CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP048279	Staphylococcus sp. MI 10-1553 chromosome, complete genome	2 crisprs	cas1,cas2,cas10,csm2gr11,csm3gr7,csm4gr5,csm5gr7,csm6,cas6,cas14j,cas3,DEDDh,RT,DinG,csa3,cas9,WYL	0	9	14	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP048279_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP048279_1

140048-140521

TypeIII

Consensus_repeat	Method
AATCAGATAGAACCCCGTACAAAAGGGGACGAGAACT	PILER-CR
AATCAGATAGAACCCCGTACAAAAGGGGACGAGAACT	CRISPRCasFinder
AATCAGATAGAACCCCGTACAAAAGGGGACGAGAACT	CRT

6 spacers

cas6,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas2,cas1

The CRISPR arrays of NZ_CP048279_1

>merge|NZ_CP048279|1|140048-140521|PILER-CR,CRISPRCasFinder,CRT
AATCAGATAGAACCCCGTACAAAAGGGGACGAGAACATAAAATAACTCCGTCTGCTTCATTAAAATTGTACAATCAGATAGAACCCCGTACAAAAGGGGACGAGAACTAATTATTTTTTTGAATTCTTTATATTTTTTAGAAATCAGATAGAACCCCGTACAAAAGGGGACGAGAACTCAAATTTCACGCTACTAGTTCGCCATATGGTGTTTTAATCAGATAGAACCCCGTACAAAAGGGGACGAGAACTAAACGGTCGTGATTTGATTTCTTTGATGTATTTTTCATAATCAGATAGAACCCCGTACAAAAGGGGACGAGAACTTGTAAACTTCGAGCATTTGTTTATCTGTACTTAACAATCAGATAGAACCCCGTACAAAAGGGGACGAGAACTCGATAGCAAAAGTATTATAAAGTGCATTACGATGATTTGAATCAGATAGAACCCCGTACAAAAGGGGACGAAAGGT

>NZ_CP048279|1|1|140048-140445|PILER-CR
AATCAGATAGAACCCCGTACAAAAGGGGACGAGAACA	TAAAATAACTCCGTCTGCTTCATTAAAATTGTAC
AATCAGATAGAACCCCGTACAAAAGGGGACGAGAACT	AATTATTTTTTTGAATTCTTTATATTTTTTAGA
AATCAGATAGAACCCCGTACAAAAGGGGACGAGAACT	CAAATTTCACGCTACTAGTTCGCCATATGGTGTTTT
AATCAGATAGAACCCCGTACAAAAGGGGACGAGAACT	AAACGGTCGTGATTTGATTTCTTTGATGTATTTTTCAT
AATCAGATAGAACCCCGTACAAAAGGGGACGAGAACT	TGTAAACTTCGAGCATTTGTTTATCTGTACTTAAC
AATCAGATAGAACCCCGTACAAAAGGGGACGAGAACT

>NZ_CP048279|1|1|140048-140521|CRISPRCasFinder
AATCAGATAGAACCCCGTACAAAAGGGGACGAGAACA	TAAAATAACTCCGTCTGCTTCATTAAAATTGTAC
AATCAGATAGAACCCCGTACAAAAGGGGACGAGAACT	AATTATTTTTTTGAATTCTTTATATTTTTTAGA
AATCAGATAGAACCCCGTACAAAAGGGGACGAGAACT	CAAATTTCACGCTACTAGTTCGCCATATGGTGTTTT
AATCAGATAGAACCCCGTACAAAAGGGGACGAGAACT	AAACGGTCGTGATTTGATTTCTTTGATGTATTTTTCAT
AATCAGATAGAACCCCGTACAAAAGGGGACGAGAACT	TGTAAACTTCGAGCATTTGTTTATCTGTACTTAAC
AATCAGATAGAACCCCGTACAAAAGGGGACGAGAACT	CGATAGCAAAAGTATTATAAAGTGCATTACGATGATTTG
AATCAGATAGAACCCCGTACAAAAGGGGACGAAAGGT

>NZ_CP048279|1|1|140048-140521|CRT
AATCAGATAGAACCCCGTACAAAAGGGGACGAGAACA	TAAAATAACTCCGTCTGCTTCATTAAAATTGTAC
AATCAGATAGAACCCCGTACAAAAGGGGACGAGAACT	AATTATTTTTTTGAATTCTTTATATTTTTTAGA
AATCAGATAGAACCCCGTACAAAAGGGGACGAGAACT	CAAATTTCACGCTACTAGTTCGCCATATGGTGTTTT
AATCAGATAGAACCCCGTACAAAAGGGGACGAGAACT	AAACGGTCGTGATTTGATTTCTTTGATGTATTTTTCAT
AATCAGATAGAACCCCGTACAAAAGGGGACGAGAACT	TGTAAACTTCGAGCATTTGTTTATCTGTACTTAAC
AATCAGATAGAACCCCGTACAAAAGGGGACGAGAACT	CGATAGCAAAAGTATTATAAAGTGCATTACGATGATTTG
AATCAGATAGAACCCCGTACAAAAGGGGACGAAAGGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP048279.1\|WP_162680858.1\|142285_142654_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224037
NZ_CP048279.1\|WP_162680862.1\|146908_147982_-\|DUF871-domain-containing-protein	unknown	unknown	gnl\|CDD\|377567
NZ_CP048279.1\|WP_162680848.1\|130166_130835_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_CP048279.1\|WP_162680851.1\|132473_134747_+\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	cd09680_cas10_CAS-III	gnl\|CDD\|187811
NZ_CP048279.1\|WP_162680861.1\|146025_146922_-\|N-acetylmuramic-acid-6-phosphate-etherase	unknown	unknown	gnl\|CDD\|235467
NZ_CP048279.1\|WP_162680854.1\|135831_136740_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	COG1567_csm4gr5_CAS-III-A	gnl\|CDD\|273866
NZ_CP048279.1\|WP_162680852.1\|134749_135175_+\|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	cd09647_csm2gr11_CAS-III-A	gnl\|CDD\|187778
NZ_CP048279.1\|WP_162680855.1\|136743_137748_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	cd09662_csm5gr7_CAS-III-A	gnl\|CDD\|187793
NZ_CP048279.1\|WP_162680866.1\|158240_158441_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048279.1\|WP_162680867.1\|158610_161406_+\|type-I-restriction-endonuclease-subunit-R	unknown	unknown	gnl\|CDD\|223683
NZ_CP048279.1\|WP_162680860.1\|144038_146009_-\|PTS-transporter-subunit-EIIC	unknown	unknown	gnl\|CDD\|273919
NZ_CP048279.1\|WP_162680865.1\|157044_157872_+\|autolysin	unknown	unknown	gnl\|CDD\|214760
NZ_CP048279.1\|WP_162680856.1\|137764_139033_+\|type-III-A-CRISPR-associated-protein-Csm6	csm6	cd09699_csm6_CAS-III-A	gnl\|CDD\|131720
NZ_CP048279.1\|WP_162680864.1\|156002_156662_+\|4'-phosphopantetheinyl-transferase-superfamily-protein	unknown	unknown	gnl\|CDD\|225002
NZ_CP048279.1\|WP_162680857.1\|139029_139782_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl\|CDD\|227838
NZ_CP048279.1\|WP_162680859.1\|143085_143937_+\|MurR/RpiR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224651
NZ_CP048279.1\|WP_162680849.1\|131246_132155_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694
NZ_CP048279.1\|WP_162680850.1\|132154_132460_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09638_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|273699
NZ_CP048279.1\|WP_162680863.1\|148864_155992_+\|amino-acid-adenylation-domain-containing-protein	unknown	unknown	gnl\|CDD\|237108
NZ_CP048279.1\|WP_162680853.1\|135176_135821_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187815

Protein	Function_ID	Function_description	E-value
NZ_CP048279.1\|WP_162680858.1\|142285_142654_+\|hypothetical-protein	gnl\|CDD\|224037	COG1112, COG1112, Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair].	0.000103941
NZ_CP048279.1\|WP_162680862.1\|146908_147982_-\|DUF871-domain-containing-protein	gnl\|CDD\|377567	pfam05913, DUF871, Bacterial protein of unknown function (DUF871). This family consists of several conserved hypothetical proteins from bacteria and archaea. The function of this family is unknown.	3.69763e-150
NZ_CP048279.1\|WP_162680848.1\|130166_130835_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	2.73074e-64
NZ_CP048279.1\|WP_162680851.1\|132473_134747_+\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	gnl\|CDD\|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	0
NZ_CP048279.1\|WP_162680861.1\|146025_146922_-\|N-acetylmuramic-acid-6-phosphate-etherase	gnl\|CDD\|235467	PRK05441, murQ, N-acetylmuramic acid-6-phosphate etherase; Reviewed.	1.05913e-171
NZ_CP048279.1\|WP_162680854.1\|135831_136740_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	gnl\|CDD\|273866	TIGR01903, Hypothetical_protein., CRISPR type III-A/MTUBE-associated RAMP protein Csm4. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. Members of this cas gene family are found in the mtube subtype of CRISPR/cas locus and designated Csm4, for CRISPR/cas Subtype Mtube, protein 4.	4.50932e-37
NZ_CP048279.1\|WP_162680852.1\|134749_135175_+\|type-III-A-CRISPR-associated-protein-Csm2	gnl\|CDD\|187778	cd09647, Csm2_III-A, CRISPR/Cas system-associated protein Csm2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; signature gene for subtype III-A.	8.68329e-19
NZ_CP048279.1\|WP_162680855.1\|136743_137748_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	gnl\|CDD\|187793	cd09662, Csm5_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	1.40382e-14
NZ_CP048279.1\|WP_162680867.1\|158610_161406_+\|type-I-restriction-endonuclease-subunit-R	gnl\|CDD\|223683	COG0610, COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms].	0
NZ_CP048279.1\|WP_162680860.1\|144038_146009_-\|PTS-transporter-subunit-EIIC	gnl\|CDD\|273919	TIGR01995, beta-glucosides_PTS_EIIBCA, PTS system, beta-glucoside-specific IIABC component. This model represents a family of PTS enzyme II proteins in which all three domains are found in the same polypeptide chain and which appear to have a broad specificity for beta-glucosides including salicin (beta-D-glucose-1-salicylate) and arbutin (Hydroquinone-O-beta-D-glucopyranoside). These are distinct from the closely related sucrose-specific and trehalose-specific PTS transporters.	5.55799e-119
NZ_CP048279.1\|WP_162680865.1\|157044_157872_+\|autolysin	gnl\|CDD\|214760	smart00644, Ami_2, Ami_2 domain.	3.72793e-14
NZ_CP048279.1\|WP_162680856.1\|137764_139033_+\|type-III-A-CRISPR-associated-protein-Csm6	gnl\|CDD\|131720	TIGR02672, hypothetical_protein_SERP2456, CRISPR type III-A/MTUBE-associated protein Csm6. Members of this family as found in CRISPR-associated (cas) gene regions in Streptococcus thermophilus CNRZ1066, Staphylococcus epidermidis RP62A, and Mycobacterium tuberculosis (strains CDC1551 and H37Rv), as part of Mtube-type CRISPR/Cas systems. CRISPR is a widespread form of direct repeat found in archaea and bacteria, with distinctive subtypes each of which has a characteristic sporadic distribution.	8.70579e-117
NZ_CP048279.1\|WP_162680864.1\|156002_156662_+\|4'-phosphopantetheinyl-transferase-superfamily-protein	gnl\|CDD\|225002	COG2091, Sfp, Phosphopantetheinyl transferase [Coenzyme metabolism].	7.74756e-27
NZ_CP048279.1\|WP_162680857.1\|139029_139782_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|227838	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	8.47053e-11
NZ_CP048279.1\|WP_162680859.1\|143085_143937_+\|MurR/RpiR-family-transcriptional-regulator	gnl\|CDD\|224651	COG1737, RpiR, Transcriptional regulators [Transcription].	1.23609e-60
NZ_CP048279.1\|WP_162680849.1\|131246_132155_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	4.20406e-96
NZ_CP048279.1\|WP_162680850.1\|132154_132460_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|273699	TIGR01573, cas2, CRISPR-associated endonuclease Cas2. This model describes most members of the family of Cas2, one of the first four protein families found to mark prokaryotic genomes that contain multiple CRISPR elements. CRISPR systems protect against invasive nucleic acid sequences, including phage. Cas2 proteins have been characterized as either endoribonuclease (for ssRNA) or endodeoxyribonuclease (for dsDNA), depending on the system to which the Cas2 belongs. CRISPR is an acronym for Clustered Regularly Interspaced Short Palindromic Repeats. The cas genes usually are found near the repeats. A distinct branch of the Cas2 family shows a very low level of sequence identity and is modeled by TIGR01873 instead of by this model (TIGR01573).	1.24708e-20
NZ_CP048279.1\|WP_162680863.1\|148864_155992_+\|amino-acid-adenylation-domain-containing-protein	gnl\|CDD\|237108	PRK12467, PRK12467, peptide synthase; Provisional.	0
NZ_CP048279.1\|WP_162680853.1\|135176_135821_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl\|CDD\|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	2.7701e-99

