CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP048622	Providencia stuartii strain MF1 plasmid pMF1A, complete sequence	0 crisprs	NA	0	0	0	0
NZ_CP048621	Providencia stuartii strain MF1 chromosome, complete genome	7 crisprs	WYL,DEDDh,csa3,cas3,cas14j,DinG,cas6f,cas7f,cas5f,cas8f,cas3-cas2,cas1,RT,c2c9_V-U4	0	16	13	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP048621_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP048621_1

1397514-1398081

Orphan

I-F

Consensus_repeat	Method
GTGTACTGCCGTATAGGCAGCTTAGAAA	PILER-CR
GTGTACTGCCGTATAGGCAGCTTAGAAA	CRISPRCasFinder
GTGTACTGCCGTATAGGCAGCTTAGAAA	CRT

9 spacers

csa3

The CRISPR arrays of NZ_CP048621_1

>merge|NZ_CP048621|1|1397514-1398081|PILER-CR,CRISPRCasFinder,CRT
GTGTACTGCCGTATAGGCAGCTTAGAAAATATGCGCATCCCAAGCTTCTGGGGGGCATGTGTGTACTGCCGTATAGGCAGCTTAGAAAGCGTTTAGGCAGCATCATTTTGCCGTCAGCATGTGTACTGCCGTATAGGCAGCTTAGAAACATCGATTTAAGATATCGCTGAACTGCACATTGTGTACTGCCGTATAGGCAGCTTAGAAATGATGATAACGGGCGCGATAAGCTAAATGAAAGTGTACTGCCGTATAGACAGCTTAGAAAAATATCCCAATCAACCAGCGGAAACACTTGTAGTGTACTGCCGTATAGGCAGCTTAGAAATTTATATGCATGTATTAAAGACAATCATGAAGGTGTACTGCCGTATAGGCAGCTTAGAAAGAGCTTCAAATGCCGCATTTAATCCGCCTAACGTGTACTGCCGTATAGGCAGCTTAGAAAATTAAGGGCGAGGTTAGAGTGAGAGCGAAAAGGTGTACTGCCGTATAGGCAGCTTAGAAAAAATGGTAAAGCGGTTGCATCTTTTAGTTTACGTGTACTGCCGTATAGGCAGCCTAAAAA

>NZ_CP048621|1|1|1397514-1398081|PILER-CR
GTGTACTGCCGTATAGGCAGCTTAGAAA	ATATGCGCATCCCAAGCTTCTGGGGGGCATGT
GTGTACTGCCGTATAGGCAGCTTAGAAA	GCGTTTAGGCAGCATCATTTTGCCGTCAGCAT
GTGTACTGCCGTATAGGCAGCTTAGAAA	CATCGATTTAAGATATCGCTGAACTGCACATT
GTGTACTGCCGTATAGGCAGCTTAGAAA	TGATGATAACGGGCGCGATAAGCTAAATGAAA
GTGTACTGCCGTATAGACAGCTTAGAAA	AATATCCCAATCAACCAGCGGAAACACTTGTA
GTGTACTGCCGTATAGGCAGCTTAGAAA	TTTATATGCATGTATTAAAGACAATCATGAAG
GTGTACTGCCGTATAGGCAGCTTAGAAA	GAGCTTCAAATGCCGCATTTAATCCGCCTAAC
GTGTACTGCCGTATAGGCAGCTTAGAAA	ATTAAGGGCGAGGTTAGAGTGAGAGCGAAAAG
GTGTACTGCCGTATAGGCAGCTTAGAAA	AAATGGTAAAGCGGTTGCATCTTTTAGTTTAC
GTGTACTGCCGTATAGGCAGCCTAAAAA

>NZ_CP048621|1|1|1397514-1398081|CRISPRCasFinder
GTGTACTGCCGTATAGGCAGCTTAGAAA	ATATGCGCATCCCAAGCTTCTGGGGGGCATGT
GTGTACTGCCGTATAGGCAGCTTAGAAA	GCGTTTAGGCAGCATCATTTTGCCGTCAGCAT
GTGTACTGCCGTATAGGCAGCTTAGAAA	CATCGATTTAAGATATCGCTGAACTGCACATT
GTGTACTGCCGTATAGGCAGCTTAGAAA	TGATGATAACGGGCGCGATAAGCTAAATGAAA
GTGTACTGCCGTATAGACAGCTTAGAAA	AATATCCCAATCAACCAGCGGAAACACTTGTA
GTGTACTGCCGTATAGGCAGCTTAGAAA	TTTATATGCATGTATTAAAGACAATCATGAAG
GTGTACTGCCGTATAGGCAGCTTAGAAA	GAGCTTCAAATGCCGCATTTAATCCGCCTAAC
GTGTACTGCCGTATAGGCAGCTTAGAAA	ATTAAGGGCGAGGTTAGAGTGAGAGCGAAAAG
GTGTACTGCCGTATAGGCAGCTTAGAAA	AAATGGTAAAGCGGTTGCATCTTTTAGTTTAC
GTGTACTGCCGTATAGGCAGCCTAAAAA

>NZ_CP048621|1|1|1397514-1398081|CRT
GTGTACTGCCGTATAGGCAGCTTAGAAA	ATATGCGCATCCCAAGCTTCTGGGGGGCATGT
GTGTACTGCCGTATAGGCAGCTTAGAAA	GCGTTTAGGCAGCATCATTTTGCCGTCAGCAT
GTGTACTGCCGTATAGGCAGCTTAGAAA	CATCGATTTAAGATATCGCTGAACTGCACATT
GTGTACTGCCGTATAGGCAGCTTAGAAA	TGATGATAACGGGCGCGATAAGCTAAATGAAA
GTGTACTGCCGTATAGACAGCTTAGAAA	AATATCCCAATCAACCAGCGGAAACACTTGTA
GTGTACTGCCGTATAGGCAGCTTAGAAA	TTTATATGCATGTATTAAAGACAATCATGAAG
GTGTACTGCCGTATAGGCAGCTTAGAAA	GAGCTTCAAATGCCGCATTTAATCCGCCTAAC
GTGTACTGCCGTATAGGCAGCTTAGAAA	ATTAAGGGCGAGGTTAGAGTGAGAGCGAAAAG
GTGTACTGCCGTATAGGCAGCTTAGAAA	AAATGGTAAAGCGGTTGCATCTTTTAGTTTAC
GTGTACTGCCGTATAGGCAGCCTAAAAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP048621.1\|WP_113742863.1\|1395752_1395869_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|288524
NZ_CP048621.1\|WP_004922295.1\|1393999_1395289_+\|arsenic-transporter	unknown	unknown	gnl\|CDD\|185342
NZ_CP048621.1\|WP_004922316.1\|1388117_1389260_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048621.1\|WP_004922284.1\|1398582_1398903_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048621.1\|WP_104872884.1\|1406997_1408428_+\|6-phospho-beta-glucosidase	unknown	unknown	gnl\|CDD\|182112
NZ_CP048621.1\|WP_004922304.1\|1391430_1391766_+\|metalloregulator-ArsR/SmtB-family-transcription-factor	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|236654
NZ_CP048621.1\|WP_104872882.1\|1410960_1412841_-\|heme-lyase-CcmF/NrfE-family-subunit	unknown	unknown	gnl\|CDD\|236675
NZ_CP048621.1\|WP_004922301.1\|1391813_1392179_+\|arsenite-efflux-transporter-metallochaperone-ArsD	unknown	unknown	gnl\|CDD\|377741
NZ_CP048621.1\|WP_004922269.1\|1403253_1404669_+\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223737
NZ_CP048621.1\|WP_104873612.1\|1400272_1400605_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048621.1\|WP_104872885.1\|1396127_1397308_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP048621.1\|WP_104872883.1\|1409870_1410968_-\|heme-lyase-NrfEFG-subunit-NrfF	unknown	unknown	gnl\|CDD\|182415
NZ_CP048621.1\|WP_004922246.1\|1409218_1409635_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048621.1\|WP_004922311.1\|1389954_1390812_-\|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase-FolD	unknown	unknown	gnl\|CDD\|236760
NZ_CP048621.1\|WP_042116859.1\|1392192_1393944_+\|arsenical-pump-driving-ATPase	unknown	unknown	gnl\|CDD\|275109
NZ_CP048621.1\|WP_004922288.1\|1398234_1398582_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048621.1\|WP_036941256.1\|1399180_1400104_+\|LpxL/LpxP-family-Kdo(2)-lipid-IV(A)-lauroyl/palmitoleoyl-acyltransferase	unknown	unknown	gnl\|CDD\|181200
NZ_CP048621.1\|WP_014656465.1\|1401622_1402195_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048621.1\|WP_014656527.1\|1389724_1389937_-\|ribosome-associated-protein-YbcJ	unknown	unknown	gnl\|CDD\|183166
NZ_CP048621.1\|WP_014656469.1\|1395299_1395725_+\|glutaredoxin-dependent-arsenate-reductase	unknown	unknown	gnl\|CDD\|182200

Protein	Function_ID	Function_description	E-value
NZ_CP048621.1\|WP_113742863.1\|1395752_1395869_-\|hypothetical-protein	gnl\|CDD\|288524	pfam11682, zinc_ribbon_11, Probable zinc-ribbon. This family of proteins with unknown function appears to be restricted to Enterobacteriaceae. It is a probably zinc-ribbon.	0.00972157
NZ_CP048621.1\|WP_004922295.1\|1393999_1395289_+\|arsenic-transporter	gnl\|CDD\|185342	PRK15445, PRK15445, arsenical efflux pump membrane protein ArsB.	0
NZ_CP048621.1\|WP_104872882.1\|1410960_1412841_-\|heme-lyase-CcmF/NrfE-family-subunit	gnl\|CDD\|236675	PRK10369, PRK10369, heme lyase subunit NrfE; Provisional.	0
NZ_CP048621.1\|WP_004922304.1\|1391430_1391766_+\|metalloregulator-ArsR/SmtB-family-transcription-factor	gnl\|CDD\|236654	PRK10141, PRK10141, DNA-binding transcriptional repressor ArsR; Provisional.	2.98221e-44
NZ_CP048621.1\|WP_004922301.1\|1391813_1392179_+\|arsenite-efflux-transporter-metallochaperone-ArsD	gnl\|CDD\|377741	pfam06953, ArsD, Arsenical resistance operon trans-acting repressor ArsD. This family consists of several bacterial arsenical resistance operon trans-acting repressor ArsD proteins. ArsD is a trans-acting repressor of the arsRDABC operon that confers resistance to arsenicals and antimonials in Escherichia coli. It possesses two-pairs of vicinal cysteine residues, Cys(12)-Cys(13) and Cys(112)-Cys(113), that potentially form separate binding sites for the metalloids that trigger dissociation of ArsD from the operon. However, as a homodimer it has four vicinal cysteine pairs.	7.15471e-61
NZ_CP048621.1\|WP_042116859.1\|1392192_1393944_+\|arsenical-pump-driving-ATPase	gnl\|CDD\|275109	TIGR04291, Arsenical_pump-driving_ATPase, arsenical pump-driving ATPase. The broader family (TIGR00345) to which the current family belongs consists of transport-energizing ATPases, including to TRC40/GET3 family involved in post-translational insertion of protein C-terminal transmembrane anchors into membranes from the cyotosolic face. This family, however, is restricted to ATPases that energize pumps that export arsenite (or antimonite).	0
NZ_CP048621.1\|WP_104872885.1\|1396127_1397308_+\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	3.97339e-106
NZ_CP048621.1\|WP_104872883.1\|1409870_1410968_-\|heme-lyase-NrfEFG-subunit-NrfF	gnl\|CDD\|182415	PRK10370, PRK10370, formate-dependent nitrite reductase complex subunit NrfG; Provisional.	9.8916e-78
NZ_CP048621.1\|WP_004922311.1\|1389954_1390812_-\|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase-FolD	gnl\|CDD\|236760	PRK10792, PRK10792, bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD.	0
NZ_CP048621.1\|WP_004922269.1\|1403253_1404669_+\|FAD-binding-oxidoreductase	gnl\|CDD\|223737	COG0665, DadA, Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism].	4.62431e-43
NZ_CP048621.1\|WP_104872884.1\|1406997_1408428_+\|6-phospho-beta-glucosidase	gnl\|CDD\|182112	PRK09852, PRK09852, cryptic 6-phospho-beta-glucosidase; Provisional.	0
NZ_CP048621.1\|WP_036941256.1\|1399180_1400104_+\|LpxL/LpxP-family-Kdo(2)-lipid-IV(A)-lauroyl/palmitoleoyl-acyltransferase	gnl\|CDD\|181200	PRK08025, PRK08025, kdo(2)-lipid IV(A) palmitoleoyltransferase.	7.84003e-165
NZ_CP048621.1\|WP_014656527.1\|1389724_1389937_-\|ribosome-associated-protein-YbcJ	gnl\|CDD\|183166	PRK11507, PRK11507, ribosome-associated protein YbcJ.	5.318e-32
NZ_CP048621.1\|WP_014656469.1\|1395299_1395725_+\|glutaredoxin-dependent-arsenate-reductase	gnl\|CDD\|182200	PRK10026, PRK10026, arsenate reductase (glutaredoxin).	1.56402e-86

>NZ_CP048621.1|WP_104872885.1|1396127_1397308_+|IS3-family-transposase
MAKRIRRLFSAEFKLEAAQLVLDQSYSVVEAANAMGVGKSTMDKWVRQLKLERKGISPKASPMTPEQVEIRELKKKIARLEEHNENLKKGYSAGDVGLSEQFSLIEKLSRRFSIKQLCNVFSVHRSSYQYWRHRSKIPSVEQTRLRALVREAHESSHGSAGARTIADIVSNTKQVPLTRYRASKLMKLLGLVSCQTSKHRYKKTTQEHVEIPNHLRRQFAVTEPNQVWVGDVTYIWSGNRWMYLAVVMDLFARKPIGWAMSFSPDSQLTGKALSMAFESRGKPRNILFHSDQGSHYTSRQYRQLLWRYQIKQSLSRRGNCWDNAPMERFFRSLKTEWVPILGYRNSIEAQQEITRYIIGYYSQLRPHQYNGGLTPNESERLYWENSKTVTNFC
>NZ_CP048621.1|WP_113742863.1|1395752_1395869_-|hypothetical-protein
MDWFCVPCHDDFTNNQKYCPTCHKGIWSIPTKNVADKH
>NZ_CP048621.1|WP_014656469.1|1395299_1395725_+|glutaredoxin-dependent-arsenate-reductase
MNEITIYHNPNCGTSRNTLAMIRNSGIEPAIIHYLETPPSRDVLVKLIADMKITVRALLRKNVEPYEQLNLEQDSYTDDQLIDFMLQYPILINRPIVVTPLGVKLCRPSEVVLDILPNQQQNEFIKEDGEVVVDKQGCRIK
>NZ_CP048621.1|WP_004922295.1|1393999_1395289_+|arsenic-transporter
MFIAALIFVLTITFVIWQPKGLGIGWSATVGAVLALIFGVISFQDIPIVWNIVWNATATFVAVIIISLLLDESGFFEWAALHVAKWGGGKGRLLFSYIVLLGATVAALFANDGAALILTPIVIAMLLALGFNKGTTLAFVMAAGFIADTASLPLIVSNLVNIVSADFFNIGFTEYASIMVPVDIAAIIATLVMLHWFFRKDIPKQYDMTKLSEPALAIKDMTTFKAGWLVLVLLLIGFFVLEPLGIPVSAIAAIGALILWVIAARGHTINTKKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTDYLSETLNYLADKGLWVATLGTGFITAFLSSIMNNMPTVLIGALSIEGSEASGVIQQAMVYANVIGADLGPKITPIGSLATLLWLHVLSQKNMTITWGYYFKTGIIMTIPVLIVTLVALVLRLSLLN
>NZ_CP048621.1|WP_042116859.1|1392192_1393944_+|arsenical-pump-driving-ATPase
MNFLDSTPNYLFFTGKGGVGKTSISCATAIKLAEEGKKVLLVSTDPASNVGQVFSQSIGNNIQPITLVPNLFAIEIDPQAAAEEYRNKIINPIKESLPEAVIQSITEQLSGACTTEIAAFDEFTGLLTNTEITRQFDHIIFDTAPTGHTIRLLQLPSAWSDFISDNPDGATCLGPMSGLEKQREQYSMAVQALSDNSLTRLVLVARPQSAALREVARTYSELSSLGIKNQQLIINGVFPETAMTENDKLSHALYSREQAALKSLPEALRSLPIDILYLQNINMVGVDALKQLLSNDMPQFSTITPTKQPISLPSLSELVGEISQQQHGLIMLMGKGGVGKTTIAASIAVKLAEKGLDVHLTTSDPAAHVESTLDGVLPNLQVSRIDPIAETERYRNYVLETKGKDLDAEGRALLEEDLRSPCTEEIAVFQAFSRIIRDAGKRFVVMDTAPTGHTLLLLDATGAYHKEIAKKMGKKGHFLTPMMQLQDPERTKVIITTLAETTPVLEAENLQNDLIRADIHPWAWVINNSLSITETTSPLLLSRAEQEVVQIEKVASTLAKRVAIVPLLETEPVGISALSQLAE
>NZ_CP048621.1|WP_004922301.1|1391813_1392179_+|arsenite-efflux-transporter-metallochaperone-ArsD
MKKLEVFDPALCCSTGVCGTEVDQALVDFATDADWLKKQGANVKRFNLAQEPMAFVNNIKVKTFLETAGAESLPLFILDGEIVLTGRYPKRHELARWFGIRLNIEKVETVKSCCGNDKTCC
>NZ_CP048621.1|WP_004922304.1|1391430_1391766_+|metalloregulator-ArsR/SmtB-family-transcription-factor
MEPLQLFKILGDQTRLDIVLLLKASGELCVCDIYTALNLSQPKTSRHLAMLREAGLLLDSKHGKWVHYRLSPALLPWVKSIIDVTYATEKNRVADLLKSLEKKESANRCSI
>NZ_CP048621.1|WP_004922311.1|1389954_1390812_-|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase-FolD
MLAKIIDGKTIAQTIRQEVAQKVQQRIEQGKRAPGLAVILVGANPASQIYVGSKRRACEEVGFLSRSYDLPDTTTEAELLKLIDDLNQDTEIDGILVQLPLPAGIDNVKVIERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLDRYGINTYGLNAVIIGASNIVGRPMSLELLLAGCTTTVTHRFTKDLEQHVRNADLLVVAVGKPNFIPGEWVKPGAIVIDVGINRLENGKVTGDVDFDEASKYASWITPVPGGVGPMTVATLIQNTLQACEEYHDI
>NZ_CP048621.1|WP_014656527.1|1389724_1389937_-|ribosome-associated-protein-YbcJ
MDIFRLEGHPHIELCDLLKIEGWAESGAMAKAMIAEGLVQVDGVIETRKRCKIAAGKVVSMGDQKIKVQD
>NZ_CP048621.1|WP_004922316.1|1388117_1389260_+|hypothetical-protein
MKYYYFKYKTMMSSVFNKYMTSTVIAFGFIHPVALAANFNAMPGQEIISLGNVNAEITLTKISAVNSSSAIRADGFGINTSSSKVDCLPSSYEMTVGKMKGYRVDQDIIIGFRSTNATGVASVGAGASTSGPFHDVTVKGAWDNYGNYTPSPVQNASTMWCGSAWPEATQHQWNTNRKNNKASIRGELFLYVGNNAKPGSYTLPSLYLIKSASSGDLVSHLIFPSGTVTVSYPPCSISTPTEVSFDTRKGLPVINPTSSISVNCGANDGRAFQIAISGQPVAPSTAVGNHAISLHYSDGTIGGLVRGYIGSNAAADAVGCVDRTSSIPFSVNNQGLNFMQIGAQTASSSQSQPLVWSLCPNKTEKPGKATGAAQLDIIFK
>NZ_CP048621.1|WP_004922288.1|1398234_1398582_+|hypothetical-protein
MKLLNKTIYTLIVAFISTAAMAEECIGDSTYQACTRSSTNAQGDNIIESYDTEGNSYSITSGSRDYADGSSEVFSVDSEGNEYSIKSWCDSSGCHTSDSEGNTCTITNTGEMIGC
>NZ_CP048621.1|WP_004922284.1|1398582_1398903_+|hypothetical-protein
MIKKILIIFIVLISAISVFAYNKLTIFTVQPIGAIPDGVTVVMWKKGDMRFFESPDGLCMQRVGKVNLLCRMTMLGSAIDKDNIIIRLPYSEYAYLKSTNGRKFDR
>NZ_CP048621.1|WP_036941256.1|1399180_1400104_+|LpxL/LpxP-family-Kdo(2)-lipid-IV(A)-lauroyl/palmitoleoyl-acyltransferase
MYANNLFSLKLLHPKYATTWLGIVILFLLVQLPYKWLVRLGAFLGVNSKYFIKRRVSIIKRNLELCFPNKNRKEIDDLVIENLRSLGIALFETGIAWFWSDKRIKKLFQVKGISNYQEAIAKNKGVIIVGVHFMSLELGGRIMGLCFPVNAMYRPHNNKAMEYIQTKGRCRSGKGMIDRKNLRFMVQELKSGKAIWFAPDQDFGRKGTVFAPFFSVKNTSTSKGTSTLAQLSHSPTLTVTLLRNRNGISYDLVLGKEIVNYPTSDALHDAATINSVLEKEIMKAPEQYLWAHRRFKTRPDGEPSLYI
>NZ_CP048621.1|WP_104873612.1|1400272_1400605_-|hypothetical-protein
MGVSIYYSATKKTHFNFEEKNTFETMVNQLNQAFPYKEDAETLYFYEEPSDQFLLQGSTKLPLDDESILLESIDYWLDCLSQLTLAFSTAQWSVSIEDSEATWVDDHWEM
>NZ_CP048621.1|WP_014656465.1|1401622_1402195_+|hypothetical-protein
MKKHILSITVLSAATLLVTGCSSNNDMWGEFANILSDANPVVQESEEWEAYSIKTTQQGVTYASASSADQQFVSKKMDAEYADALYRVSSPFARSDKTKEQLAKDNQGYRFKYNEIMVVKDKKTANTIGYCVNYDSDQIENGQVKPVKEKDKIRNHFIYVDKVKPLSVMTVGSDFTKVMCGEEFYNKYKK
>NZ_CP048621.1|WP_004922269.1|1403253_1404669_+|FAD-binding-oxidoreductase
MAITRRKFLIGGAVVAVAGGAGILTPMLTREGRFVPGTPRHGFVEGTAGPLPKQADVVVIGAGILGIMTAINLVERGLSVVIVEKGNIAGEQSSRFYGQVITYKMPDETFLLHHIGKQRWREMNAKVGVDTSYRTQGRVEVPLDEEDLDHVRKWIDTRSKNVGSDIPFKTRIIEGDELNQRLRGATSNWTIAGFEEDSGSLDAEIATFVMAEYAKKIGVKIYTNCAARGLETQAGAISDVVTEKGAIKTSRVVVAGGVWSRLFMQNLNVDVPTLPAYQSQQLISGSPTAPGGNVALPGNIFFREQADGTYATSPRVIVAPVVKESFIYGYKYLPLLSMPDFPVHISLNEQLINSFTQPTHWELDEVSPFEKNRNMTALPDIPELNSSLEKLKAEFPAFKDSKLIDQWSGAMAIAPDENPIISQVNEYPGLVINTATGWGMTESPVSSEITADLLLGKEPSLDVKPFSLYRF
>NZ_CP048621.1|WP_104872884.1|1406997_1408428_+|6-phospho-beta-glucosidase
MPGSLFPQDFLWGGAIAANQAEGACFEGGKGLSIADVIPYGANRHPVKMGIEKRFKLRDDEYYPSHLAIDFYHQYKRDIALMAEMGFSVFRTSIAWSRLFPRGDEVTPNPEGIAYYLDLFNECKKYHIEPLVTLCHFDVPMHLVTEYGSWRDRKMIDFFVTYAKACFEAFDGIVKYWLTFNEINLLLHTPFSSSGLVFEEGENSEQVKYQAAHHQLVASALATKIAHEVNAQNQVGCMLAGGGYYPWSPKPEDVWAAMEKDRENLFFIDVQVRGYYPAYAQRVFRENKVTLLVTEEDEQILKNTVDFVSFSYYASRCASADMGDGTNPSINAAQSLSSPYIKQSEWGWGIDPLGLRLTANMLYDRYQKPLFLVENGLGAHDKLNEDGEIIDDYRIDYHRSHIQALGDAIADGIPIMGYISWGCIDLVSASTGEMSKRYGFVYVDKDDQGAGSLTRIRKKSFWWYKKVIASHGNDLY
>NZ_CP048621.1|WP_004922246.1|1409218_1409635_-|hypothetical-protein
MKKNIFSYLIIALIAGGSFVAGMMANYTPDLDIVKKSQKAVEDFLTFPETAEYKNVHYYEIRQTLDHGILGYVCGEVLVFKSENSFGYKRFLVKTYMHQDGRNVVSIPLIERSGNIFPNDNFNIIWDQFCREQSDKKE
>NZ_CP048621.1|WP_104872883.1|1409870_1410968_-|heme-lyase-NrfEFG-subunit-NrfF
MNKLLHYVVLTLLLMATNIAKADIVDTWQFATAEQQTTSLQIAAQLRCPQCQNQNLLESNAPTAVSMRHQVYKMVAEGKTEAEIRSYMTERYGDFVLYNPPLHMGTIVLWSLPFIGFIFVIALLYYLIKKRASVPRTNQHNSTEATITPTSKLSIQLTHEIPSQHAEVKRNDTLSYYAIHLCVALLLLLTIAGYFFLPRFSVTYHEYQRISDPLHILTPLQQQQSDLIRLQNNIRQSPQNGDLWAILGEYYLYQNSYDNALIAYNQALKYTGENAQLYSAIATVLYYQAGQQMTEDTMQVIEHALSIDKHEVTALMLLASDAFMHANYEKAISLWQQLLDSNSPRINRSQLIEAINMATIMKNNH
>NZ_CP048621.1|WP_104872882.1|1410960_1412841_-|heme-lyase-CcmF/NrfE-family-subunit
MELILPEIGFISLLLTLCITNFHALFGLVSTYKHTQKSRLLGVYWSTLQFIFLVIAFLCLTISFIQSDFSVVYVAQHSHRLSPLLIKIAAVWGGHEGSLLLWVLLLSTWHLLFAWRYRKQDHPFFALTLAILAAMSAALLWFIVLYSDPFMRLFPPAIEGRDLNPMLQHWGLILHPPLLYLGYSGLMVVTSCVLASLIAGNFSQTIAWVCWRWAVPSWCILTMGITLGSWWAYSELGWGGWWFWDPVENASLLPWLAATALLHSLVASRKQGSYRHWSMILAIVTFILSLLGTLIVRSGILVSVHAFALDNVRAIPLFLLFISMSIVALLIYGCKAKPAVSASKRALTLREIYLQMTLILFVVVLFIVLVGTLYPMLYSLLGWGKISVGAPYFNQTLLPFGLIMLMVIGAWAVGSLKSSTRSFFRWRLSVSIIAAVIALLLRWSDAKFIASATAIMVGLLLLLWLRPLNEIQKRLASLLAHTGVIIFATGIAFSTVSKQEISANMTVNHTVSLAGYQFNFKQLQLDTQSNYTTEKALIAVYQKDTFITHLETERRFYTARQQIMIEPGMHWGWMRNWYAVLGEKTGNNRYALRFYVQDGIQWIWGGAFIMCIGLFIGWFKGRSQHE

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Crispr_ID: NZ_CP048621_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP048621_2

1788238-1788494

Orphan

Consensus_repeat	Method
CATACCAGATGGGTCGTTAGCTCAGTCGGTAGAGCAGTTGACTTTTAATCAAT	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP048621_2

>merge|NZ_CP048621|2|1788238-1788494|PILER-CR
AGATGGGTCGTTAGCTCAGTCGGTAGAGCAGTTGACTTTTAATCAATTGGTCGCAGGTTCGAATCCTGCACGACCCACCATCTTAATATTAAAATCAGTCATACCAGATGGGTCGTTAGCTCAGTCGGTAGAGCAGTTGACTTTTAATCAATTGGTCGCAGGTTCGAATCCTGCACGACCCACCATCTTAATATTAAAATCAGTCATACCAGATGGGTCGTTAGCTCAGTCGGTAGAGCAGTTGACTTTTAATCAAT

>NZ_CP048621|2|2|1788238-1788494|PILER-CR
AGATGGGTCGTTAGCTCAGTCGGTAGAGCAGTTGACTTTTAATCAATTGGTCGC	AGGTTCGAATCCTGCACGACCCACCATCTTAATATTAAAATCAGTCATACCA
GATGGGTCGTTAGCTCAGTCGGTAGAGCAGTTGACTTTTAATCAATTGGTCGCA	GGTTCGAATCCTGCACGACCCACCATCTTAATATTAAAATCAGTCATACCA
GATGGGTCGTTAGCTCAGTCGGTAGAGCAGTTGACTTTTAATCAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP048621.1\|WP_004921302.1\|1784125_1784542_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_CP048621.1\|WP_014656308.1\|1782645_1783830_+\|nucleoside-permease	unknown	unknown	gnl\|CDD\|224883
NZ_CP048621.1\|WP_163761981.1\|1776983_1777937_-\|cysteine-synthase-A	unknown	unknown	gnl\|CDD\|273465
NZ_CP048621.1\|WP_004921297.1\|1786024_1787446_-\|glutamate--tRNA-ligase	unknown	unknown	gnl\|CDD\|234953
NZ_CP048621.1\|WP_053110511.1\|1800526_1801321_+\|moaF	unknown	unknown	gnl\|CDD\|375179
NZ_CP048621.1\|WP_004921277.1\|1797719_1798607_+\|methionine-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270317
NZ_CP048621.1\|WP_004921311.1\|1779243_1780341_+\|cell-division-protein-ZipA	unknown	unknown	gnl\|CDD\|235124
NZ_CP048621.1\|WP_014656307.1\|1784674_1785427_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|235546
NZ_CP048621.1\|WP_004921318.1\|1776371_1776629_-\|phosphocarrier-protein-Hpr	unknown	unknown	gnl\|CDD\|182777
NZ_CP048621.1\|WP_004921272.1\|1799737_1800517_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|212491
NZ_CP048621.1\|WP_004921304.1\|1783899_1784115_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226061
NZ_CP048621.1\|WP_053110513.1\|1798815_1799553_+\|cyclase-family-protein	unknown	unknown	gnl\|CDD\|224790
NZ_CP048621.1\|WP_104873592.1\|1780398_1782414_+\|NAD-dependent-DNA-ligase-LigA	unknown	unknown	gnl\|CDD\|236137
NZ_CP048621.1\|WP_004921313.1\|1778214_1778979_-\|sulfate-transporter-CysZ	unknown	unknown	gnl\|CDD\|179898
NZ_CP048621.1\|WP_076914141.1\|1791061_1792789_-\|potassium/proton-antiporter	unknown	unknown	gnl\|CDD\|235410
NZ_CP048621.1\|WP_004921281.1\|1794957_1796418_-\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224983
NZ_CP048621.1\|WP_004921283.1\|1793940_1794954_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|236863
NZ_CP048621.1\|WP_061063873.1\|1796422_1797547_-\|peroxidase-related-enzyme	unknown	unknown	gnl\|CDD\|188545
NZ_CP048621.1\|WP_014656306.1\|1790400_1790694_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP048621.1\|WP_004921285.1\|1793275_1793944_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224922

Protein	Function_ID	Function_description	E-value
NZ_CP048621.1\|WP_004921302.1\|1784125_1784542_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	7.78713e-19
NZ_CP048621.1\|WP_014656308.1\|1782645_1783830_+\|nucleoside-permease	gnl\|CDD\|224883	COG1972, NupC, Nucleoside permease [Nucleotide transport and metabolism].	4.63903e-147
NZ_CP048621.1\|WP_163761981.1\|1776983_1777937_-\|cysteine-synthase-A	gnl\|CDD\|273465	TIGR01139, Cysteine_synthase, cysteine synthase A. This model distinguishes cysteine synthase A (CysK) from cysteine synthase B (CysM). CysM differs in having a broader specificity that also allows the use of thiosulfate to produce cysteine thiosulfonate. [Amino acid biosynthesis, Serine family].	4.46379e-176
NZ_CP048621.1\|WP_004921297.1\|1786024_1787446_-\|glutamate--tRNA-ligase	gnl\|CDD\|234953	PRK01406, gltX, glutamyl-tRNA synthetase; Reviewed.	0
NZ_CP048621.1\|WP_053110511.1\|1800526_1801321_+\|moaF	gnl\|CDD\|375179	pfam17409, MoaF_C, MoaF C-terminal domain. MoaF protein is essential for the production of the monoamine-inducible 30kDa protein in Klebsiella. It is necessary for reconstituting organoautotrophic growth in Ralstonia eutropha. It is conserved in Proteobacteria and some lower eukaryotes. The operon regulating the Moa genes is responsible for molybdenum cofactor biosynthesis. This entry corresponds to the C-terminal domain.	5.56296e-60
NZ_CP048621.1\|WP_004921277.1\|1797719_1798607_+\|methionine-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270317	cd13599, PBP2_lipoprotein_Gna1946, The membrane-associated lipoprotein Gna1946 from Neisseria meningitidis; the type 2 periplasmic binding protein fold. Gna1946 shares significant structural and sequence homology with the periplasmic substrate-binding domain of ATP-binding cassette (ABC) transporter involved in uptake of methionine (MetQ). The members of the MetQ-like family include the 32-kilodalton lipoprotein (Tp32) from Treponema pallidum, the membrane-associated lipoprotein-9 GmpC from Staphylococcus aureus, and Toll-like receptor 2-activating lipoprotein IlpA from Vibrio vulnificus. They all function as a receptor for methionine. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea.	9.16017e-78
NZ_CP048621.1\|WP_004921311.1\|1779243_1780341_+\|cell-division-protein-ZipA	gnl\|CDD\|235124	PRK03427, PRK03427, cell division protein ZipA; Provisional.	2.60072e-144
NZ_CP048621.1\|WP_014656307.1\|1784674_1785427_+\|SDR-family-oxidoreductase	gnl\|CDD\|235546	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG.	1.53534e-79
NZ_CP048621.1\|WP_004921318.1\|1776371_1776629_-\|phosphocarrier-protein-Hpr	gnl\|CDD\|182777	PRK10850, PRK10850, phosphocarrier protein Hpr.	3.87161e-44
NZ_CP048621.1\|WP_004921272.1\|1799737_1800517_+\|SDR-family-oxidoreductase	gnl\|CDD\|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	1.76199e-64
NZ_CP048621.1\|WP_004921304.1\|1783899_1784115_+\|hypothetical-protein	gnl\|CDD\|226061	COG3530, COG3530, Uncharacterized protein conserved in bacteria [Function unknown].	6.69466e-32
NZ_CP048621.1\|WP_053110513.1\|1798815_1799553_+\|cyclase-family-protein	gnl\|CDD\|224790	COG1878, COG1878, Kynurenine formamidase [Amino acid transport and metabolism].	5.41747e-52
NZ_CP048621.1\|WP_104873592.1\|1780398_1782414_+\|NAD-dependent-DNA-ligase-LigA	gnl\|CDD\|236137	PRK07956, ligA, NAD-dependent DNA ligase LigA; Validated.	0
NZ_CP048621.1\|WP_004921313.1\|1778214_1778979_-\|sulfate-transporter-CysZ	gnl\|CDD\|179898	PRK04949, PRK04949, putative sulfate transport protein CysZ; Validated.	1.75166e-146
NZ_CP048621.1\|WP_076914141.1\|1791061_1792789_-\|potassium/proton-antiporter	gnl\|CDD\|235410	PRK05326, PRK05326, potassium/proton antiporter.	0
NZ_CP048621.1\|WP_004921281.1\|1794957_1796418_-\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224983	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism].	1.18045e-36
NZ_CP048621.1\|WP_004921283.1\|1793940_1794954_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|236863	PRK11153, metN, DL-methionine transporter ATP-binding subunit; Provisional.	9.24724e-177
NZ_CP048621.1\|WP_061063873.1\|1796422_1797547_-\|peroxidase-related-enzyme	gnl\|CDD\|188545	TIGR04030, perox_Avi_7169, alkylhydroperoxidase domain protein, Avi_7169 family. Members of this family represent a narrow clade that falls within a family of alkylhydroperoxidase-related proteins, fused to or adjacent to a sequence described by TIGR04029. These two partners occur almost always in the context of a putative FMN-dependent luciferase-like monooxygenase (LLM) (TIGR04027), and an ABC transporter in which TIGR04028 models the substrate-binding protein.	4.12546e-68
NZ_CP048621.1\|WP_014656306.1\|1790400_1790694_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	9.95698e-12
NZ_CP048621.1\|WP_004921285.1\|1793275_1793944_-\|ABC-transporter-permease	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	5.53783e-89

