKKNIMNKLVLSTALLLLGTTSTQLPKTPISFSSEAKAYNISENETNINELIKYYTQPHFSLSGKWLWQKPNGSIHATLQTWVWYSHIQVFGSESWGNINQLRNKYVDIFGTKDEDTVEGYWTYDETFTGGVTPAATSSDKPYRLFLKYSDKKQTIIGGHEFYKGNKPVLTLKELDFRIRQTLIKNKKLYNGEFNKGQIKITADGNNYTIDLSKKLKLTDTNRYVKNPKNAQIEVILEKSN
>NZ_CP047813.1|WP_000793607.1|875057_876059_-|ornithine-carbamoyltransferase
MKNLRNRSFLTLLDFSRQEVEFLLTLSEDLKRAKYIGTEKPMLKNKNIALLFEKDSTRTRCAFEVAAHDQGANVTYLGPTGSQMGKKETTKDTARVLGGMYDGIEYRGFSQRTVETLAEYSGVPVWNGLTDEDHPTQVLADFLTAKEVLKKDYADINFTYVGDGRNNVANALMQGAAIMGMNFHLVCPKELNPTDELLNRCKNIAAENGGNILITDDIDQGVKGSDVIYTDVWVSMGEPDEVWKERLELLKPYQVNKEMMDKTGNPNVIFEHCLPSFHNADTKIGQQIFEKYGIREMEVTDEVFESKASVVFQEAENRMHTIKAVMVATLGEF
>NZ_CP047813.1|WP_160186702.1|874102_875035_-|carbamate-kinase
MAKIVVALGGNALGKSPQEQLELVKNTAKSLVGLITKGHEIVISHGNGPQVGSINLGLNYAAEHNQGPAFPFAECGAMSQAYIGYQLQESLQNELHSIGMDKQVVTLVTQVEVDENDPAFNNPSKPIGLFYNKEEAEQIQKEKGFIFVEDAGRGYRRVVPSPQPISIIELESIKTLIKNDILVIAAGGGGIPVIREQHDGFKGIDAVIDKDKTSALLGANIQCDQLIILTAIDYVYINFNTENQQPLKTTNVDELKRYIDENQFAKGSMLPKIEAAISFIENNPKGSVLITSLNELDAALEGKVGTVIKK
>NZ_CP047813.1|WP_160186754.1|872374_873880_-|YfcC-family-protein
MPGAFMILFILTVVAVIATWVIPAGAYSKLSYEPSSQELKIVNPHNQVKKVPGTQQELDKMGVKIKIEQFKSGAINKPVSIPNTYERLKQHPAGPEQITSSMVEGTIEAVDIMVFILVLGGLIGVVQASGSFESGLLALTKKTKGHEFMLIVFVSILMIIGGTLCGIEEEAVAFYPILVPIFIALGYDSIVSVGAIFLASSVGSTFSTINPFSVVIASNAAGTTFTDGLYWRIGACIVGAIFVISYLYWYCKKIKKDPKASYSYEDKDAFEQQWSVLKDDDSAHFTLRKKIILTLFVLPFPIMVWGVMTQGWWFPVMASAFLIFIIIIMFIAGTGKSGLGEKGTVDAFVNGASSLVGVSLIIGLARGINLVLNEGMISDTILHFSSSLVQHMSGPLFIIVLLFIFFCLGFIVPSSSGLAVLSMPIFAPLADTVGIPRFVIVTTYQFGQYAMLFLAPTGLVMATLQMLNMRYSHWFRFVWPVVAFVLIFGGGLLITQVLIYS
>NZ_CP047813.1|WP_043044553.1|871840_872068_-|hypothetical-protein
MTHLTKVLDTLTGICVVLLFSKYFVAYANMVFDWKLRCYLLENIPHLPIILFILMFIFGVPSEMIKDRQRKNNGV
>NZ_CP047813.1|WP_043044551.1|870587_871535_+|TDT-family-transporter
MRLQKAPLVTSGLVLGLLGLGNLLKDLSLTLNAVCGIFAFLIWIHLLCTMIKYFNNVKEQLNSPLVSSVFTTFFMSGFLGTTYLNTFFSNITFINSLITPIWILCLVGIMTHMIIFSIKYLKDFSLENVYPSWTVLFIGIAIAGLTAPVSGYFFIGQLTVIYGFVATCIVLPIVFKRLKAFPLQTSIKPNTSTICAPFSLVAAAYVIAFPKANAFIVIIFLLLAQIFYFYIIIQLPKLLKEPFSPVFSAFTFPLVISATALKNSLPVLMFPDIWKGLLFIEVLLATVIVLRVFIGYLRFFLKKENQDKFLRNASQ
>NZ_CP047813.1|WP_043044550.1|870150_870339_-|hypothetical-protein
MRNQIQKLLDSDLSSLHISKQTGVPQSTIHRMRKNERSLDNMSLKNAELLYKFANSIFSNKN
>NZ_CP047813.1|WP_000398672.1|869110_869245_-|beta-class-phenol-soluble-modulin
MEGLFNAIKDTVTAAINNDGAKLGTSIVSIVENGVGLLGKLFGF
>NZ_CP047813.1|WP_000147103.1|868919_869054_-|beta-class-phenol-soluble-modulin
MTGLAEAIANTVQAAQQHDSVKLGTSIVDIVANGVGLLGKLFGF
>NZ_CP047813.1|WP_078103447.1|879365_879590_-|hypothetical-protein
MLIQERGLKMTELNNIINSLQSLFESESGYKISKNSGVPYQTVQDLRNGKTKLEDARFRTIIKLYSYYVLLKEH
>NZ_CP047813.1|WP_000765708.1|879546_879693_-|hypothetical-protein
MKLFYIVFLIIIWLNIFLGNEIIHTLTVLITTLYIVNSRKGIKNDRVE
>NZ_CP047813.1|WP_000857483.1|880365_881325_+|beta-channel-forming-cytolysin
MKTRIVSSVTTTLLLGSILMNPVANAADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAADNFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWIDRSSERYKIDWEKEEMTN
>NZ_CP047813.1|WP_000231631.1|881801_882035_+|hypothetical-protein
MVFNDWEINVVYSGEHEVVANEKSLFVIDEFYDVAIAIYYLDGKLKVAHVNYGSDFTIDVANKVFELNIQNPNVDEH
>NZ_CP047813.1|WP_043044561.1|882656_882842_+|hypothetical-protein
MNKHINKKATKLLEDYKKVQQRKSEETDKGCLKSVIMLIVLFFLIIFGIVACSTNVNFFFQ
>NZ_CP047813.1|WP_000669537.1|883438_883789_-|complement-inhibitor-SCIN-B
MKFKKYILTGTLALLLSSTGIATIEGNKADASSLDKYLTESQFHDKRIAEELRTLLNKSNVYALAAGSLNPYYKRTIMMNEYRAKAALKKNDFVSMADAKVALEKIYKEIDEIINR
>NZ_CP047813.1|WP_000791587.1|883942_884440_-|fibrinogen-binding-protein
MKNKLIAKSLLTLAAIGITTTTIASTADASEGYGPREKKPVSINHNIVEYNDGTFKYQSRPKFNSTPKYIKFKHDYNILEFNDGTFEYGARPQFNKPAAKTDATIKKEQKLIQAQNLVREFEKTHTVSAHRKAQKAVNLVSFEYKVKKMVLQERIDNVLKQGLVK
>NZ_CP047813.1|WP_000584398.1|884698_885205_-|hypothetical-protein
MIIKILTILLLLCILSYLVTNRKKPFLFLKTLFMGVVFIFIGYISLAISAVIIYGIIQFITIDFGSFFLMGIILILISSIFQLFIVRLLFRKKNVDLTEVVVLEHLIQWFLVYFAIYQAVNEKMDINDINIDNFQSVFFDVSNLNLVILPTLIISWVTIFNYRMRSYK
>NZ_CP047813.1|WP_000739572.1|885875_886271_+|formyl-peptide-receptor
MKKNITKVIIASTVIATGLLTHSNDAKAFFSYEWKGLEIAKKLADDEKKDEERADRLIKDAEKERTYTGKTVEDLYVIAKKLGKGNTIAVVRIIDGGKNGYYTFDITRPLEEHRKNIKVVAKGEIDSITWY
>NZ_CP047813.1|WP_031867544.1|886242_886323_+|hypothetical-protein
MKSIRLLGIKKHTELNSCTPNVRKQC

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Crispr_ID: NZ_CP047813_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047813_3

998513-998625

Orphan

Consensus_repeat	Method
AACCCTGACAACCCTAATAATCC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP047813_3

>merge|NZ_CP047813|3|998513-998625|CRISPRCasFinder
AACGATGACCAACCTAATAATCCTGATAACCCTAACAACCCTGACAACCCTAATAATCCTGATAACCCTAACAACCCAGATGAACCAAATAACCCTGACAACCCTGATAATCC

>NZ_CP047813|3|3|998513-998625|CRISPRCasFinder
AACGATGACCAACCTAATAATCC	TGATAACCCTAACAACCCTGAC
AACCCTAATAATCCTGATAACCC	TAACAACCCAGATGAACCAAAT
AACCCTGACAACCCTGATAATCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047813.1\|WP_000620949.1\|1006336_1006888_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP047813.1\|WP_000104254.1\|985200_985491_+\|cytochrome-aa3-quinol-oxidase-subunit-IV	unknown	unknown	gnl\|CDD\|225667
NZ_CP047813.1\|WP_043044604.1\|995977_997132_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|236075
NZ_CP047813.1\|WP_000017736.1\|984598_985204_+\|cytochrome-aa3-quinol-oxidase-subunit-III	unknown	unknown	gnl\|CDD\|131943
NZ_CP047813.1\|WP_070005430.1\|990223_993994_+\|mannosyl-glycoprotein-endo-beta-N-acetylglucosamidase	unknown	unknown	gnl\|CDD\|226656
NZ_CP047813.1\|WP_000671245.1\|986027_987221_-\|teichoic-acid-D-Ala-esterase-FmtA	unknown	unknown	gnl\|CDD\|365903
NZ_CP047813.1\|WP_000284457.1\|999971_1000301_+\|staphostatin-B	unknown	unknown	gnl\|CDD\|370248
NZ_CP047813.1\|WP_000184947.1\|1000539_1001361_-\|1,4-dihydroxy-2-naphthoyl-CoA-synthase	unknown	unknown	gnl\|CDD\|180958
NZ_CP047813.1\|WP_000278015.1\|994199_994619_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_CP047813.1\|WP_001031979.1\|987671_988889_+\|polyisoprenyl-teichoic-acid--peptidoglycan-teichoic-acid-transferase	unknown	unknown	gnl\|CDD\|224235
NZ_CP047813.1\|WP_000526687.1\|1002143_1003817_-\|2-succinyl-5-enolpyruvyl-6-hydroxy-3--cyclohexene-1-carboxylic-acid-synthase	unknown	unknown	gnl\|CDD\|224087
NZ_CP047813.1\|WP_072399156.1\|1003803_1005015_-\|isochorismate-synthase	unknown	unknown	gnl\|CDD\|273127
NZ_CP047813.1\|WP_000491985.1\|989561_989996_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|225064
NZ_CP047813.1\|WP_000150199.1\|1001353_1002157_-\|2-succinyl-6-hydroxy-2,-4-cyclohexadiene-1-carboxylate-synthase	unknown	unknown	gnl\|CDD\|274729
NZ_CP047813.1\|WP_001791731.1\|1005091_1005196_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047813.1\|WP_000070966.1\|1005346_1006285_+\|1,4-dihydroxy-2-naphthoate-polyprenyltransferase	unknown	unknown	gnl\|CDD\|235695
NZ_CP047813.1\|WP_043044609.1\|998752_999934_+\|cysteine-protease-staphopain-B	unknown	unknown	gnl\|CDD\|368490
NZ_CP047813.1\|WP_000088431.1\|988936_989407_+\|DUF2538-family-protein	unknown	unknown	gnl\|CDD\|287742
NZ_CP047813.1\|WP_000202434.1\|994771_995782_+\|acyltransferase-family-protein	unknown	unknown	gnl\|CDD\|226122
NZ_CP047813.1\|WP_001788574.1\|1006977_1007268_+\|TM2-domain-containing-protein	unknown	unknown	gnl\|CDD\|225196

Protein	Function_ID	Function_description	E-value
NZ_CP047813.1\|WP_000104254.1\|985200_985491_+\|cytochrome-aa3-quinol-oxidase-subunit-IV	gnl\|CDD\|225667	COG3125, CyoD, Heme/copper-type cytochrome/quinol oxidase, subunit 4 [Energy production and conversion].	1.35708e-26
NZ_CP047813.1\|WP_043044604.1\|995977_997132_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|236075	PRK07683, PRK07683, aminotransferase A; Validated.	1.19435e-171
NZ_CP047813.1\|WP_000017736.1\|984598_985204_+\|cytochrome-aa3-quinol-oxidase-subunit-III	gnl\|CDD\|131943	TIGR02897, AA3-600_quinol_oxidase_subunit_III, cytochrome aa3 quinol oxidase, subunit III. This family (QoxC) encodes subunit III of the aa3-type quinone oxidase, one of several bacterial terminal oxidases. This complex couples oxidation of reduced quinones with the reduction of molecular oxygen to water and the pumping of protons to form a proton gradient utilized for ATP production. aa3-type oxidases contain two heme a cofactors as well as copper atoms in the active site. [Energy metabolism, Electron transport].	2.41545e-111
NZ_CP047813.1\|WP_070005430.1\|990223_993994_+\|mannosyl-glycoprotein-endo-beta-N-acetylglucosamidase	gnl\|CDD\|226656	COG4193, LytD, Beta- N-acetylglucosaminidase [Carbohydrate transport and metabolism].	2.42965e-84
NZ_CP047813.1\|WP_000671245.1\|986027_987221_-\|teichoic-acid-D-Ala-esterase-FmtA	gnl\|CDD\|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	3.32794e-60
NZ_CP047813.1\|WP_000284457.1\|999971_1000301_+\|staphostatin-B	gnl\|CDD\|370248	pfam09023, Staphostatin_B, Staphostatin B. Staphostatin B inhibits the cysteine protease Staphopain B, produced by Staphylococcus aureus, by blocking the active site of the enzyme. The domain adopts an eight-stranded mixed beta-barrel structure, with a deviation from the up-down topology of canonical beta-barrels in the amino-terminal part of the molecule.	3.73097e-61
NZ_CP047813.1\|WP_000184947.1\|1000539_1001361_-\|1,4-dihydroxy-2-naphthoyl-CoA-synthase	gnl\|CDD\|180958	PRK07396, PRK07396, dihydroxynaphthoic acid synthetase; Validated.	0
NZ_CP047813.1\|WP_000278015.1\|994199_994619_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.32571e-19
NZ_CP047813.1\|WP_001031979.1\|987671_988889_+\|polyisoprenyl-teichoic-acid--peptidoglycan-teichoic-acid-transferase	gnl\|CDD\|224235	COG1316, LytR, Transcriptional regulator [Transcription].	3.10092e-79
NZ_CP047813.1\|WP_000526687.1\|1002143_1003817_-\|2-succinyl-5-enolpyruvyl-6-hydroxy-3--cyclohexene-1-carboxylic-acid-synthase	gnl\|CDD\|224087	COG1165, MenD, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase [Coenzyme metabolism].	0
NZ_CP047813.1\|WP_072399156.1\|1003803_1005015_-\|isochorismate-synthase	gnl\|CDD\|273127	TIGR00543, Salicylate_biosynthesis_isochorismate_synthase, isochorismate synthases. This enzyme interconverts chorismate and isochorismate. In E. coli, different loci encode isochorismate synthases for the pathways of menaquinone biosynthesis and enterobactin biosynthesis (via salicilate) and fail to complement each other. Among isochorismate synthases, the N-terminal domain is poorly conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone].	2.99935e-164
NZ_CP047813.1\|WP_000491985.1\|989561_989996_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|225064	COG2153, ElaA, Predicted acyltransferase [General function prediction only].	1.32597e-23
NZ_CP047813.1\|WP_000150199.1\|1001353_1002157_-\|2-succinyl-6-hydroxy-2,-4-cyclohexadiene-1-carboxylate-synthase	gnl\|CDD\|274729	TIGR03695, menH_SHCHC, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase. This protein catalyzes the formation of SHCHC, or (1 R,6 R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate, by elmination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Note that SHCHC synthase activity previously was attributed to MenD, which in fact is SEPHCHC synthase. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone].	2.92666e-123
NZ_CP047813.1\|WP_000620949.1\|1006336_1006888_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	6.44645e-08
NZ_CP047813.1\|WP_000070966.1\|1005346_1006285_+\|1,4-dihydroxy-2-naphthoate-polyprenyltransferase	gnl\|CDD\|235695	PRK06080, PRK06080, 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated.	3.61649e-125
NZ_CP047813.1\|WP_043044609.1\|998752_999934_+\|cysteine-protease-staphopain-B	gnl\|CDD\|368490	pfam05543, Peptidase_C47, Staphopain peptidase C47. Staphopains are one of four major families of proteinases secreted by the Gram-positive Staphylococcus aureus. These staphylococcal cysteine proteases are secreted as preproenzymes that are proteolytically cleaved to generate the mature enzyme.	8.21201e-108
NZ_CP047813.1\|WP_000088431.1\|988936_989407_+\|DUF2538-family-protein	gnl\|CDD\|287742	pfam10804, DUF2538, Protein of unknown function (DUF2538). This family of proteins has no known function.	4.64019e-106
NZ_CP047813.1\|WP_000202434.1\|994771_995782_+\|acyltransferase-family-protein	gnl\|CDD\|226122	COG3594, NolL, Fucose 4-O-acetylase and related acetyltransferases [Carbohydrate transport and metabolism].	4.87793e-78
NZ_CP047813.1\|WP_001788574.1\|1006977_1007268_+\|TM2-domain-containing-protein	gnl\|CDD\|225196	COG2314, XynA, Predicted membrane protein [Function unknown].	4.16855e-10

>NZ_CP047813.1|WP_043044604.1|995977_997132_+|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MKLSLNSNSKYLRAPSIRQFSNRMNNLDDCVNLTIGQPDFPMPDVVKKAYIDAINNDKTSYSHNKGLLETREAISQYFKNRYHFSYDPEEIIVTNGASEAIDTTLRSIIEPGDEIIIPGPIYAGYIPLIEVLGGKPIYIDTTTTQFKITPDALESHISPKTKAVLLNYPTNPTGVVLKRNEVLNIVNVLKKYPIFIISDEIYAENTFSGKHVSFAEFEDIRNQLILIGGLSKSHSATGIRIGFLLGPQYLIDKLTFMHAYNCICANVPAQIACITALNEGLEAPKYMNEAYVERRNYLVSELTKLGFEITAQPEGAFYIFPSIKHITDDDFEFCVDLLESTHLAIVPGSSFTEFGKGFVRISYAYEMDVLKEGMKRLAKYLNTK
>NZ_CP047813.1|WP_000202434.1|994771_995782_+|acyltransferase-family-protein
MTSLKERDYFFDNARAILILLVVFGHMLQPYTSGDKYLSALYLVIYSFHMPTFLFISGYFAKNIDKPYYLEKISKRLIVPYMIFFAFFSIYYFLTGKSDELQLDPFNPVFALWFLITLFFFHVILVIVRRFNPYKVLSVSIIISIGAGFSDNIDSYLSISRTIVFFPIFYLGYIFTKKHTAIFKNKKLIPVSIITFILFFIIYVIHPINADWLLGSSPYTSLENEGQSVFSPFKRLILYGIILIAMTAFLNLMSTKKKLYTYIGSRTLYVYLLHGLIIGIVRGFEWYPFDNPISLMTYLYLISISVIIVYVLSTNFVCKWTNPIINLQRPSQFKDS
>NZ_CP047813.1|WP_000278015.1|994199_994619_-|MarR-family-transcriptional-regulator
MYKQLEKLITLTNNDLNLVNRRFGQRTDITSEQLELLRILFNYDRLSQYDLTMKISREQSIVSRWIKKLVLKGYITSQQSSEDLRCKELILTDQARTLISQINNARCELIEARCQCLSEVELDNLNQLLDKLNQRRISL
>NZ_CP047813.1|WP_070005430.1|990223_993994_+|mannosyl-glycoprotein-endo-beta-N-acetylglucosamidase
MAKKFNYKLPSMVALTLVGSAVTAHQVQAAETTQDQTTNKNVLDSNKVKATTEQAKAEVKNPTQNISGTQVYQDPAIVQPKTANNKTGNAQVSQKVDTAQVNGDTRANQSATTNNTQPVAKSTSTTTPKTNTNVTNAGYSLVDDEDDNSENQINPELIKSAAKPAALETQYKAAAPKAATSSAPKAKTEATPKVTTFSASAQPRSVAATPKTSLPKYKPQVNSSINDYIRKNNLKAPKIEEDYTSYFPKYAYRNGVGRPEGIVVHDTANDRSTINGEISYMKNNYQNAFVHAFVDGDRIIETAPTDYLSWGVGAVGNPRFINVEIVHTHDYASFARSMNNYADYAATQLQYYGLKPDSAEYDGNGTVWTHYAVSKYLGGTDHADPHGYLRSHNYSYDQLYDLINEKYLIKMGKVAPWGTQSTTTPTTPSKPTTPSKPSTGKLTVAANNGVAQIKPTNSGLYTTVYDKTGKATNEVQKTFAVSKTATLGNQKFYLVQDYNSGNKFGWVKEGDVVYNTAKSPVNVNQSYSIKPGTKLYTVPWGTSKQVAGSVSGSGNQTFKASKQQQIDKSIYLYGSVNGKSGWVSKAYLVDTAKPTPTPIPKPSTPTTNNKLTVSSLNGVAQINAKNNGLFTTVYDKTGKPTKEVQKTFAVTKEASLGGNKFYLVKDYNSPTLIGWVKQGDVIYNNAKSPVNVMQTYTVKPGTKLYSVPWGTYKQEAGAVSGTGNQTFKATKQQQIDKSIYLFGTVNGKSGWVSKAYLAVPAAPKKAVAQPKTAVKAYTVTKPQTTQTVSKIAQVKPNNTGIRASVYEKTAKNAAKYADRTFYVTKERAHGNETYVLLNNTSHNIPLGWFNVKDLNVQNLGKEVKTTQKYTVNKSNNGLSMVPWGTKNQVILTGNNIAQGTFNATKQVSVGKDVYLYGTINNRTGWVNAKDLTAPTAVKPTTSAAKDYNYTYVIKNGNGYYYVTPNSDTAKYSLKAFNEQPFAVVKEQVINGQTWYYGKLSNGKLAWIKSTDLAKELIKYNQTGMTLNQVAQIQAGLQYKPQVQRVPGKWTDANFNDVKHAMDTKRLAQDPALKYQFLRLDQPQNISIDKINQFLKGKGVLENQGAAFNKAAQMYGINEVYLISHALLETGNGTSQLAKGADVVNNKVVTNSNTKYHNVFGIAAYDNDPLREGIKYAKQAGWDTVSKAIVGGAKFIGNSYVKAGQNTLYKMRWNPAHPGTHQYATDVDWANINAKIIKGYYDKIGEVGKYFDIPQYK
>NZ_CP047813.1|WP_000491985.1|989561_989996_+|GNAT-family-N-acetyltransferase
MFSKVNNQKMLEDCFYIRKKVFVEEQGVPEESEIDEYESESIHLIGYDNGQPVATARIRPINETTVKIERVAVMKSHRGQGMGRILMQAVESLAKDEGFYVATMNAQCHAIPFYESLNFKMRGNIFLEEGIEHIEMTKKLTSLN
>NZ_CP047813.1|WP_000088431.1|988936_989407_+|DUF2538-family-protein
MSRKTYEKIANINGMFNMLEQQIIHSQDMAHFRSEFFYVNHEHRENYEALLIYYKNSIDNPIVDGACYILALPEIFNSVDVFESELPFSWVYDENGITETMKSLSIPLQYLVAAALEVTDVNIFKPSGFTMGMNNWNIAQMRIFWQYTAIIRKEAL
>NZ_CP047813.1|WP_001031979.1|987671_988889_+|polyisoprenyl-teichoic-acid--peptidoglycan-teichoic-acid-transferase
MNKFLKYFLILLALVLIVVPIVFATLLFKTSQDAFESSQDSKNANRQSNLRDNKVNPEEQPISILFLGIDDNDGRRKKGQDAEHSRSDAMILTTFNQSKHQIRMLSIPRDTISYIPKVGYYDKITHAHAYGGPIAAMDSVEATMNVPVDYYVRVNMKAFVEAVNELGGIYYDVPYDLNEPNTDDTGKIKIKKGYQKLNGDEALAVARTRHHDSDLKRGQRQMELIKILFQKAQEVDSIDKLDNVIQIVGKNAKHNLTNSEIKALAKMYLTNDVEIKTAQLKGKDDMLNGIYYYHPSVESIQKYANLLRKDLELSPINDKNDFLDQRVINHYGSLIPLTPLDSSLLRKEQNDTTDKDKTSYENNDSTNNSDSSNQQQPATDQNLNQNQGGTQQAPQASNNQNGVVN
>NZ_CP047813.1|WP_000671245.1|986027_987221_-|teichoic-acid-D-Ala-esterase-FmtA
MKFNKVKLVIHACVLLFIIISIALIFHRLQTKTHSIDPIHKETKLSDNEKYLVDRNKEKVAPSKLKEVYNSKDPKYKKIDKYLQSSLFNGSVAIYENGKLKMSKGYGYQDFEKGIKNTPNTMFLIGSAQKFSTGLLLKQLEEEHKININDPVSKYLPWFKTSKPIPLKDLMLHQSGLYKYKSSKDYKNLDQAVKAIQKRGIDPKKYKKHMYNDGNYLVLAKVIEEVTGKSYAENYYTKIGDPLKLQHTAFYDEQPFKKYLAKGYAYNSTGLSFLRPNILDQYYGAGNLYMTPTDMGKLITQIQQYKLFSPKITNPLLHEFGTKQYPDEYRYGFYAKPTLNRLNGGFFGQVFTVYYNDKYVVVLALNVKGNNEVRIKHIYNDILKQNKPYNTKGVIVQ
>NZ_CP047813.1|WP_000104254.1|985200_985491_+|cytochrome-aa3-quinol-oxidase-subunit-IV
MSTIMKHTVGFIASIVLTLLAVYVTLYTSLTFHAKLTIIFGFAFVQAGLQLLMFMHLTEGKDGRLQTFKVIFALVITLCFVVGTYWVMQGGHSSHL
>NZ_CP047813.1|WP_000017736.1|984598_985204_+|cytochrome-aa3-quinol-oxidase-subunit-III
MSHDTNTIDSRTHEGELNKLGFWIFITAEFALFGTLFATLLTLQHGGDYAGKMTTELFELPLVLIMTFALLFSSYTCGIAIYYMRQEKQKLMMFWMIITLLLGLVFVGFEIYEFAHYASEGVNPTIGSYWSSFFILLGTHGCHVSLGIVWAICLLIQIQRRGLDKYNAPKLFIVSLYWHFLDVVWVFIFTAVYMIGMVYSG
>NZ_CP047813.1|WP_043044609.1|998752_999934_+|cysteine-protease-staphopain-B
MNSSCKSRVFNIISIIMVSMLILSLGAFANNNKAKADSHSKQLEINVKSDKVPQKVKDLAQQQFAGYAKALDKQSNAKTGKYELGEAFKIYKFNGEEDNSYYYPVIKDGKIVYTLTLSPKNKDDLNKSKEDMNYSVKISNFIAKDLDQIKDKNSNITVLTDEKGFYFEEDGKVRLVKATPLPGNVKEKESAKTVSTKLKQELKNTVTPTKVEENEAIQEDQVQYENTLKNFKIREQQFDNSWCAGFSMAALLNATKNTDTYNAHDIMRTLYPEVSEQDLPNCATFPNQMIEYGKSQGRDIHYQEGVPSYEQVDQLTKDNVGIMILAQSVSQNPNDPHLGHALAVVGNAKINDQEKLIYWNPWDTELSIQDADSSLLHLSFNRDYNWYGSMIGY
>NZ_CP047813.1|WP_000284457.1|999971_1000301_+|staphostatin-B
MYQLQFINLVYDTTKLTHLEQTNINLFIGNWSNHQLQKSICIRHGDDTSHNQYHILFIDTAHQRIKFSSIDNEEIIYILDYDDTQHILMQTSSKQGIGTSRPIVYERLV
>NZ_CP047813.1|WP_000184947.1|1000539_1001361_-|1,4-dihydroxy-2-naphthoyl-CoA-synthase
MTNRQWETLREYDEIKYEFYEGIAKVTINRPEVRNAFTPKTVAEMIDAFSRARDDQNVSVIVLTGEGDLAFCSGGDQKKRGHGGYVGEDQIPRLNVLDLQRLIRIIPKPVIAMVKGYAVGGGNVLNVVCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMGLVNTVVPLEKVEDETVQWCKEIMKHSPTALRFLKAAMNADTDGLAGLQQMAGDATLLYYTTDEAKEGRDAFKEKRDPDFDQFPKFP
>NZ_CP047813.1|WP_000150199.1|1001353_1002157_-|2-succinyl-6-hydroxy-2,-4-cyclohexadiene-1-carboxylate-synthase
MTHYKYYEANVETNQVLVLLHGFLSDSRTYYNHIDKYTDICHVITIDLPGHGEDQSSMDETWNFDYITTLLDRILDKYKDKSITLFGYSMGGRVALYYAINGHIPISNLILESTSPGIKEEANQLERRLVDDARAKVLDIAGIELFVNDWEKLPLFQSQLELPVEIQHQIRQQRLSQSPHKMAKALRDYGTGQMPNLWPRLKEIKVPTLILAGEYDEKFVQIAKKMANLIPNSKCKLISATGHTIHVEDSDEFDTMILGFLKEEQND
>NZ_CP047813.1|WP_000526687.1|1002143_1003817_-|2-succinyl-5-enolpyruvyl-6-hydroxy-3--cyclohexene-1-carboxylic-acid-synthase
MGNHKAALTKQVFTFASELYAYGVREVVISPGSRSTPLALAFEAHPNIKTWIHPDERSAAFFAVGLIKGSERPVAILCTSGTAAANYTPAIAESQISRIPLIVLTSDRPHELRSVGAPQAINQVNMFNNYVSYEFDMPIADDSKETIDAIYYQMQIASQYLYGPHKGPIHFNLPFRDPLTPDLNATELLTSEMKILPHYQKSIDASALRHILNKKKGLIIVGDMQHQEVDQILTYSTIYDLPILADPLSHLRKFDHPNVICTYDLLFRSGLDLNVDFVIRVGKPVISKKLNQWLKKTDAFQILVQNNDKIDVFPIAPDISYEISANDFFRSLMEDTTVNRVSWLEKWQCLEKKGRKEIKCYLEQATDESAFVGELIKKTSEKDALFISNSMPIRDVDNLLLNKNIDVYANRGANGIDGIVSTALGMAVHKRITLLIGDLSFYHDMNGLLMSKLNNIQMNIVLLNNDGGGIFSYLPQKESATDYFERLFGTPTGLDFEYTAKLYQFDFKRFNSVSEFKNATLLSETSTIYELITNREDNFKQHQILYQKLSEMIHDTL
>NZ_CP047813.1|WP_072399156.1|1003803_1005015_-|isochorismate-synthase
MRLNDNRTSYFGYKAIQLFKNNSKNKQSIFKDWEKLKHNITFIHPQSEKHHLRVVGGFQFSSHKSDDEWREFGLNHFVLPEVLISTDKNGTFLTYTVKRESFTVEALNDLMDLFNNISDIDVDEQIGEITRNEDIYKDDWRQLVVEAIESINNEEKIVLARRRLIKFDKDISIPYILKQAYSKEKNSYIFLLESQDSIFFSQTPEQLIKVNNKILSTKAVAGTIKRSQDEDEDTKNVEAFLKDNKNLIEHRFVVDSILHDIKPYITELHYDKTPKILKNDHLYHLYTEIKAPLKDDSYISLIDNLHPTPALGGYPKEFAMDFIEQKEFGTRGLYGAPVGYIDIYDDCEFIVAIRSMLIKKAQATLFAGCGIVKDSDPDSELAETNLKFTPMMNALGVDMNGKS
>NZ_CP047813.1|WP_001791731.1|1005091_1005196_-|hypothetical-protein
MKKDEERSEMDGYGRIRGRYCQRDIWQLKGMGFS
>NZ_CP047813.1|WP_000070966.1|1005346_1006285_+|1,4-dihydroxy-2-naphthoate-polyprenyltransferase
MSNQYQQYSTVKKYWHLMRPHTLTASVVPVLVGTAASKIYFLGSEDHIKISLFIAMLLACLLIQAATNMFNEYYDYKKGLDDHESVGIGGAIVRNGMSPELVLRLAIAFYILAAILGLFLAANSSFWLLPVGLVCMAVGYLYTGGPFPISWTPFGELFSGVFMGMFIIVIAFFIQTGNIQSYVIWLSVPIVITIGLINMANNIRDRVKDKASGRKTLPILLGKNASLTFMAIMYFIAYAFIVLTIIIKPGGSLFYLLALLSFPMPVKVIRRFKKNDTPPTMMPAMAAAGKTNTFFGLLYALGIYISALFAGI
>NZ_CP047813.1|WP_000620949.1|1006336_1006888_-|GNAT-family-N-acetyltransferase
MIRQARPEDRFDIAKLVYMVWDDMELELVKHLPKDMVLDAIEKSCVDATYRTFYQHILVYEVENKVAGCIISYSGENELKYEKAWELLDLPEEIKQYGTPLPVKEAKDDEYYIETIATFAAYRGRGIATKLLTSLLESNTHVKWSLNCDINNEAALKLYKKVGFISDGQIELYKHMYHHLIVK
>NZ_CP047813.1|WP_001788574.1|1006977_1007268_+|TM2-domain-containing-protein
MKILKLEILVFTTNLSRIIVKEDLQMKVNKAIYVIVALFLGGLGIHKFYADKFGQGLFHLLFFWTGIPTIISIIHAIFVIFTKKADKDGYIIFPKN

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Crispr_ID: NZ_CP047813_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047813_4

1098291-1098369

Orphan

Consensus_repeat	Method
CCAGCCTCTGTGTTGGGGCCCCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP047813_4

>merge|NZ_CP047813|4|1098291-1098369|CRISPRCasFinder
CCAGCCTCTGTGTTGGGGCCCCGCCAACTTGCACACTATTGTAAGCTGACTTTCCACCAGCCTCTGTGTTGGGGCCCCG

>NZ_CP047813|4|4|1098291-1098369|CRISPRCasFinder
CCAGCCTCTGTGTTGGGGCCCCG	CCAACTTGCACACTATTGTAAGCTGACTTTCCA
CCAGCCTCTGTGTTGGGGCCCCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047813.1\|WP_000711896.1\|1090596_1091172_-\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
NZ_CP047813.1\|WP_000035058.1\|1103625_1104219_-\|peptidyl-prolyl-cis-trans-isomerase	unknown	unknown	gnl\|CDD\|238908
NZ_CP047813.1\|WP_000660040.1\|1094297_1095503_+\|argininosuccinate-synthase	unknown	unknown	gnl\|CDD\|234785
NZ_CP047813.1\|WP_000758209.1\|1091187_1091712_-\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
NZ_CP047813.1\|WP_000781162.1\|1104282_1104666_+\|kinase	unknown	unknown	gnl\|CDD\|378054
NZ_CP047813.1\|WP_000148852.1\|1092616_1093948_-\|glucose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|184504
NZ_CP047813.1\|WP_000007967.1\|1091716_1092292_-\|TVP38/TMEM64-family-protein	unknown	unknown	gnl\|CDD\|223475
NZ_CP047813.1\|WP_001081626.1\|1107194_1107623_+\|Na(+)/H(+)-antiporter-subunit-B	unknown	unknown	gnl\|CDD\|183602
NZ_CP047813.1\|WP_000670752.1\|1082238_1083141_-\|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
NZ_CP047813.1\|WP_043044640.1\|1086960_1090437_-\|helicase-exonuclease-AddAB-subunit-AddB	unknown	unknown	gnl\|CDD\|213736
NZ_CP047813.1\|WP_000066053.1\|1095492_1096872_+\|argininosuccinate-lyase	unknown	unknown	gnl\|CDD\|179143
NZ_CP047813.1\|WP_043044641.1\|1097113_1098043_+\|glycerophosphodiester-phosphodiesterase	unknown	unknown	gnl\|CDD\|176543
NZ_CP047813.1\|WP_000138487.1\|1098493_1099738_-\|NAD-specific-glutamate-dehydrogenase	unknown	unknown	gnl\|CDD\|223411
NZ_CP047813.1\|WP_000167314.1\|1099846_1101037_-\|ornithine--oxo-acid-transaminase	unknown	unknown	gnl\|CDD\|179736
NZ_CP047813.1\|WP_011443624.1\|1107634_1107964_+\|Na(+)/H(+)-antiporter-subunit-C	unknown	unknown	gnl\|CDD\|181497
NZ_CP047813.1\|WP_000838033.1\|1101344_1102472_-\|NADH-dependent-flavin-oxidoreductase	unknown	unknown	gnl\|CDD\|240086
NZ_CP047813.1\|WP_043044643.1\|1107956_1109453_+\|Na+/H+-antiporter-subunit-D	unknown	unknown	gnl\|CDD\|181085
NZ_CP047813.1\|WP_043044639.1\|1083306_1086960_-\|helicase-exonuclease-AddAB-subunit-AddA	unknown	unknown	gnl\|CDD\|274299
NZ_CP047813.1\|WP_000054609.1\|1104796_1107202_+\|Na+/H+-antiporter-subunit-A	unknown	unknown	gnl\|CDD\|237155
NZ_CP047813.1\|WP_001067294.1\|1102833_1103211_-\|S1-RNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|224023

