CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP028223	Lactobacillus plantarum strain SRCM101105 plasmid unnamed1, complete sequence	0 crisprs	csa3	0	4
NZ_CP028222	Lactobacillus plantarum strain SRCM101105 chromosome, complete genome	1 crisprs	DEDDh,cas3,csa3,WYL,cas9,cas1,cas2,csn2,DinG	21	7
NZ_CP028225	Lactobacillus plantarum strain SRCM101105 plasmid unnamed3, complete sequence	0 crisprs	NA	0	0
NZ_CP028224	Lactobacillus plantarum strain SRCM101105 plasmid unnamed2, complete sequence	0 crisprs	NA	0	1

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 14298

Bacillus_virus(16.67%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_120247218.1\|1440_2103_+	metalloregulator ArsR/SmtB family transcription factor	NA	NA	NA	NA
WP_027822611.1\|2238_2523_+	thioredoxin family protein	NA	NA	NA	NA
WP_053339260.1\|2544_3468_+	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	1.8e-78	46.5
WP_053339259.1\|3483_4134_+	DsbA family oxidoreductase	NA	NA	NA	NA
WP_027822614.1\|4288_4603_+	thioredoxin	A0A1X9I9P5	Staphylococcus_phage	2.8e-15	32.7
WP_027822615.1\|4624_5962_+	NAD(P)/FAD-dependent oxidoreductase	A0A2K5B2C5	Erysipelothrix_phage	1.2e-19	23.5
WP_027822616.1\|6467_6830_-	hypothetical protein	NA	NA	NA	NA
WP_027822617.1\|6856_7297_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_010495033.1\|7433_7871_+	OsmC family protein	NA	NA	NA	NA
WP_111443464.1\|7888_8305_+	OsmC family protein	NA	NA	NA	NA
WP_160249570.1\|8687_9722_-\|transposase	IS30 family transposase	A0A2K9V2S9	Faecalibacterium_phage	5.2e-42	34.1
WP_027822898.1\|10075_10399_+	hypothetical protein	NA	NA	NA	NA
WP_027822897.1\|10471_10870_-	hypothetical protein	NA	NA	NA	NA
WP_027822896.1\|10862_11183_-	hypothetical protein	NA	NA	NA	NA
WP_027822895.1\|11175_12477_-	Y-family DNA polymerase	M1Q231	Streptococcus_phage	6.4e-82	40.0
WP_027822894.1\|12590_12902_+	hypothetical protein	NA	NA	NA	NA
WP_016526748.1\|13139_13409_-	hypothetical protein	NA	NA	NA	NA
WP_027822893.1\|13395_14298_-	AAA family ATPase	F0PIG8	Enterococcus_phage	4.1e-27	32.1

DBSCAN-SWA_2

17850 : 27123

Paenibacillus_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_086989537.1\|17850_18625_+\|transposase	IS5-like element ISLpl3 family transposase	A0A0N9SHJ4	Paenibacillus_phage	2.1e-27	53.2
WP_160249572.1\|18661_18898_+	type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family	NA	NA	NA	NA
WP_027822859.1\|19242_19542_-	hypothetical protein	NA	NA	NA	NA
WP_015063546.1\|19534_19813_-	DUF2089 family protein	NA	NA	NA	NA
WP_027822860.1\|20057_20822_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_085844568.1\|21116_22046_-\|transposase	IS30-like element ISLpl1 family transposase	H7BW47	unidentified_phage	2.3e-25	34.4
WP_106904892.1\|22910_23698_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_053339277.1\|24318_27123_+	cation-transporting P-type ATPase	M1IAU8	Acanthocystis_turfacea_Chlorella_virus	2.0e-72	27.6

DBSCAN-SWA_3

31821 : 37776

Staphylococcus_phage(50.0%)

transposase,integrase

attL 22900:22919|attR 50066:50085

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
22900:22919	attL	NA	NA	NA	NA
WP_039098794.1\|31821_32409_-\|integrase	site-specific integrase	D2XR58	Bacillus_phage	4.9e-21	34.3
WP_015474708.1\|33303_33552_-	hypothetical protein	C1KFC0	Lactobacillus_virus	1.3e-36	95.1
WP_027823042.1\|33691_34375_+\|transposase	IS6 family transposase	A0A0N9RU54	Staphylococcus_phage	1.6e-60	53.3
WP_027822875.1\|35131_35803_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_027822874.1\|35807_37055_-	ABC transporter permease	NA	NA	NA	NA
WP_027822873.1\|37032_37776_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.2e-27	33.5
50066:50085	attR	NA	NA	NA	NA

DBSCAN-SWA_4

42302 : 54443

Bacillus_phage(16.67%)

transposase,integrase

attL 41465:41478|attR 47697:47710

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
41465:41478	attL	NA	NA	NA	NA
WP_053339267.1\|42302_42893_+\|integrase	site-specific integrase	D2XR58	Bacillus_phage	7.5e-22	34.3
WP_160249571.1\|43258_43633_+	hypothetical protein	NA	NA	NA	NA
WP_053339269.1\|43652_44546_+\|transposase	IS982 family transposase	NA	NA	NA	NA
WP_053339270.1\|44646_46020_+	sigma-70 family RNA polymerase sigma factor	A0A2I7SAT0	Vibrio_phage	6.2e-27	30.7
WP_053339271.1\|46040_49319_+	ATP-dependent DNA helicase RecQ	A0A1V0SBK0	Catovirus	8.7e-27	27.8
47697:47710	attR	NA	NA	NA	NA
WP_053339272.1\|49757_50099_-	type II toxin-antitoxin system YafQ family toxin	NA	NA	NA	NA
WP_053339273.1\|50558_51734_-\|transposase	IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.1e-27	29.2
WP_003586674.1\|52330_52609_-	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
WP_087613294.1\|52673_53603_-\|transposase	IS30 family transposase	H7BVY4	unidentified_phage	2.8e-23	28.9
WP_013356291.1\|53888_54443_+	recombinase family protein	A0A1J1J8Z4	Escherichia_phage	2.0e-32	44.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP028222

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP028222_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP028222_1

2140831-2143110

TypeII

Consensus_repeat	Method
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CRISPRCasFinder
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CRT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	PILER-CR

34 spacers

csn2,cas2,cas1,cas9,csa3

The CRISPR arrays of NZ_CP028222_1

>merge|NZ_CP028222|1|2140831-2143110|CRISPRCasFinder,CRT,PILER-CR
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACAAAATGGATTTCTGAGCATTACTGTCCGACGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACGACTATACCAATGAGGTCGAAGCATGGTTAGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACCACAAGGCCACCGAGGAAGCCGGCGAGCTAGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACGTTTTTAGCAGATTTAATGAATTCGTCATCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACTAGGTTTACTCATGGTAAATCCTCCTATGTGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACAAAATAAATTTAAGGTTGCGCAACACAATGGTCTTGAATAGTAGTCATATCAAACAGGTTTGGAACAACTCATCATAAATGACGTCTTTTACCGAGGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACTTAGGTTGAGCTGGATCGGGATCAGGATCGGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACTCTGTTGTTTAATTTGTTTTAGATTGTTACGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACACTAAAGCCGGGGTATACAGCCCCGAAGAAGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACAAAATAGTTCGACGAAAAAGCCGAAAGAGAGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACGCGGCCACGACCGCCATGGGTGTCAGCGCCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACTCGGATAACTTAGCGGCGGCGTATCCCTGCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACTACCGGGTGTTAAATCTGAATTAGAAGCGCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACTCATCAACATTTTCATCAACGCGACTAGTTGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACATAGTGACAGCATCTGTTTTCGGACCAATCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACTGTCCATACGAGCAGCGTTGGCACTTATTCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACGTATTATTATCAACGTCCCGCATTGCGTTAGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACAGGATATATGAAATTAGTACATGTACTAGTGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACACGTCTTTCAGCCCAGTAAACTGCTCAAGTGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACTTGAATACCATTCCTTGTTTATACTCCATCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACAGTTCATAATCATATGATCTAAGTGACGGTGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACGGCCGGGTTAATCTTAATGTTTTATGTTCTGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACCAATCAGAAAGAAGATGACGACTATAATGCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACGACTTATACCAGCAGTACCGAAGACGGTTAGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACAACTGGGAGCGGTCAACACCCCAGGCTGTGGTCTTGAATAGTATTCATATCAAACAGGTTTAGAACACGCAAAGCCAGCCCTAGTCATGAGGTCATGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACGTTGCAACTTTATCCTTGTCACTTTCAACAGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACCAATACCATAGTAGTCAATTATTACACGTCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACGCCAAACAACATTGCAGAGAGCTAGTGCTTGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACGTGACGTGCTCCCATGTGACCCGAATTGACGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACCGACTCTAATGGATATTTTCAATCATAGCAGTCTTGAATAGTAGTCATATCAAATAGGTTTAGAACGATGGTGCTGTTGCACGTGATCCCGCGCTTGTCTTGAATAGTAGTCATATCAAGCAGGTTTAGAATAGCATAATGTATTATGTAACATATTATGTTGTCTTGAATAACGGCCACATCAAAAACAGTTTCACA

>NZ_CP028222|1|1|2140831-2143044|CRISPRCasFinder
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AAAATGGATTTCTGAGCATTACTGTCCGAC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GACTATACCAATGAGGTCGAAGCATGGTTA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CACAAGGCCACCGAGGAAGCCGGCGAGCTA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GTTTTTAGCAGATTTAATGAATTCGTCATC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TAGGTTTACTCATGGTAAATCCTCCTATGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AAAATAAATTTAAGGTTGCGCAACACAATG
GTCTTGAATAGTAGTCATATCAAACAGGTTTGGAAC	AACTCATCATAAATGACGTCTTTTACCGAG
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TTAGGTTGAGCTGGATCGGGATCAGGATCG
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TCTGTTGTTTAATTTGTTTTAGATTGTTAC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	ACTAAAGCCGGGGTATACAGCCCCGAAGAA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AAAATAGTTCGACGAAAAAGCCGAAAGAGA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GCGGCCACGACCGCCATGGGTGTCAGCGCC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TCGGATAACTTAGCGGCGGCGTATCCCTGC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TACCGGGTGTTAAATCTGAATTAGAAGCGC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TCATCAACATTTTCATCAACGCGACTAGTT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	ATAGTGACAGCATCTGTTTTCGGACCAATC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TGTCCATACGAGCAGCGTTGGCACTTATTC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GTATTATTATCAACGTCCCGCATTGCGTTA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AGGATATATGAAATTAGTACATGTACTAGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	ACGTCTTTCAGCCCAGTAAACTGCTCAAGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TTGAATACCATTCCTTGTTTATACTCCATC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AGTTCATAATCATATGATCTAAGTGACGGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GGCCGGGTTAATCTTAATGTTTTATGTTCT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CAATCAGAAAGAAGATGACGACTATAATGC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GACTTATACCAGCAGTACCGAAGACGGTTA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AACTGGGAGCGGTCAACACCCCAGGCTGTG
GTCTTGAATAGTATTCATATCAAACAGGTTTAGAAC	ACGCAAAGCCAGCCCTAGTCATGAGGTCAT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GTTGCAACTTTATCCTTGTCACTTTCAACA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CAATACCATAGTAGTCAATTATTACACGTC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GCCAAACAACATTGCAGAGAGCTAGTGCTT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GTGACGTGCTCCCATGTGACCCGAATTGAC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CGACTCTAATGGATATTTTCAATCATAGCA
GTCTTGAATAGTAGTCATATCAAATAGGTTTAGAAC	GATGGTGCTGTTGCACGTGATCCCGCGCTT
GTCTTGAATAGTAGTCATATCAAGCAGGTTTAGAAT

>NZ_CP028222|1|1|2140831-2143110|CRT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AAAATGGATTTCTGAGCATTACTGTCCGAC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GACTATACCAATGAGGTCGAAGCATGGTTA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CACAAGGCCACCGAGGAAGCCGGCGAGCTA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GTTTTTAGCAGATTTAATGAATTCGTCATC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TAGGTTTACTCATGGTAAATCCTCCTATGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AAAATAAATTTAAGGTTGCGCAACACAATG
GTCTTGAATAGTAGTCATATCAAACAGGTTTGGAAC	AACTCATCATAAATGACGTCTTTTACCGAG
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TTAGGTTGAGCTGGATCGGGATCAGGATCG
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TCTGTTGTTTAATTTGTTTTAGATTGTTAC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	ACTAAAGCCGGGGTATACAGCCCCGAAGAA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AAAATAGTTCGACGAAAAAGCCGAAAGAGA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GCGGCCACGACCGCCATGGGTGTCAGCGCC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TCGGATAACTTAGCGGCGGCGTATCCCTGC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TACCGGGTGTTAAATCTGAATTAGAAGCGC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TCATCAACATTTTCATCAACGCGACTAGTT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	ATAGTGACAGCATCTGTTTTCGGACCAATC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TGTCCATACGAGCAGCGTTGGCACTTATTC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GTATTATTATCAACGTCCCGCATTGCGTTA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AGGATATATGAAATTAGTACATGTACTAGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	ACGTCTTTCAGCCCAGTAAACTGCTCAAGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TTGAATACCATTCCTTGTTTATACTCCATC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AGTTCATAATCATATGATCTAAGTGACGGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GGCCGGGTTAATCTTAATGTTTTATGTTCT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CAATCAGAAAGAAGATGACGACTATAATGC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GACTTATACCAGCAGTACCGAAGACGGTTA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AACTGGGAGCGGTCAACACCCCAGGCTGTG
GTCTTGAATAGTATTCATATCAAACAGGTTTAGAAC	ACGCAAAGCCAGCCCTAGTCATGAGGTCAT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GTTGCAACTTTATCCTTGTCACTTTCAACA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CAATACCATAGTAGTCAATTATTACACGTC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GCCAAACAACATTGCAGAGAGCTAGTGCTT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GTGACGTGCTCCCATGTGACCCGAATTGAC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CGACTCTAATGGATATTTTCAATCATAGCA
GTCTTGAATAGTAGTCATATCAAATAGGTTTAGAAC	GATGGTGCTGTTGCACGTGATCCCGCGCTT
GTCTTGAATAGTAGTCATATCAAGCAGGTTTAGAAT	AGCATAATGTATTATGTAACATATTATGTT
GTCTTGAATAACGGCCACATCAAAAACAGTTTCACA

>NZ_CP028222|1|1|2141557-2143044|PILER-CR
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GCGGCCACGACCGCCATGGGTGTCAGCGCC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TCGGATAACTTAGCGGCGGCGTATCCCTGC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TACCGGGTGTTAAATCTGAATTAGAAGCGC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TCATCAACATTTTCATCAACGCGACTAGTT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	ATAGTGACAGCATCTGTTTTCGGACCAATC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TGTCCATACGAGCAGCGTTGGCACTTATTC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GTATTATTATCAACGTCCCGCATTGCGTTA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AGGATATATGAAATTAGTACATGTACTAGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	ACGTCTTTCAGCCCAGTAAACTGCTCAAGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TTGAATACCATTCCTTGTTTATACTCCATC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AGTTCATAATCATATGATCTAAGTGACGGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GGCCGGGTTAATCTTAATGTTTTATGTTCT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CAATCAGAAAGAAGATGACGACTATAATGC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GACTTATACCAGCAGTACCGAAGACGGTTA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AACTGGGAGCGGTCAACACCCCAGGCTGTG
GTCTTGAATAGTATTCATATCAAACAGGTTTAGAAC	ACGCAAAGCCAGCCCTAGTCATGAGGTCAT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GTTGCAACTTTATCCTTGTCACTTTCAACA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CAATACCATAGTAGTCAATTATTACACGTC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GCCAAACAACATTGCAGAGAGCTAGTGCTT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GTGACGTGCTCCCATGTGACCCGAATTGAC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CGACTCTAATGGATATTTTCAATCATAGCA
GTCTTGAATAGTAGTCATATCAAATAGGTTTAGAAC	GATGGTGCTGTTGCACGTGATCCCGCGCTT
GTCTTGAATAGTAGTCATATCAAGCAGGTTTAGAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP028222.1\|WP_063722122.1\|2134673_2138750_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	mkCas0193_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|374653
NZ_CP028222.1\|WP_003641738.1\|2151824_2153018_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340897
NZ_CP028222.1\|WP_060684251.1\|2138943_2139849_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NZ_CP028222.1\|WP_063722121.1\|2133602_2134385_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP028222.1\|WP_063722125.1\|2146196_2146955_+\|nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|350158
NZ_CP028222.1\|WP_045351420.1\|2143173_2145912_-\|cation-transporting-P-type-ATPase	unknown	unknown	gnl\|CDD\|319775
NZ_CP028222.1\|WP_063721935.1\|2127212_2128805_+\|DNA-binding-protein	unknown	unknown	gnl\|CDD\|214906
NZ_CP028222.1\|WP_063722127.1\|2153261_2154110_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381297
NZ_CP028222.1\|WP_003643663.1\|2150137_2151370_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340949
NZ_CP028222.1\|WP_003643664.1\|2151394_2151760_+\|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
NZ_CP028222.1\|WP_063722120.1\|2132870_2133578_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP028222.1\|WP_003646321.1\|2147973_2148447_+\|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_CP028222.1\|WP_003641730.1\|2146997_2147192_-\|PspC-domain-containing-protein	unknown	unknown	gnl\|CDD\|377200
NZ_CP028222.1\|WP_069302347.1\|2130945_2132640_-\|IS1182-family-transposase	unknown	unknown	gnl\|CDD\|376573
NZ_CP028222.1\|WP_063722126.1\|2147257_2147860_-\|NAD(P)H-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|377026
NZ_CP028222.1\|WP_003641733.1\|2148592_2149015_+\|Hsp20/alpha-crystallin-family-protein	unknown	unknown	gnl\|CDD\|107228
NZ_CP028222.1\|WP_003641724.1\|2128920_2129391_-\|NUDIX-hydrolase	unknown	unknown	gnl\|CDD\|240033
NZ_CP028222.1\|WP_063722123.1\|2139826_2140132_+\|CRISPR-associated-endonuclease-Cas2	cas2	mkCas0206_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|226043
NZ_CP028222.1\|WP_063722124.1\|2140128_2140806_+\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd12218_csn2_CAS-II-A	gnl\|CDD\|213411
NZ_CP028222.1\|WP_003641725.1\|2129623_2130988_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|182694

Protein	Function_ID	Function_description	E-value
NZ_CP028222.1\|WP_063722122.1\|2134673_2138750_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|374653	pfam16592, Cas9_REC, REC lobe of CRISPR-associated endonuclease Cas9. The REC lobe of Cas9 - the CRISPR-associated endonuclease Cas9 - includes the REC1 and REC2 domains. REC1 forms an elongated, alpha-helical structure consisting of 25 alpha helices and two beta-sheets, whereas REC2 inserted within REC1 adopts a six-helix bundle structure. The REC lobe and the NUC lobe of Cas9 fold to present a positively charged groove at their interface which accommodates the negatively charged sgRNA:target DNA heteroduplex. CRISPR (clustered regularly interspaced short palindromic repeat)-Cas system occurs naturally in bacteria as a defense against invasion by phages or other mobile genetic elements. Cas9 is targeted to specific genomic locations by sgRNAs or single guide RNAs, in order to complex with invading DNA in order to cleave it and render it inactive.	4.24614e-129
NZ_CP028222.1\|WP_003641738.1\|2151824_2153018_+\|MFS-transporter	gnl\|CDD\|340897	cd17339, MFS_NIMT_CynX_like, 2-nitroimidazole and cyanate transporters and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Escherichia coli 2-nitroimidazole transporter (NIMT) and cyanate transport protein CynX, and similar proteins. NIMT, also called YeaN, confers resistance to 2-nitroimidazole, the antibacterial and antifungal antibiotic, by mediating the active efflux of this compound. CynX is part of an active transport system that transports exogenous cyanate into E. coli cells. The NIMT/CynX-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	7.6578e-118
NZ_CP028222.1\|WP_060684251.1\|2138943_2139849_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	1.76066e-89
NZ_CP028222.1\|WP_063722125.1\|2146196_2146955_+\|nucleoside-phosphorylase	gnl\|CDD\|350158	cd09007, NP-I_spr0068, uncharacterized subfamily of the nucleoside phosphorylase-I family. This subfamily is composed of uncharacterized members including Streptococcus pneumoniae hypothetical protein spr0068. The nucleoside phosphorylase-I (NP-I) family members accept a range of purine nucleosides as well as the pyrimidine nucleoside uridine. The NP-1 family includes phosphorolytic nucleosidases such as purine nucleoside phosphorylase (PNP, EC. 2.4.2.1), uridine phosphorylase (UP, EC 2.4.2.3), and 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP, EC 2.4.2.28), and hydrolytic nucleosidases such as AMP nucleosidase (AMN, EC 3.2.2.4) and 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase (MTAN, EC 3.2.2.16). Members of the NP-I family display different physiologically relevant quaternary structures: hexameric (trimer-of-dimers arrangement of Shewanella oneidensis MR-1 UP); homotrimeric (human PNP and Escherichia coli PNPII or XapA); hexameric (with some evidence for co-existence of a trimeric form) such as E. coli PNPI (DeoD); or homodimeric such as human and Trypanosoma brucei UP. The NP-I family is distinct from nucleoside phosphorylase-II, which belongs to a different structural family.	1.48358e-89
NZ_CP028222.1\|WP_003641730.1\|2146997_2147192_-\|PspC-domain-containing-protein	gnl\|CDD\|377200	pfam04024, PspC, PspC domain. This family includes Phage shock protein C (PspC) that is thought to be a transcriptional regulator. The presumed domain is 60 amino acid residues in length.	2.12668e-17
NZ_CP028222.1\|WP_045351420.1\|2143173_2145912_-\|cation-transporting-P-type-ATPase	gnl\|CDD\|319775	cd02080, P-type_ATPase_cation, P-type cation-transporting ATPase similar to Exiguobacterium aurantiacum Mna, an Na(+)-ATPase, and Synechocystis sp. PCC 6803 PMA1, a putative Ca(2+)-ATPase. This subfamily includes the P-type Na(+)-ATPase of an alkaliphilic bacterium Exiguobacterium aurantiacum Mna and cyanobacterium Synechocystis sp. PCC 6803 PMA1, a cation-transporting ATPase which may translocate calcium. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_CP028222.1\|WP_063721935.1\|2127212_2128805_+\|DNA-binding-protein	gnl\|CDD\|214906	smart00910, HIRAN, The HIRAN protein (HIP116, Rad5p N-terminal) is found in the N-terminal regions of the SWI2/SNF2 proteins typified by HIP116 and Rad5p. HIRAN is found as a standalone protein in several bacteria and prophages, or fused to other catalytic domains, such as a nuclease of the restriction endonuclease fold and TDP1-like DNA phosphoesterases, in the eukaryotes. It has been predicted that this protein functions as a DNA-binding domain that probably recognises features associated with damaged DNA or stalled replication forks.	2.11625e-17
NZ_CP028222.1\|WP_063722127.1\|2153261_2154110_+\|aldo/keto-reductase	gnl\|CDD\|381297	cd19071, AKR_AKR1-5-like, AKR1/2/3/4/5 family of aldo-keto reductase (AKR) and similar proteins. Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. The family includes AKR1A/B/C/D/E/G/I, AKR2A/B/C/D/E, AKR3A/B/C/D/E/G, AKR4A/B/C, AKR5A/B/C/D/E/F/G/H, and similar proteins.	2.6134e-121
NZ_CP028222.1\|WP_003643663.1\|2150137_2151370_+\|MFS-transporter	gnl\|CDD\|340949	cd17391, MFS_MdtG_MDR_like, Multidrug resistance protein MdtG and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli multidrug resistance protein MdtG, Streptococcus pneumoniae multidrug resistance efflux pump PmrA, and similar multidrug resistance (MDR) transporters from bacteria. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtG confers resistance to fosfomycin and deoxycholate. PmrA serves as an efflux pump for various substrates and is associated with fluoroquinolone resistance. MdtG-like MDR transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	7.1962e-140
NZ_CP028222.1\|WP_003643664.1\|2151394_2151760_+\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	7.3086e-14
NZ_CP028222.1\|WP_063722126.1\|2147257_2147860_-\|NAD(P)H-dependent-oxidoreductase	gnl\|CDD\|377026	pfam03358, FMN_red, NADPH-dependent FMN reductase.	2.80954e-31
NZ_CP028222.1\|WP_003641733.1\|2148592_2149015_+\|Hsp20/alpha-crystallin-family-protein	gnl\|CDD\|107228	cd06471, ACD_LpsHSP_like, Group of bacterial proteins containing an alpha crystallin domain (ACD) similar to Lactobacillus plantarum (Lp) small heat shock proteins (sHsp) HSP 18.5, HSP 18.55 and HSP 19.3. sHsps are molecular chaperones that suppress protein aggregation and protect against cell stress, and are generally active as large oligomers consisting of multiple subunits. Transcription of the genes encoding Lp HSP 18.5, 18.55 and 19.3 is regulated by a variety of stresses including heat, cold and ethanol. Early growing L. plantarum cells contain elevated levels of these mRNAs which rapidly fall of as the cells enter stationary phase. Also belonging to this group is Bifidobacterium breve (Bb) HSP20 and Oenococcus oenis (syn. Leuconostoc oenos) (Oo) HSP18. Transcription of the gene encoding BbHSP20 is strongly induced following heat or osmotic shock, and that of the gene encoding OoHSP18 following heat, ethanol or acid shock. OoHSP18 is peripherally associated with the cytoplasmic membrane.	2.47416e-43
NZ_CP028222.1\|WP_003646321.1\|2147973_2148447_+\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	0.000122978
NZ_CP028222.1\|WP_069302347.1\|2130945_2132640_-\|IS1182-family-transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	9.62335e-15
NZ_CP028222.1\|WP_063722121.1\|2133602_2134385_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	2.17929e-25
NZ_CP028222.1\|WP_003641724.1\|2128920_2129391_-\|NUDIX-hydrolase	gnl\|CDD\|240033	cd04677, Nudix_Hydrolase_18, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	8.22877e-58
NZ_CP028222.1\|WP_063722123.1\|2139826_2140132_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	1.86227e-25
NZ_CP028222.1\|WP_063722124.1\|2140128_2140806_+\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213411	cd12218, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	2.3635e-80
NZ_CP028222.1\|WP_003641725.1\|2129623_2130988_+\|amino-acid-permease	gnl\|CDD\|182694	PRK10746, PRK10746, putative transport protein YifK; Provisional.	0

>NZ_CP028222.1|WP_063722124.1|2140128_2140806_+|type-II-A-CRISPR-associated-protein-Csn2
MNITYYPFPPFKIDAGKVNVLDLGNSNMYAEVCQGFRDRIDSVRISNDDLELQTMSSQCNWYGDLMLSVDLNRLFLKKVQTQIIKLMADDRQVAVLDENRKVVSQVMEASFLLDLPLDVDESPSLEQILKFTGIHFPTELMNDPRAILEALVQTHVELGLKQKLVLTNISHYLDQKQWASFEQLVHDLGATVIVIEYSEINRMEKFKNSCYYYVDEDLVDWRDMN
>NZ_CP028222.1|WP_063722123.1|2139826_2140132_+|CRISPR-associated-endonuclease-Cas2
MRLIVMFDVPMDTSEERRAYRHFHKALVREGFLMMQYSTYVRVCVNKKAAEFVEKRIAPLAPKGGKVQTMTVTEKQYQAMHYIQGTPSNDVLNSAERTIVI
>NZ_CP028222.1|WP_060684251.1|2138943_2139849_+|type-II-CRISPR-associated-endonuclease-Cas1
MGWRNVIITQHAKVSYSMNRILVQTSSDKYAVPISDIQLLLVGTTQAVITSAALCALAEAHVKVIFTDHQGEPISETNDYYPTRRTADLVRQQVTWPEARIATLWTKNVGSKILNQIQVIDFVGGDTQTLVDELDKLELNDVTNREAVVANKYFSLLFGDQFYRRDFSPINAALNYGYAVLLSMVNREIVLNGYLTCIGIHHENNENEFNLGSDLMEPFRPIVDQWVSQQRFKDFTPDIKIGLVSLLDLEIGFNGHQTIVSHAITEYVAACLHYLSGETEELKIEVKLPDEVSSDAINSHV
>NZ_CP028222.1|WP_063722122.1|2134673_2138750_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MKEPYGVGLDIGTNSVGWTVVDASGHVRKIKGQTGIGVRLFKEGAAAADRRGFRTTRRRLKRVKWRLRLLREFFDQPISKVDINFFARRKYSDISPRDPNYNGLEKTLFNDRSDQDFYHDYPTIYHLREALMTQHRKFDVREIYLAIHHIVKYRGNFLRNDAATAYRSGTLDLQQHFETLNHLFSQADLELNLNLTTDVALLDSIKQTLVRTDISRSDRQKLIMPLLAVLTGATTAEKKRQKAVVTEFAKALVGNKTKIDVLTLTDIDATEAKDWAFSLEENQDKLPGIEDRFSEVGQQIIDEVIRLYASVNLAQLIPEGKRFSQSMVEKYKRHGEDLKLLKAYIRSQSDAKRGRAIRATYDQYIDGVKSKQVTQEAFQKALGKFVDADVDLNSWAAQIKQAIDSEQFMPKLRTKQNGAIPYQVQQNELDQIINNQKEYYPWLGEENPVIKRRGKFPYKLDELVGFRVPYYVGPLITKEMQAATANAGFAWMVRKADGPITPWNFDDKVDRVASATAFIQRMQTTDTYLIGEEVLPARSLIYQRFMVLNELNNIRVDDGQLTPRQKQRLYNQVFKKHKRVTAKNIQDNLVAAGEFPTAPRITGLADPKVFNSSLSTYHDLKQVLPEAMSDVRKQADIEKIILWSTIFEDSTIFKQKLTEISWLTAAQLKQLGQLRYRGWGQLSRKLLTGLKDDNNRSIMDGLWETNANFMQLRSQPAIENQIKSANQANLTTADLQDTINELYTSPQNKKAIREVMVVLADIKDAMHGQTPNWIFVEAARGGGVAGRRTQSRSKQIVAAYQGTAQVIVSDQVQRELKEKIKNKANFNTRLVLYFLQNGRDLYTGDAINIDRLSEYDIDHILPQSLVKDDSLDNRVLTNARINREKNDTFASEKFGKKMGAKWKEMHRMGLMTKRKLDHLLMRPDEISKYATGFINRQLVETRQVIKLVEELINAEYPSTAIVSVKANLTHQFRQTFDFPKIREVNDYHHAFDAALTAFIGTYLLKRYPKLERFFVYGKFAKQPVNLTRFNVIRKLAKTDTPITDIDTGEVLWDKLTDIKYFETLYDYKRLLVTREVSENYGAMFDQTLLKASDNGKRLIRKKQSFDTAIYGGYTGKTLAYMAIVKVSTKKDVQYQVVGVPTTMVTQIEQLEQQGMTNKQAVTKVIEPLIAANNKKMLTYEVLLPKVRFEQVVRDRIKGQTHRFALGTDTYYHNIQELYLPLTLQRAFLGKQNESEVQLNQNLLTVFDATLAQVNRYFPLYEMNKFKKILNSARDQIELLEAKNQFVKNKLVLGKQGILTNMFIGLHANASFGDLKSLGVKTSFGQLQVPGGIKLTGDAEIIYQSPTGLFERKIALKDL
>NZ_CP028222.1|WP_063722121.1|2133602_2134385_+|alpha/beta-hydrolase
MHFITSDHVQLDYTDEGQGQPIVILTGFGGAKDIWRAQIPVLIQAGYRVINLDGRCQGLSEHTAKGLRMSRRAVDAHELIEKLQLEQPILLGNSMGAATWFAYVSLYGDTGIKALIDVDQTPQMINTPHWQYGFKQVQWQDIPDYFRMPLGHSTFKHIDDATYARVKAVEAQAPFDAKLMFPLLVNHAVQDWRDVIRQLTVPFLIIAGAKSPFFNPDFAAVTAQMALRGQSVVIPEAGHIVMAEQSAAFNKALLEFLATC
>NZ_CP028222.1|WP_063722120.1|2132870_2133578_+|hypothetical-protein
MVKQGHYAKVSKQKRLRQLKQRRQAQEKRAIMPEMVSEFLQVRYHLTQAAKQRPAMRQMMQRFMAQWLAAGQAELSDNGQTTWSVVALTKQTLQTFNRQLPWQGYALVDQEMARWTAFLNKEVPAVPLSERITLTEALSPATWQACLSEQLAVNALLALTGDSRQLSQITTEQVRQLQTSIQTATGIDWEKVAQLLDSTVIAQNTLSEAEPDDKTRQWLEKLQKLTPQDFNNHVE
>NZ_CP028222.1|WP_069302347.1|2130945_2132640_-|IS1182-family-transposase
MQDYYNMNQTTLSIALDYQPEEHHPARYINQLVESLKLKYDYQFGRPREYNLGAMLKLVLLAYCYGIFSSRKIEQFARENKPAGWLIADQIPSYRTICRFRISDELATLTTDSLSQLTQYLRQNGMIDDVSFIDGTKILADANKYSFVWKKNTIRFDKMNREKLVDLLGELHEAKIVGEIPAGSELTPELLDIMISKVEDHLVVLNETVEATKQVSPNPAKQQRRTVKSQKRKLNKRRDKMREHQAQQAIYGQRNSYSKTDHDATFMRVKEDPMQNGQLKPAYNVQIATSNQFITGYRLFQNPTDTRTLQPFIEHLKANNVLGHTIVADAGYGSESNYRYLEDEFGQHTVLIPYGTMLKENSRKWQSDDRKVMNWDYHEKDDYFINPQNVRFNFNAYRQRTDKYGFTRDFKEYIAEKYDENHQLIAAALTPKGYLKRISVNENWEYFKSKQRELLSAPETGQIYAQRKIDVEPVFGKMKASLHFNRFSVRGFDKVTKEAGIVILALNIMKLVTVGTNFKNQRRKQMGRETKIRFLVPFAYTEASYVTASLDYNVSSLLPAYLRK
>NZ_CP028222.1|WP_003641725.1|2129623_2130988_+|amino-acid-permease
MQRKLSTGQMQMIALGGTIGVGLFMGSSSTIKWTGPSVLIAYIVSGAFLYLIMRALGEMLYVDPNTGSFAKFASEYIHPVFGYLTAWSNIFQFVVVGMSEMIALGGYCRYWWPNLPDWIPGLIAIVFLCAANLISVKMFGTLETWFSLIKVVTIILMIIAGLGLIIFGIGNGGHPIGISNLWTHGGFFTGGVKGFVFALAIVLASYQGIELIGVTAGEAENPQSTIVKAIRSTVARILIFYVGAIFVIVSIYPWDKLSQIGSPFVQTFAKIGITAAASIINFVVITASLSGTNSGIYSASRMTYTLAESHQLPRKMTLLNRHGVPFYSVIAIATGILIGVVLNVVLPMFFKDASEIFVMVYSSSVLPGMVPWFVILVSQIAFRKQNAAKMANHPFKMPLSPYSNYLTLAFLALTLVFMFINPETRYSILVGVVFLVIMTLIYFRKYAGNKEETL
>NZ_CP028222.1|WP_003641724.1|2128920_2129391_-|NUDIX-hydrolase
MANYIKEIRALVGHKPIILNTAAGILVNDQQQVLLNLRTDTHNWSLPGGYLEYGETYATACVREYKEDSGIDVEVVDRIGIFDKGETAYPNGDVAQTISALFLVKPIGGHVLTQATDETLKLDYFDFDNLPPLLNQQNADMIHAAQEYLQTHSATK
>NZ_CP028222.1|WP_063721935.1|2127212_2128805_+|DNA-binding-protein
MERIEAGMSVMTLKKQTYRVIAVINQGQELLVRAHEPETADIEIIPVTTVVQVTEQNSTDDAAVALDTVTVVGERYVDDIVATLTTLRVGMAVLLQRESGNQYDDNAISVWTLQHAKLGYIARYQNQPYATLMDQGQRLYGIVTVLDQQKQHLELMLWRTTAVPSPIEALQIRQRLAKPRTNLGAVPTHSLQTPLGTIVMMCNGHPIKYQQVPLSPWLTPADELHVTKRYLLTPDWSQVPPDSLITCQVTAKADVVQRWQNEHISAAVLTNASSFYVVGISAQTKTGLNDNLVDDVAQPAVIYRVGQVSAHMQAGFMVSWAPFGDPRVQPALKLALHFSSQPLVLYHPVTPSRTNATFTQQELAALLVSALPNYQGGQRLEPSVTAITVEKLRQTLGDQTYHALANYQRHVQLVAGSTEGVNETLLQALIHAVTYHELTTMHYYQPTVGMVDQVIYPIQLFSTTTKDEDDAQLVGCLALYNYETFEIQQVPLTAIARIAIIADPEHPQTTPETESPDWLRIFLHGWNDDF
>NZ_CP028222.1|WP_045351420.1|2143173_2145912_-|cation-transporting-P-type-ATPase
MIKDDNQSLTSNEEQNDTQNPPDADNLWQLDESALAAKYATDPENGLSTAEAAERLQHNGRNELETKRTSRFVQFIKQFNNSIIYILAAAAVLTFFMHHYSDSIVIGLVIIANAIIGYVQERQAGNALERIREMLISKNFVIRDGKKLEIDARELVVGDLVNLEAGDAVPADMRLISADNFNVQESVLTGETNPVEKQEEPMTETTPALADRKNMVYASTAVTSGSAVGIVTATAEDTEIGHIQQSVSDVKQTTTPLMRNLNSLGFGLSIAIVVAAVLLFLLGMVMDTYSLPTLLIAVITMVVGSMPEGLPASTSVVLAMGTRQMTKKNVIVKSLPAVETLGAVDIVNTDKTGTLTKNEMTVTKVVTPEHTFDVTGVGYDDNGGVNFDGHLKLNGNKVDWHQDNAMEWLVKIAGQTTDAELHFENNRWELTGEPTDGALTTLYRKMTGHDPEVEEVDSLPFDSAFRFSARLADLDGQRLLMVKGSPATVLRLTDQANQTAYWDDAMDDLTADGLRVVALAYQEVDDDVTTIDAQAIGGLHLAGLVGIIDPPREEAATAIAELRQAGVQVKMITGDHPDTAMAIANKLNLAANVKAITGPEIDAMDDQQLQAHIDDYNVFARATPNNKLRIVRAQQANNHVVSMTGDGVNDAPALKQADIGVAMGIKGTEVAKESADMVLADDDFADIVAAVREGRHVFDNIRKTIRFLLPTSFAEGLVVIISILMGHELPLYPTQLLWINMVSALTIQFAFIFEPPEAGIMARGPRNVKSGLLSKLDYFEIGYVSFLISGLGIFAYNYLTALGLPNVVGSTMSLNIIIFGKIFYLFNLRNDHPVISKYFFQNKMAFYIIGILILLQLGIIYLPFMQSVFHTTSINFWYGWGIPIICGIVVLIVTEVGKFIRFRWMGKDGVID
>NZ_CP028222.1|WP_063722125.1|2146196_2146955_+|nucleoside-phosphorylase
MTDKLTLLQYDPNPTAMVGPDVDGRFTVPAKLLYIFSGDDYFQQFVTRYHGHRLGQFNTITKVSWVYQIGYRGQKLAVAQAPLGSPAATMYLEMLIDFGARTVIAVGSCGALTALPEEQLLIPTVALRDEGTSFHYLAAADWVPLDPRVIQVLGTTLTKACLPWQMVKTWTTDAFFRETVSKVKAARQQGCQVVEMECSALAACSAFRQVSFGQLLYTADTLAQLEHYDPRHWGAGGVLVAIELATESLAAY
>NZ_CP028222.1|WP_003641730.1|2146997_2147192_-|PspC-domain-containing-protein
MKIDIHRSATDRVIAGVIGGIAEHFNWNTNVTRLLFVVLAITPMFPGIIAYLILWLLMKDPIKD
>NZ_CP028222.1|WP_063722126.1|2147257_2147860_-|NAD(P)H-dependent-oxidoreductase
MFKIAIILGSTRSQANGRALFNHLKLIIDQLPTHSTIHYQFLDLANYQLPLFDEPEPPMANPHRELPANQQQWLTDMASADGYIILTPEYNHAMPAGLKNAFDFLAFEGARKPAKIISYSDNMRGGQFGAAALVPVLQRLGMVVLPKPTPIGNVPQTLQSNGHFIDNAPLSKRYDRALHQALTEITYYTTVLTTTPFPTD
>NZ_CP028222.1|WP_003646321.1|2147973_2148447_+|winged-helix-turn-helix-transcriptional-regulator
MTTPLVSQLMTELNQFLTQDSVDDQEKRWAMQQTTDPQLQAALKQLSTTDIKIIAYLGRRGASRAKSLPAPTELSQATISRGLTKLSRLKLATKYRDLTNNKEILVRLTTLGEAVADLHTQLDAAIAAKAQAIADDYSDAELRRFVSLMRRIREIKI
>NZ_CP028222.1|WP_003641733.1|2148592_2149015_+|Hsp20/alpha-crystallin-family-protein
MANTLMNRNDFGMLDPFERMARSFWAPLENMDQVLKTDINETDDQYQVKVDVPGIDKQDVKLDYRDNVLSIKVQKDSFVDHEDQDQNIVMNERHTGTLQRQYMLPNVAADKITASQADGVLTITLPKTQPSANDGQIEIQ
>NZ_CP028222.1|WP_003643663.1|2150137_2151370_+|MFS-transporter
MDDAERERGPWHRNLIVLWFCTFVAGMAFSEIMPFLSLFVSQLGDFTKAQITFYSGLAFAADYAISAISAPLWGIIADKKGRKIMLLRASLGMAVAMGLMGFVTNVWQLVALRALQGVFAGFISNAQALVASQTPRKYSGRALSTLITGAVSGQLFGPVIGGLLAQLFSIRNTFFITAGLLMVAFLLSLFFVQEHFKPVAHHREPGDSRNPLAAFQNPRLIIVMLCSTAIVQFGNASIAPIISLYVRELMHYRGPITVVAGIIAALPGISNIFSAPRLGRYGDQHGSGKVLLFGYIFAVIMYFPQGIVTSVVALGILRFAIGISDGALYPEIQTVLTKNTPVHLTSTIFSYNQSFQAIGNMFGALLGGLVAGWFNYNAVFIMTALLLLINLGLILWLVPDIWKNGKRAVS
>NZ_CP028222.1|WP_003643664.1|2151394_2151760_+|winged-helix-turn-helix-transcriptional-regulator
MASCLFCYLSLNMMLIQCIVSFMNIEISKQDQADQQRVAIFKALADANRLRIIRVLYQAQREMTCSEVGAQLNISKSTVSYHFKTLRLVGLTNTRRKAQTKYLSLQLATFDRFLPGFLATL
>NZ_CP028222.1|WP_003641738.1|2151824_2153018_+|MFS-transporter
MTTTHQHSRYLTLGMMLAATNMRLPITMMPGLISSLKRTLGLPSSMAGLLTTIPLLTFAIMSPLIAHWGRRFGNELTIYVMLIFLAVGSYLRVIPTIAALFIGTLLVGIGADGGNVLIPAIIKDNFPTKIPVATSQYTLSMLLVGSLGTGLSGVLAAHWSLPLTMAVLSVIGLINLVVWLPNLKYNHRAPTVAMTASDGQSTATHGSVWRRPLAWVVTAFFGLQALVYYSLLTWLPTVFVAHGFSLIVAGNLVTVMQLSGLPMSYLVPATSGHRRGVWAMIMVVGVGFIAGIGGILLSGTNFWVAALSCVLLGLGSGAAFSLAVVFFTQKTTNGFETADLSGMAQSAGYLLAAVGPVLFGWLGGQLGWGPVLWLAIILSALLALSGSIIFQHATIYE
>NZ_CP028222.1|WP_063722127.1|2153261_2154110_+|aldo/keto-reductase
MTVLTTMYQLANGVNIPKVAFGTWQIPGGEATYQAVRAALAAGYRHIDTALAYQNEASVGQAIRDSGIPREQIFVTTKLPAETKSYQGALNDFDRSLKNLGLDYVDLYLVHAPWPWGQVGRVYDEANLDVWQAMEAIYQSGRAKAIGVSNFAVRDLKNILNQATIPPMVNQIQYYLGFTEPKITKFSEEHAMLVEAYSPLATGGVLDNPQVQAYADKYGVSVAQLALRFVLQNGVLPLPKAVNPAHIEANTQLDFAISVADMQALNDLPDAAGSYMHNLTQG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP028222_1	1.20\|2142121\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2142121-2142150	30	NC_004305	Lactobacillus phage phig1e, complete genome	33581-33610	0	1.0
NZ_CP028222_1	1.20\|2142121\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2142121-2142150	30	X98106	Lactobacillus bacteriophage phig1e complete genomic DNA	33581-33610	0	1.0
NZ_CP028222_1	1.16\|2141857\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2141857-2141886	30	NZ_CP025993	Lactobacillus plantarum subsp. plantarum strain LB1-2 plasmid pLB1-2B, complete sequence	35085-35114	1	0.967
NZ_CP028222_1	1.21\|2142187\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2142187-2142216	30	JX486087	Lactobacillus phage ATCC 8014-B1, complete genome	30242-30271	3	0.9
NZ_CP028222_1	1.12\|2141593\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2141593-2141622	30	JX486087	Lactobacillus phage ATCC 8014-B1, complete genome	8954-8983	4	0.867
NZ_CP028222_1	1.21\|2142187\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2142187-2142216	30	JN051154	Pediococcus phage clP1, complete genome	15025-15054	4	0.867
NZ_CP028222_1	1.3\|2140999\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140999-2141028	30	NC_020062	Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence	457051-457080	5	0.833
NZ_CP028222_1	1.20\|2142121\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2142121-2142150	30	AY682195	Lactobacillus plantarum bacteriophage LP65, complete genome	7535-7564	5	0.833
NZ_CP028222_1	1.20\|2142121\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2142121-2142150	30	NC_006565	Lactobacillus phage LP65, complete genome	7535-7564	5	0.833
NZ_CP028222_1	1.20\|2142121\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2142121-2142150	30	NZ_CP014913	Lactobacillus paracollinoides strain TMW 1.1979 plasmid pL11979-1, complete sequence	43852-43881	5	0.833
NZ_CP028222_1	1.20\|2142121\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2142121-2142150	30	NZ_CP014925	Lactobacillus paracollinoides strain TMW 1.1995 plasmid pL11995-1, complete sequence	1277-1306	5	0.833
NZ_CP028222_1	1.20\|2142121\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2142121-2142150	30	KU052488	Lactobacillus phage SA-C12, complete genome	48107-48136	5	0.833
NZ_CP028222_1	1.3\|2140999\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140999-2141028	30	MN585972	Arthrobacter phage Edmundo, complete genome	37248-37277	6	0.8
NZ_CP028222_1	1.3\|2140999\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140999-2141028	30	NZ_CP012477	Arthrobacter sp. ERGS1:01 isolate water plasmid unnamed2, complete sequence	226094-226123	6	0.8
NZ_CP028222_1	1.3\|2140999\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140999-2141028	30	MK894437	Microbacterium phage MonChoix, complete genome	5804-5833	6	0.8
NZ_CP028222_1	1.3\|2140999\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140999-2141028	30	NZ_CP026091	Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence	1460937-1460966	6	0.8
NZ_CP028222_1	1.3\|2140999\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140999-2141028	30	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	1258097-1258126	6	0.8
NZ_CP028222_1	1.3\|2140999\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140999-2141028	30	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	1461084-1461113	6	0.8
NZ_CP028222_1	1.3\|2140999\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140999-2141028	30	NZ_CP021767	Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence	1211727-1211756	6	0.8
NZ_CP028222_1	1.3\|2140999\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140999-2141028	30	NZ_CP021765	Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence	1250630-1250659	6	0.8
NZ_CP028222_1	1.8\|2141329\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2141329-2141358	30	NZ_AP018205	Leptolyngbya boryana NIES-2135 plasmid plasmid2 DNA, complete genome	71233-71262	6	0.8
NZ_CP028222_1	1.8\|2141329\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2141329-2141358	30	NZ_AP014640	Leptolyngbya boryana IAM M-101 plasmid pLBX	434240-434269	6	0.8
NZ_CP028222_1	1.24\|2142385\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2142385-2142414	30	NZ_CP044283	Rhodococcus erythropolis strain X5 plasmid pRhX5, complete sequence	239270-239299	6	0.8
NZ_CP028222_1	1.24\|2142385\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2142385-2142414	30	NZ_CP017303	Rhodococcus sp. YL-1 plasmid pYLL1 sequence	104800-104829	6	0.8
NZ_CP028222_1	1.24\|2142385\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2142385-2142414	30	NZ_CP042915	Rhodococcus qingshengii strain RL1 plasmid unnamed2	184929-184958	6	0.8
NZ_CP028222_1	1.34\|2143045\|30\|NZ_CP028222\|CRT	2143045-2143074	30	MK250021	Prevotella phage Lak-B2, complete genome	300362-300391	6	0.8
NZ_CP028222_1	1.34\|2143045\|30\|NZ_CP028222\|CRT	2143045-2143074	30	MK250024	Prevotella phage Lak-B5, complete genome	294384-294413	6	0.8
NZ_CP028222_1	1.34\|2143045\|30\|NZ_CP028222\|CRT	2143045-2143074	30	MK250028	Prevotella phage Lak-B9, complete genome	299274-299303	6	0.8
NZ_CP028222_1	1.34\|2143045\|30\|NZ_CP028222\|CRT	2143045-2143074	30	MK250023	Prevotella phage Lak-B4, complete genome	300906-300935	6	0.8
NZ_CP028222_1	1.34\|2143045\|30\|NZ_CP028222\|CRT	2143045-2143074	30	MK250025	Prevotella phage Lak-B6, complete genome	297576-297605	6	0.8
NZ_CP028222_1	1.34\|2143045\|30\|NZ_CP028222\|CRT	2143045-2143074	30	MK250022	Prevotella phage Lak-B3, complete genome	297591-297620	6	0.8
NZ_CP028222_1	1.34\|2143045\|30\|NZ_CP028222\|CRT	2143045-2143074	30	MK250027	Prevotella phage Lak-B8, complete genome	299598-299627	6	0.8
NZ_CP028222_1	1.34\|2143045\|30\|NZ_CP028222\|CRT	2143045-2143074	30	MK250026	Prevotella phage Lak-B7, complete genome	298656-298685	6	0.8
NZ_CP028222_1	1.34\|2143045\|30\|NZ_CP028222\|CRT	2143045-2143074	30	MK250020	Prevotella phage Lak-B1, complete genome	299257-299286	6	0.8
NZ_CP028222_1	1.1\|2140867\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140867-2140896	30	KX961630	Bacillus phage QCM8, complete genome	50060-50089	7	0.767
NZ_CP028222_1	1.3\|2140999\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140999-2141028	30	NZ_CP012748	Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence	1676275-1676304	7	0.767
NZ_CP028222_1	1.3\|2140999\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140999-2141028	30	AX955019	Sequence 1 from Patent WO03093461	24256-24285	7	0.767
NZ_CP028222_1	1.3\|2140999\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140999-2141028	30	NZ_CP034999	Rhizobium acidisoli strain FH23 plasmid pRapFH23a, complete sequence	566335-566364	7	0.767
NZ_CP028222_1	1.3\|2140999\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140999-2141028	30	NC_008270	Rhodococcus jostii RHA1 plasmid pRHL2, complete sequence	265258-265287	7	0.767
NZ_CP028222_1	1.3\|2140999\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140999-2141028	30	NZ_KU140623	Sinorhizobium sp. M14 plasmid pSinB, complete sequence	185121-185150	7	0.767
NZ_CP028222_1	1.3\|2140999\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140999-2141028	30	MF614628	Sinorhizobium phage phi3LM21, complete genome	5122-5151	7	0.767
NZ_CP028222_1	1.5\|2141131\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2141131-2141160	30	KX507046	Vibrio phage S4-7, complete genome	56857-56886	7	0.767
NZ_CP028222_1	1.8\|2141329\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2141329-2141358	30	MH669013	Gordonia phage Skysand, complete genome	27210-27239	7	0.767
NZ_CP028222_1	1.8\|2141329\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2141329-2141358	30	MK977699	Gordonia Phage Lollipop1437, complete genome	27754-27783	7	0.767
NZ_CP028222_1	1.14\|2141725\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2141725-2141754	30	MK560763	Virgibacillus phage Mimir87, complete genome	8629-8658	7	0.767
NZ_CP028222_1	1.19\|2142055\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2142055-2142084	30	LR215721	Staphylococcus phage Stab22 genome assembly, chromosome: I	2364-2393	7	0.767
NZ_CP028222_1	1.19\|2142055\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2142055-2142084	30	LR215721	Staphylococcus phage Stab22 genome assembly, chromosome: I	144638-144667	7	0.767
NZ_CP028222_1	1.22\|2142253\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2142253-2142282	30	NC_014389	Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence	275012-275041	7	0.767
NZ_CP028222_1	1.26\|2142517\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2142517-2142546	30	NC_006362	Nocardia farcinica IFM 10152 plasmid pNF1, complete sequence	173494-173523	7	0.767
NZ_CP028222_1	1.26\|2142517\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2142517-2142546	30	NZ_LN868941	Nocardia farcinica strain NCTC11134 plasmid 4, complete sequence	83638-83667	7	0.767
NZ_CP028222_1	1.26\|2142517\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2142517-2142546	30	NZ_CP031419	Nocardia farcinica strain W6977 plasmid unnamed1, complete sequence	25519-25548	7	0.767
NZ_CP028222_1	1.29\|2142715\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2142715-2142744	30	NZ_CP024791	Nostoc flagelliforme CCNUN1 plasmid pNFSY06, complete sequence	197362-197391	7	0.767
NZ_CP028222_1	1.29\|2142715\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2142715-2142744	30	NZ_CP015007	Aminobacter aminovorans strain KCTC 2477 plasmid pAA02, complete sequence	122733-122762	7	0.767
NZ_CP028222_1	1.33\|2142979\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2142979-2143008	30	NZ_CP015089	Pelagibaca abyssi strain JLT2014 plasmid pPABY5, complete sequence	37190-37219	7	0.767
NZ_CP028222_1	1.1\|2140867\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140867-2140896	30	MN013089	Bacillus phage vB_BspM_MarvelLand, complete genome	137765-137794	8	0.733
NZ_CP028222_1	1.1\|2140867\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140867-2140896	30	MH688040	Salmonella phage Mooltan, complete genome	70183-70212	8	0.733
NZ_CP028222_1	1.1\|2140867\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140867-2140896	30	NC_025446	Escherichia phage ECML-4, complete genome	125647-125676	8	0.733
NZ_CP028222_1	1.1\|2140867\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140867-2140896	30	MN342150	Escherichia phage vB_EcoM_3HA11, complete genome	38164-38193	8	0.733
NZ_CP028222_1	1.1\|2140867\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140867-2140896	30	NC_023856	Salmonella phage vB_SalM_SJ2, complete genome	146281-146310	8	0.733
NZ_CP028222_1	1.1\|2140867\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140867-2140896	30	MH427377	Escherichia phage vB_EcoM Sa157lw, complete genome	38644-38673	8	0.733
NZ_CP028222_1	1.1\|2140867\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140867-2140896	30	FQ312032	Salmonella phage Vi01 complete sequence	90217-90246	8	0.733
NZ_CP028222_1	1.1\|2140867\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140867-2140896	30	NC_015296	Salmonella phage Vi01, complete genome	90217-90246	8	0.733
NZ_CP028222_1	1.1\|2140867\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140867-2140896	30	MN066127	Salmonella phage Matapan, complete genome	70171-70200	8	0.733
NZ_CP028222_1	1.2\|2140933\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140933-2140962	30	NC_004349	Shewanella oneidensis MR-1 megaplasmid, complete sequence	34495-34524	8	0.733
NZ_CP028222_1	1.3\|2140999\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140999-2141028	30	NZ_CP032695	Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525c, complete sequence	44384-44413	8	0.733
NZ_CP028222_1	1.3\|2140999\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140999-2141028	30	JN106173	Uncultured bacterium plasmid pAKD31, complete sequence	48838-48867	8	0.733
NZ_CP028222_1	1.3\|2140999\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140999-2141028	30	JN106174	Uncultured bacterium plasmid pAKD33, complete sequence	52672-52701	8	0.733
NZ_CP028222_1	1.3\|2140999\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140999-2141028	30	JN106165	Uncultured bacterium plasmid pAKD14, complete sequence	43322-43351	8	0.733
NZ_CP028222_1	1.3\|2140999\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140999-2141028	30	JN106166	Uncultured bacterium plasmid pAKD15, complete sequence	61248-61277	8	0.733
NZ_CP028222_1	1.3\|2140999\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140999-2141028	30	JN106168	Uncultured bacterium plasmid pAKD17, complete sequence	46452-46481	8	0.733
NZ_CP028222_1	1.3\|2140999\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140999-2141028	30	NZ_CP038640	Cupriavidus oxalaticus strain X32 plasmid unnamed5, complete sequence	32603-32632	8	0.733
NZ_CP028222_1	1.3\|2140999\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140999-2141028	30	NZ_CP026526	Sinorhizobium meliloti strain AK21 plasmid pSymA, complete sequence	613932-613961	8	0.733
NZ_CP028222_1	1.3\|2140999\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140999-2141028	30	NC_019320	Variovorax sp. DB1 plasmid pDB1, complete sequence	31677-31706	8	0.733
NZ_CP028222_1	1.3\|2140999\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140999-2141028	30	KY676784	Streptomyces phage ToastyFinz, complete genome	4751-4780	8	0.733
NZ_CP028222_1	1.3\|2140999\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140999-2141028	30	KY092482	Streptomyces phage Mojorita, complete genome	4976-5005	8	0.733
NZ_CP028222_1	1.3\|2140999\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140999-2141028	30	KY092480	Streptomyces phage Picard, complete genome	4976-5005	8	0.733
NZ_CP028222_1	1.3\|2140999\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140999-2141028	30	NZ_LR134463	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 21, complete sequence	98986-99015	8	0.733
NZ_CP028222_1	1.8\|2141329\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2141329-2141358	30	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	708167-708196	8	0.733
NZ_CP028222_1	1.9\|2141395\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2141395-2141424	30	MH617654	Caudovirales sp. isolate ctbf53, complete genome	22891-22920	8	0.733
NZ_CP028222_1	1.12\|2141593\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2141593-2141622	30	KM879463	Arthrobacter phage vB_ArtM-ArV1, complete genome	15860-15889	8	0.733
NZ_CP028222_1	1.15\|2141791\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2141791-2141820	30	NZ_CP013110	Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence	984312-984341	8	0.733
NZ_CP028222_1	1.15\|2141791\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2141791-2141820	30	MK496767	Capybara microvirus Cap3_SP_332, complete genome	4672-4701	8	0.733
NZ_CP028222_1	1.20\|2142121\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2142121-2142150	30	MT104467	Pseudomonas phage MR4, complete genome	6493-6522	8	0.733
NZ_CP028222_1	1.20\|2142121\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2142121-2142150	30	NC_047802	Pectobacterium phage PP99, complete genome	9391-9420	8	0.733
NZ_CP028222_1	1.20\|2142121\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2142121-2142150	30	KJ749827	Escherichia phage ECBP5, complete genome	7250-7279	8	0.733
NZ_CP028222_1	1.24\|2142385\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2142385-2142414	30	MH616711	Inoviridae sp. isolate ctbe45, complete genome	1436-1465	8	0.733
NZ_CP028222_1	1.26\|2142517\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2142517-2142546	30	NC_015729	Roseobacter litoralis Och 149 plasmid pRLO149_63, complete sequence	59709-59738	8	0.733
NZ_CP028222_1	1.26\|2142517\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2142517-2142546	30	NZ_CP027408	Roseobacter denitrificans strain FDAARGOS_309 plasmid unnamed2, complete sequence	61691-61720	8	0.733
NZ_CP028222_1	1.26\|2142517\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2142517-2142546	30	NZ_CP026745	Nocardia cyriacigeorgica strain MDA3349 isolate MDA3349 ancestor plasmid p_unnamed, complete sequence	90557-90586	8	0.733
NZ_CP028222_1	1.26\|2142517\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2142517-2142546	30	NC_008387	Roseobacter denitrificans OCh 114 plasmid pTB2, complete sequence	30719-30748	8	0.733
NZ_CP028222_1	1.34\|2143045\|30\|NZ_CP028222\|CRT	2143045-2143074	30	NC_018516	Bacillus thuringiensis HD-789 plasmid pBTHD789-1, complete sequence	118534-118563	8	0.733
NZ_CP028222_1	1.34\|2143045\|30\|NZ_CP028222\|CRT	2143045-2143074	30	NZ_CP053970	Bacillus thuringiensis strain FDAARGOS_796 plasmid unnamed2, complete sequence	312406-312435	8	0.733
NZ_CP028222_1	1.34\|2143045\|30\|NZ_CP028222\|CRT	2143045-2143074	30	NZ_CP053979	Bacillus thuringiensis strain FDAARGOS_795 plasmid unnamed3, complete sequence	220127-220156	8	0.733
NZ_CP028222_1	1.34\|2143045\|30\|NZ_CP028222\|CRT	2143045-2143074	30	NZ_CP013277	Bacillus thuringiensis serovar israelensis strain AM65-52 plasmid pAM65-52-2-350K, complete sequence	88848-88877	8	0.733
NZ_CP028222_1	1.34\|2143045\|30\|NZ_CP028222\|CRT	2143045-2143074	30	NZ_CP039723	Bacillus thuringiensis strain BT-59 plasmid p2, complete sequence	205849-205878	8	0.733
NZ_CP028222_1	1.34\|2143045\|30\|NZ_CP028222\|CRT	2143045-2143074	30	NZ_CP009348	Bacillus thuringiensis HD1002 plasmid 2, complete sequence	88848-88877	8	0.733
NZ_CP028222_1	1.34\|2143045\|30\|NZ_CP028222\|CRT	2143045-2143074	30	NZ_CP009334	Bacillus thuringiensis strain HD1011 plasmid 2, complete sequence	52730-52759	8	0.733
NZ_CP028222_1	1.34\|2143045\|30\|NZ_CP028222\|CRT	2143045-2143074	30	NZ_CP045024	Bacillus thuringiensis strain JW-1 plasmid p2, complete sequence	88356-88385	8	0.733
NZ_CP028222_1	1.3\|2140999\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140999-2141028	30	NZ_CP010801	Ralstonia mannitolilytica strain SN82F48 plasmid pRMAN01, complete sequence	183710-183739	9	0.7
NZ_CP028222_1	1.3\|2140999\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2140999-2141028	30	NC_008269	Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence	909914-909943	9	0.7
NZ_CP028222_1	1.7\|2141263\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2141263-2141292	30	MN693509	Marine virus AFVG_25M367, complete genome	54175-54204	9	0.7
NZ_CP028222_1	1.7\|2141263\|30\|NZ_CP028222\|CRISPRCasFinder,CRT	2141263-2141292	30	NZ_CP012101	Bacillus thuringiensis strain HS18-1 plasmid pHS18-2, complete sequence	20801-20830	9	0.7
NZ_CP028222_1	1.14\|2141725\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2141725-2141754	30	NZ_CP029457	Bacillus cereus strain FORC087 plasmid pFORC087.3, complete sequence	66140-66169	9	0.7
NZ_CP028222_1	1.20\|2142121\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2142121-2142150	30	NZ_CP032091	Pseudoalteromonas donghaensis strain HJ51 plasmid unnamed1, complete sequence	270177-270206	9	0.7
NZ_CP028222_1	1.25\|2142451\|30\|NZ_CP028222\|CRISPRCasFinder,CRT,PILER-CR	2142451-2142480	30	MN582058	Caudovirales sp. ctOwN3, complete genome	16148-16177	9	0.7

1. spacer 1.20|2142121|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to NC_004305 (Lactobacillus phage phig1e, complete genome) position: , mismatch: 0, identity: 1.0

acgtctttcagcccagtaaactgctcaagt	CRISPR spacer
acgtctttcagcccagtaaactgctcaagt	Protospacer
******************************

2. spacer 1.20|2142121|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to X98106 (Lactobacillus bacteriophage phig1e complete genomic DNA) position: , mismatch: 0, identity: 1.0

acgtctttcagcccagtaaactgctcaagt	CRISPR spacer
acgtctttcagcccagtaaactgctcaagt	Protospacer
******************************

3. spacer 1.16|2141857|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP025993 (Lactobacillus plantarum subsp. plantarum strain LB1-2 plasmid pLB1-2B, complete sequence) position: , mismatch: 1, identity: 0.967

atagtgacagcatctgttttcggaccaatc	CRISPR spacer
atagtgacagcatctgtttttggaccaatc	Protospacer
********************.*********

4. spacer 1.21|2142187|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to JX486087 (Lactobacillus phage ATCC 8014-B1, complete genome) position: , mismatch: 3, identity: 0.9

ttgaataccattccttgtttatactccatc	CRISPR spacer
gtgaataccataccttgtttataatccatc	Protospacer
 ********** *********** ******

5. spacer 1.12|2141593|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to JX486087 (Lactobacillus phage ATCC 8014-B1, complete genome) position: , mismatch: 4, identity: 0.867

gcggccacgaccgccatgggtgtcagcgcc	CRISPR spacer
gcggccacgaccgctatgggtgtcagttca	Protospacer
**************.***********. *

6. spacer 1.21|2142187|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to JN051154 (Pediococcus phage clP1, complete genome) position: , mismatch: 4, identity: 0.867

ttgaataccattccttgtttatactccatc	CRISPR spacer
gtaaataccataccttgtttataatccatc	Protospacer
 *.******** *********** ******

7. spacer 1.3|2140999|30|NZ_CP028222|CRISPRCasFinder,CRT matches to NC_020062 (Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence) position: , mismatch: 5, identity: 0.833

cacaaggccaccgaggaagccggcgagcta	CRISPR spacer
gacacggccaccgaagaagccggcgagcag	Protospacer
 *** *********.************* .

8. spacer 1.20|2142121|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to AY682195 (Lactobacillus plantarum bacteriophage LP65, complete genome) position: , mismatch: 5, identity: 0.833

acgtctttcagcccagtaaactgctcaagt	CRISPR spacer
ttgtctttcagcccagtaaactgttcaacg	Protospacer
 .*********************.****

9. spacer 1.20|2142121|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to NC_006565 (Lactobacillus phage LP65, complete genome) position: , mismatch: 5, identity: 0.833

acgtctttcagcccagtaaactgctcaagt	CRISPR spacer
ttgtctttcagcccagtaaactgttcaacg	Protospacer
 .*********************.****

10. spacer 1.20|2142121|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014913 (Lactobacillus paracollinoides strain TMW 1.1979 plasmid pL11979-1, complete sequence) position: , mismatch: 5, identity: 0.833

acgtctttcagcccagtaaactgctcaagt	CRISPR spacer
acgtctttcaggccggtaaactgctccaaa	Protospacer
*********** **.*********** *.

11. spacer 1.20|2142121|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014925 (Lactobacillus paracollinoides strain TMW 1.1995 plasmid pL11995-1, complete sequence) position: , mismatch: 5, identity: 0.833

acgtctttcagcccagtaaactgctcaagt	CRISPR spacer
acgtctttcaggccggtaaactgctccaaa	Protospacer
*********** **.*********** *.

12. spacer 1.20|2142121|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to KU052488 (Lactobacillus phage SA-C12, complete genome) position: , mismatch: 5, identity: 0.833

acgtctttcagcccagtaaactgctcaagt	CRISPR spacer
aagtctttcagtccagtaaactgttcaaca	Protospacer
* *********.***********.****

13. spacer 1.3|2140999|30|NZ_CP028222|CRISPRCasFinder,CRT matches to MN585972 (Arthrobacter phage Edmundo, complete genome) position: , mismatch: 6, identity: 0.8

cacaaggccaccgaggaagccggcgagcta	CRISPR spacer
cgcaaggccaccgaggaagccgtcgataag	Protospacer
*.******************** ***   .

14. spacer 1.3|2140999|30|NZ_CP028222|CRISPRCasFinder,CRT matches to NZ_CP012477 (Arthrobacter sp. ERGS1:01 isolate water plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.8

cacaaggccaccgaggaagccggcgagcta	CRISPR spacer
caccaggccacccaggaagccggcgcccat	Protospacer
*** ******** ************  *

15. spacer 1.3|2140999|30|NZ_CP028222|CRISPRCasFinder,CRT matches to MK894437 (Microbacterium phage MonChoix, complete genome) position: , mismatch: 6, identity: 0.8

cacaaggccaccgaggaagccggcgagcta	CRISPR spacer
gtcaaggccacggaggaagccgtcgaggtc	Protospacer
  ********* ********** **** *

16. spacer 1.3|2140999|30|NZ_CP028222|CRISPRCasFinder,CRT matches to NZ_CP026091 (Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

cacaaggccaccgaggaagccggcgagcta-	CRISPR spacer
ggcaaggccaccgaggcacccggcg-cctat	Protospacer
 .************** * ******  ***

17. spacer 1.3|2140999|30|NZ_CP028222|CRISPRCasFinder,CRT matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 6, identity: 0.8

cacaaggccaccgaggaagccggcgagcta-	CRISPR spacer
ggcaaggccaccgaggcacccggcg-cctat	Protospacer
 .************** * ******  ***

18. spacer 1.3|2140999|30|NZ_CP028222|CRISPRCasFinder,CRT matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

cacaaggccaccgaggaagccggcgagcta-	CRISPR spacer
ggcaaggccaccgaggcacccggcg-cctat	Protospacer
 .************** * ******  ***

19. spacer 1.3|2140999|30|NZ_CP028222|CRISPRCasFinder,CRT matches to NZ_CP021767 (Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

cacaaggccaccgaggaagccggcgagcta-	CRISPR spacer
ggcaaggccaccgaggcacccggcg-cctat	Protospacer
 .************** * ******  ***

20. spacer 1.3|2140999|30|NZ_CP028222|CRISPRCasFinder,CRT matches to NZ_CP021765 (Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

cacaaggccaccgaggaagccggcgagcta-	CRISPR spacer
ggcaaggccaccgaggcacccggcg-cctat	Protospacer
 .************** * ******  ***

21. spacer 1.8|2141329|30|NZ_CP028222|CRISPRCasFinder,CRT matches to NZ_AP018205 (Leptolyngbya boryana NIES-2135 plasmid plasmid2 DNA, complete genome) position: , mismatch: 6, identity: 0.8

ttaggttgagctggatcgggatcaggatcg	CRISPR spacer
tccgtttgggctgaatcgggatcaggatgg	Protospacer
*. * ***.****.************** *

22. spacer 1.8|2141329|30|NZ_CP028222|CRISPRCasFinder,CRT matches to NZ_AP014640 (Leptolyngbya boryana IAM M-101 plasmid pLBX) position: , mismatch: 6, identity: 0.8

ttaggttgagctggatcgggatcaggatcg	CRISPR spacer
tccgtttgggctgaatcgggatcaggatgg	Protospacer
*. * ***.****.************** *

23. spacer 1.24|2142385|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP044283 (Rhodococcus erythropolis strain X5 plasmid pRhX5, complete sequence) position: , mismatch: 6, identity: 0.8

caatcagaaagaagatgacgactataatgc	CRISPR spacer
cgatcagaaagaagaagacgaccatcaacc	Protospacer
*.************* ******.** *  *

24. spacer 1.24|2142385|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP017303 (Rhodococcus sp. YL-1 plasmid pYLL1 sequence) position: , mismatch: 6, identity: 0.8

caatcagaaagaagatgacgactataatgc	CRISPR spacer
cgatcagaaagaagaagacgaccatcaacc	Protospacer
*.************* ******.** *  *

25. spacer 1.24|2142385|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP042915 (Rhodococcus qingshengii strain RL1 plasmid unnamed2) position: , mismatch: 6, identity: 0.8

caatcagaaagaagatgacgactataatgc	CRISPR spacer
cgatcagaaagaagaagacgaccatcaacc	Protospacer
*.************* ******.** *  *

26. spacer 1.34|2143045|30|NZ_CP028222|CRT matches to MK250021 (Prevotella phage Lak-B2, complete genome) position: , mismatch: 6, identity: 0.8

-agcataatgtattatgtaacatattatgtt	CRISPR spacer
ctacat-atgtattatgtaacatatattgta	Protospacer
  .*** ******************  ***

27. spacer 1.34|2143045|30|NZ_CP028222|CRT matches to MK250024 (Prevotella phage Lak-B5, complete genome) position: , mismatch: 6, identity: 0.8

-agcataatgtattatgtaacatattatgtt	CRISPR spacer
ctacat-atgtattatgtaacatatattgta	Protospacer
  .*** ******************  ***

28. spacer 1.34|2143045|30|NZ_CP028222|CRT matches to MK250028 (Prevotella phage Lak-B9, complete genome) position: , mismatch: 6, identity: 0.8

-agcataatgtattatgtaacatattatgtt	CRISPR spacer
ctacat-atgtattatgtaacatatattgta	Protospacer
  .*** ******************  ***

29. spacer 1.34|2143045|30|NZ_CP028222|CRT matches to MK250023 (Prevotella phage Lak-B4, complete genome) position: , mismatch: 6, identity: 0.8

-agcataatgtattatgtaacatattatgtt	CRISPR spacer
ctacat-atgtattatgtaacatatattgta	Protospacer
  .*** ******************  ***

30. spacer 1.34|2143045|30|NZ_CP028222|CRT matches to MK250025 (Prevotella phage Lak-B6, complete genome) position: , mismatch: 6, identity: 0.8

-agcataatgtattatgtaacatattatgtt	CRISPR spacer
ctacat-atgtattatgtaacatatattgta	Protospacer
  .*** ******************  ***

31. spacer 1.34|2143045|30|NZ_CP028222|CRT matches to MK250022 (Prevotella phage Lak-B3, complete genome) position: , mismatch: 6, identity: 0.8

-agcataatgtattatgtaacatattatgtt	CRISPR spacer
ctacat-atgtattatgtaacatatattgta	Protospacer
  .*** ******************  ***

32. spacer 1.34|2143045|30|NZ_CP028222|CRT matches to MK250027 (Prevotella phage Lak-B8, complete genome) position: , mismatch: 6, identity: 0.8

-agcataatgtattatgtaacatattatgtt	CRISPR spacer
ctacat-atgtattatgtaacatatattgta	Protospacer
  .*** ******************  ***

33. spacer 1.34|2143045|30|NZ_CP028222|CRT matches to MK250026 (Prevotella phage Lak-B7, complete genome) position: , mismatch: 6, identity: 0.8

-agcataatgtattatgtaacatattatgtt	CRISPR spacer
ctacat-atgtattatgtaacatatattgta	Protospacer
  .*** ******************  ***

34. spacer 1.34|2143045|30|NZ_CP028222|CRT matches to MK250020 (Prevotella phage Lak-B1, complete genome) position: , mismatch: 6, identity: 0.8

-agcataatgtattatgtaacatattatgtt	CRISPR spacer
ctacat-atgtattatgtaacatatattgta	Protospacer
  .*** ******************  ***

35. spacer 1.1|2140867|30|NZ_CP028222|CRISPRCasFinder,CRT matches to KX961630 (Bacillus phage QCM8, complete genome) position: , mismatch: 7, identity: 0.767

aaaatggatttctgagcattactgtccgac	CRISPR spacer
taaatggatttctgagcattactacggaaa	Protospacer
 **********************..  .*

36. spacer 1.3|2140999|30|NZ_CP028222|CRISPRCasFinder,CRT matches to NZ_CP012748 (Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cacaaggccaccgaggaagccggcgagcta	CRISPR spacer
tacacggccaccgaggcagccggcgcgtcg	Protospacer
.*** *********** ******** *...

37. spacer 1.3|2140999|30|NZ_CP028222|CRISPRCasFinder,CRT matches to AX955019 (Sequence 1 from Patent WO03093461) position: , mismatch: 7, identity: 0.767

cacaaggccaccgaggaagccggcgagcta	CRISPR spacer
gacgccaccaccgaggaagccgccgagctc	Protospacer
 **.  .*************** ******

38. spacer 1.3|2140999|30|NZ_CP028222|CRISPRCasFinder,CRT matches to NZ_CP034999 (Rhizobium acidisoli strain FH23 plasmid pRapFH23a, complete sequence) position: , mismatch: 7, identity: 0.767

cacaag---gccaccgaggaagccggcgagcta	CRISPR spacer
---atgcttgccaccgaggaaaccggcaagctc	Protospacer
   * *   ************.*****.****

39. spacer 1.3|2140999|30|NZ_CP028222|CRISPRCasFinder,CRT matches to NC_008270 (Rhodococcus jostii RHA1 plasmid pRHL2, complete sequence) position: , mismatch: 7, identity: 0.767

cacaaggccaccgaggaagccggcgagcta	CRISPR spacer
gaacaggccaccgagatagccggcgagtga	Protospacer
 *  ***********. **********. *

40. spacer 1.3|2140999|30|NZ_CP028222|CRISPRCasFinder,CRT matches to NZ_KU140623 (Sinorhizobium sp. M14 plasmid pSinB, complete sequence) position: , mismatch: 7, identity: 0.767

cacaaggccaccgaggaagccggcgagcta	CRISPR spacer
atcaacgccaccgaggaagccgccgcggtt	Protospacer
  *** **************** ** * *

41. spacer 1.3|2140999|30|NZ_CP028222|CRISPRCasFinder,CRT matches to MF614628 (Sinorhizobium phage phi3LM21, complete genome) position: , mismatch: 7, identity: 0.767

cacaaggccaccgaggaagccggcgagcta	CRISPR spacer
gacaaggccgccgaggaaaccggcctgccg	Protospacer
 ********.********.*****  **..

42. spacer 1.5|2141131|30|NZ_CP028222|CRISPRCasFinder,CRT matches to KX507046 (Vibrio phage S4-7, complete genome) position: , mismatch: 7, identity: 0.767

taggtttactcatggtaaatcctcctatgt	CRISPR spacer
caggtttccacatggtaaatcctctagtgg	Protospacer
.****** * **************. .**

43. spacer 1.8|2141329|30|NZ_CP028222|CRISPRCasFinder,CRT matches to MH669013 (Gordonia phage Skysand, complete genome) position: , mismatch: 7, identity: 0.767

ttaggttgagctggatcgggatcaggatcg	CRISPR spacer
cgagcaggcgcaggatcgggatcaggatcg	Protospacer
. **   * ** ******************

44. spacer 1.8|2141329|30|NZ_CP028222|CRISPRCasFinder,CRT matches to MK977699 (Gordonia Phage Lollipop1437, complete genome) position: , mismatch: 7, identity: 0.767

ttaggttgagctggatcgggatcaggatcg	CRISPR spacer
cgagcaggcgcaggatcgggatcaggatcg	Protospacer
. **   * ** ******************

45. spacer 1.14|2141725|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to MK560763 (Virgibacillus phage Mimir87, complete genome) position: , mismatch: 7, identity: 0.767

taccgggtgttaaatctgaattagaagcgc	CRISPR spacer
tgaaagttgttaaatctgaatttgaagcga	Protospacer
*.  .* *************** ******

46. spacer 1.19|2142055|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to LR215721 (Staphylococcus phage Stab22 genome assembly, chromosome: I) position: , mismatch: 7, identity: 0.767

aggatatatgaaattagtacatgtactagt	CRISPR spacer
attttatatgaaattagtatatgaactcat	Protospacer
*   ***************.*** *** .*

47. spacer 1.19|2142055|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to LR215721 (Staphylococcus phage Stab22 genome assembly, chromosome: I) position: , mismatch: 7, identity: 0.767

aggatatatgaaattagtacatgtactagt	CRISPR spacer
attttatatgaaattagtatatgaactcat	Protospacer
*   ***************.*** *** .*

48. spacer 1.22|2142253|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to NC_014389 (Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence) position: , mismatch: 7, identity: 0.767

agttcataatcatatgatctaagtgacggt	CRISPR spacer
ggtatcgaatcatatgatgtaagagacggt	Protospacer
.** .  *********** **** ******

49. spacer 1.26|2142517|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to NC_006362 (Nocardia farcinica IFM 10152 plasmid pNF1, complete sequence) position: , mismatch: 7, identity: 0.767

aactgggagcggtcaacaccccaggctgtg	CRISPR spacer
gcacgggagcggtcgacaccccgggctgtt	Protospacer
.  .**********.*******.******

50. spacer 1.26|2142517|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LN868941 (Nocardia farcinica strain NCTC11134 plasmid 4, complete sequence) position: , mismatch: 7, identity: 0.767

aactgggagcggtcaacaccccaggctgtg	CRISPR spacer
gcacgggagcggtcgacaccccgggctgtt	Protospacer
.  .**********.*******.******

51. spacer 1.26|2142517|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP031419 (Nocardia farcinica strain W6977 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

aactgggagcggtcaacaccccaggctgtg	CRISPR spacer
gcacgggagcggtcgacaccccgggctgtt	Protospacer
.  .**********.*******.******

52. spacer 1.29|2142715|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024791 (Nostoc flagelliforme CCNUN1 plasmid pNFSY06, complete sequence) position: , mismatch: 7, identity: 0.767

caataccatagtagtcaattattacacgtc	CRISPR spacer
ccataccatcgtattcaattattactttcc	Protospacer
* ******* *** *********** . .*

53. spacer 1.29|2142715|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP015007 (Aminobacter aminovorans strain KCTC 2477 plasmid pAA02, complete sequence) position: , mismatch: 7, identity: 0.767

caataccatagtagtcaattattacacgtc	CRISPR spacer
aaataccatagtcgtcaattatcatatttt	Protospacer
 *********** *********.*.*. *.

54. spacer 1.33|2142979|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP015089 (Pelagibaca abyssi strain JLT2014 plasmid pPABY5, complete sequence) position: , mismatch: 7, identity: 0.767

gatggtgctgttgcacgtgatcccgcgctt	CRISPR spacer
ctccgagctgttccaggtgatcccgcgctt	Protospacer
  . * ****** ** **************

55. spacer 1.1|2140867|30|NZ_CP028222|CRISPRCasFinder,CRT matches to MN013089 (Bacillus phage vB_BspM_MarvelLand, complete genome) position: , mismatch: 8, identity: 0.733

aaaatggatttctgagcattactgtccgac	CRISPR spacer
taaatggatttccgagcattactacggaaa	Protospacer
 ***********.**********..  .*

56. spacer 1.1|2140867|30|NZ_CP028222|CRISPRCasFinder,CRT matches to MH688040 (Salmonella phage Mooltan, complete genome) position: , mismatch: 8, identity: 0.733

aaaatggatttctgagcattactgtccgac	CRISPR spacer
aaaattgatttctgagtattactacatcag	Protospacer
***** **********.******.. . *

57. spacer 1.1|2140867|30|NZ_CP028222|CRISPRCasFinder,CRT matches to NC_025446 (Escherichia phage ECML-4, complete genome) position: , mismatch: 8, identity: 0.733

aaaatggatttctgagcattactgtccgac	CRISPR spacer
aaaattgatttctgagtattactacatcag	Protospacer
***** **********.******.. . *

58. spacer 1.1|2140867|30|NZ_CP028222|CRISPRCasFinder,CRT matches to MN342150 (Escherichia phage vB_EcoM_3HA11, complete genome) position: , mismatch: 8, identity: 0.733

aaaatggatttctgagcattactgtccgac	CRISPR spacer
aaaattgatttctgagtattactacatcag	Protospacer
***** **********.******.. . *

59. spacer 1.1|2140867|30|NZ_CP028222|CRISPRCasFinder,CRT matches to NC_023856 (Salmonella phage vB_SalM_SJ2, complete genome) position: , mismatch: 8, identity: 0.733

aaaatggatttctgagcattactgtccgac	CRISPR spacer
aaaattgatttctgagtattactacatcag	Protospacer
***** **********.******.. . *

60. spacer 1.1|2140867|30|NZ_CP028222|CRISPRCasFinder,CRT matches to MH427377 (Escherichia phage vB_EcoM Sa157lw, complete genome) position: , mismatch: 8, identity: 0.733

aaaatggatttctgagcattactgtccgac	CRISPR spacer
aaaattgatttctgagtattactacatcag	Protospacer
***** **********.******.. . *

61. spacer 1.1|2140867|30|NZ_CP028222|CRISPRCasFinder,CRT matches to FQ312032 (Salmonella phage Vi01 complete sequence) position: , mismatch: 8, identity: 0.733

aaaatggatttctgagcattactgtccgac	CRISPR spacer
aaaattgatttctgagtattactacatcag	Protospacer
***** **********.******.. . *

62. spacer 1.1|2140867|30|NZ_CP028222|CRISPRCasFinder,CRT matches to NC_015296 (Salmonella phage Vi01, complete genome) position: , mismatch: 8, identity: 0.733

aaaatggatttctgagcattactgtccgac	CRISPR spacer
aaaattgatttctgagtattactacatcag	Protospacer
***** **********.******.. . *

63. spacer 1.1|2140867|30|NZ_CP028222|CRISPRCasFinder,CRT matches to MN066127 (Salmonella phage Matapan, complete genome) position: , mismatch: 8, identity: 0.733

aaaatggatttctgagcattactgtccgac	CRISPR spacer
aaaattgatttctgagtattactacatcag	Protospacer
***** **********.******.. . *

64. spacer 1.2|2140933|30|NZ_CP028222|CRISPRCasFinder,CRT matches to NC_004349 (Shewanella oneidensis MR-1 megaplasmid, complete sequence) position: , mismatch: 8, identity: 0.733

gactataccaatgaggtcgaagcatggtta	CRISPR spacer
gactgtaccaatgaggtggaagcgccctgt	Protospacer
****.************ *****..  *

65. spacer 1.3|2140999|30|NZ_CP028222|CRISPRCasFinder,CRT matches to NZ_CP032695 (Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525c, complete sequence) position: , mismatch: 8, identity: 0.733

cacaaggccaccgaggaagccggcgagcta	CRISPR spacer
gacgaggccgccgaggaagccggcggcaag	Protospacer
 **.*****.***************.   .

66. spacer 1.3|2140999|30|NZ_CP028222|CRISPRCasFinder,CRT matches to JN106173 (Uncultured bacterium plasmid pAKD31, complete sequence) position: , mismatch: 8, identity: 0.733

cacaaggccaccgaggaagccggcgagcta	CRISPR spacer
gacaacgccaccgaggaggccggccatgac	Protospacer
 **** ***********.****** *

67. spacer 1.3|2140999|30|NZ_CP028222|CRISPRCasFinder,CRT matches to JN106174 (Uncultured bacterium plasmid pAKD33, complete sequence) position: , mismatch: 8, identity: 0.733

cacaaggccaccgaggaagccggcgagcta	CRISPR spacer
gacaacgccaccgaggaggccggccatgac	Protospacer
 **** ***********.****** *

68. spacer 1.3|2140999|30|NZ_CP028222|CRISPRCasFinder,CRT matches to JN106165 (Uncultured bacterium plasmid pAKD14, complete sequence) position: , mismatch: 8, identity: 0.733

cacaaggccaccgaggaagccggcgagcta	CRISPR spacer
gacaacgccaccgaggaggccggccatgac	Protospacer
 **** ***********.****** *

69. spacer 1.3|2140999|30|NZ_CP028222|CRISPRCasFinder,CRT matches to JN106166 (Uncultured bacterium plasmid pAKD15, complete sequence) position: , mismatch: 8, identity: 0.733

cacaaggccaccgaggaagccggcgagcta	CRISPR spacer
gacaacgccaccgaggaggccggccatgac	Protospacer
 **** ***********.****** *

70. spacer 1.3|2140999|30|NZ_CP028222|CRISPRCasFinder,CRT matches to JN106168 (Uncultured bacterium plasmid pAKD17, complete sequence) position: , mismatch: 8, identity: 0.733

cacaaggccaccgaggaagccggcgagcta	CRISPR spacer
gacaacgccaccgaggaggccggccatgac	Protospacer
 **** ***********.****** *

71. spacer 1.3|2140999|30|NZ_CP028222|CRISPRCasFinder,CRT matches to NZ_CP038640 (Cupriavidus oxalaticus strain X32 plasmid unnamed5, complete sequence) position: , mismatch: 8, identity: 0.733

cacaaggccaccgaggaagccggcgagcta	CRISPR spacer
gacaacgccaccgaggaggccggccatgac	Protospacer
 **** ***********.****** *

72. spacer 1.3|2140999|30|NZ_CP028222|CRISPRCasFinder,CRT matches to NZ_CP026526 (Sinorhizobium meliloti strain AK21 plasmid pSymA, complete sequence) position: , mismatch: 8, identity: 0.733

cacaaggccaccgaggaagccggcgagcta	CRISPR spacer
gagaaggccgccgaggaagccggcatgacg	Protospacer
 * ******.**************. * ..

73. spacer 1.3|2140999|30|NZ_CP028222|CRISPRCasFinder,CRT matches to NC_019320 (Variovorax sp. DB1 plasmid pDB1, complete sequence) position: , mismatch: 8, identity: 0.733

cacaaggccaccgaggaagccggcgagcta	CRISPR spacer
gacaacgccaccgaggaggccggccatgac	Protospacer
 **** ***********.****** *

74. spacer 1.3|2140999|30|NZ_CP028222|CRISPRCasFinder,CRT matches to KY676784 (Streptomyces phage ToastyFinz, complete genome) position: , mismatch: 8, identity: 0.733

cacaaggccaccgaggaagccggcgagcta	CRISPR spacer
gcgaaggccgccgaggacgccggcgacgaa	Protospacer
   ******.******* ********   *

75. spacer 1.3|2140999|30|NZ_CP028222|CRISPRCasFinder,CRT matches to KY092482 (Streptomyces phage Mojorita, complete genome) position: , mismatch: 8, identity: 0.733

cacaaggccaccgaggaagccggcgagcta	CRISPR spacer
gagcaggccgccgaggaggccggcgagaag	Protospacer
 *  *****.*******.*********  .

76. spacer 1.3|2140999|30|NZ_CP028222|CRISPRCasFinder,CRT matches to KY092480 (Streptomyces phage Picard, complete genome) position: , mismatch: 8, identity: 0.733

cacaaggccaccgaggaagccggcgagcta	CRISPR spacer
gagcaggccgccgaggaggccggcgagaag	Protospacer
 *  *****.*******.*********  .

77. spacer 1.3|2140999|30|NZ_CP028222|CRISPRCasFinder,CRT matches to NZ_LR134463 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 21, complete sequence) position: , mismatch: 8, identity: 0.733

cacaaggccaccgaggaagccggcgagcta	CRISPR spacer
ttccgcgccgccgagaaagccggcgagctc	Protospacer
. * . ***.*****.*************

78. spacer 1.8|2141329|30|NZ_CP028222|CRISPRCasFinder,CRT matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

ttaggttgagctggatcgggatcaggatcg	CRISPR spacer
gcgggttgagctggaacgggatcaggccga	Protospacer
 ..************ ********** . .

79. spacer 1.9|2141395|30|NZ_CP028222|CRISPRCasFinder,CRT matches to MH617654 (Caudovirales sp. isolate ctbf53, complete genome) position: , mismatch: 8, identity: 0.733

tctgttgtttaatttgttttagattgttac	CRISPR spacer
attgttgtttaatttgtttaacatttacag	Protospacer
 .***************** * ***  .*

80. spacer 1.12|2141593|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to KM879463 (Arthrobacter phage vB_ArtM-ArV1, complete genome) position: , mismatch: 8, identity: 0.733

gcggccacgaccgccatgggtgtcagcgcc	CRISPR spacer
ggtttccaaaccgccatgggtgtcagcacc	Protospacer
*   .*  .******************.**

81. spacer 1.15|2141791|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013110 (Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence) position: , mismatch: 8, identity: 0.733

tcatcaacattttcatcaacgcgactagtt	CRISPR spacer
tgaaattcattttcatcaacgccactaggc	Protospacer
* *    *************** ***** .

82. spacer 1.15|2141791|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to MK496767 (Capybara microvirus Cap3_SP_332, complete genome) position: , mismatch: 8, identity: 0.733

tcatcaacattttcatcaacgcgactagtt	CRISPR spacer
atatcaaaattttcatcaacgcaacgatac	Protospacer
 .***** **************.** *  .

83. spacer 1.20|2142121|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to MT104467 (Pseudomonas phage MR4, complete genome) position: , mismatch: 8, identity: 0.733

acgtctttcagcccagtaaactgctcaagt	CRISPR spacer
agtgacttcagcccattgaactgctcaagc	Protospacer
*    .********* *.***********.

84. spacer 1.20|2142121|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to NC_047802 (Pectobacterium phage PP99, complete genome) position: , mismatch: 8, identity: 0.733

acgtctttcagcccagtaaactgctcaagt	CRISPR spacer
agtgacttcagcccattgaactgctcaagc	Protospacer
*    .********* *.***********.

85. spacer 1.20|2142121|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to KJ749827 (Escherichia phage ECBP5, complete genome) position: , mismatch: 8, identity: 0.733

acgtctttcagcccagtaaactgctcaagt	CRISPR spacer
agtgacttcagcccattgaactgctcaagc	Protospacer
*    .********* *.***********.

86. spacer 1.24|2142385|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to MH616711 (Inoviridae sp. isolate ctbe45, complete genome) position: , mismatch: 8, identity: 0.733

caatcagaaagaagatgacgactataatgc	CRISPR spacer
gtggcagaaagaagatgacgcctatgcttc	Protospacer
  . **************** ****. * *

87. spacer 1.26|2142517|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to NC_015729 (Roseobacter litoralis Och 149 plasmid pRLO149_63, complete sequence) position: , mismatch: 8, identity: 0.733

aactgggagcggtcaacaccccaggctgtg	CRISPR spacer
ttctgggagaggtcaacacccccggcctgc	Protospacer
  ******* ************ ***.

88. spacer 1.26|2142517|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP027408 (Roseobacter denitrificans strain FDAARGOS_309 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

aactgggagcggtcaacaccccaggctgtg	CRISPR spacer
ttctgggagaggtcaacacccccggcctgc	Protospacer
  ******* ************ ***.

89. spacer 1.26|2142517|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026745 (Nocardia cyriacigeorgica strain MDA3349 isolate MDA3349 ancestor plasmid p_unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

aactgggagcggtcaacaccccaggctgtg	CRISPR spacer
gcacaggagcggtcgacaccccgggctgtt	Protospacer
.  ..*********.*******.******

90. spacer 1.26|2142517|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to NC_008387 (Roseobacter denitrificans OCh 114 plasmid pTB2, complete sequence) position: , mismatch: 8, identity: 0.733

aactgggagcggtcaacaccccaggctgtg	CRISPR spacer
ttctgggagaggtcaacacccccggcctgc	Protospacer
  ******* ************ ***.

91. spacer 1.34|2143045|30|NZ_CP028222|CRT matches to NC_018516 (Bacillus thuringiensis HD-789 plasmid pBTHD789-1, complete sequence) position: , mismatch: 8, identity: 0.733

agcataatgtattatgtaacatattatgtt	CRISPR spacer
tacctaatttattttgtaacatattattca	Protospacer
 .* **** **** ************* .

92. spacer 1.34|2143045|30|NZ_CP028222|CRT matches to NZ_CP053970 (Bacillus thuringiensis strain FDAARGOS_796 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

agcataatgtattatgtaacatattatgtt	CRISPR spacer
tacctaatttattttgtaacatattattca	Protospacer
 .* **** **** ************* .

93. spacer 1.34|2143045|30|NZ_CP028222|CRT matches to NZ_CP053979 (Bacillus thuringiensis strain FDAARGOS_795 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.733

agcataatgtattatgtaacatattatgtt	CRISPR spacer
tacctaatttattttgtaacatattattca	Protospacer
 .* **** **** ************* .

94. spacer 1.34|2143045|30|NZ_CP028222|CRT matches to NZ_CP013277 (Bacillus thuringiensis serovar israelensis strain AM65-52 plasmid pAM65-52-2-350K, complete sequence) position: , mismatch: 8, identity: 0.733

agcataatgtattatgtaacatattatgtt	CRISPR spacer
tacctaatttattttgtaacatattattca	Protospacer
 .* **** **** ************* .

95. spacer 1.34|2143045|30|NZ_CP028222|CRT matches to NZ_CP039723 (Bacillus thuringiensis strain BT-59 plasmid p2, complete sequence) position: , mismatch: 8, identity: 0.733

agcataatgtattatgtaacatattatgtt	CRISPR spacer
tacctaatttattttgtaacatattattca	Protospacer
 .* **** **** ************* .

96. spacer 1.34|2143045|30|NZ_CP028222|CRT matches to NZ_CP009348 (Bacillus thuringiensis HD1002 plasmid 2, complete sequence) position: , mismatch: 8, identity: 0.733

agcataatgtattatgtaacatattatgtt	CRISPR spacer
tacctaatttattttgtaacatattattca	Protospacer
 .* **** **** ************* .

97. spacer 1.34|2143045|30|NZ_CP028222|CRT matches to NZ_CP009334 (Bacillus thuringiensis strain HD1011 plasmid 2, complete sequence) position: , mismatch: 8, identity: 0.733

agcataatgtattatgtaacatattatgtt	CRISPR spacer
tacctaatttattttgtaacatattattca	Protospacer
 .* **** **** ************* .

98. spacer 1.34|2143045|30|NZ_CP028222|CRT matches to NZ_CP045024 (Bacillus thuringiensis strain JW-1 plasmid p2, complete sequence) position: , mismatch: 8, identity: 0.733

agcataatgtattatgtaacatattatgtt	CRISPR spacer
tacctaatttattttgtaacatattattca	Protospacer
 .* **** **** ************* .

99. spacer 1.3|2140999|30|NZ_CP028222|CRISPRCasFinder,CRT matches to NZ_CP010801 (Ralstonia mannitolilytica strain SN82F48 plasmid pRMAN01, complete sequence) position: , mismatch: 9, identity: 0.7

cacaaggccaccgaggaagccggcgagcta	CRISPR spacer
atccccttcaccgaggaagccggcgtgctc	Protospacer
  *    .***************** ***

100. spacer 1.3|2140999|30|NZ_CP028222|CRISPRCasFinder,CRT matches to NC_008269 (Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence) position: , mismatch: 9, identity: 0.7

cacaaggccaccgaggaagccggcgagcta	CRISPR spacer
aagcgcgccaccgaggatgccggcgagggc	Protospacer
 *  . *********** *********

101. spacer 1.7|2141263|30|NZ_CP028222|CRISPRCasFinder,CRT matches to MN693509 (Marine virus AFVG_25M367, complete genome) position: , mismatch: 9, identity: 0.7

aactcatcataaatgacgtcttttaccgag	CRISPR spacer
tcatcatcataaacgacttcttttactcct	Protospacer
   **********.*** ********.

102. spacer 1.7|2141263|30|NZ_CP028222|CRISPRCasFinder,CRT matches to NZ_CP012101 (Bacillus thuringiensis strain HS18-1 plasmid pHS18-2, complete sequence) position: , mismatch: 9, identity: 0.7

aactcatcataaatgacgtcttttaccgag	CRISPR spacer
tcatcatcataaatggcgtcttttttttat	Protospacer
   ************.******** .. *

103. spacer 1.14|2141725|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP029457 (Bacillus cereus strain FORC087 plasmid pFORC087.3, complete sequence) position: , mismatch: 9, identity: 0.7

taccgggtgttaaatctgaattagaagcgc	CRISPR spacer
ttgatggtgttaaatctcaattagaaaatt	Protospacer
*    ************ ********.  .

104. spacer 1.20|2142121|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP032091 (Pseudoalteromonas donghaensis strain HJ51 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.7

acgtctttcagcccagtaaactgctcaagt	CRISPR spacer
ttaaataagagcccaggaaactgctcaagt	Protospacer
 ..  *   ******* *************

105. spacer 1.25|2142451|30|NZ_CP028222|CRISPRCasFinder,CRT,PILER-CR matches to MN582058 (Caudovirales sp. ctOwN3, complete genome) position: , mismatch: 9, identity: 0.7

gacttataccagcagtaccgaagacggtta	CRISPR spacer
actagataccagcagtaccgaatacggcac	Protospacer
. .  ***************** ****.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

28351 : 40317

Lactobacillus_phage(87.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003643099.1\|28351_29299_-	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	2.7e-178	100.0
WP_003643097.1\|29642_30257_+	NAD(P)H-dependent oxidoreductase	A0A2P0ZL77	Lactobacillus_phage	6.3e-112	100.0
WP_063720948.1\|30259_32698_+	flavocytochrome c	A0A2P0ZL82	Lactobacillus_phage	0.0e+00	99.8
WP_003643095.1\|32785_33346_+	hypothetical protein	A0A2P0ZL75	Lactobacillus_phage	2.7e-101	100.0
WP_003643094.1\|33416_33857_-	nucleoside 2-deoxyribosyltransferase	A0A2P0ZL88	Lactobacillus_phage	8.0e-77	99.3
WP_052098033.1\|34201_34669_+	hypothetical protein	A0A2P0ZL91	Lactobacillus_phage	6.1e-83	99.4
WP_053566592.1\|34643_35618_+	hypothetical protein	A0A2P0ZL95	Lactobacillus_phage	5.0e-31	90.7
WP_047673279.1\|35721_35931_+	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_003640226.1\|38043_40317_-	HAD-IC family P-type ATPase	M1HX51	Paramecium_bursaria_Chlorella_virus	1.3e-37	23.5

DBSCAN-SWA_2

516736 : 578086

Lactobacillus_phage(17.65%)

transposase,protease,integrase,tRNA

attL 558627:558644|attR 584909:584926

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003644485.1\|516736_517891_+\|integrase	site-specific integrase	A0A0A8WIE1	Clostridium_phage	2.5e-98	44.7
WP_003640703.1\|518007_519843_-	elongation factor 4	E4ZFJ7	Streptococcus_phage	1.5e-23	26.1
WP_003640704.1\|520006_521284_-	D-alanyl-lipoteichoic acid biosynthesis protein DltD	NA	NA	NA	NA
WP_003640705.1\|521280_521523_-	D-alanine--poly(phosphoribitol) ligase subunit DltC	NA	NA	NA	NA
WP_003640706.1\|521546_522761_-	D-alanyl-lipoteichoic acid biosynthesis protein DltB	A0A125RNP0	Pseudomonas_phage	1.9e-27	30.5
WP_003640707.1\|522757_524284_-	D-alanine--poly(phosphoribitol) ligase subunit DltA	A0A2K9KZV5	Tupanvirus	7.6e-42	27.6
WP_003640708.1\|524326_524476_-	teichoic acid D-Ala incorporation-associated protein DltX	NA	NA	NA	NA
WP_003645971.1\|524507_525683_-	serine hydrolase	NA	NA	NA	NA
WP_003640710.1\|526116_527259_-	molecular chaperone DnaJ	A0A2K9L588	Tupanvirus	4.3e-21	32.0
WP_003640711.1\|527360_529229_-	molecular chaperone DnaK	A0A2P1EIW2	Megavirus	7.7e-137	47.2
WP_013355604.1\|529272_529872_-	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_003640713.1\|529892_530936_-	heat-inducible transcriptional repressor HrcA	NA	NA	NA	NA
WP_003640714.1\|531326_532037_-	acetolactate decarboxylase	NA	NA	NA	NA
WP_003640715.1\|532037_533039_-	riboflavin biosynthesis protein RibF	NA	NA	NA	NA
WP_003640716.1\|533051_533975_-\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
WP_063722225.1\|534452_534974_-	shikimate kinase	NA	NA	NA	NA
WP_063722224.1\|534976_536074_-	prephenate dehydrogenase	NA	NA	NA	NA
WP_160249471.1\|536076_537375_-	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_003645964.1\|537388_537916_-	amino acid biosynthesis protein	NA	NA	NA	NA
WP_013355607.1\|537924_539094_-	chorismate synthase	NA	NA	NA	NA
WP_015825652.1\|539086_540541_-	MFS transporter	NA	NA	NA	NA
WP_003640723.1\|541189_541543_-	30S ribosome-binding factor RbfA	NA	NA	NA	NA
WP_024002734.1\|541565_544142_-	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	9.6e-21	23.3
WP_063722223.1\|544156_544462_-	hypothetical protein	NA	NA	NA	NA
WP_024002733.1\|544451_544751_-	YlxR family protein	NA	NA	NA	NA
WP_024002732.1\|544795_546013_-	transcription termination/antitermination protein NusA	NA	NA	NA	NA
WP_063722222.1\|546033_546510_-	ribosome maturation factor RimP	NA	NA	NA	NA
WP_003640729.1\|546805_551119_-	DNA polymerase III subunit alpha	A0A1X9SH08	Bradyrhizobium_phage	1.0e-14	34.0
WP_003640732.1\|551612_553322_-\|tRNA	proline--tRNA ligase	NA	NA	NA	NA
WP_003640733.1\|553361_554639_-\|protease	RIP metalloprotease RseP	NA	NA	NA	NA
WP_003640734.1\|554676_555462_-	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_046039550.1\|555477_556257_-	isoprenyl transferase	R9W0U9	Flavobacterium_phage	6.9e-23	42.3
WP_003640736.1\|556376_556940_-	ribosome recycling factor	NA	NA	NA	NA
WP_003640737.1\|556941_557664_-	UMP kinase	NA	NA	NA	NA
WP_003644498.1\|557864_558743_-	elongation factor Ts	NA	NA	NA	NA
558627:558644	attL	NA	NA	NA	NA
WP_003640739.1\|558845_559649_-	30S ribosomal protein S2	NA	NA	NA	NA
WP_003640740.1\|559873_560596_+	HAD family hydrolase	NA	NA	NA	NA
WP_003640741.1\|560884_561883_-	D-2-hydroxyacid dehydrogenase	M1HKI4	Acanthocystis_turfacea_Chlorella_virus	2.3e-47	34.9
WP_003640742.1\|561967_562273_-	GIY-YIG nuclease family protein	NA	NA	NA	NA
WP_003644499.1\|562256_563015_-\|tRNA	tRNA1(Val) (adenine(37)-N6)-methyltransferase	NA	NA	NA	NA
WP_003645630.1\|563126_563762_+	1-acyl-sn-glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
WP_003640745.1\|563818_564055_-	YneF family protein	NA	NA	NA	NA
WP_003644501.1\|564152_564392_-	DUF896 domain-containing protein	NA	NA	NA	NA
WP_003640747.1\|564543_565176_+	transcriptional repressor LexA	A0A1B2APZ1	Phage_Wrath	2.3e-16	56.2
WP_157262971.1\|565264_565357_-	hypothetical protein	NA	NA	NA	NA
WP_003644502.1\|565730_566360_+	hypothetical protein	NA	NA	NA	NA
WP_063722221.1\|566409_567579_-	hydroxymethylglutaryl-CoA synthase	NA	NA	NA	NA
WP_063722220.1\|567614_568007_-	hypothetical protein	NA	NA	NA	NA
WP_003644503.1\|568170_568563_+	hypothetical protein	NA	NA	NA	NA
WP_003644504.1\|569007_569949_+	glycosyltransferase family 2 protein	V9QJB1	Oenococcus_phage	2.4e-78	49.0
WP_024002729.1\|570706_570958_+	DUF4428 domain-containing protein	NA	NA	NA	NA
WP_003640755.1\|571179_571563_+	hypothetical protein	O48432	Lactobacillus_phage	4.7e-09	27.4
WP_071665389.1\|571707_573573_+	DUF4428 domain-containing protein	O48432	Lactobacillus_phage	3.9e-16	26.0
WP_050495869.1\|573589_574192_+	DUF4428 domain-containing protein	NA	NA	NA	NA
WP_079994877.1\|574586_574844_-\|transposase	IS3 family transposase	A0A0C5AEA5	Paenibacillus_phage	7.6e-11	42.7
WP_015825666.1\|574975_575392_-\|transposase	IS3 family transposase	A0A0C5AC89	Paenibacillus_phage	9.1e-06	35.0
WP_063722215.1\|575451_575919_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_077726998.1\|576166_576556_+\|transposase	transposase	NA	NA	NA	NA
WP_024003070.1\|576922_578086_+\|integrase	site-specific integrase	E9LUK6	Lactobacillus_phage	1.5e-61	38.2
584909:584926	attR	NA	NA	NA	NA

DBSCAN-SWA_3

877081 : 921039

Lactobacillus_phage(36.84%)

portal,integrase,protease,holin,terminase,tail

attL 874428:874444|attR 921264:921280

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
874428:874444	attL	NA	NA	NA	NA
WP_033611967.1\|877081_877465_-\|holin	holin	A0A2H4PBB2	Lactobacillus_phage	9.9e-15	80.0
WP_027821934.1\|877451_877748_-	hypothetical protein	A0A2K9VCD4	Lactobacillus_phage	2.4e-37	73.5
WP_160249564.1\|877748_878882_-	LysM peptidoglycan-binding domain-containing protein	O03950	Lactobacillus_phage	1.4e-32	76.8
WP_021732622.1\|879042_879477_-	hypothetical protein	NA	NA	NA	NA
WP_046811036.1\|879479_879929_-	DUF1617 family protein	A0A2P0ZLE0	Lactobacillus_phage	2.8e-21	40.5
WP_160249477.1\|879950_885314_-	hypothetical protein	Q6SE68	Lactobacillus_prophage	5.4e-143	59.1
WP_099739626.1\|885328_885661_-	hypothetical protein	V5UQS8	Oenococcus_phage	2.2e-42	73.4
WP_160249478.1\|885704_891536_-\|tail	phage tail protein	V5URV5	Oenococcus_phage	1.1e-229	40.8
WP_033612158.1\|891551_891809_-	hypothetical protein	V9QKH3	Oenococcus_phage	1.6e-21	65.0
WP_056988502.1\|891916_892315_-	hypothetical protein	V9QJA0	Oenococcus_phage	4.3e-45	74.4
WP_080499809.1\|892414_892891_-\|tail	phage tail protein	V5USQ9	Oenococcus_phage	3.0e-45	60.4
WP_033611975.1\|892899_893265_-	hypothetical protein	V5UQS4	Oenococcus_phage	3.0e-29	54.2
WP_033612159.1\|893264_893816_-	HK97 gp10 family phage protein	V5URV0	Oenococcus_phage	1.8e-65	62.3
WP_033611976.1\|893808_894168_-	hypothetical protein	V5US85	Oenococcus_phage	1.5e-33	57.6
WP_160249479.1\|894167_894500_-	hypothetical protein	V9QJ97	Oenococcus_phage	1.2e-11	43.2
WP_044431356.1\|894511_894688_-	hypothetical protein	NA	NA	NA	NA
WP_003642819.1\|894700_895723_-	hypothetical protein	V5US24	Oenococcus_phage	3.7e-117	62.5
WP_021356223.1\|895742_896093_-	hypothetical protein	V5UTH9	Oenococcus_phage	2.2e-29	61.9
WP_003642817.1\|896107_896785_-	DUF4355 domain-containing protein	Q6SE80	Lactobacillus_prophage	6.4e-17	33.5
WP_003642816.1\|896957_897164_-	hypothetical protein	NA	NA	NA	NA
WP_003642815.1\|897215_897494_-	hypothetical protein	NA	NA	NA	NA
WP_021356225.1\|897468_899154_-	hypothetical protein	V5US81	Oenococcus_phage	3.1e-121	59.1
WP_021356226.1\|899300_899597_-\|protease	ribosomal-processing cysteine protease Prp	D2J003	Enterococcus_phage	5.6e-10	39.2
WP_160249480.1\|899526_901035_-\|portal	phage portal protein	V5US18	Oenococcus_phage	1.1e-136	52.0
WP_024002529.1\|901046_902285_-\|terminase	PBSX family phage terminase large subunit	M1PG09	Streptococcus_phage	1.4e-139	61.3
WP_024002530.1\|902274_902802_-\|terminase	terminase small subunit	O03926	Lactobacillus_phage	3.5e-55	73.4
WP_021732633.1\|902843_903113_-	DUF2829 domain-containing protein	A0A0K2FLC4	Brevibacillus_phage	2.5e-12	45.5
WP_015380624.1\|903240_903438_-	hypothetical protein	NA	NA	NA	NA
WP_063096770.1\|904505_904967_-	transcriptional regulator	D6PSV8	Lactobacillus_phage	6.3e-40	57.0
WP_071665406.1\|905177_905558_-	endodeoxyribonuclease	NA	NA	NA	NA
WP_160249481.1\|905554_906073_-	hypothetical protein	O03915	Lactobacillus_phage	3.3e-53	68.4
WP_003642800.1\|906069_906357_-	hypothetical protein	NA	NA	NA	NA
WP_160249482.1\|906353_907262_-	DnaD domain protein	NA	NA	NA	NA
WP_080373216.1\|907340_908213_-	hypothetical protein	A0A0P0IZH9	Lactobacillus_phage	1.9e-74	50.8
WP_003642797.1\|908124_909024_-	recombinase RecT	E9LUM3	Lactobacillus_phage	3.2e-64	53.7
WP_160249483.1\|909020_909407_-	hypothetical protein	NA	NA	NA	NA
WP_072533950.1\|909539_909710_-	hypothetical protein	NA	NA	NA	NA
WP_160249484.1\|909767_910013_-	hypothetical protein	NA	NA	NA	NA
WP_003642794.1\|910028_910541_-	helix-turn-helix transcriptional regulator	D6PST4	Lactobacillus_phage	8.0e-28	43.5
WP_003642793.1\|910608_910914_-	DUF771 domain-containing protein	NA	NA	NA	NA
WP_011101086.1\|911254_911455_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_011101085.1\|911601_911838_+	helix-turn-helix transcriptional regulator	A0A0K2CNE2	Brevibacillus_phage	8.5e-09	30.7
WP_003642787.1\|911875_912190_+	hypothetical protein	NA	NA	NA	NA
WP_011101083.1\|912262_912493_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_011101082.1\|912666_913029_+	helix-turn-helix domain-containing protein	A0A0U4KKM4	Exiguobacterium_phage	2.6e-09	32.0
WP_003644968.1\|913040_913454_+	ImmA/IrrE family metallo-endopeptidase	A0A0M4RD70	Bacillus_phage	3.4e-05	31.3
WP_069302546.1\|913479_914826_+	DUF4041 domain-containing protein	A0A1B0Y697	Lactobacillus_phage	6.7e-82	52.7
WP_062690021.1\|914875_915436_+	DUF5067 domain-containing protein	Q6SEF8	Lactobacillus_prophage	4.6e-45	65.9
WP_062690023.1\|915490_915826_+	hypothetical protein	A0A1B0Y4P2	Lactobacillus_phage	1.9e-25	52.2
WP_024002855.1\|916302_917094_+	hypothetical protein	NA	NA	NA	NA
WP_016527215.1\|917103_917358_+	hypothetical protein	NA	NA	NA	NA
WP_024002853.1\|917436_917811_+	hypothetical protein	A0A0P0I7G8	Lactobacillus_phage	1.9e-34	65.8
WP_021356370.1\|918522_918951_+	hypothetical protein	Q6SEA3	Lactobacillus_prophage	2.5e-27	41.1
WP_107724279.1\|918986_919778_+	DUF1828 domain-containing protein	Q6SEA4	Lactobacillus_prophage	8.5e-61	45.4
WP_021356369.1\|919917_921039_+\|integrase	site-specific integrase	D6PSS4	Lactobacillus_phage	3.7e-46	32.4
921264:921280	attR	NA	NA	NA	NA

DBSCAN-SWA_4

1125142 : 1133656

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003642593.1\|1125142_1125721_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.9e-22	35.0
WP_003642592.1\|1125713_1126739_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F760	Synechococcus_phage	8.4e-61	41.7
WP_003642591.1\|1126735_1128190_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	2.5e-50	34.0
WP_021356102.1\|1128174_1130394_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	3.5e-144	39.1
WP_021356103.1\|1130386_1131067_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_003642588.1\|1131066_1131321_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_021356104.1\|1131322_1132054_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4SM18	Cyanophage	2.1e-37	37.3
WP_024521791.1\|1132056_1133187_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_003642585.1\|1133170_1133656_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	2.3e-16	41.0

DBSCAN-SWA_5

1998885 : 2059227

Streptococcus_phage(18.75%)

portal,integrase,capsid,head,terminase,tRNA

attL 2047170:2047196|attR 2052156:2052182

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047674460.1\|1998885_2000796_-\|tRNA	tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG	NA	NA	NA	NA
WP_003641622.1\|2000814_2002206_-\|tRNA	tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE	NA	NA	NA	NA
WP_015379588.1\|2002437_2003406_-	KH domain-containing protein	NA	NA	NA	NA
WP_011102291.1\|2003891_2005145_-	amidohydrolase family protein	NA	NA	NA	NA
WP_047674465.1\|2005277_2006915_-	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_003641627.1\|2007629_2008463_-	membrane protein insertase YidC	NA	NA	NA	NA
WP_003640224.1\|2008478_2008823_-	ribonuclease P protein component	NA	NA	NA	NA
WP_003640225.1\|2008933_2009068_-	50S ribosomal protein L34	NA	NA	NA	NA
WP_003641628.1\|2009573_2010941_+	chromosomal replication initiator protein DnaA	NA	NA	NA	NA
WP_003641629.1\|2011118_2012258_+	DNA polymerase III subunit beta	D0R7I4	Paenibacillus_phage	4.3e-13	29.9
WP_003641630.1\|2012782_2013016_+	S4 domain-containing protein YaaA	NA	NA	NA	NA
WP_003641631.1\|2013016_2014141_+	DNA replication/repair protein RecF	NA	NA	NA	NA
WP_003641632.1\|2014137_2016084_+	DNA topoisomerase (ATP-hydrolyzing) subunit B	G3M9Z3	Bacillus_virus	5.5e-146	46.7
WP_160249513.1\|2016248_2018801_+	DNA gyrase subunit A	G3M9Z5	Bacillus_virus	8.1e-113	37.3
WP_003637271.1\|2019423_2019723_+	30S ribosomal protein S6	NA	NA	NA	NA
WP_003641634.1\|2019759_2020362_+	single-stranded DNA-binding protein	A0A218MNB4	uncultured_virus	3.7e-40	72.1
WP_003641635.1\|2020400_2020637_+	30S ribosomal protein S18	NA	NA	NA	NA
WP_003643610.1\|2020817_2022830_+	DHH family phosphoesterase	NA	NA	NA	NA
WP_003641637.1\|2022842_2023295_+	50S ribosomal protein L9	NA	NA	NA	NA
WP_003641638.1\|2023310_2024735_+	replicative DNA helicase	A0A1P8VVQ6	Streptococcus_phage	9.7e-124	53.1
WP_003641639.1\|2024956_2026180_+	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	2.4e-54	33.6
WP_003643611.1\|2026201_2026999_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.0e-45	39.2
WP_063721953.1\|2027017_2028256_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	1.8e-110	52.6
WP_003641642.1\|2028716_2030333_+	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_160249514.1\|2030663_2032568_+	1,4-alpha-glucan branching protein GlgB	NA	NA	NA	NA
WP_063721952.1\|2032557_2033697_+	glucose-1-phosphate adenylyltransferase	NA	NA	NA	NA
WP_003641646.1\|2033693_2034866_+	glucose-1-phosphate adenylyltransferase subunit GlgD	NA	NA	NA	NA
WP_063721951.1\|2034858_2036298_+	glycogen synthase GlgA	NA	NA	NA	NA
WP_063721950.1\|2038730_2040548_+	glycoside hydrolase family 13 protein	NA	NA	NA	NA
WP_063721949.1\|2040880_2041648_+	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_063721948.1\|2041799_2042471_-	beta-phosphoglucomutase	NA	NA	NA	NA
WP_033609078.1\|2042488_2045209_-	glycoside hydrolase family 65 protein	NA	NA	NA	NA
WP_003641653.1\|2045586_2046036_-	pyridoxamine 5'-phosphate oxidase family protein	NA	NA	NA	NA
WP_003643615.1\|2046233_2046434_+	cold-shock protein	Q9AZD3	Lactococcus_phage	2.8e-21	74.6
WP_003641655.1\|2046525_2046750_+	hypothetical protein	NA	NA	NA	NA
2047170:2047196	attL	NA	NA	NA	NA
WP_160249515.1\|2047217_2048372_-\|integrase	site-specific integrase	A0A172LN96	Lactococcus_phage	8.0e-60	36.7
WP_057705756.1\|2048433_2049138_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_041153480.1\|2049276_2049456_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_160249516.1\|2049498_2049606_+	hypothetical protein	NA	NA	NA	NA
WP_160249517.1\|2049738_2049957_+	hypothetical protein	NA	NA	NA	NA
WP_160249518.1\|2049953_2050754_+	DNA replication protein	NA	NA	NA	NA
WP_160249519.1\|2050753_2052148_+	virulence protein	A0A0A7RTG3	Clostridium_phage	6.7e-69	33.9
WP_160249520.1\|2052221_2052701_+	hypothetical protein	NA	NA	NA	NA
2052156:2052182	attR	NA	NA	NA	NA
WP_148419183.1\|2052715_2052907_+	hypothetical protein	NA	NA	NA	NA
WP_160249521.1\|2052893_2053232_+\|head	phage head closure protein	A0A2P0ZLF0	Lactobacillus_phage	4.2e-09	36.6
WP_160249522.1\|2053224_2053614_+	HNH endonuclease	A0A1J0MFT4	Staphylococcus_phage	3.9e-19	45.2
WP_160249523.1\|2054228_2054702_+\|terminase	phage terminase small subunit P27 family	NA	NA	NA	NA
WP_160249524.1\|2054698_2056402_+\|terminase	terminase large subunit	A0A2H4JBN3	uncultured_Caudovirales_phage	6.4e-122	41.1
WP_080392743.1\|2056355_2056556_+	hypothetical protein	NA	NA	NA	NA
WP_160249525.1\|2056556_2057663_+\|portal	phage portal protein	A0A2H4J9Q5	uncultured_Caudovirales_phage	3.6e-49	33.6
WP_160249526.1\|2057652_2059227_+\|capsid	phage major capsid protein	A0A1J0MFW8	Staphylococcus_phage	9.6e-40	34.6

DBSCAN-SWA_6

2355899 : 2405861

Bacillus_virus(50.0%)

protease,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003643762.1\|2355899_2356463_-\|protease	matrixin family metalloprotease	NA	NA	NA	NA
WP_011100974.1\|2356656_2357325_+	ribose 5-phosphate isomerase A	NA	NA	NA	NA
WP_160249541.1\|2357474_2358980_+	multicopper oxidase domain-containing protein	NA	NA	NA	NA
WP_003643763.1\|2359244_2359613_+	DUF1304 domain-containing protein	NA	NA	NA	NA
WP_003641932.1\|2359725_2360235_-	YbhB/YbcL family Raf kinase inhibitor-like protein	NA	NA	NA	NA
WP_024521227.1\|2360265_2361462_-	DUF2075 domain-containing protein	NA	NA	NA	NA
WP_003646440.1\|2361571_2362042_+	Rrf2 family transcriptional regulator	NA	NA	NA	NA
WP_003641935.1\|2362060_2362516_+	hypothetical protein	NA	NA	NA	NA
WP_003641936.1\|2362619_2363192_+	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit	NA	NA	NA	NA
WP_044428959.1\|2363357_2364278_-	ribonucleoside hydrolase RihC	NA	NA	NA	NA
WP_015825107.1\|2364414_2365314_+	oxidoreductase	NA	NA	NA	NA
WP_160249542.1\|2365753_2367634_+	hypothetical protein	NA	NA	NA	NA
WP_011100980.1\|2367805_2368252_-	ribonuclease H	NA	NA	NA	NA
WP_003643770.1\|2368489_2370016_+	ABC transporter permease/substrate-binding protein	NA	NA	NA	NA
WP_003641941.1\|2370016_2370988_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.7e-23	31.7
WP_003646444.1\|2371065_2372397_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_003643773.1\|2372862_2374380_+	glycerol kinase GlpK	NA	NA	NA	NA
WP_003643774.1\|2374394_2376224_+	type 1 glycerol-3-phosphate oxidase	NA	NA	NA	NA
WP_003641945.1\|2376238_2376961_+	aquaporin family protein	M1HWZ0	Paramecium_bursaria_Chlorella_virus	3.2e-30	31.9
WP_063722046.1\|2377547_2381243_+	MucBP domain-containing protein	NA	NA	NA	NA
WP_033608293.1\|2383054_2383447_+	hypothetical protein	NA	NA	NA	NA
WP_033608294.1\|2385130_2385403_+	hypothetical protein	NA	NA	NA	NA
WP_050495849.1\|2385784_2385985_+	hypothetical protein	NA	NA	NA	NA
WP_053566430.1\|2386242_2386476_+	hypothetical protein	NA	NA	NA	NA
WP_003643792.1\|2386604_2387024_+	hypothetical protein	NA	NA	NA	NA
WP_033608295.1\|2387315_2387780_+	hypothetical protein	NA	NA	NA	NA
WP_015379760.1\|2388058_2388676_-	sugar O-acetyltransferase	NA	NA	NA	NA
WP_063722044.1\|2388679_2389834_-	MFS transporter	NA	NA	NA	NA
WP_011100993.1\|2389837_2390629_-	HAD family hydrolase	NA	NA	NA	NA
WP_003641965.1\|2390699_2391572_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_053566435.1\|2391731_2392547_+	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_003643798.1\|2393072_2394449_+	branched-chain amino acid transport system II carrier protein	NA	NA	NA	NA
WP_033608300.1\|2394493_2395678_+	cation:proton antiporter	NA	NA	NA	NA
WP_003643800.1\|2396338_2396482_+	hypothetical protein	NA	NA	NA	NA
WP_050495850.1\|2396493_2396682_+	hypothetical protein	NA	NA	NA	NA
WP_071665317.1\|2396951_2397158_-	hypothetical protein	NA	NA	NA	NA
WP_080029873.1\|2397127_2397457_-	hypothetical protein	NA	NA	NA	NA
WP_117288141.1\|2397563_2397767_-	hypothetical protein	NA	NA	NA	NA
WP_003643802.1\|2397922_2398438_+	Na+/H+ antiporter	NA	NA	NA	NA
WP_003641969.1\|2398642_2398846_+	hypothetical protein	NA	NA	NA	NA
WP_003643803.1\|2399080_2399233_-	hypothetical protein	NA	NA	NA	NA
WP_003643805.1\|2399257_2399926_-	hypothetical protein	NA	NA	NA	NA
WP_003641972.1\|2399922_2400096_-\|bacteriocin	two-peptide bacteriocin plantaricin JK subunit PlnK	NA	NA	NA	NA
WP_003641973.1\|2400126_2400294_-\|bacteriocin	two-peptide bacteriocin plantaricin JK subunit PlnJ	NA	NA	NA	NA
WP_003643806.1\|2401400_2402147_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_003643807.1\|2402278_2402428_+	hypothetical protein	NA	NA	NA	NA
WP_003643808.1\|2402441_2403782_+	GHKL domain-containing protein	NA	NA	NA	NA
WP_003643809.1\|2403782_2404526_+	response regulator transcription factor	NA	NA	NA	NA
WP_003643810.1\|2404830_2405604_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_003643811.1\|2405702_2405861_-\|bacteriocin	two-peptide bacteriocin plantaricin EF subunit PlnF	NA	NA	NA	NA

DBSCAN-SWA_7

2598665 : 2607289

Streptococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003644909.1\|2598665_2600363_+	DNA polymerase III subunit gamma/tau	A0A1U9WR94	Streptococcus_virus	3.9e-55	37.0
WP_003640956.1\|2600384_2600693_+	YbaB/EbfC family nucleoid-associated protein	NA	NA	NA	NA
WP_003637790.1\|2600708_2601308_+	recombination protein RecR	NA	NA	NA	NA
WP_003640957.1\|2601322_2601574_+	YaaL family protein	NA	NA	NA	NA
WP_011101140.1\|2601971_2602637_+	dTMP kinase	M1PSC7	Streptococcus_phage	1.4e-53	52.7
WP_003640965.1\|2602633_2602963_+	hypothetical protein	NA	NA	NA	NA
WP_063722355.1\|2602979_2603999_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	2.1e-32	33.5
WP_003640967.1\|2604023_2604371_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	2.4e-12	33.3
WP_003643942.1\|2604469_2605366_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	9.9e-82	55.7
WP_160249549.1\|2605369_2606155_+	acyl-ACP thioesterase	NA	NA	NA	NA
WP_013355240.1\|2606293_2607289_+	UDP-glucose 4-epimerase GalE	A0A2K9L5H6	Tupanvirus	2.0e-51	38.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP028224

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1486 : 11575

Paenibacillus_phage(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_112260613.1\|1486_2261_+\|transposase	IS5-like element ISLpl3 family transposase	A0A0N9SHJ4	Paenibacillus_phage	2.1e-27	53.2
WP_013356282.1\|2346_3501_-	cation:proton antiporter	NA	NA	NA	NA
WP_160249573.1\|3871_4647_-\|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	3.5e-27	52.3
WP_013356283.1\|4754_5657_-	YitT family protein	M1Q1P6	Streptococcus_phage	6.3e-52	40.3
WP_046783566.1\|5743_6376_-	recombinase family protein	A0A286S1P7	Klebsiella_phage	3.6e-14	33.2
WP_112260612.1\|6489_7302_+\|transposase	IS3 family transposase	Q6J1X2	Lactobacillus_phage	6.3e-11	29.5
WP_160249574.1\|7429_8380_-	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A096XT60	Enterococcus_phage	1.8e-97	54.0
WP_010623241.1\|8394_9321_-	ribonucleoside-diphosphate reductase subunit beta	A0A2H4P8A9	Corynebacterium_phage	5.9e-37	32.1
WP_029508458.1\|9427_11575_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	9.4e-256	60.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP028223

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP028222

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_CP028224

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection