CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP048387	Spiroplasma sp. TIUS-1 chromosome, complete genome	5 crisprs	DEDDh	0	7	0	0

Cas Category Instructions

Results visualization

1. NZ_CP048387

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP048387_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP048387_1

193656-193996

Orphan

Consensus_repeat	Method
TAATTTTAATCAAGATATTGGAAATTGAGATACATCAAGTG	PILER-CR

4 spacers

The CRISPR arrays of NZ_CP048387_1

>merge|NZ_CP048387|1|193656-193996|PILER-CR
TAATTTTAATCAAGATATTGGAAATTGAGATACGTCAAGTGTAACAGATATGAGTTCTATGTTTTATTGAGCTACTAATTTTAATAAAGATATTGGAAATTGAGATACATCTAAAGTAAGAAAAATGGATTCAATGTTTAGAGGTGCTCATAGTTTTAATCAAGATATTGGAAATTGAGATACGTCAAGTGTATGAAATTTAGGTGTTATGTTTTATGATGCAGTTAATTTTAATCAAGATATTGGAAATTGAGATACATCAGGTGCAACATATATGAGTTATATGTTTTATGGAGCCACTAATTTTAATCAAGATATTGGAAATTGAGATACATCAAATG

>NZ_CP048387|1|1|193656-193996|PILER-CR
TAATTTTAATCAAGATATTGGAAATTGAGATACGTCAAGTG	TAACAGATATGAGTTCTATGTTTTATTGAGCTAC
TAATTTTAATAAAGATATTGGAAATTGAGATACATCTAAAG	TAAGAAAAATGGATTCAATGTTTAGAGGTGCTCATAGTT
TTAATCAAGATATTGGAAATTGAGATACGTCAAGTGTATGA	AATTTAGGTGTTATGTTTTATGATGCAGTTAATT
TTAATCAAGATATTGGAAATTGAGATACATCAGGTGCAACA	TATATGAGTTATATGTTTTATGGAGCCACTAATT
TTAATCAAGATATTGGAAATTGAGATACATCAAATG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP048387.1\|WP_162649380.1\|177921_182199_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376899
NZ_CP048387.1\|WP_162649397.1\|200924_201257_+\|PTS-lactose/cellobiose-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|376749
NZ_CP048387.1\|WP_162649379.1\|177193_177886_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048387.1\|WP_162649383.1\|184171_186763_+\|PTS-transporter-subunit-EIIA	unknown	unknown	gnl\|CDD\|224218
NZ_CP048387.1\|WP_162649390.1\|195375_195909_-\|acetyltransferase	unknown	unknown	unknown
NZ_CP048387.1\|WP_162649388.1\|194577_195336_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048387.1\|WP_162649396.1\|199073_200879_+\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
NZ_CP048387.1\|WP_162649382.1\|183262_184069_+\|MurR/RpiR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224651
NZ_CP048387.1\|WP_162649378.1\|176719_177121_+\|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-ATPase-subunit-type-1-TsaE	unknown	unknown	gnl\|CDD\|376771
NZ_CP048387.1\|WP_162649398.1\|201314_201938_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048387.1\|WP_162649392.1\|197429_198368_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|378820
NZ_CP048387.1\|WP_162649391.1\|195991_197419_+\|proline--tRNA-ligase	unknown	unknown	gnl\|CDD\|236327
NZ_CP048387.1\|WP_162649384.1\|186952_187501_+\|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-dimerization-subunit-type-1-TsaB	unknown	unknown	gnl\|CDD\|224135
NZ_CP048387.1\|WP_162649399.1\|202239_202551_+\|PTS-sugar-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|99906
NZ_CP048387.1\|WP_162649386.1\|191991_192684_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048387.1\|WP_162650031.1\|190795_191989_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|213216
NZ_CP048387.1\|WP_162649385.1\|187537_189541_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274414
NZ_CP048387.1\|WP_162649400.1\|202587_204771_+\|PTS-sugar-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|224372
NZ_CP048387.1\|WP_162649394.1\|198443_198962_+\|DUF402-domain-containing-protein	unknown	unknown	gnl\|CDD\|184219
NZ_CP048387.1\|WP_162649381.1\|182229_183150_-\|mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|224399

Protein	Function_ID	Function_description	E-value
NZ_CP048387.1\|WP_162649380.1\|177921_182199_+\|ABC-transporter-permease	gnl\|CDD\|376899	pfam02687, FtsX, FtsX-like permease family. This is a family of predicted permeases and hypothetical transmembrane proteins. Buchnera aphidicola LolC has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both LolC and Streptococcus cristatus TptD have been shown to require ATP. This region contains three transmembrane helices.	1.5681e-09
NZ_CP048387.1\|WP_162649397.1\|200924_201257_+\|PTS-lactose/cellobiose-transporter-subunit-IIA	gnl\|CDD\|376749	pfam02255, PTS_IIA, PTS system, Lactose/Cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. The lactose/cellobiose-specific family are one of four structurally and functionally distinct group IIA PTS system enzymes. This family of proteins normally function as a homotrimer, stabilized by a centrally located metal ion. Separation into subunits is thought to occur after phosphorylation.	6.54073e-30
NZ_CP048387.1\|WP_162649383.1\|184171_186763_+\|PTS-transporter-subunit-EIIA	gnl\|CDD\|224218	COG1299, FruA, Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism].	5.07244e-83
NZ_CP048387.1\|WP_162649396.1\|199073_200879_+\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NZ_CP048387.1\|WP_162649382.1\|183262_184069_+\|MurR/RpiR-family-transcriptional-regulator	gnl\|CDD\|224651	COG1737, RpiR, Transcriptional regulators [Transcription].	5.07418e-38
NZ_CP048387.1\|WP_162649392.1\|197429_198368_+\|alpha/beta-hydrolase	gnl\|CDD\|378820	pfam12146, Hydrolase_4, Serine aminopeptidase, S33. This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.	5.04586e-50
NZ_CP048387.1\|WP_162649394.1\|198443_198962_+\|DUF402-domain-containing-protein	gnl\|CDD\|184219	PRK13662, PRK13662, hypothetical protein; Provisional.	9.14417e-59
NZ_CP048387.1\|WP_162649391.1\|195991_197419_+\|proline--tRNA-ligase	gnl\|CDD\|236327	PRK08661, PRK08661, prolyl-tRNA synthetase; Provisional.	0
NZ_CP048387.1\|WP_162649384.1\|186952_187501_+\|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-dimerization-subunit-type-1-TsaB	gnl\|CDD\|224135	COG1214, COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones].	1.17178e-28
NZ_CP048387.1\|WP_162649378.1\|176719_177121_+\|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-ATPase-subunit-type-1-TsaE	gnl\|CDD\|376771	pfam02367, TsaE, Threonylcarbamoyl adenosine biosynthesis protein TsaE. This family of proteins is involved in the synthesis of threonylcarbamoyl adenosine (t(6)A).	8.18655e-40
NZ_CP048387.1\|WP_162650031.1\|190795_191989_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|213216	cd03249, ABC_MTABC3_MDL1_MDL2, ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins. MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.	9.76138e-113
NZ_CP048387.1\|WP_162649399.1\|202239_202551_+\|PTS-sugar-transporter-subunit-IIB	gnl\|CDD\|99906	cd05564, PTS_IIB_chitobiose_lichenan, PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N,N-diacetylchitobiose-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane channel IIC domain. In the chitobiose system, these subunits are expressed as separate proteins from chbA, chbB, and chbC of the chb operon (formerly the cel (cellulose) operon). In the lichenan system, these subunits are expressed from licA, licB, and licC of the lic operon. The lic operon of Bacillus subtilis is required for the transport and degradation of oligomeric beta-glucosides, which are produced by extracellular enzymes on substrates such as lichenan or barley glucan. The lic operon is transcribed from a gammaA-dependent promoter and is inducible by lichenan, lichenan hydrolysate, and cellobiose. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include chitobiose/lichenan, ascorbate, lactose, galactitol, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	7.78712e-31
NZ_CP048387.1\|WP_162649385.1\|187537_189541_-\|hypothetical-protein	gnl\|CDD\|274414	TIGR03062, hypothetical_protein_lp_1332, YhgE/Pip C-terminal domain. This family contains the C-terminal domain of a family of multiple membrane-spanning proteins of Gram-positive bacteria. One member was shown to be a host protein essential for phage infection, so many members of this family are called "phage infection protein". A separate model, TIGR03061, represents the conserved N-terminal domain. The domains are separated by regions highly variable in both length and sequence, often containing extended heptad repeats as described in model TIGR03057.	3.30898e-19
NZ_CP048387.1\|WP_162649400.1\|202587_204771_+\|PTS-sugar-transporter-subunit-IIC	gnl\|CDD\|224372	COG1455, CelB, Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism].	6.69701e-54
NZ_CP048387.1\|WP_162649381.1\|182229_183150_-\|mannose-6-phosphate-isomerase	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	3.67063e-71

>NZ_CP048387.1|WP_162649386.1|191991_192684_+|hypothetical-protein
MKLKLVDMFSPSKNWKTTLILVFIVSIITIGSSLFMGFRYSNDLGDVENFWLIAKYEHTFSYIRYIWNHYENENSLDVIFADTKINKSAQVFALASDYLLISLICGFIVIIPFVINHFRLVNIVTKNRRILNSSIVLVSSLGLLLTTFHYWIAYFQTIPILNEKEWMGTGNWFPTWQTILQLTVILFGVTMVVAMSIYNVVVEAKTRYISISQKYALENKKPEPDNILSE
>NZ_CP048387.1|WP_162650031.1|190795_191989_+|ATP-binding-cassette-domain-containing-protein
MKKSIVERSEHDSSITEKISLIRLVKSSGNWESEVKENNIETEKNNKTNKKLNLAISVIPGIIIGAMGCLTLSSMVFGVFIFGDNTQKLITVFSSFTAGIFVMVTPIFQLNTILQSINVTNKSSQNIGDIVSNENKIKKIKYPKFLTKNVIEKIEFNDVSFAYPSRPDEQVIKNLSIVLEKGKSYAFVGPSGSGKSTVTRLLMRFYEDYSGKIIINNKLEVRDISLKNWMDNIGYVDQEPQILSATVFENLRYVKKDATDEEIIEACKKAKIHNLIENMENGYETFLKERGKQLSGGQQQRLVIARMFLKNPSLIILDEATSALDNLVEKEISLELEKLIEGKTTIAIAHRLSTIKNYDKIFVLDTNKKIVQEGTFNQLIKVPGLFKELYEVGKEKE
>NZ_CP048387.1|WP_162649385.1|187537_189541_-|hypothetical-protein
MKNWWLGVQAEFGSRIGSSKKRIIKFIGISLVPILYAVVCVLAFWNPIPGIGKAPTAIIDTEQKVYVGTNQKFEVLGKNLLKESNESELSEAYRVNTKLSILPHIGVLTDDIESLKEAIVKDENKEVTKDDFTGSLSKTIDMSNVNYVYAVNTWTLMEANLLNHKGGNKYEAKKAISEEEIFFSNITHLQGKEAEDNYKNPKYYLQMKFDDGLASGLVTKIGLMLQGKLFDNPAKQENLKIWTTFENNFIFGYYLKTLNSFRSAIPSLILEKVVDNIKLEGISKGELKTKLEVARDFAVSQANNENSITAPIWTKIANSLNEAITLLESVGGEIDAKVTKIIQELIKDVINIVGLGGQTNNIIDVEIQGLKNGNNAIAIYGIGLGEFFILIGMFVGTLMQTFVYDRAKRVKKLTNTQWYLSKTFLMWTTGMLQVGLLVLALTAAGWWIIGALALVKLWLWLMVVETVFVITIQALWFSLKDETIGKFLVVVYMVLNLSSGWGTFPAFMQFGFFNAISYITEFKYALHGMTSIIYSNGDNALFMFKQLGVLLIFMAVLITIGLIFSRNRDKEMYFGSYRGKQVYDCLQSLGKTELADEFRTKRNNGKSFKYNWKVLGKEPMKDLVLEVRKKYPFEGQFKWFKNKERDEVLKPNYSDDDVISRNDDVTV
>NZ_CP048387.1|WP_162649384.1|186952_187501_+|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-dimerization-subunit-type-1-TsaB
MKSLFIDTTNNKIVFIYLHDNKLIDSIVVDAKNKISEIFDDELKMFLAKQKTELNEISEFYVTKGPGTFTGVRIGLSIVKTIWTINKDIKVYSINTMQLMAGKSKVSVAIDARGGKHFFASNTNGIIANNLEIVLNEKLPKENIITNLDNIDYVKNFSEVRDKFILETDINNFNPIYIKNAI
>NZ_CP048387.1|WP_162649383.1|184171_186763_+|PTS-transporter-subunit-EIIA
MNKDILNSKHIFLDVELNSQDEVFDFLAKKAKELGIVTSDKALVAGFKKRESESSTGFEDGFAIPHARIVEANQAACLVVKLKKAIDWNSMDGKPTQYLFSLIVPDGKGDEHMSILSDIATKLIIEEFKSAIINAKTQEDVLKAFNVKKVESKQTTPTEGGLKIVAISACTVGIAHTYMAEEKLIQEGKKMGHQVRVETHGSKGIGTPLTKKEIDEADIVIFAVDVNVDNSRFVGKKFYKVPVAKAIKDTQKVINIAIKDGAPLAGAAKFETSGKVTGERQTVMSHILAGISYMIPVIVLGGICLAFSLGIAKAVWGPTAGTDGSAWIVAGDFAKGWLVQVKDGVIIDGSGVQWVEGMTLPTLAEGAVWGLSDGSYIRSFNGTDLNYTADFLKTLPVSPWGPLAVMDKIGGAAFTLMIPILAGFIANSIGGRAAIGPAMVGAFIGNNAAMFMTFGGMNSADMVPTGFIGAIIAGLLVGYAVSWINTWNVPKSLRAAMPIFFIPLITGILISMLFIYVIGGPIGWVMFQFSDAIKSAYESKAGAGVGIALGILIGAMAGFDMGGPINKIAFVTCSALITMGIYEPMGTMAAAIPVAPIGMGLTSLLFGRFFNSDERGMGSAAVIMGSIGISEGAIPFAIRDPKRAIASNVVGSAVAGAIAGGFMVQNMAAHGGPIVAILGAVPYGVDTLYYFIAAAAGIATTVLVYGFWLTADSGAIASVKEAHVAKLVDLSNEKSSKIDDIKEEIKVLKLSKNVSAIDVKKSEIAKVKDAYKADVEKAKAAYAKVKPEEKALMTTKKEDVKSFTSTLKANYTTAMASIKSDTLKGDTKTDAIEKAKLEKANKYREFQEGIRGELVSKYLAAAS
>NZ_CP048387.1|WP_162649382.1|183262_184069_+|MurR/RpiR-family-transcriptional-regulator
MILEKLNKHAKYDSSIEGKISKTIINYISANKEFKLGIIKLSNDSGTSQPSVTRFVTKIIGTKNYKEFINVLNAEIKTYFESNYDQNNLNDNSAQICQDIKETLLHISDEEIKKSTDLIMNAERINVIAIGGSATIKVEIEHKLSKIGMNLMSSSDWHHQLINVNFMSSNDVIIAISYSGDKHEVTQILKKAKEKNVKIILITGPFSSYSRDVADIVFEAKSTDAKFRSFSFTSRLCGMAIWEVIFKSIIASEAISSDVIEQWRWDQK
>NZ_CP048387.1|WP_162649381.1|182229_183150_-|mannose-6-phosphate-isomerase
MNIFKINPSFSERVWGGQKLNSMGYNIPKDKKIGEAWVISAHENGMGFAAEGIWKGKSVKEIFESNRTLFGNVQGSFPLLVKILTPEQNLSVQVHPNDELAKKHNDFGKPESWYVLDCPDNAKLIYGHTAKTKKELAEMIEKDQWKELLVEVPVKKGDFLYVPPGKIHAVTPNVVVYELQRSSDITYRVYDYGRLENGKPRKLHIEDTIVSTTVPDTNIAIINNATKLIHSNEYFSLYLYETSKETKPFKLIEKTGWLQITVIEGTGKINGVDYILGDCSIACDLNESSSLDITGNLKVLISWIKL
>NZ_CP048387.1|WP_162649380.1|177921_182199_+|ABC-transporter-permease
MSLRSIRLLLRNGFRNAKRTKMQIIGLTLLIMLISLLTSISAHTKETVIGGSERLKIESKQNDFIFSINPEYRLQQPEDKNLPENQTLVQQYYVNELSQKDKYDFSWSRTEGRIFSNVTNDGEKLNIKALAKTNVSGEEEFTNDINVDSLVISQGRNFSASTEMARREIIINENFAKANNLKLNDIIRVQLDKQGDTLNVKDNPEVRKNLEGVTDIHTQLPEQYKKYYWMQIVGFGTSADFLSPIIDETSIIPNSKTNMVAYVHPSHFGLVVDKDSSFYLQSMSESSLMPTSSFGNEIYYSARFNSTHHDLEVIDKEFKSITNNNAGNKKVVYGINDDEYKFVQRTSLLDQIVVGYKAGITVLLVIVMGISLFALVIMIKKQVEIYRMQLGILKAMGLRKTEIVNNFVAIPMISGAMGVILGYGLSFVISPLIMDMFSSFFSLTFTLSSFSVISLVNSIFTTWFGLLLITFLCTYLTIKDSPSKLLAKMNPSSIGWIQMKIKSIGSSRKKFEPRLRLAVVSTSWQKYLGTLLTILVSTFILSITVITPRILETNKTKAFDGLNYQNKVEYIDPIAANPLSFFKTYNPDKNNKEDNWGFPTQENASDKLLKVSTGGVGGGTIFDPNPATLSYTSSPVIKDKKGNNTFDTNKIYDQFLNGDISNFYYNHDIPLSSTTAWAKLGFTDWTTFSTGFFKALDSLPNIDTPSGIIGGIAMSSLLTQWTDYTNLKRDLTNVIKDTNNFDLATRNQLITFNKYMLDFYQTYIAGPPLTVNPLFLTDDKKHVSLNEVDKTISNRHFLLDGKEKLFSYPKSYEDDSIIIVEKDSGHDLELKINDEVIDLEDLSNLELQNEDNWSNENIREINGHLVSWFISVIDNRIGVAILETGYSRAPYFIQEYMKDAIVNDKDYGLGFNLIPFNPITDTRGTMLNAYLNGEKLKINGIDEKNNLINFGSDNSKLFDNNTNEYIPIIINESISKKFGVSKNSLISMTINNDTIEVRENQNDEFKILRPGDVEVGAKKRTKHIYETSYRPNSAKSIQSTDGKNFADASVLSLSPVKIGGSNITSTTSSGSTNQTAVHKKFSEGNLIIGSEYLNKSFKVVGIQKSYGELQAWISNDQANKIKGYDKTQSQMFANWFAPESVKNNDYINWLSNGDDEYKKSIVKPILNEIIEIIEREEYKNTLTQYDVFKLKMNEAVGESYNVYQKIDKSFNNAFPVFNYKYSLDPEVKDLTRGLSTSQRFSDFSAQGMNGNYVLDPETGEPNFDKFVEGYGYSSFNTMVPLSEARQILSQITDVVNIIVIGLITLAILVATIIILLVTILVISENKEFLATMKLMGYSDHYVLRQILTPYIIGMLVVYILGFIGSWFFFIWGINMVAQNTSFVLPVSFEFWMPLMVFGILFLIYLSTMLVTYRQIKKIKPSLLLS
>NZ_CP048387.1|WP_162649379.1|177193_177886_+|hypothetical-protein
MLSRFTKKIEDIIVVVIAILFMFFAIDKISFISQQINYQSMILSFVVLVALNVALIKVIIFSLYKTKRIMKISNINKLHAYKKIILTLWLFVIFTTLISAKFFVLFIETNNKVWITSIIDKPSFKYLFFSSFIVSLGFVILFSIYFAFSIMLKLQINKKNAKDKNVMLSFSKWLNNYEVIEDVAKLIDTDNYLLFIKVFHISNDMEELVVTTMFSEKLKENKKSQTPPQV
>NZ_CP048387.1|WP_162649378.1|176719_177121_+|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-ATPase-subunit-type-1-TsaE
MIVKLEQLNKIAKDLMKELEGNTFVLLNGDLGAGKTTFTKQLIKELGVTENVTSPSFNILNQYKTSNYVINHMDAYRLKKTDEIDMFLETFEGAINIIEWPNNLGIDFSKYGKVIEINILVIDEYNRDFKIKK
>NZ_CP048387.1|WP_162649388.1|194577_195336_-|hypothetical-protein
MNPLFTALTASDWITLFSALATLMISIVSGIFVIKFNKWNRKREIESNLAKQEDKLEDMNRQFQNDIFSINSDISKESIHILDESFKAAIAKNKAIANFSKKAKENTEELQQSVYRSRLEISSQIEKHVYKFKNILRQKEMLITQYYKSKLISDEYKESNINVNNEIIYRCNVCNKVFDIQAEWNRYIKLSSSFTHELKDINNINKDFTKQLEEFVLESNVLEQLIGYGVVLSKNYKYYLKDEFIMFHDDCD
>NZ_CP048387.1|WP_162649390.1|195375_195909_-|acetyltransferase
MKENKVTKKSFFRNSGEKKVLRITSENDVKSYLFYTDISNILFILENGINPVNNIRDLITTEYTVWSYLEHDESIGLEFDNSNRKNFWGWIEESEADIKSIAVIGIDPSTLSDITVYDWSYDDKSKTVAINEPIGVEAIQWIMVKEKAEFNAIKARVSILNLKIRIFLGDNGSIIES
>NZ_CP048387.1|WP_162649391.1|195991_197419_+|proline--tRNA-ligase
MASNKMDKITSRDVDFSQWYTDVIKNSNLIDYGPVKGTTIYKPYGFAVWENIKGLFDLEFKKLGVDNVYFPLLIPESLMIKEKKHVEGFAPELWTVTQTGNTQLAEKLFIRPTSEVMIADHWAKEIRSHRDLPLKYNQWVNVMRAEKTTRPFLRGSEFLWQEGHTVHAYEAEAKKMTKDILDVYSKISREKLMIPVITGEKTENERFAGAEATYTIEAMMYDGQALQSGTSHYLGQNFTKGFDIKFQNKSQKEEHAYSTSWGVSTRIIGAIIMSHSDDFGLVLPSAIAPIQVGIIKIKDTDEVLKATSDIVSKLSKTLRVNIDESDKSFGFKISEAEIKGIPIRIEVGPRDLENGSVTISRRDIRNKVSVKLADVEKYVTEQINEYDKNIFNVAKEHLEKRIYTADTFDEYQNIINTKSGFVLVPFCGEVSCEEDIKKKSSTNSRCIPDDVEQVESKCFNCGKSSKNKVYFARAY
>NZ_CP048387.1|WP_162649392.1|197429_198368_+|alpha/beta-hydrolase
MKELQIKSSDGNLLHIYLWDKVENLKGVLQIVHGSCEHLARYDEFANYLNDHGWIVIGNDHRGHGKTAALQNQPLGFFGEDRGWAKLVEDTFVVNKYISETYANLPIAMLGHSMGSFIARTYIILHSKTIKAVILSGTAWYSNIQIKMARRMAKKHQKKFGATHIDDFIYNLSYKPLNKKYKKSTTGADWLSVDQDNVAKFVADPLCGFTFTSSGFKDLFSGLIYNQTMSKIENMDKNLPIMLVAGKEDPVGSYGKTVTKTYKKFNNQGLNVDMKLYPGVRHEILFDITKDKVMEDAMAFINQAIEKPKSNT
>NZ_CP048387.1|WP_162649394.1|198443_198962_+|DUF402-domain-containing-protein
MKLNTKILVHAYKHNGLLYRSWAKPKVFQETDEYIILSNNNILITEKNGKKWVTKDPALWILFKDKWYNIICMFKDNGVNYYCNIASPYINEEGTIKYIDYDLDIRVYEDMSYRILDLKEFNDHRIKWEYGPEIVKIVWETIDELKEMIKNKEGFFDQKLVAELYAESAQKK
>NZ_CP048387.1|WP_162649396.1|199073_200879_+|elongation-factor-4
MEKSRIRNFSIIAHIDHGKSTLADRILELTGAVDKREMQQQLLDTMDIERERGITIKLNSIQLRYTSKSDGQEYVFHLIDTPGHVDFTYEVSRSLAACEGALLVVDASQGIEAQTLANVYLAIENNLEIIPIINKVDLPAADPERVKKEIEDVIGIDCSDAPMISAKTGLNVEDVLEAIVKKIPAPRDAKDEEPLKALVFDSYYDKYRGVMVSVRLFAGRVKVGDKVRFVQSKAEYEVVELGVKTPYEVKKDFLEAGEVGWIAASIKTVRDVHVGDTVTLVENPTLEPLQGYKKLNPMVYCGVYPIDTARYKDLKEALEKISLSDAAIVYEPETSQSLGSGFRCGFLGMLHMDVIQERLEREYNLDLIATAPSVIYKITKTNGVVLELDNPAQLPDPSTIKTIEEPFVKATIMTPEASVGDLMQLCQEKRGIYIDMEVIDDTRRTLIYEMPLNEIVFDFFNRLKSISKGYASFDYDFIGNRISKLVKMDILLNGDLVDALSTIVHRDFAQGRGSILVKKLKEILPRQNFEIPIQAAIGSKIIARETIKAMRKDVTGYLYGGDVSRKKKLLEKQKKGKKRMKQIGSVEVPQEAFIAVLRVDD
>NZ_CP048387.1|WP_162649397.1|200924_201257_+|PTS-lactose/cellobiose-transporter-subunit-IIA
MSKINFEEVSFQIIAFSGDAKGAAMSAIYLAKEGKFKEAEEKLSEADGHMNTASHTHMDIVSAEASGEKFQIPVLFMHAEDQLLSTQTIMLLAKEFVEVYKKIGNKITKK
>NZ_CP048387.1|WP_162649398.1|201314_201938_+|hypothetical-protein
MAREEYKSTITDVKLIEEFNAEFESLSKQFDKRIYGSVTEERSRASKLIINQKLKKPVEEVFSQFLIDAAYSIHTSLKAEDLYEGGFYRTSGKSNKLITKVSKLELNKEISIIWYANNQQFIRSIKFYSNKKNTVTNIKFFNLATGMTSVAGYLERHLRTVYAKRQKVSFEVQIMRTQMALGIIPKEKHEATNKKIVRYLKYAENLY
>NZ_CP048387.1|WP_162649399.1|202239_202551_+|PTS-sugar-transporter-subunit-IIB
MKKLRILLVCSAGMSTSMLVKKMQDYCRKNGLDYEIQAMSSAMGKPQLDQWDICLIGPQVSYIANEFKSVTKIPVEIIPSQIYALGKGDKAIEFTHKLLGITV
>NZ_CP048387.1|WP_162649400.1|202587_204771_+|PTS-sugar-transporter-subunit-IIC
MSDKMNTNNLRQENPESFKQKSKRVMNEKVIPFMGKLGNQRHMGAIRDAFGTMIPLIIAGSISVLINAIIFGGAGSGYVSLLGMIAWAFNPDLDKEGVTALLADATTGWGQTSTIMGLAIGHINTITVGMMSIYTAFLLGYFIAISRNHSNPIVAGLTSMAGFGLSTMGEIAFFMDAKGLIAAIIFGLLCSEIFIKLTSVRALNIKLPDGVPPAVGKSFAVFLPVAITLLCVAGINIIVFAPAVVTGNLYVQGGSSWTISLSGDDGLKELNSLILGIEKEAWVGNELVSSFLEIEFTSFDQFTGYVDSLSVSEQSVIGSVLMTSSNGGSLALGNAKGQLVGFDQFTKLTAIFKDEQFILSINYQAVNLGSSSFGMAAAIFQFISSWFLGLVTGDSGIWVAILFVMVVSFFWFFGIHGTNVIAGVFDPIFLMVFGINSALVTSLNSYDAAYATGEMGIFARAFFDGFAFIGGAGATLPLLLMTLMFSKRQELKELAKYSTPPGVFNISEPVIFGYPLILNPVYLFPFMFAPVVNVVIAYIFMNIGAVKVPYLTAPWTAPFFLSSVLITLDIKALIPIFIIFAVDILLYLPFILLDNLLYFKKIRVTDPELYKAEMLYYVDPNHKFAVDTQHKYDALINKGDTIVDNVEVNTVFWAKRMKPEELEKRVEEEKTKALAKQKHYVEKAEALRTKRDSIAVEKHDAWAIKAKKRKAKNKMFANDFGDKAKNL

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Crispr_ID: NZ_CP048387_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP048387_2

216453-217006

Orphan

Consensus_repeat	Method
CATATTTGTTACATTTGATGTATTTCAA	CRISPRCasFinder
CATATTTGTTACATTTGATGTAT	CRT
ATTGAGATACATCAAATGTAACAAATATG	PILER-CR

7 spacers

The CRISPR arrays of NZ_CP048387_2

>merge|NZ_CP048387|2|216453-217006|CRISPRCasFinder,CRT,PILER-CR
CATATCAATCACATTTGATGTATTTCAGTTAGATATATCTTTGTTGAAGTTAGGTGTATTTAAAAACATGCTACCCATATTTGTTACATTTGATGTATTTCAATTTGCTATTAATCCATTGAAATTTATTGCTCCAAAAAACATACCATACATATTTGTTACATTTGATGTATTTCAACTGTCCAGGCTTTGATTGAAAGTCTCGGCTCTAGAAAACATACTACTCATATTTATTACATTTGATGTGTCTCAATCATCGATTTTTTGGTTAAAATTAGATGCTGCAAAAAACATTTGAGACATGTCTGTTACATTTGATGTATTTCAGTTATTTAGACTTTGGTTGAAAACTTTAGCATTAGAAAACATGCTGGCCATATTTGTTACATTTGATGTATCTCATTTAGATATGTTATTATTGAAGCTAAATGATGAGTTAAACATTTCTGCCATATTTGTTACATTTGATGTATTTCAATCACCAATGTCTTGATTAAAGTTTACTGTTGAATTAAACATGTGAGACATATTTGTTATATTTGATGTGTCTCAAT

>NZ_CP048387|2|1|216453-217005|CRISPRCasFinder
CATATCAATCACATTTGATGTATTTCAG	TTAGATATATCTTTGTTGAAGTTAGGTGTATTTAAAAACATGCTACC
CATATTTGTTACATTTGATGTATTTCAA	TTTGCTATTAATCCATTGAAATTTATTGCTCCAAAAAACATACCATA
CATATTTGTTACATTTGATGTATTTCAA	CTGTCCAGGCTTTGATTGAAAGTCTCGGCTCTAGAAAACATACTACT
CATATTTATTACATTTGATGTGTCTCAA	TCATCGATTTTTTGGTTAAAATTAGATGCTGCAAAAAACATTTGAGA
CATGTCTGTTACATTTGATGTATTTCAG	TTATTTAGACTTTGGTTGAAAACTTTAGCATTAGAAAACATGCTGGC
CATATTTGTTACATTTGATGTATCTCAT	TTAGATATGTTATTATTGAAGCTAAATGATGAGTTAAACATTTCTGC
CATATTTGTTACATTTGATGTATTTCAA	TCACCAATGTCTTGATTAAAGTTTACTGTTGAATTAAACATGTGAGA
CATATTTGTTATATTTGATGTGTCTCAA

>NZ_CP048387|2|1|216453-217000|CRT
CATATCAATCACATTTGATGTAT	TTCAGTTAGATATATCTTTGTTGAAGTTAGGTGTATTTAAAAACATGCTACC
CATATTTGTTACATTTGATGTAT	TTCAATTTGCTATTAATCCATTGAAATTTATTGCTCCAAAAAACATACCATA
CATATTTGTTACATTTGATGTAT	TTCAACTGTCCAGGCTTTGATTGAAAGTCTCGGCTCTAGAAAACATACTACT
CATATTTATTACATTTGATGTGT	CTCAATCATCGATTTTTTGGTTAAAATTAGATGCTGCAAAAAACATTTGAGA
CATGTCTGTTACATTTGATGTAT	TTCAGTTATTTAGACTTTGGTTGAAAACTTTAGCATTAGAAAACATGCTGGC
CATATTTGTTACATTTGATGTAT	CTCATTTAGATATGTTATTATTGAAGCTAAATGATGAGTTAAACATTTCTGC
CATATTTGTTACATTTGATGTAT	TTCAATCACCAATGTCTTGATTAAAGTTTACTGTTGAATTAAACATGTGAGA
CATATTTGTTATATTTGATGTGT

>NZ_CP048387|2|2|216753-217006|PILER-CR
CATGTCTGTTACATTTGATGTATTTCAGT	TATTTAGACTTTGGTTGAAAACTTTAGCATTAGAAAACATGCTGGC
CATATTTGTTACATTTGATGTATCTCATT	TAGATATGTTATTATTGAAGCTAAATGATGAGTTAAACATTTCTGC
CATATTTGTTACATTTGATGTATTTCAAT	CACCAATGTCTTGATTAAAGTTTACTGTTGAATTAAACATGTGAGA
CATATTTGTTATATTTGATGTGTCTCAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP048387.1\|WP_162649421.1\|220443_221301_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381297
NZ_CP048387.1\|WP_162649410.1\|210684_211353_+\|M48-family-metallopeptidase	unknown	unknown	gnl\|CDD\|307807
NZ_CP048387.1\|WP_162649423.1\|221405_222641_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223092
NZ_CP048387.1\|WP_162649425.1\|222783_225480_+\|DEAD/DEAH-box-helicase-family-protein	unknown	unknown	gnl\|CDD\|223989
NZ_CP048387.1\|WP_162649428.1\|226365_227178_-\|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl\|CDD\|376667
NZ_CP048387.1\|WP_162649404.1\|206275_207757_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048387.1\|WP_162649430.1\|227376_228279_-\|N-acetylmuramic-acid-6-phosphate-etherase	unknown	unknown	gnl\|CDD\|235467
NZ_CP048387.1\|WP_162650034.1\|228296_229997_-\|PTS-transporter-subunit-EIIC	unknown	unknown	gnl\|CDD\|181971
NZ_CP048387.1\|WP_162649416.1\|215081_215933_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048387.1\|WP_162649432.1\|230091_230868_-\|MurR/RpiR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224651
NZ_CP048387.1\|WP_162649407.1\|208589_209684_+\|DUF871-domain-containing-protein	unknown	unknown	gnl\|CDD\|377567
NZ_CP048387.1\|WP_162649427.1\|225575_226304_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048387.1\|WP_162649408.1\|209794_210184_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378077
NZ_CP048387.1\|WP_162649409.1\|210418_210613_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048387.1\|WP_162649414.1\|213148_214969_+\|translational-GTPase-TypA	unknown	unknown	gnl\|CDD\|224138
NZ_CP048387.1\|WP_162649412.1\|212288_213101_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048387.1\|WP_162649411.1\|211360_212275_+\|DnaJ-domain-containing-protein	unknown	unknown	gnl\|CDD\|274090
NZ_CP048387.1\|WP_162649418.1\|217614_218811_+\|phosphoglycerate-kinase	unknown	unknown	gnl\|CDD\|234613
NZ_CP048387.1\|WP_162649405.1\|207769_208519_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP048387.1\|WP_162649420.1\|218963_219794_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187632

Protein	Function_ID	Function_description	E-value
NZ_CP048387.1\|WP_162649421.1\|220443_221301_+\|aldo/keto-reductase	gnl\|CDD\|381297	cd19071, AKR_AKR1-5-like, AKR1/2/3/4/5 family of aldo-keto reductase (AKR) and similar proteins. Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. The family includes AKR1A/B/C/D/E/G/I, AKR2A/B/C/D/E, AKR3A/B/C/D/E/G, AKR4A/B/C, AKR5A/B/C/D/E/F/G/H, and similar proteins.	1.27341e-91
NZ_CP048387.1\|WP_162649410.1\|210684_211353_+\|M48-family-metallopeptidase	gnl\|CDD\|307807	pfam01863, DUF45, Protein of unknown function DUF45. This protein has no known function. Members are found in some archaebacteria, as well as Helicobacter pylori. The proteins are 190-240 amino acids long, with the C-terminus being the most conserved region, containing three conserved histidines. This motif is similar to that found in Zinc proteases, suggesting that this family may also be proteases.	1.64534e-33
NZ_CP048387.1\|WP_162649423.1\|221405_222641_+\|hypothetical-protein	gnl\|CDD\|223092	COG0013, AlaS, Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis].	6.11297e-36
NZ_CP048387.1\|WP_162649432.1\|230091_230868_-\|MurR/RpiR-family-transcriptional-regulator	gnl\|CDD\|224651	COG1737, RpiR, Transcriptional regulators [Transcription].	1.18048e-41
NZ_CP048387.1\|WP_162649430.1\|227376_228279_-\|N-acetylmuramic-acid-6-phosphate-etherase	gnl\|CDD\|235467	PRK05441, murQ, N-acetylmuramic acid-6-phosphate etherase; Reviewed.	5.31363e-143
NZ_CP048387.1\|WP_162650034.1\|228296_229997_-\|PTS-transporter-subunit-EIIC	gnl\|CDD\|181971	PRK09586, murP, PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed.	1.27586e-122
NZ_CP048387.1\|WP_162649428.1\|226365_227178_-\|sulfite-exporter-TauE/SafE-family-protein	gnl\|CDD\|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	1.45658e-12
NZ_CP048387.1\|WP_162649411.1\|211360_212275_+\|DnaJ-domain-containing-protein	gnl\|CDD\|274090	TIGR02349, Chaperone_protein_DnaJ, chaperone protein DnaJ. This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.	4.26798e-10
NZ_CP048387.1\|WP_162649408.1\|209794_210184_+\|hypothetical-protein	gnl\|CDD\|378077	pfam08877, MepB, MepB protein. MepB is a functionally uncharacterized protein in the mepRAB gene cluster of Staphylococcus aureus.	7.45428e-33
NZ_CP048387.1\|WP_162649425.1\|222783_225480_+\|DEAD/DEAH-box-helicase-family-protein	gnl\|CDD\|223989	COG1061, SSL2, DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair].	7.45373e-65
NZ_CP048387.1\|WP_162649414.1\|213148_214969_+\|translational-GTPase-TypA	gnl\|CDD\|224138	COG1217, TypA, Predicted membrane GTPase involved in stress response [Signal transduction mechanisms].	0
NZ_CP048387.1\|WP_162649407.1\|208589_209684_+\|DUF871-domain-containing-protein	gnl\|CDD\|377567	pfam05913, DUF871, Bacterial protein of unknown function (DUF871). This family consists of several conserved hypothetical proteins from bacteria and archaea. The function of this family is unknown.	8.01815e-137
NZ_CP048387.1\|WP_162649418.1\|217614_218811_+\|phosphoglycerate-kinase	gnl\|CDD\|234613	PRK00073, pgk, phosphoglycerate kinase; Provisional.	0
NZ_CP048387.1\|WP_162649405.1\|207769_208519_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	3.31266e-54
NZ_CP048387.1\|WP_162649420.1\|218963_219794_+\|SDR-family-oxidoreductase	gnl\|CDD\|187632	cd05374, 17beta-HSD-like_SDR_c, 17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs. 17beta-hydroxysteroid dehydrogenases are a group of isozymes that catalyze activation and inactivation of estrogen and androgens. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	5.23119e-92

>NZ_CP048387.1|WP_162649416.1|215081_215933_+|hypothetical-protein
METTNQNKWIILKDWKFWFQLSIAILILVALLTDYMDGMINIATKFTDPDSGLNMWQISNGNLNGYDYAGFTIFYFTFFTSQSNIFVILWCLISVIKWNKKSITDNDLLTYAIATYITITMLIFQTMLFPLSFIKNSEGEMAISSWRFINWFTQESLHLIGPLMFIIFVLIVRQKSSTIDTKTLVTKKIWVSFTYPLIWGIGELIRGEFYYQSNRPVGTQYHYFFMNIHLNGGESGYPIPGLSIPGILWFIIAILFILAIALGFFVLYNFIVNKRTQKQNVIA
>NZ_CP048387.1|WP_162649414.1|213148_214969_+|translational-GTPase-TypA
MKKIINIAVIAHVDAGKSTLVDAFLKQSGVFRDNQAVVDQVMDSNDQERERGITIYSKNCAIEYKDYKINIVDTPGHADFSSEVERIMKTVDTVILLVDSSEGPMPQTRFVLSKALDLGLKPILLINKIDKPDQRAMEVVDEVLELFMELDANDEQLEFTTMFGIAKRGIVQSSMEEESKDLSPLFEQIINEVGAYPESKSKEDTALQVSSLGYDSFIGRLGIGRLFQGSLKEGQTVSIAKNDGTTTRGKINKLFVYQGMARVAVTEAQAGEIVVVSGIDELTIGDVICASDKLVKMAPILVEEPTMSMNFLVNTSPFAGKVGKLLTTRNIKERLDKELEVNVGLRVDALSESSADGFKVFGRGELHLSVLIETMRREGFELGISRPEVVFHKDEKGNKTEPVERVILDVPTEYQGTVINNLNLRKGIMIDMDSNGIRDKITFEVPTRGLIGFKSEFVNETRGEGIMVKSFKAYEEYKGKIPARKNGVMISMADGVTLPYALSNLEERGTLFLGPQVQVYEGMIVGLHSRANDLNVNPTTGKKLTNTRSSGTDESTKLTPARKFTLEEALEFIEWDEWVEVTPVDVRLRKRWLKENDRKQHRYDMK
>NZ_CP048387.1|WP_162649412.1|212288_213101_+|hypothetical-protein
MDLTYVRNRDFWEKRSINIIKTELLFLHATAEYRHSWIINFTYDAVNFWNESDSIEQFENKLTISFNNYVLKNVDNFERITELEDTYSKIKSTTSVFRMFLDELENYFNKISSEKEELVFDILASHLVTLHEQTKAYFGAVSLNQAVDSESFRMLTSFYNKVVPQTDVIAGELVDLMYDILNWTVSLYGELLDLQAMTKKQDYHAEVILNFARETGTGIYFFLYFAESILDEFDIGEERIDELLEYENEKWNEIRGSENIDNIKTHLLNN
>NZ_CP048387.1|WP_162649411.1|211360_212275_+|DnaJ-domain-containing-protein
MAFWSKSKTQNYSKTNIDEYFIEWTKNESERVIYDTSIVKVINDSYEKSLNALLSKQRSAFINKSFSKEIKIMGINESFITVPGATHFLNIQAELYSTYDALLAQLTLVALKKYGYLCIKKFYEIVDDKFERFDTSERMIQRYIGIATTEIINGYENIIKKSTIYINQAIDENLILEFLDLGLNDSFYFSRVLKESTELTLSMVDYKNEYGQDNTFIQTIGLESTFENIDDFVEKTQTVYMDNSVENALKMFGLTSTSDSNELKQAYRKLAKQYHPDLNKDADANIVMQNINIHKAILDEYFGE
>NZ_CP048387.1|WP_162649410.1|210684_211353_+|M48-family-metallopeptidase
MKLKKQLSYGGKLIEYFLEIKDQKSIRLRIDNQKIIVSAPVYSQDWQIEQLIYKNIKKILMMVENQKTRYPFIIEGNILKIKIFGEYKDFEIINTNITASIKNKNVVKMYDNQDEFISNTYKRLSILYYDFFKDKLLYWSKKNELDIKNLSVKLMKSRWGVCYPELDKIILNTTLIHYPIECMDYVINHELAHTIHKNHSKDFWYLVEKNYQNYKEVSKLLK
>NZ_CP048387.1|WP_162649409.1|210418_210613_-|hypothetical-protein
MIQVLIILGAISFCAPFIIWMVVRFLDKQRQRPMYYKKQIIGFSFLVCFLLMILFLGLSIALSL
>NZ_CP048387.1|WP_162649408.1|209794_210184_+|hypothetical-protein
MNYKILDNDFNLKYDGKIVEYNTKYYRYRKARKTNKKEGYFVAFWEKENKINVPFNSKMDYDGFIIYIKDKKLEGFFVFSKDFLVENGYLKSEKFNGKMGFRVYPIQTDTMNETAIKTYNTTKSFFKII
>NZ_CP048387.1|WP_162649407.1|208589_209684_+|DUF871-domain-containing-protein
MEKKKIGISIYPDKAKLQDTKDYLDLAKKYNYEIVFVSFIHLKKDAKEELNTVIEAIKYAKSLGFYILADVHFPSLEMLGVPINDFRKLKDMGVDSVRFDSPAMASDLAALTHNDYELDIQLNMSNNDSLIDNVLDFKPVLTRLQGGHNFYPQKNTAISWDFFVEATKRYTSKNLSTLAFIGSHNGNQGPAAVNKELPTLEFCRDLPVESQAKVLFYSNTINNVLFGNAFASEEELKKVSELDREEITFTLDWEKSITKEEKEIANYKEHFRRGDITEFFIRSTMSRVIWASSDIKPRDKKSTYKRGDVVIVNNNGASYKGELHIILKDGYVDENNQYNQIGKVRTGELFLMNFVEPWSRFRLN
>NZ_CP048387.1|WP_162649405.1|207769_208519_+|ABC-transporter-ATP-binding-protein
MEFKFKNFTKLFKNGKGIENINIDVKSGEILGLIGDNGSGKSTFIKSIFGEYTRQTGEIIIDNKIIDKSDLGTFSLFPDQSIYPQNISIFEFIKYTLKLSGANKKTIKKSVIEALENVNLIDYKNKTFKELSAGMQKRALLANALITNPIILFLDEPTANLDVKTRIQFLEILSDLAKVGIAIVITSHLIDELANLVDKLAILDNGKLTYCDYTNNDEESIKDLYIKYSENITGSINVSKFVKNKFEND
>NZ_CP048387.1|WP_162649404.1|206275_207757_+|hypothetical-protein
MFVIIANIVGIGFIFIFNLYSFIKMYLEDETNGIHGLEKRMGVSNLQIYIMRLFSNKTFIFFWIVISFVLFLMINSIFSEQYSSYILENLTIGLFTQVIFDFMITALISLTLLVKSVKLTSILVSSISILFMLFPITGSVQFIMTPPSASEIWTNNPPEVYKKLTKNENYFISKLVKEYKSNEVMFIVNENDGSLKSNIYTRDIYKGGLILNYPDVFEKINNEGKYQYELHFENYENSLTYKFFNSFQEKIGVENYGSIDSNFLIGQRKSDWSGKGQLKDVIDILKNNKNNFKDIISPDEVENLAEAISYTYNFYPSVYSKFGATNLMSGVFRNIDSESINQYRTGSAGIQLFAAVLNILMSEVFHENEYSYNDMLEINNLYNESQKNQLKIQYFSNPFTHLLLTSILSNYKADYYTNRFNTTLSPLPISNNTIGAKPIFEKIENEKEIKYKIVNLEFQKNKINVGLIYLWWILISSLVFTFSAYIFLKKMNI
>NZ_CP048387.1|WP_162649418.1|217614_218811_+|phosphoglycerate-kinase
MKKTLHDVKVEGKVVLVRVDFNVPIKDGVITEDNRIKSAIPTIKHLIEKGSRIVLFSHLSRIKEEADKAKKSLAPVAKRLGELLKKEVKFISQTRGAELETAIKSLKAGEIVVVENTRFEDVANGEVVKFESKNNAELGKYWASLGEVFVNDAFGTAHRAHASNVGIASNISDSCVGFLVEKELSALAAGIDKPAKPFVAIIGGAKVSDKIGVIDNLLKKADKILIGGGMAYTFFKAQGHNIGKSLCEEDKVALAKEYLAKANGKIILPIDSANNTDFKDSKATFSGVDLPDDVMGLDIGPKSIELFKNELKGAKTVVWNGPMGVFEMENFKVGTVGVCEAIANLDGAFTLIGGGDSAAAAIQLGFADKFTHISTGGGASLEYMEGKVLPGIEAIKNK
>NZ_CP048387.1|WP_162649420.1|218963_219794_+|SDR-family-oxidoreductase
MKKQTWFITGASKGFGQILVNKLLEKGDRVVATSRNMNSFKDIDNDNFLGLEIKDLTNEKSIIEAFKQTINKFGTIDVLVNNAGYGIFGAFEEVTDKEIRDLFDVNVFGTFNTIRNVLPIMRKANKGRIINISSSYGFVGDKYWGAYNATKFAIDGLSEALSLELNQFNIKSTSIMPGPFRTNFLDNSSLSAVVKEGPYKKEITKMNELWAEWNGSQAGDPYKAMDALIKIVDENLDVDHIFFGQHAYNTAEQRIEKWKQEMKNFEHIGKDLDYSK
>NZ_CP048387.1|WP_162649421.1|220443_221301_+|aldo/keto-reductase
MSEAKSLKIKLHNGIMMPQVGFGTYRIQDQAIGVKAIAHAINSGYELLDTADIYRNHHIVREGIKQSNKNRNELFITTKLWPVSKDIKIYKDDFGVFLKQLDTDYIDLLIVHWPLPFGKVAYEAAEQLYKEGKVRAIGVSNYNKKQLEELISSVEIKPMVNQIELNPNAIRQDVVDFAKANDIAITSWQTMMEGKVSELEHFVKLSQKYKVDSPAIALKWAIQKGIAIIPKSVTPSRIETNLNDLALFKLTEEEIEMIDNLSTEKGMNVDSNNYISPTPATERVF
>NZ_CP048387.1|WP_162649423.1|221405_222641_+|hypothetical-protein
MIKNFLGYKLTTLQTTVNEFKNTSSYTLLKLNETIFFPTIAGQVCDLGFVVHNEQKYAILDLQLVDDEVIHKVELITDLVVGDSIVCELNIKHRNFVSANHTAAHLFYDTVIEDFPDSQGQGYFNNERTIRLDMSIKQKIDSKEVAKITKRVIDKIGKKAQKIELFTTKQIAQNEWGLSTDFNEKSLGDDVRIVRFGDISTQLCSGTHINNTSEIELFCIFSIEKKGNNIYRFYAATTKENLDKEVKLQQAEQHAELEILMNKYKTAKIKSSTVTKLLEECQLNLKEYKIILWKENLSKLKITVNDLLVEHDKKRRQQLINKYINVKFENKEDINYASINDDEISIKDAQQIADIILKNNPNSVIEFINLKDKTYLCKSNSIRSAIEIMQKKEFNVKGGGTPKVAQGKIIN
>NZ_CP048387.1|WP_162649425.1|222783_225480_+|DEAD/DEAH-box-helicase-family-protein
MFFTNQDTQQLLTEFKFAMREAHEINLIYPFISKSMLNKLTEEFDYCLSKNILINIITTTFDHQAKFNDLYELKKLQLNYPNIHIKVEDNLERHSQRIHIKAAIFKNYQETSVIIGSSNLTYKGIMTGREWNIKLTSETNFELVQQMSTEFERLWEEPLVDFKDDIEREKLLKQLQLNQINQYKNSSVDEFVQPRRFLFKFQKEIMQSLAYRRFQNKHKHLITMATGTGKTTVAAFDYKKLTEQNLKPVKLLFLAHQKEIIDQAINTYRQVLENRQFGDVLYDGKILSEKPTHLFATIQSLANKLTEFQPNDFDVIVFDEAHHLAANSFDKVYNYFKPQEILGLTATPEREDNQDIKKYFDNEIAYELRLWDAIQQKLLSPFDYFCIDDSQTNLLGTNLTSDREVFKKINTTSRNKLLFSTIEKYLGIYARPTCLIFCATVEHAKIVANYLQTKHLKATYLTSENTSDRKRILHEFQTGRINYLCVVNIFNEGIDIPEIDTIILLRPTNSKTVYLQQLGRGLRKTELKSRLEVYDLISNIDQKYDLTIGLRNLFAPNVQKLEHEKLELQLPYDSTIILEKNTHKLILKSLQRWYKSKTLLKLQVIEYYGLYKKDTLTKILEDNHLTLHEFYNSLDELMFNVAYSNSKFNSANNQTNRNKNIIKQFIFLNNYHIINYFYNRLTEKLKQKDINLDYDNLLVTCFLYEITSMERFLKIYPNYLDIPDLVDHFIGTHKMIVKELIMILRYKLEHENLIFSSTKDLLLIDCVYTVKQILAVVQRTNFLWYRDNLKILTFQAGFLTFDNSKQIILADEGGQEYGKMTKYDQANNKFYWSLPEKMTIKNKIIKDFNNLEITKYLFIHDQQNYELKHLFTKLYKHVGVGTFSQMLVDKYLTVEFDV
>NZ_CP048387.1|WP_162649427.1|225575_226304_+|hypothetical-protein
MFKDKIEAKKYYLSFILILWIIITILGTILMTNANEKLYIPGDIYPSDQAALHLNFFSINNLFKLNYVTGAAKINTDGVAIGGMITIISFSIFTIISSWFYVYYVKIDIKKSYLVLNVVPIAIVVMLSIFISRLNNMTTAIDINGMQSSVDFLIGDINDVLIVISNGKEYYYWTNSLVGNYVYTLGHASPAKIIINIIGCTNWVSFIFIAIRVDRENKKDKKRKMDENLIEIAKNMQDQNNQ
>NZ_CP048387.1|WP_162649428.1|226365_227178_-|sulfite-exporter-TauE/SafE-family-protein
MSLFILIPILFFGAILISSLGSISGVGGGVLFVPLLTMLLSNEGSDIKFISTVLVFVGSLFNVIFGLIRKEISFLVIGISLVFSIPFVLLGNYLSDLISETISQIIVIIFLIIVTILLILSEYVFKHKDNNIVVSSNWYTIRTKDSSINLFKLITIIILGSLITAITGMGGGPILMPLLLLWVGLSMKGSAPISHIIIACTSLVNIIINYSMFQNTEIMINYILPMTIGVIIGSVIVVFVKKYIKNEIIIKWILISLIWISVLKMIIDLF
>NZ_CP048387.1|WP_162649430.1|227376_228279_-|N-acetylmuramic-acid-6-phosphate-etherase
MNKINLKNIDTEKRNQNSKGLDLKTTVEVLKTINSEDKKIAIAIEKEINTIATIIDLIFEKSFKTNGRLFYVGAGSSGRIGVLDASEMLPTYGVGDKIFGLMAGGDKALRLPIEGAEDDKQLVIDDLKNYNFNKNDSVIAIGASGRTPYCISALEYAKSVGALPIGLSMTSNSEFRQYTDHIIEIVSGPEVVTGSTRMKSGTATKMVVNMISTTLMIKLGKVYDNLMVDLKATNEKLVSRTIGIVKEITNIKDEAKIKSTLEECNWDCKLAIVVLSKNITVEEAKKALESNDNVLRKVIN
>NZ_CP048387.1|WP_162650034.1|228296_229997_-|PTS-transporter-subunit-EIIC
MAKARDVALDIKNVIGEENIISYTNCMTRLRVKAKPNFEKENLKKVDGVLGLIVAGEEYQIVLGPGFVNKVALEFSKIVSIQSSETINENLDASQNKTAAEVAIETKNKLRGKSGVQTFLAKISKVFTPLIPAFIGAGLLTGIAGILSSTVNGDFTGHDTLKAWNGVLSIMLTLLTNVFIIAVGWRMAEEWGGNPGIGAMIAAVYTPFAGAAMAGLFIGGTDGVYNFLGITINNIEKNWLTVGFITWSTTTPSVASLGAPHAGLIGAMIAVGTTIFVEKQFRKIMPGALDTILTPVIVIFIMLMINLFLIIPVAGYMFTGITWLFNNLYTNPFGASILAGIFLFALVFGVHQGFLPIYFALIAETGVNGLFPILAMGGTSQVGVAIGLYIMAEKDSLLRKQISGAIIPGFLGIGEPLIYGVSLPRIKPFVVSCITAAFGGFYIGAISLWGGVQLGMNAPTGPGGLVATIMMTTVDGNVLVGVMVYLSAVILTYFLGAMFVMFAYSKIASNGSNKTKEIYKSDINIGKKIGWTIAFLTIVGIFVSWFVWWNKLTDTQKLELKGQKVE
>NZ_CP048387.1|WP_162649432.1|230091_230868_-|MurR/RpiR-family-transcriptional-regulator
MKKSAYQFLIENKENEILLQTIYNKLSKHESLDINEIAKESFISKSGITRFFTAHGFDGFKEFKYILLNEDQSFDTKISPKQIEEEIMIKPIQVTSSLNDDQIFLDLIKEIKKANTIYIHAIGGNNSVAYELQTRLERFGFKTSFSTDTHLMYVKLVNSTKDDLLIILSYSGETKETIKIAKAAKERNVTITSITRKSENTLSALSDIKLFTDSSDSVVKIMAFKSRTSMFYIVFKLTILIYSSDIEKYNSILKNNIY

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Crispr_ID: NZ_CP048387_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP048387_3

324948-325214

Orphan

Consensus_repeat	Method
AAATTTTAATCAAGATATTTCTTCTTGGGATGTATCAAATGTAACAAATATG	PILER-CR
TTTAATCAAGATATTTCTTCTTGGGATGTATCAAATGTAAC	CRT
TCAAGATATTTCTTCTTGGGATGTATCAAATGTAAC	CRISPRCasFinder

3 spacers

The CRISPR arrays of NZ_CP048387_3

>merge|NZ_CP048387|3|324948-325214|PILER-CR,CRT,CRISPRCasFinder
AAATTTCAGTCAAGATATTTCTTCTTGGGATGTATCAAATGTAACTAAAATGAATTATGTATTCTATAGGACTCAATTTAATCAAGATATTTCTTCTTGGGATGTATCAAATGTAACAGATATGTCGTCATTATTTGAAAATGTAAGAAGTTTTAATCAAGATATTTCTTCTTGGGATGTATCAAATGTAACCAATATGGAAGCTATGTTTTATTATGCAGAATCATTTGACCAAGATATTTCGAGTTGGGATGTATCAAATGTTAC

>NZ_CP048387|3|3|324948-325146|PILER-CR
AAATTTCAGTCAAGATATTTCTTCTTGGGATGTATCAAATGTAACTAAAATG	AATTATGTATTCTATAGGACTCAA
TTTAATCAAGATATTTCTTCTTGGGATGTATCAAATGTAACAGATATGTCGT	CATTATTTGAAAATGTAAGAAGT
TTTAATCAAGATATTTCTTCTTGGGATGTATCAAATGTAACCAATATG

>NZ_CP048387|3|2|324952-325214|CRT
TTCAGTCAAGATATTTCTTCTTGGGATGTATCAAATGTAAC	TAAAATGAATTATGTATTCTATAGGACTCAA
TTTAATCAAGATATTTCTTCTTGGGATGTATCAAATGTAAC	AGATATGTCGTCATTATTTGAAAATGTAAGAAGT
TTTAATCAAGATATTTCTTCTTGGGATGTATCAAATGTAAC	CAATATGGAAGCTATGTTTTATTATGCAGAATCA
TTTGACCAAGATATTTCGAGTTGGGATGTATCAAATGTTAC

>NZ_CP048387|3|2|324957-325214|CRISPRCasFinder
TCAAGATATTTCTTCTTGGGATGTATCAAATGTAAC	TAAAATGAATTATGTATTCTATAGGACTCAATTTAA
TCAAGATATTTCTTCTTGGGATGTATCAAATGTAAC	AGATATGTCGTCATTATTTGAAAATGTAAGAAGTTTTAA
TCAAGATATTTCTTCTTGGGATGTATCAAATGTAAC	CAATATGGAAGCTATGTTTTATTATGCAGAATCATTTGA
CCAAGATATTTCGAGTTGGGATGTATCAAATGTTAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP048387.1\|WP_162649525.1\|343225_343822_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048387.1\|WP_162650041.1\|331908_332718_+\|DUF285-domain-containing-protein	unknown	unknown	gnl\|CDD\|308794
NZ_CP048387.1\|WP_162649522.1\|338564_341036_+\|DUF285-domain-containing-protein	unknown	unknown	gnl\|CDD\|308794
NZ_CP048387.1\|WP_162649512.1\|313320_314889_+\|AAA-domain-containing-protein	unknown	unknown	gnl\|CDD\|184118
NZ_CP048387.1\|WP_162649513.1\|314907_316440_+\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|236815
NZ_CP048387.1\|WP_162649518.1\|324299_324731_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048387.1\|WP_162649529.1\|345808_346270_+\|CinA-family-protein	unknown	unknown	gnl\|CDD\|334938
NZ_CP048387.1\|WP_162650042.1\|344787_345201_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|273116
NZ_CP048387.1\|WP_162649506.1\|309061_309835_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048387.1\|WP_162649527.1\|344008_344761_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048387.1\|WP_162649514.1\|321911_322238_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048387.1\|WP_162649511.1\|312644_313307_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048387.1\|WP_162649516.1\|322307_322703_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048387.1\|WP_162649519.1\|332956_335497_+\|DUF285-domain-containing-protein	unknown	unknown	gnl\|CDD\|308794
NZ_CP048387.1\|WP_162649520.1\|335651_338264_+\|BspA-family-leucine-rich-repeat-surface-protein	unknown	unknown	gnl\|CDD\|308794
NZ_CP048387.1\|WP_162649523.1\|341569_343177_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224117
NZ_CP048387.1\|WP_162650039.1\|320163_320772_+\|DUF285-domain-containing-protein	unknown	unknown	gnl\|CDD\|308794
NZ_CP048387.1\|WP_162649507.1\|309863_310598_+\|DUF4293-domain-containing-protein	unknown	unknown	gnl\|CDD\|379484
NZ_CP048387.1\|WP_162649509.1\|310608_312561_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048387.1\|WP_162650040.1\|329379_329868_+\|DUF285-domain-containing-protein	unknown	unknown	gnl\|CDD\|308794

Protein	Function_ID	Function_description	E-value
NZ_CP048387.1\|WP_162650041.1\|331908_332718_+\|DUF285-domain-containing-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	3.9285e-61
NZ_CP048387.1\|WP_162649512.1\|313320_314889_+\|AAA-domain-containing-protein	gnl\|CDD\|184118	PRK13531, PRK13531, regulatory ATPase RavA; Provisional.	1.64034e-107
NZ_CP048387.1\|WP_162649513.1\|314907_316440_+\|VWA-domain-containing-protein	gnl\|CDD\|236815	PRK10997, yieM, ATPase RavA stimulator ViaA.	1.1259e-58
NZ_CP048387.1\|WP_162649507.1\|309863_310598_+\|DUF4293-domain-containing-protein	gnl\|CDD\|379484	pfam14126, DUF4293, Domain of unknown function (DUF4293). This family of integral membrane proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 136 and 154 amino acids in length.	0.00150185
NZ_CP048387.1\|WP_162649529.1\|345808_346270_+\|CinA-family-protein	gnl\|CDD\|334938	pfam02464, CinA, Competence-damaged protein. CinA is the first gene in the competence-inducible (cin) operon, and is thought to be specifically required at some stage in the process of transformation. This Pfam family consists of putative competence-damaged proteins from the cin operon. Some members of this family have nicotinamide mononucleotide (NMN) deamidase activity.	1.15594e-31
NZ_CP048387.1\|WP_162650042.1\|344787_345201_-\|hypothetical-protein	gnl\|CDD\|273116	TIGR00521, coaBC_dfp, phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase. This model represents a bifunctional enzyme that catalyzes the second and third steps (cysteine ligation, EC 6.3.2.5, and decarboxylation, EC 4.1.1.36) in the biosynthesis of coenzyme A (CoA) from pantothenate in bacteria. In early descriptions of this flavoprotein, a ts mutation in one region of the protein appeared to cause a defect in DNA metaobolism rather than an increased need for the pantothenate precursor beta-alanine. This protein was then called dfp, for DNA/pantothenate metabolism flavoprotein. The authors responsible for detecting phosphopantothenate--cysteine ligase activity suggest renaming this bifunctional protein coaBC for its role in CoA biosynthesis. This enzyme contains the FMN cofactor, but no FAD or pyruvoyl group. The amino-terminal region contains the phosphopantothenoylcysteine decarboxylase activity. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pantothenate and coenzyme A].	1.19507e-14
NZ_CP048387.1\|WP_162649522.1\|338564_341036_+\|DUF285-domain-containing-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	3.06406e-35
NZ_CP048387.1\|WP_162649519.1\|332956_335497_+\|DUF285-domain-containing-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	5.12313e-47
NZ_CP048387.1\|WP_162649520.1\|335651_338264_+\|BspA-family-leucine-rich-repeat-surface-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	6.09387e-51
NZ_CP048387.1\|WP_162650039.1\|320163_320772_+\|DUF285-domain-containing-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	1.55379e-54
NZ_CP048387.1\|WP_162649523.1\|341569_343177_+\|hypothetical-protein	gnl\|CDD\|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	3.62339e-12
NZ_CP048387.1\|WP_162650040.1\|329379_329868_+\|DUF285-domain-containing-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	1.38054e-48

>NZ_CP048387.1|WP_162649518.1|324299_324731_-|hypothetical-protein
MIIFEAAALSAEIVTVPSPAVTPAEIVITPATFVAVMDPAAVISTFVKSAKFVILIVELSPVYSSSESLSVWININAFTVILITFDIAALSAEIVIVPSPAVAPAKIVTTPATFVAVIAPVDVTSGFVKSAKFVILIVELFPT
>NZ_CP048387.1|WP_162649516.1|322307_322703_-|hypothetical-protein
MFPLLFTNSMFPSLIIFGLIKLFQLETIIVWVSPANNSKSFLSTSISILFEILTSIVFVSIAFEAETVKVPLPFFKPLISIFSPINSPLANSSPITFKFVNRLKLFTFISFSWSTYMSTFSKSNCIITFNT
>NZ_CP048387.1|WP_162649514.1|321911_322238_-|hypothetical-protein
MTSISKSSGIVFLDLITLIIVSGSGLTINPKSKFFIISLISFLTLKVMITSPAYETVFFEVTLILKPESEFLFFKNSIFKSKSLKISSEILFVDLIALKIVSVSLSAK
>NZ_CP048387.1|WP_162650039.1|320163_320772_+|DUF285-domain-containing-protein
MDSEWIDPKTGEVKLGTVIPKNVTKVTRIGYGENGLAHRMPNSVIEVPDLISPKITDASKLFWAATSFNGDISDWDVSNVINMDKMFYGANSFDQDISGWDVSNVTSMEMMFRGSDSFNQDISAWDVSNVTSMDYMFATAILFDQDISDWDVSNVTSMESMFYYANSFDQDISGWDVSNVTNYGTFATQCPIDKTSKMPKFK
>NZ_CP048387.1|WP_162649513.1|314907_316440_+|VWA-domain-containing-protein
MEFQFENKIDTKIKKELSYLHEKDLKNPVYMAAVKSRGLPAHFFDDQINNFHDKEIEKEIKNIKLSPQLEKEIYLFYWVKINGYEGTKKNYSKIQDFLFKVKSRFYNRLNFYRYEFNKVGSDQNMVYKNFIKTWEIILIKNVVEYRMIEIEEKRIKFIQKLYDYIEIYVASSKLLKTVWNFFGDVFEETLAKNLNMEILESFANYLQNNPAIMEIASLIGRQTSKSELIEERKMLDRPIKTKIRPVYYSTEEIVGVSQSNVLEHTLTTEFAVLGIPVLETLFYKKMLESQLQVFDFIALDEVPERIVEERVYNVEVPDKKGPIVLCIDTSASMQGSPEQIAKSLALAITKIAIKEKRNFYMINFSGGIEVLDFSKTKTMLSSLVDFLSQSFNGSTNIEPAITHAARVMNQKKWHNSDMLMISDFLNPDLSEDTLERVKHLKSIRNRFHAISIGILGNKNTQQLFNNSWTYDPRDPFTSEKIISDLSNELNSDLKHPTSPKEIFESVSNRK
>NZ_CP048387.1|WP_162649512.1|313320_314889_+|AAA-domain-containing-protein
MAGSNRIEELINELQKGVYEKNEVFVLSVLAMLSGESIFLLGKPGIAKSLVARRIKYAFKDGSIFEYLMNRFSTPEEIFGPISIEGIQKGEYKRLTKKYLPSADIVFLDEIWKAGPSIQNTLLTIINEKIFRNAGEDVKVPMKLLMSASNELPAPGQGLEALFDRFIIRYIVEGLKDENNFNEMIAGDAPLEISVDSKLQIKAEEFFAWQKEIKKVQMDELTFNFISDFRKGLDVATEGEAYISDRRWKKIAGLMKTSAYFNGRVKVDKQDWLIIPYCIWDDEQQEEEYSALFNEFYFESLKVDIFKKWEALKVELAELKKQYAFVLDNTTEKSIYQNVFSKKLPGSFHRLLWKNSENPINFMKAEDYTKIFHSNGKATEIEIFCGDELDNLISIKKVSVVYINEKTLQINGDTVGLEIQNKKDQSELDALQTKINEVAWKVDNLPNLMVEEKERLEKTSTIFFRQQFDLVLNNAFAEYIEIVNQQKIAEHDNLEKRVQVINETPVEETAELVSNKPGSNIE
>NZ_CP048387.1|WP_162649511.1|312644_313307_+|hypothetical-protein
MSIKPNHKSQFPELNLLDEENKRSKYETELSELTKLEQKKFSYIPPTKVNNFAGRRLYWSTKLEVAGRILILLAALMTIITSFILGKYGILVTVEKLIGQELVFFGISLSDAISYGFLFIALLFSLFYILPSFLAKTVGTVKKWSVVFIIFAIAHFVFFELMCATLIVINSIRINNNETINDIYPIIIIMVLVTTIIQIIGSCFLIVKSDDIKQRMNLEI
>NZ_CP048387.1|WP_162649509.1|310608_312561_+|hypothetical-protein
MAMKKFWKLTRFQNKLLFVILGISVVVAPTGAIIYSFTTSSSYSIKDPWADASDLNKSLDKYFNDKLSPTRTTFRVGETQGTGIYVKESDITDIRKELINGNEWMSKMSEADLNEMLSGTGVSISENNKLIFNDKEMKELALFPTILKYPYEGNNKLGEVFFSPSNKEAGIFKYNIRFCLRLGIVGFDNKKYDLKKKYDFTLRHDQETTLPVLLKLINNESIQKFIQVNESFNSNESVLKGLLKTYYNLANNSGMDFYSEIKPKSGSLPANNKYAQDYANASSIHIKYDSRKINNIKSFGSNLYNQHLGDYNTVEYIFNKIGISMPKIENDITGFRLRDRNSGSWTSMSSSDIKTYKGYINYGYSDGKEITDDVENSLFQSEHKIFTNKVNIKFLDVNKSTDIYYDQQPYSRGSINYNNYNIVNDVNDVVNNIKYEDSRDLINQKLSSKQNQIEQSIVNTIKKSLDSNGVSQSVFDEVRVSSPMVSNIATPGYATRKDNDKVYFDKTIDFNRVDSKAFFYSEGRSVNRITQYHFIPSKVINDPYGKAKYNLSSLNISNIPNNLWDTDTYESEIIYYVKNLMRQSIDSWPNKFKPGNEANEMSYKLNGPIKGGKLNEGSYTVTITAPNSLWNFKGSKTTNTFYVKKKSMLE
>NZ_CP048387.1|WP_162649507.1|309863_310598_+|DUF4293-domain-containing-protein
MIVRVEDKTNNLRVSWNTKIEVACRVLIITVTIAILLMSFFVGAGFAKIYDQFYNLIGEIAHEDLKGHYIKMGSIALIIFLPLSILISFPYIFMKNPNTIRIFILISLFIVISYVVSVFSIMLHFEKTYEFTNPYIKASYWVIGIGGLIILVSKVFLWREIKKQFKIKKTFEYLNEEKEFIKISKKQQDIVIKRDQLLKDGIELEDVEQHILDNANEISGNTIKKKHLSSVWEKKAKAKEADNK
>NZ_CP048387.1|WP_162649506.1|309061_309835_+|hypothetical-protein
MAKKKYRMRTPKEVQEPIINYVDPRSKSLQSLDEEPKDKIIHSLAISDLEKANGRFRSRTKKKSLTEVTDIYFSTGKDGFARLLITACQLTIIGSYMLLLISLSFLIPVVKDLFLELLPVNDEIFLLLFVPIAVLITTIFIVHIAFTIVIILLPILVAHKIKTLIKWSKISWYFSVFFGLATLLAVILIKQVLQSISWSYEHWNIELKLSKIQFNNYVITIGVALAISTLLGYPLLISSTKKQHNKNIKIQQYNLRR
>NZ_CP048387.1|WP_162650040.1|329379_329868_+|DUF285-domain-containing-protein
MPTSIIEVPDFISSKITSTKNLFRNAKTFDQDLSGWDVSNVTDMDLMFWNTKSFNGDISGWDVSNVTTMEKLFKSSRFNQDISGWDVSNVTNMSYMFDVNVSFNQDISGWDVSNVTNMDYMFYHAKTFDQDLSGWDVSNVTSFNSFAPECPIDGTSKMPKFK
>NZ_CP048387.1|WP_162650041.1|331908_332718_+|DUF285-domain-containing-protein
MNITNFADLTNLEVKAAGAVTATNVDGLITITAEATAGKGTITISADNAVASKVIKITVKENGWPKKMDSEWIDPTSGEIKSGAKIPEGVKKVTRIGYDGIGTAHRMPKSIIEVPDFISPKITNMGYMFESSKAFDQDISAWDVSNVTDMNRMFSGAKAFNQDISAWNVSNVTDMQNMFKGNQVFNQDISRWDVSSVTDMDQMFDEATKFNQNISRWDVSSVKKMYGMFRDAKAFNQNISAWNVSKVFSWRYFATYCPIDGTSKMPKFK
>NZ_CP048387.1|WP_162649519.1|332956_335497_+|DUF285-domain-containing-protein
MKADNNSKNKRIKITSIAAVILVILIFLSTFLSLYFFLWKNDRSTSTHLNTVITETELGWIDDNEDLKILSSVESLNSKANGVALKVKEKNETTASIFSTDLNYVGNVDVKFEQRQDINTLLSETPIIIGDEILGLEVEEIIEKIKDENPKLKELELLIEDFVPGEKIKFVVTTSTEGYTGKITFFITKISLSNIIVNKDLGLIKDKNEETIKNEIINKNKNNEAILKSLDESFIFEDTNYDGQKWTTKISVKNDDKFDPKPVEVSFLIPDKLDSIITKTDLGYLNDDKDDSILSEIKSINNISEGMFKDLDLQITRLTKNKDENPIEIIVYSKNPSYTGEVKVSFNIKKDISKIIKELDLGLISNPKPETIIEAIKSKNDIPEDLKIEISDVKDTTAMVTTTSEKYQGHVIVNYVLNILIELETEKEDIYIDEQKEINIINFNLLTDLKVIGDEFVSAKLTDGKILIKGLKNGKSSLTVTASNALEAKTIEVNVSNKIEIKVDKNELELLAGETQTIIVSNWEKLINPKAIKKEGNINIKNNNGSIVITADENAGNGNAQITISADNALNEQNISIIIKSKIEIMTDKDSDELYVGETSTINITNFSDLTNLEVIDDGQITTTNTEGVITIIAKEAAGEGNVTISADNAVASKIIRIIVKENSWPEKIDSEWIDQTSGEIKSGTKIPEGVKIVTRIGYDENGVVHRMPKTIMEVPEIISPKITSLYNMFAEASSFNNKNITNWDVSSVTNMEGMFWKTGVFNQDISAWDVSSVTNMRRMFYNTWAFNQDISAWDVSNVTNMEGMFQKSIVFNQDISRWDVSNVTVYTDFAGECKINGTYKMPKFK
>NZ_CP048387.1|WP_162649520.1|335651_338264_+|BspA-family-leucine-rich-repeat-surface-protein
MKADNNSKNKRVKITSIAAVILIILIMLSTFLSLYFFLWKNDKATTTHLNTVITETELGWIDDNEDLKILSSVESLNSKANGVALKVKEKNETTASIFSTDLNYVGNVDVKFEQRQDINTLLSESPIIIGDEILGLEVEEIIEKIKDENPKLKELELLIEDFVPGEKIKFVVTTSTEGYTGKITFFITKISLSNVIVNKDLGLIKDKNEETIKNEIINKNKNNEAILKSLDESFIFEDTNFDGQKWTTKISVKNDDKFDPKPVEVSFLIPDKLDSIITKTDLGYLNDDKDDSILSEIKSINNISEEMFKDLDLQITRLTKNKDENPIEIIVYSKNPSYTGEVKVSFNIKKDISKIIKELDLGLISNPKPETIIEAIKSKNDIPEDLKIEISDIKDTTAMVTTTSEKYQGHVIVNYVLNILIELETEKEDIYIDEQKEINIINFNLLTDLKVIGDEFVSAELIDGKILIKGLKNGKGSLTVTASNALEAKTIEVNVSNKIEIKVDKNELELLAGETQTIIVSNWGELLSPKVTKEGDINIENNSGIIAVTADKNTGNGNAQITISADNALNEQNILISIKSKIEIVTDKHSDEIYVGKTSTINITNFSDLTKPVVTAAGAVNATNVGGVITITAGATAGKGTITISADNAVESKVIAITVTENGWPEKMDSEWIDPTSEKIKSGTKIPVGVTKVTRIGYDEWGKAHEMPTSIIEVPDVVSPKIKDMSYLFYYSYAFNDVNIVNWNTSNVTKMSAMFSESKAFNQDISAWDVSNVTKMNSIFSFSIFNKDISNWDTSNVTSMYGVFWNNLEFNQDISAWDVSNVLSMDMMFENAKAFKQNISAWDVSNVKSYNRFSIGCPIDGTSKMPPKFK
>NZ_CP048387.1|WP_162649522.1|338564_341036_+|DUF285-domain-containing-protein
MKDDNNLEKKRNKKISLVAIILLFLIFLSTFLSLYFFLWKNDKPTTVHLNTVITETDLGWIDDNEDLTVLNSVETLNSKANGIALKVKQKNENSASIFSTDLNYVGDVDVNFDQRKDINTLLSNSPIIVGDNIKIWDEAVVIQEIKKENPELNELKLHIEDFVPGEKIKFVVTTSTEGYKGKITFFITKISLSSIIVNRDLGLIKDKNPETIIEQIINKNKNHEAILKSIDKDNLFQFSDVRFEEQKWTTSISIKSDPRFNEDEVVVSFLIPDKLESIITDTYLGYLVDDETETILSAIKSTNNISDEIFKDLDLQILKSTKSRSEAPMEISVYSRNTSYIGKVKITFNVKKDISEIITNSNLGLIANEESKTIANAVIKNNTMPDDLEIEIKDIKDTTAKVTTTSEKYQGDVDVNYVLNVVIQLDSEKVDIYVDQEKEINVTNFNLLTDLKVTGDEFVSVSDELIDGKILIKGQKDGKGSLTVTASNAMEAKTIEVNVSSKIKIEVDQTKLELLAGTTQTIKVSNWNNLLCPTVAKEGNIEIKSIDGTISITANENAGDENAQITINADNALNEQNISIAIKSKIEIITDKDSDVLDIGEKSTINITNYAHLTNTVVTADGTVTATNVDGVITITAGDLPGEGTITISADNAVKSKVIKITVKEISSLNQMDSEWIDPKTGEVKSGTAIPHGVTKITRIGYDEEGRAHRLPTTTVEVPNFISPKIIRLSDLFFNNPSFNQDISGWDVSNVISMNHLFSGAKSFNQNISNWKVSNVYNMDYMFRGAAAFNQDISNWDVSNVTSWTWFSLNCPINATSKMPKFK
>NZ_CP048387.1|WP_162649523.1|341569_343177_+|hypothetical-protein
MEKKYVLNNLLHMTFLMIILLLSLLSVTLFEVEGEKVIFYLFVSKDNFRPIEHSSSESMQLISVYSTVATILITPFGLVFSYIYFIKKNKNKQFYVFLIGFGIFHFITLLFNLICFYLMKGWISQSGQVMEINGKVVTSLNIKLTLSFVLIVCRSFSFIWIIIRNKMIAINKQKIREFELKTESLNSKRIPLGELASKIVEISDLRKKLGLEYLSEKNKLSEIVEINENLKIELDNASEISKDFNLKLSEISKNKNQLNYLEKQNEEVAVLIEEEKQKLSKAKATFESLNSSILSLEKDIKEKQKKSESMNAQYQKLLDLEKNENDLEKQNEKLVMSIEKQNEKLAMAKTTFESLNSSILSLEKDIKEKQEISESLDKKLVEETKHQSELEKQNEIVSVKIQEEKNKFFEANKDFEKITIDNKKLEQDIKKQEIHSNNMKNEVNENNKYRYQQRILLSNYRKLIASLKEQSEILIEAQARQEIELLKTKEEPNMSSERKIEVLEAALAFNEDQRKSQFEFQKMLFDEMDFNSKKE
>NZ_CP048387.1|WP_162649525.1|343225_343822_+|hypothetical-protein
METRLTKIQKFKMSLWIIGFIFFIVMSTLAVSFGIVLSRTKKIDLNSVITNTKLGFIDNNEPNTIINKVFELNPNAKDLSLKVDEFQIKDDYAIVYALNSNYSKNVKVSFELAIDLATLLEENPFLPVDKWNENNSDIDILKIIDEMYGEQLKDENGEKLPLEVIDKNINAKTVTIKTTKEGYFGKIVFYFLEKPSNN
>NZ_CP048387.1|WP_162649527.1|344008_344761_+|hypothetical-protein
MIFIAKLQIEINQLVDLNSKFPNVIQPDKIENILNSWETIKANPESHEHTSSLDIFKRELKGCIAMLENQGSPHQRMDEGADINNLQARLNRISSTVIKRQPLHPMEEEPVLPATQPTPLSEQADSYAKHTAFSEQAATYGQIHPMDVGEILPATQPTRVSAVGIEPSRPMIQPFLKTQITQQQPFQMNIKTQDQSNEKEKEISLATSLKQKYELELRTMIDKGNLDNELMKEKSMIIKSLELLIMNLKL
>NZ_CP048387.1|WP_162650042.1|344787_345201_-|hypothetical-protein
MDFGDLKVGVETEIHNRTSFHELHYPSHFNIADEADLTIVYPSTLLFMNRVALGIPDEYCSTLVSHTLKPVVFSPAGFSRMYNNAATKRNVEWIKSDNAPNWHILDPIIENLNVVEEDYYTVPDVKSTIEFIEKLIK
>NZ_CP048387.1|WP_162649529.1|345808_346270_+|CinA-family-protein
MERLIEWAINNNYSISTCESFTGGAFSNALTNVSGSSKAYKGGFVCYSNEFKVDVLKIDIKVIKKYSPVSVEVLTEMLNKTQKILLTDIVIGYTGWAPPLDKKNSDSGLTYYGFKIKDEITIIEYKLEANMDRSHFKTIMIEKLIKQIEKRMI

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Crispr_ID: NZ_CP048387_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP048387_4

337942-338191

Orphan

Consensus_repeat	Method
ATATTTCTGCTTGGGATGTATCAAATGT	CRISPRCasFinder

3 spacers

The CRISPR arrays of NZ_CP048387_4

>merge|NZ_CP048387|4|337942-338191|CRISPRCasFinder
ATATTTCTGCTTGGGATGTATCAAATGTAACTAAAATGAACTCTATTTTTTCATTCTCAATTTTCAATAAAGATATTTCAAATTGAGATACGTCAAATGTAACAAGTATGTATGGTGTGTTTTGAAATAACCTAGAATTTAATCAGGATATTTCTGCTTGGGATGTATCAAATGTATTAAGTATGGATATGATGTTTGAAAACGCAAAGGCATTCAAACAAAATATTTCTGCTTGGGATGTATCAAATGT

>NZ_CP048387|4|3|337942-338191|CRISPRCasFinder
ATATTTCTGCTTGGGATGTATCAAATGT	AACTAAAATGAACTCTATTTTTTCATTCTCAATTTTCAATAAAG
ATATTTCAAATTGAGATACGTCAAATGT	AACAAGTATGTATGGTGTGTTTTGAAATAACCTAGAATTTAATCAGG
ATATTTCTGCTTGGGATGTATCAAATGT	ATTAAGTATGGATATGATGTTTGAAAACGCAAAGGCATTCAAACAAA
ATATTTCTGCTTGGGATGTATCAAATGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP048387.1\|WP_162649525.1\|343225_343822_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048387.1\|WP_162650041.1\|331908_332718_+\|DUF285-domain-containing-protein	unknown	unknown	gnl\|CDD\|308794
NZ_CP048387.1\|WP_162649522.1\|338564_341036_+\|DUF285-domain-containing-protein	unknown	unknown	gnl\|CDD\|308794
NZ_CP048387.1\|WP_162649513.1\|314907_316440_+\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|236815
NZ_CP048387.1\|WP_162649518.1\|324299_324731_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048387.1\|WP_162649533.1\|348955_349918_+\|LD-carboxypeptidase	unknown	unknown	gnl\|CDD\|132883
NZ_CP048387.1\|WP_162649529.1\|345808_346270_+\|CinA-family-protein	unknown	unknown	gnl\|CDD\|334938
NZ_CP048387.1\|WP_162650042.1\|344787_345201_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|273116
NZ_CP048387.1\|WP_162649530.1\|346306_347338_+\|recombinase-RecA	unknown	unknown	gnl\|CDD\|236476
NZ_CP048387.1\|WP_162649527.1\|344008_344761_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048387.1\|WP_162649514.1\|321911_322238_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048387.1\|WP_162649511.1\|312644_313307_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048387.1\|WP_162649516.1\|322307_322703_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048387.1\|WP_162649519.1\|332956_335497_+\|DUF285-domain-containing-protein	unknown	unknown	gnl\|CDD\|308794
NZ_CP048387.1\|WP_162649535.1\|349991_351332_+\|signal-recognition-particle-protein	unknown	unknown	gnl\|CDD\|236780
NZ_CP048387.1\|WP_162650039.1\|320163_320772_+\|DUF285-domain-containing-protein	unknown	unknown	gnl\|CDD\|308794
NZ_CP048387.1\|WP_162650040.1\|329379_329868_+\|DUF285-domain-containing-protein	unknown	unknown	gnl\|CDD\|308794
NZ_CP048387.1\|WP_162649523.1\|341569_343177_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224117
NZ_CP048387.1\|WP_162649532.1\|347390_348935_+\|HDIG-domain-containing-protein	unknown	unknown	gnl\|CDD\|237177
NZ_CP048387.1\|WP_162649512.1\|313320_314889_+\|AAA-domain-containing-protein	unknown	unknown	gnl\|CDD\|184118

Protein	Function_ID	Function_description	E-value
NZ_CP048387.1\|WP_162650041.1\|331908_332718_+\|DUF285-domain-containing-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	3.9285e-61
NZ_CP048387.1\|WP_162649512.1\|313320_314889_+\|AAA-domain-containing-protein	gnl\|CDD\|184118	PRK13531, PRK13531, regulatory ATPase RavA; Provisional.	1.64034e-107
NZ_CP048387.1\|WP_162649513.1\|314907_316440_+\|VWA-domain-containing-protein	gnl\|CDD\|236815	PRK10997, yieM, ATPase RavA stimulator ViaA.	1.1259e-58
NZ_CP048387.1\|WP_162649533.1\|348955_349918_+\|LD-carboxypeptidase	gnl\|CDD\|132883	cd07062, Peptidase_S66_mccF_like, Microcin C7 self-immunity protein determines resistance to exogenous microcin C7. Microcin C7 self-immunity protein (mccF): MccF, a homolog of the LD-carboxypeptidase family, mediates resistance against exogenously added microcin C7 (MccC7), a ribosomally-encoded peptide antibiotic that contains a phosphoramidate linkage to adenosine monophosphate at its C-terminus. The plasmid-encoded mccF gene is transcribed in the opposite direction to the other five genes (mccA-E) and is required for the full expression of immunity but not for production. The catalytic triad residues (Ser, His, Glu) of LD-carboxypeptidase are also conserved in MccF, strongly suggesting that MccF shares the hydrolytic activity with LD-carboxypeptidases. Substrates of MccF have not been deduced, but could likely be microcin C7 precursors. The possible role of MccF is to defend producer cells against exogenous microcin from re-entering after having been exported. It is suggested that MccF is involved in microcin degradation or sequestration in the periplasm.	1.35347e-64
NZ_CP048387.1\|WP_162649535.1\|349991_351332_+\|signal-recognition-particle-protein	gnl\|CDD\|236780	PRK10867, PRK10867, signal recognition particle protein; Provisional.	0
NZ_CP048387.1\|WP_162650042.1\|344787_345201_-\|hypothetical-protein	gnl\|CDD\|273116	TIGR00521, coaBC_dfp, phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase. This model represents a bifunctional enzyme that catalyzes the second and third steps (cysteine ligation, EC 6.3.2.5, and decarboxylation, EC 4.1.1.36) in the biosynthesis of coenzyme A (CoA) from pantothenate in bacteria. In early descriptions of this flavoprotein, a ts mutation in one region of the protein appeared to cause a defect in DNA metaobolism rather than an increased need for the pantothenate precursor beta-alanine. This protein was then called dfp, for DNA/pantothenate metabolism flavoprotein. The authors responsible for detecting phosphopantothenate--cysteine ligase activity suggest renaming this bifunctional protein coaBC for its role in CoA biosynthesis. This enzyme contains the FMN cofactor, but no FAD or pyruvoyl group. The amino-terminal region contains the phosphopantothenoylcysteine decarboxylase activity. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pantothenate and coenzyme A].	1.19507e-14
NZ_CP048387.1\|WP_162649530.1\|346306_347338_+\|recombinase-RecA	gnl\|CDD\|236476	PRK09354, recA, recombinase A; Provisional.	0
NZ_CP048387.1\|WP_162649529.1\|345808_346270_+\|CinA-family-protein	gnl\|CDD\|334938	pfam02464, CinA, Competence-damaged protein. CinA is the first gene in the competence-inducible (cin) operon, and is thought to be specifically required at some stage in the process of transformation. This Pfam family consists of putative competence-damaged proteins from the cin operon. Some members of this family have nicotinamide mononucleotide (NMN) deamidase activity.	1.15594e-31
NZ_CP048387.1\|WP_162649519.1\|332956_335497_+\|DUF285-domain-containing-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	5.12313e-47
NZ_CP048387.1\|WP_162649522.1\|338564_341036_+\|DUF285-domain-containing-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	3.06406e-35
NZ_CP048387.1\|WP_162650039.1\|320163_320772_+\|DUF285-domain-containing-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	1.55379e-54
NZ_CP048387.1\|WP_162649523.1\|341569_343177_+\|hypothetical-protein	gnl\|CDD\|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	3.62339e-12
NZ_CP048387.1\|WP_162649532.1\|347390_348935_+\|HDIG-domain-containing-protein	gnl\|CDD\|237177	PRK12704, PRK12704, phosphodiesterase; Provisional.	3.41896e-132
NZ_CP048387.1\|WP_162650040.1\|329379_329868_+\|DUF285-domain-containing-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	1.38054e-48

>NZ_CP048387.1|WP_162649519.1|332956_335497_+|DUF285-domain-containing-protein
MKADNNSKNKRIKITSIAAVILVILIFLSTFLSLYFFLWKNDRSTSTHLNTVITETELGWIDDNEDLKILSSVESLNSKANGVALKVKEKNETTASIFSTDLNYVGNVDVKFEQRQDINTLLSETPIIIGDEILGLEVEEIIEKIKDENPKLKELELLIEDFVPGEKIKFVVTTSTEGYTGKITFFITKISLSNIIVNKDLGLIKDKNEETIKNEIINKNKNNEAILKSLDESFIFEDTNYDGQKWTTKISVKNDDKFDPKPVEVSFLIPDKLDSIITKTDLGYLNDDKDDSILSEIKSINNISEGMFKDLDLQITRLTKNKDENPIEIIVYSKNPSYTGEVKVSFNIKKDISKIIKELDLGLISNPKPETIIEAIKSKNDIPEDLKIEISDVKDTTAMVTTTSEKYQGHVIVNYVLNILIELETEKEDIYIDEQKEINIINFNLLTDLKVIGDEFVSAKLTDGKILIKGLKNGKSSLTVTASNALEAKTIEVNVSNKIEIKVDKNELELLAGETQTIIVSNWEKLINPKAIKKEGNINIKNNNGSIVITADENAGNGNAQITISADNALNEQNISIIIKSKIEIMTDKDSDELYVGETSTINITNFSDLTNLEVIDDGQITTTNTEGVITIIAKEAAGEGNVTISADNAVASKIIRIIVKENSWPEKIDSEWIDQTSGEIKSGTKIPEGVKIVTRIGYDENGVVHRMPKTIMEVPEIISPKITSLYNMFAEASSFNNKNITNWDVSSVTNMEGMFWKTGVFNQDISAWDVSSVTNMRRMFYNTWAFNQDISAWDVSNVTNMEGMFQKSIVFNQDISRWDVSNVTVYTDFAGECKINGTYKMPKFK
>NZ_CP048387.1|WP_162650041.1|331908_332718_+|DUF285-domain-containing-protein
MNITNFADLTNLEVKAAGAVTATNVDGLITITAEATAGKGTITISADNAVASKVIKITVKENGWPKKMDSEWIDPTSGEIKSGAKIPEGVKKVTRIGYDGIGTAHRMPKSIIEVPDFISPKITNMGYMFESSKAFDQDISAWDVSNVTDMNRMFSGAKAFNQDISAWNVSNVTDMQNMFKGNQVFNQDISRWDVSSVTDMDQMFDEATKFNQNISRWDVSSVKKMYGMFRDAKAFNQNISAWNVSKVFSWRYFATYCPIDGTSKMPKFK
>NZ_CP048387.1|WP_162650040.1|329379_329868_+|DUF285-domain-containing-protein
MPTSIIEVPDFISSKITSTKNLFRNAKTFDQDLSGWDVSNVTDMDLMFWNTKSFNGDISGWDVSNVTTMEKLFKSSRFNQDISGWDVSNVTNMSYMFDVNVSFNQDISGWDVSNVTNMDYMFYHAKTFDQDLSGWDVSNVTSFNSFAPECPIDGTSKMPKFK
>NZ_CP048387.1|WP_162649518.1|324299_324731_-|hypothetical-protein
MIIFEAAALSAEIVTVPSPAVTPAEIVITPATFVAVMDPAAVISTFVKSAKFVILIVELSPVYSSSESLSVWININAFTVILITFDIAALSAEIVIVPSPAVAPAKIVTTPATFVAVIAPVDVTSGFVKSAKFVILIVELFPT
>NZ_CP048387.1|WP_162649516.1|322307_322703_-|hypothetical-protein
MFPLLFTNSMFPSLIIFGLIKLFQLETIIVWVSPANNSKSFLSTSISILFEILTSIVFVSIAFEAETVKVPLPFFKPLISIFSPINSPLANSSPITFKFVNRLKLFTFISFSWSTYMSTFSKSNCIITFNT
>NZ_CP048387.1|WP_162649514.1|321911_322238_-|hypothetical-protein
MTSISKSSGIVFLDLITLIIVSGSGLTINPKSKFFIISLISFLTLKVMITSPAYETVFFEVTLILKPESEFLFFKNSIFKSKSLKISSEILFVDLIALKIVSVSLSAK
>NZ_CP048387.1|WP_162650039.1|320163_320772_+|DUF285-domain-containing-protein
MDSEWIDPKTGEVKLGTVIPKNVTKVTRIGYGENGLAHRMPNSVIEVPDLISPKITDASKLFWAATSFNGDISDWDVSNVINMDKMFYGANSFDQDISGWDVSNVTSMEMMFRGSDSFNQDISAWDVSNVTSMDYMFATAILFDQDISDWDVSNVTSMESMFYYANSFDQDISGWDVSNVTNYGTFATQCPIDKTSKMPKFK
>NZ_CP048387.1|WP_162649513.1|314907_316440_+|VWA-domain-containing-protein
MEFQFENKIDTKIKKELSYLHEKDLKNPVYMAAVKSRGLPAHFFDDQINNFHDKEIEKEIKNIKLSPQLEKEIYLFYWVKINGYEGTKKNYSKIQDFLFKVKSRFYNRLNFYRYEFNKVGSDQNMVYKNFIKTWEIILIKNVVEYRMIEIEEKRIKFIQKLYDYIEIYVASSKLLKTVWNFFGDVFEETLAKNLNMEILESFANYLQNNPAIMEIASLIGRQTSKSELIEERKMLDRPIKTKIRPVYYSTEEIVGVSQSNVLEHTLTTEFAVLGIPVLETLFYKKMLESQLQVFDFIALDEVPERIVEERVYNVEVPDKKGPIVLCIDTSASMQGSPEQIAKSLALAITKIAIKEKRNFYMINFSGGIEVLDFSKTKTMLSSLVDFLSQSFNGSTNIEPAITHAARVMNQKKWHNSDMLMISDFLNPDLSEDTLERVKHLKSIRNRFHAISIGILGNKNTQQLFNNSWTYDPRDPFTSEKIISDLSNELNSDLKHPTSPKEIFESVSNRK
>NZ_CP048387.1|WP_162649512.1|313320_314889_+|AAA-domain-containing-protein
MAGSNRIEELINELQKGVYEKNEVFVLSVLAMLSGESIFLLGKPGIAKSLVARRIKYAFKDGSIFEYLMNRFSTPEEIFGPISIEGIQKGEYKRLTKKYLPSADIVFLDEIWKAGPSIQNTLLTIINEKIFRNAGEDVKVPMKLLMSASNELPAPGQGLEALFDRFIIRYIVEGLKDENNFNEMIAGDAPLEISVDSKLQIKAEEFFAWQKEIKKVQMDELTFNFISDFRKGLDVATEGEAYISDRRWKKIAGLMKTSAYFNGRVKVDKQDWLIIPYCIWDDEQQEEEYSALFNEFYFESLKVDIFKKWEALKVELAELKKQYAFVLDNTTEKSIYQNVFSKKLPGSFHRLLWKNSENPINFMKAEDYTKIFHSNGKATEIEIFCGDELDNLISIKKVSVVYINEKTLQINGDTVGLEIQNKKDQSELDALQTKINEVAWKVDNLPNLMVEEKERLEKTSTIFFRQQFDLVLNNAFAEYIEIVNQQKIAEHDNLEKRVQVINETPVEETAELVSNKPGSNIE
>NZ_CP048387.1|WP_162649511.1|312644_313307_+|hypothetical-protein
MSIKPNHKSQFPELNLLDEENKRSKYETELSELTKLEQKKFSYIPPTKVNNFAGRRLYWSTKLEVAGRILILLAALMTIITSFILGKYGILVTVEKLIGQELVFFGISLSDAISYGFLFIALLFSLFYILPSFLAKTVGTVKKWSVVFIIFAIAHFVFFELMCATLIVINSIRINNNETINDIYPIIIIMVLVTTIIQIIGSCFLIVKSDDIKQRMNLEI
>NZ_CP048387.1|WP_162649522.1|338564_341036_+|DUF285-domain-containing-protein
MKDDNNLEKKRNKKISLVAIILLFLIFLSTFLSLYFFLWKNDKPTTVHLNTVITETDLGWIDDNEDLTVLNSVETLNSKANGIALKVKQKNENSASIFSTDLNYVGDVDVNFDQRKDINTLLSNSPIIVGDNIKIWDEAVVIQEIKKENPELNELKLHIEDFVPGEKIKFVVTTSTEGYKGKITFFITKISLSSIIVNRDLGLIKDKNPETIIEQIINKNKNHEAILKSIDKDNLFQFSDVRFEEQKWTTSISIKSDPRFNEDEVVVSFLIPDKLESIITDTYLGYLVDDETETILSAIKSTNNISDEIFKDLDLQILKSTKSRSEAPMEISVYSRNTSYIGKVKITFNVKKDISEIITNSNLGLIANEESKTIANAVIKNNTMPDDLEIEIKDIKDTTAKVTTTSEKYQGDVDVNYVLNVVIQLDSEKVDIYVDQEKEINVTNFNLLTDLKVTGDEFVSVSDELIDGKILIKGQKDGKGSLTVTASNAMEAKTIEVNVSSKIKIEVDQTKLELLAGTTQTIKVSNWNNLLCPTVAKEGNIEIKSIDGTISITANENAGDENAQITINADNALNEQNISIAIKSKIEIITDKDSDVLDIGEKSTINITNYAHLTNTVVTADGTVTATNVDGVITITAGDLPGEGTITISADNAVKSKVIKITVKEISSLNQMDSEWIDPKTGEVKSGTAIPHGVTKITRIGYDEEGRAHRLPTTTVEVPNFISPKIIRLSDLFFNNPSFNQDISGWDVSNVISMNHLFSGAKSFNQNISNWKVSNVYNMDYMFRGAAAFNQDISNWDVSNVTSWTWFSLNCPINATSKMPKFK
>NZ_CP048387.1|WP_162649523.1|341569_343177_+|hypothetical-protein
MEKKYVLNNLLHMTFLMIILLLSLLSVTLFEVEGEKVIFYLFVSKDNFRPIEHSSSESMQLISVYSTVATILITPFGLVFSYIYFIKKNKNKQFYVFLIGFGIFHFITLLFNLICFYLMKGWISQSGQVMEINGKVVTSLNIKLTLSFVLIVCRSFSFIWIIIRNKMIAINKQKIREFELKTESLNSKRIPLGELASKIVEISDLRKKLGLEYLSEKNKLSEIVEINENLKIELDNASEISKDFNLKLSEISKNKNQLNYLEKQNEEVAVLIEEEKQKLSKAKATFESLNSSILSLEKDIKEKQKKSESMNAQYQKLLDLEKNENDLEKQNEKLVMSIEKQNEKLAMAKTTFESLNSSILSLEKDIKEKQEISESLDKKLVEETKHQSELEKQNEIVSVKIQEEKNKFFEANKDFEKITIDNKKLEQDIKKQEIHSNNMKNEVNENNKYRYQQRILLSNYRKLIASLKEQSEILIEAQARQEIELLKTKEEPNMSSERKIEVLEAALAFNEDQRKSQFEFQKMLFDEMDFNSKKE
>NZ_CP048387.1|WP_162649525.1|343225_343822_+|hypothetical-protein
METRLTKIQKFKMSLWIIGFIFFIVMSTLAVSFGIVLSRTKKIDLNSVITNTKLGFIDNNEPNTIINKVFELNPNAKDLSLKVDEFQIKDDYAIVYALNSNYSKNVKVSFELAIDLATLLEENPFLPVDKWNENNSDIDILKIIDEMYGEQLKDENGEKLPLEVIDKNINAKTVTIKTTKEGYFGKIVFYFLEKPSNN
>NZ_CP048387.1|WP_162649527.1|344008_344761_+|hypothetical-protein
MIFIAKLQIEINQLVDLNSKFPNVIQPDKIENILNSWETIKANPESHEHTSSLDIFKRELKGCIAMLENQGSPHQRMDEGADINNLQARLNRISSTVIKRQPLHPMEEEPVLPATQPTPLSEQADSYAKHTAFSEQAATYGQIHPMDVGEILPATQPTRVSAVGIEPSRPMIQPFLKTQITQQQPFQMNIKTQDQSNEKEKEISLATSLKQKYELELRTMIDKGNLDNELMKEKSMIIKSLELLIMNLKL
>NZ_CP048387.1|WP_162650042.1|344787_345201_-|hypothetical-protein
MDFGDLKVGVETEIHNRTSFHELHYPSHFNIADEADLTIVYPSTLLFMNRVALGIPDEYCSTLVSHTLKPVVFSPAGFSRMYNNAATKRNVEWIKSDNAPNWHILDPIIENLNVVEEDYYTVPDVKSTIEFIEKLIK
>NZ_CP048387.1|WP_162649529.1|345808_346270_+|CinA-family-protein
MERLIEWAINNNYSISTCESFTGGAFSNALTNVSGSSKAYKGGFVCYSNEFKVDVLKIDIKVIKKYSPVSVEVLTEMLNKTQKILLTDIVIGYTGWAPPLDKKNSDSGLTYYGFKIKDEITIIEYKLEANMDRSHFKTIMIEKLIKQIEKRMI
>NZ_CP048387.1|WP_162649530.1|346306_347338_+|recombinase-RecA
MNFTKTQIEGNVIVPKDIFEDPDLKAVLKEIEKTHGKGSIMTLGDQIDSKVEVISSGSLLLDEIIGVGGYPKGRVIEIFGPESSGKTTLALHAIAEAQREGGIAAFIDAEHSLDPSYAKRIGVDIDNLIVSQPDSGEQGLEILEALVKSGKVSIVIVDSVAALVPKAELDGEMSDQQIGAQARLMSKALRKVNGIINKTNTVVIFINQLREKVGVIFGNPEVTPGGRALRFYSSLRLEVRKGETILQNGVATGNKAKIKVVKNKVSPPFKTCQILIQYNLGIDKMLEVIELGIQRNIIDKAGSWFSYNGEKIGQGKDSVKEFLNANPKAYEEISIKLKQNDIK
>NZ_CP048387.1|WP_162649532.1|347390_348935_+|HDIG-domain-containing-protein
MKMNYFLSTISIAEVSLISALIICFLIILVLVYTVYKTKNINKFETKNAQKKAKKIYFKIINDARIEKDEILNKAEIKKSDLLADIDLELKRISRLKEEIALEKNKQVRINQGFEEAQNSINNEKMKLNSEILKMVAELETVALMTKDEARDNLEKSIYKLHRDELNKSLNELENISEIKIKQAAQNILISAMQNVSVETTETYNLTFIEIKHEDMKGRIIGKEGRNIKAFQQYGGVDLVIDDGSTKVGISSLNPIRREIATRTLNKLLETGRLQPASIEEELIIQEEKIEQEMREIGQKTVDNLKLENINPRIKYLLGKLKFRSSYAQNVLGHSIEVAQISGLIAAELGLDIELATKCGLFHDIGKAVDFEGDGSHVKMGVNELVKLNEDKIIINAVESHHGDSRKESVYAEIVVIADSISAARIGARNNDIATFIARVKELEDECNKVEGVLKTYALQSGRQIRVIVDAEMINDIDMKRLSVEIENVINRVKKVPGTINVTLIKEKRLSISI
>NZ_CP048387.1|WP_162649533.1|348955_349918_+|LD-carboxypeptidase
MKIGIYTASTPIGFLSPKRSQRAIDFLNSKNHQVILGDLFWKSDSYRSGSIIERANEINQLLGSNIDILMSSIGGYNTSSILPFINTDSMSNKQLIVTGFSDSTSILYFFKSSLKNCRVLYGPALVPSFGDFESEFLHTTYESMMNRIQNKKIKYSEKSIYLWSDSKEGWEEETNLKIYQKNKWMTNCNVEEISGRLFGGNLNSIISSYNESWYPKIEEGDILLIEDSQKSIAEIERNISWIFDKGWHTKISAIILSKHELFDDLKSSRTSIDVLNEFMDIYNIKIPIIYNTDFGHTRPMIVLELFKNISINFLDKEITQ
>NZ_CP048387.1|WP_162649535.1|349991_351332_+|signal-recognition-particle-protein
MGFGDFLAKRFQKSIEKNLKKSQLNEENVSEALREIRLSLLEADVNIDVVKKIVSAIKEKSIGGFIEEGVRADQQMVKIVHEELINVLGKEKSELNISKKPSPIMMVGLQGAGKTTTVAKLTNLLKKQGKKVLMVALDIYRPGAIDQLVELATKNKFDVFEKGNQNPTKTAKEAMKFAEENKYDVVLLDTAGRLQIDKQLMGELKEIKKITSPTEIILTVDGMTGQDIINVATEFNSTLKITGVIVTKLDGDARGGATLSISYVTKVPIKFIGEGEGIDALSEFYPKRIADRIMGFGDVETLFEKATKQVDQRTMEKTMRRMMQGLFDLEDLKNQMAQLANMGNLGAVMKMMPGLNGKISEDQITTAQTKLKIAEYLMDSMTLKERRDPRLLKAINRKRRIIKGSGRTEKEFNELINQFEKSKKQALEMAKMFKSGRMPNLSNFGR

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Crispr_ID: NZ_CP048387_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP048387_5

375730-375878

Unclear

Consensus_repeat	Method
CAGCAGCTAAAAAACCAGCAGTGAAATCAACA	CRISPRCasFinder

2 spacers

cas3

The CRISPR arrays of NZ_CP048387_5

>merge|NZ_CP048387|5|375730-375878|CRISPRCasFinder
CTACAGCTAAAAAAACTGTTGCAAAACCAGCAGCTAAAAAACCAGCAGTGAAATCAACAACTGCAGCTAAACCAGCAGCGAAAAAACCAGCAGCTAAATCAGCACCAGCAGCTAGCACAGCAGCTAAAAAGCCAGCAGTGAAATCAACA

>NZ_CP048387|5|4|375730-375878|CRISPRCasFinder
CTACAGCTAAAAAAACTGTTGCAAAACCAGCA	GCTAAAAAACCAGCAGTGAAATCAA
CAACTGCAGCTAAACCAGCAGCGAAAAAACCA	GCAGCTAAATCAGCACCAGCAGCTAGCA
CAGCAGCTAAAAAGCCAGCAGTGAAATCAACA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP048387.1\|WP_162649552.1\|366475_367801_+\|methylenetetrahydrofolate--tRNA-(uracil(54)--C(5))-methyltransferase-(FADH(2)-oxidizing)-TrmFO	unknown	unknown	gnl\|CDD\|235416
NZ_CP048387.1\|WP_162649574.1\|382215_382953_+\|DUF3196-domain-containing-protein	unknown	unknown	unknown
NZ_CP048387.1\|WP_162649560.1\|371691_373314_-\|DEAD/DEAH-box-helicase	cas3	mkCas0139_cas3_CAS-I	gnl\|CDD\|223587
NZ_CP048387.1\|WP_162649573.1\|381707_382106_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048387.1\|WP_162649555.1\|369409_370288_+\|phosphatase-PAP2-family-protein	unknown	unknown	gnl\|CDD\|238813
NZ_CP048387.1\|WP_162649571.1\|378380_381506_+\|lipoprotein	unknown	unknown	gnl\|CDD\|119360
NZ_CP048387.1\|WP_162649558.1\|371319_371652_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048387.1\|WP_162649577.1\|384245_384968_+\|NAD(+)-synthase	unknown	unknown	gnl\|CDD\|238309
NZ_CP048387.1\|WP_162649566.1\|374427_375150_+\|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD	unknown	unknown	gnl\|CDD\|234581
NZ_CP048387.1\|WP_162649580.1\|385628_385886_+\|TIGR04561-family-membrane-protein	unknown	unknown	gnl\|CDD\|275354
NZ_CP048387.1\|WP_162649576.1\|382956_384243_+\|GTPase-ObgE	unknown	unknown	gnl\|CDD\|237046
NZ_CP048387.1\|WP_162649551.1\|363990_366414_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048387.1\|WP_162649582.1\|385919_387077_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048387.1\|WP_162649578.1\|384982_385480_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048387.1\|WP_162649568.1\|376050_376365_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048387.1\|WP_162649553.1\|367803_369420_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048387.1\|WP_162649569.1\|376502_378275_+\|PTS-transporter-subunit-EIIC	unknown	unknown	gnl\|CDD\|273920
NZ_CP048387.1\|WP_162649556.1\|370299_371052_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NZ_CP048387.1\|WP_162649564.1\|373933_374428_+\|16S-rRNA-processing-protein-RimM	unknown	unknown	gnl\|CDD\|234650
NZ_CP048387.1\|WP_162649562.1\|373529_373934_+\|30S-ribosomal-protein-S16	unknown	unknown	gnl\|CDD\|234588

Protein	Function_ID	Function_description	E-value
NZ_CP048387.1\|WP_162649552.1\|366475_367801_+\|methylenetetrahydrofolate--tRNA-(uracil(54)--C(5))-methyltransferase-(FADH(2)-oxidizing)-TrmFO	gnl\|CDD\|235416	PRK05335, PRK05335, tRNA (uracil-5-)-methyltransferase Gid; Reviewed.	0
NZ_CP048387.1\|WP_162649560.1\|371691_373314_-\|DEAD/DEAH-box-helicase	gnl\|CDD\|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	2.6911e-137
NZ_CP048387.1\|WP_162649555.1\|369409_370288_+\|phosphatase-PAP2-family-protein	gnl\|CDD\|238813	cd01610, PAP2_like, PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid phosphatase, vanadium chloroperoxidases, vanadium bromoperoxidases, and several other mostly uncharacterized subfamilies. Several members of this superfamily have been predicted to be transmembrane proteins.	8.61874e-17
NZ_CP048387.1\|WP_162649569.1\|376502_378275_+\|PTS-transporter-subunit-EIIC	gnl\|CDD\|273920	TIGR01998, N-acetylglucosamine_and_glucose_PTS, PTS system, N-acetylglucosamine-specific IIBC component. This model represents the combined B and C domains of the PTS transport system enzyme II specific for N-acetylglucosamine transport. Many of the genes in this family also include an A domain as part of the same polypeptide and thus should be given the name "PTS system, N-acetylglucosamine-specific IIABC component". This family is most closely related to the glucose-specific PTS enzymes. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	1.65793e-114
NZ_CP048387.1\|WP_162649566.1\|374427_375150_+\|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD	gnl\|CDD\|234581	PRK00026, trmD, tRNA (guanine-N(1)-)-methyltransferase; Reviewed.	2.39872e-121
NZ_CP048387.1\|WP_162649580.1\|385628_385886_+\|TIGR04561-family-membrane-protein	gnl\|CDD\|275354	TIGR04561, hypothetical_protein_SCULI_v1c03640, integral membrane protein. Members of this protein are short (about 85-residue), low-complexity sequences of unknown function, with a highly hydrophobic N-terminal region of about 40 amino acids followed by a charged (Asp, Glu, Lys, and Arg-rich), sometimes repetitive C-terminal region. Members occur exclusively among the Mollicutes (Mycoplasma, Mesoplasma, Acholeplasma, Spiroplasma, Entomoplasma). The gene neighborhood of this protein is not conserved.	9.13363e-06
NZ_CP048387.1\|WP_162649576.1\|382956_384243_+\|GTPase-ObgE	gnl\|CDD\|237046	PRK12297, obgE, GTPase CgtA; Reviewed.	0
NZ_CP048387.1\|WP_162649571.1\|378380_381506_+\|lipoprotein	gnl\|CDD\|119360	cd06543, GH18_PF-ChiA-like, PF-ChiA is an uncharacterized chitinase found in the hyperthermophilic archaeon Pyrococcus furiosus with a glycosyl hydrolase family 18 (GH18) catalytic domain as well as a cellulose-binding domain. Members of this domain family are found not only in archaea but also in eukaryotes and prokaryotes. PF-ChiA exhibits hydrolytic activity toward both colloidal and crystalline (beta/alpha) chitins at high temperature.	4.4169e-45
NZ_CP048387.1\|WP_162649577.1\|384245_384968_+\|NAD(+)-synthase	gnl\|CDD\|238309	cd00553, NAD_synthase, NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD+ occurs via an NAD-adenylate intermediate and requires ATP and Mg2+. The intemediate is subsequently cleaved into NAD+ and AMP. In many prokaryotes, such as E. coli , NAD synthetase consists of a single domain and is strictly ammonia dependent. In contrast, eukaryotes and other prokaryotes have an additional N-terminal amidohydrolase domain that prefer glutamine, Interestingly, NAD+ synthases in these prokaryotes, can also utilize ammonia as an amide source .	1.72652e-83
NZ_CP048387.1\|WP_162649556.1\|370299_371052_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	2.04186e-13
NZ_CP048387.1\|WP_162649564.1\|373933_374428_+\|16S-rRNA-processing-protein-RimM	gnl\|CDD\|234650	PRK00122, rimM, 16S rRNA-processing protein RimM; Provisional.	1.28161e-18
NZ_CP048387.1\|WP_162649562.1\|373529_373934_+\|30S-ribosomal-protein-S16	gnl\|CDD\|234588	PRK00040, rpsP, 30S ribosomal protein S16; Reviewed.	1.48433e-31

>NZ_CP048387.1|WP_162649566.1|374427_375150_+|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD
MKISILTLFPNLISNYISESIIKRAILKNKVELEVIDIREHTTYDHKQVDDYQFGGGAGMLLMIEPVVRALNSIKTKESFTILTSPQGVTLNNYISRELSIKHKHIILICGHYEGIDARIMNYVDMELSIGDYVITGGELSSLVIADSIIRLIDGVIAKESHENDSFENNLLDYDSYTKPVEFDGHKVPEVLISGHHKNINNFRRESQLKNTFNKRNDLLKKAKLSSEDQMIIEKLKRGE
>NZ_CP048387.1|WP_162649564.1|373933_374428_+|16S-rRNA-processing-protein-RimM
MIKDNLALVGKIAGTHGIKGELKVYWFTETKDIDIKINDFVFVKNESTFDVFKIRQLTDLYIKKPLIQFDEYENINHVQKLVGKEIYIKKELVTELDDYSCLGFDAIFENKKGKVIDFLDNSIYMTYKVEFKDKTIWIPGVDDYLKEIDFDNQKITFINIEGLA
>NZ_CP048387.1|WP_162649562.1|373529_373934_+|30S-ribosomal-protein-S16
MVKLRLRRAGKKRAAFFRIVATDSRVQRDGIYIDLIGTYNPINGETKINEEIALKWLADGAQPTDTVRDILSKHGIMKKFHDSKLDKPAKAKKAVVKKPAAKKPATVKKPTTAKPATAKKPAAKPAAAKAPAKK
>NZ_CP048387.1|WP_162649560.1|371691_373314_-|DEAD/DEAH-box-helicase
MTFKELIKNDRVLKSLEIMDFTTPTDIQQQAIPMFLEGKNIFGKSSTGTGKTAAFALPILEKLDIKNRKPQALIVTPTRELASQIIDVIRKLTSRYEGVKLTSLIGGAEIRKQLLSLRDTHIIVGTPGRINDHIIRRSFNFDNIKTIILDEADEMLKMGFKNEIDEIFHRASPEVQIGLFSATTSDKVMSLAYNYMKQYETIIVDNAVKVNDNIDNRFIYVPRNKKVDLLLSIFEKHKPQAAIIFSNTKSNTDNILDTLRDNNITGVVINGDKRQSERTRAINRFRKGEVQVLIATDVAARGIDIKGVDLVINFDIPRDNEYIIHRIGRTGRNGEKGSAISIVDGRGTLKQIKEIEHEYKIEIYEVDPSEYGIEKGSSSDRGSRDDRGSRGGSYGGSRDRGSRGGSSSYGGSRDRSSRGGSYGGSRDRGSRGGSYGGSRDGGSRGGSYESRDRQPRSDDSQSRNTSGSFKSNAYPSSEAPRDRDRGSFGGSRDRGSFGGSRGGSRDRGSFGGRYSSPKPTGPNRKERRAALQSKADFIEE
>NZ_CP048387.1|WP_162649558.1|371319_371652_+|hypothetical-protein
MQPTMCYQCGINPGTRQNVIMSTHKHGGIIRETKYSTSSTNVLICEMCELKNSLPRITMLFIIVNLFLILFTFGIWTLVTVLMIYLKFKKKKQILLQKENLISFGLKPTF
>NZ_CP048387.1|WP_162649556.1|370299_371052_-|class-I-SAM-dependent-methyltransferase
MNKNNYSSLSSIVYDFTKPPGTNSDGDIEFYKSYLLPLEGKILEAGVGNGRMSIPLLKYGLSVDGIDISKEMLDIYKYNLDKQKLSGKIINMNLKEYVSDNYYEAIIMPTGSVCMIEEVEDLKIILNNFYKSLSNNGFILIDFIYPTTFKPGSYHKTNIQLDSENSIELNINHKSIDWSKQVAYSTNQYIQFQNGKEIKTEIQNFNLRWYSENEIKMLAEKAGYKSIELIKNYNKKRVLNLNTITLFAKK
>NZ_CP048387.1|WP_162649555.1|369409_370288_+|phosphatase-PAP2-family-protein
MKSSLFKKYWPLIFIELILLILLILFGIFDFEISSSFETYKNWLSVGFDVWGKKAVMVPIGVTIIFACVALGNRARNKNIFMYSMIGLAISTNITLALFLFDYKDFSLHNKNKTEIITAISMYIILAICILSFILTTLLINKLSIFKSKMYMSTLMSKVIYAIVFMLITTLIVSVLKLLVGRPRPRDVIGDGVDFKYIFQFYFGQDRGKSFPSGHTQAASLFLVLVYFVPISKKENIFKILFYIIAICSIVLTAISRVLIHAHFPTDVTFSIILSSLCFAFIPKLINFIIKK
>NZ_CP048387.1|WP_162649553.1|367803_369420_+|hypothetical-protein
MSNISENKNFRFYSPDQNNSLFWFSLHYMVKRDPELQYIVNTRKKELFSLYQVCHLGIVQYMLYRGICLEVISTNDMKEYSDYILENYDNLFALRYKTIPSKQRPEKIKFETPQERKEVAQMITSICFPHINEYCFLEHDSWKNLSRAYIAELAHKMHYDINHIFDDDFKVSEVYPFLFVLNLINNIDAQNLYTNVSKAFIPEKIIEKYNRGRKWFSKEVEYLKTTMEIISNPDEFRIFLGNFEYEKWITFTRQEKVKAIFELTKMVAILMKDKIARITMLKEGQDAFEILEEYIPIFVPSDKDEGVRSIFKRNEDIVVLSPFTYQNVNPLSLTRYIESKGDYHVKVNEKKLYHYSQIVLSVFSKLRITLLTYPLFPEYINKTVIEPKREIWVDILNIFKEKDNILVPTMEHYELTVDDFVIDEHEIEYMEKHKGTKLSGVEKDHAIRKMGLILNLIIGLNRPTLKLFENNIEDLLKYTFIIFGPHPINRTVQTTENIEIALNRFKRYIKLFKSASKSEVKKYGIYFELPAKLFKNEK
>NZ_CP048387.1|WP_162649552.1|366475_367801_+|methylenetetrahydrofolate--tRNA-(uracil(54)--C(5))-methyltransferase-(FADH(2)-oxidizing)-TrmFO
MKKYVNIIGAGLAGCEAAYQLSKRKIYVNLYEVKGIKRNPVQTMDTFAELVCSNTLRSTEPANAVGTLKLEMQKFDSLILKAAYSAQLPAGGSLAVDREIFSGFIDNEIRNNEYINVISEDVGDIDPNQITIVASGPLTTPKLQTGIQKLVGSDYFYFFDAVAPIVKLDSLDMNKLYWKNRYDKGETKDYLNAPMTKHEYEKFLEELLNSEKAEMHLKDEESLRVFEGCMPVEVMASRGKETLLYGPLKPVGLYRSKEDKELHAVVQLRQDNAAKDLFNLVGFQTNLKWGEQKRVFRMIPGLENAEFIRYGVMHKNNFINSPTLLNKHMQMKSNPNIFFAGQITGVEGYVESTSSGIIAAVNVARKIEEKELIEWPDTTVMGALINYICITSPENFQPMKANWQIVNTEGLNKKMKKILKKEQYSIKALKDIEEFINKYKI
>NZ_CP048387.1|WP_162649551.1|363990_366414_+|hypothetical-protein
MKTLNKIILVILLASSSFFGALNFIDNKNIQTTPKNINTNESDLSDLRFIKAFTNYIYLHVKGLEDELNYLKNAILQNSKLDKTFTEELKTKDSYFFDSYFLSFILLNSEYGLGVHSGEYSAELFNFWINTPEQSRNLFWVLVDFFYINVVPKIINKNDKEIELILEDTLNVPGLTVNLKDIKKGDNFIDFFVNENISPAWPKIQMSISSASHVWHTEGTDYNFSRKNEKAFEFDNKWVPDEEIEKITNKLNLIFWTRGKPIRSDDFINNFTFNTFEELNTNLKEATKFYIDGADYYGVNLKDAIYSYINTNNDLWNNANSSTYINLDYAFQKISNKFLISFNYLFYVYKSIFKNKNDDSYLHLIKSIIFHSKKTEKIPNGKVIGLNSDSTYGLEIQINFNLLSVPNNNSLISFDNFQLATTTVHEIGHVVDLLVTDFDWTNGNNKLINFNENTYKLLVEWEPNITEAFGVDVKKNKLDEVQNKRKNEINKYSNLDTPTLIMNIANPDELYYKIREEMQSYIMKFKDDMWAEGKDLSKVVKNSYIKYGDKYLDEAITEIMKSYNDGESKVYNLKLTPYYEFEDSIDLNFNVINTKKELKNLSEIKIDDQVIDLNDDKEQSIELVTELINKQLISNDLTNMNWTIIENGKFTNIEDIDFENGNSLKVLVTDNDQKYSGYIMFDINYSLKINLSNLITDKHLGDVNTKNSNELLKIIESKYPIIKGEIDIDYNYPIGKNEIAIKAKSESKYYGIIVFTFNYIDNEIGPNPLPGDNEGNSLEVIVIAVIISAIVIIIITGIVIIIRKRKQ
>NZ_CP048387.1|WP_162649568.1|376050_376365_+|hypothetical-protein
MLNLFSFLKNSEETSGKELTHSAALTVLIIGIICIVAAAVLFYFFILHIKRSSFKEKQHAEQFRRAFWWDEPMKFWSFYVYAFMCISLILGFIVCLIISIPVLV
>NZ_CP048387.1|WP_162649569.1|376502_378275_+|PTS-transporter-subunit-EIIC
MTAHKEDMLNTKKNGVSGWSKFLTVLQELGKALQFPVAVLPFAAILNRFGALGITYTTGAEGEITNAIGYWISYIIQKPGSVAFDQLPLLFAIGISFGLAKDHRGEVTMVAAIMYFIIILMTSEHGIPEMLYGNVLTKTVYNADGTEIIGQYSSLMYVFTETQVQGVAVITGATYVLNVGVLGGVVSGVVAAMLYNKFKEIKLPAALSFFGGRRFVPMIGIVAAMGLVAIFAILWPWIQLVLMLMGQAVADPNNPAVAIPGTGLYAFLNRLLLPFGLHQILNTFFWFQMPIKGEIIAPITGEIIPPIDGGTFTWINGDINAFAKGLNTSGLFQSGYFPIMMGGVPAIAAAMIFASKKDRRTEVMGFLGGVALVSFVSGITEPVEFSFVFLSPVLLLVHAGMSAIFMMITTAMQIQIGFGFSAGFIDYAVSFAQSWGLSTYKGGAMEVVSNPLMMLPLIAAAGGAYFVVFSLLIRKLNIQTPGREEDGGYVSAPVDITTTSSKDSGSKADKYETAAAKFIAAIGSDNLESIDNCATRLRLVLKDNKNIDVAAIKATGVSFGIKQLGDQALQIVIGPDVEHYANAMKRIKNV
>NZ_CP048387.1|WP_162649571.1|378380_381506_+|lipoprotein
MKKLLSILSTITLVGASTTTIIACSPQNDIFPSGENSWWNNTETGFNDSNVINKMMNKVSRSNEGDKILTQDQGEGVSNFKKSLKDKNNNGLLKSTLAGKNKNILDDSLLIKNAKDIRFKPYADIGIVEDYAEYALKWHNKSGAWRSEVIKEAEKLGIDNVNFNNLANIVNNKDLINLDNGGGINLGFMQNASDTGELTPMWDAAPSKTTNKSEEWFKDRFDKWSKDSNGNISKNMTISFGPFANSFWHTAYNNGSTAEQLAEQLKMIGENYNSKSFDFYFAAPYLSAKQPQYKESQKLLASALKILMETDAAENNGKTTWDIRLSLVGSNVQGLGFSPSMLEGNEAGFEEHNADESSPLYVFTKYLGTNFKLNLVAGYLSEEDSELYPNNLEKLKNNENWELKFIKNQIQVLRNNWIKLSNVLNGTEFEQSKLNWNQSTGIVNEEQPPLTDDEKDFSKRMIVTPWMGARAEKAMYNFTPKDMAELREFSIEQNIGELSMFYITRDHGSEFLSSLTEDEKNNLSTTNSARLADKNALDQNIRSGSGFYDEYSYTKALNGKLSKSDVENLKHYDTFEEAKINGIKGLIDLESIKVESEFGKFVGSLGNDAVWEGPGNGGPGTGENGGNTDPVPPTGEQGPAPASPSLYKDRLLANPVRGNSQITKKVAKNSGVYFSPYLDAGLWEGNEIAAIKGASNLDHLTLSFAQQINSKQPSNPSEDMEISFAGIDKGNEGYDYWLEAQLKAKVLDPLVKQNPDNLKNIKVAYGGATTGGYDHKNPWSLAAELYGNDATNRLEKSLVDFQNEISGLYGKSNIMKSIDFDIEGEAQNNHEGITVLAKTLAQMKKADKSWDFSITLPVLPQGLTNVGYGVLDIFVKEYKNAGLDIKDLPITNLMLMDYGDPIYLEAISKNETNFDLAKAAIENTFRNIENSIKENFNIEGVKPSNIWKLIGATPMIGVNDTVAGVFTEEDAKELYNYAHTVGLGYIGMWSMNDDRGRQGDKAINKSLVTHGLAYLDEYVFASAFNGNWDYVKKHTHDKWYL
>NZ_CP048387.1|WP_162649573.1|381707_382106_+|hypothetical-protein
MLKSRRHLIKILIIFTLTVMFAGGLGADWNSARGIVWTMFYIVLPIFVLIGSILGLIFERNKLLQRLVFVATWVYALIGIIFVILGIWDLVDNIIENGEMGDTLLSLIHTVLFALIWWIAACFGLTAYKSMK
>NZ_CP048387.1|WP_162649574.1|382215_382953_+|DUF3196-domain-containing-protein
MNNYYLETIELIKKLINDSKIEEALQILEDELNAPYIPRDYEFEFKQLLTSIIDVKRTKEQKILNDPWSKEKVIDVLSKNGDHELHIVAIGKIKDLNARSFTDFFVGYFSNKENLWMSKMYALLTFANQGIDMDFKIVDNLKEVVLNPSKINTKEYDNSFAKLKSNLEKSAGSNDIMLTNFSNQLLTEYYFINFPNKIDDNNINDIVLFILNSCNKMFNIKNFSELKNKELEKQLEKEFKNAGIL
>NZ_CP048387.1|WP_162649576.1|382956_384243_+|GTPase-ObgE
MKFVDLANFVIKSGNGGNGAVSFRRELYVANGGPNGGDGGKGGDVIFAVDEGKSSLLDLKLQKFYTAQNGDHGDIKNMYGKGGEDILLYVPLGTTIYNHKTGAKIADFTSKDQRQVVALGGKGGRGNAKFANSRNKAPTIYENGDPGVEIEIRAELKVLADVGFVGLPNAGKSTMLRAISNSKPVIADYPFTTLNPQLGVSRDNLGRTFVVADLPGLIEGASLGKGLGIEFLKHIERCKIVCHVIDMTGNYGTEDVIKNYEMIRNELKSYRVDLTNRPEIIIANKIDEEEGQINALYFKEKYKDKVIVETSGLKKQGIEKLLLTIGDTLEEYKDKTFDTEETKELFKVYTFEDPDGDIIVSNLGNGKWSLSGETIYRVYQKTPTTTYDNLLLFNEKLKKLGVYDTLRERGAKKGDLIQLFDVEFEWMD
>NZ_CP048387.1|WP_162649577.1|384245_384968_+|NAD(+)-synthase
MDLKQYIDYIGTWLQEQVKLANAKGVIVGLSGGIDSALVASIAQKAFPNNHQTVWMDCESSKFDYECAHELINFKKFHNVDVDLTSTYKDLISELDSKIKLSDLSKANAKARLRMTTLYAIGQTKNYLVLGTDNADEWHIGYFTKFGDGGVDLLPIVHLLKGEVKDAARLMEVCDSIINRAPSAGLWDNQTDEEEIGVSYDEIDDYLSGKKISEKSKQRIDYLHKISNHKRVGAPAPSKK
>NZ_CP048387.1|WP_162649578.1|384982_385480_+|hypothetical-protein
MTELQASKISEFLEKKISEEEMDLVFEDLVSMISLYLATTLFGLDINRLYMEGIENNTPIEDIIKQAQHEILLSKSEISEHLQIIFEDEERSEMFATGCVESGVYDFELPNSLQKFLDEQQVSKDDYIVEMIISFQSEFYDFFTTEVNVEEWKDEIIEQILLNWE
>NZ_CP048387.1|WP_162649580.1|385628_385886_+|TIGR04561-family-membrane-protein
MNSKSVIFKILDLEIPLWVFIIIFIIIGLFALAIYLLSLFKVKKEIVYNNKKISIHEYDQIRAINLQKEDFEMEVSKVLSTINKK
>NZ_CP048387.1|WP_162649582.1|385919_387077_+|hypothetical-protein
MALFNSLLKKQNSNNQAALDNSAFYSYPSNEVKEVSQFEVQKYYQPPVVRQRKQFQVQDGYSQRPMDEFIEEFNVPVNNPYQHINQEAIPIQSTSMGYVNGNQFQVNNNYMIQQEQYLSRDNQMQVGQIAPTNEIPAAIAHEIRSEKLKQFIIFVLSFSGAITSTLFLMSYYNEELMGISKNSVLHPILSIPILLISTMFILLTISDSTLLSRSMTKYRSDLANGIDSVPYFLTKNYKNFTRRGVYVNWMSFSVYIVGVILLLIFYGLQAQYNSGQKSFYIFFWRVAELKSLVSEIVMTTIVLVGALIVHITHIVWTKSRKNNIIGYYGHEIVHPAELAQIKKTANIKCAIITFIVLAILLFVLFIPWLIIRKKGGKPVMPIGRI

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP048387_5	5.1\|375762\|25\|NZ_CP048387\|CRISPRCasFinder	375762-375786	25	MN693868	Marine virus AFVG_250M1130, complete genome	1426-1450	3	0.88
NZ_CP048387_5	5.2\|375819\|28\|NZ_CP048387\|CRISPRCasFinder	375819-375846	28	NZ_CP049229	Lactobacillus iners strain C0210C1 plasmid pC0210C1, complete sequence	85076-85103	4	0.857
NZ_CP048387_5	5.2\|375819\|28\|NZ_CP048387\|CRISPRCasFinder	375819-375846	28	NZ_CP049227	Lactobacillus iners strain C0011D1 plasmid pC0011D1, complete sequence	93831-93858	4	0.857
NZ_CP048387_5	5.2\|375819\|28\|NZ_CP048387\|CRISPRCasFinder	375819-375846	28	NZ_CP049224	Lactobacillus iners strain C0094A1 plasmid pC0094A1, complete sequence	8091-8118	4	0.857
NZ_CP048387_5	5.2\|375819\|28\|NZ_CP048387\|CRISPRCasFinder	375819-375846	28	MN694706	Marine virus AFVG_250M574, complete genome	32297-32324	5	0.821
NZ_CP048387_5	5.2\|375819\|28\|NZ_CP048387\|CRISPRCasFinder	375819-375846	28	NC_017236	Borreliella afzelii PKo plasmid lp28-8, complete sequence	18388-18415	5	0.821
NZ_CP048387_5	5.2\|375819\|28\|NZ_CP048387\|CRISPRCasFinder	375819-375846	28	MN693076	Marine virus AFVG_25M561, complete genome	17557-17584	6	0.786
NZ_CP048387_5	5.2\|375819\|28\|NZ_CP048387\|CRISPRCasFinder	375819-375846	28	NC_029057	Vibrio phage qdvp001, partial genome	69976-70003	6	0.786
NZ_CP048387_1	1.1\|193697\|34\|NZ_CP048387\|PILER-CR	193697-193730	34	NC_014824	Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence	117719-117752	7	0.794
NZ_CP048387_3	3.3\|324993\|31\|NZ_CP048387\|CRT	324993-325023	31	NC_019521	Sphingomonas phage PAU, complete genome	134806-134836	7	0.774
NZ_CP048387_5	5.2\|375819\|28\|NZ_CP048387\|CRISPRCasFinder	375819-375846	28	NZ_CP013125	Pseudomonas mendocina S5.2 plasmid pPME5, complete sequence	165609-165636	7	0.75
NZ_CP048387_5	5.2\|375819\|28\|NZ_CP048387\|CRISPRCasFinder	375819-375846	28	MH791415	UNVERIFIED: Enterococcus phage EfsWh-1, complete genome	15460-15487	7	0.75
NZ_CP048387_5	5.2\|375819\|28\|NZ_CP048387\|CRISPRCasFinder	375819-375846	28	NC_018086	Enterococcus phage BC-611, complete genome	10554-10581	7	0.75
NZ_CP048387_5	5.2\|375819\|28\|NZ_CP048387\|CRISPRCasFinder	375819-375846	28	AB712291	Enterococcus phage BC-611 DNA, complete genome	10554-10581	7	0.75
NZ_CP048387_5	5.2\|375819\|28\|NZ_CP048387\|CRISPRCasFinder	375819-375846	28	MN871443	UNVERIFIED: Enterococcus phage EfsWh_1, complete genome	15460-15487	7	0.75
NZ_CP048387_5	5.2\|375819\|28\|NZ_CP048387\|CRISPRCasFinder	375819-375846	28	MK800154	Enterococcus phage Entf1, complete genome	16625-16652	7	0.75
NZ_CP048387_5	5.2\|375819\|28\|NZ_CP048387\|CRISPRCasFinder	375819-375846	28	MH618488	Enterococcus phage vB_EfaS_HEf13, complete genome	41450-41477	7	0.75
NZ_CP048387_5	5.2\|375819\|28\|NZ_CP048387\|CRISPRCasFinder	375819-375846	28	LC547238	Entercoccus phage phiM1EF2 DNA, nearly complete genome	45968-45995	7	0.75
NZ_CP048387_5	5.2\|375819\|28\|NZ_CP048387\|CRISPRCasFinder	375819-375846	28	KY303907	Enterococcus phage EF-P29, complete genome	45104-45131	7	0.75
NZ_CP048387_5	5.2\|375819\|28\|NZ_CP048387\|CRISPRCasFinder	375819-375846	28	NC_041960	Enterococcus phage SAP6, complete genome	1601-1628	7	0.75
NZ_CP048387_5	5.2\|375819\|28\|NZ_CP048387\|CRISPRCasFinder	375819-375846	28	MK570225	Enterococcus phage vB_EfaS_PHB08, complete genome	43026-43053	7	0.75
NZ_CP048387_5	5.2\|375819\|28\|NZ_CP048387\|CRISPRCasFinder	375819-375846	28	MN693142	Marine virus AFVG_25M544, complete genome	10713-10740	7	0.75
NZ_CP048387_5	5.2\|375819\|28\|NZ_CP048387\|CRISPRCasFinder	375819-375846	28	NC_041959	Enterococcus phage IME-EF1, complete genome	1601-1628	7	0.75
NZ_CP048387_1	1.1\|193697\|34\|NZ_CP048387\|PILER-CR	193697-193730	34	NC_014824	Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence	117641-117674	8	0.765
NZ_CP048387_1	1.4\|193927\|34\|NZ_CP048387\|PILER-CR	193927-193960	34	MK288021	Bacillus phage pW2, complete genome	143643-143676	8	0.765
NZ_CP048387_3	3.3\|324993\|31\|NZ_CP048387\|CRT	324993-325023	31	AJ972879	Yersinia phage phiR1-37 complete genome	190153-190183	8	0.742
NZ_CP048387_3	3.3\|324993\|31\|NZ_CP048387\|CRT	324993-325023	31	NC_016163	Yersinia phage phiR1-37, complete genome	190153-190183	8	0.742
NZ_CP048387_3	3.5\|325140\|34\|NZ_CP048387\|CRT	325140-325173	34	NZ_CP038863	Campylobacter jejuni strain SCJK2 plasmid unnamed1, complete sequence	70620-70653	8	0.765
NZ_CP048387_1	1.4\|193927\|34\|NZ_CP048387\|PILER-CR	193927-193960	34	NC_014824	Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence	117641-117674	9	0.735
NZ_CP048387_3	3.8\|325140\|39\|NZ_CP048387\|CRISPRCasFinder	325140-325178	39	NZ_CP038863	Campylobacter jejuni strain SCJK2 plasmid unnamed1, complete sequence	70620-70658	9	0.769
NZ_CP048387_1	1.4\|193927\|34\|NZ_CP048387\|PILER-CR	193927-193960	34	NZ_CP030933	Enterococcus gilvus strain CR1 plasmid pCR1A, complete sequence	626310-626343	10	0.706
NZ_CP048387_1	1.4\|193927\|34\|NZ_CP048387\|PILER-CR	193927-193960	34	NC_014824	Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence	117719-117752	10	0.706

1. spacer 5.1|375762|25|NZ_CP048387|CRISPRCasFinder matches to MN693868 (Marine virus AFVG_250M1130, complete genome) position: , mismatch: 3, identity: 0.88

gctaaaaaaccagcagtgaaatcaa	CRISPR spacer
gctaaaaaaccatcactgaaatcca	Protospacer
************ ** ******* *

2. spacer 5.2|375819|28|NZ_CP048387|CRISPRCasFinder matches to NZ_CP049229 (Lactobacillus iners strain C0210C1 plasmid pC0210C1, complete sequence) position: , mismatch: 4, identity: 0.857

gcagctaaatcagcaccagcagctagca	CRISPR spacer
gcagctaatgcagcaccagcagctaaaa	Protospacer
********  ***************. *

3. spacer 5.2|375819|28|NZ_CP048387|CRISPRCasFinder matches to NZ_CP049227 (Lactobacillus iners strain C0011D1 plasmid pC0011D1, complete sequence) position: , mismatch: 4, identity: 0.857

gcagctaaatcagcaccagcagctagca	CRISPR spacer
gcagctaatgcagcaccagcagctaaaa	Protospacer
********  ***************. *

4. spacer 5.2|375819|28|NZ_CP048387|CRISPRCasFinder matches to NZ_CP049224 (Lactobacillus iners strain C0094A1 plasmid pC0094A1, complete sequence) position: , mismatch: 4, identity: 0.857

gcagctaaatcagcaccagcagctagca	CRISPR spacer
gcagctaatgcagcaccagcagctaaaa	Protospacer
********  ***************. *

5. spacer 5.2|375819|28|NZ_CP048387|CRISPRCasFinder matches to MN694706 (Marine virus AFVG_250M574, complete genome) position: , mismatch: 5, identity: 0.821

gcagctaaatcagcaccagcagctagca	CRISPR spacer
gcagctaaatcagcaccaggaactccta	Protospacer
******************* *.**  .*

6. spacer 5.2|375819|28|NZ_CP048387|CRISPRCasFinder matches to NC_017236 (Borreliella afzelii PKo plasmid lp28-8, complete sequence) position: , mismatch: 5, identity: 0.821

gcagctaaatcagcaccagcagctagca-	CRISPR spacer
gcagcaacatcagcaccagcagc-attac	Protospacer
***** * *************** * .*

7. spacer 5.2|375819|28|NZ_CP048387|CRISPRCasFinder matches to MN693076 (Marine virus AFVG_25M561, complete genome) position: , mismatch: 6, identity: 0.786

gcagctaaatcagcaccagcagctagca	CRISPR spacer
gcagctaattcagcaacagcagcagcga	Protospacer
******** ****** ******* .  *

8. spacer 5.2|375819|28|NZ_CP048387|CRISPRCasFinder matches to NC_029057 (Vibrio phage qdvp001, partial genome) position: , mismatch: 6, identity: 0.786

gcagctaaatcagcaccagcagctagca	CRISPR spacer
gcagctaggtcagcaccagcagcaactt	Protospacer
*******..************** * .

9. spacer 1.1|193697|34|NZ_CP048387|PILER-CR matches to NC_014824 (Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence) position: , mismatch: 7, identity: 0.794

taacagatatgagttctatgttttattgagctac	CRISPR spacer
tcacagatatgagctatatgttttattggtgtaa	Protospacer
* ***********.* ************.  **

10. spacer 3.3|324993|31|NZ_CP048387|CRT matches to NC_019521 (Sphingomonas phage PAU, complete genome) position: , mismatch: 7, identity: 0.774

taaaatgaattatgtattctataggactcaa----	CRISPR spacer
taaaaggaaatatgtattctata----tcatagtt	Protospacer
***** *** *************    ***

11. spacer 5.2|375819|28|NZ_CP048387|CRISPRCasFinder matches to NZ_CP013125 (Pseudomonas mendocina S5.2 plasmid pPME5, complete sequence) position: , mismatch: 7, identity: 0.75

gcagctaaatcagcaccagcagctagca	CRISPR spacer
ccagctaaaccagcaccagcaggagggt	Protospacer
 ********.************  .*

12. spacer 5.2|375819|28|NZ_CP048387|CRISPRCasFinder matches to MH791415 (UNVERIFIED: Enterococcus phage EfsWh-1, complete genome) position: , mismatch: 7, identity: 0.75

gcagctaaatcagcaccagcagctagca	CRISPR spacer
gcagctaaagcagcaccagcaaacactg	Protospacer
********* ***********. .* ..

13. spacer 5.2|375819|28|NZ_CP048387|CRISPRCasFinder matches to NC_018086 (Enterococcus phage BC-611, complete genome) position: , mismatch: 7, identity: 0.75

gcagctaaatcagcaccagcagctagca	CRISPR spacer
gcagctaaagcagcaccagcaaacactg	Protospacer
********* ***********. .* ..

14. spacer 5.2|375819|28|NZ_CP048387|CRISPRCasFinder matches to AB712291 (Enterococcus phage BC-611 DNA, complete genome) position: , mismatch: 7, identity: 0.75

gcagctaaatcagcaccagcagctagca	CRISPR spacer
gcagctaaagcagcaccagcaaacactg	Protospacer
********* ***********. .* ..

15. spacer 5.2|375819|28|NZ_CP048387|CRISPRCasFinder matches to MN871443 (UNVERIFIED: Enterococcus phage EfsWh_1, complete genome) position: , mismatch: 7, identity: 0.75

gcagctaaatcagcaccagcagctagca	CRISPR spacer
gcagctaaagcagcaccagcaaacactg	Protospacer
********* ***********. .* ..

16. spacer 5.2|375819|28|NZ_CP048387|CRISPRCasFinder matches to MK800154 (Enterococcus phage Entf1, complete genome) position: , mismatch: 7, identity: 0.75

gcagctaaatcagcaccagcagctagca	CRISPR spacer
gcagctaaagcagcaccagcaaacactg	Protospacer
********* ***********. .* ..

17. spacer 5.2|375819|28|NZ_CP048387|CRISPRCasFinder matches to MH618488 (Enterococcus phage vB_EfaS_HEf13, complete genome) position: , mismatch: 7, identity: 0.75

gcagctaaatcagcaccagcagctagca	CRISPR spacer
gcagctaaagcagcaccagcaaacactg	Protospacer
********* ***********. .* ..

18. spacer 5.2|375819|28|NZ_CP048387|CRISPRCasFinder matches to LC547238 (Entercoccus phage phiM1EF2 DNA, nearly complete genome) position: , mismatch: 7, identity: 0.75

gcagctaaatcagcaccagcagctagca	CRISPR spacer
gcagctaaagcagcaccagcaaacactg	Protospacer
********* ***********. .* ..

19. spacer 5.2|375819|28|NZ_CP048387|CRISPRCasFinder matches to KY303907 (Enterococcus phage EF-P29, complete genome) position: , mismatch: 7, identity: 0.75

gcagctaaatcagcaccagcagctagca	CRISPR spacer
gcagctaaagcagcaccagcaaacactg	Protospacer
********* ***********. .* ..

20. spacer 5.2|375819|28|NZ_CP048387|CRISPRCasFinder matches to NC_041960 (Enterococcus phage SAP6, complete genome) position: , mismatch: 7, identity: 0.75

gcagctaaatcagcaccagcagctagca	CRISPR spacer
gcagctaaagcagcaccagcaaacactg	Protospacer
********* ***********. .* ..

21. spacer 5.2|375819|28|NZ_CP048387|CRISPRCasFinder matches to MK570225 (Enterococcus phage vB_EfaS_PHB08, complete genome) position: , mismatch: 7, identity: 0.75

gcagctaaatcagcaccagcagctagca	CRISPR spacer
gcagctaaagcagcaccagcaaacactg	Protospacer
********* ***********. .* ..

22. spacer 5.2|375819|28|NZ_CP048387|CRISPRCasFinder matches to MN693142 (Marine virus AFVG_25M544, complete genome) position: , mismatch: 7, identity: 0.75

gcagctaaatcagcaccagcagctagca	CRISPR spacer
tttgctaaatcagcaacagcagctttta	Protospacer
 . ************ ********  .*

23. spacer 5.2|375819|28|NZ_CP048387|CRISPRCasFinder matches to NC_041959 (Enterococcus phage IME-EF1, complete genome) position: , mismatch: 7, identity: 0.75

gcagctaaatcagcaccagcagctagca	CRISPR spacer
gcagctaaagcagcaccagcaaacactg	Protospacer
********* ***********. .* ..

24. spacer 1.1|193697|34|NZ_CP048387|PILER-CR matches to NC_014824 (Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence) position: , mismatch: 8, identity: 0.765

taacagatatgagttctatgttttattgagctac	CRISPR spacer
ttacagatatgagttatatgtttaattggtgcat	Protospacer
* ************* ******* ****.  .*.

25. spacer 1.4|193927|34|NZ_CP048387|PILER-CR matches to MK288021 (Bacillus phage pW2, complete genome) position: , mismatch: 8, identity: 0.765

caacatatatgagttatatgttttatgg-agccac	CRISPR spacer
ataattataagagttatctgttttatggaagtca-	Protospacer
  *  **** ******* ********** **.**

26. spacer 3.3|324993|31|NZ_CP048387|CRT matches to AJ972879 (Yersinia phage phiR1-37 complete genome) position: , mismatch: 8, identity: 0.742

taaaatgaattatgtattctataggactcaa	CRISPR spacer
cgaaatgaattaggtattctatatgagaata	Protospacer
..********** ********** **    *

27. spacer 3.3|324993|31|NZ_CP048387|CRT matches to NC_016163 (Yersinia phage phiR1-37, complete genome) position: , mismatch: 8, identity: 0.742

taaaatgaattatgtattctataggactcaa	CRISPR spacer
cgaaatgaattaggtattctatatgagaata	Protospacer
..********** ********** **    *

28. spacer 3.5|325140|34|NZ_CP048387|CRT matches to NZ_CP038863 (Campylobacter jejuni strain SCJK2 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.765

caatatggaagctatgttttattatgcagaatca	CRISPR spacer
gaatatggaagctatgtttcataatgcagttgag	Protospacer
 ******************.** ******    .

29. spacer 1.4|193927|34|NZ_CP048387|PILER-CR matches to NC_014824 (Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence) position: , mismatch: 9, identity: 0.735

caacatatatgagttatatgttttatggagccac	CRISPR spacer
ttacagatatgagttatatgtttaattggtgcat	Protospacer
. *** ***************** ** *.  **.

30. spacer 3.8|325140|39|NZ_CP048387|CRISPRCasFinder matches to NZ_CP038863 (Campylobacter jejuni strain SCJK2 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.769

caatatggaagctatgttttattatgcagaatcatttga	CRISPR spacer
gaatatggaagctatgtttcataatgcagttgagtttaa	Protospacer
 ******************.** ******    .***.*

31. spacer 1.4|193927|34|NZ_CP048387|PILER-CR matches to NZ_CP030933 (Enterococcus gilvus strain CR1 plasmid pCR1A, complete sequence) position: , mismatch: 10, identity: 0.706

caacatatatgagttatatgttttatggagccac	CRISPR spacer
tgacaaatatgagatatatgttttatagctgtag	Protospacer
..*** ******* ************.*   .*

32. spacer 1.4|193927|34|NZ_CP048387|PILER-CR matches to NC_014824 (Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence) position: , mismatch: 10, identity: 0.706

caacatatatgagttatatgttttatggagccac	CRISPR spacer
tcacagatatgagctatatgttttattggtgtaa	Protospacer
. *** *******.************ *.  .*

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage