CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_AP022614	Mycobacterium parmense strain JCM 14742	8 crisprs	DinG,DEDDh,csa3,PD-DExK,WYL,cas4,cas3,RT	3	11	2	0

1. NZ_AP022614

CRISPR-Cas detection and classification

Crispr_ID: NZ_AP022614_1

• CRISPR_ID: NZ_AP022614_1
• CRISPR_location: 1702883-1702971
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_AP022614_1

Consensus_repeat	Method
CCCAGACTCGACGGCAGCGTCAG	CRISPRCasFinder

spacers of NZ_AP022614_1

>1.1|1702906|43|NZ_AP022614|CRISPRCasFinder
CACACCGCCGGTGAGGATCGAGGGGATGCCGACGTCTCCCCCA

CRISPR arrays and Neighbor proteins around NZ_AP022614_1

CRISPR arrays

The CRISPR arrays of NZ_AP022614_1

>merge|NZ_AP022614|1|1702883-1702971|CRISPRCasFinder
CCCAGACTCGACGGCAGCGTCAGCACACCGCCGGTGAGGATCGAGGGGATGCCGACGTCTCCCCCACCCAGGCTCGACGGCAGCGTCAG

>NZ_AP022614|1|1|1702883-1702971|CRISPRCasFinder
CCCAGACTCGACGGCAGCGTCAG	CACACCGCCGGTGAGGATCGAGGGGATGCCGACGTCTCCCCCA
CCCAGGCTCGACGGCAGCGTCAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP022614.1|WP_085271570.1|1719187_1719955_-|GAF-and-ANTAR-domain-containing-protein	unknown	unknown	gnl|CDD|377145
NZ_AP022614.1|WP_085271643.1|1696668_1698474_-|N-acetylglutaminylglutamine-amidotransferase	unknown	unknown	gnl|CDD|274430
NZ_AP022614.1|WP_085271568.1|1710077_1715657_-|type-I-polyketide-synthase	unknown	unknown	gnl|CDD|225858
NZ_AP022614.1|WP_085271569.1|1717827_1719150_+|cation:proton-antiporter	unknown	unknown	gnl|CDD|215608
NZ_AP022614.1|WP_085271562.1|1703884_1704211_-|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132914
NZ_AP022614.1|WP_085271564.1|1706830_1707367_-|hypothetical-protein	unknown	unknown	unknown
NZ_AP022614.1|WP_085271644.1|1698683_1700066_-|OFA-family-MFS-transporter	unknown	unknown	gnl|CDD|340911
NZ_AP022614.1|WP_085271565.1|1707430_1708180_-|hypothetical-protein	unknown	unknown	unknown
NZ_AP022614.1|WP_139825996.1|1692820_1693270_-|hypothetical-protein	unknown	unknown	unknown
NZ_AP022614.1|WP_085271556.1|1693315_1694809_-|MFS-transporter	unknown	unknown	gnl|CDD|365860
NZ_AP022614.1|WP_085271554.1|1690457_1692635_-|glutamine-synthetase-III	unknown	unknown	gnl|CDD|226477
NZ_AP022614.1|WP_085271560.1|1701352_1702384_-|4Fe-4S-binding-protein	unknown	unknown	gnl|CDD|224516
NZ_AP022614.1|WP_085271557.1|1694875_1696672_-|N-acetylglutaminylglutamine-synthetase	unknown	unknown	gnl|CDD|132147
NZ_AP022614.1|WP_085271563.1|1704210_1706748_-|SpoIIE-family-protein-phosphatase	unknown	unknown	gnl|CDD|369272
NZ_AP022614.1|WP_085271567.1|1709187_1710081_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
NZ_AP022614.1|WP_085271566.1|1708330_1709188_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|366444
NZ_AP022614.1|WP_085271558.1|1700340_1700682_+|DUF732-domain-containing-protein	unknown	unknown	gnl|CDD|368380
NZ_AP022614.1|WP_085271559.1|1700731_1701193_-|hypothetical-protein	unknown	unknown	unknown
NZ_AP022614.1|WP_085271645.1|1715751_1717515_-|tryptophan-7-halogenase	unknown	unknown	gnl|CDD|380163
NZ_AP022614.1|WP_169718465.1|1702538_1702709_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP022614.1|WP_085271556.1|1693315_1694809_-|MFS-transporter	gnl|CDD|365860	pfam00083, Sugar_tr, Sugar (and other) transporter.	1.91772e-38
NZ_AP022614.1|WP_085271643.1|1696668_1698474_-|N-acetylglutaminylglutamine-amidotransferase	gnl|CDD|274430	TIGR03104, trio_amidotrans, asparagine synthase family amidotransferase. Members of this protein family are closely related to several isoforms of asparagine synthetase (glutamine amidotransferase) and typically have been given this name in genome annotation to date. Each is part of a conserved three-gene cassette sparsely distributed across at least twenty different species known so far, including alpha, beta, and gamma Proteobacteria, Mycobacterium, and Prosthecochloris, which is a member of the Chlorobi. The other two members of the cassette are a probable protease and a member of the GNAT family of acetyltransferases.	0
NZ_AP022614.1|WP_085271645.1|1715751_1717515_-|tryptophan-7-halogenase	gnl|CDD|380163	NF033113, halo_ClmS, chloramphenicol-biosynthetic FADH2-dependent halogenase CmlS.	2.12484e-14
NZ_AP022614.1|WP_085271562.1|1703884_1704211_-|STAS-domain-containing-protein	gnl|CDD|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	1.34685e-12
NZ_AP022614.1|WP_085271644.1|1698683_1700066_-|OFA-family-MFS-transporter	gnl|CDD|340911	cd17353, MFS_OFA_like, Oxalate:formate antiporter (OFA) and similar proteins of the Major Facilitator Superfamily of transporters. This subfamily is composed of Oxalobacter formigenes oxalate:formate antiporter (OFA or OxlT) and similar proteins. O. formigenes, a commensal found in the gut of animals and humans, plays an important role in clearing dietary oxalate from the intestinal tract, which is carried out by OFA/OxlT, an anion transporter that facilitates the exchange of divalent oxalate with monovalent formate, the product of oxalate decarboxylation. This exchange generates an electrochemical proton gradient and is the source of energy for ATP synthesis in this cell. The OFA-like subfamily belongs to the Monocarboxylate transporter -like (MCT-like) family of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.25468e-108
NZ_AP022614.1|WP_085271569.1|1717827_1719150_+|cation:proton-antiporter	gnl|CDD|215608	PLN03159, PLN03159, cation/H(+) antiporter 15; Provisional.	6.12409e-65
NZ_AP022614.1|WP_085271563.1|1704210_1706748_-|SpoIIE-family-protein-phosphatase	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	4.03254e-44
NZ_AP022614.1|WP_085271554.1|1690457_1692635_-|glutamine-synthetase-III	gnl|CDD|226477	COG3968, COG3968, Uncharacterized protein related to glutamine synthetase [General function prediction only].	0
NZ_AP022614.1|WP_085271560.1|1701352_1702384_-|4Fe-4S-binding-protein	gnl|CDD|224516	COG1600, COG1600, Uncharacterized Fe-S protein [Energy production and conversion].	2.68453e-17
NZ_AP022614.1|WP_085271557.1|1694875_1696672_-|N-acetylglutaminylglutamine-synthetase	gnl|CDD|132147	TIGR03103, trio_acet_GNAT, GNAT-family acetyltransferase TIGR03103. Members of this protein family belong to the GNAT family of acetyltransferases. Each is part of a conserved three-gene cassette sparsely distributed across at least twenty different species known so far, including alpha, beta, and gamma Proteobacteria, Mycobacterium, and Prosthecochloris, which is a member of the Chlorobi. The other two members of the cassette are a probable protease and an asparagine synthetase family protein.	0
NZ_AP022614.1|WP_085271568.1|1710077_1715657_-|type-I-polyketide-synthase	gnl|CDD|225858	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	0
NZ_AP022614.1|WP_085271566.1|1708330_1709188_-|ABC-transporter-permease	gnl|CDD|366444	pfam01061, ABC2_membrane, ABC-2 type transporter.	3.52439e-16
NZ_AP022614.1|WP_085271567.1|1709187_1710081_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.17379e-86
NZ_AP022614.1|WP_085271570.1|1719187_1719955_-|GAF-and-ANTAR-domain-containing-protein	gnl|CDD|377145	pfam03861, ANTAR, ANTAR domain. ANTAR (AmiR and NasR transcription antitermination regulators) is an RNA-binding domain found in bacterial transcription antitermination regulatory proteins. The majority of the domain consists of a coiled-coil.	2.93696e-14
NZ_AP022614.1|WP_085271558.1|1700340_1700682_+|DUF732-domain-containing-protein	gnl|CDD|368380	pfam05305, DUF732, Protein of unknown function (DUF732). This family consists of several uncharacterized Mycobacterium tuberculosis and leprae proteins of unknown function.	8.89936e-18

Protein sequences

>NZ_AP022614.1|WP_169718465.1|1702538_1702709_+|hypothetical-protein
MDQQINTDAPMEAPKDARKATEEQQELQEQLDHQNEDPDGPALHQSRHDVADESRR
>NZ_AP022614.1|WP_085271560.1|1701352_1702384_-|4Fe-4S-binding-protein
MTERHAGRLAEHPTVRKMRSRPRTTPGPLDAGRLREMCLAAGVDDVAFAAVDNPALASELEHVEAALPGTRSYISLVVKMNRDNVRSTARSVANQEFHRSGEVLNEAAHRIVRRLQDAGYRALNPSATFPMEMDNFPGRIWVVAHKPVAVAAGLGVMGIHRNVIHPKFGNFILLGTILVDAPITSYGEPLDYSPCLECKLCVAACPVGAIGKNGEFDFVSCSVHNYREFMGGFTDWVQTVADSADANEFRSRVSDSENASMWQSLAFKPNYKAAYCLAVCPAGEEVIEPYLDDRKGFMDLVLKPLQDKKETLYVLPDSPAKAHAERRYPHKRVKVVDSGIRGR
>NZ_AP022614.1|WP_085271559.1|1700731_1701193_-|hypothetical-protein
MDTDTVDRQFSALQQQAQQTGTLIQTLANKMSAAAAAGDAHAREWALDLKEIALAIREEQSTTTELLQAIHALVDTHVAAAEPPAPQYYPPAAPYAQAPQYQAAAPFPQPYQPPAASGGGLQRFLSGRFGQAIVTGAGIGIGDDIVNSIFDRL
>NZ_AP022614.1|WP_085271558.1|1700340_1700682_+|DUF732-domain-containing-protein
MTPRHAHRGKRSALGALALSAGALFAASPATADPTDDGFVAALRKNGIVINDPATAVALAHGVCAGFDKGETPRFVAMSLIKDTNLSPEKSGFFMVVAVADYCPNHQGALASS
>NZ_AP022614.1|WP_085271644.1|1698683_1700066_-|OFA-family-MFS-transporter
MQSAGVLSRRRVVAGLGWNRWLVPPAALSIHLAIGSVYSWSVFKLPLHETMGASGLLTALPFTLGIVMLGMSAAVLGTTVERRGPRWAMLVATSCFSGGLLVAAVAAQYGQMWLIIVGYGLIGGIGLGIGYISPVSTLMKWFPDRPGMATGFAIMGFGGGALIASPWSAQLMKWFGTDRHGLAATFFTMGVVYAAFMSLGVVLVRVPPPEWEPPVVRTVTPKRTQRAAGPDRTASEAIRTPQFWLLWVVLCFNVTAGIGILERAAPIYRDYFPHAGSKAALTAAAAGFVALLSLANSAGRILWSSVSDSAGRKNIYRLYLGVGALLYLVLIVAQNASKPLFLVVCIVLLSFYGAGFATAPAYLRDLFGYQQVGAIHGRLLTAWSVAGVLGPVIVNAIADDRVAAGAVGPDRYRWSFAIMVVLLLIGAVCNELIRTPAPPDPIAAPTDARRTAGAAPAKER
>NZ_AP022614.1|WP_085271643.1|1696668_1698474_-|N-acetylglutaminylglutamine-amidotransferase
MCGVTGEVRLDGRIPDVAAVTAMAAVLAPRGPDAAGAWSQGRTALGHRRLRIIDLTEAGAQPMVDAELGLAIAWNGCIYNYQDLRRELEGHGYRFFSHSDTEVLLKAYHRWGDDFVRHLHGMFAFAIVERDSGRVLLGRDRLGIKPLYLTEDGDRIRFASTLPALLAGGGVDTRIDATALHHYMTFHSVVPPPLTILRGVRKVAPGSLVAIEPDGRRTSRTYWTPDFTRHDDRAGWSETDWEDAVLDALRVAVKRRLVADVPVGCLLSGGVDSSLIVGLLAEAGQHGLMTFSIGFEAAGGVEGDEFRWSDIIAKRFGTDHHQIRIGTDRMLPALDGAIGAMSEPMVSHDCVAFYLLSQEVSRHVKVVQSGQGADEVFAGYHWYPPMGSPAAASLEGAVAEYRGAFFDRDAAGVRDLLGRAYFADGDPSGRFVTEHFARAGAETGVDRALRLDTTVMLVDDPVKRVDNMTMAWGLEGRVPFLDHELVELAATCPPELKTAHEGKGVLKQAARRVIPSEVIDRPKGYFPVPALTHLEGPYLEMVRDALYSPVAKERGLFRADAVDALLADPNGKLTPLRGNELWQIALLELWLQRHGVTGPAA
>NZ_AP022614.1|WP_085271557.1|1694875_1696672_-|N-acetylglutaminylglutamine-synthetase
MTVTDPSDEHTEAITLGLHDASPQHLMDAMVKDVELEMGWGRLIFGQTFEDADTLAEALRRETPGRRDICIYARESHVVIAGAPTELFIDPSHTYRLRFTGDSDSDEPSPRPPGVAVRTLENPDDADAMNRVYVRCGMVPAPVEIIWHNHEQVQAVTYLIAVRDGDGAVVGTVTGVDHELLFSDPERGSSLWTLAVDPAAGIPGIGEALTRALAEHFRRAGRSYMDLSVAHDNAAAIRLYEKLGFRRVPVLAIKRKNAINEPLFTAPPETIDDLNPYARIIADEALRRGIWVEVLDAETGEIRLTHGGRSVITRESLSEFTSAVAMCRCDDKRLTRRLVADAGITVPRARLATFDDEDYAFLQEVGEVVVKPTRGEQGKGITVGVLADRGPDELTAAVARAREQFFEVLIEERVTGDDLRLVVIDGRVVAAALRLPPEVIGTGEHTVRDLIAAESRRRSAATGGESRIPIDDVTEATVAEYGWRLDDVLPQGVRLRVRHTANLHQGGTIHDVTAQVNPELCRVAVAAADAIGIPVTGIDLLVPDITGTDYAFIEANERPGLANHEPQPTAAAFLDFLFPGHPGQPPAWTPEESRHARD
>NZ_AP022614.1|WP_085271556.1|1693315_1694809_-|MFS-transporter
MSDGVQTGTITTRVPARLDRLPWSRFHWRVVIGLGGVWVLDGLEVTMVGNVSARLTEKGSGIALDPAQIGVAAAIYITGACLGALFFGHLTDRFGRRNLFILTLALYLVSTVATAFAFAPWYFFVTRFFTGAGIGGEYAAINSAIDELIPARVRGRVDLLINGTYWLGSAAGAAGALVVLDTSNFPANIGWRLAFGIGAILGIFVLLVRRNVPESPRWLFIHGRDEEAERIVGEIETDVEAHTGEPLPEPEGRPLRIRQRESISFTEIARVAFTLYPGRAVLGLALFIGQAFLYNGVTFNLGTLLSNFYGVPSGKVPLFFILWALSNFLGPLLLGRLFDTVGRKPMITLSYLGSAAVAAALAVLFERGTGGVWAFIVVLAVTFFVASAGASAAYLTVSEIFPMETRALAIAFFYAVGTAIGGIAGPLLFGQLINSGDRGQVMWSFLIGAAVMAAAGLVELRLGVAAEQRSLEDLALPLTVADAQEDEPSPDSRGAAR
>NZ_AP022614.1|WP_139825996.1|1692820_1693270_-|hypothetical-protein
MREWLALCAGIALIPWTIFLALTLPQSYPAQHWELTWVGFDVLLLGFMIATAVLGFMQHRLLTLFAFTTGVLLICDAWFDVLTARRADFVVSVLTAALGELPLAAVLIVGTLRIMRLQVPSLSRVWWLFPGRREFAKTRREPFDRHTRR
>NZ_AP022614.1|WP_085271554.1|1690457_1692635_-|glutamine-synthetase-III
MSGNAVRLEAINNVEAYVPPANSFVPGEQPGEVFGSNVFTKSEMQARLPKAVFKSVVATLEKGAKLDPAVADTVAVAMKDWALEKGATHYAHVFYPMTGLTAEKHDSFLEPVSDGATLAEFAGKTLIQGEPDASSFPSGGLRSTFEARGYTGWDVTSPAYILDNPNGKTLCIPTVFVSMTGEALDYKTPLLRSQQAMGAQAERILKLFGHKDLNHVVSFCGPEQEYFLIDRHFFLARPDLVNAGRTLFGAKPPKGQEFDDHYFGAVPERVLAFMMDTERELFKLGIPAKTRHNEVAPGQFEIAPMFERANIASDHQQLLMTIFKTVAKKHGMECLFHEKPFAGVNGSGKHVNFSMGNSDLGSLLVPGDTPHENAQFLVFCAAVIRAVHKFAGLLRVSVASATNDHRLGANEAPPAIISIFLGEQLADVFEQIAKGAATSSKGKGTMIIGVDTLPPLPTDPGDRNRTSPFAFTGNRFEFRAPGSGQTVAVPMIVLNTIMADSFDYMATILEKAVEEGGDFDQAVQQLLTDVITEHGAVVYNGDGYSEKWQLEAAERGLPNLKTSLDAIPELIKPEAVELFEKYGVFNERELHSRYEVRLEQYALTIGVEAKLALEIGTTVILPAAIRYQTELAQNVAALKQAGVEASTAALEAVSAPIADLQTGLSSLKSALADHSAETALDEAKHAQEALLPAMAAVRAAADTLESLVADDLWPLPTYQEMLYIL
>NZ_AP022614.1|WP_085271562.1|1703884_1704211_-|STAS-domain-containing-protein
MPTSLSLDTARRDDGKLVLIATGEIDLSNVDAFNNAISTVSSEGSGRGGKVTVDLSAVDYLDSAAINVLFARADHISLVAQPLLMSLLHISGLSELVTVEPAAPAPEG
>NZ_AP022614.1|WP_085271563.1|1704210_1706748_-|SpoIIE-family-protein-phosphatase
MPNAGGESTAGHERLDELVAARDQMQHLVRVIVEISSNLDLDVTLHRIVNAAMELTDAPYGALGIRASDGSMVSFVHAGIDDDTARRLGRLPVCEGLRIDEASAHPQGDGLQAHEPRIRAVLGMPITVRAADFGSLYLADDRPGRTFSDAHEDAVRALATAAAAAIDNARLFERERESAKWTKASREITTALLSGDPQTGPLQLIVNLALELADAEQAILLVPREPELHSDDVDTLVVAATAGRYASEVIGQQVPMDASTTGGVARRGLPLITDSFQYPIEGFTDVGERSAIVMPLIADDRVLGVIAVARHPQQPAFDNEYLELVSDFARHASIALALAASREQALNQQLAQSDTVDDAVRAAAEELRRLWRARRVLAVTFPSRGPSARITSPAPEVVAVGEPAQWGDLPAHTRQQLSSLRDGDLLTPNTATPGTAGIALQHPEGVLVVWLDLTDQRPFTLEDQTLLTVLAGRLGQGLQRVHQVDQQRETALALQHAILGPAQLPDGFTVRYQAASRPLQVGGDWYDIVDLEDGRIALIVGDCVGHGLAAATVMGQVRSACRALLFENPSPGAALAGMDRFAARLPGAQCTTAVCAVLDPDTGELVYSSAGHPPPILVHADGTTQMLDGGHTIALGVRPDWARPEARVTVPARATLLLYTDGLVERRRNALEQGISRAADLVATARALDLEDLANHIMSGLAPSGGYQDDVVLLLYRHPAPLEMEFPANVSQLAPTRAALRSWLTRVQVDPDQAMSVLVAAGEAVANAIEHGHRHSPEGTITLGATALVDQLRVTVTDTGSWKPPQPDPDVSRGRGIALMQKLMEDVSISPDAAGTTVHLAVRIV
>NZ_AP022614.1|WP_085271564.1|1706830_1707367_-|hypothetical-protein
MLAAFGFEALGVVVGDMYFVDPSPLEGQETPERGVRLELRLIEKGDPQGSIYAGVPIAFSRPVWRVDLFGSTESPPGTLDRAHHHPRFNGWEPGRRHFVPELSADPVSWLAGQLADPTAVLARAGIDTDEVFEADLTGLAAAAPDIVAAVKRMLDGVRDGQLAPSPPEPVAAARTGWL
>NZ_AP022614.1|WP_085271565.1|1707430_1708180_-|hypothetical-protein
MSNDESLLGTFPGRLFLRELRPRVPASIAAMGPMELISAATRAVGSYLYADECPAVLNLDVNREQLRDLAAAALAALSSLSTFGSPQMHQGALTTLHRPNPANRNPLSALPDGAFWTSTPLTAGDDSWTVSGENLRRDQPRRAVHFDETQVRLVRIDSAADWQQFIESNPVTDGGRRYPDWPTMSHSWDAVHLSPAGLLLAHPAISTTPLSCTDGSGLAHSRAGRYASVADWSAVSTAWLHEPPGAQIV
>NZ_AP022614.1|WP_085271566.1|1708330_1709188_-|ABC-transporter-permease
MNLLPTDSGSPTRHGRAEPRSQLPSPLRIGLSRVVPELKMFYRRPEQVVLTFSLPAVICVLLGSIFSTRLPHLGISTGAVIAASMLAYGILSTSFINLGISIAADRDTGALRRLRGTPTTALSYFVGKISLVAIASLAEAVLLLSVGLLFFGLRLPATIFGWFTLTWVFLLGIVSCSLLGIFISNLASNAVAAAVVTNGPAVGLQFVSGTYVPLAVLPGWMLTLGSLFPVKWMAQGFRSVLLPPDLAAFEPAGNWEHWHIFLVLTAWTIGGLAACLAVFRWTDKS
>NZ_AP022614.1|WP_085271567.1|1709187_1710081_-|ABC-transporter-ATP-binding-protein
MSRTLRRQNGSAPAVTHTDRSSAVMVRGLSKSYGRVPAVRDLDLDVSYGEIFAILGPNGAGKSTTIEILEGHRKRDAGYARVLGEDPGVAGRSWRAKIGIVLQEASDAGMLTVSETVRMFADCHAQARAPQEVLELVGLASLGNSRVRTLSGGQRRRLDVAIGIINVPSLLFLDEPTTGFDPEARRRFWDLIRLLAADGTTIVLTTHYLDEAAALADRVAVIAGGRVVAVDSPQRLIDYVSSTATVRWRQGDDIYVEQTDHPTELIRRRSQDGTELAELTVSRPTLEDAYLHLIGLS
>NZ_AP022614.1|WP_085271568.1|1710077_1715657_-|type-I-polyketide-synthase
MLAEPGSRTPLAIVGIGCRFPGGADTPEDYWRLLCGETDATRTVPESRWSAQRYHDPNPAKVGKMVTRRGGFLCEIDQFDPQFFGISPREANLLDPQQRLLLRTTWEALEDGGIPAESLAGTEVGVFVGGFTLDYQLLQNQGRTSRYRFKTHSATGMMMTMLANRISFAFDFRGPSMTIDTACSSSLVAVHLAALSIWNGECDVALAGGVNVMIGPNTAIAESKSGFLSPDGRCKAFDESADGYARGEGGAMVVIKPLEAALRNGDEIYAQILGSAVSQDGHTDAITVPSAEAQEAAIRAALRHAGVPAEEVGYVEAHGTGTPVGDPVEVRALANALALQRPAANPLLIGSVKTNIGHLEAGAGVAGLIKTALVLKSGYIPATLHLTKPSPRIPLSEWGIDIPRSGRPFPVGKRRVAGVNSFGFGGTNAHVVLAEPPATTGVTGPQDWRKLPTAVLPISARTEEALVATARRLAEHLDANPGLRLLDLGYTLSQRRSQLNCRTTLVVDGVADAHEQLRAIADSGRVVAKRTAAPAPALAFVCTGMGPQWWKMCRGLLDVYPAFTESIRRSDRELSKYVGWSLIEELLTDETRSRMGETDVAQPANFAIQVALAEQLKQFGVYPDAVVGHSAGEVAAHYLAGVLTFEQAVHLIYQRSRLQQRTSGLGHMLAVGLSAESFTQIVDARTRDDEDRRLSVAAINGPSSITLAGDSEVLEDVARQLEVEGIFHRYLTGKVPYHSHFMDAVKDDLNSVLEQLSPGAATIPLYSTVTGERLARYADGAAYWWQNTRATVLFEPAVRRMLDDGYTHFVELGPHPVLASSLLDIAATQHTDCVVVAAQRRNDDDGRTLMHCVGTLHCHGHPIAWEALYPPGEGRRLKLPLYPWQSKRFWNETQEAAEDLHYNPVHPLLGQPVSGIHPAWEVELNTATTPLLADHRVQGSTVLPGAVYIEMALAAAKVTYGTVDYSVDQLTFRRALILDDTCDPVLRTTLNRDAGTVEFAALTATAGGDVKWTITATAELNTLARSSVPALGPTGTPPQTATDGDEFYARARAAGFDYGDAFQTITRITSGEGWATAHLAPPTALGEELDEYRFHPVLIDGAFQTLIGTAALGREADDSPHLPVRIRRSAIYAAPQHDMTAHVRVVSTTSDEVESDIVITGDDGQTLAVFTGFTLQALSNSSHLSPERIDKGLYEIHWVAQRGVPDERPATASPPERLSWLILVDAGGVGTSLAEQLRRSGQQVRKVLRRPVPALAKVDGGYALNPRQPEQLRQLLDTHLATDGSLTGIIDCWPLDICAEPRRGAVADTADTNDDVGVFTILNLVKAVTEHGVFQPRLYLITANAQPAPGTEALNVHQAAIWGLGRVIGHQEFAGQWGGLIDIDDADGGVGSAARICEHILTDDPEDQIAIRDHTTFVPRVRSSSILTQAFPTKLSPDATYVVTGGAGALGRVVALYLAERGARHIALLVRSQIPPRAQWSSLPADHRHRPTVDMIGKVERLGARVSTASVDITRADQVEKWLSGHLGEGGRPVRGIIHAAGTVDDRLLVNMTEADFAAVMAPKVDGARVLHEAFRDHELEFFVMFGSAGSVVTAPGQGNYAAANAFLDAFAHYRQAQGLPALTIGWGPWSAGMVEELKLEEIYAQRGIELITPAAGTRILDRLINQKAPNVIAIGADWGRVLRVGFGRELPPMFSELRTAEIDSETVDSESSMVEFLSRCPEADRLDVVARQVRNIVAAVFELAVDDIAPDDALDDIGLDSMMAMDFRLRISGAFGMDIPLLELLRGVSVNSLAVRILNELCLTAAQPPEDSGDRPGSAEADDAVDRLLEQSSEAELRELLAELEGQPIEQDTREMRA
>NZ_AP022614.1|WP_085271645.1|1715751_1717515_-|tryptophan-7-halogenase
MQAQLSQLNPEARAALAQKIRTRLSGGDGSGATHDVAVVGGGAAALTLALGLRRTRPRTRILVIDPHPHPVPEITHTVGESTVEISAHYLRDRLGLGDHLHTSQIRKMGLRMFFSHDGNTDIAQRMELGSSSFIPQVTYQIDRGRLENELHRLCVSEGVEITSGRVRSVELGQLGRPHSLRIQRGNTTTHTTARWVVDASGRNRTLPRQLGLRLANEHRCNAAWLRVATEIDIGRWSDDPAWRSRLVEGDRAMSTNHLMGEGYWVWLIRLASGSTSVGIVADPAFHPFDGFNTLAKARSWLSEHEPQCAAVLDRHAHLIKDFRVMRNYSHTVTKVYDGQSRWCLTGDSGVFLDPLYSSGLDLIAIGNELITDMIVRELDGEDVVARAGINDSLFRSLAEMWLNVYCGQYPLMGSPAIMSAKVVWDIAFYWGFLGLLYSNGRFLTVADDPGVVPALEGLIELSNRMQLFFREWAAVERGCPAVQFVDLYSPLNFMVTLHTAMMGKAPDFTARFDANIRLLRRLAGQLIETVVTDKCDAFCEDDVMRQVQAWQRDSLLRDLRSTYRHGQHHDPLSANWIVETATALEFS
>NZ_AP022614.1|WP_085271569.1|1717827_1719150_+|cation:proton-antiporter
MPTAVAAHLFLALAVILGACRLVGLVSQRLGQPQVVGEMVAGVLLGPSLLGRIAPALQHHVFPTGPTTIVLYTTAQIGLVLYMFLIGLNFDAGLLKHRVGTAAAVSAAGILVPLALGALVAVPLLTTGRYFDKSVTLVMAMMFLGASIATTAFPMLARIIYERGLSGTPLGTLALACGATDDAFSWCILATVLAIHRGSAAVAATAILGGIAYALLVLTVGRKALRVLGTVSERRKTVTPAVLSAVLILLMACAWLTDSIGIYAIFGAFVLGVAMPSGFFAQRLTASLEPIVTTFLLPLFFVYSGLNTRIGLVNSPALWAATLGLLAVSIAGKGIACTLAARLRRVPLRESMALGSLMNARGLIELILLNIGLEAGIITPTLFSILVIVAVVTTLMATPVFELVYGRHLKVPQSDRAQASPPDPRARSTRAAPDVATQPG
>NZ_AP022614.1|WP_085271570.1|1719187_1719955_-|GAF-and-ANTAR-domain-containing-protein
MASVLEPVSPSGEQSDGQVPTTPRELDLLTDGAWSCLQQLARSLRVDEADRDATLKAIVVKATATIDPVEAAGVILLEKGKVIPQAVHGEAPAVLDRLQQRTGAGPCIDASRDQRSVEITDMRTDGRWPKFGQRAIELGVHSMLCLPLWIDDRTLGSLSLYAGLPAAFEDTARRFAELFATHAALAIGDAQRTGRLRRAMINRDLIGQAKGILMERHRITADEAHDLLVRASKHTNRKVVDLAGDLVTTGGVHIP

Crispr_ID: NZ_AP022614_2

• CRISPR_ID: NZ_AP022614_2
• CRISPR_location: 1900913-1900991
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_AP022614_2

Consensus_repeat	Method
CCGGCCCCGCCGTTGCCGCCGTTACCG	CRISPRCasFinder

spacers of NZ_AP022614_2

>2.1|1900940|24|NZ_AP022614|CRISPRCasFinder
CCGTTGCCGCCGGGGCCGACGCTG

CRISPR arrays and Neighbor proteins around NZ_AP022614_2

CRISPR arrays

The CRISPR arrays of NZ_AP022614_2

>merge|NZ_AP022614|2|1900913-1900991|CRISPRCasFinder
CCGAGGAACGCGTTGCCGCCGTTGCCGCCGTTGCCGCCGGGGCCGACGCTGCCGGTGCCACCGTTGCCGCCGGCGCCGC

>NZ_AP022614|2|2|1900913-1900991|CRISPRCasFinder
CCGAGGAACGCGTTGCCGCCGTTGCCG	CCGTTGCCGCCGGGGCCGACGCTG
CCGGTGCCACCGTTGCCGCCGGCGCCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP022614.1|WP_085269530.1|1942497_1943232_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379276
NZ_AP022614.1|WP_139825911.1|1922192_1926749_-|amino-acid-adenylation-domain-containing-protein	unknown	unknown	gnl|CDD|237108
NZ_AP022614.1|WP_139825910.1|1927448_1928579_+|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|379312
NZ_AP022614.1|WP_085270773.1|1893398_1894739_+|lipase	unknown	unknown	gnl|CDD|367570
NZ_AP022614.1|WP_085270700.1|1895395_1895635_-|hypothetical-protein	unknown	unknown	unknown
NZ_AP022614.1|WP_139825912.1|1909645_1922206_-|amino-acid-adenylation-domain-containing-protein	unknown	unknown	gnl|CDD|237108
NZ_AP022614.1|WP_085270772.1|1895654_1896692_-|biotin-synthase-BioB	unknown	unknown	gnl|CDD|235755
NZ_AP022614.1|WP_163670809.1|1928589_1939611_-|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|225858
NZ_AP022614.1|WP_085270697.1|1898009_1899158_-|8-amino-7-oxononanoate-synthase	unknown	unknown	gnl|CDD|235655
NZ_AP022614.1|WP_085269528.1|1940016_1941285_-|glycosyltransferase	unknown	unknown	gnl|CDD|224732
NZ_AP022614.1|WP_085270701.1|1894748_1895399_-|DUF2567-domain-containing-protein	unknown	unknown	gnl|CDD|371258
NZ_AP022614.1|WP_085270698.1|1897332_1898013_-|ATP-dependent-dethiobiotin-synthetase-BioD	unknown	unknown	gnl|CDD|234625
NZ_AP022614.1|WP_085270704.1|1889790_1891374_-|L-aspartate-oxidase	unknown	unknown	gnl|CDD|236102
NZ_AP022614.1|WP_085270702.1|1892475_1893219_+|NUDIX-hydrolase	unknown	unknown	gnl|CDD|223979
NZ_AP022614.1|WP_085270771.1|1908980_1909637_+|isoprenylcysteine-carboxylmethyltransferase-family-protein	unknown	unknown	gnl|CDD|224931
NZ_AP022614.1|WP_085270694.1|1926754_1926985_-|MbtH-family-protein	unknown	unknown	gnl|CDD|377081
NZ_AP022614.1|WP_085270699.1|1896826_1897333_-|2'-5'-RNA-ligase-family-protein	unknown	unknown	gnl|CDD|379265
NZ_AP022614.1|WP_085269531.1|1941741_1942464_+|rhamnosyl-O-methyltransferase	unknown	unknown	gnl|CDD|226041
NZ_AP022614.1|WP_085270695.1|1902649_1908925_+|type-I-polyketide-synthase	unknown	unknown	gnl|CDD|225858
NZ_AP022614.1|WP_085270703.1|1891370_1892429_-|quinolinate-synthase-NadA	unknown	unknown	gnl|CDD|236489

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP022614.1|WP_139825911.1|1922192_1926749_-|amino-acid-adenylation-domain-containing-protein	gnl|CDD|237108	PRK12467, PRK12467, peptide synthase; Provisional.	0
NZ_AP022614.1|WP_139825910.1|1927448_1928579_+|methyltransferase-domain-containing-protein	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	2.73375e-22
NZ_AP022614.1|WP_085270773.1|1893398_1894739_+|lipase	gnl|CDD|367570	pfam03583, LIP, Secretory lipase. These lipases are expressed and secreted during the infection cycle of these pathogens. In particular, C. albicans has a large number of different lipases, possibly reflecting broad lipolytic activity, which may contribute to the persistence and virulence of C. albicans in human tissue.	8.65547e-109
NZ_AP022614.1|WP_085270704.1|1889790_1891374_-|L-aspartate-oxidase	gnl|CDD|236102	PRK07804, PRK07804, L-aspartate oxidase; Provisional.	0
NZ_AP022614.1|WP_139825912.1|1909645_1922206_-|amino-acid-adenylation-domain-containing-protein	gnl|CDD|237108	PRK12467, PRK12467, peptide synthase; Provisional.	0
NZ_AP022614.1|WP_085270772.1|1895654_1896692_-|biotin-synthase-BioB	gnl|CDD|235755	PRK06256, PRK06256, biotin synthase; Validated.	0
NZ_AP022614.1|WP_163670809.1|1928589_1939611_-|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|225858	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	0
NZ_AP022614.1|WP_085270697.1|1898009_1899158_-|8-amino-7-oxononanoate-synthase	gnl|CDD|235655	PRK05958, PRK05958, 8-amino-7-oxononanoate synthase; Reviewed.	1.47739e-175
NZ_AP022614.1|WP_085269528.1|1940016_1941285_-|glycosyltransferase	gnl|CDD|224732	COG1819, COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms].	3.25589e-62
NZ_AP022614.1|WP_085270701.1|1894748_1895399_-|DUF2567-domain-containing-protein	gnl|CDD|371258	pfam10821, DUF2567, Protein of unknown function (DUF2567). This is a bacterial family of proteins with unknown function.	2.12756e-64
NZ_AP022614.1|WP_085270698.1|1897332_1898013_-|ATP-dependent-dethiobiotin-synthetase-BioD	gnl|CDD|234625	PRK00090, bioD, ATP-dependent dethiobiotin synthetase BioD.	4.29421e-63
NZ_AP022614.1|WP_085270694.1|1926754_1926985_-|MbtH-family-protein	gnl|CDD|377081	pfam03621, MbtH, MbtH-like protein. This domain is found in the MbtH protein as well as at the N-terminus of the antibiotic synthesis protein NIKP1. MbtH and its homologs were first noted in gene clusters involved in non-ribosomal peptides and other secondary metabolites by Quadri et al. This domain is about 70 amino acids long and contains 3 fully conserved tryptophan residues. The structure of the PA2412 protein shows it adopts a beta-beta-beta-alpha-alpha topology with the short C-terminal helix forming the tip of an overall arrowhead shape. MbtH proteins have been shown to be required for the synthesis of antibiotics, siderophores and glycopeptidolipids.	1.54967e-31
NZ_AP022614.1|WP_085270702.1|1892475_1893219_+|NUDIX-hydrolase	gnl|CDD|223979	COG1051, COG1051, ADP-ribose pyrophosphatase [Nucleotide transport and metabolism].	3.39243e-24
NZ_AP022614.1|WP_085270771.1|1908980_1909637_+|isoprenylcysteine-carboxylmethyltransferase-family-protein	gnl|CDD|224931	COG2020, STE14, Putative protein-S-isoprenylcysteine methyltransferase [Posttranslational modification, protein turnover, chaperones].	1.22517e-24
NZ_AP022614.1|WP_085269530.1|1942497_1943232_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|379276	pfam13578, Methyltransf_24, Methyltransferase domain. This family appears to be a methyltransferase domain.	2.65255e-16
NZ_AP022614.1|WP_085270699.1|1896826_1897333_-|2'-5'-RNA-ligase-family-protein	gnl|CDD|379265	pfam13563, 2_5_RNA_ligase2, 2'-5' RNA ligase superfamily. This family contains proteins related to pfam02834. These proteins are likely to be enzymes, but they may not share the RNA ligase activity.	8.60095e-05
NZ_AP022614.1|WP_085269531.1|1941741_1942464_+|rhamnosyl-O-methyltransferase	gnl|CDD|226041	COG3510, CmcI, Cephalosporin hydroxylase [Defense mechanisms].	7.07888e-105
NZ_AP022614.1|WP_085270695.1|1902649_1908925_+|type-I-polyketide-synthase	gnl|CDD|225858	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	0
NZ_AP022614.1|WP_085270703.1|1891370_1892429_-|quinolinate-synthase-NadA	gnl|CDD|236489	PRK09375, PRK09375, quinolinate synthase NadA.	6.70176e-170

Protein sequences

>NZ_AP022614.1|WP_085270697.1|1898009_1899158_-|8-amino-7-oxononanoate-synthase
MKAPIDASPLAWLSQRETQRREAGLRRTLRPRPAVATELDLASNDYLGLSQHPDVIEGGVAALRIWGAGSTGSRLVTGDTELHQQFESDLADFVGAPSALLFSSGYAANLGAVVGLSGRGSLLVSDALSHASLVDACRLSRARVAVTPHRDVDAVEAALRSRDEERAVVITESVFSADGALAPVRELHQACRRHGALLVVDEAHGLGVRGGGRGLLHELGLAGAPDVVMTTTLSKALGSQGGAVLGPAAVRAHLIDAARTFIFDTGLAPAAVGAALAALAVLRAEPWRPDAVLRHARDLARICGVTAVPQSAVVSVILGEPEVAVAAAAACLDAGVRVGCFRPPTVPVGTSRLRLTARASLSDAELDLARQVLTDVLSFPRR
>NZ_AP022614.1|WP_085270698.1|1897332_1898013_-|ATP-dependent-dethiobiotin-synthetase-BioD
MTVLVVTGTGTGVGKTVVTAALACHARLAGVDVAVCKPVQTGTGAGDDDLAEVARLSGVGELAGLARYPQPLAPAAAAERAGMALPTRDQLLRLISGLDRPGRLTLVEGAGGLLVELAGGGVTLRDLAVDLGAAVLVVAAAGLGTLNHTALTLEALVSHDVSCAGVVIGSWPRRVGTVETSNREALARMAAVRAALPAGAASMDGGEFADMSAAAFDRDWVTSLVG
>NZ_AP022614.1|WP_085270699.1|1896826_1897333_-|2'-5'-RNA-ligase-family-protein
MVHSIELLFDAGTEAALRQIWDDLAGADIAGRPPPGRPHVTLVVAERIAADVDAALRPLTGLLPLRCTVGASLLLGRSNAILARLIVPTVAMLDLHAQVYHRCVEHLLPAPAPHSLPGQWTPHVTLARRVEGPALSAALRVAGRPPQLQGGFAGLRRWDGDAKVDYLL
>NZ_AP022614.1|WP_085270772.1|1895654_1896692_-|biotin-synthase-BioB
MTQAATRPTTDADDSGDILAVARRQVLAQGDGLSREQVLDVLRLPDDRLEDLLALAHEVRMRWCGPDVEVEGIISLKTGGCPEDCHFCSQSGLFASPVRSARLDIPSLVEAAKQTAKSGATEFCIVAAVRGPDERLMAQVAAGIEAIRDEVEINIACSLGMLTAEQVQQLAAMGVHRYNHNLETARSFFANVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETPEQRAEFAAELAQLDPDEVPLNFLNPRPGTPFGDLEVLPATEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGILGGINAVIVGNYLTTLGRPAEADLQLLDDLQMPIKALNASL
>NZ_AP022614.1|WP_085270700.1|1895395_1895635_-|hypothetical-protein
MVRDLGAPVSAGVYNVYTGESLGTSAGGAVPAAARLGLEPPRFCAECGRRMVVQVRPDGWRARCSRHGQVDSADLEAQR
>NZ_AP022614.1|WP_085270701.1|1894748_1895399_-|DUF2567-domain-containing-protein
MTAPAGPQLSGPPDPVSRSSRTRAIVVAVCGSAATGVVLGGLWAWIAPPIHAVVAMTKAGERVHDYLGDESQHFFDAPCLMLGLLTVLAVVAAVLAWQWRGHRGPGMAVGLTIGLAAAATAASATGAALVRLRYGALNFDAVPLPAGHPSVAYVYQAPPVFFSDAPAQVAITLLWPAAIGALVYAVLAAADARDDLGAHPLSGRASNTLEPHAPVS
>NZ_AP022614.1|WP_085270773.1|1893398_1894739_+|lipase
MAEFGNLAGTHGAEWIARPPHEELQRKVRPLLPADDPFYQPPLGFQHAEPGTVLRSRDVELAFLGLVPQPIRAVQLLYRSMDMNGEPEATVTTVIVPRETSPERPCPLLSYQCAIDAVSSRCFPSYALRRRAKALGSVGQFELLLISAAVAEGWAVSVPDHEGLRGLWGAPYEPGYRVLDGIRAALGSERLGLSAQAPIGLWGYSGGGLASAWAAEMSGQYAPELDIVGAVLGSPVGDLGHTFRRLNGSLLSGLPALVVAALAHIYPDLDRVIKEHANEEGRALLESLERMTTVEAVLRMARKDMGDYLDEPLENILSTPEVTYVFDNIKLGAAVPTPPVLIVQAVHDYLIDVHDIDELADAYSAGGARVTYHRDAFNEHMLLHPLSAPMTLRWLTDRFNRRPLTEHHIRTTWPTMFHPMTYVGMARLAKIAAKVVLGRKIHRRPL
>NZ_AP022614.1|WP_085270702.1|1892475_1893219_+|NUDIX-hydrolase
MAHGSTAHEVLAVVFQVRHTTEPAAGQVKKASRTAKPQLNVLLWQRAQDPQKGTWSLPGGRLRNDEDMITSVRRQLAEKVDLKELAHLEQLAVFSDPNRVPGPRVIASTFLGLVPSPATPELPADTRWHPVSSLPPMAFDHGPMVTHARTRLVAKLSYTNIGFALAPREFALSTLRDIYGAALGYQVDATNLQRVLVRRGVIRQTGTIAQSGRSGGRPAALYHFTDSRLRVTDEFAALRPPGPPGPL
>NZ_AP022614.1|WP_085270703.1|1891370_1892429_-|quinolinate-synthase-NadA
MTVVHRMDTDTDASADMVADITDSPAGYGGVAADERWAAQVRRLADLRNATLLAHNYQLPAIQDVADHVGDSLALSRIAAEAPEDTIVFCGVHFMAETAKILSPEKTVLIPDQRAGCSLADSITPDDLRAWKDEHPGAVVVSYVNTSAAVKALTDICCTSSNAVDVVASIDPDREVLFCPDQFLGAHVRRMTGRTNLHVWAGECHVHAGINGEELTEQARAHPDAELYVHPECGCATSALYLAGEGAFPADRVKILSTGGMLDAATATRARQVLVATEVGMLYQLRRAAPQVDFRAVNDRASCKYMKMITPAALLRCLVEGADEVDVDPQIAAAARRSVQRMIAIGQPGGGE
>NZ_AP022614.1|WP_085270704.1|1889790_1891374_-|L-aspartate-oxidase
MIARGWTDSADVVVIGTGVGGLAAALAAHRAGRRVVVLSKADQARGVTATHYAQGGIAVVLPGNDDSVEAHVADTLAAGAGLCDPDAVCSIVADGYRAVSDLVGAGARFDESLPGQWALTREGGHSRRRIVHAGGDATGAEVQRALDHAAATLDVRTGHVALRVLHDDGGVTGVVVGNQDGYGVISAPSVILASGGLGHLYSATTNPEGSTGDGIALALWAGVAVSDLEFIQFHPTMLYAGRAGGRRPLVTEAIRGEGAKLVDRQGNPVTAGVHPMGDLAPRDVVAGAIDARLKATGDPCVFLDARGIDGFAARFPTVTAACRAAGVDPVRQPIPVVPGAHYSCGGVVTDVCGQTELPGLYATGEVARTGMHGANRLASNSLLEGLVVGGRAGRAAAGHAAAVGGARPVPVGTVEPFTHTAPERAALQGAMSRDASVVRDAVGLGRLSDMLSGAGRRTVASRRDFEDVALAMAARAVTAAALARKESRGCHHRAEYPDTAAEQARSSVLRLAADGNAVLVEALAVVG
>NZ_AP022614.1|WP_085270695.1|1902649_1908925_+|type-I-polyketide-synthase
MIRRGPSVTIPVAVIGVACRLPGGIDSPERLWESLLSGDHLVAEIPRARWDADEYYDPEPGVPGRSVSRWGAFLDDVAGFDPEFFGIDEREAIALDPQHRLLLEASREAVEHAGVIPAAMVNSRTGVFVGLTHSDYQLMTAEPGATDGPHGRTGNTFSQASGRVAHTMGLRGPALTVDAACSSSLLAVHLACRSLGDGESDLALAGGAFVMLEPGRFLAETARGRLSPTGRCHAFDVAADGYVLGEACAMVLLKRLPDALRDGDRILAVVRGTAANQDGHCADSSTPSRTAQTEVYRAALANAGVDARSVGMVEAHGPGTRDGDPVEYACLAEVYGVESPCAVGSAKTNFGHTQAASGVLGLIKAVLSLAHGAIPENLHFTRLPDDLARVDTKLFVPQALTPWPHAGQHPRRAAVSSYGTSGTNVHAILEQAPRTSAHATHPGAAPEAPLLFALSSTSARELRRTAGRLADWVEAHDAVALPDLAYTLTRRRAHRPVRTTVVASGHRELAHAMRGIADGEAPYPAAVTQDDRGPVWVFSGQGSQWAGMGAGLLANEPVFAATVAQVEPLVARESGFSVTEAMASPQTVTGIDRVQPTLFAMQIALAETMKYYGVRPGAVIGHSLGEAAAAVVAGALSLDDGVRVICRRSRLMSTIAGAGAMAAVELPAKQVLSELTLRGVKDVVVAEVASPQSTVIGGAALAVRERVAAWEERDVPAREVAVDVASHSPQVDPILDELTDALAELNPTTPEVPFYSATSFDPREEPVCDNRYWVDNLRRTVRFAAAVRAALEDGHRVFAELAPHPLLVRAVEQTARSVDVPAAALACLRRGQDAPHGLLGFVGELHAAGAPVDFAVLYPGGRLVDAPLPTWTRRRLWLSPSGRRPSARAGSTGRAHPLLGPHVRLREQPERHVWQAEVGTAAQPWLADHRVGGAAVLPAAAYCEMALAAARLLLGETSEVRDIRFKRALPLGEDTTAGLSATSSSPGVLDFLVESDPQGGQRRRATAVLSAAADERPPAYDMPALLAAHPRRTDGAEVRNRLKQLGVQYGSAFTGLAAARTGDDATGTVLAEVALPGPIRAQEGDYGVHPALLDACLQSVEASSLVRGLGEGIVALPTSVRRLRLYGCARGAHYCYTRLTEVDDRGIEADLDVLDRHGAVLLSVRGLRCSAGTSADAHKNRVLNERLLTVEWQQRPLPEIPHCAAGAWLLISVAATADPAAALAAALSGHGAQCQILHCPPGADHSAHTQELGNRLRAARFAGVVIVHGAAHDEAPGDAAPGPGSAQHLVLLTRELLHVPGEPPRLYVVTRGAQTVLAGDRPDLGQAGLRGLIRVIGAEHPHLRATHVDVDATSDTGQLARHLLSGSDEDECAWRAGSWYTARLRAAPLRPGERRTAVAEHQVDGLRLRIREPGDLQTLELVACERLPPGPGRIEVAVAASGVNFADVLVAKGSSPGADGHPPQLGTDFAGVVTAVGPGVTGHRVGDRVGGFSEDGCWGTFVTCDARLAVTLPATLSEPQAAAITTATATAWHGLHDRAGISPGDRVLIHSATGGVGQAAIAIARAAGAEIFATAGSEERRELLRATGIEHVYDSRGTEFAEQIRRDTDGYGVDIVLNSLTGAARRAGSELLADEGHFIDIAIRGAGDDTRPALFPAHRNLTFHHVDLSLMSASHPHRVGKLLRTVYRLAADGGLPSPRHTVYPLTGAADAIRAMSAPGRSGKIVLGVPRAGRSRVTVPPERAQVFRPDGAYLVTGDLDERGLFLAEKLAEAGCGRIVLMSRAQPTRKARETIKLICAIGADVVVQCGDIAEAAAAHQLVAAATATGLPVRGVLHAAGVTEDATVANVSADIIESAWATKVYGAWNLHCALRAGEAAAPLDWFCSFSSAAALAGSPGRAAEAAANSWLDAFTRWRRGQGLAATAIAWGPWEQVGRGASPARDADVAIAPDEGAYALETLLRHDRGHTGYAPFPNAAALHALARRSRFAEAFRSTAQIRTGTTKLRAELSELPPEEWPTLLRRLVTDQISLILRCSIDPDRPLCEYGVDSLGALELRTRIENETGICVTYNDIAVTTIRGLAQLLCEKLTPA
>NZ_AP022614.1|WP_085270771.1|1908980_1909637_+|isoprenylcysteine-carboxylmethyltransferase-family-protein
MLLSGVVELVVFGLMVFLPAGTPAYWQGWVFLAVVFALATFVPGIYLLRNPVVLQRRMSGGPSAEGRTAQKVVIAGLYASLAGMVVLSGFDHRFGWSSVPTAVCLVGDVLVALGLGVVTLVVVQNNHAAATVRVEAGQQVVSTGLYGLVRHPMYTGNVIMMVGIPLALGSYWGLVFVGPGLVVLASRIRDEEKLLAEELTGYREYTQKVRYRLVPCMW
>NZ_AP022614.1|WP_139825912.1|1909645_1922206_-|amino-acid-adenylation-domain-containing-protein
MRIADVLPLTPLQQGLLFHASTAHGDDDVYAVQLQIALSGRLDRHRLRDAVQAVGVRHPNLAARFSEKFDKPVQIIPADPVVPWRYVDLGDGGPGLAGQIEQVCAEERAAVCDIARQPAFRAALIATAQDQHRLVLTNHHIVLDGWSLPILLGEIFAGYYGQRLPAPVPYRRFVTWLAGRDLDAARAAWGEVLAGFDEPTLVGPPGRPEPGPRGVASFRVAEQTTRGLGDLARSHHTTVSTVLQAAWAQLLTWLTGRHDVAFGTTVSGRPPEVLGADSMVGLFINTVPVRARVDAATTTVDLIDQLQDAYNQTLEHQHLALSELHRVTGQEQLFDTFFVYENYPLDAAALSGADGLAITDFTHREYNHYPLAIQALPGTELGLRVEYDTEVFDAARVATLIERLERVLAVMVADPGRRLSSIDVLDDGERLRLDRWGNRAGLTGPTRVPVSIPVAFGAQVARAPEAVAVTSGGVSLTYRKLNDAANRLAHLLAAHGVGAGRRVALLLPRSADAIVAMLAVLKTGATYVPIDPAVPAARMRFVLDDSAPVAAVTTAGLADRLHGCALTVIDVNDPAVDSQPSTALRAPSPDDTAYIIYTSGTTGTPKGVAIPHRNVTRLLESLDADLELAGQVWTQCHSLAFDFSVWEIWGALLYGGRLVVVPDAVVRSPEDLHALLAAEQVSVLSQTPSAFYALQSADAVQPEPQPQLKLEAVVFGGEALEPPRLRPWLDNHPGMPRLINMYGITETTVHASFREIAAGDVDGTVSPIGVPLAHLGFFVLDGWLRPVPAGVVGELYVAGAGLADGYVGRAGLSATRFVACPYGAPGARMYRTGDLVWWGPDGQLCYVGRADKQVKIRGYRIELGEVQAALAAVDGVEGAAVIAREDHPGDKRLVGYVTGTADPAAVRAALAERLPAYMVPAAVVALDALPLTVNGKLDTRALPAPEYQDSGHYRAPGSLTEEILAGIYAQVLGVERVGVDDSFFDLGGDSLSAMRLVAAVNAGLDAGLSVRTLFEAPTVARLAPRIGGDEGRLDPLVAVERPAVVPLSFSQNRLWFLDQLQGPSAIYNMAVALRLCGPLDAEALGAALADVVARHESLRTLFAAPEGIPRQLVVQAADADFGWEIVDATGWPQARVAEALGEVARHHFDLATEIPMRARLFRVGEDEHVLVAVVHHIAADGLSLAPLVHDLGVAYPSRCAGQAPGWPDLPVQYIDYTLWQRAQFGDLDDPGSLIAAQLAYWREALAGMPERLQLPTDRPYPPVADQRGASVTLEWPVELQQRIARVARAHNATSFMVVQAALAVLLAKLSASSDVAVGFPIGGRRDPALDELVGFFVNTLVLRVELAGDPTVAEVLAQVRTRSLAAYEHQDVPFEVVVDRLNPTRSLTHHPLVQVMLAWRNLPAEASDHIAVALGDLQITQLPLDTGTARVDLAFSLAERWNRGGEPTGIEGAVEFRTDVFDAASIEVLIERLRRVLVAMTADPARRLSSVDVLDQAEHAHLDDVGNRAVCNQDAAAAVSVPVMFAAQVARAPEAVAVTFAGRDMTYRQLDEAANRLAHLLSERGVGPGACVALLLERSARAVVAMLAALKAGAAYLAIDPALPAARMEFMLDDAAPRVVLTTAQLRPRLDGRGLTVIDVDDPAVDTRPATALPAPGPDDIAYLIYTSGTTGTPKGVAVAHRNLAHLAESSHPHLPPAQVWTQCHSYAFDFSVWEIWAALLGGGRLVVVPESVVGSPDDFHDLLIDERVNVLTQTPSAVIALDPHGLESVALLLGGEACPAEVVDQWAPGRVVVNAYGPTEATVYASMSAPLEPGSVGAGVAPIGAPVSTAALFVLDERLRPVPAGVVGELYVAGRGVGVGYVGRTGLTASRFVACPFGRPGARMYRTGDLVRWRPDGQLQYLGRADEQVKIRGYRIEPGEIQAVLAGLDGVEQAVVIAREDRPGDKRLVGYVTGTADPVKARAALAERLPGYMVPSAIVAVEELPLTVSGKLDRRALPAPDYQGVDSYRAPATVAEEILAGIYARVLGVQRVGADDSFFDLGGDSLSAMRLIAAVNAGLDGGLSVRALFEAPTVAQLALRLGAGGGRLEPLVAGRRPAVVPLSFAQNRLWFLGELQGPSPIYNLAVALRLRGALDADALGAALGDVVERHESLRTLFAAPGGIPRQVVAPAAYADFGWHVVDAAGFSADRLGEAIEAVTRHPFDLAAEIPLRAQLFRVADDDHVLVAVVHHIAADGASIAPLVRDLGVAYASRCAGEAPGWQRLPVQYVDYTLWQRAQLGDLSDSHSRIAAQLAYWEDALAGMPERLVLPTDRPYPPVADYRGAQVAVDWPAELQQRVARVAREHNATSFMVVQAALAVLLAKLSASSDVAVGFPIAGRRDPALDELVGFFVNTLVLRVELAGDPSVAELLAQVRTRSLAAYEHQDVPFEVLVERLNPARSLTHHPLVQVMLAWQNWQGANPGEAGDPNAGLALGDLEVTPLPVDTRTARVDLSFSLNERRSESGDPTGIGGVVEYRTDVFDAASVTALVDRLRRVLDAMTTDPQRRLSSVDVLDERERARLEGWGNRAESPQTVPVQPIPALFAAQVARTPGAAAVTFEGRSLTYAELDGAANRLANLLAGRGVGPGQRVALLFSRSIEAIVGIFAVLKTGAAYVPIDPAVPAARIDFVLDDSAPIAAVTTAEFAGRLDGRDLFVVEVDDPAVDAEPTTNALPGPAPDDIAYLIYTSGTTGTPKGVAVPHRNVARLLATLDAEMGLAQRVWSQSHSLAFDFSVWEIFGALLHGGRLVVVPDAVARSPEDFRALLVAERVSVLSQTPAAFYALQSADALQPDSGPRLALEAVVFGGEALEPLRLRPWLDKHPGLPRLINMYGITETTVHASFREIVADDVHSTVSPIGVPLAHLGFFVLDGWLRPVPAGVVGELYVTGAGLAYGYVGRAGLSATRFVACPFAEPGARMYRTGDLVAWGADGQLRYVGRADEQVKIRGYRIELGEVRAALAALDRVEQAVVIAREDRPGDKRLVGYITGQVDPAGARAALAERLPAYMVPAAVVALDALPLTPNGKLDTRALPAPEYQDTGHYRAPATPLEEILAGIYAQVLGLERVGVDESFFELGGDSILSMQVVARARAAGVVCRPRDIFVEQTVSGLARVAGVVDGADDAIDEGVGPVPATPIIWWLHSVDGPVEQFNQTMVLQAPAGVSEADAVLVVQALIDRHAMLRLRVDDDGAGGWSLEASEVGSVDARACLLAVEELSDDAVVRARSRLNPAAGIVLSALWAESTGQLALIVHHLAVDGVSWRILLEDMNIALSQHRGGQQVVLPAPGTSFARWAALLAEYAHRPDVVGQADAWRRIAATKPALPAVRPGVDTFATAGNLAALLDAETTRMLLGEVPAAFRAGVHDILLIAFALAWAQFLGTGGAPIGIDVEGHGRDEELAGPGERIDLSRTVGWFTAKYPVALRVGTLDWAQVVAGDAALGAVIKDAKEQLRGVPDPLSYGALRYLNGEVDLGESDPPIGFNYLGRLGAASDASGDMWRACRDSWSVTAAAVAIPMPLAHTVELNAGTVDSETGPQLQAGWTWAPSALEHAQVSRLSRLWFDALTGICAHVRDGGGGLTPSDVAPARLSQQQLDALCRQYAVGDVLPLTPLQQGLLFHAGAAQVNDDHVYAVQLDIALSGPLDEHRLREAVQTVATRHPNLLARFCPQFDEPVQVVPADPVAPWRYVELEAGGLDADQQVERVCAAERAAVCEIADGGPAFRAALIRTGDDRHRFVLTNHHIVLDGWSLPILLRELFACYFGQWLPAAVPYRRFFTWLAGRDRDAARAAWREAMAGFDTPTLVGPPDRLGLGRRGVEAVRIPEQTTSAVGELARSCHTTVNTVLQAAFAQLLMGWTGQRDVAFGAVISGRPAEVAGADSMVGLLINTVPVRATVGEATTTEDLLAQLQSAHNHTLEHQHLGLGEIHRVTGHKTLFDTVFVYENYPIDTAALSGVDGLAVTGLTNRDHYHYPLTIQAVPGRELDLRVQYRADVFDAATIAALVERFERLLVAMTAEPTRPLASMDLVEGGRHARFAGCAHPAALPAPEPPAGEARRDPSTWVEQILASIYAQVLGVDRVGIDESFFDLGGDSLSALRVVAAINAAIDARLGVQALVEAPTVAGLSRRLDSPAGAVAELPAVSPAADL
>NZ_AP022614.1|WP_139825911.1|1922192_1926749_-|amino-acid-adenylation-domain-containing-protein
MERDDRALPLTRGQLDIWLAQETGHSTTEWQLGVLVRFDGTIERDVLERAIRHVMQEAEPARAAIFEADDGVFQKALDYPDFEVEFHDLSDSRHPVQEARRMALAIQHTPMSPAGPLFKYALFQTWSDEFYLFGCFHHIVIDGTGITLLAHRIATVYAAIVSGAPIPPAFFGTLGDLVRCESEYEASADYLEDRAYWTEHLPPESGPHNRSPQTEADGDAYLPSATVRLDPAVLRQAHELSRAWNVPQSSFVTAACALLVRGWCAEGSEVVFDFPVSRRVRRDSKTLPGMVSGMVPLVLKVSPESTVAGFCKLVDMRVREALQHQRFPVHALERKARLRGPEQPGERVSVNFLPSKMTMDFAGVEASASFTNPGQVGDFGLIFSGAGDQLSLSTSGACGPLANFEVADLAKRLERVLAAMVADPQRRLSSIAVLDEGERLRLDGWGNRTQGIQPATRDTSIPAAFAAQAARTPESVAVTCEERSLTYAELDGAANRLANLLAGRGVGPGQRVALVLPRSAEAIVAMLAVAKTGATYVPIDPAVPAARMRFVLDDSAPVAAVTTAALADRLDGCAAAVVDVDDPALAGDPGTPPPGPAPDDVAYIIYTSGTTGAPKGVAIPHRNVTRLLATLDAGMGLAGQVWTQCHSLAFDFSVWEIWGALLFGGRVVVVPDAVVRSPEDLHALLVAEQVTILSQTPSAFYALQSADAAQPGPRAELALEAVVFGGEALEPQRLRPWLDNHPAAPRLINMYGITETTVHASFREIVADDVDTAVSPIGVPLAHLGFFVLDGWLQPVPAGVVGELYVTGAGLADGYVGRAGLSATRFVACPYGAPGARMYRTGDLVWWGADGQLRYVGRADKQVKIRGYRIELGEIQAALAALDGVEQAVVIAREDRPGDKRLVGYVTGGADPAAARTALAERLPAYMVPAAVVALDALPLTVNGKLDTRALPAPEYQDGGQYRPPADAVEEILAGIYAQVLGLERVGVDESFFELGGDSILSMQVVARARAAGVVCRPRDIFVEQTVARLARVAAVVDGAADAIDEGVGPVVPTPIISWLHSIDGPVDQFNQTVVVQAPVGTTEADVVVVLQALLDRHAMLRLRVDEGADGAWSLQVPEPGSVDARHCLHAVQVLSEEALIEARSRLNPAAGVMLSALWVASTGRLVAIVHHLAVDGVSWRILLEDLNLAWAQHRGGQQLVLPAPGTSFARWASLLAEHAHRPDVVGQAETWQRIAAMPSALPAVQPAVDTYVSAGNLAAQLDVETSRMLLGEVPAAFHAGIHEILLIAFALACAEFLGTAGAPVVIDVEGHGRQEELADDVDLSRTVGWFTTKYPVAIDVGGLSWAQVVAGDAGLGAVVKDAKEQLRALPDGLTYGVLRYLNDDVDLDGSDPPIAFNYLGRAAAGTEASGDMWEICEDGLSLIDASARLPMPLAHTVELNAATVDAYTGPYLHAGWKWAPSALNEAQVSRLSRLWFDALAGICAHVRGGGGGLTPSDIAAGLTQQQIDELQRQYADS
>NZ_AP022614.1|WP_085270694.1|1926754_1926985_-|MbtH-family-protein
MSINPFDDDEGSFFVLVNNEEQHSLWPAFADVPAGWRVAYGETDRAACLDYIEQNWTDIRPRSLRERLAAGQGLDR
>NZ_AP022614.1|WP_139825910.1|1927448_1928579_+|methyltransferase-domain-containing-protein
MPRGAATTSSARPGTACRRVCRQAVACPAATANEGRNPGEDLISRPPTGVKRRPLRSQTSTLVWTRRLSGVRDSTTPCHKTSAKQIWLRRHKMDQLSEPSAQAESAGDSPVAMSAHLADDLLSTTATGWRSFYDSLSRRLEDVGVADSSFFLNYGYLPIDSNNDSAFVIRDGTFNANSVRLVFEVVGPVDLNDRTVVEIGCGRGGNSAQVAEKFSARVTGIDMSAEAIAFCRRTHRDSIDFQVGDALNIPLADEFCDAVINVESSHSYGNLPKFLNEVRRICRPGAWFLHTDFLSTDDWDYVRARLKALGFVTETDRDITANVLASRDQAKDNWAQVYGDGNARVANFLALPGSAIYEQLRAGLLEYRILRSQLRP
>NZ_AP022614.1|WP_163670809.1|1928589_1939611_-|SDR-family-NAD(P)-dependent-oxidoreductase
MTESFAIVGYAVRVPGAPDAEAFWDVLAQGRDAVSEVPPDRWDVDEFFDPDPDAPGKIVSRRAGFIDDVTGFDAPFFGLSNRETMLIDPQHRLLLETAWQAVEHSGTAPSALANTKTGVFMGLGTHDYLGLISEQLSYDEIEAYVAIGTSSAAGAGRISYGLGLQGPAVSVDTACSSSLVAVHQACQALRLKECDLALAGGVNVMLSAKTAMTFSHAHMLAPDGKCKTFDAAADGYVRGEGCGVVIVKRLEDAIRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVITEALEAAGVAPGDVGYLEAHGTGTSLGDPIEVQAAGAVLGAGREADRPLLIGSVKTNIGHLEAAAGIAGLIKVILSLEHEVLPKHLNFQKPSPHIPWDRLAVRVVDEAVPWERGGRPRIAGVSSFGFSGTNSHVIIEEAPTAVSAAQAEPVASDDRRFSLLPLSARSPAALTQLAEQYGSWLAEHPDASLADLCFTAGAARSHFEHRAALVVNSMESARECLGALAEGRPAPGLTKGECSDKPRTAWLFPGQGSQYAGMARELFETEPVFAETMTRCAAAVAEVLEKPLLDVIFDPDGDDTLRQTAYAQPALFAVEMGLARLWQSWGFEPDVVIGHSVGQYTAACVAGVFGLEDGALLLAERGRLFGSLPAGGRMVAVFAAAERVESLTDEFPNLSVAAYNGANTVLSGPADDLERAVALLEGDGVRCDWLETSHAFHSALLEPVLDEFESYANRFEFAPPQRTLVCNRTGAALGRSAKLDGAYWRRHARQPVEFAKSVRTLADLRCTMLLEVGPQPVLTAAAMRAWPDPATAPRAIASLRRNIADHRQITEALANAYVVGHVPDFGALPPGPARKLDLPTYPFQHRQYWFREQRSKPTAQSSADTQAARTEAVRLLEDGQFEELAALLGGNGDSQQTVDVLRQLAAQHNQQRQVQSITDSRYEIRWQKSAAGTAKTSAAAKGGEGSAWLIVSDDAATVAPLADALSARGHGHRVLGLPMSDADEKRLEATLRAAVDDDPALRILHVAALDSETAPSMQSLLRMQHHVLGGTRRLFRAAAAAELRAPIWLVTRGAQRVTNADKVSPVQSSLWGFGRAAALEYPRLWGGLADLSEGGAPDGGVWSRLIDYVLAAPRAEDQVALRDQAVYVPRLVRRAGLPVTSPLGLRADATYLVTGGLGGVGLEIAGYLAAQGARHLVLTSRRSPGEAAQQHIDAMREQHGCDVRVVAADVGNPHDVARLLSTVQAELPPLAGIVHAAGEIGNTPLQTLDDAEVDRVFAGKVWGAWNLSEATAGTRLDFFLSTSSISAAWGSFGQSAYSAANAFLDGLAWRQRERGVPAISVNFGPWSAAGMADEAARAELDKRGVRPLSPADALAGMAELMVASSAKGASHGIVARIDWAGFLPLYQLAGKRAFLSELEREVPEAAAAPVAAAGTTRLVEQLTVAPVQQRKKLVVDYLRDVVAEVTRIDPAEIRDEAGFFDVGMDSLMAVELRRRVEQAVGKELPSTLAMDYPRLVDVADFLLGDVLSFGAPGTTKEAASVDSRPSRLDPAVTMRSDEPIAIVAVACRFPGAPDPEAYWELLSGGVDAIREIPEDRFDVDEYYDPDPEAPGKIYTRYGGYLESIDGFDPEFFGISPREAVWMDPQQRLMLEISWEGLERAGYSPAALRGSRTGVFVGVAANEYSQLLNASSVETIEAHFITGNALNVIAGRVAFALGLEGPAMAVDTACSASLVAVHQACQALHSGDCDMALAGGVNVLVSPASIVATSRARMLSADGRCKTFDAAANGYARSEGCGILVLKRLSDAERDGDQICAVIRGSAVNQDGASSGLTVPNGGAQQRLIAATLARAGVEGRDVDYLEAHGTGTSLGDPIEVQAAAAVYGSGRDPNRPLLIGSAKTNIGHLESAAGIAGLIKVVLSLQHEMLPRNLHFENPSPNIPWDSLPVRVVDKPIAWRANGRPRRAGTSSFGFSGTNAHVLIEEAPAPVTGAVQPEAAQPDAAGEQVGVLPLSARSPEALTELAQEYGDWLEAHPAADLADVCFTAGVGRSHFEHRAALVVDSVQGARELLAGLAENKLGPGAVRGVCGDPPKTAWLFTGQGSQYPGMARELYDSEPVFAETVDRCAEAVDGLLPRPLLEVLFDTGETGAETLRHTSFAQPALFAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAGVFSLEDGARLMAERGRLFGELPEGGRMVAVFADPQRVERAAEDFPHISVAAYNGPNTVLSGPGGDLEQIVEKLTADEIRCTWLDTSHAFHSELLEPALDEFEAYAKGFEFAVPALPLVCNRTGAVLTAENPLDAHYWRRHSRQPVQFAESVQTVAKLGCSVLMEIGPQPVLTGAALQAWPDSSAAPQAVVSLRKGTDARRQMAEALAAAYVAGHRPDFAAVHHRMHRRLELPTYPFQRRRFWPKSADIRGVDGQGVITSGILGSAKDLASGDAVYTSRWSIKTQPWLAHHVIYGTVVVPGATYAAMALAAVGTPAQVREVFFYEPIILGDKTSREVQLSVHPVEDGGGWTFQVHSRPYGDRGAEWALNADGRIADSIDDAPAPEPTESIDSACERLGRMRPQQLFDTFADMELTWGPTWSTSLKSLWSGDGEAVGDISIGDELAEQLGGEPIHPVLLDLCTGVAFPAFPAVLTENEHGDAMTDLFLPLRYGRVVLRETLPRRFYCRARWNSGGPDSETQVFDLDFVDREGRQLGEVREFTVKRAPREALLRGIGGDATRNLYTLGWEEVPPPSGNAADNGEGTWLIAGFDELAAALPNAVAVGRTTDPEAWTRLLAQAQERSAPVCGIVWRGTARPDADESNADFAARLETEIDELVTVVRTLLAQHDMKLTGGLWILTERGVATEPGEPVDPAQSALWGFGRTVITEQPMLRCRLVDYDGFDDAARSLAGLLGTPGEEPELALRQGKYLVPRLLPWGRSGHLAVPRSADYVLAPTERGAIDNLRLFETQVPAPAAGEVQIRVEAAGLNFRDVLNVLGLYPGDPGQIGGGDLAGVVTELGAGVTGLEVGQRVFGFMPGSFATRVNAPAQFLTPVPNGISSVAAATIPAGALTTRLAFDWANVGPGDRVLIHAASGGVGLAAVQMARQRGATVFATASTYKRAALRKMGVEHVYDSRSTDFADQILADTGGAGVDVVLNSLTNEGFIEATVRATAQGGRFAEIAKRDIWTREQMAAARPDISYEIIALDGCIEAEPERVGRLLAEVAESMANGELEPIAAEVYPVTEAKSAFRRMQQARHIGKIVLQMPRPLQPRGDRSYLITGGLGALGLFTAAHLAQLGAGDIVLTSRRAPDAEAQRSIDDITERYRCRIHTFTADVGDESEVATLLERIRAELPPLAGVAHLAGVLDDALLTQQSVEHFRTTLAPKAFGARYLDRLTRDDDLEFFVMYSSAASVIGSPGQANYASANALLDGLVADRRAQGLPATGINWGPWAKGGMATSHAARANLSAQGLIPLEPTAALSALDEVVANGTAQATVLKANWQRAAKGLGSSRPAMLDHVLPSDVTAARGDSELLRQLHDVPEAQRGSFLTEYLRHEVQNFLRLAQPPAATSRFLELGTDSLMAVEFSNRLLPQFGGAFTISATAVFDYPTIGSLAEYLAGQVPESALEVNGAESVAASEPTQ
>NZ_AP022614.1|WP_085269528.1|1940016_1941285_-|glycosyltransferase
MKFVLASWGSRGDVEPNLAVGRELVRRGHDVCMAVPPDLVGFTEAAGVPAVGFGPEARSILDAHREFWTCFFSHPWRIRKLITSRLDIAGPLLRGWQEMSTTLTSLADGADLIFTGINFEDAAANVAEHFDIPLATLHYFPLRPNGQTLRFLPAPLARQAVAAFWWVSWRGMKKAENAQRLELGLPPASGSAPRRITERGSLEIQAYDEACFPGLAREWAARAGQRPFVGTLTLDLQTDADEEVASWIAAGTPPVFFGFGSIPVESPADTIAMIAAACSRLGERALVGAAGTDFGDVPHFDHVKVVGTMNYATVFPACRAVVHHGGSSTTPIAMRAGVPQLILFWDLVHAVYGAAVKRLKVGTARRFSSATEESLVADLSTILAPDYAERAGALATHITEPAKSAAAATDLLENFARRRPAG
>NZ_AP022614.1|WP_085269531.1|1941741_1942464_+|rhamnosyl-O-methyltransferase
MFESASTPWDFFKKTIAIPSLARHFYQPTGSECEEYHKWFYNTGVFNHMTWMGVMCQKSASDMWNYQEILFELKPSLVIEFGTNQGGSALFFASVMRQIGAPFKVLSVDVYHGPLEPRARRDSDILFVESRSTVPAVAQHIQRLKEEYPGRIFAILDSDHSMNHVLAEMKLLRPLLSAGDYLIVEDSNMNGHPVLPGWGPGPYEAIEAYEREFPNDYKHDVARENKFGWTQAPNGYLIRN
>NZ_AP022614.1|WP_085269530.1|1942497_1943232_-|class-I-SAM-dependent-methyltransferase
MLADAWPGVNRIRAVQRALAGRPDPVYLEIGVSRGQAFQRIAADVKIAVDPAFKLSERTRQLSDAKGRETHYFETTSDAFFENETAFLERHPIDVALIDGLHTYEQVVRDVEYTLRYLRDDGVIFLHDCNPPFALAGRRAESWDEFVAQQSGPLVIGIWNGDVWKAIVQLRSTRPDLLVGVLKCDQGVGFVRKGSPESTLPYSVEQVEALTYADLKADRERLLNLKPTRYLNEFLAAGAGSPPR

Crispr_ID: NZ_AP022614_3

• CRISPR_ID: NZ_AP022614_3
• CRISPR_location: 1901414-1901611
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NZ_AP022614_3

Consensus_repeat	Method
CCGGCCCCGCCGTTGCCGCCGTTACCG	CRISPRCasFinder

spacers of NZ_AP022614_3

>3.1|1901441|18|NZ_AP022614|CRISPRCasFinder
CCGGCACCGCCGGTGCCG
>3.2|1901486|39|NZ_AP022614|CRISPRCasFinder
GCGTTACCGCCGTTGCCGCCGGGCTTGCCGGCGACGGTC
>3.3|1901552|33|NZ_AP022614|CRISPRCasFinder
ACCAGGAGCCCACCGTTGCCACCGTTCGGGCTG

CRISPR arrays and Neighbor proteins around NZ_AP022614_3

CRISPR arrays

The CRISPR arrays of NZ_AP022614_3

>merge|NZ_AP022614|3|1901414-1901611|CRISPRCasFinder
GCGTTGCCGCCGTTGCCGCCGGCCGCGCCGGCACCGCCGGTGCCGCCCGCGCCGCCGTTGCCGAGGAAGCCCGCGTTACCGCCGTTGCCGCCGGGCTTGCCGGCGACGGTCGAGTTCCAGCCGTTGCCGCCGTTGCCCACCAGGAGCCCACCGTTGCCACCGTTCGGGCTGGCCGCCGTCCCGTTGGCGCCGTTGCCG

>NZ_AP022614|3|3|1901414-1901611|CRISPRCasFinder
GCGTTGCCGCCGTTGCCGCCGGCCGCG	CCGGCACCGCCGGTGCCG
CCCGCGCCGCCGTTGCCGAGGAAGCCC	GCGTTACCGCCGTTGCCGCCGGGCTTGCCGGCGACGGTC
GAGTTCCAGCCGTTGCCGCCGTTGCCC	ACCAGGAGCCCACCGTTGCCACCGTTCGGGCTG
GCCGCCGTCCCGTTGGCGCCGTTGCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP022614.1|WP_085269530.1|1942497_1943232_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379276
NZ_AP022614.1|WP_139825911.1|1922192_1926749_-|amino-acid-adenylation-domain-containing-protein	unknown	unknown	gnl|CDD|237108
NZ_AP022614.1|WP_139825910.1|1927448_1928579_+|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|379312
NZ_AP022614.1|WP_085270773.1|1893398_1894739_+|lipase	unknown	unknown	gnl|CDD|367570
NZ_AP022614.1|WP_085270700.1|1895395_1895635_-|hypothetical-protein	unknown	unknown	unknown
NZ_AP022614.1|WP_139825912.1|1909645_1922206_-|amino-acid-adenylation-domain-containing-protein	unknown	unknown	gnl|CDD|237108
NZ_AP022614.1|WP_085270772.1|1895654_1896692_-|biotin-synthase-BioB	unknown	unknown	gnl|CDD|235755
NZ_AP022614.1|WP_163670809.1|1928589_1939611_-|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|225858
NZ_AP022614.1|WP_085270697.1|1898009_1899158_-|8-amino-7-oxononanoate-synthase	unknown	unknown	gnl|CDD|235655
NZ_AP022614.1|WP_085269528.1|1940016_1941285_-|glycosyltransferase	unknown	unknown	gnl|CDD|224732
NZ_AP022614.1|WP_085270701.1|1894748_1895399_-|DUF2567-domain-containing-protein	unknown	unknown	gnl|CDD|371258
NZ_AP022614.1|WP_085270698.1|1897332_1898013_-|ATP-dependent-dethiobiotin-synthetase-BioD	unknown	unknown	gnl|CDD|234625
NZ_AP022614.1|WP_085270704.1|1889790_1891374_-|L-aspartate-oxidase	unknown	unknown	gnl|CDD|236102
NZ_AP022614.1|WP_085270702.1|1892475_1893219_+|NUDIX-hydrolase	unknown	unknown	gnl|CDD|223979
NZ_AP022614.1|WP_085270771.1|1908980_1909637_+|isoprenylcysteine-carboxylmethyltransferase-family-protein	unknown	unknown	gnl|CDD|224931
NZ_AP022614.1|WP_085270694.1|1926754_1926985_-|MbtH-family-protein	unknown	unknown	gnl|CDD|377081
NZ_AP022614.1|WP_085270699.1|1896826_1897333_-|2'-5'-RNA-ligase-family-protein	unknown	unknown	gnl|CDD|379265
NZ_AP022614.1|WP_085269531.1|1941741_1942464_+|rhamnosyl-O-methyltransferase	unknown	unknown	gnl|CDD|226041
NZ_AP022614.1|WP_085270695.1|1902649_1908925_+|type-I-polyketide-synthase	unknown	unknown	gnl|CDD|225858
NZ_AP022614.1|WP_085270703.1|1891370_1892429_-|quinolinate-synthase-NadA	unknown	unknown	gnl|CDD|236489

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP022614.1|WP_139825911.1|1922192_1926749_-|amino-acid-adenylation-domain-containing-protein	gnl|CDD|237108	PRK12467, PRK12467, peptide synthase; Provisional.	0
NZ_AP022614.1|WP_139825910.1|1927448_1928579_+|methyltransferase-domain-containing-protein	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	2.73375e-22
NZ_AP022614.1|WP_085270773.1|1893398_1894739_+|lipase	gnl|CDD|367570	pfam03583, LIP, Secretory lipase. These lipases are expressed and secreted during the infection cycle of these pathogens. In particular, C. albicans has a large number of different lipases, possibly reflecting broad lipolytic activity, which may contribute to the persistence and virulence of C. albicans in human tissue.	8.65547e-109
NZ_AP022614.1|WP_085270704.1|1889790_1891374_-|L-aspartate-oxidase	gnl|CDD|236102	PRK07804, PRK07804, L-aspartate oxidase; Provisional.	0
NZ_AP022614.1|WP_139825912.1|1909645_1922206_-|amino-acid-adenylation-domain-containing-protein	gnl|CDD|237108	PRK12467, PRK12467, peptide synthase; Provisional.	0
NZ_AP022614.1|WP_085270772.1|1895654_1896692_-|biotin-synthase-BioB	gnl|CDD|235755	PRK06256, PRK06256, biotin synthase; Validated.	0
NZ_AP022614.1|WP_163670809.1|1928589_1939611_-|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|225858	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	0
NZ_AP022614.1|WP_085270697.1|1898009_1899158_-|8-amino-7-oxononanoate-synthase	gnl|CDD|235655	PRK05958, PRK05958, 8-amino-7-oxononanoate synthase; Reviewed.	1.47739e-175
NZ_AP022614.1|WP_085269528.1|1940016_1941285_-|glycosyltransferase	gnl|CDD|224732	COG1819, COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms].	3.25589e-62
NZ_AP022614.1|WP_085270701.1|1894748_1895399_-|DUF2567-domain-containing-protein	gnl|CDD|371258	pfam10821, DUF2567, Protein of unknown function (DUF2567). This is a bacterial family of proteins with unknown function.	2.12756e-64
NZ_AP022614.1|WP_085270698.1|1897332_1898013_-|ATP-dependent-dethiobiotin-synthetase-BioD	gnl|CDD|234625	PRK00090, bioD, ATP-dependent dethiobiotin synthetase BioD.	4.29421e-63
NZ_AP022614.1|WP_085270694.1|1926754_1926985_-|MbtH-family-protein	gnl|CDD|377081	pfam03621, MbtH, MbtH-like protein. This domain is found in the MbtH protein as well as at the N-terminus of the antibiotic synthesis protein NIKP1. MbtH and its homologs were first noted in gene clusters involved in non-ribosomal peptides and other secondary metabolites by Quadri et al. This domain is about 70 amino acids long and contains 3 fully conserved tryptophan residues. The structure of the PA2412 protein shows it adopts a beta-beta-beta-alpha-alpha topology with the short C-terminal helix forming the tip of an overall arrowhead shape. MbtH proteins have been shown to be required for the synthesis of antibiotics, siderophores and glycopeptidolipids.	1.54967e-31
NZ_AP022614.1|WP_085270702.1|1892475_1893219_+|NUDIX-hydrolase	gnl|CDD|223979	COG1051, COG1051, ADP-ribose pyrophosphatase [Nucleotide transport and metabolism].	3.39243e-24
NZ_AP022614.1|WP_085270771.1|1908980_1909637_+|isoprenylcysteine-carboxylmethyltransferase-family-protein	gnl|CDD|224931	COG2020, STE14, Putative protein-S-isoprenylcysteine methyltransferase [Posttranslational modification, protein turnover, chaperones].	1.22517e-24
NZ_AP022614.1|WP_085269530.1|1942497_1943232_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|379276	pfam13578, Methyltransf_24, Methyltransferase domain. This family appears to be a methyltransferase domain.	2.65255e-16
NZ_AP022614.1|WP_085270699.1|1896826_1897333_-|2'-5'-RNA-ligase-family-protein	gnl|CDD|379265	pfam13563, 2_5_RNA_ligase2, 2'-5' RNA ligase superfamily. This family contains proteins related to pfam02834. These proteins are likely to be enzymes, but they may not share the RNA ligase activity.	8.60095e-05
NZ_AP022614.1|WP_085269531.1|1941741_1942464_+|rhamnosyl-O-methyltransferase	gnl|CDD|226041	COG3510, CmcI, Cephalosporin hydroxylase [Defense mechanisms].	7.07888e-105
NZ_AP022614.1|WP_085270695.1|1902649_1908925_+|type-I-polyketide-synthase	gnl|CDD|225858	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	0
NZ_AP022614.1|WP_085270703.1|1891370_1892429_-|quinolinate-synthase-NadA	gnl|CDD|236489	PRK09375, PRK09375, quinolinate synthase NadA.	6.70176e-170

Protein sequences

>NZ_AP022614.1|WP_085270697.1|1898009_1899158_-|8-amino-7-oxononanoate-synthase
MKAPIDASPLAWLSQRETQRREAGLRRTLRPRPAVATELDLASNDYLGLSQHPDVIEGGVAALRIWGAGSTGSRLVTGDTELHQQFESDLADFVGAPSALLFSSGYAANLGAVVGLSGRGSLLVSDALSHASLVDACRLSRARVAVTPHRDVDAVEAALRSRDEERAVVITESVFSADGALAPVRELHQACRRHGALLVVDEAHGLGVRGGGRGLLHELGLAGAPDVVMTTTLSKALGSQGGAVLGPAAVRAHLIDAARTFIFDTGLAPAAVGAALAALAVLRAEPWRPDAVLRHARDLARICGVTAVPQSAVVSVILGEPEVAVAAAAACLDAGVRVGCFRPPTVPVGTSRLRLTARASLSDAELDLARQVLTDVLSFPRR
>NZ_AP022614.1|WP_085270698.1|1897332_1898013_-|ATP-dependent-dethiobiotin-synthetase-BioD
MTVLVVTGTGTGVGKTVVTAALACHARLAGVDVAVCKPVQTGTGAGDDDLAEVARLSGVGELAGLARYPQPLAPAAAAERAGMALPTRDQLLRLISGLDRPGRLTLVEGAGGLLVELAGGGVTLRDLAVDLGAAVLVVAAAGLGTLNHTALTLEALVSHDVSCAGVVIGSWPRRVGTVETSNREALARMAAVRAALPAGAASMDGGEFADMSAAAFDRDWVTSLVG
>NZ_AP022614.1|WP_085270699.1|1896826_1897333_-|2'-5'-RNA-ligase-family-protein
MVHSIELLFDAGTEAALRQIWDDLAGADIAGRPPPGRPHVTLVVAERIAADVDAALRPLTGLLPLRCTVGASLLLGRSNAILARLIVPTVAMLDLHAQVYHRCVEHLLPAPAPHSLPGQWTPHVTLARRVEGPALSAALRVAGRPPQLQGGFAGLRRWDGDAKVDYLL
>NZ_AP022614.1|WP_085270772.1|1895654_1896692_-|biotin-synthase-BioB
MTQAATRPTTDADDSGDILAVARRQVLAQGDGLSREQVLDVLRLPDDRLEDLLALAHEVRMRWCGPDVEVEGIISLKTGGCPEDCHFCSQSGLFASPVRSARLDIPSLVEAAKQTAKSGATEFCIVAAVRGPDERLMAQVAAGIEAIRDEVEINIACSLGMLTAEQVQQLAAMGVHRYNHNLETARSFFANVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETPEQRAEFAAELAQLDPDEVPLNFLNPRPGTPFGDLEVLPATEALKSVAAFRLALPRTILRFAGGREITLGDLGAKQGILGGINAVIVGNYLTTLGRPAEADLQLLDDLQMPIKALNASL
>NZ_AP022614.1|WP_085270700.1|1895395_1895635_-|hypothetical-protein
MVRDLGAPVSAGVYNVYTGESLGTSAGGAVPAAARLGLEPPRFCAECGRRMVVQVRPDGWRARCSRHGQVDSADLEAQR
>NZ_AP022614.1|WP_085270701.1|1894748_1895399_-|DUF2567-domain-containing-protein
MTAPAGPQLSGPPDPVSRSSRTRAIVVAVCGSAATGVVLGGLWAWIAPPIHAVVAMTKAGERVHDYLGDESQHFFDAPCLMLGLLTVLAVVAAVLAWQWRGHRGPGMAVGLTIGLAAAATAASATGAALVRLRYGALNFDAVPLPAGHPSVAYVYQAPPVFFSDAPAQVAITLLWPAAIGALVYAVLAAADARDDLGAHPLSGRASNTLEPHAPVS
>NZ_AP022614.1|WP_085270773.1|1893398_1894739_+|lipase
MAEFGNLAGTHGAEWIARPPHEELQRKVRPLLPADDPFYQPPLGFQHAEPGTVLRSRDVELAFLGLVPQPIRAVQLLYRSMDMNGEPEATVTTVIVPRETSPERPCPLLSYQCAIDAVSSRCFPSYALRRRAKALGSVGQFELLLISAAVAEGWAVSVPDHEGLRGLWGAPYEPGYRVLDGIRAALGSERLGLSAQAPIGLWGYSGGGLASAWAAEMSGQYAPELDIVGAVLGSPVGDLGHTFRRLNGSLLSGLPALVVAALAHIYPDLDRVIKEHANEEGRALLESLERMTTVEAVLRMARKDMGDYLDEPLENILSTPEVTYVFDNIKLGAAVPTPPVLIVQAVHDYLIDVHDIDELADAYSAGGARVTYHRDAFNEHMLLHPLSAPMTLRWLTDRFNRRPLTEHHIRTTWPTMFHPMTYVGMARLAKIAAKVVLGRKIHRRPL
>NZ_AP022614.1|WP_085270702.1|1892475_1893219_+|NUDIX-hydrolase
MAHGSTAHEVLAVVFQVRHTTEPAAGQVKKASRTAKPQLNVLLWQRAQDPQKGTWSLPGGRLRNDEDMITSVRRQLAEKVDLKELAHLEQLAVFSDPNRVPGPRVIASTFLGLVPSPATPELPADTRWHPVSSLPPMAFDHGPMVTHARTRLVAKLSYTNIGFALAPREFALSTLRDIYGAALGYQVDATNLQRVLVRRGVIRQTGTIAQSGRSGGRPAALYHFTDSRLRVTDEFAALRPPGPPGPL
>NZ_AP022614.1|WP_085270703.1|1891370_1892429_-|quinolinate-synthase-NadA
MTVVHRMDTDTDASADMVADITDSPAGYGGVAADERWAAQVRRLADLRNATLLAHNYQLPAIQDVADHVGDSLALSRIAAEAPEDTIVFCGVHFMAETAKILSPEKTVLIPDQRAGCSLADSITPDDLRAWKDEHPGAVVVSYVNTSAAVKALTDICCTSSNAVDVVASIDPDREVLFCPDQFLGAHVRRMTGRTNLHVWAGECHVHAGINGEELTEQARAHPDAELYVHPECGCATSALYLAGEGAFPADRVKILSTGGMLDAATATRARQVLVATEVGMLYQLRRAAPQVDFRAVNDRASCKYMKMITPAALLRCLVEGADEVDVDPQIAAAARRSVQRMIAIGQPGGGE
>NZ_AP022614.1|WP_085270704.1|1889790_1891374_-|L-aspartate-oxidase
MIARGWTDSADVVVIGTGVGGLAAALAAHRAGRRVVVLSKADQARGVTATHYAQGGIAVVLPGNDDSVEAHVADTLAAGAGLCDPDAVCSIVADGYRAVSDLVGAGARFDESLPGQWALTREGGHSRRRIVHAGGDATGAEVQRALDHAAATLDVRTGHVALRVLHDDGGVTGVVVGNQDGYGVISAPSVILASGGLGHLYSATTNPEGSTGDGIALALWAGVAVSDLEFIQFHPTMLYAGRAGGRRPLVTEAIRGEGAKLVDRQGNPVTAGVHPMGDLAPRDVVAGAIDARLKATGDPCVFLDARGIDGFAARFPTVTAACRAAGVDPVRQPIPVVPGAHYSCGGVVTDVCGQTELPGLYATGEVARTGMHGANRLASNSLLEGLVVGGRAGRAAAGHAAAVGGARPVPVGTVEPFTHTAPERAALQGAMSRDASVVRDAVGLGRLSDMLSGAGRRTVASRRDFEDVALAMAARAVTAAALARKESRGCHHRAEYPDTAAEQARSSVLRLAADGNAVLVEALAVVG
>NZ_AP022614.1|WP_085270695.1|1902649_1908925_+|type-I-polyketide-synthase
MIRRGPSVTIPVAVIGVACRLPGGIDSPERLWESLLSGDHLVAEIPRARWDADEYYDPEPGVPGRSVSRWGAFLDDVAGFDPEFFGIDEREAIALDPQHRLLLEASREAVEHAGVIPAAMVNSRTGVFVGLTHSDYQLMTAEPGATDGPHGRTGNTFSQASGRVAHTMGLRGPALTVDAACSSSLLAVHLACRSLGDGESDLALAGGAFVMLEPGRFLAETARGRLSPTGRCHAFDVAADGYVLGEACAMVLLKRLPDALRDGDRILAVVRGTAANQDGHCADSSTPSRTAQTEVYRAALANAGVDARSVGMVEAHGPGTRDGDPVEYACLAEVYGVESPCAVGSAKTNFGHTQAASGVLGLIKAVLSLAHGAIPENLHFTRLPDDLARVDTKLFVPQALTPWPHAGQHPRRAAVSSYGTSGTNVHAILEQAPRTSAHATHPGAAPEAPLLFALSSTSARELRRTAGRLADWVEAHDAVALPDLAYTLTRRRAHRPVRTTVVASGHRELAHAMRGIADGEAPYPAAVTQDDRGPVWVFSGQGSQWAGMGAGLLANEPVFAATVAQVEPLVARESGFSVTEAMASPQTVTGIDRVQPTLFAMQIALAETMKYYGVRPGAVIGHSLGEAAAAVVAGALSLDDGVRVICRRSRLMSTIAGAGAMAAVELPAKQVLSELTLRGVKDVVVAEVASPQSTVIGGAALAVRERVAAWEERDVPAREVAVDVASHSPQVDPILDELTDALAELNPTTPEVPFYSATSFDPREEPVCDNRYWVDNLRRTVRFAAAVRAALEDGHRVFAELAPHPLLVRAVEQTARSVDVPAAALACLRRGQDAPHGLLGFVGELHAAGAPVDFAVLYPGGRLVDAPLPTWTRRRLWLSPSGRRPSARAGSTGRAHPLLGPHVRLREQPERHVWQAEVGTAAQPWLADHRVGGAAVLPAAAYCEMALAAARLLLGETSEVRDIRFKRALPLGEDTTAGLSATSSSPGVLDFLVESDPQGGQRRRATAVLSAAADERPPAYDMPALLAAHPRRTDGAEVRNRLKQLGVQYGSAFTGLAAARTGDDATGTVLAEVALPGPIRAQEGDYGVHPALLDACLQSVEASSLVRGLGEGIVALPTSVRRLRLYGCARGAHYCYTRLTEVDDRGIEADLDVLDRHGAVLLSVRGLRCSAGTSADAHKNRVLNERLLTVEWQQRPLPEIPHCAAGAWLLISVAATADPAAALAAALSGHGAQCQILHCPPGADHSAHTQELGNRLRAARFAGVVIVHGAAHDEAPGDAAPGPGSAQHLVLLTRELLHVPGEPPRLYVVTRGAQTVLAGDRPDLGQAGLRGLIRVIGAEHPHLRATHVDVDATSDTGQLARHLLSGSDEDECAWRAGSWYTARLRAAPLRPGERRTAVAEHQVDGLRLRIREPGDLQTLELVACERLPPGPGRIEVAVAASGVNFADVLVAKGSSPGADGHPPQLGTDFAGVVTAVGPGVTGHRVGDRVGGFSEDGCWGTFVTCDARLAVTLPATLSEPQAAAITTATATAWHGLHDRAGISPGDRVLIHSATGGVGQAAIAIARAAGAEIFATAGSEERRELLRATGIEHVYDSRGTEFAEQIRRDTDGYGVDIVLNSLTGAARRAGSELLADEGHFIDIAIRGAGDDTRPALFPAHRNLTFHHVDLSLMSASHPHRVGKLLRTVYRLAADGGLPSPRHTVYPLTGAADAIRAMSAPGRSGKIVLGVPRAGRSRVTVPPERAQVFRPDGAYLVTGDLDERGLFLAEKLAEAGCGRIVLMSRAQPTRKARETIKLICAIGADVVVQCGDIAEAAAAHQLVAAATATGLPVRGVLHAAGVTEDATVANVSADIIESAWATKVYGAWNLHCALRAGEAAAPLDWFCSFSSAAALAGSPGRAAEAAANSWLDAFTRWRRGQGLAATAIAWGPWEQVGRGASPARDADVAIAPDEGAYALETLLRHDRGHTGYAPFPNAAALHALARRSRFAEAFRSTAQIRTGTTKLRAELSELPPEEWPTLLRRLVTDQISLILRCSIDPDRPLCEYGVDSLGALELRTRIENETGICVTYNDIAVTTIRGLAQLLCEKLTPA
>NZ_AP022614.1|WP_085270771.1|1908980_1909637_+|isoprenylcysteine-carboxylmethyltransferase-family-protein
MLLSGVVELVVFGLMVFLPAGTPAYWQGWVFLAVVFALATFVPGIYLLRNPVVLQRRMSGGPSAEGRTAQKVVIAGLYASLAGMVVLSGFDHRFGWSSVPTAVCLVGDVLVALGLGVVTLVVVQNNHAAATVRVEAGQQVVSTGLYGLVRHPMYTGNVIMMVGIPLALGSYWGLVFVGPGLVVLASRIRDEEKLLAEELTGYREYTQKVRYRLVPCMW
>NZ_AP022614.1|WP_139825912.1|1909645_1922206_-|amino-acid-adenylation-domain-containing-protein
MRIADVLPLTPLQQGLLFHASTAHGDDDVYAVQLQIALSGRLDRHRLRDAVQAVGVRHPNLAARFSEKFDKPVQIIPADPVVPWRYVDLGDGGPGLAGQIEQVCAEERAAVCDIARQPAFRAALIATAQDQHRLVLTNHHIVLDGWSLPILLGEIFAGYYGQRLPAPVPYRRFVTWLAGRDLDAARAAWGEVLAGFDEPTLVGPPGRPEPGPRGVASFRVAEQTTRGLGDLARSHHTTVSTVLQAAWAQLLTWLTGRHDVAFGTTVSGRPPEVLGADSMVGLFINTVPVRARVDAATTTVDLIDQLQDAYNQTLEHQHLALSELHRVTGQEQLFDTFFVYENYPLDAAALSGADGLAITDFTHREYNHYPLAIQALPGTELGLRVEYDTEVFDAARVATLIERLERVLAVMVADPGRRLSSIDVLDDGERLRLDRWGNRAGLTGPTRVPVSIPVAFGAQVARAPEAVAVTSGGVSLTYRKLNDAANRLAHLLAAHGVGAGRRVALLLPRSADAIVAMLAVLKTGATYVPIDPAVPAARMRFVLDDSAPVAAVTTAGLADRLHGCALTVIDVNDPAVDSQPSTALRAPSPDDTAYIIYTSGTTGTPKGVAIPHRNVTRLLESLDADLELAGQVWTQCHSLAFDFSVWEIWGALLYGGRLVVVPDAVVRSPEDLHALLAAEQVSVLSQTPSAFYALQSADAVQPEPQPQLKLEAVVFGGEALEPPRLRPWLDNHPGMPRLINMYGITETTVHASFREIAAGDVDGTVSPIGVPLAHLGFFVLDGWLRPVPAGVVGELYVAGAGLADGYVGRAGLSATRFVACPYGAPGARMYRTGDLVWWGPDGQLCYVGRADKQVKIRGYRIELGEVQAALAAVDGVEGAAVIAREDHPGDKRLVGYVTGTADPAAVRAALAERLPAYMVPAAVVALDALPLTVNGKLDTRALPAPEYQDSGHYRAPGSLTEEILAGIYAQVLGVERVGVDDSFFDLGGDSLSAMRLVAAVNAGLDAGLSVRTLFEAPTVARLAPRIGGDEGRLDPLVAVERPAVVPLSFSQNRLWFLDQLQGPSAIYNMAVALRLCGPLDAEALGAALADVVARHESLRTLFAAPEGIPRQLVVQAADADFGWEIVDATGWPQARVAEALGEVARHHFDLATEIPMRARLFRVGEDEHVLVAVVHHIAADGLSLAPLVHDLGVAYPSRCAGQAPGWPDLPVQYIDYTLWQRAQFGDLDDPGSLIAAQLAYWREALAGMPERLQLPTDRPYPPVADQRGASVTLEWPVELQQRIARVARAHNATSFMVVQAALAVLLAKLSASSDVAVGFPIGGRRDPALDELVGFFVNTLVLRVELAGDPTVAEVLAQVRTRSLAAYEHQDVPFEVVVDRLNPTRSLTHHPLVQVMLAWRNLPAEASDHIAVALGDLQITQLPLDTGTARVDLAFSLAERWNRGGEPTGIEGAVEFRTDVFDAASIEVLIERLRRVLVAMTADPARRLSSVDVLDQAEHAHLDDVGNRAVCNQDAAAAVSVPVMFAAQVARAPEAVAVTFAGRDMTYRQLDEAANRLAHLLSERGVGPGACVALLLERSARAVVAMLAALKAGAAYLAIDPALPAARMEFMLDDAAPRVVLTTAQLRPRLDGRGLTVIDVDDPAVDTRPATALPAPGPDDIAYLIYTSGTTGTPKGVAVAHRNLAHLAESSHPHLPPAQVWTQCHSYAFDFSVWEIWAALLGGGRLVVVPESVVGSPDDFHDLLIDERVNVLTQTPSAVIALDPHGLESVALLLGGEACPAEVVDQWAPGRVVVNAYGPTEATVYASMSAPLEPGSVGAGVAPIGAPVSTAALFVLDERLRPVPAGVVGELYVAGRGVGVGYVGRTGLTASRFVACPFGRPGARMYRTGDLVRWRPDGQLQYLGRADEQVKIRGYRIEPGEIQAVLAGLDGVEQAVVIAREDRPGDKRLVGYVTGTADPVKARAALAERLPGYMVPSAIVAVEELPLTVSGKLDRRALPAPDYQGVDSYRAPATVAEEILAGIYARVLGVQRVGADDSFFDLGGDSLSAMRLIAAVNAGLDGGLSVRALFEAPTVAQLALRLGAGGGRLEPLVAGRRPAVVPLSFAQNRLWFLGELQGPSPIYNLAVALRLRGALDADALGAALGDVVERHESLRTLFAAPGGIPRQVVAPAAYADFGWHVVDAAGFSADRLGEAIEAVTRHPFDLAAEIPLRAQLFRVADDDHVLVAVVHHIAADGASIAPLVRDLGVAYASRCAGEAPGWQRLPVQYVDYTLWQRAQLGDLSDSHSRIAAQLAYWEDALAGMPERLVLPTDRPYPPVADYRGAQVAVDWPAELQQRVARVAREHNATSFMVVQAALAVLLAKLSASSDVAVGFPIAGRRDPALDELVGFFVNTLVLRVELAGDPSVAELLAQVRTRSLAAYEHQDVPFEVLVERLNPARSLTHHPLVQVMLAWQNWQGANPGEAGDPNAGLALGDLEVTPLPVDTRTARVDLSFSLNERRSESGDPTGIGGVVEYRTDVFDAASVTALVDRLRRVLDAMTTDPQRRLSSVDVLDERERARLEGWGNRAESPQTVPVQPIPALFAAQVARTPGAAAVTFEGRSLTYAELDGAANRLANLLAGRGVGPGQRVALLFSRSIEAIVGIFAVLKTGAAYVPIDPAVPAARIDFVLDDSAPIAAVTTAEFAGRLDGRDLFVVEVDDPAVDAEPTTNALPGPAPDDIAYLIYTSGTTGTPKGVAVPHRNVARLLATLDAEMGLAQRVWSQSHSLAFDFSVWEIFGALLHGGRLVVVPDAVARSPEDFRALLVAERVSVLSQTPAAFYALQSADALQPDSGPRLALEAVVFGGEALEPLRLRPWLDKHPGLPRLINMYGITETTVHASFREIVADDVHSTVSPIGVPLAHLGFFVLDGWLRPVPAGVVGELYVTGAGLAYGYVGRAGLSATRFVACPFAEPGARMYRTGDLVAWGADGQLRYVGRADEQVKIRGYRIELGEVRAALAALDRVEQAVVIAREDRPGDKRLVGYITGQVDPAGARAALAERLPAYMVPAAVVALDALPLTPNGKLDTRALPAPEYQDTGHYRAPATPLEEILAGIYAQVLGLERVGVDESFFELGGDSILSMQVVARARAAGVVCRPRDIFVEQTVSGLARVAGVVDGADDAIDEGVGPVPATPIIWWLHSVDGPVEQFNQTMVLQAPAGVSEADAVLVVQALIDRHAMLRLRVDDDGAGGWSLEASEVGSVDARACLLAVEELSDDAVVRARSRLNPAAGIVLSALWAESTGQLALIVHHLAVDGVSWRILLEDMNIALSQHRGGQQVVLPAPGTSFARWAALLAEYAHRPDVVGQADAWRRIAATKPALPAVRPGVDTFATAGNLAALLDAETTRMLLGEVPAAFRAGVHDILLIAFALAWAQFLGTGGAPIGIDVEGHGRDEELAGPGERIDLSRTVGWFTAKYPVALRVGTLDWAQVVAGDAALGAVIKDAKEQLRGVPDPLSYGALRYLNGEVDLGESDPPIGFNYLGRLGAASDASGDMWRACRDSWSVTAAAVAIPMPLAHTVELNAGTVDSETGPQLQAGWTWAPSALEHAQVSRLSRLWFDALTGICAHVRDGGGGLTPSDVAPARLSQQQLDALCRQYAVGDVLPLTPLQQGLLFHAGAAQVNDDHVYAVQLDIALSGPLDEHRLREAVQTVATRHPNLLARFCPQFDEPVQVVPADPVAPWRYVELEAGGLDADQQVERVCAAERAAVCEIADGGPAFRAALIRTGDDRHRFVLTNHHIVLDGWSLPILLRELFACYFGQWLPAAVPYRRFFTWLAGRDRDAARAAWREAMAGFDTPTLVGPPDRLGLGRRGVEAVRIPEQTTSAVGELARSCHTTVNTVLQAAFAQLLMGWTGQRDVAFGAVISGRPAEVAGADSMVGLLINTVPVRATVGEATTTEDLLAQLQSAHNHTLEHQHLGLGEIHRVTGHKTLFDTVFVYENYPIDTAALSGVDGLAVTGLTNRDHYHYPLTIQAVPGRELDLRVQYRADVFDAATIAALVERFERLLVAMTAEPTRPLASMDLVEGGRHARFAGCAHPAALPAPEPPAGEARRDPSTWVEQILASIYAQVLGVDRVGIDESFFDLGGDSLSALRVVAAINAAIDARLGVQALVEAPTVAGLSRRLDSPAGAVAELPAVSPAADL
>NZ_AP022614.1|WP_139825911.1|1922192_1926749_-|amino-acid-adenylation-domain-containing-protein
MERDDRALPLTRGQLDIWLAQETGHSTTEWQLGVLVRFDGTIERDVLERAIRHVMQEAEPARAAIFEADDGVFQKALDYPDFEVEFHDLSDSRHPVQEARRMALAIQHTPMSPAGPLFKYALFQTWSDEFYLFGCFHHIVIDGTGITLLAHRIATVYAAIVSGAPIPPAFFGTLGDLVRCESEYEASADYLEDRAYWTEHLPPESGPHNRSPQTEADGDAYLPSATVRLDPAVLRQAHELSRAWNVPQSSFVTAACALLVRGWCAEGSEVVFDFPVSRRVRRDSKTLPGMVSGMVPLVLKVSPESTVAGFCKLVDMRVREALQHQRFPVHALERKARLRGPEQPGERVSVNFLPSKMTMDFAGVEASASFTNPGQVGDFGLIFSGAGDQLSLSTSGACGPLANFEVADLAKRLERVLAAMVADPQRRLSSIAVLDEGERLRLDGWGNRTQGIQPATRDTSIPAAFAAQAARTPESVAVTCEERSLTYAELDGAANRLANLLAGRGVGPGQRVALVLPRSAEAIVAMLAVAKTGATYVPIDPAVPAARMRFVLDDSAPVAAVTTAALADRLDGCAAAVVDVDDPALAGDPGTPPPGPAPDDVAYIIYTSGTTGAPKGVAIPHRNVTRLLATLDAGMGLAGQVWTQCHSLAFDFSVWEIWGALLFGGRVVVVPDAVVRSPEDLHALLVAEQVTILSQTPSAFYALQSADAAQPGPRAELALEAVVFGGEALEPQRLRPWLDNHPAAPRLINMYGITETTVHASFREIVADDVDTAVSPIGVPLAHLGFFVLDGWLQPVPAGVVGELYVTGAGLADGYVGRAGLSATRFVACPYGAPGARMYRTGDLVWWGADGQLRYVGRADKQVKIRGYRIELGEIQAALAALDGVEQAVVIAREDRPGDKRLVGYVTGGADPAAARTALAERLPAYMVPAAVVALDALPLTVNGKLDTRALPAPEYQDGGQYRPPADAVEEILAGIYAQVLGLERVGVDESFFELGGDSILSMQVVARARAAGVVCRPRDIFVEQTVARLARVAAVVDGAADAIDEGVGPVVPTPIISWLHSIDGPVDQFNQTVVVQAPVGTTEADVVVVLQALLDRHAMLRLRVDEGADGAWSLQVPEPGSVDARHCLHAVQVLSEEALIEARSRLNPAAGVMLSALWVASTGRLVAIVHHLAVDGVSWRILLEDLNLAWAQHRGGQQLVLPAPGTSFARWASLLAEHAHRPDVVGQAETWQRIAAMPSALPAVQPAVDTYVSAGNLAAQLDVETSRMLLGEVPAAFHAGIHEILLIAFALACAEFLGTAGAPVVIDVEGHGRQEELADDVDLSRTVGWFTTKYPVAIDVGGLSWAQVVAGDAGLGAVVKDAKEQLRALPDGLTYGVLRYLNDDVDLDGSDPPIAFNYLGRAAAGTEASGDMWEICEDGLSLIDASARLPMPLAHTVELNAATVDAYTGPYLHAGWKWAPSALNEAQVSRLSRLWFDALAGICAHVRGGGGGLTPSDIAAGLTQQQIDELQRQYADS
>NZ_AP022614.1|WP_085270694.1|1926754_1926985_-|MbtH-family-protein
MSINPFDDDEGSFFVLVNNEEQHSLWPAFADVPAGWRVAYGETDRAACLDYIEQNWTDIRPRSLRERLAAGQGLDR
>NZ_AP022614.1|WP_139825910.1|1927448_1928579_+|methyltransferase-domain-containing-protein
MPRGAATTSSARPGTACRRVCRQAVACPAATANEGRNPGEDLISRPPTGVKRRPLRSQTSTLVWTRRLSGVRDSTTPCHKTSAKQIWLRRHKMDQLSEPSAQAESAGDSPVAMSAHLADDLLSTTATGWRSFYDSLSRRLEDVGVADSSFFLNYGYLPIDSNNDSAFVIRDGTFNANSVRLVFEVVGPVDLNDRTVVEIGCGRGGNSAQVAEKFSARVTGIDMSAEAIAFCRRTHRDSIDFQVGDALNIPLADEFCDAVINVESSHSYGNLPKFLNEVRRICRPGAWFLHTDFLSTDDWDYVRARLKALGFVTETDRDITANVLASRDQAKDNWAQVYGDGNARVANFLALPGSAIYEQLRAGLLEYRILRSQLRP
>NZ_AP022614.1|WP_163670809.1|1928589_1939611_-|SDR-family-NAD(P)-dependent-oxidoreductase
MTESFAIVGYAVRVPGAPDAEAFWDVLAQGRDAVSEVPPDRWDVDEFFDPDPDAPGKIVSRRAGFIDDVTGFDAPFFGLSNRETMLIDPQHRLLLETAWQAVEHSGTAPSALANTKTGVFMGLGTHDYLGLISEQLSYDEIEAYVAIGTSSAAGAGRISYGLGLQGPAVSVDTACSSSLVAVHQACQALRLKECDLALAGGVNVMLSAKTAMTFSHAHMLAPDGKCKTFDAAADGYVRGEGCGVVIVKRLEDAIRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVITEALEAAGVAPGDVGYLEAHGTGTSLGDPIEVQAAGAVLGAGREADRPLLIGSVKTNIGHLEAAAGIAGLIKVILSLEHEVLPKHLNFQKPSPHIPWDRLAVRVVDEAVPWERGGRPRIAGVSSFGFSGTNSHVIIEEAPTAVSAAQAEPVASDDRRFSLLPLSARSPAALTQLAEQYGSWLAEHPDASLADLCFTAGAARSHFEHRAALVVNSMESARECLGALAEGRPAPGLTKGECSDKPRTAWLFPGQGSQYAGMARELFETEPVFAETMTRCAAAVAEVLEKPLLDVIFDPDGDDTLRQTAYAQPALFAVEMGLARLWQSWGFEPDVVIGHSVGQYTAACVAGVFGLEDGALLLAERGRLFGSLPAGGRMVAVFAAAERVESLTDEFPNLSVAAYNGANTVLSGPADDLERAVALLEGDGVRCDWLETSHAFHSALLEPVLDEFESYANRFEFAPPQRTLVCNRTGAALGRSAKLDGAYWRRHARQPVEFAKSVRTLADLRCTMLLEVGPQPVLTAAAMRAWPDPATAPRAIASLRRNIADHRQITEALANAYVVGHVPDFGALPPGPARKLDLPTYPFQHRQYWFREQRSKPTAQSSADTQAARTEAVRLLEDGQFEELAALLGGNGDSQQTVDVLRQLAAQHNQQRQVQSITDSRYEIRWQKSAAGTAKTSAAAKGGEGSAWLIVSDDAATVAPLADALSARGHGHRVLGLPMSDADEKRLEATLRAAVDDDPALRILHVAALDSETAPSMQSLLRMQHHVLGGTRRLFRAAAAAELRAPIWLVTRGAQRVTNADKVSPVQSSLWGFGRAAALEYPRLWGGLADLSEGGAPDGGVWSRLIDYVLAAPRAEDQVALRDQAVYVPRLVRRAGLPVTSPLGLRADATYLVTGGLGGVGLEIAGYLAAQGARHLVLTSRRSPGEAAQQHIDAMREQHGCDVRVVAADVGNPHDVARLLSTVQAELPPLAGIVHAAGEIGNTPLQTLDDAEVDRVFAGKVWGAWNLSEATAGTRLDFFLSTSSISAAWGSFGQSAYSAANAFLDGLAWRQRERGVPAISVNFGPWSAAGMADEAARAELDKRGVRPLSPADALAGMAELMVASSAKGASHGIVARIDWAGFLPLYQLAGKRAFLSELEREVPEAAAAPVAAAGTTRLVEQLTVAPVQQRKKLVVDYLRDVVAEVTRIDPAEIRDEAGFFDVGMDSLMAVELRRRVEQAVGKELPSTLAMDYPRLVDVADFLLGDVLSFGAPGTTKEAASVDSRPSRLDPAVTMRSDEPIAIVAVACRFPGAPDPEAYWELLSGGVDAIREIPEDRFDVDEYYDPDPEAPGKIYTRYGGYLESIDGFDPEFFGISPREAVWMDPQQRLMLEISWEGLERAGYSPAALRGSRTGVFVGVAANEYSQLLNASSVETIEAHFITGNALNVIAGRVAFALGLEGPAMAVDTACSASLVAVHQACQALHSGDCDMALAGGVNVLVSPASIVATSRARMLSADGRCKTFDAAANGYARSEGCGILVLKRLSDAERDGDQICAVIRGSAVNQDGASSGLTVPNGGAQQRLIAATLARAGVEGRDVDYLEAHGTGTSLGDPIEVQAAAAVYGSGRDPNRPLLIGSAKTNIGHLESAAGIAGLIKVVLSLQHEMLPRNLHFENPSPNIPWDSLPVRVVDKPIAWRANGRPRRAGTSSFGFSGTNAHVLIEEAPAPVTGAVQPEAAQPDAAGEQVGVLPLSARSPEALTELAQEYGDWLEAHPAADLADVCFTAGVGRSHFEHRAALVVDSVQGARELLAGLAENKLGPGAVRGVCGDPPKTAWLFTGQGSQYPGMARELYDSEPVFAETVDRCAEAVDGLLPRPLLEVLFDTGETGAETLRHTSFAQPALFAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAGVFSLEDGARLMAERGRLFGELPEGGRMVAVFADPQRVERAAEDFPHISVAAYNGPNTVLSGPGGDLEQIVEKLTADEIRCTWLDTSHAFHSELLEPALDEFEAYAKGFEFAVPALPLVCNRTGAVLTAENPLDAHYWRRHSRQPVQFAESVQTVAKLGCSVLMEIGPQPVLTGAALQAWPDSSAAPQAVVSLRKGTDARRQMAEALAAAYVAGHRPDFAAVHHRMHRRLELPTYPFQRRRFWPKSADIRGVDGQGVITSGILGSAKDLASGDAVYTSRWSIKTQPWLAHHVIYGTVVVPGATYAAMALAAVGTPAQVREVFFYEPIILGDKTSREVQLSVHPVEDGGGWTFQVHSRPYGDRGAEWALNADGRIADSIDDAPAPEPTESIDSACERLGRMRPQQLFDTFADMELTWGPTWSTSLKSLWSGDGEAVGDISIGDELAEQLGGEPIHPVLLDLCTGVAFPAFPAVLTENEHGDAMTDLFLPLRYGRVVLRETLPRRFYCRARWNSGGPDSETQVFDLDFVDREGRQLGEVREFTVKRAPREALLRGIGGDATRNLYTLGWEEVPPPSGNAADNGEGTWLIAGFDELAAALPNAVAVGRTTDPEAWTRLLAQAQERSAPVCGIVWRGTARPDADESNADFAARLETEIDELVTVVRTLLAQHDMKLTGGLWILTERGVATEPGEPVDPAQSALWGFGRTVITEQPMLRCRLVDYDGFDDAARSLAGLLGTPGEEPELALRQGKYLVPRLLPWGRSGHLAVPRSADYVLAPTERGAIDNLRLFETQVPAPAAGEVQIRVEAAGLNFRDVLNVLGLYPGDPGQIGGGDLAGVVTELGAGVTGLEVGQRVFGFMPGSFATRVNAPAQFLTPVPNGISSVAAATIPAGALTTRLAFDWANVGPGDRVLIHAASGGVGLAAVQMARQRGATVFATASTYKRAALRKMGVEHVYDSRSTDFADQILADTGGAGVDVVLNSLTNEGFIEATVRATAQGGRFAEIAKRDIWTREQMAAARPDISYEIIALDGCIEAEPERVGRLLAEVAESMANGELEPIAAEVYPVTEAKSAFRRMQQARHIGKIVLQMPRPLQPRGDRSYLITGGLGALGLFTAAHLAQLGAGDIVLTSRRAPDAEAQRSIDDITERYRCRIHTFTADVGDESEVATLLERIRAELPPLAGVAHLAGVLDDALLTQQSVEHFRTTLAPKAFGARYLDRLTRDDDLEFFVMYSSAASVIGSPGQANYASANALLDGLVADRRAQGLPATGINWGPWAKGGMATSHAARANLSAQGLIPLEPTAALSALDEVVANGTAQATVLKANWQRAAKGLGSSRPAMLDHVLPSDVTAARGDSELLRQLHDVPEAQRGSFLTEYLRHEVQNFLRLAQPPAATSRFLELGTDSLMAVEFSNRLLPQFGGAFTISATAVFDYPTIGSLAEYLAGQVPESALEVNGAESVAASEPTQ
>NZ_AP022614.1|WP_085269528.1|1940016_1941285_-|glycosyltransferase
MKFVLASWGSRGDVEPNLAVGRELVRRGHDVCMAVPPDLVGFTEAAGVPAVGFGPEARSILDAHREFWTCFFSHPWRIRKLITSRLDIAGPLLRGWQEMSTTLTSLADGADLIFTGINFEDAAANVAEHFDIPLATLHYFPLRPNGQTLRFLPAPLARQAVAAFWWVSWRGMKKAENAQRLELGLPPASGSAPRRITERGSLEIQAYDEACFPGLAREWAARAGQRPFVGTLTLDLQTDADEEVASWIAAGTPPVFFGFGSIPVESPADTIAMIAAACSRLGERALVGAAGTDFGDVPHFDHVKVVGTMNYATVFPACRAVVHHGGSSTTPIAMRAGVPQLILFWDLVHAVYGAAVKRLKVGTARRFSSATEESLVADLSTILAPDYAERAGALATHITEPAKSAAAATDLLENFARRRPAG
>NZ_AP022614.1|WP_085269531.1|1941741_1942464_+|rhamnosyl-O-methyltransferase
MFESASTPWDFFKKTIAIPSLARHFYQPTGSECEEYHKWFYNTGVFNHMTWMGVMCQKSASDMWNYQEILFELKPSLVIEFGTNQGGSALFFASVMRQIGAPFKVLSVDVYHGPLEPRARRDSDILFVESRSTVPAVAQHIQRLKEEYPGRIFAILDSDHSMNHVLAEMKLLRPLLSAGDYLIVEDSNMNGHPVLPGWGPGPYEAIEAYEREFPNDYKHDVARENKFGWTQAPNGYLIRN
>NZ_AP022614.1|WP_085269530.1|1942497_1943232_-|class-I-SAM-dependent-methyltransferase
MLADAWPGVNRIRAVQRALAGRPDPVYLEIGVSRGQAFQRIAADVKIAVDPAFKLSERTRQLSDAKGRETHYFETTSDAFFENETAFLERHPIDVALIDGLHTYEQVVRDVEYTLRYLRDDGVIFLHDCNPPFALAGRRAESWDEFVAQQSGPLVIGIWNGDVWKAIVQLRSTRPDLLVGVLKCDQGVGFVRKGSPESTLPYSVEQVEALTYADLKADRERLLNLKPTRYLNEFLAAGAGSPPR

Crispr_ID: NZ_AP022614_4

• CRISPR_ID: NZ_AP022614_4
• CRISPR_location: 2419527-2419610
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_AP022614_4

Consensus_repeat	Method
CTAGCCCGGCGACGATGCGCGCCGC	CRISPRCasFinder

spacers of NZ_AP022614_4

>4.1|2419552|34|NZ_AP022614|CRISPRCasFinder
GAAGCGGCGCGAGGAGGAGTCGGGCAATCCAGCT

CRISPR arrays and Neighbor proteins around NZ_AP022614_4

CRISPR arrays

The CRISPR arrays of NZ_AP022614_4

>merge|NZ_AP022614|4|2419527-2419610|CRISPRCasFinder
CTAGCCCGGCGACGATGCGCGCCGCGAAGCGGCGCGAGGAGGAGTCGGGCAATCCAGCTCTAGCCCGGCGACGATGCGCGCCGC

>NZ_AP022614|4|4|2419527-2419610|CRISPRCasFinder
CTAGCCCGGCGACGATGCGCGCCGC	GAAGCGGCGCGAGGAGGAGTCGGGCAATCCAGCT
CTAGCCCGGCGACGATGCGCGCCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP022614.1|WP_085267385.1|2414024_2414339_+|antibiotic-biosynthesis-monooxygenase	unknown	unknown	gnl|CDD|224278
NZ_AP022614.1|WP_161494163.1|2424036_2424483_+|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|238075
NZ_AP022614.1|WP_085267393.1|2422997_2423738_+|dienelactone-hydrolase-family-protein	unknown	unknown	gnl|CDD|366780
NZ_AP022614.1|WP_085267390.1|2419636_2420950_-|winged-helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|225755
NZ_AP022614.1|WP_085267428.1|2422153_2422954_-|thymidylate-synthase	unknown	unknown	gnl|CDD|234984
NZ_AP022614.1|WP_085267388.1|2416052_2417729_-|ribonuclease-J	unknown	unknown	gnl|CDD|223668
NZ_AP022614.1|WP_085267382.1|2410037_2410637_-|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase	unknown	unknown	gnl|CDD|273139
NZ_AP022614.1|WP_085267427.1|2418763_2419516_-|FAD-dependent-thymidylate-synthase	unknown	unknown	gnl|CDD|234847
NZ_AP022614.1|WP_085267397.1|2425697_2428940_-|carbamoyl-phosphate-synthetase	unknown	unknown	gnl|CDD|237263
NZ_AP022614.1|WP_085267381.1|2409618_2409945_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|238045
NZ_AP022614.1|WP_085267395.1|2424510_2425290_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|235975
NZ_AP022614.1|WP_139825593.1|2414335_2415157_+|mycofactocin-coupled-SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|274889
NZ_AP022614.1|WP_085267396.1|2425380_2425707_+|PE-PGRS-family-protein	unknown	unknown	unknown
NZ_AP022614.1|WP_085267383.1|2410675_2411209_+|amino-acid-N-acetyltransferase	unknown	unknown	gnl|CDD|236132
NZ_AP022614.1|WP_085267429.1|2428936_2430460_-|AMP-binding-protein	unknown	unknown	gnl|CDD|341286
NZ_AP022614.1|WP_085267392.1|2421662_2422157_-|dihydrofolate-reductase	unknown	unknown	gnl|CDD|365932
NZ_AP022614.1|WP_085267384.1|2411279_2413865_-|DNA-translocase-FtsK	unknown	unknown	gnl|CDD|224588
NZ_AP022614.1|WP_085267391.1|2420888_2421572_-|DivIVA-domain-containing-protein	unknown	unknown	gnl|CDD|274008
NZ_AP022614.1|WP_085267387.1|2415159_2416032_+|SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|272862
NZ_AP022614.1|WP_085267389.1|2417748_2418651_-|4-hydroxy-tetrahydrodipicolinate-synthase	unknown	unknown	gnl|CDD|235107

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP022614.1|WP_085267385.1|2414024_2414339_+|antibiotic-biosynthesis-monooxygenase	gnl|CDD|224278	COG1359, COG1359, Uncharacterized conserved protein [Function unknown].	7.01833e-25
NZ_AP022614.1|WP_161494163.1|2424036_2424483_+|PAS-domain-S-box-protein	gnl|CDD|238075	cd00130, PAS, PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in signal transduction.	3.45138e-08
NZ_AP022614.1|WP_085267393.1|2422997_2423738_+|dienelactone-hydrolase-family-protein	gnl|CDD|366780	pfam01738, DLH, Dienelactone hydrolase family.	9.35775e-62
NZ_AP022614.1|WP_085267390.1|2419636_2420950_-|winged-helix-turn-helix-domain-containing-protein	gnl|CDD|225755	COG3214, COG3214, Uncharacterized protein conserved in bacteria [Function unknown].	7.93366e-104
NZ_AP022614.1|WP_085267428.1|2422153_2422954_-|thymidylate-synthase	gnl|CDD|234984	PRK01827, thyA, thymidylate synthase; Reviewed.	0
NZ_AP022614.1|WP_085267388.1|2416052_2417729_-|ribonuclease-J	gnl|CDD|223668	COG0595, COG0595, mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair].	0
NZ_AP022614.1|WP_085267382.1|2410037_2410637_-|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase	gnl|CDD|273139	TIGR00560, pgsA, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase. Alternate names: phosphatidylglycerophosphate synthase; glycerophosphate phosphatidyltransferase; PGP synthase. A number of related enzymes are quite similar in both sequence and catalytic activity, including Saccharamyces cerevisiae YDL142c, now known to be a cardiolipin synthase. There may be problems with incorrect transitive annotation of near homologs as authentic CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase. [Fatty acid and phospholipid metabolism, Biosynthesis].	3.14008e-34
NZ_AP022614.1|WP_085267427.1|2418763_2419516_-|FAD-dependent-thymidylate-synthase	gnl|CDD|234847	PRK00847, thyX, FAD-dependent thymidylate synthase; Reviewed.	1.59023e-97
NZ_AP022614.1|WP_085267397.1|2425697_2428940_-|carbamoyl-phosphate-synthetase	gnl|CDD|237263	PRK12999, PRK12999, pyruvate carboxylase; Reviewed.	4.81947e-161
NZ_AP022614.1|WP_085267381.1|2409618_2409945_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	3.11664e-10
NZ_AP022614.1|WP_085267395.1|2424510_2425290_-|SDR-family-oxidoreductase	gnl|CDD|235975	PRK07231, FabG-like, SDR family oxidoreductase.	6.37651e-123
NZ_AP022614.1|WP_139825593.1|2414335_2415157_+|mycofactocin-coupled-SDR-family-oxidoreductase	gnl|CDD|274889	TIGR03971, short-chain_dehydrogenase/reductase_SDR, SDR family mycofactocin-dependent oxidoreductase. Members of this protein subfamily are putative oxidoreductases belonging to the larger SDR family. All members occur in genomes that encode a cassette for the biosynthesis of mycofactocin, a proposed electron carrier of a novel redox pool. Characterized members of this family are described as NDMA-dependent, meaning that a blue aniline dye serving as an artificial electron acceptor is required for members of this family to cycle in vitro, since the bound NAD residue is not exchangeable. See EC 1.1.99.36. [Unknown function, Enzymes of unknown specificity].	4.88465e-140
NZ_AP022614.1|WP_085267383.1|2410675_2411209_+|amino-acid-N-acetyltransferase	gnl|CDD|236132	PRK07922, PRK07922, amino-acid N-acetyltransferase.	3.71602e-117
NZ_AP022614.1|WP_085267429.1|2428936_2430460_-|AMP-binding-protein	gnl|CDD|341286	cd17631, FACL_FadD13-like, fatty acyl-CoA synthetase, including FadD13. This family contains fatty acyl-CoA synthetases, including Mycobacterium tuberculosis acid-induced operon MymA encoding the fatty acyl-CoA synthetase FadD13 which is essential for virulence and intracellular growth of the pathogen. The fatty acyl-CoA synthetase activates lipids before entering into the metabolic pathways and is also involved in transmembrane lipid transport. However, unlike soluble fatty acyl-CoA synthetases, but like the mammalian integral-membrane very-long-chain acyl-CoA synthetases, FadD13 accepts lipid substrates up to the maximum length of C26, and this is facilitated by an extensive hydrophobic tunnel from the active site to a positively charged patch. Also included is feruloyl-CoA synthetase (Fcs) in Rhodococcus strains where it is involved in biotechnological vanillin production from eugenol and ferulic acid via a non-beta-oxidative pathway.	5.48562e-131
NZ_AP022614.1|WP_085267392.1|2421662_2422157_-|dihydrofolate-reductase	gnl|CDD|365932	pfam00186, DHFR_1, Dihydrofolate reductase.	5.45896e-56
NZ_AP022614.1|WP_085267384.1|2411279_2413865_-|DNA-translocase-FtsK	gnl|CDD|224588	COG1674, FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning].	1.33134e-180
NZ_AP022614.1|WP_085267391.1|2420888_2421572_-|DivIVA-domain-containing-protein	gnl|CDD|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	4.63341e-07
NZ_AP022614.1|WP_085267387.1|2415159_2416032_+|SAM-dependent-methyltransferase	gnl|CDD|272862	TIGR00027, Hypothetical_protein_Rv0893c/MT0917/Mb0917c., methyltransferase, TIGR00027 family. This model represents a set of probable methyltransferases, about 300 amino acids long, with essentially full length homology. Members share an N-terminal region described by Pfam model pfam02409. Included are a paralogous family of 12 proteins in Mycobacterium tuberculosis, plus close homologs in related species, a family of 8 in the archaeon Methanosarcina acetivorans, and small numbers of members in other species, including plants. [Unknown function, Enzymes of unknown specificity].	3.54801e-70
NZ_AP022614.1|WP_085267389.1|2417748_2418651_-|4-hydroxy-tetrahydrodipicolinate-synthase	gnl|CDD|235107	PRK03170, PRK03170, dihydrodipicolinate synthase; Provisional.	2.5512e-142

Protein sequences

>NZ_AP022614.1|WP_085267427.1|2418763_2419516_-|FAD-dependent-thymidylate-synthase
MAQIAPLRVQLIARTEFVAPPDVPWSTDADGGPALVEFAGRACYQSWSKPNPRTATNAGYIKHIIDVGHFSVLEHASVSFYITGISRSCTHELIRHRHFSYSQLSQRYVPEDTSRVVMPPGMEDDPELRQMLADAADASRATYVELLAKLEAKFADQPSAVLRRKQARQAARAVLPNATETRIVVTGNYRAWRHFVAMRASEHADVEIRRLAIECLRQLAAVAPAVFADFEISALADGTEVATSPLATEA
>NZ_AP022614.1|WP_085267389.1|2417748_2418651_-|4-hydroxy-tetrahydrodipicolinate-synthase
MSNVGFEASSRLGTLLTAMVTPFGADGSLDTAAAARLANHLVGAGCDGLVVSGTTGESPTTTDDEKRELLRVVLEAVGDRARVIAGAGTYDTAHSVRLAKACEAEGAHGLLVVTPYYSKPPQSGLIAHFTAVADATALPVLLYDIPPRSVVPIQTETIRTLAEHPNIVGIKDAKGDLHSGGQVMAETGLAYYSGDDALNLPWLAMGATGFISVISHLAAAQLRELLSAFGSGDMATARKINGNLAPLCNAMARLGGVTLSKAGLLLQGIDVGAPRLPQMPATAGQLDELAADMRAASVLR
>NZ_AP022614.1|WP_085267388.1|2416052_2417729_-|ribonuclease-J
MDVDFAPPGPLVAGGLRVTALGGISEIGRNMTVLEHLGKLLIIDCGVMFPTHDEPGVDLILPDLRHIEDRLDDIEALVLTHAHEDHIGGIPFLLRLRPDIPVVGSRFTLALVAAKCREHRLKPAFVEVAEGQTSRHGVFECRYFAVNHSIPDALAIAVTTGAGTILHTGDIKLDQLPLDGRPTDLPGMSRLGDAGVDLFLCDSTNSEIPGVGPSESEVGPTLHRLIRGAEGRVIVACFASNVDRVQQIIDAAVALGRRVSFVGRSMVRNMGIARDLGFLRVDDSDLLDIAAAETMPPERVVLITTGTQGEPMSALSRMSRGEHRSITLTAGDLIVLSSSLIPGNEEAVYGVIDSLAKIGARVVTNAQARVHVSGHAYAGELLFLYNGVRPRNVMPVHGTWRMLRANAQLAARAGVPRESILLAENGVSVDLVSGRASIAGAVPVGKMFVDGLITGDVGDITLGERLILSSGFVAVTVVVTRGTGRPVGPPQLHSRGFSEDPKALEPAVRKVGAELESLVAAGVTDPGRIAQGVRRTVGKWVGETYRRQPMIVPTVIEV
>NZ_AP022614.1|WP_085267387.1|2415159_2416032_+|SAM-dependent-methyltransferase
MAPNPAAQTAFGPMVLAAVEQNEPPERRLVDDDLAQLFLPPALRRLVAATRYAPVRRLVIRASEFTGPGLWANLACRKRFIGDKLADALGDVDAVVILGAGLDTRPYRLTRQVRIPVFEVDLPVNIARKAETVRRVLGGPPLSVRLVALDLERDDLLTSLAEHGYLPDYRVFFICEGVTQYLSEATVRRTLEGLRAAAPGSRLVFTYVRRDFIDGTNRYGTRTLYRNVRQRRPLWQFGLQPDEVAGFVAEYGWRLVEQAGPDELVERYVESTGRKLKASQLEWSAYAEKA
>NZ_AP022614.1|WP_139825593.1|2414335_2415157_+|mycofactocin-coupled-SDR-family-oxidoreductase
MMARPLDGKVAFITGAARGQGRAHAVRLATDGAAIIAVDLCDQIASVPYPLASPEDLAATVKLVEDTGARIVATRGDVRDRASVSSALQAGLDEFGRLDIVVANAGIAPMQSGDDGWRDVIDVNLTGVYNTIKAAIPTMVSQGDGGSIVLISSSAGLAGVGSPDAGSVGYAAAKHGVVGLMRIYANLLARENIRVNSIHPSGVETPMINNEFTREWLARMAAAVDNPGALGNAMPVETLQAEDIANAVAWLVSDQARYVTGVTLPVDAGFLNK
>NZ_AP022614.1|WP_085267385.1|2414024_2414339_+|antibiotic-biosynthesis-monooxygenase
MPVVVVATMTVKPESVDTVRDILTRAVEEVHEEPGCQLYSLHQSGETFVFVEQWADPEALKAHSTAPAVTKMFTAAGEHLDGAPDIKMLQPVPAGEPDKGQLRP
>NZ_AP022614.1|WP_085267384.1|2411279_2413865_-|DNA-translocase-FtsK
MANKTAARSGTRTSRSKASSRGGPRGGSRSGARGARPAPARGRVSRPARRRNSPLLVAAGLACGRALRGTWMMAARGTGGAARSIGRARDIDPGHRRDGIALLLLGVAVVVAASSWFDAARPVGAWVDTLLRTFVGSGVLVLPVVAAAVAVALMRTEPNPDARPRLILGASLIAFSLLGLRHLWSGSPEDPEARRRAGGFIGFAIGGPLSDGLTPWIAAPLLFIGALFGLLLLTGTTIREVPDVVRAMFGNRLFGGDDDEYDDFSDFSDFSDFSDFADEPDEPVDDAGAAREDFSDGYVDEASPATQSEPQAWPSADSDQAPLEDDVPTVPEPAVKEAAARGRRRGKADQDTIELDRVVEGPYTLPPLSLLVAGDPPKKRSAANNVMADAISEVLNQFKVDAAVTGCTRGPTVTRYEVELGPGVKVEKITALQRNIAYAVATESVRMLAPIPGKSAVGIEVPNTDREMVRLADVLTAPSTRRDHHPLIIGLGKDIEGDFISANLAKMPHLLVAGSTGSGKSSFVNSMLVSLLARATPEEVRMILIDPKMVELTPYEGIPHLITPIITQPKKAAAALAWLVEEMEQRYQDMQASRVRHIDDFNAKVRSGAITAPLGSQREYRPYPYVVAIVDELADLMMTAPRDVEDAIVRITQKARAAGIHLVLATQRPSVDVVTGLIKTNVPSRLAFATSSLTDSRVILDQPGAEKLIGMGDGLFLPMGASKPVRLQGAFITDEEIQAVVSACKDQAEPEYTEGVTTAKPTGERTDVDPDIGDDMDVFLQAVELVVSSQFGSTSMLQRKLRVGFAKAGRLMDLMETRGIVGPSEGSKAREVLVKPDELAGTLALIRGGANADGSGDPDTE
>NZ_AP022614.1|WP_085267383.1|2410675_2411209_+|amino-acid-N-acetyltransferase
MPILLAVTESSPDLPAVVRRARTSDVPAIKQLVDTYAGKILLEKNLVTLYEAVQEFWVAEYQGQVVGCGALHVMWADLGEIRTVAVDPSVTGHGIGHAIVDRLLEVARELQLKRLFVLTFETEFFARHGFTEIEGTPVTAEVYEEMCRSYDIGVAEFLDLSYVKPNILGNSRMLLRL
>NZ_AP022614.1|WP_085267382.1|2410037_2410637_-|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase
MSGQPRTGPLTGPPGRVRIANLANALTLSRLVLVPIFLLALFAGDGHQTAFRVVAFVIFAVASITDRLDGLLARHYGMATEFGAFVDPIADKTLIGSALIGLSMLGNLPWWVTVLILTREIGITLLRLIVIRRGVIPASWGGKLKTVVQSLAIALFILPLSGPLLVAASVLMGAAIVLTVVTGVDYVASTVRAVRQPTV
>NZ_AP022614.1|WP_085267381.1|2409618_2409945_-|helix-turn-helix-transcriptional-regulator
MPPLVREVIGDVLRDARTSQGRTLREVSDSARVSLGYLSEVERGRKEPSSELLNAICDALDVPLSSVLTDAGERMAGQERRLAGETAGSSIDATTKVVIPPVASLAVA
>NZ_AP022614.1|WP_085267390.1|2419636_2420950_-|winged-helix-turn-helix-domain-containing-protein
MRPTTNKRIHRTRTPWRERGRSHSREQTAGTLGAVSIRNRRLTVAQARRIAVAAQGFTDPRPGRDITAAHLKRLISRIQVLQLDSVSVAVRAHYAPVFSRLGPYDRDVLDRAAWGPRRARLLVEYWAHEAALMSVDDWPLLRWRMREYRHGRWGTHIVQANPQLADDVVDAVAALGPSTAGQIEAHLAQTPRRRKGAWWNRSDTKWVAEALFASGVLTTATRVGFARHYDLVERVLPPRVLARQVDDGEAVRELVLRAATALGVGAEADIRDYFRLSARQVKPAIAELVAGGEIEPVEVDGWQAPAYLRAGRTVPRLDRGTALLCPFDPLIFFRPRVERLFGFHYRVEIYVPAARRRYGYYVWPLLLDGQLVARVDLKADRAAGTLRVVGAFSEAGQPRARVAAALAGELESMASWLGLSGISVSSRGDLAGELRRR
>NZ_AP022614.1|WP_085267391.1|2420888_2421572_-|DivIVA-domain-containing-protein
MITEPAKKFSRKLAGYDPAAVDAHIEVLTTKQKLLVDDVESLRARLHASGEEAAALRKEVAVLTDTSPSPHAVQQRMAKMLRRAVDEIAEMQAEARSEAEALIAAAEAEVRATERQRDELLADMAARREAMETEYREAKDQLEAELAGLRADAHQAREQLLAEAKQRAEHDREEARQAVEEASRQRIRILEQLMGVYRDLESVPHALDAAYHEQKNPSDANAVARTG
>NZ_AP022614.1|WP_085267392.1|2421662_2422157_-|dihydrofolate-reductase
MTPKMQVGLVWAQSTSGVIGRGGDIPWRVPEDLARFKEVTMGHTVVMGRLTWESLPVRVRPLPGRKNIVMSRQAGFTADGAEVVGRIEDALVDPLTWVIGGAQIYLLALPHATRCEVTEVDIDLRRDDDDAVAPMLDDAWVGEAGDWCVSRSGLRYRFHSYSRP
>NZ_AP022614.1|WP_085267428.1|2422153_2422954_-|thymidylate-synthase
MPIPTPYEDLLRLVLERGAVKSDRTGTGTRSLFGQQLRYDLSAGFPLVTTKKVHLKSIVYELLWFLRGDSNVGWLREHGVTIWDEWASSTGDLGPIYGVQWRSWPTPSGEHVDQISAAVDLLRNDPDSRRIIVSAWNVGEIPRMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASYALLTHMMAAQAGLEVGEFVWTGGDCHIYDNHVEQVRLQLGREPRPYPELVLAQRDSIFDYTYDDVVVKNYDPHPAIKAPVAV
>NZ_AP022614.1|WP_085267393.1|2422997_2423738_+|dienelactone-hydrolase-family-protein
MPKITDSVTTADGSCPVSLFTPDGPGPWPGVVMFPDAGGVRDTFDQMAAKLAGYGYAVLLPDVYYRSGDWAPFDMATVFSDEQERKRLFSMIGGITADKITTDAGAFFDFLAARPEVSGERFGACGYCMGGRTSLVVAGRLPERVAAAASFHGGGLVTDAADSPHLLADRMRATIYVGGARNDASFTAEHAEQLDKALTAAGVAHTIEWYAAGHGFAVPDNPPYDPAAAERHWQAMTEVFGSALTG
>NZ_AP022614.1|WP_161494163.1|2424036_2424483_+|PAS-domain-S-box-protein
MTESTSGKRRRVERRRPTPPDQLPIDALQQMPALVVLERLPAPALAVDRAGMILFANRSFCDMLGYLPAELASMKFDELLRRRTVGKRRVALNGTDIERLVELKHSDGHALRVSMSRSAMHRRDDLVALVTFHDRTEEFWVDPKKKGD
>NZ_AP022614.1|WP_085267395.1|2424510_2425290_-|SDR-family-oxidoreductase
MTSQDLTGRTAIITGASRGIGLAIAQQLAAAGADVVLTARKQEAAEEAAAQVGPRALGVGAHAVDEDAARRCVDVTLERFGRIDILVNNAGTNPAFGPLIDQDHARFAKIFDVNLWAPLMWTSLAVKAGMGEHRGSVVNTASIGGLHQSPGMGMYNATKAALIHVTKQLALELSPRVRVNAICPGVVRTKLAEALWKDNEDPLSSSIALGRIGEPVDVAAAVAFLVSDAASWITGETMVIDGGLLLGAAQGFRAHPTGG
>NZ_AP022614.1|WP_085267396.1|2425380_2425707_+|PE-PGRS-family-protein
MKSVVAAGAAAAAIVVAPTAVADFLAAAPASTAAPAHVVVKDDPGGGGCDANGNCGSGGQFSGPGGGPGGQGCVPGVGCGSGGQNAGPGGIPGGAGCLPGVGCGSGHA
>NZ_AP022614.1|WP_085267397.1|2425697_2428940_-|carbamoyl-phosphate-synthetase
MSATLLIANRGEIALRIIRTATELGMRTVAVYAEDDAETPHVHAADEAIALSGAGPQTYLDQAAVLAAADRCGAELIHPGYGFLSENPGFARACAAAGHTFVGPDPDVLELLGNKSSARRAAADAGVPVLPATEGPSTLEDVRAFFADHDGGIMIKALAGGGGRGMRAVRGAGDIDDAYRQCAAEAQLGFGDSALFAEALFDDARHLEVQVVAAPVGHQPRALALGDRDCSVQRRHQKLIEIAPAQEISDKLRRDLHHAAARLCARVGVRGVATVEFLVAGESFAFLEVNPRIQVEHTVTEETTGVDLVAAQLAIAAGASYYELGLPAGIASDGIEVIGEPTAHRGTAVQARVNMETFAADGSVVPAAGTLTAFSPPAGPGVRVDTYGRPGLVTSPRYDSLLAKVTAHVRGSSLPAAARKASAALAEFDIEGVGTNIELLREILSQDDFQSATVTTGFLDRKLPGLAAAALSRHRETRVSAVELYPGEEVLRAHLAGTVVEVAPDGTEFDSGAQLVVLEAMKMQHVLRAPAGLRTVRSLVAPGQVVGTGDPLLVFVRAGADADDEKSSAATDLDQPRADLDEVRRRHLLTLDEGREAAVAKRHSRGRRTARENIADLVDAGSFVEYGGLAVAAQRSRRSEEDLIANTPADGLIAGLATIGADRFGHAAAEALVVSYDYTVLAGTQGMRNHAKTDRVFEVAARKRVPVVLFAEGGGGRPGDTDVGGAAGLDVPTFRMLAGLRGRVPLVAIVSGRCFAGNAALAGVCDVIIATPDANIGMGGPAMIEGGGLGVYPPEAIGPIDVQRRNGVVDLVARDEAHAVALARQYLSYFLRRLPGWEPPDPRLARHVVPQNRLRAYDVHRAVEAVVDVGSALVLRPDYGVGIVTALVRVEGRAYGLMANSSHHLGGAIDAEAADKASDFLTLCETFRLPVISLCDTPGFMVGPESEKEAAVRRFGRMFVTGARLTVPLGMIILRKGYGLGAMAMAGGSFRAPQFTIAYPTGEIGGMGLEGAVRLGFSKELAALDDPAERAALFDRLVAAAYEHGKALRAATTFELDDVIDPADSRAWITRLGSSGKDQA
>NZ_AP022614.1|WP_085267429.1|2428936_2430460_-|AMP-binding-protein
MTEIARGANPFPTTGVSRDARGVPHYDDLPDTLLDMLADQVDRRPDSEAVVEPGAGRLTYRQLWERAARVAGGLRAAGLRRGDRVAVRRPAGIDWVLAFWGAVMAGGVAVAVNTRSAQPEVDFVLSDSGARGDLSADAPLPDGQPYVSTELGPRDTAALFYTSGTTGHPKGVPTTHEAFLTNAENNLRCLDQPRDLGEEMRTLISVPLFHVTGCNTQLLVAMRLGGAAVIMPALDLEELIATLSAERISSMVTVPAIYSLLLRHKGFASADVSGVRWVGYGGAPIAPSLVRSVKDAFAAATVFNGYGMTETASLMTVLPDADALAHADSVGYAVPSVDLAVIGSGADSRTGELVVRGANVTAGYWNRPEATEATIVDGWLHTGDVVRVDDAGRVHLVDRLKDIINRGGENVSSVEVEAVLLAAPGVADACVLAVPDDVMGEKVGAVLFGGPDRVDVPAVLEHCRGRLADFKIPQYVTVVHGPLPRNAGGKLLKARLRRQVRWGDPLR

Crispr_ID: NZ_AP022614_5

• CRISPR_ID: NZ_AP022614_5
• CRISPR_location: 3519924-3520001
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_AP022614_5

Consensus_repeat	Method
GTCATCGGCGCCACTCCTTCTCATC	CRISPRCasFinder

spacers of NZ_AP022614_5

>5.1|3519949|28|NZ_AP022614|CRISPRCasFinder
GCTGCGCTCTGCATCGTCGTAGGCGCGC

CRISPR arrays and Neighbor proteins around NZ_AP022614_5

CRISPR arrays

The CRISPR arrays of NZ_AP022614_5

>merge|NZ_AP022614|5|3519924-3520001|CRISPRCasFinder
GTCATCGGCGCCACTCCTTCTCATCGCTGCGCTCTGCATCGTCGTAGGCGCGCGTCATCGGCGCCACTCCTTCTCATC

>NZ_AP022614|5|5|3519924-3520001|CRISPRCasFinder
GTCATCGGCGCCACTCCTTCTCATC	GCTGCGCTCTGCATCGTCGTAGGCGCGC
GTCATCGGCGCCACTCCTTCTCATC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP022614.1|WP_085271800.1|3514333_3515167_-|thioesterase-family-protein	unknown	unknown	gnl|CDD|379298
NZ_AP022614.1|WP_085271803.1|3511560_3512688_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|187551
NZ_AP022614.1|WP_085271793.1|3522179_3522695_-|YbjN-domain-containing-protein	unknown	unknown	gnl|CDD|371210
NZ_AP022614.1|WP_085272056.1|3510478_3511555_-|acyltransferase-family-protein	unknown	unknown	gnl|CDD|153249
NZ_AP022614.1|WP_139826018.1|3520036_3521257_-|sensor-histidine-kinase	unknown	unknown	gnl|CDD|274368
NZ_AP022614.1|WP_085271788.1|3528805_3529315_+|DUF2505-domain-containing-protein	unknown	unknown	gnl|CDD|378476
NZ_AP022614.1|WP_085271796.1|3518377_3519163_+|hypothetical-protein	unknown	unknown	unknown
NZ_AP022614.1|WP_085271797.1|3517077_3518094_-|Ppx/GppA-family-phosphatase	unknown	unknown	gnl|CDD|367122
NZ_AP022614.1|WP_085271794.1|3521408_3522158_-|phosphoglyceromutase	unknown	unknown	gnl|CDD|184519
NZ_AP022614.1|WP_003402602.1|3512747_3512849_-|AURKAIP1/COX24-domain-containing-protein	unknown	unknown	unknown
NZ_AP022614.1|WP_085271802.1|3513035_3513293_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|200128
NZ_AP022614.1|WP_085271798.1|3516052_3517081_-|hypothetical-protein	unknown	unknown	gnl|CDD|237057
NZ_AP022614.1|WP_085271801.1|3513433_3514321_-|pyrroline-5-carboxylate-reductase	unknown	unknown	gnl|CDD|237008
NZ_AP022614.1|WP_085271799.1|3515182_3516025_-|sugar-phosphate-isomerase/epimerase	unknown	unknown	gnl|CDD|224007
NZ_AP022614.1|WP_139826017.1|3526245_3527592_-|L,D-transpeptidase-family-protein	unknown	unknown	gnl|CDD|380079
NZ_AP022614.1|WP_085271789.1|3527663_3528779_-|UDP-N-acetylmuramate-dehydrogenase	unknown	unknown	gnl|CDD|237552
NZ_AP022614.1|WP_085271791.1|3524026_3525340_-|ROK-family-protein	unknown	unknown	gnl|CDD|224851
NZ_AP022614.1|WP_085271790.1|3525512_3526262_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|226674
NZ_AP022614.1|WP_085271787.1|3529337_3530168_+|carbon-nitrogen-hydrolase-family-protein	unknown	unknown	gnl|CDD|143605
NZ_AP022614.1|WP_085271792.1|3522691_3523966_-|D-inositol-3-phosphate-glycosyltransferase	unknown	unknown	gnl|CDD|132490

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP022614.1|WP_085271800.1|3514333_3515167_-|thioesterase-family-protein	gnl|CDD|379298	pfam13622, 4HBT_3, Thioesterase-like superfamily. This family contains a wide variety of enzymes, principally thioesterases. These enzymes are part of the Hotdog fold superfamily.	3.6073e-43
NZ_AP022614.1|WP_085271803.1|3511560_3512688_-|SDR-family-oxidoreductase	gnl|CDD|187551	cd05240, UDP_G4E_3_SDR_e, UDP-glucose 4 epimerase (G4E), subgroup 3, extended (e) SDRs. Members of this bacterial subgroup are identified as possible sugar epimerases, such as UDP-glucose 4 epimerase. However, while the NAD(P)-binding motif is fairly well conserved, not all members retain the canonical active site tetrad of the extended SDRs. UDP-glucose 4 epimerase (aka UDP-galactose-4-epimerase), is a homodimeric extended SDR. It catalyzes the NAD-dependent conversion of UDP-galactose to UDP-glucose, the final step in Leloir galactose synthesis. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	2.32979e-98
NZ_AP022614.1|WP_085271789.1|3527663_3528779_-|UDP-N-acetylmuramate-dehydrogenase	gnl|CDD|237552	PRK13903, murB, UDP-N-acetylmuramate dehydrogenase.	0
NZ_AP022614.1|WP_085272056.1|3510478_3511555_-|acyltransferase-family-protein	gnl|CDD|153249	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this suubgroup are such LPLATs as 2-acylglycerol O-acyltransferase (MGAT), and similar proteins.	4.57261e-41
NZ_AP022614.1|WP_139826018.1|3520036_3521257_-|sensor-histidine-kinase	gnl|CDD|274368	TIGR02966, Phosphate_regulon_sensor_protein_PhoR, phosphate regulon sensor kinase PhoR. Members of this protein family are the regulatory histidine kinase PhoR associated with the phosphate ABC transporter in most Proteobacteria. Related proteins from Gram-positive organisms are not included in this model. The phoR gene usually is adjacent to the response regulator phoB gene (TIGR02154). [Signal transduction, Two-component systems].	7.65987e-69
NZ_AP022614.1|WP_085271788.1|3528805_3529315_+|DUF2505-domain-containing-protein	gnl|CDD|378476	pfam10698, DUF2505, Protein of unknown function (DUF2505). Members of this family are all Actinobacteria. The function is not known.	4.93837e-45
NZ_AP022614.1|WP_085271794.1|3521408_3522158_-|phosphoglyceromutase	gnl|CDD|184519	PRK14120, gpmA, phosphoglyceromutase; Provisional.	1.52574e-180
NZ_AP022614.1|WP_085271797.1|3517077_3518094_-|Ppx/GppA-family-phosphatase	gnl|CDD|367122	pfam02541, Ppx-GppA, Ppx/GppA phosphatase family. This family consists of the N-terminal region of exopolyphosphatase (Ppx) EC:3.6.1.11 and guanosine pentaphosphate phospho-hydrolase (GppA) EC:3.6.1.40.	7.1154e-104
NZ_AP022614.1|WP_085271793.1|3522179_3522695_-|YbjN-domain-containing-protein	gnl|CDD|371210	pfam10722, YbjN, Putative bacterial sensory transduction regulator. YbjN is a putative sensory transduction regulator protein found in Proteobacteria. As it is a multi-copy suppressor of the coenzyme A-associated temperature sensitivity in temperature-sensitive mutant strains of Escherichia coli the suggestion is that it both helps CoA-A1 and possibly works as a general stabilizer for some other unstable proteins. This family was expanded to subsume other related families: DUF1790, DUF1821 and DUF2596.	2.10718e-21
NZ_AP022614.1|WP_085271802.1|3513035_3513293_-|helix-turn-helix-domain-containing-protein	gnl|CDD|200128	TIGR01764, Probable_excisionase, DNA binding domain, excisionase family. An excisionase, or Xis protein, is a small protein that binds and promotes excisive recombination; it is not enzymatically active. This model represents a number of putative excisionases and related proteins from temperate phage, plasmids, and transposons, as well as DNA binding domains of other proteins, such as a DNA modification methylase. This model identifies mostly small proteins and N-terminal regions of large proteins, but some proteins appear to have two copies. This domain appears similar, in both sequence and predicted secondary structure (PSIPRED) to the MerR family of transcriptional regulators (pfam00376). [Unknown function, General].	2.9847e-16
NZ_AP022614.1|WP_085271798.1|3516052_3517081_-|hypothetical-protein	gnl|CDD|237057	PRK12323, PRK12323, DNA polymerase III subunit gamma/tau.	0.00147329
NZ_AP022614.1|WP_085271801.1|3513433_3514321_-|pyrroline-5-carboxylate-reductase	gnl|CDD|237008	PRK11880, PRK11880, pyrroline-5-carboxylate reductase; Reviewed.	3.6145e-101
NZ_AP022614.1|WP_085271799.1|3515182_3516025_-|sugar-phosphate-isomerase/epimerase	gnl|CDD|224007	COG1082, IolE, Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism].	5.95206e-31
NZ_AP022614.1|WP_139826017.1|3526245_3527592_-|L,D-transpeptidase-family-protein	gnl|CDD|380079	pfam17964, Big_10, Bacterial Ig domain. This entry represents a bacterial Ig-like domain found associated with transpeptidase domains.	6.76507e-75
NZ_AP022614.1|WP_085271791.1|3524026_3525340_-|ROK-family-protein	gnl|CDD|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	2.31368e-37
NZ_AP022614.1|WP_085271790.1|3525512_3526262_+|SDR-family-oxidoreductase	gnl|CDD|226674	COG4221, COG4221, Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only].	3.8303e-90
NZ_AP022614.1|WP_085271787.1|3529337_3530168_+|carbon-nitrogen-hydrolase-family-protein	gnl|CDD|143605	cd07581, nitrilase_3, Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases). The nitrilase superfamily is comprised of nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes, which depend on a Glu-Lys-Cys catalytic triad. This superfamily has been classified in the literature based on global and structure based sequence analysis into thirteen different enzyme classes (referred to as 1-13). Class 13 represents proteins that at the time were difficult to place in a distinct similarity group; this subgroup represents either a new class or one that was included previously in class 13. Members of this superfamily generally form homomeric complexes, the basic building block of which is a homodimer.	1.01145e-118
NZ_AP022614.1|WP_085271792.1|3522691_3523966_-|D-inositol-3-phosphate-glycosyltransferase	gnl|CDD|132490	TIGR03449, mycothiol_MshA, D-inositol-3-phosphate glycosyltransferase. Members of this protein family, found exclusively in the Actinobacteria, are MshA, the glycosyltransferase of mycothiol biosynthesis. Mycothiol replaces glutathione in these species.	0

Protein sequences

>NZ_AP022614.1|WP_085271796.1|3518377_3519163_+|hypothetical-protein
MADSHPGPGQEVELDFAREWVEFYDPDNPEHLIAADLTWLLSRWTCVFGTPACHGTVAGRPDDGCCSHGAFLSDDDDRARLDDAVRQLSADDWQFREKGLSRKGYLELDEHDGQPQYRTRKHKDACIFLNRPGFPAGAGCALHIKAVELGVPPLTMKPDVCWQLPIRRSQEWVTRPDGTEILKTTVTEYDRRGWGSGGADLHWYCTGDPGAHVGATQVWESMADELTELLGAKAYAELAAMCKRRSKLGLVAVHPATRIAE
>NZ_AP022614.1|WP_085271797.1|3517077_3518094_-|Ppx/GppA-family-phosphatase
MRLGVLDVGSNTVHLLVVDAHRGGHPTPMSSTKATLRLAESIDGSGKLTKRGAEKLISTIDEFAKIADSSGCAELMAFATSAVRDAENSDDVLARVRKETGVELQVLDGVAESRLTFLAVRRWYGWSAGRIINLDIGGGSLEMSSGVDEEPEVALSLPLGAGRLTREWLPDDPPGRRRVAMLRDWLDAELSDASMTVLDAGAPDLAVATSKTFRSLARLTGAAPSAAGPRVKRTLTANGLRQLISFISRMTTADRAELEGVSAERAPQIVAGALVAEASMRALSIESVDICPWALREGLILRKLDSEADGTALMEPAKGDAGGSAVDRDGNRSRGDKS
>NZ_AP022614.1|WP_085271798.1|3516052_3517081_-|hypothetical-protein
MTGPHSDTDSTRPISVAELLARNGTIGAPAVTRRRRRRRGDSDAVTVAELTGEIPVIRDDEHHEHHEHRETGPDTATAVEAPAPAAEAHAPAAEAHAPAEAPAHDLAHEQENRSSTAYWSEPEPRWPKSPPQPHRASGPERSAYPLPQRRAEPDEKSDRPGQAAGAEDMSPDPVDAYADMPVDVMDSEVRDADLTAEDSAYVRSYLQGLDSTLANGHDLDGGGADWGIAAPSAKPRLADDQGGDAAEGRPAPGRFEALWRAGLVVFQSMLAVAFGAGLFVAFDQLWRWNSIVALVLSVLVILGLVVGVRVVRKTEDITSTLIAVAVGALITLGPLALSLQSG
>NZ_AP022614.1|WP_085271799.1|3515182_3516025_-|sugar-phosphate-isomerase/epimerase
MRPSIKVGLSTASVYPLRAEAAFEYAARLGYDGVELMVWSESVSQDIDAVEKLSRRYRVPVLSVHAPCLLISQRVWGANPIPKLERSVRAAEQLGAQTVVVHPPFRWQRRYAEGFSEQVMELEASSDVLVAVENMFPFRADRFFGAGQSRERMRKRGGGPGPAISAFAPSYDPLDGNHAHYTLDLSHTSTAGTDALDMAERMGAGLVHLHLCDGSGLPADEHLVPGRGTQPTAEVCQMLAGGHFAGHVILEVSTSSARSAGERETMLTQSLQFARTHLLR
>NZ_AP022614.1|WP_085271800.1|3514333_3515167_-|thioesterase-family-protein
MNALFTTAMTLREVEPCVYEGELDKRWTIGPKVHGGAMLALCANAARTACGGPSNGLEPVAVSANFLWAPDPGAMRLVTSVRKRGRRISVVDVELLQGERTAVHAVVNIGEPEHYPPGGPASPLLSANPVVDLMAPEPPDDIEPIGPGHPLGGLVHLGEGCDVRPLLSTMGPGTDGKPPMLQMWARPRDVAPDALFALMCGDLSAPVTFAVDRTGWAPTIQLTTFLRGLPADGWLRVVCTCMEIGHDWFDEDHIVVDSLGRIVAQSRQLALVPAARG
>NZ_AP022614.1|WP_085271801.1|3513433_3514321_-|pyrroline-5-carboxylate-reductase
MLSGMARIAIIGGGSIGEALLSGLLRAGRQTKDLVVVERIPERAKYLADEYSVRVTSVSDAVDNASFVVVAVKPADVESVMGELARAATAAGNDSAEQVFVTVAAGITLGYFESKLPAGTPVVRAMPNAAALVGAGVTALAKGRFVTAVQLEEVSALFDAVGGVLTVPEAQMDAVTALSGSGPAYFLLLVEALVDAGVAAGLNRQVATDLTTQTMAGAAAMLLERMEADGRPAAGEALGLRVDTAAAQLRATITSPGGTTAAALRELEKGGLRAAVDAAVQAAKKRSEQLRITSE
>NZ_AP022614.1|WP_085271802.1|3513035_3513293_-|helix-turn-helix-domain-containing-protein
MTSTNGPSARDSAGKGRDTSSVEGQQGRTQFLTVAEVAALMRVSKMTVYRLVHNGELPAVRVGRSFRVHAKAVHDMLETSYFDAG
>NZ_AP022614.1|WP_003402602.1|3512747_3512849_-|AURKAIP1/COX24-domain-containing-protein
MGSVIKKRRKRMSKKKHRKLLRRTRVQRRKLGK
>NZ_AP022614.1|WP_085271803.1|3511560_3512688_-|SDR-family-oxidoreductase
MDSSSGEGAAAGGTGSDAVHYPKVVLVTGACRFLGGYLTARLAQNPMIKGVIAVDAIAPSKDMLRRMGRAEFVRADIRNPFIAKVIRNGDVDTVVHAAAASYAPRSGGSAALKEINVMGAMQLFAACQKAPSVRRVVLKSTSEVYGSSAHDPVVFTEDSTSRRPLRGGFAKDSLDIEGYARGLGRRRPDIAVTILRLANMIGPAMDTTLSRYLAGPLVPTMFGRDARLQLLHEQDALGALERAAMAGKAGTFNIGADGIVMLSQAIRRAGRIPLPVPGFGVWALDSLRRANRYNEISREQFDYLSYGRVMDTTRMRTELGYQPKWTTAEAFDDYVRGRRLTPIIDPHRVRSLEGRAIALAQRWGSRSPIPWGGVR
>NZ_AP022614.1|WP_085272056.1|3510478_3511555_-|acyltransferase-family-protein
MVGETRANVIPLHTNRGRVAARRRADQRAESARQHPSLLSEPQGRASAEQIAAVVREIDERRRTAGTGGKPGSPEAPLNELAQRVAAVAGFLRQRLTGDYSVDEFGFDPHFNSAIVRPLLRFFFRSWFRVEVSGIENLPGDGPALVVANHAGVLPFDGLMLSVAVHDEHPAHRDIRLLAADMVFDLPLIGEAARKAGHTMACTTDAHRLLAGGELTAVFPEGYKGLGKRFEERYRLQRFGRGGFVTAALRTKAPIIPCSIIGSEEIYPMLTDVKLLARLFGLPYFPVTPLFPLAGPAGLVPLPSKWRITFGEPIYTNDYAASDAEDPMVTFELTDQVRETIQQTLYRMLAGRRNIFLG
>NZ_AP022614.1|WP_139826018.1|3520036_3521257_-|sensor-histidine-kinase
MTVFSALLLAGVLSVVALAAGVAAGRRLSSRAVQHRQQTTTEWSGITVAQMLQRIVALMPMGAAVVDSHRDVVYLNERARELGLVRDRQLDDQAWQAAQQALAGVVAEFDLRPAKRAPGRSGLSVHGQARLLSEEDRRFAVVFVHDQSDYARMEATRRDFVANVSHELKTPVGAMALLAEALLASADDSETVRRFAEKVLVEANRLGDMVAELIELSRLQGAERLPNVTEVEVDTVVSEAISRHKVAADNADIEIRTDSPAGLRVLGDETLLVTALANLVSNAIAYSPPGSPVSISRRRRGDNIEIAVTDRGIGIALEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHNGSIGVWSKPGTGSTFTLSIPAFKDGDEVNEPQRGREVRPSRPHREEELSR
>NZ_AP022614.1|WP_085271794.1|3521408_3522158_-|phosphoglyceromutase
MGETATLVLLRHGESEWNASNQFTGWVDVDLTEKGRAEAVRSGELMAESDLLPDVLYTSLLRRAITTAHLALDTADRLWIPVRRSWRLNERHYGALQGLNKAETKARYGDEQFMAWRRSYDTPPPPIERGSRYSQDSDPRYANIGGGPLTECLADVVARFLPYFTDVVVPDLRSGKTVLMVAHGNSLRALVKYLDGMSDEAVVDLNIPTGIPLRYDLDGDLRPVVPGGTYLDPEAAAVGAAAVAGQGRG
>NZ_AP022614.1|WP_085271793.1|3522179_3522695_-|YbjN-domain-containing-protein
MNSTVEAVIEGALQASDLNYSKQAGAHGGPSGLVVELPGERKLKTNTILSIGEHSVRVEAFVCRKPDENHEGVYRFLLKRNRRLYGVAYTLDNVGDIYLVGRMSLASVDADEIDRVLGQVLEAVDSDFNTLLELGFRSSIQKEWEWRVSRGESLKNLQAFAHLIDEDDQDD
>NZ_AP022614.1|WP_085271792.1|3522691_3523966_-|D-inositol-3-phosphate-glycosyltransferase
MRHDDVFRLNDPRRVAVLAVHTSPLAQPGTGDAGGMNVYVLQTALHLARRGIEVEIFTRATASADPPVARVAPRVLVRNVVAGPFEGLDKYDLPTQLCAFAAGVLRAEASHEPGYYDIVHSHYWLSGQVGWLARDRWAVPLVHTAHTLAAVKNAALADGDAPEPPLRTVGEQQVVDEADRLIVNTADEAKQLISLHNADPARIDVVHPGVDLETFRPGDRRAARAALGLPPGEKVVAFVGRIQPLKAPDIVLRAAAKLPGVRVVVAGGPSGSGRSSPDGLVRLAGELGIAARVTFLPPQSRENLTTLFRAADLVAVPSYSESFGLVALEAQACGTPVVAAAVGGLPVAVRDGVTGTLVPGHDVEHWAHALDRLLRLRAPQAGAMSRAAAEHASKFSWDNTTDALLASYRRAIGDFRAERQGMGA
>NZ_AP022614.1|WP_085271791.1|3524026_3525340_-|ROK-family-protein
MRSNTLTPSHRSPNRAAGQTGNRRSRPQILPPALHIPDSAAASVFRAVRLHGPVGRDVIARVTSLSIATVNRQVIALLDAGLLRERADLAVSGAIGRPRVPVEINHEPFVTLGIHIGAKTTSIVATDLFGRTLDTVETPTPLSPAGPALASLAESAGRYLQRWHRRRPLWVGVAIGGTVDGATGHVDHPRLGWRQAPVGPVLADALHLPVSVASHVDAMAGAELLLGMRRFRPSSPTSLYVYARETVGYALVIGGRVHCPASGPGTIATLPAYSELLGGTGQLESTVSDEAVLAAARRLKVVPGGPAGRATTGVTDLVRVARAGNPQAQELLAERARVLGEAVALLRDMLNPDELVVGGQAFTEYPEAMEHVERAFAARSVLSPRDIRVTAFGNRVQEAGAGTVSLGGLYANPLGAMRRAGALDAPLRDVPADESSA
>NZ_AP022614.1|WP_085271790.1|3525512_3526262_+|SDR-family-oxidoreductase
MVAIGRNERVAVVTGASSGIGEATARTLAAQGFHVVAVARRAQRIQALADEIGGTAIVADVTDDAAVDSLSAALGRVDVLVNNAGGARGLEFVADADLEHWRWMWETNVLGTLRVTRALLPRLIDSGDGLIVTVTSIAALETYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPGAVETEFSLVRFDGDEKRADDVYTGITPLTAGDIAEVIGFVASRPSHVDLDLVVIRPRDQASASRFNRRG
>NZ_AP022614.1|WP_139826017.1|3526245_3527592_-|L,D-transpeptidase-family-protein
MDVVTTPSAPPPINRRVALATLGLGVFAPGLLAACAGTATKQAEKKEPPAPQLTYQPALNTPAADNVVPIAPISVQVSEGWFQHVTLTNSSGKAVAGTFNQDRTVYTTTEPLGYDSTYTWSGAAVGHNGKAVPVSGKFTTVSPTKKVGGQFQLADGQTVGVAAPVIIQFDSTISDKAAVEKALAVTTDPPVEGSWAWLPDESQGARVHWRPREYYPAGTTVNVDAKLYGLPFGDGAYGADDISLRIQIGRRQVVKAEVSSHRIQVVTDAGVIMDFPCSYGEADKARNVTRNGIHVVTEKYADFYMSNPAAGYTNAHERWAVRISNNGEFIHANPSSAGAQGNSNVTNGCINLSTGDAEEYYHSAIYGDPVEVTGSTIQLSYADGDIWDWAVDWDTWVAMSALPPPKAHAPSTQIPVTAPVTPTDAPTLSGTPTTTTTTSSSPVPSPGG
>NZ_AP022614.1|WP_085271789.1|3527663_3528779_-|UDP-N-acetylmuramate-dehydrogenase
MRPSAAGRLHAGAQVAEQAPLAPLTTLRIGPVARRLITCTSTDHVIAVLRELDGRDDGVDEAVLVFAGGSNVVLADSLTGVTAVRLANGGITVDGNLLRAEAGAVWDDVVVRSIEHGLGGLECLSGIPGSAGATPVQNVGAYGAEVSDCITRVRVLERDSGTVRWVPGSELEFGYRTSIFKHGEAVGLGPARVVLEVEFALDAAGRSAPLRYGELADALDVSAGERAEPRAVREAVLRLRGRKGMVLDAADHDTWSVGSFFTNPVVAPDVCERLADTIDGPVPHYPAPDGVKLAAGWLVERAGFAKGYPEPDPGGLEARCRLSTKHALALTNRGGANTEDVLALARLIRTRVHDVFGITLQPEPVLLGCRL
>NZ_AP022614.1|WP_085271788.1|3528805_3529315_+|DUF2505-domain-containing-protein
MPHSFELSADYEDNAETLYQAFREEDYWLARLADIPVDEAKLDSMRIGGDGTVDVVTLQVVRSHNLHALVKQLHRGDLCVRREETWDPFADGVARGLIAGTIVGTPVDVSGSAELSSTEPGGARLTYRITVKVRIPIIGGKVEKLIGTHLGELVSREQRLTADWIAANA
>NZ_AP022614.1|WP_085271787.1|3529337_3530168_+|carbon-nitrogen-hydrolase-family-protein
MRIALAQILSGSDPAANLELVREYTGRAADEGATLVVFPEATMCRFGVPLAPIAEPVDGPWADGVRRIAADAGVTVIAGMFCPAGDGRVTNTLIAAGPGRPSGPDAHYDKIHLYDAFGFAESRTVAPGHQPVVITVDDVEVGLSVCYDIRFPALYTELARRGAQLIVVCASWGSGPGKLEQWTLLARARALDSMSYVAAAGQADPGEAVTSSGAPTGVGGSLVASPLGQVVASAGSQPQLVVADIDVSTVSQARDSIAVLRNHSHFAQIDRAESVG

Crispr_ID: NZ_AP022614_6

• CRISPR_ID: NZ_AP022614_6
• CRISPR_location: 4402981-4403058
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_AP022614_6

Consensus_repeat	Method
ATGACCCGTGCCGGCGACGATGCAG	CRISPRCasFinder

spacers of NZ_AP022614_6

>6.1|4403006|28|NZ_AP022614|CRISPRCasFinder
CGCGAAGCAATGAGGAGGAGCGGCACCA

CRISPR arrays and Neighbor proteins around NZ_AP022614_6

CRISPR arrays

The CRISPR arrays of NZ_AP022614_6

>merge|NZ_AP022614|6|4402981-4403058|CRISPRCasFinder
ATGACCCGTGCCGGCGACGATGCAGCGCGAAGCAATGAGGAGGAGCGGCACCAATGACCCGTGCCGGCGACGATGCAG

>NZ_AP022614|6|6|4402981-4403058|CRISPRCasFinder
ATGACCCGTGCCGGCGACGATGCAG	CGCGAAGCAATGAGGAGGAGCGGCACCA
ATGACCCGTGCCGGCGACGATGCAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP022614.1|WP_085270809.1|4394026_4394794_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl|CDD|223282
NZ_AP022614.1|WP_085270820.1|4408806_4409838_+|esterase-family-protein	unknown	unknown	gnl|CDD|223700
NZ_AP022614.1|WP_085270808.1|4392331_4393882_-|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|225130
NZ_AP022614.1|WP_085270816.1|4403110_4405021_+|glycosyltransferase	unknown	unknown	gnl|CDD|375472
NZ_AP022614.1|WP_163670883.1|4406576_4408442_+|hypothetical-protein	unknown	unknown	unknown
NZ_AP022614.1|WP_085270807.1|4392002_4392335_-|hypothetical-protein	unknown	unknown	unknown
NZ_AP022614.1|WP_085270814.1|4400554_4401487_-|PirG	unknown	unknown	gnl|CDD|237537
NZ_AP022614.1|WP_085270818.1|4405564_4406473_+|decaprenyl-phosphate-phosphoribosyltransferase	unknown	unknown	gnl|CDD|237058
NZ_AP022614.1|WP_139825920.1|4396340_4397168_+|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl|CDD|369792
NZ_AP022614.1|WP_163670985.1|4414289_4419593_+|acyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|238429
NZ_AP022614.1|WP_085270806.1|4390449_4392006_+|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|224154
NZ_AP022614.1|WP_085270817.1|4405013_4405568_+|phosphatase-PAP2-family-protein	unknown	unknown	gnl|CDD|239489
NZ_AP022614.1|WP_085270810.1|4395559_4396345_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl|CDD|153251
NZ_AP022614.1|WP_085270825.1|4419592_4421167_+|acyl-CoA-carboxylase-subunit-beta	unknown	unknown	gnl|CDD|227136
NZ_AP022614.1|WP_085270822.1|4411045_4412056_+|cutinase-family-protein	unknown	unknown	gnl|CDD|366455
NZ_AP022614.1|WP_085270821.1|4409996_4410914_+|esterase-family-protein	unknown	unknown	gnl|CDD|223700
NZ_AP022614.1|WP_085270823.1|4412310_4414203_+|AMP-binding-protein	unknown	unknown	gnl|CDD|181109
NZ_AP022614.1|WP_085270812.1|4397171_4398674_-|PE-family-protein	unknown	unknown	gnl|CDD|376422
NZ_AP022614.1|WP_085270888.1|4394801_4395545_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl|CDD|153251
NZ_AP022614.1|WP_085270813.1|4398764_4400393_-|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl|CDD|227766

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP022614.1|WP_085270809.1|4394026_4394794_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase	gnl|CDD|223282	COG0204, PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism].	8.30383e-50
NZ_AP022614.1|WP_085270820.1|4408806_4409838_+|esterase-family-protein	gnl|CDD|223700	COG0627, COG0627, Predicted esterase [General function prediction only].	2.0246e-88
NZ_AP022614.1|WP_085270808.1|4392331_4393882_-|MBL-fold-metallo-hydrolase	gnl|CDD|225130	COG2220, COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only].	1.45672e-25
NZ_AP022614.1|WP_085270816.1|4403110_4405021_+|glycosyltransferase	gnl|CDD|375472	pfam17994, Glft2_N, Galactofuranosyltransferase 2 N-terminal. This is the N-terminal beta-barrel domain found in the polymerizing galactofuranosyltransferase GlfT2 (Rv3808c). This enzyme synthesizes the bulk of the galactan portion of the mycolyl-arabinogalactan complex, which is the largest component of the mycobacterial cell wall such as in Mycobacterium tuberculosis. The N-terminal domain contains two short helices preceding a 10-stranded beta-sandwich with jelly roll topology.	7.65568e-86
NZ_AP022614.1|WP_085270822.1|4411045_4412056_+|cutinase-family-protein	gnl|CDD|366455	pfam01083, Cutinase, Cutinase.	5.97583e-09
NZ_AP022614.1|WP_085270814.1|4400554_4401487_-|PirG	gnl|CDD|237537	PRK13875, PRK13875, conjugal transfer protein TrbL; Provisional.	3.90603e-05
NZ_AP022614.1|WP_085270818.1|4405564_4406473_+|decaprenyl-phosphate-phosphoribosyltransferase	gnl|CDD|237058	PRK12324, PRK12324, decaprenyl-phosphate phosphoribosyltransferase.	1.53006e-144
NZ_AP022614.1|WP_139825920.1|4396340_4397168_+|Cof-type-HAD-IIB-family-hydrolase	gnl|CDD|369792	pfam08282, Hydrolase_3, haloacid dehalogenase-like hydrolase. This family contains haloacid dehalogenase-like hydrolase enzymes.	1.2824e-77
NZ_AP022614.1|WP_163670985.1|4414289_4419593_+|acyltransferase-domain-containing-protein	gnl|CDD|238429	cd00833, PKS, polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or more large multifunctional proteins and iterative type II PKSs, complexes of several monofunctional subunits.	0
NZ_AP022614.1|WP_085270806.1|4390449_4392006_+|NAD(P)/FAD-dependent-oxidoreductase	gnl|CDD|224154	COG1233, COG1233, Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	1.13426e-90
NZ_AP022614.1|WP_085270817.1|4405013_4405568_+|phosphatase-PAP2-family-protein	gnl|CDD|239489	cd03395, PAP2_like_4, PAP2_like_4 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	1.47115e-14
NZ_AP022614.1|WP_085270810.1|4395559_4396345_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase	gnl|CDD|153251	cd07989, LPLAT_AGPAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.	2.12743e-42
NZ_AP022614.1|WP_085270825.1|4419592_4421167_+|acyl-CoA-carboxylase-subunit-beta	gnl|CDD|227136	COG4799, COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism].	0
NZ_AP022614.1|WP_085270821.1|4409996_4410914_+|esterase-family-protein	gnl|CDD|223700	COG0627, COG0627, Predicted esterase [General function prediction only].	1.77546e-64
NZ_AP022614.1|WP_085270823.1|4412310_4414203_+|AMP-binding-protein	gnl|CDD|181109	PRK07769, PRK07769, long-chain-fatty-acid--CoA ligase; Validated.	0
NZ_AP022614.1|WP_085270812.1|4397171_4398674_-|PE-family-protein	gnl|CDD|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	1.88537e-26
NZ_AP022614.1|WP_085270888.1|4394801_4395545_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase	gnl|CDD|153251	cd07989, LPLAT_AGPAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.	1.28529e-44
NZ_AP022614.1|WP_085270813.1|4398764_4400393_-|N-acetylmuramoyl-L-alanine-amidase	gnl|CDD|227766	COG5479, COG5479, Uncharacterized protein potentially involved in peptidoglycan biosynthesis [Cell envelope biogenesis, outer membrane].	6.20805e-115

Protein sequences

>NZ_AP022614.1|WP_085270814.1|4400554_4401487_-|PirG
MSAVAAVAVASPCAYFLVYESTSAGKQPEHHEFKQAAVMTDLPGELMGALTQGLSQFGINMPPIPALSGGGASTTGLTGPGLGTPGLGTTGLTSPGLTSPGLTSPGLTSPGLASPGLSPTTPGLTAPGALPTTPGVGGLTTPGAGLNPALTSPAGGLGTPAAGEVPITTPAALDPGADGTYPILGDPSTLGGGGGGGGNGGGGLINDVMQAANQLGAGQAIDLLKGLVMPAITQSMQGGAGAPGALPGAAGALPGALPGAAGALPGAAGALPHAAAALPGAAGALPGAAGALPGAAGAAAPAAAAPLPPV
>NZ_AP022614.1|WP_085270813.1|4398764_4400393_-|N-acetylmuramoyl-L-alanine-amidase
MLMTAVIATVVIVSWMTGTARDRDPASGPQRRDTLLAEQPLVGLGGGVTVRELTQDTPFSLVALTGDLAGTSTRVRAKRADGSWGPWYQTEYETAAPDSAAPGAPAGALEGPRSTDPVFVGTTTTVQVAVTRPVDAPLTQPPAAPAASEGLGYRPASRERPFGQNISAILISPPQAPPKQKWTPPAGVLMPGQAPPIISRAEWGADESLRCGSPQYDNGIRAAVVHHTAGSNDYSPLESAGIVKAIYTYHSKTLGWCDIAYNALVDKYGQVFEGSAGGLTKAVEGFHTGGFNRNTWGVAMIGNFDDVPPTPIQLRMVGRLLGWRLGLDGVDPKGTVALESAGSHYTVFPAGAVATLPTIFTHRDVGNTDCPGNAAYALMDEIRDIASHVNDPPEELLKALEGGAIYQHWIDMGGMKSYLGAPTSPEDDAEGSGGVARYVTFAKGAMYWSPETGPQPVTGALYDAWASLSYERGPLGLPTSAEIQEPLQITQNFQHGTLNYERLTGNVTQVVDGITTPLSTEPPEGPTVPAEHFSLPSHPGTA
>NZ_AP022614.1|WP_085270812.1|4397171_4398674_-|PE-family-protein
MSFVLTAPEAVTDAAGNLAGIGTTLERAAAAAAGPTTGIAAPAADEVSVAISRVFGTYGQQFQALSARAAAFHDGFVGLLNGSAAAYVGTEAANTEQALMAAVEAPAAALPVGAYGQLVANTTANLQSLYRAWAADPLPLLRQIVANQQVYARQFVAALAGAIANLPAELANLPAAVQSGVQGLLTFDAAYYVQQFVATQVGFAQTFASSLNDALTGIVAGLPGLQSGLQAAYQAVLAGNYYGAVQDVAQAFANLLVTGFNPGTVTTSLLTPLTNPTVVATVNPTILGPLGDLFTIANLPGQEAQYLTNLIPPSVFRQMAQNLTNVLDALSIPSISATVTLPLLAPTTGSLSAFFGLPLVLTYAVMGAPISALNGLATSATAVQQALLAGNGVGALGALFDAPAAIANGFLNSDTLVDFTIPVPVTLPAPFPSFNVPITLHLPFDGILVPPHPITATIDPSALGFGPTPVTIFGTPFMGLVPLLVNYLPEQLAAVIVPAA
>NZ_AP022614.1|WP_139825920.1|4396340_4397168_+|Cof-type-HAD-IIB-family-hydrolase
MEPAMTKPALIACDVDGTLFDENETITPRTRDAVLAAVAAGATFVVATGRPPRWIRPVVEALGFAPMAVCANGAVIYDSATDRVVSARTLSVDTLAELAELATRVIPGAGLAVERIGERAHDTATPQFISSPGYEHAWLNPDNTEVSIEDLLSAPAIKLLIRRAGARSADMAAELAKHVGIEGDITYSTNNGLVEIVPLGISKATGVDELARPLEIGSDEVVAFGDMPNDLPMLLWAGHGVAMGNAHPEVMAAADEVTASNSDDGVGRVLERWWV
>NZ_AP022614.1|WP_085270810.1|4395559_4396345_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase
MAEAFYRLGELIVPPLVAMQGTKITFEGLENIPERGGALLAQNHTSYLDWLPTLLGVRERGRRAYFMIKAEMAEVKAADYVIRHARLIPVDRTAGHEAFDLAVRRMRQGELIGMHPEATISRSFELREFKTGAARMAVEAGVPIVPVIVWGAHRIWPKDHPKKVFRNKVPITVAAGRPLPPHGTVEQLNAALREQMNALLYRVQAEYPHPPGEFWVPRRLGGSAPTQDDSRAIRLAELQERMKRHGTDGVTRPGQSQSGLH
>NZ_AP022614.1|WP_085270888.1|4394801_4395545_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase
MVEPTFRSLEILAQLVVAATGTRITYRGVENIPERGGAVVAINHTSYVDWLPAALAVHRRRRRLRFMIKAEMQRVRAVDFLIRHTRTIPVDRRAGAGAYAVAVQRLREGELVGVYPEATISRSFELKGFKTGASRMAIEAGVPIVPVIVWGAQRIWTKDHPRKLGRTKVPITVQVGAPLRPAADLAQTDAALRESMTTLLHQVQQHYPRPSGAYWVPHRLGGGAPTLEQAARIEADEAASRAPRRPE
>NZ_AP022614.1|WP_085270809.1|4394026_4394794_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase
MEPVYGTVIALARLIWRIQGLKITVSGVENLPESGGAVIAINHTGYLDFTFAGLPAFRQGRGRKVRFMAKQEVFDSKITGPLMRSLRHISVDRQEGAASYEAAVRNLKDGELVGVYPEATISRSFEIKEFKSGAARMAVEAGVPIVPVIVWGAQRIWTKGHPKKLFRPKVPITVLVGERIEPTLGTAELNALLHSRMQHLLERAQEMYGPHPAGEYWVPRRLGGGAPSLAEAARMDAEDAAARAARRAQAADPPE
>NZ_AP022614.1|WP_085270808.1|4392331_4393882_-|MBL-fold-metallo-hydrolase
MQVTSVGHAGFLIETPAGSILCDPWVNPAYFASWFPFPDNSALDWDALGDCDFLYVSHLHKDHFDAKNLARHVNKDAVVLLPDFPVPDLRNELQLLGFHRFFETTSGVRHRVAGPGGDLDVMILALRAPADGPIGDSALVVSDGVTTAFNMNDARPVDLDVLDAEFGHIDVHMLQYSGAIWYPMVYDMPERAKESFGVQKRQRQMDRARQYIAQVGASWVVPSAGPPCFLDPELRHLNDDHGDPANIFPDQMVFLEQMRAHGHERGLLMMPGSAADFTGSTLNSLTHPLPTDEVEAIFTTGKSAYIADYAERMAPVLAAERASWAPAGGEPLLEPLRALFEPIMLASDEICDGIGYPVELVLGQQTVVLDFPKRTVRERVPDERVRYGFAIAPELVRTVLRDHEPDWVNTIFLSTRFTAWRVGGYNEYLYTFFKCLTDERIAYADGWFAETHDDSASVTMDGWQIQRRCPHLKADLSKFGVVEGNTLTCNLHGWQWRLDDGHCLTARGHQLRSARA
>NZ_AP022614.1|WP_085270807.1|4392002_4392335_-|hypothetical-protein
MNATYDDGLIALDRAAITLRRYHFPSGTSKVIALGSIRGYKSERLGFFAQRLRIWGSSDLRRWLPLDIGRPFKSTLITLDVPGTWPRPACTPARPDEFTALLDELLGERG
>NZ_AP022614.1|WP_085270806.1|4390449_4392006_+|NAD(P)/FAD-dependent-oxidoreductase
MADFDAIVIGAGHNGLAAAVVLQKAGLRTVCLDAKLYAGGMASTVELFDGYRFEIAGSVQFPTSSVVVEALGLDTLPTIDLDVMSVALRGVGDDPLVQYSDPIKLFTHLNEVHGADAVNGMAGLMAWSQAPTRALGRFEAGAPPKTFDEMYACATNEFERSAIDDMLFGSVTDVLDRYLPDREKHGALRGSMTVLAVNTLYRGPATPGSAAALAFGLGVPDGDTMQMKKLRGGIGALTAHLCDLLESLGGEVRLRTKVTEIVVSDGRVTGVRTEAGDTFNAPVVVSGIAPDVTLNEMIDPAALPADIRERYARIDHRGSYLQMHFALEEAPAFAAPYEALNEPAMQASIGLFCTPEEVQRQWEDCRRGIVPADPTVVLQIPSQNDPGLAPEGKHAASAFALWFPIEGGADYGQAKVEMGQRVIDKITRLAPNFESSIIRHTTFTPRHMGVMFGAPGGDYCHGLLNADQIGPNRPGPKGFVGQPIPISGLYLGSAGCHGGPGITFIPGYNAGRAALEDR
>NZ_AP022614.1|WP_085270816.1|4403110_4405021_+|glycosyltransferase
MTAVSLLSRIILPRPGEPLDVRKLYLEESTTNARRAHATSRTSLQIGAESEVSFATYFNAFPASYWRRWSICTSVVLRVEVTGAGRVDLYRTKATGARIFVEGRQFSGAEDEAQVVEVEVGLQPFEDGGWVWFDITTDTKVTLLSGGWYATGTPPVKANIAVGIPTFNRPADCANALAALTADPLVDEVIGAVIVPDQGVRKVRDHPRFPEAAKRLGNRLTLCDQPNLGGSGGYSRVMYEALKNTDCQQILFMDDDIRIEPDSILRVLAMHRFAKSPMLVGGQMLNLQEPSHLHIMGEVVDQSNFMWTAAPHAEYDHDFAVYPLNDKNDRSKLLHRRIDVDFNGWWTCMIPRQVAEEVGQPLPLFIKWDDAEYGLRAAEHGYPTVTLPGAAIWHMAWSDKDDAIDWQAYFHLRNRLVVAALHWDGDVTGLVRSHLKATLKHLACLEYSTVAIQNRAIDDFLAGPEHIFSILESALPEVHRMRKQYPDAVVLPAASELPSPVYQSKAMKPPVNPFSIGYRLARGILHNMTKADPDHHRRPEFNVPTQDARWFRLCTVDGVTVTTADGCGVVYRQRNRAKMMSLLLASLRRQRQLTGRFDEMRKVYRDALPVLSSTQKWETALLPGPEDKAREKTQHA
>NZ_AP022614.1|WP_085270817.1|4405013_4405568_+|phosphatase-PAP2-family-protein
MPDASVSEAPRGEVAALVAVQSALAGRPGTLAVARGLSYFGEHSIGWVAAAILGAALLPGRRRAFLVAGAGAFAAHAAAVAVKRVVRRRRPHHPAVAVHVGTPSRLSFPSAHASSTTAAAILLGRAAGLGGLPLAAVLVPPMAISRMLLGVHYPSDVAVGVALGAGVAEITGRAARGLEGSAAQ
>NZ_AP022614.1|WP_085270818.1|4405564_4406473_+|decaprenyl-phosphate-phosphoribosyltransferase
MSEGVVTGPPGNLIAGVVKAIRPRQWVKNVIVLAAPLAALGGPIRYDYAEVLTKVSGAFVVFCLAASSIYLVNDVRDIAADREHPTKRYRPIAAGVVPEWLAYALAVVLAAASLAISWWLAPNLALVIAVYLGMQLAYCFGLKHQAVMDICIVSSAYLIRAIAGGAATKIPLSQWFLLFVAFGSLFMVAGKRYAELQVAERTGAAIRKALESYTSTYLRFVWTMSATAVVLCYGLWAFERDRHSGSWFAVSMVPFTIAILRYAVDVDGGLAGEPEDIALRDRVLQLLAVAWIVTVGAAVAFG
>NZ_AP022614.1|WP_163670883.1|4406576_4408442_+|hypothetical-protein
MRVSLWIGVATVATLFAWGAWQRRWIADDGLIVLRTVRNLLAGNGPVFNEGERVEANTSTAWTYLMYAGSWVGGPMRMEYVALALALLLSVLGVALLMLGAARLYAPSLRLRKAVMLPAGAFAYIALPPARDFATSGLETGLTLAYLGLLWWMMVCWGQPVRNRPDSPWFLGALAFVAGLSVLVRPDLALMGGLALIMMLIAARTWRRRGLVVLAGGLLPVAYEIFRMGYYGLLVPGTALAKDAAGDKWSQGMVYLSNFDAPYAVWVPALLLVPLGVLMVFARRRPSFLRPALAPNYGRIARAVQSPPAVVAFVLVSGLVQALYWIRQGGDFMHGRVLLAPLFCLLAPVAVIPVPIPDGQDYSRETGYWVAGAAGVLWLGVAGWSLWAANSPGMGDDATHVTYSGIVDERRFYAQATGHAHPLTAADYLGYPRMAAILAALDNTPDGALLLPSGNYIQWDLVPMLQPPPGSPPQKPQHTVFFTNLGMVGMNVGLDVRVIDQIGLANPLAQHTERLKHGRIGHDKNLFPDWVIADGPWVKTYPGIPGYLDQQWVAEAVAALKCPETQAVLGSVRAPLTVHRFLSNLLHSYDFTSYRIDRVPLYELARCGLPLPDTVPPPPRE
>NZ_AP022614.1|WP_085270820.1|4408806_4409838_+|esterase-family-protein
MTLVDRLRSAAAVMPRRLAVAAVGAALLSGLIGAVGGSATAGAFSRPGLPVEYLQVPSAAMGRDIKVQFQSGGANAPALYLLDGMRAQDDYNGWDINTPAFEWYNQSGIATVMPVGGQSSFYSDWYKPACGKAGCTTYKWETFLTSELPQYLSANKQVKPTGSAVVGLSMAGSSALILSAYHPDQFIYAGSLSALLDPSQGMGPSLIGLAMGDAGGYKAADMWGPSSDPAWARNDPSLQVGKLVANNTRIWVYCGNGKPSDLGGDNLPAKFLEGFVRTSNLKFQDAYNAAGGHNAVWNFDANGTHDWPYWGAQLQAMKPDLQSTLGATPGAGPATAAPTNDGT
>NZ_AP022614.1|WP_085270821.1|4409996_4410914_+|esterase-family-protein
MRVGRRGAAAVLRAICGAVLAVVFGGVTVTAGIPGAARAAGYESLMVPSAAMGRDIPVAFLAGGPHAVYLLDPFDAGPDVSNWVTAGNAMNTLAGKGISVVAPAGGAYSMYTNWEQDGSKQWDTFLSSELPDWLAANKGLAPGGHAAVGAAQGGYAAMALAAFHPDRFGFAGSMSGFLYPSSTNYNGAILAGLQQFGGVDGNGMWGAPQLGRWKWHDPYVHASLLAQNNTRVWVYSPTNDGASDPAAMIGQASAAMGSAREFYQQYRSVGGHNGHFDLPGGGDNGWGSWSGQLGAMSGDIVGAIR
>NZ_AP022614.1|WP_085270822.1|4411045_4412056_+|cutinase-family-protein
MTTKSRRRRHRILAWVAALSVAGVVLLVVALAAVLLRSHEAPPSAVPPGVLPPSSTTTHPHKPRPASQDSSCPDVEVIAVPGTWESSPQDDPRNPTQFPNALLLKVTGPLSSQFPGSRMRTYTVAYTAQFHNPLSGDTQMSYNQSRAEGTRALVQAMTDINNKCPLTSYVLMGFSQGAVIAGDVASDIGNGRGPVDDDLVLGVTLIADGRRQQGVGNDVGPNPPGQGAEVTLQEVPVLSGLGLTMTGPRPGGFGALNDKTNEICAPGDLICAAPEEAFSVANLPNTLNTLAGGAGQPVHALYATTQCWSLDGQPATDWTLNWAQGLVAGAPHPKHG
>NZ_AP022614.1|WP_085270823.1|4412310_4414203_+|AMP-binding-protein
MVYHNPFIVNGRITFPDNTNLVLHVEKWARVRGDRLAYRFLDFSTERDGIARDIVWRDFSMRNRAVGARLQQVTKPGDRIAILCPQNLDYLIAFFGALYAGRIAVPLFDPSEPGHVGRLHAVLDDCAPSTILTTTEAAEGVRKFIRARSAKERPRVIAVDAVPDEVASTWQPPEATEETIAYLQYTSGSTRTPTGVQISQLNLPTNVLQVLVALQGTEGDRGCSWLPFFHDMGLITALLSPVLGHDFTFMTPAAFVRRPGRWIRELARKPGETGGVFSAAPNFAFEHAAVRGLPRDDEPPLDLSNVKGILNGSEPVSPASMRKFYEAFAPYGLQETAIKPSYGLAEATLFVSTTPMNEKPRVIHVDRDQLNNQRFVEVAADAPNAVAQVSAGEVGVDEWAVIVDPESASELPDGQIGEIWLHGKNLGLGYWGKEEETTDVFKNILKSRVAASHAEGAADDGLWVRTGDYGVYHDGHLYIAGRIKDLVIVDGRNHYPQDLEYSAQEASRALRTGYVAAFSVPANQLPQEVFDNPHVGLKYDAEDSSEQLVIVAERAAGTHKLDYQPIADDIRAAIAVQHGVTVRDLLLVQAGTIPRTSSGKIGRRACRAAYLDGSLRSGVGSPTAFASATD
>NZ_AP022614.1|WP_163670985.1|4414289_4419593_+|acyltransferase-domain-containing-protein
MTVPEMRQWLRNYVAKCTGQSPDSIDESVPMVELGMSSRDAVAMAADIEDLTGVTLSVAVAFQHPTIESLATRIVEGEPEADTSLDGNTDWTRKGPAERVDIAIVGLSTRFPGDMNTPDEMWQALVEGRDAITDLPEGRWSEFLDEPRLADRMVNAQTRGGYLKDIKGFDSEFFAVAKTEADNIDPQQRMALELTWEALEYARIPASSLRGKAVGVYVGVSNNDYAMMAVSDPTTAHPYAITGTATSIIANRVSYFYDFRGPSVAVDTACSSSLVAVHQAVQALRNGECDAAVAGGVNALITPAVTLGFDEIGAVLSPDGRIKSFSSDADGYIRSEGAGMLVLKRVDDARRDGDQILAVIAGSAINHDGRSNGLIAPNQDAQADVLRRAYKDAGIDPRNVDYIEAHGTGTVLGDPIEAEALGRIVGRGRPADRPALLGAVKSNIGHLESAAGVASMAKVVLALQHDKLPPSINFAGPSPYIDWDATHLKVVDTATDWPRYGGYALAGVSSFGFGGANAHVVVREVLPRDVVEKEPAPESPAAAEAEPAQAPSPGTFEGHSLRFDDFGNIITDTPAAEEEYELPGVTEEALRLKEIALEELAAKEAAEPTRPLIPLAVSAFLTSRKKAAAAELADWMDSPEGRASSLEAIGRSLSRRNHGRSRAVVLAHDHDEAIKGLRAVAEGKQRPGVFSADGPVTSGPVWAMAGFGAQHRKMGKNLYLRNDVFAEWIEKVDALIQDERGYSVLELILDDSHEYGIETSNVVIFAIQIALGELLKHHGAKPAAVIGQSLGEPASAYFSGGLSLADATRVICSRSHLMGEGEAMLFGEYIRFMALVEYSADELKTVFADFPGLEVCVYAAPSQTVIGGPPEQIDAIVARAEAEGRFARKLQTKGAGHTSQMDPLLGEFSAELQGIHPLSPTTGIFSTVHEGSFVKPGSDPIHDVAYWVKGMRHSVYFTHGVRNAVDSGYTTFLELAPNPVALMQIGLTTAAAGLPDAQLIPTLAKKQDDVESMISAMAQLYVYGHDLDIWTLFTRRSADRFDPQDYANIPPTRFKRKDHWLQVSFSAGSSAVIMPGAHVALPDGRHVWEYAPRIFTGLEATDLEALVKSAAAEVLEDAQLTASEVRAVPPQGSALVTTLTRHPGGASVQVHARVGESFTLVYDALVARAGAQSVLPAALGAGAGIAAGLPAAPAVEAQAPTPDRGAETVQDSLTSRYLPSDTARWSPDSGETIGERLGMIVGVAMGYEPEDLPWEVPLVELGLDSLMAVRIKNRVEYDFDLPPIQLTAVRDANLYNVEKLIEYAVEHRDEVSQLHEYQQTHTPEEVAKAQAELISGATPATAAAPAPDPQAEPQTQPQPASDIPVPPPPTDPSGPSGSTNGAGQPNLKAAADALNQEAIAKALNSDVPPRDAAERVTFATWAIVTGKSPGGIFNPLPRLDQATAAKMATRLSERAEGPITAEDVLTSQNIEALADKVRGYLEAGELDGFVRTIRAPQNDSQVPVFVFHPAGGSTVVYEPLLNRLPADTPMYGLERVEGTVQERAAQYVPKLLEINKDKPFVLVGWSLGGALAYACAIGLKRMGADVAFVGMIDTVRAGEEIPQTKEETRKRWDRYAKFAERTFNVEIPAIPYEQLEELDDEGQVKFVLDVVQQSGVQIPGGIVEHQRTSYLDNRALETVEIEPYDGHVTLYMADRYHDDVIEFEPRYAVRKPDGGWGEYVADLEVVPIGGEHIQAIDEPIIAKVGAHLGGVLGNVESHTRRTSEVSK
>NZ_AP022614.1|WP_085270825.1|4419592_4421167_+|acyl-CoA-carboxylase-subunit-beta
MTETAPAPIQHSTAEKLAELNARLELAKEPGGEKAAAKRDKKGIPSARARVHALVDPGTFLEIGALARTPNDPGALYGDGVVTGHAMIDGRPVGVFSHDQTVFQGSVGEMFGRKVARLMEWCAMVGCPIVGINDSAGARIQDTATSLAWYAELGRRHELLSGLVPQISIILGKCAGGAVYSPIQTDLVVAVRDQGYMFVTGPDVIKDVTGEDVTLDELGGADYQARYGNIHQVVESEAAAFQYVRDFLSFLPSNAFDKAPVVNPGLEPEITPSDLELDSIVPDSDNTAYDMHEILLRIFDDGDFLDVAAQAGQAIITGYARVDGRTVGVIANQPMHMSGAIDNEASDKAARFVRFCDAFDVPLVFVVDTPGFLPGVEQEKNGIIKRGGRFLYAVVEADVPKVTITVRKSYGGAYAVMGSRQLTADFNFAWPTARIAVIGADGAAQLLMKRFPDPTTPEAQQIKRDFIEGYNLNMAIPWIAAERGFIDAVIEPHQTRLLIRKSMHLLRDKQLWWRITRKHGLIPV

Crispr_ID: NZ_AP022614_7

• CRISPR_ID: NZ_AP022614_7
• CRISPR_location: 4611534-4612295
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 13 spacers
• Cas_protein_info: cas3

Consensus repeat of NZ_AP022614_7

Consensus_repeat	Method
GCCCCGCCGNCNCCGCCG	CRT

spacers of NZ_AP022614_7

>7.1|4611552|69|NZ_AP022614|CRT
GTCCCGCCGTCACCGAGCAGTGGCGCTGTGCCGCCGGTTCCCCCGGTCCCGCCGGTTGCGGTGGCGCTG
>7.2|4611639|39|NZ_AP022614|CRT
GAGCCACCGTCGGAGAACAGCAGCCCCGCCTGGCCGCCG
>7.3|4611696|69|NZ_AP022614|CRT
CCGACCTGGCCGAAGCCGCCGTCACCGCCCATGCCGCCGCTGCCGAACAGTATCCCGGCGTTGCCCCCG
>7.4|4611783|45|NZ_AP022614|CRT
GTGCCGGCCGCCCCGCTGGCACCGCCGAACCCGCCGTCGCCGCCC
>7.5|4611846|63|NZ_AP022614|CRT
AGCAGGCCCGCGCTGCCGCCGGCTCCGCCCGCGCCCCCGACGCCGGCGTCGCCGACGCCACCG
>7.6|4611927|51|NZ_AP022614|CRT
CCGGCGCCGAAGAACCCGCTGAGCAGGCCCCCGGCCCCGCCGGTCCCGCCT
>7.7|4611996|27|NZ_AP022614|CRT
GCGTCGTCGAACAGCGCGATCCCGCCG
>7.8|4612041|18|NZ_AP022614|CRT
CCGCCGATCAGCCCGCCG
>7.9|4612077|33|NZ_AP022614|CRT
GCACCCGCCGTGCTGGCGTCGCTGAATCCGCCG
>7.10|4612128|30|NZ_AP022614|CRT
TCGCCGGAGAACAAGCCGCCCATCCCACCG
>7.11|4612176|24|NZ_AP022614|CRT
CCGGCGGTCAACGAGCTCGCGCCG
>7.12|4612218|18|NZ_AP022614|CRT
ACTCCCAGCAGCCCCGCG
>7.13|4612254|24|NZ_AP022614|CRT
GCCTGGCCCGACCCGCCGGCACCT

CRISPR arrays and Neighbor proteins around NZ_AP022614_7

CRISPR arrays

The CRISPR arrays of NZ_AP022614_7

>merge|NZ_AP022614|7|4611534-4612295|CRT
ACCCCGGCGGCCCCGCCGGTCCCGCCGTCACCGAGCAGTGGCGCTGTGCCGCCGGTTCCCCCGGTCCCGCCGGTTGCGGTGGCGCTGAACCCGCCGGCGCCGCCGGAGCCACCGTCGGAGAACAGCAGCCCCGCCTGGCCGCCGTGCCCGCCGCCACCGCCGCCGACCTGGCCGAAGCCGCCGTCACCGCCCATGCCGCCGCTGCCGAACAGTATCCCGGCGTTGCCCCCGGCCCCGCCGGTTCCGCCGGTGCCGGCCGCCCCGCTGGCACCGCCGAACCCGCCGTCGCCGCCCGCCCCGCCGAAGCCGCCCAGCAGGCCCGCGCTGCCGCCGGCTCCGCCCGCGCCCCCGACGCCGGCGTCGCCGACGCCACCGGCACCGCCGTGCCCGCCGCCGGCGCCGAAGAACCCGCTGAGCAGGCCCCCGGCCCCGCCGGTCCCGCCTGCCCCGCCGGAGCCGCCGGCGTCGTCGAACAGCGCGATCCCGCCGGCACCCCCGACGCCGCCCCCGCCGATCAGCCCGCCGGCGCCGCCGACCCCGCCGGCACCCGCCGTGCTGGCGTCGCTGAATCCGCCGGCCCCGCCGACCCCGCCGTCGCCGGAGAACAAGCCGCCCATCCCACCGGCCCCACCGGCGCCGCCGCCGGCGGTCAACGAGCTCGCGCCGGCCCCGCCGGCGCCGCCGACTCCCAGCAGCCCCGCGGCCCCGCCGGCGCCGCCGGCCTGGCCCGACCCGCCGGCACCTGAGCCGCCGGCGCCGCCG

>NZ_AP022614|7|1|4611534-4612295|CRT
ACCCCGGCGGCCCCGCCG	GTCCCGCCGTCACCGAGCAGTGGCGCTGTGCCGCCGGTTCCCCCGGTCCCGCCGGTTGCGGTGGCGCTG
AACCCGCCGGCGCCGCCG	GAGCCACCGTCGGAGAACAGCAGCCCCGCCTGGCCGCCG
TGCCCGCCGCCACCGCCG	CCGACCTGGCCGAAGCCGCCGTCACCGCCCATGCCGCCGCTGCCGAACAGTATCCCGGCGTTGCCCCCG
GCCCCGCCGGTTCCGCCG	GTGCCGGCCGCCCCGCTGGCACCGCCGAACCCGCCGTCGCCGCCC
GCCCCGCCGAAGCCGCCC	AGCAGGCCCGCGCTGCCGCCGGCTCCGCCCGCGCCCCCGACGCCGGCGTCGCCGACGCCACCG
GCACCGCCGTGCCCGCCG	CCGGCGCCGAAGAACCCGCTGAGCAGGCCCCCGGCCCCGCCGGTCCCGCCT
GCCCCGCCGGAGCCGCCG	GCGTCGTCGAACAGCGCGATCCCGCCG
GCACCCCCGACGCCGCCC	CCGCCGATCAGCCCGCCG
GCGCCGCCGACCCCGCCG	GCACCCGCCGTGCTGGCGTCGCTGAATCCGCCG
GCCCCGCCGACCCCGCCG	TCGCCGGAGAACAAGCCGCCCATCCCACCG
GCCCCACCGGCGCCGCCG	CCGGCGGTCAACGAGCTCGCGCCG
GCCCCGCCGGCGCCGCCG	ACTCCCAGCAGCCCCGCG
GCCCCGCCGGCGCCGCCG	GCCTGGCCCGACCCGCCGGCACCT
GAGCCGCCGGCGCCGCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP022614.1|WP_007772268.1|4619393_4619597_+|cold-shock-protein-CspA	unknown	unknown	gnl|CDD|224197
NZ_AP022614.1|WP_085269158.1|4609178_4609379_+|DUF4244-domain-containing-protein	unknown	unknown	gnl|CDD|379429
NZ_AP022614.1|WP_085267343.1|4620512_4623347_+|type-I-DNA-topoisomerase	unknown	unknown	gnl|CDD|236048
NZ_AP022614.1|WP_085269159.1|4609435_4609705_+|pilus-biosynthesis-protein-TadE	unknown	unknown	unknown
NZ_AP022614.1|WP_085269145.1|4603034_4603793_+|oxidoreductase	unknown	unknown	unknown
NZ_AP022614.1|WP_085267347.1|4630806_4631175_-|DUF2304-domain-containing-protein	unknown	unknown	gnl|CDD|378376
NZ_AP022614.1|WP_163670897.1|4628061_4629891_-|hypothetical-protein	unknown	unknown	unknown
NZ_AP022614.1|WP_085267367.1|4625144_4626362_+|DNA-polymerase-III-subunit-delta'	unknown	unknown	gnl|CDD|236134
NZ_AP022614.1|WP_085267341.1|4616811_4619145_-|DEAD/DEAH-box-helicase	cas3	mkCas0139_cas3_CAS-I	gnl|CDD|274800
NZ_AP022614.1|WP_085267342.1|4619726_4620317_+|hypothetical-protein	unknown	unknown	unknown
NZ_AP022614.1|WP_085269150.1|4609592_4610033_+|flp-pilus-assembly-TadE/G-like-family-protein	unknown	unknown	gnl|CDD|274799
NZ_AP022614.1|WP_163670994.1|4614093_4616622_-|PE-domain-containing-protein	unknown	unknown	gnl|CDD|376422
NZ_AP022614.1|WP_085269149.1|4607745_4608549_+|type-II-secretion-system-F-family-protein	unknown	unknown	gnl|CDD|227300
NZ_AP022614.1|WP_085269151.1|4610033_4611065_-|DUF5593-domain-containg-protein	unknown	unknown	gnl|CDD|376047
NZ_AP022614.1|WP_139825590.1|4623360_4624935_-|HAMP-domain-containing-protein	unknown	unknown	gnl|CDD|143636
NZ_AP022614.1|WP_085269146.1|4604178_4605036_-|HAD-IB-family-hydrolase	unknown	unknown	gnl|CDD|273654
NZ_AP022614.1|WP_085267346.1|4629856_4630795_+|GDP-mannose-4,6-dehydratase	unknown	unknown	gnl|CDD|187566
NZ_AP022614.1|WP_085269148.1|4606573_4607749_+|TadA-family-conjugal-transfer-associated-ATPase	unknown	unknown	gnl|CDD|200328
NZ_AP022614.1|WP_085269157.1|4608560_4609142_+|type-II-secretion-system-F-family-protein	unknown	unknown	gnl|CDD|224975
NZ_AP022614.1|WP_085269144.1|4601418_4603023_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224048

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_AP022614.1|WP_085267341.1|4616811_4619145_-|DEAD/DEAH-box-helicase	cas3	mkCas0139_cas3_CAS-I	2.5e-17	56.9	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP022614.1|WP_007772268.1|4619393_4619597_+|cold-shock-protein-CspA	gnl|CDD|224197	COG1278, CspC, Cold shock proteins [Transcription].	2.2582e-35
NZ_AP022614.1|WP_085269158.1|4609178_4609379_+|DUF4244-domain-containing-protein	gnl|CDD|379429	pfam14029, DUF4244, Protein of unknown function (DUF4244). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 66 and 95 amino acids in length. There is a conserved EYA sequence motif.	2.10698e-16
NZ_AP022614.1|WP_085267343.1|4620512_4623347_+|type-I-DNA-topoisomerase	gnl|CDD|236048	PRK07561, PRK07561, DNA topoisomerase I subunit omega; Validated.	0
NZ_AP022614.1|WP_085267347.1|4630806_4631175_-|DUF2304-domain-containing-protein	gnl|CDD|378376	pfam10066, DUF2304, Uncharacterized conserved protein (DUF2304). Members of this family of hypothetical archaeal proteins have no known function.	1.31429e-26
NZ_AP022614.1|WP_085267367.1|4625144_4626362_+|DNA-polymerase-III-subunit-delta'	gnl|CDD|236134	PRK07940, PRK07940, DNA polymerase III subunit delta'; Validated.	0
NZ_AP022614.1|WP_085267341.1|4616811_4619145_-|DEAD/DEAH-box-helicase	gnl|CDD|274800	TIGR03817, DECH_helic, helicase/secretion neighborhood putative DEAH-box helicase. A conserved gene neighborhood widely spread in the Actinobacteria contains this uncharacterized DEAH-box family helicase encoded convergently towards an operon of genes for protein homologous to type II secretion and pilus formation proteins. The context suggests that this helicase may play a role in conjugal transfer of DNA.	0
NZ_AP022614.1|WP_085269157.1|4608560_4609142_+|type-II-secretion-system-F-family-protein	gnl|CDD|224975	COG2064, TadC, Flp pilus assembly protein TadC [Cell motility and secretion / Intracellular trafficking and secretion].	1.82876e-11
NZ_AP022614.1|WP_163670994.1|4614093_4616622_-|PE-domain-containing-protein	gnl|CDD|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	1.08201e-22
NZ_AP022614.1|WP_085269149.1|4607745_4608549_+|type-II-secretion-system-F-family-protein	gnl|CDD|227300	COG4965, TadB, Flp pilus assembly protein TadB [Intracellular trafficking and secretion].	7.00673e-40
NZ_AP022614.1|WP_085269151.1|4610033_4611065_-|DUF5593-domain-containg-protein	gnl|CDD|376047	pfam18621, DUF5628, Family of unknown function (DUF5628). This is a domain of unknown function found in Actinobacteria.	1.55014e-62
NZ_AP022614.1|WP_139825590.1|4623360_4624935_-|HAMP-domain-containing-protein	gnl|CDD|143636	cd07302, CHD, cyclase homology domain. Catalytic domains of the mononucleotidyl cyclases (MNC's), also called cyclase homology domains (CHDs), are part of the class III nucleotidyl cyclases. This class includes eukaryotic and prokaryotic adenylate cyclases (AC's) and guanylate cyclases (GC's). They seem to share a common catalytic mechanism in their requirement for two magnesium ions to bind the polyphosphate moiety of the nucleotide.	6.7643e-44
NZ_AP022614.1|WP_085269146.1|4604178_4605036_-|HAD-IB-family-hydrolase	gnl|CDD|273654	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490. This hypothetical equivalog is a member of the IB subfamily (TIGR01488) of the haloacid dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases. The sequences modelled here are all bacterial. The IB subfamily includes the enzyme phosphoserine phosphatase (TIGR00338). Due to this relationship, several of these sequences have been annotated as "phosphoserine phosphatase related proteins," or "Phosphoserine phosphatase-family enzymes." There is presently no evidence that any of the enzymes in this model possess PSPase activity. OMNI|NTL01ML1250 is annotated as a "possible transferase," however this is due to the C-terminal domain found on this sequence which is homologous to a group of glycerol-phosphate acyltransferases (between trusted and noise to TIGR00530). A subset of these sequences including OMNI|CC1962, the Caulobacter crescentus CicA protein cluster together and may represent a separate equivalog. [Unknown function, Enzymes of unknown specificity].	7.77633e-81
NZ_AP022614.1|WP_085267346.1|4629856_4630795_+|GDP-mannose-4,6-dehydratase	gnl|CDD|187566	cd05256, UDP_AE_SDR_e, UDP-N-acetylglucosamine 4-epimerase, extended (e) SDRs. This subgroup contains UDP-N-acetylglucosamine 4-epimerase of Pseudomonas aeruginosa, WbpP, an extended SDR, that catalyzes the NAD+ dependent conversion of UDP-GlcNAc and UDPGalNA to UDP-Glc and UDP-Gal. This subgroup has the characteristic active site tetrad and NAD-binding motif of the extended SDRs. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.19571e-123
NZ_AP022614.1|WP_085269148.1|4606573_4607749_+|TadA-family-conjugal-transfer-associated-ATPase	gnl|CDD|200328	TIGR03819, heli_sec_ATPase, helicase/secretion neighborhood ATPase. Members of this protein family comprise a distinct clade of putative ATPase associated with an integral membrane complex likely to act in pilus formation, secretion, or conjugal transfer. The association of most members with a nearby gene for a DEAH-box helicase suggests a role in conjugal transfer.	1.21651e-161
NZ_AP022614.1|WP_085269150.1|4609592_4610033_+|flp-pilus-assembly-TadE/G-like-family-protein	gnl|CDD|274799	TIGR03816, tadE_like_DECH, helicase/secretion neighborhood TadE-like protein. Members of this small, highly hydrophobic protein family occur in a pilus/secretion-like region that usually is next to an uncharacterized DEAH-box helicase, in Actinobacteria. Members show sequence similarity to the TadE-like family described by pfam07811. The function is unknown. [Unknown function, General].	8.0753e-17
NZ_AP022614.1|WP_085269144.1|4601418_4603023_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224048	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only].	0

Protein sequences

>NZ_AP022614.1|WP_085269151.1|4610033_4611065_-|DUF5593-domain-containg-protein
MAHDWLLVETLGGDPAVVAQGRQLKNLVPITSFLRRSPYLSAVRTAIAESLQTGQSLTSITPKRDRVIRTEPVVMSDGYIHGVHVWTGPADAEPPERPTPGPLKWDLTLGVATDTRESLTNSGKNPEVEVTLGRAFAEDLPSRELNPNETKVLAMAVKAKPDQTLCSTWDLTDWQGSPIRIGFVARTKIESGPDGRDHLVARAINWRCELKGPGVSTDDLAQRILSGLAQAGVHRALVDLNNWTLLKWLDEPCTFYDWKGTIETGKPKVHPDDERLMTSMTKEFADGATSRVLRMPGHDADWVPVHVTVNRIELEPETFAGLVSLRLPTTEELAGAGLPDSAT
>NZ_AP022614.1|WP_085269150.1|4609592_4610033_+|flp-pilus-assembly-TadE/G-like-family-protein
MCAATAISWSPRWSPTRSFCPPWPLGQRRYRPRSRCDDRGAATVLAAGMVIVLLWVTGAGAYLGSVVVARHRAQAAADLAALAAATRLPAGEAAACARATTVAREMGVDGDRCEVDGLDVVVTVRVGVPFAGVARAAARAGPVDTL
>NZ_AP022614.1|WP_085269159.1|4609435_4609705_+|pilus-biosynthesis-protein-TadE
MVLALCLAGLTAVSMQVRCVDAAREAARLAARGDQRSALEAAHRLAPGGARVDVRRDGDFLVATVVAHSKLLPTLAIGAKAVSAAEPLR
>NZ_AP022614.1|WP_085269158.1|4609178_4609379_+|DUF4244-domain-containing-protein
MINMFRAFLARLTVLVTDESGMSTVEYAIGTIAAAAFAAILYTVVTGDSIVSALTNIIARALNTKV
>NZ_AP022614.1|WP_085269157.1|4608560_4609142_+|type-II-secretion-system-F-family-protein
MLLALALWAGPGPAQVRSRAGAPPGGRRREPRDGPAHGPDPLAVASSLDVLAVCLGAGMAVPVAAAAAAESAPPALARILRRAGALLALGADPAVAWSVPAGLPGGAVDAQIDAVLRLARRSASSGAALADAVAELADQCRHDAAHAATAAAERAGVLIAGPLGLCFLPAFVCLGIAPVVAGLAGDVLQSGLL
>NZ_AP022614.1|WP_085269149.1|4607745_4608549_+|type-II-secretion-system-F-family-protein
MSGLSVAAALSAIALLVLPPSPRRRLAADSPVRRRIPAPGPGGVALAATCAVGLAALLLPLTTVLAAAAIGATTGLRYRRRLRARRATREGHTLGTALDVLVGELRVGSHPVRAFRVAAGETAGAVAESLGAVAARAGLGADVAAGLRAAARSSALPAQWGRLAVCWQLAGDHGLAIATLMRAAQRDIAARQRFSGSVSSSMAGARATATILAGLPVLGVLLGELIGARPLRFLLGGHAGGWLLVVGSTLACAGLLWSDRITDRIAS
>NZ_AP022614.1|WP_085269148.1|4606573_4607749_+|TadA-family-conjugal-transfer-associated-ATPase
MSGSLIERVRERLAADAAPPGSALRPSVVAAAIRAESGGMLGDTEVLANLRVLQTELTGAGILEPLLCADGTTDVLVTAPDAVWVDDGNGLRRSNIRFPDEAAVRRLAQRLALAAGRRLDDAQPWVDGQLTGIGAGAFAVRLHAVLPPVAAAGTCLSLRVLRPASQDLAALTAAGAVPPDAAVLVADIIAARLAFLVCGGTGAGKTTLLAAMLGAVAPTERIVCVEDAAELAPRHPHLVKLVARCANVEGAGEVPLRELVRQALRMRPDRIVVGEVRGAEVVDLLAALNTGHDGGAGTVHANSPGEVPARLEALGALGGLDRAALHSQLAAAVQVLLHVTRDRSGRRRLGEIAVLRETQGRVRAVTAWHADRGSTDDAAYLHRLLTSRLSA
>NZ_AP022614.1|WP_085269146.1|4604178_4605036_-|HAD-IB-family-hydrolase
MTVFDPAAQQHSSAESAANAAPSARTAAFFDLDKTIIAKSSTLAFSKPFFNQGLLNRRAVLKSSYAQFIYLLSGADHDQMDRMRAHMTNMCTGWDVEQVKSIVGETLHDIVTPLVFAEAADLIAAHKLCGRDVVVVSASGEEIVAPIARALGATHAMATRMVVEDGRYTGEIAFYCYGEGKVQAIRELAAREGYPLEHCYAYSDSITDLPMLESVGHPSVVNPDRSLRREAVERSWPVLTFSRPVSLRDRIPAPSGAAIATTAAVGISALAAGAVTYSLLRRFAF
>NZ_AP022614.1|WP_085269145.1|4603034_4603793_+|oxidoreductase
MTADPLAPLMELPGVAEASDRARDALGRAHRHRANLRGWPVTAAEASLRAARASSVLDGGPVRLDDLADGAGVSDPVFGGALRVAQALEGGEGPVVGIWRRAPLQALARLHMLAAADQVDADRLGRPRADAGVGPRLEMLAGLVTGGTRAPAPVVAAVAHGELLALRPFGSADGVVARAVSRLVTIASALDPHGLGVPEVSWMRQPSKYRDAVEGFAGGTPGGVGAWLVLCCRALQAGAQEALSIADSMPGR
>NZ_AP022614.1|WP_085269144.1|4601418_4603023_+|ABC-transporter-ATP-binding-protein
MSDPPPLLSVEGLQVAFGGRPAVRGAALTVAPAQTVAVVGESGSGKSTTAAAILGLLPPGGRITGGRIVFDGLDLTRADRRTLRSIRGRAIGYVPQDPMTNLNPVWKVGFQVREALRVNTGGRAARRRAVELLAEAGMPEAARQAGRYPHELSGGMCQRALIAIGLAGRPRLLIADEPTSALDVTVQRQVLDHLQRLTAESGTALLLITHDLALAAERAESVFVMHRGVVVESGAAAMILHNPRHEYTRRLVAAAPSLHVHGPARTRPDTADILVASELTKVYREPGGPPWRRKEFRAVDAVSFRLRRSSTLAVAGESGSGKSTLARMALGLLQPTSGTVLFDGSAVGKRSRRDELAFRRRVQPVFQNPYGSLDPRYSVFRAVEEPLRVHRVGNRRERERAVRELVDQVALPSSMLGRLPGELSGGQRQRVAIARALALRPDVLVCDEPVSALDVLVQAQILDLLADLQAELGLAYLFISHDLSVIRQIADDVLVMRAGRVVEEGPAAQVFGRPAQEYTRRLLEAIPRAPGRRG
>NZ_AP022614.1|WP_163670994.1|4614093_4616622_-|PE-domain-containing-protein
MAVPEGLGVASGDLASIGEAITAANAAAAARTTGMMAAAEDEVSTAIAALFSAHGSSFHALSAQAAAFHDQFVQTLSAGAGSYVDAETANVAAFAANPAQTMGQDLTTLINAPSLALTGRPLIGNGANGAAGTGQSGAAGGWLIGNGGAGGSGAAGQNGGNGGVAGLIGTGGVGGAGGAGGGAGGTGGAGGLLWGSGGSGGAGGYDLAGAGGAGGTGGTGGLFGAGGAGGAGGAAPNVGGGGAGGAGGTGGLLGGLFDAGGGDGGAGGISGTGAGGAGGAGGNAGLLAGSGGAGGTGGYSAAAIGGAGGAGGNAGLVFGPGGGGGTGGHSGTGTGGVGGAGGNAGLLLSSGGAGGGGGVAGLTGGAGGTGGAGGLFGVGGAGGAGGVSAGTGGAGGAGGSADLLVGVGGAGGAGGEGFTAGGAGGNAGATALIGTPGTAGEGGFGPAIGSAGLGGAGSPLQPAFDAINGPVEAATGRPLIGDGVSAAPGSGQNGTAGGWLLGDGGAGGSGTGMTGQGGGSGGAAGLLGAGGAGGAGGAGASSGGPGGAGGAGGAGGLISGVGGVGGDGGIAISAGTAGAGGAGGAGGLLGSGGGGGAGGVALSTDIGGAGGAGGAGGTGGVLGGLIGAGGGHGGLGGVSDDGIGGAGGAGGSAGPLAGPGGAGGDGAVGVVGGAGGSGGSAGVLVGGGGQGGIGGAGVTGDGGAGGTGGTAGALFSDGGAGGSGGFSIVAAGGAGGTGGNAFLVGDGGTGGAGGAGGAGTASGGAGGSGGNTFLLGDGGAGGEGGSSPAAAGAGGGGGGSAAIGDGGDGGNQGLGATTTDAAGVGGASGLLLGEQGINGSLA
>NZ_AP022614.1|WP_085267341.1|4616811_4619145_-|DEAD/DEAH-box-helicase
MATFGSDLLAVALAGTAADEHPLRHVAELPARGGRPAGWPAWAEPDVVRAFTDRGIAAPWSHQSAAADLAHAGRHVVLSTGTASGKSLAYQLPVLNALATDPRARVLYLSPTKALGHDQLRAATALTAAVPRLRDPGFGVAPTAYDGDSASEVRRFARERSRWLFSNPDMIHLSILRNHARWAALLRGLRFVVVDECHYYRGVFGSNVAMVLRRLLRLCARYSATPTFVFASATTDAPGATAAELIGRPVEEVTDDGSPQGSRTVALWEPALRTDLIGENGAPVRSSAGAEAARVMADLVAEGAQTLTFVRSRRAAELTALGAQARLDEIAPELSPRVASYRAGYLPEDRAALQRALAEGRLRGLATTNALELGVDIAGLDAVVLAGFPGTVASFWQQAGRSGRRGQGALVVLIARDDPLDTYLVHNPAALLGKPVERVVIDPANPYLLGPQLLCAACEMPLDAAEISAFGATEVARGLVEDGLLRVRNGRYFPAAGLQPHAAVDIRGSAGTQIVIVEADTGRLLGSVGADRAPASVHPGAVYLHQGESYVVDSLDLEDGIAFVHAEDPGYATFARELTDIAVTGAGERHEFGPVTLGLVPVRVTHRMVGYLRRRLNGEVIDFIELEMPERTLATTAVMYTITPEALLQKGIDAPRIPGSLHAAEHAAIGLLPLVASCDRGDIGGMSTAIGPDAAGLPSVFVYDGYPGGAGFAERGFRRARTWLGATADAIAACECPRGCPSCVQSPKCGNGNDPLDKAGAVLVLRLVLAELGAEAA
>NZ_AP022614.1|WP_007772268.1|4619393_4619597_+|cold-shock-protein-CspA
MPQGTVKWFNAEKGFGFIAPEDGSADVFVHYTEIQGSGFRTLEENQKVEFEIGHSPKGPQATGVRSL
>NZ_AP022614.1|WP_085267342.1|4619726_4620317_+|hypothetical-protein
MSQLSFFTAESVPPAVTDLSGVLAASGQIVLVGAPAPCGARLSVVVDRLWRASALAEMIREAGLAAEIGRTDEDTPLVRTDVNPALTGLAGEWTRGAVKTVPPRWLPGPRELRAWTLAAGHPEGEHYLLGLDPHAPDTHSPLASALMRVGIAPTLIGTRGGRPALRISGRRRLSRLVENVGEPPEGVDELSLWPRV
>NZ_AP022614.1|WP_085267343.1|4620512_4623347_+|type-I-DNA-topoisomerase
MADPKLKDRESGRNGSRRRLVIVESPTKARKLAGYLGSSYIVESSRGHIRDLPRAAADVPAKYKSEPWARLGVNVDADFEPLYIISPEKKHTVTELRDLLKGVDELYLATDGDREGEAIAWHLLETLKPNVPVKRMVFHEITEPAILEAAENPRDLDIDLVDAQETRRILDRLYGYEVSPVLWKKVAPRLSAGRVQSVATRIIVQRERDRMAFRSASYWDIVAQLDASVSDAKAQPPTFSARLTSVDGLRVASGRDFDSLGQLRKADEVTVLDEARATELAEGLRGAQLNVASVEEKPYTRRPYAPFMTSTLQQEAGRKLRFSSERTMSIAQRLYENGYITYMRTDSTTLSESAINAARTQARQLYGAEYVSPSPRQYTRKVKNAQEAHEAIRPAGDTFATPDAVRRELDGDEFRLYELIWQRTVASQMADARGTTLSLRINGRVQAAQTREVQFSASGRTITFAGFLKAYVETVDELVGGEADDAESRLPQLTQGQRLDVLELHPDGHATNPPARYTEASLVKALEELGIGRPSTYSSIIKTIQDRGYVHKKGSALVPSWVAFAVTGLLEQHFGRLVDYDFTAAMEDELDAIASGQERRTDWLNNFYFGGEHGVADSVARSGGLKKLVGVNLEGIDAREVNSIKLFDDEQGRPVYVRVGKNGPYLERMVTGDPDDPSGELKPQRANLNDSLTPDELTLEVAEELFATPQEGRSLGVDPETGHEIVAKDGRYGPYVTEILPEPPGGDDGSAGTPAKKGKKPTGPKPRTGSLLRSMDLQTVTLEDALKLLSLPRVVGVDPQTGEEITAQNGRYGPYLKRGTDSRSLATEDQIFGITLDEALKIYAEPKRRGRQSAAAPPLRELGTDPASGKPMVVKDGRFGPYVTDGETNASLRKGDDVASITDERAAELLADRRARGPAKRPAKKAARKAPAKKAPAKRAAKKT
>NZ_AP022614.1|WP_139825590.1|4623360_4624935_-|HAMP-domain-containing-protein
MRTPWPLFSLSMLQADIIGALFVLGFLRYALPPEDRIQLQDLPALNLAIFGLSLVVLVLAGWAVSLKLLMPVFRWQRRDILLADADPAATELARSRALRMPFYRTLTSMVAWAIGGVVFIIASWSVARFAAPVVAVATGLGAAATAIIGYLQSERVLRPVAVAALRSGVPENVQAPGVILRQMLTWMLSTAVPVLAIVLAVVADKASLLHATPEKLFTPILLLAVAALGIGFVSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRDLSERQRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTKLAATRPPAEVVHLLNEFFRVVVDTVGKHGGFVNKFQGDAALAIFGAPIEHPDSSGGALAAARELHDELLPVIGSAEFGIGVSSGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLESGHVLASAIAVSGALDAEALCWDVGEVVELRGRAAPTQLARPLKLAGVSNSAPSRARPSDMPSEAIGPGY
>NZ_AP022614.1|WP_085267367.1|4625144_4626362_+|DNA-polymerase-III-subunit-delta'
MSGVFTRLVGQEAVTAELLAAARAARGDVVHSGGGAGTMTHAWLITGPPGSGRSVAALCFAAALQCTSSVEDGGPGCGRCRACTTTLAGTHADVRRVIPEGLSIGVDEMRAIVQIASRRPSTGHRQIVVVEDADRLTEGAANALLKVVEEPPPSTVFLLCAPSVDPEDIAVTLRSRCRHVALVTPSTEAIAGVLVDSDGLPPDTATWAASVSGGHVGRARRLATDPEARERRERALALVRDAATPSRAYAAAEELVAAAEAEAVVLTADRAEAETEELRTALGAGGTGKGTAGAMRGAAGAMKDLERRQKSRHTRASRDALDRALIDLATYFRDALLLSAHAGGIRANHPDMTERIASLAAHATPERLLRCIEAVLDCREALAVNVKPKFAVDAMVATIGGELRD
>NZ_AP022614.1|WP_163670897.1|4628061_4629891_-|hypothetical-protein
MNPAAPVTSARTGPPYRVAVAAAALVVAQLAVRAALAFGGYFYWDDLILVGKAATHHLLSPSYLFDDHDGHLMPGAFLLAGVIIRLAPLDWTGPAISLLVLQLVASLALLRALHVILGWRPVLLIPLTFALFTPLAVPGFAWWAAALNSLPMLAALSWVCADAILLVRTGNQRYAVTGALAYLGGLLFFEKAAVIPFVAFAVAALLRHVQGDPTALRTVGRSGARLWVATLTTTVAWVAVYLAVVNQRRWSFDVAMTWNLLVRSFTRGIVPGLAGGPWHWDRWAPASPWATPPPAVAVLGWLVLAGLLAVSLVRKQRIGPVWLTALGYAVACQVPIYLMRSSRLTALELAQTLRYLPDLVVVLALLTAVALCAPNRPSAPRRLDASPRRAAVTVGLAASFLASSLYSTATFLTSWRDDPARAYLRNVRTALAAAHAESNAPLLDQEVDPLILQRVAAPEQLASHMFALLRDRPDFAMATTQLRMLDSSGRLVPARVTWIRTIAPGPMPRCGYFAQPDHPARLVLDGPLLPADWTAEINYLANSDGSMTMSLTQGPGVKVPVHPGLNRVFVRLPGAGDAITVRADTAALALCVASGPVGFVVPATGPPAR
>NZ_AP022614.1|WP_085267346.1|4629856_4630795_+|GDP-mannose-4,6-dehydratase
MRALVTGAAGFIGSTLVDRLLDDGHTVVGLDNFASGRATNLEHLAGNPAYGFVEADIVTADLEAILAEHRPEVVFHLAAQIDVRRSVAEPQFDASVNVMGTVRLAEAARRAGVRKVVHTSSGGSIYGTPPRYPTPETVPTDPASPYAAGKVAGEIYLNTFRHLYGIECSHIAPANVYGPRQDPHGEAGVVAIFAQALLSGKPTKVFGDGGKTRDYVFVDDVVDAFVKAAGEAGGGQRFNIGTGLETSDRQLHSAVAAAVGGPDEPEFHPDRLGDLRRSCLDIGLAQRVLGWQPKVQLDEGVRRTVEYFRSVR
>NZ_AP022614.1|WP_085267347.1|4630806_4631175_-|DUF2304-domain-containing-protein
MNWIQVLLIASIITLLVYLLRSRRNARSRAWVKVGYVVFVLGGIYAVLRPHDTTVVAHWFGIGRGTDLMLYALIMAFCFTTLSTYLRFKDLELRYARLARAVALEGAQPPEAEISSGTMKFE

Crispr_ID: NZ_AP022614_8

• CRISPR_ID: NZ_AP022614_8
• CRISPR_location: 4937496-4937578
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_AP022614_8

Consensus_repeat	Method
GATGGCGGCGACCCGCTTCGCCCGGCT	CRISPRCasFinder

spacers of NZ_AP022614_8

>8.1|4937523|29|NZ_AP022614|CRISPRCasFinder
GCGCCGCGCTCGCGATCGCCGCTGGTGCC

CRISPR arrays and Neighbor proteins around NZ_AP022614_8

CRISPR arrays

The CRISPR arrays of NZ_AP022614_8

>merge|NZ_AP022614|8|4937496-4937578|CRISPRCasFinder
GATGGCGGCGACCCGCTTCGCCCGGCTGCGCCGCGCTCGCGATCGCCGCTGGTGCCGATGGCGGCGACCCGCTTCGCCCGGCT

>NZ_AP022614|8|7|4937496-4937578|CRISPRCasFinder
GATGGCGGCGACCCGCTTCGCCCGGCT	GCGCCGCGCTCGCGATCGCCGCTGGTGCC
GATGGCGGCGACCCGCTTCGCCCGGCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP022614.1|WP_085268392.1|4943381_4943591_+|hypothetical-protein	unknown	unknown	gnl|CDD|319916
NZ_AP022614.1|WP_085268453.1|4926011_4926746_-|DUF429-domain-containing-protein	unknown	unknown	gnl|CDD|226778
NZ_AP022614.1|WP_085268395.1|4945638_4946502_-|DUF427-domain-containing-protein	unknown	unknown	gnl|CDD|377265
NZ_AP022614.1|WP_085268387.1|4938562_4939237_+|phosphoribosylformylglycinamidine-synthase-subunit-PurQ	unknown	unknown	gnl|CDD|235140
NZ_AP022614.1|WP_085268386.1|4938326_4938566_+|phosphoribosylformylglycinamidine-synthase-subunit-PurS	unknown	unknown	gnl|CDD|235659
NZ_AP022614.1|WP_085268378.1|4928254_4929514_+|cytochrome-P450	unknown	unknown	gnl|CDD|225035
NZ_AP022614.1|WP_085268391.1|4942698_4943169_-|hypothetical-protein	unknown	unknown	unknown
NZ_AP022614.1|WP_085268380.1|4930183_4931089_+|phosphoribosylaminoimidazolesuccinocarboxamide-synthase	unknown	unknown	gnl|CDD|237571
NZ_AP022614.1|WP_085268389.1|4940645_4941461_-|acyltransferase-family-protein	unknown	unknown	gnl|CDD|153249
NZ_AP022614.1|WP_085268388.1|4939233_4940604_-|wax-ester/triacylglycerol-synthase-family-O-acyltransferase	unknown	unknown	gnl|CDD|274360
NZ_AP022614.1|WP_085268390.1|4941611_4942691_+|NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|223528
NZ_AP022614.1|WP_085268382.1|4933272_4934862_-|DHA2-family-efflux-MFS-transporter-permease-subunit	unknown	unknown	gnl|CDD|129794
NZ_AP022614.1|WP_085268379.1|4929510_4930131_-|hypothetical-protein	unknown	unknown	unknown
NZ_AP022614.1|WP_085268383.1|4935062_4935767_+|DUF2334-domain-containing-protein	unknown	unknown	gnl|CDD|225773
NZ_AP022614.1|WP_085268393.1|4943653_4944109_-|cupin-domain-containing-protein	unknown	unknown	gnl|CDD|380340
NZ_AP022614.1|WP_085268381.1|4931085_4933218_+|S9-family-peptidase	unknown	unknown	gnl|CDD|224684
NZ_AP022614.1|WP_085268384.1|4935803_4937471_+|FAD-binding-dehydrogenase	unknown	unknown	gnl|CDD|183782
NZ_AP022614.1|WP_085268376.1|4925392_4926010_+|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225767
NZ_AP022614.1|WP_085268377.1|4926839_4928258_+|adenylosuccinate-lyase	unknown	unknown	gnl|CDD|176471
NZ_AP022614.1|WP_085268394.1|4944854_4945541_-|haloacid-dehalogenase-type-II	unknown	unknown	gnl|CDD|319787

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP022614.1|WP_085268392.1|4943381_4943591_+|hypothetical-protein	gnl|CDD|319916	cd07253, GLOD5, Human glyoxalase domain-containing protein 5 and similar proteins. Uncharacterized subfamily of VOC family contains human glyoxalase domain-containing protein 5 and similar proteins. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	4.24153e-11
NZ_AP022614.1|WP_085268453.1|4926011_4926746_-|DUF429-domain-containing-protein	gnl|CDD|226778	COG4328, COG4328, Predicted nuclease (RNAse H fold) [General function prediction only].	9.77812e-85
NZ_AP022614.1|WP_085268395.1|4945638_4946502_-|DUF427-domain-containing-protein	gnl|CDD|377265	pfam04248, NTP_transf_9, Domain of unknown function (DUF427). This domain contains a beta-tent fold.	3.13312e-24
NZ_AP022614.1|WP_085268383.1|4935062_4935767_+|DUF2334-domain-containing-protein	gnl|CDD|225773	COG3233, COG3233, Predicted deacetylase [General function prediction only].	3.13149e-80
NZ_AP022614.1|WP_085268386.1|4938326_4938566_+|phosphoribosylformylglycinamidine-synthase-subunit-PurS	gnl|CDD|235659	PRK05974, PRK05974, phosphoribosylformylglycinamidine synthase subunit PurS; Reviewed.	7.14928e-37
NZ_AP022614.1|WP_085268380.1|4930183_4931089_+|phosphoribosylaminoimidazolesuccinocarboxamide-synthase	gnl|CDD|237571	PRK13961, PRK13961, phosphoribosylaminoimidazole-succinocarboxamide synthase; Provisional.	0
NZ_AP022614.1|WP_085268389.1|4940645_4941461_-|acyltransferase-family-protein	gnl|CDD|153249	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this suubgroup are such LPLATs as 2-acylglycerol O-acyltransferase (MGAT), and similar proteins.	7.96599e-39
NZ_AP022614.1|WP_085268388.1|4939233_4940604_-|wax-ester/triacylglycerol-synthase-family-O-acyltransferase	gnl|CDD|274360	TIGR02946, Putative_diacyglycerol_O-acyltransferase_Mb3115, acyltransferase, WS/DGAT/MGAT. This bacteria-specific protein family includes a characterized, homodimeric, broad specificity acyltransferase from Acinetobacter sp. strain ADP1, active as wax ester synthase, as acyl coenzyme A:diacylglycerol acyltransferase, and as acyl-CoA:monoacylglycerol acyltransferase. [Unknown function, Enzymes of unknown specificity].	5.78731e-125
NZ_AP022614.1|WP_085268390.1|4941611_4942691_+|NAD(P)-dependent-oxidoreductase	gnl|CDD|223528	COG0451, WcaG, Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	1.16736e-30
NZ_AP022614.1|WP_085268382.1|4933272_4934862_-|DHA2-family-efflux-MFS-transporter-permease-subunit	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.14781e-153
NZ_AP022614.1|WP_085268378.1|4928254_4929514_+|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	5.86554e-93
NZ_AP022614.1|WP_085268387.1|4938562_4939237_+|phosphoribosylformylglycinamidine-synthase-subunit-PurQ	gnl|CDD|235140	PRK03619, PRK03619, phosphoribosylformylglycinamidine synthase subunit PurQ.	8.90765e-140
NZ_AP022614.1|WP_085268393.1|4943653_4944109_-|cupin-domain-containing-protein	gnl|CDD|380340	cd02210, cupin_BLR2406-like, Bradyrhizobium japonicum BLR2406 and related proteins, cupin domain. This family includes bacterial and fungal proteins homologous to BLR2406, a Bradyrhizobium japonicum protein of unknown function with a cupin beta barrel domain. Proteins in this subfamily appear to align closest to RmlC carbohydrate epimerase which is involved in dTDP-L-rhamnose production, and belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	2.91869e-34
NZ_AP022614.1|WP_085268381.1|4931085_4933218_+|S9-family-peptidase	gnl|CDD|224684	COG1770, PtrB, Protease II [Amino acid transport and metabolism].	0
NZ_AP022614.1|WP_085268384.1|4935803_4937471_+|FAD-binding-dehydrogenase	gnl|CDD|183782	PRK12834, PRK12834, putative FAD-binding dehydrogenase; Reviewed.	0
NZ_AP022614.1|WP_085268376.1|4925392_4926010_+|TetR-family-transcriptional-regulator	gnl|CDD|225767	COG3226, COG3226, Uncharacterized protein conserved in bacteria [Function unknown].	2.8922e-65
NZ_AP022614.1|WP_085268377.1|4926839_4928258_+|adenylosuccinate-lyase	gnl|CDD|176471	cd03302, Adenylsuccinate_lyase_2, Adenylsuccinate lyase (ASL)_subgroup 2. This subgroup contains mainly eukaryotic proteins similar to ASL, a member of the Lyase class I family. Members of this family for the most part catalyze similar beta-elimination reactions in which a C-N or C-O bond is cleaved with the release of fumarate as one of the products. These proteins are active as tetramers. The four active sites of the homotetrameric enzyme are each formed by residues from three different subunits. ASL catalyzes two steps in the de novo purine biosynthesis: the conversion of 5-aminoimidazole-(N-succinylocarboxamide) ribotide (SAICAR) into 5-aminoimidazole-4-carboxamide ribotide (AICAR) and, the conversion of adenylsuccinate (SAMP) into adenosine monophosphate (AMP). ASL deficiency has been linked to several pathologies including psychomotor retardation with autistic features, epilepsy and muscle wasting.	0
NZ_AP022614.1|WP_085268394.1|4944854_4945541_-|haloacid-dehalogenase-type-II	gnl|CDD|319787	cd02588, HAD_L2-DEX, L-2-haloacid dehalogenase. L-2-Haloacid dehalogenase catalyzes the hydrolytic dehalogenation of L-2-haloacids to produce the corresponding D-2-hydroxyacids with an inversion of the C2-configuration. 2-haloacid dehalogenases are of interest for their potential to degrade recalcitrant halogenated environmental pollutants and their use in the synthesis of industrial chemicals. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	4.4273e-76

Protein sequences

>NZ_AP022614.1|WP_085268384.1|4935803_4937471_+|FAD-binding-dehydrogenase
MSDSSATGFGADAIIVGAGLSGLVAACELVDRGLRVLILDQENSANLGGQAFWSFGGLFFVDSPEQRRLGIHDSHELALQDWLGTAAFDRPEDYWPSQWAHAYVDFAAGEKRSWLRARGLKIFPLVGWAERGGYDAQGHGNSVPRFHITWGTGPALVDIFARRLRDRSTVRFAHRHQVDELIVEGGAVTGVRGTVLEPCTAARGVPSSRNGIGQFEFRAPAIIVTSGGIGGNHDLVRKNWPKRMGRVPDQLLSGVPAHVDGRMIGISERAGARVINPDRMWHYTEGITNYDPVWPLHGIRIIPGPSSLWLDAEGKRLPVPLYPGFDTLGTLEYITKSGHDYTWFVLDSRIIEKEFALSGQEQNPDLTGQSVRELVRNRARSGPPGPVQAFVDRGVDFVSANSLRELVTAMNKLPDVTPLDYATVEAAVTARDREVANKYSKDGQVTAIRAARNYLGDRLGRVVAPHRLTDPKAGPLIAVKLHILTRKTLGGIETDLGARVLKADGTPLSGLYAAGEVAGFGGGGVHGYRALEGTFLGGCIFSGRAAGRGAADDIA
>NZ_AP022614.1|WP_085268383.1|4935062_4935767_+|DUF2334-domain-containing-protein
MSGNLIVSVSGIGDRTLADVEAFCAQMDARKVPVSLLVAPRLSGDYRLDRDPRTVEWLTGRRAGGDAIVLHGYDDAATKKRRGEFAILRAHEAGLRLKGADRVLEHLGLRTRLFAAPGWVVSPGVVKALPDNGFRLLADLHGITDLVRHNTVRSRVLGIGEGFLTEPWWCRMVVLSAERIARRGGVVRVAVAARHLRKPGPLQAMVDAVDLSLMHGCTPAVYSWRRDRAVLDAA
>NZ_AP022614.1|WP_085268382.1|4933272_4934862_-|DHA2-family-efflux-MFS-transporter-permease-subunit
MDKAPSAAAETALPAAPMPARDYPDGLDAALLRISGVCILATVMAILDVTVVSVAQRTFIEQFGSTQAVVAWTMTGYTLALTAVIPVTGWAADRFGTKRLFIWSVLAFTLGSLLCAVAPGILMLIVFRVVQGIGGGMLLPLGFIILTREAGPRRLGRLMSILSIPMLLAPIGGPILGGWLIDLTGWRWIFLINLPFGLITALLAWLVFERDAPAGSETFDLVGVLLLSPGLATFLFAVSSIPGRGTVADRHVLIPAAIGLTLIAAFVAHAWYRAHHPLIDLRLFGNRVLTQANLTMLVFAIAFFGAGLLLPSYFQQVLHYTPMQAGVHMIPQGLGAMVTMRLAGRIVDRQGPGKIVLVGIALITVGLGAFTFGVFRQVDYRPMLLVGLAVMGLGMGCTMMPLSVASVQSLTPPQIARGTTLISVSQQVGGSVGTALMSVILTNQFNRSQNIVAANKIAALKQRAAEGAVSVDGSAMPRESMAPGFAGNVIHDLSHAYTAVFAIAVVLVISTFIPAWFLPKQPPDLTVAE
>NZ_AP022614.1|WP_085268381.1|4931085_4933218_+|S9-family-peptidase
MTESALRVPVPPVAKRVETRREHHGDVFVDPYEWLRDKDNPDVIAYLEAENDYADRMTAGLEPLRQKIFDEIKARTKETDLSVPTRQGDWWYYARTFEGKQYRVQCRCPITGPDDWAPPALDEDTDIPGEQILLDSNAEAQGHEFFSLGAATVTLDGNLLAYSVDVIGDERYTLRFKDLRSGELYPDEIADIGAGATWAADNRTVYYQTLDTAHRPDKVWRYRLGSGEPSELVYHEPDERFWLGVGMTRSEAYIFIASGSAVTSEIRYADSADPHAQFTVVLPRREGVEYSVEHVVVGGRDRFLILHNDGAVNFTLTEAPVSDPTQQRTLIPHRDDVRLDAVDAFARHLVVSYRREALPRLQVWRIDDDGNYGEPEELSFDSELMSTGLAGNPNWDAPKLRIRAGSLVIPARVYDVDLATGQRILLREQPVLGGYSPADYVERRDWAVADDGARIPVSIVHRAGIELPAPALLYGYGAYEICTDPSFSIARLSLLDRGMVFAIAHVRGGGEMGRLWYERGKLLDKRNTFTDFIAVARHLVDSGVTQPRHLVALGGSAGGLLMGAVANLAPDLFAGILAQVPFVDPLTTILDPSLPLTVTEWDEWGNPLHDKDVYSYMKSYSPYENVESKRYPAILAMTSLHDTRVYYVEPAKWVAALRHANTDGNPILLKTQMNAGHGGVSGRYKAWQEAAFQYAWLLAAAEPDRYGRVQ
>NZ_AP022614.1|WP_085268380.1|4930183_4931089_+|phosphoribosylaminoimidazolesuccinocarboxamide-synthase
MRPALSDYRHLASGKVRELYRIDDEHLLLVASDRISAYDYVLDSTIPDKGRILTAMSFFFFGLVSDLVQAPNHLAGGPDDPRIPDEVLGRAMVARRLEMMPVECVARGYLTGSGLLDYQATGGVCGIPLPPGLVEASRFAEPLFTPATKAALGDHDENIPFARVVEMLGGVRANQLRDRTLKIYVHAADHALKRGIIIADTKFEFGTDRDGNLLLADEIFTPDSSRYWPAADYRAGVVQTSFDKQFVRNWLTSPESGWDRYGSQPPPPLPAPIIEATRDRYVEAYERISGLRFDDWIGPAA
>NZ_AP022614.1|WP_085268379.1|4929510_4930131_-|hypothetical-protein
MTSRFLPYSTRPGRLLAQLFSDFAVLVWTALWLLVGLAVYDAISTIAEAGRQVEDGARGIAGNLASAGHSAQHIPLVGDQVSTPLTSAADAALGLAGAGHNLDTTASWLAVLLAITVAALPILVAVGPWLFLRLRFFRRKLTVSALAATPAGEQLLALRALTNRPPGKLAEVGADPVGGWRREDPVTIRALAALELRSAGIRIRRR
>NZ_AP022614.1|WP_085268378.1|4928254_4929514_+|cytochrome-P450
MSPVGYRAEALAGVDFTDLDNFANGFPHELFALHRREAPVYWHEPTENTPDGEGFWSVATYPETLAVLRDPATYSSVTGGARPYGGTLLQDLAIAGQVLNMMDDPRHSQIRRLVSSGLTPRMIGLVEDDLRTRARRLLDDVVPGEPFDFLVDIAAELPMQMICILLGVPESERHWLFEAIEPQFDFGGSRKASLSQLSAEEAGSRMYAYGQRLIAAKRAEPTDDMLSVVANATLDDADAPSLSDLELYLFFSLLFSAGAETTRNAVAGGLLALAEHPEQLRALRADLGELPTAVEEMVRWTSPSPSKRRTATRDVTLGGHEIAAGQKIQVWEGSANRDAAVFDRADEFDIARKPNPHLGFGQGVHYCLGANLARLELRVLFEELLSRFGAVRVVRPVEWTRSNRHTGIRHLVVELLGGP
>NZ_AP022614.1|WP_085268377.1|4926839_4928258_+|adenylosuccinate-lyase
MSIPNVLANRYASAEMVAIWSPEAKIVAERRLWLAVLRAQAELGVAVPPDAVAAYERVLEDVDLGSIAARERTLRHDVKARIEEFNALAGHEQVHKGMTSRDLTENVEQLQVRRSLELVFSHGVAVAARLAERAVTYRDLVMAGRSHNVAAQATTLGKRFASAAQEVLVALARLRELIDRYPLRGIKGPMGTAQDMLDLMDGDADKLAELERRVAEFLGFTTVLTSVGQVYPRSLDHDVLSALVQLGAGPSSMAHTIRLMAGHELVTEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLRGYASMAAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRELDRYLPFLATTKVLMAAVRAGMGREAAHHVIREHAVATALAMRERGAEPDLLDRLAADERLPLDRAALHAALADKQAFTGAAGDQVDEVARAVGELVSRYPDAAKYTPGAIL
>NZ_AP022614.1|WP_085268453.1|4926011_4926746_-|DUF429-domain-containing-protein
MYFAGVDLAWAGRNPTGVAVVEPGGCLVSAGAVREDHEILAALGPYVQGDCVVGFDAPLVVTNPTGTRPAETALNRDFRRFEAGTHPANTGKPEFADGPRGGRLAASLGLDIDPRSPATRRALEVYPHAATVALFGLERTLKYKAKPGRTLERLRSELLLLMDGVERLACADVPLRVRDHPDWIGLRDQVTAAQRKSELRRAEDPIDAVVCAYVALYFWRKPAAVTIYGNLATGYIVTPSLPGS
>NZ_AP022614.1|WP_085268376.1|4925392_4926010_+|TetR-family-transcriptional-regulator
MTAAVTPKGERRRYALVSAAAELLAEGGFEAVRHRAVARRAGLPLASTTYYFSSLDDLIARAVEHIGMIEVAQLRARVTALSRRRRGPETTAEVLVDLLVGDVSGPGLTDHLISRYERHIACTRLPALRETMRRSLRQRAEAVAEAIERSGRSVRIELVCTLICAVDGSVVSALVEGGDPRTAALATVVDLIDVLAPIDQRPVRI
>NZ_AP022614.1|WP_085268386.1|4938326_4938566_+|phosphoribosylformylglycinamidine-synthase-subunit-PurS
MARVVVNVMPKGEILDPQGQAIVGALGRLGHPGIADVRQGKRFELEVDDSVDDAVLAEIAETLLANTVIEDWTITRETS
>NZ_AP022614.1|WP_085268387.1|4938562_4939237_+|phosphoribosylformylglycinamidine-synthase-subunit-PurQ
MTARIGIITFPGTLDDVDAARAARRVGAEAVNLWHADADLKGVDAVVVPGGFSYGDYLRCGAIAKFAPVMGEVVDAARRGMPVLGICNGFQVLCEAGLLPGALTRNVGLHFVCRDVWLRVASTSTAWTSRFEPDADLLVPLKSGEGRYVAPAEVLERLEGEGRVVFRYHENVNGSLHDIAGVSSENGRVVGLMPHPEHAIEALTGPSEDGLGLFYSALDAVLVA
>NZ_AP022614.1|WP_085268388.1|4939233_4940604_-|wax-ester/triacylglycerol-synthase-family-O-acyltransferase
MDAMLLYSETPNLHTHTLKVAVIDPSGADGDFGFDAFRRHVRRRLHLLEPLRYKLVDIPWQLHHPMWQEDCDVDLDYHLRRVEVPGPGGRRELDAVIGEVASTPLDRGRPLWEFHFAEGLSGGRCALIGKIHHALADGVASVNLLSRAMDLEDGPATSERDNDEAGITASPGDLLRAAARDHARQVAELPGLITNAAVGMARVRRRSKERGSNPDLAEAFDAPPTFLNHVVSPRRRFASATLPLPAAKATAKALGITMNDLILAIAAGGLRKLLLDYDGTADRPLIASVPTATDKSERITGNAISGLMISLPVHVADAAERARLVALATRIAKEDHEVMGPQLYGRMMAYLPTALAPAAFRWLGRRDIPNKLMNVAVSSVVGPRERGHFGGAPVTEIYSTGVLSPGAPVNITVWSYVGQLGVAVLTDDLTFKDPHDATDSLIASFAELRAAAGVSV
>NZ_AP022614.1|WP_085268389.1|4940645_4941461_-|acyltransferase-family-protein
MKDVTGTAADNQETRKWDPAFTQQVKNAVGPLVRRWYRAEVKNLSHIPPAGGALVVSNHSGGMLTPDVLIFASAFYEEFGYDRPIYTLAHYGVFIGPMDGWLRRMGVIEASRENAAAALHSGAVVLVFPGGDYDSYRPTLSANTIDFNGRTGYVRTAIEAGVPIVPTVSIGAQETQLFLTRGNWLARKLGLTKARMDILPVSFGFPFGLSVIFPPNLPLPAKIVTEVLEPIDVTARFGNDPDVDEVDAHVRSVMEAALKRLAAQRRFPVLG
>NZ_AP022614.1|WP_085268390.1|4941611_4942691_+|NAD(P)-dependent-oxidoreductase
MSETVLVTGGFGLVGSQTVPRLAADGHRVIATDLGTAAQRKAAGALPPGTEARWADLTDGGEVERLIAETTPTVIVHLAAMIPPLIYRRPALGRRVNVDATAALLRAARSSPHPVRFVQASSNAVYGARNPHRHHGLLRADSPMMPAELYGAHKAEAERAIRSSDLDWVILRLAGVISVEPGAMPFSADALFFESALPIDGRIHTVDVRDVALAFAAAATADVVGETLLIGGDSSHLLEQGDIGNALAAARGLIDALPGGRPGNPDSDDDWFVTDWMDTGRAQQALRFQRHTWPDMLEEMRAAAGWRRYPMRLASPLARQFLKRRAAYRHSPGPYADPWGAIRAGLGDPRPDVVGPAAI
>NZ_AP022614.1|WP_085268391.1|4942698_4943169_-|hypothetical-protein
MTGEPLCVDLIERYLRTRGRRYFRGHHDGEFFFVAEAQPRRLHVHLEISPSHDDVLIVRVAPGCFFPAVDRPWLAHFSERWSRLDRGVTAVVHDSSDPQRIGVVARTSQWIPADVPFEDFATFVDRTIAAATELFAALHQITELPSATGPLVRDAG
>NZ_AP022614.1|WP_085268392.1|4943381_4943591_+|hypothetical-protein
MGFEVERFDHIVLNCTGVDATASWYERDLGMQRETLGTSGRTALRFGNQKMTSHYCRDVDGNLIEIVAY
>NZ_AP022614.1|WP_085268393.1|4943653_4944109_-|cupin-domain-containing-protein
MATSDGFHPDLDDAPTEVTRDRVHHVKASQISSDTAQSEGLRRFAALSGRSVGAEKIWMGETHALPRSASDNHHHGESETAIYVRSGNPEFVFHDGVQEVRITAAPGDYVFIPPFLPHREENPDPDTTAEVVIARSSQEAIVVNLPELYPL
>NZ_AP022614.1|WP_085268394.1|4944854_4945541_-|haloacid-dehalogenase-type-II
MPKPSVLVFDVNETLIDLESIAPLFAELFGDERVLREWFAQLVMYSMTATLADCYVDFFSLGQGVLRMLGDIHGVPITDHDVHRVQAQMSAMPAYPDVVDGLTVLRDNGFRLATLTNSPHRPGATTPLENAGLAGFFEQQLSVDSCRAFKPSPAVYRHAYEALGVAPAECMMVAAHVWDILGAQNVGMRSALITRPGNPPLPVDGMPQPTLVVGDMRELAERLVDGGH
>NZ_AP022614.1|WP_085268395.1|4945638_4946502_-|DUF427-domain-containing-protein
MGLAWQQGPLATGSVGHFLTEQPLPSRLLFAEPLRRRMRVRFADVWIADSPDVVLLHEPGRYPVAYFPLSDVRGATLIAEERVTQHRDLGDTRWFTVAVPGRQAGHGAWRHTNLPRHAAVLDGRVAFAWRGMDAFYEEDERIVGHAADSYHRIDVRSTSRHLVVRDGERVIAETRQPLALYESGFAPRWYVPRADIDQAALKLVDGQTFCPYKGICSYYDVGGRRRAAWSYVGAWTEVGRVRNLVSFEPDKIDVHLDGQQLRLEPGQTVVPHGVDRGLDTDEVVGRH

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_AP022614_3	3.1|1901441|18|NZ_AP022614|CRISPRCasFinder	1901441-1901458	18	NZ_AP022614.1	1788608-1788625	0	1.0
NZ_AP022614_3	3.1|1901441|18|NZ_AP022614|CRISPRCasFinder	1901441-1901458	18	NZ_AP022614.1	4129091-4129108	0	1.0
NZ_AP022614_3	3.1|1901441|18|NZ_AP022614|CRISPRCasFinder	1901441-1901458	18	NZ_AP022614.1	108365-108382	1	0.944
NZ_AP022614_3	3.1|1901441|18|NZ_AP022614|CRISPRCasFinder	1901441-1901458	18	NZ_AP022614.1	1775726-1775743	1	0.944
NZ_AP022614_3	3.1|1901441|18|NZ_AP022614|CRISPRCasFinder	1901441-1901458	18	NZ_AP022614.1	1776240-1776257	1	0.944
NZ_AP022614_3	3.1|1901441|18|NZ_AP022614|CRISPRCasFinder	1901441-1901458	18	NZ_AP022614.1	1777386-1777403	1	0.944
NZ_AP022614_3	3.1|1901441|18|NZ_AP022614|CRISPRCasFinder	1901441-1901458	18	NZ_AP022614.1	1785152-1785169	1	0.944
NZ_AP022614_3	3.1|1901441|18|NZ_AP022614|CRISPRCasFinder	1901441-1901458	18	NZ_AP022614.1	1787942-1787959	1	0.944
NZ_AP022614_3	3.1|1901441|18|NZ_AP022614|CRISPRCasFinder	1901441-1901458	18	NZ_AP022614.1	1788125-1788142	1	0.944
NZ_AP022614_3	3.1|1901441|18|NZ_AP022614|CRISPRCasFinder	1901441-1901458	18	NZ_AP022614.1	1788455-1788472	1	0.944
NZ_AP022614_3	3.1|1901441|18|NZ_AP022614|CRISPRCasFinder	1901441-1901458	18	NZ_AP022614.1	2257895-2257912	1	0.944
NZ_AP022614_3	3.1|1901441|18|NZ_AP022614|CRISPRCasFinder	1901441-1901458	18	NZ_AP022614.1	4613292-4613309	1	0.944
NZ_AP022614_3	3.1|1901441|18|NZ_AP022614|CRISPRCasFinder	1901441-1901458	18	NZ_AP022614.1	4614365-4614382	1	0.944
NZ_AP022614_3	3.1|1901441|18|NZ_AP022614|CRISPRCasFinder	1901441-1901458	18	NZ_AP022614.1	4615439-4615456	1	0.944
NZ_AP022614_3	3.1|1901441|18|NZ_AP022614|CRISPRCasFinder	1901441-1901458	18	NZ_AP022614.1	4616102-4616119	1	0.944
NZ_AP022614_3	3.1|1901441|18|NZ_AP022614|CRISPRCasFinder	1901441-1901458	18	NZ_AP022614.1	4781009-4781026	1	0.944
NZ_AP022614_7	7.8|4612041|18|NZ_AP022614|CRT	4612041-4612058	18	NZ_AP022614.1	358543-358560	1	0.944
NZ_AP022614_7	7.8|4612041|18|NZ_AP022614|CRT	4612041-4612058	18	NZ_AP022614.1	1805500-1805517	1	0.944
NZ_AP022614_7	7.8|4612041|18|NZ_AP022614|CRT	4612041-4612058	18	NZ_AP022614.1	5502459-5502476	1	0.944
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_AP022614.1	2977243-2977271	2	0.931

1. spacer 3.1|1901441|18|NZ_AP022614|CRISPRCasFinder matches to position: 1788608-1788625, mismatch: 0, identity: 1.0

ccggcaccgccggtgccg	CRISPR spacer
ccggcaccgccggtgccg	Protospacer
******************

2. spacer 3.1|1901441|18|NZ_AP022614|CRISPRCasFinder matches to position: 4129091-4129108, mismatch: 0, identity: 1.0

ccggcaccgccggtgccg	CRISPR spacer
ccggcaccgccggtgccg	Protospacer
******************

3. spacer 3.1|1901441|18|NZ_AP022614|CRISPRCasFinder matches to position: 108365-108382, mismatch: 1, identity: 0.944

ccggcaccgccggtgccg	CRISPR spacer
ccggcgccgccggtgccg	Protospacer
*****.************

4. spacer 3.1|1901441|18|NZ_AP022614|CRISPRCasFinder matches to position: 1775726-1775743, mismatch: 1, identity: 0.944

ccggcaccgccggtgccg	CRISPR spacer
ccggcaccgccggcgccg	Protospacer
*************.****

5. spacer 3.1|1901441|18|NZ_AP022614|CRISPRCasFinder matches to position: 1776240-1776257, mismatch: 1, identity: 0.944

ccggcaccgccggtgccg	CRISPR spacer
ccggcaccgccggcgccg	Protospacer
*************.****

6. spacer 3.1|1901441|18|NZ_AP022614|CRISPRCasFinder matches to position: 1777386-1777403, mismatch: 1, identity: 0.944

ccggcaccgccggtgccg	CRISPR spacer
ccggtaccgccggtgccg	Protospacer
****.*************

7. spacer 3.1|1901441|18|NZ_AP022614|CRISPRCasFinder matches to position: 1785152-1785169, mismatch: 1, identity: 0.944

ccggcaccgccggtgccg	CRISPR spacer
ccggccccgccggtgccg	Protospacer
***** ************

8. spacer 3.1|1901441|18|NZ_AP022614|CRISPRCasFinder matches to position: 1787942-1787959, mismatch: 1, identity: 0.944

ccggcaccgccggtgccg	CRISPR spacer
ccggcaccgccgctgccg	Protospacer
************ *****

9. spacer 3.1|1901441|18|NZ_AP022614|CRISPRCasFinder matches to position: 1788125-1788142, mismatch: 1, identity: 0.944

ccggcaccgccggtgccg	CRISPR spacer
ccggccccgccggtgccg	Protospacer
***** ************

10. spacer 3.1|1901441|18|NZ_AP022614|CRISPRCasFinder matches to position: 1788455-1788472, mismatch: 1, identity: 0.944

ccggcaccgccggtgccg	CRISPR spacer
ccggcaccgccggcgccg	Protospacer
*************.****

11. spacer 3.1|1901441|18|NZ_AP022614|CRISPRCasFinder matches to position: 2257895-2257912, mismatch: 1, identity: 0.944

ccggcaccgccggtgccg	CRISPR spacer
ccgggaccgccggtgccg	Protospacer
**** *************

12. spacer 3.1|1901441|18|NZ_AP022614|CRISPRCasFinder matches to position: 4613292-4613309, mismatch: 1, identity: 0.944

ccggcaccgccggtgccg	CRISPR spacer
ccggcgccgccggtgccg	Protospacer
*****.************

13. spacer 3.1|1901441|18|NZ_AP022614|CRISPRCasFinder matches to position: 4614365-4614382, mismatch: 1, identity: 0.944

ccggcaccgccggtgccg	CRISPR spacer
ccggcaccgccggtcccg	Protospacer
************** ***

14. spacer 3.1|1901441|18|NZ_AP022614|CRISPRCasFinder matches to position: 4615439-4615456, mismatch: 1, identity: 0.944

ccggcaccgccggtgccg	CRISPR spacer
ccggctccgccggtgccg	Protospacer
***** ************

15. spacer 3.1|1901441|18|NZ_AP022614|CRISPRCasFinder matches to position: 4616102-4616119, mismatch: 1, identity: 0.944

ccggcaccgccggtgccg	CRISPR spacer
ccgacaccgccggtgccg	Protospacer
***.**************

16. spacer 3.1|1901441|18|NZ_AP022614|CRISPRCasFinder matches to position: 4781009-4781026, mismatch: 1, identity: 0.944

ccggcaccgccggtgccg	CRISPR spacer
ccggcaccgccgctgccg	Protospacer
************ *****

17. spacer 7.8|4612041|18|NZ_AP022614|CRT matches to position: 358543-358560, mismatch: 1, identity: 0.944

ccgccgatcagcccgccg	CRISPR spacer
ccgccgatcagtccgccg	Protospacer
***********.******

18. spacer 7.8|4612041|18|NZ_AP022614|CRT matches to position: 1805500-1805517, mismatch: 1, identity: 0.944

ccgccgatcagcccgccg	CRISPR spacer
ccgccggtcagcccgccg	Protospacer
******.***********

19. spacer 7.8|4612041|18|NZ_AP022614|CRT matches to position: 5502459-5502476, mismatch: 1, identity: 0.944

ccgccgatcagcccgccg	CRISPR spacer
ccgccgatcagtccgccg	Protospacer
***********.******

20. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to position: 2977243-2977271, mismatch: 2, identity: 0.931

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgcgctcgcgatcgccactagtgcc	Protospacer
********************.**.*****

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_AP022614_2	2.1|1900940|24|NZ_AP022614|CRISPRCasFinder	1900940-1900963	24	NZ_CP032676	Rhodococcus rhodochrous strain ATCC BAA870 plasmid pNit, complete sequence	260329-260352	1	0.958
NZ_AP022614_2	2.1|1900940|24|NZ_AP022614|CRISPRCasFinder	1900940-1900963	24	NC_004041	Rhizobium etli CFN 42 plasmid p42d, complete sequence	64312-64335	2	0.917
NZ_AP022614_2	2.1|1900940|24|NZ_AP022614|CRISPRCasFinder	1900940-1900963	24	NZ_CP021027	Rhizobium sp. TAL182 plasmid pRetTAL182c, complete sequence	82614-82637	2	0.917
NZ_AP022614_2	2.1|1900940|24|NZ_AP022614|CRISPRCasFinder	1900940-1900963	24	NZ_CP013555	Rhizobium phaseoli strain N931 plasmid pRphaN931c, complete sequence	123850-123873	2	0.917
NZ_AP022614_2	2.1|1900940|24|NZ_AP022614|CRISPRCasFinder	1900940-1900963	24	NZ_CP013587	Rhizobium phaseoli strain N161 plasmid pRphaN161b, complete sequence	66797-66820	2	0.917
NZ_AP022614_2	2.1|1900940|24|NZ_AP022614|CRISPRCasFinder	1900940-1900963	24	NZ_CP013598	Rhizobium sp. N741 plasmid pRspN741c, complete sequence	101237-101260	2	0.917
NZ_AP022614_2	2.1|1900940|24|NZ_AP022614|CRISPRCasFinder	1900940-1900963	24	NZ_CP013578	Rhizobium phaseoli strain N671 plasmid pRphaN671d, complete sequence	123459-123482	2	0.917
NZ_AP022614_2	2.1|1900940|24|NZ_AP022614|CRISPRCasFinder	1900940-1900963	24	NZ_CP013544	Rhizobium phaseoli strain R620 plasmid pRphaR620b, complete sequence	34088-34111	2	0.917
NZ_AP022614_2	2.1|1900940|24|NZ_AP022614|CRISPRCasFinder	1900940-1900963	24	NC_021909	Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1e, complete sequence	511117-511140	2	0.917
NZ_AP022614_2	2.1|1900940|24|NZ_AP022614|CRISPRCasFinder	1900940-1900963	24	NZ_CP013566	Rhizobium phaseoli strain N831 plasmid pRphaN831c, complete sequence	123850-123873	2	0.917
NZ_AP022614_2	2.1|1900940|24|NZ_AP022614|CRISPRCasFinder	1900940-1900963	24	NZ_CP013502	Rhizobium esperanzae strain N561 plasmid pRspN561b, complete sequence	101158-101181	2	0.917
NZ_AP022614_2	2.1|1900940|24|NZ_AP022614|CRISPRCasFinder	1900940-1900963	24	NZ_CP013508	Rhizobium sp. N1341 plasmid pRspN1341c, complete sequence	101237-101260	2	0.917
NZ_AP022614_2	2.1|1900940|24|NZ_AP022614|CRISPRCasFinder	1900940-1900963	24	NZ_CP013519	Rhizobium sp. N113 plasmid pRspN113b, complete sequence	101236-101259	2	0.917
NZ_AP022614_2	2.1|1900940|24|NZ_AP022614|CRISPRCasFinder	1900940-1900963	24	NZ_CP013572	Rhizobium phaseoli strain N771 plasmid pRphaN671d, complete sequence	123459-123482	2	0.917
NZ_AP022614_2	2.1|1900940|24|NZ_AP022614|CRISPRCasFinder	1900940-1900963	24	NZ_CP021125	Rhizobium sp. Kim5 plasmid pRetKim5a, complete sequence	93521-93544	2	0.917
NZ_AP022614_2	2.1|1900940|24|NZ_AP022614|CRISPRCasFinder	1900940-1900963	24	NZ_CP013492	Rhizobium sp. N6212 plasmid pRspN6212b, complete sequence	101234-101257	2	0.917
NZ_AP022614_2	2.1|1900940|24|NZ_AP022614|CRISPRCasFinder	1900940-1900963	24	NZ_CP013497	Rhizobium sp. N621 plasmid pRspN621b, complete sequence	101234-101257	2	0.917
NZ_AP022614_2	2.1|1900940|24|NZ_AP022614|CRISPRCasFinder	1900940-1900963	24	NZ_CP013592	Rhizobium sp. N871 plasmid pRspN871b, complete sequence	101158-101181	2	0.917
NZ_AP022614_2	2.1|1900940|24|NZ_AP022614|CRISPRCasFinder	1900940-1900963	24	NZ_CP017243	Rhizobium etli 8C-3 plasmid pRsp8C3b, complete sequence	81077-81100	2	0.917
NZ_AP022614_2	2.1|1900940|24|NZ_AP022614|CRISPRCasFinder	1900940-1900963	24	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	1699365-1699388	3	0.875
NZ_AP022614_2	2.1|1900940|24|NZ_AP022614|CRISPRCasFinder	1900940-1900963	24	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	3116510-3116533	3	0.875
NZ_AP022614_2	2.1|1900940|24|NZ_AP022614|CRISPRCasFinder	1900940-1900963	24	NZ_CP050096	Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b3, complete sequence	18547-18570	3	0.875
NZ_AP022614_2	2.1|1900940|24|NZ_AP022614|CRISPRCasFinder	1900940-1900963	24	NZ_CP050102	Rhizobium leguminosarum bv. trifolii strain 9B plasmid pRL9b2, complete sequence	18549-18572	3	0.875
NZ_AP022614_2	2.1|1900940|24|NZ_AP022614|CRISPRCasFinder	1900940-1900963	24	NZ_CP050107	Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b1, complete sequence	18548-18571	3	0.875
NZ_AP022614_2	2.1|1900940|24|NZ_AP022614|CRISPRCasFinder	1900940-1900963	24	NZ_CP050112	Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b5, complete sequence	18547-18570	3	0.875
NZ_AP022614_2	2.1|1900940|24|NZ_AP022614|CRISPRCasFinder	1900940-1900963	24	NZ_CP016452	Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence	1328817-1328840	3	0.875
NZ_AP022614_2	2.1|1900940|24|NZ_AP022614|CRISPRCasFinder	1900940-1900963	24	NZ_CP050089	Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b2, complete sequence	172905-172928	3	0.875
NZ_AP022614_2	2.1|1900940|24|NZ_AP022614|CRISPRCasFinder	1900940-1900963	24	NZ_CP053444	Rhizobium leguminosarum bv. trifolii strain CC275e plasmid pRltCC275eB, complete sequence	66074-66097	3	0.875
NZ_AP022614_2	2.1|1900940|24|NZ_AP022614|CRISPRCasFinder	1900940-1900963	24	NZ_CP026539	Desulfovibrio carbinolicus strain DSM 3852 plasmid pDCAR1, complete sequence	111139-111162	3	0.875
NZ_AP022614_7	7.13|4612254|24|NZ_AP022614|CRT	4612254-4612277	24	NZ_CP030864	Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence	328516-328539	3	0.875
NZ_AP022614_7	7.13|4612254|24|NZ_AP022614|CRT	4612254-4612277	24	NZ_CP054617	Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence	51541-51564	3	0.875
NZ_AP022614_7	7.13|4612254|24|NZ_AP022614|CRT	4612254-4612277	24	NZ_CP025547	Mycobacterium paragordonae strain 49061 plasmid unnamed1, complete sequence	260435-260458	3	0.875
NZ_AP022614_7	7.13|4612254|24|NZ_AP022614|CRT	4612254-4612277	24	NC_016652	Rhodococcus phage REQ2, complete genome	43245-43268	3	0.875
NZ_AP022614_2	2.1|1900940|24|NZ_AP022614|CRISPRCasFinder	1900940-1900963	24	NZ_CP007257	Rhodococcus erythropolis R138 plasmid pLRE138, complete sequence	237976-237999	4	0.833
NZ_AP022614_2	2.1|1900940|24|NZ_AP022614|CRISPRCasFinder	1900940-1900963	24	CP000662	Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA01, complete sequence	792238-792261	4	0.833
NZ_AP022614_2	2.1|1900940|24|NZ_AP022614|CRISPRCasFinder	1900940-1900963	24	NZ_CP029232	Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence	1213344-1213367	4	0.833
NZ_AP022614_2	2.1|1900940|24|NZ_AP022614|CRISPRCasFinder	1900940-1900963	24	NC_014030	Salinibacter ruber M8 plasmid pSR61, complete sequence	45498-45521	4	0.833
NZ_AP022614_7	7.7|4611996|27|NZ_AP022614|CRT	4611996-4612022	27	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	299948-299974	4	0.852
NZ_AP022614_7	7.7|4611996|27|NZ_AP022614|CRT	4611996-4612022	27	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	769847-769873	4	0.852
NZ_AP022614_7	7.7|4611996|27|NZ_AP022614|CRT	4611996-4612022	27	NZ_CP012915	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence	962363-962389	4	0.852
NZ_AP022614_7	7.7|4611996|27|NZ_AP022614|CRT	4611996-4612022	27	NZ_CP035419	Leisingera sp. NJS204 plasmid unnamed2, complete sequence	22928-22954	4	0.852
NZ_AP022614_7	7.7|4611996|27|NZ_AP022614|CRT	4611996-4612022	27	NZ_CP038236	Leisingera sp. NJS201 plasmid unnamed2, complete sequence	47889-47915	4	0.852
NZ_AP022614_7	7.7|4611996|27|NZ_AP022614|CRT	4611996-4612022	27	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	1786949-1786975	4	0.852
NZ_AP022614_7	7.7|4611996|27|NZ_AP022614|CRT	4611996-4612022	27	NZ_CP024895	Amycolatopsis sp. AA4 plasmid unnamed1, complete sequence	16012-16038	4	0.852
NZ_AP022614_7	7.7|4611996|27|NZ_AP022614|CRT	4611996-4612022	27	NZ_CP032340	Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence	1170016-1170042	4	0.852
NZ_AP022614_7	7.7|4611996|27|NZ_AP022614|CRT	4611996-4612022	27	NZ_CP038636	Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence	111547-111573	4	0.852
NZ_AP022614_7	7.7|4611996|27|NZ_AP022614|CRT	4611996-4612022	27	NZ_CP015441	Erythrobacter atlanticus strain s21-N3 plasmid unnamed, complete sequence	129104-129130	4	0.852
NZ_AP022614_7	7.10|4612128|30|NZ_AP022614|CRT	4612128-4612157	30	NC_009717	Xanthobacter autotrophicus Py2 plasmid pXAUT01, complete sequence	31456-31485	4	0.867
NZ_AP022614_7	7.13|4612254|24|NZ_AP022614|CRT	4612254-4612277	24	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	1100276-1100299	4	0.833
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	AB967974	Aurantimonas phage AmM-1 DNA, complete sequence	30062-30090	4	0.862
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_LN832562	Paracoccus aminovorans isolate JCM7685 plasmid IV, complete sequence	5057-5085	4	0.862
NZ_AP022614_5	5.1|3519949|28|NZ_AP022614|CRISPRCasFinder	3519949-3519976	28	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	571150-571177	5	0.821
NZ_AP022614_7	7.7|4611996|27|NZ_AP022614|CRT	4611996-4612022	27	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	23631-23657	5	0.815
NZ_AP022614_7	7.7|4611996|27|NZ_AP022614|CRT	4611996-4612022	27	NZ_CP023519	Burkholderia cepacia strain FDAARGOS_388 plasmid unnamed1, complete sequence	144956-144982	5	0.815
NZ_AP022614_7	7.7|4611996|27|NZ_AP022614|CRT	4611996-4612022	27	NZ_CP007745	Burkholderia cepacia ATCC 25416 plasmid unnamed, complete sequence	168871-168897	5	0.815
NZ_AP022614_7	7.7|4611996|27|NZ_AP022614|CRT	4611996-4612022	27	NZ_CP034813	Paracoccus sp. Arc7-R13 plasmid unnamed2, complete sequence	46828-46854	5	0.815
NZ_AP022614_7	7.7|4611996|27|NZ_AP022614|CRT	4611996-4612022	27	NZ_CP009572	Sphingomonas taxi strain ATCC 55669 plasmid STP1, complete sequence	56916-56942	5	0.815
NZ_AP022614_7	7.7|4611996|27|NZ_AP022614|CRT	4611996-4612022	27	NZ_CP022081	Burkholderia cepacia strain FDAARGOS_345 plasmid unnamed1, complete sequence	180228-180254	5	0.815
NZ_AP022614_7	7.7|4611996|27|NZ_AP022614|CRT	4611996-4612022	27	NZ_CP015322	Mesorhizobium amorphae CCNWGS0123 plasmid pM0123d, complete sequence	65933-65959	5	0.815
NZ_AP022614_7	7.7|4611996|27|NZ_AP022614|CRT	4611996-4612022	27	NZ_CP012984	Burkholderia cepacia ATCC 25416 strain UCB 717 plasmid pBC25416	127064-127090	5	0.815
NZ_AP022614_7	7.7|4611996|27|NZ_AP022614|CRT	4611996-4612022	27	NZ_CP034556	Burkholderia cepacia ATCC 25416 plasmid unnamed1, complete sequence	26074-26100	5	0.815
NZ_AP022614_7	7.7|4611996|27|NZ_AP022614|CRT	4611996-4612022	27	NZ_CP022568	Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK04, complete sequence	201839-201865	5	0.815
NZ_AP022614_7	7.7|4611996|27|NZ_AP022614|CRT	4611996-4612022	27	NZ_CP021368	Acidovorax carolinensis strain P4 plasmid pACP4.2, complete sequence	114740-114766	5	0.815
NZ_AP022614_7	7.7|4611996|27|NZ_AP022614|CRT	4611996-4612022	27	NZ_CP021364	Acidovorax carolinensis strain P3 plasmid pACP3.2, complete sequence	133814-133840	5	0.815
NZ_AP022614_7	7.7|4611996|27|NZ_AP022614|CRT	4611996-4612022	27	NZ_CP010859	Marinovum algicola DG 898 plasmid pMaD4, complete sequence	134045-134071	5	0.815
NZ_AP022614_7	7.7|4611996|27|NZ_AP022614|CRT	4611996-4612022	27	NZ_CP010865	Marinovum algicola DG 898 plasmid pMaD10, complete sequence	6782-6808	5	0.815
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP015322	Mesorhizobium amorphae CCNWGS0123 plasmid pM0123d, complete sequence	785215-785243	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP016613	Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence	1102316-1102344	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP021449	Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence	1131268-1131296	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	CP023013	Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence	1531355-1531383	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP049790	Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence	539201-539229	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP049794	Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence	112450-112478	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP049788	Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence	289380-289408	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP022766	Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence	1603965-1603993	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP021763	Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence	1609770-1609798	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP015116	Ralstonia solanacearum strain EP1 plasmid unnamed, complete sequence	1781952-1781980	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP016555	Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence	407059-407087	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP049792	Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence	1907810-1907838	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP052069	Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence	1528600-1528628	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP016915	Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence	1133997-1134025	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP016905	Ralstonia solanacearum strain KACC 10709 plasmid unnamed1	425458-425486	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP025986	Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence	2049296-2049324	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP022769	Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence	1611416-1611444	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP015851	Ralstonia solanacearum strain YC40-M plasmid, complete sequence	860632-860660	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP014942	Rhodococcus sp. BH4 plasmid, complete sequence	452556-452584	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP022773	Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence	1321064-1321092	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP022783	Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence	1537706-1537734	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP022791	Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence	1569322-1569350	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP022795	Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence	1534439-1534467	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP052071	Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence	768949-768977	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP022482	Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence	1505867-1505895	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP009763	Ralstonia solanacearum OE1-1 plasmid unnamed, complete sequence	1495773-1495801	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	CP023015	Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence	1533929-1533957	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP022779	Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence	1622896-1622924	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP052075	Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence	768949-768977	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP052085	Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence	1587209-1587237	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP052095	Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence	1621297-1621325	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP052105	Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence	768950-768978	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP021765	Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence	1609811-1609839	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP052077	Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence	1523507-1523535	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP052087	Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence	1587521-1587549	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP052097	Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence	1621297-1621325	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP052115	Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence	768952-768980	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP052127	Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence	1587209-1587237	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP052079	Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence	1524153-1524181	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP052089	Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence	1586412-1586440	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP052093	Ralstonia solanacearum strain FJAT15340.F50 plasmid Plas1, complete sequence	1621297-1621325	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP052101	Ralstonia solanacearum strain FJAT15304.F1 plasmid Plas1, complete sequence	1621297-1621325	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP052099	Ralstonia solanacearum strain FJAT15304.F50 plasmid Plas1, complete sequence	1621297-1621325	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP052107	Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence	768952-768980	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP022781	Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence	429870-429898	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP052117	Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence	768952-768980	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP052125	Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence	1523529-1523557	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP022793	Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence	1529006-1529034	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP022785	Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence	1509654-1509682	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP022787	Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence	1562603-1562631	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP022756	Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence	1601802-1601830	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP052129	Ralstonia solanacearum strain FJAT1303.F1 plasmid Plas1, complete sequence	1618612-1618640	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP052121	Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence	768952-768980	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP052123	Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence	1523529-1523557	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP052131	Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence	1587520-1587548	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	CP011998	Ralstonia solanacearum strain YC45 plasmid, complete sequence	1583397-1583425	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP052073	Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence	768946-768974	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP052081	Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence	1523529-1523557	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP052083	Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence	1523529-1523557	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP052109	Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence	768952-768980	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP052091	Ralstonia solanacearum strain FJAT15340.F6 plasmid Plas1, complete sequence	1621300-1621328	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP052111	Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence	423923-423951	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP052103	Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence	768952-768980	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP052119	Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence	768952-768980	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP052113	Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence	423923-423951	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NC_009427	Novosphingobium aromaticivorans DSM 12444 plasmid pNL2, complete sequence	421664-421692	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NC_007974	Cupriavidus metallidurans CH34 megaplasmid, complete sequence	1136966-1136994	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP046333	Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3	2502604-2502632	5	0.828
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	MK359313	Gordonia phage Vasanti, complete genome	7357-7385	5	0.828
NZ_AP022614_5	5.1|3519949|28|NZ_AP022614|CRISPRCasFinder	3519949-3519976	28	NZ_CP017076	Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence	390803-390830	6	0.786
NZ_AP022614_6	6.1|4403006|28|NZ_AP022614|CRISPRCasFinder	4403006-4403033	28	NZ_CP015203	Rhodococcus sp. 008 plasmid pR8L1, complete sequence	666455-666482	6	0.786
NZ_AP022614_7	7.7|4611996|27|NZ_AP022614|CRT	4611996-4612022	27	NZ_CP012915	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence	493430-493456	6	0.778
NZ_AP022614_7	7.7|4611996|27|NZ_AP022614|CRT	4611996-4612022	27	NZ_CP032340	Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence	1638939-1638965	6	0.778
NZ_AP022614_7	7.7|4611996|27|NZ_AP022614|CRT	4611996-4612022	27	NC_012811	Methylorubrum extorquens AM1 megaplasmid, complete sequence	918964-918990	6	0.778
NZ_AP022614_7	7.7|4611996|27|NZ_AP022614|CRT	4611996-4612022	27	NZ_CP013104	Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence	217623-217649	6	0.778
NZ_AP022614_7	7.7|4611996|27|NZ_AP022614|CRT	4611996-4612022	27	NZ_CP014942	Rhodococcus sp. BH4 plasmid, complete sequence	436063-436089	6	0.778
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NC_010604	Mycobacterium marinum M plasmid pMM23, complete sequence	8630-8658	6	0.793
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP015322	Mesorhizobium amorphae CCNWGS0123 plasmid pM0123d, complete sequence	198052-198080	6	0.793
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP034180	Mycobacteroides abscessus strain GZ002 plasmid pMabS_GZ002, complete sequence	7835-7863	6	0.793
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NC_010394	Mycobacterium abscessus plasmid, complete sequence	9582-9610	6	0.793
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NC_012528	Deinococcus deserti VCD115 plasmid 3, complete sequence	204002-204030	6	0.793
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	1274647-1274675	6	0.793
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP043499	Rhizobium grahamii strain BG7 plasmid unnamed, complete sequence	419409-419437	6	0.793
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP032323	Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence	823355-823383	6	0.793
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NC_022995	Burkholderia sp. M701 plasmid pM7012 DNA, complete sequence	123590-123618	6	0.793
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP015867	Streptomyces parvulus strain 2297 plasmid pSPA1, complete sequence	600083-600111	6	0.793
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_LR134467	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 25, complete sequence	51700-51728	6	0.793
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP023071	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence	1949004-1949032	6	0.793
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP045548	Streptomyces sp. SYP-A7193 plasmid unnamed1, complete sequence	306062-306090	6	0.793
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	JN811560	Pseudomonas phage JBD26, complete genome	9066-9094	6	0.793
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	KM389337	UNVERIFIED: Pseudomonas phage JBD58a clone contig00002 genomic sequence	6749-6777	6	0.793
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	MT114166	Microbacterium phage Nike, complete genome	10221-10249	6	0.793
NZ_AP022614_5	5.1|3519949|28|NZ_AP022614|CRISPRCasFinder	3519949-3519976	28	NZ_CP039696	Novosphingobium sp. ABRDHK2 plasmid pABRDHK21, complete sequence	29018-29045	7	0.75
NZ_AP022614_7	7.10|4612128|30|NZ_AP022614|CRT	4612128-4612157	30	MN961671	Pseudomonas aeruginosa strain 201330 plasmid p201330-IMP, complete sequence	153001-153030	7	0.767
NZ_AP022614_7	7.10|4612128|30|NZ_AP022614|CRT	4612128-4612157	30	NZ_CP039909	Agrobacterium tumefaciens strain CFBP6624 plasmid pAtCFBP6624, complete sequence	365828-365857	7	0.767
NZ_AP022614_7	7.10|4612128|30|NZ_AP022614|CRT	4612128-4612157	30	NZ_CP016452	Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence	2210399-2210428	7	0.767
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	MN586020	Microbacterium phage Megan, complete genome	18054-18082	7	0.759
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP021820	Sinorhizobium meliloti strain M162 plasmid psymB, complete sequence	1372899-1372927	7	0.759
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP021820	Sinorhizobium meliloti strain M162 plasmid psymB, complete sequence	1374394-1374422	7	0.759
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP021820	Sinorhizobium meliloti strain M162 plasmid psymB, complete sequence	1377184-1377212	7	0.759
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP021813	Sinorhizobium meliloti strain M270 plasmid psymA, complete sequence	398966-398994	7	0.759
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP021813	Sinorhizobium meliloti strain M270 plasmid psymA, complete sequence	400998-401026	7	0.759
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP021813	Sinorhizobium meliloti strain M270 plasmid psymA, complete sequence	689767-689795	7	0.759
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP021815	Sinorhizobium meliloti strain M270 plasmid accessoryA, complete sequence	132832-132860	7	0.759
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP021815	Sinorhizobium meliloti strain M270 plasmid accessoryA, complete sequence	134327-134355	7	0.759
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP021816	Sinorhizobium meliloti strain M270 plasmid accessoryB, complete sequence	107536-107564	7	0.759
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP021817	Sinorhizobium meliloti strain M270 plasmid accessoryC, complete sequence	97130-97158	7	0.759
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_AP014812	Methylorubrum populi strain P-1M plasmid pMPPM03, complete sequence	40172-40200	7	0.759
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP013345	Sphingopyxis macrogoltabida strain 203N plasmid unnamed1, complete sequence	260839-260867	7	0.759
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP012641	Massilia sp. WG5 plasmid unnamed 1, complete sequence	70985-71013	7	0.759
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP022363	Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence	179867-179895	7	0.759
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_AP022607	Mycobacterium branderi strain JCM 12687 plasmid pJCM12687	492102-492130	7	0.759
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_AP022607	Mycobacterium branderi strain JCM 12687 plasmid pJCM12687	509643-509671	7	0.759
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP015221	Rhodococcus sp. PBTS 2 plasmid unnamed1, complete sequence	96086-96114	7	0.759
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP020812	Mycobacterium dioxanotrophicus strain PH-06 plasmid unnamed3, complete sequence	104185-104213	7	0.759
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP020813	Mycobacterium dioxanotrophicus strain PH-06 plasmid unnamed4, complete sequence	4019-4047	7	0.759
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP034156	Rhodococcus sp. NJ-530 plasmid unnamed4, complete sequence	132018-132046	7	0.759
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	KR053201	Gordonia phage GTE8, complete genome	18442-18470	7	0.759
NZ_AP022614_7	7.9|4612077|33|NZ_AP022614|CRT	4612077-4612109	33	NZ_CP049794	Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence	132135-132167	8	0.758
NZ_AP022614_7	7.9|4612077|33|NZ_AP022614|CRT	4612077-4612109	33	NZ_CP049792	Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence	1927495-1927527	8	0.758
NZ_AP022614_7	7.9|4612077|33|NZ_AP022614|CRT	4612077-4612109	33	NZ_CP049790	Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence	519512-519544	8	0.758
NZ_AP022614_7	7.9|4612077|33|NZ_AP022614|CRT	4612077-4612109	33	NZ_CP016915	Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence	1114310-1114342	8	0.758
NZ_AP022614_7	7.10|4612128|30|NZ_AP022614|CRT	4612128-4612157	30	NZ_CP021798	Sinorhizobium meliloti strain USDA1106 plasmid psymA, complete sequence	145417-145446	8	0.733
NZ_AP022614_7	7.10|4612128|30|NZ_AP022614|CRT	4612128-4612157	30	CP054917	Streptomyces sp. NA02950 plasmid unnamed, complete sequence	98248-98277	8	0.733
NZ_AP022614_7	7.10|4612128|30|NZ_AP022614|CRT	4612128-4612157	30	NC_003037	Sinorhizobium meliloti 1021 plasmid pSymA, complete sequence	573147-573176	8	0.733
NZ_AP022614_7	7.10|4612128|30|NZ_AP022614|CRT	4612128-4612157	30	NZ_CP019483	Sinorhizobium meliloti strain B401 plasmid pSymA, complete sequence	505724-505753	8	0.733
NZ_AP022614_7	7.10|4612128|30|NZ_AP022614|CRT	4612128-4612157	30	NZ_CP019486	Sinorhizobium meliloti strain B399 plasmid pSymA, complete sequence	475265-475294	8	0.733
NZ_AP022614_7	7.10|4612128|30|NZ_AP022614|CRT	4612128-4612157	30	NC_020527	Sinorhizobium meliloti 2011 plasmid pSymA, complete sequence	572815-572844	8	0.733
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP039918	Agrobacterium tumefaciens strain CFBP6626 plasmid pAtCFBP6626a, complete sequence	109386-109414	8	0.724
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	LR606153	Rhizobium sp. Q54 genome assembly, plasmid: 10	7225-7253	8	0.724
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP013110	Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence	921100-921128	8	0.724
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP013054	Sinorhizobium americanum CCGM7 plasmid C, complete sequence	1471916-1471944	8	0.724
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	NZ_CP046575	Rhodococcus sp. WAY2 plasmid pRWAY03, complete sequence	200800-200828	8	0.724
NZ_AP022614_8	8.1|4937523|29|NZ_AP022614|CRISPRCasFinder	4937523-4937551	29	MN234172	Mycobacterium phage ThulaThula, complete genome	28531-28559	8	0.724
NZ_AP022614_3	3.3|1901552|33|NZ_AP022614|CRISPRCasFinder	1901552-1901584	33	NZ_CP031166	Euzebya sp. DY32-46 plasmid pEDY32-46I, complete sequence	49294-49326	9	0.727
NZ_AP022614_4	4.1|2419552|34|NZ_AP022614|CRISPRCasFinder	2419552-2419585	34	AF068845	Mycobacteriophage TM4, complete genome	21275-21308	9	0.735
NZ_AP022614_4	4.1|2419552|34|NZ_AP022614|CRISPRCasFinder	2419552-2419585	34	NC_003387	Mycobacterium phage TM4, complete genome	21275-21308	9	0.735
NZ_AP022614_4	4.1|2419552|34|NZ_AP022614|CRISPRCasFinder	2419552-2419585	34	KC787101	Mycobacterium phage 33D, partial genome	27121-27154	9	0.735
NZ_AP022614_7	7.9|4612077|33|NZ_AP022614|CRT	4612077-4612109	33	NZ_CP021914	Sagittula sp. P11 plasmid unnamed1, complete sequence	294032-294064	9	0.727
NZ_AP022614_4	4.1|2419552|34|NZ_AP022614|CRISPRCasFinder	2419552-2419585	34	NZ_CP035709	Sphaerotilus natans subsp. sulfidivorans strain D-507 plasmid pSna507_unt12, complete sequence	9930-9963	10	0.706
NZ_AP022614_3	3.2|1901486|39|NZ_AP022614|CRISPRCasFinder	1901486-1901524	39	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	350672-350710	11	0.718

1. spacer 2.1|1900940|24|NZ_AP022614|CRISPRCasFinder matches to NZ_CP032676 (Rhodococcus rhodochrous strain ATCC BAA870 plasmid pNit, complete sequence) position: , mismatch: 1, identity: 0.958

ccgttgccgccggggccgacgctg	CRISPR spacer
ccgttgccgccggggccaacgctg	Protospacer
*****************.******

2. spacer 2.1|1900940|24|NZ_AP022614|CRISPRCasFinder matches to NC_004041 (Rhizobium etli CFN 42 plasmid p42d, complete sequence) position: , mismatch: 2, identity: 0.917

ccgttgccgccggggccgacgctg	CRISPR spacer
cggttgccgccggggccgatgctg	Protospacer
* *****************.****

3. spacer 2.1|1900940|24|NZ_AP022614|CRISPRCasFinder matches to NZ_CP021027 (Rhizobium sp. TAL182 plasmid pRetTAL182c, complete sequence) position: , mismatch: 2, identity: 0.917

ccgttgccgccggggccgacgctg	CRISPR spacer
cggttgccgccggggccgatgctg	Protospacer
* *****************.****

4. spacer 2.1|1900940|24|NZ_AP022614|CRISPRCasFinder matches to NZ_CP013555 (Rhizobium phaseoli strain N931 plasmid pRphaN931c, complete sequence) position: , mismatch: 2, identity: 0.917

ccgttgccgccggggccgacgctg	CRISPR spacer
cggttgccgccggggccgatgctg	Protospacer
* *****************.****

5. spacer 2.1|1900940|24|NZ_AP022614|CRISPRCasFinder matches to NZ_CP013587 (Rhizobium phaseoli strain N161 plasmid pRphaN161b, complete sequence) position: , mismatch: 2, identity: 0.917

ccgttgccgccggggccgacgctg	CRISPR spacer
cggttgccgccggggccgatgctg	Protospacer
* *****************.****

6. spacer 2.1|1900940|24|NZ_AP022614|CRISPRCasFinder matches to NZ_CP013598 (Rhizobium sp. N741 plasmid pRspN741c, complete sequence) position: , mismatch: 2, identity: 0.917

ccgttgccgccggggccgacgctg	CRISPR spacer
cggttgccgccggggccgatgctg	Protospacer
* *****************.****

7. spacer 2.1|1900940|24|NZ_AP022614|CRISPRCasFinder matches to NZ_CP013578 (Rhizobium phaseoli strain N671 plasmid pRphaN671d, complete sequence) position: , mismatch: 2, identity: 0.917

ccgttgccgccggggccgacgctg	CRISPR spacer
cggttgccgccggggccgatgctg	Protospacer
* *****************.****

8. spacer 2.1|1900940|24|NZ_AP022614|CRISPRCasFinder matches to NZ_CP013544 (Rhizobium phaseoli strain R620 plasmid pRphaR620b, complete sequence) position: , mismatch: 2, identity: 0.917

ccgttgccgccggggccgacgctg	CRISPR spacer
cggttgccgccggggccgatgctg	Protospacer
* *****************.****

9. spacer 2.1|1900940|24|NZ_AP022614|CRISPRCasFinder matches to NC_021909 (Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1e, complete sequence) position: , mismatch: 2, identity: 0.917

ccgttgccgccggggccgacgctg	CRISPR spacer
ccgttgccgccggggccgatgttg	Protospacer
*******************.*.**

10. spacer 2.1|1900940|24|NZ_AP022614|CRISPRCasFinder matches to NZ_CP013566 (Rhizobium phaseoli strain N831 plasmid pRphaN831c, complete sequence) position: , mismatch: 2, identity: 0.917

ccgttgccgccggggccgacgctg	CRISPR spacer
cggttgccgccggggccgatgctg	Protospacer
* *****************.****

11. spacer 2.1|1900940|24|NZ_AP022614|CRISPRCasFinder matches to NZ_CP013502 (Rhizobium esperanzae strain N561 plasmid pRspN561b, complete sequence) position: , mismatch: 2, identity: 0.917

ccgttgccgccggggccgacgctg	CRISPR spacer
cggttgccgccggggccgatgctg	Protospacer
* *****************.****

12. spacer 2.1|1900940|24|NZ_AP022614|CRISPRCasFinder matches to NZ_CP013508 (Rhizobium sp. N1341 plasmid pRspN1341c, complete sequence) position: , mismatch: 2, identity: 0.917

ccgttgccgccggggccgacgctg	CRISPR spacer
cggttgccgccggggccgatgctg	Protospacer
* *****************.****

13. spacer 2.1|1900940|24|NZ_AP022614|CRISPRCasFinder matches to NZ_CP013519 (Rhizobium sp. N113 plasmid pRspN113b, complete sequence) position: , mismatch: 2, identity: 0.917

ccgttgccgccggggccgacgctg	CRISPR spacer
cggttgccgccggggccgatgctg	Protospacer
* *****************.****

14. spacer 2.1|1900940|24|NZ_AP022614|CRISPRCasFinder matches to NZ_CP013572 (Rhizobium phaseoli strain N771 plasmid pRphaN671d, complete sequence) position: , mismatch: 2, identity: 0.917

ccgttgccgccggggccgacgctg	CRISPR spacer
cggttgccgccggggccgatgctg	Protospacer
* *****************.****

15. spacer 2.1|1900940|24|NZ_AP022614|CRISPRCasFinder matches to NZ_CP021125 (Rhizobium sp. Kim5 plasmid pRetKim5a, complete sequence) position: , mismatch: 2, identity: 0.917

ccgttgccgccggggccgacgctg	CRISPR spacer
cggttgccgccggggccgatgctg	Protospacer
* *****************.****

16. spacer 2.1|1900940|24|NZ_AP022614|CRISPRCasFinder matches to NZ_CP013492 (Rhizobium sp. N6212 plasmid pRspN6212b, complete sequence) position: , mismatch: 2, identity: 0.917

ccgttgccgccggggccgacgctg	CRISPR spacer
cggttgccgccggggccgatgctg	Protospacer
* *****************.****

17. spacer 2.1|1900940|24|NZ_AP022614|CRISPRCasFinder matches to NZ_CP013497 (Rhizobium sp. N621 plasmid pRspN621b, complete sequence) position: , mismatch: 2, identity: 0.917

ccgttgccgccggggccgacgctg	CRISPR spacer
cggttgccgccggggccgatgctg	Protospacer
* *****************.****

18. spacer 2.1|1900940|24|NZ_AP022614|CRISPRCasFinder matches to NZ_CP013592 (Rhizobium sp. N871 plasmid pRspN871b, complete sequence) position: , mismatch: 2, identity: 0.917

ccgttgccgccggggccgacgctg	CRISPR spacer
cggttgccgccggggccgatgctg	Protospacer
* *****************.****

19. spacer 2.1|1900940|24|NZ_AP022614|CRISPRCasFinder matches to NZ_CP017243 (Rhizobium etli 8C-3 plasmid pRsp8C3b, complete sequence) position: , mismatch: 2, identity: 0.917

ccgttgccgccggggccgacgctg	CRISPR spacer
cggttgccgccggggccgatgctg	Protospacer
* *****************.****

20. spacer 2.1|1900940|24|NZ_AP022614|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 3, identity: 0.875

ccgttgccgccggggccgacgctg	CRISPR spacer
gagttgccgccggggccgatgctg	Protospacer
  *****************.****

21. spacer 2.1|1900940|24|NZ_AP022614|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 3, identity: 0.875

ccgttgccgccggggccgacgctg	CRISPR spacer
cgcttgccgcccgggccgacgctg	Protospacer
*  ******** ************

22. spacer 2.1|1900940|24|NZ_AP022614|CRISPRCasFinder matches to NZ_CP050096 (Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b3, complete sequence) position: , mismatch: 3, identity: 0.875

ccgttgccgccggggccgacgctg	CRISPR spacer
ccgttgccgccggtgccgaccctt	Protospacer
************* ****** ** 

23. spacer 2.1|1900940|24|NZ_AP022614|CRISPRCasFinder matches to NZ_CP050102 (Rhizobium leguminosarum bv. trifolii strain 9B plasmid pRL9b2, complete sequence) position: , mismatch: 3, identity: 0.875

ccgttgccgccggggccgacgctg	CRISPR spacer
ccgttgccgccggtgccgaccctt	Protospacer
************* ****** ** 

24. spacer 2.1|1900940|24|NZ_AP022614|CRISPRCasFinder matches to NZ_CP050107 (Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b1, complete sequence) position: , mismatch: 3, identity: 0.875

ccgttgccgccggggccgacgctg	CRISPR spacer
ccgttgccgccggtgccgaccctt	Protospacer
************* ****** ** 

25. spacer 2.1|1900940|24|NZ_AP022614|CRISPRCasFinder matches to NZ_CP050112 (Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b5, complete sequence) position: , mismatch: 3, identity: 0.875

ccgttgccgccggggccgacgctg	CRISPR spacer
ccgttgccgccggtgccgaccctt	Protospacer
************* ****** ** 

26. spacer 2.1|1900940|24|NZ_AP022614|CRISPRCasFinder matches to NZ_CP016452 (Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence) position: , mismatch: 3, identity: 0.875

ccgttgccgccggggccgacgctg	CRISPR spacer
ccgttgccgccggcgccgacgatc	Protospacer
************* ******* * 

27. spacer 2.1|1900940|24|NZ_AP022614|CRISPRCasFinder matches to NZ_CP050089 (Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b2, complete sequence) position: , mismatch: 3, identity: 0.875

ccgttgccgccggggccgacgctg	CRISPR spacer
ccgttgccgccggtgccgaccctt	Protospacer
************* ****** ** 

28. spacer 2.1|1900940|24|NZ_AP022614|CRISPRCasFinder matches to NZ_CP053444 (Rhizobium leguminosarum bv. trifolii strain CC275e plasmid pRltCC275eB, complete sequence) position: , mismatch: 3, identity: 0.875

ccgttgccgccggggccgacgctg	CRISPR spacer
ccgttgccgccggtgccgaccctt	Protospacer
************* ****** ** 

29. spacer 2.1|1900940|24|NZ_AP022614|CRISPRCasFinder matches to NZ_CP026539 (Desulfovibrio carbinolicus strain DSM 3852 plasmid pDCAR1, complete sequence) position: , mismatch: 3, identity: 0.875

ccgttgccgccggggccgacgctg	CRISPR spacer
cggttgccgccggggccgtcgctc	Protospacer
* **************** **** 

30. spacer 7.13|4612254|24|NZ_AP022614|CRT matches to NZ_CP030864 (Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence) position: , mismatch: 3, identity: 0.875

gcctggcccgacccgccggcacct	CRISPR spacer
gcctgtcccgtcccgccggcaccg	Protospacer
***** **** ************ 

31. spacer 7.13|4612254|24|NZ_AP022614|CRT matches to NZ_CP054617 (Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence) position: , mismatch: 3, identity: 0.875

gcctggcccgacccgccggcacct	CRISPR spacer
ccatggcccgacccgccggcccct	Protospacer
 * ***************** ***

32. spacer 7.13|4612254|24|NZ_AP022614|CRT matches to NZ_CP025547 (Mycobacterium paragordonae strain 49061 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.875

gcctggcccgacccgccggcacct	CRISPR spacer
gcctgacccgacccgccggccccg	Protospacer
*****.************** ** 

33. spacer 7.13|4612254|24|NZ_AP022614|CRT matches to NC_016652 (Rhodococcus phage REQ2, complete genome) position: , mismatch: 3, identity: 0.875

gcctggcccgacccgccggcacct	CRISPR spacer
gcccggcccggcccgccggcaccg	Protospacer
***.******.************ 

34. spacer 2.1|1900940|24|NZ_AP022614|CRISPRCasFinder matches to NZ_CP007257 (Rhodococcus erythropolis R138 plasmid pLRE138, complete sequence) position: , mismatch: 4, identity: 0.833

ccgttgccgccggggccgacgctg	CRISPR spacer
ccgttgccgccggggccgaggggc	Protospacer
******************* *   

35. spacer 2.1|1900940|24|NZ_AP022614|CRISPRCasFinder matches to CP000662 (Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA01, complete sequence) position: , mismatch: 4, identity: 0.833

ccgttgccgccggggccgacgctg	CRISPR spacer
agatcgccgccggggccgacgctg	Protospacer
  .*.*******************

36. spacer 2.1|1900940|24|NZ_AP022614|CRISPRCasFinder matches to NZ_CP029232 (Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence) position: , mismatch: 4, identity: 0.833

ccgttgccgccggggccgacgctg	CRISPR spacer
ccgttgccgtcggggccgacgtcc	Protospacer
*********.***********.. 

37. spacer 2.1|1900940|24|NZ_AP022614|CRISPRCasFinder matches to NC_014030 (Salinibacter ruber M8 plasmid pSR61, complete sequence) position: , mismatch: 4, identity: 0.833

ccgttgccgccggggccgacgctg	CRISPR spacer
ggggggccgccggggccgacgctg	Protospacer
  *  *******************

38. spacer 7.7|4611996|27|NZ_AP022614|CRT matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 4, identity: 0.852

gcgtcgtcgaacagcgcgatcccgccg	CRISPR spacer
tcctcgtcgaactgcgcgatcccgacg	Protospacer
 * ********* *********** **

39. spacer 7.7|4611996|27|NZ_AP022614|CRT matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 4, identity: 0.852

gcgtcgtcgaacagcgcgatcccgccg	CRISPR spacer
tcctcgtcgaactgcgcgatcccgacg	Protospacer
 * ********* *********** **

40. spacer 7.7|4611996|27|NZ_AP022614|CRT matches to NZ_CP012915 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence) position: , mismatch: 4, identity: 0.852

gcgtcgtcgaacagcgcgatcccgccg	CRISPR spacer
tcctcgtcgaactgcgcgatcccgacg	Protospacer
 * ********* *********** **

41. spacer 7.7|4611996|27|NZ_AP022614|CRT matches to NZ_CP035419 (Leisingera sp. NJS204 plasmid unnamed2, complete sequence) position: , mismatch: 4, identity: 0.852

gcgtcgtcgaacagcgcgatcccgccg	CRISPR spacer
tcatcgtcaaacagcgcgatcccgcag	Protospacer
 *.*****.**************** *

42. spacer 7.7|4611996|27|NZ_AP022614|CRT matches to NZ_CP038236 (Leisingera sp. NJS201 plasmid unnamed2, complete sequence) position: , mismatch: 4, identity: 0.852

gcgtcgtcgaacagcgcgatcccgccg	CRISPR spacer
tcatcgtcaaacagcgcgatcccgcag	Protospacer
 *.*****.**************** *

43. spacer 7.7|4611996|27|NZ_AP022614|CRT matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 4, identity: 0.852

gcgtcgtcgaacagcgcgatcccgccg	CRISPR spacer
tcctcgtcgaactgcgcgatcccgacg	Protospacer
 * ********* *********** **

44. spacer 7.7|4611996|27|NZ_AP022614|CRT matches to NZ_CP024895 (Amycolatopsis sp. AA4 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.852

gcgtcgtcgaacagcgcgatcccgccg	CRISPR spacer
acgtcgtcgaacagggcgaccccgcgg	Protospacer
.************* ****.***** *

45. spacer 7.7|4611996|27|NZ_AP022614|CRT matches to NZ_CP032340 (Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence) position: , mismatch: 4, identity: 0.852

gcgtcgtcgaacagcgcgatcccgccg	CRISPR spacer
tcctcgtcgaactgcgcgatcccgacg	Protospacer
 * ********* *********** **

46. spacer 7.7|4611996|27|NZ_AP022614|CRT matches to NZ_CP038636 (Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.852

gcgtcgtcgaacagcgcgatcccgccg	CRISPR spacer
gctctgtcgaacagcgcgataccgccg	Protospacer
** ..*************** ******

47. spacer 7.7|4611996|27|NZ_AP022614|CRT matches to NZ_CP015441 (Erythrobacter atlanticus strain s21-N3 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

gcgtcgtcgaacagcgcgatcccgccg	CRISPR spacer
gccacggcgaacagagcgatcccgccg	Protospacer
**  ** ******* ************

48. spacer 7.10|4612128|30|NZ_AP022614|CRT matches to NC_009717 (Xanthobacter autotrophicus Py2 plasmid pXAUT01, complete sequence) position: , mismatch: 4, identity: 0.867

tcgccggagaacaagccgcccatc-ccaccg	CRISPR spacer
acgacggagaacatgccgcccatctccacc-	Protospacer
 ** ********* ********** ***** 

49. spacer 7.13|4612254|24|NZ_AP022614|CRT matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 4, identity: 0.833

gcctggcccgacccgccggcacct	CRISPR spacer
gtctggcccgacccgccggcattc	Protospacer
*.*******************...

50. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to AB967974 (Aurantimonas phage AmM-1 DNA, complete sequence) position: , mismatch: 4, identity: 0.862

-gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
agcg-ggctctcgcgatcgccgctggcgcc	Protospacer
 ***  ** *****************.***

51. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_LN832562 (Paracoccus aminovorans isolate JCM7685 plasmid IV, complete sequence) position: , mismatch: 4, identity: 0.862

gcgccgcgctcgcgatcgccg-ctggtgcc	CRISPR spacer
acgccgcgcgcgcgatcgccgcctggcgc-	Protospacer
.******** *********** ****.** 

52. spacer 5.1|3519949|28|NZ_AP022614|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 5, identity: 0.821

gctgcgctctgcatcgtcgtaggcgcgc	CRISPR spacer
acggtgctctgcatcgtcgtcggcgtgc	Protospacer
.* *.*************** ****.**

53. spacer 7.7|4611996|27|NZ_AP022614|CRT matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 5, identity: 0.815

gcgtcgtcgaacagcgcgatcccgccg	CRISPR spacer
agcacgtcgaacagcgcgagcccgccg	Protospacer
.   *************** *******

54. spacer 7.7|4611996|27|NZ_AP022614|CRT matches to NZ_CP023519 (Burkholderia cepacia strain FDAARGOS_388 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.815

gcgtcgtcgaacagcgcgatcccgccg	CRISPR spacer
cggtcgtagaactgcgcgatcccgccc	Protospacer
  ***** **** ************* 

55. spacer 7.7|4611996|27|NZ_AP022614|CRT matches to NZ_CP007745 (Burkholderia cepacia ATCC 25416 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.815

gcgtcgtcgaacagcgcgatcccgccg	CRISPR spacer
cggtcgtagaactgcgcgatcccgccc	Protospacer
  ***** **** ************* 

56. spacer 7.7|4611996|27|NZ_AP022614|CRT matches to NZ_CP034813 (Paracoccus sp. Arc7-R13 plasmid unnamed2, complete sequence) position: , mismatch: 5, identity: 0.815

gcgtcgtcgaacagcgcgatcccgccg	CRISPR spacer
gtctcgtcgaacagcgcgatccccagg	Protospacer
*. ********************   *

57. spacer 7.7|4611996|27|NZ_AP022614|CRT matches to NZ_CP009572 (Sphingomonas taxi strain ATCC 55669 plasmid STP1, complete sequence) position: , mismatch: 5, identity: 0.815

gcgtcgtcgaacagcgcgatcccgccg	CRISPR spacer
aaatcgtcgaacagcgcgagccggccg	Protospacer
. .**************** ** ****

58. spacer 7.7|4611996|27|NZ_AP022614|CRT matches to NZ_CP022081 (Burkholderia cepacia strain FDAARGOS_345 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.815

gcgtcgtcgaacagcgcgatcccgccg	CRISPR spacer
cggtcgtagaactgcgcgatcccgccc	Protospacer
  ***** **** ************* 

59. spacer 7.7|4611996|27|NZ_AP022614|CRT matches to NZ_CP015322 (Mesorhizobium amorphae CCNWGS0123 plasmid pM0123d, complete sequence) position: , mismatch: 5, identity: 0.815

gcgtcgtcgaacagcgcgatcccgccg	CRISPR spacer
tcgtcgtcggacagcacgatcccgcgc	Protospacer
 ********.*****.*********  

60. spacer 7.7|4611996|27|NZ_AP022614|CRT matches to NZ_CP012984 (Burkholderia cepacia ATCC 25416 strain UCB 717 plasmid pBC25416) position: , mismatch: 5, identity: 0.815

gcgtcgtcgaacagcgcgatcccgccg	CRISPR spacer
cggtcgtagaactgcgcgatcccgccc	Protospacer
  ***** **** ************* 

61. spacer 7.7|4611996|27|NZ_AP022614|CRT matches to NZ_CP034556 (Burkholderia cepacia ATCC 25416 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.815

gcgtcgtcgaacagcgcgatcccgccg	CRISPR spacer
cggtcgtagaactgcgcgatcccgccc	Protospacer
  ***** **** ************* 

62. spacer 7.7|4611996|27|NZ_AP022614|CRT matches to NZ_CP022568 (Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK04, complete sequence) position: , mismatch: 5, identity: 0.815

gcgtcgtcgaacagcgcgatcc-cgccg	CRISPR spacer
tcgtcgtcgaacagcgccatccatggc-	Protospacer
 **************** **** .* * 

63. spacer 7.7|4611996|27|NZ_AP022614|CRT matches to NZ_CP021368 (Acidovorax carolinensis strain P4 plasmid pACP4.2, complete sequence) position: , mismatch: 5, identity: 0.815

gcgtcgtcgaacagcgcgatcccgccg	CRISPR spacer
gcgttgtcgaacagcgcgagccccagg	Protospacer
****.************** ***   *

64. spacer 7.7|4611996|27|NZ_AP022614|CRT matches to NZ_CP021364 (Acidovorax carolinensis strain P3 plasmid pACP3.2, complete sequence) position: , mismatch: 5, identity: 0.815

gcgtcgtcgaacagcgcgatcccgccg	CRISPR spacer
gcgttgtcgaacagcgcgagccccagg	Protospacer
****.************** ***   *

65. spacer 7.7|4611996|27|NZ_AP022614|CRT matches to NZ_CP010859 (Marinovum algicola DG 898 plasmid pMaD4, complete sequence) position: , mismatch: 5, identity: 0.815

gcgtcgtcgaacagcgcgatcccgccg	CRISPR spacer
tcgtcgtcgaagagcgcgatccgccgg	Protospacer
 ********** **********  * *

66. spacer 7.7|4611996|27|NZ_AP022614|CRT matches to NZ_CP010865 (Marinovum algicola DG 898 plasmid pMaD10, complete sequence) position: , mismatch: 5, identity: 0.815

gcgtcgtcgaacagcgcgatcccgccg	CRISPR spacer
gggtcgccgaacagctcgatcccgctc	Protospacer
* ****.******** *********. 

67. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP015322 (Mesorhizobium amorphae CCNWGS0123 plasmid pM0123d, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgcctcgctcgcgatcggcgctgggccg	Protospacer
***** ************ ******  * 

68. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP016613 (Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

69. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP021449 (Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

70. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to CP023013 (Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

71. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP049790 (Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

72. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP049794 (Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

73. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP049788 (Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

74. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP022766 (Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

75. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP021763 (Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

76. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP015116 (Ralstonia solanacearum strain EP1 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

77. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP016555 (Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

78. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP049792 (Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

79. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP052069 (Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

80. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP016915 (Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

81. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP016905 (Ralstonia solanacearum strain KACC 10709 plasmid unnamed1) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

82. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP025986 (Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

83. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP022769 (Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

84. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP015851 (Ralstonia solanacearum strain YC40-M plasmid, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

85. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP014942 (Rhodococcus sp. BH4 plasmid, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgagttcgcgatcgccgctgacacc	Protospacer
****** *.***************...**

86. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP022773 (Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

87. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP022783 (Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

88. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP022791 (Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

89. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP022795 (Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

90. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP052071 (Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

91. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP022482 (Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

92. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP009763 (Ralstonia solanacearum OE1-1 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

93. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to CP023015 (Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

94. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP022779 (Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

95. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP052075 (Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

96. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP052085 (Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

97. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP052095 (Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

98. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP052105 (Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

99. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP021765 (Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

100. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP052077 (Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

101. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP052087 (Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

102. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP052097 (Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

103. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP052115 (Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

104. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP052127 (Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

105. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP052079 (Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

106. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP052089 (Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

107. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP052093 (Ralstonia solanacearum strain FJAT15340.F50 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

108. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP052101 (Ralstonia solanacearum strain FJAT15304.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

109. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP052099 (Ralstonia solanacearum strain FJAT15304.F50 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

110. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP052107 (Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

111. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP022781 (Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

112. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP052117 (Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

113. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP052125 (Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

114. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP022793 (Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

115. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP022785 (Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

116. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP022787 (Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

117. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP022756 (Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

118. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP052129 (Ralstonia solanacearum strain FJAT1303.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

119. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP052121 (Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

120. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP052123 (Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

121. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP052131 (Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

122. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to CP011998 (Ralstonia solanacearum strain YC45 plasmid, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

123. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP052073 (Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

124. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP052081 (Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

125. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP052083 (Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

126. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP052109 (Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

127. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP052091 (Ralstonia solanacearum strain FJAT15340.F6 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

128. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP052111 (Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

129. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP052103 (Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

130. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP052119 (Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

131. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP052113 (Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgtgctcgcgctcgccgctgccgca	Protospacer
******.******* ********* .** 

132. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NC_009427 (Novosphingobium aromaticivorans DSM 12444 plasmid pNL2, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc----	CRISPR spacer
gcgccgcgctcgcggtcgcc----gtgccgcgc	Protospacer
**************.*****    *****    

133. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NC_007974 (Cupriavidus metallidurans CH34 megaplasmid, complete sequence) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgcgctcgcggccgccgctctttcc	Protospacer
**************..*******  * **

134. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP046333 (Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgcgctcgcggccgccgctctttcc	Protospacer
**************..*******  * **

135. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to MK359313 (Gordonia phage Vasanti, complete genome) position: , mismatch: 5, identity: 0.828

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gggtcgcgctcgcgatcgtcgcgggtgac	Protospacer
* *.**************.*** **** *

136. spacer 5.1|3519949|28|NZ_AP022614|CRISPRCasFinder matches to NZ_CP017076 (Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence) position: , mismatch: 6, identity: 0.786

gctgcgctctgcatcgtcgtaggcgcgc	CRISPR spacer
catgcgctcggcatcgtcgttggcgtgg	Protospacer
  ******* ********** ****.* 

137. spacer 6.1|4403006|28|NZ_AP022614|CRISPRCasFinder matches to NZ_CP015203 (Rhodococcus sp. 008 plasmid pR8L1, complete sequence) position: , mismatch: 6, identity: 0.786

cgcg-aagcaatgaggaggagcggcacca	CRISPR spacer
-gtgtcagcaatgaggaggagcagcacac	Protospacer
 *.*  ****************.****  

138. spacer 7.7|4611996|27|NZ_AP022614|CRT matches to NZ_CP012915 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence) position: , mismatch: 6, identity: 0.778

gcgtcgtcgaacagcgcgatcccgccg	CRISPR spacer
agcacgtcgaacagcgccagcccgccg	Protospacer
.   ************* * *******

139. spacer 7.7|4611996|27|NZ_AP022614|CRT matches to NZ_CP032340 (Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.778

gcgtcgtcgaacagcgcgatcccgccg	CRISPR spacer
agcacgtcgaacagcgccagcccgccg	Protospacer
.   ************* * *******

140. spacer 7.7|4611996|27|NZ_AP022614|CRT matches to NC_012811 (Methylorubrum extorquens AM1 megaplasmid, complete sequence) position: , mismatch: 6, identity: 0.778

gcgtcgtcgaacagcgcgatcccgccg	CRISPR spacer
ccgtcgacgaacagcgcgttcccgggc	Protospacer
 ***** *********** *****   

141. spacer 7.7|4611996|27|NZ_AP022614|CRT matches to NZ_CP013104 (Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence) position: , mismatch: 6, identity: 0.778

gcgtcgtcgaacagcgcgatcccgccg	CRISPR spacer
aacgcgccgaacagcgcgatcacgccg	Protospacer
.   **.************** *****

142. spacer 7.7|4611996|27|NZ_AP022614|CRT matches to NZ_CP014942 (Rhodococcus sp. BH4 plasmid, complete sequence) position: , mismatch: 6, identity: 0.778

gcgtcgtcgaacagcgcgatcccgccg	CRISPR spacer
atctcgtcgaactgcacgatcccgcct	Protospacer
.. ********* **.********** 

143. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NC_010604 (Mycobacterium marinum M plasmid pMM23, complete sequence) position: , mismatch: 6, identity: 0.793

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
cgaccgcgctagtgatcgccgctggtgca	Protospacer
  .******* *.*************** 

144. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP015322 (Mesorhizobium amorphae CCNWGS0123 plasmid pM0123d, complete sequence) position: , mismatch: 6, identity: 0.793

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
acgccgcgctcgcgatcgccggtgaggtg	Protospacer
.******************** **. *. 

145. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP034180 (Mycobacteroides abscessus strain GZ002 plasmid pMabS_GZ002, complete sequence) position: , mismatch: 6, identity: 0.793

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
cgaccgcgctagtgatcgccgctggtgca	Protospacer
  .******* *.*************** 

146. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NC_010394 (Mycobacterium abscessus plasmid, complete sequence) position: , mismatch: 6, identity: 0.793

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
cgaccgcgctagtgatcgccgctggtgca	Protospacer
  .******* *.*************** 

147. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NC_012528 (Deinococcus deserti VCD115 plasmid 3, complete sequence) position: , mismatch: 6, identity: 0.793

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcggcgcgctcgccatcgccgctgtcgtg	Protospacer
*** ********* ********** .*. 

148. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 6, identity: 0.793

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
tcgccggggtcgcgatcgccgctggcgat	Protospacer
 ***** * ****************.* .

149. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP043499 (Rhizobium grahamii strain BG7 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
cagccgcgatcgcgatcgccgcgggtatc	Protospacer
  ****** ************* ***..*

150. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP032323 (Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence) position: , mismatch: 6, identity: 0.793

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgcggtcgcgatcgccgataggacg	Protospacer
******** ************ *.* .* 

151. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NC_022995 (Burkholderia sp. M701 plasmid pM7012 DNA, complete sequence) position: , mismatch: 6, identity: 0.793

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gccccgcgctcgccatcgccgctacatcc	Protospacer
** ********** *********.   **

152. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP015867 (Streptomyces parvulus strain 2297 plasmid pSPA1, complete sequence) position: , mismatch: 6, identity: 0.793

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
tcgccgccctcccgatcgccgctgagtcc	Protospacer
 ****** *** ************.  **

153. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_LR134467 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 25, complete sequence) position: , mismatch: 6, identity: 0.793

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
tcgccgccctcgcgatcgccgcctggggc	Protospacer
 ****** **************. * * *

154. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP023071 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence) position: , mismatch: 6, identity: 0.793

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gtacgccgctcgtgatcgccgccggtgcc	Protospacer
*..*  ******.*********.******

155. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP045548 (Streptomyces sp. SYP-A7193 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.793

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcggcgggctcgcgatcgccgctcatcgc	Protospacer
*** ** **************** .*  *

156. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to JN811560 (Pseudomonas phage JBD26, complete genome) position: , mismatch: 6, identity: 0.793

gcgccgcgctcgcgatcgccgctggtgcc-----	CRISPR spacer
gcgccgcgctcgcggtcgccg-----gcctccag	Protospacer
**************.******     ***     

157. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to KM389337 (UNVERIFIED: Pseudomonas phage JBD58a clone contig00002 genomic sequence) position: , mismatch: 6, identity: 0.793

gcgccgcgctcgcgatcgccgctggtgcc-----	CRISPR spacer
gcgccgcgctcgcggtcgccg-----gcctccag	Protospacer
**************.******     ***     

158. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to MT114166 (Microbacterium phage Nike, complete genome) position: , mismatch: 6, identity: 0.793

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
ccgccgcgttcgcgatcgccgccgacacc	Protospacer
 *******.*************.*...**

159. spacer 5.1|3519949|28|NZ_AP022614|CRISPRCasFinder matches to NZ_CP039696 (Novosphingobium sp. ABRDHK2 plasmid pABRDHK21, complete sequence) position: , mismatch: 7, identity: 0.75

gctgcgctctgcatcgtcgtaggcgcgc	CRISPR spacer
gtggcgctctgcatcgtcgcaggcatcg	Protospacer
*. ****************.****..  

160. spacer 7.10|4612128|30|NZ_AP022614|CRT matches to MN961671 (Pseudomonas aeruginosa strain 201330 plasmid p201330-IMP, complete sequence) position: , mismatch: 7, identity: 0.767

--tcgccggagaacaagccgcccatcccaccg	CRISPR spacer
gttcatcaggaa--aagccgcccatcccaccg	Protospacer
  **..*.*..*  ******************

161. spacer 7.10|4612128|30|NZ_AP022614|CRT matches to NZ_CP039909 (Agrobacterium tumefaciens strain CFBP6624 plasmid pAtCFBP6624, complete sequence) position: , mismatch: 7, identity: 0.767

tcgccggagaacaagccgcccatcccaccg	CRISPR spacer
acgacggagaacatgccgcccatctcgatg	Protospacer
 ** ********* **********.*. .*

162. spacer 7.10|4612128|30|NZ_AP022614|CRT matches to NZ_CP016452 (Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence) position: , mismatch: 7, identity: 0.767

tcgccggagaacaagccgcccatcccaccg	CRISPR spacer
acgacggagaacatgccgcccatctcgatg	Protospacer
 ** ********* **********.*. .*

163. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to MN586020 (Microbacterium phage Megan, complete genome) position: , mismatch: 7, identity: 0.759

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
ccgccgcgctcgcgctcgccgctgagaag	Protospacer
 ************* *********. .  

164. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP021820 (Sinorhizobium meliloti strain M162 plasmid psymB, complete sequence) position: , mismatch: 7, identity: 0.759

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
acgccacgctcgcgatcgccgcttacgga	Protospacer
.****.***************** ..*  

165. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP021820 (Sinorhizobium meliloti strain M162 plasmid psymB, complete sequence) position: , mismatch: 7, identity: 0.759

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
acgccacgctcgcgatcgccgcttacgga	Protospacer
.****.***************** ..*  

166. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP021820 (Sinorhizobium meliloti strain M162 plasmid psymB, complete sequence) position: , mismatch: 7, identity: 0.759

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
acgccacgctcgcgatcgccgcttacgga	Protospacer
.****.***************** ..*  

167. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP021813 (Sinorhizobium meliloti strain M270 plasmid psymA, complete sequence) position: , mismatch: 7, identity: 0.759

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
acgccacgctcgcgatcgccgcttacgga	Protospacer
.****.***************** ..*  

168. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP021813 (Sinorhizobium meliloti strain M270 plasmid psymA, complete sequence) position: , mismatch: 7, identity: 0.759

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
acgccacgctcgcgatcgccgcttacgga	Protospacer
.****.***************** ..*  

169. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP021813 (Sinorhizobium meliloti strain M270 plasmid psymA, complete sequence) position: , mismatch: 7, identity: 0.759

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
acgccacgctcgcgatcgccgcttacgga	Protospacer
.****.***************** ..*  

170. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP021815 (Sinorhizobium meliloti strain M270 plasmid accessoryA, complete sequence) position: , mismatch: 7, identity: 0.759

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
acgccacgctcgcgatcgccgcttacgga	Protospacer
.****.***************** ..*  

171. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP021815 (Sinorhizobium meliloti strain M270 plasmid accessoryA, complete sequence) position: , mismatch: 7, identity: 0.759

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
acgccacgctcgcgatcgccgcttacgga	Protospacer
.****.***************** ..*  

172. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP021816 (Sinorhizobium meliloti strain M270 plasmid accessoryB, complete sequence) position: , mismatch: 7, identity: 0.759

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
acgccacgctcgcgatcgccgcttacgga	Protospacer
.****.***************** ..*  

173. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP021817 (Sinorhizobium meliloti strain M270 plasmid accessoryC, complete sequence) position: , mismatch: 7, identity: 0.759

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
acgccacgctcgcgatcgccgcttacgga	Protospacer
.****.***************** ..*  

174. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_AP014812 (Methylorubrum populi strain P-1M plasmid pMPPM03, complete sequence) position: , mismatch: 7, identity: 0.759

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
ttgtcgcgctcgcgattgccgccggtgat	Protospacer
 .*.************.*****.**** .

175. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP013345 (Sphingopyxis macrogoltabida strain 203N plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.759

----gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
aacagca----gctcgcgatcgccgccggtgct	Protospacer
    **.    ***************.*****.

176. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP012641 (Massilia sp. WG5 plasmid unnamed 1, complete sequence) position: , mismatch: 7, identity: 0.759

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
tcgccgcactcgcggtcgccgctgaggat	Protospacer
 ******.******.*********. * .

177. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP022363 (Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence) position: , mismatch: 7, identity: 0.759

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgcggtcgcgatcgccgacaggacg	Protospacer
******** ************ ..* .* 

178. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_AP022607 (Mycobacterium branderi strain JCM 12687 plasmid pJCM12687) position: , mismatch: 7, identity: 0.759

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgcgcttgcgatcgcctctagctgg	Protospacer
**********.********* **.*.   

179. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_AP022607 (Mycobacterium branderi strain JCM 12687 plasmid pJCM12687) position: , mismatch: 7, identity: 0.759

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
gcgccgcgcttgcgatcgcctctagctgg	Protospacer
**********.********* **.*.   

180. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP015221 (Rhodococcus sp. PBTS 2 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.759

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
acgccgcgctctcgatcgccgccgtactc	Protospacer
.********** **********.*   .*

181. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP020812 (Mycobacterium dioxanotrophicus strain PH-06 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.759

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
acgccgcgctctcgatcgccgccgtactc	Protospacer
.********** **********.*   .*

182. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP020813 (Mycobacterium dioxanotrophicus strain PH-06 plasmid unnamed4, complete sequence) position: , mismatch: 7, identity: 0.759

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
acgccgcgctctcgatcgccgccgtactc	Protospacer
.********** **********.*   .*

183. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP034156 (Rhodococcus sp. NJ-530 plasmid unnamed4, complete sequence) position: , mismatch: 7, identity: 0.759

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
acgccgcgctctcgatcgccgccgtactc	Protospacer
.********** **********.*   .*

184. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to KR053201 (Gordonia phage GTE8, complete genome) position: , mismatch: 7, identity: 0.759

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
tcgccgcgatcgcgatcggcgctgccggt	Protospacer
 ******* ********* ***** .* .

185. spacer 7.9|4612077|33|NZ_AP022614|CRT matches to NZ_CP049794 (Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.758

gcacccgccgtgctggcgtcgctgaatccgccg	CRISPR spacer
gcacccgccgcgctggcgccgctgcgcagcccg	Protospacer
**********.*******.***** ..   ***

186. spacer 7.9|4612077|33|NZ_AP022614|CRT matches to NZ_CP049792 (Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.758

gcacccgccgtgctggcgtcgctgaatccgccg	CRISPR spacer
gcacccgccgcgctggcgccgctgcgcagcccg	Protospacer
**********.*******.***** ..   ***

187. spacer 7.9|4612077|33|NZ_AP022614|CRT matches to NZ_CP049790 (Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.758

gcacccgccgtgctggcgtcgctgaatccgccg	CRISPR spacer
gcacccgccgcgctggcgccgctgcgcagcccg	Protospacer
**********.*******.***** ..   ***

188. spacer 7.9|4612077|33|NZ_AP022614|CRT matches to NZ_CP016915 (Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.758

gcacccgccgtgctggcgtcgctgaatccgccg	CRISPR spacer
gcacccgccgcgctggcgccgctgcgcagcccg	Protospacer
**********.*******.***** ..   ***

189. spacer 7.10|4612128|30|NZ_AP022614|CRT matches to NZ_CP021798 (Sinorhizobium meliloti strain USDA1106 plasmid psymA, complete sequence) position: , mismatch: 8, identity: 0.733

tcgccggagaacaagccgcccatcccaccg	CRISPR spacer
acgacggagaacatgccgcccatctcgatc	Protospacer
 ** ********* **********.*. . 

190. spacer 7.10|4612128|30|NZ_AP022614|CRT matches to CP054917 (Streptomyces sp. NA02950 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

tcgccggagaacaagccgcccatcccaccg	CRISPR spacer
aagccggagaacaagccgcgcacccggcgc	Protospacer
  ***************** **.** .*  

191. spacer 7.10|4612128|30|NZ_AP022614|CRT matches to NC_003037 (Sinorhizobium meliloti 1021 plasmid pSymA, complete sequence) position: , mismatch: 8, identity: 0.733

tcgccggagaacaagccgcccatcccaccg	CRISPR spacer
acgacggagaacatgccgcccatctcgatc	Protospacer
 ** ********* **********.*. . 

192. spacer 7.10|4612128|30|NZ_AP022614|CRT matches to NZ_CP019483 (Sinorhizobium meliloti strain B401 plasmid pSymA, complete sequence) position: , mismatch: 8, identity: 0.733

tcgccggagaacaagccgcccatcccaccg	CRISPR spacer
acgacggagaacatgccgcccatctcgatc	Protospacer
 ** ********* **********.*. . 

193. spacer 7.10|4612128|30|NZ_AP022614|CRT matches to NZ_CP019486 (Sinorhizobium meliloti strain B399 plasmid pSymA, complete sequence) position: , mismatch: 8, identity: 0.733

tcgccggagaacaagccgcccatcccaccg	CRISPR spacer
acgacggagaacatgccgcccatctcgatc	Protospacer
 ** ********* **********.*. . 

194. spacer 7.10|4612128|30|NZ_AP022614|CRT matches to NC_020527 (Sinorhizobium meliloti 2011 plasmid pSymA, complete sequence) position: , mismatch: 8, identity: 0.733

tcgccggagaacaagccgcccatcccaccg	CRISPR spacer
acgacggagaacatgccgcccatctcgatc	Protospacer
 ** ********* **********.*. . 

195. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP039918 (Agrobacterium tumefaciens strain CFBP6626 plasmid pAtCFBP6626a, complete sequence) position: , mismatch: 8, identity: 0.724

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
ccgccgcgctcgcgctctccgctgcaata	Protospacer
 ************* ** ******  .. 

196. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to LR606153 (Rhizobium sp. Q54 genome assembly, plasmid: 10) position: , mismatch: 8, identity: 0.724

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
ccgccgcgctcgcgctctccgctgcaata	Protospacer
 ************* ** ******  .. 

197. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP013110 (Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence) position: , mismatch: 8, identity: 0.724

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
aacacgcgctcgagatcgccgctggggat	Protospacer
.   ******** ************ * .

198. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP013054 (Sinorhizobium americanum CCGM7 plasmid C, complete sequence) position: , mismatch: 8, identity: 0.724

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
aacacgcgctcgagatcgccgctggggat	Protospacer
.   ******** ************ * .

199. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to NZ_CP046575 (Rhodococcus sp. WAY2 plasmid pRWAY03, complete sequence) position: , mismatch: 8, identity: 0.724

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
acgccacgctcgcgatcgccgccctctcg	Protospacer
.****.****************.  . * 

200. spacer 8.1|4937523|29|NZ_AP022614|CRISPRCasFinder matches to MN234172 (Mycobacterium phage ThulaThula, complete genome) position: , mismatch: 8, identity: 0.724

gcgccgcgctcgcgatcgccgctggtgcc	CRISPR spacer
cggccgcactcgcgaacgccgctggacat	Protospacer
  *****.******* *********   .

201. spacer 3.3|1901552|33|NZ_AP022614|CRISPRCasFinder matches to NZ_CP031166 (Euzebya sp. DY32-46 plasmid pEDY32-46I, complete sequence) position: , mismatch: 9, identity: 0.727

accaggagcccaccgttgccaccgttcgggctg	CRISPR spacer
tcgtcaggcccacggttgccaccgttcgtgccg	Protospacer
 *   ..****** ************** **.*

202. spacer 4.1|2419552|34|NZ_AP022614|CRISPRCasFinder matches to AF068845 (Mycobacteriophage TM4, complete genome) position: , mismatch: 9, identity: 0.735

gaagcggcgcgaggaggagtcgggcaatccagct	CRISPR spacer
ggtgcgccgcgacgaggagtcgggcaaggtggcg	Protospacer
*. *** ***** **************  ..** 

203. spacer 4.1|2419552|34|NZ_AP022614|CRISPRCasFinder matches to NC_003387 (Mycobacterium phage TM4, complete genome) position: , mismatch: 9, identity: 0.735

gaagcggcgcgaggaggagtcgggcaatccagct	CRISPR spacer
ggtgcgccgcgacgaggagtcgggcaaggtggcg	Protospacer
*. *** ***** **************  ..** 

204. spacer 4.1|2419552|34|NZ_AP022614|CRISPRCasFinder matches to KC787101 (Mycobacterium phage 33D, partial genome) position: , mismatch: 9, identity: 0.735

gaagcggcgcgaggaggagtcgggcaatccagct	CRISPR spacer
ggtgcgccgcgacgaggagtcgggcaaggtggcg	Protospacer
*. *** ***** **************  ..** 

205. spacer 7.9|4612077|33|NZ_AP022614|CRT matches to NZ_CP021914 (Sagittula sp. P11 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.727

gcac-ccgccgtgctggcgtcgctgaatccgccg	CRISPR spacer
-tacaacgccatgatggcgtcgctgaatcccggc	Protospacer
 .**  ****.** ****************    

206. spacer 4.1|2419552|34|NZ_AP022614|CRISPRCasFinder matches to NZ_CP035709 (Sphaerotilus natans subsp. sulfidivorans strain D-507 plasmid pSna507_unt12, complete sequence) position: , mismatch: 10, identity: 0.706

gaagcggcgcgaggaggagtcgggcaatccagct	CRISPR spacer
caagtggcgcgaggaggagtggggcgacgcgcac	Protospacer
 ***.*************** ****.*. *.  .

207. spacer 3.2|1901486|39|NZ_AP022614|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 11, identity: 0.718

gcgttaccgccgttgccgccgggcttgccggcgacggtc	CRISPR spacer
ccgttgccgccgttgccgccggggttgccactaccgccg	Protospacer
 ****.***************** *****. .. ** . 

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	5058706 : 5110212	35	Corynebacterium_phage(25.0%)	integrase,transposase	attL 5065837:5065853|attR 5073483:5073499
DBSCAN-SWA_2	5192721 : 5295930	76	Staphylococcus_phage(46.15%)	integrase,transposase	attL 5217972:5217995|attR 5294638:5296055

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_AP022614|5058706:5110212|DBSCAN-SWA
GTCATGCGGTGGCCTCCGAAGCGGGGGTTGCTGGTGCGGGTGGGGTGGCGGCGAGGGTGGGCATGCCGAGCGGGACCGTGTGGGCCGCACGATGACGACGCACGATGGCGACCGCGTCGTTGATCTGCGCTCGCTCCGTGTCGTCGAGTTCGGCGATGTCGCCTTTGATCCTGTTGATCAGTCGCCGGATTCGGGTGATCTCCTCCTCGGTGGGGGTGGCGTCGGCGCGGGCCCATTCGTCCACTCCGTCGATGGTGGCGGCCAGCCGTTCGCGGGTGCGCAGCAGGTCGTCCAGGTATGCCTGCAGGTCGGGCAGGAAGGCGATGTTGGTGCGGAAGTGATCGCAGCCGACGCAGCGGAATCGGATCGGGCAGGCACCGCCGCCGGCCTTGACGTTGGTTGGTTCGGTGCAGGTGCCGTCGGGGACGGCGACCTCGCCGATGGCGTGGCGGGCGCGCTCGGAGTCCAGCAGGGCGTGTGCGTCACGCCAGATCCGGTTGCCGTGCCGGTCGAAGCTGAGCGTGGTGACCGTGTCGACGGCGTCGCGGCGGCGGTCCTCGCCGATGCGGTAGTAGCGGCGGGTCACCGAATAGCTTCGGTGATCGAGCAGTTCGGCCAGGACGTCGATCGGGATGCCGGCGTCGGCGTGGCGTTGGGCGTAGGAATGGCTTGTCTCCGCAGTGGCTGTGTGCGGTCGGGTTCGTGTTGCGTTTGACGTGGCCGATTCTCGGCGTGGAGTTCGTGACGCTGATCGCCGTTCGTGTGGCGATAACGCGAAACCGATTGTGATGGACGTCACTGCCGGGTCGGTCAGCATGGTCCCATTACCCTCTGCTGGTATTTCGGGCGATTCGACGCGAGGCGGGTGATGCCTGCCGCCGGGTCGTTGGCCGTGCGGAGCCGAAGGATCTCGTCGTGCTGGGCAGCGATCCGGGCCAGGGCCTGGCTTCGGAAGTTGGTGAGCTCCTGGATTGTCGAGTTGACGTGGGCGAGGTTGTTTTTCAGCTTCTCGACCTCCGTCTTGAGGCGTTCGATCTGTGCGGTTTTCGGGTCCGGGGTTTCTCCGGCCTGCTGAAGCTGCTGGAGGCGGTGCTCGAATTCGGCGCGTAGGTGTGCGTAGGGCCGGGTGCCGTAGAAGGCGGTGCGGTCGACCCCGGCTGATAGTGCGAGGGTCTTGATATCGCAGTTGCCGCCGGGTGAGATCTCGCCGCGCAGAAGCCGGTCCATGGCGGCGCGGATGCGGTTCTCGTTGTGGATGCGTTGGGCGGCAGTGATTCTCATGCCTGTTCCTCGGGTGCGCTGGTTCCTGTGGCAGTGTCGATGCTGGTGATGACCTGGACGGCGCGGTCGTAGTCGGCCTGCAGACGAGCGCGTTCGGCGGTTCGGGTTTTGCCGAGTTGGCCGAGGAAGGTTTTGGTGCGTTCGGCGTGCTCGGCCCAGACGGGCCGGTGGTGCTGGTGGTGGGTGGCCTGCGGGCAGCGTGCGGAGTCACACATGCCGATCATCGGCCGGTCCGCGGTCAGGGTGCCTGCAAGTTTCAGGCAGAGCGCGCGGGAGGGGTCGGTGAACCAGCAGTAGTTCGCTGGGCCGAGGTGCAGCGCCGTGGCGCGTTTGGACAGCAGGTTGAGGATGTCGCGGTCGTTGCGCTGGATCTTCGGCGCCGCAGTGGCTTTGGTGTTCGGGTCGGTGTCGATGGTGGCGAAGAATTCGGTCAGGCTGCGGGCGCCGGGTCCGGCGGGCAGGATGCCTTGCTGGTAGTTGCGGAACTCGGCCAGCACGAGCTTGAGTATGTGGTCGGCCTCGAGCTTGTTGACCTCGGCCAGCAACTCTGCTTGAGCGCCGCCCGGTCGAGCCGCGTAGCCTTCCGTTGTCGCCGCGGCGATATGTTTGAGGTGCAGTTTTGCGGCGAGGACACCGCCAGGCCGGTAAGCCATCTCCAGGGCAACCGTTCTTCTGAGCATACGCAGTGCTACTGGTTCGTCGGGGATCGGGACGAGTCCGAGACGGGCTCCGGCCGGGGAATTCACCCAGGCGCGGAACCAGAGGTAGCGGACTCGGAAGCTGAACCGGGACAGCAGGAGAACACCGTCACGCGGGTCGTCGTGGAGCTGCTCGATGAGTTCGATCGCGCGGTGGACCGGTTCGATGACGACCCATTCGTCGTCGGTGCCGCCGAGGCCCTGACCTTTGATGATTTTGCTGGCGATGCGATAGCACTTCAGGCCGGAGATCGGTTCCTCGACCCGGCGGCAGCCGACCCGCAGTTCCATCAGCTCACTGGCCCGCATTCCGGACGCGCCAGCCAGGACAACGATCGCTGCGGTGCGGGCGATGCCGACCATGGCGACCGCTTCGGACCGGTGCACTGGCAGTGTCCAAGGCAGCAAGGTCGCACCATCGGCGGCCGGGACTTCGGCGGCGTTGCGGCCGAAGATCTTCTCGACTCCGACGGTGTTGAGGGTGTCGATCAGCGGTTTGCGCAGTGTGGGCATCCATTTCGCCCAGAACTGGACGTATCCGGCCTGCCGCGCCAGGGTCCCGGTGGAGACCGGCAGCAGCGGGTCGTTCGCGTCCCAGCCAGCCTTGAGTCTGCGGTTGACGTCGTGTTCTTCGAGCATCGGCAGCGGTGTGTCGGTCGCCCTGTGGTCGGCCAGCAGCATCGTGATGTCGCTGACCATCGCCGGGGAGCCGTGACGAAGCCCGGGGGCTCCGGTAGCCCAGACACGGTCGATCTTGCGGATCTGCTCGTTCAGCTCGACAACGTGCGGGCCGAGGATCTGCACCAGGTGCAGGGCCGCGGCCAGCATCGGCTGCAGCACTTCGGCAGGAACGGCAGGTGTCTTGTTTCCGTCGCGACCAGAAGGCATTTCGGCGACCGCGGATGCTGTTGCGCCGCCCCAGGGGCGCAGATCGGCCGGAACCCGGTCGGCGGTGAACAGGTCACGGTAGTCGACCAGATCGACGATCATCTGCGCGGCTGCGCGCCGGACGCCTGGGCTCTGCTCGCCAACGATGACGCCGTCGGGGTCGATCACGTAGCGTCGGAACGCCAGGTATTCCTCGCAGAGGTGGGTGTCGAGCTCGGTGAGGGCAGTGATGCCCCGCTGATCGAGCCAGCCGAAGAACTTGCCGGCCTCGTAGAGGCGGCTGTAGCAGCTGGTCAGATGCAGTGGGGTGCGGTAGGCGCGTGGCAGACGGACCACGGCATTGTGATTCGGGGCCAGCAGCGCCAGGATCAGCTCCTTGGCGACCAGCCGCCAGCGGGTGTCGGTGATGGTGGTGAAGTCGAATCGGCGTCGGTAAAGGGCCATTTGGACCGGGAGCCCGACCACGTCGGTGAAATCCCACAGGTCGTCGTCGAATACCGGTCGTGGCGTGCCGCCCGGCAGCGTGAGCCCGGCGTCGCGGCAGATGTCCGCGCCGGTGAACGGCGACCGTGGTTGAACGCCGGGTGCTGCGGTCGCGATTGTGCTCGTCATGCGGTGCGTTCCTCTGGGCGCAAGGGGATTTCGTCGTCGCTGTCGGTGACGCGTGCGGCTGCGACAGCGAGTTCGGCGGGGTCGAAGCGGTCGAGGATCTGGTCGATCCGGGCGGCGTAGGGGCCGAAGACGGTCATGAAGTGGGCGGCGGGCATCTGCTGCCACTGGCGCGAGAAGAATGCCTTGAGCCGCAGCAGGTTCACTGCGTGCCGCGGAGCGAACACCGCCAGCGGGCAGAGCAGGCAGACCCAGGGACGTGCCGGGCATGGTTTGCCTGCCGGCCCGTGTAACCCGGCCAGCTGATCGGCGCAGGCTGCGGTGAACACATCCCGCGCGCCACCGACCAGCTCGGCGAGCACGCCTTCGTCGAGCTTCATCACCGCCAGCAGCTGCGGGTAACCCTCGGCGAGCGCCGCCGCGTCTTCCTCGGTGATCACGGCCGGAGGGTGCGCGCGGCGGAGGATGTCGTGCTGGGCGTCGGCGATGATCGTCTCGACGGCGTGGCGTTGACCGGGAGTCGTCGCCGACAGGTAGTGGTCACCCTCGACCGCGGGCGTGTGGTTCGGGTCGATCGTGGCGCGCGCATTCCCGGTCCAGGACTTCTTGTCCCGCATCGCGTGATGGGTGGTGCGGATGCGGGACCGGTGCAGTTTCATCGGCTGACCGTCGTCGCCGACGATGCCATGGCGGCGCATCCACCGGCCAATCGCGGACCGGTTCACGTCATCGAGGCGGCGGGAGTAGCCGGGCTGGCTCATCCCCAACCACAGCGTGGTGCGCTCGTCCGGCGGCACGAAGCTGCGCAACAGCGCCGAGTGCGCCAGCCACTGCTCGAGCAACCGCACCGCCGGCCGCGGCAACGTCGCGCTCTCGGCGGCGGTGCGCCGTTTGATATAGGACAGCAGAACAGTCGAATCCCCGGCCCAGTCGATGTCCCCGATGTCCAAGTCGGCGATGCCGTCGGGGACGATGCCGGAATAGATCCCGAACAGCAGCCGGTAGGCGATCACGACCTCGAGATGCGGGAACATCGCCAGCGCAGCCTCGTGGAAGACAGCGATGACTCCTCGATGACGGAAAACGTTGATGGACATGCCAATTTCCTCAGCAGCTTCGCTGCTGCCAAGCGGGCCGAGTGTCGACAACAGCCAGCAGAAGTTCTGATGAGTCCACGCACCCGTGCCCGGATGCCGCCCTCCGGCGGCGGACGCCAGCGCGCGCCGATGTGCCGCGTAGGAGTCGTCGACCTGCTGTCGGCAGGCCATGGTCAGCCGCTGCCATGCGCCCTCGGAATAGGGCGGCAACGGGCGCCGATTGCGCTGAATGTTGAAGTGCCGCCCTGCGGCCAGCTCCAGCACCCCCTCGCCGAGACGGCCGCCGGATCGCGCATAACCTTCCACCAAGTACCGAGTCAGCGCCTCCAGCCAGTTCGGGCCCGCCATCCAGAACTGCGCCAGCTGTCCGCGCCGCAGATCGCCGACACCGCCGGTGAAACCCTGATCAGAAAGTGTTCGCACCATCCTGTGCAACCCACGCACGTACTGGTCGACGGTGCCAGCAGTATCGACGCTGCCGTGAGGATGGATCAGCTCCACCAACCCGGTGGCCAGATCACGCACCAACCCGGGGTTCGGCAACCCCGTGAGATCGAATGCAGCTCTGCTGCCGTCGCTGAACACGCAGGCCAAACGCAGCGGATCATCGAGCACCGTCGTCGGCATCACAGCTCCTCTTCGGTGTCGTCGTCGAACTCGGCGTCGGCTTCCCGCTGTGCGGCGGTATCCTCGGTGAGTCCCGCTGCGGCTCCGGCGGTTTCGTAGGCTTGCCGGTAAATCCGCGTCGTATCAAGACGTTTCAGGTATTTCTCGGTCGTCAGAACCGTGGAATGCCCGAGCAAATCGCGCAGCACCAGCAGCGGGTCGGCCTTGGTCAGGTAGAACACCAGCGCTGCGTCGGCGTCGGTGTCGCATACCAGCTTCGCTGCCTGTCGGTAATAGCCGGTCACCAGATATTCCAGCGTCTGCATCGAGAACGAGTGGCGGAGTCGGTGCGGGTGGACGTGCGGGAACCGTGGTTCGAACCGTGCGCGGATCCGGTCGGAGGTGCGTTCGAACACCGTCGCCCACGCCGTGAACGGGCCACCATCACCCTTCACCGCTAGCAGGCACGACCCGCCCTCGGGTGCCACCAGCCGCCGTCGCTCGGCCGGGGTGAGCGACTCCCAGGACCGGCGGACGCCGTTGATCCGGCCGCCACGGGCGTCCGGTTCGGTGACCTGCAGCGGTTCGCCCCGGCGTCGTGGTGGCCGCCAGGCCGATCCGTCGGTGACGGCAGCGCGGTCGAGCTGCAGGTAGTCGTGCAGCCCGGCCAAGGCGTCGTAGGAGATCCAGGTGGTTCTGAACTTGCGGCCCTTGGTGATTCCCGCAGGCACCGGAAACGGGATCGGGATCACCGTCGGCGCCGGCGGCAGAGCCGGGATTTCCCACGGCAGCAGATGTGTGAACTCGCCCAGCCGCAACCCGGTCGCCAGCGCGAGGTCCCCGATCGCGGCGTTGCGGGTCATCTCCCGGCCCGCGAACCCGGTGTCGCGGGTGCCATCCGGCGCCAAACCGCGCAACCCCTTCCGGAACAGGTCGGTGAAGTCCGGCTCCAAATACTTGATGGTCACATGCGGTTTCGGGGTGCGGCGCACCGCCAAGTTCACCCGGACATCGCGGCCGGTGCCGGCGAAGACCGCTCGCGCGGATCGGTAGGTGAACGGCTCCGCCTCGGCGTATCCCTCGTCCATCGCCCACCGGTAGAACAGCGACAGGATGCTCATGTGCTGCGCCCACGTGGTCGCCGCGAATCTCGCCCGGATTGCTCCGGCGGCGCGGTGCTCGGCGTATCGGCTCAGCCCTGCCTTGAGCCGGTCTCGCGAATCGAACAGGCCCACACCGTGTTCGGCGAGGAATTCCGTCCATTCCTTGACCGCCCGCGCGTAGTTCTCCCACGAACTCGGCGCCGGAGCCCCGCTGGCCGGAAGCAGCCGCAACCACCGATTGATCACCGTCGTCGGCCGCGGCACGGCCGGGCCGTCCTCGAACAGCAAGTCGTCATCGATCAGCACCGGCATCCCCTCTGGGATCACCGGCCGGTGCTCGACACCCCAGGACTGCCAGCCCTGCGACGAGAAAAAGCTCAAGATCACGACTGGAGACCATACAAACACCACACGGCCTCACCAAAGCAGAAACGCCGAGCACGCCCGGGCCTTTCAGGCCAATCGCAACACGGGAACTAAGCGGGGACAATGTGCCGGTAGGCGTAGGGCACGATCTTGGTCATGTCAAACTCGACTCCATCGCGGGTGCGCAGTGTCGGCAGGTCGGCCACCCAGTCGCGGTGGCGCGCCTGCAGGGTGGTTCTGCTGATTGCCTTGTGCCCGTCGGGATTTCGATAGGGCGTGGGCAGCAGCTTCAGCTTCGCGGCCAGGGTGTGGGGGAAGCGTTGACGGATTCGTTGTTGTTGGCCGGTGATCACCGCGGCGGTGGCCGTGCTGATCGGCAGCCGTCGGCCGAGCCGGTTGGCTTTGATGTTGTCGTAGACCAGTACGTCGCCGCCGTCTTTGTCGCGGGCCAGGCAATCCAGCGGCAGATTGAGGATGTCCTCGGGGCGGCGGCCGGTGTCGATGCCGATCTGGGTGGCGACCCTGACCTCGACGGGTTCGAGGGAGTCGAGGTTGGCGCACAGGACGGCCATGATCTCCGGTGGCAGGCATCGGCCGGGCTCGCCGCGTTCGGGGTCGGCGGGGATGTCGGCGCGTTCGATGGCGCAGTCGCCGGGCAACCCGGCCGCCGGCCGTCCGGTTCTCGTCAGCCCCAGGGATCGGATCCCGGCCAACACCTGCCGCATGTCACGGCAGATCATGTTGCGGCGGTAGCGACCGATCTGGCCGGTGAACTCCAGATGGCCGAGCCGGTTGAGGAATCCCTCCAAGTCGGTCCGGCCCAGCGCGGTCGGGTCAAGCCCGTGATCGGGTCGGCGATGCAAGTGCTCGGACAGCAGCCCGATGCTGTTGATCTTGCCGCGAACGCGAGAGGCGCCGCTGCCGCGGTGCTGGGGCAGTTGCTCGGCAGCCCACCGCTTCGCGGCCCCGGCCAGCCAGGGCTGGGTGATCTTGGTGAACGACAGCGTGCCGGGGTACCGAAGATCGCCAGATCCCAGCGGTCCTTATCCTGCTCGACACCCGGATCGGCCAACACGCGGCGGGCGTCGCGGGCGAACGAGGCCAGCACCGAGCGTGCACGCTTGCCGGGAGCCAGGCCCGGATCGCAGTCGTGGATCGAGCCGACCTGGTGGCGACGCAGCGTGTCGCAGACCGCTCGCAGCACAACGTCGGTGAGCCGCAAGCCATCCCTAACACGGGTCTGCAAGCCCGTCAGCACTTCCACAACTACCAGGGAAGGCAGCGCCCGCAGGTTGACCTGCCCCGGCTCGGCCACGCCCGATTCCCGGACCCGCCACCACTGTTCATCGAGTTCGGCATGCTCTTGCTGGTCCACGCTCCATCGCTGATAGTGGGTCGTGCAGTAGCCGATCGCGCCGTCGGCCGTGCGGGTGCACGCCGGCACCAGGCATGCCGGCAGCGGCGGCCTTGGCCGCACTCGCGGATCGCTCACGAACTGTTCCAGCGAGATCGGGATGCGCCTGCCCCGGAACTGTTGGGCGTGCGGTTCACACATCACCGCGTCCCGCACCGTCGGCGTGCACCGGCACTGCGGGACGGCGCAGCGTTCCGCGGGAACCGGTGCGGCGGGCAGGCTTTCGGCAGCGGCGATGTCCTCGACGCTCATGCCCATGCCGGTCAGCCTGGTGAAACATCGGTGGCAGATCTCGGGGGCGTCGTTGTGGACGGTTCCGACGCATCGTTCCACCCGGCACACCTTCCGGCCGAGCAGCCGATGCTGCGCGGGCAAGTACAGCACCCGGGTCACCGGATCCCATCCGGCCTCGTCAAGCAGTCCTTGGTCCAGCGCCCTGGCCAGGTGCGTGGCCGCGCCACTCAGGGCGGCCCCGTCCAACACATGCGCGAACTTGCAGGATTCCTCATCGCCCGGGATCGTCCTGGCCGACGTCACGGCGGTCACCGGCTCGCTCCGGTCTGTTCGCGGGGGCTGGGCACCGCGTCCACCGCGGCCCGCAGTCGAGATGCGTCCGGATGCAGGTAGATCTGGGACGAGGAGACAGCCGCGTGTCCGAGCAAATCAGCGACCACGTCGATACCGGCCCCGGCGTCGACGACGTTGCTGCCGTAGGCGTGTCGCAGCTGGTGCGGGCGGACCGGGGTGTCCAATCCGGCCCGGCGGGAGACCGCTGCCATCAGCTCGCCGATCGCGTCGGGCCGCATCGGCGCGCCGACGCGGCCGCGGAACAGGTTGACGAACACGAAATCACTACCCGCCGCGGCCGGAACTCGCATGCGCTCGAACTCGTAGACGTCGAATGCTTGCACGACAAGGAAATCCAGCGGCACCACCCGCTGTCGGCGCGATTTGGCCCACGCCCCGTTCGGGTTGTCGTCTCGGCGCACCACATGCAGATGCGCCCGAGCGACCTCGCATCCCAACCGGCGCGAATCCACCAGCAGGTGCACATCACTGCGCCGCAGCCCGCACACCTCGCCCCGACGCAGCCCGCCCCTGGCCATCAGCAGCACGATCAGCTTGTCCCGCGTGGACCGGCAGGCCCGCAGCAGCGCGACGATCTGCTCATCGCTGGCCCGATCGATCGTCGTTTCCGGTTCCCGCAACCGGTGCCGGGCCCGCATCCGCCATGCCAGGTGGCCATCGTCGTTGCGGGCTTCCGCCGGCAGGTCTCGGTCATCGGCCACCTCGTACAGCATCGACACCAAACCCGCCGAGCCGTTGCCGGTCGCGACCGCGTGCACCACCATCCCCCGCACCGCGGTGAGCACCCCGTTGATCCGCGATGGGCCCCGCGCCGGGGCGGCCCCCGGACCGGCCAACACCACTCCCGAAGCGACGTCATCGACGCCCGCTGGCCAGCGGTCCGGCATGGGCCAGCCACGTCATGAACAACGCGAACTGCTCGACACCGGCCTGCCAGGACCGGCCCGTCCTGGCGCACCAGCGCAGGAACAACGCGATCGCGTGTGCATACGCCTTCGTCGTGGATTCCGCGCCGTCGCGGCCGAACCGCTGATGCCGCAGATACTCATCGGCGATGCCGACTACCTGCAGATCCTCATCCAGCACCGTCCAATACCGTTGCCCGGACGGCAAACTCACCGGAAACGCTCGCATGGGCCCTCGCTTTCAAGTCGACAGTCAGAAACGACTACCAGCCACGAGCACCACACCCACGGAGAAACGCCGCACCGCCCACCAGATCACCCACTACGAGCGACGTCATGCAACAGGTCGCAGACCCCCGGAGAAGGCTTGCGGCGCCAAGAGGCGGTGGGGCTAGACCTGGTGGATCTGAGATCGAATCCAAAGCTACCGTCCTACGGGCGTTTTGGCGGCGTATTCGTCCGATTCGGAAAAGCGTCCCGCGGTAGTTCGCCGAAGCGACGCGTCGTGCTGACGGTGCCGGAAATGGACTGGATTGTCCAGGTTTTCGAGTCCTACCTGGAGGAGGTTCGTCCATGCTTTCGAGCGGGCCGGCATCCGGCGTTATGGGTCACCGAACGTTGCGGCCGTCTCTCCAGACGCGCCGCGAACGAGGCCTTTGTGGCTGCGCGTGACGCCGCGGGGTTGCCGCAGGAGCTGGACCTGCATTCGCTGCGCCAGACCCTACGTCACACACCTGACCGAATTCGATTACCCGGAGCGCTTCGTGCAAGTTCTCTCGAGCCCGCACAGGGGTGTCCACGACGTGCAACACGCACGTGGCGTTGGCGGCGATCTTCGTGGCGGAGGTGGTTATCTGCAGCGGTCCATCACGCAGATTCCACGGAGGTTTGATGCTTGTGCAACGGGTACTGATGCCCACTTCGTCGCTTGAATCCTGGACGGTCCTCGGCGACGGAGGCGGCTCGGTGGAGCCAATCGAGCGCTACCTGGCCTATCTGACCGACATCGAGCGGTCCCCGAACACGGTCAAGGCCTATGCGCACGACCTGAAGGACTGGTTCGTCTTCCTCGACGCTCGCAGCCTGAACTGGCGCGAGGTCCGATTGGAGGATCTCGGGGAGTTCGTGTCCTGGCTGCGGCTGCCGCCGGCTGGCCGGGCTGGCGCAGTGGTGCAGTTGCCCTCGGCTGAGCATCACTGCTCTGCGGGAACCGTCAACCGGAAGCTGGCGGCGATCAGCGGCCTCTACACGTTTCACGCCCGGCACGGAGTCGACCTCGGCGACTTGGTCACTGAACTGCACCCAGGTCGGCGCCGGCGCTCGGGATGGAAGCCGTTCCTCTACCACCTGAGCAGCGGCCAGCCGGAGCGGCGGCGCACGATCAAGCTCCGGACCCCGCGTCAGCATCCGACCATTCTGACCGCCGGTCAGGTGCAGGCGATCCTAGATGCCTGCATCCACCTGCGGGATCGCTTGTTGTGGGCGTTGTTGTGGGACACAGGGATTCGGATTGGTGAAGCGCTAGGTCTGCGTCACGAGGACGTGGCCGCTGCCGAGGGTGAGTTGACGGTCGCGCCGCGATCCAACGACAACAGGGCGCGCGCCAAGTCGGCGACACCGCGCACCATCCCGATCAGCCCGCAGCTCATCCGCCTCTACGCCGACTACCTGCACGACGAATACGGCGATCTGGACTCCGACTACGTGTTCGTCAACCTCTGGGGCGAACCGTTCGGGCACCCGTGGGGCTATCCCGCGGTCTACGACCTGGTGTTGCGGCTGCGCCGGAGCACCGGCATCGACTTCGATCCCCACTGGTATCGGCACACCTACGCCACGCGTTTGCTCCGCCAGAACACCCCGATCGAGGTCGTCAGCACGCTGCTGGGGCACTCCTCGATCGCGACCACGATGGACATTTACGGGCATCTGTCCGTCGAGGACGCCCGCCGGGCTCTGGAGGCGGCCGGCTTCCTGACCGGGCAGGAGGTGCAGTGGTGACCGCGGCAGTCCCGCCGCTACCGTCGGCTGCGGCTCCGGGCTTGCTGCGCAAGCTGGTGGCCGCGGTTCGACCGGAGTTCCGGGTGGACATCCTCGTTCCCGAGCGTGGTGCGCTGGTGTTCGACACCGCGCCGTGCCGGGTGCCGGGCTGCGTGCGCCAACCGCGCACCCGCGGGCTCTGCAAAGGCCACTACGTCGGTTGGCAGCAAGAAGGCCGCCCGGACATCGACGTGTTCGCCACGACTGCAGCACCGGAAGGGCTCGGGCGCAAAGAGCTCACGGTCTGCGCCGTCCAGGGCTGCCGGTACGGAGGTGCTCGCCGGGGTTTATGCCCACGCCACCAAGGGTTTTGGGAACGGTCCGGCATCGCCGACCGAGACGTATGGCTGGCTGCCGTTGCTCCGGTGGATGATCCCGATCATCCCGTCTGCGCGTTGTCCTATTGCACGCTATGGACGCAGGGACGGTCGCCGTTCTGCGTCAATCATCGGTCCCGATGGGCAGCGGTGGGATGTCCCGACATCGACGAGTTCATCGTGCTCTGCGAGTCCTATGGCGACGACCGGTTCGACTTCCGACCGTTCGGTGATCGCCGACAGCTCAAATTGGAGATGCAGTACGCGCTGCAGTGCCGGCACGATGAACGCCAGGTCAAGACTCCCGCTGCCGTCGCGCGTCCTGTCATCGCACTCACGGCCGCCAGTGGGGTGGCCTCGCTGCTGGACTGGCCGATGGCACGTTGGATCGAGTTCTTCGACGCCAACCACGCTGCGCAACACGGCCAGAACGGACAGCTGGCGTTTCTGCGTTACGCCTATCGCTGTCTGGAGGACCTGCACTGCGGCAGCGGGTGGGAGGCCGAGTTCCCGCGCGACGTGTGGGAGCTGCACCGGCTCGGCGTCGAGGGCCGCAAGCGGCTGCGCTTCGACGGCATTGCGCAACCGTGGCTGCGGGATCTGGCCAAGCGGTTCGCCCGCTGGCGGTTAAGCATCGGACGCAGCCCCAACCAGACCTACATCGACGTCCAGGCGGTGACGCGTTTGGCCGGCTTCTTGGCGTCCCCGCCGGTCGACATCACCAGCCTGGCCGGCATCAACCGCGCGGTATTGGAGCGCTACCTGGCCGACCTGTCCACCGACCCCCGGGCACTGCACTCCCGCAGCCGCGACATCAGCTCGCTCGGTGCGTTCCTCGACGCGATCCGCCGCCACGAGTGGGACCACGACCTGCCCGCGAGTGCCGCGTTCTATCCCGACGACTTCCCCAAACCCGCGAAACGCCTGCCCCGCGGGCTGGCCGAGCACATCATGGCCCAGGTCGAACAGCCCGCGAACCTCGACGGATGGAACAACCCCGAGAGTCGGCTGCTCACGATCATCCTGATGCGCTGCGGACTGCGCGTCGGTGACGCCACCAAGATCGCCTTCGACTGCGTCATCCGTGGCGGCGACGGAGCTCCCTATCTGCGCTACACCAACGGCAAGATGAAACGCGAAGCTCTCGTCCCGATCGACGAGGAAGTCGAGCAGGCCATCGCCGAGCAACAACAGCGGATCCTGCGCCGCTGGACCAACGGCAGCCCCTGGCTGTTCGCCGCTCCGAAGATGAACCCAGACGGCCGCCGGCCGCTGACTACGCCCTCCTACCGCGGCCAGCTACGGGACTGGCTGGCGCGCTGCGAGATCCGCGACGAGCACGGCCGTCCAGTGCATCTGACTCCGCACCAATGGCGGCACACCTTTGTTATCTGTACTGGCAAGGAGCGCGTGAGCTACGTGAGTTCGGCGGCGTGACACGCCGGTGCCTTACGAATATCCGGTACTTTCAGGCACGGCCGTTACGTTTGTCACGTGAACTCGTTCCACGCTGAACGAGCGGTTTCACCCCTCGATGGATCCGAGGTGTGGGTGGTGCTTGACACCGGGTTGGTGATGCACCGGGAGGCCAGCGATTTCCTGCGGGCGCTGCATGGGGCCGGGCGTTCGATCCACACGATCCGTGCCTATGCCGGGCGGGTGGCGAGTTTCCTGGGATGGTGCGCCGATCAGGGGGTGGAGTGGTCGTCCATCAGTCTGCCGGGATTGGCCCGTTTCAAGCATTTCATCGAAGCCACCCGCGCCGGGATGGGCGGTTGCGTTCGGGCGCAACGGTAAACGCGATCCTGACCGCGGTGTGTGAGTTCTTACGGTTCTGCGCCAGGACCGGCGTGATCGAGCAGGCCGTCGCCAACCGGTTGTCTGAACCCCGCTGGCTGCGGTTCACCCCGCCGGGTTTTGATGCTGGAGAATCCGGCCAGTTCCGGATGGTGCGGACCCGCACGCTCAAGGCGAGGGCGGAAGCGGTATTTCCCGAGGCGTTTACACCCGAGCAAGCCGAACGGGTCGCGGCGTGTTGTCGCCGGCCGCGGGAACGATTCATGGTGGCGCTGCTGCGGGATGGGGGCTTGCGGATCGGAGAAGCTCTCGGATTGCGCCGATCCGATCTGCACCTGCTTCCCGATTCGCGGCGGGTGGGTTGCACGGTGCTGGGAGCTCACGTTCACGTGCGGCACCGGGCCAATCCCAATGGCGCGCTGGCGAAGTCGCGGTTTCCCCGCACCGTGCCGACGAGCCAGGCGGTGCTGTCGACGTACGCGGACTACCAATTCGAACGTACGGAGATCCTCGGCGGCGACGACTGCGACATGGTGTTTGTCAACCTCTACCATGAGCCGCTGGGCGTGCCGATGACCTATCGTGCGGCGAAACGGTTCTTCGAACGGCTGGCCACCGACTGCGGGTTTGCGGTGCGCCCTCATATGTTTCGGCACACGGCGGCCACGAACTGGGTGCGTGCCGGGGTTGATCTTGATGTCGTGCAGCGGCTGTTGGGGCATGCCGCGCTTGCCTCGACCGCTGTTTACCTGCACGCACGAGATGAGGATAAGCGCCGAGCCGTGGAGGCTGTCGCCGCCGGGGAGCGCTTTCGATGACCGCGCCGGTGTCGCGTCTGCTGGTCGGCACCGACGCCGACCAGGGGTTGGTGAGTGACGACGCCAGCTGGCTGCAATGGCTGTCTGCCCATACCGATGCCGCGTGGCGGCCGGGCGAATGGGACGGGTCGCTGTGGCTGTTCACCGGCGATTTGGACAGCGATCGGACCGCTGCGTGGCGGTGTCGTACTCCGGGCTGTCCTACGGCGGCACGGGGCTTTAACGGCCGCTGTTCGAGTTGTCGGCGGGCGGGCGGCGGCCGGTGTCTGCGAGGAGGAGTTCGACCGCGCGCCTCGGCGTCGCCCGACCCGCCCGGTTGCCCGAGGTGACTGCGTGGTGCCCGACTGCGGGGGCGAGTTGCATTGCCGTGGCCTGTGTTTCCGGCATGAGCGGGCCTGGCGTAAGGCCGGTGGCGGGCCGCTGGAGGAGTTCATCGCGCAGGCTCGGCCGCTGATCGGTACCGAGCCGTGCCTGGTCGCAGGTTGCGGCCGCGAACGGGTAACCCGGCGAGGCCTGTGCCGGTTCCACGGCAATCGGCTGGCGCGGCAACGCAACCCTGCGTCGATGTCGCAAGAAGAGCTGGCCGCGTGGGTCGCCGACGAGAAGCCCCGGATCTCGGCCCACCAGTTTTCGTTGGCTGGCCTGCCCGAGCTGGTGCGCTTCGAGTTGCTTTATGCGCTGCAACGCCGCGATGAGGCGCCGCCTCCGTTGGACCCGCTGCAGGTGCGGATCCTCATCAGCCGCCTGGTGGGGGCCAGCTCGCTCCGTCACGCCGATCCCGAAGCGGTGTGTGAAAGCGGTGGCGTGCAATACAACTCGGCCATCAAGGGCTTGTTCCGCGACCTGCGCCGTCATCTGGAACGAGCCTGGACCCAGTACACCGGCACCGACCCTTATGCCGGCAACGTGTGGCGCGTCGAGCTGCTGGACCTGCAGTCCAACGGCTCGCGCCGCTGGCCCGCCACCAAGGGGACCATCGACTTCGGTCCTATCGAGCTGGGTTGGCTACGCGAGGTGCTCAAGGACTGGGCCCGCAACACCCGGCCCTACCTGCAAGGGCTGCGCCAAGCGCTGCGGGCCTGCCACGTCGCCTCCCAAACGCTGGTGGCCTGCGGCCGCGCCGACCCGGCCAGCCTGGGCGCGGGCGACTTCGTCCTGGTCGAGCAGGCCATCGTCGAGCAACGCCGCACCGATGGCTCTCCCCACTCCGCCTCACACCGCACCCAGCTGCTGCGGCTGTTCTGTGCGGTGATCGAGCATGGCCGCGCCAACGCGCTGATGACCGACGTGCCCGACCCGTTCCGACCACCCCAGCGCCGTCACCGGGTGATCGAGGACGCCAACGAGGAACAGCTGGGAAAAGCACTGCCCGACATGGTGATTCGCCAGCTCGACCAGCACCTTGACCTGTTGGGTCCGGCGGGCCGACACGGCTCGATGAGCGCCCCGGACCTGCAGGCAATGCACCGGACCATCTACCAGATCCTGCGTGACACCGGCCGCCGCCCTGGTGAGATCGTCAGCCTCAAGATCGGCTGCCTCGAGGTCATCGACGGCCAACACAACCTGATCTATGACAACCACAAGGCCGCCCGACTGCGTCGACGCCTGCCCATCACAACCGACACCGCCGAGATCATCGCGGCCTGGCAGCGTCACCGCACGCAGCTGCCCACCGCGCCGGCGACCCGCCAGTGGCTATTCCCATCCCCGCTGTTGCGCTCCCGGCAGGCCCGCGGTCACTTGACCGCCTCCTGCGTCGGGGTGGCGTTTCGGACTTGGACGCGCTCGATGATTGACGGCTGCACGCTACGCTCAGCGCTGCATCAGCTCATTGCGACGCTTGGCTACTACTCGGTCACCCACAAACGTAAGCAGCAGGCTATCCGTGCCGTCGGATCCTTGGCCATAGACGCCTCGGGCAACCCGTCCTCGTTTGCCGACCCGCTGGCCTACGAACGGGCATCGGTGTCGGTCCCGTTCGGTAACTGCACCGAACCGTCCAACGTCAAGGCCGGTGGCGGTGCCTGCCCGATCCGATTCCAGTGCGCGGGCTGCGGCTTTATCGCCCGGACCCGTCATATCTTCCCGCCCTCGAAGAGCACATCCACTCGCTTCAGGCGGACCGGGAGACCGCCCGGGCAATGGCGGCCGCTGACTACGTGGTCGCCAACATGAGCACCGAGATCGACGCGTTCACCCGCGTGGTCGACACCATGCGGCGCCGCTCGCCGAACTCGGCCCCGAGCAGCGAGCCGAGGTGGAGGAGTCCAGCCGGATCCTGCGCCGCGCCCGGGCCGCCCGCCGCCTCCCGCTCATCGTCACCTCGGCCAAGGACGCCGGATGAGCGCCACCGCGGCCAACCAGATCCGGTCCGCAGCGCTGAAAGCGGCCCGCGCCAAAGACAGCCAGCGCAAGCGTCAGCGCACGCTAGCTGCGCTGCAAACCCTTGAAACCACCGGCGCGCCGATCACTTTCACCGCGGTGGCCAAGGCCGCCGGGGTGTCCACCTGGCTGGTCTACGCCGACGGAATCCGCGAACACATCGACGCGGCTCGACACCGCCAGAGCAACCATCACCGCCGGACCGACACGCCGGCAGCCTCCAGCACGCACCCGGCGACGCCGGACAGCCTGCGCGCCGACCTGGCCATCGCCCGGGAGCAGATCAAGACGCTACGCACCGAACGGGACAAACTCCAGCAGCGCCTGCGCCTGCAACTCGGTGCCGAACTCGAAGCACCCGACCGGGCTCACCTAACCGCGCGGGTCGTCGACCTCGAGACCATCAACCGTCAACTCGTCGCCGAACGCGACGCGCGCGCCATCGAGGCACAAACCGCCAAAGGTCGGGTCACCGAACTCGAAGACGAGCTATCCGCCGCACGCGAAAGCCTGCGCCGGGTCATCAAAGCCCAAAACCGCGCACCATGACGCACACCTTTGCAGCGACTCCCGCACGCAGCCGCACACTCCCACGTGCCTCACGTGCCCCACACTTGAAAACACCTCTGACCAGCACATTTTCAGAAAAAATACAGATAACCCTGGGAACACGGTTGATCAACCGGGACGTGCCGCAAGAAGTCGTACGGGTGTTACTCGATCACTCCAGCGGTGAGATGACAGCTCACTACGCCCGCCTTCACGACACCACCGTCCGCCGGCACTGGGAGTCCGCCCGCAAGGTCGATGCCAGGGGCCAAACCGTTGCGATCGACCCCGACGGCCCACTGGCCGAAGCGAACTGGGCCAAGCAACGGCTCGGGCGCGTGACCCAAGCATTGCCCAACGGCTTCTGCGGGCTGCCAGTTCAAAAGACCTGCCCGCATGCCAATGCTTGTCTGACATGTCCGATGTTCGTGACTACGCCCGAGTTCCTGCCGCAACACCACGAACACCGTCAGCAAGTCCTGCAGATCATCTCCGCTGCCGAGGCGCGCGGTCAGTTACGCCTCGTCGAGATGAACCAACAAGTCCTGGGAAACCTCGACACCATCATCACCACACTCGAAACCGACTCCGGTTCAGAGGAATTGGATTCTGCTGATGCGGGCTGACAACACCCGGCACCTCATCGTCGCCGCCCGACAACGCCACGAACTCACCCGAGCCAAGGCGATCCAGGCATTGAGGACCCTCGACGCCGAAGGGCGCCCGGTCACCTTCGAGGCCGTGGCTCAAGCAGCGGCGGTGTCTCGGTCCTGGCTCTACGCGCAATCCGACGTCCGAGCTGAGATCGAACGGCTTCGCGCTGCCCACCGTCGAGCACCCGCGACACCGGTCCCCGCGCGGCAACGAACCTCGGACGCCTCACTGCTACGCAGGCTCGAAGCCGCCAACCAGCGCAACCGGAAATTGGCCGAGGAGAACCGCACGCTCCGAGACCAACTCGCCCGAGCACTCGGCCAGCAGCGCACCGCATCCGAAACCACGTCAACCCGCACCCCCCGGAAACGTCTCAGCTCGATAACGATCGGTCCCTGCTGAAAGGCCTCCCCCATGACCCCACCTCAAACGTCGACGACAACGTCCACAACGAAACACCGCAGGTCAAAGCCCCGAATAGGCCAGCGGCTCAAGATAATTCAACACCAAGTCGGACATTCCTATGCGAGCACCACGTCGATCTATAGCCACGTCTGACGAGTACCGCAACCGTTTGCTCCGTGAAGCGCTCACCAAACGCGGCATTGCCGTCGGGGAGGATCAACCGTGATCAAGAAGATGGGTTATCAGTGGCGGCTGCGGGCGCTGATGGCGCAACGGGAGCTGTACCAGACGACTGATCTGGTTCCGCTGTTGGCCGAACGTGGCGTGGTCCTGTCGCGAGAGCAAGTGTTTCGCCTGGTCACTGCGCCTCCCCAACGGCTCTCAATGGACGTGCTGGCAGCGTTGTGCGACATCTTGGAATGCTCGCCCAACGACCTGATCGAAATCGAAGCCGTCAATCAATCGGTGAAGAAGGCGGCCGGGGACTCACCGCGGGAGGTGCCGAAGGTGCGGCGCACGACTGTGCGTCGACCTGACCGCAGCTCATGAGAGGATCGGCGAACTTCAGGCCCGACGCGTGGGATCGAGTCCGCGCTCACGTAGTCCGCGCTCTTGGCGACCTATCGCTTGCAGATGCCGACCGCCTCCTGAAAGCTGCTCGTGTCGACCGGCCGAAAACGCTCAATCAGGTCGACGCGTACCTGGCCGCTCATGGCGACGGAGTGCTCAACCCGGACGCGTCCTGCCCGCGGGGGCTTATGCGCTTGACGCACGTACTGGTGGCTGATGGCCACGCGTCGGTGAAGCCGCCGGCCTGTACGAATTGTCAACAGCGCGTGTCTCTGACCGCGATCGGTCCGACCGGCCGCATTTGTGGTCGCTGCAGAGATCTCGATCGATCGTTCACGTGCGCGCGATGCGCAAAGACCTCTGTCAGCAGACGCGTCAATCTTCCCGACGGACCCGTGTGCACGAACTGTTACAGCCGCGACCCGTTGTCGCGCAAGGAATGTAGCATCTGCGGACGCCTCCGTCCCCGGGCACGTCGACTCGTCGACGGCGGCGTGCTGTGTCCCACGTGCGCGCCACCGCGCCTATACACCTGCTCGGGATGCGGACAACGGCGCCGCGCCCCGTACGTGGCATCGGAAGGACGCATCTGCACGAACTGCTACGCCAAAGCCAGCACCGTGTGGGTATGCGGATTATGCGGAGCCACCCGGCGCCGCCAAAGCAGCAGCGTCCTCGGCCCGCACTTGTGCGGCACCTGCCGCGCCATCACAACGAGGACCTATTCCGGGATACGTTCACCACACTCGAAATCCACCTGCGCGTTCTGCCGACAACGGCGCGTTGTAGCCCGCCATTGGCCAGCGGGGCCTGTCTGCACACCGTGCGTGCGCAAGGCGAAGATGTACCCGTCACCATGCGCGGCGTGCGGCCAGCAGGCGGTGCTGATCGGATTTGACCCCGACGAGCGCCAAATCTGCGGGCCATGTTCTGGCTCCACGCTCGACTACCGCTGCGCCAATTGCGGTCAACCGGGTATTCGCGCGCATAATCGATGTAGCCGCTGCCACACCGCCGAATTACTGCACAACGCCTTAGCCGGGCCGGATGGCCAGATACCGGCGCAACTGAAGCCACTGGCGGACGCTCTTGCCAACGCCAATGATCCACGCAGCGTCGCCGTCTGGCTCGGCAAGAGCGCCGCCGCGGAGCTCCTCATGAATCTGGCGCGCACCGGACAGACCATCACTCACCACGCACTCGATCAGCTCCCACCCGGTGGGCATGTCAACTACGTACGTGAAATCCTCGTTCGCACAGCAGTATTGACGCCGCGTAACGAATACCTCGAACGTATCGAGCCATGGGTGGATCGCCACCTAGCCAACTATCCCGCCGAACACGCACGGCTGGTCCGCAGCTACACCATCTGGTACCTCCTGCACCGAGCCCGCCGAGCCAAACAACCACTAAGCAATCCCGGGTGTCAACGGCGGGGTGGCTTCTAGTCAACGTCGCAACAGTTGATGGTCTGGTGAGGTTAGCAGCGCGGTGAAAAGTTCGGCGGGACTGCGGTCTTCGAGGGTGTGGCGGGGGCGGTTATTGATCTCGTATTCGACAGCGCGCAGATGGTCGGGTGTGTAGGTGCTTAGGCTGGTGCCCTTGGGGAAATATTGGCGTAGCAGCCCGTTCGCGTTCTCGTTGCTGCCGCGCTGCCACGGCGAGCGGGAGTCGCAAAAGTAGACCGGCACGCCGAGGTCTGCGGTGATGTCGGTGTGTCGGGCCATTTCGATGCCCTGATCCCAGGTGATCGATCGGATCAAGTTCGATGGCAGGCCACCCATGGTCGTGGCGATCGCGATACGCAGGGAGTCGGCGTCACGGGTGGGAAGGTGCATCAGCCGAATCAGGCGGGTCTGGCGCTCGACCAGGGTCCCGATCGCCGAGCGCTGGTTCTTGCCGACGATGAGGTCACCTTCCCAATGCCCCGGCTGGCTGCGGTCGGCGGGAGCGAATGGCCGCTGATGGATCGACAACATCGGCTGGGCGAACCTCGGACGCCGCCGACCCGGCCGCTGGTGCGCGCGGCGATGGGTCCTGCCAGTGCGCAACGGACCCCGGTGTGACGACCTGACCTGTGGCGGCCGTATCAAGCGCGAATGGGGTTGGTACACAGCCCGGTAGATGCTTTCGTGGCACAACCACATCAATCGGTCCTCGGGGTATTCGCGCCGCAAGTGTCGGGCGATCTGCTGCGGGCTCCACCGTTGAGCGAGGAGCTCGGCGATCAGGTCACACAGGGCGGGATTCTTGTCGACCCGCCGCTGGTGACGACGCGCTCTGCGCTGAACCGCCCAGCGGTGGGCTTCAAACGGCCGGTACTGGCCGTCGCGGCGGCTGTTGCGGCGCAACTCCCTCGATACGGTCGATGGTGCCCGGCCAAGCGTGGTGGCGATCTGCCGAACACCCATGCCCGTGCGGCGCAGATCGGCGATGCCGATCCGCTCCTCTTCGGATAGATAGCGATCGCTGATCTGGCGCACAGCCAAACGATCGAGTGCGGGCACGAATCCCACGGCCTCGCCACGCCGATAGGTTTTGTACCCCCTTGCCCAATTGTTTGCTGCGGTACGGGACACACCGACTTCACGACCCGCCGCCAAGATGGACCAGCCCCGGGCGCGCAGCTCCGTAAATCGCTCACGCTTGGCGGACTGTGGCCGTCGGCCCGGGCCTTTTTTCACGCGACGCGACGATGACAACACAACCTCCAGAACCTAGAGAAGTGTTGCGACCGCCCCTAGAAACCACCCGGGGACACGGGGTCAGTTTTCAGACGACGCCGACACCGGGGCAGCACGCATTCGCCGCCAGGTGTGCGTCGCACTGGAATTCCTCGCTTGGCTCGAGACCCGGGGACGCACCCTCGCCACCATGGACCAAGCAGACATCGACAACTGGTTGGCCCACGGCACCTGGCGACACCGAGAGATCCGGCCCTTCCTGCACTGGACAACTCAGCGTCGCATCACCCACGGCGCCTCCGCGCCGGCCAACCGACCCAGCCCGCCCTCGGTGTTCATCGACGAAGCCACGCACCTCGAGCAACTCCGCCGATGCCTCAACGACAACACCATTGACATCGATGTGCGCGCCAGTGGTGCGCTCATCCTGCTGTACGGAATCACCACCATGCGAGTACTCGGGTTACGACAGAACCAGATACACACCCAGGACGGCCACACCTACCTCACCCTGCGCGACCACGAAATGGTGCTGCCTCCTAAGCTCGCCCAACTGCTCGCACAACTGCCGCGTCCAACCCGGCGCTCGACCCTGCCCGAACCCTCAACACCGGACCGGCTCCTGTTTCCCGGACGAACACCAGACCGCCCAGTCAACTCGGGCGTGTTCGGCAAGCGACTCAAACATAGCGGCCTGACAATCCGAGGCGGTCGCAACACCGGCCTCATCACAATGGCAGCCGAGTTACCGGGCGCAGTTCTGGCCGACCTACTCGCCATCGATATCGTCACCGCGACCCGCTGGGCGGCATATGCCAAACGCGACTGGAATCAGTATCTTGCCACCCGAAAAGCGGGCTCTACCTAGCAATTGCGCCTGCCCCACTAGGGTTAGCCCATTTGATCACCGGTGGTTGCCGTTACAAATATGGTGTGGGGTTTCGGGTTACCGGCCGGGTCCTCCGGGCTGTGGACGTGGCAACGGCCGCGGCTGCCGCCGAGCGCGATGGTTCATCGCGGTCCGCGATTAGTCGAATCCGGCTAGTGTGATTCTCAAGGCTTGTTCCAGTTGAATGTGGAGCGGTGGACTCGTTTTGGTGTCCGTGCTAAGCCAGCGCCGAAGTATGAATTGTGCAGTGGCCAAACCCGTGTGGACCAGCAGCGAGGGGCGGATGTCGGTCACCGCGTCGACGTCCATATGCGTAGCGACCAGTTCGATGAGCCGGTGGTTATCGTTCTCGCTGATCAGCGCCGATTCGCCCAGTAGGTGGGGGGCGGTCCGGATGGCTTCTCGCCAGTATTGCAGATTCTGATTTGCTTTGTCCCAAGCGGTTTCGATAAGCAGACGCATCAGAGTTTCGGTTGCTGATGCATCGGACGGCTGGGCGCGGTAGGACGCAACGATTTCGGCGACCGTTTGCCGGACGGGTGCGACAAGCAGGTCTTCCTTGGTGGGTGCGTAGCGGAAGTAGGTACTGATCGAGATTCCGGCCGCGGCCGCGATGTCCTCGGTTGTCACGGCAGCGAATCCGCGTTCGGCGAAAAGCTGGTGTGCGGTGTTCTGGATCTCGGAGATCAACTCGGCGCGGCGTCGGTCCCGTAACGAGCGGATGTTTGCTGACGGCATGCCATCACCTTCGTCAATGTGACATTCCAACTGCATTATGAGCTATGGTACGAACAGTAGCGTAGCGAAACCGAAAGTACTGGGGGTATTTCCTTGCCGGTGTCGCAGCGTCGGGTGCCGTGGGTTGCGTGGGGAATTGCGGCTACCCGCATGAGTATTCGCTGCCGAGTGCGCCCGGAAGCGTCCGCCGATCGGGTCCGCGTTTCGCACCGCGGTCTGGACGGCACAGCTTCAGTACCCACTCATGGCTGTGTCACCAGTACGCTCGTGCTAGCCCCGTTTACCGCACTCGCGGCTCTTGCAGTTGCGCTTGCGGCTGCACGCATATCCAACGGTCTGCAAAGACATCGTCTTCCCCGAAGGGGGATTTGAGGAATGTCATCCCGCCACCTCCTCGTCGAAAGGTCTATCCCCGAAGTGAAGTCGTAGTGTCGGTTGACGTACCGTTCCGCGCGGCGCCAGATTCCGAGACCGGTACCGGGGGCAGCACCGCAATCCTCGATGCTGCCCGAGCGGTCGCAACGGCGGGCGGTTTCAAGGCCGTGCGTCTCAAGACGGTGGCCAAGCAAGCTGGCATCACTGTCGGGTCACTGTATGACCATTTCGCGTCGAAGACCGACCTGCTGGTGACGCTGCTCGCCCGTGAGTTCGAGCGGGTGAATCAGGAACGCGACTGGAGCACGTGCGCCGCTTCCCCGAGTGACCGACTGGGATCGTTGACAGCGCGGCTCCACGACGAGTGGCAGCAAAACCTGCAGCTCACCGAGGCCGTGGTTCGGGCATTCGTTATGGCGGGCACAGACGAAGCCTTGACAGTGCAACACGCCGCCGACGTCGTCGAAAGCATGCTGGCGCGCACGGTTGGTGGGCCGACGCAGGGAGCTTGCGAGCGACAGATCGCCGGAGTCATCGCAGATATCTGGCTGGCCAATCTAATGGCTTTCGTCGTCGGACGGGCGACAGCAGCGGAGGCGCGCGAGCGCATTGATCGAGGTCTGCAGCGCATTCTTGCTGCGTGGAACGCGAGCAAGAGCGCATAGCAATACTAATAGTATCGGTGCGCTACTAGCGGTAGCATAGGTAGGCGACTCGCTGGTGCGTCGAAGGGAGTGGTTATGTACACGCAATGGATCGAGCAGTGCACCGTGCAACGAGTCTCGCTGCACGAAGGGCTGGTAGTCGACCTGGACGATCACAACCAGCTGGTGATTTCCCGACCGATGCGGCTGACCCTCCCTCCGGCAGCAGGCTGGCCTGAGGAAGAAGTGTTGATCGACCCTATCAATCTTTCGGCCGAGGAGCGGCCACTGTTGGACCTGGCCGGAGCGATCTGCACGCGTGCCTGGTGCGACGACGACGGTGCGCTGCATCTGTGTTTCTCCCGCGGCCACCGCATCGATGTCGACCCGGATGCGGCGGCGACTTCGTGGGAGCTCTATGGCAAGTGCCACGGCTACATGGCGTGTCTGCCGCGGGGTCGAGTCCGGGTGATTCGGCACGACCTTCCTGTTGACGAGAATGACTTAGACGCAACACAATCAGTGGCCATGGCGCATCAGTAGCCGCGCGCCTGGCGACAGGACGGCACAAGCGCCGAAGGCGTGCGAACGATAGATCGAGCCATCTCGATGGGTGTCCGACGTGTCAGCCGGGGCGGGTGCAGGTTCGCTGGATGCTTACGTCGGGGTCCTTGTGGTGCGGTCGAGGAAGTCGGTGACCGCGGCGGTAAACGCGTCGTTGTTGTCGCCGGCAACCATGTGACCGGTGCCGGTGACGTCCGTCGTTTCGGCGTGCGGGACGAGCTGGAGGAATTCGTTGACGGTTTCCTGGGAGACTACGTCTGACAGTGCGCCGCGTACTAACAGCGTTGGGGCCGTGATTCGACGTGCTCCTTCGGCGAGAAATCCGCTGATGGCGTCGAACTCCTCGCTGCCTGTCATGAGATTGCCTTGCAGGACATCGAAGTTGGAGCTGATGAACGCTGGGTCCCAGCGCCAGATCCATCGTCCGTCGCTACGTTGCCGCAGGACCTTGTGCAGGCCGTCGAGATTTTCGGGTCGCGCGCGCCGGGGGTTGTATTCGGCGATGATGTCGGCGGCGTCATTGAGTGAGCCGAATCCGTCGGGGTGGGCGGCCATGAATGACACGACGCGACGGGCTCCATGAAATTCGATCCGCGGGGTGATGTCGACCAGGACAACGGCTGCCCAGAGGTCGGGTGGGGCCAGCAGATGGGTAGCGAGGATGATCAGCCCACCCAGCGACGCGCCGACGACGGCGGGGGGACTGTCGGCGCTGACGTGTCCTCGTACCGAGATCAGATCGGATACGAACCGTTCGACGTCGTATTGTCCGATCGGGTCCCAGTCGCTGTCGCCGTGACCTCGTGTGTCGTAGGCGACGACGGTGTAGCCGTGGGAATGGAGTCGACGAGCGGTGGTGGCCCACGCGTGACGGTTCTGACCGCCGCCATGGAGGAGCAGCACGACGGGGCGAGTCGCGGCGTGCCGGTAGCAGTCGGCCACGAGAGTGATCCCGTCGCTGGTGCGGATGCGCTCCTGGCTAATTGTCATGTGGTCCGATGTGGTCGGCCGTTGTGAGTCAGGGGTTTCCGTTGCGGCCACCAGCTCGCTTCGCGCAGCAGTGTGGCGATCGCGGGAACCGTGAGCGTGCGAACGACGAAGGTATCCAGAAGTAGGCCGCAGCCAATGATGAACCCGGCTTGGATCATGATCGCGATGGAGCCGACGATCAGGCCGAACATGCTGGCGGCGAAGATGAGCCCGGCCGAAGTGATGACTGAGCCGGTATTTGCGACGGTTCGCAGGACGCCGACGCGAATGTTGTGGGTCGATTCTTCGCGTAGTCGCGAGATGAGCAGCATGTTGTAGTCGGCGCCGACGGCCACCAGGATTATGAACGCTAGAAGCGGTACGGGCCAGGCGATTTCCTTGCCGAGGCCATATTGAAAGACGAGGGTTCCCAGTCCGAGCGCGGCGCCGTAGTTGAGCACGACGGTACCCAACAGGTAGAGCGGGGCGACCAGGGCGCGCAGCAATACGACCAAGATGAGGCCGACGATGACGAGGGTCGCAAAGGCCAGCTGATGAAAGTCGGCGGAAAGCAGGCGTTGGATGTCGGAGTTGACGGCGGGGAATCCGGCCATCGACACCGTGGCGTTGGCCAGCGAGGTGTTGGGTCGTGCGGCATCGGCGATCTCGGTGATTTTGTGGGCGAGGTTCATCGCGTCGCTGCTGTAGGGGTCGTAACTGGATTCGATGGCGAAACGCGCGGTTTTGCCGTCGGGCGACAGGAAATGCTTTGCGACGTCGGCGAATTGGCGGTTCTCGAAGGCATTGGTGGGAAGGTAGAAGCCGCTGGCGTTGTCTGAGCCGGCGGTGGTTCGTGCGGAATTCTGCAGTTGGGTGGCGATTTGGCTCATGCCCGACAGCATTTCGATGTTGCTGTCGGCCAGGGTGTGCACGCCGGTGGCGAGGGCCTGTGCGCCGGAGGCGAGTTGGCTGATGCCGCTTTGGAGGCGGCGGATGTTGCCGGCCAGGTCGGCAGGGTCGCCGAGTGCTCCGAAAGCCTTGTCCAGCGACGTGATTGCGTTTTGGACGTCGGCCACGGTGCCGGCCGCGGTGTCGCTGCCGGGCTGGTAAAGGTCGCCGAGGTTGGCGAGCTGGTTGAAGAAGCCGGTATGGCGCAGGGTCACCAGGATCTGCACCTGGTCGCGGAGTTGGGCGCATTCCGGTGTGGTCGCACACCATGGGGAGGTGTTGAGCGCACCGACGAGCGGGTCGATGGCGGCGATTGCGTTTTGGGCTTGGTCGGCTTGCTGGCGCAGTCCCGGACCGGTTCGGATGGCTTGGTCGACGGCCGGGGCGGTAGCCGAAAGCTGCTGTAGCAGCGGACGGAACCGCTGGACTTGGGATCCACTGGATTGGGCCTGGGTGAGGATCCCGGTCAACGGTGTCAACGCGGTGCGCAAGGTGGTGTCCAGTTGCGCGAGACCGCCGGCGAGTTGGTCGGCGCCGTGGGTGAGTTTGGCCAGGTCATCCTTATGGGCGTCTCCCTTGGCGACCGCGCCGGCCATCTTGTTACCGATCTGGCCGTTTTGCCACGACAGTTGAGCCTGGTCCAGGCGTGCGCCCGTGGGCCGGGTGACACCGGAGACCTTGGTGACACCAGGCAGTTGCGAGACCCGAGACGCCATTTCATCCAGGTCGGCCAGGGCCTTGCTGGTGCGCATATCAGTGGGCGATTCAACCAGCATGAATTCGGTGATGATGACGTCCTTGCGAAAGTGGCGGTCCAGCAGGTGATACCCCTCATTGCTGGCGGTGGTCGCCGGCTGTCCTTGGCGATCGTCGTAGCTGATGTGCATAGTCAGCGCGACGGCCGCCAGGCCTAGCACCAGGGCCAGACTGGCGACCAGCAGTGGAACGGGTCGACGCACCACGGCCACGGCGATCCAGTTCCAGTAGCGGCGTGTGCGGTCGGCCTTGGGTTCACCGATGCCGCGTTTGGCCGCCAGCGCCAACACCGGGGGAAATAAAGTCACCGTGGCCGCAAATCCGACAAAGACGGCGATTGCGCACGCGGGACCCAACGCGGCGAACACGCTCAACTTCGCGAACACCATGGCCAGAAACGCAAACGCCACGGTGGCGGCCGAAGCCAAAATCACGCGCCCGATGGTGGCGGTCGCGTTGATCACCGACAGATCCGGCGGGACGTTTTGGCGTCGCTGCTCGTGATATCGACTGATCAAGAACACCGAATAATCGGTGCCGGCACCCAGCAAGATCACCGTCATGAAGGCGATGGTGAACTGCGACACCGGCATGCCCGATTCGCCCAACGCTGATAGCACTCCGCGCCCCACCGCCAGGCTCACGCCGATGACCAGCAGCGGCAGCAAGGCGGTAAACACCGACCGATACACGACCAGCAAAATCATCGCGATCAGGCCTGCTGTCGCGACCGAGATGACAACCAAATCCTCTTCGGCCGAAGCGATTTGATCGCGGAAGGTGGCCGGGGGCCCGGTGACGCGAACATCGGTGGGTGAGCCGCTAAATGCCTGGGCGGCGATCGTGCGGACCGCCTGGACCGATTCGGCAGCTTTGAGATCGCCCAGCGTTCCGGCCACTCCCACCGGCACATACCAGGCTTTGCCGTCTTGGCTGACTGCCTGGCTTGCGGTGACTGGGTCGGCCAACAAGTCTTGAACCAAGCGCACATGCTCCGAATCGGCACGCAACCGGGAAATCATCGCGTTGTAGCGTCCGCGCACCGGCGCAGTCAGGCCCGCCGGATCCTCCATCGCGACAAATATCGTCGTCTTGGATCCCTGCTCGCCGAAGGCCGCGCCCATGCGGTCTACCGTCTGAAGCGATGGCGCATCGCGCGGTATGAGATTCACTGACTGCTGTCTAACAACGGTTTCCAGCTGCGGGAACAGCACCGCCAGGGCAGCGGCGCTCACCACCCACATGCCGATGATCAGCACCTTATGTCGGATACTGAAACCCGCCAAGCGCGCTAGCCGATCGCTGTACGCGCCCTCACCGGCCGCAACCTTTTGAAGTCGCTCCCGAACAGGGCGACTCAAGGTCGCCACGCCCGAAGAGACCCACCCGTTGTCTGCCATCCCCCGCCCCGCTACTTCGAAAGAAATCAACGGTATCGCAACAGTACTACCAGTACCCTTCTACCTGCCCGGCGAAACCGCCACCGGTGTCCGAAGCTCTCTGATCGCCGCCGCGCAACCAGCCGCTTCAGGCGGTGACCAACGCGCCGTCGACGGTCCAGCATGTCCGGTACAGCGACACGTGATCCCTTTGCGCACAGGCGGTTTGACAATGACGATGCACCGACTCCGAAACAGTGACCGCTTCATGAACGGCGCAGGCGAAATCCCAGCCGGGAGATCAACCTGATCGGCTCGTCGCGCACGTGGTCATACATTTCCCGGTTCATCAACTCGTCGTCCAAGTAGGAGCAGGAGCGAGGAGGGTAGTGACGGGGACGAACGCGGCCGCGGTCATCAACCGGCGGCTGTCGGTGTAGGCGCCGAGTGATACCGCGGCGGACCAGCCTGAAATCGCGAACCCCCCGCGCCCACACATGCGTCTTGGTTAGCCCAAGCGGCACATTCATCGCCGACCAGCCCCGCCCGTCTGTGCGATTCCCCCTCGCGCCCGCCGGCAGAGTTCGTTCGTCCGCCACACGAACCGGCCTGTGGTGGCCGCGCCCTGGAGCTGCTCAACCAGGGATCGTCCGACCCGCTGCCCGATCATGCGTCCTCCTTCGCCCCACAGACCCTTACAGACAAGTGTACTAGTGGTATCGCTACGCTACTAGTAGTAGCGTAGCCGTCTAGGGGTCGAATCAATCGACCGATGCAGCCGCGATTCGGTGCCGGCCAGCTACGCGCGAGGTTTACGGTGACTACATGGAGCGCGACACCCTGGAATTCCCGGTCGACGACGATGATGACGTCGACCCGCGCCTGTTGCGCTCACGAACCCGGCTATTGGATGCGGCCACCAAACTCCTGAGCGCCGGCGGCATCGAAGCCGTCACCATCGACGCGGTCACCAAAGCCTCCAAAGTCGCGCGCACGACCCTGTATCGCCACTTCAGCAGCTCCACTCAACTGCTTGCCGCCACATTTGAAAGGCTGCTGCCGCAGGTCCACCCTGCACCGGAGACGGGATCGTTGCGCGACCAACTCATCGAACTGTTGAGCCGACAGGCCACGCTGTTCCAGGAGGCACCGCTGCACGTCACCACCCTGGCCTGGGTCGCGCTTGGCCGCACACCAAACGGCACCCAGGAAACCCACGACCGGCACGCGCTGCGCACACGGATCATCGACCAGTATCGCCAGCCATTCGATGCCCTGTTGCAAAGCCCCGAAGCCCGCGCCGACCTCGACGATTTCGACCCGGAGCTCATCCTGTGTCAACTCGTCGGGCCAGTGGCGTTTGCCCGACTCACCGGGCTGCGTGCCATCGATCGTCAAGACTGTGAGCGCATCGTCGATGACTTCCTCGCCGCGCACCGCCGCAAGGCCGATGAGCCCGCATCGTAGGCCACCGTCCGCAAACCCCTCTTTCCGCAGCAGCCGCTTCACTTTGTCCTCCAAGACTTCAGGACTTCATGCTCGACGGTGAGGTCTTTGATGGTTTCCCTATAGACCAACCGCCAACGTCACCAGCGGGCCTATGTCGCCGAAGTGTCTTCTGGTGCGGGGTGCAGCAGAAAGTAGGCGTTTAGGTCGATGTCTTAGCGACCGTCGGGCGCTATTGAGAAAGGTGCGTTGGATGTTGCAAAACTCGCGTGTTCTCCGAGGCTGTCTACGGCGATCCGCTTTGGTTCGCGTGGCCCAATCACATGAAGATCTTCTGCAACAACAAGGGCGTTGTCGCCAAGTCCACCCACGTGTGCAACAACTACCTTCCCCGGGGAAATGTCGGTCTGGAACTGGAGCTAACCCCGCCCTAGTCCCGCCGCGGTCGGGACTGCATGCACCTCAGCAATGCCTTAGTAGTGCGGTGAGGCCGCCGGGAACCGGTCGGTGGTCGCCGACTGCGGGTCATCTTGCCGGGGCAGCAGGTAGGCGCGAACCGCCGAACGTGGCCCGTAGGGCCGAAGTAGCTGGCTGGCCGGGCGAGTGCGTACCTGCTGCGGCCACCAGAACCAGCGCCCCAGCAGCGCGGCGACGGACGGCATCATGAATGAGCGCACGATCAGGGTGTCGAACAGCAGACCCAGGCCGATGGTGGTGCCGACCTGCCCGACGACTTTCAAATCGCTGAATATGAACGAGGCCATGGTGGCGGCGAAGACCAGGCCCGCAGACGTCACCACCGCACCGGTGCCGGCCATCGAGCGGATGATTCCGGTTTTCAAACCGGCACCGATTTCTTCTTTGAAACGGGACACCAGCAGCAGGTTGTAGTCGGATCCGACGGCCAGCATCAAGATGATGGACATCGCCAGCACCATCCAGTGCAGTTTGAAGCCGATGATGTCCTGCCACACCAGCACGGACAGTCCGAACGAGGCGCCCAACGAGATCAGCACCGTGCCCACGATGGTGACCGCGGCGACCAGGCTTCGGGTGATGATCAGCATGATGATCAAAATCAGGCTGGCCGCAGCTATTGCCGCGATCATCAGGTCGTATTTGGAGCCGTCGCGCATGTCCTTGTAGACCGCGGCGGTGCCGGCAAGGTAGATCTTGGCGCCCTCCAGCGGAGTTCCCTTGATGGCTTCCTTGGCTGCGTTCTTGATCGGCTCGACGTGCGAAATGCCTTCCGGGGTCGCGGGATCCCCTTCATGGGAGATGATGAAGCGGGCCGCGTGCCCGTCCGGCGACAGGAACATCTTCAGACCGCGCTTGAAGTCGGGGTTGTCGAAGACTTCCGGCGGGATGTAGAACGAGTCGTCGTTCTTGGCGGCGTCGAAGGCCTGGCCCATGGCGGTCGAGTTTTGGCTCATCACGTCCATCTGGTCATACAGCGACGACATCGAGCTGTGCATGGTCAGCATCATTTGCTTCATGGTCGTCATGGTGGCGATCATGGGCGGCATCTGCGCCAGCATCTGCGGCATCAAGGCGTCCAGCTGAGATATGTCGCCGGCAAGATAGGTGAATTTTTCGGTGATCTGATCCAGACCGTCGAGCGCGTCGAAGAGGGATCGCAGCGACCAGCAGCCCGGGATGTCGAAGCAGTGCTTTTCCCAGTAGAAGTAGCTGCGAATCGGCCGGAAGAAATCATCGAAGTTGGCGATGTTGTCGCGCAATGTGTTTGTGACATCCAACATTTCATGCGTGAGGCCGTCCATGTGGTGGGTGACCGCGGCCATCTGCGAGGTGATGTTGTACATGCGCTGCATGGTGTCGATGGACTGTTGCATCGCGTCGGCCTGCTTGAGCATGTCGTCCATGCGCTGGTGCATGTACTGCTGGTTTTCGACCTGCGTGGTGTTTTGCATGCTGATCTGGAACGGGATTGAGGTGTGCTCGATCGGCGTTCCCAGCGGCCGGGTGATCGCCTGGACGCGCGCGACACCCGGGATGTGGAAGACCCCCCTGGCGATCCGGTCCAACACCAGCATGCCCGCCGGGTTGCGCATGTCGTGATCGGTCTCGATCATCAACAATTCCGGATTCATCCGGGACGCGGGGAAATGCCGTTCGGCGGCGGCGTAGCCGATATTCGCGGGGACGCTCGGGGGTAAATACAGCCGGTTGTCGTAATTGGTTTGATAACCGGGTAGGGCGAGTAGACCGATGAGGGCGATCGCGACTGACACCGCGAGAATTGGCCCGGGCCAGCGCACGATCGCGGTGCCCACCCGTCGCCATCCCCGGGTCCGCATCTTGCGCTTAGGATCGAACAGCTTGAAGAAACTGCCGACGGTCAGGACCGCCGGACCCAAGGTCAGCGCGGCAGCAACGGCGACCAGCATCCCGACCGCACAAGGGATACCCATAGTCTGGAAATACGGAAGCCGGGTAAAGCTCAGGCAATACATCGCACCGGCAATAGTCAGGCCAGAGCCAAGGACGACGTGCGCGGTTCCGTGGAACATGGTGTAGAAGGCTTTTTCGCGGTCCTCGCCTAGGCCGCGCGCCTCTTGATATCGGCCGAGAATAAAGATCGCATAGTCTGTCCCAGCGGCGATGGCCAACAGCACCAAAATATTAACCGCGAAGGTCGACAATCCCATGATGTTGTTGTAGGCCAGGAAAGCGACAACCCCCCGAGCCGCCATCACCTCGATCACCACCATGAACAACGTGCTGAACACGGTGATAATCGAGCGGTATACCCACAGCAACATCACGATGATCACCACGAAGGTGATGATCGTGACCTTCTGGAGGCTCTTTTGTCCGGCCGAGTGCTGATCGGCGATCAACGCCCCAGCGCCGGTCACATAGGCCTTGACCCCCGACGGCGCAGGCACGCTGTCCACGATCTTGCGGACCGCCGCGACAGACTCGCTGGCCAGGCTCTCGCCCTGGTTACCAGCAAGATACGCCTGCACATAGGCGGCCTTGCCGTCGGAGCTTTGCGAACCGGCGGCCGTCAGCGGATCCCCCCAGAAGTCCTGGACGTGCTGGACGTGTTTCGTGTCAGCCTCGAGTTTGCGGACGATCTGGTCGTAGAAATGGTGGGCCTCATCGCCCAGCGGCTTGTCACCTTCCAGCACGATCATGACCGCACTGTCACTGTTGAATTCGTTGAATACTTTGCCGATGTGCTTCATCGCTTGCATCGACGGCGCGTCCTTGGGGCTCATCGACACGGTGTGTTCTTCGGCGACCGCGTCCAGCGATGGAACCAAGACGCTGAGGACGACGACAAGCCCCACCCAGGCAAAGACGACGGGCACCGCGAGTTTGTGGACCGTTCGCGCGAAAACCGGCATATGCGGCAGCCCTGCGGCCCGGTCATCGGTCATGCGGACTTCACTATGCAGAACGTTTGCGCATTCATACCCTGACTCGACCTTTCGTCCTTGACCACCTCGTCCACGATGATCCGGCAGCCGATTTGGTTGCTGTCGCCCTGCGCGACGATGTTGACGCTCACCGAGGGCAGCGTCGAGGTAACCGAGAGCGTCCAGGGCAAAGGCACGTTGCTAGCTTTCTGGGGCTGGGCATTGATGTCCAAGTAGTTGATGTTGGCCACCGTCCCCGGGGGACCATAAACCTGGTAAACCACGCGCTTGGGATTGAACGGCTTGATCTCATCGGCGATGCCGCTGGTCATCGTCTGATCGTCGTGGACGCCGAAAAAGGTGCGAAGCCGCAGTACGCAGAAGCCCGCTACCGCCACCACCGCCACGATGACCAGGACGATCCACATTTTCTTCATCGCAGCGCCAACGTGAATCCTCCCCAGCCAACCATCTCCCGCTAGTTGGGCGCCCCACCGCCCATTCGACTGGATCGATCGCAACTTAGCGTTTGGCGCAAAGCCATTGCCGGCGGAAGGCTGCGCGGTCTCGCCTGGTTCCCGGCCATCGACAAGGTTGGCATCGTTTTCACCGGTTGCAGTTCGCCAAGCCACTGCGTCCTGGTCTCCTTTTCTGTTCATGAGGTTTCAGAGATGAGGCCGATGCACCTGGCGGTCAGCAGGCGGGTCAAGGCGGACGCGAAGCCCAGATTCCACTCGGGCGGAACGACTTGCGCGCCCTTTGCGTAGACATCGGTGAGCCGCTCTGGCGGGTTGGCGTCTGCCAGAGGGTGGCCACCAGCGAGTAGGCGGCCAACAGCATATCCAGTGATCCCGAACGGCCGAGCGCAGGCAACGAGCTCTCAATTGCGTCGGCGGGGATAGCGTCGCGGCGGTCCTGATCCGCTTGACCTCGACAACCCGTTCGTCGTCCACCTCGTGCTGCGACCGGCGTCTTGGTCCGCGCCGCACTTGAAGCCCTGCGCTACTGGCTGCTCTATGTTCCACGACCTGCGCGATGGGCGGATTATGCGCTGTTCTTTTCCGGCGCGGTGGTGAGATGACGGATAAACATCGCCACCTCCTCAACCGCGCGAAGCGCATCTGGGTTGACGTCGAAACCGAGCTGGAACATGTGCATCGCCTTGTGCCACTGCTGCACCCACACTGGTACGCCGTGAGCCCGCAGCCGGTCGGCCAGCGTGAGGGTGTCATTGAGCAGCATCTCGTGGGTGCCAACCTGGAGCAAAAATGGGCCAAGGCCATGCAGATCGGCCTCCGACGGCATCACTGGCGCCGCCCGGGTGCCGTTGACAGTACCGAAGACGTCATAGAGGAACTTCACCGTCATGAACGGAAACATCACGTCGCGATGGTCTTTGAGGGCCCGGTACTTCAGCCCCATATCCGACGACGTCAGCGGTGACATCAGCGCCTGACCCGCAGGCACCGGCAGCCCGCTGTCGCGGGCGGCCAGTGCGGTACCGGCAGCCACCATGCCACCGGCCGAATCTCCTGCTAGCACAATGCGATCCGCTGAAAAGCCGAGCGACATAACGTAGCGGTAGGCGTCGAGCCCGTCGGACACGGCATCCTCAAGGCGGGCCTGCGGGGCCAGCCGGTAACCGACATTGAATACCCGCGCGCCGGTCTCTTGGGAGAGCTTACCGACAAACCGCCGATGCGAATTGAGACCCAAAGTCACCAGCGCCGAGCCGTGGAAGTAGACGATAACCCGGTCGGACTGGCGGGCCGTCGGGAATACCACCCACTCGGCCGGACACTGTGGCAATGCGACGGGGGTCACTTGAGTTCCCGCCGGTGGCGGCACCACGCGCAGCGGTTTGTCGATGACGTCAAGGCGTGCACGCTGCAACAGGTGAGGACTGAAACGGTTGATGACTATGCCGATGACGGTCAAGGTAGCGAGCACTGGGCGCGCGAAGATAGCCGTCAATAACGCCAGCAGGCGCGACTGCCAGCAGATGGAGCCGAAGTGGGCGCTCGCGGGCCGATCCCGCCAATCAGACGAATTCACAGAGCCAACGGTATCAGGTACCGCATGTATTAGATACTATCTGTATGGGGTCCGCTGTAACGCGCGAAGGAGTGAGGACGGTAGCGGTCTGCACGTTCGACAGACCCCTCGCGATCGGACGGGAGGGGCCCAGATCGCCGACTTCACAATGCTAGCCTCGAGGTTTCATGTCGTTGGGGGTTGTGACGGCGTGTAATGCACGGAAGCGCCTGTCCTGCAGGGAATTCTTGGGATTGCTGAAGTCTCAAGATCCTCAAGCAGGAAGGCAACTCCGTAGGTGAAGCGTAACGCAGTTGGTGGGCTGGTCGTCGATGATGTCCGCGAGTCGTTGGTGACGTCATCGGGCGCGGCGATGATGAACGAGACGATCCGGGTTGCGGGCCTGGGGCTTGTCCTATCGAGGGCGCTGGGGCCGTGGCGGCTGGCGCGGGCCCGCCATGATCCGGGCAAGGTGCTGCTTGACGTGGCGATCGCGGTCGCGCTCGGTGGTGACTGTTTGGCCGATGTGGCCGCAGTCCGTGCGCAGCGCGACTTGTTCGGAGTCGTGGCCTCCGACCCGACTGTGTCTCGGTTGTTTGCGGCGTTGGCCGTCGATGACGCCACCACCGATGCTGCGGTCATGGCGCTGCGCTCGGCACACGCTGCAGCCCGTGACCGGGTCTGGTCACGGCGTCGGCCGCTGGCGGGAACACCGGGAACACGAGAGGGTGGGCAGGTCATCGTCGATATCGATGCCACCCTGGTGGCGGCGCATTCGGATAAGGAGGGCGCTGAGGCGACCCACAAGATGTCTTATGGGTTCGCCCCGATGTGCGCTTTTGTCGACCATGGCGAGCACGGCACCGGAGAAACTCTGGCGCTGGACCTACGCCCGGAAAGGCCTCGCCGTTCAATAGTTCTGATCACATCACAGTGCTGGGCGCCGCGCTGGAACAACTGCCCGCCGCCGAGCGGGGCCAGGTGCTGGTGCGCGCCGATGCCGGCGGGGCGTCTAAAGCATTCCTGCATCACCTCACCGACGCCGGATTGCACTATTCCATCGGGTTTCCCGCTCACGGCCCTGTCCAGGCCGCGATCGAGACGATTCCCGAGCAGGCTTGGGTGGCTGCGCTCGACAGTGACGGCGCACCTCGTGAGGGTGCGCAGGTCGCCGAGCTCACCAACTGGATGCCGACCCCGGTCAAACCCACCCGTTCGCCGGCCAAGTACGGCCCCCAGGAATGGCCACGCGGGATGCGAGTCATCGCCCGCCGTGAACGTCCTCACCCCGGTGCCCAGCTACGGCTGACCGACCATAACGGCTGGCGAATCACCTGCTTTGCGACCAACACTCGCGGAACCGGCTGGACGCTGCCGACCCTGGAAGTGCGTCACCGCCAACGCGCCCGCGCCGAAGACCGTATCCGCTGTCTGAAGGACACCGGCCTGCGTAACCTGCCTTTCCACAGCTACCGGGCCAACCGGATCTGGCTCGAAGTCGTCGCCCTGGCTGGCGACCTGATCGCCTGGACTCAAACCCTGGCCTTCGAGCGTCATCAACCCGCCCGCAGCCAAGATCGATCTCGTGACACGGACGGGTGTGATTTGTGATGAGTTTTGGGCGGTGGTCGAGCCGTTGATGCCGTCGCATGACGGTAAGCGAGGCAACAGGTTTCGTGATCACCGGCTGATCCTGGAAGCGATCGCCTGGCATTTTCGCACAGGATGCCCGTGGCGGGACCTGCCCGCCGAATTCGGGCCGTGGCAAACAGTGTGGAAACGCCATCACCGGTGGTCGCTGGACGGCACGTACGACGAGATGTTCGCCCGGGTCGCGGCCTCGTTCGGGTTCGACGCCGACGTGCACGCCGACATCGAAAAGCTGTTATCAGTCGATTCGACCAACGTGCGTGCCCATCAACGGCTCTTCGTAATTCAGAGTGCATTGACAAGTTGGTGGAGTGCTCCGCTGTGTAGTAGTGAGCGCCAACGGTAGTGGGTGAGGTTGCGGAATCCGAGGGCGTTGCGGCGCAATGCTTCCAGGCGGCCGTTGATGGCCTCGGTGGGTCCGTTGGAGACGTGGTGGTCGAAGAAGGCCAGGATGTCGGCGCGGCGGCGCGATAGCGTGCGGCCGAGTTGGGCGATCTCCTCCAATCCGGCGGGTACGCCGCGCCGTATCGACTCGATCAGCCTGGTCATTGCCTTCTTGCCGTGACGTCGGTTCGGGTCGGCGTAGGCGGCGATGATCTTCTGATAGATCAGCCAGGCGACCTTGACGGCGAGATGGTCGTCGCCGTCGAGCACCTCGGTCAGCCGGGTGTATTGGCGTGGGGAGCAGCTGCAGGCGGGTTCGGGCGATGCGCCGGATCCCATAGAGCGGGTCACCGGTGTGTCCGCGCCGACCCAGGGTCTGCTGCTGGATGCGTTGGCGGATCAGGTCGAGCTTGGTCCCGGCCAAAGCCACAACGTGGAAGGGGTCCATCACGGTGACCGCGTCCGGGATGACCTCGGTGGCGGCGGTCTTGTAGCCGGCGAACCCGTCCATCGCAATGACCTCCACGGCCCGGGCAAAGTCGGTGGGTTGGGCGGCCAACCACGTGGCCAGTGCGGTCGCTGAGCGTCCTTCGACCAGGTCGAGCAGGCGTGCCGGGCCGGTCTGGTCGTGGGTAGGCGTGAGGTCGATGATCAGCGTGACGAACCCCTCTGTGCCGCGACGCCGAGGCGCCCAGCGATGCTCATCGACACCGATCACCGTCACCCCGGCCAGCCGATCCGGCCCGGTTGTGGCGATCAGGCCGGCGGTCGCACGCATCGCGATGGAGCTGACAGTATGCCAGGACACCCCGAGTTCGGCGGCGATCGCCGAAATGGTGGTGCGGTCGATCATCAACCGCCGCAATACATACCGGGCACAGCGCCGCGTCGTCGATGAGCGCGGGGCCGCCAACTTGCCCAGATCCTGGTTGAACACTGCCCGCCCACACGCTGGCGTTGTGCAGCGGTAGCGAGGTAGGGCACCCTGCAGCACCAGCGGGTAGCCGGCCACCGGCAGATCCGTCAACGGCCGAGTCACAGTGTCGCGGTAGCGGCCCTCCCGGCCGCAGTCCGGACACCTGGCGTCACAGGCCACCGGCCTGCAGAAGATCGTCGTCGTCTTCTCGTCGACCGCGGCGTCGGTGATCGTCACCCCCAACTCGATGGTGCGCATGATCGTGTCGGCAACAACCGACGGCGGGCAGGCAGTAGCCTCAGGCAAGGGTCACCTCGGTGGTGTTGGTGAAGCGGCGTGTAGGAACCTGAATCGTCACCCACCGAGGCCCCACCTCAGCTCAACGACACGAACCCCCACCGCGGATATCCGCCAACCACTGCTGCACGCTCATTTCCGCAGAGCCCCATCAACACTCGGCGGGCGCCCGTTCGGACACGTTGTGCACAGGGGGCACTGTCGAATTCGAATTACAAGAAATCTGCCGATGAGCCCGACGATCATGCGATCGGGCGTTCCCGCGGCGGGCTGACCACCAAGATCCACGCGCTGACTGATCCTCGCGAAGCTCCCGTGGCGGTCCGGCTCACCGCCGGCCAAGCCGGCGACAACCCGCAATTGATGGCGCTGCTCGATGATTACGCCGCGACATGCAGGGATTCAGACCAGTCCGCTGACGATTTCCGGTTGCTCGCCGACAAGGCGTATTCGCATCCGAGCACCCGTACCCAATTGCGTTCCCGCAGAATCAAGCACACGATTCCCGAACGTCGAGATCAGATCGACCGCCGCAAGGCCAAGGGATCCGCCGGCGGCCGCCCACCGGCGTTCGACGCCGAGATCTACGCGCTGCGCAACACCGTCGAACGTGGCTTCAATCGGCTCAAGCAGTGGCGCGGCATCGCGACCCGCTACGACAAGTACGCCCTAACATACCTCGGCGGTGTACTGCTGGCCTGCGCCGTGATCCATTCGATGGCTTTATCTGCGGTGGAGCTTGCCTGTCTCAAGTAGCAGATCCTCATCTGCGTTGATACACCGGGCGTTCGGTCGTCGCTATCTTGTCAAAGCGACCTCGAAATAATCTCTTTCATTATTTCGTTAGACCCCGCGTAGATTTTCTGTACTCGCTGATCAACCCAGAGACGCGAAATCGGATATTCCGTCATGTATCCGTACCCGCCGTGCAGCTGCAGGCAGTCGTCGAGGACTTTCATCGCCCGTTCCGTCGTCCACCATTTGGCCATCGCGACAGTTTGCACGTCGAGCTGGCCCTGGAGGTGTAGGCAGATGCAGTGGTCGAGGAATACTCGCGCAATCCTTGTTTCAGTGGCCGCTTCGGCCAGGGTGAACTTGGTGTTCTGGAACCCGAAGATCGTTCGTCCGAAGGCCTCTCGTTCGCGCGTGTATTTGACCGTCTGCTGCAAGGCCAATTCCATGGCGGCAACCGCTCCGACCGCAACGATTAGTCGCTCCTGCGGCAGTTGCGTCATCAGCTGGATGAAACCTTGCCCCTCGGTGTCGCCTAGCAGATGCGTCTTGGGGACGCGCACGCCGTCGAAAAACAATTCAGATGTGTCCTGACCGCGCTGACCTATTTTGCTGAGGACTCGTCCTCTCCGGAACCCGGGGCGATCGGCTTCCACGACAATCAGCGAAATACCGTTGGCACCTTGAGTATGGTCGGTCTTGGCCACGACGACAATGAGATCGGCTTGCTGACCATTGGTGATGAACGTCTTCGAGCCGGTGATGACGTACTCGTCCCCATCGAGGACGGCGCGCGTCTTCACGCTTTGAAGATCAGATCCGGTTCCGGCCTCCGTCATCGCAATGGCACCGATCAATTCGCCCGACGCCATCTTGGGCAGCCACTGCCTTTTCAGGTCTTCCCGGGCGTAGTGCAGGATGTAGTGTGCGACGATGCCGCTGTGCAGGCCGGCGCCCCACGAACTGTCCCCGATTCGAGCTTGCTCTTCGAGCAGAACTGCCTCGTGTGCGAATGTCCCGCCGCCGCCGCCGTATTCGACCGGCATCGACATGCACAGCAGGCCCAGCTCGCCTGCTCGTTCCCACACCGCCCGGTCGACATGGTGTTGCTCGGCGAAGCGCTCTGAGTGGGGTGCAATCTCAGTGGCAACGAACTTTGCGGCGAGATCACGAAGCGCTTCCAATTCCGGGTTGAGCCAGGGTGAGGCGGCTGTCATAGGGAGGCGTCCTTTCGGTTAGCTGCCGTGAGATATCCCGCATTAGTGCTTTGCACAAGCATAATCTTTCAAACTGTTAATTGGTGAACGAGTCTGATATGGGCGGAGGTTCGTAGATGAGTTCGCTGTAGTTGTCGCGCAGCGCGTCGATGATTTCCGTGAGGGGAAGGTCGTCGAAAACGCCACGGTCATGGAGGTATTCCATGTGTTGGGAGCCGTCGCCTGTGTGAGCGTGCAACATGGCGTCTCGCTGACCGTCGAATTCGATAGGAGGGACCCCGAAGCGCGCGCATAACTCGCGGTTGAACGCCGGCGTGGCCTTGACCCACCGGCCATTCAGCAGCATTTGACTGTAGCCGTGGTAGACGAAAACGTCCGAGCCACCCATCCGTTCACGGAGACTCGGGGTCTGCAGATGGTTGCGGACGTCGGCGAAACCCAACCGCGCCGGAATCCCCGCGGCGCGACACGCAGCCGTCAAGAGCACCGCCTTGGGGACACAGTAGGCGCGCTCGGCGACGGCGACCGCGCTGGCTCGGTACTGGCACGGGTCGTCGGAGACGGAATACGGGTCGTACCAGATCGAATCACGGACAGCGGTGAAGATGCGGCACGCCTTATCGACGGAATCAATGGCGTTACGCGTCGCCGATTCGGTGAACTGCTGCACGGCATCGTGTTTCCAGTCGAGGAATTCGGTGGGTGCAAGGAACCGCGCGAACTCTAACTTCATCGGTGGTGGAGCCTGATCGGTAACCCGTCGACCGGGATCGGCAGCGATGTGTTGTCCCAACGGATGCGGTAATCGGTGTCGAGGCCGAAGGTGAACGTGCGCAGCATCTGGTGCAGGATCGCTTTCACCTCGAGGGTGCCGAAATGCATACCGATGCATTTGTGCGCGCCACCCCCGAACGGCAGCCACGCGAAGCGATGGGCTTGGTCTTCGCGGCGTGGGACGTCGAAACGTAAGGGGTCGAAGCGATCCGGGTTATGCCAGACTTCGCGGACGAAATGGTTGACGGCGGGAGTGATCGCCACAAGCGTGTCGGAGGGGATGTAGTGGCCGTCTATTGCGGTGTCTTCCACTGTTTTGCGCATCACTAGCGGAACCGGCGCCACGAGTCTCATGGATTCCTTGATCACCAGATCGAGGGACCTGAGCCCTTCCAAATCATCGATCTCCGGTGACCGGTCGCCGAGAACATCGCTTTCGGCGCGAACCCGATCCTGCCATTCTGGATGCTTTGCCAGGTAATAAGTTACCGCGGTGGTGGTGATCGTCGATGTGTCGTGAGCGGCCATCATCAGAAAAATCATGTGGTTGATGACATCGGAGTCACTGAAACGTTGCCCGTCTTCGGTGCTGGCATGGCACAGCGCCGAGAACAGGTCATTGCTGTCGCCGGCCCGGGCGGCCGGCAAGTGCCGGGCGAAGTACTCCTCAAGCACCCGTCGGCCGCGGACCCCGGCGCGATAGCGGGTACCGGGAAGCGGCGCGCGGACGAGCGAACTGGCCGCGCGTACCGTAGCGACGAACGCCTGGTTAATGGCGTCGCTGCTGTCTTTGCCTCGGCCACCCATGAACACATCGGTGGCGATGTCGAGGGTCAGGTTTTTCAACAGCGGGTACATGCGGACGGACGGGCCGGTCGGCCACGTGGGCAGGGTTGCGCGGACGCAAGGGGTCACTTGGGTGACGTAGCCGGCCAGTCGCGGCCGCGTGAAGGCCTCCTGCATGATGCGCCGGTGCATGAGGTGTTCGTCAAAGCTCATCAGCATCAATCCGCGGTGGAAGAACGCGTCGATGAGAAAGGCCCAGCCGTCTTGCGAGAACGCCTTTGCGTTGGTGGTGAGCGCCTCTTGGGTAGCTTGGGGGCCCGCGATGACCGCCATTTTGGTACCGAACGCTCCCATCCACGAGACAGAACCGAACCGCTCGTAGCGCTCTCTGCCCAGGTCGGACCCAAACCGGATGTAGTCGAGGGTGTGCCCGACCAAGGGGAGCCCGGCATCACCGAGAACCGGTCGCAATCCGCTTCCAGCCGGGGGGCTGCCAGTTCACGCACTGGCCACCGCCGACTCCACCGGCGAAGTCCGTCGTCCACCCGTTGCGGCGCGGGAATCAAGATGACCGAAGATAACCGTTCCCGGGCTTTATGGCTTTATCGACGGGCGCGTGTAGCGGGTTAACCATTGTCGCTCCCCGGCCTGTGGTCGTCGTTGGCGGCCTGCTCGCGATGAGGAACCGACCAGCTGTTTACATTACGCCCAATAATGTCAAAATTAATACATGCATATCTGACTTGTCAACGGGCTCCCAGTGGCGCGCAAAGGCGGTCGCCGCGCAGCTAGCCGCTGCGCCCGCGTTCAGCTCCGGCGTCAAGGAAACTTGCGTTCAGCGCTGTCGGCGAGAAACGCCCCGCTGAGGCGCAAAGCGTGACGCGCCTCGGGCAAGAGTCGAAACAGGGCTTGAAACACGTGAATTTGACCGCGAAACACCTGAAGTTGCACGGACGACCCCGCGGCGAGCATGCGCTCGGCGAGTCGTCGGGAATCGTCGAGCAGCATTTCTCTCCCGCCCACCTGGATCAATGTCGGCGGCATGCCGGTGAGGTCGGTGGCGAGCACGTTGACGCGGGGGTCGTGCGGATCGGCGTCGCCCACGTAGAGACTCAGCGCCCGCGACGCGGATCGGGCGGATGCGAAAGGATCGCGGCGCCAGATTTCGCGAGCCGTCGCCAGCTGACACGTCAGATCGATGACGGGGGACATCAGTAGCATGCGGTCAGGCAACGGCAGGCGATGTGCGAGTGCACCCAACGAGGTCGCGACCGCCAGTTGGCCGCCCGCCGAATCGCCTGTGTCGGCGGCAAGTGAATACTGACCAGTGCGCGGCCGACTCCTGATCAGTTTTCGATTGCCGTTGACAGCCTGCGATCGCTACCGTGCGGGCTGATGTCGATTCTTCAGAGCCCGCCAACCACCGGTAGGCCCTCAGTGCGTCGTCAGCAGCCGCCGGATACGGGTAACGCGGAGCCAATCGATAGCGGACCGCGAAGACCGGGCGCAGCGACGCGGCAGACAGTTCGCCCAGCAGACCGCGATGGGTTTTGGGAGAGCACATCGAAAATGCGCCGCCGTGAATGTAAAGGATCGGTGGCCCGTCCGGGTTGACGTTCGGTGCGACGACCCAATCTCCCCTCACTCGATCGCCGGCGAAGACGGTGTCGACCAGCCTTACGCGCAGTCCTGGGCGTGGGCGGGACGCGATGAGCGCCGCCCGAAGCACCCGATCCATCACAGCAAGCCCGTACTGGTTGGACGGTAGTGCTTGCGTCAATGGGCGAAGGACCCCGCGTGCGGATGTTGCGATGAGGTAGCTTGTCAGGCTCGGATCCCAATCCGAGGAAACGGATATCACGATAAGCCAGCCAGCTTTTCGTTGGTGCGGCCCCCTGTAGCATCCCAAAGCCCGCGTATAGCGGATCGAGGTCGCTGGCGCGGGGCCACGTCGTCTTTGAAGTGGTGGGTATAAGAAGGAAGCAGGCCTTGTAGGAACCACTGTTACTGATCTACCGGCAGCCTTCAAAGCGACGCGCGCCGTCGTCGCCAGAGCCGCAGAGCTACGCGATCCAGAGCGGGTCGTCCCCCGGTCGAGCTGGCGCAGGAACGTAGGCAACGATGATGCAGCGACGGCTGTCGAAGTTCTCGATTACCGCCGACCGGCCGGCAGTTGCAAGGTCGCCTCACTGGGCACGCATATGCCCTCCTCGCTGGACACTGCCAGTTCCAGGTCGACCAGGCGCATTCCGCGGTCTTGGCGCTTGGCCACCACCCGCCCGGTAAGGGTCGCGGTCTGTCCCGGGTAGATCGACTTGATCATCGATATCTTGCGCCGGCGCAGGAGCGCGTCGGGGCCCGCCCAGTCGGTGAGGCCCCGGTCGATGAAGCCGTGAAAGAACAGCGTCGACAGGTAGATCGTTCGCTGGCCCTGGCTGCGTGCGTACTCCGGATCGTGATGGCCCGGGAACCAGTCCCACGTCGCCGCGGCGTTCATGCAGACCCGCTTGTAGGTGATAGGAATCGACACCGGCGTGATCTCGTCGCCGACAATGACGTCATCGAAGGTAAGGCCTTTGATGTCTGCAGTGCTGATCTTGGTCATGAGCGCCCCCGGGTTTACTGGGCTGTGTCGTAGCGGAACAGGACGTTGGTGTTGCGGGCGATGTTCTCGCCGTGCTGGTCGGTGTAGGTGGTAAGCGATGTGATGAAGACGCCGGTTCCCAGCCGAGTCGTCTTCTCGTCGGATAGCGAGACGATCTCCTCGACTATCCAAACGTGGTCACCGACTCGGGGTCGGCGCTCCAGCTCGGTGGTGGTGGAGGCGTTGATGATGTGGTGGCCGGGCAGGGGAACGTTGAGCGCGAAAAGCCCGTCCTCGCGGTGCAGGTGCGCGGGCGCCCATTGCGGGTTCATGCCCAGGGTCATCAGCAGGCCCGGTGGGCACTCGTCGCCCTCCCAGTACCGTGGGTTGGCGTCCTCAACCAGAGAGCAGTAGTAGAGGATCATCGATCGGTCGATCGGAAACCACGCCTGCTTTGGCTCGGAGCGACGACCGACCCAGGACCGGCCCTCCTCTAGAGTGCCGAACGCCATCCCGAGCCCGGTGACATCGTTGGTGTGGGAGCTCACGGTGTTGCCTTCCCTTCGATGGCGGGTTCGGGCAGGGGCATGCGGGACAGGATCGAACACATCGACTTGCCGGTCTCGTCGAAGCGCAGTGTTGCGGTTGCGCCGCCGCCGAGGGCTCCCCGCATGACGATGTTGAACGCATGCAGGCGAGGCAGCGTGTAGATCGTCACGGTTCCGGTGACCAGACCCTTCATGAAGGAGGTGATGGCCTCCGGCCGCAGTCCGCGTTGCAGCGCGGCAAAAGCCTCGGCGTCGCGGGCGAGCACCACGACGTTGGAGATGTCACCCTTGTCGCCTGAACGCACGAACGCCAACTCGTCAATGGTGGGCATCGAGCATCTCCTTGGCGGCCTGGACACGGACGTGCTGTGGGACGAACTCACGCGGTACCAGGGTCGGCCACAGCGCTATCACCTTGCGCACCGCCAGCGGCGCGCCGAAGGCGGTACCCACCGGACCGGCCGTCGCTGGCAGCAGCATCGCGCGGCGGGCGACCTCGGCCTCGCTGCGGGTGCGGCACTTGGCCACCATCCGGAGCTCGACCTCGTTGGGCTGGGCGTCGGGTGCCGGTCGTGGGGCCACCGGGCCGGCCAGCGCGTCCCAACCGACACGGTCGAAACGCATCTCCTGCGGAATGACACCCAGGTACTTGATGCGGCCGCGCACTAGCCTCTCGCAGAAGTCGGCCTTCTCCAGAGCATCGGGCCAGGGGATCATCGTGCGCCCCTCGGCGAGGTAGCCGTCCTCGTAGCCGATCTGCACCTTGAGCGTGTCCGGCCGTCGGCGGCCGGTCATGCCCGTGAGCTGCACGCGGTCGGGGCCGAGTTCTTTGACCTCGACACCGCCCATGTCGACGACACCGTCGGGCAGCAAATAGCAGAACGGGTCGTGCACTTCGTAAAGCAAATGCTCTTTGATGGTCCACTCGTTGAGCACCCCACCCGAGCCCGGCACCTTACTGATCACAGCGGTGCCGTCAGCCGACATCTCGGCCATCGGGAACCCGAGCCGCCACGGATCACGCGACAGCCGCCACTGCGAGGACATGCCGCCGGTCGCGATGCCCGCACACTCCAGTACATGACCGACGGTAAGCGCGGCGCCGATCAGGTCGGGATTACGCTCAAATATCCACCCGAAGTGGCGCATGAGCGGCCCGCAATAAAGCGCAGAGTCGGCAAGCCTGCCGCCGATCACGACATCGGCGTCGCCGTCAAGTGCGTCAATGATCCCGTCGGAGCCGGTGTACGCCGAGACAGCGACGATCCGGTCGGCGATGCGGTCGATGTCTTCTTCGCCGGACTCAAGGTGCGCGAATTGCCAACCCGAATCCCTGATTTCGGCGATTCTCCCCGTCAAGTCGTCGCCCTCAATGGTTCCGATGCGGGTGTCGGGATATCCGGCGTCACAGGCCACTCGCGCAGCGGCCAGTGCGGCGGCACCCGGGTTCGCTCCGCCCCCATTGGTCACGATGCCGACGTCGTTACGGCGGGCAGCGGGCAGCGCCTGACGCAGAATGGGTTCGACATCGGGCACGTACCCTTTACCCGGGTCACGCATCTTGGCACGGGTAAGGAGCGCAACGGTCAACTCGGCCAGCAGGTCGAAGCAGGCAAACTCGACACCGCCCTGCTCAATGAGTTCCACCGCGGGATCCACCATGTCACCCCAATAGCCGGCACCAGCACCGATCCGCACGCTGGCACTCATGCGCACTCCTGCGCCGCCTCGGCGCTTGCCGCCGCGATGTCGGCACTAGGCGGCGGCGCGCTTGGCGGTATCCCGCCGACTGCCGGATCGACAAAGGGCACGAATGCGGCGCGCCCGGCCAGCCGTCCTTTGCCGGTGACCCCCGCAGCAATCAGCATCGTTCCGGGCATCGTGTTTTCCTCCTCTCTGTCCCCGGCCGTCGACCGCAAAGCTCTTGGCCGCGGGCCTGTTAATTGGCGTTAGCGTACGCTGTCTTGACACCGCTCGGCAGTGACCCGAGGCCCGGCGTCCGGGTCAAGCGAATCGAGCTTCCCGAAGTTGTCGACGTTGCGCCACGCCAGAGGGGCGAGATTGCCTTTCTGCTCATGGGCTGGGGATTAGAACGACTCCGGCTGCTGCCGAGAAATCACGTATCCGGCGTGGCGTAAAGCCGGTCACTGGAAGTCGACGCACTACCGACACGCGGACTTGCGCGTCAATGTTAACGGCCGATAACGTATCACCGGGCGATTACGCTGCTGTCGAGCGGTGACGGAAGCTTCCCTCGAATTCCTCGGTGTGTCGCCTGAAGTTTGTCGTGGCCGGTGCAAACCCGGACCTGCGGGTGATTCAAGGGGTTGAGCGGTATGGAGATATCAGAGAGCCAGGAACGGCGGGATCTGCGGGCGGCGGTTGCGGCCATCGGGAAGTCGTACGGCCACGATTACTACCTGACCAAATCCCTGGGGGGCGAGAAGTCTACGGAACTGTGGCAGGAGGTAGGTAAGCAAGGTTTTCTCGGGGTGAATATTGCCGAGGAGTACGGCGGTGGCGGTGGGGGTATCTACGAACTGCATGCCGTGGGAGAGGAGTTGGCGGCGGCGGGGTGCCCGTTGTTGATGACGGTGGTGTCGCCGGCCATTTGTGGCACCATCATCCAAGCGTTCGGAACCGACGAGCAGAAACGGCGTTGGCTTCCGGGCATTGCGAGCGGCGAGATCATAATGTCGTTTGCGATCACCGAGCCCGACGCGGGCTCAAACTCGCACAACATAGCGACGACCGCCAAGCGGGACGGCGCCGACTGGGTTCTGCGTGGCACCAAGTACTACATCTCGGGAGTGGACGAGGCGCAAGCCATCTTGGTGGTCACCCGAACGGGTACTGACGAGCGTGGGCGCGGCCGGCTGTCGCTGATGGTGGTTCCCACGGACGCTGCCGGCCTGCAGAAGACTCTGATTCCCGTGCAAGCCGTGACACCGGAGAAACAGTTCACCCTGTTCTTCGACGATGTACGTGTTCCCGGTGACAACTTGATCGGCGCTCGGGACGAGGGACTGCGGCAGGTATTCGTTGGTCTGAATCCGGAACGGATAATGGGGGCGGCGCTGGGCAATGGGATCGGCCGGTACGCGTTAAACAAGGCATGTACCTACGCCCGGGAGCGCAGGGTGTGGGACACCCCTATAGGGGCACATCAGGGAGTCGCTCATCCGCTGGCGCACGCCAAAATTCAGGTTGAACTCGCACGCTTGATGACCCAACGGGCGGCCGCCTTACACGATGCCGGCGAGGCAGGGGCCGGCGAGGCGGCGAATATGGCCAAGTACGCGGCAGCTGAAGCCGGAATCCTTGCGCTGGACCAAGCGATTCAGACGCATGGCGGCAACGGTCTGGCTACGGAGTACGGGTTGGCGACGTTGTGGGGACCGGCGCGGTTGATGCGGACGGCACCGATCAGCCGGGAGATGATCCTCAATTATGTTGCGCAGCATAGTCTCGCGCTTCCACGGTCATACTGAACGTCGACTAGGTTTGGGTGGCTGCTTCCATGAGGTCAACGTGAGAACTTGGGCACTTGCCAGCGAGCCGGCTATCGCCGCAGTAGAAGAACTACCGCCAGGAAAGTACGAAGGCCACGACGGCGCGGGCATGCAGGAGTTGGTGCTTCGTCGGTTTCTGCAGAGCCATTCACTTGGTCCCCGCGATGTGGACGGCCTGCTGGTTTGCCCGTCCGGCATGGCCAGCGGTGCGGGTGCCGACATCTTCGTCCACGAGCGCCTCAATGACGTGTTGGGCATCCGGCCGCGCTTTTGTGAGACTGTCAACGTCGGTGGGGCGACCTACACGATCATGCTGTCGCGGGCTGCACTTGCAATCAGCGCCGGCCTTGCAAACGCGGTGCTCTGTATCGGTGCGGGGAAATTCCCCAAGGTGGGGCGGGGAGGCGGCGCCAACGCAATGGCGCGCATGATCAGCCACCCGGACTTTGAGTACCCATACGGCAGCTTCATCCCAGCCCTTTACGCCTTAGCCGCCACGCGGCATATGGCCGAACGCGGAACGAGCCGCGATGCTCTTGCCGCCGTGGCGGTCTCGAGCCGCGAGTGGGCGTTACGGCATCCAGATGCTTTGATGCGCAACGCGGGTCCGCTCACCGTCGAGATGGTTCTGGCTTCACGACCTATCGCGTGGCCGTTCAATTTGCTGGACTGCTCAGTACCGTGTGAAGGTGGCGCCGTGTTCCTAGTGGCCCATGGTGACCGCGCGCGGGAAATCACCGACCAACCGGCCTATGTATTGGGCTTCGGTGAACACCACGATCACGGCAACATCACCCACACCAGCGACTTCGCAACAATGGGTGCCAGCGTGTCAGCGCGTGCCGCGTTCGAAATGGCCGATCTTTCGCCTTCGGACGTGCAGGTGGCCGAACTGTACGATGCCTTCACGATCAACCCGATACTGCTGTTGGAGGAAACGGGGCTGGTGGCGGCAGCTAAAGGTGGCCACTTCTTCCTGGATGGGCGGGGGGCGCCCGGCGGTGACCTTCCGGTGAACACCTACGGGGGTCTGCTGTCATTCGGACACACCGGCGACGCGTCGGGAATGTCGATGCTGATCGAAGCTGCGCGCCAAGTGATGGGGAAGGCTGCGGATCGTCAAGTGTCTGCAGAAATAGCATTGGTACACACTTACGGCGGCATGATGGCAGACCATTCGACCGTACTCTTGGGGAGGACGCCGTGACAACTGCTCCCATGCCCACCGTGACTGACAGCACGGCCGTGTACTGGCAGCAGGCAGCTGTCGGGCGGTTTGTGCTCCCGAAATGTCGGGAGTGCAAGCGATTCCATCATCATCCCCGCCCTTGGTGCCCATACTGCTGGGCTGCGGATCTGGATTGGCAAGAACCTTCGGGAAAAGCGACGATCGTCACCTACACCGTCGTCCGTCAGGCCCCGTCGCCAGCTTTCACCGCTCCTTACGTCTTGGCGATAGTGGAGCTGGAAGAAGGACCTCGAATGATGACCAACGTGATCGAATGCAACGTCGATGAAGTGCGGGTCGGTATGGCTGTCGAGGTGGTCTTCGAATCACGAGGCAACCTGGCACTTCCGCAGTTCCGACGGGTCACGTCAACTGCGTGACGAGCCGACGCGAAAACTCACTTATCCAGCACCGATTACCTGTATTTGTGGGTGGATGGCATCCACCTCAAGGTGCGCCTTGAGGTGGAGAAACTCTGTTTGCTGGTAATGATCGGGGTCCGTGCTGATGGCCGCATGGAGCTCGTCGGGCTGGCTGACGGCTTCCGGGGATCGACTGAGTTCTGGGCTGATTTGCTGCGCGATTGCCGCCGCCGCGCCATGACCGCAGCGGTGCTCGCGGTCGGCGACGGCGCCCTGGGCTTCTGCAAGGCGTGCGGGAGGTGTTCCCGGATATTCGAGAGTAGCGCTGCTGGTGGCATAAGCAGGCCAATATTCTTGCCGCACTGCCGAAATCGGTGCACCCAGGGTGCAGTCGCGGCGATGAAGGAGATCTACAACGCCGAGGATATCGACAAAGCCCAGCTCGCGATCAAAGCGTTCGAGATCGACTACGGCGCCAAATACCCCAAAGCGGTCGCCCAAGATCGTCGACGACGCCGAGGTGTTTTTGGAGTTCTACCGGTATCCCGCCGAGCATTGGATCCACCAATCGCACCACAAATCCGATCGAAAGTACCTTTGCGACAGTACGTTTGA

Protein sequences of DBSCAN-SWA_1

>NZ_AP022614|5058706:5110212|5099879_5100536_-|WP_007172209.1|DBSCAN-SWA
MKLEFARFLAPTEFLDWKHDAVQQFTESATRNAIDSVDKACRIFTAVRDSIWYDPYSVSDDPCQYRASAVAVAERAYCVPKAVLLTAACRAAGIPARLGFADVRNHLQTPSLRERMGGSDVFVYHGYSQMLLNGRWVKATPAFNRELCARFGVPPIEFDGQRDAMLHAHTGDGSQHMEYLHDRGVFDDLPLTEIIDALRDNYSELIYEPPPISDSFTN
>NZ_AP022614|5058706:5110212|5079243_5080278_-|WP_040624304.1|transposase|DBSCAN-SWA
MRQISDRYLSEEERIGIADLRRTGMGVRQIATTLGRAPSTVSRELRRNSRRDGQYRPFEAHRWAVQRRARRHQRRVDKNPALCDLIAELLAQRWSPQQIARHLRREYPEDRLMWLCHESIYRAVYQPHSRLIRPPQVRSSHRGPLRTGRTHRRAHQRPGRRRPRFAQPMLSIHQRPFAPADRSQPGHWEGDLIVGKNQRSAIGTLVERQTRLIRLMHLPTRDADSLRIAIATTMGGLPSNLIRSITWDQGIEMARHTDITADLGVPVYFCDSRSPWQRGSNENANGLLRQYFPKGTSLSTYTPDHLRAVEYEINNRPRHTLEDRSPAELFTALLTSPDHQLLRR
>NZ_AP022614|5058706:5110212|5063904_5065374_-|WP_162839945.1|integrase|DBSCAN-SWA
MILSFFSSQGWQSWGVEHRPVIPEGMPVLIDDDLLFEDGPAVPRPTTVINRWLRLLPASGAPAPSSWENYARAVKEWTEFLAEHGVGLFDSRDRLKAGLSRYAEHRAAGAIRARFAATTWAQHMSILSLFYRWAMDEGYAEAEPFTYRSARAVFAGTGRDVRVNLAVRRTPKPHVTIKYLEPDFTDLFRKGLRGLAPDGTRDTGFAGREMTRNAAIGDLALATGLRLGEFTHLLPWEIPALPPAPTVIPIPFPVPAGITKGRKFRTTWISYDALAGLHDYLQLDRAAVTDGSAWRPPRRRGEPLQVTEPDARGGRINGVRRSWESLTPAERRRLVAPEGGSCLLAVKGDGGPFTAWATVFERTSDRIRARFEPRFPHVHPHRLRHSFSMQTLEYLVTGYYRQAAKLVCDTDADAALVFYLTKADPLLVLRDLLGHSTVLTTEKYLKRLDTTRIYRQAYETAGAAAGLTEDTAAQREADAEFDDDTEEEL
>NZ_AP022614|5058706:5110212|5076781_5077222_+|WP_007172194.1|DBSCAN-SWA
MRADNTRHLIVAARQRHELTRAKAIQALRTLDAEGRPVTFEAVAQAAAVSRSWLYAQSDVRAEIERLRAAHRRAPATPVPARQRTSDASLLRRLEAANQRNRKLAEENRTLRDQLARALGQQRTASETTSTRTPRKRLSSITIGPC
>NZ_AP022614|5058706:5110212|5103515_5103968_-|WP_007172211.1|DBSCAN-SWA
MTKISTADIKGLTFDDVIVGDEITPVSIPITYKRVCMNAAATWDWFPGHHDPEYARSQGQRTIYLSTLFFHGFIDRGLTDWAGPDALLRRRKISMIKSIYPGQTATLTGRVVAKRQDRGMRLVDLELAVSSEEGICVPSEATLQLPAGRR
>NZ_AP022614|5058706:5110212|5078622_5079243_+|WP_007172196.1|DBSCAN-SWA
MRKAKMYPSPCAACGQQAVLIGFDPDERQICGPCSGSTLDYRCANCGQPGIRAHNRCSRCHTAELLHNALAGPDGQIPAQLKPLADALANANDPRSVAVWLGKSAAAELLMNLARTGQTITHHALDQLPPGGHVNYVREILVRTAVLTPRNEYLERIEPWVDRHLANYPAEHARLVRSYTIWYLLHRARRAKQPLSNPGCQRRGGF
>NZ_AP022614|5058706:5110212|5082534_5083146_+|WP_007172200.1|DBSCAN-SWA
MSVDVPFRAAPDSETGTGGSTAILDAARAVATAGGFKAVRLKTVAKQAGITVGSLYDHFASKTDLLVTLLAREFERVNQERDWSTCAASPSDRLGSLTARLHDEWQQNLQLTEAVVRAFVMAGTDEALTVQHAADVVESMLARTVGGPTQGACERQIAGVIADIWLANLMAFVVGRATAAEARERIDRGLQRILAAWNASKSA
>NZ_AP022614|5058706:5110212|5075671_5076166_+|WP_085271075.1|DBSCAN-SWA
MQTLETTGAPITFTAVAKAAGVSTWLVYADGIREHIDAARHRQSNHHRRTDTPAASSTHPATPDSLRADLAIAREQIKTLRTERDKLQQRLRLQLGAELEAPDRAHLTARVVDLETINRQLVAERDARAIEAQTAKGRVTELEDELSAARESLRRVIKAQNRAP
>NZ_AP022614|5058706:5110212|5089660_5092594_-|WP_007172562.1|DBSCAN-SWA
MTDDRAAGLPHMPVFARTVHKLAVPVVFAWVGLVVVLSVLVPSLDAVAEEHTVSMSPKDAPSMQAMKHIGKVFNEFNSDSAVMIVLEGDKPLGDEAHHFYDQIVRKLEADTKHVQHVQDFWGDPLTAAGSQSSDGKAAYVQAYLAGNQGESLASESVAAVRKIVDSVPAPSGVKAYVTGAGALIADQHSAGQKSLQKVTIITFVVIIVMLLWVYRSIITVFSTLFMVVIEVMAARGVVAFLAYNNIMGLSTFAVNILVLLAIAAGTDYAIFILGRYQEARGLGEDREKAFYTMFHGTAHVVLGSGLTIAGAMYCLSFTRLPYFQTMGIPCAVGMLVAVAAALTLGPAVLTVGSFFKLFDPKRKMRTRGWRRVGTAIVRWPGPILAVSVAIALIGLLALPGYQTNYDNRLYLPPSVPANIGYAAAERHFPASRMNPELLMIETDHDMRNPAGMLVLDRIARGVFHIPGVARVQAITRPLGTPIEHTSIPFQISMQNTTQVENQQYMHQRMDDMLKQADAMQQSIDTMQRMYNITSQMAAVTHHMDGLTHEMLDVTNTLRDNIANFDDFFRPIRSYFYWEKHCFDIPGCWSLRSLFDALDGLDQITEKFTYLAGDISQLDALMPQMLAQMPPMIATMTTMKQMMLTMHSSMSSLYDQMDVMSQNSTAMGQAFDAAKNDDSFYIPPEVFDNPDFKRGLKMFLSPDGHAARFIISHEGDPATPEGISHVEPIKNAAKEAIKGTPLEGAKIYLAGTAAVYKDMRDGSKYDLMIAAIAAASLILIIMLIITRSLVAAVTIVGTVLISLGASFGLSVLVWQDIIGFKLHWMVLAMSIILMLAVGSDYNLLLVSRFKEEIGAGLKTGIIRSMAGTGAVVTSAGLVFAATMASFIFSDLKVVGQVGTTIGLGLLFDTLIVRSFMMPSVAALLGRWFWWPQQVRTRPASQLLRPYGPRSAVRAYLLPRQDDPQSATTDRFPAASPHY
>NZ_AP022614|5058706:5110212|5093617_5094628_-|WP_033721600.1|DBSCAN-SWA
MNSSDWRDRPASAHFGSICWQSRLLALLTAIFARPVLATLTVIGIVINRFSPHLLQRARLDVIDKPLRVVPPPAGTQVTPVALPQCPAEWVVFPTARQSDRVIVYFHGSALVTLGLNSHRRFVGKLSQETGARVFNVGYRLAPQARLEDAVSDGLDAYRYVMSLGFSADRIVLAGDSAGGMVAAGTALAARDSGLPVPAGQALMSPLTSSDMGLKYRALKDHRDVMFPFMTVKFLYDVFGTVNGTRAAPVMPSEADLHGLGPFLLQVGTHEMLLNDTLTLADRLRAHGVPVWVQQWHKAMHMFQLGFDVNPDALRAVEEVAMFIRHLTTAPEKNSA
>NZ_AP022614|5058706:5110212|5106831_5107986_+|WP_007172216.1|DBSCAN-SWA
MEISESQERRDLRAAVAAIGKSYGHDYYLTKSLGGEKSTELWQEVGKQGFLGVNIAEEYGGGGGGIYELHAVGEELAAAGCPLLMTVVSPAICGTIIQAFGTDEQKRRWLPGIASGEIIMSFAITEPDAGSNSHNIATTAKRDGADWVLRGTKYYISGVDEAQAILVVTRTGTDERGRGRLSLMVVPTDAAGLQKTLIPVQAVTPEKQFTLFFDDVRVPGDNLIGARDEGLRQVFVGLNPERIMGAALGNGIGRYALNKACTYARERRVWDTPIGAHQGVAHPLAHAKIQVELARLMTQRAAALHDAGEAGAGEAANMAKYAAAEAGILALDQAIQTHGGNGLATEYGLATLWGPARLMRTAPISREMILNYVAQHSLALPRSY
>NZ_AP022614|5058706:5110212|5109225_5109615_+|WP_033721568.1|DBSCAN-SWA
MPTVTDSTAVYWQQAAVGRFVLPKCRECKRFHHHPRPWCPYCWAADLDWQEPSGKATIVTYTVVRQAPSPAFTAPYVLAIVELEEGPRMMTNVIECNVDEVRVGMAVEVVFESRGNLALPQFRRVTSTA
>NZ_AP022614|5058706:5110212|5098660_5099803_-|WP_047324229.1|DBSCAN-SWA
MTAASPWLNPELEALRDLAAKFVATEIAPHSERFAEQHHVDRAVWERAGELGLLCMSMPVEYGGGGGTFAHEAVLLEEQARIGDSSWGAGLHSGIVAHYILHYAREDLKRQWLPKMASGELIGAIAMTEAGTGSDLQSVKTRAVLDGDEYVITGSKTFITNGQQADLIVVVAKTDHTQGANGISLIVVEADRPGFRRGRVLSKIGQRGQDTSELFFDGVRVPKTHLLGDTEGQGFIQLMTQLPQERLIVAVGAVAAMELALQQTVKYTREREAFGRTIFGFQNTKFTLAEAATETRIARVFLDHCICLHLQGQLDVQTVAMAKWWTTERAMKVLDDCLQLHGGYGYMTEYPISRLWVDQRVQKIYAGSNEIMKEIISRSL
>NZ_AP022614|5058706:5110212|5104491_5104827_-|WP_007172213.1|DBSCAN-SWA
MPTIDELAFVRSGDKGDISNVVVLARDAEAFAALQRGLRPEAITSFMKGLVTGTVTIYTLPRLHAFNIVMRGALGGGATATLRFDETGKSMCSILSRMPLPEPAIEGKATP
>NZ_AP022614|5058706:5110212|5077447_5077774_+|WP_007172195.1|DBSCAN-SWA
MIKKMGYQWRLRALMAQRELYQTTDLVPLLAERGVVLSREQVFRLVTAPPQRLSMDVLAALCDILECSPNDLIEIEAVNQSVKKAAGDSPREVPKVRRTTVRRPDRSS
>NZ_AP022614|5058706:5110212|5103982_5104495_-|WP_007172212.1|DBSCAN-SWA
MSSHTNDVTGLGMAFGTLEEGRSWVGRRSEPKQAWFPIDRSMILYYCSLVEDANPRYWEGDECPPGLLMTLGMNPQWAPAHLHREDGLFALNVPLPGHHIINASTTTELERRPRVGDHVWIVEEIVSLSDEKTTRLGTGVFITSLTTYTDQHGENIARNTNVLFRYDTAQ
>NZ_AP022614|5058706:5110212|5081506_5082106_-|WP_033717415.1|DBSCAN-SWA
MPSANIRSLRDRRRAELISEIQNTAHQLFAERGFAAVTTEDIAAAAGISISTYFRYAPTKEDLLVAPVRQTVAEIVASYRAQPSDASATETLMRLLIETAWDKANQNLQYWREAIRTAPHLLGESALISENDNHRLIELVATHMDVDAVTDIRPSLLVHTGLATAQFILRRWLSTDTKTSPPLHIQLEQALRITLAGFD
>NZ_AP022614|5058706:5110212|5083782_5084679_-|WP_033717417.1|DBSCAN-SWA
MTISQERIRTSDGITLVADCYRHAATRPVVLLLHGGGQNRHAWATTARRLHSHGYTVVAYDTRGHGDSDWDPIGQYDVERFVSDLISVRGHVSADSPPAVVGASLGGLIILATHLLAPPDLWAAVVLVDITPRIEFHGARRVVSFMAAHPDGFGSLNDAADIIAEYNPRRARPENLDGLHKVLRQRSDGRWIWRWDPAFISSNFDVLQGNLMTGSEEFDAISGFLAEGARRITAPTLLVRGALSDVVSQETVNEFLQLVPHAETTDVTGTGHMVAGDNNDAFTAAVTDFLDRTTRTPT
>NZ_AP022614|5058706:5110212|5109666_5110212_+|WP_157679851.1|transposase|DBSCAN-SWA
MDGIHLKVRLEVEKLCLLVMIGVRADGRMELVGLADGFRGSTEFWADLLRDCRRRAMTAAVLAVGDGALGFCKACGRCSRIFESSAAGGISRPIFLPHCRNRCTQGAVAAMKEIYNAEDIDKAQLAIKAFEIDYGAKYPKAVAQDRRRRRGVFGVLPVSRRALDPPIAPQIRSKVPLRQYV
>NZ_AP022614|5058706:5110212|5069151_5070261_+|WP_085270300.1|integrase|DBSCAN-SWA
MLVQRVLMPTSSLESWTVLGDGGGSVEPIERYLAYLTDIERSPNTVKAYAHDLKDWFVFLDARSLNWREVRLEDLGEFVSWLRLPPAGRAGAVVQLPSAEHHCSAGTVNRKLAAISGLYTFHARHGVDLGDLVTELHPGRRRRSGWKPFLYHLSSGQPERRRTIKLRTPRQHPTILTAGQVQAILDACIHLRDRLLWALLWDTGIRIGEALGLRHEDVAAAEGELTVAPRSNDNRARAKSATPRTIPISPQLIRLYADYLHDEYGDLDSDYVFVNLWGEPFGHPWGYPAVYDLVLRLRRSTGIDFDPHWYRHTYATRLLRQNTPIEVVSTLLGHSSIATTMDIYGHLSVEDARRALEAAGFLTGQEVQW
>NZ_AP022614|5058706:5110212|5059515_5059986_-|WP_007172184.1|DBSCAN-SWA
MRITAAQRIHNENRIRAAMDRLLRGEISPGGNCDIKTLALSAGVDRTAFYGTRPYAHLRAEFEHRLQQLQQAGETPDPKTAQIERLKTEVEKLKNNLAHVNSTIQELTNFRSQALARIAAQHDEILRLRTANDPAAGITRLASNRPKYQQRVMGPC
>NZ_AP022614|5058706:5110212|5073796_5075410_+|WP_163670909.1|DBSCAN-SWA
MSQEELAAWVADEKPRISAHQFSLAGLPELVRFELLYALQRRDEAPPPLDPLQVRILISRLVGASSLRHADPEAVCESGGVQYNSAIKGLFRDLRRHLERAWTQYTGTDPYAGNVWRVELLDLQSNGSRRWPATKGTIDFGPIELGWLREVLKDWARNTRPYLQGLRQALRACHVASQTLVACGRADPASLGAGDFVLVEQAIVEQRRTDGSPHSASHRTQLLRLFCAVIEHGRANALMTDVPDPFRPPQRRHRVIEDANEEQLGKALPDMVIRQLDQHLDLLGPAGRHGSMSAPDLQAMHRTIYQILRDTGRRPGEIVSLKIGCLEVIDGQHNLIYDNHKAARLRRRLPITTDTAEIIAAWQRHRTQLPTAPATRQWLFPSPLLRSRQARGHLTASCVGVAFRTWTRSMIDGCTLRSALHQLIATLGYYSVTHKRKQQAIRAVGSLAIDASGNPSSFADPLAYERASVSVPFGNCTEPSNVKAGGGACPIRFQCAGCGFIARTRHIFPPSKSTSTRFRRTGRPPGQWRPLTTWSPT
>NZ_AP022614|5058706:5110212|5072467_5073232_+|WP_163670907.1|integrase|DBSCAN-SWA
MIEQAVANRLSEPRWLRFTPPGFDAGESGQFRMVRTRTLKARAEAVFPEAFTPEQAERVAACCRRPRERFMVALLRDGGLRIGEALGLRRSDLHLLPDSRRVGCTVLGAHVHVRHRANPNGALAKSRFPRTVPTSQAVLSTYADYQFERTEILGGDDCDMVFVNLYHEPLGVPMTYRAAKRFFERLATDCGFAVRPHMFRHTAATNWVRAGVDLDVVQRLLGHAALASTAVYLHARDEDKRRAVEAVAAGERFR
>NZ_AP022614|5058706:5110212|5083221_5083668_+|WP_007172201.1|DBSCAN-SWA
MYTQWIEQCTVQRVSLHEGLVVDLDDHNQLVISRPMRLTLPPAAGWPEEEVLIDPINLSAEERPLLDLAGAICTRAWCDDDGALHLCFSRGHRIDVDPDAAATSWELYGKCHGYMACLPRGRVRVIRHDLPVDENDLDATQSVAMAHQ
>NZ_AP022614|5058706:5110212|5106201_5106375_-|WP_007172215.1|DBSCAN-SWA
MPGTMLIAAGVTGKGRLAGRAAFVPFVDPAVGGIPPSAPPPSADIAAASAEAAQECA
>NZ_AP022614|5058706:5110212|5058706_5059339_-|WP_101930856.1|transposase|DBSCAN-SWA
MPIDVLAELLDHRSYSVTRRYYRIGEDRRRDAVDTVTTLSFDRHGNRIWRDAHALLDSERARHAIGEVAVPDGTCTEPTNVKAGGGACPIRFRCVGCDHFRTNIAFLPDLQAYLDDLLRTRERLAATIDGVDEWARADATPTEEEITRIRRLINRIKGDIAELDDTERAQINDAVAIVRRHRAAHTVPLGMPTLAATPPAPATPASEATA
>NZ_AP022614|5058706:5110212|5062180_5063905_-|WP_007172186.1|DBSCAN-SWA
MPTTVLDDPLRLACVFSDGSRAAFDLTGLPNPGLVRDLATGLVELIHPHGSVDTAGTVDQYVRGLHRMVRTLSDQGFTGGVGDLRRGQLAQFWMAGPNWLEALTRYLVEGYARSGGRLGEGVLELAAGRHFNIQRNRRPLPPYSEGAWQRLTMACRQQVDDSYAAHRRALASAAGGRHPGTGAWTHQNFCWLLSTLGPLGSSEAAEEIGMSINVFRHRGVIAVFHEAALAMFPHLEVVIAYRLLFGIYSGIVPDGIADLDIGDIDWAGDSTVLLSYIKRRTAAESATLPRPAVRLLEQWLAHSALLRSFVPPDERTTLWLGMSQPGYSRRLDDVNRSAIGRWMRRHGIVGDDGQPMKLHRSRIRTTHHAMRDKKSWTGNARATIDPNHTPAVEGDHYLSATTPGQRHAVETIIADAQHDILRRAHPPAVITEEDAAALAEGYPQLLAVMKLDEGVLAELVGGARDVFTAACADQLAGLHGPAGKPCPARPWVCLLCPLAVFAPRHAVNLLRLKAFFSRQWQQMPAAHFMTVFGPYAARIDQILDRFDPAELAVAAARVTDSDDEIPLRPEERTA
>NZ_AP022614|5058706:5110212|5072111_5072414_+|WP_163670906.1|DBSCAN-SWA
MNSFHAERAVSPLDGSEVWVVLDTGLVMHREASDFLRALHGAGRSIHTIRAYAGRVASFLGWCADQGVEWSSISLPGLARFKHFIEATRAGMGGCVRAQR
>NZ_AP022614|5058706:5110212|5108026_5109214_+|WP_033721567.1|DBSCAN-SWA
MRTWALASEPAIAAVEELPPGKYEGHDGAGMQELVLRRFLQSHSLGPRDVDGLLVCPSGMASGAGADIFVHERLNDVLGIRPRFCETVNVGGATYTIMLSRAALAISAGLANAVLCIGAGKFPKVGRGGGANAMARMISHPDFEYPYGSFIPALYALAATRHMAERGTSRDALAAVAVSSREWALRHPDALMRNAGPLTVEMVLASRPIAWPFNLLDCSVPCEGGAVFLVAHGDRAREITDQPAYVLGFGEHHDHGNITHTSDFATMGASVSARAAFEMADLSPSDVQVAELYDAFTINPILLLEETGLVAAAKGGHFFLDGRGAPGGDLPVNTYGGLLSFGHTGDASGMSMLIEAARQVMGKAADRQVSAEIALVHTYGGMMADHSTVLLGRTP
>NZ_AP022614|5058706:5110212|5059982_5062184_-|WP_007172185.1|DBSCAN-SWA
MTSTIATAAPGVQPRSPFTGADICRDAGLTLPGGTPRPVFDDDLWDFTDVVGLPVQMALYRRRFDFTTITDTRWRLVAKELILALLAPNHNAVVRLPRAYRTPLHLTSCYSRLYEAGKFFGWLDQRGITALTELDTHLCEEYLAFRRYVIDPDGVIVGEQSPGVRRAAAQMIVDLVDYRDLFTADRVPADLRPWGGATASAVAEMPSGRDGNKTPAVPAEVLQPMLAAALHLVQILGPHVVELNEQIRKIDRVWATGAPGLRHGSPAMVSDITMLLADHRATDTPLPMLEEHDVNRRLKAGWDANDPLLPVSTGTLARQAGYVQFWAKWMPTLRKPLIDTLNTVGVEKIFGRNAAEVPAADGATLLPWTLPVHRSEAVAMVGIARTAAIVVLAGASGMRASELMELRVGCRRVEEPISGLKCYRIASKIIKGQGLGGTDDEWVVIEPVHRAIELIEQLHDDPRDGVLLLSRFSFRVRYLWFRAWVNSPAGARLGLVPIPDEPVALRMLRRTVALEMAYRPGGVLAAKLHLKHIAAATTEGYAARPGGAQAELLAEVNKLEADHILKLVLAEFRNYQQGILPAGPGARSLTEFFATIDTDPNTKATAAPKIQRNDRDILNLLSKRATALHLGPANYCWFTDPSRALCLKLAGTLTADRPMIGMCDSARCPQATHHQHHRPVWAEHAERTKTFLGQLGKTRTAERARLQADYDRAVQVITSIDTATGTSAPEEQA
>NZ_AP022614|5058706:5110212|5092590_5093010_-|WP_007172563.1|DBSCAN-SWA
MKKMWIVLVIVAVVAVAGFCVLRLRTFFGVHDDQTMTSGIADEIKPFNPKRVVYQVYGPPGTVANINYLDINAQPQKASNVPLPWTLSVTSTLPSVSVNIVAQGDSNQIGCRIIVDEVVKDERSSQGMNAQTFCIVKSA
>NZ_AP022614|5058706:5110212|5084675_5087621_-|WP_040624282.1|DBSCAN-SWA
MLIIGMWVVSAAALAVLFPQLETVVRQQSVNLIPRDAPSLQTVDRMGAAFGEQGSKTTIFVAMEDPAGLTAPVRGRYNAMISRLRADSEHVRLVQDLLADPVTASQAVSQDGKAWYVPVGVAGTLGDLKAAESVQAVRTIAAQAFSGSPTDVRVTGPPATFRDQIASAEEDLVVISVATAGLIAMILLVVYRSVFTALLPLLVIGVSLAVGRGVLSALGESGMPVSQFTIAFMTVILLGAGTDYSVFLISRYHEQRRQNVPPDLSVINATATIGRVILASAATVAFAFLAMVFAKLSVFAALGPACAIAVFVGFAATVTLFPPVLALAAKRGIGEPKADRTRRYWNWIAVAVVRRPVPLLVASLALVLGLAAVALTMHISYDDRQGQPATTASNEGYHLLDRHFRKDVIITEFMLVESPTDMRTSKALADLDEMASRVSQLPGVTKVSGVTRPTGARLDQAQLSWQNGQIGNKMAGAVAKGDAHKDDLAKLTHGADQLAGGLAQLDTTLRTALTPLTGILTQAQSSGSQVQRFRPLLQQLSATAPAVDQAIRTGPGLRQQADQAQNAIAAIDPLVGALNTSPWCATTPECAQLRDQVQILVTLRHTGFFNQLANLGDLYQPGSDTAAGTVADVQNAITSLDKAFGALGDPADLAGNIRRLQSGISQLASGAQALATGVHTLADSNIEMLSGMSQIATQLQNSARTTAGSDNASGFYLPTNAFENRQFADVAKHFLSPDGKTARFAIESSYDPYSSDAMNLAHKITEIADAARPNTSLANATVSMAGFPAVNSDIQRLLSADFHQLAFATLVIVGLILVVLLRALVAPLYLLGTVVLNYGAALGLGTLVFQYGLGKEIAWPVPLLAFIILVAVGADYNMLLISRLREESTHNIRVGVLRTVANTGSVITSAGLIFAASMFGLIVGSIAIMIQAGFIIGCGLLLDTFVVRTLTVPAIATLLREASWWPQRKPLTHNGRPHRTT
>NZ_AP022614|5058706:5110212|5089456_5089621_+|WP_007172205.1|DBSCAN-SWA
MFSEAVYGDPLWFAWPNHMKIFCNNKGVVAKSTHVCNNYLPRGNVGLELELTPP
>NZ_AP022614|5058706:5110212|5088566_5089208_+|WP_007172204.1|DBSCAN-SWA
MERDTLEFPVDDDDDVDPRLLRSRTRLLDAATKLLSAGGIEAVTIDAVTKASKVARTTLYRHFSSSTQLLAATFERLLPQVHPAPETGSLRDQLIELLSRQATLFQEAPLHVTTLAWVALGRTPNGTQETHDRHALRTRIIDQYRQPFDALLQSPEARADLDDFDPELILCQLVGPVAFARLTGLRAIDRQDCERIVDDFLAAHRRKADEPAS
>NZ_AP022614|5058706:5110212|5104813_5106205_-|WP_033721564.1|DBSCAN-SWA
MSASVRIGAGAGYWGDMVDPAVELIEQGGVEFACFDLLAELTVALLTRAKMRDPGKGYVPDVEPILRQALPAARRNDVGIVTNGGGANPGAAALAAARVACDAGYPDTRIGTIEGDDLTGRIAEIRDSGWQFAHLESGEEDIDRIADRIVAVSAYTGSDGIIDALDGDADVVIGGRLADSALYCGPLMRHFGWIFERNPDLIGAALTVGHVLECAGIATGGMSSQWRLSRDPWRLGFPMAEMSADGTAVISKVPGSGGVLNEWTIKEHLLYEVHDPFCYLLPDGVVDMGGVEVKELGPDRVQLTGMTGRRRPDTLKVQIGYEDGYLAEGRTMIPWPDALEKADFCERLVRGRIKYLGVIPQEMRFDRVGWDALAGPVAPRPAPDAQPNEVELRMVAKCRTRSEAEVARRAMLLPATAGPVGTAFGAPLAVRKVIALWPTLVPREFVPQHVRVQAAKEMLDAHH

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_101930856.1|5058706_5059339_-|transposase	transposase	NA	NA	NA	NA
WP_007172184.1|5059515_5059986_-	hypothetical protein	NA	NA	NA	NA
WP_007172185.1|5059982_5062184_-	hypothetical protein	NA	NA	NA	NA
WP_007172186.1|5062180_5063905_-	hypothetical protein	NA	NA	NA	NA
WP_162839945.1|5063904_5065374_-|integrase	site-specific integrase	NA	NA	NA	NA
5065837:5065853	attL	NA	NA	NA	NA
WP_085270300.1|5069151_5070261_+|integrase	tyrosine-type recombinase/integrase	A0A220NQQ9	Corynebacterium_phage	2.3e-08	29.9
WP_163670906.1|5072111_5072414_+	hypothetical protein	NA	NA	NA	NA
WP_163670907.1|5072467_5073232_+|integrase	tyrosine-type recombinase/integrase	A0A0P0I3D2	Lactobacillus_phage	1.8e-07	27.8
WP_163670909.1|5073796_5075410_+	hypothetical protein	NA	NA	NA	NA
5073483:5073499	attR	NA	NA	NA	NA
WP_085271075.1|5075671_5076166_+	hypothetical protein	NA	NA	NA	NA
WP_007172194.1|5076781_5077222_+	hypothetical protein	NA	NA	NA	NA
WP_007172195.1|5077447_5077774_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_007172196.1|5078622_5079243_+	hypothetical protein	NA	NA	NA	NA
WP_040624304.1|5079243_5080278_-|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	7.0e-31	31.5
WP_033717415.1|5081506_5082106_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_007172200.1|5082534_5083146_+	TetR family transcriptional regulator	NA	NA	NA	NA
WP_007172201.1|5083221_5083668_+	hypothetical protein	NA	NA	NA	NA
WP_033717417.1|5083782_5084679_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_040624282.1|5084675_5087621_-	RND family transporter	NA	NA	NA	NA
WP_007172204.1|5088566_5089208_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_007172205.1|5089456_5089621_+	DUF5078 domain-containing protein	NA	NA	NA	NA
WP_007172562.1|5089660_5092594_-	MMPL family transporter	NA	NA	NA	NA
WP_007172563.1|5092590_5093010_-	hypothetical protein	NA	NA	NA	NA
WP_033721600.1|5093617_5094628_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_047324229.1|5098660_5099803_-	acyl-CoA dehydrogenase family protein	NA	NA	NA	NA
WP_007172209.1|5099879_5100536_-	transglutaminase family protein	NA	NA	NA	NA
WP_007172211.1|5103515_5103968_-	hypothetical protein	NA	NA	NA	NA
WP_007172212.1|5103982_5104495_-	MaoC family dehydratase N-terminal domain-containing protein	NA	NA	NA	NA
WP_007172213.1|5104491_5104827_-	hypothetical protein	NA	NA	NA	NA
WP_033721564.1|5104813_5106205_-	DUF1446 domain-containing protein	NA	NA	NA	NA
WP_007172215.1|5106201_5106375_-	hypothetical protein	NA	NA	NA	NA
WP_007172216.1|5106831_5107986_+	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_033721567.1|5108026_5109214_+	thiolase family protein	NA	NA	NA	NA
WP_033721568.1|5109225_5109615_+	Zn-ribbon domain-containing OB-fold protein	NA	NA	NA	NA
WP_157679851.1|5109666_5110212_+|transposase	transposase	A0A2P1JQX9	Mycobacterium_phage	6.7e-41	61.8

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NZ_AP022614|5192721:5295930|DBSCAN-SWA
GTTGGCATCGTCGCGTCGGGTGAAGAAGGGGCCGGGACGTCGTCCGCAGTCGGCCAAGCGTCAGCGGTTCATGGAGTTGCGGGCTCGCGGGTGGAGCGTGCGGGCCGCGGCCCGCGAAGTCGGTGTGTCCCGGTCCGCTGCGACGAACTGGACACGCGGTTACAAGACCTACCGCAACGGCGTCGCGGTCGGGTTCGTCCCGCCGCTAGATCGACTAGCGGTCCGCCAGATCAGCACGCGATACCTGTCCCAGGACGAGCGCATCGAGATCGCCGATCTGCATCACTCAGGGCTGAGGGTGCGGACGATCGCCACCCGACTCGGTCGAGCGCCGTCGACGATTTCGAGGGAGCTACGGCGCAACGCACCAGCCGGCCGCGGATATCAGCCCTTCGATGCCCACCGGCGAGCCACCGCGCGACGAGCACGTCACCACCGCCGTCGGGTCGACACCAACGACCAGCTCGGTAACGCGGTCGCCGAGCTGCTTCTTCAGCGTTGGAGCCCCCAACAGATCAGCCGTCACCTCCGCCACCGCTTCCCCGATGATTCATCGATGTGGTTATGCCACGAAAGCATCTATCAAGCTGTCTATCAACCGAATTCACGTTTCATGCGGCCCTCGCGATTAGCGCCGCACCGACGCTCACCGCTGCGCACCGGTCGAGATCACCGCCGAGCGCATCACCGCCAGAGTTGCCGGCGGCCGCGGTTCCAGCAGCCGATGCTCACCATCCACGACCGGTCCTTCTCGGCTGTCGACCGGTCTGAAGCCGGCCACTGGGAAGGCGACCTTATCATCGGTAATAACCACCTCTCGGCGATCGGCACTCTGGTCGAACGCCAGACCCGGATGCTGCGGTTGGTGCATCTGCCTCGCAGTGACGCCGACTCCCTGCACGCGGCCTTGGTGGCCCGCATGAAGGATCTGCCACCCACGCTGATGCGGTCGATCACCTGGGACCAGGGCACCGAGATGGCGCGCCACCTTGCCACCACCGACAAGCTCGGCGCGCCCGTCTACTTCTGCGACTCCAGATCACCCTGGCAACGCGGCACGAACGAGAACACCAACGGACTGCTGCGCGACTACTTCCCGAAGGGCGTCACCCTCATCAGCCACCCGCCGGAGCAGTTGTTGGCCGTCGAACACGAACTCAACCATCGCCCCCGCATGGTCCTCCAAGACCGTTGCCCCGCCGATCTATTCGCTGCCCTGTTAGTCTCGAGTGATCCGTCGGTGTTGCGACGTTGAGTAGAACCCACCCCGTCGAAAAGGGGTCAATTTTCGGCCGCCGTTGACAGCGGTTGTGCTAAGTAGTTGGGTGAGGGCGAATCGCTCTACACCCGAGTCGATTCCAGCCAATCTTTGACGTCATCCAGTAACCATCGACGGTGCCGATCGCTAAGCCTGAGGTGATGTGGACCAGGCGCATCAATCCCACGTTCCCGCCTGGCCGCCCATTCATGCAGCGTTGAGACCGGAACTCCGGTCATCGCTCGAACTTCATGAGCGGTGAGCATGACCGACGCATTTTCTATCGTCATCGTCTCCAACCCCAGTTGCGTCCAGCAGAGTGGTGTACGAGCCGGTGATGACCGGCGTGTCGTAGCCGGATGAATGAAGGTCATCGCGTGATTCTTCGAGGGACCGACCAAAGTCACTCGAGCAAAGGAATCAACGCGATGACCATTGCCCACGATATCGACCTGTCTGCCGTGCTGGCCGAACGACTCACCACCACGCACCCTGATGTGCTGCGCGAGTTGTTGGCCGCCTTCATTCACGCCCTGATGGGCGCCGAAGCCGACGCGGTGTGCGGTGCCGGCTACGGCCAGCGCAGCAGCGAGCGCACCAATTCCCGCAACGGGTATCGGCACCGCGAGTTTGACACCCGCGCAGGCACATTGGATCTGGCGATTCCCAAGCTAAGGCAAGGTTCGTACTTCCCGGACTGGCTGCTGGAACGGCGCAAACGCGCCGAGCGGGCCCTGACCACGGTGGTGGCTACCTGCTACCTGCTGGGCGTTTCGACGCGGCGGATGGACAAACTCGTCGAGACTCTGGGCATCACCAGCTTGTCGAAGTCCCAGGTCAGCGTGATGGCCAAAGAGCTCGACGCCGCGGTCGAGGCGTTCCGGACCCGGCCACTGGATGCAGGCCCGTACACGTTCATGGCTGCTGACGCCCTGGTGCTCAAGGTTCGCGAAGCAGGCCGGGTGGTCAACGTGCACGCGCTGATCGCCACCGGGGTCAACGCCGAGGGCTACCGCGAAATCCTGGGCATCGACGTCACCACCGCCGAGGACGGGGCCGGCTGGCTGACCTTCCTGCGGTCGCTGACCGCCCGCGGCCTATCAGGGGTCCGTCTGGTCACTTCCGACGCCCACGCCGGTCTGGTGGCCGCGATCGGCGCCACCCTGCCTGGGGCATCGTGGCAACGGTGTCGCACCCACTACGCCACCAACCTGATGGCCATCACTCCGAAATCATCGTGGCCGTGGGTACGCACACTACTGCATTCGGTCTTCGATCAACCTGACGCCGGTTCCGTTGCAGCCCAATATGACCGCATCATCGACGCACTGGCCGACAAGCTCCCCAAGGTCGCCGACCACCTCGAAGACGCCCGCGCCGACCTGCTCGCCTTCACCGCCTTCCCCAAACAAATTTGGCGGCAGATCTGGTCCAACAACCCACAAGAACGACTCAACAAGGAAATCCGCCGGCGCACCGACGTCGTCGGAATCTTCCCCGACCGCAACGCCCTAATCCGCCTCGTCGGCGCGGTGCTGGCCGAACAACACGACGAATGGGCCGAATCCCGCCGCTACCTCGGCCTCGACGTCCTCAGCAAATCCCGCGCCGACCACACGCCATCAACAGAACAGGAGGACACCCCGGCGGCACTGACCGCCTAAACCACCAAGTCGAAGAATCACACGACGACGTCGTACACCACGTCCCTGGACTTGACCCCAACCCCGTCTCCCGCCGTTGGTACTGGCCGGCAGGTCATACCGAGATCATGAGGCATAGTTTTCGATTCCCGCTACCAGCAGTGCGACATTCGATCGGAAATGCACCGTCGAGTGCGGTCAGGGGGTCGAATCTGCGAGACCGGCTTTAGGAGAGCGGTCAAGCCCTTCTGGTTGAGGTCCAGAAGGGGTGTCTGAGCTGGTCATATAGCGCCATCGCACACCAAGCGAAACCACCGCGTGCCGACCAGTGCAGATAGCGGGTTTCAGGCTGCTGTGGTACGGGTCTCGTTGGCATAAGTGTGTCGTAGCGCGTGAACGAGCGCACCCGACCGTTTCCCGGATCGGACAGGTGGTTGTGGTGAGTGGTGCGGATCGGTGCGGATGTGTTGCATTGGTAGGCAGTCGATTTGGCGACAAAGGGTGCGGACAAATGGGGACACAGATGATGTTGGTCAGGATGGTAGAGCACGACGATGGGTGCGTCCTATGGTTCCCACGTGGTGAACATCAATTCGAAATCGGCAGCGCGCAAGCGTGTCCGGGAGGCGCAGAACAAGGCCAACGAGGCACGTCTGGAGCGTGAGCGTCAAAATGTCGATGACGCTGCGTCGTTCCTCGTCGAGCTTGGGCGGCTGGCCGCCGTCGACGAGTGGGAGCGCAACCGTATCCTCGAGATACACGCAGAGGGAGAGCGGCGCCGTCACGAACACCGCCAGGCCGGCGCGACAGCGTTGGCCCGGATGCAAGGCCGCGGTGAAAGCCTCACTGCGATCGCTGAACTGGCGGGAGTCAAAGTCGGTGAGGTAGCACACATCTCGGCTGGGCTCAATCCGGGACGTGTGTCGCCAAGTGACTCATCCTGTGCATCAACGGGTTTCGGATCGCGGAGCGCATGACCCGATTTGACTCTGCGGGCGGACTCGCCGGTCTCGGCTCCGACGACCAGCACCGCATCGCTGATACCGCGCACAATGTCCCCACCAAGGACCTCGACGAGGTATTGCGGTGTATTGCCGCCAATCGGGCAGCTGATGCGACGCCGGGGCGCCAGCCCAACCGCTTCGGCAATTCTCGACGCGGGATTGTCACGCGGAATCATCAGAATGCCCGGTGTCGCCACCGTATCGATCCGATGCCCGATCGCAGCGCCCGCGTCTTGCAATGCTCGACGCGCGGCTTCGCAAGCCAAATCGATGGGATCGACGACGCTGTCGCCGCGGTGCGTGATCTCACCGACCGCGACGACAACGGGAGTGCGGGGCGGAATCGCCAACGGTCAGGTCACGTTCATCGTCGGCACCTTTGTTGCGACATATTTGCGATATTGTCACATAAGTAGCCATGCGACAACCGGTTGGGTCGTTAATTCACGATCGGTCCGAGGCTGCATACTTGCTTCGTGACGAAGAAATCGTTGCGCTGGGGCACGGCACCTCCCACGACCCGCGACGTCGCCCGAGACCTCCTGCTCGATGCCGCCGAAGCGTGCCTGGAGGGCAAGGGGCTGCCGGGCACCACCATGGAGGACATCGCCAGACAGGCGGGGGTGTCGCGCGCCACGGTGTACCGCTACTTTCCAAGTCGTGAATCCGTCGTTTCCGGTGTCATCCTGCGTGCGGCCGAACGCTACCTAGACCGCATGCGTCGACGGATCGCAGTACATCGCGATTTGGGCACGGCAATACTCGATTTCGTCGAGGTCACGGTACGCGCCGCTCATCGCGAGCCGACAATCGGATTGCTGTTCGGCAGTGACGAGGAACTCGCCGGCGTGGGGTTGGCCAAGGGAACGTCGGTGGCTTTGTTTGAACTCGTGGCCGAGTTCCTTCGACCTGTCTTCGCTGCGCACTGGGACCAACTCGAGCCCGGGGTGTCGGTCGACGATGCCGCCGAATGGATCCTGCGAACCGTCCTCAGCCTGCTGTCGGTCCGCGGCCCCAGACACCGCAGCCCCGAAGGCCTCGATGCCTTTTTACGCCGATTCCTGCTTCCAGCTCTGCTCACCAACACCCAGCCTTGCGTCGATGCAACAAGTGCAGAGTAGTGTCTCAAACCATCGCATCGATATCCGTGGATGAGAAGGGGCGCTAACCATGGAGTTCGCGCAGTTCAATCAGCAGATCGCCAAGGAATTGCAGAACGCGGCGGCAACCACGGGAGGACTCTCCAAATACCTGGATTTTCGCCACACCGAGTTCGCCGCCGGGCGGCTGGTTGTGCAGATGGATGCTCGGGACGACCTTTTGACTCCGTTCGGCAATCTGCACGGCGGATGCCTGTCAGCAATGGTCGACCACTGCTTGGGCGTGGTGTTTTACCCGGTGATCCCCGCTGGATCGTGGGTCGCCACAACCGAATTCAAGCTGAACTTGCTGCAGCCCGTGTCAAGCGGAGTATGCGTCGCCGTCACCGAGATCATCGCGCTGGGCAAGCGCAGCGGTGTCGCCAGAATCGACATCACCAACGACGGGCGCGCGGTATGTGCCGCCCAAGGAACAGTGACCGTCGTTAGCCCTAGGGGGAATTCCTCGTGATGAAAAGGACCGATGGTATTGTCGTCCGACTTCACAACGGCGAGCGCACCCGATGACCGTTACGCTCGAGCGATTCCGCACCACAGACGGCGTCACCCTCACGGCGGATTGCTACCGGCACGACGCTGCCCGCGCCGTTGTGCTGCTCCTGCACGGCGGTGGTCAAAACCGACACGCCTGGGCGACCACAGCGCGCCGCTTGCACGCTCGTGGGTACACGGTCGTCGCGTATGACGCCCGAGGTCACGGCGACAGCGCGTGGGACCCTACCGGAAGATACGACCTCGGACGGCTAGCGTCCGATCTGCTGGCCGTGCGTGAACACGCGAGCACCGACCGCCCGCCGGCCGTCGTCGGCGCATCCTTGGGCGGCATGACCGTCCTGGGCACGCACTTGCTGGCGCCCGCCGACCTGTGGGGAGCCGTCGTCCTGGTCGACATCACTCCGCGAATGGAGTTTCACGGAGCACGCCGCGTCGTGTCGTTCATGGCCGCCCATCCTGACGGGTTCAGCACGCTCGACGACGCCGCGGACGTCATTGCCGAATACAACAGACATCGCACTCGGCCCAAGAACCCGGACGGACTCCGTAAAGTCTTGCGGCAACGCGACGATGGTCGGTGGATCTGGCGATGGGATCCGGCCTTCATCACTTCCAACTTCCAGTTTCTGCAAGGTGACCCCGCGACTGGTGCCGAAAAGTTCGACGCGATCAGCGAACTGCTTGTTGAAGGGGCCCGCCGCGTGCAGGCACCCACTCTTCTGGTGCGCGGCGTCCTTTCAGATGTGACATCGCAGCAGTCGGTCGACGAATTCCTCAAGGTCGTACCGCACGCCCAAGCGGTGGACGTCTCCGGCACCGGCCACATGGTCGCAGGCGACGACAACGATGCCTTCACCGCAGCCGTCGCCGGATTTCTCGACCGCACGATAAGCACTTCAGCGTGAAAAGCTCTGGGCTATCTGGCGCAGCCCGGGCTGGCCGCGCCAAAATCATGGCCGAGCTCGGCATCAAGGGGATCAGTCCGCGGAGGTTTAAGACCACCACGGTGGTCGATCCGGCCTCGTTTCCGCCGGATCTGATCGGCCAGCGCTTTGATAAGGGCCGACTCGACGCGGTGTGGTCCTCGGATATCGAGCGCCGTGAGGCGCTGTTCAACCGAACGGAGGTGAGAGACCACCGTCGCCGAGCCATCGCAGTGGCCCGGTAGAAGCTGGGGGCAGCCTGATCTAAAGAGACTTTGGTGAGGGTGGGAAGCAGCCCCGACAACGCCGGGACGGCCTGGTACTGCCAGACGGGTCGGGTCCGGCTAGCGAGACGGGAAGGTGTACGCGAGGAACCAGCGGCTGAACGCCTCTTAAGAGAAGACCACCAGCTCCAACCTGGCGGATGCGGGCTGGGCAGCGACGCGCACCCGCCCTGAGGGCGGGGAACTCGTGGGCCGGTTGATGTCGCCGGTTCGGGAGGTCACGGTGAAGGACTGCGGCGTAGCCGTGACGAGGTCGCAGGGGCATAGCTGGACACCTCACCCGTCAAACGGTTGACAGTGAACACGGGAACCACCGCGCCGGTCCCCGGTCAGATCCGGCAGCCAGCCGGGCTGGAGGGGTAGGCAGTCGTCGGCTGATGCCGGTGTGGTGGGGCGGAGGAGCCGTAGTAGTCCGAGGCCGGGAAAGCCGGTCGCATGGCAAAGGGCTCCAGCGGGTTCGCGGCGAGTACGCAGACTGTGGAGGTCACTTGTGAATACGAGTGCTTTGTGGCCCGACCCGGACACGGCCGAGCTGCGGGTACGCAGGATGCAACGCAAACTGCACCATTGGGCGGTTGATGAAAGCGACCGCTGTTTCGATGATTTGTACAACCTCGTTTATGACCCCGCATTCCTCACCCTCGCGTGGGAGCGGGTGCGGACGAACAAGGGTGCGCGCTCAGCCGGTGCCGATGGGACCGCACCGCGGTCTGTCGGTGCGGCAGAGGCGGTCGGACTGCTTCAGCGGCTCCGCGAGGAACTCAAGGAGCGGATATTCCGGCCGGATCCGGTGCGGGAGGTGATGATCCCGAAGGCGAACGGCAAGCTCCGCCGCCTGGGTATCGCGACCGTCGCCGACCGGGTCGTGCAAGCTTCGCTGAAGCTGGTGCTGGAGCCCATTTTCGAGGCGGACTTTCATCCGTGCGCATATGGGTTCCGGCCGGGCAGGCGAGCCCAGGACGCCATCGCTGAGATCCATCACCTCGCCAGCGGCTCACGGGCCTATCACTGGGTTTTCGAGGGAGACATCACGGCGTGCTTCGATGAAATCTCGCATTCGGCCCTTATGGGCCGGGTGCGGCGACGTGTCGGGGACAAACGCGTTCTGGCCCTGGTGAAGTCGTTCCTCAAAGCCGGGATTCTCTCGAAAGATCTCGGCTACCGGGACACCATCACCGGCACTCCGCAAGGCGGAATCCTCTCACCACTGCTCAGCAATGTCGCCCTGTCCGTTCTCGACGAGCACTTCGCCGCGAAGTGGAAGGCGCTCGGCCCGGAATGGACACGTGCCAAGCATCGACGCGCCGGAGTTCCGACCATGAAAATCGTCCGCTACGCAGACGATTTCTGTGTCATGGTCCACGGCACTCGCGCTGATGCCGAAGCGCTTTGGGACGAGATCGCAGCAGTGCTCGCGCCGATGGGCCTGCGCCTGTCGGTCGAGAAGAGCAGGATCTGCCACGTCGACGAGGGGTTCGAGTTCCTCGGCTTCCGCATCCAACGGCAGATCAAAAGGGGCACGACCAAGCACTACGTCTACACCTGGCCGTCGAAGAAGGCACTTATGTCCATCACCGACAAAGTCAGGAATCTGACGCGGCGACACAAACATCGAACGCTCGCTGATCTGCTGCGCCAACTCAACCCCGTCCTGCGGGGATGGTGCAATTACTTCCAGCACGGGGTGTCCAAACGCACCTTCGACTACCTCGACCACTTCACATGGTGGCGGGTGGTGACTTGGATGCGCAAACGGCACCACGGGCTGGCGTGGGGCGTCTTCCATCGACGGTTCCTGCCCAATTGGCAAATCCGCGAAGGCAAGACGGCGATGTTTCGGCCGCAGAAGGTAGAGGTCACCCGATACCGCTACCGGGGCACGAAAATCATCACCCCTTGGACAGCGAGGCCGACGGACATCACTGCACCAGTGGCCTGAATCCGTGGAGAGCCCGTTGCGGAGAAATTCGCTCGGCGGGTTCGGAGGGCGGGCCGGGGAAACGGATCGGTAGAAATGCCGACACCGCGCCCCGGTCCGACCCCTACACCTATCTGGGCTGCGGGGAGGGCGACATGTTCTTGTGCGCGATCCGCGACGAGCACTCGCGGCGGGCACTGGGTTGGGCTGTGGATGATCACATGCGCACCGAGTTGGTCACCGTGGCCGTGCAGCGGGGGGTGTTCGCGCGCGGTGGGCGCTGCGCGGGTAATGCTGGGACAACGTCGGCGCCGAGTCGCTGTGGTCGAGTTTCAAACAGGAATGCTACTACCGGCACACCCTACGCGACCAAAGCGGAATTGATTGCAGGAGTTGACAATTGGATGAACTTCTACAATAATCAACCAAGGCATTAAGCGATCGGGACGCGCTCACCTATCGACTACGAGCGGACGCTGAACCCTGTCGCGGAAGCAAGTTATCCGTGTCCATTTTTTCAGGGGAACCCCAGACTTCGATCGCGACGTTGGCATCAGCTCGAAGCGTGGCGGTCGCCAAGCCGATGTCGCGAGTTCCACCGGATGATGACAGTGCCATGGTGAGAAGTAGCGGAACCCGGACAGCCAAACCGGCGAAGTGCATTGTTGTCGGCGTGGTCCTCGATAGCCCCGACGGAACACTTGTGCAAGACGCATATCCTGCTCACCATGCCAACAGAGTCCGTTCGCCTCTCGTTTCGCCGGCATATGCGTGAGCAAGTCTTGAGGGCTGCCCGGACCCTCACTATCGAGAAGGGCTGGGATCGCGTTCGCATGGGTGAAGTCGCAGAGCTTGTCGGCGTGTCCCGCCCGACGCTCTACAAGGAGTTCACCGATAAGCAGGGACTGGGCGACGCGCTGGTTGTGGCCGAAGGCGAACGCTTCTTGAATGGCATTCACGCAGTTTTGGCACAACACGCCGGAGACGTCGGCGGGGGCATCACCGCTGCGGTGTCGTACACACTGAAGGAAGCGGAAGCGAGCCCGCTCTTGAAGGCGGTGCTGACATCGAACCGGCCTACGGACAGGACGGTCGCTGAGTCAACCGGTATGTTGCCGCTCCTGCCGACCTCTGCGTCGCTACTGGAGCTGTCCTCGGCAGCCCTCGTGACCTGGTTCAACGAGCACTTTTCAGGCCTGGACGCCAATGACGTCAATGATGTCGCCGATGCACTGGTAAGGCTGACGGTGAGTCACGTCGTGCTTCCGACCGCCGACGCCGAGACGACCGGGGAGCGCATCTCGCGGATCGCACTTCGCTATTTGGGCGTTCATTCCTCCGCAGGCGAGGCGCGTTAACACTAAGGATTTTATGTTCAAATGTTGACTCTGAAGGAATAATTGTAAACACTTGGAGTGGGGCCGCACGAACCTTAGGAGATTCTCATGATTGCCAGCACGACGTCCGCACTGAAAACGTCGGCGGAGCGGCGTTCAGCACGTCCATATGATTCTGCCGACTTGTCCTCGACTGCATTTTGGGCCGGCACCGCCGCCGACCGGGAGAAGACATACGCCGAACTGCGCAAACGTGCTCCCATCAGCTGGCACCCGCGAGTCGAGCACACCATGATCGACGACGGGAACGACCGGGGCTTTTGGGCTGTGGTTACGCATCCGTTGCTTGTCGAGGCGACCCGGCGACACGACGATTTCCTGTCAGGTCAGGGCATTGTCATGGAGTCGATCCCGCAGGAATTGCTCGACACCGCTCAAGGCTTCATTGCGATGGATCCGCCGCGTCATACCAAGATTCGACGATTGCTGGCATCCGCATTCACGCCGAAGCAGATGCGACTGATCCACCATCAGATCGAGGCCAACGCGAAGCGCGTCGTCGACGACCTGGCTCCACAGGGCAAGGCCGACTTCGTCGACGAATGCGCGGCGTTGCTGCCGATGCACAACATCTTCGACATGATGGGCGTGCCGGACTCGATGCGCCGCGACATCGCGTGGGAATCACGGTATGCCGGTGGGTGGAGCGACCCCGAGGTGATGGGCGACGACCCAGTCATACCTCGCCTTTTCCAAGCGATGGGATTCCTAGGCGACGGCGCCCGCGAAATCATCGCTGCACGTCGCCGGCAGCCCGAAGACGACCTCATGACGAACCTCGTTCAGGCTGAAGTGGACGGTGAAAAACTCACCGAAGATGAGATCGTCTCGTTTTTCATACTTCTCACGATCGCTGGGAACGACACCACGCGCCAAAGCACCAGTCATGCGATGAAAGCCTTGACCGACTTTCCCGATCAACGAGCGTGGCTGATGGAGGATTTCGACGGACGAATCAAAGGAGCGGTCGAAGAGTTCGTCCGGTGGGCCACCCCGATCATGACCTTCCGCCGAACGGCAGCTCGCGACTGCGACCTGGGCGGACAACAGATCACCGAAGGTGACAAGGTCGTACTTTTTTACAGCTCGGCCAACTGGGACACCACAGTGTTCACCAACCCGGAAAAGTTCGATTTGTCACGGGACCCCAACCCGCACGTGAGCTTCGGAGGTGGAGGTATCCACCACTGCTTGGGCAATCAGCTGGCGCGGCAGCAACTCGCCGCGCTCTTCCGGGAATTGCTGCACCGCCTGCCTGATATTGAAGTCTGCGGGCCACCCAGCTATACCGTTAGCACTTTCTTCCACGGGGTGAATCATCTTCCCGTCCGCTTCACCCCGACTACGTGAGGCAGCGTGGCATGAAAATCACAGTCGACCGCGATCGATGCTCGTCAATCGGGATGTGTGAAGGCCTGGCTCCCGACTTCTTCGAGGTCAGTAACGATGGGAAACTCCACATCCTGAATCCTGGGCCACCCGAATGTCACAGGGCACTGATCGAAGATGCCGTGGCGAGTTGCCCCACAGGCGCGCTCGCGTTGCACGATTGACAGACTGGCAGCAGCGAGATCCGGTGCAGCTGTTCGGCACTGGCTTCCGGCCGGTCCACGATGACTGCTCCTCGTCCAACGGGCTCGCCGACATCGCTCAGGAGCACAACACAACGCAATGGAGCCGCAGTAGTGAGTACCTTTGGACTCTCTGTCCTAGCCCCTGACCTTGCCGCGATGAAGGTCACCGCCACCGCGGCCGACCAGGCCGGGTTCGACGCGGTGTGGGCATCGGAGTTCTATACCCGGTCGGGATCCATCTCGATGGCGGCAATGGCCACCTCGACTGACAGGTGTCGCATCGGGTCGTCGATTCTCTACGGCGTCGGACGCAGCCCGCTGGTCTTGGCGACCGAGGCGCGCGATCTCGACGAACTGTCCGGCGGTCGCATCGTGCTCGGCATCGGCAACGGCACCAAACGGATGATGAGCAACTGGCACAGCGTCGCCGATACCAGCGCCCCCGCCCTGCGCGTCGAGGAACTCGTACCCCTTATTCGGCGCATCTGGAACCTGCACGAGGGACCAGTCCGCCACGAAGGCCGCTTCTACCAGATGAATCTCATCCCCAGCGGCCCGGTAGACCCGCCTGCGCGCGATATTCCGATCATCACCGCCGCGGTGCGCCCGCGGATGTGCGAAGCCGCCGGCCGGGTCGCTGACGGGCTGGCCGGGCATCCGCTCTTCACGACCGCCTACGTGGAGGAAGTCGTGCGGCCCGCGGTGGCCAAGGGCGCCGCACGCACCGGGCGCGATCCCGACGACGTCGAGATTGTGTCAATGGTCATGTGCTCCATCCACGACGACCCGGAAATCGCCCGTCGCGAGGTCGCGCAACAGATCGCGTTCTACGCATCAGTCAGAACCTACCAACCGCTGCTCGACTTCTGCGGATTCGCCAAACAGGGTGCCGTTATCCGAGAAGCCTTCGCACGCGGTGACTTTGCGGCCATGTTCGACGCGGTGACGGACGACATGATCGACGTGATGGGCGTCGCTGGCACCGCCAGCGAGGTGCGCGCCGGGCTGCGCCGCTACGAGGGGGTACTCGACCACATCATGCTCTACCCGCCGTCGGTGGGTATCGCACCTGAGCGGGTCGGCCAAAACCTCGGTGAGATGATCAAGCACTGCGCCCCCGGCCAGTAACATCCCGGTTCATGTAGGTGCGCCAGCGTCTGTGTCGACGACAACCCGCGGCGGTGAATGAGTCTCCCGTCTAATTCGAAATGACCGGTTCATCGACGGTGTGCTCCTGCCGGTACCGTAGGGATCGCCTTCGACGACGAGTTCGTAAGCCACCTAGTGCCAGTGCTTCTCTGCTCGCGCTCACCGTTGATGCTAGACGCGGCTCCCGATTCGCTGGGCGCCATCGGAGTCGAAGAGTTCTTTGGCCCAGCGTTCGAGGACTTCGGTGCTGTCCCAGTCGTCGGGGTGGAAGCCGGCGCGGGTGTAGGAACGGAAGCGCTGCACCGCGTCCGGGCTGAACAGTGGGGAACGACGGAAGGCTCGAAGGCTGCGCAGTAAGCGCAGTGGGTTGTAGGCTGCGCGGTCACCCGCCAGAGAGCGAGTGGTCTGGATGACCAACTCGGTGAACAAGATGACTGTGGCAATCCGCATTCCCCAGACCCTGGTGCGTTCGGTTCCACCGACCGTCTCGAAGACGTCGAAAGCGACGGCCTTGTGCTCGGATTCTTCTAAAGCGTGCCAGAGCAGAATCGGCCGGACCTCGGTGTCGCCGATCAGCTCTTGTGCCTCGTCGCTGGTCAGAATGATTTCGGCGAACGTCGCCGTGTAGTGCTCAAGGGCAGCCGTCACGGCCAGGCGCATCTTCGGAGAGAATCGCTTCTCGAGCCGGTCAACCAACTTCTTGATGTGCCGATCGATCCCGTCGGTCGGATAGCCCATCGCTTGGAGCCGCTCGTTAAGCAGCCGATGCTGGTGCCGGTGGGTGGCCTCCTGCGCGATGAATCCCTTGACCGCCTCTTGGAGGTCGGGGTCGCTGACCTGGTCACGGTACTGGCGCACCGATCGGATGAAGAAGTCTTCGCCCTCGGGGAACGTTGCCGACAAGGTAGAGACAAAGTGGCTCATCACCAAGTCGCCGTCGACGAAGTGCTGGCGACTGGTCCCAGCAGGCATTGCGAAACGGACACGGCGAGCCTTTGGCAGCACCCTCTTTGCTGGCCGTGTGGGCGACTCACTGGTCATGTGCTACTCCCATCTCCAAGCGGACCTCAATAATCTGACTTTATACCTAGTCAGATTTAGATGACAAACTGTGTCTATGCGTTCAGTCCGGGTGTATCGCGGAGTGTCTGCAGAGCAGCGCCATCAGCACCGGCGTACACGTCTCATCGACGCCGCTATCGAGCTGATCGGTACCCGAGGCGTGGCCGCCACCACCGTGACTGCCGTCTGCGCCGAGTCACGTGTCACCTCGCGTTACTTCTACCAGCATTTCTCCGACCGCGACGCGCTCTTGCGGGCCGTCTACCAGCAGCTCTATGCCACCTTCCAAGACGTAATAGTCCAAGCGATCCCAGACGCCGGCGCGCCACCCGACGTGTTGGCGTATGCCCCCATCCGCGCACTGGTCAACATGATCGAAGACGATCCTCGGCTGGCCCGCATTTTGTTCGTTGAATCCGCAACGGAGCCACTCCTTCGCGAGTTGCGGAGCCAATTGATGGCCGGTTTCGCCGACCTCGTGCTGCGCGAGGCCAGACTTCACCTGGATATCGCCGACTCTGCGGTGGGCGTCGCGCATCTGGCTTCAACCCTCGGTGTCGGAGGACTCTTCGAGGTTCTGCGCCGCTGGCTGGACGGCGAACTGGACTTCAGTACTGATGAACTCGTCCAACACTGCGCAGGTTTCCTGGGCAGCCTCGGCACCTACGTGCTGCTGCAGAACATAGGCGAGGCGCCGGTTCCTGAATCCGGGGCATCGGCAAACGCTCTATCGGCTCGCGGCCACGCCCGGCGATGCTGAGTGCGTGTCCGGTTTGACGCCCACGATCAGGACGGTAGCGTCCCGGGCACGTCATCGACGCTGAGCGCGTGCACCAGATAACGTTCAGCTAGGGTTTCGGCGAGCCGACTGGTGTGTTCGACGATCTCCTCCTGACTTACGTCGAGCAAGCCGGCATGCCAGGCGGTGATCAGCTCGACGAAGCCCCCAACCGCCACCAAGGTGTCCATGCGGAGCGCGGTTTCATCGGCATCCGGTCTCAGATGGGGCTTGCTCGCCGCGACCACGAGGTGCGTCGCCTCTTGCAGGGCAACAGCGCGCCGGTCTTGCAGCGGTGAGCTGCCCACGTGCTGGGTCAGCAAGATCTTTGCCCTGCCGGGATCTTGTGTGATGCGGTCGACCACCATAGAGATGGTCATGCGAATAGTCTCGAGGGGCGGCTGCCCGACGCGTTCTGCGAGGGTCGCGGAAACCTCACCGAGCATCTCGTTCCGTACCCCGTCCCAGGCGGCAACCAGCAACTCGTCGCGGGTCTTGAAGTCTTCATAGAAGTAGCGGTCGTTCAGGCTGGTCCGGGAGCAAACGCCCCTCATGGTGACTGCGGCCCAACCGCTTTCGCTCCAGATCTCGGTCGCGGCATCGATCAGACGCTGCCGACGTTCCGCGCGGCGTTCCGCGCCGGTACGCCCGCCCCATCGTTTCGCCTTCGTCCGCACATTTCCATCTTGACAAAGCAACGTAGGTCACACCAAACTGACGGCATGTGCCCACAATGGTGGCTGGTGCCACCAGTTGCTTTCGAGGCAGCGACGGAATCAACCGTCAGATCGCAGCAACGGCGGATACTCCGATGAGGCTGCTGCCGTTTGGGAATCCCCCCCGCCGGAGTGACCGTGCCGACGCGGTGATCACCGGTGCAGGCAGCGGCATTGGCCGCGCATTTGCCGTCGAGCTGGCGCGCCGGGGCGGCCGTGTGGTGTGCGCCGACATCGACGGCATTCGCGCCAAGGAGACAGCGGACCTGATCTCCAAGCTGGGCGGTCATGGCATCGGCGTTGTTTGCGACGTCTCAGACGAGCATCAGGTCCGGGATCTTGCCGATTCGGCCGAGAAGTGGTTCGGCGGCGCTCCCGGACTGGTGATCAACAATGCCGGAATTGGCGCTGGAGGCAACGTCGTCGGTGCGACATCCACGAGCGATTGGTCCGCGACGTTGTCGGTCAATCTGTGGGGAGTCATCCACGGCTGCGAAGTCTTTGTCCCGCGGCTCCGGGAACGTGGATTCGGAGGGCTCATCAACGTCGCGTCGGCGGCAAGCTTCGGTGCGGCCCCCCGCATGGCCGCCTACAACGTGAGCAAAGCGGGCGTACTCGCGCTGTCCGAAACCTTGGCAGCCGAGCTCAGCGGAACCGGCGTCACGGTGACCGTCCTATGCCCCACCTTCGTCAAAACAAATATCGTCGACAATCCACGCATCGAGGAATCGGCGGCCACGCTAGCCGCCAACTTGATGAAGTGGACCGGCGTATCACCAGAGTCGGTAGCACGAACCACCCTGGATGCGCACGACCGCGGCCAGCTATACGTCCTGCCGCAACTCGACGCCAAAATCCTCTGGCAGCTCAAGAGAACCATGCCGGGTACCTTCACCCACGCGATGGGACTCATCCAGCGAATAACGCGTTGACACAACCTAGGAGGAGACATGGCTTTCGAATACGGCGATATGCTGCAGACGATTAAAGACCGCCAGTGGGCGCTGGCCGACATCGACTGGGACGCACCGGGTGCCGAGTTGATCACCGACGAACAGCGCCCCAGCCTGAAACAGTTCATGTCAGACGTGGTATGGATCGAGCATGTCGGTGCCCGCGCTTTCGCGGCCATGGCCCCCAAGGCGCCGTTCGACGCGTTGGGTGAGATTTACAGGTATTTCCACGCCGAAGAGCAGCGGCACGCCAACGTGGAGCTCGCTCTCATGCATCGCTGGGGGATGCTCGAGGAGGGCGAGACTCCGGTGCCGAACAAGAACATCCGGCTGGTCATCGAATGGCTGGACCGATACGCCGAAGCACTTCCGTTGACGGTGATCGGTGCTGCCATACCGGCTTTAGAAACCGCTCTGGACGGAGCACTGTTGAAGTTTTTGGTGGACGAGGTGTCAGATCCCGTGTGCGGCGAAGTTTTCGCCAAGGTCAACAGCGACGAGTCTCGCCACCTGGCGGTGGGTTTTCAGGTGCTCAACGACCTGGGCGCCAGCCCAATGAGGATCCATGCGATTCAGACGGTGGGAGCTCTTATCGACCCGAGGGTACTTACCGGTGCGTTGCTTTACATCCCGCTGCTGACCCGGATGCTGATAAACCTGAACGCCTGGGGCCTGTCCGAGGAAAGGCTGTACAACGCAGTCACCCGCTACTCGAACGTCGGCGATCGCAGCGAGCACACCCGCCGTGTTCCCCCCTATCACATCCTCAAGGCCCATATGTCTGCCACGATCAAGCACTCCCAACCGCTGCACTTCATCTCGCAGCGCCTCGGTAGGGTGATCGACCACTTCCCCACGCAAGTGCTCGGCAAGACGCCGTCATGGACTGATGAGCTGACCTATGAACCGGTGGCCAGATGAGCGACACGACCAGTGTTCTGATCATCGGAGCCGGCTTTGCCGGACTTGGCACGGCGATCCAACTACTCAAGCGGGGTATCGACGATTTCGTCATCCTGGAGCGCGCGGGCGAGGTCGGAGGAACCTGGCGTGACAATAGCTATCCCGGTGCCGCCTGCGACATTCCGTCATTGTTGTATTCGTACTCCTTCGAACCAAATCCGGACTGGTCGCGTGCGTACTCGGGAAGCAGCGAGATACTCGCCTACATCAAGGCCATGGTCGACAAGCACGCGCTGGCGCGCTTCATCTGTTTCCACGTCAACGTGACCGGCCTGGCGTTCGACGAAGACAGCGGCACGTGGACCGTCGAAACGGATGGCGGGTCAAGCTACCGGTCGCGCACGGTGGTGATGGCAAGCGGCCCACTGGCCAATGCAAATTTTCCTGACATTCGCGGACTGCACAGCTACGCAGGCCACAAAATCCACAGCGCGCGCTGGGATCACGACTATGACATGAGCGACAAACGTGTTGCGGTAATCGGTACCGGGGCGAGCGCGGTGCAGATTGTTCCGGAATTGGTGAAGACGGCGCGATCAGTCAAAGTGTTTCAACGGACGCCCGGTTGGGTGCTTCCCCGGCCTGATTTTCCGCACCCCAGTGTTGCCAAGGCCGCGTTTGGTCGGCTACCGATTCTGCAGAGCGCCGCTCGCCAGGCATGGTTTTGGGCGCACGAAGTCATGGCCGTCGGCATGGTGTGGAACACCCCGGCCACTACCGCCATCGCCTGGGCGGCCAAGGCGAACCTTCGTCGCCAGGTGAAAGATTCGTGGATGCGGCGACAACTGACGCCCGACTTCCGGCCCGGCTGCAAGCGCATGCTGATGACCAGCGACTACTATCCGGCTCTCCGACAGAACAATTGCAAACTCATCACCTGGCCGATCGCGACCATCTCGCCCATCGGCATTCGCACCGCGGACGGCATCGAACACGAGGTGGATTGCATCGTATTCGCGACCGGCTTCGATGTGTGCAAGGCCGGCACACCGTTTCCCATCACCGGCGTGGACGGTCGAAAGCTTGCGGAGGAATGGTCTAACGGCGCCTACGCCTACAAGAGCGTCAGCGTCTCAGGCTATCCCAACCTCTTTTTCACCTTCGGGCCGAATTCCGGGCCAGGACACAACTCGGCCTTGGTCTACCTGGAAGCGGAGATCCGCTACATCGTCGACGCCATCGGCATAATCATCGAAGGCGGTATTCAGACCTTCGACGTCAAAGAGGACCGGCAGAACAGCTATCACGCCCAACTCCAGCGTCGGCTTGCCGGCACGACGTGGAACTCCGGATGCAAGAGCTGGTACCTCACCGAAGACGGCTATAACGGGACCATGTATCCCGGCTTCACCACCCAATTCGCCCGACAACTAGCGAGGGTCGAGCTCGACGATTACTCGATGAGTTCACAGCCCCCTCCCCGCAAGAAGCCCAGGCGGGCGCGGCCCGAGTTGGCCGCGGAGAGTTCGCACGGCGCAAGCAAAGGAGGACGGCAGCGCAACGACGATCGCGTGTCCGTCGACAAGCGCGAAGGTGTTCGTTTCTCGGCGCAAACCGCTTCACCCGAGGCAGCATCACCGCGGATGGTGGATCGTGCTTGAGCCGCGACTGGCTCCGGCTAGGCAGTCGGCGACAGGTGCCTGGCATCAGCCCCCAGATAAGCCAGAAGGACGGTATGGACCACAGCGATAAGCACCGCTTCGAAATCATCGTGATCGGTGCAGGATTCTCCGGGATCGGAATGGGGATAAAACTCCTGAAAGCCGGCTTTTCGGACTTTCTTATTGTCGATGAGGCAGACGACGTAGGCGGAACGTGGCATTGGAACACCTATCCGGGCATCGCCGTCGACATTCCGTCGTACAGCTACCAATTCTCCTTCGAAAAACGGTCGTCATGGTCGCGGACGTATGCGCACGGCAACGAGTTGAAGGACTACGCAAGACACTGCGCGCACAAGTACGGTCTTAGCCCACGAATCCGCTTCGCCGTCAAGGTGACTGAAGCTTGGTTCGATGAGGACGCGACCCTGTGGCGCTTGCACACGGCCGCAGGACAGGACCTATCCGCGCGCTTCGTGATCAACGCCTCGGGCGTCCTGACACGCCCCAAGCGGCCGGATATCTCCGGTGTCGATGATTTCGGCGGGATCACCATGCATACATCCCGCTGGGACCACAACGAAGACATCGCCGGCAAGAGGGTGGCTGTCATCGGAACGGGCGCGTCGGCAGTGCAGTTGATCCCGGCAATCGCGAAAGACGTCAAGGCGCTGACCGTGTTCCAGCGCACACCGATCTGGTGCCTGCCGAAACTGGACTTCCCGGTGCCGCGGCTGGCAAGAGGGTTCCTCAAATACGCTCCCGGCGGACAACTCGCGGCGCGCGCAGCGAGTCAAACCTTCGTCGAAGTCACGTTCCCTGTCGCCGCTCACTTCCACACCGCCATTCCCTTGGCGTCACTCATCGAGCGTGCCGCGTTGCGGTACATGCGCAGCCAGGTGACCGACCCCGCCGTCCGTCAAAAACTGACCCCCCGTTACGCGCTCGGGTGTAAGCGCCCAAGCTTTCACAACGAGTACCTGGCCACATTCAACCGAGACAACGTCCACCTCGAGACCAGTCCGATAAGCCACTTCGATGCCGCCGCCGTCCACACCGTCGACGGCCGATCGCACGAGATCGACGTCCTCATCCTCGCCACAGGCTTCAAAGTGATGGAACCGGAGAACATGCCGACCTATTCGCTCAGGGGGATCGGTGGACTCGATCAAGCCAAGTGGTGGGACGAGAATCGGCTCCAAGCGTACGAAGGCGTCAGCGTGCCCGGATTCCCCAACCACTTCTCCATCTTCGGACCCTATGGATACAACGGTTCCTCGTACTTCACGCTCATTGAAGCCCAGACCAGGCACATCGTGCGATGCCTTCACCATGCGCGGTCCCGGCACGCCAACTACGTCGAAATAACCCGGCAAGCCAACGACCGCTTCTTCGCCGAAATGCTCAAACGCCGCCACCGCCAAGTCTTTTGGCAACCCAGCTGCGCAACCGCCAATAGTTACTACTTCGACAAACACGGCGACGTACCGCTACGCCCGACGACCACCCTCGAATCTTTCTGGCGTAGTCGCACCTTCGACCTTGGTGACTATTCGTTCGAGCGGCGCACCACTGAAAAGGTACTTAGCTCATCGTGACAACCCTTTACTCGGAACAGCATCCGAGCACGGCAAGTTATCTCATCGCGACGTCGGCCCGCGGGATCCTGCGCCCACTGACGCAAGCACTACCGTCTAACCAGTACGGGCTCGCGGTAATGGACCGGGTGCTTCGGGCGGCGCTCATTGCGTCCCGCCCGCGGCGCGGATTGCGAGTTGAACAGGTCGACACCGTCTTTGCTGGCGATCGGGTGAGAGGCGACTGGATCGTTGCCCCGGACGTCGACCCGGACGGGCCGCCGATTCTCTATATCCACGGCGGCGCCTTTTCCATGTGCTCCCCGCAGACCCATCGTGGTCTGCTAGGCGAACTGTCTGCCGCGTCGCTCAGGCCGGTGTTCGCCGTCCGCTACCGCCTGGCTCCGCGATACCCGTATCCCGCGGCCGCCGACGACGCACTGAGGGCCTACCGGTGGTTGACCGGCTCTGAAGAATCGGCGTCAAACCGCACGGTGGCGATCGCGGGAGATTCGGCGGGCGGCCAACTCGCCGTCGCGACCTCGTTGGGCGCGCTCGCACATCGCTCCCCGCCGCCCGATGGCATGTTACTCATGTCCCCCGTCGTCGATCTGACGTGCCAGCTGGCGATGGCACGTGAAACTCGCCGCCGCGATCCTTTCGCATCGGCCCGGTCCGCAACGCGTGCGCTCAGCCTCTATGTAGGCGATGCCCACCCGACCGACCCCCGCGTCAATGTCCTCGCCGCAGATCTCACCGGCTTGCCGCCGACATTGATCCAGGTCGGTGGAAGGGAGATGCTGCTCGACGACTCCCGTCAACTCGCCGAGCGCATGCGCGCCGCAGGAGCATCCGTGCGGCTTCAGGTGTTTCGCGGCCAGATTCACGTGTTCCAAGCCCTGTTTCGACTCTTGCCCGAGGCGCGTCACGCTTTGCACCTCAGCGGAGCGTTTCTCACAGACAGGGCCGAAGACACGTTTCCTTGACGCACGGGCCGAACGCAGGCAGGCGGCTAGCGCGCAGCAACCGCTTTTGTCACGCCCCACCGCGAAGGACCCGTTTGACAAACAGGGCAATTATGTATAACTATTAACATTGGTGGCCCAACTGTAAACAGCTGGTCGATCCTCCATCCCACGACGACCACAGGCCGGGGAGCGACAATGGTTAACCCGCTACACGCACCCGTCGATAAAGCCCGGGAACGGTTATCTTCGGTCATCTTGATTCCCGCGCCGCAACGGGTGGACGACGGACTTCGCCGGTGGAGTCGGCGGTGGCCAGTGCGTGAACTAGCCGCGCCCCCGGCCGGAAGCGGACTGCGACCGGTTCTCGGTGATGCCGGGCTCCCCTTGGTCGGGCACACCCTCGACTACATCCGGTTTGGGTCCGACCTGGGCAGAGAGCGCTACGAACGGTTCGGATCTGTCTCGTGGATGGGAGCGTTCGGCACCAAAATGGCGGTCATCGCGGGCCCCCAAGCTACCCAGGAGGCGCTCACCACCAACGCAAAGGCGTTCTCGCAAGACGGCTGGGCCTTTCTCATCGACGCGTTCTTCCACCGCGGATTGATGCTGATGAGCTTTGACGAACACCTCATGCACCGGCGCATCATGCAGGAGGCCTTCACGCGGCCGCGACTGGCCGGCTACGTCACCCAAGTGACCCCTTGCGTCCGCGCAACCCTGCCCACGTGGCCGACCGGCCCGTCCGTCCGCATGTACCCGCTGTTGAAAAACCTGACCCTCGACATCGCCACCGATGTGTTCATGGGTGGCCGAGGCAAAGACAGCAGCGACGCCATTAACCAGGCGTTCGTCGCTACGGTACGCGCGGCCAGCTCACTCGTCCGCGCGCCGCTTCCCGGCACCCGCTATCGCGCCGGGATCCGCGGCCGACGGGTGCTCGAGGAATACTTCGCCCGGCACTTGCCGGCCGCCCGGGCCGGCAACAGCAATGACCTGTTCGCCGCGCTGTGCCATGCCAGCACCGAAGACGGACAACGTTTCAGTGACTCCGATGTCATCAACCACATGATTTTTCTGATGATGGCCGCTCACGACACATCGACCATCACCACCACCGCGGTAACTTATTACCTGGCAAAGCATCCAGAATGGCAAGATCGGGTTCGCGCCGAAAGCGATGCTCTCGGCGACCGATCACCCGAGATCGACGATTTGGAAGCGCTCAGGTCGCTCGATCTGGTGATCAAGGAATCCATGAGACTCGTGGCGCCGGTCCCGCTAGTCATGCGCAAAACAGTGCAAGACACCGCAATAGACGGCCACTACATTCCCCGCGACACGCTTGTGGCGATCACCCCCGCCGTCAACCATTTCGTCCGCGAAGTCTGGCACGATCCGGATCGCTTCGACCCCTTACGTTTCGACGACCCGCGCCGCGAGGACCAAGCTCACCGCTTCGCGTGGCTGCCCTTCGGCGGTGGCGCGCACAAATGCATCGGCATGCACTTCGGCACCCTCGAGGTCAAAGCGATCCTGCACCAGATGCTGCGCACGTTCACCTTCGGCCTCGACACCGACTACCGCATCCGCTGGGACAACACATCGCTGCCGATCCCGGTCGACGGGTTACCGATCACGCTGCGCCGCCGATGAAGACAGAATTTGCGCGGTTCCTCGCAGCCACCGAATTCCTCGACTGGAAACACGATGCCGTGCAGCAGTTCACCGAATCGGCGACACGCAACGCCACCGATTCCGTCGATAAGGCGTGCCGCATCTTCACCGCTGTCCGTGATTCGATCTGGTACGACCCGTATTCCGTCTCCGACGACCCGCGCCAGTACCGAGCCAGCGCGGTCGCCGTCGCCGAGCGCGCCTACTGTGTCCCCAAGGCGGTGCTCTTGACGGCTGCATGTCGCGCCGCGGGGATTCCGGCGCGGTTGGGTTTCGCCGACGTCCGCAACCATCTACAGACCGCGAGTCTCCGTGAACGGATGGGTGGTTCGGACGTTTTCGTCTACCACGGCTACAGTCAAATACTGCTGAATGGTCGGTGGGTCAAGGCCACACCGGCATTCAACCGCGAGTTATGCGCGCGCTTCCGCGTCGCTCCCATCGAATTCGACGGTCAGCGAGACGCCATGTTGCACGCCTACACAGGCGATAGTTCTCAACACCTGGAATACCTCCATGACCGTGGTGTTTTCGACGACCTTCCCCTCACGGAAATCATCGACGCGCTGCGCGACAATTACGGCGAACTCATCTACGAACCTCCTCCAGTGCCGGACTCATTCACCAACTAGCAGTTTGAAGGATTGTGCCTGTGCAAAGCACCATGCAGGATATCCCCTTGACCGTAGCCTCGATCGTCAGGCACGCGACATCCATCCACGCTGACAGCCAAGTCGTCACGCCGACCGGATCGGGCTACCGCACAACGACCTACGGTGCGCTCAAGCGACGAATCAGCCAGTTGGCCAACGCACTACGGAGTCTGGGCATAACTGACGATCAGCGCGTGGCCACCTTCCAATGGAGCAATCAGGAACACCTGGAAGCCTACTGTGCGGTGCCGTCGATGGGCGCGGTGCTTCACACCCTCAACCTTCGACTCACCGCAGAACAACTTGGCTACATTTCAGATCACGCCGACGACAAGGTCATCATCGCGGACGTCTCTGTGGCACCGCTTCTAGCGAAGGCACTGCCGACGATGTCGTCGGTGCACACCGTGATCGCAGCGGGCGACGGCGACCTGGAGCCGCTGCTGGCCAGCGGTAAAAACGTGCTGCGCTACGAGGACCTGCTTGCTGATCAAGACGGCGAATTCGACTGGCCAGAGCTCGATGAGAGGTCGGCCGCGGCGATGTGCTACACCAGCGGCACTACCGGAAACCCGAAAGGTGTTGTCTACAGTCATCGTTCCACCTATTTGCACTCGCTGACTGGCTGCACACCCAACGTGCTGTCCATCGGTGAAGAAGACCGCGTCTTGGCGATCGTCCCGATGTTTCACGCGAACGCATGGGGGCTGATCTATTCCGCGCTGATGTGTGGAGCCGACCTCGTGCTGCCCGACCGATACCTGCAGGCGGCACCGTTGGTTGCCATCATCGAGGACACGCAGCCGACCGTGGCCGGTGCGGTACCGACGATCTGGAATGACGTGCAGCATTTCCTGGAATCCGAACCGGAGCACGATATTTCGTCGCTACGCCTGGTCGCCTGCGGCGGGTCGGCCGTTCCAAGGTCACTGATGGAGCACTTCGAGAGTGAATTCGGTGTCCCGATCCTGCAGGCCTGGGGGATGACCGAAACCTCGCCGCTGGCAACCGTGGCGCGCGCGCCGAAGGGGACCAACGGCGAGCGCCAATGGGAGCTACGCGCTTGTCAGGGTCGTCCCGTCTGCGGTGTCGAGATTAGGCTGCGTGGCGACGATGGCCGTACCCTGCCCTGGGACGGACGGTCTATCGGCGAGATCCAGGCCCGCGGACCGTGGGTCACCGGCTCGTACTTCGGCGACAACGACTCCGACAAGCTCGACGAAGGATGGCTGCGCACCGGCGACGTGGGTCGCATCGATCAACACGGCTACCTTACGCTTACCGACCGGGTAAAAGACGTCATTAAGTCAGGTGGCGAATGGATTTCCTCGGTCGACTTGGAGAATGCGCTCGTTGCCCATCCAGCCGTGCATGAGGCGGTGGTGATCGGCGTGCCCGACGAGAAGTGGCAGGAAAGACCCTTGGCGTTGATCGTCACGAAGACCGAAACCAGCTTGGATATCAACGAATTGCGGGTCTTCCTGGACGGCGCGGTCGCCAAGTGGTGGATCCCGGAGCGCTGGGCGTTCATTGCTGAGGTTCCCCGAACCAGTGTGGGCAAATACGACAAAAAATTGCTGAGAGCACGCCACGGCGCCGGCGAATACCAGGTCGTGTACTGCGGCTAACCCGAAAAGCCGCCAACGTCGTCAGCAGCACCTAACCGAAAGGACACCATGACAGTCGCCTCACCTTGGCTCAGCCCGGAATTGGAAGCGCTTCGTGATCTCGCCGCAAAGTTCGTTGCCACTGAGATTGCACCCCACTCAGAGCGCTTCGCCGAGCAACACCATGTCGACCGGGCGGTGTGGGAACGAGCAGGCGAGCTGGGCCTGCTGTGCATGTCGATGCCGGTCGAATACGGCGGCGGCGGCGGGACGTTCGCGCACGAAGCAGTTCTGCTCGAAGAGCAAGCTCGAATCGGGGACAGTTCGTGGGGCGCCGGCCTGCACAGCGGCATCGTCGCACACTACATCCTGCACTACGCACGGGAAGACCTGAAAAGGCAGTGGTTGCCCAAGATGGCGTCGGGCGAATTGATCGGTGCCATTGCGATGACGGAGGCTGGAACCGGATCTGACCTTCAAAGCGTGAAGACGCGCGCCGTCCTCGATGGGGACGAGTACGTCATCACCGGCTCGAAGACGTTCATCACCAATGGTCAGCAAGCCGATCTCGTCGTCGTCGTGGCCAAGACCGACCATACCCAAGGCGCCAGCGGTATCTCGCTGATCGTCGTGGAAGCCGATCGCCCCGGGTTCCGGAGAGGACGAGTCCTCAGCAAAATAGGTCAGCGCGGTCAGGACACATCTGAATTGTTTTTCGACGGCGTGCGCGTCCCCAAGACGCATCTGCTAGGCGACACCGAGGGGCAAGGCTTCTTTCAGCTGATGACGCAACTGCCGCAGGAGCGACTTATCGTCGCGGTCGGAGCGGTTGCCGCCATGGAATTGGCCTTGCACCAGACGATCGAATACACGCGCCAACGAGAAGCATTCGGGCGAACGATCTTCGGGTTCCAAAATACCAAGTTCACCCTCGCTGAAGCCGCCACCGAAACAAGGATTGCGCGAGTGTTCCTCGACCACTGCATCTGTCTGCATCTCGACGGTAAGCTCGACGTGCAAACTGTCGCGATGGCCAAATGGTGGACGACGGAACGGGCGATGAAAGTCCTCGACGACTGCCTGCAGCTGCACGGCGGGTACGGATACATGACGGAGTATCCGATTTCGCGTCTCTGGGTTGATCAGCGAGTACAGAAAATCTACGCGGGGTCTAACGAAATAATGAAAGAGATTATTTCGAGGTCGCTTTGACAAGATAGCGACGACCGAACGCCCGGTGTATCAACGCAGATGAGGATCTGCTATTCGAGACAGGCAAGCTCCACTGCAGACAAAAGCCATCCCGGTGCCGTATCGGCGGACACGGCGGATCCGTCAAGCTCCCGCGGTTCCCCCTGGCCTCAGGGCTTATTCGCGGACGAGGAGTGTCCGGCTGCAGCTGTCCTCTCGCCACGATTCGTTCTCACGACGTGAATCCCGGAATCCGGCAACGCCGTCAGCCCACGTTGCCGACCTCGGCGATCTTGATTCCAGTAAGGAAACTTCTCACATGCTGCGTCGGGGGCGTGATGCATCACGTCAAGTTGCCCGCGAAACCTGATCCATGCATCACGTAAGGAATGCCCGCGAAAACGAGGTCAACTGGCGGTCTTGTTCTGGATGCGGATGCCGGATCTGACCTCGGGTAGGGCGGTGGGGATGGCGGCGAGGTAGAGGTGTTCGGTCTTGTTCTTGGCGAGTCTGAGCAGGGCGGCTTGTAGATCGGCGATCTGGCGTGCGATCGCGGCGGGGTTCAGGGTGTCGCGGTAGGCAAGCAGCTCCGATTCTTGGGCTGGCGAGAGGACCCCGGCTGCCAGCAGCCGGTCCAGTGGGGTCATGGGCTCGTCGTAGAGGCGGCGGCGCTGGCCGTCGCGGCCAGCGCCGTAGCCGATGGGTTTGATGGCTCTTCGTAATTCAGAGTGCATTGACAAGTTGGTGGAGTGCTCCGCTGTGTAGTAGTGAGCGCCAACGGTAGTGGGTGAGGTTGCGGAATCCGAGGGCGTTGCGGCGCAATGCTTCCAGGCGGCCGTTGATGGCCTCGGTGGGTCCGTTGGAGACGTGGTGGTCGAAGAAGGCCAGGATGTCGGCGCGGCGGCGCGATAGCGTGCGGCCGAGTTGGGCGATCTCCTCCAATCCGGCGGGTACGCCGCGCCGACTTCCAGGCGGCCGTTGATGGCCTCGGTGGGTCCGTTGGAGACGTGGTGGTCGAAGAAGGCCAGGATGTCGGCGCGGCGGCGCGATAGCGTGCGGCCGAGTTGGGCGATCTCCTCCAATCCGGCGGGTACGCCGCGCCGTATCGACTCGATCAGCCTGGTCATTGCCTTCTTGCCGTGACGTCGGTTCGGGTCGGCGTAGGCGGCGATGATCTTCTGATAGATCAGCCAGGCGACCTTGACGGCGAGATGGTCGTCGCCGTCGAGCACCTCGGTCAGCCGGGTGTATTGGCGTGGGGAGAGCAGCTGCAGGCGGGTTCGGGCGATGCGCCGGATCCCATAGAGCGGGTCACCGGTGTGTCCGCGCCGACCCAGGGTCTGCTGCTGGATGCGTTGGCGGATCAGGTCGAGCTTGGTCCCGGCCAAAGCCACAACGTGGAAGGGGTCCATCACGGTGACCGCGTCCGGGATGACCTCGGTGGCGGCGGTCTTGTAGCCGGCGAACCCGTCCATCGCAATGACCTCCACGGCCCGGGCAAAGTCGGTGGGTTGGGCGGCCAACCACGTGGCCAGTGCGGTCGCTGAGCGTCCTTCGACCAGGTCGAGCAGGCGTGCCGGGCCGGTCTGGTCGTGGGTAGGCGTGAGGTCGATGATCAGCGTGACGAACCCCTCTGTGCCGCGACGCCGAGGCGCCCAGCGATGCTCATCGACACCGATCACCGTCACCCCGGCCAGCCGATCCGGCCCGGTTGTGGCGATCAGGCCGGCGGTCGCACGCATCGCGATGGAGCTGACAGTATGCCAGGACACCCCGAGTTCGGCGGCGATCGCCGAAATGGTGGTGCGGTCGATCATCAACCGCCGCAATACATACCGGGCACAGCGCCGCGTCGTCGATGAGCGCGGGGCCGCCAACTTGCCCAGATCCTGGTTGAACACTGCCCGCCCACACGCTGGCGTTGTGCAGCGGTAGCGAGGTAGGGCACCCTGCAGCACCAGCGGGTAGCCGGCCACCGGCAGATCCGTCAACGGCCGAGTCACAGTGTCGCGGTAGCGGCCCTCCCGGCCGCAGTCCGGACACCTGGCGTCACAGGCCACCGGCCTGCAGTCGTCGTCGTCTCGTCGACCGCGGCGTCGGTGATCGTCACCCCCAACTCGATGGTGCGCATGATCGTGTCGGCAACAACAGACGGCGGGCAGGCAGTAGCCTCAGGCAAGGGTCACCTCGGTGGTGTTGGTGAAGCGGCGTGTAGGAACCTGAATCGTCACCCACCGAGGCCCCACCTCAGCTCAACGACACGAACCCCCACCGCGGATATCCGCCAACCACTGCTGCACGCTCATTTCCGCAGAGCCGGTTTGATGGTGGGCGTCAGGTAGTTGAGCCGGTCGTTGACCAGCCTCCAGAGCCGGTTGAGCACCGCACGTTCCTCGTCGGTGTCATAGCGGTAGTAGAACCCATACTTGCGGACGAGGTGGTTGTTCTTGGACTCGATTGTGGCCTGATCGTTCTTCTTGTACGGCCGCGACCTGGTGAAGAAGATCTCCATCTGCGCAGCCCACTTGATGACGGCCTTGTTGAGGAATTCGGTTCCGTTGTCGAAGTCCAAACCGGTTACCTCGTAAGGTATTTCATGGACACCGGCTTTGAGGGCGCCGAGGATGTGAGTGTGGGCGTTGTTGCGTTCGGTGCGGGTGAAGACCCAACCGATATGCATATCGGTGAGGTTGACGGTCCGGGCGAACTCGCCTTTGAGGGTTGGACCGCAGTGCGCGACGGTGTCGCCTTCGAAGAACCCCGGAGATCCCTCGACCTCGTCGGTTGCCTTGCGGATCTTGATCGAAGACCGCAGCAACGGGGAGGCCTTGGTGGTCGATTTCCCCTTGATCTGGTCGCGCGCCTTGACCGCACGCAGGTAGCGGTCGATCGTCGCGCTGCTCATCGCCAACAGCTCGGCACGCACCTGCGGGCTGTAGCGGTCCACACCTGCGCGTCCGGCCGGGTTTCCAGCAGGCGAGGTACGACGCGGCGACCAATAAACCCGGTACCGCCGGTAACGACATAGCGCATGCAAGCCATCGTGGCGGGTCACACCGCGCACGTCAACCATGCTGTCCAGGCATCAGCCGGCGAAGTTGCGGATGCCGTCCCAGTCCACCAGCGTCCAGCCGGTCATCGGGTTTCCGGTGATCACCACGCGGCCGACGTTGGGCAGCGGATGACTGGTCGCCAGGCTGTCCTTGGCGTTCTTCGTGTTCATCAGCGTCCAGTACTCGATGGCGTACAGATGCGAGAACACCACCGGTTGGTTGTGGCCGCTGTTGTAGATCTTCTGCACGGCCGCGGTGAACCAGTCGTTGAACTCCTTGCCGGTGATCGACCCGGGGATGCGGTCTCCGACGTCGCCGTTGAGCCAGTCCGCCGGTACGTCGAGGGGGCCATCGAGACGGGCTTGCCCTCGTACCAGCCGGCGTTGATCTCTTGGATGCCTTGCAGCACCTCGACTTGCTTGCCGAGTTCGGCGGCCAACGGCGCGGCGGTCTGTTGCGTTCGCACCATGGTGGAGGCGTAGACGGCGTCGTACTTGTTGTGGGCGAGTTGGTGCGCGACCTGTTCGGCCTGCCCCTTGCCCTCCGGGGTCAGGCCCGGGCCCGGCACGTCGGTGTCGATGACGCCGCTGGCGTTGGTCTCGGACTCCGCGTGCCGGACGAACGTCACGGTGATGCTGTGGGCCTGCGGTGACCCGCCGCAGGCGCCGACGATTACCGTTGCGGCCAGCACGGCTACCGCTTTTGAGGCCTTCCTGATCAAGCTGGGATTGCGCATGGCGATAGCCTGCCCCGCCGACGGTGCCGGTGGGAAGGGTTTGCGATGGTTGGGTGGCAGAAAAGCTTGAAGGGAGACTCGTATGGCGATTGACCCGAGTGCCGTCGGTGCGACGACGGAGCCGATGCTGTTCGAATGGACGGACCGGGAGACGCTGCTCTACGCGCTCGGTGTCGGCGCCGGAACTGACGACCTATCGTTCACCACCGAAAACAGCCACGACATCACCCAGCAGGTGCTGCCCACCTATGCGGTGATCTGCTGCCCGGCGTTCGGTGCGGCGGGCAAGATCGGAAAGTTCAACTGGGCCATGCTTTTACACGGGTCGCAGGGCATCCGGCTGCACGCACCGCTGCCGCCGGCGGGCAAGCTGTCCGTGGTCTCCGAGGTCGCGGACATCCAGGACAAGGGCGAGGGCAAGAACGCGATCATCGTGCTGCGCGGCCGCGGCACCGACCCCGACTCGGGGGAGCTGATCGCCGAGACACTCACCACGTTGGTCATCCGGGGCGAGGGCGGGTTCGGGGGAGTGCCGGGTCAGCGGCCGATCGCGCCGGAGTTTCCCGACCGCGAGCCCGATGCCCGGATCGCGCTGCCCACCCGTGCGGACCAGGCGCTGATCTATCGGCTCTCCGGTGACCGCAACCCGCTGCACAGCGACCCGTGGTTCGCCAGGGACATGGCCGGTTTCCCGAAGCCGATCCTGCACGGGCTGTGCACCTACGGGGTGTCGGGCCGCGCGCTGGTCGCCGAGCTGGGCAAGGGCGTGGCCGCCAACGTCACGTCGATAGCGGCGCGATTCACCTCGCCGGTGTTTCCAGGGGAGACGCTGACCACGCTGATCTGGCGGACGGAACCGGGCAAGGCGGTGTTTCGGACGGAGGCTTGTGGCGCCGAAAGCGCGAACGCGCGGATCGTGTTGGACGACGGCGCGGTGGAGTACGCGGAGGCCTAGCCGATGGCTTAGAACCCGGTACGTCGCCCCGGCGCGCAGGCGTTCACTGGTGCGCCTGGCCTGCCGTCCAGCCATGACCTGTCCCGCATTCGGCGGGCTTCGGGGGGATCGCTCGGGCGCTAAGCTAAACAGCTATGTGCTACAGTTAGCACATGTCTACGGTGGGCGTTCGTGAGCTGCGGCAGCGGGCCAGCGAACTCCTCCGTCGGGTCGAGGCCGGCGAGACGATCGAGATCACCGACCGTGGTCGGCCTATCGCCCTTCTCTCGCCGATGCCGGAGGGCGGTCCGTACCAGCAGATGCTGGCAAGCGGCGGGATCGAACGTGCGACGCTTGACTTTGATGACCTTCCCGAGCCGGTCCGACTCAAAACGGGTATCGAGCTGCCGTCCGTGACGCTTGCGCGCCTGCGTGAGCACGAGCGTTGATGGCGGCCATCTACCTGGACTCGTCCGCAATCGTCAAGCTTGCAGTTCGTGAGCCAGAGTCGGATGCGCTGCGTCGCTACCTTCGCACCCGGCTGCCGCGGGTGTCGAGTGCCCTTGCGCGGACGGAGGTCATGCGGGCTCTGCTCCACAAGGGTGAATCAGCCCGAAGAGCCGGACGCCGGGCGCTCGCGAGCCTAGACCTACTACGCATCGACAACCGATTGCTCGATCTTGCTGGTGGGCTGCTGCCAATCGAGCTACGCACCCTCGATGCAATTCACCTGGCGACTGCCCAGCGGCTCGGCATGGATCTTGGCCGGTTGTGCACTTACGACGACCGCATGCGCGACGCCGCCGAGGCGCTCGGCATGGCAGTGATTGCCCCGTCTTGATCGGCTACCTAGGGTGGCGCGTGAGGCGGCCAACGCTTCATGTCCCGGCATGTCGCGCCAACCTCGTGCCACCGCCGAATGGGGACACCGTCGTGCTGGATCACTCGAATGTTGGCACCCTGAGCGCCGTTAGAACCGTTGCCGTCGCTAATTTACGCGGGCGTCACTTAACCGCTGTGCCAACCTTTCGGTGAACTCGGCGGCGCGCGCGGGACTGTCCAACGCAAACAGCGCGGCGGTGGCGCGGTCGCCGTCTTCGCTGTGTCGCACCAGGATCGGGATACCATCATCGCGGACCGCGTCGAACGCGTCCTCGTCGGTGATGTCGTCGCCGAGATAGATGGGCACCAGCGGACGCGCGTCGGCCTCGCGCAGGTGATCGATCACCCAGCGAAGCGTCTTTCCCTTGTCCCAGTCCATGTCCGGACGCAGCTCGATGACTTCGCGACCCGTCGTCACCCGAAGTCCGTCCCGCCGGCCCGCCGCGCGCACCGCCGCGGCAACCTCGCCCACGCGGTCCCGCGCGGCGTTGCGGTAGTGGACCGCAACGCCAAATCGCTTGTGCTCCATCATAACTCCGGGGATCGAGTCGAGCCGGTCGCGCAGCTCGGCGGCGGCCTGTTCGAGCACCGGTGTGGCCGCCGCCGCGGCGTCGTTCTGGTGGTGTGTGCCGTCGGGTGCGGTCAGCTCGAAACCGTGGCTGCCGGCATACCAGATCCCGGGCACACCGAGGCGCTGTGACACGTCGGCGAGGTCGCGGCCGGACAGAACCGCGACCGGGCATTGCGCGGCCAGCTTCCGCAGCGCCTCGACCGCGGCGGCGACGGGCCGGGCCGCGGCGGGATCGTCGACGATGTCCGACAGCGTGCCGTCGAAGTCGAAGAACATATGGCCGGCCTCCGGTCGGTGAGGGCACCGAGGGCCTGCACAGCATCGGGTAGCTGGGACATCCGGTGGTCCCCGGTGCGCACGGCGACCTCATCCAGATCGCCGACCACGGCGTCGGCGCCGACGCGCCGCAGGGCGTCACTTTGCCCTGTTCGGTCGAGGCCGATGACCAACGCGAATCCGCCGTCGCGCGCGGCCTGGACGCAAGCCGCGTTGTCGGTAAGGACGGCGCATCGCCCCGGGCGGACCGACAGCTTGTCTGCTGCCTCACTCAGGGTGTCGCGGACGTTACCGTTCGACGCGAAGACGCCGGTGTCGACGCCGGCTTCGCGCAATCGCCGGGTCAGCGCCTGGGTGCGGTCCAACGCGGTGTCGAACAGCACCGCGTCATGGCGGCGCGGGTCGATGGTGACCGGCATTGACCAACCTTCTCACGGTGTTCAACGCCGGTGAGAGCGGGTCAGTGACGTGCCGGCGTGGGTGCCGACGGTCGCGGCCGCTGCGCCTGGCCCGGAAACGCGCGCGCCGCGCGCGTGCGCCGGCGGTCCTTGCTGAACAGCAACACCGAATCCTGGCTGAGCGCCACCATCCGTGCCATGCCCAGCTCGATACCGGCTGCCAGCTGCTTGACGTCGGCCGTGGCGTCGTATTCGGCGGTGATGCCCGAATACCAATTCGTCGCCGTAGCTGAGCATCGCGACCCCGGTGCTCAGCTGCAAGGCGATCGGGGGGATCGGCAGCAGGCGCTCCATCGTCTGGCCCATCAGCCGCAGCTGATGGCGAGGCCCGGGCGCGTGGTTCGCCAGCGTTACGAGGCCGCGCTGCGGGAGCCTGGGTAACAGTTGTATGAGGTTGCCGCGCAGCATAGTTGGCAGACAATTGATCGCAGACTCCACGATACCGGGCGGAGATTTGTCGGCGTGCTGCGCTTTCCACCGGCTGTGCACGGTCCGCAATTGCTGGACCGGGTCGTCATGCTCGACGGGCAGGTATGGCAGTAGTGCCGAACGTACCGGCATCGGCACCAGGGTGCGCAGCGAGTCCGCCCGCGGTTCTTCGCCGCGGCGTAGCAGAACCCTTCGGAAGCCCTCGGTGATGGCCGCCAGCGCGACATCGTTGACGGTCACACCGAATTTGCGGCACACGCACTCGACGTCGGCAATCGGGACGCGCACCGTGCTGTAGCGCCGCAGGACCGGGTCGACCGAGGGCCGTGCCGTCGGCCAGATCGCCCCGACGAAGTTGCCGGCGAGTGCCCCAGCCCACTCCAGGGGCCAGCCGCGCTTCGAGGCCTGCGGCGGCGAATCATGTTTGTCGCCAACACCGTTCGCGAATGCATCGTGGTCGGCGTCGTCGCAAAGCCGGGTGAGCAGGTGGGCGGCTGAGTTCCCGTCGGCCAAGCCGTGGTGGATCTTCATCAAGATTGCCCACCGGCCGCCTTTCAGGCCCTCGATCACCCAGCACTCCCACGGCGGACGGTCCAGGTCGAGGGGACGCTCCAGGGCGTGGGCGATCGCGCCGGACAGCTGGGCGTCGTCGCCCGGGCGCGGAATCGCCACCCAGCGCACATGATGGGCCAGGTCGAATCCGGGACAGTCGATCCACTCGAAGCTCTGCGTCCGCAGCACCTGTGTGCAGCGCGGTATCGACTGAATCCGTTCCGCCAGCAGCTGTTTCAGCAGTGCGTAATCGGGGACGCCACCATCGACGATGGCGACCGCGCCGATCACCAGGCTGGCGTACTGATCGGGATCTTGAGCTCTCAGGTACGCCGTATCCAGTGTTATCGCTTGCGCCATGCGCAGTCCCCGCCCCTCGTTTCTCGCACTTGTACCAGTATTTGCGCGGGACCTCCGGGGCGGTAGGCCAGGAGCGTTAAGAATGTGTTTAGACCCGTTAAACAGCTCGCCTAAGTCGAACATACTTATTGCTTATCTGCTTAAGTGGACTCGTTTGCTTAAAAAAATTCGTCAAAAGTACTGCCGGGCAGTGGTTTAGCAGTTGCTCGCAGAGTTTGCTCTTGGCCTTCGGCGGCGCCGATGAGGTCGGCTAGTGGGTGGGGATCGGTGTTGACGCTTTGTTGCAGGAGTCGGTAGAAGAGCATTCCGCGGGCTTTTGACCTGCGGCGATTGAATCTGAAGGTGAACTCGTCGAGGTAGTACTGCAGGTGCTCGCGTTCCACGCGGGTGTAGCGGCCATGACAGGAGCGATCGTCGGCGCCCGCGACGGCGTTGAATCCATCCCTGCTCGCTGGCTCGAAGCACTCGAAGACGGCGACCGCGGACGCACCCACGTGAAGCAGCTCGCCGCGCTTCTGCTCAGGTAGCGCGCTCTGCGCCCTACCCCCCCGCTCACCTAGGTGCGTGGGTCGGTATCCACGAGTTGTTGGTGTGTCACGCTGATGGCGACGTGGATGGTCGGGAAAACTGTGTCCATGGATTTGATGACGGCCCAGGATCAGCTGTTTGAGACCGAGTCCGCGCGGCCTCGCTCGTCATCGTCACCGGGCGAGGTTTCGGTGGACAAGACGTTTCGGGCCTATGACCAGGATCAGTCGTTTTTGATGCCGCCGTCGTTGCGGGATTGGTTGCCTGACGATCATCTGGCGTTGTTTGTGTCCGAGTTGGTCGATGAGGTGCTTGATCTGGCAGTGTTTTTCGCCTCCTACAGCGAGGCCCGGGGCTTTCCGCCGTATCACCCGCGGCTGATGCTCAAGCTGCTGCTCTACGGGTACACCAGCGGGGTTCGTTCATCTCGCAAGATCGAAGCCCGTTGCCATGACGATGTGGCGTTTCGGTACCTGGCCGCCAACACCGCACCGGACTTTCGCTCCATCGCCCGCTTTCGGCGCCGTCACCTCGCCGCGCTGGAAGCCCTGTTCCTGCAGGCGCTGACCCTGTGCCAGCAGGCGGGCATGGTCACGATGGGCCGGGTGGCCCTCGATGGCACCAAGGTCAAGGCCAATGCCTCCCGTCACAAGGCGATGAGCTATGACCGGATGTGCGAGGCGGAGCCGGCCCTGCAAACCCAGGTCGAGCAGATCATGCGGGAGGCCGAACGCGTCGATATCGACGAGGACCAGGCCCACGGCCCGGACAATCGTGGCGGTGACCTGCAGGGCGAATTGGCCCGCCGTGAGAGCCGGCTGGCCAAGATCCGCAAGGCCAAGGCCGACCTGGAACAACACGCCAAAGACCAGGCCGCGGACAAGGCCCGGGCAAGGGCGCAAAACGCCGGCCATGATGACGACGCGGCCGCGCGGGCCGCCGAGCAGGCAGCACAGTGCGCGACCGTCAAGCCCAAGGCGCAGCGCAACTTCACCGACCCTGACGCCCAGATCATGAAGACCGCCGACGGCAGCTTCCACTACTGTTACAACGCGCAGGCCGTCGTCGATGAAGAACATCAGGTGATCGTTGCGACCGACTTCGCCGAATCCGGCGCCGACAACCCCGCATTCGGCGAGCTGCTCGCCCAGACCATCACCAACACCGCGACCACACCGCGTCAGACGCTCGCCGACGCCGGCTACTTCAGTGAGAACAACATCGACGCCGCCCACAAGGCGGGCACCGATCCGCTGATCGCGACCGGCCGGCTCGCCCACGGCGAGCAGGTTCCCGACGCGCCACGGGGACGGACACCGAAAAATGCGACACCAAAGGCGCGGATGGCCCGCAAACTTCGCACCAAGAAGGGCAAGGCCGCATATTCGCGGCGCAAGGTGATCGTCGAGCCGGTGTTCGGGCAGATGAAGACCACCCAGGGGGCGAGTCGACTCCTGCTCCGCGGCCACCATCACGCCCGCGCCGAATGGCGCCTGCTCGCCGCCTGCCACAACCTGCGAACCCTCCTACTACAACATTGCAGCGCAGGCTGCGGCCGGCTGAAAGGGTCGTGCGCAGCGAGTTACGGCCACCGATCCGCCATCCCGCGGAATGCGGCCCGCCCGATCACACCACCAGGCCAACAAAACGCCGCCCGATGCCCTCCGTCCAGGACAAATCCACCTGCCGACCCGACAAATCCGTTACCGACCCACGCACCTAGCCGGGGGCAGCAGGAATCAAGATCACTACAAGTCAAGTCCCCACGGAATCAGGGGAACCCCTTCACCCGAGCTGCACGGCGTATTGACGGCAGAGCACCTACGATTGGCCGCTGATCAGCCCGCACCCTACTTTCCCGTGCTGGTGACCGGTGCCGCCGCCTCGGCTCCACCGGCGGCAAGCTCACCCTGGTCCGCAGCACCCACTGTCTTTGACAGGCGAGCACCCAGCCGCTGAAATGCGTCCACCGAGAATGGCTGCATCATACGGCGGTTGACACCAGGGGCGATACGGAGCATGAAATAGCCCAGCCAGGCCTCGGTGCGCACCGGCACGACCGCCAAATCAAACCGTACCGCACGTACGACGGCACGAGCTACGAGGTCCGAGCTCATCGGCGAGACCCTAAACTTCTCGCTAAATTCCTGGAGCTTCTTCGTGAACTGCTTTCCTTGTTCGATCAGGTTCTGATCGACGCCGACTACGATCGCGCGATCAGCGATGTTGGTGTTGATCACACCCGGGCACACGGCGCTGACGCCGATGCCTCTCGGTCCGAGTTCGAGCCGCAAGCACTCGGTCAGCATCTTCACGCCCGCCTTGGACACCGAGTACGGCGCCATCACCGGCGTGGGTGTGAACGCCGCCGCTGACGCGATGTTGACGATGTGGCCACCGCCGCGCTCAACCATCTGGGCGCCGAACACACGACATCCGTGGACGACACCCATTAGGTTCACACCGAGTTGGCGGTCCCAATCCGAGGGACTCAGCTGCAAAAAGTGGCCGCCCACCAAGATACCTGCGTTGTTGACCAATACATCGGTGTAACCGTGATCGGCTAACACATCGCGACCGAACACCGCCCAGGCGTCGGGGTCGGTGACGTCCAACTGCGCCGCCGACGCGCCGAGGCCGTAACCGCGGATCATCGCGGTGGTCGCTTGTGCCGCATCCAGATCGATGTCGGAGACCACGACGTGGGCGCCGAGCTTAGCGAACCTGATCGCTGTCGCCCGGCCAATGCCGCTTCCAGCCCCGGTGACCACCACCAGGCGCGGTCGCAATCGGTTGAACTTCACAGGCTCTCCTTCGTCATGGCCGCGGCTGCGTCCAGAACCGCAACGCCCCTGCTGTATCGGTAGACATCAAGGTTGTAATAGCGGTTCTGCCAGTACATTTCGCCGTGCGTCGACGGCCGAAACGGTGAATCGCCCTGGTTATTAATGTAGTAGGTGTTCGAACCCGCACACGCCGGAGTGAACAGGAAGTTATTCTGTTGGCGCTTCAGGCATTTCCGAAAATACTCGTCGTGGGCTTCCTGACGAATCTCGCAGACCGTTGCACCGCGGCGCTTCGCTTCGGCTATGGCGCGGCTCAGGTGAGCCGATGTCGCTTCGATCATCCACAAGTACGAGCCGAGCACGAATCCGTAGGGCCCGGTGATTGAGAACATGTTCGGAAATCCGGGAACCGAAACACCCTGGTACGACTGGTATCTCTGCTCACTCCAGAACCGCCCGAGATCGACGCCGCCCCGCCCGATGACGGGGAAGGGAGGCACCGCGCCCGCCTCCCACAGCTTGAACCCGGTCGCGCAGATCAACACGTCGATCTCGTGCTCCACGCCGTCCGCCGTCCGTACCCCCTTCTTGGTAATGCACTCGATCGCATCGGTGACCAGGCTGACGTCGTCGCGGTTGAAGGTACGCAAGTAGTCGTTTGACATCGACGGGCGCTTGCAGCCTAACCCGTAGCGTGGGATCAGCTTCTCCCGAACGACCGGGTCATCGATCTGGCGGCGCATCCAGCGGCGGGTAGGAACCTCAAGCATCCGGCGGCTCGCGTTCGTCAGCCACTGTGGACCGACCCACATCCCGGCCATGCCGACCTCGGTTGCGACGGTTCCCACCAGGCGGATACCCGAACGGATTCGCTTACGCCCCAGAACCCACCGGATGGCGGACGTGACCTCCTTGTCAGGTTTTGGGAACACCCATATCGGTGTTCGTTGGAAGACTGTCAAATGTTCGACTTCGTCGACAATGGCCGGGACGACCTGCAGCGCCGTTGCGCCAGTGCCGATGACCGCGACGCGCTTGCCCGCCAGCGCCACGTCATGGTCCCAGAGTGCGGTGTGCATGAGCACACCCCCGAACTCGTCGAGACCCGGGATATCAGGCATCTTCGGGCGTTCGAGGCCACCGACCGCCATGACTACATTTCGGCCGGTAATCTCCTGATCGGCGTCGGTAGTCAATCGCCATAGGCTATTGCGCTCATCGAGCACCGCCGAGGTGATCGTAGTGTTCAGCCGCAACTTTTGAGCTAGGCCGTACTTGTCCACAAGGTCGCTGGCGTAATCGCGAAGCTCGTAACCCGGAGCGAAGATCCGCGACCAATCACCACGCTGCTCGTAGGAAAAGCTGTAGACAAACGAGGGAATATCCACCGCCACACCCGGATAAGTGTTCGCATGCCAGGTGCCGCCCACCTGATCCCACTTGTCGACAATCACGAAGTCGTGAATGCCTCTGCGTTGCAAGGAGATACCAGCACCGATACCGCCGAATCCAGCGCCGACGATCACGACTTCATGGTCTGGAGTGACACGCTCGACAGTCGGTAACTGCTCGATGTCGATCGTTGTACTCAACTTGAACTCATGGCCTTCCTGCTACTTGAGATGACCGACAAGGGCACCGTCGTCGCCGAACAGCTCCTGCCGCCACTGCTGCACCAGCGCGGTCGTGTCGATGTCGTCGGGATGGAAGCCCGGCTTTAGGTACATGCGCAGATCGGCCATCAGCCCCTGCACCAACGGGTCCCGGAACACCGCACGCGTTTGACGCGCCACTTTGATCGGGCGCCATCCCCGCGGATCGGCCAAAATAGACAACAGCACCCCGATCGACACCACCGGGATCGTCAGGATGTACAGCACCGCCATCACCCCGATCCGGAGCCACTCCGGCCCATCGACGGCCCGGTAGACGTCGAACGCCACCGACTTATGTTCCAGCTCTTCCACCGCGTGCCAGTTGAGCAGGTTTCGCACCTCGGGATCGCCAGGAATCTTTTGTATCTCTTCGCCCAGCATGCGCTCAGCCAGTGTCGCGGTGTAGTGCTCGGCCGCCGCCGTGACCGCCAGGGGTACCCGCGCTGGCAGCAGGTTCTCAATTCGCACGATCAACCGCTCCCGGCGGCTGTCATGCGGGAACATAAACAGCCGGACAATCGGGTAGCCCATCTCGATGAGCTTCTCGTTGAGCCGGCGGTGTTCCTGGCCGTGCACCGACTCCTGGCCAAATGAATCCGGCCACCCGCTTCATCAGTACCGGATCGGTCATCTGATCGGCAAAGCGCCGAACCGACCGGATAAACAACTCCTCACCTGGCGGAAACACGCCGGACAGCAACGCCACAAGGTGGCTGAACACGATATTGCCCTCAACGAAATGGTGGTCCATCGGCTCGGGATCGCCGAACCAAAACCGAATCCGCCGAGCCTTAGGATACGTACTCTCGGCTACTTTTTCGGCTGCTGTTCCGCTTTTCGCAGCCATTGCCTGACTAGCTACCATGGCAATCCCTTTTGTTGTGGATGTTCGCAATCACTTCAGGTAGCCGACGAGTTCTCCGTCGGTGCCGAAGAGTTCCTCTTGCCAGTGCTCCAACAACGCGTTCGTGTCGATGTCGTCAGGATGGAATCCCGGTCGCAGATATTTCGTAAGGTCTGGGATCAAACCCCGGAAGATGGGGCCACGGTACAGCCGATAGGCCTCCCGTATCACCCGTAGCGGCTGACGACGCCCATCCGGGTCGTGCGCCAGCGAGTAAACCAATGTGACGGCTATGAGGAGAAGCAGGGTCGGAATCATCACGGCCATCACACTCCTGCGCATCCGCTCCGTACCTCCCGCCACCGTGCGGAAGACATCGAATGCGACCGATTTGTGCTCAAGTTCCTCCACGGCATGCCAGTTCAGCACGTTCCACACCTGCAACTCGCCCGGAATCGCCTGGATTTCCTCTTCGCCCAGCGTGCGCTCAGCAAGTACGGCGGTGAAGTGTTCTGCAGCTGCTGTTACCGCCAGGGGTAGCCGCGCAGGCAGCCGCTCCTCCAGTCGCTTGACCCAGTCGTTAAACTTCTTCGAATCCCACCAAGCGATCGGGTAACCCATGTCGATGAGTTTCTCGTTCAGCAGGCGGTGTTGCTGTCCGTGGACCGATTCCTGGCCGATGAAGCCCGCCACCCGTTTCTTCAACGTGGGATCGGTGACCTCATCTGAGAATCGACGCACCGACCGAATAAACAACTCCTCCCCTGACGGGAACGCACCCGATAGGTTCGCCACGAAGTGGCTGAACACGATGTCGTCGTTGACGAAGTACTTGCCGTGTGTGCCGCCGTCGCCGCCAAACGGAAAGCTTATCCGTCGGGTCCTCGGATAACGGGATCCAGCGCTCGCTGCGGTCACCGACTTTGCCTCTTGCCTTGCGTGGTCACTCGCCATGAATGCTAGCCCCTTCCTTGAACGTGTGACGTGTAGTTCCAGGTACCAATAGTACTAGGTGTTGGAACCACGCTACTGCGGATCCACGAGGTCGGCAAGCATCCGGCAAGCATCACGAAAAGTGCCCGCGAAACGCCCTCGGTGCATCACGTAAGAATGCCCGCGAAACGGTGATCCCCGCCAGGCATGGAGAGTGGGCTGTCGATGTCGTCTCGTGCCGAGATCACCGCGAAGTTCGCCAAGGCGTATGTGAAGGCGTCGAAGGCGAATAAGGGGCAGATTCTGGATCAGGTGGTGGAGGTCACCGGCTGGTCGCGTGACAATGCTCGGCGCCGGTTGACGGCCGCGGCCCGGCCGCCGGGAGCGGGCCGGCAGGTCGCCAAACGACCTCGCCGGCAGCGCAAGCCGAAGTATTCCTATGACGCGCTGAAGGTGCTGGGCCACTGGAGCGAACGGCGACGTGCAGTGTCGGTTTGTCGTCGTCTGACTCGTCTGGGCGGGAGACTTGATCCCACATGGTGTCGATCATCGGTTGCAGGAAGAGCTGTCCCAGCTGTCGGACCATGATGTCGATGATCTGGGTGGATCCGCTTCGCTCCGCATTTGCGATACCGGCGTCGCGGGCTTTGATGAGCTCCGTTCGGGTCAGCTCTGTCAATCGCTGGAGCAGTTGGCCTTTAGACCCTGCGGGGTCCAGTAGCGCGCGGCGCAGATAGTTGACGACGGCTGGGTTCGATTCGAGCATCTCCTTCACAGCCACGTCACGCGCCGTGGCGACTTGTCTTGGTGTTCCATCAACGGGGACCTGCGCGATCGTCTGCGCGAAGTAGTCGACGACGAGTTGTTCAACGGCGCGGCGGATTCCGTCCTTGGTCTTGAAGTGGTGGACAACCAGCCCGACCGTGACGCCGGCTCTCGAGGCGATATTTCGCATCGACGTGCGGTCCTCCCCGAACTCCGCGAACAGGTCCATCGCGGCGTTGCGAATGCGCGCCTTCGCGGTCAGGTCGTCTGCGCCTGCGCGTGGATCGGCGAACGGTCCCATGCGTCTCCTTCGTTCCGGGCAAGTGTACAGTGAACATCACTTCTTGTACAGATAGGAAGCTTCCTGTACAGTCGTACGGTATCAATTGAAGGACCACATGGTGCAGGGCAGTCTGAACGGCGTTCGCATCGTGTCGCTTGCGGTGAACATCCCGGGCCCGCTCGCGGCGGCACGGCTGGCGCGCTTCGGCGCGTCGGTAACAAAGGTGGAGCCCCCTACCGGAGATCCCTTGGCCGCGGTCGCGCCCGGCTGGTACGCAGAGCTCGCCAGCAAGCAGACGGTCTTGGTTCTGGACCTCAAGGACGCCGGCGACCGCGCCAAGCTGGACGTCGAGCTGACTTCCGCCGATGTGTTGCTCACCGCCATGCGCCCTTCGGCGCTACGCAGGCTCGGGCTCGACGACGCGCATGTCAGGTATCCGGGGCTCTGTCACGTCGAAATCGTGGGCTACGACGGTGACCTCGAGGAGCGTCCTGGCCACGACCTGACCTATCAGGCCACGCACGGCACCCTGCAGCCCCCGTTGATGCCGGCGGTTCCGGTCGTGGACCTCCTGGGTGCCGAACGTGCCGTGTCCGGGGCCCTGTTGGCGCTGCTTGATAGGCCGAATTCCGGTGCCGGCCAACACGTCCGGATCGTACTGGCGGACGCCGCAGCCGACGCCGGCGCAGCCGTGCGGTACGGCGTCGCAGGGCCCGGCGACCCGCTCGGTGGCGCGACTCCGACCTACGGGATCTACGCCAGTGCCGACGGCTATATCGCCCTGGGCGCAATCGAACCGCATTTCCAGAAGCGGACCCTCGAGGTCCTGGGCGCAGCAGATACCCACGAGGATCTCGCACGAGTCTTTGCCGGACAAAGCACGCGCCACTGGGAAGAAGTCGCCGAGACGGTTGACATCCCCATCGTTGGAATTCGTACACCGGAACAAGGAGTGGAACATTGAACGCGCGCGAAGCAGTGATTGTCGGGGCGGTGCGCACGCCGGTGGGTAAACGAGGTGGCGCTTTGAGCCGGTGGCATCCGGCCGACTTGCTCGGTCACACCTTGCGAAACCTGGTGGAGCGCAGTGCGATCGATGCCAAAGACATCGATGACGTCATCGTCGGCTGTGCGATGCAGCATGAGCACCAGTCCGGAAATATCGGGCGGCACGCGGTGCTGGCTGCGGGTCTACCCGAATCGGTGCCGGCGGTCACCATTGATCGCCAATGCGGGTCCGGTCAGCAGGCGGTCAACTTCGCTGCATTCGGCGTCACCGCGGGCATCTACGAGCTGGCGATTGGGTGCGGTGTGGAGTCGATGTCGCAGGTGCCGATGCCTGCGTCGTTCATGCCGGGCGCGCCGCTCGGTCCGCAGTACTCGCCCGTGGAGTTGGCCCGCTACGACGACAACTTGGTGGCGCAAGGGGCGGCGTCGGAGTTGCTGAACTCCAAGTTCGGTATTTCTCGCGAGGAACTCGACGAATTCAGTATCCGAAGCCATGAGCGAGCATTCGCCGCGACCCGGGCGAAAAAGTTTCGCGCGCAGTTGGTGCCGATCACCGTCGATCCGCTGGATCCGTCGGCGGCGCCCGTCAGTGCCGACGAAGGAATCCGTGAGCAGTTGGATCCGGCGAAGATCGCGTCGCTGGAGCCTGTTTTCGCGGCCGACGGCCGCACAACCGCGGCCAATTCTTCCCAGATCAGCGACGGGGCAGCGGCGTTGCTGATCGCCGAGCGTGGCTACGCAGAACGCAGCGGGCTGGTTTCGCGGGCGCGGTTCCTGGCGATGACGGTCGCCGCGGCGGACCCGGTACTGCAGTTCACCGCGGTACTGGACGCCACCCACAGGGCGCTCGAGCGCGCCAACCTGAGTGTCAGCGACATCGACTTGTTCGAGGTCAACGAGGCCTTCGCCGGGGTGCCGCTGATGGTGCAACGCGAGTTCGGCATTCCCGATGACAAGCTCAACGTCAACGGAGGCTCGGTCGCAATCGGGCATCCGCTCGGGTCGACCGGGGCCCGCATGCTCACCGATCTGCTGTGCGAACTCGAGCGCACCGGACAGCGCTACGGCCTGCAGACCATCTGCGAGGCCGGCGGAACCGCCAACACCACCATCATCGAACGAATCTAAGGCACAGACATGGTCAGGGAAATCGTGAAGGGCGTGCCGTCGACGCACGGCGACCACTACCAGCTCAACACCACCAACCTGATCAGACATGCGGCGCGCACCTATCCCGAGCAAGAGGTCGTCTACCGCACCACGGAGGGCGACTGGCAGCGGTACACCTACGCAGACTTGTACGTTCGGGTCAAGCGGGCGGCGAACGCGCTCAGAGGAATAGGGATCGGCCCGGCCGACACAGTCGGAGTGCTCGACTGGAACAGCAAGCGGCACTTTGAGCTCAGCTGGGCCATTCCCGGCATCGCCGCGGTGATGCTGCAGATGAATCTGCGGCTGGCCACCGAAGACCTGAGCTACGTCACTGACCACGCCGAGGCGCAATGGATCCTGGTCGACGAGACACTCCTTCCGGTCGCCGAGGCGTTGGCTCCACACGTGCCGAAGGTCAAGGGCTGGATCGTAATGTCGGATAAGCCGCTCACCGAGATCGACACCACGCTGGAAAACGTCTTTCACCTCGAGGACCTGATGGCCGAGTCCGACACCGAGATCGACTGGCGGGTCATCGACGAAACCTCTGCTTACAGCGCGTGTTACACATCGGGAACGACGGGTCGGCCGAAGGGCGTCTACTACTCGCATCGTGGCAGCTACCTACACGCGATGGCGATGGCAGCAGCGATCAATCTCCGTCGCGAGGACACCGCGATGCTCATCACCCCGATGTTTCACGGCCAGTCGTGGGGGCTTCCGCACACCGCGATGTGGACCGCGGCGAAGGTGATCCTACCCGGCCGCTACCTGGCCGAGAACACGCAAATGCTCGTCGACGTGATGATCGCGGAGAATGTGACCGTCGCGAACGGCGCACCGGCGATTTTCCAGCCGATGCTGGACTACATCAAGACCCTTGCTGTGAAGCCAGATTTCAGCAGGACGAGACTGCTGTCCGGTGCGACCGAGCCGGCGAAGTCGCTGATGCGCGATTTCCACGAGCTCACCGGCGCCGATTTTGTGCAGGGCTACGGTGCGACCGAGACGACGCCGCTGATCACGATGAACATGGGCATCAAACCGTCCCTGCAGGGCACGATCACCGACGACGAGAAATGGGATTTCAAGCGTTTTCAAGGGCTGCCCGCTTCCGGTATCGACATCCGGATCGTCGACGACAACGGCAATGACCTGCCGCACGACGGTAAGAGTGTCGGCGAGGTACTGATGCGTGGGCCCTGGGTCATCGAGCGATACCACCAGCTCGACGACGACGACAACGCCGACCGCTTCCTCGACGGTTACTGGCGCAGCGGCGATGTCGGCACAATCTACCCGAACGGGTATCTCAAGCTCACCGACCGCCTCAAGGACGTAGTCAAGAGCGGCGGTGAATGGATTTCCTCTATCGATATGGAGAACGCCATCGTCGGACATCCGCTGGTGAAGGAGGCCGCGGTTGTGGGGATCAGCCATCCGAAGTGGCAGGAACGTCCGCTGGCCATCGTCGTGCCCGTCGAAGGTGGCGTGCTGACCCGCGATGACATCGTCGGTTGTCTGCAGGGGCAGTTCGCCAAGTGGCAGATGCCCGACGCGGTTCTCTTCGTCGAGGCGTTGCCGCGCACCAGTGTCGGCAAATTGGACAAGAAGATCCTGCGGGCCGAACACGCCGACGTTTACCGGGATGCGGTCACGTGAACAAACAAATTTTGCGATCGACTCGCGACGGTGCGGTGGCCCTGCTGGAGATCAATCGCCCGAAGTCGAAGAACAGCCTCAACGACGAGCTGTTGGGCGCGATGGGGGCCGAGCTGGCGGCGTTGCGGTCCGACACGGCCGTGTTGGCCGTGGTCATCGCGGGCGCCCACGGCATGTTCTGCGCCGGCGCCGACATCACGGCGTTCGACGAGATCCGGGCCCGGCCACTGGTCACCGGAGAGTCCAATGAGAGCTTCTGGTCGATACTGGCTGCGTTTCCGAAGCCGGTCATCGCCGCGGTCGAGACATACGCACTCGGGGGCGGCTGTGAGCTGGCGTTGGCCTGCGACATTGTCATCGCCGGCGAGTCGGGCCAATTCGGACTTCCCGAGGTGAAGATCGGCGCAATCCCTGGCGCTGGCGGAACTCAACGCCTCATTCGGGCGATCGGCAAATCCAAGGCTATGGCAATGCTTTTGACGGGCGATTCCATCAAGGCCCAGGAGGCGTGCGATGCAGGGTTGGTAGCCGAAGTCGTCGCCGACGGCGAGGCCGTGCCACGGGCGCTGGCGATGGCGCAACGGATCGCGACGAACTCCCCGCTAGCGGTGGCGCTGGCCAAGGATGCCGCTGTGCACGCGTTTCAGACATCACTGACGCAGGGACTCGAACACGAGAAACGGAATTTCTACGTGGCGGTGCATTCCGCCGACAGTCACGAGGGCCAGGCGGCATTCCTCGCCAAGCGCGCGCCCCAGTTCACCGGAAAGTAGGTAAAGCATGCCCGGACTCTTATTCCCGGACTACGTCGTTCCGTGGGAGACCGAGGATCAAAAACTCCTGCGCAAGCACGCCGCCGAGTTCTTCCGCAAGGAAGCGACTCCCAACCAAGCCAGGTGGGCGAAACAGCAGAAGGTGGACCGAGAATTTTGGAACAAAGCCGGCGCTGCCGGGCTTTTGGGCCTCGACCTGCCCGAGCAATACGGCGGTGGTGGCGGCAGTTTCGGTCACGAGGCGGTGGTGATGCAGGAGCGCGCCTACGCGCACGACACCGCGTTCGGTTTCTCCGTGCATTCGACGCTGGCTTCCCACTACATCGCCGAGTATGCCTCCGAGGAGCAGAAGAAGCGCTGGATCCCGAAGATGGTCAGCGGGGAGATGGTGATCGCCGTCGCGATGACCGAACCGGGCACCGGGTCAGACCTGCAGTCGATTCGCACCACCGCGGTTCGCGACGGCGACGAGTACGTCATCAACGGCTCGAAGACCTTCATCTCCAACGGTTCCCACTGCGACCTGGTGGTGATCGTGGCCAAAACTGAGTCCGGACTGTCGCTGATGGTGGCCGAAACCGAAGGGCTGGCGGGTTTCCAGCGCGGCCGGGTTCTGGAGAAGGTCGGCCAGCACGGCCAGGACACCCGGGAGCTTGCGTTCACCGACATGCGGGTGCCGGCCGCAAACCTGCTCGGCGGCGTTGAGGGCAAGGGCTTCGCCCAGTTGATGGAGCAACTTCCGCGCGAGCGGTTGACCATCGGGGTCGAGGCGATCGCGATGGCGGAGGCGGCGGTAGTAGAGACGATCCGTTATGTCAAGGAGCGCACCGCGTTCGGCAAGCCCCTCCTCGCCTTCCAGAACACCAAGTTCGTGCTGGCCGAATGCAAGGCGGAGGTGCTGGCCGGCAAGGCGCTGATCGACTACTGCACCGGCCGGTACCTCGACGGAAAACTCGATGCCGCAACCGCATCGATAGCCAAGATGTGGGGATCTGACAAACAAGTAGAGGTCACTGACAAGTGCCTGCAGCTTTTCGGTGGATACGGCTACATGATGGAATACCCGATCGCGCAGATGTATGCGGCGGCTCGGGTGCAGAAGATCTACGGCGGCACCAACGAGATCATGAAGGTGCTGATCGCGCGAAGCCTGTAGACAGACACACAAAAGGAGCAGCCGAATGGACATCGCAGCTAGCAGCGCGGTCGTCACCGGTGGCGCGTCCGGGCTCGGTTTGGCGACGGTGGAGACGCTGGCGCGGTCCGGAGCGCGGGTGGTCGCCGTCGACCTGCCCAATGCAAACACGGACGCGCTAAGCCTCCTCGGCGACACCGTCCGGTTCGCGCCCGCCGACGTCACCGACGAGGATGCAGTGACCAGGGCCATCGAGATCGCCAACGCGGACAAGACATTGCGTATCATCGTCAACTGCGCCGGCGTCAGCGATGGCACCAAGACCGTCAGCAAGAAGGGCCCTTTCCCGCTCGACGCGTTCGAGAAAGTAATCAAGATCAACCTGATCGGGACCTTCAACGTCGTGCGCCTGGGCGCATACGCAATGTCGCAGAACGACCCCGTCGGCGGCGAGCGTGGCGTGATCGTCAACACTTCCTCCGGCGCGGCCTTCGACGGCCAGATCGGGCAGGCGGCCTACTCCGCTTCCAAGGGAGGTGTGATGGCGGCGACGCTGCCGATCGCGCGTGATCTGTCGTCGTACTTGATCCGGGTCAACACGATCGCTCCGGGGCTGTTCGAAACCCCGCTTCTCAACTCACTTCCAGAGGCTGCGCTAACCGCTCTCAAGGCGCTGACGTTGCACCCAAACCGACTCGGTGATCCTGCCGAGTACGCACACCTGGTCGTAGCCATCGTTGAGAATCCGATGCTCAACGGCGAGACGATCCGTCTCGATGGCGCAGTACGGATGCCTCCGAGGTGATGTCCGGCCGTCAGAGTTGCTGATTGGATCCCACAACTCCAGGAGAGAATCAACGTGCAGGACAGTGTCCGCGTCGTCGTCGACCATGTGAACGAACACGGAAAATCGCGGCTGAGCGAGCGGCGGGTGGTGGCATCGGTGGGCCAGGCACTGCGTTGCAAGATGCGCAACGAGCGTGAACGCAGTTTCGTCTTCGTCACTCCGAGTCGGAGTCGGAGAGAGAGAGGCTTAGTCACGTTAGCCAACAGTCGACGAGTTCCTGAGCCCACGGGTATCGCCCGTTAGCCCTTTCAACGCCTGGAACAGCCGTTGTTGGCGTGTCCCTCCATCAAAACTCTCTGATGAACCGGCATCATTCTTGCTGACTGAATAGTTGATCAGATGATGTTTCTTCACTTTAGGTGAAGTCGAGGAGGCGTGGGTTGGCTCTGGCTGTGGTCCGCGATCTGCGGGAACATCGAGTACCGGCGAGCGAGGAGGAGCTTGCCGACTTCGAGACCGATGTGTTGGCCGGGTTCGTGCTGGCACGGGCGTCGGCCGGATTGGTCGACAGCACGATCCGCAACGACATCAACCACCTCGAGCTGATCCACGACTGGTTCGGCCGGCCGCTGTGGGAGATGCGGCCCGCCGATGTCGACGTCTATTTCGGCAAGGTGCTGCGCGACGCCAACCCCTCGACTCGCACCGGGCGGGCGGCGGCACTGACCGTGTACTTCCAGTTCTTGGAGCTTCGGCACAAGATCGACCTGCACAACATGACAGGTCGGGTCGTCGAGTGCCCGCTGGACGAGATCAACCGGCCGCGAGCCTCGGTCGATCCGCAGCTGCGTATCCCTCCGACCGCCGACGAGGTGGAGCAGCTGTTCGCCGGGTGGCGCCAGGAACTGGCTGGATTCAATCGGTCGTTGCAACACCTCGATTCCTCGGAGGTGTGTGGTGGCGTATGGGAAGCGGCAGTTGGAGGTTCGTGCGTATCGGGGGCAGATGCCCTCCCCGGGGCGGCCGTCGGTGGCCTGGCGGCAGGACAGGGTCCGGTTCTGGGCGGGGATCGCTGCCGGAGCGATGACCGAGGACGCCGCTACCGAAGCGGGCGTGTCTTCGCCGGTCGGGTTCCGCTGGTTCCGCCATGCTGGCGGCGTGAATCCACGCTTGCCAGAAACTGTTTCGGGCTGCTACCTATCCTCGAATGAGCGCGAAGACATCGCTTTATGGCGTGCCCATGGTGCCGGAGTGCGCGAGATAGCCAGGAGGCTGCGCAGGGCGCCGTCGACCATCTCGCGTGAGCTGCGCCGTAACGCCTCGACGCGCACGTATCGGCTCGACTACAAGGCCTCGGTCGCGCAGTGGCATGCCGAAAGGCGGGCGAGGCGCCCGAAGACGGCCAAGCTGGTCGGCAACGACCGGCTGCGCCAGTACGTCCAGGACAAGCTCTCCGGTGTCGTTCGTGGCGCTTACGGGCAGATCATGGCTGGTCCGGCCGCGACGCCGTGGAAGGGACGCAACAAGCCGCACCGAGGGGATCGGGCCTGGGTGACAGCATGGAGTCCTGAGCAGATCGCCCATCGGATCAAGCTTGACTTCCCTGATGATGAATCCATGCGGATCAGCCACGAGGCCATCTACCAAGCGCTCTACGTGCAAAGCCGCGGTGCGCTCAAGCGGGACTTAATCACCTGCCTGCGCCGGGGTCGGGCATTGCGGGTGCCGCGGGCACGGTCTCGGCAGAAAGCGTGGGCGCACGTCACGCCGGAGACGTTGATCAGCGCTCGGCCGCCGGAGGTCGCTGATCGCGCGGTCCCGGGACACTGGGAGGGAGATCTGCTGATCGGGTTGCAGCGCAGCGCGATCGGCACGCTGGTCGAGCGCAGCAGTCGGTTCACGATGTTGATCCATCTTCCGCGGGAGGCCGGATACGGGCTGATTCCGCGGACCAAGAACGGGCCGGCTCTGGCCGGCTACGGCGCCCTCACGATGGCCAACGCCCTAGCGCAGACGATCACCTCGCTGCCCGAGGAACTGCGCCGGTCGCTGACCTGGGACCGGGGAAAGGAACTGTCGGCGCATGCCCAGTTCTCGATCGCCTCCGGGGTCAAGGTGTACTTCGCCGACCCGAAGAGTCCGTGGCAGCGTGGCACGAATGAGAACACCAATGGCCTGTTGCGCCAATGCTTTCCGAAGGGCACCGACCTATCCCGGTGGAACGCCGACGACATCGCGGCGATCGCTCACACCCTCAACACCCGACCACGCAAGACCCTCGGATGGCGCACCCCGGCCGAAGCGTTCAACGAACACCTACACTCACTTCAGCAAGCCGGTGTTGCAACGACCGATTGAATCCAGCCTGGTCACCTGCCGCAAGTTCGCCCCGGCCGCCCGCAACTACGCGGTCGCCCGGCTGGCGGCCGACGTGGGACTGCGCATCAACGAGGCGCGGATGCTCGACCTCGACGATGTGCGGTGGGAGCTGGGGCGGTTCGGCAAGCTGAACGTCCGTCACGGCAAGGGATCACGCCGCAAAGGCCCCAAACCGCGACTGGTGCCGCTGATCAACGGCGCCGACCGCAGCCTGAGATGGTTCATCGAAGACGTGCTTGGACTGTTCGATATCGACCCGAATAGCCATGCCGCGCCACTGTTTCCGTCCGAACGCAAGAACATCGACGGGACGTGCATGCGCGCGACAGCTGACGTCTATCGCCGATCGTTGGCGGAGGCGGCGGACCGGCATCTGCCTGCGTGGTCGGGGAAGCTGACCCCGCATGTGCTGCGGCACTTCTGCGCGTCCCAGCTTTACCTCGGCGGAATGAACCTGTTCGCCATCCAGGAATTATGTGGTCACGCCTGGACGGCCACGACGGCTCGATATATCCACGTCCACGCCACCCACGTCGAAGATGCCTGGGTCACAGCACAACGTAACAACACGAAGTAACTGCACCTACGAACTTAAGGATTGGCTCAATGAAGTGGAATCTACGCCTGACCGCGGCCAACCGCGGCATTTGGAAGGCCAGCGAACTCCAACGGATGCTGGCCGAGCGCGGCCTGGTGATCAGCGCCGGCAAGATGTCGGGCTTGTGGTCGGGCAACCCCAACGCCATCAAGCTCCACGATCTCGATGTATTCTGCGCCGTGCTCGACTGCGCCATCGACGAACTGCTGATCCCCGAGCCCGAAACCGTGGCCGCACCCACGCCGAAGGGTAGCGAGGAGGCCGCCGCTGCGGCCGGTGAGGCACGTCCCGTCACCCCGCGCGCTCGGACGGGAAGGTCGCTGCCGCCGCGATGAATTGCCTGCAATGCGGAGCCGAACTGCCAGCCAACGGTCGCCGCGACCAAAAATACTGCGGCAGAAGCTGTTCAAAAAAAGCGCACTACTATCGCGGAAAGGCGGGACTGCCTGCTCGCCCGCCCCGGCGGCATCCAGCCTTGGAATCCGACGACCCCGTGCTCGTGGCCGCTGCGGTATACGCCCGGGAACGCGCTGCCGCCCACGATTGGTGCGGTGAGACCACAAACCGATGCCTCGACGCCCTGGTCACCCTTCTGGCCGGTCGGCCCCCCGGTGATCGCGTGCCGCTCAAAGAGGTTCGAACACGGCCGCATCGGCTCGCGTCCCGTCGCAGGCTTGTCGAAATCCTCTCCCACTTCGACCTGCTGACAGACGACACCGAACCTCCGATCCGTGCCTGGATCGACCGCGTCACCGCGGAACTTCCGCCAGGGTTCGCCGAGCCGTCGCACCACTGGCTCCTTACCCTGTTGGTCGGCGGCGCACGTGCTCGCCCACGATCGCCCAGGACCCTCTACAGCTACTTCGGCGCGGTCAGGCCCCTTCTCGCGCACTGGTCCACCTCCTACGACCATCTCAGGGAGGTCACCAGGGCCGACGTCGACGCGACGCTGCGGCCGTTTCAGGGAAACCAGTGCCACAATCTGATCAAGGCGCTGCGGTCGCTGTTCCGGCACGCCAAGAAGAATGGTCTGGTCTTCAGCAACCCAACAGCGGGTTTGAAGAGCCAACCAGTAGACCAAGACCTCGTGCCCATCACCGATGATGAGGTGCGCTCGATCGAACAGCTCGCGAGCGAACCGCGTGCACGCCTAGTTGTGGCATTGAGCGTCGAACATGCCTGCCGCACAAGCGTTATACGCAAACTGGTGCTCGACGACATTGACCTGCCGAACCGGCGGATCACCCTTGCTGGACAACCAACGGCTCGGCGAGCTCACCCACAGAGCGCTGATCACATGGCTCGACCACCGCCGGGACAGATGGCCCCACACTCCGAACCGGCACGTTCTACTCACGACGAAAACTGCATTGCGCACAACGCCGGTGAGTCAAACATCGGTGAAACAATCGTTGAGCGACAATGGGTTCACGATCGAACGCATCCGTGCCGACCGAATCCTTCACGAAGCGCTGACCGCAGGCCCCGACCTGCTGCATCTGTCTCTCTCGTTTTCGGCATCTCCCACAACACCGCGCGGCGCTACACCACCGCGAGGGAGTATCCGAAATTCGGTGTAAGTGGCCCGACACGCCGGGTGTGAGCCTGGCGGGGAAGGTCCACGATGACCGAAACGATGAGGGCTGTGACAGCAACAGCCGATGTCCACGATGATGAAGTGATGGTCAGCTCTCCGACACCGGAGGAGCTGGCGACGGCCCGCGAGCTGGTGCGGGCGGCCCAGGCCCGCGGGGTGTCGTTCGCCGATACCGCTGACGGGGTGCTTAAGGCGCTGACCAAGACGGTGGTCGAGACCGCGCTGGAAGAGGAGCTCGCCGATCACCTCGGCTATGACAAGCACGATCCGGCCGGGCGGGGGGCGCCGAATTCACGCAACGGCACCCGCACCAAAACCGTGTTGACCGACACGGTCGGACCGGTCGAGATCGCCGTGCCCCGCGACCGCGGCGGCAGCTTCGAGCCCCAGATCGTCAAGAAAGCATCAACACCGGTTGACCCGGGTCGATGAGATCGTGTTGTCGTTGTATGCCAAGGGATTGACCACCGGGGAGATCGCCGCCCACTTCGACGAGCTCTACGACGCCAAGATCTCCCCGGACACCATCAGCAGGATCACCGACAAGGTCCTGGCCGACATGGCGGAGTGGACCGCGCGGCCGCTCCGTCTACGCCGCAATCTTCATCGACGCGCTGAGCGTGAAAGTGCGCGACGGTCAGGTCGCCAACCGACCGTTCTACGCCGCGATCGGGGTCGATCTGGCCGGGCACAAGGACGTGCTCGGACTGTGGGCCGGCGACGGCGCCGGGGAATCAGCCAAGTTCTGGTTCGCCGTATTGACCGACCTGCGCAACAGAGGCGTCACCGACACGTTCTTCTTGATCTGCGACGGACTTAAGGGGCTGCCCGACGTTGTCGGTGAGGTGTGGCCGGCCACCATCGTGCAGGCCTGCACCGTGCATCTGATCCGCAACAGCTTCCGCTACGTACCGCGCCAGCACTGGGACGCCCTGCGCCGCGATCTCAAACCGATCTACACCGCCCCGACAGCGGCGGCCGCAGAAGCGGCGCTCGAGGCGCTCGCCGACCGCTGGGGCAGCCGATATCCGGCCCTGATCCGACTGTGGCAGTCGTGTTGGAATGAGTTCATCCCGTTCCTGGATTACGACACCGAGATTCGGCGGGTTCTGTGTAGCACCAACGCAATTGTTATCTGGAGTCCTCCGGGCGGTGTCCTTGATGTCCGACACGAGGCGTTCAGATCCCAGGTTCTGCGTGGTGGACGTGATTATCTGCAGTCGTCCAGGAGGCAAGAACCTGCGGAGGGACGATGCAGATTGCGGTCAAGTCCAGGGACGTGGTGTACGACGTCGTCGTGTGATTCTTCGACTTGGTGGTTTAGGCGGTCAGTGCCGCCGGGGTGTCCTCCTGTTCTGTTGATGGCGTGTGGTCGGCGCGGGATTTGCTGAGGACGTCGAGGCCGAGGTAGCGGCGGGATTCGGCCCATTCGTCGTGTTGTTCGGCCAGCACCGCGCCGACGAGGCGGATTAGGGCGTTGCGGTCGGGGAAGATTCCGACGACGTCGGTGCGCCGGCGGATTTCCTTGTTGAGTCGTTCTTGTGGGTTGTTGGACCAGATCTGCCGCCAAATTTGTTTGGGGAAGGCGGTGAAGGCGAGCAGGTCGGCGCGGGCGTCTTCGAGGTGGTCGGCGACCTTGGGGAGCTTGTCGGCCAGTGCGTCGATGATGCGGTCATATTGGGCTGCAACGGAACCGGCGTCAGGTTGATCGAAGACCGAATGCAGTAGTGTGCGTACCCACGGCCACGATGATTTCGGAGTGATGGCCATCAGGTTGGTGGCGTAGTGGGTGCGACACCGTTGCCACGATGCCCCAGGCAGGGTGGCGCCGATCGCGGCCACCAGACCGGCGTGGGCGTCGGAAGTGACCAGACGGACCCCTGATAGGCCGCGGGCGGTCAGCGACCGCAGGAAGGTCAGCCAGCCGGCCCCGTCCTCGGCGGTGGTGACGTCGATGCCCAGGATTTCGCGGTAGCCCTCGGCGTTGACCCCGGTGGCGATCAGCGCGTGCACGTTGACCACCCGGCCTGCTTCGCGAACCTTGAGCACCAGGGCGTCAGCAGCCATGAACGTGTACGGGCCTGCATCCAGTGGCCGGGTCCGGAACGCCTCGACCGCGGCGTCGAGCTCTTTGGCCATCACGCTGACCTGGGACTTCGACAAGCTGGTGATGCCCAGAGTCTCGACGAGTTTGTCCATCCGCCGCGTCGAAACGCCCAGCAGGTAGCAGGTAGCCACCACCGTGGTCAGGGCCCGCTCGGCGCGTTTGCGCCGTTCCAGCAGCCAGTCCGGGAAGTACGAACCTTGCCTTAGCTTGGGAATCGCCAGATCCAATGTGCCTGCGCGGGTGTCAAACTCGCGGTGCCGATACCCGTTGCGGGAATTGGTGCGCTCGCTGCTGCGCTGGCCGTAGCCGGCACCGCACACCGCGTCGGCTTCGGCGCCCATCAGGGCGTGAATGAAGGCGGCCAACAACTCGCGCAGCACATCAGGGTGCGTGGTGGTGAGTCGTTCGGCCAGCACGGCAGACAGGTCGATATCGTGGGCAATGGTCATCGCGTTGATTCCTTTGCTCGAGTGACTTTGGTCGGTCCCTCGAAGAATCACGCGATGACCTTCATTCATCCGGCTACGACACGCCGGTCATCACCGGCTCGTACACCACTCTGCTGGACGCAACTCAGATTGCACGAGTTATCTCGCCGGTCTCGTTGCGTGAGTCGTGGACCGTTCTCGGCGACGACGATGCTCCGGTAGCGCCGGTCGACCGGTATCTGGCGTATCTGACCGACATCGAGCGATCACCGAACACGGTCAAGGCATACGCGCACGATCTCAAGGACTGGTTCGGTTTTCTCGCCGAGCGTGGTCTGGACTGGCGGGGCGTTCGGCTCGACGATCTCGGTGAGTTCGTGGCCTGGCTGCGGCTTCCGCTGCAGGCCCGGCATGGGCAGGTCGCGGTGTTGCCGTCGGTGCCGCATCATTGCACGGAATCGACTGTAAACCGCAAACTTTCGGCCGTCGGGGCGTTTTACACCCACGCTGCACGAGATGGGGTGGATGTCGGTGAGCTGCTGACCTCGTGGCAGGTCGGCGGCGCGCGCGGCGGTTGGAAGCCGTTCCTGCACCACATCAGCAAGGGCACGCCGAGGTCGAGGCGGGTGATCGCGTTGAAGACGCCGAAGAAGCTGCCGCGGGTGCTGTCGCCGGACGAGGTGCAGGCGATCCTGGACGGCTGCGGCCGGTTGCGGGACCGATTGCTCTTCGCCGTGCTCTACGACACCGGGATGTTCTCCAGGGCTCGGCCCCCGTGCGCCAGCGTGATTCTCTGAGTTTGTGCAGCTCAGAAGCTGATGTCGGAGATGCTATCCACCGCAACAGGTGTGGTGCAAGCAGACTCGCGCGTGTCATCGCAGCCGGGTTGGTGTGTTGAGTCGGGCCATGAGTTCGCGGTTGGCCGCCCGGGCTGCGGCGAGGTCTTCCTCGCGTTCGTCGAGTTGTTGCTTAAGGTCGAGGTTGTGCTGCTCGAGCTGGCTGATGCGCTGGTGGAGGGCGTCGATATCGGTGCGGGCGCCGAGCCCGGACTCGCGCCACGTCTGTTCACCGAGCGCTTCGGACAGCCGCTTCTCCAGCTGCTGGATGCGCGCGCCGAGCCGGGCGGCGCGTTCGTGGGCAGCGAGCAGATCGGCCTGCAGTGAGGCTCGGGTGACCCCAGGGCCGGTGTGCTCACTCGGGACTGGATCTGCTTGCAGCGCATGGATTTTCTCGAGCAGGTCGGGGTGTCGGTAGAGGAATGTGCGGTCAACGGCGGCGGCGCGGGCGATCGCGGTGGCGCTGAGCCGGTCGCCGGCGGCGGCGGCTTGGTCGATCGCGGCCAGCACGCGCCGGCGTCGGCGCATCGAGTCGTCGCGCCGGCCGTCAAGCATCGATCGGGTGCGTGTTGTCGACGAGACGGATTGTGCGGGTGTGTGATTCGACGTGGTAGCGGTGGTGGTCATGCGGTGGCCTCCGAGGCGATGGTTGTCGGTGCGGGTGGGGTGAGGCTGGGCATGCCCAGCGGGACGGTGTGGGCCGCGCGGTGACGGCGCACGATAGCGATCGCGTCGTCGATGCGGGCTTGCTCGGTCTCGTTGAGGTCGGCGACGTCTGCTTTGATGCGGTTGATCAGCCGCCGGATGCGGGTGATCTCCTCGTCGGTGGGGGTGGCATCGGCGCGGGCCCAGTCATCGACCCCGTCGATGGTGGCGGCCAGCCGTTCCCGGGTGCGTAGCAGATCATCGAGGTAGGCCTGCAGGTCGGGCAGGAACGCGATGTTGGTGCGGAAGTGATCGCAGCCCACGCAGCGGAACCGGACCGGGCAGGCCCCGCCGCCGGCCTTGACGTTGGTGGGTTCGGTGCAGGTGCCGTAGGGGACGGCGACCTCGCCGACGGCGTGGCGGGCGCGTTCGGATTCCAGCAGCATGCGCGCGTCACGCCAGATCCGGTTGCCGTGCCGGTCGAAACTGAGCGCGGTGACGGTGTCGACGGCGTCGCGGCGACGGTCCTCGCCGATGCGGTAGTAGCGCCGGGTCATGGAATAGCTACGGTGATCGAGCAATTCGGCCAGAACGTCGATCGGCACCCCGGCATCCGCGTGACGTTGGGCATAACAATGCCGATAGGCATAGGGCGTGACCTTGGTCTTGTCGACCTCGACCCCGTCGCGGGTGCGCAACACGGGCAGGGTCGAGATCCACTCGCGGTGCCGGTTGTCGAGCGTATCGATGCTGATCGGCTTTCGCCCCTCGGGGTTGCGGCGTGGTGTGGGCAGCAGTGTCAGTTCTGCGGGCGGGGTGTGAGGAAACATCGCCCGCACCCGGTCCTGCTGAGCGGCAATGACTTTCGCGGTAGCTTCGCCGATCGGCACACGCCGTCCGAGACGGTTGGCCTTGGCGTTGTCGTAAACCAGCACCGCCGATCCGTCCTTGTCGCGGTGCAGGCAGTTCAACGGCAAGGCGAGAATGTCCTCGGGCCGGCGCCCGGTGTCGATGCCGATCTGGGTGGCGACCCGCACCTCGACGGGTTCGAGGGCATCGAGGTGGGCGCACAGGATGGCCAGGACCTCCGGTGGCAGGTCGCGGCCGGGTTCGCCGCGTTCGGGTTCGGCGGGGATATCGCCGCGCTCGATGGCGAAATCGCCGGCCAGTCCGGCGGCTGTCTGCCCCGGCCGGGTCAGGCCGAGGGCGCGGATCCCGGCCAGCACCTCGCGCATGTCACGGCAGATGCCGTTGCGCCGGTATCGGCTGATCTCGCCGACGGACTCCAGATAAGCGAGTCGGTTGAGGAAATCCTCGATGTCGCTGCGGCCCAACGCCGAAGCGACGAGTCCACCATCGGGTCTGCGGCCGAGGAACTCCGACAGCAGCCGCAGCGCGTTGATCTTGCCGCGCACTCTCGCGGCGCCGCGACCTCGGTGGCGCGGGAGTTGTTCTGCTGCCCACCGCTTGACGGACTGGGCCAGCCAGGCCTGGCCGATCCCGGTGAACGACAAAGACCCGCGATGGCCGAAGACCGCGAGATCCCATGTGTCCTTTGCCTGTTCGCTGCCGGGATCGGCCAGAGCCCGCCGGACGTGCTGGGTCAGGGCGCTCCGCAGCGACCGCACGGACTTGTTGCGGGTGATCTCGGCCCGGTCGGTGGTGATCGAGGCGGCCTGTCGCCGGCGCAGCCCGTCGCAGAGCACCCGCAGCTCTACCTCGGTGATCTTCGCCCCGCCCCGGACGCGCTGCTGAACGCCGAACAGCACCTCGACCACCACCAGCACCGGCAGCGCGCGCAGGTTCACCCGCCCGCACTCGGCCACACCCGATTCCTGGGCTTGCCACCGATGCGAATCGAACTCAGGGTTGGTACCGAGCGCGCTACGCCAGCGCTGGTAGTGGGTGTTGCAGTAGCCGCGCGCGCTGTCGGCGGGCCGGGTGCACGCGGCCACCGCGCACGCGGGCATCGGCGGCAACGGCCGCACTCGCGGGTCGGCCAGGAACTGCTGCATCGACACCGGCGGTCGCCGCAGGCGGAACTTCTTGGCGTGCGGCTCGCACAACACCGCGTGCCGCACCGTCGGCACACACCGGCATCCCGGCACCGCGCACCGCGTCGCGGACGCGGGTTCGGCGGGCAGGCATGCGGCAGCGGCGATCTCGGCCGTGTTCATTCCCCGCCGAGTCAGGCGCGTGCAGCACCGATGACACACCGTGAGACCGGATTGCACGGTGTTCTGGCATCCCTCGGCCCGGCACACCGTCCGGCCCAACAATCGATGCTCCGCGAGCAACGACAACACCCTGGTCCGCGGATCCCACCCCGCCTCGTCCAAGAACCTGCGGTCGAGCATCCTCGCCAGCCGCGCGGCCGTGCCGATCACCACGACCCCGTCCAACACGTGCGGGGACTCGCCGCAGTCCTGCTCGACCGCGATTCTTTCAGCCAGCCCCACGGCGGTCACCGGGTCACCTGGGCCTGCTCGCGGGGACTGGGCACCGCATCCACGGCGGCCCGCAGCCGGGAGGAGTCCGGATGCAGGTAAACCTGCGACGAGGACACCGCGGCGTGGCCCATCAGGTCGGCGACCACATCGATCCCGGCCCCGGCATCAACAACGTTGCTGCCGAAGGCATGTCGCAACTGGTGGGGCCGCACCGCGACGTCGAGTCCGGCCCGCCGGGACGCCGCGGCCATCAACTCGCCGATCGCATCCGGCCGCATCGGCGCACCGATCCTGCCGCGGAACAGGTTAACGAACACGAAGTCACTGTCGGCGGCGCCGGTGACACGCATGCGTTCGAACTCGTAGACGTCGAACAGTTGCACCACAAGGAAATCCAGCGGCACCACCCGCTCCCGCCGCGACTTGGCCCAGGCCTGGTTCGGGTTGTCGTCTCGGCGCACCACATGCAGATGCGCGCGCTCGACATCGCAGCCCAGCCGCCGCGAGTCCACCAGCAGGTGCACATCGCTGCGCCGCAGCCCGCACACCTCCCCGCGGCGCAACCCGCCCCGCGCCATCAACAACACGATCAATCGGTCCCGCGCCGACCGGCACGCCCGCAGCAGCGCGACGATCTGCTCGTCGCTGGCCCGATCGATCGTCGTCTCCGGTTCCCGCAGCCGATGCCGGGCCCGCATCCGCCACGCCATCCGCCCGTCCTCGCCGCGGGCCTCCGCCGGCAGGTCCCGGTCATCGGCGACCTCATACAGCATCGACACCAGCCCCGCCGCGCCGTGGCCGGTCGCCACCGCGTGCACCACCATGCCCCGCACCGCGGTCAGCACCCCGTTGATCCGCGACGGGCCCCGCACCGCAGCAGCGCCAGGTCCGGCCACCACCACGCTCGCGGCGTCATCGACCGATGACCGGGCGTGAGCCAGCCACGTCATGAACAACGCGAAACCCTCCACACCGGCCTGCCAGGACCGGCCCGACCGGGCACACCAGCGCAGGAACAACGCGATCGAATGCGCATACGCCTTCGTCGTGGACTCGGCCGCGTCGTGGCCGAACCGCAGATGCCGCAGATACGCATCGGCGACATCAACCACCTGCAGGTCCTCATCCAGCACCGTCCAATACCGTTGCCCGGACGGCAAACTCACCGGGAATACTCGCATGGGCTCTCACTTTCGGGCCGACAGTCACAAACAACTACCAGCCACGAGCACCACACCCCCGGAGAAACGCCGAGCAACCCGCCCGATCATGTAGATCGAGCAACGTCCCGCAACAGGTCAGGAAACCCCGGAGAAGGGATGCGGATCGGCGAGGTACTTGGTTTGCGGCACAACGACATCGCCTCCGCTGAGCATGAAGTAACGGTGCGGCGACGCGACAACGCCAATGGCGCGCGCGCCAAGTCACAGACCGTCCGCACGATCCCGGTCAGCAGCGCGTTGATCCGATTGTTCGCCGACTACCTTCACACTGAGTACGGCGATCTGGACAGCGACTATGTGTTCGTCAACCTGTGGGGCCGTCCGCAGGGGCATCCGCTGACCTACGCCGCGGTCTATGACCTGGTGCGGCGGCTGCGCCGGCGGACCGGGATCGACTTCGACCCGCACTGGCTGCGACACACGGCCGCAACCCGGCTGCTGCGCGACGGAGTCAGCATCGAGGTGGTCGCGCATCTGCTCGGACATGCGCACGTGGCGACGACGACCACGACGTATGGGCACCTCACCGTGGAGGACGCTCGGCGGGTCATGGAACAGGCCGGTTGGTTCACCGATGGGCAGGTGCGGCTGTGAGGGCGCCGTCGCTCAAGCCTGCCGGCCCGTCGGGGCTGCTGGGCAAGCTGATGGCCGAGGTCCGCAACGAATTCCGCAGCAATGTACTGGAATTCGGGCCCGAGGATCCGGTGTTTGGTGGAGCCGAGTGCCGGGTTGAGGGGTGCGAGCGAACCGCCCGTGGACGCGGCCTGTGTGAAGGACATCGGCAACGGTGGCATGAAGAGGGGCGTCCGTCGCTGGAGCGGTTCGCCGTGTCGACCGATCCGCGGTGGCGGCGGCGACAACCCAACCAGCGCTGCCGGGTGCCCGGTTGCGGTTACGGCTCTGCCCGTGGCGGCATGTGCGGGCTGCACGCGCAACGATGGGAACGAGCCGGGCGCCCCAGCCTGGCGGGATGGCTGGCCGAACCACAGCCGTTCAAGCAGCCAGCGCCGGGCGCGACCTGCCGCATCCCGCATTGCGAGCTCTGGCCGCAGGGCACGTCTGCGTTCTGCCAAACCCACACCAATACCTGGAAGGGTCAACGGCAGACCCGACATTGACGAGTTCGCCGACCGCTTCGCCGCCGAAACCCCGCTGGCCAGCGAGCAGATCCGGCTCGACCGGCTGACCGGTCAGCTGAAGCTGGAACTGCAGTACGTGCTGCAACGCCGTCACGACGATCGGCAGGGCAAGCTGACCCCGGACGTGGTCATGCGCGTCGTGAAGGCACTGGCCGCAATAGGCGTGGGCTCCCTGCTCAACCACGACGAGGACATCTGGCACGACTGGGCTCGGTCGACGATCAATGACACTCGCTCCCGTGGGTTCCTCAGCTACGCATCCCGGGTGATCGCCGACCTGGCCGAAGCCGGCGGCTGGGACGCCGAATACCCGCGCGATGTCTGGCGCATGCGCCGGCTCGGCTACGACGGAGACCGCACGCTGCGGTTCGGCGGTATTCCGCAGCCGTGGCTGCGGGATCTGGCCAAGCGGTGGGCCCGGTGGCGGCTGTCGACCGGATTGGGCCTGGAAGCCGGCGGCGGCAGGCCGGTCGTTGTGCTCACCCGCTTCGCCGGGTTCCTCGCCGACATCGGCGTCGAGAGCATCGACCGGATCGACCGGCCGGTGCTGGAGCGCTATCTGGCCAACCTGCGCGGCGACTCCATCGGTGCCCAACGTCGCGGGACCCATATCGGGCTGCTCAACCGGTTCTTCGCCGCCGTTCGCCAACACCGTTGGGACACAGACCTTCCCGCAGACGCGATGTTCTTCGCCGAGGACTACCCGAAACGCGACGAACGGTTGCCTCGGGCACTGGCCGAACAGGTCATGGCTCAGCTCGAGGATCCCGACAACCTCGCCCGATTCACCGATCCTGCCCACCGGTTGATCACGATCATCTTGATGCGTTGCGGGCTACGGATCACCGATGCGCTACGGCTGCGCCGCGATTGTGTGGTCGCCGACGCCGAAGGTGCTCCGTATCTGCGCTACCTCAACCACAAGATGAAACGCGACGCGTTGGTGCCCATCGACGTGCAGTTGCGCGAGCTCACCGCCGAACATCGCAACCGCACCGCCCAGCGTTGGCCGGCAGGCACGCCGGTGTTGTTCCCACGGCCGACGAAGAACATTGACGGCACCCACCCGATCGCCAGCCCCACCTACCGGATGGCGCTGTTGCGCTGGCTGTCCGTCTGCGACATCCGTGACGAGCACGGCCAGCCGGTGCACCTAACCCCGCACCAGTGGCGCCACACCCTGGTTATCTGTACTGGCAAGGAGCGCGTGAGCTACGTGAGTTCGGCGGCGTGACACGCCGGTGCCTTACGAATATCCGGTACTTTCAGGCACGGCCGTTACGTTTGTCACGTGAACTCGTTCCACGCTGAACGAGCGGTTTCACCCCTCGATGGATCCGAGGTGTGGGTGGTGCTTGACACCGGGTTGGTGATGCACCGGGAGGCCAGCGATTTCCTGCGGGCGCTGCATGGGGCCGGGCGTTCGATCCACACGATCCGTGCCTATGCCGGGCGGGTGGCGAGTTTCCTGGGATGGTGCGCCGATCAGGGGGTGGAGTGGTCGTCCATCAGTCTGCCGGGATTGGCCCGTTTCAAGCATTTCATCGAAGCCACCCCGCGCCGGGATGGGCGGTTGCGTTCGGGCGCAACGGTAAACGCGATCCTGACCGCGGTGTGTGAGTTCTTACGGTTCTGCGCCAGGACCGGCGTGATCGAGCAGGCCGTCGCCAACCGGTTGTCTGAACCCCGCTGGCTGCGGTTCACCCCGCCGGGTTTTGATGCTGGAGAATCCGGCCAGTTCCGGATGGTGCGGACCCGCACGCTCAAGGCGAGGGCGGAAGCGGTATTTCCCGAGGCGTTTACACCCGAGCAAGCCGAACGGGTCGCGGCGTGTTGTCGCCGGCCGCGGGAACGATTCATGGTGGCGCTGCTGCGGGATGGGGGCTTGCGGATCGGAGAAGCTCTCGGATTGCGCCGATCCGATCTGCACCTGCTTCCCGATTCGCGGCGGGTGGGTTGCACGGTGCTGGGAGCTCACGTTCACGTGCGGCACCGGGCCAATCCCAATGGCGCGCTGGCGAAGTCGCGGTTTCCGCACCGTGCCGACGAGCCAGGCGGTGCTGTCGACGTACGCGGACTACCAATTCGAACGTACGGAGATCCTCGGCGGCGACGACTGCGACATGGTGTTTGTCAACCTCTACCATGAGCCGCTGGGCGTGCCGATGACCTATCGTGCGGCGAAACGGTTCTTCGAACGGCTGGCCACCGACTGCGGGTTTGCGGTGCGCCCTCATATGTTTCGGCACACGGCGGCCACGAACTGGGTGCGTGCCGGGGTTGATCTTGATGTCGTGCAGCGGCTGTTGGGGCATGCCGCGCTTGCCTCGACCGCTGTTTACCTGCACGCACGAGATGAGGATAAGCGCCGAGCCGTGGAGGCTGTCGCCGCCGGGGAGCGCTTTCGATGACCGCGCCGGTGTCGCGTCTGCTGGTCGGCACCGACGCCGACCAGGGGTTGGTGAGTGACGACGCCAGCTGGCTGCAATGGCTGTCTGCCCATACCGATGCCGCGTGGCGGCCGGGCGAATGGGACGGGTCGCTGTGGCTGTTCACCGGCGATTTGGACAGCGATCGGACCGCTGCGTGGCGGTGTCGTACTCCGGGCTGTCCTACGGCGGCACGGGGCTTTAACGGCCGCTGTTCGAGTTGTCGGCGGGCGCGGGCGGCGGCCGGTGTCTGCGAGGAGGAGTTCGACCGCGCGCCTCGGCGTCGCCCGACCCGCCCGGTTGCCCGAGGTGACTGCGTGGTGCCCGACTGCGGGGGCGAGTTGCATTGCCGTGGCCTGTGTTTCCGGCATGAGCGGGCCTGGCGTAAGGCCGGTGGCGGGCCGCTGGAGGAGTTCATCGCGCAGGCTCGGCCGCTGATCGGTACCGAGCCGTGCCTGGTCGCAGGTTGCGGCCGCGAACGGGTAACCCGGCGAGGCCTGTGCCGGTTCCACGGCAATCGGCTGGCGCGGCAACGCAACCCTGCGTCGATGTCGCAAGAAGAGCTGGCCGCGTGGGTCGCCGACGAGAAGCCCGGATCTCGGCCCACCAGTTTTCGTTGGCTGGCCTGCCCGAGCTGGTGCGCTTCGAGTTGCTTTATGCGCTGCAACGCCGCGATGAGGCGCCGCCTCCGTTGGACCCGCTGCAGGTGCGGATCCTCATCAGCCGCCTGGTGGGGGCCAGCTCGCTCCGTCACGCCGATCCCGAAGCGGTGTGTGAAAGCGGTGGCGTGCAATACAACTCGGCCATCAAGGGCTTGTTCCGCGACCTGCGCCGTCATCTGGAACGAGCCTGGACCCAGTACACCGGCACCGACCCTTATGCCGGCAACGTGTGGCGCGTCGAGCTGCTGGACCTGCAGTCCAACGGCTCGCGCCGCTGGCCCGCCACCAAGGGGACCATCGACTTCGGTCCTATCGAGCTGGGTTGGCTACGCGAGGTGCTCAAGGACTGGGCCCGCAACACCCGGCCCTACCTGCAAGGGCTGCGCCAAGCGCTGCGGGCCTGCCACGTCGCCTCCCAAACGCTGGTGGCCTGCGGCCGCGCCGACCCGGCCAGCCTGGGCGCGGGCGACTTCGTCCTGGTCGAGCAGGCCATCGTCGAGCAACGCCGCACCGATGGCTCTCCCACTCCGCCTCACACCGCACCCAGCTGCTGCGGCTGTTCTGTGCGGTGATCGAGCATGGCCGCGCCAACGCGCTGATGACCGACGTGCCCGACCCGTTCCGACCACCCCAGCGCCGTCACCGGGTGATCGAGGACGCCAACGAGGAACAGCTGGGAAAAGCACTGCCCGACATGGTGATTCGCCAGCTCGACCAGCACCTTGACCTGTTGGGTCCGGCGGGCCGACACGGCTCGATGAGCGCCCCGGACCTGCAGGCAATGCACCGGACCATCTACCAGATCCTGCGTGACACCGGCCGCCGCCCTGGTGAGATCGTCAGCCTCAAGATCGGCTGCCTCGAGGTCATCGACGGCCAACACAACCTGATCTATGACAACCACAAGGCCGCCCGACTGCGTCGACGCCTGCCCATCACAACCGACACCGCCGAGATCATCGCGGCCTGGCAGCGTCACCGCACGCAGCTGCCCACCGCGCCGGCGACCCGCCAGTGGCTATTCCCATCCCCGCTGTTGCGCTCCCGGCAGGCCCGCGGTCACTTGACCGCCTCCTGCGTCGGGGTGGCGTTTCGGACTTGGACGCGCTCGATTCCCAAGATTGACGGCGAACTGCTGGGCCCCGACGGCACACCGCTGCCGTTCGATCGCTCGCTGATCACCCCATATGTGCTGCGGCACAGCTACGCTCAGCGACACGCCGACGCCGGGGTGCCCGTCGATGTGCTTAAAGAGTTACTTGATCATCGCTCAATTGAAACGACGCTTGGCTACTACTCGGTCACCCACAAACGTAAGCAGCAGGCTATCCGTGCCGTCGGATCCTTGGCCATAGACGCCTCGGGCAACCCGTCCTCGTTTGCCGACCCGCTGGCCTACGAACGGGCATCGGTGTCGGTCCCGTTCGGTAACTGCACCGAACCGTCCAACGTCAAGGCCGGTGGCGGTGCCTGCCCGATCCGATTCCAGTGCGCGGGCTGCGGCTTTTATCGCCCGGACCCGTCCTATCTTCCCGCCCTCGAAGAGCACATCCACTCGCTTCAGGCGGACCGGGAGACCGCCCGGGCAATGGCGGCCGCTGACTACGTGGTCGCCAACATGAGCACCGAGATCGACGCGTTCACCCGCGTGGTCGACACCATGCGGCGCCGCCTCGCCGAACTCGGCCCCGAGCAGCGAGCCGAGGTGGAGGAGTCCAGCCGGATCCTGCGCCGCGCCCGGGCCGCCCGCCGCCTCCCGCTCATCGTCACCTCGGCCAAGGACGCCGGATGAGCGCCACCGCGGCCAACCAGATCCGGTCCGCAGCGCTGAAAGCGGCCCGCGCCAAAGACAGCCAGCGCAAGCGTCAGCGCACGCTAGCTGCGCTGCAAACCCTTGAAACCACCGGCGCGCCGATCACTTTCACCGCGGTGGCCAAGGCCGCCGGGGTGTCCACCTGGCTGGTCTACGCCGACGGAATCCGCGAACACATCGACGCGGCTCGACACCGCCAGAGCAACCATCACCGCCGGACCGACACGCCGGCAGCCTCCAGCACGCACCCGGCGACGCCGGACAGCCTGCGCGCCGACCTGGCCATCGCCCGGGAGCAGATCAAGACGCTACGCACCGAACGGGACAAACTCCAGCAGCGCCTGCGCCTGCAACTCGGTGCCGAACTCGAAGCACCCGACCGGGCTCACCTAACCGCGCGGGTCGTCGACCTCGAGACCATCAACCGTCAACTCGTCGCCGAACGCGACGCGCGCGCCATCGAGGCACAAACCGCCAAAGGTCGGGTCACCGAACTCGAAGACGAGCTATCCGCCGCACGCGAAAGCCTGCGCCGGGTCATCAAAGCCCAAAACCGCGCACCATGACGCACACCTTTGCAGCGACTCCCGCACGCAGCCGCACACTCCCACGTGCCTCACGTGCCCCACACTTGAAAACACCTCTGACCAGCACATTTTCAGAAAAAATACAGATAACCTACGGCACCCGGCTGATCAACCGCGACGTCCCACAAGAGGTCGTGCGACGCATCCTGGACCACGACTCCGCGCAGATGACCGGGCATTACGCCCGCCTGCACGACACCACCGTGCGCCGCCAGTGGGAGGCGGCCCGCAAGGTCGACATCCACCGCACCACAATCATTTTCGACCCGTCCGGTCCGATCGCCGCGGCCGCCTGGGCCAAACAGCGCCTCGGCCGAGCCACCCAGGCCCTACCCAACGGCTACTGCGGACTGCCGGTGCAGCAGAGCTGCCCGCACGCCAACGCCTGTCTGACCTGTCCGATGTTCCTCACCACCGCCGAGTTCCTGCCCCAGCACCACCAGCAGCGGCAACAGAGCCTGCAGCTGATCACCGCCGCCCAAGCCCGCGGACAACAACGTCTGGCCGAGATGAACCACCAAATCCTGCACAACCTGGACAACATCATCACCGCCCTCAACGATCCACAACCAGGGAAGGCCAAACATGCCGGCTGACAACAGCATCCACCTCATCCACGCCGCCCAGCAGCGGCACGAACACACCCGCGCCAAGGCCATCGCTGCGATGCACGAACTCGACCGGACCGGCGCCCTGCTCACCTTCGAATCCGTCGCCCGCCACGCCGGTGTCTCCCGCTCGTGGATCTACACCCAAACCGACCTCAAAGACGAGATCCGCCGGCTCCGCACCCAACACCGACCCGAGCCAAGCACACCGTTACCCGCCCGACAACGCGCCAGCGACGACTCCCCGCGGCAGCGCCTCGAAATCGCCAACCGCCGCAACCGCGAACTCGCCGACGAGAACCGGCGGCTACGCCGCCAACTGGCGTGCGCCCTTGGCCAACTCCGCGACGACACCGGCCGACATCATGAACCGACGCATCGCGATTCGGTAACAATCGGGCCGTGCTAACCGCCAAGCGATATCCATCTCCAACCGCGTCATGGACACCCTCCACGACACAAACCTGCAGGTCACAACAGCTACCGCGGCCAGAACTCCAGATAACAATCGAGTCACTCAACGCCCGCTACCGACGGGCGATCAAGGCTCGCGGCCATTTCCCCTCGGAGGCCGCGGCGCTGAAGTGCCTGTATATGGTGACTCGCTCCCTCGATCCCAAGGGCACCGGCCAGCAACGCTGGGCGGTCCGCTGGAAGCCCGCTTTGAACGCGTTCGCAGTAACATTCGCCAACAGAATGCCCGACCTCAACCGAGGATAGGGAAACGCCACTTACACCGAATTCCGGATGGACCCGTCGGCGAAGTGCGCGGCCACTTCGCCGGTCGTTAATCCTTTAGCGGTCAACGACAACACGATCTCGTCGATGCCGGTCAGCCGACGTTGGCGCTTCTTGACGATCTGCGGATCGAACGAGCTGTTGGTATCGCGCGGCACCTCGATCTCGACCGGTCCGATCTCGGTGAACACCGTCTTGGCCCGGGTGCCGTTGCGGGCGTTGCCGCTGCCACGTCCGACCGGGTCGTGCTTGTCATAGCCGAGGTGCTCGGCCATCTCTGCGTCCAGCGCGGTCTCCAATACATTCTTGGTGATCTGGTTGAGTAGCCCGTTCGGGCCGACCAGCTCCACGCCCTGCTCCTTGGCCTGGGCCAATAGTTGTTCAGCGAGCTGCTTTTGATCCACCTCGGTAGCCATGGGCTCGAGTGTTTCGGACATCATCAGTCCTTCCCGCCAAGCTCACGCTCGGCGTGTCAGACCAAGGTCAGATCCACCGCTGTTCAGACAGTCCCCATCCTCAGTTTCGATTGCAGGGACCAGATCTTGTTGAGCAACAGTGCCTTTGTGTCGTAACGGTGGTAGCCGACCACGGTGCGCACGATCGCCCAGTTCTTCTGCTCGACGTGGCAGCCGTCGTTTTTGTTTCCGGGCCGCGAGCGGGTGAAGGTGATCTGGCGCCGCTCGCACCAAGCCAGCAGGTGGTGGTTGATGAACTCGCTGCCGTTATCGAAAGCCCAGGATCGGGAAGGGCATGGTGGTGGCGATCGAGGTGCCTCACCAAAAAGTGAGCGCGAAGCGTGGGCTGGTGCCTCACGCATGGTGAGCGCGTGGGGGCTTGCACTACTTCGCCTTGGCCAATCGGTCGATTGACGGTTGCAATGCTTCCAGGTCGATGTGGCGGGCGGCGGCAAGGGCGTCGGTCTTGGTCTTGGCCAGGTCCAGTAGCTGCATTTGGATGGTGTTGATCTGCCGGGTCAAATCGGCCGGGTTGATGCCCTCGATTCGGGCGGACACATGCGAAAGCTGTTGCGCATCAAGTATTCCCGATTCCTGCAGACGTTGCCACGGCGTGGCCGGCGTGTCGTAGATGCGCGTGCGGCGACTGGCCGCGGTGGTGCTGTAGCCGATGGGCTTTTTCGTCGGGGTGAAGAAGTTGCACCGCAGCGACACCAGCTTCCACAGCCGGTTGAGCAGCTCCAGCTCCTCGGAGGTGTCGTAGCGCCAGTAGAACGCGTGTTTGCGCACCACGTGGTTGTTTTTTGACTCCACGTGCGCTTGGTCGTTCTTCTGGTACGGCCGCGAGTGGGTCTGGGCGATGTCGCGGGTCTGCAGCCAGGCGGCGACCTCGTGATTGATGAACTCACCGCCGCAGTCCAAAGCGAAAATCACCAGATCGAACGGGAACCGCTGTTGCAGCTCGTCGATGCCGGCCGTGATCCACTTCGAGGCGTTGTTGCGGATCGAGAAGTTCTCGGTCCAGCCGATCACCAGGTCGGTCATCGTCAGCGTGCGGGCGAACTCGCCGATCAATGTCGGGCCGCAGTGCGCCACGGTATCGGCCTCGATCACCCTCGGGGCCTCAGGTGCCTCATCGGCGCAGGTACGGATGGCGATCGAGTTACGCAGCAGCGGCGACGGTTTGGTCGTCGAGATGCCCTTGATGCGCATCCTGTCCCAGGGCCGGTTTCAGGTAGCGGTCCAGGGTGGCCGCGCTCATCGCCTTCAGCTCCGCTGATGCCGCCTCGGTGGCGAACGGCCTGTCAAGATCACCGGATTCAGCCAGCAGCGGCAGCCACAGACCCACCATGACCACCAGGTACTTGCCGCACGGCATGCCCATCAAGGCCCACACATACTCCAGCAGTGCCCTGGCGTCGTCGCTGAAGCCCCGCGGCCGCAACGTACGCCTGTCAACCTGCTCGGCCGGGTCCGGCAGCCTCGGGCCGGTCAGCATCCGCCGAGCCGTCGAGCGGCCCATCCCCGTGGTGGACACCACCCGATCCAAAATCTTGCTCTTGTCCGCCTTCAACGCCTTGCGGTACTGACCTCGCAGTTTGTTCGCTACCTGCCGCCTCGCAGCCATGTCGATCTTGCCTTCCACATCGGGCAGGCCTTCCGGGCCACGCGCTCAAAATAGGTGAGGCACCACCGCCGGCCACGCGCTCAAACTCAGTGAGGCACGCCGGACTATTGACAATTGGTCGATCTTTGTAAAAGATTGGTAATACCGTCTGTCCGGGGTATTCGGGAGCAGCCAGTTGCCCGGTCGACGGCCGTCAGTATCCGGGAATGACGGGCAAGGGATCCACGCTATGCAAAGCACTATGCAAGACGTTCCGCTTTCTGTGACATCGATCGTCAAGCATGCCAACTCCATTCACGCCGACCGCCGCGTCGTCACACCGACCGAGTCGGGCTACCGGGCCGCGACCTACGGCGAGGTCGGCCGGCGGGTCGGTCAGTTAGCTAATGCGCTGCATGACCTTGGCGTCACCGGCGATCAGCGTGTGGCTACCTTCCAGTGGAGCAACCAGGAACACTTGGAGGCCTATTGTGCGGTGCCGTCGATGGGCGCGGTGTTGCACACGCTCAATATTCGTCTTACCGCCGAGCAGCTTGGCTACATCGCCAACCACGCCGACGACAACATCGTCATCGTCGACATGTCGTTAGCGCCGCTACTTGCGCGTTCTTTGCCGGCCATATCGTCGGTGCACACGGTGATTGCGGTCGGTGAGGGCGATCCCGAGCCGCTACGGGCGGCCGGCAAGGCCGTCGTTTCGTACGAAGACCTGATCTCGACACATCCCACCGAGTTCGACTGGCCTGAACTCGATGAGACGTCGGCCTCGGCGATGTGCTACACCAGCGGCACCACCGGAAACCCCAAGGGCGTGGTCTACAGCCACCGATCCACCTACCTGCATTCACTGGCCGTCTGCACTGGCAACGGGTTGGGCATCGCTGAAGCCGACCGCATCTTGGCTATCGTGCCGATGTTTCAAGCCAATGCGTGGGGCCTTATCTATGCCGCGCTGATGGCGGGGGCCGAACTGGTACTCCCGCACCGATGGCTACAACCTGGAGCGCTGGTGGCCATCATCGAGGACACCCGCCCGACCGTGGCCGGTGCGGTGCCCACAATCTGGAATGACGTCCGGCACTTCCTGGGCTGCGAGCCCGGTCATGACATCTCGTCGCTGCGTCTGGTCGCGTGCGGCGGATCGGCGGTACCGGTGTCACTGATGCGCGGCTTCGAACGCGACCACGGCGTACCGATCGTGCAGGCGTGGGGAATGACCGAAACCTCGCCGCTGGCCACGGTGGCCAAACCGCCGACTGGGCTCGACGAAGACCAACAGTGGGCGCTGCGTGCCACCCAGGGCCGCCCGATATGCGGCGTGGAAATCCGGCTGCGCAACGACCAGGATCGCACCCTGCCGTGCAACGGAGAAGCGGTCGGCGAGATCCAAGCCCGCGGGCCGTGGGTAACTGGCTCTTATTTTCGCGACGACGACGCCGACAAGTTCGACCAGGGGTGGCTGCGCACTGGCGATGTCGGCCACGTCGACGAGCATGGCTTCTTGACGCTGACCGACCGTGCCAAAGACGTCATCAAGTCCGGCGGGGAGTGGATTTCGTCGGTCGAATTGGAGAATTTGCTGATCGCCCATTCCGGGGTACATGAAGCCGCGGTCATCGGTGTGCCCGACGAGAAGTGGCAGGAGCGTCCACTCGCTCTAGTGGTGGTCAAACCCGGCGCCGATATCACGCCAGATGAGCTACGTGCCTTCTTAGACGGCAAAGTCGCTACGTGGTGGATCCCGGAGCGCTGGGCCTTCGTCCCCGAAATCCCGCGAACCAGCGTCGGTAAATACGACAAGAAAGTGCTTCGGGCATGTTACACCGCCGGTGACTACAACATCGTGGAATTCGTCTAGCGACCAAGGTTCGCTAGACCCGGCAATGCAGCCGAATAATTAAGGAGGTTACATGGCAACCACACGTTACCATTCGCTGGGTGCCGGCGGGCTGAACTGGGAAAGCGTGCCACTCAGGCTGTTCGCTGGCGGCATCGCCAAACTCTGGGACCCCGCCAATATCGACTTCTCCCGCGACAGCGCCGATTGGGAGGCGCTTTCCGACCGCGAACGCGTGTACGTCACCCGATTGTGCGCGGGCTTCATTGCCGGAGAGGAAGCAGTCACCCAGGACATCCAGCCGTTCATGGCCGCAATGCGGGCCGAAGGCCGGCTCGGCGACGAGATGTACTTGACGCAGTTTGCGTTCGAGGAAGCCAAACACACCCAGGCGTTCCGCTTGTGGCTCGATGCCGTCGGGGTGCGCGACGACTTACATAGTTTCCTCGATCAAACTCCGGCATACCGGCAGTTGTTCGACGAGGAACTTCACGAATCGCTCAACACGCTCTATGTGGATCCCTCGCCGGCTGCCCAGGTTCGCGCTTCGGTGACGTACAACCACATCATCGAGGGCATGTTGGCGCTGACCGGCTACTACGCCTGGCACAAGATCTGCGTGGAGCACGGCATTCTTCCCGGCATGCAGCAGCTGATTCGGCACATCGGCGACGACGAGCGACGCCACATGGCATGGGGCACTTTCACCTGCCGGCGCCACGTCGCTGCCGACGACACCAATTGGACGGTGTTCGAAACGCGCATGAACGAACTCATTCCGCTGGGGCAGCGCCTGATCGACGAGGGTTCTGCACTGTATGGCGACGACATACCCTTCAATCTGTCAATCGACGAGATGAGGACCTATGCCACCGACAAGGGGATGCGCCGGTTCAGCACGATCAGCAGCGCCCGCGGGCGACCGCCCGAGGAAATCGACCTCGACTACTCGCCACTGCAGCTGGAGGACACCTTCGCGGACGAGGACGCGAGGGTGCTGGCCGGTTCGGCCTGACTTCGACGAGATCGGCGCCAGTGCGTAAAAACGCGGAATTTTTGCGCTGGAGTCGATTCGGCACTGCGAGTACCAACACTGCTCCAGCTTAGTTGCCGTCGCCGGTGCCACTATCTCGGCACGCTTCAAAGATCCGCGATGGCGCAACGCTCCAAGCGGCGGCGAGGCCAGTCATTGACCGCACGACCCGGAGGAGACGACACACGATGCGTCGACCACTTGAGGACGGCTACTTCACGATGCCCAACGGCGATGAGCAGCCGCGGTTGATCGGTTCCTATAGCCCTGCTGCCGACAAGTACTTCTTCCCCCGCCGCCGCCGCTGTCCGTTGACGGGCGGCCCGGTCGAGGATGTCCTGCTGTCACCAACCGGCGAACTGTACGCCTGGACCTACGTCGAGTCGGCGTGGATGGGCAAGTCCCGGTTCGGCTCCACAGGCGACGGGCACGGTGTCGGCCAAGTTGACCTACCGGAGGGCGTGCGCGTGCAATCCATCCTGCGTGGCGAGATGGGCGACTGGGAGATCGGCATGCCCATGCAGCTTGAGGTCTACCCCCTCATGACCGATGCCGATGGCACTGAGCTGTGCTCGTTCCGCTTTTGCCCTACTCGACGGGGGGCATCTCGGTGATGGCCCGCGACGTCTATGTGATCGGCGTGGGGATGGCCCCGTTCGGCCAGCCGGACGCCAACGCGGCCGACTTGGGCTTCGGGGCCGGTGTCAACGCGCTCGGTGACGCCGGCATCGGCTTCGATGAAGTCGGCTACCTCTACAACGGCTACATCGGCGCCGGTCTGCTCACGGGTGTCACCCTTGCGAAGGATCTCGGGCTTACCGGCATCCCGATCACCCACGTCGAGAACGCGTCGGCCACCGGATCGTGCGCCTTCCATGAGGCGGTCCAGGTGGTGGCGGGGGGGAGCGTCGATATCGCGATGGCGCTAGGGTTTGACGACCTCAATCGCGCCACTCGAGCTATCGGGGGCAGCAAGCCCGGCATTGGCCAGGTGATCCTCCCGGCGGCGTTTTTCGCCATGTGGGCGACACGTCGCATGCACGAAGTGGGCACGACGGTCGAGACCTTCGCCGCCATCGCGGCAAAGAATTGGAACCATGCGCGGCTGAATCCCTACGCGCAACGTCGGGCCGACCATGAGGTCACCGTCGAAGAGATCCTCGCCTCGCGCATGATTTCCTACCCGCACACTTCGAAGATGGCCTGCGCCGCTGGCTCTGGGGCTGCGGCCGCGATCGTCGCGAGCCGCGAGGCGGCAGAGCGCGTGGCCGGTTCACGCCCGCTGGTGAAGGTGGTCGCCAGCCAGCAGCAGTCCGAGCAGTTCGTTGACGGCCACATTTTCATGGGTGCGGTCGTCGGTCCGGGCGAGCTCACCGCGGCCACGGCAAAGGCCGCCTACGACGAGGCCGGTGTCGGGCCGGCCGACCTCGACCTCGCCCACGTGCACGACGCATTCCCCATCGAGGAACTGATGTATTACGAGCTGCTCGGGGTGTGCGCGGCTGGGGAGGGGGACAAGCTCGTCTCCGAGGGCGCGACCAGCCTGGGTGGTCGTATCCCGTTCTCGACCGACGGCGGGCTGATCGGGCGCGGTCATCCCGGTGGGCCGACCGGCCTGGCCCAGATCTGGGATGTGACACGGCAGCTGCGGGGCGAGGCGGGCCCGCTGCAGGTCGAAGGCGCTCGAACCGGGCTTGCTCACATGATGGGCGCGGGCTCGGTCTGTGTCATCCACATCCTGCAGGCCGGGCGGTGACGTCATTCAACACATCCGATAAGAGAGAAATCGCCCTGCGGGGCGACAGCATGGAAGGGAAATCGCGTGGCTGAGCTTAGCTTCGACGGGAGGGTCGCCATCGTGACCGGGGCGGGAAACGGTCTCGGCAAGGAGCATGCGATGCTGCTTGCATCACGCGGCGCGCGCGTGTTGGTGAACGATCTCGGCGGCAGCGTCGCCGGCGTCGGCGCGGACCTGACCGCGGCGGAGGCCGTCGCTCAGGAGATCGAAGCCGCCGGCGGTATCGCGGTCGCCGATGGTCACAGCGTGGCGACCCGAGAAGGTGGGGCGGCCATCGTGCAGGCGGCTCTCGACGCCTTCGGGCGGGTCGACATCGTCGTCAACAACGCGGGCATCCTGCGCGACAAGTCCTTCCACAATCTCACGCCGGAGCTACTCGATCCGGTGATCGATGTCCATCTCTACGGCACCATCTGGGTGACCCAGCCGGCGTTCCTCAGGATGCGCGAGCAGGGCTACGGCCGGATCGTCAACACCTCCTCCGCCGCCGGGATTTTCGGCAACTTCGGTCAGACCAACTACGGGGCCGCGAAGATGGGGGTCATCGGCTTCACACGGGTGCTCGCCCAGGAAGGCGCGAAGTACAACATCAAGGTGAACGCGATCGCGCCGATGGCGCGGACCCGGATGACCGAGGAACTCCTCGGGCCGATCGCCAAGAAGCTGGACCCGGCACTGGTCGCCCCGGTCGTCGCGTATCTCTGCCATGAATCCTGCGATCTCACGTCGAGGATCTTCTCCGTTGGGGGCGGGCGAGTGGCCGAGATCTTCATCAGTGTGACGAAGGGCTTCTCATCGCCGACGCTCGATATCGAAGCGGTCCAGGACAACCTTGAGGCGATCTGCGACCGAGAGGGATACCAGACTCCAACGCAGGCCAACGACGAGATCGGCCTCGTGCTTCAAGCGCTCGGCTGAACACGTACGTACGTTGAGGAGGACCATGCCATGGCCGTGATCGACCTGCTGCGCCAAGCGGTAGAGGACCGACCGGACAAGACCGCCGTCATCGCCGAGGACGGCGCGGCCACTTTCCGCGAGCTCGACGCTGCCAGCAGCCGGGTCGCCCAGCAATTGCACGCCGCTGGGGTGAGCCGCGGTCACAAGGTGGCGATGCTGCTCGCCAACGACCAAGCGATGCATTTCAATGCAGTGTATTTCGGCATCCACAAACTTGGTGCCGTGCCGGTGCCGCTCAATACCCGGTGGGCAGCGCCGGAAAAGCTGTTCGTGCTTGAGCACAGCGACGCCGTGGCGGTGATCACCGGTCTCGCCCACCGGGAGGTTCTGGTTGCGCTTGCCGAAGGCGAATCTGTCGAGATCGGCGGCCGTCCCGGTAGCTTCCAACTTGAGCACTTCTTCGTGACCGGCAGCGAGGCGCTGGATGGATTCACCCCCCTGGGCGACGTGGTGGGCGCGGGCTCTGCGGACGTGCCGCTCCTCGAGCCTTCCCTGAGCGCCGACGACCCGGCGGATCTGCTCTATACGTCCGGCACCACCGGGATGCCCAGGGGCGTGCTGGTGCCCGAGGGCAACCTCGCCGACGAGCCCGGCCAGGCGAGCCTCGGGCAGCTTCTCGGCGCGATGTTCGGCGAGAGCCTGCTTCATGCGGTGCCCTTGTTCGGTTTCACGGGCTGCCATGGCCTGATGCTGCTAAGCATTCGTGCCGGGGTCACGCAGATCGTGTTGCCGCGTTTTGATCCCGAGCAGTTGCTCGCGGCGATCGAGCGCTACCGCGCCACGTCGATCATGGGTGTGCCGACAATGCTGAATTTGGCCATGAAGCACCCCACGGTGGGTGATCACGACTACAGCTCGCTGCAGCTCGTGTTTTTCGGGGCGGCGCCGATCCAGCCCGACACCGTGCGCAAAATGCGGCAGGTGTGGCCCGGAGCGAAGATGCTGAACGCTTACAGCCTCACCGAGGCCGGTGCCGGCGCGGCCTGCATCCTCGGTCCCGACCCAGATGACATCCTTGCCCGGCCGGGCTCGGTTGGCAGGCCCGTAGGATGCGAGGTTGTCGTCGTTGATGACTACGATAACCCACTCCCCCCAGGCAAGGTCGGCGAGATCTGCTTTAAGTCGAAGATAGCTCGGCGCAGCTACTACAAGGGGGAGCAGCCCACCGCGGAACTTTGGAGCGGTGGACTGTTGCACACCGGCGACGTGGGTTATGTCGCTGACGATGGCTACGTCTATCTGACCGAGCGCAAAAAAGACATGATCCTGCGCGGCGGCTACAACATCTTCGCCATCGAGGTCGAGCGCGTGCTGCTCGAGATGCCCGAGGTGCTCGAGGCCGCAGTCATCGCGGTGCCGCATTCGGACCTCGGTGAGGATCTCCTAGCGGTGATCGCGCCCAAGCCCGGGTTCAGCGGCGGCGAAGGCGAACTCACCGCGGAGCGGATCAACCAGTTCTGCCGCCAGCACCTCGCCGACTACAAATGCCCGCGCCACATGGTCGTAGTGGACGAGCTACCGAAGAACGCCATGGCCAAGGTCATGAAAAACGAACTCCGACAGCGCTTCCGAGATCACCTGTTCGATCAAGGGGCCGAAAACAAATGAATGCTCCTTGAATATCGGCTTAACAGCGCGACGGCGGCCATTCCGAGCAGTGTCCGGCGCATAGCCACAGAAGAACCGTAAAGCGAGCGGATGGGGACGGCGGAAGATGCCAAGGCCGGTGAGACAGTGCTTACGCGGAATTGATGAGCGCTTCGGTGTGTGGATTGGTCGATCCAGGCGACGGTAAGGCCGTCCCTATTTCTTTTCGCGACAACAACTGTTTGAAGAGAAGATGAGGTGCCATGTCATGGATTTCATGCTCAGTCCAGAACAGGACGATTTCCGCCAGACTATACAGCAGTTCGTTACCGAACTGTCACCGCTGGCCAAGGTTCGCCAGGCGGTAACAACTGCGCCGGGATATGACATCGACCTTTGGTCTCGCATGAGTCGGGAACTGGGGCTGCCGAGTCTGCTCGTACCGGAGGAGTACGGCGGTGCGGCAGCAACGATGATCGAGGCTGCTGTCGCCATCGAGGAGCTTGGACGCGGCATCGTGCCGTGCCCGCTGTTCGCGACCGTCGCGCTCGGTGTCGCGCCGATCTTGATCGCGGCCAGCCAGGAGCAGAAGAGAGAACTGCTTCCAGAGATAGCCGCGGGCGCTCGTACAGTCACGACTGCTATCAATGAACCGGGTTGCGTTGACGGCTTCGGTGCTGTAGCCATGCGAGCGGCGACAAATGGCGACGCCGTCACGCTGTCTGGGACCAAGATTCATGTGATCGACGGCCATAGTGCGGACACCCTGCTGGTGCTCGCTCTGCCGCCCGGTGACTCCGCTGAGCCGGCATTGTACCTCGTTGACGGTAACGCCGTCGGCCTCACCCGTACACGCGTCGAGACCCTGGACATCACCCGACCGCTGGCCACCCTGACCTTCGACGCCGTCTCTGCGGTTCCCTTGGCTGGCGCGCACGGCGTCGCGCCCATACGCCGTGCGTTAGATGTCGCGAAGACGTTACTCGCAGCGGAGATGGTTGGTGGCACCGAGGGCGCTATGACCATGTCCGTCGAATACGCCAAGGTGCGTCACCAGTTCAATCGGCCCATCGGCTCCTTCCAGGCGATCAAGCACCGATGCGCCGAGATGGCAATCGAACTGGACAGTGCTCGTGCAGTCACTCTCTACGCGGCTCATCTGGCAGCGGAGGAGAGCGCTGACCTCGCCAAGGCGGCCCCCATTGCCGTGGCAACCGCCGCGGCCGGATTTGACTTCACCGCATCGTGGAATGTGCAGATTCACGGCGGGATCGGGTTCACCTGGGAGCACGACGCACACCTCTACTACCGGCGGGCGAAAGCCGACCGGGTACTGCTGGGCTCAGTACGCGAGCAATGGCTCGAGGTCGCTGACCGCATCGGGCTCTAAACACCGCCACATACTTCGTCGGCACGAACAGAGAAAGATGACATGTGGATGGGGACCCCCTCAGCTCAGACGCTCGTTGATATAGGCGTTAGAGGAATTTTTCAGGAGCTCGAGGAGGTCCCGATGACGATGGTAGGCGGTTTCGACGTGCGGCGACAGCAGATCACATTCGATTACGTCGATTATGACGGCTTGTTGCGCTGGGGTCAGATCGGTCCGGCGACCCGGAAAGCGTTGCGGAACTGGCTGGCTGAGCACTGCAGCGATGGGGACGGCCAGTTCGCGCTGGAGGGCTGCCCGGGGTGGCGGTATGTGTGCGAGGAGCTGGCCGCTGCTGGGATCTGCGCGCACCTGGGGGATGCGGCCGAGATTGCCGTCTTACCGGAGCCCAAGAAGCGCGCCAAGACCGACCGCGCCGATACTCGGTTGCTGCGTACGCTGTTGTTCGAGGACCGGTTCCCCGAGTCGTGGATCCTACCCGCACACATGCTGGAGATCCGCACGCTGGGCCGGTTGTACTACACGTTGATGGACGAGCGGCGGGCCTGGCAGCAGCGCATCCATGTCCAGCTGTTCCATCAGGGCTGTCCACCGATTCGGGCGCTGTTATCCGGCGCAGGCCGCGCGGCGCTGGACAGCGTCGACTTGTCGGCGGCGGGCCGGCGGTGCGTTGACACTGCGCTACGGCGCATCGATCAGCTAAGCACCGAGATCGACCCGCTGCCAAGCCAATTAGTCAACTTCGCCCGACGCCAAGCCGGGTGTCAGGCAATGCAGCGCCATTACGGCATCGGTTGGTTGTGCGCGGCGATCATCTGGTCCGAGGTCGGTGATGTCCGCCGATTCAGCAGTTCCCATCGGCTGGTGCGGTTTGCTGGGCTGGATGTCACCGTGTACTCCTCTGATACCAAACGCTCACCAGGGCACCTGTCGCGAGAGGGCTCACCCGAGCTGCGCTGGGCGGCGTTTGAGGCAGCCGAGTGCGCGAGCCGGCGCCGTTCCCTTGATTACGGTTACTACCACAAGCTGGCAGCCAAGCGCGACGGCCACAACGGCAAGAATCCCCACCCTGGCGGTGGAACGCAAAATTCTGCGCCGATGCTATCACCCGCTGCGTGCGTTCGAAGATGGCGCCCTGGCGCTGCCAGTCCCCGAACGCCAGGAGGTGGCCTCTTAAATGATGCGTTGCGCGCCTGCCATGCCCATTAATCACCTGATGCTAATCACCTGATGCCTGCGGCCAGCGCCCGTGTGGTTCCTGTCGCCACTCCGCTGTTGGGTGGACTTCCCGGAAAGATTGAGCGGCCGCGCCTTCGTTGCCCGCACGTCGGGCACCCCATCGATCATCAAGTTGCCGGATATCGTCCGTGGACTCAGATAAGGCTGGGCGCCGGCACACGCGACGCGCGTCTTTCGCCCCACATTTATGCACCGGAGGGCAGCAGATGACTTGAACCACACCGTCTTTTCCTGTTCCCCGGCGGCCAAGTATGCGGCGGATCCTCGTCGGTCTCAAGGTCGTTCGTCCTCGCTACGCTGCGGGCGCTCCGCCTTGACCCCGACCGCGGTCCACCGCCTTCAAGCGGTCGAAAACGAAGCAAAACACGCAAAAAATAACCCAATGGATCCACCTTTACGCGGGTCCTCAACACAGATAAGGGACGACGATTCGATATGGACCTGTCTTATCCCCCGTCAGCTGAGGCGTTCAGGTCACGAGTGCGCGACTTCATCACCGCGAACGTCCCTGCCGACTTCGCTGGAATCGGGGCGTTGGATCAAACCCGGCGGAAGGAGTTCATCCGAGAGTGGCGGAAGACGCTCGCGGACAACGGCCTACTCGCCGTGTTGTGGCCAAAGCGATATGGCGGAGCGGGACTGACCCCACTCCACCAAGTCGTGCTGGCCGAGGAGTTTGCTCGCGCCGGGGTACCCGCCGGAACTGAGAACGACATGTTCGGGATTCAGCTGCTTGGCAACACGCTTGTCGTCTGCGGCACCGAGGACCAGAAGAATTGGTTCTTGCCGCGAATTCTGTCCGGTGATGATCGGTGGTGCCAGGGGTTTTCCGAACCCGACGCGGGATCGGATCTGGCCAGCCTGCGGACGAGAGCGGTTCTTGATGGCGACGAATGGGTCATCAACGGGTCCAAGATCTGGACTTCAGTGGGACACCTCGCCAACTGGATCTTCGCACTGTGCCGCACCGACATGGATGCTCCCAAGCACCGGGGGATCTCATTTCTGCTCGTGCCGATGGATCAGCCCGGCGTGGAGGTTCGACCCATCAAGAATATAGTGGGCCAGTCGATGTTCAACGAGGTGTTCTTCACCGACGCCCGAACCGCTGCAGACAACGTTGTCGGGGAAGTGAACGCAGGATGGTCGGTGGCCATGACGCTGCTGGGTTTCGAGCGTGGAACAAGTGTCACCACCGACGCGATTCGCTTCCAAGCTGAGATCGACCGGCTCTTCGAGCTGGCGAAAGAACGAGGTAAGACTAACGACCCGCATATCCGTGAGCAGCTCGCTTGGTGCTATGGTCGCGTCGAGATTATGCGGTGTCGTGGGTATCAGGCGTTGACGCGCTTCTTACACGGTGAGTATCCAGGTCCCGAGGCCGCGATGACCAAGATCCTCTGGAGCGAGTTCTTCCAACGCGAGACCGAACTGGCGATGGAGATCCTCGAGACGGACGTGTTGACGCTGTCGGGCACGGGAACGAACGGCGCCTTGGCGACTGCGGATGTCGGAACACCGAATTCGTCGCTCGCGTGGGTTGAGTCGGCATTGGCGGCGCGAGCCGCCACGATTTATGCGGGCAGTTCACAGGTGCAGCGCAATATCATCGGCGAGAAACTGCTCGGCCTGCCCAAGGAACCGCGCCTCTAGGATCCGAACAATGCCGGAGCCCGTAGACACCAGTAGTGCCGCTTCCGGTAGATGGGCGGCCATCTCGAATGCGGAATACCTGCGCAAGTGGCTGGGCCTTGGTATCGCGATCGGCACTCGGCGACGCCTGAAAACTGACCCCGTGTCGACGCAGATTTTGACCCCTTCGACCGATTCTCGGCTTGGGCCGAGAGGAGAAAGGAGTTGTTGTCAGTGGACGATTGGCTGAGATCCGCAGACCGCCGCTGTTGAAGATGTTGCCGAAAAGCGGTTCTCCGCGCAGCGGTCACCGTGCCGGTGATGGGTGCGACCAACCGATAATCCATTTTGATGATCATCACCGGCTCGTCGTGACGAAGTATCTTGCGGGAACAGCGGATGACACCGGACCGGATCCGCAGCGTCTTAGGACGATGCGGGCTTGCTCTTTGAGCAGCAAGGCCTCTGTCAATGGCCATTTAGAAGTGTCGCTTGCCAGGGTGATGGGGCCACCTGATTGCCAGGGGGATGGGACCACCGTGGCGCGTTATTGAGGAAGCTCGTCGTCGTGGTCTGGGTCAAGCTGGCTGGGTCGGGTGCGTTGACGGTAGGACGGTCCTTCGATGACGAGGGTGTGGGCGGTGGCCGTGAGTCGGTCGATCGCTGATTGGGCCAGCAGGGTGTCGGCGGTCATGGTCAACCATTCGGAGGGTTCTCGGTTGGAGGTCACGATGGTCGTTTTGGCGCGGTGGCGTTCGACGATGATTTCGTAGAAGTCGCTGGTCTCTGTGGCGCCGAGGGGTCTGAGCGCAAAGTCGTCGATAATGAGGACGTCGATGGTGGTGAGTCGGCGGATCTCGGCGTCGACGGTGTTGTCCAGGCGGGCGGCGCGCAGCCGGGTGAACAGCTTGTCGGATCGGGCGAACAGTACGGAGTTGCGTCGGCGAATTACCATGTGTCCCAATGCTGTTGCCAGATACGTCTTGCCTACTCCGACCTCGCCGGTGATCACGCCGATGCGGCGTTCGGCGATGCACCAGCCGATGCGGGCGAGGGCTTCGTTGTGGGCGCTGTGGCGGTGCAGCATGCCGGGGGCCAGGTCGCGGCCGAACGGCGTGCGCGAGAAACCGTAGTAGGAGATCAGGTTGTCCATCATCGGGGTTGGGCCTCTTCGCCGGTGAGTAGGTCGAGCTGGCCGGGGATCTGGTCGGCCCCAGTCAGGGCGGCGTAGTTGACGCCGCGGGCCAGTTCGGTCTGATGCGCGGTCTCGATCAGCCGCGCGTAGTCGACACCAGTGGGTTTCGGTGGTATCGACGGGGTTTCGGGTTTGGCCTTGGGGTGCGAGTGCCGCCCGATGTGGTGCGGGATCGCTAGCCCCATCGGCACGCCGGCCAGACGCACCTCGATGCGGGTCAAATCGAACGGGTCGAATACCAGCTCCACCTTGCGCCCAACCAGTGCGGGGTCGACCTCGTAGCTGTTGCCGTGCAACGAGACGGTCGCCGTCTTGGTGACGCGGCGGTGCTCCTCCCACAAAAACGCCTCGGTGAGCGCCTCCGGGGCGGGCAGGCCGACCGGGCCAGACGCGCACCAGCGGGCCAGCGGGGTCTGCCCGGTTTCGGAATGGACGGTGCGGTGGTAGACAGTTTCGACCCAGGCCGCAAAGAGCCGGTTCAATTCGGCCAGATCGGCGACGTGGTGGCGTCCGGCGACGTCGGGCTCGCCGGTGATCTCGACCAGGAACTGCTCACGCACGGTCCTGAAAAACCTCTCTATCTTCCCTCGCCCTTCCGGCCGATGCGGTGTCGAATGCACCAGGCGCACACCGAGTTTCGCGCACGCCCTCAACAACCACGTGTCTATATAGGCCGATCCGTTATCGACATACACGGCCTTGGGGACGCCGCGCGAAGCCAGCGCCGGGCGCAGTGCGGCGGCCAGCCGCACGGTGTCCTCGGCATACCCCCACCGATAGCCGGGCAGCAGCCGGGAATGATCATCCAAGAACGCGAATAAATAGGTTTTACGGGCCGCGATCGCGATGCCGTGCAGCGCATCCCCGGTCCACAGGTCGTTGGGGTGCTCAGCCTCGAACCGGCCGAACACCGGCGCCGACCCGCAACCGGTGCCGGCGGTCAGCCCCAACCGGTGGAAGTTGCGTTGCAGGGTCCGCTCATCGGGCGCCCAGCCCAACTGGGTGAGCAGGATCCGGCGGATCGCCGCGGCGGTGCGGGCGGGGTTCTCCCGACGCAGCGCCACCGCCAGCTCCAGCACTTCGGCCGGGGTGCGCGGCGTGCATTGGCGCGGGCTGGGCACCAGCGCATCGAACCCGCCGGCACGCCAGTCCCTAATCCACCGATCGATGGTCTGCCGCGAGATCCGCACCCGCCGCCCAAACGGGTCGGTGTGCTCGCGCGACGCCAACTCGCGCACTATCTTTCCCCGCTCCTTGGTGGAGTGCGCCGGCTCGGCGGCCTCCCGGATCAACTGGTACCGGAACAATCCGATCACCCGGGCCCGCTCGGCCCGCACCCTCGCCTCATCATCGCCGACCACCACCGGCCGCCTCCTTTGCTGTCTTTTAAACACACGACAGCGCACAGGATTACGGCCTCATCTGCCTTGGCGGCAGGGTCGACTCGTGTTGCACCCACTCCCCGGGCCAGCCCGACGCCAACAACCGGCCACCGGAGACCGCCACCGCGACTTCGGCCAGCGACACCTCGGGCAGCGCGAACCGGCGCTCGATCACGGACGAGGACGAAGAAGATATCGCCGATTGGTCCGTTGCCGAAGACCGCACGACCGACCCGCGACAAGACCGATGGATATTCAGTGACATACGGCGTTGCATGAGTGACGTACGCGAGATAGGCGACACCGGCCAGCAAGAACCCGAGAATGCAGGCCATCGCGGTGAGCACTCGACGTGCGTTGACGCCCTGCGGCTTTCGGAAGACGTCGACTGTATTTGGAAATCGCCTCAACCCCGGTCAATGACGAACCCCCGTTGGCGAACGAACGCAGCAAGGTCAGGATCGTCGCGCCCATCACCAAGCCGTTGCCCTGCTGTACCGGCACCGTTCCGGCCAGGTGATGCGGGTCGTACACCGGTAATTCCCAAAATATTTCGCGAATGACACCCACCACGATCGTCAGACTGATCATGGCGATGAAGGAGTAGGTCGCCACCGCGAACGGCATTCCCGCTTCCTTTAAGCCACGCAGGTTCAGGTAGCAGATGACAAGCACCACGCCAACCGTGATGGCTAGGCTGTAGGGACCCAACACCGGGATCGCCGACACCACCGCCACCGTTCCAGCCGCCGACTGCACTGCCACCGTGACCACATAGTCGATCAACAGTGCAGCGGCCGCGACCTGCGCGACCCGGGGTCCGAAATTCTCCCGCGCGCCAACGCCGCCAGCCCGGCCTGGGGCAGCAGTTCGATCAAGATCTGCTCCGGGCCGTATGCGGTCGATGAGATTGCGTCCGGTGAAAGTGCCCCAAGCGCAACGGGATTCGACAACTTCTCGGATGTCAGGTTCTCGGTAATCAGCGGCTTTCCCAGAAAGACGCGCTTGGCTATGTCCCCGACAGTCGCCGGGATACGCTGCTTGCCAGTCGAAGTTGTCACGACCACATTCTTTACCCGAGGTTGAGCGCTAAGGAAGCACTTGGCAACGCCTTCGATGCATTCTGCCGCCCGCCCCCTCCACGCGGGTGCGCAAGCTAAGCGAGGCGGCCGGCCGCGGCGGCGACGCGCTCGTCAGTGGCGGTCAGCGCAACCCGCACATGCTGTGCACCGCGCGGGCCGTAGAACTCGCCGGGCGCCACCAGGATGCCGCGCGTGGCCAACCACGGATGCTGTCCCGGCATGGCTCACCGCGGGTGGCCCACAAGTAGAGTCCTGCTTCCGAATAGTCGATAGCAAAACCGGCTGAGCGCAGCGCCGGCAACAGGGCCGCCCGCCGCCGCGCGTACCGCTCGCGCTGCAGCTTTTCGTGATCGTCGTCGTCCAGCGCGGCCACCATGGCAGCCTGCACCGGCGTCGGCACCATCATTCCTGGCATGTCTGCGTACTGCCAGCAGTTCGACGACCAGGGCGGGATCACCGGCGACGAAACCGGCCCGGTATCCCGCGAGCGACGAGCTCTTCGAGAGCGAGTGCAGCGCTAGCAGCCCGGTGTGGTCGCCATCGCAGATGGACGGATGCAGCACCGACAATGGCTCGGCATCCCAGCCCAATCCCAGGTAGCACTCGTCGGAAGCCACCACAACGCCACGATCGCGCGACCACCCCACCACCTTGCGCAGGTGTTCGGCGCCCAGCACGCGCCCGGTCGGGTTGCTCGGGGAGTTCAGATACACCAGTGTCACCGATTGCGGGCCCAACTGGGTCAGCGAGTCCGCGAGCAGCACCTGCGCTCCCGCCAGCCGGGCGCCGACGTCATACGTCGGATACGCCAGTTCCGGCGCCACGACCACATCCGCTGGGCCCAGGCCCAGCAGGGTCGGTAGCCAGGCGATGAGTTCTTTGCTACCGATCACCGGCAGCACGGCCGCCTTGGTCAGCCCGGTGATGCCGAAGCGGCGGTCAAGGGCAGCCACTGCCGCTTCACGCAGCCGCGCAGTACCGGCGGTTGCCGGATAGCCCGGCGCGGAACTGGCGGCCGCCAACGCCTCTCGGATCACCGGCGCAACCGGATCTACCGGAGTGCCGATGGACAAGTCGACGATGCCGTCCGGATGGGACCCGGCCAGCGCCTCCGCCTCGGCCGACGTGTCCCAAGGGAAATCCGGCAGGGAGGCCGACACTCCCCTGCGAGCGGGTGGTACCCCCAGTCGGCCCATCCCGGGCTTCTGCAGCACCGGCGCGCTCAGTCGCCTTCGCCCTGCGGTGGCAGATCCTTCACCACTTGGGGATCGTTCTCGGTCATGCCGACCTTGGCCGCACCACCCGGCGACCCCAGCTCAACGAAAAAGTCGGCGTTGATCTGCGTGTACTGGCTCCACTGTTCGGGCACATCGTCTTCGTAGTAGATCGCTTCGACAGGGCAGACCGGTTCACAAGCCCCACAGTCGACGCATTCATCGGGGTGGATGTAGAGCATCCGAGCACCCTCGTAGATGCAGTCGACCGGGCACTCCTCAATGCATGCCTTGTCCTTGATGTCGACGCAGGGTTCGGCAATTGTGTACGTCACGGACGTCTCCTCAAGGTGTCCTCCATGTAATGCCCCGTGTGGGCTGCCGTTCGCATTGTCGCGGCGGTTCTGGACCGCTTCCAGACAAAGCGTTTGATTACTGATACTAGACGTTGCACATACACGTCAACCACTTGGCACGCCCGTCAGACCGCAGTGCTATGCACCTAGTCGCACCTAGTCGCACAGCGGCGTGGTGTGCCATTTCTGCTGCCCGGATGGCACCGGCGTACGCGACCTTGGTGTCGCTGTGCGAACAGGCCGGCTCGGGCTACCAGTTACCCCCTGGTTGATCAAGTTCCTGTGGGAGTCCGATGCCCCAGAATTGGGGCGAGGAGGACTCGATTCATGGCACGTCGACGGCATACACCGGAGCAGGTGGTCCGCAAGCTTCGTGAGGGTGAACGGCTGCTCGGTGAGGGCAAAGACCTCGGGGAGGTCTGCCGGCATCTGGAGGTCAGTGAGCAGACCTGGCATCGCTGGCGAAATCAGTACGGCGGGATGAAAGCCGAAGACACCAAACGGCTCAAGGAGCTTGAGCGGGAGAATCAGCGGCTCAAGAAGCTGGTCGCCGAGCAGGCCCTCGACATCGACATGCTCAAGGAGATGAGCCGGGGAAACTGGTGAGCCCCGACCGTCGGCGGCGAGCGGTGGTGATGCTCGTCGAGCGGTTCGGGGTCTCGCAGCGGCGTGCCTGCCGGGTGGTCGGCCAACACCGCTCGGTGCAGCAGTATGGGCCGCAACGACCCGATGGCGTCGAACAGCGGCTGCGCGCCTGACTGCGGGAGATCGCCATCAGCCATCCGCGGTGGGGCTGGCGCAAGGCGCACGCCATCGCCAAGTCAGAAGGCCTCGTGGTCAATCCCAAACGCACGCACCGATTGTGGAAAGACGAACGGCTGCAACGTCCGTCGAAGACCCGCAAGCGGCTGCGCCTGGGCCACAGTGCGGCGCACCGGCGCATGGCGGCGGCCCGCCCCGATCACGTGTGGGCGCTGGACTACCAGCACGACCTCACCGTCGACGGCCGCCAGCTGCGTTTCCTCAACGTCATCGACGAGTTCACCCGCGAGGCGTTGGCGACACGGCCACGTCGGTCGTGGAACGCCGATCAGACCACCGGACTGCTCGACGAACTGATCATGACCACTGGCCGCAAGCCCGAACACATCCGAATGGACAACGGACCCGAACTGACCAGTCACGCCCTCGCCGACTGGGCCCGCTTCGGCTCGGTAGGCGCCGTGTTCATCCAACCCGGCGCACCGTGTTCGGGGGCATTCAGGTTGAGCACTTGGGGGTAGCGATCCGGCACTGACGGTGATCAGTTCGTCGGCCGGTCGTTTCTGCGTTTGGTCTTTGTGGTGTCGGGGCGGCACGGTGATCACGTCGTTGTGGGCGGCGGCCCTCCCGATGTCTCTGGGCGGAGTCTGCGGGAGGGCCGTCTTCGCGCTTGGAGGCGCAGTGGTCACGGTAGAGGCAGATGTCGATGTGGTCGAGCGCAGGCTGGCGGCGGGCGAGTTGAGCTGCCCGGCATGCAGCAGCGTGCTGGCGCGTTGGGGGTGGGCCAGGCCGCGACAGCTGCGCGGTCGGGACGGGTCGGTGCGGTTGTGTCCTCGCCGGTCGCGATGCACCGGCTGCGGGGTGACGCATGTGTTGTTGCCCGTGACCGCGTTGCTGCGCCGTGCCGACACTGCGGCGGTGATCGTGTCGGCGCTGGCTGCCAAGGCGTTGCGGCGGCGGGTGGGGTTTCGCCGGATCGCGGCCGACTTGGCCCGTCCGGTGGAGACGGTGCGGGGCTGGCTGCGTCGCTTCGCCGAGCGGGCCGAGGCGGTGCGGTCAATGTTCACGGTCTGGTTGCGCGCGGTGGACCCCGATCCGGTGATGCCTGAGCCGGCCGGCGGGGTGGTCGCCGATGCGGTGACGGTGATCGCCGCGGTCGCGGGCCCATTTCGATGATCGACCCGACATATCACGTGATCGAGGACCCCGCGAAGGCCGGCAGGCCCGGGGACTCCGGGGAATCCGGGCAACGCAGCGAAACGTAATCTTTTGGCCGGATATCGGGCTGACCCGAGGGGTGTAAATGGCCGAAAGCCGGGCAGTTAGATTCGTTAACTAGTGGGCGGTGTACGTCATGCCCGCGGTCGACGGAAAGGACAGCTGTGAAGCGACTGGCAGCCGTGTTGGTGTCCGTGTTGGGTTTCGCATTCACCGCCAATGGTTACCGGGCGCTGACTAAGCGCCCGTACGGCTCGGTTTTCGCGTCGGAACTTCCAATGCAATCGCTCGGCGTCCAGGTCACGGCGCTGGCGGCGGTGGCTGGGGCTGCTGGGCTTGCGCCACGTCGGGCGAAAGGCCGACGAACCGCTGACCGCTGCGCTCGATGCCGGCCTGGGTCCCGAGCGTCGCACCGAGTCGGGCGATCTATGGAAGCGGCCCGCGCCCGCAGGTGCGACCGCGAAGAAACCTGGCGTGGGACGAATGCTGCGGATCTACCGTGACTACGCGCATGACGGCGATATCAGTTACGGGGAGTGCGGCTCCAGGAACCATCTCGACATCTGCTCCGGTCCAGGTCGGGCCAGTGGGGCGTCGGCAACGTCGGAACGGTGGCGCTTCGCCATTTCGTCGGTAACCCTGCGTACGAGGTGGTCGGCGTGCTCTGTAATCGTCCGGAAAAAGTTGGCAAGGATGCCGGTGAGCTCGTCGGCGCCGCGCCGATCGGTGTGCTTGCGACCACCGACAAGGAAGCCATCGAAGCGCTTGACGCCGATTGCGTGTTCTATGCGCCACTTTGGTCCGATCCCGAAGAGGTCTGCCGTCTGCTGCGCGGGGGCAAGAACGTCGTCGCCTCGGGTGGCGCATGGTGGTATCGAACCGAACACAGCAAGGCGGATATCGACAAGATCGACGCAGCGTGTCACGAGGGCGGTACTTCGTTCCACGCAGGTGGTATCAATCCTGGCTTTGCCGGAGACCTGCTCGTGCTGACGCTGGCCCGAATCGTCAGCCGGATCGACGCTATCCACATCTACGAGGTGGTGAATTTCGGCAAGGACACTTTGAAGTACCTGCACGAGATGGGGATGGGGAGCGATCCCGAAGAGTTTCTGGCCGGACCGAATCTCCTGGGGAACGCATGGCCGTTGTTCGCCCAGTCGATGGCCATGGTGGCGGACGGATTCGGCAAGACGGTCGACAAGTACACAACGGATGTAGAGTTAGGGACGGCCACGCGCGACATCCGGTACGAAGGGGGGCCGACCAGCGACATGCCAGGCTTTAAGGGCGTGATCAAGAAGGGAACAGTCGCCTCACAGCATCACAAGTGGACGACTTGGGTGGACAACAAGACCTTCATCACATTCCACGAGATGTACACGATGGACGAATACAATGCCATTGAGCCGCAGCCTGATTGGGGCGGTCACTATCACTATCGCATCGTGATCGAGGGCGACGAACCCACCGAGCTGATCCTCCAAGCGCCTCCGGATGCGCAGGGCAACTACCCGAAGCCGGGCTACACCTGGACCGCGATGGGCCCCGCGAACGCGATTCCAGCCGTTTGTGACGCCCCGCCTGGATTCCTCACCCATAAGGAGCTCGGGCTTGTGCCGCTGCGCGGCCTGGTGCGCTTGTAGCGATTACAAAACCGCTGGGCCCGAATCAGCCGGGAGACGGCGGGAGGATCCCGCGAATCCGGGCCGTGAGCCACGAGGCCACCGCTCAGGTTTTGCGCGCCGTCAATGAGCTTGCGGACCAGGAGGGTTCTCGCTCCGGCGGGTATTTCGTGCGGGCAGTGGGGGCGATGAAGCCACGTCATCCTTGCGGTCGGGGTCGCTGTCACCTCGGTGCCGGCGGTGTCAAAAATCTTCGCCGACCTGAAAATCCTGGACACACGGTTCAGGCAAGACGACTCTGCATCCGTGGCAGATGTTCTGGCACCTTTTCGCAACGGTGGCCTACTTCATCCTCGGGCTCAAGCTTGTTCCACGCGTCATCAAGCGCATCAACACTTCTCGCTGGAATGTCTTTGCGCGGCAGTCGCCCACCGGCTACCCCATAGCGGTCCTGCTGGCATACTGCGCAGTTGTCGGAGCCCTCGACGTCAACCTCGTCTTCGCGGCGTTCCTCGCAGGTTTTGCCGTCGCGCATAGGAAGCGCAGGATCTTCGCCGACGCGCTCGAGGCAATCGGCAAAGTCTCCTTCGCCTTCTTCATTCCCATCTACTTCGCGATCGTCGGCCTGAAGCTGGATCTCATCCGCGGCGTCTCGGTATGGATGATCGTCATCTTCATTGTCGGCACCTGCGCGATCAAAGTGATGTCGGTATCGCTCGCCGGGCGGTTCGCGGGTTTCCGGGGACTTGACCTGATCAACCTTGCGATCACCACCAACGCCCGCGGTGGCCCCGGCATCGTTTTGGCCAATGTCGCCTTCGACGCCGGCATCATCAGCTCAAAGTTCTACACCACACAGGTAATCGCAGCCGTGCTCACCTCCCAGTTCGCCGGTACTTGGCTCGACTACGTCATGCGTAAAGGCTGGCGGGACTGTCTGAACAACGGTGGATCTGATCTTGGTCTGTCACGCCGAGCGTGAGCTTGGCGGGAAGGACTGACGATGTCAGAAACACTCGATCCTGTGGCGATGGAACTGGATCAACGGCAGCTCGCTGAGCAGCTGCTGGCGCAGGCAAAAGAACAGGGTGTCGAGCTGGTCGGCCCGAACGGGCTGCTGAATCAGTTGACCAAGAACGTGCTGGAGACCGCGCTGGATGCCGAGATGGCCGAGCACCTGGGCTATGACAAGCACGACCCTGCCGGGCGCGGCAGCGGGAACTCCCGCAACGACACCAGGGCCAAGACGGTGCTCACCGAGATCGGCGCCGTCGAGATCGAAGTGCCTCGCGACACCAACAGCAGCTTCGAGCCGCAGATTGTCAAGAAGCGTCAGCGTCGGCTGACGGGTATCGACGAGATCGTATTGTCACTCACGGCAAAGGGATTGACCACCGGTGAGGTCGCTGCCCACTTCGCCGACGTCTACGGCGCCACGGTATCCAAGGACACGATCTCGCGGATCACCGACAAGGTAGTCGCCGAGATGACCGACTGGTGTAACCGGCCACTGGTGCCCGGGCGGATTCCACTCATCGTTGCGAATCAGTGAAGTGTGTACTGACGCTCCCATCGTCGCAGAAGTTCGGTCGGGGTGTTGTCCTTGAGGCACAGTCGTGGGCGGTCGTTGAGTTCATCGGCGATCTGCCGGAGTTGGCCGTCGTCCCAGATGCTGAGGTCGGTGCCCTTTGGTAAGTATTGGCGTACAAGCCCATTGGCGTTCTCATTACTTCCGCGTTGCCAAGGTGAGTGTGGGTCGGCGAAGTAGATCTTCAGCCCTGTCGCCGCCTCGATACGTTTGTGATGAAACATCTCGTTGCCCTGGTCCCAAGTCAGGGTCCGGCGCAGTTTGACCGGCATTTGGGTGAACGTTGCGATCAGGGCATCCCCGACATGCTGTGCCGAATGTCCATTCGGCAGTCGAATCAGCAGTGTTAGACGCATCTTTCGTTCCACCAGCGTTGCGACCGCCGACCGCTGCTGGGCGCCGACGATGAGGTCACCCTCCCAGTGGCCCGCCTGTCGGCGGGTTTGGACGCTCGCCGGTCGCTCGTGGATTGACCGCAGCTTGGTGAGTTGTTTCAGCGCGCCGTCGATAGCGCGATCCGTACCGAGGCCGACACGCTGGAGCGCATTCGGCGGCTGGCAGCCCACTACGACGACGCGACGATCGCGCGTCTGCTCGCACGGCAGGGCGTGATGACTGCGACCGGGCTGGCGTTCACCCGCGACCGGGTTGGCAGCCTGCGCCGCAAACACGGTATCGCCGGGCCGACCGAGCCTGTCGTACCCGTCGGCGACGATGTACGCATGGTCAGTATCGCCGAAGCCGAGACGCTGCTGGGGCACCTCCCGCGCCACTCTCTACCGGTGGCTGGCAAGCGGCTTCATCCACGGCGAGCAACATCGCCCTGGCGACCCGTGGCGGATCCGCATCGACCCCGAGCTACGCGCCAATATCACCCCAGACACACCCGACGGATGGGTTGGGCTCGAGCAGGCTGCCCGCCGACTCGGCGTGGCCAAACAGACCGTCCTGGATCGAATCCGCCGCGGAGAGCTCAACGCCGTCCACGTCAACCGTGGCCAACGCAAAGGCCTGGCCATCCAACTGCCGCTGCCGGAGGAGACCTTGTTCACTACGGCGCCATGAAACGCCGACAGCAGCTTGTCGCATCCGGTCCAGAACACCTAATCGCACCACCCGCCCGACCATGAACACCAACAACAACGCAGCATTCGGCCCGAATCTGGACCGAATGAGACAAACGACGAAAGGAAATTAGCAGTGAGAACCGGGATCGACCGGGTTGCCCAACTCGTCGCGCAGATCGATCGTTCGCTTGCGTTCATGAGTCTATGCGGTAGCGCTGACAGGCTCGGTTGGCACCAGGCCAGTTTCGGTGTGATTTTGCGGATTCCTTTGCGGCAGTTCGGTCGGTGGGTCGTGCAGCGATCTGCGTAGGTCGGCCAGCAGCCGCAGCCCGGCCGGGGTCATGGTGAACCCGCGCCATCCGGCGCTGGCGCGGTCGAGTACGGCCCACACCAGTGTGAGGCAGGAGTACTCGCCGGGCAGGCGGCCGATCACCTTGACTCTGCGCCGTGTTTCGCCGAAGGTGCGTTCGATGAAGTTGGAGTGTCGGGCCCTGGGCCAATGCTCACGGGGAAACCGCAGGTAGACGGTCAGCGAGTCGCGGTCATCGAGCAGGGCCCGCACTGCGGCCGGGTAGGAGTCGCGCCAGCGCTTGGCGAACGCGTCGGTCCTGTTTTGGGCGAGTTTGACCGCGGCGATGCCGGGTTCGACATCGGCTGGTAGGTCGAAGACCGCCCAATAATCGGCTTTGACGTCAGCTTGGGCATTCTTGGGCACCTTGGCCAGGATGTTTCTGGCGCGATGAATAAGACACCGCTGCCGCAACGCCGCGCCCATGGTGGTCTCGACCGCGCCGATCAGCCCGGGTGCGCCGTCGCTGATCACCAGCAGTGGGCACGCCAGGCCGCGTTCGCCGAGCCCGCGCAAGAACCCTTCCCAGGCCGCACCGGATTCCGAGGAGGCCGCCTCAAGCCCGACGAACACCGGTTTGCCGTCGGTGTCGATACCCCACGCGGCCAGTACCGGCTCGGCTGAGGCGCCTGCGTGGTATTTAAAGTGCGACCCGTCCAGGAACAGGTAATCGAGCTCGACGTCGTCGAGGCGGCGAGCGCTCCACTGCTCGAACTGAGCCGTTGATGTCCTCGCAGATGCGCGACACCGTCGACTTCGACACCGCGGCGGCCTCGCCGAGCGCTTCGACCAGGGTGGCCTCCACGTCGCGGACCGACAACCCGCGCACGAACCCGGCGATCACCAATGCCTCCAATGCGTTGGTCTTGGTTACTCCCTTGCCGAACAGCTGGGAGGCGAACCGCTCGGTGGTGCCGCGCATCTTCGGCCGTGCCAGCGTCACCGGTCCCGCGGTGGTCTTCACCGTGGTCGGGCAGTATCCGTTGCGCATCCCGGCGCGGGCGTCCGCACAGCTCGCGGTCCGCTGGTAGCGGTCCCGGCCCAAAAACGCGGCCACTTCGGCCTCGATGGCGGTCTGCAGCAGCAACCGGGCACCAAGCCGGGCTACTTCCTCGATCGCGCCCGCCAGGTCCTCGCCGCCGGCGAACACACCATCAATTTCTGCCTGCAACCGCTGCACAGGCGATACCCTCTTCGACACGGACGTAGGCTCCTTCCATCAGACTGGCCGGTCTTCGAGGGAACCTACGTCCGGATTCTTTTACACCGCGGCAGGGACACGACCTAGCGAGGACACTGTCGCGTTAGAGGACTTGCTGACTCCGACACTCGACGAGTTGGACACGATCGCTACCAATGGCGGTCTGGCGCGGGGCGTGCCGACCGGATTCGCTGATCTCGATGAGATCACCTGCGGGCTTCAGCCAGGAACCATGGTTACCGTTGCGGCTCGTCCGGGCGTTGGAAAAGTCCGTTCTAGCACTGGATTTCATGCGATCGTGTTCGCTCAGACATCGGATGGCCAGTGTCATCTTCTCGTTGGAAATGAGTAAGTCCGAAATTGTGATGCGGCTGCTGGCGGCCGAAGCGAGGGTCAAACTTGCGGATATGCGTTCGGGGCGCATGAATGACGATGACTGGATCCGGGTGGGCGGCACCATGAGTCAAATCAGCGATGCCCGGATTCGGCCCGTTGCTAGGAGGCGGAATTCGTGGCCGCGATTAACGGCGATCTAGCTAACTACGAGACCGTGGATAGGCTTGCGGGCATCGCTGGTCTTTCACCAGTGCCACACGATTCCGGGCGCGTCACGGGCAACCTGAAACGTCCACGCAGGTATGACCGGCGCTTACTCCGAGCCTGCTACATGGCTGCCCACAACAGTCTCCGCACCAGTCCAGCATCGCGTGCCTTCTACGACCGGAAACGAGCCCAGGGCAAACGCCACAGTTGTCGGCGTCGTCTGAAAACTGACCCCGTGTCGACGCGGTGGTTTCTAGGTGCGGTCGCAACACTTCTCTAGATTCTGGAGGTTGTGTTGGCATCGTCGCGTCGGGTGAAGAAGGGGCCGGGACGTCGTCCGCAGTCGGCCAAGCGTCAGCGGTTCATGGAGTTGCGGGCTCGCGGGTGGAGCGTGCGGGCCGCGGCCCGCGAAGTCGGTGTGTCCCGGTCCGCTGCGACGAACTGGACACGCGGTTACAAGACCTACCGCAACGGCGTCGCGGTCGGGTTCGTCCCGCCGCTAGATCGACTAGCGGTCCGCCAGATCAGCACGCGATACCTGTCCCAGGACGAGCGCATCGAGATCGCCGATCTGCATCACTCAGGGCTGAGGGTGCGGACGATCGCCACCCGACTCGGTCGAGCGCCGTCGACGATTTCGAGGGAGCTACGGCGCAACGCACCAGCCGGCCGCGGATATCAGCCCTTCGATGCCCACCGGCGAGCCACCGCGCGACGAGCACGTCACCACCGCCGTCGGGTCGACACCAACGACCAGCTCGGTAACGCGGTCGCCGAGCTGCTTCTTCAGCGTTGGAGCCCCCAACAGATCAGCCGTCACCTCCGCCACCGCTTCCCCGATGATTCATCGATGTGGTTATGCCACGAAAGCATCTATCAAGCTGTCTATCAACCGAATTCACGTTTCATGCGGCCCTCGCGATTAGCGCCGCACCGACGCTCACCGCTGCGCACCGGTCGAGATCACCGCCGAGCGCATCACCGCCAGAGTTGCCGGCGGCCGCGGTTCCAGCAGCCGATGCTCACCATCCACGACCGGTCCTTCTCGGCTGTCGACCGGTCTGAAGCCGGCCACTGGGAAGGCGACCTTATCATCGGTAATAACCACCTCTCGGCGATCGGCACTCTGGTCGAACGCCAGACCCGGATGCTGCGGTTGGTGCATCTGCCTCGCAGTGACGCCGACTCCCTGCACGCGGCCTTGGTGGCCCGCATGAAGGATCTGCCACCCACGCTGATGCGGTCGATCACCTGGGACCAGGGCACCGAGATGGCGCGCCACCTTGCCACCACCGACAAGCTCGGCGCGCCCGTCTACTTCTGCGACTCCAGATCACCCTGGCAACGCGGCACGAACGAGAACACCAACGGACTGCTGCGCGACTACTTCCCGAAGGGCGTCACCCTCATCAGCCACCCGCCGGAGCAGTTGTTGGCCGTCGAACACGAACTCAACCATCGCCCCCGCATAGTCCTCCAAGACCGTTGCCCCGCCGATCTATTCGCTGCCCTGTTAGTCTCGAGTGATCCGTCGGTGTTGCGACGTTGAGTAGAACCCACCCCGTCGTCAACACCTCACACCTCTGCCGCGTGGACCGGCCCTAAGTCATTACGTCACGATCGGCGGTGCCCTTGCCGCCGCGAGTGTCCTCACGGGCAAGACACTGCGAAAAGACCGCGCTTCGGCTCCATCACCGCGAATCGTGCGTCGGGCACGGCCACTCGGATGTCGGTGGAGCTCAACATCTCGAATCCGCCCGCCACGCAAGTGCCGTTGACCGCGGCGATGATCGGCTTGTACACGGGGAAGCGATGCAGGACGGCGTGGATTGCGTCGAGCTTGTCCAGAGAAGAATCCGGTTATTTCCGCCTGCATCCTGCGAGTCCGAGGCGGTCGGCGGCATCTCGCTGCCAGATGTCAAGACCCGGGTGTGTGCCAAGTGATAGGTCGACGGTTCGGCGTGTTCGTTGGTCGCCTGTCTACCGGATGGTCATGAGGCGTTCGGTCGGCCCGGTGCCTGTAGGTGAGGGCGGGGTGGCAGCCGCGGTGTTTCTGTGGGACGGTGCGGCGCTCGATTCGATGCGGCTGCGGCCGGTGCTCATTGCGGCGATCCCCTCTTCGGGTGCGTTTCAGTAGATCTGCATATCAGTACGCGGATCAATGAGGGGTCCTGCACTTGGGCCCAAGGTGAGGCGCGGCACCCCTCGCGCGTCGTCGGCGATGAGTTGCCGGCGGGCGTCTGCTGAGGCCCTGTGTTGGGGACGGTCTAGGTGCACGCGGCGAGGTGTGACTGCTGATCGGACTACGCAGGGAGCGATTTTTGGCCAACAGCGATACTGAATTCTAGGAAGAAAGGTTTCTGCAGATATCGGGCACCAACCGAGTAAGTCTAGTTTGCTGGCACCTTGAAACTCTGATAATCGTAATCAAGTCAGACTCTGGCCTGAATGATTCACGTTGTGCTCGATATCAGTAAGTACGCAGACGCGAATTGGCGCATGTCAGTACACCAGTACATGGTTGTTGAACTGCTGCAATATACGATTGTAGGTGTGGAAGTCAGTGTCTACTGAAACACTGAATTTATGAATATGAATCACTTTGCAAACAAGGTAGCCCAATTGGCTTGACGCTCACTTTCTGTAGTAGCTAAGCTGCATTGCATAGCCAAAGTTCATACAGCTGGTGGCATTGCTATCACCAGTTGTGGGAATCCAGTTGTGGGAATGGAGGTGAGCCCCATTACCACCTAAGTGACTGTGCAACGCACGACAAGTGCGCCGATCATAACGCGATCATCTAATGATCCATGAATTCGGAGGGGAACATGACTTGCAAGACACGACGCCGCGGTATCACGATCAAGCTCGGCATGGCCGCAGGTGCAGCTTTGGCCGCCGGGCTCATCCCGATAGCCAGCGCGGGCGCTGCCTGGGCGGATGAGCCAGACCCAGGGATCACAGTTGGGGGCGGCGGGTCTGGTGGAGTGTCCACCCCGATCGGTGGGGGCAGGGCGTCGACCGGCGGGTCCGGTGCTTTCAACGACAATGGCGGCGGCTTCGGTACTGGCACGTCGGGCGGTTTGACCGGTCCGGGCGGCGCTGGGAGCGGCGCTTCCACCGGCGCGGGCGGTGGTTTCACCCTGCCGGGATTGCCGGGATTTTGAGGTAGGCACCGCAGCGGGAATCGACATTTGACTGGCGTGGCCGCTAGCCGCGCAGCAACGGATGTCGACATGCGGGGCAAGCGGATGACGCACCCCGAAGCCTCGGGAGAGGACGTTTGCTTGGTGATTGGGACCGGTCGCCCGAGTCGCGCACATCGTGGCCGGGCGACCGCTCGTCGGCGGGTATGACGGTCGGCTGCCGAACACGCCTGGCGCCTGAAGCGGCCACCCATGATGCCGAGCATGAAGTGTTGGTGCGCGCGCCCAGTCGCAAAGTTCGTGATTGAGGCGTGACGGGCGGTCCACCACGCAACGCACGATGTCTTGCGGTCACCATCTTCCACCATCTTCGAGCCAGCGCCCGTTCACATCCGGCCACCAGGTCGGCAACGGGTCGCGGCGGGCAAGGCGGGCGGTTCATCGCGCTGCGCGGCGCACCAGACAGCGCGGTCGCCTGGCGTTTCTGCCGCGCGCTCGCAACGCCGTGCTGCGCCGCTTCATCGAGGCTGCAGTGCGCTTCATCGCGTCGATGAGGTCCTTGGCCTCGCCGATCGATTCCAAAATGGCCACCCGAGCTTGGCCGGCCTCCTTAGTCAGTGGTGTGCCCAGGAGCTGCCAGTCCGAGCGCAGCCAGTCGCGCGCCGCGCTGAGCGCTGATCTCACTTCGTCGATGCAGGCGCGGGCGTTCTCGAATAGTTCGGGACGAGTTGGCAGGTCAGCCATGGGTTGTCCTTTGCGGCGGGTTGTAGCGGGAAGCCGTGGGAGTGACGGCCGGCGAGGTTTTCACCAGCCGGCGTAGGCAAGGGGCAGGTCGGCGATGACTTGTCGGCGTGATTCGTCGAGGCTGGCAGCAATGTCGCTGAGGCCATTTGCGCCAAGTGATCGCAAGAGTTCGCCGCCGGGCTCAGAGTTGTAAAAGCTCACCATCGCCGCAAGGAACATCGCTTCGCCCGAGGACAGCCATCCGATAGCTGATCGGATCTCGTCGACCCTCGGCGAGAGATCCCACTTGCTGGTCGCGCTGTCCGGGGAAGTCTGGCCGTCGGCGAACCATCGGGGACCGGCGATCTCTACACCGCGCTGCCACGCTTGAAAAACGGTCTCATCATAGAAACGTGCTGACATGTGTTCTCCTCCTGAGCCGTTCATGAGTTTCTTCCAGGTGTGACAATCGTTATCCCGAGGGCACGGGCGGCGTCGCTGAGTCGACTGTCATAGGCGACCATGGCGGTCAATGGTGCTGTGGATGCGGCGATTTGAGCGGTGGCCAGGTGTATCGCATCGAGCGAGCGCAGCGCCGGATCGGGGTAGGCGGCCGCGGTGGCGCGGATGACCTGGTCGATTTCGAACCGATCCAGTCTGGCCAGCACAGAGGGGACAGCAGATAAGCCATTTGGGGCGACTGCGCGGATGGCTCTGGGGAGCTCCACTTCAGCCAAGGCAGATGTTATCCAACGTGTTTCGGTGCGTTCATCGAGCCAGTCAGCTAGAGCATCAGATTCGACTTCGATCCGGATCAGCTTGACCAGAGCCGAGGTATCCAGGTAGATCACCGGCTAATACCTTTCCTCGGCGCGCAGACGTTGCAATAGCGCGCCGGCGTCGAGATTGTCGTGCATCGGAACGGTCGGCCGCGGGGCTGGGCCGGCCAGCGTCGCCGGTTGCACTCTGCCGGCAGTGATCAACGCATCCAGTGGGCCGGCGGTAGCGGGGATTATTCGGGCGATGACTTCCCCGCGCTCAGTAAGCGTGATCTCTTCGCCACGCTTGACGCGGGCCAAGACCTTTGCCGTCTCTTGGTTGAGCATTCGGAGAGGTACTTCACTCATACCAATAATGTACTACATAGTTGTACTACATGCTATGGTGGCGCAACTGGTTCGGAGCGCCGGCGGCCCATGTCCACACGCCCGCCCCCGAGAATCAACCTATCGACGAAGCCGTTCAGGAACTCCGCGCCGGCCTCGTCGTCAGGCTCGCGGCCATCGGTGCTCACAAAGGGACCTATCCGTCTCTAGCTGCCTTGTCAGCTCAATTCTCACAGGTGGGGCAGAGATATGCGACGGTCAGCGCGTGGTTATACGGCCGAGCCATTCGCTTGATGCCGGCGGTCTGCGGGCGGTGCCGCTCAGTCAGTGCCGTCGTCCCGACCATTGGTGGCGCCAGCCACTCGGCCAACCTAGCCTTGACCTGCTCCGCCTGCTCCCGACTGTGGCACATGTCGTTTGCCATCTTTCCGAGTGTTACGCGGCAGGGGAGAAGGTCAAGTCCAGGGACGTGGTGTACGACGTCGTCGTGTGATTCTTCGACTTGGTGGTTTAGGCGGTCAGTGCCGCCGGGGTGTCCTCCTGTTCTGTTGATGGCGTGTGGTCGGCGCGGGATTTGCTGAGGACGTCGAGGCCGAGGTAGCGGCGGGATTCGGCCCATTCGTCGTGTTGTTCGGCCAGCACCGCGCCGACGAGGCGGATTAGGGCGTTGCGGTCGGGGAAGATTCCGACGACGTCGGTGCGCCGGCGGATTTCCTTGTTGAGTCGTTCTTGTGGGTTGTTGGACCAGATCTGCCGCCAAATTTGTTTGGGGAAGGCGGTGAAGGCGAGCAGGTCGGCGCGGGCGTCTTCGAGGTGGTCGGCGACCTTGGGGAGCTTGTCGGCCAGTGCGTCGATGATGCGGTCATATTGGGCTGCAACGGAACCGGCGTCAGGTTGATCGAAGACCGAATGCAGTAGTGTGCGTACCCACGGCCACGATGATTTCGGAGTGATGGCCATCAGGTTGGTGGCGTAGTGGGTGCGACACCGTTGCCACGATGCCCCAGGCAGGGTGGCGCCGATCGCGGCCACCAGACCGGCGTGGGCGTCGGAAGTGACCAGACGGACCCCTGATAGGCCGCGGGCGGTCAGCGACCGCAGGAAGGTCAGCCAGCCGGCCCCGTCCTCGGCGGTGGTGACGTCGATGCCCAGGATTTCGCGGTAGCCCTCGGCGTTGACCCCGGTGGCGATCAGCGCGTGCACGTTGACCACCCGGCCTGCTTCGCGAACCTTGAGCACCAGGGCGTCAGCAGCCATGAACGTGTACGGGCCTGCATCCAGTGGCCGGGTCCGGAACGCCTCGACCGCGGCGTCGAGCTCTTTGGCCATCACGCTGACCTGGGACTTCGACAAGCTGGTGATGCCCAGAGTCTCGACGAGTTTGTCCATCCGCCGCGTCGAAACGCCCAGCAGGTAGCAGGTAGCCACCACCGTGGTCAGGGCCCGCTCGGCGCGTTTGCGCCGTTCCAGCAGCCAGTCCGGGAAGTACGAACCTTGCCTTAGCTTGGGAATCGCCAGATCCAATGTGCCTGCGCGGGTGTCAAACTCGCGGTGCCGATACCCGTTGCGGGAATTGGTGCGCTCGCTGCTGCGCTGGCCGTAGCCGGCACCGCACACCGCGTCGGCTTCGGCGCCCATCAGGGCGTGAATGAAGGCGGCCAACAACTCGCGCAGCACATCAGGGTGCGTGGTGGTGAGTCGTTCGGCCAGCACGGCAGACAGGTCGATATCGTGGGCAATGGTCAT

Protein sequences of DBSCAN-SWA_2

>NZ_AP022614|5192721:5295930|5235428_5236277_+|WP_065517438.1|DBSCAN-SWA
MVQGSLNGVRIVSLAVNIPGPLAAARLARFGASVTKVEPPTGDPLAAVAPGWYAELASKQTVLVLDLKDAGDRAKLDVELTSADVLLTAMRPSALRRLGLDDAHVRYPGLCHVEIVGYDGDLEERPGHDLTYQATHGTLQPPLMPAVPVVDLLGAERAVSGALLALLDRPNSGAGQHVRIVLADAAADAGAAVRYGVAGPGDPLGGATPTYGIYASADGYIALGAIEPHFQKRTLEVLGAADTHEDLARVFAGQSTRHWEEVAETVDIPIVGIRTPEQGVEH
>NZ_AP022614|5192721:5295930|5232446_5232992_-|WP_065517439.1|DBSCAN-SWA
MFPHDSRRERLIVRIENLLPARVPLAVTAAAEHYTATLAERMLGEEIQKIPGDPEVRNLLNWHAVEELEHKSVAFDVYRAVDGPEWLRIGVMAVLYILTIPVVSIGVLLSILADPRGWRPIKVARQTRAVFRDPLVQGLMADLRMYLKPGFHPDDIDTTALVQQWRQELFGDDGALVGHLK
>NZ_AP022614|5192721:5295930|5230847_5232425_-|WP_007168414.1|DBSCAN-SWA
MSTTIDIEQLPTVERVTPDHEVVIVGAGFGGIGAGISLQRRGIHDFVIVDKWDQVGGTWHANTYPGVAVDIPSFVYSFSYEQRGDWSRIFAPGYELRDYASDLVDKYGLAQKLRLNTTITSAVLDERNSLWRLTTDADQEITGRNVVMAVGGLERPKMPDIPGLDEFGGVLMHTALWDHDVALAGKRVAVIGTGATALQVVPAIVDEVEHLTVFQRTPIWVFPKPDKEVTSAIRWVLGRKRIRSGIRLVGTVATEVGMAGMWVGPQWLTNASRRMLEVPTRRWMRRQIDDPVVREKLIPRYGLGCKRPSMSNDYLRTFNRDDVSLVTDAIECITKKGVRTADGVEHEIDVLICATGFKLWEAGAVPPFPVIGRGGVDLGRFWSEQRYQSYQGVSVPGFPNMFSITGPYGFVLGSYLWMIEATSAHLSRAIAEAKRRGATVCEIRQEAHDEYFRKCLKRQQNNFLFTPACAGSNTYYINNQGDSPFRPSTHGEMYWQNRYYNLDVYRYSRGVAVLDAAAAMTKESL
>NZ_AP022614|5192721:5295930|5241089_5241848_+|WP_007168427.1|DBSCAN-SWA
MDIAASSAVVTGGASGLGLATVETLARSGARVVAVDLPNANTDALSLLGDTVRFAPADVTDEDAVTRAIEIANADKTLRIIVNCAGVSDGTKTVSKKGPFPLDAFEKVIKINLIGTFNVVRLGAYAMSQNDPVGGERGVIVNTSSGAAFDGQIGQAAYSASKGGVMAATLPIARDLSSYLIRVNTIAPGLFETPLLNSLPEAALTALKALTLHPNRLGDPAEYAHLVVAIVENPMLNGETIRLDGAVRMPPR
>NZ_AP022614|5192721:5295930|5232978_5233353_-|WP_080576328.1|DBSCAN-SWA
MVASQAMAAKSGTAAEKVAESTYPKARRIRFWFGDPEPMDHHFVEGNIVFSHLVALLSGVFPPGEELFIRSVRRFADQMTDPVLMKRVAGFIWPGVGARPGTPPAQREAHRDGLPDCPAVYVPA
>NZ_AP022614|5192721:5295930|5229897_5230851_-|WP_007168413.1|DBSCAN-SWA
MKFNRLRPRLVVVTGAGSGIGRATAIRFAKLGAHVVVSDIDLDAAQATTAMIRGYGLGASAAQLDVTDPDAWAVFGRDVLADHGYTDVLVNNAGILVGGHFLQLSPSDWDRQLGVNLMGVVHGCRVFGAQMVERGGGHIVNIASAAAFTPTPVMAPYSVSKAGVKMLTECLRLELGPRGIGVSAVCPGVINTNIADRAIVVGVDQNLIEQGKQFTKKLQEFSEKFRVSPMSSDLVARAVVRAVRFDLAVVPVRTEAWLGYFMLRIAPGVNRRMMQPFSVDAFQRLGARLSKTVGAADQGELAAGGAEAAAPVTSTGK
>NZ_AP022614|5192721:5295930|5239131_5239908_+|WP_007168425.1|DBSCAN-SWA
MNKQILRSTRDGAVALLEINRPKSKNSLNDELLGAMGAELAALRSDTAVLAVVIAGAHGMFCAGADITAFDEIRARPLVTGESNESFWSILAAFPKPVIAAVETYALGGGCELALACDIVIAGESGQFGLPEVKIGAIPGAGGTQRLIRAIGKSKAMAMLLTGDSIKAQEACDAGLVAEVVADGEAVPRALAMAQRIATNSPLAVALAKDAAVHAFQTSLTQGLEHEKRNFYVAVHSADSHEGQAAFLAKRAPQFTGK
>NZ_AP022614|5192721:5295930|5289522_5290758_+|WP_085272092.1|transposase|DBSCAN-SWA
MKKGPGRRPQSAKRQRFMELRARGWSVRAAAREVGVSRSAATNWTRGYKTYRNGVAVGFVPPLDRLAVRQISTRYLSQDERIEIADLHHSGLRVRTIATRLGRAPSTISRELRRNAPAGRGYQPFDAHRRATARRARHHRRRVDTNDQLGNAVAELLLQRWSPQQISRHLRHRFPDDSSMWLCHESIYQAVYQPNSRFMRPSRLAPHRRSPLRTGRDHRRAHHRQSCRRPRFQQPMLTIHDRSFSAVDRSEAGHWEGDLIIGNNHLSAIGTLVERQTRMLRLVHLPRSDADSLHAALVARMKDLPPTLMRSITWDQGTEMARHLATTDKLGAPVYFCDSRSPWQRGTNENTNGLLRDYFPKGVTLISHPPEQLLAVEHELNHRPRIVLQDRCPADLFAALLVSSDPSVLRR
>NZ_AP022614|5192721:5295930|5194406_5195642_+|WP_042909891.1|transposase|DBSCAN-SWA
MTIAHDIDLSAVLAERLTTTHPDVLRELLAAFIHALMGAEADAVCGAGYGQRSSERTNSRNGYRHREFDTRAGTLDLAIPKLRQGSYFPDWLLERRKRAERALTTVVATCYLLGVSTRRMDKLVETLGITSLSKSQVSVMAKELDAAVEAFRTRPLDAGPYTFMAADALVLKVREAGRVVNVHALIATGVNAEGYREILGIDVTTAEDGAGWLTFLRSLTARGLSGVRLVTSDAHAGLVAAIGATLPGASWQRCRTHYATNLMAITPKSSWPWVRTLLHSVFDQPDAGSVAAQYDRIIDALADKLPKVADHLEDARADLLAFTAFPKQIWRQIWSNNPQERLNKEIRRRTDVVGIFPDRNALIRLVGAVLAEQHDEWAESRRYLGLDVLSKSRADHTPSTEQEDTPAALTA
>NZ_AP022614|5192721:5295930|5281458_5281614_+|WP_154074411.1|DBSCAN-SWA
MSPDRRRRAVVMLVERFGVSQRRACRVVGQHRSVQQYGPQRPDGVEQRLRA
>NZ_AP022614|5192721:5295930|5261308_5261740_+|WP_007168443.1|DBSCAN-SWA
MPADNSIHLIHAAQQRHEHTRAKAIAAMHELDRTGALLTFESVARHAGVSRSWIYTQTDLKDEIRRLRTQHRPEPSTPLPARQRASDDSPRQRLEIANRRNRELADENRRLRRQLACALGQLRDDTGRHHEPTHRDSVTIGPC
>NZ_AP022614|5192721:5295930|5249811_5250330_-|WP_007168435.1|DBSCAN-SWA
MLDGRRDDSMRRRRRVLAAIDQAAAAGDRLSATAIARAAAVDRTFLYRHPDLLEKIHALQADPVPSEHTGPGVTRASLQADLLAAHERAARLGARIQQLEKRLSEALGEQTWRESGLGARTDIDALHQRISQLEQHNLDLKQQLDEREEDLAAARAANRELMARLNTPTRLR
>NZ_AP022614|5192721:5295930|5197795_5198236_+|WP_007168380.1|DBSCAN-SWA
MEFAQFNQQIAKELQNAAATTGGLSKYLDFRHTEFAAGRLVVQMDARDDLLTPFGNLHGGCLSAMVDHCLGVVFYPVIPAGSWVATTEFKLNLLQPVSSGVCVAVTEIIALGKRSGVARIDITNDGRAVCAAQGTVTVVSPRGNSS
>NZ_AP022614|5192721:5295930|5293932_5294205_-|WP_033711258.1|DBSCAN-SWA
MSEVPLRMLNQETAKVLARVKRGEEITLTERGEVIARIIPATAGPLDALITAGRVQPATLAGPAPRPTVPMHDNLDAGALLQRLRAEERY
>NZ_AP022614|5192721:5295930|5281183_5281462_+|WP_007168468.1|transposase|DBSCAN-SWA
MARRRHTPEQVVRKLREGERLLGEGKDLGEVCRHLEVSEQTWHRWRNQYGGMKAEDTKRLKELERENQRLKKLVAEQALDIDMLKEMSRGNW
>NZ_AP022614|5192721:5295930|5258232_5258895_+|WP_163670915.1|DBSCAN-SWA
MGRRREARISAHQFSLAGLPELVRFELLYALQRRDEAPPPLDPLQVRILISRLVGASSLRHADPEAVCESGGVQYNSAIKGLFRDLRRHLERAWTQYTGTDPYAGNVWRVELLDLQSNGSRRWPATKGTIDFGPIELGWLREVLKDWARNTRPYLQGLRQALRACHVASQTLVACGRADPASLGAGDFVLVEQAIVEQRRTDGSPTPPHTAPSCCGCSVR
>NZ_AP022614|5192721:5295930|5287318_5287507_-|WP_167310147.1|DBSCAN-SWA
MWAVLDRASAGWRGFTMTPAGLRLLADLRRSLHDPPTELPQRNPQNHTETGLVPTEPVSATA
>NZ_AP022614|5192721:5295930|5281689_5282139_+|WP_007168470.1|integrase,transposase|DBSCAN-SWA
MVNPKRTHRLWKDERLQRPSKTRKRLRLGHSAAHRRMAAARPDHVWALDYQHDLTVDGRQLRFLNVIDEFTREALATRPRRSWNADQTTGLLDELIMTTGRKPEHIRMDNGPELTSHALADWARFGSVGAVFIQPGAPCSGAFRLSTWG
>NZ_AP022614|5192721:5295930|5256580_5257381_+|WP_163670911.1|integrase|DBSCAN-SWA
MVLDTGLVMHREASDFLRALHGAGRSIHTIRAYAGRVASFLGWCADQGVEWSSISLPGLARFKHFIEATPRRDGRLRSGATVNAILTAVCEFLRFCARTGVIEQAVANRLSEPRWLRFTPPGFDAGESGQFRMVRTRTLKARAEAVFPEAFTPEQAERVAACCRRPRERFMVALLRDGGLRIGEALGLRRSDLHLLPDSRRVGCTVLGAHVHVRHRANPNGALAKSRFPHRADEPGGAVDVRGLPIRTYGDPRRRRLRHGVCQPLP
>NZ_AP022614|5192721:5295930|5268843_5269737_+|WP_007168453.1|DBSCAN-SWA
MAELSFDGRVAIVTGAGNGLGKEHAMLLASRGARVLVNDLGGSVAGVGADLTAAEAVAQEIEAAGGIAVADGHSVATREGGAAIVQAALDAFGRVDIVVNNAGILRDKSFHNLTPELLDPVIDVHLYGTIWVTQPAFLRMREQGYGRIVNTSSAAGIFGNFGQTNYGAAKMGVIGFTRVLAQEGAKYNIKVNAIAPMARTRMTEELLGPIAKKLDPALVAPVVAYLCHESCDLTSRIFSVGGGRVAEIFISVTKGFSSPTLDIEAVQDNLEAICDREGYQTPTQANDEIGLVLQALG
>NZ_AP022614|5192721:5295930|5224164_5224440_+|WP_007168406.1|DBSCAN-SWA
MSTVGVRELRQRASELLRRVEAGETIEITDRGRPIALLSPMPEGGPYQQMLASGGIERATLDFDDLPEPVRLKTGIELPSVTLARLREHER
>NZ_AP022614|5192721:5295930|5211672_5213196_+|WP_007168396.1|DBSCAN-SWA
MDHSDKHRFEIIVIGAGFSGIGMGIKLLKAGFSDFLIVDEADDVGGTWHWNTYPGIAVDIPSYSYQFSFEKRSSWSRTYAHGNELKDYARHCAHKYGLSPRIRFAVKVTEAWFDEDATLWRLHTAAGQDLSARFVINASGVLTRPKRPDISGVDDFGGITMHTSRWDHNEDIAGKRVAVIGTGASAVQLIPAIAKDVKALTVFQRTPIWCLPKLDFPVPRLARGFLKYAPGGQLAARAASQTFVEVTFPVAAHFHTAIPLASLIERAALRYMRSQVTDPAVRQKLTPRYALGCKRPSFHNEYLATFNRDNVHLETSPISHFDAAAVHTVDGRSHEIDVLILATGFKVMEPENMPTYSLRGIGGLDQAKWWDENRLQAYEGVSVPGFPNHFSIFGPYGYNGSSYFTLIEAQTRHIVRCLHHARSRHANYVEITRQANDRFFAEMLKRRHRQVFWQPSCATANSYYFDKHGDVPLRPTTTLESFWRSRTFDLGDYSFERRTTEKVLSSS
>NZ_AP022614|5192721:5295930|5286907_5287189_-|WP_136244823.1|DBSCAN-SWA
MLVFMVGRVVRLGVLDRMRQAAVGVSWRRSEQGLLRQRQLDGQAFALATVDVDGVELSAADSIQDGLFGHAESAGSLLEPNPSVGCVWGDIGA
>NZ_AP022614|5192721:5295930|5294694_5295930_-|WP_042909891.1|transposase|DBSCAN-SWA
MTIAHDIDLSAVLAERLTTTHPDVLRELLAAFIHALMGAEADAVCGAGYGQRSSERTNSRNGYRHREFDTRAGTLDLAIPKLRQGSYFPDWLLERRKRAERALTTVVATCYLLGVSTRRMDKLVETLGITSLSKSQVSVMAKELDAAVEAFRTRPLDAGPYTFMAADALVLKVREAGRVVNVHALIATGVNAEGYREILGIDVTTAEDGAGWLTFLRSLTARGLSGVRLVTSDAHAGLVAAIGATLPGASWQRCRTHYATNLMAITPKSSWPWVRTLLHSVFDQPDAGSVAAQYDRIIDALADKLPKVADHLEDARADLLAFTAFPKQIWRQIWSNNPQERLNKEIRRRTDVVGIFPDRNALIRLVGAVLAEQHDEWAESRRYLGLDVLSKSRADHTPSTEQEDTPAALTA
>NZ_AP022614|5192721:5295930|5207373_5207973_-|WP_074021707.1|DBSCAN-SWA
MIDAATEIWSESGWAAVTMRGVCSRTSLNDRYFYEDFKTRDELLVAAWDGVRNEMLGEVSATLAERVGQPPLETIRMTISMVVDRITQDPGRAKILLTQHVGSSPLQDRRAVALQEATHLVVAASKPHLRPDADETALRMDTLVAVGGFVELITAWHAGLLDVSQEEIVEHTSRLAETLAERYLVHALSVDDVPGTLPS
>NZ_AP022614|5192721:5295930|5205696_5206566_-|WP_033712834.1|DBSCAN-SWA
MTSESPTRPAKRVLPKARRVRFAMPAGTSRQHFVDGDLVMSHFVSTLSATFPEGEDFFIRSVRQYRDQVSDPDLQEAVKGFIAQEATHRHQHRLLNERLQAMGYPTDGIDRHIKKLVDRLEKRFSPKMRLAVTAALEHYTATFAEIILTSDEAQELIGDTEVRPILLWHALEESEHKAVAFDVFETVGGTERTRVWGMRIATVILFTELVIQTTRSLAGDRAAYNPLRLLRSLRAFRRSPLFSPDAVQRFRSYTRAGFHPDDWDSTEVLERWAKELFDSDGAQRIGSRV
>NZ_AP022614|5192721:5295930|5258891_5260115_+|WP_163670917.1|integrase|DBSCAN-SWA
MIEHGRANALMTDVPDPFRPPQRRHRVIEDANEEQLGKALPDMVIRQLDQHLDLLGPAGRHGSMSAPDLQAMHRTIYQILRDTGRRPGEIVSLKIGCLEVIDGQHNLIYDNHKAARLRRRLPITTDTAEIIAAWQRHRTQLPTAPATRQWLFPSPLLRSRQARGHLTASCVGVAFRTWTRSIPKIDGELLGPDGTPLPFDRSLITPYVLRHSYAQRHADAGVPVDVLKELLDHRSIETTLGYYSVTHKRKQQAIRAVGSLAIDASGNPSSFADPLAYERASVSVPFGNCTEPSNVKAGGGACPIRFQCAGCGFYRPDPSYLPALEEHIHSLQADRETARAMAAADYVVANMSTEIDAFTRVVDTMRRRLAELGPEQRAEVEESSRILRRARAARRLPLIVTSAKDAG
>NZ_AP022614|5192721:5295930|5247724_5248960_-|WP_042909891.1|transposase|DBSCAN-SWA
MTIAHDIDLSAVLAERLTTTHPDVLRELLAAFIHALMGAEADAVCGAGYGQRSSERTNSRNGYRHREFDTRAGTLDLAIPKLRQGSYFPDWLLERRKRAERALTTVVATCYLLGVSTRRMDKLVETLGITSLSKSQVSVMAKELDAAVEAFRTRPLDAGPYTFMAADALVLKVREAGRVVNVHALIATGVNAEGYREILGIDVTTAEDGAGWLTFLRSLTARGLSGVRLVTSDAHAGLVAAIGATLPGASWQRCRTHYATNLMAITPKSSWPWVRTLLHSVFDQPDAGSVAAQYDRIIDALADKLPKVADHLEDARADLLAFTAFPKQIWRQIWSNNPQERLNKEIRRRTDVVGIFPDRNALIRLVGAVLAEQHDEWAESRRYLGLDVLSKSRADHTPSTEQEDTPAALTA
>NZ_AP022614|5192721:5295930|5276779_5278186_-|WP_007168461.1|integrase,transposase|DBSCAN-SWA
MVVGDDEARVRAERARVIGLFRYQLIREAAEPAHSTKERGKIVRELASREHTDPFGRRVRISRQTIDRWIRDWRAGGFDALVPSPRQCTPRTPAEVLELAVALRRENPARTAAAIRRILLTQLGWAPDERTLQRNFHRLGLTAGTGCGSAPVFGRFEAEHPNDLWTGDALHGIAIAARKTYLFAFLDDHSRLLPGYRWGYAEDTVRLAAALRPALASRGVPKAVYVDNGSAYIDTWLLRACAKLGVRLVHSTPHRPEGRGKIERFFRTVREQFLVEITGEPDVAGRHHVADLAELNRLFAAWVETVYHRTVHSETGQTPLARWCASGPVGLPAPEALTEAFLWEEHRRVTKTATVSLHGNSYEVDPALVGRKVELVFDPFDLTRIEVRLAGVPMGLAIPHHIGRHSHPKAKPETPSIPPKPTGVDYARLIETAHQTELARGVNYAALTGADQIPGQLDLLTGEEAQPR
>NZ_AP022614|5192721:5295930|5233383_5234205_-|WP_074021308.1|DBSCAN-SWA
MSFPFGGDGGTHGKYFVNDDIVFSHFVANLSGAFPSGEELFIRSVRRFSDEVTDPTLKKRVAGFIGQESVHGQQHRLLNEKLIDMGYPIAWWDSKKFNDWVKRLEERLPARLPLAVTAAAEHFTAVLAERTLGEEEIQAIPGELQVWNVLNWHAVEELEHKSVAFDVFRTVAGGTERMRRSVMAVMIPTLLLLIAVTLVYSLAHDPDGRRQPLRVIREAYRLYRGPIFRGLIPDLTKYLRPGFHPDDIDTNALLEHWQEELFGTDGELVGYLK
>NZ_AP022614|5192721:5295930|5293521_5293929_-|WP_007168487.1|DBSCAN-SWA
MIYLDTSALVKLIRIEVESDALADWLDERTETRWITSALAEVELPRAIRAVAPNGLSAVPSVLARLDRFEIDQVIRATAAAYPDPALRSLDAIHLATAQIAASTAPLTAMVAYDSRLSDAARALGITIVTPGRNS
>NZ_AP022614|5192721:5295930|5237458_5239135_+|WP_007168424.1|DBSCAN-SWA
MVREIVKGVPSTHGDHYQLNTTNLIRHAARTYPEQEVVYRTTEGDWQRYTYADLYVRVKRAANALRGIGIGPADTVGVLDWNSKRHFELSWAIPGIAAVMLQMNLRLATEDLSYVTDHAEAQWILVDETLLPVAEALAPHVPKVKGWIVMSDKPLTEIDTTLENVFHLEDLMAESDTEIDWRVIDETSAYSACYTSGTTGRPKGVYYSHRGSYLHAMAMAAAINLRREDTAMLITPMFHGQSWGLPHTAMWTAAKVILPGRYLAENTQMLVDVMIAENVTVANGAPAIFQPMLDYIKTLAVKPDFSRTRLLSGATEPAKSLMRDFHELTGADFVQGYGATETTPLITMNMGIKPSLQGTITDDEKWDFKRFQGLPASGIDIRIVDDNGNDLPHDGKSVGEVLMRGPWVIERYHQLDDDDNADRFLDGYWRSGDVGTIYPNGYLKLTDRLKDVVKSGGEWISSIDMENAIVGHPLVKEAAVVGISHPKWQERPLAIVVPVEGGVLTRDDIVGCLQGQFAKWQMPDAVLFVEALPRTSVGKLDKKILRAEHADVYRDAVT
>NZ_AP022614|5192721:5295930|5209951_5211598_+|WP_007168395.1|DBSCAN-SWA
MSDTTSVLIIGAGFAGLGTAIQLLKRGIDDFVILERAGEVGGTWRDNSYPGAACDIPSLLYSYSFEPNPDWSRAYSGSSEILAYIKAMVDKHALARFICFHVNVTGLAFDEDSGTWTVETDGGSSYRSRTVVMASGPLANANFPDIRGLHSYAGHKIHSARWDHDYDMSDKRVAVIGTGASAVQIVPELVKTARSVKVFQRTPGWVLPRPDFPHPSVAKAAFGRLPILQSAARQAWFWAHEVMAVGMVWNTPATTAIAWAAKANLRRQVKDSWMRRQLTPDFRPGCKRMLMTSDYYPALRQNNCKLITWPIATISPIGIRTADGIEHEVDCIVFATGFDVCKAGTPFPITGVDGRKLAEEWSNGAYAYKSVSVSGYPNLFFTFGPNSGPGHNSALVYLEAEIRYIVDAIGIIIEGGIQTFDVKEDRQNSYHAQLQRRLAGTTWNSGCKSWYLTEDGYNGTMYPGFTTQFARQLARVELDDYSMSSQPPPRKKPRRARPELAAESSHGASKGGRQRNDDRVSVDKREGVRFSAQTASPEAASPRMVDRA
>NZ_AP022614|5192721:5295930|5239915_5241064_+|WP_007168426.1|DBSCAN-SWA
MPGLLFPDYVVPWETEDQKLLRKHAAEFFRKEATPNQARWAKQQKVDREFWNKAGAAGLLGLDLPEQYGGGGGSFGHEAVVMQERAYAHDTAFGFSVHSTLASHYIAEYASEEQKKRWIPKMVSGEMVIAVAMTEPGTGSDLQSIRTTAVRDGDEYVINGSKTFISNGSHCDLVVIVAKTESGLSLMVAETEGLAGFQRGRVLEKVGQHGQDTRELAFTDMRVPAANLLGGVEGKGFAQLMEQLPRERLTIGVEAIAMAEAAVVETIRYVKERTAFGKPLLAFQNTKFVLAECKAEVLAGKALIDYCTGRYLDGKLDAATASIAKMWGSDKQVEVTDKCLQLFGGYGYMMEYPIAQMYAAARVQKIYGGTNEIMKVLIARSL
>NZ_AP022614|5192721:5295930|5288105_5288552_-|WP_157137495.1|transposase|DBSCAN-SWA
MLLQTAIEAEVAAFLGRDRYQRTASCADARAGMRNGYCPTTVKTTAGPVTLARPKMRGTTERFASQLFGKGVTKTNALEALVIAGFVRGLSVRDVEATLVEALGEAAAVSKSTVSRICEDINGSVRAVERSPPRRRRARLPVPGRVAL
>NZ_AP022614|5192721:5295930|5264380_5266009_+|WP_007168449.1|DBSCAN-SWA
MQSTMQDVPLSVTSIVKHANSIHADRRVVTPTESGYRAATYGEVGRRVGQLANALHDLGVTGDQRVATFQWSNQEHLEAYCAVPSMGAVLHTLNIRLTAEQLGYIANHADDNIVIVDMSLAPLLARSLPAISSVHTVIAVGEGDPEPLRAAGKAVVSYEDLISTHPTEFDWPELDETSASAMCYTSGTTGNPKGVVYSHRSTYLHSLAVCTGNGLGIAEADRILAIVPMFQANAWGLIYAALMAGAELVLPHRWLQPGALVAIIEDTRPTVAGAVPTIWNDVRHFLGCEPGHDISSLRLVACGGSAVPVSLMRGFERDHGVPIVQAWGMTETSPLATVAKPPTGLDEDQQWALRATQGRPICGVEIRLRNDQDRTLPCNGEAVGEIQARGPWVTGSYFRDDDADKFDQGWLRTGDVGHVDEHGFLTLTDRAKDVIKSGGEWISSVELENLLIAHSGVHEAAVIGVPDEKWQERPLALVVVKPGADITPDELRAFLDGKVATWWIPERWAFVPEIPRTSVGKYDKKVLRACYTAGDYNIVEFV
>NZ_AP022614|5192721:5295930|5199232_5199448_+|WP_019732564.1|DBSCAN-SWA
MAELGIKGISPRRFKTTTVVDPASFPPDLIGQRFDKGRLDAVWSSDIERREALFNRTEVRDHRRRAIAVAR
>NZ_AP022614|5192721:5295930|5192721_5193975_+|WP_101930934.1|transposase|DBSCAN-SWA
MASSRRVKKGPGRRPQSAKRQRFMELRARGWSVRAAAREVGVSRSAATNWTRGYKTYRNGVAVGFVPPLDRLAVRQISTRYLSQDERIEIADLHHSGLRVRTIATRLGRAPSTISRELRRNAPAGRGYQPFDAHRRATARRARHHRRRVDTNDQLGNAVAELLLQRWSPQQISRHLRHRFPDDSSMWLCHESIYQAVYQPNSRFMRPSRLAPHRRSPLRTGRDHRRAHHRQSCRRPRFQQPMLTIHDRSFSAVDRSEAGHWEGDLIIGNNHLSAIGTLVERQTRMLRLVHLPRSDADSLHAALVARMKDLPPTLMRSITWDQGTEMARHLATTDKLGAPVYFCDSRSPWQRGTNENTNGLLRDYFPKGVTLISHPPEQLLAVEHELNHRPRMVLQDRCPADLFAALLVSSDPSVLRR
>NZ_AP022614|5192721:5295930|5223139_5224012_+|WP_007168405.1|DBSCAN-SWA
MAIDPSAVGATTEPMLFEWTDRETLLYALGVGAGTDDLSFTTENSHDITQQVLPTYAVICCPAFGAAGKIGKFNWAMLLHGSQGIRLHAPLPPAGKLSVVSEVADIQDKGEGKNAIIVLRGRGTDPDSGELIAETLTTLVIRGEGGFGGVPGQRPIAPEFPDREPDARIALPTRADQALIYRLSGDRNPLHSDPWFARDMAGFPKPILHGLCTYGVSGRALVAELGKGVAANVTSIAARFTSPVFPGETLTTLIWRTEPGKAVFRTEACGAESANARIVLDDGAVEYAEA
>NZ_AP022614|5192721:5295930|5267209_5267635_+|WP_007168451.1|DBSCAN-SWA
MRRPLEDGYFTMPNGDEQPRLIGSYSPAADKYFFPRRRRCPLTGGPVEDVLLSPTGELYAWTYVESAWMGKSRFGSTGDGHGVGQVDLPEGVRVQSILRGEMGDWEIGMPMQLEVYPLMTDADGTELCSFRFCPTRRGASR
>NZ_AP022614|5192721:5295930|5198288_5199185_+|WP_007168381.1|DBSCAN-SWA
MTVTLERFRTTDGVTLTADCYRHDAARAVVLLLHGGGQNRHAWATTARRLHARGYTVVAYDARGHGDSAWDPTGRYDLGRLASDLLAVREHASTDRPPAVVGASLGGMTVLGTHLLAPADLWGAVVLVDITPRMEFHGARRVVSFMAAHPDGFSTLDDAADVIAEYNRHRTRPKNPDGLRKVLRQRDDGRWIWRWDPAFITSNFQFLQGDPATGAEKFDAISELLVEGARRVQAPTLLVRGVLSDVTSQQSVDEFLKVVPHAQAVDVSGTGHMVAGDDNDAFTAAVAGFLDRTISTSA
>NZ_AP022614|5192721:5295930|5197101_5197746_+|WP_007168379.1|DBSCAN-SWA
MTKKSLRWGTAPPTTRDVARDLLLDAAEACLEGKGLPGTTMEDIARQAGVSRATVYRYFPSRESVVSGVILRAAERYLDRMRRRIAVHRDLGTAILDFVEVTVRAAHREPTIGLLFGSDEELAGVGLAKGTSVALFELVAEFLRPVFAAHWDQLEPGVSVDDAAEWILRTVLSLLSVRGPRHRSPEGLDAFLRRFLLPALLTNTQPCVDATSAE
>NZ_AP022614|5192721:5295930|5206642_5207347_+|WP_057969459.1|DBSCAN-SWA
MRSVRVYRGVSAEQRHQHRRTRLIDAAIELIGTRGVAATTVTAVCAESRVTSRYFYQHFSDRDALLRAVYQQLYATFQDVIVQAIPDAGAPPDVLAYAPIRALVNMIEDDPRLARILFVESATEPLLRELRSQLMAGFADLVLREARLHLDIADSAVGVAHLASTLGVGGLFEVLRRWLDGELDFSTDELVQHCAGFLGSLGTYVLLQNIGEAPVPESGASANALSARGHARRC
>NZ_AP022614|5192721:5295930|5274430_5275648_+|WP_007168458.1|DBSCAN-SWA
MDLSYPPSAEAFRSRVRDFITANVPADFAGIGALDQTRRKEFIREWRKTLADNGLLAVLWPKRYGGAGLTPLHQVVLAEEFARAGVPAGTENDMFGIQLLGNTLVVCGTEDQKNWFLPRILSGDDRWCQGFSEPDAGSDLASLRTRAVLDGDEWVINGSKIWTSVGHLANWIFALCRTDMDAPKHRGISFLLVPMDQPGVEVRPIKNIVGQSMFNEVFFTDARTAADNVVGEVNAGWSVAMTLLGFERGTSVTTDAIRFQAEIDRLFELAKERGKTNDPHIREQLAWCYGRVEIMRCRGYQALTRFLHGEYPGPEAAMTKILWSEFFQRETELAMEILETDVLTLSGTGTNGALATADVGTPNSSLAWVESALAARAATIYAGSSQVQRNIIGEKLLGLPKEPRL
>NZ_AP022614|5192721:5295930|5289177_5289489_+|WP_075362207.1|transposase|DBSCAN-SWA
MAAINGDLANYETVDRLAGIAGLSPVPHDSGRVTGNLKRPRRYDRRLLRACYMAAHNSLRTSPASRAFYDRKRAQGKRHSCRRRLKTDPVSTRWFLGAVATLL
>NZ_AP022614|5192721:5295930|5209031_5209955_+|WP_007168394.1|DBSCAN-SWA
MAFEYGDMLQTIKDRQWALADIDWDAPGAELITDEQRPSLKQFMSDVVWIEHVGARAFAAMAPKAPFDALGEIYRYFHAEEQRHANVELALMHRWGMLEEGETPVPNKNIRLVIEWLDRYAEALPLTVIGAAIPALETALDGALLKFLVDEVSDPVCGEVFAKVNSDESRHLAVGFQVLNDLGASPMRIHAIQTVGALIDPRVLTGALLYIPLLTRMLINLNAWGLSEERLYNAVTRYSNVGDRSEHTRRVPPYHILKAHMSATIKHSQPLHFISQRLGRVIDHFPTQVLGKTPSWTDELTYEPVAR
>NZ_AP022614|5192721:5295930|5293159_5293501_-|WP_007168486.1|DBSCAN-SWA
MSARFYDETVFQAWQRGVEIAGPRWFADGQTSPDSATSKWDLSPRVDEIRSAIGWLSSGEAMFLAAMVSFYNSEPGGELLRSLGANGLSDIAASLDESRRQVIADLPLAYAGW
>NZ_AP022614|5192721:5295930|5266061_5267003_+|WP_007168450.1|DBSCAN-SWA
MATTRYHSLGAGGLNWESVPLRLFAGGIAKLWDPANIDFSRDSADWEALSDRERVYVTRLCAGFIAGEEAVTQDIQPFMAAMRAEGRLGDEMYLTQFAFEEAKHTQAFRLWLDAVGVRDDLHSFLDQTPAYRQLFDEELHESLNTLYVDPSPAAQVRASVTYNHIIEGMLALTGYYAWHKICVEHGILPGMQQLIRHIGDDERRHMAWGTFTCRRHVAADDTNWTVFETRMNELIPLGQRLIDEGSALYGDDIPFNLSIDEMRTYATDKGMRRFSTISSARGRPPEEIDLDYSPLQLEDTFADEDARVLAGSA
>NZ_AP022614|5192721:5295930|5283399_5284482_+|WP_040622630.1|DBSCAN-SWA
MLRSRSGQWGVGNVGTVALRHFVGNPAYEVVGVLCNRPEKVGKDAGELVGAAPIGVLATTDKEAIEALDADCVFYAPLWSDPEEVCRLLRGGKNVVASGGAWWYRTEHSKADIDKIDAACHEGGTSFHAGGINPGFAGDLLVLTLARIVSRIDAIHIYEVVNFGKDTLKYLHEMGMGSDPEEFLAGPNLLGNAWPLFAQSMAMVADGFGKTVDKYTTDVELGTATRDIRYEGGPTSDMPGFKGVIKKGTVASQHHKWTTWVDNKTFITFHEMYTMDEYNAIEPQPDWGGHYHYRIVIEGDEPTELILQAPPDAQGNYPKPGYTWTAMGPANAIPAVCDAPPGFLTHKELGLVPLRGLVRL
>NZ_AP022614|5192721:5295930|5202850_5204152_+|WP_007168386.1|DBSCAN-SWA
MIASTTSALKTSAERRSARPYDSADLSSTAFWAGTAADREKTYAELRKRAPISWHPRVEHTMIDDGNDRGFWAVVTHPLLVEATRRHDDFLSGQGIVMESIPQELLDTAQGFIAMDPPRHTKIRRLLASAFTPKQMRLIHHQIEANAKRVVDDLAPQGKADFVDECAALLPMHNIFDMMGVPDSMRRDIAWESRYAGGWSDPEVMGDDPVIPRLFQAMGFLGDGAREIIAARRRQPEDDLMTNLVQAEVDGEKLTEDEIVSFFILLTIAGNDTTRQSTSHAMKALTDFPDQRAWLMEDFDGRIKGAVEEFVRWATPIMTFRRTAARDCDLGGQQITEGDKVVLFYSSANWDTTVFTNPEKFDLSRDPNPHVSFGGGGIHHCLGNQLARQQLAALFRELLHRLPDIEVCGPPSYTVSTFFHGVNHLPVRFTPTT
>NZ_AP022614|5192721:5295930|5204487_5205504_+|WP_033717470.1|DBSCAN-SWA
MSTFGLSVLAPDLAAMKVTATAADQAGFDAVWASEFYTRSGSISMAAMATSTDRCRIGSSILYGVGRSPLVLATEARDLDELSGGRIVLGIGNGTKRMMSNWHSVADTSAPALRVEELVPLIRRIWNLHEGPVRHEGRFYQMNLIPSGPVDPPARDIPIITAAVRPRMCEAAGRVADGLAGHPLFTTAYVEEVVRPAVAKGAARTGRDPDDVEIVSMVMCSIHDDPEIARREVAQQIAFYASVRTYQPLLDFCGFAKQGAVIREAFARGDFAAMFDAVTDDMIDVMGVAGTASEVRAGLRRYEGVLDHIMLYPPSVGIAPERVGQNLGEMIKHCAPGQ
>NZ_AP022614|5192721:5295930|5214338_5215796_+|WP_075630242.1|DBSCAN-SWA
MVNPLHAPVDKARERLSSVILIPAPQRVDDGLRRWSRRWPVRELAAPPAGSGLRPVLGDAGLPLVGHTLDYIRFGSDLGRERYERFGSVSWMGAFGTKMAVIAGPQATQEALTTNAKAFSQDGWAFLIDAFFHRGLMLMSFDEHLMHRRIMQEAFTRPRLAGYVTQVTPCVRATLPTWPTGPSVRMYPLLKNLTLDIATDVFMGGRGKDSSDAINQAFVATVRAASSLVRAPLPGTRYRAGIRGRRVLEEYFARHLPAARAGNSNDLFAALCHASTEDGQRFSDSDVINHMIFLMMAAHDTSTITTTAVTYYLAKHPEWQDRVRAESDALGDRSPEIDDLEALRSLDLVIKESMRLVAPVPLVMRKTVQDTAIDGHYIPRDTLVAITPAVNHFVREVWHDPDRFDPLRFDDPRREDQAHRFAWLPFGGGAHKCIGMHFGTLEVKAILHQMLRTFTFGLDTDYRIRWDNTSLPIPVDGLPITLRRR
>NZ_AP022614|5192721:5295930|5218146_5219289_+|WP_033712837.1|DBSCAN-SWA
MTVASPWLSPELEALRDLAAKFVATEIAPHSERFAEQHHVDRAVWERAGELGLLCMSMPVEYGGGGGTFAHEAVLLEEQARIGDSSWGAGLHSGIVAHYILHYAREDLKRQWLPKMASGELIGAIAMTEAGTGSDLQSVKTRAVLDGDEYVITGSKTFITNGQQADLVVVVAKTDHTQGASGISLIVVEADRPGFRRGRVLSKIGQRGQDTSELFFDGVRVPKTHLLGDTEGQGFFQLMTQLPQERLIVAVGAVAAMELALHQTIEYTRQREAFGRTIFGFQNTKFTLAEAATETRIARVFLDHCICLHLDGKLDVQTVAMAKWWTTERAMKVLDDCLQLHGGYGYMTEYPISRLWVDQRVQKIYAGSNEIMKEIISRSL
>NZ_AP022614|5192721:5295930|5236273_5237449_+|WP_019732177.1|DBSCAN-SWA
MNAREAVIVGAVRTPVGKRGGALSRWHPADLLGHTLRNLVERSAIDAKDIDDVIVGCAMQHEHQSGNIGRHAVLAAGLPESVPAVTIDRQCGSGQQAVNFAAFGVTAGIYELAIGCGVESMSQVPMPASFMPGAPLGPQYSPVELARYDDNLVAQGAASELLNSKFGISREELDEFSIRSHERAFAATRAKKFRAQLVPITVDPLDPSAAPVSADEGIREQLDPAKIASLEPVFAADGRTTAANSSQISDGAAALLIAERGYAERSGLVSRARFLAMTVAAADPVLQFTAVLDATHRALERANLSVSDIDLFEVNEAFAGVPLMVQREFGIPDDKLNVNGGSVAIGHPLGSTGARMLTDLLCELERTGQRYGLQTICEAGGTANTTIIERI
>NZ_AP022614|5192721:5295930|5271634_5272756_+|WP_050790029.1|DBSCAN-SWA
MDFMLSPEQDDFRQTIQQFVTELSPLAKVRQAVTTAPGYDIDLWSRMSRELGLPSLLVPEEYGGAAATMIEAAVAIEELGRGIVPCPLFATVALGVAPILIAASQEQKRELLPEIAAGARTVTTAINEPGCVDGFGAVAMRAATNGDAVTLSGTKIHVIDGHSADTLLVLALPPGDSAEPALYLVDGNAVGLTRTRVETLDITRPLATLTFDAVSAVPLAGAHGVAPIRRALDVAKTLLAAEMVGGTEGAMTMSVEYAKVRHQFNRPIGSFQAIKHRCAEMAIELDSARAVTLYAAHLAAEESADLAKAAPIAVATAAAGFDFTASWNVQIHGGIGFTWEHDAHLYYRRAKADRVLLGSVREQWLEVADRIGL
>NZ_AP022614|5192721:5295930|5276174_5276672_-|WP_074021181.1|DBSCAN-SWA
MGWCIAERRIGVITGEVGVGKTYLATALGHMVIRRRNSVLFARSDKLFTRLRAARLDNTVDAEIRRLTTIDVLIIDDFALRPLGATETSDFYEIIVERHRAKTTIVTSNREPSEWLTMTADTLLAQSAIDRLTATAHTLVIEGPSYRQRTRPSQLDPDHDDELPQ
>NZ_AP022614|5192721:5295930|5219675_5220002_-|WP_033711234.1|DBSCAN-SWA
MHSELRRAIKPIGYGAGRDGQRRRLYDEPMTPLDRLLAAGVLSPAQESELLAYRDTLNPAAIARQIADLQAALLRLAKNKTEHLYLAAIPTALPEVRSGIRIQNKTAS
>NZ_AP022614|5192721:5295930|5215792_5216449_+|WP_085271655.1|DBSCAN-SWA
MKTEFARFLAATEFLDWKHDAVQQFTESATRNATDSVDKACRIFTAVRDSIWYDPYSVSDDPRQYRASAVAVAERAYCVPKAVLLTAACRAAGIPARLGFADVRNHLQTASLRERMGGSDVFVYHGYSQILLNGRWVKATPAFNRELCARFRVAPIEFDGQRDAMLHAYTGDSSQHLEYLHDRGVFDDLPLTEIIDALRDNYGELIYEPPPVPDSFTN
>NZ_AP022614|5192721:5295930|5257289_5257643_+|WP_163670913.1|integrase|DBSCAN-SWA
MLSTYADYQFERTEILGGDDCDMVFVNLYHEPLGVPMTYRAAKRFFERLATDCGFAVRPHMFRHTAATNWVRAGVDLDVVQRLLGHAALASTAVYLHARDEDKRRAVEAVAAGERFR
>NZ_AP022614|5192721:5295930|5204163_5204355_+|WP_074021704.1|DBSCAN-SWA
MKITVDRDRCSSIGMCEGLAPDFFEVSNDGKLHILNPGPPECHRALIEDAVASCPTGALALHD
>NZ_AP022614|5192721:5295930|5199977_5201426_+|WP_007168383.1|DBSCAN-SWA
MNTSALWPDPDTAELRVRRMQRKLHHWAVDESDRCFDDLYNLVYDPAFLTLAWERVRTNKGARSAGADGTAPRSVGAAEAVGLLQRLREELKERIFRPDPVREVMIPKANGKLRRLGIATVADRVVQASLKLVLEPIFEADFHPCAYGFRPGRRAQDAIAEIHHLASGSRAYHWVFEGDITACFDEISHSALMGRVRRRVGDKRVLALVKSFLKAGILSKDLGYRDTITGTPQGGILSPLLSNVALSVLDEHFAAKWKALGPEWTRAKHRRAGVPTMKIVRYADDFCVMVHGTRADAEALWDEIAAVLAPMGLRLSVEKSRICHVDEGFEFLGFRIQRQIKRGTTKHYVYTWPSKKALMSITDKVRNLTRRHKHRTLADLLRQLNPVLRGWCNYFQHGVSKRTFDYLDHFTWWRVVTWMRKRHHGLAWGVFHRRFLPNWQIREGKTAMFRPQKVEVTRYRYRGTKIITPWTARPTDITAPVA
>NZ_AP022614|5192721:5295930|5252884_5254051_-|WP_007168437.1|integrase|DBSCAN-SWA
MRVFPVSLPSGQRYWTVLDEDLQVVDVADAYLRHLRFGHDAAESTTKAYAHSIALFLRWCARSGRSWQAGVEGFALFMTWLAHARSSVDDAASVVVAGPGAAAVRGPSRINGVLTAVRGMVVHAVATGHGAAGLVSMLYEVADDRDLPAEARGEDGRMAWRMRARHRLREPETTIDRASDEQIVALLRACRSARDRLIVLLMARGGLRRGEVCGLRRSDVHLLVDSRRLGCDVERAHLHVVRRDDNPNQAWAKSRRERVVPLDFLVVQLFDVYEFERMRVTGAADSDFVFVNLFRGRIGAPMRPDAIGELMAAASRRAGLDVAVRPHQLRHAFGSNVVDAGAGIDVVADLMGHAAVSSSQVYLHPDSSRLRAAVDAVPSPREQAQVTR
>NZ_AP022614|5192721:5295930|5208176_5209013_+|WP_007168393.1|DBSCAN-SWA
MRLLPFGNPPRRSDRADAVITGAGSGIGRAFAVELARRGGRVVCADIDGIRAKETADLISKLGGHGIGVVCDVSDEHQVRDLADSAEKWFGGAPGLVINNAGIGAGGNVVGATSTSDWSATLSVNLWGVIHGCEVFVPRLRERGFGGLINVASAASFGAAPRMAAYNVSKAGVLALSETLAAELSGTGVTVTVLCPTFVKTNIVDNPRIEESAATLAANLMKWTGVSPESVARTTLDAHDRGQLYVLPQLDAKILWQLKRTMPGTFTHAMGLIQRITR
>NZ_AP022614|5192721:5295930|5242835_5244188_+|WP_046184758.1|transposase|DBSCAN-SWA
MPSPGRPSVAWRQDRVRFWAGIAAGAMTEDAATEAGVSSPVGFRWFRHAGGVNPRLPETVSGCYLSSNEREDIALWRAHGAGVREIARRLRRAPSTISRELRRNASTRTYRLDYKASVAQWHAERRARRPKTAKLVGNDRLRQYVQDKLSGVVRGAYGQIMAGPAATPWKGRNKPHRGDRAWVTAWSPEQIAHRIKLDFPDDESMRISHEAIYQALYVQSRGALKRDLITCLRRGRALRVPRARSRQKAWAHVTPETLISARPPEVADRAVPGHWEGDLLIGLQRSAIGTLVERSSRFTMLIHLPREAGYGLIPRTKNGPALAGYGALTMANALAQTITSLPEELRRSLTWDRGKELSAHAQFSIASGVKVYFADPKSPWQRGTNENTNGLLRQCFPKGTDLSRWNADDIAAIAHTLNTRPRKTLGWRTPAEAFNEHLHSLQQAGVATTD
>NZ_AP022614|5192721:5295930|5278232_5278379_-|WP_007168462.1|DBSCAN-SWA
MIERRFALPEVSLAEVAVAVSGGRLLASGWPGEWVQHESTLPPRQMRP
>NZ_AP022614|5192721:5295930|5216481_5218098_+|WP_085981616.1|DBSCAN-SWA
MQDIPLTVASIVRHATSIHADSQVVTPTGSGYRTTTYGALKRRISQLANALRSLGITDDQRVATFQWSNQEHLEAYCAVPSMGAVLHTLNLRLTAEQLGYISDHADDKVIIADVSVAPLLAKALPTMSSVHTVIAAGDGDLEPLLASGKNVLRYEDLLADQDGEFDWPELDERSAAAMCYTSGTTGNPKGVVYSHRSTYLHSLTGCTPNVLSIGEEDRVLAIVPMFHANAWGLIYSALMCGADLVLPDRYLQAAPLVAIIEDTQPTVAGAVPTIWNDVQHFLESEPEHDISSLRLVACGGSAVPRSLMEHFESEFGVPILQAWGMTETSPLATVARAPKGTNGERQWELRACQGRPVCGVEIRLRGDDGRTLPWDGRSIGEIQARGPWVTGSYFGDNDSDKLDEGWLRTGDVGRIDQHGYLTLTDRVKDVIKSGGEWISSVDLENALVAHPAVHEAVVIGVPDEKWQERPLALIVTKTETSLDINELRVFLDGAVAKWWIPERWAFIAEVPRTSVGKYDKKLLRARHGAGEYQVVYCG
>NZ_AP022614|5192721:5295930|5267652_5268777_+|WP_101930904.1|DBSCAN-SWA
MIGVGMAPFGQPDANAADLGFGAGVNALGDAGIGFDEVGYLYNGYIGAGLLTGVTLAKDLGLTGIPITHVENASATGSCAFHEAVQVVAGGSVDIAMALGFDDLNRATRAIGGSKPGIGQVILPAAFFAMWATRRMHEVGTTVETFAAIAAKNWNHARLNPYAQRRADHEVTVEEILASRMISYPHTSKMACAAGSGAAAAIVASREAAERVAGSRPLVKVVASQQQSEQFVDGHIFMGAVVGPGELTAATAKAAYDEAGVGPADLDLAHVHDAFPIEELMYYELLGVCAAGEGDKLVSEGATSLGGRIPFSTDGGLIGRGHPGGPTGLAQIWDVTRQLRGEAGPLQVEGARTGLAHMMGAGSVCVIHILQAGR
>NZ_AP022614|5192721:5295930|5244815_5245142_+|WP_007168431.1|DBSCAN-SWA
MKWNLRLTAANRGIWKASELQRMLAERGLVISAGKMSGLWSGNPNAIKLHDLDVFCAVLDCAIDELLIPEPETVAAPTPKGSEEAAAAAGEARPVTPRARTGRSLPPR
>NZ_AP022614|5192721:5295930|5250398_5251493_-|WP_101930905.1|integrase|DBSCAN-SWA
MCAHLDALEPVEVRVATQIGIDTGRRPEDILALPLNCLHRDKDGSAVLVYDNAKANRLGRRVPIGEATAKVIAAQQDRVRAMFPHTPPAELTLLPTPRRNPEGRKPISIDTLDNRHREWISTLPVLRTRDGVEVDKTKVTPYAYRHCYAQRHADAGVPIDVLAELLDHRSYSMTRRYYRIGEDRRRDAVDTVTALSFDRHGNRIWRDARMLLESERARHAVGEVAVPYGTCTEPTNVKAGGGACPVRFRCVGCDHFRTNIAFLPDLQAYLDDLLRTRERLAATIDGVDDWARADATPTDEEITRIRRLINRIKADVADLNETEQARIDDAIAIVRRHRAAHTVPLGMPSLTPPAPTTIASEATA
>NZ_AP022614|5192721:5295930|5224439_5224832_+|WP_007168407.1|DBSCAN-SWA
MAAIYLDSSAIVKLAVREPESDALRRYLRTRLPRVSSALARTEVMRALLHKGESARRAGRRALASLDLLRIDNRLLDLAGGLLPIELRTLDAIHLATAQRLGMDLGRLCTYDDRMRDAAEALGMAVIAPS
>NZ_AP022614|5192721:5295930|5260207_5260702_+|WP_085271075.1|DBSCAN-SWA
MQTLETTGAPITFTAVAKAAGVSTWLVYADGIREHIDAARHRQSNHHRRTDTPAASSTHPATPDSLRADLAIAREQIKTLRTERDKLQQRLRLQLGAELEAPDRAHLTARVVDLETINRQLVAERDARAIEAQTAKGRVTELEDELSAARESLRRVIKAQNRAP
>NZ_AP022614|5192721:5295930|5269767_5271387_+|WP_007168454.1|DBSCAN-SWA
MAVIDLLRQAVEDRPDKTAVIAEDGAATFRELDAASSRVAQQLHAAGVSRGHKVAMLLANDQAMHFNAVYFGIHKLGAVPVPLNTRWAAPEKLFVLEHSDAVAVITGLAHREVLVALAEGESVEIGGRPGSFQLEHFFVTGSEALDGFTPLGDVVGAGSADVPLLEPSLSADDPADLLYTSGTTGMPRGVLVPEGNLADEPGQASLGQLLGAMFGESLLHAVPLFGFTGCHGLMLLSIRAGVTQIVLPRFDPEQLLAAIERYRATSIMGVPTMLNLAMKHPTVGDHDYSSLQLVFFGAAPIQPDTVRKMRQVWPGAKMLNAYSLTEAGAGAACILGPDPDDILARPGSVGRPVGCEVVVVDDYDNPLPPGKVGEICFKSKIARRSYYKGEQPTAELWSGGLLHTGDVGYVADDGYVYLTERKKDMILRGGYNIFAIEVERVLLEMPEVLEAAVIAVPHSDLGEDLLAVIAPKPGFSGGEGELTAERINQFCRQHLADYKCPRHMVVVDELPKNAMAKVMKNELRQRFRDHLFDQGAENK
>NZ_AP022614|5192721:5295930|5280508_5280835_-|WP_007168467.1|DBSCAN-SWA
MTYTIAEPCVDIKDKACIEECPVDCIYEGARMLYIHPDECVDCGACEPVCPVEAIYYEDDVPEQWSQYTQINADFFVELGSPGGAAKVGMTENDPQVVKDLPPQGEGD
>NZ_AP022614|5192721:5295930|5202172_5202763_+|WP_007168385.1|DBSCAN-SWA
MREQVLRAARTLTIEKGWDRVRMGEVAELVGVSRPTLYKEFTDKQGLGDALVVAEGERFLNGIHAVLAQHAGDVGGGITAAVSYTLKEAEASPLLKAVLTSNRPTDRTVAESTGMLPLLPTSASLLELSSAALVTWFNEHFSGLDANDVNDVADALVRLTVSHVVLPTADAETTGERISRIALRYLGVHSSAGEAR
>NZ_AP022614|5192721:5295930|5213192_5214161_+|WP_007168397.1|DBSCAN-SWA
MTTLYSEQHPSTASYLIATSARGILRPLTQALPSNQYGLAVMDRVLRAALIASRPRRGLRVEQVDTVFAGDRVRGDWIVAPDVDPDGPPILYIHGGAFSMCSPQTHRGLLGELSAASLRPVFAVRYRLAPRYPYPAAADDALRAYRWLTGSEESASNRTVAIAGDSAGGQLAVATSLGALAHRSPPPDGMLLMSPVVDLTCQLAMARETRRRDPFASARSATRALSLYVGDAHPTDPRVNVLAADLTGLPPTLIQVGGREMLLDDSRQLAERMRAAGASVRLQVFRGQIHVFQALFRLLPEARHALHLSGAFLTDRAEDTFP
>NZ_AP022614|5192721:5295930|5234587_5235331_-|WP_007168420.1|DBSCAN-SWA
MGPFADPRAGADDLTAKARIRNAAMDLFAEFGEDRTSMRNIASRAGVTVGLVVHHFKTKDGIRRAVEQLVVDYFAQTIAQVPVDGTPRQVATARDVAVKEMLESNPAVVNYLRRALLDPAGSKGQLLQRLTELTRTELIKARDAGIANAERSGSTQIIDIMVRQLGQLFLQPMIDTMWDQVSRPDESDDDKPTLHVAVRSSGPAPSARHRNTSACAAGEVVWRPAGPLPAAGPRPSTGAEHCHATSR

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_101930934.1|5192721_5193975_+|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	6.1e-29	31.1
WP_042909891.1|5194406_5195642_+|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	1.0e-84	45.2
WP_007168379.1|5197101_5197746_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_007168380.1|5197795_5198236_+	PaaI family thioesterase	NA	NA	NA	NA
WP_007168381.1|5198288_5199185_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_019732564.1|5199232_5199448_+	hypothetical protein	NA	NA	NA	NA
WP_007168383.1|5199977_5201426_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	4.4e-55	35.6
WP_007168385.1|5202172_5202763_+	TetR family transcriptional regulator	NA	NA	NA	NA
WP_007168386.1|5202850_5204152_+	cytochrome P450	NA	NA	NA	NA
WP_074021704.1|5204163_5204355_+	ferredoxin	NA	NA	NA	NA
WP_033717470.1|5204487_5205504_+	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_033712834.1|5205696_5206566_-	metal-dependent hydrolase	NA	NA	NA	NA
WP_057969459.1|5206642_5207347_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_074021707.1|5207373_5207973_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_007168393.1|5208176_5209013_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_007168394.1|5209031_5209955_+	hypothetical protein	NA	NA	NA	NA
WP_007168395.1|5209951_5211598_+	NAD(P)-binding domain-containing protein	NA	NA	NA	NA
WP_007168396.1|5211672_5213196_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_007168397.1|5213192_5214161_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_075630242.1|5214338_5215796_+	cytochrome P450	NA	NA	NA	NA
WP_085271655.1|5215792_5216449_+	transglutaminase domain-containing protein	NA	NA	NA	NA
WP_085981616.1|5216481_5218098_+	long-chain fatty acid--CoA ligase	A0A2H4PQU7	Staphylococcus_phage	1.6e-26	24.5
5217972:5217995	attL	NA	NA	NA	NA
WP_033712837.1|5218146_5219289_+	acyl-CoA dehydrogenase family protein	NA	NA	NA	NA
5217972:5217995	attL	NA	NA	NA	NA
WP_033711234.1|5219675_5220002_-	hypothetical protein	NA	NA	NA	NA
WP_007168405.1|5223139_5224012_+	MaoC family dehydratase N-terminal domain-containing protein	NA	NA	NA	NA
WP_007168406.1|5224164_5224440_+	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
WP_007168407.1|5224439_5224832_+	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_007168413.1|5229897_5230851_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_007168414.1|5230847_5232425_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_065517439.1|5232446_5232992_-	metal-dependent hydrolase	NA	NA	NA	NA
WP_080576328.1|5232978_5233353_-	metal-dependent hydrolase	NA	NA	NA	NA
WP_074021308.1|5233383_5234205_-	metal-dependent hydrolase	NA	NA	NA	NA
WP_007168420.1|5234587_5235331_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_065517438.1|5235428_5236277_+	CoA transferase	NA	NA	NA	NA
WP_019732177.1|5236273_5237449_+	thiolase family protein	NA	NA	NA	NA
WP_007168424.1|5237458_5239135_+	long-chain-fatty-acid--CoA ligase	NA	NA	NA	NA
WP_007168425.1|5239131_5239908_+	enoyl-CoA hydratase/isomerase family protein	NA	NA	NA	NA
WP_007168426.1|5239915_5241064_+	acyl-CoA dehydrogenase family protein	NA	NA	NA	NA
WP_007168427.1|5241089_5241848_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_046184758.1|5242835_5244188_+|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	6.3e-32	34.6
WP_007168431.1|5244815_5245142_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_042909891.1|5247724_5248960_-|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	1.0e-84	45.2
WP_007168435.1|5249811_5250330_-	hypothetical protein	NA	NA	NA	NA
WP_101930905.1|5250398_5251493_-|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_007168437.1|5252884_5254051_-|integrase	tyrosine-type recombinase/integrase	A0A2K9VF00	Mycobacterium_phage	1.6e-07	29.1
WP_163670911.1|5256580_5257381_+|integrase	site-specific integrase	NA	NA	NA	NA
WP_163670913.1|5257289_5257643_+|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_163670915.1|5258232_5258895_+	hypothetical protein	NA	NA	NA	NA
WP_163670917.1|5258891_5260115_+|integrase	tyrosine-type recombinase/integrase	A0A1P8DJP1	Virus_Rctr41k	4.1e-06	33.3
WP_085271075.1|5260207_5260702_+	hypothetical protein	NA	NA	NA	NA
WP_007168443.1|5261308_5261740_+	hypothetical protein	NA	NA	NA	NA
WP_007168449.1|5264380_5266009_+	long-chain fatty acid--CoA ligase	A0A2H4PQU7	Staphylococcus_phage	6.7e-28	25.3
5265883:5265906	attR	NA	NA	NA	NA
WP_007168450.1|5266061_5267003_+	R2-like ligand-binding oxidase	NA	NA	NA	NA
5265883:5265906	attR	NA	NA	NA	NA
WP_007168451.1|5267209_5267635_+	OB-fold domain-containing protein	NA	NA	NA	NA
WP_101930904.1|5267652_5268777_+	thiolase family protein	NA	NA	NA	NA
WP_007168453.1|5268843_5269737_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_007168454.1|5269767_5271387_+	acyl--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	1.1e-30	28.1
WP_050790029.1|5271634_5272756_+	acyl-CoA/acyl-ACP dehydrogenase	NA	NA	NA	NA
WP_007168458.1|5274430_5275648_+	acyl-CoA dehydrogenase family protein	NA	NA	NA	NA
WP_074021181.1|5276174_5276672_-	ATP-binding protein	NA	NA	NA	NA
WP_007168461.1|5276779_5278186_-|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_007168462.1|5278232_5278379_-	hypothetical protein	NA	NA	NA	NA
WP_007168467.1|5280508_5280835_-	ferredoxin family protein	NA	NA	NA	NA
WP_007168468.1|5281183_5281462_+|transposase	transposase	NA	NA	NA	NA
WP_154074411.1|5281458_5281614_+	hypothetical protein	NA	NA	NA	NA
WP_007168470.1|5281689_5282139_+|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_040622630.1|5283399_5284482_+	dihydrodipicolinate reductase	NA	NA	NA	NA
WP_136244823.1|5286907_5287189_-	hypothetical protein	NA	NA	NA	NA
WP_167310147.1|5287318_5287507_-	hypothetical protein	NA	NA	NA	NA
WP_157137495.1|5288105_5288552_-|transposase	transposase	A0A220NQR7	Corynebacterium_phage	2.9e-10	40.8
WP_075362207.1|5289177_5289489_+|transposase	transposase	NA	NA	NA	NA
WP_085272092.1|5289522_5290758_+|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	1.0e-28	31.1
WP_007168486.1|5293159_5293501_-	hypothetical protein	NA	NA	NA	NA
WP_007168487.1|5293521_5293929_-	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_033711258.1|5293932_5294205_-	type II toxin-antitoxin system prevent-host-death family antitoxin	NA	NA	NA	NA
WP_042909891.1|5294694_5295930_-|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	1.0e-84	45.2
5294638:5296055	attR	NA	NA	NA	NA