CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP048925	Lactobacillus plantarum strain X7022 plasmid unnamed4, complete sequence	0 crisprs	NA	0	0	0	0
NZ_CP048923	Lactobacillus plantarum strain X7022 plasmid unnamed2, complete sequence	0 crisprs	NA	0	0	0	0
NZ_CP048924	Lactobacillus plantarum strain X7022 plasmid unnamed3, complete sequence	0 crisprs	NA	0	0	0	0
NZ_CP048922	Lactobacillus plantarum strain X7022 plasmid unnamed1, complete sequence	0 crisprs	csa3	0	0	0	0
NZ_CP048921	Lactobacillus plantarum strain X7022 chromosome, complete genome	1 crisprs	csa3,cas9,cas1,cas2,csn2,DinG,cas3,DEDDh	1	11	6	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP048921_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP048921_1

115069-116226

TypeII

Consensus_repeat	Method
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	PILER-CR
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CRISPRCasFinder
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CRT

17 spacers

csn2,cas2,cas1,cas9,csa3

The CRISPR arrays of NZ_CP048921_1

>merge|NZ_CP048921|1|115069-116226|PILER-CR,CRISPRCasFinder,CRT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACGACGATCGGGCTGATAACCTAATCTGGTCAGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACGAATCGAAAGCAAGAATGCTGACGAATATCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACCTCAACCGCAGCTTTGATAGCTCCTTCGGAGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACCTCAACTCGAGGTCGCGTAGATTGTCCAGTGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACCAGTAGCTCCAACAGGAACAGTAAAATTGTGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACTGGAAGTTACCAACATCTAATTCGCGATGTGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACCCGATCACCCACTAGCAATAGGGCCAGAACGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACAGACATGGCAAAGTGACGACTAGAACCATTGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACCTAGTACCTGTTGAATCAAAACGATCAGCAGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACAAATTATTGTTAAAATTAGGTTATTCAATTGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACCCTTACTAATTAATCCGGCTCCGATGGAACGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACTTGGAACAAAGAAAGAAGTTAAAGCATTACGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACATGTATGGTTGCTGAACCCCATTTGCCGCTGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACAGTGGTGTACTCATAGTCTTTTCCCTCCATGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACTTCAGCAGCTGGGTCCACGCCTGAAATCGTGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACGGTATGGAGTACAACAAGGAACAAGACACGGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACGATGCTGAGGAAACGAAGCATAGAACGTTTGTCTTGAATAGCGGCCACATCAAAAACAGTTTCACG

>NZ_CP048921|1|1|115069-116160|PILER-CR
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GACGATCGGGCTGATAACCTAATCTGGTCA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GAATCGAAAGCAAGAATGCTGACGAATATC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CTCAACCGCAGCTTTGATAGCTCCTTCGGA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CTCAACTCGAGGTCGCGTAGATTGTCCAGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CAGTAGCTCCAACAGGAACAGTAAAATTGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TGGAAGTTACCAACATCTAATTCGCGATGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CCGATCACCCACTAGCAATAGGGCCAGAAC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AGACATGGCAAAGTGACGACTAGAACCATT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CTAGTACCTGTTGAATCAAAACGATCAGCA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AAATTATTGTTAAAATTAGGTTATTCAATT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CCTTACTAATTAATCCGGCTCCGATGGAAC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TTGGAACAAAGAAAGAAGTTAAAGCATTAC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	ATGTATGGTTGCTGAACCCCATTTGCCGCT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AGTGGTGTACTCATAGTCTTTTCCCTCCAT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TTCAGCAGCTGGGTCCACGCCTGAAATCGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GGTATGGAGTACAACAAGGAACAAGACACG
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC

>NZ_CP048921|1|1|115069-116160|CRISPRCasFinder
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GACGATCGGGCTGATAACCTAATCTGGTCA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GAATCGAAAGCAAGAATGCTGACGAATATC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CTCAACCGCAGCTTTGATAGCTCCTTCGGA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CTCAACTCGAGGTCGCGTAGATTGTCCAGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CAGTAGCTCCAACAGGAACAGTAAAATTGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TGGAAGTTACCAACATCTAATTCGCGATGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CCGATCACCCACTAGCAATAGGGCCAGAAC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AGACATGGCAAAGTGACGACTAGAACCATT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CTAGTACCTGTTGAATCAAAACGATCAGCA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AAATTATTGTTAAAATTAGGTTATTCAATT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CCTTACTAATTAATCCGGCTCCGATGGAAC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TTGGAACAAAGAAAGAAGTTAAAGCATTAC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	ATGTATGGTTGCTGAACCCCATTTGCCGCT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AGTGGTGTACTCATAGTCTTTTCCCTCCAT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TTCAGCAGCTGGGTCCACGCCTGAAATCGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GGTATGGAGTACAACAAGGAACAAGACACG
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC

>NZ_CP048921|1|1|115069-116226|CRT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GACGATCGGGCTGATAACCTAATCTGGTCA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GAATCGAAAGCAAGAATGCTGACGAATATC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CTCAACCGCAGCTTTGATAGCTCCTTCGGA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CTCAACTCGAGGTCGCGTAGATTGTCCAGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CAGTAGCTCCAACAGGAACAGTAAAATTGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TGGAAGTTACCAACATCTAATTCGCGATGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CCGATCACCCACTAGCAATAGGGCCAGAAC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AGACATGGCAAAGTGACGACTAGAACCATT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CTAGTACCTGTTGAATCAAAACGATCAGCA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AAATTATTGTTAAAATTAGGTTATTCAATT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CCTTACTAATTAATCCGGCTCCGATGGAAC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TTGGAACAAAGAAAGAAGTTAAAGCATTAC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	ATGTATGGTTGCTGAACCCCATTTGCCGCT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AGTGGTGTACTCATAGTCTTTTCCCTCCAT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TTCAGCAGCTGGGTCCACGCCTGAAATCGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GGTATGGAGTACAACAAGGAACAAGACACG
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GATGCTGAGGAAACGAAGCATAGAACGTTT
GTCTTGAATAGCGGCCACATCAAAAACAGTTTCACG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP048921.1\|WP_011100889.1\|102244_102985_+\|gamma-glutamyl-gamma-aminobutyrate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|224982
NZ_CP048921.1\|WP_054399478.1\|116290_119029_-\|cation-transporting-P-type-ATPase	unknown	unknown	gnl\|CDD\|319775
NZ_CP048921.1\|WP_011100893.1\|107840_108623_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP048921.1\|WP_070083201.1\|113181_114087_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NZ_CP048921.1\|WP_163626799.1\|119687_120290_-\|NAD(P)H-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|377026
NZ_CP048921.1\|WP_163626797.1\|108911_112988_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	mkCas0193_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|374653
NZ_CP048921.1\|WP_070083199.1\|107108_107816_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048921.1\|WP_071542797.1\|121984_122269_-\|LytTR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197918
NZ_CP048921.1\|WP_057137382.1\|103227_104820_+\|DNA-binding-protein	unknown	unknown	gnl\|CDD\|214906
NZ_CP048921.1\|WP_015379640.1\|114064_114370_+\|CRISPR-associated-endonuclease-Cas2	cas2	mkCas0206_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|226043
NZ_CP048921.1\|WP_003641730.1\|119427_119622_-\|PspC-domain-containing-protein	unknown	unknown	gnl\|CDD\|377200
NZ_CP048921.1\|WP_163626802.1\|124254_125448_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340897
NZ_CP048921.1\|WP_003641737.1\|123860_124190_+\|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
NZ_CP048921.1\|WP_003646323.1\|121532_121988_-\|DUF3021-domain-containing-protein	unknown	unknown	gnl\|CDD\|378668
NZ_CP048921.1\|WP_003643663.1\|122567_123800_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340949
NZ_CP048921.1\|WP_060684252.1\|114366_115044_+\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd12218_csn2_CAS-II-A	gnl\|CDD\|213411
NZ_CP048921.1\|WP_003641733.1\|121022_121445_+\|Hsp20/alpha-crystallin-family-protein	unknown	unknown	gnl\|CDD\|107228
NZ_CP048921.1\|WP_003641725.1\|105638_107003_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|182694
NZ_CP048921.1\|WP_163626800.1\|120403_120877_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_CP048921.1\|WP_163626795.1\|104935_105406_-\|NUDIX-hydrolase	unknown	unknown	gnl\|CDD\|240033

Protein	Function_ID	Function_description	E-value
NZ_CP048921.1\|WP_011100889.1\|102244_102985_+\|gamma-glutamyl-gamma-aminobutyrate-hydrolase-family-protein	gnl\|CDD\|224982	COG2071, COG2071, Predicted glutamine amidotransferases [General function prediction only].	7.45143e-88
NZ_CP048921.1\|WP_054399478.1\|116290_119029_-\|cation-transporting-P-type-ATPase	gnl\|CDD\|319775	cd02080, P-type_ATPase_cation, P-type cation-transporting ATPase similar to Exiguobacterium aurantiacum Mna, an Na(+)-ATPase, and Synechocystis sp. PCC 6803 PMA1, a putative Ca(2+)-ATPase. This subfamily includes the P-type Na(+)-ATPase of an alkaliphilic bacterium Exiguobacterium aurantiacum Mna and cyanobacterium Synechocystis sp. PCC 6803 PMA1, a cation-transporting ATPase which may translocate calcium. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_CP048921.1\|WP_011100893.1\|107840_108623_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	8.96404e-26
NZ_CP048921.1\|WP_070083201.1\|113181_114087_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	2.73131e-89
NZ_CP048921.1\|WP_163626799.1\|119687_120290_-\|NAD(P)H-dependent-oxidoreductase	gnl\|CDD\|377026	pfam03358, FMN_red, NADPH-dependent FMN reductase.	9.32641e-32
NZ_CP048921.1\|WP_163626797.1\|108911_112988_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|374653	pfam16592, Cas9_REC, REC lobe of CRISPR-associated endonuclease Cas9. The REC lobe of Cas9 - the CRISPR-associated endonuclease Cas9 - includes the REC1 and REC2 domains. REC1 forms an elongated, alpha-helical structure consisting of 25 alpha helices and two beta-sheets, whereas REC2 inserted within REC1 adopts a six-helix bundle structure. The REC lobe and the NUC lobe of Cas9 fold to present a positively charged groove at their interface which accommodates the negatively charged sgRNA:target DNA heteroduplex. CRISPR (clustered regularly interspaced short palindromic repeat)-Cas system occurs naturally in bacteria as a defense against invasion by phages or other mobile genetic elements. Cas9 is targeted to specific genomic locations by sgRNAs or single guide RNAs, in order to complex with invading DNA in order to cleave it and render it inactive.	3.90894e-129
NZ_CP048921.1\|WP_071542797.1\|121984_122269_-\|LytTR-family-transcriptional-regulator	gnl\|CDD\|197918	smart00850, LytTR, LytTr DNA-binding domain. This domain is found in a variety of bacterial transcriptional regulators. The domain binds to a specific DNA sequence pattern.	6.75435e-19
NZ_CP048921.1\|WP_057137382.1\|103227_104820_+\|DNA-binding-protein	gnl\|CDD\|214906	smart00910, HIRAN, The HIRAN protein (HIP116, Rad5p N-terminal) is found in the N-terminal regions of the SWI2/SNF2 proteins typified by HIP116 and Rad5p. HIRAN is found as a standalone protein in several bacteria and prophages, or fused to other catalytic domains, such as a nuclease of the restriction endonuclease fold and TDP1-like DNA phosphoesterases, in the eukaryotes. It has been predicted that this protein functions as a DNA-binding domain that probably recognises features associated with damaged DNA or stalled replication forks.	1.88552e-17
NZ_CP048921.1\|WP_015379640.1\|114064_114370_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	2.01798e-25
NZ_CP048921.1\|WP_003641730.1\|119427_119622_-\|PspC-domain-containing-protein	gnl\|CDD\|377200	pfam04024, PspC, PspC domain. This family includes Phage shock protein C (PspC) that is thought to be a transcriptional regulator. The presumed domain is 60 amino acid residues in length.	2.12668e-17
NZ_CP048921.1\|WP_163626802.1\|124254_125448_+\|MFS-transporter	gnl\|CDD\|340897	cd17339, MFS_NIMT_CynX_like, 2-nitroimidazole and cyanate transporters and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Escherichia coli 2-nitroimidazole transporter (NIMT) and cyanate transport protein CynX, and similar proteins. NIMT, also called YeaN, confers resistance to 2-nitroimidazole, the antibacterial and antifungal antibiotic, by mediating the active efflux of this compound. CynX is part of an active transport system that transports exogenous cyanate into E. coli cells. The NIMT/CynX-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.02195e-118
NZ_CP048921.1\|WP_003641737.1\|123860_124190_+\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.17836e-13
NZ_CP048921.1\|WP_003646323.1\|121532_121988_-\|DUF3021-domain-containing-protein	gnl\|CDD\|378668	pfam11457, DUF3021, Protein of unknown function (DUF3021). This is a bacterial family of uncharacterized proteins.	7.07627e-26
NZ_CP048921.1\|WP_003643663.1\|122567_123800_+\|MFS-transporter	gnl\|CDD\|340949	cd17391, MFS_MdtG_MDR_like, Multidrug resistance protein MdtG and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli multidrug resistance protein MdtG, Streptococcus pneumoniae multidrug resistance efflux pump PmrA, and similar multidrug resistance (MDR) transporters from bacteria. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtG confers resistance to fosfomycin and deoxycholate. PmrA serves as an efflux pump for various substrates and is associated with fluoroquinolone resistance. MdtG-like MDR transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	7.1962e-140
NZ_CP048921.1\|WP_060684252.1\|114366_115044_+\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213411	cd12218, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	2.57931e-80
NZ_CP048921.1\|WP_003641733.1\|121022_121445_+\|Hsp20/alpha-crystallin-family-protein	gnl\|CDD\|107228	cd06471, ACD_LpsHSP_like, Group of bacterial proteins containing an alpha crystallin domain (ACD) similar to Lactobacillus plantarum (Lp) small heat shock proteins (sHsp) HSP 18.5, HSP 18.55 and HSP 19.3. sHsps are molecular chaperones that suppress protein aggregation and protect against cell stress, and are generally active as large oligomers consisting of multiple subunits. Transcription of the genes encoding Lp HSP 18.5, 18.55 and 19.3 is regulated by a variety of stresses including heat, cold and ethanol. Early growing L. plantarum cells contain elevated levels of these mRNAs which rapidly fall of as the cells enter stationary phase. Also belonging to this group is Bifidobacterium breve (Bb) HSP20 and Oenococcus oenis (syn. Leuconostoc oenos) (Oo) HSP18. Transcription of the gene encoding BbHSP20 is strongly induced following heat or osmotic shock, and that of the gene encoding OoHSP18 following heat, ethanol or acid shock. OoHSP18 is peripherally associated with the cytoplasmic membrane.	2.47416e-43
NZ_CP048921.1\|WP_003641725.1\|105638_107003_+\|amino-acid-permease	gnl\|CDD\|182694	PRK10746, PRK10746, putative transport protein YifK; Provisional.	0
NZ_CP048921.1\|WP_163626800.1\|120403_120877_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	0.000140147
NZ_CP048921.1\|WP_163626795.1\|104935_105406_-\|NUDIX-hydrolase	gnl\|CDD\|240033	cd04677, Nudix_Hydrolase_18, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	5.38579e-58

>NZ_CP048921.1|WP_060684252.1|114366_115044_+|type-II-A-CRISPR-associated-protein-Csn2
MNITYYPFPPFKIDAGKVNVLDLGNSNMYAEVCQGFRDRIDSVRISNDDLELQTISSQCNWYGDLMLSVDLNRLFLKKVQTQIIKLMADDRQVAVLDENRKVVSQVMEASFLLDLPLDVDESPSLEQILKFTGIHFPTALMNDPRAILEALVQTHVELGLKQKLVLTNISHYLDQKQWASFEQLVHDLGATVIVIEYSEINRMEKFKNSCYYYVDEDLVDWRDMN
>NZ_CP048921.1|WP_015379640.1|114064_114370_+|CRISPR-associated-endonuclease-Cas2
MRLIVMFDVPMDTSEERRAYRHFHKALVREGFLMMQYSTYVRVCVNKKAAEFVEKRIAPLAPKGGKVQTMTVTEKQYQAMHYIQGTPSNDILNSAERTIVI
>NZ_CP048921.1|WP_070083201.1|113181_114087_+|type-II-CRISPR-associated-endonuclease-Cas1
MGWRNVIITQHAKVSYSMNRILVQTSSDKYAVPISDIQLLLVGTTQAVITSAALCALAEAHVKVIFTDHQGEPISETNDYYPTRRTADLVRQQVTWPEARIATLWTKNVGSKILNQIQVIDFVGGDTQTLVDELDKLELNDVTNREAVVANKYFSLLFGDQFYRRDFSPINAALNYGYAVLLSMVNREIVLNGYLTCIGIHHENNENEFNLGSDLMEPFRPIVDQWVSQQRFKDFTPDIKIGLVSLLDLEIGFNGHQTIVSHAITEYVAACLHYLSGETEELKIEVKLPNEVSSDAINSHV
>NZ_CP048921.1|WP_163626797.1|108911_112988_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MKEPYGVGLDIGTNSVGWTVVDASGHVRKIKGQTGIGVRLFKEGAAAADRRGFRTTRRRLKRVKWRLRLLREFFDQPISKVDINFFARRKYSDISPRDPNYNGLEKTLFNDRSDQDFYHDYPTIYHLREALMTQHRKFDVREIYLAIHHIVKYRGNFLRNDAATAYRSGTLDLQQHFETLNHLFSQADLELNLNLTTDVALLDSIKQTLVRTDISRSDRQKLIMPLLAVLTGATTAEKKRQKAVVTEFAKALVGNKTKIDVLTLTDIDATEAKDWAFSLEENQDKLPGIEDRFSEVGQQIIDEVIRLYASVNLAQLIPEGKRFSQSMVEKYKRHGEDLKLLKAYIRSQSDAKRGRAIRATYDQYIDGVKSKQVTQEAFQKALGKFVDADVDLNSWAAQIKQAIDSEQFMPKLRTKQNGAIPYQVQQNELDQIISNQKEYYPWLGEENPVIKRRGKFPYKLDELVGFRVPYYVGPLITKEMQAATANAGFAWMVRKADGPITPWNFDDKVDRVASATAFIQRMQTTDTYLIGEEVLPARSLIYQRFMVLNELNNIRVDDGQLTPRQKQRLYNQVFKKHKRVTAKNIQDNLVAAGEFPTAPRITGLADPKVFNSSLSTYHDLKQVLPEAMSDVRKQADIEKIILWSTIFEDSTIFKQKLTEISWLTAAQLKQLGQLRYRGWGQLSRKLLTGLKDDNNRSIMDGLWETNANFMQLRSQPAIENQIKSANQANLTTADLQDTINELYTSPQNKKAIREVMVVLADIKDAMHGQTPNWIFVEAARGGGVAGRRTQSRSKQIVAAYQGTAQAIVSDQVQRELKEKIKNKANFNTRLVLYFLQNGRDLYTGDAINIDRLSEYDIDHILPQSLVKDDSLDNRVLTNARINREKNDMFASEKFGKKMGAKWKEMHRMGLMTKRKLDHLLMRPDEISKYATGFINRQLVETRQVIKLVEELINAEYPSTAIVSVKANLTHQFRQTFDFPKIREVNDYHHAFDAALTAFIGTYLLKRYPKLERFFVYGKFAKQPVNLTRFNVIRKLAKTDTPITDIDTGEVLWDKLTDIKYFETLYDYKRLLVTREVSENYGAMFDQTLLKASDNGKRLIRKKQSFDTAIYGGYTGKTLAYMAIVKVSTKKDVQCQVVGVPTTMVTQIEQLEQQGMTNKQAVTKVIEPLIAANNKKMLTYEVLLPKVRFEQVVRDRIKGQTHRFALGTDTYYHNIQELYLPLTLQRAFLGKQNESEVQLNQNLLTVFDATLAQVNRYFPLYEMNKFKKILNSARDQIELLEAKNQFVKNKLVLGKQGILTNMFIGLHANASYGDLKVLGVKTDFGKLQVPGGIKLTGDAEIIYQSPTGLFERKIALKDL
>NZ_CP048921.1|WP_011100893.1|107840_108623_+|alpha/beta-hydrolase
MRFITSDHVQLDYTDEGQGQPIVILTGFGGAKDIWRAQIPVLIQAGYRVINLDGRCQGLSEHTAKGLRMSRRAVDAHELIEKLQLEQPILLGNSMGAATWFAYVSLYGDTGIKALIDVDQTPRMINTPHWQYGFKQVQWQDIPDYFRMPLGHSTFKHIDDATYARVKAVEAQAPFDAKLMFPLLVNHAVQDWRDVIRQLTVPFLIIAGAKSPFFNPDFAAVTAQMALRGQSVVIPEAGHIVMAEQSAAFNKALLEFLATC
>NZ_CP048921.1|WP_070083199.1|107108_107816_+|hypothetical-protein
MVKQGHYAKVSKQKRLRQLKQRRQAQEKRAIMPEMVSEFLQVRYHLTQAAKQQPAMRQMMQRFMAQWLAAGQAELSDNGQTTWSVVALTKQTLQTFNRQLPWQGYALVDQEMARWTAFLNKEVPAVPLSERITLTEALSPATWQACLSEQLAINALLALTGDSRQLGQITTEQVRQLQTSIQTATGIDWEKVAQLLDSTVIAQNTLSEAGLDDKTRQWLEKLKKLTPQDFNDHVE
>NZ_CP048921.1|WP_003641725.1|105638_107003_+|amino-acid-permease
MQRKLSTGQMQMIALGGTIGVGLFMGSSSTIKWTGPSVLIAYIVSGAFLYLIMRALGEMLYVDPNTGSFAKFASEYIHPVFGYLTAWSNIFQFVVVGMSEMIALGGYCRYWWPNLPDWIPGLIAIVFLCAANLISVKMFGTLETWFSLIKVVTIILMIIAGLGLIIFGIGNGGHPIGISNLWTHGGFFTGGVKGFVFALAIVLASYQGIELIGVTAGEAENPQSTIVKAIRSTVARILIFYVGAIFVIVSIYPWDKLSQIGSPFVQTFAKIGITAAASIINFVVITASLSGTNSGIYSASRMTYTLAESHQLPRKMTLLNRHGVPFYSVIAIATGILIGVVLNVVLPMFFKDASEIFVMVYSSSVLPGMVPWFVILVSQIAFRKQNAAKMANHPFKMPLSPYSNYLTLAFLALTLVFMFINPETRYSILVGVVFLVIMTLIYFRKYAGNKEETL
>NZ_CP048921.1|WP_163626795.1|104935_105406_-|NUDIX-hydrolase
MANYIKKIRALVGHKPIILNTAAGILVNDQQQVLLNLRTDTHNWSLPGGYLEYGETYATACLREYKEDSGIDVEVVDRIGIFDKGETAYPNGDVAQTISALFLVKPIGGHVLTQATDETLKLDYFDFDNLPPLLNQQNADMIHAAQEYLQTHSATK
>NZ_CP048921.1|WP_057137382.1|103227_104820_+|DNA-binding-protein
MERIEAGMSVMTLKKQTYRVIAVINQGQELLVRAHEPETADIEIIPVTTVVQVTEQNSTDDAAVALDTVTVVGERYVDDIVATLTTLRVGMAVLLQRESGNQYDDNAISVWTLQHAKLGYIARYQNQPYATLMDQGQRLYGIVTVLDQQKQHLELMLWRTTAVPSPIEALQIRQRLAKPRTNLGAVPTHSLQTPLGTIVMMCNGHPIKYQQVPLSPWLTPADELHVTKRYLLTPDWSQVPPDSLITCQVTAKADVVQRWQNEHISAAVLTNASSFYVVGISAQTKTGLNDNLVDDAAQPAVIYRVGQVSAHMQAGFMVSWAPFGDPRVQPALKLALHFSSQPLVPYHPVTPSRTNATFTQQELAALLVSALPNYQGGQRLEPSVTTITVEKLRQTLGDQTYHALANYQRHVQLVAGSTEGVNETLLQALIHAVTYHELTTMHYYQPTVGMVDQVIYPIQLFSTTTKDEDDAQLVGCLALYNYETFEIQQVPLTAIARIAIIADPEHPQTTPETESPDWLRIFLHGWNDGF
>NZ_CP048921.1|WP_011100889.1|102244_102985_+|gamma-glutamyl-gamma-aminobutyrate-hydrolase-family-protein
MVKPIIGIAPGVVTVNSQMFPGRVRDYVNRDYLKSVTDNGGVPLVLPVTTDATTIERYVGMIDGLLLCGGADVAPLTYGEEPQPKLGGVDPERDQYEIALIRATHAVGKPVLGICRGLQILNVCYGGNLYQDMSELPAGQGTLKHMQGQLAAYGMHHVKVVPGTTLAEYLGTTSDAIAINSFHHQAVKQVATGFQVVAQSADQVVEAIEATAGGLQLGVQWHPEMMQQVNSMQARLFAAFVRACVA
>NZ_CP048921.1|WP_054399478.1|116290_119029_-|cation-transporting-P-type-ATPase
MIKDDNQSLTSNEEQNDTQNPPDADNLWQLDESALAAKYATDPENGLSTAEAAERLQHNGRNELETKRTSRFVQFIKQFNNSIIYILAAAAVLTFFMHHYSDSIVIGLVIIANAIIGYVQERQAGNALERIREMLISKNFVIRDGKKLEIDARELVVGDLVNLEAGDAVPADMRLISADNFNVQESVLTGETNPVEKQEEPMTETTLALADRKNMVYASTAVTSGSAVGIVTATAEDTEIGHIQQSVSDVKQTTTPLMRNLNSLGVGLSIAIVVAAVLLFLLGMVMDTYSLPTLLIAVITMVVGSMPEGLPASTSVVLAMGTRQMTKKNVIVKSLPAVETLGAVDIVNTDKTGTLTKNEMTVTKVVTPEHTFDVTGVGYDDNGGVNFDGHLKLNGNKVDWHQDNAMEWLVKIAGQTTDAELHFENNRWELTGEPTDGALTTLYRKMTGHDPEVEEVDSLPFDSAFRFSARLADLDGQRLLMVKGSPATVLRLTDQANQTAYWDDAMDDLTADGLRVVALAYQEVDDDVTTIDAQAIGGLHLAGLVGIIDPPREEAATAIAELRQAGVQVKMITGDHPDTAMAIANKLNLAANVKAITGPEIDAMDDQQLQAHIDDYNVFARATPNNKLRIVRAQQANNHVVSMTGDGVNDAPALKQADIGVAMGIKGTEVAKESADMVLADDDFADIVAAVREGRHVFDNIRKTIRFLLPTSFAEGLVVIISILMGHELPLYPTQLLWINMVSALTIQFAFIFEPPEAGIMARGPRNVKSGLLSKLDYFEIGYVSFLISGLGIFAYDYLTALGLPNVVGSTMSLNIIIFGKIFYLFNLRNDHPVISKYFFQNKMAFYIIGILILLQLGIIYLPFMQSVFHTTSINFWYGWGIPIICGIVVLIVTEVGKFIRFRWMGKDGVID
>NZ_CP048921.1|WP_003641730.1|119427_119622_-|PspC-domain-containing-protein
MKIDIHRSATDRVIAGVIGGIAEHFNWNTNVTRLLFVVLAITPMFPGIIAYLILWLLMKDPIKD
>NZ_CP048921.1|WP_163626799.1|119687_120290_-|NAD(P)H-dependent-oxidoreductase
MFKIAIILGSTRSQANGRALFNHLKLIIDQLPTHSTIHYQFLDLANYQLPLFDEPEPPMANPHRELPANQQQWLTDMASADGYIILTPEYNHAMPAGLKNAFDFLTFEGARKPAKIISYSDNMRGGQFGAAALVPVLQRLGMVVLPKPTPIGNVPQTLQSNGHFIDNAPLSKRYDHALHQTLTEITYYTTVLTTTPFPTD
>NZ_CP048921.1|WP_163626800.1|120403_120877_+|MarR-family-transcriptional-regulator
MTTPLVSQLMTELNQFLTQDSVDDQEKRWAMQQTTDPQLQAALKQLSTTDIKIIAYLGRRGASRAKSLPAPTELSQATISRGLTKLSRLKLATKYRDLTNNKEILVRLTTLGEAVADLHTQLDAAIAAKAQDIADDYSDAELRRFVSLMRRIREIKI
>NZ_CP048921.1|WP_003641733.1|121022_121445_+|Hsp20/alpha-crystallin-family-protein
MANTLMNRNDFGMLDPFERMARSFWAPLENMDQVLKTDINETDDQYQVKVDVPGIDKQDVKLDYRDNVLSIKVQKDSFVDHEDQDQNIVMNERHTGTLQRQYMLPNVAADKITASQADGVLTITLPKTQPSANDGQIEIQ
>NZ_CP048921.1|WP_003646323.1|121532_121988_-|DUF3021-domain-containing-protein
MKRLWHTLLIGAIGGIVIGYLMALGFSTFFNTTYLFPSNPTFVSHWSSPLAATQLSTLLWILIGEVWAFSSWLFEIETWSITKQTIAHCLCSYLGMTPLAILCGWFPLNVRWFGFYTLVYTGAYIGLWLIEMALARIKVIQLNQQLTNHRS
>NZ_CP048921.1|WP_071542797.1|121984_122269_-|LytTR-family-transcriptional-regulator
MPLQSVSRFYTANKRLYCETTTGAYLVHSHLHTLMDQLPPHQFLRISSSEIVRIACVKNFTLTKWGSFQVNLTTGTTTYASRRYTQQIRKAAQL
>NZ_CP048921.1|WP_003643663.1|122567_123800_+|MFS-transporter
MDDAERERGPWHRNLIVLWFCTFVAGMAFSEIMPFLSLFVSQLGDFTKAQITFYSGLAFAADYAISAISAPLWGIIADKKGRKIMLLRASLGMAVAMGLMGFVTNVWQLVALRALQGVFAGFISNAQALVASQTPRKYSGRALSTLITGAVSGQLFGPVIGGLLAQLFSIRNTFFITAGLLMVAFLLSLFFVQEHFKPVAHHREPGDSRNPLAAFQNPRLIIVMLCSTAIVQFGNASIAPIISLYVRELMHYRGPITVVAGIIAALPGISNIFSAPRLGRYGDQHGSGKVLLFGYIFAVIMYFPQGIVTSVVALGILRFAIGISDGALYPEIQTVLTKNTPVHLTSTIFSYNQSFQAIGNMFGALLGGLVAGWFNYNAVFIMTALLLLINLGLILWLVPDIWKNGKRAVS
>NZ_CP048921.1|WP_003641737.1|123860_124190_+|winged-helix-turn-helix-transcriptional-regulator
MMLIQCIVSFMNIEISKQDQADQQRVAIFKALADANRLRIIRVLYQAQREMTCSEVGAQLNISKSTVSYHFKTLRLVGLTNTRRKAQTKYLSLQLATFDRFLPGFLATL
>NZ_CP048921.1|WP_163626802.1|124254_125448_+|MFS-transporter
MTTTHQHSRYLTLGMMLAATNMRLPITMMPGLISSLKRTLGLPSSMAGLLTTIPLLTFAIMSPLIAHWGRRFGNELTIYVMLIFLAVGSYLRVIPTIAALFIGTLLVGIGADGGNVLIPAIIKDNFPTKIPVATSQYTLSMLLVGSLGTGLSGVLAAHWSLPLTMAVLSVIGLINLVVWLPNLKYNHRAPTVTMTASDGQSTATHGSVWRRPLAWVVTAFFGLQALVYYSLLTWLPTVFVAHGFSLIVAGNLVTVMQLSGLPMSYLVPATSGHRRGVWAMIMVVGVGFIAGIGGILLSGTNFWLAALSCVLLGLGSGAAFSLAVVFFTQKTTNGFETADLSGMAQSAGYLLAAVGPVLFGWLGGQLGWGPVLWLAIILSALLALSGSIIFQHATIYE

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP048921_1	1.9\|115633\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115633-115662	30	NZ_CP048921.1	1370297-1370326	2	0.933

1. spacer 1.9|115633|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to position: 1370297-1370326, mismatch: 2, identity: 0.933

ctagtacctgttgaatcaaaacgatcagca	CRISPR spacer
ctagtacctgttgaatcaaaacaatcaaca	Protospacer
**********************.****.**

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP048921_1	1.14\|115963\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115963-115992	30	MG788324	Lactobacillus phage PM411, complete genome	36757-36786	0	1.0
NZ_CP048921_1	1.14\|115963\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115963-115992	30	NZ_CP024415	Lactobacillus plantarum strain ATCC 8014 plasmid pLP39, complete sequence	12992-13021	1	0.967
NZ_CP048921_1	1.14\|115963\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115963-115992	30	NZ_CP018210	Lactobacillus plantarum strain BLS41 plasmid pLPBLS41_1, complete sequence	31561-31590	1	0.967
NZ_CP048921_1	1.4\|115303\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115303-115332	30	NC_004305	Lactobacillus phage phig1e, complete genome	28301-28330	3	0.9
NZ_CP048921_1	1.4\|115303\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115303-115332	30	X98106	Lactobacillus bacteriophage phig1e complete genomic DNA	28301-28330	3	0.9
NZ_CP048921_1	1.10\|115699\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115699-115728	30	NC_047764	Lactobacillus phage P1, complete genome	68788-68817	3	0.9
NZ_CP048921_1	1.10\|115699\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115699-115728	30	KY381600	Lactobacillus phage P2, complete genome	72360-72389	3	0.9
NZ_CP048921_1	1.10\|115699\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115699-115728	30	MT074146	Bacteroides phage SJC03, complete genome	52059-52088	4	0.867
NZ_CP048921_1	1.10\|115699\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115699-115728	30	JX486088	Lactobacillus phage ATCC 8014-B2, complete genome	78404-78433	4	0.867
NZ_CP048921_1	1.9\|115633\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115633-115662	30	NZ_CP012653	Lactobacillus plantarum strain HFC8 isolate Lactobacillus plantarum plasmid pMK07, complete sequence	6483-6512	5	0.833
NZ_CP048921_1	1.10\|115699\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115699-115728	30	NC_047926	Lactobacillus phage Semele, complete genome	111784-111813	5	0.833
NZ_CP048921_1	1.12\|115831\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115831-115860	30	MK448975	Streptococcus phage Javan526, complete genome	1686-1715	5	0.833
NZ_CP048921_1	1.12\|115831\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115831-115860	30	MK448782	Streptococcus phage Javan501, complete genome	2025-2054	5	0.833
NZ_CP048921_1	1.12\|115831\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115831-115860	30	NC_022111	Prevotella sp. oral taxon 299 str. F0039 plasmid, complete sequence	1656530-1656559	5	0.833
NZ_CP048921_1	1.10\|115699\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115699-115728	30	NC_015427	Clostridium botulinum BKT015925 plasmid p4BKT015925, complete sequence	10031-10060	6	0.8
NZ_CP048921_1	1.12\|115831\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115831-115860	30	MT074138	Bacteroides phage DAC17, complete genome	25184-25213	6	0.8
NZ_CP048921_1	1.12\|115831\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115831-115860	30	MT074136	Bacteroides phage DAC15, complete genome	26175-26204	6	0.8
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NC_020841	Psychrobacter phage pOW20-A genomic sequence	39840-39869	7	0.767
NZ_CP048921_1	1.8\|115567\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115567-115596	30	NC_014628	Paenibacillus polymyxa SC2 plasmid pSC2, complete sequence	493258-493287	7	0.767
NZ_CP048921_1	1.9\|115633\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115633-115662	30	MF001355	Proteus phage PM2, partial genome	154194-154223	7	0.767
NZ_CP048921_1	1.10\|115699\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115699-115728	30	MK448925	Streptococcus phage Javan386, complete genome	11787-11816	7	0.767
NZ_CP048921_1	1.10\|115699\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115699-115728	30	MG557979	Lactobacillus phage Lpa804, complete genome	76149-76178	7	0.767
NZ_CP048921_1	1.12\|115831\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115831-115860	30	CP024687	Bacillus wiedmannii bv. thuringiensis strain FCC41 plasmid pFCC41-3-257K, complete sequence	36286-36315	7	0.767
NZ_CP048921_1	1.12\|115831\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115831-115860	30	NZ_CP015180	Bacillus thuringiensis serovar alesti strain BGSC 4C1 plasmid pBMB71, complete sequence	953-982	7	0.767
NZ_CP048921_1	1.12\|115831\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115831-115860	30	NC_020240	Bacillus thuringiensis serovar kurstaki str. HD73 plasmid pAW63, complete sequence	953-982	7	0.767
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP021940	Klebsiella pneumoniae strain AR_0145 plasmid tig00000209, complete sequence	52412-52441	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP012427	Klebsiella pneumoniae strain KP5 plasmid pSg1-1, complete sequence	98303-98332	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP044034	Klebsiella pneumoniae strain FDAARGOS_631 plasmid unnamed2, complete sequence	37259-37288	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP041929	Klebsiella pneumoniae strain 18-2374 plasmid pSECR18-2374B, complete sequence	43371-43400	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	CP044030	Klebsiella pneumoniae strain RJY9645 plasmid pY9645-105, complete sequence	4434-4463	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP019050	Klebsiella pneumoniae subsp. pneumoniae strain RJA166 plasmid pRJA166c, complete sequence	81399-81428	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP036373	Klebsiella pneumoniae strain WCHKP020037 plasmid p1_020037, complete sequence	34778-34807	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP021962	Klebsiella pneumoniae strain AR_0139 plasmid tig00000008, complete sequence	39905-39934	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP008931	Klebsiella pneumoniae strain PMK1 plasmid pPMK1-B, complete sequence	8136-8165	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP020063	Klebsiella pneumoniae strain AR_0117 plasmid unitig_2, complete sequence	34968-34997	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP015755	Klebsiella pneumoniae strain W14 plasmid unnamed2, complete sequence	27846-27875	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP016924	Klebsiella pneumoniae isolate 23 plasmid pIncFIB_DHQP1400954, complete sequence	98891-98920	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP032187	Klebsiella pneumoniae strain AR_0075 plasmid unnamed2, complete sequence	69810-69839	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	CP052264	Klebsiella pneumoniae strain E16KP0288 plasmid pE16K0288-2, complete sequence	37086-37115	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	CP053410	Salmonella enterica strain 2014K-0203 plasmid unnamed, complete sequence	59296-59325	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP016161	Klebsiella pneumoniae strain TH1 isolate TH1 plasmid unnamed2, complete sequence	40536-40565	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	CP050276	Klebsiella pneumoniae strain 10553 plasmid unnamed1, complete sequence	65219-65248	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP047636	Klebsiella pneumoniae strain K2606 plasmid unnamed3, complete sequence	86872-86901	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	CP058330	Klebsiella phage vB_Kpn_1825-KPC53 chromosome phage_vB_Kpn_1825-KPC53, complete sequence	90457-90486	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP028550	Klebsiella variicola strain WCHKP19 plasmid p2_020019, complete sequence	78745-78774	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP026134	Klebsiella pneumoniae strain F5 plasmid pF5_2, complete sequence	41018-41047	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP022128	Klebsiella pneumoniae strain DHQP1605752_NV plasmid p1605752FIB_2, complete sequence	107746-107775	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP025467	Klebsiella pneumoniae strain JS187 plasmid p187-1, complete sequence	97602-97631	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP012570	Klebsiella pneumoniae strain UCLAOXA232KP plasmid pUCLAOXA232-4.X, complete sequence	75807-75836	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP031791	Klebsiella pneumoniae strain KSB1_1I-sc-2280289 plasmid unnamed2, complete sequence	75308-75337	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP031803	Klebsiella pneumoniae strain MSB1_8A-sc-2280397 plasmid unnamed3, complete sequence	75809-75838	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP040026	Klebsiella pneumoniae strain KPC160132 plasmid pIncFI-L132, complete sequence	93799-93828	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP028997	Klebsiella pneumoniae strain AR_0079 plasmid unnamed4, complete sequence	55069-55098	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP040729	Klebsiella pneumoniae strain KpvST147B_SE1_1_NDM plasmid pKpvST147B_5, complete sequence	95185-95214	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP046951	Klebsiella pneumoniae strain BD_DM_914 plasmid punnamed2, complete sequence	114299-114328	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP046941	Klebsiella pneumoniae strain BD_DM_697 plasmid punnamed2	114272-114301	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP012565	Klebsiella pneumoniae strain UCLAOXA232KP plasmid pUCLAOXA232-4, complete sequence	75807-75836	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP046383	Klebsiella pneumoniae strain BD_DM_782 plasmid punnamed2, complete sequence	114280-114309	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP050365	Klebsiella pneumoniae strain 47733 plasmid p47733_IncFIB, complete sequence	24171-24200	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP030268	Klebsiella pneumoniae subsp. pneumoniae strain SC-7 plasmid pSC7-IncFIB-110K, complete sequence	29642-29671	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP026146	Klebsiella pneumoniae strain F132 plasmid pF132_1, complete sequence	51094-51123	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP026150	Klebsiella pneumoniae strain F138 plasmid pF138_1, complete sequence	34982-35011	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP045677	Klebsiella pneumoniae strain WSD411 plasmid pWSD411_4, complete sequence	90348-90377	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP026138	Klebsiella pneumoniae strain F77 plasmid pF77_2, complete sequence	10241-10270	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP026165	Klebsiella pneumoniae strain F81 plasmid pF81_1, complete sequence	108128-108157	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP027155	Klebsiella pneumoniae strain AR_0363 plasmid unnamed6	31865-31894	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP014756	Klebsiella pneumoniae strain AATZP plasmid pKPN-04f, complete sequence	85844-85873	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP021945	Klebsiella pneumoniae strain AR_0152 plasmid tig00000194, complete sequence	72796-72825	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	CP052390	Klebsiella pneumoniae strain C17KP0052 plasmid pC17KP0052-2, complete sequence	75992-76021	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_AP014953	Klebsiella oxytoca strain JKo3 plasmid pKO_JKo3_2, complete sequence	76564-76593	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NC_016838	Klebsiella pneumoniae subsp. pneumoniae HS11286 plasmid pKPHS1, complete sequence	86578-86607	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP028544	Klebsiella pneumoniae subsp. pneumoniae strain SCKP020143 plasmid p2_020143, complete sequence	71873-71902	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_CP044046	Klebsiella pneumoniae strain FDAARGOS_629 plasmid unnamed4, complete sequence	19780-19809	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	CP050287	Klebsiella pneumoniae strain 9630 plasmid unnamed2, complete sequence	75418-75447	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_KY354306	Klebsiella pneumoniae strain 301 plasmid pKP301b, complete sequence	15511-15540	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	NZ_MF144193	Klebsiella pneumoniae strain 205880 plasmid p205880-NR1, complete sequence	75750-75779	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	LR134218	Klebsiella aerogenes strain NCTC10317 genome assembly, plasmid: 2	107824-107853	8	0.733
NZ_CP048921_1	1.2\|115171\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115171-115200	30	MK422451	Klebsiella phage ST13-OXA48phi12.3, complete genome	34015-34044	8	0.733
NZ_CP048921_1	1.5\|115369\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115369-115398	30	MT416612	Bacillus phage YungSlug, complete genome	84580-84609	8	0.733
NZ_CP048921_1	1.5\|115369\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115369-115398	30	MT586120	Synechococcus phage S-CAM7 isolate 0809CC03, complete genome	16437-16466	8	0.733
NZ_CP048921_1	1.5\|115369\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115369-115398	30	MT586120	Synechococcus phage S-CAM7 isolate 0809CC03, complete genome	16674-16703	8	0.733
NZ_CP048921_1	1.5\|115369\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115369-115398	30	NC_031927	Synechococcus phage S-CAM7 isolate 0910CC49, complete genome	16923-16952	8	0.733
NZ_CP048921_1	1.5\|115369\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115369-115398	30	KU686213	Synechococcus phage S-CAM7 isolate 0910SB42, complete genome	17841-17870	8	0.733
NZ_CP048921_1	1.12\|115831\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115831-115860	30	NZ_CP038597	Salmonella enterica subsp. enterica serovar Hadar strain 12-2388 plasmid p12-2388.2, complete sequence	31442-31471	8	0.733
NZ_CP048921_1	1.12\|115831\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115831-115860	30	NC_011422	Salmonella enterica subsp. enterica serovar Typhi str. 404ty plasmid pBSSB1, complete sequence	13886-13915	8	0.733
NZ_CP048921_1	1.12\|115831\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115831-115860	30	NC_041884	Acinetobacter phage vB_AbaM_ME3, complete genome	18014-18043	8	0.733
NZ_CP048921_1	1.12\|115831\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115831-115860	30	NZ_AP018256	Calothrix sp. NIES-4071 plasmid plasmid1 DNA, complete genome	213180-213209	8	0.733
NZ_CP048921_1	1.1\|115105\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115105-115134	30	MG945474	UNVERIFIED: Microviridae sp. isolate 531-1602, complete genome	1380-1409	9	0.7
NZ_CP048921_1	1.7\|115501\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115501-115530	30	NZ_AP021877	Desulfosarcina ovata strain 28bB2T plasmid Do28_1, complete sequence	4743-4772	9	0.7
NZ_CP048921_1	1.11\|115765\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115765-115794	30	MH370378	Salmonella phage S131, complete genome	61171-61200	9	0.7
NZ_CP048921_1	1.11\|115765\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115765-115794	30	MH370377	Salmonella phage S130, partial genome	61171-61200	9	0.7
NZ_CP048921_1	1.11\|115765\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115765-115794	30	MN316588	Escherichia virus VEc33, complete genome	46133-46162	9	0.7
NZ_CP048921_1	1.12\|115831\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115831-115860	30	MN693392	Marine virus AFVG_25M95, complete genome	15484-15513	9	0.7
NZ_CP048921_1	1.12\|115831\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115831-115860	30	MN693222	Marine virus AFVG_25M67, complete genome	27710-27739	10	0.667

1. spacer 1.14|115963|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to MG788324 (Lactobacillus phage PM411, complete genome) position: , mismatch: 0, identity: 1.0

agtggtgtactcatagtcttttccctccat	CRISPR spacer
agtggtgtactcatagtcttttccctccat	Protospacer
******************************

2. spacer 1.14|115963|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024415 (Lactobacillus plantarum strain ATCC 8014 plasmid pLP39, complete sequence) position: , mismatch: 1, identity: 0.967

agtggtgtactcatagtcttttccctccat	CRISPR spacer
agtggtgtactcatagttttttccctccat	Protospacer
*****************.************

3. spacer 1.14|115963|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018210 (Lactobacillus plantarum strain BLS41 plasmid pLPBLS41_1, complete sequence) position: , mismatch: 1, identity: 0.967

agtggtgtactcatagtcttttccctccat	CRISPR spacer
agtggtgtactcatagttttttccctccat	Protospacer
*****************.************

4. spacer 1.4|115303|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NC_004305 (Lactobacillus phage phig1e, complete genome) position: , mismatch: 3, identity: 0.9

ctcaactcgaggtcgcgtagattgtccagt	CRISPR spacer
ctcaattcgaggtcgcgtagattgtcaagc	Protospacer
*****.******************** **.

5. spacer 1.4|115303|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to X98106 (Lactobacillus bacteriophage phig1e complete genomic DNA) position: , mismatch: 3, identity: 0.9

ctcaactcgaggtcgcgtagattgtccagt	CRISPR spacer
ctcaattcgaggtcgcgtagattgtcaagc	Protospacer
*****.******************** **.

6. spacer 1.10|115699|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NC_047764 (Lactobacillus phage P1, complete genome) position: , mismatch: 3, identity: 0.9

aaattattgttaaaattaggttattcaatt	CRISPR spacer
gcactattgttaaaattaggttattcaatt	Protospacer
. *.**************************

7. spacer 1.10|115699|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to KY381600 (Lactobacillus phage P2, complete genome) position: , mismatch: 3, identity: 0.9

aaattattgttaaaattaggttattcaatt	CRISPR spacer
gcactattgttaaaattaggttattcaatt	Protospacer
. *.**************************

8. spacer 1.10|115699|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to MT074146 (Bacteroides phage SJC03, complete genome) position: , mismatch: 4, identity: 0.867

aaattattgttaaaattaggttattcaatt--	CRISPR spacer
aaattattgttaaaattagttaat--aattat	Protospacer
******************* * **  ****

9. spacer 1.10|115699|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to JX486088 (Lactobacillus phage ATCC 8014-B2, complete genome) position: , mismatch: 4, identity: 0.867

aaattattg-ttaaaattaggttattcaatt	CRISPR spacer
-aattagggtttataattaggttattcaatt	Protospacer
 *****  * *** *****************

10. spacer 1.9|115633|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012653 (Lactobacillus plantarum strain HFC8 isolate Lactobacillus plantarum plasmid pMK07, complete sequence) position: , mismatch: 5, identity: 0.833

ctagtacctgttgaatcaaaacgatcagca	CRISPR spacer
caaagacttgttgaatcaaaacgattagca	Protospacer
* *. **.*****************.****

11. spacer 1.10|115699|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NC_047926 (Lactobacillus phage Semele, complete genome) position: , mismatch: 5, identity: 0.833

--aaattattgttaaaattaggttattcaatt	CRISPR spacer
cctaat--tcgttataattaggttattcaatt	Protospacer
   ***  *.**** *****************

12. spacer 1.12|115831|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to MK448975 (Streptococcus phage Javan526, complete genome) position: , mismatch: 5, identity: 0.833

ttggaacaaagaaagaagttaaagcattac	CRISPR spacer
ggggaacaaagaaagaagtaaaagctttgc	Protospacer
  ***************** ***** **.*

13. spacer 1.12|115831|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to MK448782 (Streptococcus phage Javan501, complete genome) position: , mismatch: 5, identity: 0.833

ttggaacaaagaaagaagttaaagcattac	CRISPR spacer
ggggaacaaagaaagaagtaaaagctttgc	Protospacer
  ***************** ***** **.*

14. spacer 1.12|115831|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NC_022111 (Prevotella sp. oral taxon 299 str. F0039 plasmid, complete sequence) position: , mismatch: 5, identity: 0.833

ttggaacaaagaaagaagttaaagcattac	CRISPR spacer
ttggaacaaagaaagaactaaaagaacaac	Protospacer
***************** * **** *. **

15. spacer 1.10|115699|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NC_015427 (Clostridium botulinum BKT015925 plasmid p4BKT015925, complete sequence) position: , mismatch: 6, identity: 0.8

aaattattgttaaaattaggttattcaatt	CRISPR spacer
gatttattgttaaaaataggttatacagat	Protospacer
.* ************ ******** **. *

16. spacer 1.12|115831|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to MT074138 (Bacteroides phage DAC17, complete genome) position: , mismatch: 6, identity: 0.8

ttggaacaaagaaagaagttaaagcattac	CRISPR spacer
gaggaacaaaggaagaagttaaatcaaaac	Protospacer
  *********.*********** **  **

17. spacer 1.12|115831|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to MT074136 (Bacteroides phage DAC15, complete genome) position: , mismatch: 6, identity: 0.8

ttggaacaaagaaagaagttaaagcattac	CRISPR spacer
gaggaacaaaggaagaagttaaatcaaaac	Protospacer
  *********.*********** **  **

18. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NC_020841 (Psychrobacter phage pOW20-A genomic sequence) position: , mismatch: 7, identity: 0.767

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
aagccctaagcaaccatgctgacgaatatc	Protospacer
.*..*  ******  ***************

19. spacer 1.8|115567|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NC_014628 (Paenibacillus polymyxa SC2 plasmid pSC2, complete sequence) position: , mismatch: 7, identity: 0.767

agacatggcaaagtgacgactagaaccatt	CRISPR spacer
gtacatggcaaagtggcgacaagaacgtta	Protospacer
. *************.**** *****  *

20. spacer 1.9|115633|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to MF001355 (Proteus phage PM2, partial genome) position: , mismatch: 7, identity: 0.767

ctagtacctgttgaatcaaaacgatcagca	CRISPR spacer
tcaatacctgtgcaatcaaaacgatcaaaa	Protospacer
..*.*******  **************. *

21. spacer 1.10|115699|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to MK448925 (Streptococcus phage Javan386, complete genome) position: , mismatch: 7, identity: 0.767

aaattattgttaaaattaggttattcaatt	CRISPR spacer
aagaagttgttaaaatcaggttattaaatc	Protospacer
**.  .**********.******** ***.

22. spacer 1.10|115699|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to MG557979 (Lactobacillus phage Lpa804, complete genome) position: , mismatch: 7, identity: 0.767

aaatta--ttgttaaaattaggttattcaatt	CRISPR spacer
--cctagtttgctataattaggttattcaatc	Protospacer
   .**  ***.** ****************.

23. spacer 1.12|115831|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to CP024687 (Bacillus wiedmannii bv. thuringiensis strain FCC41 plasmid pFCC41-3-257K, complete sequence) position: , mismatch: 7, identity: 0.767

----ttggaacaaagaaagaagttaaagcattac	CRISPR spacer
cacttt----taaagaaagaagtgaaagcattaa	Protospacer
    **    .************ *********

24. spacer 1.12|115831|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015180 (Bacillus thuringiensis serovar alesti strain BGSC 4C1 plasmid pBMB71, complete sequence) position: , mismatch: 7, identity: 0.767

----ttggaacaaagaaagaagttaaagcattac	CRISPR spacer
cacttt----taaagaaagaagtgaaagcattaa	Protospacer
    **    .************ *********

25. spacer 1.12|115831|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NC_020240 (Bacillus thuringiensis serovar kurstaki str. HD73 plasmid pAW63, complete sequence) position: , mismatch: 7, identity: 0.767

----ttggaacaaagaaagaagttaaagcattac	CRISPR spacer
cacttt----taaagaaagaagtgaaagcattaa	Protospacer
    **    .************ *********

26. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021940 (Klebsiella pneumoniae strain AR_0145 plasmid tig00000209, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

27. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012427 (Klebsiella pneumoniae strain KP5 plasmid pSg1-1, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

28. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP044034 (Klebsiella pneumoniae strain FDAARGOS_631 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

29. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP041929 (Klebsiella pneumoniae strain 18-2374 plasmid pSECR18-2374B, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

30. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to CP044030 (Klebsiella pneumoniae strain RJY9645 plasmid pY9645-105, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

31. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019050 (Klebsiella pneumoniae subsp. pneumoniae strain RJA166 plasmid pRJA166c, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

32. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP036373 (Klebsiella pneumoniae strain WCHKP020037 plasmid p1_020037, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

33. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021962 (Klebsiella pneumoniae strain AR_0139 plasmid tig00000008, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

34. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP008931 (Klebsiella pneumoniae strain PMK1 plasmid pPMK1-B, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

35. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020063 (Klebsiella pneumoniae strain AR_0117 plasmid unitig_2, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

36. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015755 (Klebsiella pneumoniae strain W14 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

37. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016924 (Klebsiella pneumoniae isolate 23 plasmid pIncFIB_DHQP1400954, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

38. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032187 (Klebsiella pneumoniae strain AR_0075 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

39. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to CP052264 (Klebsiella pneumoniae strain E16KP0288 plasmid pE16K0288-2, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

40. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to CP053410 (Salmonella enterica strain 2014K-0203 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

41. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016161 (Klebsiella pneumoniae strain TH1 isolate TH1 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

42. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to CP050276 (Klebsiella pneumoniae strain 10553 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

43. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP047636 (Klebsiella pneumoniae strain K2606 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

44. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to CP058330 (Klebsiella phage vB_Kpn_1825-KPC53 chromosome phage_vB_Kpn_1825-KPC53, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

45. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP028550 (Klebsiella variicola strain WCHKP19 plasmid p2_020019, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

46. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026134 (Klebsiella pneumoniae strain F5 plasmid pF5_2, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

47. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022128 (Klebsiella pneumoniae strain DHQP1605752_NV plasmid p1605752FIB_2, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

48. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025467 (Klebsiella pneumoniae strain JS187 plasmid p187-1, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

49. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012570 (Klebsiella pneumoniae strain UCLAOXA232KP plasmid pUCLAOXA232-4.X, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

50. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP031791 (Klebsiella pneumoniae strain KSB1_1I-sc-2280289 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

51. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP031803 (Klebsiella pneumoniae strain MSB1_8A-sc-2280397 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

52. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040026 (Klebsiella pneumoniae strain KPC160132 plasmid pIncFI-L132, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

53. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP028997 (Klebsiella pneumoniae strain AR_0079 plasmid unnamed4, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

54. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040729 (Klebsiella pneumoniae strain KpvST147B_SE1_1_NDM plasmid pKpvST147B_5, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

55. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046951 (Klebsiella pneumoniae strain BD_DM_914 plasmid punnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

56. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046941 (Klebsiella pneumoniae strain BD_DM_697 plasmid punnamed2) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

57. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012565 (Klebsiella pneumoniae strain UCLAOXA232KP plasmid pUCLAOXA232-4, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

58. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046383 (Klebsiella pneumoniae strain BD_DM_782 plasmid punnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

59. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP050365 (Klebsiella pneumoniae strain 47733 plasmid p47733_IncFIB, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

60. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030268 (Klebsiella pneumoniae subsp. pneumoniae strain SC-7 plasmid pSC7-IncFIB-110K, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

61. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026146 (Klebsiella pneumoniae strain F132 plasmid pF132_1, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

62. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026150 (Klebsiella pneumoniae strain F138 plasmid pF138_1, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

63. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045677 (Klebsiella pneumoniae strain WSD411 plasmid pWSD411_4, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

64. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026138 (Klebsiella pneumoniae strain F77 plasmid pF77_2, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

65. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026165 (Klebsiella pneumoniae strain F81 plasmid pF81_1, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

66. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP027155 (Klebsiella pneumoniae strain AR_0363 plasmid unnamed6) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

67. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014756 (Klebsiella pneumoniae strain AATZP plasmid pKPN-04f, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

68. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021945 (Klebsiella pneumoniae strain AR_0152 plasmid tig00000194, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

69. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to CP052390 (Klebsiella pneumoniae strain C17KP0052 plasmid pC17KP0052-2, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

70. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP014953 (Klebsiella oxytoca strain JKo3 plasmid pKO_JKo3_2, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

71. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NC_016838 (Klebsiella pneumoniae subsp. pneumoniae HS11286 plasmid pKPHS1, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

72. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP028544 (Klebsiella pneumoniae subsp. pneumoniae strain SCKP020143 plasmid p2_020143, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

73. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP044046 (Klebsiella pneumoniae strain FDAARGOS_629 plasmid unnamed4, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

74. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to CP050287 (Klebsiella pneumoniae strain 9630 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

75. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KY354306 (Klebsiella pneumoniae strain 301 plasmid pKP301b, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

76. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MF144193 (Klebsiella pneumoniae strain 205880 plasmid p205880-NR1, complete sequence) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

77. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to LR134218 (Klebsiella aerogenes strain NCTC10317 genome assembly, plasmid: 2) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

78. spacer 1.2|115171|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to MK422451 (Klebsiella phage ST13-OXA48phi12.3, complete genome) position: , mismatch: 8, identity: 0.733

gaatcgaaagcaagaatgctgacgaatatc	CRISPR spacer
acatcgaaagcaaacatgctgacgatagac	Protospacer
. ***********. **********  . *

79. spacer 1.5|115369|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to MT416612 (Bacillus phage YungSlug, complete genome) position: , mismatch: 8, identity: 0.733

cagtagctccaacaggaacagtaaaattgt	CRISPR spacer
agttcgctccaacaggaacagtagagtttg	Protospacer
 . * ******************.*.**

80. spacer 1.5|115369|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to MT586120 (Synechococcus phage S-CAM7 isolate 0809CC03, complete genome) position: , mismatch: 8, identity: 0.733

cagtagctccaacaggaacagtaaaattgt	CRISPR spacer
cagtagcaccaacaggaccagtagcaccag	Protospacer
******* ********* *****. *...

81. spacer 1.5|115369|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to MT586120 (Synechococcus phage S-CAM7 isolate 0809CC03, complete genome) position: , mismatch: 8, identity: 0.733

cagtagctccaacaggaacagtaaaattgt	CRISPR spacer
cagtagcaccaacaggaccagtagcaccag	Protospacer
******* ********* *****. *...

82. spacer 1.5|115369|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NC_031927 (Synechococcus phage S-CAM7 isolate 0910CC49, complete genome) position: , mismatch: 8, identity: 0.733

cagtagctccaacaggaacagtaaaattgt	CRISPR spacer
cagtagcaccaacaggaccagtagcaccag	Protospacer
******* ********* *****. *...

83. spacer 1.5|115369|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to KU686213 (Synechococcus phage S-CAM7 isolate 0910SB42, complete genome) position: , mismatch: 8, identity: 0.733

cagtagctccaacaggaacagtaaaattgt	CRISPR spacer
cagtagcaccaacaggaccagtagcaccag	Protospacer
******* ********* *****. *...

84. spacer 1.12|115831|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038597 (Salmonella enterica subsp. enterica serovar Hadar strain 12-2388 plasmid p12-2388.2, complete sequence) position: , mismatch: 8, identity: 0.733

ttggaacaaagaaagaagttaaagcattac	CRISPR spacer
aaaaatcagagaaagaaattaaagcattaa	Protospacer
  ..* **.********.***********

85. spacer 1.12|115831|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NC_011422 (Salmonella enterica subsp. enterica serovar Typhi str. 404ty plasmid pBSSB1, complete sequence) position: , mismatch: 8, identity: 0.733

ttggaacaaagaaagaagttaaagcattac	CRISPR spacer
aaaaatcagagaaagaaattaaagcattaa	Protospacer
  ..* **.********.***********

86. spacer 1.12|115831|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NC_041884 (Acinetobacter phage vB_AbaM_ME3, complete genome) position: , mismatch: 8, identity: 0.733

ttggaacaaagaaagaagttaaagcattac	CRISPR spacer
ctgcaacaaaggaagaagttaaagacgaat	Protospacer
.** *******.************    *.

87. spacer 1.12|115831|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP018256 (Calothrix sp. NIES-4071 plasmid plasmid1 DNA, complete genome) position: , mismatch: 8, identity: 0.733

ttggaacaaagaaagaagttaaagcattac	CRISPR spacer
aaagaacaagcaaagaagttaaagcaagcc	Protospacer
  .******. ***************   *

88. spacer 1.1|115105|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to MG945474 (UNVERIFIED: Microviridae sp. isolate 531-1602, complete genome) position: , mismatch: 9, identity: 0.7

gacgatcgggctgataacctaatctggtca	CRISPR spacer
tggcatcgggcttataacctgatctggaat	Protospacer
 .  ******** *******.******

89. spacer 1.7|115501|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP021877 (Desulfosarcina ovata strain 28bB2T plasmid Do28_1, complete sequence) position: , mismatch: 9, identity: 0.7

ccgatcacccactagcaatagggccagaac	CRISPR spacer
gggatcacccactaaaaatagggcccccgg	Protospacer
  ************. *********   .

90. spacer 1.11|115765|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to MH370378 (Salmonella phage S131, complete genome) position: , mismatch: 9, identity: 0.7

ccttactaattaatccggctccgatggaac	CRISPR spacer
aagcactaaataatccggctccgattcgtc	Protospacer
   .***** ***************  . *

91. spacer 1.11|115765|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to MH370377 (Salmonella phage S130, partial genome) position: , mismatch: 9, identity: 0.7

ccttactaattaatccggctccgatggaac	CRISPR spacer
aagcactaaataatccggctccgattcgtc	Protospacer
   .***** ***************  . *

92. spacer 1.11|115765|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to MN316588 (Escherichia virus VEc33, complete genome) position: , mismatch: 9, identity: 0.7

ccttactaattaatccggctccgatggaac	CRISPR spacer
aagcactaaataatccggctccgattcgtc	Protospacer
   .***** ***************  . *

93. spacer 1.12|115831|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to MN693392 (Marine virus AFVG_25M95, complete genome) position: , mismatch: 9, identity: 0.7

ttggaacaaagaaagaagttaaagcattac	CRISPR spacer
gaatagtaaagaaagatgttaaagcatttg	Protospacer
  . *..********* ***********

94. spacer 1.12|115831|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to MN693222 (Marine virus AFVG_25M67, complete genome) position: , mismatch: 10, identity: 0.667

ttggaacaaagaaagaagttaaagcattac	CRISPR spacer
gctgaacaaagaaagaagttacagataggt	Protospacer
 . ****************** **    ..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

322238 : 369311

Bacillus_virus(50.0%)

bacteriocin,protease

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_163626850.1\|322238_322802_-\|protease	matrixin family metalloprotease	NA	NA	NA	NA
WP_016511451.1\|322995_323664_+	ribose 5-phosphate isomerase A	NA	NA	NA	NA
WP_063722889.1\|323821_325327_+	multicopper oxidase domain-containing protein	NA	NA	NA	NA
WP_163626852.1\|325591_325960_+	DUF1304 domain-containing protein	NA	NA	NA	NA
WP_003641932.1\|326072_326582_-	YbhB/YbcL family Raf kinase inhibitor-like protein	NA	NA	NA	NA
WP_011100975.1\|326612_327809_-	DUF2075 domain-containing protein	NA	NA	NA	NA
WP_003641934.1\|327918_328389_+	Rrf2 family transcriptional regulator	NA	NA	NA	NA
WP_003641935.1\|328407_328863_+	hypothetical protein	NA	NA	NA	NA
WP_003641936.1\|328966_329539_+	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit	NA	NA	NA	NA
WP_003646441.1\|329704_330625_-	ribonucleoside hydrolase RihC	NA	NA	NA	NA
WP_015825107.1\|330761_331661_+	oxidoreductase	NA	NA	NA	NA
WP_015825108.1\|332100_333981_+	hypothetical protein	NA	NA	NA	NA
WP_003646442.1\|334152_334599_-	ribonuclease H	NA	NA	NA	NA
WP_003641940.1\|334836_336363_+	ABC transporter permease/substrate-binding protein	NA	NA	NA	NA
WP_163626854.1\|336363_337335_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	4.6e-24	32.2
WP_015825110.1\|337412_338744_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_163626856.1\|339209_340727_+	glycerol kinase GlpK	NA	NA	NA	NA
WP_163626858.1\|340741_342571_+	type 1 glycerol-3-phosphate oxidase	NA	NA	NA	NA
WP_161048331.1\|342588_343308_+	MIP family channel protein	NA	NA	NA	NA
WP_163626860.1\|343502_345851_+	MucBP domain-containing protein	NA	NA	NA	NA
WP_011100983.1\|347536_347956_+	hypothetical protein	NA	NA	NA	NA
WP_011100984.1\|348004_348268_+	hypothetical protein	NA	NA	NA	NA
WP_003641960.1\|348379_348655_+	hypothetical protein	NA	NA	NA	NA
WP_015379760.1\|349036_349654_-	sugar O-acetyltransferase	NA	NA	NA	NA
WP_016511579.1\|349657_350812_-	MFS transporter	NA	NA	NA	NA
WP_015825116.1\|350815_351607_-	HAD family hydrolase	NA	NA	NA	NA
WP_015379762.1\|351677_352550_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_163626862.1\|352709_353525_+	HAD family phosphatase	NA	NA	NA	NA
WP_003643798.1\|354052_355429_+	branched-chain amino acid transport system II carrier protein	NA	NA	NA	NA
WP_011100995.1\|355473_356658_+	cation:proton antiporter	NA	NA	NA	NA
WP_046947804.1\|358158_358827_-	hypothetical protein	NA	NA	NA	NA
WP_153302738.1\|359419_359587_+	hypothetical protein	NA	NA	NA	NA
WP_163626864.1\|359604_360945_+	GHKL domain-containing protein	NA	NA	NA	NA
WP_070083240.1\|360945_361689_+	response regulator transcription factor	NA	NA	NA	NA
WP_015825123.1\|361994_362768_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_003643811.1\|362866_363025_-\|bacteriocin	two-peptide bacteriocin plantaricin EF subunit PlnF	NA	NA	NA	NA
WP_003641985.1\|363049_363220_-\|bacteriocin	two-peptide bacteriocin plantaricin EF subunit PlnE	NA	NA	NA	NA
WP_015825125.1\|363486_365637_+	peptide cleavage/export ABC transporter	W8CYL7	Bacillus_phage	6.1e-45	27.9
WP_015825126.1\|365652_367029_+	HlyD family secretion protein	NA	NA	NA	NA
WP_015825127.1\|367118_367808_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_015825129.1\|368630_369311_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_2

1185682 : 1193043

Lactobacillus_phage(83.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003643099.1\|1185682_1186630_-	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	2.7e-178	100.0
WP_003643097.1\|1186973_1187588_+	NAD(P)H-dependent oxidoreductase	A0A2P0ZL77	Lactobacillus_phage	6.3e-112	100.0
WP_022638021.1\|1187590_1190029_+	flavocytochrome c	A0A2P0ZL82	Lactobacillus_phage	0.0e+00	99.6
WP_003643095.1\|1190116_1190677_+	hypothetical protein	A0A2P0ZL75	Lactobacillus_phage	2.7e-101	100.0
WP_011101401.1\|1190747_1191188_-	nucleoside 2-deoxyribosyltransferase	A0A2P0ZL88	Lactobacillus_phage	3.0e-76	98.6
WP_015380221.1\|1191283_1191421_+	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_070083336.1\|1192047_1193043_+	glycosyltransferase family 2 protein	S5FKN0	Shigella_phage	2.0e-51	38.2

DBSCAN-SWA_3

1304314 : 1393626

103

Lactobacillus_phage(71.43%)

capsid,protease,holin,head,tRNA,portal,terminase,integrase,tail

attL 1295080:1295095|attR 1344512:1344527

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1295080:1295095	attL	NA	NA	NA	NA
WP_015825501.1\|1304314_1305361_+\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2H4UW22	Bodo_saltans_virus	4.0e-26	37.9
WP_003644300.1\|1305369_1307787_+\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_163627133.1\|1307933_1309139_+	endolytic transglycosylase MltG	NA	NA	NA	NA
WP_003640313.1\|1309157_1309787_+	uridine kinase	A0A1V0SAA3	Catovirus	1.7e-35	39.6
WP_003640314.1\|1309897_1310380_+	transcription elongation factor GreA	NA	NA	NA	NA
WP_015825502.1\|1311443_1312166_-	hypothetical protein	NA	NA	NA	NA
WP_003640318.1\|1312166_1312622_-	LytTR family transcriptional regulator	NA	NA	NA	NA
WP_003644301.1\|1312806_1313109_+	hypothetical protein	NA	NA	NA	NA
WP_045351247.1\|1313225_1315871_-	YfhO family protein	NA	NA	NA	NA
WP_003640321.1\|1316070_1318107_+	penicillin-binding protein 2	NA	NA	NA	NA
WP_003638573.1\|1318232_1318382_+	50S ribosomal protein L33	NA	NA	NA	NA
WP_003645173.1\|1318529_1319096_+	5-formyltetrahydrofolate cyclo-ligase	NA	NA	NA	NA
WP_003645172.1\|1319082_1319766_+\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
WP_003644303.1\|1319784_1320006_+	YqgQ family protein	NA	NA	NA	NA
WP_003644304.1\|1320023_1320986_+	ROK family glucokinase	NA	NA	NA	NA
WP_045351249.1\|1321257_1321893_+	type 1 glutamine amidotransferase-like domain-containing protein	NA	NA	NA	NA
WP_003644306.1\|1322120_1322534_+	rhodanese-like domain-containing protein	NA	NA	NA	NA
WP_003640329.1\|1322583_1322760_-	DUF3042 family protein	NA	NA	NA	NA
WP_003640330.1\|1322859_1323594_+	glycerophosphodiester phosphodiesterase	A0A0S2MYI4	Enterococcus_phage	4.5e-16	44.3
WP_003640331.1\|1323598_1324534_+\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_003644308.1\|1324645_1325026_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_003640333.1\|1325069_1326416_+	type I glutamate--ammonia ligase	NA	NA	NA	NA
WP_003640334.1\|1326550_1327486_+	hypothetical protein	NA	NA	NA	NA
WP_053338867.1\|1327475_1328432_+	hypothetical protein	NA	NA	NA	NA
WP_163627134.1\|1328448_1328988_+	2-deoxyuridine 5-triphosphate nucleotidohydrolase	NA	NA	NA	NA
WP_003645167.1\|1329034_1329373_-	hypothetical protein	NA	NA	NA	NA
WP_003640338.1\|1329430_1329631_-	hypothetical protein	NA	NA	NA	NA
WP_163627136.1\|1330178_1331318_-\|integrase	site-specific integrase	E9LUS1	Lactobacillus_phage	3.0e-115	56.2
WP_163627138.1\|1331491_1332067_+	hypothetical protein	NA	NA	NA	NA
WP_003641356.1\|1332263_1332578_-	hypothetical protein	NA	NA	NA	NA
WP_027822546.1\|1332762_1332945_-	hypothetical protein	A0A2P0ZL93	Lactobacillus_phage	8.8e-14	66.7
WP_163627140.1\|1333293_1333512_-	hypothetical protein	NA	NA	NA	NA
WP_163627142.1\|1333514_1334249_-	ion transporter	A0A1B0Y2S3	Lactobacillus_phage	1.2e-40	54.4
WP_163627144.1\|1334256_1334832_-	hypothetical protein	NA	NA	NA	NA
WP_099739138.1\|1334957_1335629_-	LexA family transcriptional regulator	D7RWL5	Brochothrix_phage	2.5e-45	45.1
WP_027821294.1\|1335821_1336037_+	helix-turn-helix transcriptional regulator	A0A2H4JBV7	uncultured_Caudovirales_phage	5.9e-17	71.0
WP_163627146.1\|1336043_1336787_+	hypothetical protein	A0A1P8BM06	Lactococcus_phage	4.4e-51	44.9
WP_050339257.1\|1336798_1337008_+	hypothetical protein	NA	NA	NA	NA
WP_163627148.1\|1337021_1337210_+	hypothetical protein	NA	NA	NA	NA
WP_163627150.1\|1337206_1337731_-	hypothetical protein	NA	NA	NA	NA
WP_163627152.1\|1337824_1338154_+	DUF771 domain-containing protein	E9LUT3	Lactobacillus_phage	8.1e-50	82.6
WP_033608473.1\|1338242_1338482_+	hypothetical protein	E9LUT6	Lactobacillus_phage	4.5e-34	83.5
WP_163627154.1\|1338493_1338658_+	hypothetical protein	E9LUT8	Lactobacillus_phage	2.1e-14	76.9
WP_163627156.1\|1338660_1338807_+	hypothetical protein	E9LUT9	Lactobacillus_phage	2.1e-18	97.9
WP_033614714.1\|1338806_1339340_+	hypothetical protein	E9LUU0	Lactobacillus_phage	1.1e-91	98.3
WP_016058363.1\|1339348_1340011_+	AAA family ATPase	E9LUU1	Lactobacillus_phage	4.2e-122	100.0
WP_163627158.1\|1340012_1340672_+	DUF669 domain-containing protein	E9LUU2	Lactobacillus_phage	2.7e-92	95.4
WP_163627160.1\|1340718_1341411_+	hypothetical protein	E9LUU3	Lactobacillus_phage	1.0e-131	98.7
WP_163627162.1\|1342224_1343010_+	ATP-binding protein	E9LUN6	Lactobacillus_phage	1.2e-131	90.4
WP_163627164.1\|1343239_1343740_+	hypothetical protein	O03915	Lactobacillus_phage	7.2e-58	67.3
WP_163627166.1\|1343736_1344117_+	hypothetical protein	NA	NA	NA	NA
WP_163627168.1\|1344170_1344329_+	hypothetical protein	E9LUP4	Lactobacillus_phage	1.3e-13	87.0
WP_022638818.1\|1344309_1344735_+	phage transcriptional activator RinA	E9LUP5	Lactobacillus_phage	3.1e-62	81.6
1344512:1344527	attR	NA	NA	NA	NA
WP_163627170.1\|1344998_1345937_+	hypothetical protein	NA	NA	NA	NA
WP_163627172.1\|1346108_1346768_+	HNH endonuclease	B8R694	Lactobacillus_phage	3.8e-22	37.6
WP_163627173.1\|1346959_1347394_+\|terminase	phage terminase small subunit P27 family	B8R648	Lactobacillus_phage	4.1e-17	38.5
WP_163627175.1\|1347380_1349297_+\|terminase	terminase large subunit	A0A0M7RDK9	Lactobacillus_phage	1.5e-135	42.0
WP_163627177.1\|1349518_1350637_+\|portal	phage portal protein	Q9AZM4	Lactococcus_phage	5.0e-67	41.2
WP_163627179.1\|1350608_1351214_+\|head,protease	HK97 family phage prohead protease	B8R651	Lactobacillus_phage	1.1e-39	49.1
WP_163627182.1\|1351220_1352603_+\|capsid	phage major capsid protein	A0A0M7RF71	Lactobacillus_phage	2.9e-96	61.6
WP_163627699.1\|1352679_1352970_+	hypothetical protein	A0A2P0ZLF2	Lactobacillus_phage	8.5e-35	77.9
WP_163627184.1\|1352970_1353318_+\|head	phage head closure protein	A0A2P0ZLF0	Lactobacillus_phage	8.0e-56	93.9
WP_163627186.1\|1353320_1353728_+	HK97 gp10 family phage protein	A0A2P0ZLE6	Lactobacillus_phage	2.7e-63	89.4
WP_163627188.1\|1353727_1354108_+	DUF806 family protein	A0A2P0ZLF4	Lactobacillus_phage	3.2e-58	88.9
WP_163627190.1\|1354123_1354777_+\|tail	phage tail protein	A0A2P0ZLH1	Lactobacillus_phage	3.1e-109	91.7
WP_097558080.1\|1354851_1355226_+	hypothetical protein	A0A2P0ZLH4	Lactobacillus_phage	3.5e-57	94.4
WP_097558081.1\|1355264_1355456_+	hypothetical protein	NA	NA	NA	NA
WP_163627192.1\|1355487_1360377_+	transglycosylase SLT domain-containing protein	A0A2P0ZLG0	Lactobacillus_phage	0.0e+00	55.9
WP_163627194.1\|1360436_1362209_+\|tail	phage tail protein	A0A2P0ZLH2	Lactobacillus_phage	6.1e-309	93.2
WP_163627195.1\|1362273_1364688_+	hypothetical protein	A0A2P0ZLF8	Lactobacillus_phage	0.0e+00	91.8
WP_163627197.1\|1364704_1367221_+\|tail	phage tail protein	K4I0E3	Lactobacillus_phage	1.1e-18	68.9
WP_163627199.1\|1367213_1367456_+	hypothetical protein	A0A2K9VDF6	Lactobacillus_phage	1.2e-31	93.8
WP_163627201.1\|1367459_1367621_+	hypothetical protein	A0A2P0ZLG1	Lactobacillus_phage	2.8e-19	94.3
WP_163627203.1\|1368263_1368770_+	hypothetical protein	Q597U5	Lactobacillus_virus	1.1e-48	66.4
WP_163627205.1\|1368781_1369954_+	LysM peptidoglycan-binding domain-containing protein	E9LUR8	Lactobacillus_phage	1.4e-200	89.2
WP_054519162.1\|1369953_1370217_+\|holin	holin	E9LUR9	Lactobacillus_phage	1.0e-34	89.7
WP_163627207.1\|1370226_1370601_+\|holin	holin	A0A2K9VCG4	Lactobacillus_phage	1.3e-14	66.2
WP_003640341.1\|1371717_1371873_-	hypothetical protein	NA	NA	NA	NA
WP_003645165.1\|1372276_1372906_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_003640343.1\|1373063_1373372_+	50S ribosomal protein L21	NA	NA	NA	NA
WP_003640344.1\|1373393_1373729_+\|protease	ribosomal-processing cysteine protease Prp	NA	NA	NA	NA
WP_003638594.1\|1373753_1374032_+	50S ribosomal protein L27	NA	NA	NA	NA
WP_003645164.1\|1374225_1375287_+	aminopeptidase P family protein	NA	NA	NA	NA
WP_003640346.1\|1375357_1375915_+	elongation factor P	NA	NA	NA	NA
WP_003640347.1\|1375964_1376423_+	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_013355496.1\|1376419_1376839_+	transcription antitermination factor NusB	NA	NA	NA	NA
WP_003645162.1\|1376985_1377846_+	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	A0A249XZQ2	Enterococcus_phage	1.1e-32	40.1
WP_003645161.1\|1377838_1379182_+	exodeoxyribonuclease VII large subunit	A0A160DEV2	Gordonia_phage	6.7e-26	30.8
WP_003640351.1\|1379181_1379412_+	exodeoxyribonuclease VII small subunit	NA	NA	NA	NA
WP_163627209.1\|1379404_1380295_+	polyprenyl synthetase family protein	NA	NA	NA	NA
WP_003640353.1\|1380309_1381128_+	TlyA family rRNA (cytidine-2'-O)-methyltransferase	NA	NA	NA	NA
WP_003640354.1\|1381211_1381670_+	arginine repressor	NA	NA	NA	NA
WP_003645158.1\|1381772_1383467_+	DNA repair protein RecN	NA	NA	NA	NA
WP_003644315.1\|1383832_1385029_+\|holin	betaine/proline/choline family ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	3.0e-17	46.2
WP_003644316.1\|1385025_1385655_+	ABC transporter permease	NA	NA	NA	NA
WP_003640358.1\|1385667_1386603_+	osmoprotectant ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_003640359.1\|1386602_1387256_+	ABC transporter permease	NA	NA	NA	NA
WP_003644317.1\|1387461_1387815_-	hypothetical protein	NA	NA	NA	NA
WP_003640361.1\|1387989_1388610_+	guanylate kinase	A0A0M5KCK5	Mollivirus	1.4e-10	33.6
WP_003640362.1\|1388606_1388819_+	DNA-directed RNA polymerase subunit omega	NA	NA	NA	NA
WP_003644318.1\|1388982_1390209_+	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	Q9HH70	Methanothermobacter_phage	7.5e-40	33.1
WP_070083382.1\|1390231_1392649_+	primosomal protein N'	NA	NA	NA	NA
WP_003645154.1\|1392672_1393626_+\|tRNA	methionyl-tRNA formyltransferase	E3SNR5	Prochlorococcus_phage	1.7e-10	31.4

DBSCAN-SWA_4

1755663 : 1801145

Lactobacillus_phage(18.18%)

integrase,tRNA,transposase,protease

attL 1781123:1781140|attR 1807971:1807988

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003640716.1\|1755663_1756587_-\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
WP_015825650.1\|1757473_1758571_-	prephenate dehydrogenase	NA	NA	NA	NA
WP_015825651.1\|1758573_1759872_-	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_003645964.1\|1759885_1760413_-	amino acid biosynthesis protein	NA	NA	NA	NA
WP_003640721.1\|1760421_1761591_-	chorismate synthase	NA	NA	NA	NA
WP_015825652.1\|1761583_1763038_-	MFS transporter	NA	NA	NA	NA
WP_003640723.1\|1763686_1764040_-	30S ribosome-binding factor RbfA	NA	NA	NA	NA
WP_003645962.1\|1764062_1766639_-	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	9.6e-21	23.3
WP_003640725.1\|1766653_1766959_-	hypothetical protein	NA	NA	NA	NA
WP_003640726.1\|1766948_1767248_-	YlxR family protein	NA	NA	NA	NA
WP_163627295.1\|1767292_1768510_-	transcription termination/antitermination protein NusA	NA	NA	NA	NA
WP_003640728.1\|1768530_1769007_-	ribosome maturation factor RimP	NA	NA	NA	NA
WP_003640729.1\|1769302_1773616_-	DNA polymerase III subunit alpha	A0A1X9SH08	Bradyrhizobium_phage	1.0e-14	34.0
WP_003640732.1\|1774109_1775819_-\|tRNA	proline--tRNA ligase	NA	NA	NA	NA
WP_003640733.1\|1775858_1777136_-\|protease	RIP metalloprotease RseP	NA	NA	NA	NA
WP_003640734.1\|1777173_1777959_-	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_015825653.1\|1777974_1778754_-	isoprenyl transferase	R9W0U9	Flavobacterium_phage	1.1e-23	43.1
WP_003640736.1\|1778873_1779437_-	ribosome recycling factor	NA	NA	NA	NA
WP_003640737.1\|1779438_1780161_-	UMP kinase	NA	NA	NA	NA
WP_003644498.1\|1780360_1781239_-	elongation factor Ts	NA	NA	NA	NA
1781123:1781140	attL	NA	NA	NA	NA
WP_003640739.1\|1781341_1782145_-	30S ribosomal protein S2	NA	NA	NA	NA
WP_003640740.1\|1782369_1783092_+	HAD family hydrolase	NA	NA	NA	NA
WP_003640741.1\|1783380_1784379_-	D-2-hydroxyacid dehydrogenase	M1HKI4	Acanthocystis_turfacea_Chlorella_virus	2.3e-47	34.9
WP_053267827.1\|1784463_1784769_-	GIY-YIG nuclease family protein	NA	NA	NA	NA
WP_015825656.1\|1784752_1785511_-\|tRNA	tRNA1(Val) (adenine(37)-N6)-methyltransferase	NA	NA	NA	NA
WP_025015626.1\|1785622_1786258_+	1-acyl-sn-glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
WP_163627297.1\|1786315_1786546_-	YneF family protein	NA	NA	NA	NA
WP_003644501.1\|1786649_1786889_-	DUF896 domain-containing protein	NA	NA	NA	NA
WP_003640747.1\|1787040_1787673_+	transcriptional repressor LexA	A0A1B2APZ1	Phage_Wrath	2.3e-16	56.2
WP_079994873.1\|1787737_1787923_-	hypothetical protein	NA	NA	NA	NA
WP_163627299.1\|1788228_1788858_+	hypothetical protein	NA	NA	NA	NA
WP_015825659.1\|1788907_1790077_-	hydroxymethylglutaryl-CoA synthase	NA	NA	NA	NA
WP_163627301.1\|1790112_1790505_-	hypothetical protein	NA	NA	NA	NA
WP_063486060.1\|1790668_1791061_+	hypothetical protein	NA	NA	NA	NA
WP_003640752.1\|1791506_1792448_+	glycosyltransferase family 2 protein	V9QJB1	Oenococcus_phage	2.4e-78	49.0
WP_003640755.1\|1793282_1793666_+	hypothetical protein	O48432	Lactobacillus_phage	4.7e-09	27.4
WP_079994875.1\|1793810_1795367_+	DUF4428 domain-containing protein	NA	NA	NA	NA
WP_049821964.1\|1795704_1796034_+	hypothetical protein	NA	NA	NA	NA
WP_079994877.1\|1796428_1796686_-\|transposase	IS3 family transposase	A0A0C5AEA5	Paenibacillus_phage	7.6e-11	42.7
WP_015825666.1\|1796817_1797234_-\|transposase	IS3 family transposase	A0A0C5AC89	Paenibacillus_phage	9.1e-06	35.0
WP_033608763.1\|1797293_1797761_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_077726998.1\|1798008_1798398_+\|transposase	transposase	NA	NA	NA	NA
WP_010620880.1\|1798750_1799776_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	2.3e-42	36.1
WP_163627303.1\|1799981_1801145_+\|integrase	site-specific integrase	E9LUK6	Lactobacillus_phage	4.3e-61	38.2
1807971:1807988	attR	NA	NA	NA	NA

DBSCAN-SWA_5

2088477 : 2095555

Lactobacillus_phage(40.0%)

capsid,head,portal,terminase,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_027823052.1\|2088477_2088747_-\|head,tail	phage gp6-like head-tail connector protein	NA	NA	NA	NA
WP_163627350.1\|2089156_2090698_-\|capsid	phage major capsid protein	B8R651	Lactobacillus_phage	2.0e-45	26.0
WP_163627352.1\|2090694_2091795_-\|portal	phage portal protein	A0A2H4J9Q5	uncultured_Caudovirales_phage	6.7e-48	34.0
WP_072535853.1\|2091795_2091996_-	hypothetical protein	NA	NA	NA	NA
WP_163627354.1\|2091949_2093653_-\|terminase	terminase large subunit	A0A2H4JBN3	uncultured_Caudovirales_phage	3.2e-121	40.3
WP_069137354.1\|2093649_2094123_-\|terminase	phage terminase small subunit P27 family	NA	NA	NA	NA
WP_163627356.1\|2094834_2095224_-	HNH endonuclease	A0A1J0MFT4	Staphylococcus_phage	1.0e-19	45.6
WP_163627358.1\|2095216_2095555_-\|head	phage head closure protein	A0A2P0ZLF0	Lactobacillus_phage	2.5e-09	36.6

DBSCAN-SWA_6

2305845 : 2314359

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003645867.1\|2305845_2306424_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.3e-21	33.9
WP_070083515.1\|2306416_2307442_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F760	Synechococcus_phage	2.4e-60	41.0
WP_003642591.1\|2307438_2308893_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	2.5e-50	34.0
WP_003645864.1\|2308877_2311097_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	4.5e-144	39.3
WP_163627707.1\|2311089_2311767_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_003642588.1\|2311769_2312024_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_003642587.1\|2312025_2312757_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4SM18	Cyanophage	1.6e-37	37.3
WP_015380738.1\|2312759_2313890_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_003642585.1\|2313873_2314359_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	2.3e-16	41.0

Anti-CRISPR protein detection

Acr_ID: NZ_CP048921.1|WP_163627186.1|1353320_1353728_+|HK97-gp10-family-phage-protein

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Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_CP048921.1|WP_163627186.1|1353320_1353728_+|HK97-gp10-family-phage-protein

1353320_1353728_+

135 aa aa

1304314-1393626

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP048921_1	TypeII	1.9\|115633\|30\|NZ_CP048921\|PILER-CR,CRISPRCasFinder,CRT	115633-115662	30	1370326-1370297	2

1. spacer 1.9|115633|30|NZ_CP048921|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP048921 position: 1370326-1370297, mismatch: 2

ctagtacctgttgaatcaaaacgatcagca	CRISPR spacer
ctagtacctgttgaatcaaaacaatcaaca	Protospacer
**********************.****.**

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP048921

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information