CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_AP022587	Mycobacterium stomatepiae strain JCM 17783	3 crisprs	cas4,WYL,csa3,casR,cas14i,c2c9_V-U4,DinG,DEDDh,cas3	0	1	1	0

1. NZ_AP022587

CRISPR-Cas detection and classification

Crispr_ID: NZ_AP022587_1

• CRISPR_ID: NZ_AP022587_1
• CRISPR_location: 2130968-2131051
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_AP022587_1

Consensus_repeat	Method
CAACATGTCTTGCCACGTCTTGGGCTT	CRISPRCasFinder

spacers of NZ_AP022587_1

>1.1|2130995|30|NZ_AP022587|CRISPRCasFinder
TCCCCCGGGCGGAGCCTCGCCAGGCGGAAC

CRISPR arrays and Neighbor proteins around NZ_AP022587_1

CRISPR arrays

The CRISPR arrays of NZ_AP022587_1

>merge|NZ_AP022587|1|2130968-2131051|CRISPRCasFinder
CAACATGTCTTGCCACGTCTTGGGCTTTCCCCCGGGCGGAGCCTCGCCAGGCGGAACCAACATGTCTTGCCACGTCTTCGGCTT

>NZ_AP022587|1|1|2130968-2131051|CRISPRCasFinder
CAACATGTCTTGCCACGTCTTGGGCTT	TCCCCCGGGCGGAGCCTCGCCAGGCGGAAC
CAACATGTCTTGCCACGTCTTCGGCTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP022587.1|WP_163789899.1|2124703_2126479_+|NAD-binding-protein	unknown	unknown	gnl|CDD|367001
NZ_AP022587.1|WP_163789901.1|2127573_2128404_-|TIGR03619-family-F420-dependent-LLM-class-oxidoreductase	unknown	unknown	gnl|CDD|274680
NZ_AP022587.1|WP_163794642.1|2131619_2131916_-|RNA-2'-phosphotransferase	unknown	unknown	unknown
NZ_AP022587.1|WP_163789902.1|2128860_2129277_-|hypothetical-protein	unknown	unknown	unknown
NZ_AP022587.1|WP_163789900.1|2126676_2127498_-|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|369777
NZ_AP022587.1|WP_163789910.1|2137989_2139255_-|IS30-family-transposase	unknown	unknown	gnl|CDD|225382
NZ_AP022587.1|WP_163789896.1|2119657_2120293_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl|CDD|153251
NZ_AP022587.1|WP_163789907.1|2135346_2136765_-|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|237218
NZ_AP022587.1|WP_163789906.1|2135009_2135324_+|hypothetical-protein	unknown	unknown	gnl|CDD|227505
NZ_AP022587.1|WP_163794641.1|2129301_2129655_-|hypothetical-protein	unknown	unknown	unknown
NZ_AP022587.1|WP_163789908.1|2136849_2137317_-|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl|CDD|369560
NZ_AP022587.1|WP_170313087.1|2133722_2134187_-|CAP-domain-containing-protein	unknown	unknown	gnl|CDD|349398
NZ_AP022587.1|WP_163789911.1|2139271_2139604_+|hypothetical-protein	unknown	unknown	unknown
NZ_AP022587.1|WP_163789897.1|2120294_2121203_+|phosphatidate-cytidylyltransferase	unknown	unknown	gnl|CDD|366491
NZ_AP022587.1|WP_163789895.1|2118446_2118779_-|DUF732-domain-containing-protein	unknown	unknown	gnl|CDD|368380
NZ_AP022587.1|WP_170313037.1|2118929_2119661_+|CDP-alcohol-phosphatidyltransferase-family-protein	unknown	unknown	gnl|CDD|223632
NZ_AP022587.1|WP_163789898.1|2121199_2122930_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|224054
NZ_AP022587.1|WP_163789905.1|2133170_2133710_+|restriction-endonuclease	unknown	unknown	gnl|CDD|377369
NZ_AP022587.1|WP_163789904.1|2132136_2132946_+|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|223377
NZ_AP022587.1|WP_163789909.1|2137412_2138042_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP022587.1|WP_163789899.1|2124703_2126479_+|NAD-binding-protein	gnl|CDD|367001	pfam02254, TrkA_N, TrkA-N domain. This domain is found in a wide variety of proteins. These protein include potassium channels, phosphoesterases, and various other transporters. This domain binds to NAD.	4.77165e-14
NZ_AP022587.1|WP_163789901.1|2127573_2128404_-|TIGR03619-family-F420-dependent-LLM-class-oxidoreductase	gnl|CDD|274680	TIGR03619, F420_Rv2161c, probable F420-dependent oxidoreductase, Rv2161c family. Coenzyme F420 has a limited phylogenetic distribution, including methanogenic archaea, Mycobacterium tuberculosis and related species, Colwellia psychrerythraea 34H, Rhodopseudomonas palustris HaA2, and others. Partial phylogenetic profiling identifies protein subfamilies, within the larger family called luciferase-like monooxygenanases (pfam00296), that appear only in F420-positive genomes and are likely to be F420-dependent. This model describes a domain found in a distinctive subset of bacterial luciferase homologs, found only in F420-biosynthesizing members of the Actinobacteria. [Unknown function, Enzymes of unknown specificity].	5.82244e-92
NZ_AP022587.1|WP_163789900.1|2126676_2127498_-|methyltransferase-domain-containing-protein	gnl|CDD|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	1.65706e-24
NZ_AP022587.1|WP_163789910.1|2137989_2139255_-|IS30-family-transposase	gnl|CDD|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	5.28888e-91
NZ_AP022587.1|WP_163789896.1|2119657_2120293_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase	gnl|CDD|153251	cd07989, LPLAT_AGPAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.	4.77145e-42
NZ_AP022587.1|WP_163789907.1|2135346_2136765_-|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|237218	PRK12825, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional.	4.01885e-13
NZ_AP022587.1|WP_163789906.1|2135009_2135324_+|hypothetical-protein	gnl|CDD|227505	COG5178, PRP8, U5 snRNP spliceosome subunit [RNA processing and modification].	0.00754126
NZ_AP022587.1|WP_163789904.1|2132136_2132946_+|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|223377	COG0300, DltE, Short-chain dehydrogenases of various substrate specificities [General function prediction only].	1.46658e-39
NZ_AP022587.1|WP_163789897.1|2120294_2121203_+|phosphatidate-cytidylyltransferase	gnl|CDD|366491	pfam01148, CTP_transf_1, Cytidylyltransferase family. The members of this family are integral membrane protein cytidylyltransferases. The family includes phosphatidate cytidylyltransferase EC:2.7.7.41 as well as Sec59 from yeast. Sec59 is a dolichol kinase EC:2.7.1.108.	2.27328e-29
NZ_AP022587.1|WP_163789908.1|2136849_2137317_-|nuclear-transport-factor-2-family-protein	gnl|CDD|369560	pfam07858, LEH, Limonene-1,2-epoxide hydrolase catalytic domain. Epoxide hydrolases catalyze the hydrolysis of epoxides to corresponding diols, which is important in detoxification, synthesis of signal molecules, or metabolism. Limonene-1,2- epoxide hydrolase (LEH) differs from many other epoxide hydrolases in its structure and its novel one-step catalytic mechanism. Its main fold consists of a six-stranded mixed beta-sheet, with three N-terminal alpha helices packed to one side to create a pocket that extends into the protein core. A fourth helix lies in such a way that it acts as a rim to this pocket. Although mainly lined by hydrophobic residues, this pocket features a cluster of polar groups that lie at its deepest point and constitute the enzyme's active site.	1.56837e-17
NZ_AP022587.1|WP_163789895.1|2118446_2118779_-|DUF732-domain-containing-protein	gnl|CDD|368380	pfam05305, DUF732, Protein of unknown function (DUF732). This family consists of several uncharacterized Mycobacterium tuberculosis and leprae proteins of unknown function.	8.41844e-26
NZ_AP022587.1|WP_170313037.1|2118929_2119661_+|CDP-alcohol-phosphatidyltransferase-family-protein	gnl|CDD|223632	COG0558, PgsA, Phosphatidylglycerophosphate synthase [Lipid metabolism].	2.53175e-06
NZ_AP022587.1|WP_170313087.1|2133722_2134187_-|CAP-domain-containing-protein	gnl|CDD|349398	cd05379, CAP_bacterial, Bacterial CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain proteins. Little is known about bacterial and archaeal members of the CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain family. The wider family of CAP domain containing proteins includes plant pathogenesis-related protein 1 (PR-1), cysteine-rich secretory proteins (CRISPs), and allergen 5 from vespid venom, among others. Studies of eukaryotic proteins show that CAP domains have several functions, including the binding of cholesterol, lipids and heparan sulfate. This group includes Borrelia burgdorferi outer surface protein BB0689, which does not bind to cholesterol, lipids, or heparan sulfate, and whose function is unknown.	8.31122e-27
NZ_AP022587.1|WP_163789905.1|2133170_2133710_+|restriction-endonuclease	gnl|CDD|377369	pfam04471, Mrr_cat, Restriction endonuclease. Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA.	2.68841e-29
NZ_AP022587.1|WP_163789898.1|2121199_2122930_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.64354e-67

Protein sequences

>NZ_AP022587.1|WP_163794641.1|2129301_2129655_-|hypothetical-protein
MSGVGFKLDEIQDTEIYGDRAAWASYYRGEDCKLQVCWSARDDGIDFMLAPLDAPNEFGLVNRSKKWQFMLMLSNAHVGRAAPGLDADENEVMSRLEALFKVHFPSACDALRSRDAR
>NZ_AP022587.1|WP_163789902.1|2128860_2129277_-|hypothetical-protein
MTEEFLAGVRSIVEPLLNELGFQLDEYDDDVVEGGANSSVVYYSSADCKIQIYESPRAASINCMIAPLDAPNVFGPSDRSGKWQYIFMLAIRQGIPRDEIRKDQLKVDFPTTIQRLEWIRGSIEKYFSVARDSILQGG
>NZ_AP022587.1|WP_163789901.1|2127573_2128404_-|TIGR03619-family-F420-dependent-LLM-class-oxidoreductase
MKFGVATFVNDDTIDTVSLARGIEERGFTSLVIAEHTHIPASRESPYPMGGELPSIYYRTLDPFVTLAAAAAVTSSIELFTGIALLIQRDPIITAKEAASIDLISGGRFIFGVGAGWNIEELRDHGTDPKTRGALLDERIEAIKALWTTEPAEYHGKHVNFDSSYLRPKPVQTPHPPIFIGGDSDATVKRVIRHDAGWISNPLPLEHLAKRIDQLREGSGRDVPLAMFGTPAKPDYWQAAQDLGYGRLALLLPSRPLDESLRLLDDYAAKVDSYQG
>NZ_AP022587.1|WP_163789900.1|2126676_2127498_-|methyltransferase-domain-containing-protein
MELKAPEFRPSPLWTLKAKFIQFIYQYFYPYLTRRLRSDDVLFLNYGYEEDPPMGVPLPASDEHDRYFIQLYHRIATQVDLAGKRVLEVGCGHGGGASYLMRTTHPASYTGLDLNPVGIAFCQQRHHLDGLEFVKGDAEQLPFPDQSFDAVINIESSHLYREFPRFLDEVGRVLSPGGHFLYADFRFADTVAAWEAQLANAPMSMLSHRTINEQVMRGMEKNSQWWMRAVERLVPAFLHRWLLVHGYVLVWRVYQDMQRGGSTDYRMYCFAKA
>NZ_AP022587.1|WP_163789899.1|2124703_2126479_+|NAD-binding-protein
MGELFQFHREIIVSGDDPLSKTIAEELRGAGARLIKINTAADLLGAGVHRARAVVCAGPNDAVNLEIALLAREYSPNVRVVARLANDVLREAVTTVNGPGAILDVADLAAPSLVEAVLSRNAHQFDTAGIEFVVWGSEAPYNATLREIYADLAPVAVVHGKNSPAPGEVVPCPGRDLQVYAGDWTSMIGVKDELEARGFTLPPATATRSRHSRIRRAIDAARTMRDDVNPLLLPSLVFALFLTLGSTAVEQFAYQHQQMSWLDALYFTSETITTVGYGEFGFGEESVFLRLFNVGLMFGGAIVTAILVAFLADLMLSRRFVQTAGLRRARHMRDHIVVIGLGSIGVRVVSDLATAGYDVLVIEPNVNNRFLPTVAELDVPVIFGDSAMRQTLESARVDRARGVAVVTQDDMENIETGIVLLEILGSDTKVPIVMRVQGRALGTAVNRRFGFENVRSIVDLAAPWFIGAAMGLQVLGTFWVGQRSFMVGGMLVAEGSELDGLRMVDLSTQTRVIAITRPEGPVRLRPRRDALLKAGDTVYVIGPYRELIATLRKGQPPPLTAVNGERAATLAAARAHRPDVRRPRWAPEQQA
>NZ_AP022587.1|WP_163789898.1|2121199_2122930_+|ATP-binding-cassette-domain-containing-protein
MRNQMTCSVAPTITTRIPRATMVGGLDVRDVSLTLERNIVALDQISFAARPGTLTAVIGPSGAGKSTLARVITGAARPSGGAVALDGRDLHTASSKSLRHRIGMVPQDDVVHPRLTVGQALEFAAELRMPADTAACDRRQVIASVLEELELTTYTATRIEKLSGGQRKRVSIALELLTRPSLLVLDEPTTGLDPALDRAVMTTLRRLADAGRVIVVVTHSLTFLDVCDQVLLLAPGGKTAFCGRPGEIGSAIGARDWADIFSIVCADPDGMRRRFMHGMGSQDALTAIQVICHQPAQRSEPAGPGRWRQLWTLARRQVRLLVANRGYFVFLAALPFIVGLLPLTVAGHAGLGHADGSVPFEAKHVIALMSFAAILMGVTLTARDLVGERAIFHREQAAGLSTSAYLLAKIVVFGGAATLQSAILVLLVTAPGIGKPGPSGAAALGSPMLELFVGVAATCVVAMVAGLAISALARTSDQVIVLLAMTLMTQLVLAGGFIPVTDRPLFEILAWFTPGRWGFAATASTADLTHLVVGIANDPHWRRAESAWFFDMAMLAVLGLTFAGFAWWKSRPTVRA
>NZ_AP022587.1|WP_163789897.1|2120294_2121203_+|phosphatidate-cytidylyltransferase
MTIVEKYLSFVHRDRRMPLHVDLGPMHIHLYSRAVFLLWVTVAILALAGIVVLVSRKRELIQKWRTWALIAPAVGLPVWLGHGTTAALAAALAVVAVIEYARLVRLRRLDTCVLVALAVLYPIAAWLRPSLLQLAPAAVLLCALPSVFGGDVEHGAKRTAFAGFGSVWICWSLAHLVMVWPDTYLLCFAVAATDVAAWCGGKGLRRMAWARRPLSPLSPNKTVGGMVGAIIGASVILSLLGTISIGLLVAVSIGGVFGDLLESMFKRQAQVKDAGCWLPGFGGLLDRIDSLLLVLPLAYLLG
>NZ_AP022587.1|WP_163789896.1|2119657_2120293_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase
MTANRMPSVLRHGLWRTVCAASGGLTVSGRWRATGACVVVANHSSHADSAVLLAALPPATRPVIGAAADYWFAVPTRRAVATSLIGVLPVRRSGDGTYAALLAAAGPALKAGRTVVIYPEGTRSTDDTIGEFRSGALRLACDCGVPILPVAIAGTADVLPKNGRYSPAPMRVQIGAPLDPHTTSAPQLRAHVLALREDAGAELVDRYALAS
>NZ_AP022587.1|WP_170313037.1|2118929_2119661_+|CDP-alcohol-phosphatidyltransferase-family-protein
MTSLYALKPWFTRRLTPIVDAAVARQVSPDVFTAAGVTAAAAAGVAVAFGCWPLAALFMVLRLAGANLDGAVARARGVSRPWGFVVNELGDRTADLFAFAGLAVWAARQHGPGLHWLSWLVFQVLVATLAATLPTFASLAAAAAGATRRNGGPLGKTERCLFVVLATAFPVVMPVLLAQLVNGSLITTVLRLRAARRELKPQRVVLVEHFDAVTQPIDVVTQPINTITRPLNLVTRPLAAVAA
>NZ_AP022587.1|WP_163789895.1|2118446_2118779_-|DUF732-domain-containing-protein
MRGVIVFAGVAAVIAVAAPAQADPSPDSNFLTQLKNAGITYQTPSIAIGVGKSECKLMDEGMPETEVIKDLEESNPAFKGDSPVQFTSIAVNTYCPQHAGELTNQLPASS
>NZ_AP022587.1|WP_163794642.1|2131619_2131916_-|RNA-2'-phosphotransferase
MDVDLVALHVGSNQVLNGIGEAAIDFAGHEDGLAEATPGWIGSSQLALGQLAARWETQHSHHKLRVGGLGTHVAEAMVAFATNEDDSASAIRSVREQG
>NZ_AP022587.1|WP_163789904.1|2132136_2132946_+|SDR-family-NAD(P)-dependent-oxidoreductase
MSQPHPLDRYVGSWALVTGSARERGLGFAYACEIASRRVNLVLVDILAEELEARAATLRTEYGVEVRTITVDLGDLSVYPRILERLADITVDVLVCNRMYTPKDTPKILDMSLGVHNAMIDVNARAYVNLIYPFAHLMTRRGRGAIVIVSSGAGLIPAPYTGAYAANKAFQTVFGEVLWYETRGTGVDVLVMSAGLMDTQGHTLSQYPRWQIAAPRDAAAETLSAIGRRHLVMPGRPNRFTTLLTTRLIPRRRAVMTMGRFMERGLGKN
>NZ_AP022587.1|WP_163789905.1|2133170_2133710_+|restriction-endonuclease
MRIAFIFLPLYFGLLLGYFTHRVALGLVGACCGLLFAGLIQPAYRRSRRRPRTHAAISEVDAMDGVEFEDYVAARMQRAGWEVSFTPAVGDYGVDLIAQKDGQYAAIQCKRHGKTVGVAAVQQVVAGARHHGCTRSIVVSNQEFTTAAKQLAYTHGCQLIGRKALRSWVPAPTGKALRD
>NZ_AP022587.1|WP_170313087.1|2133722_2134187_-|CAP-domain-containing-protein
MTRKVKIAAVLSLGAFSLTAPRTVANFRAHADESLYSGVNLVREGCGAIGNDPRLTEAAQRHANDMLRSGVNGHIGSDGSSPQVRITDAGYRTPYSGEVVFWGTGSAANPNEALDLWMQSPPHRAIILNCAYTEVGFATASDGNKMTIVGDFAA
>NZ_AP022587.1|WP_163789906.1|2135009_2135324_+|hypothetical-protein
MKSKLSRIGAALLGCTAALTVSAGVASAEPPDPHLPNITRNWCEGARMWGYICDGAPYADGSYWHQWEDEYTYHYDCVSGNEPFPAPPPPGGCNGAIPPAPPPP
>NZ_AP022587.1|WP_163789907.1|2135346_2136765_-|SDR-family-NAD(P)-dependent-oxidoreductase
MKAIDPDKLDVCLQVLADIESLPPEHPDAVTVRRATAGIFKSVKKARRNAKRDEIAAADRAVVAATATGAPGRIDDETQGLPLVSTTVGASAGTLRRSRACDICKNHYTVVDAFYHQLCPGCAALNRAKRDARTDLTGRRALLTGGRAKIGMYIALRLLRDGADTTITTRFPNDAVRRFATMPDSGDWLHRLHVVGIDLRDPAKVVALADTVAGQGPLDILINNAAQTVRRAPGSYAALVESECTPAPALVDVITFDRVSDAHPAALAGSLAEHQTPHAVTELALAARSASPDRIAAGTAIDAGGLLPDTASINSWTQRVHEVDPMELLEVQLCNQTAPFILVSRLRPAMAASPARRKYVVNVSAMEGQFSRKYKGPGHPHTNMAKAALNMLTRTSAGEMLAQDGILMTAVDTGWITDERPHPTKLRLAEEGFHAPLDLVDGAARVYDPIVRGEAGEDLRGCFLKDYSPSNW
>NZ_AP022587.1|WP_163789908.1|2136849_2137317_-|nuclear-transport-factor-2-family-protein
MPVKTASDTTSDQHELRALEFFAAWGESFDAMCTPFNVLASEGVWDQRPIPKLTGPRQAMRFLRIAHRVLGLATIDVEILSIASNDDVVHTARIDRLRRADGTLIAAAPVAGVLTFDAGKITHWREYFDATGFLAQTVATSLTHPIRRLGGSLRP
>NZ_AP022587.1|WP_163789909.1|2137412_2138042_+|hypothetical-protein
METSRPSGQTIRHHYYLALIQCRDDVLEMRRLFQAERYQATILISIQQHGLPPEGSAMSYRVQLLCAWAGPATVLVTLLGWLIAGILPIPLGSSSSTQEVVNFYGHDTRVLSGLVISQLGICLVFPLIGLIGYFLLRIEGRRPILTFVQLVTGAATGVLLLLPMLLMAVIAFRPYRNPEITVTLNDIAWLGGFKVWLQQLCLSGWTVAC
>NZ_AP022587.1|WP_163789910.1|2137989_2139255_-|IS30-family-transposase
MLMTGQPQLLVVQRRYWDLIAAGWSSEDAGVAVGVSATCGSKWFRRFGGVNPRWSKPQGQRRPRLSADEREQIMIGTAHGESIRSMARRLGRAPSTIMREIAHNGVMRGHVGRYRARYRFRARRAGWDAKSGYSARIAQRRSEQRARRPKTGKLGRCEQLRAEVQALLVNKYSPEQIAGVLTATYPDRPEMQVSHETIYQALYVQGRGELRRELRTCLRTGRALRKPRRRACAGDGRGRIQGMVNISERPAEANDRAVPGHWEGDLIIGKDQASQIGTLVERSTGYVRLLHLPHTRSAEAVAEAMIAAVKDLPATLRRTVTWDQRHEMAHHARISIDTGIEVYFCDPHSPWQRGSNENTNGLLRQYFPKGTDLSVHDAEHLAYVADELNGRPRKRFNWDNPTNRLNKLLSTPTDTTVATKP
>NZ_AP022587.1|WP_163789911.1|2139271_2139604_+|hypothetical-protein
MQPPLELKLVFLTPIAPFIIQNVVIGIAILSDQAQILPRWVGYLNFWIAASFLPDVLAFFFHSGPLSWRGVLVFWLALTTYSVFLVGMGLVMRSAILRSASAADPTTLGG

Crispr_ID: NZ_AP022587_2

• CRISPR_ID: NZ_AP022587_2
• CRISPR_location: 3994191-3994271
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_AP022587_2

Consensus_repeat	Method
TACCCGGAGCAGGGCGGCTATCCG	CRISPRCasFinder

spacers of NZ_AP022587_2

>2.1|3994215|33|NZ_AP022587|CRISPRCasFinder
GAGCAGGGGGGCTACCAAGACCAGCGCGGCGGC

CRISPR arrays and Neighbor proteins around NZ_AP022587_2

CRISPR arrays

The CRISPR arrays of NZ_AP022587_2

>merge|NZ_AP022587|2|3994191-3994271|CRISPRCasFinder
TACCCGGAGCAGGGCGGCTATCCGGAGCAGGGGGGCTACCAAGACCAGCGCGGCGGCTACCCCGAGCAGGGCGGCTATCCG

>NZ_AP022587|2|2|3994191-3994271|CRISPRCasFinder
TACCCGGAGCAGGGCGGCTATCCG	GAGCAGGGGGGCTACCAAGACCAGCGCGGCGGC
TACCCCGAGCAGGGCGGCTATCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP022587.1|WP_163791403.1|4001569_4003444_+|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase	unknown	unknown	gnl|CDD|270916
NZ_AP022587.1|WP_163791405.1|4004168_4004912_-|DUF881-domain-containing-protein	unknown	unknown	gnl|CDD|226396
NZ_AP022587.1|WP_163791399.1|3995763_3997287_+|protein-phosphatase-2C-domain-containing-protein	unknown	unknown	gnl|CDD|223704
NZ_AP022587.1|WP_163791401.1|3998689_4000168_+|D,D-transpeptidase-PbpA	unknown	unknown	gnl|CDD|223839
NZ_AP022587.1|WP_163791404.1|4003421_4004120_-|aminodeoxychorismate/anthranilate-synthase-component-II	unknown	unknown	gnl|CDD|181107
NZ_AP022587.1|WP_163791389.1|3985645_3986431_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|197775
NZ_AP022587.1|WP_163791398.1|3995228_3995696_+|growth/cell-division-associated-protein-FhaB	unknown	unknown	gnl|CDD|224630
NZ_AP022587.1|WP_163791400.1|3997283_3998693_+|FtsW/RodA/SpoVE-family-cell-cycle-protein	unknown	unknown	gnl|CDD|279444
NZ_AP022587.1|WP_163791395.1|3991566_3992454_-|hypothetical-protein	unknown	unknown	unknown
NZ_AP022587.1|WP_163791402.1|4000241_4001573_+|protein-kinase	unknown	unknown	gnl|CDD|270916
NZ_AP022587.1|WP_163791388.1|3984854_3985649_-|C40-family-peptidase	unknown	unknown	gnl|CDD|366353
NZ_AP022587.1|WP_163791387.1|3984476_3984839_-|DUF4226-domain-containing-protein	unknown	unknown	gnl|CDD|371237
NZ_AP022587.1|WP_163791396.1|3992482_3992767_-|hypothetical-protein	unknown	unknown	unknown
NZ_AP022587.1|WP_163791394.1|3990194_3991562_+|PPE-domain-containing-protein	unknown	unknown	gnl|CDD|366325
NZ_AP022587.1|WP_163791392.1|3988524_3989505_+|pirin-family-protein	unknown	unknown	gnl|CDD|224655
NZ_AP022587.1|WP_163791390.1|3986576_3986993_+|WhiB-family-transcriptional-regulator	unknown	unknown	gnl|CDD|376791
NZ_AP022587.1|WP_163791407.1|4005467_4005893_+|PH-domain-containing-protein	unknown	unknown	gnl|CDD|371225
NZ_AP022587.1|WP_163791406.1|4005030_4005312_+|cell-division-protein-CrgA	unknown	unknown	gnl|CDD|178907
NZ_AP022587.1|WP_163791391.1|3987088_3988471_+|acyl-CoA-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|173847
NZ_AP022587.1|WP_163791393.1|3989501_3989843_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379642

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP022587.1|WP_163791403.1|4001569_4003444_+|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	7.59201e-130
NZ_AP022587.1|WP_163791405.1|4004168_4004912_-|DUF881-domain-containing-protein	gnl|CDD|226396	COG3879, COG3879, Uncharacterized protein conserved in bacteria [Function unknown].	3.64393e-76
NZ_AP022587.1|WP_163791399.1|3995763_3997287_+|protein-phosphatase-2C-domain-containing-protein	gnl|CDD|223704	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms].	5.06837e-84
NZ_AP022587.1|WP_163791401.1|3998689_4000168_+|D,D-transpeptidase-PbpA	gnl|CDD|223839	COG0768, FtsI, Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane].	3.38847e-107
NZ_AP022587.1|WP_163791404.1|4003421_4004120_-|aminodeoxychorismate/anthranilate-synthase-component-II	gnl|CDD|181107	PRK07765, PRK07765, aminodeoxychorismate/anthranilate synthase component II.	6.52323e-153
NZ_AP022587.1|WP_163791389.1|3985645_3986431_-|helix-turn-helix-domain-containing-protein	gnl|CDD|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	6.07845e-08
NZ_AP022587.1|WP_163791398.1|3995228_3995696_+|growth/cell-division-associated-protein-FhaB	gnl|CDD|224630	COG1716, COG1716, FOG: FHA domain [Signal transduction mechanisms].	4.94141e-32
NZ_AP022587.1|WP_163791400.1|3997283_3998693_+|FtsW/RodA/SpoVE-family-cell-cycle-protein	gnl|CDD|279444	pfam01098, FTSW_RODA_SPOVE, Cell cycle protein. This entry includes the following members; FtsW, RodA, SpoVE.	3.48427e-106
NZ_AP022587.1|WP_163791402.1|4000241_4001573_+|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	8.852e-118
NZ_AP022587.1|WP_163791388.1|3984854_3985649_-|C40-family-peptidase	gnl|CDD|366353	pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.	8.56594e-28
NZ_AP022587.1|WP_163791387.1|3984476_3984839_-|DUF4226-domain-containing-protein	gnl|CDD|371237	pfam10774, DUF4226, Domain of unknown function (DUF4226). This family of mycobacterial proteins are uncharacterized.	9.82472e-29
NZ_AP022587.1|WP_163791394.1|3990194_3991562_+|PPE-domain-containing-protein	gnl|CDD|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	2.17711e-56
NZ_AP022587.1|WP_163791392.1|3988524_3989505_+|pirin-family-protein	gnl|CDD|224655	COG1741, COG1741, Pirin-related protein [General function prediction only].	4.78015e-57
NZ_AP022587.1|WP_163791390.1|3986576_3986993_+|WhiB-family-transcriptional-regulator	gnl|CDD|376791	pfam02467, Whib, Transcription factor WhiB. WhiB is a putative transcription factor in Actinobacteria, required for differentiation and sporulation.	9.34893e-08
NZ_AP022587.1|WP_163791407.1|4005467_4005893_+|PH-domain-containing-protein	gnl|CDD|371225	pfam10756, bPH_6, Bacterial PH domain. This domain has a bacterial type PH domain structure. This domain was previously known as DUF2581. This family is conserved in the Actinomycetales. Although several members are annotated as RbiX homologs, RbiX being a putative regulator of riboflavin biosynthesis, the function could not be confirmed.	2.95559e-11
NZ_AP022587.1|WP_163791406.1|4005030_4005312_+|cell-division-protein-CrgA	gnl|CDD|178907	PRK00159, PRK00159, putative septation inhibitor protein; Reviewed.	2.97545e-47
NZ_AP022587.1|WP_163791391.1|3987088_3988471_+|acyl-CoA-dehydrogenase-family-protein	gnl|CDD|173847	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases. Short chain acyl-CoA dehydrogenase (SCAD). SCAD is a mitochondrial beta-oxidation enzyme. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of SCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. This subgroup also contains the eukaryotic short/branched chain acyl-CoA dehydrogenase(SBCAD), the bacterial butyryl-CoA dehydorgenase(BCAD) and 2-methylbutyryl-CoA dehydrogenase, which is involved in isoleucine catabolism. These enzymes are homotetramers.	8.14314e-116
NZ_AP022587.1|WP_163791393.1|3989501_3989843_+|GNAT-family-N-acetyltransferase	gnl|CDD|379642	pfam14542, Acetyltransf_CG, GCN5-related N-acetyl-transferase. This family of GCN5-related N-acetyl-transferases bind both CoA and acetyl-CoA. They are characterized by highly conserved glycine, a cysteine residue in the acetyl-CoA binding site near the acetyl group, their small size compared with other GNATs and a lack of of an obvious substrate-binding site. It is proposed that they transfer an acetyl group from acetyl-CoA to one or more unidentified aliphatic amines via an acetyl (cysteine) enzyme intermediate. The substrate might be another macromolecule.	1.95824e-27

Protein sequences

>NZ_AP022587.1|WP_163791396.1|3992482_3992767_-|hypothetical-protein
MFYPKWVRKERRRGQRSGDHKEIREAVVGYAQERADTLSAGVSQPNTLSSNKIQCQNRTGERIEADRRNERILTNGPAQLCSPGIMPGNLEQAR
>NZ_AP022587.1|WP_163791395.1|3991566_3992454_-|hypothetical-protein
MPRKPELARRFYDRFEPVHAVTYFAPEARAALDELAYRGYWMGYFAARSAPLGTPSPELVTAIFHNFAPQRVAKALPAAWQIAGPDAALRARRDAAVAALRRYGLEDDENASTAAELAGKAARQAGVDGRPLFAANLALPWPDNPLGALWHATTLLREHRGDGHVAVLTAAGISGRECNVLHAAADRVPRDYIARTRDYDETEWRHHEQRLAERGLLNDDGSLTAAGAELKDRVEASTDALGLSALDALSDDEVETLFQALTPITRVVVEGGDVPSATPMALRRTELYDASAHLG
>NZ_AP022587.1|WP_163791394.1|3990194_3991562_+|PPE-domain-containing-protein
MDYALLPPEVNSARIYAGPGSGPMLAAASAWQTLAAELHSTASAYQAAITELTSGPWLGPAAAMMAAAAAPYVSWMRTAADQAEETGNRAIAAAAAYEAAFAETVPPPVVAANRAVLSTLVATNFLGQNTSAIAAVEGQYGEMWAQDTGAMQSYATQSAAATALTPFDSPSPNTSTDGTADQAAAVAQATGTTAGDAQDAVSSAQQAFSAVPNALINLASPQDAFGFGGRDLLGLLADLSAVFLDPELGATSLAADTTLGTTALPYDVGGYYTGVHTDDIVSGWGGVQPWPGNASAPPTTFPVLTNPPATVTGGFGHAPSVGRLSVPPGWMTAAPALRAATTALPAATAAAAAEATGSSAGSLFSQMALASMAGRAMAGTTGGGGARFQERIGMAAPKSKDTPPAEPVEVPQIPMGGPITSIAAELRKLASLRDAGILTQEEFVEQKQRLLPRDP
>NZ_AP022587.1|WP_163791393.1|3989501_3989843_+|GNAT-family-N-acetyltransferase
MTTDKTGAQTTVAEGHQTYTITVEGKTVGQADYADRGEQRVFYHTVVDPEFGGRGLATILLEEALNKARDSGKRIVPVCSMVQTVLKKHPEFDEFTDPVTDEVKVWAHSQPSS
>NZ_AP022587.1|WP_163791392.1|3988524_3989505_+|pirin-family-protein
MSNLETTPTEVACSASRVAGVEVLQPREVPLGGPRAIRVQRTLPQRQRSLIGAWCFIDHYGPVRARMDVPPHPHTGLQTVSSLFSGEVEHRDSAGVHSMVRPGELNLMTAGAGISHSEVSVGSDAALHGVQLWVALPDSDRDGGRGFAHHVPDPISLTGAVARVFLGELAGSRSPVHTFTPLLGAQIDLDANAQLHLDVDPTFEHGVLCDVGTVTMNGTDLAVGDLGYQGAGNASVRLCNVGDRPARVVLLGGAPFSEELLMWWNFVGRTHDKIVGYRQLWEEADPRFGVVEGYRGSVTRLPAPPLPTARLRPRPTPRGPNEKENT
>NZ_AP022587.1|WP_163791391.1|3987088_3988471_+|acyl-CoA-dehydrogenase-family-protein
MTFDLTPTAAQHDLARRAHEFAESVVRPVALEYDQRQEFPWPVLEEAAQRGFYSPLFYRDLIGDPTGLSLPMFMEELFWGCAGIGLAIVMPALALSAIGQAASPEQMLQWAPECFGTPGDLKLAALAISEPEGGSDVRNLRTRARRDGEDWVLDGHKMWIGNGGIANVHVVNAVVDEELGHRGQALFVVPGGTPGLELVRKLDKLGCRASHTAELRLDSVRIPGANLLGGEDKLEHKLAKAREVVAGGQRSGSATLGTFEQTRPMVAAQAIGIARAAVEYATTYATEREAFGAPIIDNQGIAFPLADLATQIDAARLLTWRASWMAANDVPFERGEGSMAKLAASEVAIKATERAIQTLGGWGYITDHPVEKWYRDAKLYTIFEGTSEIQRMVISNALGAAVGTPPLHVVLEPSGGPLNRIFGRGTPLRSRAANAALSVKDQIPEPIMRVAMQLLRPPGR
>NZ_AP022587.1|WP_163791390.1|3986576_3986993_+|WhiB-family-transcriptional-regulator
MGHPCATDPELWFGYPDDDSGDGAAKARAYERSATEARRQCLRRCPLAQQRRCAQYAIAHREEYGVWAGVKLPGGQYRKRDQLARAHDVLRRIAAGEINSRQLPENAALLARSEHETIPMPAVVVHLPIAQVGPRSAA
>NZ_AP022587.1|WP_163791389.1|3985645_3986431_-|helix-turn-helix-domain-containing-protein
MSRESAGAAIRALRESRDWSLAELAAATGVSIMGLSYLERGARKAHKSTVQKVENGLGLPPGTYSRLLVAADPDAELARLIAAQPLEAMSPPRAGAVVVDRHSDTEVLEGYAEAQLDALKSVIDRLPATTSNEYETYILSVIAQCVKAEMLAASSWRVAVSAGADSTDRLMEHLQALEETRSALLKRMPTSLSARFDRACAQSSLPDAIIAALLGVSSDEMWDIRNRGVIAAGVLPRVRAFTDAVEAESRDGTDLGGEEDR
>NZ_AP022587.1|WP_163791388.1|3984854_3985649_-|C40-family-peptidase
MTESDIEALSRAHQLFAGSTRQLPLDAYVMAPLNSVVGQESYQSKVNRSQQVLRAAARTDAAATEIIAGAHRDRAQARQLTKNVLDEARADAAATPITPMAQREAMRRRAARLCAQRAHVLTARLRARRHSAALRALRYRMLHHRGLRLPSRSSRAGIAVRAALSRLGRPYVWGATGPDQFDCSGLVQWSYAQAGIHLDRTTYQQINDGIPVPRSQVRPGDLVFPHTGHVQMAIGNNLVVEAPYSGASVRISRLGNYVAIRRPL
>NZ_AP022587.1|WP_163791387.1|3984476_3984839_-|DUF4226-domain-containing-protein
MSEQTGPSVPAIQARQSEMATRHDSVAEADRALMEVLASAHAATRESIRRLDAIADEIDRAVPQHRSLALDTPMGAREFQKFLVAKQREITAVVADARELDRAKTAVLQSVRGEYGISTG
>NZ_AP022587.1|WP_163791398.1|3995228_3995696_+|growth/cell-division-associated-protein-FhaB
MQGLVLQLTRAGFLMLLWVFIWSVLRILKTDIYAPTGAVMVRRGLALRGTLLPSRQRRHAARYLVVTEGALAGARITLSGQPVLIGRADDSTLVLTDDYASTRHARLSQRGLEWYVEDLGSTNGTYLDRAKVTTAVRVPIGTPIRIGKTAIELRP
>NZ_AP022587.1|WP_163791399.1|3995763_3997287_+|protein-phosphatase-2C-domain-containing-protein
MAPVTLVLRYAARSDRGLVRANNEDSVYAGARLLALADGMGGHAAGEVASQLVIAALAHLDDDEPGGDLLAKLDTAVRSGNSAIAAQVEMEPDLEGMGTTLTAILFAGNRIGLVHIGDSRGYLLRDGELTQITKDDTFVQTLVDEGRITKEEAHSHPQRSLITRALTGHEVEPTLTMREARAGDRYLLCSDGLSDPVSDETIHEALQIPDVAESAYRLIELALRGGGPDNVTVVVADVVDYDYGQTQPILAGAVSGEEDQLTLPNTSAGRASAIGPRKEAAKRVVPQEEPAPRPRFAWRRMFIVVTLVVLLALTGLAVGRAIIRSNYYVAEYNGMVSIIRGIQGSLLGMSLHEPYLVGCLNARNDLSIISFGQSGGHLDCRLMQLEDLRPAARAQVLAGLPAGTLDEAESQLKELSANNLLPPCPPPRATSPPAPPSPVTSGATPPSATAPPTPSSGTPPTSTPANPGPVSTTPAAPATTSPTTPPQTVTTLPPLPPQPGIDCRAAA
>NZ_AP022587.1|WP_163791400.1|3997283_3998693_+|FtsW/RodA/SpoVE-family-cell-cycle-protein
MTTQVQPPVTLAPSLPTRRNSELLLLCFAALITVAALLIVDANQERGLRWGIASYGLGFLALFGGAHLAIRRFAPYTDPLLLPIVALLNGLGLVMIHRLDLVGNELSGRHHPSATQQVLWTLVSVAAFALVVTFLKDHRQLARYGYIFGLTGLIFLAIPAILPATLSEQNGAKIWIRLPGFSIQPAEFSKILLLIFFSAVLVAKRSLFTSVGKHLMGMTLPRPRDLAPLLAAWVISIGVMVFEKDLGTSLVLYASFLVVVYLATQRFSWVVIGLVLFAAGSVVAYFIFAHVRTRVQMWWDPFSDPDGSGYQIVQSLFSFATGGIFGTGLGNGQPDTVPAASTDFIIAAFGEELGLVGLAALLMLYTIVIVRGMRTAIATRDSFGKLLAAGLASTLAIQLFIVVGGVTQLIPLTGLTTPWMSYGGSSLLANYVLLAILARISHSARRPLRSHTRDTSPIATAGTEVIQKV
>NZ_AP022587.1|WP_163791401.1|3998689_4000168_+|D,D-transpeptidase-PbpA
MNTSLRRISMTVMALIVLLLLNATMTQVFAADGLRADPRNQRVLLDEYSRQRGQIIAGGQLLAYSVATDSRFRFLRVYPNPAVYAPITGFYSLRYSSSGLERAEDSLLNGSDERLFGRRLADFFTGRDPRGGNVDTTINPRMQQAAWDAMQQDCGGPPCKGAVVALEPSTGKILAMVSSPSYDPNLLSSHDPEVQAQAWQRLRDDPDNPLTNRAISETYPPGSTFKVITTAAALQAGAKDDEQLTAAATIPLPNSTATLENYGGTPCGDQPTVSLSEAFAKSCNTAFVQLGILTGSEALRSMAHSFGLDSSPGVIPLQVAESTVGIIADAAALGMSSIGQKDVALTPLQNAEIAATIANGGVTMQPYLVESLKGPDLANISTTAPYQQRRAVSPQIAAKLTELMVGAEKAAQQKGAIPGVQIASKTGTAEHGADPRNTPPHAWYIAFAPAQSPKVAVAVLVENGADRLSATGGALAAPIGRAVIQAALQGGP
>NZ_AP022587.1|WP_163791402.1|4000241_4001573_+|protein-kinase
MSPRVGVTLSGRYRLQRLIATGGMGQVWEAVDSRLGRRVAVKVLKAEFSQDPEFIERFRAEARTTAMLNHPGIAAVHDYGESQMDGEGRTAYLVMELVNGEPLNSVLKRTGRLSLRHALDMLEQTGRALQIAHAAGLVHRDVKPGNILITPTGQVKITDFGIAKAVDAAPVTQTGMVMGTAQYIAPEQALGHDATPSSDVYSLGVVGYEVVSGKRPFTGDGALTVAMKHIKEPPPPLPPELPPNVRELIEITLVKNPGMRYRSGGPFADAVAAVRAGRRPPRPSQSPPPGRASPAAIPSNPQTRSAAAVSPRTAAPRRSQPTTSRRQPPARRTFSSGQRALLWAAGVLGALAIIIAVLIVINSRGDNPQQQPPPPTVTDTGTPPANGPPPASKTPSGSAPSLRLDWTDRGGISNSGFHSRPPELSWATPLTPSLSTARHETPQ
>NZ_AP022587.1|WP_163791403.1|4001569_4003444_+|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase
MTTPQHLSDRYELGDILGFGGMSEVHLARDVRLHRDVAVKVLRADLARDPSFYLRFRREAQNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRDIVHNDGPLPPRRAIEIIADACQALNFSHQNGIIHRDVKPANIMISTTNAVKVMDFGIARAIADSGNSVTQTAAVIGTAQYLSPEQARGDSVDARSDVYSLGCVLYEMLTGEPPFTGDSPVSVAYQHVREDPVPPSKRHAGISPDLDAVVLKALAKNPDNRYQTAAEMRADLVRVHNGEPPEAPKVFTDAERTSMLTSVGPGHSPRTDPPRQRLADADPDRMGGPVGRWVVAVAVLAVLTIVVVIAFNTFGGSTRDVQVPDMRGQVSADAVAALQNRGFKTRTLQKPDSSIPPDHVISTDPGANASVAAGDEITINVSTGPEQREVPDVSSMSYSDAVSKLKAAGFTKFKQANSPSTPELLGKVIGTNPPANQTSAITNVITVIVGSGPETKQVPDVAGQTVDIAQKNLTVYGFTKLTQTAVDSPRPAGEVIGTNPPKGQTVPVDSIVELQVSKGNQFLMPDLTGMFWTDAEPRLRALGWTGVLDKGADVDAGGSQSHKVVYQNPPAGAGVNRDGIITLKFGQ
>NZ_AP022587.1|WP_163791404.1|4003421_4004120_-|aminodeoxychorismate/anthranilate-synthase-component-II
MRILVVDNYDSFVFNLVQYLGQLGVEADVWRNDDARLLDPPGGHAAIATQFDGVLLSPGPGTPERAGASIDLVRACAAAATPLLGVCLGHQAIGVAFGATVDRAPELLHGKTSSVHHTNVGVLQGLPDPFTATRYHSLTILPESLPPVLEATAHTRSGVIMAVRHTELPIHGVQFHPESLLTEGGHRMLANWLAYCGWLRDDTLIRRLENEVRSAVRPYFPADPAATDRTSA
>NZ_AP022587.1|WP_163791405.1|4004168_4004912_-|DUF881-domain-containing-protein
MTQTHRSPWRFGVPLVCLLAGLLLAATHGVSGGAEIRRSDAPRLVDLVRETQASVSRLKAERDELAGKIDSTHLRSSDAALAAMLRRSAELAAGADMTPVHGPGLVVTLDDAQRDANGRFPRDASPDDLVVHQQDIQAVLNALWSAGAEAVQMQDQRIIATSVPRCVGNTLLLNGRTYSPPYTITAIGNAAAMQAALAAAPLVILYRQYVVRFGLGYHEDAKPDVQLVGHSEPVRMHFAQPAGPVGY
>NZ_AP022587.1|WP_163791406.1|4005030_4005312_+|cell-division-protein-CrgA
MPKSKVRKKNDFTVSAVSRTPVKVKVGPSSVWFVTLFVGLMLIGLVWLMVFQLAAVGSQAPTALHWMAELGPWNYAIAFAFMITGLLLTMRWH
>NZ_AP022587.1|WP_163791407.1|4005467_4005893_+|PH-domain-containing-protein
MQQTQWEPRAAGVAGCGLGGLFMAIASVTLVTDPPGRVLVGIAGAGLLLFAGATWRARPKLAITPTGLVMRGWFQTQVLQHDDIKIIRITEFRRFGRRVRFLEVETAGDSLVLFSRWDLGTEPLEVLDALTDAGYAGRNDA

Crispr_ID: NZ_AP022587_3

• CRISPR_ID: NZ_AP022587_3
• CRISPR_location: 5982221-5982318
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_AP022587_3

Consensus_repeat	Method
CACTGCGGCCGGCTTACCCCCAC	CRISPRCasFinder

spacers of NZ_AP022587_3

>3.1|5982244|52|NZ_AP022587|CRISPRCasFinder
CGACCGCTAAGTCCCGCATGGCAACCCACGCCGTCGGGTACATGGCGACCGT

CRISPR arrays and Neighbor proteins around NZ_AP022587_3

CRISPR arrays

The CRISPR arrays of NZ_AP022587_3

>merge|NZ_AP022587|3|5982221-5982318|CRISPRCasFinder
CACTGCGGCCGGCTTACCCCCACCGACCGCTAAGTCCCGCATGGCAACCCACGCCGTCGGGTACATGGCGACCGTCGCTGCGGCCGGCTTACCCCCAC

>NZ_AP022587|3|3|5982221-5982318|CRISPRCasFinder
CACTGCGGCCGGCTTACCCCCAC	CGACCGCTAAGTCCCGCATGGCAACCCACGCCGTCGGGTACATGGCGACCGT
CGCTGCGGCCGGCTTACCCCCAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP022587.1|WP_163793999.1|5976008_5976332_+|WhiB-family-transcriptional-regulator	unknown	unknown	gnl|CDD|376791
NZ_AP022587.1|WP_163794001.1|5976728_5977379_+|GAP-family-protein	unknown	unknown	gnl|CDD|378566
NZ_AP022587.1|WP_163793988.1|5969538_5970192_+|FCD-domain-containing-protein	unknown	unknown	gnl|CDD|224715
NZ_AP022587.1|WP_163794005.1|5979417_5980860_+|PE-domain-containing-protein	unknown	unknown	gnl|CDD|376422
NZ_AP022587.1|WP_163794003.1|5977908_5979183_+|Nramp-family-divalent-metal-transporter	unknown	unknown	gnl|CDD|234815
NZ_AP022587.1|WP_163793990.1|5970210_5970831_-|sensor-domain-containing-protein	unknown	unknown	gnl|CDD|372884
NZ_AP022587.1|WP_163794022.1|5990333_5990984_+|HAD-IA-family-hydrolase	unknown	unknown	gnl|CDD|319829
NZ_AP022587.1|WP_163794026.1|5991291_5991396_+|hypothetical-protein	unknown	unknown	unknown
NZ_AP022587.1|WP_163794016.1|5986792_5987440_+|TetR-family-transcriptional-regulator-C-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|224228
NZ_AP022587.1|WP_163793996.1|5973271_5973946_-|NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|224995
NZ_AP022587.1|WP_163794013.1|5986432_5986765_+|hypothetical-protein	unknown	unknown	unknown
NZ_AP022587.1|WP_163794011.1|5985656_5986208_-|redoxin-domain-containing-protein	unknown	unknown	gnl|CDD|376354
NZ_AP022587.1|WP_163794018.1|5987681_5988995_+|NtaA/DmoA-family-FMN-dependent-monooxygenase	unknown	unknown	gnl|CDD|274819
NZ_AP022587.1|WP_163793994.1|5972960_5973269_-|NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|224995
NZ_AP022587.1|WP_163793998.1|5975047_5975707_+|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224715
NZ_AP022587.1|WP_170313077.1|5982735_5983494_-|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|224169
NZ_AP022587.1|WP_163794020.1|5988999_5989926_-|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|369777
NZ_AP022587.1|WP_163794009.1|5984462_5985623_-|NADH:flavin-oxidoreductase	unknown	unknown	gnl|CDD|239201
NZ_AP022587.1|WP_163794024.1|5991069_5991225_+|DoxX-family-protein	unknown	unknown	unknown
NZ_AP022587.1|WP_163793992.1|5972360_5972816_-|cupin-domain-containing-protein	unknown	unknown	gnl|CDD|380340

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_AP022587.1|WP_163793999.1|5976008_5976332_+|WhiB-family-transcriptional-regulator	gnl|CDD|376791	pfam02467, Whib, Transcription factor WhiB. WhiB is a putative transcription factor in Actinobacteria, required for differentiation and sporulation.	4.19001e-22
NZ_AP022587.1|WP_163794001.1|5976728_5977379_+|GAP-family-protein	gnl|CDD|378566	pfam11139, SfLAP, Sap, sulfolipid-1-addressing protein. SAP is a transmembrane transport protein with six predicted transmembrane helices, with a hydrophilic domain between helices 3 and 4. This hyrodphobic region is highly variable among identified Gap-like (GPL, peptidoglycolipid, addressing protein) proteins and may be involved in substrate recognition. SAP also belongs to the LysE protein superfamily (pfam01810), whose members have been implicated in small molecule transport in bacteria. Other Gap proteins export metabolites across the cell membrane so it is possible that Sap specifically may be involved in transport of sulfolipid-1 across the membrane.	5.3061e-37
NZ_AP022587.1|WP_163793988.1|5969538_5970192_+|FCD-domain-containing-protein	gnl|CDD|224715	COG1802, GntR, Transcriptional regulators [Transcription].	1.43694e-40
NZ_AP022587.1|WP_163794005.1|5979417_5980860_+|PE-domain-containing-protein	gnl|CDD|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	2.05643e-25
NZ_AP022587.1|WP_163794003.1|5977908_5979183_+|Nramp-family-divalent-metal-transporter	gnl|CDD|234815	PRK00701, PRK00701, divalent metal cation transporter MntH.	1.08631e-164
NZ_AP022587.1|WP_163793990.1|5970210_5970831_-|sensor-domain-containing-protein	gnl|CDD|372884	pfam14032, PknH_C, PknH-like extracellular domain. This domain is functionally uncharacterized. It is found as the periplasmic domain of the bacterial protein kinase PknH. The domain is also found in isolation in numerous proteins, for example the lipoproteins lpqQ, lprH, lppH and lpqA from M. tuberculosis. This family of proteins is found in bacteria. Proteins in this family are typically between 214 and 268 amino acids in length. There are two completely conserved C residues that are likely to form a disulphide bond. A second pair of cysteines are less well conserved probably form a second disulphide bond. It seems likely that this domain functions to bind some as yet unknown ligand.	1.51945e-20
NZ_AP022587.1|WP_163794022.1|5990333_5990984_+|HAD-IA-family-hydrolase	gnl|CDD|319829	cd07527, HAD_ScGPP-like, subfamily of beta-phosphoglucomutase-like family, similar to Saccharomyces cerevisiae DL-glycerol-3-phosphate phosphatase (GPP1p/ Rhr2p and GPP2p/HOR2p) and 2-deoxyglucose-6-phosphate phosphatase (DOG1p and DOG2p). This subfamily includes Saccharomyces cerevisiae DL-glycerol-3-phosphate phosphatase (GPP1p/ Rhr2p and GPP2p/HOR2p) and 2-deoxyglucose-6-phosphate phosphatase (DOG1p and DOG2p). GPP1p and GPP2p are involved in glycerol biosynthesis, GPP1 is induced in response to both anaerobic and hyperosmotic stress, GPP2 is induced in response to hyperosmotic or oxidative stress, and during diauxic shift; overexpression of DOG1 or DOG2 confers 2-deoxyglucose resistance. These belong to the beta-phosphoglucomutase-like family whose other members include Lactococcus lactis beta-PGM, a mutase which catalyzes the interconversion of beta-D-glucose 1-phosphate (G1P) and D-glucose 6-phosphate (G6P), and Escherichia coli 6-phosphogluconate phosphatase YieH. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	9.18209e-70
NZ_AP022587.1|WP_163794016.1|5986792_5987440_+|TetR-family-transcriptional-regulator-C-terminal-domain-containing-protein	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	8.82104e-10
NZ_AP022587.1|WP_163793996.1|5973271_5973946_-|NAD(P)-dependent-oxidoreductase	gnl|CDD|224995	COG2084, MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism].	1.78666e-18
NZ_AP022587.1|WP_163794011.1|5985656_5986208_-|redoxin-domain-containing-protein	gnl|CDD|376354	pfam00578, AhpC-TSA, AhpC/TSA family. This family contains proteins related to alkyl hydroperoxide reductase (AhpC) and thiol specific antioxidant (TSA).	1.57504e-23
NZ_AP022587.1|WP_163794018.1|5987681_5988995_+|NtaA/DmoA-family-FMN-dependent-monooxygenase	gnl|CDD|274819	TIGR03860, FMN_nitrolo, FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family. This model represents a distinctive clade, in which all characterized members are FMN-binding, within the larger family of luciferase-like monooxygenases (LLM), among which there are both FMN- and F420-binding enzymes. A well-characterized member is nitrilotriacetate monooxygenase from Aminobacter aminovorans (Chelatobacter heintzii), where nitrilotriacetate is a chelating agent used in detergents. [Unknown function, Enzymes of unknown specificity].	4.32563e-175
NZ_AP022587.1|WP_163793994.1|5972960_5973269_-|NAD(P)-dependent-oxidoreductase	gnl|CDD|224995	COG2084, MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism].	1.68609e-06
NZ_AP022587.1|WP_163793998.1|5975047_5975707_+|GntR-family-transcriptional-regulator	gnl|CDD|224715	COG1802, GntR, Transcriptional regulators [Transcription].	2.63601e-33
NZ_AP022587.1|WP_170313077.1|5982735_5983494_-|FAD-dependent-oxidoreductase	gnl|CDD|224169	COG1249, Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes [Energy production and conversion].	8.28443e-44
NZ_AP022587.1|WP_163794020.1|5988999_5989926_-|methyltransferase-domain-containing-protein	gnl|CDD|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	5.88653e-08
NZ_AP022587.1|WP_163794009.1|5984462_5985623_-|NADH:flavin-oxidoreductase	gnl|CDD|239201	cd02803, OYE_like_FMN_family, Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Members of OYE family include trimethylamine dehydrogenase, 2,4-dienoyl-CoA reductase, enoate reductase, pentaerythriol tetranitrate reductase, xenobiotic reductase, and morphinone reductase.	3.11086e-110
NZ_AP022587.1|WP_163793992.1|5972360_5972816_-|cupin-domain-containing-protein	gnl|CDD|380340	cd02210, cupin_BLR2406-like, Bradyrhizobium japonicum BLR2406 and related proteins, cupin domain. This family includes bacterial and fungal proteins homologous to BLR2406, a Bradyrhizobium japonicum protein of unknown function with a cupin beta barrel domain. Proteins in this subfamily appear to align closest to RmlC carbohydrate epimerase which is involved in dTDP-L-rhamnose production, and belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	6.45596e-37

Protein sequences

>NZ_AP022587.1|WP_163794005.1|5979417_5980860_+|PE-domain-containing-protein
MSVMTVVPEVLTAARGELSGIGALIVDANRAAAAPTLGVVAPAADCVSEQVAVLFGGHAASYQSFSAHAGVFHQEFVRTLTAVGADYAQTEAANAAPLSQGTILPPRARPTTDRQFVDTRWHPAAAMTSRLGRPGAGDKRPIVSGAAAASNRSTLTRPGLLNHAAISRELGTPHNDLRGGILNGTRGVVQQIIQNQINYLKTIATALQTFLHDEIAAIEALPAAFKQAFQDLFAGHIKQSMNDVLRGFAHLFIDGMQWDGQQVASGGSAIFPSRAWMEAVFTGPLTDLAPIWQIPEQELQHTADLLKPLGLGILGNTVQNLADALKAWNDGWHVYFGQDVEGAGLKIGAPLALMFDVLGAPALATRALEDGLQATLDTLVAGHPLKAMLDFVATPAKVMRAFLFGQGYLELPPFAAKGVEYDGAVHLGGIFAPLGLGKEQVTQLWDGQWAEVTDPNRGTYTGGIVAALWSMMMGALRGLL
>NZ_AP022587.1|WP_163794003.1|5977908_5979183_+|Nramp-family-divalent-metal-transporter
MTVTHQYGGVALADVQRRGRARTAFALVGPAFVASVAYVDPGNFATNFAAGGGYGYELVWVVVMANLMAILVQYLAAKVGIATGQNLAELCRRHYNRWTNVGLWLQAEIVAMATDLSEFVGAAVGLNLVFGLPLLPAGVVTAGAAFAILSLQQRGYRRFELVIIAMVAFVAIGFLYVFLAVGHQHYGQLVAGLVPQMTDRESVGLAVSIVGATVMPHVVYLHSALHINRVHAVTLEDRRILLRFNKWDCIIGLGSAGVVNLAMLCVAAALFHRPGLTNINDLGSVHAHLATLLGEGVALAFAIALLAAGLSSSSVGTYAGQVVMGGFMNWRIPLMVRRALTVLPALIILALTANTTQVLVLSQIVLSFGIPFALIPLILLSRRTDVMAQMVSRKITTTLTSVITAVITCLNAYLLYTTFAGWMS
>NZ_AP022587.1|WP_163794001.1|5976728_5977379_+|GAP-family-protein
MLIRLIPPALMIAISPITVIPAILVIHAPRPRPAGLAFLGGWLVGLTGLTVFFGVTCGVLEHLQTSPPVWVSWLRMLSGSAIIAFATWRWLTRHRRSDTPSWMRPFATLTPVRAAVTAVALAPLRLEVLIMCAYAGLTIGTGGIGAINGWLHGAVFVAVAGSTVAIPILAYIGAGDRLGQELTALKGWMERHHAALEGSILVLVGVLLCFKGIRGL
>NZ_AP022587.1|WP_163793999.1|5976008_5976332_+|WhiB-family-transcriptional-regulator
MAGQPGTRQPTTSNSPAPRSTGVDGETWESEGLCRNAHPDALFVAKARQRRAAKICNGCPVLRQCAAHALDNKVEYGVWGGMTEHRRQTLLKQHPYVLSWAELLSRC
>NZ_AP022587.1|WP_163793998.1|5975047_5975707_+|GntR-family-transcriptional-regulator
MSRVSRQTGVDLARDTLRNMILRGEITAGQRLTLTDVADRIGTSVTPVREALRDLAATGLVDVDARKGARVHAPTTDDITEIYELRMMLEVRAMTEVAALEEERRVVAAIMAGKVATQMDDEHDVADWAALNLDFHVHLTDPLRETWPVLYCLIESLRNRSMLSVATALRAKPALMQQANRDHRKLVTAIRNGDTDGAERVTTQYLGRTLKVLLKSYSG
>NZ_AP022587.1|WP_163793996.1|5973271_5973946_-|NAD(P)-dependent-oxidoreductase
MIWPRKTKDAAKLVAPPWHKDEVAAPIPGALATVAVPERLSVAVLGMEPLGTAVALRLVHAGFSPIGFDARPGKAARAVARGIVMAGGLAQAASVATVAIAVLPSAEALLQLSAQLRQCPDRQIRYVIDLSSLSTCTKICAADALQAIGITLLDCSVIGTSAQIYDGDVLVCASGPKPAIEHLRPVLAGFSRRVEEVGELGAATKMKAITSHLGMLHNAAPQKR
>NZ_AP022587.1|WP_163793994.1|5972960_5973269_-|NAD(P)-dependent-oxidoreductase
MAERIGLDPQQVWRLVTSEGTIADQLELRGALIASRMYGPSSATVSDCITELRQITELAQSVQSPTPLLDMAAVLYDVAASMGYGHHDSSAVHASYVQLPHP
>NZ_AP022587.1|WP_163793992.1|5972360_5972816_-|cupin-domain-containing-protein
MTNPDGFHPDFTASDRDTPRKRVHHIKASELDPGTAQTEGMRRFAAISGKSVGALNLWMGEVHVAAATASGNHHHGESETAIYIRSGHPEFVFHDGDQEVRIATAPGDYIFVPPYVPHREENPDPTTPAEVVIARTTQEAIVVNLPALYAL
>NZ_AP022587.1|WP_163793990.1|5970210_5970831_-|sensor-domain-containing-protein
MMLGNGALSGIFDQPFRLGRLPAPQVGGPEVLRTDAVPGPPDCLGVARMLERNVYQSTGVRNVAVETWKPSTRRAFVLDVEEGVVSVASPRDAQTLFDTFAEQWHRCDDARQSFRVGETKVDATITNVDVAPAILAATVRMHFPTLDLDADPIYTVRALGVRGNCLVEVKVEYSRRFKPTHPKPGEMNTSAVTIARAMMYNISALP
>NZ_AP022587.1|WP_163793988.1|5969538_5970192_+|FCD-domain-containing-protein
MAAKDGSSASARAYQHLRDRIVSGSIASGEMLSENDIAQSLEMSRTPVRLALVQLQHEGWVRIYPKRGALVRGLSDDDVRQLLQARLVLETGGVLDLSQQDRTELGVTLKQIVDEEAAAVDAGDWARFATLSLQFHRAFVAAGGNTYLTDFYDQIRDRQAVLLNQSQSVNEPRAAELIDEHRSLAAAVERDDRQALLERLRMHLDDAYGGDSEHRSA
>NZ_AP022587.1|WP_170313077.1|5982735_5983494_-|FAD-dependent-oxidoreductase
MDIRTRVSVAELHRSGGAGPVRVLLDSGDEIEVDEILFATGRIPNTEDIGLQSVGLIPGAWIDVDDRCLVRGVDGQWLYALGDANHRALLTHQGMYQARIAGAALGARAHGKALDTAPWGRHVTTADNLAVPQTFFTDPEAGSVGLTVAQAHKGGYRFTTVDVDMGQSVPGANLYADGYAGRARMLVDQDEGYILGVTMVGPGVTELLHSATVAVAGRLTIARLWHAVPCFPTISEVWLRLLEGYRDGAGVR
>NZ_AP022587.1|WP_163794009.1|5984462_5985623_-|NADH:flavin-oxidoreductase
MSLQQRARYESLFRPTAIGGVDLTNRVALAPMTRISATAEGVPTDRIGTYYRVFADGGFALLITEGLYIDDQTSQGYLFQPGIANHVQAEAWRRVVAGVHASGSKFFAQLMHAGSQAQGNPRTTVTWGPSAVRPKGEQLAMYRGSGPFQMPQAMTGDQISQVRAAFVSAARLARDVGFDGVEIHGANGYLLDAFITDYMNTRTDDYGGSLANRVRLATEVCGDVAAAVGTDIAVGIRISQGKVSDNHHRWVGGEDDAAAIFTALADTGIDYIHTTEYRALAPAFDGTETPLAKLAKQYSGLSIIANGHLDDPRDAASIIDSGAADVVALAKPALANRDWPRRVQTGKPLSPDLPVDLFGPVADIKDWEVADTSKSPADPQSHEIGG
>NZ_AP022587.1|WP_163794011.1|5985656_5986208_-|redoxin-domain-containing-protein
MSRLNYGQLFPALDFPAVGGGTISLPGDLAGSYGVILIYRGSWCPYCNAQLAAFSRALDSLSELNVKVVALSVDDEDTSAALVAKRKLRFPVGHNADADKVAIATGAYVNDDPHYLQSTGFILAPDGTVCLAVYSSGAIGRLVPDDVVGFIRYLTDASGDAISNTEQPHVTRPDGRGTAEQPR
>NZ_AP022587.1|WP_163794013.1|5986432_5986765_+|hypothetical-protein
MHGLALLAALNGIAKQYLSEDIGIRCAFRTARKPQPTVVGLAGEYCAGFQIDPSSQAPCTSMIVGLGDSRFVRVPISSGWTSKFVTVPRRFAAQAAIVQRLDHHASEKLD
>NZ_AP022587.1|WP_163794016.1|5986792_5987440_+|TetR-family-transcriptional-regulator-C-terminal-domain-containing-protein
MAPKEGRPTARLTIRGAATKARIVDGAASLVREHGVAGTSLDAVMTATGTSRSQRYHYFDNKDALIGEVIKTQFGRIIAAQEPLLRELSSWAGLQRWCDHLVAMVRETQGVGGCPLGSLVSELADRSESARQELARSFAEWQSYLSTGFATMRDNGELATEADVDDLALTMMSALQGGLLMAQTTRSARPLELALNMALGHVAGYRPSTMEPPPR
>NZ_AP022587.1|WP_163794018.1|5987681_5988995_+|NtaA/DmoA-family-FMN-dependent-monooxygenase
MSTRPLHFNAFIWPNGYHEAAWRVVDGDVRDVLGLSYYTDIARVAERGLMDSIFLADNIAIAEYRATYLPQTQFDPIAVLSAQAAVTDHIGLIGTGSTTYSKPWELARRFSTLDHLSGGRAGWNIVTTVTPLAAAAFGEPFHPENADRYAQAHEFVDAVTQVWDSWEDDAVVGDRERGVWADRAKLHAPRFHGKYYDVEGVQPFPRSPQGHPVLLQAGQSAAGVGLAARYAEVVFSGSPSLEAAIAFRANLHEQAAAIGRKADQIKVLPALMITLGSTEAEARARAQRLEDLENPEFRWQNTLYTAGLDPDGFDPDAPLPAELWAERSAPSSRAEQLFAVSRAEPEATLREIAQQVTGGLAGQTHFVGTPEQLADHVIAWQDEGAVDGFTIMGSTLPHELTAFVDHVVPILQRRGRFRTEYAGPTLRDQLGLERPAK
>NZ_AP022587.1|WP_163794020.1|5988999_5989926_-|methyltransferase-domain-containing-protein
MSTATKRAQYDFIYETLQHEPTALDFTISVLEKSYKSHFSKHASDVSGLLEDACKHLLAAGNGRELYQVSKEVHEQFFTSEGNGSWFSEGYSAYKSQRKPVQDFNNLADAISGSTVLDFGCGRGHLAALIAQAGFDCYTTDVMDYRGTNASHLPFRQMASPVDVPYADDMFNSAIVKTVLHHVDEPDLIPLLINLRRVARRLIIEEDTYAVPEESVGAATRQIELTEFNKLDESDQFRALVLIDFFGNAVAQGLVDMNFGCQFKKVSEWHSLFNSLGFRVVDTDVVGFRPGNIHKACQVRFVVDREEL
>NZ_AP022587.1|WP_163794022.1|5990333_5990984_+|HAD-IA-family-hydrolase
MAVLRGKRILFDIDGTLVDSTATVERSWGTWATEYGVDYDEVLKVCHGRRTEDTVAQFVAPQRRAAATARLLALQESADLDGVLALPGARRLLDALPPSHWAAVTSGPRSLMAARLAAARLPAPTLLIGAEDVSIGKPDPESYLKAAAALGFEAQECLVVEDAPAGVGAGRAAGAQVLAVSTTHHADELADADIVVTDLSCVSVEVTDSGVALLVI
>NZ_AP022587.1|WP_163794024.1|5991069_5991225_+|DoxX-family-protein
MGLVFAASGAIKLVVPKKRLALRGSSWVDDFSSGTVIFVGLTEIAGGLAML
>NZ_AP022587.1|WP_163794026.1|5991291_5991396_+|hypothetical-protein
MLGAAVVHARRREPGMIMLNLALLALAALAIWDR

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_AP022587_1	1.1|2130995|30|NZ_AP022587|CRISPRCasFinder	2130995-2131024	30	NZ_CP027859	Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence	1125011-1125040	7	0.767
NZ_AP022587_1	1.1|2130995|30|NZ_AP022587|CRISPRCasFinder	2130995-2131024	30	NZ_CP032054	Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence	726741-726770	7	0.767
NZ_AP022587_1	1.1|2130995|30|NZ_AP022587|CRISPRCasFinder	2130995-2131024	30	NZ_CP016560	Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence	383997-384026	7	0.767
NZ_AP022587_1	1.1|2130995|30|NZ_AP022587|CRISPRCasFinder	2130995-2131024	30	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	1825869-1825898	8	0.733
NZ_AP022587_1	1.1|2130995|30|NZ_AP022587|CRISPRCasFinder	2130995-2131024	30	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	929740-929769	8	0.733
NZ_AP022587_1	1.1|2130995|30|NZ_AP022587|CRISPRCasFinder	2130995-2131024	30	EU100883	Thermus phage P23-45, complete genome	16061-16090	9	0.7
NZ_AP022587_1	1.1|2130995|30|NZ_AP022587|CRISPRCasFinder	2130995-2131024	30	NC_009804	Thermus phage P74-26, complete genome	15298-15327	9	0.7

1. spacer 1.1|2130995|30|NZ_AP022587|CRISPRCasFinder matches to NZ_CP027859 (Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence) position: , mismatch: 7, identity: 0.767

tcccccgggcggagcctcgccaggcggaac	CRISPR spacer
ggccccgggcggagcttcgccgggccgccc	Protospacer
  *************.*****.*** *  *

2. spacer 1.1|2130995|30|NZ_AP022587|CRISPRCasFinder matches to NZ_CP032054 (Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence) position: , mismatch: 7, identity: 0.767

tcccccgggcggagcctcgccaggcggaac	CRISPR spacer
ggccccgggcggagcttcgccgggccgccc	Protospacer
  *************.*****.*** *  *

3. spacer 1.1|2130995|30|NZ_AP022587|CRISPRCasFinder matches to NZ_CP016560 (Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence) position: , mismatch: 7, identity: 0.767

tcccccgggcggagcctcgccaggcggaac	CRISPR spacer
ggccccgggcggagcttcgccgggccgccc	Protospacer
  *************.*****.*** *  *

4. spacer 1.1|2130995|30|NZ_AP022587|CRISPRCasFinder matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 8, identity: 0.733

tcccccgggcggagcctcgccaggcggaac	CRISPR spacer
acgcccgggcgcagccgcgccaggcgccct	Protospacer
 * ******** **** *********   .

5. spacer 1.1|2130995|30|NZ_AP022587|CRISPRCasFinder matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.733

tcccccgggcggagcctcgccaggcggaac	CRISPR spacer
tcccgcgggcggagccgcgccagccatcct	Protospacer
**** *********** ****** *.   .

6. spacer 1.1|2130995|30|NZ_AP022587|CRISPRCasFinder matches to EU100883 (Thermus phage P23-45, complete genome) position: , mismatch: 9, identity: 0.7

tcccccgggcggagcctcgccaggcggaac	CRISPR spacer
tagaagcggcggagcctcgcgaggcggaga	Protospacer
*      ************* *******. 

7. spacer 1.1|2130995|30|NZ_AP022587|CRISPRCasFinder matches to NC_009804 (Thermus phage P74-26, complete genome) position: , mismatch: 9, identity: 0.7

tcccccgggcggagcctcgccaggcggaac	CRISPR spacer
tggaagcggcggagcctcgcgaggcggaga	Protospacer
*      ************* *******. 

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	1218056 : 1227686	8	Shahe_endorna-like_virus(42.86%)	NA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_AP022587|1218056:1227686|DBSCAN-SWA
GATGAAATTCGTCCTGGCAAGCTACGGAACGCGCGGCGATATCGAGCCTTCGGCCGCCGTCGGCCGCGAACTGCAGAGCAGAGGGCACGACGTGGCGCTGGCGGTCCCGCCCGGGCTGCTGGACTTCACCGAGGCCGCCGGGCTTGCGGCCGTGTCCTACGGGCCGCCGATCGAGGAGTTCCTGGACGAGGACTTCCTGCGCAACATGTGGACGGATTTCTTCCGCAGCGCCTGGACGATCACCGGCCCGATCAAACTGGTGCGCAAGATCTGGGAGCCCATCATCGTGCACTGGGCCCAGGTTAATACGACGCTGATGTCGCTGGCAGACGGGGCCGACTTGCTGTCCACCGGCATCAATTTCGAACAGCCCGCAGCCAATGTGGCTGAACACTACGACATTCCGTTGGCCACGCTGCATCACTTCCCGATGCGGGCGAACGGCCAGCTGGCGCCGACCATGCCGGCACCGCTGGTCCGTTCCTCGATGATCGCGATCGAATGGCTGTTTTGGCTCTCGACGAAGAAGGTCGACAACGAACAGCGCCGCGAACTCGGCCTGCCGACCGCGACAGCTCGCTCACAGCGACGCATCGCCGACCGGGGTTCCCTGGAAATCCAGGGCTACGACGACGTGTGCTTTCCCGGGCTGACCGCCGAGTGGGCGAAATGGGGCGACCGCAGGCCCTTTGTCGGTGCGCTGACAATGGAATTGACCACCGACGCCGACGAGGGCGTCACGTCGTGGATCGCCGCGGGAACACCCCCGATCTGCTTCGGCTCGGGCAGCATCCCGGTCGAATCCCCGACGGAATTGGTGGAGATGATCGGCGCGACGTGCGCGGAATTGGGTGAGCGAGCACTGGTGTGCTTCGGCGGGACGGACTTCACCGACGTGCCGCATCCCGAGCACGTCAAACTGGTGGGTCCGGTGAACTACGCAACGGTCTTCCCCGCCTGCCGCGCGGTGGTTCACCATGGCGGCTCGGGCACCACAGCCGCCAGCATGCGCGCGGGGATCCCCACGCTGATCCTGTGGAGCTCGGCCGACCAGCCGTACTGGGGAGCTCAGGTGAAACGGTTGAAGGTCGGCGCAGCGCGGCGCTTTTCGACGGCCACGCAGGAGACGTTGGTCACGGATCTACGCGAGATCCTGGCCCCCCAGTACGCCGGTCGCGCCCGCGAACTCGCGACGCGGATGACCAAACCCGCCGAAAGCATCGGCCGCGCCGCCGATCTCCTCGAAGAGGCCGCCCGCGGCAAAGGCTGAGCGGGTCACTGTACCGGCTTGATCAGCAGGCCCTGCCCGGTGGGCAGCGCGCAGATCGCCACGCCGAATTCGGCTGCCAAGGCGTCCATGGCGGCACGCTGCTCGTCGCGCCCCCGATTCGCGTAATCGTCGAGGAGCACAAAGGCGCCCGGCGTGAGTCGCGGCCAGAAATGGCGCAGCGCGGCGATTTCGGGTGGCGCACAGTTCATGTCGATGTGCAGGTAAGCCACCGACTGCGACTCGACCTGGTCGAGGGTTTCGGGAACCGCACCGACGATGATGCGCACGTTTTTCCACTCTGCGAAATTCGCGCGGACACCCTCGACTCCGCTGACGTACATCCCGTTGCGCAGCTTGGTCTGGCTTCGCTCAAACTCCCCGGATTCGCGTTCGTGGTCTGTGACGAAGCGCGAATCGATGCCTGCGAAGGTGTCGAGCAAATAGAACGTCTTGCCCAGCCGATCCCAGTCGAGGTGCTCCATGATGGCGCTGCTCAAGAACCCATAACTGACGCCGCACTCCACGAAATCGCCGTCCAGTCGGCTGGCGCTCTTTGCCGCCCACAGCCCGACGTGCACCCGCCACTGCCACTGGTACCAGTCCTGGTCGGGCAGCGCCTGCGCACCGCGTTTGTAGGCCCGCTGGAACGCGGGGTCGTCCAGGAATGCGTCGTTGTGAAAGCTGATCAGGCCATCGCTTGCGTAGACATCGGGCAGCACGGTGCGGGCGAGCCAATACTCACCGCGCACCCACCACATCAGCAGGCGTGTCTTGACGTGTAGACCGTTTGCCACGGCGGCAACCATAACATTGGCGCCCACCGTGCCTCCGGTGAATGGGATGGGTCCACGGCCAACGTGGTTGACCGAACGCGCGACACCCGGTGCGGCAAACATGTTCGGAGGCATGGGTTTACAGCGAACGACGTTCGCCGTCCGTGCTTTTGGGAACCGGCTCCAGATGCTACGGCCGTGTGGTGGTCATGGCTTGCGCCACAGCACGCCGGTGCCGTCGATTTCCTCGATCTCGGCGGTTATTCCGTGCTTCTCGCGGTAGTCAGCCACCGCCTGCTCACACGCTTTCAGGGCGTGATAGTCGTCGATAATGCAATAGCCGCCCGACGACAACCGTGGGTAGAGCGCATCGAGGGCCTGGATCGTCGATTCGTAGAGGTCGCCGTCAAGGCGTAGCACCGCGATCTGCCCGATCGGGGCGTCGGCCAATGTGTCCTTGAACCAGCCCGGTACAAAATCTACCTGGTCATCGAGTAACCCGTAACGCTCGAAATTCGCCTTGACCTGCTCTTGCGAGACCCCAAGAATGCTCGCGTGGCGGTGCAGCTTAATCCCTTTATCCGCTTTGTAATTCGCGGCGTCCGGCGGAGGTACGCCGGCAAACGAATCGGCGAGCCACACCTTGCGCGTCCGATCTCCGTAGGCCGAAAGGACCGCACGCATCAAAATCGAGGCGCCGCCGCGCCACACGCCACACTCGACCAGGTCACCGGGAACGTCATCGGCCAGCACCGTCTCCACACACTGTTGCAGGCTGGTCAGCCGCTGCATCCCGATCATGGTCAACGCGTCCGCCGGCCAATCCAGGCCCCGGTCCCGCGCGTACGCGTTGAACGGGTACTTGCGCACGAGCATGAAATTCCGGGCGTTGAAAATGGGCCGCCCCAGCCGATACCACCCGACCGGCACCAGCTCGTCTTGACCGTATCGAGTGAGGTCACGTCGGAGCAGATCGAGATACGCGGACCGCGCGTCGAGATCAGTCACGGTCAAAACGGCCTTCTCCTCGCATGCCATTACATCCAATCCTGGAGCCTAAGCGCCCCAACTCCCCGCTCGATCAGTCATCCCGATCCCGCATTACCAATCCAGGGCTCGAGATGCCGTCCATACCAACCCCCAAAGCATGTTAGCTGAGTGCCCGACGCATGACTCCCGAATCGAGGTGCTGAAGGGCGAATCGGCGGCGCCTAGCCTCGCCCGCCGATCACGCAAAACGTCCGTTATGCGCGAAACTTTCCAGCAGGTCGGCAGCGCGGCTGACGCTGTCGTTGGCCTGCGTCATCTGAGTGGCCAGTGCGCGCGCTTTGGCAGCGCATTCCGGAGTGAGGATCTGCCGCAGATCCTCGATCAACGTCTCCTTGGTGGTGAGCGAAAACTTGCGGGCTGCACCGACTTTCAGTCGTTTGAGATGACCTCCCCAGAATGGCTGATCGCCTGCCGTCCAGAGAATCAGGGTGGGGATACCGGCGCGCAGGCCCGCGGCGGTGGTGCCCGAACCGCCGTGGTGCACCACCGCGCGGCAGTGTGGGAAGACCTTCGCGTAATTCACTGCACCGACCACCCTGACGTGATCGAAATGCGGCACCTCGCTGAAGTCGGCCCAACCGGCGCAGACCAATGCCCGCTCGCCCAATTGCTCGCAGGCCGACGCGATCATCTCGACCGTATCGGTCGGGGTTTCGCTGACCGGCATGCTGCCAAAGCCAAAGACGATCGGCGGTGTTCCGGCGTCCGCCCATGCCGCGACCTCGTCGTCGATGTCCGTCGTCAAGCCCATCGTCAGCGCGCCGACAAAGGGCCGTCGCTCGCCCCATTTCGCCCATTCGCGCGCCAGGCCCGGGAAACACACCGCGTCGTAGGCCTGTAGCTCCAACGATCCGCGTTTGGCGATCCGTTGCGGGGAGGCACACGTGGTCTTGGGCAGGCCGAGCTTGCGGCGCTGGGCATCCTCGGCCTTCTTGTTCATCCGCCAGACCATCCAGTCGTACGCCGCCATGCCGGTGCGGACCAGCGGCGCCGGCAGATTCGGGATGAGCTGCCCGTTGGGCCGCATCGGGATGTAGTGCAGTACAGCCATCGGGATGTCGTAGTACTCCGCGACGTTCGTCGCGAGGTCCTGGTACAGCTGGCCGGTAAAGAGTACGTCGGCCCCGGCGGTCAGCGCGGTCAGGGTCTCGCTCATGTCCGTCCAGGACCGCAACACGGGCTCCCAGGCTTCGCGCACCAGCTCGATCGGGCCGCGGATGGACCAGAATGTGCGACGGAACCTCGACCAGAAGTTGCGCAGGAACTCGTCGTCCCAGAACGCCTGCATATCCGGTCCATACGCAACCGCGTCAAGGCCGGCCGTCTCGGCGAGGCCAAGCAGGTTAGGCGGGATGGCCATCCGAACTTCGTGGCCTCGACGCAGCAGTTCGCGCCCCGCGGCGAGAGAGGGCTCGACATCCCCCCGGGTTCCATAACATGCCAGAACAAATTTCATCGCGAGGCAAGACCTATCACTTCCCGTCGGCCTAAGCAAGCCCGCTCTGGCGCATTTATCATCGCTTCACACCCTTCTTTCAGCATCCGGGGCCGAACCGAAATTCGCTATCGCCGCGGACACATCGGTGTTCGTAGGCAGCGAGCAACTCTCGACCATCAGAGCATGTGATCGGAAGACCAAAGGTGGTCTGCCGATTTAATATTCGACAACGCAAACGCCTGGCAAATCTTCGGATATAGCGAACTCGAGACATGTTTGCCGACGGTCGCTGCACAATTGGCGGCGAGCCACGTTCGCCGGTTAAGCAAAATGCTTCGCACGAGCGAACTCTTCGACCAGATCGGCCGCGGTACTGACACTCTCGGCGGGCTTGGTCATCCGGATGGCGAGCTCACGGGCCCTCGTCGCGTATTCCGGGACCAGGATCTGGCGCAGGTCAGTGAGCAGCGACGCGCGGGTGGTGTTCGAAAAGCGCCGGGTGGTGCCCACTTTCAGCCGTTTGAGCTGCGCCCCCCAGATCGTCTGGTTCGGGTCCATCGAGAGGATCAACGTGGGAACGCCCGCGCGCATGCTGGCGGCCGTCGTTCCCGAGCCGCCGTGGTGCACGACGGCACGGCAGGCGGGAAAGACCTTCGCGTAGTTCACGGCCCCTACCACCTTGACATGGTCGAGGTGCGAGACGCCGCTGAAATCGCTCCAGCCGGCGCACACCAATGCCCGCTCACCCAGCTCCGCGCAGGCCGCGCTGATCATCTCGATGGTCTCGGCCGGCGATTCCACCGGCATGCTGCCGAAACCAAAGCAAATGGGCGGTGTGCCCGCGGCAATCCATGCTGCCACGTCGTCATCGACGTCGGTGGTCAGCTCCATCGTCAGCGTGCCGACAAACGGGCGTTGGCCGTCCCATTTCGCCCATTCGGCCGCCAGCCCGGGAAAGCACGCTTCGTCGTAACCCTGGATCTCCAGGGATTGCCGTTTCGCGATCCGGCCCGGGGACGGGCCGGATGCCTTCGGCAGGCCGAGTTCACTGCGCTGCGTGTCCTCGACCTTCTTGTTCAGCCGCCAGCAGAACCAGTCGAACAAGACCATTGAGTAGCGCGCCAGCGGTGGTGGCAGGAACGACACGACTTGGCCGTTGGGCCGCATCGGGACGTGATGCAGCGTGGCCAGCGGAAGGTCGTAATACTCCGCGACATTGGCGGCGGGTTCCTGGTAGCTCAGCCCCGCGAACAACAGGTCGGCGTCTTCGGCCAGCGACACCAGTGTCGTGTTCATCTGCGACCAGCACTCGTCGCTAAGGTCCCACATCTCGCGCCACAACCGTCTTAGCTGCCGGACCCGCCAGAACCTGCTGAAGAAAGTCGTCCAGAGGTTGCGGTAGACGTCCAGCCAGGTCCGCGTGTCCAGTCCGTAGGAGACCGCCGGAAGGCCCGCCGCCTCGACGAATTCCATCAGGTCGGGCGCGACGGCCATCCGCACGTCGTGGCCCCTGCGCTGCAGTTCGCGCGCCACCACGAGGGAGGGCTCGACATCGCCTCGAGTTCCGTAGTTAGCCAGCACGAATTTCATTGCGAACTCAGGCCTTAGGTCGTTATGGCTTGCGCCAGAGCACGCCGGTGCCGTCGATTTCCTCGATCTCGGCGGTTATTCCGTGCTTCTCGCGGTAGTCAGCCACCGCCTGCTCACACGCCTTCAGGGCGTGATAGTCGTCGATAATGCAATAGCCACCCGACGACAATCGCGGATAAAGGGCGTCCAGTGCCTGGATCGTCGATTCGTACAGATCGCCATCGAGCCGCAACACCGCAATTTGCTGGACCGGAGCGTCAGCTAACGTGTGCTTGAACCAGCCGGGGATAAAGCGAACCTGGTCATCAAGCAGACTGTAGCGCTCGAAATTCGCCCTGACTTCCGCCTCCGGCACGCCCAATATTTTCGCGTGACGGTGCAGCTTAATCCCTTTATCCGCTTTGTAATTCACAGTATCGGGCGGTGGCACTCCGGCAAACGAATCAGCCAGCCACACGGTTCGCGTGTGGTCTCCGTAAACCGAAAGGACCGCACGCATCAAAATCGAAGCGCCGCCGCGCCACACGCCACACTCGACCAGGTCGCCCGGCACGCCGTCGGTCAGCACCGTCTCGACGCAATTCTGCAGGCTGGTCAGCCGCTGCATGCCTATCATTGTCAGGGCGTCAGTCGGCCAATCCAGGCCCAAATCCCGCGCATGCTGGTCAAAGGGATATTTACGCACCAGCATAAAATTGCGGGTATTGAAAACGGGCCGCCCCAGGCGATACCACCCGACGGGCACCAGCTGATCCTGGCCGTATCGGGTGAGGTCACGACGGAGCAGGTCGAGATACGCCGAACGCGAATCAGTTTCAGTCGCGGTCAAAACTGCCCCCTACTTGCCATGCCTCTACTCCCATGTGTCAACCGGTTGTTCAGCCTAGACGTCCACCGACGCCGCCAATGCATTTCGCGGTTTTCCCTCGAGCCTCCGGCGCCACCTGACCTCAGCACGACGCGTGACTTCACGGGATCGGCGCCCCAGAACGTTCCTGCGCCGACGCCACGGCCAGTCGAACCTGCCGGGCCCCGACGGCGTGTGGCACTCTACCGCCAATTGCGGTCAAGCTAACGCATCCGGTCGAGCTTACCCAGTCCGGTGATCTCGAGACTCACCGACTTCCGCGACCCGGCCACCCCCAGCAGGAAAAGCACGTCTCCTATCGGGGCGCCCAGCCAAAATCGCCAGAACGGCTTTCGCAAGAACTTCACGGCGAAGCTACCCTCCCCAATCAGCCAATACACCGGGACCGCGACCATGCGGTAGAAGATGCGCTTCCATCGCGCGGAAACCATCTCGAGATTCATCTCCATCATCTCGAGGCCCCAAGCGCGGTACTGCCATTCCAATTCGTAGCGTGACTGAAACTGGAAGAAGGCCCGCATTTCACCATTGGTGACGAGATACTCGTCGAAGACGAGGATCGAACCCGGAACGAACCGTTCCTTGCACGTTTCCAACGCGTGCAGGCAACTCTCGTAGGTGTCCAGATCCATATGAAACAACCTGATCGGCGCATTCGGCCGCTCGGCGAGAAACGGGGCCAGCGTGTCGTAGGTGCTTCCCTTGATGAACTGGACTTTACGACCGAGGGCGTCGGGCAGCCCCTCGTGGAAATTCACGCCGGTATCGTGCATAAAGCGCTGCGCGAACGGATCTGACAAAGAAAACGTTCCGCGTTTGACGACATGGTCCTCGAGTTTCCAGTCCTCCACGAGACCCTCGAAGCTGTCGAAACCGTAAACCATCCGGCCGCTCGCATCCGATATCAGCCTTGTCGACCATCCGATCCAGACACCGAGGTCGAGGATTAATTCGTCGGAGTCCCCCAGAGATGGCCCGGCCAAACCCGAGGCCTCCGACAACAACGTGTGGTCTCGGATTCGGCGCAGACGCAAATCCTCCATGGTCTTATGAATGAACTCGCGATAGGCGTCGTCATAGATCTTGGTGTCACGGGCATACAGGTTGGGAATGAAGCGATCCCGCCCCGGATAAACGATGCGTGCGCCTAGGAGCAACACCAGGATTGCGCCGATTGCGATGAGCAGGGCCGGCTCGAAGTAGCATGCCGCAGCCACGACGAGCGCAATCCCGATGAGGACCGCTTTCCACAGACGATGAACTGCCGTCCGCTCCACTGCCCGCCTGTCCACCACAACGCCCACCGGTTCACCTCCCTGTCCTGGCTACATTAGGGCGAATCACCCAAAGTTAATGAATGAATCACACGATTGCCTAATAAGTCACCCTGGGCTGTACAGCGAACTCGACTTCACGGCGGCGCGCCCCCGGCCCGGCGGACCTTTCCCACGTGGTCACAAGTGACGGCGTGACGCGTGCCCAGTCGTTGCACGCCAAGCTGTTCGACGTGCGGCCATCGGCTAGTTCCGACCGGCATGTTCTGCTATCGAACGGTTCGATTCGCGCCCGTGATCGGTTGCCGCGGAAGCGGATTCCCGCTGCCGTTCGATCCATTCCAGCAGTTTTCGCAAACCGTCGTCGAGCGTCCACTTCGGGCGCCAGTCCAGCACTTCTTGGGCAGGCTCGATATCGCAACTCGCCGCCCGCACGTCGCCATCGCGGAATTTCGATACCACGACCGGTTCGGGGGCCCGGCAAACGGCGCTGATCGTTTGTGCCAGCTGATGAATCGTGGTCGGGGTGCCCGATCCGATGTCGAGACAGCGTTGTTCGATCGCGGGTTGCTGCACCGAGGCGAACAGCGCGTCGACCACTTCGTCGATATACACGAAATCGCGCACGATCCGGCCGTCCTCGTAAACTTCCAGCGAATGCTGCTCGCGGGCCAGCCGGGCGAAGAGTGCCACGATTCCGGTGTACGAATTGGTCAGCGACTGGCCCGGCCCATACACGTTCTGCAGGCGCAGCACACTCACATTCGTGTCGTGCGCGGCGGTCCAGGCTGCCAAGGTGTGCTCCTGGGCAAGCTTTGTCGCCGCGTAGACGTTGGTGGGCCGGGGCTCGGTTCGGCCCGCGCGGCTCGGCAGGGGCACCGCGGGTTCACCCGTGGGGCCCTGCGGATCCCAGTTGCCCGCCACCAGCTGAGCGTGGCTGCGCGGCCGCGGGTAGAAGACCTGCCCGCCGCATTCCCAGGCGCCCTCGCCGTAGACGGCCCTCGACGACGCCAGCACCAGCTGATCGGGGACGATTCCCGCGCGGCTCAACGCATCGAGAAGCTGGGTGGTGCCGACAACGTTGACCGAGCCGTGCCGCGTCGCCTCCGAGAGCGATTGCGCCGTTCCCGTCTCGGCGGCCAAATGCACGATCTGCGAAGGACGGAACAACCGAAGCACCGCATCCCAGTCGGGTGCGTGGGTGACGTCGCCGGTGAACAATCGCACGGACGACGGCAGATCGATCGCCTGCCCTGCGGCGTGCACCTGGGGGTGCAGAACATCCATCACAGCGACGTCGTAACCGGCTTTGACCAGGCGGCGCGACAGCGCCGACCCGATGAATCCAGCTCCACCGGTGATAAGCAC

Protein sequences of DBSCAN-SWA_1

>NZ_AP022587|1218056:1227686|1225247_1226261_-|WP_163794537.1|DBSCAN-SWA
MAAACYFEPALLIAIGAILVLLLGARIVYPGRDRFIPNLYARDTKIYDDAYREFIHKTMEDLRLRRIRDHTLLSEASGLAGPSLGDSDELILDLGVWIGWSTRLISDASGRMVYGFDSFEGLVEDWKLEDHVVKRGTFSLSDPFAQRFMHDTGVNFHEGLPDALGRKVQFIKGSTYDTLAPFLAERPNAPIRLFHMDLDTYESCLHALETCKERFVPGSILVFDEYLVTNGEMRAFFQFQSRYELEWQYRAWGLEMMEMNLEMVSARWKRIFYRMVAVPVYWLIGEGSFAVKFLRKPFWRFWLGAPIGDVLFLLGVAGSRKSVSLEITGLGKLDRMR
>NZ_AP022587|1218056:1227686|1220305_1221112_-|WP_163788937.1|DBSCAN-SWA
MTVTDLDARSAYLDLLRRDLTRYGQDELVPVGWYRLGRPIFNARNFMLVRKYPFNAYARDRGLDWPADALTMIGMQRLTSLQQCVETVLADDVPGDLVECGVWRGGASILMRAVLSAYGDRTRKVWLADSFAGVPPPDAANYKADKGIKLHRHASILGVSQEQVKANFERYGLLDDQVDFVPGWFKDTLADAPIGQIAVLRLDGDLYESTIQALDALYPRLSSGGYCIIDDYHALKACEQAVADYREKHGITAEIEEIDGTGVLWRKP
>NZ_AP022587|1218056:1227686|1224198_1225005_-|WP_163788940.1|DBSCAN-SWA
MTATETDSRSAYLDLLRRDLTRYGQDQLVPVGWYRLGRPVFNTRNFMLVRKYPFDQHARDLGLDWPTDALTMIGMQRLTSLQNCVETVLTDGVPGDLVECGVWRGGASILMRAVLSVYGDHTRTVWLADSFAGVPPPDTVNYKADKGIKLHRHAKILGVPEAEVRANFERYSLLDDQVRFIPGWFKHTLADAPVQQIAVLRLDGDLYESTIQALDALYPRLSSGGYCIIDDYHALKACEQAVADYREKHGITAEIEEIDGTGVLWRKP
>NZ_AP022587|1218056:1227686|1222907_1224176_-|WP_163788939.1|DBSCAN-SWA
MKFVLANYGTRGDVEPSLVVARELQRRGHDVRMAVAPDLMEFVEAAGLPAVSYGLDTRTWLDVYRNLWTTFFSRFWRVRQLRRLWREMWDLSDECWSQMNTTLVSLAEDADLLFAGLSYQEPAANVAEYYDLPLATLHHVPMRPNGQVVSFLPPPLARYSMVLFDWFCWRLNKKVEDTQRSELGLPKASGPSPGRIAKRQSLEIQGYDEACFPGLAAEWAKWDGQRPFVGTLTMELTTDVDDDVAAWIAAGTPPICFGFGSMPVESPAETIEMISAACAELGERALVCAGWSDFSGVSHLDHVKVVGAVNYAKVFPACRAVVHHGGSGTTAASMRAGVPTLILSMDPNQTIWGAQLKRLKVGTTRRFSNTTRASLLTDLRQILVPEYATRARELAIRMTKPAESVSTAADLVEEFARAKHFA
>NZ_AP022587|1218056:1227686|1226564_1227686_-|WP_163794538.1|DBSCAN-SWA
MLITGGAGFIGSALSRRLVKAGYDVAVMDVLHPQVHAAGQAIDLPSSVRLFTGDVTHAPDWDAVLRLFRPSQIVHLAAETGTAQSLSEATRHGSVNVVGTTQLLDALSRAGIVPDQLVLASSRAVYGEGAWECGGQVFYPRPRSHAQLVAGNWDPQGPTGEPAVPLPSRAGRTEPRPTNVYAATKLAQEHTLAAWTAAHDTNVSVLRLQNVYGPGQSLTNSYTGIVALFARLAREQHSLEVYEDGRIVRDFVYIDEVVDALFASVQQPAIEQRCLDIGSGTPTTIHQLAQTISAVCRAPEPVVVSKFRDGDVRAASCDIEPAQEVLDWRPKWTLDDGLRKLLEWIERQRESASAATDHGRESNRSIAEHAGRN
>NZ_AP022587|1218056:1227686|1221326_1222604_-|WP_163788938.1|DBSCAN-SWA
MKFVLACYGTRGDVEPSLAAGRELLRRGHEVRMAIPPNLLGLAETAGLDAVAYGPDMQAFWDDEFLRNFWSRFRRTFWSIRGPIELVREAWEPVLRSWTDMSETLTALTAGADVLFTGQLYQDLATNVAEYYDIPMAVLHYIPMRPNGQLIPNLPAPLVRTGMAAYDWMVWRMNKKAEDAQRRKLGLPKTTCASPQRIAKRGSLELQAYDAVCFPGLAREWAKWGERRPFVGALTMGLTTDIDDEVAAWADAGTPPIVFGFGSMPVSETPTDTVEMIASACEQLGERALVCAGWADFSEVPHFDHVRVVGAVNYAKVFPHCRAVVHHGGSGTTAAGLRAGIPTLILWTAGDQPFWGGHLKRLKVGAARKFSLTTKETLIEDLRQILTPECAAKARALATQMTQANDSVSRAADLLESFAHNGRFA
>NZ_AP022587|1218056:1227686|1219330_1220083_-|WP_163794536.1|DBSCAN-SWA
MWWVRGEYWLARTVLPDVYASDGLISFHNDAFLDDPAFQRAYKRGAQALPDQDWYQWQWRVHVGLWAAKSASRLDGDFVECGVSYGFLSSAIMEHLDWDRLGKTFYLLDTFAGIDSRFVTDHERESGEFERSQTKLRNGMYVSGVEGVRANFAEWKNVRIIVGAVPETLDQVESQSVAYLHIDMNCAPPEIAALRHFWPRLTPGAFVLLDDYANRGRDEQRAAMDALAAEFGVAICALPTGQGLLIKPVQ
>NZ_AP022587|1218056:1227686|1218056_1219325_+|WP_163788936.1|DBSCAN-SWA
MKFVLASYGTRGDIEPSAAVGRELQSRGHDVALAVPPGLLDFTEAAGLAAVSYGPPIEEFLDEDFLRNMWTDFFRSAWTITGPIKLVRKIWEPIIVHWAQVNTTLMSLADGADLLSTGINFEQPAANVAEHYDIPLATLHHFPMRANGQLAPTMPAPLVRSSMIAIEWLFWLSTKKVDNEQRRELGLPTATARSQRRIADRGSLEIQGYDDVCFPGLTAEWAKWGDRRPFVGALTMELTTDADEGVTSWIAAGTPPICFGSGSIPVESPTELVEMIGATCAELGERALVCFGGTDFTDVPHPEHVKLVGPVNYATVFPACRAVVHHGGSGTTAASMRAGIPTLILWSSADQPYWGAQVKRLKVGAARRFSTATQETLVTDLREILAPQYAGRARELATRMTKPAESIGRAADLLEEAARGKG

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_163788936.1|1218056_1219325_+	glycosyltransferase	A0A1L3KK54	Shahe_endorna-like_virus	2.5e-06	40.3
WP_163794536.1|1219330_1220083_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_163788937.1|1220305_1221112_-	class I SAM-dependent methyltransferase	A0A2R8FDY2	Brazilian_cedratvirus	7.8e-54	51.0
WP_163788938.1|1221326_1222604_-	glycosyltransferase	A0A1L3KK54	Shahe_endorna-like_virus	3.0e-07	41.9
WP_163788939.1|1222907_1224176_-	glycosyltransferase	A0A1L3KK54	Shahe_endorna-like_virus	1.9e-06	39.7
WP_163788940.1|1224198_1225005_-	class I SAM-dependent methyltransferase	A0A2R8FDY2	Brazilian_cedratvirus	1.9e-52	50.2
WP_163794537.1|1225247_1226261_-	class I SAM-dependent methyltransferase	A0A2H4PE59	Mycobacterium_phage	1.9e-12	33.0
WP_163794538.1|1226564_1227686_-	NAD-dependent epimerase/dehydratase family protein	L7RCI0	Acanthamoeba_polyphaga_moumouvirus	1.3e-17	24.9