CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP047964	Aeromonas media strain MC64 plasmid pMC64B, complete sequence	0 crisprs	NA	0	0	2	0
NZ_CP047963	Aeromonas media strain MC64 plasmid pMC64A, complete sequence	2 crisprs	c2c9_V-U4,cas14j,DinG,cas2,cas1,cmr1gr7,cas10,cmr3gr5,cmr4gr7,cmr5gr11,cmr6gr7,cas6,csx1,csx16,WYL,PD-DExK	0	25	4	1
NZ_CP047962	Aeromonas media strain MC64 chromosome, complete genome	8 crisprs	DinG,csa3,DEDDh,c2c9_V-U4,cas14j,WYL,cas3	1	1	25	5

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 5426

Salmonella_phage(50.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001162010.1\|2051_2609_-	recombinase family protein	A0A1B0V7I5	Salmonella_phage	3.4e-48	81.3
WP_042201119.1\|2739_4227_-	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_003056106.1\|4213_4687_-	cytochrome c	NA	NA	NA	NA
WP_004393997.1\|4715_5426_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.7e-31	38.3

DBSCAN-SWA_2

9998 : 13531

uncultured_Caudovirales_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_042044880.1\|9998_10628_-	AAA family ATPase	K7R2R7	Vibrio_phage	4.5e-49	51.2
WP_161508013.1\|10915_10999_-	ParA family protein	NA	NA	NA	NA
WP_101617265.1\|11203_11491_+	ribbon-helix-helix protein, CopG family	NA	NA	NA	NA
WP_101617266.1\|11478_11772_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_161508008.1\|12620_12962_-	type II toxin-antitoxin system CcdA family antitoxin	NA	NA	NA	NA
WP_113722067.1\|13011_13299_-	type II toxin-antitoxin system RelE/ParE family toxin	A0A2H4JBF4	uncultured_Caudovirales_phage	3.0e-32	75.8
WP_026080514.1\|13288_13531_-	type II toxin-antitoxin system RelB/DinJ family antitoxin	A0A2H4JBG1	uncultured_Caudovirales_phage	1.9e-19	58.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP047963

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP047963_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047963_1

58641-60361

TypeIII

Consensus_repeat	Method
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	CRISPRCasFinder
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	CRT
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	PILER-CR

24 spacers

DinG,cas2,cas1,cmr1gr7,cas10,cmr3gr5

The CRISPR arrays of NZ_CP047963_1

>merge|NZ_CP047963|1|58641-60361|CRISPRCasFinder,CRT,PILER-CR
CCGCGAAGAACCTTATTAGCAGGGCGAACTTCTGACAGATATGTATGAAGCATTGTTGGCGGGTCTTTTGGACGTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGACTATGAGGGATTGGTAGCGGCGGCTAGAAAAAATGTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGACAATAGGTAACCCCTATGCGAATACTCAACACATAGTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGACGAATTGTTTAGCCTCAAGAGTCAACTTGGGGCTCTGTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGACAAAGCAATCCTTCAGTCCATCTGATGCATAACCGTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGACCGTCGAGAAATCTCTCGACGAACCTGAGGAGCCTAAGGTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGACTGATATATTCGACTCATTGGATTTGTACATATGGATAGTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGACACTGGGTTACTGGAACCCTCGTGGAATCATTACTGCGTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGACAGTAGAGGAGCATTGCCTCACTCTGCTGACAATGTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGACCACTGTTCGCACTCACCTTCATCACCATAATCGTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGACAAACTATAGCTAGCAAGCTAGCCACACGACTCAGTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGACACAGGAGAAAGACATGAGGTTATTACCAGTACATACGTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGACTCACGTGGTCTTACCATCCAACAAGCCATTGGTTCTGGGTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGACAAAATACATCCTCGAAGCAGCAATCGAGGTAGCGTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGACGGTATCTTTGGTGCTGTATCCTCTACCACTGTGTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGACTAACTCCGCTGCTTCCCTGATTGCTGCTGCTATGTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGACACTTGGCTCATGCAGCCAACAACTACTCCCTGTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGACATCATCCGGCACAAGGGGCGTGTGTATGCTCCGTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGACTATCAAGGTTCGTTGTCTCAATTGATTCTGCTGTGTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGACATCACTGACTGTCGTGTCACTAAAGTGCTGGACGTGTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGACGTTTGTATCTCTGCCATTCGGGCTTCCCCTTGATACGTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGACTTCCTTCAATGGCGTGAAAGCCAAGGAAGTGCGTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGACGTACCAGAACATCCATTCCTTACTCTTGGCTCCCGTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGACTTTACCGTATGGTCTGCCATTGGATACCATGACCAGTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC

>NZ_CP047963|1|1|58641-60361|CRISPRCasFinder
CCGCGAAGAACCTTATTAGCAGGGCGAACTTCTGAC	AGATATGTATGAAGCATTGTTGGCGGGTCTTTTGGAC
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	TATGAGGGATTGGTAGCGGCGGCTAGAAAAAAT
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	AATAGGTAACCCCTATGCGAATACTCAACACATA
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	GAATTGTTTAGCCTCAAGAGTCAACTTGGGGCTCT
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	AAAGCAATCCTTCAGTCCATCTGATGCATAACC
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	CGTCGAGAAATCTCTCGACGAACCTGAGGAGCCTAAG
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	TGATATATTCGACTCATTGGATTTGTACATATGGATA
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	ACTGGGTTACTGGAACCCTCGTGGAATCATTACTGC
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	AGTAGAGGAGCATTGCCTCACTCTGCTGACAAT
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	CACTGTTCGCACTCACCTTCATCACCATAATC
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	AAACTATAGCTAGCAAGCTAGCCACACGACTCA
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	ACAGGAGAAAGACATGAGGTTATTACCAGTACATAC
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	TCACGTGGTCTTACCATCCAACAAGCCATTGGTTCTGG
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	AAAATACATCCTCGAAGCAGCAATCGAGGTAGC
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	GGTATCTTTGGTGCTGTATCCTCTACCACTGT
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	TAACTCCGCTGCTTCCCTGATTGCTGCTGCTAT
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	ACTTGGCTCATGCAGCCAACAACTACTCCCT
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	ATCATCCGGCACAAGGGGCGTGTGTATGCTCC
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	TATCAAGGTTCGTTGTCTCAATTGATTCTGCTGT
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	ATCACTGACTGTCGTGTCACTAAAGTGCTGGACGT
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	GTTTGTATCTCTGCCATTCGGGCTTCCCCTTGATAC
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	TTCCTTCAATGGCGTGAAAGCCAAGGAAGTGC
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	GTACCAGAACATCCATTCCTTACTCTTGGCTCCC
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	TTTACCGTATGGTCTGCCATTGGATACCATGACCA
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC

>NZ_CP047963|1|1|58641-60361|CRT
CCGCGAAGAACCTTATTAGCAGGGCGAACTTCTGAC	AGATATGTATGAAGCATTGTTGGCGGGTCTTTTGGAC
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	TATGAGGGATTGGTAGCGGCGGCTAGAAAAAAT
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	AATAGGTAACCCCTATGCGAATACTCAACACATA
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	GAATTGTTTAGCCTCAAGAGTCAACTTGGGGCTCT
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	AAAGCAATCCTTCAGTCCATCTGATGCATAACC
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	CGTCGAGAAATCTCTCGACGAACCTGAGGAGCCTAAG
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	TGATATATTCGACTCATTGGATTTGTACATATGGATA
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	ACTGGGTTACTGGAACCCTCGTGGAATCATTACTGC
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	AGTAGAGGAGCATTGCCTCACTCTGCTGACAAT
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	CACTGTTCGCACTCACCTTCATCACCATAATC
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	AAACTATAGCTAGCAAGCTAGCCACACGACTCA
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	ACAGGAGAAAGACATGAGGTTATTACCAGTACATAC
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	TCACGTGGTCTTACCATCCAACAAGCCATTGGTTCTGG
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	AAAATACATCCTCGAAGCAGCAATCGAGGTAGC
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	GGTATCTTTGGTGCTGTATCCTCTACCACTGT
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	TAACTCCGCTGCTTCCCTGATTGCTGCTGCTAT
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	ACTTGGCTCATGCAGCCAACAACTACTCCCT
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	ATCATCCGGCACAAGGGGCGTGTGTATGCTCC
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	TATCAAGGTTCGTTGTCTCAATTGATTCTGCTGT
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	ATCACTGACTGTCGTGTCACTAAAGTGCTGGACGT
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	GTTTGTATCTCTGCCATTCGGGCTTCCCCTTGATAC
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	TTCCTTCAATGGCGTGAAAGCCAAGGAAGTGC
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	GTACCAGAACATCCATTCCTTACTCTTGGCTCCC
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	TTTACCGTATGGTCTGCCATTGGATACCATGACCA
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC

>NZ_CP047963|1|1|58714-60361|PILER-CR
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	TATGAGGGATTGGTAGCGGCGGCTAGAAAAAAT
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	AATAGGTAACCCCTATGCGAATACTCAACACATA
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	GAATTGTTTAGCCTCAAGAGTCAACTTGGGGCTCT
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	AAAGCAATCCTTCAGTCCATCTGATGCATAACC
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	CGTCGAGAAATCTCTCGACGAACCTGAGGAGCCTAAG
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	TGATATATTCGACTCATTGGATTTGTACATATGGATA
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	ACTGGGTTACTGGAACCCTCGTGGAATCATTACTGC
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	AGTAGAGGAGCATTGCCTCACTCTGCTGACAAT
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	CACTGTTCGCACTCACCTTCATCACCATAATC
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	AAACTATAGCTAGCAAGCTAGCCACACGACTCA
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	ACAGGAGAAAGACATGAGGTTATTACCAGTACATAC
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	TCACGTGGTCTTACCATCCAACAAGCCATTGGTTCTGG
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	AAAATACATCCTCGAAGCAGCAATCGAGGTAGC
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	GGTATCTTTGGTGCTGTATCCTCTACCACTGT
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	TAACTCCGCTGCTTCCCTGATTGCTGCTGCTAT
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	ACTTGGCTCATGCAGCCAACAACTACTCCCT
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	ATCATCCGGCACAAGGGGCGTGTGTATGCTCC
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	TATCAAGGTTCGTTGTCTCAATTGATTCTGCTGT
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	ATCACTGACTGTCGTGTCACTAAAGTGCTGGACGT
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	GTTTGTATCTCTGCCATTCGGGCTTCCCCTTGATAC
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	TTCCTTCAATGGCGTGAAAGCCAAGGAAGTGC
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	GTACCAGAACATCCATTCCTTACTCTTGGCTCCC
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC	TTTACCGTATGGTCTGCCATTGGATACCATGACCA
GTCTTAATCCCTTTATTAGCAGGGCGAACTTCTGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047963.1\|WP_161508004.1\|49334_49823_+\|single-stranded-DNA-binding-protein	unknown	unknown	gnl\|CDD\|236362
NZ_CP047963.1\|WP_161507914.1\|63089_64082_+\|CRISPR-associated-endonuclease-Cas1	cas1	pfam01867_cas1_CAS-I:CAS-II:CAS-III	gnl\|CDD\|376633
NZ_CP047963.1\|WP_161507906.1\|49890_50706_-\|HDOD-domain-containing-protein	unknown	unknown	gnl\|CDD\|377859
NZ_CP047963.1\|WP_161507918.1\|66775_68758_+\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cd09679_cas10_CAS-III	gnl\|CDD\|187810
NZ_CP047963.1\|WP_161507917.1\|65603_66779_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr1	cmr1gr7	COG1367_cmr1gr7_CAS-III-B	gnl\|CDD\|377130
NZ_CP047963.1\|WP_161507913.1\|62728_63016_+\|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|187856
NZ_CP047963.1\|WP_161507916.1\|64348_65380_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226990
NZ_CP047963.1\|WP_161507919.1\|68751_69888_+\|hypothetical-protein	cmr3gr5	cd09748_cmr3gr5_CAS-III-B	gnl\|CDD\|187879
NZ_CP047963.1\|WP_161508002.1\|45386_46580_+\|ISL3-like-element-ISAeme19-family-transposase	unknown	unknown	gnl\|CDD\|376574
NZ_CP047963.1\|WP_161507911.1\|61966_62227_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047963.1\|WP_161507908.1\|53516_54467_+\|IS1595-like-element-ISAeca5-family-transposase	unknown	unknown	gnl\|CDD\|372298
NZ_CP047963.1\|WP_161507915.1\|64053_64329_+\|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|187856
NZ_CP047963.1\|WP_161507909.1\|54862_56416_+\|IS21-family-transposase	unknown	unknown	gnl\|CDD\|226950
NZ_CP047963.1\|WP_161507819.1\|57325_58540_+\|IS256-family-transposase	unknown	unknown	gnl\|CDD\|225865
NZ_CP047963.1\|WP_161508003.1\|47381_47825_+\|translesion-error-prone-DNA-polymerase-V-autoproteolytic-subunit	unknown	unknown	gnl\|CDD\|182350
NZ_CP047963.1\|WP_161507907.1\|51069_53301_-\|hypothetical-protein	DinG	COG1199_DinG_CAS-IV-A	gnl\|CDD\|236966
NZ_CP047963.1\|WP_161507905.1\|47805_49065_+\|translesion-error-prone-DNA-polymerase-V-subunit-UmuC	unknown	unknown	gnl\|CDD\|179607
NZ_CP047963.1\|WP_161507912.1\|62371_62632_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047963.1\|WP_161507910.1\|56438_57194_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|366760
NZ_CP047963.1\|WP_041205384.1\|60712_61810_+\|ISAs1-like-element-ISAeme2-family-transposase	unknown	unknown	gnl\|CDD\|379382

Protein	Function_ID	Function_description	E-value
NZ_CP047963.1\|WP_161508004.1\|49334_49823_+\|single-stranded-DNA-binding-protein	gnl\|CDD\|236362	PRK09010, PRK09010, single-stranded DNA-binding protein; Provisional.	8.21395e-65
NZ_CP047963.1\|WP_161507914.1\|63089_64082_+\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	3.90397e-80
NZ_CP047963.1\|WP_161507906.1\|49890_50706_-\|HDOD-domain-containing-protein	gnl\|CDD\|377859	pfam07514, TraI_2, Putative helicase. Some members of this family have been annotated as helicases.	2.85178e-08
NZ_CP047963.1\|WP_161507918.1\|66775_68758_+\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	gnl\|CDD\|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	3.56524e-43
NZ_CP047963.1\|WP_161507917.1\|65603_66779_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr1	gnl\|CDD\|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	1.67579e-10
NZ_CP047963.1\|WP_161507915.1\|64053_64329_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	6.61253e-15
NZ_CP047963.1\|WP_161507916.1\|64348_65380_+\|hypothetical-protein	gnl\|CDD\|226990	COG4643, COG4643, Uncharacterized protein conserved in bacteria [Function unknown].	1.37852e-06
NZ_CP047963.1\|WP_161507919.1\|68751_69888_+\|hypothetical-protein	gnl\|CDD\|187879	cd09748, Cmr3_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	4.22911e-56
NZ_CP047963.1\|WP_161508002.1\|45386_46580_+\|ISL3-like-element-ISAeme19-family-transposase	gnl\|CDD\|376574	pfam01610, DDE_Tnp_ISL3, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS1165.	4.35909e-82
NZ_CP047963.1\|WP_161507913.1\|62728_63016_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	5.56943e-06
NZ_CP047963.1\|WP_161507908.1\|53516_54467_+\|IS1595-like-element-ISAeca5-family-transposase	gnl\|CDD\|372298	pfam12762, DDE_Tnp_IS1595, ISXO2-like transposase domain. This domain probably functions as an integrase that is found in a wide variety of transposases, including ISXO2.	2.19139e-32
NZ_CP047963.1\|WP_161507909.1\|54862_56416_+\|IS21-family-transposase	gnl\|CDD\|226950	COG4584, COG4584, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.2708e-30
NZ_CP047963.1\|WP_161507819.1\|57325_58540_+\|IS256-family-transposase	gnl\|CDD\|225865	COG3328, COG3328, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.20923e-126
NZ_CP047963.1\|WP_161508003.1\|47381_47825_+\|translesion-error-prone-DNA-polymerase-V-autoproteolytic-subunit	gnl\|CDD\|182350	PRK10276, PRK10276, translesion error-prone DNA polymerase V autoproteolytic subunit.	3.42258e-51
NZ_CP047963.1\|WP_161507907.1\|51069_53301_-\|hypothetical-protein	gnl\|CDD\|236966	PRK11747, dinG, ATP-dependent DNA helicase DinG; Provisional.	2.24866e-144
NZ_CP047963.1\|WP_161507905.1\|47805_49065_+\|translesion-error-prone-DNA-polymerase-V-subunit-UmuC	gnl\|CDD\|179607	PRK03609, umuC, translesion error-prone DNA polymerase V subunit UmuC.	0
NZ_CP047963.1\|WP_161507910.1\|56438_57194_+\|ATP-binding-protein	gnl\|CDD\|366760	pfam01695, IstB_IS21, IstB-like ATP binding protein. This protein contains an ATP/GTP binding P-loop motif. It is found associated with IS21 family insertion sequences. The function of this protein is unknown, but it may perform a transposase function.	1.34094e-49
NZ_CP047963.1\|WP_041205384.1\|60712_61810_+\|ISAs1-like-element-ISAeme2-family-transposase	gnl\|CDD\|379382	pfam13808, DDE_Tnp_1_assoc, DDE_Tnp_1-associated. This domain is frequently found N-terminal to the transposase, IS family DDE_Tnp_1, pfam01609 and its relatives.	7.06729e-27

>NZ_CP047963.1|WP_161507819.1|57325_58540_+|IS256-family-transposase
MDQDKLKALAAELAKDIKSEKDLGTLTQQLIKLTVETALNAEMDEHLGYEKHAPQGRGTGNNRNGYSIKRLKGQHGEVTIQAPRDRNASFEPQFVRKGQSRLTQMDDQILALYAKGLSTRDIVDAFKEMYDADISAGLVSKVTERVIEQVHEWQNRPLDPLYPIVYLDCIVLKIRANQRVINKSLYLALGINMEGHKELLGLWLAETEGAKFWLSVLTELKNRGLEDILIACVDGLKGFPDAIAVEYPQTKVQLCIVHMVRNSLRYVSWKDYKAVTADLKQIYHSATEREAQQALAAFGERWDSQYPQIARSWQGNWDNLITLFDYPPAIRKVIYTTNAIESLNSVLRKATKQRKLFPTDESALKVAYLAIQQASKKWTMPIQNWKLALNRFIIEFGDRLNGHL
>NZ_CP047963.1|WP_161507910.1|56438_57194_+|ATP-binding-protein
MQLHLDEQLSRLHLSGMKQALNQQQAQSMLYLDMGFEERLQLLLSHELVQREQRKTNRLEKQARFRLAGQVEQLDYRAGRGVSKAQIRQLLEGHWLSHQQNLLLTGAAGCGKSYLACALGRYFIRQGVGVRYYRLKTLLEEMRLAQADGSYTKLLERVSNIGVLILDDWGMEMLDASERSNLLEIIDTRYGNVSTIVASQLPVEKWYGMIGEATFAEAILDRLIHRAVRVTLTGESMRKQGANLTDADQAE
>NZ_CP047963.1|WP_161507909.1|54862_56416_+|IS21-family-transposase
MSAKRIAMRKIREVLRLRLEADLSVRQISICTKVSVGSIQKLLKSAQALGLTWPLPTELDDGRLAALFYPQADTTISARHVVPDWPSVHQELKRKGVSKQLLWEEYTQRYPNSCYSYSQFCDRYKSWCQLQKRSMRQIHKAGEKLFIDYCGQTMPIVDPHTGEILYRAQIFVAVLGASNYTFAEATRSQQLDDWVMSHKRAFEFFGGVPQLVVPDCLKSAVSVARNTDPDLNPTYQMLAAHFGTAIMPARPRKPKDKSKAEVGVQIVTRWILAVLRHETFHSLAQLNQRMGELLTRLNQKSFQKLPGCRASLFAELDAPALKPLPDYPYHYTKVVPVLVGKDYHVDLEKHYYSVPYALQGKRLEAHLAEHTVTLYHAGKIVAEHQRSHHKGQHSSLREHMPAHHQALLEWSPERLLGWAASIGPYTTHWVDGFIRQAEHSTQAVRPCLALLGQSKTYGKERLEAACLRGHLTGANRLHNIRSMLKHGLEEQQLIANERQDPLQDIRHDNVHGEHYFH
>NZ_CP047963.1|WP_161507908.1|53516_54467_+|IS1595-like-element-ISAeca5-family-transposase
MAKSKVQFQKGYSLFDFFKDYGTEAQCENALLAWRFPNGFICPECANKTCCRLKSRPRVLQCNNCRHQMSLTGNTIFANTKLPLTKWFLAMQLLSQTKTGLSAMELKRQLDVKYDTAWMLKHKLLQAMKESDDKQPISGIIQLDDVYWGGERRGGKRGRGAAGKTPFVAAVALNKEGHPIKMRMTVVDGFKTNVITDWAKRHLASGSAVISDGLACFKAVKEANCEHLGVVTGGNLDLLDHPAFNWVNTMIGNVKNSLRGSCHKLGAKHLPRHLAEYCFRFNHRFDLKSMFVELGHAVVASPPMPYRLLKLAEGHG
>NZ_CP047963.1|WP_161507907.1|51069_53301_-|hypothetical-protein
MPGFTRPSTAAVANNAKTLQSALADKAELYQALAAHFSGFRVRPGQQQLSDAVTEGLFSRQLIACEAGTGVGKTMGYLLGAAPFLLDGSKRLLISTNTIALQNQLIQKDLPLFAAAVMPSIKIALAKSGKHYLCPHRVLSLLNRARKGDEVDQTELDLDTQGQKARHPQRPKIDPNLLIQVEEIWHQFDEGTFDGDLDTLGLGGEHQVNPFLSRIDNQCAGKQRCEQGDRCPFYEARDKLKRANVIVANHAFVTTCLLNDVTLFGDLDSLMVVIDEAHHFHDVLRNAMCNRFELDQIQEKLNVIANLLKDHRTLQNKGKLDYYDKQTLEAAYPALTLLEQAGQRLDHDMGQLGTFLSQNFAVLRGELRDRYDNPDQWLLGFEANEPVLARLFEQAMQASQTVLNRLTGYESRVQQLLNRLAEQLQSTNKKRSVEMLNSCEDLAIDITNIQKTLARFVEHDQYHCRADRIAAGHVRWITRTNNGTSIELASNPLYVANTFEQQLVSQVAGVVMVSATLSALGDMSFFAERLGISSQRGHRLLRVQSSFDYSKVSISAPFYNGDPNHASHSSKVAAYLCDHTLQRHRAVLLLFSSQRQLEEVYQALPHAVRQRVLCQRQLSKDALIKQHCQRIETGAISILFGLDGLAEGVDLPGHYLTCVIISKLPFSALNEPLLQHEQNVIEANGRNSFSELMLPLCSQKLIQSCGRLIRSEEDYGEIVLLDSRVNTKQYARRLLKALPMYKQ
>NZ_CP047963.1|WP_161507906.1|49890_50706_-|HDOD-domain-containing-protein
MEQWQLWTPGDTQLVVVSHSEMAHIEPSGQLVRWRLAAQPSAPVGLPTQGIAGMAGEAARQLWLFHLEQARSAAHGQMIEQLWQFYAGLPSGGVRQFVQGLLFDKPFIAAFYRGKASHHHHHDYEGGLLEHSVEVALTARMLCQQYQLDSRTADVAFLGGLLHDVGKLYLYYNNSSGEGICSSHEALNFMKLEPYLEPLMAREPRVFEALTACLSASVGKQQIQYMPETIVKMADRLSAEVYHWRRVFVGLPDFYWFHKSDEDARIYKRLG
>NZ_CP047963.1|WP_161508004.1|49334_49823_+|single-stranded-DNA-binding-protein
MATRGINKVMLIGHLGQEPEVRQMAQGGAVTTISLATSESWRDRQTDQQQERTEWHRVVFIGKIGEIAGQYLKKGSQVYVEGKLQTRKWQDQNGQDRYTTEVLVDSFNGVMQMLGGRNHQDGHPVSATEHSRITVPVDRKTPAPVTPPPPITDWDMNMDDPF
>NZ_CP047963.1|WP_161507905.1|47805_49065_+|translesion-error-prone-DNA-polymerase-V-subunit-UmuC
MAIALVDVNNFYASCERLFRPELRGRPLVVLSNNDGCVVSRSYEAKAMGIKMGVPYFQIREPFEAHGGVAFSSNYALYGDMSSRVMSTLETMAPELEVYSIDEAFLALSASFAGDLTAYGQRIRQRVQQWTGLTVGVGIGPTKTLAKLANYAAKKWPATGGVVDLHDELRRARLMAITPVEEVWGIGRRLTVKLQRQAIHTVADLVASDAKRLRAQFGVVVERIVQELRGLPCAELAVEPAAKQQILSSRSFGERITECAAMTQALAGFMARAAEKLRAEGMCCQRVHLFVRTSPFDERAPYYSEQAGGRLVCPTDDTRLLLQQVSVLLAQIWRDGHRYQKAGVMLSEFTPKGQQQADLFAPPSRQSDALMAVLDQIKAKGLGNVGFASQGTGSPEWMMRQAHLSPCYTTRWEDLPVAR
>NZ_CP047963.1|WP_161508003.1|47381_47825_+|translesion-error-prone-DNA-polymerase-V-autoproteolytic-subunit
MNLLTPDLSATEVAMPLFLQRASCGFPSPASDYLEGSLDLNRHCISHPAATFYLRAEGESMTGVGIFPGDLLVVDKSLTARHGDVVIALLDGGFTVKILQLIPRPALLPANPAFAPLAVDAEQGFELFGVVTHVIGNLRQRDGHCAG
>NZ_CP047963.1|WP_161508002.1|45386_46580_+|ISL3-like-element-ISAeme19-family-transposase
MDIASFWPGYTVIAQALSANHHTLFTLEPRADLLPRCRRCLQPTPLIHDQRIRRVRERDLFDRQVWLQLPVRRVDCLRCGRVSEHIDWLPSGSRLTRRMQCWIEALVQYLPIRHVSQLTGVGWHTIKEIDKRRLQTSVGTIELGEVRRLVMDEFALHKGHRYATVIMDAERTRVLWVGHGNSRAAIRPFFEQLGERCQQIEAVAMDMNTAFDLEVKQHCPQAEVVYDLFHVVARYGREVVDRVRVEQANALKSDKPARKVVKSARWLLLRNRAKLSEKQDVKLQELLAANQPLAMVYVLKEALKGIWYAPSVWEGWRRWRSWMRQVKESGLAPLQRFGRNLSKYMRGILASANYPMHTSVLEGVNNKIKVIKRMAYGFRDSEYFFLKIKAAFPGKPR
>NZ_CP047963.1|WP_041205384.1|60712_61810_+|ISAs1-like-element-ISAeme2-family-transposase
MTLIEHLTLVEETRSDINRKHDLVDVMFLVISAIISGAEGWRDIETYGNSKADWLRQYRPFANGIPRRHTIARILRCIVIDTLLEALLCWVNEQRTHQGKPIIAFDGKVLRGSFRGNAKDALQLVTAYDTENGLVLSQKATPNKKGEIETVKEMLDILELKGAVVTLDALHCQRETLQKISEKKAHVVVQVKKNQPKLYQAVQSQFQALFDAQKEKIVVEHKESGHGRQEERYVFQLKAKLPPELAEKWPTIRSIIAVERHRSANGKGTVDTSYYVSSLSPKHKLLGHYIRQHWRIENSQHYILDMVFNEDASRIAMEDAVENMALFRRFVLNIVKQSDCGAPSQRNKLKKASWDDNYRAQLFFG
>NZ_CP047963.1|WP_161507911.1|61966_62227_+|hypothetical-protein
MSVTTFNAATNVWHAKPLNRTGDLSSWQRRMQQACPQPVRGQVVYLDSTHFDRGEQRNITQRIGYLCTGFKPNGEPLWQRGMVQEI
>NZ_CP047963.1|WP_161507912.1|62371_62632_+|hypothetical-protein
MSVTTFNAATNVWHAKPLNRTGDLSSWQRRMQQACPQPARGQVVYLDSTHFDRGEQRSVSLRIGYLCIGFKPNGEPLWQRGMVQEI
>NZ_CP047963.1|WP_161507913.1|62728_63016_+|CRISPR-associated-endonuclease-Cas2
MFAIKRQLFVCCYDISDDKARKSVHRVVRSFVCGGQKSAYECFLSPSEAALLLAMTQGSLADGDNLVLQPISTARDIVTLGCASKPVNLGFCYLG
>NZ_CP047963.1|WP_161507914.1|63089_64082_+|CRISPR-associated-endonuclease-Cas1
METVFIDRRSSVVTIDRGRLSVRGADHHTSVPLRQMQALVICCDCQLSAAMLRSLSEHGVSLICLNHRNIDASLVSVPQSHGNVQRRIRQYQWLQDAQLMGRLATLIVRRKIALQRRTVVESLAVRPDCRFALFKGQAQLTDRLSDLRELSTGSNNEHDLIPTLLGIEGAAARIYFSAWQSVFPESWQFHRRTRRPPTDPVNALLSLGYTLLYFDAMRACYGAGLDPLIGILHQPSYGRASLACDLVELLRHRVDRWVWHMVRNQVLRPDHFVTEPQGACLLNKTGRQLFFEQYMLLAPQWRASLRRYSGALSNWLERGTDHGRQISDRL
>NZ_CP047963.1|WP_161507915.1|64053_64329_+|CRISPR-associated-endonuclease-Cas2
MAAKYLIAYDICHPRRLKRIHSLLLGYGIALQYSVFYAELAPAQLTQLIAQLADQIAPLHDKISVYALHEFDLTQWGRVNALMFNQAVLVL
>NZ_CP047963.1|WP_161507916.1|64348_65380_+|hypothetical-protein
MNLQPALDPWLILSAYADEFIALAQETGIDGARLLQQLPAPRQLLTGRQVPVCDKKYRNTCRVLFHLNDAREGGQWPLFQFHTFKHGGITRVFNGLRLWRSGLRCEPLATTRQLGHAKAVVQPDDNWRQQKVLNLAAAFFGAKPLQLDHPWLQTRLAHLANPLLLARLDARQQKDGSILLPLGHPQHGRVGFHLISPSANHDEKRHYIQTSGWLTGASITIEALPSASHAPTAICEGVATGLSVALFWPGNVVIALSANNLAAVRATLNEPVCFIADNDQWKPAVGNVGISSALQAAKEGDRVIWPRFAQYLHTRQPTDFNDLLLLAGKDETLRQLLALRDIP
>NZ_CP047963.1|WP_161507917.1|65603_66779_+|type-III-B-CRISPR-module-RAMP-protein-Cmr1
MIHTLTAELVISAPLITAGHSPLAKNDLIRPSAIKGALRFWWRAIQWQSIRRCHPCDNDALTALHQAESRLFGSAAGNSGHQAKVLLRLDAQQRLDNEAFAKGKDLAKIYPGAVYLLGQGQHQRNSGTQCAGLQATGPVKLKLCWRADTLDQAEQESVIKAVQALGLLGSLGARARKGFGSLSLQTLTLDRQSLPVPANTNELSNWFAGLSRDAVTELPPFTAISTASRCWVLGLKPARDPLALLNEYGLQMMQYRLSDKSALPGGQPGRGLFKSDTRSLRGVIDDGRPGKAPQRAVFGLPNNVFFVDNKQTVEVNPGKHERRASPLFAHLHRFPSGEQVLLATLVPARFLPDGEGLSIKHKGKRFALPFTPDWSVIEGFIKQCGGEELTR
>NZ_CP047963.1|WP_161507918.1|66775_68758_+|type-III-B-CRISPR-associated-protein-Cas10/Cmr2
MNQSHFHFTLGPVQAFVAQARRTRDFWAGSFLLSWLSSVAIKSVEAQQGEIAFPKPQPDYMAWLTGQGEGEAPKQGTIPNRFKALSAQIGHDFDPALVCASVQQAWQGLAELIWQGDIAPLAAQLGDVRLAATREIWDRQVKGFWEINWVISQDATAGSLLDRRKNWRSHLSPIEPGVKCMLMEGWQELSGLATPNRQGLSMFWETVRHGPAPELMVDIREGEVLCALAFIKRRFARYFDQLQLAMPGEWTLHGWTLPSSVPSLAHIAAGRWLEKLVTQAERTGNRDLLESFLLDLESARLDAANEKEASLPGITALAKAVSLDNVATLDGSLWFATQLSQKKDESLRLRQMHLAEHALQSLNRLQKILAIGTPHPFYAVLLMDGDSLGSQMSDPAKQAGISAALNEFTESAAQIVERHNGFLVYAGGDDVLALLGVSDAMACAAELRQSYADCFAQQNRQHQSHIVSTLSGAINIGHIKWPLRALLFDAHHLLDDIAKEMTGRDALAIRVWKHDKPHLCWSQPWEVLLGEQGNRVEWLLGHFAQGVTSNGFLFKLQTLITSLRLDQPHDFSEKSMRDLLWAEYCQSLGRQPKGHELDKRWLEELVTLSTPHVRSLENNTATLTPQHLLTPDAALLLRFLHEAYLAAGHLSVQSGLEQTC
>NZ_CP047963.1|WP_161507919.1|68751_69888_+|hypothetical-protein
MLTLAFHPVDTWFFRESRPMDSQGGTSLGNQFPPAPATLMGALRTRIGDMLGADWQNIGSLPSWWGDADQWGDLKLEGPWLRLGKEDFVPCPAHLLRQNDPASGYVMLMPGDMVHCDLGQVRLPALPNGTPPGVKPLDDHWLPRSALSPLLTGQLPGHKTPAVNTSALLADEYRLGIAIDHSKRAVVDGQLYQTRHLRPRQSLAVMVSLHGLPAEQEQALIRDLATQPLLRLGGEGRMAEVEVVERPTPVGQGTPPKKAKLLAVTQAPMAIVPEQWPLPGFIKQKRDDLDCWQGELGGYPLTLIAMATGKVRRQGGWDLTRHQPRPVHNVLPAGTVFFFDDAPLPRELCTLMLEQAGQQTPLTLGWWQDNQFLTRSDR

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Crispr_ID: NZ_CP047963_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047963_2

134386-134493

TypeV

Consensus_repeat	Method
CCTCCGCCTATCTTGTCCGAAGGA	CRISPRCasFinder

1 spacers

cas14j

The CRISPR arrays of NZ_CP047963_2

>merge|NZ_CP047963|2|134386-134493|CRISPRCasFinder
CCTCCGCCTATCTTGTCCGAAGGATTGGGATCCTGTCTGCACAACAACCCTTGTCAGACCAAGTATGCACGTTACTACCACGTTCCTTCGCCTATCTTGTCCGAAGGA

>NZ_CP047963|2|2|134386-134493|CRISPRCasFinder
CCTCCGCCTATCTTGTCCGAAGGA	TTGGGATCCTGTCTGCACAACAACCCTTGTCAGACCAAGTATGCACGTTACTACCACGTT
CCTTCGCCTATCTTGTCCGAAGGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047963.1\|WP_161507954.1\|131327_131861_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238431
NZ_CP047963.1\|WP_161507948.1\|125959_126493_-\|disulfide-bond-formation-protein-DsbB	unknown	unknown	gnl\|CDD\|234979
NZ_CP047963.1\|WP_041206016.1\|132984_134253_+\|IS4-like-element-ISAeme4-family-transposase	unknown	unknown	gnl\|CDD\|376573
NZ_CP047963.1\|WP_161507958.1\|136123_139177_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377859
NZ_CP047963.1\|WP_114523075.1\|144896_145211_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047963.1\|WP_161507951.1\|127845_128187_-\|carboxymuconolactone-decarboxylase-family-protein	unknown	unknown	gnl\|CDD\|223672
NZ_CP047963.1\|WP_161507949.1\|126508_127369_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293799
NZ_CP047963.1\|WP_161507955.1\|131835_132156_-\|DUF134-domain-containing-protein	unknown	unknown	gnl\|CDD\|224261
NZ_CP047963.1\|WP_161507959.1\|140182_140692_+\|cold-shock-domain-containing-protein	unknown	unknown	gnl\|CDD\|239905
NZ_CP047963.1\|WP_114523085.1\|142411_142696_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|225495
NZ_CP047963.1\|WP_161507947.1\|125599_125923_-\|rhodanese-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|182356
NZ_CP047963.1\|WP_161508005.1\|139431_140034_+\|cold-shock-domain-containing-protein	unknown	unknown	gnl\|CDD\|239905
NZ_CP047963.1\|WP_161507952.1\|128216_129926_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|163244
NZ_CP047963.1\|WP_161507953.1\|129961_130945_-\|C4-dicarboxylate-ABC-transporter	unknown	unknown	gnl\|CDD\|187763
NZ_CP047963.1\|WP_114523084.1\|142697_143030_-\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	unknown	unknown	gnl\|CDD\|368831
NZ_CP047963.1\|WP_161507956.1\|134780_135404_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047963.1\|WP_161507957.1\|135448_136063_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047963.1\|WP_041205447.1\|140688_141855_-\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	cas14j	-	gnl\|CDD\|223747
NZ_CP047963.1\|WP_161507960.1\|145680_145824_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047963.1\|WP_161507950.1\|127358_127796_-\|PaaI-family-thioesterase	unknown	unknown	gnl\|CDD\|239527

Protein	Function_ID	Function_description	E-value
NZ_CP047963.1\|WP_161507954.1\|131327_131861_-\|hypothetical-protein	gnl\|CDD\|238431	cd00851, MTH1175, This uncharacterized conserved protein belongs to a family of iron-molybdenum cluster-binding proteins that includes NifX, NifB, and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of the dinitrogenase enzyme. This domain is a predicted small-molecule-binding domain (SMBD) with an alpha/beta fold that is present either as a stand-alone domain (e.g. NifX and NifY) or fused to another conserved domain (e.g. NifB) however, its function is still undetermined.The SCOP database suggests that this domain is most similar to structures within the ribonuclease H superfamily. This conserved domain is represented in two of the three major divisions of life (bacteria and archaea).	3.6685e-13
NZ_CP047963.1\|WP_161507948.1\|125959_126493_-\|disulfide-bond-formation-protein-DsbB	gnl\|CDD\|234979	PRK01749, PRK01749, disulfide bond formation protein DsbB.	2.49938e-81
NZ_CP047963.1\|WP_041206016.1\|132984_134253_+\|IS4-like-element-ISAeme4-family-transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	2.18919e-12
NZ_CP047963.1\|WP_161507958.1\|136123_139177_+\|hypothetical-protein	gnl\|CDD\|377859	pfam07514, TraI_2, Putative helicase. Some members of this family have been annotated as helicases.	6.89981e-45
NZ_CP047963.1\|WP_161507951.1\|127845_128187_-\|carboxymuconolactone-decarboxylase-family-protein	gnl\|CDD\|223672	COG0599, COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown].	9.55097e-21
NZ_CP047963.1\|WP_161507949.1\|126508_127369_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293799	cd07713, DHPS-like_MBL-fold, Methanocaldococcus jannaschii dihydropteroate synthase, Thermoanaerobacter tengcongensis Tflp, and related proteins; MBL-fold metallo hydrolase domain. This subgroup includes Methanocaldococcus jannaschii 7,8-dihydropterin-6-methyl-4-(beta-D-ribofuranosyl)-aminobenzene-5'-phosphate synthase (EC 2.5.1.15), a folate biosynthetic enzyme also known as dihydropteroate synthase and 7,8 dihydropteroate synthase. Thermoanaerobacter tengcongensis Tflp is a ferredoxin-like member. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	5.45019e-85
NZ_CP047963.1\|WP_161507955.1\|131835_132156_-\|DUF134-domain-containing-protein	gnl\|CDD\|224261	COG1342, COG1342, Predicted DNA-binding proteins [General function prediction only].	1.8404e-35
NZ_CP047963.1\|WP_114523085.1\|142411_142696_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|225495	COG2944, COG2944, Predicted transcriptional regulator [Transcription].	1.59913e-13
NZ_CP047963.1\|WP_161507947.1\|125599_125923_-\|rhodanese-like-domain-containing-protein	gnl\|CDD\|182356	PRK10287, PRK10287, thiosulfate:cyanide sulfurtransferase; Provisional.	3.47402e-19
NZ_CP047963.1\|WP_161507952.1\|128216_129926_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|163244	TIGR03385, Coenzyme_A_disulfide_reductase, CoA-disulfide reductase. Members of this protein family are CoA-disulfide reductase (EC 1.8.1.14), as characterized in Staphylococcus aureus, Pyrococcus horikoshii, and Borrelia burgdorferi, and inferred in several other species on the basis of high levels of CoA and an absence of glutathione as a protective thiol. [Cellular processes, Detoxification].	1.22912e-156
NZ_CP047963.1\|WP_161507953.1\|129961_130945_-\|C4-dicarboxylate-ABC-transporter	gnl\|CDD\|187763	cd09323, TDT_SLAC1_like, Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes SLAC1 (Slow Anion Channel-Associated 1). SLAC1 (Slow Anion Channel-Associated 1) is a plasma membrane protein, preferentially expressed in guard cells, which encodes a distant homolog of fungal and bacterial dicarboxylate/malic acid transport proteins. It is essential for stomatal closure in response to carbon dioxide, abscisic acid, ozone, light/dark transitions, humidity change, calcium ions, hydrogen peroxide and nitric oxide. In the Arabidopsis genome, SLAC1 is part of a gene family with five members and encodes a membrane protein that has ten putative transmembrane domains flanked by large N- and C-terminal domains. Mutations in SLAC1 impair slow (S-type) anion channel currents that are activated by cytosolic calcium ions and abscisic acid, but do not affect rapid (R-type) anion channel currents or calcium ion channel function.	2.17403e-118
NZ_CP047963.1\|WP_114523084.1\|142697_143030_-\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	gnl\|CDD\|368831	pfam06296, RelE, RelE toxin of RelE / RelB toxin-antitoxin system. RelE is a family of Gram-negative bacterial antitoxins of the RelE/RelB toxin-antitoxin system. Its cognate antitoxin is family RelB, pfam04221.	8.997e-07
NZ_CP047963.1\|WP_161508005.1\|139431_140034_+\|cold-shock-domain-containing-protein	gnl\|CDD\|239905	cd04458, CSP_CDS, Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein. CSP expression is up-regulated by an abrupt drop in growth temperature. CSP's are also expressed under normal condition at lower level. The function of cold-shock proteins is not fully understood. They preferentially bind poly-pyrimidine region of single-stranded RNA and DNA. CSP's are thought to bind mRNA and regulate ribosomal translation, mRNA degradation, and the rate of transcription termination. The human Y-box protein, which contains a CSD, regulates transcription and translation of genes that contain the Y-box sequence in their promoters. This specific ssDNA-binding properties of CSD are required for the binding of Y-box protein to the promoter's Y-box sequence, thereby regulating transcription.	1.45451e-18
NZ_CP047963.1\|WP_161507959.1\|140182_140692_+\|cold-shock-domain-containing-protein	gnl\|CDD\|239905	cd04458, CSP_CDS, Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein. CSP expression is up-regulated by an abrupt drop in growth temperature. CSP's are also expressed under normal condition at lower level. The function of cold-shock proteins is not fully understood. They preferentially bind poly-pyrimidine region of single-stranded RNA and DNA. CSP's are thought to bind mRNA and regulate ribosomal translation, mRNA degradation, and the rate of transcription termination. The human Y-box protein, which contains a CSD, regulates transcription and translation of genes that contain the Y-box sequence in their promoters. This specific ssDNA-binding properties of CSD are required for the binding of Y-box protein to the promoter's Y-box sequence, thereby regulating transcription.	6.81471e-11
NZ_CP047963.1\|WP_041205447.1\|140688_141855_-\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl\|CDD\|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.63676e-54
NZ_CP047963.1\|WP_161507950.1\|127358_127796_-\|PaaI-family-thioesterase	gnl\|CDD\|239527	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not been determined. Sequence similarity between PaaI, E. coli medium chain acyl-CoA thioesterase II, and human thioesterase III suggests they all belong to the same thioesterase superfamily. The conserved fold present in these thioesterases is referred to as an asymmetric hot dog fold, similar to those of 4-hydroxybenzoyl-CoA thioesterase (4HBT) and the beta-hydroxydecanoyl-ACP dehydratases (FabA/FabZ).	1.81617e-14

>NZ_CP047963.1|WP_041206016.1|132984_134253_+|IS4-like-element-ISAeme4-family-transposase
MTIIDANHYLEQLLSPAELDRIARDCQFCLRKRAITPAMLVTALLRALGCDQVDGIAGLHHHFNALQLVDAHQVSYKPFHNQLRKASFALFMKALVERAIALRIGQQMKTASLGAFKQVLLQDGTSFAVHKSLAEVFPGRFKTISPAAIECHMLMSLLEQSPVCMQVSADTASERQFLPEPERLNNSLLLADAGYIDMAYFAKLNEAGGFYLVRGSKSLNPKIIRAWRGDEREVPKLAGLSLKDAGRRHCRAEVLDMVVKSGKFEYRLIRRWFAEEKRFCIWMTNLPREAWPAERVMSLYRCRWQVELLFKEWKSHNRLKGFVTGQKAIAEGLVWASLLSLVMKRRVAQTLMGDGLSTLKAAKNSGTWWFPLLEAVAHRVLVEIRERLEWAAVYLAKNARRTKQRKSIQNRTLEGISNEVFS
>NZ_CP047963.1|WP_161507955.1|131835_132156_-|DUF134-domain-containing-protein
MARPKIPRNICGRPADSCFKPNARPMSQLEQVRLKDDEFEALRLVDLLGMQQQEAAIEMGVSRQTLANVLKAARFKVVDCLTQGKALMMHLEDEGDSKNDHCHSNE
>NZ_CP047963.1|WP_161507954.1|131327_131861_-|hypothetical-protein
MITAIPMNDDRVANHFTKANCLVFLDERGIEINRVDNPALAEGCAGKQKMVDLLAEQQVDRIVVRNIGEQMLGKLLARQFAVYQTNCGRRSAHELVDPIASGLLQLHQASQGRQSLNHEAKAKSGGCGCHHPEGEHSDACCHTANSPRQEMAPSQRNQMRRQDCGRHGQGRGRCCQS
>NZ_CP047963.1|WP_161507953.1|129961_130945_-|C4-dicarboxylate-ABC-transporter
MTLNIDSPESAPALPRIAYFPVSFFSMIMGLSGFTLAWKAAAGIFSSGTDIWIVFAYATSIAMIFVSIFYAIKIWHYPHAVLEEIHHPVRINFFPSFSISLLLLSVVWQQETIVSTYLWMVGTALQIAFTLYVMSSWIHHTHYTLSHANPSWFIPVVGNIIVPITGSQLGYIELSWFCFSIGIVFWLVLLTIIMYRLFFHEPLPARMTPMLFILLAPPSVGFISYTSMVGELDAFARIIYYIALFLSLLLAMNIFRFIKVPFFISSWAYSFPVAALTVATIKMAHLTSSLFFQTISVVLLCMLTGLLLWLVTRTVKAIFAAEFCRPE
>NZ_CP047963.1|WP_161507952.1|128216_129926_-|FAD-dependent-oxidoreductase
MTKIVIIGGVAGGASAAARARRVSEDAEIIILERGEFVSFANCGLPYHISGEIDSREALLLQTPESFKKRFNVDVRVLNEVTHIDPIKKIVTVKRIQTGEIYQESYDKLLLSPGASPVKPAIPGIANSHVYSLRNIPDMDKILVMLAAEKPKHATVVGGGFIGLEMVEALHRRGVAVTLLELSDQVMAPVDREMAAMLHQHMRDKGIDLRLKTGLAAISVADFCPAEPESTGVYDQPATHTHNLNLMLSSGDMLPTGMVILAIGVKPETTLASTAGLALGDLGGIKVNSAMQTSDPDIYAVGDVIETENFITGEAALVPLAGPANRQGRIAADNMLGRHEHYRRTQGTAICKVFDMAIGSTGLNEKTLKRLNMTYEKIYVHTASHASYYPGAHPVTLKLLFDPTDGQILGAQAAGLDGIDKRIDVLAVAQRARMTVQQLADLELTYAPPFGSARDVVNQAGMVASNVMNGDEAICHTEELLLGASDQVVLDVRNPPELEASGSFPNALNIPLDELRDRLYTLPVDKEILVACQVGLRGHVAYRMLVQNGFQARNLTGGYKTYQMVTDTL
>NZ_CP047963.1|WP_161507951.1|127845_128187_-|carboxymuconolactone-decarboxylase-family-protein
MAKNYTEINQEQRQFGSAYRKASPDTMNAFLALHKAAMREGELSVKHKELIATAISIAARCDGCIGAHVAAALKAGASKQELVETIDVAVLMGGGPAVIYGTQALAAVEELAN
>NZ_CP047963.1|WP_161507950.1|127358_127796_-|PaaI-family-thioesterase
MNSYQHAQRSHAHCMVCGLREHNSDSLGLVFSPQFDGTVSAPFVVSPKHQGYTGLLHGGMTSTLLDAAMTHCLFSQGIQALTAELTVRFMEPIRLGQTLMVCAKMLGQRRGIYQLEAWLMAGQQKVARASAKFIAPSPGSLAHGN
>NZ_CP047963.1|WP_161507949.1|126508_127369_-|MBL-fold-metallo-hydrolase
MAINVELTVLCDNHAQGELQAEHGLAFWMDAPELQLLFDTGSGQTLAQNAAQLQIPLDECQMVVLSHGHYDHTGGLRELWQQGVTCPVMAHPSVILPRYSRHPGKPVRRIGMPTDVVRQIWQLPTTMRLWNLDPQLLTPYWGTSGEIPRLDPLEDVGGPFFLDAEGFESDELPDDQALWFNTPKGLVIVLGCCHSGLINTITHLRQVTGILKVAGLIGGLHLLHADESRLAHTMSFLKRCQLDFLRLGHCTGDSVIERIQRELPEVDVQSLQVGARYVIEAQRIVT
>NZ_CP047963.1|WP_161507948.1|125959_126493_-|disulfide-bond-formation-protein-DsbB
MIAYLQGITQQRWSWVLLLVSALFLELCAMLFQHGLGLFPCVMCVYERIATMGLMAAALVALIDPKRALFRWLGILIWGYSAIRGLQLALKHVDYLLNPSPFNTCSVLPDFPSWLPLDTWAPWFFAAYADCAERQWSLLGWELPQWLVPIFALYLVIWLVIFIANLAQKGRFGTCGE
>NZ_CP047963.1|WP_161507947.1|125599_125923_-|rhodanese-like-domain-containing-protein
MLMRTLLLGAALLASLSVQAKEWLIDVRTAEEFSADHVAGATNIEFQQIVPQVSKLGIAKQEPIRLYCRSGRRAESARQALIHNGYENVINLGSISDAKIKWKSKKS
>NZ_CP047963.1|WP_161507956.1|134780_135404_+|hypothetical-protein
MVQDMPVGPVCNEIAEPLREALAKASATVAEFAQVIIDRYWQEFRRKNQDQRHLPEDRRQLGRYAPNMRRHKANNKIYFVWRNYQPTRKGTRKGRILGVDIKPAKGLHYTEKQFMAYARPWEFSLIVRTERQLAALRELQEGIHKHIVHLAKCERVFEWKQQLEIDKSAIPTTPKLTEINKGEVRKTIAEYEAELSRELEIKTLDNM
>NZ_CP047963.1|WP_161507957.1|135448_136063_+|hypothetical-protein
MELNTKSTMLNRHINSANHKKANTAFMRVGTLLVMTANDPVNQKKITDWLDYLLKQMTDNINSDQESIRVLWTGSAPKLDIVPVAGEAKHYFYINHPRLRLFINQFNRVDGLAYEVDQLWFAGLMSDERREMSYKKLLYPMNAITEHFNYVTNISRRSGGTYTPEEFLKLLSEQESMRTFIMHHFEGPEHVKYAGTVKKFAGCE
>NZ_CP047963.1|WP_161507958.1|136123_139177_+|hypothetical-protein
MQVDSAIFRLFAWCARTAKRFNKKGPPPRNELLQVVRTVSGDQIVPSGVYYSPMPIIGIQPLSIEDILRPHSGTINEIIQRSGLSTTHAKYNPTKLITDVIERVAEYIHLLPASEDYHHTETGGLLSHSLEVAKIALGEAYNIDLPSKTYPDLETIRRTRYFYAVFVAALLHDVGKVFSDIRVTCVDKNTVWAPHVEPLTTWALKNKVASYQVEYKRGRGRSHERAANYITMSVLSTEAREYLSSCKTDNLYMEIDEAISHYAEREEYISLALRRADSASTLKDIQGRHVKETGRREFSLATLFIRACQRLTADWTCNTKGAMLWLIGGDVFIAYTQAIEAIMEEIRSSGVSIPTDVNEIYNRLIEQHIIESLDKETRSVFWSPGHFTEDEARQIQEDLLINRINRPWLSLVKLKSVNYAYGSVVLPESQPGLMCLNKGGDMMLYRKGSLYQPVILSAEEMHKRRKELEEKAKAEAEATQAEKEKALQEAVKEALERERAAQAANGHADATGGGNPDQIPVSEYNYPLFDYEHEYLEESGALWDDYAAMNQSVYENTDANGPQSSQDSEDDDADTDAAGNESDAAESVSEAGKKKRARSRVKKRLAERADGSEQLPDDDELDADDETPPPPATSNGGMSRKQKLEAKRAAKSSSEPEVAVETPDTPVQEVAVNVQVAQPAVPQDDSPSPATPEQVVAEPTTPTPEPVQSPKPAQAPRKASGQDNQDRARQWLSWCSAQRNSGVLMYRTINDISYLRVGLLAKHLLKEVDEVIETLAQGKTIQATLETAASPDRCYVVMMPNEQGQQEECCQLSIRGQKIMAAVSEPKREEPDRREFVSVFERLQRGDEEEQVMAVVETESTGNAVLPDSPPAPSSVEDKDPAPTPVTQVQSNTPESEQESVVVQDNKPTPDDDDDFEEEDEDMDEEEINQSALSAALHPIGYRWREISDFAETMKRLRWGRGKDRDAMMETDEGFAIRSSYFRENGEHYFNFPLSELKEFRKKIDGKWYYVVPREQP
>NZ_CP047963.1|WP_161508005.1|139431_140034_+|cold-shock-domain-containing-protein
MRLKGKLVRWNGDKGFGFIRCEENHEEYFVHISAFPRDGVPPRIDESVSFEVGKGRDGRPRAESVHRGNGPAPVKVHQPHRAPSTPKSPRRPNPRSTRPRFTSLLMSVALLAGGYWAAKPLLSGQDTQPTAQMSQVNSSAVDEQQDDNLDVAASQFSCDGRTYCSEMGSYEEAKFFLDNCPNTKLDGNHDGEPCEWQFGH
>NZ_CP047963.1|WP_161507959.1|140182_140692_+|cold-shock-domain-containing-protein
MRTDGTVVVWYDDKGFGFVREAHTMREFFFHISAYCHDGQRPQLGDKVRFGVLQGHGDRSIAVGVWQHKVKPGDEHIPSGKDSDKLPFPHARDELRKWLRITPHRIVVATAALAGVLYIVQQTLVLPETFPNNAHAGTVLEAEAKEWSKNLFKAEGDCSPPQAARLPTS
>NZ_CP047963.1|WP_041205447.1|140688_141855_-|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MKRATKVRIYPTDEQAAFLNAQFGAVRFAYNKALHLQQHMFKRHGVSLKPKRDLKPLLAVAKKSRKYGWLKEYDSLALQQAVINLDKAFVNFFNPKLKARMPTFKSKRGRQSSYHPNGKVLADAIQLPKMTPIRAVIHRDIIGVVSSITVSRGPTGKYYASILCDDGCEAPAKSTFITDVTGCDMGLSHYLIQSNGKKTDNPRHLVNASRNLRRKQKALSRKKKGSANRGKARRQLAALHERVANARADFQHKLSRTMVDDSQAIIVETLKSANMMKNHKLARAIGDAGWHGFIMKLEYKAQAAGRHLIKLDQWFASSKLCSDCGHKMPDMPLHQRQWACPACGAEHDRDINAAMNIQQQGILELKAAGLVVSTHGGQRQSANSAVAA
>NZ_CP047963.1|WP_114523085.1|142411_142696_-|helix-turn-helix-domain-containing-protein
MSMFNELQASLEEAIAIKQGRSEASELTRYEVADVKAIRAALDLSQQEFAIGLGTSVDTVKSWETRRRNPTGLTAKVLALLQERPELFRELAAH
>NZ_CP047963.1|WP_114523084.1|142697_143030_-|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin
MSHAIEFIETSIFTKQIKALATDDELKSLQVELIADPEKGDLIQGTGGLRKVRMATGQQGKSGSARVIYFLAHAEKIYLVLAYSKSEKSSLTAAEKAILKKLTAQLKDED
>NZ_CP047963.1|WP_114523075.1|144896_145211_+|hypothetical-protein
MSFSALTLSFDVYLVVLACATGYAIYRGFKWVRDIQATQKHILARLKQQESASALKEYETAEALKRVQSQMELLAYLEQKRIERDLEQDETAFKSMRARRTSSR
>NZ_CP047963.1|WP_161507960.1|145680_145824_-|hypothetical-protein
MSSLGSASAKDRQGVKPAEEMSADTPAPGWPPAEQRPAINRREKNGK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP047963_1	1.1\|58677\|37\|NZ_CP047963\|CRISPRCasFinder,CRT	58677-58713	37	NZ_CP047963	Aeromonas media strain MC64 plasmid pMC64A, complete sequence	58677-58713	0	1.0
NZ_CP047963_1	1.2\|58750\|33\|NZ_CP047963\|CRISPRCasFinder,CRT,PILER-CR	58750-58782	33	NZ_CP047963	Aeromonas media strain MC64 plasmid pMC64A, complete sequence	58750-58782	0	1.0
NZ_CP047963_1	1.3\|58819\|34\|NZ_CP047963\|CRISPRCasFinder,CRT,PILER-CR	58819-58852	34	NZ_CP047963	Aeromonas media strain MC64 plasmid pMC64A, complete sequence	58819-58852	0	1.0
NZ_CP047963_1	1.4\|58889\|35\|NZ_CP047963\|CRISPRCasFinder,CRT,PILER-CR	58889-58923	35	NZ_CP047963	Aeromonas media strain MC64 plasmid pMC64A, complete sequence	58889-58923	0	1.0
NZ_CP047963_1	1.5\|58960\|33\|NZ_CP047963\|CRISPRCasFinder,CRT,PILER-CR	58960-58992	33	NZ_CP047963	Aeromonas media strain MC64 plasmid pMC64A, complete sequence	58960-58992	0	1.0
NZ_CP047963_1	1.6\|59029\|37\|NZ_CP047963\|CRISPRCasFinder,CRT,PILER-CR	59029-59065	37	NZ_CP047963	Aeromonas media strain MC64 plasmid pMC64A, complete sequence	59029-59065	0	1.0
NZ_CP047963_1	1.7\|59102\|37\|NZ_CP047963\|CRISPRCasFinder,CRT,PILER-CR	59102-59138	37	NZ_CP047963	Aeromonas media strain MC64 plasmid pMC64A, complete sequence	59102-59138	0	1.0
NZ_CP047963_1	1.8\|59175\|36\|NZ_CP047963\|CRISPRCasFinder,CRT,PILER-CR	59175-59210	36	NZ_CP047963	Aeromonas media strain MC64 plasmid pMC64A, complete sequence	59175-59210	0	1.0
NZ_CP047963_1	1.9\|59247\|33\|NZ_CP047963\|CRISPRCasFinder,CRT,PILER-CR	59247-59279	33	NZ_CP047963	Aeromonas media strain MC64 plasmid pMC64A, complete sequence	59247-59279	0	1.0
NZ_CP047963_1	1.10\|59316\|32\|NZ_CP047963\|CRISPRCasFinder,CRT,PILER-CR	59316-59347	32	NZ_CP047963	Aeromonas media strain MC64 plasmid pMC64A, complete sequence	59316-59347	0	1.0
NZ_CP047963_1	1.11\|59384\|33\|NZ_CP047963\|CRISPRCasFinder,CRT,PILER-CR	59384-59416	33	NZ_CP047963	Aeromonas media strain MC64 plasmid pMC64A, complete sequence	59384-59416	0	1.0
NZ_CP047963_1	1.12\|59453\|36\|NZ_CP047963\|CRISPRCasFinder,CRT,PILER-CR	59453-59488	36	NZ_CP047963	Aeromonas media strain MC64 plasmid pMC64A, complete sequence	59453-59488	0	1.0
NZ_CP047963_1	1.13\|59525\|38\|NZ_CP047963\|CRISPRCasFinder,CRT,PILER-CR	59525-59562	38	NZ_CP047963	Aeromonas media strain MC64 plasmid pMC64A, complete sequence	59525-59562	0	1.0
NZ_CP047963_1	1.14\|59599\|33\|NZ_CP047963\|CRISPRCasFinder,CRT,PILER-CR	59599-59631	33	NZ_CP047963	Aeromonas media strain MC64 plasmid pMC64A, complete sequence	59599-59631	0	1.0
NZ_CP047963_1	1.15\|59668\|32\|NZ_CP047963\|CRISPRCasFinder,CRT,PILER-CR	59668-59699	32	NZ_CP047963	Aeromonas media strain MC64 plasmid pMC64A, complete sequence	59668-59699	0	1.0
NZ_CP047963_1	1.16\|59736\|33\|NZ_CP047963\|CRISPRCasFinder,CRT,PILER-CR	59736-59768	33	NZ_CP047963	Aeromonas media strain MC64 plasmid pMC64A, complete sequence	59736-59768	0	1.0
NZ_CP047963_1	1.17\|59805\|31\|NZ_CP047963\|CRISPRCasFinder,CRT,PILER-CR	59805-59835	31	NZ_CP047963	Aeromonas media strain MC64 plasmid pMC64A, complete sequence	59805-59835	0	1.0
NZ_CP047963_1	1.18\|59872\|32\|NZ_CP047963\|CRISPRCasFinder,CRT,PILER-CR	59872-59903	32	NZ_CP047963	Aeromonas media strain MC64 plasmid pMC64A, complete sequence	59872-59903	0	1.0
NZ_CP047963_1	1.19\|59940\|34\|NZ_CP047963\|CRISPRCasFinder,CRT,PILER-CR	59940-59973	34	NZ_CP047963	Aeromonas media strain MC64 plasmid pMC64A, complete sequence	59940-59973	0	1.0
NZ_CP047963_1	1.20\|60010\|35\|NZ_CP047963\|CRISPRCasFinder,CRT,PILER-CR	60010-60044	35	NZ_CP047963	Aeromonas media strain MC64 plasmid pMC64A, complete sequence	60010-60044	0	1.0
NZ_CP047963_1	1.21\|60081\|36\|NZ_CP047963\|CRISPRCasFinder,CRT,PILER-CR	60081-60116	36	NZ_CP047963	Aeromonas media strain MC64 plasmid pMC64A, complete sequence	60081-60116	0	1.0
NZ_CP047963_1	1.22\|60153\|32\|NZ_CP047963\|CRISPRCasFinder,CRT,PILER-CR	60153-60184	32	NZ_CP047963	Aeromonas media strain MC64 plasmid pMC64A, complete sequence	60153-60184	0	1.0
NZ_CP047963_1	1.23\|60221\|34\|NZ_CP047963\|CRISPRCasFinder,CRT,PILER-CR	60221-60254	34	NZ_CP047963	Aeromonas media strain MC64 plasmid pMC64A, complete sequence	60221-60254	0	1.0
NZ_CP047963_1	1.24\|60291\|35\|NZ_CP047963\|CRISPRCasFinder,CRT,PILER-CR	60291-60325	35	NZ_CP047963	Aeromonas media strain MC64 plasmid pMC64A, complete sequence	60291-60325	0	1.0
NZ_CP047963_2	2.1\|134410\|60\|NZ_CP047963\|CRISPRCasFinder	134410-134469	60	NZ_CP047963	Aeromonas media strain MC64 plasmid pMC64A, complete sequence	134410-134469	0	1.0
NZ_CP047963_1	1.22\|60153\|32\|NZ_CP047963\|CRISPRCasFinder,CRT,PILER-CR	60153-60184	32	MT259468	Aeromonas phage PS, complete genome	37899-37930	1	0.969
NZ_CP047963_1	1.14\|59599\|33\|NZ_CP047963\|CRISPRCasFinder,CRT,PILER-CR	59599-59631	33	NZ_CP036351	Planctomycetes bacterium K2D plasmid pK2D_1, complete sequence	46696-46728	10	0.697
NZ_CP047963_1	1.23\|60221\|34\|NZ_CP047963\|CRISPRCasFinder,CRT,PILER-CR	60221-60254	34	MF285618	Serratia phage 2050HW, complete genome	254807-254840	10	0.706
NZ_CP047963_1	1.23\|60221\|34\|NZ_CP047963\|CRISPRCasFinder,CRT,PILER-CR	60221-60254	34	NC_048792	Serratia phage Moabite, complete genome	45126-45159	10	0.706
NZ_CP047963_1	1.14\|59599\|33\|NZ_CP047963\|CRISPRCasFinder,CRT,PILER-CR	59599-59631	33	NZ_CP012182	Pseudonocardia sp. EC080610-09 plasmid pBCI2-1, complete sequence	278712-278744	11	0.667
NZ_CP047963_1	1.14\|59599\|33\|NZ_CP047963\|CRISPRCasFinder,CRT,PILER-CR	59599-59631	33	NZ_CP012185	Pseudonocardia sp. EC080619-01 plasmid pBCI1-2, complete sequence	769847-769879	11	0.667

1. spacer 1.1|58677|37|NZ_CP047963|CRISPRCasFinder,CRT matches to NZ_CP047963 (Aeromonas media strain MC64 plasmid pMC64A, complete sequence) position: , mismatch: 0, identity: 1.0

agatatgtatgaagcattgttggcgggtcttttggac	CRISPR spacer
agatatgtatgaagcattgttggcgggtcttttggac	Protospacer
*************************************

2. spacer 1.2|58750|33|NZ_CP047963|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP047963 (Aeromonas media strain MC64 plasmid pMC64A, complete sequence) position: , mismatch: 0, identity: 1.0

tatgagggattggtagcggcggctagaaaaaat	CRISPR spacer
tatgagggattggtagcggcggctagaaaaaat	Protospacer
*********************************

3. spacer 1.3|58819|34|NZ_CP047963|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP047963 (Aeromonas media strain MC64 plasmid pMC64A, complete sequence) position: , mismatch: 0, identity: 1.0

aataggtaacccctatgcgaatactcaacacata	CRISPR spacer
aataggtaacccctatgcgaatactcaacacata	Protospacer
**********************************

4. spacer 1.4|58889|35|NZ_CP047963|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP047963 (Aeromonas media strain MC64 plasmid pMC64A, complete sequence) position: , mismatch: 0, identity: 1.0

gaattgtttagcctcaagagtcaacttggggctct	CRISPR spacer
gaattgtttagcctcaagagtcaacttggggctct	Protospacer
***********************************

5. spacer 1.5|58960|33|NZ_CP047963|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP047963 (Aeromonas media strain MC64 plasmid pMC64A, complete sequence) position: , mismatch: 0, identity: 1.0

aaagcaatccttcagtccatctgatgcataacc	CRISPR spacer
aaagcaatccttcagtccatctgatgcataacc	Protospacer
*********************************

6. spacer 1.6|59029|37|NZ_CP047963|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP047963 (Aeromonas media strain MC64 plasmid pMC64A, complete sequence) position: , mismatch: 0, identity: 1.0

cgtcgagaaatctctcgacgaacctgaggagcctaag	CRISPR spacer
cgtcgagaaatctctcgacgaacctgaggagcctaag	Protospacer
*************************************

7. spacer 1.7|59102|37|NZ_CP047963|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP047963 (Aeromonas media strain MC64 plasmid pMC64A, complete sequence) position: , mismatch: 0, identity: 1.0

tgatatattcgactcattggatttgtacatatggata	CRISPR spacer
tgatatattcgactcattggatttgtacatatggata	Protospacer
*************************************

8. spacer 1.8|59175|36|NZ_CP047963|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP047963 (Aeromonas media strain MC64 plasmid pMC64A, complete sequence) position: , mismatch: 0, identity: 1.0

actgggttactggaaccctcgtggaatcattactgc	CRISPR spacer
actgggttactggaaccctcgtggaatcattactgc	Protospacer
************************************

9. spacer 1.9|59247|33|NZ_CP047963|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP047963 (Aeromonas media strain MC64 plasmid pMC64A, complete sequence) position: , mismatch: 0, identity: 1.0

agtagaggagcattgcctcactctgctgacaat	CRISPR spacer
agtagaggagcattgcctcactctgctgacaat	Protospacer
*********************************

10. spacer 1.10|59316|32|NZ_CP047963|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP047963 (Aeromonas media strain MC64 plasmid pMC64A, complete sequence) position: , mismatch: 0, identity: 1.0

cactgttcgcactcaccttcatcaccataatc	CRISPR spacer
cactgttcgcactcaccttcatcaccataatc	Protospacer
********************************

11. spacer 1.11|59384|33|NZ_CP047963|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP047963 (Aeromonas media strain MC64 plasmid pMC64A, complete sequence) position: , mismatch: 0, identity: 1.0

aaactatagctagcaagctagccacacgactca	CRISPR spacer
aaactatagctagcaagctagccacacgactca	Protospacer
*********************************

12. spacer 1.12|59453|36|NZ_CP047963|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP047963 (Aeromonas media strain MC64 plasmid pMC64A, complete sequence) position: , mismatch: 0, identity: 1.0

acaggagaaagacatgaggttattaccagtacatac	CRISPR spacer
acaggagaaagacatgaggttattaccagtacatac	Protospacer
************************************

13. spacer 1.13|59525|38|NZ_CP047963|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP047963 (Aeromonas media strain MC64 plasmid pMC64A, complete sequence) position: , mismatch: 0, identity: 1.0

tcacgtggtcttaccatccaacaagccattggttctgg	CRISPR spacer
tcacgtggtcttaccatccaacaagccattggttctgg	Protospacer
**************************************

14. spacer 1.14|59599|33|NZ_CP047963|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP047963 (Aeromonas media strain MC64 plasmid pMC64A, complete sequence) position: , mismatch: 0, identity: 1.0

aaaatacatcctcgaagcagcaatcgaggtagc	CRISPR spacer
aaaatacatcctcgaagcagcaatcgaggtagc	Protospacer
*********************************

15. spacer 1.15|59668|32|NZ_CP047963|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP047963 (Aeromonas media strain MC64 plasmid pMC64A, complete sequence) position: , mismatch: 0, identity: 1.0

ggtatctttggtgctgtatcctctaccactgt	CRISPR spacer
ggtatctttggtgctgtatcctctaccactgt	Protospacer
********************************

16. spacer 1.16|59736|33|NZ_CP047963|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP047963 (Aeromonas media strain MC64 plasmid pMC64A, complete sequence) position: , mismatch: 0, identity: 1.0

taactccgctgcttccctgattgctgctgctat	CRISPR spacer
taactccgctgcttccctgattgctgctgctat	Protospacer
*********************************

17. spacer 1.17|59805|31|NZ_CP047963|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP047963 (Aeromonas media strain MC64 plasmid pMC64A, complete sequence) position: , mismatch: 0, identity: 1.0

acttggctcatgcagccaacaactactccct	CRISPR spacer
acttggctcatgcagccaacaactactccct	Protospacer
*******************************

18. spacer 1.18|59872|32|NZ_CP047963|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP047963 (Aeromonas media strain MC64 plasmid pMC64A, complete sequence) position: , mismatch: 0, identity: 1.0

atcatccggcacaaggggcgtgtgtatgctcc	CRISPR spacer
atcatccggcacaaggggcgtgtgtatgctcc	Protospacer
********************************

19. spacer 1.19|59940|34|NZ_CP047963|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP047963 (Aeromonas media strain MC64 plasmid pMC64A, complete sequence) position: , mismatch: 0, identity: 1.0

tatcaaggttcgttgtctcaattgattctgctgt	CRISPR spacer
tatcaaggttcgttgtctcaattgattctgctgt	Protospacer
**********************************

20. spacer 1.20|60010|35|NZ_CP047963|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP047963 (Aeromonas media strain MC64 plasmid pMC64A, complete sequence) position: , mismatch: 0, identity: 1.0

atcactgactgtcgtgtcactaaagtgctggacgt	CRISPR spacer
atcactgactgtcgtgtcactaaagtgctggacgt	Protospacer
***********************************

21. spacer 1.21|60081|36|NZ_CP047963|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP047963 (Aeromonas media strain MC64 plasmid pMC64A, complete sequence) position: , mismatch: 0, identity: 1.0

gtttgtatctctgccattcgggcttccccttgatac	CRISPR spacer
gtttgtatctctgccattcgggcttccccttgatac	Protospacer
************************************

22. spacer 1.22|60153|32|NZ_CP047963|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP047963 (Aeromonas media strain MC64 plasmid pMC64A, complete sequence) position: , mismatch: 0, identity: 1.0

ttccttcaatggcgtgaaagccaaggaagtgc	CRISPR spacer
ttccttcaatggcgtgaaagccaaggaagtgc	Protospacer
********************************

23. spacer 1.23|60221|34|NZ_CP047963|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP047963 (Aeromonas media strain MC64 plasmid pMC64A, complete sequence) position: , mismatch: 0, identity: 1.0

gtaccagaacatccattccttactcttggctccc	CRISPR spacer
gtaccagaacatccattccttactcttggctccc	Protospacer
**********************************

24. spacer 1.24|60291|35|NZ_CP047963|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP047963 (Aeromonas media strain MC64 plasmid pMC64A, complete sequence) position: , mismatch: 0, identity: 1.0

tttaccgtatggtctgccattggataccatgacca	CRISPR spacer
tttaccgtatggtctgccattggataccatgacca	Protospacer
***********************************

25. spacer 2.1|134410|60|NZ_CP047963|CRISPRCasFinder matches to NZ_CP047963 (Aeromonas media strain MC64 plasmid pMC64A, complete sequence) position: , mismatch: 0, identity: 1.0

ttgggatcctgtctgcacaacaacccttgtcagaccaagtatgcacgttactaccacgtt	CRISPR spacer
ttgggatcctgtctgcacaacaacccttgtcagaccaagtatgcacgttactaccacgtt	Protospacer
************************************************************

26. spacer 1.22|60153|32|NZ_CP047963|CRISPRCasFinder,CRT,PILER-CR matches to MT259468 (Aeromonas phage PS, complete genome) position: , mismatch: 1, identity: 0.969

ttccttcaatggcgtgaaagccaaggaagtgc	CRISPR spacer
ttccttcaatggcgtgaaagccaaggaagtac	Protospacer
******************************.*

27. spacer 1.14|59599|33|NZ_CP047963|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP036351 (Planctomycetes bacterium K2D plasmid pK2D_1, complete sequence) position: , mismatch: 10, identity: 0.697

aaaatacatcctcgaagcagcaatcgaggtagc	CRISPR spacer
tgagatcatccgcgaagcagcaatcgaagttcg	Protospacer
 .*.  ***** ***************.**

28. spacer 1.23|60221|34|NZ_CP047963|CRISPRCasFinder,CRT,PILER-CR matches to MF285618 (Serratia phage 2050HW, complete genome) position: , mismatch: 10, identity: 0.706

gtaccagaacatccattccttactcttggctccc	CRISPR spacer
attgctgaacagccgttccttactcttggcatag	Protospacer
.*  * ***** **.*************** .

29. spacer 1.23|60221|34|NZ_CP047963|CRISPRCasFinder,CRT,PILER-CR matches to NC_048792 (Serratia phage Moabite, complete genome) position: , mismatch: 10, identity: 0.706

gtaccagaacatccattccttactcttggctccc	CRISPR spacer
attgctgaacagccgttccttactcttggcatag	Protospacer
.*  * ***** **.*************** .

30. spacer 1.14|59599|33|NZ_CP047963|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012182 (Pseudonocardia sp. EC080610-09 plasmid pBCI2-1, complete sequence) position: , mismatch: 11, identity: 0.667

aaaatacatcctcgaagcagcaatcgaggtagc	CRISPR spacer
cctcgacatcctcaaggcagcaatcgaggcgcg	Protospacer
     ********.*.*************..

31. spacer 1.14|59599|33|NZ_CP047963|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012185 (Pseudonocardia sp. EC080619-01 plasmid pBCI1-2, complete sequence) position: , mismatch: 11, identity: 0.667

aaaatacatcctcgaagcagcaatcgaggtagc	CRISPR spacer
cctcgacatcctcaaggcagcaatcgaggcgcg	Protospacer
     ********.*.*************..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

5535 : 61810

Enterobacteria_phage(12.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013213985.1\|5535_6516_-\|transposase	IS481-like element ISKpn27 family transposase	A8RHK4	Spiroplasma_virus	2.9e-10	27.4
WP_001217881.1\|6638_7196_-	recombinase family protein	Q1MVP4	Enterobacteria_phage	2.0e-93	98.4
WP_161507889.1\|7358_7559_+	DUF4158 domain-containing protein	Q1MVP5	Enterobacteria_phage	2.8e-21	100.0
WP_041204923.1\|7529_8672_-\|transposase	IS4-like element ISAs18 family transposase	NA	NA	NA	NA
WP_021141311.1\|9727_10864_-\|transposase	ISAs1-like element ISAs12 family transposase	NA	NA	NA	NA
WP_161507890.1\|13560_14745_-	Fic family protein	D7RWK9	Brochothrix_phage	1.5e-05	25.2
WP_099368947.1\|14979_16067_-\|transposase	IS3-like element ISKpn10 family transposase	S5WIU1	Leptospira_phage	3.8e-43	36.0
WP_161507891.1\|16388_17426_+	hypothetical protein	NA	NA	NA	NA
WP_161507892.1\|17524_18697_+	nuclease	A0A2R2ZH57	Clostridioides_phage	5.2e-22	27.5
WP_021141233.1\|19485_19890_-\|transposase	IS200/IS605-like element ISAs26 family transposase	I4AZM1	Saccharomonospora_phage	8.5e-33	54.4
WP_021141234.1\|19947_21174_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	O80301	Enterobacteria_phage	7.7e-154	78.6
WP_161507893.1\|21493_22393_-	DNA/RNA non-specific endonuclease	A0A1V0SA52	Catovirus	2.7e-07	30.8
WP_114523319.1\|22472_24263_+	ATP-dependent helicase	E3T5J8	Cafeteria_roenbergensis_virus	3.7e-19	22.9
WP_114523111.1\|25413_26502_+	hypothetical protein	NA	NA	NA	NA
WP_161507894.1\|26613_27669_+	AAA domain-containing protein	A0A1Y0SVK5	Sinorhizobium_phage	2.1e-06	28.5
WP_161507895.1\|27931_28894_+	DUF3150 domain-containing protein	NA	NA	NA	NA
WP_161507896.1\|28955_30878_+	VWA domain-containing protein	NA	NA	NA	NA
WP_114523107.1\|31084_32155_+	hypothetical protein	NA	NA	NA	NA
WP_161507897.1\|32168_32684_+	hypothetical protein	NA	NA	NA	NA
WP_161507898.1\|32785_32932_+	hypothetical protein	NA	NA	NA	NA
WP_161507899.1\|33269_33626_+	hypothetical protein	NA	NA	NA	NA
WP_161507900.1\|33742_34849_+	DNA cytosine methyltransferase	NA	NA	NA	NA
WP_161507901.1\|34989_35133_+	hypothetical protein	NA	NA	NA	NA
WP_041204891.1\|35124_36261_-\|transposase	ISAs1-like element ISAeme1 family transposase	NA	NA	NA	NA
WP_041206863.1\|36713_37853_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A077SLN2	Escherichia_phage	7.2e-146	68.7
WP_041205574.1\|37910_38336_+\|transposase	IS200/IS605-like element ISAeme8 family transposase	A0A1S5RHE3	Helicobacter_phage	4.9e-23	46.9
WP_114523103.1\|38692_38962_+	hypothetical protein	NA	NA	NA	NA
WP_012564931.1\|39230_40178_-\|transposase	IS30-like element ISAeca1 family transposase	Q9MBM9	Staphylococcus_prophage	1.0e-44	36.9
WP_001809438.1\|40404_41436_-\|transposase	IS630-like element ISAhy2 family transposase	NA	NA	NA	NA
WP_161508001.1\|41526_42540_+\|transposase	IS481 family transposase	A0A0M3LS26	Mannheimia_phage	4.0e-71	42.5
WP_161507902.1\|42714_43266_-	hypothetical protein	A0A1S6UB21	Serratia_phage	2.1e-05	50.9
WP_161507903.1\|43292_44150_-	ADP-ribosylglycohydrolase family protein	A0A1S6UB21	Serratia_phage	1.3e-54	45.6
WP_161507904.1\|44429_45380_+\|transposase	IS1595-like element ISAeca5 family transposase	NA	NA	NA	NA
WP_161508002.1\|45386_46580_+\|transposase	ISL3-like element ISAeme19 family transposase	A9YX10	Burkholderia_phage	1.3e-102	53.2
WP_161508003.1\|47381_47825_+	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	5.5e-33	52.0
WP_161507905.1\|47805_49065_+	translesion error-prone DNA polymerase V subunit UmuC	F1C5A5	Cronobacter_phage	3.1e-121	53.7
WP_161508004.1\|49334_49823_+	single-stranded DNA-binding protein	A0A2I7RML0	Vibrio_phage	1.4e-45	66.1
WP_161507906.1\|49890_50706_-	HDOD domain-containing protein	NA	NA	NA	NA
WP_161507907.1\|51069_53301_-	hypothetical protein	A0A127AW80	Bacillus_phage	9.2e-28	22.3
WP_161507908.1\|53516_54467_+\|transposase	IS1595-like element ISAeca5 family transposase	NA	NA	NA	NA
WP_161507909.1\|54862_56416_+\|transposase	IS21 family transposase	K4I413	Acidithiobacillus_phage	9.9e-122	45.8
WP_161507910.1\|56438_57194_+	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	1.8e-52	45.0
WP_161507819.1\|57325_58540_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	8.7e-49	49.5
WP_041205384.1\|60712_61810_+\|transposase	ISAs1-like element ISAeme2 family transposase	NA	NA	NA	NA

DBSCAN-SWA_2

76514 : 134253

Escherichia_phage(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_052814785.1\|76514_78125_-\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	2.8e-58	32.7
WP_042012890.1\|78174_78540_-	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_042012893.1\|78539_78848_-	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_161507926.1\|80921_81176_+	hypothetical protein	NA	NA	NA	NA
WP_161507927.1\|81375_82602_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	O80301	Enterobacteria_phage	7.7e-154	78.9
WP_011191341.1\|83759_85034_-\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA
WP_114523099.1\|85683_86043_+	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	8.1e-19	38.4
WP_161507928.1\|86039_87311_+	translesion error-prone DNA polymerase V subunit UmuC	F1C5A5	Cronobacter_phage	7.1e-102	45.8
WP_161507929.1\|87422_87887_+	hypothetical protein	NA	NA	NA	NA
WP_161507930.1\|87971_88376_-	hypothetical protein	NA	NA	NA	NA
WP_052814785.1\|88522_90133_-\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	2.8e-58	32.7
WP_042012890.1\|90182_90548_-	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_042012893.1\|90547_90856_-	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_143237393.1\|90993_92082_+\|transposase	IS4-like element ISAs18 family transposase	NA	NA	NA	NA
WP_161507931.1\|92033_94334_-	conjugal transfer protein TraG	NA	NA	NA	NA
WP_011191341.1\|94433_95708_-\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA
WP_161507932.1\|95772_96270_-	conjugal transfer protein TraG	NA	NA	NA	NA
WP_114523095.1\|96281_97616_-	hypothetical protein	NA	NA	NA	NA
WP_161507933.1\|97615_98647_-	conjugal transfer protein TraF	NA	NA	NA	NA
WP_161507934.1\|98932_99388_-	hypothetical protein	NA	NA	NA	NA
WP_119197661.1\|99466_100693_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	O80301	Enterobacteria_phage	7.7e-154	78.9
WP_161507935.1\|100750_101155_+\|transposase	IS200/IS605 family transposase	I4AZM1	Saccharomonospora_phage	1.8e-30	52.0
WP_161507936.1\|101180_101468_-	hypothetical protein	NA	NA	NA	NA
WP_114523092.1\|101767_102811_+	hypothetical protein	NA	NA	NA	NA
WP_114523091.1\|102803_103175_+	hypothetical protein	NA	NA	NA	NA
WP_161507814.1\|104274_105546_-\|transposase	transposase	NA	NA	NA	NA
WP_161507937.1\|107605_108253_-	hypothetical protein	NA	NA	NA	NA
WP_041204923.1\|108315_109458_-\|transposase	IS4-like element ISAs18 family transposase	NA	NA	NA	NA
WP_161507938.1\|109544_109832_-	hypothetical protein	NA	NA	NA	NA
WP_161507939.1\|109992_110904_+	WYL domain-containing protein	NA	NA	NA	NA
WP_161507940.1\|110900_113756_+	DEAD/DEAH box helicase	A0A2H4J643	uncultured_Caudovirales_phage	1.2e-184	40.2
WP_161507941.1\|113752_114880_+	AAA family ATPase	A0A077SLJ9	Escherichia_phage	1.0e-14	24.2
WP_161507942.1\|114876_115521_+	DUF4276 family protein	NA	NA	NA	NA
WP_161507943.1\|115538_116042_+	site-specific DNA-methyltransferase	A0A0M7Q8J6	Escherichia_phage	7.5e-47	60.8
WP_161507944.1\|116152_117088_+	hypothetical protein	A0A0K1LNZ9	Escherichia_phage	2.7e-34	61.3
WP_004576012.1\|117350_118769_-\|transposase	IS66-like element ISAs21 family transposase	NA	NA	NA	NA
WP_052815201.1\|119069_120323_-\|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	8.3e-95	45.6
WP_161507945.1\|121765_124618_+	DEAD/DEAH box helicase family protein	NA	NA	NA	NA
WP_161507946.1\|124996_125473_-	DNA starvation/stationary phase protection protein	NA	NA	NA	NA
WP_161507947.1\|125599_125923_-	rhodanese-like domain-containing protein	NA	NA	NA	NA
WP_161507948.1\|125959_126493_-	disulfide bond formation protein DsbB	NA	NA	NA	NA
WP_161507949.1\|126508_127369_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_161507950.1\|127358_127796_-	PaaI family thioesterase	NA	NA	NA	NA
WP_161507951.1\|127845_128187_-	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_161507952.1\|128216_129926_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_161507953.1\|129961_130945_-	C4-dicarboxylate ABC transporter	NA	NA	NA	NA
WP_161507954.1\|131327_131861_-	hypothetical protein	NA	NA	NA	NA
WP_161507955.1\|131835_132156_-	DUF134 domain-containing protein	NA	NA	NA	NA
WP_041206016.1\|132984_134253_+\|transposase	IS4-like element ISAeme4 family transposase	NA	NA	NA	NA

DBSCAN-SWA_3

140688 : 189583

Enterobacteria_phage(30.43%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041205447.1\|140688_141855_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A077SLN2	Escherichia_phage	7.4e-146	67.9
WP_114523085.1\|142411_142696_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_114523084.1\|142697_143030_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_114523075.1\|144896_145211_+	hypothetical protein	NA	NA	NA	NA
WP_161507960.1\|145680_145824_-	hypothetical protein	NA	NA	NA	NA
WP_161507961.1\|147023_147368_-	hypothetical protein	NA	NA	NA	NA
WP_021141233.1\|147447_147852_-\|transposase	IS200/IS605-like element ISAs26 family transposase	I4AZM1	Saccharomonospora_phage	8.5e-33	54.4
WP_041206018.1\|147909_149136_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	O80301	Enterobacteria_phage	1.3e-153	78.6
WP_084865641.1\|149298_150501_-\|transposase	ISL3-like element ISAeme19 family transposase	A9YX10	Burkholderia_phage	1.4e-102	53.2
WP_114522800.1\|150646_150937_-	hypothetical protein	NA	NA	NA	NA
WP_147273898.1\|151043_151469_-	hypothetical protein	NA	NA	NA	NA
WP_161507962.1\|151868_152870_-	ParB N-terminal domain-containing protein	O64340	Escherichia_phage	6.6e-10	28.4
WP_114522803.1\|152869_154102_-	ParA family protein	Q1MVJ3	Enterobacteria_phage	6.2e-34	30.7
WP_114522804.1\|154403_154742_+	hypothetical protein	NA	NA	NA	NA
WP_161507963.1\|155124_155367_-	hypothetical protein	NA	NA	NA	NA
WP_041206863.1\|155453_156593_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A077SLN2	Escherichia_phage	7.2e-146	68.7
WP_041205574.1\|156650_157076_+\|transposase	IS200/IS605-like element ISAeme8 family transposase	A0A1S5RHE3	Helicobacter_phage	4.9e-23	46.9
WP_161507964.1\|157072_157609_-	hypothetical protein	NA	NA	NA	NA
WP_147273899.1\|157868_159821_-	hypothetical protein	NA	NA	NA	NA
WP_161507927.1\|160622_161849_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	O80301	Enterobacteria_phage	7.7e-154	78.9
WP_147273900.1\|162411_162930_-	hypothetical protein	NA	NA	NA	NA
WP_041205447.1\|163107_164274_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A077SLN2	Escherichia_phage	7.4e-146	67.9
WP_114522808.1\|164819_165161_+	hypothetical protein	NA	NA	NA	NA
WP_041205447.1\|165259_166426_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A077SLN2	Escherichia_phage	7.4e-146	67.9
WP_114522809.1\|166666_167305_+	hypothetical protein	NA	NA	NA	NA
WP_114522810.1\|167316_167934_+	single-stranded DNA-binding protein	A0A2I7RHA9	Vibrio_phage	1.2e-43	67.2
WP_161507927.1\|168167_169394_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	O80301	Enterobacteria_phage	7.7e-154	78.9
WP_114522813.1\|170861_171218_+	hypothetical protein	NA	NA	NA	NA
WP_161507927.1\|171317_172544_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	O80301	Enterobacteria_phage	7.7e-154	78.9
WP_021141233.1\|172601_173006_+\|transposase	IS200/IS605-like element ISAs26 family transposase	I4AZM1	Saccharomonospora_phage	8.5e-33	54.4
WP_114522814.1\|173093_173654_+	DUF2726 domain-containing protein	NA	NA	NA	NA
WP_161507965.1\|174157_175477_-	hypothetical protein	V5YTC9	Pseudomonas_phage	2.4e-20	26.5
WP_147273901.1\|175553_176267_-	hypothetical protein	NA	NA	NA	NA
WP_161507966.1\|176675_177401_-	thioredoxin fold domain-containing protein	NA	NA	NA	NA
WP_114522818.1\|177397_177919_-	hypothetical protein	NA	NA	NA	NA
WP_114522819.1\|178078_178321_-	hypothetical protein	NA	NA	NA	NA
WP_114522820.1\|178484_178805_+	hypothetical protein	NA	NA	NA	NA
WP_114522821.1\|178789_179515_+	hypothetical protein	NA	NA	NA	NA
WP_130627553.1\|179727_180378_-	Qnr family pentapeptide repeat protein	NA	NA	NA	NA
WP_130627552.1\|180514_180946_-	transcriptional regulator	A0A0C4UQZ9	Shigella_phage	1.0e-23	43.3
WP_084865641.1\|181136_182339_+\|transposase	ISL3-like element ISAeme19 family transposase	A9YX10	Burkholderia_phage	1.4e-102	53.2
WP_114522822.1\|182468_182684_+	hypothetical protein	NA	NA	NA	NA
WP_114522781.1\|182956_183361_-\|transposase	IS200/IS605 family transposase	I4AZM1	Saccharomonospora_phage	3.2e-32	53.6
WP_119197661.1\|183418_184645_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	O80301	Enterobacteria_phage	7.7e-154	78.9
WP_161507967.1\|184689_184956_+	hypothetical protein	NA	NA	NA	NA
WP_161507968.1\|185123_185543_+	hypothetical protein	NA	NA	NA	NA
WP_161507969.1\|185539_186619_-	hypothetical protein	NA	NA	NA	NA
WP_161507970.1\|186801_187869_+	DUF4942 domain-containing protein	A0A2I7RNS1	Vibrio_phage	6.4e-11	35.3
WP_021141233.1\|187894_188299_-\|transposase	IS200/IS605-like element ISAs26 family transposase	I4AZM1	Saccharomonospora_phage	8.5e-33	54.4
WP_021141234.1\|188356_189583_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	O80301	Enterobacteria_phage	7.7e-154	78.6

DBSCAN-SWA_4

208246 : 267977

Escherichia_phage(11.76%)

transposase,integrase

attL 222400:222421|attR 256360:256381

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_021141311.1\|208246_209383_-\|transposase	ISAs1-like element ISAs12 family transposase	NA	NA	NA	NA
WP_107979024.1\|209660_210140_+	hypothetical protein	NA	NA	NA	NA
WP_161507980.1\|210102_211740_-	EAL domain-containing protein	NA	NA	NA	NA
WP_101618122.1\|211928_213203_+	glucose-1-phosphate adenylyltransferase	NA	NA	NA	NA
WP_101618123.1\|213261_215262_-	hypothetical protein	NA	NA	NA	NA
WP_102948393.1\|215886_217091_-\|transposase	IS3 family transposase	Q9ZXG3	Shigella_phage	4.5e-114	70.1
WP_021141311.1\|217952_219089_-\|transposase	ISAs1-like element ISAs12 family transposase	NA	NA	NA	NA
WP_058671242.1\|219531_220338_-	DUF4225 domain-containing protein	NA	NA	NA	NA
WP_005342491.1\|220426_221377_-\|transposase	IS1595-like element ISKpn3 family transposase	NA	NA	NA	NA
222400:222421	attL	NA	NA	NA	NA
WP_161508006.1\|222676_223579_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_019706001.1\|223678_224626_+\|transposase	IS30-like element ISAs2 family transposase	Q9MBM9	Staphylococcus_prophage	1.4e-41	35.7
WP_000184001.1\|224996_226202_+	chromate efflux transporter	NA	NA	NA	NA
WP_000130000.1\|226212_226518_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_001389365.1\|226744_227509_+\|transposase	IS6-like element IS6100 family transposase	A0A077SL39	Escherichia_phage	4.3e-86	65.7
WP_001137892.1\|228001_228586_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_000004159.1\|228585_229824_-	MFS transporter	NA	NA	NA	NA
WP_000219391.1\|229820_230726_-	Mph(A) family macrolide 2'-phosphotransferase	NA	NA	NA	NA
WP_001067855.1\|230847_231552_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_113736295.1\|231816_233368_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_000557454.1\|233453_234314_+	aminoglycoside N-acetyltransferase AAC(3)-IId	NA	NA	NA	NA
WP_000587837.1\|234326_234869_+	AAA family ATPase	NA	NA	NA	NA
WP_000951934.1\|235350_235542_-	hypothetical protein	NA	NA	NA	NA
WP_000248278.1\|235565_235793_+	hypothetical protein	NA	NA	NA	NA
WP_000080861.1\|235843_236980_+	DUF3883 domain-containing protein	NA	NA	NA	NA
WP_014342212.1\|236946_237096_-	hypothetical protein	NA	NA	NA	NA
WP_000971921.1\|237094_238465_+\|transposase	IS1182-like element ISCfr1 family transposase	NA	NA	NA	NA
WP_014342213.1\|238606_238732_-	hypothetical protein	NA	NA	NA	NA
WP_000027057.1\|239285_240146_+	class A broad-spectrum beta-lactamase TEM-1	Q1MVP3	Enterobacteria_phage	4.6e-161	100.0
WP_161507981.1\|240308_241355_+	hypothetical protein	NA	NA	NA	NA
WP_041206683.1\|242354_243896_+\|transposase	IS21 family transposase	K4I413	Acidithiobacillus_phage	3.2e-128	47.2
WP_161506736.1\|243910_244666_+	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	6.8e-60	51.9
WP_021141311.1\|246364_247501_+\|transposase	ISAs1-like element ISAs12 family transposase	NA	NA	NA	NA
WP_041206016.1\|247748_249017_+\|transposase	IS4-like element ISAeme4 family transposase	NA	NA	NA	NA
WP_114523317.1\|249687_250095_+	H-NS histone family protein	NA	NA	NA	NA
WP_161507982.1\|250427_250589_+	hypothetical protein	NA	NA	NA	NA
WP_114523314.1\|250829_251132_+	hypothetical protein	NA	NA	NA	NA
WP_161507983.1\|251185_252247_+\|integrase	tyrosine-type recombinase/integrase	A0A2I7QY74	Vibrio_phage	1.2e-38	32.9
WP_161507927.1\|252790_254017_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	O80301	Enterobacteria_phage	7.7e-154	78.9
WP_042650430.1\|254412_255666_-\|transposase	IS256-like element ISAeme25 family transposase	A0A2P1JQX9	Mycobacterium_phage	7.0e-94	47.2
WP_161507984.1\|255973_256396_+	sel1 repeat family protein	NA	NA	NA	NA
256360:256381	attR	NA	NA	NA	NA
WP_161507985.1\|257817_258024_+	helix-turn-helix domain-containing protein	A0A1B1IUF9	uncultured_Mediterranean_phage	1.3e-13	50.0
WP_161507986.1\|258046_259684_+	ATP-dependent DNA helicase	A0A1B3AYT3	Gordonia_phage	7.7e-16	26.7
WP_161507987.1\|259899_261459_+	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	1.0e-102	42.1
WP_161507988.1\|261455_262496_+	DUF1016 domain-containing protein	Q9JMP5	Wolbachia_phage	1.6e-112	58.4
WP_161507989.1\|262492_263683_+	restriction endonuclease subunit S	A0A240FAT6	Liberibacter_phage	8.0e-39	50.9
WP_161507990.1\|263850_264882_+	cell filamentation protein Fic	Q9JMN3	Wolbachia_phage	7.6e-86	50.2
WP_161507991.1\|264878_267977_+	type I restriction endonuclease subunit R	A0A220A398	Liberibacter_phage	2.2e-24	23.5

Anti-CRISPR protein detection

Acr_ID: NZ_CP047963.1|WP_161507891.1|16388_17426_+|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_CP047963.1|WP_161507891.1|16388_17426_+|hypothetical-protein

16388_17426_+

345 aa aa

5535-61810

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP047962_6	Orphan	6.1\|3595865\|30\|NZ_CP047962\|CRISPRCasFinder	3595865-3595894	30	40232-40261	0

1. spacer 6.1|3595865|30|NZ_CP047962|CRISPRCasFinder matches to NZ_CP047963 position: 40232-40261, mismatch: 0

accgcctctctcctatgcaccatgggcatt	CRISPR spacer
accgcctctctcctatgcaccatgggcatt	Protospacer
******************************

3. NZ_CP047962

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP047962_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047962_1

25993-26131

Orphan

Consensus_repeat	Method
GCGCTGGTGGGATGAGGCGTGGGAACGCAGTTGTTGAAGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP047962_1

>merge|NZ_CP047962|1|25993-26131|CRISPRCasFinder
GCGCTGGTGGGATGAGGCGTGGGAACGCAGTTGTTGAAGCGGGTCTGATAGCGACAGGCCAACTTCAAACGTGCTTATCGCATTGTCACAAACTCTTCCGCGCTGGTGGGATGAGGAGTGGGAACGCAGTTGTTGAAGC

>NZ_CP047962|1|1|25993-26131|CRISPRCasFinder
GCGCTGGTGGGATGAGGCGTGGGAACGCAGTTGTTGAAGC	GGGTCTGATAGCGACAGGCCAACTTCAAACGTGCTTATCGCATTGTCACAAACTCTTCC
GCGCTGGTGGGATGAGGAGTGGGAACGCAGTTGTTGAAGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047962.1\|WP_161507809.1\|35366_35840_+\|ricin-type-beta-trefoil-lectin-domain-protein	unknown	unknown	gnl\|CDD\|214672
NZ_CP047962.1\|WP_139750694.1\|22974_23838_+\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP047962.1\|WP_161506701.1\|37931_38678_-\|tRNA-(guanosine(18)-2'-O)-methyltransferase-TrmH	unknown	unknown	gnl\|CDD\|236837
NZ_CP047962.1\|WP_161506695.1\|22340_22784_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224647
NZ_CP047962.1\|WP_161506699.1\|27591_29550_-\|PAS-domain-S-box-protein	unknown	unknown	gnl\|CDD\|226654
NZ_CP047962.1\|WP_043132721.1\|12824_13952_+\|multidrug-effflux-MFS-transporter	unknown	unknown	gnl\|CDD\|340878
NZ_CP047962.1\|WP_041207118.1\|35902_36706_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|182878
NZ_CP047962.1\|WP_161506693.1\|18199_20263_-\|potassium-transporting-ATPase-subunit-KdpB	unknown	unknown	gnl\|CDD\|234905
NZ_CP047962.1\|WP_005326326.1\|17428_17944_-\|potassium-transporting-ATPase-subunit-C	unknown	unknown	gnl\|CDD\|376890
NZ_CP047962.1\|WP_161506702.1\|38836_40954_-\|bifunctional-GTP-diphosphokinase/guanosine-3',5'-bis-pyrophosphate-3'-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236843
NZ_CP047962.1\|WP_161506697.1\|24905_25694_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223377
NZ_CP047962.1\|WP_161506692.1\|14703_17292_-\|sensor-histidine-kinase-KdpD	unknown	unknown	gnl\|CDD\|225115
NZ_CP047962.1\|WP_042650651.1\|33870_34461_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP047962.1\|WP_161506698.1\|26165_27515_-\|glutathione-disulfide-reductase	unknown	unknown	gnl\|CDD\|235701
NZ_CP047962.1\|WP_005326341.1\|29671_32752_-\|multidrug-efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|169983
NZ_CP047962.1\|WP_161506694.1\|20330_22010_-\|potassium-transporting-ATPase-subunit-KdpA	unknown	unknown	gnl\|CDD\|235494
NZ_CP047962.1\|WP_161506696.1\|23849_24854_+\|NADP-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|176191
NZ_CP047962.1\|WP_161506691.1\|13956_14640_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_CP047962.1\|WP_161506700.1\|36901_37942_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|182697
NZ_CP047962.1\|WP_005326342.1\|32767_33874_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273776

Protein	Function_ID	Function_description	E-value
NZ_CP047962.1\|WP_161507809.1\|35366_35840_+\|ricin-type-beta-trefoil-lectin-domain-protein	gnl\|CDD\|214672	smart00458, RICIN, Ricin-type beta-trefoil. Carbohydrate-binding domain formed from presumed gene triplication.	2.3014e-07
NZ_CP047962.1\|WP_139750694.1\|22974_23838_+\|alpha/beta-fold-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	5.58618e-29
NZ_CP047962.1\|WP_161506701.1\|37931_38678_-\|tRNA-(guanosine(18)-2'-O)-methyltransferase-TrmH	gnl\|CDD\|236837	PRK11081, PRK11081, tRNA guanosine-2'-O-methyltransferase; Provisional.	6.84745e-155
NZ_CP047962.1\|WP_161506695.1\|22340_22784_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	4.90202e-31
NZ_CP047962.1\|WP_161506699.1\|27591_29550_-\|PAS-domain-S-box-protein	gnl\|CDD\|226654	COG4191, COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms].	1.02426e-33
NZ_CP047962.1\|WP_043132721.1\|12824_13952_+\|multidrug-effflux-MFS-transporter	gnl\|CDD\|340878	cd17320, MFS_MdfA_MDR_like, Multidrug transporter MdfA and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as MdfA (also called chloramphenicol resistance pump Cmr), EmrD, MdtM, MdtL, bicyclomycin resistance protein (also called sulfonamide resistance protein), and the uncharacterized inner membrane transport protein YdhC. EmrD is a proton-dependent secondary transporter, first identified as an efflux pump for uncouplers of oxidative phosphorylation. It expels a range of drug molecules and amphipathic compounds across the inner membrane of E. coli. Similarly, MdfA is a secondary multidrug transporter that exports a broad spectrum of structurally and electrically dissimilar toxic compounds. These MDR transporters are drug/H+ antiporters (DHA) belonging to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.45132e-77
NZ_CP047962.1\|WP_041207118.1\|35902_36706_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|182878	PRK10976, PRK10976, putative hydrolase; Provisional.	3.19168e-98
NZ_CP047962.1\|WP_161506693.1\|18199_20263_-\|potassium-transporting-ATPase-subunit-KdpB	gnl\|CDD\|234905	PRK01122, PRK01122, potassium-transporting ATPase subunit KdpB.	0
NZ_CP047962.1\|WP_005326326.1\|17428_17944_-\|potassium-transporting-ATPase-subunit-C	gnl\|CDD\|376890	pfam02669, KdpC, K+-transporting ATPase, c chain. This family consists of K+-transporting ATPase, c chain, KdpC. KdpC forms strong interactions with the KdpA subunit, serving to assemble and stabilize the Kdp complex. It has been suggested that KdpC could be one of the connecting links between the energy providing subunit KdpB and the K+-transporting subunit KdpA. The K+ transport system actively transports K+ ions via ATP hydrolysis.	1.11815e-63
NZ_CP047962.1\|WP_161506702.1\|38836_40954_-\|bifunctional-GTP-diphosphokinase/guanosine-3',5'-bis-pyrophosphate-3'-pyrophosphohydrolase	gnl\|CDD\|236843	PRK11092, PRK11092, bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase.	0
NZ_CP047962.1\|WP_161506697.1\|24905_25694_+\|SDR-family-oxidoreductase	gnl\|CDD\|223377	COG0300, DltE, Short-chain dehydrogenases of various substrate specificities [General function prediction only].	1.68295e-87
NZ_CP047962.1\|WP_161506692.1\|14703_17292_-\|sensor-histidine-kinase-KdpD	gnl\|CDD\|225115	COG2205, KdpD, Osmosensitive K+ channel histidine kinase [Signal transduction mechanisms].	0
NZ_CP047962.1\|WP_042650651.1\|33870_34461_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.06151e-14
NZ_CP047962.1\|WP_161506698.1\|26165_27515_-\|glutathione-disulfide-reductase	gnl\|CDD\|235701	PRK06116, PRK06116, glutathione reductase; Validated.	0
NZ_CP047962.1\|WP_005326341.1\|29671_32752_-\|multidrug-efflux-RND-transporter-permease-subunit	gnl\|CDD\|169983	PRK09579, PRK09579, multidrug efflux RND transporter permease subunit.	0
NZ_CP047962.1\|WP_161506694.1\|20330_22010_-\|potassium-transporting-ATPase-subunit-KdpA	gnl\|CDD\|235494	PRK05482, PRK05482, potassium-transporting ATPase subunit A; Provisional.	0
NZ_CP047962.1\|WP_161506696.1\|23849_24854_+\|NADP-dependent-oxidoreductase	gnl\|CDD\|176191	cd05289, MDR_like_2, alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases. Members identified as zinc-dependent alcohol dehydrogenases and quinone oxidoreductase. QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR actin the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	1.34553e-133
NZ_CP047962.1\|WP_161506691.1\|13956_14640_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.81942e-75
NZ_CP047962.1\|WP_161506700.1\|36901_37942_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|182697	PRK10749, PRK10749, lysophospholipase L2; Provisional.	6.68215e-107
NZ_CP047962.1\|WP_005326342.1\|32767_33874_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	5.47022e-74

>NZ_CP047962.1|WP_161506697.1|24905_25694_+|SDR-family-oxidoreductase
MTTLPTIFITGASSGIGATYAERFARRGHDLVLVARNKSRLDALAMRLREQHQIAVEVLQADLTNSAELPALETRLRHDARIGILINNAGMPQSGHFLEQSPEAIESQIALNITALTRLAAAIAPRLAQSGTGSIVNIGSVVGFSPEFGISLYGATKAYVLFLSQGLAHELSPQGVYVQAVLPATTRTEIWAHAGVDVNTLPEVMEVGELVDAALVGFDRRELVTIPPLHVAERWTALDDARQGLMSDLRQAHAAERYQPQA
>NZ_CP047962.1|WP_161506696.1|23849_24854_+|NADP-dependent-oxidoreductase
MKALTFKRYGKSPEIGITDLPCPALKADEMLVQVYAAGLNPIDNMIPTGMFKPVLHFQLPATLGSDLAGVVTEVGSQVTRFKPGDAVFASIFDHGSGSLAEFAVVPERAAALKPANLDFVQAASIPMVGLTSWQALKERANLQAGQKVFIPAGSGGIGTFAIQLAKLLGAKVGTTVSTGNIELVRELGADEVVDYKQQAFEHQLHGYNAVLGTVRGDAIEKAIDILKPGSKIISLTGPLDAAFARARGLNVLLRLLFGLMSRKIRSRAKKRNVAYSFLFVRPDGDQLTEIGELLDAQRIKPVIDKVFPFDQAKEALEYLAKGHARGKVVVSIKP
>NZ_CP047962.1|WP_139750694.1|22974_23838_+|alpha/beta-fold-hydrolase
MHWKDVPTRTLDVNGTSFAYRALGPDTGVPVIFLHHLMAVLDDWDPGVIDGIAAKRRVIAFDNRGVGASGGSVPHTIEEMGRDAIAFIRAMGLSQVDLLGFSLGGGVAQMVALQAPDLVRRIVLAGTGPRGGGGIDEINKIAATAYLKAALTLKDPRHFLFFPRTPDGKRAAKEYFSRLKARTTDRDQPISLQARYAQLKAIRSAGLSAPDDLSVITQPVFVANGDHDLMVDSRLSADMARRLPNARLTIYPDSGHGGIFQHYRAFVPEVLAFLADDADLTPMHSQG
>NZ_CP047962.1|WP_161506695.1|22340_22784_-|helix-turn-helix-transcriptional-regulator
MNMKKSYDTPCPIARSMAIAGDAWSILILRDAHAGLTRFDQFRKNLGIAPTMLTRRLATLTEEGLLEKRLYSEHPPREEYLLTAAGRDFLPILFMIGEWGRQYRGDDNMIRFFDMEAGTEIKAIVVDEVTGAKIGTRPLRVVMPDEN
>NZ_CP047962.1|WP_161506694.1|20330_22010_-|potassium-transporting-ATPase-subunit-KdpA
MWQEIIYPVAFVLLVLLPAPLLGSYMYRVFEGKSRWLAPVERATLACCGTDGREQDWKSYALSLLAFNGAGFGLLFLILMAQGLLPLNPQQLPGLNWQLAFNTAVSFMTNTNWQAYSGEASLSYFSQMVGLTTQNFVSAATGATVAIALFRGLSRQQTIHLGNFWQDLVRFCLYVLLPMALLMALLLVSQGVPQSLSAYLPFHALEGQEQLLPLGPAASQIAIKQLGSNGGGFFGVNSAHPFENPTALSNWLEMVALLTIPAALVCTLGRYVKDTGHGRAILTAMTLLFVLGLGLSVYQELQPDPALAQLTTQAGNWEGKESRFGPVLSSIWEVATTSASNGSVNAMHDSFTPLGGMVGMINMLLGEVIFGGVGAGIYGMMLFVLLTVFLCGLMVRRTPTYLGKRLGITEMKWVVASMLVMPVGVLVIGGVTLLMPDATTIMGHDGPHGLSRLIYAYASAAGNNGSAFGGFAAADNWQCVAIGLAMLLGRFGYIIPVLAIAGQLSRASQQDAGEGDFPIRGPLFITLLIITVLLIGGLSFLPVLALGPVAEHLLILGAL
>NZ_CP047962.1|WP_161506693.1|18199_20263_-|potassium-transporting-ATPase-subunit-KdpB
MSKSISIPARTEKVKGKGKKQTSQVVQAMIEAFYRFNPRALFGSPILFTLWLAAVMATLESLLGQPLSGVTPSLAWQLTAWLWLTLWFANFAETLAEGRGKARADSLKAGMSQLQARKVRDPKDGQGEWIPATSLQKGDLVLVRSGEMIPADGEVVAGIASVNEAAITGESAPVIRESGTDRSGVTGNTTVVSDEIWVRVTNNPGESTLDRMIALVEGAKRQKTPNEMALDALLVGLTLIFLLVVATLPWFLDYNGTQVPRLYLLALFITLIPTTIGGLLSAIGIAGMDRLVKLNVIAKSGRAVEAAGDVRTLLLDKTGTITFGNRMADELIPAPGVDPSLLAQAAMLASLGDNTPEGKSILTLAGKSMAKPSQLESDKVIPFSAETRLSGLDRNGHQYRKGAVDAVLNYLSLDRKGVPELILKSVDNIARQGGTPLLVCTHEQLLGVVYLKDIIKPGIKARFQILRHMGIRTVMITGDNPLTAAAIAAEAGVDDFIAEATPEKKLAYIRQEQADGRMVAMCGDGANDAPALAQADVGLAMNEGTQAAKEAGNLVDLDSNPTKLLDVVLVGKQLLVTRGALTTFSIANDVAKYFAILPALFIAAYPQLGALNLMQLGSPESAILSAIIFNALIIVALVPLALRGVNVKGSAASLLRRNLLIYGLGGLIVPFIGIKLIDLVITGLGLV
>NZ_CP047962.1|WP_005326326.1|17428_17944_-|potassium-transporting-ATPase-subunit-C
MIAIRTLLTLTLLLGVGYPLAVTGLAQLFFPWQANGSQLTDAKQQLVGSALLAQKFERAEYFHSRPSASDFTTIGSGASNLGVSSPLRSEFAKAQGNYQSPAMLTRSGSGLDPHLPLDAVLAQVDRVAKQRGLDPASLTEQVKSSTQAGILGPQVVNILQLNLLLDQHKDA
>NZ_CP047962.1|WP_161506692.1|14703_17292_-|sensor-histidine-kinase-KdpD
MRDEARADALLASLEQEHKGKLKVFLGAAPGVGKTYAMLQAVREQAREGVDILIGVVETHGRQETLALLDKLAIQPRKLHHHRQQRLEEMDLDGLLERKPAIVVVDELAHTNAPGSRHEKRWQDVEELLGAGIDVYSTLNVQHLESLNDLVWQLTGVRVKETLPDQVLLEADSIVLIDLPPKELLGRLKEGKVYVPHQAKAALQSFFSLNNLTALRELAMQTAASHVEGDLQLQWQAAGKTTLPLRGKLMVCLGDQHGAALVRYGHRFAQRRQLPWLVVHIDSKGQRSPELEQALALASQLGARVLTLSSPAVADALLETAEQQQVSQLLLGKPHSPPWRLSLVQHLLKQAQGFEITLVDTGKRKPSLKLHPAGPREIRQSLLALLIMGTTSAIAWGFSHWLPSASLPLLFVLGVLATALSTSLVPAILAAVLGFVGHNLLFTAPYFSLSVANHSDLLNLFVLLIVGMTAGRLASRQRQQLVGLRETQQLGNALLSLSQGLATASSPVEVLRQGTQAISLALGQPVFALDEEYQYRAGDEVRGPGQTDKAAIDWCLAQKQSAGAHTATLNAAEAQYHHLTDELVLGIRLASPLASSAEHQLQALLTDIRAALARIDLNERLADSQLQAETDRMRAALLSSVSHDLKTPLATIMGAGSTLLEYGDRISAEDRNELLHSVQEEARRLHSYVQNLLDMTRIGSPDFQLKREWVDLADLVESARKRLDSSWRQHRLLIHFDQQIPQLYVHGALIEQVLVNILDNASRYSPAGTPIEFKVMLADPDLIIDIIDIGVGIAESDRDKIFNLFYTQPVGDCGSRGTGLGLAISRAMIEAHGGRIWAFSGPNGNGTCMRISLPLSLNAPEV
>NZ_CP047962.1|WP_161506691.1|13956_14640_-|response-regulator-transcription-factor
MAHILVIDDEAAIRRFLRISLVAEGHQVSEAVGVNEGLAQYRHLNPDLVILDLGLPDGDGIQILQAIREHHPNPVLVLSARDSEQEKVRLLDAGANDYMSKPFGIGEMMARIRALLRQRAGVSSGECRHFPQCGLSLDTGSHKVTMKDEEISLSRKEFALLQALVCHPGKLVMQTQLLNDIWGPSHKEDTHYLRIVIASLRKKLGDNPQQPSLIETEPGIGYRFIGS
>NZ_CP047962.1|WP_043132721.1|12824_13952_+|multidrug-effflux-MFS-transporter
MNNKLPPLWLVVGLMMFPQIVETIYSPALTQIATQFRVSDGQASQTLSVYFLAFAVGVVCWGRLCDLIGRRPAMLAGLLTYGLGTLLALLATEFETLLLARIISAFGAAVGSVVTQTMLRDSYQGSDLAKVFSVMGAALSISPVLGLVSGGLLAEQFGYLGVFSGLMVLALVLGLIASWRLPETRPETTTSIALWPLACRMARDGGLWRSALLVALFNTMLFGYYSLAPFLFAEQGWSASEFGYSGAVLALATLLGSLLNKRLLGKGWQPASLIQLAASLALGAGAAVWASQSSLWFLLPMMGVVVAYGIAIPNVLSQALLAYREVAGSAGALFGLAYYLLLSLGLALAAGLQDLGLLILGCGLVAVLCSGRRST
>NZ_CP047962.1|WP_161506698.1|26165_27515_-|glutathione-disulfide-reductase
MAQHFDYIAIGGGSGGIASANRAAMYGKKVALIEAKELGGTCVNVGCVPKKAMWYAGQIADALRYGSDYGFDTTLNHFSWARLVESRQAYIGRIHQSYENVLGKNQITVIKGFARFVSSNTIEVDGEQYSADHILIATGGRPEVPTIPGAEFGIDSDGFFELQAQPKRVAVVGAGYIAVEIASVMQALGSETHLVVRKHAPLRNFDPMIHETLVEIMAQEGPRLHTHAVPKAVVKNADDSLTLQLEDGRHLTVDCLIWAIGRVPATDNLNLAATGITLDEQDFIPTDKFQNTAVANLYAVGDNTGRIQLTPVAVAAGRRLSERLFNNKPNEHLNYDLVPTVVFSHPPIGTIGLTEPEAIAEYGESQVKVYRSQFTAMYSALTQHRQPTRMKLVCVGPEEKVVGLHGIGFAMDEILQGFGVAMKMGATKADFDNCVAIHPTSAEEFVTMR
>NZ_CP047962.1|WP_161506699.1|27591_29550_-|PAS-domain-S-box-protein
MSGIFSRAFGLNGLSYRLLSYILICSTVLALVITVLQLAWDYNKDVTVIEASIDQIEASFLQPISASLWNLDEEQVKVQIEGIMNLPNMQFVMVKEMLGNSEVPLLTQGVEQAQYDISREFSLTYQGEVVGKLFVAATLEQVYQRLIEKSVLILVSQTIKTLVVSLCILVIIYYLVIRHINRIVSYAQKLSLDRLAVELTLEGRPLPRKHPDEFDALAATLNQMRTRLNDEFTARHQAADQLQQERDFSATLINSANMVICCMEPDLNIASINPAAILLTGYHHEELLQHNWLDLFVSQEQRAELAAILSDQGSLDDREIIMHDQQGHELVLQWTFAPFYEGPNLKYLIGFGYDITRLKKVEREITLFNEQLEGKVVERTRSLSDANDQLGKAYDDLKQAQQTLVESEKMASLGSLVAGVAHEINTPIGISVTASSYLQEQVADFKQHLEAKQLSRSYLNEFTQNLDESMQLLQGNLRRASELIASFKQVAVDQSSEARYNFSLADNLHQVVVSLGYKLKKAQCEVDIQCDPKLAIYSFPGSFTQIYSNLILNSIHHGFDGWDRPKKITIRVEQQGDELVIDYSDNGRGIPPEILPRIFDPFVTSKRGQGGSGLGTHIIYNLVVQLLRGRIHCASEPGQGAQFHIRLPIQQN
>NZ_CP047962.1|WP_005326341.1|29671_32752_-|multidrug-efflux-RND-transporter-permease-subunit
MRFTDIFIKRPVLAISLSFLIALLGFQAIFKMQVREYPEVINTVITVNTSYYGASSDLIQGFITQPLEQAVAQADNIDFMTSSSQLGSSTVTAYMKLNTDPNAALSDILAKVNSVRSQLPKEAEDPSVTSSTGSTTAVLYMGFTSPELNSSQITDYLERVIKPQLFTVGGVSKVDLYGGVEFALRVWLDPAKMAAFDLTASDVMTVLNSNNYQSATGQATGYFTLFNGNAETQVSNTDELKRLVVATRDGKVIRLSDIAKVSLEKSHDIYRASANGREAVVLAINAAPTANPINIAHDVLELLPSLKSNMPSTMQVNILYDSTIAINESIHEVIKTILEAAAIVLVVITLFLGSFRAVIIPIITIPLSLIGVVMMMDMFGFSINLMTLLAMVLAIGLVVDDAIVVLENVDRHIKEGEEPFRAAIIGTREIAVPVIAMTVTLAAVYAPIALMGGITGSLFKEFALTLAGAVFVSGIIALTLSPMMCAKMLRANETPSKFESTVHHLLDRMTARYDSMLHAVMQKRIVVILFAVIVFGSLPLLFKFIPSELAPSEDKGVMAVLGTAPSNANLDYIENTMADVNKVLDDQPEIAYSQVFSGVFNANQAFGIASMVPWSQREASQKEVLDRVAGLVKDIPGMAITTFQFPELPGASSGLPIQFVITTPNSFESLFLIAGEMLAATQANGQFVYSDLDLNYDSATMKISIDKDKAGAYGITMQDIGTTMGTMMADGYVNRIDLDGRSYEVIPQVERKYRLNPESIKGYYVRAADGKSIPLGSLIKIEVVGEPRALPHFNQLNSATIGAVPAPGVAMGDAINWFKATAEEKLPQGYRYDFMGEARQFVTEGNALYATFALALAIIFLVLAIQFESVRDPLVIMVSVPLAISGALIALAWGMATMNIYSQVGLITLVGLITKHGILICEVAKEEQLLHGMNRMQAVMQAAKVRLRPILMTTAAMIAGLIPLLYAAGAGAAQRFSIGIVIVAGLAIGTLFTLFVLPVIYTFLASEHKPLPEFDESIPAKAKGSH
>NZ_CP047962.1|WP_005326342.1|32767_33874_-|efflux-RND-transporter-periplasmic-adaptor-subunit
MKKWMAIMLLIALALFGSVIGFNMFKQKKIAEFMANRPEPEFPVTAMVTKAQDWVPTIEAIGFIEPNQGVTLSSELAGTIDKISFESGAQVKADQLLLSLDSSVEKANLNSSQARLPAARAKFQRYQNLYQKNSISRDQLDDAEASYRSLEADIESLKGTINRREVRAPFGGVVGLRNVFLGQYLEPGTEIVRLEDTSVMRLRFTVPQTDISKISLGQTIKINVDAYPQTQFDGQITAIEPAVNYQSGLIQVQANIPNNGGQLRSGMFARASIILPTVKDQIVIPQSAISFTLYGENVYVIHEADGVKRAKQVVVKAGERRGNDVHVLSGIKAGDQIVLSGQVRLSNDTKVHVVDNDALAVPAQTPML
>NZ_CP047962.1|WP_042650651.1|33870_34461_-|TetR/AcrR-family-transcriptional-regulator
MDKKERIFEAAHEILGEQGFYGLSIAMVAKKAKVAAGTIYRYFSDKDDLVRQLYLHTILKCHPQIMEGVQIEEVSYRQYRRLWLNIDAIFTNYPNALKCKLQYESSPLGAELERDPVIMATWAPLERFFEQGRQQGLFIDLPVLVLQALSLDCVANLAQQRRVHDFVLTQEQLETVIRASWNAILNPNHSITGACS
>NZ_CP047962.1|WP_161507809.1|35366_35840_+|ricin-type-beta-trefoil-lectin-domain-protein
MALLLGGCALPPRPENLLLEAASSSIPIPPATLVTDGGFCVALNEQGHLLTQPCDQGPNQLFSWDAGALLLAQGCLIATGTDGLVVGGCENDSHQWQWQGDRLFNRQVSLCLDVAGRRHRSAVPLRLAECYGGANQSFTWTPTGSLLERLMPPSSIW
>NZ_CP047962.1|WP_041207118.1|35902_36706_-|Cof-type-HAD-IIB-family-hydrolase
MFKVVVSDLDGTLLNGQHQISPRTRDTLHRLVDQGIKFVVATGRHHVDVRSIRDALGLDIYLITSNGAVVHDKQDSLVFNQALPSTVAAELIALERDPSIHINVYYGDEWLVEEEMPWLLQFHHDSGFSYRLTDLASHPLDKINKVFYIGEHEKLLQIEAELNQRYGDRINVTFSLPDCLEVMHAGVHKGNAVRAVLEQHGLEMSQAVAFGDGMNDFEMLSMVGRGVVMGNAHDRLKLALPNHDQTLSSDEDGVAVYLERLFAPVVA
>NZ_CP047962.1|WP_161506700.1|36901_37942_-|alpha/beta-fold-hydrolase
MKFNALPLLALTLFSAGALAVTNPYQLTTEADVPALHQQTLPDFWRDHAAPGEFKGKDGVTIRYAALRQTKVDRAILLVNGRVESYLKYQELAWDLWRQGYSLYLIDHRGQGLSDRLLADKEKGYVADFDDYVLDLKQFHDEVILADKPAKLFLLAHSMGGAISARYLERWPDDVEAAVLSSPMMGINLGGLPKWLAQGLAATMDTVGSWWGEPPYGPGQTGYVSHEFADNGLSHSESRYQAFRQLYEQHPQIKLGGVTAHWIREGIKAGDAAIAEADRIKTPLLLIQAGEDGIVDNQAQNSFCARLQCEGGKPLRIEGAWHELFIEADAQRLPALTATLDFFARF
>NZ_CP047962.1|WP_161506701.1|37931_38678_-|tRNA-(guanosine(18)-2'-O)-methyltransferase-TrmH
MTPERFKRISDMLAQRQLDLTVCMEEVHKPHNLAAIVRTADAIGIHRVHAVWPKTWIHKRKGTARGSQNWVDVKLHPDIGSAVAELKASGMQILATHLSESSVDFRAIDYTKPTAILVGQEKHGIGEEALALADHHIVIPMVGMVQSLNVSVAAAAILYEAQRQRELAGCYQRGCPLDLEEQNSILFEGGYPIYAQLCKEKDMPYPQLGPAGEILADEDWWQRMQLTRKGWAAQQDDPLDMEYPTDEV
>NZ_CP047962.1|WP_161506702.1|38836_40954_-|bifunctional-GTP-diphosphokinase/guanosine-3',5'-bis-pyrophosphate-3'-pyrophosphohydrolase
MYLFENLKEIASSYLPSEQVEKLRQAYVVARDAHQGQMRSSGEPYITHPVAVARILGDMRLDHETLMAAVLHDVIEDTPVTKDDLAELFGNAVAELVSGVSKLDKLKFRDRKEAQAENFRKMVMAMTQDIRVILIKLADRTHNMRTLGSLRPDKRRRIARETLEIFAPIANRLGIHTMKNELEELGFEALYPMRSRVLRESVRRARGNRREIIDSIESEIEGRLREAGIDAQVSGREKNLFSIYNKMEKKELQFHEVMDIYAFRVRVKDIDTCYRVLGQMHSLYKPRPGRFKDYIAIPKSNGYQSLHTSLVGPHGVPVEVQIRTEFMDQMADKGVAAHWAYKQDGDSSGTTAQIRAQRWMQSLLELQQSAGSSFEFIEGVKTDLFPDEIYVFTPEGRIMELPAGATPVDFAYTVHTDIGHACVGSRVDRHPYPLSSPLHSGQTVEIITAPGARPNAAWLNFVVTTKARSKIRQFLKNLRTEESVVLGRRLLNHALGAKNIEDIPEPRIKQVLADTKHENLQGLLADVGLGNAMSVMVARRMLGDELPPEEQPKSSCKKMPIKGADGMLVTFANCCRPIPGDAIIAHISPGKGLVIHQESCRNIKGYSREPDKYLPVQWEVDKDQEQEFRTGISIEIVNHQGALAELANVIAATGANIHAISTEEKDGRVYLVTLLITTKGRIHLANIMRKIRVMPNVLRVSRQKN

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Crispr_ID: NZ_CP047962_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047962_2

1684859-1684980

Orphan

Consensus_repeat	Method
ATAGATCCCCTGTGCGACGCCATCGCCAAGGTG	CRISPRCasFinder

1 spacers

DinG

The CRISPR arrays of NZ_CP047962_2

>merge|NZ_CP047962|2|1684859-1684980|CRISPRCasFinder
ATAGATCCCCTGTGCGACGCCATCGCCAAGGTGCTGTAACTGAGGCGAAGAGGTTCTATGCGGGAATCACCCGCGTCAATATCAATAGAATAGATCCCCTGTGCGATGCCATCGCCAAGGTG

>NZ_CP047962|2|2|1684859-1684980|CRISPRCasFinder
ATAGATCCCCTGTGCGACGCCATCGCCAAGGTG	CTGTAACTGAGGCGAAGAGGTTCTATGCGGGAATCACCCGCGTCAATATCAATAGA
ATAGATCCCCTGTGCGATGCCATCGCCAAGGTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047962.1\|WP_161507023.1\|1671561_1672929_-\|alkaline-phosphatase	unknown	unknown	gnl\|CDD\|224699
NZ_CP047962.1\|WP_161507028.1\|1678876_1680949_-\|ATP-dependent-DNA-helicase-DinG	DinG	COG1199_DinG_CAS-IV-A	gnl\|CDD\|236966
NZ_CP047962.1\|WP_161507029.1\|1681332_1682406_+\|porin	unknown	unknown	gnl\|CDD\|225744
NZ_CP047962.1\|WP_005331987.1\|1694532_1694733_+\|Trm112-family-protein	unknown	unknown	gnl\|CDD\|225391
NZ_CP047962.1\|WP_161507034.1\|1688132_1688627_-\|DUF2062-domain-containing-protein	unknown	unknown	gnl\|CDD\|378263
NZ_CP047962.1\|WP_161507024.1\|1674670_1675621_+\|ribosome-biogenesis-GTPase-YlqF	unknown	unknown	gnl\|CDD\|236570
NZ_CP047962.1\|WP_161507022.1\|1670827_1671511_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047962.1\|WP_161507032.1\|1685114_1686452_+\|IS4-like-element-ISAeme15-family-transposase	unknown	unknown	gnl\|CDD\|379017
NZ_CP047962.1\|WP_005331989.1\|1693386_1694382_+\|tetraacyldisaccharide-4'-kinase	unknown	unknown	gnl\|CDD\|234808
NZ_CP047962.1\|WP_161507030.1\|1682619_1683561_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047962.1\|WP_161507021.1\|1670009_1670783_-\|amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|366132
NZ_CP047962.1\|WP_161507027.1\|1678072_1678732_-\|DUF2057-domain-containing-protein	unknown	unknown	gnl\|CDD\|378258
NZ_CP047962.1\|WP_161507025.1\|1675794_1676943_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|179614
NZ_CP047962.1\|WP_161507026.1\|1677102_1677999_-\|histone-deacetylase	unknown	unknown	gnl\|CDD\|212519
NZ_CP047962.1\|WP_005331991.1\|1691617_1693387_+\|lipid-A-ABC-transporter-ATP-binding-protein/permease-MsbA	unknown	unknown	gnl\|CDD\|183016
NZ_CP047962.1\|WP_005331986.1\|1694729_1695479_+\|3-deoxy-manno-octulosonate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|235473
NZ_CP047962.1\|WP_161507830.1\|1689167_1691429_+\|DNA-internalization-related-competence-protein-ComEC/Rec2	unknown	unknown	gnl\|CDD\|236924
NZ_CP047962.1\|WP_161507035.1\|1688620_1689139_-\|DUF2062-domain-containing-protein	unknown	unknown	gnl\|CDD\|378263
NZ_CP047962.1\|WP_041206003.1\|1695689_1696334_+\|UvrY/SirA/GacA-family-response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|236538
NZ_CP047962.1\|WP_161507033.1\|1686500_1688006_-\|DUF853-family-protein	unknown	unknown	gnl\|CDD\|283518

Protein	Function_ID	Function_description	E-value
NZ_CP047962.1\|WP_161507033.1\|1686500_1688006_-\|DUF853-family-protein	gnl\|CDD\|283518	pfam05872, DUF853, Bacterial protein of unknown function (DUF853). This family consists of several bacterial proteins of unknown function. BMEI1370 is thought to be an ATPase.	0
NZ_CP047962.1\|WP_161507028.1\|1678876_1680949_-\|ATP-dependent-DNA-helicase-DinG	gnl\|CDD\|236966	PRK11747, dinG, ATP-dependent DNA helicase DinG; Provisional.	0
NZ_CP047962.1\|WP_161507029.1\|1681332_1682406_+\|porin	gnl\|CDD\|225744	COG3203, OmpC, Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane].	1.5091e-28
NZ_CP047962.1\|WP_005331987.1\|1694532_1694733_+\|Trm112-family-protein	gnl\|CDD\|225391	COG2835, COG2835, Uncharacterized conserved protein [Function unknown].	2.27803e-17
NZ_CP047962.1\|WP_161507034.1\|1688132_1688627_-\|DUF2062-domain-containing-protein	gnl\|CDD\|378263	pfam09835, DUF2062, Uncharacterized protein conserved in bacteria (DUF2062). This domain, found in various prokaryotic proteins, has no known function.	1.01903e-27
NZ_CP047962.1\|WP_161507024.1\|1674670_1675621_+\|ribosome-biogenesis-GTPase-YlqF	gnl\|CDD\|236570	PRK09563, rbgA, GTPase YlqF; Reviewed.	4.49145e-151
NZ_CP047962.1\|WP_161507032.1\|1685114_1686452_+\|IS4-like-element-ISAeme15-family-transposase	gnl\|CDD\|379017	pfam13006, Nterm_IS4, Insertion element 4 transposase N-terminal. This family represents the N-terminal region of proteins carrying the transposase enzyme, DDE_Tnp_1 (that was Transposase_11), pfam01609, at the C-terminus. The full-length members are Insertion Element 4, IS4. Within the collection of E.coli strains, ECOR, the number of IS4 elements varies from zero to 14, with an average of 5 copies/strain.	6.94821e-32
NZ_CP047962.1\|WP_005331989.1\|1693386_1694382_+\|tetraacyldisaccharide-4'-kinase	gnl\|CDD\|234808	PRK00652, lpxK, tetraacyldisaccharide 4'-kinase; Reviewed.	2.0377e-167
NZ_CP047962.1\|WP_161507023.1\|1671561_1672929_-\|alkaline-phosphatase	gnl\|CDD\|224699	COG1785, PhoA, Alkaline phosphatase [Inorganic ion transport and metabolism].	4.38695e-117
NZ_CP047962.1\|WP_161507021.1\|1670009_1670783_-\|amino-acid-ABC-transporter-substrate-binding-protein	gnl\|CDD\|366132	pfam00497, SBP_bac_3, Bacterial extracellular solute-binding proteins, family 3.	7.55083e-13
NZ_CP047962.1\|WP_161507027.1\|1678072_1678732_-\|DUF2057-domain-containing-protein	gnl\|CDD\|378258	pfam09829, DUF2057, Uncharacterized protein conserved in bacteria (DUF2057). This domain, found in various prokaryotic proteins, has no known function.	1.57292e-49
NZ_CP047962.1\|WP_161507025.1\|1675794_1676943_+\|MFS-transporter	gnl\|CDD\|179614	PRK03633, PRK03633, putative MFS family transporter protein; Provisional.	0
NZ_CP047962.1\|WP_161507026.1\|1677102_1677999_-\|histone-deacetylase	gnl\|CDD\|212519	cd09993, HDAC_classIV, Histone deacetylase class IV also known as histone deacetylase 11. Class IV histone deacetylases (HDAC11; EC 3.5.1.98) are predicted Zn-dependent enzymes. This class includes animal HDAC11, plant HDA2 and related bacterial deacetylases. Enzymes in this subfamily participate in regulation of a number of different processes through protein modification (deacetylation). They catalyze hydrolysis of N(6)-acetyl-lysine of histones (or other proteins) to yield a deacetylated proteins. Histone deacetylases often act as members of large multi-protein complexes such as mSin3A or SMRT/N-CoR. Human HDAC11 does not associate with them but can interact with HDAC6 in vivo. It has been suggested that HDAC11 and HDAC6 may use non-histone proteins as their substrates and play a role other than to directly modulate chromatin structure. In normal tissues, expression of HDAC11 is limited to kidney, heart, brain, skeletal muscle and testis, suggesting that its function might be tissue-specific. In mammals, HDAC11 proteins are known to be involved in progression of various tumors. HDAC11 plays an essential role in regulating OX40 ligand (OX40L) expression in Hodgkin lymphoma (HL); selective inhibition of HDAC11 expression significantly up-regulates OX40L and induces apoptosis in HL cell lines. Thus, inhibition of HDAC11 could be a therapeutic drug option for antitumor immune response in HL patients.	6.68478e-134
NZ_CP047962.1\|WP_005331991.1\|1691617_1693387_+\|lipid-A-ABC-transporter-ATP-binding-protein/permease-MsbA	gnl\|CDD\|183016	PRK11176, PRK11176, lipid A ABC transporter ATP-binding protein/permease MsbA.	0
NZ_CP047962.1\|WP_005331986.1\|1694729_1695479_+\|3-deoxy-manno-octulosonate-cytidylyltransferase	gnl\|CDD\|235473	PRK05450, PRK05450, 3-deoxy-manno-octulosonate cytidylyltransferase; Provisional.	2.55943e-155
NZ_CP047962.1\|WP_161507830.1\|1689167_1691429_+\|DNA-internalization-related-competence-protein-ComEC/Rec2	gnl\|CDD\|236924	PRK11539, PRK11539, ComEC family competence protein; Provisional.	2.13937e-112
NZ_CP047962.1\|WP_161507035.1\|1688620_1689139_-\|DUF2062-domain-containing-protein	gnl\|CDD\|378263	pfam09835, DUF2062, Uncharacterized protein conserved in bacteria (DUF2062). This domain, found in various prokaryotic proteins, has no known function.	3.58597e-47
NZ_CP047962.1\|WP_041206003.1\|1695689_1696334_+\|UvrY/SirA/GacA-family-response-regulator-transcription-factor	gnl\|CDD\|236538	PRK09483, PRK09483, response regulator; Provisional.	5.13731e-165

>NZ_CP047962.1|WP_161507030.1|1682619_1683561_+|hypothetical-protein
MIDFSHPEWRALAQQLLGHSPVVIRGRQWQPLVGLLKDNQLLLAHGSNSYELTPAGRRYLTRELMLAEIATALPEPEEWLHAQGWQLGEQVNERVLAALYRKSDVNFTPNEQIDFEDKGIRLCADQLLRLRSAQPFSLFFSSGTLIDAAPWLQALGEVALPERTLAGLGKILWGEGNIERVITTDSVGAFAELLLESGCLLVWAPPSASLALQQVVAALPPNVLWSHLTALDPAGVDRVQALAQRLGRPASWWLPRDLAPIKEAYAAPLQDARPWEPSRIPRPLRAWCSDLVESNRGLSAEVCALASGWHAIG
>NZ_CP047962.1|WP_161507029.1|1681332_1682406_+|porin
MKKTILAIAIPALFASAANAAVIYDKDGTTFDIYGRVHAQYFGEYDSYDADAESYSKNDGELTTYARLGWSGKMALNDTWSGVAKTEWQLASENSYGSDKRELKARHIYAGFDGSQYGQFLFGQTETAFYNATVAKTDIFNDYGDMANVYDGCQEGQAIYNGQWNGFGLKGGYITNNGSYDANYAGWSGVEGKMDHGYTLGATYDFDFGLGLAAGYESKSFEDASTLTITSENGTFSRADLTDKNDWAVAASYTYQGFYFAALYNESTYKFDGFNDAKARGYELAASYNVDAWTFLAGYNFAEAKVEGVTSYEDTVDFTSMGVEYAFNSKLKAYTEYKIQGLSQQDDEWTVGMQYNF
>NZ_CP047962.1|WP_161507028.1|1678876_1680949_-|ATP-dependent-DNA-helicase-DinG
MLSTRLKATIRNTYRQIADGLPGFVPRKEQNFLVAEIAKTLTGEYEKSRRILVAEAGTGIGKSLSYAQGAIPVARLTQKKLVISTATVALQEQLIHKDLPFYHRHSELPFRFMLVKGRQRYCCEHLLEQAASGAEMANFELDFGSLSKHKPSDSDKERYQALWQAYTEGKWDGDRDNWPKPIPDLCWDRIAADRHSCNKALSHHQHCPFHRARNDMDAADVLVVNHALLLSDLTMGGGIILPPPDECIYVLDEAHHLPTIARDHGAASASIKGSRRWLEKLVQSAGKLARALNKESLIDPQLKLQDALASMQPDLKALEQWLAGNDHLFGSEQHHRFAEGVLPDPLPMLAENLKEASKKALRALDRMQGAIGEALKDGEIRRKEAEPLLAESGFHLQRLESFCALWEMLSRHVPTGKTPLARWMARSEDGDIWLHASPIEVGYLLEEWLWSRCLGAVLVSATLTALSSFSYFRHQVGLKEHDGTRYLRLRSPFEYHKAELYLPKMTHEPSAPGFTQELVDTLPRLLAGKEASLVLFSSYRQMNEVAVGLRAKGLSLLVQGEASRNALLTLHKQKCDGGQASILFGTGSFSEGLDLPGHYLTNLVITKLPFAVPNSPVEEATAEWVEKRGGNPFLQLTVPEASRKLIQACGRLIRKEADRGRVTILDRRLLTKRYGKGLLDALPPFTRRIE
>NZ_CP047962.1|WP_161507027.1|1678072_1678732_-|DUF2057-domain-containing-protein
MKLTVLVPALAGLLWAGSALADSQLEIHNPYVVQLIDGESINPKLLEKTSSFPISAGKHQVVVAFEGNYSNRNDIKLVTAEPLVINFTAGDNQTLMLDFKKPRNEDEAKAFVKEQKVVLKDRVSGQALASEQFVMPKVGGFQLTRDYQQELLKMGKAFNQPATVAVSSAAVMAAASAPVEVAPSKAQSNPEALTQLQSWYNKADAETRKAFQIWVIQQQ
>NZ_CP047962.1|WP_161507026.1|1677102_1677999_-|histone-deacetylase
MSLRIFYHPYYSSLTLPERHRFPLAKYQALFEHLGSLGYPLAEAAPATPEQIKRVHDAGYVEAALAGTLDDGAIRRLGFPWSPMLIERTLRSVGATVAASRHALEQGCGLQISGGYHHAHRDFGSGFCLFNDLVIAARACLDEGRCEQVLIVDLDVHQGDGSAALCTGSRDIITLSLHGEHNFPHHKPASHLDFPLPTGMQDDAYLETLTQALSLALRLYRPDLILYQAGVDVHQADELGYLSLSDAGVRQRDAMVFDCAISHGLPIAAVPGGGYRRDWRQLIPLHLSLFEEAKKRYG
>NZ_CP047962.1|WP_161507025.1|1675794_1676943_+|MFS-transporter
MITYSRPVLLLLCGLLLLTLAIAVLNTLVPLWLAHDNLPTWQVGMVGSAYFCGNLLGTLLAGALIKGAGFNRSYYLASALFAAACVGLGLTLGFWSWLTWRFIAGIGCAMIWVVVESALMCSGNARNRGRLLAAYMMVYYLGTVLGQLLVSTLPTALMDVLPWVTGLVLAAILPLLFTRIVNEQGEQQGATRVWPMLRLRQARLGVNGCIISGIVLGSLYGLMPLYLNHQGVSDAGIGYWMAVMVSAGILGQWPAGRLADRFGRLPVLRMQVLVVILGALAMLGNLAMGPALFILGAAGFTLYPVAMAWACEKVEQHQLVAMNQALLLSYTIGSLLGPAYTSLLMQHYSDKLLFIMIASVSFIYLLMLLRPVGEHPTPVAHA
>NZ_CP047962.1|WP_161507024.1|1674670_1675621_+|ribosome-biogenesis-GTPase-YlqF
MSINWFPGHMHKARKEIAEVMPQVDVIIEMLDARIPFSSENPLVPELRGDTPVIKVLNKADLADPAITELWVAHMEQEKGIKALPLTQQEPEKIKALLTLCHEMLPERNFDLRGVRAMIMGIPNVGKSTLINTLAGRIIARTGNEAGVTKSQQRIKLDNNVILTDTPGFLWPKLNPPSCGYRLAITAAIKDTVFDYADIAMFAADYFIKAYPERIKARYQITDLPETEIELLEMIARQRAFVRKGGLADLHKASEILVNEFRSGMLGRISLETPEMVSAEIILAAEEAEQKAKEKAEREEERQARARRKYAKKRQK
>NZ_CP047962.1|WP_161507023.1|1671561_1672929_-|alkaline-phosphatase
MNKTLVCTALFAALGGLSQAQASDAKNVILFIGDGMGPSVLTATRLFKVGEEGNLEIMSLPRSARIKTFSHDAQTTDSAPSMAAYTTGVKMNNEVIAMSSDTKAVAPSKDANGNKGINNCTGDNGTPVPTILELAKAAGKSVGAVTTTELTHATPAATYAHICHRDAAYAIAEQAVPGGAGFNAALGDGVDVLMGGGANHWTPYSASNKGGRADGRDLTAELGAQGYQYVTTQSDLAKIESGKVLGLFSAKSHLDYELDRVAKGAANTQPSLSEMTAKAIDLLSQNSQGYFLMVEGGRIDHALHATNAKRSLTDAVALDEAVKTALGKVDLADTLIVVTADHDHTMTINGYAAKGNPVLDLVKNSDGSTQHDVDGKPFTTLVFGNGPNRADQRPTLTSDQVMADDYLQETGVKLGSETHGGGDVMLFADGAGSGRFKGTLDNTLVFGKLKEALGL
>NZ_CP047962.1|WP_161507022.1|1670827_1671511_-|hypothetical-protein
MMRLLLSIWLLGCTLSFPLLADEAPDLAARIRYQDRITGSDGIARESVWQEKWLRVGNQVWSQRLIPLPLARAYHATHDATPGHKHFTHQMAARWVTLNDGGGLQLRYSDAWHNQLVEVPPEEYGQVAFKPDWERIRHLINPALLQEMAPLDEAAPEQARWYEKREGKQRTRILWSSRWQLPLVVESASLDGYRSYRMEVALKPLPRQLPWQQLDGYQTLDLRDFFD
>NZ_CP047962.1|WP_161507021.1|1670009_1670783_-|amino-acid-ABC-transporter-substrate-binding-protein
MLHSVYSSLTRSPMRLPVLFLLFCATLFPGHRAHAVVVIAAEIPPYVIRSQQGAPSGMAIEVLEEAARRLQEPLEIELMPLARTLSQTRHRPDVLLLPPARNAQREPLFLWIAPLLEEAFVLVSHRQHHPAPLSVKEVAGLTLGALRGSHGQSLIQPLEGMTRELVTEEVSNASKLARGRIQGWAVAWNTARYNQQRAGLPLADLVRGDTLQQSALYLAASPLFPAAEALRWRKAIEGMREDGSLARILKQYDYQTP
>NZ_CP047962.1|WP_161507032.1|1685114_1686452_+|IS4-like-element-ISAeme15-family-transposase
MSIANDLNDVVEASGDMLARLAIFADHIPDEWITAAAALSEKATIRRRRLPSDMVLWLVVGMAFFRNEPISEVARRLNICAEGLANDALLADSALSQARQRLGKQPLEWLFKQCADVWGRERYPEDHWHGLQVFAIDGALFRTQDMPELRAHFGSGNTSTNRQTPYPMLRLVTLMNVRSHVIANAAISPYRKGEIPLASEFIHSLPDKSVTLLDKGFFGADLLLRIQAEDTDRHWLIPERKGLVYTELERYGDGDRLLQMTVSPQARKKNPALPTHWQVRAVTYEVAGKEKTVFTSLPVARFSAAQVATLYHERWEIELGYRDIKSAMQHNAITLRSKKVDLVYQELWGLLLGYNLVRREASQAAVAHQRAPNEVSFKFACQFIANQMAVMAGALSPAHTPRRLAELRGCIGVMFIETRPRPSRPRAVKISKTRFPVDRNAAPLK
>NZ_CP047962.1|WP_161507033.1|1686500_1688006_-|DUF853-family-protein
MAQPLTLAYANGQPISLLPAMANRHGLITGATGTGKTVTLQVLAEGFSRLGVPVFLADVKGDLSGLGAGGTPSAKLDARLAQLGIPAPAFAASPTLFWDLFAEQGHPVRATISDMGPLLLARLLGLNDTQSGVLELVFKVADDEGLLLLDLKDLRAMVQFAGDNAKSLTTRYGNVSTASIGAILRNLLTLESVGGDHFFGEPMLDIQDLLQTDGAGHGHINVLAAGKLTQSSRLYACFLLWLLSELFEQLPEVGDPDKPVLVFFFDEAHLLFNDAPKALLEKIELVVRLIRSKGVGVYFVTQSPADIPDSVLGQLGNRVQHALRAFTPSDQKAVRIAANTLRANPAFDAAGVITELGVGEALVSLLDEKGRPSVVERAFIAPPASRIGPLSDAERQALIQGSVLHGRYETREDRESAFERLNGGAPAASDNAPQTPLEQGGGLLDALNGILFGRTGPRGGQHDGVVQTAAKSVARTLGNEVGRQLVRGVLGSLLGGSKRRR
>NZ_CP047962.1|WP_161507034.1|1688132_1688627_-|DUF2062-domain-containing-protein
MLSRWLVRIKINPDTLRQQKWFALFGERLLTPALWQGGTRALSGAVAAGLFASWIPVPMHSLVAVGLALAFSLNLPLALLAVWFNNPLTLPFMYLYAYRTGCLVLHQTPEPFHLTWSLHWLEHEAATLVPPFLLGSLLLAVLTATTGALLTLLMLQLGRLSHSH
>NZ_CP047962.1|WP_161507035.1|1688620_1689139_-|DUF2062-domain-containing-protein
MPKRLIKRWLPDQDKLKQHKHLRLFGKLLLDANLWHLNRRSAAGAFAVGLFMAWIPLPCQMLLAAGGAILCRVNLPLSVALVWLSNPVTMPPLFYGAYLVGCQLLGHPAQHIDIQFTWAWLVSVFETLAPPLLLGSLVLALLSSLLGYTLIRTFWRINTVRQWQKRKGARAC
>NZ_CP047962.1|WP_161507830.1|1689167_1691429_+|DNA-internalization-related-competence-protein-ComEC/Rec2
MDLRLLSFALGASSSLLWPWLPSTAWGGALLALAIPLAHGRHWRLLFLVLGVLWMQLNLQYRLAWLDKLETQASHIITARVQSTESSGDKPRDKFARLLLRVETLDEQPLAIAPLVRINAYQGLPPLPAGSRITLVSSLKPAHGLANEAGMDGRCLLLGKGITATGNLRRLIEVQGAAPGMRERWLAAASIAWQGLEQAPLLAALTFGEQGGITDAQWDLFRGSGLTHIIAISGQHIALVAVLGWWLGRLLGLRGAILVSLLFAAVYSWLAGFAVATERALIMVLVWSLLRWLKRDWPSHRIWLWAFVVLVLWDPFALYSAGFWLSFMAVALLLLASLLHARPGLVRLQCLLLLGLLPLQLLLFEGMAPLALLLNLLALPLFCLGIIPLALIGVLLAPLSSTLAHALFWLSDLGLTWVLWGLGLLADHLQLWWSLPGWLMPVSALLVLLWGAWHLPGGRGLLLPVGAALLLGAWPAPTPWQVRVLDVGQGLSVLVTRGERGILYDTGDRYPGGYNMAEAAILPVLNRLDVRVLDALIISHKDRDHAGNRHAMLQAMPVRRELSSFGFARSTTLCRRGQRWHWQGLDFRVLWPERPGAGRNNDSCVVQISDGRHRLLLSGDIEQEAERRLLALESKGEGDVFASTSASARFSTLASTVLVSPHHGSRTSSTPDFVAAVNPDVVIHSAGDRNQWQFPRPEVVERYQGARQWVTGQDGAILIEAGEAGLEIRPEREQGPWYRRNGHWWQSGLWPVE
>NZ_CP047962.1|WP_005331991.1|1691617_1693387_+|lipid-A-ABC-transporter-ATP-binding-protein/permease-MsbA
MQQETSQESWPVFKRLLGYVRDRKLGLVGGIIGMLGYAAVDTTFVYSIKPLIDQGLNGNDSSVLKWMPFFVLGIVALRGCAAFLSNYCMAWVGNHVVMRLQQQVFSHLMAMPMSFFDRQNTGNLLSKVTYDAGQVSSAASSTLVSLVREGATVIGLLGLMFWHSWQLSVIFLVVGPVVGVLIGLISRRFRKISRHIQQAVGDITTSTEQMLKGHKEVLMFGGQQVEDKRFYQVSNRMRQQTMKMVAADAIGSPIVQMVASVALAVFLYVATIDSVKATLTAGTFTVMVTSMMMLLKPLKSLTDVNNQFQRGITACQSLFGLLDSTPEQDTGTRTLERARGEIEFRNVTFTYPTKDTPALHNISFKVEAGKSVALVGRSGSGKSTIASLLTRFYDIEQGEILLDGVNIREYKLSELRKQYALVSQHVHLFNDSVANNIAYAAEEKYSREEIQHAARIAHADEFVRKMPEGYDTVIGENGASLSGGQRQRIAIARALLRDSPVLLLDEATSALDTESERHIQAAIDELCKARTSLVIAHRLSTIEKADEILVIDEGHIVERGNHDALMAQQGTYAQLRAIQFGNVAVSNKG
>NZ_CP047962.1|WP_005331989.1|1693386_1694382_+|tetraacyldisaccharide-4'-kinase
MLERLWYGKSGWRWALAPLALLFALVSGGRRFAYWRGWFSTYRASLPVIVVGNISVGGNGKTPVVVWLVEQLQARGWRPGVVSRGYGGKAPHYPYRLDATSTTAQAGDEPVLIARRCGCPVVVAPRRADAVRLLEQSGEVDIVITDDGLQHYALARDIELVVVDGARRFGNGCLLPMGPLREPMTRLKRVDAIICNGGTPAQGEYPMALVAAAPRRVCDDAPLEAPLTGPVDALAGIGHPPRFFATLTGLGYELAERVGYADHQAFDRDELLARFGQRPLLMTEKDAVKCRAFAPPHWWYLPVSAELPAALLDTLLQRLTPLQAPGPDHAH
>NZ_CP047962.1|WP_005331987.1|1694532_1694733_+|Trm112-family-protein
MALDIKLLDIIACPVCKGKLHYQPQSDKAAHELICRFDRLAYPLEEGIPVLLENRARHLPLEELKP
>NZ_CP047962.1|WP_005331986.1|1694729_1695479_+|3-deoxy-manno-octulosonate-cytidylyltransferase
MSFVVVIPARYASTRLPGKPLADIHGKPMVQHVVEKALQSGADRVIVATDDELVRQALRATGVEVCMTSPDHQSGTERLAEVCRHYGFAADTIIVNVQGDEPLIPPVIIRQVADNLAAATAPMATLSVPIKDAEEAFNPNAVKVVTDKDGYALYFSRASIPWDRDRFAKSHEQIGNHYQRHIGIYAYRAGFIQRYVDWAPSALEQVEALEQLRVLWYGEKIHVAQALEAPPVGVDTQTDLDKVRALLAN
>NZ_CP047962.1|WP_041206003.1|1695689_1696334_+|UvrY/SirA/GacA-family-response-regulator-transcription-factor
MINVFLVDDHELVRTGIRRILEDVRGIKVVGEAQSGETAVAFCRQHHPDVILMDMNMPGIGGLEATRKILRIRPDVRIIVLTIHSENPFPTKVMQAGAAGYLTKGAAPDEMIHAIRLVHSGQRYISPEIAQQMALSQFASADENPFKSLSERELQIMMMITKGQKVTDISEQLNLSPKTVNSYRYRLFSKLNINGDVELTHLAIRYGMLDADTL

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Crispr_ID: NZ_CP047962_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047962_3

1691460-1691583

Orphan

Consensus_repeat	Method
ATGGCAACGCTTGGTGTAATCCTGCGCTTTGGCTAG	CRISPRCasFinder

1 spacers

DinG

The CRISPR arrays of NZ_CP047962_3

>merge|NZ_CP047962|3|1691460-1691583|CRISPRCasFinder
ATGGCAACGCTTGGTGTAATCCTGCGCTTTGGCTAGGGCAATAATCCGTCATTTCCCTTTGAGGGAGGGTGAGGGAGATGGCCAGGCGATGGCAACGCTTGGTGTAATCCTGCGCTTTGGCTAG

>NZ_CP047962|3|3|1691460-1691583|CRISPRCasFinder
ATGGCAACGCTTGGTGTAATCCTGCGCTTTGGCTAG	GGCAATAATCCGTCATTTCCCTTTGAGGGAGGGTGAGGGAGATGGCCAGGCG
ATGGCAACGCTTGGTGTAATCCTGCGCTTTGGCTAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047962.1\|WP_161507033.1\|1686500_1688006_-\|DUF853-family-protein	unknown	unknown	gnl\|CDD\|283518
NZ_CP047962.1\|WP_161507028.1\|1678876_1680949_-\|ATP-dependent-DNA-helicase-DinG	DinG	COG1199_DinG_CAS-IV-A	gnl\|CDD\|236966
NZ_CP047962.1\|WP_161507029.1\|1681332_1682406_+\|porin	unknown	unknown	gnl\|CDD\|225744
NZ_CP047962.1\|WP_161507031.1\|1683706_1684897_+\|aspartate/tyrosine/aromatic-aminotransferase	unknown	unknown	gnl\|CDD\|181731
NZ_CP047962.1\|WP_161507034.1\|1688132_1688627_-\|DUF2062-domain-containing-protein	unknown	unknown	gnl\|CDD\|378263
NZ_CP047962.1\|WP_041206003.1\|1695689_1696334_+\|UvrY/SirA/GacA-family-response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|236538
NZ_CP047962.1\|WP_041206001.1\|1698592_1699147_+\|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase	unknown	unknown	gnl\|CDD\|182763
NZ_CP047962.1\|WP_161507032.1\|1685114_1686452_+\|IS4-like-element-ISAeme15-family-transposase	unknown	unknown	gnl\|CDD\|379017
NZ_CP047962.1\|WP_005331989.1\|1693386_1694382_+\|tetraacyldisaccharide-4'-kinase	unknown	unknown	gnl\|CDD\|234808
NZ_CP047962.1\|WP_161507036.1\|1699989_1701195_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271177
NZ_CP047962.1\|WP_161507030.1\|1682619_1683561_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047962.1\|WP_005331986.1\|1694729_1695479_+\|3-deoxy-manno-octulosonate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|235473
NZ_CP047962.1\|WP_161507038.1\|1701691_1702006_+\|DUF1232-domain-containing-protein	unknown	unknown	gnl\|CDD\|225876
NZ_CP047962.1\|WP_161507027.1\|1678072_1678732_-\|DUF2057-domain-containing-protein	unknown	unknown	gnl\|CDD\|378258
NZ_CP047962.1\|WP_161507037.1\|1701342_1701699_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047962.1\|WP_005331991.1\|1691617_1693387_+\|lipid-A-ABC-transporter-ATP-binding-protein/permease-MsbA	unknown	unknown	gnl\|CDD\|183016
NZ_CP047962.1\|WP_005331987.1\|1694532_1694733_+\|Trm112-family-protein	unknown	unknown	gnl\|CDD\|225391
NZ_CP047962.1\|WP_161507830.1\|1689167_1691429_+\|DNA-internalization-related-competence-protein-ComEC/Rec2	unknown	unknown	gnl\|CDD\|236924
NZ_CP047962.1\|WP_041206002.1\|1696445_1698299_+\|excinuclease-ABC-subunit-UvrC	unknown	unknown	gnl\|CDD\|234792
NZ_CP047962.1\|WP_161507035.1\|1688620_1689139_-\|DUF2062-domain-containing-protein	unknown	unknown	gnl\|CDD\|378263

Protein	Function_ID	Function_description	E-value
NZ_CP047962.1\|WP_161507033.1\|1686500_1688006_-\|DUF853-family-protein	gnl\|CDD\|283518	pfam05872, DUF853, Bacterial protein of unknown function (DUF853). This family consists of several bacterial proteins of unknown function. BMEI1370 is thought to be an ATPase.	0
NZ_CP047962.1\|WP_161507028.1\|1678876_1680949_-\|ATP-dependent-DNA-helicase-DinG	gnl\|CDD\|236966	PRK11747, dinG, ATP-dependent DNA helicase DinG; Provisional.	0
NZ_CP047962.1\|WP_161507029.1\|1681332_1682406_+\|porin	gnl\|CDD\|225744	COG3203, OmpC, Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane].	1.5091e-28
NZ_CP047962.1\|WP_161507031.1\|1683706_1684897_+\|aspartate/tyrosine/aromatic-aminotransferase	gnl\|CDD\|181731	PRK09257, PRK09257, aromatic amino acid transaminase.	0
NZ_CP047962.1\|WP_161507034.1\|1688132_1688627_-\|DUF2062-domain-containing-protein	gnl\|CDD\|378263	pfam09835, DUF2062, Uncharacterized protein conserved in bacteria (DUF2062). This domain, found in various prokaryotic proteins, has no known function.	1.01903e-27
NZ_CP047962.1\|WP_041206003.1\|1695689_1696334_+\|UvrY/SirA/GacA-family-response-regulator-transcription-factor	gnl\|CDD\|236538	PRK09483, PRK09483, response regulator; Provisional.	5.13731e-165
NZ_CP047962.1\|WP_041206001.1\|1698592_1699147_+\|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase	gnl\|CDD\|182763	PRK10832, PRK10832, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase.	1.16294e-83
NZ_CP047962.1\|WP_161507032.1\|1685114_1686452_+\|IS4-like-element-ISAeme15-family-transposase	gnl\|CDD\|379017	pfam13006, Nterm_IS4, Insertion element 4 transposase N-terminal. This family represents the N-terminal region of proteins carrying the transposase enzyme, DDE_Tnp_1 (that was Transposase_11), pfam01609, at the C-terminus. The full-length members are Insertion Element 4, IS4. Within the collection of E.coli strains, ECOR, the number of IS4 elements varies from zero to 14, with an average of 5 copies/strain.	6.94821e-32
NZ_CP047962.1\|WP_005331989.1\|1693386_1694382_+\|tetraacyldisaccharide-4'-kinase	gnl\|CDD\|234808	PRK00652, lpxK, tetraacyldisaccharide 4'-kinase; Reviewed.	2.0377e-167
NZ_CP047962.1\|WP_161507036.1\|1699989_1701195_+\|site-specific-integrase	gnl\|CDD\|271177	cd00796, INT_Rci_Hp1_C, Shufflon-specific DNA recombinase Rci and Bacteriophage Hp1_like integrase, C-terminal catalytic domain. Rci protein is a tyrosine recombinase specifically involved in Shufflon type of DNA rearrangement in bacteria. The shufflon of plasmid R64 consists of four invertible DNA segments which are separated and flanked by seven 19-bp repeat sequences. RCI recombinase facilitates the site-specific recombination between any inverted repeats results in an inversion of the DNA segment(s) either independently or in groups. HP1 integrase promotes site-specific recombination of the HP1 genome into that of Haemophilus influenza. Bacteriophage Hp1_like integrases are tyrosine based site specific recombinases. They belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	3.55503e-34
NZ_CP047962.1\|WP_161507038.1\|1701691_1702006_+\|DUF1232-domain-containing-protein	gnl\|CDD\|225876	COG3339, COG3339, Uncharacterized conserved protein [Function unknown].	3.3875e-10
NZ_CP047962.1\|WP_005331986.1\|1694729_1695479_+\|3-deoxy-manno-octulosonate-cytidylyltransferase	gnl\|CDD\|235473	PRK05450, PRK05450, 3-deoxy-manno-octulosonate cytidylyltransferase; Provisional.	2.55943e-155
NZ_CP047962.1\|WP_161507027.1\|1678072_1678732_-\|DUF2057-domain-containing-protein	gnl\|CDD\|378258	pfam09829, DUF2057, Uncharacterized protein conserved in bacteria (DUF2057). This domain, found in various prokaryotic proteins, has no known function.	1.57292e-49
NZ_CP047962.1\|WP_005331991.1\|1691617_1693387_+\|lipid-A-ABC-transporter-ATP-binding-protein/permease-MsbA	gnl\|CDD\|183016	PRK11176, PRK11176, lipid A ABC transporter ATP-binding protein/permease MsbA.	0
NZ_CP047962.1\|WP_005331987.1\|1694532_1694733_+\|Trm112-family-protein	gnl\|CDD\|225391	COG2835, COG2835, Uncharacterized conserved protein [Function unknown].	2.27803e-17
NZ_CP047962.1\|WP_161507830.1\|1689167_1691429_+\|DNA-internalization-related-competence-protein-ComEC/Rec2	gnl\|CDD\|236924	PRK11539, PRK11539, ComEC family competence protein; Provisional.	2.13937e-112
NZ_CP047962.1\|WP_041206002.1\|1696445_1698299_+\|excinuclease-ABC-subunit-UvrC	gnl\|CDD\|234792	PRK00558, uvrC, excinuclease ABC subunit UvrC.	0
NZ_CP047962.1\|WP_161507035.1\|1688620_1689139_-\|DUF2062-domain-containing-protein	gnl\|CDD\|378263	pfam09835, DUF2062, Uncharacterized protein conserved in bacteria (DUF2062). This domain, found in various prokaryotic proteins, has no known function.	3.58597e-47

>NZ_CP047962.1|WP_161507830.1|1689167_1691429_+|DNA-internalization-related-competence-protein-ComEC/Rec2
MDLRLLSFALGASSSLLWPWLPSTAWGGALLALAIPLAHGRHWRLLFLVLGVLWMQLNLQYRLAWLDKLETQASHIITARVQSTESSGDKPRDKFARLLLRVETLDEQPLAIAPLVRINAYQGLPPLPAGSRITLVSSLKPAHGLANEAGMDGRCLLLGKGITATGNLRRLIEVQGAAPGMRERWLAAASIAWQGLEQAPLLAALTFGEQGGITDAQWDLFRGSGLTHIIAISGQHIALVAVLGWWLGRLLGLRGAILVSLLFAAVYSWLAGFAVATERALIMVLVWSLLRWLKRDWPSHRIWLWAFVVLVLWDPFALYSAGFWLSFMAVALLLLASLLHARPGLVRLQCLLLLGLLPLQLLLFEGMAPLALLLNLLALPLFCLGIIPLALIGVLLAPLSSTLAHALFWLSDLGLTWVLWGLGLLADHLQLWWSLPGWLMPVSALLVLLWGAWHLPGGRGLLLPVGAALLLGAWPAPTPWQVRVLDVGQGLSVLVTRGERGILYDTGDRYPGGYNMAEAAILPVLNRLDVRVLDALIISHKDRDHAGNRHAMLQAMPVRRELSSFGFARSTTLCRRGQRWHWQGLDFRVLWPERPGAGRNNDSCVVQISDGRHRLLLSGDIEQEAERRLLALESKGEGDVFASTSASARFSTLASTVLVSPHHGSRTSSTPDFVAAVNPDVVIHSAGDRNQWQFPRPEVVERYQGARQWVTGQDGAILIEAGEAGLEIRPEREQGPWYRRNGHWWQSGLWPVE
>NZ_CP047962.1|WP_161507035.1|1688620_1689139_-|DUF2062-domain-containing-protein
MPKRLIKRWLPDQDKLKQHKHLRLFGKLLLDANLWHLNRRSAAGAFAVGLFMAWIPLPCQMLLAAGGAILCRVNLPLSVALVWLSNPVTMPPLFYGAYLVGCQLLGHPAQHIDIQFTWAWLVSVFETLAPPLLLGSLVLALLSSLLGYTLIRTFWRINTVRQWQKRKGARAC
>NZ_CP047962.1|WP_161507034.1|1688132_1688627_-|DUF2062-domain-containing-protein
MLSRWLVRIKINPDTLRQQKWFALFGERLLTPALWQGGTRALSGAVAAGLFASWIPVPMHSLVAVGLALAFSLNLPLALLAVWFNNPLTLPFMYLYAYRTGCLVLHQTPEPFHLTWSLHWLEHEAATLVPPFLLGSLLLAVLTATTGALLTLLMLQLGRLSHSH
>NZ_CP047962.1|WP_161507033.1|1686500_1688006_-|DUF853-family-protein
MAQPLTLAYANGQPISLLPAMANRHGLITGATGTGKTVTLQVLAEGFSRLGVPVFLADVKGDLSGLGAGGTPSAKLDARLAQLGIPAPAFAASPTLFWDLFAEQGHPVRATISDMGPLLLARLLGLNDTQSGVLELVFKVADDEGLLLLDLKDLRAMVQFAGDNAKSLTTRYGNVSTASIGAILRNLLTLESVGGDHFFGEPMLDIQDLLQTDGAGHGHINVLAAGKLTQSSRLYACFLLWLLSELFEQLPEVGDPDKPVLVFFFDEAHLLFNDAPKALLEKIELVVRLIRSKGVGVYFVTQSPADIPDSVLGQLGNRVQHALRAFTPSDQKAVRIAANTLRANPAFDAAGVITELGVGEALVSLLDEKGRPSVVERAFIAPPASRIGPLSDAERQALIQGSVLHGRYETREDRESAFERLNGGAPAASDNAPQTPLEQGGGLLDALNGILFGRTGPRGGQHDGVVQTAAKSVARTLGNEVGRQLVRGVLGSLLGGSKRRR
>NZ_CP047962.1|WP_161507032.1|1685114_1686452_+|IS4-like-element-ISAeme15-family-transposase
MSIANDLNDVVEASGDMLARLAIFADHIPDEWITAAAALSEKATIRRRRLPSDMVLWLVVGMAFFRNEPISEVARRLNICAEGLANDALLADSALSQARQRLGKQPLEWLFKQCADVWGRERYPEDHWHGLQVFAIDGALFRTQDMPELRAHFGSGNTSTNRQTPYPMLRLVTLMNVRSHVIANAAISPYRKGEIPLASEFIHSLPDKSVTLLDKGFFGADLLLRIQAEDTDRHWLIPERKGLVYTELERYGDGDRLLQMTVSPQARKKNPALPTHWQVRAVTYEVAGKEKTVFTSLPVARFSAAQVATLYHERWEIELGYRDIKSAMQHNAITLRSKKVDLVYQELWGLLLGYNLVRREASQAAVAHQRAPNEVSFKFACQFIANQMAVMAGALSPAHTPRRLAELRGCIGVMFIETRPRPSRPRAVKISKTRFPVDRNAAPLK
>NZ_CP047962.1|WP_161507031.1|1683706_1684897_+|aspartate/tyrosine/aromatic-aminotransferase
MFEKVVAAPADPILGLTEAFRADSRSHKINLGVGIYKDETGATPILHCVKKAEQKLLTDEKTKNYLGIEGNIEYGRIVQQLLFGQDSALVASGRAKTAQAPGGTGALRIAAEFVVRNGLAKTIWISDPTWANHVSVFQAAGLTVKWYKYYDAATKGLDFAAMQASLAEAQAGDLVLLHGCCHNPTGIDPTADQWRALAKQSAAAGWLPLFDFAYQGFARGIEEDAEGLRIFAECHDELLVASSFSKNFGLYNERVGAFTLVSATKAIADVAFTQVKTVIRANYSNPPSHGAAVVTTIVSDPALYAEWVEEVAAMRVRIREMRELLVEKLAALGVSQDFSFIREQNGMFSFSGLSKDQVERLKSEFAIYIVGSGRISVAGITRANIDPLCDAIAKVL
>NZ_CP047962.1|WP_161507030.1|1682619_1683561_+|hypothetical-protein
MIDFSHPEWRALAQQLLGHSPVVIRGRQWQPLVGLLKDNQLLLAHGSNSYELTPAGRRYLTRELMLAEIATALPEPEEWLHAQGWQLGEQVNERVLAALYRKSDVNFTPNEQIDFEDKGIRLCADQLLRLRSAQPFSLFFSSGTLIDAAPWLQALGEVALPERTLAGLGKILWGEGNIERVITTDSVGAFAELLLESGCLLVWAPPSASLALQQVVAALPPNVLWSHLTALDPAGVDRVQALAQRLGRPASWWLPRDLAPIKEAYAAPLQDARPWEPSRIPRPLRAWCSDLVESNRGLSAEVCALASGWHAIG
>NZ_CP047962.1|WP_161507029.1|1681332_1682406_+|porin
MKKTILAIAIPALFASAANAAVIYDKDGTTFDIYGRVHAQYFGEYDSYDADAESYSKNDGELTTYARLGWSGKMALNDTWSGVAKTEWQLASENSYGSDKRELKARHIYAGFDGSQYGQFLFGQTETAFYNATVAKTDIFNDYGDMANVYDGCQEGQAIYNGQWNGFGLKGGYITNNGSYDANYAGWSGVEGKMDHGYTLGATYDFDFGLGLAAGYESKSFEDASTLTITSENGTFSRADLTDKNDWAVAASYTYQGFYFAALYNESTYKFDGFNDAKARGYELAASYNVDAWTFLAGYNFAEAKVEGVTSYEDTVDFTSMGVEYAFNSKLKAYTEYKIQGLSQQDDEWTVGMQYNF
>NZ_CP047962.1|WP_161507028.1|1678876_1680949_-|ATP-dependent-DNA-helicase-DinG
MLSTRLKATIRNTYRQIADGLPGFVPRKEQNFLVAEIAKTLTGEYEKSRRILVAEAGTGIGKSLSYAQGAIPVARLTQKKLVISTATVALQEQLIHKDLPFYHRHSELPFRFMLVKGRQRYCCEHLLEQAASGAEMANFELDFGSLSKHKPSDSDKERYQALWQAYTEGKWDGDRDNWPKPIPDLCWDRIAADRHSCNKALSHHQHCPFHRARNDMDAADVLVVNHALLLSDLTMGGGIILPPPDECIYVLDEAHHLPTIARDHGAASASIKGSRRWLEKLVQSAGKLARALNKESLIDPQLKLQDALASMQPDLKALEQWLAGNDHLFGSEQHHRFAEGVLPDPLPMLAENLKEASKKALRALDRMQGAIGEALKDGEIRRKEAEPLLAESGFHLQRLESFCALWEMLSRHVPTGKTPLARWMARSEDGDIWLHASPIEVGYLLEEWLWSRCLGAVLVSATLTALSSFSYFRHQVGLKEHDGTRYLRLRSPFEYHKAELYLPKMTHEPSAPGFTQELVDTLPRLLAGKEASLVLFSSYRQMNEVAVGLRAKGLSLLVQGEASRNALLTLHKQKCDGGQASILFGTGSFSEGLDLPGHYLTNLVITKLPFAVPNSPVEEATAEWVEKRGGNPFLQLTVPEASRKLIQACGRLIRKEADRGRVTILDRRLLTKRYGKGLLDALPPFTRRIE
>NZ_CP047962.1|WP_161507027.1|1678072_1678732_-|DUF2057-domain-containing-protein
MKLTVLVPALAGLLWAGSALADSQLEIHNPYVVQLIDGESINPKLLEKTSSFPISAGKHQVVVAFEGNYSNRNDIKLVTAEPLVINFTAGDNQTLMLDFKKPRNEDEAKAFVKEQKVVLKDRVSGQALASEQFVMPKVGGFQLTRDYQQELLKMGKAFNQPATVAVSSAAVMAAASAPVEVAPSKAQSNPEALTQLQSWYNKADAETRKAFQIWVIQQQ
>NZ_CP047962.1|WP_005331991.1|1691617_1693387_+|lipid-A-ABC-transporter-ATP-binding-protein/permease-MsbA
MQQETSQESWPVFKRLLGYVRDRKLGLVGGIIGMLGYAAVDTTFVYSIKPLIDQGLNGNDSSVLKWMPFFVLGIVALRGCAAFLSNYCMAWVGNHVVMRLQQQVFSHLMAMPMSFFDRQNTGNLLSKVTYDAGQVSSAASSTLVSLVREGATVIGLLGLMFWHSWQLSVIFLVVGPVVGVLIGLISRRFRKISRHIQQAVGDITTSTEQMLKGHKEVLMFGGQQVEDKRFYQVSNRMRQQTMKMVAADAIGSPIVQMVASVALAVFLYVATIDSVKATLTAGTFTVMVTSMMMLLKPLKSLTDVNNQFQRGITACQSLFGLLDSTPEQDTGTRTLERARGEIEFRNVTFTYPTKDTPALHNISFKVEAGKSVALVGRSGSGKSTIASLLTRFYDIEQGEILLDGVNIREYKLSELRKQYALVSQHVHLFNDSVANNIAYAAEEKYSREEIQHAARIAHADEFVRKMPEGYDTVIGENGASLSGGQRQRIAIARALLRDSPVLLLDEATSALDTESERHIQAAIDELCKARTSLVIAHRLSTIEKADEILVIDEGHIVERGNHDALMAQQGTYAQLRAIQFGNVAVSNKG
>NZ_CP047962.1|WP_005331989.1|1693386_1694382_+|tetraacyldisaccharide-4'-kinase
MLERLWYGKSGWRWALAPLALLFALVSGGRRFAYWRGWFSTYRASLPVIVVGNISVGGNGKTPVVVWLVEQLQARGWRPGVVSRGYGGKAPHYPYRLDATSTTAQAGDEPVLIARRCGCPVVVAPRRADAVRLLEQSGEVDIVITDDGLQHYALARDIELVVVDGARRFGNGCLLPMGPLREPMTRLKRVDAIICNGGTPAQGEYPMALVAAAPRRVCDDAPLEAPLTGPVDALAGIGHPPRFFATLTGLGYELAERVGYADHQAFDRDELLARFGQRPLLMTEKDAVKCRAFAPPHWWYLPVSAELPAALLDTLLQRLTPLQAPGPDHAH
>NZ_CP047962.1|WP_005331987.1|1694532_1694733_+|Trm112-family-protein
MALDIKLLDIIACPVCKGKLHYQPQSDKAAHELICRFDRLAYPLEEGIPVLLENRARHLPLEELKP
>NZ_CP047962.1|WP_005331986.1|1694729_1695479_+|3-deoxy-manno-octulosonate-cytidylyltransferase
MSFVVVIPARYASTRLPGKPLADIHGKPMVQHVVEKALQSGADRVIVATDDELVRQALRATGVEVCMTSPDHQSGTERLAEVCRHYGFAADTIIVNVQGDEPLIPPVIIRQVADNLAAATAPMATLSVPIKDAEEAFNPNAVKVVTDKDGYALYFSRASIPWDRDRFAKSHEQIGNHYQRHIGIYAYRAGFIQRYVDWAPSALEQVEALEQLRVLWYGEKIHVAQALEAPPVGVDTQTDLDKVRALLAN
>NZ_CP047962.1|WP_041206003.1|1695689_1696334_+|UvrY/SirA/GacA-family-response-regulator-transcription-factor
MINVFLVDDHELVRTGIRRILEDVRGIKVVGEAQSGETAVAFCRQHHPDVILMDMNMPGIGGLEATRKILRIRPDVRIIVLTIHSENPFPTKVMQAGAAGYLTKGAAPDEMIHAIRLVHSGQRYISPEIAQQMALSQFASADENPFKSLSERELQIMMMITKGQKVTDISEQLNLSPKTVNSYRYRLFSKLNINGDVELTHLAIRYGMLDADTL
>NZ_CP047962.1|WP_041206002.1|1696445_1698299_+|excinuclease-ABC-subunit-UvrC
MTFSSEPHFDSKAFLSAVTHQSGVYRMYDGGGTVIYVGKAKDLKKRLASYFRPNVDSIKTRTLVRQIADIQVTVTHTETEALILEHNLIKQYQPRYNVLLRDDKSYPWIIITAHQHPRIGVHRGARKIKGEYFGPYPSGGAVRESLHLMQKIFPVRQCEDAVYANRSRPCLLYQLKRCAGPCVAGLVSEAEYAQQVELAKLFLAGKNQQVIGELVGKMESASGDLRFEEAARYRDQIQALRRVTEQQSVSGNVLDELDVVGVAFEQGTACIHVLFIRQGKVLGSRSYFPKVPADTPLDEVVQSFLLQFYLSGQGGRQIPSEVLLDVALEDESVIAQTLSQTAGYKVRVQSRTRAERARFIKLASINAQTALRSRLAHKSTITARYDQLEELLELERPIARMECFDISHTMGERTVASCVVFNREGPLSSEYRRFNIDGITGGDDYAAMEQVLERRFGKQQEPDKVPDVLFIDGGLGQLRRAEEILARQLEFLGGKYPLLVGIAKGVTRKAGLETLILGESHEELHLPADMPALHLIQHIRDESHRFAITGHRARRAKARTTSTLEDIPGVGPKRRQALLKYLGGLQEVKKAGVDELAKVPGISQELAQSIHDALHSL
>NZ_CP047962.1|WP_041206001.1|1698592_1699147_+|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase
MTNIPNLLTFFRILLIPVFVILFYLPYQWSYLAAALVFILAAATDWFDGYLARKLNQSTAFGAFLDPVADKIMVAAALVVIVEHYNTIWVTIPAMTMIGREIIISALREWMAELGKRSSVAVSWIGKWKTMIQMVSLTGLIWQYDIWMVWLSYVLLYVATVLTFWSMFQYMKAAWGDLTYHSRF
>NZ_CP047962.1|WP_161507036.1|1699989_1701195_+|site-specific-integrase
MQTKFRFTNAAIKALPAQQRDAGATELEFSDTEVIGLKLLSGKSQGSKRFLLRYTLQGKKRSIALGRFGDIDVSQARTIARKHKAMLAEGIDPVAERDSYKTEPTLSEFFWQTFLPHLKTIGKRSINSDIQRFKHNIEPRFGAMRYRQLKAMDVLQLQSEMVHPNNPQQTAYAPSTANRVLAQLKTMGSYAVRWGILDTNEAAKIKLLKEDNARTRFLSIEEMKRVIEVALQDRNQAAGSFIAMLYLTGARKSEVLLAKWEHVNWEDKTLFVPLTKNGKSRIIYLSALAIDILEKLPRIAGNPYVFASQHIRCQGKPIGEPRCAYERVLQKAGIEDRDEVCFHTARHSVASALVSSGQYSLYDVKAQLAHASIQSSQRYAKLTSERSRNISEGLSSMIQAE
>NZ_CP047962.1|WP_161507037.1|1701342_1701699_+|hypothetical-protein
MEWPEETLLAAYPALHVSVMEQIIEPFSSQEEARAFWDATGCCLIIIEMTDSMSEFQTMPQHTQNQVMFGLRYPEQEFAISEDWRLLLAILNDEGAGIYLLIHSDAPLLPTLEAMHHE
>NZ_CP047962.1|WP_161507038.1|1701691_1702006_+|DUF1232-domain-containing-protein
MSNPSHSDIMRKLKDIKGIKELLEKAVLLYVLLTDGDLPVWCYALIIGALAYLVNPFDVVPDPIPFAGYLDDLSVITSALGKVRTSIPRTKNENFSHLISMGYQ

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Crispr_ID: NZ_CP047962_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047962_4

3102605-3102744

TypeV-U4

Consensus_repeat	Method
TCAGCCTCCGGTCGTTACTGGAAGGAGAGGGAAGAAGGCGGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP047962_4

>merge|NZ_CP047962|4|3102605-3102744|CRISPRCasFinder
TCAGCCTCCGGTCGTTACTGGAAGGAGAGGGAAGAAGGCGGCCTCATGCCAGTCCCACAGCGCCGTTGTGCGATCCACGGTCGTTATCTCGCTCATTCTCAGCCTCCGGTCGTTACTGGAAGGAGAGGGAAGAAGGCGGC

>NZ_CP047962|4|4|3102605-3102744|CRISPRCasFinder
TCAGCCTCCGGTCGTTACTGGAAGGAGAGGGAAGAAGGCGGC	CTCATGCCAGTCCCACAGCGCCGTTGTGCGATCCACGGTCGTTATCTCGCTCATTC
TCAGCCTCCGGTCGTTACTGGAAGGAGAGGGAAGAAGGCGGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047962.1\|WP_041207033.1\|3103618_3104146_-\|molybdenum-cofactor-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|131715
NZ_CP047962.1\|WP_041206129.1\|3109959_3110469_-\|ferredoxin-type-protein-NapF	unknown	unknown	gnl\|CDD\|319886
NZ_CP047962.1\|WP_041206124.1\|3104969_3105425_-\|nitrate-reductase-cytochrome-c-type-subunit	unknown	unknown	gnl\|CDD\|367715
NZ_CP047962.1\|WP_005325506.1\|3102115_3102601_-\|molybdopterin-synthase-catalytic-subunit-MoaE	unknown	unknown	gnl\|CDD\|182642
NZ_CP047962.1\|WP_041206126.1\|3105424_3106300_-\|quinol-dehydrogenase-ferredoxin-subunit-NapH	unknown	unknown	gnl\|CDD\|236535
NZ_CP047962.1\|WP_005325498.1\|3095551_3096208_-\|GTP-cyclohydrolase-I-FolE	unknown	unknown	gnl\|CDD\|236472
NZ_CP047962.1\|WP_004575061.1\|3092172_3093510_-\|IS4-like-element-ISAeme15-family-transposase	unknown	unknown	gnl\|CDD\|379017
NZ_CP047962.1\|WP_005325496.1\|3093632_3095282_-\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|223910
NZ_CP047962.1\|WP_005325503.1\|3099460_3100516_-\|molybdenum-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|131197
NZ_CP047962.1\|WP_005325505.1\|3101302_3102031_-\|molybdate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270257
NZ_CP047962.1\|WP_041206127.1\|3107044_3109534_-\|nitrate-reductase-catalytic-subunit-NapA	unknown	unknown	gnl\|CDD\|237416
NZ_CP047962.1\|WP_005325504.1\|3100512_3101193_-\|molybdate-ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|226629
NZ_CP047962.1\|WP_005325513.1\|3104367_3104958_-\|cytochrome-c3-family-protein	unknown	unknown	gnl\|CDD\|131216
NZ_CP047962.1\|WP_041207032.1\|3096566_3097793_+\|molybdopterin-molybdotransferase-MoeA	unknown	unknown	gnl\|CDD\|182643
NZ_CP047962.1\|WP_041204444.1\|3109660_3109927_-\|chaperone-NapD	unknown	unknown	gnl\|CDD\|367731
NZ_CP047962.1\|WP_005325507.1\|3102800_3103046_-\|molybdopterin-synthase-sulfur-carrier-subunit	unknown	unknown	gnl\|CDD\|182985
NZ_CP047962.1\|WP_005325501.1\|3097789_3098545_+\|molybdopterin-synthase-adenylyltransferase-MoeB	unknown	unknown	gnl\|CDD\|180204
NZ_CP047962.1\|WP_005325509.1\|3103042_3103537_-\|cyclic-pyranopterin-monophosphate-synthase-MoaC	unknown	unknown	gnl\|CDD\|236483
NZ_CP047962.1\|WP_041206121.1\|3098610_3099390_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|211851
NZ_CP047962.1\|WP_005325518.1\|3106296_3107031_-\|ferredoxin-type-protein-NapG	unknown	unknown	gnl\|CDD\|236534

Protein	Function_ID	Function_description	E-value
NZ_CP047962.1\|WP_041207033.1\|3103618_3104146_-\|molybdenum-cofactor-biosynthesis-protein-B	gnl\|CDD\|131715	TIGR02667, Molybdenum_cofactor_biosynthesis_protein_B., molybdenum cofactor biosynthesis protein B, proteobacterial. This model represents the MoaB protein molybdopterin biosynthesis regions in Proteobacteria. This crystallized but incompletely characterized protein is thought to be involved in, though not required for, early steps in molybdopterin biosynthesis. It may bind a molybdopterin precursor. A distinctive conserved motif PCN near the C-terminus helps distinguish this clade from other homologs, including sets of proteins designated MogA. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	1.73657e-91
NZ_CP047962.1\|WP_041206129.1\|3109959_3110469_-\|ferredoxin-type-protein-NapF	gnl\|CDD\|319886	cd10564, NapF_like, NapF, iron-sulfur subunit of periplasmic nitrate reductase. This family contains NapF protein, the iron-sulfur subunit of periplasmic nitrate reductase. The periplasmic nitrate reductase NapABC of Escherichia coli likely functions during anaerobic growth in low-nitrate environments; napF operon expression is activated by cyclic AMP receptor protein (Crp). NapF is a subfamily of the beta subunit of DMSO reductase (DMSOR) family. DMSOR family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.	8.05609e-64
NZ_CP047962.1\|WP_041206124.1\|3104969_3105425_-\|nitrate-reductase-cytochrome-c-type-subunit	gnl\|CDD\|367715	pfam03892, NapB, Nitrate reductase cytochrome c-type subunit (NapB). The napB gene encodes a dihaem cytochrome c, the small subunit of a heterodimeric periplasmic nitrate reductase.	2.73122e-65
NZ_CP047962.1\|WP_005325506.1\|3102115_3102601_-\|molybdopterin-synthase-catalytic-subunit-MoaE	gnl\|CDD\|182642	PRK10678, moaE, molybdopterin synthase catalytic subunit MoaE.	4.67389e-78
NZ_CP047962.1\|WP_041206126.1\|3105424_3106300_-\|quinol-dehydrogenase-ferredoxin-subunit-NapH	gnl\|CDD\|236535	PRK09477, napH, quinol dehydrogenase membrane component; Provisional.	2.47826e-151
NZ_CP047962.1\|WP_005325498.1\|3095551_3096208_-\|GTP-cyclohydrolase-I-FolE	gnl\|CDD\|236472	PRK09347, folE, GTP cyclohydrolase I; Provisional.	5.15544e-104
NZ_CP047962.1\|WP_004575061.1\|3092172_3093510_-\|IS4-like-element-ISAeme15-family-transposase	gnl\|CDD\|379017	pfam13006, Nterm_IS4, Insertion element 4 transposase N-terminal. This family represents the N-terminal region of proteins carrying the transposase enzyme, DDE_Tnp_1 (that was Transposase_11), pfam01609, at the C-terminus. The full-length members are Insertion Element 4, IS4. Within the collection of E.coli strains, ECOR, the number of IS4 elements varies from zero to 14, with an average of 5 copies/strain.	6.46165e-32
NZ_CP047962.1\|WP_005325496.1\|3093632_3095282_-\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	1.01719e-71
NZ_CP047962.1\|WP_005325503.1\|3099460_3100516_-\|molybdenum-ABC-transporter-ATP-binding-protein	gnl\|CDD\|131197	TIGR02142, Molybdenum_import_ATP-binding_protein_ModC, molybdenum ABC transporter, ATP-binding protein. This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions].	2.8742e-92
NZ_CP047962.1\|WP_005325505.1\|3101302_3102031_-\|molybdate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270257	cd13539, PBP2_AvModA, Substrate binding domain of ModA/WtpA from Azotobacter vinelandii and its closest homologs;the type 2 periplasmic binding protein fold. This subfamily contains domains found in ModA proteins that serve as initial receptors in the ABC transport of molybdate in eubacteria and archaea. Bacteria and archaea import molybdenum and tungsten from the environment in the form of the oxyanions molybdate (MoO(4) (2-)) and tungstate (WO(4) (2-)). After binding molybdate with high affinity, they interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. In contrast to the structure of the two ModA homologs from Escherichia coli and Azotobacter vinelandii, where the oxygen atoms are tetrahedrally arranged around the metal center, the structure of Pyrococcus furiosus ModA/WtpA (PfModA) has shown that a binding site for molybdate and tungstate is where the central metal atom is in a hexacoordinate configuration. This octahedral geometry was rather unexpected. The ModA proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	2.22627e-76
NZ_CP047962.1\|WP_041206127.1\|3107044_3109534_-\|nitrate-reductase-catalytic-subunit-NapA	gnl\|CDD\|237416	PRK13532, PRK13532, nitrate reductase catalytic subunit NapA.	0
NZ_CP047962.1\|WP_005325504.1\|3100512_3101193_-\|molybdate-ABC-transporter-permease-subunit	gnl\|CDD\|226629	COG4149, ModC, ABC-type molybdate transport system, permease component [Inorganic ion transport and metabolism].	2.83186e-76
NZ_CP047962.1\|WP_005325513.1\|3104367_3104958_-\|cytochrome-c3-family-protein	gnl\|CDD\|131216	TIGR02161, Cytochrome_c-type_protein_NapC, periplasmic nitrate (or nitrite) reductase c-type cytochrome, NapC/NirT family. Nearly every member of this subfamily is NapC, a predicted membrane-anchored four-heme c-type cytochrome that forms one component of the periplasmic nitrate reductase along with NapA, NapB, NapD, NapE, and NapF subunits. A single known exception at this time is NirT, which is instead a component of a nitrite reductase. This family excludes TorC subunits of trimethylamine N-oxide (TMAO) reductases.	8.30223e-122
NZ_CP047962.1\|WP_041207032.1\|3096566_3097793_+\|molybdopterin-molybdotransferase-MoeA	gnl\|CDD\|182643	PRK10680, PRK10680, molybdopterin biosynthesis protein MoeA; Provisional.	0
NZ_CP047962.1\|WP_041204444.1\|3109660_3109927_-\|chaperone-NapD	gnl\|CDD\|367731	pfam03927, NapD, NapD protein. Uncharacterized protein involved in formation of periplasmic nitrate reductase.	1.25276e-26
NZ_CP047962.1\|WP_005325507.1\|3102800_3103046_-\|molybdopterin-synthase-sulfur-carrier-subunit	gnl\|CDD\|182985	PRK11130, moaD, molybdopterin synthase small subunit; Provisional.	2.76853e-54
NZ_CP047962.1\|WP_005325501.1\|3097789_3098545_+\|molybdopterin-synthase-adenylyltransferase-MoeB	gnl\|CDD\|180204	PRK05690, PRK05690, molybdopterin biosynthesis protein MoeB; Provisional.	9.34517e-158
NZ_CP047962.1\|WP_005325509.1\|3103042_3103537_-\|cyclic-pyranopterin-monophosphate-synthase-MoaC	gnl\|CDD\|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	4.71655e-101
NZ_CP047962.1\|WP_041206121.1\|3098610_3099390_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|211851	TIGR03611, RutD, pyrimidine utilization protein D. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the hydrolase, alpha/beta fold family defined by pfam00067.	2.23931e-22
NZ_CP047962.1\|WP_005325518.1\|3106296_3107031_-\|ferredoxin-type-protein-NapG	gnl\|CDD\|236534	PRK09476, napG, quinol dehydrogenase periplasmic component; Provisional.	7.42628e-153

>NZ_CP047962.1|WP_005325506.1|3102115_3102601_-|molybdopterin-synthase-catalytic-subunit-MoaE
MSQATTTPTDRILVQRADFSLGEEYERLATRHDSGAIVTFVGKVRDFNQGDAVKGLSLEHYPGMTEKALVDIVNQARARWPLQECTLIHRIGDLLLGDQIVLVAVSSAHREAAFEACHFIMDFLKTRAPFWKKELTAEGIQRWVEAKQSDDAAAARWRQDP
>NZ_CP047962.1|WP_005325505.1|3101302_3102031_-|molybdate-ABC-transporter-substrate-binding-protein
MKKQLSVVLLGLVAGALYSGAAQADEVKVAVAANFKGTMERIGKAFTAKTGHRVVISSAATGVLYTQITHGAPFDIFLSADVATPQKLEAEGKGSDRFTYAIGQLGLWKKGGPAPDETTLRSWKGNLAIANPKTAPYGTAAMATLARLKIDPKQYRVLTGTNISQTWQFVDTGNAELGFVAWANLVEAGKTGEAWAVPASFYPPIEQQGLILKKGAAVEALVAWLKGPGQEQIKAAGYALPQ
>NZ_CP047962.1|WP_005325504.1|3100512_3101193_-|molybdate-ABC-transporter-permease-subunit
MSEGDLQAVWLTLKLAASTTAILLLLSPPLAWWLSRSQHRLRPLVEALVALPLVLPPTVLGFYLLLAFSPEYGLGAWWRETFGTPLAFSFLGLLFASILYSLPFVVQPLTSAFVNMGNKEIEAAATLGLGPLERFFQIILPMTLPSFVMAAALGFAHTLGEFGVVLMIGGNIPGETQVLSIALFDHVEAMDYQHAHYLAGGLMGFSLVMLVLVYGVLQRRQRRLFG
>NZ_CP047962.1|WP_005325503.1|3099460_3100516_-|molybdenum-ABC-transporter-ATP-binding-protein
MSLHLKAWRRFGGFELDCDLTLPLGGILGLFGPSGCGKSTLLRIIAGLDRAPSDVLHWQGRDLAALLPEARRIGLVFQDSRLFPHMTVLGNLQLAAGKGRGRWQHEALAMRLGFADLLGQPAHGLSGGQRQRVALGRALLAEPDLLLLDEPFSALDSRSRIHQAHVLKGLQRESGIPMIFVSHAMEEVSLLCDQLVLQEGGRVEAQGRPSEIFARTDLSLASRDDAGVMLTATLAHYDDAEQMATLQLGDQTLMVTMEHAPDETGELQIKVAGRDLVIATAPIVHSSLSNCLETRLLEAREVRPGQTLLQLALGQQILLARITSRSAQRLALVPGQRLYAYIKAVSLVGEG
>NZ_CP047962.1|WP_041206121.1|3098610_3099390_-|alpha/beta-fold-hydrolase
MRRNQVMKSHGLALRSAGEGPLLLLLHGLGSSSLDWQAQIEHFSQHYRVVALDLRGHGQSMQEGPFDVPTLAADVARWLEEQPEPAWVVGLSLGAMVALELALRLPHKVRGLVLVNGFSEFLLETPREQERHAMRLKWLRWFGMRPLAWWLGRELFPGPELAQVRHTFRLRFVRSNKKKTYKALLEALPGWSVRARLGSLWQPVAIISTSHDYLPLAKRVEQFASLPNASIHTPEGHHAWPAEDPAGFNHLLQRILATH
>NZ_CP047962.1|WP_005325501.1|3097789_3098545_+|molybdopterin-synthase-adenylyltransferase-MoeB
MSEILSDAELLRYNRQIILKSFDFEGQEALKQARVLVIGAGGLGCAASQYLAVAGVGRLTLVDFDRVELSNLQRQVLHSDERIGMYKVDSAAQSLRALNPWLEVETHALLADEALLDALLPGHQLVLDCTDNVTIRNLLNQRARQHRVPLVSGAAIRLEGQLCSFTWQEDEPCYACLSALFGEQALTCVEAGVLAPVVGLVGSLQALEAIKLLAGMGKSHHGRLLMIDGLSSRFRELKLPKRPDCPVCSQP
>NZ_CP047962.1|WP_041207032.1|3096566_3097793_+|molybdopterin-molybdotransferase-MoeA
MGFDTGALLPLDKALQGMLEQLTCCCETEQLPLPQALDRILAEEISSPLSVPPFDNAAMDGYAVRLADLAAGAPLPVAGKAFAGQPYEGEWPAGHCIRIMTGAPVPAGTEAVVMQEETQEGGNGITFLTTPFLGQNIRRRGEDMAQGSRVLASGLRLSPRELPLLASLGIATVTVRRPLKVAIFSTGDELKPLGTPLAHGDIYDSNRYGVKAMLTRMGIACLDLGIIPDDPAALRAAFIQADREADALITTGGVSVGEADFTKQLLEELGEIGFWKLAIKPGKPFAFGRLPNVWFFGLPGNPVSAMVTFDQLVQPALARLAGHHFARPLPLQAIATEPLKKAPGRLDFQRGMLSQGPNGLEVRSTGSQDSGVFSSLSRANCYIVLEQERGKVAAGETVTVEPFSGLLL
>NZ_CP047962.1|WP_005325498.1|3095551_3096208_-|GTP-cyclohydrolase-I-FolE
MTSLSQEALLVRAALEAQGLETPLVANELNGQQKKEKIEGHMRAIMETLGLDLADDSLAETPHRIAKMYVNEIFSGLDYATFPKVTVIENKMKVDEMIMVRDISLTSTCEHHFVTIDGLAHVAYIPRGKVIGLSKINRIVQFFARRPQVQERLTQQILLALQTLLGTKDVAISIKATHFCVKARGVMDSTSYTTTTSLGGVFKTQPDTRAEFLGGLKG
>NZ_CP047962.1|WP_005325496.1|3093632_3095282_-|methyl-accepting-chemotaxis-protein
MNTMTIGKKLSAGFAVLGLMMAFIGGFSLLEFSTMNRAAIGFTDSILPAVVRTSTLGETINAVRRYELDVFLVADDPQQQAHYRNESEKSLQEAARQITAHDGTIWAEDLEERRTFDIVKADWEKYLGLHQRIRQMQDSGQMAEAQHLFMGEGVTLYTNLAKSVGDLVRINHGYADASRKVVVAAYDSAKLSVTLSLLVGLVLVVCLSVVLTRQIRDPLIMLARQAQRIASGDLGKSELQEWIRTSRFNRDELGQLGSAIDRMQGALASLVSEIAGSVSQLSSAVEEVSAISEQSAKGMASQQSEVSQVATAMNEMQSTVNEVARNTTDAMSAAKEASRTSTQGNQVVRSAIGSIEQVSQQIEQAGTVVSQLEADSASISMVLDVIRGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAQRTQASTAEISKMIALLQERTAEAGNAMQLSRQQMQESVGLAREAGGSIDSINGAVTQISDMNTLIATATEEQNAVTEELNRSIVNIHNAADENAQGAQQTAQACVELSKLANSLHQMTQRFTL
>NZ_CP047962.1|WP_004575061.1|3092172_3093510_-|IS4-like-element-ISAeme15-family-transposase
MSIANDLNDVVEASGDMLARLAIFADHIPDEWITAAAALSEKATIRRRRLPSDMVLWLVVGMAFFRNEPISEVARRLNICAEGLANDALLADSALSQARQRLGKQPLEWLFKQCADVWGRERYPEDHWHGLQVFAIDGALFRTQDMPELRAHFGSGNTSTNRQTPYPMLRLVTLMNVRSHVIANAAISPYRKGEIPLASEFIHSLPDKSVTLLDKGFFGADLLLRIQAEDTDRHWLIPERKGLVYTELERYGDGDRLLQMTVSPQARKKNPALPTHWQVRAVTYEVAGKEKTVFTSLPVARFSAAQVATLYHERWEIELGYRDIKSAMQHNAITLRSKKVDLVYQELWGLLLGYNLVRREASQAAVAHQRAPNEVSFKFACQFIANQMAVMAGALSPAHTPRRLAELRGCIGVMFIEKRPRPSRPRAVKISKTRFPVDRNAAPLK
>NZ_CP047962.1|WP_005325507.1|3102800_3103046_-|molybdopterin-synthase-sulfur-carrier-subunit
MIKVLFFAQVRELVGCDELSLPSDYPTAEQLRAALCERGDKWALALESGKLLVAVNQTLVPLETALNDGDEVAFFPPVTGG
>NZ_CP047962.1|WP_005325509.1|3103042_3103537_-|cyclic-pyranopterin-monophosphate-synthase-MoaC
MNLTHLNQSGEAHMVDVTDKQVTEREARAEAFVTMAPATLALILGGQHHKGDVFATARIAGIMAAKKTADLIPLCHPLALTRVEVEIDAQPEHNRVHIRTLCKLSGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIEQVRLVEKKGGKSGHFQLGSQAGEKA
>NZ_CP047962.1|WP_041207033.1|3103618_3104146_-|molybdenum-cofactor-biosynthesis-protein-B
MAPKHNEFIPLKIAVLTVSDSRTAADDSSGDYLVSALTEAGHQLTDRALCPDNLFRIRAQVSDWIVDDGVQVVLINGGTGFNEQNRVPEAVGVLFERTVQGFGEMFRQLSFAEIKGSAMQSRALAGLANRTLICCLPGSTGACQLGWEQLIRDQLDARTRPCNFVAHLSTSAIPA
>NZ_CP047962.1|WP_005325513.1|3104367_3104958_-|cytochrome-c3-family-protein
MKLPGFIQRLWTTFKSPSKAALWVLLLMGFFGGVIFWGGFNTAMEASNTEKFCTGCHEMKDNVFVEYRDTIHYANRSGVRASCPDCHVPHEWTYKIIRKVQASKELWGMITGKVDTREKFESHRREMAEREWQRMKDTDSRECRNCHNFEYMDFSLQGKRGAQMHSTSLASGESTCIDCHKGIAHQLPDMKGVEGF
>NZ_CP047962.1|WP_041206124.1|3104969_3105425_-|nitrate-reductase-cytochrome-c-type-subunit
MKKLIGAMLACLMAGSLMAATPEITNSTGGIKSERGSTDLVTDADAAPMKNYRKDGDLYDRQYMHQPPLIPHDTRNYEVDNKVNKCLACHSFKNASKMKAPKISPTHFETRDGMTLGEVSPRRYFCLQCHVPQADAKPLVENTFKPVEALN
>NZ_CP047962.1|WP_041206126.1|3105424_3106300_-|quinol-dehydrogenase-ferredoxin-subunit-NapH
MSRYPGAEASARLGWWRAHRFLLLRRLCQFGVLGLFLLGPLAGVWILKGNLSSSLLLETVPLTDPLTLLQSVAAGHWPITTLWLGAGLVLLGYWLVGGRVFCSWVCPVNLVTDAAAWLRARLGLKGNGQFNRNTRYWLLAMVLVAPAITGVLVWELVNPVSLAMRGLLFGMGAGWGLLVALFLFDLFVVERGWCGHLCPVGAFYALVNRVGFIKISAKGRERCSNCMDCYAVCPERPILRGPVHGARRGHGPLIVAQECTNCGRCIDVCAEQVFEITTGFAVKAEKTSENK
>NZ_CP047962.1|WP_005325518.1|3106296_3107031_-|ferredoxin-type-protein-NapG
MSRSRRQFLADLAKGACSVGLLGVGLGSVARQQVQAVPAQALRPPAALGEADFLGACVRCGLCVEACPYDTLKLARLLDPVTTGTPYFEARSVPCEMCDDIPCVVACPSGALDQGMTDIDQARMGVAVLIDHETCLNYLGLRCDVCYRVCPLIDKAITLELQRNPRTGKHAMFLPTVHSDICTGCGKCEHACVLETAAIKVVPRQLAKGELGHHYRLGWEEKAKAGKSLIGERLTLPTRKPEGL
>NZ_CP047962.1|WP_041206127.1|3107044_3109534_-|nitrate-reductase-catalytic-subunit-NapA
MKLSRRDFMKANAVAAAAAVAGVSAPTLAANLITSTDKTAITWDKAPCRFCGTGCSVLVGSQAGRVVATQGDPDAPVNRGLNCIKGYFLSKIMYGEDRLTQPMLRMTNGKFDKNGDFAPISWDQAFDIMAEKFKATLKEKGPTAVGMFGSGQWTVWEGYAAAKLMKAGLRTNNLDPNARHCMASAVVGFMRTFGMDEPMGCYDDIEQADAFVLWGSNMAEMHPILWSRMSDRRLSNPDVQVHVLSTFEHRSFELADNGMVFTPQTDLAILNYIANYIIQNDKVNWDFVNKHTQFRKGVTDIGYGLRPTHPTQQKAKNPDSGDSTPMSFDDFAKFVADYDVESVAKLSGVSKDKLEKLAQIYADPDKKVVSYWTMGFNQHTRGVWANNLCYNIHLLTGKISTPGSGPFSLTGQPSACGTTREVGTFAHRLPADMVVTDPKHRAIAEKIWKLPEGTIPEQVGYHAVLQNRMLKDGKLNAYWVMCNNNMQAGPNMNEEGLPGYRNPANFIVVSDPYPTVTAQAADLILPTAMWVEKEGAYGNAERRTQFWHQQVKAPEGAKSDLWQLMEFSKRFTVEEVWPAELIAKMPEVKGKTLFEVLYANGQVNQFPKEQSKGALNDEAEHFGFYVQKGLFEEYASFGRGHGHDLAPFDQYHEARGLRWPVVDGKETLWRYREGFDPYVKAGEGVKFYGKPDGKAVIFALPYEPAAEAPDKEYDMWLSTGRVLEHWHTGTMTRRVPELYRAFPDAVLFMHPEDAKARGVRRGEEVIVSSRRGEVKTRVETRGRNRPPKGLVFMPFFDAIQLVNKLTLDATDPLSKQTDYKKCAVKVMKA
>NZ_CP047962.1|WP_041204444.1|3109660_3109927_-|chaperone-NapD
MTREEFHVSSLVVLTQPPLRHRLAEQIAALDGAEIHAVSDEGKLVVTLEGPSQRPIMAAIDAINAMPGVLSAALIYHQFDEVEAEGRE
>NZ_CP047962.1|WP_041206129.1|3109959_3110469_-|ferredoxin-type-protein-NapF
MPDGVNLSRRSLFRGRLSAPRPEVQLPWSVSWADFVADCTRCGDCLTACPEQILIKGDGGFPTVDFQRGECTFCGECVSACQVPVFRPTTQTPWDYVAHIEAGCLASAQVFCQRCQDSCEQQAIRFSPQLGRVPTPSIHTESCNGCGACVADCPVGSIRVGAPHEGSAR

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Crispr_ID: NZ_CP047962_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047962_5

3190528-3190632

Orphan

Consensus_repeat	Method
CGATCAGAGCAGCGCGGCCACTTCGTCGGAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP047962_5

>merge|NZ_CP047962|5|3190528-3190632|CRISPRCasFinder
CGATCAGAGCAGCGCGGCCACTTCGTCGGAGGTGACACCGTTGTGGTGCACCTCCTATCGCTAGTTGCTGCTGACGATCAGAGCAGCGCGGCCACTTCGTCGGAG

>NZ_CP047962|5|5|3190528-3190632|CRISPRCasFinder
CGATCAGAGCAGCGCGGCCACTTCGTCGGAG	GTGACACCGTTGTGGTGCACCTCCTATCGCTAGTTGCTGCTGA
CGATCAGAGCAGCGCGGCCACTTCGTCGGAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047962.1\|WP_041206156.1\|3201801_3202095_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047962.1\|WP_005325697.1\|3194868_3195609_+\|carboxy-S-adenosyl-L-methionine-synthase-CmoA	unknown	unknown	gnl\|CDD\|273244
NZ_CP047962.1\|WP_005325679.1\|3178876_3180538_-\|glutamine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235424
NZ_CP047962.1\|WP_005325703.1\|3197427_3198966_+\|inactive-transglutaminase-family-protein	unknown	unknown	gnl\|CDD\|379600
NZ_CP047962.1\|WP_005325699.1\|3195605_3196583_+\|tRNA-5-methoxyuridine(34)/uridine-5-oxyacetic-acid(34)-synthase-CmoB	unknown	unknown	gnl\|CDD\|237898
NZ_CP047962.1\|WP_005325707.1\|3200239_3201154_+\|hydrogen-peroxide-inducible-genes-activator	unknown	unknown	gnl\|CDD\|176103
NZ_CP047962.1\|WP_005325675.1\|3177585_3178086_-\|DUF4442-domain-containing-protein	unknown	unknown	gnl\|CDD\|373120
NZ_CP047962.1\|WP_041206155.1\|3201271_3201718_+\|peptidase-P60	unknown	unknown	gnl\|CDD\|236773
NZ_CP047962.1\|WP_005325692.1\|3191413_3193192_-\|aspartate--tRNA-ligase	unknown	unknown	gnl\|CDD\|234775
NZ_CP047962.1\|WP_005325688.1\|3188632_3190258_-\|phosphoethanolamine--lipid-A-transferase	unknown	unknown	gnl\|CDD\|183224
NZ_CP047962.1\|WP_005325683.1\|3183663_3185118_-\|PTS-transporter-subunit-EIIC	unknown	unknown	gnl\|CDD\|273920
NZ_CP047962.1\|WP_005325701.1\|3196635_3197424_+\|ATP-dependent-zinc-protease	unknown	unknown	gnl\|CDD\|226553
NZ_CP047962.1\|WP_005325705.1\|3198969_3199935_+\|alpha-L-glutamate-ligase-like-protein	unknown	unknown	gnl\|CDD\|274070
NZ_CP047962.1\|WP_005325685.1\|3185389_3186190_+\|glucosamine-6-phosphate-deaminase	unknown	unknown	gnl\|CDD\|179028
NZ_CP047962.1\|WP_041206154.1\|3187349_3188564_+\|ROK-family-protein	unknown	unknown	gnl\|CDD\|366120
NZ_CP047962.1\|WP_005325673.1\|3177014_3177539_+\|flavodoxin-FldA	unknown	unknown	gnl\|CDD\|236439
NZ_CP047962.1\|WP_005325677.1\|3178330_3178759_+\|ferric-iron-uptake-transcriptional-regulator	unknown	unknown	gnl\|CDD\|236527
NZ_CP047962.1\|WP_161507385.1\|3180877_3183541_-\|family-20-glycosylhydrolase	unknown	unknown	gnl\|CDD\|119337
NZ_CP047962.1\|WP_005325686.1\|3186199_3187345_+\|N-acetylglucosamine-6-phosphate-deacetylase	unknown	unknown	gnl\|CDD\|183010
NZ_CP047962.1\|WP_005325694.1\|3193624_3194485_+\|DUF72-domain-containing-protein	unknown	unknown	gnl\|CDD\|182366

Protein	Function_ID	Function_description	E-value
NZ_CP047962.1\|WP_005325697.1\|3194868_3195609_+\|carboxy-S-adenosyl-L-methionine-synthase-CmoA	gnl\|CDD\|273244	TIGR00740, tRNA_cmo5U34-methyltransferase, tRNA (cmo5U34)-methyltransferase. This tRNA methyltransferase is involved, together with cmoB, in preparing the uridine-5-oxyacetic acid (cmo5U) at position 34. [Unknown function, Enzymes of unknown specificity].	9.911e-133
NZ_CP047962.1\|WP_005325679.1\|3178876_3180538_-\|glutamine--tRNA-ligase	gnl\|CDD\|235424	PRK05347, PRK05347, glutaminyl-tRNA synthetase; Provisional.	0
NZ_CP047962.1\|WP_005325703.1\|3197427_3198966_+\|inactive-transglutaminase-family-protein	gnl\|CDD\|379600	pfam14402, 7TM_transglut, 7 transmembrane helices usually fused to an inactive transglutaminase. A family of seven transmembrane helices fused to an inactive transglutaminase domain. The transglutaminase domain is predicted to be extracellularly located. Members of this family are associated in gene neighborhoods with a pepsin-like peptidase and an ATP-grasp of the RimK-family. The ATP-grasp is predicted to modify the 7TM protein or a cofactor that interacts with it.	7.905e-151
NZ_CP047962.1\|WP_005325699.1\|3195605_3196583_+\|tRNA-5-methoxyuridine(34)/uridine-5-oxyacetic-acid(34)-synthase-CmoB	gnl\|CDD\|237898	PRK15068, PRK15068, tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic acid(34) synthase CmoB.	0
NZ_CP047962.1\|WP_005325707.1\|3200239_3201154_+\|hydrogen-peroxide-inducible-genes-activator	gnl\|CDD\|176103	cd08411, PBP2_OxyR, The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily. OxyR senses hydrogen peroxide and is activated through the formation of an intramolecular disulfide bond. The OxyR activation induces the transcription of genes necessary for the bacterial defense against oxidative stress. The OxyR of LysR-type transcriptional regulator family is composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The C-terminal domain also contains the redox-active cysteines that mediate the redox-dependent conformational switch. Thus, the interaction between the OxyR-tetramer and DNA is notably different between the oxidized and reduced forms. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	4.31363e-79
NZ_CP047962.1\|WP_005325675.1\|3177585_3178086_-\|DUF4442-domain-containing-protein	gnl\|CDD\|373120	pfam14539, DUF4442, Domain of unknown function (DUF4442). This family of proteins is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 139 and 165 amino acids in length. There is a conserved PYF sequence motif. There is a single completely conserved residue N that may be functionally important.	1.86327e-28
NZ_CP047962.1\|WP_041206155.1\|3201271_3201718_+\|peptidase-P60	gnl\|CDD\|236773	PRK10838, spr, bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase.	3.27701e-42
NZ_CP047962.1\|WP_005325692.1\|3191413_3193192_-\|aspartate--tRNA-ligase	gnl\|CDD\|234775	PRK00476, aspS, aspartyl-tRNA synthetase; Validated.	0
NZ_CP047962.1\|WP_005325688.1\|3188632_3190258_-\|phosphoethanolamine--lipid-A-transferase	gnl\|CDD\|183224	PRK11598, PRK11598, putative metal dependent hydrolase; Provisional.	0
NZ_CP047962.1\|WP_005325683.1\|3183663_3185118_-\|PTS-transporter-subunit-EIIC	gnl\|CDD\|273920	TIGR01998, N-acetylglucosamine_and_glucose_PTS, PTS system, N-acetylglucosamine-specific IIBC component. This model represents the combined B and C domains of the PTS transport system enzyme II specific for N-acetylglucosamine transport. Many of the genes in this family also include an A domain as part of the same polypeptide and thus should be given the name "PTS system, N-acetylglucosamine-specific IIABC component". This family is most closely related to the glucose-specific PTS enzymes. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	0
NZ_CP047962.1\|WP_005325701.1\|3196635_3197424_+\|ATP-dependent-zinc-protease	gnl\|CDD\|226553	COG4067, COG4067, Uncharacterized protein conserved in archaea [Posttranslational modification, protein turnover, chaperones].	1.3248e-49
NZ_CP047962.1\|WP_005325705.1\|3198969_3199935_+\|alpha-L-glutamate-ligase-like-protein	gnl\|CDD\|274070	TIGR02291, conserved_protein_of_unknown_function, alpha-L-glutamate ligase-related protein. Members of this protein family contain a region of homology to the RimK family of alpha-L-glutamate ligases (TIGR00768), various members of which modify the Glu-Glu C-terminus of ribosomal protein S6, or tetrahydromethanopterin, or a form of coenzyme F420 derivative. Members of this family are found so far in various Vibrio and Pseudomonas species and some other gamma and beta Proteobacteria. The function is unknown.	2.73076e-160
NZ_CP047962.1\|WP_005325685.1\|3185389_3186190_+\|glucosamine-6-phosphate-deaminase	gnl\|CDD\|179028	PRK00443, nagB, glucosamine-6-phosphate deaminase; Provisional.	1.38008e-175
NZ_CP047962.1\|WP_041206154.1\|3187349_3188564_+\|ROK-family-protein	gnl\|CDD\|366120	pfam00480, ROK, ROK family.	1.2933e-71
NZ_CP047962.1\|WP_005325673.1\|3177014_3177539_+\|flavodoxin-FldA	gnl\|CDD\|236439	PRK09267, PRK09267, flavodoxin FldA; Validated.	2.1061e-106
NZ_CP047962.1\|WP_005325677.1\|3178330_3178759_+\|ferric-iron-uptake-transcriptional-regulator	gnl\|CDD\|236527	PRK09462, fur, ferric uptake regulator; Provisional.	1.22597e-102
NZ_CP047962.1\|WP_161507385.1\|3180877_3183541_-\|family-20-glycosylhydrolase	gnl\|CDD\|119337	cd06569, GH20_Sm-chitobiase-like, The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin. Chitin is degraded by a two step process: i) a chitinase hydrolyzes the chitin to oligosaccharides and disaccharides such as di-N-acetyl-D-glucosamine and chitobiose, ii) chitobiase then further degrades these oligomers into monomers. The GH20 hexosaminidases are thought to act via a catalytic mechanism in which the catalytic nucleophile is not provided by solvent or the enzyme, but by the substrate itself.	0
NZ_CP047962.1\|WP_005325686.1\|3186199_3187345_+\|N-acetylglucosamine-6-phosphate-deacetylase	gnl\|CDD\|183010	PRK11170, nagA, N-acetylglucosamine-6-phosphate deacetylase; Provisional.	0
NZ_CP047962.1\|WP_005325694.1\|3193624_3194485_+\|DUF72-domain-containing-protein	gnl\|CDD\|182366	PRK10302, PRK10302, hypothetical protein; Provisional.	3.15167e-102

>NZ_CP047962.1|WP_005325688.1|3188632_3190258_-|phosphoethanolamine--lipid-A-transferase
MRLTLGVMKVNLLLVLLFALVFNWPIFLHFYRILTALEHVKAGFALSIPLVLIAALNAVFLPFTFRYLLKPFFILLIMTASLVSYAMLKYGIIFDVGMVQNILETNSGEATSYLNASVVLWFLLTAVLPVLGLLWIKVEYPTPWYKGLGLRLGSIALSLLFLVGVAALYYQDYASVGRNNHSIVKEIVPSNYVRGLYRYARDILFATPVPYEPIGTDARVVAKSDKPTLMFLVVGETARSQNYSLNGYQKQTNGFTMKEPDLVSFRDVRSCGTATAVSVPCMFSNLTRREYDETLAKSRDGLLDVLQHAGVSVLWKENDGGCKGVCNHVPTLEIEPKTFPEYCEGDSCYDEVLLQGLDQQIAGMKGKQGSKLVAFHLMGSHGPTYYRRYPAADRVFLPDCPRSDIENCSNEELVNTYDNTIRYTDKVLSQLIDKLKTLESQYNVGLVYLSDHGESLGAMGLYLHGTPYKFAPDDQTRVPLLTWFSPQLQRDRQLDQDCLRQEAGSKRFSHDNLFHSMLGIMDVQTQAYDGKLDLFKPCRAG
>NZ_CP047962.1|WP_041206154.1|3187349_3188564_+|ROK-family-protein
MTGGQIANVDLIKQVNSAVVYRLIDLQGPISRVKIAELSQLAPASVTKITRQLIEHGLIRETSPQASTGGRRAISLTTIKHRFQFVSAKLGRGYLQLSLYDLDGKELDQHITQVTEIEQQPVVDMLLREIGAFIDANTERSRNLISIALTMPGLVNPESGMVIYTPTYQIRNLGLAKLLEHHFNLPCYVGNDTRSLALAEHFFGESRDCMDSILVSVHQGTGSGIITKGQVFLGHNRNVGEIGHIQVEPLGKRCHCGNFGCLETIASNEAIVDKVKELISRGHLSSLQEKHITIQEVCKAAMAGDELARSVIENVGEHLGRAIAITVNLFNPQKVLIAGEITAAEEILIPAIRRCVEHQSLPSFHRGLPIVKARFQNQPTIGGFALVKRSLLEGDLLQIIMEQK
>NZ_CP047962.1|WP_005325686.1|3186199_3187345_+|N-acetylglucosamine-6-phosphate-deacetylase
MYALTNCTLYTGSCVLTGHGVLIEGDKIVAISHLAELPAGIERIDLKGANLSAGFIDVQLNGCGGVMFNGHITTQTLATMQAANLKSGTTSFLPTLITSPDADMKLAVAVTRDYMAAHPNEVLGVHLEGPYTNLKRKGIHPAEQIRQPVDEMIDFFCANSDAIAKITLAPERNKPEHIRRLVEAGILVSAGHTAASYDQAMAGFDNGMRFATHLYNAMTPTLNGREPGVVGAIYDRKDVYAGVIVDGHHVHWANVRLAHRILGEKLVLVTDATAAAGAPEGFEQFDFCGATVYFRDGQCVDENGTLGGSALTMIEGVENLVKQVGLPLDEALRMATLYPARAIGWDSRLGSIQVGKIANLTVFDQAFTVCGTVVNGHYTTQ
>NZ_CP047962.1|WP_005325685.1|3185389_3186190_+|glucosamine-6-phosphate-deaminase
MRLIPLKSASQVGLWSARYIVDRINAFKPTSDRPFVLGLPTGGTPLTTYKRLIELHQAGEVSFQNVVTFNMDEYVGLPKEHPESYHSFMHNNFFNQVDIRPENINILNGNAEDLVAECKRYEDKIKSYGKINLFMGGVGNDGHIAFNEPASSLASRTRVKTLTEDTRIANSRFFGGDMEQVPKLALTVGVGTLMDAEEIMILVTGHAKALALQAAVEGCVNHMWTISTLQLHPKGMMVCDEPSTMELKVKTVRYFQQLEAANIDRL
>NZ_CP047962.1|WP_005325683.1|3183663_3185118_-|PTS-transporter-subunit-EIIC
MNILGYLQKIGRALMVPVAVLPAAAILMGIGYWIDPNGWGGESALAAFLIKAGAAIIDKMAILFAVGVAYGMSKDKDGSAALAGLVGYLVVTTLLSPGAVSQIQQIPLDQVPAAFGKIENQFIGILTGVIAAELYNRFSGVELHKALAFFSGRRLVPIVTSVVMIVVSFILMAVWPIIYGGLVSFGESIVSMGSTGAGIYAFFNRLLIPVGLHHALNSVFWFDVAGINDIPNFLGGQSSIDAGKAVVGVTGMYQAGFFPIMMFGLPGAALAIYHSAKKENKEKVASIMIAAAFAAFFTGVTEPLEFSFMFVAPVLYVIHALLTGLSVFIAASMHWISGFGFSAGFVDMFIQSRNPLATQWYMLLVQGLVFFGLYYAIFRAVIVKFNLKTPGREDDEAVPVQAQTTDRTELARQYLEVLGGQDNLVTIDACITRLRLTLKDRSIVDERKLKALGAAGVVKLGEQNLQVILGPLAEIIAGEMKALR
>NZ_CP047962.1|WP_161507385.1|3180877_3183541_-|family-20-glycosylhydrolase
MNLKHSLLAIAMSTVFVSQVQAADAAKQAVVDSLASNLVVKYEVVTNDGAGAGLDCQALGSEWASCGVAKLHLTNTGADVTSKDWSIYVSSIRRIQRVDNDQFTITHLTGDLYRLTPTEKFQGFAKDATVEVPLVVEYWVLFESDIMPNWYVASEGAEPKVLASMSNIDDATTYEKPMPADGWKRTKDDNNILMNSETRFAANQTSTLLPAGKIDDQILPSPMKQVVKAGPQVDFSTIKLNALDLPSDRAEALKAQLTKLGVTLSDTGYPVTIKLGSKLKQAEGYDMTIGAKGTVVQGHDIDGAFWGAQSLISLLGVDDKLVSQMSIEDAPRFEYRGMQTDVARQFRSPETMKKLVDQMSAMKLNVLHLGLTNDEGWRIEIPGLPELTDVGSQRCHDESETKCLMPQLGSGPTSDNQGSGFYSKADYIDLVRYAKARGVTVIPEINMPAHARAAVVSMEAHYKRLLAEGKEAEANQFRLTDPDDTSNVTSVQFYDKMSFINPCQPGAATFVAKVMDEVAQMHQAAGQPLTAWHYGGDEAKNIMQGGGYQDPAVTKKEELVAWKGNVDSSKQDKPFGKSPLCQKMIDDGKLKDVAELPVHFAKEVSEMVKGHGFSTLQAWEDGLKYATDASVFATDKTRVNFWETLYWGGFNEAMKWAHKGYDVVLSNPDYLYFDFPNEVHPAERGYYWATRFNDTRKVFAFAPENLPQNAETSVDRDGNAFVAKGDQDPVKFKGISGQQWSETVRTDAQYEYMVYPRIFSVAERAWHKGGFELDYVKGREFSGTTKHVNKATLNKEWNQFANLLGQRVLPKLDQAGVEYRLSVPGAKVVNGKLEANVDLPGLPIQYSLDGTNWTAYDAAAKPSVTGKVWLRTTSFDGKRTSRVTELN
>NZ_CP047962.1|WP_005325679.1|3178876_3180538_-|glutamine--tRNA-ligase
MSEASSPTNFIRQIIDEDLASGKHKSVHTRFPPEPNGYLHIGHAKSICLNFGIARDYQGQCNLRFDDTNPAKEDIEFVESIKQDVQWLGFQWSGEICYSSDYFDKLHGYAIELIEKGLAYVDELSPEQMREYRGTLTAPGKNSPFRDRSVEENLALFAKMKSGEMAEGSACLRAKIDMASPFMVMRDPVIYRIKFAHHHQTGDKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRLYDWVLDNISIDCHPRQYEFSRLNLEYTVMSKRKLNLLVTEGHVSGWDDPRMLTVSGLRRRGYTPASIREFCQRIGVTKQDNIVEMSMLEACIRDDLNENAPRAMAVLHPVKVVIENLAADEVLTAPAHPSNAEMGTRELNFTREIFIDEADFKEEANKQFKRLVLGKEVRLRNAYVIKAERVEKDADGKVTCIYCSYDPETLGKDPADGRKVKGVIHWVSATHSLPAEIRLYDRLFKMPNPGAEDDFEAALNPDSLVIIAGARVEASLKDAKPEFAYQFEREGYFCADNKLSSPEHLVFNRTVALRDVWGKAEA
>NZ_CP047962.1|WP_005325677.1|3178330_3178759_+|ferric-iron-uptake-transcriptional-regulator
MADNNQALKKAGLKITLPRVKILEILQQPDCQHTSAEDLYKRLIDQGEEIGLATVYRVLNQFDDAGIVTRHHFEGGKSVFELATQEHHDHLVCLDCGKVIEFSDEVIEQRQRDIAKHHNIRLTNHSLYLYGHCVNGDCKHDE
>NZ_CP047962.1|WP_005325675.1|3177585_3178086_-|DUF4442-domain-containing-protein
MDWLFDNAAWVRHALNAWPPFWGAGIKIETLSPDFRFCRVTLKSRWWNKNANRTQFGGSMFAMTDPIYPLMLMGHFKNRYYVWDKAGSINFIKPGKGMLVAEFNLTDAKLASIVAATEGGNKHFPEFEVQVQDKRGELVAQVRRTLYVKPKPEHRTPGQAASTMKE
>NZ_CP047962.1|WP_005325673.1|3177014_3177539_+|flavodoxin-FldA
MASVGLFFGSDTGNTEAVAKMIQKELGKQLIEVRDIAKSSKADIDSFDLLMFGIPTWYYGEAQADWDDFFPELEEIDFNNKLVAIFGCGDQEDYSEYFLDAMGTLRDIVEAKGAIIIGHWPTASYEFEASKALVDDKHFVGLGIDEDRQPELTAERVKGWCKQLHEEMCLSELE
>NZ_CP047962.1|WP_005325692.1|3191413_3193192_-|aspartate--tRNA-ligase
MRSIYCGQVNEAHAGQTITLCGWVHRRRDLGGLIFIDMRDREGIVQVFFDPDKPDAFALASELRGEFCIQVTGVVRTRPDSQRNSDMATGAIEVFAHELTIINRAEPLPLDFNQVNSEEISLKYRYLDLRRPEMAKYLKTRAKASAFVRRFMDEQGFLDIETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDVETSFMTAPQVREIMEEMIRKLWLHILNVDLGDFPIMTFDEAMRRFGSDKPDLRLPMELVDVADLLTAVEFAVFAGPANDPKGRVAALKVPGGAELSRKQIDEYTKFVGIYGAKGLAWMKVNEAANGIEGVQSPVAKFLTDEIVREILARTGAADGDILFFGADSKKVVCDAMGALRLKVGRDLGLVENVWKPLWVIDFPMFEEDGEGGLAAMHHPFTAPSNLGPSELKANPLGAYANAYDMVINGYEVGGGSVRIHNSEMQSTVFDILGITPDEQRLKFGFLLDALKYGTPPHAGLAFGLDRLSMLLTGTDNIRDVIAFPKTTAAACLMTDAPSFANQAQLTELAIATVAKADAKADA
>NZ_CP047962.1|WP_005325694.1|3193624_3194485_+|DUF72-domain-containing-protein
MSLYLGLPQWSHPAWPGQLLGVGARPAEHLAHYARVFNTVEGNTTFYASPTPDTVRRWADAVPPQFRFSFKFPKEISHQSDLVSAGKQVADFITLLGPLHGQLGLLKLQLPARFGPAGLPRLAAFFEGLPPDFTYALEVRHPDFFAKGEAERALNRLLMDKGINRIMLDSRPLFSVPASLAAKNAALVDAQGKKPRLPVHLLATANSPVVRLIGLPHPEDNHPFLPSWLPRWQQWLAEGKNLYLFIHTADNARAPELARQVSRLLGQEMAPWPGENDRARQGLLPF
>NZ_CP047962.1|WP_005325697.1|3194868_3195609_+|carboxy-S-adenosyl-L-methionine-synthase-CmoA
MHDQIFAAPIAQLGDFCFDEQVVDVFPDMIQRSVPGYSNIISAIGMMAARYAQPQSRLYDLGCSLGAATQAMRRHVNQPGCQITAVDLSHPMIERARAHLSGFKSEVPVELVEADICDIAIENASVVVLNFTLQFVAPEKRAALIQRIHDGLRPGGILILSEKFRFEDEQVNALLIDLHLDFKRANGYSELEISQKRTALENVMRTDSLEIHRARLRDAGFTHQDLWFQCFNFGSMIAIKSSDAQP
>NZ_CP047962.1|WP_005325699.1|3195605_3196583_+|tRNA-5-methoxyuridine(34)/uridine-5-oxyacetic-acid(34)-synthase-CmoB
MIDFANFYQLIAKNRLSHWLHTLPAQLHAWQHDNLHGDLPRWNRALNKLPQVAPGNVELKSRVEVGGMDSLNEGERKKTESLLRQFMPWRKGPFTVHGIHIDTEWRSDWKWERVLPHISPLAGRYVLDVGCGSGYHLWRMVGEGAKLAVGIDPSPLFLCQFEAIRHFAGNDQRAHLLPLGIQELPELRAFDTVFSMGVLYHRKSPIEHIEQLRNQLKDDGELVLETLVIDGGVNDVLVPTDRYGKMRNVWFIPSSAALKLWVERCGFSDVRIVDENMTSTDEQRRTDWMINESLSDYLDPDDPALTVEGYPAPKRAVLIARKAKD
>NZ_CP047962.1|WP_005325701.1|3196635_3197424_+|ATP-dependent-zinc-protease
MNDMKSKLKGMTLLSLLSLGGCVSMEKAPPAPTLTLAELRNEITLSEQRLQTSMEQQQKQYVQQQHLLVQLNTDVTNMKESVKKVDSKLATLPPEPPKPMAIPTEKCPAPSQGHTVDGKLLVGEAEWIWVDAANDAFQARVDTGATTSSISAQEITIFERNGKNWVRFFLSHQEMDDKIQIEAPLVRHVRVRQASADDLDRRPVVRLTVRIGDMTEKAEFTLKDRSDMTFPVLLGREFLKDIAVVDVAREYIQPKPKLKDVK
>NZ_CP047962.1|WP_005325703.1|3197427_3198966_+|inactive-transglutaminase-family-protein
MVSRKPFYLLVALLFIVGLGMTFYHHVALDVPLTPGEKRQIWSIEAKLEFEATGEPVIASLAIPGTQPGFTLMNENAASPGYGLSFVEKDGDARAEWSIRTASGRQELYYRVDMMADAHAKPAANPLPPAIEKQIESEPYATAMKQILERAQERSADGYTLTREIIKEIEKQEQNAELLKSHKSRASLIAELLNNAEVPARVVHALSLEDGRRRQELVDYLQVFNSPTDYKLFNPQTGEQGQPGNLLLWEYNSGALLDVTGGHNSRVTFSMIEQEQPVNVALAQKFEKSEMMNFSIHSLPLEEQALFKGLLLIPIGVLMVVFLRVLVGIKTSGTFMPVLIAVAFIQTSLVTGLIGFLLIVGTGLVIRSYLSRLNLLLVARISAIIIMVISMIGIFSAFAFKLGLTDGMKITFFPMIILSWTIERMSILWEEEGPKEVFRQGGGSLLVAVIAYLAMDNELIRHLTFNFLGLQLVLMATVLVMGNYTGYKLSELKRFKPLVDEMKSGATPGKDK
>NZ_CP047962.1|WP_005325705.1|3198969_3199935_+|alpha-L-glutamate-ligase-like-protein
MWFWQKYTSPWSLSQAGILGMNKRNHSYISRYNPRRLYPLVDDKLKTKRIALDAGVTVPELIGTIREQHDVTRITELVKDWPGFCIKPARGSGGKGILVILRQEEGSFYKPNGSASTGQDLERHVSNILAGLYSLGGKPDVALVEGLINFDDVFDGYSFEGVPDARVIIFKGFPVMAMMRLSTAASDGKANLHQGAVGVGLCLRTGRALRAVQFGNPLRHHPDTGLDLYDLKVPHWDTLLTLAASCYEMSGLGYIGTDMVLDKFRGPMLLELNARPGLAIQIANGRGLVPNLKTIEKLGQVKMNVEQRVNFAKDHFGIFDE
>NZ_CP047962.1|WP_005325707.1|3200239_3201154_+|hydrogen-peroxide-inducible-genes-activator
MQRWPSLKQLQYLVALDEHKNFNRAAKACHVSQSTLSTGIQTLEDMMNLQLVERDHKSFIMTPVGMEIVARARNLLSDARDLMELSQQQGGVMHGTVRLGCIPTIAPFLLSKLLQVCGKAYPELELLLREDTTTNLLKQLEQGQLDLLILALPVEIGGFHCKTVGQDPFHMVMPSHMAAGLHMPFDYKELPNQSIFLLEREHCLTEHAVSACRLRDKSKINPFAATSLHTLVQMVGAGLGTTFLPQMAIDAGILENSDLVAIPLPGEKPYREIGLVWRPSTTRVQTFYKIAELLTPLITPKAAD
>NZ_CP047962.1|WP_041206155.1|3201271_3201718_+|peptidase-P60
MFRTLLPPLLALFVIACSSTPEPPPARQASAFDGFYQQWRGVPYRMGGTNRAGLDCSAFTQLAYQQVLGFTLPRTTESQASLGRPVDRYRLQHGDLVFFKTGWQQYHVGVYTGSGEFIHASTSKGVIRSRLDNVYWNSRYWQARRLTQ
>NZ_CP047962.1|WP_041206156.1|3201801_3202095_-|hypothetical-protein
MTRELHSLLARLDDVIERMPDSFNTYEFAQKLALQHQREYFAAGHSLAEQDKNLLRLLHEKIALALASHDGVIEGALLPCVTPWGERATSPRWHRKH

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Crispr_ID: NZ_CP047962_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047962_6

3595842-3595917

Orphan

Consensus_repeat	Method
GCACTTATTATCTGAATTCCCGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP047962_6

>merge|NZ_CP047962|6|3595842-3595917|CRISPRCasFinder
GCACTTATTATCTGAATTCCCGGACCGCCTCTCTCCTATGCACCATGGGCATTGCACTTATTATCTGAATTCACGG

>NZ_CP047962|6|6|3595842-3595917|CRISPRCasFinder
GCACTTATTATCTGAATTCCCGG	ACCGCCTCTCTCCTATGCACCATGGGCATT
GCACTTATTATCTGAATTCACGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047962.1\|WP_005328684.1\|3597942_3599043_-\|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC	unknown	unknown	gnl\|CDD\|236947
NZ_CP047962.1\|WP_005332494.1\|3589619_3590240_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379995
NZ_CP047962.1\|WP_161507488.1\|3586919_3587519_-\|HAD-family-phosphatase	unknown	unknown	gnl\|CDD\|319790
NZ_CP047962.1\|WP_019706001.1\|3594810_3595758_-\|IS30-like-element-ISAs2-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_CP047962.1\|WP_081934583.1\|3605305_3606946_-\|SulP-family-inorganic-anion-transporter	unknown	unknown	gnl\|CDD\|223732
NZ_CP047962.1\|WP_161507493.1\|3604162_3605032_+\|polyphosphate-kinase-2	unknown	unknown	gnl\|CDD\|213852
NZ_CP047962.1\|WP_041206300.1\|3599115_3599943_-\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472
NZ_CP047962.1\|WP_012564931.1\|3593776_3594724_-\|IS30-like-element-ISAeca1-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_CP047962.1\|WP_025328009.1\|3587844_3589017_+\|prephenate-dehydratase	unknown	unknown	gnl\|CDD\|182594
NZ_CP047962.1\|WP_161507865.1\|3603842_3604166_+\|substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|380511
NZ_CP047962.1\|WP_042650348.1\|3589173_3589599_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225563
NZ_CP047962.1\|WP_005328673.1\|3600901_3602185_-\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|270451
NZ_CP047962.1\|WP_161507492.1\|3603630_3603798_+\|LacI-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525
NZ_CP047962.1\|WP_050504416.1\|3599944_3600835_-\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224096
NZ_CP047962.1\|WP_161507491.1\|3602251_3603328_-\|cellulase-family-glycosylhydrolase	unknown	unknown	gnl\|CDD\|226444
NZ_CP047962.1\|WP_005323562.1\|3592766_3593684_-\|IS5-family-transposase	unknown	unknown	gnl\|CDD\|290455
NZ_CP047962.1\|WP_161507490.1\|3596863_3597826_-\|family-43-glycosylhydrolase	unknown	unknown	gnl\|CDD\|350141
NZ_CP047962.1\|WP_161507487.1\|3585940_3586771_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224522
NZ_CP047962.1\|WP_161507489.1\|3590524_3591679_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379855
NZ_CP047962.1\|WP_161507863.1\|3591932_3592682_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236481

Protein	Function_ID	Function_description	E-value
NZ_CP047962.1\|WP_005328684.1\|3597942_3599043_-\|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC	gnl\|CDD\|236947	PRK11650, ugpC, sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC.	4.38217e-172
NZ_CP047962.1\|WP_005332494.1\|3589619_3590240_-\|hypothetical-protein	gnl\|CDD\|379995	pfam17680, FlgO, FlgO protein. This entry represents the FlgO protein. Mutation of this protein in Vibrio cholerae has been shown to reduce motility. FlgO is an outer membrane protein that localizes throughout the membrane and not at the flagellar pole. Although FlgO and FlgP do not specifically localize to the flagellum, they are required for flagellar stability. Proteins in this family mostly contain an N-terminal lipoprotein attachment motif.	1.81436e-46
NZ_CP047962.1\|WP_161507488.1\|3586919_3587519_-\|HAD-family-phosphatase	gnl\|CDD\|319790	cd02603, HAD_sEH-N_like, N-terminal lipase phosphatase domain of human soluble epoxide hydrolase, Escherichia coli YihX/HAD4 alpha-D-glucose 1-phosphate phosphatase, and related domains, may be inactive. This family includes the N-terminal phosphatase domain of human soluble epoxide hydrolase (sEH). sEH is a bifunctional enzyme with two distinct enzyme activities, the C-terminal domain has epoxide hydrolysis activity and the N-terminal domain (Ntermphos), which belongs to this family, has lipid phosphatase activity. The latter prefers mono-phosphate esters, and lysophosphatidic acids (LPAs) are the best natural substrates found to date. In addition this family includes Gallus gallus sEH and Xenopus sEH which appears to lack phosphatase activity, and Escherichia coli YihX/HAD4 which selectively hydrolyzes alpha-Glucose-1-P, phosphatase, has significant phosphatase activity against pyridoxal phosphate, and has low beta phosphoglucomutase activity. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	5.07523e-47
NZ_CP047962.1\|WP_019706001.1\|3594810_3595758_-\|IS30-like-element-ISAs2-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	1.20844e-94
NZ_CP047962.1\|WP_081934583.1\|3605305_3606946_-\|SulP-family-inorganic-anion-transporter	gnl\|CDD\|223732	COG0659, SUL1, Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism].	1.66454e-110
NZ_CP047962.1\|WP_161507493.1\|3604162_3605032_+\|polyphosphate-kinase-2	gnl\|CDD\|213852	TIGR03707, PPK2_P_aer, polyphosphate kinase 2, PA0141 family. Members of this protein family are designated polyphosphate kinase 2 (PPK2) after the characterized protein in Pseudomonas aeruginosa. This family comprises one of three well-separated clades in the larger family described by pfam03976. PA0141 from this family has been shown capable of operating in reverse, with GDP preferred (over ADP) as a substrate, producing GTP (or ATP) by transfer of a phosphate residue from polyphosphate. Most species with a member of this family also encode a polyphosphate kinase 1 (PPK1). [Central intermediary metabolism, Phosphorus compounds].	5.23174e-138
NZ_CP047962.1\|WP_041206300.1\|3599115_3599943_-\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	5.25405e-69
NZ_CP047962.1\|WP_012564931.1\|3593776_3594724_-\|IS30-like-element-ISAeca1-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	2.83568e-94
NZ_CP047962.1\|WP_025328009.1\|3587844_3589017_+\|prephenate-dehydratase	gnl\|CDD\|182594	PRK10622, pheA, bifunctional chorismate mutase/prephenate dehydratase; Provisional.	0
NZ_CP047962.1\|WP_161507865.1\|3603842_3604166_+\|substrate-binding-domain-containing-protein	gnl\|CDD\|380511	cd06288, PBP1_sucrose_transcription_regulator, ligand-binding domain of DNA-binding regulatory proteins specific to sucrose that are members of the LacI-GalR family of bacterial transcription repressors. This group includes the ligand-binding domain of DNA-binding regulatory proteins specific to sucrose that are members of the LacI-GalR family of bacterial transcription repressors. The LacI-GalR family repressors are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the sugar-binding domain of ABC-type transport systems that contain the type 1 periplasmic binding protein-like fold. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding affinity of the repressor.	1.23542e-20
NZ_CP047962.1\|WP_042650348.1\|3589173_3589599_-\|hypothetical-protein	gnl\|CDD\|225563	COG3018, COG3018, Uncharacterized protein conserved in bacteria [Function unknown].	1.87786e-13
NZ_CP047962.1\|WP_005328673.1\|3600901_3602185_-\|extracellular-solute-binding-protein	gnl\|CDD\|270451	cd14748, PBP2_UgpB, The periplasmic-binding component of ABC transport system specific for sn-glycerol-3-phosphate; possesses type 2 periplasmic binding fold. This group includes the periplasmic component of an ABC transport system specific for sn-glycerol-3-phosphate (G3P) and closely related proteins from archaea and bacteria. Under phophate starvation conditions, Escherichia coli can utilize G3P as phosphate source when exclusively imported by an ATP-binding cassette (ABC) transporter composed of the periplasmic binding protein, UgpB, the transmembrane subunits, UgpA and UgpE, and a homodimer of the nucleotide binding subunit, UgpC. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.05954e-61
NZ_CP047962.1\|WP_161507492.1\|3603630_3603798_+\|LacI-family-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	3.50479e-06
NZ_CP047962.1\|WP_050504416.1\|3599944_3600835_-\|sugar-ABC-transporter-permease	gnl\|CDD\|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	5.64306e-78
NZ_CP047962.1\|WP_161507491.1\|3602251_3603328_-\|cellulase-family-glycosylhydrolase	gnl\|CDD\|226444	COG3934, COG3934, Endo-beta-mannanase [Carbohydrate transport and metabolism].	0.000185897
NZ_CP047962.1\|WP_005323562.1\|3592766_3593684_-\|IS5-family-transposase	gnl\|CDD\|290455	pfam13737, DDE_Tnp_1_5, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.	3.05427e-53
NZ_CP047962.1\|WP_161507490.1\|3596863_3597826_-\|family-43-glycosylhydrolase	gnl\|CDD\|350141	cd18820, GH43_LbAraf43-like, Glycosyl hydrolase family 43 proteins similar to Lactobacillus brevis alpha-L-arabinofuranosidase LbAraf43 and Geobacillus thermoleovorans GbtXyl43B. This uncharacterized glycosyl hydrolase family 43 (GH43) subgroup belongs to a subgroup which includes enzymes with beta-xylosidase (EC 3.2.1.37), alpha-L-arabinofuranosidase (EC 3.2.1.55) and possibly bifunctional xylosidase/arabinofuranosidase activities, similar to Lactobacillus brevis alpha-L-arabinofuranosidase LbAraf43 and Geobacillus thermoleovorans IT-08 beta-xylosidase / exo-xylanase (GbtXyl43B). It belongs to the glycosyl hydrolase clan F (according to carbohydrate-active enzymes database (CAZY)) which includes family 43 (GH43) and 62 (GH62) families. GH43 are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. Many GH43 enzymes display both alpha-L-arabinofuranosidase and beta-D-xylosidase activity using aryl-glycosides as substrates. A common structural feature of GH43 enzymes is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller.	4.96277e-141
NZ_CP047962.1\|WP_161507487.1\|3585940_3586771_-\|hypothetical-protein	gnl\|CDD\|224522	COG1606, COG1606, ATP-utilizing enzymes of the PP-loop superfamily [General function prediction only].	4.64086e-15
NZ_CP047962.1\|WP_161507489.1\|3590524_3591679_+\|hypothetical-protein	gnl\|CDD\|379855	pfam16539, FlgT_M, Flagellar assembly protein T, middle domain. FlgT_M is the middle region of a family of flagellar proteins that make up part of the basal body of the flagellum. The flagellum is a large macromolecular assembly composed of three major parts: the basal body, the hook, and the filament. The basal body has two unique ring structures, the T ring and the H ring. FlgT is required to form and stabilize both ring structures. FlgT-N and FlgT-M are thought to be involved in the H-ring and the T-ring formation, respectively. and FlgT-M is also required for the stable association of FlgT with the basal body.	6.20146e-40
NZ_CP047962.1\|WP_161507863.1\|3591932_3592682_-\|hypothetical-protein	gnl\|CDD\|236481	PRK09360, lamB, maltoporin LamB.	2.95494e-45

>NZ_CP047962.1|WP_019706001.1|3594810_3595758_-|IS30-like-element-ISAs2-family-transposase
MSYQQLTEGQRYQLSVLRAQGMSILATARAIGVHRSTLYRELRRNAGPQGYQPDNAHQHATHRRASAAKSRLSADVIQFVELTLAWWWSPEQISAVGKQIGLMVSHEWIYRHVAADKARGGQLYRHLRQGHKRYRKGASSLRSPIKEARSIDERPAIVDSRERLGDWEADTVLGKQGTGALVTLVERKSRLYLVKRVASKQAGVVRDAIIEMLTPYIEQVHTITFDNGGEFAEHKAIEEALGAETYFAHPYSSWERGLNENSNGLLRQFIPKGTDLREVTDEDVRRAEQWLNLRPRKCLGFRQPVKVFEEYRQAA
>NZ_CP047962.1|WP_012564931.1|3593776_3594724_-|IS30-like-element-ISAeca1-family-transposase
MKYQQLTEGLRYQIACLRDHGLSQARIAKQLGVHPSTISRELRRNCAGQAYQPQQAHQLATARRLTSQKRTVPSDTIDFVCMALVADWSPEQISGVGDMINCPVSHEWIYRYVARDKANGGTLYRHLRQGHKRYRKGKNSKRSVIPNPVSIDERPAIVNERSRVGDWEVDTVLGKQGSGAIVSLLERKSRLYLVQYVPSKTASAVADTIISMLKPYQAHVHTITADNGSEFVEHERVAAELEAQVYFAHPYSAWERGQNENSNGLLRQYVPKGSDLSVVTAEALSAVEKRLNFRPRKCLGFKQPQVVFDELLKAA
>NZ_CP047962.1|WP_005323562.1|3592766_3593684_-|IS5-family-transposase
MGKSKHKISNWKQYNQALVQRGSLTVWMDEQAIQQWHCQTHHGRRGRGFHYSDSAIETALMLKAVFKLPLRALEGFINSLFELMNVPLQSPDYSCISKRAKTVEIKYRLPSHGPVAHLVIDATGLKVYGEGEWKIRKHGKEKRRVWRKLHLAVDAATHAIVAAEVSLETVGDNEVLPTLLNPLRRKIEQVSADGAYDTRACYALLQKKGIKATIPPRKNAAFWKKGHPRNEAVAALKAGELEQWKKDSGYHQRSIAETAMYRFKQLIGPKLSLRSYNAQVGEILAGVKVMNKVIGLGMPIRQAVN
>NZ_CP047962.1|WP_161507863.1|3591932_3592682_-|hypothetical-protein
MGTDTQHSKHQINANNLELTYDSLPLWEGGSLALGYKFLNADPSADQVDEPGSGEHDYSDGHAFMVELNQAVAGTGFNKTVLQYYVDGSAAQGVLMGAADTLNGNVKSGSGYAIRNYGSIPLGDRWDLSHAINYAAADSIETWDNDQLDATMFGASAKLAYHWSEITRTYAEVGYFADEKTENGADYDRSGSKYTVAQAWSLGRNQPELRLYASYFDSDNDNWSDSSHAFEGDDSDDTWVVGVQANVWW
>NZ_CP047962.1|WP_161507489.1|3590524_3591679_+|hypothetical-protein
MKVVLLSTLLLASLSARAELIEAQGSAAILGGDEIYAREQATRDALRQALLASGASVSSIQRLENGSLRSEQIQIRSGGDIRQYRLKREEVRNGRMYITLVADIQAERQICQTQHYAKDLTLVRLRMRYPDQASTGALDDMPADLSRRLFETLAAAPQGVVARQWLDENLRIDPLHLQQGDRSALEEIKALSLRTDSQYLVLGSIDDLSLEPQGNQLTSWYEDPIRNFRMQLYLFDVINGSLLGRKEYQGRANWTFSKREQVGSHNGRFWQSSYGQEVSYQLKEAAQDIVAELACAPVTARIVAQHERGPHISLGRRNGVKLGDQFRVQHSADFIDPYGKSRVMRNPADGLFEVVQVFEDGAIISSQNKYSPFNVQIGDLAVLE
>NZ_CP047962.1|WP_005332494.1|3589619_3590240_-|hypothetical-protein
MNRIITALAVALALAGCGSADPINREQGDPRQAAKGMELNWLVARMTDQLMERKSLTTLSEPIAVASFVDLDTLKDTNWMGLQIEESFIYELNRRGEVVVDFKTTGSIQVTPSGDFVMSRNYKDLSARLPISRILTGTFSRNSQGILVNARIIDLRTKMVETTAQSLIPQQYLSGASNSFGRASVNRGYLMRGGQSASGHLVNLTP
>NZ_CP047962.1|WP_042650348.1|3589173_3589599_-|hypothetical-protein
MRIVLGLMMALLLTACSGNRVVNYDQGEKPDDFPVLKAVGYAVIDIQPGPSQSEKMLQAIRASKMDAYRELAEQLNGQQVRGQSSYKDLTQTSNSLDVSVAGMVRGARVVATYPRGNTYATELELDTRNLYHLNQLMAGQF
>NZ_CP047962.1|WP_025328009.1|3587844_3589017_+|prephenate-dehydratase
MATLDEIRQDITQLDQELLALLAKRKTLSIEVARAKQANPRPIRDTQREQDLLVALIQKGRALGLDAQYITRIYHTIIEDSVLSQQAYLQSLLNPQQQEPMTSVAYLGPRGSYSSLAARKYLARYKDQVIEVNCQNFREVLDTVESGRAAFGVLPIENTSSGSINEVYDVMQHTTLSIVGELTYPIEHCILTAVPTELSRIKTFYAHPQVFQQCSHYLSKLEGARHEICDSSSSAMMKVKELASPDAAAIGSAAGGELYGLDVLAEQLANQKENYSRFIVVARKPIDVAPQIPAKTTLIMSTSQKPGSLVEALLVLRSHEINMTKLESRPVQGNPWEEMFYLDVSANLQTPEMQAALLELTKITRYVKVLGCYPSEDVKPTAVPPVLMGS
>NZ_CP047962.1|WP_161507488.1|3586919_3587519_-|HAD-family-phosphatase
MAIIFDLGRVVVSWDPVGIVRSVRGPDGTEALAERLFNHPDWLEVDRGTLSLHAMASQAEARTGLSMAENLAILQAVPASLLPDPAMVSLIETLHRAGHRLYALSNMGHASIDWLEQHQEFWRFFSGKVVSARVRMIKPEPDIYRYLLVSFDLKAGECLFIDDSPANVAAAQALGLQGMVFTDAAACRRQLVEQGWLPA
>NZ_CP047962.1|WP_161507487.1|3585940_3586771_-|hypothetical-protein
MDANVVALNRGYDQNFQAREQRLISTLAGYGELLVSFSGRLESCYSMDLCRASGVRFRAITLDNPTLSRKAVARAKRYCQHYGIAHQVIKTDEMIFSVHLGHLAEVMDPVRYLCQQLEHGDGPPLLMSASVEEMQEYLRRFDSVPANTLWLFGEQGMTNRDFRYGFHKRQLALWGAGGEACLSQRFSDIESLDRRHLRMVDMAEQMLFDMGLDGAQVFFHTLADRVTTLARIRVPQRMRALVFDMQPNIQKALQSAQFDLVTLDLVSGEDPQLLVI
>NZ_CP047962.1|WP_161507490.1|3596863_3597826_-|family-43-glycosylhydrolase
MPAQASSTFTNPILGDGADPWVVRHDDGFYYYTQTTGSDITLWRTKDITDLENAERKVVWMPAQGAVNGTHLWAPELHLLDGRWYIYFAASDGDMARQRMYVLQSKGVDPFGEYAFPAGTQEGKMADASDKWAIDGTVLDYRGERYFIWSGWEGEVNDQQRLYIARMASPWQLAGPRVEISRPELAWERIGTPQVNEAPQALLSPGGRLFLTYSASGSWTDDYCLGLLALEGEDPMNPAHWRKRPQPVFRKDEALGVYGPGHNGFFIDDGGRPWLIHHAAKFKGAGWNREIHLQPLDWDARGLPSFGLPVGTSRQQMAPR
>NZ_CP047962.1|WP_005328684.1|3597942_3599043_-|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC
MSSVSLKHIKKTYPNGNAVIHGVDLEIEQGEFVVFVGPSGCGKSTLLRMIAGLEDISAGDLHIGNLRANELDAAKRGVAMVFQSYALYPHLTVAENMGFSLLFNNTPKAEIETKVNRVAETLQLAHLLERKPAELSGGQRQRVAIGRAIVREPEVFLFDEPLSNLDAALRGQMRTELARLHQKLGTTMIYVTHDQVEAMTLGDRIVVFNKGHIEQVGSPLDLYQRPATEFVATFLGMPKMNMLTCKLKGKDGDLWQLTPGKGIEVTASESWFDCTGQSNIKIGIRPEHLLVGVEGAPEAHLHGRVSLVENLGDAAILHIKCEGIERLLLAKVNTDRRVPSCDEAVSLTVALEYIHLFGEQGQSLRR
>NZ_CP047962.1|WP_041206300.1|3599115_3599943_-|carbohydrate-ABC-transporter-permease
MNSKLTFTALLAITLTVLLCLLWGAPLLWAISTALRPEAQTVAGLQWLPDPVIFDAFIKVLTMGDLPVFFMNSVVTSLAVTLVTLLITVLAAYSFSQLRFKGANLLFWCCMFGIIFPFEALVIPLFRQVYHMGLADSLGGIILPQVVSPMVLFVLKRFFDQIPKDFREAAILDGAREWQVLLRVYLPLSRNIIYAMAIITFMGAWNNFLWPFLVVSSTENMTIPIGLTQLNDTYGVRYAQNMASALIGGLPVAILYVMFQKRVASGFLAATGLKG
>NZ_CP047962.1|WP_050504416.1|3599944_3600835_-|sugar-ABC-transporter-permease
MDNKDTARTTAGRFGALMTPWLMLAPFLLAFLLFFVIPALQTLQLSFTDSGLTETHGYVGFANYVELLQDPSFWDSLLQTAYFALLTVIPLTALGLVMAMLICRLTRFAGLVQAIFFIPNILPIAVMAMIGGWMLHPTFGVVNLVAGTEIAWFNDPDFAMPMVAIATIWWTVGFNVLLFMAALKNIPQDLYEAARLDGASEWGIFRYITWRQLRPVTVMVFGLQLVASLKIFGQTYLLTGGGPFDSTKVVLHYMYETGFVNQNAGYASAIAVVFVLIVLLILVLQSLANRFINRRG
>NZ_CP047962.1|WP_005328673.1|3600901_3602185_-|extracellular-solute-binding-protein
MKKIKLLALLVAGATLSPITLAQTTLQYWTLLNGGDGARMKQLVDGFNASQGDYKIETTTLNWGEPFYTKLKTASAMGSGPDMATIHLSKISGLTQTQGLEPINPEVLKQAGYDSNQLFPLLWKQSNVDDKTYALPIDTHAMVLYYNKRIAAKAGLLDEQGRLKPIASLAQFDAALKSVKEQGAMGLSMETSPMSYMPYRLWLSMISQQGGKTIENNEFVYGEAGKQAMAAMARWYADGYATKGLDYASSTTEFMTGRSAFMLNGVWELPSVTDGMKSGKLGFEVGIASLPSFFNGSRAAWADSHALAIPRNKDKPISDEKVLGIAKFANYINQNALTWAEGGHIPAYEPTVATQAFKEMPLLADYVSETASNIVYDPDGWYSGAAGPLQATASKYFPAALTGQLPIEKALQMFERDAGKFMSRPAR
>NZ_CP047962.1|WP_161507491.1|3602251_3603328_-|cellulase-family-glycosylhydrolase
MAVQQWSTEQAWQWWSKQPWLRGFNYLPRTAVNWTEMWQRETFDLPTIRQELAWAREVGYNTLRTNLPFIVWQVDRDGLIARIDDFLAVAAAEGISVMLTPMDDCGFSGDHPYLGPQKEPVENLHNSQAAASPGRNVVMDITQWCELERYIKDVVGMFAQDERILVWDLYNEPTNRGIFRGPNQHEEFDPAMELYSHHLMELAFSWAREANPCQPLTVCAWHAANHFSPDDPIFTHPTDLRAMALSDVISFHAYQSLELLEKSLEIVATYDRPLLCTEWLARHAKSFMHEQLPIFKERKIACYQWGLVKGRTQTHLPWPNIQRAVPEFADTWFHDLLEADGSPYDEREVALIQSLTTE
>NZ_CP047962.1|WP_161507492.1|3603630_3603798_+|LacI-family-transcriptional-regulator
MDKQRITMSAIAAVAGVSQSTVSLVLNGSSAVKLSFRGNSGGRPTTYGWRDIARP
>NZ_CP047962.1|WP_161507865.1|3603842_3604166_+|substrate-binding-domain-containing-protein
MREAYEQTRQLLALPNTPDVVFCCSDYMTQGCYQAIAEAGLRIPEDILVAGHDNQMLANEMVPLCLLDAPNEIHKATHDFHLIPVPSRHFASVPSPALDYTLDVGRR
>NZ_CP047962.1|WP_161507493.1|3604162_3605032_+|polyphosphate-kinase-2
MTTTILHWLASREGNHGQQKKSTTEQPAPAAESKPLGNKAYEKELRRLHVELVKLQQWVVHKGLKVCIVFEGRDGAGKGGTIKAITERVSPRVFRVIALPAPTEREKSQLYFQRYIPHLPAAGEIVIFDRSWYNRAGVERVMGFCSQEASDKFLAGVPMVEQAMVDSGIILLKYWLEVTPQEQERRLRDRIDDGRKIWKLSPMDIKSFDRWDDYTLARDAMFTATDTAWAPWFVARSEDKKRVRLNIISHLLAHVPYEELPAEPVKLPKRKIGKVKASEHPFRVIPELF
>NZ_CP047962.1|WP_081934583.1|3605305_3606946_-|SulP-family-inorganic-anion-transporter
MSSPALAPRRSLSDLLAGVTAAAVVLPKAMAYASVAGLPVAIGLYTAFVPMVLYALLGSSRVLSVSSTSTLAILTATQLGLVVPDGDPGRLITVTATLTLLVGAMLMLAAVLRLGFVANFISLPVLVGFKSGIGLVIILDQLPKLFGVHIQKENFFLDLYHLGLALPQTSWLTLGVALVTLVVLVFMEWRFPHSPAPLLGVGIGIALVWGFGLNEAGVAIVGSIPTGLPGLTMPDLTLVLQLLPGAAGIALMSFTETIAAGRAFVGKEEPEINPNRELVATGLANLGGAFCGSMPAGGGTSQTAVVRSVGGVSQWASAVTAAMALATMIFLAPLLSWLPSATLAVVVIVYSVGLIQPGEFRKIGQIRMMEFRWAAIACLGVLLFGTLEGIVVAILASLLGLASQTAQPPVYVIGRKPGEDVLRPLAARHPDDETVPGLLILRPEGRLFFINVQHVAAQIRELIETHQPEVVVLDMSRVQDVEYSALMMLMEGEQQARARGVTLWLAGLNPGVLENVRRSGLASQLGESRMLFNARAAIRQYQQGRE

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Crispr_ID: NZ_CP047962_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047962_7

4206609-4206704

Orphan

Consensus_repeat	Method
ACGTGCTCGGCCGGGCCCGTCAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP047962_7

>merge|NZ_CP047962|7|4206609-4206704|CRISPRCasFinder
ACGTGCTCGGCCGGGCCCGTCATATGCTCGACTGGCCCGCTCACTGGCTTACAGCTCTATCTGGCCATCAAAGACATGCTCGGCCGGGCCCGTCAT

>NZ_CP047962|7|7|4206609-4206704|CRISPRCasFinder
ACGTGCTCGGCCGGGCCCGTCAT	ATGCTCGACTGGCCCGCTCACTGGCTTACAGCTCTATCTGGCCATCAAAG
ACATGCTCGGCCGGGCCCGTCAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047962.1\|WP_161507595.1\|4202850_4203621_+\|gamma-glutamyl-gamma-aminobutyrate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|336781
NZ_CP047962.1\|WP_005330961.1\|4210194_4212714_-\|class-I-adenylate-cyclase	unknown	unknown	gnl\|CDD\|236522
NZ_CP047962.1\|WP_041206763.1\|4204871_4205828_-\|tyrosine-recombinase-XerC	unknown	unknown	gnl\|CDD\|234698
NZ_CP047962.1\|WP_005327739.1\|4197805_4198969_+\|competence-protein-CinA	unknown	unknown	gnl\|CDD\|179629
NZ_CP047962.1\|WP_043130633.1\|4217168_4217420_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|308985
NZ_CP047962.1\|WP_043130614.1\|4201675_4202485_+\|sugar-phosphatase	unknown	unknown	gnl\|CDD\|182509
NZ_CP047962.1\|WP_161507596.1\|4204114_4204825_-\|HAD-IA-family-hydrolase	unknown	unknown	gnl\|CDD\|182696
NZ_CP047962.1\|WP_161507872.1\|4199932_4201561_+\|DUF342-domain-containing-protein	unknown	unknown	gnl\|CDD\|377177
NZ_CP047962.1\|WP_161507597.1\|4205820_4206501_-\|DUF484-family-protein	unknown	unknown	gnl\|CDD\|225701
NZ_CP047962.1\|WP_005330957.1\|4209134_4209449_+\|iron-donor-protein-CyaY	unknown	unknown	gnl\|CDD\|274572
NZ_CP047962.1\|WP_161507598.1\|4207583_4208834_-\|diaminopimelate-decarboxylase	unknown	unknown	gnl\|CDD\|273415
NZ_CP047962.1\|WP_025325500.1\|4208854_4209061_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|338858
NZ_CP047962.1\|WP_042649021.1\|4209463_4210117_+\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|334855
NZ_CP047962.1\|WP_161507873.1\|4214012_4214747_+\|uroporphyrinogen-III-synthase	unknown	unknown	gnl\|CDD\|235647
NZ_CP047962.1\|WP_041207133.1\|4213036_4213966_+\|hydroxymethylbilane-synthase	unknown	unknown	gnl\|CDD\|234612
NZ_CP047962.1\|WP_005327731.1\|4198976_4199492_-\|membrane-protein	unknown	unknown	gnl\|CDD\|183256
NZ_CP047962.1\|WP_161507599.1\|4214743_4215820_+\|heme-biosynthesis-operon-protein-HemX	unknown	unknown	gnl\|CDD\|377333
NZ_CP047962.1\|WP_041204871.1\|4196539_4197778_+\|HD-GYP-domain-containing-protein	unknown	unknown	gnl\|CDD\|225116
NZ_CP047962.1\|WP_005330966.1\|4215830_4216994_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|273126
NZ_CP047962.1\|WP_005327724.1\|4203617_4204022_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP047962.1\|WP_161507595.1\|4202850_4203621_+\|gamma-glutamyl-gamma-aminobutyrate-hydrolase-family-protein	gnl\|CDD\|336781	pfam07722, Peptidase_C26, Peptidase C26. These peptidases have gamma-glutamyl hydrolase activity; that is they catalyze the cleavage of the gamma-glutamyl bond in poly-gamma-glutamyl substrates. They are structurally related to pfam00117, but contain extensions in four loops and at the C-terminus.	9.76404e-89
NZ_CP047962.1\|WP_005330961.1\|4210194_4212714_-\|class-I-adenylate-cyclase	gnl\|CDD\|236522	PRK09450, cyaA, class I adenylate cyclase.	0
NZ_CP047962.1\|WP_041206763.1\|4204871_4205828_-\|tyrosine-recombinase-XerC	gnl\|CDD\|234698	PRK00236, xerC, site-specific tyrosine recombinase XerC; Reviewed.	3.23965e-157
NZ_CP047962.1\|WP_005327739.1\|4197805_4198969_+\|competence-protein-CinA	gnl\|CDD\|179629	PRK03673, PRK03673, nicotinamide mononucleotide deamidase-related protein YfaY.	1.75627e-88
NZ_CP047962.1\|WP_043130633.1\|4217168_4217420_-\|hypothetical-protein	gnl\|CDD\|308985	pfam03692, CxxCxxCC, Putative zinc- or iron-chelating domain. This family of proteins contains 8 conserved cysteines. It has in the past been annotated as being one of the complex of proteins of the flagellar Fli complex. However this was due to a mis-annotation of the original Salmonella LT2 Genbank entry of 'fliB'. With all its conserved cysteines it is possibly a domain that chelates iron or zinc ions.	0.00258313
NZ_CP047962.1\|WP_043130614.1\|4201675_4202485_+\|sugar-phosphatase	gnl\|CDD\|182509	PRK10513, PRK10513, sugar phosphate phosphatase; Provisional.	5.48069e-105
NZ_CP047962.1\|WP_161507596.1\|4204114_4204825_-\|HAD-IA-family-hydrolase	gnl\|CDD\|182696	PRK10748, PRK10748, 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase YigB.	3.10975e-58
NZ_CP047962.1\|WP_161507872.1\|4199932_4201561_+\|DUF342-domain-containing-protein	gnl\|CDD\|377177	pfam03961, FapA, Flagellar Assembly Protein A. Members of this family include FapA (flagellar assembly protein A), found in Vibrio vulnificus. The synthesis of flagella allows bacteria to respond to chemotaxis by facilitating motility. Studies examining the role of FapA show that the loss or delocalization of FapA results in a complete failure of the flagellar biosynthesis and motility in response to glucose mediated chemotaxis. The polar localization of FapA is required for flagellar synthesis, and dephosphorylated EIIAGlc (Glucose-permease IIA component) inhibited the polar localization of FapA through direct interaction.	1.87506e-144
NZ_CP047962.1\|WP_161507597.1\|4205820_4206501_-\|DUF484-family-protein	gnl\|CDD\|225701	COG3159, COG3159, Uncharacterized protein conserved in bacteria [Function unknown].	1.83059e-37
NZ_CP047962.1\|WP_005330957.1\|4209134_4209449_+\|iron-donor-protein-CyaY	gnl\|CDD\|274572	TIGR03421, FeS_CyaY, iron donor protein CyaY. Members of this protein family are the iron-sulfur cluster (FeS) metabolism protein CyaY, a homolog of eukaryotic frataxin. ISC is one of several bacterial systems for FeS assembly; we find by Partial Phylogenetic Profiling vs. the ISC system that CyaY most like work with the ISC system for FeS cluster biosynthesis. A study of of cyaY mutants in Salmonella enterica bears this out. Although the trusted cutoff is set low enough to include eukaryotic frataxin sequences, a narrower, exception-type model (TIGR03421) identifies identifies members of that specific set. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	1.62031e-54
NZ_CP047962.1\|WP_161507598.1\|4207583_4208834_-\|diaminopimelate-decarboxylase	gnl\|CDD\|273415	TIGR01048, Diaminopimelate_decarboxylase, diaminopimelate decarboxylase. This family consists of diaminopimelate decarboxylase, an enzyme which catalyzes the conversion of diaminopimelic acid into lysine during the last step of lysine biosynthesis. [Amino acid biosynthesis, Aspartate family].	0
NZ_CP047962.1\|WP_025325500.1\|4208854_4209061_-\|hypothetical-protein	gnl\|CDD\|338858	pfam13627, LPAM_2, Prokaryotic lipoprotein-attachment site. In prokaryotes, membrane lipoproteins are synthesized with a precursor signal peptide, which is cleaved by a specific lipoprotein signal peptidase (signal peptidase II). The peptidase recognizes a conserved sequence and cuts upstream of a cysteine residue to which a glyceride-fatty acid lipid is attached.	0.000122754
NZ_CP047962.1\|WP_042649021.1\|4209463_4210117_+\|alpha/beta-fold-hydrolase	gnl\|CDD\|334855	pfam02230, Abhydrolase_2, Phospholipase/Carboxylesterase. This family consists of both phospholipases and carboxylesterases with broad substrate specificity, and is structurally related to alpha/beta hydrolases pfam00561.	2.04312e-35
NZ_CP047962.1\|WP_041207133.1\|4213036_4213966_+\|hydroxymethylbilane-synthase	gnl\|CDD\|234612	PRK00072, hemC, porphobilinogen deaminase; Reviewed.	0
NZ_CP047962.1\|WP_005327731.1\|4198976_4199492_-\|membrane-protein	gnl\|CDD\|183256	PRK11648, PRK11648, metal-dependent hydrolase.	6.69136e-66
NZ_CP047962.1\|WP_161507599.1\|4214743_4215820_+\|heme-biosynthesis-operon-protein-HemX	gnl\|CDD\|377333	pfam04375, HemX, HemX, putative uroporphyrinogen-III C-methyltransferase. This is a family of bacterial putative uroporphyrinogen-III C-methyltransferase proteins. It forms one of the members of a complex of proteins involved in the biogenesis of the inner membrane in E.coli. Uroporphorphyrin-III C-methyltransferase (HemX) is a single spanning inner membrane protein that regulates the activity of NAD(P)H:glutamyl-tRNA reductase (HemA) in the tetrapyrrole biosynthesis pathway.	9.19011e-96
NZ_CP047962.1\|WP_041204871.1\|4196539_4197778_+\|HD-GYP-domain-containing-protein	gnl\|CDD\|225116	COG2206, COG2206, c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms].	4.48404e-54
NZ_CP047962.1\|WP_005330966.1\|4215830_4216994_+\|hypothetical-protein	gnl\|CDD\|273126	TIGR00540, TPR_hemY_coli, heme biosynthesis-associated TPR protein. Members of this protein family are uncharacterized tetratricopeptide repeat (TPR) proteins invariably found in heme biosynthesis gene clusters. The absence of any invariant residues other than Ala argues against this protein serving as an enzyme per se. The gene symbol hemY assigned in E. coli is unfortunate in that an unrelated protein, protoporphyrinogen oxidase (HemG in E. coli) is designated HemY in Bacillus subtilis. [Unknown function, General].	6.86241e-79
NZ_CP047962.1\|WP_161507873.1\|4214012_4214747_+\|uroporphyrinogen-III-synthase	gnl\|CDD\|235647	PRK05928, hemD, uroporphyrinogen-III synthase; Reviewed.	5.71339e-63

>NZ_CP047962.1|WP_161507597.1|4205820_4206501_-|DUF484-family-protein
MSELKRQESLLDEATVLEYLARYPEFFQRHGAMLDRIRIPHEHKGTISLVERQLDRQRERIEQLEQEITELMGIASENERIFRVYADLYGELYGCQTLFELSAVMGKAFVQRLRLTGLRLWLSPKKFQLTGPEQRFLADGKQLDQLLGQRLPGTDYYFGRLNQSEKQALFGSDVLVNSVALMRLGDLGVLAFASSDPSHFTPHNDTLLLGQLGRLLQMRLPELVRG
>NZ_CP047962.1|WP_041206763.1|4204871_4205828_-|tyrosine-recombinase-XerC
MAKAPLPAADPLPPALAGELTAFIEYLRVERQLSPHTRSNYQAHLEAMAAELVRLGVDDWARLEASQVRSLVTRMHKAGLAPRSLATKVSALRSFCDWQVRQGRLPANPARGIVTPKQGRPLPKNLDVDEMYQLLNITDEQDPLAVRDRAIMELMYSSGLRLAELVGLNLADVKLDERQLRVTGKGSRERVLPMGRMAVEWLHKWLKVRPALAGDEGEALFVSKRRQRLSARSVQERLDGWGNKQALNAHVHPHKLRHSFATHMLESSGDLRAVQELLGHADLSTTQIYTHLDFQHLAKVYDSAHPRAKRDPDTPEDE
>NZ_CP047962.1|WP_161507596.1|4204114_4204825_-|HAD-IA-family-hydrolase
MHFYRRWQPVAAISFDLDDTLYDNGPAIARAEQWMLSHLRSEYLATAMLDKPRWLELKRNLLLARPELGQDVSLARQHGIREAMVQGGMAASLAEQEAQRVFAGFLAERSKIAVSESTHRLLTRLAERYPLAVITNGNLDLVQAGLSDYFTLVCKAGAGARMKPAPDMFVQVQQTLGLAPGQILHVGDHPETDVLGARLHGFRAAWLNERRLPWQSLRLLPDVELATLDELDGLLL
>NZ_CP047962.1|WP_005327724.1|4203617_4204022_-|hypothetical-protein
MKSVIWLAIPMVLAGCDLFRDHYRMEFRDGSWRDIAISPFSDEARWREGCATGEILVDMTLPLKRGKVVDGREQLLIGGELFELEEARLYRGNGMVLGQAPDHVQRGLKGLDVCRTLRPDRGALPKLKGKGFGD
>NZ_CP047962.1|WP_161507595.1|4202850_4203621_+|gamma-glutamyl-gamma-aminobutyrate-hydrolase-family-protein
MPNPSSHSKPVVLMTMGAQARSGHAYQVMTHKYITPLVEISGCVPLLVPTCCGTADLEQYLDLADGVYLSGAGSNIDPALYGQENLTPEKAQDRDRDLFDIALVRAAIDRGLPLLGICRGMQEINVALGGDIHQKVYCEPGYADHREDADDPVEEQYGHSHQVSLVPGSWFADLMGEAQIPVNSLHGQGIKRLGKGLAPLAHAEDGLIEAIHAPGLPQFTLAVQWHPEWKAKENPHSIKLFRAFGDACRQYRQRAG
>NZ_CP047962.1|WP_043130614.1|4201675_4202485_+|sugar-phosphatase
MYKLIALDMDGTLLNPHGQITPRTHAAIAAARTQGVTVVLTSGRPLEGMTTYLAELGLTGQDDYVICYNGALVQQVADQRILRSQLLTGSDASAIAHLAFELGVNVHGFSVRQGLISPRVSTYTEHESRLIKMPINLVDFATLPADEQIMKVMMIDPEPQLSRAIAQLPAELYERYTVVRSSPYFLEFMNKRSNKGTGVAALAEHLGLDASQVIAVGDAGNDRHMIEYAGLGVAMGNATDEIKALAQHTTARNDEDGVARVIEQFILNA
>NZ_CP047962.1|WP_161507872.1|4199932_4201561_+|DUF342-domain-containing-protein
MTYVCLRIAPGLTDLVQEHHVLALLRLSNCRRYQPLGEGIRQAVTLLNTLLTQPDAPSHPPVPIAQRQDARLLILIDKDQMSASAQITADWGGSSLTLAQLQEAVAASPVKQGVSERLLAAAIKAASEAAPGTRLNPVIALGKAARHGLDTRLERLVETAAERILKPQELDHGRVDMRDLGTLLTVKAGAPLMQRHPATQGIDGFTVTGQVLAARSGKESAMTAGEGTCFSPEDPDLLLATRAGLPCQERAGMRVDEVLSVKQVDIRHGHVEFEGSLLVTGDVMPGMRIKTSGDVVIGGFVEGGYIESGGTITVRNGIIGRKLEGDEYLCHLCAGGEIHASYAQYARLEADGDIHIQSQLSHSYCRSGQDLKVGDSAMRKGHLIGGINIANRLIMAPVLGASAANRTRLQILGGYFSHKEQEQALRQRKQACREQLDKLQDLILRLLQQPSDKRNPETLKKIKAIRTHQLDESKSLDEQLAEAQHALQALMASMDIIATQRLFPGVEVEMAHYHSRVDIEHGPIHFAIRDEQLQLTPYEGQR
>NZ_CP047962.1|WP_005327731.1|4198976_4199492_-|membrane-protein
MTAQGHLLFSVTCALLAHKVELTPALAEGSLWHIVPMALASALLPDLDHPQSLLGRQLPWISGPLSRLFGHRGFTHSLLAVGLGIWGLAQFQVSGPLSGVMKDALIVGYLSHLLGDWLTPMGIPLLWPWRRRFRLPGLPLKSGGGYEKAFCLLTLALAGYWVHGNGGLGAF
>NZ_CP047962.1|WP_005327739.1|4197805_4198969_+|competence-protein-CinA
MRIEIISTGDEIVTGLVVDTNAAWLSALLLEQGWQVRRRLTVGDNLADLKAALQESASRAEVVLVCGGLGPTADDLTAQAAAEAFGQPLTLFPDWLATMAERYASRGRTMAQSNTKQAWLPRDCEILDNPVGTACGFVVNHPASHGQSRLFFTPGVPFEFKQMVREQILPRLKALAGEETDTELRRFYTFGISESALSDKLDAAPWPASIELGYRSSMPLIELKLIGHGASAADMDAAEARLLGEITPWLVGQGNEEPAQQILSLLGARPLYLQEGESRGALLAMCHPHPGLEASFSHCLPCELDQLTGCGQEPCLTIGSAGPGGVPLLLCADGQRIGQQVKLSHPDPESARRILAFAALDMLRRHLQGLPVLADYLTLTRTASRID
>NZ_CP047962.1|WP_041204871.1|4196539_4197778_+|HD-GYP-domain-containing-protein
MTGIKISVDRLQVGNYVSLPLGWREHPFLFSSFKLKSEEEIELIRRLGLKLVTIIPDKSDAPPKPLDQVQPAPDGSDDLVGRQQEMQQEKTRRIEQLQRYRRDLQQCEKHFQQSLAQVRNLMGKIQSRPLNAINEAQELINAMTEQLLSVDEMVLHLVSDSADGNNLQFHSLNVSVLSMLLARECKLPAEAIRQVGMGALFHDIGKLKIPSQILRKTGPLTKPEQNLMAQHPRYGLELLSLTSGFPEPAKRIVQYHHEYLDGSGPQGLRGDQLDPLTQIVSLINEYDNLCHLQAKVPYSALGNLYKQRKGQFNADHLGMLIRLMGIYPPGSVVQLSNGQVGLVMSVNASRLLYPAVLVYDPRIPRQEAAIIDLEQAELTIAKVIHPKRLPPAVFEYLNPRTRISYYFEHNKP
>NZ_CP047962.1|WP_161507598.1|4207583_4208834_-|diaminopimelate-decarboxylase
MDHFNYDADGQLQAEQLPLQQLADQYGTPLYVYSRATLERHWHAFDQAAGDIPHLICYAVKANSNLALLNLLARLGSGFDIVSGGELSRVLAAGGDPAKVVFSGVAKSEAEMRLALEKEILCFNLESEAELERLNRVAGSMGKKARVSVRVNPDIDAGTHPYISTGLKQNKFGIPIEQAPAIYRKAAAMTHIEIKGVDCHIGSQLTELNPFMEAADKLLKLIDELAAEGIHIHHLDVGGGLGVNYGAEQPPHPTEYAEALKQKLAGRDLTLLFEPGRAIVANAGVLLTRVEFLKPGETRNFALIDAGMNDLLRPSLYGAWMNIIEVDSRTTHEKALYDVVGPVCETGDFLGKERTLAIAEGSLLAVRSAGAYGFTMSSNYNTRPRAAEVLVDGDQAHLIREREQLADLWRGEHLLP
>NZ_CP047962.1|WP_025325500.1|4208854_4209061_-|hypothetical-protein
MITQFTKCLFAASLSFGLAACGLTGPLYMPPAEQPVSTEQTPAQPKTESTPQAASPATAKPASEAAPQ
>NZ_CP047962.1|WP_005330957.1|4209134_4209449_+|iron-donor-protein-CyaY
MKDHEYHALTDAFFQYVEDVIDEGYPDIDCERAGGVLTLSFENKTKVIINKQEPLHQIWVATRENGFHFELRGDSWIDNRFGDELKALLTRACTTQAGEPVRFP
>NZ_CP047962.1|WP_042649021.1|4209463_4210117_+|alpha/beta-fold-hydrolase
MMDLHPQGARHAVVWLHGLGDSGAGLAPLVEALALPTDLPVRHLLPDAPERPITINMGYKMRGWYDIKSFEDPADRAVESHVRESADRIAALLDQLVAEGFAPEHIVLAGFSQGGVIASFTALRYQAKLAGLLCMSTYLAAPEQLVEEMSEAARALPICYMHGIYDDVVSLSMGWDAKNRLEAAGLSPEWHEYPMRHEICRPQLDEIRRWLLARLGA
>NZ_CP047962.1|WP_005330961.1|4210194_4212714_-|class-I-adenylate-cyclase
MLVKLDTLVARYDELNRLKTQRALDLMSRYGQQVFQLLPVMLHFNHPLLPGYVAGDVPHGIWSFVANEAQQAFIHDLCQNANCQGGLSTHDKSIQGLYSMGSTSSIGQCCHSDLDIWVCHVAGLSSERLALLEQKCQHLSLWAEQRGVDLNFFLIPEDKFRQRNDAQMQGESCGSAQHLLLLDEFYRSAMHIAGKRLLWYLVPAEYDDHYDDYVNGLFAHGKLSQDDWLDLGGFDRIPAEEYFGSALWQLYKGIDSPYKAVLKSVLMEAYSHEYPNTRLLSVTSRDWFQHNEGMHYRLDNYCLMLDKVTNYLKSIGDMQRLDLVRRCFYLKVCDGLSHPKEDHSPDWRREQMAQLVAYWGWSPERLHHLDHRQEWKVEDVKVAYAELLEALMQSYRNLIQFARRNNISESINPEDIGILSRKLYAAFESLPGKVQRINLKIAPDLGEPDLSLVQVPHGRLNRAGWYLYKHSLEPADIIGRAPLEYNGYISKLVAWAYFNGLLTPQSRVHLFNQGSDLHIDNLHQFCRDLSGTFPVKYPRATNLALSRPCEIRQLSIFLNLETDPSSHWVGQVIEFDANAADVFSFGRNQECLVGSVDLVYRNSWSEIRTLHFEGEEAVVDALTTILGKMHQDAAAPEMIEVFCYSQHFRSLVRTRFQQLVAECIELRLARDKQQLVKTLALGKEKYGIFFERRGVSVKKLENAIDFYRHISHNKLDHLPLRLDKTHSQHLPGIVDAYASEGLVQFFFDTRDAGTNIYILDEANRVEIYQHFAGNKDELVQGVNRFYTSGHERFSDAGQFSNFNLPQYYEIVQMGDKLEVIPYRSQSPQRDNPGAAREVG
>NZ_CP047962.1|WP_041207133.1|4213036_4213966_+|hydroxymethylbilane-synthase
MAARTLRIATRKSPLALWQANFVKDRLEALYPDLRVELVPMSTQGDKILDTPLAKVGGKGLFVKELETAMLEGRADIAVHSMKDVPVEFPEGLGLHTICEREDPRDAFVSNRFKQIDELPQGAVVGTSSLRRQCQLRAARPDLVIRDLRGNVNTRLAKLDAGEYDAIILAAAGLKRLEMAHRITAFIEPEQSLPANGQGAVGIECRLDDVELHALLAPLEHAETRIRVLTERAMNRALQGGCQVPIGAYALVQGDEIWLRGLVGSPDGTQVIRDEIRGPLTDGEALGHTLAQRLLADGADAILAEVYRA
>NZ_CP047962.1|WP_161507873.1|4214012_4214747_+|uroporphyrinogen-III-synthase
MVPLVVRPAAQAAELAALLRQHGHAPLCCPLLETRPGSELPHLPELLPQTDIIIAVSAHAVKFAHHFLLQTGLTWPHIDYFAVGQASADAFSEVGVQALCPTDPRSEGLLALPPLQGVSGKRVLILRGNDGRDLIARTLASRGALVHYCATYERHYPELDGDALTRYWQAAGLDSLLITSGELLQRLLALVPGPQRPWLYDRLLVVPSPRVAEMAEGAGFTRIVIAQGASNQALVAALELRKME
>NZ_CP047962.1|WP_161507599.1|4214743_4215820_+|heme-biosynthesis-operon-protein-HemX
MTEQQEVQPSAAAPAADNNKPENKAASNKKGGAGVVLGGVAILLALGLTGGLYLHGHQNAVAQQAELGALKLQLAEAMGKLDQSNSKDAEQIGALGKNQQQLQEALDALQTKVLDLDDKRPNDWMLAESEYLVRMAGRKLWLEHDIVSAITLLGNADERIKALNDPSLMPIRKALAEDIAQLKGMPRVDREGLTLKLAALSDQIELLPLSTVSMPQAKAEPDQAVSANPDEWESNLKKNWVKFTENFITIRRRDGAVEALLSPQQEIFLRENLKTKLLQAQLAVYREQQALYTDSLEKAQRWLTQYFDTDNSATQYMQSELDKLKSEQIQFDYPDQFKTQAMLEQVLTERLQRILAGN
>NZ_CP047962.1|WP_005330966.1|4215830_4216994_+|hypothetical-protein
MIRLIVVVAVMVAGLIFGPEASGNKGYVLISLGNYTVESSVTSAVILAVLFYGALLIVEWVLGRVFGLRRKTQGWFGSRRRRKANLQTVNATLAMAEGHYNQAEKLLIKGADNSDTPLLNYLSAARVAQARGDDVRRDHYLQKAQEENPKAELALTLIQTQLQIEQGQYDSALGRLESVYALHPRHPMVLDQLRQVYLAREDWAALIDLAPALRKVGKLTSVQEEALLHQAWIGRLEAASGALETLRPVWQALPRKLRQDPELLANYGDRLRRLGADSEAADLWLEALRKDPSPELFARLPKLRLDDYQPMLTLLKKIQDQPGAEAALARVYLLAGQLDDAQRLLEQEVAKRPDAALYHALGQVMDKRRLTNKANEYYRQALQLADV
>NZ_CP047962.1|WP_043130633.1|4217168_4217420_-|hypothetical-protein
MECRQGCGACCTAPSISSAIPGMPEGKPAGVPCIQLDAWLGCKIFGQPERPAVCSSFRPMQDVCGSHRQEAVWLIGEMERLTA

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Crispr_ID: NZ_CP047962_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047962_8

4395630-4395738

Orphan

Consensus_repeat	Method
GCATCAACTCCAGACCAAATCGTCCGGGTTGGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP047962_8

>merge|NZ_CP047962|8|4395630-4395738|CRISPRCasFinder
GCATCAACTCCAGACCAAATCGTCCGGGTTGGCCAGGGTGATAACTGTACGCAGCACTCTCATCGGTACCGACCTGGCATCAACTCCAGACTAAATCGTCCGGGTTGGC

>NZ_CP047962|8|8|4395630-4395738|CRISPRCasFinder
GCATCAACTCCAGACCAAATCGTCCGGGTTGGC	CAGGGTGATAACTGTACGCAGCACTCTCATCGGTACCGACCTG
GCATCAACTCCAGACTAAATCGTCCGGGTTGGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047962.1\|WP_161507673.1\|4390146_4390608_-\|transcriptional-regulator-AsnC	unknown	unknown	gnl\|CDD\|183019
NZ_CP047962.1\|WP_161507671.1\|4388666_4389203_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227700
NZ_CP047962.1\|WP_161507672.1\|4389286_4390051_+\|amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|366132
NZ_CP047962.1\|WP_161507668.1\|4386806_4387355_+\|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase	unknown	unknown	gnl\|CDD\|376515
NZ_CP047962.1\|WP_161507677.1\|4396796_4397561_+\|outer-membrane-protein-assembly-factor-BamD	unknown	unknown	gnl\|CDD\|274513
NZ_CP047962.1\|WP_161507679.1\|4399161_4400562_-\|L-cystine-transporter	unknown	unknown	gnl\|CDD\|224736
NZ_CP047962.1\|WP_161507675.1\|4392040_4394614_-\|ATP-dependent-chaperone-ClpB	unknown	unknown	gnl\|CDD\|274529
NZ_CP047962.1\|WP_161507682.1\|4405861_4407025_-\|alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|185092
NZ_CP047962.1\|WP_161507678.1\|4397760_4399089_-\|CoA-disulfide-reductase	unknown	unknown	gnl\|CDD\|181958
NZ_CP047962.1\|WP_139437938.1\|4402333_4403818_-\|Re/Si-specific-NAD(P)(+)-transhydrogenase-subunit-beta	unknown	unknown	gnl\|CDD\|236520
NZ_CP047962.1\|WP_161507670.1\|4388265_4388670_+\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|341392
NZ_CP047962.1\|WP_161507680.1\|4400718_4402011_-\|serine-dehydratase-subunit-alpha-family-protein	unknown	unknown	gnl\|CDD\|226206
NZ_CP047962.1\|WP_161507676.1\|4394785_4395523_-\|peptidoglycan-editing-factor-PgeF	unknown	unknown	gnl\|CDD\|182677
NZ_CP047962.1\|WP_161507669.1\|4387431_4388136_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|180586
NZ_CP047962.1\|WP_161507674.1\|4390762_4391755_+\|aspartate--ammonia-ligase	unknown	unknown	gnl\|CDD\|235456
NZ_CP047962.1\|WP_005324436.1\|4407168_4408071_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|377694
NZ_CP047962.1\|WP_106885551.1\|4386588_4386681_-\|YnhF-family-membrane-protein	unknown	unknown	unknown
NZ_CP047962.1\|WP_161507681.1\|4403829_4405356_-\|Re/Si-specific-NAD(P)(+)-transhydrogenase-subunit-alpha	unknown	unknown	gnl\|CDD\|236507
NZ_CP047962.1\|WP_161507683.1\|4408087_4408600_+\|lipocalin	unknown	unknown	gnl\|CDD\|182489
NZ_CP047962.1\|WP_161507684.1\|4410775_4411294_+\|class-IV-adenylate-cyclase	unknown	unknown	gnl\|CDD\|143628

Protein	Function_ID	Function_description	E-value
NZ_CP047962.1\|WP_161507673.1\|4390146_4390608_-\|transcriptional-regulator-AsnC	gnl\|CDD\|183019	PRK11179, PRK11179, DNA-binding transcriptional regulator AsnC; Provisional.	2.74359e-111
NZ_CP047962.1\|WP_161507671.1\|4388666_4389203_-\|hypothetical-protein	gnl\|CDD\|227700	COG5413, COG5413, Uncharacterized integral membrane protein [Function unknown].	4.30823e-29
NZ_CP047962.1\|WP_161507672.1\|4389286_4390051_+\|amino-acid-ABC-transporter-substrate-binding-protein	gnl\|CDD\|366132	pfam00497, SBP_bac_3, Bacterial extracellular solute-binding proteins, family 3.	9.40279e-23
NZ_CP047962.1\|WP_161507668.1\|4386806_4387355_+\|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase	gnl\|CDD\|376515	pfam01288, HPPK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK).	1.75854e-21
NZ_CP047962.1\|WP_161507677.1\|4396796_4397561_+\|outer-membrane-protein-assembly-factor-BamD	gnl\|CDD\|274513	TIGR03302, OM_YfiO, outer membrane assembly lipoprotein YfiO. Members of this protein family include YfiO, a near-essential protein of the outer membrane, part of a complex involved in protein insertion into the bacterial outer membrane. Many proteins in this family are annotated as ComL, based on the involvement of this protein in natural transformation with exogenous DNA in Neisseria gonorrhoeae. This protein family shows sequence similarity to, but is distinct from, the tol-pal system protein YbgF (TIGR02795). [Protein fate, Protein and peptide secretion and trafficking].	1.48689e-98
NZ_CP047962.1\|WP_161507679.1\|4399161_4400562_-\|L-cystine-transporter	gnl\|CDD\|224736	COG1823, COG1823, Predicted Na+/dicarboxylate symporter [General function prediction only].	0
NZ_CP047962.1\|WP_161507675.1\|4392040_4394614_-\|ATP-dependent-chaperone-ClpB	gnl\|CDD\|274529	TIGR03346, chaperone_ClpB, ATP-dependent chaperone ClpB. Members of this protein family are the bacterial ATP-dependent chaperone ClpB. This protein belongs to the AAA family, ATPases associated with various cellular activities (pfam00004). This molecular chaperone does not act as a protease, but rather serves to disaggregate misfolded and aggregated proteins. [Protein fate, Protein folding and stabilization].	0
NZ_CP047962.1\|WP_161507682.1\|4405861_4407025_-\|alcohol-dehydrogenase	gnl\|CDD\|185092	PRK15138, PRK15138, alcohol dehydrogenase.	0
NZ_CP047962.1\|WP_161507678.1\|4397760_4399089_-\|CoA-disulfide-reductase	gnl\|CDD\|181958	PRK09564, PRK09564, coenzyme A disulfide reductase; Reviewed.	0
NZ_CP047962.1\|WP_139437938.1\|4402333_4403818_-\|Re/Si-specific-NAD(P)(+)-transhydrogenase-subunit-beta	gnl\|CDD\|236520	PRK09444, pntB, Re/Si-specific NAD(P)(+) transhydrogenase subunit beta.	0
NZ_CP047962.1\|WP_161507670.1\|4388265_4388670_+\|CBS-domain-containing-protein	gnl\|CDD\|341392	cd04629, CBS_pair_bac, Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains present in bacteria. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).	6.25548e-55
NZ_CP047962.1\|WP_161507680.1\|4400718_4402011_-\|serine-dehydratase-subunit-alpha-family-protein	gnl\|CDD\|226206	COG3681, COG3681, L-cysteine desulfidase [Amino acid transport and metabolism].	1.09288e-136
NZ_CP047962.1\|WP_161507676.1\|4394785_4395523_-\|peptidoglycan-editing-factor-PgeF	gnl\|CDD\|182677	PRK10723, PRK10723, polyphenol oxidase.	9.82199e-122
NZ_CP047962.1\|WP_161507669.1\|4387431_4388136_-\|SDR-family-oxidoreductase	gnl\|CDD\|180586	PRK06483, PRK06483, dihydromonapterin reductase; Provisional.	1.76603e-70
NZ_CP047962.1\|WP_161507674.1\|4390762_4391755_+\|aspartate--ammonia-ligase	gnl\|CDD\|235456	PRK05425, PRK05425, asparagine synthetase AsnA; Provisional.	0
NZ_CP047962.1\|WP_005324436.1\|4407168_4408071_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|377694	pfam06719, AraC_N, AraC-type transcriptional regulator N-terminus. This family represents the N-terminus of bacterial ARAC-type transcriptional regulators. In E. coli, these regulate the L-arabinose operon through sensing the presence of arabinose, and when the sugar is present, transmitting this information from the arabinose-binding domains to the protein's DNA-binding domains. This family might represent the N-terminal arm of the protein, which binds to the C-terminal DNA binding domains to hold them in a state where the protein prefers to loop and remain non-activating. All family members contain the pfam00165 domain.	7.42583e-50
NZ_CP047962.1\|WP_161507681.1\|4403829_4405356_-\|Re/Si-specific-NAD(P)(+)-transhydrogenase-subunit-alpha	gnl\|CDD\|236507	PRK09424, pntA, Re/Si-specific NAD(P)(+) transhydrogenase subunit alpha.	0
NZ_CP047962.1\|WP_161507683.1\|4408087_4408600_+\|lipocalin	gnl\|CDD\|182489	PRK10477, PRK10477, outer membrane lipoprotein Blc; Provisional.	1.29935e-81
NZ_CP047962.1\|WP_161507684.1\|4410775_4411294_+\|class-IV-adenylate-cyclase	gnl\|CDD\|143628	cd07890, CYTH-like_AC_IV-like, Adenylyl cyclase (AC) class IV-like, a subgroup of the CYTH-like superfamily. This subgroup contains class IV ACs and similar proteins. AC catalyzes the conversion of ATP to 3',5'-cyclic AMP (cAMP) and PPi. cAMP is a key signaling molecule which conveys a variety of signals in different cell types. In prokaryotes, cAMP is a catabolite derepression signal which triggers the expression of metabolic pathways including the lactose operon. Six non-homologous classes of ACs have been identified (I-VI). Class IV ACs are found in this group. In bacteria, the gene encoding Class IV AC has been designated cyaB and the protein as AC2. AC-IV occurs in addition to AC-I in bacterial pathogens such as Yersinia pestis (plague disease). The role of AC-IV is unknown but it has been speculated that it may be a factor in pathogenesis, perhaps providing cAMP for a secondary internal signaling function, or for secretion and uptake into host cells, where it may disrupt normal cellular processes. This subgroup belongs to the CYTH/triphosphate tunnel metalloenzyme (TTM)-like superfamily, whose enzymes have a unique active site located within an eight-stranded beta barrel.	1.50798e-39

>NZ_CP047962.1|WP_161507676.1|4394785_4395523_-|peptidoglycan-editing-factor-PgeF
MNWIEPDWPAPGNVRALSTTRDGGLSEGVFAGLNLGAHVGDEPAQVEANRARLQQAAQIPGPLNWLNQVHGTAVHSVSDQYDVAPDADAACAHEAGQACIVMTADCLPVLFCDRAGTVVAAAHAGWRGLKEGVLEASIAAMGCEPGEILAWLGPAIGPTAFEVGGEVRDAFMAEQSEAATAFVPSSNEGKWLADIYLLARLRLARAGVTAVYGGEYCTFSDGEQFYSYRRNGQTGRMASIIWLAP
>NZ_CP047962.1|WP_161507675.1|4392040_4394614_-|ATP-dependent-chaperone-ClpB
MRLDRLTSKFQVAISDAQSLALGRDHQFIEPVHLMTALLNQDGGSIRPLLTLTGMDINTLRSRLGEELDRLPKVSGVEGDVQLSNGLGRLLNVCDKLAQQRKDQFISSELFVLAALDEKGNLGELLRAQGLTKEKLEAAIDKVRGGKKIDDANAEENRQALEKYTIDLTERAELGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGAPGVGKTAIVEGLAQRIINGEVPEGLKNKRVLSLDMGALVAGAKYRGEFEERLKAVLSDLAKEEGNVILFVDELHTMVGAGKGEGAMDAGNMLKPALARGELHCVGATTLDEYRQYVEKDAALERRFQKVLVEEPSVEDTIAILRGLKERYELHHHVQITDPAIVAAAQLSHRYIADRQLPDKAIDLIDEAAASIRLQIDSKPESLDRLERRIIQLKLEQQALMKEDDDASRKRLDLLNHELAEKEREYNELEEVWKAEKAALAGTQHIKAALEQARQDLEVARRAGDLGRMSELQYGRIPELEKQLDLATQAEMQETSLLRNRVTDVEIADVLARWTGIPVARMLEGERDKLLRMEDQLHSRVIGQEEAVDAVSNAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKALAEFLFDTQDAMVRIDMSEFMEKHSVARLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNLGSDLIQEHYAEKDYEEMKALLMELLTRSFRPEFINRIDETVVFHPLGEDHIKSIARIQLKSLMGRLESQGFEVEVSEELLTKLVHAGFDPVYGARPLKRAIQQKVENPLAQALLSGRVIPGKKLLLGADSNGLTMTQ
>NZ_CP047962.1|WP_161507674.1|4390762_4391755_+|aspartate--ammonia-ligase
MKQHYIRSQQQISFVKEMFSRQLAQQLGLMEVQAPILSRVGDGTQDNLSGHENAVQVKVKTLPEHSYEVVHSLAKWKRHTLGRFGFGPGEGIYTHMKALRPDEDKLTPIHSVYVDQWDWEKVMPSERRDLAYLQETVRGIWAAIKATERAVCAEHALTPFLPSEIQFLHSEELLTRYPDLDAKGRERAIAKELGAVFLIGIGGALSHGERHDVRAPDYDDWSSESELGLAGLNGDILVWNPVLEDSFEISSMGIRVDAEALRRQLAITGDEDRLQYDWHQDLLAARMPQTIGGGIGQSRLAMLLLQKEHIGQVQVGVWPSEMKAAIPGML
>NZ_CP047962.1|WP_161507673.1|4390146_4390608_-|transcriptional-regulator-AsnC
MPENYRIDNLDQAILTALMENARIPYAELAKQLAVSPGTIHVRVEKMKQAGIIEGTRVQVNAKKLGYDVCCFIGINLKSAKDYPSALAKLQALDEVVEAYYTTGHYSIFMKVMTRSIDELQTVLIHKIQTIDEIQSTETLISLQNPILRDVKP
>NZ_CP047962.1|WP_161507672.1|4389286_4390051_+|amino-acid-ABC-transporter-substrate-binding-protein
MRSLLVLCLLLPCWLSARELVIGGILEPPLKWLDHSGQPRGLDVDLVTTIFGGLKVPIRIELLDSGARLTRNAEGGVYDLLLSHSYKPERESYLLYPKQAHIRHSWHFFVRKDDLGKIRYRTLADLEPWRIGVTKDFSYTPELTAAMADPAYRFQVIPINQLQLRKLIAGRIDVVPMSLVTAFAQIREEGLEGKLDYLPKPLKSSPYYHVWCKARADADTPALMAAYDAELLHMKRDGRLKALYDKYGIPYLEP
>NZ_CP047962.1|WP_161507671.1|4388666_4389203_-|hypothetical-protein
MANPEIESELDGIDRLSVCLYRLGLSLTALLLLCRGAGVLGWLVPLSPSQWLTMLVVASGLCGFCLHLYDKRVRFLLQGLAWGGLMLAACGAPAILVLGAALATLCGLAFKEQFCFAIPGIRLLPLLLPLLWLLEWIRVAWAAALVALASGLLLGLLSLAKWRMPLHFDIGDRGRYQL
>NZ_CP047962.1|WP_161507670.1|4388265_4388670_+|CBS-domain-containing-protein
MLQIRDHMSRLTHSLSPQLGLAEALDRLHQADLSGLPVLDDQKRLIGFLSEQDCIPSLLTGSYHCDSRTRVEDLMSRTPLFVSPDDSILDLARQMTGAKPKIYPVREGDKVVGIINRRQVMQALNAQMKQCQAT
>NZ_CP047962.1|WP_161507669.1|4387431_4388136_-|SDR-family-oxidoreductase
MRALVTGCGRRLGFYLCEQLVAAGWQVTGSYRSERAELAHLRALGVELVQADFAVEGEVARLATALGAHDDLALIIHNASAFEPEADEPAAQLEQFEQFYRVHMAAPFQLNRALAPQLAHQHNASIIHITDIYIHAPAPQFAAYVATKAGAHSLAMSFARELAPAVRVNTIEPGPILFLDEHGDAWRQQVLARTPLAREGGLEPIWQAVTLLMANDYMTGASIRVDGGRALAVI
>NZ_CP047962.1|WP_161507668.1|4386806_4387355_+|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase
MFYLCSIGSNLDPAQHVSQAVEELLARFGQLRLSSVIQTTPVGMRSHHDFLNCLFVVQSELSAAQLKAEFVTMELAHGRDRGNPLCKVTDRPLDIDILASHERDAFAGVAVDAYLGDLLAEMYEGERVGAHKVTLRLRTSKVFAQQAFGQQPVALRQPTDERQELSAVPPDMPAHQATIRHH
>NZ_CP047962.1|WP_106885551.1|4386588_4386681_-|YnhF-family-membrane-protein
MSVEMKWALLTASGALAVILIICLASVGLA
>NZ_CP047962.1|WP_161507677.1|4396796_4397561_+|outer-membrane-protein-assembly-factor-BamD
MLLMGKKSRLLMSLALVATLITGCSSTKPKVPDEPPEVLYQKARLKLDTGNYLNAIELLEALDSRYPFGAYSSQVQLDLIYAYYKQDDTAQAIANIDRFIRLNPAHKNIDYVFYMRGLTNMAADYNFFQDFLGIDRDDKDPSYARQAFQDFKTLLQNYPNSQYAADARARMVGLKTRLARYDLGVAEYYVKRDALIAAANRAKLVVETYPDTVETEKALEIMVNAYDTLKMPTLARHAREVLAKNYPDNRIGRG
>NZ_CP047962.1|WP_161507678.1|4397760_4399089_-|CoA-disulfide-reductase
MRIVIIGGEAAGMSAAAKARRLARDAEIVVYEASEVISFGACGLPYFVGDDFQELGYMAEFTPEQFAAKGIEVKIGHRVLSLDAAAQTLRVEHKGDSFTDRYDRLMIATGAREQMPPIPGLQQQGVFGLRRMADGLALKGAVQDPRSKKAVVIGSGFIGLEVVEALVHQGKEVRLIELADRVIPEAFDSEITQHIETELREQGVSLHLGERVQALLGDGRVTGVRTDQGEYEADIVVVCTGVRPNTEFLADTGIARLGNGAIKVDRQGRSSLANVWSAGDCASVWHSVKQQQVYVPLATIANKLGRMVGENLAGAEQEFPGTLGSAALKVLGLEAGRTGLSEKEAQQLGIDYSTVVIKDKCHTNYCPGQSDIHVKLVYEAGSKRLLGGQILGRKGAVHRIDALAVAITMGVTTDQLGMLDFAYAPPFSRTWDVLNVAGNVAK
>NZ_CP047962.1|WP_161507679.1|4399161_4400562_-|L-cystine-transporter
MTLSVIGNLAILVMLLLFLYRLQQTHVSFTRRVFSGLGLGVLFGWALQLLYGVGSEVLVQTGDYLDLVGSGYVKLLQMIIIPLIMVSIIGAILKLSGGSALGKISALTIGVLIFTTMIAAGAGILMSNLFGLSAEGLTAGAAETARGAALQTSLGSVESMSLAKMVLEFIPANPFLDMTGSRKTSTIAVVIFSIFIGLSATGIARKQPEIFASFERFMQVAHAIVMRMVTLVLRLTPYGVLALMAKVVSGSNYADIINLLNFVLASYGAIAIMFLVHLLLVSLVGINPLRFLKKIMPVLAFAFTSRTSAGSIPMNVQTQTRALGIPAGIANFAASFGATIGQNGCAGIYPAMLAVMIAPTVGVNPLDPGFIMTLIAIITVSSFGVAGVGGGATFAALIVLSALDFPVALAGLLISIEPLIDMGRTALNVSGSITAGTLTSRLMGQTDMAVFNDDAEVSLDGEESAV
>NZ_CP047962.1|WP_161507680.1|4400718_4402011_-|serine-dehydratase-subunit-alpha-family-protein
MKAQWTDFITLLKREVVPALGCTEPMSVALAAANCRKLLGQVPTRISVWVSGNLFKNGMGVGVPGTGMIGLPVAAAVGITGGNPDAGLEVLKTLTPAQVDAAKALLPIIKVDVKDVPDVLYAEVLAEADGHSARVVICTDHTRIVLLEKDGEVLMEQDSAPGVQIQPAKSDKPAMTLREIVAFALEVPLTEIAFIREAASMNQALADEGLQGYGLRIGKILTEQVERKLLSDDLMTLAMRLSSAASDARMDGAMLPAMSNSGSGNQGIAATMPVVAAARFLKADDEQLARALVMSHLVAIYIKAYQNKLSALCAASTAAMGSGAAITWLLGGQFEQISHCINNMIGDVSGIICDGAGSACSMKVSTSTSAAVKSSLMAINNLHVPQSEGIVSDDVDQTIANLGRLSKQGMLDTDIEIINIMRAKQQGKAG
>NZ_CP047962.1|WP_139437938.1|4402333_4403818_-|Re/Si-specific-NAD(P)(+)-transhydrogenase-subunit-beta
MSQGLVTASYIVAAVLFILSLAGLSKQETAKHGNLFGIAGMAIALLATVFNPETSGVHWIILAMVIGGAIGVRLALKVEMTEMPELVAVLHSFVGMAAVLVGFNSFIDLHPSAPAEVVVSVGSNLDATLAAARAAFEQAASVAQVEHLSGAMLNIHLVEVFLGVFIGAVTFTGSVVAFGKLRGLISSKPLMLPHRHKLNLLAVVVSIALMIHFVNAGGSTFALLLMTLIAFAFGWHLVASIGGADMPVVVSMLNSYSGWAAAAAGFMLSNDLLIVVGALVGSSGAILSYIMCKAMNRSFISVIAGGFGSDGVASTADQEMGEYRETNAEDVADMLKNASSVIITPGYGMAVAQAQYPVAEITHKLRERGVKVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINEDFSDTDVVLVIGANDTVNPAAMEDPGSPIAGMPVLEVWKAQNVIGFKRSMNTGYAGVQNPLFFKENTQMLFGDAKASVEAILKAL
>NZ_CP047962.1|WP_161507681.1|4403829_4405356_-|Re/Si-specific-NAD(P)(+)-transhydrogenase-subunit-alpha
MQIGIPRESLAGETRVAATPATVEQLKKLGFEVAIEAGAGQLASFDDAAFEAAGASVVPSVWQADLIFKVNAPTDAEIAQIKDGATLVSFIWPAQNPELVKKLSERNINVMAMDMVPRISRAQSLDALSSMANIGGYRAVVEAAHQFGRFFTGQITAAGKVPPAKVLVIGAGVAGLAAIGTAGSLGAIVRAFDTRLEVAEQIESMGGEFLKLDFGGEDGASSDGYAKVMSDEFIKAEMELFAQQAKEVDIIITTALIPGRPAPKLITKEMVDSMKPGSVIVDLAAATGGNCEYTKPTELFVTPNGVKVIGYTDLPGRLPAQSSQLYGTNLVNLMKLMCKEKDGNVAIDFEDVVQRNMTVIQAGEVTFPPPAIAVSAAPQKPAVAKPAAKKEEAKPSNKKFVFGALGIAAFGWVAAVAPAAFLSHFTVFILACVVGYYVVWNVSHALHTPLMSVTNAISGIIVVGALLQIGQGSTLVTVLAFIAVLIASINIFGGFTVTQRMLKMFRKD
>NZ_CP047962.1|WP_161507682.1|4405861_4407025_-|alcohol-dehydrogenase
MHNFTLHTPTKVLFGKDQVAQLREQIPSDARILITYGGGSVVRSGLLAQIRHELAGMTLFEFGGIEPNPAYETLMGAVELARAERVDFLLAVGGGSVLDGTKFIAAAAHYDLAKEPWHILETVGGELASAIPLGAVLTLPATGSEMNMGAVITRRSTGDKQHFFSPFVMPRFAVLDPVLTYTLPARQVANGVVDAFIHTLEQYLTYPVNAKVQDRFAEGLLLTLIEEGPKALVEPENYDVRANIMWSATLALNGLIGAGVPQDWATHMLGHELTALHGLDHAQTLAVVLPALLDAKREQKHAKLLQYAERVWDLRSGTEEERIDGAIAATRDFFERMGVKTRLRDYGLADANIDTLLAKLEEHGMTALGEHGDIDLVQSRHIYEAAW
>NZ_CP047962.1|WP_005324436.1|4407168_4408071_+|AraC-family-transcriptional-regulator
MSNRYADLAARLARHVTTPGITPSPVEQVNLIYTTEYHGRTPVLYQPRMIVILQGHKVGYLADQVFRYDPSHYLLMTLPLPCECECFASPEQPLIGFSLEINVATLQELLLELGDALPAPAPQKSGVHSVPLSEDMFCAAERLIALMDNPLHARVLGPQTVREMLFYALHEGGGPALQALANRHNHVGQIARVLRMIESRYADNLTMEELAREVNMSVSAFHHHFKAVTATSPLQYIKSFRLHKARMMMLHDGVKAGAAAARVGYESNSQFSREYKRFFGSTPTDQASRFRDGQLRIIEG
>NZ_CP047962.1|WP_161507683.1|4408087_4408600_+|lipocalin
MRSLFCLLTALLLTACTGIADGIRPVTGFQLDRYLGTWYEIARLDHSFERGLERVSATYSRRDDGGVKVLNRGLQSDGSWREAEGKAYFVDKPDEARLKVSFFGPFYGGYNVIDLDPDYQLSLVTSYNYDYLWILSRSPNPPKEKVDALIAKAKGLGFATDRLIWVKQTP
>NZ_CP047962.1|WP_161507684.1|4410775_4411294_+|class-IV-adenylate-cyclase
MPRNIEIKARIERIDLLHPKATAIADCGPVEIAQDDTFFRCDAGRLKLRTLSPCSGELIFYRRADRQGPKESFYHLTPTSEPDRLRETLSLACGQIGRVRKMRTLFLVGRTRIHLDRVEGLGHFLELEVVLEEGEPLEAGMREAHDIMAHLGVEPSQLIEGAYLDLLLRQRA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Identity
NZ_CP047962_6	6.1\|3595865\|30\|NZ_CP047962\|CRISPRCasFinder	3595865-3595894	30	NZ_CP047963.1	40232-40261	1.0
NZ_CP047962_6	6.1\|3595865\|30\|NZ_CP047962\|CRISPRCasFinder	3595865-3595894	30	NZ_CP047962.1	1621348-1621377	1.0
NZ_CP047962_6	6.1\|3595865\|30\|NZ_CP047962\|CRISPRCasFinder	3595865-3595894	30	NZ_CP047962.1	2270945-2270974	1.0
NZ_CP047962_6	6.1\|3595865\|30\|NZ_CP047962\|CRISPRCasFinder	3595865-3595894	30	NZ_CP047962.1	2848664-2848693	1.0
NZ_CP047962_6	6.1\|3595865\|30\|NZ_CP047962\|CRISPRCasFinder	3595865-3595894	30	NZ_CP047962.1	2863947-2863976	1.0
NZ_CP047962_6	6.1\|3595865\|30\|NZ_CP047962\|CRISPRCasFinder	3595865-3595894	30	NZ_CP047962.1	2900198-2900227	1.0
NZ_CP047962_6	6.1\|3595865\|30\|NZ_CP047962\|CRISPRCasFinder	3595865-3595894	30	NZ_CP047962.1	4229931-4229960	1.0
NZ_CP047962_6	6.1\|3595865\|30\|NZ_CP047962\|CRISPRCasFinder	3595865-3595894	30	NZ_CP047962.1	792196-792225	1.0
NZ_CP047962_6	6.1\|3595865\|30\|NZ_CP047962\|CRISPRCasFinder	3595865-3595894	30	NZ_CP047962.1	2520634-2520663	1.0
NZ_CP047962_6	6.1\|3595865\|30\|NZ_CP047962\|CRISPRCasFinder	3595865-3595894	30	NZ_CP047962.1	3765841-3765870	1.0

1. spacer 6.1|3595865|30|NZ_CP047962|CRISPRCasFinder matches to position: 40232-40261, mismatch: 0, identity: 1.0

accgcctctctcctatgcaccatgggcatt	CRISPR spacer
accgcctctctcctatgcaccatgggcatt	Protospacer
******************************

2. spacer 6.1|3595865|30|NZ_CP047962|CRISPRCasFinder matches to position: 1621348-1621377, mismatch: 0, identity: 1.0

accgcctctctcctatgcaccatgggcatt	CRISPR spacer
accgcctctctcctatgcaccatgggcatt	Protospacer
******************************

3. spacer 6.1|3595865|30|NZ_CP047962|CRISPRCasFinder matches to position: 2270945-2270974, mismatch: 0, identity: 1.0

accgcctctctcctatgcaccatgggcatt	CRISPR spacer
accgcctctctcctatgcaccatgggcatt	Protospacer
******************************

4. spacer 6.1|3595865|30|NZ_CP047962|CRISPRCasFinder matches to position: 2848664-2848693, mismatch: 0, identity: 1.0

accgcctctctcctatgcaccatgggcatt	CRISPR spacer
accgcctctctcctatgcaccatgggcatt	Protospacer
******************************

5. spacer 6.1|3595865|30|NZ_CP047962|CRISPRCasFinder matches to position: 2863947-2863976, mismatch: 0, identity: 1.0

accgcctctctcctatgcaccatgggcatt	CRISPR spacer
accgcctctctcctatgcaccatgggcatt	Protospacer
******************************

6. spacer 6.1|3595865|30|NZ_CP047962|CRISPRCasFinder matches to position: 2900198-2900227, mismatch: 0, identity: 1.0

accgcctctctcctatgcaccatgggcatt	CRISPR spacer
accgcctctctcctatgcaccatgggcatt	Protospacer
******************************

7. spacer 6.1|3595865|30|NZ_CP047962|CRISPRCasFinder matches to position: 4229931-4229960, mismatch: 0, identity: 1.0

accgcctctctcctatgcaccatgggcatt	CRISPR spacer
accgcctctctcctatgcaccatgggcatt	Protospacer
******************************

8. spacer 6.1|3595865|30|NZ_CP047962|CRISPRCasFinder matches to position: 792196-792225, mismatch: 0, identity: 1.0

accgcctctctcctatgcaccatgggcatt	CRISPR spacer
accgcctctctcctatgcaccatgggcatt	Protospacer
******************************

9. spacer 6.1|3595865|30|NZ_CP047962|CRISPRCasFinder matches to position: 2520634-2520663, mismatch: 0, identity: 1.0

accgcctctctcctatgcaccatgggcatt	CRISPR spacer
accgcctctctcctatgcaccatgggcatt	Protospacer
******************************

10. spacer 6.1|3595865|30|NZ_CP047962|CRISPRCasFinder matches to position: 3765841-3765870, mismatch: 0, identity: 1.0

accgcctctctcctatgcaccatgggcatt	CRISPR spacer
accgcctctctcctatgcaccatgggcatt	Protospacer
******************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP047962_6	6.1\|3595865\|30\|NZ_CP047962\|CRISPRCasFinder	3595865-3595894	30	NZ_CP047963	Aeromonas media strain MC64 plasmid pMC64A, complete sequence	40232-40261	0	1.0
NZ_CP047962_6	6.1\|3595865\|30\|NZ_CP047962\|CRISPRCasFinder	3595865-3595894	30	NC_011409	Haemophilus influenzae plasmid ICEhin1056, complete sequence	19375-19404	1	0.967
NZ_CP047962_6	6.1\|3595865\|30\|NZ_CP047962\|CRISPRCasFinder	3595865-3595894	30	NZ_CP025964	Klebsiella pneumoniae strain WCHKP34 plasmid pIMP4_LL34, complete sequence	188156-188185	5	0.833
NZ_CP047962_6	6.1\|3595865\|30\|NZ_CP047962\|CRISPRCasFinder	3595865-3595894	30	NZ_CP038277	Raoultella ornithinolytica strain WLK218 plasmid pWLK-238550, complete sequence	137637-137666	5	0.833
NZ_CP047962_6	6.1\|3595865\|30\|NZ_CP047962\|CRISPRCasFinder	3595865-3595894	30	NZ_CP038277	Raoultella ornithinolytica strain WLK218 plasmid pWLK-238550, complete sequence	135313-135342	5	0.833
NZ_CP047962_6	6.1\|3595865\|30\|NZ_CP047962\|CRISPRCasFinder	3595865-3595894	30	NZ_CP038280	Raoultella ornithinolytica strain WLK218 plasmid pWLK-NDM, complete sequence	65816-65845	5	0.833
NZ_CP047962_6	6.1\|3595865\|30\|NZ_CP047962\|CRISPRCasFinder	3595865-3595894	30	NZ_CP038280	Raoultella ornithinolytica strain WLK218 plasmid pWLK-NDM, complete sequence	8277-8306	5	0.833
NZ_CP047962_6	6.1\|3595865\|30\|NZ_CP047962\|CRISPRCasFinder	3595865-3595894	30	NZ_MH011352	Klebsiella pneumoniae strain 185 plasmid pNDM-185, complete sequence	122022-122051	5	0.833
NZ_CP047962_6	6.1\|3595865\|30\|NZ_CP047962\|CRISPRCasFinder	3595865-3595894	30	NZ_MH011352	Klebsiella pneumoniae strain 185 plasmid pNDM-185, complete sequence	45410-45439	5	0.833
NZ_CP047962_6	6.1\|3595865\|30\|NZ_CP047962\|CRISPRCasFinder	3595865-3595894	30	NZ_CP028567	Aeromonas hydrophila subsp. hydrophila strain WCHAH045096 plasmid pMCR5_045096, complete sequence	229112-229141	5	0.833
NZ_CP047962_6	6.1\|3595865\|30\|NZ_CP047962\|CRISPRCasFinder	3595865-3595894	30	NZ_CP028567	Aeromonas hydrophila subsp. hydrophila strain WCHAH045096 plasmid pMCR5_045096, complete sequence	234528-234557	5	0.833
NZ_CP047962_6	6.1\|3595865\|30\|NZ_CP047962\|CRISPRCasFinder	3595865-3595894	30	NZ_CP038276	Raoultella ornithinolytica strain WLK218 plasmid pWLK-107717, complete sequence	23-52	5	0.833
NZ_CP047962_6	6.1\|3595865\|30\|NZ_CP047962\|CRISPRCasFinder	3595865-3595894	30	NZ_MH475146	Citrobacter freundii strain 164 plasmid pCf164_LMB-1, complete sequence	132997-133026	5	0.833
NZ_CP047962_6	6.1\|3595865\|30\|NZ_CP047962\|CRISPRCasFinder	3595865-3595894	30	NZ_CP049047	Enterobacter hormaechei strain Y233 plasmid pIHI2-233, complete sequence	191358-191387	5	0.833

1. spacer 6.1|3595865|30|NZ_CP047962|CRISPRCasFinder matches to NZ_CP047963 (Aeromonas media strain MC64 plasmid pMC64A, complete sequence) position: , mismatch: 0, identity: 1.0

accgcctctctcctatgcaccatgggcatt	CRISPR spacer
accgcctctctcctatgcaccatgggcatt	Protospacer
******************************

2. spacer 6.1|3595865|30|NZ_CP047962|CRISPRCasFinder matches to NC_011409 (Haemophilus influenzae plasmid ICEhin1056, complete sequence) position: , mismatch: 1, identity: 0.967

accgcctctctcctatgcaccatgggcatt	CRISPR spacer
accgcctctctcctatgcaccaggggcatt	Protospacer
********************** *******

3. spacer 6.1|3595865|30|NZ_CP047962|CRISPRCasFinder matches to NZ_CP025964 (Klebsiella pneumoniae strain WCHKP34 plasmid pIMP4_LL34, complete sequence) position: , mismatch: 5, identity: 0.833

accgcctctctcctatgcaccatgggcatt	CRISPR spacer
gcctcttctctcctatgcaccatgggtgtt	Protospacer
.** *.********************..**

4. spacer 6.1|3595865|30|NZ_CP047962|CRISPRCasFinder matches to NZ_CP038277 (Raoultella ornithinolytica strain WLK218 plasmid pWLK-238550, complete sequence) position: , mismatch: 5, identity: 0.833

accgcctctctcctatgcaccatgggcatt	CRISPR spacer
gcctcttctctcctatgcaccatgggtgtt	Protospacer
.** *.********************..**

5. spacer 6.1|3595865|30|NZ_CP047962|CRISPRCasFinder matches to NZ_CP038277 (Raoultella ornithinolytica strain WLK218 plasmid pWLK-238550, complete sequence) position: , mismatch: 5, identity: 0.833

accgcctctctcctatgcaccatgggcatt	CRISPR spacer
gcctcttctctcctatgcaccatgggtgtt	Protospacer
.** *.********************..**

6. spacer 6.1|3595865|30|NZ_CP047962|CRISPRCasFinder matches to NZ_CP038280 (Raoultella ornithinolytica strain WLK218 plasmid pWLK-NDM, complete sequence) position: , mismatch: 5, identity: 0.833

accgcctctctcctatgcaccatgggcatt	CRISPR spacer
gcctcttctctcctatgcaccatgggtgtt	Protospacer
.** *.********************..**

7. spacer 6.1|3595865|30|NZ_CP047962|CRISPRCasFinder matches to NZ_CP038280 (Raoultella ornithinolytica strain WLK218 plasmid pWLK-NDM, complete sequence) position: , mismatch: 5, identity: 0.833

accgcctctctcctatgcaccatgggcatt	CRISPR spacer
gcctcttctctcctatgcaccatgggtgtt	Protospacer
.** *.********************..**

8. spacer 6.1|3595865|30|NZ_CP047962|CRISPRCasFinder matches to NZ_MH011352 (Klebsiella pneumoniae strain 185 plasmid pNDM-185, complete sequence) position: , mismatch: 5, identity: 0.833

accgcctctctcctatgcaccatgggcatt	CRISPR spacer
gcctcttctctcctatgcaccatgggtgtt	Protospacer
.** *.********************..**

9. spacer 6.1|3595865|30|NZ_CP047962|CRISPRCasFinder matches to NZ_MH011352 (Klebsiella pneumoniae strain 185 plasmid pNDM-185, complete sequence) position: , mismatch: 5, identity: 0.833

accgcctctctcctatgcaccatgggcatt	CRISPR spacer
gcctcttctctcctatgcaccatgggtgtt	Protospacer
.** *.********************..**

10. spacer 6.1|3595865|30|NZ_CP047962|CRISPRCasFinder matches to NZ_CP028567 (Aeromonas hydrophila subsp. hydrophila strain WCHAH045096 plasmid pMCR5_045096, complete sequence) position: , mismatch: 5, identity: 0.833

accgcctctctcctatgcaccatgggcatt	CRISPR spacer
gcctcttctctcctatgcaccatgggtgtt	Protospacer
.** *.********************..**

11. spacer 6.1|3595865|30|NZ_CP047962|CRISPRCasFinder matches to NZ_CP028567 (Aeromonas hydrophila subsp. hydrophila strain WCHAH045096 plasmid pMCR5_045096, complete sequence) position: , mismatch: 5, identity: 0.833

accgcctctctcctatgcaccatgggcatt	CRISPR spacer
gcctcttctctcctatgcaccatgggtgtt	Protospacer
.** *.********************..**

12. spacer 6.1|3595865|30|NZ_CP047962|CRISPRCasFinder matches to NZ_CP038276 (Raoultella ornithinolytica strain WLK218 plasmid pWLK-107717, complete sequence) position: , mismatch: 5, identity: 0.833

accgcctctctcctatgcaccatgggcatt	CRISPR spacer
gcctcttctctcctatgcaccatgggtgtt	Protospacer
.** *.********************..**

13. spacer 6.1|3595865|30|NZ_CP047962|CRISPRCasFinder matches to NZ_MH475146 (Citrobacter freundii strain 164 plasmid pCf164_LMB-1, complete sequence) position: , mismatch: 5, identity: 0.833

accgcctctctcctatgcaccatgggcatt	CRISPR spacer
gcctcttctctcctatgcaccatgggtgtt	Protospacer
.** *.********************..**

14. spacer 6.1|3595865|30|NZ_CP047962|CRISPRCasFinder matches to NZ_CP049047 (Enterobacter hormaechei strain Y233 plasmid pIHI2-233, complete sequence) position: , mismatch: 5, identity: 0.833

accgcctctctcctatgcaccatgggcatt	CRISPR spacer
gcctcttctctcctatgcaccatgggtgtt	Protospacer
.** *.********************..**

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

37931 : 109401

Bacillus_phage(14.29%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_161506701.1\|37931_38678_-\|tRNA	tRNA (guanosine(18)-2'-O)-methyltransferase TrmH	NA	NA	NA	NA
WP_161506702.1\|38836_40954_-	bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase	A0A291L9W9	Bordetella_phage	3.0e-12	36.4
WP_005307060.1\|41089_41365_-	DNA-directed RNA polymerase subunit omega	NA	NA	NA	NA
WP_139745085.1\|41444_42071_-	guanylate kinase	K4JYM5	Abalone_herpesvirus	3.2e-23	36.3
WP_161506703.1\|42371_43427_-	glycosyltransferase family 9 protein	NA	NA	NA	NA
WP_161507810.1\|43567_44281_+	3-deoxy-D-manno-octulosonic acid kinase	NA	NA	NA	NA
WP_161506704.1\|44613_45477_+	sensor domain-containing diguanylate cyclase	NA	NA	NA	NA
WP_161506705.1\|45548_46418_-	DMT family transporter	NA	NA	NA	NA
WP_161507811.1\|46460_46937_+	hypothetical protein	NA	NA	NA	NA
WP_139437058.1\|47188_48088_-	EamA family transporter	NA	NA	NA	NA
WP_161506706.1\|48178_49138_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_161506707.1\|49116_50130_-\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_025325220.1\|50322_50757_-	universal stress protein	NA	NA	NA	NA
WP_161506708.1\|51135_52323_+	trans-2-enoyl-CoA reductase family protein	NA	NA	NA	NA
WP_161507812.1\|52466_54023_-	GGDEF domain-containing protein	A0A127AWB9	Bacillus_phage	6.0e-18	38.2
WP_005326403.1\|54232_54757_+	non-heme ferritin	NA	NA	NA	NA
WP_161507813.1\|54918_56103_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_161506709.1\|56289_57510_-	MFS transporter	NA	NA	NA	NA
WP_005326407.1\|57732_58371_+	leucine efflux protein LeuE	NA	NA	NA	NA
WP_161506710.1\|58413_59100_-	fimbria/pilus periplasmic chaperone	NA	NA	NA	NA
WP_099369027.1\|59479_60496_+\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	4.9e-186	99.1
WP_084865641.1\|62905_64108_-\|transposase	ISL3-like element ISAeme19 family transposase	A9YX10	Burkholderia_phage	1.4e-102	53.2
WP_161506711.1\|64099_64534_+	Hpt domain-containing protein	NA	NA	NA	NA
WP_161506712.1\|64572_65013_-	hypothetical protein	NA	NA	NA	NA
WP_161506713.1\|65186_66860_+	sensor histidine kinase	NA	NA	NA	NA
WP_161506714.1\|66989_67721_+	response regulator transcription factor	NA	NA	NA	NA
WP_042650638.1\|67830_69027_+	MFS transporter	NA	NA	NA	NA
WP_161506715.1\|69098_70223_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_161506716.1\|70219_70729_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	3.3e-18	40.0
WP_161506717.1\|71169_73005_+	TonB-dependent receptor	A0A0P0I887	Acinetobacter_phage	4.6e-09	30.2
WP_161506718.1\|73120_73909_+	glutamate racemase	NA	NA	NA	NA
WP_005326417.1\|73913_74405_-	RNA-binding protein	NA	NA	NA	NA
WP_161506719.1\|80568_81405_+\|tRNA	tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA	S4VW33	Pandoravirus	1.0e-16	35.0
WP_161506720.1\|81426_81861_-	SufE family protein	NA	NA	NA	NA
WP_161506721.1\|81874_83095_-	cysteine desulfurase	Q2XUY6	environmental_halophage	8.7e-97	44.1
WP_161506722.1\|83247_85260_+	DNA helicase Rep	A7KV33	Bacillus_phage	9.8e-122	39.4
WP_161506723.1\|85246_87547_-	EAL domain-containing protein	G3MA91	Bacillus_virus	5.4e-23	34.6
WP_161506724.1\|87631_88084_-	cytochrome c5 family protein	NA	NA	NA	NA
WP_161506725.1\|88358_89384_-	L-threonine 3-dehydrogenase	R9TPW0	Vibrio_phage	4.7e-19	82.7
WP_081805940.1\|89473_90664_-	glycine C-acetyltransferase	V5LQ39	Emiliania_huxleyi_virus	2.4e-35	27.2
WP_041206718.1\|90848_91493_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_005327364.1\|91639_92599_+	ADP-glyceromanno-heptose 6-epimerase	A0A2K9L0I7	Tupanvirus	7.0e-17	26.6
WP_148304719.1\|92603_93710_+	glycosyltransferase	NA	NA	NA	NA
WP_161506726.1\|93732_94989_+	O-antigen ligase family protein	NA	NA	NA	NA
WP_161507814.1\|95161_96433_-\|transposase	transposase	NA	NA	NA	NA
WP_041205384.1\|97819_98917_+\|transposase	ISAs1-like element ISAeme2 family transposase	NA	NA	NA	NA
WP_161506727.1\|99835_100258_+	hypothetical protein	NA	NA	NA	NA
WP_004576012.1\|100335_101754_+\|transposase	IS66-like element ISAs21 family transposase	NA	NA	NA	NA
WP_081805941.1\|102004_104002_+	LTA synthase family protein	NA	NA	NA	NA
WP_161506728.1\|104033_105014_+	oxidoreductase	NA	NA	NA	NA
WP_005331099.1\|105394_105733_+	DUF2799 domain-containing protein	NA	NA	NA	NA
WP_005331102.1\|106025_106460_-	flagellar basal body-associated protein FliL	NA	NA	NA	NA
WP_041206721.1\|106605_107157_+	chorismate lyase	NA	NA	NA	NA
WP_005331104.1\|107153_108017_+	4-hydroxybenzoate octaprenyltransferase	NA	NA	NA	NA
WP_041205828.1\|108063_109401_-\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA

DBSCAN-SWA_2

363685 : 415873

Staphylococcus_prophage(16.67%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_019706001.1\|363685_364633_-\|transposase	IS30-like element ISAs2 family transposase	Q9MBM9	Staphylococcus_prophage	1.4e-41	35.7
WP_041206499.1\|364758_365964_+	nucleoside permease	NA	NA	NA	NA
WP_161506851.1\|366357_366918_-	cytochrome B	NA	NA	NA	NA
WP_005332935.1\|366966_367236_-	PepSY domain-containing protein	NA	NA	NA	NA
WP_005332933.1\|367353_367806_-	YaiI/YqxD family protein	NA	NA	NA	NA
WP_161507817.1\|367946_368912_+	zinc transporter ZntB	NA	NA	NA	NA
WP_042649397.1\|368921_369440_+	mechanosensitive ion channel	NA	NA	NA	NA
WP_042649398.1\|369479_369728_-	hypothetical protein	NA	NA	NA	NA
WP_161506852.1\|369817_371605_-	sodium:proton antiporter	NA	NA	NA	NA
WP_005332927.1\|371737_372259_-	MltR family transcriptional regulator	NA	NA	NA	NA
WP_042649400.1\|372375_373521_-	mannitol-1-phosphate 5-dehydrogenase	NA	NA	NA	NA
WP_041206491.1\|373558_375487_-	PTS mannitol transporter subunit IICBA	NA	NA	NA	NA
WP_161506853.1\|376341_378357_-	exoribonuclease II	Q0GXV6	Lactococcus_phage	1.4e-30	29.0
WP_161506854.1\|378457_379357_-	LysR family transcriptional regulator ArgP	NA	NA	NA	NA
WP_161506855.1\|379596_380223_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_161506856.1\|380287_381070_+	LuxR family transcriptional regulator	A0A1I9KF49	Aeromonas_phage	1.1e-55	48.2
WP_161506857.1\|381332_381953_+	amino acid transporter	NA	NA	NA	NA
WP_043132565.1\|382080_384060_+	bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase	NA	NA	NA	NA
WP_161506858.1\|384194_385118_-	LpxL/LpxP family Kdo(2)-lipid IV(A) lauroyl/palmitoleoyl acyltransferase	A0A1W6JP29	Morganella_phage	3.3e-56	40.5
WP_139751753.1\|385371_386799_+	bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE	A0A0K0KVL9	Prochlorococcus_phage	2.7e-17	38.4
WP_042649405.1\|386898_388224_-	outer membrane channel protein TolC	NA	NA	NA	NA
WP_025325572.1\|388529_389171_+	ADP-ribose diphosphatase	A0A1S6L1P8	Vibrio_phage	1.1e-23	35.6
WP_041206485.1\|389222_389669_+	DUF1249 domain-containing protein	NA	NA	NA	NA
WP_161506859.1\|389697_390516_+	3',5'-cyclic-AMP phosphodiesterase	NA	NA	NA	NA
WP_161506860.1\|390529_391117_+	esterase YqiA	NA	NA	NA	NA
WP_161506861.1\|391119_391743_+	NUDIX hydrolase	NA	NA	NA	NA
WP_161506862.1\|391781_392177_+	GFA family protein	NA	NA	NA	NA
WP_161506863.1\|392316_394212_+	DNA topoisomerase IV subunit B	G3M9Z3	Bacillus_virus	4.5e-92	36.3
WP_161506864.1\|394290_396582_+	DNA topoisomerase IV subunit A	G3M9Z5	Bacillus_virus	9.6e-89	36.5
WP_161506865.1\|396635_396809_-	SH3 domain-containing protein	NA	NA	NA	NA
WP_019706001.1\|396866_397814_-\|transposase	IS30-like element ISAs2 family transposase	Q9MBM9	Staphylococcus_prophage	1.4e-41	35.7
WP_161506866.1\|398033_399041_+\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	2.2e-183	99.1
WP_102948393.1\|399069_400274_-\|transposase	IS3 family transposase	Q9ZXG3	Shigella_phage	4.5e-114	70.1
WP_106885079.1\|402067_402280_+	hypothetical protein	NA	NA	NA	NA
WP_161506867.1\|402394_403192_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_161506868.1\|403571_403982_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_161506869.1\|404051_404426_-	hypothetical protein	NA	NA	NA	NA
WP_161507818.1\|404497_404749_-	hypothetical protein	NA	NA	NA	NA
WP_025325588.1\|404945_405161_-	glycine zipper 2TM domain-containing protein	NA	NA	NA	NA
WP_161506870.1\|405500_406403_-	hypothetical protein	NA	NA	NA	NA
WP_161506871.1\|406413_407175_-	hypothetical protein	NA	NA	NA	NA
WP_161506872.1\|407188_407719_-	hypothetical protein	NA	NA	NA	NA
WP_025325592.1\|407726_408011_-	DnaJ domain-containing protein	A0A1V0SDD4	Indivirus	7.3e-07	40.0
WP_042649992.1\|408372_408792_+	EF-hand domain-containing protein	NA	NA	NA	NA
WP_161506873.1\|408877_409405_-	protein disulfide oxidoreductase	NA	NA	NA	NA
WP_161506874.1\|409408_410140_-	thioredoxin domain-containing protein	NA	NA	NA	NA
WP_161506875.1\|410136_412179_-	protein-disulfide reductase	NA	NA	NA	NA
WP_139751114.1\|412229_412607_-	hypothetical protein	NA	NA	NA	NA
WP_139438739.1\|412783_413512_+	1-acylglycerol-3-phosphate O-acyltransferase	NA	NA	NA	NA
WP_161506876.1\|413719_414382_+	phage shock protein PspA	NA	NA	NA	NA
WP_161506877.1\|414384_414591_+	PspC domain-containing protein	NA	NA	NA	NA
WP_005331057.1\|414640_414859_+	envelope stress response protein PspG	NA	NA	NA	NA
WP_161506878.1\|414907_415873_-\|transposase	IS1595 family transposase	NA	NA	NA	NA

DBSCAN-SWA_3

748027 : 870414

Vibrio_phage(13.64%)

tRNA,integrase,protease,transposase

attL 806920:806979|attR 855686:856684

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_024945937.1\|748027_749590_+\|transposase	IS21 family transposase	K4I413	Acidithiobacillus_phage	6.2e-124	46.2
WP_024945936.1\|749615_750371_+	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	6.9e-52	45.4
WP_005323871.1\|750562_752710_+	adenosylcobalamin-dependent ribonucleoside-diphosphate reductase	F9VHP7	Thermus_phage	1.7e-143	41.8
WP_005323870.1\|752719_753403_+	hypothetical protein	A0A191VYJ2	Roseobacter_phage	3.1e-35	40.6
WP_041206373.1\|753844_755215_+	PhoH family protein	A0A2I7SAD7	Vibrio_phage	1.6e-107	45.5
WP_005323866.1\|755284_755989_-	thiamine ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.9e-25	38.9
WP_041206372.1\|756067_757675_-	thiamine/thiamine pyrophosphate ABC transporter, permease protein	NA	NA	NA	NA
WP_005323861.1\|757671_758652_-	thiamine ABC transporter substrate binding subunit	NA	NA	NA	NA
WP_005323856.1\|758933_759224_+	PilZ domain-containing protein	NA	NA	NA	NA
WP_005323854.1\|759328_760255_-	hypothetical protein	NA	NA	NA	NA
WP_005323852.1\|760367_760967_-	3-isopropylmalate dehydratase small subunit	NA	NA	NA	NA
WP_005323850.1\|760979_762377_-	3-isopropylmalate dehydratase large subunit	NA	NA	NA	NA
WP_005323847.1\|762409_763495_-	3-isopropylmalate dehydrogenase	NA	NA	NA	NA
WP_005323845.1\|763693_765256_-	2-isopropylmalate synthase	NA	NA	NA	NA
WP_005323843.1\|765662_766286_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_005323841.1\|766426_766930_+	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_005323839.1\|766926_768036_+	glycosyl transferase	NA	NA	NA	NA
WP_005323836.1\|768613_770332_+	acetolactate synthase 3 large subunit	G9E4W7	Ostreococcus_lucimarinus_virus	3.0e-18	28.1
WP_025328160.1\|770331_770826_+	acetolactate synthase small subunit	NA	NA	NA	NA
WP_041206371.1\|771225_773379_-	phosphate acetyltransferase	NA	NA	NA	NA
WP_005323830.1\|773448_774651_-	acetate kinase	NA	NA	NA	NA
WP_025328157.1\|774953_775394_+	DUF412 domain-containing protein	NA	NA	NA	NA
WP_005323826.1\|775439_775940_-	YfbU family protein	NA	NA	NA	NA
WP_005323824.1\|776159_776624_-	thioredoxin-dependent thiol peroxidase	NA	NA	NA	NA
WP_025328154.1\|776647_777181_-	hypothetical protein	NA	NA	NA	NA
WP_041206370.1\|777380_778268_+	4-hydroxy-tetrahydrodipicolinate synthase	NA	NA	NA	NA
WP_041206367.1\|778290_779385_+	outer membrane protein assembly factor BamC	NA	NA	NA	NA
WP_041206365.1\|779554_780658_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	NA	NA	NA	NA
WP_005323815.1\|780785_781388_-	short chain dehydrogenase	NA	NA	NA	NA
WP_005323813.1\|781486_782386_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_005323812.1\|782463_783078_+	DUF2057 domain-containing protein	NA	NA	NA	NA
WP_041206363.1\|783148_783595_+	HIT domain-containing protein	NA	NA	NA	NA
WP_005323808.1\|783713_784409_+	DUF3334 family protein	NA	NA	NA	NA
WP_005323806.1\|784477_785476_-	DUF2860 domain-containing protein	NA	NA	NA	NA
WP_005323804.1\|785678_787991_+	aerobic respiration two-component sensor histidine kinase ArcB	A0A1V0SGX0	Hokovirus	8.3e-40	30.3
WP_041206361.1\|788024_789395_+	dGTPase	NA	NA	NA	NA
WP_005328210.1\|789687_789891_+	hypothetical protein	NA	NA	NA	NA
WP_021141311.1\|790720_791857_+\|transposase	ISAs1-like element ISAs12 family transposase	NA	NA	NA	NA
WP_012564931.1\|792278_793226_+\|transposase	IS30-like element ISAeca1 family transposase	Q9MBM9	Staphylococcus_prophage	1.0e-44	36.9
WP_148304712.1\|793348_794014_+	EAL domain-containing protein	NA	NA	NA	NA
WP_041205088.1\|798717_799080_-	DUF2061 domain-containing protein	NA	NA	NA	NA
WP_005325909.1\|799261_799468_+	hypothetical protein	NA	NA	NA	NA
WP_161506893.1\|799549_800404_-	23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ	NA	NA	NA	NA
WP_005325916.1\|800397_800859_-	DUF2390 domain-containing protein	NA	NA	NA	NA
WP_005325918.1\|800851_802762_-	ABC transporter ATP-binding protein	A0A2K9L0W2	Tupanvirus	2.1e-73	32.8
WP_005325920.1\|802914_803325_+	CBS domain-containing protein	NA	NA	NA	NA
WP_001809438.1\|803673_804705_+\|transposase	IS630-like element ISAhy2 family transposase	NA	NA	NA	NA
WP_011191341.1\|804951_806226_-\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA
WP_161506894.1\|806901_807882_-\|transposase	IS5 family transposase	Q38213	Escherichia_phage	9.8e-176	99.4
806920:806979	attL	NA	NA	NA	NA
WP_041205091.1\|807993_809061_+	porin	Q1MVN1	Enterobacteria_phage	6.3e-43	33.7
WP_041204923.1\|809556_810699_+\|transposase	IS4-like element ISAs18 family transposase	NA	NA	NA	NA
WP_041205093.1\|811726_812335_-	arylesterase	NA	NA	NA	NA
WP_005325231.1\|812392_813103_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.9e-32	37.9
WP_005325230.1\|813099_815541_+	FtsX-like permease family protein	NA	NA	NA	NA
WP_005325229.1\|815605_816511_-	TIGR01777 family protein	NA	NA	NA	NA
WP_041205096.1\|816772_818323_+	EAL domain-containing protein	NA	NA	NA	NA
WP_005325227.1\|818450_819632_-	PLP-dependent aminotransferase family protein	NA	NA	NA	NA
WP_005325226.1\|819833_820901_-	M20/M25/M40 family metallo-hydrolase	NA	NA	NA	NA
WP_041205099.1\|821178_821892_+\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_005325222.1\|821935_822268_+	YggL family protein	NA	NA	NA	NA
WP_005325214.1\|822367_823288_+	glutaminase B	NA	NA	NA	NA
WP_041205101.1\|823317_824610_+	sulfurtransferase	NA	NA	NA	NA
WP_041205103.1\|825032_825242_+	YgdI/YgdR family lipoprotein	NA	NA	NA	NA
WP_005325210.1\|825285_828849_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	2.0e-16	36.8
WP_005325209.1\|828948_830226_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_080675078.1\|830698_830920_+	hypothetical protein	NA	NA	NA	NA
WP_005342491.1\|831679_832630_-\|transposase	IS1595-like element ISKpn3 family transposase	NA	NA	NA	NA
WP_161506895.1\|832903_834085_+\|integrase	site-specific integrase	A0A0M3LRG1	Mannheimia_phage	1.1e-08	26.4
WP_161506896.1\|834094_836299_+	DUF927 domain-containing protein	NA	NA	NA	NA
WP_161506897.1\|837020_838262_-\|integrase	tyrosine-type recombinase/integrase	A0A221SAN4	Ralstonia_phage	2.3e-28	31.1
WP_081934480.1\|838757_839177_-	DUF2787 domain-containing protein	NA	NA	NA	NA
WP_161506898.1\|839188_839392_-	hypothetical protein	NA	NA	NA	NA
WP_161506899.1\|839402_839807_-	hypothetical protein	NA	NA	NA	NA
WP_161506900.1\|839829_840132_-	DUF1232 domain-containing protein	A0A2I7S9Z5	Vibrio_phage	2.7e-07	39.2
WP_161506901.1\|840128_840689_-	hypothetical protein	NA	NA	NA	NA
WP_161506902.1\|841005_841380_+	hypothetical protein	NA	NA	NA	NA
WP_161506903.1\|841481_842744_-	site-specific DNA-methyltransferase	Q1MVP0	Enterobacteria_phage	1.1e-59	34.3
WP_161506904.1\|842826_843243_-	hypothetical protein	NA	NA	NA	NA
WP_041204928.1\|843218_844346_-\|transposase	ISAs1-like element ISKpn9 family transposase	NA	NA	NA	NA
WP_161507814.1\|844927_846199_+\|transposase	transposase	NA	NA	NA	NA
WP_011191341.1\|847240_848515_-\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA
WP_064162514.1\|849839_850322_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_161506905.1\|850269_850893_+\|transposase	IS630 family transposase	M4M9P8	Vibrio_phage	6.8e-13	63.5
WP_042012893.1\|850873_851182_+	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_042012890.1\|851181_851547_+	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_052814785.1\|851596_853207_+\|transposase	IS66 family transposase	A0A218MNE7	uncultured_virus	2.5e-43	32.8
WP_099993964.1\|855631_856648_-\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	2.2e-186	99.4
WP_139750635.1\|856814_857747_-	hypothetical protein	NA	NA	NA	NA
855686:856684	attR	NA	NA	NA	NA
WP_041205105.1\|857810_858905_-	cellulase family glycosylhydrolase	NA	NA	NA	NA
WP_005326773.1\|859209_860250_+	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_081805630.1\|860399_860735_-	hypothetical protein	NA	NA	NA	NA
WP_041205107.1\|860831_861803_-	galactose mutarotase	NA	NA	NA	NA
WP_161506906.1\|861799_862951_-	galactokinase	NA	NA	NA	NA
WP_139750636.1\|862947_863994_-	UDP-glucose--hexose-1-phosphate uridylyltransferase	NA	NA	NA	NA
WP_041205112.1\|864045_865059_-	UDP-glucose 4-epimerase GalE	A0A2K9L1R4	Tupanvirus	1.0e-82	46.8
WP_041205116.1\|865940_868217_-\|protease	M6 family metalloprotease domain-containing protein	NA	NA	NA	NA
WP_041206820.1\|868649_868985_+	ribonuclease E inhibitor RraB	NA	NA	NA	NA
WP_041205253.1\|869076_870414_-\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA

DBSCAN-SWA_4

883170 : 937809

Streptococcus_phage(25.0%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005327088.1\|883170_884586_+\|tRNA	glutamate--tRNA ligase	NA	NA	NA	NA
WP_005327087.1\|884588_884729_+	hypothetical protein	NA	NA	NA	NA
WP_005323562.1\|887729_888647_+\|transposase	IS5 family transposase	A0A1V0E8E1	Vibrio_phage	2.6e-101	59.5
WP_005327079.1\|890517_891753_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_161506907.1\|891764_892400_-	energy transducer TonB	NA	NA	NA	NA
WP_005327075.1\|892416_892824_-	biopolymer transporter ExbD	NA	NA	NA	NA
WP_005327072.1\|892890_893418_-	MotA/TolQ/ExbB proton channel family protein	NA	NA	NA	NA
WP_005327070.1\|893428_894802_-	MotA/TolQ/ExbB proton channel family protein	NA	NA	NA	NA
WP_005327067.1\|894798_895563_-	DUF3450 domain-containing protein	NA	NA	NA	NA
WP_041205127.1\|895666_898273_-	TonB-dependent receptor	A0A0P0I887	Acinetobacter_phage	2.2e-36	26.1
WP_021141311.1\|898814_899951_+\|transposase	ISAs1-like element ISAs12 family transposase	NA	NA	NA	NA
WP_019706001.1\|900109_901057_+\|transposase	IS30-like element ISAs2 family transposase	Q9MBM9	Staphylococcus_prophage	1.4e-41	35.7
WP_041205130.1\|901549_902575_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_005325957.1\|902577_903621_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_005325959.1\|903703_905521_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_041206825.1\|905534_906593_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	5.7e-12	24.3
WP_041205133.1\|906687_907689_+	dipeptide ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.4e-20	30.0
WP_041205135.1\|908298_909750_-	aminoacyl-histidine dipeptidase	NA	NA	NA	NA
WP_005325980.1\|910688_911156_+	xanthine phosphoribosyltransferase	NA	NA	NA	NA
WP_005325987.1\|911328_912597_+	esterase FrsA	NA	NA	NA	NA
WP_041205137.1\|912659_913052_+	sigma factor-binding protein Crl	NA	NA	NA	NA
WP_005325991.1\|913185_914289_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	2.6e-60	41.5
WP_041205139.1\|914413_915667_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	9.2e-94	45.5
WP_041205140.1\|915817_916450_+	murein L,D-transpeptidase catalytic domain family protein	NA	NA	NA	NA
WP_005325997.1\|916523_916955_-	universal stress protein	NA	NA	NA	NA
WP_041205143.1\|917157_917910_+	hypothetical protein	NA	NA	NA	NA
WP_005325999.1\|917990_918494_-	RNA methyltransferase	NA	NA	NA	NA
WP_161506908.1\|918812_921437_+	molybdopterin-dependent oxidoreductase	NA	NA	NA	NA
WP_081805634.1\|921466_922225_+	uroporphyrinogen-III C-methyltransferase	NA	NA	NA	NA
WP_041205148.1\|922350_922932_+	ANTAR domain-containing protein	NA	NA	NA	NA
WP_005326004.1\|923247_924579_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_049832146.1\|924593_925553_+	ABC transporter permease	NA	NA	NA	NA
WP_005326006.1\|925584_926406_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	7.3e-31	38.5
WP_005326007.1\|926432_929006_+	nitrite reductase large subunit	NA	NA	NA	NA
WP_005326008.1\|929053_929413_+	nitrite reductase small subunit NirD	NA	NA	NA	NA
WP_005326010.1\|929558_930650_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_005326011.1\|930643_931552_+	pseudouridine-5'-phosphate glycosidase	NA	NA	NA	NA
WP_041205152.1\|931624_932326_-	carbonic anhydrase family protein	NA	NA	NA	NA
WP_011191341.1\|933233_934508_-\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA
WP_021141311.1\|934971_936108_+\|transposase	ISAs1-like element ISAs12 family transposase	NA	NA	NA	NA
WP_011191341.1\|936534_937809_+\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA

DBSCAN-SWA_5

1323741 : 1331433

Enterobacteria_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010675337.1\|1323741_1324416_-	response regulator	W8CYM9	Bacillus_phage	1.8e-27	33.3
WP_161506951.1\|1325378_1326464_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	2.2e-96	51.6
WP_161506952.1\|1326463_1327351_+	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	1.8e-27	34.8
WP_161506953.1\|1327463_1328339_+	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	6.6e-107	64.1
WP_161506954.1\|1328446_1328998_+	dTDP-4-dehydrorhamnose 3,5-epimerase	A0A291LA62	Escherichia_phage	5.9e-53	58.0
WP_161506955.1\|1328999_1330244_+	oligosaccharide flippase family protein	NA	NA	NA	NA
WP_161506956.1\|1330308_1331433_+	UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)	A0A1V0SAG5	Catovirus	6.0e-28	29.7

DBSCAN-SWA_6

1377373 : 1449326

Salmonella_phage(16.67%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005328710.1\|1377373_1378480_-\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_005328711.1\|1378637_1379105_-	NUDIX hydrolase	A0A023W5N2	Serratia_phage	8.6e-05	62.2
WP_041205353.1\|1379101_1380034_-	pseudouridine synthase	NA	NA	NA	NA
WP_005328714.1\|1380169_1380937_-	PTS transporter subunit EIIA	NA	NA	NA	NA
WP_005328715.1\|1380937_1381243_-	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_005328717.1\|1381455_1382862_-	hexose-6-phosphate:phosphate antiporter	NA	NA	NA	NA
WP_005328732.1\|1383325_1385230_-	PTS transporter subunit EIIA	NA	NA	NA	NA
WP_011191341.1\|1385841_1387116_-\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA
WP_161506965.1\|1387180_1387498_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_041206859.1\|1388210_1388465_-	hypothetical protein	NA	NA	NA	NA
WP_043132489.1\|1388669_1389113_-	copper resistance protein CopD	NA	NA	NA	NA
WP_041205355.1\|1390132_1392457_+	hypothetical protein	J9Q6D6	Salmonella_phage	5.1e-05	27.6
WP_005328918.1\|1392654_1394541_-	PTS fructose transporter subunit EIIC	NA	NA	NA	NA
WP_005328921.1\|1395504_1396053_-	YgjV family protein	NA	NA	NA	NA
WP_005328923.1\|1396241_1397441_-	mannose-6-phosphate isomerase, class I	NA	NA	NA	NA
WP_041205357.1\|1397570_1398446_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_005328927.1\|1398641_1399895_+	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	1.6e-13	72.2
WP_005332623.1\|1400496_1401828_-	D-serine ammonia-lyase	NA	NA	NA	NA
WP_005332620.1\|1401845_1403183_-	D-serine transporter DsdX	NA	NA	NA	NA
WP_005332617.1\|1403413_1404358_+	DNA-binding transcriptional regulator DsdC	NA	NA	NA	NA
WP_005332615.1\|1404766_1405174_+	H-NS histone family protein	NA	NA	NA	NA
WP_011191341.1\|1405340_1406615_-\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA
WP_041205359.1\|1407048_1408155_-	3-deoxy-7-phosphoheptulonate synthase	A0A218MA87	Escherichia_phage	1.2e-81	47.3
WP_005332611.1\|1408412_1409219_-	siderophore-interacting protein	NA	NA	NA	NA
WP_081805651.1\|1409350_1410766_-	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_005332602.1\|1410768_1412808_-	MacB family efflux pump subunit	G9BWD6	Planktothrix_phage	9.2e-35	39.9
WP_005332598.1\|1412804_1413968_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_005332596.1\|1414211_1414652_-	universal stress protein	NA	NA	NA	NA
WP_005332594.1\|1415049_1415931_-	pyrophosphatase	NA	NA	NA	NA
WP_005332592.1\|1416466_1418131_-	DNA repair protein RecN	NA	NA	NA	NA
WP_005332588.1\|1418465_1419626_+	GGDEF domain-containing protein	A0A127AWB9	Bacillus_phage	4.2e-16	31.7
WP_005332581.1\|1419665_1420550_-	NAD(+) kinase	NA	NA	NA	NA
WP_025327678.1\|1420813_1421389_+	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_041205360.1\|1421723_1423649_+	molecular chaperone DnaK	A0A0N9QXN8	Chrysochromulina_ericina_virus	1.1e-151	51.0
WP_005330311.1\|1423917_1425054_+	molecular chaperone DnaJ	E3T4P7	Cafeteria_roenbergensis_virus	3.1e-24	35.1
WP_005330309.1\|1425322_1426807_+	carbohydrate porin	NA	NA	NA	NA
WP_081805653.1\|1426919_1427897_+	aminoimidazole riboside kinase	NA	NA	NA	NA
WP_005330304.1\|1427968_1429333_+	PTS sucrose transporter subunit IIBC	NA	NA	NA	NA
WP_005330303.1\|1429332_1430748_+	sucrose-6-phosphate hydrolase	NA	NA	NA	NA
WP_005330302.1\|1430775_1431786_+	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_042649827.1\|1431872_1432601_-	MgtC/SapB family protein	G3MA03	Bacillus_virus	1.5e-11	39.3
WP_004576012.1\|1432757_1434176_+\|transposase	IS66-like element ISAs21 family transposase	NA	NA	NA	NA
WP_041205364.1\|1434361_1434766_-	hypothetical protein	NA	NA	NA	NA
WP_005330299.1\|1435131_1435317_-	DUF2892 domain-containing protein	NA	NA	NA	NA
WP_005330298.1\|1435402_1435717_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_005330289.1\|1435713_1436127_+	YeeE/YedE family protein	NA	NA	NA	NA
WP_039039223.1\|1436140_1436587_+	YeeE/YedE family protein	NA	NA	NA	NA
WP_041205365.1\|1436626_1437646_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_161506966.1\|1437638_1440797_+	efflux RND transporter permease subunit	NA	NA	NA	NA
WP_041205366.1\|1440830_1443275_-	diguanylate cyclase	G3MA91	Bacillus_virus	4.8e-22	36.2
WP_041205367.1\|1443685_1444699_+	lipoate--protein ligase	NA	NA	NA	NA
WP_081805654.1\|1445563_1445980_-\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	4.9e-44	60.1
WP_041205370.1\|1446001_1447207_+\|transposase	transposase	A0A1B0VCD8	Salmonella_phage	1.2e-135	61.1
WP_161506967.1\|1448360_1449326_-\|transposase	IS1595-like element ISAeme10 family transposase	NA	NA	NA	NA

DBSCAN-SWA_7

1463824 : 1664884

163

Helicobacter_phage(21.95%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_103261424.1\|1463824_1464229_-\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	3.3e-29	54.0
WP_103261423.1\|1464286_1465513_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	O80301	Enterobacteria_phage	7.7e-154	78.6
WP_080989979.1\|1465547_1466534_+	nucleoside hydrolase	NA	NA	NA	NA
WP_039039207.1\|1466629_1466959_+	DUF3634 family protein	NA	NA	NA	NA
WP_052815582.1\|1467049_1467958_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_160839189.1\|1468888_1469971_+	cytochrome o ubiquinol oxidase subunit II	NA	NA	NA	NA
WP_041211612.1\|1469974_1471951_+	cytochrome o ubiquinol oxidase subunit I	NA	NA	NA	NA
WP_080989981.1\|1471871_1472567_+	cytochrome o ubiquinol oxidase subunit III	NA	NA	NA	NA
WP_010673684.1\|1472567_1472897_+	cytochrome o ubiquinol oxidase subunit IV	NA	NA	NA	NA
WP_010673685.1\|1472905_1473799_+	protoheme IX farnesyltransferase	NA	NA	NA	NA
WP_113978023.1\|1473963_1475325_+	MFS transporter	NA	NA	NA	NA
WP_010673687.1\|1475408_1475777_+	DUF1428 domain-containing protein	NA	NA	NA	NA
WP_041205253.1\|1475881_1477219_-\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_041205389.1\|1477342_1478446_-	YdcF family protein	NA	NA	NA	NA
WP_005332127.1\|1478595_1479489_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_081805658.1\|1479589_1480078_+	hypothetical protein	NA	NA	NA	NA
WP_161506973.1\|1480088_1480517_+	hypothetical protein	NA	NA	NA	NA
WP_005332143.1\|1480795_1481038_-	DUF3297 family protein	NA	NA	NA	NA
WP_161506974.1\|1481136_1482453_-	type II toxin-antitoxin system HipA family toxin	NA	NA	NA	NA
WP_049832154.1\|1482436_1482733_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_019706001.1\|1483236_1484184_-\|transposase	IS30-like element ISAs2 family transposase	Q9MBM9	Staphylococcus_prophage	1.4e-41	35.7
WP_148304709.1\|1484252_1484612_-\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	3.2e-15	49.4
WP_041206863.1\|1484645_1485785_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A077SLN2	Escherichia_phage	7.2e-146	68.7
WP_019706001.1\|1486286_1487234_+\|transposase	IS30-like element ISAs2 family transposase	Q9MBM9	Staphylococcus_prophage	1.4e-41	35.7
WP_005323482.1\|1488391_1489198_-	tryptophan synthase subunit alpha	NA	NA	NA	NA
WP_005323481.1\|1489194_1490388_-	tryptophan synthase subunit beta	NA	NA	NA	NA
WP_005323480.1\|1490442_1491930_-	bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF	A0A0P0IR83	Acinetobacter_phage	3.8e-38	42.3
WP_005323479.1\|1491926_1492940_-	anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	4.4e-54	38.7
WP_005323478.1\|1492949_1493549_-	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	1.2e-27	36.8
WP_005323477.1\|1493541_1495179_-	anthranilate synthase component 1	NA	NA	NA	NA
WP_005323476.1\|1495600_1496482_+	PHP domain-containing protein	NA	NA	NA	NA
WP_161506975.1\|1496611_1497232_+	threonylcarbamoyl-AMP synthase	NA	NA	NA	NA
WP_081805733.1\|1497158_1498106_+	segregation/condensation protein A	NA	NA	NA	NA
WP_005323473.1\|1498141_1498714_+	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	8.1e-21	36.3
WP_005323472.1\|1498824_1499748_+	23S rRNA pseudouridine(2605) synthase RluB	NA	NA	NA	NA
WP_005323471.1\|1500003_1500867_+	acyl-CoA thioesterase II	NA	NA	NA	NA
WP_005323470.1\|1500941_1502120_-	dicarboxylate/amino acid:cation symporter	NA	NA	NA	NA
WP_005323469.1\|1502237_1502897_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_005323466.1\|1502996_1503638_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_041206082.1\|1503790_1504984_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_041206081.1\|1505001_1508151_+	efflux RND transporter permease subunit	NA	NA	NA	NA
WP_041206080.1\|1508143_1509559_+	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_041205574.1\|1510122_1510548_-\|transposase	IS200/IS605-like element ISAeme8 family transposase	A0A1S5RHE3	Helicobacter_phage	4.9e-23	46.9
WP_041206863.1\|1510605_1511745_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A077SLN2	Escherichia_phage	7.2e-146	68.7
WP_041206683.1\|1512395_1513937_+\|transposase	IS21 family transposase	K4I413	Acidithiobacillus_phage	3.2e-128	47.2
WP_161506736.1\|1513951_1514707_+	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	6.8e-60	51.9
WP_041206074.1\|1516197_1516512_-	DNA-binding protein	NA	NA	NA	NA
WP_005328266.1\|1516517_1516853_-	addiction module protein	A0A141GEX6	Brucella_phage	2.0e-11	46.4
WP_041205574.1\|1517091_1517517_-\|transposase	IS200/IS605-like element ISAeme8 family transposase	A0A1S5RHE3	Helicobacter_phage	4.9e-23	46.9
WP_041206863.1\|1517574_1518714_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A077SLN2	Escherichia_phage	7.2e-146	68.7
WP_161507828.1\|1518813_1519350_+	recombinase family protein	E5FFF9	Burkholderia_phage	4.4e-21	36.8
WP_001809438.1\|1519451_1520483_+\|transposase	IS630-like element ISAhy2 family transposase	NA	NA	NA	NA
WP_005342491.1\|1520863_1521814_-\|transposase	IS1595-like element ISKpn3 family transposase	NA	NA	NA	NA
WP_161506976.1\|1522725_1523466_-	phosphatase	NA	NA	NA	NA
WP_005324182.1\|1523934_1524588_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_161506977.1\|1524635_1526960_+	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_161506978.1\|1527121_1530184_+	efflux RND transporter permease subunit	S5VTK5	Leptospira_phage	5.4e-71	25.3
WP_161506979.1\|1530199_1531243_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_005324189.1\|1531309_1532749_-	pyruvate kinase	NA	NA	NA	NA
WP_005324191.1\|1532921_1533779_-	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
WP_041205155.1\|1533976_1535245_+\|transposase	IS4-like element ISAeme3 family transposase	NA	NA	NA	NA
WP_039041241.1\|1535518_1536487_+	glucokinase	NA	NA	NA	NA
WP_041206069.1\|1536862_1538245_-	GHKL domain-containing protein	NA	NA	NA	NA
WP_041207018.1\|1538244_1538919_-	response regulator	W8CYM9	Bacillus_phage	2.8e-28	34.6
WP_099993964.1\|1541576_1542593_+\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	2.2e-186	99.4
WP_010674210.1\|1543877_1545491_-\|transposase	IS1634-like element ISAs25 family transposase	NA	NA	NA	NA
WP_004576012.1\|1545848_1547267_+\|transposase	IS66-like element ISAs21 family transposase	NA	NA	NA	NA
WP_041205384.1\|1547967_1549065_-\|transposase	ISAs1-like element ISAeme2 family transposase	NA	NA	NA	NA
WP_010674210.1\|1549467_1551081_-\|transposase	IS1634-like element ISAs25 family transposase	NA	NA	NA	NA
WP_004576012.1\|1551438_1552857_+\|transposase	IS66-like element ISAs21 family transposase	NA	NA	NA	NA
WP_041205384.1\|1553557_1554655_-\|transposase	ISAs1-like element ISAeme2 family transposase	NA	NA	NA	NA
WP_161507829.1\|1554730_1555186_+	hypothetical protein	A0A1V0SAG5	Catovirus	5.6e-09	40.6
WP_161506980.1\|1555202_1556474_+	hypothetical protein	NA	NA	NA	NA
WP_161506981.1\|1556448_1557609_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_161506982.1\|1557991_1558762_+	O-antigen ligase family protein	NA	NA	NA	NA
WP_161506983.1\|1558778_1559669_+	glycosyltransferase	NA	NA	NA	NA
WP_161506984.1\|1559713_1560553_+	glycosyltransferase	NA	NA	NA	NA
WP_161506985.1\|1561043_1562210_+	nucleotide sugar dehydrogenase	O41091	Paramecium_bursaria_Chlorella_virus	2.4e-112	54.5
WP_161506986.1\|1562527_1563649_+	polysaccharide export protein	NA	NA	NA	NA
WP_161506987.1\|1563712_1564141_+	protein tyrosine phosphatase	NA	NA	NA	NA
WP_161506988.1\|1564196_1566371_+	polysaccharide biosynthesis tyrosine autokinase	NA	NA	NA	NA
WP_161506989.1\|1567920_1569482_-\|transposase	IS3-like element ISAs20 family transposase	NA	NA	NA	NA
WP_161506990.1\|1570886_1571303_+\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	3.8e-44	60.1
WP_161506991.1\|1571818_1572490_+	YjbF family lipoprotein	NA	NA	NA	NA
WP_161506992.1\|1572486_1573242_+	hypothetical protein	NA	NA	NA	NA
WP_161506993.1\|1573238_1575323_+	YjbH domain-containing protein	NA	NA	NA	NA
WP_161506994.1\|1575410_1577129_+	ligase	NA	NA	NA	NA
WP_161506995.1\|1577305_1577758_+	hypothetical protein	NA	NA	NA	NA
WP_113720009.1\|1577938_1578592_+	DUF480 domain-containing protein	NA	NA	NA	NA
WP_161506996.1\|1578797_1582634_+	DEAD/DEAH box helicase	A0A160DHD3	Gordonia_phage	1.3e-45	28.8
WP_042649461.1\|1582753_1583647_-	DNA replication terminus site-binding protein	NA	NA	NA	NA
WP_005331430.1\|1584170_1584380_+	DUF1127 domain-containing protein	NA	NA	NA	NA
WP_161506997.1\|1584652_1585669_+	succinylglutamate desuccinylase	NA	NA	NA	NA
WP_005331435.1\|1585930_1587028_+	pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha	NA	NA	NA	NA
WP_005331436.1\|1587096_1588083_+	alpha-ketoacid dehydrogenase subunit beta	A0A0K0KW14	Prochlorococcus_phage	1.8e-07	28.8
WP_005331438.1\|1589484_1589694_+	cold-shock protein	A0A1W6JNX5	Morganella_phage	1.1e-15	60.0
WP_041206056.1\|1589789_1590086_+	hypothetical protein	NA	NA	NA	NA
WP_025327553.1\|1590072_1590321_-	TIGR02647 family protein	NA	NA	NA	NA
WP_041206055.1\|1590569_1591127_+	hypothetical protein	NA	NA	NA	NA
WP_005331447.1\|1591221_1591614_+	DUF2750 domain-containing protein	NA	NA	NA	NA
WP_161506998.1\|1591700_1593551_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_005331452.1\|1593643_1594537_-	EamA family transporter	NA	NA	NA	NA
WP_005331455.1\|1594751_1594940_+	hypothetical protein	NA	NA	NA	NA
WP_021141233.1\|1595231_1595636_-\|transposase	IS200/IS605-like element ISAs26 family transposase	A0A1S5RHE3	Helicobacter_phage	8.8e-30	54.8
WP_021141234.1\|1595693_1596920_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	O80301	Enterobacteria_phage	7.7e-154	78.6
WP_081805727.1\|1596863_1597913_-	HD-GYP domain-containing protein	NA	NA	NA	NA
WP_041206053.1\|1598087_1598780_+	16S rRNA pseudouridine(516) synthase RsuA	NA	NA	NA	NA
WP_161506999.1\|1598890_1599880_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_005329750.1\|1600170_1601073_-	DMT family transporter	NA	NA	NA	NA
WP_041207011.1\|1601372_1603010_+	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_161507000.1\|1603020_1603575_+	phosphodiesterase	NA	NA	NA	NA
WP_161507001.1\|1603608_1604025_-	flagellar protein FlgN	NA	NA	NA	NA
WP_005329758.1\|1604021_1604342_-	flagellar biosynthesis anti-sigma factor FlgM	NA	NA	NA	NA
WP_161507002.1\|1604436_1605120_-	flagellar basal body P-ring formation protein FlgA	NA	NA	NA	NA
WP_161507003.1\|1605278_1606190_+	chemotaxis protein CheV	Q56AR1	Bacillus_thuringiensis_phage	7.5e-37	32.8
WP_005329773.1\|1606207_1607032_+	protein-glutamate O-methyltransferase	NA	NA	NA	NA
WP_161507004.1\|1607092_1607491_+	flagellar basal body rod protein FlgB	NA	NA	NA	NA
WP_005329775.1\|1607490_1607910_+	flagellar basal body rod protein FlgC	NA	NA	NA	NA
WP_042648969.1\|1608015_1608759_+	flagellar hook assembly protein FlgD	NA	NA	NA	NA
WP_161507005.1\|1608769_1610635_+	flagellar hook-basal body complex protein	NA	NA	NA	NA
WP_161507006.1\|1610781_1611528_+	flagellar basal-body rod protein FlgF	NA	NA	NA	NA
WP_005329779.1\|1611542_1612331_+	flagellar basal-body rod protein FlgG	NA	NA	NA	NA
WP_161507007.1\|1612357_1613029_+	flagellar basal body L-ring protein FlgH	NA	NA	NA	NA
WP_161507008.1\|1613090_1614188_+	flagellar basal body P-ring protein FlgI	NA	NA	NA	NA
WP_069652528.1\|1614234_1615335_+	flagellar assembly peptidoglycan hydrolase FlgJ	A0A0A7RU71	Clostridium_phage	3.4e-15	36.5
WP_161507009.1\|1615338_1617336_+	flagellar biosynthesis protein FlgK	NA	NA	NA	NA
WP_005329788.1\|1617339_1618548_+	flagellar hook-associated protein 3	NA	NA	NA	NA
WP_041205574.1\|1618788_1619214_-\|transposase	IS200/IS605-like element ISAeme8 family transposase	A0A1S5RHE3	Helicobacter_phage	4.9e-23	46.9
WP_012564931.1\|1620346_1621294_-\|transposase	IS30-like element ISAeca1 family transposase	Q9MBM9	Staphylococcus_prophage	1.0e-44	36.9
WP_021141233.1\|1623083_1623488_-\|transposase	IS200/IS605-like element ISAs26 family transposase	A0A1S5RHE3	Helicobacter_phage	8.8e-30	54.8
WP_021141234.1\|1623545_1624772_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	O80301	Enterobacteria_phage	7.7e-154	78.6
WP_041206049.1\|1625047_1626538_-	exopolyphosphatase	NA	NA	NA	NA
WP_005331929.1\|1626527_1628597_-	polyphosphate kinase 1	NA	NA	NA	NA
WP_005331931.1\|1628673_1629186_-	ACT domain-containing protein	NA	NA	NA	NA
WP_041206048.1\|1629444_1630284_+	DUF2726 domain-containing protein	NA	NA	NA	NA
WP_041206047.1\|1630523_1631942_+	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_161507010.1\|1632047_1633082_+	PAS domain-containing protein	NA	NA	NA	NA
WP_161507011.1\|1633137_1634472_+	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_161507012.1\|1634614_1635376_+	Nif3-like dinuclear metal center hexameric protein	NA	NA	NA	NA
WP_161507013.1\|1635494_1636133_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	3.5e-25	37.8
WP_139751091.1\|1636141_1637179_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	7.2e-76	46.5
WP_005302745.1\|1637354_1637981_+	uracil phosphoribosyltransferase	NA	NA	NA	NA
WP_161507014.1\|1638124_1639153_+	DUF2066 domain-containing protein	NA	NA	NA	NA
WP_005331956.1\|1639255_1639957_+	DnaA inactivator Hda	NA	NA	NA	NA
WP_004575061.1\|1640101_1641439_+\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_161507015.1\|1641491_1642805_-	isocitrate lyase	NA	NA	NA	NA
WP_161507016.1\|1642878_1644486_-	malate synthase A	NA	NA	NA	NA
WP_161507017.1\|1645925_1646465_+\|tRNA	tRNA adenosine(34) deaminase TadA	NA	NA	NA	NA
WP_161507018.1\|1646668_1648906_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_042649945.1\|1648923_1650573_+	phosphate ABC transporter permease PstA	NA	NA	NA	NA
WP_005328825.1\|1650793_1651612_+	phosphate ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.6e-22	32.1
WP_139751100.1\|1651702_1652413_+	phosphate signaling complex protein PhoU	NA	NA	NA	NA
WP_041206040.1\|1652606_1653926_+	HlyC/CorC family transporter	NA	NA	NA	NA
WP_161507019.1\|1653946_1654489_+	hypothetical protein	NA	NA	NA	NA
WP_161507020.1\|1654763_1655663_+	homocysteine S-methyltransferase family protein	NA	NA	NA	NA
WP_005328837.1\|1655672_1657073_+	amino acid permease	NA	NA	NA	NA
WP_041205358.1\|1657125_1658454_-\|transposase	IS4-like element ISAeme12 family transposase	NA	NA	NA	NA
WP_041207009.1\|1658573_1659413_-	sterol desaturase family protein	NA	NA	NA	NA
WP_041206038.1\|1659613_1660357_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.0e-36	38.7
WP_005330345.1\|1660446_1661406_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_005330342.1\|1661503_1662292_-	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_021141233.1\|1663195_1663600_-\|transposase	IS200/IS605-like element ISAs26 family transposase	A0A1S5RHE3	Helicobacter_phage	8.8e-30	54.8
WP_021141234.1\|1663657_1664884_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	O80301	Enterobacteria_phage	7.7e-154	78.6

DBSCAN-SWA_8

1685114 : 1728810

Klebsiella_phage(16.67%)

tRNA,integrase,transposase

attL 1672735:1672750|attR 1717916:1717931

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1672735:1672750	attL	NA	NA	NA	NA
WP_161507032.1\|1685114_1686452_+\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_161507033.1\|1686500_1688006_-	DUF853 family protein	A0A248XCZ8	Klebsiella_phage	6.5e-86	46.4
WP_161507034.1\|1688132_1688627_-	DUF2062 domain-containing protein	NA	NA	NA	NA
WP_161507035.1\|1688620_1689139_-	DUF2062 domain-containing protein	NA	NA	NA	NA
WP_161507830.1\|1689167_1691429_+	DNA internalization-related competence protein ComEC/Rec2	NA	NA	NA	NA
WP_005331991.1\|1691617_1693387_+	lipid A ABC transporter ATP-binding protein/permease MsbA	W8CYL7	Bacillus_phage	4.2e-60	30.5
WP_005331989.1\|1693386_1694382_+	tetraacyldisaccharide 4'-kinase	NA	NA	NA	NA
WP_005331987.1\|1694532_1694733_+	Trm112 family protein	NA	NA	NA	NA
WP_005331986.1\|1694729_1695479_+	3-deoxy-manno-octulosonate cytidylyltransferase	NA	NA	NA	NA
WP_041206003.1\|1695689_1696334_+	UvrY/SirA/GacA family response regulator transcription factor	NA	NA	NA	NA
WP_041206002.1\|1696445_1698299_+	excinuclease ABC subunit UvrC	NA	NA	NA	NA
WP_041206001.1\|1698592_1699147_+	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_161507036.1\|1699989_1701195_+\|integrase	site-specific integrase	Q19US1	Mannheimia_phage	6.5e-12	34.6
WP_161507037.1\|1701342_1701699_+	hypothetical protein	NA	NA	NA	NA
WP_161507038.1\|1701691_1702006_+	DUF1232 domain-containing protein	NA	NA	NA	NA
WP_011191341.1\|1702051_1703326_-\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA
WP_041205574.1\|1703809_1704235_-\|transposase	IS200/IS605-like element ISAeme8 family transposase	A0A1S5RHE3	Helicobacter_phage	4.9e-23	46.9
WP_041204928.1\|1705674_1706802_-\|transposase	ISAs1-like element ISKpn9 family transposase	NA	NA	NA	NA
WP_158319064.1\|1710420_1711050_+	hypothetical protein	NA	NA	NA	NA
WP_041205997.1\|1711390_1712014_+	glutathione S-transferase	NA	NA	NA	NA
WP_005330893.1\|1712220_1712469_-	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_005330895.1\|1712589_1713318_-	UDP-2,3-diacylglucosamine diphosphatase	NA	NA	NA	NA
WP_005330897.1\|1713314_1714028_-	DUF4269 domain-containing protein	NA	NA	NA	NA
WP_005330899.1\|1714017_1714515_-	peptidyl-prolyl cis-trans isomerase	NA	NA	NA	NA
WP_005330901.1\|1714718_1716095_+\|tRNA	cysteine--tRNA ligase	H2EDD6	Moumouvirus	1.0e-45	30.0
WP_004576012.1\|1716716_1718135_+\|transposase	IS66-like element ISAs21 family transposase	NA	NA	NA	NA
1717916:1717931	attR	NA	NA	NA	NA
WP_041204928.1\|1719275_1720403_+\|transposase	ISAs1-like element ISKpn9 family transposase	NA	NA	NA	NA
WP_148304699.1\|1721146_1721839_-	hypothetical protein	NA	NA	NA	NA
WP_011191341.1\|1722214_1723489_-\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA
WP_107961366.1\|1724653_1725799_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_052814785.1\|1727199_1728810_-\|transposase	IS66 family transposase	A0A218MNE7	uncultured_virus	2.5e-43	32.8

DBSCAN-SWA_9

2002631 : 2024691

uncultured_Caudovirales_phage(20.0%)

integrase,transposase

attL 1996207:1996266|attR 2020425:2020515

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1996207:1996266	attL	NA	NA	NA	NA
WP_041205618.1\|2002631_2005010_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_161507133.1\|2004994_2008303_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_010674971.1\|2008793_2008994_-	helix-turn-helix transcriptional regulator	A0A2H4JGT9	uncultured_Caudovirales_phage	1.5e-06	36.9
WP_010674970.1\|2009119_2009335_+	hypothetical protein	NA	NA	NA	NA
WP_161507134.1\|2009350_2010595_+\|integrase	site-specific integrase	A0A1W6JTA0	Pseudomonas_phage	3.8e-39	29.1
WP_104453295.1\|2010716_2011469_+	HDOD domain-containing protein	NA	NA	NA	NA
WP_010674967.1\|2011593_2011875_+	hypothetical protein	NA	NA	NA	NA
WP_160839242.1\|2012272_2012518_+	hypothetical protein	NA	NA	NA	NA
WP_024943279.1\|2012576_2012927_+	toxin RelE	NA	NA	NA	NA
WP_042648333.1\|2012926_2013229_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_099368881.1\|2013452_2014469_-\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	2.2e-186	99.4
WP_161507135.1\|2014510_2015653_-\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_005330546.1\|2015788_2016373_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_161507841.1\|2016381_2018940_+	DEAD/DEAH box helicase family protein	G9FI19	Nocardia_phage	1.0e-30	32.8
WP_161507136.1\|2019048_2020266_-	J domain-containing protein	NA	NA	NA	NA
WP_005329232.1\|2020943_2022254_-	type II toxin-antitoxin system HipA family toxin	NA	NA	NA	NA
2020425:2020515	attR	NA	NA	NA	NA
WP_005329233.1\|2022253_2022508_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_161507132.1\|2023009_2023258_+	hypothetical protein	NA	NA	NA	NA
WP_005328758.1\|2023773_2024691_+\|transposase	IS5-like element ISAeme7 family transposase	A0A1V0E8E1	Vibrio_phage	2.6e-93	56.5

DBSCAN-SWA_10

2107041 : 2201516

Bacillus_phage(38.46%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041205253.1\|2107041_2108379_-\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_161507149.1\|2108490_2109426_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_005327914.1\|2109587_2111852_+	5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase	NA	NA	NA	NA
WP_161507150.1\|2112216_2113353_+	HPP family protein	NA	NA	NA	NA
WP_041205644.1\|2115490_2116165_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_005327907.1\|2116236_2117490_-	D-amino acid dehydrogenase	NA	NA	NA	NA
WP_161507151.1\|2117643_2119164_-	cryptochrome/photolyase family protein	E3T4R9	Cafeteria_roenbergensis_virus	2.7e-47	31.8
WP_005327905.1\|2119163_2119307_-	DUF2256 domain-containing protein	NA	NA	NA	NA
WP_005327904.1\|2119478_2120399_-	peptidase S11	NA	NA	NA	NA
WP_005327903.1\|2120749_2121940_-	heme lyase NrfEFG subunit NrfF	NA	NA	NA	NA
WP_005327902.1\|2121936_2122512_-	DsbE family thiol:disulfide interchange protein	NA	NA	NA	NA
WP_005327901.1\|2122508_2124470_-	heme lyase NrfEFG subunit NrfE	NA	NA	NA	NA
WP_005327900.1\|2124619_2125573_-	cytochrome c nitrite reductase subunit NrfD	NA	NA	NA	NA
WP_005327898.1\|2125660_2126341_-	cytochrome c nitrite reductase Fe-S protein	NA	NA	NA	NA
WP_041205646.1\|2126337_2126991_-	cytochrome c nitrite reductase pentaheme subunit	NA	NA	NA	NA
WP_041205647.1\|2127042_2128485_-	ammonia-forming nitrite reductase cytochrome c552 subunit	NA	NA	NA	NA
WP_005327893.1\|2140028_2141231_-	anaerobic glycerol-3-phosphate dehydrogenase subunit C	NA	NA	NA	NA
WP_041205648.1\|2141334_2142612_-	glycerol-3-phosphate dehydrogenase subunit GlpB	NA	NA	NA	NA
WP_139751787.1\|2142601_2144284_-	anaerobic glycerol-3-phosphate dehydrogenase subunit A	NA	NA	NA	NA
WP_139751788.1\|2144617_2145073_-	SecC motif-containing protein	NA	NA	NA	NA
WP_041205651.1\|2145201_2146869_+	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	9.8e-43	39.5
WP_005327887.1\|2146973_2148185_+	ROK family protein	NA	NA	NA	NA
WP_005327886.1\|2148181_2149765_+	sensor histidine kinase	NA	NA	NA	NA
WP_005327885.1\|2149765_2150431_+	response regulator	W8CYM9	Bacillus_phage	1.6e-07	36.9
WP_041205828.1\|2151163_2152501_+\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_025327141.1\|2153474_2153936_-	tripartite tricarboxylate transporter TctB family protein	NA	NA	NA	NA
WP_005327879.1\|2153978_2154944_-	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_041205653.1\|2155149_2156667_-	lytic transglycosylase F	A0A1P8CWQ1	Bacillus_phage	9.0e-11	43.3
WP_005327876.1\|2156871_2158557_-	aspartate:alanine antiporter	NA	NA	NA	NA
WP_005327874.1\|2158984_2159191_+	hypothetical protein	NA	NA	NA	NA
WP_041205655.1\|2159537_2161550_+	excinuclease ABC subunit UvrB	NA	NA	NA	NA
WP_041205657.1\|2161546_2161804_+	DUF1232 domain-containing protein	NA	NA	NA	NA
WP_005327863.1\|2161884_2162535_+	DedA family protein	NA	NA	NA	NA
WP_041205661.1\|2163043_2163565_-	disulfide bond formation protein DsbB	NA	NA	NA	NA
WP_041205664.1\|2163651_2165229_-	Na(+)/H(+) antiporter NhaB	NA	NA	NA	NA
WP_041205666.1\|2165562_2166276_+	fatty acid metabolism transcriptional regulator FadR	NA	NA	NA	NA
WP_139751786.1\|2166336_2167857_-	SpoVR family protein	NA	NA	NA	NA
WP_005327855.1\|2167867_2169139_-	YeaH/YhbH family protein	A0A140HLI1	Bacillus_phage	7.6e-11	36.7
WP_005327853.1\|2169163_2171086_-	PrkA family serine protein kinase	NA	NA	NA	NA
WP_041205668.1\|2171647_2173570_-	RecQ family ATP-dependent DNA helicase	A0A2K9L3P7	Tupanvirus	2.9e-54	35.5
WP_041205671.1\|2173906_2175157_+	serine/threonine transporter SstT	NA	NA	NA	NA
WP_005327845.1\|2175918_2177217_-	HAAAP family serine/threonine permease	NA	NA	NA	NA
WP_010676219.1\|2177392_2178490_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_041206924.1\|2178630_2179221_-	CoA pyrophosphatase	NA	NA	NA	NA
WP_049832177.1\|2179276_2180653_-	aminodeoxychorismate synthase component I	A0A0B5J984	Pandoravirus	2.4e-47	43.6
WP_005323523.1\|2180862_2182386_+	fumarate hydratase	NA	NA	NA	NA
WP_005323524.1\|2182546_2183026_-	hypothetical protein	NA	NA	NA	NA
WP_005323525.1\|2183259_2183457_+	DUF4250 domain-containing protein	NA	NA	NA	NA
WP_021141311.1\|2183792_2184929_+\|transposase	ISAs1-like element ISAs12 family transposase	NA	NA	NA	NA
WP_005323527.1\|2185304_2187779_+	glycogen/starch/alpha-glucan phosphorylase	Q8B3H5	Iris_mild_mosaic_virus	2.0e-15	45.6
WP_041205253.1\|2187893_2189231_+\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_005323528.1\|2189282_2189837_-	cytochrome b561	NA	NA	NA	NA
WP_005323530.1\|2190138_2191524_-	DASS family sodium-coupled anion symporter	NA	NA	NA	NA
WP_041205674.1\|2191678_2192119_-	thioredoxin TrxC	A0A1J0GW78	Streptomyces_phage	2.6e-11	40.4
WP_005323534.1\|2192273_2195072_+	response regulator	A0A1V0SGX0	Hokovirus	1.3e-66	34.0
WP_041205675.1\|2195215_2196952_+	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	2.9e-53	31.4
WP_005323542.1\|2197061_2198813_+	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	3.7e-48	30.5
WP_161507152.1\|2198874_2200056_-	hypothetical protein	NA	NA	NA	NA
WP_041205447.1\|2200349_2201516_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A077SLN2	Escherichia_phage	7.4e-146	67.9

DBSCAN-SWA_11

2253172 : 2389669

111

Hokovirus(12.0%)

tRNA,integrase,protease,transposase

attL 2366041:2366056|attR 2393279:2393294

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041205828.1\|2253172_2254510_+\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_161507155.1\|2254552_2255818_-	long-chain fatty acid transporter	NA	NA	NA	NA
WP_005325140.1\|2256226_2256970_-	DUF3379 domain-containing protein	NA	NA	NA	NA
WP_005325142.1\|2256962_2257478_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_041206927.1\|2257593_2259114_-	hypothetical protein	NA	NA	NA	NA
WP_161507156.1\|2259143_2260619_-	VWA domain-containing protein	NA	NA	NA	NA
WP_005325155.1\|2260640_2261600_-	VWA domain-containing protein	NA	NA	NA	NA
WP_041205724.1\|2261596_2262160_-	DUF4381 family protein	NA	NA	NA	NA
WP_041205726.1\|2262144_2263035_-	DUF58 domain-containing protein	NA	NA	NA	NA
WP_005325158.1\|2263158_2264109_-	AAA family ATPase	NA	NA	NA	NA
WP_005325159.1\|2264303_2265614_+	acetyl-CoA C-acyltransferase FadI	NA	NA	NA	NA
WP_041206928.1\|2265613_2267761_+	fatty acid oxidation complex subunit alpha FadJ	NA	NA	NA	NA
WP_005325161.1\|2268035_2268176_+	TIGR02808 family protein	NA	NA	NA	NA
WP_042648052.1\|2268365_2268923_+	YaeQ family protein	NA	NA	NA	NA
WP_161507157.1\|2268935_2269820_+	AEC family transporter	NA	NA	NA	NA
WP_012564931.1\|2269943_2270891_-\|transposase	IS30-like element ISAeca1 family transposase	Q9MBM9	Staphylococcus_prophage	1.0e-44	36.9
WP_161507158.1\|2271073_2271559_+	hypothetical protein	NA	NA	NA	NA
WP_161507159.1\|2271626_2272211_+	hypothetical protein	NA	NA	NA	NA
WP_161507160.1\|2272336_2273566_-	MFS transporter	NA	NA	NA	NA
WP_161507161.1\|2273630_2274398_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	3.2e-12	24.6
WP_161507162.1\|2274390_2275443_-	iron ABC transporter permease	NA	NA	NA	NA
WP_161507163.1\|2275562_2276669_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_161507164.1\|2277220_2280439_+	ExeM/NucH family extracellular endonuclease	NA	NA	NA	NA
WP_005326114.1\|2280606_2281146_-	glycine zipper 2TM domain-containing protein	NA	NA	NA	NA
WP_161507165.1\|2281493_2283116_+	acyl-CoA synthetase	A0A2H4PQU7	Staphylococcus_phage	1.8e-25	24.5
WP_161507166.1\|2283292_2284024_+	YafY family transcriptional regulator	NA	NA	NA	NA
WP_161507167.1\|2284090_2284411_+	hypothetical protein	NA	NA	NA	NA
WP_041205732.1\|2284512_2285148_-	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE	A0A2H4UVM0	Bodo_saltans_virus	7.9e-17	34.2
WP_161507168.1\|2285140_2285914_-	imidazole glycerol phosphate synthase subunit HisF	NA	NA	NA	NA
WP_161507169.1\|2286116_2290058_-	PAS domain S-box protein	A0A1V0SGX0	Hokovirus	2.7e-51	35.1
WP_139750895.1\|2290054_2292205_-	PAS domain S-box protein	NA	NA	NA	NA
WP_042650180.1\|2292197_2293307_-	two-component system response regulator	W8CYM9	Bacillus_phage	3.6e-09	36.4
WP_005325000.1\|2293458_2294193_-	1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase	A0A2H4UVM0	Bodo_saltans_virus	7.7e-08	22.8
WP_042650179.1\|2294198_2294831_-	imidazole glycerol phosphate synthase subunit HisH	NA	NA	NA	NA
WP_042650178.1\|2294830_2295964_-	bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB	NA	NA	NA	NA
WP_042650177.1\|2295976_2297077_-	histidinol-phosphate transaminase	NA	NA	NA	NA
WP_042650176.1\|2297073_2298384_-	histidinol dehydrogenase	NA	NA	NA	NA
WP_005324991.1\|2298396_2299293_-	ATP phosphoribosyltransferase	NA	NA	NA	NA
WP_041205737.1\|2299631_2299877_+	hypothetical protein	NA	NA	NA	NA
WP_005324987.1\|2299943_2301854_+	ATP-dependent DNA helicase	A0A127AW80	Bacillus_phage	2.5e-90	31.6
WP_005324985.1\|2302006_2302708_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA
WP_042650175.1\|2302775_2303294_+	Slp family lipoprotein	NA	NA	NA	NA
WP_042650174.1\|2303293_2304136_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_081805875.1\|2304332_2306009_+	long-chain-fatty-acid--CoA ligase FadD	A0A2H4PQM9	Staphylococcus_phage	9.6e-38	25.1
WP_161507170.1\|2306109_2307222_+	ribonuclease D	NA	NA	NA	NA
WP_161507171.1\|2307724_2308477_+	hypothetical protein	NA	NA	NA	NA
WP_161507172.1\|2308466_2309594_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_161507173.1\|2309970_2310408_+	hypothetical protein	NA	NA	NA	NA
WP_161507842.1\|2310681_2311050_-	conjugal transfer protein TraR	NA	NA	NA	NA
WP_161507174.1\|2311248_2312411_-\|transposase	IS3 family transposase	Q716C2	Shigella_phage	2.0e-82	50.3
WP_004576012.1\|2313148_2314567_+\|transposase	IS66-like element ISAs21 family transposase	NA	NA	NA	NA
WP_161506800.1\|2316364_2317452_-\|transposase	IS3-like element ISAeme6 family transposase	NA	NA	NA	NA
WP_161507175.1\|2317490_2318327_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_042650170.1\|2318383_2319328_-\|tRNA	tRNA dihydrouridine(16) synthase DusC	NA	NA	NA	NA
WP_161507176.1\|2319505_2319883_+	DUF454 domain-containing protein	NA	NA	NA	NA
WP_042650168.1\|2320015_2320561_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	3.4e-29	40.9
WP_041205745.1\|2320734_2323254_+	DNA polymerase III subunit gamma/tau	E7DN81	Pneumococcus_phage	7.9e-44	39.4
WP_011706069.1\|2323384_2323714_+	YbaB/EbfC family nucleoid-associated protein	NA	NA	NA	NA
WP_043131365.1\|2324240_2324867_-	hydrolase	NA	NA	NA	NA
WP_161507177.1\|2325031_2325898_-	pirin family protein	NA	NA	NA	NA
WP_161507843.1\|2325995_2326886_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_005330645.1\|2326969_2328292_-	YjiH family protein	NA	NA	NA	NA
WP_011191341.1\|2328703_2329978_+\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA
WP_019706001.1\|2330527_2331475_+\|transposase	IS30-like element ISAs2 family transposase	Q9MBM9	Staphylococcus_prophage	1.4e-41	35.7
WP_005325086.1\|2332377_2332800_+	CBS domain-containing protein	NA	NA	NA	NA
WP_161507178.1\|2332976_2336903_+	ATP-dependent RNA helicase HrpA	A0A1V0SBU4	Catovirus	1.1e-55	27.4
WP_041205747.1\|2337001_2337844_+	hypothetical protein	NA	NA	NA	NA
WP_041205748.1\|2338007_2338295_+	50S ribosomal protein L25	NA	NA	NA	NA
WP_161507179.1\|2338498_2341669_+	response regulator	A0A1V0SGX0	Hokovirus	3.6e-62	31.3
WP_042650066.1\|2341665_2342682_+	response regulator	W8CYM9	Bacillus_phage	3.2e-12	33.9
WP_042650067.1\|2342657_2343302_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_161507180.1\|2343295_2344426_-\|tRNA	tRNA 2-selenouridine(34) synthase MnmH	NA	NA	NA	NA
WP_041205752.1\|2344478_2345516_-	selenide, water dikinase SelD	NA	NA	NA	NA
WP_005328336.1\|2345844_2346489_+	glutathione S-transferase family protein	NA	NA	NA	NA
WP_005328337.1\|2346902_2348096_-	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_161507181.1\|2348309_2349740_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	1.1e-18	33.3
WP_005328342.1\|2349823_2350096_+	acylphosphatase	NA	NA	NA	NA
WP_161507182.1\|2350115_2350859_+	CHAD domain-containing protein	NA	NA	NA	NA
WP_042650070.1\|2350926_2352960_-\|tRNA	methionine--tRNA ligase	A0A1V0SEZ7	Hokovirus	2.9e-44	26.5
WP_005328348.1\|2353145_2354228_+	iron-sulfur cluster carrier protein ApbC	NA	NA	NA	NA
WP_041205758.1\|2354336_2354981_+	uridine kinase	A0A1V0SAA3	Catovirus	3.0e-32	38.0
WP_005328350.1\|2355044_2355626_+	dCTP deaminase	I4AZP2	Saccharomonospora_phage	9.1e-28	39.5
WP_041205760.1\|2355974_2357447_+	inorganic phosphate transporter	NA	NA	NA	NA
WP_041206683.1\|2357754_2359296_+\|transposase	IS21 family transposase	K4I413	Acidithiobacillus_phage	3.2e-128	47.2
WP_161507183.1\|2360704_2363878_-	ribonuclease E	NA	NA	NA	NA
WP_111910603.1\|2364252_2365236_+	23S rRNA pseudouridine(955/2504/2580) synthase RluC	NA	NA	NA	NA
WP_161507184.1\|2365235_2365883_+	HAD-IA family hydrolase	NA	NA	NA	NA
WP_041205765.1\|2365955_2366537_-	septum formation inhibitor Maf	NA	NA	NA	NA
2366041:2366056	attL	NA	NA	NA	NA
WP_041205768.1\|2366681_2367335_+	hypothetical protein	NA	NA	NA	NA
WP_025326977.1\|2367605_2368127_+	23S rRNA accumulation protein YceD	NA	NA	NA	NA
WP_005300935.1\|2368147_2368315_+	50S ribosomal protein L32	NA	NA	NA	NA
WP_041205769.1\|2368324_2369344_+	phosphate acyltransferase PlsX	NA	NA	NA	NA
WP_005329561.1\|2369350_2370310_+	ketoacyl-ACP synthase III	NA	NA	NA	NA
WP_041205773.1\|2370376_2371312_+	ACP S-malonyltransferase	NA	NA	NA	NA
WP_025326981.1\|2371325_2372060_+	3-oxoacyl-ACP reductase FabG	Q06VL0	Trichoplusia_ni_ascovirus	9.7e-19	34.7
WP_005300909.1\|2372217_2372454_+	acyl carrier protein	B2ZXV3	Ralstonia_phage	1.7e-09	47.1
WP_042648386.1\|2372536_2373778_+	beta-ketoacyl-ACP synthase II	NA	NA	NA	NA
WP_161507185.1\|2373845_2374652_+	aminodeoxychorismate lyase	NA	NA	NA	NA
WP_005329567.1\|2374641_2375643_+	endolytic transglycosylase MltG	NA	NA	NA	NA
WP_041205780.1\|2375642_2376284_+	dTMP kinase	A0A1L2BX49	Bacteriophage	8.2e-30	42.4
WP_005329570.1\|2376268_2377216_+	DNA polymerase III subunit delta'	B2ZY37	Ralstonia_phage	3.5e-05	27.5
WP_005329573.1\|2377234_2378014_+	YchF/TatD family DNA exonuclease	NA	NA	NA	NA
WP_161507844.1\|2378340_2379330_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_139751745.1\|2379542_2379800_+	hypothetical protein	NA	NA	NA	NA
WP_139751744.1\|2379995_2381426_-	16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF	NA	NA	NA	NA
WP_139750695.1\|2381555_2384108_-	MCE family protein	NA	NA	NA	NA
WP_139750696.1\|2384163_2384772_-	paraquat-inducible protein A	NA	NA	NA	NA
WP_139750697.1\|2384749_2385394_-	paraquat-inducible protein A	NA	NA	NA	NA
WP_139750698.1\|2385618_2385924_+	multidrug DMT transporter permease	NA	NA	NA	NA
WP_139750699.1\|2386213_2387491_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_161507186.1\|2387692_2389669_+\|protease	Lon protease family protein	NA	NA	NA	NA
2393279:2393294	attR	NA	NA	NA	NA

DBSCAN-SWA_12

2436300 : 2447424

Hokovirus(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_161507845.1\|2436300_2440227_-	transporter substrate-binding domain-containing protein	A0A1V0SGX0	Hokovirus	4.1e-31	35.6
WP_005300715.1\|2440281_2440578_-	integration host factor subunit alpha	A0A0H3UZA0	Geobacillus_virus	3.0e-11	35.6
WP_161507199.1\|2440581_2442969_-\|tRNA	phenylalanine--tRNA ligase subunit beta	A0A1L3IZU3	BeAn_58058_virus	1.1e-05	24.5
WP_005329694.1\|2442981_2443965_-\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2H4UW22	Bodo_saltans_virus	5.3e-36	38.2
WP_010674800.1\|2444289_2444646_-	50S ribosomal protein L20	NA	NA	NA	NA
WP_005315535.1\|2444660_2444858_-	50S ribosomal protein L35	NA	NA	NA	NA
WP_041204270.1\|2444943_2445492_-	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	1.8e-14	37.2
WP_043131783.1\|2445495_2447424_-\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	9.7e-127	38.0

DBSCAN-SWA_13

2621922 : 2683335

Bacillus_virus(20.0%)

tRNA,protease,bacteriocin,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041204923.1\|2621922_2623065_-\|transposase	IS4-like element ISAs18 family transposase	NA	NA	NA	NA
WP_004576012.1\|2624689_2626108_-\|transposase	IS66-like element ISAs21 family transposase	NA	NA	NA	NA
WP_042650400.1\|2627306_2628896_-	glutamine-hydrolyzing GMP synthase	NA	NA	NA	NA
WP_042650401.1\|2628980_2630444_-	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	9.1e-93	39.6
WP_161507245.1\|2630719_2631355_-	YitT family protein	NA	NA	NA	NA
WP_161507847.1\|2631985_2635081_-	alpha-amylase	NA	NA	NA	NA
WP_161507246.1\|2635575_2636490_+	EamA family transporter	NA	NA	NA	NA
WP_161507247.1\|2636651_2638016_+	exodeoxyribonuclease VII large subunit	A0A1B3AYB4	Gordonia_phage	7.8e-22	32.1
WP_161507248.1\|2638071_2639445_-	heme anaerobic degradation radical SAM methyltransferase ChuW/HutW	NA	NA	NA	NA
WP_161507249.1\|2639694_2640183_-	OmpA family protein	NA	NA	NA	NA
WP_161507250.1\|2640211_2641453_-	diguanylate cyclase	G3MA91	Bacillus_virus	2.1e-18	35.3
WP_041206956.1\|2641449_2641995_-	YfiR family protein	NA	NA	NA	NA
WP_042650408.1\|2642193_2643741_-	transcriptional regulator TyrR	NA	NA	NA	NA
WP_161507251.1\|2643887_2644226_-	4a-hydroxytetrahydrobiopterin dehydratase	NA	NA	NA	NA
WP_161507252.1\|2644274_2645069_-	phenylalanine 4-monooxygenase	NA	NA	NA	NA
WP_161507253.1\|2645289_2646321_-	TIGR01620 family protein	NA	NA	NA	NA
WP_161507254.1\|2646351_2647758_-	YcjX family protein	NA	NA	NA	NA
WP_161507255.1\|2647834_2648239_-	envelope stress response membrane protein PspC	NA	NA	NA	NA
WP_161507256.1\|2648235_2648472_-	envelope stress response membrane protein PspB	NA	NA	NA	NA
WP_041205885.1\|2648475_2649156_-	phage shock protein PspA	NA	NA	NA	NA
WP_161507257.1\|2649351_2650395_+	phage shock protein operon transcriptional activator	NA	NA	NA	NA
WP_161507848.1\|2650555_2652151_+	peptide ABC transporter substrate-binding protein SapA	NA	NA	NA	NA
WP_161507258.1\|2652227_2653187_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_161507259.1\|2653231_2654125_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_005325353.1\|2654335_2655334_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	2.8e-08	28.1
WP_005325357.1\|2655569_2656355_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.9e-13	28.9
WP_043131987.1\|2656500_2657259_-\|tRNA	tRNA hydroxylase	NA	NA	NA	NA
WP_161507849.1\|2657387_2658398_-	LacI family transcriptional regulator	NA	NA	NA	NA
WP_161507260.1\|2660128_2661559_+	6-phospho-beta-glucosidase	A0A0B5JD41	Pandoravirus	7.7e-36	27.0
WP_005325371.1\|2661665_2663186_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.8e-88	42.6
WP_005325372.1\|2663204_2663696_-\|bacteriocin	bacteriocin production protein	NA	NA	NA	NA
WP_043132095.1\|2663884_2665180_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	8.1e-93	50.7
WP_161507850.1\|2665467_2666811_-	replication-associated recombination protein A	G3MBE0	Bacillus_virus	5.4e-76	40.0
WP_042650317.1\|2666957_2667566_-	outer membrane lipoprotein chaperone LolA	NA	NA	NA	NA
WP_042650316.1\|2667635_2670140_-	DNA translocase FtsK	A0A218M9A2	Mycobacterium_phage	1.6e-89	49.6
WP_005300047.1\|2670332_2670824_-	leucine-responsive transcriptional regulator Lrp	NA	NA	NA	NA
WP_161507261.1\|2670974_2672090_+	alanine dehydrogenase	NA	NA	NA	NA
WP_043132103.1\|2672274_2673225_+	thioredoxin-disulfide reductase	A0A2I2L5E1	Orpheovirus	1.0e-60	43.8
WP_043132104.1\|2673281_2674523_+	response regulator	A0A127AWB9	Bacillus_phage	7.6e-16	32.8
WP_043132106.1\|2674625_2675096_-	glycine zipper 2TM domain-containing protein	NA	NA	NA	NA
WP_043132108.1\|2675113_2675821_+\|tRNA	leucyl/phenylalanyl-tRNA--protein transferase	NA	NA	NA	NA
WP_042650310.1\|2675817_2676534_+	arginyltransferase	NA	NA	NA	NA
WP_005300033.1\|2676602_2676821_+	translation initiation factor IF-1	NA	NA	NA	NA
WP_043132110.1\|2676890_2679143_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	7.0e-169	43.5
WP_005325410.1\|2679203_2679521_-\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	2.0e-13	46.9
WP_005300025.1\|2679749_2679968_+	cold shock-like protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	1.2e-17	63.2
WP_043132112.1\|2680093_2681206_-	aspartate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_043132113.1\|2681535_2681850_+	quaternary ammonium compound efflux SMR transporter SugE	NA	NA	NA	NA
WP_041205253.1\|2681997_2683335_+\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA

DBSCAN-SWA_14

2797309 : 2934144

110

Escherichia_phage(15.38%)

integrase,transposase

attL 2792664:2792681|attR 2907643:2907660

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2792664:2792681	attL	NA	NA	NA	NA
WP_099369027.1\|2797309_2798326_+\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	4.9e-186	99.1
WP_148304730.1\|2798386_2799328_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_041205490.1\|2800004_2801741_-	C4-dicarboxylic acid transporter DauA	A0A2H4J153	uncultured_Caudovirales_phage	1.0e-29	23.3
WP_021141311.1\|2801927_2803064_-\|transposase	ISAs1-like element ISAs12 family transposase	NA	NA	NA	NA
WP_161507312.1\|2804203_2805640_+	circularly permuted type 2 ATP-grasp protein	NA	NA	NA	NA
WP_005327429.1\|2805633_2806560_+	alpha-E domain-containing protein	NA	NA	NA	NA
WP_005327427.1\|2806556_2807357_+	transglutaminase family protein	NA	NA	NA	NA
WP_005327426.1\|2807373_2808075_+	peptidase	NA	NA	NA	NA
WP_041205479.1\|2808157_2808643_+	hypothetical protein	NA	NA	NA	NA
WP_005327423.1\|2808766_2809216_+	hypothetical protein	NA	NA	NA	NA
WP_041205476.1\|2809220_2812190_+	hypothetical protein	NA	NA	NA	NA
WP_005327419.1\|2812189_2813014_+	hypothetical protein	NA	NA	NA	NA
WP_005327418.1\|2813099_2814524_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_005327417.1\|2814664_2815225_+	hypothetical protein	NA	NA	NA	NA
WP_005327416.1\|2815331_2816591_+	hypothetical protein	NA	NA	NA	NA
WP_005327415.1\|2816678_2818325_+	hypothetical protein	NA	NA	NA	NA
WP_005327414.1\|2818441_2819644_+	Bcr/CflA family multidrug efflux MFS transporter	S4TR35	Salmonella_phage	1.2e-21	25.4
WP_041205474.1\|2819724_2820291_-	pyridoxamine 5'-phosphate oxidase family protein	NA	NA	NA	NA
WP_041205472.1\|2820320_2821748_-	sodium:proton antiporter	NA	NA	NA	NA
WP_005327410.1\|2821874_2822348_-	DUF4357 domain-containing protein	NA	NA	NA	NA
WP_005327408.1\|2822500_2823181_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.5e-29	35.0
WP_005327406.1\|2823202_2825623_+	FtsX-like permease family protein	NA	NA	NA	NA
WP_005327404.1\|2825619_2826693_+	carotenoid 1,2-hydratase	NA	NA	NA	NA
WP_099369027.1\|2826867_2827884_+\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	4.9e-186	99.1
WP_161507313.1\|2828091_2830884_-	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_041205467.1\|2830883_2831528_-	hypothetical protein	NA	NA	NA	NA
WP_005327547.1\|2831529_2832966_-	iron-sulfur cluster-binding protein	NA	NA	NA	NA
WP_081805666.1\|2832958_2833735_-	(Fe-S)-binding protein	NA	NA	NA	NA
WP_041205465.1\|2833747_2835445_-	L-lactate permease	NA	NA	NA	NA
WP_005327551.1\|2835580_2836486_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_041205463.1\|2836524_2837334_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_005327555.1\|2837442_2837814_+	MmcQ/YjbR family DNA-binding protein	NA	NA	NA	NA
WP_005327557.1\|2837819_2838356_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_041206878.1\|2838367_2838703_+	DUF3802 family protein	NA	NA	NA	NA
WP_005327561.1\|2838969_2839602_-	peptide-methionine (S)-S-oxide reductase MsrA	NA	NA	NA	NA
WP_041206877.1\|2839854_2841183_+	amino-acid N-acetyltransferase	NA	NA	NA	NA
WP_148304685.1\|2841356_2841536_-	hypothetical protein	NA	NA	NA	NA
WP_005327565.1\|2841600_2842953_+	lysine-sensitive aspartokinase 3	NA	NA	NA	NA
WP_041205459.1\|2843089_2844184_-	hypothetical protein	NA	NA	NA	NA
WP_161507314.1\|2844434_2846696_+	LTA synthase family protein	NA	NA	NA	NA
WP_012564931.1\|2847662_2848610_-\|transposase	IS30-like element ISAeca1 family transposase	Q9MBM9	Staphylococcus_prophage	1.0e-44	36.9
WP_005331601.1\|2849159_2849477_-	heavy metal-binding domain-containing protein	NA	NA	NA	NA
WP_005331597.1\|2850733_2852026_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_005331594.1\|2852100_2852640_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_005331593.1\|2852849_2854658_-	M3 family oligoendopeptidase	A0A1X9I5X5	Streptococcus_phage	1.6e-09	22.9
WP_041205454.1\|2856960_2857878_-	DUF808 domain-containing protein	NA	NA	NA	NA
WP_005331588.1\|2858088_2858691_+	DUF924 domain-containing protein	A0A1V0SIY0	Klosneuvirus	7.2e-20	35.3
WP_005331587.1\|2858770_2859676_-	protein translocase subunit SecF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.3e-33	33.7
WP_041205451.1\|2859785_2861555_-	protein translocase subunit SecD	NA	NA	NA	NA
WP_021141234.1\|2861616_2862843_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	O80301	Enterobacteria_phage	7.7e-154	78.6
WP_012564931.1\|2862945_2863893_-\|transposase	IS30-like element ISAeca1 family transposase	Q9MBM9	Staphylococcus_prophage	1.0e-44	36.9
WP_161507315.1\|2863960_2864398_+\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	1.6e-29	54.8
WP_041205447.1\|2864604_2865771_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A077SLN2	Escherichia_phage	7.4e-146	67.9
WP_041205445.1\|2865958_2866456_-	hypothetical protein	NA	NA	NA	NA
WP_041205443.1\|2866524_2867385_-	hypothetical protein	NA	NA	NA	NA
WP_139751046.1\|2867438_2868362_-	phosphotransferase	NA	NA	NA	NA
WP_041205438.1\|2868291_2868888_-	penicillin-binding protein activator LpoB	NA	NA	NA	NA
WP_041205436.1\|2868887_2869286_-	YcfL family protein	NA	NA	NA	NA
WP_005330108.1\|2869352_2870774_-	hypothetical protein	NA	NA	NA	NA
WP_005330109.1\|2870773_2871124_-	purine nucleoside phosphoramidase	NA	NA	NA	NA
WP_041205433.1\|2873469_2874345_-	6-pyruvoyltetrahydropterin synthase	A0A140B3P3	Vibrio_phage	1.4e-11	24.1
WP_005330115.1\|2874424_2875768_+	dihydroorotase	NA	NA	NA	NA
WP_049832155.1\|2876202_2876673_+	hypothetical protein	NA	NA	NA	NA
WP_005330120.1\|2876875_2878135_+	dicarboxylate/amino acid:cation symporter	NA	NA	NA	NA
WP_041205431.1\|2878191_2878638_-	isoprenylcysteine carboxylmethyltransferase family protein	NA	NA	NA	NA
WP_005326819.1\|2878814_2880041_+	alanine racemase	NA	NA	NA	NA
WP_005326821.1\|2880094_2881054_-	TerC family protein	A0A291LBC5	Escherichia_phage	6.1e-37	34.7
WP_005326823.1\|2881348_2882344_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.2e-21	33.3
WP_041205429.1\|2882343_2883324_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.9e-14	30.7
WP_005326827.1\|2883434_2884346_-	oligopeptide ABC transporter permease OppC	NA	NA	NA	NA
WP_041205427.1\|2884360_2885281_-	oligopeptide ABC transporter permease OppB	NA	NA	NA	NA
WP_161507316.1\|2885595_2887215_-	oligopeptide ABC transporter substrate-binding protein OppA	NA	NA	NA	NA
WP_041205423.1\|2887495_2888131_-	YchE family NAAT transporter	NA	NA	NA	NA
WP_005326838.1\|2889038_2891714_+	bifunctional acetaldehyde-CoA/alcohol dehydrogenase	NA	NA	NA	NA
WP_161507317.1\|2891824_2893060_+	DUF3391 domain-containing protein	NA	NA	NA	NA
WP_042649229.1\|2893412_2895104_+	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	4.8e-162	56.4
WP_139751416.1\|2895100_2895805_+	two-component system response regulator BtsR	NA	NA	NA	NA
WP_161507318.1\|2895947_2897369_+	carbon starvation protein A	NA	NA	NA	NA
WP_161507319.1\|2897440_2899075_-	mechanosensitive ion channel	NA	NA	NA	NA
WP_012564931.1\|2899196_2900144_-\|transposase	IS30-like element ISAeca1 family transposase	Q9MBM9	Staphylococcus_prophage	1.0e-44	36.9
WP_021141234.1\|2900432_2901659_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	O80301	Enterobacteria_phage	7.7e-154	78.6
WP_021141233.1\|2901716_2902121_+\|transposase	IS200/IS605-like element ISAs26 family transposase	A0A1S5RHE3	Helicobacter_phage	8.8e-30	54.8
WP_161507320.1\|2902192_2902525_+	DUF3302 domain-containing protein	NA	NA	NA	NA
WP_161507321.1\|2902534_2903572_+	HlyD family secretion protein	NA	NA	NA	NA
WP_161507322.1\|2903688_2905449_+	DEAD/DEAH box helicase	M4Q3N1	Vibrio_phage	1.7e-90	41.1
WP_161507323.1\|2905541_2906975_+	D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase	NA	NA	NA	NA
WP_161507324.1\|2907176_2907434_+	GrxA family glutaredoxin	A0A2I7SAE2	Vibrio_phage	2.8e-21	57.7
WP_005326862.1\|2907501_2907711_-	DUF1653 domain-containing protein	M5ABZ3	Bacillus_phage	2.6e-09	49.2
2907643:2907660	attR	NA	NA	NA	NA
WP_005326864.1\|2908070_2909285_+	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_139751411.1\|2910988_2912182_-	trans-2-enoyl-CoA reductase family protein	NA	NA	NA	NA
WP_005326867.1\|2912464_2912908_+	DUF4124 domain-containing protein	NA	NA	NA	NA
WP_161507325.1\|2913428_2914727_+	PAS domain S-box protein	A0A2H4J162	uncultured_Caudovirales_phage	1.2e-14	39.9
WP_161507326.1\|2914807_2915005_-	hypothetical protein	NA	NA	NA	NA
WP_161507327.1\|2915066_2915963_-	DMT family transporter	NA	NA	NA	NA
WP_005326871.1\|2916074_2916656_+	electron transport complex subunit RsxA	NA	NA	NA	NA
WP_161507328.1\|2916660_2917227_+	electron transport complex subunit RsxB	NA	NA	NA	NA
WP_161507329.1\|2917241_2919752_+	electron transport complex subunit RsxC	NA	NA	NA	NA
WP_161507330.1\|2919755_2920808_+	electron transport complex subunit RsxD	NA	NA	NA	NA
WP_139751791.1\|2920932_2921565_+	electron transport complex subunit RsxG	NA	NA	NA	NA
WP_161507331.1\|2921603_2922362_+	electron transport complex subunit E	NA	NA	NA	NA
WP_161507332.1\|2922392_2923034_+	endonuclease III	NA	NA	NA	NA
WP_025326535.1\|2923114_2923522_+	lactoylglutathione lyase	NA	NA	NA	NA
WP_161507333.1\|2925571_2926501_+	ZIP family metal transporter	NA	NA	NA	NA
WP_161507334.1\|2926642_2927335_+	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase	NA	NA	NA	NA
WP_161507335.1\|2927361_2928294_+	cobalamin biosynthesis protein CobD	NA	NA	NA	NA
WP_064339913.1\|2928286_2929150_+	cobalamin-binding protein	NA	NA	NA	NA
WP_005342491.1\|2929330_2930281_+\|transposase	IS1595-like element ISKpn3 family transposase	NA	NA	NA	NA
WP_161507336.1\|2930378_2930798_-	hypothetical protein	NA	NA	NA	NA
WP_019706001.1\|2931404_2932352_-\|transposase	IS30-like element ISAs2 family transposase	Q9MBM9	Staphylococcus_prophage	1.4e-41	35.7
WP_021141311.1\|2933007_2934144_-\|transposase	ISAs1-like element ISAs12 family transposase	NA	NA	NA	NA

DBSCAN-SWA_15

2940197 : 3005391

Enterobacteria_phage(30.77%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_161507342.1\|2940197_2941646_-\|tRNA	tRNA 4-thiouridine(8) synthase ThiI	NA	NA	NA	NA
WP_161507343.1\|2941821_2942781_+	hypothetical protein	NA	NA	NA	NA
WP_161507344.1\|2942853_2945253_-	penicillin-binding protein 1C	NA	NA	NA	NA
WP_161507853.1\|2945263_2950186_-	alpha-2-macroglobulin family protein	NA	NA	NA	NA
WP_161507345.1\|2950225_2951242_+	DUF2955 domain-containing protein	NA	NA	NA	NA
WP_161507346.1\|2951243_2951672_+	two pore domain potassium channel family protein	NA	NA	NA	NA
WP_161507347.1\|2951765_2953454_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_161507348.1\|2953588_2956528_+	EAL domain-containing protein	A0A127AWB9	Bacillus_phage	2.5e-09	28.1
WP_161507349.1\|2956603_2957446_+	pyruvate formate lyase 1-activating protein	M4MAG2	Vibrio_phage	9.2e-05	37.5
WP_161507350.1\|2957540_2958182_+	hypothetical protein	NA	NA	NA	NA
WP_005342491.1\|2959124_2960075_+\|transposase	IS1595-like element ISKpn3 family transposase	NA	NA	NA	NA
WP_011191341.1\|2960184_2961459_+\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA
WP_107961366.1\|2962024_2963170_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_161470123.1\|2963377_2963752_+	hypothetical protein	NA	NA	NA	NA
WP_041205394.1\|2965776_2966577_+	ABC transporter permease	NA	NA	NA	NA
WP_161507351.1\|2966599_2967250_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	6.8e-08	23.8
WP_161507352.1\|2967265_2968468_+	sugar transporter	NA	NA	NA	NA
WP_005342491.1\|2968549_2969500_+\|transposase	IS1595-like element ISKpn3 family transposase	NA	NA	NA	NA
WP_161507814.1\|2969638_2970910_-\|transposase	transposase	NA	NA	NA	NA
WP_161507353.1\|2971084_2973910_+	glycosyltransferase	NA	NA	NA	NA
WP_161507354.1\|2973909_2975574_+	hypothetical protein	NA	NA	NA	NA
WP_161507854.1\|2975612_2976779_+	nucleotide sugar dehydrogenase	M1I798	Paramecium_bursaria_Chlorella_virus	9.1e-112	54.9
WP_161507355.1\|2976863_2977766_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_161507356.1\|2977855_2979871_+	glycosyltransferase	NA	NA	NA	NA
WP_161507357.1\|2979858_2980887_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_161507358.1\|2980928_2981843_+	UTP--glucose-1-phosphate uridylyltransferase GalU	A0A127AW70	Bacillus_phage	7.5e-61	45.6
WP_161507359.1\|2981844_2982930_+	dTDP-glucose 4,6-dehydratase	A0A1D7XFE8	Escherichia_phage	1.3e-96	51.2
WP_161507360.1\|2982929_2983817_+	dTDP-4-dehydrorhamnose reductase	I7HXC9	Enterobacteria_phage	6.2e-28	35.7
WP_010676219.1\|2984636_2985734_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_041206088.1\|2986084_2986636_+	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	3.0e-49	55.9
WP_161507361.1\|2986686_2988771_+	capsular polysaccharide biosynthesis protein	NA	NA	NA	NA
WP_161507362.1\|2988778_2990092_+	capsular biosynthesis protein	NA	NA	NA	NA
WP_043130022.1\|2990268_2990961_-	ABC transporter permease	NA	NA	NA	NA
WP_005332892.1\|2991054_2991795_-	ABC transporter permease	NA	NA	NA	NA
WP_161507363.1\|2991999_2992773_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_161507364.1\|2992838_2993609_-	ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	1.7e-13	26.0
WP_041206091.1\|2994141_2995044_+	lysine exporter LysO family protein	NA	NA	NA	NA
WP_041207026.1\|2995250_2996579_+\|transposase	IS4-like element ISAeme13 family transposase	NA	NA	NA	NA
WP_021141234.1\|2996803_2998030_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	O80301	Enterobacteria_phage	7.7e-154	78.6
WP_021141233.1\|2998087_2998492_+\|transposase	IS200/IS605-like element ISAs26 family transposase	A0A1S5RHE3	Helicobacter_phage	8.8e-30	54.8
WP_005327633.1\|2998584_2998965_-	DUF2069 domain-containing protein	NA	NA	NA	NA
WP_041206093.1\|2998961_2999312_-	arsenate reductase (glutaredoxin)	NA	NA	NA	NA
WP_041206094.1\|2999370_2999850_+	TlpA family protein disulfide reductase	NA	NA	NA	NA
WP_041206095.1\|2999920_3001354_-	M48 family metallopeptidase	NA	NA	NA	NA
WP_005327624.1\|3001505_3001748_+	sulfurtransferase TusA family protein	NA	NA	NA	NA
WP_041206096.1\|3001828_3002899_+	AI-2E family transporter	NA	NA	NA	NA
WP_081805736.1\|3003084_3003759_+	hypothetical protein	NA	NA	NA	NA
WP_021141234.1\|3003702_3004929_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	O80301	Enterobacteria_phage	7.7e-154	78.6
WP_021141233.1\|3004986_3005391_+\|transposase	IS200/IS605-like element ISAs26 family transposase	A0A1S5RHE3	Helicobacter_phage	8.8e-30	54.8

DBSCAN-SWA_16

3025480 : 3072886

Edwardsiella_phage(25.0%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005328180.1\|3025480_3025963_+\|protease	serine protease inhibitor ecotin	NA	NA	NA	NA
WP_005328181.1\|3026253_3026613_+	DUF413 domain-containing protein	NA	NA	NA	NA
WP_161507370.1\|3026612_3027488_+	HTH-type transcriptional regulator HdfR	NA	NA	NA	NA
WP_161507371.1\|3027554_3028694_-	bifunctional chorismate mutase/prephenate dehydrogenase	NA	NA	NA	NA
WP_139751563.1\|3028812_3029886_-	3-deoxy-7-phosphoheptulonate synthase	A0A0B6VT43	Edwardsiella_phage	7.9e-78	47.9
WP_161507372.1\|3030216_3031296_-	glycerophosphodiester phosphodiesterase	A0A220BY94	Staphylococcus_phage	7.1e-10	26.7
WP_161507373.1\|3031399_3032887_-	glycerol-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_005328190.1\|3033329_3034088_-	DeoR/GlpR family transcriptional regulator	A0A077SK06	Escherichia_phage	2.8e-21	28.2
WP_021141311.1\|3035125_3036262_-\|transposase	ISAs1-like element ISAs12 family transposase	NA	NA	NA	NA
WP_005327692.1\|3037484_3038333_+	aquaporin family protein	NA	NA	NA	NA
WP_041206102.1\|3038362_3039865_+	glycerol kinase GlpK	NA	NA	NA	NA
WP_043130055.1\|3040044_3040947_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_041206103.1\|3041193_3041541_+	GFA family protein	NA	NA	NA	NA
WP_139750857.1\|3041769_3042156_+	hypothetical protein	NA	NA	NA	NA
WP_041206104.1\|3042202_3042568_+	VOC family protein	NA	NA	NA	NA
WP_161507374.1\|3042742_3043033_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_041206106.1\|3043120_3043924_+	2,5-didehydrogluconate reductase DkgB	A0A1V0SDE7	Indivirus	9.6e-36	33.3
WP_005327701.1\|3044297_3045470_+	MFS transporter	NA	NA	NA	NA
WP_005310033.1\|3045533_3045647_-	cytochrome bd-I oxidase subunit CydX	NA	NA	NA	NA
WP_005327704.1\|3045671_3046799_-	cytochrome d ubiquinol oxidase subunit II	NA	NA	NA	NA
WP_041206107.1\|3046798_3048370_-	cytochrome d terminal oxidase subunit I	NA	NA	NA	NA
WP_011191341.1\|3048470_3049745_+\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA
WP_005327708.1\|3049890_3051306_+	PLP-dependent aminotransferase family protein	NA	NA	NA	NA
WP_005327710.1\|3051426_3052233_+	solute-binding protein	NA	NA	NA	NA
WP_005327713.1\|3052286_3052706_+	lipoprotein	NA	NA	NA	NA
WP_005327716.1\|3052713_3053241_+	RNA polymerase sigma factor	NA	NA	NA	NA
WP_041206108.1\|3053225_3053930_+	hypothetical protein	NA	NA	NA	NA
WP_041205828.1\|3054007_3055345_-\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_005332697.1\|3055463_3055922_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_005332699.1\|3056103_3056757_-	tellurite resistance TerB family protein	NA	NA	NA	NA
WP_041207030.1\|3057981_3058452_+	acyl-CoA thioesterase	NA	NA	NA	NA
WP_081805738.1\|3058537_3058693_+	pleiotropic regulatory protein RsmS	NA	NA	NA	NA
WP_005332701.1\|3058762_3059230_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_005332702.1\|3059301_3060153_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_041206109.1\|3060274_3060778_+	nucleoside deaminase	NA	NA	NA	NA
WP_161507375.1\|3060770_3062009_+	CynX/NimT family MFS transporter	NA	NA	NA	NA
WP_005332706.1\|3062052_3063066_-	23S rRNA pseudouridine(2604) synthase RluF	NA	NA	NA	NA
WP_005332707.1\|3063599_3064958_+	NADP-specific glutamate dehydrogenase	NA	NA	NA	NA
WP_005332708.1\|3065143_3065347_+	DUF3955 domain-containing protein	NA	NA	NA	NA
WP_005332709.1\|3065372_3065741_-	VOC family protein	NA	NA	NA	NA
WP_005332710.1\|3065855_3066323_-	hypothetical protein	NA	NA	NA	NA
WP_010676219.1\|3067315_3068413_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_161507376.1\|3068460_3069663_+\|transposase	transposase	NA	NA	NA	NA
WP_011191341.1\|3071611_3072886_+\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA

DBSCAN-SWA_17

3084594 : 3135482

Enterobacteria_phage(10.0%)

integrase,protease,transposase

attL 3128778:3128795|attR 3142273:3142290

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_021141234.1\|3084594_3085821_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	O80301	Enterobacteria_phage	7.7e-154	78.6
WP_041205449.1\|3085878_3086283_+\|transposase	IS200/IS605-like element ISAs26 family transposase	A0A1S5RHE3	Helicobacter_phage	1.1e-29	54.8
WP_005325486.1\|3087596_3088334_-	hypothetical protein	NA	NA	NA	NA
WP_005325488.1\|3088333_3088894_-	hypothetical protein	NA	NA	NA	NA
WP_005325490.1\|3089004_3089907_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_005325492.1\|3089908_3090322_-	hypothetical protein	NA	NA	NA	NA
WP_041206120.1\|3090388_3092119_+	formate--tetrahydrofolate ligase	NA	NA	NA	NA
WP_004575061.1\|3092172_3093510_-\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_005325496.1\|3093632_3095282_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	4.9e-26	45.4
WP_005325498.1\|3095551_3096208_-	GTP cyclohydrolase I FolE	Q6WI31	Vibrio_phage	8.0e-57	54.8
WP_041207032.1\|3096566_3097793_+	molybdopterin molybdotransferase MoeA	NA	NA	NA	NA
WP_005325501.1\|3097789_3098545_+	molybdopterin-synthase adenylyltransferase MoeB	A0A291ATS8	Pandoravirus	1.0e-07	32.3
WP_041206121.1\|3098610_3099390_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_005325503.1\|3099460_3100516_-	molybdenum ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	5.1e-21	35.2
WP_005325504.1\|3100512_3101193_-	molybdate ABC transporter permease subunit	NA	NA	NA	NA
WP_005325505.1\|3101302_3102031_-	molybdate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_005325506.1\|3102115_3102601_-	molybdopterin synthase catalytic subunit MoaE	NA	NA	NA	NA
WP_005325507.1\|3102800_3103046_-	molybdopterin synthase sulfur carrier subunit	NA	NA	NA	NA
WP_005325509.1\|3103042_3103537_-	cyclic pyranopterin monophosphate synthase MoaC	NA	NA	NA	NA
WP_041207033.1\|3103618_3104146_-	molybdenum cofactor biosynthesis protein B	NA	NA	NA	NA
WP_005325513.1\|3104367_3104958_-	cytochrome c3 family protein	NA	NA	NA	NA
WP_041206124.1\|3104969_3105425_-	nitrate reductase cytochrome c-type subunit	NA	NA	NA	NA
WP_041206126.1\|3105424_3106300_-	quinol dehydrogenase ferredoxin subunit NapH	NA	NA	NA	NA
WP_005325518.1\|3106296_3107031_-	ferredoxin-type protein NapG	NA	NA	NA	NA
WP_041206127.1\|3107044_3109534_-	nitrate reductase catalytic subunit NapA	NA	NA	NA	NA
WP_041204444.1\|3109660_3109927_-	chaperone NapD	NA	NA	NA	NA
WP_041206129.1\|3109959_3110469_-	ferredoxin-type protein NapF	NA	NA	NA	NA
WP_005325528.1\|3110719_3111715_-	GTP 3',8-cyclase MoaA	NA	NA	NA	NA
WP_005325535.1\|3111921_3113634_+	nitrate/nitrite two-component system sensor histidine kinase NarQ	NA	NA	NA	NA
WP_005325544.1\|3113633_3114272_+	two-component system response regulator NarL	NA	NA	NA	NA
WP_041206130.1\|3114441_3114867_+	globin	NA	NA	NA	NA
WP_041206132.1\|3115180_3115756_+\|protease	ATP-dependent protease	NA	NA	NA	NA
WP_005325547.1\|3116023_3118105_-	response regulator	A0A1V0SGX0	Hokovirus	2.2e-44	34.4
WP_005325548.1\|3118123_3119308_-	hypothetical protein	NA	NA	NA	NA
WP_005325549.1\|3119419_3120343_+	uridine diphosphate-N-acetylglucosamine-binding protein YvcK	A1IMD5	Streptococcus_phage	9.0e-30	32.3
WP_005325550.1\|3120357_3120693_-	Hpt domain-containing protein	NA	NA	NA	NA
WP_005325551.1\|3120989_3121787_-	class II glutamine amidotransferase	NA	NA	NA	NA
WP_005325554.1\|3121904_3122483_-	D-sedoheptulose 7-phosphate isomerase	A0A067XQR2	Caulobacter_phage	8.2e-13	31.5
WP_041206134.1\|3122742_3125199_+	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_005325558.1\|3125372_3126890_+	DUF3369 domain-containing protein	NA	NA	NA	NA
WP_005325560.1\|3126970_3128227_-	TIGR03503 family protein	NA	NA	NA	NA
WP_161507377.1\|3128223_3128946_-	DNA polymerase III subunit epsilon	A0A1X9SH08	Bradyrhizobium_phage	1.3e-39	40.3
3128778:3128795	attL	NA	NA	NA	NA
WP_161507378.1\|3129082_3130348_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_161507814.1\|3130306_3131578_-\|transposase	transposase	NA	NA	NA	NA
WP_161507379.1\|3131751_3133413_+	hypothetical protein	NA	NA	NA	NA
WP_161507380.1\|3133409_3135482_+\|integrase	integrase	NA	NA	NA	NA
3142273:3142290	attR	NA	NA	NA	NA

DBSCAN-SWA_18

3314139 : 3376191

Bacillus_phage(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_021141311.1\|3314139_3315276_-\|transposase	ISAs1-like element ISAs12 family transposase	NA	NA	NA	NA
WP_161507394.1\|3316316_3319754_+	response regulator	W8CYM9	Bacillus_phage	1.9e-19	43.7
WP_161507395.1\|3320042_3320837_-	hypothetical protein	NA	NA	NA	NA
WP_139751376.1\|3321396_3322281_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_139751375.1\|3322486_3323623_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_042650524.1\|3323820_3324171_+	cyclophilin	NA	NA	NA	NA
WP_139751374.1\|3324201_3325395_+	MFS transporter	NA	NA	NA	NA
WP_041206196.1\|3326834_3327152_-	c-type cytochrome	NA	NA	NA	NA
WP_041206197.1\|3327288_3327438_-	twin-arginine translocase TatA/TatE family subunit	NA	NA	NA	NA
WP_161507396.1\|3327487_3328033_-	NosL protein	NA	NA	NA	NA
WP_005324386.1\|3328057_3328888_-	ABC transporter permease	NA	NA	NA	NA
WP_139751372.1\|3328884_3329811_-	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	2.2e-28	35.8
WP_161507397.1\|3329807_3331127_-	nitrous oxide reductase family maturation protein NosD	NA	NA	NA	NA
WP_021141192.1\|3331186_3333094_-	nitrous-oxide reductase	NA	NA	NA	NA
WP_161507859.1\|3333158_3335327_-	regulatory protein NosR	NA	NA	NA	NA
WP_041204923.1\|3335545_3336688_+\|transposase	IS4-like element ISAs18 family transposase	NA	NA	NA	NA
WP_161507398.1\|3336886_3337396_+	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
WP_005326992.1\|3337998_3338916_+	L,D-transpeptidase family protein	NA	NA	NA	NA
WP_161507399.1\|3338937_3339936_+	DUF481 domain-containing protein	NA	NA	NA	NA
WP_042650508.1\|3339996_3340719_-	MaoC family dehydratase	NA	NA	NA	NA
WP_161507400.1\|3340966_3341908_-	23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF	NA	NA	NA	NA
WP_041206201.1\|3342060_3342549_-	peptidase P60	A0A217EQL1	Bacillus_phage	5.1e-16	42.1
WP_161507401.1\|3342825_3343548_+	4'-phosphopantetheinyl transferase superfamily protein	NA	NA	NA	NA
WP_043131180.1\|3343544_3344393_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_025327798.1\|3344526_3344769_-	lipoprotein	NA	NA	NA	NA
WP_041206202.1\|3344992_3345646_-	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2I2L4Y7	Orpheovirus	4.6e-36	43.0
WP_042650512.1\|3346107_3346944_+	formyltetrahydrofolate deformylase	M4QRX9	Synechococcus_phage	1.4e-13	38.2
WP_161507402.1\|3347008_3348277_-	YdgA family protein	NA	NA	NA	NA
WP_005326968.1\|3348384_3349866_-	cardiolipin synthase	NA	NA	NA	NA
WP_161507403.1\|3349962_3350514_+	DUF1439 domain-containing protein	NA	NA	NA	NA
WP_161507404.1\|3350504_3350963_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_161507860.1\|3351272_3352007_+	lytic transglycosylase domain-containing protein	A0A0H3V0Q1	Geobacillus_virus	8.8e-28	57.7
WP_161507405.1\|3352128_3352815_-	aquaporin Z	NA	NA	NA	NA
WP_005326958.1\|3353127_3353649_-	crossover junction endodeoxyribonuclease RuvC	NA	NA	NA	NA
WP_161507406.1\|3353913_3354828_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_161507407.1\|3354999_3355503_+	damage-inducible protein DinB	NA	NA	NA	NA
WP_161507408.1\|3355533_3355761_-	hypothetical protein	NA	NA	NA	NA
WP_019706001.1\|3356258_3357206_+\|transposase	IS30-like element ISAs2 family transposase	Q9MBM9	Staphylococcus_prophage	1.4e-41	35.7
WP_161507409.1\|3357351_3359745_-	YgiQ family radical SAM protein	M1QSD9	Pseudomonas_phage	2.5e-100	68.5
WP_161507410.1\|3359891_3363038_-	efflux RND transporter permease subunit	S5VTK5	Leptospira_phage	1.3e-75	23.6
WP_161507411.1\|3363037_3364102_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_161507412.1\|3364300_3365857_+	diguanylate cyclase	A0A127AWB9	Bacillus_phage	1.5e-21	37.9
WP_005333067.1\|3365890_3366754_+	patatin	NA	NA	NA	NA
WP_042648643.1\|3366823_3368185_-	sodium-dependent transporter	NA	NA	NA	NA
WP_005298604.1\|3368380_3368647_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_042648642.1\|3368905_3369499_+	hypothetical protein	NA	NA	NA	NA
WP_041206213.1\|3369807_3370827_+	porin OmpA	NA	NA	NA	NA
WP_011191341.1\|3371306_3372581_-\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA
WP_161507413.1\|3372679_3373645_+	OmpA family protein	NA	NA	NA	NA
WP_084865641.1\|3373695_3374898_-\|transposase	ISL3-like element ISAeme19 family transposase	A9YX10	Burkholderia_phage	1.4e-102	53.2
WP_161507819.1\|3374976_3376191_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	8.7e-49	49.5

DBSCAN-SWA_19

3499880 : 3549170

Bacillus_phage(28.57%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_021141311.1\|3499880_3501017_+\|transposase	ISAs1-like element ISAs12 family transposase	NA	NA	NA	NA
WP_005330785.1\|3501162_3501603_-	flavodoxin	NA	NA	NA	NA
WP_041206262.1\|3501788_3502535_-\|tRNA	tRNA pseudouridine(65) synthase TruC	NA	NA	NA	NA
WP_025327927.1\|3502605_3502941_-	YqcC family protein	NA	NA	NA	NA
WP_005330776.1\|3503152_3504181_+	DUF3549 family protein	NA	NA	NA	NA
WP_041206263.1\|3504252_3504549_+	DUF3301 domain-containing protein	NA	NA	NA	NA
WP_005330771.1\|3504615_3504852_+	DUF2789 domain-containing protein	NA	NA	NA	NA
WP_041207059.1\|3505044_3505341_+	hypothetical protein	NA	NA	NA	NA
WP_005330766.1\|3505350_3506136_+	Zn-ribbon-containing protein	NA	NA	NA	NA
WP_041206264.1\|3506228_3506777_-	SecY-interacting protein	NA	NA	NA	NA
WP_041206265.1\|3506882_3507731_+	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	A0A126HGP3	Vibrio_phage	1.6e-41	36.7
WP_005330744.1\|3507845_3510116_+	hypothetical protein	NA	NA	NA	NA
WP_005330743.1\|3510201_3511797_+	diguanylate cyclase	A0A127AWB9	Bacillus_phage	4.3e-19	36.6
WP_041206266.1\|3511955_3513311_+	LOG family protein	NA	NA	NA	NA
WP_005330737.1\|3513443_3514253_+	flap endonuclease Xni	U5PWU8	Bacillus_phage	1.2e-14	29.1
WP_005330735.1\|3514395_3515403_+	isocitrate dehydrogenase	NA	NA	NA	NA
WP_005330733.1\|3515522_3515966_+	hypothetical protein	NA	NA	NA	NA
WP_041206267.1\|3516048_3517143_-	23S rRNA (cytidine(2498)-2'-O)-methyltransferase RlmM	NA	NA	NA	NA
WP_041206268.1\|3517135_3517522_-	DUF423 domain-containing protein	NA	NA	NA	NA
WP_005330730.1\|3517556_3518195_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_025327944.1\|3518199_3519120_-	transcriptional regulator GcvA	NA	NA	NA	NA
WP_041204928.1\|3520082_3521210_+\|transposase	ISAs1-like element ISKpn9 family transposase	NA	NA	NA	NA
WP_005330722.1\|3522898_3523951_-	DNA polymerase IV	NA	NA	NA	NA
WP_005330720.1\|3524152_3524365_+	hypothetical protein	NA	NA	NA	NA
WP_005330718.1\|3524438_3524663_-	(Na+)-NQR maturation NqrM	NA	NA	NA	NA
WP_111909910.1\|3524765_3525809_-	FAD:protein FMN transferase ApbE	NA	NA	NA	NA
WP_103244418.1\|3525812_3527036_-	NADH:ubiquinone reductase (Na(+)-transporting) subunit F	NA	NA	NA	NA
WP_005330713.1\|3527053_3527650_-	NADH:ubiquinone reductase (Na(+)-transporting) subunit E	NA	NA	NA	NA
WP_005330711.1\|3527653_3528286_-	NADH:ubiquinone reductase (Na(+)-transporting) subunit D	NA	NA	NA	NA
WP_025327949.1\|3528278_3529067_-	Na(+)-translocating NADH-quinone reductase subunit C	NA	NA	NA	NA
WP_005330707.1\|3529056_3530286_-	NADH:ubiquinone reductase (Na(+)-transporting) subunit B	NA	NA	NA	NA
WP_161507458.1\|3530289_3531633_-	Na(+)-translocating NADH-quinone reductase subunit A	NA	NA	NA	NA
WP_041204526.1\|3532072_3532381_-	BolA/IbaG family iron-sulfur metabolism protein	NA	NA	NA	NA
WP_041206273.1\|3532600_3533734_+	methyltransferase	NA	NA	NA	NA
WP_042649552.1\|3533746_3534319_+	lipoprotein	NA	NA	NA	NA
WP_161507459.1\|3534334_3534886_+	peptidyl-prolyl cis-trans isomerase	A0A076FI46	Aureococcus_anophage	2.0e-08	30.9
WP_161507460.1\|3535001_3535331_+	hypothetical protein	NA	NA	NA	NA
WP_161507461.1\|3535416_3536820_+	AmpG family muropeptide MFS transporter	NA	NA	NA	NA
WP_139751339.1\|3536976_3537819_+	hypothetical protein	NA	NA	NA	NA
WP_041206278.1\|3537922_3538405_-	YajQ family cyclic di-GMP-binding protein	NA	NA	NA	NA
WP_161507462.1\|3538619_3539567_+	2-dehydropantoate 2-reductase	NA	NA	NA	NA
WP_161507463.1\|3539603_3540164_+	DJ-1 family protein	NA	NA	NA	NA
WP_161506736.1\|3540732_3541488_-	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	6.8e-60	51.9
WP_041206683.1\|3541502_3543044_-\|transposase	IS21 family transposase	K4I413	Acidithiobacillus_phage	3.2e-128	47.2
WP_161507464.1\|3543902_3545106_+\|transposase	IS3 family transposase	Q9ZXG3	Shigella_phage	2.0e-114	70.5
WP_041204923.1\|3545169_3546312_-\|transposase	IS4-like element ISAs18 family transposase	NA	NA	NA	NA
WP_161507465.1\|3546509_3547208_-	DUF2931 family protein	NA	NA	NA	NA
WP_004576012.1\|3547751_3549170_-\|transposase	IS66-like element ISAs21 family transposase	NA	NA	NA	NA

DBSCAN-SWA_20

3592766 : 3663432

Escherichia_phage(28.57%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005323562.1\|3592766_3593684_-\|transposase	IS5 family transposase	A0A1V0E8E1	Vibrio_phage	2.6e-101	59.5
WP_012564931.1\|3593776_3594724_-\|transposase	IS30-like element ISAeca1 family transposase	Q9MBM9	Staphylococcus_prophage	1.0e-44	36.9
WP_019706001.1\|3594810_3595758_-\|transposase	IS30-like element ISAs2 family transposase	Q9MBM9	Staphylococcus_prophage	1.4e-41	35.7
WP_161507864.1\|3595901_3596459_-	hypothetical protein	NA	NA	NA	NA
WP_161507490.1\|3596863_3597826_-	family 43 glycosylhydrolase	NA	NA	NA	NA
WP_005328684.1\|3597942_3599043_-	sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC	G9BWD6	Planktothrix_phage	4.7e-25	35.2
WP_041206300.1\|3599115_3599943_-	carbohydrate ABC transporter permease	NA	NA	NA	NA
WP_050504416.1\|3599944_3600835_-	sugar ABC transporter permease	NA	NA	NA	NA
WP_005328673.1\|3600901_3602185_-	extracellular solute-binding protein	NA	NA	NA	NA
WP_161507491.1\|3602251_3603328_-	cellulase family glycosylhydrolase	NA	NA	NA	NA
WP_161507492.1\|3603630_3603798_+	LacI family transcriptional regulator	NA	NA	NA	NA
WP_161507865.1\|3603842_3604166_+	substrate-binding domain-containing protein	NA	NA	NA	NA
WP_161507493.1\|3604162_3605032_+	polyphosphate kinase 2	NA	NA	NA	NA
WP_081934583.1\|3605305_3606946_-	SulP family inorganic anion transporter	NA	NA	NA	NA
WP_042649267.1\|3607195_3608257_+	PQQ-dependent sugar dehydrogenase	NA	NA	NA	NA
WP_005328663.1\|3608273_3608429_+	entericidin A/B family lipoprotein	NA	NA	NA	NA
WP_005328660.1\|3608448_3609237_-	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	2.1e-64	52.0
WP_042649266.1\|3609492_3610401_+	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	2.6e-106	70.9
WP_161507494.1\|3610397_3611651_+	four-carbon acid sugar kinase family protein	A0A077SLJ7	Escherichia_phage	6.3e-127	60.4
WP_005328654.1\|3611643_3612276_+	aldolase	A0A077SK32	Escherichia_phage	1.5e-76	68.4
WP_161507495.1\|3612337_3613111_+	hydroxypyruvate isomerase family protein	NA	NA	NA	NA
WP_042650707.1\|3613151_3614102_+	SDR family oxidoreductase	Q76TT0	Molluscum_contagiosum_virus	5.9e-08	27.8
WP_005328642.1\|3614098_3615604_+	gluconate permease	NA	NA	NA	NA
WP_161507496.1\|3615689_3616580_+	DMT family transporter	NA	NA	NA	NA
WP_042649124.1\|3616639_3618571_+	HAMP domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	3.6e-12	32.8
WP_161507497.1\|3619184_3620585_+	OprD family porin	NA	NA	NA	NA
WP_042649126.1\|3620700_3621531_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_042649127.1\|3621647_3621980_-	DUF1904 family protein	NA	NA	NA	NA
WP_161507498.1\|3622050_3622932_+	TraB/GumN family protein	NA	NA	NA	NA
WP_081805766.1\|3623099_3623249_+	DUF3149 domain-containing protein	NA	NA	NA	NA
WP_042649129.1\|3623359_3623941_+	DNA endonuclease SmrA	NA	NA	NA	NA
WP_042649130.1\|3624047_3625526_+	carboxypeptidase M32	NA	NA	NA	NA
WP_042649131.1\|3625676_3627197_+	DNA-3-methyladenine glycosylase 2 family protein	NA	NA	NA	NA
WP_042649132.1\|3627193_3627670_+	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	9.7e-20	57.1
WP_041206310.1\|3628016_3628391_+	cupin	NA	NA	NA	NA
WP_042649133.1\|3628580_3628838_-	DUF1272 domain-containing protein	NA	NA	NA	NA
WP_042649134.1\|3628884_3629214_-	hypothetical protein	NA	NA	NA	NA
WP_042649135.1\|3629337_3631185_-	U32 family peptidase	Q6DW11	Phage_TP	2.5e-15	41.4
WP_042649136.1\|3631429_3632041_-	LysE family translocator	NA	NA	NA	NA
WP_042649137.1\|3632169_3633123_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_042649138.1\|3633327_3634416_+	ketoacyl-ACP synthase III	NA	NA	NA	NA
WP_042649139.1\|3635113_3635389_+	hypothetical protein	NA	NA	NA	NA
WP_161507499.1\|3635576_3636314_+	EAL domain-containing protein	NA	NA	NA	NA
WP_042649141.1\|3636780_3638142_+	succinyl-CoA synthetase subunit alpha	NA	NA	NA	NA
WP_042649142.1\|3638198_3641306_-	tetrathionate reductase subunit TtrA	NA	NA	NA	NA
WP_042649143.1\|3641305_3642412_-	polysulfide reductase NrfD	NA	NA	NA	NA
WP_042649144.1\|3642401_3643190_-	4Fe-4S dicluster domain-containing protein	NA	NA	NA	NA
WP_161507866.1\|3643450_3645400_+	sensor histidine kinase	NA	NA	NA	NA
WP_139750961.1\|3645396_3646008_+	response regulator	NA	NA	NA	NA
WP_042648531.1\|3646147_3646888_+	dipeptidase PepE	NA	NA	NA	NA
WP_042648532.1\|3646990_3648382_+	class II fumarate hydratase	NA	NA	NA	NA
WP_161507500.1\|3648784_3649222_-	VOC family protein	NA	NA	NA	NA
WP_107961366.1\|3653105_3654251_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_041205253.1\|3654995_3656333_-\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_161507501.1\|3656638_3657712_-	alanine racemase	A0A0P0YM39	Yellowstone_lake_mimivirus	4.3e-23	26.9
WP_005330482.1\|3658008_3659403_-	replicative DNA helicase	A0A1B0VG30	Salmonella_phage	8.5e-181	71.5
WP_005330485.1\|3659829_3660684_+	Tim44 domain-containing protein	NA	NA	NA	NA
WP_004576012.1\|3662013_3663432_+\|transposase	IS66-like element ISAs21 family transposase	NA	NA	NA	NA

DBSCAN-SWA_21

3694795 : 3757903

Vibrio_phage(14.29%)

tRNA,protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005323562.1\|3694795_3695713_-\|transposase	IS5 family transposase	A0A1V0E8E1	Vibrio_phage	2.6e-101	59.5
WP_041206321.1\|3697105_3698080_+	ChaN family lipoprotein	NA	NA	NA	NA
WP_005329152.1\|3698105_3698660_+	cysteine hydrolase	NA	NA	NA	NA
WP_025328092.1\|3698699_3699104_+	hypothetical protein	NA	NA	NA	NA
WP_005329149.1\|3699174_3699732_-	heme utilization protein HutZ	NA	NA	NA	NA
WP_005329147.1\|3699728_3700241_-	heme utilization cystosolic carrier protein HutX	NA	NA	NA	NA
WP_005329145.1\|3700409_3701249_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_005329142.1\|3701245_3702277_+	iron ABC transporter permease	NA	NA	NA	NA
WP_041206322.1\|3702292_3703093_+	heme ABC transporter ATP-binding protein	A0A285PWH2	Cedratvirus	2.3e-13	26.7
WP_005329125.1\|3703342_3703951_-	YitT family protein	NA	NA	NA	NA
WP_041206324.1\|3704254_3705616_+	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	3.3e-81	38.0
WP_005329119.1\|3705612_3706611_+	NAD-dependent epimerase	A0A1V0SKV4	Klosneuvirus	5.7e-30	30.8
WP_041206327.1\|3706694_3708383_-	glycosyltransferase family 39 protein	NA	NA	NA	NA
WP_041206328.1\|3708372_3708738_-	membrane protein	NA	NA	NA	NA
WP_005329116.1\|3708826_3709567_-	glycosyltransferase family 2 protein	V9QJB1	Oenococcus_phage	1.5e-06	26.5
WP_139751352.1\|3709915_3710764_+	transglycosylase SLT domain-containing protein	A0A0H3V0Q1	Geobacillus_virus	9.2e-21	44.1
WP_005329110.1\|3711095_3712763_+	energy-dependent translational throttle protein EttA	A0A2K9L3Z8	Tupanvirus	3.9e-39	28.0
WP_005329107.1\|3713031_3713367_+	hypothetical protein	NA	NA	NA	NA
WP_041206332.1\|3713628_3714984_+	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	7.9e-67	38.0
WP_005327208.1\|3715051_3715870_-	co-chaperone DjlA	NA	NA	NA	NA
WP_041206335.1\|3715889_3716558_-	nucleotidyltransferase family protein	NA	NA	NA	NA
WP_041206336.1\|3716554_3717583_-	phosphotransferase	NA	NA	NA	NA
WP_005327225.1\|3717757_3720190_+	LPS assembly protein LptD	NA	NA	NA	NA
WP_005327228.1\|3720220_3721513_+	peptidylprolyl isomerase SurA	NA	NA	NA	NA
WP_041207076.1\|3721527_3722523_+	4-hydroxythreonine-4-phosphate dehydrogenase PdxA	NA	NA	NA	NA
WP_041206338.1\|3722512_3723340_+	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	NA	NA	NA	NA
WP_041206340.1\|3723344_3723707_+	Co2+/Mg2+ efflux protein ApaG	NA	NA	NA	NA
WP_005327236.1\|3723713_3724535_+	symmetrical bis(5'-nucleosyl)-tetraphosphatase	A0A2R4ALP3	Aeromonas_phage	6.2e-06	42.5
WP_004575061.1\|3724798_3726136_-\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_161507503.1\|3726201_3726528_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_041206342.1\|3726698_3727688_-	luciferase-like monooxygenase	NA	NA	NA	NA
WP_041206344.1\|3727919_3730805_+	HD domain-containing protein	NA	NA	NA	NA
WP_041206346.1\|3730874_3732245_-	YjiH family protein	NA	NA	NA	NA
WP_005327243.1\|3732613_3733819_-	Obg family GTPase CgtA	NA	NA	NA	NA
WP_005911261.1\|3734008_3734266_-	50S ribosomal protein L27	NA	NA	NA	NA
WP_005304210.1\|3734283_3734595_-	50S ribosomal protein L21	NA	NA	NA	NA
WP_161507504.1\|3734837_3735809_+	octaprenyl diphosphate synthase	A0A1V0SE37	Indivirus	3.3e-06	23.3
WP_005327246.1\|3735901_3736090_-	DUF2065 domain-containing protein	NA	NA	NA	NA
WP_041206348.1\|3736175_3737060_-\|protease	protease modulator HflC	NA	NA	NA	NA
WP_041206349.1\|3737063_3738212_-\|protease	FtsH protease activity modulator HflK	NA	NA	NA	NA
WP_005327255.1\|3738294_3739581_-	GTPase HflX	NA	NA	NA	NA
WP_011704864.1\|3739644_3739908_-	RNA chaperone Hfq	NA	NA	NA	NA
WP_081805770.1\|3739980_3740913_-\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_005327259.1\|3740994_3742866_-	DNA mismatch repair endonuclease MutL	A0A1B2LRQ5	Wolbachia_phage	4.6e-57	30.6
WP_041206350.1\|3743046_3744582_-	AMIN domain-containing protein	A0A059WLJ5	Vibrio_phage	6.1e-15	30.4
WP_041206351.1\|3744572_3745046_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	NA	NA	NA	NA
WP_041206352.1\|3745063_3746566_-	bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase	NA	NA	NA	NA
WP_005327306.1\|3746698_3747853_+\|tRNA	tRNA epoxyqueuosine(34) reductase QueG	NA	NA	NA	NA
WP_005327307.1\|3747936_3748680_+	ROK family protein	NA	NA	NA	NA
WP_005327308.1\|3748734_3749190_-	hypothetical protein	NA	NA	NA	NA
WP_041206353.1\|3749672_3750716_+	methionine ABC transporter ATP-binding protein MetN	G9BWD6	Planktothrix_phage	4.0e-34	36.9
WP_005327310.1\|3750774_3751428_+	ABC transporter permease	NA	NA	NA	NA
WP_005327312.1\|3751454_3752255_+	MetQ/NlpA family lipoprotein	NA	NA	NA	NA
WP_041205253.1\|3752372_3753710_+\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_005331636.1\|3753795_3754296_+	transcription/translation regulatory transformer protein RfaH	NA	NA	NA	NA
WP_161507505.1\|3754453_3756406_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	1.5e-13	62.4
WP_103244595.1\|3756474_3757903_+\|transposase	IS66-like element ISAeme23 family transposase	NA	NA	NA	NA

DBSCAN-SWA_22

3762812 : 3842393

Bacillus_phage(25.0%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004576012.1\|3762812_3764231_+\|transposase	IS66-like element ISAs21 family transposase	NA	NA	NA	NA
WP_021141311.1\|3764581_3765718_+\|transposase	ISAs1-like element ISAs12 family transposase	NA	NA	NA	NA
WP_012564931.1\|3765923_3766871_+\|transposase	IS30-like element ISAeca1 family transposase	Q9MBM9	Staphylococcus_prophage	1.0e-44	36.9
WP_099993964.1\|3767091_3768108_-\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	2.2e-186	99.4
WP_041204891.1\|3768313_3769450_+\|transposase	ISAs1-like element ISAeme1 family transposase	NA	NA	NA	NA
WP_041205079.1\|3770451_3771960_-	sodium/proline symporter PutP	NA	NA	NA	NA
WP_005328224.1\|3772234_3773161_-	L,D-transpeptidase family protein	NA	NA	NA	NA
WP_005328233.1\|3773339_3774581_-	mechanosensitive ion channel	NA	NA	NA	NA
WP_041205080.1\|3774714_3775914_-	acetate kinase	NA	NA	NA	NA
WP_041205081.1\|3776240_3776711_-	YhcH/YjgK/YiaL family protein	NA	NA	NA	NA
WP_041205083.1\|3777011_3778118_-	acyltransferase	NA	NA	NA	NA
WP_041205084.1\|3778933_3779494_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_005327028.1\|3779843_3781610_+	hemagglutinin	NA	NA	NA	NA
WP_041204928.1\|3782122_3783250_-\|transposase	ISAs1-like element ISKpn9 family transposase	NA	NA	NA	NA
WP_041205087.1\|3784057_3785251_+	multidrug efflux MFS transporter MdtH	NA	NA	NA	NA
WP_148304728.1\|3785453_3791939_-	type I secretion C-terminal target domain-containing protein	NA	NA	NA	NA
WP_004576012.1\|3791830_3793249_-\|transposase	IS66-like element ISAs21 family transposase	NA	NA	NA	NA
WP_005327944.1\|3794998_3796660_-	putative transporter	NA	NA	NA	NA
WP_041205078.1\|3796778_3797414_-	hemolysin III family protein	NA	NA	NA	NA
WP_005327951.1\|3797645_3799178_+	aminotransferase class V-fold PLP-dependent enzyme	NA	NA	NA	NA
WP_005327953.1\|3799312_3799864_+	septation protein A	NA	NA	NA	NA
WP_005327955.1\|3799887_3800184_+	YciI family protein	NA	NA	NA	NA
WP_005327957.1\|3800275_3801031_-	3'(2'),5'-bisphosphate nucleotidase CysQ	NA	NA	NA	NA
WP_005327958.1\|3801196_3801517_+	ComEA family DNA-binding protein	NA	NA	NA	NA
WP_041205077.1\|3801611_3802523_+	UTP--glucose-1-phosphate uridylyltransferase GalU	A0A127AW70	Bacillus_phage	2.0e-61	45.9
WP_041205076.1\|3802736_3804134_+	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	1.4e-79	38.8
WP_005327964.1\|3804206_3805178_-	response regulator	NA	NA	NA	NA
WP_041206814.1\|3805491_3806166_+	hypothetical protein	NA	NA	NA	NA
WP_041205075.1\|3806232_3807087_+	ATP-binding protein	A0A1B1P8D0	Bacillus_phage	6.2e-09	28.4
WP_005327970.1\|3807213_3807849_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_005327972.1\|3807927_3809133_-	ABC transporter permease	NA	NA	NA	NA
WP_005327974.1\|3809129_3810266_-	ABC transporter permease	NA	NA	NA	NA
WP_005327977.1\|3810265_3811270_-	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_041205074.1\|3811343_3812750_-	TolC family protein	NA	NA	NA	NA
WP_041205073.1\|3813042_3814008_+\|tRNA	tRNA dihydrouridine synthase DusB	NA	NA	NA	NA
WP_005309538.1\|3814033_3814330_+	DNA-binding transcriptional regulator Fis	NA	NA	NA	NA
WP_005327991.1\|3814418_3815051_-	LysE family translocator	NA	NA	NA	NA
WP_161507506.1\|3815183_3816815_+\|transposase	IS1634-like element ISAs25 family transposase	NA	NA	NA	NA
WP_161469620.1\|3816753_3817780_-\|transposase	IS630 family transposase	M4M9P8	Vibrio_phage	2.1e-11	67.4
WP_025328177.1\|3823951_3824302_-	iron-sulfur cluster insertion protein ErpA	A0A2H4N7M3	Lake_Baikal_phage	6.7e-26	49.5
WP_041205072.1\|3824391_3825084_-	hypothetical protein	NA	NA	NA	NA
WP_041205071.1\|3825171_3826566_-	H(+)/Cl(-) exchange transporter ClcA	NA	NA	NA	NA
WP_161507507.1\|3826788_3828075_+	glutamate-1-semialdehyde 2,1-aminomutase	NA	NA	NA	NA
WP_005327593.1\|3828285_3829110_+	hypothetical protein	NA	NA	NA	NA
WP_005327590.1\|3829341_3830247_-	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_005327588.1\|3830493_3831210_-	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_041205070.1\|3831419_3831935_+	DUF2937 family protein	NA	NA	NA	NA
WP_041205069.1\|3831989_3832871_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_041205067.1\|3833029_3833422_+	multidrug transporter	NA	NA	NA	NA
WP_005327579.1\|3833409_3833730_+	multidrug transporter	NA	NA	NA	NA
WP_005327577.1\|3833800_3834211_-	VOC family protein	NA	NA	NA	NA
WP_005327576.1\|3834253_3836575_-	penicillin-binding protein 1B	NA	NA	NA	NA
WP_139751514.1\|3836839_3839287_-	ATP-dependent helicase HrpB	A0A0G2Y9F4	Acanthamoeba_polyphaga_mimivirus	2.2e-27	27.8
WP_005327573.1\|3839523_3840069_+	RNA 2',3'-cyclic phosphodiesterase	NA	NA	NA	NA
WP_005327571.1\|3840065_3840803_+	DNA/RNA nuclease SfsA	NA	NA	NA	NA
WP_005329052.1\|3840928_3841378_+	RNA polymerase-binding protein DksA	NA	NA	NA	NA
WP_041206812.1\|3841490_3842393_+\|tRNA	tRNA glutamyl-Q(34) synthetase GluQRS	NA	NA	NA	NA

DBSCAN-SWA_23

3890019 : 3902226

uncultured_Mediterranean_phage(22.22%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_081805626.1\|3890019_3891885_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-34	32.6
WP_005331907.1\|3892098_3893886_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	4.0e-74	41.4
WP_005331908.1\|3893974_3894418_-	GatB/YqeY domain-containing protein	A0A292GL36	Xanthomonas_phage	2.0e-27	48.6
WP_005309452.1\|3894433_3894649_-	30S ribosomal protein S21	NA	NA	NA	NA
WP_005331910.1\|3894828_3895842_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	3.1e-108	58.6
WP_005331913.1\|3895929_3896913_-	RNA polymerase sigma factor RpoS	F4YCU2	Synechococcus_phage	4.9e-34	33.7
WP_161506916.1\|3896946_3897894_-\|transposase	IS481-like element ISAeme21 family transposase	NA	NA	NA	NA
WP_099993964.1\|3898014_3899031_+\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	2.2e-186	99.4
WP_041205045.1\|3899190_3900255_-	LysM peptidoglycan-binding domain-containing protein	A0A0A7NU10	Lactobacillus_phage	4.9e-11	36.2
WP_041205044.1\|3900264_3900846_-	DedA family protein	NA	NA	NA	NA
WP_005332743.1\|3900842_3901460_-	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	2.4e-34	46.4
WP_005332745.1\|3901464_3902226_-	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	3.3e-70	53.4

DBSCAN-SWA_24

4175938 : 4233664

Bacillus_phage(28.57%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_161507590.1\|4175938_4177282_-\|protease	metalloprotease PmbA	NA	NA	NA	NA
WP_025328542.1\|4177393_4177918_+	ribosome-associated protein	NA	NA	NA	NA
WP_161506878.1\|4178057_4179023_+\|transposase	IS1595 family transposase	NA	NA	NA	NA
WP_161507591.1\|4179040_4182124_-	penicillin-binding protein	NA	NA	NA	NA
WP_161469620.1\|4182399_4183425_+\|transposase	IS630 family transposase	M4M9P8	Vibrio_phage	2.1e-11	67.4
WP_025328544.1\|4183444_4183762_-	DUF496 family protein	NA	NA	NA	NA
WP_005327754.1\|4189846_4191043_+	NnrS family protein	NA	NA	NA	NA
WP_005327753.1\|4191046_4191616_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_161507592.1\|4191731_4192883_+	benzoate/H(+) symporter BenE family transporter	NA	NA	NA	NA
WP_161507593.1\|4193030_4194095_+	DUF3103 family protein	NA	NA	NA	NA
WP_025325515.1\|4194215_4194686_-	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_161507594.1\|4194846_4195365_+	protein tyrosine phosphatase	NA	NA	NA	NA
WP_005327747.1\|4195447_4196395_-	homoserine O-succinyltransferase	NA	NA	NA	NA
WP_041204871.1\|4196539_4197778_+	HD-GYP domain-containing protein	NA	NA	NA	NA
WP_005327739.1\|4197805_4198969_+	competence protein CinA	NA	NA	NA	NA
WP_005327731.1\|4198976_4199492_-	membrane protein	A0A127AVX7	Bacillus_phage	4.3e-05	40.9
WP_161507872.1\|4199932_4201561_+	DUF342 domain-containing protein	NA	NA	NA	NA
WP_043130614.1\|4201675_4202485_+	sugar-phosphatase	NA	NA	NA	NA
WP_161507595.1\|4202850_4203621_+	gamma-glutamyl-gamma-aminobutyrate hydrolase family protein	A0A2P9FI75	Pseudomonas_phage	5.8e-06	29.3
WP_005327724.1\|4203617_4204022_-	hypothetical protein	NA	NA	NA	NA
WP_161507596.1\|4204114_4204825_-	HAD-IA family hydrolase	NA	NA	NA	NA
WP_041206763.1\|4204871_4205828_-	tyrosine recombinase XerC	A0A166YH27	Gordonia_phage	6.5e-15	30.4
WP_161507597.1\|4205820_4206501_-	DUF484 family protein	NA	NA	NA	NA
WP_025325502.1\|4206656_4207487_-	diaminopimelate epimerase	NA	NA	NA	NA
WP_161507598.1\|4207583_4208834_-	diaminopimelate decarboxylase	NA	NA	NA	NA
WP_025325500.1\|4208854_4209061_-	hypothetical protein	NA	NA	NA	NA
WP_005330957.1\|4209134_4209449_+	iron donor protein CyaY	NA	NA	NA	NA
WP_042649021.1\|4209463_4210117_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_005330961.1\|4210194_4212714_-	class I adenylate cyclase	NA	NA	NA	NA
WP_041207133.1\|4213036_4213966_+	hydroxymethylbilane synthase	NA	NA	NA	NA
WP_161507873.1\|4214012_4214747_+	uroporphyrinogen-III synthase	NA	NA	NA	NA
WP_161507599.1\|4214743_4215820_+	heme biosynthesis operon protein HemX	NA	NA	NA	NA
WP_005330966.1\|4215830_4216994_+	hypothetical protein	NA	NA	NA	NA
WP_043130633.1\|4217168_4217420_-	hypothetical protein	NA	NA	NA	NA
WP_041206766.1\|4217589_4218600_-	class II fructose-bisphosphatase	NA	NA	NA	NA
WP_161507600.1\|4218818_4219877_+	porin	NA	NA	NA	NA
WP_161507601.1\|4219963_4220443_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_161507602.1\|4220721_4222764_+	TonB-dependent siderophore receptor	NA	NA	NA	NA
WP_161507874.1\|4222829_4223450_+	peptidase	NA	NA	NA	NA
WP_161507603.1\|4223623_4224661_+	acyltransferase family protein	NA	NA	NA	NA
WP_161507604.1\|4224632_4225010_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_161507605.1\|4225131_4225437_+	monooxygenase	NA	NA	NA	NA
WP_161507606.1\|4225444_4225942_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_161507607.1\|4225987_4226602_-	porin family protein	NA	NA	NA	NA
WP_025325483.1\|4226827_4227466_+	exopolysaccharide biosynthesis protein	NA	NA	NA	NA
WP_025325482.1\|4227575_4228466_-	sensor domain-containing diguanylate cyclase	A0A127AWB9	Bacillus_phage	4.9e-17	34.6
WP_012564931.1\|4228929_4229877_-\|transposase	IS30-like element ISAeca1 family transposase	Q9MBM9	Staphylococcus_prophage	1.0e-44	36.9
WP_161507608.1\|4230241_4230829_-	penicillin-binding protein activator LpoB	NA	NA	NA	NA
WP_099369027.1\|4231164_4232181_+\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	4.9e-186	99.1
WP_011191341.1\|4232389_4233664_-\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA

DBSCAN-SWA_25

4538920 : 4656152

100

Vibrio_phage(10.53%)

holin,protease,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_161469620.1\|4538920_4539947_-\|transposase	IS630 family transposase	M4M9P8	Vibrio_phage	2.1e-11	67.4
WP_161507744.1\|4540057_4541323_-	3-deoxy-D-manno-octulosonic acid transferase	NA	NA	NA	NA
WP_161507745.1\|4541324_4542422_-	lipopolysaccharide heptosyltransferase II	NA	NA	NA	NA
WP_161507746.1\|4542635_4543424_+	glycosyltransferase family 2 protein	A0A1C3NFH8	Phage_NCTB	1.7e-05	36.8
WP_161507747.1\|4543482_4544526_-	glycosyltransferase family 9 protein	NA	NA	NA	NA
WP_005323744.1\|4544748_4545231_+	pantetheine-phosphate adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	4.0e-29	45.9
WP_161507882.1\|4545307_4546186_-	DUF535 domain-containing protein	NA	NA	NA	NA
WP_161507748.1\|4546363_4547176_-	bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase	A0A127AWE5	Bacillus_phage	2.3e-21	28.5
WP_042648922.1\|4547203_4547659_-	hypothetical protein	NA	NA	NA	NA
WP_005323752.1\|4547753_4547921_-	50S ribosomal protein L33	NA	NA	NA	NA
WP_005307492.1\|4547932_4548169_-	50S ribosomal protein L28	NA	NA	NA	NA
WP_042648929.1\|4548305_4548980_-	JAB domain-containing protein	NA	NA	NA	NA
WP_041206610.1\|4549127_4550330_+	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	Q9HH70	Methanothermobacter_phage	1.2e-42	34.0
WP_005323758.1\|4550455_4550914_+	dUTP diphosphatase	Q2NP83	Xanthomonas_phage	5.4e-52	65.1
WP_005323760.1\|4550985_4551582_+	nucleoid occlusion factor SlmA	NA	NA	NA	NA
WP_005323762.1\|4551755_4552592_+	mechanosensitive ion channel	NA	NA	NA	NA
WP_005323764.1\|4552722_4552911_-\|holin	holin	NA	NA	NA	NA
WP_161507749.1\|4553329_4554979_+	glucose-6-phosphate isomerase	NA	NA	NA	NA
WP_041205828.1\|4555031_4556369_-\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_161507750.1\|4556572_4558054_-	ketol-acid reductoisomerase	NA	NA	NA	NA
WP_005323770.1\|4558278_4559172_+	HTH-type transcriptional activator IlvY	NA	NA	NA	NA
WP_005323772.1\|4559274_4559466_+	hypothetical protein	NA	NA	NA	NA
WP_161507751.1\|4559557_4562131_+	bifunctional acetate--CoA ligase family protein/GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_161507752.1\|4567842_4568367_-	menaquinone-dependent protoporphyrinogen IX dehydrogenase	NA	NA	NA	NA
WP_043128965.1\|4568374_4569832_-	potassium transporter	NA	NA	NA	NA
WP_161507753.1\|4569868_4570486_-	YigZ family protein	A0A1X9I5T8	Streptococcus_phage	3.2e-23	35.9
WP_161507754.1\|4570485_4571808_-	Xaa-Pro dipeptidase	NA	NA	NA	NA
WP_161507755.1\|4572004_4573942_+	acetoacetate--CoA ligase	NA	NA	NA	NA
WP_161507756.1\|4574146_4576294_+	fatty acid oxidation complex subunit alpha FadB	NA	NA	NA	NA
WP_161507757.1\|4576315_4577479_+	acetyl-CoA C-acyltransferase FadA	NA	NA	NA	NA
WP_005323928.1\|4577762_4578485_+	response regulator transcription factor	NA	NA	NA	NA
WP_043128973.1\|4578555_4580001_+	HAMP domain-containing protein	NA	NA	NA	NA
WP_041206710.1\|4580006_4581263_+	carbohydrate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_005323922.1\|4581308_4581500_-	hypothetical protein	NA	NA	NA	NA
WP_041206709.1\|4581781_4582027_+	sulfurtransferase TusA	A0A140XB86	Dickeya_phage	2.8e-07	72.2
WP_161507758.1\|4582048_4582393_+	RidA family protein	NA	NA	NA	NA
WP_161507759.1\|4582539_4583196_-	OmpA family lipoprotein	NA	NA	NA	NA
WP_005323913.1\|4583361_4583604_-	hypothetical protein	NA	NA	NA	NA
WP_005323912.1\|4583724_4583979_-	hypothetical protein	NA	NA	NA	NA
WP_161507760.1\|4584061_4584334_-	hypothetical protein	NA	NA	NA	NA
WP_043129211.1\|4584378_4584633_-	hypothetical protein	NA	NA	NA	NA
WP_161507761.1\|4584623_4584863_-	hypothetical protein	NA	NA	NA	NA
WP_161507762.1\|4584953_4585523_-	DNA-3-methyladenine glycosylase I	NA	NA	NA	NA
WP_161507763.1\|4585732_4586659_+\|tRNA	glycine--tRNA ligase subunit alpha	NA	NA	NA	NA
WP_161507764.1\|4586668_4588738_+\|tRNA	glycine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_161507765.1\|4588950_4589901_+\|transposase	transposase	NA	NA	NA	NA
WP_161507766.1\|4590230_4590797_-	hypothetical protein	NA	NA	NA	NA
WP_161507767.1\|4591460_4592684_-\|transposase	transposase	NA	NA	NA	NA
WP_161507883.1\|4593228_4594365_-\|transposase	transposase	NA	NA	NA	NA
WP_099368881.1\|4594486_4595503_-\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	2.2e-186	99.4
WP_161507768.1\|4595822_4597034_-	4Fe-4S binding protein	NA	NA	NA	NA
WP_005330036.1\|4597151_4597493_-	DUF1971 domain-containing protein	NA	NA	NA	NA
WP_161507769.1\|4597544_4598711_-	NADH:flavorubredoxin reductase NorW	NA	NA	NA	NA
WP_161507770.1\|4598707_4600189_-	anaerobic nitric oxide reductase flavorubredoxin	NA	NA	NA	NA
WP_161507771.1\|4600360_4601884_+	nitric oxide reductase transcriptional regulator NorR	NA	NA	NA	NA
WP_041205828.1\|4601955_4603293_-\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_005330032.1\|4603414_4604419_-	substrate-binding domain-containing protein	C6ZCU4	Enterobacteria_phage	2.3e-31	32.2
WP_041206698.1\|4604854_4605976_+	branched-chain amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_005330030.1\|4606040_4606967_+	high-affinity branched-chain amino acid ABC transporter permease LivH	NA	NA	NA	NA
WP_161507772.1\|4606963_4608232_+	high-affinity branched-chain amino acid ABC transporter permease LivM	NA	NA	NA	NA
WP_043132444.1\|4608228_4609014_+	ABC transporter ATP-binding protein	A0A285PWH2	Cedratvirus	4.2e-12	26.8
WP_005330014.1\|4609024_4609726_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	1.5e-16	28.2
WP_161507773.1\|4609728_4610574_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_161507884.1\|4610552_4611122_-	LysE family translocator	NA	NA	NA	NA
WP_005330007.1\|4611313_4611637_+	thiosulfate sulfurtransferase GlpE	NA	NA	NA	NA
WP_161507885.1\|4611666_4612500_+\|protease	rhomboid family intramembrane serine protease GlpG	NA	NA	NA	NA
WP_161507886.1\|4612608_4615011_-	lipase	NA	NA	NA	NA
WP_041206692.1\|4615326_4615584_+	accessory factor UbiK family protein	NA	NA	NA	NA
WP_004575061.1\|4615642_4616980_-\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_005328900.1\|4617204_4617903_-	NAD(P)H-flavin reductase	NA	NA	NA	NA
WP_025328827.1\|4618058_4619528_-	4-hydroxy-3-polyprenylbenzoate decarboxylase	NA	NA	NA	NA
WP_161507774.1\|4619561_4620566_-	hypothetical protein	NA	NA	NA	NA
WP_041206691.1\|4620673_4621939_-	transcription termination factor Rho	NA	NA	NA	NA
WP_025328829.1\|4622145_4622472_-	thioredoxin TrxA	A0A1J0GW78	Streptomyces_phage	4.8e-18	42.3
WP_161507775.1\|4622585_4623875_+	ATP-dependent RNA helicase RhlB	A0A1V0SBR7	Catovirus	3.1e-36	26.2
WP_005328890.1\|4623888_4625379_+	guanosine-5'-triphosphate,3'-diphosphate diphosphatase	NA	NA	NA	NA
WP_161507776.1\|4625581_4626568_+	DUF4382 domain-containing protein	NA	NA	NA	NA
WP_005328887.1\|4626598_4626853_+	modulator protein	NA	NA	NA	NA
WP_041207127.1\|4626926_4627679_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_161507777.1\|4627739_4630307_-	EAL domain-containing protein	G3MA91	Bacillus_virus	1.8e-19	31.5
WP_161507778.1\|4630547_4632590_-	oligopeptidase A	A0A1V0SD92	Indivirus	3.5e-34	20.6
WP_161507779.1\|4632811_4633831_-	porphobilinogen synthase	NA	NA	NA	NA
WP_161507780.1\|4633834_4634620_-	hydrolase TatD	NA	NA	NA	NA
WP_005328872.1\|4634731_4635487_-	twin-arginine translocase subunit TatC	NA	NA	NA	NA
WP_161507781.1\|4635483_4635927_-	Sec-independent protein translocase subunit TatB	NA	NA	NA	NA
WP_025328841.1\|4635930_4636179_-	twin-arginine translocase subunit TatA	NA	NA	NA	NA
WP_161507782.1\|4636219_4637860_-	ubiquinone biosynthesis regulatory protein kinase UbiB	G9E4X0	Ostreococcus_lucimarinus_virus	2.0e-35	30.0
WP_161507783.1\|4637859_4638468_-	hypothetical protein	NA	NA	NA	NA
WP_041206685.1\|4638476_4639229_-	bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE	NA	NA	NA	NA
WP_005328863.1\|4639294_4639672_-	fluoride efflux transporter CrcB	A0A2H4J148	uncultured_Caudovirales_phage	4.4e-07	37.2
WP_161507784.1\|4639761_4641027_-	cytosine deaminase	NA	NA	NA	NA
WP_161507785.1\|4641020_4642265_-	cytosine permease	NA	NA	NA	NA
WP_161469620.1\|4642363_4643389_+\|transposase	IS630 family transposase	M4M9P8	Vibrio_phage	2.1e-11	67.4
WP_161507786.1\|4649400_4650579_-	hypothetical protein	NA	NA	NA	NA
WP_161507787.1\|4650581_4651244_-	TonB family protein	NA	NA	NA	NA
WP_005326222.1\|4651240_4651642_-	biopolymer transporter ExbD	NA	NA	NA	NA
WP_025328851.1\|4651638_4652169_-	MotA/TolQ/ExbB proton channel family protein	NA	NA	NA	NA
WP_161507788.1\|4652165_4653461_-	MotA/TolQ/ExbB proton channel family protein	NA	NA	NA	NA
WP_161507789.1\|4653457_4654219_-	DUF3450 domain-containing protein	NA	NA	NA	NA
WP_021141311.1\|4655015_4656152_+\|transposase	ISAs1-like element ISAs12 family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr_ID: NZ_CP047962.1|WP_005331455.1|1594751_1594940_+|hypothetical-protein

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Acr_ID: NZ_CP047962.1|WP_161507158.1|2271073_2271559_+|hypothetical-protein

Click the colored protein region to show detailed information

Acr_ID: NZ_CP047962.1|WP_161507159.1|2271626_2272211_+|hypothetical-protein

Click the colored protein region to show detailed information

Acr_ID: NZ_CP047962.1|WP_041205445.1|2865958_2866456_-|hypothetical-protein

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Acr_ID: NZ_CP047962.1|WP_041205443.1|2866524_2867385_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_CP047962.1|WP_005331455.1|1594751_1594940_+|hypothetical-protein

1594751_1594940_+

62 aa aa

1463824-1664884

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP047962_6	Orphan	6.1\|3595865\|30\|NZ_CP047962\|CRISPRCasFinder	3595865-3595894	30	1621348-1621377	0

1. spacer 6.1|3595865|30|NZ_CP047962|CRISPRCasFinder matches to NZ_CP047962 position: 1621348-1621377, mismatch: 0

accgcctctctcctatgcaccatgggcatt	CRISPR spacer
accgcctctctcctatgcaccatgggcatt	Protospacer
******************************

NZ_CP047962.1|WP_161507158.1|2271073_2271559_+|hypothetical-protein

2271073_2271559_+

161 aa aa

2253172-2389669

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP047962_6	Orphan	6.1\|3595865\|30\|NZ_CP047962\|CRISPRCasFinder	3595865-3595894	30	2270945-2270974	0

1. spacer 6.1|3595865|30|NZ_CP047962|CRISPRCasFinder matches to NZ_CP047962 position: 2270945-2270974, mismatch: 0

accgcctctctcctatgcaccatgggcatt	CRISPR spacer
accgcctctctcctatgcaccatgggcatt	Protospacer
******************************

NZ_CP047962.1|WP_161507159.1|2271626_2272211_+|hypothetical-protein

2271626_2272211_+

194 aa aa

2253172-2389669

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP047962_6	Orphan	6.1\|3595865\|30\|NZ_CP047962\|CRISPRCasFinder	3595865-3595894	30	2270945-2270974	0

1. spacer 6.1|3595865|30|NZ_CP047962|CRISPRCasFinder matches to NZ_CP047962 position: 2270945-2270974, mismatch: 0

accgcctctctcctatgcaccatgggcatt	CRISPR spacer
accgcctctctcctatgcaccatgggcatt	Protospacer
******************************

NZ_CP047962.1|WP_041205445.1|2865958_2866456_-|hypothetical-protein

2865958_2866456_-

165 aa aa

2797309-2934144

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location
NZ_CP047962_6	Orphan	6.1\|3595865\|30\|NZ_CP047962\|CRISPRCasFinder	3595865-3595894	30	2848664-2848693
NZ_CP047962_6	Orphan	6.1\|3595865\|30\|NZ_CP047962\|CRISPRCasFinder	3595865-3595894	30	2863947-2863976
NZ_CP047962_6	Orphan	6.1\|3595865\|30\|NZ_CP047962\|CRISPRCasFinder	3595865-3595894	30	2900198-2900227

1. spacer 6.1|3595865|30|NZ_CP047962|CRISPRCasFinder matches to NZ_CP047962 position: 2848664-2848693, mismatch: 0

accgcctctctcctatgcaccatgggcatt	CRISPR spacer
accgcctctctcctatgcaccatgggcatt	Protospacer
******************************

2. spacer 6.1|3595865|30|NZ_CP047962|CRISPRCasFinder matches to NZ_CP047962 position: 2863947-2863976, mismatch: 0

accgcctctctcctatgcaccatgggcatt	CRISPR spacer
accgcctctctcctatgcaccatgggcatt	Protospacer
******************************

3. spacer 6.1|3595865|30|NZ_CP047962|CRISPRCasFinder matches to NZ_CP047962 position: 2900198-2900227, mismatch: 0

accgcctctctcctatgcaccatgggcatt	CRISPR spacer
accgcctctctcctatgcaccatgggcatt	Protospacer
******************************

NZ_CP047962.1|WP_041205443.1|2866524_2867385_-|hypothetical-protein

2866524_2867385_-

286 aa aa

2797309-2934144

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location
NZ_CP047962_6	Orphan	6.1\|3595865\|30\|NZ_CP047962\|CRISPRCasFinder	3595865-3595894	30	2848664-2848693
NZ_CP047962_6	Orphan	6.1\|3595865\|30\|NZ_CP047962\|CRISPRCasFinder	3595865-3595894	30	2863947-2863976
NZ_CP047962_6	Orphan	6.1\|3595865\|30\|NZ_CP047962\|CRISPRCasFinder	3595865-3595894	30	2900198-2900227

1. spacer 6.1|3595865|30|NZ_CP047962|CRISPRCasFinder matches to NZ_CP047962 position: 2848664-2848693, mismatch: 0

accgcctctctcctatgcaccatgggcatt	CRISPR spacer
accgcctctctcctatgcaccatgggcatt	Protospacer
******************************

2. spacer 6.1|3595865|30|NZ_CP047962|CRISPRCasFinder matches to NZ_CP047962 position: 2863947-2863976, mismatch: 0

accgcctctctcctatgcaccatgggcatt	CRISPR spacer
accgcctctctcctatgcaccatgggcatt	Protospacer
******************************

3. spacer 6.1|3595865|30|NZ_CP047962|CRISPRCasFinder matches to NZ_CP047962 position: 2900198-2900227, mismatch: 0

accgcctctctcctatgcaccatgggcatt	CRISPR spacer
accgcctctctcctatgcaccatgggcatt	Protospacer
******************************