Protein	Function_ID	Function_description	E-value
NZ_CP047813.1\|WP_000711896.1\|1090596_1091172_-\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	7.44791e-54
NZ_CP047813.1\|WP_000035058.1\|1103625_1104219_-\|peptidyl-prolyl-cis-trans-isomerase	gnl\|CDD\|238908	cd01927, cyclophilin_WD40, cyclophilin_WD40: cyclophilin-type peptidylprolyl cis- trans isomerases (cyclophilins) having a WD40 domain. This group consists of several hypothetical and putative eukaryotic and bacterial proteins which have a cyclophilin domain and a WD40 domain. Function of the protein is not known.	3.93388e-65
NZ_CP047813.1\|WP_000660040.1\|1094297_1095503_+\|argininosuccinate-synthase	gnl\|CDD\|234785	PRK00509, PRK00509, argininosuccinate synthase; Provisional.	0
NZ_CP047813.1\|WP_000758209.1\|1091187_1091712_-\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	1.81012e-49
NZ_CP047813.1\|WP_000781162.1\|1104282_1104666_+\|kinase	gnl\|CDD\|378054	pfam08810, KapB, Kinase associated protein B. This bacterial protein forms an anti-parallel beta sheet with an extending alpha helical region.	8.96507e-53
NZ_CP047813.1\|WP_000148852.1\|1092616_1093948_-\|glucose-6-phosphate-isomerase	gnl\|CDD\|184504	PRK14097, pgi, glucose-6-phosphate isomerase; Provisional.	0
NZ_CP047813.1\|WP_000007967.1\|1091716_1092292_-\|TVP38/TMEM64-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	1.01759e-40
NZ_CP047813.1\|WP_001081626.1\|1107194_1107623_+\|Na(+)/H(+)-antiporter-subunit-B	gnl\|CDD\|183602	PRK12573, PRK12573, Na(+)/H(+) antiporter subunit B.	9.17513e-61
NZ_CP047813.1\|WP_000670752.1\|1082238_1083141_-\|fumarylacetoacetate-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	1.0042e-87
NZ_CP047813.1\|WP_043044640.1\|1086960_1090437_-\|helicase-exonuclease-AddAB-subunit-AddB	gnl\|CDD\|213736	TIGR02773, ATP-dependent_helicase/deoxyribonuclease_subunit_B, helicase-exonuclease AddAB, AddB subunit. DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP047813.1\|WP_000066053.1\|1095492_1096872_+\|argininosuccinate-lyase	gnl\|CDD\|179143	PRK00855, PRK00855, argininosuccinate lyase; Provisional.	0
NZ_CP047813.1\|WP_043044641.1\|1097113_1098043_+\|glycerophosphodiester-phosphodiesterase	gnl\|CDD\|176543	cd08601, GDPD_SaGlpQ_like, Glycerophosphodiester phosphodiesterase domain of Staphylococcus aureus and similar proteins. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in uncharacterized glycerophosphodiester phosphodiesterase (GP-GDE, EC 3.1.4.46) from Staphylococcus aureus, Bacillus subtilis and similar proteins. Members in this family show very high sequence similarity to Escherichia coli periplasmic phosphodiesterase GlpQ, which catalyzes the Ca2+-dependent degradation of periplasmic glycerophosphodiesters to produce sn-glycerol-3-phosphate (G3P) and the corresponding alcohols.	8.65112e-150
NZ_CP047813.1\|WP_000138487.1\|1098493_1099738_-\|NAD-specific-glutamate-dehydrogenase	gnl\|CDD\|223411	COG0334, GdhA, Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism].	0
NZ_CP047813.1\|WP_000167314.1\|1099846_1101037_-\|ornithine--oxo-acid-transaminase	gnl\|CDD\|179736	PRK04073, rocD, ornithine--oxo-acid transaminase; Provisional.	0
NZ_CP047813.1\|WP_011443624.1\|1107634_1107964_+\|Na(+)/H(+)-antiporter-subunit-C	gnl\|CDD\|181497	PRK08600, PRK08600, putative monovalent cation/H+ antiporter subunit C; Reviewed.	3.20641e-61
NZ_CP047813.1\|WP_000838033.1\|1101344_1102472_-\|NADH-dependent-flavin-oxidoreductase	gnl\|CDD\|240086	cd04735, OYE_like_4_FMN, Old yellow enzyme (OYE)-related FMN binding domain, group 4. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Other members of OYE family include trimethylamine dehydrogenase, 2,4-dienoyl-CoA reductase, enoate reductase, pentaerythriol tetranitrate reductase, xenobiotic reductase, and morphinone reductase.	0
NZ_CP047813.1\|WP_043044643.1\|1107956_1109453_+\|Na+/H+-antiporter-subunit-D	gnl\|CDD\|181085	PRK07691, PRK07691, putative monovalent cation/H+ antiporter subunit D; Reviewed.	0
NZ_CP047813.1\|WP_043044639.1\|1083306_1086960_-\|helicase-exonuclease-AddAB-subunit-AddA	gnl\|CDD\|274299	TIGR02785, ATP-dependent_helicase/nuclease_subunit_A, helicase-exonuclease AddAB, AddA subunit, Firmicutes type. AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP047813.1\|WP_000054609.1\|1104796_1107202_+\|Na+/H+-antiporter-subunit-A	gnl\|CDD\|237155	PRK12645, PRK12645, monovalent cation/H+ antiporter subunit A; Reviewed.	0
NZ_CP047813.1\|WP_001067294.1\|1102833_1103211_-\|S1-RNA-binding-domain-containing-protein	gnl\|CDD\|224023	COG1098, VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) [Translation, ribosomal structure and biogenesis].	3.22125e-44

>NZ_CP047813.1|WP_043044641.1|1097113_1098043_+|glycerophosphodiester-phosphodiesterase
MTNSSKSFTKFMAASAVFTMGFLSVPTAGAEQTNQIANKPQAIQWHTNLTNERFTTIAHRGASGYAPEHTFQAYDKSHNELKASYIEIDLQRTKDGHLVAMHDETVNRTTNGHGKVEDYALDELKQLDAGSWFNKKYPKYARASYKNAKVPTLDEILERYGPNANYYIETKSPDVYPGMEEQLLASLKKHHLLNNNKLKNGHVMIQSFSDESLKKIHRQNKHVPLVKLVDKGELQQFNDQRLKEIRSYAIGLGPDYTDLTEQNTHHLKDLGFIVHPYTVNEKADMLRLNKYGVDGVFTNFADKYKEVIK
>NZ_CP047813.1|WP_000066053.1|1095492_1096872_+|argininosuccinate-lyase
MSNKAWGGRFEVQPEEWVDDFNASITFDQTLIDQDIEGSIAHATMLANQGIISQQDSEQIIQGLKSIQHDYHQDQIQFSASLEDIHLNIEHELIKRIGDAGGKLHTGRSRNDQVATDMHLYTKKQVQDIIALIKSLQSVIVDIASNNVDTIMPGYTHLQRAQPISFAHHIMTYFWMLQRDQQRFEDSLKRIDINPLGAAALSGTTYPIDRHETTALLNFGSLYENSLDAVSDRDYIIETLHNISLTMVHLSRFAEEIIFWSTDEAKFITLSDAFSTGSSIMPQKKNPDMAELIRGKVGRTTGHLMSMLMTLKGLPLAYNKDMQEDKEGLFDAVHTIKGSLRIFEGMIQTMTINKERLNQTVKEDFSNATELADYLVTKNIPFRTAHEIVGKIVLECIQQGHYLLDVPLATYQQHHSSIDADIYDYLQPENCLKRRQSYGSTGQSSVKQQLDVAKQLLSQ
>NZ_CP047813.1|WP_000660040.1|1094297_1095503_+|argininosuccinate-synthase
MKEKIVLAYSGGLDTSVAVQWLIDKGYDVVACCLDVGEGKDLDIVYKKALDMGAVECHIIDATKEFSDEYVSYAIKGNLMYENAYPLVSALSRPLIAKKLVEIAEKTNSVGIAHGCTGKGNDQVRFEVAIKALNPSLKAFAPVREWAWSREEEIDYAIKHNIPVSINHDSPYSIDQNLWGRANECGILEDPYAAPPEDAFDLTNALEETPDAADEIILTFDKGIPVQIDGKTYELDDLILTLNALAGKHGIGRIDHVENRLVGIKSREIYEAPAAEVILKAHKALETITLTKDVAHFKPIIEKQFAEQLYNGLWFSPLTDSLKLFIDSTQQYVSGDVRIKLFKGNAIVNGRKSPYTLYDEKLATYTKEDAFNQDAAVGFIDIYGLPTQVNAMLHGGYSNEQ
>NZ_CP047813.1|WP_000148852.1|1092616_1093948_-|glucose-6-phosphate-isomerase
MTHIQLDFSKTLEFFGEHELKQQQEIVKSIHKTIHEGTGAGSDFLGWVDLPVDYDKEEFSRIVEASKRIKENSDVLVVIGIGGSYLGARAAIEMLTSSFRNSNEYPEIVFVGNHLSSTYTKELVDYLADKDFSVNVISKSGTTTEPAVAFRLFKQLVEERYGKEEAQKRIFATTDKEKGALKQLATNEGYETFIVPDDVGGRYSVLTAVGLLPIATAGINIEAMMIGAAKAREELSSDKLEDNIAYQYATIRNILYAKGYTTEMLINYEPSMQYFNEWWKQLFGESEGKDFKGIYPSSANYTTDLHSLGQYVQEGRRFLFETVVKVNHPKYDITIEKDSDDLDGLNYLAGKTIDEVNTKAFEGTLLAHTDGGVPNMVVNIPQLDEETFGYVVYFFELACAMSGYQLGVNPFNQPGVEAYKQNMFALLGKPGFEDLKKELEERL
>NZ_CP047813.1|WP_000007967.1|1091716_1092292_-|TVP38/TMEM64-family-protein
MSFHQVEEWFEIFRQFGYLPGFILLYIRAIIPVFPLALYILINIQAYGPILGILISWLGLISGTFTVYLICKRLVNTERMQRIKQRTAVQRLISFIDRQGLIPLFILLCFPFTPNTLINFVASLSHIRPKYYFIVLASSKLVSTIILGYLGKEITTILTHPLRGILMLVVLVVFWIVGKKLEQHFMGSKKE
>NZ_CP047813.1|WP_000758209.1|1091187_1091712_-|signal-peptidase-I
MKKVVKYLISLILAIIIVLFVQTFVIVGHVIPNNDMSPTLNKGDRVIVNKIKVTFNQLNNGDIITYRRGNEIYTSRIIAKPGQSMAFRQGQLYRDDRPVDASYAKNRKIKDFSLRNFKELDGDIIPPNNFVVLNDHDNNQHDSRQFGLIDKKDIIGNISLRYYPFSKWTIQFKS
>NZ_CP047813.1|WP_000711896.1|1090596_1091172_-|signal-peptidase-I
MKKELLEWIISIAVAFVILFIVGKFIVTPYTIKGESMDPTLKDGERVAVNIIGYKTGGLEKGNVVVFHANKNDDYVKRVIGVPGDKVEYKNDTLYVNGKKQDEPYLNYNLKHKQGDYITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRAFGLIDEDQIVGKVSFRFWPFSEFKHNFNPENTKN
>NZ_CP047813.1|WP_043044640.1|1086960_1090437_-|helicase-exonuclease-AddAB-subunit-AddB
MTLHAYLGRAGTGKSTKMLTEIKQKMKADPLGDPIILIAPTQSTFQLEQAFVNDPELNGSLRTEVLHFERLSHRIFQEVGSYSEQKLSKAATEMMIYNIVQEQQKYLKLYQSQAKYYGFSEKLTEQIQDFKKYAVTPEHLEHFIADKNMQTRTKNKLEDIALIYREFEQRIQNEFITGEDSLQYFIDCMPKSEWLKRADIYIDGFHNFSTIEYLIIKGLIKYAKSVTIILTTDGNHDQFSLFRKPSEVLRHIEEIANELNISIERQYFNQLYRFNNQDLKHLEQEFDVLQINRVACQGHINILESATMREEINEIARRIIVDIRDKQLRYQDIAILYRDESYAYLFDSILPLYNIPYNIDTKRSMTHHPVMEMIRSLIEVIQSNWQVNPMLRLLKTDVLTASYLKSAYLVDLLENFVLERGIYGKRWLDDELFNVEHFSKMGRKAHKLTEDERNTFEQVVKLKKDVIDKILHFEKQMSQAETVKDFATAFYESMEYFELPNQLMTERDELDLNGNHEKAEEIDQIWNGLIQILDDLVLVFGDEPMSMERFLEVFDIGLEQLEFVMIPQTLDQVSIGTMDLAKVDNKQHVYLVGMNDGTMPQPVTASSLITDEEKKYFEQQANVELSPTSDILQMDEAFVCYVAMTRAKGDVTFSYSLMGSSGDDKEISPFLNQIQSLFNQLEITNIPQYHEVNPLSLMQHAKQTKITLFEALRAWLDDEIVADSWLDAYQVIRDSDHLNQGLDYLMSALTFDNETVKLGETLSKDLYGKEINASVSRFEGYQQCPFKHYASHGLKLNERTKYELQNFDLGDIFHSVLKYISERINGDFKQLDLKKIRQLTNEALEEILPKVQFNLLNSSAYYRYLSRRIGAIIETTLSALKYQGTYSKFMPKHFETSFRRKPRTNDELIAQTLTTTQGIPINIRGQIDRIDTYTKNDTSFVNIIDYKSSEGSATLDLTKVYYGMQMQMMTYMDIVLQNKQRLGLTDIVKPGGLLYFHVHEPRIKFKSWSDIDEDKLEQDLIKKFKLSGLVNADQTVIDALDIRLEPKFTSDIVPVGLNKDGSLSKRGSQVADEATIYKFIQHNKENFIETASNIMDGHTEVAPLKYKQKLPCAFCSYQSVCHVDGMIDSKRYRTVDETINPIEAIQNININDEFGGEQ
>NZ_CP047813.1|WP_043044639.1|1083306_1086960_-|helicase-exonuclease-AddAB-subunit-AddA
MTIPEKPQGVIWTDAQWQSIYATGQDVLVAAAAGSGKTAVLVERIIQKILRDGIDVDRLLVVTFTNLSAREMKHRVDQRIQEASIADPANAHLKNQRIKIHQAQISTLHSFCLKLIQQHYDVLNIDPNFRTSSEAENILLLEQTIDEVIEQHYDILDPAFIELTEQLSSDRSDDQFRMIIKQLYFFSVANPNPTNWLDQLVTPYEEEAQQAQLIQLLTDLSKVFITAAYDALNKAYDLFSMMDSVDKHLAVIEDERRLMGRVLEGGFIDIPYLTGHEFGARLPNVTAKIKEANEMMVDALEDAKLQYKKYKSLIDKVKSDYFSREADDLKADMQQLAPRVKYLARIVKDVMSEFNRKKRSKNILDFSDYEHFALQILTNEDGSPSEIAESYRQHFQEILVDEYQDTNRVQEKILSCIKTGDEHNGNLFMVGDVKQSIYKFRQADPSLFIEKYQRFTIDGDGTGRRIDLSQNFRSRKEVLSTTNYIFKHMMDEQVGEVKYDEAAQLYYGAPYDESDHPVNLKVLVEADQEHSDLTGSEQEAHFIVEQVKDILEHQKVYDMKTGSYRSATYKDIVILERSFGQARNLQQAFKNEDIPFHVNSREGYFEQTEVRLVLSFLRAIDNPLQDIYLVGLMRSVIYQFKEDELAQIRILSPNDDYFYQSIVNYINDEAADAILVDKLKMFLSDIQSYQQYSKDHPVYQLIDKFYNDHYVIQYFSGLIGGRGRRANLYGLFNKAIEFENSSFRGLYQFIRFIDELIERGKDFGEENVVGPNDNVVRMMTIHSSKGLEFPFVIYSGLSKDFNKRDLKQPVILNQQFGLGMDYFDVDKEMAFPSLASVAYKAVAEKELVSEEMRLVYVALTRAKEQLYLIGRVKNDKSLLELEQLSISGEHIAVNERLTSPNPFHLIYSILSKHQSASIPDDLKFEKDIAQVEDSSRPNVNISIIYFEDVSTETILDNNEYRSVNQLETMQNGNEDVKAQIKHQLDYQYPYVNDTKKPSKQSVSELKRQYETEESGTSYERVRQYRIGFSTYERPKFLSEQGKRKANEIGTLMHTVMQHLPFKKERISEVELHQYIDGLIDKHIIEADAKKDIRMDELMTFINSELYSIIAEAEQVYRELPFVVNQALVDQLPQGDEDVSIIQGMIDLIFVKDGVHYFVDYKTDAFNRRRGMTDEEIGTQLKNKYKIQMKYYQNTLQTILNKEVKGYLYFFKFGTLQL
>NZ_CP047813.1|WP_000670752.1|1082238_1083141_-|fumarylacetoacetate-hydrolase-family-protein
MKFLSFKYNDKTSYGVKVKREDAVWDLTQVFADFAEGDFHPKTLLAGLQQNHTLDFQEQVRKAVVAAEDSGKAEDYKISFNDIEFLPPVTPPNNVIAFGRNYKDHANELNHEVEKLYVFTKAASSLTGDNATIPNHKDITDQLDYEGELGIVIGKSGEKIPKALALDYVYGYTIINDITDRKAQSEQDQAFLSKSLTGGCPMGPYIVTKDELPLPENVNIVTKVNNEIRQDGNTGEMILKIDELIEEISKYVALHPGDIIATGTPAGVGAGMQPPKFLQPGDEVKVTIDNIGTLTTYIAK
>NZ_CP047813.1|WP_000138487.1|1098493_1099738_-|NAD-specific-glutamate-dehydrogenase
MTENNNLVTSTQGIIKEALHKLGFDEGMYDLIKEPLRMLQVRIPVRMDDGTVKTFTGYRAQHNDAVGPTKGGVRFHPDVDEEEVKALSMWMTLKCGIVNLPYGGGKGGIVCDPRQMSIHEVERLSRGYVRAISQFVGPNKDIPAPDVFTNSQIMAWMMDEYSALDKFNSPGFITGKPIVLGGSHGRDRSTALGVVIAIEQAAKRRNMQIEGAKVVIQGFGNAGSFLAKFLYDLGAKIVGISDAYGALHDPNGLDIDYLLDRRDSFGTVTNLFEETISNKELFELDCDILVPAAISNQITEDNAHDIKASIVVEAANGPTTPEATRILTERGILLVPDVLASAGGVTVSYFEWVQNNQGYYWSEEEVNEKLREKLEAAFDTIYELSQNRKIDMRLAAYIIGIKRTAEAARYRGWA
>NZ_CP047813.1|WP_000167314.1|1099846_1101037_-|ornithine--oxo-acid-transaminase
MTKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPKIIQALKDQADKVTLVSRAFHSDNLGEWYEKICKLAGKDKALPMNTGAEAVETALKAARRWAYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRGYGPLLDGFRKVDFGDVDALKAAINENTAAVLVEPIQGEAGINIPPEGYLKAIRELCDEHNVLFIADEIQAGLGRSGKLFATDWDNVKPDVYILGKALGGGVFPISVVLADKEVLDVFTPGSHGSTFGGNPLACAASIAALDVIVDEDLPGRSLELGDYFKEQLKQIDHPSIKEVRGRGLFIGVELNESARPYCEALKEEGLLCKETHDTVIRFAPPLIITKEELDLALEKIRHVFQ
>NZ_CP047813.1|WP_000838033.1|1101344_1102472_-|NADH-dependent-flavin-oxidoreductase
MKSKYEPLFDKVELPNGVELRNRFVLAPLTHISSNDDGTISDVELPYIEKRSQDVGITINAASNVSDVGKAFPGQPSIAHDSDIEGLKRLATAMKKNGAKALVQIHHGGAQALPELTPGGDVVAPSPISLKSFGQKQEHSAREMTNEEIEQAIKDFGEATRRAIEAGFDGVEIHGANHYLIHQFVSPYYNRRNDVWANQYKFPVAVIEEVLKAKEAYGNKDFIVGYRLSPEEAESPGITMEITEELVNKISHMPIDYIHVSMMDTHATTREGKYAGQERLPLIHKWINGRMPLIGIGSIFTADEALDAVENVGVDLVAIGRELLLDYQFVEKIKDGREDEIINYFDPEREDNHHLTPNLWHQFNEGFYPLPRKDK
>NZ_CP047813.1|WP_001067294.1|1102833_1103211_-|S1-RNA-binding-domain-containing-protein
MNNYKIGQHIKVRVTGIQPYGAFVETPNHTEGLIHISEIMDDYVHNLKKFLSEGQIVKAKILSIDDEGKLNLSLKDNDYFKNYERKKEKQSVLDEIRETEKYGFQTLKERLPIWIKQSKRAIRND
>NZ_CP047813.1|WP_000035058.1|1103625_1104219_-|peptidyl-prolyl-cis-trans-isomerase
MANYPQLNKEVQQGEIKVVMHTNKGDMTFKLFPNIAPKTVENFVTHAKNGYYDGITFHRVINDFMIQGGDPTATGMGGESIYGGAFEDEFSLNAFNLYGALSMANSGPNTNGSQFFIVQMKEVPQNMLSQLADGGWPQPIVDAYGEKGGTPWLDQKHTVFGQIIDGETTLEDIANTKVGPQDKPLHDVVIESIDVEE
>NZ_CP047813.1|WP_000781162.1|1104282_1104666_+|kinase
MKLYRFSHKTGSYGVTIVEENGDDVLVKVEQVIKHPKQGDLHNPTETEGVFFHERKALSHFEKRYTKRSQLRDFNVDVLRYEDSLQQAITDLETKLKAQQTKHAEMSLASLARLKEDYSLQYKENFK
>NZ_CP047813.1|WP_000054609.1|1104796_1107202_+|Na+/H+-antiporter-subunit-A
MSLLHIAVILPLIFALIIPILYRFFKRIHLGWFVLPVPIVIFIYMLTLIKTTMSGNTVMKTLNWMPHFGMNFDLYLDGLGLLFSLLISGIGSLVVLYSIGYLSKSEQLGNFYCYLLLFMGAMLGVVLSDNVIILYLFWELTSFSSFLLISFWRERQASIYGAQKSLIITVFGGLSLLGGIILLAIPTQSFSIQYMIQHASEIQNSPFFIFAMILIMIGAFTKSAQFPFYIWLPDAMEAPTPVSAYLHSATMVKAGLYLIARMTPIFAASQGWVWTVTLVGLITLFWASLNATKQQDLKGILAFSTVSQLGMIMAMLGIGAISYHYQGDDSKIYAAAFTAAIFHLINHATFKGALFMITGAVDHSTGTRDVKKLGGLLTIMPISFTITVITALSMAGVPPFNGFLSKESFLETTFTASQANLFSVDTLGYLFPIIGIVGSVFTFVYSIKFIMHIFFGQYKPEQLPKKAHEVSILMLLSPAILATLVIVFGLFPGILTNSIIEPATSSINHTVIDDVEFHMFHGLTPAFLSTLVIYILGILLIVTFSYWVKLLQRQPGKLTFNYWYNRSANVIPNYSEKMTNSYVTDYSRNNLVIIFGALILLTFVTIFSVPFNINFKDVSPIRIFEVCIVILLLSAAFLILFAKSRLFSIIMLSAVGYAVSVLFIFFKAPDLALTQFVVESISTALFLLCFYHLPNLNRYNEKRSFQLTNALIAGGVGLSVIIIGLIAYGNRHFESISKFYQEHVYDLAHGKNMVNVILVDFRGMDTLFESSVLGIAGLAVYTMIKLRKKRQTQGNEVKNHE
>NZ_CP047813.1|WP_001081626.1|1107194_1107623_+|Na(+)/H(+)-antiporter-subunit-B
MNRQQNDLILQFAAVIIFFMVMVFGFSLFLAGHYTPGGGFVGGLLFASSLVIITIAFDIETMRKIFPLDFKILIGIGLVFCIATPIASWFLGKNFFTHVTFDIPLFILEPVHMTTAVFFDFGVLCAVVGTVMTIIISIGENE
>NZ_CP047813.1|WP_011443624.1|1107634_1107964_+|Na(+)/H(+)-antiporter-subunit-C
MIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLITMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIAFATTAFFLVLAFRTYKELGTDNVESMKGVPEDD
>NZ_CP047813.1|WP_043044643.1|1107956_1109453_+|Na+/H+-antiporter-subunit-D
MIESNMLVLTLVIPVITAILLVFIGKRPIIKRYVALGGTLLTLVAAIINLANVVKHGPIRVELGSWKAPYSIVFVLDIFSALLIITSIIITAIVILYSYQTIGIERERYYYYFSVLFMLIGIIGAFTTGDIFNLFVFFEVFLMSSYFLLVIGSTKIQLQETIKYVLVNVVSSSFFVMGVAILYSVVGTLNLADISNKLANLSAHDSGLVNIVFILFIFVFATKAGVFPMFVWLPSAYYAPPIPIIAFFGALLTKVGVYAIARTLSLFFSDNVSFSHYVILFLALLTIIFGCVGAVAYANIKKIILYNVMIAVGVILVGVAMMTESGMIGAIYYTLHDMLVKLALFLLIGIMIKITGTADLRQFGGLIKRYPVLGWSFFIAALSLAGIPPLSGFYGKFFIVQSTFERGFYLSGVIVLLSSLVVLYSVIRIFLQGFFGQPKGYGLNNKVDVKYLTTIAIVAVVITVLYGLSADYLYPMVKAGAETFYNPSTYVKAVLGGK

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Crispr_ID: NZ_CP047813_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047813_5

1147424-1147505

Orphan

Consensus_repeat	Method
TTCTACAGGCAATGCAAGTTGGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP047813_5

>merge|NZ_CP047813|5|1147424-1147505|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGGATGGGCCCCAACAAAGAGAAATTGGATTCTCAATTTCTACAGACAATGCAAGTTGGGG

>NZ_CP047813|5|5|1147424-1147505|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGG	ATGGGCCCCAACAAAGAGAAATTGGATTCTCAAT
TTCTACAGACAATGCAAGTTGGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047813.1\|WP_000807670.1\|1137815_1139057_-\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|131034
NZ_CP047813.1\|WP_001183867.1\|1141665_1142517_+\|DUF368-domain-containing-protein	unknown	unknown	gnl\|CDD\|224946
NZ_CP047813.1\|WP_000168845.1\|1140576_1141338_-\|Fe-S-cluster-assembly-ATPase-SufC	unknown	unknown	gnl\|CDD\|223473
NZ_CP047813.1\|WP_000569884.1\|1152480_1152975_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|372596
NZ_CP047813.1\|WP_043044650.1\|1144860_1145886_-\|methionine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224058
NZ_CP047813.1\|WP_043044651.1\|1147608_1148487_-\|DUF1963-domain-containing-protein	unknown	unknown	gnl\|CDD\|226395
NZ_CP047813.1\|WP_043044649.1\|1143333_1144155_-\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224381
NZ_CP047813.1\|WP_000205572.1\|1139171_1140479_-\|Fe-S-cluster-assembly-protein-SufD	unknown	unknown	gnl\|CDD\|223791
NZ_CP047813.1\|WP_000422908.1\|1150173_1150713_-\|nitroreductase	unknown	unknown	gnl\|CDD\|380312
NZ_CP047813.1\|WP_043044652.1\|1149703_1150024_+\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP047813.1\|WP_000255561.1\|1153129_1153747_+\|amino-acid-transporter	unknown	unknown	gnl\|CDD\|224198
NZ_CP047813.1\|WP_000290490.1\|1148665_1149046_-\|glycine-cleavage-system-protein-GcvH	unknown	unknown	gnl\|CDD\|234918
NZ_CP047813.1\|WP_000662306.1\|1148488_1148602_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047813.1\|WP_043044653.1\|1151659_1152082_+\|organic-hydroperoxide-resistance-protein	unknown	unknown	gnl\|CDD\|274649
NZ_CP047813.1\|WP_000752917.1\|1142750_1142945_-\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|225777
NZ_CP047813.1\|WP_001065801.1\|1146135_1146432_-\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP047813.1\|WP_000150016.1\|1150795_1151512_-\|type-I-3-dehydroquinate-dehydratase	unknown	unknown	gnl\|CDD\|184156
NZ_CP047813.1\|WP_001018962.1\|1146424_1146811_-\|topiosmerase	unknown	unknown	gnl\|CDD\|224572
NZ_CP047813.1\|WP_000589549.1\|1149203_1149560_-\|arsenate-reductase-family-protein	unknown	unknown	gnl\|CDD\|239334
NZ_CP047813.1\|WP_000520233.1\|1144172_1144868_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224922

Protein	Function_ID	Function_description	E-value
NZ_CP047813.1\|WP_000807670.1\|1137815_1139057_-\|cysteine-desulfurase	gnl\|CDD\|131034	TIGR01979, Probable_cysteine_desulfurase, cysteine desulfurases, SufSfamily. This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NZ_CP047813.1\|WP_001183867.1\|1141665_1142517_+\|DUF368-domain-containing-protein	gnl\|CDD\|224946	COG2035, COG2035, Predicted membrane protein [Function unknown].	1.28839e-76
NZ_CP047813.1\|WP_000168845.1\|1140576_1141338_-\|Fe-S-cluster-assembly-ATPase-SufC	gnl\|CDD\|223473	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones].	1.29081e-150
NZ_CP047813.1\|WP_000569884.1\|1152480_1152975_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|372596	pfam13420, Acetyltransf_4, Acetyltransferase (GNAT) domain.	2.53639e-47
NZ_CP047813.1\|WP_043044650.1\|1144860_1145886_-\|methionine-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	2.31964e-169
NZ_CP047813.1\|WP_043044651.1\|1147608_1148487_-\|DUF1963-domain-containing-protein	gnl\|CDD\|226395	COG3878, COG3878, Uncharacterized protein conserved in bacteria [Function unknown].	1.67562e-73
NZ_CP047813.1\|WP_043044649.1\|1143333_1144155_-\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	9.4577e-113
NZ_CP047813.1\|WP_000205572.1\|1139171_1140479_-\|Fe-S-cluster-assembly-protein-SufD	gnl\|CDD\|223791	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones].	8.11734e-136
NZ_CP047813.1\|WP_000422908.1\|1150173_1150713_-\|nitroreductase	gnl\|CDD\|380312	cd02135, YdjA-like, nitroreductase family protein similar to Escherichia coli YdjA. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase YdjA from Escherichia coli. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer. Members of this family are also called NADH dehydrogenase, oxygen-insensitive NAD(P)H nitrogenase or dihydropteridine reductase.	2.10032e-49
NZ_CP047813.1\|WP_043044652.1\|1149703_1150024_+\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	3.81766e-24
NZ_CP047813.1\|WP_000255561.1\|1153129_1153747_+\|amino-acid-transporter	gnl\|CDD\|224198	COG1279, COG1279, Lysine efflux permease [General function prediction only].	9.12336e-62
NZ_CP047813.1\|WP_000290490.1\|1148665_1149046_-\|glycine-cleavage-system-protein-GcvH	gnl\|CDD\|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	1.28962e-69
NZ_CP047813.1\|WP_043044653.1\|1151659_1152082_+\|organic-hydroperoxide-resistance-protein	gnl\|CDD\|274649	TIGR03561, organ_hyd_perox, peroxiredoxin, Ohr subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein Ohr, or organic hydroperoxide resistance protein. [Cellular processes, Detoxification].	9.85083e-61
NZ_CP047813.1\|WP_000752917.1\|1142750_1142945_-\|CsbD-family-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	5.95583e-07
NZ_CP047813.1\|WP_001065801.1\|1146135_1146432_-\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	7.01368e-14
NZ_CP047813.1\|WP_000150016.1\|1150795_1151512_-\|type-I-3-dehydroquinate-dehydratase	gnl\|CDD\|184156	PRK13575, PRK13575, type I 3-dehydroquinate dehydratase.	6.4154e-149
NZ_CP047813.1\|WP_001018962.1\|1146424_1146811_-\|topiosmerase	gnl\|CDD\|224572	COG1658, COG1658, Small primase-like proteins (Toprim domain) [DNA replication, recombination, and repair].	2.45102e-36
NZ_CP047813.1\|WP_000589549.1\|1149203_1149560_-\|arsenate-reductase-family-protein	gnl\|CDD\|239334	cd03036, ArsC_like, Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX) function as protein disulfide oxidoreductases, altering the redox state of target proteins via the reversible oxidation of the active site dithiol. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from glutathione via GRX, through a single catalytic cysteine.	1.06191e-56
NZ_CP047813.1\|WP_000520233.1\|1144172_1144868_-\|ABC-transporter-permease	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	9.67625e-100

>NZ_CP047813.1|WP_001018962.1|1146424_1146811_-|topiosmerase
MAIVNKVIIVEGKSDKKRVQQVIAEPVNIICTHGTMSIDKLDDMIESLYDKQVFVLADSDDEGDRIRNWFKRYLSESEHIFIDKTYCQVANCPKQYLAHVLSKHGFTCKKETPLLPNINNERLVLVNE
>NZ_CP047813.1|WP_001065801.1|1146135_1146432_-|thioredoxin-family-protein
MNNSLDIKDVTTFYEEDKHLIFGYTPTCGTCKVSERMLDIANEILQLPLLKIDLNFYPQFCKDMQIMSTPILLLMNKDKEVKRIYAFKSVTDLLENLK
>NZ_CP047813.1|WP_043044650.1|1144860_1145886_-|methionine-ABC-transporter-ATP-binding-protein
MIELKEVVKEYRIKNKEVLAVDHVNLSIRAGSIYGVIGFSGAGKSTLIRMFNHLEAPTSGEVIIDGDHIGQLSKNGLRAKRQKVSMIFQHFNLLWSRTVLKNIMFPLEIAGVPRRRAKQKALELVELVGLKGREKAYPSELSGGQKQRVGIARALANDPTVLLCDEATSALDPQTTDEILDLLLKIREQQNLTIVLITHEMHVIRRICDEVAVMESGKVIEQGPVTQVFENPQHTVTKRFVKDDLNDDFETSLTELEPLEKDAYIVRLVFAGSTTTEPIVSSLSTAYDIKINILEANIKNTKNGTVGFLVLHIPYISSVDFGKFEKELIERQVKMEVLRHG
>NZ_CP047813.1|WP_000520233.1|1144172_1144868_-|ABC-transporter-permease
MGKSFSEIINEMITMPNIQWPEVWTAIVETLYMTVVSTIFAFILGLILGVLLFLSAKGKSIGARLFYSIVSFIVNLFRAIPFIILILLLIPFTSLILGTISGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVIGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQFIGDWLTNKLDKR
>NZ_CP047813.1|WP_043044649.1|1143333_1144155_-|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein
MKKLFGLILVLTFAVALAACGNGSKSGSDDKKITVGASPAPHAEILEKAKPLLEKKGYELDIKTINDYTTPNKLLDKGEIDANYFQHTPYLNTEKKDKGYKIVSAGDVHLEPMAVYSKKYKSLKELPKGATVYVSNNPAEQGRFLKFFVDAGLIKIKKGVKIEDAKFSDITENKKDIKFNNKQSAEFLPKIYQNEDADAVIINSNFAIEQKLNPKKDSIAVESAKDNPYANLIAVKEGHQDDKKIKALIEVLQSKDIQDFINEKYNGAVIPAK
>NZ_CP047813.1|WP_000752917.1|1142750_1142945_-|CsbD-family-protein
MADESKFEQAKGNVKETVGNVTDNKNLENEGKEDKASGKAKEFVENAKEKATDFIDKVKGNKGE
>NZ_CP047813.1|WP_001183867.1|1141665_1142517_+|DUF368-domain-containing-protein
MQQFKWINILKGFAMGTSDLVPGVSGGTIALLLGIYNQFISSISGIFSRRFWPSFTFLIPIIIGMLLAMGSLSNLFNYLLSQHHIPTMFFFGGLIIGIVPYLLKISNYKTSFTTKHYMMVIAGIAILIVITLMNNGDKHAGETLTLSTSLIIKYFIAGMCASSAMLLPGISGSFMLLVFGVYGTVMLAISEVVKLNFTGLPILLAVGFGVLAGFIISSKIIQYFLTHHKLMTFALIIGFVVGSLFAVFPGLPTNIVMWFVSLVVFIIGFIVSLTLGRITAENE
>NZ_CP047813.1|WP_000168845.1|1140576_1141338_-|Fe-S-cluster-assembly-ATPase-SufC
MASTLEIKDLHVSIEDKEILKGVNLTINTDEIHAIMGPNGTGKSTLSSAIMGHPSYEVTKGEVLLDGVNILELEVDERAKAGLFLAMQYPSEITGVTNADFMRSAINAKREEGQEINLMQFIKKLDKNMDFLDIDKDMAQRYLNEGFSGGEKKRNEILQLMMLEPKFAILDEIDSGLDIDALKVVSKGINQMRGENFGALMITHYQRLLNYITPDKVHVMYAGKVVKSGGPELAKRLEEEGYEWVKEEFGSAE
>NZ_CP047813.1|WP_000205572.1|1139171_1140479_-|Fe-S-cluster-assembly-protein-SufD
MTTDILNISEEQLVDYSKAHNEPSWMTELRKKALKLTETLEMPKPDKTKLRKWDFDSFKQHDVKGDVYQSLSQLPESVREIIDVDHSKNLVIQHNNTIAYTQVDDNASKDGVIVEGLADALMNHSDLVQKYFMKDAVTVDEHRITALHTALVNGGVFVYVPKNVVVEHPVQYVVLHDDENASFYNHVIIVTEESAEVTYVENYLSNASGEGNQLNIISEVIAGANSNITYGSVDYMDKGFTGHIIRRGITEADASINWALGLMNEGSQIIDNTTNLFGDRSTSSLKSVVVGTGEQKINLTSKIVQYGKETDGYILKHGVMKEHASSVFNGIGYIKHGGTKSIANQESRVLMLSEHARGDANPILLIDEDDVQAGHAASVGRVDPDQLYYLMSRGISQREAERLVIHGFLDPVVRELPIEDVKRQLREVIERKVSK
>NZ_CP047813.1|WP_000807670.1|1137815_1139057_-|cysteine-desulfurase
MAEHSFDVNEVIKDFPILDQKVNGKRLAYLDSTATSQTPVQVLNVLEDYYKRYNSNVHRGVHTLGSLATDGYENARETVRRFINAKYFEEIIFTRGTTASINLVAHSYGDANVEEGDEIVVTEMEHHANIVPWQQLAKRKNATLKFIPMTADGELNIEDIKQTINDKTKIVAIAHISNVLGTINDVKTIAEIAHQHGAIISVDGAQAAPHMKLDMQEMNADFYSFSGHKMLGPTGIGVLFGKRELLQKMEPIEFGGDMIDFVSKYDATWADLPTKFEAGTPLIAQAIGLAEAIRYLERIGFDAIHKYEQELTIYAYEQMSAIEGIEIYGPPKDRRAGVITFNLQDVHPHDVATAVDTEGVAVRAGHHCAQPLMKWLNVSSTARASFYIYNTKEDIDQLINALKQTKEFFSYEF
>NZ_CP047813.1|WP_043044651.1|1147608_1148487_-|DUF1963-domain-containing-protein
MLNIQDVSHLSKKEQKAYNRFVESVENGNLPVLPCIEMDLKEMKEETLNQSKIGGMPFLKSFKDIPLDENNVPMVLLAQINLDNLPEQQELFPVKEGILQFWISSEDQMYGMSENLKGNNINSGLVYIKEPITDLSLENIQEHLKSLDADNEDIPFSGAFSIKFRLSKQTITCTDYKYDEDVLALWNKVNPSFALKSMFGGYDELMEPVCNTFTAKEPFNQLGGYPYFDQIDPRTNDQELKMYDRVLLQIDSTRDGNSSIIWGDLGIANILVKSTDLEAMKFDDYMYSWDCS
>NZ_CP047813.1|WP_000662306.1|1148488_1148602_-|hypothetical-protein
MKENLLGTIIWSIATFYYSRMMKIMNLAILKIKIGGS
>NZ_CP047813.1|WP_000290490.1|1148665_1149046_-|glycine-cleavage-system-protein-GcvH
MAVPNELKYSKEHEWVKVEGNVATIGITEYAQSELGDIVFVELPETDDEINEGDTFGSVESVKTVSELYAPISGKVVEVNEELEDSPEFVNESPYEKAWMVKVEISDESQIEALLTAEKYSKMIGE
>NZ_CP047813.1|WP_000589549.1|1149203_1149560_-|arsenate-reductase-family-protein
MIKFYQYKNCTTCKKAAKFLDEYGVSYEPIDIVQHTPTINEFKTIIANTGVEINKLFNTHGAKYRELDLKNKLQTLSDDEKLELLSSDGMLVKRPLAVMGDKITLGFKEDQYKETWLA
>NZ_CP047813.1|WP_043044652.1|1149703_1150024_+|thioredoxin-family-protein
MQAIKSNESFKSVINSDTPVIVKFEAGWCPDCRAMDLWIDPIVEQYNDYPWYTVNRDELEDVVVENEVMGIPSLLVFKNGDKIAHLHSANAKSPEQVESFLAETFK
>NZ_CP047813.1|WP_000422908.1|1150173_1150713_-|nitroreductase
MELQQAIANRRSVKKFKRDMHIDDALLYQAIEKAADAPNHGMREPWRVVHVPKDRLGDMSKDISKFAFPNELDKQQCHYDAVTKLGGMLLLILKTDPRQRQNDENYFAFGAYAQNLMLLLYEAGIGTCWKSPLYIYDPKVRKTLGIKKDEVLAGFLYLTDLEEDMPKAPRKNRNLITLY
>NZ_CP047813.1|WP_000150016.1|1150795_1151512_-|type-I-3-dehydroquinate-dehydratase
MTHVEVVATIAPQLSIEETLIQKINHRIDAIDVLELRIDQIENVTVDQVAEMITKLKVMQDSFKLLVTYRTKLQGGYGQFTNDSYLNLISDLANINGIDMIDIEWQADIDIEKHQRIITHLQQYNKEVVISHHNFESTPPLDELQFIFFKMQKFNPEYVKLAVMPHNKNDVLNLLQAMSTFSDTMDCKVVGISMSKLGLISRTAQGVFGGALTYGCIGEPQAPGQIDVTDLKAQVTLY
>NZ_CP047813.1|WP_043044653.1|1151659_1152082_+|organic-hydroperoxide-resistance-protein
MAIHYETKATNVGGRKGHVYTDDRALDIDIVPPAQADGKATNPEQLFAAGYASCFNGAFDLILKQNKVRDAHPEVTLTVRLEDDSDSESPKLSVSIDATIKNVISQEEAEKYLQMAHEFCPYSKATQGNINVDLNVNVAD
>NZ_CP047813.1|WP_000569884.1|1152480_1152975_+|GNAT-family-N-acetyltransferase
MIEIKTLTNNDFNEYKRLVSTVNEEFTQDSHYSQTMTDTLIHDILNQGSPKCIVFGCYENETLIATAALEQIRYVGKEHKSLIKYNFVTNNDKSINSELINFIINYARQNNYESLLTSIVSNNIGAKVFYSALGFDILGFEKNAIKIGNTYFDEHWLFYDLINK
>NZ_CP047813.1|WP_000255561.1|1153129_1153747_+|amino-acid-transporter
MVTAIIHGFILAIGLILPLGAQNVFIFNQGANQPKYRYVLPAIITAGLSDSLLIIIAVVGVSIIIMSLPVLQAIIYIVGLIFLMYMAWTIWHDKPSTDGETQIMSPMKQVSFALSVSLLNPHAILDTIGVIGSSAALYSGSNKIAFTIACISVSWLWFFLLAILGKMVGSIDKTGKLLTIINKISSIIIIIVALMILQKLIQLLF

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Crispr_ID: NZ_CP047813_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047813_6

1183552-1183638

Orphan

Consensus_repeat	Method
TGCAAGTTGGGGTGTGGGCCCCAACATAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP047813_6

>merge|NZ_CP047813|6|1183552-1183638|CRISPRCasFinder
TGCAAGTTGGGGTGTGGGCCCCAACATAGAGAATTTCGAAATGAAATTCTACAGGCAATGCAAGTTGGGGTGTGGGCCCCAACATAG

>NZ_CP047813|6|6|1183552-1183638|CRISPRCasFinder
TGCAAGTTGGGGTGTGGGCCCCAACATAG	AGAATTTCGAAATGAAATTCTACAGGCAA
TGCAAGTTGGGGTGTGGGCCCCAACATAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047813.1\|WP_043044662.1\|1185218_1186121_+\|TIGR01777-family-protein	unknown	unknown	gnl\|CDD\|224015
NZ_CP047813.1\|WP_001260089.1\|1178836_1179598_-\|triose-phosphate-isomerase	unknown	unknown	gnl\|CDD\|234589
NZ_CP047813.1\|WP_000556760.1\|1174785_1175019_-\|preprotein-translocase-subunit-SecG	unknown	unknown	gnl\|CDD\|224233
NZ_CP047813.1\|WP_000785252.1\|1175085_1175544_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047813.1\|WP_000057543.1\|1192251_1193691_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276808
NZ_CP047813.1\|WP_000070826.1\|1183886_1184516_-\|DUF4887-domain-containing-protein	unknown	unknown	gnl\|CDD\|234750
NZ_CP047813.1\|WP_000513305.1\|1194191_1195031_-\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527
NZ_CP047813.1\|WP_043044661.1\|1171523_1173896_-\|ribonuclease-R	unknown	unknown	gnl\|CDD\|273947
NZ_CP047813.1\|WP_000006551.1\|1187523_1188468_-\|DNA-binding-protein-WhiA	unknown	unknown	gnl\|CDD\|273194
NZ_CP047813.1\|WP_000279414.1\|1181048_1182059_-\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|273675
NZ_CP047813.1\|WP_001085505.1\|1177316_1178834_-\|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase	unknown	unknown	gnl\|CDD\|235463
NZ_CP047813.1\|WP_001049165.1\|1186363_1186951_-\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	unknown	unknown	gnl\|CDD\|178955
NZ_CP047813.1\|WP_001121760.1\|1175882_1177187_-\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NZ_CP047813.1\|WP_043044663.1\|1189570_1190482_-\|RNase-adapter-RapZ	unknown	unknown	gnl\|CDD\|224574
NZ_CP047813.1\|WP_001224793.1\|1193698_1194184_-\|acetyltransferase	unknown	unknown	gnl\|CDD\|100053
NZ_CP047813.1\|WP_160186711.1\|1191249_1192185_-\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540
NZ_CP047813.1\|WP_001074749.1\|1179719_1180910_-\|phosphoglycerate-kinase	unknown	unknown	gnl\|CDD\|234613
NZ_CP047813.1\|WP_001248939.1\|1188578_1189574_-\|YvcK-family-protein	unknown	unknown	gnl\|CDD\|211689
NZ_CP047813.1\|WP_001165961.1\|1173929_1174670_-\|prolyl-oligopeptidase-family-serine-peptidase	unknown	unknown	gnl\|CDD\|224561
NZ_CP047813.1\|WP_000654030.1\|1182111_1183125_-\|sugar-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225263

Protein	Function_ID	Function_description	E-value
NZ_CP047813.1\|WP_001260089.1\|1178836_1179598_-\|triose-phosphate-isomerase	gnl\|CDD\|234589	PRK00042, tpiA, triosephosphate isomerase; Provisional.	2.84083e-146
NZ_CP047813.1\|WP_000556760.1\|1174785_1175019_-\|preprotein-translocase-subunit-SecG	gnl\|CDD\|224233	COG1314, SecG, Preprotein translocase subunit SecG [Intracellular trafficking and secretion].	6.41939e-15
NZ_CP047813.1\|WP_043044663.1\|1189570_1190482_-\|RNase-adapter-RapZ	gnl\|CDD\|224574	COG1660, COG1660, Predicted P-loop-containing kinase [General function prediction only].	1.51321e-169
NZ_CP047813.1\|WP_000057543.1\|1192251_1193691_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	4.14043e-06
NZ_CP047813.1\|WP_043044662.1\|1185218_1186121_+\|TIGR01777-family-protein	gnl\|CDD\|224015	COG1090, COG1090, Predicted nucleoside-diphosphate sugar epimerase [General function prediction only].	6.87149e-154
NZ_CP047813.1\|WP_000513305.1\|1194191_1195031_-\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	1.75588e-120
NZ_CP047813.1\|WP_043044661.1\|1171523_1173896_-\|ribonuclease-R	gnl\|CDD\|273947	TIGR02063, Ribonuclease_R, ribonuclease R. This family consists of an exoribonuclease, ribonuclease R, also called VacB. It is one of the eight exoribonucleases reported in E. coli and is broadly distributed throughout the bacteria. In E. coli, double mutants of this protein and polynucleotide phosphorylase are not viable. Scoring between trusted and noise cutoffs to the model are shorter, divergent forms from the Chlamydiae, and divergent forms from the Campylobacterales (including Helicobacter pylori) and Leptospira interrogans. [Transcription, Degradation of RNA].	0
NZ_CP047813.1\|WP_000070826.1\|1183886_1184516_-\|DUF4887-domain-containing-protein	gnl\|CDD\|234750	PRK00409, PRK00409, recombination and DNA strand exchange inhibitor protein; Reviewed.	5.85535e-05
NZ_CP047813.1\|WP_000279414.1\|1181048_1182059_-\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	gnl\|CDD\|273675	TIGR01534, Glyceraldehyde-3-phosphate_dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase, type I. This model represents glyceraldehyde-3-phosphate dehydrogenase (GAPDH), the enzyme responsible for the interconversion of 1,3-diphosphoglycerate and glyceraldehyde-3-phosphate, a central step in glycolysis and gluconeogenesis. Forms exist which utilize NAD (EC 1.2.1.12), NADP (EC 1.2.1.13) or either (1.2.1.59). In some species, NAD- and NADP- utilizing forms exist, generally being responsible for reactions in the anabolic and catabolic directions respectively. Two Pfam models cover the two functional domains of this protein; pfam00044 represents the N-terminal NAD(P)-binding domain and pfam02800 represents the C-terminal catalytic domain. An additional form of gap gene is found in gamma proteobacteria and is responsible for the conversion of erythrose-4-phosphate (E4P) to 4-phospho-erythronate in the biosynthesis of pyridoxine. This pathway of pyridoxine biosynthesis appears to be limited, however, to a relatively small number of bacterial species although it is prevalent among the gamma-proteobacteria. This enzyme is described by TIGR001532. These sequences generally score between trusted and noise to this GAPDH model due to the close evolutionary relationship. There exists the possiblity that some forms of GAPDH may be bifunctional and act on E4P in species which make pyridoxine and via hydroxythreonine and lack a separate E4PDH enzyme (for instance, the GAPDH from Bacillus stearothermophilus has been shown to posess a limited E4PD activity as well as a robust GAPDH activity). There are a great number of sequences in the databases which score between trusted and noise to this model, nearly all of them due to fragmentary sequences. It seems that study of this gene has been carried out in many species utilizing PCR probes which exclude the extreme ends of the consenses used to define this model. The noise level is set relative not to E4PD, but the next closest outliers, the class II GAPDH's (found in archaea, TIGR01546) and aspartate semialdehyde dehydrogenase (ASADH, TIGR01296) both of which have highest-scoring hits around -225 to the prior model. [Energy metabolism, Glycolysis/gluconeogenesis].	0
NZ_CP047813.1\|WP_001085505.1\|1177316_1178834_-\|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase	gnl\|CDD\|235463	PRK05434, PRK05434, 2,3-bisphosphoglycerate-independent phosphoglycerate mutase.	0
NZ_CP047813.1\|WP_001049165.1\|1186363_1186951_-\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	4.59321e-148
NZ_CP047813.1\|WP_001121760.1\|1175882_1177187_-\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NZ_CP047813.1\|WP_000006551.1\|1187523_1188468_-\|DNA-binding-protein-WhiA	gnl\|CDD\|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	7.40812e-153
NZ_CP047813.1\|WP_001224793.1\|1193698_1194184_-\|acetyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	4.85181e-30
NZ_CP047813.1\|WP_160186711.1\|1191249_1192185_-\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	3.05741e-153
NZ_CP047813.1\|WP_001074749.1\|1179719_1180910_-\|phosphoglycerate-kinase	gnl\|CDD\|234613	PRK00073, pgk, phosphoglycerate kinase; Provisional.	0
NZ_CP047813.1\|WP_001248939.1\|1188578_1189574_-\|YvcK-family-protein	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	5.06652e-172
NZ_CP047813.1\|WP_001165961.1\|1173929_1174670_-\|prolyl-oligopeptidase-family-serine-peptidase	gnl\|CDD\|224561	COG1647, COG1647, Esterase/lipase [General function prediction only].	1.04183e-130
NZ_CP047813.1\|WP_000654030.1\|1182111_1183125_-\|sugar-binding-transcriptional-regulator	gnl\|CDD\|225263	COG2390, DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription].	1.39665e-92

>NZ_CP047813.1|WP_000654030.1|1182111_1183125_-|sugar-binding-transcriptional-regulator
MKDLLQAQQKLIPDLIDKMYKRFSILTTISKNQPVGRRSLSEHMDMTERVLRSETDMLKKQDLIKVKPTGMEITAEGEQLISQLKGYFDIYADDNRLSEGIKNKFQIKEVHVVPGDADNSQSVKTELGRQAGQLLEGILQEDAIVAVTGGSTMACVSEAIHLLPYNVFFVPARGGLGENVVFQANTIAASMAQQAGGYYTTMYVPDNVSETTYNTLLLEPSVINTLDKIKQANVILHGIGDALKMAHRRQSPEKVIEQLQHHQAVGEAFGYYFDTQGQIVHKVKTIGLQLEDLESKDFIFAVAGGKSKGEAIKAYLTIAPKNTVLITDEAAAKIILE
>NZ_CP047813.1|WP_000279414.1|1181048_1182059_-|type-I-glyceraldehyde-3-phosphate-dehydrogenase
MAVKVAINGFGRIGRLAFRRIQEVEGLEVVAVNDLTDDDMLAHLLKYDTMQGRFTGEVEVVDGGFRVNGKEVKSFSEPDASKLPWKDLNIDVVLECTGFYTDKDKAQAHIEAGAKKVLISAPATGDLKTIVFNTNHQELDGSETVVSGASCTTNSLAPVAKVLNDDFGLVEGLMTTIHAYTGDQNTQDAPHRKGDKRRARAAAENIIPNSTGAAKAIGKVIPEIDGKLDGGAQRVPVATGSLTELTVVLEKQDVTVEQVNEAMKNASNESFGYTEDEIVSSDVVGMTYGSLFDATQTRVMSVGDRQLVKVAAWYDNEMSYTAQLVRTLAYLAELSK
>NZ_CP047813.1|WP_001074749.1|1179719_1180910_-|phosphoglycerate-kinase
MAKKIVSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESDKAKLTLRPVAEDLSKKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYEDLDGKKESKNDPELGKYWASLGDVFVNDAFGTAHREHASNVGISTHLETAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKEIGISLLEEDKIDFAKDLLEKHGDKIVLPVDTKVAKEFSNDAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVVWNGPMGVFEFSNFAQGTIGVCKAIANLKDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKAINNK
>NZ_CP047813.1|WP_001260089.1|1178836_1179598_-|triose-phosphate-isomerase
MRTPIIAGNWKMNKTVQEAKDFVNALPTLPDSKEVESVICAPAIQLDALTTAVKEGKAQGLEIGAQNTYFEDNGAFTGETSPVALADLGVKYVVIGHSERRELFHETDEEINKKAHAIFKHGMTPIICVGETDEERESGKANDVVGEQVKKAVAGLSEDQLKSVVIAYEPIWAIGTGKSSTSEDANEMCAFVRQTIADLSSKEVSEATRIQYGGSVKPNNIKEYMAQTDIDGALVGGASLKVEDFVQLLEGAK
>NZ_CP047813.1|WP_001085505.1|1177316_1178834_-|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase
MAKKPTALIILDGFANRESEHGNAVKLANKPNFDRYYNKYPTTQIEASGLDVGLPEGQMGNSEVGHMNIGAGRIVYQSLTRINKSIEDGDFFENDVLNNAIAHVNSHDSALHIFGLLSDGGVHSHYKHLFALLELAKKQGVEKVYVHAFLDGRDVDQKSALKYIEETEAKFNELGIGQFASVSGRYYAMDRDKRWEREEKAYNAIRNFDAPTYATAKEGVEASYNEGLTDEFVVPFIVENQNDGVNDGDAVIFYNFRPDRAAQLSEIFANRAFEGFKVEQVKDLFYATFTKYNDNIDAAIVFEKVDLNNTIGEIAQNNNLTQLRIAETEKYPHVTYFMSGGRNEEFKGERRRLIDSPKVATYDLKPEMSAYEVKDALLEELNKGDLDLIILNFANPDMVGHSGMLEPTIKAIEAVDECLGEVVDKILDMDGYAIITADHGNSDQVLTDDDQPMTTHTTNPVPVIVTKEGVTLRETGRLGDLAPTLLDLLNVEQPEDMTGESLIKH
>NZ_CP047813.1|WP_001121760.1|1175882_1177187_-|phosphopyruvate-hydratase
MPIITDVYAREVLDSRGNPTVEVEVLTESGAFGRALVPSGASTGEHEAVELRDGDKSRYLGKGVTKAVENVNEIIAPEIIEGEFSVLDQVSIDKMMIALDGTPNKGKLGANAILGVSIAVARAAADLLGQPLYKYLGGFNGKQLPVPMMNIVNGGSHSDAPIAFQEFMILPVGATTFKESLRWGTEIFHNLKSILSKRGLETAVGDEGGFAPKFEGTEDAVETIIQAIEAAGYKPGEEVFLGFDCASSEFYENGVYDYSKFEGEHGAKRTAAEQVDYLEQLVDKYPIITIEDGMDENDWDGWKQLTERIGDRVQLVGDDLFVTNTEILAKGIENGIGNSILIKVNQIGTLTETFDAIEMAQKAGYTAVVSHRSGETEDTTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDELFETAKYDGIKSFYNLDK
>NZ_CP047813.1|WP_000785252.1|1175085_1175544_-|hypothetical-protein
MADRTNKEIKTGRFIATASIVFSILLIIHYFVSLDNATAKALLNLTNQNTSDKAIDYILNSFRFTGIMYILAYLAGFITFWNRHTYVWWFMFAVYVSNSLFTLINLSITIQAIKAAHGAYLTLPILIVIIGSVALAIYMLVVSIKRKSTFNR
>NZ_CP047813.1|WP_000556760.1|1174785_1175019_-|preprotein-translocase-subunit-SecG
MHTFLIVLLIIDCIALITVVLLQEGKSSGLSGAISGGAEQLFGKQKQRGVDLFLNRLTIILSILFFVLMICISYLGM
>NZ_CP047813.1|WP_001165961.1|1173929_1174670_-|prolyl-oligopeptidase-family-serine-peptidase
MQIKLPKPFFFEEGKRAVLLLHGFTGNSSDVRQLGRFLQKKGYTSYAPQYEGHAAPPEEILKSSPFVWFKDALDGYDYLVEQGYDEIVVAGLSLGGDFALKLSLNRDVKGIVTMCAPMGGKTEGTIYEGFLEYARNFKKYEGKDQETIDNEMDHFKPTETLKELSEALDTIKEQVDEVLDPILVIQAENDNMIDPQSANYIYDHVDSDDKNIKWYSESGHVITIDKEKEQVFEDIYQFLESLDWSE
>NZ_CP047813.1|WP_043044661.1|1171523_1173896_-|ribonuclease-R
MNLKQSIEEIINQPEYEPMSVSDFQDALGLSSADSFRDLIKVLVELEQSGLIERTKTDRYQKKHSSRGQSKLIKGTLSQNKKGFAFLRPEDEDMEDIFIPPTKINRALDGDTVIVEIHQSKGEHKGKIEGEVKSIEKHSVTQVVGTYSEARHFGFVIPDDKRIMQDIFIPKGQSLGAVDGHKVLVQITKYADGSDNPEGHISAILGHKNDPGVDILSIIYQHGIEIEFPDVVLQEAEAVPDHIENTEIKGRHDLRDELTITIDGADAKDLDDAISVKKLANGNTQLTVSIADVSYYVTEDSALDKEAYDRATSVYLVDRVIPMIPHRLSNGICSLNPHVDRLTLSCRMEIDASGRVVKHEIFDSVIHSDYRMTYDAVNQIITEKDPNIREQYKEITPMLDLAQDLSNRLIQMRKRRGEIDFDISEAKVLVNEDGIPTDVQLRQRGEGERLIESFMLIANETVAEHFSKLDVPFIYRVHEQPKSDRLRQFFDFITNFGIMIKGTGEDIHPTTLQKVQEEVEGRPEQMVISTMMLRSMQQAHYDDVNLGHFGLSAEYYTHFTSPIRRYPDLTVHRLIRKYLIEKSMDNKEVKRWEDKLPELAEHTSKRERRAIEAERDTDELKKAEYMIQHIGDEFEGIVSSVANFGMFIELPNTIEGMVHIANMTDDYYRFEERQMALIGERQAKVFRIGDTVKVKVTHVDVDERLIDFQIVGMPLPKNDRSQRPARGKTIQAKTRGKSLDKSKSDDKGRKKKGSQRKGKNERKNDKSGNSKHKPFYKDKSVKKKARRKKK
>NZ_CP047813.1|WP_000070826.1|1183886_1184516_-|DUF4887-domain-containing-protein
MSNQNYDYNKNEDGSKKKMSTTAKVVSIATVLLLLGGLVFAIFAYVDHSNKAKERMLNEQKQEQKEKRQKENAEKERKKKQQEEKEQNELDSQANQYQQLPQQNQYQYVPPQQQAPTKQRPAKEENDDKASKDESKDKDDKASQDKSDDNQKKTDDNKQPAQPKPQPQQPTPKPNNNQQNNQSNQQAKPQAPQQNSQSTTNKQNNANDK
>NZ_CP047813.1|WP_043044662.1|1185218_1186121_+|TIGR01777-family-protein
MKQYLITGGTGMVGSQLVNEIKKSDSHITILTRHDQISNDKKISYVNWAKSGWEHKVPQNIDVVINLAGATLNKRWTPEYKQTLMLSRIQSTQALYELFKSRNKAPKVLFNASATGYYPPDLFMSYTEVYKTLPFDFLSDIVYQWERFAQQFEQLGTRVVIGRFGMILSNEGGALQTMKLPYEYYIGGKLGSGQQWYSWIHINDLIQAILFLINNESASGPFNLTAPIPERQNLFGYTLARAMHKPHETWAPSLAMRLILGQMSTVVLDTQKVLPNKIQALGFQFKYSNLKMALEDLIKE
>NZ_CP047813.1|WP_001049165.1|1186363_1186951_-|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
>NZ_CP047813.1|WP_000006551.1|1187523_1188468_-|DNA-binding-protein-WhiA
MSFASEMKNELTRIDVDEMNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGILKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGLTKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLKELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL
>NZ_CP047813.1|WP_001248939.1|1188578_1189574_-|YvcK-family-protein
MRQIKVVLIGGGTGLSVMARGLREFPIDITAIVTVADNGGSTGKIRDEMDIPAPGDIRNVIAALSDSESVLSQLFQYRFEENQISGHSLGNLLIAGMTNITNDFGHAIKALSKILNIKGRVIPSTNTSVQLNAVMEDGEIVFGETNIPKKHKKIDRVFLEPNDVQPMEEAIDALREADLIVLGPGSLYTSVISNLCVNGISDALIHSDAPKLYVSNVMTQPGETDGYSVKDHIDAIHRQAGQPFIDYVICSTQTFNAQVLKKYEEKHSKPVEVNKAELEKESINVKTSSNLVEISENHLVRHNTKVLSTMIYDIALELISTIPFVPSDKRK
>NZ_CP047813.1|WP_043044663.1|1189570_1190482_-|RNase-adapter-RapZ
MDNNEKEKSKSELLVVTGLSGAGKSLVIQCLEDMGYFCVDNLPPVLLPKFVELMEQGNPSLRKVAIAIDLRGKELFNSLVAVVDKVKSESDVIIDVMFLEASTEKLISRYKETRRAHPLMEQGKRSLINAINDEREHLSQIRSIANFVIDTTKLSPKELKDRIRRYYEDEEFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVVDLRPLTGLDKDVYNYVMKWKETEIFFEKLTDLLDFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAERLGNYLNEVFEYNVYVHHRDAHIESGEKK
>NZ_CP047813.1|WP_160186711.1|1191249_1192185_-|thioredoxin-disulfide-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKLTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA
>NZ_CP047813.1|WP_000057543.1|1192251_1193691_-|tetratricopeptide-repeat-protein
MAQKNNNVIPMTFDDAFYRKMAKQKFKQREYKRAAEYFEKVLELSPDDLEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDTAKALYEALLQEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYQNELFVSENDLMVAWINQGELIIAEKVDLTDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>NZ_CP047813.1|WP_001224793.1|1193698_1194184_-|acetyltransferase
MRKFLSKTHHHTNPLWRVYRLVKFSKVFKNVIIIEFSKFIPSMVLKRHIYKQLLNINIGNQSSIAYKVMLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>NZ_CP047813.1|WP_000513305.1|1194191_1195031_-|prolipoprotein-diacylglyceryl-transferase
MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYAENPSEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGPVSRAFLEQLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTKKVK

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Crispr_ID: NZ_CP047813_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047813_7

1190759-1190849

Orphan

Consensus_repeat	Method
CAATGCAAGTTGGGGTGTGGGCCCCAACACAGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP047813_7

>merge|NZ_CP047813|7|1190759-1190849|CRISPRCasFinder
CAATGCAAGTTGGGGTGTGGGCCCCAACACAGAGAATTTCGAAAAGAAATTCTACAGGCAATGCGAGTTGGGGTGTGGGCCCCAACACAGA

>NZ_CP047813|7|7|1190759-1190849|CRISPRCasFinder
CAATGCAAGTTGGGGTGTGGGCCCCAACACAGA	GAATTTCGAAAAGAAATTCTACAGG
CAATGCGAGTTGGGGTGTGGGCCCCAACACAGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047813.1\|WP_000538141.1\|1201971_1202622_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|378993
NZ_CP047813.1\|WP_001260089.1\|1178836_1179598_-\|triose-phosphate-isomerase	unknown	unknown	gnl\|CDD\|234589
NZ_CP047813.1\|WP_043044664.1\|1196630_1199477_-\|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl\|CDD\|234734
NZ_CP047813.1\|WP_000958224.1\|1195036_1195969_-\|HPr-kinase/phosphorylase	unknown	unknown	gnl\|CDD\|235459
NZ_CP047813.1\|WP_000057543.1\|1192251_1193691_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276808
NZ_CP047813.1\|WP_000070826.1\|1183886_1184516_-\|DUF4887-domain-containing-protein	unknown	unknown	gnl\|CDD\|234750
NZ_CP047813.1\|WP_000513305.1\|1194191_1195031_-\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527
NZ_CP047813.1\|WP_043044666.1\|1202795_1203635_-\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_CP047813.1\|WP_043044663.1\|1189570_1190482_-\|RNase-adapter-RapZ	unknown	unknown	gnl\|CDD\|224574
NZ_CP047813.1\|WP_000279414.1\|1181048_1182059_-\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|273675
NZ_CP047813.1\|WP_043044662.1\|1185218_1186121_+\|TIGR01777-family-protein	unknown	unknown	gnl\|CDD\|224015
NZ_CP047813.1\|WP_001049165.1\|1186363_1186951_-\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	unknown	unknown	gnl\|CDD\|178955
NZ_CP047813.1\|WP_001248939.1\|1188578_1189574_-\|YvcK-family-protein	unknown	unknown	gnl\|CDD\|211689
NZ_CP047813.1\|WP_000006551.1\|1187523_1188468_-\|DNA-binding-protein-WhiA	unknown	unknown	gnl\|CDD\|273194
NZ_CP047813.1\|WP_001224793.1\|1193698_1194184_-\|acetyltransferase	unknown	unknown	gnl\|CDD\|100053
NZ_CP047813.1\|WP_000229253.1\|1199484_1201470_-\|excinuclease-ABC-subunit-UvrB	unknown	unknown	gnl\|CDD\|235395
NZ_CP047813.1\|WP_001074749.1\|1179719_1180910_-\|phosphoglycerate-kinase	unknown	unknown	gnl\|CDD\|234613
NZ_CP047813.1\|WP_160186711.1\|1191249_1192185_-\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540
NZ_CP047813.1\|WP_043044665.1\|1201738_1201975_-\|CsbA-family-protein	unknown	unknown	gnl\|CDD\|227234
NZ_CP047813.1\|WP_000654030.1\|1182111_1183125_-\|sugar-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225263

Protein	Function_ID	Function_description	E-value
NZ_CP047813.1\|WP_000538141.1\|1201971_1202622_-\|HD-domain-containing-protein	gnl\|CDD\|378993	pfam12917, HD_2, HD containing hydrolase-like enzyme. This is a family of bacterial and archaeal hydrolases.	6.51021e-58
NZ_CP047813.1\|WP_001260089.1\|1178836_1179598_-\|triose-phosphate-isomerase	gnl\|CDD\|234589	PRK00042, tpiA, triosephosphate isomerase; Provisional.	2.84083e-146
NZ_CP047813.1\|WP_043044664.1\|1196630_1199477_-\|excinuclease-ABC-subunit-UvrA	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
NZ_CP047813.1\|WP_000958224.1\|1195036_1195969_-\|HPr-kinase/phosphorylase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.22623e-170
NZ_CP047813.1\|WP_000057543.1\|1192251_1193691_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	4.14043e-06
NZ_CP047813.1\|WP_000070826.1\|1183886_1184516_-\|DUF4887-domain-containing-protein	gnl\|CDD\|234750	PRK00409, PRK00409, recombination and DNA strand exchange inhibitor protein; Reviewed.	5.85535e-05
NZ_CP047813.1\|WP_000513305.1\|1194191_1195031_-\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	1.75588e-120
NZ_CP047813.1\|WP_043044666.1\|1202795_1203635_-\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.70553e-42
NZ_CP047813.1\|WP_043044663.1\|1189570_1190482_-\|RNase-adapter-RapZ	gnl\|CDD\|224574	COG1660, COG1660, Predicted P-loop-containing kinase [General function prediction only].	1.51321e-169
NZ_CP047813.1\|WP_000279414.1\|1181048_1182059_-\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	gnl\|CDD\|273675	TIGR01534, Glyceraldehyde-3-phosphate_dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase, type I. This model represents glyceraldehyde-3-phosphate dehydrogenase (GAPDH), the enzyme responsible for the interconversion of 1,3-diphosphoglycerate and glyceraldehyde-3-phosphate, a central step in glycolysis and gluconeogenesis. Forms exist which utilize NAD (EC 1.2.1.12), NADP (EC 1.2.1.13) or either (1.2.1.59). In some species, NAD- and NADP- utilizing forms exist, generally being responsible for reactions in the anabolic and catabolic directions respectively. Two Pfam models cover the two functional domains of this protein; pfam00044 represents the N-terminal NAD(P)-binding domain and pfam02800 represents the C-terminal catalytic domain. An additional form of gap gene is found in gamma proteobacteria and is responsible for the conversion of erythrose-4-phosphate (E4P) to 4-phospho-erythronate in the biosynthesis of pyridoxine. This pathway of pyridoxine biosynthesis appears to be limited, however, to a relatively small number of bacterial species although it is prevalent among the gamma-proteobacteria. This enzyme is described by TIGR001532. These sequences generally score between trusted and noise to this GAPDH model due to the close evolutionary relationship. There exists the possiblity that some forms of GAPDH may be bifunctional and act on E4P in species which make pyridoxine and via hydroxythreonine and lack a separate E4PDH enzyme (for instance, the GAPDH from Bacillus stearothermophilus has been shown to posess a limited E4PD activity as well as a robust GAPDH activity). There are a great number of sequences in the databases which score between trusted and noise to this model, nearly all of them due to fragmentary sequences. It seems that study of this gene has been carried out in many species utilizing PCR probes which exclude the extreme ends of the consenses used to define this model. The noise level is set relative not to E4PD, but the next closest outliers, the class II GAPDH's (found in archaea, TIGR01546) and aspartate semialdehyde dehydrogenase (ASADH, TIGR01296) both of which have highest-scoring hits around -225 to the prior model. [Energy metabolism, Glycolysis/gluconeogenesis].	0
NZ_CP047813.1\|WP_043044662.1\|1185218_1186121_+\|TIGR01777-family-protein	gnl\|CDD\|224015	COG1090, COG1090, Predicted nucleoside-diphosphate sugar epimerase [General function prediction only].	6.87149e-154
NZ_CP047813.1\|WP_001049165.1\|1186363_1186951_-\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	4.59321e-148
NZ_CP047813.1\|WP_001248939.1\|1188578_1189574_-\|YvcK-family-protein	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	5.06652e-172
NZ_CP047813.1\|WP_000006551.1\|1187523_1188468_-\|DNA-binding-protein-WhiA	gnl\|CDD\|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	7.40812e-153
NZ_CP047813.1\|WP_001224793.1\|1193698_1194184_-\|acetyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	4.85181e-30
NZ_CP047813.1\|WP_000229253.1\|1199484_1201470_-\|excinuclease-ABC-subunit-UvrB	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
NZ_CP047813.1\|WP_001074749.1\|1179719_1180910_-\|phosphoglycerate-kinase	gnl\|CDD\|234613	PRK00073, pgk, phosphoglycerate kinase; Provisional.	0
NZ_CP047813.1\|WP_160186711.1\|1191249_1192185_-\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	3.05741e-153
NZ_CP047813.1\|WP_043044665.1\|1201738_1201975_-\|CsbA-family-protein	gnl\|CDD\|227234	COG4897, CsbA, Uncharacterized protein conserved in bacteria [Function unknown].	9.29167e-34
NZ_CP047813.1\|WP_000654030.1\|1182111_1183125_-\|sugar-binding-transcriptional-regulator	gnl\|CDD\|225263	COG2390, DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription].	1.39665e-92

>NZ_CP047813.1|WP_043044663.1|1189570_1190482_-|RNase-adapter-RapZ
MDNNEKEKSKSELLVVTGLSGAGKSLVIQCLEDMGYFCVDNLPPVLLPKFVELMEQGNPSLRKVAIAIDLRGKELFNSLVAVVDKVKSESDVIIDVMFLEASTEKLISRYKETRRAHPLMEQGKRSLINAINDEREHLSQIRSIANFVIDTTKLSPKELKDRIRRYYEDEEFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVVDLRPLTGLDKDVYNYVMKWKETEIFFEKLTDLLDFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAERLGNYLNEVFEYNVYVHHRDAHIESGEKK
>NZ_CP047813.1|WP_001248939.1|1188578_1189574_-|YvcK-family-protein
MRQIKVVLIGGGTGLSVMARGLREFPIDITAIVTVADNGGSTGKIRDEMDIPAPGDIRNVIAALSDSESVLSQLFQYRFEENQISGHSLGNLLIAGMTNITNDFGHAIKALSKILNIKGRVIPSTNTSVQLNAVMEDGEIVFGETNIPKKHKKIDRVFLEPNDVQPMEEAIDALREADLIVLGPGSLYTSVISNLCVNGISDALIHSDAPKLYVSNVMTQPGETDGYSVKDHIDAIHRQAGQPFIDYVICSTQTFNAQVLKKYEEKHSKPVEVNKAELEKESINVKTSSNLVEISENHLVRHNTKVLSTMIYDIALELISTIPFVPSDKRK
>NZ_CP047813.1|WP_000006551.1|1187523_1188468_-|DNA-binding-protein-WhiA
MSFASEMKNELTRIDVDEMNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGILKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGLTKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLKELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL
>NZ_CP047813.1|WP_001049165.1|1186363_1186951_-|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
>NZ_CP047813.1|WP_043044662.1|1185218_1186121_+|TIGR01777-family-protein
MKQYLITGGTGMVGSQLVNEIKKSDSHITILTRHDQISNDKKISYVNWAKSGWEHKVPQNIDVVINLAGATLNKRWTPEYKQTLMLSRIQSTQALYELFKSRNKAPKVLFNASATGYYPPDLFMSYTEVYKTLPFDFLSDIVYQWERFAQQFEQLGTRVVIGRFGMILSNEGGALQTMKLPYEYYIGGKLGSGQQWYSWIHINDLIQAILFLINNESASGPFNLTAPIPERQNLFGYTLARAMHKPHETWAPSLAMRLILGQMSTVVLDTQKVLPNKIQALGFQFKYSNLKMALEDLIKE
>NZ_CP047813.1|WP_000070826.1|1183886_1184516_-|DUF4887-domain-containing-protein
MSNQNYDYNKNEDGSKKKMSTTAKVVSIATVLLLLGGLVFAIFAYVDHSNKAKERMLNEQKQEQKEKRQKENAEKERKKKQQEEKEQNELDSQANQYQQLPQQNQYQYVPPQQQAPTKQRPAKEENDDKASKDESKDKDDKASQDKSDDNQKKTDDNKQPAQPKPQPQQPTPKPNNNQQNNQSNQQAKPQAPQQNSQSTTNKQNNANDK
>NZ_CP047813.1|WP_000654030.1|1182111_1183125_-|sugar-binding-transcriptional-regulator
MKDLLQAQQKLIPDLIDKMYKRFSILTTISKNQPVGRRSLSEHMDMTERVLRSETDMLKKQDLIKVKPTGMEITAEGEQLISQLKGYFDIYADDNRLSEGIKNKFQIKEVHVVPGDADNSQSVKTELGRQAGQLLEGILQEDAIVAVTGGSTMACVSEAIHLLPYNVFFVPARGGLGENVVFQANTIAASMAQQAGGYYTTMYVPDNVSETTYNTLLLEPSVINTLDKIKQANVILHGIGDALKMAHRRQSPEKVIEQLQHHQAVGEAFGYYFDTQGQIVHKVKTIGLQLEDLESKDFIFAVAGGKSKGEAIKAYLTIAPKNTVLITDEAAAKIILE
>NZ_CP047813.1|WP_000279414.1|1181048_1182059_-|type-I-glyceraldehyde-3-phosphate-dehydrogenase
MAVKVAINGFGRIGRLAFRRIQEVEGLEVVAVNDLTDDDMLAHLLKYDTMQGRFTGEVEVVDGGFRVNGKEVKSFSEPDASKLPWKDLNIDVVLECTGFYTDKDKAQAHIEAGAKKVLISAPATGDLKTIVFNTNHQELDGSETVVSGASCTTNSLAPVAKVLNDDFGLVEGLMTTIHAYTGDQNTQDAPHRKGDKRRARAAAENIIPNSTGAAKAIGKVIPEIDGKLDGGAQRVPVATGSLTELTVVLEKQDVTVEQVNEAMKNASNESFGYTEDEIVSSDVVGMTYGSLFDATQTRVMSVGDRQLVKVAAWYDNEMSYTAQLVRTLAYLAELSK
>NZ_CP047813.1|WP_001074749.1|1179719_1180910_-|phosphoglycerate-kinase
MAKKIVSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESDKAKLTLRPVAEDLSKKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYEDLDGKKESKNDPELGKYWASLGDVFVNDAFGTAHREHASNVGISTHLETAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKEIGISLLEEDKIDFAKDLLEKHGDKIVLPVDTKVAKEFSNDAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVVWNGPMGVFEFSNFAQGTIGVCKAIANLKDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKAINNK
>NZ_CP047813.1|WP_001260089.1|1178836_1179598_-|triose-phosphate-isomerase
MRTPIIAGNWKMNKTVQEAKDFVNALPTLPDSKEVESVICAPAIQLDALTTAVKEGKAQGLEIGAQNTYFEDNGAFTGETSPVALADLGVKYVVIGHSERRELFHETDEEINKKAHAIFKHGMTPIICVGETDEERESGKANDVVGEQVKKAVAGLSEDQLKSVVIAYEPIWAIGTGKSSTSEDANEMCAFVRQTIADLSSKEVSEATRIQYGGSVKPNNIKEYMAQTDIDGALVGGASLKVEDFVQLLEGAK
>NZ_CP047813.1|WP_160186711.1|1191249_1192185_-|thioredoxin-disulfide-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKLTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA
>NZ_CP047813.1|WP_000057543.1|1192251_1193691_-|tetratricopeptide-repeat-protein
MAQKNNNVIPMTFDDAFYRKMAKQKFKQREYKRAAEYFEKVLELSPDDLEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDTAKALYEALLQEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYQNELFVSENDLMVAWINQGELIIAEKVDLTDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>NZ_CP047813.1|WP_001224793.1|1193698_1194184_-|acetyltransferase
MRKFLSKTHHHTNPLWRVYRLVKFSKVFKNVIIIEFSKFIPSMVLKRHIYKQLLNINIGNQSSIAYKVMLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>NZ_CP047813.1|WP_000513305.1|1194191_1195031_-|prolipoprotein-diacylglyceryl-transferase
MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYAENPSEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGPVSRAFLEQLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTKKVK
>NZ_CP047813.1|WP_000958224.1|1195036_1195969_-|HPr-kinase/phosphorylase
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
>NZ_CP047813.1|WP_043044664.1|1196630_1199477_-|excinuclease-ABC-subunit-UvrA
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNINLSEQDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIEVPEYRRPASNRKISIRGARSNNLKGVDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
>NZ_CP047813.1|WP_000229253.1|1199484_1201470_-|excinuclease-ABC-subunit-UvrB
MVEHYPFKIHSDFEPQGDQPQAIKEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
>NZ_CP047813.1|WP_043044665.1|1201738_1201975_-|CsbA-family-protein
MIWYFSAAFFPCILVVLFSVITRSKWVGTILTLILIGASIYKEYFHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR
>NZ_CP047813.1|WP_000538141.1|1201971_1202622_-|HD-domain-containing-protein
MGVHQYFKRLSDMERLIRLPGKFKYFEHNVAAHSFKVTKIAQYLATVEEYHGRKINWKSLYEKALNHDFAEVFTGDIKTPVKYASSELKKLFSQVEEEMVETFIEEEIPLQYRDVYKQRLQEGKDDSLEGQILSVADKIDLLYETFGEIQKRNPEELFFEIYEMSLETIIQFDHLASVQDFINNIIPEMLTENFIPRTELRETTMNILNKRKEENE
>NZ_CP047813.1|WP_043044666.1|1202795_1203635_-|CHAP-domain-containing-protein
MKKSLTVTVSSVLAFLALNNAAHAQQHGTQVKTPVQHNYVSNVQVQTQSPTTYTVVAGDSLYKIALEHHLTLNQLYSYNPGVTPLIFPGDVISLVPQNKVKQTKAVKSPVRKASQAKKVVKQPVQQASKKVVVKQAPKQAVAKTVNVAYKPAQVQKSVPTVPVAHNYNKSVANRGNLYAYGNCTYYAFDRRAQLGRSIGSLWGNANNWNYAAKVAGFKVDKTPEVGAIFQTAAGPYGHVGVVESVNPNGTITVSEMNYAGFNVKSSRTILNPGKYNYIH

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Crispr_ID: NZ_CP047813_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047813_8

1353210-1353503

Orphan

Consensus_repeat	Method
CTTTAGCGATTAGAGGCTTTTATGCAGTTGTGCCTTAGNATC	CRT

4 spacers

The CRISPR arrays of NZ_CP047813_8

>merge|NZ_CP047813|8|1353210-1353503|CRT
CTTTAGCGATTAGAGGCTTTTATGCAGTTGTGCCTTAGTATCCAACTGCGTTCCTCTTCACCTTTAGCGATTAGAGGCTTTTATGCAGTTGTGCCTTAGCATCAAACTGCGTTCCTCTTCACCTTTAGCGATTAGAGGGATTTATGCAGTTGTGCCTTAGCATCAAATTGCGTTCCTTTAATCTTCTTGAGCTTTAGCGATTAGAGGCTTTTATGCAGTTGTGCCTTAGCATCCAACTGCGTTCCTCTTCACCTTTAGCGATTAGAGGCTTTTATGCAGTTGCTGCACAAACAA

>NZ_CP047813|8|1|1353210-1353503|CRT
CTTTAGCGATTAGAGGCTTTTATGCAGTTGTGCCTTAGTATC	CAACTGCGTTCCTCTTCAC
CTTTAGCGATTAGAGGCTTTTATGCAGTTGTGCCTTAGCATC	AAACTGCGTTCCTCTTCAC
CTTTAGCGATTAGAGGGATTTATGCAGTTGTGCCTTAGCATC	AAATTGCGTTCCTTTAATCTTCTTGAG
CTTTAGCGATTAGAGGCTTTTATGCAGTTGTGCCTTAGCATC	CAACTGCGTTCCTCTTCAC
CTTTAGCGATTAGAGGCTTTTATGCAGTTGCTGCACAAACAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047813.1\|WP_000365354.1\|1350417_1351137_-\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|223943
NZ_CP047813.1\|WP_072399260.1\|1352289_1353117_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238563
NZ_CP047813.1\|WP_000633782.1\|1360976_1361513_-\|flavodoxin-family-protein	unknown	unknown	gnl\|CDD\|223728
NZ_CP047813.1\|WP_043044703.1\|1354588_1356250_-\|arginine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234964
NZ_CP047813.1\|WP_001788287.1\|1358447_1358969_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378039
NZ_CP047813.1\|WP_000477504.1\|1360331_1360808_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP047813.1\|WP_001819741.1\|1356246_1356630_-\|DUF1934-family-protein	unknown	unknown	gnl\|CDD\|226896
NZ_CP047813.1\|WP_000169042.1\|1344237_1344462_+\|DUF2922-domain-containing-protein	unknown	unknown	gnl\|CDD\|378571
NZ_CP047813.1\|WP_043044698.1\|1344656_1345586_+\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|225778
NZ_CP047813.1\|WP_000808896.1\|1362013_1362952_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381309
NZ_CP047813.1\|WP_001018677.1\|1346533_1346908_+\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|130944
NZ_CP047813.1\|WP_001222133.1\|1348113_1348830_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047813.1\|WP_000362978.1\|1349633_1350434_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP047813.1\|WP_000901749.1\|1353617_1354253_-\|endonuclease-III-domain-containing-protein	unknown	unknown	gnl\|CDD\|225140
NZ_CP047813.1\|WP_001790232.1\|1351191_1352142_-\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376439
NZ_CP047813.1\|WP_070005418.1\|1347156_1347945_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP047813.1\|WP_000923049.1\|1363221_1363848_-\|DUF443-domain-containing-protein	unknown	unknown	gnl\|CDD\|335700
NZ_CP047813.1\|WP_000735551.1\|1348991_1349498_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047813.1\|WP_000180230.1\|1358996_1360292_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224004
NZ_CP047813.1\|WP_001200748.1\|1356938_1357949_-\|alcohol-dehydrogenase-AdhP	unknown	unknown	gnl\|CDD\|181842

Protein	Function_ID	Function_description	E-value
NZ_CP047813.1\|WP_000365354.1\|1350417_1351137_-\|HAD-family-hydrolase	gnl\|CDD\|223943	COG1011, COG1011, Predicted hydrolase (HAD superfamily) [General function prediction only].	3.6864e-38
NZ_CP047813.1\|WP_072399260.1\|1352289_1353117_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|238563	cd01143, YvrC, Periplasmic binding protein YvrC. These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria and archaea. They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains.	5.87343e-72
NZ_CP047813.1\|WP_000633782.1\|1360976_1361513_-\|flavodoxin-family-protein	gnl\|CDD\|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	3.16348e-26
NZ_CP047813.1\|WP_043044703.1\|1354588_1356250_-\|arginine--tRNA-ligase	gnl\|CDD\|234964	PRK01611, argS, arginyl-tRNA synthetase; Reviewed.	0
NZ_CP047813.1\|WP_001788287.1\|1358447_1358969_-\|hypothetical-protein	gnl\|CDD\|378039	pfam08741, YwhD, YwhD family. This family of proteins are currently uncharacterized. They are around 170 amino acids in length.	8.7406e-98
NZ_CP047813.1\|WP_000477504.1\|1360331_1360808_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.13315e-11
NZ_CP047813.1\|WP_001819741.1\|1356246_1356630_-\|DUF1934-family-protein	gnl\|CDD\|226896	COG4506, COG4506, Uncharacterized protein conserved in bacteria [Function unknown].	9.50091e-54
NZ_CP047813.1\|WP_000169042.1\|1344237_1344462_+\|DUF2922-domain-containing-protein	gnl\|CDD\|378571	pfam11148, DUF2922, Protein of unknown function (DUF2922). This bacterial family of proteins has no known function.	1.74707e-13
NZ_CP047813.1\|WP_043044698.1\|1344656_1345586_+\|DMT-family-transporter	gnl\|CDD\|225778	COG3238, COG3238, Uncharacterized protein conserved in bacteria [Function unknown].	1.51869e-36
NZ_CP047813.1\|WP_000808896.1\|1362013_1362952_-\|aldo/keto-reductase	gnl\|CDD\|381309	cd19083, AKR_AKR11A1_11D1, AKR11A and AKR11D families of aldo-keto reductase (AKR). Bacillus subtilis aldo-keto reductase IolS, also called vegetative protein 147 (VEG147), is a founding member of aldo-keto reductase family 11 member A1 (AKR11A1). It is able to reduce the standard aldo-keto reductase (AKR) substrates DL-glyceraldehyde, D-erythrose, and methylglyoxal in the presence of NADPH, albeit with poor efficiency in vitro. Bacillus aryabhattai aldo keto reductase is a founding member of aldo-keto reductase family 11 member D1 (AKR11D1).	3.61827e-168
NZ_CP047813.1\|WP_001018677.1\|1346533_1346908_+\|transcriptional-regulator	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	1.77309e-26
NZ_CP047813.1\|WP_000362978.1\|1349633_1350434_-\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	2.45049e-26
NZ_CP047813.1\|WP_000901749.1\|1353617_1354253_-\|endonuclease-III-domain-containing-protein	gnl\|CDD\|225140	COG2231, COG2231, Uncharacterized protein related to Endonuclease III [DNA replication, recombination, and repair].	9.55275e-93
NZ_CP047813.1\|WP_001790232.1\|1351191_1352142_-\|iron-ABC-transporter-permease	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	5.19191e-48
NZ_CP047813.1\|WP_070005418.1\|1347156_1347945_-\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.93023e-34
NZ_CP047813.1\|WP_000923049.1\|1363221_1363848_-\|DUF443-domain-containing-protein	gnl\|CDD\|335700	pfam04276, DUF443, Protein of unknown function (DUF443). Family of uncharacterized proteins.	2.34802e-60
NZ_CP047813.1\|WP_000180230.1\|1358996_1360292_-\|HD-domain-containing-protein	gnl\|CDD\|224004	COG1078, COG1078, HD superfamily phosphohydrolases [General function prediction only].	1.70707e-150
NZ_CP047813.1\|WP_001200748.1\|1356938_1357949_-\|alcohol-dehydrogenase-AdhP	gnl\|CDD\|181842	PRK09422, PRK09422, ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional.	0

>NZ_CP047813.1|WP_072399260.1|1352289_1353117_-|ABC-transporter-substrate-binding-protein
MKDNDKQGSDDNGSSKSPYHRIVSLIPSNTEILYELGLGKYIVGVSTVDDYPKDVKKGKKQFDALNLNKEELLKAKPDLILAHESQKATANKVLSSLEKQGIKVVYVKDAQSIDETYNTFKQIGKLTHHDKQAEQLVEETKDNIDKVIDSIPAHHKKSKVFIEVSSKPEIYTAGKHTFFNDMLEKLEAQNVYSDINGWNPVTKESIIKKNPDILISTEAKTRSDYMDIIKKRGGFNKINAVKNTRIEVVNGDEVSRPGPRIDEGLKELRDAIYRK
>NZ_CP047813.1|WP_001790232.1|1351191_1352142_-|iron-ABC-transporter-permease
MTFNKVLLSWIVILIITTSIYLFWQLGDINDVFNQSILINVRLPRLLEALLTGMILTVAGLIFQTVLNNALADSFTLGLASGATFGSGLALFLGLTTLWIPVFSITFSLITLITVLVITSVLSQGYPVRILILSGLMIGALFNSLLYFLILLKPRKLNTIANYLFGGFGDAEYSNVSIIAITFIIALFGIFIILNQLKLLQLGELKSQSLGLNVQLITYIALCIASMITAINVAYVGIIGFIGMVIPQLIRKWQWKQSLGRQLALNIVTGGQIMVMADFIGSHILSPVQIPASIIIALIGIPVLFYMLISQSKRLH
>NZ_CP047813.1|WP_000365354.1|1350417_1351137_-|HAD-family-hydrolase
MDLNQIKAVVFDLEGTLLDRVKSREKFIEEQYERFHDYLIHVQLADFKKAFIELDDDEDNDKPDLYKEIIKRFHVDRLTWKDLFNDFEMHFYRYVFPYYDTLYTLEKLSQKGFQIGVIANGKSKIKQFRLHSLGLMHVINYLSTSETVGFRKPHPKIFEDMIDQLGVLPEQIMYVGDDALNDVAPARAMGMVSVWYKQEDAEIEPLEEEVDFTITTVEELLTILPIKNDNKGENYGSIY
>NZ_CP047813.1|WP_000362978.1|1349633_1350434_-|alpha/beta-hydrolase
MDLFTRKDGTSIHYSTLGEGYPIVLIHTVLDNYSVFNKLAAQLAKSFQVVLIDLRGHGYSDKPRHIEIKDFSDDIVELLKYLYIEEVAFVCHEMGGIIGADISVRYPEFTSSLMLVNPTSIEGELPEERLFRKYAHIIRNWDPEKQDKFLNKRKYYRPRKMNRFLKHVVDTNEISTKEEIQAVKEVFKNADISQTYRNVVVPTKIIAGEFGERTTRLEAKEVADLIQNADFEVYQESSAFPFVEEQERFVEDTASFINKHHDEKHV
>NZ_CP047813.1|WP_000735551.1|1348991_1349498_-|hypothetical-protein
MKKLLTASIIACSVLMGVGIANTNAEAASGNSIDTVKQLIKGDQSLENVKIGESIKDVLTKYKNPMYSYNEDGTEHYYEFHTKKGMLLVTTDGKKNNGKVTHISMMYNDANGPTYQAVKNYVGKAVTHTEYSKVAGNFGYIEKGKTTYQFASAPKDKNIKLYRIDLEK
>NZ_CP047813.1|WP_001222133.1|1348113_1348830_-|hypothetical-protein
MRINDKILLENIEDYFNHKGLSPHLIDDIKEKVITDIKNSEKKDQDYIEYKRKSPAQIILMIQRNLFALQMNPVIFFIINFILISYLYDKQYVQFQAITGMSLFYCLVIFPMTIVVYLRVSQKNYLRSNKIEMIMGTIIAIISLLLIILQAFNITWGVIPITNFGHQFFFFIGIILVIAGIFYKRLEFSGIGLLFCQKTVDAMIHNPQSAQIFSLIIWILLVVLVIYFTIRLSSRTRL
>NZ_CP047813.1|WP_070005418.1|1347156_1347945_-|alpha/beta-hydrolase
MNKVTINPQIQLTYQIEGKGDPIILLHGLDGNLAGFEDLQHQLASSYKVLSYDLRGHGKSSKSESYDLNDHVEDLKILMEKLNIHEAHILGHDLGGVVAKLFTDKYAYRVKSLTTIASKKDDLIHSFTQLLIQYQDDIAGFNKSEAYILLFSKLFRNQEKTMKWYQKQRIYSIKSEDDSAVAIRSLILHKDEPMYLKKRTCVPTLLINGEHDPLIKDKNHFKLEAHFLNVTKKIFEHSGHAPHIEEPEAFMNYYLNFLKSVS
>NZ_CP047813.1|WP_001018677.1|1346533_1346908_+|transcriptional-regulator
MAITKINDCFELLSMVTYADKLKSLIKKEFSISFEEFAVLTYISENKEKEYYLKDIINHLNYKQPQVVKAVKILSQEDYFDKKRNEHDERTVLILVNAQQRKKIESLLSRVNKRITEANNEIEL
>NZ_CP047813.1|WP_043044698.1|1344656_1345586_+|DMT-family-transporter
MLLFYIIGVLVGMLIPIQTSVNSRLSLYTKSPFYTSFISFSVGTICLIILNIIINPEVFTIHFYNNQSFNYTWVVGGLLGVSFLTGNLLLLPKLGATLTVITTVAGQIIMGVIIDTFGLFGATIHDFNLIKAIGVLLLIVGIVIMNQFNKNNLLLTDQKYLLFWLLLGFIFGFFPPIQTTINSALASHTHSPAFASLVSFTIGSIALLILTAIFNRSLKLKTSHLKFGKLKPIYFTGGILGMAFVTANIILMPHMGAALTTLIGMFGQILMGILIDHFGLFGPPKIAMTSRKTIGLLCILTGIILLRLF
>NZ_CP047813.1|WP_000169042.1|1344237_1344462_+|DUF2922-domain-containing-protein
MTKTLELSFKSSLDKPVKLQLPQLNNVVTEQVARDSMNALVDLNIIKSNSGTITKVHSAQIIDKTTTVLFEDKK
>NZ_CP047813.1|WP_000901749.1|1353617_1354253_-|endonuclease-III-domain-containing-protein
MLGTDELYKLLYRHMGPQNWWPADNDIELMLGAILVQNTRWRNAEIALNQIKEHTHFNPNHILELPIETLQSLIHSSGFYKSKSLTIKTLLTWLARHHFNYQEINERYKGGLRKELLSLKGIGSETADVLLVYIFGRIEFIPDSYTRKIYDKLGYENTKNYDQLKKVVTLPNHFTNQDANEFHALLDVFGKHYFRDKDIKNYDFLEPYFKK
>NZ_CP047813.1|WP_043044703.1|1354588_1356250_-|arginine--tRNA-ligase
MNIIDQVKQTLVEEIAASINKAGLADEIPDIKIEVPKDTKNGDYATNIAMVLTKIAKRNPREIAQAIVDNLDTEKAHVKQIDIAGPGFINFYLDNQYLTAIIPEAIEKGDQFGHVNESKGQNVLLEYVSANPTGDLHIGHARNAAVGDALANILTAAGYNVTREYYINDAGNQITNLARSIETRFFEALGDNSYSMPEDGYNGKDIIEIGKDLAEKHPEIKDYSEEARLKEFRKLGVEYEMAKLKNDLAEFNTHFDNWFSETSLYEKGEILEVLAKMKELGYTYEADGATWLRTTDFKDDKDRVLIKNDGTYTYFLPDIAYHFDKVKRANDILIDLFGADHHGYINRLKASLETFGVDSNRLEIQIMQMVRLMENGKEVKMSKRTGNAITLREIMDEVGVDAARYFLTMRSPDSHFDFDMELAKEQSQDNPVYYAQYAHARICSILKQAKEQGIEVAAANDFTTITNEKAIELLKKVADFEPTIESAAEHRSAHRITNYIQDLASHFHKFYNAEKVLTDDIEKTKAHVAMIEAVRITLKNALAMVGVSAPESM
>NZ_CP047813.1|WP_001819741.1|1356246_1356630_-|DUF1934-family-protein
MLKQHNEKEKFEFTTEGTWQQRQSNFIRYVEQIEDATVNVTIKVDDDSVKLIRKGDINMNLHFVEGQTTTTFYDISAGRIPLEVKTLRILHFVSGDGGKLKIHYELYQDNEKMGSYQYEINYKEIGE
>NZ_CP047813.1|WP_001200748.1|1356938_1357949_-|alcohol-dehydrogenase-AdhP
MRAAVVTKDHKVSIEDKKLRALKPGEALVQTEYCGVCHTDLHVKNADFGDVTGVTLGHEGIGKVIEVAEDVESLKIGDRVSIAWMFESCGRCEYCTTGRETLCRSVKNAGYTVDGAMAEQVIVTADYAVKVPEKLDPAAASSITCAGVTTYKAVKVSNVKPGQWLGVFGIGGLGNLALQYAKNVMGAKIVAFDINDDKLAFAKELGADAIINSKDVDPVAEVMKLTDNKGLDATVVTSVAKTPFNQAVDVVKAGARVVAVGLPVDKMNLDIPRLVLDGIEVVGSLVGTRQDLREAFEFAAENKVTPKVQLRKLEEINDIFEEMENGTITGRMVIKF
>NZ_CP047813.1|WP_001788287.1|1358447_1358969_-|hypothetical-protein
MEVISLSEKKGFNFNIIKNDPLDGHKGTNIGSISLDNIAPVFIDVANKEAFIDIGGMHARAKVEKGVKWITDKAAVEGDEAKEYWLCWVTTERNEQGPYYAGLTACYLLVNKAIRRGYKSMPEHVNMMDKSMKHHIIIDQIGDENKAILKDFLMNHDEGMWKHSSDALHQAFN
>NZ_CP047813.1|WP_000180230.1|1358996_1360292_-|HD-domain-containing-protein
MTNAYVDLKLVEEKVFKDPIHRYIHVEDQLIWDLIKTKEFQRLRRIRQLGTLYLSFHTAEHSRFGHSLGVYEIVRRLIDESFIGHDAWDNKDRPLALCAALLHDLGHGPFSHSFEKIFNTDHEAYTQAIITGDTEVNAVLRKVAPEFPREVAEVINKTHHNKLVISMISSQIDADRMDYLQRDAYFTGVSYGAFDMERILRLMRPSKDEVLIKESGMHAVENFIMSRYQMYWQIYFHPVSRGGEVLLNNCLKRAKQLYNEGYEFKLHPHDFIPFFEETVTIEQYVELDEAVVTYYLEKWTKEDDAILSDLASRFINRDLFKYIPFDGSIITISELQELFEAGGINPDYYFVSEAFSDLPYDYDRPGSNRKPIHLLRQDGTIREISNQSLVIHSITGINRQDYKLYYPREMVAKIKDKTIREAIENLINELN
>NZ_CP047813.1|WP_000477504.1|1360331_1360808_-|GNAT-family-N-acetyltransferase
MFKVRQATEKDVVQIRDVATKAWFNTYLNIYAATTVNHLLEASYNEHHLKKRLQEQLFLVVEEGNDIVGFANFIYGEELYLSAHYVKPESQHTGYGTALLNEGLSRFEDKFEGVYLEVDNKNEEAVAYYKEQGFTILRSYEPEMYGEKLDLALMYKAF
>NZ_CP047813.1|WP_000633782.1|1360976_1361513_-|flavodoxin-family-protein
MITVLFGGSRPNGNTAQLTKFALQDLEYQWIDVTQHQFKPIRDVRHTAETITSYDDDYLPILDKILASDTIIFASPVYWYSISAPLKAFIEHWSETLQDKRYPNFKAQMAEKDFRVILVGGDCPKIKAKPAITQMKYSLDFLGATLNGYIIGTAEKPGDIMKDNYALARATEWNSILQ
>NZ_CP047813.1|WP_000808896.1|1362013_1362952_-|aldo/keto-reductase
MKQFVNLGKSDVEVFPIALGTNAVGGHNLYPNLDEEQGKDVVRQAINHGINLLDTAYIYGPERSEELVGEVVKEYPREQIKIATKGSHEFDENQEVHQNNQPEYLKQQVENSLKRLQTDYIDLYYIHFPDDNTPKDQAVAALQELKEQGKIKAIGVSNFTLDQLKEANKDGYVDVVQLEYNLLHRENEAVLQYCVDHQITFIPYFPLASGILAGKYDENTKFSDHRTTRRDFKPGVFEENVRRVKALESIAAAHQTSIANIVLAFYLTRPAIDVIIPGAKRAEQVVENIKAADIVLSDDEIQYIDELFPIED
>NZ_CP047813.1|WP_000923049.1|1363221_1363848_-|DUF443-domain-containing-protein
MLLCESKIINKNPKYRIIKYNDEYLMVDIISTWISLFFPFINWFIPKRYVKISREEFENLNIVKPAKKNVFWPVAGSSALLGVALRKYTHLLDIQLDKKLVIAICCITFIGILIFYVRLIKKSSLNIYNTKNKRSKIFLIPTLKNVCFTLFGYILFGGLTMLFLDALLSMSYQNIIVYFVWIAVIMGFFLVNIALIIDKNIHVILKNQ

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Crispr_ID: NZ_CP047813_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047813_9

1722141-1722219

Orphan

Consensus_repeat	Method
TGTTGGGGCCCAGCCAACTTGCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP047813_9

>merge|NZ_CP047813|9|1722141-1722219|CRISPRCasFinder
TGTTGGGGCCCAGCCAACTTGCACATTATTGTAAGCTGACTTTCCGCCAGCTTCTATGTTGGGGCCCCGCCAACTTGCA

>NZ_CP047813|9|8|1722141-1722219|CRISPRCasFinder
TGTTGGGGCCCAGCCAACTTGCA	CATTATTGTAAGCTGACTTTCCGCCAGCTTCTA
TGTTGGGGCCCCGCCAACTTGCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047813.1\|WP_160186729.1\|1732105_1733794_-\|CDP-glycerol-glycerophosphotransferase-family-protein	unknown	unknown	gnl\|CDD\|367953
NZ_CP047813.1\|WP_000182742.1\|1719918_1720833_+\|ribokinase	unknown	unknown	gnl\|CDD\|274000
NZ_CP047813.1\|WP_006191669.1\|1713857_1714850_-\|linear-amide-C-N-hydrolase	unknown	unknown	gnl\|CDD\|225591
NZ_CP047813.1\|WP_001789470.1\|1720930_1721065_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047813.1\|WP_001159764.1\|1716587_1716980_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047813.1\|WP_001792906.1\|1726236_1726680_-\|antiholin-like-murein-hydrolase-modulator-LrgA	unknown	unknown	gnl\|CDD\|235222
NZ_CP047813.1\|WP_043044807.1\|1723790_1724582_-\|PTS-glucose-transporter-subunit-IIABC	unknown	unknown	gnl\|CDD\|225101
NZ_CP047813.1\|WP_000925394.1\|1727535_1729275_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225814
NZ_CP047813.1\|WP_000975365.1\|1730351_1732073_-\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|376098
NZ_CP047813.1\|WP_043044805.1\|1712581_1713532_-\|glycine-glycine-endopeptidase-LytM	unknown	unknown	gnl\|CDD\|366703
NZ_CP047813.1\|WP_043044806.1\|1715083_1716460_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_CP047813.1\|WP_000922326.1\|1724730_1725435_+\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225099
NZ_CP047813.1\|WP_000747873.1\|1719486_1719891_+\|D-ribose-pyranase	unknown	unknown	gnl\|CDD\|183318
NZ_CP047813.1\|WP_000608831.1\|1729533_1730208_-\|iron-sulfur-cluster-repair-di-iron-protein-ScdA	unknown	unknown	gnl\|CDD\|183940
NZ_CP047813.1\|WP_000757884.1\|1717360_1718359_+\|LacI-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525
NZ_CP047813.1\|WP_000163990.1\|1722338_1723775_-\|6-phospho-beta-glucosidase	unknown	unknown	gnl\|CDD\|181973
NZ_CP047813.1\|WP_000031269.1\|1721083_1721845_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NZ_CP047813.1\|WP_000029204.1\|1718590_1719472_+\|ribose-transporter-RbsU	unknown	unknown	gnl\|CDD\|284268
NZ_CP047813.1\|WP_000607067.1\|1725542_1726244_-\|antiholin-like-protein-LrgB	unknown	unknown	gnl\|CDD\|179810
NZ_CP047813.1\|WP_000645456.1\|1726792_1727533_-\|DNA-binding-response-regulator	unknown	unknown	gnl\|CDD\|184495

Protein	Function_ID	Function_description	E-value
NZ_CP047813.1\|WP_160186729.1\|1732105_1733794_-\|CDP-glycerol-glycerophosphotransferase-family-protein	gnl\|CDD\|367953	pfam04464, Glyphos_transf, CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase. Wall-associated teichoic acids are a heterogeneous class of phosphate-rich polymers that are covalently linked to the cell wall peptidoglycan of gram-positive bacteria. They consist of a main chain of phosphodiester-linked polyols and/or sugar moieties attached to peptidoglycan via a linkage unit. CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase is responsible for the polymerization of the main chain of the teichoic acid by sequential transfer of glycerol-phosphate units from CDP-glycerol to the linkage unit lipid.	4.22146e-118
NZ_CP047813.1\|WP_000182742.1\|1719918_1720833_+\|ribokinase	gnl\|CDD\|274000	TIGR02152, Putative_ribokinase, ribokinase. This model describes ribokinase, an enzyme catalyzing the first step in ribose catabolism. The rbsK gene encoding ribokinase typically is found with ribose transport genes. Ribokinase belongs to the carbohydrate kinase pfkB family (pfam00294). In the wide gulf between the current trusted (360 bit) and noise (100 bit) cutoffs are a number of sequences, few of which are clustered with predicted ribose transport genes but many of which are currently annotated as if having ribokinase activity. Most likely some have this function and others do not. [Energy metabolism, Sugars].	1.33376e-142
NZ_CP047813.1\|WP_043044805.1\|1712581_1713532_-\|glycine-glycine-endopeptidase-LytM	gnl\|CDD\|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	6.5002e-32
NZ_CP047813.1\|WP_006191669.1\|1713857_1714850_-\|linear-amide-C-N-hydrolase	gnl\|CDD\|225591	COG3049, COG3049, Penicillin V acylase and related amidases [Cell envelope biogenesis, outer membrane].	1.73012e-151
NZ_CP047813.1\|WP_000975365.1\|1730351_1732073_-\|glycosyltransferase-family-2-protein	gnl\|CDD\|376098	pfam18674, TarS_C1, TarS beta-glycosyltransferase C-terminal domain 1. Beta-glycosyltransferase TarS is an enzyme responsible for the glycosylation of wall teichoic acid polymers of the S. aureus cell wall, a process that has been shown to be specifically responsible for methicillin resistance in MRSA. It contains a trimerization domain composed of tandem carbohydrate binding motifs.The two C-terminally localized regions composed of a series of beta-sheets participate in an extensive trimerization interface and they assume an immunoglobulin-like fold. It is suggested that both carbohydrate binding domains may be involved in polyRboP binding, however unlike pullulanase, the CBMs of TarS are involved in the formation of an extensive trimerization interface.	6.64158e-35
NZ_CP047813.1\|WP_001792906.1\|1726236_1726680_-\|antiholin-like-murein-hydrolase-modulator-LrgA	gnl\|CDD\|235222	PRK04125, PRK04125, antiholin-like protein LrgA.	8.44339e-64
NZ_CP047813.1\|WP_043044807.1\|1723790_1724582_-\|PTS-glucose-transporter-subunit-IIABC	gnl\|CDD\|225101	COG2190, NagE, Phosphotransferase system IIA components [Carbohydrate transport and metabolism].	1.6082e-54
NZ_CP047813.1\|WP_000925394.1\|1727535_1729275_-\|sensor-histidine-kinase	gnl\|CDD\|225814	COG3275, LytS, Putative regulator of cell autolysis [Signal transduction mechanisms].	0
NZ_CP047813.1\|WP_000922326.1\|1724730_1725435_+\|GntR-family-transcriptional-regulator	gnl\|CDD\|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.12182e-62
NZ_CP047813.1\|WP_000757884.1\|1717360_1718359_+\|LacI-family-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	2.77715e-100
NZ_CP047813.1\|WP_000645456.1\|1726792_1727533_-\|DNA-binding-response-regulator	gnl\|CDD\|184495	PRK14084, PRK14084, DNA-binding response regulator.	4.37999e-152
NZ_CP047813.1\|WP_000747873.1\|1719486_1719891_+\|D-ribose-pyranase	gnl\|CDD\|183318	PRK11797, PRK11797, D-ribose pyranase; Provisional.	1.143e-69
NZ_CP047813.1\|WP_043044806.1\|1715083_1716460_+\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.2215e-31
NZ_CP047813.1\|WP_000163990.1\|1722338_1723775_-\|6-phospho-beta-glucosidase	gnl\|CDD\|181973	PRK09589, celA, 6-phospho-beta-glucosidase; Reviewed.	0
NZ_CP047813.1\|WP_000031269.1\|1721083_1721845_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.0131e-27
NZ_CP047813.1\|WP_000029204.1\|1718590_1719472_+\|ribose-transporter-RbsU	gnl\|CDD\|284268	pfam06800, Sugar_transport, Sugar transport protein. This is a family of bacterial sugar transporters approximately 300 residues long. Members include glucose uptake proteins, ribose transport proteins, and several putative and hypothetical membrane proteins probably involved in sugar transport across bacterial membranes. These members are transmembrane proteins which are usually 5+5 duplications. This model recognizes a set of five TMs,.	4.46997e-117
NZ_CP047813.1\|WP_000607067.1\|1725542_1726244_-\|antiholin-like-protein-LrgB	gnl\|CDD\|179810	PRK04288, PRK04288, antiholin-like protein LrgB; Provisional.	5.86643e-124
NZ_CP047813.1\|WP_000608831.1\|1729533_1730208_-\|iron-sulfur-cluster-repair-di-iron-protein-ScdA	gnl\|CDD\|183940	PRK13276, PRK13276, iron-sulfur cluster repair di-iron protein ScdA.	7.18502e-154

>NZ_CP047813.1|WP_000031269.1|1721083_1721845_+|class-I-SAM-dependent-methyltransferase
MSKEAGHTFLAKLGKTRLRPGGKEATDWLIQQGAFSQDKQVLEVACNMCTTSIYLAHTYGCHIQGVDINKKALEKAQENISAAGLESYIQVQQANAVKLPFDDNQFDIVLNEAMLTMLPIAIKEKALREYYRVLKPGGILLTHDIVIVNESHATHVVKSLSAAINVNVSPQTKLGWLDLYNQAGFNHVHYHTGPMSLMTPKGLIYDEGIVGTIKIINNALKKENRSMFCKMFKTMTKLRKDMNYITFVAKKED
>NZ_CP047813.1|WP_001789470.1|1720930_1721065_-|hypothetical-protein
MIIIIINIAYLYAIIWKLKRLQKIVTSFITKHESSSIGLVENYF
>NZ_CP047813.1|WP_000182742.1|1719918_1720833_+|ribokinase
MTNKVVILGSTNVDQFLTVERYAQPGETLHVEEAQKAFGGGKGANQAIATARMQADTTFITKIGTDGVADFILEDFKAAHIDTSYIIKTAEAKTGQAFITVNAEGQNTIYVYGGANMTMTPEDVINAKDAIINADFVVAQLEVPIPAIISAFEIAKAHGVTTVLNPAPAKALPNELLSLIDIIVPNETEAELLSGIKVTNEQSMKDNANYFLSLGIKTVLITLGKQGTYFATKNQSQHIEAYKVNAIDTTAAGDTFIGAFVSRLNKSQDNLADAIDFGNKASSLTVQKHGAQASIPLLEEVNQV
>NZ_CP047813.1|WP_000747873.1|1719486_1719891_+|D-ribose-pyranase
MKKSAVLNEHISKAIATIGHFDLLTINDAGMPIPNDHRRIDLAVTKNLPRFIDVLATVLEEMEIQKIYLAEEIKEHNPTQLQQIKQLISSEIEIIFIPHEEMKSNLAHPLNKGNIRTGETTPYSNIALESNVTF
>NZ_CP047813.1|WP_000029204.1|1718590_1719472_+|ribose-transporter-RbsU
MSIVALLIGLGPLIGWGFFPTVASKFGGKPVHQIIGATVGTLIFAIILAVVTSSGFPTGTNLLFALLSGAGWGFGQIITFKAFELVGSSRAMPVTTAFQLLGASLWGVFALGNWPGIGHKIIGFTALVVILIGARMTVWSERKEASNAKNLRRAVVLLLIGEFGYWLYSAAPQATSIDGLTAFLPQAMGMVIVAVIYGFMNMKAENPFRNKITWLQIISGFFFAFGALTYLISAQPNMNGLATGFILSQTSVVLATLTGIYFLKQHKTSKEMVITIIGLVLILVAASVTVFIK
>NZ_CP047813.1|WP_000757884.1|1717360_1718359_+|LacI-family-transcriptional-regulator
MKKVSIKDVAREAGVSVTTVSHILNHNDSRFSATTIKNVHAVSERLGYAPNKHAKQLRGSKIQTIGVILPSLTNPFFSALMQSIHDHKPSDVDLCFLTSTATDLYDNIKHLIDRGIDGLIIAQYISSPDALNNYLKKHHVPYVVLDQNDHQGYTDFVRTNEYQGGQLAAQHLIELGHNNMMIVAPYDMMANMSTRVAGFVDTLRANQLPEPQIVHTELSKRGGLTIVDDIMVQSATAIFAINDELAIGILRGLIEHGISIPKDISLIGYDDIDYAAYVSPPLTTVAQPITDIGKTSLTLLLQRLQHLDKSIDMIELPTTLKIRATTGYHLSN
>NZ_CP047813.1|WP_001159764.1|1716587_1716980_-|hypothetical-protein
MQFKLKEEEIISFLELKYPEKEFEYGRLLVGQHKRDDLDVYYFGDTFLMCTIISFKTFEIKETVELSYDAVNRIVLKDGWLFRKMRIETMQKVLKYGTSKLMLTDFQKDNYNKYIQGQKQRVIFENGHFV
>NZ_CP047813.1|WP_043044806.1|1715083_1716460_+|MFS-transporter
MNNTQSSPRSNIIIAIMLSALTYWLFAQSFINIGPLVGQTYQTSPAVLNLSISLTSFATGIFMVAAGDIADKIGQLRMTYMGLIISMFASLLLIISDITALLIIGRILQGLSAAILLPSTVGVLNNQFKGEHLRRAISYLMISTVGGIGLAGVIGGLIASNFGWQTNFIISIVIAFIAILLLKGTPEKVSQHSHRHPFDYKGMSIFAVMIGSFTLLLTQGFEQGWFSTFSIICLSIFSITTLIFIIIERRHEVPFIDFSVLRNRPFIGAFLNNFVLNSGLGVTVVFFIYAQTHLGLSAAQSGLVTLPYAIVAVAMIRLGEKATLRFGGKLMLIIGPLFPVIGITIISMTSLQPSQYIIAVIIGFVICAIGNGLVATPGLTIAIFSMPNEKVGLATGLYKMSGTLGGAFGIALSTTVFSMLQLNYTPSVAATVTFIVSIVLMILGSLSAYMIIPKTVKS
>NZ_CP047813.1|WP_006191669.1|1713857_1714850_-|linear-amide-C-N-hydrolase
MCTGFTIQTLNNQVLLGRTMDYDYPLDGSPAVTPRNYRWTSRTGTTGQTQYGFIGTGTDMEGFIYGDGVNEHGVAISTQYFRGYSSYGSTHKADAMNITQNEIVTWILGYTTSIEDMKQQASQIHVVAVYLNDIGEVPPLHYHVSDATGHSVEVSFKEGEVVIKDNPIGVLTNHPDLDWHYSNLRQYINISPYPATANLLEGVTIEPLGNEAGTFGLPGGFTSTERFVRMAFMKANIAQNNDKEMDLMNAFYLLDAVNIPIGIVRPHDADNHYTMYQTVINLTTRTLYIKYYGSNELVALKLTDDLINRKDMTIFKPEKHITIRKLNDNQ
>NZ_CP047813.1|WP_043044805.1|1712581_1713532_-|glycine-glycine-endopeptidase-LytM
MKKLTAAAIATMGFATFTMAHQADAAETTNTQQAHTQMSTQSQDVSYGTYYTIDSNGDYHHTPDGNWNQAMFDNKEYSYTFVDAQGHTHYFYNCYPKNANANGSGQTYVNPATAGDNNDYTASQSQQHINQYGYQSNVGPDASYYSHSNNNQAYNSHDGNGKVNSPNGTSNQNGGSASKATASGHATDASWLTSRKQLQPYGQYHGGGAHYGVDYAMPENSPVYSLTDGTVVQAGWSNYGGGNQVTIKEANSNNYQWYMHNNRLTVSAGDKVKAGDQIAYSGSTGNSTAPHVHFQRMSGGIGNQYAVDPTSYLQSR
>NZ_CP047813.1|WP_000163990.1|1722338_1723775_-|6-phospho-beta-glucosidase
MTKLPQNFMWGGALAANQFEGGYDKGGKGLSVIDVMTSGAHGKARQITESIDPNHYYPNHEGIDFYHRYKEDIALFKEMGLKCLRTSIAWTRIFPNGDEDVPNEEGLAFYDRIFDELIAQGIEPVVTLSHFEMPLHLAKHYGGFRNREVVDYFVHFARVVFERYKDKVTYWMTFNEINNQMDTSNPIFLWTNSGVALTENDNPEEVLYQVAHHELLASALAVRLGKEINPKFKIGTMISHVPIYPYSCHPKDMMEAQIANRLRFFFPDVQVRGYYPSYAKKMLARKGYDVGWQEGDDSILQQGTVDYIGFSYYMSTAVKHDVDTTVKNNIVNGGLNHSVENPHIATSDWGWAIDPDGLRYTLNVLYDRYQLPLFIVENGFGAVDEVVDGHIHDDYRIEYLKAHITAAIEAVDQDGVDLIGYTPWGIIDIVSFTTGEMKKRYGLIYVDRDNDGHGTMERLKKDSFYWYQQVIASNGDKL
>NZ_CP047813.1|WP_043044807.1|1723790_1724582_-|PTS-glucose-transporter-subunit-IIABC
MSNKYKEQAQDILTAVGGVENIVDATYDTKCITIHMQHTIPSTANEVKQIVDVTSVAENDAQLVIKLNGNVDEVYQQLQRLIKNANVEEDANTDNINSQDTSYTPQVKVTTPILVKAPIAGRRILLKEVRDSIFREKMVGEGLAIKAHEESKVIAPFNGLISMIVPTKHAVGIQSEDGVDIVIHIGVNTVDLEGKGFKCFVKQNDRVEAGQTLLQFDQQYIQQQGYNADVIVVISNSADLGKVELTMNEIITTEDVIFKIFKN
>NZ_CP047813.1|WP_000922326.1|1724730_1725435_+|GntR-family-transcriptional-regulator
MLKYEHIAKQLNAFIHQSNFKPGDKLPSVTQLKERYQVSKSTIIKALGLLEQDGLIYQAQGSGIYVRNIADANRINVFKTNGFSKSLGEHRMTSKVLVFKEIATPPKSVQDELQLNADDTVYYLERLRFVDDDVLCIEYSYYHKEIVKYLNDDIAKGSIFDYLESNMKLRIGFSDIFFNVDKLTSSEASLLQLSTGEPCLRYHQTFYTMTGKPFDSSDIVFHYRHAQFYIPSKK
>NZ_CP047813.1|WP_000607067.1|1725542_1726244_-|antiholin-like-protein-LrgB
MINHLALNTPYFGILLSVIPFFLATILFEKTNRFFLFAPLFVSMVFGVAFLYLTGIPYKTYKIGGDIIYFFLEPATICFAIPLYKKREVLVKHWHRIIGGIGIGTVVALLIILTFAKLAQFANDVILSMLPQAATTAIALPVSAGIGGIKELTSLAVILNGVIIYALGNKFLKLFRITNPIARGLALGTSGHTLGVAPAKELGPVEESMASIALVLVGVVVVAVVPVFVAIFF
>NZ_CP047813.1|WP_001792906.1|1726236_1726680_-|antiholin-like-murein-hydrolase-modulator-LrgA
MVVKQQKDASKPAHFFHQVIVIALVLFVSKIIESFMPIPMPASVIGLVLLFVLLCTGAVKLGEVEKVGTTLTNNIGLLFVPAGISVVNSLGVISQAPFLIIGLIIVSTILLLICTGYVTQIIMKVTSRSKGDKVTKKIKIEEAQAHD
>NZ_CP047813.1|WP_000645456.1|1726792_1727533_-|DNA-binding-response-regulator
MKALIIDDEPLARNELTYLLNEIGGFEEINEAENVKETLEALLINQYDIIFLDVNLMDENGIELGAKIQKMKEPPAIIFATAHDQYAVQAFELNATDYILKPFGQKRIEQAVNKVRATKAKDDNSASAIANDMSANFDQSLPVEIDDKIHMLKQQNIIGIGTHNGITTIHTTNHKYETTEPLNRYEKRLNPAYFIRIHRSYIINTKHIKEVQQWFNYTYMVILTNGVKMQVGRSFMKDFKASIGLL
>NZ_CP047813.1|WP_000925394.1|1727535_1729275_-|sensor-histidine-kinase
MLLLERVGLIIILAYVLMNIPYFKNLMNRRRTWKARWQLCIIFSLFALMSNLTGIVIDHQHSLSGSVYFRLDDDVSLANTRVLTIGVAGLVGGPFVGLFVGVISGIFRVYMGGADAQVYLISSIFIGIIAGYFGLQAQRRKRYPSIAKSAMIGIVMEMIQMLSILTFSHDKAYAVDLISLIALPMIIVNSVGTAIFMSIIISTLKQEEQMKAVQTHDVLQLMNQTLPYFKEGLNRESAQQIAMIIKNLMKVSAVAITSKNEILSHVGAGSDHHIPTNEILTSLSKDVLKSGKLKEVHTKEEIGCSHPNCPLRAAIVIPLEMHGSIVGTLKMYFTNPNDLTFVERQLAEGLANIFSSQIELGEAETQSKLLKDAEIKSLQAQVSPHFFFNSINTISALVRINSEKARELLLELSYFFRANLQGSKQHTITLDKELSQVRAYLSLEQARYPGRFNININVEDKYRDVLVPPFLIQILVENAIKHAFTNRKQGNDIDVSVIKETATHVRIIVQDNGQGISKDKMHLLGETSVESESGTGSALENLNLRLKGLFGKSAALQFESTSSGTTFWCVLPYERQEEE
>NZ_CP047813.1|WP_000608831.1|1729533_1730208_-|iron-sulfur-cluster-repair-di-iron-protein-ScdA
MINKNDIVADVVTDYPKAADIFRSVGIDFCCGGQVSIEAASLEKKNVDLNELLQRLNDVEQTNTPGSLNPKFLNVSSLIQYIQAAYHEPLREEFKNLTPYVTKLSKVHGPNHPYLVELKETYDTFKNGMLEHMQKEDDVDFPKLIKYEQGEVVDDINTVIDDLVSDHIATGQLLVKMSDLTSSYEPPIEACGTWRLVYQRLKALEVLTHEHVHLENHVLFKKVS
>NZ_CP047813.1|WP_000975365.1|1730351_1732073_-|glycosyltransferase-family-2-protein
MMKFSVIVPTYNSEKYITELLNSLAKQDFPKTEFEVVVVDDCSTDQTLQIVEKYRNKLNLKVSQLETNSGGPGKPRNVALKQAEGEFVLFVDSDDYINKETLKDAAAFIDEHHSDVLLIKMKGVNGRGVPQSMFKETAPEVTLLNSRIIYTLSPTKIYRTTLLKDNDIYFPEELKSAEDQLFTMKAYLNANRISVLSDKAYYYATKREGEHMSSAYVSPEDFYEVMRLIAVEILNADLEEAHKDQILAEFLNRHFSFSRTNGFSLKVKLEDQPQWINALGDFIQAVPERVDALVMSKLRPLLHYARAKDIDNYRTVEESYRQGQYYRFDIVDGKLNIQFNEGEPYFEGIDIAKPKVKMTAFKFDNHKIVTELTLNEFMIGEGHYDVRLKLHSRNKKHTMYVPLSVNANKQYRFNIMLEDIKAYLPKEKIWDVFLEVQIGTEVFEVRVGNQRNKYAYTAETSALIHLNNDFYRLTPYFTKDFNNISLYFTAITLTDSISLKLKGKNKIILTGLDRGYVFEEGMASVVLKDDMIMGMLSQTSENEVEILLSKDIKKRDFKNIVKLNTAHMTYSLK
>NZ_CP047813.1|WP_160186729.1|1732105_1733794_-|CDP-glycerol-glycerophosphotransferase-family-protein
MVKSKIYIDKIYWERVQLFVEGHSENLDLEDSNFVLRNLTETRTMKANDVKIDGNQFVCRFNVAILDNGYYLPEDKYLLVNEQELDYIAQLNPDVINDAYQNLKPEQEEEYNELETQNGKINFLLQTYLKEFRKGGISKKTVYTVTPEISSDVNEFVLDVVVTTPEVKSIYIVRKYKELRKYFRKQSFNTRQFIFKAIFNTTKFFHLKKGNTVLFTSDSRPTMSGNFEYIYNEMLRQNLDKKYDIHTVFKANITDRRGIIDKFRLPYLLGKADYIFVDDFHPLIYTVRFRRSQEVIQVWHAVGAFKIVGFSRTGKKGGPFIDSLNHRSYTKAYVSSETDIPFYAEAFGIKEKNVVPTGVPRTDVLFDEAYATQIKQEMEDELPIIKGKKVILFAPTFRGSGHGTAHYPFFKIDFERLARYCEKNNAVVLFKMHPFVKNRLNIADKHKQYFVDVSDFREVNDILFITDLLISDYSSLIYEYAVFKKPMIFYAFDLEDYITTRDFYEPYESFVPGKIVQSFDALMDALDNEDYEGEKVIPFLDKHFKYQDGRSSERLVRNLFGS

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Crispr_ID: NZ_CP047813_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047813_10

2137965-2138046

Orphan

Consensus_repeat	Method
CCCCAACTTGCATTGTCTGTAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP047813_10

>merge|NZ_CP047813|10|2137965-2138046|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAAATTGGGAATCCAATTTCTCTTTGTTGGGGCCCATCCCCAACTTGCATTGCCTGTAGAA

>NZ_CP047813|10|9|2137965-2138046|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAA	ATTGGGAATCCAATTTCTCTTTGTTGGGGCCCAT
CCCCAACTTGCATTGCCTGTAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047813.1\|WP_000616227.1\|2137481_2137859_+\|glyoxalase	unknown	unknown	gnl\|CDD\|226134
NZ_CP047813.1\|WP_001224187.1\|2135636_2136194_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP047813.1\|WP_001795157.1\|2138713_2139214_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047813.1\|WP_072353801.1\|2139411_2139981_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP047813.1\|WP_000200684.1\|2140390_2141446_+\|PTS-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226167
NZ_CP047813.1\|WP_000751267.1\|2142053_2142755_+\|lytic-transglycosylase-IsaA	unknown	unknown	gnl\|CDD\|381607
NZ_CP047813.1\|WP_000160458.1\|2147036_2148530_+\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224154
NZ_CP047813.1\|WP_001795496.1\|2146555_2147044_+\|glycosyl-4,4'-diaponeurosporenoate-acyltransferase	unknown	unknown	unknown
NZ_CP047813.1\|WP_000651837.1\|2136643_2137465_+\|NmrA/HSCARG-family-protein	unknown	unknown	gnl\|CDD\|187561
NZ_CP047813.1\|WP_000836425.1\|2133831_2134842_-\|amidohydrolase	unknown	unknown	gnl\|CDD\|225070
NZ_CP047813.1\|WP_000697134.1\|2138263_2138494_-\|DUF896-domain-containing-protein	unknown	unknown	gnl\|CDD\|226677
NZ_CP047813.1\|WP_000895193.1\|2130507_2131848_+\|ferrous-iron-transporter-B	unknown	unknown	gnl\|CDD\|223447
NZ_CP047813.1\|WP_000055856.1\|2136324_2136624_+\|DUF2316-family-protein	unknown	unknown	gnl\|CDD\|226806
NZ_CP047813.1\|WP_000448899.1\|2132981_2133812_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP047813.1\|WP_043044907.1\|2134939_2135644_-\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|187585
NZ_CP047813.1\|WP_043044908.1\|2145613_2146381_+\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_CP047813.1\|WP_001791985.1\|2140135_2140264_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047813.1\|WP_001163740.1\|2129407_2130514_+\|NAD(P)-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|379355
NZ_CP047813.1\|WP_000379825.1\|2143441_2145253_+\|O-acetyltransferase-OatA	unknown	unknown	gnl\|CDD\|224748
NZ_CP047813.1\|WP_000706519.1\|2131944_2132835_+\|GTP-binding-protein	unknown	unknown	gnl\|CDD\|223597

Protein	Function_ID	Function_description	E-value
NZ_CP047813.1\|WP_000616227.1\|2137481_2137859_+\|glyoxalase	gnl\|CDD\|226134	COG3607, COG3607, Predicted lactoylglutathione lyase [General function prediction only].	1.48638e-58
NZ_CP047813.1\|WP_001224187.1\|2135636_2136194_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	2.73922e-13
NZ_CP047813.1\|WP_000751267.1\|2142053_2142755_+\|lytic-transglycosylase-IsaA	gnl\|CDD\|381607	cd13925, RPF, core lysozyme-like domain of resuscitation-promoting factor proteins. Resuscitation-promoting factor (RPF) proteins, found in various (G+C)-rich Gram-positive bacteria, act to reactivate cultures from stationary phase. This protein shares elements of the structural core of lysozyme and related proteins. Furthermore, it shares a conserved active site glutamate which is required for activity, and has a polysaccharide binding cleft that corresponds to the peptidoglycan binding cleft of lysozyme. Muralytic activity of Rpf in Micrococcus luteus correlates with resuscitation, supporting a mechanism dependent on cleavage of peptidoglycan by RPF.	3.60255e-06
NZ_CP047813.1\|WP_072353801.1\|2139411_2139981_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.87835e-07
NZ_CP047813.1\|WP_000200684.1\|2140390_2141446_+\|PTS-transporter-subunit-IIC	gnl\|CDD\|226167	COG3641, PfoR, Predicted membrane protein, putative toxin regulator [General function prediction only].	5.38046e-117
NZ_CP047813.1\|WP_000160458.1\|2147036_2148530_+\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224154	COG1233, COG1233, Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	7.55155e-133
NZ_CP047813.1\|WP_000651837.1\|2136643_2137465_+\|NmrA/HSCARG-family-protein	gnl\|CDD\|187561	cd05251, NmrA_like_SDR_a, NmrA (a transcriptional regulator) and HSCARG (an NADPH sensor) like proteins, atypical (a) SDRs. NmrA and HSCARG like proteins. NmrA is a negative transcriptional regulator of various fungi, involved in the post-translational modulation of the GATA-type transcription factor AreA. NmrA lacks the canonical GXXGXXG NAD-binding motif and has altered residues at the catalytic triad, including a Met instead of the critical Tyr residue. NmrA may bind nucleotides but appears to lack any dehydrogenase activity. HSCARG has been identified as a putative NADP-sensing molecule, and redistributes and restructures in response to NADPH/NADP ratios. Like NmrA, it lacks most of the active site residues of the SDR family, but has an NAD(P)-binding motif similar to the extended SDR family, GXXGXXG. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Atypical SDRs are distinct from classical SDRs. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	6.56436e-84
NZ_CP047813.1\|WP_000836425.1\|2133831_2134842_-\|amidohydrolase	gnl\|CDD\|225070	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only].	7.39377e-78
NZ_CP047813.1\|WP_000697134.1\|2138263_2138494_-\|DUF896-domain-containing-protein	gnl\|CDD\|226677	COG4224, COG4224, Uncharacterized protein conserved in bacteria [Function unknown].	6.01061e-31
NZ_CP047813.1\|WP_000895193.1\|2130507_2131848_+\|ferrous-iron-transporter-B	gnl\|CDD\|223447	COG0370, FeoB, Fe2+ transport system protein B [Inorganic ion transport and metabolism].	1.90855e-93
NZ_CP047813.1\|WP_000055856.1\|2136324_2136624_+\|DUF2316-family-protein	gnl\|CDD\|226806	COG4367, COG4367, Uncharacterized protein conserved in bacteria [Function unknown].	4.16565e-40
NZ_CP047813.1\|WP_000448899.1\|2132981_2133812_-\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.6811e-18
NZ_CP047813.1\|WP_043044907.1\|2134939_2135644_-\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|187585	cd05324, carb_red_PTCR-like_SDR_c, Porcine testicular carbonyl reductase (PTCR)-like, classical (c) SDRs. PTCR is a classical SDR which catalyzes the NADPH-dependent reduction of ketones on steroids and prostaglandins. Unlike most SDRs, PTCR functions as a monomer. This subgroup also includes human carbonyl reductase 1 (CBR1) and CBR3. CBR1 is an NADPH-dependent SDR with broad substrate specificity and may be responsible for the in vivo reduction of quinones, prostaglandins, and other carbonyl-containing compounds. In addition it includes poppy NADPH-dependent salutaridine reductase which catalyzes the stereospecific reduction of salutaridine to 7(S)-salutaridinol in the biosynthesis of morphine, and Arabidopsis SDR1,a menthone reductase, which catalyzes the reduction of menthone to neomenthol, a compound with antimicrobial activity; SDR1 can also carry out neomenthol oxidation. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	1.29007e-66
NZ_CP047813.1\|WP_043044908.1\|2145613_2146381_+\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	3.65358e-31
NZ_CP047813.1\|WP_001163740.1\|2129407_2130514_+\|NAD(P)-binding-domain-containing-protein	gnl\|CDD\|379355	pfam13738, Pyr_redox_3, Pyridine nucleotide-disulphide oxidoreductase.	4.45347e-126
NZ_CP047813.1\|WP_000379825.1\|2143441_2145253_+\|O-acetyltransferase-OatA	gnl\|CDD\|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	4.99476e-84
NZ_CP047813.1\|WP_000706519.1\|2131944_2132835_+\|GTP-binding-protein	gnl\|CDD\|223597	COG0523, COG0523, Putative GTPases (G3E family) [General function prediction only].	2.17569e-76

>NZ_CP047813.1|WP_000616227.1|2137481_2137859_+|glyoxalase
MIQSMWFNLHVQDLEKSAQFYKALGFKINRNPQMLDKMVGIQIGQTTVILIENKHFQNVSQQSLNTEPNEVMISLGVNTNEEVDQLVNKVKEAGGTVVQEPTVSQGFYGAMFKDLDGHHFNFLVC
>NZ_CP047813.1|WP_000651837.1|2136643_2137465_+|NmrA/HSCARG-family-protein
MKDILVIGATGKQGNAVVKQLLEDGWYVSALTRNKNNRKLSDIGHPHLSIVEGDLSDNVSLQSAMKGKYGLYSIQPIVKDDVSEELRQGMKIIEIAEQENIQHIVYSTAGGVNRNRTGPHFEVLAKIENRLMESNINATVIKPSFFMDNFLRIAKVEDERITLPEFINPNIKFTMISSIDIAKIASYIFAHPQSFTHQSIEIGSDEVTLSEAATIFSEVTGKSTVIEGEFVSGVAEKQWLEEKGYEVDFELMAEINPTRLSLSDWLKVQNYNK
>NZ_CP047813.1|WP_000055856.1|2136324_2136624_+|DUF2316-family-protein
MSLNKEQRRITAEELQAHFEESTLSVQMIAEKLNVTTEDVEKVLAMTAPLGIFSHQLQRFIHLVWDVRDVINDNIKGNGQTPEPYTYLKGEKEDYWFLR
>NZ_CP047813.1|WP_001224187.1|2135636_2136194_-|TetR/AcrR-family-transcriptional-regulator
MRKDAKENRQRIEEIAHKLFDEEGVENISMNRIAKELGIGMGTLYRHFKDKSDLCYYVIQRDLDIFITHFKQIKDDYHSNYEVMQVSLDYLLQFKIDNKALLQCIEAGNNKLRFYQSAFYQELFDFYYDLFKSDDDTYTKFKTDMLLQSLSTSVFAFQIEHRHISIEAYRNYLLNIYLDEVERND
>NZ_CP047813.1|WP_043044907.1|2134939_2135644_-|SDR-family-NAD(P)-dependent-oxidoreductase
MTKIVLITGGNKGLGYASAEALKALGYKVYIGSRNDVRGQQASQKLGVHYVQLDVTSDYSVKNAYNMIAEKEGRLDILINNAGISGQFSAPSKLTPRDVEEVYQTNVFGIVRMMNTFVPLLEKSEQPVVVNVSSGLGSFGMVTNPETAESKVNSLAYCSSKSAVTMLTLQYAKGLPNMQINAADPGATNTDLVGDFSNNSKHVSEGIKPIIQLATISADGPTGTFINGDGEMPW
>NZ_CP047813.1|WP_000836425.1|2133831_2134842_-|amidohydrolase
MKSITFEEHYVIEDIQKETMNAISADPKGVPMKVMLEGLEKKTGFTNADELSHHDERIQFMNNQDVQIQVLSYGNGSPSNLVGQKAIELCQKANDQLANYIAQYPNRFVGFATLPINEPEAAAREFERCINDLGFKGALIMGRAQDGFLDQDKYDIIFKTAENLGVPIYLHPAPVNSDIYQSYYKGNYPEVTAATFACFGYGWHIDVGIHAIHLVLSGIFDRYPKLNMIIGHWGEFIPFFLERMDEALFAEHLNHPVSYYFKNNFYITPSGMLTKPQFDLVKKEVGIDRILYAADYPYIEPEKLGVFLDELGLTDEEKEKISYTNGAKLLGLSSNN
>NZ_CP047813.1|WP_000448899.1|2132981_2133812_-|alpha/beta-hydrolase
METLELQGAKLRYHQVGQGPVLIFIPGANGTGDIFLPLAEQLKDHFTVVAVDRRDYGESELTEPIPDSASNPDSDYRVKRDAQDIAELAKSLSDEPVYILGSSSGSIVAMHVLKDYPEVVKKIAFHEPPINTFLPDSTYWKDKNDDIVHQILTEGLEKGMKTFGETLNIAPIDAKMMSQPADTEEGRIEQYKRTMFWSKFEIRQYTHSDITLDDFTKYSDKITLLNGTDSRGSFPQDVNFYINKETGIPIVDIPGGHLGYIQKPEGFADVLLNLWG
>NZ_CP047813.1|WP_000706519.1|2131944_2132835_+|GTP-binding-protein
MKIVIIGGFLGGGKTTVLNHLLAESLKESLKPAVIMNEFGKMSVDGALVSEDIPLSELTEGCICCAMKADVSEQLHQLYLKEQPDIVFIECSGIAEPVSVLDACLTPILAPFTTITHMIGVIDASMYKHIKSFPKDIQGLFYEQLAYCSVLFVNKIDSADVETTSKLLKDLEVINPEADIQVGMHGSVTLPISVRQMTATSDNKHKSLHQMINHQFVQSPVKCTKAEFIKRLACLPSHIYRLKGFMTFEDTAHTYLIQFTQGQYELTPVAFSKKVPEYLVLIGKGISKEDYQCLEQ
>NZ_CP047813.1|WP_000895193.1|2130507_2131848_+|ferrous-iron-transporter-B
MLEVKYDMRTGHYTPIPNEPHYLVISHADKLTATEKAKLRLLIIKQKLDISLAESVVSSPIASEHVIEQLTLFQHERRHLRPKISATFLAWLLIFLMFALPIGIAYQFSDWFQNQYVSAWIEYLTQTTLLNHDILQHILFGDYGVLSLGTYSLVWALPVVILISLSTAIIDQTGLKSWMIWAIEPSMLRIGLQGNDIVPLLEGFGCNAAAISQAAHQCHTCTKTQCMSLISFGSSCSYQIGATLSIFSVAGKSWLFMPYLILVLLGGILHNRIWLKKNDQQLSVPLPYDRQLHMPNIRQMLLQMWQNIQMFIVQALPIFITICLIVSILSLTPILNVLSQIFTPILSLLGISSELSPGILFSMIRKDGMLLFNLHQGALLQGMTATQLLLLVFFSSTFTACSVTMTMLLKHLGGQSALKLIGKQMVTSLSLVIGVGIIVKIVMLII
>NZ_CP047813.1|WP_001163740.1|2129407_2130514_+|NAD(P)-binding-domain-containing-protein
MQHHKVAIIGAGAAGIGMAITLKDFGITDVIILEKGTVGHSFKHWPKSTLTITPSFTSNGFGMPDMNAISMDTSPAFTFNEEHISGETYAEYLQVVANHYELNIFENTVVTNISVDDAFYTIATTTETYHADYIFVATGDYNFPKKPFKYGIHYSEIEDFDNFNKGQYVVIGGNESGFDAAYQLAKNGSDIALYTSTTGLNDPDADPSVRLSPYTRQRLGNVIKQGARIEMNVHYTVKDIDFNNGQYHISFDSGQSVHTPHEPILATGFDATKNPIVQQLFVTTNQDIKLTTHDESTRYPNIFMIGATVENDNAKLCYIYKFRARFAVLAHLLTQREGLPAKQEVIENYQKNQMYLDDYSCCEVSCTC
>NZ_CP047813.1|WP_000697134.1|2138263_2138494_-|DUF896-domain-containing-protein
MKILDRINELANKEKVQPLTVAEKQEQHALRQDYLSMIRGQVLTTFSTIKVVDPIGQDVTPDKVYDLRQQYGYIQN
>NZ_CP047813.1|WP_001795157.1|2138713_2139214_-|hypothetical-protein
MTSIFVFAYLNNTSGNMLFRQQMICACLLANVRHSSIVCLNNICCIVDMRCLNTKIGGIDVSETDEPQGFERTHNILNINQSSLGVVTYITNKLKSTLKQHIIIARGKKRIDYRLSYNFYTTYYDNVEIKKIDCEYTYAMPIAILIRHTMSFDNAHFFAQLRHPVL
>NZ_CP047813.1|WP_072353801.1|2139411_2139981_-|TetR/AcrR-family-transcriptional-regulator
MMESKSIDPRIVRTKQLLVDAFLKISREKKLSQITVKDITDIATLNRATFYAHFTDKEDLLDYTLSVTILKDLNDNLSISNVINEKVLRNIFISIASYIKDAAKSCELNSEAFCNKAHRRINNELEDIFAIMLENSYPEHQRDIIVNSASFLAAGISGLALHWFNTSQETADVFIDRNLPFLIHHIAHF
>NZ_CP047813.1|WP_001791985.1|2140135_2140264_+|hypothetical-protein
MDFKNEDKIKVYCNNMFEKLPISLSKNSEFCDILFFIVLSYR
>NZ_CP047813.1|WP_000200684.1|2140390_2141446_+|PTS-transporter-subunit-IIC
MTSIKTITPKDFIFRVLSGVAIGIVAGLVPNAILGEIFKYFMDYHPIFKTLLGVVVAIQFTVPALIGALVAMKFDLSPLAIAVVASAAYVGSGAAQFKNGAWMITGIGDLINTMITAAIAVLFILLIQHRVGSMALIVFPTVVGGISGAIGVLILPYTKMITTAIGNMVNGFTELQPIVMSILISMVFSLIIISPLSTVAIAFAIGITGLAAGSASIGISATEAVLIIGTSKVNRLGVPLSVFFGGVKMMIPNMVKYPILMLPILTTAIVSGLVSALVGIHGTKESAGFGFIGMVGPINAFKFMEVDSAWLSVLLIVVAFFVVPFVTAWLADIIYRKVFRLYTNDIFKFMG
>NZ_CP047813.1|WP_000751267.1|2142053_2142755_+|lytic-transglycosylase-IsaA
MKKTIMASSLAVALGVTGYAAGTGHQAHAAEVNVDQAHLVDLAHNHQDQLNAAPIKDGAYDIHFVKDGFQYNFTSNGTTWSWSYEAANGQTAGFSNVAGADYTTSYNQGSNVQSVSYNAQSSNSNVEAVSAPTYHNYSTSTTSSSVRLSNGNTAGATGSSAAQIMAQRTGVSASTWAAIIARESNGQVNAYNPSGASGLFQTMPGWGPTNTVDQQINAAVKAYKAQGLGAWGF
>NZ_CP047813.1|WP_000379825.1|2143441_2145253_+|O-acetyltransferase-OatA
MDTKDFKRLEKMYSPRYLPGLDGLRAFAVIGIIIYHLNAQWLSGGFLGVDTFFVISGYLITSLLISEYYRTQKIDLLEFWKRRLKRLIPAVLFLICVVLTFTLIFKPELIIQMKRDAIAAIFYVSNWWYISQNVDYFNQFAIEPLKHLWSLAIEEQFYLLFPLVITFLLHRFKPRNIIQTLFIVSLISLGLMIVIHFITGDNSRVYFGTDTRLQTLLLGCILAFIWPPFALKKDISKKIVVSLDIIGISGFAVLMTLFFIVGDQDQWIYNGGFYIISFATLFIIAIAVHPSSLFAKFLSMKPLLIIGKRSYSLYLWHYPIIVFVNSYYVQGQIPVYVYIIEILLTALMAEISYRFIETPIRKKGFKAFAFLPKKKSQFARTVLVILLLIPSIIVLSGQFDALGKQHEAEKKEKKTEFKTTKKKVVKKDKQEDKQTANSKEDIKKSSPLLIGDSVMVDIGNVFTKKIPNAQIDGKVGRQLVDATPIVKSQYKDYAKKGQKVVVELGTNGAFTKDQLNELLDSFGKADIYLVSIRVPRDYEGRINKLIYEAAEKRSNVHLVDWYKASAGHPEYFAYDGIHLEYAGSKALTDLIVKTMETHATNKK
>NZ_CP047813.1|WP_043044908.1|2145613_2146381_+|CHAP-domain-containing-protein
MKKIVTATIATAGLATIAFAGHDAQAAEQNNNGYNSNDAQSYSYTYTIDAQGNYHYTWTGNWNPSQLTQNNTYYYNNYNTYSYNNASYNNYYNHSYQYNNYTNNSQTATNNYYTGGSGASYSTTSNNVHVTTTAAPSSNGRSISNGYASGSNLYTSGQCTYYVFDRVGGKIGSTWGNASNWASAAASSGYTVNNTPKVGAIMQTTQGYYGHVAYVEGVNSNGSVRVSEMNYGHGAGVVTSRTISANQAGSYNFIH
>NZ_CP047813.1|WP_001795496.1|2146555_2147044_+|glycosyl-4,4'-diaponeurosporenoate-acyltransferase
MKKYIKTAFFCSMYWLIVQLNIANLGTRIPDKYFRQKYIIFKSFNFEKHGKFWNKWFYVRKWKHKILDGHQLNQNIYDQRHLMTINTDEIEKMIIETKRAELIHWISILPVIIFNKGPRLVKYINIFYAMIANVPIIIVQRYNRPRLTQLLRILKRRGERHD
>NZ_CP047813.1|WP_000160458.1|2147036_2148530_+|NAD(P)/FAD-dependent-oxidoreductase
MTKHIIVIGGGLGGISAAIRMAQSGYSVSLYEQNNHIGGKVNRHESDGFGFDLGPSILTMPYIFEKLFEYSKKQMSDYVTIKRLPHQWRSFFPDGTTIDLYEGIKETGQHNAILSKQDIEELQNYLNYTRRIDRITEKGYFNYGLDTLSQIIKFHGPLNALINYDYVHTMQQAIDKRISNPYLRQMLGYFIKYVGSSSYDAPAVLSMLFHMQQEQGLWYVEGGIHHLANALEKLAREEGVTIHTGARVDNIKTYQRRVTGVRLDTGEFVKADYIISNMEVIPTYKYLLHLDTQRLNKLEREFEPASSGYVMHLGVACQYPQLAHHNFFFTENAYLNYQQVFHEKVLPDDPTIYLVNTNKTDHTQAPVGYENIKVLPHIPYIQDQPFTTEDYAKFRDKILDKLEKMGLTDLRKHIIYEDVWTPEDIEKNYRSNRGAIYGVVADKKKNKGFKFPKESQYFENLYFVGGSVNPGGGMPMVTLSGQQVADKINAREAKNRK

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Crispr_ID: NZ_CP047813_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047813_11

2219849-2219982

Orphan

Consensus_repeat	Method
TATTGAAGAAGATACAA	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP047813_11

>merge|NZ_CP047813|11|2219849-2219982|PILER-CR
TATTGAAGAAGATACAAACAAAGACAAACCTAATTATCAATTCGGTGGACACAACATTGTTGATTTTGAAGAAGATACACTTCCAAAAGTAAGCGGCCAAAATGAAGGTCAACAAACGATTGAAGAAGATACAA

>NZ_CP047813|11|1|2219849-2219982|PILER-CR
TATTGAAGAAGATACAA	ACAAAGACAAACCTAATTATCAATTCGGTGGACACAACATTGTTGA
TTTTGAAGAAGATACAC	TTCCAAAAGTAAGCGGCCAAAATGAAGGTCAACAAAC
GATTGAAGAAGATACAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047813.1\|WP_043044932.1\|2226790_2227099_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047813.1\|WP_000074006.1\|2212240_2213005_+\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133381
NZ_CP047813.1\|WP_072399375.1\|2216922_2217225_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047813.1\|WP_072399377.1\|2221175_2224052_+\|fibronectin-binding-protein-FnbB	unknown	unknown	gnl\|CDD\|371043
NZ_CP047813.1\|WP_043044930.1\|2213158_2213839_+\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224715
NZ_CP047813.1\|WP_043044928.1\|2208774_2210598_+\|FUSC-family-protein	unknown	unknown	gnl\|CDD\|224208
NZ_CP047813.1\|WP_000966098.1\|2225275_2226469_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340863
NZ_CP047813.1\|WP_043044934.1\|2229684_2231277_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380283
NZ_CP047813.1\|WP_072361956.1\|2226479_2226683_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047813.1\|WP_072399378.1\|2227788_2229597_-\|phospho-sugar-mutase	unknown	unknown	gnl\|CDD\|100092
NZ_CP047813.1\|WP_000876661.1\|2213862_2215416_+\|gluconokinase	unknown	unknown	gnl\|CDD\|130381
NZ_CP047813.1\|WP_043044936.1\|2233115_2233901_+\|tandem-type-lipoprotein	unknown	unknown	gnl\|CDD\|367972
NZ_CP047813.1\|WP_043044927.1\|2205430_2206042_-\|DedA-family-protein	unknown	unknown	gnl\|CDD\|223659
NZ_CP047813.1\|WP_001117060.1\|2210736_2211153_+\|DUF2188-domain-containing-protein	unknown	unknown	gnl\|CDD\|227213
NZ_CP047813.1\|WP_000289136.1\|2211383_2212076_+\|GTP-pyrophosphokinase-family-protein	unknown	unknown	gnl\|CDD\|225232
NZ_CP047813.1\|WP_000660709.1\|2206588_2207866_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340877
NZ_CP047813.1\|WP_000481425.1\|2215532_2216891_+\|gluconate-permease	unknown	unknown	gnl\|CDD\|129873
NZ_CP047813.1\|WP_043044935.1\|2231346_2232555_+\|DNA-cytosine-methyltransferase	unknown	unknown	gnl\|CDD\|273211
NZ_CP047813.1\|WP_000721336.1\|2224231_2225098_+\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	unknown	unknown	gnl\|CDD\|224131
NZ_CP047813.1\|WP_000678764.1\|2227238_2227505_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP047813.1\|WP_000074006.1\|2212240_2213005_+\|MerR-family-transcriptional-regulator	gnl\|CDD\|133381	cd01106, HTH_TipAL-Mta, Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA. Helix-turn-helix (HTH) TipAL, Mta, and SkgA transcription regulators, and related proteins, N-terminal domain. TipAL regulates resistance to and activation by numerous cyclic thiopeptide antibiotics, such as thiostrepton. Mta is a global transcriptional regulator; the N-terminal DNA-binding domain of Mta interacts directly with the promoters of mta, bmr, blt, and ydfK, and induces transcription of these multidrug-efflux transport genes. SkgA has been shown to control stationary-phase expression of catalase-peroxidase in Caulobacter crescentus. These proteins are comprised of distinct domains that harbor an N-terminal active (DNA-binding) site and a regulatory (effector-binding) site. The conserved N-terminal domain of these transcription regulators contains winged HTH motifs that mediate DNA binding. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. Unique to this family, is a TipAL-like, lineage specific Bacilli subgroup, which has five conserved cysteines in the C-terminus of the protein.	3.94707e-33
NZ_CP047813.1\|WP_072399377.1\|2221175_2224052_+\|fibronectin-binding-protein-FnbB	gnl\|CDD\|371043	pfam10425, SdrG_C_C, C-terminus of bacterial fibrinogen-binding adhesin. This is the C-terminal half of a bacterial fibrinogen-binding adhesin SdrG. SdrG is a Gram-positive cell-wall-anchored adhesin that allows attachment of the bacterium to host tissues via specific binding to the beta-chain of human fibrinogen (Fg). SdrG binds to its ligand with a dynamic "dock, lock, and latch" mechanism which represents a general mode of ligand-binding for structurally related cell wall-anchored proteins in most Gram-positive bacteria. The C-terminal part of SdrG(276-596) is integral to the folding of the immunoglobulin-like whole to create the docking grooves necessary for Fg binding. The domain is associated with families of Cna_B, pfam05738.	1.72599e-33
NZ_CP047813.1\|WP_043044930.1\|2213158_2213839_+\|GntR-family-transcriptional-regulator	gnl\|CDD\|224715	COG1802, GntR, Transcriptional regulators [Transcription].	8.20029e-43
NZ_CP047813.1\|WP_043044928.1\|2208774_2210598_+\|FUSC-family-protein	gnl\|CDD\|224208	COG1289, COG1289, Predicted membrane protein [Function unknown].	1.99102e-88
NZ_CP047813.1\|WP_000966098.1\|2225275_2226469_+\|MFS-transporter	gnl\|CDD\|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	7.77868e-57
NZ_CP047813.1\|WP_043044934.1\|2229684_2231277_+\|hypothetical-protein	gnl\|CDD\|380283	NF033441, BREX_BrxC, BREX system P-loop protein BrxC. BrxC is a P-loop-containing protein, and probable ATPase, from BREX (bacteriophage exclusion) systems of type 1.	0.00673009
NZ_CP047813.1\|WP_072399378.1\|2227788_2229597_-\|phospho-sugar-mutase	gnl\|CDD\|100092	cd05799, PGM2, This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphopentoses. PGM2L1 is thought to catalyze the 1,3-bisphosphoglycerate-dependent synthesis of glucose 1,6-bisphosphate and other aldose-bisphosphates that serve as cofactors for several sugar phosphomutases and possibly also as regulators of glycolytic enzymes. PGM2 and PGM2L1 belong to the alpha-D-phosphohexomutase superfamily which includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Other members of this superfamily include phosphoglucosamine mutase (PNGM), phosphoacetylglucosamine mutase (PAGM), the bacterial phosphomannomutase ManB, the bacterial phosphoglucosamine mutase GlmM, and the bifunctional phosphomannomutase/phosphoglucomutase (PMM/PGM). Each of these enzymes has four domains with a centrally located active site formed by four loops, one from each domain. All four domains are included in this alignment model.	0
NZ_CP047813.1\|WP_000876661.1\|2213862_2215416_+\|gluconokinase	gnl\|CDD\|130381	TIGR01314, gntK_FGGY, gluconate kinase, FGGY type. Gluconate is derived from glucose in two steps. This model describes one form of gluconate kinase, belonging to the FGGY family of carbohydrate kinases. Gluconate kinase phosphoryates gluconate for entry into the Entner-Douderoff pathway. [Energy metabolism, Sugars].	0
NZ_CP047813.1\|WP_043044936.1\|2233115_2233901_+\|tandem-type-lipoprotein	gnl\|CDD\|367972	pfam04507, DUF576, Csa1 family. This family contains several uncharacterized staphylococcal proteins. These proteins have been called conserved staphylococcal antigens (Csa).	1.65486e-132
NZ_CP047813.1\|WP_043044927.1\|2205430_2206042_-\|DedA-family-protein	gnl\|CDD\|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	1.96902e-42
NZ_CP047813.1\|WP_001117060.1\|2210736_2211153_+\|DUF2188-domain-containing-protein	gnl\|CDD\|227213	COG4876, COG4876, Uncharacterized protein conserved in bacteria [Function unknown].	1.25256e-62
NZ_CP047813.1\|WP_000289136.1\|2211383_2212076_+\|GTP-pyrophosphokinase-family-protein	gnl\|CDD\|225232	COG2357, COG2357, PpGpp synthetase catalytic domain [General function prediction only].	8.50652e-86
NZ_CP047813.1\|WP_000660709.1\|2206588_2207866_+\|MFS-transporter	gnl\|CDD\|340877	cd17319, MFS_ExuT_GudP_like, Hexuronate transporter, Glucarate transporter, and similar transporters of the Major Facilitator Superfamily. This family is composed of predominantly bacterial transporters for hexuronate (ExuT), glucarate (GudP), galactarate (GarP), and galactonate (DgoT). They mediate the uptake of these compounds into the cell. They belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.24287e-91
NZ_CP047813.1\|WP_000481425.1\|2215532_2216891_+\|gluconate-permease	gnl\|CDD\|129873	TIGR00791, Gluconate_permease, gluconate transporter. This family includes known gluconate transporters of E. coli and Bacillus species as well as an idonate transporter from E. coli. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	2.53789e-168
NZ_CP047813.1\|WP_043044935.1\|2231346_2232555_+\|DNA-cytosine-methyltransferase	gnl\|CDD\|273211	TIGR00675, Modification_methylase, DNA-methyltransferase (dcm). All proteins in this family for which functions are known are DNA-cytosine methyltransferases. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair].	1.42169e-115
NZ_CP047813.1\|WP_000721336.1\|2224231_2225098_+\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	gnl\|CDD\|224131	COG1210, GalU, UDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane].	8.48908e-177

>NZ_CP047813.1|WP_072399375.1|2216922_2217225_+|hypothetical-protein
MQYIALKHVYFYAKNRLKWSESERYKKYIGYFSVMKGVSRHVFVRIVQAIIMKRLVYCFKLDNDEFNLKNKYKKYKPCVTRVYDDLNTIYRYISNNKIIN
>NZ_CP047813.1|WP_000481425.1|2215532_2216891_+|gluconate-permease
MFNEIWPLISVVLGIVILLVLIIGFKLNTFISLIITSMITALMLGIPLTKIMETIEKGMGSTLGHIALIFGLGAILGKLLADGGGATRIADTLIQKFGQKHVQWAMLVAAFIVGIALFFEVGLVLLIPLVFTVAKRANVSVLKLGLPMVTALSVTHGFLPPHPGPVVIAKELKANVGDVLLYGMIIAIPVTLIAGPIFNKVAQKMIPSAYTREGDISALGAQKEFTDQEMPGFGMSLLTATLPVILMLVSTITQLVTGHDKPTNLFESIIYMIGTAGTAMLIAVLFAIVTMGLMRKRKMNHIMESVTNAIYPIGMMLLIIGGGGTFKQVLIDGGVGNTIAKMFEGTEMSPILLAWIVAAVLRIALGSATVAAISTTGIVLPLLQSSDVNVALVVLAIGAGSVILSHVNDAGFWMFKEYFGLTVKETFLTWSLLETIISVSGIIFILFISLFV
>NZ_CP047813.1|WP_000876661.1|2213862_2215416_+|gluconokinase
MKYMIGVDIGTTSTKSVLYDENGTFIMKHQIGYDLHTPNVDVSEENPDELFDAVLMTIKYVMRESKVNKDDIKFVSFSAQMHSLIAMDQKHQRLTNNITWADNRAAKYATVINEVHDGNAIYQRTGTPIHPMSPLVKIFWMKHEWQDVFQRTAKFADIKTYIFYHLFDTYIIDYSMASATGMFNLETLDWDVGALELLGISKEMLPELVPTTYVMKGMKERYATLMGLNEDTPFVIGASDGVLSNLGVNSVGKGEVAVTIGTSGAIRTVIDKPRTDYKGRIFCYVLTEDHYVIGGPVNNGGVVLRWLRDELLASEVETAKRLGVDPYDVLTQIAKRVKPGADGLIFHPYLAGERAPLWNANARGSFFGLTLSHKKEHMIRAALEGVLYNLYTVYLALIEVMNETPKMIKATGGFAKSEVWRQMMSDIFDTELVVPESYESSCLGACVLGLKAVGDIEDFSIVSSMVGATNNHMPFEENVAVYQELVSIFINLSRSLTENYEQIADFQRQHMAENKTQ
>NZ_CP047813.1|WP_043044930.1|2213158_2213839_+|GntR-family-transcriptional-regulator
MMYGYPEKWLEGMTTGEGIAAELRLGIVNGHIAEGTLLTENQMAKQFNVSRSPIRDAFKLLQQNQLIQLERMGAHVLPFGEQEKKEMYDLRLMLESFAFSRVKNQERLPIVKEMKKQLEMMKVAVKFEDAESFTKHDFEFHETLIKASIHQYLNSFWSHLKPVMMALVLTSMRQRMQQNPQDFERIHHNHQVFIDAVEQYDSQILKEAFHLNFDDVGKDIEGFWLN
>NZ_CP047813.1|WP_000074006.1|2212240_2213005_+|MerR-family-transcriptional-regulator
MSNYSTGELAKLCNVTTRTIQYYDRKGILKPQGFTEGKRRVYTEQQRQTLELILLLKDLGCALSDIDMLLKGEGTLKTLNTLLTMKQQEINQQVKQQQAVLNKIKNVQYYVNEASTSPITHLKDIEHVMSKSAEMKSIRRNIWISAGIIGIIQYSSIISAILMKNKWPFLIALPFMICYGIGVTFYYQQKVAYLCPNCQHIFSPSLWQVIKAKHTATTRRFECPNCHETHYCIEVPKAHKSTEQLEISHIQHNN
>NZ_CP047813.1|WP_000289136.1|2211383_2212076_+|GTP-pyrophosphokinase-family-protein
MYVDRKPSLYLEDLRHDFKNSLSKFENGDEAFDTLLGFVELDHIYSSALKEISTKLSILDDNFNHIYKHNPIHHMERRVKEMRSLIEKLNRKGLQISAETAKEHILDIAGIRVVCNYLDDIYLIEEMLLKQEDVQLIKRKDYIQHPKENGYRSLHIVVSIPVFLAERVEVLPVEIQIRTIGMDMWASLEHKIRYKNNAETEKYRDLLKECATEITEVEDKLQQIHSEITE
>NZ_CP047813.1|WP_001117060.1|2210736_2211153_+|DUF2188-domain-containing-protein
MPFTMKGYPEKWKEFEVIKRQKAIEIANAMLKEGYLEKDVVPIAVKKAKDWYRALSKEEIKALEEENFVQFHTATMEKTEVDSEYATTDNEEHIQEQSNQDKSYFDSESIGNQSGGVRQREPLMDGPHPKVVESFKDV
>NZ_CP047813.1|WP_043044928.1|2208774_2210598_+|FUSC-family-protein
MIIPAIIGYLCGNFQFGLLVATGTLAHIYVFKGPSRSKLRTVIICNLAFAICMMLGTLTAKTPLVFGMTLLIVTVIPFYIFTALKIAGPSSTFFIVTFSLPINLPIAPEEALYRGFAILVGGILATMMVLITIVFSKNKAEEQAIQNDFKLISKLLHTYNDKSAFLQVAKTAVDSFKVSDKLLITSTSSNDKLSRRFQKLLLLHTSAQGIYSELLELNAKQIRPLPDELIEMMDYIIAQLDNSEENVRYWRKEVTVTEEFQNLFNHILKIDEMVHANEARIAYEADMRKPLYSKRIYQNLTLDSIVFRNTLRYTAIMMIAIFIALMFNFEKAYWIPLSAHTILLGTSTIHAIERGMARGLGTILGVLVLSVILLFSIPTPIAVILMGIAALFTEALVGANYAIAVVFITIQVILMNGLASQNLTINIAFPRVIDVAMGIVIAIIGLFVLGQRTASALLPNVMAEVVRKEATLFHYLFSENQYKDDVYQKNTAMNLSVKLNNMTQVYNAANGELFSDKTLIQNYYPSLFALEEISFMLNRAMANEDRLTINEQLMGEYLATFENIAKHFELNTGLEIKILPDLPQYNYIQSAMMNIQHNGFRERDKNV
>NZ_CP047813.1|WP_000660709.1|2206588_2207866_+|MFS-transporter
MKEKRTNVRWMFALAFFFIGVIAYMDRANISYIAKQMMDDLGMTKPQFGLLASFFSLGYALMQVPSGMLAEKFGPRKMITIALVWWSAFTILTGMIKNHGLIYLVRFLFGVGEAPMYPSNAVFNSFWFSKNEKGRASSALLAGSYFGPVLAPIVTIAIVNAFNWQAVFYIFGAVGILMAVLWAIIAKDLPEQHRMVNEAEKRFIMENRDIVATEKSSPPWNDFFKRFSFYAIAIQYFVVQFIITLFLIWLPTYLTEVFHVNFKEMSISSLPWLLMFFLILSAGAISDRVLGLGRSKFVARGVIAIAGFIVFAVSIIFAVRTGNLYVSIFWLSLGLGGIGISMGMSWAAATDLGRNFSGTVSGWMNLWGNIGALISPLLAGLFVEHLGWTMTFQLLIVPAVIAVIMWFYVKPDQPLIVSDDKAIEK
>NZ_CP047813.1|WP_043044927.1|2205430_2206042_-|DedA-family-protein
MEQIITEFISRFGYAAIFILILLENVLPIVPSEIILTFAGLMSVKSHLSILTLFIIATIASFIGLLILYYICRLISEERLYRFIDRHGKWIKLKSKDLKRANDWFKKYGVWAVFICRFIPVLRVLITIPAGVNRMNVVTFTVISLIGTTIWNFGLILLGRTLSDSFGMLMAGLHTYSRIMYVVIIIAVIYFAIRYIGKRKRVK
>NZ_CP047813.1|WP_072399377.1|2221175_2224052_+|fibronectin-binding-protein-FnbB
MKSNLRYGIRKHKLGAASVFLGTMIVVGMGQEKEAAASEQNNTTVEESGSSATERKASETQTTTNNVNTIDETQSYSATSTEQPSQSTQVTTEEAPTTVQAPKVETSRVDLPSEKVADKETTGTQVDTAQPSNVSEIKPRMKRSADGAVVPEKEVVEETKATGIDVTSKVKVEEGSEIVGHNNKETNVVNPHNAERVTLKYKWKFEDGIKPGDYFDFTLSNNVETHGISTLRKVPEIKSSDGQVMAVGEVNEERKIRYTFKEYVQGKKDLKAELDLNLFIDPTTVTKRGNQNIEVTLGEKKTSKQFDIKYLDGVKDNWGVTVNGRIHTLNKEEGRFSHFAYVKPNNQSLTSVTVSGQVTKGNKSGASNPSVKVYKHIGSDELAESVYGDVLDETKFEDVTDKLSLTLTGNGGYTLDFSELDKTKNYVIKYEGDYDSSASDLNFQTKLSGYHNYYYSYYPVQLTWNNGVAFYSNNAKGDGKDKPNDPIIEKSEPIDLDIKSEPPVEKHELTGTIEESNDSKPIDFEYHTAVEGAEGHAEGIIETEEDSIHVDFEESTHENSKHHADVVEYEEDTNPGGGQVTTESNLVEFDEESTKGIVTGAVSDHTTIEDTKEYTTESNLIELVDELLEEHGQAQGPIEEITENNNHISHSGLGTENGHGNYGVIEEIEENSHVDIKSELGYEGGQNSGNQSFEEDTEEDKPKYEQGGNIVDIDFDSVPQIHGQNNGDQSFEEDTEKDKPKYEQGGNIIDIDFDSVPHIHGFNKHNEIIEEDTNKDKPNYQFGGHNSVDFEEDTLPQVSGHNEGQQTIEEDTTPPIVPPTPPTPEVPSEPETPTPPTPEVPSEPETPTPPTPEVPSEPGTPVPPTPEVPTEPGKPVPPAKEEPKKPSKPVEQGKVVTPVIEINEKVKAVAPTKQKQSKKSELPETGGEESTNKGMLFGGLFSILGLALLRRNKKNHKV
>NZ_CP047813.1|WP_000721336.1|2224231_2225098_+|UTP--glucose-1-phosphate-uridylyltransferase-GalU
MKKIKKAIIPAAGLGTRFLPATKAMPKEMLPILDKPTIQYIVEEAARAGIEDIIIVTGRHKRAIEDHFDSQKELEMVLKEKGKSELLEKVQYSTELANIFYVRQKEQKGLGHAISSARQFIGNEPFAVLLGDDIVESEVPAVKQLIDVYEETGHSVIGVQEVPEADTHRYGIIDPLTKNGRQYEVKKFVEKPAQGTAPSNLAIMGRYVLTPEIFDYLKTQKEGAGNEIQLTDAIERMNNDNQVYAYDFEGERYDVGEKLGFVKTTIEYALKDDSMREELTRFIKALGL
>NZ_CP047813.1|WP_000966098.1|2225275_2226469_+|MFS-transporter
MLYLEVLKNRNFTYLLIGNFLRRSCFVLFSLQIIWFTVELTNQSSLKLSMMVMSQTLPFIIFGIFGGAYSDKHNKKKILYLSDLILSLIIIIIPLLAITSNLNYLTLLTISTAITIINCYTDPAFRAILPEIIDEEHLATSNALIDSLQRGSNIILPALIGVIVILVGNVGVFFICSILLFLGFIFNALLKYTNNNMIDRHSKEDFSETWEFLKQSKEIPFIIIIQFACILINTGLWRVALPLFISNILKEGVGVYGLATSCLGIASLLMSLIMGLLSEKRLIFKFSIGVLVWGIGLSIINVFPSVAILYIGATLVGLGQSIEGLTRSVAIQIKTPNHLMGKVFSISSTSNYAADTLSLGLISLIIPLLSLSNIFISGGAIISMLSLSGLKFFKKSM
>NZ_CP047813.1|WP_072361956.1|2226479_2226683_+|hypothetical-protein
MLINAIKVGIEMKYKISLAYNLAIIIGSLIILCILISRGHDIYVILIPILTVLASLINLFCDIKKHK
>NZ_CP047813.1|WP_043044932.1|2226790_2227099_-|hypothetical-protein
MTVNIVFSIVFCISMVILGIYVAITKDFTLISFINQTTIADNHKNQIAYIFALCISLSAVFLMSSILCFEYDFIALAFLFLTIALLLIALFYVCFYKITKYP
>NZ_CP047813.1|WP_000678764.1|2227238_2227505_-|hypothetical-protein
MKGSKQILLIMGIISLIVLFIFTLFIMAQYAKHYEQKSDSSNAHTLNSSSAIIEQHTMSNLASLDLYAPVRNITSSRDIHPIYFMTKD
>NZ_CP047813.1|WP_072399378.1|2227788_2229597_-|phospho-sugar-mutase
MHFHTHLLYNTCEKYCLGAVFFYFWGVFLYNSLHKCKGFSFHVLLSLTEILKGCLATMDKELWIERANDSLVKHFYEQQSDIEQREGFESKLTFGTAGIRGKFGLGEGRLNKFTIEKLALGLARYLNAQTNSPTIVIHYDIRHLSTEFAQIIANVLANHQITVYLPDTYKTTPELSFAVRNLNTTAGIMITASHNPKDYNGIKVYGSDGAQLSTDASELVSRYIEDVGDPLQIDISFSKHNSSYIKPLPKSVAENYIKHIQNMIGYIPKSDLQVVFTSLHGTSVPIVPKLLKSLNFNQFNLVETQCKPDPNFSSVQSANPEDHRAFDQAVELANKSHADLLISTDPDADRLGIAERNAHGHITYFNGNQIGALLLNYRIQQTSQLRHRLMIQSIVSSELTKSLARYNNVKYKEVLTGFKFIAQEIRQLDDHQNMIFAFEESYGFLSEPFVRDKDAVQIVPLIIKYASELKLYGKTLKDELEQIYQTVGRHEDTLFSHTLEGLEGKKKINAIMTKFRSNPPQEIQGLKVKAIEDYLTSEVYHLDKDTTSQINSPKSNVIRVLFDEGFIALRPSGTEPKIKLYVSLKCPNFDDVAQKINAMIFS
>NZ_CP047813.1|WP_043044934.1|2229684_2231277_+|hypothetical-protein
MWSNLKDEDKKTYRKLITNFASLSEAFSQKNESKEGGEDIVAPIVNSKFQETVFQRAFGAIGEDIANTSYDASLLLDDKHKYLVGIKSFGITSGDQKIAQFKKNSQFDNWGRILNEIQKNAQMVNSKEEANEINEYLYKELAIKIARLRNARIESSKEQIKGFKGTDNTVEAVYHVLMPSKKGQKPQIHVGETDYKPIDIDNLEIIGATTKNNPTNFKFTDNNHEYKYTSADSQLYMAFNNRDIVVESWDVNYINDPFDLFEKLNEQVNQGVLEKKYKDEEILKTISWVIYDENGNIPTNSGFNAFNGGSKLGLSTRAKRINKIYDEYKSKVSEEKIKKVKNLLEEVLLKKWSTDEEKEIMMKIRDELSELLVEIKNIDLIEEVEKLIYRPIREMYIPIPNSKKFHESNPDFFGHDIGRFKVNSSKLLLPKEDRTFKLKFLSSGDVIEAYINQDAGKSIQSYKNQQILGEWILQGVFQLAPREILTGDKLNDIGINGIRLIKFKDGTIGLEFIWIDIENPPDDVIGWVGK
>NZ_CP047813.1|WP_043044935.1|2231346_2232555_+|DNA-cytosine-methyltransferase
MTDSVSSNDASKYSLAAFFSGVGGIELGFHQTNKFRVVYANEFDKNAQITYENNFNNVSLDCRDIHDVKTSEIPMSDVIVGGFPCQAFSIAGYQKGFEDERGDLFFELLRFINEKSPQAIFIENVKNMVTHDHGNTFKVIKEALTLNGYFIKWKVLNAKDYGDIPQNRERIYIVGFKCRKAFDLFEFPEKIDLKTGIKDIINFESEIDERYYYRMNKQPFYDELEKEMKDSNLIYQWRRRYVRANKSGVVPTLTANMGTGGHNVPLIKSKFGIRKLTPRETFSVQGFPESFKLPDNMSNGQLYKQAGNSVVVPVVKRIAENIAESLDNSELPVFKLDIKSKYVLLYTKMIGRFEGESYILNGFDSENDLNKFIRKHKINFITEEEYKKVMKSNVGKEYYTLK
>NZ_CP047813.1|WP_043044936.1|2233115_2233901_+|tandem-type-lipoprotein
MIHSKKLTLGICLVLLIILIGGYVIMTKENGRNAQIKEAFNKTLKVYPTKNLDDFYDKEGFRDQEFDKRDKGTWIIYSEMVIEPKGKNMETRGMVLYINRNTRTTKGNFIVNEITDDNDGRPIDNKKKYPVKMEHNKIIPTKPLPNDKLKKEIENFKFFVQYGNFKDINDYKDGDISYNPNVPSYSAKYQLNNDDYNVQQLRKRYDIPTKQAPKLLLKGDGDLKGSSVGSRSLEFTFVENKEENIFFTDSVEFTPSEVDKS

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Crispr_ID: NZ_CP047813_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047813_12

2292829-2292907

Orphan

Consensus_repeat	Method
TGCAAGTTGGCGGAGCCCCAACA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP047813_12

>merge|NZ_CP047813|12|2292829-2292907|CRISPRCasFinder
TGCAAGTTGGCGGAGCCCCAACACAGTAGCTGGCGGAAAGTCAGCTTACAATAATGTGCAAGTTGGCGGAGCCCCAACA

>NZ_CP047813|12|10|2292829-2292907|CRISPRCasFinder
TGCAAGTTGGCGGAGCCCCAACA	CAGTAGCTGGCGGAAAGTCAGCTTACAATAATG
TGCAAGTTGGCGGAGCCCCAACA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047813.1\|WP_001176863.1\|2290471_2291614_-\|glycerate-kinase	unknown	unknown	gnl\|CDD\|272872
NZ_CP047813.1\|WP_043044953.1\|2293212_2294976_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP047813.1\|WP_001080281.1\|2286994_2287651_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227323
NZ_CP047813.1\|WP_000971550.1\|2300195_2301311_+\|pyridoxal-phosphate-dependent-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|223234
NZ_CP047813.1\|WP_001185692.1\|2282214_2284293_-\|sodium:proton-antiporter	unknown	unknown	gnl\|CDD\|223104
NZ_CP047813.1\|WP_000200954.1\|2302024_2302492_+\|QueT-transporter-family-protein	unknown	unknown	gnl\|CDD\|377623
NZ_CP047813.1\|WP_000482647.1\|2292401_2292509_+\|type-I-toxin-antitoxin-system-Fst-family-toxin	unknown	unknown	unknown
NZ_CP047813.1\|WP_043044952.1\|2289752_2290412_-\|membrane-protein	unknown	unknown	unknown
NZ_CP047813.1\|WP_000783428.1\|2302543_2303521_-\|bi-component-gamma-hemolysin-HlgAB/HlgCB-subunit-B	unknown	unknown	gnl\|CDD\|273388
NZ_CP047813.1\|WP_043044951.1\|2287763_2288237_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|226231
NZ_CP047813.1\|WP_001192075.1\|2288359_2289571_-\|multidrug-effflux-MFS-transporter	unknown	unknown	gnl\|CDD\|340878
NZ_CP047813.1\|WP_001789205.1\|2296964_2297132_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047813.1\|WP_000690199.1\|2286125_2286932_+\|phosphohydrolase	unknown	unknown	gnl\|CDD\|163441
NZ_CP047813.1\|WP_001217913.1\|2297186_2297873_+\|dethiobiotin-synthase	unknown	unknown	gnl\|CDD\|223210
NZ_CP047813.1\|WP_001046645.1\|2299210_2300218_+\|biotin-synthase-BioB	unknown	unknown	gnl\|CDD\|235755
NZ_CP047813.1\|WP_043044956.1\|2297850_2299209_+\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	unknown	unknown	gnl\|CDD\|273109
NZ_CP047813.1\|WP_000286875.1\|2301321_2302014_+\|6-carboxyhexanoate--CoA-ligase	unknown	unknown	gnl\|CDD\|224342
NZ_CP047813.1\|WP_000101538.1\|2284430_2285840_-\|amino-acid-permease	unknown	unknown	gnl\|CDD\|224038
NZ_CP047813.1\|WP_160186742.1\|2295000_2296734_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP047813.1\|WP_000779357.1\|2291881_2292268_+\|GtrA-family-protein	unknown	unknown	gnl\|CDD\|225155

Protein	Function_ID	Function_description	E-value
NZ_CP047813.1\|WP_001176863.1\|2290471_2291614_-\|glycerate-kinase	gnl\|CDD\|272872	TIGR00045, Glycerate_kinase, glycerate kinase. The only characterized member of this family so far is the glycerate kinase GlxK (EC 2.7.1.31) of E. coli. This enzyme acts after glyoxylate carboligase and 2-hydroxy-3-oxopropionate reductase (tartronate semialdehyde reductase) in the conversion of glyoxylate to 3-phosphoglycerate (the D-glycerate pathway) as a part of allantoin degradation. [Energy metabolism, Other].	0
NZ_CP047813.1\|WP_043044951.1\|2287763_2288237_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|226231	COG3708, COG3708, Uncharacterized protein conserved in bacteria [Function unknown].	5.35124e-37
NZ_CP047813.1\|WP_001080281.1\|2286994_2287651_-\|hypothetical-protein	gnl\|CDD\|227323	COG4990, COG4990, Uncharacterized protein conserved in bacteria [Function unknown].	2.51069e-72
NZ_CP047813.1\|WP_000971550.1\|2300195_2301311_+\|pyridoxal-phosphate-dependent-aminotransferase-family-protein	gnl\|CDD\|223234	COG0156, BioF, 7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism].	1.12947e-139
NZ_CP047813.1\|WP_000779357.1\|2291881_2292268_+\|GtrA-family-protein	gnl\|CDD\|225155	COG2246, COG2246, Predicted membrane protein [Function unknown].	2.13726e-22
NZ_CP047813.1\|WP_000200954.1\|2302024_2302492_+\|QueT-transporter-family-protein	gnl\|CDD\|377623	pfam06177, QueT, QueT transporter. This family includes the queT gene encoding a hypothetical integral membrane protein with 5 predicted transmembrane regions. The queT genes in Firmicutes are often preceded by the PreQ1 (7-aminomethyl-7-deazaguanine) riboswitches of two distinct classes, suggesting involvement of the QueT transporters in uptake of a queuosine biosynthetic intermediate.	0.00118414
NZ_CP047813.1\|WP_160186742.1\|2295000_2296734_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.80822e-142
NZ_CP047813.1\|WP_001185692.1\|2282214_2284293_-\|sodium:proton-antiporter	gnl\|CDD\|223104	COG0025, NhaP, NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism].	2.07656e-103
NZ_CP047813.1\|WP_000783428.1\|2302543_2303521_-\|bi-component-gamma-hemolysin-HlgAB/HlgCB-subunit-B	gnl\|CDD\|273388	TIGR01002, synergohymenotropic_toxin, beta-channel forming cytolysin. This family of cytolytic pore-forming proteins includes alpha toxin and leukocidin F and S subunits from Staphylococcus aureus, hemolysin II of Bacillus cereus, and related toxins. [Cellular processes, Toxin production and resistance].	5.50766e-128
NZ_CP047813.1\|WP_043044953.1\|2293212_2294976_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	4.36176e-146
NZ_CP047813.1\|WP_001192075.1\|2288359_2289571_-\|multidrug-effflux-MFS-transporter	gnl\|CDD\|340878	cd17320, MFS_MdfA_MDR_like, Multidrug transporter MdfA and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as MdfA (also called chloramphenicol resistance pump Cmr), EmrD, MdtM, MdtL, bicyclomycin resistance protein (also called sulfonamide resistance protein), and the uncharacterized inner membrane transport protein YdhC. EmrD is a proton-dependent secondary transporter, first identified as an efflux pump for uncouplers of oxidative phosphorylation. It expels a range of drug molecules and amphipathic compounds across the inner membrane of E. coli. Similarly, MdfA is a secondary multidrug transporter that exports a broad spectrum of structurally and electrically dissimilar toxic compounds. These MDR transporters are drug/H+ antiporters (DHA) belonging to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.81144e-73
NZ_CP047813.1\|WP_000690199.1\|2286125_2286932_+\|phosphohydrolase	gnl\|CDD\|163441	TIGR03729, acc_ester, putative phosphoesterase. Members of this protein family belong to the larger family pfam00149 (calcineurin-like phosphoesterase), a family largely defined by small motifs of metal-chelating residues. The subfamily in this model shows a good but imperfect co-occurrence in species with domain TIGR03715 that defines a novel class of signal peptide typical of the accessory secretory system.	1.39132e-107
NZ_CP047813.1\|WP_001217913.1\|2297186_2297873_+\|dethiobiotin-synthase	gnl\|CDD\|223210	COG0132, BioD, Dethiobiotin synthetase [Coenzyme metabolism].	1.50939e-71
NZ_CP047813.1\|WP_001046645.1\|2299210_2300218_+\|biotin-synthase-BioB	gnl\|CDD\|235755	PRK06256, PRK06256, biotin synthase; Validated.	0
NZ_CP047813.1\|WP_000286875.1\|2301321_2302014_+\|6-carboxyhexanoate--CoA-ligase	gnl\|CDD\|224342	COG1424, BioW, Pimeloyl-CoA synthetase [Coenzyme metabolism].	1.03044e-132
NZ_CP047813.1\|WP_000101538.1\|2284430_2285840_-\|amino-acid-permease	gnl\|CDD\|224038	COG1113, AnsP, Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism].	0
NZ_CP047813.1\|WP_043044956.1\|2297850_2299209_+\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	gnl\|CDD\|273109	TIGR00508, hypothetical_protein_DESPIG_00326, adenosylmethionine-8-amino-7-oxononanoate transaminase. All members of the seed alignment have been demonstrated experimentally to act as EC 2.6.1.62, an enzyme in the biotin biosynthetic pathway. Alternate names include 7,8-diaminopelargonic acid aminotransferase, DAPA aminotransferase, and adenosylmethionine-8-amino-7-oxononanoate aminotransferase. The gene symbol is bioA in E. coli and BIO3 in S. cerevisiae. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin].	0

>NZ_CP047813.1|WP_000482647.1|2292401_2292509_+|type-I-toxin-antitoxin-system-Fst-family-toxin
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK
>NZ_CP047813.1|WP_000779357.1|2291881_2292268_+|GtrA-family-protein
MKLTQTHAEILKFIIVGGINTLNYYVVYLLLLKLLHIEYMISHITGFLVAFMISYYLNCYFVYRVKPTWRKFISFPITQIVNVSLQTVLLYVFVSWLNLPAEIAPFAGLVITIPITFVLSKWILKDSN
>NZ_CP047813.1|WP_001176863.1|2290471_2291614_-|glycerate-kinase
MQLQKIVIAPDSFKESMTAQQVGNIIKQAFTNVYGNTLHYDIIPMADGGEGTTDALMHATGATKYTVIVNDPLMRPIEACYARADEQQIAIIEMAAASGLDLLEKEERNPLYTSSYGTGELIKDALNHGAKTIILGIGGSATNDGGTGMLSALGVKFTDVNGDLLQMNGANLAHIAQIDITNLDSRLKEVTFKVACDVSNPLLGENGATYIYGPQKGADAKMIPKLDFAMSHYHDKIKMCTGKSVNQIPGSGAAGGMGAALLAFCETTLTKGIDVVFDITDFHQRIKDADLVITGEGRMDYQTIFGKTPVGVALAAKQYHIPVIAICGSLGENYQHVYDFGIDSAYSIISSPSTLEDVLQNSEQNLLNTATDIARILKLQ
>NZ_CP047813.1|WP_043044952.1|2289752_2290412_-|membrane-protein
MKRTDKYRDSYQYDNQNQNHRRQSEDASFRQQYAKGDPEEHPERYYNGRDYRREQILEEENEKSRRSKKWLYIIIAILLIIVAIFVTRALLNNDSDKVSNDPKVSQNYKKQVENQDGQINQQVDNAKENIKNNQKTDDIIKNLQNQIDNLKQQEQNKADSKLTQFYQDQINKLTEANNALKNNASQGKIESMLNDINTKFDSIKSKLESLFKDDNGGAN
>NZ_CP047813.1|WP_001192075.1|2288359_2289571_-|multidrug-effflux-MFS-transporter
MQSTKTKTKHFSFLLLITLGVMTAFGPLTIDMYVPSLPKVQGDFGSTTSEIQLTLSFTMIGLALGQFIFGPLSDAFGRKRIAVSILIIFILVSGLSMFVDQLPLFLTLRFIQGLTGGGVIVIAKASAGDKFSGNALAKFLASLMVVNGIITILAPLAGGLALSVATWRSIFTILTIVALIILIGVASQLPKTSKDELKQVNFSSVIKDFGSLLKKPAFIIPMLLQGLTYVMLFSYSSASPFITQKLYNMTPQQFSIMFAVNGVGLIIVSQVVALLVEKLHRHILLIILTIIQVVGVALIILTLTFHLPLWVLLIAFFLNVCPVTSIGPLGFTMAMEERTGGSGNASSLLGLFQFILGGAVAPLVGLKGEFNTSPYMIIIFITAILLVSLQIIYFKMIKKQHVA
>NZ_CP047813.1|WP_043044951.1|2287763_2288237_+|AraC-family-transcriptional-regulator
MEYQLQQLASLTLVGIKETYENGRQAQQHIARFWQRCYQEGVIADLQLKNNGDLAGILGLCIPELDGKMSYMIAVTGDNSADIEKYDVITLASSKYMVFEAQGAVPKAVQQKMEEVHHYIHQYQADTVKSAPFFELYQDGDTTSEKYITEIWMPVKG
>NZ_CP047813.1|WP_001080281.1|2286994_2287651_-|hypothetical-protein
MNRKILPVKPISQLFPIPMVMGCEGVSAAMMLQYNNQHIPATEIMRHWPTHPNNPHKGYVGHHLFIKLGNYHQTIFPEAYVPFLQKYNPNIVDGTGKSLEDLKGIIDQGQPVLIYHTNLGSKPLLRVFRFDNKPAKQVSNIHVTLLIGYDDYYYYYIDPLWSHIRRGLVLPAIIPNRKQIIKIRKEKMEYSFNSPGRKCIYVQPHSYTIENQQQNKHT
>NZ_CP047813.1|WP_000690199.1|2286125_2286932_+|phosphohydrolase
MKIGTIADLHIDRHNKKTSEDYLEALVEIVKYKKLDILLIAGDISNHYQLTHQFITQLTKQLDIPVKFVPGNHDLWEVESMTTQDIWNNYKSMSQCLVGKPFIVNEEWAIIGHTGWYDYSFAAQRFSLEHLQKGKHYGATWQDKERISWGISDQNLSKIAAEQVKKDILEVGNRRVILVTHVVTHPDFIVPMPHRIFDFYNAFIGTSDFNPLYAMFDIPYSIMGHVHFRKSVIDDGRCYLCPCLGYPRQWRSEDIYQEINETIQIIEI
>NZ_CP047813.1|WP_000101538.1|2284430_2285840_-|amino-acid-permease
MARKLHRELNNRHIQLIAIGGAIGTGLFLGSGQTISLTGPSLLFTYMIIGVVLFAFMRALGELLLSNTRFNSFVDIANEYLGPFGGFVIGWTYWLCWIVSSMSDLTAMGQYFAFWYPQVPNWITVLFIVLILISFNLLGARLFGELEFWFSIIKVVTIIAMVIVGLVLIFFSFKTHYGHASFTNLISHGGMFPGGTFGFLMSFQIAVYSFIGIELIGVTAGETKDPEKTLPKAINNVPIRILLFYIGGLLVIMSVIPWNDIDPNSSPFVKLFTLIGVPFAAGVVNFVVLTAAASATNSGIYSNSRILFGLSQQGLGPKVLNKTNSHGVPYLSMLVSSIALLIAALLNYIFPNAIQLFIYVTTLSTVLFLVVWAMIIVAYLMYLKKHPEAHKNSKFKLIGGKPIAYIILAFFFFVFILLFFSDETRAAIYISPFWFIFLFFFYKKYKTNAEKLAYEQRQNDSGHFRYDNQ
>NZ_CP047813.1|WP_001185692.1|2282214_2284293_-|sodium:proton-antiporter
MALLEAFLIFIFAVIISSVINNRFPQIPTAFIQIALGVVIFIIPIQVDFQFNSEVFMFAVIAPLLFVEGTHVSRTKLLEYRKPILLMSMALVFATVVGVGYFIHWIWPALPMPAAFAIAAILCPTDAVAVSAITRGKLLPKGSMTILEGESLLNDAAGIISFKIAVTALVTGTFSLFQAVEQFIISTILGVLIGAIIGFVVVRIRIDLTANKGLKDNNTLTFIQLLTPFVVYFLAEEVHASGIIAVVIAGLIHGLERDRLIRAQTELQMNYHQIWNTFSYALNGFVFVVLGFMIPTVVIDIFQTEPDNFSFLIVITILIAIAIYACRFVWVYFWYKDFYFPKNIQSYLDEEHDSHETPPSRVRYAFIMTMCGIHGTISLSMALTLPFIITKGQAFEYRNDLLFIASFMVLISLILAQIVLPLITPSAEDTTFKGMTYQSAKIFIVQKVIQHFKNESKKDKNDTNYRPVLNQYYGELLFLLNSEPDNQNTKELKRLEDIAKVIETSTLERLIDKGKATYQDINNYRNIVELTETHRTASFVEKFANFFKMLWLRLKAMKHYKALNKESKKQEFENSFKDVQKIMRIVNHNIILRLKEEQNSTNVLEVSLVINHYYDMSRSLKWRAQRRKERQENSNQIIPQAMFHNHKLEALYLQRHLLDELIRKNKINNIVAAQIRENINYNEIVLSLQSKH
>NZ_CP047813.1|WP_043044953.1|2293212_2294976_+|ABC-transporter-ATP-binding-protein
MNNQTNWIKILSGFASDSKWKIMLSILLSIISVFSGLVPYWAVFKIILMMINNAYTINSIMVYIFIALIAYISQVCCFGASTMLSHITAYEILSEIRKKLAQKLMRLPLGVVESKKIGELKNIFVDKVETIELPLAHMIPEVIGNLLLSAAIFLYIMLIDWRMASALLVTIPISIFAFKKVMSGFNETYAEQMKSNNYMNSAIVEFIEGIEVIKTFNQSQSSYKKYKDAVDNYKIHTLNWFKNTWGYMNLGASVLPSTFLGILPVGMYLISINQLNYAEFFLCIVLSLGVVAPIKNFTNYVNHLKSIQYALTEVNQILSLEELVLSTKFKKPQHYEIAFNNVGFSYNKDKDDLVFKHLSFTVPENNFIAIVGASGSGKSTIAKLISRYWDVTSGEITIGGINIKDIESKQLNDLVGFVGQDNFLLNLTFKENIKLGNPEATDEAVEKAAKLAQCHEFIEKLPDGYDTNVGTVGDKLSGGEKQRVTIARMILKDAPIIVLDEATAYVDPDNEQKIQEALNVLTQDKTLIVIAHRLSTIQHADQIIVLGKQQILEKGSHHLLLKLNGNYKKMWDTHMHTKDWGINTGHN
>NZ_CP047813.1|WP_160186742.1|2295000_2296734_+|ABC-transporter-ATP-binding-protein
MFQITFKILNWIRPYKARMILGFSMSFLNAIFIALPIFLAAKIFNNVLSHKPIYMKDILNVVIIMVLLVIGRFITAYFKSKSHESIAYEMSAKERLDIGDKLKNVRLGYFNSHHSNELITIVTTDLTFLENFAMKMVDVVVNGYILITVLILSLLVVSWQVSLLACIGVLLSFFAIQLLERKSRQNAPAYHNVQNQLVEKVLEVIRGIQVIKSFAKENTSLKSFNQAVNESKRINTKIEMQYIPFNLLHLLSLKVVSIMIVLVACLLYMNHSIDLPTLIMISIFSFVIFDSVENINSAAHVLEMIDMTIDDIEKIKNAPELDENGKNLTIKNENIAFQNVNFSYDDKQVIKNVNFEIPIQTSTAIIGPSGSGKSTLCHLLLRFYDIDDGNIRIDGVDIKDMTLSTLMSKISAVFQKVYLFNDTIENNILFGNPGATKEEIIRAAKQACCHDFIMSLPEGYQTMLNEKGSNLSGGEKQRISIARAILKDAPIIILDEATASIDPENEQLIQTAINELSKGKTVITIAHKLETIKNADQIIVLNEGEIIQKGSHDELIRKPGMYQDFIRIKSKSAGWKL
>NZ_CP047813.1|WP_001789205.1|2296964_2297132_+|hypothetical-protein
MQLLILTDIFYRIAVYICPNSVRSLSHFNSKVKILPKFIVILRSLNSCFLEKHAP
>NZ_CP047813.1|WP_001217913.1|2297186_2297873_+|dethiobiotin-synthase
MRIFITSTNTDVGKTYVTKHLYHALKTRGHRVCIFKPFQTEERQDGTFPDLEVFKNECDLSYDITSLYTFKQPVSPHLAFKMANQIFLNKQRVLDKVKVLDKEFDFILIEGAGGIAVPIYEGTDDFYMTKDLINDCADCVISVLPSKLGAISDAIVHQDYVNQNVSASNFLIMNRYTDSYIEKDNQITIGKLTNKTVYTFEEHATYENFSEAFLKQLIGVKNELHTTT
>NZ_CP047813.1|WP_043044956.1|2297850_2299209_+|adenosylmethionine--8-amino-7-oxononanoate-transaminase
MNYTQQLKQKDSEYVWHPFTQMGVYSKEEAIIIEKGKGSYLYDTNGNKYLDGYASLWVNVHGHNNKYLNKVIKKQLNKIAHSTLLGSSNIPSIELAEKLIEITPSNLRKVFYSDTGSASVEIAIKMAYQYWKNIDREKYAKKNKFITLNHGYHGDTIGAVSVGGIKTFHKIFKDLIFENIQVESPSFYRSNYDTENEMMTAILTNIEQILIERNDEIAGFILEPLIQGATGLFVHPKGFLKEVEKLCKKYDILLICDEVAVGFGRTGKMFACNHEDVQPDIMCLGKAITGGYLPLAATLTSQKIYNAFLSDSHGVNTFFHGHTYTGNQIVCTVALENIRLYEKRKLLSHIETTSSTLEKQLHALKRHRNVGDVRGRGLMFGVELVTDKDSKTPLEIEKVERIVRKCKENGLMIRNLENVITFVPVLSMSNKEVKTMVRIFKKAVHNILDRKC
>NZ_CP047813.1|WP_001046645.1|2299210_2300218_+|biotin-synthase-BioB
MNLAKRILQGEQLTKETVLKIYEDTNIDTLDLLNEAYILRKHYFGKKVKLNMILNAKSGICPENCGYCGQSRDIKQKQRYALIPEEQIIDGAKVAHDNHIGTYCIVMSGRGPSDKEVDHISNTVRTIKSQHPQLKICACLGLTNDEQAKKLKSAGVDRYNHNINTSENYHDNVVTTHSYKDRTDTIELMKANNISPCSGVICGMGESNQDIVDMAFALKEMDADSIPINFLHPIKGTKFGSMDDLTPMKCLRIVALFRLINPTKEIRIAGGREVNLRSLQPLALKAANSIFVGDYLITGGQPNQLDYDMINDLGFEIDYDTCENKENKNDVSRAN
>NZ_CP047813.1|WP_000971550.1|2300195_2301311_+|pyridoxal-phosphate-dependent-aminotransferase-family-protein
MMFQEQIDLLQQKGLYRSLKSVGYIDRQYIEVENKRCTNYTSNDYLGLGQIAFDKDDFERFMRKYSYHLSSSRLISGSSTAYEEIETMLAGWLGYSACTILNSGYDANLALFNIFKNTNCVVFSDQENHASIIDGIKLSGLEKVIYKHLDIADLEKRLEKYPNQNIPKIIISDSVFSTNGDVVDIGQLVSLKHKYNATLILDVSHSFGIENYSNYQGVDILTSSLSKACGAYGGVILSSNDVKDMLINHGRPLIYSSSLPIYNLYFIKRNIEKLINADDRRTKLNSLSKYFNQKLKALNVNYNSSNSPIKFIEFDDIEAAENIHQTLLKHHVFTSYLRYPTVTKPMLRISLSYFHTEQDIDRLFEILHQED
>NZ_CP047813.1|WP_000286875.1|2301321_2302014_+|6-carboxyhexanoate--CoA-ligase
MYSIKMRSSNQDVHISGAETICEFDKIEQTVQRFYNKGFFHENGQPDFLNIKIQKIMEPIQQIKALQIIEDDKANLQHLTQECGVTEQALNQGMTYIKNETVYTGAIILSAISGKRLDSFGQRGIRATHFSFEDINNKGDLNERVTDALAIASCINAHPYVKGELCVSDDLTYTTGYFAAAKIGYHRLFDIKPVNTRYGGRIIFVDDCIDLNHYISFLESTPKQVVYETV
>NZ_CP047813.1|WP_000200954.1|2302024_2302492_+|QueT-transporter-family-protein
MTSKDITQISVIAAILTILAVLKIPSIIPGLDFQLSAPAALLILAFFGIKKYFLGGLLSSVLLLIFGVFNPINVIISIIFRVIAIAVVYLLKINVLSLVLASVLGSLVSRLLLSIILNLPVWVVLLNAIPGVIFTLIVAIPLYLTLRKRMAVLLR
>NZ_CP047813.1|WP_000783428.1|2302543_2303521_-|bi-component-gamma-hemolysin-HlgAB/HlgCB-subunit-B
MKMNKLVKSSVATSMALLLLSGTANAEGKITPVSVKKVDDKVTLYKTTATADSDKFKISQILTFNFIKDKSYDKDTLVLKATGNINSGFVKPNPNDYDFSKLYWGAKYNVSISSQSNDSVNVVDYAPKNQNEEFQVQNTLGYTFGGDISISNGLSGGLNGNTAFSETINYKQESYRTTLSRNTNYKNVGWGVEAHKIMNNGWGPYGRDSFHPTYGNELFLAGRQSSAYAGQNFIAQHQMPLLSRSNFNPEFLSVLSHRQDGAKKSKITVTYQREMDLYQIRWNGFYWAGANYKNFKTRTFKSTYEIDWENHKVKLLDTKETENNK

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Crispr_ID: NZ_CP047813_13

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047813_13

2566473-2566558

Orphan

Consensus_repeat	Method
ACTAATGATACGCAAACATCAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP047813_13

>merge|NZ_CP047813|13|2566473-2566558|CRISPRCasFinder
ACTAATGATACGCAAACATCAGTTGGCCCAGTTGCAAACAATAAAGCTAAAGATATGCAAACTAATGATACGCAAAAATCAGTTGG

>NZ_CP047813|13|11|2566473-2566558|CRISPRCasFinder
ACTAATGATACGCAAACATCAGTTGG	CCCAGTTGCAAACAATAAAGCTAAAGATATGCAA
ACTAATGATACGCAAAAATCAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047813.1\|WP_001792784.1\|2577520_2577679_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047813.1\|WP_000167867.1\|2554845_2555754_+\|arginase	unknown	unknown	gnl\|CDD\|212515
NZ_CP047813.1\|WP_000047255.1\|2543001_2543685_+\|hemolysin-III-family-protein	unknown	unknown	gnl\|CDD\|224191
NZ_CP047813.1\|WP_000370925.1\|2576005_2576863_+\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|223635
NZ_CP047813.1\|WP_043044046.1\|2556753_2557686_+\|YbbR-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|227193
NZ_CP047813.1\|WP_160186749.1\|2546101_2547544_+\|multidrug-efflux-MFS-transporter-LmrS	unknown	unknown	gnl\|CDD\|129794
NZ_CP047813.1\|WP_001802298.1\|2578358_2578463_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047813.1\|WP_000495682.1\|2578961_2580053_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047813.1\|WP_000347896.1\|2555942_2556752_+\|TIGR00159-family-protein	unknown	unknown	gnl\|CDD\|224539
NZ_CP047813.1\|WP_000334463.1\|2573118_2574924_+\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NZ_CP047813.1\|WP_043044043.1\|2567180_2568287_-\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
NZ_CP047813.1\|WP_043044040.1\|2575155_2575938_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
NZ_CP047813.1\|WP_000636857.1\|2545305_2545779_+\|multidrug-efflux-transporter-SepA	unknown	unknown	gnl\|CDD\|374975
NZ_CP047813.1\|WP_001292149.1\|2568286_2568721_-\|mannitol-specific-phosphotransferase-enzyme-IIA-component	unknown	unknown	gnl\|CDD\|227014
NZ_CP047813.1\|WP_043044042.1\|2568732_2570865_-\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_CP047813.1\|WP_043045039.1\|2547691_2548756_+\|P-loop-NTPase	unknown	unknown	gnl\|CDD\|378455
NZ_CP047813.1\|WP_043045036.1\|2541795_2542983_+\|UDPGP-type-1-family-protein	unknown	unknown	gnl\|CDD\|133036
NZ_CP047813.1\|WP_043044041.1\|2570905_2572438_-\|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl\|CDD\|225123
NZ_CP047813.1\|WP_000521495.1\|2557712_2559068_+\|phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670
NZ_CP047813.1\|WP_023914005.1\|2543863_2545207_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794

Protein	Function_ID	Function_description	E-value
NZ_CP047813.1\|WP_000167867.1\|2554845_2555754_+\|arginase	gnl\|CDD\|212515	cd09989, Arginase, Arginase family. This family includes arginase, also known as arginase-like amidino hydrolase family, and related proteins. Arginase is a binuclear Mn-dependent metalloenzyme and catalyzes hydrolysis of L-arginine to L-ornithine and urea (Arg, EC 3.5.3.1), the reaction being the fifth and final step in the urea cycle, providing the path for the disposal of nitrogenous compounds. Arginase controls cellular levels of arginine and ornithine which are involved in protein biosynthesis, and in production of creatine, polyamines, proline and nitric acid. In vertebrates, at least two isozymes have been identified: type I (ARG1) cytoplasmic or hepatic liver-type arginase and type II (ARG2) mitochondrial or non-hepatic arginase. Point mutations in human arginase ARG1 gene lead to hyperargininemia with consequent mental disorders, retarded development and early death. Hyperargininemia is associated with a several-fold increase in the activity of the mitochondrial arginase (ARG2), causing persistent ureagenesis in patients. ARG2 overexpression plays a critical role in the pathophysiology of cholesterol mediated endothelial dysfunction. Thus, arginase is a therapeutic target to treat asthma, erectile dysfunction, atherosclerosis and cancer.	9.8301e-146
NZ_CP047813.1\|WP_000047255.1\|2543001_2543685_+\|hemolysin-III-family-protein	gnl\|CDD\|224191	COG1272, COG1272, Predicted membrane protein, hemolysin III homolog [General function prediction only].	2.41003e-66
NZ_CP047813.1\|WP_000370925.1\|2576005_2576863_+\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	6.8047e-59
NZ_CP047813.1\|WP_043044046.1\|2556753_2557686_+\|YbbR-like-domain-containing-protein	gnl\|CDD\|227193	COG4856, COG4856, Uncharacterized protein conserved in bacteria [Function unknown].	1.06774e-117
NZ_CP047813.1\|WP_160186749.1\|2546101_2547544_+\|multidrug-efflux-MFS-transporter-LmrS	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	4.71763e-82
NZ_CP047813.1\|WP_000347896.1\|2555942_2556752_+\|TIGR00159-family-protein	gnl\|CDD\|224539	COG1624, COG1624, Uncharacterized conserved protein [Function unknown].	2.13611e-103
NZ_CP047813.1\|WP_000334463.1\|2573118_2574924_+\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NZ_CP047813.1\|WP_043044043.1\|2567180_2568287_-\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
NZ_CP047813.1\|WP_043044040.1\|2575155_2575938_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	3.73928e-106
NZ_CP047813.1\|WP_000636857.1\|2545305_2545779_+\|multidrug-efflux-transporter-SepA	gnl\|CDD\|374975	pfam17080, SepA, Multidrug Resistance efflux pump. SepA is a drug efflux protein that is involved in bacterial multidrug resistance. It is predicted to have four transmembrane domains.	3.20059e-30
NZ_CP047813.1\|WP_001292149.1\|2568286_2568721_-\|mannitol-specific-phosphotransferase-enzyme-IIA-component	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
NZ_CP047813.1\|WP_043044042.1\|2568732_2570865_-\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	4.97106e-68
NZ_CP047813.1\|WP_043045039.1\|2547691_2548756_+\|P-loop-NTPase	gnl\|CDD\|378455	pfam10609, ParA, NUBPL iron-transfer P-loop NTPase. This family contains ATPases involved in plasmid partitioning. It also contains the cytosolic Fe-S cluster assembling factor NBP35 which is required for biogenesis and export of both ribosomal subunits.	2.87873e-114
NZ_CP047813.1\|WP_043045036.1\|2541795_2542983_+\|UDPGP-type-1-family-protein	gnl\|CDD\|133036	cd04193, UDPGlcNAc_PPase, UDPGlcNAc pyrophosphorylase catalayzes the synthesis of UDPGlcNAc. UDP-N-acetylglucosamine (UDPGlcNAc) pyrophosphorylase (UAP) (also named GlcNAc1P uridyltransferase), catalyzes the reversible conversion of UTP and GlcNAc1 to PPi and UDPGlcNAc. UDP-N-acetylglucosamine (UDPGlcNAc), the activated form of GlcNAc, is a key precursor of N- and O-linked glycosylations. It is essential for the synthesis of chitin (a major component of the fungal cell wall) and of the glycosylphosphatidylinositol (GPI) linker which anchors a variety of cell surface proteins to the plasma membrane. In bacteria, UDPGlcNAc represents an essential precursor for both peptidoglycan and lipopolysaccharide biosynthesis. Human UAP has two isoforms, resulting from alternative splicing of a single gene and differing by the presence or absence of 17 amino acids. UDPGlcNAc pyrophosphorylase shares significant sequence and structure conservation with UDPglucose pyrophosphorylase.	3.10048e-149
NZ_CP047813.1\|WP_043044041.1\|2570905_2572438_-\|PTS-mannitol-transporter-subunit-IICB	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
NZ_CP047813.1\|WP_000521495.1\|2557712_2559068_+\|phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0
NZ_CP047813.1\|WP_023914005.1\|2543863_2545207_+\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	2.9938e-43

>NZ_CP047813.1|WP_000521495.1|2557712_2559068_+|phosphoglucosamine-mutase
MGKYFGTDGVRGVANQELTPELAFKLGRYGGYVLAHNKGEKHPRVLVGRDTRVSGEMLESALIAGLISIGAEVMRLGIISTPGVAYLTRDMGAELGVMISASHNPVADNGIKFFGSDGFKLSDEQENEIEALLDQENPELPRPVGNDIVHYSDYFEGAQKYLSYLKSTVDVNFEGLKIVLDGANGSTSSLAPFLFGDLEADTETIGCSPDGYNINEKCGSTHPEKLAEKVVETESDFGLAFDGDGDRIIAVDENGQIVDGDQIMFIIGQEMHKNQELNNDMIVSTVMSNLGFYKALEQEGIKSNKTKVGDRYVVEEMRRGNYNLGGEQSGHIVMMDYNTTGDGLLTGIQLASVIKMTGKSLSELAGQMKKYPQSLINVRVTDKYRVEENVDVKEVMTKVEVEMNGEGRILVRPSGTEPLVRVMVEAATDEDAERFAQQIADVVQDKMGLDK
>NZ_CP047813.1|WP_043044046.1|2556753_2557686_+|YbbR-like-domain-containing-protein
MLESKWGLRFIAFLLALFFFLSVNNVFGNIFNTGNLGQKSSKTIQDVPVEILYNTKDLHLTKAPETVNVTISGPQSKIIKIENPEDLRVVIDLSNAKAGKYQEKYQVKGLADDIHYSVKPKLANITLENKVTKKMTVQPDVSQSDIDPLYKITKQEVSPQTVKVTGGEEQLNDIAYLKATFKTNKKINGDTKDVAEVAAFDKKLNKLNVSIQPNEVNLQVKVEPFSKKVKVNVKQKGSLADDKELSSIDLEDKEIEIFGSRDDLQNISEVDAEVDLDGISESTEKTVKINLPEHVTKAQPSETKAYINVK
>NZ_CP047813.1|WP_000347896.1|2555942_2556752_+|TIGR00159-family-protein
MDFSNFFQNLSTLKIVTSILDLLIVWYVLYLLITVFKGTKAIQLLKGILVIVIGQQISMILNLTATSKLFDIVIQWGVLALIVIFQPEIRRALEQLGRGSFLKRYTSNTYSKDEEKLIQSVSKAVQYMAKRRIGALIVFEKETGLQDYIETGIAMDSNISQELLINVFIPNTPLHDGAMIIQGTKIAAAASYLPLSDSPKISKSLGTRHRAAVGISEVSDAFTVIVSEETGDISVTFDGKLRRDISNEIFEELLAEHWFGTRFQKKGVK
>NZ_CP047813.1|WP_000167867.1|2554845_2555754_+|arginase
MTKTKAIDIIGAPSTFGQRKLGVDLGPTAIRYAGLISRLKQLDLDVYDKGDIKVPAVNIEKFHSEQKGLRNYDEIIDVNQKLNKEVSASIENNRFPLVLGGDHSIAVGSVSAISKHYNNLGVIWYDAHGDLNIPEESPSGNIHGMPLRILTGEGPKELLELNSNVIKPENIVLIGMRDLDKGERQFIKDHNIKTFTMSDIDKLGIKEVIENTIEYLKSRNVDGVHLSLDVDALDPLETPGTGTRVLGGLSYRESHFALELLHQSHLISSMDLVEVNPLIDSNNHTAEQAVSLVGTFFGETLL
>NZ_CP047813.1|WP_043045039.1|2547691_2548756_+|P-loop-NTPase
MLTVDQVKELVGEIKDPIIDVPLKETEGIVEVSIKEEKEHVSVKLAMAQLGGAPQLDLQMAVVNALKENGAKTVGIRFETLPEEKVNQFKPKEENKPKTIEGLLSQNNPVEFIAIASGKGGVGKSTVAVNLAVALAREGKKVGLVDTDIYGFSVPDMMGIDEKPGIKGKEVIPVERHGVKVISMAFFVEENAPVIWRGPMLGKMLTNFFTEVKWGDIEYLILDLPPGTGDVALDVHTMLPSSKEIIVTTPHPTAAFVAARAGAMAKHTDHSILGVIENMSYFESKETGKKEYVFGKGGGTKLADELNTQLLGELPLEQPSWNPKDFAPSIYQSDDRLGKIYSSIAQKVIAATNK
>NZ_CP047813.1|WP_160186749.1|2546101_2547544_+|multidrug-efflux-MFS-transporter-LmrS
MAKVELTTRRRNFIVAVMLISAFVAILNQTLLNTALPSIMRELNINESTSQWLVTGFMLVNGVMIPLTAYLMDRIKTRPLYLAAMGTFLLGSIVAALAPNFGVLMLARVIQAMGAGVLMPLMQFTLFTLFSKEHRGFAMGLAGLVIQFAPAIGPTVTGLIIDQASWRVPFIIIVGIALVAFVFGLVSISRYNEVKYTKLDKRSVMYSTIGFGLMLYAFSSAGDLGFTSPIVIGALIISMVIIYLFIRRQFNITNALLNLRVFKNRTFALCTISSMIIMMSMVGPALLIPLYVQNSLSLSALLSGLVIMPGAIINGIMSVFTGKFYDKYGPRPLIYTGFTILTITTIMLCFLHTDTSYTYLIVVYAIRMFSVSLLMMPINTTGINSLRNEEISHGTAIMNFGRVMAGSLGTALMVTLMSFGAKIFLSTSPSHLTATEIKQQSIAIGVDISFAFVAVLVMAAYVIALFIREPKEIESNRRKF
>NZ_CP047813.1|WP_000636857.1|2545305_2545779_+|multidrug-efflux-transporter-SepA
MIVNYLKHKFYNLLTTMIVLFIFVLSGAIFLTFLGFGLYGLSRILIYFRLGDFTYNRSMYDNLLYYGSYIIFGYFIIFAVEHLMDYFRKMLPENAYFRGATFHLISYTVATTLFYFIIHLNYVYINIDFWVIMVIIGFLYVCKLQFYPESKNLNNRK
>NZ_CP047813.1|WP_023914005.1|2543863_2545207_+|MFS-transporter
MRLKSIITVIALILIMFMSAIESSIISLALPTIKQDLNAGNLISLIFTAYFIALVIANPIVGELLSRFKIIYVAIAGLLLFSIGSFMCGLSTNFTMLIISRVIQGFGSGVLMSLSQIVPKLAFEIPLRYKIMGIVGSVWGISSIIGPLLGGGILEFATWHWLFYINIPIAIIAIILVIWTFHFPEEETVAKSKFDTKGLTLFYVFIGLIMFALLNQQLLLFNFLSFILAIVVAMCLFKVEKHVSSPFLPVVEFNRSITLVFITDLLTAICLMGFNLYIPVYLQEQLGLSPLQSGLVIFPLSVAWITLNFNLHRIEAKLSRKVIYLLSFTLLLVSSIIISFGIKLPVLIAFVLILAGLSFGYIYTKDSVIVQEETSPLQMKKMMSFYGLTKNLGASIGSTIMGYLYAIQSGIFGPNLHNVLSAVAVISIGLIVLWVVFFKEQSSQSKE
>NZ_CP047813.1|WP_000047255.1|2543001_2543685_+|hemolysin-III-family-protein
MSKSTKKSNDTIVETFKDIIPLSFGEEIGNAASHGVAALLTLLVLPYAAVHSYIAHGTLASVSMSIYVISIFMMFISSTIYHSMQNETPHKYILRIIDHSMIYVAISGTYTPILLTVVGGWIGWTVFILLWGTTLWGILYKSIAVKVNQKLSLIVYLVMGWVGIILLPIIFIRTSWIFILFIFLGGVSYTIGAWFYAQKNRPYFHMIWHIFIVIASLLHLIAILYFM
>NZ_CP047813.1|WP_043045036.1|2541795_2542983_+|UDPGP-type-1-family-protein
MLDKNQLAKYKQDHLCEYEKIMSNNEKEALEEKVASLDLDFIAKLYNDLYINKKTIDDVSAVSEVKYDIKSQMSDDEIKRLEEQGLQAIKEGQFAVLLMAGGQGTRLGYKGPKGSFEIEGVSLFELQANQLKTLNHQSGHTIQWYIMTSDINHEETLAYFEAHSYFGYDQEAIHFFKQDNIVALSEEGKLILNQQGRIMETPNGNGGVFKSLDKAGYLEEMSNNGVKYIFLNNIDNVLVRVLDPLFAGFTVEHDYDITSKTIQPKPGESVGRLVNVDCKDTVLEYSELDPEVANQFNNANIGIHAFKLGFILNAVNRELPYHLAIKNLKQLDENFGVIEQPTLKFELFYFDIFTYGTSFVTLQVPREEEFSPLKNKEGKDSVVTATEDLRRMGLI
>NZ_CP047813.1|WP_043044043.1|2567180_2568287_-|mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYSGKFAGKATVLDAVEDSSIEAGLRRVLAETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
>NZ_CP047813.1|WP_001292149.1|2568286_2568721_-|mannitol-specific-phosphotransferase-enzyme-IIA-component
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>NZ_CP047813.1|WP_043044042.1|2568732_2570865_-|BglG-family-transcription-antiterminator
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGADSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDIDGNTSFENEQTSYLTSVFEKHLSDEKSEQLMHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDAINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLILPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>NZ_CP047813.1|WP_043044041.1|2570905_2572438_-|PTS-mannitol-transporter-subunit-IICB
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSLDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDD
>NZ_CP047813.1|WP_000334463.1|2573118_2574924_+|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEDGTPVVALATQENVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>NZ_CP047813.1|WP_043044040.1|2575155_2575938_+|ABC-transporter-ATP-binding-protein
MLIQLDQIGRMKQGKTILKNISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATTGGVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDDEVRNEAHQLLKLVEISAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLNILDSLSDSYPTLAMIYVTHFIEEITGNFTKILLLKDGESVQQGLIDDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>NZ_CP047813.1|WP_000370925.1|2576005_2576863_+|Cof-type-HAD-IIB-family-hydrolase
MDNVKAIFLDMDGTILHENNQASTYTKDVINQLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQITNLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIAHFGIHQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAKHFLAD
>NZ_CP047813.1|WP_001792784.1|2577520_2577679_-|hypothetical-protein
MSKSSDALFNSLTQSFELIEGVYNELVTDNLKIVMYKPRKESTSGRINRRFK
>NZ_CP047813.1|WP_001802298.1|2578358_2578463_+|hypothetical-protein
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
>NZ_CP047813.1|WP_000495682.1|2578961_2580053_-|hypothetical-protein
MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYVQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPIFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKNKKVVTEPKNTKVENDKVTTSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP047813_7	7.1\|1190792\|25\|NZ_CP047813\|CRISPRCasFinder	1190792-1190816	25	NZ_CP047813.1	78194-78218	0	1.0
NZ_CP047813_7	7.1\|1190792\|25\|NZ_CP047813\|CRISPRCasFinder	1190792-1190816	25	NZ_CP047813.1	402432-402456	0	1.0
NZ_CP047813_7	7.1\|1190792\|25\|NZ_CP047813\|CRISPRCasFinder	1190792-1190816	25	NZ_CP047813.1	953731-953755	0	1.0
NZ_CP047813_7	7.1\|1190792\|25\|NZ_CP047813\|CRISPRCasFinder	1190792-1190816	25	NZ_CP047813.1	1147408-1147432	0	1.0
NZ_CP047813_7	7.1\|1190792\|25\|NZ_CP047813\|CRISPRCasFinder	1190792-1190816	25	NZ_CP047813.1	1196229-1196253	0	1.0
NZ_CP047813_7	7.1\|1190792\|25\|NZ_CP047813\|CRISPRCasFinder	1190792-1190816	25	NZ_CP047813.1	1238559-1238583	0	1.0
NZ_CP047813_7	7.1\|1190792\|25\|NZ_CP047813\|CRISPRCasFinder	1190792-1190816	25	NZ_CP047813.1	2469532-2469556	0	1.0
NZ_CP047813_7	7.1\|1190792\|25\|NZ_CP047813\|CRISPRCasFinder	1190792-1190816	25	NZ_CP047813.1	670962-670986	0	1.0
NZ_CP047813_7	7.1\|1190792\|25\|NZ_CP047813\|CRISPRCasFinder	1190792-1190816	25	NZ_CP047813.1	1361846-1361870	0	1.0
NZ_CP047813_7	7.1\|1190792\|25\|NZ_CP047813\|CRISPRCasFinder	1190792-1190816	25	NZ_CP047813.1	1722223-1722247	0	1.0
NZ_CP047813_7	7.1\|1190792\|25\|NZ_CP047813\|CRISPRCasFinder	1190792-1190816	25	NZ_CP047813.1	1840484-1840508	0	1.0
NZ_CP047813_7	7.1\|1190792\|25\|NZ_CP047813\|CRISPRCasFinder	1190792-1190816	25	NZ_CP047813.1	1840541-1840565	0	1.0
NZ_CP047813_7	7.1\|1190792\|25\|NZ_CP047813\|CRISPRCasFinder	1190792-1190816	25	NZ_CP047813.1	1840598-1840622	0	1.0
NZ_CP047813_7	7.1\|1190792\|25\|NZ_CP047813\|CRISPRCasFinder	1190792-1190816	25	NZ_CP047813.1	2138038-2138062	0	1.0
NZ_CP047813_7	7.1\|1190792\|25\|NZ_CP047813\|CRISPRCasFinder	1190792-1190816	25	NZ_CP047813.1	2257094-2257118	0	1.0
NZ_CP047813_10	10.1\|2137989\|34\|NZ_CP047813\|CRISPRCasFinder	2137989-2138022	34	NZ_CP047813.1	670854-670887	0	1.0
NZ_CP047813_5	5.1\|1147448\|34\|NZ_CP047813\|CRISPRCasFinder	1147448-1147481	34	NZ_CP047813.1	670854-670887	1	0.971
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	NZ_CP047813.1	78193-78221	1	0.966
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	NZ_CP047813.1	402431-402459	1	0.966
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	NZ_CP047813.1	670959-670987	1	0.966
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	NZ_CP047813.1	953730-953758	1	0.966
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	NZ_CP047813.1	1147407-1147435	1	0.966
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	NZ_CP047813.1	1196228-1196256	1	0.966
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	NZ_CP047813.1	1238558-1238586	1	0.966
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	NZ_CP047813.1	1361843-1361871	1	0.966
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	NZ_CP047813.1	1722220-1722248	1	0.966
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	NZ_CP047813.1	1840481-1840509	1	0.966
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	NZ_CP047813.1	1840538-1840566	1	0.966
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	NZ_CP047813.1	1840595-1840623	1	0.966
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	NZ_CP047813.1	2138035-2138063	1	0.966
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	NZ_CP047813.1	2257091-2257119	1	0.966
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	NZ_CP047813.1	2469531-2469559	1	0.966
NZ_CP047813_7	7.1\|1190792\|25\|NZ_CP047813\|CRISPRCasFinder	1190792-1190816	25	NZ_CP047813.1	369712-369736	1	0.96
NZ_CP047813_7	7.1\|1190792\|25\|NZ_CP047813\|CRISPRCasFinder	1190792-1190816	25	NZ_CP047813.1	369945-369969	1	0.96
NZ_CP047813_7	7.1\|1190792\|25\|NZ_CP047813\|CRISPRCasFinder	1190792-1190816	25	NZ_CP047813.1	1078707-1078731	1	0.96
NZ_CP047813_7	7.1\|1190792\|25\|NZ_CP047813\|CRISPRCasFinder	1190792-1190816	25	NZ_CP047813.1	1361788-1361812	1	0.96
NZ_CP047813_1	1.1\|224868\|33\|NZ_CP047813\|CRISPRCasFinder	224868-224900	33	NZ_CP047813.1	369882-369914	2	0.939
NZ_CP047813_2	2.1\|879128\|26\|NZ_CP047813\|CRISPRCasFinder	879128-879153	26	NZ_CP047813.1	1227915-1227940	2	0.923
NZ_CP047813_2	2.1\|879128\|26\|NZ_CP047813\|CRISPRCasFinder	879128-879153	26	NZ_CP047813.1	2023451-2023476	2	0.923
NZ_CP047813_4	4.1\|1098314\|33\|NZ_CP047813\|CRISPRCasFinder	1098314-1098346	33	NZ_CP047813.1	1147144-1147176	2	0.939
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	NZ_CP047813.1	68844-68872	2	0.931
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	NZ_CP047813.1	224924-224952	2	0.931
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	NZ_CP047813.1	369711-369739	2	0.931
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	NZ_CP047813.1	369944-369972	2	0.931
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	NZ_CP047813.1	1078706-1078734	2	0.931
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	NZ_CP047813.1	1147081-1147109	2	0.931
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	NZ_CP047813.1	1361785-1361813	2	0.931
NZ_CP047813_9	9.1\|1722164\|33\|NZ_CP047813\|CRISPRCasFinder	1722164-1722196	33	NZ_CP047813.1	1227895-1227927	2	0.939
NZ_CP047813_9	9.1\|1722164\|33\|NZ_CP047813\|CRISPRCasFinder	1722164-1722196	33	NZ_CP047813.1	1361729-1361761	2	0.939
NZ_CP047813_9	9.1\|1722164\|33\|NZ_CP047813\|CRISPRCasFinder	1722164-1722196	33	NZ_CP047813.1	402370-402402	2	0.939
NZ_CP047813_10	10.1\|2137989\|34\|NZ_CP047813\|CRISPRCasFinder	2137989-2138022	34	NZ_CP047813.1	1840435-1840468	2	0.941
NZ_CP047813_12	12.1\|2292852\|33\|NZ_CP047813\|CRISPRCasFinder	2292852-2292884	33	NZ_CP047813.1	1722108-1722140	2	0.939
NZ_CP047813_12	12.1\|2292852\|33\|NZ_CP047813\|CRISPRCasFinder	2292852-2292884	33	NZ_CP047813.1	2682658-2682690	2	0.939

1. spacer 7.1|1190792|25|NZ_CP047813|CRISPRCasFinder matches to position: 78194-78218, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattctacagg	CRISPR spacer
gaatttcgaaaagaaattctacagg	Protospacer
*************************

2. spacer 7.1|1190792|25|NZ_CP047813|CRISPRCasFinder matches to position: 402432-402456, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattctacagg	CRISPR spacer
gaatttcgaaaagaaattctacagg	Protospacer
*************************

3. spacer 7.1|1190792|25|NZ_CP047813|CRISPRCasFinder matches to position: 953731-953755, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattctacagg	CRISPR spacer
gaatttcgaaaagaaattctacagg	Protospacer
*************************

4. spacer 7.1|1190792|25|NZ_CP047813|CRISPRCasFinder matches to position: 1147408-1147432, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattctacagg	CRISPR spacer
gaatttcgaaaagaaattctacagg	Protospacer
*************************

5. spacer 7.1|1190792|25|NZ_CP047813|CRISPRCasFinder matches to position: 1196229-1196253, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattctacagg	CRISPR spacer
gaatttcgaaaagaaattctacagg	Protospacer
*************************

6. spacer 7.1|1190792|25|NZ_CP047813|CRISPRCasFinder matches to position: 1238559-1238583, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattctacagg	CRISPR spacer
gaatttcgaaaagaaattctacagg	Protospacer
*************************

7. spacer 7.1|1190792|25|NZ_CP047813|CRISPRCasFinder matches to position: 2469532-2469556, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattctacagg	CRISPR spacer
gaatttcgaaaagaaattctacagg	Protospacer
*************************

8. spacer 7.1|1190792|25|NZ_CP047813|CRISPRCasFinder matches to position: 670962-670986, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattctacagg	CRISPR spacer
gaatttcgaaaagaaattctacagg	Protospacer
*************************

9. spacer 7.1|1190792|25|NZ_CP047813|CRISPRCasFinder matches to position: 1361846-1361870, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattctacagg	CRISPR spacer
gaatttcgaaaagaaattctacagg	Protospacer
*************************

10. spacer 7.1|1190792|25|NZ_CP047813|CRISPRCasFinder matches to position: 1722223-1722247, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattctacagg	CRISPR spacer
gaatttcgaaaagaaattctacagg	Protospacer
*************************

11. spacer 7.1|1190792|25|NZ_CP047813|CRISPRCasFinder matches to position: 1840484-1840508, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattctacagg	CRISPR spacer
gaatttcgaaaagaaattctacagg	Protospacer
*************************

12. spacer 7.1|1190792|25|NZ_CP047813|CRISPRCasFinder matches to position: 1840541-1840565, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattctacagg	CRISPR spacer
gaatttcgaaaagaaattctacagg	Protospacer
*************************

13. spacer 7.1|1190792|25|NZ_CP047813|CRISPRCasFinder matches to position: 1840598-1840622, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattctacagg	CRISPR spacer
gaatttcgaaaagaaattctacagg	Protospacer
*************************

14. spacer 7.1|1190792|25|NZ_CP047813|CRISPRCasFinder matches to position: 2138038-2138062, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattctacagg	CRISPR spacer
gaatttcgaaaagaaattctacagg	Protospacer
*************************

15. spacer 7.1|1190792|25|NZ_CP047813|CRISPRCasFinder matches to position: 2257094-2257118, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattctacagg	CRISPR spacer
gaatttcgaaaagaaattctacagg	Protospacer
*************************

16. spacer 10.1|2137989|34|NZ_CP047813|CRISPRCasFinder matches to position: 670854-670887, mismatch: 0, identity: 1.0

attgggaatccaatttctctttgttggggcccat	CRISPR spacer
attgggaatccaatttctctttgttggggcccat	Protospacer
**********************************

17. spacer 5.1|1147448|34|NZ_CP047813|CRISPRCasFinder matches to position: 670854-670887, mismatch: 1, identity: 0.971

atgggccccaacaaagagaaattggattctcaat	CRISPR spacer
atgggccccaacaaagagaaattggattcccaat	Protospacer
*****************************.****

18. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to position: 78193-78221, mismatch: 1, identity: 0.966

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
agaatttcgaaaagaaattctacaggcaa	Protospacer
************ ****************

19. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to position: 402431-402459, mismatch: 1, identity: 0.966

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
agaatttcgaaaagaaattctacaggcaa	Protospacer
************ ****************

20. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to position: 670959-670987, mismatch: 1, identity: 0.966

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
agaatttcgaaaagaaattctacaggcaa	Protospacer
************ ****************

21. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to position: 953730-953758, mismatch: 1, identity: 0.966

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
agaatttcgaaaagaaattctacaggcaa	Protospacer
************ ****************

22. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to position: 1147407-1147435, mismatch: 1, identity: 0.966

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
agaatttcgaaaagaaattctacaggcaa	Protospacer
************ ****************

23. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to position: 1196228-1196256, mismatch: 1, identity: 0.966

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
agaatttcgaaaagaaattctacaggcaa	Protospacer
************ ****************

24. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to position: 1238558-1238586, mismatch: 1, identity: 0.966

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
agaatttcgaaaagaaattctacaggcaa	Protospacer
************ ****************

25. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to position: 1361843-1361871, mismatch: 1, identity: 0.966

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
agaatttcgaaaagaaattctacaggcaa	Protospacer
************ ****************

26. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to position: 1722220-1722248, mismatch: 1, identity: 0.966

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
agaatttcgaaaagaaattctacaggcaa	Protospacer
************ ****************

27. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to position: 1840481-1840509, mismatch: 1, identity: 0.966

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
agaatttcgaaaagaaattctacaggcaa	Protospacer
************ ****************

28. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to position: 1840538-1840566, mismatch: 1, identity: 0.966

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
agaatttcgaaaagaaattctacaggcaa	Protospacer
************ ****************

29. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to position: 1840595-1840623, mismatch: 1, identity: 0.966

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
agaatttcgaaaagaaattctacaggcaa	Protospacer
************ ****************

30. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to position: 2138035-2138063, mismatch: 1, identity: 0.966

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
agaatttcgaaaagaaattctacaggcaa	Protospacer
************ ****************

31. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to position: 2257091-2257119, mismatch: 1, identity: 0.966

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
agaatttcgaaaagaaattctacaggcaa	Protospacer
************ ****************

32. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to position: 2469531-2469559, mismatch: 1, identity: 0.966

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
agaatttcgaaaagaaattctacaggcaa	Protospacer
************ ****************

33. spacer 7.1|1190792|25|NZ_CP047813|CRISPRCasFinder matches to position: 369712-369736, mismatch: 1, identity: 0.96

gaatttcgaaaagaaattctacagg	CRISPR spacer
gaatttcgtaaagaaattctacagg	Protospacer
******** ****************

34. spacer 7.1|1190792|25|NZ_CP047813|CRISPRCasFinder matches to position: 369945-369969, mismatch: 1, identity: 0.96

gaatttcgaaaagaaattctacagg	CRISPR spacer
gaatttcgtaaagaaattctacagg	Protospacer
******** ****************

35. spacer 7.1|1190792|25|NZ_CP047813|CRISPRCasFinder matches to position: 1078707-1078731, mismatch: 1, identity: 0.96

gaatttcgaaaagaaattctacagg	CRISPR spacer
gaatttctaaaagaaattctacagg	Protospacer
******* *****************

36. spacer 7.1|1190792|25|NZ_CP047813|CRISPRCasFinder matches to position: 1361788-1361812, mismatch: 1, identity: 0.96

gaatttcgaaaagaaattctacagg	CRISPR spacer
gaatttcaaaaagaaattctacagg	Protospacer
*******.*****************

37. spacer 1.1|224868|33|NZ_CP047813|CRISPRCasFinder matches to position: 369882-369914, mismatch: 2, identity: 0.939

cattattgaaagctgactattggccagcttcta	CRISPR spacer
cattattgaaagctgacttttggtcagcttcta	Protospacer
****************** ****.*********

38. spacer 2.1|879128|26|NZ_CP047813|CRISPRCasFinder matches to position: 1227915-1227940, mismatch: 2, identity: 0.923

ccaccagcttctatgttggggccccg	CRISPR spacer
ccgcctgcttctatgttggggccccg	Protospacer
**.** ********************

39. spacer 2.1|879128|26|NZ_CP047813|CRISPRCasFinder matches to position: 2023451-2023476, mismatch: 2, identity: 0.923

ccaccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctttgttggggccccg	Protospacer
**.********* *************

40. spacer 4.1|1098314|33|NZ_CP047813|CRISPRCasFinder matches to position: 1147144-1147176, mismatch: 2, identity: 0.939

ccaacttgcacactattgtaagctgactttcca	CRISPR spacer
ccaacttgcacattattgtaagctgacttacca	Protospacer
************.**************** ***

41. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to position: 68844-68872, mismatch: 2, identity: 0.931

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
agaatttcgaaaggaaattctacagacaa	Protospacer
************ ************.***

42. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to position: 224924-224952, mismatch: 2, identity: 0.931

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
agaatttcgaaaagaaattctacagacaa	Protospacer
************ ************.***

43. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to position: 369711-369739, mismatch: 2, identity: 0.931

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
agaatttcgtaaagaaattctacaggcaa	Protospacer
********* ** ****************

44. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to position: 369944-369972, mismatch: 2, identity: 0.931

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
agaatttcgtaaagaaattctacaggcaa	Protospacer
********* ** ****************

45. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to position: 1078706-1078734, mismatch: 2, identity: 0.931

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
agaatttctaaaagaaattctacaggcaa	Protospacer
******** *** ****************

46. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to position: 1147081-1147109, mismatch: 2, identity: 0.931

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
agaatttcgaaaagaaattctacagacaa	Protospacer
************ ************.***

47. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to position: 1361785-1361813, mismatch: 2, identity: 0.931

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
agaatttcaaaaagaaattctacaggcaa	Protospacer
********.*** ****************

48. spacer 9.1|1722164|33|NZ_CP047813|CRISPRCasFinder matches to position: 1227895-1227927, mismatch: 2, identity: 0.939

cattattgtaagctgactttccgccagcttcta	CRISPR spacer
cattattgttagctgactttccgcctgcttcta	Protospacer
********* *************** *******

49. spacer 9.1|1722164|33|NZ_CP047813|CRISPRCasFinder matches to position: 1361729-1361761, mismatch: 2, identity: 0.939

cattattgtaagctgactttccgccagcttcta	CRISPR spacer
cattattgtaagctgtcttttcgccagcttcta	Protospacer
*************** ****.************

50. spacer 9.1|1722164|33|NZ_CP047813|CRISPRCasFinder matches to position: 402370-402402, mismatch: 2, identity: 0.939

cattattgtaagctgactttccgccagcttcta	CRISPR spacer
cattattgtaagctgacttttcgtcagcttcta	Protospacer
********************.**.*********

51. spacer 10.1|2137989|34|NZ_CP047813|CRISPRCasFinder matches to position: 1840435-1840468, mismatch: 2, identity: 0.941

attgggaatccaatttctctttgttggggcccat	CRISPR spacer
attgggaatccaattcctttttgttggggcccat	Protospacer
***************.**.***************

52. spacer 12.1|2292852|33|NZ_CP047813|CRISPRCasFinder matches to position: 1722108-1722140, mismatch: 2, identity: 0.939

cagtagctggcggaaagtcagcttacaataatg	CRISPR spacer
cagaagctggcgaaaagtcagcttacaataatg	Protospacer
*** ********.********************

53. spacer 12.1|2292852|33|NZ_CP047813|CRISPRCasFinder matches to position: 2682658-2682690, mismatch: 2, identity: 0.939

cagtagctggcggaaagtcagcttacaataatg	CRISPR spacer
cagaggctggcggaaagtcagcttacaataatg	Protospacer
*** .****************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP047813_3	3.1\|998536\|22\|NZ_CP047813\|CRISPRCasFinder	998536-998557	22	NC_007021	Staphylococcus phage Twort, complete genome	4397-4418	2	0.909
NZ_CP047813_3	3.1\|998536\|22\|NZ_CP047813\|CRISPRCasFinder	998536-998557	22	MT151386	Staphylococcus virus Twort, complete genome	46926-46947	2	0.909
NZ_CP047813_8	8.3\|1353374\|27\|NZ_CP047813\|CRT	1353374-1353400	27	MT416612	Bacillus phage YungSlug, complete genome	7222-7248	5	0.815
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	NZ_LT984809	Cupriavidus taiwanensis isolate Cupriavidus taiwanensis STM 8555 plasmid I, complete sequence	102953-102981	6	0.793
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	NZ_CP045275	Bacillus megaterium strain FDU301 plasmid pFDU301C, complete sequence	4578-4606	7	0.759
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	MN655998	Escherichia phage E26, complete genome	123445-123473	8	0.724
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	MH560358	Escherichia virus KFS-EC, complete genome	67718-67746	8	0.724
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	MK573636	Escherichia phage vB_EcoM_PHB13, partial genome	111150-111178	8	0.724
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	MT764208	Escherichia phage JEP8, complete genome	37770-37798	8	0.724
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	MT478991	Escherichia phage vB_EcoM_011D4, complete genome	74685-74713	8	0.724
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	MK327941	Escherichia phage vB_EcoM_G37-3, complete genome	125624-125652	8	0.724
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	NC_009821	Enterobacteria phage Phi1, complete genome	123689-123717	8	0.724
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	MF327006	Shigella phage Sf20, complete genome	59751-59779	8	0.724
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	MK327932	Escherichia phage vB_EcoM_G2248, complete genome	130440-130468	8	0.724
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	NC_025425	Enterobacteria phage GEC-3S complete genome	123230-123258	8	0.724
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	MN709127	Escherichia virus Ec_Makalu_002, complete genome	124447-124475	8	0.724
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	MN732896	Elizabethkingia phage TCUEAP1, complete genome	46961-46989	8	0.724
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	MK327947	Escherichia phage vB_EcoM_G5211, complete genome	123821-123849	8	0.724
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	NC_041936	Escherichia phage ECD7, complete genome	126064-126092	8	0.724
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	AY343333	Enterobacteria phage RB49, complete genome	123682-123710	8	0.724
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	MK327935	Escherichia phage vB_EcoM_G2494, complete genome	126619-126647	8	0.724
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	MK962753	Shigella phage JK32, complete genome	136063-136091	8	0.724
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	NC_012740	Enterobacteria phage JSE, complete genome	127422-127450	8	0.724
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	MN850574	Escherichia phage kaaroe, complete genome	146936-146964	8	0.724
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	MN850615	Escherichia phage kvi, complete genome	60987-61015	8	0.724
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	MN894885	Escherichia virus Ec_Makalu_001, complete genome	122754-122782	8	0.724
NZ_CP047813_6	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	MN882349	Escherichia virus Ec_Makalu_003, complete genome	123140-123168	8	0.724
NZ_CP047813_13	13.1\|2566499\|34\|NZ_CP047813\|CRISPRCasFinder	2566499-2566532	34	JN882286	Cronobacter phage vB_CsaP_GAP52, complete genome	23034-23067	8	0.765
NZ_CP047813_13	13.1\|2566499\|34\|NZ_CP047813\|CRISPRCasFinder	2566499-2566532	34	CP030544	Staphylococcus aureus strain ER04166.3 plasmid unnamed2, complete sequence	7567-7600	8	0.765
NZ_CP047813_1	1.1\|224868\|33\|NZ_CP047813\|CRISPRCasFinder	224868-224900	33	MF459647	Erwinia phage vB_EamM_Joad, complete genome	84795-84827	9	0.727
NZ_CP047813_1	1.1\|224868\|33\|NZ_CP047813\|CRISPRCasFinder	224868-224900	33	MF459646	Erwinia phage vB_EamM_RisingSun, complete genome	84869-84901	9	0.727

1. spacer 3.1|998536|22|NZ_CP047813|CRISPRCasFinder matches to NC_007021 (Staphylococcus phage Twort, complete genome) position: , mismatch: 2, identity: 0.909

tgataaccctaacaaccctgac	CRISPR spacer
tgataacccaaacaaccctgag	Protospacer
********* ***********

2. spacer 3.1|998536|22|NZ_CP047813|CRISPRCasFinder matches to MT151386 (Staphylococcus virus Twort, complete genome) position: , mismatch: 2, identity: 0.909

tgataaccctaacaaccctgac	CRISPR spacer
tgataacccaaacaaccctgag	Protospacer
********* ***********

3. spacer 8.3|1353374|27|NZ_CP047813|CRT matches to MT416612 (Bacillus phage YungSlug, complete genome) position: , mismatch: 5, identity: 0.815

aaattgcgttcctttaatcttcttgag	CRISPR spacer
gctttgcgttcttttaatgttcttgag	Protospacer
.  ********.****** ********

4. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to NZ_LT984809 (Cupriavidus taiwanensis isolate Cupriavidus taiwanensis STM 8555 plasmid I, complete sequence) position: , mismatch: 6, identity: 0.793

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
aaaatttcaaaatgaaattctgcagtgga	Protospacer
*.******.************.***  .*

5. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to NZ_CP045275 (Bacillus megaterium strain FDU301 plasmid pFDU301C, complete sequence) position: , mismatch: 7, identity: 0.759

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
tagagctcgtaatgaaattctagaggcaa	Protospacer
 ..* .*** ************ ******

6. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to MN655998 (Escherichia phage E26, complete genome) position: , mismatch: 8, identity: 0.724

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
tacttttcgaaataaaattctactggctg	Protospacer
 .  *********.********* *** .

7. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to MH560358 (Escherichia virus KFS-EC, complete genome) position: , mismatch: 8, identity: 0.724

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
tacttttcgaaataaaattctactggctg	Protospacer
 .  *********.********* *** .

8. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to MK573636 (Escherichia phage vB_EcoM_PHB13, partial genome) position: , mismatch: 8, identity: 0.724

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
tacttttcgaaataaaattctactggctg	Protospacer
 .  *********.********* *** .

9. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to MT764208 (Escherichia phage JEP8, complete genome) position: , mismatch: 8, identity: 0.724

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
tacttttcgaaataaaattctactggctg	Protospacer
 .  *********.********* *** .

10. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to MT478991 (Escherichia phage vB_EcoM_011D4, complete genome) position: , mismatch: 8, identity: 0.724

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
tacttttcgaaataaaattctactggctg	Protospacer
 .  *********.********* *** .

11. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to MK327941 (Escherichia phage vB_EcoM_G37-3, complete genome) position: , mismatch: 8, identity: 0.724

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
tacttttcgaaataaaattctactggctg	Protospacer
 .  *********.********* *** .

12. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to NC_009821 (Enterobacteria phage Phi1, complete genome) position: , mismatch: 8, identity: 0.724

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
tacttttcgaaataaaattctactggctg	Protospacer
 .  *********.********* *** .

13. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to MF327006 (Shigella phage Sf20, complete genome) position: , mismatch: 8, identity: 0.724

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
tacttttcgaaataaaattctactggctg	Protospacer
 .  *********.********* *** .

14. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to MK327932 (Escherichia phage vB_EcoM_G2248, complete genome) position: , mismatch: 8, identity: 0.724

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
tacttttcgaaataaaattctactggctg	Protospacer
 .  *********.********* *** .

15. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to NC_025425 (Enterobacteria phage GEC-3S complete genome) position: , mismatch: 8, identity: 0.724

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
tacttttcgaaataaaattctactggctg	Protospacer
 .  *********.********* *** .

16. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to MN709127 (Escherichia virus Ec_Makalu_002, complete genome) position: , mismatch: 8, identity: 0.724

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
tacttttcgaaataaaattctactggctg	Protospacer
 .  *********.********* *** .

17. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to MN732896 (Elizabethkingia phage TCUEAP1, complete genome) position: , mismatch: 8, identity: 0.724

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
tcaatttcgaaatgaaattataccacctg	Protospacer
  ***************** *** . * .

18. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to MK327947 (Escherichia phage vB_EcoM_G5211, complete genome) position: , mismatch: 8, identity: 0.724

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
tacttttcgaaataaaattctactggctg	Protospacer
 .  *********.********* *** .

19. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to NC_041936 (Escherichia phage ECD7, complete genome) position: , mismatch: 8, identity: 0.724

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
tacttttcgaaataaaattctactggctg	Protospacer
 .  *********.********* *** .

20. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to AY343333 (Enterobacteria phage RB49, complete genome) position: , mismatch: 8, identity: 0.724

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
tacttttcgaaataaaattctactggctg	Protospacer
 .  *********.********* *** .

21. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to MK327935 (Escherichia phage vB_EcoM_G2494, complete genome) position: , mismatch: 8, identity: 0.724

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
tacttttcgaaataaaattctactggctg	Protospacer
 .  *********.********* *** .

22. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to MK962753 (Shigella phage JK32, complete genome) position: , mismatch: 8, identity: 0.724

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
tacttttcgaaataaaattctactggctg	Protospacer
 .  *********.********* *** .

23. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to NC_012740 (Enterobacteria phage JSE, complete genome) position: , mismatch: 8, identity: 0.724

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
tacttttcgaaataaaattctactggctg	Protospacer
 .  *********.********* *** .

24. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to MN850574 (Escherichia phage kaaroe, complete genome) position: , mismatch: 8, identity: 0.724

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
tacttttcgaaataaaattctactggctg	Protospacer
 .  *********.********* *** .

25. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to MN850615 (Escherichia phage kvi, complete genome) position: , mismatch: 8, identity: 0.724

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
tacttttcgaaataaaattctactggctg	Protospacer
 .  *********.********* *** .

26. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to MN894885 (Escherichia virus Ec_Makalu_001, complete genome) position: , mismatch: 8, identity: 0.724

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
tacttttcgaaataaaattctactggctg	Protospacer
 .  *********.********* *** .

27. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to MN882349 (Escherichia virus Ec_Makalu_003, complete genome) position: , mismatch: 8, identity: 0.724

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
tacttttcgaaataaaattctactggctg	Protospacer
 .  *********.********* *** .

28. spacer 13.1|2566499|34|NZ_CP047813|CRISPRCasFinder matches to JN882286 (Cronobacter phage vB_CsaP_GAP52, complete genome) position: , mismatch: 8, identity: 0.765

cccagttgcaaacaataaagctaaagatatgcaa	CRISPR spacer
agcatataaaagctataaagctaaagatatgcaa	Protospacer
  **  *. **.* ********************

29. spacer 13.1|2566499|34|NZ_CP047813|CRISPRCasFinder matches to CP030544 (Staphylococcus aureus strain ER04166.3 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.765

cccagttgcaaacaataaagctaaagatatgcaa	CRISPR spacer
tactgtttataacaataaagctaaagttattcaa	Protospacer
. * ***   **************** *** ***

30. spacer 1.1|224868|33|NZ_CP047813|CRISPRCasFinder matches to MF459647 (Erwinia phage vB_EamM_Joad, complete genome) position: , mismatch: 9, identity: 0.727

cattattgaaagctgactattggccagcttcta	CRISPR spacer
gattattggaagctgattattggccggtgttcg	Protospacer
 *******.*******.********.*. *...

31. spacer 1.1|224868|33|NZ_CP047813|CRISPRCasFinder matches to MF459646 (Erwinia phage vB_EamM_RisingSun, complete genome) position: , mismatch: 9, identity: 0.727

cattattgaaagctgactattggccagcttcta	CRISPR spacer
gattattggaagctgattattggccggtgttcg	Protospacer
 *******.*******.********.*. *...

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 54072

Staphylococcus_phage(88.24%)

protease,holin,terminase,tail,capsid,portal,head

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000133309.1\|0_1695_+\|terminase	terminase	D2JLE4	Staphylococcus_phage	0.0e+00	99.8
WP_000644967.1\|1669_1909_+	hypothetical protein	A7TWC1	Staphylococcus_phage	2.0e-34	98.7
WP_160186758.1\|1974_3165_+\|portal	phage portal protein	D2JLE6	Staphylococcus_phage	5.8e-223	99.2
WP_000032523.1\|3157_3742_+\|head,protease	HK97 family phage prohead protease	D2JLE7	Staphylococcus_phage	2.9e-106	99.5
WP_000849958.1\|3829_5077_+\|capsid	phage major capsid protein	Q8SDK8	Staphylococcus_phage	9.2e-211	97.8
WP_001252099.1\|5112_5271_+	hypothetical protein	D2JLE9	Staphylococcus_phage	3.2e-20	100.0
WP_001177489.1\|5279_5612_+\|head,tail	phage head-tail adapter protein	D2JLF0	Staphylococcus_phage	8.2e-58	99.1
WP_000975314.1\|5598_5934_+\|head,tail	head-tail adaptor protein	A7TWC7	Staphylococcus_phage	1.1e-59	100.0
WP_160186678.1\|5933_6311_+	HK97 gp10 family phage protein	D2JLF2	Staphylococcus_phage	4.4e-60	98.4
WP_000611449.1\|6307_6688_+	hypothetical protein	D2JLF3	Staphylococcus_phage	1.3e-67	99.2
WP_000570652.1\|6688_7642_+\|tail	phage tail protein	A7TWD0	Staphylococcus_phage	6.2e-175	100.0
WP_000442601.1\|7706_8153_+	hypothetical protein	D2JLF5	Staphylococcus_phage	5.4e-73	100.0
WP_000571956.1\|8212_8335_+	hypothetical protein	D2JLF6	Staphylococcus_phage	2.6e-14	97.5
WP_160186679.1\|8390_13073_+\|tail	phage tail tape measure protein	Q8SDK4	Staphylococcus_phage	0.0e+00	90.7
WP_001154317.1\|13072_14563_+\|tail	phage tail protein	R9QST9	Staphylococcus_phage	3.1e-298	100.0
WP_000582128.1\|14578_18361_+	hypothetical protein	A0A1V0E5H3	Staphylococcus_phage	0.0e+00	99.8
WP_001000058.1\|18353_18506_+	hypothetical protein	A0A1W6JPL6	Staphylococcus_phage	7.6e-19	100.0
WP_001262620.1\|18551_18839_+	hypothetical protein	C5I682	Staphylococcus_phage	9.9e-44	100.0
WP_000340977.1\|18894_19269_+	hypothetical protein	G4KNR3	Staphylococcus_phage	3.3e-39	100.0
WP_072353918.1\|19411_19588_+\|holin	putative holin-like toxin	D2JLG3	Staphylococcus_phage	5.5e-21	94.8
WP_001791821.1\|19640_19748_-	hypothetical protein	NA	NA	NA	NA
WP_000611512.1\|19799_20054_+\|holin	phage holin	D2JLG4	Staphylococcus_phage	4.1e-41	100.0
WP_000861038.1\|20065_20821_+	CHAP domain-containing protein	D2JLG5	Staphylococcus_phage	3.4e-152	100.0
WP_000920038.1\|21011_21503_+	staphylokinase	A0A1W6JQ12	Staphylococcus_phage	4.7e-86	99.4
WP_001110820.1\|22192_22489_+	peptidoglycan hydrolase	A0A1P8L6B4	Staphylococcus_phage	1.6e-49	95.9
WP_000702263.1\|22999_23350_+	complement inhibitor SCIN-A	A0A1P8L6B0	Staphylococcus_phage	7.5e-54	100.0
WP_001791826.1\|23402_23663_-	hypothetical protein	M9NS66	Staphylococcus_phage	2.3e-23	100.0
WP_000669791.1\|23973_24153_-	hypothetical protein	A0A1W6JQ29	Staphylococcus_phage	1.4e-24	98.3
WP_070248244.1\|25111_26860_+	MAP domain-containing protein	NA	NA	NA	NA
WP_001068542.1\|27439_28726_-	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_000990056.1\|28925_29024_+	hypothetical protein	NA	NA	NA	NA
WP_000681968.1\|29266_29443_+	hypothetical protein	NA	NA	NA	NA
WP_000691584.1\|29701_30082_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_000991302.1\|30078_30975_+	phenol-soluble modulin export ABC transporter ATP-binding protein PmtA	A0A2H4PQG7	Staphylococcus_phage	1.1e-16	30.2
WP_000645726.1\|30975_31656_+	phenol-soluble modulin export ABC transporter permease subunit PmtB	NA	NA	NA	NA
WP_000763048.1\|31652_32525_+	phenol-soluble modulin export ABC transporter ATP-binding protein PmtC	A0A2H4PQG7	Staphylococcus_phage	6.1e-28	35.2
WP_001221651.1\|32524_33265_+	phenol-soluble modulin export ABC transporter permease subunit PmtD	NA	NA	NA	NA
WP_000182842.1\|33330_33894_-	thioredoxin family protein	NA	NA	NA	NA
WP_000966288.1\|34014_34539_+	membrane protein	NA	NA	NA	NA
WP_001033971.1\|34598_35156_+	DUF1700 domain-containing protein	NA	NA	NA	NA
WP_000713059.1\|35152_35995_+	DUF4097 family beta strand repeat protein	NA	NA	NA	NA
WP_043044150.1\|36051_37092_-	linear amide C-N hydrolase	NA	NA	NA	NA
WP_000267034.1\|37542_37716_+	hypothetical protein	NA	NA	NA	NA
WP_000205106.1\|38286_38688_-	YolD-like family protein	U3PG23	Staphylococcus_phage	6.0e-23	42.9
WP_000181322.1\|38957_39986_+	lactonase family protein	NA	NA	NA	NA
WP_043044151.1\|40105_41485_-	aldehyde dehydrogenase	NA	NA	NA	NA
WP_001790680.1\|41536_41710_+	hypothetical protein	NA	NA	NA	NA
WP_001140871.1\|41904_42834_-	manganese-dependent inorganic pyrophosphatase	NA	NA	NA	NA
WP_000149686.1\|42886_43447_-	cysteine hydrolase	G3MA16	Bacillus_virus	2.0e-32	41.2
WP_043044152.1\|43818_44916_+	pectate lyase	U5PWM6	Bacillus_phage	3.7e-46	34.3
WP_000323160.1\|45120_46683_+	SLC13 family permease	NA	NA	NA	NA
WP_001802312.1\|46693_46801_-	hypothetical protein	NA	NA	NA	NA
WP_023914859.1\|46872_47667_-	prephenate dehydratase	NA	NA	NA	NA
WP_043044154.1\|47686_48763_-	nitric oxide synthase oxygenase	NA	NA	NA	NA
WP_000284433.1\|48946_50416_+	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	3.5e-108	45.1
WP_000040866.1\|50408_51230_+	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	2.3e-69	52.7
WP_160186680.1\|51500_52103_+	DUF2179 domain-containing protein	NA	NA	NA	NA
WP_000669862.1\|52083_52257_+	NETI motif-containing protein	NA	NA	NA	NA
WP_000434933.1\|52548_52875_-	staphostatin A	NA	NA	NA	NA
WP_043044155.1\|52905_54072_-\|protease	cysteine protease staphopain A	NA	NA	NA	NA

DBSCAN-SWA_2

118180 : 167717

Staphylococcus_phage(84.21%)

tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001793998.1\|118180_119323_+\|tRNA	tRNA epoxyqueuosine(34) reductase QueG	NA	NA	NA	NA
WP_000181394.1\|119327_119798_+\|tRNA	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	NA	NA	NA	NA
WP_001251224.1\|119956_120556_+	glucosamine-6-phosphate isomerase	NA	NA	NA	NA
WP_000031108.1\|120580_120733_+	hypothetical protein	NA	NA	NA	NA
WP_000901019.1\|121727_122123_+	hypothetical protein	NA	NA	NA	NA
WP_000116236.1\|122318_123704_+	class II fumarate hydratase	NA	NA	NA	NA
WP_000669376.1\|124165_124987_-	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_043044104.1\|125149_126262_+	GAF domain-containing sensor histidine kinase	NA	NA	NA	NA
WP_043044103.1\|126283_126907_+	response regulator transcription factor	NA	NA	NA	NA
WP_000375864.1\|127262_127727_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_043044102.1\|127905_129030_+	DUF445 domain-containing protein	NA	NA	NA	NA
WP_000290301.1\|129098_129443_+	YlbF/YmcA family competence regulator	A0A1X9I5Y8	Streptococcus_phage	7.5e-06	29.7
WP_043044101.1\|130377_131574_+	exonuclease SbcCD subunit D	NA	NA	NA	NA
WP_043044100.1\|131563_134500_+	AAA family ATPase	NA	NA	NA	NA
WP_001244175.1\|134496_135438_+	3'-5' exoribonuclease YhaM	NA	NA	NA	NA
WP_000782121.1\|135558_136521_-	foldase	NA	NA	NA	NA
WP_000477957.1\|136725_137283_-	DUF3267 domain-containing protein	NA	NA	NA	NA
WP_000648118.1\|138017_138383_-	YtxH domain-containing protein	NA	NA	NA	NA
WP_000004981.1\|138524_138947_-	HIT family protein	NA	NA	NA	NA
WP_000216874.1\|139080_139821_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.2e-24	29.8
WP_043044099.1\|139813_141037_+	ABC transporter permease	NA	NA	NA	NA
WP_043044098.1\|141160_141664_-	signal transduction protein TraP	NA	NA	NA	NA
WP_001790154.1\|141826_141937_+	hypothetical protein	NA	NA	NA	NA
WP_000233526.1\|141926_142964_+	uroporphyrinogen decarboxylase	NA	NA	NA	NA
WP_043044096.1\|143021_143945_+	ferrochelatase	NA	NA	NA	NA
WP_000167551.1\|143968_145369_+	protoporphyrinogen oxidase	NA	NA	NA	NA
WP_000132890.1\|145690_146245_+	serine hydrolase family protein	NA	NA	NA	NA
WP_043044094.1\|148701_149490_-	DUF1829 domain-containing protein	A0A2H4PQI0	Staphylococcus_phage	1.9e-145	99.6
WP_043044093.1\|149526_149958_-	hypothetical protein	Q4ZCB9	Staphylococcus_virus	1.6e-61	80.4
WP_000473596.1\|150854_151790_+	beta-channel forming cytolysin	A0A2H4PQI5	Staphylococcus_phage	1.4e-174	100.0
WP_000782463.1\|151791_152775_+	bi-component leukocidin LukED subunit D	A0A2H4PQH7	Staphylococcus_phage	1.8e-185	99.4
WP_000543854.1\|153145_153937_-	DUF1828 domain-containing protein	NA	NA	NA	NA
WP_043044092.1\|153941_154415_-	hypothetical protein	NA	NA	NA	NA
WP_000469595.1\|154670_154889_+	hypothetical protein	A0A2H4PQH0	Staphylococcus_phage	1.4e-26	81.9
WP_043044090.1\|155362_155929_-	DUF4888 domain-containing protein	A0A2H4PQH6	Staphylococcus_phage	1.1e-97	98.4
WP_043044088.1\|156892_157600_+\|protease	serine protease SplA	A0A2H4PQN3	Staphylococcus_phage	2.1e-127	97.4
WP_043044087.1\|157724_158447_+\|protease	serine protease SplB	A0A2H4PQN0	Staphylococcus_phage	2.1e-130	99.2
WP_001038877.1\|158504_159227_+\|protease	serine protease	A0A2H4PQN0	Staphylococcus_phage	2.7e-114	85.0
WP_001039438.1\|159284_160004_+\|protease	serine protease	A0A2H4PQP7	Staphylococcus_phage	1.6e-114	86.6
WP_043044086.1\|160125_160842_+\|protease	serine protease	A0A2H4PQN5	Staphylococcus_phage	9.3e-83	62.2
WP_043044085.1\|160990_161710_+\|protease	serine protease SplD	A0A2H4PQP9	Staphylococcus_phage	1.4e-126	95.8
WP_001038735.1\|161867_162584_+\|protease	serine protease SplE	A0A2H4PQN5	Staphylococcus_phage	1.8e-131	99.2
WP_043044084.1\|162725_163445_+\|protease	serine protease SplF	A0A2H4PQP1	Staphylococcus_phage	3.0e-129	98.3
WP_043044083.1\|163822_165379_+	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	2.8e-286	98.6
WP_070005507.1\|165371_166613_+	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	2.4e-41	33.9
WP_043044081.1\|166862_167717_+	M23 family metallopeptidase	E5G070	Clostridium_phage	4.9e-06	37.9

DBSCAN-SWA_3

173142 : 204023

Staphylococcus_phage(90.0%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_104011150.1\|173142_174226_+\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	1.6e-78	53.6
WP_023914802.1\|174425_174998_-	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	3.2e-25	94.8
WP_000627540.1\|175098_175440_-	DUF3969 family protein	A0A2H4PQN6	Staphylococcus_phage	1.1e-54	94.7
WP_043044073.1\|175480_176107_-	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	1.6e-94	95.2
WP_043044072.1\|176181_177177_-	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	2.6e-67	97.9
WP_072490651.1\|177257_177908_-	calcium-binding protein	A0A2H4PQM8	Staphylococcus_phage	2.0e-55	99.1
WP_072398272.1\|178210_178666_+	DUF4909 domain-containing protein	A0A2H4PQN7	Staphylococcus_phage	3.0e-79	98.6
WP_043044069.1\|178824_180303_+	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	2.1e-278	96.1
WP_160186683.1\|180307_181309_+	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	3.7e-186	97.3
WP_000718107.1\|181305_181563_-	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
WP_000672013.1\|181628_182102_+	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	7.2e-84	98.7
WP_016169057.1\|182106_182853_+	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	2.2e-143	99.2
WP_000109906.1\|183105_184698_-	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	100.0
WP_000933822.1\|185069_186263_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.9e-218	99.7
WP_000366163.1\|186387_187296_+	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	3.4e-138	100.0
WP_000453314.1\|187507_188341_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	5.4e-159	100.0
WP_000623478.1\|188723_189077_-	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	2.6e-22	100.0
WP_001200542.1\|189073_189439_-	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	3.6e-59	100.0
WP_000091445.1\|189694_189997_-	hypothetical protein	NA	NA	NA	NA
WP_001096494.1\|190256_190970_+	transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
WP_001168907.1\|191409_192045_-\|protease	CPBP family intramembrane metalloprotease SdpA	NA	NA	NA	NA
WP_001030469.1\|192340_192784_+	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	2.4e-57	98.6
WP_001153742.1\|192770_193214_-	competence protein ComK	NA	NA	NA	NA
WP_043044066.1\|193326_193797_-	RNA polymerase sigma factor	A0A2H4PQT5	Staphylococcus_phage	2.3e-82	98.7
WP_000384171.1\|193995_194220_+	hypothetical protein	NA	NA	NA	NA
WP_001032833.1\|194495_195350_+	autolysin	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
WP_043044065.1\|195436_196729_-	arsenite efflux transporter membrane subunit ArsB	A0A2H4PQU3	Staphylococcus_phage	1.9e-227	99.5
WP_000221185.1\|196728_197043_-	winged helix-turn-helix transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	4.4e-53	99.0
WP_001261679.1\|197565_199068_+	FAD-dependent oxidoreductase	A0A2H4PQX2	Staphylococcus_phage	2.3e-30	100.0
WP_000384185.1\|199560_200592_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	4.0e-196	98.8
WP_000493892.1\|200598_201231_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.7e-112	99.5
WP_043044063.1\|201241_202423_+	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	1.1e-226	99.5
WP_001008551.1\|202435_202900_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	5.8e-70	99.4
WP_043044062.1\|203021_204023_-	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	2.9e-183	99.1

DBSCAN-SWA_4

207297 : 220027

Staphylococcus_phage(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000764419.1\|207297_207861_-	methyltransferase domain-containing protein	A0A2H4PQV0	Staphylococcus_phage	8.3e-103	99.5
WP_043044059.1\|207857_208811_-	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
WP_001025067.1\|208920_210102_+	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	7.3e-218	99.7
WP_160186684.1\|210393_212808_+\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.3
WP_000836465.1\|212829_213141_+	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	1.6e-52	100.0
WP_006190539.1\|213466_220027_+	LPXTG-anchored repetitive surface protein SasC	A0A2H4PQU6	Staphylococcus_phage	3.5e-309	98.5

DBSCAN-SWA_5

345593 : 354636

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001005768.1\|345593_346598_+	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1
WP_001019178.1\|346599_347625_+\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_001112045.1\|347647_348787_+\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
WP_001160682.1\|348805_349066_+	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
WP_160186685.1\|349340_351620_+	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
WP_043044366.1\|351822_354096_+	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	8.1e-64	29.3
WP_000364542.1\|354117_354636_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5

DBSCAN-SWA_6

422530 : 430860

Caulobacter_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001217257.1\|422530_424348_+	DNA primase	A0A0K1LMQ9	Caulobacter_phage	7.9e-54	36.3
WP_001283055.1\|424571_425678_+	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
WP_000624583.1\|425808_426486_+\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
WP_043044328.1\|426488_427589_+	Nif3-like dinuclear metal center hexameric protein	A0A1S5V250	Saudi_moumouvirus	5.2e-08	29.6
WP_001062177.1\|427702_429049_+	DEAD/DEAH box helicase	A0A1V0SIR5	Klosneuvirus	2.4e-55	34.0
WP_000924214.1\|429058_429949_+	deoxyribonuclease IV	A0A2H4UU70	Bodo_saltans_virus	2.0e-26	33.1
WP_001213908.1\|430074_430860_+	metal ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.0e-19	28.3

DBSCAN-SWA_7

970350 : 978823

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000238664.1\|970350_970917_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	6.1e-29	40.1
WP_000030812.1\|970919_971948_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.3e-61	41.4
WP_000483713.1\|971940_973425_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.2e-45	31.7
WP_000032727.1\|973403_975593_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.0e-140	39.7
WP_000666799.1\|975585_976257_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_000848350.1\|976258_976522_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_000174053.1\|976521_977226_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	7.3e-48	42.1
WP_160186707.1\|977229_978354_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_000861572.1\|978340_978823_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	6.2e-22	44.7

DBSCAN-SWA_8

998752 : 1032059

Enterococcus_phage(16.67%)

transposase,bacteriocin,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_043044609.1\|998752_999934_+\|protease	cysteine protease staphopain B	NA	NA	NA	NA
WP_000284457.1\|999971_1000301_+	staphostatin B	NA	NA	NA	NA
WP_000184947.1\|1000539_1001361_-	1,4-dihydroxy-2-naphthoyl-CoA synthase	NA	NA	NA	NA
WP_000150199.1\|1001353_1002157_-	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase	NA	NA	NA	NA
WP_000526687.1\|1002143_1003817_-	2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase	NA	NA	NA	NA
WP_072399156.1\|1003803_1005015_-	isochorismate synthase	NA	NA	NA	NA
WP_001791731.1\|1005091_1005196_-	hypothetical protein	NA	NA	NA	NA
WP_000070966.1\|1005346_1006285_+	1,4-dihydroxy-2-naphthoate polyprenyltransferase	NA	NA	NA	NA
WP_000620949.1\|1006336_1006888_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_001788574.1\|1006977_1007268_+	TM2 domain-containing protein	A0A060AN66	Enterococcus_phage	7.5e-07	38.0
WP_072353879.1\|1007331_1007463_+	hypothetical protein	NA	NA	NA	NA
WP_001081352.1\|1007508_1008468_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000766009.1\|1008955_1009312_+	DoxX family protein	NA	NA	NA	NA
WP_072399158.1\|1009400_1009589_-	poly(glycerol-phosphate) alpha-glucosyltransferase	NA	NA	NA	NA
WP_001796515.1\|1009678_1009969_+	hypothetical protein	NA	NA	NA	NA
WP_043044616.1\|1010056_1010698_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.7e-20	33.7
WP_000873929.1\|1010694_1011015_-	YxeA family protein	NA	NA	NA	NA
WP_070005428.1\|1011017_1012982_-\|bacteriocin	bacteriocin-associated integral membrane family protein	NA	NA	NA	NA
WP_072399255.1\|1013025_1013298_-\|bacteriocin	lactococcin 972 family bacteriocin	NA	NA	NA	NA
WP_001790623.1\|1013307_1013409_-	hypothetical protein	NA	NA	NA	NA
WP_001033867.1\|1014326_1014929_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000214898.1\|1014943_1015120_-	YkvS family protein	NA	NA	NA	NA
WP_000668823.1\|1015318_1016305_+	lipoate--protein ligase	NA	NA	NA	NA
WP_000876826.1\|1016385_1016604_-	IDEAL domain-containing protein	NA	NA	NA	NA
WP_000287265.1\|1016813_1017383_+	competence protein ComK	NA	NA	NA	NA
WP_043044620.1\|1017869_1019381_-	bifunctional metallophosphatase/5'-nucleotidase	NA	NA	NA	NA
WP_000021872.1\|1019519_1020878_-	TrkH family potassium uptake protein	NA	NA	NA	NA
WP_072399161.1\|1020894_1023219_-\|protease	serine protease	W5SAB9	Pithovirus	2.1e-11	27.4
WP_000928413.1\|1023434_1024238_-	TerC family protein	S5MAL1	Bacillus_phage	1.6e-30	40.5
WP_043044623.1\|1024539_1026102_-	peptide chain release factor 3	A0A1S5SF82	Streptococcus_phage	2.2e-36	28.2
WP_072399163.1\|1026101_1026362_-	hypothetical protein	NA	NA	NA	NA
WP_043044624.1\|1026342_1027827_-	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	NA	NA	NA	NA
WP_043044625.1\|1028259_1029435_+	diglucosyl diacylglycerol synthase	NA	NA	NA	NA
WP_001794241.1\|1029394_1030603_+	MFS transporter	NA	NA	NA	NA
WP_000600387.1\|1030715_1031225_-	hypothetical protein	NA	NA	NA	NA
WP_000251964.1\|1031882_1032059_-\|transposase	IS3 family transposase	A0A0C5AJ30	Paenibacillus_phage	4.5e-07	50.9

DBSCAN-SWA_9

1224837 : 1239712

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000616840.1\|1224837_1225599_-	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	6.5e-18	31.6
WP_043044670.1\|1225595_1226552_-	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
WP_000876318.1\|1226538_1227510_-	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	4.3e-139	78.9
WP_000499195.1\|1227548_1227704_-	hypothetical protein	NA	NA	NA	NA
WP_000562498.1\|1228217_1229189_-	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
WP_000855505.1\|1229306_1231412_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
WP_000692521.1\|1231374_1231773_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
WP_001068497.1\|1232573_1233440_+	DMT family transporter	NA	NA	NA	NA
WP_000930014.1\|1233459_1233960_+	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.9e-52	71.5
WP_000193751.1\|1234299_1235805_+	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
WP_000429014.1\|1236086_1237004_+	lipid kinase	A0A1V0SBJ0	Catovirus	3.7e-07	22.0
WP_000197262.1\|1237772_1238315_-	5'-3'-deoxyribonucleotidase	NA	NA	NA	NA
WP_000663029.1\|1238653_1239712_-	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	2.3e-21	26.4

DBSCAN-SWA_10

1251678 : 1259499

Pandoravirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001217797.1\|1251678_1252830_-	anthranilate synthase component I family protein	S4VNU7	Pandoravirus	2.1e-23	36.1
WP_043044677.1\|1252813_1253407_-	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	2.0e-38	43.5
WP_000446724.1\|1253757_1254426_+	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
WP_000941336.1\|1254427_1254847_+	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	6.3e-07	28.7
WP_001062972.1\|1254850_1255564_+	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
WP_000604990.1\|1255662_1256247_+	hypothetical protein	NA	NA	NA	NA
WP_001093562.1\|1256526_1256967_+	DM13 domain-containing protein	NA	NA	NA	NA
WP_001037807.1\|1257309_1257783_+	DoxX family protein	NA	NA	NA	NA
WP_000149344.1\|1257757_1258444_+	response regulator transcription factor	NA	NA	NA	NA
WP_000244415.1\|1258443_1259499_+	HAMP domain-containing histidine kinase	A0A1V0SGX0	Hokovirus	3.6e-14	29.8

DBSCAN-SWA_11

2711273 : 2733042

Staphylococcus_phage(97.5%)

terminase,integrase

attL 2707996:2708010|attR 2722502:2722516

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2707996:2708010	attL	NA	NA	NA	NA
WP_000791404.1\|2711273_2712326_+	bi-component leukocidin LukGH subunit H	A0A1X9IGW5	Staphylococcus_phage	2.5e-36	34.6
WP_000595401.1\|2712347_2713364_+	bi-component leukocidin LukGH subunit G	A0A2I6PER8	Staphylococcus_phage	2.3e-26	29.3
WP_000857176.1\|2714482_2715520_-\|integrase	site-specific integrase	A7TWL3	Staphylococcus_phage	3.4e-179	100.0
WP_000191459.1\|2715627_2716242_+	hypothetical protein	A7TW88	Staphylococcus_phage	7.9e-107	100.0
WP_001013104.1\|2716238_2716385_-	hypothetical protein	A0A2I6PEK8	Staphylococcus_phage	1.1e-14	89.6
WP_000705243.1\|2716420_2716603_-	hypothetical protein	R9QT81	Staphylococcus_phage	5.3e-27	100.0
WP_000804508.1\|2716647_2717505_-	restriction endonuclease	R9QTP0	Staphylococcus_phage	1.2e-161	100.0
WP_160186753.1\|2717516_2718233_-	helix-turn-helix domain-containing protein	R9QTP6	Staphylococcus_phage	7.8e-130	99.6
WP_000639922.1\|2718396_2718639_+	DUF739 family protein	R9QSU1	Staphylococcus_phage	9.5e-40	100.0
WP_001148565.1\|2718654_2719443_+	phage antirepressor KilAC domain-containing protein	R9QSV3	Staphylococcus_phage	1.2e-144	100.0
WP_001148859.1\|2719458_2719653_+	hypothetical protein	A0A1P8L6G6	Staphylococcus_phage	4.3e-19	100.0
WP_000768245.1\|2719647_2720004_-	DUF2513 domain-containing protein	A0A1P8L6H1	Staphylococcus_phage	6.1e-59	100.0
WP_001148605.1\|2720053_2720806_+	oxidoreductase	M9NTH5	Staphylococcus_phage	1.1e-139	100.0
WP_001148862.1\|2720821_2721019_+	hypothetical protein	O80075	Staphylococcus_phage	3.5e-24	87.7
WP_000762521.1\|2721005_2721386_-	DUF2513 domain-containing protein	Q9T1Z5	Staphylococcus_phage	1.2e-68	100.0
WP_001120201.1\|2721440_2721764_+	DUF771 domain-containing protein	A0A075LYF5	Staphylococcus_phage	3.0e-57	100.0
WP_000048129.1\|2721760_2721922_+	DUF1270 family protein	A0A1P8L6G0	Staphylococcus_phage	1.9e-20	100.0
WP_000165371.1\|2722016_2722319_+	DUF2482 family protein	A0A1P8L6F8	Staphylococcus_phage	7.0e-48	100.0
WP_000291510.1\|2722323_2722584_+	DUF1108 family protein	A0A1P8L6F5	Staphylococcus_phage	5.2e-44	100.0
2722502:2722516	attR	NA	NA	NA	NA
WP_001205732.1\|2722592_2722856_+	hypothetical protein	A0A2I6PDG2	Staphylococcus_phage	7.7e-43	100.0
WP_000700555.1\|2722864_2724808_+	AAA family ATPase	S4V9K6	Staphylococcus_phage	0.0e+00	100.0
WP_000138475.1\|2724809_2725730_+	recombinase	A0A2I6PDH5	Staphylococcus_phage	2.3e-166	100.0
WP_071665632.1\|2725810_2726428_+	MBL fold metallo-hydrolase	A0A0H3U2T4	Staphylococcus_phage	4.1e-87	100.0
WP_000934760.1\|2726428_2726899_+	single-stranded DNA-binding protein	A0EWX3	Staphylococcus_phage	7.4e-81	99.4
WP_043044133.1\|2726928_2727822_+	DnaD domain-containing protein	A0A2I6PDG7	Staphylococcus_phage	2.1e-140	99.0
WP_000338528.1\|2727828_2728047_+	hypothetical protein	A0A1P8L6E4	Staphylococcus_phage	1.4e-37	100.0
WP_000401964.1\|2728055_2728460_+	RusA family crossover junction endodeoxyribonuclease	A0A0E3XBN4	Staphylococcus_phage	1.4e-72	100.0
WP_000101273.1\|2728472_2728841_+	hypothetical protein	I1W656	Staphylococcus_phage	1.2e-49	98.4
WP_000131370.1\|2728844_2729087_+	hypothetical protein	Q4ZDP7	Staphylococcus_virus	2.1e-39	95.0
WP_001065097.1\|2729101_2729356_+	DUF1024 family protein	A0A0H3U469	Staphylococcus_phage	5.0e-39	100.0
WP_001066447.1\|2729505_2730042_+	hypothetical protein	A0A0H3U2Z8	Staphylococcus_phage	7.2e-96	100.0
WP_001282074.1\|2730078_2730324_+	hypothetical protein	A0A2I6PDW7	Staphylococcus_phage	5.0e-36	100.0
WP_000195782.1\|2730320_2730509_+	DUF1381 domain-containing protein	A0A2I6PDV0	Staphylococcus_phage	2.1e-26	100.0
WP_001125015.1\|2730483_2730684_+	hypothetical protein	A0A2I6PF22	Staphylococcus_phage	1.8e-28	100.0
WP_000501855.1\|2730671_2730836_+	transcriptional activator RinB	A0A2I6PDY4	Staphylococcus_phage	5.1e-21	98.1
WP_001813913.1\|2730835_2731036_+	DUF1514 domain-containing protein	R9QT57	Staphylococcus_phage	1.5e-27	98.5
WP_000282752.1\|2731058_2731520_+	hypothetical protein	D2JLE0	Staphylococcus_phage	1.1e-68	100.0
WP_000406193.1\|2731633_2732086_+	nucleoside triphosphate pyrophosphohydrolase family protein	D2JLE1	Staphylococcus_phage	3.9e-79	99.3
WP_016169209.1\|2732101_2732446_+	HNH endonuclease	D2JLE2	Staphylococcus_phage	2.7e-64	98.2
WP_000919027.1\|2732574_2733042_+\|terminase	phage terminase small subunit P27 family	D2JLE3	Staphylococcus_phage	3.3e-81	100.0

Anti-CRISPR protein detection

Acr_ID: NZ_CP047813.1|WP_000499195.1|1227548_1227704_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_CP047813.1|WP_000499195.1|1227548_1227704_-|hypothetical-protein

1227548_1227704_-

51 aa aa

1224837-1239712

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP047813_2	Orphan	2.1\|879128\|26\|NZ_CP047813\|CRISPRCasFinder	879128-879153	26	1227915-1227940	2
NZ_CP047813_6	Orphan	6.1\|1183581\|29\|NZ_CP047813\|CRISPRCasFinder	1183581-1183609	29	1238558-1238586	1
NZ_CP047813_7	Orphan	7.1\|1190792\|25\|NZ_CP047813\|CRISPRCasFinder	1190792-1190816	25	1238559-1238583	0
NZ_CP047813_9	Orphan	9.1\|1722164\|33\|NZ_CP047813\|CRISPRCasFinder	1722164-1722196	33	1227895-1227927	2

1. spacer 2.1|879128|26|NZ_CP047813|CRISPRCasFinder matches to NZ_CP047813 position: 1227915-1227940, mismatch: 2

ccaccagcttctatgttggggccccg	CRISPR spacer
ccgcctgcttctatgttggggccccg	Protospacer
**.** ********************

2. spacer 6.1|1183581|29|NZ_CP047813|CRISPRCasFinder matches to NZ_CP047813 position: 1238558-1238586, mismatch: 1

agaatttcgaaatgaaattctacaggcaa	CRISPR spacer
agaatttcgaaaagaaattctacaggcaa	Protospacer
************ ****************

3. spacer 7.1|1190792|25|NZ_CP047813|CRISPRCasFinder matches to NZ_CP047813 position: 1238559-1238583, mismatch: 0

gaatttcgaaaagaaattctacagg	CRISPR spacer
gaatttcgaaaagaaattctacagg	Protospacer
*************************

4. spacer 9.1|1722164|33|NZ_CP047813|CRISPRCasFinder matches to NZ_CP047813 position: 1227895-1227927, mismatch: 2

cattattgtaagctgactttccgccagcttcta	CRISPR spacer
cattattgttagctgactttccgcctgcttcta	Protospacer
********* *************** *******

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP047813

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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