>NZ_CP048279.1|WP_162680857.1|139029_139782_+|CRISPR-associated-endoribonuclease-Cas6
MINKLTIELSLPSNIKPNYLGSILHGVIMDYLSTDMAAQLHHYYAYSPLKQRIYLKNHLIIWEIISMNDNLSGELIEIFSKNETLFLKHYHTHIQLKTFIVTKFNIKEMMNGFLGKDDLSRFIHIKIQTPMSFKMKNEYLIFLDINRFFRSIMIQFDSFFDNYKMYDKETLDFIESNVKIVDYKLKSTKFYLEKVKIPSFTGELSLKVKGPLPFLQLIYFLLEFGELSGVGIKTSLGMGKYSIIERENKK
>NZ_CP048279.1|WP_162680856.1|137764_139033_+|type-III-A-CRISPR-associated-protein-Csm6
MKILFSPIGNTDPWSNYRDGAMLHIVRQYRPDKIVLFFTESIWNGNENMPGRKEFNWNKIISSVSPDSKVEIKIDKVENEHDFDSYKELFHNYILEIMNEEPNAEVLLNVTSGTPQMESTLCLEYVTYPNHKECIQVATPEPEKNIKRIFANPNDQEEALQKVNENEMNSKIRSKSIDIISFREAMIRSQIIGLIYNYDYEAALTLISEQKSFRNAKNLRKKLLLMTTQVKTHEIFPEINASYNNKALKKVLFHYLILKMRYDRQDVAETLIRVKSIAEFIIRDYIEVHYPNIIIEENGKPYLNTNDNMPFLMKYQKRLKNEYKSYVPQRILSLPTFIDILKVLSPKSPLLKELLAINDVNGLRNSVAHHLDTLKLDRNKNHTKIRLSVESIKNMLNIAYPEIDEKDFNYFEEKNKELIGLL
>NZ_CP048279.1|WP_162680855.1|136743_137748_+|type-III-A-CRISPR-associated-RAMP-protein-Csm5
MSIKVYEATIKTVGPVHIGSGRTIRKQDYIYDFHKSMVHMVNGAELVKFLKGKDLLDDYQKFLRHPPKKPRESGLKNFLDAHRIKQDEWKTFIKFSEQVHQGKKHGTYKPKPLNDIHLMMRDGQNQVYIPGSSIKGAIKTAVVSKYNEAEKDIFSKIKVSDSEPIDECHLAIYQKIDINKVDKPMPLYRECIDVNTEIKFTLSLEDDIYTIEDIEECIQSFYKNYYNEWLIGFKETNGGRRFSIEGGMPALVGENVLYLGAGTGFVSKTTHYQLKNRLQAKKDSFEILRKKFSSTYGKMKEIPKNVPVVLKGTINEIKKEAYQQGMCMITFNSK
>NZ_CP048279.1|WP_162680854.1|135831_136740_+|type-III-A-CRISPR-associated-RAMP-protein-Csm4
MNFEIFKLYFKTPVHFGKKRLSDGEMTISADTLFSALFIESLQMGINTDWLLNDLVISDTFPFESELYYLPKPLIKIESKEEGNHKDFKKLKYIPVYNYMDYIQGHLQANDAKDLNEIFNIGHFSLQTKVSLISQETDPDADSEPYSIGTFTFEVNAGLYFIAKGSDKTLEKLKVVMNTLQFSGIGGKRFAGLGRFEVQNVNDSSLNQLLSNKGVKHILLSTAMAKEHELEASCEDARYTLKKRSGFIQSVNYSETLVKKNDFYSFSAGSVFTNPFKGDIFNVGMEGQHPVYRYGKPLWLEV
>NZ_CP048279.1|WP_162680853.1|135176_135821_+|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MYSKIKITGTIEVVTGLHIGGGGESSMIGAIDSPVVRDLQTKLPIIPGSSIKGKMRSLLAKNYGLKMKQENHNDDHENVLRLFGSSEKGNIKRARIQISDAFYSDKTKKLFAEKDIAYTETKFENTINRLTAVANPRQIERVTRGSEFDFTFIYNVDDESEVEKDFENIKRALSLLENDYLGGGGTRGNGRIQFKDILIETVIGDYDSSKLRIK
>NZ_CP048279.1|WP_162680852.1|134749_135175_+|type-III-A-CRISPR-associated-protein-Csm2
MILAKTTSGKNIDLNFAHEVIKNNVKKYRDKPGKEKEELFGGLTTSKLRNLMEQVNRLHTIAFNSNEEKLSDKFLDELEYLKVKFYYEAGREKSVDEFLKKTLMFPIIDKVIKKESREFFLDYCKYFEALVAFAKYYQKED
>NZ_CP048279.1|WP_162680851.1|132473_134747_+|type-III-A-CRISPR-associated-protein-Cas10/Csm1
MNKKTSLMYGALLHDIGKIIYRSNNHPFAKGTHSKLGRLFLSKFSGFKNNDILDCVSYHHFKELSKVKLDKDNPAYITYIADNIASGIDRRDVIEEGDQENEKHAFNFDKNTPLFSVFNIVNSQTQGQTEGKFIFSKESHIEYPKNEEVQYTSGNYTQLMEDMKQDLIEKIKVNEHHFSSLLQWTESLWQYVPSSTNKNQLVDISLYDHSRITCAIASCIYDYLTEKNICDFQNELFSNYKKTQAFYDENAFLLLSMDMSGIQDFIYNISGSKALKSLRSRSFYLEIMIEVIVDEFLYRVGLSRANLLYTGGGHAYLIVPNTNYVKEQVELFQYDIKEWFIQEFTTDLSLSIAYEACSGNDLMNSNGNYKTIWRNVSNKLSDMKSQKYTAKDILRFNHEHSHGDRECKECLRSDTEINEEGLCSVCEGIISISNDLRDKSFFVVSNSGKLKMPFNNFLNVLNYEEAETLANHDDNAKIYSKNEPFVGQGISTNLWMCDYDYASQYEEMKYSGISSYAERSVGIRRLGVVRADIDNLGTIFISGIPENYNSLSRTATLSRQLSLFFKYELTNLLKGYQITAIYSGGDDLFLIGAWDDIVEASIHINDRFNAFTMGKLTISAGIGMFNAKYPISKMAFETGLLEEAAKTGDKNQVALWMNEKVYGWKELKEQVLKEKLSLIQEAFKTTDKHEKAFIYKILVLLRNKEQINIARLAYLLSRSKMTNDFSSLVFKWAQEEQEKEELITALEYYIYQIREAE
>NZ_CP048279.1|WP_162680850.1|132154_132460_+|CRISPR-associated-endonuclease-Cas2
MILLVCFDLSRETRLDRKKANKYRERLLELGFSMKQFSLYERYISTAQKKDKLLEILQKEIPDTGSITLYMLPDEVNNKQITILGKNAELIKEREPKLIFL
>NZ_CP048279.1|WP_162680849.1|131246_132155_+|type-II-CRISPR-associated-endonuclease-Cas1
MKDIIYVESHYFVTVKNESLKFKNIIDKNERFYLLDDIEALVFDSPRSYYSQKLIVKCVEYNILVLFCDLKHSPIAEIISDFAMVNRLQRIQDQLQVLSKTKDRLWKKIVANKIINQAKCIENNVNKGSTAKSLCEYARSVGPGDRTNRESVAARLYFQSLYGKNFKRGRYDDKINSALNYGYSILRSFIKKELAIHGFEMSLGIKHHSTENPFNLADDIIECYRPFVDSMVYDLIFNCHISSFGVTEKKKMLEVLYENCLIDKKIVKLVDSIKLTVQSLIKCYKQNTPTHLLLPKLIEVGN
>NZ_CP048279.1|WP_162680848.1|130166_130835_-|response-regulator-transcription-factor
MQYEALIIEDDIDIAHILSLTLTKMNIKAHIVYSGLEAQACIEKNTYDLILLDLMLPEVTGEEILPIIKANTNSKIIVISAKVDIEEKVHLLHKGADDYITKPFDIKEVAARVAVQLRNLEHHKNPEVLVWKDLRLDLTKHQAYIKNIEMNLTNTEYDILTLLMSQPENAFSKQKIYEKVQGIYFGDDNTINVHISNIRKKISKHTNETYIKTVWGIGFMLI
>NZ_CP048279.1|WP_162680858.1|142285_142654_+|hypothetical-protein
MRQAIPQAAVGAIQRAQHLVAVGDPVQIEPVVTIDRNLIDFVRKAFNVPERLVSIESSVQTLSDGANLYGYWKGEDAEKQWIGIPLWVYRRCLNPMFTISNTIAICEGARYSRSRRIKKRLA
>NZ_CP048279.1|WP_162680859.1|143085_143937_+|MurR/RpiR-family-transcriptional-regulator
MGVLSHMKSMQSEMSAAERKIFQFIYNNSEKIASMTANDIAKASGASSPTVVRFSKKMGYNSLTELKIELSAEAKKVPSVNTYSDVDQDESFYSLKNKLASNARYTIDETTALFNEKQFLDACKFIEEKEYCYVLGIGASSLTAMDIVQKWGRLGKNIVSEPDYNTVLPQLILHQKDCVIWLVSNSGLTSELISLAETAKDLNIPIITLTQFGQNPLSKLADVNLQTSRPMESIYRSAATDSILAQFITVDLLFYVYISRNRENAEKIYTTRSIVEEYRKKYF
>NZ_CP048279.1|WP_162680860.1|144038_146009_-|PTS-transporter-subunit-EIIC
MGKEELTLNELAKEIYAGAGGLENVQTVNHCMTRIRMNIYDNHKVDQRKLKSIPGVLGVIFDEQLQVIIGPGKVTKVANEMVSLAGVDLGENINKSSGKERVNANAAKMKAAQKAKQKNSPLRSILKDISNIFVPMIPAFVGSGLIAGIAAVMNNLITAGTLSATTWQQFVDILNILKNGMFAYLVIYTGINAAKVFGANQTLGGVIGAVVTLTGMNVDKPIKNLITGDALTAGQGGIIGVIFAIWLLSIIEKKLHKIIPDSVDIIFTPTLSLLIVGLLEIFLIMPLAGLISNVLVGGINWVLSVGGPFSGFVLGSLFLPMVMFGLHQILTPIHIQMINETGMTLLLPILAMAGAGQVGAAIALWVKLRKDTELTEMIKGALPVGVLGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGAIGGIGSIAIGPSGIALIPLISNNHWIGYILGLISAYIGGFIVTYFLGIPKDKLLEQSPIDSKISTVAVNQVKDNKTDNKISKQETEFFNAVTTGSLHPLEESTDPVFSKRMMGEGYFIIPTDEEIFSPVSGTISTIFPTKHAIGITTDNGLEVLLHMGVNTVELNGLPFDVFITEGQKVTTDSKIAKLDLRAIKTANKDTSIMVVITNMEKVDSYKLESCGSVTPTDTVFSVTTH
>NZ_CP048279.1|WP_162680861.1|146025_146922_-|N-acetylmuramic-acid-6-phosphate-etherase
MKMINLDNLTTEHRNENSYNLDEMSLGLALKKMNQEDQKVALAISEQLTQIEKLIDAATENLKKGGRLIYMGAGTSGRLGVLDAVECVPTFGADTDMIIGLIAGGNKAMISAIEGIEDDIDQGKKDLMSLRLTKNDMVIGVTASGRTPYVIGGINYAQSIGAQTGSLSCNKNSEISMIANFPIEVDCGPEFLTGSTRLKSGTAQKMVLNMISTVSMIGIGKVYKNLMVDVKPTNRKLIERSKRIIMQATEVNYVTATRYFEEANQNVKLAIVMILTNSNKEEATKKLVKADGFIRRTI
>NZ_CP048279.1|WP_162680862.1|146908_147982_-|DUF871-domain-containing-protein
MFGFSVFLNQPLSTEIKQYIEKMATSGFTGVFTSLHIPEDNNTHYHKLLIELGNITKSLNLDLMVDISSSSLQNAGFSVNRINELQSIGVTGLRADDNISIKSIAQLSNKITIALNASTITSNDIQELKLANANFDRLEAWHNYYPRSETGLDEEWYRKKTKWLKTLGLKTQAFVPGNNNLRGPLYQGLPTLEKHRNYHPLAASLDLLSETDKIFIGDPGLSDSVLNQFANYIQKNNILLHVDSFSNQIDFALGEHTNRLDEARDVIRSAYSRKKKITNIQPLLNIKRDTGSVTIDNSKYLRYMGEIQITKYSLPADEKVNVVGQVSQNDQHLIQFIKGGQKFTLIKNDIESEDEND
>NZ_CP048279.1|WP_162680863.1|148864_155992_+|amino-acid-adenylation-domain-containing-protein
MTQQYESVLFNRDPSTPPHSYVVHLPKSLDIQRLLYALTQLVQTQSLLRASFTYVEGELKYRIRQFAPFIEVVHEARALSDLNFEVDLEHNAFDTTIPTTAPLFAFKIICLTDCMLLQFNVSPLIFDEASMPIFLSQLSHYYENPFQSITLTPSFSELIQQMHQLRRLPSFKMQLQQWQSQQVVQDTYHAYMPVQSLTNENHTQWQTVKIQHDKVNLDDIYSSIILANHFIGRSDDVHVGLTTMRTPSFDQGDAIGPRIRILPGNFHVDRTLSYQQFKTRLSSQINTIVNEEVLHLTDLIEAHTGFPFETLIHSEPIHYTFEIAGEVCKAERLKPIETEAALDVYVQEVEDGYVVKMLYNRDQYDDLTIETYANLIRHLCLQGATRPEVPMNSFSLMTTAQDEAILQQLLRTESDIFATVPELFAEQVQRHPDKVAVRFENDSITYAQLDRLTNQVARQIRARGVKPNDYIAVMAERSMEMIVAVLGIVKSGAAYVPIDPDYPEARIQYILEDVQPALFVLHQVDFDTTAPTVLLKDLQVGSDATVPVVNHCDDDVYVIYTSGTTGQPKGTRIMHQSVDRLVKGVDYVPLNEATKILLSGTIAFDAVTFEIYGALLNGGELVVLSKDQLLNPKALEQAIQKYEINTMWLTASLFNATVSTHVEALEPLSYLLVGGEALTRKWVELLHQRPHHPQIINGYGPTESTTFTTTYTMPETIPARIPIGKPIRETDIYILQGTQRCGIGVPGELCIGGAGLAKGYLNRPELTASRFIDHPFGTGKLYRTGDLVRLQPDGEIDYLGRLDKQVKIRGFRIELTEIERAIERIHGVNKAVVVTREVEGDKQLYAFYEGEQEISNQTMTTTLSAQMPSYMVPLSFQRIDQIPMTVNGKLNTQALPDPETRLQSHYEAPRNEMEQVLCHIFEEVLHIERVDIHDHFFELGGHSLKATLVVNRIEREWHKPMTVADLMKYPTVASLSERLEGMSESQTETMPIVTSNQQAYPASAAQRGMYFLWQLDPDDTVYNVPFIWRLSAPLDIEKLRHAVSQLIERHEILRTQFGMDNQQVYQYIQDCHIPDFEVVTLEEHDPQVLVECMMQPFDLENDRLLRIRYIQTPEDDFLFMDTHHSVNDGMSQTIILDELNQLYQDKPLPTTTHQYKDYSAWSNQREMTNHQTYWHELLKETPPTLELPLDYPRPHVKSTKGEMYQWQLDEDLSQKIKQYVQQHDVTDFMFFMSVIMVLLSQYSRQEEIVLGSVMSARTHPDTERMLGMFANSVVFKGQPTRNKPWLTFLDEMKTMSLAAYAHQDYPFSVLVDDLIAQRDASRHPFFDVIVIRQNNEAHHAHFGHSRLIHQHPKSTTAKFDLSFIIEEDNHQFAWNIEYRTDLFHKETIQHMCDQFEVMIQAILDRTALRIGELPIAKLDMHQWVEAHVTPQPMAYPEQETVGNRIKQLALQAPEATAMIFGNQHHSMQMLYQRALAIARHLYEQGCRKGDRVALLMTRGPEMIESMIAAALLGCPYVPIDTDYPKTRIEFILKDAQVKHILTNVPPRFTTAATLDVRSCVTQEDDAQVIQSSEHVEANDVLYMIYTSGTTGQPKGVQITHHNVMNLVTGWSQNIKLTSDDVILQYANIVFDASVMEIYCALFNSCPLVIASEQERKDIFALEQCLRTQHVTVALIPAQLCMMMTDYHLRCLITGGSVSTPELVERVRPHCEMYANAYGPTESTVITTAWIDDGQSALQRVPIGRPLPNIQVYIVSEGRLCGVGIPGELCIAGDSLAKGYLNRPEVNAQAFIPNPWGDGQLYRTGDLARYLNNGEIEFLGRIDQQEKINGYRIELEEITNQMNRVDGILDSVVKVDRTHEHAQLVGYYVAEKDQSDALRYALTAQLPQYMVPQIFIRLEELPLTPNGKLDVKALPDVHSQLDRAVTMPRNQTEQQLVDVFEQVLNVTPIGIDNDFFELGGNSIATMKVVMLLKNKGIDMDMQDIYQYKTIRALVAQNEPTQLDVPGNIDVLQTMIATNQTPLSEVSQQSLGTVLLTGATGFLGAYLLYELTERYQRVHCLIRAESELQARERLIDNLSYYFDSSTREKMMRNVDIIHGDTNQDFTQLATSIDTIIHAAARTDHFGEDDEFYEANVKSTVDLIALAKRAQAQLIYISTLSVAGDFSEEQEDTQFSETTIFKDQRITSPYARSKFYAELEVLEAMRQGLKVKIMRVGNLTSSRHGNITMKNMRTNRFSIVMHDLLQLDKIGISAAQTPISFSFVDEAAQMIIQFAEIQQSTYNTFHITNHHEYTMQSMLEKLTNRTIKVVDDATFEQYVHDAGYYAWVGLMHHDDKLKPAIITQDFTLSVMKELDLSWSELSEAWLARWQQRLNDTFK
>NZ_CP048279.1|WP_162680864.1|156002_156662_+|4'-phosphopantetheinyl-transferase-superfamily-protein
MIFIVNLEKMTNAMTKQLAHKQYLFKRNHTKHHYKSNENQHRVGELLVHYGLRKMYQLESLDWQFKFGTYGKPYIDSPQPVFISLSYSGNYVACAFDQSEIGLDIENLSPIEWQRLKIQFTKEEAHWIDNETQFYMIWTQKEAYAKLTGKGLSEGVATNNVLEPLYYHGQPIAFQTQIKDTLMIQLCQTKPCTQTPMIEVDLETLLASSYMDHPGSFTH
>NZ_CP048279.1|WP_162680865.1|157044_157872_+|autolysin
MLKMFSVLSTSLTLLLMPMVFAPTTYARSLFSRPLPSSTLAQTVPTMMLMNHDEHDSPSQNSTENNAPGTETAHQDQQNRTLPPLDYPNVNQYIIEHHLPHSKIVKDPRMNTLPHLPYRYGTYMGVVIHEVGEDNRTLQQWVDRMYATYYRAFVHAFVDNNEIHLTAPSEYYVWGAGKQANPYFYQIEVVRMYTFDDFARSVNNQAWLAAYMLKQNHLTPTLADDQEGVGSVISHNAVRKYWGGTTHVDPIAYYARWGYDMHQFFDLVKYHYNHM
>NZ_CP048279.1|WP_162680866.1|158240_158441_+|hypothetical-protein
MEALFEFVKSLSYIIVSIPTSYFIAFGVTIYALMLCIFLVRAPIKTFFDRHYYGGDSDQMPFVAGP
>NZ_CP048279.1|WP_162680867.1|158610_161406_+|type-I-restriction-endonuclease-subunit-R
MAYQSEFALENDVLKQLTQMGYEQLNIHTHDEMLQNFRAIINERHIKALNHQPLTDSEFDRLITDINGKSVFDSAVILRDKYVLKRDDETVVYLSFLDQNKWCQNKFQVTNQVSVKDTYKSRYDVTILINGLPLVQIELKRSGVAISEAFNQVERYRKQNFTGLFRYIQLFVISNKMETRYYANSDLTILKSHMFYWSNEKNERINYLKSFIEDFLEPCHLAKMISRYMIVNETDKILLALRPYQVYAVEKLIERSLETNNNGFIWHTTGSGKTLTSFKASQILSQQEGIKKVIFLVDRKDLDSQTLAEFNKFQEDSVDLTDSTRKLLKQLGDATLPLIVTTIQKMVHAIKSNHPVMNQYEHDKVIFIIDECHRSQFGDKHRLVKRHFKNAQYFGFTGTPRFEENKSQDGRATADIFDKCLHHYLIKDAIRDGNVLGFSVDYARTFDPKKDLKEEYVNKINEKEVWMAEERISKITEHIIENYAKKTRDGHYTSMLTVQSIPMAIAYYEAFKKAKEAGKHDLNVTTIFTFRPNEDSNEQEDFVHSREMLDRVMVDYNAMFGTNFNTDYFDGFFSDVSKKMKKVIPGEKIDILIVVDMFLTGFDSKKLNTLYVDKNLKYHNLIQAYSRTNRVEKETKPYGNIVCYRDLKAETDQAIEIFSQTDNTDTVLSGSFEEYLDDFKEVLKQLFALVITPADVDKLDREDDQKEFVLIFRALASLLLKLKTFEEFEFTQEQVGISEQTFEDYKSKYLNLYEKVVKSNKEETEGVSILGDIDFKVEILRNDLINVQYIMNLIGQIELQDKAEQNRNRKQIHQLLDRADDEQLRLKADLIRQFLDKVVPTLKEGTDVNEAYYQYEEAEKYKEIEAFAEDKAYPSQLLGHIIEEYEYSGSINKNTIDKGLENQDGFLAKTKTANKIKSFVMETVQKYGSTE

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Crispr_ID: NZ_CP048279_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP048279_2

2091792-2092420

TypeII

Consensus_repeat	Method
GTTTTACTTCTTTCTAAATAAACATAGTGCTAAAACA	PILER-CR
NGTTTTACTTCTTTCTAAATAAACATAGTGCTAAAAC	CRT
GTTTTACTTCTTTCTAAATAAACATAGTGCTAAAAC	CRISPRCasFinder
GTTTTACTTCTTTCTAAATAAACATAGTGCTAAAAC	PILER-CR

9 spacers

cas2,cas1,cas9

The CRISPR arrays of NZ_CP048279_2

>merge|NZ_CP048279|2|2091792-2092420|PILER-CR,CRT,CRISPRCasFinder,PILER-CR
GTTTTACTTCTTTACTAAATAAACATAGTGCTAAAACAGAAAATCTATTTATAGCGAGAAGCCCCCTGTTTTACTTCTTTCTAAATAAACATAGTGCTAAAACACATTCTAATACCTAAAATCGCATAAATAGTTTTACTTCTTTCTAAATAAACATAGTGCTAAAACACGGTTGAAGATATTAAAGATGAGCTAGCCAGTTTTACTTCTTTCTAAATAAACATAGTGCTAAAACAATGCTCCAAAAGCAGAAAGCACAGATTCGGTTTTACTTCTTTCTAAATAAACATAGTGCTAAAACTCTTATCAATACTTCGATAGCGTTCGTTCAGTTTTACTTCTTTCTAAATAAACATAGTGCTAAAACAATGCTCCAAAAGCAGAAAGCACAGATTCGGTTTTACTTCTTTCTAAATAAACATAGTGCTAAAACCAACGTAACCACGACACAGATGCCGGCTTGTTTTACTTCTTTCTAAATAAACATAGTGCTAAAACATAGCCTCTGCAACTTCTTTATGCTTTATGTTTTACTTCTTTCTAAATAAACATAGTGCTAAAACTAAGTGTACTTATAGTGTGCTATTTCTTCAGTTTTACTTCTTTCTAAATAAACATAGTGCTAAAAC

>NZ_CP048279|2|2|2091792-2092027|PILER-CR
GTTTTACTTCTTTACTAAATAAACATAGTGCTAAAACA	GAAAATCTATTTATAGCGAGAAGCCCCCT
GTTTTACTTCTTTCTAAATAAACATAGTGCTAAAACAC	ATTCTAATACCTAAAATCGCATAAATAG
TTTTACTTCTTTCTAAATAAACATAGTGCTAAAACACG	GTTGAAGATATTAAAGATGAGCTAGCCAGT
TTTACTTCTTTCTAAATAAACATAGTGCTAAAACAATGCTCCAAAAGCAGAAAGCACAGATTCGGTTTTACTTCTTTCTAAATAAACATAGTGCTAAAACTCTTATCAATACTTCGATAGCGTTCGTTCAGTTTTACTTCTTTCTAAATAAACATAGTGCTAAAAC	AATGCTCCAAAAGCAGAAAGCACAGATTCG
GTTTTACTTCTTTCTAAATAAACATAGTGCTAAAAC	CAACGTAACCACGACACAGATGCCGGCTT
GTTTTACTTCTTTCTAAATAAACATAGTGCTAAAAC	ATAGCCTCTGCAACTTCTTTATGCTTTAT
GTTTTACTTCTTTCTAAATAAACATAGTGCTAAAAC	TAAGTGTACTTATAGTGTGCTATTTCTTCA


>NZ_CP048279|2|2|2091792-2092420|CRT
GTTTTACTTCTTTACTAAATAAACATAGTGCTAAAA	CAGAAAATCTATTTATAGCGAGAAGCCCCCT
GTTTTACTTCTTTCTAAATAAACATAGTGCTAAAAC	ACATTCTAATACCTAAAATCGCATAAATA
GTTTTACTTCTTTCTAAATAAACATAGTGCTAAAAC	ACGGTTGAAGATATTAAAGATGAGCTAGCCA
GTTTTACTTCTTTCTAAATAAACATAGTGCTAAAAC	AATGCTCCAAAAGCAGAAAGCACAGATTCG
GTTTTACTTCTTTCTAAATAAACATAGTGCTAAAAC	TCTTATCAATACTTCGATAGCGTTCGTTCA
GTTTTACTTCTTTCTAAATAAACATAGTGCTAAAAC	AATGCTCCAAAAGCAGAAAGCACAGATTCG
GTTTTACTTCTTTCTAAATAAACATAGTGCTAAAAC	CAACGTAACCACGACACAGATGCCGGCTT
GTTTTACTTCTTTCTAAATAAACATAGTGCTAAAAC	ATAGCCTCTGCAACTTCTTTATGCTTTAT
GTTTTACTTCTTTCTAAATAAACATAGTGCTAAAAC	TAAGTGTACTTATAGTGTGCTATTTCTTCA
GTTTTACTTCTTTCTAAATAAACATAGTGCTAAAAC

>NZ_CP048279|2|2|2091793-2092420|CRISPRCasFinder
TTTTACTTCTTTACTAAATAAACATAGTGCTAAAAC	AGAAAATCTATTTATAGCGAGAAGCCCCCT
GTTTTACTTCTTTCTAAATAAACATAGTGCTAAAAC	ACATTCTAATACCTAAAATCGCATAAATA
GTTTTACTTCTTTCTAAATAAACATAGTGCTAAAAC	ACGGTTGAAGATATTAAAGATGAGCTAGCCA
GTTTTACTTCTTTCTAAATAAACATAGTGCTAAAAC	AATGCTCCAAAAGCAGAAAGCACAGATTCG
GTTTTACTTCTTTCTAAATAAACATAGTGCTAAAAC	TCTTATCAATACTTCGATAGCGTTCGTTCA
GTTTTACTTCTTTCTAAATAAACATAGTGCTAAAAC	AATGCTCCAAAAGCAGAAAGCACAGATTCG
GTTTTACTTCTTTCTAAATAAACATAGTGCTAAAAC	CAACGTAACCACGACACAGATGCCGGCTT
GTTTTACTTCTTTCTAAATAAACATAGTGCTAAAAC	ATAGCCTCTGCAACTTCTTTATGCTTTAT
GTTTTACTTCTTTCTAAATAAACATAGTGCTAAAAC	TAAGTGTACTTATAGTGTGCTATTTCTTCA
GTTTTACTTCTTTCTAAATAAACATAGTGCTAAAAC

>NZ_CP048279|2|3|2092123-2092420|PILER-CR
	GAAAATCTATTTATAGCGAGAAGCCCCCT
GTTTTACTTCTTTCTAAATAAACATAGTGCTAAAACAC	ATTCTAATACCTAAAATCGCATAAATAG
TTTTACTTCTTTCTAAATAAACATAGTGCTAAAACACG	GTTGAAGATATTAAAGATGAGCTAGCCAGT
TTTACTTCTTTCTAAATAAACATAGTGCTAAAACAATGCTCCAAAAGCAGAAAGCACAGATTCGGTTTTACTTCTTTCTAAATAAACATAGTGCTAAAACTCTTATCAATACTTCGATAGCGTTCGTTCAGTTTTACTTCTTTCTAAATAAACATAGTGCTAAAAC	AATGCTCCAAAAGCAGAAAGCACAGATTCG
GTTTTACTTCTTTCTAAATAAACATAGTGCTAAAAC	CAACGTAACCACGACACAGATGCCGGCTT
GTTTTACTTCTTTCTAAATAAACATAGTGCTAAAAC	ATAGCCTCTGCAACTTCTTTATGCTTTAT
GTTTTACTTCTTTCTAAATAAACATAGTGCTAAAAC	TAAGTGTACTTATAGTGTGCTATTTCTTCA
GTTTTACTTCTTTCTAAATAAACATAGTGCTAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP048279.1\|WP_162682317.1\|2079830_2080907_-\|alanine-racemase	unknown	unknown	gnl\|CDD\|143490
NZ_CP048279.1\|WP_162682322.1\|2087316_2087808_-\|Asp23/Gls24-family-envelope-stress-response-protein	unknown	unknown	gnl\|CDD\|377129
NZ_CP048279.1\|WP_096555582.1\|2105223_2105538_-\|PTS-lactose/cellobiose-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|129903
NZ_CP048279.1\|WP_162682326.1\|2092609_2093458_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048279.1\|WP_162682318.1\|2080910_2082680_-\|siderophore-synthetase	unknown	unknown	gnl\|CDD\|226715
NZ_CP048279.1\|WP_162682324.1\|2088945_2090460_-\|BCCT-family-transporter	unknown	unknown	gnl\|CDD\|376718
NZ_CP048279.1\|WP_162682320.1\|2083948_2085916_+\|sialic-acid-synthase	unknown	unknown	gnl\|CDD\|226715
NZ_CP048279.1\|WP_162682325.1\|2090516_2091527_-\|zinc-binding-alcohol-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|176214
NZ_CP048279.1\|WP_162683043.1\|2093454_2093748_-\|CRISPR-associated-endonuclease-Cas2	cas2	mkCas0206_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|226043
NZ_CP048279.1\|WP_162682319.1\|2082663_2083848_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340863
NZ_CP048279.1\|WP_019165072.1\|2087862_2088108_-\|DUF2273-domain-containing-protein	unknown	unknown	gnl\|CDD\|227834
NZ_CP048279.1\|WP_162682330.1\|2100189_2101398_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|341042
NZ_CP048279.1\|WP_162682333.1\|2103484_2105218_-\|PTS-transporter-subunit-EIIC	unknown	unknown	gnl\|CDD\|273055
NZ_CP048279.1\|WP_162682331.1\|2101405_2101825_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_CP048279.1\|WP_162682328.1\|2094691_2098696_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	mkCas0193_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|273840
NZ_CP048279.1\|WP_162682323.1\|2088120_2088663_-\|alkaline-shock-response-membrane-anchor-protein-AmaP	unknown	unknown	gnl\|CDD\|380217
NZ_CP048279.1\|WP_162682329.1\|2098950_2100171_-\|carboxylesterase-family-protein	unknown	unknown	gnl\|CDD\|225181
NZ_CP048279.1\|WP_162682332.1\|2102063_2103467_-\|6-phospho-beta-galactosidase	unknown	unknown	gnl\|CDD\|184102
NZ_CP048279.1\|WP_162682321.1\|2086026_2087172_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|225371
NZ_CP048279.1\|WP_162682327.1\|2093826_2094702_-\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694

Protein	Function_ID	Function_description	E-value
NZ_CP048279.1\|WP_162682317.1\|2079830_2080907_-\|alanine-racemase	gnl\|CDD\|143490	cd06815, PLPDE_III_AR_like_1, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase-like 1. This subfamily is composed of uncharacterized bacterial proteins with similarity to bacterial alanine racemases (AR), which are fold type III PLP-dependent enzymes containing an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain. AR exists as homodimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. It catalyzes the interconversion between L- and D-alanine, which is an essential component of the peptidoglycan layer of bacterial cell walls. Members of this subfamily may act as PLP-dependent enzymes.	2.15976e-118
NZ_CP048279.1\|WP_162682322.1\|2087316_2087808_-\|Asp23/Gls24-family-envelope-stress-response-protein	gnl\|CDD\|377129	pfam03780, Asp23, Asp23 family, cell envelope-related function. The alkaline shock protein Asp23 was identified as an alkaline shock protein that was expressed in a sigmaB-dependent manner in Staphylococcus aureus. Following an alkaline shock Asp23 accumulates in the soluble protein fraction of the S. aureus cell. Asp23 is one of the most abundant proteins in the cytosolic protein fraction of stationary S. aureus cells, with a copy-number of >25000 per cell. A second Asp23-family protein, AmaP, which is encoded within the asp23-operon, is required to localize Asp23 to the cell membrane. The overall function for the family is thus a cell envelope-related one in Gram-positive bacteria.	1.16463e-34
NZ_CP048279.1\|WP_096555582.1\|2105223_2105538_-\|PTS-lactose/cellobiose-transporter-subunit-IIA	gnl\|CDD\|129903	TIGR00823, PTS_system_lactose-specific_IIA_component, phosphotransferase system enzyme II, lactose-specific, factor III. The PTS Lactose-N,N?-Diacetylchitobiose-b-glucoside (Lac) Family (TC 4.A.3)Bacterial PTS transporters transport and concomitantly phosphorylate their sugar substrates, and typically consist of multiple subunits or protein domains.The Lac family includes several sequenced lactose (b-galactoside) permeases of Gram-positive bacteria as well as the E. coli N,N?-diacetylchitobiose (Chb)permease which can transport aromatic b-glucosides and cellobiose as well as the chitin disaccharide, Chb, but only Chb induces expression of the chboperon. While the Lac permeases consist of two polypeptide chains (IIA and IICB), the Chb permease of E. coli consists of three (IIA, IIB and IIC). In B. subtilis, a PTS permease similar to the Chb permease of E. coli is believed to transport lichenan (a b-1,3;1,4 glucan) degradation products, oligosaccharides of 2-4 glucose units. This model is specific for the IIA subunit of the Lac PTS family. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	8.37522e-46
NZ_CP048279.1\|WP_162682318.1\|2080910_2082680_-\|siderophore-synthetase	gnl\|CDD\|226715	COG4264, RhbC, Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism].	2.97798e-78
NZ_CP048279.1\|WP_162682324.1\|2088945_2090460_-\|BCCT-family-transporter	gnl\|CDD\|376718	pfam02028, BCCT, BCCT, betaine/carnitine/choline family transporter.	0
NZ_CP048279.1\|WP_162682320.1\|2083948_2085916_+\|sialic-acid-synthase	gnl\|CDD\|226715	COG4264, RhbC, Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism].	1.85791e-93
NZ_CP048279.1\|WP_162682325.1\|2090516_2091527_-\|zinc-binding-alcohol-dehydrogenase-family-protein	gnl\|CDD\|176214	cd08252, AL_MDR, Arginate lyase and other MDR family members. This group contains a structure identified as an arginate lyase. Other members are identified quinone reductases, alginate lyases, and other proteins related to the zinc-dependent dehydrogenases/reductases. QOR catalyzes the conversion of a quinone and NAD(P)H to a hydroquinone and NAD(P+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR acts in the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	2.90304e-155
NZ_CP048279.1\|WP_162683043.1\|2093454_2093748_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	9.9751e-25
NZ_CP048279.1\|WP_162682319.1\|2082663_2083848_-\|MFS-transporter	gnl\|CDD\|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.72666e-54
NZ_CP048279.1\|WP_019165072.1\|2087862_2088108_-\|DUF2273-domain-containing-protein	gnl\|CDD\|227834	COG5547, COG5547, Small integral membrane protein [Function unknown].	3.95841e-17
NZ_CP048279.1\|WP_162682330.1\|2100189_2101398_-\|MFS-transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	9.96805e-73
NZ_CP048279.1\|WP_162682333.1\|2103484_2105218_-\|PTS-transporter-subunit-EIIC	gnl\|CDD\|273055	TIGR00394, lac_pts_IIC, phosphotransferase system, lactose specific, IIC component. This family of proteins models the IIC domain of the phosphotransferase system (PTS) for lactose. The IIC domain catalyzes the transfer of a phosphoryl group from the IIB domain to lactose. When the IIC component and IIB components are in the same polypeptide chain they are designated IIBC. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids, Signal transduction, PTS].	0
NZ_CP048279.1\|WP_162682331.1\|2101405_2101825_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	8.68549e-14
NZ_CP048279.1\|WP_162682328.1\|2094691_2098696_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|273840	TIGR01865, conserved_hypothetical_protein, CRISPR subtype II/NMENI RNA-guided endonuclease Cas9/Csn1. CRISPR loci appear to be mobile elements with a wide host range. This model represents a protein found only in CRISPR-containing species, near other CRISPR-associated proteins (cas), as part of the NMENI subtype of CRISPR/Cas locus. The species range so far for this protein is animal pathogens and commensals only.	2.17086e-103
NZ_CP048279.1\|WP_162682323.1\|2088120_2088663_-\|alkaline-shock-response-membrane-anchor-protein-AmaP	gnl\|CDD\|380217	NF033218, anchor_AmaP, alkaline shock response membrane anchor protein AmaP. The founding member of this family, AmaP (Asp23 membrane anchoring protein), is related to Asp23 through part of its length, but includes a highly hydrophobic N-terminal region that should make it an integral membrane protein. Asp23 (alkaline shock protein of 23 kDa), described in PMID:7864904, is a cytosolic protein in Staphylococcus aureus, strongly induced by a pH shift from 7 to 10, and also recruited to the membrane. AmaP appears to be the partner protein with an integral membrane segment and the ability to anchor Asp23 to the membrane. This model was built to identify full-length homologs of AmaP, while excluding Asp23. Some but not all members of this family score above the cutoffs of Pfam model version PF03780.11, but full-length homologs of Asp23 score considerably higher. Asp23 family members previously were known as DUF322.	2.18271e-33
NZ_CP048279.1\|WP_162682329.1\|2098950_2100171_-\|carboxylesterase-family-protein	gnl\|CDD\|225181	COG2272, PnbA, Carboxylesterase type B [Lipid metabolism].	8.99844e-49
NZ_CP048279.1\|WP_162682332.1\|2102063_2103467_-\|6-phospho-beta-galactosidase	gnl\|CDD\|184102	PRK13511, PRK13511, 6-phospho-beta-galactosidase; Provisional.	0
NZ_CP048279.1\|WP_162682321.1\|2086026_2087172_+\|MFS-transporter	gnl\|CDD\|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	1.8331e-73
NZ_CP048279.1\|WP_162682327.1\|2093826_2094702_-\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	1.3526e-92

>NZ_CP048279.1|WP_162682325.1|2090516_2091527_-|zinc-binding-alcohol-dehydrogenase-family-protein
MEAIIARQPFQLAEGQKFEKVSRELPTPEAHDILVKVHATGVNPVDTKMRQALLNADARVLGFDAAGVVEVVGDAVTDFKPGDRVYYSGSNQRDGSNQTYQLVNENYLALMPETLSFAEAAALPLTAITAYETLFDVFNISPKPQENQGKTLFIINGAGGVGSIVTQIAKAYGLTVITTASRPETRAWSEKMGADIVLNHQEDLAKQFDDQNLSCPNYIFCTYDTDYYYDVMIDLVQPRGHIATIVAFNQDQDLNALKQKSITFTHEFMFARAIHGVDEWMYRKYLEDVTTKVDSGQYQTTLNSVLSGLTPENVFKAHEMMEAQSHIGKLVIEIVE
>NZ_CP048279.1|WP_162682324.1|2088945_2090460_-|BCCT-family-transporter
MKQTEKKKHVSVVFWISLLLCSLFVLVGAIFPKQMEQTTQSITTWIGQNFSWYYLLLLLAIFLVCIYLLFSRYSQITLGEEGEEPEFSLKSWFAMLFSAGMGIGLVFWTTAEPISHAYTATPIHQAGTQAAIDDSLQFAFFHWGIHAWAVYAIVALAFAYFNFHKGYPGLVSATLTPLFGEKRMQGLLGKLLDILAIIATVTGVSATLGFGALQISEGLNFLFNIPANFTTQILIIIIATALFIWSTWSGLSKGIKMLSNINMILAFVVLVVVFIIGPTLYILNMFTNSLGNYIAHFFDMSLRLTINNPEKTQWIQNWTVFYWAWWISWAPFVGIFIARVSRGRTIKEFIVGVLFVPSFVCFIFFAVFGASAIYLQDNGIANNAGEAIETATFATLEHFPFGFVMSIVTLVVVMIFFVTSADSATYVLGMLSTNGDNYPGSWVKVSWGIMLALFALIMLLTGGTQAIQNLLIIAALPFSFVIIFMVWSLFKALAAERPRLSKRK
>NZ_CP048279.1|WP_162682323.1|2088120_2088663_-|alkaline-shock-response-membrane-anchor-protein-AmaP
MTRIKNFILGLLIVIIVGFLLFMYIDYKPIKSYQDYFYQFNWFYPLLIGLAAFLVLIGLILFFRAFKPTYRKPGLYKDYKDGHIYISRKSIENTVYDTIAKYDAIRQPNVVSKLYNKKNNSFIDITTDFLVPSEATNVQSLVEQLRVDIKENVERFSELHVKTVKVNVRDQKRDNGPRVV
>NZ_CP048279.1|WP_019165072.1|2087862_2088108_-|DUF2273-domain-containing-protein
MSNENRNGQSERDSVEQFAKILQNYKWRIIGFFFFLIIAILFLTLGFWKTILIIVLCLIGIGVGYIKDRTQDFLNLLNRLS
>NZ_CP048279.1|WP_162682322.1|2087316_2087808_-|Asp23/Gls24-family-envelope-stress-response-protein
MAVENNKAKENYNKETGVNERERQQSQENQGPQFSNSLTFSDEVVEKIAGIAAREVRGILDMKGGFVDSISGSFNGGNNVTQGVSAEVGEKQAAIDLKVILEYGESAPKIFRKVTELIKEQVKHITGLDVVEVNMQVDDVMTRKEWQQKNEKNRDQNENKGLQ
>NZ_CP048279.1|WP_162682321.1|2086026_2087172_+|MFS-transporter
MTIMRTLTFMLSIFIVGMVEMVVAGIMNLMSTDLNISEAWIGQLVTIYAFTFALTGPILVKLTEKYSPKSVLLSAIAFFVIGNLMIALSPNFTILIIGRIISSAAAALIVVKILSTTVVLARPENRGKMLGIVYTGFSASNVFGVPIGTLIGDWAGWRFTFGLIILVGLIAGVLLTVYLPKEVKSSPQTTRNRTSRILDKGEVTKLLSITFILLTANSVAYIYINPLILSGGHNIQFVSLALLIIGIAGMLGTSMGGFFTDKLSFKTWLLVSGGAFVIVMLVLNQLWTASTILLIALFIWHIIQWSTNPAVQSGLIDQVEGDNSQVMSWNMSALNAGIGFGALLGGLIVSHIDLHATIYFAAGMGFIGFIIILMLKKKRVA
>NZ_CP048279.1|WP_162682320.1|2083948_2085916_+|sialic-acid-synthase
MKTEQNHLSMIEKDFTKDEMENYQTVLQFDSNWATQFKRHILVGRDKITARLVASLYRENLVGSYTNSTFVQAEQLEHSAISSGELLMIHFTYGPLTLYARVIGHHAFNRVDVTGPFYWRTPDGEDRRVLHPNEVLDVIINEDTQYQGAAAEQFRDDMENSAAHMTLALSYQALHPLKDASSLLDYIEAQDDPYLTSEQLVVEGHPLHPGAKLRKGMSAQETIDYSSEYQHTMPMQFILLHRDVARTMVQQGTYAEVVYHAFDGLKSVAQQAIGTHAKLEDYMPLIVHPWQYEHIIRTEYQHELDTKAIIPLDYTKSYYAGLSFRTLMPKKPDVSPHIKLSTNVHITGEIRTLSEQTTHNGPLMTNILTAISAQDTLFNNVPTSPVPEIAGAHFYLSKDSQPDEQEQRSEQLGTLFRQNIYDMIDSDSLPLIPSSLVVTHPETTRPLIVELVERFGQSSKDTTDIDTRAQWFKAYAASLIDYVVPLLVKYGIALEAHLQNTIAIFEPSTGAFSHMLIRDFEGLRIDAEQLAQMGYDTAHFHEKSRILTKSQTSVFNKAFYSTIQNHLGELVAALARFYNDAALENTLWSIVRQQIEQCFAKLEAADIDPQRLAHMQDIFFNETIDYKCVTTMRLLDKAHEYTYVKVDNPLSKLII
>NZ_CP048279.1|WP_162682319.1|2082663_2083848_-|MFS-transporter
MAKWFFPSTFLLFLGNWIGQIALNWYAYQLNENPMDLALINFFRLAPIFILSLWAGSFADRYRRSTLIKMTVTSSMVITGTLTVCVLFMNEIPMLYLYIYACLRGCMSAVETPVRQAVLPDISERLTVSKAVSYHSFLLNVCRSIGPAVAGFIIAAYDVPIAFVVQTICYALALVSSIPLKLAVVKPVKNKQFSLAVVMQYFKLHLQGRRIFMTSLLIMAMGYSYTTMLPILTDEVYPNSASVFGTAMTVSAIGGVLATLTIPYVLQKFSTDNCYYLSSILFGIALLLLYPLGEIGLFLMIFFVGLFGQFARTTNRIYFQNDVEQESRGKILSVIMMDRGMIPFGAMLLSYFTELIGITTTFLVMGGATTIIAILGFLTNFKMNGGKTVHDTQP
>NZ_CP048279.1|WP_162682318.1|2080910_2082680_-|siderophore-synthetase
MTLNHKLNADQNIQYRMLIACMKEQLFPEKTQLQYKQKQVVIQYHQHVLTVQYETISTLYQLELSGPIVYRVGTEDVTIETVEQLIEVLGAHFGITFHNQLVEELLHSRLGLELSYQQLRQRERVMRHSLKFSRMPDTLNFIAWLNHMNGDELFSVLGYTEGMVWEGHPSHPLTKTKLPLNTNEIQQYAPEFMKIIPLKIVLVRKDLLKSTTMTGEEDFVLRKMFPDKKSQLRQWMQMYEGTLDDYRIMLVHPWQYTNVITARFKIMIAQHDVIPTPFTVDSKATLSFRTMRLLQYPYHVKLPVNVQATSAVRTVSTVTTVDGPKLSYQLQDMLDIYPTLSVASEPYGAHIDVEADLARQFAMIVRHSPEVEVHRHEDTQLVTAVLTQVNPVDGQVVVDSLIEYLYGEINTQTIQQFMRQYMEALIPPLIAYIQQYGIALEAHQQNTILQIDKENETLSFIVRDLGGSRIYPETLKQTVPDFEITNDSLVSDEIEAVIAKFQHAVIQNQLGTLIHHFHHVHQIDEMTLYAIAADEIEAAIDPTRAHAAALKRILFGDKMTVKALLNMRMKQKVKQYVQIDIKNPLEREL
>NZ_CP048279.1|WP_162682317.1|2079830_2080907_-|alanine-racemase
MPQIHINLSKIKYNAMVLQCMLAEQGVRMIPVTKCMGGDTKVHQQFREMGFNTLAESRLTTMMSGEQQPSKQDMMIKGALPHEINDVVRYSQISIQTELETICALSDEAVAQGVKHHIYLMVDWKDGREGALTYEVVPLIKEIIRLKGVYLKGLSFNFMCFRQIPPTEEDIVYINYFIESVERDTGMKFKTISGGNSSMLTLAMYADLGRINELRIGEALFRGYETAYNMRLPYLFDNAVTLSGRILEIKPRLNLETRQSYMQALVDIGQLDTVISGIQPVDRQLKIVGHSSDTLMMNLGLADYYQIGDKIEFHLDYAALAHSMHMRHIPKSYDEDLGIEQLVSGFVDIKKNNFIKQY
>NZ_CP048279.1|WP_162682326.1|2092609_2093458_-|hypothetical-protein
MKIASHVTEVLEIKEESVNIITFEDTALCGTFIQDFMDYMTNKPVVENQFAHFISDDYETISPKNFHPIILNCGDRNLLGQKLIEEKVYQIFEEQIINYEKANHSFLKFEQSLIDLKNTLGIYDDDYQIELQPSIFKLRRLLKLFGLDFHNELEDLSEINKRKAFIDLLIHSTKENILIVLFPESHLGIRDIEVFMQLLKKYHFTTIVFTNHPSIIINEENIFLCKSNKECHDIEKIKEELSLFIPDEMVSYQLTHMIAYHEFVGENLSEFKRYFKFINHYN
>NZ_CP048279.1|WP_162683043.1|2093454_2093748_-|CRISPR-associated-endonuclease-Cas2
MFDLPVETSSERRAYRQFVKFLTNEGYVRLQFSIYCKLIFNSSTLNHQITKLKSVVPSNGIVQALVVTENQFSNMKYLVGTPPKGQIGLSSERVIEL
>NZ_CP048279.1|WP_162682327.1|2093826_2094702_-|type-II-CRISPR-associated-endonuclease-Cas1
MSFRTVIITKESKLSLRMNQLIVKGENLSRIPLNEILCLVIEHPNVSMTGHLMNALSDQKIVTILCNTKHLPNTVLLPLYGHHRQVRLIQNQISWKSERKAELWQLLVKYKILNQKQVVQEFFKESSTDLFDAFVNSVELDDSTNREGHAAKVYFNIILDHGHARGDDTAQNAAMDYGYQVLLAIVARTIVSKGYLTELGIKHRNEFNIYNLASDFMEIFRPLIDYLVLKNVEQQFETDQKRAILNILNRRLIVDNKRYFFLNAVEIYVDSLFKYLSSGDIEVIKIPTWTY
>NZ_CP048279.1|WP_162682328.1|2094691_2098696_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MAQKPYILSLDIGTGSVGYACMDKEFNILKYYDKDAIGVYLFDGALTAQERRQFRTARRRNNRRIKRLGLLQEILAPLVQNPNFYQFQRQFTWKNDNMDFKNKSLSEVLSFLRYAPKKYPTIYHLQEALLLKDEKFEPELIYIALYHLVKYRGHFLFNYLNIENLSNNDNMEDFVELIEVYEKLNNISLNLDYEKKKEIFDILQDNEMTKNDREKAVVKIEKELKQFSKMLLGLKFNEGDLFNHADNAEELKEAKQSHSFADNYEENLTSFLTVEQLELIERANKIYLSFTLQDILNGNKSMAISKVAAYDKFKNELKQVKDIVYKADPTKVQFKKIFVSSKESLKQYEAIPNDENFSALCLFDQYVIRPKKQYSSFIKELKKIIPQDSELYFEAENDTLLKVLNTTDNASIPMQISLYEAETILRNQQKYHAEITDEIIEKVLSLIQFRIPYYVGPLVNDQATAKFGWMERKSNEPIKPWNFDEVVDRSKSATQFIRRMTNKCTYLMNEDVLPKNSLLYQEMELLNELNAIQVRFQTDPKNRKYRLIPQIKLFAVEHIFKKYKTVSHSKFLEIMLNSNHRENFMNHGERLSIFGTQDDKKFVSKLSSYQDMTKIFGNIDDKRAQIEEIIQWITIFEDKKILVQKLKENYPELTSQQINQLKKLNYSGWGRLSEKLLTHSHQGHSIIELLRHSDENFMEILTNDDYGFQNFIKEENQVQSNTIQYQDIANLATSPALKKGIWSTIKLVRELTSIFGEPEKIIMEFATEDQQKGKKQKSRKQLWDDNVKKNKLKSVDEYKYIIDVANKLNNEQLQQEKLWLYLSQNGKCMYSGKSIDLDTLLSSNATKYYEVDHIIPRSFIKDDSIDNKVLVIKAMNQTKGDQVPLQFIHHPYERIAYWKSLNKAGLISDSKLHKLMKPEFNAMDKEGFIQRQLVETRQISVHVRDFLKEEYPDAKVIPMKAKMVTEFRKKFDIPKIRQMNDAHHAIDAYLNGVVYHGAQLAYPNVDLFDFNFKWEKVREKWKALGEFNTKQKTRELFFFKKLEKMEVSQGERLISKIKLDMNHFKINYSKKLANIPQQFYKQTALSPKTAELKYESDKSTDAVYSSLTTYQTFVVAIKTATKKGKVKMQYQMIDHYVFDFYKFKNGNEKELALYLARRENKEEVLDAHIVYSLNKGDLLYINNHPCYFVSSNEVINAKQFELTVEKQLSLYNALNNKETSVEELVNVYDDIAEKVTNEYRHYLNSALKEERVKTLFSQSNQSHEDFVKALDELFKVVKASAVRSEKIGSRKNSMSNRAFLGKGRDVKIAYTSISGLKTTKPKSLFKLAESRNEL
>NZ_CP048279.1|WP_162682329.1|2098950_2100171_-|carboxylesterase-family-protein
MAKMMQIHDKQIKVCAFNQSYAAFQIPYAQNEGRLQYSSLLKWEDLDTVIDCSMRGRVFPQNPNRLSTVMGCRQEEKNQSEAAFHLNIFSSKQFKNKPVLFWIHGGGWLTGGGALPWYDGNHLAENEDIVVVTINYRIGALGAFQTEEGPKNLGLNDIINALTWVHNNIYYFGGDSDNITVGGQSAGAWYTAALLGHVDAHHLFNKAILASFPGQIKPLTALSSQQLSTQLQNYLAPKTMATATTQEILDAQNQVMTHLSHHQPSRIPTSFIPIESEQLSKDLIDQAVKVSGGNKDVMAWVTQNEMNAFKPHGNIADELDKMRVEEFEQPTKALLQQFEDKGSDVHFQIIDGGNDRLGAPHCFDLPLLFGNFEQWSNAPMLEGTKDQKLKAASRQLQQHVAQFMRA
>NZ_CP048279.1|WP_162682330.1|2100189_2101398_-|MFS-transporter
MESTQGSKIWTKEFVVNFIINFLVFLCMYLLMVVMARYTIQTFDTTDSIGGLVAGLFVIGSLLGRFMTGRFVDNVGPRKLLVVGSILLLITQALYFVEGSLMLLIIVRILNGMATAVVTTATGAVAGYLTPENRKGEGIAMFGLSLIVGAAIGPFFGLYLSEHYPMEVIFTLCIVIGVISFASVFFLNVEFPQAEQPVHATHQKFSIHKYFAVEAVPVGIVTLLIAVGYSSLLSFIQFFATENHFESISSYYFIVYAIAALVTRPIAGQLMDEYNENVVNIPAFISFALSLFLLGITQNPIAFFVSAILAGIGYGNLASTLQAVAVKVVPFHKIGLATATFFIGLDVGLGFGPFVLGMFTAKIGFANIYICMGVLLVLTLIFYYFVHGKRMKNIYGKQLSQH
>NZ_CP048279.1|WP_162682331.1|2101405_2101825_-|MarR-family-transcriptional-regulator
MNDFFSLTLSLYRPYVKKIEPILNEHSLNLARWLVLKDIGYHQPTALVEIAKRRFIEKSTTHQILKVFEEKQLIVVTTDKNDKRHKWIELSKEGQVLFQSINKRILEMDDKILSEVKNDENFEHICQFMEQLLNRMKGS
>NZ_CP048279.1|WP_162682332.1|2102063_2103467_-|6-phospho-beta-galactosidase
MKKLPKDFIFGGATAAYQAEGATNIDGKGRVAWDTYLEENYWYTAEPASDFYHRYPVDLELSEKFGVNGIRISIAWSRIFPTGYGEVNPQGVDYYHRLFKECIKRNVEPFVTLHHFDTPETLHSNGDFLNRDNIQHFVDYAEFCFNEFKEVNYWTTFNEIGPIGDGQYLVGKFPPGIQYHFEKVFQSHHNMMVAHAKAVVLFKEQGHQGEIGVVHALPTKYPFNPDNPEDVRAAELEDILHNKFILDATYLGHYSEKTMEGVNHILSVNGGKLDLREEDFEILEAAKDLNDFLGINYYMSDWMRGFEGESEITHNSKGDKGGSKYQLKGVGQREFDVDVPRTDWDWMIYPQGLYDQIMRVKNDYPNYKKIYITENGLGYKDDFVDNTVQDDARIDYVKQHLEVIADTIEDGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERYPKKSAYWYKKLAETQIIE
>NZ_CP048279.1|WP_162682333.1|2103484_2105218_-|PTS-transporter-subunit-EIIC
MNKLIGLIEKGKPFFEKLSRNIYLRAIRDGFISAMPIILFSSIFLLIAYVPNIFGFKWSKEMEALIMKPYGYTMGIVGLFVAGTTAKALTDSFNRKLERTNQINFISTMLASMSGFLFLASNALEEGGFANAFMGTKGLLTAFLSAFITVFIYNICIKNNITIKMPKEVPPNISQVFKDLIPFSLVILILYGLDILSRSVNKTNVAESILKTFEPLFTAADGYVGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANIETNFKLLHAGEHADKILTPGTQMFIVTMGGTGATLVVPFIFMWLSKSKRNKAIGRASVVPTFFGVNEPILFGAPIVLNPIFFIPFIAAPIINVWIFKFFVDVIGMNSFSVFLPWTTPGPLGIVMGTGFEVWAFVLAITLIIVDVIVYYPFFKVYDNQILEDELKGVDSTNELHAKVGENFNTKKAEAILGSTANKSTDQAVKEDKDSSAVSDITGPTNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAADSYGAHMDIMKDFDLVILAPQVASNYQDIKRDTDRLGIKLAKTQGVEYINLTRDGQAALKFVQDQFK
>NZ_CP048279.1|WP_096555582.1|2105223_2105538_-|PTS-lactose/cellobiose-transporter-subunit-IIA
MNREEVTMLGFEIVAYAGDARSKYLEALSAARDGDYDKAEQLIEEGNQCIVDAHKAQTSLLQKEAIGDDIAYSVTMMHGQDHLMTTILLKDMLKHIIELYKRGS

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP048279_2	2.7\|2092027\|30\|NZ_CP048279\|CRT,CRISPRCasFinder	2092027-2092056	30	MK075005	Staphylococcus phage phiSP119-2, partial genome	4795-4824	3	0.9
NZ_CP048279_2	2.9\|2092159\|30\|NZ_CP048279\|CRT,CRISPRCasFinder,PILER-CR	2092159-2092188	30	MK075005	Staphylococcus phage phiSP119-2, partial genome	4795-4824	3	0.9
NZ_CP048279_1	1.2\|140156\|33\|NZ_CP048279\|PILER-CR,CRISPRCasFinder,CRT	140156-140188	33	NZ_CP013752	Lactobacillus plantarum strain KP plasmid unnamed3, complete sequence	65038-65070	4	0.879
NZ_CP048279_2	2.2\|2091897\|28\|NZ_CP048279\|PILER-CR	2091897-2091924	28	KC821607	Cellulophaga phage phi19:1, complete genome	7895-7922	6	0.786
NZ_CP048279_2	2.3\|2091963\|30\|NZ_CP048279\|PILER-CR	2091963-2091992	30	KC413988	Streptococcus phage phiST1, complete genome	12576-12605	6	0.8
NZ_CP048279_2	2.11\|2092290\|29\|NZ_CP048279\|CRT,CRISPRCasFinder,PILER-CR	2092290-2092318	29	MN855764	Siphoviridae sp. isolate 508, partial genome	48364-48392	6	0.793
NZ_CP048279_2	2.12\|2092355\|30\|NZ_CP048279\|CRT,CRISPRCasFinder,PILER-CR	2092355-2092384	30	NC_019782	Lactobacillus phage AQ113, complete genome	30602-30631	6	0.8
NZ_CP048279_1	1.2\|140156\|33\|NZ_CP048279\|PILER-CR,CRISPRCasFinder,CRT	140156-140188	33	NZ_CP009068	Borreliella afzelii K78 plasmid cp32-9, complete sequence	30062-30094	7	0.788
NZ_CP048279_1	1.2\|140156\|33\|NZ_CP048279\|PILER-CR,CRISPRCasFinder,CRT	140156-140188	33	NZ_CP015328	Bacillus filamentosus strain Hbe603 plasmid pBEH6, complete sequence	7405-7437	7	0.788
NZ_CP048279_1	1.2\|140156\|33\|NZ_CP048279\|PILER-CR,CRISPRCasFinder,CRT	140156-140188	33	MN693111	Marine virus AFVG_25M354, complete genome	16918-16950	7	0.788
NZ_CP048279_1	1.2\|140156\|33\|NZ_CP048279\|PILER-CR,CRISPRCasFinder,CRT	140156-140188	33	NZ_CP019921	Borreliella burgdorferi strain PAbe plasmid p_cp32-9-4, complete sequence	59753-59785	7	0.788
NZ_CP048279_1	1.2\|140156\|33\|NZ_CP048279\|PILER-CR,CRISPRCasFinder,CRT	140156-140188	33	NC_017423	Borreliella burgdorferi N40 plasmid N40_cp32-12, complete sequence	26563-26595	7	0.788
NZ_CP048279_1	1.2\|140156\|33\|NZ_CP048279\|PILER-CR,CRISPRCasFinder,CRT	140156-140188	33	NZ_CP019848	Borreliella burgdorferi plasmid cp32-4, complete sequence	29095-29127	7	0.788
NZ_CP048279_1	1.2\|140156\|33\|NZ_CP048279\|PILER-CR,CRISPRCasFinder,CRT	140156-140188	33	NZ_CP019759	Borreliella burgdorferi strain B31_NRZ isolate B31 plasmid p_cp32-4, complete sequence	29096-29128	7	0.788
NZ_CP048279_1	1.2\|140156\|33\|NZ_CP048279\|PILER-CR,CRISPRCasFinder,CRT	140156-140188	33	MN855959	Siphoviridae sp. isolate 167, complete genome	6312-6344	7	0.788
NZ_CP048279_2	2.3\|2091963\|30\|NZ_CP048279\|PILER-CR	2091963-2091992	30	LR877331	Klebsiella phage vB_KpnM_311F genome assembly, chromosome: 1	75853-75882	7	0.767
NZ_CP048279_2	2.3\|2091963\|30\|NZ_CP048279\|PILER-CR	2091963-2091992	30	NC_031095	Klebsiella phage PKO111, complete genome	123151-123180	7	0.767
NZ_CP048279_2	2.3\|2091963\|30\|NZ_CP048279\|PILER-CR	2091963-2091992	30	MN101230	Klebsiella phage KPN6, complete genome	57380-57409	7	0.767
NZ_CP048279_2	2.3\|2091963\|30\|NZ_CP048279\|PILER-CR	2091963-2091992	30	CP015514	Vibrio vulnificus strain FORC_036 plasmid unnamed, complete sequence	288860-288889	7	0.767
NZ_CP048279_2	2.5\|2091895\|29\|NZ_CP048279\|CRT,CRISPRCasFinder	2091895-2091923	29	KC821607	Cellulophaga phage phi19:1, complete genome	7894-7922	7	0.759
NZ_CP048279_2	2.6\|2091960\|31\|NZ_CP048279\|CRT,CRISPRCasFinder	2091960-2091990	31	MN101230	Klebsiella phage KPN6, complete genome	57380-57410	7	0.774
NZ_CP048279_2	2.6\|2091960\|31\|NZ_CP048279\|CRT,CRISPRCasFinder	2091960-2091990	31	LR877331	Klebsiella phage vB_KpnM_311F genome assembly, chromosome: 1	75852-75882	7	0.774
NZ_CP048279_2	2.6\|2091960\|31\|NZ_CP048279\|CRT,CRISPRCasFinder	2091960-2091990	31	NC_031095	Klebsiella phage PKO111, complete genome	123150-123180	7	0.774
NZ_CP048279_1	1.2\|140156\|33\|NZ_CP048279\|PILER-CR,CRISPRCasFinder,CRT	140156-140188	33	NZ_AP019717	Clostridium butyricum strain NBRC 13949 plasmid pCBU1, complete sequence	249692-249724	8	0.758
NZ_CP048279_1	1.2\|140156\|33\|NZ_CP048279\|PILER-CR,CRISPRCasFinder,CRT	140156-140188	33	NC_011995	Macrococcus caseolyticus JCSC5402 plasmid pMCCL1, complete sequence	4176-4208	8	0.758
NZ_CP048279_1	1.2\|140156\|33\|NZ_CP048279\|PILER-CR,CRISPRCasFinder,CRT	140156-140188	33	NC_014533	Gloeothece verrucosa PCC 7822 plasmid Cy782201, complete sequence	639984-640016	8	0.758
NZ_CP048279_1	1.2\|140156\|33\|NZ_CP048279\|PILER-CR,CRISPRCasFinder,CRT	140156-140188	33	NZ_CP034857	Buchnera aphidicola (Sitobion avenae) strain Sav plasmid pTrp, complete sequence	2831-2863	8	0.758
NZ_CP048279_2	2.3\|2091963\|30\|NZ_CP048279\|PILER-CR	2091963-2091992	30	AP011616	Thermus phage phiYS40 DNA, complete genome	35394-35423	8	0.733
NZ_CP048279_2	2.3\|2091963\|30\|NZ_CP048279\|PILER-CR	2091963-2091992	30	DQ997624	Thermus thermophilus phage YS40, complete genome	35394-35423	8	0.733
NZ_CP048279_2	2.3\|2091963\|30\|NZ_CP048279\|PILER-CR	2091963-2091992	30	NC_008584	Thermus phage phiYS40, complete genome	35394-35423	8	0.733
NZ_CP048279_2	2.3\|2091963\|30\|NZ_CP048279\|PILER-CR	2091963-2091992	30	NZ_CP049807	Acinetobacter pittii strain A1254 plasmid pA1254_1, complete sequence	34026-34055	8	0.733
NZ_CP048279_2	2.7\|2092027\|30\|NZ_CP048279\|CRT,CRISPRCasFinder	2092027-2092056	30	LR700236	marine metagenome genome assembly, complete genome: monopartite	5723-5752	8	0.733
NZ_CP048279_2	2.9\|2092159\|30\|NZ_CP048279\|CRT,CRISPRCasFinder,PILER-CR	2092159-2092188	30	LR700236	marine metagenome genome assembly, complete genome: monopartite	5723-5752	8	0.733
NZ_CP048279_2	2.11\|2092290\|29\|NZ_CP048279\|CRT,CRISPRCasFinder,PILER-CR	2092290-2092318	29	LC553736	Salmonella phage SAP012 DNA, complete sequence	17575-17603	8	0.724
NZ_CP048279_2	2.11\|2092290\|29\|NZ_CP048279\|CRT,CRISPRCasFinder,PILER-CR	2092290-2092318	29	MN694452	Marine virus AFVG_250M839, complete genome	32448-32476	8	0.724
NZ_CP048279_2	2.12\|2092355\|30\|NZ_CP048279\|CRT,CRISPRCasFinder,PILER-CR	2092355-2092384	30	NZ_CP017986	Klebsiella pneumoniae strain 825795-1 plasmid unnamed1, complete sequence	54093-54122	8	0.733
NZ_CP048279_2	2.12\|2092355\|30\|NZ_CP048279\|CRT,CRISPRCasFinder,PILER-CR	2092355-2092384	30	NZ_CP018714	Klebsiella pneumoniae strain Kp_Goe_152021 plasmid pKp_Goe_021-1, complete sequence	160013-160042	8	0.733
NZ_CP048279_2	2.12\|2092355\|30\|NZ_CP048279\|CRT,CRISPRCasFinder,PILER-CR	2092355-2092384	30	NZ_CP018720	Klebsiella pneumoniae strain KP_Goe_828304 plasmid pKp_Goe_304-1, complete sequence	120021-120050	8	0.733
NZ_CP048279_2	2.12\|2092355\|30\|NZ_CP048279\|CRT,CRISPRCasFinder,PILER-CR	2092355-2092384	30	NZ_CP018702	Klebsiella pneumoniae strain Kp_Goe_827024 plasmid pKp_Goe_024-1, complete sequence	100464-100493	8	0.733
NZ_CP048279_2	2.12\|2092355\|30\|NZ_CP048279\|CRT,CRISPRCasFinder,PILER-CR	2092355-2092384	30	NZ_CP042866	Escherichia coli strain ATCC BAA-196 plasmid unnamed1, complete sequence	50482-50511	8	0.733
NZ_CP048279_2	2.12\|2092355\|30\|NZ_CP048279\|CRT,CRISPRCasFinder,PILER-CR	2092355-2092384	30	NZ_CP018313	Klebsiella pneumoniae strain Kp_Goe_822579 plasmid pKp_Goe_579-1, complete sequence	342-371	8	0.733
NZ_CP048279_2	2.12\|2092355\|30\|NZ_CP048279\|CRT,CRISPRCasFinder,PILER-CR	2092355-2092384	30	NZ_CP018687	Klebsiella pneumoniae strain Kp_Goe_149473 plasmid pKp_Goe_473-1, complete sequence	22235-22264	8	0.733
NZ_CP048279_2	2.12\|2092355\|30\|NZ_CP048279\|CRT,CRISPRCasFinder,PILER-CR	2092355-2092384	30	NZ_CP034054	Klebsiella pneumoniae strain KP_NORM_BLD_2015_112126 plasmid unnamed1, complete sequence	257391-257420	8	0.733
NZ_CP048279_2	2.12\|2092355\|30\|NZ_CP048279\|CRT,CRISPRCasFinder,PILER-CR	2092355-2092384	30	NZ_CP018696	Klebsiella pneumoniae strain Kp_Goe_149832 plasmid pKp_Goe_832-1, complete sequence	197601-197630	8	0.733
NZ_CP048279_2	2.12\|2092355\|30\|NZ_CP048279\|CRT,CRISPRCasFinder,PILER-CR	2092355-2092384	30	NZ_CP018708	Klebsiella pneumoniae strain Kp_Goe_827026 plasmid pKp_Goe_026-1, complete sequence	150119-150148	8	0.733
NZ_CP048279_1	1.2\|140156\|33\|NZ_CP048279\|PILER-CR,CRISPRCasFinder,CRT	140156-140188	33	NZ_CP007513	Bacillus bombysepticus plasmid pBb, complete genome	428798-428830	9	0.727
NZ_CP048279_1	1.2\|140156\|33\|NZ_CP048279\|PILER-CR,CRISPRCasFinder,CRT	140156-140188	33	NZ_CP050184	Bacillus thuringiensis strain HER1410 plasmid pLUSID1, complete sequence	96866-96898	9	0.727
NZ_CP048279_1	1.2\|140156\|33\|NZ_CP048279\|PILER-CR,CRISPRCasFinder,CRT	140156-140188	33	NZ_CP033050	Virgibacillus halodenitrificans strain Bac324 plasmid unnamed, complete sequence	298880-298912	9	0.727
NZ_CP048279_2	2.3\|2091963\|30\|NZ_CP048279\|PILER-CR	2091963-2091992	30	NC_048697	Pseudomonas phage Littlefix, complete genome	19802-19831	9	0.7
NZ_CP048279_2	2.6\|2091960\|31\|NZ_CP048279\|CRT,CRISPRCasFinder	2091960-2091990	31	AP011616	Thermus phage phiYS40 DNA, complete genome	35393-35423	9	0.71
NZ_CP048279_2	2.6\|2091960\|31\|NZ_CP048279\|CRT,CRISPRCasFinder	2091960-2091990	31	DQ997624	Thermus thermophilus phage YS40, complete genome	35393-35423	9	0.71
NZ_CP048279_2	2.6\|2091960\|31\|NZ_CP048279\|CRT,CRISPRCasFinder	2091960-2091990	31	NC_008584	Thermus phage phiYS40, complete genome	35393-35423	9	0.71
NZ_CP048279_2	2.6\|2091960\|31\|NZ_CP048279\|CRT,CRISPRCasFinder	2091960-2091990	31	NZ_CP049807	Acinetobacter pittii strain A1254 plasmid pA1254_1, complete sequence	34026-34056	9	0.71

1. spacer 2.7|2092027|30|NZ_CP048279|CRT,CRISPRCasFinder matches to MK075005 (Staphylococcus phage phiSP119-2, partial genome) position: , mismatch: 3, identity: 0.9

aatgctccaaaagcagaaagcacagattcg	CRISPR spacer
aatgctccaaaagcagaaaactcagattct	Protospacer
*******************.* *******

2. spacer 2.9|2092159|30|NZ_CP048279|CRT,CRISPRCasFinder,PILER-CR matches to MK075005 (Staphylococcus phage phiSP119-2, partial genome) position: , mismatch: 3, identity: 0.9

aatgctccaaaagcagaaagcacagattcg	CRISPR spacer
aatgctccaaaagcagaaaactcagattct	Protospacer
*******************.* *******

3. spacer 1.2|140156|33|NZ_CP048279|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013752 (Lactobacillus plantarum strain KP plasmid unnamed3, complete sequence) position: , mismatch: 4, identity: 0.879

-aattatttttttgaattctttatattttttaga	CRISPR spacer
caattcgtttttt-aattctttatatttttttga	Protospacer
 ****  ****** ***************** **

4. spacer 2.2|2091897|28|NZ_CP048279|PILER-CR matches to KC821607 (Cellulophaga phage phi19:1, complete genome) position: , mismatch: 6, identity: 0.786

cattctaatacctaaaatcgcataaata	CRISPR spacer
aaaactaacacctaaaaccgcataaatg	Protospacer
 *  ****.********.*********.

5. spacer 2.3|2091963|30|NZ_CP048279|PILER-CR matches to KC413988 (Streptococcus phage phiST1, complete genome) position: , mismatch: 6, identity: 0.8

cggttgaagatattaaagatgagctagcca	CRISPR spacer
cgtataaagatattcaagatgagctaggta	Protospacer
**  *.******** ************ .*

6. spacer 2.11|2092290|29|NZ_CP048279|CRT,CRISPRCasFinder,PILER-CR matches to MN855764 (Siphoviridae sp. isolate 508, partial genome) position: , mismatch: 6, identity: 0.793

atagcctctgcaacttctttat---gctttat	CRISPR spacer
ttagcttctgcaacttctttattaaactt---	Protospacer
 ****.****************   .***

7. spacer 2.12|2092355|30|NZ_CP048279|CRT,CRISPRCasFinder,PILER-CR matches to NC_019782 (Lactobacillus phage AQ113, complete genome) position: , mismatch: 6, identity: 0.8

taagtgtacttatagtgtgctatttcttca	CRISPR spacer
tcagaatctttatagtgagctatttcttca	Protospacer
* ** .* .******** ************

8. spacer 1.2|140156|33|NZ_CP048279|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009068 (Borreliella afzelii K78 plasmid cp32-9, complete sequence) position: , mismatch: 7, identity: 0.788

aattatttttttgaattctttatatt---ttttaga	CRISPR spacer
cattatttttttgaatgctttttattacattct---	Protospacer
 *************** **** ****   **.*

9. spacer 1.2|140156|33|NZ_CP048279|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015328 (Bacillus filamentosus strain Hbe603 plasmid pBEH6, complete sequence) position: , mismatch: 7, identity: 0.788

aatta--tttttttgaattctttatattttttaga	CRISPR spacer
--ttaacttttttaggattctttatattttttcct	Protospacer
  ***  ****** *.****************

10. spacer 1.2|140156|33|NZ_CP048279|PILER-CR,CRISPRCasFinder,CRT matches to MN693111 (Marine virus AFVG_25M354, complete genome) position: , mismatch: 7, identity: 0.788

aattatttttttgaattctttatattttttaga	CRISPR spacer
tctttcttttttggattttttatattttttaaa	Protospacer
  ** .*******.***.*************.*

11. spacer 1.2|140156|33|NZ_CP048279|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019921 (Borreliella burgdorferi strain PAbe plasmid p_cp32-9-4, complete sequence) position: , mismatch: 7, identity: 0.788

aattatttttttgaattctttatat----tttttaga	CRISPR spacer
cattatttttttgaatactttttataacatttt----	Protospacer
 *************** **** ***    ****

12. spacer 1.2|140156|33|NZ_CP048279|PILER-CR,CRISPRCasFinder,CRT matches to NC_017423 (Borreliella burgdorferi N40 plasmid N40_cp32-12, complete sequence) position: , mismatch: 7, identity: 0.788

aattatttttttgaattctttatat----tttttaga	CRISPR spacer
cattatttttttgaatactttttataacatttt----	Protospacer
 *************** **** ***    ****

13. spacer 1.2|140156|33|NZ_CP048279|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019848 (Borreliella burgdorferi plasmid cp32-4, complete sequence) position: , mismatch: 7, identity: 0.788

aattatttttttgaattctttatat----tttttaga	CRISPR spacer
cattatttttttgaatactttttataacatttt----	Protospacer
 *************** **** ***    ****

14. spacer 1.2|140156|33|NZ_CP048279|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019759 (Borreliella burgdorferi strain B31_NRZ isolate B31 plasmid p_cp32-4, complete sequence) position: , mismatch: 7, identity: 0.788

aattatttttttgaattctttatat----tttttaga	CRISPR spacer
cattatttttttgaatactttttataacatttt----	Protospacer
 *************** **** ***    ****

15. spacer 1.2|140156|33|NZ_CP048279|PILER-CR,CRISPRCasFinder,CRT matches to MN855959 (Siphoviridae sp. isolate 167, complete genome) position: , mismatch: 7, identity: 0.788

-aattatttttttgaattctttatattttttaga	CRISPR spacer
taaata-ttttttgaattctttttatttattgcg	Protospacer
 ** ** *************** ***** **. .

16. spacer 2.3|2091963|30|NZ_CP048279|PILER-CR matches to LR877331 (Klebsiella phage vB_KpnM_311F genome assembly, chromosome: 1) position: , mismatch: 7, identity: 0.767

cggttgaagatattaaagatgagctagcca	CRISPR spacer
cgtttgaagataataaagatgagcctttga	Protospacer
** ********* ***********.  . *

17. spacer 2.3|2091963|30|NZ_CP048279|PILER-CR matches to NC_031095 (Klebsiella phage PKO111, complete genome) position: , mismatch: 7, identity: 0.767

cggttgaagatattaaagatgagctagcca	CRISPR spacer
cgtttgaagataataaagatgagcctttga	Protospacer
** ********* ***********.  . *

18. spacer 2.3|2091963|30|NZ_CP048279|PILER-CR matches to MN101230 (Klebsiella phage KPN6, complete genome) position: , mismatch: 7, identity: 0.767

cggttgaagatattaaagatgagctagcca	CRISPR spacer
cgtttgaagataataaagatgagcctttga	Protospacer
** ********* ***********.  . *

19. spacer 2.3|2091963|30|NZ_CP048279|PILER-CR matches to CP015514 (Vibrio vulnificus strain FORC_036 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cggttga--agatattaaagatgagctagcca	CRISPR spacer
--atttatccgattttaaagatgagctagcct	Protospacer
  .** *   *** *****************

20. spacer 2.5|2091895|29|NZ_CP048279|CRT,CRISPRCasFinder matches to KC821607 (Cellulophaga phage phi19:1, complete genome) position: , mismatch: 7, identity: 0.759

acattctaatacctaaaatcgcataaata	CRISPR spacer
taaaactaacacctaaaaccgcataaatg	Protospacer
  *  ****.********.*********.

21. spacer 2.6|2091960|31|NZ_CP048279|CRT,CRISPRCasFinder matches to MN101230 (Klebsiella phage KPN6, complete genome) position: , mismatch: 7, identity: 0.774

acggttgaagatattaaagatgagctagcca	CRISPR spacer
acgtttgaagataataaagatgagcctttga	Protospacer
*** ********* ***********.  . *

22. spacer 2.6|2091960|31|NZ_CP048279|CRT,CRISPRCasFinder matches to LR877331 (Klebsiella phage vB_KpnM_311F genome assembly, chromosome: 1) position: , mismatch: 7, identity: 0.774

acggttgaagatattaaagatgagctagcca	CRISPR spacer
acgtttgaagataataaagatgagcctttga	Protospacer
*** ********* ***********.  . *

23. spacer 2.6|2091960|31|NZ_CP048279|CRT,CRISPRCasFinder matches to NC_031095 (Klebsiella phage PKO111, complete genome) position: , mismatch: 7, identity: 0.774

acggttgaagatattaaagatgagctagcca	CRISPR spacer
acgtttgaagataataaagatgagcctttga	Protospacer
*** ********* ***********.  . *

24. spacer 1.2|140156|33|NZ_CP048279|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP019717 (Clostridium butyricum strain NBRC 13949 plasmid pCBU1, complete sequence) position: , mismatch: 8, identity: 0.758

aattatttttttgaattctttatattttttaga	CRISPR spacer
gttttatcttttcaattctttttattttttagt	Protospacer
. **  *.**** ******** **********

25. spacer 1.2|140156|33|NZ_CP048279|PILER-CR,CRISPRCasFinder,CRT matches to NC_011995 (Macrococcus caseolyticus JCSC5402 plasmid pMCCL1, complete sequence) position: , mismatch: 8, identity: 0.758

aattatttttttgaattctttatattttttaga	CRISPR spacer
ttttatttttttaaattttttatattcataata	Protospacer
  **********.****.********. * * *

26. spacer 1.2|140156|33|NZ_CP048279|PILER-CR,CRISPRCasFinder,CRT matches to NC_014533 (Gloeothece verrucosa PCC 7822 plasmid Cy782201, complete sequence) position: , mismatch: 8, identity: 0.758

aattatttttttgaattctttatattttttaga	CRISPR spacer
agcaaattttttgaattttttaaattttttcta	Protospacer
*.. * ***********.**** *******  *

27. spacer 1.2|140156|33|NZ_CP048279|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP034857 (Buchnera aphidicola (Sitobion avenae) strain Sav plasmid pTrp, complete sequence) position: , mismatch: 8, identity: 0.758

aattatttttttgaattctttatattttttaga	CRISPR spacer
tagttcttttttgaattctttttatttcttggg	Protospacer
 * * .*************** *****.**.*.

28. spacer 2.3|2091963|30|NZ_CP048279|PILER-CR matches to AP011616 (Thermus phage phiYS40 DNA, complete genome) position: , mismatch: 8, identity: 0.733

cggttgaagatattaaagatgagctagcca	CRISPR spacer
taattgaagaaattaaagatgagctttctt	Protospacer
...******* **************  *.

29. spacer 2.3|2091963|30|NZ_CP048279|PILER-CR matches to DQ997624 (Thermus thermophilus phage YS40, complete genome) position: , mismatch: 8, identity: 0.733

cggttgaagatattaaagatgagctagcca	CRISPR spacer
taattgaagaaattaaagatgagctttctt	Protospacer
...******* **************  *.

30. spacer 2.3|2091963|30|NZ_CP048279|PILER-CR matches to NC_008584 (Thermus phage phiYS40, complete genome) position: , mismatch: 8, identity: 0.733

cggttgaagatattaaagatgagctagcca	CRISPR spacer
taattgaagaaattaaagatgagctttctt	Protospacer
...******* **************  *.

31. spacer 2.3|2091963|30|NZ_CP048279|PILER-CR matches to NZ_CP049807 (Acinetobacter pittii strain A1254 plasmid pA1254_1, complete sequence) position: , mismatch: 8, identity: 0.733

cggttgaagatattaaagatgagctagcca	CRISPR spacer
agattgaagagattaaagaagagctattac	Protospacer
 *.******* ******** ****** .

32. spacer 2.7|2092027|30|NZ_CP048279|CRT,CRISPRCasFinder matches to LR700236 (marine metagenome genome assembly, complete genome: monopartite) position: , mismatch: 8, identity: 0.733

aatgctccaaaagcagaaagcacagattcg	CRISPR spacer
gaggctcccaaagcagaaagcacattaact	Protospacer
.* ***** ***************    *

33. spacer 2.9|2092159|30|NZ_CP048279|CRT,CRISPRCasFinder,PILER-CR matches to LR700236 (marine metagenome genome assembly, complete genome: monopartite) position: , mismatch: 8, identity: 0.733

aatgctccaaaagcagaaagcacagattcg	CRISPR spacer
gaggctcccaaagcagaaagcacattaact	Protospacer
.* ***** ***************    *

34. spacer 2.11|2092290|29|NZ_CP048279|CRT,CRISPRCasFinder,PILER-CR matches to LC553736 (Salmonella phage SAP012 DNA, complete sequence) position: , mismatch: 8, identity: 0.724

atagcctctgcaacttctttatgctttat	CRISPR spacer
tgcacctctgcaacttctttatccgtttc	Protospacer
   .****************** * ** .

35. spacer 2.11|2092290|29|NZ_CP048279|CRT,CRISPRCasFinder,PILER-CR matches to MN694452 (Marine virus AFVG_250M839, complete genome) position: , mismatch: 8, identity: 0.724

atagcctctgcaacttctttatgctttat	CRISPR spacer
tccatatctgcaacttctctatactttat	Protospacer
 . .. ************.***.******

36. spacer 2.12|2092355|30|NZ_CP048279|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP017986 (Klebsiella pneumoniae strain 825795-1 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

taagtgtacttatagtgtgctatttcttca	CRISPR spacer
ccaccccactaatagtctgctatttcttca	Protospacer
. * . .*** ***** *************

37. spacer 2.12|2092355|30|NZ_CP048279|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP018714 (Klebsiella pneumoniae strain Kp_Goe_152021 plasmid pKp_Goe_021-1, complete sequence) position: , mismatch: 8, identity: 0.733

taagtgtacttatagtgtgctatttcttca	CRISPR spacer
ccaccccactaatagtctgctatttcttca	Protospacer
. * . .*** ***** *************

38. spacer 2.12|2092355|30|NZ_CP048279|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP018720 (Klebsiella pneumoniae strain KP_Goe_828304 plasmid pKp_Goe_304-1, complete sequence) position: , mismatch: 8, identity: 0.733

taagtgtacttatagtgtgctatttcttca	CRISPR spacer
ccaccccactaatagtctgctatttcttca	Protospacer
. * . .*** ***** *************

39. spacer 2.12|2092355|30|NZ_CP048279|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP018702 (Klebsiella pneumoniae strain Kp_Goe_827024 plasmid pKp_Goe_024-1, complete sequence) position: , mismatch: 8, identity: 0.733

taagtgtacttatagtgtgctatttcttca	CRISPR spacer
ccaccccactaatagtctgctatttcttca	Protospacer
. * . .*** ***** *************

40. spacer 2.12|2092355|30|NZ_CP048279|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP042866 (Escherichia coli strain ATCC BAA-196 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

taagtgtacttatagtgtgctatttcttca	CRISPR spacer
ccaccccactaatagtctgctatttcttca	Protospacer
. * . .*** ***** *************

41. spacer 2.12|2092355|30|NZ_CP048279|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP018313 (Klebsiella pneumoniae strain Kp_Goe_822579 plasmid pKp_Goe_579-1, complete sequence) position: , mismatch: 8, identity: 0.733

taagtgtacttatagtgtgctatttcttca	CRISPR spacer
ccaccccactaatagtctgctatttcttca	Protospacer
. * . .*** ***** *************

42. spacer 2.12|2092355|30|NZ_CP048279|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP018687 (Klebsiella pneumoniae strain Kp_Goe_149473 plasmid pKp_Goe_473-1, complete sequence) position: , mismatch: 8, identity: 0.733

taagtgtacttatagtgtgctatttcttca	CRISPR spacer
ccaccccactaatagtctgctatttcttca	Protospacer
. * . .*** ***** *************

43. spacer 2.12|2092355|30|NZ_CP048279|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP034054 (Klebsiella pneumoniae strain KP_NORM_BLD_2015_112126 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

taagtgtacttatagtgtgctatttcttca	CRISPR spacer
ccaccccactaatagtctgctatttcttca	Protospacer
. * . .*** ***** *************

44. spacer 2.12|2092355|30|NZ_CP048279|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP018696 (Klebsiella pneumoniae strain Kp_Goe_149832 plasmid pKp_Goe_832-1, complete sequence) position: , mismatch: 8, identity: 0.733

taagtgtacttatagtgtgctatttcttca	CRISPR spacer
ccaccccactaatagtctgctatttcttca	Protospacer
. * . .*** ***** *************

45. spacer 2.12|2092355|30|NZ_CP048279|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP018708 (Klebsiella pneumoniae strain Kp_Goe_827026 plasmid pKp_Goe_026-1, complete sequence) position: , mismatch: 8, identity: 0.733

taagtgtacttatagtgtgctatttcttca	CRISPR spacer
ccaccccactaatagtctgctatttcttca	Protospacer
. * . .*** ***** *************

46. spacer 1.2|140156|33|NZ_CP048279|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP007513 (Bacillus bombysepticus plasmid pBb, complete genome) position: , mismatch: 9, identity: 0.727

aattatttttttgaattctttatattttttaga	CRISPR spacer
ttctccttttttaatttctttatattttttatc	Protospacer
  .* .******.* ****************

47. spacer 1.2|140156|33|NZ_CP048279|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP050184 (Bacillus thuringiensis strain HER1410 plasmid pLUSID1, complete sequence) position: , mismatch: 9, identity: 0.727

aattatttttttgaattctttatattttttaga	CRISPR spacer
ttctccttttttaatttctttatattttttatc	Protospacer
  .* .******.* ****************

48. spacer 1.2|140156|33|NZ_CP048279|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP033050 (Virgibacillus halodenitrificans strain Bac324 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

aattat-ttttttgaattctttatattttttaga	CRISPR spacer
-ctgacattttttgaatcctttctattttttctc	Protospacer
  * *. **********.**** ********

49. spacer 2.3|2091963|30|NZ_CP048279|PILER-CR matches to NC_048697 (Pseudomonas phage Littlefix, complete genome) position: , mismatch: 9, identity: 0.7

cggttgaagatattaaagatgagctagcca	CRISPR spacer
tggttgaagatattcaagatgaaatcatgg	Protospacer
.************* *******. * .. .

50. spacer 2.6|2091960|31|NZ_CP048279|CRT,CRISPRCasFinder matches to AP011616 (Thermus phage phiYS40 DNA, complete genome) position: , mismatch: 9, identity: 0.71

acggttgaagatattaaagatgagctagcca	CRISPR spacer
ttaattgaagaaattaaagatgagctttctt	Protospacer
 ...******* **************  *.

51. spacer 2.6|2091960|31|NZ_CP048279|CRT,CRISPRCasFinder matches to DQ997624 (Thermus thermophilus phage YS40, complete genome) position: , mismatch: 9, identity: 0.71

acggttgaagatattaaagatgagctagcca	CRISPR spacer
ttaattgaagaaattaaagatgagctttctt	Protospacer
 ...******* **************  *.

52. spacer 2.6|2091960|31|NZ_CP048279|CRT,CRISPRCasFinder matches to NC_008584 (Thermus phage phiYS40, complete genome) position: , mismatch: 9, identity: 0.71

acggttgaagatattaaagatgagctagcca	CRISPR spacer
ttaattgaagaaattaaagatgagctttctt	Protospacer
 ...******* **************  *.

53. spacer 2.6|2091960|31|NZ_CP048279|CRT,CRISPRCasFinder matches to NZ_CP049807 (Acinetobacter pittii strain A1254 plasmid pA1254_1, complete sequence) position: , mismatch: 9, identity: 0.71

acggttgaagatattaaagatgagctagcca	CRISPR spacer
cagattgaagagattaaagaagagctattac	Protospacer
  *.******* ******** ****** .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

12985 : 81108

Streptococcus_phage(25.0%)

transposase,tRNA,protease

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_162680760.1\|12985_14266_+\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	1.1e-89	51.2
WP_162680761.1\|14578_15271_+	AzlC family ABC transporter permease	NA	NA	NA	NA
WP_162680762.1\|15267_15597_+	AzlD domain-containing protein	NA	NA	NA	NA
WP_162680763.1\|15852_16818_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_162680764.1\|17050_17962_+	DUF2232 domain-containing protein	NA	NA	NA	NA
WP_162680765.1\|17966_19934_+	DHH family phosphoesterase	NA	NA	NA	NA
WP_162680766.1\|19930_20377_+	50S ribosomal protein L9	NA	NA	NA	NA
WP_162680767.1\|20834_22235_+	replicative DNA helicase	A0A1P8VVQ6	Streptococcus_phage	3.6e-115	50.2
WP_162680768.1\|22607_23891_+	adenylosuccinate synthase	A0A2P1EKE7	Megavirus	2.0e-67	34.9
WP_162680769.1\|24110_25004_-	YitT family protein	NA	NA	NA	NA
WP_162680770.1\|27215_28424_-\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	2.2e-68	40.3
WP_014612681.1\|29597_30299_+	response regulator transcription factor	W8CYM9	Bacillus_phage	6.0e-42	38.8
WP_162680771.1\|30311_32144_+	cell wall metabolism sensor histidine kinase WalK	W8CYF6	Bacillus_phage	2.5e-31	31.3
WP_162680772.1\|32133_33471_+	hypothetical protein	NA	NA	NA	NA
WP_162680773.1\|33467_34247_+	hypothetical protein	NA	NA	NA	NA
WP_162680774.1\|34269_35052_+	MBL fold metallo-hydrolase	A0A0C5AJ83	Bacteriophage	5.3e-39	37.2
WP_162680775.1\|35464_35944_+	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	NA	NA	NA	NA
WP_162682956.1\|36128_37037_-\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	2.7e-55	41.1
WP_162682957.1\|37036_37228_-\|transposase	transposase	NA	NA	NA	NA
WP_162680776.1\|37394_37517_-	type I toxin-antitoxin system Fst family toxin	NA	NA	NA	NA
WP_162680777.1\|39576_40803_-	MFS transporter	NA	NA	NA	NA
WP_162680778.1\|41120_41708_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_162680779.1\|41700_42525_+	hypothetical protein	NA	NA	NA	NA
WP_162680780.1\|42514_42775_+	PqqD family protein	NA	NA	NA	NA
WP_162680781.1\|42794_43739_+	HAD family phosphatase	NA	NA	NA	NA
WP_162680782.1\|43740_44829_+	myo-inositol-1-phosphate synthase	A0A067XQY1	Caulobacter_phage	4.2e-42	34.1
WP_162680783.1\|44821_46021_+	methionine adenosyltransferase	NA	NA	NA	NA
WP_162680784.1\|46032_47256_+	DegT/DnrJ/EryC1/StrS aminotransferase	A0A2K9L0G1	Tupanvirus	7.0e-30	31.2
WP_162680785.1\|47266_48031_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_162680786.1\|48043_49042_+	hypothetical protein	NA	NA	NA	NA
WP_162682958.1\|49031_49508_+	kinase	NA	NA	NA	NA
WP_162680787.1\|49510_50485_+	hypothetical protein	NA	NA	NA	NA
WP_162680788.1\|50465_51206_+	hypothetical protein	NA	NA	NA	NA
WP_162680789.1\|51209_52121_+	phosphotransferase	NA	NA	NA	NA
WP_162680790.1\|52117_52561_+	NUDIX hydrolase	NA	NA	NA	NA
WP_162680791.1\|53306_54050_-	ATP-binding protein	A0A2L1IVB6	Escherichia_phage	2.3e-12	26.6
WP_162680792.1\|54039_55575_-\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_162680793.1\|56321_56735_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_162680794.1\|56727_57276_+	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_162680795.1\|58435_59611_+	DUF418 domain-containing protein	NA	NA	NA	NA
WP_162680796.1\|59715_59946_+	hypothetical protein	NA	NA	NA	NA
WP_162680797.1\|60080_60302_+	hypothetical protein	NA	NA	NA	NA
WP_162680798.1\|60742_61858_+	alanine dehydrogenase	NA	NA	NA	NA
WP_162680799.1\|61894_62935_+	bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB	NA	NA	NA	NA
WP_162680800.1\|62970_64284_+	amino acid permease	NA	NA	NA	NA
WP_162680801.1\|65551_67609_+	copper-translocating P-type ATPase	A0A218MNH6	uncultured_virus	1.9e-67	30.3
WP_162680802.1\|68186_70298_+	AAA family ATPase	NA	NA	NA	NA
WP_162680803.1\|70382_70991_+	stage II sporulation protein M	NA	NA	NA	NA
WP_162680804.1\|71214_72213_+	sphingomyelin phosphodiesterase	A0A1P8L6H7	Staphylococcus_phage	2.2e-106	66.2
WP_162680805.1\|72547_74650_+	sialidase	NA	NA	NA	NA
WP_162680806.1\|74670_74811_+	hypothetical protein	NA	NA	NA	NA
WP_162680807.1\|76439_77345_+	restriction endonuclease	NA	NA	NA	NA
WP_162680808.1\|77627_77834_-	hypothetical protein	NA	NA	NA	NA
WP_162680809.1\|78340_79150_+	Dam family site-specific DNA-(adenine-N6)-methyltransferase	A0A1S5PRR3	Streptococcus_phage	1.6e-54	44.6
WP_162682959.1\|79213_79942_+	site-specific DNA-methyltransferase	A0A249XUJ2	Enterococcus_phage	5.4e-30	34.8
WP_162680810.1\|80703_81108_+\|transposase	IS200/IS605 family transposase	A0A286QN76	Streptococcus_phage	1.1e-53	76.2

DBSCAN-SWA_2

284026 : 319889

Enterococcus_phage(27.27%)

holin,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_162680811.1\|284026_285169_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A288TXV8	Enterococcus_phage	5.3e-197	89.2
WP_019166837.1\|285358_285985_-	FMN-dependent NADH-azoreductase	NA	NA	NA	NA
WP_162680953.1\|287010_287649_+	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_162680954.1\|287894_289106_-	multidrug effflux MFS transporter	NA	NA	NA	NA
WP_162680955.1\|289206_289776_-	isochorismatase family protein	NA	NA	NA	NA
WP_162682968.1\|289807_290332_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_162682969.1\|290610_291054_+	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_162680956.1\|291313_292729_-	aminotransferase class V-fold PLP-dependent enzyme	NA	NA	NA	NA
WP_162680957.1\|292997_293300_-	SPIN family peroxidase inhibitor	NA	NA	NA	NA
WP_162682970.1\|294174_294609_-	Hsp20/alpha crystallin family protein	NA	NA	NA	NA
WP_162680958.1\|294935_295466_+	putative metal-dependent hydrolase	D0R7I3	Paenibacillus_phage	3.2e-11	31.8
WP_162680959.1\|295713_297204_+	catalase	A0A2K9L0T1	Tupanvirus	5.1e-91	42.8
WP_162680960.1\|297424_297748_+	hypothetical protein	NA	NA	NA	NA
WP_019166850.1\|297869_298316_+	DNA starvation/stationary phase protection protein	A0A0A7RTZ1	Clostridium_phage	7.7e-35	50.0
WP_162680961.1\|298664_298772_+\|holin	putative holin-like toxin	NA	NA	NA	NA
WP_162680962.1\|299559_300936_+	sodium:solute symporter	NA	NA	NA	NA
WP_162680963.1\|301011_302169_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_162680964.1\|302333_303476_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A288TXV8	Enterococcus_phage	2.6e-196	88.9
WP_162680965.1\|303491_303896_-\|transposase	IS200/IS605 family transposase	A0A286QN76	Streptococcus_phage	3.7e-52	74.6
WP_162682971.1\|304630_304894_-	type II toxin-antitoxin system RelE/ParE family toxin	A0A1S5S8E8	Streptococcus_phage	2.8e-21	55.8
WP_162680966.1\|304890_305112_-	CopG family transcriptional regulator	NA	NA	NA	NA
WP_162680967.1\|306428_307538_+	NAD(P)-binding domain-containing protein	NA	NA	NA	NA
WP_162680968.1\|307531_308866_+	ferrous iron transporter B	NA	NA	NA	NA
WP_162680969.1\|309021_310071_+	ABC transporter permease	NA	NA	NA	NA
WP_162680970.1\|310083_310752_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.0e-30	35.3
WP_162682972.1\|310835_311258_+	Rrf2 family transcriptional regulator	NA	NA	NA	NA
WP_162680971.1\|311258_312584_+	FAD-containing oxidoreductase	A0A2K5B2C5	Erysipelothrix_phage	1.7e-101	45.0
WP_162680972.1\|312972_313077_-	type I toxin-antitoxin system Fst family toxin	NA	NA	NA	NA
WP_162682973.1\|313445_314405_-	amidohydrolase	NA	NA	NA	NA
WP_162680973.1\|314690_316088_-	multidrug efflux MFS transporter	NA	NA	NA	NA
WP_162680974.1\|316213_317005_+	arylamine N-acetyltransferase	NA	NA	NA	NA
WP_162680975.1\|317020_317596_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_162680976.1\|317722_318118_-	ATP-binding protein	NA	NA	NA	NA
WP_162680811.1\|318326_319469_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A288TXV8	Enterococcus_phage	5.3e-197	89.2
WP_162680977.1\|319484_319889_-\|transposase	IS200/IS605 family transposase	A0A286QN76	Streptococcus_phage	5.6e-53	75.4

DBSCAN-SWA_3

421139 : 554347

107

Streptococcus_phage(20.83%)

holin,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_162680977.1\|421139_421544_+\|transposase	IS200/IS605 family transposase	A0A286QN76	Streptococcus_phage	5.6e-53	75.4
WP_162681057.1\|421559_422702_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A288TXV8	Enterococcus_phage	2.4e-197	89.4
WP_162681058.1\|423229_424600_+	melibiose:sodium transporter MelB	NA	NA	NA	NA
WP_162681059.1\|424626_427623_+	beta-galactosidase	L0N6M2	Herpes_simplex_virus	7.3e-121	30.0
WP_162681060.1\|427678_428626_-	nucleoside hydrolase	NA	NA	NA	NA
WP_162681061.1\|429846_431337_+	cardiolipin synthase	NA	NA	NA	NA
WP_162681062.1\|431810_433547_+	phosphomethylpyrimidine synthase ThiC	NA	NA	NA	NA
WP_162681063.1\|433753_434764_+	HoxN/HupN/NixA family nickel/cobalt transporter	NA	NA	NA	NA
WP_162681064.1\|434931_436110_-	MFS transporter	NA	NA	NA	NA
WP_162681065.1\|436218_436767_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_162681066.1\|437638_438274_-	hypothetical protein	NA	NA	NA	NA
WP_162681067.1\|438460_439189_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_162682978.1\|439323_440745_+	alkaline phosphatase	NA	NA	NA	NA
WP_162681068.1\|440898_441291_+	(deoxy)nucleoside triphosphate pyrophosphohydrolase	NA	NA	NA	NA
WP_162681069.1\|441295_444160_+	DEAD/DEAH box helicase	G8EY40	Synechococcus_phage	5.7e-22	25.3
WP_162681070.1\|444320_445643_+	divalent metal cation transporter	NA	NA	NA	NA
WP_162681071.1\|446031_447657_+	BCCT family transporter	A0A2I7QNT1	Vibrio_phage	6.5e-15	20.9
WP_162681072.1\|448688_449240_-	GbsR/MarR family transcriptional regulator	NA	NA	NA	NA
WP_162681073.1\|449461_450955_+	betaine-aldehyde dehydrogenase	NA	NA	NA	NA
WP_162681074.1\|451084_452779_+\|holin	choline dehydrogenase	A0A1V0S9J5	Catovirus	1.9e-54	30.3
WP_162681075.1\|453062_454037_+	ornithine carbamoyltransferase	NA	NA	NA	NA
WP_162681076.1\|454468_455098_-	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE	NA	NA	NA	NA
WP_162681077.1\|455088_455853_-	imidazole glycerol phosphate synthase subunit HisF	NA	NA	NA	NA
WP_162681078.1\|455849_456554_-	1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide isomerase	NA	NA	NA	NA
WP_162681079.1\|456546_457122_-	imidazole glycerol phosphate synthase subunit HisH	NA	NA	NA	NA
WP_162681080.1\|457118_457700_-	imidazoleglycerol-phosphate dehydratase HisB	NA	NA	NA	NA
WP_162681081.1\|457683_458697_-	histidinol-phosphate aminotransferase family protein	A0A1X6WGT4	Pacmanvirus	6.9e-07	20.3
WP_162681082.1\|458693_459953_-	histidinol dehydrogenase	NA	NA	NA	NA
WP_162681083.1\|459942_460557_-	ATP phosphoribosyltransferase	NA	NA	NA	NA
WP_162681084.1\|460572_461382_-	ATP phosphoribosyltransferase regulatory subunit	NA	NA	NA	NA
WP_162681085.1\|461715_462378_+	deoxyribose-phosphate aldolase	NA	NA	NA	NA
WP_162681086.1\|462411_463590_+	phosphopentomutase	NA	NA	NA	NA
WP_162681087.1\|464754_465717_+	dihydroxyacetone kinase subunit DhaK	NA	NA	NA	NA
WP_162681088.1\|465739_466321_+	dihydroxyacetone kinase subunit L	NA	NA	NA	NA
WP_096547169.1\|466317_466677_+	PTS-dependent dihydroxyacetone kinase phosphotransferase subunit DhaM	NA	NA	NA	NA
WP_162682979.1\|466743_467094_-	alkylphosphonate utilization protein	NA	NA	NA	NA
WP_162681089.1\|467246_468635_+	NAD-dependent succinate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_162681090.1\|470337_470499_+	signal protein	NA	NA	NA	NA
WP_162681091.1\|470554_471661_+	serine hydrolase	NA	NA	NA	NA
WP_162681092.1\|471705_472674_+	phosphotransferase	NA	NA	NA	NA
WP_162681093.1\|472694_473573_+	hypothetical protein	NA	NA	NA	NA
WP_162681094.1\|473592_473790_+	hypothetical protein	NA	NA	NA	NA
WP_162681095.1\|473786_474674_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	9.6e-21	28.6
WP_162681096.1\|474686_475436_+	hypothetical protein	NA	NA	NA	NA
WP_162681097.1\|475447_476389_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	2.9e-23	30.7
WP_162681098.1\|476375_477188_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_162681099.1\|477202_478321_+	zinc-binding alcohol dehydrogenase family protein	NA	NA	NA	NA
WP_162681100.1\|480855_482064_-\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	5.8e-69	40.4
WP_162680791.1\|482348_483092_-	ATP-binding protein	A0A2L1IVB6	Escherichia_phage	2.3e-12	26.6
WP_162680792.1\|483081_484617_-\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_162681101.1\|485710_486016_+	hypothetical protein	NA	NA	NA	NA
WP_162681102.1\|486182_486512_+	staphylobilin-forming heme oxygenase IsdG	NA	NA	NA	NA
WP_162680810.1\|487162_487567_+\|transposase	IS200/IS605 family transposase	A0A286QN76	Streptococcus_phage	1.1e-53	76.2
WP_162680811.1\|487582_488725_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A288TXV8	Enterococcus_phage	5.3e-197	89.2
WP_162681103.1\|489026_489992_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_162681104.1\|490021_490747_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_162681105.1\|490934_492857_+	PTS transporter subunit EIIA	NA	NA	NA	NA
WP_162681106.1\|492998_494858_+	cell wall anchor protein	NA	NA	NA	NA
WP_162681107.1\|495453_497508_-	amidase domain-containing protein	S5M9Y4	Brevibacillus_phage	6.3e-07	32.9
WP_162681108.1\|497829_500664_+	YhgE/Pip domain-containing protein	NA	NA	NA	NA
WP_162681109.1\|501939_502569_+	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_162681110.1\|502776_503505_+	epoxyqueuosine reductase QueH	NA	NA	NA	NA
WP_162681111.1\|503608_505105_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_162681112.1\|505094_506081_+	ABC transporter permease	NA	NA	NA	NA
WP_162681113.1\|506077_506902_+	ABC transporter permease	NA	NA	NA	NA
WP_162681114.1\|506894_507662_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.7e-11	26.0
WP_162681115.1\|507663_508353_+	ATP-binding cassette domain-containing protein	A0A2K9L0W2	Tupanvirus	2.0e-05	21.6
WP_162681116.1\|508494_510669_-	bifunctional glycosyltransferase family 2 protein/CDP-glycerol:glycerophosphate glycerophosphotransferase	NA	NA	NA	NA
WP_162681117.1\|510863_511799_+	SDR family NAD(P)-dependent oxidoreductase	A0A1V0SAI6	Catovirus	7.0e-46	36.0
WP_162681118.1\|512054_514574_+	glycosyltransferase	NA	NA	NA	NA
WP_162681119.1\|514631_516131_-	tripartite tricarboxylate transporter permease	NA	NA	NA	NA
WP_162681120.1\|516143_516587_-	tripartite tricarboxylate transporter TctB family protein	NA	NA	NA	NA
WP_162681121.1\|516605_517595_-	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_162681122.1\|517852_518692_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_162681123.1\|518636_520895_-	alpha-galactosidase	NA	NA	NA	NA
WP_162682980.1\|520875_522282_-	melibiose:sodium transporter MelB	NA	NA	NA	NA
WP_162681124.1\|522904_523567_-	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_162681125.1\|523679_524543_+	phosphotransferase	NA	NA	NA	NA
WP_162681126.1\|524529_524976_+	DUF1648 domain-containing protein	NA	NA	NA	NA
WP_162681127.1\|525044_525647_-	hypothetical protein	NA	NA	NA	NA
WP_162681128.1\|526553_527606_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_162681129.1\|527602_528298_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.4e-35	38.7
WP_162681130.1\|528281_529457_+	FtsX-like permease family protein	NA	NA	NA	NA
WP_162681131.1\|529713_530118_+\|transposase	IS200/IS605 family transposase	A0A286QN76	Streptococcus_phage	3.3e-53	75.4
WP_162680811.1\|530133_531276_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A288TXV8	Enterococcus_phage	5.3e-197	89.2
WP_162681132.1\|531583_532528_+	cation transporter	NA	NA	NA	NA
WP_162681133.1\|532708_533626_-	urea transporter	NA	NA	NA	NA
WP_014612952.1\|533878_534181_+	urease subunit gamma	NA	NA	NA	NA
WP_162682981.1\|534192_534549_+	urease subunit beta	NA	NA	NA	NA
WP_162681134.1\|534545_536261_+	urease subunit alpha	NA	NA	NA	NA
WP_162681135.1\|536627_537173_+	dCTP deaminase	R4T7I4	Halovirus	5.3e-30	43.6
WP_162681136.1\|537173_538076_+	GTP-binding protein	NA	NA	NA	NA
WP_162681137.1\|538356_538779_+	universal stress protein	NA	NA	NA	NA
WP_162681138.1\|539011_539272_+	ferredoxin	NA	NA	NA	NA
WP_162681139.1\|539271_540957_+	hypothetical protein	NA	NA	NA	NA
WP_162681140.1\|540975_542223_+	ATP-grasp domain-containing protein	NA	NA	NA	NA
WP_162681141.1\|542219_543419_+	ATP-grasp domain-containing protein	NA	NA	NA	NA
WP_162681142.1\|543486_543684_+	hypothetical protein	NA	NA	NA	NA
WP_162681143.1\|543916_545146_-	MFS transporter	NA	NA	NA	NA
WP_162681144.1\|545302_546232_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_162681145.1\|546698_547382_+	LrgB family protein	NA	NA	NA	NA
WP_162680811.1\|547539_548682_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A288TXV8	Enterococcus_phage	5.3e-197	89.2
WP_162680965.1\|548697_549102_-\|transposase	IS200/IS605 family transposase	A0A286QN76	Streptococcus_phage	3.7e-52	74.6
WP_162681146.1\|549494_550481_-	ImpB/MucB/SamB family protein	O64031	Bacillus_phage	8.6e-71	49.0
WP_162681147.1\|550571_551369_-	hypothetical protein	NA	NA	NA	NA
WP_162681148.1\|551346_552636_-	4Fe-4S cluster-binding domain-containing protein	NA	NA	NA	NA
WP_162680792.1\|552811_554347_+\|transposase	IS21 family transposase	NA	NA	NA	NA

DBSCAN-SWA_4

751512 : 810910

Streptococcus_phage(33.33%)

holin,transposase,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_162680770.1\|751512_752721_+\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	2.2e-68	40.3
WP_162681298.1\|752993_754718_+\|transposase	IS1182 family transposase	A0ZS58	Staphylococcus_virus	1.7e-151	51.2
WP_162681299.1\|754731_755661_-	formimidoylglutamase	NA	NA	NA	NA
WP_162681300.1\|756090_756975_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_162681301.1\|757461_760926_+	helicase-exonuclease AddAB subunit AddB	NA	NA	NA	NA
WP_162681302.1\|760922_764567_+	helicase-exonuclease AddAB subunit AddA	A7KV33	Bacillus_phage	3.0e-20	24.8
WP_162681303.1\|764649_765555_+	fumarylacetoacetate hydrolase family protein	NA	NA	NA	NA
WP_162681304.1\|766226_766616_+	YisL family protein	NA	NA	NA	NA
WP_162681305.1\|766726_768052_-	CoA-disulfide reductase	NA	NA	NA	NA
WP_162681306.1\|768081_768906_-	HAD family phosphatase	NA	NA	NA	NA
WP_014614389.1\|769019_769328_+	metal-sulfur cluster assembly factor	NA	NA	NA	NA
WP_162682986.1\|769596_771441_+	acetyltransferase	A0A166XZF2	Gordonia_phage	1.1e-34	33.3
WP_162681307.1\|771651_774276_+	ATP-dependent chaperone ClpB	A0A1C3S747	Escherichia_phage	2.4e-120	35.5
WP_162681308.1\|774947_775853_+	5'-nucleotidase, lipoprotein e(P4) family	NA	NA	NA	NA
WP_162681309.1\|776015_776213_-	YjzD family protein	NA	NA	NA	NA
WP_096596531.1\|776362_777304_+	ketoacyl-ACP synthase III	NA	NA	NA	NA
WP_162681310.1\|777322_778567_+	beta-ketoacyl-ACP synthase II	NA	NA	NA	NA
WP_162681311.1\|780293_780671_-	DUF3899 domain-containing protein	NA	NA	NA	NA
WP_162681312.1\|780916_781843_+	ABC transporter permease	NA	NA	NA	NA
WP_162681313.1\|781842_782904_+	ABC transporter permease	NA	NA	NA	NA
WP_162681314.1\|782918_783998_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.2e-18	31.1
WP_162681315.1\|783990_784932_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	2.9e-23	34.2
WP_162681316.1\|784954_786619_+	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_162681317.1\|787367_788357_-\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_162681318.1\|788668_789064_+	transcriptional regulator Spx	NA	NA	NA	NA
WP_162681319.1\|789399_790098_+	adaptor protein MecA	NA	NA	NA	NA
WP_162682987.1\|790696_792013_+\|protease	trypsin-like serine protease	NA	NA	NA	NA
WP_162681320.1\|792031_792694_+	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_162681321.1\|792960_793926_+	competence protein CoiA	NA	NA	NA	NA
WP_019165984.1\|793999_795808_+	oligoendopeptidase F	A0A1X9I5X5	Streptococcus_phage	2.4e-42	24.1
WP_162681322.1\|796563_797352_-	DsbA family protein	NA	NA	NA	NA
WP_162681323.1\|797368_797740_-	globin	NA	NA	NA	NA
WP_162681324.1\|798088_798670_-	CYTH domain-containing protein	NA	NA	NA	NA
WP_162681325.1\|798800_799148_+	hypothetical protein	NA	NA	NA	NA
WP_014614363.1\|799164_799803_+	GTP pyrophosphokinase family protein	NA	NA	NA	NA
WP_096596542.1\|799814_800624_+	NAD kinase	NA	NA	NA	NA
WP_162681326.1\|800620_801475_+	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_162681327.1\|801488_802889_+	magnesium transporter	NA	NA	NA	NA
WP_162681328.1\|802899_804738_+	sodium:proton antiporter	NA	NA	NA	NA
WP_162681329.1\|804884_805655_+	enoyl-ACP reductase FabI	NA	NA	NA	NA
WP_162681330.1\|806184_806292_+\|holin	putative holin-like toxin	NA	NA	NA	NA
WP_162681331.1\|806613_807711_-	AI-2E family transporter	NA	NA	NA	NA
WP_162681332.1\|807928_809500_+	alanine:cation symporter family protein	NA	NA	NA	NA
WP_162681333.1\|809602_810343_+	esterase family protein	NA	NA	NA	NA
WP_162680810.1\|810505_810910_+\|transposase	IS200/IS605 family transposase	A0A286QN76	Streptococcus_phage	1.1e-53	76.2

DBSCAN-SWA_5

896347 : 904767

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_162681391.1\|896347_896830_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	4.0e-21	43.3
WP_162681392.1\|896816_897950_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_162681393.1\|897946_898648_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	G8EYA2	Synechococcus_phage	9.2e-51	44.6
WP_014614277.1\|898650_898911_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_162681394.1\|898912_899584_+	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
WP_162681395.1\|899576_901766_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	5.6e-139	40.1
WP_162681396.1\|901744_903166_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	7.1e-50	33.6
WP_162681397.1\|903169_904201_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	3.4e-62	42.1
WP_162681398.1\|904200_904767_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	4.0e-28	38.9

DBSCAN-SWA_6

985293 : 995148

Staphylococcus_phage(53.33%)

portal,head,terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_162682994.1\|985293_985857_-	hypothetical protein	A0A1X9I5H8	Streptococcus_phage	5.0e-15	31.6
WP_162680744.1\|985862_986114_-	hypothetical protein	A0A1J0MFV1	Staphylococcus_phage	2.4e-22	63.9
WP_162681462.1\|986267_986504_-	hypothetical protein	NA	NA	NA	NA
WP_162681463.1\|987086_987398_-	hypothetical protein	A0A2H4J741	uncultured_Caudovirales_phage	1.4e-22	53.5
WP_162681464.1\|987496_987673_+	transcriptional regulator	A0A2H4J9B5	uncultured_Caudovirales_phage	3.9e-11	62.1
WP_162681465.1\|987672_988092_+	transcriptional regulator	I1W651	Staphylococcus_phage	1.1e-46	69.8
WP_162681466.1\|988418_988604_+	type II toxin-antitoxin system HicA family toxin	A0A0D4DC32	Acinetobacter_phage	2.7e-18	75.4
WP_162681467.1\|988638_989034_+	HicB family protein	A0A0K2CYJ8	Paenibacillus_phage	1.1e-24	47.0
WP_162681468.1\|989112_989592_+\|terminase	terminase small subunit	A7J290	Streptococcus_phage	2.5e-15	39.3
WP_162681469.1\|989584_990028_+	hypothetical protein	A0A0H3U2R6	Staphylococcus_phage	5.5e-17	48.0
WP_162682995.1\|990114_991434_+\|portal	phage portal protein	A0A2P1JTZ3	Anoxybacillus_phage	1.3e-98	47.0
WP_162681470.1\|991417_992770_+\|head	phage head morphogenesis protein	A0A1J0MF61	Staphylococcus_phage	7.0e-156	60.9
WP_162681471.1\|992769_992964_+	LSM domain protein	A0A1J0MG79	Staphylococcus_phage	1.4e-17	70.3
WP_162681472.1\|993141_993720_+	DUF4355 domain-containing protein	NA	NA	NA	NA
WP_162682996.1\|994535_994739_+	hypothetical protein	A0A1J0MFV7	Staphylococcus_phage	2.0e-22	78.8
WP_162680745.1\|994739_994928_+	XRE family transcriptional regulator	A0A1W6JNK0	Staphylococcus_phage	8.2e-07	53.2
WP_162681473.1\|995031_995148_+	hypothetical protein	W5R8J7	Staphylococcus_phage	1.6e-05	75.0

DBSCAN-SWA_7

1201767 : 1274665

Staphylococcus_phage(72.06%)

portal,transposase,integrase,tail,head,terminase,capsid,holin,protease

attL 1204192:1204209|attR 1245713:1245730

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_162683007.1\|1201767_1203054_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	2.0e-27	32.1
1204192:1204209	attL	NA	NA	NA	NA
WP_162681622.1\|1204267_1205314_-\|integrase	site-specific integrase	W5R968	Staphylococcus_phage	4.3e-153	75.1
WP_162681623.1\|1205449_1206469_-	hypothetical protein	R9QTP0	Staphylococcus_phage	6.6e-50	37.0
WP_162681624.1\|1206483_1207176_-	helix-turn-helix transcriptional regulator	A0A1J0MFC5	Staphylococcus_phage	6.7e-78	67.9
WP_162681625.1\|1207372_1207588_+	XRE family transcriptional regulator	Q4ZA66	Staphylococcus_virus	3.2e-31	98.6
WP_162681626.1\|1207599_1207860_+	hypothetical protein	NA	NA	NA	NA
WP_096636863.1\|1208128_1208338_+	hypothetical protein	A0A1W6JQ31	Staphylococcus_phage	1.9e-20	65.2
WP_162681627.1\|1208608_1208815_+	hypothetical protein	NA	NA	NA	NA
WP_162681628.1\|1208811_1209057_+	hypothetical protein	NA	NA	NA	NA
WP_162681629.1\|1209049_1209535_+	siphovirus Gp157 family protein	H9A0R4	Staphylococcus_phage	8.1e-06	40.8
WP_162681630.1\|1209535_1209709_+	hypothetical protein	NA	NA	NA	NA
WP_162681631.1\|1209698_1210400_+	AAA family ATPase	A0A1W6JQH5	Staphylococcus_phage	8.0e-87	67.4
WP_162681632.1\|1210523_1211747_+	DEAD/DEAH box helicase	Q9T1H9	Lactobacillus_phage	1.6e-106	48.2
WP_162681633.1\|1211764_1212268_+	DUF669 domain-containing protein	A0A059T5G4	Listeria_phage	8.6e-35	46.1
WP_162681634.1\|1212296_1214603_+	DNA primase	A0A059T6A4	Listeria_phage	2.6e-211	50.1
WP_162681635.1\|1214892_1215201_+	VRR-NUC domain-containing protein	A0A1P8VVL5	Streptococcus_phage	7.1e-32	68.3
WP_162681636.1\|1215558_1216044_+	DUF3310 domain-containing protein	A0A223LGV5	Staphylococcus_phage	3.0e-61	72.7
WP_162681637.1\|1216040_1216292_+	hypothetical protein	A0A223LIA9	Staphylococcus_phage	2.0e-40	98.8
WP_162681638.1\|1216295_1216481_+	hypothetical protein	A0A223LFJ6	Staphylococcus_phage	6.8e-22	86.9
WP_162681639.1\|1216477_1216735_+	hypothetical protein	A0A223LHL9	Staphylococcus_phage	5.4e-25	74.1
WP_162681640.1\|1216734_1217130_+	hypothetical protein	A0A1J0MFL6	Staphylococcus_phage	1.0e-38	61.8
WP_162681641.1\|1217132_1217516_+	hypothetical protein	NA	NA	NA	NA
WP_162681642.1\|1217517_1217889_+	hypothetical protein	A0A142F184	Bacillus_phage	7.0e-34	61.6
WP_162681643.1\|1217908_1218439_+	dUTPase	I1W653	Staphylococcus_phage	2.4e-75	77.3
WP_162681644.1\|1218502_1218730_+	DUF1381 domain-containing protein	A0A1J0MFI3	Staphylococcus_phage	9.6e-18	67.2
WP_162681645.1\|1218869_1219046_+	DUF1514 domain-containing protein	Q4ZD28	Staphylococcus_phage	1.1e-13	72.4
WP_162681646.1\|1219057_1219480_+	transcriptional regulator	A0A1J0MFW0	Staphylococcus_phage	2.2e-68	91.4
WP_162681647.1\|1219606_1219984_+	hypothetical protein	A0A1J0MFN7	Staphylococcus_phage	5.1e-56	89.6
WP_162681648.1\|1219989_1220346_+	HNH endonuclease	A0A1J0MFT4	Staphylococcus_phage	9.0e-63	94.9
WP_162681649.1\|1220440_1220911_+\|terminase	phage terminase small subunit P27 family	A0A1J0MG04	Staphylococcus_phage	3.1e-71	88.5
WP_162681650.1\|1220910_1222614_+\|terminase	terminase	A0A1J0MGD9	Staphylococcus_phage	0.0e+00	94.3
WP_162681651.1\|1222625_1222823_+	hypothetical protein	A0A1J0MFN2	Staphylococcus_phage	2.1e-21	90.8
WP_162683008.1\|1222885_1224100_+\|portal	phage portal protein	A0A1J0MFU3	Staphylococcus_phage	4.7e-220	95.0
WP_162681652.1\|1224074_1224647_+\|head,protease	HK97 family phage prohead protease	A0A1J0MFL1	Staphylococcus_phage	8.4e-103	97.9
WP_162681653.1\|1224725_1225949_+\|capsid	phage major capsid protein	A0A1J0MFW8	Staphylococcus_phage	4.3e-189	85.3
WP_162681654.1\|1226132_1226423_+\|head,tail	phage head-tail adapter protein	A0A1J0MFU4	Staphylococcus_phage	1.1e-45	93.5
WP_162681655.1\|1226403_1226736_+\|head,tail	head-tail adaptor protein	A0A1J0MG09	Staphylococcus_phage	1.2e-56	97.3
WP_162681656.1\|1226735_1227113_+	HK97 gp10 family phage protein	A0A1J0MGE3	Staphylococcus_phage	6.2e-62	97.6
WP_162681657.1\|1227109_1227472_+	hypothetical protein	A0A1J0MFP0	Staphylococcus_phage	1.9e-60	94.2
WP_162681658.1\|1227483_1228425_+	hypothetical protein	A0A1J0MFV0	Staphylococcus_phage	6.2e-151	86.9
WP_162681659.1\|1228491_1228938_+	hypothetical protein	A0A1J0MFL9	Staphylococcus_phage	2.3e-39	56.1
WP_162681660.1\|1229138_1230173_+\|tail	phage tail tape measure protein	A0A1J0MFP9	Staphylococcus_phage	3.0e-114	96.4
WP_162681661.1\|1230395_1234265_+\|tail	phage tail tape measure protein	A0A1J0MFP9	Staphylococcus_phage	0.0e+00	70.0
WP_162681662.1\|1234264_1235755_+\|tail	phage tail protein	Q4ZD64	Staphylococcus_phage	5.1e-216	72.3
WP_162683009.1\|1238803_1240816_+	hypothetical protein	Q4ZD63	Staphylococcus_phage	2.5e-125	50.9
WP_162680746.1\|1240827_1240977_+	hypothetical protein	Q4ZD62	Staphylococcus_phage	2.5e-14	85.7
WP_162681663.1\|1241023_1241314_+	hypothetical protein	Q4ZD61	Staphylococcus_phage	1.6e-38	87.1
WP_162681664.1\|1241351_1241774_+	hypothetical protein	A0A2H4JIB4	uncultured_Caudovirales_phage	4.7e-34	52.5
WP_162681665.1\|1241757_1242153_+	hypothetical protein	A0A1W6JPV8	Staphylococcus_phage	5.0e-30	48.4
WP_020219676.1\|1242197_1242446_+	hypothetical protein	Q4ZD59	Staphylococcus_phage	4.8e-39	98.8
WP_162681666.1\|1242447_1243908_+	peptidoglycan DD-metalloendopeptidase family protein	Q4ZD58	Staphylococcus_phage	9.9e-273	92.0
WP_162681667.1\|1244023_1244689_-	NYN domain-containing protein	A0A0R6PGY5	Moraxella_phage	7.4e-26	34.6
WP_162681668.1\|1245370_1245568_+	hypothetical protein	Q4ZBW5	Staphylococcus_virus	1.2e-11	50.8
WP_162681669.1\|1246443_1246842_+	hypothetical protein	NA	NA	NA	NA
1245713:1245730	attR	NA	NA	NA	NA
WP_162681670.1\|1247144_1247360_+	hypothetical protein	NA	NA	NA	NA
WP_162681671.1\|1248006_1248198_+	hypothetical protein	M9NUJ7	Staphylococcus_phage	3.7e-15	66.2
WP_162680747.1\|1248777_1249251_+	hypothetical protein	NA	NA	NA	NA
WP_162681672.1\|1249230_1249851_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	8.4e-32	34.0
WP_162683010.1\|1252072_1253359_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	4.5e-27	32.1
WP_162681673.1\|1253619_1254828_+\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	4.2e-67	40.0
WP_162681674.1\|1255100_1256792_+\|transposase	IS1182 family transposase	A0ZS58	Staphylococcus_virus	1.7e-151	51.2
WP_162681675.1\|1256780_1257557_-	DUF1828 domain-containing protein	NA	NA	NA	NA
WP_096662130.1\|1257578_1257815_-	hypothetical protein	NA	NA	NA	NA
WP_162681676.1\|1258074_1258359_-	hypothetical protein	NA	NA	NA	NA
WP_162681677.1\|1258357_1259134_+	hypothetical protein	A0A059T7K2	Staphylococcus_phage	4.7e-48	53.0
WP_162683011.1\|1259220_1260555_+\|portal	phage portal protein	A0A2P1JTZ3	Anoxybacillus_phage	1.2e-99	46.7
WP_162681678.1\|1260538_1261891_+\|head	phage head morphogenesis protein	A0A1J0MF61	Staphylococcus_phage	1.0e-159	61.2
WP_162681679.1\|1261887_1262082_+	LSM domain protein	A0A1J0MG79	Staphylococcus_phage	9.1e-17	64.1
WP_162681680.1\|1262266_1262857_+	DUF4355 domain-containing protein	NA	NA	NA	NA
WP_162681681.1\|1263820_1264144_+\|head,tail	phage head-tail connector protein	Q4ZE31	Staphylococcus_virus	6.1e-18	47.9
WP_162681682.1\|1264167_1264464_+	hypothetical protein	NA	NA	NA	NA
WP_162683012.1\|1264444_1264792_+	hypothetical protein	H9A0N6	Staphylococcus_phage	4.3e-25	51.7
WP_162681683.1\|1264797_1265187_+	hypothetical protein	NA	NA	NA	NA
WP_162681684.1\|1265204_1265753_+\|tail	phage major tail protein, TP901-1 family	A0EWT6	Staphylococcus_virus	7.0e-30	44.5
WP_162681685.1\|1265806_1266160_+\|tail	phage tail protein	A0A1J0MFH0	Staphylococcus_phage	6.9e-23	46.2
WP_162681686.1\|1266228_1266576_+	hypothetical protein	Q4ZE25	Staphylococcus_virus	6.4e-21	48.7
WP_162681687.1\|1266588_1269432_+\|tail	phage tail protein	A0A1J0MFN4	Staphylococcus_phage	3.1e-12	36.8
WP_162683014.1\|1269531_1270365_+\|tail	phage tail family protein	A0A1W6JNQ4	Staphylococcus_phage	3.1e-53	40.9
WP_162683013.1\|1270386_1270737_+\|holin	phage holin family protein	A0A1S6KVE0	Staphylococcus_phage	1.5e-33	64.2
WP_162681688.1\|1270755_1271703_+	N-acetylmuramoyl-L-alanine amidase	A0A1P8CMK9	Staphylococcus_phage	7.7e-85	52.0
WP_162683015.1\|1271971_1272469_+	hypothetical protein	NA	NA	NA	NA
WP_162681689.1\|1272487_1272853_+	hypothetical protein	NA	NA	NA	NA
WP_162681690.1\|1273326_1273524_+	hypothetical protein	Q4ZBW5	Staphylococcus_virus	6.8e-12	50.8
WP_162681691.1\|1273745_1273997_+	hypothetical protein	NA	NA	NA	NA
WP_162680748.1\|1274476_1274665_+	XRE family transcriptional regulator	M9NSU5	Staphylococcus_phage	5.2e-09	53.6

DBSCAN-SWA_8

1291686 : 1315405

Staphylococcus_phage(95.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_162681705.1\|1291686_1293090_+	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	1.5e-137	53.0
WP_162681706.1\|1293092_1294079_+	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	8.6e-79	47.9
WP_162681707.1\|1294054_1294306_-	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	6.0e-29	70.6
WP_162681708.1\|1294364_1294835_+	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	2.7e-38	52.9
WP_162683018.1\|1294839_1295592_+	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	2.3e-84	61.2
WP_162681709.1\|1295903_1297586_+	hypothetical protein	NA	NA	NA	NA
WP_162681710.1\|1297710_1299303_-	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	1.2e-242	76.4
WP_162681711.1\|1299767_1300967_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.3e-177	79.3
WP_162681712.1\|1301054_1301966_+	hypothetical protein	A0A2H4PQQ8	Staphylococcus_phage	1.2e-87	67.9
WP_162681713.1\|1302136_1302973_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	5.9e-113	70.0
WP_162681714.1\|1303073_1303421_-	fluoride efflux transporter CrcB	NA	NA	NA	NA
WP_162683019.1\|1303417_1303783_-	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	2.2e-27	52.5
WP_162681715.1\|1303815_1304118_-	hypothetical protein	NA	NA	NA	NA
WP_162681716.1\|1304270_1304981_+	transaldolase	M1PR54	Cyanophage	1.2e-21	39.0
WP_162681717.1\|1305157_1305607_+	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	3.1e-07	32.7
WP_162681718.1\|1305609_1306041_-	hypothetical protein	NA	NA	NA	NA
WP_162683020.1\|1306043_1306532_-	sigma-70 family RNA polymerase sigma factor	A0A2H4PQT5	Staphylococcus_phage	2.4e-18	36.0
WP_014613594.1\|1306729_1306954_+	hypothetical protein	NA	NA	NA	NA
WP_162681719.1\|1307110_1307974_+	autolysin	A0A1W6JQU5	Staphylococcus_phage	4.9e-38	42.2
WP_162681720.1\|1308379_1309948_+	FAD-dependent oxidoreductase	A0A2H4PQX2	Staphylococcus_phage	2.6e-13	60.3
WP_162681721.1\|1310402_1311449_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	2.0e-110	56.4
WP_162681722.1\|1311453_1312083_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.1e-63	58.6
WP_162681723.1\|1312096_1313278_+	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	3.7e-153	66.4
WP_162681724.1\|1313292_1313760_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.6e-51	64.3
WP_162681725.1\|1314418_1315405_-	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	2.9e-119	65.2

DBSCAN-SWA_9

1319682 : 1327410

Staphylococcus_phage(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_162681730.1\|1319682_1320246_-	methyltransferase domain-containing protein	A0A2H4PQV0	Staphylococcus_phage	2.4e-57	57.8
WP_162681731.1\|1320242_1321196_-	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	5.8e-64	81.2
WP_162681732.1\|1321342_1322524_+	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	5.2e-131	61.5
WP_162681733.1\|1322835_1325247_+\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	81.5
WP_162681734.1\|1325273_1325585_+	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	1.0e-33	68.9
WP_162681735.1\|1326153_1327410_-	NAD(P)/FAD-dependent oxidoreductase	A0A2H4PQX1	Staphylococcus_phage	3.1e-33	69.6

DBSCAN-SWA_10

1448713 : 1458056

uncultured_Mediterranean_phage(66.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_162681829.1\|1448713_1449853_+\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	1.4e-88	45.5
WP_162681830.1\|1449869_1450133_+	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	1.2e-06	42.9
WP_162681831.1\|1450274_1452554_+	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	2.5e-28	31.6
WP_162681832.1\|1452670_1454956_+	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	3.5e-67	29.5
WP_096545126.1\|1454967_1455486_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	8.9e-27	48.0
WP_162681833.1\|1455866_1458056_+	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	A0A1B1IUF0	uncultured_Mediterranean_phage	5.0e-10	35.8

DBSCAN-SWA_11

1600643 : 1609069

uncultured_Mediterranean_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_162681961.1\|1600643_1601372_+	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	2.2e-10	32.7
WP_162681962.1\|1601361_1601904_+	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	9.7e-08	41.7
WP_162681963.1\|1601904_1602651_+	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_026066968.1\|1602762_1603485_+	response regulator transcription factor	W8CYM9	Bacillus_phage	5.4e-46	41.4
WP_162681964.1\|1603471_1605229_+	cell wall metabolism sensor histidine kinase WalK	A0A1V0SGX0	Hokovirus	2.2e-16	22.8
WP_162681965.1\|1605590_1606136_+	ECF transporter S component	NA	NA	NA	NA
WP_014613875.1\|1606401_1606650_-	ferredoxin	A0A127AYY7	Bacillus_phage	2.3e-17	53.3
WP_162681966.1\|1606752_1607700_+	hypothetical protein	NA	NA	NA	NA
WP_162681967.1\|1607692_1609069_+	ATP-dependent DNA helicase RecQ	J2YAJ8	Acanthamoeba_polyphaga_lentillevirus	1.1e-55	34.5

DBSCAN-SWA_12

2509777 : 2572138

Bodo_saltans_virus(25.0%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_162682664.1\|2509777_2510500_+\|protease	trypsin-like serine protease	NA	NA	NA	NA
WP_162682665.1\|2510847_2511561_+\|protease	trypsin-like serine protease	NA	NA	NA	NA
WP_162682666.1\|2511992_2512754_+	trypsin-like peptidase domain-containing protein	NA	NA	NA	NA
WP_162682667.1\|2513151_2513859_+	trypsin-like peptidase domain-containing protein	NA	NA	NA	NA
WP_162682668.1\|2514234_2514939_+	trypsin-like peptidase domain-containing protein	NA	NA	NA	NA
WP_162682669.1\|2515056_2515212_+	hypothetical protein	NA	NA	NA	NA
WP_162682670.1\|2515261_2515972_+	trypsin-like peptidase domain-containing protein	NA	NA	NA	NA
WP_162682671.1\|2516306_2517848_-	SLC13/DASS family transporter	NA	NA	NA	NA
WP_162682672.1\|2518092_2518554_-	threonine/serine exporter	NA	NA	NA	NA
WP_162683061.1\|2518566_2519280_-	threonine/serine exporter family protein	NA	NA	NA	NA
WP_162682673.1\|2519557_2519827_+	AbrB family transcriptional regulator	NA	NA	NA	NA
WP_162682674.1\|2520066_2520822_-	heme-dependent peroxidase	NA	NA	NA	NA
WP_162682675.1\|2520989_2521979_+	phosphate acetyltransferase	NA	NA	NA	NA
WP_162682676.1\|2521978_2522815_+	lipoate--protein ligase family protein	NA	NA	NA	NA
WP_162682677.1\|2522973_2523378_-	arsenate reductase (thioredoxin)	A0A2H4PQT9	Staphylococcus_phage	1.7e-57	80.0
WP_162682678.1\|2525672_2527526_-	DHA2 family efflux MFS transporter permease subunit	NA	NA	NA	NA
WP_162682679.1\|2527542_2528190_-	HlyD family secretion protein	NA	NA	NA	NA
WP_162682680.1\|2528316_2528880_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_162682681.1\|2528984_2530154_+	DUF418 domain-containing protein	NA	NA	NA	NA
WP_162682682.1\|2530390_2530951_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_162682683.1\|2531182_2532634_+	APC family permease	NA	NA	NA	NA
WP_162682684.1\|2533317_2533680_-	DUF423 domain-containing protein	NA	NA	NA	NA
WP_162682685.1\|2533707_2534031_-	YwdI family protein	NA	NA	NA	NA
WP_162683062.1\|2534023_2534692_-	uracil-DNA glycosylase	A0A0R5YU95	Harp_seal_herpesvirus	5.7e-42	45.0
WP_162682686.1\|2534880_2535711_+	bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase	NA	NA	NA	NA
WP_162682687.1\|2535964_2538514_-	protein kinase/lanthionine synthetase C family protein	A0A1V0SGY7	Hokovirus	3.0e-06	30.5
WP_162682688.1\|2538514_2540122_-	ABC transporter ATP-binding protein	A0A076FI99	Aureococcus_anophage	1.1e-22	22.1
WP_162682689.1\|2540864_2541125_-	hypothetical protein	NA	NA	NA	NA
WP_162682690.1\|2541124_2541496_-	hypothetical protein	NA	NA	NA	NA
WP_162682691.1\|2541464_2542610_-	thiolase family protein	NA	NA	NA	NA
WP_162683063.1\|2542606_2543899_-	long-chain fatty acid--CoA ligase	NA	NA	NA	NA
WP_162682692.1\|2544187_2544874_-	2,3-diphosphoglycerate-dependent phosphoglycerate mutase	NA	NA	NA	NA
WP_162682693.1\|2545119_2546589_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2H4UUX5	Bodo_saltans_virus	7.2e-13	21.8
WP_162682694.1\|2546594_2547827_-	MFS transporter	NA	NA	NA	NA
WP_162682695.1\|2547846_2550303_-	hypothetical protein	NA	NA	NA	NA
WP_162682696.1\|2550367_2550541_-	hypothetical protein	NA	NA	NA	NA
WP_162682697.1\|2551671_2552529_-	oxidoreductase	NA	NA	NA	NA
WP_162682698.1\|2552953_2553682_-\|protease	M48 family metalloprotease	NA	NA	NA	NA
WP_162682699.1\|2553694_2554162_-	stage II sporulation protein M	NA	NA	NA	NA
WP_162682700.1\|2554728_2555010_-	hypothetical protein	NA	NA	NA	NA
WP_162682701.1\|2555575_2556124_-	6-phospho-3-hexuloisomerase	NA	NA	NA	NA
WP_162682702.1\|2556125_2556764_-	3-hexulose-6-phosphate synthase	NA	NA	NA	NA
WP_162682703.1\|2556860_2557595_-	glucosamine-6-phosphate deaminase	NA	NA	NA	NA
WP_162682704.1\|2557600_2558275_-	N-acetylmannosamine-6-phosphate 2-epimerase	NA	NA	NA	NA
WP_162683064.1\|2558275_2559814_-	PTS transporter subunit EIIC	NA	NA	NA	NA
WP_162682705.1\|2559933_2560779_+	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
WP_162682706.1\|2560858_2561218_+	YojF family protein	NA	NA	NA	NA
WP_162683065.1\|2561236_2561914_+	bacillithiol biosynthesis deacetylase BshB2	NA	NA	NA	NA
WP_162682707.1\|2561959_2562838_+	GTP cyclohydrolase I FolE2	NA	NA	NA	NA
WP_162682708.1\|2563197_2564406_-	MFS transporter	NA	NA	NA	NA
WP_162682709.1\|2564823_2565876_-	ATP-grasp domain-containing protein	NA	NA	NA	NA
WP_162682710.1\|2566031_2566598_-	adenylate cyclase	NA	NA	NA	NA
WP_162682711.1\|2566597_2567002_-	hypothetical protein	NA	NA	NA	NA
WP_162683066.1\|2566989_2567427_-	radical SAM protein	NA	NA	NA	NA
WP_162682712.1\|2567360_2567534_-	SHP2/SHP3 family peptide pheromone	NA	NA	NA	NA
WP_162682713.1\|2567614_2568469_+	Rgg/GadR/MutR family transcriptional regulator	NA	NA	NA	NA
WP_162682714.1\|2568489_2569239_-\|transposase	transposase	NA	NA	NA	NA
WP_162682715.1\|2569517_2570258_-	HAD family hydrolase	A0A2H4UUK2	Bodo_saltans_virus	1.4e-09	25.2
WP_162680810.1\|2570575_2570980_+\|transposase	IS200/IS605 family transposase	A0A286QN76	Streptococcus_phage	1.1e-53	76.2
WP_162681057.1\|2570995_2572138_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A288TXV8	Enterococcus_phage	2.4e-197	89.4

DBSCAN-SWA_13

2580461 : 2621225

Staphylococcus_phage(73.53%)

tail,integrase,terminase,head,plate,holin

attL 2577461:2577510|attR 2618351:2618400

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2577461:2577510	attL	NA	NA	NA	NA
WP_162682726.1\|2580461_2581409_-	N-acetylmuramoyl-L-alanine amidase	A0A1P8CMK9	Staphylococcus_phage	3.5e-85	52.4
WP_162682727.1\|2581427_2581856_-\|holin	phage holin family protein	A0A1S6KVE0	Staphylococcus_phage	4.8e-42	60.9
WP_162682728.1\|2581867_2583790_-	SGNH/GDSL hydrolase family protein	I6P9N4	Staphylococcus_phage	3.1e-117	45.4
WP_162682729.1\|2583913_2585185_-\|plate	BppU family phage baseplate upper protein	A0A1J0MFK8	Staphylococcus_phage	6.9e-206	83.5
WP_162682730.1\|2585201_2586221_-	SGNH/GDSL hydrolase family protein	A0A1J0MFI8	Staphylococcus_phage	1.1e-142	74.4
WP_162682731.1\|2586231_2586873_-	hypothetical protein	A0A1J0MFH9	Staphylococcus_phage	1.3e-38	51.7
WP_162682732.1\|2586876_2588292_-	hypothetical protein	A0A1J0MFL4	Staphylococcus_phage	5.9e-121	46.0
WP_162682733.1\|2588306_2589227_-\|tail	phage tail family protein	Q4ZE20	Staphylococcus_virus	6.1e-79	47.1
WP_162682734.1\|2589239_2592176_-\|tail	phage tail protein	Q4ZC60	Staphylococcus_virus	4.0e-116	47.5
WP_162682735.1\|2592188_2592536_-	hypothetical protein	Q4ZE25	Staphylococcus_virus	2.4e-20	48.7
WP_162681685.1\|2592604_2592958_-\|tail	phage tail protein	A0A1J0MFH0	Staphylococcus_phage	6.9e-23	46.2
WP_162681684.1\|2593011_2593560_-\|tail	phage major tail protein, TP901-1 family	A0EWT6	Staphylococcus_virus	7.0e-30	44.5
WP_162681683.1\|2593577_2593967_-	hypothetical protein	NA	NA	NA	NA
WP_162683012.1\|2593972_2594320_-	hypothetical protein	H9A0N6	Staphylococcus_phage	4.3e-25	51.7
WP_162681682.1\|2594300_2594597_-	hypothetical protein	NA	NA	NA	NA
WP_162681681.1\|2594620_2594944_-\|head,tail	phage head-tail connector protein	Q4ZE31	Staphylococcus_virus	6.1e-18	47.9
WP_162682736.1\|2595907_2596492_-	DUF4355 domain-containing protein	NA	NA	NA	NA
WP_162682737.1\|2596812_2598363_-\|head	head protein	A0A1J0MF61	Staphylococcus_phage	3.9e-102	57.6
WP_162682738.1\|2599767_2601018_-\|terminase	PBSX family phage terminase large subunit	A0A059T7K2	Staphylococcus_phage	3.9e-145	60.9
WP_162682739.1\|2601010_2601451_-\|terminase	terminase small subunit	H9A0M8	Staphylococcus_phage	6.4e-42	71.5
WP_162682740.1\|2601523_2601859_-	hypothetical protein	NA	NA	NA	NA
WP_162682741.1\|2602085_2602502_-	transcriptional regulator	I1W651	Staphylococcus_phage	9.0e-46	65.7
WP_162682742.1\|2602523_2603897_-	DEAD/DEAH box helicase	A7TWI6	Staphylococcus_phage	2.2e-221	80.7
WP_162682743.1\|2603871_2604168_-	VRR-NUC domain-containing protein	Q4ZD25	Staphylococcus_phage	4.3e-34	65.3
WP_162683067.1\|2604506_2605529_-	hypothetical protein	A0A0K1LKN1	Staphylococcus_phage	6.6e-167	79.7
WP_162682744.1\|2607010_2607205_-	hypothetical protein	NA	NA	NA	NA
WP_162682745.1\|2607247_2607547_-	hypothetical protein	I6SB84	Staphylococcus_virus	2.7e-44	87.9
WP_162682746.1\|2607530_2607689_-	hypothetical protein	NA	NA	NA	NA
WP_162682747.1\|2607672_2607873_-	hypothetical protein	A0A2H4J5D7	uncultured_Caudovirales_phage	7.2e-09	47.5
WP_162682748.1\|2607887_2608058_-	hypothetical protein	NA	NA	NA	NA
WP_162682749.1\|2608058_2608256_-	hypothetical protein	NA	NA	NA	NA
WP_162682750.1\|2608270_2608453_-	hypothetical protein	NA	NA	NA	NA
WP_162682751.1\|2608705_2608969_-	DUF3310 domain-containing protein	A0A0D4DCF1	Staphylococcus_phage	2.4e-28	77.2
WP_162682752.1\|2608980_2609478_-	hypothetical protein	NA	NA	NA	NA
WP_162682753.1\|2609493_2611446_-	DNA polymerase	Q4ZD45	Staphylococcus_phage	0.0e+00	86.2
WP_162682754.1\|2611509_2612061_-	DUF2815 family protein	Q4ZD46	Staphylococcus_phage	5.8e-85	87.0
WP_162682755.1\|2612082_2613249_-	DUF2800 domain-containing protein	Q4ZD47	Staphylococcus_phage	1.3e-166	73.2
WP_162682756.1\|2613245_2613581_-	hypothetical protein	Q4ZD48	Staphylococcus_phage	3.2e-17	44.5
WP_162682757.1\|2613661_2613943_-	DUF2482 family protein	NA	NA	NA	NA
WP_162682758.1\|2614149_2614359_-	hypothetical protein	A0A1W6JQ31	Staphylococcus_phage	1.7e-21	68.1
WP_162682759.1\|2614492_2614723_-	hypothetical protein	NA	NA	NA	NA
WP_162682760.1\|2614742_2614967_-	helix-turn-helix transcriptional regulator	Q9MBT3	Staphylococcus_prophage	2.2e-27	80.8
WP_162682761.1\|2615136_2615448_+	helix-turn-helix transcriptional regulator	G4KNM8	Staphylococcus_phage	1.6e-31	66.7
WP_162682762.1\|2615556_2616525_+	hypothetical protein	A0A1Q1PVZ4	Staphylococcus_phage	2.1e-114	65.4
WP_162682763.1\|2616507_2616684_-	hypothetical protein	NA	NA	NA	NA
WP_162682764.1\|2616799_2617846_+\|integrase	site-specific integrase	M9NTA3	Staphylococcus_phage	5.2e-151	74.8
WP_162680750.1\|2617826_2618030_-	hypothetical protein	NA	NA	NA	NA
WP_162682765.1\|2618397_2619480_-	branched-chain amino acid aminotransferase	NA	NA	NA	NA
2618351:2618400	attR	NA	NA	NA	NA
WP_162682766.1\|2619605_2621225_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	7.3e-59	31.8

DBSCAN-SWA_14

2793288 : 2833311

Staphylococcus_phage(31.25%)

transposase,tRNA,integrase,bacteriocin,protease

attL 2817528:2817543|attR 2834532:2834547

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_162682872.1\|2793288_2793864_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_162682873.1\|2794305_2795193_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	6.0e-31	43.1
WP_162682874.1\|2795194_2795947_+	amino acid transporter	NA	NA	NA	NA
WP_162682875.1\|2796112_2796874_-	DMT family transporter	NA	NA	NA	NA
WP_162683076.1\|2796994_2798140_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	D9J0Y9	Brochothrix_phage	4.5e-156	72.8
WP_162682876.1\|2798151_2798346_-	hypothetical protein	NA	NA	NA	NA
WP_162682877.1\|2798565_2798805_-	hypothetical protein	NA	NA	NA	NA
WP_162683077.1\|2799491_2800337_+	alpha/beta hydrolase	A0A1P8CWK6	Bacillus_phage	3.5e-44	46.6
WP_162682878.1\|2800445_2801522_-\|tRNA	arginine--tRNA ligase	A0A2I2L3K1	Orpheovirus	2.8e-38	29.3
WP_162682879.1\|2802499_2803996_-	ATP-dependent DNA helicase RecG	NA	NA	NA	NA
WP_162682880.1\|2804690_2806970_-\|transposase	IS1182 family transposase	A0ZS58	Staphylococcus_virus	1.8e-151	52.2
WP_162680888.1\|2807235_2808444_-\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	8.4e-68	40.2
WP_162682881.1\|2808995_2809847_-	Abi family protein	NA	NA	NA	NA
WP_162682882.1\|2811813_2812086_-	hypothetical protein	NA	NA	NA	NA
WP_162682883.1\|2812095_2812332_-	hypothetical protein	A0A1W6JPE1	Staphylococcus_phage	1.3e-09	44.7
WP_019168684.1\|2812510_2812855_-	hypothetical protein	Q4ZE66	Staphylococcus_phage	1.1e-28	55.8
WP_162682884.1\|2814901_2815774_-	mobile element-associated protein	A0A1W6JQL5	Staphylococcus_phage	2.2e-46	38.4
WP_162682885.1\|2815788_2816103_-	DUF1474 family protein	A0A1W6JQH0	Staphylococcus_phage	2.3e-17	53.8
WP_162682886.1\|2816108_2816456_-	pathogenicity island protein	A0A2H4JBF1	uncultured_Caudovirales_phage	5.2e-31	52.2
WP_162682887.1\|2816469_2816616_-	hypothetical protein	NA	NA	NA	NA
WP_162682888.1\|2816690_2816957_-	DNA-binding protein	NA	NA	NA	NA
WP_162682889.1\|2816999_2817200_-	hypothetical protein	NA	NA	NA	NA
WP_162682890.1\|2817198_2818041_+	helix-turn-helix transcriptional regulator	Q4ZC20	Staphylococcus_virus	7.2e-10	48.5
2817528:2817543	attL	NA	NA	NA	NA
WP_162682891.1\|2818141_2819278_+\|integrase	site-specific integrase	A0A1S5S7K9	Streptococcus_phage	6.9e-72	40.3
WP_162682892.1\|2819371_2820913_-	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	6.1e-23	31.6
WP_162683078.1\|2820935_2822402_-	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	6.1e-97	41.4
WP_162682893.1\|2822439_2823708_-	purine permease	NA	NA	NA	NA
WP_162682894.1\|2823704_2824289_-	xanthine phosphoribosyltransferase	NA	NA	NA	NA
WP_162682895.1\|2824751_2825174_+	general stress protein	NA	NA	NA	NA
WP_162682896.1\|2825371_2826046_+	hypothetical protein	NA	NA	NA	NA
WP_014614902.1\|2826159_2826759_+	hypothetical protein	NA	NA	NA	NA
WP_162682897.1\|2827034_2828141_+	glycine oxidase ThiO	NA	NA	NA	NA
WP_162682898.1\|2828215_2829607_+	cation:dicarboxylase symporter family transporter	NA	NA	NA	NA
WP_162682899.1\|2830077_2830734_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	8.4e-22	36.2
WP_162682900.1\|2830730_2831060_-	YxeA family protein	NA	NA	NA	NA
WP_162682901.1\|2831063_2833031_-	DUF1430 domain-containing protein	NA	NA	NA	NA
WP_162683079.1\|2833056_2833311_-\|bacteriocin	lactococcin 972 family bacteriocin	NA	NA	NA	NA
2834532:2834547	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP048279

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection