CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP047585	Lactobacillus fermentum strain AGR1487 chromosome, complete genome	2 crisprs	cas14j,cas3,DEDDh,WYL,cas2,csa3,DinG,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas14k	0	17	12	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP047585_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047585_1

1253506-1255242

TypeI-E

Consensus_repeat	Method
GGATCACCCCCATATACATGGGGAGCAC	CRISPRCasFinder
GGATCACCCCCATATACATGGGGAGCAC	CRT
GGATCACCCCCATATACATGGGGAGCAC	PILER-CR

28 spacers

DEDDh,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of NZ_CP047585_1

>merge|NZ_CP047585|1|1253506-1255242|CRISPRCasFinder,CRT,PILER-CR
GGATTACCCCCATTTGAATGGGGAAACACGAGGCACACGGAGACAGGGATCCCGGCAAGCAGGCTCATCCTCATATTCATGAGGAGCACCGGGGATGGCGATCAGCCGCTTCCACATGTCGGGATCATCCCCATACACATGGGGAGCACCGCGGATCAACGTCATTGGCCCCGACGGTGAGAGGATCACCCCCATATACATGGGGAGCACCGTCACGTGCGTTTGGGCTCGCTTAACCTGTTGGGATCACCCCCATATACATGGGGAGCACAATGGAGGCAAAAAATGAAGGAAATCAACGATAGGATCACCCCCATATACATGGGGAGCACCGGTTGGCGATTATCAATCCGCTTATATCAGCAGGATCACCCCCATATACATGGGGAGCACTTACCTCTTCGGTCTCGGTAGTAATGCCCATCAAGGATCACCCCCATATACATGGGGAGCACCCATTAGATGGATTCAAGCGCGGCGATGATCAGGGATCACCCCCATATACATGGGGAGCACCCGATTAGACGATTCTGTTTTAGTCGGCTTGAAGGATCACCCCCATATACATGGGGAGCACTTTTAAAGTCCTCGACCGTAAAGTTTTCGTTTGGGATCACCCCCATATACATGGAGAGCACCCCGGTCACCCGGCCATAATTCTACTGTCTCCACGGGATCACCCCCATATACATGGGGAGCACCTTACGCTGCCTAATCAGTTTTGCTTGTGCACGGGATCACCCCCATATACATGGGGAGCACGATTAGTATCGCCGGTCATAATGGCCGGCTTTAGGATCACCCCCATATACATGGGGAGCACCACTTTTGTATTTCTGCTTCTTGTCGCTAGCCGGGATCACCCCCATATACATGGGGAGCACGTATTGGTTGTTGTAGTTTTGACGGTTGTTTAAGGATCACCCCCATATACATGGGGAGCACGCCGAGACAGTGTGTGTCGGTTTAGTGATGCTAGGATCACCCCCATATACATGGGGAGCACCCGGTTGCCGGATGCCCAACGTGTTCTACTTGGGGATCACCCCCATATACATGGGGAGCACCCAATCAATGGACGGCACCAACTGGAACCTACAGGATCACCCCCATATACATGGGGAGCACCACCTAGGCCCAGGCCCCCGACGTCCATTACAGGATCACCCCCATATACATGGGGAGCACTAGCAACGAACCCACTGGTTAGGGGTCGCTTTGGGATCACCCCCATATACATGGGGAGCACTACACTTCGGGTTCACATAGCCAGTCCCTTGCGGGATCACCCCCATATACATGGGGAGCACTTAGTGGGAAGGCGTTCATTCCGGACGCGGCAAGGATCACCCCCATATACATGGGGAGCACAACTTGGTAATCGAACGGGCGAACAACCGTGCGGGATCACCCCCATATACATGGGGAGCACACGCCAACGATTGACCAGACAACCGGCCACTGGGGATCACCCCCATATACATGGGGAGCACTCCACCGGTTCAATCACAATTAACTATCGTTCGGGATCACCCCCATATACATGGGGAGCACCAGGCTGGAAAGCCCGTGCTAAGCTGTCGTAGAGGATCACCCCCATATACATGGGGAGCACCAGCTCGGTTAGAGTCCTTAGCTGTATGGCTGAGGATCACCCCCATATACATGGGGAGCACTTTCACCGACGATTCGGAAGGCGCGGCCGGTGGGGATCACCCCCATATACATGGGGAGCAC

>NZ_CP047585|1|1|1253506-1255242|CRISPRCasFinder
GGATTACCCCCATTTGAATGGGGAAACA	CGAGGCACACGGAGACAGGGATCCCGGCAAGCA
GGCTCATCCTCATATTCATGAGGAGCAC	CGGGGATGGCGATCAGCCGCTTCCACATGTCG
GGATCATCCCCATACACATGGGGAGCAC	CGCGGATCAACGTCATTGGCCCCGACGGTGAGA
GGATCACCCCCATATACATGGGGAGCAC	CGTCACGTGCGTTTGGGCTCGCTTAACCTGTTG
GGATCACCCCCATATACATGGGGAGCAC	AATGGAGGCAAAAAATGAAGGAAATCAACGATA
GGATCACCCCCATATACATGGGGAGCAC	CGGTTGGCGATTATCAATCCGCTTATATCAGCA
GGATCACCCCCATATACATGGGGAGCAC	TTACCTCTTCGGTCTCGGTAGTAATGCCCATCAA
GGATCACCCCCATATACATGGGGAGCAC	CCATTAGATGGATTCAAGCGCGGCGATGATCAG
GGATCACCCCCATATACATGGGGAGCAC	CCGATTAGACGATTCTGTTTTAGTCGGCTTGAA
GGATCACCCCCATATACATGGGGAGCAC	TTTTAAAGTCCTCGACCGTAAAGTTTTCGTTTG
GGATCACCCCCATATACATGGAGAGCAC	CCCGGTCACCCGGCCATAATTCTACTGTCTCCACG
GGATCACCCCCATATACATGGGGAGCAC	CTTACGCTGCCTAATCAGTTTTGCTTGTGCACG
GGATCACCCCCATATACATGGGGAGCAC	GATTAGTATCGCCGGTCATAATGGCCGGCTTTA
GGATCACCCCCATATACATGGGGAGCAC	CACTTTTGTATTTCTGCTTCTTGTCGCTAGCCG
GGATCACCCCCATATACATGGGGAGCAC	GTATTGGTTGTTGTAGTTTTGACGGTTGTTTAA
GGATCACCCCCATATACATGGGGAGCAC	GCCGAGACAGTGTGTGTCGGTTTAGTGATGCTA
GGATCACCCCCATATACATGGGGAGCAC	CCGGTTGCCGGATGCCCAACGTGTTCTACTTGG
GGATCACCCCCATATACATGGGGAGCAC	CCAATCAATGGACGGCACCAACTGGAACCTACA
GGATCACCCCCATATACATGGGGAGCAC	CACCTAGGCCCAGGCCCCCGACGTCCATTACA
GGATCACCCCCATATACATGGGGAGCAC	TAGCAACGAACCCACTGGTTAGGGGTCGCTTTG
GGATCACCCCCATATACATGGGGAGCAC	TACACTTCGGGTTCACATAGCCAGTCCCTTGCG
GGATCACCCCCATATACATGGGGAGCAC	TTAGTGGGAAGGCGTTCATTCCGGACGCGGCAA
GGATCACCCCCATATACATGGGGAGCAC	AACTTGGTAATCGAACGGGCGAACAACCGTGCG
GGATCACCCCCATATACATGGGGAGCAC	ACGCCAACGATTGACCAGACAACCGGCCACTGG
GGATCACCCCCATATACATGGGGAGCAC	TCCACCGGTTCAATCACAATTAACTATCGTTCG
GGATCACCCCCATATACATGGGGAGCAC	CAGGCTGGAAAGCCCGTGCTAAGCTGTCGTAGA
GGATCACCCCCATATACATGGGGAGCAC	CAGCTCGGTTAGAGTCCTTAGCTGTATGGCTGA
GGATCACCCCCATATACATGGGGAGCAC	TTTCACCGACGATTCGGAAGGCGCGGCCGGTGG
GGATCACCCCCATATACATGGGGAGCAC

>NZ_CP047585|1|1|1253567-1255242|CRT
GGCTCATCCTCATATTCATGAGGAGCAC	CGGGGATGGCGATCAGCCGCTTCCACATGTCG
GGATCATCCCCATACACATGGGGAGCAC	CGCGGATCAACGTCATTGGCCCCGACGGTGAGA
GGATCACCCCCATATACATGGGGAGCAC	CGTCACGTGCGTTTGGGCTCGCTTAACCTGTTG
GGATCACCCCCATATACATGGGGAGCAC	AATGGAGGCAAAAAATGAAGGAAATCAACGATA
GGATCACCCCCATATACATGGGGAGCAC	CGGTTGGCGATTATCAATCCGCTTATATCAGCA
GGATCACCCCCATATACATGGGGAGCAC	TTACCTCTTCGGTCTCGGTAGTAATGCCCATCAA
GGATCACCCCCATATACATGGGGAGCAC	CCATTAGATGGATTCAAGCGCGGCGATGATCAG
GGATCACCCCCATATACATGGGGAGCAC	CCGATTAGACGATTCTGTTTTAGTCGGCTTGAA
GGATCACCCCCATATACATGGGGAGCAC	TTTTAAAGTCCTCGACCGTAAAGTTTTCGTTTG
GGATCACCCCCATATACATGGAGAGCAC	CCCGGTCACCCGGCCATAATTCTACTGTCTCCACG
GGATCACCCCCATATACATGGGGAGCAC	CTTACGCTGCCTAATCAGTTTTGCTTGTGCACG
GGATCACCCCCATATACATGGGGAGCAC	GATTAGTATCGCCGGTCATAATGGCCGGCTTTA
GGATCACCCCCATATACATGGGGAGCAC	CACTTTTGTATTTCTGCTTCTTGTCGCTAGCCG
GGATCACCCCCATATACATGGGGAGCAC	GTATTGGTTGTTGTAGTTTTGACGGTTGTTTAA
GGATCACCCCCATATACATGGGGAGCAC	GCCGAGACAGTGTGTGTCGGTTTAGTGATGCTA
GGATCACCCCCATATACATGGGGAGCAC	CCGGTTGCCGGATGCCCAACGTGTTCTACTTGG
GGATCACCCCCATATACATGGGGAGCAC	CCAATCAATGGACGGCACCAACTGGAACCTACA
GGATCACCCCCATATACATGGGGAGCAC	CACCTAGGCCCAGGCCCCCGACGTCCATTACA
GGATCACCCCCATATACATGGGGAGCAC	TAGCAACGAACCCACTGGTTAGGGGTCGCTTTG
GGATCACCCCCATATACATGGGGAGCAC	TACACTTCGGGTTCACATAGCCAGTCCCTTGCG
GGATCACCCCCATATACATGGGGAGCAC	TTAGTGGGAAGGCGTTCATTCCGGACGCGGCAA
GGATCACCCCCATATACATGGGGAGCAC	AACTTGGTAATCGAACGGGCGAACAACCGTGCG
GGATCACCCCCATATACATGGGGAGCAC	ACGCCAACGATTGACCAGACAACCGGCCACTGG
GGATCACCCCCATATACATGGGGAGCAC	TCCACCGGTTCAATCACAATTAACTATCGTTCG
GGATCACCCCCATATACATGGGGAGCAC	CAGGCTGGAAAGCCCGTGCTAAGCTGTCGTAGA
GGATCACCCCCATATACATGGGGAGCAC	CAGCTCGGTTAGAGTCCTTAGCTGTATGGCTGA
GGATCACCCCCATATACATGGGGAGCAC	TTTCACCGACGATTCGGAAGGCGCGGCCGGTGG
GGATCACCCCCATATACATGGGGAGCAC

>NZ_CP047585|1|1|1253688-1255242|PILER-CR
GGATCACCCCCATATACATGGGGAGCAC	CGTCACGTGCGTTTGGGCTCGCTTAACCTGTTG
GGATCACCCCCATATACATGGGGAGCAC	AATGGAGGCAAAAAATGAAGGAAATCAACGATA
GGATCACCCCCATATACATGGGGAGCAC	CGGTTGGCGATTATCAATCCGCTTATATCAGCA
GGATCACCCCCATATACATGGGGAGCAC	TTACCTCTTCGGTCTCGGTAGTAATGCCCATCAA
GGATCACCCCCATATACATGGGGAGCAC	CCATTAGATGGATTCAAGCGCGGCGATGATCAG
GGATCACCCCCATATACATGGGGAGCAC	CCGATTAGACGATTCTGTTTTAGTCGGCTTGAA
GGATCACCCCCATATACATGGGGAGCAC	TTTTAAAGTCCTCGACCGTAAAGTTTTCGTTTG
GGATCACCCCCATATACATGGAGAGCAC	CCCGGTCACCCGGCCATAATTCTACTGTCTCCACG
GGATCACCCCCATATACATGGGGAGCAC	CTTACGCTGCCTAATCAGTTTTGCTTGTGCACG
GGATCACCCCCATATACATGGGGAGCAC	GATTAGTATCGCCGGTCATAATGGCCGGCTTTA
GGATCACCCCCATATACATGGGGAGCAC	CACTTTTGTATTTCTGCTTCTTGTCGCTAGCCG
GGATCACCCCCATATACATGGGGAGCAC	GTATTGGTTGTTGTAGTTTTGACGGTTGTTTAA
GGATCACCCCCATATACATGGGGAGCAC	GCCGAGACAGTGTGTGTCGGTTTAGTGATGCTA
GGATCACCCCCATATACATGGGGAGCAC	CCGGTTGCCGGATGCCCAACGTGTTCTACTTGG
GGATCACCCCCATATACATGGGGAGCAC	CCAATCAATGGACGGCACCAACTGGAACCTACA
GGATCACCCCCATATACATGGGGAGCAC	CACCTAGGCCCAGGCCCCCGACGTCCATTACA
GGATCACCCCCATATACATGGGGAGCAC	TAGCAACGAACCCACTGGTTAGGGGTCGCTTTG
GGATCACCCCCATATACATGGGGAGCAC	TACACTTCGGGTTCACATAGCCAGTCCCTTGCG
GGATCACCCCCATATACATGGGGAGCAC	TTAGTGGGAAGGCGTTCATTCCGGACGCGGCAA
GGATCACCCCCATATACATGGGGAGCAC	AACTTGGTAATCGAACGGGCGAACAACCGTGCG
GGATCACCCCCATATACATGGGGAGCAC	ACGCCAACGATTGACCAGACAACCGGCCACTGG
GGATCACCCCCATATACATGGGGAGCAC	TCCACCGGTTCAATCACAATTAACTATCGTTCG
GGATCACCCCCATATACATGGGGAGCAC	CAGGCTGGAAAGCCCGTGCTAAGCTGTCGTAGA
GGATCACCCCCATATACATGGGGAGCAC	CAGCTCGGTTAGAGTCCTTAGCTGTATGGCTGA
GGATCACCCCCATATACATGGGGAGCAC	TTTCACCGACGATTCGGAAGGCGCGGCCGGTGG
GGATCACCCCCATATACATGGGGAGCAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047585.1\|WP_076811011.1\|1260158_1261823_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09729_cas8e_CAS-I-E	gnl\|CDD\|378189
NZ_CP047585.1\|WP_086031796.1\|1250142_1250256_+\|putative-metal-homeostasis-protein	unknown	unknown	unknown
NZ_CP047585.1\|WP_003683897.1\|1266254_1266614_-\|50S-ribosomal-protein-L19	unknown	unknown	gnl\|CDD\|235418
NZ_CP047585.1\|WP_076811022.1\|1252772_1253252_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047585.1\|WP_076811013.1\|1259557_1260142_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	mkCas0194_cse2gr11_CAS-I-E	gnl\|CDD\|378191
NZ_CP047585.1\|WP_163601570.1\|1261803_1264545_-\|CRISPR-associated-helicase-Cas3'	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|182031
NZ_CP047585.1\|WP_057727886.1\|1248796_1249333_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047585.1\|WP_153300415.1\|1250404_1250563_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047585.1\|WP_076811015.1\|1258448_1259549_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|378153
NZ_CP047585.1\|WP_123800243.1\|1251018_1251567_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379233
NZ_CP047585.1\|WP_057195395.1\|1249518_1249662_+\|50S-ribosomal-protein-L33	unknown	unknown	gnl\|CDD\|179075
NZ_CP047585.1\|WP_153300416.1\|1250609_1250774_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047585.1\|WP_163601568.1\|1256159_1257095_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NZ_CP047585.1\|WP_076811020.1\|1255271_1256156_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|176648
NZ_CP047585.1\|WP_086031824.1\|1264854_1266141_+\|ISL3-family-transposase	unknown	unknown	gnl\|CDD\|225995
NZ_CP047585.1\|WP_163601567.1\|1249837_1250155_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047585.1\|WP_076811016.1\|1257091_1257748_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl\|CDD\|378050
NZ_CP047585.1\|WP_163601795.1\|1251503_1252412_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP047585.1\|WP_076811024.1\|1257760_1258468_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09756_cas5_CAS-I-E	gnl\|CDD\|187886
NZ_CP047585.1\|WP_035436283.1\|1249673_1249838_+\|50S-ribosomal-protein-L32	unknown	unknown	gnl\|CDD\|234901

Protein	Function_ID	Function_description	E-value
NZ_CP047585.1\|WP_076811011.1\|1260158_1261823_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|378189	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This entry, represented by CT1972 from Chlorobaculum tepidum, is found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse1.	6.06422e-81
NZ_CP047585.1\|WP_076811016.1\|1257091_1257748_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	1.07782e-75
NZ_CP047585.1\|WP_003683897.1\|1266254_1266614_-\|50S-ribosomal-protein-L19	gnl\|CDD\|235418	PRK05338, rplS, 50S ribosomal protein L19; Provisional.	9.14881e-68
NZ_CP047585.1\|WP_163601570.1\|1261803_1264545_-\|CRISPR-associated-helicase-Cas3'	gnl\|CDD\|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	2.27295e-83
NZ_CP047585.1\|WP_076811015.1\|1258448_1259549_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	4.94996e-141
NZ_CP047585.1\|WP_123800243.1\|1251018_1251567_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|379233	pfam13518, HTH_28, Helix-turn-helix domain. This helix-turn-helix domain is often found in transposases and is likely to be DNA-binding.	3.03661e-05
NZ_CP047585.1\|WP_057195395.1\|1249518_1249662_+\|50S-ribosomal-protein-L33	gnl\|CDD\|179075	PRK00595, rpmG, 50S ribosomal protein L33; Validated.	1.01153e-10
NZ_CP047585.1\|WP_163601568.1\|1256159_1257095_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	7.72179e-132
NZ_CP047585.1\|WP_076811020.1\|1255271_1256156_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|176648	cd06127, DEDDh, DEDDh 3'-5' exonuclease domain family. DEDDh exonucleases, part of the DnaQ-like (or DEDD) exonuclease superfamily, catalyze the excision of nucleoside monophosphates at the DNA or RNA termini in the 3'-5' direction. These proteins contain four invariant acidic residues in three conserved sequence motifs termed ExoI, ExoII and ExoIII. DEDDh exonucleases are classified as such because of the presence of specific Hx(4)D conserved pattern at the ExoIII motif. The four conserved acidic residues are clustered around the active site and serve as ligands for the two metal ions required for catalysis. Most DEDDh exonucleases are the proofreading subunits (epsilon) or domains of bacterial DNA polymerase III, the main replicating enzyme in bacteria, which functions as the chromosomal replicase. Other members include other DNA and RNA exonucleases such as RNase T, Oligoribonuclease, and RNA exonuclease (REX), among others.	3.03071e-43
NZ_CP047585.1\|WP_086031824.1\|1264854_1266141_+\|ISL3-family-transposase	gnl\|CDD\|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	6.23103e-65
NZ_CP047585.1\|WP_076811013.1\|1259557_1260142_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|378191	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family of proteins, represented by CT1973 from Chlorobaculum tepidum, is encoded by genes found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse2.	5.54216e-24
NZ_CP047585.1\|WP_163601795.1\|1251503_1252412_+\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	5.90658e-34
NZ_CP047585.1\|WP_076811024.1\|1257760_1258468_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187886	cd09756, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	2.00501e-51
NZ_CP047585.1\|WP_035436283.1\|1249673_1249838_+\|50S-ribosomal-protein-L32	gnl\|CDD\|234901	PRK01110, rpmF, 50S ribosomal protein L32; Validated.	1.04043e-16

>NZ_CP047585.1|WP_076811022.1|1252772_1253252_-|hypothetical-protein
MRKKVQQIGNQQRHRFRAKFCRLGYKVSYGHFKPTLLLTEVELIDDMEKPQVVTSHLWFNYTTGFQRLGQLQPGDVILFNARVHQYRKGYFTAKQEVDYNLSHPSKVGLASGQKRPLVPEDNVALIGMIMMQNKDYYLANDRPYEPFYVSRYQDWLQKG
>NZ_CP047585.1|WP_163601795.1|1251503_1252412_+|IS3-family-transposase
MDRNKQPGGEAAKRYQAVQEMTSSGEYTVSETARAAGISRQAYYKWLNRRLSLREQQEREVLEEIKRIEKRHQDSVGYDKMVRLLNKEGRLSYRVGIKRVSRIMKINGIRADYRQPKKDRQGAKQTYQDENLLNRQFKQEKPNQVWVTDTTELTYGAANKVRLHAILDLYGQRPAAWLISPTETREAAIKVFNQAAKASGTTPEMIHTDRGAAYTSTNYNEALRQEKVRHSLSAPGTPADNAVMENWWADLKSIWLEHRPKAQTLAELQEQVRAGIMYFTNQFISAKRNDQPVAEYYHDLVG
>NZ_CP047585.1|WP_123800243.1|1251018_1251567_+|helix-turn-helix-domain-containing-protein
MTFEAIFMKITYSTTTKLRAVHDYRNHRLPTKEILLKYDIRGLSQLRNWVILYNNGKEPVRKRVRKMGRKVSYDEKIEIVKWVLKHNHDYKQAAQKFDITYSRAYAWTQKYEQANDWTALKDRRGKTRGRQPADREEQLLKEIRDLKAKLREREVQIAFSKKLIEISNREVKRPNDIKRFKK
>NZ_CP047585.1|WP_153300416.1|1250609_1250774_-|hypothetical-protein
MKKRKKYSLKEHYNRLMEKLFLEGEEEPDYLVENFFSMPVLFFGLRIFCLFFHP
>NZ_CP047585.1|WP_153300415.1|1250404_1250563_-|hypothetical-protein
MKDHLLKWCAGSLQIDFRQEEGRKLTLGFKIELGCIFAVFFGGLVYWWVKVH
>NZ_CP047585.1|WP_086031796.1|1250142_1250256_+|putative-metal-homeostasis-protein
MEKLDYSSALRRLKSPNIKTRKRALKTIKQLKAQKNK
>NZ_CP047585.1|WP_163601567.1|1249837_1250155_+|hypothetical-protein
MSASYTDQEVIALIGRVLNHYHLSGEHFLFNRTATGLEVLTTPNDESWLLVSLLGWLQADFDLTFLDGAGHPVDFCDHRALMFTIRSVVEDAINSLLPKDDQWKN
>NZ_CP047585.1|WP_035436283.1|1249673_1249838_+|50S-ribosomal-protein-L32
MATPAHRTSKTKKRMRRGHIKLNVPNVRLDPATGEYTLPHHVSPSGQYKGRSVK
>NZ_CP047585.1|WP_057195395.1|1249518_1249662_+|50S-ribosomal-protein-L33
MRRPIVLFCSQTGERYLTTKNKANTPDRLRLLKYSAKLRRRVWFVEE
>NZ_CP047585.1|WP_057727886.1|1248796_1249333_-|hypothetical-protein
MNRQQEAELQQRIKKGIQFPEELFKMAEQTGWTIPDYQRLKEHRQKGWPLLKADIANLEAIANGREIEEPRRPSSTVRIERPAKKKRSTATKAEANAKQAARDRLAKMLRRYNGLVASGESLGVMENERDRRWMHIAETVLNDAEATTRALSSQANKIETKIERIEERLLRRQERYYY
>NZ_CP047585.1|WP_076811020.1|1255271_1256156_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MIVIALSRVPASLRGDLTKWCQEIQTGIYVGRFSARIRDLLWERIQKNIGSGEATIVYTTNNELGYAFRSTRADREVVNYDGIPLLMHLEKPPSSIKCGFSDAARFHRAKQMRTGSGKGTEMTRKVVALDIETTGLDSATDEIISIGAVKSTNGEEIERFYRIIQPDKVISPKITDLTGLSQQKVEQEGISLEAALTDLRDFIGRFIVVGYNVAFDWGFIERGYDKVGQDRLGNRIIDLLKVVRQKEVFLDNFRFETVLKYYQIENQDQHNSLADADATIKLMTKLIEKGFLKI
>NZ_CP047585.1|WP_163601568.1|1256159_1257095_-|type-I-E-CRISPR-associated-endonuclease-Cas1
MKSGMGAEKPKLTELSRTSDRISFLYLEHAKINRQDSAIKVMDARGIVFVPVALISVLLLGPGVDVAHRAMELMGDSGLAVVWVGEYGVRQYAHGRTLNHSSRLLEKQAKLVSNVRSRVAVARKMYQMRFPNEDVTKLTMQQLRGKEGSRVRKVYRKLSNETGVAWNGREYNVDNFDEGTPINKALTAANQTLYGLSYSVVAALGASPGLGFIHTGHDLAFIYDFADIYKANYSIPISFEMTAKYGDEDIARTRQAMRDAFRDGKLLKQMVHDLKFLFEVEDDQDLEFMSLWDDKEGMQKFGVQYHEIGEE
>NZ_CP047585.1|WP_076811016.1|1257091_1257748_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSRVEVDTKNRQKISDLTHLGAYHSWVEDSFPREVVKGERKRHLWRLDQVQGKEYLLVLSDDQPNMNRLEKYGVPGSAQSKIYDQFLSQIQTGKVMRFRLTANPVHRVTEPGEKVGRVYPHVTIAQQEKWLIDRAERNGFTLLTTADGYQFDVVGRDRPQLLHKGQRRVKLNRVSYEGLLKVSDEDLFKKLLVNGIGKEKAYGMGLMTVIPVNEKA
>NZ_CP047585.1|WP_076811024.1|1257760_1258468_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MKTLTVNLTGPLQSYGNEATFERRTTYHYPSKSAVIGMIAAGLGYRRDDQRIESLNKLGIAVRIDQRGKIMTDFHTVRPQNAKNSKLTYRDYLQDAVFVVAIGSEDDNLIGQIKYALRHPKFQLFLGRRANVPAGVLRIEEFDTDPMTVLKELPWQASDWFKKRMKKELYSAEVVADWGLEKGADRNLIQVKDQAGSFNVQHRYHKYRPAIRTFVTLKNNMYQENSGEHDVWSSI
>NZ_CP047585.1|WP_076811015.1|1258448_1259549_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MMKNLYLDINVLQTVPSSNINRDDTGTPKTAIYGGVTRSRVSSQSWKRVMRQAFMTDSEGAEWLNSHRTKHAAKLLAGRIKKLSDGLSDEEALEKALEAFNTTKVKPKKDKKTGEYLTGALLQLSNGQLDKLAHYVLSHDELDTKEIKETLMEKSSLDLALFGRMVADDPELNVDAASQVAHAISTHAIVPEYDFYTAIDDDKEDSQAGSAMMGTLAYNSSTLYRYANVNINELMHNLGSTELTIEGVKLFVKEFMLTMPTGKENTFANKTLPQYVMITLREDTPVNLVSAFEESVKSNHGYVEESIERLEKEYSDTLKLVEQPIYTGVLTTKQSNLNQVANTEELLDQVAKFVSEKVVDDENVNG
>NZ_CP047585.1|WP_076811013.1|1259557_1260142_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSHISKTVAKIIHQLCNDGDLDKGTLAKLRTANSLLSRDATAIWPLLFENIEDKQDLSQTGEPSFAENAIFAALRAYAIYQQGTEESVFKHSDDWRENHSLFQAFGRLRSDPDFTDSLDKRVSNVLTSLNFQSAENSITQLVRILKSKGQGGQIDFAQLGEDLYRFQFSSESARQVTLKWGQDYYWNNLKDNQE
>NZ_CP047585.1|WP_076811011.1|1260158_1261823_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MKNRHFNLITEPWIKVLDENYQELTVSMEEVLKNARHYRQLAGEMRSQDLVILRLLLAVLLSVYQRVNADGEPYEGLTIDDAWQVEVDSDLDFEDLIEEMQETWQTLYEGGEFSQAVFDYLKAYEDRFDFFGEHAFYQVSREFYDAHVPAKNQVAKGTGTVAIKQINRNISESGNSIAVFTPRTNTFKNQLSIDELVRWVLTYQNYTGVTDKTKVNRADKFSVSSGWLYNLYPVYAQGTNLFETLLLNLTLFEDEQDKYSQPKPVWEWATKRYLKGRIDETVPDNLPELYTLWSRMLHIEWEEGTPTIFTAGLPKVSNVNVFLEPMTTWRQDKEGYKPRVKRLDNLGTAMWRNFGDYVGTDDEENRVPGIVWWLNFLTEEGLLAQEANIDLASAVMISDGKGSSQMPAAESVDDFTIRADVLFDPDPLAARRWPRRIEEVIELTKKVGGTLYYFAKEVAELRDSNGSGSFANRISAEFYDQLNEPFLGWLASLRNDQDRDEKILEWKKALHSLVMQTARKLVQESSPTEMRGKDSTNIFTLYNATQLKIRKQLS
>NZ_CP047585.1|WP_163601570.1|1261803_1264545_-|CRISPR-associated-helicase-Cas3'
MKELSKQVKALWGKKSNVDGQELWQPLVVHLLDTKNVINWLYGHWLTDGQRKAVQGGLSEEAGQQLAGFLGAVHDLGKATPVFQIKKSYNGDQDLDDQLMEHLIQVGFDQLGDLILASPRESPHALAGEALLEQFGIDQTVGAIIGGHHGKPQSNVPRTEINDHTKNYWQVDNFVKAREGNWLKVQRELFNFCLQECGYQSASDVPTNLTQSQAVLLEGLLIMADWLASTEYLGDDRSKPLFPLILLHNSMEDLDLSARFQRAILTWRVEDQWFPEQITDIDEQFQKRWGFKPRPVQRQMDQVIQDATDPGIIIIELEPGAGKTEIALEAVEQLAYTNGEQGLFFGLPTQATSNAMFDRVTDWLAKVAKDDDAKLGIKLMHSKAEFNPTYADLKIPQAHNVEEEGSVTVNSWFSGKKSILEEFSIGTIDHLLLMGLKQKHLFLRHLGMSGKVVVIDEVHAYDAYMDSYLTKALEWLGAYHVPVIALSATLPIATRSALIEAYCKGKYGKKKVEGAPSWDKNQAYPLISVLDGKRLVQKSDFMRNTEKRDVEVERLSVEEEGLIKAVLEAVEDGGVAGVIVNTVKRAQMIASQIPKGIPKLILHSAFLAPDRAEIETKLQGLIGKYGKRPKKMIIIGTQVLEQSLDIDFDIMFTDIAPMDLLIQRIGRLHRHDIQRPSKLVTPQVKIMGINDYGDYGSANEAIYSKYLLMKTDQYLPEQLTIPDDISPLVQATYRDDGEMEPDLREAKRVFDVKHKEELDKAEKFQIKSPKQRKSLHGWLDSELVDANKDEVCAQAAVRDIQETLEVLMVKQVKGDYYLLDGQQLEEVDSKMIAQQLIRIPAAVTPRIDKSIELLETQTAKNFPDWQADPWLKGALVVVLDEQNSAELGNWRIHYSRKFGLSYEKADDDEKQAF
>NZ_CP047585.1|WP_086031824.1|1264854_1266141_+|ISL3-family-transposase
MTDYIKNILQIKDPNLHFTDVVFENNDGRETQVFIGTVSLKLDRCPHCGFADTFIKNGHSYQTIKYLSINESCPTMLRIGKQRLRCKNCQDSFMAKTNVVDKYCSIAKAVKHKALTMLESNVSQKDVSKFTGVSPSTIGRLLDSDQALLRFNSRTLPTNIAIDEFRGPQGKYCFIIVDNDTSQIYQILPDRLKSSITHYFDRFSLKERKRVKSVSTDLNSYYQGLVRRYFPNAKLVVDRFHIVSMLTRAFNQVRVAVMKQFDPNTREYRALKNSWRLYLLKSTSLNYTKEYYDRHLRQKVTMAERVGIGLDLDPQLAAGYELLQGAMTALEEHDVDQLMDLLFTKWDVPAPFQTVLKTLRKNSEGVYNATVLPYSNGRVEGINRMIKLIQRTAYGFTNFGHFIARIRLHQMGTEAEKRRRQVQAPAAA
>NZ_CP047585.1|WP_003683897.1|1266254_1266614_-|50S-ribosomal-protein-L19
MRQNQLIEKVTAGQLRSDIPAFRAGDTVRVHALIVEGTRERVQIFEGVVIKRHGAGISATYTVRKISNGIGVERTFPLHSPRVEKIEVVRYGRVRRAKLYYLRERTGKSARIAERRRDK

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Crispr_ID: NZ_CP047585_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP047585_2

1671612-1671694

Orphan

Consensus_repeat	Method
GCTCCCCAACCGCAGGCCTAGTGCCTA	CRISPRCasFinder

1 spacers

WYL

The CRISPR arrays of NZ_CP047585_2

>merge|NZ_CP047585|2|1671612-1671694|CRISPRCasFinder
GCTCCCCAACCGCAGGCCTAGTGCCTATGGTTGGTCCACACTTCCAAAGATAACGCGCTCCCCAACCACAGGCCTAGTGCCTA

>NZ_CP047585|2|2|1671612-1671694|CRISPRCasFinder
GCTCCCCAACCGCAGGCCTAGTGCCTA	TGGTTGGTCCACACTTCCAAAGATAACGC
GCTCCCCAACCACAGGCCTAGTGCCTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP047585.1\|WP_049182600.1\|1667698_1669147_+\|multidrug-efflux-MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_CP047585.1\|WP_049182593.1\|1660663_1661212_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047585.1\|WP_003681394.1\|1671777_1672254_-\|S-ribosylhomocysteine-lyase	unknown	unknown	gnl\|CDD\|179399
NZ_CP047585.1\|WP_057727408.1\|1673822_1674197_-\|HAD-hydrolase-like-protein	unknown	unknown	gnl\|CDD\|319800
NZ_CP047585.1\|WP_062813650.1\|1679717_1680140_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133384
NZ_CP047585.1\|WP_057727403.1\|1679017_1679476_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP047585.1\|WP_062813653.1\|1663534_1666531_-\|DEAD/DEAH-box-helicase	unknown	unknown	gnl\|CDD\|223989
NZ_CP047585.1\|WP_057727405.1\|1676309_1676831_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP047585.1\|WP_163601803.1\|1670431_1671160_+\|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl\|CDD\|379100
NZ_CP047585.1\|WP_062813652.1\|1669148_1669907_+\|DUF4811-domain-containing-protein	unknown	unknown	gnl\|CDD\|374344
NZ_CP047585.1\|WP_049182599.1\|1667012_1667558_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379534
NZ_CP047585.1\|WP_163601706.1\|1672314_1673430_-\|5-methyltetrahydropteroyltriglutamate---homocysteine-S-methyltransferase	unknown	unknown	gnl\|CDD\|180482
NZ_CP047585.1\|WP_163601704.1\|1661392_1662424_+\|lactonase-family-protein	unknown	unknown	gnl\|CDD\|378416
NZ_CP047585.1\|WP_163601705.1\|1662630_1663218_-\|phosphatase-PAP2-family-protein	unknown	unknown	gnl\|CDD\|239486
NZ_CP047585.1\|WP_062813651.1\|1674245_1674476_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|162788
NZ_CP047585.1\|WP_057727406.1\|1675694_1676291_+\|mannosyl-glycoprotein-endo-beta-N-acetylglucosamidase	unknown	unknown	gnl\|CDD\|224619
NZ_CP047585.1\|WP_049182596.1\|1663214_1663526_-\|nucleotide-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|212144
NZ_CP047585.1\|WP_062813649.1\|1682154_1682904_+\|5-oxoprolinase-subunit-PxpA	unknown	unknown	gnl\|CDD\|212099
NZ_CP047585.1\|WP_057727404.1\|1677500_1679021_+\|LytTR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176454
NZ_CP047585.1\|WP_049182598.1\|1666543_1666960_-\|(deoxy)nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|239517

Protein	Function_ID	Function_description	E-value
NZ_CP047585.1\|WP_049182600.1\|1667698_1669147_+\|multidrug-efflux-MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	7.5497e-87
NZ_CP047585.1\|WP_062813652.1\|1669148_1669907_+\|DUF4811-domain-containing-protein	gnl\|CDD\|374344	pfam16069, DUF4811, Domain of unknown function (DUF4811). This family of proteins is found in bacteria. Proteins in this family are typically between 188 and 241 amino acids in length. There is a single completely conserved residue Y that may be functionally important.	2.84661e-33
NZ_CP047585.1\|WP_003681394.1\|1671777_1672254_-\|S-ribosylhomocysteine-lyase	gnl\|CDD\|179399	PRK02260, PRK02260, S-ribosylhomocysteine lyase.	5.47954e-95
NZ_CP047585.1\|WP_057727408.1\|1673822_1674197_-\|HAD-hydrolase-like-protein	gnl\|CDD\|319800	cd04305, HAD_Neu5Ac-Pase_like, human N-acetylneuraminate-9-phosphate phosphatase, Escherichia coli house-cleaning phosphatase YjjG, and related phosphatases. N-acetylneuraminate-9- phosphatase (Neu5Ac-9-Pase; E.C. 3.1.3.29) catalyzes the dephosphorylation of N-acylneuraminate 9-phosphate during the synthesis of N-acetylneuraminate; Escherichia coli nucleotide phosphatase YjjG has a broad pyrimidine nucleotide activity spectrum and functions as an in vivo house-cleaning phosphatase for noncanonical pyrimidine nucleotides. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.24791e-27
NZ_CP047585.1\|WP_062813650.1\|1679717_1680140_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133384	cd01109, HTH_YyaN, Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB. Putative helix-turn-helix (HTH) MerR-like transcription regulators of Bacillus subtilis, YyaN and YraB, and related proteins; N-terminal domain. Based on sequence similarity, these proteins are predicted to function as transcription regulators that mediate responses to stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	3.46753e-47
NZ_CP047585.1\|WP_062813651.1\|1674245_1674476_-\|hypothetical-protein	gnl\|CDD\|162788	TIGR02254, hydrolase_haloacid_dehalogenase-like_family, noncanonical pyrimidine nucleotidase, YjjG family. This HAD superfamily includes including YjjG from E. coli and YfnB from B. subtilis. YjjG has been shown to act as a house-cleaning enzyme, cleaving nucleotides with non-canonical nucleotide bases. This family is a member of the haloacid dehalogenase (HAD) superfamily of hydrolases which are characterized by three conserved sequence motifs. By virtue of an alpha helical domain in-between the first and second conserved motif, this family is a member of subfamily IA (TIGR01549).	1.44271e-12
NZ_CP047585.1\|WP_057727405.1\|1676309_1676831_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	7.01445e-07
NZ_CP047585.1\|WP_163601803.1\|1670431_1671160_+\|WYL-domain-containing-protein	gnl\|CDD\|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	5.31392e-12
NZ_CP047585.1\|WP_062813653.1\|1663534_1666531_-\|DEAD/DEAH-box-helicase	gnl\|CDD\|223989	COG1061, SSL2, DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair].	1.08339e-82
NZ_CP047585.1\|WP_049182599.1\|1667012_1667558_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|379534	pfam14278, TetR_C_8, Transcriptional regulator C-terminal region. This domain is a tetracycline repressor, domain 2, or C-terminus.	1.24604e-09
NZ_CP047585.1\|WP_163601706.1\|1672314_1673430_-\|5-methyltetrahydropteroyltriglutamate---homocysteine-S-methyltransferase	gnl\|CDD\|180482	PRK06233, PRK06233, vitamin B12 independent methionine synthase.	1.87476e-146
NZ_CP047585.1\|WP_163601704.1\|1661392_1662424_+\|lactonase-family-protein	gnl\|CDD\|378416	pfam10282, Lactonase, Lactonase, 7-bladed beta-propeller. This entry contains bacterial 6-phosphogluconolactonases (6PGL)YbhE-type (EC:3.1.1.31) which hydrolyze 6-phosphogluconolactone to 6-phosphogluconate. The entry also contains the fungal muconate lactonising enzyme carboxy-cis,cis-muconate cyclase (EC:5.5.1.5) and muconate cycloisomerase (EC:5.5.1.1), which convert cis,cis-muconates to muconolactones and vice versa as part of the microbial beta-ketoadipate pathway. Structures of proteins in this family have revealed a 7-bladed beta-propeller fold.	1.77193e-122
NZ_CP047585.1\|WP_163601705.1\|1662630_1663218_-\|phosphatase-PAP2-family-protein	gnl\|CDD\|239486	cd03392, PAP2_like_2, PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	8.51584e-24
NZ_CP047585.1\|WP_057727406.1\|1675694_1676291_+\|mannosyl-glycoprotein-endo-beta-N-acetylglucosamidase	gnl\|CDD\|224619	COG1705, FlgJ, Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion].	2.88357e-51
NZ_CP047585.1\|WP_049182596.1\|1663214_1663526_-\|nucleotide-pyrophosphohydrolase	gnl\|CDD\|212144	cd11537, NTP-PPase_RS21-C6_like, Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in mouse RS21-C6 protein and its homologs. RS21-C6 proteins, highly expressed in all vertebrate genomes and green plants, act as house-cleaning enzymes, removing 5-methyl dCTP (m5dCTP) in order to prevent gene silencing. They show significant sequence similarity to the dimeric 2-deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTP pyrophosphatase or dUTPase) and NTP-PPase MazG proteins. However, unlike typical tandem-domain MazG proteins, RS21-C6 contains a single MazG-like domain and functions as a tetramer (a dimer of dimers) with a typical four-helical bundle. Divalent ions, such as Mg2+, are required for its pyrophosphatase activity. This family also includes a pyrophosphatase from Archaeoglobus fulgidus (Af1178). Although its biological role remains unclear, Af1178 shows significant sequence similarity to the mouse RS21-C6 protein.	8.15026e-36
NZ_CP047585.1\|WP_062813649.1\|1682154_1682904_+\|5-oxoprolinase-subunit-PxpA	gnl\|CDD\|212099	cd10787, LamB_YcsF_like, LamB/YcsF family of lactam utilization protein. The LamB/YbgL family includes the Aspergillus nidulans protein LamB, and its homologs from all three kingdoms of life. The lamb gene locates at the lam locus of Aspergillus nidulans, consisting of two divergently transcribed genes, lamA and lamB, needed for the utilization of lactams such as 2-pyrrolidinone. Both genes are under the control of the positive regulatory gene amdR and are subject to carbon and nitrogen metabolite repression. Although the exact molecular function of LamB is unknown, it might be required for conversion of exogenous 2-pyrrolidinone to endogenous GABA.	2.3992e-141
NZ_CP047585.1\|WP_057727404.1\|1677500_1679021_+\|LytTR-family-transcriptional-regulator	gnl\|CDD\|176454	cd01700, PolY_Pol_V_umuC, umuC subunit of DNA Polymerase V. umuC subunit of Pol V. Pol V is a bacterial translesion synthesis (TLS) polymerase that consists of the heterotrimer of one umuC and two umuD subunits. Translesion synthesis is a process that allows the bypass of a variety of DNA lesions. TLS polymerases lack proofreading activity and have low fidelity and low processivity. They use damaged DNA as templates and insert nucleotides opposite the lesions. Pol V, RecA, single stranded DNA-binding protein, beta sliding clamp, and gamma clamp loading complex are responsible for inducing the SOS response in bacteria to repair UV-induced DNA damage.	1.22959e-90
NZ_CP047585.1\|WP_049182598.1\|1666543_1666960_-\|(deoxy)nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|239517	cd03425, MutT_pyrophosphohydrolase, The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic pyrophosphate (PPi). This enzyme requires two divalent cations for activity; one coordinates the phosphoryl groups of the NTP/dNTP substrate, and the other coordinates to the enzyme. It also contains the Nudix motif, a highly conserved 23-residue block (GX5EX7REUXEEXGU, where U = I, L or V), that functions as metal binding and catalytic site. MutT pyrophosphohydrolase is important in preventing errors in DNA replication by hydrolyzing mutagenic nucleotides such as 8-oxo-dGTP (a product of oxidative damage), which can mispair with template adenine during DNA replication, to guanine nucleotides.	1.78482e-43

>NZ_CP047585.1|WP_163601803.1|1670431_1671160_+|WYL-domain-containing-protein
MTRPLNQLQLAEHGADEINTLLKGERHYYRPVAEPTQLAVLETFLDAVYAHKKVIVDYRKRDGSIDKDYVFTPLSIEHFDYYWYVRGYKEVDTTKGAKGDEADAARILRCDGVLSIKIGPDATKRELEGFEADRNTVIGMFKGKNHQTQTILVKADHKAAKITIDRINAEVVSYYVDQTEFPASSLAEVPDDAPVKLKSRLMLGAGLYLLLGISGIEVLEPKELRLEIIKKLSDTLARYQLD
>NZ_CP047585.1|WP_062813652.1|1669148_1669907_+|DUF4811-domain-containing-protein
MMLILLLIILFGGSFFFFANLHPHRTGAITSALFFGLSILLLVLNMGTHLGLTKTTNNNRQTIRPTSTAQGVQLLVYQPLGTTNNEQVYVYNGDQKSPLPGKRGLAKTTRVVSSVTTTNAKHATLTLTTTKYTYQNQLAKVLFAIPGTKLATTQQVAHFTVPKSWLVLSSKQATRLKQATANPANQAALKTQATAYVTAHVQSELKALAAKAQAGDQAAQAQLANQAQLTQSLTAQYQRAFTRQALLKLSSH
>NZ_CP047585.1|WP_049182600.1|1667698_1669147_+|multidrug-efflux-MFS-transporter
MNMTSSSVDVHGKAYNRILLVIVVMIGSFATVLNQTFLATALPTFMRVFDVSTATVQWLSTGFLLVNGIMIPISAWLADNVPTKRLYLITMLIFFCGTLIAFQVHSFAALLVGRLIQAVGVGVVLPLLQIMMLKIFPANQRGQAMGLAGIVVGLAPAISPTLAGYILDHGSWRILFGMLLPIIAFVLFGALFFMKDVLPGKPSQLDLWSTITSTLGFGSLLYGFSTAGNDGWGDAKVLIALAVGLVFIALFIHRQLTMERPFLDLQVFLNKDFTVGTLLSSFVNLSMVGVEMALPLYLQDLMGHSPFESGLTMLPGALLIGLMSPVTGRLFDQYGIRNLAITGFAILTLGNLPFIFLSATTPEILVVFLYAVRMFGISLVLMTTITNAMNAIPVSEFSHGTAANNTFRQITSSMVTAVIISILSNVTKAQLPGHALKSSAPLLYANRAFEATLHGYSATFLFATLFSVAGLCLALTLKPTRR
>NZ_CP047585.1|WP_049182599.1|1667012_1667558_-|TetR/AcrR-family-transcriptional-regulator
MAEKEENRRVKYTKRVIKEALIELMANRQVGEISVKKLCEQADVNRSTFYAHYGNPMDVMWELEEEVFTDLQQSVANHGQCQDKRVTLESIMQAVLEYVQERRQTFLVLFAQDNLGDFQDQLFVLTQGQKTHPKNMTQEQRDYQRRYVFYGNVAVIKSWLEKEDRESVEEMAKLIAKWMLG
>NZ_CP047585.1|WP_049182598.1|1666543_1666960_-|(deoxy)nucleoside-triphosphate-pyrophosphohydrolase
MSKQIQVVGAAILNDQNQILATQRADARVLGQQWEFPGGKIKAGETPEQALARELEEEFSVQAQVGPAVGPTFKHEYDFGTVNLTVYYVRLASEDLRLMAHGKVVWCEQTQLGKLDWAATDRQIAELIEQEDLTQLAI
>NZ_CP047585.1|WP_062813653.1|1663534_1666531_-|DEAD/DEAH-box-helicase
MHQDVNYDHLLDELGTQGSLAKEMGASLLHGYVDQDGVQPIGDFGPKLLTNQFDNQIWDQLRSELNDATEYAFAVAFVTDAMVSNLKPLFRTLAARGVKGRLLTSTYLQFNQPDMFEELLKIGNLEVRIATVKGFHQKGYLFKHRDYQTVIIGSANLTASALMKNQNYEWSLKISSLNNGEITSQIEENFEAEWRDAKPLSEDWLDGYRKAYQADHQVNRAVHDYVTPSDEPGKAQQVKPNQMQTAALNEIEALRLAGKDRGLVVSATGTGKTYLGAFDVRAAKPKRMLFLAHREQILQKSCQSFQNILGGDPANFGLYTGGARDKNAKYLFASVQTLSREEHLHRFSPDDFDYILIDEVHHAGAESYQRIMNYFTPKFFLGMTATPERSDDFNIFNLFHYNVAYEIRLQQALELNMLAPFHYVGLTDYAFADQYEEEIDQYRNRKQGSKPSRKQEQRAVELLTSKERVNYILEQTDYYGYSGPVLHGLVFCSSVAEAEALARAFTAAGHPAKALSGADNGDRRRQVVHELENGLIEYIITVDIFNEGIDIPCVNQVVFLRNTQSAIVYVQQLGRGLRKYPGKEYVEVLDFIGNYKNNYMIPIALTGDNSYSKDQARDTVDIEPTVGLSTIAFDEVAKERIYESLSKVKLDGLANLRDAYQNIKRRVGRIPMLSDFLKMDSVDPRILATVVKPRNYNRFLLKMGEPVEVTDYEDQALSLISVELLNGKRRHELILLRLLLQRSVVKEVDYVRALKEAGCYVNEATLNSVRQVLSLQYYAERAYPSRASYGGVALVNYDPDQKNYQMGEQLAQALTKRGWFYQLWSDAIETGLLRAERYQANEQFTIGERYTRRDAVRLINNPYDMNGQLVSGYRFTSEETGLKEAIIFVTYKKAKNIRKEINYNNRFINDHVLHYYTKNSDIKLDSANVVKFMGGEYKLRLFVQKSGAIDETEFYYLGTCRYLNNSVQKETQDGVPRLAMDLLLDHPVEHNRYHTFID
>NZ_CP047585.1|WP_049182596.1|1663214_1663526_-|nucleotide-pyrophosphohydrolase
MDYQEITTILRDFTAQKGWGKYHNLKDLALSVNLEASEVLEVFQWKDEQTPLTNEERDHLKEEIADTLIYLFYMCDEMGLDPYQAIAEKMKVNQTRHWKEEDQ
>NZ_CP047585.1|WP_163601705.1|1662630_1663218_-|phosphatase-PAP2-family-protein
MSVTVIPHWGAWLIGLLVLLGLLLLDLAHHGLVARFDDWAFDKMPHQPDNRFWNLVAWVGEPWAVVVYVLILTVALLVIHEEQAAAWVLWTLGIGNVLGIITKKTLKRERPGAHLEHDDGYSFPSGHVLGGMTLYLMVVELWPLWPVIVIGGLAWLLVAGSRIILRAHHVSDVAGTVLFAGAWFIVSTLLYQLIF
>NZ_CP047585.1|WP_163601704.1|1661392_1662424_+|lactonase-family-protein
MLEHYLIGTYTHHTSQGIYSVTLDTSAGRLSPTHLEIPIQKPIFMTFANNGILYTIEKLDQDHAAITSFKEEGGHFTRLSSVSAPGTTTAYLAIDEERQLLFSANYHMSTVTTYRLDGQGGMQKADQVLKVGATGPRPQQELPHVHFANLTPDRRLVICDLGMDQVNIYNLTDQGQLKLVTTHQDLPGFGDRHLAFGRDGRFMYLVGELSSKLEVLAYDQENGELSSIQTVSTIPADWIAHNGATAIHVCHSGHFVYVSNRGENTIAVFEAQPDGRVKHIQSVATAGDFPRDFSLSHDQKFMIVANQNTNDLTLMRRDPATGHLATIQTGMPCPEPVQVLYWK
>NZ_CP047585.1|WP_049182593.1|1660663_1661212_-|hypothetical-protein
MDARLIQFHITPKLEGQTQEELRQNPSGFNMEFISKEKYISENLQGVPQFRREYRHSLNHVVDQFNEYYQWHTEKAAKMKHYGDSFGRLEDLSDATKYLASLLKSEFLVPNELELIDIQIVGQFSVYESGSDTELKKQADQIREASIREMQKKMAARQPAPNQPGQPGRPVAMHFPNREPRA
>NZ_CP047585.1|WP_003681394.1|1671777_1672254_-|S-ribosylhomocysteine-lyase
MAKVESFTLDHTKVKAPYVRLITVEEGPKGDKIANYDLRLVQPNENAIPTAGLHTIEHLLAGLLRDRLDGVIDCSPFGCRTGFHLITWGEHSTTDVAKALKSSLEEIAYHTEWEDVQGTTIESCGNYRDHSLFSAKEWSKTILDQGISDQPFERHVVE
>NZ_CP047585.1|WP_163601706.1|1672314_1673430_-|5-methyltetrahydropteroyltriglutamate---homocysteine-S-methyltransferase
MTTQLHYDIVGSFLRPQALKEAREQFAAGQLSKADLTKVEDAQIKELVQKEAAAGLKVVTDGEFRRSYWHLDTFWGFGGIKHTTQTHGYFFHDEETRNDSAQVEGKIRFTGEHPDLTAFKYLKSLTDGTDLTPRQSIPSPAQCYAELYRGDENIAKLKEVYANEDDLVHDLATAYRDLILALYDAGCRDLKLDDCTWGMVVDDDFWQSMADAGFDREQLAAKYLEVNNGALVDLPADLRVSTHICRGNYHSTWAAKGGYGPVAKYVFAKENVSAFYLEFDDERSGGFEPLQEVPVGKEVVLGLVTSKQPELEAVADLVDRIKEASQYVALDDLALSTQCGFASTEEGNQLTEDQQWAKIKLVVEVAKQVWG
>NZ_CP047585.1|WP_057727408.1|1673822_1674197_-|HAD-hydrolase-like-protein
MGTQHELMPGAMAMLKQAQVQKSRLSESGLVPLFSSVLVSETVGVEKPDPVIFERFFATSEVAPEQSIMIGDGLPSDIVGAHKAHLASVWYNPRRVANTSGVTPTVTVANHQELTDLLTQWAHA
>NZ_CP047585.1|WP_062813651.1|1674245_1674476_-|hypothetical-protein
MRYQQLIFDVDNTLLNFSAGETVALTTLFEKHGIAPTPSLVAAYQRYNTSLWRQIEAGALTKDELFAKWFVTFFKE
>NZ_CP047585.1|WP_057727406.1|1675694_1676291_+|mannosyl-glycoprotein-endo-beta-N-acetylglucosamidase
MIDVKKNDDVIVIVAGIIVSLLVVLGVGIGAAYYQQTSLSQTHSAKITTKEFIKEIAPAAQAVEKKYGIPASIIIAQAGTESDWGRAKLAYKYNNLFGIKASGKTNQVKMYTKETLNGKTVTIKQYFQVYSSWKASIDAHTKLILNGTTDNPHRYRGVITKSYTKAAWALQNNGYATDPNYANELIYAIKKFKLDHYD
>NZ_CP047585.1|WP_057727405.1|1676309_1676831_+|GNAT-family-N-acetyltransferase
MNPTFTLAPATTADVLAVLEIINHAKAFLKAAGSTQWQSGYPNADTITTDIANEVGWVLKADHQVVGYAAVIVGEDPNYQEIDGAWQNTRDPYATIHRIAISNQYLGQHLGQRFFKLIIDHFAGEGVHNFRVDTFKLNQPMQHVAKSAGFEYRGIIKVVDPVDPARLAFELNL
>NZ_CP047585.1|WP_057727404.1|1677500_1679021_+|LytTR-family-transcriptional-regulator
MAQEHTYIAIDLKSFYASAECAAHGLDPLNANLVVADASRTDKTICLAVSPALKSFGVPGRPRLFEVNQQVDRVNRQRAAKFANRRLSKTRSIYKDELKRRTGLRVDFMIVPPRMRYYLQVSAKIYEIYLRFIPPEKIHVYSIDEVFIDATDYLATHHESAYALAKKMIQAIQAEFGITATAGIGTNLYLAKVAMDIVAKKIPGDADGVRIVAMTEQDYRRLLWAHQPLTDFWRVGRGYARRLEKLGLHTMGDIARCSLGTLSDPQNEEVLYREFGKHAQLLINHAWGYEAATIEDIKNYRASEHGIYSGQVLMKPYTIPQARQVISEMSADLSLQLVKRHALTNQIALHLSYDVKSISYASNYHGPIITDFYGRQVPKPDHGGAYLPDLTSSPRELRGAFLDLYDRIANRDLLIRKVTVIANHLVDEEEAAKQVRTEQLNLFEDPHQKVAEQQSAQSTRDQEHEVQELVLKLQEQYGKNAIIRAADLLDGSTTRKRNDEIGGHRA
>NZ_CP047585.1|WP_057727403.1|1679017_1679476_+|hypothetical-protein
MNKPAPDQQTATIEARLFKDTSAYQDIMDLPRPVSKNHWPLPAADHAGQFAPFAALTGYHQLINEVAERYSHKNYPDELSTKRIERKLLAIKPLLPLRLKVEYFNGDSGYYETIAGTATQLDFRRGRLMLTSKQEWELIIANLRKVTVVTRK
>NZ_CP047585.1|WP_062813650.1|1679717_1680140_-|MerR-family-transcriptional-regulator
MEAIKEHTYQIGEVARKYHLSVATLRYYDQEGLIPGLGKSASGVRQFTDENLVALDVVECLKNAGMSIKDIKVFMELVSQGDATLAERQAMFYDLKERLQAKLATLEETMKMVDFKCAYYTQAVADGTERYVKEAMHRVD
>NZ_CP047585.1|WP_062813649.1|1682154_1682904_+|5-oxoprolinase-subunit-PxpA
MTRIDLNSDLGESFGRYTIGNDDQVLGLITAANVACGFHAGDPDVMAKTVALAEAKGVAIGAHPGFPDLGGFGRRKLDMAPAEVKNMVTYQVSALMGFTKDHRLHHVKPHGALYNAAAKDLELARAICEGVARVDDQLPLYGLAGSQLLVAAKEVGLPAYSEVFADRGYQADGSLVPRSQPNAVLTDPLAVAERALSMVQTQSVTAVTGETVPLKIDTICVHGDNQAALALVDQLRQTFTANGITIQSC

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP047585_1	1.8\|1253961\|33\|NZ_CP047585\|CRISPRCasFinder,CRT,PILER-CR	1253961-1253993	33	MN830252	Lactobacillus phage JNU_P1, complete genome	28899-28931	0	1.0
NZ_CP047585_1	1.8\|1253961\|33\|NZ_CP047585\|CRISPRCasFinder,CRT,PILER-CR	1253961-1253993	33	HQ141410	Lactobacillus phage LF1, complete genome	25756-25788	0	1.0
NZ_CP047585_1	1.9\|1254022\|33\|NZ_CP047585\|CRISPRCasFinder,CRT,PILER-CR	1254022-1254054	33	MN830252	Lactobacillus phage JNU_P1, complete genome	29256-29288	0	1.0
NZ_CP047585_1	1.9\|1254022\|33\|NZ_CP047585\|CRISPRCasFinder,CRT,PILER-CR	1254022-1254054	33	HQ141410	Lactobacillus phage LF1, complete genome	26113-26145	0	1.0
NZ_CP047585_1	1.24\|1254938\|33\|NZ_CP047585\|CRISPRCasFinder,CRT,PILER-CR	1254938-1254970	33	MN830252	Lactobacillus phage JNU_P1, complete genome	25782-25814	0	1.0
NZ_CP047585_1	1.22\|1254816\|33\|NZ_CP047585\|CRISPRCasFinder,CRT,PILER-CR	1254816-1254848	33	NC_029068	Lactobacillus phage LfeSau, complete genome	15599-15631	1	0.97
NZ_CP047585_1	1.11\|1254144\|35\|NZ_CP047585\|CRISPRCasFinder,CRT,PILER-CR	1254144-1254178	35	GU323708	Lactobacillus phage phiPYB5, complete genome	31843-31877	2	0.943
NZ_CP047585_1	1.19\|1254634\|32\|NZ_CP047585\|CRISPRCasFinder,CRT,PILER-CR	1254634-1254665	32	NC_029068	Lactobacillus phage LfeSau, complete genome	14157-14188	2	0.938
NZ_CP047585_1	1.20\|1254694\|33\|NZ_CP047585\|CRISPRCasFinder,CRT,PILER-CR	1254694-1254726	33	NC_029068	Lactobacillus phage LfeSau, complete genome	15333-15365	2	0.939
NZ_CP047585_1	1.27\|1255121\|33\|NZ_CP047585\|CRISPRCasFinder,CRT,PILER-CR	1255121-1255153	33	GU323708	Lactobacillus phage phiPYB5, complete genome	18448-18480	2	0.939
NZ_CP047585_1	1.28\|1255182\|33\|NZ_CP047585\|CRISPRCasFinder,CRT,PILER-CR	1255182-1255214	33	NC_029068	Lactobacillus phage LfeSau, complete genome	17037-17069	2	0.939
NZ_CP047585_1	1.14\|1254329\|33\|NZ_CP047585\|CRISPRCasFinder,CRT,PILER-CR	1254329-1254361	33	HQ141410	Lactobacillus phage LF1, complete genome	40303-40335	3	0.909
NZ_CP047585_1	1.21\|1254755\|33\|NZ_CP047585\|CRISPRCasFinder,CRT,PILER-CR	1254755-1254787	33	NC_029068	Lactobacillus phage LfeSau, complete genome	18305-18337	3	0.909
NZ_CP047585_1	1.26\|1255060\|33\|NZ_CP047585\|CRISPRCasFinder,CRT,PILER-CR	1255060-1255092	33	NC_029068	Lactobacillus phage LfeSau, complete genome	26186-26218	3	0.909
NZ_CP047585_1	1.17\|1254512\|33\|NZ_CP047585\|CRISPRCasFinder,CRT,PILER-CR	1254512-1254544	33	MN830253	Lactobacillus phage JNU_P5, complete genome	27136-27168	4	0.879
NZ_CP047585_1	1.1\|1253534\|33\|NZ_CP047585\|CRISPRCasFinder	1253534-1253566	33	NZ_CP041164	Leisingera aquaemixtae strain R2C4 plasmid unnamed3, complete sequence	56818-56850	6	0.818
NZ_CP047585_1	1.5\|1253777\|33\|NZ_CP047585\|CRISPRCasFinder,CRT,PILER-CR	1253777-1253809	33	NZ_CP021653	Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence	1654104-1654136	6	0.818
NZ_CP047585_1	1.5\|1253777\|33\|NZ_CP047585\|CRISPRCasFinder,CRT,PILER-CR	1253777-1253809	33	NZ_CP021767	Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence	1654136-1654168	6	0.818
NZ_CP047585_1	1.5\|1253777\|33\|NZ_CP047585\|CRISPRCasFinder,CRT,PILER-CR	1253777-1253809	33	NZ_CP012688	Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence	1654102-1654134	6	0.818
NZ_CP047585_1	1.14\|1254329\|33\|NZ_CP047585\|CRISPRCasFinder,CRT,PILER-CR	1254329-1254361	33	NZ_CP018795	Campylobacter sp. RM12175 plasmid pVIC12175-2, complete sequence	3352-3384	7	0.788
NZ_CP047585_1	1.21\|1254755\|33\|NZ_CP047585\|CRISPRCasFinder,CRT,PILER-CR	1254755-1254787	33	KX620751	Propionibacterium phage Doucette, complete genome	19374-19406	7	0.788
NZ_CP047585_1	1.21\|1254755\|33\|NZ_CP047585\|CRISPRCasFinder,CRT,PILER-CR	1254755-1254787	33	NC_041894	Propionibacterium phage E6, complete genome	19380-19412	7	0.788
NZ_CP047585_1	1.13\|1254268\|33\|NZ_CP047585\|CRISPRCasFinder,CRT,PILER-CR	1254268-1254300	33	GU323708	Lactobacillus phage phiPYB5, complete genome	24948-24980	8	0.758
NZ_CP047585_1	1.28\|1255182\|33\|NZ_CP047585\|CRISPRCasFinder,CRT,PILER-CR	1255182-1255214	33	NZ_LR134459	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 17, complete sequence	22052-22084	8	0.758
NZ_CP047585_1	1.5\|1253777\|33\|NZ_CP047585\|CRISPRCasFinder,CRT,PILER-CR	1253777-1253809	33	JN848801	Vibrio phage VCY-phi, complete genome	4543-4575	9	0.727
NZ_CP047585_1	1.7\|1253899\|34\|NZ_CP047585\|CRISPRCasFinder,CRT,PILER-CR	1253899-1253932	34	NZ_CP054620	Azospirillum oryzae strain KACC 14407 plasmid unnamed5, complete sequence	360687-360720	9	0.735
NZ_CP047585_1	1.14\|1254329\|33\|NZ_CP047585\|CRISPRCasFinder,CRT,PILER-CR	1254329-1254361	33	NZ_CP051644	Staphylococcus caprae strain SY333 plasmid pSY333-92, complete sequence	52612-52644	9	0.727
NZ_CP047585_1	1.14\|1254329\|33\|NZ_CP047585\|CRISPRCasFinder,CRT,PILER-CR	1254329-1254361	33	AP013385	Uncultured Mediterranean phage uvMED DNA, complete genome, group G15, isolate: uvMED-CGR-C16-MedDCM-OCT-S39-C44	19599-19631	9	0.727
NZ_CP047585_1	1.19\|1254634\|32\|NZ_CP047585\|CRISPRCasFinder,CRT,PILER-CR	1254634-1254665	32	NZ_CP054621	Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence	881312-881343	9	0.719
NZ_CP047585_1	1.28\|1255182\|33\|NZ_CP047585\|CRISPRCasFinder,CRT,PILER-CR	1255182-1255214	33	NZ_LN832562	Paracoccus aminovorans isolate JCM7685 plasmid IV, complete sequence	694011-694043	9	0.727
NZ_CP047585_1	1.8\|1253961\|33\|NZ_CP047585\|CRISPRCasFinder,CRT,PILER-CR	1253961-1253993	33	MG592552	Vibrio phage 1.186.O._10N.286.49.E3, partial genome	13988-14020	10	0.697
NZ_CP047585_1	1.19\|1254634\|32\|NZ_CP047585\|CRISPRCasFinder,CRT,PILER-CR	1254634-1254665	32	CP033373	Lactobacillus fermentum strain DR9 plasmid unnamed2, complete sequence	16227-16258	10	0.688
NZ_CP047585_1	1.8\|1253961\|33\|NZ_CP047585\|CRISPRCasFinder,CRT,PILER-CR	1253961-1253993	33	MG592393	Vibrio phage 1.007.O._10N.261.55.F9, partial genome	16057-16089	11	0.667

1. spacer 1.8|1253961|33|NZ_CP047585|CRISPRCasFinder,CRT,PILER-CR matches to MN830252 (Lactobacillus phage JNU_P1, complete genome) position: , mismatch: 0, identity: 1.0

ccattagatggattcaagcgcggcgatgatcag	CRISPR spacer
ccattagatggattcaagcgcggcgatgatcag	Protospacer
*********************************

2. spacer 1.8|1253961|33|NZ_CP047585|CRISPRCasFinder,CRT,PILER-CR matches to HQ141410 (Lactobacillus phage LF1, complete genome) position: , mismatch: 0, identity: 1.0

ccattagatggattcaagcgcggcgatgatcag	CRISPR spacer
ccattagatggattcaagcgcggcgatgatcag	Protospacer
*********************************

3. spacer 1.9|1254022|33|NZ_CP047585|CRISPRCasFinder,CRT,PILER-CR matches to MN830252 (Lactobacillus phage JNU_P1, complete genome) position: , mismatch: 0, identity: 1.0

ccgattagacgattctgttttagtcggcttgaa	CRISPR spacer
ccgattagacgattctgttttagtcggcttgaa	Protospacer
*********************************

4. spacer 1.9|1254022|33|NZ_CP047585|CRISPRCasFinder,CRT,PILER-CR matches to HQ141410 (Lactobacillus phage LF1, complete genome) position: , mismatch: 0, identity: 1.0

ccgattagacgattctgttttagtcggcttgaa	CRISPR spacer
ccgattagacgattctgttttagtcggcttgaa	Protospacer
*********************************

5. spacer 1.24|1254938|33|NZ_CP047585|CRISPRCasFinder,CRT,PILER-CR matches to MN830252 (Lactobacillus phage JNU_P1, complete genome) position: , mismatch: 0, identity: 1.0

acgccaacgattgaccagacaaccggccactgg	CRISPR spacer
acgccaacgattgaccagacaaccggccactgg	Protospacer
*********************************

6. spacer 1.22|1254816|33|NZ_CP047585|CRISPRCasFinder,CRT,PILER-CR matches to NC_029068 (Lactobacillus phage LfeSau, complete genome) position: , mismatch: 1, identity: 0.97

ttagtgggaaggcgttcattccggacgcggcaa	CRISPR spacer
ttagtgggaaggcgttcattccggacgcggcga	Protospacer
*******************************.*

7. spacer 1.11|1254144|35|NZ_CP047585|CRISPRCasFinder,CRT,PILER-CR matches to GU323708 (Lactobacillus phage phiPYB5, complete genome) position: , mismatch: 2, identity: 0.943

cccggtcacccggccataattctactgtctccacg	CRISPR spacer
cccggtcgcccggccataattctattgtctccacg	Protospacer
*******.****************.**********

8. spacer 1.19|1254634|32|NZ_CP047585|CRISPRCasFinder,CRT,PILER-CR matches to NC_029068 (Lactobacillus phage LfeSau, complete genome) position: , mismatch: 2, identity: 0.938

cacctaggcccaggcccccgacgtccattaca	CRISPR spacer
cacctagacccaggctcccgacgtccattaca	Protospacer
*******.*******.****************

9. spacer 1.20|1254694|33|NZ_CP047585|CRISPRCasFinder,CRT,PILER-CR matches to NC_029068 (Lactobacillus phage LfeSau, complete genome) position: , mismatch: 2, identity: 0.939

tagcaacgaacccactggttaggggtcgctttg	CRISPR spacer
tagcaacgagtccactggttaggggtcgctttg	Protospacer
*********..**********************

10. spacer 1.27|1255121|33|NZ_CP047585|CRISPRCasFinder,CRT,PILER-CR matches to GU323708 (Lactobacillus phage phiPYB5, complete genome) position: , mismatch: 2, identity: 0.939

cagctcggttagagtccttagctgtatggctga	CRISPR spacer
cagctctgttagaatccttagctgtatggctga	Protospacer
****** ******.*******************

11. spacer 1.28|1255182|33|NZ_CP047585|CRISPRCasFinder,CRT,PILER-CR matches to NC_029068 (Lactobacillus phage LfeSau, complete genome) position: , mismatch: 2, identity: 0.939

tttcaccgacgattcggaaggcgcggccggtgg	CRISPR spacer
tttcaccgacgattcggaagacgcggtcggtgg	Protospacer
********************.*****.******

12. spacer 1.14|1254329|33|NZ_CP047585|CRISPRCasFinder,CRT,PILER-CR matches to HQ141410 (Lactobacillus phage LF1, complete genome) position: , mismatch: 3, identity: 0.909

cacttttgtatttctgcttcttgtcgctagccg	CRISPR spacer
cacttttgtatttatgcttcttatcgctagcca	Protospacer
************* ********.*********.

13. spacer 1.21|1254755|33|NZ_CP047585|CRISPRCasFinder,CRT,PILER-CR matches to NC_029068 (Lactobacillus phage LfeSau, complete genome) position: , mismatch: 3, identity: 0.909

tacacttcgggttcacatagccagtcccttgcg	CRISPR spacer
tacacttcgggttaacataaccagtcccttgtg	Protospacer
************* *****.***********.*

14. spacer 1.26|1255060|33|NZ_CP047585|CRISPRCasFinder,CRT,PILER-CR matches to NC_029068 (Lactobacillus phage LfeSau, complete genome) position: , mismatch: 3, identity: 0.909

caggctggaaagcccgtgctaagctgtcgtaga	CRISPR spacer
ccggctggaaagccctcgctaagctgtcgtaga	Protospacer
* ************* .****************

15. spacer 1.17|1254512|33|NZ_CP047585|CRISPRCasFinder,CRT,PILER-CR matches to MN830253 (Lactobacillus phage JNU_P5, complete genome) position: , mismatch: 4, identity: 0.879

ccggttgccggatgcccaacgtgttctacttgg	CRISPR spacer
ccggttgccggatgtccaacatgttctactggt	Protospacer
**************.*****.********* *

16. spacer 1.1|1253534|33|NZ_CP047585|CRISPRCasFinder matches to NZ_CP041164 (Leisingera aquaemixtae strain R2C4 plasmid unnamed3, complete sequence) position: , mismatch: 6, identity: 0.818

-cgaggcacacggagacagggatcccggcaagca	CRISPR spacer
acgtgg-gcccggagacagagatcccggccagca	Protospacer
 ** ** .* *********.********* ****

17. spacer 1.5|1253777|33|NZ_CP047585|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021653 (Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.818

aatggaggcaaaaaatgaaggaaatcaacgata-	CRISPR spacer
tttggaggcaaaaaataaaggatatcaa-gatgt	Protospacer
  **************.***** ***** ***.

18. spacer 1.5|1253777|33|NZ_CP047585|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021767 (Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.818

aatggaggcaaaaaatgaaggaaatcaacgata-	CRISPR spacer
tttggaggcaaaaaataaaggatatcaa-gatgt	Protospacer
  **************.***** ***** ***.

19. spacer 1.5|1253777|33|NZ_CP047585|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012688 (Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.818

aatggaggcaaaaaatgaaggaaatcaacgata-	CRISPR spacer
tttggaggcaaaaaataaaggatatcaa-gatgt	Protospacer
  **************.***** ***** ***.

20. spacer 1.14|1254329|33|NZ_CP047585|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP018795 (Campylobacter sp. RM12175 plasmid pVIC12175-2, complete sequence) position: , mismatch: 7, identity: 0.788

cacttttgtatttctgcttcttgtcgctagccg	CRISPR spacer
aatttttctatttctgcttcgtgtcgcttgatg	Protospacer
 *.**** ************ ******* * .*

21. spacer 1.21|1254755|33|NZ_CP047585|CRISPRCasFinder,CRT,PILER-CR matches to KX620751 (Propionibacterium phage Doucette, complete genome) position: , mismatch: 7, identity: 0.788

tacacttcgggttcacatagccagtcccttgcg	CRISPR spacer
cacggttcgggttcacatagccggtgccttcgg	Protospacer
.**. *****************.** ****  *

22. spacer 1.21|1254755|33|NZ_CP047585|CRISPRCasFinder,CRT,PILER-CR matches to NC_041894 (Propionibacterium phage E6, complete genome) position: , mismatch: 7, identity: 0.788

tacacttcgggttcacatagccagtcccttgcg	CRISPR spacer
cacggttcgggttcacatagccggtgccttcgg	Protospacer
.**. *****************.** ****  *

23. spacer 1.13|1254268|33|NZ_CP047585|CRISPRCasFinder,CRT,PILER-CR matches to GU323708 (Lactobacillus phage phiPYB5, complete genome) position: , mismatch: 8, identity: 0.758

gattagtatcgccggtcataatggccggcttta	CRISPR spacer
ataaaaaagcgccggtcataatggccggcctta	Protospacer
.   *. * ********************.***

24. spacer 1.28|1255182|33|NZ_CP047585|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LR134459 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 17, complete sequence) position: , mismatch: 8, identity: 0.758

---tttcaccgacgattcggaaggcgcggccggtgg	CRISPR spacer
gggtctggccgatg---cggaaggcgcggtcggtgg	Protospacer
   *.* .****.*   ************.******

25. spacer 1.5|1253777|33|NZ_CP047585|CRISPRCasFinder,CRT,PILER-CR matches to JN848801 (Vibrio phage VCY-phi, complete genome) position: , mismatch: 9, identity: 0.727

aatggaggcaaaaaatgaaggaaatcaacgata	CRISPR spacer
tcaggaggcaaataaggaaggaaatcagacaaa	Protospacer
   ********* ** ***********.  * *

26. spacer 1.7|1253899|34|NZ_CP047585|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP054620 (Azospirillum oryzae strain KACC 14407 plasmid unnamed5, complete sequence) position: , mismatch: 9, identity: 0.735

ttacctct-tcggtctcggtagtaatgcccatcaa	CRISPR spacer
-cgcggctggcggtctcggtggtaatgcccagcac	Protospacer
 ..*  **  **********.********** **

27. spacer 1.14|1254329|33|NZ_CP047585|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP051644 (Staphylococcus caprae strain SY333 plasmid pSY333-92, complete sequence) position: , mismatch: 9, identity: 0.727

cacttttgtatttctgcttcttgtcgctagccg	CRISPR spacer
gctttttgtctttctgcttcttgttgcttttct	Protospacer
  .****** **************.***  .*

28. spacer 1.14|1254329|33|NZ_CP047585|CRISPRCasFinder,CRT,PILER-CR matches to AP013385 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G15, isolate: uvMED-CGR-C16-MedDCM-OCT-S39-C44) position: , mismatch: 9, identity: 0.727

cacttttgtatttctgcttcttgtcgctagccg	CRISPR spacer
cttctaaatatttttgcttcttgtcgctatcct	Protospacer
* ..*  .*****.*************** **

29. spacer 1.19|1254634|32|NZ_CP047585|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP054621 (Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence) position: , mismatch: 9, identity: 0.719

cacctaggcccaggcccccgacgtccattaca	CRISPR spacer
catgccggccctggcccccgacgtcgattggg	Protospacer
**. . ***** ************* ***. .

30. spacer 1.28|1255182|33|NZ_CP047585|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LN832562 (Paracoccus aminovorans isolate JCM7685 plasmid IV, complete sequence) position: , mismatch: 9, identity: 0.727

tttcaccgacgattcggaaggcgcggccggtgg	CRISPR spacer
ctgggccgacggttcggaaggcgcggtcgatct	Protospacer
.*  .******.**************.**.*

31. spacer 1.8|1253961|33|NZ_CP047585|CRISPRCasFinder,CRT,PILER-CR matches to MG592552 (Vibrio phage 1.186.O._10N.286.49.E3, partial genome) position: , mismatch: 10, identity: 0.697

ccattagatggattcaagcgcggcgatgatcag	CRISPR spacer
gtggaggatggattcaagcgctacgatgatgcg	Protospacer
 ..  .*************** .*******  *

32. spacer 1.19|1254634|32|NZ_CP047585|CRISPRCasFinder,CRT,PILER-CR matches to CP033373 (Lactobacillus fermentum strain DR9 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.688

cacctaggcccaggcccccgacgtccattaca	CRISPR spacer
tcataaagcccagccccccgacttccattagg	Protospacer
.  . *.****** ******** ******* .

33. spacer 1.8|1253961|33|NZ_CP047585|CRISPRCasFinder,CRT,PILER-CR matches to MG592393 (Vibrio phage 1.007.O._10N.261.55.F9, partial genome) position: , mismatch: 11, identity: 0.667

ccattagatggattcaagcgcggcgatgatcag	CRISPR spacer
gtggaggatggattcaagcgctacgatgatgct	Protospacer
 ..  .*************** .*******

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

16149 : 93723

Staphylococcus_phage(18.18%)

protease,transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085013424.1\|16149_17148_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	1.3e-50	38.4
WP_003685635.1\|18928_19636_+	response regulator transcription factor	W8CYM9	Bacillus_phage	7.9e-42	39.8
WP_049184174.1\|19647_21507_+	cell wall metabolism sensor histidine kinase WalK	W8CYF6	Bacillus_phage	2.9e-35	35.6
WP_062813557.1\|21490_22789_+	hypothetical protein	NA	NA	NA	NA
WP_062813556.1\|22790_23591_+	hypothetical protein	NA	NA	NA	NA
WP_080983508.1\|23605_24421_+	MBL fold metallo-hydrolase	A0A2H4J3R0	uncultured_Caudovirales_phage	1.6e-33	32.7
WP_049184179.1\|24495_25767_+	PDZ domain-containing protein	A0A1B1IT49	uncultured_Mediterranean_phage	3.4e-19	29.3
WP_021350198.1\|26274_26754_+	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	NA	NA	NA	NA
WP_003685648.1\|26968_27394_+	Rrf2 family transcriptional regulator	NA	NA	NA	NA
WP_049184183.1\|27399_28338_+	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_062813555.1\|28808_30152_+	SLC45 family MFS transporter	NA	NA	NA	NA
WP_062813554.1\|30164_32411_+	glycoside hydrolase family 65 protein	NA	NA	NA	NA
WP_163601257.1\|32557_33226_+	beta-phosphoglucomutase	NA	NA	NA	NA
WP_076810820.1\|33308_34472_-	ABC transporter permease	NA	NA	NA	NA
WP_062813552.1\|34533_35436_-	ATP-binding cassette domain-containing protein	A0A285PWH2	Cedratvirus	1.3e-17	25.4
WP_062813551.1\|35687_36665_-	choloylglycine hydrolase family protein	A7IWP6	Paramecium_bursaria_Chlorella_virus	3.6e-21	30.2
WP_057194181.1\|36719_37655_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_049182901.1\|37954_38947_-	D-2-hydroxyacid dehydrogenase	M1HTA3	Paramecium_bursaria_Chlorella_virus	8.7e-39	32.2
WP_049182899.1\|38962_40147_-	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_003685663.1\|40495_40726_+	hypothetical protein	NA	NA	NA	NA
WP_049182894.1\|40810_42904_+\|protease	ATP-dependent Clp protease ATP-binding subunit	H6X3M6	Enterobacteria_phage	1.9e-120	40.1
WP_049182522.1\|43199_44660_+	cardiolipin synthase	NA	NA	NA	NA
WP_049182524.1\|45143_48878_+	ATP-dependent helicase	NA	NA	NA	NA
WP_163601258.1\|48884_52898_+	helicase-exonuclease AddAB subunit AddA	A7KV33	Bacillus_phage	3.3e-12	21.4
WP_049182527.1\|52897_53761_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	7.3e-58	46.4
WP_076810810.1\|53998_55624_+	glycerophosphodiester phosphodiesterase	NA	NA	NA	NA
WP_048339891.1\|55917_56274_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	7.0e-15	39.1
WP_062813546.1\|56312_57428_-	ABC transporter permease	NA	NA	NA	NA
WP_049182572.1\|57420_58152_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	3.7e-26	33.2
WP_049182571.1\|58289_58844_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_003682354.1\|58924_59899_-	GMP reductase	Q4ZCY7	Staphylococcus_virus	4.9e-135	69.0
WP_163601259.1\|60097_61387_+	adenylosuccinate synthase	A0A160ER07	Powai_lake_megavirus	3.2e-73	37.6
WP_049182569.1\|61713_63096_+	NAD-dependent succinate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_003685686.1\|63377_63917_+	bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase PyrR	NA	NA	NA	NA
WP_049182567.1\|64035_64767_+	orotidine-5'-phosphate decarboxylase	NA	NA	NA	NA
WP_163601260.1\|64766_65393_+	orotate phosphoribosyltransferase	S4VS55	Pandoravirus	4.8e-35	38.6
WP_048339895.1\|65492_65822_+	hypothetical protein	NA	NA	NA	NA
WP_021350374.1\|66292_66685_-	hypothetical protein	NA	NA	NA	NA
WP_015638436.1\|66827_68366_+	glycosyltransferase	NA	NA	NA	NA
WP_163601261.1\|68365_69862_+	accessory Sec system glycosyltransferase Asp1	NA	NA	NA	NA
WP_003682375.1\|70271_71114_+	MetQ/NlpA family ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_015638439.1\|71139_72204_+	methionine ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.5e-28	35.8
WP_049182934.1\|72196_72898_+	ABC transporter permease	NA	NA	NA	NA
WP_163601775.1\|73023_74172_+	ArgE/DapE family deacylase	NA	NA	NA	NA
WP_163601262.1\|74355_75780_-	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	A0A2K5B251	Erysipelothrix_phage	3.3e-71	33.9
WP_163601263.1\|76944_77970_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	7.1e-44	36.0
WP_062813540.1\|78028_79408_-	aspartate ammonia-lyase	NA	NA	NA	NA
WP_163601264.1\|79767_79980_+	diguanylate cyclase	NA	NA	NA	NA
WP_057194201.1\|80163_80748_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_057194202.1\|82664_83840_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_057194203.1\|84099_84333_-	hypothetical protein	NA	NA	NA	NA
WP_163601265.1\|84415_85636_+\|transposase	IS256 family transposase	A0A0K2CZ57	Paenibacillus_phage	1.4e-94	46.2
WP_057195068.1\|86403_87804_+	amino acid permease	NA	NA	NA	NA
WP_062813536.1\|87953_89282_+	D-serine ammonia-lyase	NA	NA	NA	NA
WP_163601266.1\|89521_90742_+\|transposase	IS256 family transposase	A0A0K2CZ57	Paenibacillus_phage	5.3e-94	46.0
WP_163601267.1\|91801_92746_+	aldo/keto reductase	A0A1V0SKP9	Klosneuvirus	4.6e-05	35.8
WP_163601268.1\|92760_93723_-\|transposase	IS30 family transposase	NA	NA	NA	NA

DBSCAN-SWA_2

98649 : 161368

Streptococcus_phage(19.05%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_076811120.1\|98649_99102_-\|transposase	IS200/IS605 family transposase	A0A0P0IQC6	Lactobacillus_phage	2.8e-32	51.5
WP_163601270.1\|99180_100431_+\|transposase	transposase	A0A286QQE5	Streptococcus_phage	2.6e-56	37.0
WP_070955325.1\|100643_101777_+	exonuclease SbcCD subunit D	R4JGS2	Bacillus_phage	3.1e-08	25.0
WP_163601271.1\|101773_104878_+	SMC family ATPase	NA	NA	NA	NA
WP_049182845.1\|105165_106464_+\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	4.7e-93	49.8
WP_163601272.1\|106966_107980_-\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_163601273.1\|108237_109491_-\|tRNA	tyrosine--tRNA ligase	A0A1L2CUL7	Pectobacterium_phage	3.9e-84	41.7
WP_049184295.1\|109960_111415_+	ABC transporter substrate-binding protein/permease	NA	NA	NA	NA
WP_049184293.1\|111418_112162_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.6e-32	41.9
WP_111522950.1\|112621_113995_+	amino acid permease	NA	NA	NA	NA
WP_163601274.1\|114318_115569_-\|transposase	transposase	A0A286QQE5	Streptococcus_phage	1.8e-57	36.3
WP_012390701.1\|115647_116100_+\|transposase	IS200/IS605 family transposase	A0A0P0IQC6	Lactobacillus_phage	2.8e-32	51.5
WP_163601275.1\|116484_117672_+\|transposase	IS256 family transposase	NA	NA	NA	NA
WP_015638455.1\|118137_119337_+	nucleoside transporter	NA	NA	NA	NA
WP_163601276.1\|119572_120493_+	ribonucleoside hydrolase RihC	NA	NA	NA	NA
WP_163601776.1\|120681_121419_+	16S rRNA (guanine(527)-N(7))-methyltransferase RsmG	NA	NA	NA	NA
WP_023465732.1\|121437_122373_+	nucleoid occlusion protein	S5VSZ7	Leptospira_phage	2.7e-13	32.1
WP_163601277.1\|122386_123220_+	ParB/RepB/Spo0J family partition protein	I3NLC2	Bifidobacterium_phage	1.8e-16	32.9
WP_003682416.1\|123232_123433_+	DUF951 domain-containing protein	NA	NA	NA	NA
WP_003685747.1\|123448_124546_+	redox-regulated ATPase YchF	NA	NA	NA	NA
WP_054173577.1\|124579_125353_+	DUF1129 domain-containing protein	NA	NA	NA	NA
WP_163601278.1\|125625_126768_+	guanosine monophosphate reductase	A0A1V0SHK8	Klosneuvirus	5.1e-59	32.6
WP_163601279.1\|127117_128131_+	LytR family transcriptional regulator	NA	NA	NA	NA
WP_163601280.1\|128130_128901_+	exopolysaccharide biosynthesis protein	NA	NA	NA	NA
WP_163601281.1\|128917_129658_+	CpsD/CapB family tyrosine-protein kinase	NA	NA	NA	NA
WP_163601282.1\|129684_130455_+	exopolysaccharide biosynthesis protein	NA	NA	NA	NA
WP_163601283.1\|130442_131111_+	sugar transferase	NA	NA	NA	NA
WP_163601268.1\|132095_133058_-\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_163601284.1\|133621_134413_+	DUF4422 domain-containing protein	NA	NA	NA	NA
WP_163601285.1\|134409_135309_+	capsular polysaccharide synthesis family protein	NA	NA	NA	NA
WP_163601286.1\|135333_136320_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_163601287.1\|136343_137534_+	hypothetical protein	NA	NA	NA	NA
WP_163601288.1\|137656_138151_+	serine acetyltransferase	NA	NA	NA	NA
WP_163601289.1\|138150_139590_+	hypothetical protein	NA	NA	NA	NA
WP_163601777.1\|139640_140759_+	UDP-galactopyranose mutase	E4ZFQ1	Streptococcus_phage	2.0e-172	78.1
WP_163601290.1\|140807_141617_+	beta-1,6-N-acetylglucosaminyltransferase	NA	NA	NA	NA
WP_080965022.1\|141862_142297_+\|transposase	transposase	A0A0C5AJ29	Paenibacillus_phage	3.7e-10	28.9
WP_163601291.1\|143490_143997_-	cupin domain-containing protein	A0A291ATU0	Pandoravirus	7.4e-10	34.1
WP_031284839.1\|144193_144883_+	response regulator transcription factor	W8CYM9	Bacillus_phage	1.8e-35	36.6
WP_163601292.1\|145080_146223_+	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	2.5e-29	29.5
WP_163601293.1\|146222_147518_+	D-alanyl-D-alanine carboxypeptidase	NA	NA	NA	NA
WP_163601294.1\|147860_148736_+	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_057728087.1\|148735_149155_+	AzlD domain-containing protein	NA	NA	NA	NA
WP_076811459.1\|149267_149528_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_076811457.1\|149527_149875_+	type II toxin-antitoxin system PemK/MazF family toxin	NA	NA	NA	NA
WP_062813508.1\|149888_150434_+	esterase	NA	NA	NA	NA
WP_163601295.1\|150667_151855_-	class I SAM-dependent methyltransferase	A0A2I2L5L3	Orpheovirus	4.0e-46	33.0
WP_163601296.1\|151988_152177_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_163601297.1\|152331_153372_+	AI-2E family transporter	NA	NA	NA	NA
WP_163601298.1\|153459_155121_+	formate--tetrahydrofolate ligase	NA	NA	NA	NA
WP_163601299.1\|155402_155888_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	1.1e-21	44.8
WP_035424032.1\|155871_157011_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_163601300.1\|157029_158325_+	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	6.3e-21	32.7
WP_014081459.1\|159794_160193_+\|transposase	IS200/IS605 family transposase	A0A286QN76	Streptococcus_phage	1.1e-45	62.9
WP_062813495.1\|160192_161368_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A0P0ICY9	Lactobacillus_phage	1.1e-112	54.4

DBSCAN-SWA_3

183738 : 207927

Lactobacillus_phage(44.44%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014081459.1\|183738_184137_+\|transposase	IS200/IS605 family transposase	A0A286QN76	Streptococcus_phage	1.1e-45	62.9
WP_062813495.1\|184136_185312_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A0P0ICY9	Lactobacillus_phage	1.1e-112	54.4
WP_163601312.1\|185463_185982_+	multidrug efflux MFS transporter	NA	NA	NA	NA
WP_062813497.1\|186029_186506_-	nucleoside 2-deoxyribosyltransferase	A0A2P0ZL88	Lactobacillus_phage	4.5e-17	35.9
WP_163601313.1\|192222_193146_+\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	1.1e-32	32.4
WP_163601314.1\|193448_194084_-	DUF4767 domain-containing protein	NA	NA	NA	NA
WP_014081459.1\|194206_194605_+\|transposase	IS200/IS605 family transposase	A0A286QN76	Streptococcus_phage	1.1e-45	62.9
WP_062813495.1\|194604_195780_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A0P0ICY9	Lactobacillus_phage	1.1e-112	54.4
WP_062813494.1\|196061_196451_+	tautomerase family protein	NA	NA	NA	NA
WP_079247428.1\|196445_196580_-	winged helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_049182491.1\|196582_197101_-	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_062813492.1\|197185_197842_+	nitroreductase	NA	NA	NA	NA
WP_062813491.1\|198688_199249_+	hypothetical protein	NA	NA	NA	NA
WP_062813490.1\|200040_200925_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_062813489.1\|201037_201547_+	hypothetical protein	NA	NA	NA	NA
WP_062813488.1\|201533_201890_+	hypothetical protein	NA	NA	NA	NA
WP_163601315.1\|201901_202645_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_062813486.1\|202730_203552_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	9.5e-39	36.1
WP_062813485.1\|203614_203809_+	CsbD family protein	NA	NA	NA	NA
WP_163601316.1\|204303_204672_+	DUF2255 family protein	NA	NA	NA	NA
WP_062813483.1\|205463_206048_+	hypothetical protein	NA	NA	NA	NA
WP_012390701.1\|206145_206598_-\|transposase	IS200/IS605 family transposase	A0A0P0IQC6	Lactobacillus_phage	2.8e-32	51.5
WP_163601317.1\|206676_207927_+\|transposase	transposase	A0A286QQE5	Streptococcus_phage	1.9e-54	36.2

DBSCAN-SWA_4

225340 : 233660

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012390781.1\|225340_225988_+	nitroreductase	M1I6Q5	Acanthocystis_turfacea_Chlorella_virus	1.8e-16	27.1
WP_003683956.1\|225997_226729_+	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_003683957.1\|226739_227054_+	DNA-binding protein	A0A2R3ZXQ3	Staphylococcus_phage	6.6e-17	40.4
WP_049183165.1\|227178_228219_+	Zn-dependent alcohol dehydrogenase	E3SJ82	Synechococcus_phage	2.4e-10	26.3
WP_049183163.1\|228426_230952_-	M1 family metallopeptidase	A0A0P0IY26	Acinetobacter_phage	9.3e-69	26.4
WP_049183161.1\|231126_231687_-	hypothetical protein	NA	NA	NA	NA
WP_049183159.1\|231925_232783_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	1.6e-49	36.9
WP_163601321.1\|232796_233660_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	1.7e-51	40.8

DBSCAN-SWA_5

358811 : 367283

Enterococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_076810904.1\|358811_360983_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	3.0e-249	59.4
WP_004563324.1\|361082_361304_-	glutaredoxin-like protein NrdH	X2KRY7	Enterococcus_phage	3.2e-10	54.7
WP_049184662.1\|361590_362085_+	nucleoside deaminase	A0A2H4PQS8	Staphylococcus_phage	7.5e-07	34.4
WP_062813443.1\|362340_364032_+	DNA polymerase III subunit gamma/tau	A0A1U9WR94	Streptococcus_virus	3.9e-55	38.6
WP_004562761.1\|364054_364363_+	YbaB/EbfC family nucleoid-associated protein	NA	NA	NA	NA
WP_049184668.1\|364378_364978_+	recombination protein RecR	NA	NA	NA	NA
WP_004562763.1\|364979_365228_+	YaaL family protein	NA	NA	NA	NA
WP_062813442.1\|365247_365892_+	dTMP kinase	M1PSC7	Streptococcus_phage	2.8e-54	53.1
WP_004562765.1\|365904_366225_+	hypothetical protein	NA	NA	NA	NA
WP_163601346.1\|366242_367283_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	2.1e-27	32.3

DBSCAN-SWA_6

443896 : 494309

Streptococcus_phage(22.22%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_163601354.1\|443896_445141_-\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	2.1e-45	31.6
WP_004563273.1\|445645_446128_+	tryptophan-rich sensory protein	NA	NA	NA	NA
WP_163601355.1\|447348_448488_+\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	1.4e-43	33.6
WP_135292835.1\|448671_449835_+	hypothetical protein	NA	NA	NA	NA
WP_012390875.1\|450768_451782_+	type I glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_163601356.1\|451864_453070_+	phosphoglycerate kinase	NA	NA	NA	NA
WP_163601357.1\|453174_453909_+	triose-phosphate isomerase	NA	NA	NA	NA
WP_135293564.1\|453951_454726_+\|transposase	IS5 family transposase	A0A0N9SJT9	Paenibacillus_phage	4.8e-16	36.4
WP_163601358.1\|454916_456239_+	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	2.6e-171	70.1
WP_163601359.1\|456432_457827_+	amino acid permease	NA	NA	NA	NA
WP_099032354.1\|457916_459467_+	ClC family H(+)/Cl(-) exchange transporter	NA	NA	NA	NA
WP_003682647.1\|459544_459769_+	preprotein translocase subunit SecG	NA	NA	NA	NA
WP_163601360.1\|459821_462215_+	ribonuclease R	Q0GXV6	Lactococcus_phage	1.5e-89	39.0
WP_057194886.1\|462235_462709_+	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	2.6e-41	56.1
WP_057727744.1\|462736_463321_-	hypothetical protein	NA	NA	NA	NA
WP_057194884.1\|463458_464148_+	uracil-DNA glycosylase	A0A0B5IW78	Pandoravirus	1.1e-45	45.1
WP_003682658.1\|464181_465156_+	phosphate acetyltransferase	NA	NA	NA	NA
WP_003682659.1\|465164_465617_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	NA	NA	NA	NA
WP_163601361.1\|465616_466132_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_004563262.1\|466261_466801_-	exonuclease	A0A1S5SFA9	Streptococcus_phage	4.8e-23	37.4
WP_003682662.1\|466928_467825_+	UDP-N-acetylmuramate dehydrogenase	NA	NA	NA	NA
WP_086439729.1\|467839_468682_+	TIGR00159 family protein	NA	NA	NA	NA
WP_057194881.1\|468671_469550_+	hypothetical protein	NA	NA	NA	NA
WP_003682665.1\|469589_470948_+	phosphoglucosamine mutase	A0A127AWJ1	Bacillus_phage	3.6e-19	26.9
WP_163601362.1\|471161_472982_+	glutamine--fructose-6-phosphate transaminase (isomerizing)	M1HVL7	Paramecium_bursaria_Chlorella_virus	9.9e-89	35.2
WP_004563258.1\|473262_473574_+	hypothetical protein	NA	NA	NA	NA
WP_163601363.1\|473583_475434_+	acetyltransferase	NA	NA	NA	NA
WP_163601364.1\|475464_476283_+	HAD family phosphatase	NA	NA	NA	NA
WP_057727752.1\|476603_477185_+	LysM peptidoglycan-binding domain-containing protein	A0A249XZV3	Enterococcus_phage	3.4e-27	51.6
WP_163601365.1\|477554_478478_-\|transposase	IS30 family transposase	H7BVY4	unidentified_phage	2.5e-32	31.6
WP_057194878.1\|478639_479668_-	putative sulfate exporter family transporter	NA	NA	NA	NA
WP_062813400.1\|479788_480694_+	LysR family transcriptional regulator	A0A2H4J8I9	uncultured_Caudovirales_phage	7.5e-05	41.2
WP_076811363.1\|480790_481753_-	mannose-6-phosphate isomerase, class I	NA	NA	NA	NA
WP_163601366.1\|481839_482679_-	DegV family protein	A0A1X9I5J4	Streptococcus_phage	1.1e-47	39.8
WP_079247423.1\|482842_483358_+	DUF1836 domain-containing protein	NA	NA	NA	NA
WP_163601367.1\|483589_484531_-	Dyp-type peroxidase	A0A0B5JDC7	Pandoravirus	2.0e-08	30.4
WP_062813396.1\|485005_485989_+	PTS mannose transporter subunit IIAB	NA	NA	NA	NA
WP_057194873.1\|486008_486812_+	PTS mannose/fructose/sorbose transporter subunit IIC	NA	NA	NA	NA
WP_057728115.1\|486840_487761_+	PTS mannose/fructose/sorbose transporter family subunit IID	NA	NA	NA	NA
WP_163601368.1\|487762_488113_+	DUF956 family protein	NA	NA	NA	NA
WP_163601369.1\|488660_489593_-\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	4.8e-39	36.8
WP_057728161.1\|489778_490501_+	response regulator transcription factor	NA	NA	NA	NA
WP_057728160.1\|490500_492003_+	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	1.2e-34	34.2
WP_057194868.1\|492205_493066_+	sugar transporter	NA	NA	NA	NA
WP_163601780.1\|493400_494309_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	8.9e-14	26.9

DBSCAN-SWA_7

693231 : 793142

112

Lactobacillus_phage(45.1%)

portal,head,protease,integrase,terminase,tail,capsid,tRNA,transposase

attL 710550:710574|attR 781792:781816

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_049182889.1\|693231_694482_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	4.8e-135	56.9
WP_049182890.1\|694495_695089_+	YihA family ribosome biogenesis GTP-binding protein	NA	NA	NA	NA
WP_003682052.1\|695088_695388_+	nucleoside triphosphate pyrophosphohydrolase family protein	A0A1S7FYY8	Listeria_phage	6.9e-24	51.5
WP_163601403.1\|695654_695801_-	hypothetical protein	NA	NA	NA	NA
WP_049183701.1\|695988_696735_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.6e-29	37.3
WP_057728004.1\|697061_698873_+	excinuclease ABC subunit UvrC	NA	NA	NA	NA
WP_049183705.1\|698937_700245_+	GTPase ObgE	NA	NA	NA	NA
WP_062813279.1\|700271_701204_+	ribonuclease Z	NA	NA	NA	NA
WP_062813278.1\|701224_702064_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_163601404.1\|702136_704434_+	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	6.5e-69	29.5
WP_049183714.1\|704447_704975_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	2.3e-30	44.0
WP_163601405.1\|705342_705696_+	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_003682040.1\|705775_706774_-	D-2-hydroxyacid dehydrogenase	M1HTA3	Paramecium_bursaria_Chlorella_virus	1.8e-47	34.0
WP_057728092.1\|707275_708085_+	2-keto-4-pentenoate hydratase	NA	NA	NA	NA
WP_057728091.1\|708247_708784_+	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_049183717.1\|708794_709076_+	hypothetical protein	NA	NA	NA	NA
WP_049183719.1\|709075_709405_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_053093318.1\|709751_710060_-	hypothetical protein	NA	NA	NA	NA
710550:710574	attL	NA	NA	NA	NA
WP_163601406.1\|710703_712293_-	asparagine synthase B	A0A0G2Y369	Acanthamoeba_polyphaga_mimivirus	2.8e-103	39.7
WP_163601407.1\|713161_714106_+	3-hydroxyacyl-CoA dehydrogenase family protein	NA	NA	NA	NA
WP_049183730.1\|714187_714628_-	hypothetical protein	NA	NA	NA	NA
WP_163601408.1\|714638_715628_-	LacI family transcriptional regulator	NA	NA	NA	NA
WP_057728090.1\|715649_716096_-	nucleoside 2-deoxyribosyltransferase	A0A1D3SPR3	Enterococcus_phage	1.8e-20	36.7
WP_163601409.1\|716196_716817_+	DUF308 domain-containing protein	NA	NA	NA	NA
WP_163601410.1\|717061_718147_-\|integrase	tyrosine-type recombinase/integrase	A0A0M9JJ77	Lactobacillus_phage	5.7e-108	54.9
WP_163601411.1\|718175_718397_-	hypothetical protein	NA	NA	NA	NA
WP_046948017.1\|718747_719608_-	hypothetical protein	NA	NA	NA	NA
WP_046948018.1\|719673_720018_-	DUF1049 domain-containing protein	NA	NA	NA	NA
WP_163601781.1\|720157_720637_-	hypothetical protein	E9LUL0	Lactobacillus_phage	1.0e-45	65.5
WP_085013424.1\|720661_721660_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	1.3e-50	38.4
WP_157787456.1\|721904_722078_+	hypothetical protein	NA	NA	NA	NA
WP_163601412.1\|722052_723057_-	hypothetical protein	NA	NA	NA	NA
WP_163601413.1\|723090_723618_-	hypothetical protein	NA	NA	NA	NA
WP_163601414.1\|723639_724083_-	hypothetical protein	NA	NA	NA	NA
WP_163601415.1\|724109_724334_+	hypothetical protein	NA	NA	NA	NA
WP_163601416.1\|724305_724605_-	hypothetical protein	NA	NA	NA	NA
WP_163601417.1\|724866_725259_-	ImmA/IrrE family metallo-endopeptidase	E9LUL3	Lactobacillus_phage	5.1e-67	95.4
WP_163601418.1\|725262_725586_-	helix-turn-helix transcriptional regulator	E9LUL4	Lactobacillus_phage	1.5e-40	77.6
WP_163601419.1\|725741_725957_+	helix-turn-helix transcriptional regulator	E9LUL5	Lactobacillus_phage	1.6e-14	54.9
WP_163601420.1\|725989_726778_+	phage antirepressor	A0A0A7DN31	Lactobacillus_phage	1.7e-77	75.7
WP_163601421.1\|726780_726996_+	hypothetical protein	NA	NA	NA	NA
WP_163601422.1\|727858_728179_+	hypothetical protein	NA	NA	NA	NA
WP_163601423.1\|728322_728490_+	hypothetical protein	E9LUM1	Lactobacillus_phage	9.8e-12	75.0
WP_163601424.1\|728526_728736_+	hypothetical protein	E9LUM2	Lactobacillus_phage	1.1e-23	73.9
WP_035435754.1\|729009_729531_+	single-stranded DNA-binding protein	A0A286QMN2	Streptococcus_phage	1.3e-30	50.7
WP_163601425.1\|729544_730237_+	helix-turn-helix domain-containing protein	A0A1W6JQ30	Staphylococcus_phage	1.4e-14	46.2
WP_163601426.1\|730307_730757_+	hypothetical protein	NA	NA	NA	NA
WP_035435748.1\|730874_731339_+	hypothetical protein	A0A0A1EL23	Lactobacillus_phage	7.2e-44	59.7
WP_163601427.1\|731788_732790_+	hypothetical protein	A0A1L2JY39	Aeribacillus_phage	1.7e-05	25.3
WP_163601428.1\|732831_733278_+	hypothetical protein	NA	NA	NA	NA
WP_021349255.1\|733351_733558_-	CsbD family protein	NA	NA	NA	NA
WP_070447750.1\|733988_734579_+	hypothetical protein	D2IYV7	Enterococcus_phage	4.7e-24	33.0
WP_163601429.1\|734717_735224_+	HNH endonuclease	B8R694	Lactobacillus_phage	6.0e-44	58.6
WP_163601782.1\|735422_735884_+\|terminase	phage terminase small subunit P27 family	B8R648	Lactobacillus_phage	8.2e-40	52.3
WP_163601783.1\|735883_737785_+\|terminase	terminase large subunit	B8R649	Lactobacillus_phage	1.9e-244	63.6
WP_163601430.1\|737800_737983_+	hypothetical protein	NA	NA	NA	NA
WP_163601431.1\|737982_739203_+\|portal	phage portal protein	B8R650	Lactobacillus_phage	2.1e-95	48.4
WP_163601432.1\|739135_740914_+\|capsid	phage major capsid protein	B8R651	Lactobacillus_phage	6.9e-135	49.5
WP_163601433.1\|740934_741237_+	hypothetical protein	NA	NA	NA	NA
WP_163601434.1\|741208_741577_+\|head	phage head closure protein	B8R652	Lactobacillus_phage	7.5e-20	42.3
WP_163601435.1\|741569_742007_+	hypothetical protein	A0A286QS23	Streptococcus_phage	3.3e-30	50.0
WP_163601436.1\|742006_742378_+	DUF806 family protein	A0A286QR13	Streptococcus_phage	4.7e-14	37.1
WP_163586955.1\|742389_743013_+	hypothetical protein	A0A286QSF8	Streptococcus_phage	2.0e-12	27.9
WP_163601437.1\|743079_743409_+	hypothetical protein	NA	NA	NA	NA
WP_163601438.1\|743613_747804_+	transglycosylase SLT domain-containing protein	E9LUR1	Lactobacillus_phage	1.1e-26	31.6
WP_163601439.1\|747866_748706_+\|tail	phage tail family protein	A0A2H4JBY6	uncultured_Caudovirales_phage	3.6e-17	28.0
WP_163601784.1\|749702_751307_+	hypothetical protein	E9LUJ4	Lactobacillus_phage	9.2e-38	25.6
WP_163601440.1\|751293_753579_+	hypothetical protein	E9LUJ5	Lactobacillus_phage	4.7e-120	49.9
WP_163601441.1\|753571_753763_+	hypothetical protein	E9LUJ6	Lactobacillus_phage	1.1e-14	82.0
WP_163601442.1\|753765_754005_+	hypothetical protein	NA	NA	NA	NA
WP_163601443.1\|754018_754489_+	hypothetical protein	NA	NA	NA	NA
WP_163601444.1\|754488_754872_+	hypothetical protein	NA	NA	NA	NA
WP_163601445.1\|754885_755383_+	hypothetical protein	NA	NA	NA	NA
WP_163601446.1\|755521_755776_+	hypothetical protein	D2KRC5	Lactobacillus_phage	8.5e-15	49.4
WP_163601447.1\|755772_756207_+	hypothetical protein	A0A0A1ELI5	Lactobacillus_phage	7.2e-14	40.9
WP_163601448.1\|756157_757321_+	LysM peptidoglycan-binding domain-containing protein	A0A075KJD2	Lactobacillus_phage	1.6e-39	39.1
WP_163601268.1\|757506_758469_+\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_163601449.1\|759660_759861_+	hypothetical protein	NA	NA	NA	NA
WP_012391635.1\|759938_760631_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_163601785.1\|760555_761506_+\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	4.5e-16	30.2
WP_016363744.1\|761686_762007_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_163601450.1\|762378_762720_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_163601451.1\|762846_765993_+	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_163601452.1\|766654_767236_+	recombinase family protein	A0A219YA40	Aeromonas_phage	2.0e-19	35.5
WP_163601453.1\|768010_768931_-\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	5.8e-37	35.0
WP_088460938.1\|769054_769198_+	MFS transporter	NA	NA	NA	NA
WP_163601454.1\|769280_769643_-	hypothetical protein	NA	NA	NA	NA
WP_163601455.1\|769788_770814_+\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	1.3e-42	35.1
WP_163601786.1\|770886_771534_+\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	2.5e-55	51.2
WP_163601456.1\|771562_771760_+	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_079247419.1\|772258_773065_-\|integrase	site-specific integrase	E9LUS1	Lactobacillus_phage	3.1e-66	50.4
WP_163601457.1\|773214_773913_+\|transposase	transposase	A0A0C5AJ29	Paenibacillus_phage	1.8e-22	31.7
WP_163601787.1\|773849_774758_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	1.5e-13	26.9
WP_163601458.1\|775168_775849_+	serine dehydratase	NA	NA	NA	NA
WP_049183612.1\|775849_776737_+	L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha	NA	NA	NA	NA
WP_049183615.1\|776733_777048_+	metal-sulfur cluster assembly factor	NA	NA	NA	NA
WP_079247391.1\|777511_778474_+	YSIRK-type signal peptide-containing protein	NA	NA	NA	NA
WP_062813232.1\|780429_781599_+	hydroxymethylglutaryl-CoA synthase	NA	NA	NA	NA
WP_049183626.1\|781953_782580_-	transcriptional repressor LexA	A0A1B2APZ1	Phage_Wrath	2.3e-16	54.3
781792:781816	attR	NA	NA	NA	NA
WP_057727693.1\|782735_782987_+	DUF896 domain-containing protein	NA	NA	NA	NA
WP_003685231.1\|783063_783291_+	YneF family protein	NA	NA	NA	NA
WP_163601459.1\|783357_783990_-	1-acyl-sn-glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
WP_062813231.1\|784085_784838_+\|tRNA	tRNA1(Val) (adenine(37)-N6)-methyltransferase	NA	NA	NA	NA
WP_003681959.1\|784830_785121_+	GIY-YIG nuclease family protein	W8W2G4	Invertebrate_iridovirus	1.4e-05	38.0
WP_049183632.1\|785274_786054_+	30S ribosomal protein S2	NA	NA	NA	NA
WP_062813229.1\|786144_787023_+	elongation factor Ts	NA	NA	NA	NA
WP_062813228.1\|787103_787829_+	UMP kinase	NA	NA	NA	NA
WP_021815941.1\|787828_788389_+	ribosome recycling factor	NA	NA	NA	NA
WP_057727688.1\|788521_789289_+	isoprenyl transferase	R9W0U9	Flavobacterium_phage	5.9e-19	36.0
WP_012391092.1\|789305_790094_+	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_057727687.1\|790115_791387_+\|protease	RIP metalloprotease RseP	NA	NA	NA	NA
WP_049183645.1\|791420_793142_+\|tRNA	proline--tRNA ligase	A0A2K9L6B6	Tupanvirus	1.8e-07	25.9

DBSCAN-SWA_8

811620 : 866027

Staphylococcus_phage(28.57%)

tRNA,protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_049183669.1\|811620_812517_+\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
WP_163601464.1\|812527_813493_+	riboflavin biosynthesis protein RibF	NA	NA	NA	NA
WP_049184606.1\|815101_815467_-	hypothetical protein	NA	NA	NA	NA
WP_057728137.1\|815592_816639_+	heat-inducible transcriptional repressor HrcA	NA	NA	NA	NA
WP_014562322.1\|816649_817237_+	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_057728138.1\|817273_819130_+	molecular chaperone DnaK	A0A2P1EIW2	Megavirus	4.2e-135	45.4
WP_062814009.1\|819241_820402_+	molecular chaperone DnaJ	E3T4P7	Cafeteria_roenbergensis_virus	6.5e-17	29.3
WP_062814008.1\|820744_821356_+	imidazole glycerol phosphate synthase subunit HisH	NA	NA	NA	NA
WP_049184619.1\|821383_822136_+	imidazole glycerol phosphate synthase subunit HisF	NA	NA	NA	NA
WP_163601327.1\|822710_823643_+\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	6.7e-41	37.7
WP_163601789.1\|823651_824311_+\|transposase	transposase	A0A0C5AJ29	Paenibacillus_phage	6.4e-22	33.3
WP_163601788.1\|824247_825156_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	8.9e-14	26.9
WP_163601465.1\|825827_827660_+	elongation factor 4	E4ZFJ7	Streptococcus_phage	1.9e-23	26.1
WP_049182614.1\|828167_828671_-	hypothetical protein	NA	NA	NA	NA
WP_049182615.1\|828706_829330_-	histidine phosphatase family protein	NA	NA	NA	NA
WP_163601466.1\|830703_831777_+	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	2.0e-89	47.9
WP_062814005.1\|831788_832964_+	phosphoglycerate dehydrogenase	M1NSB9	Streptococcus_phage	8.4e-89	41.5
WP_049183413.1\|833228_833699_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	4.0e-26	44.1
WP_062814004.1\|833691_834885_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	2.5e-96	48.4
WP_057727952.1\|834871_835480_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.4e-26	39.1
WP_163601467.1\|835479_836538_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	1.3e-40	33.9
WP_163601468.1\|836947_837433_-	flavodoxin	NA	NA	NA	NA
WP_062814002.1\|837605_838778_+	cysteine desulfurase	NA	NA	NA	NA
WP_163601469.1\|840123_840804_-	DUF554 domain-containing protein	NA	NA	NA	NA
WP_062814000.1\|840978_841506_+	peptide-methionine (S)-S-oxide reductase MsrA	NA	NA	NA	NA
WP_163601470.1\|841780_841921_+	hypothetical protein	NA	NA	NA	NA
WP_062813999.1\|842010_842859_+	MetQ/NlpA family ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_062813998.1\|842871_843390_+	peptide-methionine (S)-S-oxide reductase MsrA	NA	NA	NA	NA
WP_049185089.1\|843829_844015_+	hypothetical protein	NA	NA	NA	NA
WP_163601471.1\|844247_845039_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_049185087.1\|845127_845571_+	phosphate-starvation-inducible protein PsiE	NA	NA	NA	NA
WP_049185085.1\|845585_846398_+	bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase	NA	NA	NA	NA
WP_062813997.1\|846459_847101_-	thiamine phosphate synthase	NA	NA	NA	NA
WP_163601472.1\|847265_848063_-	bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase	NA	NA	NA	NA
WP_048339929.1\|848064_848850_-	hydroxyethylthiazole kinase	NA	NA	NA	NA
WP_163601473.1\|849188_851156_+	hypothetical protein	NA	NA	NA	NA
WP_003688751.1\|851585_851873_+\|transposase	transposase	NA	NA	NA	NA
WP_163601474.1\|852805_853192_-\|transposase	transposase	NA	NA	NA	NA
WP_163601475.1\|853332_854472_+\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	1.4e-43	33.6
WP_062813994.1\|854583_855783_-	acetylornithine deacetylase	NA	NA	NA	NA
WP_062813992.1\|856206_857922_+	hypothetical protein	NA	NA	NA	NA
WP_049184599.1\|858536_859103_+	hypothetical protein	NA	NA	NA	NA
WP_062813991.1\|859276_860230_-	L-lactate dehydrogenase	NA	NA	NA	NA
WP_049184586.1\|860838_861165_+	hypothetical protein	NA	NA	NA	NA
WP_062813989.1\|861217_862180_+	50S ribosomal protein L11 methyltransferase	NA	NA	NA	NA
WP_057727636.1\|862179_862929_+	16S rRNA (uracil(1498)-N(3))-methyltransferase	NA	NA	NA	NA
WP_062813988.1\|862988_863330_+	hypothetical protein	NA	NA	NA	NA
WP_049184580.1\|863345_865580_+	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	A0A218M393	Acidovorax_phage	6.8e-07	43.5
WP_049184579.1\|865589_866027_+\|tRNA	D-tyrosyl-tRNA(Tyr) deacylase	NA	NA	NA	NA

DBSCAN-SWA_9

934756 : 943024

Staphylococcus_phage(28.57%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_062813950.1\|934756_935959_+\|tRNA	CCA tRNA nucleotidyltransferase	H7BUW3	unidentified_phage	7.6e-45	48.6
WP_062813949.1\|935971_937858_+	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	1.0e-51	29.3
WP_062813948.1\|937923_938883_+	thymidylate synthase	A0A0N9SH48	Staphylococcus_phage	7.0e-118	63.1
WP_062813947.1\|938894_939392_+	dihydrofolate reductase	A0A1Y0SUI9	Pseudomonas_phage	2.4e-21	37.3
WP_062813946.1\|939377_940007_-	hemolysin III family protein	NA	NA	NA	NA
WP_003684926.1\|940173_941016_+	DegV family protein	A0A0N9SI50	Staphylococcus_phage	3.0e-16	33.3
WP_062813945.1\|941149_942328_-	3-phosphoglycerate dehydrogenase	M1NSB9	Streptococcus_phage	2.5e-61	36.3
WP_012391200.1\|942397_943024_+	chloramphenicol acetyltransferase	A0A2R8FE91	Brazilian_cedratvirus	4.0e-13	40.8

DBSCAN-SWA_10

1181854 : 1189912

Staphylococcus_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_135293564.1\|1181854_1182629_+\|transposase	IS5 family transposase	A0A0N9SJT9	Paenibacillus_phage	4.8e-16	36.4
WP_069775620.1\|1182679_1184371_+	fibronectin/fibrinogen-binding protein	M1I5P2	Paramecium_bursaria_Chlorella_virus	8.5e-10	36.2
WP_163601543.1\|1185500_1186721_+\|transposase	IS256 family transposase	A0A0K2CZ57	Paenibacillus_phage	1.1e-94	46.2
WP_012391386.1\|1186909_1187326_-	arsenate reductase (thioredoxin)	A0A2H4PQT9	Staphylococcus_phage	1.0e-25	46.8
WP_012391387.1\|1187337_1188375_-	ACR3 family arsenite efflux transporter	NA	NA	NA	NA
WP_012391388.1\|1188425_1188743_-	winged helix-turn-helix transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	4.0e-22	51.1
WP_163601545.1\|1188895_1189912_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	5.6e-33	31.1

DBSCAN-SWA_11

1394447 : 1467210

Staphylococcus_phage(18.18%)

integrase,tRNA,protease,transposase

attL 1466647:1466706|attR 1467848:1467957

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_062813692.1\|1394447_1395371_-\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	6.7e-33	32.1
WP_163601601.1\|1395473_1395851_+	DUF302 domain-containing protein	NA	NA	NA	NA
WP_062813762.1\|1395895_1397542_-	polysaccharide biosynthesis protein	NA	NA	NA	NA
WP_003683636.1\|1397654_1397918_-	type II toxin-antitoxin system HicB family antitoxin	NA	NA	NA	NA
WP_057728147.1\|1398238_1400656_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	66.8
WP_062813761.1\|1400984_1401725_+	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_062813760.1\|1401983_1403225_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	1.1e-107	55.1
WP_057728100.1\|1403227_1404019_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	4.7e-43	38.7
WP_049182478.1\|1404301_1405489_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	3.5e-143	67.6
WP_057728099.1\|1405682_1406414_+	hypothetical protein	NA	NA	NA	NA
WP_062813758.1\|1406497_1407034_-	DNA-3-methyladenine glycosylase I	NA	NA	NA	NA
WP_062813757.1\|1407072_1408506_-	MFS transporter	NA	NA	NA	NA
WP_021349073.1\|1408627_1409083_+	transcriptional repressor	NA	NA	NA	NA
WP_062813756.1\|1409181_1410549_-	amino acid permease	NA	NA	NA	NA
WP_003683616.1\|1410720_1410879_+	hypothetical protein	NA	NA	NA	NA
WP_049182473.1\|1410888_1411506_+	LysR family transcriptional regulator substrate-binding protein	NA	NA	NA	NA
WP_003686118.1\|1413462_1413894_-	Hsp20/alpha crystallin family protein	NA	NA	NA	NA
WP_003686116.1\|1414105_1414609_-	acyl-CoA thioesterase	NA	NA	NA	NA
WP_163601604.1\|1414915_1415746_-	LysM peptidoglycan-binding domain-containing protein	A0A249XZV3	Enterococcus_phage	1.2e-20	71.2
WP_062813754.1\|1416155_1417226_-	NAD(P)-dependent alcohol dehydrogenase	E3SJ82	Synechococcus_phage	3.9e-08	25.5
WP_163601607.1\|1417434_1418772_-	purine permease	NA	NA	NA	NA
WP_062813752.1\|1418923_1419796_-	hypothetical protein	NA	NA	NA	NA
WP_049184625.1\|1419804_1420386_-	anaerobic ribonucleoside-triphosphate reductase activating protein	A0A0C5K925	Enterococcus_phage	1.1e-52	59.1
WP_062814138.1\|1420330_1422547_-	anaerobic ribonucleoside-triphosphate reductase	A0A0C5KKX3	Enterococcus_phage	2.8e-247	58.7
WP_049184624.1\|1422913_1423597_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_049184622.1\|1423619_1424441_-	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_076810948.1\|1424800_1425025_-	hypothetical protein	NA	NA	NA	NA
WP_003684211.1\|1432191_1432440_-	DUF1797 family protein	NA	NA	NA	NA
WP_076811130.1\|1432773_1433793_-	flippase-like domain-containing protein	NA	NA	NA	NA
WP_049183836.1\|1433794_1434820_-	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_049183834.1\|1434812_1436030_-	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_062813751.1\|1436245_1437976_-	phosphoenolpyruvate--protein phosphotransferase	NA	NA	NA	NA
WP_049183828.1\|1437977_1438244_-	phosphocarrier protein HPr	NA	NA	NA	NA
WP_057728032.1\|1438373_1438616_-	hypothetical protein	NA	NA	NA	NA
WP_057728031.1\|1438789_1441036_+\|protease	ATP-dependent Clp protease ATP-binding subunit	K4FB40	Cronobacter_phage	4.9e-122	40.6
WP_163601610.1\|1441339_1442047_+	NUDIX hydrolase	NA	NA	NA	NA
WP_057728029.1\|1442173_1442749_+	cysteine hydrolase	G3MA16	Bacillus_virus	1.5e-27	37.4
WP_163601612.1\|1444571_1445132_-	ECF transporter S component	NA	NA	NA	NA
WP_057728027.1\|1445305_1445977_+\|transposase	IS607 family transposase	A0A1V0SJI5	Klosneuvirus	1.2e-34	41.2
WP_062813747.1\|1445912_1447250_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	G3MB42	Bacillus_virus	6.9e-63	35.8
WP_057728025.1\|1447498_1448218_+	MucBP domain-containing protein	NA	NA	NA	NA
WP_062813745.1\|1448228_1449017_+	pyrroline-5-carboxylate reductase	A0A1X9I6T5	Streptococcus_phage	4.4e-25	34.5
WP_057728023.1\|1449006_1449891_+	DMT family transporter	NA	NA	NA	NA
WP_163601797.1\|1449969_1451214_+	carboxylate--amine ligase	NA	NA	NA	NA
WP_163601255.1\|1451355_1451493_-	hypothetical protein	NA	NA	NA	NA
WP_163601614.1\|1451618_1452299_-	hypothetical protein	NA	NA	NA	NA
WP_015639302.1\|1452311_1453172_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	3.7e-17	28.0
WP_003684176.1\|1453158_1453536_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_163601616.1\|1453644_1454577_-	dTDP-glucose 4,6-dehydratase	M1H4P8	Acanthocystis_turfacea_Chlorella_virus	3.3e-56	39.6
WP_057728045.1\|1454597_1455506_-	glycosyltransferase	NA	NA	NA	NA
WP_057728044.1\|1455523_1456576_-	sugar transferase	NA	NA	NA	NA
WP_163601618.1\|1456593_1458174_-	peptide chain release factor 3	A0A1S5SF82	Streptococcus_phage	3.0e-33	25.6
WP_163601620.1\|1458392_1459370_-	glycosyltransferase family 2 protein	B9UDL7	Salmonella_phage	1.7e-47	36.7
WP_163601622.1\|1459458_1460568_-	AI-2E family transporter	NA	NA	NA	NA
WP_163601624.1\|1460567_1461500_-	glycosyltransferase family 2 protein	V5USA4	Oenococcus_phage	7.6e-77	50.0
WP_163601626.1\|1461540_1462473_-\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	2.8e-39	37.1
WP_075667525.1\|1462658_1463222_-	hypothetical protein	NA	NA	NA	NA
WP_163601628.1\|1463364_1464960_-	hydrolase Nlp/P60	A0A1W6DXV0	Rhodococcus_phage	1.6e-13	48.7
1466647:1466706	attL	NA	NA	NA	NA
WP_100224342.1\|1466757_1467210_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	A0A0N9SIX5	Staphylococcus_phage	6.4e-05	31.2
WP_100224342.1\|1466757_1467210_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	A0A0N9SIX5	Staphylococcus_phage	6.4e-05	31.2
1467848:1467957	attR	NA	NA	NA	NA

DBSCAN-SWA_12

1527492 : 1538930

Erysipelothrix_phage(37.5%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_057727515.1\|1527492_1528152_-	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	1.6e-41	43.8
WP_049184701.1\|1529041_1529398_-	hypothetical protein	NA	NA	NA	NA
WP_163601800.1\|1529770_1530679_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	2.0e-13	26.9
WP_081011445.1\|1530615_1531314_-	helix-turn-helix domain-containing protein	A0A0C5AJ29	Paenibacillus_phage	2.3e-22	31.7
WP_163601801.1\|1531432_1531669_+	hypothetical protein	H7BV84	unidentified_phage	9.7e-05	60.6
WP_163601672.1\|1531779_1531947_+	hypothetical protein	NA	NA	NA	NA
WP_163601674.1\|1532010_1533528_+	recombinase family protein	A0A2K5B2B2	Erysipelothrix_phage	2.6e-106	40.6
WP_128492372.1\|1533534_1533948_+	hypothetical protein	NA	NA	NA	NA
WP_128492792.1\|1533963_1535529_+	recombinase family protein	A0A2K5B2B4	Erysipelothrix_phage	4.5e-130	49.5
WP_163601676.1\|1535591_1536134_-	PIN domain-containing protein	NA	NA	NA	NA
WP_128492370.1\|1536130_1536460_-	STAS-like domain-containing protein	NA	NA	NA	NA
WP_128492369.1\|1536471_1537365_-	ATP-binding protein	J7KDG8	Streptococcus_phage	2.6e-13	34.1
WP_163601678.1\|1537550_1538930_-	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	A0A2K5B251	Erysipelothrix_phage	4.7e-131	52.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP047585

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection