CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_AP022605	Mycolicibacterium doricum strain JCM 12405	4 crisprs	cas3,csa3,RT,c2c9_V-U4,WYL,DEDDh,DinG	0	3	3	0

1. NZ_AP022605

CRISPR-Cas detection and classification

Crispr_ID: NZ_AP022605_1

• CRISPR_ID: NZ_AP022605_1
• CRISPR_location: 611613-611796
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NZ_AP022605_1

Consensus_repeat	Method
GGTGATCGTGTTGTTGGAGCCG	CRT

spacers of NZ_AP022605_1

>1.1|611635|32|NZ_AP022605|CRT
AGGTCTTCGATGTTCGGATCGCCGTCGGCGTA
>1.2|611689|32|NZ_AP022605|CRT
ACGACCGAGATCTCCTTGTCGACCCGGTCGAA
>1.3|611743|32|NZ_AP022605|CRT
CCGATGTTGACGTTCGCGCACGTCCCGGTCAC

CRISPR arrays and Neighbor proteins around NZ_AP022605_1

CRISPR arrays

The CRISPR arrays of NZ_AP022605_1

>merge|NZ_AP022605|1|611613-611796|CRT
GGTGATCGTGTTGTTGGAGCCGAGGTCTTCGATGTTCGGATCGCCGTCGGCGTAGGTGATCGTGTTGTTCAACCCGACGACCGAGATCTCCTTGTCGACCCGGTCGAAGGTGATCGTGTTGTCGGTGCCGCCGATGTTGACGTTCGCGCACGTCCCGGTCACCGTGATCGTGTTGTTGGAGCCG

>NZ_AP022605|1|1|611613-611796|CRT
GGTGATCGTGTTGTTGGAGCCG	AGGTCTTCGATGTTCGGATCGCCGTCGGCGTA
GGTGATCGTGTTGTTCAACCCG	ACGACCGAGATCTCCTTGTCGACCCGGTCGAA
GGTGATCGTGTTGTCGGTGCCG	CCGATGTTGACGTTCGCGCACGTCCCGGTCAC
CGTGATCGTGTTGTTGGAGCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP022605.1|WP_085192466.1|602307_603213_+|hypothetical-protein	unknown	unknown	unknown
NZ_AP022605.1|WP_011558404.1|615921_617112_+|elongation-factor-Tu	unknown	unknown	gnl|CDD|234596
NZ_AP022605.1|WP_085192421.1|621451_622051_-|mycofactocin-system-transcriptional-regulator	unknown	unknown	gnl|CDD|188483
NZ_AP022605.1|WP_011558402.1|613071_613542_+|30S-ribosomal-protein-S7	unknown	unknown	gnl|CDD|235398
NZ_AP022605.1|WP_085192428.1|610424_611591_+|iron-containing-alcohol-dehydrogenase	unknown	unknown	gnl|CDD|341473
NZ_AP022605.1|WP_085192430.1|608828_609575_+|PaaX-domain-containing-protein,-C--domain-protein	unknown	unknown	gnl|CDD|225864
NZ_AP022605.1|WP_085192434.1|604200_605298_+|phosphatase-PAP2-family-protein	unknown	unknown	gnl|CDD|379588
NZ_AP022605.1|WP_085192436.1|598213_602191_+|DNA-directed-RNA-polymerase-subunit-beta'	unknown	unknown	gnl|CDD|234794
NZ_AP022605.1|WP_085192422.1|620887_621412_-|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|274357
NZ_AP022605.1|WP_085192424.1|618384_619590_+|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|223523
NZ_AP022605.1|WP_085192426.1|613628_615743_+|elongation-factor-G	unknown	unknown	gnl|CDD|234569
NZ_AP022605.1|WP_085192435.1|603354_604104_+|deoxyribonuclease-IV	unknown	unknown	gnl|CDD|179214
NZ_AP022605.1|WP_085192425.1|617303_618137_-|universal-stress-protein	unknown	unknown	gnl|CDD|366180
NZ_AP022605.1|WP_011558401.1|612697_613072_+|30S-ribosomal-protein-S12	unknown	unknown	gnl|CDD|235355
NZ_AP022605.1|WP_085192432.1|606213_607842_+|acyl-CoA-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|173843
NZ_AP022605.1|WP_099050290.1|605384_606110_+|polyhydroxybutyrate-depolymerase	unknown	unknown	gnl|CDD|226040
NZ_AP022605.1|WP_085192431.1|607887_608826_+|crotonase/enoyl-CoA-hydratase-family-protein	unknown	unknown	gnl|CDD|236213
NZ_AP022605.1|WP_085192423.1|619619_620891_-|VOC-family-protein	unknown	unknown	gnl|CDD|319910
NZ_AP022605.1|WP_085192420.1|622143_622302_+|mycofactocin-precursor	unknown	unknown	gnl|CDD|274887
NZ_AP022605.1|WP_085192429.1|609571_610336_+|crotonase/enoyl-CoA-hydratase-family-protein	unknown	unknown	gnl|CDD|236205

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP022605.1|WP_011558404.1|615921_617112_+|elongation-factor-Tu	gnl|CDD|234596	PRK00049, PRK00049, elongation factor Tu; Reviewed.	0
NZ_AP022605.1|WP_085192421.1|621451_622051_-|mycofactocin-system-transcriptional-regulator	gnl|CDD|188483	TIGR03968, transcriptional_regulator_TetR_family, mycofactocin system transcriptional regulator. Members of this family are TetR family putative transcriptional regulators that occur in genome contexts near proteins of the mycofactocin system. These include the precursor peptide (TIGR03969), a radical SAM peptide maturase (TIGR03962), and a putative carrier protein (TIGR03967). [Regulatory functions, DNA interactions].	2.09582e-101
NZ_AP022605.1|WP_011558402.1|613071_613542_+|30S-ribosomal-protein-S7	gnl|CDD|235398	PRK05302, PRK05302, 30S ribosomal protein S7; Validated.	3.3407e-107
NZ_AP022605.1|WP_085192428.1|610424_611591_+|iron-containing-alcohol-dehydrogenase	gnl|CDD|341473	cd08194, Fe-ADH-like, Iron-containing alcohol dehydrogenases-like. This family contains iron-containing alcohol dehydrogenase (Fe-ADH) most of which have not been characterized. Their specific function is unknown. The protein structure represents a dehydroquinate synthase-like fold and belongs to the alcohol dehydrogenase-like superfamily. It is distinct from other alcohol dehydrogenases which contain different protein domains. Alcohol dehydrogenase catalyzes the reduction of acetaldehyde to alcohol with NADP as cofactor. Its activity requires iron ions.	0
NZ_AP022605.1|WP_085192430.1|608828_609575_+|PaaX-domain-containing-protein,-C--domain-protein	gnl|CDD|225864	COG3327, PaaX, Phenylacetic acid-responsive transcriptional repressor [Transcription].	5.28701e-63
NZ_AP022605.1|WP_085192434.1|604200_605298_+|phosphatase-PAP2-family-protein	gnl|CDD|379588	pfam14378, PAP2_3, PAP2 superfamily.	5.62369e-15
NZ_AP022605.1|WP_085192436.1|598213_602191_+|DNA-directed-RNA-polymerase-subunit-beta'	gnl|CDD|234794	PRK00566, PRK00566, DNA-directed RNA polymerase subunit beta'; Provisional.	0
NZ_AP022605.1|WP_085192422.1|620887_621412_-|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	2.00483e-24
NZ_AP022605.1|WP_085192424.1|618384_619590_+|NAD(P)/FAD-dependent-oxidoreductase	gnl|CDD|223523	COG0446, HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only].	1.16315e-64
NZ_AP022605.1|WP_085192426.1|613628_615743_+|elongation-factor-G	gnl|CDD|234569	PRK00007, PRK00007, elongation factor G; Reviewed.	0
NZ_AP022605.1|WP_085192435.1|603354_604104_+|deoxyribonuclease-IV	gnl|CDD|179214	PRK01060, PRK01060, endonuclease IV; Provisional.	8.70814e-113
NZ_AP022605.1|WP_085192425.1|617303_618137_-|universal-stress-protein	gnl|CDD|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	1.25378e-10
NZ_AP022605.1|WP_011558401.1|612697_613072_+|30S-ribosomal-protein-S12	gnl|CDD|235355	PRK05163, rpsL, 30S ribosomal protein S12; Validated.	1.74825e-82
NZ_AP022605.1|WP_085192432.1|606213_607842_+|acyl-CoA-dehydrogenase-family-protein	gnl|CDD|173843	cd01154, AidB, Proteins involved in DNA damage response, similar to the AidB gene product. AidB is one of several genes involved in the SOS adaptive response to DNA alkylation damage, whose expression is activated by the Ada protein. Its function has not been entirely elucidated; however, it is similar in sequence and function to acyl-CoA dehydrogenases. It has been proposed that aidB directly destroys DNA alkylating agents such as nitrosoguanidines (nitrosated amides) or their reaction intermediates.	1.15631e-165
NZ_AP022605.1|WP_099050290.1|605384_606110_+|polyhydroxybutyrate-depolymerase	gnl|CDD|226040	COG3509, LpqC, Poly(3-hydroxybutyrate) depolymerase [Secondary metabolites biosynthesis, transport, and catabolism].	2.74065e-62
NZ_AP022605.1|WP_085192431.1|607887_608826_+|crotonase/enoyl-CoA-hydratase-family-protein	gnl|CDD|236213	PRK08272, PRK08272, crotonase/enoyl-CoA hydratase family protein.	0
NZ_AP022605.1|WP_085192423.1|619619_620891_-|VOC-family-protein	gnl|CDD|319910	cd07246, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	9.81222e-30
NZ_AP022605.1|WP_085192420.1|622143_622302_+|mycofactocin-precursor	gnl|CDD|274887	TIGR03969, conserved_hypothetical_protein, mycofactocin precursor. Members of this protein family occur in Mycobacterium tuberculosis and many other Actinobacteria, as well as some delta-Proteobacteria (e.g. Geobacter uraniireducens), Firmicutes (Pelotomaculum thermopropionicum and Desulfotomaculum acetoxidans), and Chloroflexi (Thermomicrobium roseum DSM 5159 and Sphaerobacter thermophilus DSM 20745). Members sometimes are missed during gene model identification but always occur in the vicinity of radical SAM (rSAM) enzyme TIGR03962, which resembles several rSAM enzymes of peptide maturation (PqqE, AlbA). Species with this protein always carry members of unusual clades of nicotinoproteins that are restricted to mycofactocin-containing species and in which the NAD, when studied, has appeared non-exchangeable. It is proposed that the mature form of mycofactocin is a novel redox carrier for a segregated redox pool.	2.69119e-08
NZ_AP022605.1|WP_085192429.1|609571_610336_+|crotonase/enoyl-CoA-hydratase-family-protein	gnl|CDD|236205	PRK08259, PRK08259, crotonase/enoyl-CoA hydratase family protein.	4.61718e-164

Protein sequences

>NZ_AP022605.1|WP_085192428.1|610424_611591_+|iron-containing-alcohol-dehydrogenase
MVADIALPRLAKIGAGAITELGSVVAQLGIRRPVLVTDRYLDETGQAERLVKILQAEGADTAVFSGAVPDPTASSLTAGLDVVRGHDADGVIGFGGGSPMDTAKALAVLSANGGSISEYRAPGSYAGPALPVVAVPTTAGSGSDSTQFTVITDDETDEKMLCPGLSFLPIAIVVDFELTLSMPPRLTADTGVDALTHAIEAYVSRRASPFSDALALAAMTAISRHLRRAYADGADREARESMMLAATQAGMAFSNSSVALVHGMSRPIGGHFHVAHGLSNAMLLPAVTKFSVDAAVDRYADCAKAMGVVDDTTASRAAADALVDELTQLCADVEVPTPGSYGIDRAQWEDRLVTMADQALASGSPANNPRVPTHGEIVTLYREIFERP
>NZ_AP022605.1|WP_085192429.1|609571_610336_+|crotonase/enoyl-CoA-hydratase-family-protein
MTGPVRVERTGTVTTVIIDRPDARNAVNRPTAEALHEAFDDFDRDDSASVAVLWGDHGTFCAGADLKAFGTPDANAVHRSGPGPMGPTRMVLSKPVIAAISGYAVAGGLELALWCDLRVVEQDAVLGVFCRRWGVPLIDGGTVRLPRLIGQSRAMDLILTGRAVDAAEAHAIGLANRVVPKGRARQQAEELAAEIARFPQQCLRSDRLAALGQWGLPEAEAIDQEFASISRVKHEALEGAGRFAAGAGRHGASA
>NZ_AP022605.1|WP_085192430.1|608828_609575_+|PaaX-domain-containing-protein,-C--domain-protein
MRLTARSVVLSVLLGAHPAWATASELFSLTADFGIREPTVRVALTRMVGAGDLVRSADGYRLSERLLSRQRRQDEAINPRLRPWDGTWTMLVITSVGTDARTRAALRNALQDKRFAELREGVWLRPDNLDAGLPDDVADRARVLHARDDDPHGLAAHLWDLTGWADRGRRLLDDMEAARDIPARFVTAAAIVRHLLTDPVLPAELLPERWPGDELRTAYTGFAAELVERRDARLSDARLSDAQLMEAT
>NZ_AP022605.1|WP_085192431.1|607887_608826_+|crotonase/enoyl-CoA-hydratase-family-protein
MTHAIRPVDFDDLKTMTYEVTGRVARITFNRPEKGNAIVADTPLELSALVERADLDPDVHVILLSGRGEGFCAGFDLSAYAEGSSSAGGGSPYRDTVLSGRTQAINHLPDRPWDPMVDYQMMSRFVRGFSSLLHCDKPTVVKIHGYCVAGGTDIALHADQVIAAADAKIGYPPTRVWGVPAAGMWAHRLGDQRAKRLLLTGDCLTGRQAAEWGLAVEAPEPEDLDERTERLVERIAAVPVNQLIMVKLAMNSALLQQGVATSRMVSTVFDGIARHTPEGHAFVAQSREHGFREAVRQRDEPFGDHGRRASGV
>NZ_AP022605.1|WP_085192432.1|606213_607842_+|acyl-CoA-dehydrogenase-family-protein
MPDTHVVTNQVPPLVDHNPAASPVLTEALIREGGEWGLGEVTELGALSGSAQAQRWGELADRNRPVLHTHDRVGHRIDEVEYDPAYHELMRTAIGHGLHAAPWADDRAGAHVVRAAKTSVWTPEPGHICPISMTYAVVPALRFNPDLAAVYEPLLTSRVYDPELKVPATKAGITAGMSMTEKQGGSDVRAGTTQAVPNGDGSYSLTGHKWFTSAPMCDIFLVLAQAPGGLSCFLLPRILPDGARNRMLLQRLKDKLGNHANASSEVEYDGATAWLVGEEGRGVPTIIEMVNLTRLDCTLGSATSMRSGLTRAIHHAQHRKAFGEYLIDQPLMRNVLADLAVEGEAATMVAMRMAGATDRAVRGDSREALLRRIGLASAKYWVCKRATPHAAEAMECLGGNGYVEDSGMPRLYREAPLMGIWEGSGNVSALDTLRAMMTRPDSVEVLFDELAQVSGADPRLGVHVDGLKQALGDVETIQYRARKVAEDICLALQGALLVRHGHPAVAEAFLATRLDRRWGGAFGTLPAGLDLDPILERALVAV
>NZ_AP022605.1|WP_099050290.1|605384_606110_+|polyhydroxybutyrate-depolymerase
MGFAGLDRAYSLYIPDGVASPAPLVVMLHGGFGSAAQAERAYGWNQLADSAKFVVAYPDGITHAWNANGGCCGLPARQGIDDVGFITAVVNDISANISVDAERVFATGISNGGMMSYALACNTAVFAAIGPDAATQLDPCPAPRPTSVIHIHGTDDQLIRYDGQPGAGVARIDGPAVADLNAFWRNVDHCATPETTADGPVTTSIASCPDGRGVTLVTVDGGGHEWPPFATGTIWEFFAAH
>NZ_AP022605.1|WP_085192434.1|604200_605298_+|phosphatase-PAP2-family-protein
MSAVDQSSIALTPPDVMSGRRRLTLVRWAAIALWAVVVVYRTATDGFAFNRELVLLYIATGLMAASIGRGRRMLFVIRDWLPFALVLLAYDLSRGAATLIGRPTLWHWQADADRWLFFGAMPTVWLQERLKQPTPPWWEIGISSVYMSFFVLPYAIAGVLWLRNREEWKAFVRLFVGLNVAALMVYALFPAAPPWAAARCSAADVEGGPSGPRCMFRSARGVPDGGVLGSMQFSQDGANQWIERIVGRGWGKLNLHSATALLDAGQASVNLVAAIPSLHAGMTAAMAAFLWHRVHRGWRPVLVAYVLVMAFTLVYTAEHYVVDILLGWAFAAVAVFAVNRYEAVAQQSPNNGTLSMVQWLLGSWR
>NZ_AP022605.1|WP_085192435.1|603354_604104_+|deoxyribonuclease-IV
MLIGSHVRNDDPLAAAEADGADVVQFFLGDPQSWKKPKPREDAEALKASSIPRYVHAPYLINVASANNRVRIPSRKILQDTCDAAAEVGATAVIVHGGHADDQDMEAGFQRWVKALDRLETTVPVYLENTAGGVHAMARHFDTIGRLWDHIGDHGIGFCLDTCHAWAAGEALVDAVSRIKRITGRIDLVHCNDSRDAAGSGADRHANVGTGQIDPQLLVAVVQAADAPVICETSDDGRKDDIAFLREHV
>NZ_AP022605.1|WP_085192466.1|602307_603213_+|hypothetical-protein
MRRQHGGVFIDEIFAAHGGVATARALSAVMSRKTLAAQLRAGAIVRVWHGVYSLGPPDTLTKLAALDVLVGRPVVACLHTAADLHGFRTEASGPVHILDPGIRMRPTVGLMVHQRVGAPLQRVAAGRLVTTPAWTAVEIARTLSRPRALATLDAALHVQACGPADVARAVDEQKGRRGIVNVRALLTHIDSRAESPMESEARLVFIDGGLPKPELQYEIVDRCGQLWRADFAWPEARVLAEYDSMEWHANAVALRHDRMKTARLQECGWTVIPLVVDDVRRYPLDLVARIAAYLERADMAG
>NZ_AP022605.1|WP_085192436.1|598213_602191_+|DNA-directed-RNA-polymerase-subunit-beta'
MLDVNFFDELRIGLATADDIRQWSYGEVKKPETINYRTLKPEKDGLFCEKIFGPTRDWECYCGKYKRVRFKGIICERCGVEVTRAKVRRERMGHIELAAPVTHIWYFKGVPSRLGYLLDLAPKDLEKIIYFAAYVITDVNDEMRHNELSTLEAEMVVERKAVEDQRDADLEARAQKLEADLAELEAEGAKSDVRRKVRDGGEREMRQLRDRAQRELDRLDEIWTTFTKLAPKQLIVDEVLYRELVDRYGEYFTGAMGAESIKKLIENFDIEAEAENLRETIRSGKGQKKLRALKRLKVVAAFQSNANSPMGMVLDAVPVIPPELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLIDLGAPEIIVNNEKRMLQESVDALFDNGRRGRPVTGPGNRPLKSLSDLLKGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKLMALELFKPFVMKRLVDLNHAQNIKSAKRMVERQRPQVWDVLEEVISEHPVLLNRAPTLHRLGIQAFEPQLVEGKAIQLHPLVCEAFNADFDGDQMAVHLPLSAEAQAEARILMLSSNNILSPASGKPLAMPRLDMVTGLYFLTTMIEGDKGEYRAPSTDQPESGVYSSPAEAIMAMDRGALSVRAKIKVRLTQLRPPAALEAQLFPSDGESAGGWRPGDAWTAETTLGRVMFNELLPISYPFINEQMHKKVQARIINDLAERFPMIVVAQTVDKLKDAGFYWATRSGVTVSMADVLVPPQKQEILDRYEKEADGIERKYQRGALNHKERNDSLVKIWQDATEEVGKALEEHYPSDNPIITIVKSGATGNFTQTRTLAGMKGLVTNPKGEFIPRPIKSSFREGLTVLEYFINTHGARKGLADTALRTADSGYLTRRLVDVSQDVIVREHDCETERGINVTLAERAATLDGGAALIRDPHVETSAFARTLATDAVDADGNVVIQRGHDLGDPAIDKLLASGIDHVKVRSVLTCASASGVCAMCYGRSMATGKLVDIGEAVGIVAAQSIGEPGTQLTMRTFHQGGVGEDITGGLPRVQELFEARVPRNKAPIADVSGRVQLEEGERFYKITIVPDDGGEEVVYDKLSKRQRLRVIKHEDGTEGVLSDGDHVEVGDQLMEGSADPHEVLRVQGPREVQIHLVHEVQEVYRAQGVSIHDKHIEVIVRQMLRRVTIIDSGATEFLPGSLTERAEFESENRRVVAEGGEPAAGRPVLMGITKASLATDSWLSAASFQETTRVLTDAAINCRSDKLQGLKENVIIGKLIPAGTGINRYRNIQVQPTEEARAAAYTIPSYEDQYYSPDFGQATGAAVPLDDYGYSDYR
>NZ_AP022605.1|WP_011558401.1|612697_613072_+|30S-ribosomal-protein-S12
MPTINQLVRKGRRDKIAKVKTAALKGSPQRRGVCTRVYTTTPKKPNSALRKVARVKLTSQVEVTAYIPGEGHNLQEHSMVLVRGGRVKDLPGVRYKIIRGSLDTQGVKNRKQARSRYGAKKEKS
>NZ_AP022605.1|WP_011558402.1|613071_613542_+|30S-ribosomal-protein-S7
MPRKGPAPKRPLVNDPVYGSQLVTQLVNKVLLDGKKSLAERIVYGALEQARDKTGTDPVVTLKRALDNVKPALEVRSRRVGGATYQVPVEVRPDRSVTLALRWLVSFSKARREKTMVERLANEILDASNGLGAAVKRREDTHKMAEANRAFAHYRW
>NZ_AP022605.1|WP_085192426.1|613628_615743_+|elongation-factor-G
MAQKDVLTDLNKVRNIGIMAHIDAGKTTTTERILYYTGISYKIGEVHDGAATMDWMEQEQERGITITSAATTCFWNDNQINLIDTPGHVDFTVEVERSLRVLDGAVAVFDGKEGVEPQSEQVWRQADKYNVPRICFVNKMDKLGADFYFSVRTMEERLGANVIPIQLPIGSEGDFAGVVDLVEMKAKVWSAEAKLGEKYDVLELSSLPSDLQERAEEYRLKLIEAAAETDEALLEKYLGGEELTVEEIKGALRKLTISSEAYLVLCGSAFKNKGVQPMLDAVIDYLPSPLDVPPAEGHPPGKEDEVITRNPSVDEPFSALAFKVATHPFFGKLTYVRVYSGTVESGSQVINATKGKKERLGKLFQMHSNKENPVERASAGHIYAVIGLKDTTTGDTLSDPNQQIVLESMTFPDPVIEVAIEPKTKSDQEKLGTAIQKLAEEDPTFKVHQDDETGQTVIGGMGELHLDILVDRMRREFKVEANVGKPQVAYRETIRRPVEKVEFTHKKQTGGSGQFAKVIINLEPFHGEDGATYEFENKVTGGRIPREYIPSVDAGAQDAMQYGVLAGYPLVNIKVTLLDGAYHEVDSSEMAFKVAGSQALKKAAQAAQPVILEPIMAVEVTTPEDYMGEVIGDLNSRRGQIQAMEERAGARVVRAQVPLSEMFGYVGDLRSKTQGRANYSMVFDSYAEVPANVSKEIIAKATGQ
>NZ_AP022605.1|WP_011558404.1|615921_617112_+|elongation-factor-Tu
MAKAKFERTKPHVNIGTIGHVDHGKTTLTAAITKVLHDKYPELNESRAFDQIDNAPEERQRGITINISHVEYQTEKRHYAHVDAPGHADYIKNMITGAAQMDGAILVVAATDGPMPQTREHVLLARQVGVPYILVALNKADAVDDEELIELVEMEVRELLAAQDFDEDAPVVRVSALKALEGDEKWVKSVEELMDAVDESIPDPVRDTDRPFLMPVEDVFTITGRGTVVTGRVERGVVNVNEEVEIVGIRPGTTKTTVTGVEMFRKLLDQGQAGDNVGLLLRGIKREDVERGQVVVKPGTTTPHTEFDGQVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGVVTLPEGTEMVMPGDNTDISVKLIQPVAMDEGLRFAIREGGRTVGAGRVTKIHK
>NZ_AP022605.1|WP_085192425.1|617303_618137_-|universal-stress-protein
MPLGVLIGYDGSPAATAAIEVGGRLLPRAHAWVAQLWTPPFASEPLRRRLRAVVGSASELVERTELEGEREAQRIAAAGTTLARAAGLDAEPLVKRSWGGEGLVLAQLAEQVSADLVLVGSRGLGGAQALMGSVSDMAVHYASRPTLVAPAPMLTQEYDALTEGPVVVGWDGSGGARTALAAAQHLFPDREIVVVSVGQGITETPPEGLAAEHVDAPAGAGEHLVADALTGLAAHRRASAIVVGSRGQSAMCQVLLGSVARATLRAAHRPVLVVPGP
>NZ_AP022605.1|WP_085192424.1|618384_619590_+|NAD(P)/FAD-dependent-oxidoreductase
MYNHQVSTSGGIVIVGGGLAAARTAEQLRRSNYPGPVTIVSEEDHLPYDRPPLSKEVLRSETDDVTLKPAEFYREKDITVLLGTGAATVDTAGRKITLTDGREIGYDELVIATGLVPKRIPSFPDLTGIHVLRNFDQSLKLRQEAGSARRAVVIGAGFIGCEVAASLRKLGVEVVLVEPQPAPLASVLGRQIGGLVARLHRAEGVDVRCGVGVAEVKGQDVDGQQKVRSVVLSDGTEVQADIVVVGIGSRPATDWLEGSGIALDNGVVCDAEGRSSAPHVWAIGDVASWRDTVGNQVRVEHWSNVADQARVLVPAMLGQGVPGVVSVPYFWSDQYDVKIQCLGKPEADDTVHIVEDDGRKFLAYYERDGVVAGVVGGGMPAKVMKTRSKIANSAPIAEVLG
>NZ_AP022605.1|WP_085192423.1|619619_620891_-|VOC-family-protein
MNDHTDPLWVLHGDDLPVPPDPAFAARLRARLQSALRLPDHTEPDHTEGVEMSRTDTALAAVVARPAALPYLAVADARAAIDWYVDALGATPAGEPMMMDDGRIGHAELTLSGGVLYLADEFPELGLKAPAPEHVSVSLLLQVADTDAALRRAHDHGAHVQREPYDAHGSRTAAIIDPFGHRWMLSGPVTGAGTPIRHGDVGYVSLWTRDTERAAAFYGHVLGWTYDAATHEVTNTALPTGIFAGDGPATLFCCYAVDDLDRARQSIVAAGGTLGETTGHDFGTTQDATDPLGNRFAVFTPSRPTPRPALNGTGPGALSYITYEVGDSALFREFYGRVLSWTFDPGRIADGWQVNESHPMAGVAGGSARSATVPMWTVADVDDAVRRVREAGGSVLQQPHRQPYGLMAECVDDQGARFYLGQF
>NZ_AP022605.1|WP_085192422.1|620887_621412_-|sigma-70-family-RNA-polymerase-sigma-factor
MGVSAEPDGEDASRALLALYDDALPTVYGYFVRRCPDRGTAEDLTSETFLAAMDAARRGASVPISVPWLIGVARHKLADHYRRGSHRHAVAVADLPEPGEPVDGWDAELDRIVAESVLAQLPEHHRTVLALRYLDGCSVPECAELIGRTVHATEALLTRARRAFRSHYPEGGRP
>NZ_AP022605.1|WP_085192421.1|621451_622051_-|mycofactocin-system-transcriptional-regulator
MRQDSAPRVGRRRSTTRDHITDVALELFAARGFDEVSVDDVAAAAGIARRTLFRYYSSKSAIPWGHFDAHLDHMRHLFDDLDPTVPVDEALRGALLAFNHFGPEETTRHRQRMRVILETDALQAYSMTMYAGWRAVIAQFVAARTGVKAQDLVPQTVAWTMLGVALSAYEQWLADEAVSLAQALGDAFDTVRDGLRAVH
>NZ_AP022605.1|WP_085192420.1|622143_622302_+|mycofactocin-precursor
MEPNQHVIEGAAGAAQAATSDAATSDAATSENELVTETLVEEVSIDGMCGVY

Crispr_ID: NZ_AP022605_2

• CRISPR_ID: NZ_AP022605_2
• CRISPR_location: 615719-615825
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_AP022605_2

Consensus_repeat	Method
CATCGCGAAGGCGACGGGTCAGTAG	CRISPRCasFinder

spacers of NZ_AP022605_2

>2.1|615744|57|NZ_AP022605|CRISPRCasFinder
AGCTCCGACGGCCGCTTGCGGCCGAGGCGCGCCACTGAGCCGAAGCCGAGCAATGAG

CRISPR arrays and Neighbor proteins around NZ_AP022605_2

CRISPR arrays

The CRISPR arrays of NZ_AP022605_2

>merge|NZ_AP022605|2|615719-615825|CRISPRCasFinder
CATCGCGAAGGCGACGGGTCAGTAGAGCTCCGACGGCCGCTTGCGGCCGAGGCGCGCCACTGAGCCGAAGCCGAGCAATGAGCATCGCGAAGGCGACGGGCCAGTAG

>NZ_AP022605|2|1|615719-615825|CRISPRCasFinder
CATCGCGAAGGCGACGGGTCAGTAG	AGCTCCGACGGCCGCTTGCGGCCGAGGCGCGCCACTGAGCCGAAGCCGAGCAATGAG
CATCGCGAAGGCGACGGGCCAGTAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP022605.1|WP_085192418.1|622594_623800_+|mycofactocin-radical-SAM-maturase	unknown	unknown	gnl|CDD|188477
NZ_AP022605.1|WP_011558404.1|615921_617112_+|elongation-factor-Tu	unknown	unknown	gnl|CDD|234596
NZ_AP022605.1|WP_165756778.1|611603_612017_-|DUF3060-domain-containing-protein	unknown	unknown	gnl|CDD|371435
NZ_AP022605.1|WP_085192428.1|610424_611591_+|iron-containing-alcohol-dehydrogenase	unknown	unknown	gnl|CDD|341473
NZ_AP022605.1|WP_085192430.1|608828_609575_+|PaaX-domain-containing-protein,-C--domain-protein	unknown	unknown	gnl|CDD|225864
NZ_AP022605.1|WP_011558402.1|613071_613542_+|30S-ribosomal-protein-S7	unknown	unknown	gnl|CDD|235398
NZ_AP022605.1|WP_085192434.1|604200_605298_+|phosphatase-PAP2-family-protein	unknown	unknown	gnl|CDD|379588
NZ_AP022605.1|WP_085192424.1|618384_619590_+|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|223523
NZ_AP022605.1|WP_085192422.1|620887_621412_-|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|274357
NZ_AP022605.1|WP_085192421.1|621451_622051_-|mycofactocin-system-transcriptional-regulator	unknown	unknown	gnl|CDD|188483
NZ_AP022605.1|WP_085192419.1|622304_622598_+|mycofactocin-biosynthesis-chaperone-MftB	unknown	unknown	gnl|CDD|274886
NZ_AP022605.1|WP_085192425.1|617303_618137_-|universal-stress-protein	unknown	unknown	gnl|CDD|366180
NZ_AP022605.1|WP_011558401.1|612697_613072_+|30S-ribosomal-protein-S12	unknown	unknown	gnl|CDD|235355
NZ_AP022605.1|WP_085192432.1|606213_607842_+|acyl-CoA-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|173843
NZ_AP022605.1|WP_085192417.1|623802_624996_+|mycofactocin-biosynthesis-FMN-dependent-deaminase-MftD	unknown	unknown	gnl|CDD|274885
NZ_AP022605.1|WP_099050290.1|605384_606110_+|polyhydroxybutyrate-depolymerase	unknown	unknown	gnl|CDD|226040
NZ_AP022605.1|WP_085192429.1|609571_610336_+|crotonase/enoyl-CoA-hydratase-family-protein	unknown	unknown	gnl|CDD|236205
NZ_AP022605.1|WP_085192423.1|619619_620891_-|VOC-family-protein	unknown	unknown	gnl|CDD|319910
NZ_AP022605.1|WP_085192420.1|622143_622302_+|mycofactocin-precursor	unknown	unknown	gnl|CDD|274887
NZ_AP022605.1|WP_085192431.1|607887_608826_+|crotonase/enoyl-CoA-hydratase-family-protein	unknown	unknown	gnl|CDD|236213

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP022605.1|WP_085192418.1|622594_623800_+|mycofactocin-radical-SAM-maturase	gnl|CDD|188477	TIGR03962, mycofact_rSAM, mycofactocin radical SAM maturase. Members of this family are uncharacterized radical SAM proteins from the Mycobacterium tuberculosis and many other Actinobacteria, as well as some deltaproteobacteria (e.g. Geobacter uraniireducens), firmicutes (Pelotomaculum thermopropionicum and Desulfotomaculum acetoxidans), and Chloroflexi (Thermomicrobium roseum DSM 5159 and Sphaerobacter thermophilus DSM 20745). They resemble several characterized radical SAM enzymes of peptide modification (PqqE, AlbA), and are always found next to the proposed target, TIGR03969, the putative mycofactocin precursor. [Unknown function, Enzymes of unknown specificity].	0
NZ_AP022605.1|WP_011558404.1|615921_617112_+|elongation-factor-Tu	gnl|CDD|234596	PRK00049, PRK00049, elongation factor Tu; Reviewed.	0
NZ_AP022605.1|WP_165756778.1|611603_612017_-|DUF3060-domain-containing-protein	gnl|CDD|371435	pfam11259, DUF3060, Protein of unknown function (DUF3060). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed.	5.17487e-17
NZ_AP022605.1|WP_085192428.1|610424_611591_+|iron-containing-alcohol-dehydrogenase	gnl|CDD|341473	cd08194, Fe-ADH-like, Iron-containing alcohol dehydrogenases-like. This family contains iron-containing alcohol dehydrogenase (Fe-ADH) most of which have not been characterized. Their specific function is unknown. The protein structure represents a dehydroquinate synthase-like fold and belongs to the alcohol dehydrogenase-like superfamily. It is distinct from other alcohol dehydrogenases which contain different protein domains. Alcohol dehydrogenase catalyzes the reduction of acetaldehyde to alcohol with NADP as cofactor. Its activity requires iron ions.	0
NZ_AP022605.1|WP_085192430.1|608828_609575_+|PaaX-domain-containing-protein,-C--domain-protein	gnl|CDD|225864	COG3327, PaaX, Phenylacetic acid-responsive transcriptional repressor [Transcription].	5.28701e-63
NZ_AP022605.1|WP_011558402.1|613071_613542_+|30S-ribosomal-protein-S7	gnl|CDD|235398	PRK05302, PRK05302, 30S ribosomal protein S7; Validated.	3.3407e-107
NZ_AP022605.1|WP_085192434.1|604200_605298_+|phosphatase-PAP2-family-protein	gnl|CDD|379588	pfam14378, PAP2_3, PAP2 superfamily.	5.62369e-15
NZ_AP022605.1|WP_085192424.1|618384_619590_+|NAD(P)/FAD-dependent-oxidoreductase	gnl|CDD|223523	COG0446, HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only].	1.16315e-64
NZ_AP022605.1|WP_085192422.1|620887_621412_-|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	2.00483e-24
NZ_AP022605.1|WP_085192421.1|621451_622051_-|mycofactocin-system-transcriptional-regulator	gnl|CDD|188483	TIGR03968, transcriptional_regulator_TetR_family, mycofactocin system transcriptional regulator. Members of this family are TetR family putative transcriptional regulators that occur in genome contexts near proteins of the mycofactocin system. These include the precursor peptide (TIGR03969), a radical SAM peptide maturase (TIGR03962), and a putative carrier protein (TIGR03967). [Regulatory functions, DNA interactions].	2.09582e-101
NZ_AP022605.1|WP_085192419.1|622304_622598_+|mycofactocin-biosynthesis-chaperone-MftB	gnl|CDD|274886	TIGR03967, hypothetical_protein_FraEuI1cDRAFT_6405, putative mycofactocin binding protein MftB. Families TIGR03969 and TIGR03962 describe, respectively, the putative mycofactocin precursor and its cognate radical SAM peptide maturase. This small protein family appears in the same sporadically distributed cassette and may serve as a scaffolding protein during mycofactocin maturation or as a carrier protein for the mature product, a putative novel redox carrier. A feature of mycofactocin-encoding genomes is co-clustering with sets of NAD-binding oxidoreductases in which the NAD is not exchangeable. Therefore it is proposed that mature mycofactocin, bound by a member of this family as a carrier protein, docks with the nicotinoprotein to allow electron transfer. Mediation of electron transfer through this system would define a segregated redox pool. [Unknown function, General].	2.51319e-29
NZ_AP022605.1|WP_085192425.1|617303_618137_-|universal-stress-protein	gnl|CDD|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	1.25378e-10
NZ_AP022605.1|WP_011558401.1|612697_613072_+|30S-ribosomal-protein-S12	gnl|CDD|235355	PRK05163, rpsL, 30S ribosomal protein S12; Validated.	1.74825e-82
NZ_AP022605.1|WP_085192432.1|606213_607842_+|acyl-CoA-dehydrogenase-family-protein	gnl|CDD|173843	cd01154, AidB, Proteins involved in DNA damage response, similar to the AidB gene product. AidB is one of several genes involved in the SOS adaptive response to DNA alkylation damage, whose expression is activated by the Ada protein. Its function has not been entirely elucidated; however, it is similar in sequence and function to acyl-CoA dehydrogenases. It has been proposed that aidB directly destroys DNA alkylating agents such as nitrosoguanidines (nitrosated amides) or their reaction intermediates.	1.15631e-165
NZ_AP022605.1|WP_085192417.1|623802_624996_+|mycofactocin-biosynthesis-FMN-dependent-deaminase-MftD	gnl|CDD|274885	TIGR03966, actino_HemFlav, heme/flavin dehydrogenase, mycofactocin system. Members of this protein family possess an N-terminal heme-binding domain and C-terminal flavodehydrogenase domain, and share homology to yeast flavocytochrome b2, to E. coli L-lactate dehydrogenase [cytochrome], to (S)-mandelate dehydrogenase, etc. This enzyme appears only in the context of the mycofactocin system. Interestingly, it is absent from the four species detected so far with mycofactocin but without an F420 biosynthesis system.	0
NZ_AP022605.1|WP_099050290.1|605384_606110_+|polyhydroxybutyrate-depolymerase	gnl|CDD|226040	COG3509, LpqC, Poly(3-hydroxybutyrate) depolymerase [Secondary metabolites biosynthesis, transport, and catabolism].	2.74065e-62
NZ_AP022605.1|WP_085192429.1|609571_610336_+|crotonase/enoyl-CoA-hydratase-family-protein	gnl|CDD|236205	PRK08259, PRK08259, crotonase/enoyl-CoA hydratase family protein.	4.61718e-164
NZ_AP022605.1|WP_085192423.1|619619_620891_-|VOC-family-protein	gnl|CDD|319910	cd07246, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	9.81222e-30
NZ_AP022605.1|WP_085192420.1|622143_622302_+|mycofactocin-precursor	gnl|CDD|274887	TIGR03969, conserved_hypothetical_protein, mycofactocin precursor. Members of this protein family occur in Mycobacterium tuberculosis and many other Actinobacteria, as well as some delta-Proteobacteria (e.g. Geobacter uraniireducens), Firmicutes (Pelotomaculum thermopropionicum and Desulfotomaculum acetoxidans), and Chloroflexi (Thermomicrobium roseum DSM 5159 and Sphaerobacter thermophilus DSM 20745). Members sometimes are missed during gene model identification but always occur in the vicinity of radical SAM (rSAM) enzyme TIGR03962, which resembles several rSAM enzymes of peptide maturation (PqqE, AlbA). Species with this protein always carry members of unusual clades of nicotinoproteins that are restricted to mycofactocin-containing species and in which the NAD, when studied, has appeared non-exchangeable. It is proposed that the mature form of mycofactocin is a novel redox carrier for a segregated redox pool.	2.69119e-08
NZ_AP022605.1|WP_085192431.1|607887_608826_+|crotonase/enoyl-CoA-hydratase-family-protein	gnl|CDD|236213	PRK08272, PRK08272, crotonase/enoyl-CoA hydratase family protein.	0

Protein sequences

>NZ_AP022605.1|WP_011558402.1|613071_613542_+|30S-ribosomal-protein-S7
MPRKGPAPKRPLVNDPVYGSQLVTQLVNKVLLDGKKSLAERIVYGALEQARDKTGTDPVVTLKRALDNVKPALEVRSRRVGGATYQVPVEVRPDRSVTLALRWLVSFSKARREKTMVERLANEILDASNGLGAAVKRREDTHKMAEANRAFAHYRW
>NZ_AP022605.1|WP_011558401.1|612697_613072_+|30S-ribosomal-protein-S12
MPTINQLVRKGRRDKIAKVKTAALKGSPQRRGVCTRVYTTTPKKPNSALRKVARVKLTSQVEVTAYIPGEGHNLQEHSMVLVRGGRVKDLPGVRYKIIRGSLDTQGVKNRKQARSRYGAKKEKS
>NZ_AP022605.1|WP_165756778.1|611603_612017_-|DUF3060-domain-containing-protein
MPAHPPVRTAFAALAAAAAFTLAGCGAESDDTNTPTATAGSSGAQVEIGNTINYGSVGTTAEVDCADGKSLNVGGSNNTITVTGTCANVNIGGTDNTITFDRVDKEISVVGLNNTITYADGDPNIEDLGSNNTITKG
>NZ_AP022605.1|WP_085192428.1|610424_611591_+|iron-containing-alcohol-dehydrogenase
MVADIALPRLAKIGAGAITELGSVVAQLGIRRPVLVTDRYLDETGQAERLVKILQAEGADTAVFSGAVPDPTASSLTAGLDVVRGHDADGVIGFGGGSPMDTAKALAVLSANGGSISEYRAPGSYAGPALPVVAVPTTAGSGSDSTQFTVITDDETDEKMLCPGLSFLPIAIVVDFELTLSMPPRLTADTGVDALTHAIEAYVSRRASPFSDALALAAMTAISRHLRRAYADGADREARESMMLAATQAGMAFSNSSVALVHGMSRPIGGHFHVAHGLSNAMLLPAVTKFSVDAAVDRYADCAKAMGVVDDTTASRAAADALVDELTQLCADVEVPTPGSYGIDRAQWEDRLVTMADQALASGSPANNPRVPTHGEIVTLYREIFERP
>NZ_AP022605.1|WP_085192429.1|609571_610336_+|crotonase/enoyl-CoA-hydratase-family-protein
MTGPVRVERTGTVTTVIIDRPDARNAVNRPTAEALHEAFDDFDRDDSASVAVLWGDHGTFCAGADLKAFGTPDANAVHRSGPGPMGPTRMVLSKPVIAAISGYAVAGGLELALWCDLRVVEQDAVLGVFCRRWGVPLIDGGTVRLPRLIGQSRAMDLILTGRAVDAAEAHAIGLANRVVPKGRARQQAEELAAEIARFPQQCLRSDRLAALGQWGLPEAEAIDQEFASISRVKHEALEGAGRFAAGAGRHGASA
>NZ_AP022605.1|WP_085192430.1|608828_609575_+|PaaX-domain-containing-protein,-C--domain-protein
MRLTARSVVLSVLLGAHPAWATASELFSLTADFGIREPTVRVALTRMVGAGDLVRSADGYRLSERLLSRQRRQDEAINPRLRPWDGTWTMLVITSVGTDARTRAALRNALQDKRFAELREGVWLRPDNLDAGLPDDVADRARVLHARDDDPHGLAAHLWDLTGWADRGRRLLDDMEAARDIPARFVTAAAIVRHLLTDPVLPAELLPERWPGDELRTAYTGFAAELVERRDARLSDARLSDAQLMEAT
>NZ_AP022605.1|WP_085192431.1|607887_608826_+|crotonase/enoyl-CoA-hydratase-family-protein
MTHAIRPVDFDDLKTMTYEVTGRVARITFNRPEKGNAIVADTPLELSALVERADLDPDVHVILLSGRGEGFCAGFDLSAYAEGSSSAGGGSPYRDTVLSGRTQAINHLPDRPWDPMVDYQMMSRFVRGFSSLLHCDKPTVVKIHGYCVAGGTDIALHADQVIAAADAKIGYPPTRVWGVPAAGMWAHRLGDQRAKRLLLTGDCLTGRQAAEWGLAVEAPEPEDLDERTERLVERIAAVPVNQLIMVKLAMNSALLQQGVATSRMVSTVFDGIARHTPEGHAFVAQSREHGFREAVRQRDEPFGDHGRRASGV
>NZ_AP022605.1|WP_085192432.1|606213_607842_+|acyl-CoA-dehydrogenase-family-protein
MPDTHVVTNQVPPLVDHNPAASPVLTEALIREGGEWGLGEVTELGALSGSAQAQRWGELADRNRPVLHTHDRVGHRIDEVEYDPAYHELMRTAIGHGLHAAPWADDRAGAHVVRAAKTSVWTPEPGHICPISMTYAVVPALRFNPDLAAVYEPLLTSRVYDPELKVPATKAGITAGMSMTEKQGGSDVRAGTTQAVPNGDGSYSLTGHKWFTSAPMCDIFLVLAQAPGGLSCFLLPRILPDGARNRMLLQRLKDKLGNHANASSEVEYDGATAWLVGEEGRGVPTIIEMVNLTRLDCTLGSATSMRSGLTRAIHHAQHRKAFGEYLIDQPLMRNVLADLAVEGEAATMVAMRMAGATDRAVRGDSREALLRRIGLASAKYWVCKRATPHAAEAMECLGGNGYVEDSGMPRLYREAPLMGIWEGSGNVSALDTLRAMMTRPDSVEVLFDELAQVSGADPRLGVHVDGLKQALGDVETIQYRARKVAEDICLALQGALLVRHGHPAVAEAFLATRLDRRWGGAFGTLPAGLDLDPILERALVAV
>NZ_AP022605.1|WP_099050290.1|605384_606110_+|polyhydroxybutyrate-depolymerase
MGFAGLDRAYSLYIPDGVASPAPLVVMLHGGFGSAAQAERAYGWNQLADSAKFVVAYPDGITHAWNANGGCCGLPARQGIDDVGFITAVVNDISANISVDAERVFATGISNGGMMSYALACNTAVFAAIGPDAATQLDPCPAPRPTSVIHIHGTDDQLIRYDGQPGAGVARIDGPAVADLNAFWRNVDHCATPETTADGPVTTSIASCPDGRGVTLVTVDGGGHEWPPFATGTIWEFFAAH
>NZ_AP022605.1|WP_085192434.1|604200_605298_+|phosphatase-PAP2-family-protein
MSAVDQSSIALTPPDVMSGRRRLTLVRWAAIALWAVVVVYRTATDGFAFNRELVLLYIATGLMAASIGRGRRMLFVIRDWLPFALVLLAYDLSRGAATLIGRPTLWHWQADADRWLFFGAMPTVWLQERLKQPTPPWWEIGISSVYMSFFVLPYAIAGVLWLRNREEWKAFVRLFVGLNVAALMVYALFPAAPPWAAARCSAADVEGGPSGPRCMFRSARGVPDGGVLGSMQFSQDGANQWIERIVGRGWGKLNLHSATALLDAGQASVNLVAAIPSLHAGMTAAMAAFLWHRVHRGWRPVLVAYVLVMAFTLVYTAEHYVVDILLGWAFAAVAVFAVNRYEAVAQQSPNNGTLSMVQWLLGSWR
>NZ_AP022605.1|WP_011558404.1|615921_617112_+|elongation-factor-Tu
MAKAKFERTKPHVNIGTIGHVDHGKTTLTAAITKVLHDKYPELNESRAFDQIDNAPEERQRGITINISHVEYQTEKRHYAHVDAPGHADYIKNMITGAAQMDGAILVVAATDGPMPQTREHVLLARQVGVPYILVALNKADAVDDEELIELVEMEVRELLAAQDFDEDAPVVRVSALKALEGDEKWVKSVEELMDAVDESIPDPVRDTDRPFLMPVEDVFTITGRGTVVTGRVERGVVNVNEEVEIVGIRPGTTKTTVTGVEMFRKLLDQGQAGDNVGLLLRGIKREDVERGQVVVKPGTTTPHTEFDGQVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGVVTLPEGTEMVMPGDNTDISVKLIQPVAMDEGLRFAIREGGRTVGAGRVTKIHK
>NZ_AP022605.1|WP_085192425.1|617303_618137_-|universal-stress-protein
MPLGVLIGYDGSPAATAAIEVGGRLLPRAHAWVAQLWTPPFASEPLRRRLRAVVGSASELVERTELEGEREAQRIAAAGTTLARAAGLDAEPLVKRSWGGEGLVLAQLAEQVSADLVLVGSRGLGGAQALMGSVSDMAVHYASRPTLVAPAPMLTQEYDALTEGPVVVGWDGSGGARTALAAAQHLFPDREIVVVSVGQGITETPPEGLAAEHVDAPAGAGEHLVADALTGLAAHRRASAIVVGSRGQSAMCQVLLGSVARATLRAAHRPVLVVPGP
>NZ_AP022605.1|WP_085192424.1|618384_619590_+|NAD(P)/FAD-dependent-oxidoreductase
MYNHQVSTSGGIVIVGGGLAAARTAEQLRRSNYPGPVTIVSEEDHLPYDRPPLSKEVLRSETDDVTLKPAEFYREKDITVLLGTGAATVDTAGRKITLTDGREIGYDELVIATGLVPKRIPSFPDLTGIHVLRNFDQSLKLRQEAGSARRAVVIGAGFIGCEVAASLRKLGVEVVLVEPQPAPLASVLGRQIGGLVARLHRAEGVDVRCGVGVAEVKGQDVDGQQKVRSVVLSDGTEVQADIVVVGIGSRPATDWLEGSGIALDNGVVCDAEGRSSAPHVWAIGDVASWRDTVGNQVRVEHWSNVADQARVLVPAMLGQGVPGVVSVPYFWSDQYDVKIQCLGKPEADDTVHIVEDDGRKFLAYYERDGVVAGVVGGGMPAKVMKTRSKIANSAPIAEVLG
>NZ_AP022605.1|WP_085192423.1|619619_620891_-|VOC-family-protein
MNDHTDPLWVLHGDDLPVPPDPAFAARLRARLQSALRLPDHTEPDHTEGVEMSRTDTALAAVVARPAALPYLAVADARAAIDWYVDALGATPAGEPMMMDDGRIGHAELTLSGGVLYLADEFPELGLKAPAPEHVSVSLLLQVADTDAALRRAHDHGAHVQREPYDAHGSRTAAIIDPFGHRWMLSGPVTGAGTPIRHGDVGYVSLWTRDTERAAAFYGHVLGWTYDAATHEVTNTALPTGIFAGDGPATLFCCYAVDDLDRARQSIVAAGGTLGETTGHDFGTTQDATDPLGNRFAVFTPSRPTPRPALNGTGPGALSYITYEVGDSALFREFYGRVLSWTFDPGRIADGWQVNESHPMAGVAGGSARSATVPMWTVADVDDAVRRVREAGGSVLQQPHRQPYGLMAECVDDQGARFYLGQF
>NZ_AP022605.1|WP_085192422.1|620887_621412_-|sigma-70-family-RNA-polymerase-sigma-factor
MGVSAEPDGEDASRALLALYDDALPTVYGYFVRRCPDRGTAEDLTSETFLAAMDAARRGASVPISVPWLIGVARHKLADHYRRGSHRHAVAVADLPEPGEPVDGWDAELDRIVAESVLAQLPEHHRTVLALRYLDGCSVPECAELIGRTVHATEALLTRARRAFRSHYPEGGRP
>NZ_AP022605.1|WP_085192421.1|621451_622051_-|mycofactocin-system-transcriptional-regulator
MRQDSAPRVGRRRSTTRDHITDVALELFAARGFDEVSVDDVAAAAGIARRTLFRYYSSKSAIPWGHFDAHLDHMRHLFDDLDPTVPVDEALRGALLAFNHFGPEETTRHRQRMRVILETDALQAYSMTMYAGWRAVIAQFVAARTGVKAQDLVPQTVAWTMLGVALSAYEQWLADEAVSLAQALGDAFDTVRDGLRAVH
>NZ_AP022605.1|WP_085192420.1|622143_622302_+|mycofactocin-precursor
MEPNQHVIEGAAGAAQAATSDAATSDAATSENELVTETLVEEVSIDGMCGVY
>NZ_AP022605.1|WP_085192419.1|622304_622598_+|mycofactocin-biosynthesis-chaperone-MftB
MAAPVAFDPDLRWRLHHQVAVRPEPFGALLYHFGTRKLSFLKNTTIVDVVNSLADHRDARSACRAAGIDDRQQAPYLHALGVLVQSKMLVCEEEPAS
>NZ_AP022605.1|WP_085192418.1|622594_623800_+|mycofactocin-radical-SAM-maturase
MTSVVPAPAPGGAPVPRLVEQFEHGLDAPICLTWELTYACNLACVHCLSSSGKRDPRELSTQQCKDIIDELERMQVFYVNIGGGEPTVRPDFWELVDYATAHHVGVKFSTNGVRITGEVAAKLAASDYVDVQISLDGATAEINDAVRGPGSFAMAERALENLAAAGFTDAKISVVVTRHNVGQLDDFAALASRYGATLRITRLRPSGRGADVWDDLHPTAEQQVELYDWLVAKGERVLTGDSFFHLSGLGEPGALAGLNLCGAGRVVCLIDPVGDVYACPFAIHDKFLAGNILSDNGFKSVWQNSALFRELREPQSAGACSGCGHYDACRGGCMAAKFFTGLPLDGPDPECVQGYGAPALELDRVKPKPSGDHSRGTGQQGPIPLKLLTKPPARLCDESPV
>NZ_AP022605.1|WP_085192417.1|623802_624996_+|mycofactocin-biosynthesis-FMN-dependent-deaminase-MftD
MARDKWFETVAIAQQRAKKRLPKSVYSSLISASEKGLTVSDNVESFSELGFAPHVVGAPEKRDLSTTVMGQELSMPVMISPTGVQAVDPDGEVAVARAAAARGTAMGLSSFASKPIEEVVAANPKVFFQIYWLGGRETILERVQRAKEAGAVGLIVTTDWSFSHGRDWGSPKIPEQMNLRTMFRMSPEVITKPRWLWGFGKTLSPPDLRVPNQARRGEPGPAFFQVYGEWMNTPPPTWEDIAWLRERWDGPFMLKGIVRVDDARRAVDAGVSAISVSNHGGNNLDGTPATIRCLPAVADAVGDQVEVLLDGGIRRGSDVVKALALGARAVMIGRAYLWGLAANGQAGVENVLDILRGGIDSALMGLGRASIHDLGPDDILVPDGFTRALGVPTADQT

Crispr_ID: NZ_AP022605_3

• CRISPR_ID: NZ_AP022605_3
• CRISPR_location: 2858247-2858339
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_AP022605_3

Consensus_repeat	Method
TATCCGCCTCCGCCGCCCGGATAT	CRISPRCasFinder

spacers of NZ_AP022605_3

>3.1|2858271|45|NZ_AP022605|CRISPRCasFinder
CAGTCCTACGGCTCGTACGGCACTCCGTACGACACACCCGCCGGG

CRISPR arrays and Neighbor proteins around NZ_AP022605_3

CRISPR arrays

The CRISPR arrays of NZ_AP022605_3

>merge|NZ_AP022605|3|2858247-2858339|CRISPRCasFinder
TATCCGCCTCCGCCGCCCGGATATCAGTCCTACGGCTCGTACGGCACTCCGTACGACACACCCGCCGGGTATCCGCCACCGCCGCCCGGATAT

>NZ_AP022605|3|2|2858247-2858339|CRISPRCasFinder
TATCCGCCTCCGCCGCCCGGATAT	CAGTCCTACGGCTCGTACGGCACTCCGTACGACACACCCGCCGGG
TATCCGCCACCGCCGCCCGGATAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP022605.1|WP_085189223.1|2852828_2854046_-|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC	unknown	unknown	gnl|CDD|236947
NZ_AP022605.1|WP_085189216.1|2849942_2850773_-|hypothetical-protein	unknown	unknown	gnl|CDD|270324
NZ_AP022605.1|WP_085189221.1|2852238_2852832_-|suppressor-of-fused-domain-protein	unknown	unknown	gnl|CDD|377450
NZ_AP022605.1|WP_085189214.1|2849104_2849941_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|212491
NZ_AP022605.1|WP_085189241.1|2864125_2864542_-|Sec-independent-protein-translocase-subunit-TatB	unknown	unknown	gnl|CDD|179538
NZ_AP022605.1|WP_085189233.1|2858654_2859638_-|CoA-ester-lyase	unknown	unknown	gnl|CDD|225184
NZ_AP022605.1|WP_085189323.1|2855882_2857280_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270453
NZ_AP022605.1|WP_085189247.1|2866591_2867374_-|RNA-polymerase-sigma-factor-SigE	unknown	unknown	gnl|CDD|236606
NZ_AP022605.1|WP_085189239.1|2861596_2862919_+|lytic-murein-transglycosylase	unknown	unknown	gnl|CDD|225501
NZ_AP022605.1|WP_163784011.1|2850786_2850987_-|hypothetical-protein	unknown	unknown	unknown
NZ_AP022605.1|WP_085189243.1|2864541_2866032_-|trypsin-like-peptidase-domain-containing-protein	unknown	unknown	gnl|CDD|273938
NZ_AP022605.1|WP_085189237.1|2860955_2861471_+|DUF1003-domain-containing-protein	unknown	unknown	gnl|CDD|377629
NZ_AP022605.1|WP_085189229.1|2857458_2857998_-|DUF4199-domain-containing-protein	unknown	unknown	gnl|CDD|236512
NZ_AP022605.1|WP_085189227.1|2854947_2855886_-|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|224096
NZ_AP022605.1|WP_085189249.1|2867552_2868215_+|O-methyltransferase	unknown	unknown	gnl|CDD|226607
NZ_AP022605.1|WP_085189225.1|2854050_2854887_-|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl|CDD|223472
NZ_AP022605.1|WP_085189245.1|2866103_2866502_-|RNA-polymerase-subunit-sigma-70	unknown	unknown	unknown
NZ_AP022605.1|WP_085189325.1|2862975_2864121_+|Mrp/NBP35-family-ATP-binding-protein	unknown	unknown	gnl|CDD|378455
NZ_AP022605.1|WP_085189235.1|2859663_2860959_+|magnesium-transporter	unknown	unknown	gnl|CDD|225148
NZ_AP022605.1|WP_085189219.1|2851127_2852237_+|magnesium/cobalt-transporter-CorA	unknown	unknown	gnl|CDD|213364

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP022605.1|WP_085189223.1|2852828_2854046_-|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC	gnl|CDD|236947	PRK11650, ugpC, sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC.	0
NZ_AP022605.1|WP_085189216.1|2849942_2850773_-|hypothetical-protein	gnl|CDD|270324	cd13606, PBP2_ProX_like, Bacterial substrate-binding protein ProX of ABC-type osmoregulated transporter and its related proteins; the type 2 periplasmic-binding protein fold. This group includes periplasmic substrate-binding component of ABC transport systems from gram-negative and -positive bacteria that are involved in uptake of osmoprotectants (also termed compatible solutes) such as betaine, choline, proline betaine, carnitine, and L-proline. To counteract the efflux of water, many microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	2.81018e-47
NZ_AP022605.1|WP_085189221.1|2852238_2852832_-|suppressor-of-fused-domain-protein	gnl|CDD|377450	pfam05076, SUFU, Suppressor of fused protein (SUFU). SUFU, encoding the human orthologue of Drosophila suppressor of fused, appears to have a conserved role in the repression of Hedgehog signaling. SUFU exerts its repressor role by physically interacting with GLI proteins in both the cytoplasm and the nucleus. SUFU has been found to be a tumor-suppressor gene that predisposes individuals to medulloblastoma by modulating the SHH signaling pathway. Genomic contextual analysis of bacterial SUFU versions revealed that they are immunity proteins against diverse nuclease toxins in polymorphic toxin systems.	1.85794e-27
NZ_AP022605.1|WP_085189214.1|2849104_2849941_+|SDR-family-oxidoreductase	gnl|CDD|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	2.64122e-56
NZ_AP022605.1|WP_085189241.1|2864125_2864542_-|Sec-independent-protein-translocase-subunit-TatB	gnl|CDD|179538	PRK03100, PRK03100, Sec-independent protein translocase subunit TatB.	1.40527e-74
NZ_AP022605.1|WP_085189233.1|2858654_2859638_-|CoA-ester-lyase	gnl|CDD|225184	COG2301, CitE, Citrate lyase beta subunit [Carbohydrate transport and metabolism].	1.9948e-65
NZ_AP022605.1|WP_085189323.1|2855882_2857280_-|ABC-transporter-substrate-binding-protein	gnl|CDD|270453	cd14750, PBP2_TMBP, The periplasmic-binding component of ABC transport systems specific for trehalose/maltose; possesses type 2 periplasmic binding fold. This group represents the periplasmic trehalose/maltose-binding component of an ABC transport system and related proteins from archaea and bacteria. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.94805e-101
NZ_AP022605.1|WP_085189247.1|2866591_2867374_-|RNA-polymerase-sigma-factor-SigE	gnl|CDD|236606	PRK09647, PRK09647, RNA polymerase sigma factor SigE; Reviewed.	1.14724e-135
NZ_AP022605.1|WP_085189239.1|2861596_2862919_+|lytic-murein-transglycosylase	gnl|CDD|225501	COG2951, MltB, Membrane-bound lytic murein transglycosylase B [Cell envelope biogenesis, outer membrane].	1.12224e-34
NZ_AP022605.1|WP_085189243.1|2864541_2866032_-|trypsin-like-peptidase-domain-containing-protein	gnl|CDD|273938	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family. This family consists of a set proteins various designated DegP, heat shock protein HtrA, and protease DO. The ortholog in Pseudomonas aeruginosa is designated MucD and is found in an operon that controls mucoid phenotype. This family also includes the DegQ (HhoA) paralog in E. coli which can rescue a DegP mutant, but not the smaller DegS paralog, which cannot. Members of this family are located in the periplasm and have separable functions as both protease and chaperone. Members have a trypsin domain and two copies of a PDZ domain. This protein protects bacteria from thermal and other stresses and may be important for the survival of bacterial pathogens.// The chaperone function is dominant at low temperatures, whereas the proteolytic activity is turned on at elevated temperatures. [Protein fate, Protein folding and stabilization, Protein fate, Degradation of proteins, peptides, and glycopeptides].	1.3598e-90
NZ_AP022605.1|WP_085189237.1|2860955_2861471_+|DUF1003-domain-containing-protein	gnl|CDD|377629	pfam06210, DUF1003, Protein of unknown function (DUF1003). This family consists of several hypothetical bacterial proteins of unknown function.	9.13342e-44
NZ_AP022605.1|WP_085189229.1|2857458_2857998_-|DUF4199-domain-containing-protein	gnl|CDD|236512	PRK09430, djlA, co-chaperone DjlA.	0.00568216
NZ_AP022605.1|WP_085189227.1|2854947_2855886_-|sugar-ABC-transporter-permease	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	7.13588e-78
NZ_AP022605.1|WP_085189249.1|2867552_2868215_+|O-methyltransferase	gnl|CDD|226607	COG4122, COG4122, Predicted O-methyltransferase [General function prediction only].	2.22595e-60
NZ_AP022605.1|WP_085189225.1|2854050_2854887_-|carbohydrate-ABC-transporter-permease	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	3.49249e-76
NZ_AP022605.1|WP_085189325.1|2862975_2864121_+|Mrp/NBP35-family-ATP-binding-protein	gnl|CDD|378455	pfam10609, ParA, NUBPL iron-transfer P-loop NTPase. This family contains ATPases involved in plasmid partitioning. It also contains the cytosolic Fe-S cluster assembling factor NBP35 which is required for biogenesis and export of both ribosomal subunits.	1.49495e-122
NZ_AP022605.1|WP_085189235.1|2859663_2860959_+|magnesium-transporter	gnl|CDD|225148	COG2239, MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism].	1.94041e-58
NZ_AP022605.1|WP_085189219.1|2851127_2852237_+|magnesium/cobalt-transporter-CorA	gnl|CDD|213364	cd12830, MtCorA-like, Mycobacterium tuberculosis CorA-like subfamily. This bacterial subfamily belongs to the Thermotoga maritima CorA (TmCorA)-like family of the MIT superfamily of essential membrane proteins involved in transporting divalent cations (uptake or efflux) across membranes. This subfamily includes the Mg2+ transporter Mycobacterium tuberculosis CorA (which also transports Co2+). Thermotoga maritima CorA forms funnel-shaped homopentamers, the tip of the funnel is formed from two C-terminal transmembrane (TM) helices from each monomer, and the large opening of the funnel from the N-terminal cytoplasmic domains. The GMN signature motif of the MIT superfamily occurs just after TM1, mutation within this motif is known to abolish Mg2+ transport by a related protein, Saccharomyces cerevisiae Alr1p. Natural variants in this signature sequence may be associated with the transport of different divalent cations. The functional diversity of the MIT superfamily may also be due to minor structural differences regulating gating, substrate selection, and transport.	1.29478e-165

Protein sequences

>NZ_AP022605.1|WP_085189229.1|2857458_2857998_-|DUF4199-domain-containing-protein
MTSPFQSGPTSGAQPTSLPTSPAGAPGVPAALPTPPKGWPIGSYPTYAEAQRAVDFLSDQQFPVQQVTIVGVDLMQVERVTGRLSWPKVLGGGVLTGAWLGLFIGLILGFFSPNPWSALLTGLIAGVFFGLITSAIPYAMARGTRDFSSTMQLVAGRYDVLCDPKNAEQGRDLLARLTI
>NZ_AP022605.1|WP_085189323.1|2855882_2857280_-|ABC-transporter-substrate-binding-protein
MRARRLGAAAVAALATASTVSACGSGGDGNVVNLYTSANELATFTELAERCTEELDNGFTVRQVSLPKSADEQRLQLARRLTGNDKTLDLMAMDVVWTAEFAEAGWIVPLSEDPAGLAEPDATTDTLPGPLETATWQDKLYASPITTNTQVLWYRADLIPEPPGTWDAMVAEAARLYEAGQPSWIAVQGKQYEGLVVWFNTLLESAGGQVLSDDGTKVTLTDTPEHRAATVKALQTIKAVATAPGADPSITQTDESTARLALEQGNAALEVNWPFVLPSMLENAVKGGVGFLPLDERPDLTSAINEAGTFSPSDEQFRTAYDASRQVFGFAPFPEVNPGTPAKVTLGGLNLAVAKTSQHKAAAFEVMRCLRSPENQRTTSVEGGLPAVRASLYDDPAFQARYPQYDIIRRQLIDAAVRPATPQYQAVSTRISVTLAPIDQIDPERTADELAEQVQKAIDGKGLIP
>NZ_AP022605.1|WP_085189227.1|2854947_2855886_-|sugar-ABC-transporter-permease
MTATVDAAPATAAPTATSGGSDDARSERRLAFLLISPAVILMLAVTGYPIVYSVWLSLQRYNLATPDDTEFVGLQNYVTVLTDGYWWSALAVTLGITIVSVAIEFVLGMTLALVMHRTIFGKGVVRTAILIPYGIVTVAASYSWYYAWTPGTGYLANLLPEGSAPLTEQLPSLAIVVLAEVWKTTPFMALLLLAGLALVPQELLNAAQMDGAGAWKRLVKIILPLIKPAILVALLFRTLDAFRVFDNIYVLTQGANNTGSVSILGYDNLFKAFSLGLGSAISVLIFLCVAIIAFVYIKLFGASAPGSQEDGR
>NZ_AP022605.1|WP_085189225.1|2854050_2854887_-|carbohydrate-ABC-transporter-permease
MNQRVTAGRGTGWAVVNVLVVLYALVPVLWILSLSLKPTSSVKDGKLIPTEITFANYKGIFNGDAFSSALVNSIGIGLVTTVIAVVFGGMAAYAVARLTFPGKKLLVGVALLIAMFPQISLVTPLFNIERSLGLFDTWPGLIIPYITFALPLAIYTLSAFFREIPWDLEKAAKMDGATPAQAFRKVIAPLAAPGIVTAAILVFIFAWNDLLLALSLTATQRAITAPVAIANFTGSSQFEEPTGSIAAGAMVITIPIIVFVLIFQRRIVAGLTSGAVKG
>NZ_AP022605.1|WP_085189223.1|2852828_2854046_-|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC
MAEIVLDKVTKSYPNGATAVKDLSITIADGEFVILVGPSGCGKSTTLNMIAGLEDISSGELRIGGERVNEKAPKDRDIAMVFQSYALYPHMSVRQNIAFPLTLAKVKKEQINAKVEETAKILDLTELLDRKPSQLSGGQRQRVAMGRAIVRNPKAFLMDEPLSNLDAKLRVQMRTEISRLQNRLGTTTVYVTHDQIEAMTLGDRVVVMLSGVVQQIGSPEELYNAPANLFVAGFIGSPAMNFFPGSLTDVGVRLPFGEVTLTREAHDLINRRGKTKNIIVGVRPEHLEDASVLDGYARIRALSFEVIADMVESLGAEKYVHFRIEGAGAQSAQLEQLAVESGQGENEFVARVSTESQVRQGGTIQLALDTSKLVIFDGDSGENLTIPDKRSAEPPRVAEPAKPAE
>NZ_AP022605.1|WP_085189221.1|2852238_2852832_-|suppressor-of-fused-domain-protein
MTDVLTAVRAHLGEHFRGVGITTEPAAASVTFLGTERIEVLRFGPGDDGVAHYVSLGCSRHPMFDPTELVTDAIHGPRAEVVLALRGPTPKGLVRSVAVLAAAPAVEGLVLEADALIDLETPLWDLSPFTAFLLGSSDIDDVPLPGPLPAVTVFSATPITPTEAAWVRLRGADAMREAWTADGVDVLDPARRAASPP
>NZ_AP022605.1|WP_085189219.1|2851127_2852237_+|magnesium/cobalt-transporter-CorA
MPSFRALPPSLLRQGGRQHQSTEPDASSIHVPVARATVDCAVYAGGTRLPGKYAHSAALEKVRELEHEGRPAFVWIGLHEPDEHQMQAVADVFDLHELAVEDAVHAHQRPKLERYDDTLFLVLKTITYVEHGEGPKAHEIVETGEIMVFVGADFVVTVRHGVHGGLAGVRRQIDTSPARCTLGPHAVMHAIADHVVDTYLEVTDLVANDIDALEENVFSPSSATDIERIYLAKREVVEMRRAISPLNLALQRIGSDHNDLISKEVRRYFRDVLDHNTQAADRIASYDDVLSSLVQAAVGKVSMQQNIDMRKISAYVAIAAVPTAMAGIYGMNFDHMPELDWIYGYPAVLLFMASTCLLLYFTFRRNHWL
>NZ_AP022605.1|WP_163784011.1|2850786_2850987_-|hypothetical-protein
MSTSQVVIEDADPARTLGGLHTGCRPGRPCDPGRPRTEANSALFKTFGADLASAVAAAVDAASTAG
>NZ_AP022605.1|WP_085189216.1|2849942_2850773_-|hypothetical-protein
MRRLLFTLCTMLLTACGGPQTGPSLTIGSAEDEASVITAHLYAAALRHYGTGTRVEPTADPLTALDAGDVAVVPGLTGRLLDRFQPDATARADEQVYRDMVSALPEGVAAGDYTTAAEDKPALAVTVSTVAELGGQDLSAVARRCGDLRLGQVRGARTPATVGTCRLPVPREFRDAAGLFAAVKAGGVDAAWTTTAMPDIPSDLVVLTDGTSLVRAENVVPLYRRNGLAESQVLALNEVAGVLDTAALAEMRARVREGADPAVVADEWLAEHPLRD
>NZ_AP022605.1|WP_085189214.1|2849104_2849941_+|SDR-family-oxidoreductase
MQGFAGKVAVVTGAGSGIGQALAIELARSGASVAISDVNLEGLAVTEERIKESGTGAPVKVNRLDVTEREAFLLYADEVKQHFGKVNQIYNNAGIAFMGDIEVSQFKDIERVMDVDFWGVVNGTKAFLPHLIASGDGHVINVSSVFGLFSVPSQGAYNAAKFAVRGFTEALNQEMAVAGHPVKVTTVHPGGIKTAIARNATAVEGLDADELATFFDKRLANTTPEKAAQVILDGVRKNKARVLIGTDAKALDVIIRILGPRYQRLFPSVTSRFMPGPH
>NZ_AP022605.1|WP_085189233.1|2858654_2859638_-|CoA-ester-lyase
MNHAIPPREPGDSARPRRTCLSVPGSSAKMIEKAKRLPADEVFLDLEDAVAPEAKAEARTRVAMALGESGWGGQLRGVRVNDWTTPWTYADVIEVVSTAGAELDLIVLPKVTDVSHVHALDLLLTQLETTHGLPVGRIGIEAQIENAAGLTHIDAIAAGPRMQALVLGPADLMASLNMRTLVVGEQPEGYDVGDAYHHVFMRLLIAARTHGIHAIDGPFLKVRDVEAFRRVARRSAALGFDGKWVLHPDQITAGNEIFNPRQQDYDHAELILEAYHWHTSQAGGARGAVMLGDEMIDEASRKMALVVAAKGRAAGMTRQAEPFRPPA
>NZ_AP022605.1|WP_085189235.1|2859663_2860959_+|magnesium-transporter
MASVNRVYAARLAGMVVLGPDGESIGRVRDIVISISIVRQQPRVLGLVVELLSRRRIFVPILRVTAIEPSAVTLTTANVSLRKFVQRPGEVLVVGQVLDTRVRVDDPDLSQLAGIDVVVVDLGIEQSRTRDWLVTRVAVRTQRRLGRRSNIHVVEWAHVHGLTPSGLAMPDQGVASLLEQFEGQRAVEVAEAIRELPAKRRYEVVNALDDERLADVLQELPVDDQADVLRQMKTDRAADVLEAMDPDDAADLLGSMTPADAETLLRRMDPEDSQDVRRLLSHSPDTAGGLMTSEPVVLAPDVTVAEALARVRDPDLTPALASLVFVARPPTATPTGQYLGCVHLQRLLREPPATLVSGILDTDLPSLTPQDSLGAVTRYFAAYNLVCGPVVDEQNHLLGAVSVDDVLDHLLPDDWRERVTEPELTGTEGTV
>NZ_AP022605.1|WP_085189237.1|2860955_2861471_+|DUF1003-domain-containing-protein
MSDLSARGRLDTPRTPRRISFNVDREAAGQFGERVARFLGTGRYLAVQTMIVIVWIALNLFAVSLRWDPYPFILLNLAFSTQAAYAAPLILLAQNRQENRDRVSLEEDRRRAAQTKADTEYLARELAALRLAVGEVATRDYLRRELEELREMVATLLAANDGDDRRSKRTG
>NZ_AP022605.1|WP_085189239.1|2861596_2862919_+|lytic-murein-transglycosylase
MVAARRRAGKVLGKPAAGVVIIAPLVLAGAVGASAPTLQHSVSNAAVTPLAAVASGQRNSTGPSVVAVKKAPSAFRIAASTVSSPPPAVVVNSPGSMKIPAMALSAYRNAERMMAAAVPNCGVSWNLLAGIGRIESGHAYGGATDSRGTAVSPIYGPALDGTLPGNEVIELSRNANRVTYARAMGPMQFLPGTWARYASDGDGDGKADVQNLYDSALAAARYLCSGGLNLRDPSQVMSAILRYNNSVAYARNVLGWAGGYATGVVPVDLPPINGPVPALGESHVDRSDGLGPGTPLNAMGLPADDPLALVPLLTRTDASRMPGTNVPGFAPGQRLGPLPGPAPKAPATTAPAPAALAPWVPPWMAPPPPPPPSCVVFCLDDTPAPAALPAPGPVPPAASPTLPGPPAARAPGPVLAPAPPAPAAPLPAPAPIGPAPGPVV
>NZ_AP022605.1|WP_085189325.1|2862975_2864121_+|Mrp/NBP35-family-ATP-binding-protein
MSQTPDGRQTAIRAALAKVIDPELRRPITDLGMVKNVTVDSGDGSVHVEVYLTTAACPKRNEITEQVQRAVADVPGTGAVRVSLDVMNDEQRAELRKQLRGDSREPVIPFAQPGSLTRVYAVASGKGGVGKSSVTVNIATAMAARGLSVGVLDADIYGHSVPRMMGTTDRPTQVDSMILPPIAHEVKVISIAMFTQGNTPVVWRGPMLHRALQQFLADVFWGDLDVLLLDLPPGTGDVAISVAQLIPGAEILVVTTPQLAAAEVAERAGAIALQTRQRVVGVVENMSGLLMPDGSTMPLFGEGGGRQVAERLSRAVGADVPLLGQVPLDPALVSAGDSGVPLVLSAPDSPAGKELRGVADALSARKRGLAGMSLGLDPAGR
>NZ_AP022605.1|WP_085189241.1|2864125_2864542_-|Sec-independent-protein-translocase-subunit-TatB
MFSNIGWGEMLILVIAGLVILGPERLPGAIRWTSDAVRQARDYVSGATTQLRQDFGAEFEDLREPITELQKLRRMTPRAALTKHLLDGDDSFFTGKFEQQNGNPTTGQEKPATPVTPPAAAADPPRESTATPYDSDAT
>NZ_AP022605.1|WP_085189243.1|2864541_2866032_-|trypsin-like-peptidase-domain-containing-protein
MTNQDQASRRMAPRPVERPPVDPAAQRAFARPSGVSGSFLGVDPHRHQAEYTPKDPAPDPVLAEAFGRPPNASDSLQRHPADAGALDAERSGDTADTEPDPWRDPNAPVALGTPAVHAPAPVQPPAHVGRLGVRDVLFGRKVSYVGLAILLLTALMVGALGGWVGNKTAETVQAFTTSKVTLETSDSGDPPEGRITKVADAVADSVVTIEAKSGQEGSQGSGVVIDGRGYIVTNNHVISEAATNPAAFEMTVVFNDGKEVPANLVGRDPKTDLAVLKVDNVDNLTVAKMGDSDTLQVGEEVIAAGAPLGLRSTVTAGIISALNRPVPLSGDGSDTDTVIDGVQTDASINHGNSGGPLIDMDANVIGINTAGKSLSESASGLGFAIPVNEVKTVVEALIRDGRISHPTLGLTAKSVSNDVASGAQVANVMAGSAAERAGILENDVVVKVGTRDVADADEFVVAVRQLKIGEPAPIEVVRDGRPVTLTVTPTPDASTD
>NZ_AP022605.1|WP_085189245.1|2866103_2866502_-|RNA-polymerase-subunit-sigma-70
MVDPGHMFRRAFSWLPAQFASQSKAPVGAPRQFGSTEHLSIEAVAAFVDGELSMTAHMRAANHLSLCAQCAAEVDAQGQARTALRDSQPIAIPNTLLGMLSQIPQHMPHSPVEGAEQPKFADDRARDRRKRR
>NZ_AP022605.1|WP_085189247.1|2866591_2867374_-|RNA-polymerase-sigma-factor-SigE
MEHGRRLRFGNRHAADRVAHDDQPTTMTDAGHDSAGLDLEDLTTTTTAAAQAAPVSMAHLEQFSDSDWVEPTDELTGTAVYDATGDKTTMPSWDELVRQHADRVYRLAYRLSGNQHDAEDLTQETFIRVFRSVQNYQPGTFEGWLHRITTNLFLDMVRRRGRIRMEALPEDYDRVPADDPNPEQIYHDSRLGPDLQAALDSLPPEFRAAVVLCDVEGLSYEEIGATLGVKLGTVRSRIHRGRQALRDYLARHAPGAAASA
>NZ_AP022605.1|WP_085189249.1|2867552_2868215_+|O-methyltransferase
MASTDDPAGQRPSRAEAIVTHAEQSISEDAIVAAARERAVDIGAGAITPAVGALLSVMARLTEAKAVVEVGTGAGVSGLWLLSGMREDGVLTTIDVEPEHQRIAKQAFIEAGIGPGRTRLISGRAQDVLTRLADDSYDLVFIDGDPIDQPQFVVEGVRLLRSGGAIVVHRAALGGRAGDAAANDPEVIAVREAARLIAEDERLTPVLVPLGDGLLAAARD

Crispr_ID: NZ_AP022605_4

• CRISPR_ID: NZ_AP022605_4
• CRISPR_location: 3738444-3738547
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_AP022605_4

Consensus_repeat	Method
GAAGGCCACGACGGCGGAGCCGACGGCACCGC	CRISPRCasFinder

spacers of NZ_AP022605_4

>4.1|3738476|40|NZ_AP022605|CRISPRCasFinder
AGACGCGGGCGAAGGAACCGCCGACGGCGGCTCGAACCCG

CRISPR arrays and Neighbor proteins around NZ_AP022605_4

CRISPR arrays

The CRISPR arrays of NZ_AP022605_4

>merge|NZ_AP022605|4|3738444-3738547|CRISPRCasFinder
GAAGGCCACGACGGCGGAGCCGACGGCACCGCAGACGCGGGCGAAGGAACCGCCGACGGCGGCTCGAACCCGGAAGGTCACGACGGCGGAGCCGACGGCACCGC

>NZ_AP022605|4|3|3738444-3738547|CRISPRCasFinder
GAAGGCCACGACGGCGGAGCCGACGGCACCGC	AGACGCGGGCGAAGGAACCGCCGACGGCGGCTCGAACCCG
GAAGGTCACGACGGCGGAGCCGACGGCACCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP022605.1|WP_085192251.1|3732811_3733762_+|polysulfide-reductase-NrfD	unknown	unknown	gnl|CDD|225838
NZ_AP022605.1|WP_163784264.1|3738057_3738222_+|hypothetical-protein	unknown	unknown	unknown
NZ_AP022605.1|WP_085192302.1|3748192_3749251_-|glycoside-hydrolase	unknown	unknown	gnl|CDD|235334
NZ_AP022605.1|WP_099050281.1|3741680_3742340_+|thiocyanate-hydrolase-subunit-gamma	unknown	unknown	gnl|CDD|188402
NZ_AP022605.1|WP_133055566.1|3745333_3745690_-|hypothetical-protein	unknown	unknown	unknown
NZ_AP022605.1|WP_085192253.1|3734562_3735135_-|hypothetical-protein	unknown	unknown	unknown
NZ_AP022605.1|WP_085192250.1|3731915_3732812_+|4Fe-4S-dicluster-domain-containing-protein	unknown	unknown	gnl|CDD|319882
NZ_AP022605.1|WP_085192254.1|3735225_3735933_+|TVP38/TMEM64-family-protein	unknown	unknown	gnl|CDD|223475
NZ_AP022605.1|WP_085192264.1|3746351_3746738_+|DUF2267-domain-containing-protein	unknown	unknown	gnl|CDD|378360
NZ_AP022605.1|WP_099050278.1|3729309_3731919_+|molybdopterin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|273689
NZ_AP022605.1|WP_085192301.1|3728652_3729222_+|dehydrogenase	unknown	unknown	gnl|CDD|239153
NZ_AP022605.1|WP_085192248.1|3726793_3728491_+|SelB-C-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|225815
NZ_AP022605.1|WP_085192252.1|3733766_3734477_-|cutinase-family-protein	unknown	unknown	gnl|CDD|366455
NZ_AP022605.1|WP_085192266.1|3747251_3748157_+|serine-hydrolase	unknown	unknown	gnl|CDD|379138
NZ_AP022605.1|WP_085192257.1|3738560_3739775_+|cupin-like-domain-containing-protein	unknown	unknown	gnl|CDD|369647
NZ_AP022605.1|WP_085192259.1|3740766_3741606_+|nitrile-hydratase-subunit-beta	unknown	unknown	gnl|CDD|376740
NZ_AP022605.1|WP_085192262.1|3742740_3745311_+|DEAD/DEAH-box-helicase	unknown	unknown	gnl|CDD|378795
NZ_AP022605.1|WP_085192261.1|3742350_3742704_+|thiocyanate-hydrolase	unknown	unknown	unknown
NZ_AP022605.1|WP_085192255.1|3736275_3737910_+|fatty-acyl-AMP-ligase	unknown	unknown	gnl|CDD|236091
NZ_AP022605.1|WP_085192258.1|3739771_3740659_+|sucrase-ferredoxin	unknown	unknown	gnl|CDD|227101

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP022605.1|WP_085192251.1|3732811_3733762_+|polysulfide-reductase-NrfD	gnl|CDD|225838	COG3301, NrfD, Formate-dependent nitrite reductase, membrane component [Inorganic ion transport and metabolism].	7.43532e-13
NZ_AP022605.1|WP_085192302.1|3748192_3749251_-|glycoside-hydrolase	gnl|CDD|235334	PRK05035, PRK05035, electron transport complex protein RnfC; Provisional.	0.00312195
NZ_AP022605.1|WP_099050281.1|3741680_3742340_+|thiocyanate-hydrolase-subunit-gamma	gnl|CDD|188402	TIGR03887, Thiocyanate_hydrolase_subunit_gamma, thiocyanate hydrolase, gamma subunit. Members of this family are the gamma subunit of thiocyanate hydrolase. This family is closely related to the nitrile hydratase, alpha subunit (TIGR01323).	1.89573e-133
NZ_AP022605.1|WP_085192250.1|3731915_3732812_+|4Fe-4S-dicluster-domain-containing-protein	gnl|CDD|319882	cd10560, FDH-O_like, beta subunit of formate dehydrogenase O (FDH-O) and similar proteins. This subfamily includes beta subunit of formate dehydrogenase family O (FDH-O), which is highly homologous to formate dehydrogenase N (FDH-N), a member of the DMSO reductase family. In E. coli three formate dehydrogenases are synthesized that are capable of oxidizing formate; Fdh-H, couples formate disproportionation to hydrogen and CO2, and is part of the cytoplasmically oriented formate hydrogenlyase complex, while FDH-N and FDH-O indicate their respective induction after growth with nitrate and oxygen. Little is known about FDH-O, although it shows formate oxidase activity during aerobic growth and is also synthesized during nitrate respiration, similar to FDH-N.	6.64373e-143
NZ_AP022605.1|WP_085192254.1|3735225_3735933_+|TVP38/TMEM64-family-protein	gnl|CDD|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	1.43416e-32
NZ_AP022605.1|WP_085192264.1|3746351_3746738_+|DUF2267-domain-containing-protein	gnl|CDD|378360	pfam10025, DUF2267, Uncharacterized conserved protein (DUF2267). This domain, found in various hypothetical bacterial proteins, has no known function.	3.85772e-28
NZ_AP022605.1|WP_099050278.1|3729309_3731919_+|molybdopterin-dependent-oxidoreductase	gnl|CDD|273689	TIGR01553, Formate_dehydrogenase_major_subunit, formate dehydrogenase-N alpha subunit. This model describes a subset of formate dehydrogenase alpha chains found mainly in proteobacteria but also in Aquifex. The alpha chain contains domains for molybdopterin dinucleotide binding and molybdopterin oxidoreductase (pfam01568 and pfam00384, respectively). The holo-enzyme also contains beta and gamma subunits of 32 and 20 kDa. The enzyme catalyzes the oxidation of formate (produced from pyruvate during anaerobic growth) to carbon dioxide with the concomitant release of two electrons and two protons. The electrons are utilized mainly in the nitrate respiration by nitrate reductase. In E. coli and Salmonella, there are two forms of the formate dehydrogenase, one induced by nitrate which is strictly anaerobic (fdn), and one incuced during the transition from aerobic to anaerobic growth (fdo). This subunit is one of only three proteins in E. coli which contain selenocysteine. This model is well-defined, with a large, unpopulated trusted/noise gap. [Energy metabolism, Anaerobic, Energy metabolism, Electron transport].	0
NZ_AP022605.1|WP_085192301.1|3728652_3729222_+|dehydrogenase	gnl|CDD|239153	cd02752, MopB_Formate-Dh-Na-like, Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the major electron donor to the nitrate respiratory chain. Also included in this CD is the Desulfovibrio gigas tungsten formate dehydrogenase, DgW-FDH. In contrast to Fdh-N, which is a functional heterotrimer, DgW-FDH is a heterodimer. The DgW-FDH complex is composed of a large subunit carrying the W active site and one [4Fe-4S] center, and a small subunit that harbors a series of three [4Fe-4S] clusters as well as a putative vacant binding site for a fourth cluster. The smaller subunit is not included in this alignment. Members of the MopB_Formate-Dh-Na-like CD belong to the molybdopterin_binding (MopB) superfamily of proteins.	7.75417e-49
NZ_AP022605.1|WP_085192248.1|3726793_3728491_+|SelB-C-terminal-domain-containing-protein	gnl|CDD|225815	COG3276, SelB, Selenocysteine-specific translation elongation factor [Translation, ribosomal structure and biogenesis].	1.95223e-73
NZ_AP022605.1|WP_085192252.1|3733766_3734477_-|cutinase-family-protein	gnl|CDD|366455	pfam01083, Cutinase, Cutinase.	4.04566e-42
NZ_AP022605.1|WP_085192266.1|3747251_3748157_+|serine-hydrolase	gnl|CDD|379138	pfam13354, Beta-lactamase2, Beta-lactamase enzyme family. This family is closely related to Beta-lactamase, pfam00144, the serine beta-lactamase-like superfamily, which contains the distantly related pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	2.83531e-08
NZ_AP022605.1|WP_085192257.1|3738560_3739775_+|cupin-like-domain-containing-protein	gnl|CDD|369647	pfam08007, Cupin_4, Cupin superfamily protein. This family contains many hypothetical proteins that belong to the cupin superfamily.	4.58375e-33
NZ_AP022605.1|WP_085192259.1|3740766_3741606_+|nitrile-hydratase-subunit-beta	gnl|CDD|376740	pfam02211, NHase_beta, Nitrile hydratase beta subunit. Nitrile hydratases EC:4.2.1.84 are unusual metalloenzymes that catalyze the hydration of nitriles to their corresponding amides. They are used as biocatalysts in acrylamide production, one of the few commercial scale bioprocesses, as well as in environmental remediation for the removal of nitriles from waste streams. Nitrile hydratases are composed of two subunits, alpha and beta, and they contain one iron atom per alpha beta unit.	9.93235e-69
NZ_AP022605.1|WP_085192262.1|3742740_3745311_+|DEAD/DEAH-box-helicase	gnl|CDD|378795	pfam12029, DUF3516, Domain of unknown function (DUF3516). This presumed domain is functionally uncharacterized. This domain is found in bacteria. This domain is typically between 460 to 473 amino acids in length. This domain is found associated with pfam00270, pfam00271.	0
NZ_AP022605.1|WP_085192255.1|3736275_3737910_+|fatty-acyl-AMP-ligase	gnl|CDD|236091	PRK07768, PRK07768, long-chain-fatty-acid--CoA ligase; Validated.	0
NZ_AP022605.1|WP_085192258.1|3739771_3740659_+|sucrase-ferredoxin	gnl|CDD|227101	COG4759, COG4759, Uncharacterized protein conserved in bacteria containing thioredoxin-like domain [Posttranslational modification, protein turnover, chaperones].	2.63099e-25

Protein sequences

>NZ_AP022605.1|WP_163784264.1|3738057_3738222_+|hypothetical-protein
MSPPRSLARLVAASERAASRAADARWALARVRRDKAFTDRSRDNRLEHQRRVDK
>NZ_AP022605.1|WP_085192255.1|3736275_3737910_+|fatty-acyl-AMP-ligase
MSTFTETMYSNARSSVNGMVTGEPDLPVRHSWIEVHERARQVAGGLAAAGVGHGDAIAVLAGAPVEIAPTAQGIWMRGASLTMLHQPTPRTDLQRWAEETTAVIDMIDARAVIVSDPFMPAAPLLAGLGILVLTIADLLEHAPVEPVRTDDDDIALMQLTSGSTGSPKAVQITHANVVANAEAMIVGCDFDIDKDVIVSWLPCFHDMGMTGYLTVPMFFGAELVKVTPMDFLRDTLLWAKLIDKYGGTMTAAPNFAYNLLAKRLRRLASPGEFDLSSLRWALSGAEQVDPLDVEDLCEAGAPFGLNPDAIIPAYGMAETTVAVSFAECGGGMVVDEVDADLLAVLHRAVPANKGHTRRLVSLGRPLQGLEVRVLDEAGAVLAARGVGVIEVRGRPVTRGYTTTAGFVPAQDELGWYDTGDLGYLTEGGEIVVCGRLKDVIIMAGRNIYPTDIERAAARVTGVRPGCAVAIRLEGGHPRETFAVAVESKHVDDAEQVRRIQRQVAHEVVAEVDVRPRNVVVLEPGTIPKTPSGKLRRAHALSLID
>NZ_AP022605.1|WP_085192254.1|3735225_3735933_+|TVP38/TMEM64-family-protein
MTSRRRHIARLTLFAALVFGLFYLVTVERVIDVDTVRGAVAATGPVAPLTYVVVSATLGALFVPGPLLAGLSGLLFGPVLGTFVTLGATVGTAVVASLVGRRAGRDSARALLGPQRADLIDAQIERRGLWAVVGQRFIPGISDALASYALGAFGVPLWQMAVGAFIGSVPRAFVYTALGASIGDLSSPLAYTAIGIWVVTAVVGTFAAHRGYRRWRRRRPSVPTDDTPHPPVGRI
>NZ_AP022605.1|WP_085192253.1|3734562_3735135_-|hypothetical-protein
MCLGVDARLRRPGVVEWRVMPTPRLLIRWSVAAAAGTALLSFAALPAAARPASDAQGFIDSTARCASPSTAVAYGRTDSSRVAVCKSPDGKYQYRGVRVRDGAKLITAATATGDGEYVASNDVVTYTVTSEELIVAIGDDVLREETMLEFHGPGASTAPASPGAGPAPAKPTPTTPLPPPLPAEEGHRGA
>NZ_AP022605.1|WP_085192252.1|3733766_3734477_-|cutinase-family-protein
MSVVATWKAVRRLTGATGVGMALTSAAVSGGTVPVASAQPCPDIEVIFARGTAEPPGVGGTGQAFVDSLRSQIGWRTLGVYAVNYPASNDFASPDFPRTVVDGIRDASNRVQVMSVICPNTRLVLGGFSQGAMVSGFVTGDAVPQGVTPAPMPPALAPEVADNVAAVVLLGKPSGPFLQKYAMPPVVTGPLYATRTIELCAAGDPVCGPGGNTTAHGSYPFNGMVQQGAGFAATHL
>NZ_AP022605.1|WP_085192251.1|3732811_3733762_+|polysulfide-reductase-NrfD
MAREQLAVPKAEFRSYYGRQILKTPVWNWMIAAYFFAGGLSAGSAMLGAGADLTDRPGLRKVSRIGSLMSLLASMYFLIGDLGRPERFHHMLRVAKPSSPMSVGTWILGAYGPGAGVAAVAELMPARLRRTWAGRLLDRAARPAGLEAAAVAPGVASYTAVLLSHTAVPAWNLAYPYLPFVFTGSAAASGGGLGMLLAPLDESGPARRMAVAGAGLEVAASRTMERRLGIVGEAYTTGKAHRLRQWSEILTVGGAAGAVVGRNRAVIALSGAALLAGSALQRFGVLEAGVESTKDPKYVVVPQRERLAAGEPAGVG
>NZ_AP022605.1|WP_085192250.1|3731915_3732812_+|4Fe-4S-dicluster-domain-containing-protein
MNDNSFYGPLTDPAGEAGHSGHPERVGFFTDTSVCIGCKACEVACKEWNEVPDDGFNLLGMSFDNTGSLGANSWRHVAFIEQPASRTGSEPVDPGMPDVSGAGIDMVGQRPDFRWLMASDVCKHCTHAGCLDVCPTGALFRTEFSTVVVQQDICNGCGYCVSGCPYGVIERREGDGRAWKCTLCYDRLHDGLEPACAKACPTDSIQFGPLDELRERAAQRVEQLHQRGATEARLYGHDPNDGVGGDGAFFLLLDEPEVYGLPPDPVVPTRDAGAMWRYAGMAASALVGVAVSAFLGRS
>NZ_AP022605.1|WP_099050278.1|3729309_3731919_+|molybdopterin-dependent-oxidoreductase
MVIMGSNMAEAHPVGFQWVVEAKSRGTEVVHIDPRFTRTSALADRHVSLRAGSDIAFLGGVINHILSNELDFREYVTAYTNASFIVDEKFRGAEDLDGLFSGYDDETASYDPSTWQYETTDSEQGGAEAKEESAAYESGSGGPPVEGGAGPIPRDETLQHPRCVYQLLKRHYARYTPEMVERVCGVPAQQFLEVARKWTENSGRERTAALVYSVGWTQHTMGAQFIRAGAIIQLLLGNIGRPGGGVLALRGHASIQGSTDVPTLFNLLPGYLAMPKAGQETLADYIDDVKSRNQKGFWHNADAYMVSLLKEYWGQHATADNDFCFDYLPRINGDHGTYRTVMDMVDGKVFGYFLLGQNPAVGSAHGRLQRLGMANLDWLVVRDLVEIESATFWKSGPEIETGEITPETCRTEVFLFPAASHVEKAGTFTQTQRMLQWRDKAVEPPGDARSELWFFYHLGRILREKLAGSTDERDRPLLELSWDYAMEGDEPSGEDVLRRINGVDLTTGRAVDNYMSLKADGSTMCGCWIYSGVYADEVNQAARRKPHDQQGRYESEWGWTWPMNRRVLYNRASADPQGRPWSERKKLVWWDPDEGEWTGYDIPDFEKNKAPDYRPSPEAVGVEALHGDDPFIMQADGKGWLFAPNGVADGPLPTHYEPHESPVRNPLYAQQGNPARKVYGRADNPSNPSPPELHGDVFPFVFTAARLTEHHTAGGMSRQLPYLAELQPGLFVEVSPQLAAERGLSHMEWAHVITSRAAVDARVFVTDRMRPLRIDDHVVHQIWMPYHWGNAGLVDGDVVNDLLGVVVDPNVFIQESKVATCDIQPGRRPRGPALLEYVAMYRQRARITIDTGTDLDTTEPSTDHTEEPP
>NZ_AP022605.1|WP_085192301.1|3728652_3729222_+|dehydrogenase
MDLRKLIESWPVYRQLTGGDTLGRGTAAQSKRSLTLTPRTAEADHVAHSVCPFCAVGCAQQVYVKDDKVVQIEGNPDSPISRGRLCPKGSASKQLVTGPQRLTKIKYRPPYATEWQDLDLDTAMDMVANRLLDAREKGWQQFDADRNTLRRTMGVASLGGATLDNEENYLIKKLFTALGALQIENQARI
>NZ_AP022605.1|WP_085192248.1|3726793_3728491_+|SelB-C-terminal-domain-containing-protein
MYVVATAGHVDHGKSTLVQRLTGMWPDRLAEEQRRGLTIDLGFAWADIGGREMAFVDVPGHERFVANMLAGVGPVPAVMFVVAATEGWMPQSAEHLTALDALGVRHTLLVVTKADLADPGSAVTQALEAFAATGMANPPVAVSTDLDGVRAALVGLVDRLPTPDDAADVRFWVDRSFTVRGAGTVVTGTITAGTLRVGDELDHSGQRVTVRGLQSLGQQRSAVGPVARVAVNLRGVDRQEIGRGDALRTPGAWLDTDEVDVALRGADDLHRQLVLHIGSAAVPVRVRPLGAAARLRLARRLPLRVGDVGLLRDPGQHRIAAGVVVLDVRPPPLRRRGAALERAAELAAGRTRPPLCARASDLRAMGLPQTGRRVGAWVVDETWWAQRREHAVAAVRRWSADHAVAAGMPLETLRRETGLPSPELVAPVLADTALEVSGGRVREPGMTLPPRVDEAVRAVEDSLAADPFRAPDAQTLAALGLGAPELAAAVRTGRLTRIADGVVLGADALQRAAEILAALPQPFTVAEAKHALGTTRRVAVPLLEQLDAQRITRRETGGTHTVTQR
>NZ_AP022605.1|WP_085192257.1|3738560_3739775_+|cupin-like-domain-containing-protein
MLSRCIATDPHRFAAEYWGRRPLLSRCGALPRDFGDLLSSDMVDELIAERGVRAPFIRLAKEGDVLAKDCYLGPAGFGAEMPDQVDSAKVLTQFAAGATIVLQGLHRLWPPVTGFVRHLVDDLGHPVQANAYITPPSNRGFDPHYDVHDVFVLQTAGQKRWVVHEPVHPHPLPSQPWTQHRDAVVERATGDPMIDTVLSAGDALYLPRGWVHSAQALDVTSIHLTVGVSPVTGVDVARAVVDALAGDPAFRASLPMGGDPGDRDDVITTVTKVMAHMVERMRDDSTALSGAAADRLTRKHTERTRPVAVRPLATLDAATHADTTRVRWRHGLIASVHITGDRIMLRLPDRTISFPSSCAQAVLALCRGSVADAGNLPGLDRSDGAVLIRRLLREAVVTPVPTTA
>NZ_AP022605.1|WP_085192258.1|3739771_3740659_+|sucrase-ferredoxin
MTPRRHTPCSDQSLRRGDPMYGTASAGSEWVLLELAGGWGPSAFMQSPAVVDPQLGRAIVRRVEGAKMRIAAIRRHGRRSTTPRWRWFVARAGIGSEALYCGEVDSPNDYLDLALDGSDGTPTSDPVVAVCAHGKHDQCCAVRGRGAIASIADAYPELAWECSHLGGDRFAATMLILPEGLCYGRVDSTDAVELVGLYLDGRLDNRYLRGRTSLPHAVQAAQHFARDKYGDDRIASLSPLTVEHTGHHHRVVLDGDSGPVEITLEEDWSEPLLSQCHAKVPGRVKIYHLVSMAPA
>NZ_AP022605.1|WP_085192259.1|3740766_3741606_+|nitrile-hydratase-subunit-beta
MSTAAERAAQLDLVARLKSAYPELPDAPTPDLLDHGRITAYLKPVHDVGGEPDAPMKYENKQYERWEEATYVICEVLAWRGIWLSEERRRIGNVDVGRAQYLGLPYYGRWLLAVARVLVEKHHIGLTELTERMVEVKARYAGGLAGRKADAQPKFAGDGSQVQRNEHHRHAVGKGDPQVYGGLAGQPKFAVGDAVRVRELPVLFYTRTPEYTRGATGVIATVAYESPAAEDETWDRADATPEWFYVVRFNQSQLWHGYTGTATDTLQTELPERWLEAAS
>NZ_AP022605.1|WP_099050281.1|3741680_3742340_+|thiocyanate-hydrolase-subunit-gamma
MVDEITDFEVLEIALRELCIEKGIFTAEEHRHFTEFAEQIGPTPAARLVARAWLDPGFKELALREPMTASKEVGVDWMEPTGFGTPSDFTAFQILADTPTLHHVIVCALCSCYPRPILGNSPEWYRTPNYRRRLVRWPRQVLAEFGLYLPDDVDVLVQDSNQKHRFMVMPMRPEGTDGWTEEQLAEIVTRDALIGVALPKPGVTTNVIVATRPAVHPID
>NZ_AP022605.1|WP_085192261.1|3742350_3742704_+|thiocyanate-hydrolase
MSAPEPIETLARIVDRGQVWSRMAVKYGVENPVPPWKTSLDGLCDALDHGVCGDAGIPTFKQRRDEEDELSSTVYADLPFPESQLVALAHSLLVRGVIDEAELQERLAAVRARLEAT
>NZ_AP022605.1|WP_085192262.1|3742740_3745311_+|DEAD/DEAH-box-helicase
MTTPLLGDPGDLSPLRARGSDPDELFASFAAWAEGNGTTLYPAQEEALIELVSGANVILATPTGSGKSLVATGAQYAALARSSAGHGRSYYTAPIKALVSEKFFALCGLFGAENVGMLTGDAAVNAAAPIIACTAEVLANIALREGADADIGLVVMDEFHFYGDPDRGWAWQVPLLELPRAQFLLMSATLGDVTFLREDLTRRTGRPTALVANAERPVPLFYSYATTPMHETISDLLGTKQAPIYVVHFTQASALERAQALMSINVCTKAEKAAIADLIGAFRFSSAFGSTLSRLVRHGIGVHHAGMLPKYRRLVEQLAQAGLLKVICGTDTLGVGINVPIRTVVFSALSKYDGTRTRLLNAREFHQIAGRAGRAGYDTAGTVVVQAPDHEVENLKQFAKVADDPKKRRKLVRRKVPEGMVPWSESTMTRLVDAVPEALHSNMRVSTAMILDVVARTGTSEATGDRSGDPFETMRRLLTDNHEPRKRQLQLIREAVGIARSLLQAGIIERVDTPDGRRYRLTVDLPRDFALNQPLSTFALAAIDVLDATSESYALDVVSVIEATLEDPRQILAAQLKKARGEAVAAMKAEGIEYDERIELLDDVSYPKPLAELLEHTYEVYLQSNPWAADGQLSPKSVVREMWERAFTFREYVSVYGLTRSEGAVLRYLSDAFKALRSGVPAAARTDAVSDIVEWLGELVRQVDSSLLDEWEQLTGPDQRLDAPVAVPARPRPLTGNERAFTAMVRNALFRRVELFARRDWTGLGELDGDSGWTSQRWAQVGDEYFAEHDDVGTGADARGPALLIFDRQPGVWRVRQILDDPAGDHDWGFDVEVDLEASDEEGAAVLRLVDAGRLD
>NZ_AP022605.1|WP_133055566.1|3745333_3745690_-|hypothetical-protein
MPAARELGTLSGMWIAAAILGVPVLVILAVSGYPAYGGGRSLAVAVVITALTCAVSWVVAVFAFASALSGTISGVLMAIVLFGAPAASVLVFGFLARRLVTDRTAAGDVATPTTSEQP
>NZ_AP022605.1|WP_085192264.1|3746351_3746738_+|DUF2267-domain-containing-protein
MKAHEFLAAVRDRGNYKDQAEAQRVTAAVLGILGERLAGGEPTDLASQLPQGIGELVAKAQDGAASFGVEEFLRRVAAAVDGSPETAQWDASAVLCTVTEAVTGGQLNQILTQLQPAYATLFGKPELS
>NZ_AP022605.1|WP_085192266.1|3747251_3748157_+|serine-hydrolase
MRRRLPKWTIRVLAITGAALLVTGCEAQVRGAPPATESAPLATVQAPPAQPAEPMDGFAGLDVRVRQATADAAASGAEIETAVLDRNTGATVSGGGNNPFPIASVVKLFIADDLLLQESEGKMALSAADRKSLDAMLRSSDDSAAQMFWDRSGGNAVIARVKARYGLAGTTAPYNGHWDVTQSTAGDLVRYYDMLLDGAGGLPPEQGDTIIGNLAQSTPTGTDGYPQRFGIPEGLYAEPVAVKQGWFCCWNGGNQLHVSTGTFGPERRYVMAIASLDPTGEAAARENITRAVKTMFPGGKV
>NZ_AP022605.1|WP_085192302.1|3748192_3749251_-|glycoside-hydrolase
MTWARRSLRRTVCGLVSAAVVVATSMASGHADPATDALSRLNELSQQAVQSRQAVTAAQREADARSAQQAAAVDRHRADLAAVELANTRLQPYQAAVDRVAAMNYMSGSDGQFAAVLTAGSPQQLIDQLSAQRTVGAGIADQMKDFRSARERAAATAQASEKSAADAGAAAESAAAVRAELQAKLSELLRQIAAAEAQYTALTPQQRAIVDNAPLPGVPPGDVAPPSAAAIPEIPEALPVGVAFEAGLQPNTIVAARAVSRQFPQIAEIDGVRPDTKPWHPSGLAIDIVIPNPGSPEGIALGDQILAFAMSNASRFGLQDVIWRGTYYTPAGPQASGYGHYDHVHITVTPRR

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_AP022605_1	1.1|611635|32|NZ_AP022605|CRT	611635-611666	32	AP014720	Arthrobacter sp. Hiyo8 plasmid pHiyo8-1 DNA, complete genome, strain: Hiyo8	273570-273601	6	0.812
NZ_AP022605_1	1.1|611635|32|NZ_AP022605|CRT	611635-611666	32	NZ_CP050100	Rhizobium leguminosarum bv. trifolii strain 9B plasmid pRL9b3, complete sequence	172608-172639	6	0.812
NZ_AP022605_1	1.1|611635|32|NZ_AP022605|CRT	611635-611666	32	NZ_CP050106	Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b5, complete sequence	293140-293171	6	0.812
NZ_AP022605_1	1.1|611635|32|NZ_AP022605|CRT	611635-611666	32	NZ_CP025017	Rhizobium leguminosarum strain Norway plasmid pRLN5, complete sequence	153334-153365	6	0.812
NZ_AP022605_1	1.1|611635|32|NZ_AP022605|CRT	611635-611666	32	NC_012854	Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132505, complete sequence	159282-159313	6	0.812
NZ_AP022605_1	1.1|611635|32|NZ_AP022605|CRT	611635-611666	32	NZ_CP053443	Rhizobium leguminosarum bv. trifolii strain CC275e plasmid pRltCC275eC, complete sequence	135358-135389	6	0.812
NZ_AP022605_1	1.1|611635|32|NZ_AP022605|CRT	611635-611666	32	NZ_CP025506	Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvE, complete sequence	285651-285682	6	0.812
NZ_AP022605_1	1.1|611635|32|NZ_AP022605|CRT	611635-611666	32	NZ_CP016291	Rhizobium leguminosarum strain Vaf10 plasmid unnamed6, complete sequence	233616-233647	6	0.812
NZ_AP022605_1	1.1|611635|32|NZ_AP022605|CRT	611635-611666	32	NZ_CP050111	Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b1, complete sequence	293324-293355	6	0.812
NZ_AP022605_1	1.1|611635|32|NZ_AP022605|CRT	611635-611666	32	NZ_CP054026	Rhizobium sp. JKLM12A2 plasmid pPR12A205, complete sequence	194749-194780	6	0.812
NZ_AP022605_1	1.1|611635|32|NZ_AP022605|CRT	611635-611666	32	NZ_CP022668	Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR3, complete sequence	173758-173789	6	0.812
NZ_AP022605_1	1.1|611635|32|NZ_AP022605|CRT	611635-611666	32	NZ_CP054036	Rhizobium sp. JKLM13E plasmid pPR13E05, complete sequence	36153-36184	6	0.812
NZ_AP022605_1	1.1|611635|32|NZ_AP022605|CRT	611635-611666	32	NZ_CP050088	Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b6, complete sequence	431284-431315	6	0.812
NZ_AP022605_1	1.1|611635|32|NZ_AP022605|CRT	611635-611666	32	NC_019957	Mycobacterium sp. JS623 plasmid pMYCSM01, complete sequence	267331-267362	7	0.781
NZ_AP022605_1	1.1|611635|32|NZ_AP022605|CRT	611635-611666	32	NZ_CP030772	Streptomyces sp. YIM 121038 plasmid pSSP121038, complete sequence	677211-677242	7	0.781
NZ_AP022605_1	1.2|611689|32|NZ_AP022605|CRT	611689-611720	32	NZ_CP013054	Sinorhizobium americanum CCGM7 plasmid C, complete sequence	60010-60041	7	0.781
NZ_AP022605_1	1.3|611743|32|NZ_AP022605|CRT	611743-611774	32	NC_021289	Burkholderia insecticola plasmid p1, complete sequence	1247006-1247037	7	0.781
NZ_AP022605_1	1.1|611635|32|NZ_AP022605|CRT	611635-611666	32	NZ_CP048284	Rhizobium leguminosarum bv. viciae 248 plasmid pRle248b, complete sequence	173841-173872	8	0.75
NZ_AP022605_1	1.1|611635|32|NZ_AP022605|CRT	611635-611666	32	NZ_CP030763	Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed3, complete sequence	742671-742702	8	0.75
NZ_AP022605_1	1.1|611635|32|NZ_AP022605|CRT	611635-611666	32	MH669013	Gordonia phage Skysand, complete genome	9331-9362	8	0.75
NZ_AP022605_1	1.1|611635|32|NZ_AP022605|CRT	611635-611666	32	MK977699	Gordonia Phage Lollipop1437, complete genome	10768-10799	8	0.75
NZ_AP022605_1	1.2|611689|32|NZ_AP022605|CRT	611689-611720	32	NZ_CP032343	Azospirillum brasilense strain MTCC4038 plasmid p4, complete sequence	195926-195957	8	0.75
NZ_AP022605_1	1.2|611689|32|NZ_AP022605|CRT	611689-611720	32	NZ_CP012917	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence	532274-532305	8	0.75
NZ_AP022605_1	1.3|611743|32|NZ_AP022605|CRT	611743-611774	32	NZ_CP010057	Hymenobacter sp. DG25B plasmid, complete sequence	109405-109436	8	0.75
NZ_AP022605_1	1.1|611635|32|NZ_AP022605|CRT	611635-611666	32	NZ_LR134450	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 8, complete sequence	34077-34108	9	0.719
NZ_AP022605_1	1.1|611635|32|NZ_AP022605|CRT	611635-611666	32	MN585980	Microbacterium phage Gina, complete genome	4421-4452	9	0.719
NZ_AP022605_1	1.1|611635|32|NZ_AP022605|CRT	611635-611666	32	MN586059	Microbacterium phage Teamocil, complete genome	4421-4452	9	0.719
NZ_AP022605_1	1.1|611635|32|NZ_AP022605|CRT	611635-611666	32	NZ_CP022568	Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK04, complete sequence	171910-171941	9	0.719
NZ_AP022605_1	1.1|611635|32|NZ_AP022605|CRT	611635-611666	32	NZ_CP035710	Sphaerotilus natans subsp. sulfidivorans strain D-507 plasmid pSna507_unt10, complete sequence	87978-88009	9	0.719
NZ_AP022605_1	1.2|611689|32|NZ_AP022605|CRT	611689-611720	32	NZ_CP021032	Rhizobium sp. NXC14 plasmid pRspNXC14b, complete sequence	445456-445487	9	0.719
NZ_AP022605_1	1.2|611689|32|NZ_AP022605|CRT	611689-611720	32	NZ_CP021028	Rhizobium sp. TAL182 plasmid pRetTAL182d, complete sequence	171885-171916	9	0.719
NZ_AP022605_1	1.2|611689|32|NZ_AP022605|CRT	611689-611720	32	NZ_CP013503	Rhizobium esperanzae strain N561 plasmid pRspN561c, complete sequence	163330-163361	9	0.719
NZ_AP022605_1	1.2|611689|32|NZ_AP022605|CRT	611689-611720	32	NZ_CP013509	Rhizobium sp. N1341 plasmid pRspN1341d, complete sequence	163330-163361	9	0.719
NZ_AP022605_1	1.2|611689|32|NZ_AP022605|CRT	611689-611720	32	NZ_CP013520	Rhizobium sp. N113 plasmid pRspN113c, complete sequence	163330-163361	9	0.719
NZ_AP022605_1	1.2|611689|32|NZ_AP022605|CRT	611689-611720	32	NZ_CP013493	Rhizobium sp. N6212 plasmid pRspN6212c, complete sequence	163330-163361	9	0.719
NZ_AP022605_1	1.2|611689|32|NZ_AP022605|CRT	611689-611720	32	NZ_CP013516	Rhizobium sp. N1314 plasmid pRspN1314e, complete sequence	161086-161117	9	0.719
NZ_AP022605_1	1.1|611635|32|NZ_AP022605|CRT	611635-611666	32	NZ_CP039340	Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence	883818-883849	10	0.688

1. spacer 1.1|611635|32|NZ_AP022605|CRT matches to AP014720 (Arthrobacter sp. Hiyo8 plasmid pHiyo8-1 DNA, complete genome, strain: Hiyo8) position: , mismatch: 6, identity: 0.812

aggtcttcgatgttcggatcgccgtcggcgta	CRISPR spacer
tcggcttcgatgttcggatcgtcgtaggcgtc	Protospacer
  * *****************.*** ***** 

2. spacer 1.1|611635|32|NZ_AP022605|CRT matches to NZ_CP050100 (Rhizobium leguminosarum bv. trifolii strain 9B plasmid pRL9b3, complete sequence) position: , mismatch: 6, identity: 0.812

aggtcttcgatgttcggatcgccg---tcggcgta	CRISPR spacer
cggtcttcgatcttcgggtcgccgatatcggc---	Protospacer
 ********** *****.******   *****   

3. spacer 1.1|611635|32|NZ_AP022605|CRT matches to NZ_CP050106 (Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b5, complete sequence) position: , mismatch: 6, identity: 0.812

aggtcttcgatgttcggatcgccg---tcggcgta	CRISPR spacer
cggtcttcgatcttcgggtcgccgatatcggc---	Protospacer
 ********** *****.******   *****   

4. spacer 1.1|611635|32|NZ_AP022605|CRT matches to NZ_CP025017 (Rhizobium leguminosarum strain Norway plasmid pRLN5, complete sequence) position: , mismatch: 6, identity: 0.812

aggtcttcgatgttcggatcgccg---tcggcgta	CRISPR spacer
cggtcttcgatcttcgggtcgccgatatcggc---	Protospacer
 ********** *****.******   *****   

5. spacer 1.1|611635|32|NZ_AP022605|CRT matches to NC_012854 (Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132505, complete sequence) position: , mismatch: 6, identity: 0.812

aggtcttcgatgttcggatcgccg---tcggcgta	CRISPR spacer
cggtcttcgatcttcgggtcgccgatatcggc---	Protospacer
 ********** *****.******   *****   

6. spacer 1.1|611635|32|NZ_AP022605|CRT matches to NZ_CP053443 (Rhizobium leguminosarum bv. trifolii strain CC275e plasmid pRltCC275eC, complete sequence) position: , mismatch: 6, identity: 0.812

aggtcttcgatgttcggatcgccg---tcggcgta	CRISPR spacer
cggtcttcgatcttcgggtcgccgatatcggc---	Protospacer
 ********** *****.******   *****   

7. spacer 1.1|611635|32|NZ_AP022605|CRT matches to NZ_CP025506 (Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvE, complete sequence) position: , mismatch: 6, identity: 0.812

aggtcttcgatgttcggatcgccg---tcggcgta	CRISPR spacer
cggtcttcgatcttcgggtcgccgatatcggc---	Protospacer
 ********** *****.******   *****   

8. spacer 1.1|611635|32|NZ_AP022605|CRT matches to NZ_CP016291 (Rhizobium leguminosarum strain Vaf10 plasmid unnamed6, complete sequence) position: , mismatch: 6, identity: 0.812

aggtcttcgatgttcggatcgccg---tcggcgta	CRISPR spacer
cggtcttcgatcttcgggtcgccgatatcggc---	Protospacer
 ********** *****.******   *****   

9. spacer 1.1|611635|32|NZ_AP022605|CRT matches to NZ_CP050111 (Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b1, complete sequence) position: , mismatch: 6, identity: 0.812

aggtcttcgatgttcggatcgccg---tcggcgta	CRISPR spacer
cggtcttcgatcttcgggtcgccgatatcggc---	Protospacer
 ********** *****.******   *****   

10. spacer 1.1|611635|32|NZ_AP022605|CRT matches to NZ_CP054026 (Rhizobium sp. JKLM12A2 plasmid pPR12A205, complete sequence) position: , mismatch: 6, identity: 0.812

aggtcttcgatgttcggatcgccg---tcggcgta	CRISPR spacer
cggtcttcgatcttcgggtcgccgatatcggc---	Protospacer
 ********** *****.******   *****   

11. spacer 1.1|611635|32|NZ_AP022605|CRT matches to NZ_CP022668 (Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR3, complete sequence) position: , mismatch: 6, identity: 0.812

aggtcttcgatgttcggatcgccg---tcggcgta	CRISPR spacer
cggtcttcgatcttcgggtcgccgatatcggc---	Protospacer
 ********** *****.******   *****   

12. spacer 1.1|611635|32|NZ_AP022605|CRT matches to NZ_CP054036 (Rhizobium sp. JKLM13E plasmid pPR13E05, complete sequence) position: , mismatch: 6, identity: 0.812

aggtcttcgatgttcggatcgccg---tcggcgta	CRISPR spacer
cggtcttcgatcttcgggtcgccgatatcggc---	Protospacer
 ********** *****.******   *****   

13. spacer 1.1|611635|32|NZ_AP022605|CRT matches to NZ_CP050088 (Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b6, complete sequence) position: , mismatch: 6, identity: 0.812

aggtcttcgatgttcggatcgccg---tcggcgta	CRISPR spacer
cggtcttcgatcttcgggtcgccgatatcggc---	Protospacer
 ********** *****.******   *****   

14. spacer 1.1|611635|32|NZ_AP022605|CRT matches to NC_019957 (Mycobacterium sp. JS623 plasmid pMYCSM01, complete sequence) position: , mismatch: 7, identity: 0.781

aggtcttcgatgttcggatcgccgtcggcgta	CRISPR spacer
tcgtagtggatgttcggatcgccgtaggcgtg	Protospacer
  **  * ***************** *****.

15. spacer 1.1|611635|32|NZ_AP022605|CRT matches to NZ_CP030772 (Streptomyces sp. YIM 121038 plasmid pSSP121038, complete sequence) position: , mismatch: 7, identity: 0.781

aggtcttcgatgttcggatcgccg-tcggcgta	CRISPR spacer
gggtcttcgatgtcgggatcgccgagcagcat-	Protospacer
.************. *********  *.**.* 

16. spacer 1.2|611689|32|NZ_AP022605|CRT matches to NZ_CP013054 (Sinorhizobium americanum CCGM7 plasmid C, complete sequence) position: , mismatch: 7, identity: 0.781

acgaccgagatctccttgtcgacccggtcgaa---	CRISPR spacer
acgaccgagatgtccttgccgac---gacgaggcc	Protospacer
*********** ******.****   * ***.   

17. spacer 1.3|611743|32|NZ_AP022605|CRT matches to NC_021289 (Burkholderia insecticola plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.781

ccgatgttgacgttcgcgcacgtcccggtcac-	CRISPR spacer
gcgatgttgtcgttcgcgcacat-caggccgcg	Protospacer
 ******** ***********.* * **.*.* 

18. spacer 1.1|611635|32|NZ_AP022605|CRT matches to NZ_CP048284 (Rhizobium leguminosarum bv. viciae 248 plasmid pRle248b, complete sequence) position: , mismatch: 8, identity: 0.75

aggtcttcgatgttcggatcgccgtcggcgta	CRISPR spacer
cggtcttcgatcttcgggtcgccgacatcggc	Protospacer
 ********** *****.****** *. **  

19. spacer 1.1|611635|32|NZ_AP022605|CRT matches to NZ_CP030763 (Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.75

aggtcttcgatgttcggatcgccgtcggcgta	CRISPR spacer
cggtcttcgatcttcgggtcgccgacatcggc	Protospacer
 ********** *****.****** *. **  

20. spacer 1.1|611635|32|NZ_AP022605|CRT matches to MH669013 (Gordonia phage Skysand, complete genome) position: , mismatch: 8, identity: 0.75

aggtcttcgatgttcggatcgccgtcggcgta	CRISPR spacer
aaggcccagatggtcggatggccgtcggcgtc	Protospacer
*.* *.. **** ****** *********** 

21. spacer 1.1|611635|32|NZ_AP022605|CRT matches to MK977699 (Gordonia Phage Lollipop1437, complete genome) position: , mismatch: 8, identity: 0.75

aggtcttcgatgttcggatcgccgtcggcgta	CRISPR spacer
aaggcccagatggtcggatggccgtcggcgtc	Protospacer
*.* *.. **** ****** *********** 

22. spacer 1.2|611689|32|NZ_AP022605|CRT matches to NZ_CP032343 (Azospirillum brasilense strain MTCC4038 plasmid p4, complete sequence) position: , mismatch: 8, identity: 0.75

acgaccgagatctccttgtcgacccggtcgaa	CRISPR spacer
gagtccatgacctccttggcgacccggtcgac	Protospacer
. * **. **.******* ************ 

23. spacer 1.2|611689|32|NZ_AP022605|CRT matches to NZ_CP012917 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence) position: , mismatch: 8, identity: 0.75

acgaccgagatctccttgtcgacccggtcgaa	CRISPR spacer
gagtccatgacctccttggcgacccggtcgac	Protospacer
. * **. **.******* ************ 

24. spacer 1.3|611743|32|NZ_AP022605|CRT matches to NZ_CP010057 (Hymenobacter sp. DG25B plasmid, complete sequence) position: , mismatch: 8, identity: 0.75

ccgatgttgacgttcgcgcacgt--cccggtcac	CRISPR spacer
ccgatgttgacgttcacgcccgtaatcaagcc--	Protospacer
***************.*** ***  .* .*.*  

25. spacer 1.1|611635|32|NZ_AP022605|CRT matches to NZ_LR134450 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 8, complete sequence) position: , mismatch: 9, identity: 0.719

aggtcttcgatgttcggatcgccgtcggcgta	CRISPR spacer
tcggcgacgatgtgcggctcgccgtcggcgct	Protospacer
  * *  ****** *** ************. 

26. spacer 1.1|611635|32|NZ_AP022605|CRT matches to MN585980 (Microbacterium phage Gina, complete genome) position: , mismatch: 9, identity: 0.719

aggtcttcgatgttcggatcgccgtcggcgta	CRISPR spacer
gagagcgcgatgtacgggtcgccgtcggcgtc	Protospacer
..*  . ****** ***.************* 

27. spacer 1.1|611635|32|NZ_AP022605|CRT matches to MN586059 (Microbacterium phage Teamocil, complete genome) position: , mismatch: 9, identity: 0.719

aggtcttcgatgttcggatcgccgtcggcgta	CRISPR spacer
gagagcgcgatgtacgggtcgccgtcggcgtc	Protospacer
..*  . ****** ***.************* 

28. spacer 1.1|611635|32|NZ_AP022605|CRT matches to NZ_CP022568 (Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK04, complete sequence) position: , mismatch: 9, identity: 0.719

aggtcttcgatgttcggatcgccgtcggcgta	CRISPR spacer
cggtcttcgatcttcgggtcgccgatatcggt	Protospacer
 ********** *****.****** .. **  

29. spacer 1.1|611635|32|NZ_AP022605|CRT matches to NZ_CP035710 (Sphaerotilus natans subsp. sulfidivorans strain D-507 plasmid pSna507_unt10, complete sequence) position: , mismatch: 9, identity: 0.719

aggtcttcgatgttcggatcgccgtcggcgta	CRISPR spacer
atcacgccggtgttcggatcgccctcggcggt	Protospacer
*   * .**.************* ******  

30. spacer 1.2|611689|32|NZ_AP022605|CRT matches to NZ_CP021032 (Rhizobium sp. NXC14 plasmid pRspNXC14b, complete sequence) position: , mismatch: 9, identity: 0.719

acgaccgagatctccttgtcgacccggtcgaa	CRISPR spacer
tcgaccgagatcaccttgtcgaccttctgctt	Protospacer
 *********** ***********.  *    

31. spacer 1.2|611689|32|NZ_AP022605|CRT matches to NZ_CP021028 (Rhizobium sp. TAL182 plasmid pRetTAL182d, complete sequence) position: , mismatch: 9, identity: 0.719

acgaccgagatctccttgtcgacccggtcgaa	CRISPR spacer
tcgaccgagatcaccttgtcgaccttctgctt	Protospacer
 *********** ***********.  *    

32. spacer 1.2|611689|32|NZ_AP022605|CRT matches to NZ_CP013503 (Rhizobium esperanzae strain N561 plasmid pRspN561c, complete sequence) position: , mismatch: 9, identity: 0.719

acgaccgagatctccttgtcgacccggtcgaa	CRISPR spacer
tcgaccgagatcaccttgtcgaccttctgctt	Protospacer
 *********** ***********.  *    

33. spacer 1.2|611689|32|NZ_AP022605|CRT matches to NZ_CP013509 (Rhizobium sp. N1341 plasmid pRspN1341d, complete sequence) position: , mismatch: 9, identity: 0.719

acgaccgagatctccttgtcgacccggtcgaa	CRISPR spacer
tcgaccgagatcaccttgtcgaccttctgctt	Protospacer
 *********** ***********.  *    

34. spacer 1.2|611689|32|NZ_AP022605|CRT matches to NZ_CP013520 (Rhizobium sp. N113 plasmid pRspN113c, complete sequence) position: , mismatch: 9, identity: 0.719

acgaccgagatctccttgtcgacccggtcgaa	CRISPR spacer
tcgaccgagatcaccttgtcgaccttctgctt	Protospacer
 *********** ***********.  *    

35. spacer 1.2|611689|32|NZ_AP022605|CRT matches to NZ_CP013493 (Rhizobium sp. N6212 plasmid pRspN6212c, complete sequence) position: , mismatch: 9, identity: 0.719

acgaccgagatctccttgtcgacccggtcgaa	CRISPR spacer
tcgaccgagatcaccttgtcgaccttctgctt	Protospacer
 *********** ***********.  *    

36. spacer 1.2|611689|32|NZ_AP022605|CRT matches to NZ_CP013516 (Rhizobium sp. N1314 plasmid pRspN1314e, complete sequence) position: , mismatch: 9, identity: 0.719

acgaccgagatctccttgtcgacccggtcgaa	CRISPR spacer
tcgaccgagatcaccttgtcgaccttctgctt	Protospacer
 *********** ***********.  *    

37. spacer 1.1|611635|32|NZ_AP022605|CRT matches to NZ_CP039340 (Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence) position: , mismatch: 10, identity: 0.688

aggtcttcgatgttcggatcgccgtcggcgta	CRISPR spacer
gatccgtcgatgttctgatcgccctcggccag	Protospacer
.. .* ********* ******* *****  .

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	175217 : 182238	11	Gordonia_phage(42.86%)	integrase	attL 169937:169979|attR 181535:181577
DBSCAN-SWA_2	552786 : 566944	12	Mycobacterium_phage(100.0%)	integrase,transposase	attL 554672:554686|attR 572065:572079
DBSCAN-SWA_3	974923 : 1016719	32	Bacillus_phage(50.0%)	transposase,integrase,protease	attL 993535:993551|attR 1022417:1022433

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_AP022605|175217:182238|DBSCAN-SWA
ATTAGTAGAACCAGCGACCGGCCTCGGCGAGGTCCTCGGTGCTTGCCTCCACCGAGTGCCCGATTTCCGTTAAGGGGATGGCTGTCTCGTTGGGCACCGACGCGAGCACCTCGGCCATGCCGGGATCGGCCGCGATCAGCGTGACCCAATGCTTGCGGCGCGCTGGCGTGATCTTGCCCTTTGTGATCGCGTCGTCGACGGATGCCTCGACCTTCTGCTGTGCAGCGGCGGCCGCGATCTTTCGGCCCTCCTGCGCGTCGTGGCGCAGCGTGGCGAGCGTCTCTGTGTCGATGACCTCAAGGCCCGCACGCTTGGCGGCAGCGGCCACTGTGGACGGCTTTTCGGGGTTGAGGCCCGCGGCCTGTGCGGCGAGGTCCTTGGCGGTGTCGAGTATCAGGTCAACGTCGGTCGCGTCGGCGGGCAGGCCGAGCGATTCGAGCAGCGGAGCGGCCTGGTCGTCATCGAATGTGAGTGCCATCGGTTTGTCTCCTCTTACGCGGGTAGGACGATGCGCTTGGCGGCATACGGGCGGTCGACCGCGAACGCCGGCACGGCGTAGGCCTGCACCCATGTCGAGCGAGTTGAGCGGTCGTCGTACACCTCGACGGTCAGCGGTGCTTCGAATCCGACTGTGCCGACCATGGCCTTTTCGACGACGTAGGCTTCCCCCTCGGGGATGCGCGGGTTGGCGAACATTTCGAGGCCGGCCGACTTGAGCATGTCGTCGAGGCCCTCGGCGTAGGCGGTGCGAAGCTGCCGGGCCTGTGTCGGGTGAACGATGAGCAGGTCGTGAGTGACGCCGAGCTCCTCGAGGTCGGCGAGTTCCTGCGCCTCTGCGATGTGGGCGGTGGGCCGGTCGGCGCTGGGCGTGATCGCGTCGAGCGGGCCGACGAAAACGAGCTCTTCCCAGTTGGCCGCCGGGATGACGGTGCCCACGCCGGCGGCGGCAATCGCGGCCATCGTCGCGACGTCGAGCTTGCGTGTGATGGTGTTTGCGAGCTGCGTTGTCTGCTGGTCCAGCCACGACACGTCATTGCGGGCGCGTTGCTCGTCGGTGATCTGGAACTTGCCGCCCCAATCCTCGACGACGGCGAGCTTGGGCTCGGGGTCGACGCCCTCGACGACCTTGTATTCCGCTCCGGGCGTGCGCTTCTCGATGCTGGTGGTGAAGAAGTCAGACGCCTGTACGACCGAGTAGAGCAGGCCACCGGCCTCGACCTTCGCGCCGAGCGGATGAAATAGGTTAGGCAGCAATACCTGATCGTCGGCGAGTTCGGCGATGCGGCTGCGCAGGATTGTGGGCTGTTTGAGCGCGACGTCGACGGTGAGCCGGCGACCGTTGAGCTCGGGAATGAGTGCGTTGGGCATGAGCGTCGAACCTTCTCTAGTAGAGGCTGATTTCGGCGTCGGTCGCGTCTGCTGCGTCGGTGACCGCGTAGCCGACGGCGAGACCGGCGGCCTTGGTTTGCGCGGTGCCGTTCGCGCCGACCTGGACCTCGGCGTTGGCGGCGATCGCGCCCGAGGCGGTCACCCGCACGACGCGGGAGTTTCCGCGTACCACGCGCACGAGCCCGCCGCCGGCGGCGTCGTTGCCGGCCACGGCGCATGGACGCTCACCCGCGGCGGCCGGGCTCACGGCGATGTTGCCGCCGCTGGTGCGATTACCGGCGATCTTGACGAAACGCTTGGCGGTTACCGCCCCGGTCGCCTCGGCGGTGAGGTCAGCACCGGGGTCGTACACCGACGGGCTGGCGATGGTTGTCGACATGTCAGACTCCAATCGTGATGCGGTTGGTTCGCCGCCGGCGGGCGGCGGCTACTTGCACGGCGCGTCGCCGCTCGGCGGCGGCGTGGCCGGCTGGGTGAAACGTACTGGCGGCGACGGTGACTCGCCGCGCGGCCGCCACGCCGTACAGGTTGGCAACGTCTTGCAGCGAGGCGAGGGTGTCGACGCCGGGTGCGGATGCGCCGAGCAGCGCGAGGCCGGTCAGCACGAGGGGCCACACGCGGCCGTCGGGGGCCTCGTAGTCCGTGAGCGCCTCGACGCTGCGGTCGGGGTAGGCGTGCGGCAGGAGCGTCGCGACGGCAGTGGGCACGTTCACGAGGTCGCCCACCAAGGTCCTGCCGCCGTTGACGATTCGCAGGTTGTCGACGTAGCCGAGTGCCGGTGATGCGTCGCCCATCGGTCCGACGTGACCGAGCTTGACCACCGGCTTACGCAGGACCCTGGCGCGGTGTGCATCGACGGCGGCCGCTAGGTCATCGGCGCTCACGGTCCAGTCTCCGTTGCTGATCTGCCAGGTGCCGGCATGTACGAGCTCCACGCCGCGGATGGTGCGAACGTCAACGGGCACGGCGCTCACCCCTGTTTCGAGGCACGTCGCTCGGCCTCGACGATGACGGCTGCCGCATCGAATAGCCACCGCGTTCCGGTGCGCCGAGCCGGTATCCGACGGCGGCGGGCGAGGTCACGCGCCCCGTTCGGCGTGATGCCGAGTATCCGCGCGGCGTCGCCGGTGCCCATGGTCGCATAGGCGGGATCGTGCATCGAGTCGCGTTGTGCCGCAAACTCTCTGGCGCTTTCACTCACGCTTTGCGTCGAATCGCCAGTTTTATCTGTCGATTTCCGCAGTTTCGCGGTCACCGCAGCGAGCCGCGCGGCCGGGTGCGATCGCTGCCCGGCAAGCAGCCTGGCGAGCAGGTCGAGGGCGCGTGCGACGTAATCGGCCTCCTCGGCGTCTAGCAGCACGCCGCTCACTGGCGTAATCACGGCGCACCGTCAGCGTCGTCGTCGAGGAATCGCATAAGCGCGCCGTCAAGTTCATCATCGTCGAGCGCCGGGCCGTCGTCGGTGTCGAGGCGTTCGCCGAACCGCGCGACCAACCGCGCGGCCCGCGCTCGCAGCACGTCGACGACGGGCTCGCGCTGCTCGTCGGTCAGGTTTTCGACGAGCACGTGCAAGGCGCGGACGATCAGGGCGGTGACGACGTGGCGTTCACCGGTGCCGACGAGCCGCCGGTAGACGTCACCCTCAAGCCGTTTGTCGCCGGTGAGCAACGCGACGTCGTACAGCAACGCGTGGTAGTCGCGGCGCGCGTCCGCGAGTCGGTCATCGGCGGTCTCGTCGGTCATGGGGGTCACTCCTCGGTGTCGGTCGGGTTGTGTAGCGGCTCGGAAAACGATCGGGCCGGGTGATCCGGCGGCGGTTCGGGTGCGGGGGTTGGTGGGCAGCGCCGCACGCATGGAACGTGCCGCAGAGGCGGGCCGCGGCGGTCGTCGTCGACGAGGCAGAACTCGCCCGGCTCAGCCACACGTCGGGCACGGGGAACTGAGTGCGTCGCGGTAGGCCTCGGTGATGGGTCGGCCGATCACGGTTGCACCTCCTGATCCGCGCGCGCGGTCGGTTGGTCACCTTCGGGTCCGGTTTGGTGTTGGTAACCACCCGCTTGGAGCAACCAGGGAGACACGTCCGTTCTGCACGTCAGTGCAGGACGGGAATGGGTTTTACTTGTGTGTTTTCCTTTGGTGCACCAACGGGGGTGCAGTCGAACTGCACGGCAGGTGTGCGGTCTGAGAGCCGTTAAACTGCACAAAAAACCGTGCAATTCAAGCACTCGCAACGTGCACCGATTCCGTGCAGTTTGGAAGCAGACGAGATGCACGGATTCCGTGCAGTGTGAAAGCTGCTGTGGTGCACGGAAACCGTGCAGTGCGCGCGCGGTCAGGAGCCGCCCTCGGGACTCATCCTGGGACGCAACACGATCGGCTGGCCGTACTCGGTCAACTCCCAGTCGGTGAACTTGCGACCGCCGGCCGCCACCACGTAGGCCCACCGCGTCGCCAACTCGCGGCCGTCACGCTCAAACCGGCGGATCACGAGGCGGTGTTCCTTGGCGGCGATCGCGAGGGCACGCCGAACTCGCTCCCGATTGCGGCCCCACCCGAGGTCACCGGAGACGCGAACCGGCGAGGTCTCGAACGGCTTGCCCTTGCTGTTCCCGGCACGGGAGAGCAGATACGCGAGCAACACAAACCCGTCGGAACCGAGCTCGCGCACTCCTGTGCGCACCAGGTCATCGCACAGGTAGAAGTAGCCGTCCCGCGGGCGGCCGCCGACTACGTGAATGGGGTGGCCCATCAGCGCATCGCCTGGCCGAAAACGCCGTCGGTCCCGCTGCTCTTGGGGTGCCGATACGGGTGCGTCATGCGCCGTTGCGGGTGGCCTGTTCGAGGTTCTCGATGAACTCGACGATCGCTGACTCCGGTACGAGCCGCCGGCGTCCGACCTTGCAACTTCGTAGCGCGCCGCTCGCCATCAGCGCGAAAACCGTGGATCGGCCAACTCCGAGCCTTTCCATGACTGTCTCGACGGGGTGAAGCCTGGCTGTGTGTTCGGCGGTATCCGCCACTGGTCCTCCATGGTTTCTGGAATGCGACACAAGGATGGTCTATAGTGCTGCTATGAACCTTACACAGATGTTCGTACATGCGTACGAACATGTCGCAGGATGTTGCATTGCCGAAAATTGACAAGGGCGCGAAGGCGTGGGAATTGACTCTGGCCAAGACTGTCGGCGATGCGGTCCAGAAGCGGCGCAAGGCCCTGGGATGGACAGGAGTACAACTCGCGGAACGGACCGCCGAGCTCGGTTATCCGATTACACGCGTTGCGATTTCCAAGATTGAGGGCAATAGCAGGGCCGGAAAGCTCGACATCGCCGAGGTTCTTATCCTCGCGGCTGCGCTCGACATTGCGCCGGTGCTGCTGCTGGCACCGGGCTTTCCAAACGAAGGCCACGTAGAAGCCCAGCCGGGGCATACCGTAGATAGCCGGCAGGCCGTCAAGTTGTTCTCTGGTTTGGGGGCCGAACTCATCGAGGCGCAGGCGCTCGCCGAGGAGGGCGAGAGGCGGTTGTCCCATTTGAGGGAGATAGCGGCTTCGCCAGACACCACGTCGGAACATCGCAAGCTATTGACGAGCGACATTAAGTATTCAGAGCGCACAGTGCAGACACTCCGCGACGACGTGGCGCGCAAGAAGCGCGAGTTATGGGGCGAAACCGACAGTAAAGGGCCTGCTGATGAGTAGGCGGCAGCTTCCTCCGCAGATCAAGAAGATAGAGGTGACGGAGCGCAAGACAGGCAAAAACGTTGTGCGCTATCAGGTCACAGTCGACGCCGGGATCAATCCCGAGACAGGCAAACGTCAGCAGGTGCGGCGACGATATGAGACCGAACGTGAGGCACGTGCTGCGCTTGCAGACGTCACCGAGGCCGCGGTGCGGGGCACGTTTGTGCCGCGTCGGGCCATCACTGTGCGCGAGGTGTGTGACGACTACGTCGCGGGCCGGCACAGGCTGCGGGCCACCTCGAAGGCGAAGCTGAGTTATGACTTACAACCGTTGATCGAACGGCACGGCGACGAGCCCGTGCAGCGATTGACCAAGGCGCACGTCGATGCGTCGGTGTTCGATCTGCTGGCCGGCGGCACCAAGACAGGCAAGGGTCGAACTCGTCGGTCGTGGAGTGCGGTCGCGGTCAACAAGTTCACGCAAACCGTTGCGATGGTTTTGGCCGGTGCGCAACGCCAAGGCCTCGTCCCGCGCAACGTCGCCGAGCATGTCGATCCGGTGGCCGGAGGGCATCGCAGCGTCGACACCTACACCGAGACGGAGGTTGCGACGCTGTTGGCGTCGATCGCTGATGATCGGCTCGGGCACGCGTGGGAGCTCGCGCTATGTGGTCTGCGGCGCGGCGAGATAGCCGGTCTGCGGTGGGCCGACGTCGACCTCCGCGGCAAGGCGCTGTCAGTCACGAACAACCGGGTGGACGCCGGCGGTACGGCAGTGGAAAATGACCCTAAGTCGGCTATGTCGCGTCGAACGCTTCCGCTGCCCGATCGGCTGGTGTCGGTACTGCGTGCGGCGAGGGCTCGCCAGGCCGCCGAGCGGCTGGCCCTCGGTTCCGACGGTGCCTCGTGGGATTACGTCGTGAGCAACGAGGCAGGCGAGCCCTATCACCCGCAGGTCCTGTCCCGGTATTGGCGTGCTGCGGTGGAGGCGGCAGGCCTACGGCCGATCAAGTTGCACGCGGCCCGACATACGGCGGCGACGGCCATGCACCTCGCCGGCGTGCCGGTCGCGGTGATCGCGGCGTGGATCGGCCATAAGGACGCGTCGCTGACCATGCGCCTCTATGCCCACTCTCAGGACGACGCTTTGAAGGCTGCCGGTGACACTTTCAACCGGGTTGTGACAACGTCGTGACACCGAGAGCGGGATTCGAACAGATCGAACTGCGTTGTCGCATTTCAACGTGGAGCCGATGACGGGAATCGAACCCGCGTATTCAGCTTGGGAAGCTGATGTTCTGCCATTGAACTACATCGGCCTTACCAGCTGACGCTGGTGATCACGCAGATTATCACCCAGAGCCGATACGCTCGTCGGGTGCTGCTCTCCGATCGTGACATCCGGGCCGAGATCGACGCCGGGCGGCTGGGCATCGATCCGTTCGAGGATAGTTTGGTGCAGCCGTCGAGCCTCGACGTCCGCCTCGACACCCTGTTCCGGGTCTTCAACAACACCCGTTACACCCACATCGACCCGGCCAAGCAGCAGGACGAGCTGACGTCCCTGGTCGAACCGCCACCCGGCGAGCCTTTCGTCCTGCACCCCGGCGAGTTCGTCCTCGGCTCGACCCTCGAGACATGCACCCTGCCCGACGACCTGGCCGGCCGGCTCGAAGGCAAGTCGTCGCTCGGGCGCCTTGGCCTGCTCACCCACTCCACGGCCGGCTTCATCGACCCGGGTTTCACTGGCCACATCACCCTCGAGCTCTCGAACGTGGCCAACCTGCCGATCACGCTGTGGCCCGGCATGAAGATCGGCCAGCTGTGCCTGCTGCGCCTCACGAGTCCGGCCGAGCATCCCTACGGCAGTGCCAAGGTCGGCTCCAAGTACCAGGGCCAGCGCGGGCCGACACCCTCGCGGTCTTATCAGAACTTCATCAAGCTGAGCTGA

Protein sequences of DBSCAN-SWA_1

>NZ_AP022605|175217:182238|179418_179574_-|WP_085189420.1|DBSCAN-SWA
MERLGVGRSTVFALMASGALRSCKVGRRRLVPESAIVEFIENLEQATRNGA
>NZ_AP022605|175217:182238|180297_181482_+|WP_085189424.1|integrase|DBSCAN-SWA
MSRRQLPPQIKKIEVTERKTGKNVVRYQVTVDAGINPETGKRQQVRRRYETEREARAALADVTEAAVRGTFVPRRAITVREVCDDYVAGRHRLRATSKAKLSYDLQPLIERHGDEPVQRLTKAHVDASVFDLLAGGTKTGKGRTRRSWSAVAVNKFTQTVAMVLAGAQRQGLVPRNVAEHVDPVAGGHRSVDTYTETEVATLLASIADDRLGHAWELALCGLRRGEIAGLRWADVDLRGKALSVTNNRVDAGGTAVENDPKSAMSRRTLPLPDRLVSVLRAARARQAAERLALGSDGASWDYVVSNEAGEPYHPQVLSRYWRAAVEAAGLRPIKLHAARHTAATAMHLAGVPVAVIAAWIGHKDASLTMRLYAHSQDDALKAAGDTFNRVVTTS
>NZ_AP022605|175217:182238|175708_176584_-|WP_085189410.1|DBSCAN-SWA
MPNALIPELNGRRLTVDVALKQPTILRSRIAELADDQVLLPNLFHPLGAKVEAGGLLYSVVQASDFFTTSIEKRTPGAEYKVVEGVDPEPKLAVVEDWGGKFQITDEQRARNDVSWLDQQTTQLANTITRKLDVATMAAIAAAGVGTVIPAANWEELVFVGPLDAITPSADRPTAHIAEAQELADLEELGVTHDLLIVHPTQARQLRTAYAEGLDDMLKSAGLEMFANPRIPEGEAYVVEKAMVGTVGFEAPLTVEVYDDRSTRSTWVQAYAVPAFAVDRPYAAKRIVLPA
>NZ_AP022605|175217:182238|176985_177570_-|WP_085189649.1|DBSCAN-SWA
MPVDVRTIRGVELVHAGTWQISNGDWTVSADDLAAAVDAHRARVLRKPVVKLGHVGPMGDASPALGYVDNLRIVNGGRTLVGDLVNVPTAVATLLPHAYPDRSVEALTDYEAPDGRVWPLVLTGLALLGASAPGVDTLASLQDVANLYGVAAARRVTVAASTFHPAGHAAAERRRAVQVAAARRRRTNRITIGV
>NZ_AP022605|175217:182238|178937_179354_-|WP_085189418.1|DBSCAN-SWA
MGHPIHVVGGRPRDGYFYLCDDLVRTGVRELGSDGFVLLAYLLSRAGNSKGKPFETSPVRVSGDLGWGRNRERVRRALAIAAKEHRLVIRRFERDGRELATRWAYVVAAGGRKFTDWELTEYGQPIVLRPRMSPEGGS
>NZ_AP022605|175217:182238|177575_177986_-|WP_085189414.1|DBSCAN-SWA
MITPVSGVLLDAEEADYVARALDLLARLLAGQRSHPAARLAAVTAKLRKSTDKTGDSTQSVSESAREFAAQRDSMHDPAYATMGTGDAARILGITPNGARDLARRRRIPARRTGTRWLFDAAAVIVEAERRASKQG
>NZ_AP022605|175217:182238|177982_178348_-|WP_085189416.1|DBSCAN-SWA
MTDETADDRLADARRDYHALLYDVALLTGDKRLEGDVYRRLVGTGERHVVTALIVRALHVLVENLTDEQREPVVDVLRARAARLVARFGERLDTDDGPALDDDELDGALMRFLDDDADGAP
>NZ_AP022605|175217:182238|175217_175694_-|WP_085189408.1|DBSCAN-SWA
MALTFDDDQAAPLLESLGLPADATDVDLILDTAKDLAAQAAGLNPEKPSTVAAAAKRAGLEVIDTETLATLRHDAQEGRKIAAAAAQQKVEASVDDAITKGKITPARRKHWVTLIAADPGMAEVLASVPNETAIPLTEIGHSVEASTEDLAEAGRWFY
>NZ_AP022605|175217:182238|176600_176984_-|WP_085189412.1|DBSCAN-SWA
MSTTIASPSVYDPGADLTAEATGAVTAKRFVKIAGNRTSGGNIAVSPAAAGERPCAVAGNDAAGGGLVRVVRGNSRVVRVTASGAIAANAEVQVGANGTAQTKAAGLAVGYAVTDAADATDAEISLY
>NZ_AP022605|175217:182238|179702_180305_+|WP_085189422.1|DBSCAN-SWA
MRTNMSQDVALPKIDKGAKAWELTLAKTVGDAVQKRRKALGWTGVQLAERTAELGYPITRVAISKIEGNSRAGKLDIAEVLILAAALDIAPVLLLAPGFPNEGHVEAQPGHTVDSRQAVKLFSGLGAELIEAQALAEEGERRLSHLREIAASPDTTSEHRKLLTSDIKYSERTVQTLRDDVARKKRELWGETDSKGPADE
>NZ_AP022605|175217:182238|181665_182238_+|WP_085189651.1|DBSCAN-SWA
MLLSDRDIRAEIDAGRLGIDPFEDSLVQPSSLDVRLDTLFRVFNNTRYTHIDPAKQQDELTSLVEPPPGEPFVLHPGEFVLGSTLETCTLPDDLAGRLEGKSSLGRLGLLTHSTAGFIDPGFTGHITLELSNVANLPITLWPGMKIGQLCLLRLTSPAEHPYGSAKVGSKYQGQRGPTPSRSYQNFIKLS

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
169937:169979	attL	NA	NA	NA	NA
WP_085189408.1|175217_175694_-	hypothetical protein	A0A142K9Z2	Gordonia_phage	2.6e-12	36.8
WP_085189410.1|175708_176584_-	hypothetical protein	A0A142K9Z4	Gordonia_phage	1.6e-52	39.5
WP_085189412.1|176600_176984_-	DUF2190 family protein	W8EH90	Mycobacterium_phage	1.9e-26	62.7
WP_085189649.1|176985_177570_-	hypothetical protein	A0A142K9Z2	Gordonia_phage	8.2e-29	43.2
WP_085189414.1|177575_177986_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_085189416.1|177982_178348_-	hypothetical protein	NA	NA	NA	NA
WP_085189418.1|178937_179354_-	hypothetical protein	A0A0C5AIA5	Mycobacterium_phage	1.4e-30	51.5
WP_085189420.1|179418_179574_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_085189422.1|179702_180305_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_085189424.1|180297_181482_+|integrase	site-specific integrase	G9FGY1	Rhodococcus_phage	1.3e-86	46.1
WP_085189651.1|181665_182238_+	dCTP deaminase	I4AZP2	Saccharomonospora_phage	4.2e-78	74.7
181535:181577	attR	NA	NA	NA	NA

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NZ_AP022605|552786:566944|DBSCAN-SWA
CGTGCCTGACGCTACCTTCGCGTGCCCTGATCTGACGACGTTCTGCCGCCTCGATGAGCTCGGGCTGCAGGTGACCGGACAACGCGTGGCACCCGATCGGGCGTTTCTGGCGTGCCGGATCACCGACGACGACTCGTGGTGTCGCCGTTGCGGCGAGCAAGGCGTCCCGCGTGACAGCGTCACCCGCGAGCTTGCGCACGAACCGTTCGGGTGGCGGCCCACGACCTTGCTGGTCACTGTGCGCCGCTACCGGTGTGCCGGCTGCGCGCATGTGTGGCGCCAAGACACCAGCAAGGCCGCCGAACCGCGGGCCAAGCTGTCTCGGCGCGCTGTGCAGTGGGCGCTGGAAGCCCTTGTCTGCCAGCACTTGAGCGTGGCGCGGGTCGCTGAAGCACTGGCGGTGTCGTGGAACACCGCCAATAACGCGGTGCTGGCCGAAGGCCAGCGGGTACTCATCGCCGATCCGGCCCGCTTCGACGGTGTGCGGGTGATCGGCGTCGACGAGCACGTGTGGCGTCACACCCGTCGCGGCGACAAGTACGTCACCGTCATCATCGACCTGACCCCAGTGCGTGACGGCTCCGGCCCGGCACGGCTGCTCGACATGGTCGAAGGGCGGTCCAAGAAAGCGTTCCAACAATGGCTGGCTGAGCGGCCACAAGAATGGCGTGACCGAGTGGAAGTCGTTGCCATGGACGGATTTTCCGGGTTCAAGACCGCCACCGCTGAAGAGCTGCCCGAGGCAGCCACGGTGATGGACCCCTTCCATGTGGTCCGGATGGCCGGCAACGCCCTCGATGAATGCCGGCGCCGTGTCCAGCTGGCCACCTGTGGGCACCGGGGCCGCAAGACCGACCCGCTCTATGCGTGCCGGCGCACCCTGCAGACCGGGGCCGATCTGCTCACCGACAAACAGAAGGCCCGGCTCGACGCCGTGTTCGCCGTCGACGCTCATGCCGAGGTCGAGGCCACCTGGACGATGTATCAGCGCACCGTGGCCGCCTACCGACACCCCGACCGCAAGACCGGCCGCACCATGATGGCCGCGCTGATCACCACGCTGAGCACCGGCGTCCCCCAAGCCCTGCAGGAGGTGATCACCCTCGGACGCACACTCAAAAAGCGGGCCGCCGACGTCTTGGCCTACTTCGACCGGCCCGGCACCTCCAACGGGCCCACCGAAGCGATCAACGGCCGTCTCGAGCACCTCCGCGGATCGGCCCTCGGATTCCGCAACCTCACCAACTACATCGCCAGATCACTGCTGGAAACCGGCGGATTCAAACCCCAACTACACCGTCATTCATGAAGAGCCCCTTTACTGATTTCGCCGCAGCGACCCGAGCCGAGCAAGTGGCTGCGACTGCAGTACCGCACTATGCCTCTGTGAAAAAAATAAGCTTTGGACACTATGGTTCCAATTCGGCACCATCGTTCTCGCCCCACGCGGTAGGCCGCTTGCGCCCACACCCCCGCAGCGACGATCTCATCAACCCCCCAATTCGACTCAGCCCCTGAACATAGCCTACGGGTCAGCAACGAGCCGTCGCGGCCAAACGGGCGTAGGCACGAGCAGGAACGCCGTCCCGGGTCCTCGCTGATCACCCAGCCCGTACTCGTCACTTCGAGAGACGCTCAACAGCCGTCGAAACCGTAATGGCTGCGGAGGGGGATGAATCGTTCTGACTCCGCCCGGTCCCGGCCACGCAGCACCCGCACCACCGCGGGCTTGAGGTTGTCGTAGCGGATCGTGCCGGCACCGCGCCGAAACTCTCGAAGGCAAGCACGTCTCCTTCCAGGAACGCTTCTTGGGCCTGGGTGGCAAAAGCCACATGGAAGCCTTACCGAGTGCGACAGGCGCATCACGAACATCCACACCTTGATCAACACCCCGGCGATGGTGGCGTAAAACTCGCCGAAGTCGACCTCGGCCTCAGCGCCGGGGCGTGGGTCTGGGGCACGATCACCTCAACCCGGTCCAAACCCAGCTCGCGCTAGCGGTGTGAATCGCCCTGGTTCTTATCGGGGCTGCGCCCGTCGATCGGAAGTGTCGGTGATGCCTACGATAACGCCTTGGCCGAGACGACCATCGGGCTCTGCAAGACCGAATGCATCCGCGCCGATTCACCGTTCCGGCGGGGCCCGCTGCGCAACCTGAGCGACGTCGAACTCGTCACCGCCGACTACGTCAGCTGGTACAACCAGCAGCGCCTCATGCACCGCCTCGGACGCACCCCACCCGCCGAAGCAGAAGCCGAATACTACGATCAATCGGACGCCAGCCAACCGGCCGGCTCACAGAATCCCGAGGGTGCATGAAACCCAGGATGGTTCAGCGGCCGCCAAGGGACAACTCGGGCGACTGTGAAATTCTGAGGCTAGCTCTCTAGTAGACGTCAACGCACCAGACGAAACGAACCGAGCTCCAACGAATTTCATGTGTGACCGAGAGTCACGACGTACGGCAGGTGGTCTTTTCAGGCAGCCCTTCAGTCAGCGTGAAGGCTTCTGCCATAGAGCCCAAAGATCACATGTCAGCAACTCCTCATCCGAGTACTCAGCCAGTTCGCCGGCGGGGCGCAAAGTTGCGAGTTCTGGAACCAACCAATCAGGACTCATGATGTTCTGCAATACAACGCCGGAACAGCGCTCGCGAAATAGTCTCTCCCATTGTTCGTTTCGCCAAGCATTGCAGTATGCGTTCGGCTTGACGGAGCCCCGATGCGCTGGACGTAGGTGCGCCCACGGCGCGAGGTCACCATGGTGCGGCAGAAAGGAGCGCGGGTCGTGCGCGCCGCTGTCGCTTGTGTACATATGTGTGCTGATACAAAAGACGCCGCCCGGTCTCAGAACGCGGATGACCTCGTCGAGGCACTTCTCGGGGTCGTTGACATGCTCGAATACCGAAAACGAATAAACGAAGTCGAAAGAAGCATCGGGCCATGGCATCGCATGCGCATCACCTTGTACCACGTTAAGGCGGCATCGCACCCGACCGATGTGCTTCTCCAGCTCATTCCAGTAGGACCGGTCGATTCCGGCAACTTTTCGAAGCACAGTCTTTAGTGTCCGTTTCGGGCCGTTGCGGCGGAACACGCGGAAGTAGGCAGCTAGATCGAAGCCTTGAACGATAAGGTCATAGTCGAGAGCTGTCACTGTGTTATGGCGACTGAAGTACTTCAATCTCAACAATTGCTGGCCCGCGCCAACTTCTAACATCGCCACGCCCTCAAGCGACAGTCCGAAGTGCTCGGAGGCTGCTCTCTCCATATCTTCGCATGTTTCCACTACGTTAGCGACATTGCCCGCGACGTCGGATGTTTTATGTCGGTACACACGCCAGAATTCTGACAGTGTGCCCACGCTTCCGCTGTTCAACGAGGCATAAGATTTCAGCGTGCCGTCAGACGGGTGCGGCGAGCCCATTGGGTACCTTTCTGAGCGAGGCGACACAACATGAAGATTGCAGCATCTGCCTGAGCAGAGGATGCAGAGTACCGCCAAACCTACACCAATCTAGGGCTTCGCGTAGACGCGAAGACCGAATTGCGCGGGCCCCTAGACTAGGTCAACTGTGGATCCTGACGGGCGAACAGTTGGGCGCCCACGCACGTCACGCTGTGAGCACCGTAACCCGCGAAAACCGTCCTACTCAGAGATCTCACGGCCGGCAACAGAGCTGGTGCGCAACCGGGTCCGGGAGCGGGTGTGGGAGTTGATCGAGGCTCGCATGGCGCGGTCCCGCCCTCGCGGACCTGTTATGGGGACCTGGGTGGTGTGGTGGTCATCCGCATTGACGCCTCGCTGGTTGCCTCGCACAGCGACAAGCAGCACGCTGCGGGCAACTTCAAGGGTGGCTACGGGTTTCCCCGCTGACCGCGTGGTGCGACAATACCGGTGAACTGCTGGCGGTGATCGCCCGCCCGGGTAACGCCCGGGTCGAACACCGCGACCCATCACATCGTGATCATCGACGCGGCGGCCGCGCCGCGGTGGCGGCGCAACCTGCTGGTCACCATCGAGGGGGCGGGTTCCAGCCACGCGGTGGTCGAGCACCTGGAGAAGCTGAACACCCGCCCGGTCTGGTCGGTGGGCTGCTCGGTGGGGTTCGACCTCGACGAGCGGGCCTCGGTCGCGATCGGGCAGATGCCCGCCGCCGGGTGGGAGGCGGCGCTGGATGCGGCCGGGCAACGCCCGCGACGACGCGGCCGTGGCCGAGCTGACCGGGCTGCTGCGCGAGGGCGCCGACGGCCGGCTGGCCGGCTGGCCGCCCGACATGCGCGTCCTCGTGCGGCGGGAGAAGATCGAAGAAGGCCGCCAGCTGTCACTGTTCGAGCAGCTCAACGGCTACCGCTACCAGCTGATCGTGACCAACACCCGCGGTGGACAGGCCCAGCGGCTGGAGGCCCGCCACCGGGTGCATGCACCGGTTGGAGGGGTTCATCGGCTGCGGCAAGGACACCGGCCTGGCCCGCTGGCCCTCGCACTCGTTCGCGATCAACACCGCCTGGGTCACCGCGGTCGCCCTGGCCATCGACCTGCTGTGCTGGACGCTTTAGGTGGGCGTCGCGAATTCGCTCGCTTCGCTTCCGGTGTTCGGTGCAGGCCATTGCGTCCCCTTTAGGAGAACGGGCAATTCCCAACATCGGAGCAACTCAACATCAAACGAGCGCACCGCGAAAAATCCTCTCCCTACACCGCAAGTACACACGTGTGGTCCACAACTACACACGTGTGGTCGACGGCCGAACTCTGGGTTATGTTTACGGGCATGGGTCCGCGATCCCACCTCCGTGCGCGAACCTAGGCATAACGAAGCGGCCGGGACGAGCGTGGTGCCGACAAGCCTCAGCGCAGTCAAAGCCGTCGACTCTATGGAAGGCAGTGCACCACGCACCGTGTCTCAGACTGGAGAAGCACCTGTGCGGGCGAAACCGCAAGAACAGCGAATTAGCATGCGCGGGGGCACTCGGGGCACTTTGGCACAAGGCTGCGCGAAATTAGCTCGCCGCCGAGCGATCTCCTTCAACTCACATAGTGATCTGCCAGTCGAAGTAGCTCAGCGTAACTTCCCCGTCGCGCCGTTACGCGTCGTGCGTATTGGGTCCCGCTAAACGGAGGGAAAAAGATGCCGCGCATCAGCACTAAGCTCGTCGCGCCTGTCAGAGGGCTAGCAACTGGAAGCTCCTTTCAGGCATTGGTGGTGTTCGCCCTGAAGGCTGCCGGCGGTCTTTCTGGATACCTGTTATTCGCACTGATAGCCCGTCAGTCCGGCGTGGAACAGTTCGGTATGTTCAGCGTACTTTTCAGTGCGGCCATGATGGCCGGCATGGCAGGTTCGATGGGCCAGCAAGTCTTCCTCGTCAAGGAGATCCCGAAGGCACAGCACGCCGAAGACTCGCGTTTGGAGATGCGAACCTATGCTTTCTCGTTTGTATCGACAGTGATTGGGTCGGCAATCGCCGGGATCGCATTTTATGCGGGCGCCACGATTTTTTATCCTGACGCCGCAGCCTCGGTCGCTATAGGGGGCGCGCTGCTATCAATCACCTTCGCCGTTTCACAAACGACCCTAGGCGCCCTGAGGATACAGAATCGGGTGGTCTTGGCGGTCGCAAGTCGCGACGTGATTTGGCGCATTGCTACAGCAATCGTTATCGCCTGCGTCCCCTGGTTGATGCCAACACACGCTGTAGACGCCGGTTCAGCCCTGGTTGTAATGGGGGCAACGCTTCTCGTCATCGTCCTGTGGCATGCCATTATTCTCTCGCGGAAATTCAAGGTAAGGATATCTACTCGCGGGATCCTATCCCGACAATGGCTGCAATTGACGGCTGGCCTGACACTGGTTGCCGTCATTTCGAGCGCCGACCTCTATATCTTTTCCATTGCACTAGGAGTATTAGTTCCTCCGGCGGAGGTCGGTCCATTCTTCGCGGCGATGAAAACCGTTGAGGTCATCAATCTACTTCTTATGTCGGTCGCTCTAGTGATGGGCCCACACATAGCCCGTGCTATCGCAGCCAAGGACTTACGACGTGCTCAAGCAGAATGCAATACAGCAATCGTGGTTCAAGGTCTACCTTCTGTGTTCGCCTGCATCGCAGTTATCTACTTCGCGCAACAGCTTCTGGGATTATTCGATCCTATATTCGCGCAGCATGCCGATGTTCTGTACATTTTGACCGCGGGCGTATTAATCAACGCCCTCGCTGGCCCAACAGTACTCATGCTACAGCTCGTAGATTTACACTGGCGTCAGGTCGTGCTGCAGGGCGGCAGCCTCCTGGCTGCACTTACCTTACTTCCGGTCGCAGTAGACCACGCTGGTCTTGTAGGTGCAGCATACTGTTACACGCTATCGAAGTTGGCGTGGAATTTCGCCGCTGTCTTGTCATGCCGCAAACACGCAGGGATTGATCCGTCCTGCTTCGGCGTGTTCGGATTCGGCGCCTTGAATTGTAGAGAGAGTTTACGCGAACTTTGCAACCGGTTAGCGAGAATTGTGAATGATAAGCACAAAATTTGAAACGAACACTGAACCGTCTACTTCGATCAAGGTGTACCGACTCACGGATGGCAACCGTCCAACGATACATCGCTTCTACGACACGTCACCGGTCAGCCCATCGGGTCGCTACATCGCTCTCACAGAATTTCCATATGACGACCGACTTCCGGTCCCAGGCGACCAAGCACGCGTTTTCGTGCTTGACCTCGAGACCGCCGAAGAGGTGTATTCCACCCTCACGTCGGCGTGGGATACCCAGGTAGGCGCACACGCGCAATGGGGTGACACCGACGATGCACTCTACTTCAACCGTTTAGACTCCGCAGACTGGAGTCCATATGGCGTTAAAGTCGACTTCATCGCACGTCGAGAGGATCGGCTCGATACCACCGTGTACATGGTTTCCCCGGACGGCAGCGCGGCACTGAGCCCATGTCTCCGACGAATCGGGATCACGCAGCCAGGCTATGGCGTAGTCGTGCCGACCGATCGAATCAAAACTAACCGTGGCGCATCCGCAGAGGATGGACTCTACTCGACCGATACAGCATCTGGCCGCTCTCGGCTATTGATCAGCTTCGCCGATTTGATTAGCCAGGCAGGCATCCGGCAGGGGCAGAGCCATTCATCCGGTGCTTTTTACGGCTTTCACACGAAATGGAACCCACAGGGCGACAGGGTGATGTTCATAGTGCGGTTCGCACCCGATTCCGCACGAGTCGGAAAGACCGAGAACTATCTCTTCACCCTCGCCCCTGATGGACGGGACGTGGCGTTAGCGCTCGGGCCTGATGAGTGGGAAGGTGGTCATCACCCCAACTGGTGCCCCGACGGGCGGTCAATAGTAATGAACCTCATCTTCCCACGTCCCGCAGGGTGGCGGATGAGCTCGTCGACTCTTGCGGGCCGAATAGCACGCCGGCTGGGATTTCGCTACTTTCCCCGAGCTCGCCGACTGTCCTTCGTGAGGATTGATCACCGCGGCAGAGAGACTCGTATCCTTGCCCCCTCCAGCGTCGGATCCGGGCATCCCACCGTCGATCCTTCCGGAAAGCTCCTCATAACGGACGCATACCCGAGCGAAGAAGTCGCATTCGAGGACGGCACAGTCCCTATCCGTGCCATCGATATTGCCGCCGATGTAGAAACATGCCTGCTCCGCGTCAACACGCGACCGCAATTCGTGGGTCGCAATAATGAGTATCGGATCGACCCTCACCCCGCTTGGGATCGGAGCGGCAAGATAATAACCTTCAACGGATCGAAGGACGGGTGTCGGTCGGTGTTCCTCGCAGATCTAAGCCCCTTCATCGACAACCTCCAATCGGACTCGTGAACCGCCCGACGTCGTTCCTCAGCGTAAAAACGCAGTTCGAGAACGCTGGTGACGCACTCATAAACCGCGAGTTGGTGCGGATCTGCTCCCGATTCTCGGACGTCGTTGTCGACACGAGTCGGTGCCCTGACGCCTTTCTAGCATCGATGCACCTCGAAGAATATTCTCCGCATGTCAAAAAAGCGCGGTCCGCGTCGCTATTCTTCACACTTGTACTCCAACGTGTCCTCAGAAGACCCGGTTACTACTTCCTGATTCCTGGAGGCTATGTCGGCGAGAAACACGGTATACAACTACTTAGCTTGATAGCGAACACCGCCATTCTCGCTGGCATGAAGCTCCTCGGCGTGCGCGTGTGCCACGTGGGAGTGTCGTACGAACGACTCGGTTCCCGGCACGCACGAATACTGGCGTTGAGATCTCGCCTCATGCACTGTCTCCTCGCCAGGGATGCCAGTAGCCGCGCATATGCAGAGTCTTTGGGAATCAGGATCGATGGCCTCATACCTGACCTCGCGTTCGGCGCAGTTAGTTACCGATGCGACATCTCGGGCAACGAAGGTGTGGCACTGTCTTTTCGCGTCGACCAAATGGATTCGCAACGTTCAGACGCCGAACTTCTTATTCGACATCTCGACGAGATCCTGCCAAAGTCGGCTGATTTCAAGTTCATTGCGCAGGTTCAACGGGATGCACCCTTCATGCATGAGCTCGCTATGCGCAAGTATCCATCAGGAAGGTCTTCGTCATTCCGCGCTACTTTCTCCGACGCTGACGAAGCGTTGGACGCATACGCAGGCTGCAAGTACGTTTTGTCCAACCGCCTTCACGTACTTTTATTTGGCATGATTGCTGGGTGTGAGCCCATCCCATGCGTCGACGAGACGGTGAATCGGAAGGTAGTTGGCATCTTTGATCTATTAGGCATTCGGCCTGTTCGAAGTACGGATATCCCTGAAGGTTTGGGACGTAGCCTCTCTCAAGCAGGCAATCTAGGAAGCGTGCAAATTTCTTCAATCGTGGCGTCACAGGAGAGAGCTCTGCACAAGGCTTTCTCGGCCGTCTTCTGCAACAACGTATCGGAGGCTGTATGACCGGAGATGCTGACGTGATTCTTCCCTTGTTCTCAGTGGTTGTTCCTTGCTTCAATAGATCAGCCGAAGTGAAACATACCCTGCACTCGATACGTGCGCAGACCATCGAAGAAAGCTTCGAGTGCATAGTCGTCGATGACGGTTCGACCGATGCGCAACAGTTGTGGGACACGGTGAAGTCCCTAGATGACTCTCGCTTCCGGTATGTTCGCCAATCCAACCAGGGCGGCGGTGCCGCGCGAAATACCGGCATCAAGCTAGCTCGAGGGCGCTACATTGCCTTCCTGGATTCAGACGACGTTTTTCTTCCTCAGAAACTCGAGCGCGTTCGAAGTTTCCTGGAAGAAACCGGATGTGAAGCCGCGTACTCCCTCGCCTATGTCGATCGCGGTGTTCCGGGAAGCCTATGGCTCAAGCCCGACCGAGGCATACGCTCCAACGAGGATATGGGTGAGTATCTCTTCGTCTCCAACCAAGTTGTACAGACATCGACGATCGTAGTAACGACGGAGGTTGCGAGGAGAGTCATGTTTGATCCGACTCTGCGCAAAGGTCAGGATCTCGACTTCTGCGTACGTGCGCATGCAGCGAATGTGCGCTTCACCATGATTGATGAGCCACTTATTATCTGGCGTGACGCTACGGAGATCGGGCGAACCTCACGGCATTCCGGCGCCTCCGGGCTCCTTGTCTGGCTGGACAAAAATCAGTCGCTACTCACTCGAAAAGCCTTTCTTGGGTACCGCGCGACTGTCGTAGCAGTGTTCCGTCCTAAATGGCAGTTTCCAGTCGTCGCTCGAGACTTGATTCTCGGCATGTTGATCGCGAGGGTTCCGATCCGAGTGACTTTGCGCCAATCACTTCGCTTTGCTCTACCGCGATCGGTATACCGACGACTGGTCGACCTTGTCGTCAGGCTTCGCGGCAGGGCCCTCGACGACCACTCCGTTTCACCGATCCTGAACAGACGGTCGGCGCAGTCTTGTTGAGTCACGGCGCGGCGGATTCGGCGAGTCTGCTTGTCGACCTGGATCTTTCACGTAATTGGCAGTCGATGGGTGTCGTGAATGTGAAAGGTGCGCTGCCTCAAGGATAATCATGGTTTCCATGCCGTAGCTATCCGAGAAGGGAGCGCACCTGACAGATGCACGATAACAGTGATTGGTCGAAGAGTCTGCGTGTGGAGGTGCGCGGCGGCGATGTGGTCGGGCATGCCGGGAACGTGATTCCGCGGATGCTCGCCGACGCGACCGGACTTACCGAGGCGTTGTCGGCGGCGGTGTCGCGGCCGGAGGTGACCCACGACCGGGGCGCGGTGTGGCGCGACGTGGCGGTCGCGATCGCCGGCGGCGCGGAGAACCTGGCCGGGTCCGCGGTGCTGCGGGATCAGGGGCGACTGTTCGGGCCGGTCGCGTCGATCCCGACGATGTGGCGGTCGCTGAACGAACTCGACCACGCGGCGCTGGCGCGGATCGCGACGGCGCGCAACAAGACCCGGAACGGGTGTGGAGCTGATCGCGGCACGGCACGGCCGGATCCCGCCCGCGCACCTGCTACGGGGATCTGGGGCCGGTGATCGTGATCCGCATCGACGCCACCCTGGTCACCGCGCACTCGGACAAGGAGTGCGCGGCCGGGAACTTCAAGGGTGGCTACGGTTTCCACCCGTTGACGGCGTGGTGTGACAACACCGGGGAACTGCTGGCGATCATCGCGCGGAAGGGAAACGCCGGGTCGAACACCGCCGAAGACCACGTCGCGATCATCGACGCCGCGGTCGCGGCAATCCCGGCGCGGTGGCGGCCCAACCTGCTGGTCACCATCGACGGCGCCGGGTCCAGCCACGCCGTCATCGAGCACCTCACCGCGCTGAACAACCGGCCGGGCTGGTCGGTGGCCTATTCGGTCGGGTTCGATCTGGACGAGCGGGCCCGCACCGCGATCGGCCACACCCCCGAGGATGTGTGCTCACCGGCGCTCGACCCGGCCGGCGATCCGCGCGAGGACGCTCAGGTGGCCGAGCTGACCGGGCTGCTGCGGGACTCCGCCGGCGGGGACCGGTTGGATGGCTGGCCCACCGACATGCGGATCCTGGTGCGGCGGGAGAAGATCGAGCACGGCACCCAACTGTCGCTGTTCGAACAACTCAACGGATACCGCTACCAGGTGACTGCCACGGCCACCCGCGGCGGGCAGGTGCAGCGGTTGCAGGCCCGCCACCGGGTGCACGCCCGCGTCGAGGGGTTCATCCGCAACGGCAAGGCGACCGGTCTCGCCAGGTGGCCGTCGGCGTCATTCGCCATCAACACCGCCTGGGTCACCGCCGCCGCCATCGTGATCGACCTGCTGTGCTGGACCCGGCTGCTGCTCCTCGACGGGCCGCTGGTCAAGGCCGAGCCGCACACGCTGCGTTACCGGCTACTGCACGCCGCCGCCCGGCTCGTCTCCCACTCCCGCAAACTGATCCTGCGGATCCCCGAAACCTGGCCCTGGGCGCAGGAATTCGCCGACGCGTTCAACCGCGTCCTGGCCATCCCCTGACGCACCGCGCCGTTGTCACGACGACCCCAAAGTGACGACCCCAAAGTAAGGAGCGAACCACCCACCGGGACCGTGGAACCCGGCGCCACCGCACGACACGCGGCGCCGAGACATACCCGGAACCATGAAATCAAGATCAAGACGGCCGGTCAGCAACCGCCACCGTCCAACCCGGCCTACCGTGAAATTCTGAGGTCGATTGCCGCGTTCATTGAGGTTGACCCCTGATGGTGGACACGGGGTCAGGCGGCTTGTGCCGTCTGATTGTGGCGGTCCTCGAACTCGACTGGGCTGATCATGCCGATCTTCGAGTGCCGTCGTCGGCGGTTGTAGACCCGTTCGATCCAGTCGCCGACCGCCAGCCTAGCAGCAGCCTTGGTCGGCCAGGTGTAGCGGTTGTAGAACTCTGATTTCATTGTGCTCCAGAAAGATTCGGCCTGAGCGTTGTCCCAACACACCCCGGTCCGGCCGACCTATTGGGCGATGTCGTGAGCGCGGGCGAACCGGGCGAGCTGCCCGGAGGTGTACTGGGTGCCGCGATCGGCATGGAAGATGACCTGCCCTGGTAAGTGCCCGCGCATGGTGACCGCCATTGACAGCGCGGACTCCACCAGATCGGTGCGCAGGTGATCCTCCACCGCCCAGCCCAGGACCCGCCGCGAGCACCCGTCGCGGACCGCGCACAGAACAGCCAGCCCTCATCGGCGGCCAGGTAGGTGATGTCCGACGTCCAGACCTTGTCGAGCTCACCGCGGTCGAATCGGCGATCCACCAGGTCCTTGGGTCGATGCGCGTCCAGGTCGACGACCGTGGTGACCGGGGTGAACTGCCGCGGGGGTGATCCCGGCGATCTGCTGGCGCGGCGCATCGAGGCCGCCACCGTCTTGCGTGAGATCACTTCTCCGTCGTCGCGCAGATCGGCCAGGATCCGCGGTGAGCCGTACACCTGATCGGAGGCGTCGTGGAACCCCTTGACCTTCGCGTCGATGACCTCACGGCGCTGCTGGGCCGGCGAGGGCCCCGCCACCTGCGCCGCGCGCCACTTGTAGAAGCCCGACCGCGACACCTCCAACAGTGCAGTCATGCCGATCACCGTGAACTCGGCCTTCTCCGCCTCGATCAGCCGGTACATCTCTACCGGTTCTGTTCGGAGGCGAAGAAGGCCGCGGCTTTTTTCAAAAACGCCCTGTCCAAACGTAATTCAGCATTCTCCTTGCGCAAGCGGTGCAGCTCTGCGCGTTCATCGTCATCGAGCACCTCGGGATTATCGGCTGCCAAGCGCGCTTTGGCCGCCGCGACCCACCGGCCGAGCAATTGTTCTCCAACGCCGATCTTCGCGGCGACGTGCGCGATCGGGCGTCCGGTATCGACGACCAGACGCACGGCCTGCTCGCGACACTCCGGGGTGTACTTCTTGCGGTTTCCCGACACGGGAACATCCTCCCCCGCAGGACCAGCAGTCCCGCGATCAGATGTCCACCTTCAGGGGTCAACCCCATCATGGGACCGTTTGAGGTGGTTTGCACCGTCATGGGACCACCTGGTTTGCCGGTATGGCTTTTCGCAGTTGAGGGTGTAGAGGTGGTCGACAAGTCGCTGCGGGGGTAGGGGTGGAGGTCTTCCGATGCCCAGGACTCCCGACATGGAGTCCGGGTCCCGGTCGGTATTTTTGTGGTTTGATCTGCGAGTTTCCGGCTGTGTCGTGTCGTGGTCCCGGGCCTCGTGCGAAATAATGGATAGCTGTTGCTGGCGATCTGGGGTTGGTGGACGATGGCCGTGATGACCGCGCAGCCGCCGCTTCCGCTGACGCCGCGGAATGCCCGCCCGGTCGGCGCGGCTGCGGCGATCGTCGAGGACGACGCCGGTGTGCCGATGCTCGTGGTTGTACCAGTTGGTGAAGGTGTTCATGAATCGCCTTGCCCCACTGACTGACCCGAAGCGTTCAGGAAATTGCGGCCCGTACTTCAATGTCTTGAACAGCGACTCCGAGTACGGGTTGTCGTTGGACCCGTGGCCGCGAATGCGACCGGATGACCTCCAGATCGGCGAGCAGCGCGGCGACGGTCTTGCTGGTCATCGACGTTCCCCGGTCGGCGTGCACGATCTGCGGTACACCATGCCCCGTGAAGATCTGCTCCATCAGTTCCTTGGCCAGCACCCCGGATTCGTGGGCATGAACATCGACACCGACGATGTAGCGGGAGTAGATGTCGATCATCACGTAGGCATCGAAGTAGGTGCCCTTCACCGGCCCAGCGAGTTTGGTGATGTCCCAGCTGTACACCTGCCACGGAGCGGTCGCGACCAGCTCCGGGCACACCTTGGCCGGGTGCCGCGCCAGCCGGCGGCGTTCAGCGACTTGCTTGTTCTCGCGTAGTACCCGGTACATCGTGGACACCGAACACAGGTAGGTGCCCTCGTCGAGCAGCTGGGCGTAGATCTGCAACGGCGCGAGATCGACGAACCGGTCGCTGGTGAGCACCTCAAGGACCCGCCGCCGTTCCAGCTCGGTCAGCTTGTTGACCGGATCGGGCGCTGGTTGGGCCGCCACCGCGGGAGTGGGCGCGGTAGCGGCGGTGCGCCGCCGGTGCGCCGTCGAACGCACCATCCCGGTCAACCCCGCTGCCCGTCTCGTGGGCACACCGCCGGCGATCAGCAACACGTAGGTTTCGGTCAT

Protein sequences of DBSCAN-SWA_2

>NZ_AP022605|552786:566944|566209_566944_-|WP_099050096.1|integrase,transposase|DBSCAN-SWA
MTETYVLLIAGGVPTRRAAGLTGMVRSTAHRRRTAATAPTPAVAAQPAPDPVNKLTELERRRVLEVLTSDRFVDLAPLQIYAQLLDEGTYLCSVSTMYRVLRENKQVAERRRLARHPAKVCPELVATAPWQVYSWDITKLAGPVKGTYFDAYVMIDIYSRYIVGVDVHAHESGVLAKELMEQIFTGHGVPQIVHADRGTSMTSKTVAALLADLEVIRSHSRPRVQRQPVLGVAVQDIEVRAAIS
>NZ_AP022605|552786:566944|561722_562715_+|WP_085192581.1|DBSCAN-SWA
MTGDADVILPLFSVVVPCFNRSAEVKHTLHSIRAQTIEESFECIVVDDGSTDAQQLWDTVKSLDDSRFRYVRQSNQGGGAARNTGIKLARGRYIAFLDSDDVFLPQKLERVRSFLEETGCEAAYSLAYVDRGVPGSLWLKPDRGIRSNEDMGEYLFVSNQVVQTSTIVVTTEVARRVMFDPTLRKGQDLDFCVRAHAANVRFTMIDEPLIIWRDATEIGRTSRHSGASGLLVWLDKNQSLLTRKAFLGYRATVVAVFRPKWQFPVVARDLILGMLIARVPIRVTLRQSLRFALPRSVYRRLVDLVVRLRGRALDDHSVSPILNRRSAQSC
>NZ_AP022605|552786:566944|557913_559314_+|WP_133055578.1|DBSCAN-SWA
MPRISTKLVAPVRGLATGSSFQALVVFALKAAGGLSGYLLFALIARQSGVEQFGMFSVLFSAAMMAGMAGSMGQQVFLVKEIPKAQHAEDSRLEMRTYAFSFVSTVIGSAIAGIAFYAGATIFYPDAAASVAIGGALLSITFAVSQTTLGALRIQNRVVLAVASRDVIWRIATAIVIACVPWLMPTHAVDAGSALVVMGATLLVIVLWHAIILSRKFKVRISTRGILSRQWLQLTAGLTLVAVISSADLYIFSIALGVLVPPAEVGPFFAAMKTVEVINLLLMSVALVMGPHIARAIAAKDLRRAQAECNTAIVVQGLPSVFACIAVIYFAQQLLGLFDPIFAQHADVLYILTAGVLINALAGPTVLMLQLVDLHWRQVVLQGGSLLAALTLLPVAVDHAGLVGAAYCYTLSKLAWNFAAVLSCRKHAGIDPSCFGVFGFGALNCRESLRELCNRLARIVNDKHKI
>NZ_AP022605|552786:566944|559492_560632_+|WP_133055579.1|DBSCAN-SWA
MLDLETAEEVYSTLTSAWDTQVGAHAQWGDTDDALYFNRLDSADWSPYGVKVDFIARREDRLDTTVYMVSPDGSAALSPCLRRIGITQPGYGVVVPTDRIKTNRGASAEDGLYSTDTASGRSRLLISFADLISQAGIRQGQSHSSGAFYGFHTKWNPQGDRVMFIVRFAPDSARVGKTENYLFTLAPDGRDVALALGPDEWEGGHHPNWCPDGRSIVMNLIFPRPAGWRMSSSTLAGRIARRLGFRYFPRARRLSFVRIDHRGRETRILAPSSVGSGHPTVDPSGKLLITDAYPSEEVAFEDGTVPIRAIDIAADVETCLLRVNTRPQFVGRNNEYRIDPHPAWDRSGKIITFNGSKDGCRSVFLADLSPFIDNLQSDS
>NZ_AP022605|552786:566944|555278_556211_-|WP_085192578.1|DBSCAN-SWA
MGSPHPSDGTLKSYASLNSGSVGTLSEFWRVYRHKTSDVAGNVANVVETCEDMERAASEHFGLSLEGVAMLEVGAGQQLLRLKYFSRHNTVTALDYDLIVQGFDLAAYFRVFRRNGPKRTLKTVLRKVAGIDRSYWNELEKHIGRVRCRLNVVQGDAHAMPWPDASFDFVYSFSVFEHVNDPEKCLDEVIRVLRPGGVFCISTHMYTSDSGAHDPRSFLPHHGDLAPWAHLRPAHRGSVKPNAYCNAWRNEQWERLFRERCSGVVLQNIMSPDWLVPELATLRPAGELAEYSDEELLTCDLWALWQKPSR
>NZ_AP022605|552786:566944|560628_561726_+|WP_163784060.1|DBSCAN-SWA
MNRPTSFLSVKTQFENAGDALINRELVRICSRFSDVVVDTSRCPDAFLASMHLEEYSPHVKKARSASLFFTLVLQRVLRRPGYYFLIPGGYVGEKHGIQLLSLIANTAILAGMKLLGVRVCHVGVSYERLGSRHARILALRSRLMHCLLARDASSRAYAESLGIRIDGLIPDLAFGAVSYRCDISGNEGVALSFRVDQMDSQRSDAELLIRHLDEILPKSADFKFIAQVQRDAPFMHELAMRKYPSGRSSSFRATFSDADEALDAYAGCKYVLSNRLHVLLFGMIAGCEPIPCVDETVNRKVVGIFDLLGIRPVRSTDIPEGLGRSLSQAGNLGSVQISSIVASQERALHKAFSAVFCNNVSEAV
>NZ_AP022605|552786:566944|565749_566310_-|WP_099050097.1|transposase|DBSCAN-SWA
MWRSSGRIRGHGSNDNPYSESLFKTLKYGPQFPERFGSVSGARRFMNTFTNWYNHEHRHTGVVLDDRRSRADRAGIPRRQRKRRLRGHHGHRPPTPDRQQQLSIISHEARDHDTTQPETRRSNHKNTDRDPDSMSGVLGIGRPPPLPPQRLVDHLYTLNCEKPYRQTRWSHDGANHLKRSHDGVDP
>NZ_AP022605|552786:566944|556962_557409_+|WP_133055577.1|DBSCAN-SWA
MRPGNARDDAAVAELTGLLREGADGRLAGWPPDMRVLVRREKIEEGRQLSLFEQLNGYRYQLIVTNTRGGQAQRLEARHRVHAPVGGVHRLRQGHRPGPLALALVRDQHRLGHRGRPGHRPAVLDALGGRREFARFASGVRCRPLRPL
>NZ_AP022605|552786:566944|552786_554094_+|WP_085192575.1|transposase|DBSCAN-SWA
MPDATFACPDLTTFCRLDELGLQVTGQRVAPDRAFLACRITDDDSWCRRCGEQGVPRDSVTRELAHEPFGWRPTTLLVTVRRYRCAGCAHVWRQDTSKAAEPRAKLSRRAVQWALEALVCQHLSVARVAEALAVSWNTANNAVLAEGQRVLIADPARFDGVRVIGVDEHVWRHTRRGDKYVTVIIDLTPVRDGSGPARLLDMVEGRSKKAFQQWLAERPQEWRDRVEVVAMDGFSGFKTATAEELPEAATVMDPFHVVRMAGNALDECRRRVQLATCGHRGRKTDPLYACRRTLQTGADLLTDKQKARLDAVFAVDAHAEVEATWTMYQRTVAAYRHPDRKTGRTMMAALITTLSTGVPQALQEVITLGRTLKKRAADVLAYFDRPGTSNGPTEAINGRLEHLRGSALGFRNLTNYIARSLLETGGFKPQLHRHS
>NZ_AP022605|552786:566944|564679_565399_-|WP_163784064.1|transposase|DBSCAN-SWA
MYRLIEAEKAEFTVIGMTALLEVSRSGFYKWRAAQVAGPSPAQQRREVIDAKVKGFHDASDQVYGSPRILADLRDDGEVISRKTVAASMRRASRSPGSPPRQFTPVTTVVDLDAHRPKDLVDRRFDRGELDKVWTSDITYLAADEGWLFCARSATGARGGSWAGRWRITCAPIWWSPRCQWRSPCAGTYQGRSSSMPIAAPSTPPGSSPGSPALTTSPNRSAGPGCVGTTLRPNLSGAQ
>NZ_AP022605|552786:566944|565401_565698_-|WP_163784066.1|transposase|DBSCAN-SWA
MSGNRKKYTPECREQAVRLVVDTGRPIAHVAAKIGVGEQLLGRWVAAAKARLAADNPEVLDDDERAELHRLRKENAELRLDRAFLKKAAAFFASEQNR
>NZ_AP022605|552786:566944|564509_564725_-|WP_163784062.1|transposase|DBSCAN-SWA
MCWDNAQAESFWSTMKSEFYNRYTWPTKAAARLAVGDWIERVYNRRRRHSKIGMISPVEFEDRHNQTAQAA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085192575.1|552786_554094_+|transposase	ISL3 family transposase	A0A2H4PDF8	Mycobacterium_phage	1.2e-224	87.4
554672:554686	attL	NA	NA	NA	NA
WP_085192578.1|555278_556211_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_133055577.1|556962_557409_+	hypothetical protein	NA	NA	NA	NA
WP_133055578.1|557913_559314_+	lipopolysaccharide biosynthesis protein	NA	NA	NA	NA
WP_133055579.1|559492_560632_+	hypothetical protein	NA	NA	NA	NA
WP_163784060.1|560628_561726_+	polysaccharide pyruvyl transferase family protein	NA	NA	NA	NA
WP_085192581.1|561722_562715_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_163784062.1|564509_564725_-|transposase	transposase	NA	NA	NA	NA
WP_163784064.1|564679_565399_-|transposase	IS3 family transposase	NA	NA	NA	NA
WP_163784066.1|565401_565698_-|transposase	transposase	NA	NA	NA	NA
WP_099050097.1|565749_566310_-|transposase	transposase	NA	NA	NA	NA
WP_099050096.1|566209_566944_-|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
572065:572079	attR	NA	NA	NA	NA

Sequences of DBSCAN-SWA_3

Nucleotide sequences of DBSCAN-SWA_3

>NZ_AP022605|974923:1016719|DBSCAN-SWA
GATGCGCGTACCCGGTGAATCGGTGTCCGTCGCGGCCCTGCTGGCTGATCCGTCGACCTTGGTCTACGGCATCGGCAATTCCGGCCGGCAGGACGACGGGCTGGGCTGGGCCTTCGTCGATCGGCTCGAAGCCGGCCCGCACCGGTGCGCGGCGGTCCTGCACCGCGGCTACCAGCTGCACCTGGAAGACGCCGATCTGATCAACCGATTCGACACCGTGCTGTTCGTCGATGCCACCAAGGAATCCGCGGTGGCCAGTTACCGGTTGACGCGACCGGAGGCGAAGTTCGACTTCAGCTTCGCCTCGCATGCGATGTCGGTTCCGTCGGTCTTGGCGACCGCCGTACAGTGTTTCGGGTGCTGTCCCGACGCGTATCTGCTGGCGATCCGGGGCTACGAGTGGGAGTTGCGCACCGGACTGACCACCCCGGCGGCGGCCAACCTCAGCCAGTCGTTGACGTTGACGCGCCAGACCGTATCGCTTGATTAACCAGACAGTTCGCCACTTCCACGTGGTCTGCCAGCAGTGCACCGCCAGCGTCGACCTGGAGACGGTCATCGTCAGACCGGACCGGGAACGGGCTTCCCGACAGTGCCTCAACGAATTGCTGGTCGACTGCGGATGGCTGCCCACGACATGGGGCTACTACTGCCGCCAACACGCCACGGCGGTGCGCAACGGGTCGATCCGGCGCAGGTGATCCCGGCTGCCTCGGCTTGGGTCCGTTGGCCTTCCGGTTCGGGACCAATGGCACGTCGCGCGTATGGTCGGCGGAACTACGGTGAAATCATGAACCTGCGAATGAAAGCACTCGAATACTCCTACCGGATCCACTGGTCTGCCGGCCGGCACGGATACATCGCCACGGTGGCCGAATTCCCTGCGCTGCAGTCCGAACCGGCCCAGACACCGCATGCCGCGGTGGAAACGGTGATGGCCTCGGTCATCGAACGACTGCACGCGCTCGATGTCGACGGCGCTTCGATGCCGCTGCCGGGATATGGCGCCGCCGCCGACCCGCGTTCGATGCTCGACGCCTGACGATCGGTTCAGCAGATCCGTGGAAGCTGTTCGCCGATCGTGCGTTCCAGAACACGGGTGGTTCCGAACGGGGTCTTGGCCACTGCGATGCCCGCGTGGTCCTCGACCACCCGCCCGATGATCGCGGCGCCGGCGCCCTCGGGCCGGGCTTGCATCGCCTCCAGCACGGCTCCACTGTGCTTGGGATCGACGAAGGCGACCAGTTTCCCCTCGTTGGCCACGTGCAGTGGATCCAGGCCCAGGAATGAGCACGCCGACGTCACGGCCGCCGGAATCGGGATTGCGGGCTCGTCCAGCTCGACCCCCACACCGGCGGCCCTGGCGATCTCCACCACGGCGGCGACCAGACCACCGCGGGTCGGGTCGCGCAGCGCGTGCACCGCACCGGAGGCCTCGGTAACGGCCAGCATCGCCGCCACCAGGTGGTGCAGCGGGGCGCTGTCGGTGACCAGGACGGTTCCGAAGTCGATTCCCTCACGCATGCTCAGGATGGCCAGGCCATGTTCACCGATCGATCCCGACACGATGATGTGGTCGCCGGCGCGGGCCCGTTCGGGGGCGATTTCCACTCCGGCGGCCACGACGCCCACGCCGGAGGTGTTGATGAAAAGCCGGTCGGCGCTGCCTCGTTCGACGACCTTGGTATCTCCGGCGACAATGGGTGCCCCCGCGCGGGCCGCGGCCCGGCCCATGGTCTGCGCGACTGCGCCGATGACGTCGAGTTCCAGCCCCTCCTCGAGGATGAACCCTGCCGTGAGCGCCACCGGTTGGGCACCGCTGCACGCCAGATCGTTGATCGTGCCGTTGACCGCGAGATCTCCGATATTGCCGCCGGGGAAGAACAGCGGCTGCACCACATAGGAATCCGTGCTCACCGCGATCCGCCCGGCGCCGACGCTCAGCAGGGCGGAGTCCCGGGCCGGGACACCGGCCGAGCCGAACGCGGGCAGGAACAGGTTCTCGATCAGCTCCTCCGAGAGCACACCCCCGCCACCGTGCCCGAGCACGATTCGGGAGGTTTCCCGCAACGGCAGCGGGCACACCCAGTTCGCCGGGTCGACGGTCACCCGTGGCTCACACACGGACGCCGGCACCGTGCTCGAGGCGACGGAAGTGGTAGTAGGCGGCACAGGCACCCTCACTGGAGACCATCGTGGCGCCCAGTGGGGTCCGCGGACTGCAGGCGGTGCCGAACGCGGGGCACTGGTCGGGTTTGAGCAGGCCCTGCAGTACCTCCCCGCTGCGGCACTCGGCGGACTCCTCGATGGCGAGATCGCGCACCCCAAAACGGCTTTCGGCGTCGAACTCGGCGTAGCGGGGCGACAGCGTCCAACCCGAGCCCGGGATCATCCCGATACCGCGCCACTGCCGGTCGGTCACGGTGAACACCTCGGCCAGGGTGCGCTGCGCGACAGTGTTGCCCTCCGCGGTGACCGCCCGCCGATAGGCGTTGCGCAGCTCGGGGGTGCCCGATTCCAGCAGCTCGACCAGCTGGCGCACCCCTTCGAGGAGGTCGAGCGGCTCGAACCCTGTCACCACGATCGGTACCTGGAACTTCTCGACCAGCGGATCATATGCGGCGGTGCCCATGACCGAGCACACGTGCCCCGCCGCCAGGAATCCTTGCACCCGGTTGCGGGGGCCGCTGAGGATCGCGGTCATCGCCGGCGGCACCAGCACGTGCGACACCAGCATCGAGAAGTTCCTCAGCCCCGTCCGCCGGGCCTGCACCACGGCCATCGCGTTTCCCGGAGCGGTGGTTTCGAACCCGACACCGAAGAACACCACCTGGCGGTCGGGGTTGTCGGCGGCGATGCGGGTGGCGTCCAGCGGCGAGTACACGATTCGCACGTCACCGCCGCGGGCCCGCACTCCGAACAGGTCGCGGCGACTGCCGGGCACCCGCAACATGTCACCGAACGAGCAGAAGATCACGTCGTCGCGGGCGGCGATCTCCAGTGCGCGGTCGACCATCTCCAACGGCGTCACGCACACCGGGCAGCCGGGTCCGTGCACGAACTCCACCGCATCGCCCAGCAGCTGGTCGATGCCGTTGCGGATGATCGAATGCGTCTGTCCGCCGCAAACTTCCATAATGGTCCACCTGCGGGTGGCTCGCTGCTTGATGATCTCGACCAGCCGGTGTGCCGGGGCGGGGTCGTGGAACTCCTCGACGTACTTCATGACCCTTCCCTCCCGCCCGGCGGCGGCACGTCGGCGGCCCCGGCAAGCTCTTCGCCCAGCATGCCGAGTTCGGCCAGCATCGCCAGAGTTTCACGAGCGGAGGCCTCGTCCAGCCGGGTGATCGCGAACCCCGCATGCACGACCGCGTATTCCCCGATCTGGATGTCCGGTAGGTACACCAGGCACACCGTCTTGGTGGTGCCGCCGAAGTCGACGGTGGACATCAACGTCCCCGACTCCTCCCAGACGCGGACCACCCGTCCGGGTATTCCGAGACACATGTGTGACTCCGTTCGCTGTTGGCACTGCGCAGTGCGGCGGCGACGACCGCCTGACCGAGCGCGAGACCGCCGTCGTTGCAGGGCACCGCCTGATGGGTGAGAACTTCGAATCCTTGACGTGACAAAGCGTTCCGCAGGCCGTCGGTCAATAGCTGATTGACGAACACGCCGCCGGTCAGCCCGATGGTGGCGATACCGGCCGCGCGCGCGTAGGTGGCGGCCGCGTGCGCGGTAGCGCGGATCACCGCGGCGTGGAAACCGGCGGCAAGGTCGGCCGGACACACCCCCGCGCGCGACTGCTCGGCCAGACCGACGATCAGCGGAGCGGGATCGAGGACGCCGTCCGCCACGGCGAAGTCGAGCGCCGCGGCCCGCCCCGCCCCGGCCAGCCCTTCGAGTTCGACGGCGGCCTGGCCCTCGTAGGTGACCTCCTGACAGACCCCGAGCAGGCTGGCCACCGCGTCGAACAGCCGACCCATGCTGGTGGTCGGCACACAACCGACGCCGCGTCGGATCTGCTGGGCCAGGATGCGGCGGCCGTCGGCACCGACCGCCTGCACCGGCGCCAGCGCAGGGTCCCATGCGACCCCGGCACGGTGGAGCAGGTCCAGCGCGATGCGCGCGGGTTGGCGCAGCGCACCCTCGCCGCCGGGCAGGCTGAACTGCTTCACATGCCCGACGCGGGTGAAGCGGGCGGGTTCGGTGATCGCCAGCAACTCCCCACCCCAGATGGTGCCGTCAGTGCCGTAGCCGGTGCCGTCGTAGGCGACCGCCACAATCGGAGTGTCCAACCGCCCATGTTCGGCGAGCAACGCCACCGCGTGGGCGTGGTGGTGCTGCACCGGAACGGTCTCCAGCCCGCTGCGTCGGGCCCACCCGACGGTGGCGTGACGCGGATGCATGTCGCACGCGACCACCGCGGGAGGTGCGGCGGTCATGGCCGCCAGATGGTGCACCACCGATTCGAAGAGGGCCTGGGTGCGCGGGTCGGCCATATCGCCCAGGTGTGGCGACAGGTGCCCACGTCCGGCCCGGTCCAGGAGGCAGGCGACGGTCTTCACGTCACCGCCCGTGGCGAGGATCACCGCATCCGTACGCGCCGCGGTGGACACCGGAAGCGGAGCGAAGCCGCGGGAGCGCCGGACCGCGACCGTGCCGCCGTCCGGCGCGACGGTAACCACCGAGTCCTCGCACGGTAGGCGGATCGGCCGGTCGTGGCCCAGCACACCGTCCGCGATACCGGCGATCCGCGCCACGTCCTCGTCCCGGAACACCATCGGTGAGCCGCTGCCGTTGGCCGACGTCAGCACGAGGGGCACCGGACCCATGCGGGCGAAGAGCAGGTGGTGCACGGGCGAGTAAGCCAGCAGGATCCCGATGTCGCGAAGGCCGGGGGCCACTCCGTCCACGACGCCGGCGCGGCGCCGAAGGAGCACGATCGGTGCGGCCGCCGAGGTCAGTGCCCGCGCGGCAGCGGTGTCGACCTCGGCGACGACCCCCGCCGCCTCCAGGTCGGCGACCATCACCGCCAACGGCTTGGCGGGCCGCTTCTTGCGCTCTCGCAGGGTCGCCACGGCGACGTCGTGATCCGCGCGACAGGCGAGGTGGTATCCCCCGATGCCCTTCAGTGCGACGACCGAGCCGGCCAGAATGGCGGTCGCGGCGGCGCCCGGCGGATCGGCTGCGTCGCCCGGGCCCGACCACCACAGCACAGGGCCGCATTGCGGACAGGCGATGGTCTGCGCGTGGTATCGGCGGTCGTTGGGGTCCCGGTACTCGGCCGCGCAGTCCGCACACATGGGAAACCCGGCCATCGTGGTGCGGGGTCGGTCGTAGGGCAGGCCGGTGATCACGGTGTAGCGCGGCCCGCAGTTCACGCAGGTGATGAAGGGGTGTCCGTACCGGCGGTCGGCCGGGTCGAACAGCTCGCGTAGGCAGTCTGGGCAGGTCGCGAGGTCGGGCGGGATCAGGGTGGGCGGGTCGCCGGTGGCACCGGCCTCGGCTCCGGCCACGATGTGGAATCCCGGTGCGGGATGCTGCGGGGGCAGCGTCGTGAGCAGGATGGCGTCGATGTGGGCCATCGGCGGCGGCCGGGTTCTGATGGCGTCGACCGCGGCGGCCACGGCGTCGGCGTCACCCTCCAGCTCGCAGCGCACCGCCCCCTTGTCGTTGCACACGAACCCATTGACGTTATGCCGCTGCGCGATCCGCGCCACGGTGGGCCGGAAGCCGACGCCCTGCACCACTCCGGTGACGTCGACACGCACGCGCACCCGCGCATCAGGTGCGCTGACCGCCGTCATGAACCTCCGAACCACCGGGCCGTGCGCGGACATGGGCTGTCGGACACAGGTTGGTGTGCCCAGGCTAAACCCGGCAAGCGAACTCGACAATTCAAACCACGATCCGCGCCATGGTGGGACGGCGGTCGCGCGGTCACGGCCGTCGGGTGGCAGCATGGAACGGGTGCATGAGCTGTCGCTGTGTCACGCGATCGCGAACGTGGTTAGGCCGTATGTCGAAGGCCGGCGCGTCGACGTGGTGCGGGTGCAGGTAGGTGCGCTGCGGCAGGTGGTCCCGGAATCGCTCGAGTACTGTTGGTCGGTGGTCCGCACGCAGGAAGGCATGCCCGACGCCGAACTGCACCTCGACTGGGTGCCCGCCGAAGTGCACTGCCGCGGGTGTCGACGCCACAGCACCATCGAGTCCCGGTGGTCCGTTCGCTGCCCGAGCTGCGACACCGGCGAGGTCGATCTGATCTGCGGCGACGAGTTCGCCGTGATGTCGGTCGACGTCAGCGACGTCCCGGACGTCGGCGAGTTGGACTGAGGGGCACCCATGGGCAGGCTGCACCGCCACGAGGACGGCACGGTATCCGTCCACCACCACGACGGGGGACCCCGCGACCACGGCAACCATGCCGGCTACCGGACCGGCGCGCACCGGATCGAGATGCTGGAGTCGATCTTCGCCGAAAACGATGCCCTCGCTGCCCGCAACCGGGAAGCGTTCGACCTCAACGGTGTTCGTGCGGTCAACCTGATGAGTTCACCGGGCTCGGGCAAGACCACGGTACTGGCCGCGACGCTGGACCAGCTGGCCGGCGAGCTAGCCGTCGGTATCGTCGAAGGTGACATCACCACCGACCTCGACGCCGCCAAACTGGCCGGCCGGGGTGCGCAGGTCGCGCTGCTGAACACCAGTGCCGGATTCGGCGGCGAATGTCACCTCGATGCCCCGATGGTCCACCGGGCGCTGCAGGGACTCACGCTGTCGTCCCTGGAGCTGGTGATCATCGAGAACGTCGGCAACCTCGTCTGTCCGGCCGAATTCGATGTCGGTGAGCACGCCAAGGCCATGGTGTACTCCCTGACCGAGGGGGAGGACAAGCCGTTGAAGTACCCGGTGATGTTCCGGTCGGTGGACGTGGTGCTGCTCAACAAGATCGACCTGGCGCCGTATCTGGACGCCGATGTCGAGCGCTACACCGACCACGTCCGGCGGGTGAATCCGACCGCGACGATCTTCGCGGTCAGCGCCCGCACCGGCGAAGGTATGCCGGCGTGGTACGACTGGTTACGCCGGTTTGCGGCCGGTCCTCGCACCTCGGGTGCCGGGCGGGCGCTGTGAACTGCGGCCGGCCCCGTGCCACAATGCCCGCGGCGCTCCGCCCAAACGAACAAACGGGCGCGAAGTTGCGAGTAGATGGCGCCGGTTCGTCGATCTCGGCGAAAGGTCAGCGGCCGAGTTTGGCCTTGACGTCCTTGATGCTCGGGTTGGTCAGCGCCGAACCGTCCGCGAACTTCACCGTCGGAACGGTCTGGTTACCCCCGTTGACCGACATGACGAAATCCGCCGCGGCGGAGTCGCGTTCGATGTCGACTTCGGTCCATGGGATGCCCTCGACCTGCAACGCCTTCTTGAGCCGGACACAGTAGCCGCACCAACTGGTCGTGTACATGGTCAAGGTCTCAGCAGCACTCATAAGACTTCCAACGTAACCGACCGCCTCGACATGCCGACACGGACTGGGCGGTTGTCCGTGCGCCCTGCCAAGATGGGTCGCATGCCAGTCGAGGTCCCCACCTCGTCGCGGGAGCGGCTGCTTGCCGACCTCGACGAGGAACAGCGCGGGGCTGTGCTGGCGCCTCGGGGGCCGGTCTGCGTGTTGGCCGGTGCCGGCACCGGCAAGACCCGTACCATCACCCGCCGGATCGCCCACCTCGTCGCCGCGGGGCAGGTCGCACCTGGACAGGTCCTGGCCGTGACCTTCACCTCCCGCGCTGCGGGCGAGATGCGGGCCCGGCTGCGGGCCCTCGACCAGGAGGCCGGCGGTGTCGGCACCGGGTCGGTGCAGGCCATGACATTCCACGCCGCCGCCCGTCGTCAGTTGCGGTATTTCTGGCCCCGCGTCGTCGGCGACACCTCCTGGCATCTGCTCGACAGCAAGTTCCCCGTGGTGGCGCAGGCCGCCAACCGGGCGCGCGTGCAGGCCGGCACCGACGACGTCCGCGACCTCGCCGGCGAGATCGAGTGGGCGAAGGCGTCGCTGATCAGCCCGGAGGCCTACCCGGGTGCCGTCGCGCAGGCCGGGCGTGACATCCCGATGGACGCCCCGAAGGTGGCCGCCGTGTACGCCGGATACGAGGCACTCAAGGCCCGCCACGACGGCACGGCGCTCCTCGACTTCGACGATCTGCTACTCCACACCGCGGCCGCGATCGAGAACGACGCCGCGGTGGCCACGGAGTTCCGGGACCGCTACCGCTGTTTCGTCGTCGACGAATACCAGGACGTGACGCCCCTGCAGCAGCGGGTGCTCGACGCGTGGCTCGGTCCGCGCGACGATCTGACCGTCGTCGGCGACGCCAACCAGACCATCTACTCGTTCGCCGGGGCCACCCCGCGTTACCTGCTGGACTTCTCCCGCCGGTTCCCCGACGCCGCGGTGATCCGGCTCGAACGCGACTACCGCTCCACACCGCAAGTGGTGTCGCTGGCCAACCGCGTGATCGCGGCCGCGCGCGGCCGCATGGCGGGCAGCAAGCTGCACCTGGTCGGCCAGCGCCCGCCCGGCCCCGCGCCGGCCTTCGCCGAGCACTCCGACGAGGTGGCCGAGGCCGTCGCCGTGGCCAAGGACATCCGCAGGCTGCTCGACGCAGGCACCCCGGCCGCGGAGATCGCCGTGCTATACCGGATCAACGCGCAGTCGGAGGTCTACGAGGAGGCGCTCACCGAGGCCGGCATCGCGTTCCAGGTGCGCGGCGGCGAGGGGTTCTTCAGCCGTCAGGAGATCCGCCAGGCGCTCGTCACGCTGCAGCGCGCCGCTGAACGCAACCTCGAGGGGGAGGTGGCCGACGTCGTGCGCGCGCTGCTCGAACCTCTCGGGCTCACCGCAGAGCCGCCGGCGGGCACCCGGGCCAGGGAACGATGGGAAACGCTGACCGCGCTGGCCGACCTCGTCGACGAAGAGGTCGCCCTGCGTCCGGGTCTGGACATCGGCGGTCTGGTCACCGAACTGCGCCAGCGCGCTGACGCCCGGCACCCACCGGTGGTGCAGGGCGTCACGCTCGCGTCGTTGCATGCGGCCAAGGGCCTGGAGTGGGATGCGGTCTATCTCGTCGGCCTGGCCGACGGCACTCTGCCGATCTCACATGCGCTGACCCACGGCCCCGATAGTGAGCCGGTAGAGGAGGAGCGCCGGCTGTTCTATGTCGGGATAACAAGGGCTCGGGTGCATCTGACGTTGAGTTGGGCGTTGTCCCGGACGCCGGGCGGCCGCCAGAGCCGACGGCCGTCGCGGTTCCTCAACGGTGTGGCGCCGCACTCGCCGCCCGAGGCGTCGGTGACCAGGCCGCGCCGACCCCGTGGCGCCACGCCGCGCTGTCGGGTGTGCAACGAACCACTGACCACACCGCCGTCGATCATGTTGCGTCGCTGCGAAACGTGCTCGTCCGACGTCGACGAACAGCTGCTCGCGGCGCTCAAGGAATGGCGACTCAAAACGTCAAAGGAACTCGGCGTCCCGGCGTTCGTGGTGTTCACCGACAACACGCTGATCGCGATCGCCGAATCGCTGCCCACCGACGAGGCGGCGCTGGTCACCATCCCCGGAATCGGCGCCCGCAAGCTCGAGCAGTACGGCGCCGACGTTCTCGCTTTGGTCAACGCCCGCGGCTGAAACTGCCGACGACCACCAAGATCGCGCCAAAACCGCTGGCAATAAATTGGTTGTGCGATCCGGCTGTGAGGCTCTACCCTCAAGATCACACGTTTGGCGGAGACAAGGAAGGCGGGTGCCCGGATCATGGACAGCAATTTCGTGTTCACCGGCGTAGCCGTTGTCGGCAGCGTGCGTGCCGTTCGGACGGCCGCTGGGATCTCCGTTGCAGCAACGCATCCCGCCTGCACGGCAGTGGCCGGTGCACCGGCTCCGGCTGCGGCGACGCGTGTTGCCATTCCCGCGCAGCCCAAGCGCCGTGCCGCTATCGCCGCGACCCGCAGTCCGTGGAGTGGGGCTCCACCCAGGTAAGCCCCCAGCAAGCCGAATGGCCACGGACCCGCAGTCGCCGGATCCGTGGCCACAGTCTTTTTCGGGGACGCCCCTCCACGAGGACCTGGTCGCGGATTCAGCCAAAGACAGGTGGCCGAGGAAACAACGACCAGGAAGCAGGAATTTCATGTCTGTGGAGGCATGCATACAAAGCGCGGTCCCCGACTTGCCGTGCGAAGTCGGTGATCCCGACCTGTGGTTCGCCGAGAGCCCCGCCGACCTCGAACGCGCCAAGACGCTCTGCGTGAACTGCCCGATCCGCCGAGGGTGCCTGACGGCGGCATTGGAGCGTCGCGAGCCGTGGGGTGTGTGGGGTGGGGAGATCTTCGAACGCGGCACCATCGTCGCGCGTAAGCGTCCGCGGGGACGCCCGCGCAAGAACACAGCGCCGAACCCGGCGGCGGCCTAGCCCCGAGTTCCGGCCTGACGGTCAGTCCACGCCCTCGGCAAATCCCGGGATCAGTTCGGTGGCAAGGGCTTTGGCGGGGATATAGGCGTCGAGCTGGCAGGAGATCGCGACGTTCGACGCGATGACGCGCATCGGGATCGCGAGCTTGGCGGGAACGTCCATTTGGCGCACCGTCTTGATCTGTTGCACCGAGCGGTCCATGTTCACCGCCGCCATCTTCTGCAGCCACTTGCGGGTGTAGTGGAACACCTCGACCTCGAGGGGTTCGACGTACTGGCGCAGCATGTCGTCGACATCCCCGGGGGAGACCTGTTCGCCGCGCTGGATGAAGCCGATCTTCTCCAGGGTGGGCAGCAGTCGGTCGTAGTCCTTGGCCAGCGCGTACCGCACCGCCAGGCCGAGGTCGACGGGGATGCCGCCCGGCAGCGGTGCCACCGCGCCGAAGTCGATGACGCCCATCTTCCCGTCCGGCATCAGCATGAAGTTGCCGGGATGCGCGTCGCCGTGCATCATCTCCAGCCGCCGCGGCGCGTCGTAGGTCAGCTCGAACAGCCGAGTACCCATCAGGTCACGCTCTTCCTGGGTGCCGTCCCGGATGATCACCGACATCGGAATGCCGTCGATCCACTCCGCGACGACCACCTTGGGTGCGCTGGCGACGACGGCGGGTACCACGAAATGCGGGTGGTCGCGATAGGCCTGGGCGAACGCCCGCTGGTTGTCGGCTTCCAGCCGGTAGTCGAGTTCCATCTCGGTGCGCTCGACGAGTTCGTCGACCACGCCCTCGATGTCGGCGCCGGGGGAGAGCTGCTTGAGCACGCTGACCATGCGCTGCATGGTCTTCAGGTCCGCGCGCAACGCCTCGTCGGCGCCGGGGTACTGGATCTTGACCGCGACCTCGCGGCCGTCGGACCACACCGCCTTGTGCACCTGGCCGATGCTGGCCGAGGCGATCGGCTTGTCGTCGAACGAGGCGAAGCGATCCCGCCACTTGGTGCCCAGCTGCGCGTCGAGCACCCGGTGGACCTTGGCGGCGGGCAGCGGCGGGGCGTCCTTCTGCAGCTTGGTCAGGGCCTCGCGGTACGGCTTGCCGTACTGCTCAGGGATCGCGGCCTCCATCACCGAGAGGGCCTGGCCGACCTTCATCGCGCCGCCCTTGAGTTCGCCGAGCACGGTGAAGAGTTGTTGAGCCGCCTTGTCCATCAGTTCGGCGTTGACCTCGTCGCGGGACTTGCCGGTCAGCCTTTTGCCGAAGCCCAACGCCGCGCGCCCGGCCATGCCGACCGGCAGGCTCGCCAGCTTCGCGTTGCGGGCGGCGCGCCCGCGCTTGATGTCAGCCACCAGACCATCATCCACGACGCCGCCGGGCGGGCTGACGACGAACGGGTCACAACTGGTCCGTCAGCAGGTACAACGCGGATGCCGCGACCAACGTCGCACGACGGTGGTGCGGGTGCCGACGTGGAACTCCCACGTGGTGTCCGTGGCGGCGGGGTCCGCCGCGCTCACCGGGTCGCCGGTGTCCTGGATCGCCCGCAGCACCCGGTGGATGCGGTCGAGTGCGACGGCAGCGGTGGCCAACACGGTGGCCCGGTCGGCGCTGCCGACGGTGCCGCGCAGCTGGGCCGCCAGCGCCGGCCACGCCGCGTCGCGGTCACTGCGGTGCAGGTCGGCGCAGGACAGACAGCTCGTGCGGCCCGGAAACACCAGCGGTCCGATCAATCCGGAGCCGTCGCGCATCCGGACCGGTAGGTGGGCGAGGCGCGCGTTGTGCAGATCGCGCACCATGCGCGGTTCGGTCACCAGGTAGTCCGCCAGCACCACCAGGTCGGTGGACTCCGGCGGGGCGGGCGCCTTTGGGGAACGGCTGTGCCCGACCCGGGCGCCCGAACACTGCAGCCCGGCGACCAGCAGATCGGACAGCGGTCCGCGACCGTGGATGCGGATGTTCGGGGTGCGGCAGCGGCGCGGCGGGTCGGCGGTCAGCACGCCGGCGTCGACCAGGTCGCCGACGAGTTCGGCGAGGTCGGCTGGGTCGGCCGTCCCATGCTGGTGCGCTTCGCCACGCAGTTCGGCCATCGTCATCCCCGCCTGCAGGGCCCGCAGCAGATCGGCGAGCCCCGGTGCGGTGAGCCCGGCCGGTGGGCGGACCAGCGTGGCGCGGCGCGGATCCCATCCGACTTGCACCGCGCCGTCCGGGCGCAAGAGCACGGGCAGTGCCGTGTCGAGCGCGTAACGGGAAATCGCGGCGGGAGACGCGGCGAAAGACATGGAAGGACTCTGCCACGGGGCGACCGCGTCACCTGTCACCCATCGACAGGCCTGTGGATAACTAGCGCTGGTCGTCCTCGGGGCGGTCGTCCGGGCCGTCCTCGTCGGGCTTTTCCAGATCGGCTTCGAGGTCGGTGAGGGCCTGCTCGATGGCGCTGTCCACCCCGCTGGTGTCACCGCCGACGATCCGGTCGATGAACGCGGCCGGTTCGTCGAGATCGTCCGACGACGGCAACAGGTCCGGGTGCTGCCACACGCCGTCGCGGGCATCCTGGCCGGCCGCCGCGGTGAGCCGCTCCCACAGCACCGCGGCCTCGCGCAGCTTGCGCGGGCGCAGTTCGAGCCCTACCAGGGTGGCGAAGGTCTGCTCGGCAGGCCCGCCGGTGGCCCTCCGGCGGCGCAGCGTCTCCGACAGGGCGCCGGTGCCGGGAATGCGGTCGCCCAGCGCGGCGGTGACCGCGGTCTGCACCCAGCCCTCGATCAGCGCGAGCAGGGTCTCGAGCCGTTCGAGCGCCGCGACCTGCTCGGGGGTCGCCTTCGGTTCGAAGATGCCCTGGTTGAGCAGCTGTTCCAGGTGCGACGGATCGGTCAACGCGGCCGGGTTGAGGCCCTGCGCCATGTCCTCGATGCCGCTCATGTCGACCTTCATGCCGCGCGCGAACGCCTCGACCGCCGACAGCAACTGGCTCGCCAGCCAGGGCACGTGGCTGAACAACCGATGGTGGGCGGCTTCCCGCGCGGCCAGGAACGTCAACACCTCGCTGCGCGGCTGCTCGAGCCCCTCCGAGAACGCCTCGACGGCCTCAGGCAGCAGCGCGGCGACACCCTTCGGGCCGAGCGGCAGCCCGATGTCGGTCGAGGTCAGCACCTCCTTGGACAGCGTGCCCAGCGCCTGCCCGAGCTGGGAGCCGAACGCCATGCCGCCCATCTGCGACATCATCGCCAGCAGCGGCCCGGCCATCGCGCGGGCCTCCTCCGGCAGCGCCGAGGCCCACACCGTGGAGATCTGCTCGGCCACCGGGTCACATAGCCGCTTCCAGGTGTCGAGGGTGTTGTCGATCCAGTCGGTCGGCGTCCAGGCGACCGCGCGGGTGGTGCCCGCCGGCAGCGGGGTGACGCCGTCGAGCCAGGTCTCGGCGAGCCGCACCGCATCCGCGATCGCCGATGCCGTCTGTTCGGGCACGGGCGCGACGAACCCGATCGCGCTCGCCGCCAGCTGCCGGGCGAGGTCGTAGTTGACCGGTCCGGACTGGGCTCCACCGGCGGTCACAGTGCCTGCGGCGCTGAACATCTCGCCGAGTTTGGTGAAGATCTGGCCGAGGTCGGACACGTCGAAACCGGCGCCGCCCTGCCCGAACATCGAGCCGAACGGATCCGACGGCGAACCGCCCGAACGGGACCCCCCGTCGGGGTCCTTCTTGCTCTTGTCTCGCTCCGGGTCGTCACCCGAGGAGAAGCCGAAAGGCAGGTCAGCCATACCGTCAACGGTACTCACCGGCGCCAGGTCGCGCGGGGGGCCGGTCACGCTTTCGGAGAACGAGGGTGGGACTCCCTTACTGTGGGCGGCGTGAACAGGCGGATTCTGACGCTGCTGATCGCGCTGGTCCCGGTCGTGGCGTTCGGCGTGCTGCTCTCTGCGGTGACGGTCCCGTTCGTCTCGCTGGGCCCCGGACCCACCTTCGACACCCTCGGTGAGGTGGACGGGAAAGAGGTCGTCGACATCACGGGCACCGAGGTGAAGCCGACGTCCGGGCATCTGAACATGACGACGGTGTCCCAGCGCGACGGGCTGACCCTCGGACAGGCACTGACCCTGTGGATGTCGGGCCGCGAACAATTGGTGCCCCGCGAACTGGTCTACCCGCCCGACAAGAGCAAGGAGGAGATCGACGAGGCCAACACCGCCGATTTCCGCAACTCCGAGGACAACGCCGAATACGCCGCGCTGTCGTACCTGAAGTACCCGCCCGCGGTCACCGTCGAAAGCGTCACCGACCCCGGGCCGTCGGCCGGCAAGCTGAAGGACGGCGACGCGATCGACGCGGTCAACGGCAGACCGGTCGCCAATGTCGACGAGTTCCAGGCGCTGCTGAAGACGACTAAGCCCGGTGACGAGCTGGTGCTCGACTTCCGGCGTAAGGGGCAGAAGGATCCGCGCGGCAGCACCACCGTGAAACTCGGCACGAACCCCGACCGCGACTACGGATACCTGGGCATCGGCGTCATCGACGCTCCCTGGGCGTCGTTCACGATCGACTTCAACCTGGCCAACATCGGCGGGCCGTCGGCGGGGTTGATGTTCAGCCTCGCGGTGATCGACAAGCTCACCGCGGGCGACCTCAACGACGGCAAGTTCGTCGCGGGCACCGGAACCATCACCGGCGACGGCGAGGTCGGGTCGATCGGCGGCATCACCCACAAGATGCTCGCCGCCAAGGAAGCCGGCGCCTCGATCTTCCTCGTTCCCGCCGACAACTGCGCCGAAGCCAAGTCCGACCCGCAGGACGGGCTGGAGCTGGTGAAGGTCGGCACACTGACCGACGCCGTCGACGCACTCAACGTGATTTCCGCTGGTGGTGAACCACCACGGTGCTGACCGAACACGAACCCGACGATGCGTAGAGTTGGGGCACGTCGGTGACGACGTCCCCCTTTCCTGTGAGTGAAACGGAGACACCAAGTGGGTATGCGGCCCCCCGCGAGGATGCCGAAGCTGACACGACGAAGCCGGATTCTGATCGGTGTCGCCGTTGTCGCCGTGGTGCTGCTGCTGATCGGGCCGCGGTTCATCGACACCTACGTCAACTGGCTGTGGTTCGGTGAATTGGGTTACCGGTCGGTGTTCACCACGGTGCTGTTCACCCGCATCATCGTGTTCCTGGTCGTCTCCGTCCTGATCGGTGCGATCGTCTTCGCCGGCCTGGCGTTGGCGTACCGGACACGGCCTGTGTTCGTCCCGACGGTCGGACCCAACGACCCGATCGCCCGCTACCGCACCACGGTGATGTCGCGGCTGCGCCTGTTCGGCATCGGCATCCCGGCGTTCATCGGCATCCTGTCCGGCATCGTCGCGCAGACCTACTGGGTGCGGATCCAGCTGTTCCTCCACGGCGGCGAATTCGGTGTCACCGACCCGCAGTTCGGCCTCGACCTCGGCTTCTACGCCTTCGAACTGCCGTTCTACCGGCTGGTGCTGAGCTATCTGTTCGTGGCGACGTTCCTGGCCTTCATCGCGAACCTGTTAGCCCACTATCTGTTCGGTGGTATCCGGCTGACCGGGCGCAACGGGGCCCTGACCCGCTCGGCGCGGATCCAACTCGTCACCCTGGTCGGCATCTTCATCCTGCTCAAGGCGTTCGCCTACTGGCTCGACCGCTACGAATTGCTCAGCCACACCCGCGGCGGCAAGCCGTTCACCGGCGCCGGCTACACCGACATCAACGCCGTGCTGCCCGCCAAGCTGATCCTCCTGGCCATCGCGGTGATCTGCGCGGTTGCCGTGTTTTCCGCGATCGTGCTGCGCGACCTGCGGATCCCTGCCATCGGTGTGGTGCTGCTCCTGCTGTCGTCGCTGGTCGTCGGCGCCGCCTGGCCGCTGGTGGTCGAGCAGTTCAGCGTCAAGCCCAACGCCGCGCAGAAGGAAAGTGAATACATCTCGCGCAGCATCGCCGCGACGCGGCAGGCCTACGGGTTGACCGATGACGTGGTGACCTACCGGGACTACCCGGGCGACGCGCCGGCGACCGCTCAGCAGGTGGCCGCCGACCGGGCGACCACGTCGAACATCCGCGTGCTCGATCCCAACATCGTCAGCCCGGCGTTCACCCAGTTCCAGCAGGGCAAGAACTTCTACTTCTTCCCCGACCAGCTGGCGATGGACCGCTACCGCGACGACGACGGGAACCTGCGCGACTATGTGGTCGCCGCCCGTGAGCTCAACCCGGACCGGCTGATCGACAACCAGCAGGACTGGATCAACCGGCACACCGTCTACACCCACGGCAACGGGTTCATTGCGTCACCGGCCAACACCGTGCGCGGGATCGCCAACGACCCCAACCAGAACGGCGGCTACCCCGAGTTCCTCGCCAGCGTGGTGGGCGCCAACGGCAAGGTGGTCTCGCCCGGGCCGGCACCACTGGACCAGCCGCGGATCTACTTCGGCCCGGTCATCGCCAACACCGTCGACGACTACGCGATCGTCGGTGAGAACGGTGCCCCGCGCGAGTACGACTACGAGAACAACGTCGAGACCCGCAACTACACCTACACCGGATCCGGTGGTGTGGAGATCGGCAACTGGCTGACGCGGAGCCTGTTCGCGGCGAAATTCGCCGAGCGCAACTTCCTGTTCTCCAACGTCATCGGCGATGACAGCAAGATCCTGTTCAACCGCGACCCCGCTGACCGGGTGGAGGCCGCCGCGCCGTGGCTGACTACCGACACCACGGTGTACCCGGCGATCGTCAACCGCAGGATCGTGTGGATCGTCGACGGCTACACCACGCTGGACAACTACCCGTACTCGGAGTTGACGTCCTTGTCGTCGGCGACGGCGGACTCCAATGAGGTGGCCGTCAACCGGTTGGCCCTCAACAAGCAGGTGTCCTATATCCGGAACTCGGTGAAGGCCACCGTCGACGCCTACGACGGCACGGTGACGCTGTACGCGCAGGACGAGAACGACCCTGTGCTGCAGGCGTGGATGAAGGTGTTCCCGGACACGGTCAAGCCCAAGAGCGAGATCTCGCCGGAATTGCAGGATCATCTGCGCTATCCCGAGGACCTTTTCAAGGTGCAGCGCGCCCTGCTGGCGAAGTACCACGTCGACGATCCGGTGACGTTCTTCTCCACGTCGGACTTCTGGGACGTGCCGCTGGATCCGAACCCCACGGCCAGCAGCTTCCAGCCGCCGTACTACATCGTCGCCAAAGACCTTGCCGAGAACAACAGTTCAGCGGCGTTCCAGCTGACCAGTGCGATGAACCGGTTCCGCCGTGACTTCCTCGCCGCGTACATGAGCGCCAGTTCGGATCCGGAGAACTACGGGCAGATCACGGTGTTGACCATCCCGGGTCAGGTCAACGGCCCGAAGCTGGCGTTCAACGCGATCAGCACCGACACCGCGGTCAGCCAGGACCTCGGCGTGATCGGCCGGGACAACCAGAACCGGATCCGGTGGGGCAACTTGTTGACCCTGCCGGTGGGTCCTGGCGGCCTGCTTTACGTGGCGCCGGTGTACGCCTCGCCGGGCACCAGTGACGCGGCGTCGACGTACCCGCGCCTGATCCGCGTGGCGATGTTCTACAACGATCAGGTCGGGTACGGCCCGACGGTCCGTGACGCTCTCACCGACCTGTTCGGCCCAGGCGCCGACGCGACCGCCACCGGCCCGGCGCCGACCAACCTGCCCGACGGGCAGCAGCCGGCGGCCCCGCCACCGGCCGACGGTCCGCAGCCCGCGGCGCAGCCACCCGCCAACCAGACGGGCCGGGTGCCGCCGGCGCCGCCGCCTGCCGCGGTCCCGTCGGGTCCCCAGCAGTTGTCCGAGGCGAAGGCCGCGGCGCTGCAGGAGGTCCAGGAAGCGATGAGTGGACTGCAGGACGCGCAGCGCAGCGGCAACTTCGCCGAGTACGGCGAGGCGCTGCAGCGGCTGGACGACGCGATGAGCCAGTACTCCGAGACCCGCTGAGCCGACACGGGCACGTTCGCGGCCGGACAAGAGTGCCAAAGTGGTGGTAGAGGCCCGATTTGGAATACCAAGCCGGGCTGGGTAACCTCATGTTCACCAACGCGGGGTGGAGCAGCTCGGTAGCTCGCTGGGCTCATAACCCAGAGGTCGCAGGTTCGAATCCTGTCCCCGCTACCAGGTAAAACGGCCCCCGGAGACTACTCCGGGGGCCGTTTTCATGCCCGATGGGAACACTTTTGGGAACATTCCCAACGCAAAGACTTCGTGGGAACGGAATGGGAACCGACTAACCTCCCTTGGCTCACTGACGGGACGACAAGTGCGCCGCCTGGGCTGAAGCCTGTGGCGGTAGACCAACGTGACCCCGGGCGGACGTACCGCCGCGAGTCCGTCTCAGACGGCGCGAGCCGGCGGTTCGCCCTACTGTGCACGGTGCAAAATGAGCACCGTGGACGGGGATCGCTATCCCGGGAAAACTTGGGCGTGCAGATCCGCTCGCTGACAGCGAACATGGCTTATCGACGCAAGTGCTCCGCTACCGTGTGCACGCTGGCGGTCTGTAACCCATGAGGAAAGAGAGCGGGAGTGGCCCGGATAGAATCGGACGTGCTGGAAGAGTTCATAAATCGACTCGCACAGTCGGACGCCGTTCCCTCGACGGTCTCTGAAAGCCTGCGCACGCTGCTTACCCAGGAGAAGCTCCCTAAGCCCGAGCTCCTTGTGGCGCTGTATGCAACGGAAAGTGGGGATCGGCTCGCATGATCCAGCTAAAAGCCATACACATCGAAGAATTTCGGGGCATTCGGCGCCTAGATCTGAACCTGAATTGCGAATCGTTCGTCGTGGCTGGACCCAATGGCTCGGGCAAGAGTGGTGTAGTCGACGCAATTGACTTTGCGCTCACTGGCGGCATTACCCGCCTCAGCGGCTCCGGCACTGGCGGCGTCAGCCTGCTGAAGCACGGACCACACGTGCATCAGCGAGACAACCCGGCGGTAGCACGAGTTGAGCTAACGATCGTCGACACCGCTAGTGGCCAGACGGGTGTGCTGACACGTTGCATCAAGACCGCTGGACAATACACTCTGGAGCCTAGTTCGCCGGAACTTGTTGCTGCCGTGGAGTGGGCTGCTCAGCACCCTGAGCTCACGCTTTCGCGGCGGGAGGTCATTAAATACGTCAACACTGAACCGGGGAAACGAGCCCAAGAGGTTCAGGCGCTCCTCAAATTGGATCGCATCGACGACACGCGCCGACTTTTGCGTACCGCCTTGTCCAAGTCCTCAACCGACGAGAAGCAAAGCGCCGCAAAGGTGAAAGACGCCGAGGACAGCGTGCGGCGACATCTTGACTTATCTTCCTTGCTGGAGTCGGAGATACTCGGTGCGGTAAATAAGCACCGCGACGTGCTAGGCATTGAGCGACTAGGGCTGTTGACCTCTGATACTGACTTGAGCGTTGGCGCTGGAGATCCTGAAGAACCCTCCGGCTTCAATAAGGCTTCCGCGTTGCAAGATATCGCGGTCCTAATTGATTACATCGACGACCACGCTGAGTTGTCCGCAGCAGCGACCGAACTAACCTCTGAACTTGCCGAGCTAGAACGCGACCCTTCAGTGCTCGATGCGCTAAAGCACCGCGCGCTCGTTGAGGTCGGATTGCCGCTAGTCACTGATGCCGCATGCCCGCTGTGCGACCAGACCTGGGACGACGTCGAGACGTTGCGAAATCACCTCCGCGAGAAACTGGCTCGGTCTGAAGCTGCCAAATTCCTTCAGCAGCGCGTGGAGCGAGCGTCCGAGCGGGTAGCTCGGCAGGTACAGCGCGTCCAGGCTCTTATCGGGGCTGCTCAGCCACACGCCGTGAGGCTCGGACTTACGAGCGACCAAGCGACATTGTTGGAATGGTCGGCCGACTTGGCGAGCTTTAACGCGGCCCTGACCAATGTCGAGACCGCTCGTGAACAGGCAGCGCGTCTCAACTCCGACCCGCTGGGGCAGCCCCCGACGTTGATGGCTATTTTAGACGGCATTCGTGGGGCGCTCGAAGCGTTGCCTGATCAGGGCGCGACCGTTAGCGCGCGAACCGCTCTCACGATCGCTCAAGAACGATGGAACCGGCTTCGCCAAGTACGGGCCGAGCATGAAAAGGCCACTGCCGCACAACATACCGCAGATGCCGTGTACAAAACCTATAACGATGTTGCCGACTCCGCTTTGACGAATCTGTATAAGAGCGTTGAGGGCAACTTCAGTGCTTACTATCGCCAAATCAACGCTGACGACGAATCATCGTTCAAAGCCGGTTTGGCGCCGTCTGCTGGAAAGTTGGATTTAGAGGTTGATTTCTACGGTTTAGGCATGTTCCCGCCGATGGCGTATCACAGCGAAGGTCATCAGGACGGTATGGGGGTGTGCCTGTACCTAGCACTGATCAAGCAGCTATTGCGAGAAGACTTCCGCATTGCGGTGCTCGACGACGTCGTTACTTCAGTTGACACTAATCACCGTCGACAATTTTGCACCCTGCTCAAAGACGCTTTTCCTGACGTGCAGTTCATTATTACGACGCACGACGAGGTCTGGGCACGGCAGATGCAGTCGTCGGGCTTAATTCGTCGGCGTGCCCAAGCGCGATTTCACGGATGGAACGTCGACCGCGGACCCGTGTACGGCGAAGGTCAGGATTTCTGGGCACAGATCGATGCCGATCTTGCGAAAGATGATGTACCCGCGGCCGCCCACAAACTGCGCCGCAATCTGGAAGCGTCACTCGCCGATATTGCTGCTGCTATTCAGGGCAGAATCGTATATCGCCCCGACAATAACTACGATCTCGGGTCCTTCTTCTCAGCGGTCAAGGGCCGCCATGGTGATCTACTCAAAAAAGCTGCCACATCGGCGAACTCGTGGAAGAACGAGGTGGCCAAGGAGCAAGTTGAAGAGTTGAAGGCAGCCAGACAGAATGCAATGCTTGGACAAGATGGCGAAAATTGGGCGATCAACGCGTTAGTGCACAACAACGACTGGGCTGTCATGGCAAAGGCGGACTTCACGCCGGTTGTTGAGGCATGCAAGGATTTCTTGGACCTGTTTACGTGCCGCGGTTCCGAGTGCGATGCATGGGTGTACGTAGTCGGGCTACCAGGAAAGGAAGAAGCAATGCGGTGCGCATGTGGCACCCTCAACCTTAATCTGCGGTCGAAGTAAGAGCTCCATCGATCTCTCGGTTATCAGTCGCTCCTTATTCGCCGAGAATGAAACCAGCTTAGGTCGCGTCGCAAACGGATGAGCCGAGGCTCGTATGTTAGGCGTTCAGCTCGACTGTCTGGCCGCCGAAATCGGCAACAATCCGCAGGTGCCCGCCGAGTGCGGCCACGTAGGATTGCAACGTCCCCAACTCCGTGTGCGCCAGGTCGCCACTCTCGAGCTGCGACACCCGCGCCTGCGAGACGCCCATGAGCGCCGCGACGTCGGCCTGGCGAGCATGACCGTGTGCCTTGCGAATCTCGGCGAGACGATAGGCCTGGACGGCTTCGTGCATCTTCTTGCGTGCCGAGTCCGCGCGTGCCGGGTCGACGCGACCTTGTTCCACCGCCTCGGCCCGGATCTCACGCCAGTTGCGCGCCATGCCTACTCACCTCCGTGGCCGGTCGCCAGCCATCTGGCGTAACGCTCGTCGGCGACCGGGATGTTCTTGTCGTACCAGCTTCTCCAGTTCCCGGCCTTGTCTCCGCCGAGCAGCAGAATCGCCTGGCGTTGCGGATCGAAGATGAACAGGATGCGGACGCTCGTACCGGCGGGACGCAGCTCCTTCATGTTGTGGAACTTCGACCCGTTTACCCGGTCCACCGTCGGCCGGCCCAAGGCGGGCCCCTCCGCCTCGAGTAGGTCGATGGCGCCAGTCACCGACGTCATCGTGTCGTCGTCCAGCGTGAAGTACCACCGTTCGACCTCCTCCAGCAGGAGTACCGCCCACGCCATCAGTATAACTCCAGCATTATATCGGTCAGACTCCGTCAGTCGAGGTCCGTCGGGTCGGCGTCCTCGTCGTCGGCCCACGCGTCACCGATCAGGAACCCGGCCGCCTGCTCGGCGGCCTCCCGGTCGTCGTTCTCCAGCACGTGGGCGTACGTCTCGAGGAAGAAGCCGACGTTGGCGTGGCCGATGCGTTCGCTGATGACCTTCGGATTGACCCCTGCCCGCAGGGCGCCGGTGGCGTACGAGTGGCGCAGGTCGTGAAAGGTGATGCGGGACAGGCCCGCCGCGGCCGACAGACGGTCGAAGCGCTGCCGGATCGAGTCTGGGTGCAACGGCCGGCCGTCTTCGTAGGTGAACACGTAGCCGCCGGGGTGATAGTCCGGCCCGAAGAACGCCCGCTCGCCGTCCTGGACCTCACGCCAGCGGCGCAGTGCAGCCACGGTGGCGCGGTCGATCGAGATGGTTTTGTCGGCATTGCGGGTCTTGCCTCCCGCTTTGTCGCGGGCCTGCCCGCCGACGACCACGCGGTTGTCGTGGACCGCGATGTGGCCGGCGTCGAGGTCGACGGCCGACCACCGCAGCCCGCAGATCTGGCCGCGCCGGATACCCGTGGTGAGCTCCAGCAGGAAGAGCGCGCCGAAGCGGTCATGCCGGACGGACGCGAGGAAGGTCTGGATCTCTTCCGGCTTCCACACCTGGCGGCGGGTGCGCGGCCGTCGTGGCGGCTTCACATTGCTTGCGGGGTTGTCGGTGAGGAACTTCCACGCGACCGCGTCGACCAAGGCGCGATGCAGGAACGCATGTACGTTGCGGACCGTCTTGGGTGCGAGACCGCGGGGCGTCGGTTCCGGCACGATGCCGGAGCGGTATCGGCGCACCGCGGCGCGGGCGGCGTGAATCGAGGTGCCGCAGGCCTCGGACACCGCACGCGGTGTGGGCTCGGCTCCGCGCGCGGCGCGCTTCGACCAGTACGCGTACATCACCGAGTCGTTGTCGCGTTTGACGCGTCCCTCGGCGAGCAGCTTCGCGTAGAGCTTCAGCAGGGTGGGTTCGTCGAGTCGTTGGAGGCGCTCGCCGCCGATGTGCGGAATGACGTACCACCGCGCGTAATCGCTCCAACTGCGCCAGGTGGTGGCGTCGAGTGTCGGTTCGACCGCGGTGAGCCACTCGGTGAGGAACTCGCCGACGGTGCGGGTGGAGGGTTTGACGATGCGGCCGCGGTCCGCGTCGCGCATCGCGTCACGGCAGGCCTTCCACGCCTCCCGCTCGGTGTCGAAGCCGCCCTTGGTGATCCATGGGTAGGTGCCGGTGGCGGGATCACGTTGTGGGGAGCGGAATTTGTAGTACCACTTCGCGCCCCGGTGATACACCGATCCCTTCATGACGCGAGCTCACGGAGACCTGAGGTCACGACATAGACGCGGCCGCCCAGCCGGCGAACCGGCAACTCGCCGGAGTTCACGAGGCGATACGCCGCTGCTCGGCTGATCCCCAGCAGTTCCGCGGCGTGCGGCACGGAGAGAAGCAGGGGGAGTCCCTTGAACGGGTTGTCTTCCATTTTGATCACCACCCTCCACTGGAGTTGTGTGGGGCTACGGCTCGTGCGACGTGCTGCAGCGCGTGTGTGGAATTTGTCGCCGCGACGTCACGTCGCAGACGGTTCTGCTTGGCTGCGCTGAGGTTCATCAGGCACCCAACACCACTGTAATTCGCGGCACGACAGGTTTGTGCAGAGTTTTCGCGCATCGACTCACGACGAGTCACGCAATGCGCAATGTCGCAATGCTTTTCACACCCCCGGACTTACTACACACTATCCTCCCCTTCCCGCCATCGCCTCACTTTCCGTCAATCGCATCACCATGCATACCGCTGCGTCTCCAAACACGCTGCCTCCCTTACTCTTATCCCAGGCGCTTCACCTCGTCTCACATCCCCGACACCCCCAAAGTTCTGCATGGCACATTTGCACAACGGTGCGAGAATGGCTGTGGCGCAGCACGTGCCGCGGGCGCCAGCGGGAGGGGCGAGACGATGTTGACGATCGCCAAGTTGAAGCGGTGGTCGATCAACTACTACATCGACACCGCCCAGGCGGCCGAGCGCGCGTCCAAAGATCGCGCCCGGTCCGGCGGTGGGCTGGGGGAGTACTACTCCGAACACGAGACCCGCACTCCGGTGTGGTTGTGCGCGGGTGACACCCGCCGCGCGGCGGCTTTGGTCGGGTTGACAGACGCCCAGCGCGCGGGCGGGGAGGCTGACGCGGGGGTGGTGGCGCGCTGGCTCGATGACGGGGTCGCCCCGAGCGGTGCGCGTGGTCGGGCGTTCGGGGAGCGCGGGGTGCATGGCTTCGATCTGACGTTCTGCGCGCCGAAGAGTGTGTCGTTGGTGCGGGCGTTGCGCGTCGACGACGTCGTGATGAAGGCGATGGCCGATGCGCATGACACCGCGTTACGTGAGGCGATGGAGTATGTGTCGACGCACGCGGGGTACACGCGGGTGCACAACCCACGGACCGGTGAGAAGGATCTGGTGCGGCTGCCCGGTTTGGTGGCGGTGGCCTATCAGCATGAGACGTCGCGGTGCGGGGATCCGCATCTGCATACCCACGTCATCGTCCCCAACCGGCAGGCCCGCGTCGACGGACAGCTGGTGTCGATCGACGGCACATCGCTGTATCACGAAGCGCGGGCCGCCGGAGTGATCTATCAAGCCACGCTGCGCCGGGAACTGCACCGGTCCATGGTGTTCGAGTGGGCGCCGGTCGATTCATCGACCGGCATGGCCGAGCTGGCTGGAGTGGACCGCGACACAATCACCGCGTGGTCGCGACGATCGACCGCGTTGCGGGAGTGGGCCGCCGGCAATCTCAAGGTGGTCGATGGGCCCTTGTCGGCGGCGCAGCTTGCCGCCGCGCAGAAAGCCACCCGCCCCGGCAAGCCCGAAGAATTGGCCTGGGGACAGCTGGTCGCGGAATGGCGCGCCGATGCGCGGGGTCTGCGCCTGGACCGCGCAGCGTTCGAGGCGGCGCGCGCGGCGCGGCGCGCGGCCGCGCGGACGCCGTTCGACCGTGCGCGCCTGGCCGCGGCCGCGGAGAAGATCGAGAAGGCGGCGTTCACCCGCGCGGACCTGGTCGAGATCGTCGGCGCGCACCTTCCCGTCGACAGCGACCAGTCACCGCGGGAACTGGTGGAGGCTGCGGTCGACGAAGTGGGGGTCAGGCTGACCGCCCCGCGGGCGGCGCATCAGCGGGAGGGACATGAGCGGTTCACCCTCGATCAAATCCTCAATGAAGAGAAAGCGGTACTGTGAACCGTCCCCGGTTTTGTGCGCACTTCCTTTGTTGGGAAGGATGGCGCGATGCCGAGTAAGTACGACGAGAACACCAAGGCCAGGGCGGTGCGGTTGGTCCGCGAGCACCGCGATGATTACGACTCGGAGTGGGCGGCGATGAAGGCGATCGCGGGCCGGCTGGGGATGAACGCGGAGACGCTGCGCAAGTGGGTTCGCCAGGCCGAGGTCGACGCCGGTGAGGCGGCAGGGATGTCCAGCGAGGAGAGCCGGGAGCTGCGGGAGCTACGCCGCAAGACCAGGGAGCTTGAGGCCACGATCGAAATCCTCAAGGCCGCAACGACTTTCTTCGCGCGGGAGTGCGACCCGCTACACCGCTGATCTGTGCGTTCATCGACGAACACAAGGAGCGGTTCGGGGTCGTACCGATCTGCCGCGCCCTGGGGATCCAGGGCGTGGCGATCGCCCCGCGCACCTACTGGGCACACCGCTCGTCGGCACCATCAAAACGGGCCCTGTGGGACACCACGATCACCGAGATCCTGGCCGGCTACTACGAACCCGACGCCGACGGGAAACACCCACCAGAGAGCCTGTACGGCAGCCTGAAGATGTGGGCGCACCTGCAACGTCAGGGCATCCCGGTGGCGCGGCGCACGGTGGAACGGATCATGCGCCACAACGGCTGGCGGGGCGTCATGCGTGCTCGCCGCCCGCCGCGCACCACCGAGCGCGACCCGGCCGCGGACCGGGCGCCGGACCTGGTGGGCCGCAACTGGCGCGTTGGCGCACCCAATTTGCTGGAGGTAGCTGACTTCACCTACGTCCCGCTGGACACCGGTGGGTTCGGCTACACCGCGTTCGTCGTCGACGCCTATGCCGGGCTGATCCCAGGCTGGGAGTGCTCGATGGTCAAAGACACCGGATTCGTCGAGCGCGCGCTGCGCCACGCGGCAATCTTCCGGGCCCGTCAAGGCCATCCATTCAACGACACGATCCATCATAGCGACGCCGGAAGCCAGTACACCGCAATCCATTACAGCGAAACGCTGATGTTGGAGGGGCTGATCCCCTCGATCGGTACCGTCGGCGATGCCCTGGACAACGCGCTGTGCGAAACTACGATCGGGCTCTACAAGACCGAGTGCGTTCGCCCTGGCTCCCCGTTTCGTACGGGGCCGATCCGAACCGTCGCCGACCTGGAGAACATGACCTCGGGGTGGGTTAGCTGGTACAACGAGCGCAGGCTCATGCACCGCCTGGGCCGCATCCCACCGGCCGAGGTCGAGGCCGAGTACTACGCTCGACTCCAGGCCGGAGAGCACACCGGTCACACGTAACGAGGTGTGCATGAAACCGGGGATGCTTCACTGGATCTGGTCGATGCGCAGGAGCCGCGCGCCATGCTGTGGATCAAGCCCGAAGACACCGCCGGACTCTCGGCCGATCAGCGCCGCGCCGTGGAGAACATCGGCGCATCGCCATGGTTGGTGCAGCCGTTGTCCGCGCCGGCGGGTGCGGGCAAGACCACCACCATGCGCGCCTTGATGCCGGCGGTGCACCGCCGCCACTACGGCCACATCCTGGTCCTCGCCCCGACAGGCAAGGCGGTCGATGTCGCGATGCGGGAGGGGGCCGGCGACACCGGCCACACCGTCGCCAAAGCCCTCCAACTGCTGCGCGACAACCAACTCGATCTGAGCCCGGCGACATTGGTCGTCGTCGACGAGGCCGCCATGGTCGGCACCAACGATCTCCGTCAACTCCTCACCGCGACGACTGCCGCCGGGGCGAAGACAGTCCTAGCGGGAGTTTCCGGGCTACGGTGAGGGATGGTTTGATTGTGCCTGGTGGCGCGGTGTTTTCGGGCAGTGGTGGTGTATTACCCAACGTGTCGTGGGGCGCTGTGGGTGGGTCAGCGGGTGGGCGCGTATTGGTGAAGTTGAACAGGTCGGCTAGTTTTCGCTGGGTGGGGGTCATGTCGGTGAGCATGCGTTGGGCGCGGGGGCGGCCCTTGGCGCCGTCGTGGTAGAGCAGCACGGTTTCTTCGATGCCGGCGAGTTGGTCGAGTAGTTCACGCACTGACAGGTGCAGGCCGGCCTGGTCGGCGTGGCGGCGCATCAGGTGGGCGACGGCCAGGGCGAGCACGCAGTAGAACACGTGCACGCGGATCTTGGAGTCGGTCCAGTGGTGCATCGGGCTGAACGAGACCACGTGGGGGTCTTTGAGTTGGCGGAAGCCGAACTCGGCGTCGGATTGGGACCGGTAGGCGGCCACCACATCGGGCACCGGCCAGTCGCGGTTGGTGAACAGGATCCGTTTTCCGAACAGCCGCGCCTCGAGCCGGGCCCGGGCGCGGGGGTCGGTGCGCCAGGTCAGACGCAGTTCGGCGGGCCCGTCGCCGGTCAGCGTGACGGTGAGGATGTCGGCGACCCAGCGGGGCTTGCAGATGGCGGCGATCTCGGCCTCCACCTTGTCGCGGTCACGGCGGGTGCGGCCGCGGGCCAGCCTGGCGGCCAGCTCGGCCAGGCGGCGCCGCGCCTTGGCCAGGGTCTGGTCCAGGCCGCGGGCCTGCTTGGCGTGCAGGTTCGCCGAATGGGTGAGCACCGCGCGGCGGGTCACCCCGAGCGCGGTGACGGTGGTGTCGACGTAGCTCAGTCCCGGGTAGCGGTCGGGGTCCACCGGTCGGAAGGAGCGGTCGGGGATCGCCAGCAGGTCGGGGTGATCGCTGGGCGGCAGTGAGCCGACGAACCCGATGCCATGCTCTTCCACCACGGTGTGGTTGTCGCTGCTGTTCTGCCCGGCGTCATAGACCACGGTCAGCGACTCCACCCCGGCGACCAGGTCCGCATAGCGGGTCACCAATTCGTCGATGACCGCGCTGAACTGGGTGACGTCGGGCCGGTCTCCGGGGTAGGCATGGCTGATCACCGGCACCCCGCCGTCGCGGGTGATGACCAGCGCCAACCCGACCAGCCGCAGATCGGTGCGTTTCTGCTTGGCCTTGCCCCGCTGCGCGATCGGCGCGCGCTGGTTGCCGGTGTCGATGAAGGTGGCGAAGTTGGTTATGTCCAGCGCCAGCCCGCTCAGGTCCAGCCCGAACTCGGTCACCATCGCCCGCGACAGCCGGCTCTCGATCTGCCGCAGCTGCACCTCGTCGAGGCGGTCCATCGCATCCCAGAACCGGCGGTGATCGGTCGCGGCCCGGTTCAGTTTCACCCACCGGCCCCCGGCTGTCGTGTCCCACCAGTCGGCGAAGCCGCGCTTGGAGCACGGATCAACAATCCGGTTCGCACACGCCAACGCCACATAGGTGCCCACCGACGCGGCCGCATCCCCGCGGCGGGGCGCCACTTCATCGACGATGCCGGCCACGTCCAGCCGGACCAGCATCGACCACACTGCCGCCAAGTCGCCGAACCGCTTGTGCTGGCTGCGGACCGGCTGCCCGCCCGGCGTCTGCGTCAGCTTGGCCAGCACCTCCTCGGCGCTGCCCAGATACTGCTGGGACACGATGCGTGGCTTGCCGCCCACCCGGGCGGACTCCACCAGGTAGTAGTAGGTCTGCTGCCCGCGGCGCTTCCCCACGATCGACGCCATATATGGGTAATACACTCCTGTCACACAAACCTCAAGCACCACAACACAAGACACGCCGGTCAACTACAGAGCCCGGAAACTCCCGCTAGTGGGCGATGAGCATCAGCTGGCCCCGGTCAAAGCTCGTGGCGGCATGTTCGCCCAACTCTGCGACGACCTGCCCTGGACGCAGAAACTGTCCGAGGTGTGGCGGATGCGCGACCCCGAGGAACGCACCGCCTCACTTGCGTTGCGCGACGGAAACCCGGCCGAGGTGGCCCGCGCCGTCTCTTGGTATCGCACTCATGACCGGCTGCACTGCGGTGACGCCGTCACCATGGCCCAAGACGCACTCGCCGCCTACCAGACTGACCTGTCGAAAGGCCATGACGCGCTGTTGATCTGCGACACCACCGAAATGGCCCGCGCGCTCAATTGGCGCCTCCATGGACAACGCATCGGTAGAGACGAGCCCACCCTGACCGTCGCGAATGGAGAGCAGGTCGGGGTGGGGGATCTGATCGTCAGCCGCCGCAACGATCCCGACGTCACGGTCATCGACAATCCACAAGCCACCGAGTCCGCCCCGATGGTCCGCAACGGAAACCGCTGGCGAGTCGCCGCAGTCGACGAGAGGAACGATCGCATCGCCGCGGTGCGGCTCGATGACGGCGTCGGTGCCGTTTTCAGAGGGGACTACGTGCGCGAGCACATCAACCTCGGATACGCCGTCACCGTGCACTCCGCCCAAGGCGTCACCGCCGACACCAGCCACGCCATCCTCGGCGAAAACAGCACCCGAAACCTGCTCTACGTAGCCATGACTCGCGGCCGCCACACCAACACCGCACACCTCTACGAACGCACCGTGGAGAACCTTCCTTCGCTGGAGTCTGTACCACTTGCCCGCGGAAACTCCACCGAAGCGGCGCAACTCGTGCGGTCCCTGACTGCCCGCGACGACACGCCGCAGACTGCCCATCAAATCGCCTCCCAGGCGAATCTCGCAGCGATGCCCGCAATCGTCGCGGGGTTCGTGAGCTGCCGCACCGACGCGATCGAATCTCGACGAGAGGCCTTCGGCAGTTGGAAGGCCGCGATCGCTCAACAAAACCAGGGACAGGATTTGGCGCGCGACCGAGGCATCAGCCTGAGCCGAGGTAGTGACAACGGTCTGGATCTCTAAGCTCACCAAGGTCGCGACGAGCTACACAAACTGTGCTATCGCGATCCCTTTACCACCAAGCATCAACTTGACACACATCACCATCGAGGATTGCCGGAATCATATGAAAACCAGAAGTATTCGCGAACTCATCGATTCGCACAGTCTGCTTCGTGATTGCCCCCGTGGGCATGACTAGCACCACAATCGGTATCAGTGAGGTTTTCTCACTTGGGGCGTGTGAGGTTGGTGTGACTGGAGTTTCCGGCGTGTCGTGAGAGCAGGACGTGGGGTCCCTGCTCAAGGATCGGTTCCGACGAAGAAAGCCGTTCCGCTGCAAGAGGACCCCACGTGTTCACCTACTCTGCCATCTGCGACGTCCCCGAGGAAACCCTGCTTCATGTGACCGCGTTGCTGCACGCGCACCGGCGCGAGATCGGCACCCGCGCCGGGCGTCGCGCGGGCACAGCCCGCACGCAGGCCAAGCTGGTGCTGCGCTGGTTCCGCGACGACGCCCCGATCCGGCTGCTGGCCTTCGAGGCCGAGCTGCCAATCTCCACCTCCTACCGGTACCTGCACGAGGCGATCGACGTGATCGCCGAACAAACACCCGAGCTGCACGACGTGCTCGACCGGGCGAAGCGGGAACAGTGGTCGCATCTGACGCTGGACGGCACGCTGATCGAGATCGACCGGGTGAACGAGCGCGCCGAGGCCGGTCATCACCTGTGGTACTCGGGCAAGCACAAGACTCAGGGCGGCAACGTGCAGATCCTCGCCGACCCGGGCGGGTTCCCGGTGTGGTCGAGCGAGGTCGAACCGGGCAGCGTGCACGACATCACCGCTGCCCGCGCGCACTGTCTGGGCGCGTTGTACAAGGCAGCCGCCGACGGCGTGCCGACGCTGACGGACAAGGGATACGAGGGCGCCGGGATCGGGGTGCACAGCCCGGTCAAAGGCCGCGACCTCGATGTCGCCAATCGCAGCTACAACACGCTGCTGACCGCGACCCGGGCAATCGGGGAACGCGCCAATGCCGAACTCAAAGAACGCTGGCGGTGTCTCCGGCGAATCAGACTGTGCCCAACCAGAATCGGCCAGATTGTTGCCGCCGCAATCGTCCTATCAACTCTCCAGAGGGGAAACTACTGAGAAAACGTCAGTCCACGTTATCCGCACCGAATGTGTTGGCCGCGCACATTTTGTCGACGCGCGAGCTTCGGTGCAAATTGACCTCAGCTCAACAGATTTCTACGAGTCGCCTCGGTGGCACTCCGTGATGAAGCATAGGCGAATTGCGGGGCGCATCGGTGCACGCGGCGATCCCTGGTTCTGTCTGGCCAATGGAGTAGATCTACCTACCGCATAGGATGCCGGCGAGCCAGCGTTTCGATCTCATCGGTGGTGATGTGCGCGCGCTTGCTCACGGTCGGCGGCGTCGCGAAATCTGCTGGGCCGCCTTCGACGTTGAAGCACTCCACAATGGCGACCAGGTTGGAGTCCATCAGCTCGGCCCAACCCTCATTGCGAGACGGGTGATGCCAGGAGTGGCATACAGCGGGTAGCCCAGAAACAAGATCGGTGAACGGGTGAATCTCGCCCGGATGTAACTCCGTCCAGCAGCTGACGTCAACCCAGGCGTCATCTACGAGCGTGGTATTACTCTTATGGACCAGCTCCCAGGCGAGAGGCGGAAAGTAGACCGATGCAATAGCATTAATTCCGCGCGGCACGCCGGCAAGATTTCGACGCACGTAAGGCCCGGTAACGTGAAACCCGGCGATGGGACCCGCGACGCGGGCTGTTTTGCCGCGAGCCAACGCCAGATATATACCGATGCTCGACGGCATTTGAAAAGGGCCGCCGCTCAGGAGCCCCTCCGCAAGACTCGTCCACTGGCGTTGAATCGAAGGCCCCGTTGCACACATACCGATGAGGATCGAGCGAGCTACCGCGCCTGGATCGATCAAAACTGGCGGCATTGCGATAAGGCGGGGTACCTCGATATTCCAGTTCTTGATCCATACAACGCGTAGATCATTTGCAAACTGGCCGTATGCCGGCTCTTCGATTTTAATGGGGCAGTTGTGATTTCGCTCTCGTAGGGCGTGTCGCTGCGTGGGGAGGCCCTTGGCCTTCGGAAGTCTGAAAGTTGCGAAGCATTCAGGCTGACGAAGGGAACCAAGGGCCGTGTCCGACGGTACGACATTGTTGTTTGGGCTGCCAGGAGTGAGGGTTGAGCGTGTCGAGCGCTGGGCCGACGGGACACGGGTAGTACACGCGGTGACCGCGAGCGAGTCGGCGGCGGCGTGCCCGTCGTGTGGGGTGTTGTCCACCTCGGTGAAGGCCCGAGTCGCCACCGCGCCGAAGGATATCCCGTACGGTGAGGAACGAATCATGCTGCAGTGGAACAAGACCCGCTGGCGTTGCCGGGAGGACTACTGCGAACGTGGATCCTTTACCGAGTCCATCGCGCAGGTGCCGGCGCGGGCTCGCACGACCCTGCGGTTGCGCACTCAGGTCGGCGCGGCGATTGGGGATGCGGCCCGTTCTGTGGCCGAGGTCGCAGACAGCCACGGCGTGTCGTGGCCGACCGCGCACCGCGCGTTCGTCGCACACGCCGAGTCGCTGCTGGTTGAGCCACAGCCAGCCGCGGTGCTGGGCATCGATGAGACCCGTCGCGGAAAGCCCAGGTGGGAACGCTGCGCCGCGACGCAGCGGTGGACGCGGGTGGACCCGTGGGACACCGGGTTCGTCGACCTGGCCGGCGATCAGGGCCTGCTCGGTCAGCGAGAAGGCCGCAGCAGCGCCACCGTGATCGACTGGCTGCGCGAACGCAGCGAGGAGTTCCGGGCCGGGGTGCAGTTCGTGGCCATCGACCCGGCCGCGGTCTACGCGACGGCGATCCCGCACCCCGGACCTGCTGCCGAACGCGACGATCGTGGTCGATCACTTCCATCTGGTGAAGCTCGGCAACGACGCGGTCACCAGGTGCGCCGCCGCGTAACCTGGGACCTCCGTGATCGTCGCGGCCGTAAACTCGATCCCGAATGGGCGAACCGCCGACGGCTGCTGCGCGCACGGGAATGTCTGTCAGACAAGAGTTTCGCGAAGATGTGGAATGCGATCGTCGCCGAGGACGACAGCGCACAGATCCTCTCAGCGTGGATCGCCAAGGAAGAGCTGCGCACCGTGCTGTCCACCGTGCGGGTCGGCGGCGACCCGCATCTGACGCGGCACCGCCTGCACCGGTTCCTGTCCTGGTGCATCGATTCGCAAATCCCGGAACTGCTGACCCTGGCCGCCACCGTGGACACCTGGTGCCCGAGATCAACGCCTTCATCCAAACCGGAATCACCAACGCCGGCACCGAGGGATACAACCGGCTCGTCAAGCAGGTCAAGCGCGTCGGCTGCGGCTTCCGGAATCGAGACAACTCGGCCCGCCGGATACGATTCCACTGCACCCGCAAACAGCGGGCCGCAACCCAGACATCATGCTGATTGCCCGCTCAAAATCGAAGAGCCCGTATGCCGCATCGTAAGCGCTCGCTTTGCCGTTGCAATCACTGCAATGCCCGTAGAAATGCATTCCGCACATTGCATTACGGCCAGCATCCACCTCGTGCCCGCTAACCCGCAGAGAGAACCGGTTCACGAGCATTTCGTTGCCGGCGCACCGTGGAGGTACGTGGGCCTTCGTCATTCGGCGCTTGTCGCCGCACATACCGCAGGTGAAGAGTCAACGTCAATTTCGTAGTGGACCGAGGACTCGTTTGGCACTCACGTTGGACACGCCCGCAAGGGGAGGGCTCGCGTCCGACAATGCAATGCTTGTCAGCGACGAGCTGCTGCGACATTTACCCATAACTTATCTATGGCTCCGCGTCCGCCATCCCGCTGAACCCCTTGCATGGGCCCAAGCAGCCGTCGCAATGAAGATAACCTTGCTCGGCTCCCCATTTCAAAATCTCGTAGCGACGAGAATTGCTAAGATCCAGCGTGAGCTCGGTGAAACGCGCCTGTGGATATCTAGGACGGGCAACCATTGAGACTTCGTGAGCCATTACGTTACGCGCGTTTCCGTACGCGAGTATTGGATACGTGGAGCCGATTCGGTGCTCGCAATCCTTGGATTTGCAAACAGTGCAATCCCCTGCGCTGTCCCGTTCGGCAACCTTGTCATACGTAAGCCCCGTGGTGTGGTCGCACTCATCCACGAGACGGTCGCATACTGAACACTCGAATTCGCTTGTCAGGCCCGCGGACATACCTATACGGATGTGCGACATCCGAATTGAACAACTAGTCCAAAAATCACCGTCGCGAAATGTGATTGGGCAGCCGAAAAGCCCTCGTCGAACGAAAGCCGCTCGATGGATTGCCTCGTGTGCGGTTTCGCTCAGATTGTGATCCTCGAGGAAATTCAGAGCGGCAACAGCTGATTTCTCAGACTTGCGGATTCGCGGTTCAATCTCCTGCAAAAGATCTGGGCTAAGCGTCGTGGTGAATTCGTCCCACTGCGCGCGGAGACGGCTCTGAATACGCAGGCGTGCATCGTCATCGTCCTCCATGAGAGGCATGTGCATGACGGGCACTGAGCCCCGCTGTGCGTCAAGCATCTGCATAACAGCGGCGAATTTATCGTCGGCCACCTGCAAAGCCCGGCGACCATTCACATCAAGATAGCGGACCCGACTCGGGCCGCCCGCGGGTGGAACTGGCCCCCACTGAACTACCGTCGCCTTGAACTGCAGGCCCTTATTCTTCAAGGTCATCCGTGAGTCGGCGTTGATCACCTTTTGATAGCAGATTAAGCGCGTCCATAACGTCCGCGCCGCTGCCCTCAAGTTCGTAGGTTTCCGAAATTCCCGCGTTCATATCCAGCTTGGCGATGGAGACTTTCAAGGGCAGCGCCTCTGCTTCGCTCGTCGTCCAGCCTTGAGACTGTCGACGTATTTCAATGAAGTGCTGAATCGTGGGGATCAACCAGTCGCTTGCGAGACTCACGACGGCGACAGCGAGTGCCCAAACTTCGACAGCACTGAACTCCTGCAAGTATCTCCGCGAATTTGCAGGGGTCGAAAACTCTACGGCGGCGCCCCCAGCGCGGGCCACCTTAGGCAAGTAACGAACGTTGTCGGTATACAACGGAAAACGTTCGTCAGTGTCCTCAGCCGAAGTGCGCGTCGGTAGTACGTAGACCGTTTCTGCCTCGACCTGCGCGGGCAAGGCCCCAGCGAGCGGTATCCAGATACCCCGCGTGACGCGCGCTGACATGGGACACGTATAGCTTTGTAAGCCCCACAAGGGGCAGCGCGGTCGGTCAAGCCTCGGGCAGGTCTCGATATTGCAGTCCTCGAAGCTTTTGCGAAGGCCCCGAGCGGTCTAACGAGTTCGTCCAAATCGGTGCGCCAACTGGTGGGAGGAAAGCTATTTGATCCTGCGCTTCCGGCAACGAGGCGAACACGCCGATACGGACCCATTTTGCTGATGCTTCGATGGAGAGACAGTCGAAAATGCCCGGTTTTAGCTGTGACTTGTCGTCCCCGGTCCCGATCCAACCAGCGGCGTTTATTTTCGAGCAGATGCCCCTGTTTATGTAACCGGTCCCGTATACGCATTCTATTCCTGCAGGGGGGGCGATCGTGGGACCGCTGCCTAGGTCACACAGATTTTTCCTTGTGGAGGATCACGTCCGCCTTGCTTGCGTCAGTGAATGGGGCACCGGGCAAATGTTCGGGTGCGGTCGACTTGTTGGTGACGTACGGATCGCGCCAGAGAAAATGAGTGGCGGCTAACCCCTGGCACATGTGACCATCGAGGGATGACCTCTAGGACAAAACGCCGTGAAACACGGCGCCGTAGACGAGCAAAGGCAGAGGCGACAAGCCCGGGCATCGACCGCCACGGTGCAGTAATGATGACTGTGATAGCGGAGTCCGCGGCCTTGCTGCAGCAGGCACCTGGTGGCGAAGCCACCCTCCCGTGGCTGGAACAGCAACTGGCAGACACCATCGACTCGCTATCTGCTGGGCTCAGCCGGTACACCACATTCGCTGTTTGCGAGGTGTCCCGGCTTAACTTGTTGCCGTGGACCTTCATGCAGGGCGTCAATTTCATGGACACGGATGGTGGTCCCGCGCGGCTCGAATTGCTGACCTTGCTCGCCGCTGCGACCTCGCAGAGGCACAACGGTGATGCGCTACCAATATGGAAACAGTTCGCTGAGTGGAAGACGGCGGCGGACAAGATAATTCAGCTGTCGGCGATGATCAACCTCTACCGCGCAATCGAAGACGGCGCGCTTGATCCCATGGCTAAGATCCAGGCCAGCACCCGCGCGAGCGAAGTGTTGCTTCGCGAATCATCGTATGGGGACATGGTAAAGGCGACACTGACGGATCTGTTTGATCCGCCCCAAATTAAATCTGCTCTGGTAGATCTTCTGTCCTTCGACCTCGGCGGTGCAATTAGTGTGCTGGAGGCGTGCGACGAGATTCAGACCGACAAGCTCAATGAGCGACTTGCTGCGATGAGAGCTGCGCTCGATCAGGGCATGGCGAACGAAGAGAATCTGACTGACGCTGACAAAGAAGAAATAGGAAACAGGGTGAACATCACCTGGGACCCGTCAGACGACGACGTGTCCGCGAGTGTTGCTGAGATAGCGGAACGACTCCGAATTCCTGAAAGTACGGTTGCCGCGGTACTTGCCCAGTTCGTTCTACCGAGCGATCTTGGGTCGCCTGAAGAAGTAGTTTCGAGCTTTACTACCGGCGACAACGCTCTGCGGACAAACCCCGTCATCTCTGACGGGAACGGCCGCTTCTTGCTGGTTCATCCCTCTTTGGTCCTCCCCGCGATCCGCGAGAATCTAGAGCAGCGCCTGAAGCAGTCGCCGTTCTGGAACGAATACCAAGCACACCGCGGCAAATACCTCGAATATGAGACGTCCAAATGCCTTAGTCAAGTGCTACCGGGTGCGGACGTTCGTTCAGGCTTCGAATACTTCATCCCGGCTGACGAGACCGAGGCCGCGGGCGATCCGGCTGGCTACACAAAGTTGGTCGAGGGTGACCTCCTCTATCTGCTGGATGATGTCGCGGTCGTCGCTGAGGAAAAGGCGGTAGCGCTCGCTCCTAGTGCACGAGCTGGCAACACTCGACGCCTGCGCAATGACTTGGTTCGCATCGTGACAAGAGCGGCGGAGCAGGCTGGCCGGCTGAAAGAACGAATGGAGAAGGACAGGGGATTTCGTCTCCGAGACGGCACCTGGGTAAACACCGAGAACGTTCGTGAAATCCACACCATGGCAGTGAGTCTGGAAGATCTGTCTGGAGTGAGCACCGCGACGGCTGACATGCTTCGAGCGGGTCTGTTAGACGCCGAGAGTATTCCATGGACGGTCTCGTTAAATGATCTGAGGCTCATAGTCGAGCTGGTGGACCCATCCGCAGTCGCAGTATTTCTGCTGTACTTGCGGCGCCGTCGGCACCCAGAGGCCACGGTAGTGTTCGCTGCGGTGGACGAGCTTGACTTCTTCCTCAATTTTTTCGAAAATGGTTTGTACGTTCAGCCGGATCCCGAGCTCATGAGAGCCGAACTGCCATATATGACCGGAACGCAGACTGGCTACCGGAGGCGAAGGGATGGGCAAGCTCGCCAATTCATCACCAGCAGAACGGATCCGCTCGACGCTTGGCACGCCTATACATCTGGCTATTCGGATGTACCCGCTAGAAAGCCCGAGATTAGGAATTCGCCGACGATCCCGCTGCTTCGGGAGTTGCAGACCCGTAGGGACTTCGGTTGGTGCAGTATCGGCGCTACTTTGTTGTCGGGATCTACCCGGACGCAGCAGGAGTGGATGAACACTCCGAAGGATCTGATCAAGCGAGCCAGGTTCGACGGTCATGGGCACTCCGTAACACGGCCCTACGGATCGAACCGCGCGGATGCGTGGGTTCAGGTGTGGGCCGTCGAAGACTCGTCGACGCCCGAATTTGGGGCGGCGATCGCCAATCTGAAGGACTACATCCGAGCGAAGAAGTATCAACTACGTTTTCCGCGCGCGATGGCGCTACTTTTCGACTCGCAATCGGGGCAGCTGCACACCGCCCTCTACGATGGGACTCCCTTAGTTGCAGACGAATACTTGGATGGTTTGGTCGCAAAACTATTCCCGGCTGATAAATGGCAGAAATCGCTTCCAAAGCTTCCTAATACACGGCGTGGCAAACGGCGATAGGTGTGGGGAATACCCGGCCGGCATCCTCGGTTAGCGTCGCACTGCCGAGAAGCGTTTGCGGTAACGGCAAGCTGCGGGATACGGCCACGTCGCCCATGCGGTATTTATTGGCACGCGGCTTCGAAACTGACGCGGCGTGGGGGCGGCGCACGGTTCAGGGGCAAGGGCATCGGTCGCGGGCAGGATTGGCATGGCATCGAGTCAGACGGGAATCTTCACCGGCAATCGCCGGTATCCCGTCTCGCACGCAACTCCGTCGTCACCGTCGCGGTCGAGCTTCCTGGAGTAGCCGGGTTGTCCGGCAAATAAGCGGCAAGGCGCTAGCGGCACGCGCGCGGTTCCCAACTGCTGTCGGCGTGTGCCGCCGGTGCCACACCAAATTGGAGTCCGGCGATCACGGCAGCAATACCGAAAGCTGCGAAAAGTGCAGACCTGACCATGTATCCCCCCGACGTCTGGCAGCCGAACGCGCGAATGCGACCGGGCCGCGGTCAAGATCACTGGGCAATCACCAGACGCGAGCTGACAGGCAAGCGGACGTTCTTGCCCGCCGGTGATGAGCAGCTTGGAGGTCGAGAGCAGACTGCCCCGTGTGGTCGAGTGCCGCCAGGACCTCGCGTACCACTGTGCGCGGCCCACCATCGACGCCGAGGCGAGTCGCATCCCACCAGGCCACTCCGACGCCTTGATCGCTCGGCCGGGGCGAGGCCGTGGGCGTCGTGACCGTTGTTGACCGTCTCTGGGGGTGACGACCACGGGGTGTTGTGCCGTCGTTGATCGTGCCGATGTGGTGGCCGGCGTTGGGGTGGGTTTGATCTTGGTGGTCTGCACCGTCAGTGTGTCGATGAACTGATGGGTGCACGGCGCCGCCGCTGATTTCTTGGCCGAACCTTCGGCGACGCCGTGCGTAGTGCGAAAGGCACTGATGGTCACGGTAGAGGTCGATTCCGAGCGCGTCGAGTCCCGGTTGGCTGCTGGGGAGGTGTCGTGCCCGTCATGCCCGGACGGGGTGTTGGTGCGGTGGGGTTTCGCCCGTTCTCGCCAGGTGGTTGGGTCGGCCGCGCCGGTGCGGCCGCGGCGGTCTCGGTGCCGCACGTGTTTGGTGACCCATGTGTTGCTGCCGGTGACGTTGCTGCTGCGCAGGGCCTATGTCGCGGAGCTGATCTGGGCGGCGGTGGTGGCGAAGGCGGCCGGTGGGGGGCACCGCCGGATCGGGGCGCGGTTGGGGATTCCCGGATCGACGGTCCGCGGCTGGCTGCGAGTGATCACCGGGCGCGCGCAGGTGGTGCGGCACTGGTTCCTCTCGGTCGCGGTCGCTGCGGGGGTAGACGTGTCGATACCGAGGTCGACCGGGTCGGGGTGCGGGGACGTTGTCGCCGCGGTCGGCGCTGCGCGGGCCGCGGTCGGGGCGCGTTTCGGTGAGCGGTCGGTGATCGGTGCGGTGACGTCGGCGCGGGTGGCTGCTGCGTGCAGCGGTGGCCGGCTGCTGTCACCGGGTTGGCCGCCGGCACCGAAACCGGTCGGTGCAACACCAGTTGACCCTGACATCAGCGGTGTGGATGGGTCATCGTCGCGAGGATGACTGCCCGGCAAACGGTTGGGTGGCATCACCGAGACAGGAGTGGGTGTCATCAGTACCGAGGACGAGAAGCGCCGCCAGAGAAGTCACGCCGTGGGGTTGTTCCGCTACCAGTTGATCTGCCCGGCATTGGACAAGGATTTGTCGACGAAGGCTCGTGGCCGGCTGGTCCGTGAGATCGCCGCCCGTGAGCACACCGACCCGTTCGGGACGTCGGTGCGCTACTCGCGCGACACCTTGGACCGCTGGATCCGCCGCTACCGCGCTGGCGGGTTCGTCGAGTTGATCCCCTCATCGCGATCGTCGGCGCCGCGCACCGACGGCGCCACGTTGGAGTTGGCGGCCTCGCTCAAGCGGGAGAATCCGGCGCGGACCGCCGCGCAGGTGGGGCGCATCCTGCGGGCGGCCACGGGGTGGTCACCGTCTGAGTCGACGCTGCTGCGGCTGTTTCACCGCCTCGAGTTGATCGGCCCGGCCGCCGGGGACGTCCCGGCGGTGTTCGGCCGGTTCGAGGCCGAGAACCCCAATGATCGGTGGACCGGGGATGCGTTGCATGGCCCGAAGATTGGTGGCCGCAAGACCTATCTGTTCGCTTTCTTGGACGATCATTCCCGGCTGGTCTGCGGCTATCGGTTCGGCTTCAGCGAGGACACCGTCCGGTTGGGCGTCGCTCTGGAACCGGCGTTGGCCGCTCGTGGAGTTTCGGCCAGTGTCTACGTCGACAACGGGTCGGCGTTCGTTGATGCCTGGTTGTTGCGGGCGTGCGCGAAACTGGGGATCCGGCTGGTGCATTCCACCCCGCACCGTCCCCAAGGCCGCGGGAAGATCGAACGGTTCTTCCGGACCGTGCGTGAGCAGTTCCTCGTGGAGGTCGTCGACACGACTGCCGACGAGCTGGCCGCCGCCGGCACTGATCACCGCACCGCGCTGTGGGAACTCAACCGGTTGCTGACCGCGTGGATCGAAACCGAGTACCACCGCCGGATTCACACCGAGACCGGGCAAGCCCCGCTGGACCGCTGGGATGCGGGGTGGCAGCGGCTGGGGCGGACTCCGGCGATGCCGACCTCCGATGATCTGACCGAGGCGTTCCTGTGGTCGGAGTACCGCATGGTCACCAAGACCGCGACAGTGTCATTGCATGGCAACACCTTCCAAGTCGACGCGGCGCTGGTAGGCCGCAAGGTCGAGTTGGTGTTCTCACCGTTCGACATGGAGACCGTGGAAGTTCGATACCGGAACATGAGTCATGGGAAGGCGTTGCCGCACAACATCACCCGCCACGTTCATCCGAAGGCCCGACCCGAGACGCCCGATCCGGCGGTGGTGCCCGCGACGGGGATCGACTACCTCGAGCTGACCGAGCGAACCCATCATCAGCAGGTCCGCGCCGACCGGCGGATCGGTTACGACGCCCTCTTCGGCGATGGCCAAGACCCAAGCGGCGACGAGGGTCAGATTCACGGGGAACTCAGCCTCCACGACGTAGACGACATCGAGCGGAACGGAACAACTGCATGA

Protein sequences of DBSCAN-SWA_3

>NZ_AP022605|974923:1016719|985109_985391_+|WP_085190024.1|DBSCAN-SWA
MSVEACIQSAVPDLPCEVGDPDLWFAESPADLERAKTLCVNCPIRRGCLTAALERREPWGVWGGEIFERGTIVARKRPRGRPRKNTAPNPAAA
>NZ_AP022605|974923:1016719|990342_993354_+|WP_085190019.1|DBSCAN-SWA
MGMRPPARMPKLTRRSRILIGVAVVAVVLLLIGPRFIDTYVNWLWFGELGYRSVFTTVLFTRIIVFLVVSVLIGAIVFAGLALAYRTRPVFVPTVGPNDPIARYRTTVMSRLRLFGIGIPAFIGILSGIVAQTYWVRIQLFLHGGEFGVTDPQFGLDLGFYAFELPFYRLVLSYLFVATFLAFIANLLAHYLFGGIRLTGRNGALTRSARIQLVTLVGIFILLKAFAYWLDRYELLSHTRGGKPFTGAGYTDINAVLPAKLILLAIAVICAVAVFSAIVLRDLRIPAIGVVLLLLSSLVVGAAWPLVVEQFSVKPNAAQKESEYISRSIAATRQAYGLTDDVVTYRDYPGDAPATAQQVAADRATTSNIRVLDPNIVSPAFTQFQQGKNFYFFPDQLAMDRYRDDDGNLRDYVVAARELNPDRLIDNQQDWINRHTVYTHGNGFIASPANTVRGIANDPNQNGGYPEFLASVVGANGKVVSPGPAPLDQPRIYFGPVIANTVDDYAIVGENGAPREYDYENNVETRNYTYTGSGGVEIGNWLTRSLFAAKFAERNFLFSNVIGDDSKILFNRDPADRVEAAAPWLTTDTTVYPAIVNRRIVWIVDGYTTLDNYPYSELTSLSSATADSNEVAVNRLALNKQVSYIRNSVKATVDAYDGTVTLYAQDENDPVLQAWMKVFPDTVKPKSEISPELQDHLRYPEDLFKVQRALLAKYHVDDPVTFFSTSDFWDVPLDPNPTASSFQPPYYIVAKDLAENNSSAAFQLTSAMNRFRRDFLAAYMSASSDPENYGQITVLTIPGQVNGPKLAFNAISTDTAVSQDLGVIGRDNQNRIRWGNLLTLPVGPGGLLYVAPVYASPGTSDAASTYPRLIRVAMFYNDQVGYGPTVRDALTDLFGPGADATATGPAPTNLPDGQQPAAPPPADGPQPAAQPPANQTGRVPPAPPPAAVPSGPQQLSEAKAAALQEVQEAMSGLQDAQRSGNFAEYGEALQRLDDAMSQYSETR
>NZ_AP022605|974923:1016719|996660_996984_-|WP_085190015.1|DBSCAN-SWA
MARNWREIRAEAVEQGRVDPARADSARKKMHEAVQAYRLAEIRKAHGHARQADVAALMGVSQARVSQLESGDLAHTELGTLQSYVAALGGHLRIVADFGGQTVELNA
>NZ_AP022605|974923:1016719|1015249_1016719_+|WP_085191704.1|integrase,transposase|DBSCAN-SWA
MSTEDEKRRQRSHAVGLFRYQLICPALDKDLSTKARGRLVREIAAREHTDPFGTSVRYSRDTLDRWIRRYRAGGFVELIPSSRSSAPRTDGATLELAASLKRENPARTAAQVGRILRAATGWSPSESTLLRLFHRLELIGPAAGDVPAVFGRFEAENPNDRWTGDALHGPKIGGRKTYLFAFLDDHSRLVCGYRFGFSEDTVRLGVALEPALAARGVSASVYVDNGSAFVDAWLLRACAKLGIRLVHSTPHRPQGRGKIERFFRTVREQFLVEVVDTTADELAAAGTDHRTALWELNRLLTAWIETEYHRRIHTETGQAPLDRWDAGWQRLGRTPAMPTSDDLTEAFLWSEYRMVTKTATVSLHGNTFQVDAALVGRKVELVFSPFDMETVEVRYRNMSHGKALPHNITRHVHPKARPETPDPAVVPATGIDYLELTERTHHQQVRADRRIGYDALFGDGQDPSGDEGQIHGELSLHDVDDIERNGTTA
>NZ_AP022605|974923:1016719|1000694_1001964_+|WP_099050197.1|transposase|DBSCAN-SWA
MPSKYDENTKARAVRLVREHRDDYDSEWAAMKAIAGRLGMNAETLRKWVRQAEVDAGEAAGMSSEESRELRELRRKTRELEATIEILKAATTFFRAGVRPATPLICAFIDEHKERFGVVPICRALGIQGVAIAPRTYWAHRSSAPSKRALWDTTITEILAGYYEPDADGKHPPESLYGSLKMWAHLQRQGIPVARRTVERIMRHNGWRGVMRARRPPRTTERDPAADRAPDLVGRNWRVGAPNLLEVADFTYVPLDTGGFGYTAFVVDAYAGLIPGWECSMVKDTGFVERALRHAAIFRARQGHPFNDTIHHSDAGSQYTAIHYSETLMLEGLIPSIGTVGDALDNALCETTIGLYKTECVRPGSPFRTGPIRTVADLENMTSGWVSWYNERRLMHRLGRIPPAEVEAEYYARLQAGEHTGHT
>NZ_AP022605|974923:1016719|981267_982059_+|WP_085190030.1|DBSCAN-SWA
MGRLHRHEDGTVSVHHHDGGPRDHGNHAGYRTGAHRIEMLESIFAENDALAARNREAFDLNGVRAVNLMSSPGSGKTTVLAATLDQLAGELAVGIVEGDITTDLDAAKLAGRGAQVALLNTSAGFGGECHLDAPMVHRALQGLTLSSLELVIIENVGNLVCPAEFDVGEHAKAMVYSLTEGEDKPLKYPVMFRSVDVVLLNKIDLAPYLDADVERYTDHVRRVNPTATIFAVSARTGEGMPAWYDWLRRFAAGPRTSGAGRAL
>NZ_AP022605|974923:1016719|1011288_1013619_+|WP_085191698.1|DBSCAN-SWA
MMTVIAESAALLQQAPGGEATLPWLEQQLADTIDSLSAGLSRYTTFAVCEVSRLNLLPWTFMQGVNFMDTDGGPARLELLTLLAAATSQRHNGDALPIWKQFAEWKTAADKIIQLSAMINLYRAIEDGALDPMAKIQASTRASEVLLRESSYGDMVKATLTDLFDPPQIKSALVDLLSFDLGGAISVLEACDEIQTDKLNERLAAMRAALDQGMANEENLTDADKEEIGNRVNITWDPSDDDVSASVAEIAERLRIPESTVAAVLAQFVLPSDLGSPEEVVSSFTTGDNALRTNPVISDGNGRFLLVHPSLVLPAIRENLEQRLKQSPFWNEYQAHRGKYLEYETSKCLSQVLPGADVRSGFEYFIPADETEAAGDPAGYTKLVEGDLLYLLDDVAVVAEEKAVALAPSARAGNTRRLRNDLVRIVTRAAEQAGRLKERMEKDRGFRLRDGTWVNTENVREIHTMAVSLEDLSGVSTATADMLRAGLLDAESIPWTVSLNDLRLIVELVDPSAVAVFLLYLRRRRHPEATVVFAAVDELDFFLNFFENGLYVQPDPELMRAELPYMTGTQTGYRRRRDGQARQFITSRTDPLDAWHAYTSGYSDVPARKPEIRNSPTIPLLRELQTRRDFGWCSIGATLLSGSTRTQQEWMNTPKDLIKRARFDGHGHSVTRPYGSNRADAWVQVWAVEDSSTPEFGAAIANLKDYIRAKKYQLRFPRAMALLFDSQSGQLHTALYDGTPLVADEYLDGLVAKLFPADKWQKSLPKLPNTRRGKRR
>NZ_AP022605|974923:1016719|985412_986747_-|WP_085190023.1|DBSCAN-SWA
MDDGLVADIKRGRAARNAKLASLPVGMAGRAALGFGKRLTGKSRDEVNAELMDKAAQQLFTVLGELKGGAMKVGQALSVMEAAIPEQYGKPYREALTKLQKDAPPLPAAKVHRVLDAQLGTKWRDRFASFDDKPIASASIGQVHKAVWSDGREVAVKIQYPGADEALRADLKTMQRMVSVLKQLSPGADIEGVVDELVERTEMELDYRLEADNQRAFAQAYRDHPHFVVPAVVASAPKVVVAEWIDGIPMSVIIRDGTQEERDLMGTRLFELTYDAPRRLEMMHGDAHPGNFMLMPDGKMGVIDFGAVAPLPGGIPVDLGLAVRYALAKDYDRLLPTLEKIGFIQRGEQVSPGDVDDMLRQYVEPLEVEVFHYTRKWLQKMAAVNMDRSVQQIKTVRQMDVPAKLAIPMRVIASNVAISCQLDAYIPAKALATELIPGFAEGVD
>NZ_AP022605|974923:1016719|997372_998716_-|WP_109749304.1|integrase|DBSCAN-SWA
MKGSVYHRGAKWYYKFRSPQRDPATGTYPWITKGGFDTEREAWKACRDAMRDADRGRIVKPSTRTVGEFLTEWLTAVEPTLDATTWRSWSDYARWYVIPHIGGERLQRLDEPTLLKLYAKLLAEGRVKRDNDSVMYAYWSKRAARGAEPTPRAVSEACGTSIHAARAAVRRYRSGIVPEPTPRGLAPKTVRNVHAFLHRALVDAVAWKFLTDNPASNVKPPRRPRTRRQVWKPEEIQTFLASVRHDRFGALFLLELTTGIRRGQICGLRWSAVDLDAGHIAVHDNRVVVGGQARDKAGGKTRNADKTISIDRATVAALRRWREVQDGERAFFGPDYHPGGYVFTYEDGRPLHPDSIRQRFDRLSAAAGLSRITFHDLRHSYATGALRAGVNPKVISERIGHANVGFFLETYAHVLENDDREAAEQAAGFLIGDAWADDEDADPTDLD
>NZ_AP022605|974923:1016719|989229_990258_+|WP_085190280.1|DBSCAN-SWA
MNRRILTLLIALVPVVAFGVLLSAVTVPFVSLGPGPTFDTLGEVDGKEVVDITGTEVKPTSGHLNMTTVSQRDGLTLGQALTLWMSGREQLVPRELVYPPDKSKEEIDEANTADFRNSEDNAEYAALSYLKYPPAVTVESVTDPGPSAGKLKDGDAIDAVNGRPVANVDEFQALLKTTKPGDELVLDFRRKGQKDPRGSTTVKLGTNPDRDYGYLGIGVIDAPWASFTIDFNLANIGGPSAGLMFSLAVIDKLTAGDLNDGKFVAGTGTITGDGEVGSIGGITHKMLAAKEAGASIFLVPADNCAEAKSDPQDGLELVKVGTLTDAVDALNVISAGGEPPRC
>NZ_AP022605|974923:1016719|977038_978148_-|WP_085190034.1|DBSCAN-SWA
MKYVEEFHDPAPAHRLVEIIKQRATRRWTIMEVCGGQTHSIIRNGIDQLLGDAVEFVHGPGCPVCVTPLEMVDRALEIAARDDVIFCSFGDMLRVPGSRRDLFGVRARGGDVRIVYSPLDATRIAADNPDRQVVFFGVGFETTAPGNAMAVVQARRTGLRNFSMLVSHVLVPPAMTAILSGPRNRVQGFLAAGHVCSVMGTAAYDPLVEKFQVPIVVTGFEPLDLLEGVRQLVELLESGTPELRNAYRRAVTAEGNTVAQRTLAEVFTVTDRQWRGIGMIPGSGWTLSPRYAEFDAESRFGVRDLAIEESAECRSGEVLQGLLKPDQCPAFGTACSPRTPLGATMVSSEGACAAYYHFRRLEHGAGVRV
>NZ_AP022605|974923:1016719|975972_977046_-|WP_085190288.1|DBSCAN-SWA
MCEPRVTVDPANWVCPLPLRETSRIVLGHGGGGVLSEELIENLFLPAFGSAGVPARDSALLSVGAGRIAVSTDSYVVQPLFFPGGNIGDLAVNGTINDLACSGAQPVALTAGFILEEGLELDVIGAVAQTMGRAAARAGAPIVAGDTKVVERGSADRLFINTSGVGVVAAGVEIAPERARAGDHIIVSGSIGEHGLAILSMREGIDFGTVLVTDSAPLHHLVAAMLAVTEASGAVHALRDPTRGGLVAAVVEIARAAGVGVELDEPAIPIPAAVTSACSFLGLDPLHVANEGKLVAFVDPKHSGAVLEAMQARPEGAGAAIIGRVVEDHAGIAVAKTPFGTTRVLERTIGEQLPRIC
>NZ_AP022605|974923:1016719|986792_987635_-|WP_085190283.1|DBSCAN-SWA
MSRYALDTALPVLLRPDGAVQVGWDPRRATLVRPPAGLTAPGLADLLRALQAGMTMAELRGEAHQHGTADPADLAELVGDLVDAGVLTADPPRRCRTPNIRIHGRGPLSDLLVAGLQCSGARVGHSRSPKAPAPPESTDLVVLADYLVTEPRMVRDLHNARLAHLPVRMRDGSGLIGPLVFPGRTSCLSCADLHRSDRDAAWPALAAQLRGTVGSADRATVLATAAVALDRIHRVLRAIQDTGDPVSAADPAATDTTWEFHVGTRTTVVRRWSRHPRCTC
>NZ_AP022605|974923:1016719|1002028_1002454_+|WP_085190276.1|DBSCAN-SWA
MLWIKPEDTAGLSADQRRAVENIGASPWLVQPLSAPAGAGKTTTMRALMPAVHRRHYGHILVLAPTGKAVDVAMREGAGDTGHTVAKALQLLRDNQLDLSPATLVVVDEAAMVGTNDLRQLLTATTAAGAKTVLAGVSGLR
>NZ_AP022605|974923:1016719|975712_975964_+|WP_085190035.1|DBSCAN-SWA
MNLRMKALEYSYRIHWSAGRHGYIATVAEFPALQSEPAQTPHAAVETVMASVIERLHALDVDGASMPLPGYGAAADPRSMLDA
>NZ_AP022605|974923:1016719|978144_978429_-|WP_085190032.1|DBSCAN-SWA
MCLGIPGRVVRVWEESGTLMSTVDFGGTTKTVCLVYLPDIQIGEYAVVHAGFAITRLDEASARETLAMLAELGMLGEELAGAADVPPPGGREGS
>NZ_AP022605|974923:1016719|987723_989139_-|WP_085190021.1|protease|DBSCAN-SWA
MADLPFGFSSGDDPERDKSKKDPDGGSRSGGSPSDPFGSMFGQGGAGFDVSDLGQIFTKLGEMFSAAGTVTAGGAQSGPVNYDLARQLAASAIGFVAPVPEQTASAIADAVRLAETWLDGVTPLPAGTTRAVAWTPTDWIDNTLDTWKRLCDPVAEQISTVWASALPEEARAMAGPLLAMMSQMGGMAFGSQLGQALGTLSKEVLTSTDIGLPLGPKGVAALLPEAVEAFSEGLEQPRSEVLTFLAAREAAHHRLFSHVPWLASQLLSAVEAFARGMKVDMSGIEDMAQGLNPAALTDPSHLEQLLNQGIFEPKATPEQVAALERLETLLALIEGWVQTAVTAALGDRIPGTGALSETLRRRRATGGPAEQTFATLVGLELRPRKLREAAVLWERLTAAAGQDARDGVWQHPDLLPSSDDLDEPAAFIDRIVGGDTSGVDSAIEQALTDLEADLEKPDEDGPDDRPEDDQR
>NZ_AP022605|974923:1016719|996986_997337_-|WP_085190014.1|DBSCAN-SWA
MAWAVLLLEEVERWYFTLDDDTMTSVTGAIDLLEAEGPALGRPTVDRVNGSKFHNMKELRPAGTSVRILFIFDPQRQAILLLGGDKAGNWRSWYDKNIPVADERYARWLATGHGGE
>NZ_AP022605|974923:1016719|974923_975412_+|WP_085190039.1|protease|DBSCAN-SWA
MRVPGESVSVAALLADPSTLVYGIGNSGRQDDGLGWAFVDRLEAGPHRCAAVLHRGYQLHLEDADLINRFDTVLFVDATKESAVASYRLTRPEAKFDFSFASHAMSVPSVLATAVQCFGCCPDAYLLAIRGYEWELRTGLTTPAAANLSQSLTLTRQTVSLD
>NZ_AP022605|974923:1016719|1005720_1006521_+|WP_085190010.1|transposase|DBSCAN-SWA
MFTYSAICDVPEETLLHVTALLHAHRREIGTRAGRRAGTARTQAKLVLRWFRDDAPIRLLAFEAELPISTSYRYLHEAIDVIAEQTPELHDVLDRAKREQWSHLTLDGTLIEIDRVNERAEAGHHLWYSGKHKTQGGNVQILADPGGFPVWSSEVEPGSVHDITAARAHCLGALYKAAADGVPTLTDKGYEGAGIGVHSPVKGRDLDVANRSYNTLLTATRAIGERANAELKERWRCLRRIRLCPTRIGQIVAAAIVLSTLQRGNY
>NZ_AP022605|974923:1016719|982486_984610_+|WP_085190026.1|DBSCAN-SWA
MGRMPVEVPTSSRERLLADLDEEQRGAVLAPRGPVCVLAGAGTGKTRTITRRIAHLVAAGQVAPGQVLAVTFTSRAAGEMRARLRALDQEAGGVGTGSVQAMTFHAAARRQLRYFWPRVVGDTSWHLLDSKFPVVAQAANRARVQAGTDDVRDLAGEIEWAKASLISPEAYPGAVAQAGRDIPMDAPKVAAVYAGYEALKARHDGTALLDFDDLLLHTAAAIENDAAVATEFRDRYRCFVVDEYQDVTPLQQRVLDAWLGPRDDLTVVGDANQTIYSFAGATPRYLLDFSRRFPDAAVIRLERDYRSTPQVVSLANRVIAAARGRMAGSKLHLVGQRPPGPAPAFAEHSDEVAEAVAVAKDIRRLLDAGTPAAEIAVLYRINAQSEVYEEALTEAGIAFQVRGGEGFFSRQEIRQALVTLQRAAERNLEGEVADVVRALLEPLGLTAEPPAGTRARERWETLTALADLVDEEVALRPGLDIGGLVTELRQRADARHPPVVQGVTLASLHAAKGLEWDAVYLVGLADGTLPISHALTHGPDSEPVEEERRLFYVGITRARVHLTLSWALSRTPGGRQSRRPSRFLNGVAPHSPPEASVTRPRRPRGATPRCRVCNEPLTTPPSIMLRRCETCSSDVDEQLLAALKEWRLKTSKELGVPAFVVFTDNTLIAIAESLPTDEAALVTIPGIGARKLEQYGADVLALVNARG
>NZ_AP022605|974923:1016719|1004313_1005390_+|WP_085190012.1|DBSCAN-SWA
MGDEHQLAPVKARGGMFAQLCDDLPWTQKLSEVWRMRDPEERTASLALRDGNPAEVARAVSWYRTHDRLHCGDAVTMAQDALAAYQTDLSKGHDALLICDTTEMARALNWRLHGQRIGRDEPTLTVANGEQVGVGDLIVSRRNDPDVTVIDNPQATESAPMVRNGNRWRVAAVDERNDRIAAVRLDDGVGAVFRGDYVREHINLGYAVTVHSAQGVTADTSHAILGENSTRNLLYVAMTRGRHTNTAHLYERTVENLPSLESVPLARGNSTEAAQLVRSLTARDDTPQTAHQIASQANLAAMPAIVAGFVSCRTDAIESRREAFGSWKAAIAQQNQGQDLARDRGISLSRGSDNGLDL
>NZ_AP022605|974923:1016719|978371_980732_-|WP_085190286.1|DBSCAN-SWA
MTAVSAPDARVRVRVDVTGVVQGVGFRPTVARIAQRHNVNGFVCNDKGAVRCELEGDADAVAAAVDAIRTRPPPMAHIDAILLTTLPPQHPAPGFHIVAGAEAGATGDPPTLIPPDLATCPDCLRELFDPADRRYGHPFITCVNCGPRYTVITGLPYDRPRTTMAGFPMCADCAAEYRDPNDRRYHAQTIACPQCGPVLWWSGPGDAADPPGAAATAILAGSVVALKGIGGYHLACRADHDVAVATLRERKKRPAKPLAVMVADLEAAGVVAEVDTAAARALTSAAAPIVLLRRRAGVVDGVAPGLRDIGILLAYSPVHHLLFARMGPVPLVLTSANGSGSPMVFRDEDVARIAGIADGVLGHDRPIRLPCEDSVVTVAPDGGTVAVRRSRGFAPLPVSTAARTDAVILATGGDVKTVACLLDRAGRGHLSPHLGDMADPRTQALFESVVHHLAAMTAAPPAVVACDMHPRHATVGWARRSGLETVPVQHHHAHAVALLAEHGRLDTPIVAVAYDGTGYGTDGTIWGGELLAITEPARFTRVGHVKQFSLPGGEGALRQPARIALDLLHRAGVAWDPALAPVQAVGADGRRILAQQIRRGVGCVPTTSMGRLFDAVASLLGVCQEVTYEGQAAVELEGLAGAGRAAALDFAVADGVLDPAPLIVGLAEQSRAGVCPADLAAGFHAAVIRATAHAAATYARAAGIATIGLTGGVFVNQLLTDGLRNALSRQGFEVLTHQAVPCNDGGLALGQAVVAAALRSANSERSHTCVSEYPDGWSASGRSRGR
>NZ_AP022605|974923:1016719|980895_981258_+|WP_085190285.1|DBSCAN-SWA
MHELSLCHAIANVVRPYVEGRRVDVVRVQVGALRQVVPESLEYCWSVVRTQEGMPDAELHLDWVPAEVHCRGCRRHSTIESRWSVRCPSCDTGEVDLICGDEFAVMSVDVSDVPDVGELD
>NZ_AP022605|974923:1016719|975404_975623_+|WP_133055529.1|DBSCAN-SWA
MINQTVRHFHVVCQQCTASVDLETVIVRPDRERASRQCLNELLVDCGWLPTTWGYYCRQHATAVRNGSIRRR
>NZ_AP022605|974923:1016719|1010129_1010648_-|WP_133055547.1|DBSCAN-SWA
MSARVTRGIWIPLAGALPAQVEAETVYVLPTRTSAEDTDERFPLYTDNVRYLPKVARAGGAAVEFSTPANSRRYLQEFSAVEVWALAVAVVSLASDWLIPTIQHFIEIRRQSQGWTTSEAEALPLKVSIAKLDMNAGISETYELEGSGADVMDALNLLSKGDQRRLTDDLEE
>NZ_AP022605|974923:1016719|994112_996563_+|WP_085190017.1|DBSCAN-SWA
MIQLKAIHIEEFRGIRRLDLNLNCESFVVAGPNGSGKSGVVDAIDFALTGGITRLSGSGTGGVSLLKHGPHVHQRDNPAVARVELTIVDTASGQTGVLTRCIKTAGQYTLEPSSPELVAAVEWAAQHPELTLSRREVIKYVNTEPGKRAQEVQALLKLDRIDDTRRLLRTALSKSSTDEKQSAAKVKDAEDSVRRHLDLSSLLESEILGAVNKHRDVLGIERLGLLTSDTDLSVGAGDPEEPSGFNKASALQDIAVLIDYIDDHAELSAAATELTSELAELERDPSVLDALKHRALVEVGLPLVTDAACPLCDQTWDDVETLRNHLREKLARSEAAKFLQQRVERASERVARQVQRVQALIGAAQPHAVRLGLTSDQATLLEWSADLASFNAALTNVETAREQAARLNSDPLGQPPTLMAILDGIRGALEALPDQGATVSARTALTIAQERWNRLRQVRAEHEKATAAQHTADAVYKTYNDVADSALTNLYKSVEGNFSAYYRQINADDESSFKAGLAPSAGKLDLEVDFYGLGMFPPMAYHSEGHQDGMGVCLYLALIKQLLREDFRIAVLDDVVTSVDTNHRRQFCTLLKDAFPDVQFIITTHDEVWARQMQSSGLIRRRAQARFHGWNVDRGPVYGEGQDFWAQIDADLAKDDVPAAAHKLRRNLEASLADIAAAIQGRIVYRPDNNYDLGSFFSAVKGRHGDLLKKAATSANSWKNEVAKEQVEELKAARQNAMLGQDGENWAINALVHNNDWAVMAKADFTPVVEACKDFLDLFTCRGSECDAWVYVVGLPGKEEAMRCACGTLNLNLRSK
>NZ_AP022605|974923:1016719|1009243_1010167_-|WP_133055546.1|DBSCAN-SWA
MINADSRMTLKNKGLQFKATVVQWGPVPPAGGPSRVRYLDVNGRRALQVADDKFAAVMQMLDAQRGSVPVMHMPLMEDDDDARLRIQSRLRAQWDEFTTTLSPDLLQEIEPRIRKSEKSAVAALNFLEDHNLSETAHEAIHRAAFVRRGLFGCPITFRDGDFWTSCSIRMSHIRIGMSAGLTSEFECSVCDRLVDECDHTTGLTYDKVAERDSAGDCTVCKSKDCEHRIGSTYPILAYGNARNVMAHEVSMVARPRYPQARFTELTLDLSNSRRYEILKWGAEQGYLHCDGCLGPCKGFSGMADAEP
>NZ_AP022605|974923:1016719|1006727_1007219_-|WP_163784088.1|DBSCAN-SWA
MPSSIGIYLALARGKTARVAGPIAGFHVTGPYVRRNLAGVPRGINAIASVYFPPLAWELVHKSNTTLVDDAWVDVSCWTELHPGEIHPFTDLVSGLPAVCHSWHHPSRNEGWAELMDSNLVAIVECFNVEGGPADFATPPTVSKRAHITTDEIETLARRHPMR
>NZ_AP022605|974923:1016719|1014544_1015201_+|WP_085191706.1|DBSCAN-SWA
MVTVEVDSERVESRLAAGEVSCPSCPDGVLVRWGFARSRQVVGSAAPVRPRRSRCRTCLVTHVLLPVTLLLRRAYVAELIWAAVVAKAAGGGHRRIGARLGIPGSTVRGWLRVITGRAQVVRHWFLSVAVAAGVDVSIPRSTGSGCGDVVAAVGAARAAVGARFGERSVIGAVTSARVAAACSGGRLLSPGWPPAPKPVGATPVDPDISGVDGSSSRG
>NZ_AP022605|974923:1016719|998712_998898_-|WP_082967898.1|DBSCAN-SWA
MKMEDNPFKGLPLLLSVPHAAELLGISRAAAYRLVNSGELPVRRLGGRVYVVTSGLRELAS
>NZ_AP022605|974923:1016719|982165_982414_-|WP_085190028.1|DBSCAN-SWA
MSAAETLTMYTTSWCGYCVRLKKALQVEGIPWTEVDIERDSAAADFVMSVNGGNQTVPTVKFADGSALTNPSIKDVKAKLGR

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085190039.1|974923_975412_+|protease	hydrogenase maturation protease	NA	NA	NA	NA
WP_133055529.1|975404_975623_+	hypothetical protein	NA	NA	NA	NA
WP_085190035.1|975712_975964_+	hypothetical protein	NA	NA	NA	NA
WP_085190288.1|975972_977046_-	hydrogenase expression/formation protein HypE	NA	NA	NA	NA
WP_085190034.1|977038_978148_-	hydrogenase formation protein HypD	NA	NA	NA	NA
WP_085190032.1|978144_978429_-	HypC/HybG/HupF family hydrogenase formation chaperone	NA	NA	NA	NA
WP_085190286.1|978371_980732_-	carbamoyltransferase HypF	NA	NA	NA	NA
WP_085190285.1|980895_981258_+	hydrogenase maturation nickel metallochaperone HypA	NA	NA	NA	NA
WP_085190030.1|981267_982059_+	hydrogenase nickel incorporation protein HypB	NA	NA	NA	NA
WP_085190028.1|982165_982414_-	mycoredoxin	NA	NA	NA	NA
WP_085190026.1|982486_984610_+	ATP-dependent DNA helicase UvrD2	A7KV33	Bacillus_phage	9.3e-46	26.4
WP_085190024.1|985109_985391_+	WhiB family transcriptional regulator	NA	NA	NA	NA
WP_085190023.1|985412_986747_-	AarF/ABC1/UbiB kinase family protein	A0A0R6PKQ6	Moraxella_phage	1.4e-20	27.1
WP_085190283.1|986792_987635_-	cyclodehydratase	NA	NA	NA	NA
WP_085190021.1|987723_989139_-|protease	zinc-dependent metalloprotease	NA	NA	NA	NA
WP_085190280.1|989229_990258_+	PDZ domain-containing protein	NA	NA	NA	NA
WP_085190019.1|990342_993354_+	UPF0182 family protein	NA	NA	NA	NA
993535:993551	attL	NA	NA	NA	NA
WP_085190017.1|994112_996563_+	AAA family ATPase	NA	NA	NA	NA
WP_085190015.1|996660_996984_-	XRE family transcriptional regulator	NA	NA	NA	NA
WP_085190014.1|996986_997337_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_109749304.1|997372_998716_-|integrase	site-specific integrase	A0A1B0T6A8	Bacillus_phage	4.1e-47	30.7
WP_082967898.1|998712_998898_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_099050197.1|1000694_1001964_+|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	9.2e-49	39.9
WP_085190276.1|1002028_1002454_+	AAA family ATPase	NA	NA	NA	NA
WP_085190012.1|1004313_1005390_+	AAA family ATPase	NA	NA	NA	NA
WP_085190010.1|1005720_1006521_+|transposase	transposase	NA	NA	NA	NA
WP_163784088.1|1006727_1007219_-	hypothetical protein	NA	NA	NA	NA
WP_133055546.1|1009243_1010167_-	hypothetical protein	NA	NA	NA	NA
WP_133055547.1|1010129_1010648_-	hypothetical protein	NA	NA	NA	NA
WP_085191698.1|1011288_1013619_+	hypothetical protein	NA	NA	NA	NA
WP_085191706.1|1014544_1015201_+	hypothetical protein	NA	NA	NA	NA
WP_085191704.1|1015249_1016719_+|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
1022417:1022433	attR	NA	NA	NA	NA