>NZ_CP048621.1|WP_004921297.1|1786024_1787446_-|glutamate--tRNA-ligase
MSKIKTRFAPSPTGYLHVGGARTALYSWLFSRHNQGEFVLRIEDTDLERSTQEAIDAIMDGMNWLNLNWDEGPYYQTKRFDRYNDVIDQMLEAGTAYRCYCSKERLEALRDQQMASGEKPRYDGCCRDHAHNHTPDEPHVVRFRNPQEGSVIFDDKIRGPIEFSNQELDDLIIRRTDGSPTYNFCVVIDDWDMEITHVIRGEDHINNTPRQINILKALGAPVPEYAHVSMILGDDGKKLSKRHGAVSVMQYRDEGYLPEALLNYLVRLGWSHGDQEIFSREEMIEYFSLDAISKSASAFNTDKLLWLNHHYINQLPPEEVAVHLAWHIEQQNINTENGPQLAELVKLLGERCKTLKEIAESCRYFYEEFDEFDADAAKKHLRPVARQPLETVKQKLSAITDWTAENVHQAIEQTAAELDVGMGKVGMPLRVAVTGAGQSPALDVTVHAIGQTRAIARIDKALSFIAEREASAQ
>NZ_CP048621.1|WP_014656307.1|1784674_1785427_+|SDR-family-oxidoreductase
MQNLQEKVALVTGASTGVGEEIALHLYQCGATVFITGRNEISLQTAANKIDQSGERVIPLVMDVTSHEQFKAAITQIEQQCGALHYLVNNAGITGPHGVTIEDYPLADWDAVIATDVSGTFYGLKYGLPAIVRAGGGAVVNLSACNGVTGIAGISPYTAAKHAVLGLTRATALEYAQKGVRINAIGPGYVATPNIMNLPTETQEWMASTHPMGRMATREEIAKTVAFLLSDDSSFITGAFIPVDGGYTAQ
>NZ_CP048621.1|WP_004921302.1|1784125_1784542_-|MarR-family-transcriptional-regulator
MANQLEDALSLLQCTLVARRLSFTPEQVTWGQYDVLEILRLKGDQTPGQLSQLLGISRQNLSKFLRALKALGFVSQYQSEQDKRELITHLTDEGRDFLQRAATGRKENAAKVSSALTANEQALFIQLSQKVTAALGHD
>NZ_CP048621.1|WP_004921304.1|1783899_1784115_+|hypothetical-protein
MEKQDLIDMANTRMPFGKYQGRVLIDLPEEYLLWFYKKGAFPQGRLGQLMEMALGLKIEGLDGLVKPLKRV
>NZ_CP048621.1|WP_014656308.1|1782645_1783830_+|nucleoside-permease
MTSILHFVLSLVVIGALAVLASSNRKAIRLRYVFQLLVIQIALAYFFLNSNVGSSFVLGVASVFTHLLGYAAEGTKFVFGGMIEGNLAFFFLQVLCPIIFISALIGILQHIKVLPLVIRVIGTVLSKVNGMGKLESFNAVSSLLLGQSENFIAYKDQLGKMSERRMYTMAATAMSTVSMSIVGAYMSMLEPRFVVAALVLNMFGTFVILSLINPYPPEAEEELQMTNIHEGQSFFEMLGEYILAGFKVAIIVSAMLIGFIALIAMVNGICMAIFDIKFQTMLGYVFYPFAWILGIPAEEALQVGGIMAVKMVTNEFVAMGDLKEVAATLSTRSVGILSVFLVSFANFSSIGIVAGAIKGLNEKQGNTVARFGLKLLFGSTLVSFLSAAVVGLIL
>NZ_CP048621.1|WP_104873592.1|1780398_1782414_+|NAD-dependent-DNA-ligase-LigA
MTTKQHLDTLKQQLRHHEYQYHVLDAPEIPDAEYDKLMEELKAIEAEHPEWITSDSPTQRVGAAPLAAFDTVRHEIPMLSLDNVFDEESYLAFDKRMRDRLKDQQEQTFCCELKLDGLAVSLLYENGELVQAATRGDGTVGENITSNVRTIRAIPLRLTGENIPARVEIRGEVFMPQKGFEALNEEARRTGGKVFANPRNAAAGSLRQLDPRITAKRPLTFYCYGVGLVEGETLPDTHYERLMQFKKWGLPVSEYVQLRTGAQAVLDFYHEIEKARPTLGFDIDGVVIKINDIATQEELGFVSRAPRWATAFKFPAQEQMTLLKDVEFQVGRTGAITPVARLEPVQVAGVTVSNATLHNADEIERLGVHIGDTVVIRRAGDVIPQIVSVVESERPADSREIVFPTHCPVCGSDVERVEGEAVARCTGGLICGAQRKEALKHFVSRRAMDVDGMGDKIIDQLVEKEYVKNPADLYQLSAGILTGLDRMGPKSAQNLVEALNKSKSTTLARFIYALGIREVGEATAANLAAHYGTLEALMAADEESLKTVQDVGHVVAKHVVNFFREEHNQTVIQALIDKANIHWPEAVAVDVSTIDSPFAGKTVVLTGSLSQLTRDEAKDKLVALGAKVSGSVSKKTHLVIAGEAAGSKLAKANELGIPVIDENELIRLLEA
>NZ_CP048621.1|WP_004921311.1|1779243_1780341_+|cell-division-protein-ZipA
MRLGLQLKVFWLIFCRGGIIIQQLEIAAMQDLRLILVVVGAIAIIALLLHGLWTSRKERSKLFRDRPVKRRKHDSQDKSSDYDDDSALFSETQKVEPPVSSPVVSEPARQVQEERRAEPDLPPITSSTRDTEPVLNITPERSEPVESDIDSRVNAVNEQPAMKVEPTVQPIATPVSTANGRTQHAPEQPEFDFDIHEEQEGPQPTHHEQEQAHTEKKTEQPQNQSSENNKETVLVLHVAALQGQVLQGEALLQSILQAGFQFGEMRIFHRHVHPSGTGPVLFSLANMVKPGSFDPETMSEFTTPGISMFMMVPSYGEAGQNFKLMLQAAQRIASDVGGVVLDDERKMLTPQKIEVYHARIRNTLN
>NZ_CP048621.1|WP_004921313.1|1778214_1778979_-|sulfate-transporter-CysZ
MIQSTDSQQKSHSGFYYFVQGWRLVTRPGIKRFVILPLLANIILLGGAFWWLYTKLGGWIDQVMSYIPSWLQWLDYLIWPISVISILLIFTYFFSTVANIIAAPFNGWLSEKLESELTGVPAPDGGIVDIAKDVPRMVKREFVRIGYYLPRAIGLLILFFIPGIGQTVAPILWFLFGAWMMSIQYCDYPFDNHRVSFSEMKNALAKDRMNNIQFGGAVSVLMMIPILNLIIMPVAVCGATLMWVDQYRARHARY
>NZ_CP048621.1|WP_163761981.1|1776983_1777937_-|cysteine-synthase-A
MSKIYDDNSLTIGHTPLVRLKHFGNGNILAKVESRNPSFSVKCRIGANMIWDAEKKGLLTKEKELVEPTSGNTGIALAYVAAARGYKLTLTMPETMSVERRKLLKVLGANLVLTEGAKGMKGAIEKAEEIVNSNPHKYILLQQFNNPANPEIHEKTTGPEIWSDTDGKVDVVIAGVGTGGTITGIGRYLKKTKGKNVTLVAVEPETSPVISQTLAGDEVKPGPHKIQGIGAGFIPGNLDITLIDRVFKISDDEAIQTARQLMEKEGILAGISSGAALAAAVKLAAEPEFKDKNIVVILPSSGERYLSTVLFSDLSAE
>NZ_CP048621.1|WP_004921318.1|1776371_1776629_-|phosphocarrier-protein-Hpr
MFQQEVTITAPNGLHTRPAAQFVKEAKAFSSDITLTSGGKSASAKSLFKLQTLGLTQGTVVTISAEGEDEKQAVEHLVKLMGELE
>NZ_CP048621.1|WP_014656306.1|1790400_1790694_+|helix-turn-helix-transcriptional-regulator
MNTKYPVACAVGQKIKSLRKSQGYTVFQLAKEIDISEQQLFRYERGVNRIDIDCLVRVLKVLDVNMGEFFSEILQDDTHANEDKESKGFDDSIYSLI
>NZ_CP048621.1|WP_076914141.1|1791061_1792789_-|potassium/proton-antiporter
MPTIEQLILLTSILILLGIFSSKLSARLGLPMLVMFLFIGMLAGEDGIGQIAFNNVNVSYAVGSLALALILFDGGLQTSVKSIRLVWKPAFTLATFGVLITAGITGLAAAYILGIPLLEGLLLGAIVGSTDAAAVFSLLRNAGIYLNERLQSTLEIESATNDPMAIFLTVGLLQLLMNQSASGSELLLLFVSQMGIGTLVGLSVGWISIKIINKIKLLATGLYPVLVAACGLLSFGLASNLQGSGFLSIFVTGVVIGNARFVFQRNTFLFHDGLAWLSQIIMFVMLGLLVNPSSLLEVWFEGLVIALVLTFIARPIAVVPVLKFFKFSREEITLVSWVGLRGSVPIILAIFPFIYGLPGANLIFDVVFFVVLISATLQGSTLPYVARKLNLMQPPPLLPAATLDITAVDQIDADLVEYTLGEDCSAVGRRLSQLALPDQTVIAMITRGKSVLPPRGSTRLIADDHLFVVLKPENRLFLERLFSEQVSPDLTPIELPTSGLSLKGTTRLDEIYESYGILIDNENNQTLDQFIYSISANEPIQDTVISLATLQIRISEMIGSRIVTAVLEPLPQEDN
>NZ_CP048621.1|WP_004921285.1|1793275_1793944_-|ABC-transporter-permease
MTQWLDTALTSKQFLLAMSETFTMVSIALVIGSLLGILLGIALVVTRPDGIWENKWVYRIINPIINTVRSLPFIILLVAMIPLTRFMVGTSIGTTAAIVPLVIYIAPYTARLIENSLLSVHSGIIEAADSMGATNWQIVWHFILPEAKSSLILSLTAASITLVGATAMAGAVGGGGVGDLALNYGYQRFDNVAMAITVVTLVIIVQGIQMIGDYLAKKARFH
>NZ_CP048621.1|WP_004921283.1|1793940_1794954_-|ATP-binding-cassette-domain-containing-protein
MITFKNIQKVYEKEGHSLTALQDVNLQIHEGDIFGFIGYSGAGKSSLIRLVNQLEKPSSGEVIINGKNIAHHSATEIRAHKKSIGMIFQHFNLLETKTVAQNIAMPLLLSGVDKKEIQRRVDDILAYVELSDKKHQYPGQLSGGQKQRVGIARALINNPKILLCDEATSALDPQTTQSILSLLKKINREQNITILLVTHEMEVIEQICNRVAVMEAGRVVEEGTVLEIFSEPQHPTTKKFVRTVLNEEIPERVLHNLEHQSNVYRLEFLGASAQQPVVNELILQDKVKINILFANMKEISGVVLGSMFVQIVGHDEDIDQGIAFLRQRGVAVNKGVL
>NZ_CP048621.1|WP_004921281.1|1794957_1796418_-|NAD(P)/FAD-dependent-oxidoreductase
MTQLKGLNALEEQITQDLQNLNLPLNRWSLSPNQSDDHQLDVAIIGAGMSGVTAAFALKLQGIDAIVFDQAPEGQEGPWQTPALMETLRSPKQVVGPALASPSLTFQAWFKAQFGDDEWEALDKIPRLQWGEYLQWFKTMTSPVVFNQYQLTDIQVNPQGCLLTFATPNGKQQYQAQHVILATGMESFSEPNIPSFMAEIPSAYWEHSYAGSDYSRFKGLDIAVVGYSAGAMDSSATALEQGARSVELLIRAKDMPRVNRGKVAGNPGFTQAYHQLTDAQKWHYSDYVAKAKTPAPHGSTLRVSRHENAYFNFNTQVKKIDVNGKKLHIATTTGEYVVDYLILATGYRINWQRHSAFNHIAPFIRKWGDVYTPSKAEQNSEFASYPYLGHHFEFLPKTDCELPKLSNIYCFNLAASLSMGPLIGLIPNTNTGAQKLAEHIAAQLYLAHHEQHLEQVKNSTEAELLGDEWQPALPYSQRTPQTSNVE
>NZ_CP048621.1|WP_061063873.1|1796422_1797547_-|peroxidase-related-enzyme
MPILNYDLIDALINITPESTLADARKERSNATENTQAAFEAIFSAPSPQLTGEIKFLFARIIAEQTGSHVLADFYNQLLGQRSPHLNTPALQAAEHYLRILVSQPKQTHYSLIHALIEQGWHEADIILLAQLITFVTYQARLIEGLRLLQGNSTITKSAEPVTAGQWNSNSHTHQGQPAPTAFTQDQLGWESWLRARDPQTLEADEAQVMKKFGQLNSEYFLLLAHQSHILTLRTLIDRGVFYTLGGLPRWEREFAAAAVSKVNGCIYCASVHARKASQYAKEHKADVEKLIATPVGAILAEGFDDRLTAITDFTTALSTTPIRATHQQVETLRQLGLSELELLDLIQSTAFFSWANRLMLSLGEPFELKQDKE
>NZ_CP048621.1|WP_004921277.1|1797719_1798607_+|methionine-ABC-transporter-substrate-binding-protein
MIILATLFTQGRNIMLKQKIKYLSLIATAVIALAACNDNSEKDNPNKKEITIGFGVGNYIDQVEKGIVPILEKKGYKVNLRQFSQNRQINPAFEEGSIDASVNQSRAYMEAYNKKNNINMVALTDSPSAPQSLRSNKHKSLDEVKDGMIVALSNDPVNAERGARILEELGWIKIKPNISTLTFSVNDIEPAKYRLDIRETDAAQGLRLLDDVDFVVVNGNYVASAGQRIADGLVVENSPLEHRVIVTVMQDNVNSQWAKDLKEAFESKEYADYIRSQSIYDGFIEPQAWANYPKP
>NZ_CP048621.1|WP_053110513.1|1798815_1799553_+|cyclase-family-protein
MENDLITALKLLKSKTWVDLTHPFDKDSPHFFMFESASIKTLFDYPDGFFAQQFTFPGQYGTHIDAPCHFVEGKRYLHELELKELVLPLIVIDQSKRAKQDPTFAFSRQDVLNFEQEYGKIEPDTFVALRTDWSHRWPSQEAMDNKDAEGNNQIPGWGIDALKFLFEERGIKAIGHETFDTDAAQDFRRHNALLGEYYVLEQDTYQIELMTNLDKLPTRGAVIFNIVAKPNNASGFPVRSFAILP
>NZ_CP048621.1|WP_004921272.1|1799737_1800517_+|SDR-family-oxidoreductase
MNSRSVIITGGGTGIGAACAQLFTQQGDQVFIVGRRAEPLNAVALETGAIAIVADVSTETSWNEIILPQIKQHTSTIDVLVCNAGGMGLGRVEDMNDQQWHQAMKANLDSAFASVRGCIPLLTQSHGNVLFVGSLASLAAGPEACGYVTAKHALIGLMRSVARDYGHQGVRANAVCPGWVRTPMADEEMQPLMEQHQFTLDDAYRYVCRDVPLQRPATAKEVALACRFLCSTDASMITGAALVIDGGASVVDLPTLAFT
>NZ_CP048621.1|WP_053110511.1|1800526_1801321_+|moaF
MIEEVAFIQVGALSDGFAPDSYILETNNQLTGKTFQLRFAEKDRQEDISFPADQQIEWQGVTIDCRVTSIRSGVYFVNFISPDDWQASVTLIINEKDGNCVLVQGKLPDEADIRISAFSKVEQNRPLTDVEVEIYFGTLGEAQRSLPAYTSELIGMRNMYTYNPKERYEHVYLNEQFYAWHCLDGVEKGLADVDRCHYIKVSEQLYLFIWREKIIPTLGIILIDLDMMRTDGGIMGYQDQAFSAVSLFPVGAHATILNKTSYPK

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Crispr_ID: NZ_CP048621_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP048621_3

2823278-2823485

Orphan

I-F

Consensus_repeat	Method
GTTCACTGCCGTATAGGCAGCTTAGAAA	PILER-CR
TTTCTAAGCTGCCTATACGGCAGTGAAC	CRISPRCasFinder
TTTCTAAGCTGCCTATACGGCAGTGAAC	CRT

3 spacers

The CRISPR arrays of NZ_CP048621_3

>merge|NZ_CP048621|3|2823278-2823485|PILER-CR,CRISPRCasFinder,CRT
TTTTTAAGCTGCCTATACGGCAGTGAACGTCATCAAGCACCAGTAAATCAACCTCACACATTTCTAAGCTGCCTATACGGCAGTGAACAACTTGCTATCGAAGTCAGAGAGGGTAATGGCTTTCTAAGCTGCCTATACGGCAGTGAACTAATTGCGGTGCGCAATCAGCTCAAATGATTGTTTCTAAGCTGCCTATACGGCAGTGAAC

>NZ_CP048621|3|3|2823278-2823485|PILER-CR
TTTTTAAGCTGCCTATACGGCAGTGAAC	GTCATCAAGCACCAGTAAATCAACCTCACACA
TTTCTAAGCTGCCTATACGGCAGTGAAC	AACTTGCTATCGAAGTCAGAGAGGGTAATGGC
TTTCTAAGCTGCCTATACGGCAGTGAAC	TAATTGCGGTGCGCAATCAGCTCAAATGATTG
TTTCTAAGCTGCCTATACGGCAGTGAAC

>NZ_CP048621|3|2|2823278-2823485|CRISPRCasFinder
TTTTTAAGCTGCCTATACGGCAGTGAAC	GTCATCAAGCACCAGTAAATCAACCTCACACA
TTTCTAAGCTGCCTATACGGCAGTGAAC	AACTTGCTATCGAAGTCAGAGAGGGTAATGGC
TTTCTAAGCTGCCTATACGGCAGTGAAC	TAATTGCGGTGCGCAATCAGCTCAAATGATTG
TTTCTAAGCTGCCTATACGGCAGTGAAC

>NZ_CP048621|3|2|2823278-2823485|CRT
TTTTTAAGCTGCCTATACGGCAGTGAAC	GTCATCAAGCACCAGTAAATCAACCTCACACA
TTTCTAAGCTGCCTATACGGCAGTGAAC	AACTTGCTATCGAAGTCAGAGAGGGTAATGGC
TTTCTAAGCTGCCTATACGGCAGTGAAC	TAATTGCGGTGCGCAATCAGCTCAAATGATTG
TTTCTAAGCTGCCTATACGGCAGTGAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP048621.1\|WP_004918885.1\|2829969_2830464_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048621.1\|WP_104873407.1\|2809970_2811440_+\|aldehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|143432
NZ_CP048621.1\|WP_004918896.1\|2827992_2828220_+\|HEAT-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|379311
NZ_CP048621.1\|WP_104873405.1\|2815430_2818430_-\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|273807
NZ_CP048621.1\|WP_163762248.1\|2824431_2824974_+\|sulfatase-like-hydrolase/transferase	unknown	unknown	gnl\|CDD\|293741
NZ_CP048621.1\|WP_036943814.1\|2822084_2822450_+\|DUF305-domain-containing-protein	unknown	unknown	gnl\|CDD\|226074
NZ_CP048621.1\|WP_004918910.1\|2823947_2824244_-\|antibiotic-biosynthesis-monooxygenase	unknown	unknown	gnl\|CDD\|224278
NZ_CP048621.1\|WP_004918906.1\|2825310_2825475_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048621.1\|WP_014658149.1\|2831136_2831787_-\|DUF4431-domain-containing-protein	unknown	unknown	gnl\|CDD\|373092
NZ_CP048621.1\|WP_104873403.1\|2819975_2820740_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|366565
NZ_CP048621.1\|WP_104873408.1\|2809162_2809957_+\|aspartate-dehydrogenase	unknown	unknown	gnl\|CDD\|237342
NZ_CP048621.1\|WP_104873406.1\|2811508_2813152_+\|thiamine-pyrophosphate-binding-protein	unknown	unknown	gnl\|CDD\|180820
NZ_CP048621.1\|WP_004918937.1\|2814175_2814607_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048621.1\|WP_104873404.1\|2818447_2819908_-\|DUF560-domain-containing-protein	unknown	unknown	gnl\|CDD\|368004
NZ_CP048621.1\|WP_101495226.1\|2826120_2827229_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|372671
NZ_CP048621.1\|WP_014658148.1\|2832517_2833513_+\|chitinase	unknown	unknown	gnl\|CDD\|226000
NZ_CP048621.1\|WP_004918928.1\|2814626_2815382_-\|energy-transducer-TonB	unknown	unknown	gnl\|CDD\|223880
NZ_CP048621.1\|WP_053110723.1\|2828795_2829575_-\|elongation-factor-Tu	unknown	unknown	gnl\|CDD\|177010
NZ_CP048621.1\|WP_036943804.1\|2834299_2834902_-\|thiamine-biosynthesis-protein-ThiJ	unknown	unknown	gnl\|CDD\|153229
NZ_CP048621.1\|WP_036943812.1\|2822575_2823049_-\|membrane-protein	unknown	unknown	gnl\|CDD\|378715

Protein	Function_ID	Function_description	E-value
NZ_CP048621.1\|WP_104873407.1\|2809970_2811440_+\|aldehyde-dehydrogenase	gnl\|CDD\|143432	cd07114, ALDH_DhaS, Uncharacterized Candidatus pelagibacter aldehyde dehydrogenase, DhaS-like. Uncharacterized aldehyde dehydrogenase from Candidatus pelagibacter (DhaS) and other related sequences are present in this CD.	0
NZ_CP048621.1\|WP_004918896.1\|2827992_2828220_+\|HEAT-repeat-domain-containing-protein	gnl\|CDD\|379311	pfam13646, HEAT_2, HEAT repeats. This family includes multiple HEAT repeats.	5.29088e-06
NZ_CP048621.1\|WP_104873405.1\|2815430_2818430_-\|TonB-dependent-receptor	gnl\|CDD\|273807	TIGR01785, Heme/hemopexin_utilization_protein_C, TonB-dependent heme/hemoglobin receptor family protein. This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins].	1.13617e-18
NZ_CP048621.1\|WP_163762248.1\|2824431_2824974_+\|sulfatase-like-hydrolase/transferase	gnl\|CDD\|293741	cd16017, LptA, Lipooligosaccharide Phosphoethanolamine Transferase A (LptA) or Lipid A Phosphoethanolamine Transferase. Lipooligosaccharide Phosphoethanolamine Transferase A (LptA) or Lipid A Phosphoethanolamine Transferase catalyzes the modification of the lipid A headgroups by phosphoethanolamine (PEA) or 4-amino-arabinose residues. Lipopolysaccharides, also called endotoxins, protect bacterial pathogens from antimicrobial peptides and have roles in virulence. The PEA modified lipid A increases resistance to the cationic cyclic polypeptide antibiotic, polymyxin. Lipid A PEA transferases usually consist of a transmembrane domain anchoring the enzyme to the periplasmic face of the cytoplasmic membrane.	2.73448e-33
NZ_CP048621.1\|WP_036943814.1\|2822084_2822450_+\|DUF305-domain-containing-protein	gnl\|CDD\|226074	COG3544, COG3544, Uncharacterized protein conserved in bacteria [Function unknown].	3.11722e-22
NZ_CP048621.1\|WP_004918910.1\|2823947_2824244_-\|antibiotic-biosynthesis-monooxygenase	gnl\|CDD\|224278	COG1359, COG1359, Uncharacterized conserved protein [Function unknown].	4.55236e-22
NZ_CP048621.1\|WP_014658148.1\|2832517_2833513_+\|chitinase	gnl\|CDD\|226000	COG3469, COG3469, Chitinase [Carbohydrate transport and metabolism].	1.0477e-165
NZ_CP048621.1\|WP_014658149.1\|2831136_2831787_-\|DUF4431-domain-containing-protein	gnl\|CDD\|373092	pfam14485, DUF4431, Domain of unknown function (DUF4431).	3.0978e-14
NZ_CP048621.1\|WP_104873403.1\|2819975_2820740_-\|hypothetical-protein	gnl\|CDD\|366565	pfam01298, TbpB_B_D, C-lobe and N-lobe beta barrels of Tf-binding protein B. Bacterial lipoproteins represent a large group of specialized membrane proteins that perform a variety of functions including maintenance and stabilization of the cell envelope, protein targeting and transit to the outer membrane, membrane biogenesis, and cell adherence. Pathogenic Gram-negative bacteria within the Neisseriaceae and Pasteurellaceae families rely on a specialized uptake system, characterized by an essential surface receptor complex that acquires iron from host transferrin (Tf) and transports the iron across the outer membrane. They have an iron uptake system composed of surface exposed lipoprotein, Tf-binding protein B (TbpB), and an integral outer-membrane protein, Tf-binding protein A (TbpA), that together function to extract iron from the host iron binding glycoprotein (Tf). TbpB is a bilobed (N and C lobe) lipid-anchored protein with each lobe consisting of an eight-stranded beta barrel flanked by a handle domain made up of four (N lobe) or eight (C lobe) beta strands. TbpB extends from the outer membrane surface by virtue of an N-terminal peptide region that is anchored to the outer membrane by fatty acyl chains on the N-terminal cysteine and is involved in the initial capture of iron-loaded Tf. This domain family is found in C and N lobe eight stranded beta barrel region of TbpB proteins. The eight-stranded barrel domains in N and C lobe draw comparisons to eight-stranded beta barrel outer-membrane protein W (OmpW). However, the barrel domains of TbpB have the hydrophobic residues line the inner surface of the beta barrels to create a stable hydrophobic core.	2.04365e-05
NZ_CP048621.1\|WP_104873408.1\|2809162_2809957_+\|aspartate-dehydrogenase	gnl\|CDD\|237342	PRK13303, PRK13303, aspartate dehydrogenase.	2.48719e-109
NZ_CP048621.1\|WP_104873406.1\|2811508_2813152_+\|thiamine-pyrophosphate-binding-protein	gnl\|CDD\|180820	PRK07064, PRK07064, thiamine pyrophosphate-binding protein.	0
NZ_CP048621.1\|WP_053110723.1\|2828795_2829575_-\|elongation-factor-Tu	gnl\|CDD\|177010	CHL00071, tufA, elongation factor Tu.	4.04022e-08
NZ_CP048621.1\|WP_104873404.1\|2818447_2819908_-\|DUF560-domain-containing-protein	gnl\|CDD\|368004	pfam04575, DUF560, Protein of unknown function (DUF560). Family of hypothetical bacterial proteins.	1.77499e-38
NZ_CP048621.1\|WP_101495226.1\|2826120_2827229_-\|IS3-family-transposase	gnl\|CDD\|372671	pfam13683, rve_3, Integrase core domain.	2.75833e-25
NZ_CP048621.1\|WP_004918928.1\|2814626_2815382_-\|energy-transducer-TonB	gnl\|CDD\|223880	COG0810, TonB, Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane].	7.0707e-23
NZ_CP048621.1\|WP_036943804.1\|2834299_2834902_-\|thiamine-biosynthesis-protein-ThiJ	gnl\|CDD\|153229	cd03135, GATase1_DJ-1, Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1. Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1. DJ-1 is involved in multiple physiological processes including cancer, Parkinson's disease and male fertility. It is unclear how DJ-1 functions in these. DJ-1 has been shown to possess chaperone activity. DJ-1 is preferentially expressed in the testis and moderately in other tissues; it is induced together with genes involved in oxidative stress response. The Drosophila homologue (DJ-1A) plays an essential role in oxidative stress response and neuronal maintenance. Inhibition of DJ-1A function through RNAi, results in the cellular accumulation of reactive oxygen species, organismal hypersensitivity to oxidative stress, and dysfunction and degeneration of dopaminergic and photoreceptor neurons. DJ-1 has lacks enzymatic activity and the catalytic triad of typical GATase1 domains, however it does contain the highly conserved cysteine located at the nucelophile elbow region typical of these domains. This cysteine been proposed to be a site of regulation of DJ-1 activity by oxidation. DJ-1 is a dimeric enzyme.	1.73702e-16
NZ_CP048621.1\|WP_036943812.1\|2822575_2823049_-\|membrane-protein	gnl\|CDD\|378715	pfam11776, RcnB, Nickel/cobalt transporter regulator. RcnB is a family of Proteobacteria proteins. RcnB is required for maintaining metal ion homeostasis, in conjunction with the efflux pump RcnA, family NicO, pfam03824.	0.00396084

>NZ_CP048621.1|WP_036943812.1|2822575_2823049_-|membrane-protein
MNKLFRMCNLLLLTASFSMVSLSSYADPNGGHGHGQGKEHQKNKPNKGHNGNGKEKADHLSLNKSNSISVSLTYNEARALALDSGITGYHALPPGIAKNLARGKPLPPGIAKKVVPPSMLVQLPHYPGYEWSIVGNDLVLIALSTAVVTSIINNVFD
>NZ_CP048621.1|WP_036943814.1|2822084_2822450_+|DUF305-domain-containing-protein
MKKMLPIAAILTISIASFSSFANSNHSMHAQAPASNEMQKELNQSMDKMHADMAKSMNEENADIAFAQGMIAHHLGAIDMAKIELKYGTDPEMRKLAEEIINAQGPEIEQMQKWLEKNKTK
>NZ_CP048621.1|WP_104873403.1|2819975_2820740_-|hypothetical-protein
MARNIMKNLSLTALTIVLSSVAFSTSGETVSGQSQAYDSNGVEVNVGKTQFAQGTHSGVIGDPGVGLKTIANGTRIGFSGFKSLAPENEQGVNVLPASSGGHGGAMGEFHFTQVANAEVYFGDWSKTGSVGDQSHTAFFSGKEATESVPTAGQAEYTIAGINQFDGQGKLSGVFNADFGSKKYTGALNGQSLNITMNGNIQDKGQFSGSAIANGSIQGKSSGQFFGKNADVVAGITTFDSDHTKDTSFGGSKVQ
>NZ_CP048621.1|WP_104873404.1|2818447_2819908_-|DUF560-domain-containing-protein
MGLFRAGILWLLLYSSVAIGEISDIDNYRFLLKDKAEFSRKSPVIENNKPFIKDDIKINFDGKEYQVSNTLNEMGMAIYIALNRGQYDDVERLLSYYQQLSGYDVLLVEFAKAQMARANHDYAQAIFHYQTILALKPDFLRVELELARTYFEDQQNNEASSQFKRVLEKYQQQLPQSVLATISQFITELSKRNSWSGSFSVGYGYNSNINQVPGDKRQRCYRNAVQQFCYGAGLADKGTKFIYDGDIKRTFSLYQHHSLLFKAYTYGYKYDGAAEYNENTSHIRVYYQYQDAKKSFAIGPISEFKWVGERRHYYGVGVGMEAEYRFLPQFSLSTVIDHQKINYRSPYQSQDGNKSQAYITGIYALSSDAVIFGGVDSGYVNKVYDSDSYKQYGIRGGIFKDVSQYYHLLGIASYKQTRFNAPQYALGSQNRMDDEQLYLAKLSLPKYSIATMTPSISYRYRVNKSNIDALYSYQQSEIEIRLEKRF
>NZ_CP048621.1|WP_104873405.1|2815430_2818430_-|TonB-dependent-receptor
MKIKKIITMNIVTGISLTLISGLVLAKEQEDLGTIIVKDNAETIKERDQKGYDDQYDKNESNIYLGKDLVERYKGTNPADVLNSAVGVYSGDARNSGALDPNIRGIQGQGRVPVTVDGTEQAQTVWRGYNGANNRNYVDPNMISSITIQKSASLNPNVKTSVGGGIAIKTLNIDDVVAPDETFGFDLKLETSSNSTKPRVPNLGYGHDYRDDPAIMDNIKNGNKARMLFNDPGLLVTPKSRGDANFFNFKDNAVRVAVGTRQSRFDIMAAYSYRDQGNYFAGKRGANRYKDDVFSYDPKNPSKPVDPYLPFAANVFAPGKEVTNTSSEMESYLVKTNLFLSDSQKVSLGYTHTTNHYGEIMPSRISFMELDGKVPQWTLAKFNIQAFHADYYLNPEDNPYVNMKLGYWMTKTTSDTNTSGGFPREPKERDMGFEYGWMPRNPNIDGTLVPGASLNSTNKRQGLNLSNQMALTDSLDLTLMGSFSKETVDTEDDIFEYSGSSTSTIFRAVPREGERQENTFAFNFEWRPTDWLNVTAGAQRTSYWSKDHLLDKRRDAKDVNFARPHQLLSKNYDISRTITQNEYDTLTRFTNAEGQKLDDVMDSPYYLERFVEEALNLQKHSLDYAGFRSANGQGEFRIDEKNKAKWRPDGKNKLTRETNPFYNGTIDTKAQTVDPFTGKVVNQYIPNQSRSSDEQEDIRYLSEEERFRHQGKKKAHAWAPSFSASAYLTDNDRVYASYTETVRMPSIFEDTVGFSGSRGYASLTEKFEPERGKTVEVGYVRNLQSLLGAERFADVRINYYHTVIENAFERDIYLKFTQVDKHKTSGIELQARYDNGNYFGDIGLDYRLQNEVCDSASIAALDPTNKFNMSECVDAGFPGGFLRTQLQPKYSINANLGMRFLDERLEIGSRMRYHSRAENNDEKKMMDKYPANYAPLNNSPMRWEPVFVADAYVSYGISDNVKMELLATNILDEYYVDPLTRTMMPAPGRTLRLNFTSHF
>NZ_CP048621.1|WP_004918928.1|2814626_2815382_-|energy-transducer-TonB
MKKTRFLTVTLSVLLHAVIIMGFIHLAQEEKNQQHQAVMDAPVMSIALTHAIEETAPTDSDMTPMVEPEAEIVPPVVVETAQVVLPKKEKKIERPKKKVKEPNKRLSEKKEVEQQKVSTNKITKSAITPQQSQQGETAASSPSMGKVGQPKNGMSNLADTQQINAYREKLRQEVERHKRYPRRAKSMKKQGVAQVQFRLTETGEITSARIVSSSGSELLDNAALAAVEKSQSVGKPPSGFAHIVTFKIEFK
>NZ_CP048621.1|WP_004918937.1|2814175_2814607_+|hypothetical-protein
MKKYLLPISLFVNVVLLITIIVVGALFFNLKSKIDSTVEQIKNGQYAELVKDNTANLIPEGLKNFKKIEPNQSQCDYFYQQIDSLIGYLEENPTIAGSEKYVKQLNNLKKSAEKTPSTLKETACEKGISTINFIGEKISTATE
>NZ_CP048621.1|WP_104873406.1|2811508_2813152_+|thiamine-pyrophosphate-binding-protein
MYETITVGEAIARTLEQYQVSTVYGVISIHNLPIADAIGRRGVIDFTPSRGEAGAVTMADAHGRFTGLGVALTSTGAGAGNAVGSMIEAMNACSPIIHITGQVEKAYLDMDAGFIHETRDQLGFLKASSKQAFRVHSAEQAVAVLHKAIQVAQTVPCGPVSIEIPIDIQSAQVPLSLLSAPLTVQPLPEATADQVDAIWQKLQHAQRPLLWIGGGALHASDAIKKLADQGVAVISSTHGRGILSDEHPFSLRAFHNADAIDKLMRSCDITLVAGSRLRSNETKTWSLPLPQPLIQIDIDPLAANRNYRADLVVTADCHSILNALASKLEQSKRTISPQWQQQVQEATQQAEAQLRAQCGPYSQLSDAVEQALPDHGIFVRDITVSGSLWGSRLLKATQPLHNIHSLAGAIGLGLAMAIGSAKANPQTPVIGLVGDGGLMLGIGELATMAQEQLPIVLLIMNDHGYGVMRGIQEKYFADRQYYNELLTPSFTRLAESMGIKALTVDKAEDFKSTLQRAVELKQPVVVEVLMENIGKMNFSGPPQKKLF
>NZ_CP048621.1|WP_104873407.1|2809970_2811440_+|aldehyde-dehydrogenase
MKKLDIFVGGRWQQGRGNEMCSRFPGDQHIIATLNSASVSDVEEAVQAAERAWRAPSWRNMPPHQRATILHNVSMLIEEQADELTRLQTLDNGKPWAEARGLVMSAAATARYFAAVCEVSGGELPPRRQPDMMTLSTYQPLGVIAAITPWNSPIASDMQKIAPALAAGNAVILKPAEATPLISLKLAELFEQAGLPSGLLSVLPGKGSIVGDALVRHPLVKKISFTGGTNTGRQLAHIAAEKLITTSLELGGKSPTIVLEDADLNLAAHGVCYGIFSSMGQACIAGSRLFVSRAVYEPFMEKLTALTQQLIIGDPRQERVHVGPLISPEHRESVIRYVNQAIAEGGTIRLGGAIPQDPNLQAGNYYLPTIIEGLNNQASVCQEEIFGPVLVVIPFDNETQLIEEANDSIYGLAAGIWTQDYTRAFKLADALDVGTVWINTYKVFSISTPFGGFKESGLGREKGLESLKAYMQQKSIFLALNPQPNRWCE
>NZ_CP048621.1|WP_104873408.1|2809162_2809957_+|aspartate-dehydrogenase
MKTLMLIGYGAMANEVIQRLPAGIELGWIVAREHHHNDIKQRFQNRVIPLSCPTHASQKPDLILECASQHAVKQYAPMVLEKGWTLAVISTGALADAQLAQTLSQKAQQHHAIFIPLSGAVAGLDGLRCAKEAAIRQVTYQSRKSPASWRNGPAENYIDLDTVTEPTVFFHGTAREAALKFPANANVAATVALYGIGMDKTKVELMVDPTTKQNSHRIEVTGDFGHFCIELNGNPLPSNPKTSLLSALSAVEICRRIADQDAII
>NZ_CP048621.1|WP_004918910.1|2823947_2824244_-|antibiotic-biosynthesis-monooxygenase
MLKVIAEDFIQLEAINIVLPLYRELVEATKREPLCIAYDLYVDQKDRGHFIFIEEWPDQAALDAHCKSEHFQRLVPMINQYQRKEPSFIFMDDALAKI
>NZ_CP048621.1|WP_163762248.1|2824431_2824974_+|sulfatase-like-hydrolase/transferase
MPKFIESIDNPAKKKLIVVHLIGSHSPFCKRISNKYDKFYKSKDLSCYVQSIKNTDLQLSLLHGILSKSKNSWSMLYFSDHGLSFIDNQQDLIHGDKHRQNFETPLFITSSDSNTREIISAQRSELNLFHLLAEWLGIHEKNIQSSCKMISNNECKDQNIAIDFDQKIIYFNELLDDSIK
>NZ_CP048621.1|WP_004918906.1|2825310_2825475_+|hypothetical-protein
MKKLLFIISILCSSAYATNTVTWCSPEPNPVTGKPDCITYTPGMGGIDSGGEGP
>NZ_CP048621.1|WP_101495226.1|2826120_2827229_-|IS3-family-transposase
MKKARFTETQIVNILKLADSGMKVEDICRQNGISNATYYNWKSKYGGMEANDVKRLKELEDENAKLKKLFAEVSLENQAMKELFGKKGLVVTEKKSCAQSLKEAGLSVIKACKLTSLPRATFYRQPLDWRKKDQVVIDAIQSVLAKSPQSGFWKCYFRLRFQGYSFNHKRVYRVYCRLGLNLKRRVKKVLPKREKRPLVIEKVPNIQWALDFVHDSLYCGKRFRTLNIIDEGTRECLAIEVDTSLPAERVIRVLERLKIDRGLPKQIRVDNGPELISANLLNYCKNNRIDLCHIQPGKPQQNGFIERFNGSFRREFLNAYLFESLSQVREMVWFWQQDYNLNRTHESLNNLPPETYRKQLEISNLKCLN
>NZ_CP048621.1|WP_004918896.1|2827992_2828220_+|HEAT-repeat-domain-containing-protein
MNHSRQKIILNTLIQLTQGTNNEVKLTAISILGDYKYAIQNEETLNRLIELCFDPNKEVAITALKSLGKLSIHFQ
>NZ_CP048621.1|WP_053110723.1|2828795_2829575_-|elongation-factor-Tu
MKAIYLLLGLLFSSFAFSAENSVMILGDDYRHTLVKELEGATFVTHGKNDSLIQQVKQAFNQDSIILVINMADGPTQNLRESILIARQSGHNSVQVYYHGKHLPKEMLNDDDFKKLMTLVVKEVNELLDLYEIQITGAYYDWERDFPEKFQLQKNIMAKFSPEPNTLMTEIHSYAYVFTKEEASDNTIITDGTVLAFACQDVIGNATVRSQDPIKRGGNYSHIVLELEKPTLIPLHARCLGTLNNTLAMAFITVLENEK
>NZ_CP048621.1|WP_004918885.1|2829969_2830464_+|hypothetical-protein
MSKFQCSCGHIIRDNTDYLSYKAYYISDQDFYDFLDELEGESRDNFASVAYKYVRDIYQCTKCNNIFIFRGDFFHEFQATQPDSHSLLISNMRDKWPGFLRGYFIKGKGEIYWETNQQSDYLTGLTREQVESTYYHKLNEFQSLGILRDAFLHVDGVMLHEYNR
>NZ_CP048621.1|WP_014658149.1|2831136_2831787_-|DUF4431-domain-containing-protein
MIRLFLFLIFVFPSITYAASFDCAKAQSNVEKLICNTPELSKADDELYVDYLQAKLVTGNSDEFKRLVKKNWELRVKNCDTKSCLLDWYHRSTIIYRNIAASQPVDEQDISEFNYYYNSPVKLRGVIRLEKPDGFLTLRTDNIISVSSKEPEDSEGEPTEWGIGALHLAPRNSDQFNQLKEIQGKKVDITCDLYHATNIHHKTPVLCSVEHYVLVK
>NZ_CP048621.1|WP_014658148.1|2832517_2833513_+|chitinase
MSSDNIINTQVVDDAAAMPDISNKKIMMGFWHNWAAGASDGYQQGQCANMNLTDIPEEYNVVAVAFMKGEGIPTFKPYNLSDAEFRRQVGVLNSQGRAVLISLGGADAHIQLKTGDEDKLTNEIIRLVETYGFDGLDIDLEQTAISSANNKTVLPAALKKVKEHYAAEGKNFIISMAPEFPYLRINGAYLDYINALEGYYDFIAPQYYNQGGDGIWVDETTSGKGAWLSQNSDAMKEDFLYYLTESLVTGTRGYTKIPPSKFVIGLPANNDAAGSGYVIDKQAVYNAFARLDAKNLSIKGLMTWSVNWDNGKSKTGVAYNWEFKTRYAALL
>NZ_CP048621.1|WP_036943804.1|2834299_2834902_-|thiamine-biosynthesis-protein-ThiJ
MFNVAIIIFDEFTDIDYFLMRDIFGRCREDWNVSVLGTKPFHTSTLGQKVETDGHVSLANQADVVLFSSGQQGVPNALADESFMQSFKLNSQQQIIGSICAGSFILHKLGLLNDIQATTHPDARNAFINMGADVEDKPLVIRGNIGTAGGCLSALYLTGWIAEKLFDSDKRRQMHRQILPANQHELYEQIIVNAITEAQH

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Crispr_ID: NZ_CP048621_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP048621_4

2830625-2830892

Orphan

I-F

Consensus_repeat	Method
GTGTACTGCCGCATAGGCAGCTTAGAAA	PILER-CR
TTTCTAAGCTGCCTATGCGGCAGTACAC	CRISPRCasFinder
TTTCTAAGCTGCCTATGCGGCAGTACAC	CRT

4 spacers

The CRISPR arrays of NZ_CP048621_4

>merge|NZ_CP048621|4|2830625-2830892|PILER-CR,CRISPRCasFinder,CRT
TTTCTAAGCTGCCTATGCGGCAGTACACGCAGGTAAGCGCGGAGAACTACAAATGTTTATTTTCTAAGCTGCCTATGCGGCAGTACACGTTTATTTGCCGGTGTGAAAGAGGGTAAGTTTTTTCTAAGCTGCCTATGCGGCAGTACACGTACACATTCCCTCCGTCTGCTAGGGTTGTCATTTCTAAGCTGCCTATGCGGCAGTACACAAAACAACGATTGCCCCTGCAAAAAATGCGCCTTTCTAAGCTGCCTATGCGGCAGTACAC

>NZ_CP048621|4|4|2830625-2830892|PILER-CR
TTTCTAAGCTGCCTATGCGGCAGTACAC	GCAGGTAAGCGCGGAGAACTACAAATGTTTAT
TTTCTAAGCTGCCTATGCGGCAGTACAC	GTTTATTTGCCGGTGTGAAAGAGGGTAAGTTT
TTTCTAAGCTGCCTATGCGGCAGTACAC	GTACACATTCCCTCCGTCTGCTAGGGTTGTCA
TTTCTAAGCTGCCTATGCGGCAGTACAC	AAAACAACGATTGCCCCTGCAAAAAATGCGCC
TTTCTAAGCTGCCTATGCGGCAGTACAC

>NZ_CP048621|4|3|2830625-2830892|CRISPRCasFinder
TTTCTAAGCTGCCTATGCGGCAGTACAC	GCAGGTAAGCGCGGAGAACTACAAATGTTTAT
TTTCTAAGCTGCCTATGCGGCAGTACAC	GTTTATTTGCCGGTGTGAAAGAGGGTAAGTTT
TTTCTAAGCTGCCTATGCGGCAGTACAC	GTACACATTCCCTCCGTCTGCTAGGGTTGTCA
TTTCTAAGCTGCCTATGCGGCAGTACAC	AAAACAACGATTGCCCCTGCAAAAAATGCGCC
TTTCTAAGCTGCCTATGCGGCAGTACAC

>NZ_CP048621|4|3|2830625-2830892|CRT
TTTCTAAGCTGCCTATGCGGCAGTACAC	GCAGGTAAGCGCGGAGAACTACAAATGTTTAT
TTTCTAAGCTGCCTATGCGGCAGTACAC	GTTTATTTGCCGGTGTGAAAGAGGGTAAGTTT
TTTCTAAGCTGCCTATGCGGCAGTACAC	GTACACATTCCCTCCGTCTGCTAGGGTTGTCA
TTTCTAAGCTGCCTATGCGGCAGTACAC	AAAACAACGATTGCCCCTGCAAAAAATGCGCC
TTTCTAAGCTGCCTATGCGGCAGTACAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP048621.1\|WP_004918885.1\|2829969_2830464_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048621.1\|WP_163762059.1\|2840688_2842467_+\|AIPR-family-protein	unknown	unknown	gnl\|CDD\|378452
NZ_CP048621.1\|WP_163762058.1\|2835497_2835836_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048621.1\|WP_163762248.1\|2824431_2824974_+\|sulfatase-like-hydrolase/transferase	unknown	unknown	gnl\|CDD\|293741
NZ_CP048621.1\|WP_163762060.1\|2842884_2843972_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|366234
NZ_CP048621.1\|WP_036943814.1\|2822084_2822450_+\|DUF305-domain-containing-protein	unknown	unknown	gnl\|CDD\|226074
NZ_CP048621.1\|WP_104873403.1\|2819975_2820740_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|366565
NZ_CP048621.1\|WP_060561331.1\|2837586_2838243_+\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NZ_CP048621.1\|WP_004918906.1\|2825310_2825475_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048621.1\|WP_014658135.1\|2845516_2845909_-\|M15-family-metallopeptidase	unknown	unknown	gnl\|CDD\|350620
NZ_CP048621.1\|WP_004918910.1\|2823947_2824244_-\|antibiotic-biosynthesis-monooxygenase	unknown	unknown	gnl\|CDD\|224278
NZ_CP048621.1\|WP_004918896.1\|2827992_2828220_+\|HEAT-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|379311
NZ_CP048621.1\|WP_163762061.1\|2845069_2845498_-\|lysis-protein	unknown	unknown	gnl\|CDD\|281263
NZ_CP048621.1\|WP_014658149.1\|2831136_2831787_-\|DUF4431-domain-containing-protein	unknown	unknown	gnl\|CDD\|373092
NZ_CP048621.1\|WP_053110723.1\|2828795_2829575_-\|elongation-factor-Tu	unknown	unknown	gnl\|CDD\|177010
NZ_CP048621.1\|WP_101495226.1\|2826120_2827229_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|372671
NZ_CP048621.1\|WP_014658148.1\|2832517_2833513_+\|chitinase	unknown	unknown	gnl\|CDD\|226000
NZ_CP048621.1\|WP_163762249.1\|2838760_2840536_+\|replication-endonuclease	unknown	unknown	gnl\|CDD\|336220
NZ_CP048621.1\|WP_036943804.1\|2834299_2834902_-\|thiamine-biosynthesis-protein-ThiJ	unknown	unknown	gnl\|CDD\|153229
NZ_CP048621.1\|WP_036943812.1\|2822575_2823049_-\|membrane-protein	unknown	unknown	gnl\|CDD\|378715

Protein	Function_ID	Function_description	E-value
NZ_CP048621.1\|WP_163762248.1\|2824431_2824974_+\|sulfatase-like-hydrolase/transferase	gnl\|CDD\|293741	cd16017, LptA, Lipooligosaccharide Phosphoethanolamine Transferase A (LptA) or Lipid A Phosphoethanolamine Transferase. Lipooligosaccharide Phosphoethanolamine Transferase A (LptA) or Lipid A Phosphoethanolamine Transferase catalyzes the modification of the lipid A headgroups by phosphoethanolamine (PEA) or 4-amino-arabinose residues. Lipopolysaccharides, also called endotoxins, protect bacterial pathogens from antimicrobial peptides and have roles in virulence. The PEA modified lipid A increases resistance to the cationic cyclic polypeptide antibiotic, polymyxin. Lipid A PEA transferases usually consist of a transmembrane domain anchoring the enzyme to the periplasmic face of the cytoplasmic membrane.	2.73448e-33
NZ_CP048621.1\|WP_163762060.1\|2842884_2843972_-\|IS3-family-transposase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	8.21672e-28
NZ_CP048621.1\|WP_036943814.1\|2822084_2822450_+\|DUF305-domain-containing-protein	gnl\|CDD\|226074	COG3544, COG3544, Uncharacterized protein conserved in bacteria [Function unknown].	3.11722e-22
NZ_CP048621.1\|WP_104873403.1\|2819975_2820740_-\|hypothetical-protein	gnl\|CDD\|366565	pfam01298, TbpB_B_D, C-lobe and N-lobe beta barrels of Tf-binding protein B. Bacterial lipoproteins represent a large group of specialized membrane proteins that perform a variety of functions including maintenance and stabilization of the cell envelope, protein targeting and transit to the outer membrane, membrane biogenesis, and cell adherence. Pathogenic Gram-negative bacteria within the Neisseriaceae and Pasteurellaceae families rely on a specialized uptake system, characterized by an essential surface receptor complex that acquires iron from host transferrin (Tf) and transports the iron across the outer membrane. They have an iron uptake system composed of surface exposed lipoprotein, Tf-binding protein B (TbpB), and an integral outer-membrane protein, Tf-binding protein A (TbpA), that together function to extract iron from the host iron binding glycoprotein (Tf). TbpB is a bilobed (N and C lobe) lipid-anchored protein with each lobe consisting of an eight-stranded beta barrel flanked by a handle domain made up of four (N lobe) or eight (C lobe) beta strands. TbpB extends from the outer membrane surface by virtue of an N-terminal peptide region that is anchored to the outer membrane by fatty acyl chains on the N-terminal cysteine and is involved in the initial capture of iron-loaded Tf. This domain family is found in C and N lobe eight stranded beta barrel region of TbpB proteins. The eight-stranded barrel domains in N and C lobe draw comparisons to eight-stranded beta barrel outer-membrane protein W (OmpW). However, the barrel domains of TbpB have the hydrophobic residues line the inner surface of the beta barrels to create a stable hydrophobic core.	2.04365e-05
NZ_CP048621.1\|WP_060561331.1\|2837586_2838243_+\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	4.21963e-14
NZ_CP048621.1\|WP_014658148.1\|2832517_2833513_+\|chitinase	gnl\|CDD\|226000	COG3469, COG3469, Chitinase [Carbohydrate transport and metabolism].	1.0477e-165
NZ_CP048621.1\|WP_014658135.1\|2845516_2845909_-\|M15-family-metallopeptidase	gnl\|CDD\|350620	cd14845, L-Ala-D-Glu_peptidase_like, L-Ala-D-Glu peptidase, also known as L-alanyl-D-glutamate endopeptidase. This L-Ala-D-Glu peptidase family includes L-alanyl-D-glutamate peptidase (bacteriophage T5) (also known as L-alanoyl-D-glutamate endopeptidase), and Ply118 and Ply500 L-Ala-D-Glu peptidase. Bacteriophage endolysin degrades the peptidoglycan of the bacterial host from within, leading to cell lysis and release of progeny virions. The bacteriophage endolysin Ply118 cleaves between L-Ala and D-Glu residues of Listeria cell wall peptidoglycan. This family belongs to the MEROPS peptidase M15 subfamily C.	3.14672e-40
NZ_CP048621.1\|WP_004918910.1\|2823947_2824244_-\|antibiotic-biosynthesis-monooxygenase	gnl\|CDD\|224278	COG1359, COG1359, Uncharacterized conserved protein [Function unknown].	4.55236e-22
NZ_CP048621.1\|WP_004918896.1\|2827992_2828220_+\|HEAT-repeat-domain-containing-protein	gnl\|CDD\|379311	pfam13646, HEAT_2, HEAT repeats. This family includes multiple HEAT repeats.	5.29088e-06
NZ_CP048621.1\|WP_163762061.1\|2845069_2845498_-\|lysis-protein	gnl\|CDD\|281263	pfam03245, Phage_lysis, Bacteriophage Rz lysis protein. This protein is involved in host lysis. This family is not considered to be a peptidase according to the MEROPs database. This family Rz and the Rz1 protein (pfam06085) represent a unique example of two genes located in different reading frames in the same nucleotide sequence, which encode different proteins that are both required in the same physiological pathway.	8.13798e-25
NZ_CP048621.1\|WP_014658149.1\|2831136_2831787_-\|DUF4431-domain-containing-protein	gnl\|CDD\|373092	pfam14485, DUF4431, Domain of unknown function (DUF4431).	3.0978e-14
NZ_CP048621.1\|WP_053110723.1\|2828795_2829575_-\|elongation-factor-Tu	gnl\|CDD\|177010	CHL00071, tufA, elongation factor Tu.	4.04022e-08
NZ_CP048621.1\|WP_101495226.1\|2826120_2827229_-\|IS3-family-transposase	gnl\|CDD\|372671	pfam13683, rve_3, Integrase core domain.	2.75833e-25
NZ_CP048621.1\|WP_163762059.1\|2840688_2842467_+\|AIPR-family-protein	gnl\|CDD\|378452	pfam10592, AIPR, AIPR protein. This family of proteins was identified in as an abortive infection phage resistance protein often found in restriction modification system operons.	4.9644e-29
NZ_CP048621.1\|WP_163762249.1\|2838760_2840536_+\|replication-endonuclease	gnl\|CDD\|336220	pfam05840, Phage_GPA, Bacteriophage replication gene A protein (GPA). This family consists of a group of bacteriophage replication gene A protein (GPA) like sequences from both viruses and bacteria. The members of this family are likely to be endonucleases.	3.12443e-92
NZ_CP048621.1\|WP_036943804.1\|2834299_2834902_-\|thiamine-biosynthesis-protein-ThiJ	gnl\|CDD\|153229	cd03135, GATase1_DJ-1, Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1. Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1. DJ-1 is involved in multiple physiological processes including cancer, Parkinson's disease and male fertility. It is unclear how DJ-1 functions in these. DJ-1 has been shown to possess chaperone activity. DJ-1 is preferentially expressed in the testis and moderately in other tissues; it is induced together with genes involved in oxidative stress response. The Drosophila homologue (DJ-1A) plays an essential role in oxidative stress response and neuronal maintenance. Inhibition of DJ-1A function through RNAi, results in the cellular accumulation of reactive oxygen species, organismal hypersensitivity to oxidative stress, and dysfunction and degeneration of dopaminergic and photoreceptor neurons. DJ-1 has lacks enzymatic activity and the catalytic triad of typical GATase1 domains, however it does contain the highly conserved cysteine located at the nucelophile elbow region typical of these domains. This cysteine been proposed to be a site of regulation of DJ-1 activity by oxidation. DJ-1 is a dimeric enzyme.	1.73702e-16
NZ_CP048621.1\|WP_036943812.1\|2822575_2823049_-\|membrane-protein	gnl\|CDD\|378715	pfam11776, RcnB, Nickel/cobalt transporter regulator. RcnB is a family of Proteobacteria proteins. RcnB is required for maintaining metal ion homeostasis, in conjunction with the efflux pump RcnA, family NicO, pfam03824.	0.00396084

>NZ_CP048621.1|WP_004918885.1|2829969_2830464_+|hypothetical-protein
MSKFQCSCGHIIRDNTDYLSYKAYYISDQDFYDFLDELEGESRDNFASVAYKYVRDIYQCTKCNNIFIFRGDFFHEFQATQPDSHSLLISNMRDKWPGFLRGYFIKGKGEIYWETNQQSDYLTGLTREQVESTYYHKLNEFQSLGILRDAFLHVDGVMLHEYNR
>NZ_CP048621.1|WP_053110723.1|2828795_2829575_-|elongation-factor-Tu
MKAIYLLLGLLFSSFAFSAENSVMILGDDYRHTLVKELEGATFVTHGKNDSLIQQVKQAFNQDSIILVINMADGPTQNLRESILIARQSGHNSVQVYYHGKHLPKEMLNDDDFKKLMTLVVKEVNELLDLYEIQITGAYYDWERDFPEKFQLQKNIMAKFSPEPNTLMTEIHSYAYVFTKEEASDNTIITDGTVLAFACQDVIGNATVRSQDPIKRGGNYSHIVLELEKPTLIPLHARCLGTLNNTLAMAFITVLENEK
>NZ_CP048621.1|WP_004918896.1|2827992_2828220_+|HEAT-repeat-domain-containing-protein
MNHSRQKIILNTLIQLTQGTNNEVKLTAISILGDYKYAIQNEETLNRLIELCFDPNKEVAITALKSLGKLSIHFQ
>NZ_CP048621.1|WP_101495226.1|2826120_2827229_-|IS3-family-transposase
MKKARFTETQIVNILKLADSGMKVEDICRQNGISNATYYNWKSKYGGMEANDVKRLKELEDENAKLKKLFAEVSLENQAMKELFGKKGLVVTEKKSCAQSLKEAGLSVIKACKLTSLPRATFYRQPLDWRKKDQVVIDAIQSVLAKSPQSGFWKCYFRLRFQGYSFNHKRVYRVYCRLGLNLKRRVKKVLPKREKRPLVIEKVPNIQWALDFVHDSLYCGKRFRTLNIIDEGTRECLAIEVDTSLPAERVIRVLERLKIDRGLPKQIRVDNGPELISANLLNYCKNNRIDLCHIQPGKPQQNGFIERFNGSFRREFLNAYLFESLSQVREMVWFWQQDYNLNRTHESLNNLPPETYRKQLEISNLKCLN
>NZ_CP048621.1|WP_004918906.1|2825310_2825475_+|hypothetical-protein
MKKLLFIISILCSSAYATNTVTWCSPEPNPVTGKPDCITYTPGMGGIDSGGEGP
>NZ_CP048621.1|WP_163762248.1|2824431_2824974_+|sulfatase-like-hydrolase/transferase
MPKFIESIDNPAKKKLIVVHLIGSHSPFCKRISNKYDKFYKSKDLSCYVQSIKNTDLQLSLLHGILSKSKNSWSMLYFSDHGLSFIDNQQDLIHGDKHRQNFETPLFITSSDSNTREIISAQRSELNLFHLLAEWLGIHEKNIQSSCKMISNNECKDQNIAIDFDQKIIYFNELLDDSIK
>NZ_CP048621.1|WP_004918910.1|2823947_2824244_-|antibiotic-biosynthesis-monooxygenase
MLKVIAEDFIQLEAINIVLPLYRELVEATKREPLCIAYDLYVDQKDRGHFIFIEEWPDQAALDAHCKSEHFQRLVPMINQYQRKEPSFIFMDDALAKI
>NZ_CP048621.1|WP_036943812.1|2822575_2823049_-|membrane-protein
MNKLFRMCNLLLLTASFSMVSLSSYADPNGGHGHGQGKEHQKNKPNKGHNGNGKEKADHLSLNKSNSISVSLTYNEARALALDSGITGYHALPPGIAKNLARGKPLPPGIAKKVVPPSMLVQLPHYPGYEWSIVGNDLVLIALSTAVVTSIINNVFD
>NZ_CP048621.1|WP_036943814.1|2822084_2822450_+|DUF305-domain-containing-protein
MKKMLPIAAILTISIASFSSFANSNHSMHAQAPASNEMQKELNQSMDKMHADMAKSMNEENADIAFAQGMIAHHLGAIDMAKIELKYGTDPEMRKLAEEIINAQGPEIEQMQKWLEKNKTK
>NZ_CP048621.1|WP_104873403.1|2819975_2820740_-|hypothetical-protein
MARNIMKNLSLTALTIVLSSVAFSTSGETVSGQSQAYDSNGVEVNVGKTQFAQGTHSGVIGDPGVGLKTIANGTRIGFSGFKSLAPENEQGVNVLPASSGGHGGAMGEFHFTQVANAEVYFGDWSKTGSVGDQSHTAFFSGKEATESVPTAGQAEYTIAGINQFDGQGKLSGVFNADFGSKKYTGALNGQSLNITMNGNIQDKGQFSGSAIANGSIQGKSSGQFFGKNADVVAGITTFDSDHTKDTSFGGSKVQ
>NZ_CP048621.1|WP_014658149.1|2831136_2831787_-|DUF4431-domain-containing-protein
MIRLFLFLIFVFPSITYAASFDCAKAQSNVEKLICNTPELSKADDELYVDYLQAKLVTGNSDEFKRLVKKNWELRVKNCDTKSCLLDWYHRSTIIYRNIAASQPVDEQDISEFNYYYNSPVKLRGVIRLEKPDGFLTLRTDNIISVSSKEPEDSEGEPTEWGIGALHLAPRNSDQFNQLKEIQGKKVDITCDLYHATNIHHKTPVLCSVEHYVLVK
>NZ_CP048621.1|WP_014658148.1|2832517_2833513_+|chitinase
MSSDNIINTQVVDDAAAMPDISNKKIMMGFWHNWAAGASDGYQQGQCANMNLTDIPEEYNVVAVAFMKGEGIPTFKPYNLSDAEFRRQVGVLNSQGRAVLISLGGADAHIQLKTGDEDKLTNEIIRLVETYGFDGLDIDLEQTAISSANNKTVLPAALKKVKEHYAAEGKNFIISMAPEFPYLRINGAYLDYINALEGYYDFIAPQYYNQGGDGIWVDETTSGKGAWLSQNSDAMKEDFLYYLTESLVTGTRGYTKIPPSKFVIGLPANNDAAGSGYVIDKQAVYNAFARLDAKNLSIKGLMTWSVNWDNGKSKTGVAYNWEFKTRYAALL
>NZ_CP048621.1|WP_036943804.1|2834299_2834902_-|thiamine-biosynthesis-protein-ThiJ
MFNVAIIIFDEFTDIDYFLMRDIFGRCREDWNVSVLGTKPFHTSTLGQKVETDGHVSLANQADVVLFSSGQQGVPNALADESFMQSFKLNSQQQIIGSICAGSFILHKLGLLNDIQATTHPDARNAFINMGADVEDKPLVIRGNIGTAGGCLSALYLTGWIAEKLFDSDKRRQMHRQILPANQHELYEQIIVNAITEAQH
>NZ_CP048621.1|WP_163762058.1|2835497_2835836_+|hypothetical-protein
MKNKHTTQDYMQKFMIKQNEVIVPYLRQVIHPTELKSVFCIYEMIEQGENIYTYLVNGEMVVIFEISRIDHSITHDLTLPIREYAQEIKGRQWHRYIRELQAFAEQEDSQVN
>NZ_CP048621.1|WP_060561331.1|2837586_2838243_+|CPBP-family-intramembrane-metalloprotease
MISMDRVLHSLVCVSFFVGWYLIQYALLAFPGITTYNDALAAWPLFTILFILPYSLFSRAYYQKQTGLMPFGTVRFSDLRLPIIAMVILSVATMFYGEDETSILEMLALSPLHQFILVVSVVFAAPIIEEIIFRGFLLNAGMGYGPNGKHVMIIITSVLFAMIHHQYNSPATFIMIFVMSVIFCHVRIQTNSLMAPIILHMINNAVAMLLLFLLNDTP
>NZ_CP048621.1|WP_163762249.1|2838760_2840536_+|replication-endonuclease
MFDCPAVTSLDARKVIAAVQRLTNTDYWYRKLKAHRTQWLEALMIANMDVCQNRNPYASKQAIRAVQAQRLSNMQYLQGMDIEDVETGERFDLFDKVMASVSNPEIRRMELMAQMAGIERVAKERGDIGMFITRTCPSKYHPTKLRKRKKDVIAALNGKWKNEAYTPKDGQQYLVKVWSRIRSAFNDNNINVYGVRVVEPHHDGTPHWHMLLFVDKASRAKAIEIMRKRALKEDGDEAGAHKYRFECKHMNRGGAVGYIAKYIAKNIDGYALDGEIDNETGKDLKSMAAAVTAWASTWRIPQFHFYKLPSKGAYRECRRLPRGVSIADQLGDVAERVRAAADGGDFFEYVMSQGGPCIRRKEETIRVAREVSDVNTYGEEVQKVVGIYNQLATGKPTLKTRERQYKIVKKNTDAANDGLLKSAIGAPRSPVNNCRSRITSNLSDVQFYEPEHCSGEVCNIEEYGFAFIETDAQNAAGSEISQGRQQRQVSRIELNEEESELRPEICSFMQKTGFDLPTETMANMFIKGMAIKDDDRIFRFDGRQVRVIESELVIKKRIQAVKMKKEADLQRNRERCIEALVRIKEKYNNEP
>NZ_CP048621.1|WP_163762059.1|2840688_2842467_+|AIPR-family-protein
MAFVTELTQEDNATPAMATANLTAIRLGVTLRERFEEHIHKRECSIGQSDYEIKMASRAIAAFVIHHLSQVDDYISGASVCDSSHDGGIDAIHVNHTEKTVVVVQSKFSQSGSSTWTNADFLVFKQACDHLIEEEYERFDTILQSKREDISKALSSIDYKFLFVMAHTGKRGAANIILSDMQQWQNELNESASLTSELPNNELPFQVHLVSSEDITQWRHAQSSAAVDLDDVELEQYGKIETPYTAFFGIISGDQLSEWWKLHSSKLFTKNIRNLLGKTEVNEAIKETAQNDPDNFWFYNNGITVLVRSIEPHRRNKTNQRDVGRFNFRDVSVINGAQTVSSIGSLDTVDEDTLTKIKVQARFIQIPQGASEDIINLITRANNHQNRVLGRDFASQHPQQLRLRDELIIEGYIYQLLRSDVSTDELGEKHIDIDEALDALACLSCRSSTLSLLKVQRGKFFDNLEGPAYKALFNSSVSGVSLINAVLHHRVIDNKIKEMLVSTNRQEDKKRYGILTHANRVFAGYILDNTPRLKTAREIMTVNVNRIHDELERILSVTEHFIEAEYPTAYPARFFSNVDKISLTLEKLREES
>NZ_CP048621.1|WP_163762060.1|2842884_2843972_-|IS3-family-transposase
MKKARFTDSQIITILKQAEAGTPVSELCREHGMSNASFYKWRSRFGGMDASMMTRLKELEEENRRLKKMYAEERLKAEIIQEAMGKKVVKPSHRKRMAQEAVKIRNISVRFACQLFVVSESCYRYQAKLSKENEAIADWLIRITDSQRNWGFGLCFLYLRNVKNLRFNHKRVYRIYCALSLNMRIKPKKRLKRDKPEPLTVPETSNECWSMDFMHDQLSDGRSVRLLNIIDDFNREALAIEVDFSLPASRVVRVLEQLIEWKGKPVSIRCDNGPEYTSNILISSANLQDIKINFIQPGNPQQNAYIERYNRTVRYEWLGQYLFSSLDELQDYATRWQWFYNHERPNMALNGYTPMQHLQRMT
>NZ_CP048621.1|WP_163762061.1|2845069_2845498_-|lysis-protein
MKFDKSFWLFIMVVGLGWWVVTVHDSNNLLKKENSKLIDSIQNYERRIDSLHELDTKHTQELTNAKTEIDKLRVAAERNPERVYIKASCKKAEGTTATGLDDAITARPTDSAIRNYWLLRERIAESEQMIKGLQEYVKKECW
>NZ_CP048621.1|WP_014658135.1|2845516_2845909_-|M15-family-metallopeptidase
MSKFKFSKRSEENLRGVHPDLVKVTRRAIELTNIDFMVIEGKRTEARQRQLVKNGASQTMNSRHLTGHAVDCAPLVNREIPWNDWSKFKLVADAMLQAAKELNVDLEWGGNWKSFKDGPHFQLTHKSYPA

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Crispr_ID: NZ_CP048621_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP048621_5

2849367-2849814

Orphan

I-F

Consensus_repeat	Method
GTTCACTGCCGTATAGGCAGCTTAGAAA	PILER-CR
TTTCTAAGCTGCCTATACGGCAGTGAAC	CRISPRCasFinder
TTTCTAAGCTGCCTATACGGCAGTGAAC	CRT

7 spacers

The CRISPR arrays of NZ_CP048621_5

>merge|NZ_CP048621|5|2849367-2849814|PILER-CR,CRISPRCasFinder,CRT
TTTCTAAGCTGCCTATACGGCAGTGAACAAGATAATTGCTATCCAAAACGTGTTTATAGATTTCTAAGCTGCCTATACGGCAGTGAACCAGTTGAGGCAGGTTGTGAGCCTTGTTTGTATTTTCTAAGCTGCCTATACGGCAGTGAACGTCTTGGTGGTGCGTCAGCTGGCATGGCAATATTTCTAAGCTGCCTATACGGCAGTGAACTGACATAAATACTACTAATTCCTGAGCTAAGTTTTCTAAGCTGCCTATACGGCAGTGAACAGCGCGAAAATAGAAGCGCGCACCTGCTTTAATTTCTAAGCTGCCTATACGGCAGTGAACACTCGCACCATGATCACATCGCCCCGAAGTCATTTCTAAGCTGCCTATACGGCAGTGAACATGAGCAAATGGCTATTGATGCCTTGTTTAATTTTCTAAGCTGCCTATACGGCAGTGAAC

>NZ_CP048621|5|5|2849367-2849814|PILER-CR
TTTCTAAGCTGCCTATACGGCAGTGAAC	AAGATAATTGCTATCCAAAACGTGTTTATAGA
TTTCTAAGCTGCCTATACGGCAGTGAAC	CAGTTGAGGCAGGTTGTGAGCCTTGTTTGTAT
TTTCTAAGCTGCCTATACGGCAGTGAAC	GTCTTGGTGGTGCGTCAGCTGGCATGGCAATA
TTTCTAAGCTGCCTATACGGCAGTGAAC	TGACATAAATACTACTAATTCCTGAGCTAAGT
TTTCTAAGCTGCCTATACGGCAGTGAAC	AGCGCGAAAATAGAAGCGCGCACCTGCTTTAA
TTTCTAAGCTGCCTATACGGCAGTGAAC	ACTCGCACCATGATCACATCGCCCCGAAGTCA
TTTCTAAGCTGCCTATACGGCAGTGAAC	ATGAGCAAATGGCTATTGATGCCTTGTTTAAT
TTTCTAAGCTGCCTATACGGCAGTGAAC

>NZ_CP048621|5|4|2849367-2849814|CRISPRCasFinder
TTTCTAAGCTGCCTATACGGCAGTGAAC	AAGATAATTGCTATCCAAAACGTGTTTATAGA
TTTCTAAGCTGCCTATACGGCAGTGAAC	CAGTTGAGGCAGGTTGTGAGCCTTGTTTGTAT
TTTCTAAGCTGCCTATACGGCAGTGAAC	GTCTTGGTGGTGCGTCAGCTGGCATGGCAATA
TTTCTAAGCTGCCTATACGGCAGTGAAC	TGACATAAATACTACTAATTCCTGAGCTAAGT
TTTCTAAGCTGCCTATACGGCAGTGAAC	AGCGCGAAAATAGAAGCGCGCACCTGCTTTAA
TTTCTAAGCTGCCTATACGGCAGTGAAC	ACTCGCACCATGATCACATCGCCCCGAAGTCA
TTTCTAAGCTGCCTATACGGCAGTGAAC	ATGAGCAAATGGCTATTGATGCCTTGTTTAAT
TTTCTAAGCTGCCTATACGGCAGTGAAC

>NZ_CP048621|5|4|2849367-2849814|CRT
TTTCTAAGCTGCCTATACGGCAGTGAAC	AAGATAATTGCTATCCAAAACGTGTTTATAGA
TTTCTAAGCTGCCTATACGGCAGTGAAC	CAGTTGAGGCAGGTTGTGAGCCTTGTTTGTAT
TTTCTAAGCTGCCTATACGGCAGTGAAC	GTCTTGGTGGTGCGTCAGCTGGCATGGCAATA
TTTCTAAGCTGCCTATACGGCAGTGAAC	TGACATAAATACTACTAATTCCTGAGCTAAGT
TTTCTAAGCTGCCTATACGGCAGTGAAC	AGCGCGAAAATAGAAGCGCGCACCTGCTTTAA
TTTCTAAGCTGCCTATACGGCAGTGAAC	ACTCGCACCATGATCACATCGCCCCGAAGTCA
TTTCTAAGCTGCCTATACGGCAGTGAAC	ATGAGCAAATGGCTATTGATGCCTTGTTTAAT
TTTCTAAGCTGCCTATACGGCAGTGAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP048621.1\|WP_014658102.1\|2859154_2859421_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048621.1\|WP_014658106.1\|2851622_2852171_-\|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase	unknown	unknown	gnl\|CDD\|182763
NZ_CP048621.1\|WP_014658103.1\|2858051_2858468_-\|phosphate-starvation-inducible-protein-PsiE	unknown	unknown	gnl\|CDD\|235075
NZ_CP048621.1\|WP_014658101.1\|2861081_2863871_-\|DUF2339-domain-containing-protein	unknown	unknown	gnl\|CDD\|378390
NZ_CP048621.1\|WP_014658135.1\|2845516_2845909_-\|M15-family-metallopeptidase	unknown	unknown	gnl\|CDD\|350620
NZ_CP048621.1\|WP_163762064.1\|2854027_2854714_-\|response-regulator	unknown	unknown	gnl\|CDD\|236538
NZ_CP048621.1\|WP_163762063.1\|2847842_2848622_-\|antitermination-protein	unknown	unknown	gnl\|CDD\|367572
NZ_CP048621.1\|WP_163762065.1\|2856203_2857757_-\|AbgT-family-transporter	unknown	unknown	gnl\|CDD\|225525
NZ_CP048621.1\|WP_014658133.1\|2846664_2846997_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048621.1\|WP_004918794.1\|2852228_2854061_-\|excinuclease-ABC-subunit-UvrC	unknown	unknown	gnl\|CDD\|234792
NZ_CP048621.1\|WP_120752678.1\|2846360_2846480_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048621.1\|WP_141173636.1\|2848666_2849023_-\|DUF968-domain-containing-protein	unknown	unknown	gnl\|CDD\|374800
NZ_CP048621.1\|WP_163762061.1\|2845069_2845498_-\|lysis-protein	unknown	unknown	gnl\|CDD\|281263
NZ_CP048621.1\|WP_072502186.1\|2854935_2856168_-\|peptidase-T	unknown	unknown	gnl\|CDD\|237371
NZ_CP048621.1\|WP_004918784.1\|2858676_2859081_-\|GFA-family-protein	unknown	unknown	gnl\|CDD\|226314
NZ_CP048621.1\|WP_163762062.1\|2847329_2847806_-\|DUF1643-domain-containing-protein	unknown	unknown	gnl\|CDD\|377919
NZ_CP048621.1\|WP_004918779.1\|2859622_2861095_-\|DUF3999-family-protein	unknown	unknown	gnl\|CDD\|372507
NZ_CP048621.1\|WP_105874340.1\|2845901_2846150_-\|holin	unknown	unknown	gnl\|CDD\|374352
NZ_CP048621.1\|WP_163762060.1\|2842884_2843972_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|366234
NZ_CP048621.1\|WP_163762059.1\|2840688_2842467_+\|AIPR-family-protein	unknown	unknown	gnl\|CDD\|378452

Protein	Function_ID	Function_description	E-value
NZ_CP048621.1\|WP_014658106.1\|2851622_2852171_-\|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase	gnl\|CDD\|182763	PRK10832, PRK10832, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase.	4.25255e-102
NZ_CP048621.1\|WP_014658103.1\|2858051_2858468_-\|phosphate-starvation-inducible-protein-PsiE	gnl\|CDD\|235075	PRK02833, PRK02833, phosphate-starvation-inducible protein PsiE; Provisional.	7.8663e-52
NZ_CP048621.1\|WP_014658135.1\|2845516_2845909_-\|M15-family-metallopeptidase	gnl\|CDD\|350620	cd14845, L-Ala-D-Glu_peptidase_like, L-Ala-D-Glu peptidase, also known as L-alanyl-D-glutamate endopeptidase. This L-Ala-D-Glu peptidase family includes L-alanyl-D-glutamate peptidase (bacteriophage T5) (also known as L-alanoyl-D-glutamate endopeptidase), and Ply118 and Ply500 L-Ala-D-Glu peptidase. Bacteriophage endolysin degrades the peptidoglycan of the bacterial host from within, leading to cell lysis and release of progeny virions. The bacteriophage endolysin Ply118 cleaves between L-Ala and D-Glu residues of Listeria cell wall peptidoglycan. This family belongs to the MEROPS peptidase M15 subfamily C.	3.14672e-40
NZ_CP048621.1\|WP_163762064.1\|2854027_2854714_-\|response-regulator	gnl\|CDD\|236538	PRK09483, PRK09483, response regulator; Provisional.	4.39106e-52
NZ_CP048621.1\|WP_163762063.1\|2847842_2848622_-\|antitermination-protein	gnl\|CDD\|367572	pfam03589, Antiterm, Antitermination protein.	1.93172e-36
NZ_CP048621.1\|WP_163762065.1\|2856203_2857757_-\|AbgT-family-transporter	gnl\|CDD\|225525	COG2978, AbgT, Putative p-aminobenzoyl-glutamate transporter [Coenzyme metabolism].	0
NZ_CP048621.1\|WP_004918794.1\|2852228_2854061_-\|excinuclease-ABC-subunit-UvrC	gnl\|CDD\|234792	PRK00558, uvrC, excinuclease ABC subunit UvrC.	0
NZ_CP048621.1\|WP_014658101.1\|2861081_2863871_-\|DUF2339-domain-containing-protein	gnl\|CDD\|378390	pfam10101, DUF2339, Predicted membrane protein (DUF2339). This domain, found in various hypothetical bacterial proteins, has no known function.	7.14631e-86
NZ_CP048621.1\|WP_141173636.1\|2848666_2849023_-\|DUF968-domain-containing-protein	gnl\|CDD\|374800	pfam16786, RecA_dep_nuc, Recombination enhancement, RecA-dependent nuclease. REF is a family of P1-like phage RecA-dependent nucleases. It does not appear to act as a positive RecA regulator. It is a new kind of enzyme, a RecA-dependent nuclease.	1.3674e-09
NZ_CP048621.1\|WP_163762061.1\|2845069_2845498_-\|lysis-protein	gnl\|CDD\|281263	pfam03245, Phage_lysis, Bacteriophage Rz lysis protein. This protein is involved in host lysis. This family is not considered to be a peptidase according to the MEROPs database. This family Rz and the Rz1 protein (pfam06085) represent a unique example of two genes located in different reading frames in the same nucleotide sequence, which encode different proteins that are both required in the same physiological pathway.	8.13798e-25
NZ_CP048621.1\|WP_072502186.1\|2854935_2856168_-\|peptidase-T	gnl\|CDD\|237371	PRK13381, PRK13381, peptidase T; Provisional.	0
NZ_CP048621.1\|WP_004918784.1\|2858676_2859081_-\|GFA-family-protein	gnl\|CDD\|226314	COG3791, COG3791, Uncharacterized conserved protein [Function unknown].	1.58541e-26
NZ_CP048621.1\|WP_163762062.1\|2847329_2847806_-\|DUF1643-domain-containing-protein	gnl\|CDD\|377919	pfam07799, DUF1643, Protein of unknown function (DUF1643). The members of this family are all sequences found within hypothetical proteins expressed by various bacterial species. The region concerned is approximately 150 residues long.	1.91125e-47
NZ_CP048621.1\|WP_004918779.1\|2859622_2861095_-\|DUF3999-family-protein	gnl\|CDD\|372507	pfam13163, DUF3999, Protein of unknown function (DUF3999). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 440 and 470 amino acids in length. There is a single completely conserved residue D that may be functionally important.	8.7517e-51
NZ_CP048621.1\|WP_105874340.1\|2845901_2846150_-\|holin	gnl\|CDD\|374352	pfam16083, Phage_holin_3_3, LydA holin phage, holin superfamily III. Phage_holin_3_3 is a family of small hydrophobic holin proteins with one or more transmembrane domains. Holins are encoded within the genomes of Gram-positive and Gram-negative bacteria as well as those of the bacteriophages of these organisms. Their primary function appears to be transport of murein hydrolases across the cytoplasmic membrane to the cell wall where these enzymes hydrolyze the cell wall polymer as a prelude to cell lysis. When chromosomally encoded, these enzymes are therefore autolysins. Holins may also facilitate leakage of electrolytes and nutrients from the cell cytoplasm, thereby promoting cell death. Some may catalyze export of nucleases. LydA and lydB are encoded on the dar operon. The phenotype of a rapid lysis in the absence of active LydB suggests that this protein might be an antagonist of the holin LydA.	4.96675e-08
NZ_CP048621.1\|WP_163762060.1\|2842884_2843972_-\|IS3-family-transposase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	8.21672e-28
NZ_CP048621.1\|WP_163762059.1\|2840688_2842467_+\|AIPR-family-protein	gnl\|CDD\|378452	pfam10592, AIPR, AIPR protein. This family of proteins was identified in as an abortive infection phage resistance protein often found in restriction modification system operons.	4.9644e-29

>NZ_CP048621.1|WP_141173636.1|2848666_2849023_-|DUF968-domain-containing-protein
MQLASYWILPRGKTNDPKTKTKEEKQWLSDVAELGCVCCRNMGYGAIPAEIHHTRTGQGIAQRASHKDVLPLCPPHHRASYDTGFHAAPKTWQQIHGTEAELLEQTKREVMELRACRI
>NZ_CP048621.1|WP_163762063.1|2847842_2848622_-|antitermination-protein
MKLENTLKNFHPKSPTFGNVAGCTSPDRITGTDIMAAMGMTESQAKFGMTAFLAKNDISEEDKFSTVEALTQYALKVAPKLVRKAAGKELGCCLIILAKMAFEDYARSAGSVFPCSACSGKGLIYKRKDVVKHPGITRLDGAVVIEPWIENEKVDELCVSCNGKGQIAHRCRCKGRGKVLDDIQTKLQGVPVFKDCPRCAGKGFNRVPSSVAYNAIKHLVPDLTQSSWSRNWKPFYEKLTAKCYIEESIAERKFSSVIK
>NZ_CP048621.1|WP_163762062.1|2847329_2847806_-|DUF1643-domain-containing-protein
MVFTEQSAKFSERNIYRYELLRIWDQDLKTVMFIGLNPSKATDKVTDRTISTCINRAKAWGFGGIIMCNLFGLVSTDPKELLNSSDPIGVENDIYLKDNADKVDMIVAMWGDLGQLNGRSEVVKKLFLEKLFYLNLNKSGEPSHTRGLSLDFEPTPFK
>NZ_CP048621.1|WP_014658133.1|2846664_2846997_+|hypothetical-protein
MERRRYIVFNVKGFSSIYNDFAGEDIPFRLMLERASGGTEVVNLNLHSKLDMMFYQTLLSYCYGSPSFSNPNNLLGPKYLRAGISLDDSGLIGFDMSNNIIPDNDVYDDN
>NZ_CP048621.1|WP_120752678.1|2846360_2846480_-|hypothetical-protein
MGVKKQEITRLFNLQHSTKIDTINQAIIAMGHRLTLSLL
>NZ_CP048621.1|WP_105874340.1|2845901_2846150_-|holin
MTMLGVAASYAYKVLNGERFSWRTFILQAIVAVFAGAIVFLASSYYQWVPEIAGGAAGFAGWSGAELIKTIEKRFLRKVSGE
>NZ_CP048621.1|WP_014658135.1|2845516_2845909_-|M15-family-metallopeptidase
MSKFKFSKRSEENLRGVHPDLVKVTRRAIELTNIDFMVIEGKRTEARQRQLVKNGASQTMNSRHLTGHAVDCAPLVNREIPWNDWSKFKLVADAMLQAAKELNVDLEWGGNWKSFKDGPHFQLTHKSYPA
>NZ_CP048621.1|WP_163762061.1|2845069_2845498_-|lysis-protein
MKFDKSFWLFIMVVGLGWWVVTVHDSNNLLKKENSKLIDSIQNYERRIDSLHELDTKHTQELTNAKTEIDKLRVAAERNPERVYIKASCKKAEGTTATGLDDAITARPTDSAIRNYWLLRERIAESEQMIKGLQEYVKKECW
>NZ_CP048621.1|WP_163762060.1|2842884_2843972_-|IS3-family-transposase
MKKARFTDSQIITILKQAEAGTPVSELCREHGMSNASFYKWRSRFGGMDASMMTRLKELEEENRRLKKMYAEERLKAEIIQEAMGKKVVKPSHRKRMAQEAVKIRNISVRFACQLFVVSESCYRYQAKLSKENEAIADWLIRITDSQRNWGFGLCFLYLRNVKNLRFNHKRVYRIYCALSLNMRIKPKKRLKRDKPEPLTVPETSNECWSMDFMHDQLSDGRSVRLLNIIDDFNREALAIEVDFSLPASRVVRVLEQLIEWKGKPVSIRCDNGPEYTSNILISSANLQDIKINFIQPGNPQQNAYIERYNRTVRYEWLGQYLFSSLDELQDYATRWQWFYNHERPNMALNGYTPMQHLQRMT
>NZ_CP048621.1|WP_163762059.1|2840688_2842467_+|AIPR-family-protein
MAFVTELTQEDNATPAMATANLTAIRLGVTLRERFEEHIHKRECSIGQSDYEIKMASRAIAAFVIHHLSQVDDYISGASVCDSSHDGGIDAIHVNHTEKTVVVVQSKFSQSGSSTWTNADFLVFKQACDHLIEEEYERFDTILQSKREDISKALSSIDYKFLFVMAHTGKRGAANIILSDMQQWQNELNESASLTSELPNNELPFQVHLVSSEDITQWRHAQSSAAVDLDDVELEQYGKIETPYTAFFGIISGDQLSEWWKLHSSKLFTKNIRNLLGKTEVNEAIKETAQNDPDNFWFYNNGITVLVRSIEPHRRNKTNQRDVGRFNFRDVSVINGAQTVSSIGSLDTVDEDTLTKIKVQARFIQIPQGASEDIINLITRANNHQNRVLGRDFASQHPQQLRLRDELIIEGYIYQLLRSDVSTDELGEKHIDIDEALDALACLSCRSSTLSLLKVQRGKFFDNLEGPAYKALFNSSVSGVSLINAVLHHRVIDNKIKEMLVSTNRQEDKKRYGILTHANRVFAGYILDNTPRLKTAREIMTVNVNRIHDELERILSVTEHFIEAEYPTAYPARFFSNVDKISLTLEKLREES
>NZ_CP048621.1|WP_014658106.1|2851622_2852171_-|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase
MKLNIPTWLTLFRVILIPFFVLAFYLPVSWGPFVCALIFVIAAVTDWFDGYLARLWKQTTKFGAFLDPVADKVMVATALVLVTESFDVWYVTLPAATMIAREIIISSLREWMAEIGKRSSVAVSWIGKFKTTAQMISLVGLLWRPNLLIENLAIALLYVAAILTFWSMYQYLKAAWSDLSEA
>NZ_CP048621.1|WP_004918794.1|2852228_2854061_-|excinuclease-ABC-subunit-UvrC
MSEQFEPKAFLKTVTNQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRTNVSSRKTEQLVKNIASIDVTVTHTETEALLLEHNYIKLYQPRYNVLLRDDKSYPYIFLSKETHPRLSMHRGAKHAKGEYFGPFPNSYAVRETLALMQKLFPIRQCEDSVYKNRSRPCLQYQIGRCLGPCVKGLVSDEEYEQQVNYVRLFLTGKDQQVLTGLIERMEKASQALRFEEAARFRDQIQAVRAVTEQQFVSGDSDDLDVIGVAFEAGLACIHVLFIRQGKVLGSRSYYPKIPADTLLEEVVQTFLGQFYLQGSENRTLPGEILLDFALPEKTLLADSLSHIAGRKIQIQTQPRGARARYLKLARTNASTALLTKLAQQSTIHQRMSSLAKTVGLDSIARMECFDISHTMGEQTVASCVVFDKNGPVKSEYRRYNITGITPGDDYAAMHQVLTRRYGKHIDESKVPDIIFIDGGKGQLGQAKDVFNSLDVDWDKNRPLLIGVAKGSDRKAGLETLFFKPEGEGVALPPDSPALHVIQHIRDESHNHAITGHRQRRAKVKNTSALESIEGVGPKRRQMLLKYMGGLQPLKNASIEEIAKVPSISYALAEKIYNALKQ
>NZ_CP048621.1|WP_163762064.1|2854027_2854714_-|response-regulator
MINIIIIDNNNILIRGLDAIFSRHKRCHIVASFPLIEQAISWNRQQKASIILINNDNCQFESLKALQTLRRTQPDVGIIIYNIHAHYSFLLKALDLGIQGILSAKIEVNEFLEAIQVVNARSKIISPDIAQSIALKRINQHEQTDLYELLSTRELEIMLLITQGIPTKQIAQVLNLSPKTVNTYRYRMFGKLNIRSDVELTHIAISYGLIVAKQGLLGCQNSLNQKLS
>NZ_CP048621.1|WP_072502186.1|2854935_2856168_-|peptidase-T
MNKLGKQLEQRFFRYLAIESQSDAAATVVPSTEGQRDLAKLLAKELESYGLKEIYIDEHAILYAVRPGNKPSAPKIGFVTHLDTVDVGLSPVIKPQTLKYEGKDLCLNAQEDIWFKASEHPEAAPYIGEEIIFSDGTSVLGADNKAAVTVVMELMDKLQQADFDCGDIYIAFVPDEEIGLRGSKIMDLSRFKVDFAYTIDCCDLGEVVYETFNAASIEVTIKGVTAHPMSAKNVLLNPIRVAHDFIGCFDRFDTPEHTEQREGYFYVTDLVANPDNAKIKMAIRDFDRNSYEARKRYIGEAIELIRARHPRAKIDFKIEDVYSNISDSLGDDRTAIDLIFEALKIQNVEPKVIPMRGGTDGSALSARGVLTPNYFTGALNFHSRFEFLPLSSFEKSYLVSESICRLVGQK
>NZ_CP048621.1|WP_163762065.1|2856203_2857757_-|AbgT-family-transporter
MTTNTLPKKKGFLNRVERIGNVMPDVTMLFIYALIICWFLSYLLSFVDFNYYHPVSKEKITVINMFNYEEIILFITAAVKNFINFPPLGITIVATLGIGIAESSGFINTALKKMLSFITPKMLTPTVVFVGIVSHIASDSAYVILMPVAAMMFYASGRHPLAGIAAAFAGLAGGFTASYTPSIIDPIMQSFTQDAAQMIAPGYSVNVLCNYFFSLGGTFGVIFTCWFITEKIVEPWLNKNCPITTKDVDTDADQDLGKITPLENRAFRVSGLVVLALAAGLFALLWPENSLLRGPDGSLTSPKAPIMQIVVPLLFIFFALPGIVYGYMTKSFTSTKDVVKAMENITKSLIPFIVFAFFAAQFLYSFQHSNLGTLLALSGAELLRTLDMPSGLTVFGVILLTAILNIMITSATSKWAIMAPVLVPMLMAVGISPELTQAAFRVSDSAMNVSTPMFPFYPLILMYCQKYYKNAGIGTLCSMMIPFTVGLLITLTATLYLFWAFDIPIGFDSGYTWQPTP
>NZ_CP048621.1|WP_014658103.1|2858051_2858468_-|phosphate-starvation-inducible-protein-PsiE
MNSMRNMRHASNIAWVLQWVLNIGLIALAIVLVFFLAKETYTMASLMFSGQKEATAYELLEGIVIYFLYFEFIALITKYFLSGYHFPLRYFIYIGITAVIRLIIVDHSDPLTTLLHSAAILVLVVALYIANTEKLKRE
>NZ_CP048621.1|WP_004918784.1|2858676_2859081_-|GFA-family-protein
MYQGQCLCGAVKISTHQPIDKISVCHCGMCQRWNGGPGFSVDCHDDVVIEGEEAVTRFASSQWGERAFCQRCGTHLFYHLHSPSSYYVSAALFEESQHAEMAMQIFVESKPKYYNFIEKTPMLTEQDIMKLMAK
>NZ_CP048621.1|WP_014658102.1|2859154_2859421_-|hypothetical-protein
MRTRFFSKLFIAIALLTSASLFAEAAETVTSYEQVNVKIEHPLKQNKMQDLGDIESMREQAEVRRVELTETTTDRRFNGRQFRIGDKQ
>NZ_CP048621.1|WP_004918779.1|2859622_2861095_-|DUF3999-family-protein
MKLTKSKGKWLTFVYLSFSFLLSSFVHAQEQKALTPYDFYQGIELKYSSDNSSFAWLELPSEAYINSAYPQTLQDVRVFNGTGQEVPSALFYDTEERRKISQVSFALQRLIIRADQVNSKEETHDDQQYLLIETQPSKLTRIELPAMQQAKDAVYQSYLLTRQNNNQEDFPIQTLSLQWMNNQQDWQGKVFIYASDNKQDWVNISAYQPVMSLNSNSGGIYSNTIKLLEGHYVALRAPYLMVIIVAAKETKIPDLTMAQGTSMVVHSTRRQETCHFITNNEGVSLNQLIYRLPSPQPLSAIVIQLRQANRVLPLHIEYTSTSGEEWLPLTNIVAYNQIQNGQEIRNPELVLNDLMVKKLRITALKGSWDDKPPYIEGKRDAVNLMFNVQGASPYLLVWGSQLAGIDNISYQELLGQPLTIDELMHRYPKLYVPEEIIELGGEEQLTSNDFVINEFDWMTITLWVLLGVGIIVLLYFCWYLLKEVNAKSSE
>NZ_CP048621.1|WP_014658101.1|2861081_2863871_-|DUF2339-domain-containing-protein
MDGLILIGLIIAILAAVSPILAIIAIVFVQRVKYQLFQQNQRILSLEQTLKRYQDREINQQTELSPPETIVASEKPQQYQSASEELSHYSNELEPLPTAPPVLNSQVTEEVPQRQFQPTVDVNRVAQSSNNVGHPSNNKVSGQNNEVVPLFSHFFSWIWKGNPLAKIGILLLFFGIAYLLKFSIQNNMLSPQVRLIASAVACLALLGVGWYLRHKKSLFALILQGGSIGCFYITVFAAFKLYTMLPYSMAFVAMILICAASILLALLQRAISLAVLASLGGYLAPILLSTGGGNHILLFSYYLMLSIAILVISVWQAWRPLNLVGMFMTYAVALLWGVQYYQIDYYVSSQLFLIANLIVFNVLTQLFALRYPHEKQLVVDYTLLLVPPFISMAMQCAISWQISFAPAFSALLLGLLYLLAGLRIHKRYAVVGKNLALGNIIIGIGFVTLAIPLALTYEWTSILWSVEGLLLLYYGFSQQNKKLIVIGPWLISVSALILLAGFSFNIWSRTSTYLVPVLLAACFSAGAIFHVKRGTSENYKVLSYAFLILGLMIWIVWLPVITDILSWSGESESFIIMALVIISAWLWRMLAIKTDWVPLLLCQSFIWLIGYYYLALDFINDQNPMGRGDGSLIWPVMLGSSILFVIHAQKARNIWLQRILHGATFWLILAFIATQVNWFVAILPWGMNELGYFIYVMAITLTILVMYWLQSQKMPPMKRNGIIYWYSFLPVIVVLIGLSFIANFEDGKLTFWNYVPLINPLDEAGLFSIASLLLMRRGLIQKLKKIREFDLWIIRGLGFSAIVLSGVWFNGIIIRIISDFAEINWNVDALFNSRLVQTVLSISWSLVALGFMIFASIKQNRMSWFLGAGIFACVIAKLFLVDIYGQDGLSRAISFIVVAVLILVVGYFSPLPPKTAQHKGTNEVEDEAN

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Crispr_ID: NZ_CP048621_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP048621_6

2922514-2922902

TypeI-F

I-F

Consensus_repeat	Method
GTTCACTGCCGCATAGGCAGCTTAGAAA	PILER-CR
TTTCTAAGCTGCCTATACGGCAGTGAAC	CRISPRCasFinder
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CRT

6 spacers

cas6f,cas7f,cas5f,cas8f,cas3-cas2,cas1

The CRISPR arrays of NZ_CP048621_6

>merge|NZ_CP048621|6|2922514-2922902|PILER-CR,CRISPRCasFinder,CRT
TTTCTAAGCTGCCTATACGGCAGTGAACTCGGTTTCGCCTTGTTCAACACGAACAACAACTTTCTAAGCTGCCTATACGGCAGTGAACGGCGAGACTCAGTGCATGAAGAGGTCCAGCAATTTCTAAGCTGCCTATGCGGCAGTGAACTTCTTGATGACACTCCAATAGCAAATGCGGACTTTCTAAGCTGCCTATGCGGCAGTGAACATGTTAGACGGATATCACTATATGTAAATCGTTTTCTAAGCTGCCTATGCGGCAGTGAACGTAGCGTAACTTTGCGTCAATCACTTCCGTGATTTTCTAAGCTGCCTATGCGGCAGTGAACCAAATGAAGGCTTGAAAAAATAATCTTTGTCATTTCTAAGCTGCCTATGCGGCAGTGAAC

>NZ_CP048621|6|6|2922514-2922902|PILER-CR
TTTCTAAGCTGCCTATACGGCAGTGAAC	TCGGTTTCGCCTTGTTCAACACGAACAACAAC
TTTCTAAGCTGCCTATACGGCAGTGAAC	GGCGAGACTCAGTGCATGAAGAGGTCCAGCAA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TTCTTGATGACACTCCAATAGCAAATGCGGAC
TTTCTAAGCTGCCTATGCGGCAGTGAAC	ATGTTAGACGGATATCACTATATGTAAATCGT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	GTAGCGTAACTTTGCGTCAATCACTTCCGTGAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CAAATGAAGGCTTGAAAAAATAATCTTTGTCA
TTTCTAAGCTGCCTATGCGGCAGTGAAC

>NZ_CP048621|6|5|2922514-2922902|CRISPRCasFinder
TTTCTAAGCTGCCTATACGGCAGTGAAC	TCGGTTTCGCCTTGTTCAACACGAACAACAAC
TTTCTAAGCTGCCTATACGGCAGTGAAC	GGCGAGACTCAGTGCATGAAGAGGTCCAGCAA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TTCTTGATGACACTCCAATAGCAAATGCGGAC
TTTCTAAGCTGCCTATGCGGCAGTGAAC	ATGTTAGACGGATATCACTATATGTAAATCGT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	GTAGCGTAACTTTGCGTCAATCACTTCCGTGAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CAAATGAAGGCTTGAAAAAATAATCTTTGTCA
TTTCTAAGCTGCCTATGCGGCAGTGAAC

>NZ_CP048621|6|5|2922514-2922902|CRT
TTTCTAAGCTGCCTATACGGCAGTGAAC	TCGGTTTCGCCTTGTTCAACACGAACAACAAC
TTTCTAAGCTGCCTATACGGCAGTGAAC	GGCGAGACTCAGTGCATGAAGAGGTCCAGCAA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TTCTTGATGACACTCCAATAGCAAATGCGGAC
TTTCTAAGCTGCCTATGCGGCAGTGAAC	ATGTTAGACGGATATCACTATATGTAAATCGT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	GTAGCGTAACTTTGCGTCAATCACTTCCGTGAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CAAATGAAGGCTTGAAAAAATAATCTTTGTCA
TTTCTAAGCTGCCTATGCGGCAGTGAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP048621.1\|WP_036967295.1\|2932960_2933353_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048621.1\|WP_099659349.1\|2932592_2932964_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048621.1\|WP_104873394.1\|2930625_2931603_-\|type-I-F-CRISPR-associated-endonuclease-Cas1	cas1	cd09718_cas1_CAS-I-F	gnl\|CDD\|132676
NZ_CP048621.1\|WP_004918654.1\|2920291_2921074_+\|flagellar-type-III-secretion-system-protein-FliR	unknown	unknown	gnl\|CDD\|235568
NZ_CP048621.1\|WP_104873396.1\|2923686_2924712_-\|type-I-F-CRISPR-associated-protein-Csy3	cas7f	pfam09615_cas7f_CAS-I-F	gnl\|CDD\|378222
NZ_CP048621.1\|WP_004918676.1\|2914925_2915369_+\|flagella-biosynthesis-chaperone-FliJ	unknown	unknown	gnl\|CDD\|235563
NZ_CP048621.1\|WP_004918642.1\|2924714_2925662_-\|type-I-F-CRISPR-associated-protein-Csy2	cas5f	pfam09614_cas5f_CAS-I-F	gnl\|CDD\|378221
NZ_CP048621.1\|WP_004918638.1\|2927080_2930629_-\|type-I-F-CRISPR-associated-helicase-Cas3	cas3-cas2	cas3-cas2-CAS-I-F	gnl\|CDD\|274201
NZ_CP048621.1\|WP_150376673.1\|2925658_2926930_-\|type-I-F-CRISPR-associated-protein-Csy1	cas8f	pfam09611_cas8f_CAS-I-F	gnl\|CDD\|378220
NZ_CP048621.1\|WP_004918680.1\|2913550_2914915_+\|flagellum-specific-ATP-synthase-FliI	unknown	unknown	gnl\|CDD\|181182
NZ_CP048621.1\|WP_163762069.1\|2933345_2934209_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048621.1\|WP_004918662.1\|2918825_2919254_+\|flagellar-biosynthetic-protein-FliO	unknown	unknown	gnl\|CDD\|183160
NZ_CP048621.1\|WP_163762070.1\|2934353_2935088_-\|porin-family-protein	unknown	unknown	gnl\|CDD\|226163
NZ_CP048621.1\|WP_014658072.1\|2919266_2920010_+\|flagellar-type-III-secretion-system-pore-protein-FliP	unknown	unknown	gnl\|CDD\|235566
NZ_CP048621.1\|WP_004918656.1\|2920019_2920289_+\|flagellar-biosynthesis-protein-FliQ	unknown	unknown	gnl\|CDD\|235567
NZ_CP048621.1\|WP_004918665.1\|2918384_2918801_+\|flagellar-motor-switch-protein-FliN	unknown	unknown	gnl\|CDD\|181183
NZ_CP048621.1\|WP_004918672.1\|2916896_2917379_+\|flagellar-basal-body-associated-protein-FliL	unknown	unknown	gnl\|CDD\|235909
NZ_CP048621.1\|WP_104873397.1\|2915369_2916731_+\|flagellar-hook-length-control-protein-FliK	unknown	unknown	gnl\|CDD\|236652
NZ_CP048621.1\|WP_004918669.1\|2917384_2918392_+\|flagellar-motor-switch-protein-FliM	unknown	unknown	gnl\|CDD\|235849
NZ_CP048621.1\|WP_004918644.1\|2923042_2923678_-\|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	cas6f	cd09739_cas6f_CAS-I-F:CAS-IV	gnl\|CDD\|187870

Protein	Function_ID	Function_description	E-value
NZ_CP048621.1\|WP_104873394.1\|2930625_2931603_-\|type-I-F-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|132676	TIGR03637, cas1_YPEST, CRISPR-associated endonuclease Cas1, subtype I-F/YPEST. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the YPEST subtype of CRISPR/Cas system.	4.00843e-177
NZ_CP048621.1\|WP_004918654.1\|2920291_2921074_+\|flagellar-type-III-secretion-system-protein-FliR	gnl\|CDD\|235568	PRK05701, fliR, flagellar type III secretion system protein FliR.	1.64892e-68
NZ_CP048621.1\|WP_104873396.1\|2923686_2924712_-\|type-I-F-CRISPR-associated-protein-Csy3	gnl\|CDD\|378222	pfam09615, Cas_Csy3, CRISPR-associated protein (Cas_Csy3). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This entry, typified by YPO2463 of Yersinia pestis, is a CRISPR-associated (Cas) entry strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy3, for CRISPR/Cas Subtype Ypest protein 3.	0
NZ_CP048621.1\|WP_004918676.1\|2914925_2915369_+\|flagella-biosynthesis-chaperone-FliJ	gnl\|CDD\|235563	PRK05689, fliJ, flagella biosynthesis chaperone FliJ.	7.31435e-35
NZ_CP048621.1\|WP_004918642.1\|2924714_2925662_-\|type-I-F-CRISPR-associated-protein-Csy2	gnl\|CDD\|378221	pfam09614, Cas_Csy2, CRISPR-associated protein (Cas_Csy2). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This entry, typified by YPO2464 of Yersinia pestis, is a CRISPR-associated (Cas) entry strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy2, for CRISPR/Cas Subtype Ypest protein 2.	3.56167e-132
NZ_CP048621.1\|WP_004918638.1\|2927080_2930629_-\|type-I-F-CRISPR-associated-helicase-Cas3	gnl\|CDD\|274201	TIGR02562, conserved_hypothetical_protein, CRISPR-associated helicase Cas3, subtype I-F/YPEST. The helicase in many CRISPR-associated (cas) gene clusters is designated Cas3, and most Cas3 proteins are described by model TIGR01587. Members of this family are considerably larger, show a number of motifs in common with TIGR01587 sequences, and replace Cas3 in some CRISPR/cas loci in a number of Proteobacteria, including Yersinia pestis, Chromobacterium violaceum, Erwinia carotovora subsp. atroseptica SCRI1043, Photorhabdus luminescens subsp. laumondii TTO1, Legionella pneumophila, etc.	0
NZ_CP048621.1\|WP_150376673.1\|2925658_2926930_-\|type-I-F-CRISPR-associated-protein-Csy1	gnl\|CDD\|378220	pfam09611, Cas_Csy1, CRISPR-associated protein (Cas_Csy1). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This entry, typified by YPO2465 of Yersinia pestis, is a CRISPR-associated (Cas) entry strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy1, for CRISPR/Cas Subtype Ypest protein 1.	1.78279e-121
NZ_CP048621.1\|WP_004918680.1\|2913550_2914915_+\|flagellum-specific-ATP-synthase-FliI	gnl\|CDD\|181182	PRK07960, fliI, flagellum-specific ATP synthase FliI.	0
NZ_CP048621.1\|WP_004918662.1\|2918825_2919254_+\|flagellar-biosynthetic-protein-FliO	gnl\|CDD\|183160	PRK11486, PRK11486, flagellar type III secretion system protein FliO.	1.92193e-30
NZ_CP048621.1\|WP_163762070.1\|2934353_2935088_-\|porin-family-protein	gnl\|CDD\|226163	COG3637, COG3637, Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane].	1.6838e-18
NZ_CP048621.1\|WP_014658072.1\|2919266_2920010_+\|flagellar-type-III-secretion-system-pore-protein-FliP	gnl\|CDD\|235566	PRK05699, fliP, flagellar biosynthesis protein FliP; Reviewed.	6.0386e-124
NZ_CP048621.1\|WP_004918656.1\|2920019_2920289_+\|flagellar-biosynthesis-protein-FliQ	gnl\|CDD\|235567	PRK05700, fliQ, flagellar type III secretion system protein FliQ.	7.28415e-33
NZ_CP048621.1\|WP_004918665.1\|2918384_2918801_+\|flagellar-motor-switch-protein-FliN	gnl\|CDD\|181183	PRK07963, fliN, flagellar motor switch protein FliN; Validated.	1.57005e-76
NZ_CP048621.1\|WP_004918672.1\|2916896_2917379_+\|flagellar-basal-body-associated-protein-FliL	gnl\|CDD\|235909	PRK07021, fliL, flagellar basal body-associated protein FliL; Reviewed.	4.92257e-60
NZ_CP048621.1\|WP_104873397.1\|2915369_2916731_+\|flagellar-hook-length-control-protein-FliK	gnl\|CDD\|236652	PRK10118, PRK10118, flagellar hook length control protein FliK.	1.6072e-27
NZ_CP048621.1\|WP_004918669.1\|2917384_2918392_+\|flagellar-motor-switch-protein-FliM	gnl\|CDD\|235849	PRK06666, fliM, flagellar motor switch protein FliM; Validated.	9.30166e-164
NZ_CP048621.1\|WP_004918644.1\|2923042_2923678_-\|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	gnl\|CDD\|187870	cd09739, Cas6_I-F, CRISPR/Cas system-associated RAMP superfamily protein Cas6f. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6f is an endoribonuclease that generates crRNA; This family is specific for CRISPR/Cas system I-F subtype; Possesses RRM fold; also known as Csy4 family.	3.97577e-53

>NZ_CP048621.1|WP_004918654.1|2920291_2921074_+|flagellar-type-III-secretion-system-protein-FliR
MLTITSETLTLWLSQGFYPFIRLLALFGTAPFFNEKQSITKVRVILAFFIILIVSPQLPVVNIPLFSAMGLWVIVQQIVIGVAIGLTMQMAFAAVRHAGEVIGLQMGLSFATFFDPTGGPNMPILGRILNLIMLLLFLSFDGHLWLIYILIHSFELIPIQVSPLSRDGFWSLAQFASSIFINGLMLALPFITLFLILNLALGILNRMTPQLSVFVVGFPLTLTIGISMLGLIISILPRYSERLIHQAFEQLSLMFGLLGG
>NZ_CP048621.1|WP_004918656.1|2920019_2920289_+|flagellar-biosynthesis-protein-FliQ
MTPESVMALGTEAMKIALMLAAPLLLAALVAGLTISLLQAATQVNEMTLSFIPKILSVIAVIIIAGPWMLNLLLDYMRTLFSNLPFIIG
>NZ_CP048621.1|WP_014658072.1|2919266_2920010_+|flagellar-type-III-secretion-system-pore-protein-FliP
MFSVKSPAMIASLLLMLPMQALASLPPVISRTLPDGGQSWSLPVQTLLFLTLLGFIPALLLMMTSFTRIIIVLGLLRNALGTPSAPPNQVLLGLALFLTFFVMSPVADQAYREAYQPFSEDKISLETALERGTAPFRTFMLGQTRESDLALFARIAKVGEIQEAKDVPMRILVPAFITSELKTAFQIGFTIFIPFLIIDLVVASVLMALGMMMVPPATVSLPFKLMLFVLVDGWQLLLGSLSQSFFN
>NZ_CP048621.1|WP_004918662.1|2918825_2919254_+|flagellar-biosynthetic-protein-FliO
MKTTPFISQTEQPSSQISPAISNSDSLVQVSGALGGIILLILAGAWLVKKLGFAPRNLGKPSLIKVKSSCSLGNKERVVVVEMNNEWLVLGVTAQSVNLLHQCPAKNETALTSVTEPLTFQSILKKKQDAANHAASNLSNYN
>NZ_CP048621.1|WP_004918665.1|2918384_2918801_+|flagellar-motor-switch-protein-FliN
MSEAKNSPDASTNHDSEDLWAEALEQQKKAESASAGAQAFANLDGQNALNQLSDINLIMDIPVRLSVELGRTKMTIKKLLSLSQGSVVSLDGLAGEPLDILINGYLIAQGEVVVVSDNYGIRITDIITPSERMRRLSR
>NZ_CP048621.1|WP_004918669.1|2917384_2918392_+|flagellar-motor-switch-protein-FliM
MSDNILSQAEIDALLNDDAPSSNESATQPKDKEQVRPYDPNTQRRVIRERMQSLEIINERFARQFRMGLFNMLRRSPDITVGGIKIEPYHEFARNLPVPTNLNLIHMPPLRGTALFTFEPALVYIAVDNLFGGDGRFPVRSEGKEFTNTEQRIIHRMLKLALSAYRDAWRPIADIDVEYVRSEMQVKFTNITTSPNDIVVTTPFLVEIGNTIGEFSICIPIAMIEPLRERLINPPVEQGHQENEAWVSNLVTQVKRSELELVANFVDIPLRISRLLQLQKGDVIPIEKPDRLIVSVDGVPVLTSQYGTQNGQYALRVEHLINPVLNTLDEESTNE
>NZ_CP048621.1|WP_004918672.1|2916896_2917379_+|flagellar-basal-body-associated-protein-FliL
MSSSSNTSKNSNKGLLVLFALLAIAGAGFGGYTWWTTQQTANSVNEEEKSPKLSQPIFMDLEPFTVNLPGLNESPDRVLYINITLRLANEKSRKQLHDFLPEVRSRLLLLLSEQKPKALSTHDGKLQLMQAIKKTLSPTVIPGENDQEITDVLFTTFILR
>NZ_CP048621.1|WP_104873397.1|2915369_2916731_+|flagellar-hook-length-control-protein-FliK
MDVNNTGSPAITAANGAKNGHTQPNQSRADDNQEVVVPFQAALESQQPTPQKASTSEPTMDKQANQKPTSADERLTTKAHEPSTGKEKEQAEQAIEQLNYSRHLRNGSEQPALQSQLLAQSDAVEQVWLANLKNAVDQQTLSSATTKFADGQRAALVPFAQKTQPLNDSLVAMATMDEPIDLSAQMQLAGEEESPSLGAFIKNEREPRKDQPLFSLNEGRESLTKNLSSDFMPLNKKLADKEAPSSIVPTFATADNGALIKGAFTPTTGSDAIQMAPSSPTQTVSLTPLPNSSQIVSTNVPVIPMQPGVPLGSEAWQQQLNQHMLFFSRQGVSHAQIRLHPEELGSLNVHLRIEDNQAVMHFVSPHSQVRAAMETMMPILRNALQESGIHLAQGSVGQDNFSDQSNADTHSEQGHEKNLYGGQTLSSVTSTEMAAVSPTTSTIRTRGGIDTFA
>NZ_CP048621.1|WP_004918676.1|2914925_2915369_+|flagella-biosynthesis-chaperone-FliJ
MSKNNALDTLLSLAVEASEEAAKVLAQVRQTQVQMTQQLNMLENYQAEYRQKLNQTLHSGIDADKWQNYQQFLVTLELTIEQQQQQLSLWEQRVSEANRHWQEKQQRVNAFDTLIQRAEQTKNQRLNRLEQKQMDEYAQRAMLRRNQ
>NZ_CP048621.1|WP_004918680.1|2913550_2914915_+|flagellum-specific-ATP-synthase-FliI
MTVRMSRWIAALEGFESRMKGIPMIRRYGRLTKITGLVMEAEGIKMPLGATCFVERAINDRHDEVVCEVVGFNGPRMLLMPLADLEGIAPGARVYAQTNGDDGQTSRLLPLGDELLGRILDAQGTPLDGKGPLDAKQRAPLITPPINPLERTPIHSVLDVGVRAINALLTVGRGQRMGLFAGSGVGKSVLLGMMARFTQADIIVVGLIGERGREVKDFIENILGAEGLKRAVVVAAPADVSPLLRMQGASYATRIAEYFRDLGKNVLLIMDSLTRYSMAQREIALAIGEPPATKGYPPSVFAKLPALVERAGNGKNGGSITAFYTVLTEGDDQQDPIADSARAILDGHIVLSRSLAESGHYPAIDIEASISRAMTELIDKQHYRQIQRFKQLTSSYQRNRDLINVGAYATGSDPLLDMAIQYYPRMSKFLQQDIDERCDYQSACEQLVHAVPNE
>NZ_CP048621.1|WP_004918644.1|2923042_2923678_-|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4
MDYYQEITLLPDSTIPLDFLWQKVYQQIHIALVENKSEAGDSEVAVAFPEYGSVGFRLGKKLRLLAKTEKTLTQLNISHWLMRLADYVHIKSIQAVPEHATPISYVRQHVKGAKRLELDRYKKAQLYSVKSGQPIEVCLSAIKEPQTRSRLPFIWMESQQTKSKTEGDGHRPFPLFIRCVAAKEAKAGTFNCYGLSQSMGKGEEVATVPHF
>NZ_CP048621.1|WP_104873396.1|2923686_2924712_-|type-I-F-CRISPR-associated-protein-Csy3
MAKNNDVASVLAFEKKLVPSDGYFYGTSWDHKSQCTPLVLQEKSVRGTISNRLKGPVKNDPLKLNAEVEKANLQTVDACALGTQQDTLKHQFTLKILGGVETPSACNNASFKESYTKAAKEYIAREGFRELGRRYAHNIANARFLWRNRVGAEKIEVEVRVLNKGQEQQWTFDATQYSIRSFEKQDDKVNELGAKIAAALANSEGALLLEITTYAQLGQSQEVYPSEELVLDKGKGDKSKILYHVNGHAAMHSQKIGNALRSIDTWYPDYNDEVNSAGAIAIEPYGAVTNLGRAYRTPSDKQDFYTHFDKWARGEKLARLEDEHYVMAVLVRGGVFGESDK
>NZ_CP048621.1|WP_004918642.1|2924714_2925662_-|type-I-F-CRISPR-associated-protein-Csy2
MNNSMNLIKLSHLKVHNANALSSPFTIGFPAMTAWLGFMHALELKLRKIGFLELQLESIAVISHECNLQTYKGPSDFVSSIVGTGNPLDKEGNRSAFIEEARCHLDVSLLIEFSDRNDEYGNVLTDKSIVDRIYELIPMMKLAGGDILSVDLPQMHYLPANDDMGKYRRSLFNSLMPGYALIERRDLMVSAMEDGQDAMDALLDYVTVHNQCVEVDIQNESKNKHYEWKVQRKTAGWIVPIATGYQGISPLGQAKNQRDPNVPHRFAESLVTLGQFVMVNKIGHPNEILWKYSNNLENSLYLCQQVESKYFTSGE
>NZ_CP048621.1|WP_150376673.1|2925658_2926930_-|type-I-F-CRISPR-associated-protein-Csy1
MLDPAIEAFFAERKEGWLKKNLKASMSEAEVHQIEQQCEDTFALSQWLPNAAKRAGQISLSTHPCTFSHPSARKNKNGYVSAIIANAKQANDGFLRSSNVAVEPDALGNAAALDVYKFLTLQMQDGATLLAHIEAETQLAKTLLTLNNESYQEIRNGFLAMSATDDSVVTSSKIKQVYFPVWLDDEDYHLLSILTPSGLLFEMRRRIDDIRFSEQTKTLRDLKRKGEYSEVGFKEIYGLTTIGFGGTKPQNISVLNNQNAGKAHLLLSLPPVLNIRETRLPKTNFFTDAINPWHAKETFQAFHGLINLPKDKRGNRFIEYRDNRIQEYVDYIIVMMWKVRRALEQENITLPNKISNYQKTWLFPDNQEQRDNTDDWLEILIPEIARQFIAGYKVVNGKKALFLGNDEFNAIVDVVARYKELLR
>NZ_CP048621.1|WP_004918638.1|2927080_2930629_-|type-I-F-CRISPR-associated-helicase-Cas3
MMVTFVSQCEKHALKRTRRVLDAFANRIGDNTWQTLITEDGLQTVKKMLRQSASRNTAVSCHWIRSRSRSQLLWVVGNRNKFNSQGHVPVNRTEKSFLGSEFENDWKYLSLIAAVARLAALFHDWGKASRLFQDKLNPAVKMPFKGDPVRHEWVSSILFSSLVKIHSAEGSEEKWLDALIHQEWDESQLQQCVNDNCLASNPLAELPDAAALLTWLILTHHKLPFLDEQELCNWQDKAINLHTQLLAKIKQSWGYRNGNDDAQFQQRIKMCFEFPNGLLSNSKAWVQAVQQAATDLKNQLPLFQQAMADGSWRVIAHYARLCLMLGDHNYSSQGNDPQWHSDIALYANTHKIRNINNIPQVTFKQKLDEHLVKVAETARDIAETLPYFESEPPFASDVPKLAYDKNSTGKFSWQEDAVNSIYQYRKERNDDIKGYFIVNMASTGCGKTRANAKIMQALSEDKQSLRYILALGLRTLTLQTGDEYKDQNKIGLGERDLAVLIGSKAVAQLHQNAKENENASEASNDTSSHQTNSESNDLKPHQTGSESQEMLFDENEEMLRWDENKWSGILPEEVLSTVLTREKDRALLYAPVLACTIDHIIGATETIRGGRYILPCLRLMSSDLVIDEVDDFIEADSAAIARLIHMVGLLGRKVMISSATITPDTALAYFHAYQSGWHAHAKSRQQSLEIGCMWIDEGEYDPVKEKCKSSTLAATLVANDENTPYFYQQYHGKFIDKRAKVLGQQPARRKALIVPTPKDNTQESQQCYFNHILNAVLTQHHYHAFLDKRTGIQVSFGVIRVANILPCIDLTRFLLECECPDEVEIRTMAYHSQQVLLLRHEQEQHLDSVLKRKEKSGEEPDALNDAIIRQHLAQVSAEGKAKHLIFILVATPVEEVGRDHDFDWAVVEPSSWRSIIQIAGRVRRHREGEVAQPNMALLQYNLKGFEEGNDNPFSRPGYENRYINLGLSTHDLYELVDEQQLNKSVDAIPRIQKQANYESKKHTNLACLEHAAIKYTFKIEHIFPPKRAENSATSSRRTTRRSNHQTIPSNAASHIWGYTHGNWWMTAISQQIASFRSGAPSFRLVLEILPRGEMQFSEYHRENGWVNVGAQNGIHFIEFPESMKKRLWLVRDYAKSLESQTEEAEQITSLSRFYGEITFLKCLNVHDGYRYDDQMGVYPIKR
>NZ_CP048621.1|WP_104873394.1|2930625_2931603_-|type-I-F-CRISPR-associated-endonuclease-Cas1
MDDFSPADLKTILHSKRANMYYLEHCRVMQKDGRVLYFTEAKNENLYFNIPIANTTVLLLGTGTSITQAAMRMLSQAGVLVGFCGGGGTPLYMSTEVEWLTPQSEYRPTEYLQGWMRFWFDDKKRLAAAKTLQRSRISYLQKTWQSSRELQNEGFIYNDTLIQNALETFHTRTEAADDPQTLLLTEAQLTKALYKYAANNTGQKNFTRQHQAMDKANAFLNHGNYLAYGLAASCLWVLGIPHGFAVMHGKTRRGALVFDVADLIKDAIVLPWSFICAKEGASEQEFRQQILQSFIDNHALDFLFDTVKTIALHTGSEQQIQEPKL
>NZ_CP048621.1|WP_099659349.1|2932592_2932964_-|hypothetical-protein
MKNRTLNSLPFVGIIAVVTLGIYYGKQTKPTYRDCVELSSSPANRLQIYEQPDRTSKSINYQPTSGKEQFWVAKRTADEQWVQLYHAITLFDDLPESAKLGWVSAKNINTLGIFECMTKNQNL
>NZ_CP048621.1|WP_036967295.1|2932960_2933353_-|hypothetical-protein
MTKYVFIFMVFCLNFTASAFNTNVFDTAIDKSGFTPMCNNQAIADKDCRVDDYLEGRYVVTSTVNLGAKCAFVIAEVIDSQTNQLFSTSTGDCEDGPLDTYYRLSRINKKVWLDAYSQGKHIDHVEVIFQ
>NZ_CP048621.1|WP_163762069.1|2933345_2934209_-|hypothetical-protein
MNSINHIRLGVERIFFIISLVLVFGFTVIIANHYNIDSFIGKPLMYLLYYLIAMLAPLLISQILLWVIYGFMGIPFRLMLTRKILAFVFAFIASLCVIYLLLIGIIPFMVFDHALIFILYEYFFIFLLFACLIGLSAGVIVYIHTVKNVSHPFEYPHPIFRLMTFLALYLVIMNALAIGIVNQINLNIMVILAGTIAGYVGYWGYGFLQQYTATRSRKLRITLSTIISLVILALLVLLNVLLPNRLNMFGLFLLFFIELAIAITLGRLTYQKNNHQKDGSTMRINHD
>NZ_CP048621.1|WP_163762070.1|2934353_2935088_-|porin-family-protein
MKKAFIIPALMGCISLPAFANTDDSKTGLYITGKMGASIVQMSGQQFVYSGYADAGDNGTKNGDSHRTGVFGGGLALGYDFSNQFDIPVRAELEFMARDKANSTYNIRDRVRNGVHQTRDIKNQIKLNTLMVNGYYDIKNSSNFTPYISVGLGYAAVDFKTTRADAYTPGLSLHDTHTHTTNNFAWSVGAGVNYAINDDWDMGLSYRYLDAGKADITTAVGDGENTSKIKVKANDIMLGLTYRF

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Crispr_ID: NZ_CP048621_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP048621_7

2974292-2974620

Orphan

I-F

Consensus_repeat	Method
GTTCACTGCCGTATAGGCAGCTTAGAAA	PILER-CR
TTTCTAAGCTGCCTATACGGCAGTGAAC	CRISPRCasFinder
TTTCTAAGCTGCCTATACGGCAGTGAAC	CRT

5 spacers

The CRISPR arrays of NZ_CP048621_7

>merge|NZ_CP048621|7|2974292-2974620|PILER-CR,CRISPRCasFinder,CRT
TTTCTAAGCTGCCCATACGGCAGTGAACGTCATAAACTTCTTTAGCTTTCGCTTGCTCTGTTTCTAAGCTGCCTATACGGCAGTGAACCCTTACTCGATAGCCTGGTGTATTCGTGATGATTTTCTAAGCTGCCTATACGGCAGTGAACGCACTAGCAGTCTTACCAGTACGCATCGTAGATTTCTAAGCTGCCTATACGGCAGTGAACAAAAGATGACAATGATAAATGCCATGTTTGCATTTCTAAGCTGCCTATACGGCAGTGAACTTGATGCAGATGGAATTCGGGTGCTGTTTAATTTTCTAAGCTGCCTATACGGCAGTGAAC

>NZ_CP048621|7|7|2974292-2974620|PILER-CR
TTTCTAAGCTGCCCATACGGCAGTGAAC	GTCATAAACTTCTTTAGCTTTCGCTTGCTCTG
TTTCTAAGCTGCCTATACGGCAGTGAAC	CCTTACTCGATAGCCTGGTGTATTCGTGATGAT
TTTCTAAGCTGCCTATACGGCAGTGAAC	GCACTAGCAGTCTTACCAGTACGCATCGTAGA
TTTCTAAGCTGCCTATACGGCAGTGAAC	AAAAGATGACAATGATAAATGCCATGTTTGCA
TTTCTAAGCTGCCTATACGGCAGTGAAC	TTGATGCAGATGGAATTCGGGTGCTGTTTAAT
TTTCTAAGCTGCCTATACGGCAGTGAAC

>NZ_CP048621|7|6|2974292-2974620|CRISPRCasFinder
TTTCTAAGCTGCCCATACGGCAGTGAAC	GTCATAAACTTCTTTAGCTTTCGCTTGCTCTG
TTTCTAAGCTGCCTATACGGCAGTGAAC	CCTTACTCGATAGCCTGGTGTATTCGTGATGAT
TTTCTAAGCTGCCTATACGGCAGTGAAC	GCACTAGCAGTCTTACCAGTACGCATCGTAGA
TTTCTAAGCTGCCTATACGGCAGTGAAC	AAAAGATGACAATGATAAATGCCATGTTTGCA
TTTCTAAGCTGCCTATACGGCAGTGAAC	TTGATGCAGATGGAATTCGGGTGCTGTTTAAT
TTTCTAAGCTGCCTATACGGCAGTGAAC

>NZ_CP048621|7|6|2974292-2974620|CRT
TTTCTAAGCTGCCCATACGGCAGTGAAC	GTCATAAACTTCTTTAGCTTTCGCTTGCTCTG
TTTCTAAGCTGCCTATACGGCAGTGAAC	CCTTACTCGATAGCCTGGTGTATTCGTGATGAT
TTTCTAAGCTGCCTATACGGCAGTGAAC	GCACTAGCAGTCTTACCAGTACGCATCGTAGA
TTTCTAAGCTGCCTATACGGCAGTGAAC	AAAAGATGACAATGATAAATGCCATGTTTGCA
TTTCTAAGCTGCCTATACGGCAGTGAAC	TTGATGCAGATGGAATTCGGGTGCTGTTTAAT
TTTCTAAGCTGCCTATACGGCAGTGAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP048621.1\|WP_163762085.1\|2961694_2962114_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048621.1\|WP_014658060.1\|2979850_2980582_-\|flagellar-basal-body-L-ring-protein-FlgH	unknown	unknown	gnl\|CDD\|234700
NZ_CP048621.1\|WP_163762089.1\|2967607_2968279_+\|inovirus-Gp2-family-protein	unknown	unknown	gnl\|CDD\|371695
NZ_CP048621.1\|WP_163762090.1\|2968803_2970636_+\|RNA-directed-DNA-polymerase	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|239569
NZ_CP048621.1\|WP_004918619.1\|2977725_2978706_-\|flagellar-assembly-peptidoglycan-hydrolase-FlgJ	unknown	unknown	gnl\|CDD\|235559
NZ_CP048621.1\|WP_163762084.1\|2961221_2961488_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375382
NZ_CP048621.1\|WP_014658062.1\|2975840_2977481_-\|flagellar-hook-associated-protein-FlgK	unknown	unknown	gnl\|CDD\|236165
NZ_CP048621.1\|WP_099659369.1\|2972093_2972648_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048621.1\|WP_099659368.1\|2971164_2972097_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048621.1\|WP_163762086.1\|2963458_2965462_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048621.1\|WP_014658063.1\|2974877_2975813_-\|flagellar-hook-filament-junction-protein-FlgL	unknown	unknown	gnl\|CDD\|181202
NZ_CP048621.1\|WP_104873393.1\|2980707_2981490_-\|flagellar-basal-body-rod-protein-FlgG	unknown	unknown	gnl\|CDD\|183687
NZ_CP048621.1\|WP_004918605.1\|2984383_2984788_-\|flagellar-basal-body-rod-protein-FlgC	unknown	unknown	gnl\|CDD\|235556
NZ_CP048621.1\|WP_014658061.1\|2978705_2979809_-\|flagellar-basal-body-P-ring-protein-FlgI	unknown	unknown	gnl\|CDD\|235399
NZ_CP048621.1\|WP_163762088.1\|2965808_2967302_+\|DUF3987-domain-containing-protein	unknown	unknown	gnl\|CDD\|379041
NZ_CP048621.1\|WP_004918610.1\|2981509_2982265_-\|flagellar-hook-basal-body-complex-protein	unknown	unknown	gnl\|CDD\|183642
NZ_CP048621.1\|WP_163762087.1\|2965548_2965791_+\|AlpA-family-phage-regulatory-protein	unknown	unknown	gnl\|CDD\|225848
NZ_CP048621.1\|WP_061064158.1\|2983531_2984371_-\|flagellar-basal-body-rod-modification-protein	unknown	unknown	gnl\|CDD\|235847
NZ_CP048621.1\|WP_072063271.1\|2972834_2974076_-\|integrase	unknown	unknown	gnl\|CDD\|170049
NZ_CP048621.1\|WP_004918608.1\|2982280_2983501_-\|flagellar-hook-protein-FlgE	unknown	unknown	gnl\|CDD\|235557

Protein	Function_ID	Function_description	E-value
NZ_CP048621.1\|WP_163762089.1\|2967607_2968279_+\|inovirus-Gp2-family-protein	gnl\|CDD\|371695	pfam11726, Inovirus_Gp2, Inovirus Gp2. Isoform G2P plays an essential role in viral DNA replication; it binds to the origin of replication and cleaves the dsDNA replicative form I (RFI) and becomes covalently bound to it via phosphotyrosine bond, generating the dsDNA replicative form II (RFII).	1.50939e-59
NZ_CP048621.1\|WP_163762090.1\|2968803_2970636_+\|RNA-directed-DNA-polymerase	gnl\|CDD\|239569	cd03487, RT_Bac_retron_II, RT_Bac_retron_II: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA branches out from a small ssRNA molecule via a 2'-5'phosphodiester linkage. Bacterial retron RTs produce cDNA corresponding to only a small portion of the retron genome.	2.62034e-68
NZ_CP048621.1\|WP_004918619.1\|2977725_2978706_-\|flagellar-assembly-peptidoglycan-hydrolase-FlgJ	gnl\|CDD\|235559	PRK05684, flgJ, flagellar assembly peptidoglycan hydrolase FlgJ.	5.3169e-144
NZ_CP048621.1\|WP_163762084.1\|2961221_2961488_-\|hypothetical-protein	gnl\|CDD\|375382	pfam17854, FtsK_alpha, FtsK alpha domain. FtsK is a DNA translocase that coordinates chromosome segregation and cell division in bacteria. In addition to its role as activator of XerCD site-specific recombination, FtsK can translocate double-stranded DNA (dsDNA) rapidly and directionally and reverse direction. FtsK can be split into three domains called alpha (this entry), beta and gamma. The alpha and beta domains contain the core ATPase machinery of the DNA translocase.	3.51241e-11
NZ_CP048621.1\|WP_014658062.1\|2975840_2977481_-\|flagellar-hook-associated-protein-FlgK	gnl\|CDD\|236165	PRK08147, flgK, flagellar hook-associated protein FlgK; Validated.	0
NZ_CP048621.1\|WP_014658063.1\|2974877_2975813_-\|flagellar-hook-filament-junction-protein-FlgL	gnl\|CDD\|181202	PRK08027, flgL, flagellar hook-filament junction protein FlgL.	5.50916e-99
NZ_CP048621.1\|WP_163762087.1\|2965548_2965791_+\|AlpA-family-phage-regulatory-protein	gnl\|CDD\|225848	COG3311, AlpA, Predicted transcriptional regulator [Transcription].	2.61442e-14
NZ_CP048621.1\|WP_104873393.1\|2980707_2981490_-\|flagellar-basal-body-rod-protein-FlgG	gnl\|CDD\|183687	PRK12693, flgG, flagellar basal body rod protein FlgG; Provisional.	3.01411e-153
NZ_CP048621.1\|WP_004918605.1\|2984383_2984788_-\|flagellar-basal-body-rod-protein-FlgC	gnl\|CDD\|235556	PRK05681, flgC, flagellar basal body rod protein FlgC; Reviewed.	2.38262e-72
NZ_CP048621.1\|WP_014658061.1\|2978705_2979809_-\|flagellar-basal-body-P-ring-protein-FlgI	gnl\|CDD\|235399	PRK05303, flgI, flagellar basal body P-ring protein FlgI.	0
NZ_CP048621.1\|WP_163762088.1\|2965808_2967302_+\|DUF3987-domain-containing-protein	gnl\|CDD\|379041	pfam13148, DUF3987, Protein of unknown function (DUF3987). A family of uncharacterized proteins found by clustering human gut metagenomic sequences.	2.75624e-68
NZ_CP048621.1\|WP_004918610.1\|2981509_2982265_-\|flagellar-hook-basal-body-complex-protein	gnl\|CDD\|183642	PRK12640, flgF, flagellar basal body rod protein FlgF; Reviewed.	2.0995e-111
NZ_CP048621.1\|WP_014658060.1\|2979850_2980582_-\|flagellar-basal-body-L-ring-protein-FlgH	gnl\|CDD\|234700	PRK00249, flgH, flagellar basal body L-ring protein FlgH.	8.44649e-98
NZ_CP048621.1\|WP_061064158.1\|2983531_2984371_-\|flagellar-basal-body-rod-modification-protein	gnl\|CDD\|235847	PRK06655, flgD, flagellar hook assembly protein FlgD.	1.0913e-46
NZ_CP048621.1\|WP_072063271.1\|2972834_2974076_-\|integrase	gnl\|CDD\|170049	PRK09692, PRK09692, integrase; Provisional.	0
NZ_CP048621.1\|WP_004918608.1\|2982280_2983501_-\|flagellar-hook-protein-FlgE	gnl\|CDD\|235557	PRK05682, flgE, flagellar hook protein FlgE; Validated.	2.17475e-153

>NZ_CP048621.1|WP_072063271.1|2972834_2974076_-|integrase
MARKTKPLTDTEIKAAKPQDKDYQLYDGDGLTLLIKSSGSKLWQFRYYRPYTKQRTKQSFGAYPAVTLSDARKLRAESRSLLAKDIDPQEYQKNQIRNSQEAKTNTFQLVAERWWEVKKSTVTEDYGNDIWRSLERDVFPAIGDISVTDIKAHILVQAIQPVQARGALETVRRLCQRINEVMIYAQNTGLIDAVPSINIGKAFEKPKKKNMPSIRPEQLPQLMQTMRTANIILPTRCLFMWQLLTISRPAEAAEARWDEINFETKEWKIPAARMKMNREHIVPLSDAALAILELMKPLSGNREFIFPSRIKPTQPMNSQTVNAALKRAGFGGVLVSHGLRSIASTALNEQGFPPDVIEAALAHVDKNEVRRAYNRSDYLEQRRPMMQWWADFIEEADKGSIIEGGIRGISLVG
>NZ_CP048621.1|WP_099659369.1|2972093_2972648_+|hypothetical-protein
MNKINIWQVLLKHYRTMTDQRGVTLRQDIFIHFFLPGIISVFICILYGTMKPSIAAVFVNFGAITTALLMSAVIMIYDQKQKTIFKISDIIENKKPTTNLPALETNKKVYEQLCHNVAYAILTSVILVIASVIISFFPEKKETLALLYFSIPAFMLSFIAYAAFFITVITFLMVIKRFSFILDN
>NZ_CP048621.1|WP_099659368.1|2971164_2972097_+|hypothetical-protein
MHSINFYSFRILTHKGSRQSKQLGALGLSNKKTAYEILKEYLTSHKDTPIEYGVSKTKISLERHKKLTFNDTKGLIHGYIKVGKYGESSEIKDIKLKTTQYTTKVDDVTLRERYVLIYLPDSLEEGIIAFHSSDNVSAKGTISDALVEYFKKKYQLEARINPLCHKKIPQYILDSEVKQIRALGYEAPSDIADSFGTNKTNVKTDLVIKYNQGYMGSFRDLQSKKISNVIEVIEDKCEEIKVTLQLGNRTVVFKYDTIIKKGISIELDDSTLKINASTGIPELKALHGVVHSLTNDILLEIHNGNKGVCI
>NZ_CP048621.1|WP_163762090.1|2968803_2970636_+|RNA-directed-DNA-polymerase
MNRLLLLKSAKTKPDLARILGVKPSALTHCLYVIKPENQYVQFEIPKRNGGKRIISAPSGMLKNLQSSLSDLLLDCLDEIIFLKFPDSEITRQKAKNSLFLKVKCSGSETKQPSLSHGFERKRSIITNAMMHLGKKHVFNIDLENFFGSFNFGRVRGFFIKNRNFLLEPEIATVIAKIACYNNELPQGSPCSPVISNLITHALDIKLAAVAAKHSCTYTRYADDITFSTRKENLPSSVAKSDNHTFVAGKVIRREIARSGFSINESKTRDQYKDSRQEVTGLVVNKKPNTKKEYWRLVRAQCNHLFNTGEFKETINGAEVTGNIHRLEGKLTFIDQVDHYNRLRQGEKLNPKYSLKKDAIKKSTRRYLHTSRETTFSKFLFYRWFYGNTKPTILTEGQTDNIYLKSAIWRLAVQFPKLATGRSATEPYKALTQFFKYNERTRYLLELFGGGDYLRDFVDSYKKLFNAYKAPKPSHPVIIFVDNDSGPNNLINTVKRVKGINIFPAAVDVDNIRQSEFVHIFCNLYLVLTPQGAGSSETDIEYFFSDTDRLREHKGKCFNTVAARDKVNDLSKEAFATHIVKTQKSIIDFSRFTHLLERIEKVIDHYNSIK
>NZ_CP048621.1|WP_163762089.1|2967607_2968279_+|inovirus-Gp2-family-protein
MSDYALTKTELDQLITIASDRYDSSISYYILRRLLAVVENTLEHHNRVFAIRVDLRFAQDSSPDAPDMPICFQRTDERAITRFIESLKSQLRAAHHRTGRSGTPALPYYAWVRERNESEYPHYHLVLLFNRDIYGYLGNYLQDDANNMATRIQRAWCSAIGLVYPDYAPLVNFPENPVFRFDRRDALARHSNYFDFLLRMTYLAKMNTKELIADFRNFGTSQV
>NZ_CP048621.1|WP_163762088.1|2965808_2967302_+|DUF3987-domain-containing-protein
MSQKNEELYLNIEKLPDYFQRMIEQVHIKTGAAAEIILPTLLSVMSLSCQDSFDIEPISGRKYPLSLYHVVLARSGCRKSTVYKLLTKAISEFEQQLEQDFYIEKDNYERSLVLWNIKFSALNKCYQKALNQGIKVNEALLNLEECLVQKPVAPIKKRLVINDSTSEGLAQELGDGYPVLSLMSDEAGELFESSLLRKTPLLNSLWCAEGKSVSRASRDNYVIKDCRFSLLLMVQPALFDSFMDKKGKKAKSSGFLARSLLVDLDQIQQLCEIKNVSHSTELSLADLSATLIKHLQKGIKRRENDEERHCITLAHDAQGAWNGYYQAVKKMMEPGGELHAYDDYASRFMEHASRIAGVMQMFMTPDSTVVTLETLESAVYITQWHLNHFIKKIDDFKEVSDAEKLLLWLAEHLVSNKSYDFRRNDIIKNGPYSLRRSDRLRPALEKLQQEAKVQLFEKNGINYVKFTGARMTPEELAERLNIPLSSRGVFILNNSPR
>NZ_CP048621.1|WP_163762087.1|2965548_2965791_+|AlpA-family-phage-regulatory-protein
MENQMHHLNENVNQSNLPLRILRMTELTVLLGISRSSIYEKLNPRSKYYDPDFPKPIKLGASSVGWQYASVEKWLTSRMV
>NZ_CP048621.1|WP_163762086.1|2963458_2965462_-|hypothetical-protein
MYTHIFANIMLTAYDITVLNKERIEKTNTKERKNKNKKYKTLNLANQRKIENFSLHQDFFAKTGNLKTQEYGDDNINTKETYQKLINIIDSKAVFTQTERQMFFYKYEQLYNALIAQYVVSNLEKKEILRKYTKATIPAIVALDMYKTLSLSVDKEQLHFYSHIHHFILSEYYDNHHNNLESLCKGVRAYLKYYIKTLAFNPIVNLFEITTSINNIRTSSFTTICNIDTIIDACKKEASEIGKPHDTQFEQLRVAYTSLSVLLAFQKITHLLTPLVSNYKKLLEDKLEAPDPLFYLERYLYQNVENDPIFLGENALYEYIEVLISHEKIDIPSCEDDCDCGQGPECECQCIPSYFYGILNILENFIFENKSHLPLPTLVPSINLSEFSLKKISIFELSSYLDELCDEVPSLKLYKEIPYILELLYANELDNIREVINEISFEEFPLGFFTSTLAIINLALKIKFEPKSIRYGSLLSYINPILTNQGVYTEYLIITPDIKNPTQSVSDIEENPVINDPNNQTVLHSIMIYNRMIKKMIIYDNDHSELIPSQSVYGLLDSVELALKKLREAFFQEKMLLTDKELASLIIQNKVLTKHETNDNLIGILNEATLYNCLGCLSYLYKNLAGYGESLPNILSFTGISKYEHEERETLRRALLIVKEKQTNKDN
>NZ_CP048621.1|WP_163762085.1|2961694_2962114_-|hypothetical-protein
MNKKALYFIGAVIALSGCGYKNEYSGVDKSHCDTIYNEFKTSFDSADVCIDENLSKLYNTGTNQELLEVIYYKCRKDLNTSNKAYLNSIYCKMAQDNNESYFTINESISEKTEYEYLNRIEQDTKHEILEKIMKYRSEK
>NZ_CP048621.1|WP_163762084.1|2961221_2961488_-|hypothetical-protein
MTQSPAVAEKTAALIASCLLKYRLKSAVVDYSEGSMFTLFRLAPSPRIRSSQISALIPELCRSLNVTEIRMIDFIPGTGQVFNGLIMG
>NZ_CP048621.1|WP_014658063.1|2974877_2975813_-|flagellar-hook-filament-junction-protein-FlgL
MRLSTNMIYHQRLQDMNNAQARWMDAGSQLASGKRVSKPSDDPQASSQAVRVNQSENRNQQYVASRGFAKTGMLLQMSVLTQMTEVTTQIDTTIIQASNQGSLSDSDRMSLAEQLSGLKDQLVALGNTTDGNGRYIFAGYKSDKPPFEVNAAGDVIYKGGDKAIMQNVSSDREMTTYFTGAQVFATDSNNVVNVFKALNEGIAALKTPQDQATQSEKEAAQKALDSANTAVKSALDKISNIESKQGLQLQEIDQLNFLADTRSIQNSQRISELLDTNWTGVTTDYYKEMAMFQASQDIFKDLNSMSLFGGR
>NZ_CP048621.1|WP_014658062.1|2975840_2977481_-|flagellar-hook-associated-protein-FlgK
MLNNVMNNALSGVNAAQGGLSVISNNLANAGVGYYHRQSAVFGENPGTMTPNGYFGNGTYFSHVRREFDEFINQQYGQSRARSGEYEAYAKNSSQVDDLLTNDIEDISSNIGSFFTALDAASSDASDKTLIDVFLGKSNALVGQFKEADRRLQEMERDVNRQIETKVKDINTYAEKIAGLNQQIARVRSVSGSEPNDLLDVRDRLVSEINSLIGVKVIEQNGNYNVTFANGLPLVTGENANRLEAVPSSQDDSRFSIGFVGANGQVREIADDAFRGGELSGVLRSRKEVIDPAYQKLNKLALVFASKFNEVHKKGFDANGNPGKDFFEIGKGNVVSNTFNRGKAEFDFNYSDVSQVTGNNYEMRFDGKEWNVTRLPEGFAVTVDRSTPDTLKFDGIELKITQNNAQSGDSFLVKPVNGVINGMQSLISDAANFAAAGEKGSGPGDNDNLKELVKLQDQKLIGGTSTFSDYYATIVNDVGNQTKQAQIDSETQNKMTESFYQQEQAVSGVNMNEESIQMQKIQQFFNANAQVLKTVDDLFNALMRAF
>NZ_CP048621.1|WP_004918619.1|2977725_2978706_-|flagellar-assembly-peptidoglycan-hydrolase-FlgJ
MNDMQLMQGAAFDLQSLSHLKRELTDSPDKGLRQVTQQLEATFVQMMLKSMRDALPQDGLFSSDQTRMLTSMYDQQIAQDLSQKGLGFGEMMYQQLTQMQGDTSSEDVPVKPFNMDDRLIDSLPNQAMAQIVRRFAPLGDALSSSMQKVKSLSLNSQNFISRLIEPAKVASQKSGISHLLVLAQAALESGWGRREILTAEGKTSHNLFGIKAGKSWQGPVTNIMTTEVINGKSIKMRDDFRVYGSYEEAIADYINLLTENPRYRDVKHAQSPEVAARRLHQAGYATDPNYADKLITLINQIRGYQTADKAASRAVQAYTVDLSDIF
>NZ_CP048621.1|WP_014658061.1|2978705_2979809_-|flagellar-basal-body-P-ring-protein-FlgI
MNKLVTLLLTLLCLFATSAYSERIKDLTTVQGVRDNALIGYGLVVGLDGTGDQTMQTPFTTQSLSNMLSQMGITVPPGTNMQLKNVAAVMVTAKLPPFARSGQAVDVVVSSMGNAKSLRGGTLLMTPLKGVDGQVYAMAQGNILVGGAGASAGGSSIKVNQLAGGRITGGATIERELPTSFGQNGIINLQLNDDSFTLAQDISDAINRLRGAGTATPLDSRTVQLRVPMNNSDQVRFLAQIQELNVRTPIAEAKVILNSRTGSVVINRSVTLESCAVAHGSLSVMVERQTQVSQPNTPFAGGQTVVTRNTNIGVREQGGALQKVNASVQLNQVIQALNTLGATPTDLMSILQAMESAGCLRAKLEII
>NZ_CP048621.1|WP_014658060.1|2979850_2980582_-|flagellar-basal-body-L-ring-protein-FlgH
MTKNGFTPEIKGDSFFSPSKVLVIALVLATSGCAYVKPRPLVDTQTSALPTAPTAPAPNGAIFQSAQPAYYGYQPLFEDRRPRNVGDILTINLQENVSASKNSSANANRSGKTGFLAAILPGFMQGWLGGSNTELDVKGSSDFSGKGGANANNTFRGTITVTVDQLLANGNLHVVGEKRIAINQGTESIRFSGVVNPRTIGADNNVSSTQVADARIEYVGDGYINESQTMGWLQRFFLNVSPY
>NZ_CP048621.1|WP_104873393.1|2980707_2981490_-|flagellar-basal-body-rod-protein-FlgG
MIRSLWIAKTGLDTQQTNLDVISNNLANVSTNGFKRQRAVFEDLLYQNIRQPGAMSSEQTSLPSGLQLGTGSRPVATMRIHSQGALNKTGNTTDIAIKGQGFLHVQLPDGTDAYTRDGALQPNQDGQLVTSSGYQIVPAITIPDNANSLTIARDGTVSITVYGDNQPQQIGQITLTTFINDAGLESMGENLYMETASSGASNESAPGTNGAGLLYQHMLETSNVNVAEELVNMIQTQRAYEINSKAVSASDQMLQRLTQL
>NZ_CP048621.1|WP_004918610.1|2981509_2982265_-|flagellar-hook-basal-body-complex-protein
MDHVIYTAMGGARHALENQAIVSNNIANVSTSGFKAQLAAMRAVPIHGDSEQTRTLVVASTPGADMSQGPLNYTGRPMDVALNDKHFLAVELADGSEAYTRNGNIQISPDGELVIGERRLQGDGGPINVPPNAELTIGEDGTVTALLATDPPTMLGQIGRLKVVEAQPQDLIRGEDGLFHLSPQAAAANGNGLAQSERASVTSGVIEGSNVNAAEAMVSMIANARYFEMQMKVVRSADENAQKANQLLAVS
>NZ_CP048621.1|WP_004918608.1|2982280_2983501_-|flagellar-hook-protein-FlgE
MSFSQAVSGLNAASAGLDSIGNNIANSATNGFKGATTSFADMFAGSGVGLGVNVAAVTQNFKDGPITRTDRPTDVAISGNGFFRVQDQNGDIFYSRDGQFIRDKSGNLVNNQGMTVTGYPAGLDENGNVVVQSGGVPQGLNIPTDMMDAQASDLAKLTINLNSEDKVKSKPFDINNPDDTGSYNFSTTMTAFDSQGNTHEISVYFVKTDDNKWTAYAKDAGDKVAKKLGDMEFDGNGRLNSPTNAVFAFDYQGLNGANNGTLQIDLNKTRQQKVSESSVSAIDVNGYPAGEYTNFKVEDNGLIVANYSNQQKRVVGQVALSAFANPNGLVSQGGNVWAPSNASGNPMDGVPGVGQFGKLTSGALESSNVDMSQELINMIVMQRNYQSNAQTIKTQDQMLQTMVNLR
>NZ_CP048621.1|WP_061064158.1|2983531_2984371_-|flagellar-basal-body-rod-modification-protein
MGIAATMYDSLDNTTAGPEPLKSNIPNKNKSQTDDMRDTFLKMIVTQMQNQDPTKPMENAELTSQLAQIATLESMNKLSDKVSGISSQIGSGQSLQATQLVGKGVLIPRNEIVLAPLKTQNDSDNTAISKPTNPLPDDETSRALSAANDNGGDDDASQGDYISSPFGFFLPKMADSVEITIRDKNRAIIRTISYDTEVKPDIYDMSWDGRDDNGKLVADTNSKYFFDVRAVSNGAEIEVTKLGYTRVNGVTPGTDAPLLDVGIGQSVPLSSIFKVYPSS
>NZ_CP048621.1|WP_004918605.1|2984383_2984788_-|flagellar-basal-body-rod-protein-FlgC
MALLSIFDISASALTAQSQRLNVSASNMANAESVVGPDGEPFRAKQVVFQMTPQGRNGVGGVRVSQLIEDPTPPRMEYKPGHPLADEKGYVRMPNVDMVGEMINTISASRSYQANLEVMNTAKTLLQKTLTIGQ

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP048621_6	6.6\|2922843\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2922843-2922874	32	MW145137	Providencia phage PSTNGR2lys, complete genome	36775-36806	0	1.0
NZ_CP048621_1	1.9\|1398022\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	1398022-1398053	32	MK047643	Phage NGI136, complete genome	311-342	2	0.938
NZ_CP048621_4	4.4\|2830833\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2830833-2830864	32	MK047638	Phage NG54, complete genome	28128-28159	4	0.875
NZ_CP048621_3	3.1\|2823306\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2823306-2823337	32	MK448589	Streptococcus satellite phage Javan632, complete genome	6216-6247	5	0.844
NZ_CP048621_2	2.1\|1788292\|52\|NZ_CP048621\|PILER-CR	1788292-1788343	52	LR134125	Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 5	411901-411952	6	0.885
NZ_CP048621_2	2.2\|1788398\|51\|NZ_CP048621\|PILER-CR	1788398-1788448	51	LR134125	Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 5	411902-411952	6	0.882
NZ_CP048621_3	3.1\|2823306\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2823306-2823337	32	MK672805	Vibrio phage Va_PF430-3_p42, complete genome	19868-19899	6	0.812
NZ_CP048621_3	3.1\|2823306\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2823306-2823337	32	NC_008761	Polaromonas naphthalenivorans CJ2 plasmid pPNAP05, complete sequence	25159-25190	6	0.812
NZ_CP048621_3	3.1\|2823306\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2823306-2823337	32	NC_008757	Polaromonas naphthalenivorans CJ2 plasmid pPNAP01, complete sequence	193871-193902	6	0.812
NZ_CP048621_3	3.1\|2823306\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2823306-2823337	32	NC_008757	Polaromonas naphthalenivorans CJ2 plasmid pPNAP01, complete sequence	316066-316097	6	0.812
NZ_CP048621_3	3.1\|2823306\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2823306-2823337	32	MN856005	Myoviridae sp. isolate 302, complete genome	3071-3102	6	0.812
NZ_CP048621_7	7.1\|2974320\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2974320-2974351	32	HQ906666	Wolbachia endosymbiont wVitB of Nasonia vitripennis phage WOVitB segment 2, partial genome	23266-23297	6	0.812
NZ_CP048621_7	7.1\|2974320\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2974320-2974351	32	KX522565	Wolbachia phage WO, complete genome	28802-28833	6	0.812
NZ_CP048621_7	7.1\|2974320\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2974320-2974351	32	HQ906662	Wolbachia endosymbiont wVitA of Nasonia vitripennis phage WOVitA1, complete sequence	53894-53925	6	0.812
NZ_CP048621_3	3.3\|2823426\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2823426-2823457	32	NZ_CP022523	Pseudoalteromonas sp. NC201 plasmid pNC201, complete sequence	784728-784759	7	0.781
NZ_CP048621_6	6.1\|2922542\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2922542-2922573	32	NZ_CP026273	Klebsiella oxytoca strain KONIH4 plasmid pKOX-ea2b, complete sequence	139298-139329	7	0.781
NZ_CP048621_6	6.3\|2922662\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2922662-2922693	32	MN693436	Marine virus AFVG_25M57, complete genome	14332-14363	7	0.781
NZ_CP048621_6	6.3\|2922662\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2922662-2922693	32	MN693320	Marine virus AFVG_25M58, complete genome	14329-14360	7	0.781
NZ_CP048621_6	6.1\|2922542\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2922542-2922573	32	NC_019893	Singulisphaera acidiphila DSM 18658 plasmid pSINAC01, complete sequence	46472-46503	8	0.75
NZ_CP048621_6	6.6\|2922843\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2922843-2922874	32	NZ_CP044357	Acinetobacter baumannii strain CAM180-1 plasmid pCAM180A, complete sequence	67184-67215	8	0.75
NZ_CP048621_6	6.6\|2922843\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2922843-2922874	32	NZ_CP041149	Acinetobacter baumannii strain CUVET-MIC596 plasmid pCUVET596, complete sequence	60108-60139	8	0.75
NZ_CP048621_6	6.6\|2922843\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2922843-2922874	32	NZ_CP040913	Acinetobacter pittii strain AB17H194 plasmid pAB17H194-2, complete sequence	17491-17522	8	0.75
NZ_CP048621_6	6.6\|2922843\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2922843-2922874	32	NZ_CP014652	Acinetobacter sp. DUT-2 plasmid unnamed1, complete sequence	6131-6162	8	0.75
NZ_CP048621_6	6.6\|2922843\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2922843-2922874	32	NZ_CP014654	Acinetobacter sp. DUT-2 plasmid unnamed3, complete sequence	7187-7218	8	0.75
NZ_CP048621_7	7.1\|2974320\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2974320-2974351	32	NC_019739	Microcoleus sp. PCC 7113 plasmid pMIC7113.01, complete sequence	63427-63458	8	0.75
NZ_CP048621_7	7.4\|2974501\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2974501-2974532	32	NC_015250	Acinetobacter phage 133, complete genome	120243-120274	8	0.75
NZ_CP048621_1	1.5\|1397782\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	1397782-1397813	32	NZ_CP027393	Escherichia coli O104:H4 strain FDAARGOS_349 plasmid unnamed4	10188-10219	9	0.719
NZ_CP048621_5	5.2\|2849455\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2849455-2849486	32	MT670420	Pseudomonas phage phiPsa347, complete genome	74089-74120	9	0.719
NZ_CP048621_5	5.2\|2849455\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2849455-2849486	32	MT670417	Pseudomonas phage phiPsa267, complete genome	74104-74135	9	0.719
NZ_CP048621_5	5.4\|2849575\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2849575-2849606	32	NZ_CP015595	Acinetobacter sp. NCu2D-2 plasmid unnamed, complete sequence	73645-73676	9	0.719
NZ_CP048621_5	5.7\|2849755\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2849755-2849786	32	NZ_CP045351	Vibrio sp. THAF100 plasmid pTHAF100_a, complete sequence	1154525-1154556	9	0.719
NZ_CP048621_7	7.1\|2974320\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2974320-2974351	32	MN693644	Marine virus AFVG_250M1161, complete genome	30248-30279	9	0.719
NZ_CP048621_7	7.1\|2974320\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2974320-2974351	32	NZ_CP035561	Lactobacillus plantarum strain SRCM103297 plasmid unnamed5	23517-23548	9	0.719
NZ_CP048621_7	7.1\|2974320\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2974320-2974351	32	JQ692107	Vibrio vulnificus phage SSP002, complete genome	46826-46857	9	0.719
NZ_CP048621_7	7.1\|2974320\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2974320-2974351	32	MN215888	Vibrio phage vB_VpaS_HCMJ, complete genome	46939-46970	9	0.719
NZ_CP048621_7	7.1\|2974320\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2974320-2974351	32	MF754116	Vibrio phage vB_VpaS_KF6, complete genome	45028-45059	9	0.719
NZ_CP048621_7	7.1\|2974320\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2974320-2974351	32	MF754115	Vibrio phage vB_VpaS_KF5, complete genome	46945-46976	9	0.719
NZ_CP048621_7	7.1\|2974320\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2974320-2974351	32	MN694432	Marine virus AFVG_250M20, complete genome	25511-25542	9	0.719
NZ_CP048621_7	7.1\|2974320\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2974320-2974351	32	MG602476	Vibrio phage VVP001, complete genome	28095-28126	9	0.719
NZ_CP048621_7	7.1\|2974320\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2974320-2974351	32	MN693757	Marine virus AFVG_250M21, complete genome	25568-25599	9	0.719
NZ_CP048621_7	7.1\|2974320\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2974320-2974351	32	MH925090	UNVERIFIED: Vibrio phage ValLY_3, complete genome	24370-24401	9	0.719
NZ_CP048621_1	1.6\|1397842\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	1397842-1397873	32	MH622943	Myoviridae sp. isolate ctbc_4, complete genome	223220-223251	10	0.688
NZ_CP048621_2	2.2\|1788398\|51\|NZ_CP048621\|PILER-CR	1788398-1788448	51	LR134125	Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 5	411695-411745	10	0.804
NZ_CP048621_3	3.1\|2823306\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2823306-2823337	32	NZ_CP012104	Bacillus thuringiensis strain HS18-1 plasmid pHS18-5, complete sequence	33195-33226	10	0.688
NZ_CP048621_6	6.1\|2922542\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2922542-2922573	32	NZ_CP020331	Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM593, complete sequence	345137-345168	10	0.688
NZ_CP048621_6	6.1\|2922542\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2922542-2922573	32	NC_023600	Mycobacterium phage Jolie1, complete genome	56807-56838	10	0.688
NZ_CP048621_6	6.1\|2922542\|32\|NZ_CP048621\|PILER-CR,CRISPRCasFinder,CRT	2922542-2922573	32	NC_024145	Mycobacterium phage Hosp, complete genome	54889-54920	10	0.688
NZ_CP048621_2	2.1\|1788292\|52\|NZ_CP048621\|PILER-CR	1788292-1788343	52	LR134125	Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 5	411694-411745	11	0.788
NZ_CP048621_2	2.2\|1788398\|51\|NZ_CP048621\|PILER-CR	1788398-1788448	51	MT713136	Aeromonas phage AP1, complete genome	243468-243518	12	0.765

1. spacer 6.6|2922843|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to MW145137 (Providencia phage PSTNGR2lys, complete genome) position: , mismatch: 0, identity: 1.0

caaatgaaggcttgaaaaaataatctttgtca	CRISPR spacer
caaatgaaggcttgaaaaaataatctttgtca	Protospacer
********************************

2. spacer 1.9|1398022|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to MK047643 (Phage NGI136, complete genome) position: , mismatch: 2, identity: 0.938

aaatggtaaagcggttgcatcttttagtttac	CRISPR spacer
aaatggtaaggcggttgcatcttttagtttgc	Protospacer
*********.********************.*

3. spacer 4.4|2830833|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to MK047638 (Phage NG54, complete genome) position: , mismatch: 4, identity: 0.875

aaaacaacgattgcccctgcaaaaaatgcgcc	CRISPR spacer
agcacaacgattgccccagcaaaaaatgcacc	Protospacer
*. ************** ***********.**

4. spacer 3.1|2823306|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to MK448589 (Streptococcus satellite phage Javan632, complete genome) position: , mismatch: 5, identity: 0.844

gtcatcaagcaccagtaaatcaacctcacaca	CRISPR spacer
gtcatcaagcaccaggtaatcaacctctttca	Protospacer
***************  ********** . **

5. spacer 2.1|1788292|52|NZ_CP048621|PILER-CR matches to LR134125 (Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 5) position: , mismatch: 6, identity: 0.885

tggtcgcaggttcgaatcctgcacgacccaccatcttaatattaaaatcagt	CRISPR spacer
tggtcgcaggttcgaatcctgcacgacccaccatcttaatgatgaggtcggt	Protospacer
****************************************. *.*..**.**

6. spacer 2.2|1788398|51|NZ_CP048621|PILER-CR matches to LR134125 (Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 5) position: , mismatch: 6, identity: 0.882

tggtcgcaggttcgaatcctgcacgacccaccatcttaatattaaaatcag	CRISPR spacer
tggtcgcaggttcgaatcctgcacgacccaccatcttaatgatgaggtcgg	Protospacer
****************************************. *.*..**.*

7. spacer 3.1|2823306|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to MK672805 (Vibrio phage Va_PF430-3_p42, complete genome) position: , mismatch: 6, identity: 0.812

gtcatcaagcaccagtaaatcaacctcacaca	CRISPR spacer
ttcatcaagcaccagtagatcaacctggctaa	Protospacer
 ****************.******** .*  *

8. spacer 3.1|2823306|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to NC_008761 (Polaromonas naphthalenivorans CJ2 plasmid pPNAP05, complete sequence) position: , mismatch: 6, identity: 0.812

gtcatcaagcaccagtaaatcaacctcacaca	CRISPR spacer
gtcatcaatcaccagtaaatcaagcttggcca	Protospacer
******** ************** **..  **

9. spacer 3.1|2823306|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to NC_008757 (Polaromonas naphthalenivorans CJ2 plasmid pPNAP01, complete sequence) position: , mismatch: 6, identity: 0.812

gtcatcaagcaccagtaaatcaacctcacaca	CRISPR spacer
gtcatcaatcaccagtaaatcaagcttggcca	Protospacer
******** ************** **..  **

10. spacer 3.1|2823306|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to NC_008757 (Polaromonas naphthalenivorans CJ2 plasmid pPNAP01, complete sequence) position: , mismatch: 6, identity: 0.812

gtcatcaagcaccagtaaatcaacctcacaca	CRISPR spacer
gtcatcaatcaccagtaaatcaagcttggcca	Protospacer
******** ************** **..  **

11. spacer 3.1|2823306|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to MN856005 (Myoviridae sp. isolate 302, complete genome) position: , mismatch: 6, identity: 0.812

gtcatcaagcaccagtaaatcaacctcacaca	CRISPR spacer
atcatcaagcaccaggacatcaacctctttca	Protospacer
.************** * ********* . **

12. spacer 7.1|2974320|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to HQ906666 (Wolbachia endosymbiont wVitB of Nasonia vitripennis phage WOVitB segment 2, partial genome) position: , mismatch: 6, identity: 0.812

gtcataaacttctttagctttcgcttgctctg-	CRISPR spacer
gagataaagttctttagcttttgctt-ttctgc	Protospacer
*  ***** ************.**** .****

13. spacer 7.1|2974320|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to KX522565 (Wolbachia phage WO, complete genome) position: , mismatch: 6, identity: 0.812

gtcataaacttctttagctttcgcttgctctg-	CRISPR spacer
gagataaagttctttagcttttgctt-ttctgc	Protospacer
*  ***** ************.**** .****

14. spacer 7.1|2974320|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to HQ906662 (Wolbachia endosymbiont wVitA of Nasonia vitripennis phage WOVitA1, complete sequence) position: , mismatch: 6, identity: 0.812

gtcataaacttctttagctttcgcttgctctg-	CRISPR spacer
gagataaagttctttagcttttgctt-ttctgc	Protospacer
*  ***** ************.**** .****

15. spacer 3.3|2823426|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022523 (Pseudoalteromonas sp. NC201 plasmid pNC201, complete sequence) position: , mismatch: 7, identity: 0.781

taattgcggtgcgcaatcagctcaaatgattg	CRISPR spacer
aaattgcgatgcgcaatcagctcataaaatac	Protospacer
 *******.*************** * .**

16. spacer 6.1|2922542|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026273 (Klebsiella oxytoca strain KONIH4 plasmid pKOX-ea2b, complete sequence) position: , mismatch: 7, identity: 0.781

tcggtttcgccttgttcaacacgaacaacaac	CRISPR spacer
tcaggagtgccttgttcaacatcaacaacaac	Protospacer
**.*   .*************. *********

17. spacer 6.3|2922662|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to MN693436 (Marine virus AFVG_25M57, complete genome) position: , mismatch: 7, identity: 0.781

ttcttgatgacactccaatagcaaatgcggac	CRISPR spacer
ttcttgatgacactccaatactaaattcaaca	Protospacer
******************** .**** *..

18. spacer 6.3|2922662|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to MN693320 (Marine virus AFVG_25M58, complete genome) position: , mismatch: 7, identity: 0.781

ttcttgatgacactccaatagcaaatgcggac	CRISPR spacer
ttcttgatgacactccaatactaaattcaaca	Protospacer
******************** .**** *..

19. spacer 6.1|2922542|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to NC_019893 (Singulisphaera acidiphila DSM 18658 plasmid pSINAC01, complete sequence) position: , mismatch: 8, identity: 0.75

tcggtt-tcgccttgttcaacacgaacaacaac	CRISPR spacer
-cgatcgtcgtcttgttcaacgcgaacaacctt	Protospacer
 **.*. ***.**********.********  .

20. spacer 6.6|2922843|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP044357 (Acinetobacter baumannii strain CAM180-1 plasmid pCAM180A, complete sequence) position: , mismatch: 8, identity: 0.75

caaatgaaggcttgaaaaaataatctttgtca	CRISPR spacer
aagaactaagcttaaaaaaataatctttttca	Protospacer
 *.*   *.****.************** ***

21. spacer 6.6|2922843|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP041149 (Acinetobacter baumannii strain CUVET-MIC596 plasmid pCUVET596, complete sequence) position: , mismatch: 8, identity: 0.75

caaatgaaggcttgaaaaaataatctttgtca	CRISPR spacer
aagaactaagcttaaaaaaataatctttttca	Protospacer
 *.*   *.****.************** ***

22. spacer 6.6|2922843|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040913 (Acinetobacter pittii strain AB17H194 plasmid pAB17H194-2, complete sequence) position: , mismatch: 8, identity: 0.75

caaatgaaggcttgaaaaaataatctttgtca	CRISPR spacer
aagaactaagcttaaaaaaataatctttttca	Protospacer
 *.*   *.****.************** ***

23. spacer 6.6|2922843|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014652 (Acinetobacter sp. DUT-2 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

caaatgaaggcttgaaaaaataatctttgtca	CRISPR spacer
aagaactaagcttaaaaaaataatctttttca	Protospacer
 *.*   *.****.************** ***

24. spacer 6.6|2922843|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014654 (Acinetobacter sp. DUT-2 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.75

caaatgaaggcttgaaaaaataatctttgtca	CRISPR spacer
aagaactaagcttaaaaaaataatctttttca	Protospacer
 *.*   *.****.************** ***

25. spacer 7.1|2974320|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to NC_019739 (Microcoleus sp. PCC 7113 plasmid pMIC7113.01, complete sequence) position: , mismatch: 8, identity: 0.75

gtcataaacttctttagctttcgcttgctctg	CRISPR spacer
aacttaaactgttttagctttcgcttggggtg	Protospacer
. * ****** .***************   **

26. spacer 7.4|2974501|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to NC_015250 (Acinetobacter phage 133, complete genome) position: , mismatch: 8, identity: 0.75

aaaagatgacaatgataaatgcca---tgtttgca	CRISPR spacer
caaagatgacaatgatgaatggcaacctattc---	Protospacer
 ***************.**** **   *.**.

27. spacer 1.5|1397782|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP027393 (Escherichia coli O104:H4 strain FDAARGOS_349 plasmid unnamed4) position: , mismatch: 9, identity: 0.719

----aatatcccaatcaaccagcggaaacacttgta	CRISPR spacer
cgacagtg----aatcaaccagcggaaacggttgtt	Protospacer
    *.*.    *****************. ****

28. spacer 5.2|2849455|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to MT670420 (Pseudomonas phage phiPsa347, complete genome) position: , mismatch: 9, identity: 0.719

cagttgaggcaggttgtgagccttgtttgtat	CRISPR spacer
acgcctgaacaggttgtgagccttgtctgtat	Protospacer
  *.. ...*****************.*****

29. spacer 5.2|2849455|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to MT670417 (Pseudomonas phage phiPsa267, complete genome) position: , mismatch: 9, identity: 0.719

cagttgaggcaggttgtgagccttgtttgtat	CRISPR spacer
acgcctgaacaggttgtgagccttgtctgtat	Protospacer
  *.. ...*****************.*****

30. spacer 5.4|2849575|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015595 (Acinetobacter sp. NCu2D-2 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

tgacataaatactactaattcctgagctaagt	CRISPR spacer
tgcaggaaatcctgctaattcctgagctacag	Protospacer
**  . **** **.*************** .

31. spacer 5.7|2849755|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045351 (Vibrio sp. THAF100 plasmid pTHAF100_a, complete sequence) position: , mismatch: 9, identity: 0.719

atgagcaaatggctattgatgccttgtttaat	CRISPR spacer
ttgcattggtggctatttatgccttgtttgat	Protospacer
 ** .. ..******** ***********.**

32. spacer 7.1|2974320|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to MN693644 (Marine virus AFVG_250M1161, complete genome) position: , mismatch: 9, identity: 0.719

gtcataaacttctttagctttcgcttgctctg	CRISPR spacer
atcataaaattctttagctttagctgctaacg	Protospacer
.******* ************ ***  .  .*

33. spacer 7.1|2974320|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP035561 (Lactobacillus plantarum strain SRCM103297 plasmid unnamed5) position: , mismatch: 9, identity: 0.719

gtcataaacttctttagctttcgcttgctctg	CRISPR spacer
ggattaaacttcttaagctttcgcctgtttgt	Protospacer
*   ********** *********.**.*.

34. spacer 7.1|2974320|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to JQ692107 (Vibrio vulnificus phage SSP002, complete genome) position: , mismatch: 9, identity: 0.719

gtcataaacttctttagctttcgcttgctctg	CRISPR spacer
tgctttttcttctttagctggcgcttgctctt	Protospacer
  * *   ***********  **********

35. spacer 7.1|2974320|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to MN215888 (Vibrio phage vB_VpaS_HCMJ, complete genome) position: , mismatch: 9, identity: 0.719

gtcataaacttctttagctttcgcttgctctg	CRISPR spacer
tgctttttcttctttagctggcgcttgctctt	Protospacer
  * *   ***********  **********

36. spacer 7.1|2974320|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to MF754116 (Vibrio phage vB_VpaS_KF6, complete genome) position: , mismatch: 9, identity: 0.719

gtcataaacttctttagctttcgcttgctctg	CRISPR spacer
tgctttttcttctttagctggcgcttgctctt	Protospacer
  * *   ***********  **********

37. spacer 7.1|2974320|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to MF754115 (Vibrio phage vB_VpaS_KF5, complete genome) position: , mismatch: 9, identity: 0.719

gtcataaacttctttagctttcgcttgctctg	CRISPR spacer
tgctttttcttctttagctggcgcttgctctt	Protospacer
  * *   ***********  **********

38. spacer 7.1|2974320|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to MN694432 (Marine virus AFVG_250M20, complete genome) position: , mismatch: 9, identity: 0.719

gtcataaacttctttagctttcgcttgctctg	CRISPR spacer
ttcataaacttttttagctttagcaagtcttt	Protospacer
 **********.********* **  *...*

39. spacer 7.1|2974320|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to MG602476 (Vibrio phage VVP001, complete genome) position: , mismatch: 9, identity: 0.719

gtcataaacttctttagctttcgcttgctctg	CRISPR spacer
tgctttttcttctttagctggcgcttgctctt	Protospacer
  * *   ***********  **********

40. spacer 7.1|2974320|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to MN693757 (Marine virus AFVG_250M21, complete genome) position: , mismatch: 9, identity: 0.719

gtcataaacttctttagctttcgcttgctctg	CRISPR spacer
ttcataaacttttttagctttagcaagtcttt	Protospacer
 **********.********* **  *...*

41. spacer 7.1|2974320|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to MH925090 (UNVERIFIED: Vibrio phage ValLY_3, complete genome) position: , mismatch: 9, identity: 0.719

gtcataaacttctttagctttcgcttgctctg	CRISPR spacer
tgctttttcttctttagctggcgcttgctctt	Protospacer
  * *   ***********  **********

42. spacer 1.6|1397842|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to MH622943 (Myoviridae sp. isolate ctbc_4, complete genome) position: , mismatch: 10, identity: 0.688

tttatatgcatgtattaaagacaatcatgaag	CRISPR spacer
gattgatgcttatattaaagacaatcatattt	Protospacer
  *  **** *.****************.

43. spacer 2.2|1788398|51|NZ_CP048621|PILER-CR matches to LR134125 (Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 5) position: , mismatch: 10, identity: 0.804

tggtcgcaggttcgaatcctgcacgacccaccatcttaatattaaaatcag-------	CRISPR spacer
tggtcgcaggttcgaatcctgcacgacccaccatc-------taaaacgatggtgccg	Protospacer
***********************************       *****. *

44. spacer 3.1|2823306|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012104 (Bacillus thuringiensis strain HS18-1 plasmid pHS18-5, complete sequence) position: , mismatch: 10, identity: 0.688

gtcatcaagcaccagtaaatcaacctcacaca	CRISPR spacer
atcatcaagtaccaggaaatcaacgcttgtta	Protospacer
.********.***** ******** ..   .*

45. spacer 6.1|2922542|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020331 (Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM593, complete sequence) position: , mismatch: 10, identity: 0.688

tcggtttcgccttgttcaacacgaacaacaac	CRISPR spacer
cgtatttcgccttgttcatcacgaccatgatg	Protospacer
.  .************** ***** **  *

46. spacer 6.1|2922542|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to NC_023600 (Mycobacterium phage Jolie1, complete genome) position: , mismatch: 10, identity: 0.688

tcggtttcgccttgttcaacacgaacaacaac	CRISPR spacer
ccgggttcgccttgttcagcacgacggggctc	Protospacer
.*** *************.*****  ..   *

47. spacer 6.1|2922542|32|NZ_CP048621|PILER-CR,CRISPRCasFinder,CRT matches to NC_024145 (Mycobacterium phage Hosp, complete genome) position: , mismatch: 10, identity: 0.688

tcggtttcgccttgttcaacacgaacaacaac	CRISPR spacer
ccgggttcgccttgttcagcacgacggggctc	Protospacer
.*** *************.*****  ..   *

48. spacer 2.1|1788292|52|NZ_CP048621|PILER-CR matches to LR134125 (Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 5) position: , mismatch: 11, identity: 0.788

tggtcgcaggttcgaatcctgcacgacccaccatcttaatattaaaatcagt--------	CRISPR spacer
tggtcgcaggttcgaatcctgcacgacccaccatct--------aaaacgatggtgccga	Protospacer
************************************        *** *..*

49. spacer 2.2|1788398|51|NZ_CP048621|PILER-CR matches to MT713136 (Aeromonas phage AP1, complete genome) position: , mismatch: 12, identity: 0.765

tggtcgcaggttcgaatcctgcacgacccaccatc--------ttaatattaaaatcag	CRISPR spacer
tggtcgctggttcgaatccagcacgacccaccatctggcgggttcaatatc--------	Protospacer
******* *********** ***************        *.*****.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

98258 : 153190

Vibrio_phage(15.38%)

tRNA,transposase,integrase

attL 122256:122273|attR 160474:160491

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004916068.1\|98258_99302_-\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_104873096.1\|99321_100014_-	phosphoglycolate phosphatase	NA	NA	NA	NA
WP_004916064.1\|100010_100685_-	ribulose-phosphate 3-epimerase	NA	NA	NA	NA
WP_004916061.1\|100719_101604_-	adenine-specific DNA-methyltransferase	A0A1S6L1V5	Vibrio_phage	6.5e-70	50.9
WP_014657126.1\|101684_102590_-	SPOR domain-containing protein	NA	NA	NA	NA
WP_004916059.1\|102909_104004_-	3-dehydroquinate synthase	NA	NA	NA	NA
WP_004916057.1\|104038_104560_-	shikimate kinase AroK	NA	NA	NA	NA
WP_014657124.1\|105063_106101_-	transporter	A7BJX1	Enterobacteria_phage	8.9e-18	23.3
WP_004916055.1\|106090_106639_-	hypothetical protein	NA	NA	NA	NA
WP_040132636.1\|106631_107171_-	hypothetical protein	NA	NA	NA	NA
WP_040132637.1\|107157_108000_-	pilus assembly protein PilM	NA	NA	NA	NA
WP_014657121.1\|108116_110648_+	peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA	NA	NA	NA	NA
WP_004916049.1\|110776_111328_-	ADP compounds hydrolase NudE	NA	NA	NA	NA
WP_163761879.1\|111749_113843_+	intracellular growth attenuator family protein	NA	NA	NA	NA
WP_004916047.1\|113894_114302_+	ribosome-associated heat shock protein Hsp15	NA	NA	NA	NA
WP_004916045.1\|114387_115260_+	Hsp33 family molecular chaperone HslO	NA	NA	NA	NA
WP_004916041.1\|115464_117084_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	7.6e-141	52.5
WP_004916039.1\|117171_117870_-	pirin family protein	NA	NA	NA	NA
WP_040132638.1\|118408_119611_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_004916035.1\|120088_121576_+	inorganic phosphate transporter PitA	NA	NA	NA	NA
WP_004916033.1\|121696_122032_-	universal stress protein UspB	NA	NA	NA	NA
122256:122273	attL	NA	NA	NA	NA
WP_004916030.1\|122505_122940_+	universal stress protein UspA	NA	NA	NA	NA
WP_004916027.1\|123205_124537_+	NADP-specific glutamate dehydrogenase	NA	NA	NA	NA
WP_004916009.1\|124596_125361_-	16S rRNA (guanine(1516)-N(2))-methyltransferase RsmJ	NA	NA	NA	NA
WP_072502632.1\|125353_127396_-	oligopeptidase A	A0A1V0SD92	Indivirus	3.9e-41	21.5
WP_104873094.1\|127956_129174_+\|integrase	tyrosine-type recombinase/integrase	Q7M297	Enterobacteria_phage	3.2e-160	68.4
WP_163761880.1\|129910_130495_+	antirestriction protein ArdA	A0A0A8WIV6	Clostridium_phage	1.5e-25	41.5
WP_104873619.1\|131440_132916_+	SulP family inorganic anion transporter	A0A2H4J153	uncultured_Caudovirales_phage	5.2e-197	74.2
WP_163761881.1\|132918_133776_+	universal stress protein	A0A2H4J154	uncultured_Caudovirales_phage	1.4e-45	38.5
WP_104873091.1\|133847_135845_-	BCCT family transporter	A0A2I7QNT1	Vibrio_phage	1.1e-21	25.7
WP_158660886.1\|136014_136632_-	recombinase family protein	NA	NA	NA	NA
WP_163761882.1\|136820_139847_+\|transposase	Tn3 family transposase	NA	NA	NA	NA
WP_121875320.1\|139996_140701_+\|transposase	IS6 family transposase	A0A077SL39	Escherichia_phage	1.3e-113	82.3
WP_163762229.1\|140732_141245_+	recombinase family protein	NA	NA	NA	NA
WP_163761883.1\|141344_141485_+	hypothetical protein	NA	NA	NA	NA
WP_163761884.1\|141624_142863_-	hypothetical protein	NA	NA	NA	NA
WP_163761885.1\|142862_145268_-	CFA, I fimbrial subunit C usher protein	NA	NA	NA	NA
WP_163761886.1\|145344_145866_-	adhesin	NA	NA	NA	NA
WP_163761887.1\|145954_146701_-	hypothetical protein	NA	NA	NA	NA
WP_163762230.1\|146824_147127_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_163761888.1\|148108_148339_+\|transposase	transposase	Q716C1	Shigella_phage	5.3e-16	60.0
WP_163762231.1\|148405_149038_+\|transposase	IS3 family transposase	Q716C2	Shigella_phage	1.3e-67	67.2
WP_163761889.1\|149201_149837_-	recombinase family protein	NA	NA	NA	NA
WP_123382784.1\|150031_150298_+	DUF1778 domain-containing protein	NA	NA	NA	NA
WP_163761890.1\|150297_150777_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_163761891.1\|150894_152379_+	DUF2075 domain-containing protein	NA	NA	NA	NA
WP_121875320.1\|152485_153190_+\|transposase	IS6 family transposase	A0A077SL39	Escherichia_phage	1.3e-113	82.3
160474:160491	attR	NA	NA	NA	NA

DBSCAN-SWA_2

1034241 : 1174899

116

Escherichia_phage(22.86%)

tRNA,transposase,integrase

attL 1134323:1134337|attR 1178271:1178285

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014656657.1\|1034241_1036872_+\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	3.0e-78	37.0
WP_004264815.1\|1037099_1037285_+	carbon storage regulator CsrA	A0A2I7RT00	Vibrio_phage	4.9e-12	61.4
WP_040132889.1\|1038566_1040126_+	glutamate--cysteine ligase	NA	NA	NA	NA
WP_014656655.1\|1040284_1040800_+	S-ribosylhomocysteine lyase	NA	NA	NA	NA
WP_014656654.1\|1040864_1042151_-	DUF21 domain-containing protein	NA	NA	NA	NA
WP_004924889.1\|1042195_1042993_-	inner membrane protein YpjD	NA	NA	NA	NA
WP_004924888.1\|1043395_1044757_+	signal recognition particle protein	NA	NA	NA	NA
WP_004924887.1\|1044893_1045142_+	30S ribosomal protein S16	NA	NA	NA	NA
WP_004924886.1\|1045160_1045709_+	ribosome maturation factor RimM	NA	NA	NA	NA
WP_004924885.1\|1045747_1046512_+\|tRNA	tRNA (guanosine(37)-N1)-methyltransferase TrmD	NA	NA	NA	NA
WP_004914006.1\|1046559_1046913_+	50S ribosomal protein L19	NA	NA	NA	NA
WP_014656653.1\|1047347_1048436_+	3-deoxy-7-phosphoheptulonate synthase	A0A0F6R6T6	Escherichia_coli_O157_typing_phage	7.7e-89	51.5
WP_004924884.1\|1048450_1049572_+	bifunctional chorismate mutase/prephenate dehydrogenase	NA	NA	NA	NA
WP_004924883.1\|1049874_1051437_+	HAMP domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	9.0e-14	32.8
WP_036941497.1\|1051515_1052688_-	bifunctional chorismate mutase/prephenate dehydratase	NA	NA	NA	NA
WP_004924882.1\|1052794_1052983_+	hypothetical protein	NA	NA	NA	NA
WP_014656650.1\|1052977_1053307_-	ribosome-associated translation inhibitor RaiA	NA	NA	NA	NA
WP_004924881.1\|1053702_1054434_-	outer membrane protein assembly factor BamD	NA	NA	NA	NA
WP_004924880.1\|1054572_1055550_+	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	NA	NA	NA	NA
WP_088499061.1\|1055549_1056284_+	polyphenol oxidase	NA	NA	NA	NA
WP_004924878.1\|1056410_1058984_+	ATP-dependent chaperone ClpB	H6X3M6	Enterobacteria_phage	1.4e-128	35.0
WP_163761932.1\|1065278_1066124_+	endonuclease/exonuclease/phosphatase family protein	NA	NA	NA	NA
WP_004916265.1\|1066503_1067691_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_014656645.1\|1067704_1068097_+	hypothetical protein	NA	NA	NA	NA
WP_004922949.1\|1068114_1069308_+	methionine gamma-lyase	NA	NA	NA	NA
WP_104872924.1\|1069366_1070737_-	amino acid permease	NA	NA	NA	NA
WP_014656642.1\|1070893_1071565_+	7-carboxy-7-deazaguanine synthase QueE	A0A2I7S8X1	Vibrio_phage	1.1e-13	35.8
WP_004922942.1\|1071599_1071962_-	6-carboxytetrahydropterin synthase QueD	NA	NA	NA	NA
WP_104872923.1\|1072199_1074005_+	NADPH-dependent assimilatory sulfite reductase flavoprotein subunit	NA	NA	NA	NA
WP_104872922.1\|1074004_1075735_+	assimilatory sulfite reductase (NADPH) hemoprotein subunit	NA	NA	NA	NA
WP_104872921.1\|1075731_1076466_+	phosphoadenylyl-sulfate reductase	NA	NA	NA	NA
WP_001353740.1\|1078208_1078448_+	DUF1819 family protein	NA	NA	NA	NA
WP_070342364.1\|1079998_1080844_+	lincosamide nucleotidyltransferase Lnu(F)	NA	NA	NA	NA
WP_000777554.1\|1080840_1081314_+	trimethoprim-resistant dihydrofolate reductase DfrA1	A0A140HLG8	Bacillus_phage	1.6e-19	34.4
WP_001206316.1\|1081330_1082122_+	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA1	NA	NA	NA	NA
WP_000679427.1\|1082285_1082633_+	quaternary ammonium compound efflux SMR transporter QacE delta 1	NA	NA	NA	NA
WP_000259031.1\|1082626_1083466_+	sulfonamide-resistant dihydropteroate synthase Sul1	NA	NA	NA	NA
WP_000376616.1\|1083593_1083797_+	hypothetical protein	NA	NA	NA	NA
WP_000184001.1\|1083952_1085158_+	chromate efflux transporter	NA	NA	NA	NA
WP_001067855.1\|1085263_1085968_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_001199192.1\|1086081_1086858_+	aminoglycoside N-acetyltransferase AAC(3)-IV	NA	NA	NA	NA
WP_000171321.1\|1086878_1087100_+	hypothetical protein	NA	NA	NA	NA
WP_000742814.1\|1087086_1088112_+	aminoglycoside O-phosphotransferase APH(4)-Ia	NA	NA	NA	NA
WP_000602738.1\|1088533_1089286_-\|transposase	IS6 family transposase	A0A077SL39	Escherichia_phage	2.4e-41	44.7
WP_006581703.1\|1091096_1091582_+	hypothetical protein	NA	NA	NA	NA
WP_085940648.1\|1091778_1092869_-\|transposase	IS4 family transposase ISAba1	NA	NA	NA	NA
WP_001043260.1\|1092958_1093774_+	sulfonamide-resistant dihydropteroate synthase Sul2	NA	NA	NA	NA
WP_000251875.1\|1093860_1094163_+	phosphoglucosamine mutase	NA	NA	NA	NA
WP_001445143.1\|1094056_1094308_-	hypothetical protein	NA	NA	NA	NA
WP_001120888.1\|1094338_1095832_-\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_001255015.1\|1095943_1096249_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_000214122.1\|1096276_1097491_-	chloramphenicol/florfenicol efflux MFS transporter FloR	S4TR35	Salmonella_phage	1.2e-18	28.7
WP_001447541.1\|1097713_1098598_-	DUF3363 domain-containing protein	NA	NA	NA	NA
WP_001067784.1\|1099522_1100227_+\|transposase	IS6-like element IS1006 family transposase	A0A077SL39	Escherichia_phage	1.9e-120	85.8
WP_046788546.1\|1100311_1100713_-	hypothetical protein	NA	NA	NA	NA
WP_015344976.1\|1100721_1103673_-\|transposase	Tn3-like element TnAs3 family transposase	A0A1B0V7H9	Salmonella_phage	0.0e+00	73.5
WP_000147567.1\|1103675_1104236_-	recombinase family protein	A0A1B0V7I5	Salmonella_phage	4.0e-49	86.2
WP_000454193.1\|1104361_1104712_-	DUF3330 domain-containing protein	NA	NA	NA	NA
WP_000845039.1\|1104914_1105928_-\|integrase	class 1 integron integrase IntI1	A0A1P8DJJ6	Virus_Rctr41k	1.0e-71	45.5
WP_001083725.1\|1106072_1106570_+	trimethoprim-resistant dihydrofolate reductase DfrA12	A0A0A0PL85	Bacillus_phage	7.5e-23	40.9
WP_001336345.1\|1106681_1106972_+	DUF1010 domain-containing protein	NA	NA	NA	NA
WP_001206356.1\|1106977_1107769_+	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA2	NA	NA	NA	NA
WP_000679427.1\|1107932_1108280_+	quaternary ammonium compound efflux SMR transporter QacE delta 1	NA	NA	NA	NA
WP_000259031.1\|1108273_1109113_+	sulfonamide-resistant dihydropteroate synthase Sul1	NA	NA	NA	NA
WP_000050481.1\|1109517_1111059_+\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_004236386.1\|1111871_1113011_-	class C beta-lactamase DHA-1	NA	NA	NA	NA
WP_004193231.1\|1113121_1113997_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_025999322.1\|1114000_1114366_-	hydrogenase maturation nickel metallochaperone HypA	NA	NA	NA	NA
WP_052238321.1\|1114258_1114594_+	ethidium bromide resistance protein	NA	NA	NA	NA
WP_000259031.1\|1114587_1115427_+	sulfonamide-resistant dihydropteroate synthase Sul1	NA	NA	NA	NA
WP_000376623.1\|1115554_1116055_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_001163403.1\|1116589_1117372_-	ATP-binding protein	A0A2L1IVB6	Escherichia_phage	2.5e-33	35.0
WP_001324342.1\|1117361_1118885_-\|transposase	IS21-like element IS1326 family transposase	A0A2L1IVA1	Escherichia_phage	1.2e-15	24.2
WP_000344784.1\|1120602_1121463_-	AAA family ATPase	NA	NA	NA	NA
WP_001067855.1\|1121953_1122658_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_000018329.1\|1122808_1123624_+	aminoglycoside O-phosphotransferase APH(3')-Ia	A0A193DTG4	Autographa_californica_nuclear_polyhedrosis_virus	6.1e-163	100.0
WP_001067855.1\|1123813_1124518_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_140173007.1\|1124553_1124865_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_000155092.1\|1125054_1125939_-	Mph(E) family macrolide 2'-phosphotransferase	NA	NA	NA	NA
WP_000052512.1\|1125994_1127470_-	ABC-F type ribosomal protection protein Msr(E)	A0A1B0RXA0	Streptococcus_phage	2.3e-160	59.0
WP_001067855.1\|1127919_1128624_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_071538080.1\|1128648_1130223_+	PAS domain-containing protein	A0A1B0V854	Salmonella_phage	2.8e-87	99.4
WP_001276994.1\|1131025_1132693_-	AAA family ATPase	NA	NA	NA	NA
WP_000267723.1\|1132689_1134798_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
1134323:1134337	attL	NA	NA	NA	NA
WP_001029679.1\|1134784_1135606_-\|transposase	heteromeric transposase endonuclease subunit TnsA	NA	NA	NA	NA
WP_004922933.1\|1136019_1136667_-	beta-phosphoglucomutase	A0A1D8KNV9	Synechococcus_phage	6.4e-06	24.4
WP_061064736.1\|1136659_1139383_-	glycoside hydrolase family 65 protein	NA	NA	NA	NA
WP_004922928.1\|1139408_1140830_-	PTS trehalose transporter subunit IIBC	NA	NA	NA	NA
WP_004922927.1\|1140951_1141917_-	HTH-type transcriptional regulator TreR	NA	NA	NA	NA
WP_004922925.1\|1142228_1143641_+	uroporphyrinogen-III C-methyltransferase	NA	NA	NA	NA
WP_004922922.1\|1143656_1144565_+	sulfate adenylyltransferase subunit CysD	NA	NA	NA	NA
WP_040132390.1\|1144576_1146019_+	sulfate adenylyltransferase subunit CysN	A0A1V0SGC3	Hokovirus	4.0e-32	26.0
WP_014656632.1\|1146024_1146630_+	adenylyl-sulfate kinase	NA	NA	NA	NA
WP_004922916.1\|1147029_1147329_+	cell division protein FtsB	NA	NA	NA	NA
WP_014656631.1\|1147397_1148120_+	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	NA	NA	NA	NA
WP_004922911.1\|1148132_1148645_+	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	NA	NA	NA	NA
WP_014656630.1\|1148610_1149660_+\|tRNA	tRNA pseudouridine(13) synthase TruD	NA	NA	NA	NA
WP_004922907.1\|1149637_1150399_+	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	2.1e-69	54.1
WP_004922905.1\|1150395_1151022_+	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	1.7e-40	50.3
WP_014656629.1\|1151265_1152333_+	murein hydrolase activator NlpD	D7RWE0	Brochothrix_phage	1.6e-06	36.4
WP_004922901.1\|1152387_1153374_+	RNA polymerase sigma factor RpoS	M4SMP8	Cyanophage	6.7e-31	31.0
WP_004922898.1\|1153479_1154241_-\|tRNA	tRNA-(ms[2]io[6]A)-hydroxylase	NA	NA	NA	NA
WP_163761933.1\|1154242_1156807_-	DNA mismatch repair protein MutS	E3T5Q7	Cafeteria_roenbergensis_virus	2.5e-29	21.4
WP_159287705.1\|1157037_1158318_+\|integrase	tyrosine-type recombinase/integrase	A0A0R6PH06	Moraxella_phage	1.9e-09	23.2
WP_033929748.1\|1159302_1159578_-	hypothetical protein	NA	NA	NA	NA
WP_033929743.1\|1159881_1160094_+	helix-turn-helix transcriptional regulator	S5M643	Brevibacillus_phage	8.7e-05	42.3
WP_114502419.1\|1160132_1161245_-	hypothetical protein	A0A2H4J138	uncultured_Caudovirales_phage	2.9e-43	40.9
WP_114502418.1\|1161244_1161841_-	pancortin-3	NA	NA	NA	NA
WP_114502417.1\|1161866_1162601_-	M48 family metallopeptidase	NA	NA	NA	NA
WP_107111807.1\|1163760_1163832_+	hypothetical protein	NA	NA	NA	NA
WP_114502416.1\|1164070_1167352_-	type I restriction endonuclease subunit R	A0A220A398	Liberibacter_phage	1.8e-64	27.5
WP_163761934.1\|1167396_1169964_-	hypothetical protein	NA	NA	NA	NA
WP_114502414.1\|1169977_1171195_-	restriction endonuclease subunit S	NA	NA	NA	NA
WP_163761935.1\|1171184_1172708_-	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	1.1e-83	37.3
WP_163761936.1\|1172781_1173369_-	restriction endonuclease subunit S	NA	NA	NA	NA
WP_163761937.1\|1173510_1174899_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
1178271:1178285	attR	NA	NA	NA	NA

DBSCAN-SWA_3

1940231 : 1951322

Haemophilus_phage(44.44%)

tail,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_040133275.1\|1940231_1941743_+	DUF3383 domain-containing protein	Q7Y5T5	Haemophilus_phage	5.7e-98	40.6
WP_004921015.1\|1941752_1942187_+	DUF3277 family protein	NA	NA	NA	NA
WP_004921014.1\|1942186_1942579_+	hypothetical protein	NA	NA	NA	NA
WP_104873565.1\|1942723_1944508_+	hypothetical protein	NA	NA	NA	NA
WP_053110979.1\|1944590_1945322_+	hypothetical protein	Q7Y5T0	Haemophilus_phage	5.7e-27	34.0
WP_036940883.1\|1945318_1945657_+	hypothetical protein	NA	NA	NA	NA
WP_040133272.1\|1945631_1946456_+	hypothetical protein	Q7Y5S8	Haemophilus_phage	8.5e-72	48.4
WP_014656228.1\|1946452_1947109_+	hypothetical protein	Q7Y5S7	Haemophilus_phage	2.1e-33	50.7
WP_004920995.1\|1947108_1947471_+	hypothetical protein	A0A2H5BFY4	Vibrio_phage	2.5e-12	38.3
WP_004920993.1\|1947454_1948579_+\|plate	baseplate J/gp47 family protein	D0UIH5	Aggregatibacter_phage	2.2e-78	41.1
WP_104873564.1\|1948571_1949228_+	DUF2612 domain-containing protein	D0UIH4	Aggregatibacter_phage	1.3e-35	43.3
WP_104873563.1\|1949214_1950705_+	histidine kinase	M1TAS6	Escherichia_phage	6.1e-28	51.7
WP_104873562.1\|1950704_1951322_+\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	7.6e-33	42.3

DBSCAN-SWA_4

1992189 : 2035366

Acinetobacter_phage(36.17%)

tail,plate,terminase,lysis,head,integrase

attL 1983997:1984011|attR 2003280:2003294

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1983997:1984011	attL	NA	NA	NA	NA
WP_163761990.1\|1992189_1993365_-\|integrase	site-specific integrase	A0A2H4J1K3	uncultured_Caudovirales_phage	4.4e-29	30.7
WP_042851615.1\|1993366_1993579_-	hypothetical protein	NA	NA	NA	NA
WP_163761991.1\|1993553_1993757_-	hypothetical protein	H9C154	Pectobacterium_phage	2.0e-06	51.9
WP_163761992.1\|1994163_1994757_-	HNH endonuclease	M1PKJ5	Streptococcus_phage	5.2e-23	36.8
WP_163761993.1\|1994753_1994984_-	hypothetical protein	A0A2H4JCC5	uncultured_Caudovirales_phage	3.0e-11	62.1
WP_153673902.1\|1995231_1995732_-	hypothetical protein	H9C156	Pectobacterium_phage	4.5e-44	58.3
WP_163761994.1\|1995731_1997753_-	hypothetical protein	H9C157	Pectobacterium_phage	3.8e-121	38.0
WP_105881085.1\|1997765_1998017_-	hypothetical protein	NA	NA	NA	NA
WP_105881084.1\|1998025_1998358_-	hypothetical protein	NA	NA	NA	NA
WP_163761995.1\|1998850_1999492_-	LexA family transcriptional regulator	A0A1W6JP50	Morganella_phage	6.7e-32	37.3
WP_105881083.1\|1999599_1999785_+	hypothetical protein	A0A1W6JP24	Morganella_phage	7.3e-08	58.0
WP_004912077.1\|1999823_2000279_+	hypothetical protein	H9C162	Pectobacterium_phage	1.0e-26	51.4
WP_163761996.1\|2000296_2000521_+	hypothetical protein	H9C163	Pectobacterium_phage	7.3e-18	62.2
WP_163761997.1\|2000522_2001335_+	helix-turn-helix domain-containing protein	H9C164	Pectobacterium_phage	5.9e-41	78.3
WP_163761998.1\|2001327_2001918_+	ATP-binding protein	K7PLU3	Enterobacteria_phage	4.0e-47	48.9
WP_163762239.1\|2001917_2003285_+	replicative DNA helicase	A0A192Y673	Salmonella_phage	1.4e-100	45.5
WP_150375419.1\|2003478_2003715_+	hypothetical protein	NA	NA	NA	NA
2003280:2003294	attR	NA	NA	NA	NA
WP_163761999.1\|2004026_2004368_+	hypothetical protein	H9C172	Pectobacterium_phage	1.4e-33	64.2
WP_163762000.1\|2004418_2004934_-	hypothetical protein	NA	NA	NA	NA
WP_163762001.1\|2005158_2005752_+	DUF1367 family protein	H9C173	Pectobacterium_phage	1.2e-64	58.7
WP_163762002.1\|2005763_2006078_+	DUF968 domain-containing protein	A0A1I9KFA7	Aeromonas_phage	7.0e-35	69.8
WP_048607752.1\|2006065_2006596_+	DUF1133 family protein	I6S672	Salmonella_phage	9.7e-37	52.7
WP_163762003.1\|2006760_2006955_+	TrmB family transcriptional regulator	Q8SBE3	Shigella_phage	3.5e-08	62.7
WP_163762240.1\|2007110_2008148_+	site-specific DNA-methyltransferase	A0A1W6JP25	Morganella_phage	1.5e-142	75.2
WP_004912034.1\|2008186_2008456_+	phage protein	A0A2H4FNF0	Salmonella_phage	1.1e-25	67.8
WP_163762004.1\|2008455_2008914_+	lysozyme	A0A1W6JNW4	Morganella_phage	6.9e-47	58.7
WP_163762005.1\|2008895_2009078_+	hypothetical protein	NA	NA	NA	NA
WP_163762006.1\|2009064_2009496_+\|lysis	lysis protein	A0A2H4JHL8	uncultured_Caudovirales_phage	2.3e-12	41.3
WP_163762007.1\|2009597_2010476_+	hypothetical protein	NA	NA	NA	NA
WP_163762008.1\|2010574_2011585_+\|terminase	terminase small subunit	C5IHM0	Burkholderia_virus	2.9e-37	41.0
WP_163762009.1\|2011795_2012011_-	hypothetical protein	NA	NA	NA	NA
WP_163762010.1\|2012077_2013691_+	TerL protein	A9YWZ6	Burkholderia_phage	1.2e-202	66.3
WP_163762011.1\|2013691_2015221_+	DUF1073 domain-containing protein	E2GLW8	Acinetobacter_phage	1.8e-115	52.1
WP_163762241.1\|2015282_2015984_+\|head	phage head morphogenesis protein	A0A068CBK2	Acinetobacter_phage	8.0e-55	46.1
WP_163762012.1\|2015996_2017181_+	DUF2213 domain-containing protein	A0A1X9SFH3	Acinetobacter_phage	4.1e-67	54.3
WP_163762013.1\|2017190_2017676_+	hypothetical protein	A0A2R3UAX9	Myoviridae_environmental_samples	4.3e-15	39.0
WP_163762014.1\|2017685_2018681_+	DUF2184 domain-containing protein	I2GUD7	Acinetobacter_phage	6.4e-90	53.6
WP_163762015.1\|2018747_2019062_+	hypothetical protein	A0A1X9SFA9	Acinetobacter_phage	3.6e-07	33.6
WP_163762242.1\|2019086_2019551_+	DUF4054 domain-containing protein	A0A068CGG9	Acinetobacter_phage	3.6e-19	44.7
WP_163762016.1\|2019540_2020092_+	hypothetical protein	A0A190XCA2	Acinetobacter_phage	2.2e-15	29.4
WP_163762243.1\|2020087_2020465_+	hypothetical protein	E2GLU4	Acinetobacter_phage	3.6e-17	38.1
WP_163762017.1\|2020398_2020938_+	hypothetical protein	NA	NA	NA	NA
WP_163762018.1\|2020947_2022468_+	DUF3383 domain-containing protein	K4PB47	Acinetobacter_phage	7.8e-87	38.2
WP_163762019.1\|2022481_2022928_+	hypothetical protein	E2GLU0	Acinetobacter_phage	7.7e-35	46.9
WP_163762020.1\|2022927_2023338_+	hypothetical protein	K4IBX0	Acinetobacter_phage	1.2e-15	37.0
WP_163761869.1\|2023394_2023544_+	hypothetical protein	NA	NA	NA	NA
WP_163762021.1\|2023583_2025962_+	hypothetical protein	A0A1W6JPF2	Morganella_phage	5.8e-206	51.1
WP_163762022.1\|2026068_2026479_+	hypothetical protein	NA	NA	NA	NA
WP_163762023.1\|2026511_2027066_+	hypothetical protein	NA	NA	NA	NA
WP_163762024.1\|2027205_2028279_+	N-acetyltransferase	Q6SE88	Lactobacillus_prophage	1.1e-63	40.1
WP_140182660.1\|2028256_2028646_+	ASCH domain-containing protein	Q6SE87	Lactobacillus_prophage	3.2e-29	49.6
WP_163762025.1\|2029445_2029718_+	hypothetical protein	A0A1X9SFF3	Acinetobacter_phage	3.4e-17	47.7
WP_163762026.1\|2029707_2030595_+	hypothetical protein	A0A1X9SFF0	Acinetobacter_phage	2.5e-69	47.6
WP_163762027.1\|2030581_2031268_+\|plate	phage baseplate protein	A0A2R3UAK1	Myoviridae_environmental_samples	3.9e-30	40.6
WP_163762028.1\|2031269_2031623_+	hypothetical protein	K4IBY0	Acinetobacter_phage	6.5e-29	51.3
WP_163762029.1\|2031619_2032810_+	hypothetical protein	E2GM17	Acinetobacter_phage	1.8e-86	44.0
WP_163762030.1\|2032809_2033442_+	DUF2612 domain-containing protein	K4HYS2	Acinetobacter_phage	7.5e-44	46.6
WP_163762031.1\|2033449_2034712_+	hypothetical protein	A0A068CGF5	Acinetobacter_phage	1.5e-22	33.2
WP_163762244.1\|2034901_2035366_+\|tail	tail fiber assembly protein	B6SCW7	Bacteriophage	6.5e-29	49.6

DBSCAN-SWA_5

2796692 : 2849023

Leptospira_phage(15.38%)

holin,lysis,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004918982.1\|2796692_2797043_-\|holin	holin	NA	NA	NA	NA
WP_004918978.1\|2797902_2798697_-	type I methionyl aminopeptidase	NA	NA	NA	NA
WP_036943836.1\|2798689_2798896_-	ParD-like family protein	NA	NA	NA	NA
WP_163762056.1\|2799217_2799643_+	universal stress protein	A0A1W6JNV4	Morganella_phage	3.5e-29	47.9
WP_004918973.1\|2800105_2800420_+	nitrite reductase small subunit NirD	NA	NA	NA	NA
WP_004918964.1\|2800422_2800731_+	hypothetical protein	NA	NA	NA	NA
WP_163762057.1\|2800795_2801833_+	aromatic ring-hydroxylating dioxygenase subunit alpha	NA	NA	NA	NA
WP_004918960.1\|2801825_2802581_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_088499354.1\|2802633_2803389_+	IclR family transcriptional regulator	NA	NA	NA	NA
WP_104873410.1\|2803499_2804426_+	glyoxalase	NA	NA	NA	NA
WP_004918952.1\|2804430_2805645_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_072502201.1\|2805667_2806939_+	MFS transporter	NA	NA	NA	NA
WP_004918950.1\|2806969_2807488_+	cupin domain-containing protein	NA	NA	NA	NA
WP_104873409.1\|2807503_2808343_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_014658164.1\|2808357_2809152_+	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	8.3e-08	26.3
WP_104873408.1\|2809162_2809957_+	aspartate dehydrogenase	NA	NA	NA	NA
WP_104873407.1\|2809970_2811440_+	aldehyde dehydrogenase	NA	NA	NA	NA
WP_104873406.1\|2811508_2813152_+	thiamine pyrophosphate-binding protein	NA	NA	NA	NA
WP_004918937.1\|2814175_2814607_+	hypothetical protein	NA	NA	NA	NA
WP_004918928.1\|2814626_2815382_-	energy transducer TonB	NA	NA	NA	NA
WP_104873405.1\|2815430_2818430_-	TonB-dependent receptor	NA	NA	NA	NA
WP_104873404.1\|2818447_2819908_-	DUF560 domain-containing protein	NA	NA	NA	NA
WP_104873403.1\|2819975_2820740_-	hypothetical protein	NA	NA	NA	NA
WP_036943814.1\|2822084_2822450_+	DUF305 domain-containing protein	A0A218MND9	uncultured_virus	1.0e-13	74.5
WP_036943812.1\|2822575_2823049_-	membrane protein	NA	NA	NA	NA
WP_004918910.1\|2823947_2824244_-	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_163762248.1\|2824431_2824974_+	sulfatase-like hydrolase/transferase	NA	NA	NA	NA
WP_004918906.1\|2825310_2825475_+	hypothetical protein	NA	NA	NA	NA
WP_101495226.1\|2826120_2827229_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	5.2e-40	39.2
WP_004918896.1\|2827992_2828220_+	HEAT repeat domain-containing protein	NA	NA	NA	NA
WP_053110723.1\|2828795_2829575_-	elongation factor Tu	NA	NA	NA	NA
WP_004918885.1\|2829969_2830464_+	hypothetical protein	NA	NA	NA	NA
WP_014658149.1\|2831136_2831787_-	DUF4431 domain-containing protein	NA	NA	NA	NA
WP_014658148.1\|2832517_2833513_+	chitinase	NA	NA	NA	NA
WP_036943804.1\|2834299_2834902_-	thiamine biosynthesis protein ThiJ	NA	NA	NA	NA
WP_163762058.1\|2835497_2835836_+	hypothetical protein	NA	NA	NA	NA
WP_060561331.1\|2837586_2838243_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_163762249.1\|2838760_2840536_+	replication endonuclease	M1SV59	Escherichia_phage	1.4e-135	54.2
WP_163762059.1\|2840688_2842467_+	AIPR family protein	D0UIM0	Aggregatibacter_phage	3.5e-78	33.8
WP_163762060.1\|2842884_2843972_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	2.4e-42	38.0
WP_163762061.1\|2845069_2845498_-\|lysis	lysis protein	M1FJ79	Enterobacteria_phage	2.5e-14	35.9
WP_014658135.1\|2845516_2845909_-	M15 family metallopeptidase	A0A1P8DTE2	Proteus_phage	2.7e-44	86.2
WP_105874340.1\|2845901_2846150_-\|holin	holin	F1C5D1	Cronobacter_phage	1.0e-20	56.1
WP_120752678.1\|2846360_2846480_-	hypothetical protein	NA	NA	NA	NA
WP_014658133.1\|2846664_2846997_+	hypothetical protein	NA	NA	NA	NA
WP_163762062.1\|2847329_2847806_-	DUF1643 domain-containing protein	A0A142F2K6	Mycobacterium_phage	2.2e-16	36.9
WP_163762063.1\|2847842_2848622_-	antitermination protein	F1C595	Cronobacter_phage	3.7e-69	51.2
WP_141173636.1\|2848666_2849023_-	DUF968 domain-containing protein	A0A1I9KFA7	Aeromonas_phage	4.0e-34	67.7

DBSCAN-SWA_6

3168073 : 3236443

Salmonella_phage(17.95%)

tail,holin,coat,terminase,tRNA,lysis,head

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004918152.1\|3168073_3168862_-\|tRNA	tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM	NA	NA	NA	NA
WP_036943618.1\|3169266_3170094_+	envelope biogenesis factor ElyC	NA	NA	NA	NA
WP_014657931.1\|3170165_3170909_-	3-deoxy-manno-octulosonate cytidylyltransferase	NA	NA	NA	NA
WP_004918148.1\|3170914_3171094_-	hypothetical protein	NA	NA	NA	NA
WP_004918147.1\|3171239_3171455_-	cold shock domain-containing protein	A0A2H4N7Y6	Lake_Baikal_phage	1.2e-06	41.9
WP_004918145.1\|3171845_3172844_-	tetraacyldisaccharide 4'-kinase	NA	NA	NA	NA
WP_004918144.1\|3172840_3174586_-	lipid A ABC transporter ATP-binding protein/permease MsbA	W8CYL7	Bacillus_phage	2.4e-60	30.3
WP_163762098.1\|3174621_3176955_-	DNA internalization-related competence protein ComEC/Rec2	NA	NA	NA	NA
WP_004918141.1\|3177567_3177855_-	integration host factor subunit beta	A7KV42	Bacillus_phage	1.9e-10	40.0
WP_014657928.1\|3177910_3179584_-	30S ribosomal protein S1	NA	NA	NA	NA
WP_004918139.1\|3179760_3180444_-	(d)CMP kinase	NA	NA	NA	NA
WP_004918138.1\|3180646_3181921_-	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_004918137.1\|3182025_3183114_-	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	1.4e-82	46.4
WP_004918135.1\|3183413_3185048_-	alpha-D-glucose phosphate-specific phosphoglucomutase	NA	NA	NA	NA
WP_004918133.1\|3185109_3185658_-	replication initiation negative regulator SeqA	NA	NA	NA	NA
WP_072502949.1\|3185968_3186751_+	esterase	A0A2P1CHW5	Mycobacterium_phage	6.5e-05	31.1
WP_163762099.1\|3186982_3189070_+	type I secretion system permease/ATPase	W8CYL7	Bacillus_phage	2.4e-30	27.4
WP_102780678.1\|3189069_3190416_+	HlyD family type I secretion periplasmic adaptor subunit	NA	NA	NA	NA
WP_163762100.1\|3190419_3192360_+	type I secretion system permease/ATPase	W8CYL7	Bacillus_phage	1.5e-42	28.1
WP_004915371.1\|3192558_3192819_+	hypothetical protein	NA	NA	NA	NA
WP_163762101.1\|3192892_3194236_-	hypothetical protein	A0A1S6KUV1	Providencia_phage	2.8e-56	40.4
WP_163762102.1\|3194300_3198710_-	DUF1983 domain-containing protein	Q7Y3Z3	Yersinia_phage	1.4e-192	49.9
WP_163762103.1\|3198710_3199109_-	hypothetical protein	A0A059VK01	Pseudomonas_phage	4.7e-36	51.5
WP_163762104.1\|3199485_3199719_-	hypothetical protein	NA	NA	NA	NA
WP_163762105.1\|3199730_3200315_-	hypothetical protein	S4TND4	Salmonella_phage	1.9e-49	50.8
WP_163762106.1\|3200314_3200911_-	hypothetical protein	S4TSP7	Salmonella_phage	4.3e-57	54.6
WP_163762107.1\|3200914_3204349_-\|tail	phage tail tape measure protein	A0A0P0ZCJ4	Stx2-converting_phage	8.3e-36	24.1
WP_163762108.1\|3204468_3204855_-	hypothetical protein	NA	NA	NA	NA
WP_163762109.1\|3204961_3205108_-	hypothetical protein	NA	NA	NA	NA
WP_163762110.1\|3205117_3205387_-	hypothetical protein	NA	NA	NA	NA
WP_163762111.1\|3206618_3206909_-	hypothetical protein	NA	NA	NA	NA
WP_163762112.1\|3206975_3207473_-	hypothetical protein	NA	NA	NA	NA
WP_105874200.1\|3207591_3208170_-	zinc ribbon domain-containing protein	I6PDJ9	Cronobacter_phage	3.3e-22	56.8
WP_163762113.1\|3208278_3209427_-	hypothetical protein	NA	NA	NA	NA
WP_104873312.1\|3209427_3210630_-	hypothetical protein	NA	NA	NA	NA
WP_163762253.1\|3210896_3211376_-	type II toxin-antitoxin system death-on-curing family toxin	NA	NA	NA	NA
WP_104873311.1\|3211388_3211568_-	hypothetical protein	NA	NA	NA	NA
WP_072502332.1\|3211700_3212072_-	hypothetical protein	E7C9U7	Salmonella_phage	3.4e-36	65.7
WP_146778601.1\|3212184_3212379_-	hypothetical protein	NA	NA	NA	NA
WP_113532836.1\|3212516_3212951_-	hypothetical protein	NA	NA	NA	NA
WP_163762114.1\|3213005_3213941_-	hypothetical protein	A0A059VG08	Pseudomonas_phage	4.2e-59	42.8
WP_115113580.1\|3213952_3214348_-	electron transfer flavoprotein subunit beta	NA	NA	NA	NA
WP_004916411.1\|3214344_3214731_-	hypothetical protein	A0A059VF88	Pseudomonas_phage	1.8e-19	41.9
WP_004916412.1\|3214730_3215093_-	hypothetical protein	A0A0R6PH70	Moraxella_phage	2.5e-15	41.5
WP_163762115.1\|3215094_3215478_-	hypothetical protein	A0A0P0IVQ3	Acinetobacter_phage	9.8e-31	54.3
WP_104873307.1\|3215483_3215765_-	hypothetical protein	NA	NA	NA	NA
WP_104873306.1\|3215803_3216781_-\|coat	phage coat protein	A0A2H4JIE6	uncultured_Caudovirales_phage	4.6e-141	73.8
WP_014657897.1\|3216784_3217507_-	hypothetical protein	A0A0P0J090	Acinetobacter_phage	8.0e-66	55.7
WP_163762116.1\|3217873_3218983_-\|head	phage head morphogenesis protein	A0A0D4DBL9	Acinetobacter_phage	1.3e-107	54.1
WP_104873305.1\|3218963_3220331_-	DUF4055 domain-containing protein	A0A0P0IDW1	Acinetobacter_phage	1.0e-178	67.7
WP_115113583.1\|3220340_3221582_-\|terminase	PBSX family phage terminase large subunit	H6WRS9	Salmonella_phage	5.7e-189	77.6
WP_163762117.1\|3221562_3221964_-	hypothetical protein	B6SD32	Bacteriophage	2.1e-39	77.1
WP_163762118.1\|3222121_3222634_-	DNA-binding protein	A0A0P0ZBU2	Stx2-converting_phage	7.5e-26	38.3
WP_004921257.1\|3223112_3223346_+	HEAT repeat domain-containing protein	NA	NA	NA	NA
WP_148271229.1\|3223347_3223755_-\|lysis	lysis protein	A0A1P8DTG0	Proteus_phage	5.9e-26	50.8
WP_004918418.1\|3223801_3224134_-	M15 family peptidase	F1BUL3	Cronobacter_phage	5.1e-36	72.3
WP_004918415.1\|3224120_3224414_-\|holin	phage holin family protein	NA	NA	NA	NA
WP_004916901.1\|3224410_3224800_-	membrane protein	S4TRS4	Salmonella_phage	4.2e-13	35.0
WP_150376625.1\|3224949_3225192_+	hypothetical protein	NA	NA	NA	NA
WP_163762119.1\|3225195_3225387_-	hypothetical protein	NA	NA	NA	NA
WP_014657887.1\|3225573_3225822_-	hypothetical protein	NA	NA	NA	NA
WP_163762120.1\|3226728_3227232_-	DUF1133 family protein	A0A1P8DTF1	Proteus_phage	4.2e-66	73.1
WP_163762121.1\|3227246_3227444_-	hypothetical protein	NA	NA	NA	NA
WP_163762122.1\|3227433_3228027_-	recombination protein NinG	E7C9S3	Salmonella_phage	6.1e-80	80.1
WP_161750380.1\|3227998_3228142_-	hypothetical protein	A0A1P8DTE6	Proteus_phage	1.3e-17	89.4
WP_058336240.1\|3228138_3228801_-	serine/threonine protein phosphatase	K7P721	Enterobacteria_phage	1.6e-73	62.3
WP_163762123.1\|3228797_3229010_-	hypothetical protein	NA	NA	NA	NA
WP_104873295.1\|3229006_3229348_-	hypothetical protein	NA	NA	NA	NA
WP_163762124.1\|3229344_3229788_-	hypothetical protein	A0A1P8DTD8	Proteus_phage	5.8e-27	80.8
WP_136134165.1\|3229801_3230020_-	hypothetical protein	NA	NA	NA	NA
WP_163762125.1\|3230012_3230201_-	hypothetical protein	NA	NA	NA	NA
WP_036943309.1\|3230294_3230498_-	hypothetical protein	NA	NA	NA	NA
WP_036943306.1\|3230496_3231153_+	DUF4145 domain-containing protein	V5URE2	Shigella_phage	1.4e-56	51.4
WP_163762126.1\|3231475_3231742_-	hypothetical protein	NA	NA	NA	NA
WP_163762127.1\|3231742_3233137_-	AAA family ATPase	Q9MCT4	Escherichia_phage	8.3e-120	48.1
WP_113532792.1\|3234285_3234633_-	hypothetical protein	NA	NA	NA	NA
WP_163762128.1\|3234744_3234963_-	helix-turn-helix domain-containing protein	A0A2D1GLN0	Escherichia_phage	1.9e-18	66.7
WP_163762129.1\|3235070_3235799_+	helix-turn-helix transcriptional regulator	A0A2H4FNG6	Salmonella_phage	3.6e-58	53.8
WP_004916513.1\|3236101_3236443_+	DUF3024 domain-containing protein	A0A1W6JP12	Morganella_phage	1.8e-36	59.3

DBSCAN-SWA_7

3239972 : 3249564

Proteus_phage(27.27%)

integrase

attL 3247513:3247527|attR 3253456:3253470

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_163762134.1\|3239972_3240275_+	regulator	M9P0E2	Enterobacteria_phage	4.0e-27	59.2
WP_104873283.1\|3240382_3240613_+	hypothetical protein	NA	NA	NA	NA
WP_163761870.1\|3240602_3240818_+	hypothetical protein	A0A1P8DTG4	Proteus_phage	8.5e-16	62.3
WP_163762135.1\|3240814_3241027_+	hypothetical protein	NA	NA	NA	NA
WP_163761871.1\|3241028_3241322_+	hypothetical protein	A0A249XWT3	Proteus_phage	8.0e-17	52.4
WP_163762136.1\|3241386_3241578_+	DUF551 domain-containing protein	NA	NA	NA	NA
WP_163762137.1\|3241828_3242101_+	hypothetical protein	NA	NA	NA	NA
WP_163762138.1\|3242097_3242313_+	hypothetical protein	NA	NA	NA	NA
WP_163762139.1\|3242327_3243062_+	phage recombination protein Bet	A0A1I9LJN0	Stx_converting_phage	1.1e-65	67.6
WP_163762140.1\|3243021_3243657_+	YqaJ viral recombinase family protein	A0A0S2SY31	Pseudomonas_phage	3.1e-53	55.8
WP_163762254.1\|3243884_3244193_+	HNH endonuclease	K7ZJS8	Xanthomonas_citri_phage	5.7e-21	52.1
WP_163762141.1\|3244182_3244683_+	single-stranded DNA-binding protein	C6ZR36	Salmonella_phage	5.4e-53	58.3
WP_163762142.1\|3244696_3244882_+	hook protein	NA	NA	NA	NA
WP_163762143.1\|3245297_3245813_+	hypothetical protein	R9VWB9	Serratia_phage	1.9e-13	28.9
WP_163762144.1\|3245812_3246148_+	hypothetical protein	NA	NA	NA	NA
WP_163762145.1\|3246157_3246421_+	hypothetical protein	NA	NA	NA	NA
WP_163762146.1\|3246576_3246786_+	hypothetical protein	NA	NA	NA	NA
WP_163762147.1\|3246945_3247278_+	DUF2591 domain-containing protein	A0A1P8DTH6	Proteus_phage	1.0e-15	50.9
WP_163762148.1\|3247264_3247897_+	DNA methyltransferase	G8C7S6	Escherichia_phage	2.3e-61	60.8
3247513:3247527	attL	NA	NA	NA	NA
WP_146117213.1\|3248070_3248316_+	hypothetical protein	NA	NA	NA	NA
WP_163762149.1\|3248517_3249564_+\|integrase	site-specific integrase	G8C7S0	Escherichia_phage	6.1e-59	37.6
3253456:3253470	attR	NA	NA	NA	NA

DBSCAN-SWA_8

3278996 : 3289692

Organic_Lake_phycodnavirus(16.67%)

tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014657832.1\|3278996_3280763_+	cysteine/glutathione ABC transporter permease/ATP-binding protein CydD	F2Y302	Organic_Lake_phycodnavirus	1.4e-15	32.8
WP_014657831.1\|3280765_3282508_+	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	W8CYL7	Bacillus_phage	5.9e-22	24.9
WP_163762150.1\|3282516_3283218_+\|tRNA	leucyl/phenylalanyl-tRNA--protein transferase	NA	NA	NA	NA
WP_004244560.1\|3283358_3283577_+	translation initiation factor IF-1	NA	NA	NA	NA
WP_004918072.1\|3283643_3285929_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	8.4e-170	42.9
WP_004918070.1\|3285959_3286280_-\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	1.7e-15	48.4
WP_004918068.1\|3286663_3286915_+	cold shock domain-containing protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	1.3e-15	56.7
WP_014657829.1\|3287018_3287957_-	DUF1177 domain-containing protein	NA	NA	NA	NA
WP_004918066.1\|3288100_3288850_-	IclR family transcriptional regulator	NA	NA	NA	NA
WP_014657828.1\|3288846_3289692_-	hypothetical protein	M1I6H3	Paramecium_bursaria_Chlorella_virus	1.8e-21	30.6

DBSCAN-SWA_9

3334433 : 3342435

Escherichia_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014657808.1\|3334433_3335015_-	dCTP deaminase	I4AZP2	Saccharomonospora_phage	5.7e-30	41.1
WP_004917981.1\|3335066_3335711_-	uridine kinase	A0A1V0SAA3	Catovirus	1.4e-37	41.2
WP_104873355.1\|3336593_3337127_-	dCTP deaminase	I4AZP2	Saccharomonospora_phage	3.9e-17	31.6
WP_104873354.1\|3337375_3337585_-	uridine kinase	NA	NA	NA	NA
WP_004917969.1\|3337893_3338466_-	Tat proofreading chaperone DmsD	A0A077SLS7	Escherichia_phage	1.1e-17	40.0
WP_104873353.1\|3338477_3339380_-	dimethyl sulfoxide reductase anchor subunit	NA	NA	NA	NA
WP_014657804.1\|3339376_3340018_-	dimethylsulfoxide reductase subunit B	A0A077SL61	Escherichia_phage	4.7e-62	57.0
WP_104873351.1\|3340014_3342435_-	molybdopterin-dependent oxidoreductase	A0A077SK27	Escherichia_phage	1.5e-140	38.7

DBSCAN-SWA_10

3518804 : 3529396

Mycobacterium_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004917615.1\|3518804_3520013_+	D-alanyl-D-alanine carboxypeptidase DacA	B6DZZ7	Stx2-converting_phage	8.8e-110	50.9
WP_004917614.1\|3520112_3520376_+	YbeD family protein	NA	NA	NA	NA
WP_014657709.1\|3520635_3521280_+	lipoyl(octanoyl) transferase LipB	NA	NA	NA	NA
WP_004917612.1\|3521403_3522369_+	lipoyl synthase	NA	NA	NA	NA
WP_014657708.1\|3522511_3522721_-	transcription antiterminator/RNA stability regulator CspE	A0A1W6JNX5	Morganella_phage	7.7e-22	79.7
WP_004917609.1\|3522927_3523398_-	methylated-DNA--[protein]-cysteine S-methyltransferase	A0A2P1EL10	Moumouvirus	7.6e-17	35.7
WP_014657707.1\|3523688_3523916_+	glutaredoxin-like protein NrdH	V5UN81	Mycobacterium_phage	1.6e-17	56.2
WP_004917606.1\|3523925_3524339_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A142F1R4	Bacillus_phage	5.3e-14	41.9
WP_071599640.1\|3524349_3526482_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	V9VI16	Lactococcus_phage	4.4e-213	52.2
WP_004917602.1\|3526495_3527467_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A0M4S3B4	Mycobacterium_phage	1.6e-133	72.8
WP_061064333.1\|3528193_3529396_+	glycine betaine/L-proline ABC transporter ATP-binding protein ProV	G3M9Y6	Bacillus_virus	1.9e-27	36.8

DBSCAN-SWA_11

3926448 : 3981608

Stenotrophomonas_phage(14.29%)

transposase,integrase

attL 3925807:3925822|attR 3981818:3981833

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3925807:3925822	attL	NA	NA	NA	NA
WP_163762183.1\|3926448_3927714_-\|integrase	integrase arm-type DNA-binding domain-containing protein	B7SYF8	Stenotrophomonas_phage	3.9e-84	44.1
WP_094963069.1\|3928431_3928653_-	DUF987 family protein	NA	NA	NA	NA
WP_101495227.1\|3928661_3929144_-	DNA repair protein RadC	NA	NA	NA	NA
WP_163762184.1\|3929161_3929983_-	DUF945 domain-containing protein	K4F5L3	Cronobacter_phage	4.4e-44	36.5
WP_163762185.1\|3930078_3930378_-	antirestriction protein	NA	NA	NA	NA
WP_154611486.1\|3930576_3930795_-	hypothetical protein	NA	NA	NA	NA
WP_004916954.1\|3930861_3931326_-	hypothetical protein	NA	NA	NA	NA
WP_004916179.1\|3931397_3931895_-	hypothetical protein	NA	NA	NA	NA
WP_068908291.1\|3931911_3932601_-	transcriptional regulator	A0A0R6PH67	Moraxella_phage	1.1e-08	25.8
WP_163762186.1\|3932647_3933379_-	DUF3944 domain-containing protein	NA	NA	NA	NA
WP_004916159.1\|3933613_3934564_-	hypothetical protein	NA	NA	NA	NA
WP_042116133.1\|3934847_3935045_+	AlpA family phage regulatory protein	NA	NA	NA	NA
WP_163762259.1\|3935037_3936234_+	hypothetical protein	NA	NA	NA	NA
WP_129765245.1\|3938718_3940737_+	type VI secretion system tip protein VgrG	NA	NA	NA	NA
WP_129765242.1\|3940723_3941218_+	DUF4123 domain-containing protein	A4PE24	Ralstonia_virus	3.5e-20	38.2
WP_129765241.1\|3941214_3941553_+	hypothetical protein	NA	NA	NA	NA
WP_129765240.1\|3941554_3942256_+	hypothetical protein	NA	NA	NA	NA
WP_129765239.1\|3942265_3942973_+	hypothetical protein	NA	NA	NA	NA
WP_129765238.1\|3942988_3943249_+	PAAR domain-containing protein	A4JWV5	Burkholderia_virus	1.4e-12	46.8
WP_129765237.1\|3943217_3943454_+	hypothetical protein	NA	NA	NA	NA
WP_163762187.1\|3943647_3943902_-	hypothetical protein	NA	NA	NA	NA
WP_163762188.1\|3943955_3944189_-	helix-turn-helix domain-containing protein	A0A1B0VCD8	Salmonella_phage	4.7e-28	77.8
WP_129765235.1\|3944957_3945518_+	hypothetical protein	NA	NA	NA	NA
WP_070925360.1\|3945520_3945721_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_129949672.1\|3946143_3946464_+	hypothetical protein	NA	NA	NA	NA
WP_154611520.1\|3946594_3947029_-	Tat proofreading chaperone DmsD	A0A077SLS7	Escherichia_phage	2.5e-22	41.9
WP_129765410.1\|3947058_3947499_-	hypothetical protein	NA	NA	NA	NA
WP_121875320.1\|3947898_3948603_+\|transposase	IS6 family transposase	A0A077SL39	Escherichia_phage	1.3e-113	82.3
WP_094961085.1\|3949734_3950031_+	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_071547801.1\|3950072_3950372_+	IS66 family insertion sequence element accessory protein TnpB	S5VXZ8	Leptospira_phage	3.7e-17	47.3
WP_163762158.1\|3950456_3951980_+\|transposase	IS66 family transposase	S5VTD3	Leptospira_phage	2.0e-79	39.1
WP_163762189.1\|3952230_3954048_-	hypothetical protein	NA	NA	NA	NA
WP_163762190.1\|3954692_3954923_-	AlpA family transcriptional regulator	A0A1V0E8E5	Vibrio_phage	3.8e-06	42.9
WP_163762191.1\|3955023_3955617_-	inovirus Gp2 family protein	NA	NA	NA	NA
WP_121874908.1\|3956106_3957255_-	hypothetical protein	NA	NA	NA	NA
WP_121874907.1\|3958242_3959232_+	hypothetical protein	NA	NA	NA	NA
WP_121874906.1\|3959447_3960179_+	DUF3944 domain-containing protein	NA	NA	NA	NA
WP_068908291.1\|3960225_3960915_+	transcriptional regulator	A0A0R6PH67	Moraxella_phage	1.1e-08	25.8
WP_042116980.1\|3960931_3961429_+	hypothetical protein	NA	NA	NA	NA
WP_004916297.1\|3961432_3962320_+	hypothetical protein	NA	NA	NA	NA
WP_004917169.1\|3962706_3963144_+	antirestriction protein	NA	NA	NA	NA
WP_121874904.1\|3963204_3964026_+	DUF945 domain-containing protein	A0A2C9CX26	Yersinia_phage	8.0e-46	37.8
WP_101495227.1\|3964043_3964526_+	DNA repair protein RadC	NA	NA	NA	NA
WP_094963069.1\|3964534_3964756_+	DUF987 family protein	NA	NA	NA	NA
WP_121874903.1\|3965962_3967315_+	hypothetical protein	NA	NA	NA	NA
WP_121874902.1\|3967344_3968226_+	5'/3'-nucleotidase SurE	NA	NA	NA	NA
WP_121874901.1\|3969514_3970348_-	sugar-phosphatase	NA	NA	NA	NA
WP_121874900.1\|3970443_3971271_-	PRD domain-containing protein	NA	NA	NA	NA
WP_121874909.1\|3972593_3974000_+\|transposase	IS66 family transposase	NA	NA	NA	NA
WP_121874899.1\|3974472_3976374_+	PTS transporter subunit EIIC	NA	NA	NA	NA
WP_121874898.1\|3976391_3977873_+	glycoside hydrolase family 1 protein	NA	NA	NA	NA
WP_121874897.1\|3978074_3978359_+\|transposase	transposase	NA	NA	NA	NA
WP_121874896.1\|3978841_3979189_+	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_121874895.1\|3979249_3979708_-	copper resistance protein NlpE	NA	NA	NA	NA
WP_163762192.1\|3980342_3981608_+\|integrase	integrase arm-type DNA-binding domain-containing protein	B7SYF8	Stenotrophomonas_phage	7.9e-85	44.4
3981818:3981833	attR	NA	NA	NA	NA

DBSCAN-SWA_12

3992337 : 4060107

Escherichia_phage(29.41%)

tRNA,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004916000.1\|3992337_3992607_+\|transposase	transposase	NA	NA	NA	NA
WP_163762197.1\|3992543_3993349_-\|transposase	IS5 family transposase	A0A0M5M147	Mycobacterium_phage	1.3e-32	37.7
WP_036942853.1\|3994348_3994627_+	N-acetyltransferase	NA	NA	NA	NA
WP_014657413.1\|3994652_3995546_+	pirin family protein	NA	NA	NA	NA
WP_060561449.1\|3995670_3997242_-	AbgT family transporter	NA	NA	NA	NA
WP_004917323.1\|3997704_3998073_+	DUF1992 domain-containing protein	NA	NA	NA	NA
WP_104873198.1\|3998059_3998770_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_004917327.1\|3998839_3999175_-\|tRNA	tRNA-binding protein	NA	NA	NA	NA
WP_072502733.1\|3999466_4000024_+	NAD(P)H-dependent oxidoreductase	A0A2P0ZL77	Lactobacillus_phage	4.0e-17	36.5
WP_014657409.1\|4000152_4001202_-	spermidine/putrescine ABC transporter substrate-binding protein PotD	NA	NA	NA	NA
WP_004917333.1\|4001415_4002192_-	spermidine/putrescine ABC transporter permease PotC	NA	NA	NA	NA
WP_004917336.1\|4002188_4003052_-	spermidine/putrescine ABC transporter permease PotB	NA	NA	NA	NA
WP_004917339.1\|4003038_4004148_-	spermidine/putrescine ABC transporter ATP-binding protein PotA	G3M9Y6	Bacillus_virus	1.5e-31	35.5
WP_004917343.1\|4004932_4006579_+	fumarate hydratase	NA	NA	NA	NA
WP_004917347.1\|4006647_4007616_-	fimbrial protein	NA	NA	NA	NA
WP_014657408.1\|4007631_4008183_-	fimbrial protein	NA	NA	NA	NA
WP_004917351.1\|4008192_4008921_-	molecular chaperone	NA	NA	NA	NA
WP_104873197.1\|4008932_4011428_-	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_004917353.1\|4011637_4012198_-	fimbrial protein	NA	NA	NA	NA
WP_004917356.1\|4012319_4012622_-	helix-turn-helix transcriptional regulator	K4JNA7	Caulobacter_virus	1.1e-05	36.2
WP_004917359.1\|4013876_4014857_+	apolipoprotein N-acyltransferase	NA	NA	NA	NA
WP_004917362.1\|4014954_4015860_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004917363.1\|4015955_4017275_-	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_040132488.1\|4017535_4018150_-	Tat proofreading chaperone DmsD	A0A077SLS7	Escherichia_phage	4.0e-26	34.7
WP_004917367.1\|4018257_4019115_-	dimethyl sulfoxide reductase anchor subunit	A0A077SK59	Escherichia_phage	7.3e-26	35.9
WP_014657404.1\|4019116_4019734_-	dimethylsulfoxide reductase subunit B	A0A077SL61	Escherichia_phage	1.2e-73	59.1
WP_036942829.1\|4019745_4022190_-	molybdopterin-dependent oxidoreductase	A0A077SK27	Escherichia_phage	1.5e-217	51.0
WP_042116353.1\|4023309_4024563_+	MFS transporter	Q6JIH2	Burkholderia_virus	1.1e-35	26.7
WP_014657402.1\|4024637_4025687_-	osmoprotectant NAGGN system M42 family peptidase	NA	NA	NA	NA
WP_041705166.1\|4025691_4026462_-	FadR family transcriptional regulator	NA	NA	NA	NA
WP_060561453.1\|4026516_4027311_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	4.3e-12	30.1
WP_004917383.1\|4027307_4029110_-	dipeptide/oligopeptide/nickel ABC transporter permease/ATP-binding protein	G9BWD6	Planktothrix_phage	7.9e-22	31.7
WP_014657400.1\|4029106_4030054_-	ABC transporter permease	NA	NA	NA	NA
WP_004917390.1\|4030150_4031710_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_014657399.1\|4031860_4032508_+	DUF1028 domain-containing protein	NA	NA	NA	NA
WP_072502726.1\|4032931_4033369_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004917397.1\|4034423_4035845_+	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_004917400.1\|4036030_4036786_-	ATP-binding cassette domain-containing protein	W6JKT0	Anomala_cuprea_entomopoxvirus	7.2e-17	29.9
WP_004917402.1\|4036787_4037771_-	iron chelate uptake ABC transporter family permease subunit	NA	NA	NA	NA
WP_004917404.1\|4037757_4038720_-	iron chelate uptake ABC transporter family permease subunit	A0A2H4IY97	uncultured_Caudovirales_phage	9.0e-65	43.6
WP_004917406.1\|4038723_4039692_-	siderophore ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004917407.1\|4040450_4040792_+	hypothetical protein	NA	NA	NA	NA
WP_014657396.1\|4040988_4041285_+	DUF2645 family protein	NA	NA	NA	NA
WP_101495266.1\|4041979_4042330_+	hypothetical protein	NA	NA	NA	NA
WP_004917417.1\|4042333_4042690_+	thioredoxin family protein	A0A023NHA9	Dinoroseobacter_phage	1.2e-09	38.0
WP_014657394.1\|4042717_4044100_-	SPOR domain-containing protein	NA	NA	NA	NA
WP_104873195.1\|4045078_4046278_-	nicotinamide mononucleotide deamidase-related protein YfaY	NA	NA	NA	NA
WP_004917420.1\|4046543_4047197_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_004917421.1\|4047270_4048623_+	molecular chaperone	NA	NA	NA	NA
WP_004917422.1\|4048677_4050390_-	lysophospholipid acyltransferase family protein	NA	NA	NA	NA
WP_014657390.1\|4050860_4051445_-	HutD family protein	NA	NA	NA	NA
WP_004924658.1\|4052050_4053220_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A077SLN2	Escherichia_phage	1.3e-190	86.6
WP_004924660.1\|4053276_4053702_+\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	5.2e-25	50.4
WP_104873194.1\|4054535_4057073_-	penicillin acylase family protein	NA	NA	NA	NA
WP_036942803.1\|4057739_4058612_+	HNH endonuclease	NA	NA	NA	NA
WP_163762198.1\|4059019_4060107_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	5.8e-44	38.8

DBSCAN-SWA_13

4064130 : 4109300

Escherichia_phage(18.18%)

tRNA,transposase,integrase

attL 4094432:4094449|attR 4102574:4102591

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_072197236.1\|4064130_4064355_-\|transposase	transposase	NA	NA	NA	NA
WP_015422297.1\|4065423_4065990_-	hypothetical protein	NA	NA	NA	NA
WP_121875334.1\|4066058_4066301_-	hypothetical protein	NA	NA	NA	NA
WP_116672728.1\|4066297_4067005_-	WYL domain-containing protein	A0A0R6PH67	Moraxella_phage	5.1e-09	24.6
WP_116672727.1\|4067216_4068053_-	DUF945 domain-containing protein	A0A2C9CX26	Yersinia_phage	1.1e-45	38.1
WP_121875361.1\|4068154_4068589_-	antirestriction protein	NA	NA	NA	NA
WP_109396749.1\|4068828_4069254_-	antirestriction protein	NA	NA	NA	NA
WP_121875289.1\|4069345_4070218_-	GTP-binding protein	NA	NA	NA	NA
WP_163762200.1\|4070274_4071213_-	hypothetical protein	NA	NA	NA	NA
WP_121875291.1\|4071647_4072235_+	inovirus Gp2 family protein	NA	NA	NA	NA
WP_076914452.1\|4072340_4072550_+	AlpA family transcriptional regulator	NA	NA	NA	NA
WP_076914451.1\|4072620_4073208_+	hypothetical protein	NA	NA	NA	NA
WP_114143465.1\|4073250_4073947_+\|transposase	IS1 family transposase	A0A0U2RK18	Escherichia_phage	5.7e-61	46.8
WP_076914449.1\|4075211_4075988_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	2.1e-80	59.4
WP_014657437.1\|4076090_4076294_+\|transposase	transposase	NA	NA	NA	NA
WP_014657438.1\|4076485_4077838_+\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	4.9e-117	48.3
WP_076914448.1\|4077933_4078722_+\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	1.1e-47	38.6
WP_163762201.1\|4078768_4078990_+\|transposase	transposase	NA	NA	NA	NA
WP_076914447.1\|4080403_4080745_+	helix-turn-helix transcriptional regulator	A0A1W6JNW5	Morganella_phage	1.3e-05	46.4
WP_076914446.1\|4080810_4081341_+	type 1 fimbrial protein	NA	NA	NA	NA
WP_014657443.1\|4081417_4081954_+	type 1 fimbrial protein	NA	NA	NA	NA
WP_076914445.1\|4082054_4084724_+	outer membrane usher protein	NA	NA	NA	NA
WP_014657445.1\|4084776_4085553_+	fimbria/pilus periplasmic chaperone	NA	NA	NA	NA
WP_114143467.1\|4085630_4086209_+	type 1 fimbrial protein	NA	NA	NA	NA
WP_121875308.1\|4086218_4086758_+	fimbrial protein	NA	NA	NA	NA
WP_121875307.1\|4086773_4087271_+	fimbrial protein	NA	NA	NA	NA
WP_076914444.1\|4087281_4087779_+	fimbrial protein	NA	NA	NA	NA
WP_014657450.1\|4087775_4088300_+	fimbrial protein	NA	NA	NA	NA
WP_121875306.1\|4088324_4088867_+	type 1 fimbrial protein	NA	NA	NA	NA
WP_121875305.1\|4089155_4090052_+	hypothetical protein	NA	NA	NA	NA
WP_014657455.1\|4091197_4091500_+	acid-resistance protein	NA	NA	NA	NA
WP_076914431.1\|4091754_4092228_+	nucleoside deaminase	NA	NA	NA	NA
WP_121875348.1\|4092586_4092895_+	hypothetical protein	NA	NA	NA	NA
WP_148271239.1\|4093060_4093393_+	hypothetical protein	NA	NA	NA	NA
WP_121875353.1\|4094056_4094629_+	cytochrome b/b6 domain-containing protein	NA	NA	NA	NA
4094432:4094449	attL	NA	NA	NA	NA
WP_163762181.1\|4094956_4095136_+	hypothetical protein	NA	NA	NA	NA
WP_121875103.1\|4095954_4096539_-	antirestriction protein ArdA	A0A0A8WIV6	Clostridium_phage	3.8e-26	41.5
WP_121875102.1\|4096872_4097157_-	hypothetical protein	NA	NA	NA	NA
WP_121875101.1\|4097412_4098681_-\|integrase	integrase arm-type DNA-binding domain-containing protein	Q7M297	Enterobacteria_phage	6.3e-82	39.7
WP_163762202.1\|4099418_4100645_+	D-alanyl-D-alanine- carboxypeptidase/endopeptidase AmpH	NA	NA	NA	NA
WP_004915963.1\|4101237_4101660_+	hypothetical protein	NA	NA	NA	NA
WP_004915962.1\|4101739_4102816_-	LPS export ABC transporter permease LptG	NA	NA	NA	NA
4102574:4102591	attR	NA	NA	NA	NA
WP_004915961.1\|4102815_4103913_-	LPS export ABC transporter permease LptF	NA	NA	NA	NA
WP_004915960.1\|4104191_4105703_+	leucyl aminopeptidase	Q6GYZ8	Mycoplasma_phage	4.6e-47	37.6
WP_004915959.1\|4105942_4106392_+	DNA polymerase III subunit chi	NA	NA	NA	NA
WP_004915958.1\|4106405_4109300_+\|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	1.3e-138	36.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP048621

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection